bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decay, Death, and the Return of Light: The I Ching Yin-Yang Cycle in Philip K. Dick’s The Man in the High Castle
Authors: Lai John T P 
Published: August 2023

Abstract
Through a critical investigation of Philip K. Dick’s best-selling novel The Man in the High Castle, this essay attempts to unearth deeper levels of characterisation and motifs in the novel by discovering the implicit and nuanced symbolisms of the I Ching (Book of Changes) incorporated within it. The article scrutinises the influences of the I Ching upon Dick’s literary creation, particularly how the major themes of decay, death, and the return of light are uniquely depicted in the I Ching cycle of yin and yang, and metaphorically symbolised by several corresponding hexagrams.
Connectivity, Grounding, and Amplification: The Base-Line in Changing and its Functions
Authors: Berengarten Richard 
Published: August 2023

Abstract
This essay is by the author of Changing (CH), ‘a composite poem … based closely on the Chinese Book of Changes’. Here, I explore the multiple functions of the ‘base-line’ in this work. I then discuss Western artists’ emphasis on chance in the I Ching, and argue that this is not the sole quality to be appreciated in the ancient masterpiece. In this context, I apply ideas from quantum theory to suggest that entanglement may be a key to better understanding the I Ching. Since this essay is primarily an exploration of my own compositional procedures as a poet, I implicitly acknowledge the subjective basis of this interpretative enquiry.
Origin of the complex iron line structure and spectral variation in Mrk 766
Authors: Mochizuki Yuto , Mizumoto Misaki , Ebisawa Ken 
Published: August 2023

ABSTRACT
Complex Fe-K emission/absorption line features are commonly observed in the 6–11 keV band from Active Galactic Nuclei (AGN). These features are formed in various physical components surrounding the black holes. The Narrow-Line Seyfert 1 (NLS1) galaxy Mrk 766, in particular, exhibits characteristic blue-shifted Fe-K absorption lines caused by the ultrafast outflow (UFO), and a broad Fe-K emission line, as well as variable absorbers partially covering the X-ray emitting region. We re-analyse the Mrk 766 archival data of XMM-Newton, NuSTAR, and Swift to investigate the origin of the Fe-K line feature and the 0.3–79 keV energy spectral variation. We have found that the spectral variation in ≲10 keV is primarily explained by the variable partial covering of the central X-ray source by multilayer absorbing clouds. The Fe-K line feature consists of the blue-shifted absorption lines due to the UFO, a narrow emission line from the distant material, a broad emission line from the inner-disc reflection, and a slightly broadened weak emission line at around 6.4–6.7 keV whose equivalent width is ∼0.05 keV. The last one is presumably due to the resonance scattering in the UFO out of the line-of-sight, as predicted by a Monte Carlo simulation based on the hydrodynamical UFO modelling. We suggest that the seemingly complex Fe-K line features and the X-ray energy spectra of Mrk 766 are explained by a moderately extended central X-ray source around a Schwarzschild black hole, an optically thick accretion disc with a truncated inner-radius, the UFO, multilayer partial covering clouds, and a torus.
Towards super-resolution simulations of the fuzzy dark matter cosmological model
Authors: Sipp Meris , LaChance Patrick , Croft Rupert , Ni Yueying , Di Matteo Tiziana 
Published: August 2023

ABSTRACT
AI super-resolution, combining deep learning and N-body simulations, has been shown to successfully reproduce the large-scale structure and halo abundances in the Lambda cold dark matter cosmological model. Here, we extend its use to models with a different dark matter content, in this case fuzzy dark matter (FDM), in the approximation that the difference is encoded in the initial power spectrum. We focus on redshift z = 2, with simulations that model smaller scales and lower masses, the latter by two orders of magnitude, than has been done in previous AI super-resolution work. We find that the super-resolution technique can reproduce the power spectrum and halo mass function to within a few per cent of full high-resolution calculations. We also find that halo artefacts, caused by spurious numerical fragmentation of filaments, are equally present in the super-resolution outputs. Although we have not trained the super-resolution algorithm using full quantum pressure FDM simulations, the fact that it performs well at the relevant length and mass scales means that it has promise as a technique that could avoid the very high computational cost of the latter, in some contexts. We conclude that AI super-resolution can become a useful tool to extend the range of dark matter models covered in mock catalogues.
Isolating the linear signal when making redshift space distortion measurements
Authors: Chapman Michael J , Zhai Zhongxu , Percival Will J 
Published: August 2023

ABSTRACT
Constraints on the linear growth rate, fσ8, using small-scale redshift space distortion measurements have a significant statistical advantage over those made on large scales. However, these measurements need to carefully disentangle the linear and non-linear information when interpreting redshift space distortions in terms of fσ8. It is particularly important to do this given that some previous measurements found a significant deviation from the expectation based on the Lambda cold dark matter (ΛCDM) model constrained by Planck cosmic microwave background data. We construct a new emulator-based model for small-scale galaxy clustering with scaling parameters for both the linear and non-linear velocities of galaxies, allowing us to isolate the linear growth rate. We train the emulator using simulations from the AbacusCosmos suite, and apply it to data from the extended Baryon Oscillation Spectroscopic Survey luminous red galaxy sample. We obtain a value of fσ8(z = 0.737) = 0.368 ± 0.041, in 2.3σ tension with the Planck 2018 ΛCDM expectation, and find less dependence on the minimum measurement scale than previous analyses.
Identifying parent bodies of meteorites among near-Earth asteroids
Authors: Carbognani A , Fenucci M 
Published: August 2023

ABSTRACT
Meteorites provide an important source of information about the formation and composition of asteroids, because the level of accuracy of studies and analyses performed in a laboratory cannot be achieved by any ground- or space-based observation. To better understand what asteroid types a meteorite represents, it is crucial to identify the body they originated from. In this paper, we aim to determine possible parent bodies for the known meteorite falls among the known population of near-Earth asteroids (NEAs). By using the similarity criterion DN, based on geocentric quantities, we found 20 possible NEA–meteorite pairs. By performing additional numerical simulations of the backward dynamics, we found that 12 of these pairs may be associated with a possible separation event from the progenitor NEA, while the remaining 8 pairs appear to be ambiguous or random associations. The most interesting are the Pribram and Neuschwanstein meteorites, which are dynamically associated with (482488) 2012 SW20 with a common separation age dating back to about 20–30 kyr ago, and the Motopi Pan meteorite, which has three candidate parent bodies: (454100) 2013 BO73, 2017 MC3, and 2009 FZ4. The average time of separation between our meteorite list and the progenitor body appears to be about 10 kyr, a time consistent with what is expected from the collision frequency of small NEAs. Based on our results, we suggest that about 25 per cent of meteorites do not originate in the main belt, but mainly from little collision events happening between NEAs in the inner Solar system.
EPOCHS VII: discovery of high-redshift (6.5 &lt; z &lt; 12) AGN candidates in JWST ERO and PEARLS data
Authors: Juodžbalis Ignas , Conselice Christopher J , Singh Maitrayee , Adams Nathan , Ormerod Katherine , Harvey Thomas , Austin Duncan , Volonteri Marta , Cohen Seth H , Jansen Rolf A , Summers Jake , Windhorst Rogier A , D’Silva Jordan C J , Koekemoer Anton M , Coe Dan , Driver Simon P , Frye Brenda , Grogin Norman A , Marshall Madeline A , Nonino Mario , Pirzkal Nor , Robotham Aaron , Jr Russell E Ryan , Ortiz III Rafael , Tompkins Scott , Willmer Christopher N A , Yan Haojing 
Published: August 2023

ABSTRACT
We present an analysis of a sample of robust high-redshift galaxies selected from the ‘blank’ fields of the Prime Extragalactic Areas for Reionization Science (PEARLS) survey and Early Release Observations (ERO) data from JWST with the aim of selecting candidate high-redshift active galactic nuclei (AGN). Sources were identified from this parent sample using a threefold selection procedure, which includes spectral energy distribution (SED) fitting to identify sources that are best fitted by AGN SED templates, a further selection based on the relative performance of AGN and non-AGN models, and finally morphological fitting to identify compact sources of emission, resulting in a purity-oriented procedure. Using this procedure, we identify a sample of nine AGN candidates at 6.5 &lt; z &lt; 12, from which we constrain their physical properties as well as measure a lower bound on the AGN fraction in this redshift range of 5 ± 1 per cent. As this is an extreme lower limit due to our focus on purity and our SEDs being calibrated for unobscured Type 1 AGN, this demonstrates that AGN are perhaps quite common at this early epoch. The rest-frame UV colours of our candidate objects suggest that these systems are potentially candidate obese black hole galaxies (OBGs). We also investigate Chandra and VLA maps of these areas from which we calculate detection limits. Of note is a z = 11.9 candidate source exhibiting an abrupt morphological shift in the reddest band as compared to bluer bands, indicating a potential merger or an unusually strong outflow.
A case with febrile attacks and vasculopathy associated with ADA2 and MEFV pathogenic variants
Authors: Parlar Kerem , Tahir Turanli Eda , Nuhoglu Kantarci Eda , Hacioglu Aysa , Kirectepe Aydin Asli , Ayla Ali Yagiz , Voyvoda Umut , Ozdogan Huri , Ugurlu Serdal 
Published: August 2023

ABSTRACT
Deficiency of adenosine deaminase 2 (DADA2), caused by recessive mutations in the adenosine deaminase 2 (ADA2) gene, results in cutaneous or systemic vasculitis with variable clinical manifestations. There is only one other case in literature carrying both ADA2 and MEFV gene pathogenic variants. Here we report the second case that carries both ADA2 and MEFV pathogenic variants, presenting with characteristic phenotypes of both familial Mediterranean fever (FMF) and DADA2. A male patient, currently 29 years old, was initially diagnosed with FMF and developed livedo reticularis and nodular dermal lesions compatible with cutaneous polyarteritis nodosa (PAN) a year after diagnosis. His family history revealed a brother 2 years older than himself who was diagnosed with PAN and died at age 22 because of gut perforation secondary to acute mesenteric ischaemia. ADA2 gene mutation analysis on chromosome 22q11.1 was positive, and the patient responded to colchicine and infliximab.
Impact of menopausal symptoms on work and careers: a cross-sectional study
Authors: O’Neill M T , Jones V , Reid A 
Published: August 2023

Abstract

Background
Women over 50 years are one of the fastest-growing employment groups. Menopausal symptoms can adversely impact quality of life, work performance and attendance; however, few studies look at the impact of individual menopausal symptoms on work and career development.

Aims
To measure the prevalence of menopausal symptoms in employees in a healthcare setting, to assess the impact of individual symptoms on work, attendance and career development and to explore perceptions about workplace supports.

Methods
In this cross-sectional study of Irish hospital workers, menopausal employees were asked about the frequency of 10 menopausal symptoms and the extent to which each symptom impacted them at work. Impacts on performance, attendance and career development were assessed, along with the benefits of workplace support.

Results
Responses from 407 women showed that the most common menopausal symptoms affecting employees greater than 50% of the time while at work were fatigue (54%), difficulty sleeping (47%), poor concentration (44%) and poor memory (40%). Work performance was impacted for 65% of respondents and 18% had taken sick leave. There was a significant association between symptom severity at work and reduced work performance, career development decisions and attendance. Manager awareness about menopause (29%) and flexible working times (29%) were selected as the most important workplace supports.

Conclusions
Female employees are negatively impacted by menopausal symptoms while at work, particularly by psychological and neurocognitive symptoms which were associated with reduced work performance, attendance and career decisions. Manager awareness and flexible schedules were considered the most beneficial workplace supports.
Prognostic Risk Stratification and End-of-Life Care Outcomes in Patients With Metastatic Melanoma Treated With Immune Checkpoint Inhibitors
Authors: Grad Robert N , Jung Seungyeon , Ye Fei , Sun Lili , Johnson Douglas B , Agarwal Rajiv 
Published: August 2023

Abstract

Introduction
The emergence of immune checkpoint inhibitors (ICIs) has improved survival outcomes in patients with metastatic melanoma, while potentially increasing the use of systemic therapy near the end of life (EOL). Yet, less is known on how to facilitate treatment decision making and identify patients who might benefit from early palliative care comanagement.

Materials and Methods
We determined baseline clinical and laboratory factors that are associated with poor prognosis for patients with advanced melanoma treated with ICIs. We subsequently identified prognostic subgroups to evaluate association with EOL outcomes and determine if EOL care varied across prognostic strata.

Results
Our cohort included 398 patients with metastatic melanoma treated with ICIs. Factors associated with overall survival (OS) included: lactate dehydrogenase, neutrophil/lymphocyte ratio, performance status, prior therapies, liver metastases, and lung metastases. Patients were stratified by risk of death using risk scores developed from multivariable analyses. A total of 205 patients died: 45/133 (34%) low-risk, 63/133 (47%) medium-risk, and 97/132 (73%) of high-risk patients. Among those who died, higher risk patients were more likely to receive ICIs within 14, 30, and 90 days of death. We found no association between risk group and hospice referrals or location of death.

Conclusion
Patients with metastatic melanoma at highest risk of death as defined by our model were more likely than lower-risk patients to receive ICIs near the EOL. Prognostic risk stratification may guide early palliative care interventions to appropriately utilize ICIs and optimize EOL care.
Emergence of ultradiscrete states due to phase lock caused by saddle-node bifurcation in discrete limit cycles
Authors: Yamazaki Yoshihiro , Ohmori Shousuke 
Published: August 2023

Abstract
Dynamical properties of limit cycles for a tropically discretized negative feedback model are numerically investigated. This model has a controlling parameter τ, which corresponds to the time interval for the time evolution of phase in the limit cycles. By considering τ as a bifurcation parameter, we find that an ultradiscrete state emerges due to phase lock caused by saddle-node bifurcation. Furthermore, focusing on limit cycles for the max-plus negative feedback model, it is found that the unstable limit cycle in the max-plus model corresponds to the unstable fixed points emerging by the saddle-node bifurcation in the tropically discretized model.
Dusk2Dawn: an EEGLAB plugin for automatic cleaning of whole-night sleep electroencephalogram using Artifact Subspace Reconstruction
Authors: Somervail Richard , Cataldi Jacinthe , Stephan Aurélie M , Siclari Francesca , Iannetti Gian Domenico 
Published: August 2023

Abstract
Whole-night sleep electroencephalogram (EEG) is plagued by several types of large-amplitude artifacts. Common approaches to remove them are fraught with issues: channel interpolation, rejection of noisy intervals, and independent component analysis are time-consuming, rely on subjective user decisions, and result in signal loss. Artifact Subspace Reconstruction (ASR) is an increasingly popular approach to rapidly and automatically clean wake EEG data. Indeed, ASR adaptively removes large-amplitude artifacts regardless of their scalp topography or consistency throughout the recording. This makes ASR, at least in theory, a highly-promising tool to clean whole-night EEG. However, ASR crucially relies on calibration against a subset of relatively clean “baseline” data. This is problematic when the baseline changes substantially over time, as in whole-night EEG data. Here we tackled this issue and, for the first time, validated ASR for cleaning sleep EEG. We demonstrate that ASR applied out-of-the-box, with the parameters recommended for wake EEG, results in the dramatic removal of slow waves. We also provide an appropriate procedure to use ASR for automatic and rapid cleaning of whole-night sleep EEG data or any long EEG recording. Our procedure is freely available in Dusk2Dawn, an open-source plugin for EEGLAB.
Speciation-by-Extinction
Authors: Seeholzer Glenn F , Brumfield Robb T 
Published: August 2023

Abstract
Extinction is a dominant force shaping patterns of biodiversity through time; however its role as a catalyst of speciation through its interaction with intraspecific variation has been overlooked. Here, we synthesize ideas alluded to by Darwin and others into the model of “speciation-by-extinction” in which speciation results from the extinction of intermediate populations within a single geographically variable species. We explore the properties and distinguishing features of speciation-by-extinction with respect to other established speciation models. We demonstrate its plausibility by showing that the experimental extinction of populations within variable species can result in speciation. The prerequisites for speciation-by-extinction, geographically structured intraspecific variation and local extinction, are ubiquitous in nature. We propose that speciation-by-extinction may be a prevalent, but underappreciated, speciation mechanism.
Genome analyses of species A rotavirus isolated from various mammalian hosts in Northern Ireland during 2013−2016
Authors: Lagan Paula , Mooney Mark H , Lemon Ken 
Published: August 2023

Abstract
Rotavirus group A (RVA) is the most important cause of acute diarrhoea and severe dehydration in young mammals. Infection in livestock is associated with significant mortality and economic losses and, together with wildlife reservoirs, acts as a potential source of zoonotic transmission. Therefore, molecular surveillance of circulating RVA strains in animal species is necessary to assess the risks posed to humans and their livestock. An RVA molecular epidemiological surveillance study on clinically diseased livestock species revealed high prevalence in cattle and pigs (31 per cent and 18 per cent, respectively) with significant phylogenetic diversity including a novel and divergent ovine artiodactyl DS-1-like constellation G10-P[15]-I2-R2-C2-M2-A11-N2-T6-E2-H3. An RVA gene reassortment occurred in an RVA asymptomatic pig and identified as a G5-P[13] strain, and a non-structural protein (NSP)2 gene had intergenomically reassorted with a human RVA strain (reverse zoonosis) and possessed a novel NSP4 enterotoxin E9 which may relate to the asymptomatic RVA infection. Analysis of a novel sheep G10-P[15] strain viral protein 4 gene imparts a putative homologous intergenic and interspecies recombination event, subsequently creating the new P[15] divergent lineage. While surveillance across a wider range of wildlife and exotic species identified generally negative or low prevalence, a novel RVA interspecies transmission in a non-indigenous pudu deer (zoo origin) with the constellation of G6-P[11]12-R2-C2-M2-A3-N2-T6-E2-H3 was detected at a viral load of 11.1 log10 copies/gram. The detection of novel emerging strains, interspecies reassortment, interspecies infection, and recombination of RVA circulating in animal livestock and wildlife reservoirs is of paramount importance to the RVA epidemiology and evolution for the One Health approach and post-human vaccine introduction era where highly virulent animal RVA genotypes have the potential to be zoonotically transmitted.
Study of Infections in Breast Augmentation Surgery with Implants in 9,691 Patients over 5 Years
Authors: Mesa Felipe , Cataño Sebastian , Tuberquia Oscar 
Published: August 2023

Background:
This study presents a review of a single retrospective cohort of patients who underwent surgery for breast augmentation with implants, during a period of 5 years, aged 17–60 years (mean 32 years), in a single institution, IQ Interquirofanos, a private clinic in the city of Medellín, Colombia.

Method:
A single retrospective cohort study was carried out, in which the database of patients who underwent breast augmentation with implants during 5 years was analyzed.

Results:
In this period of time, 9,691 female patients and a total of 19,382 breast implants implanted by 66 plastic surgeons underwent breast augmentation surgery. All the breast prostheses used were round, made of silicone gel in all cases and textured in most of them. 37 patients presented infection at the surgical site, 33 were unilateral and four bilateral, with an incidence of 0.38% per patient. The form of presentation was cellulitis in 46% of the cases, followed by seroma and hematoma in 25%. It was found that there is no difference in the incidence of infection between patients with breast augmentation for the first time and implant replacement due to different causes (OR 1.25, 95% CI 0.66–2.3, P = 0.49). One of the surgeons was associated with 37.8% of the infections and was found to be an asymptomatic carrier of Staphylococcus aureus, requiring medical treatment. The relationship of the infection with the treating surgeons was also analyzed and it was found that there is an association between these two variables. The infection appeared in the first 2 weeks after surgery in 92.7% of the cases. The main isolated germ was Staphylococcus aureus, followed by Pseudomona aeruginosa, Staphylococcus epidermidis, Serratia marcescens, Candida parapsilosis, Enterobacter cloacae, and a patient with Mycobacterium fortuitum in both breasts. Of the 37 patients with infection, six breast implants were required to be explanted in five patients, who were repositioned 3–6 months later without complications.

Conclusions:
Incidence of infection in augmentation mammoplasty with implants was 0.38% in patients infected in one or both breasts, during 5 years. There is a relationship between the presence of breast infection and the surgeon who performed the intervention. The most frequent germs found in breast implant infections continue to be Staphylococcus aureus followed by Pseudomonas aeruginosa.