bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing Liberal Democratic Values of Refugees in Germany and Their Origin Countries—Evidence for Cultural Self-Selection?
Authors: Fuchs Lukas M 
Published: December 2022

AbstractExpanding on a new body of literature on cultural self-selection, the present study investigates how refugees who arrived in Germany since 2013 relate to the general population of their countries of origin in terms of liberal democratic values. The cultural self-selection literature suggests that more liberal individuals may be more likely to flee to Germany. To trace cultural self-selection amongst refugees, a series of analyses is conducted: first, refugees of Iraqi, Russian, and Pakistani descent in Germany (IAB-BAMF-SOEP) and the general populations of their origin countries (World Values Survey) are statistically matched on socio-demographic characteristics and their democratic values are compared. After matching the samples, refugees express significantly higher support for liberal democratic values than the general population of their countries of origin. Second, a series of regression models is calculated, tracing three potential mechanisms for the observable differences: (1) acculturation effects in Germany, (2) the experience of being forcibly displaced, and (3) cultural self-selection. The results speak to the theoretical conjectures of the cultural self-selection literature. Liberal democratic values are not correlated with the time spent in Germany (acculturation), flight reasons, and past traumatic experiences (flight experience) but are positively correlated with a critical stance towards the government in the country of origin as well as with positive feelings towards Germany as the receiving society.
Dengue outbreak amongst travellers returning from Cuba—GeoSentinel surveillance network, January–September 2022
Authors: Díaz-Menéndez Marta , Angelo Kristina M , de Miguel Buckley Rosa , Bottieau Emmanuel , Huits Ralph , Grobusch Martin P , Gobbi Federico Giovanni , Asgeirsson Hilmir , Duvignaud Alexandre , Norman Francesca F , Javelle Emilie , Epelboin Loïc , Rothe Camilla , Chappuis Francois , Martinez Gabriela Equihua , Popescu Corneliu , Camprubí-Ferrer Daniel , Molina Israel , Odolini Silvia , Barkati Sapha , Kuhn Susan , Vaughan Stephen , McCarthy Anne , Lago Mar , Libman Michael D , Hamer Davidson H 
Published: December 2022

AbstractIncreasing numbers of travellers returning from Cuba with dengue virus infection were reported to the GeoSentinel Network from June to September 2022, reflecting an ongoing local outbreak. This report demonstrates the importance of travellers as sentinels of arboviral outbreaks and highlights the need for early identification of travel-related dengue.
Impact of streetlights on physiology, biochemistry and diversity of urban bryophyte: a case study on moss Semibarbula orientalis
Authors: Bhatt Upma , Sharma Shubhangani , Kumar Deepak , Soni Vineet 
Published: December 2022

Abstract
The use of artificial light at night is a very basic symbol of urbanization and has distorted many ecological, biochemical and physiological phenomena in plants, which have settled for millions of years in the biological system. Continuous illumination of light significantly alters the circadian rhythm of all organisms. The present study was focused to understand the effects of continuous light (CL) on the biochemistry and physiology of moss Semibarbula orientalis. It was observed that H2O2 accumulation and activities of chlorophyllase, phenylalanine ammonia-lyase, superoxide dismutase and catalase enzymes significantly enhanced in plants growing under streetlights. Similarly, plants under CL showed a marked reduction in photosynthetic performance. Specific fluxes (ABS/RC, TR/RC, ET/RC), phenomenological fluxes (ABS/CS, TR/CS, ET/CS), density of photosystem-II, quantum yield of photosynthesis and chlorophyll concentration markedly declined in plants growing under streetlights. Depletion in performance indices (PIcs and PIabs) and primary and secondary photochemistry [PHIO/(1 − PHIO) and PSIO/(1 − PSIO)] were also noticed, which indicated failure of adaptive strategies of photosystem-II, resulting in the loss of biomass of S. orientalis. Biomass decline is also shown by a decrease in coverage, which reduces the bryophyte species richness of the chosen locations. Present studies clearly indicate that artificial light at night drastically affects the moss population. The reduction in the dominating species, S. orientalis, improves species evenness and results in a slow growth rate.
Thyroid-Stimulating Hormone Levels within the Trimester-Specific Reference Intervals Are Correlated with Non–High-Density Lipoprotein Cholesterol and Remnant Cholesterol Concentrations in Pregnant Women
Authors: Wang Guocheng , Jin Feng , Xie Limin , Zhang Xiaofen , Zhang Yawei , Ni Xin , Li Wei , Zhang Guojun 
Published: December 2022

Abstract

Objective
Thyroid-stimulating hormone (TSH) levels are associated with serum lipid concentrations in the general nonpregnant population. Here, we aimed to establish trimester-specific reference intervals and to explore the associations of their variations within the specific reference intervals during pregnancy.

Methods
Trimester-specific reference intervals were established according to the Clinical and Laboratory Standard Institute EP28-A3c guidelines using a direct sampling method based on a large prospective cohort. After making one-to-one matches, correlation analyses between TSH and lipid index levels, especially within the reference intervals, were conducted.

Result
A total of 1648 pregnant women for TSH and 2045 subjects for lipids were recruited to establish the trimester-specific reference intervals. The upper reference limit (90% confidence interval) of TSH for pregnant women in the first trimester is 3.95 (3.66–4.29) mIU/L, which is very close to the default value (4.0 mIU/L) recommended by the American Thyroid Association in 2017. Apart from triglyceride and high-density lipoprotein cholesterol, TSH levels were positively associated with the serum concentrations of total cholesterol, low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol (non–HDL-C), and remnant cholesterol (RC) either in the entire range or within the specific reference intervals. Of note, the positive correlations between TSH and non–HDL-C and RC were, albeit similarly weak (r &lt; 0.25), relatively more robust (P &lt; .001).

Conclusion
In this study, we showed positive correlations between TSH and lipid components within trimester-specific reference intervals, highlighting the need for the integrated management of pregnant women over age 35 and with nonoptimal lipid status in China.
Safe-zone schools and the academic performance of children in mixed-status households: Evidence from the ‘between the lines’ study
Authors: Amuedo-Dorantes Catalina , Bucheli José R , Martinez-Donate Ana P 
Published: December 2022

Abstract
In response to the intensification of immigration enforcement in the interior of the USA, some school districts have implemented ‘safe-zone’ policies to protect students’ academic progression and well-being. Using primary data from a sample of US-born children of unauthorized migrants, we document the detrimental effect of stricter immigration enforcement on children’s educational outcomes and the benefits of safe-zone policies. Our analyses show that restricting immigration authorities’ access to schools and providing counseling on immigration-related issues are crucial policy components in strengthening children’s focus, effort, expectations, parental involvement, and relationships. These findings highlight the damaging impact of immigration enforcement on US-citizen children in mixed-status households and advance our understanding of the role of local policies in mitigating these effects.
An Analysis of Head and Neck Surgical Workload During Recent Combat Operations From 2002 to 2016
Authors: Stern Caryn A , Glaser Jacob J , Stockinger Zsolt T , Gurney Jennifer M 
Published: December 2022

ABSTRACT

Introduction
In battle-injured U.S. service members, head and neck (H&N) injuries have been documented in 29% who were treated for wounds in deployed locations and 21% who were evacuated to a Role 4 MTF. The purpose of this study is to examine the H&N surgical workload at deployed U.S. military facilities in Iraq and Afghanistan in order to inform training, needed proficiency, and MTF manning.

Materials and Methods
A retrospective analysis of the DoD Trauma Registry was performed for all Role 2 and Role 3 MTFs, from January 2002 to May 2016; 385 ICD-9 CM procedure codes were identified as H&N surgical procedures and were stratified into eight categories. For the purposes of this analysis, H&N procedures included dental, ophthalmologic, airway, ear, face, mandible maxilla, neck, and oral injuries. Traumatic brain injuries and vascular injuries to the neck were excluded.

Results
A total of 15,620 H&N surgical procedures were identified at Role 2 and Role 3 MTFs. The majority of H&N surgical procedures (14,703, 94.14%) were reported at Role 3 facilities. Facial bone procedures were the most common subgroup across both roles of care (1,181, 75.03%). Tracheostomy accounted for 16.67% of all H&N surgical procedures followed by linear repair of laceration of eyelid or eyebrow (8.23%) and neck exploration (7.41%). H&N caseload was variable.

Conclusions
H&N procedures accounted for 8.25% of all surgical procedures performed at Role 2 and Role 3 MTFs; the majority of procedures were eye (40.54%) and airway (18.50%). These data can be used as planning tools to help determine the medical footprint and also to help inform training and sustainment requirements for deployed military general surgeons especially if future contingency operations are more constrained in terms of resources and personnel.
On the cosmic web elongation in fuzzy dark matter cosmologies: Effects on density profiles, shapes, and alignments of haloes
Authors: Dome Tibor , Fialkov Anastasia , Mocz Philip , Schäfer Björn Malte , Boylan-Kolchin Michael , Vogelsberger Mark 
Published: December 2022

ABSTRACT
The fuzzy dark matter (FDM) scenario has received increased attention in recent years due to the small-scale challenges of the vanilla Lambda cold dark matter (ΛCDM) cosmological model and the lack of any experimental evidence for any candidate particle. In this study, we use cosmological N-body simulations to investigate high-redshift dark matter haloes and their responsiveness to an FDM-like power spectrum cutoff on small scales in the primordial density perturbations. We study halo density profiles, shapes, and alignments in FDM-like cosmologies (the latter two for the first time) by providing fits and quantifying departures from ΛCDM as a function of the particle mass m. Compared to ΛCDM, the concentrations of FDM-like haloes are lower, peaking at an m-dependent halo mass and thus breaking the approximate universality of density profiles in ΛCDM. The intermediate-to-major and minor-to-major shape parameter profiles are monotonically increasing with ellipsoidal radius in N-body simulations of ΛCDM. In FDM-like cosmologies, the monotonicity is broken, haloes are more elongated around the virial radius than their ΛCDM counterparts and less elongated closer to the centre. Finally, intrinsic alignment correlations, stemming from the deformation of initially spherically collapsing haloes in an ambient gravitational tidal field, become stronger with decreasing m. At z ∼ 4, we find a 6.4σ-significance in the fractional differences between the isotropized linear alignment magnitudes Diso in the m = 10−22 eV model and ΛCDM. Such FDM-like imprints on the internal properties of virialized haloes are expected to be strikingly visible in the high-z Universe.
Probing plasma physics with spectral index maps of accreting black holes on event horizon scales
Authors: Ricarte Angelo , Gammie Charles , Narayan Ramesh , Prather Ben S 
Published: December 2022

ABSTRACT
The Event Horizon Telescope (EHT) collaboration has produced the first resolved images of the supermassive black holes at the centre of our galaxy and at the centre of the elliptical galaxy M87. As both technology and analysis pipelines improve, it will soon become possible to produce spectral index maps of black hole accretion flows on event horizon scales. In this work, we predict spectral index maps of both M87* and Sgr A* by applying the general relativistic radiative transfer (GRRT) code ipole to a suite of general relativistic magnetohydrodynamic (GRMHD) simulations. We analytically show that the spectral index increases with increasing magnetic field strength, electron temperature, and optical depth. Consequently, spectral index maps grow more negative with increasing radius in almost all models, since all of these quantities tend to be maximized near the event horizon. Additionally, photon ring geodesics exhibit more positive spectral indices, since they sample the innermost regions of the accretion flow with the most extreme plasma conditions. Spectral index maps are sensitive to highly uncertain plasma heating prescriptions (the electron temperature and distribution function). However, if our understanding of these aspects of plasma physics can be tightened, even the spatially unresolved spectral index around 230 GHz can be used to discriminate between models. In particular, Standard and Normal Evolution (SANE) flows tend to exhibit more negative spectral indices than Magnetically Arrested Disc (MAD) flows due to differences in the characteristic magnetic field strength and temperature of emitting plasma.
Burden of Severe Illness Associated With Laboratory-Confirmed Influenza in Adults Aged 50–64 Years, 2010–2011 to 2016–2017
Authors: Kim Philip , Coleman Brenda , Kwong Jeffrey C , Plevneshi Agron , Hassan Kazi , Green Karen , McNeil Shelly A , Armstrong Irene , Gold Wayne L , Gubbay Jonathan , Katz Kevin , Kuster Stefan P , Lovinsky Reena , Matukas Larissa , Ostrowska Krystyna , Richardson David , McGeer Allison 
Published: December 2022

Abstract

Background
Understanding the burden of influenza is necessary to optimize recommendations for influenza vaccination. We describe the epidemiology of severe influenza in 50- to 64-year-old residents of metropolitan Toronto and Peel region, Canada, over 7 influenza seasons.

Methods
Prospective population-based surveillance for hospitalization associated with laboratory-confirmed influenza was conducted from September 2010 to August 2017. Conditions increasing risk of influenza complications were as defined by Canada's National Advisory Committee on Immunization. Age-specific prevalence of medical conditions was estimated using Ontario health administrative data. Population rates were estimated using Statistics Canada data.

Results
Over 7 seasons, 1228 hospitalizations occurred in patients aged 50–64 years: 40% due to A(H3N2), 30% A(H1N1), and 22% influenza B. The average annual hospitalization rate was 15.6, 20.9, and 33.2 per 100 000 in patients aged 50–54, 55–59, and 60–64 years, respectively; average annual mortality was 0.9/100 000. Overall, 33% of patients had received current season influenza vaccine; 963 (86%) had ≥1 underlying condition increasing influenza complication risk. The most common underlying medical conditions were chronic lung disease (38%) and diabetes mellitus (31%); 25% of patients were immunocompromised. The average annual hospitalization rate was 6.1/100 000 in those without and 41/100 000 in those with any underlying condition, and highest in those with renal disease or immunocompromise (138 and 281 per 100 000, respectively). The case fatality rate in hospitalized patients was 4.4%; median length of stay was 4 days (interquartile range, 2–8 days).

Conclusions
The burden of severe influenza in 50- to 64-year-olds remains significant despite our universal publicly funded vaccination program. These data may assist in improving estimates of the cost-effectiveness of new strategies to reduce this burden.
Porous marine snow differentially benefits chemotactic, motile, and nonmotile bacteria
Authors: Borer Benedict , Zhang Irene H , Baker Amy E , O'Toole George A , Babbin Andrew R 
Published: December 2022

AbstractParticulate organic carbon settling through the marine water column is a key process that regulates the global climate by sequestering atmospheric carbon. The initial colonization of marine particles by heterotrophic bacteria represents the first step in recycling this carbon back to inorganic constituents—setting the magnitude of vertical carbon transport to the abyss. Here, we demonstrate experimentally using millifluidic devices that, although bacterial motility is essential for effective colonization of a particle leaking organic nutrients into the water column, chemotaxis specifically benefits at intermediate and higher settling velocities to navigate the particle boundary layer during the brief window of opportunity provided by a passing particle. We develop an individual-based model that simulates the encounter and attachment of bacterial cells with leaking marine particles to systematically evaluate the role of different parameters associated with bacterial run-and-tumble motility. We further use this model to explore the role of particle microstructure on the colonization efficiency of bacteria with different motility traits. We find that the porous microstructure facilitates additional colonization by chemotactic and motile bacteria, and fundamentally alters the way nonmotile cells interact with particles due to streamlines intersecting with the particle surface.
The quiet side of debt: public debt management in advanced economies
Authors: Rommerskirchen Charlotte , van der Heide Arjen W 
Published: December 2022

Abstract
Whilst both the level and the make-up of public debt are high salience issues, the management of public debt seldom commands public attention. This study examines the quiet politics of public debt management in advanced capitalist societies, comparing debt management reforms and the everyday practice of debt management in Germany and the UK. We present evidence of two factors contributing to the political quietude around public debt management: a persistent absence of partisan contestation and conflict; and the dominance of ‘market discipline’ as an interpretative frame, which prevents changes in interest rates and debt servicing costs to be seen as the product of faulty debt management. We also find that this quietude creates a space for the coordination and cooperation between contemporary capitalist states and large dealer banks, whose capacities effectively to act within their respective domains depend on each other.
Self-Assembled Matrigel-Free iPSC-Derived Liver Organoids Demonstrate Wide-Ranging Highly Differentiated Liver Functions
Authors: Weng Yun , Han Simon , Sekyi Maria T , Su Tao , Mattis Aras N , Chang Tammy T 
Published: December 2022

AbstractHuman induced pluripotent stem cell (iPSC)-derived liver organoids serve as models of organogenesis, disease, drug screening, and regenerative medicine. Prevailing methods for generating organoids rely on Matrigel, whose batch-to-batch variability and xenogeneic source pose challenges to mechanistic research and translation to human clinical therapy. In this report, we demonstrate that self-assembled Matrigel-free iPSC-derived organoids developed in rotating wall vessels (RWVs) exhibit greater hepatocyte-specific functions than organoids formed on Matrigel. We show that RWVs produce highly functional liver organoids in part by eliminating the need for Matrigel, which has adverse effects on hepatic lineage differentiation. RWV liver organoids sustain durable function over long-term culture and express a range of mature functional genes at levels comparable to adult human liver, while retaining some fetal features. Our results indicate that RWVs provide a simple and high-throughput way to generate Matrigel-free liver organoids suitable for research and clinical applications.
HGF Secreted by Menstrual Blood-Derived Endometrial Stem Cells Ameliorates Non-Alcoholic Fatty Liver Disease Through Downregulation of Hepatic Rnf186
Authors: Du Jiang , Jiang Yan , Liu Xinlei , Ji Xiang , Xu Bo , Zhang Yan , Liu Yanli , Zhang Tao , Lin Juntang 
Published: December 2022

AbstractMesenchymal stem cells (MSCs) have been demonstrated to protect against fatty liver diseases, but the mechanism is still not clear. Menstrual blood-derived endometrial stem cells (MenSCs) are a substantial population of MSCs that can be obtained in a noninvasive manner. In the present study, we investigated the therapeutic effects and underlying mechanisms of MenSC transplantation in mouse models of diet-induced nonalcoholic fatty liver disease (NAFLD). The results revealed that MenSCs markedly promoted hepatic glycogen storage and attenuated lipid accumulation after transplantation. We further identified Rnf186 as a novel regulator involved in MenSC-based therapy for NAFLD mice. Rnf186 deficiency substantially inhibited high-fat diet-induced insulin resistance and abnormal hepatic glucose and lipid metabolism in mice. Mechanistically, Rnf186 regulated glucose and lipid metabolism through the AMPK-mTOR pathway. More importantly, hepatocyte growth factor (HGF) is identified as the key functional cytokine secreted by MenSCs and decreases the expression of hepatic Rnf186. HGF deficient MenSCs cannot attenuate glucose and lipid accumulation after transplantation in NAFLD mice. Collectively, our results provide preliminary evidence for the protective roles of HGF secreted by MenSCs in fatty liver diseases through downregulation of hepatic Rnf186 and suggest that MenSCs or Rnf186 may be an alternative therapeutic approach/target for the treatment of NAFLD.