bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thalamic Gangliocytoma in a Pediatric Patient—An Incidental Diagnosis
Authors: Oyuela-Mancera Martha E. , Maturana Jennifer R. , Rodriguez Laura C. , Perez-Acosta Juan J. , Rodado-Mieles César E. , Bastidas Nicolás 
Published: July 2023

AbstractGangliogliomas and gangliocytomas are ganglion cell tumors that arise from the neuroepithelium. The most marked difference between both tumors is that gangliogliomas have a neoplastic glial component. At the same time, gangliocytomas comprise mature dysplastic ganglion cells with no neoplastic glial component. A 4-year-old male patient, a product of third gestation, was admitted to the emergency department after presenting obstructive bronchial symptoms secondary to viral infection with bacterial coinfection; during this condition, he accidentally fell from the crib (1-m high), with subsequent mild cranioencephalic trauma. A noncontrast cranial computed tomography showed a solid mass in the right thalamus and generated basal ganglion edema. A gangliocytoma grade II was confirmed by magnetic resonance imaging and histopathological result. Our unique case demonstrates an atypical location not previously reported in the pediatric population.
Trapeziectomy versus Maïa Prosthesis in Trapeziometacarpal Osteoarthritis
Authors: Windhofer Christian M. , Neureiter Johann , Schauer Josef , Zimmermann Georg , Hirnsperger Christoph 
Published: July 2023

Abstract
Background Osteoarthritis at the base of the thumb is the most frequent osteoarthritis of the hand. Trapeziectomy in a broad variety of surgical methods have been proposed to achieve pain reduction and improvement of thumb function. A well-known disadvantage is the long recovery time. Arthroplasty of the thumb carpometacarpal joint is a competing new method for this indication with different revision and complication rates reported.
Purposes The aim of this study is to assess whether there are significant differences in outcome during the first 12 months and time return to work after either, implant of a Maïa joint prosthesis, or trapeziectomy with tendon interposition after Weilby.
Patients and Methods This clinical follow-up study compares the efficacy of total basal joint replacement using the Maïa prosthesis with tendon interposition arthroplasty in 59 thumbs. Clinical, functional, and radiological results at preoperative, 3-, 6-, and 12-month postoperative are presented.
Results We found a significant shorter return to work in the prosthesis group with 4.5 compared with 8.6 weeks. In addition to a significant difference in pain reduction with a better Mayo wrist score in the Maïa group after 3 months. The scores are closer after 6 months and nearly match after 12 months. Measurement of the pinch grip showed a parallel course. A radiological loosening of the cup in two patients was detected after 12 months.
Conclusion Implantation of Maïa prosthesis enables a significant shorter recovery but is associated with the risk of loosening and higher costs.
Level of Evidence Level IV, case–control study.
The Impact of Uric Acid on Human Health: Beyond Gout and Kidney Stones
Authors: Anaizi Nasr 
Published: July 2023

AbstractIn most primates, including humans, uric acid (UA) is the end product of purine metabolism due to the loss of hepatic uricase activity during evolution. This loss resulted in higher serum urate concentrations (3.5–7.5 mg/dL) than normally observed in other mammals (0.05–2 mg/dL). About 70% of the daily urate burden is eliminated via the kidneys and the remainder via the intestines, where gut bacteria break it down. Urate is freely filtered through the glomerular capillaries, and most of the filtered urate is reabsorbed so that only an amount equivalent to about 10% of the filtered load is excreted in the urine. Virtually all of the renal urate reabsorption takes place in proximal convoluted tubules. Many transport proteins connected with urate have been identified. However, the best studied are URAT1 and GLUT9, which function in concert to translocate urate from the proximal tubule lumen to the peritubular fluid, the first in the apical membrane and the second in the basolateral membrane. Genetic mutations, as well as drugs that alter the function of these transporters, can affect urate homeostasis resulting in abnormal serum levels, which may, in turn, be involved in the pathogenesis of chronic metabolic and inflammatory diseases, including most features of the metabolic syndrome, hypertension, cardiovascular disease, and chronic kidney disease. Several mechanisms are thought to provide the link between urate and these disorders, including reactive oxygen species (oxidative stress) and both acute and chronic inflammation. This mini-review summarizes the basic human biology of UA and its association with and potential involvement in developing chronic diseases beyond gout and nephrolithiasis.
A cytohistopathological correlation study of skin lesions in leprosy: An experience in a tertiary care hospital in South India
Authors: Padma Madana , Katta Ramya 
Published: July 2023

Objectives:
Leprosy is a granulomatous disease caused by Mycobacterium leprae. Early detection and clinical diagnosis remain a challenge, especially in paucibacillary cases and initial lesions during early phases of leprosy. Use of cytological methods can reduce time for diagnosis, especially in peripheral centers. The present study was taken up to calculate the correlation between cytology and histopathology of skin lesions in leprosy.

Materials and Methods:
This study is a 2-year retrospective observational study taken up in the Department of Pathology, Rangaraya Medical College and Government General Hospital, Kakinada, Andhra Pradesh. A total of 49 cases of clinically suspected leprosy were included in the study. Skin biopsies and cytological smears were examined in all cases.

Results:
A total of 49 cases of clinically suspected leprosy were included in the study. The age incidence ranged between 9 and 72 years. There was a male preponderance. The overall diagnostic accuracy of fine-needle aspiration smears was 83.3% and that of slit-skin smears was 62.1%.

Conclusions:
Cytological examination being a simple, less time-consuming, and easy technique can enhance the diagnostic accuracy in detection of leprosy and act as an adjunct to clinical diagnosis.
Unveiling the job characteristics-creativity rapport through the bridge of thriving: a self-determination perspective from the Chinese hospitality sector
Authors: Farid Hasan , Zhang Yang , Tian Ming , Raza Jamshed , Lu Shiyao 
Published: July 2023

AbstractGrounding on self-determination theory, this study proposes that job characteristics (task variety and skill variety) enhance employees’ creativity through thriving at work. It also aims to examine the boundary condition of managerial coaching for the link between job characteristics and thriving. A time-lagged dyadic data collected from 313 frontline hospitality individuals’ analyses performed through AMOS and PROCESS macro show that job characteristics promote individuals’ thriving and thriving affects individuals’ creativity positively. Skill variety as compared to task variety was found to be more strongly affecting thriving at work. Thriving mediates job characteristics and creativity. Moreover, managerial coaching significantly moderates the effects of job characteristics on thriving. This study supports the self-determination perspective of job characteristics, thriving, creativity and managerial coaching in the Chinese hospitality sector.
Integration of Environmental, Social, and Governance (ESG) criteria: their impacts on corporate sustainability performance
Authors: de Souza Barbosa Anrafel , da Silva Maria Cristina Basilio Crispim , da Silva Luiz Bueno , Morioka Sandra Naomi , de Souza Vinícius Fernandes 
Published: July 2023

AbstractIn a corporate sustainability context, scholars have been studying internal and external relations provided by Environmental, Social, and Governance (ESG) criteria, mostly from the organizational perspective. Therefore, the main objective of this paper is to map and analyze the literature on the impacts of integrating ESG criteria on corporate sustainability performance from different points of view. The methodology used followed the Preferred Report Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, corroborated by a critical analysis. The results indicate that the integration of ESG criteria, observed from different perspectives, strengthens corporate sustainability performance. They also revealed narrowing gaps in the literature regarding methodological analysis. Most of the papers in the analyzed sample use company-level data and employ regression analysis in their analysis. The present study concludes that companies, regardless of nationality, follow the guidelines of ESG criteria integration and such procedure brings several benefits. It points to the lack of more confirmatory research approaches from a workers’ perspective, as the interest remains in the economic-environmental realm from the organizations’ point of view. The absence of such evidence points to a gap in the literature that suggests the need for new study initiatives.
Airspace in the Anthropocene
Authors: Mackay Anson W. 
Published: July 2023

Abstract
Technologies for manipulating the weather and climate have long been around, especially since the early 1950s. Weather modification applications were quickly weaponised to influence war and protest, until the 1978 UN Convention on the Prohibition of Military or any other hostile use of Environmental Modification Techniques. Reviewed interest in controlling weather and climate has grown again since. Technology to modify weather has been used consistently to modify weather at local scales, but regional applications are now being developed to mitigate impacts of wide-scale drought. Interest in climate modification technologies has grown rapidly in the past 15 years as back-stop solutions to the problem of global warming. Climate modification technologies (often called geoengineering or climate engineering) can largely be classed as either greenhouse gas removal or radiation management, the latter being more controversial. However, there is widespread concern as to the implications of geoengineering in terms of social justice and human rights; climate modification does not recognise political boundaries. In this paper, I will provide a brief review of how humanity has influenced the atmospheric environment above us since the Industrial Revolution, and how this chemical modification of the atmosphere kills millions of people every year, especially those who are poor and vulnerable. I will summarise major geoengineering techniques in play today, highlighting issues related to governance and human rights, relevant to this special issue on The Airspace Tribunal.
Spin-dependent electrified protein interfaces for probing the CISS effect
Authors: Gupta Ritu , Chinnasamy Hariharan V. , Sahu Dipak , Matheshwaran Saravanan , Sow Chanchal , Chandra Mondal Prakash 
Published: July 2023

Bio-spinterfaces present numerous opportunities to study spintronics across the biomolecules attached to (ferro)magnetic electrodes. While it offers various exciting phenomena to investigate, it is simultaneously challenging to make stable bio-spinterfaces as biomolecules are sensitive to many factors that it encounters during thin-film growth to device fabrication. The chirality-induced spin-selectivity effect is an exciting discovery, demonstrating an understanding that a specific electron’s spin (either up or down) passes through a chiral molecule. The present work utilizes Ustilago maydis Rvb2 protein, an ATP-dependent DNA helicase (also known as Reptin), to fabricate bio-spintronic devices to investigate spin-selective electron transport through the protein. Ferromagnetic materials are well-known for exhibiting spin-polarization, which many chiral and biomolecules can mimic. We report herein spin-selective electron transmission through Rvb2 that exhibits 30% spin polarization at a low bias (+0.5 V) in a device configuration, Ni/Rvb2 protein/indium tin oxide measured under two different magnetic configurations. Our findings demonstrate that biomolecules can be put in circuit components without any expensive vacuum deposition for the top contact. The present study holds a remarkable potential to advance spin-selective electron transport in other biomolecules, such as proteins and peptides, for biomedical applications.
Skepi Creole Dutch
Authors: Jacobs Bart , Parkvall Mikael 
Published: July 2023

Abstract
This paper presents new Skepi Creole Dutch data from the late-18th century, found in the work of the German
scholar Ernst Karl Rodschied. The creole data include pronominal and verbal paradigms, a short 60-word excerpt from a private
letter, and around two dozen names for local flora. After briefly introducing Rodschied, we present the data and compare them to
the existing Skepi corpus.
Improving the anticorrosion property of outdoor fitness equipment via a novel Ti/Zr/Mo composite conversion coating
Authors: Wang Yiqun , Qian Xuzheng , Huang Feng , Fan Yingsong , Wang Tingting , Hu Lan 
Published: July 2023

Abstract
In recent years, a large number of outdoor fitness equipment have been newly built in China. In order to improve the anticorrosion property of outdoor fitness equipment, a new type of Ti/Zr/Mo conversion coating (TiZrMoCC) has been prepared on its surface. The surface morphology, element distribution, phase composition, and anticorrosion property were systematically measured, and the relationships between them were established. The results show that the optimal conversion temperature and time were 30 °C and 20 min, respectively. Under the optimal conversion parameters, the surface morphology of the TiZrMoCC is relatively flat and dense, and its phase compositions mainly consisted of TiO2, ZrO2, MoO3, Mo2O5 and Fe2O3, as well as a small quantity of Na3FeF6 and ZrF4. The TiZrMoCC could significantly reduce corrosion rate with the lower i

corr
, which is also confirmed by EIS results. The ACR of the TiZrMoCC decreased by nearly 63.5% compared to the Q235 matrix, and it has positive significance for protecting outdoor fitness equipment.
Decadal changes in rapid intensification of western North Pacific tropical cyclones modulated by the North Pacific Gyre Oscillation
Authors: Song Jinjie , Klotzbach Philip J , Dai Yifei , Duan Yihong 
Published: July 2023

Abstract
This study investigates the modulation of western North Pacific (WNP) tropical cyclone rapid intensification (RI) by the North Pacific Gyre Oscillation (NPGO) on decadal timescales. There is a significant inverse relationship between basinwide RI numbers during July–November and the simultaneous NPGO index from 1970 to 2021. During the positive NPGO phase, suppressed RI occurs over almost the entire WNP, with a distinctly different spatial distribution compared to the Pacific Decadal Oscillation-driven pattern of RI modulation. RI occurrence is significantly reduced over the eastern Philippine Sea (10°–25°N, 140°–155°E). This is primarily caused by enhanced negative low-level vorticity, which can be linked to the horizontal extent of the anomalous low-level anticyclone. By comparison, over the western Philippine Sea (10°–25°N, 125°–140°E), there are only weak RI occurrence changes due to offsetting influences of increased mid-level humidity and decreased low-level vorticity.
Creep behavior and characterization analysis of Mg-1.8Zn-0.3Ca alloy:a molecular dynamics analysis
Authors: Gowthaman S 
Published: July 2023

Abstract
The addition of Zinc (Zn) and Calcium (Ca) on the Magnesium (Mg) has invoked better biocompatibility in various orthopedic applications. But this addition (Zn and Ca) leads to inducing greater modifications in the creep characteristics. In this current study, a study on the creep characterization of Mg-1.8Zn-0.3Ca alloy has been examined using molecular dynamics analysis. The creep analysis has been focused on numerous grain sizes and creep environments such as temperature and pressure to analyze its effect on the creep performance and its features. Further, the creep performance, radial distribution function, dislocation length, and structural and microstructural transformation under various grain size and deformation time has been confirmed by the modifications in the deformation mechanism and its features under various grain size and creep conditions.
Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain
Authors: Kuehner Janise N , Walia Nevin R , Seong Rachel , Li Yangping , Martinez-Feduchi Paula , Yao Bing 
Published: July 2023

Abstract
Stress is adverse experience that require constant adaptation to reduce the emotional and physiological burden, or “allostatic load”, of an individual. Despite their everyday occurrence, a subpopulation of individuals is more susceptible to stressors, while others remain resilient with unknown molecular signatures. In this study, we investigated the contribution of the DNA modifications, 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), underlying the individual differences in stress susceptibility and resilience. Genome-wide 5mC and 5hmC profiles from 3- and 6-month adult male mice that underwent various durations of social defeat were generated. In 3-month animals, 5mC and 5hmC work in parallel and do not distinguish between stress-susceptible and resilient phenotypes, while in 6-month animals, 5mC and 5hmC show distinct enrichment patterns. Acute stress responses may epigenetically “prime” the animals to either increase or decrease their predisposition to depression susceptibility. In support of this, re-exposure studies reveal that the enduring effects of social defeat affect differential biological processes between susceptible and resilient animals. Finally, the stress-induced 5mC and 5hmC fluctuations across the acute-chronic-longitudinal time course demonstrate that the negative outcomes of chronic stress do not discriminate between susceptible and resilient animals. However, resilience is more associated with neuroprotective processes while susceptibility is linked to neurodegenerative processes. Furthermore, 5mC appears to be responsible for acute stress response, whereas 5hmC may function as a persistent and stable modification in response to stress. Our study broadens the scope of previous research offering a comprehensive analysis of the role of DNA modifications in stress-induced depression.
Change in Pain During Physical Activity Following Total Knee Arthroplasty: Associations With Improved Physical Function and Decreased Situational Pain Catastrophizing
Authors: Wilson Jenna M , Madden Victoria J , Pester Bethany D , Yoon JiHee , Papianou Lauren N , Meints Samantha M , Campbell Claudia M , Smith Michael T , Haythornthwaite Jennifer A , Edwards Robert R , Schreiber Kristin L 
Published: July 2023

Abstract

Background and Objectives
Knee osteoarthritis is one of the primary causes of chronic pain among older adults and because of the aging population, the number of total knee arthroplasties (TKAs) performed is exponentially increasing. While pain reduction is a goal of TKA, movement-evoked pain is rarely assessed pre- and post-TKA. We characterized the distributions of change in pain, function, and situational catastrophizing in patients from presurgery to 3 months postsurgery and explored associations among these pre–post changes.

Research Design and Methods
This prospective study longitudinally assessed movement-evoked pain, function, and situational catastrophizing in patients with knee osteoarthritis (N = 92) using in-person performance-based tests (6-min walk test [6MWT], stair-climb test [SCT]) prior to and 3 months after TKA. Patients also completed the Western Ontario McMaster Universities Scales (WOMAC) pain and function subscales, and Pain Catastrophizing Scale, presurgery and 3- and 6-months postsurgery.

Results
Movement-evoked pain and function on performance tests significantly improved from pre- to post-TKA. Improved SCT function was associated with reduced SCT pain and catastrophizing. Similarly, reduced pain during the SCT was associated with reduced catastrophizing during the SCT. However, 6MWT function was not associated with 6MWT pain or catastrophizing; yet reduced pain during the 6MWT was associated with reduced catastrophizing during the 6MWT. Reduced movement-evoked pain during both performance tests was consistently associated with improved WOMAC function and pain, whereas improved function on performance tests was inconsistently associated with WOMAC function and pain. Notably, greater movement-evoked pain on both performance tests at 3-month post-TKA was associated with worse WOMAC function and pain at 6 months, whereas better function on performance tests at 3 months was associated with better WOMAC function, but not related to WOMAC pain at 6 months.

Discussion and Implications
Findings highlight the importance of situation-specific and in vivo assessments of pain and catastrophizing during physical activity.
Establishing the Feasibility and Acceptability of a Caregiver Targeted Intervention to Improve Pain Assessment Among Persons With Dementia
Authors: Riffin Catherine , Brody Lilla , Mukhi Priya , Herr Keela , Pillemer Karl , Rogers Madeline , Henderson Charles R , Reid M Cary 
Published: July 2023

Abstract

Background and Objectives
Despite its prevalence and impact, pain is underdetected and undermanaged in persons with dementia. Family caregivers are well positioned to detect pain and facilitate its management in their care recipients, but they lack training in symptom recognition and communication. This study reports findings from a pilot trial evaluating the Pain Identification and Communication Toolkit (PICT), a multicomponent intervention that provides training in observational pain assessment and coaching in pain communication techniques.

Research Design and Methods
Family caregivers of persons with comorbid pain and moderate-to-advanced dementia were randomly assigned to PICT (n = 19) or a control condition (n = 15). Caregivers in the PICT group participated in four weekly sessions delivered by telephone with a trained interventionist; caregivers in the control group received an information pamphlet about pain and dementia. All participants completed surveys at baseline and 12 weeks. Caregivers in the intervention group also completed semistructured interviews at 12 weeks. Quantitative data were analyzed using descriptive statistics and t tests; qualitative data were analyzed using content analysis.

Results
All participants (100%) in the PICT group completed the intervention and most completed the 12-week assessment (94%). PICT randomized caregivers reported that the intervention helped them to feel more confident in their ability to recognize (67%) and communicate about pain symptoms (83%). At 12 weeks, caregivers in the PICT group showed a statistically significant improvement in self-efficacy in pain-related communication. In qualitative interviews, caregivers emphasized the utility of PICT’s components, including pain assessment tools, and offered considerations for future enhancements, such as technology-based adaptations and integration within care delivery systems.

Discussion and Implications
This pilot trial demonstrates that PICT is feasible to implement, acceptable to caregivers, and has the potential to improve confidence in recognizing and communicating about pain. Results support conducting a fully powered efficacy trial, an important step toward future integration into real-world care delivery.

Clinical Trial Registration Number
NCT03853291