bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sabbath and Sunday: The meaning of the day of rest in the ancient church – A hope for the future?
Authors: Vaida Cristian 
Published: February 2023

The Sabbath is part of Jewish tradition. In Christianity it has taken on a new meaning. Both faiths saw it as a gift from God, a tool to affirm one’s spiritual creed and identity, and a way to maintain a distinct faith identity. The secularism of contemporary society has resulted in a misinterpretation of the purpose of Sunday rest and a disregard for the spiritual aspects that the Sunday celebration involves. A false perception of Sunday rest has emerged in modern times: It is not perceived as a divine gift that enables a spiritual ministry, which leads to resistance and opposition to the restless anxiety of the consumerist world and serves as an alternative to advertising’s demanding presence in this world. This rest, as a gift from God, has been one of the most fundamental defining features of man’s connection with God throughout history. Since Christian antiquity, there has been substantial debate over how to observe this tremendous gift of rest. Rest was valued as a gift in the Jewish culture in a specific way that included defining the identity of the chosen people. Later, in the Christian tradition, it was connected to the celebration of Christ’s Resurrection and the spiritual healing He provided to the world. There has been much debate on the continuity and discontinuity between the Jewish Sabbath and the Christian Sunday, as well as on how the transition from the Sabbath to the Sunday celebration came about. The two qualities of the Jewish Sabbath – a day of rest and a day of religious celebration – have been transferred to the Christian Sunday but in a radically different context.Contribution: By analysing early Christian literature, this study aims to investigate how the concept of Sabbath rest was taken up and reconstructed in Christianity in the celebration of Sunday, and how spiritual work was a constant in the life of Christian communities up until the 4th century, when Sunday rest was established by law. Contrary to Rordorf’s opinions, this article aims to show that Christians, despite being physically obligated to work on Sundays, tacitly observed this day as a day of resurrection, emphasising the spiritual work of the virtues as their vehicle towards their entrance into the rest in God, even before Sunday became socially established as a day of rest (Heb 4:1–11). This study intends to show that this unique vision of the Sunday rest of the early church can be an element of resistance and an alternative to the demanding stress and restless anxiety of modern society.
Alexis O-ring wound retractor versus traditional metal retractors for the prevention of postcaesarean surgical site infections
Authors: Mothiba Marabe S. , Tshepuwane Tshimane C. , Adefolalu Adegoke O. , Monokoane Tshweu S. 
Published: February 2023

Background: Postcaesarean surgical site infections (SSI) remain a burden globally. The Alexis® O C-Section Retractor, a plastic sheath retractor known to have decreased incidence of SSIs in gastrointestinal surgery, is yet to have its efficacy established during caesarean section (CS). This study aimed to compare the differences in the rate of postcaesarean surgical wound site infections between the Alexis® retractor and traditional metal retractors during CS at a large tertiary hospital in Pretoria.Methods: Pregnant women scheduled for elective CS were prospectively randomised to either the Alexis® retractor group or the traditional metal retractor group at a tertiary hospital in Pretoria between August 2015 and July 2016. The defined primary outcome was development of SSI, and secondary outcomes comprised patients’ peri-operative parameters. All participants’ wound sites were observed in the hospital for 3 days before discharge and again at 30 days postpartum. Data were analysed using SPSS version 25 with p 0.05 considered significant.Results: A total of 207 participants were involved, Alexis® (n = 102) and metal retractors (n = 105). None of the participants developed postsurgical site wound infection after 30 days, and there were no differences in time to delivery, total operative time, estimated blood loss or postoperative pain between the two arms of study.Conclusion: The study found no difference in participants’ outcomes using the Alexis® retractor in comparison with the traditional metal wound retractors. We suggest that the use of Alexis® retractor be at the surgeon’s discretion and its routine use not advised for now.Contribution: This research being the first of its kind in South Africa in which patients’ clinical outcomes were compared post caesarean section from Alexis’s plastic sheath group and metal retractors group in an attempt to proffer solution to the high burden of SSI. Although no difference was seen at this point, the research was pragmatic, as it was carried out in a setting with high burden of SSI. The study is going to serve as a baseline against which studies carried out in future can be compared.
Assessment of Pulmonary Hypertension in Chronic Kidney Disease Patients using Doppler Echocardiography
Authors: Gaur Jyoti , Singh Rakesh Kumar , Kulkarni Chaitanya , Dube Simmi 
Published: February 2023

Background:
The incidence of chronic kidney disease (CKD) is increasing globally and is associated with significant morbidity and mortality related to the cardiovascular system. There is limited data on pulmonary hypertension (PH) in CKD patients, especially from developing and underdeveloped countries. PH leads to hypoxia which is a significant cause of dyspnea in CKD patients with or without pulmonary edema. Hence, we planned this study to assess the PH in CKD patients using two-dimensional (2D) color Doppler echocardiography.

Materials and Methods:
This is an observational cross-sectional study. A total of 100 CKD patients on hemodialysis or conservative management were enrolled in the study. Following the collection of demographic data, and routine/specific investigations, these patients were assessed for PH using 2D color Doppler echocardiography.

Results:
PH was found in 47% of patients with CKD. Left ventricular (LV) hypertrophy, systolic and diastolic dysfunction, dilated right atrium/right ventricular and left atrial/LV chambers, and valvular hypertrophy were other echocardiography findings recorded in these patients. Low hemoglobin levels, high urea/creatinine levels, and duration of hemodialysis in CKD patients were found to be significantly associated with the presence of PH.

Conclusion:
The majority of CKD patients have PH at various stages of disease-causing unexplained dyspnea in these patients. PH is common in end-stage CKD as compared to patients with a less severe stage of CKD. Hence, CKD patients should be evaluated for PH, especially in the presence of intractable dyspnea.
Myocardial Bridging in Cases of Sudden Death and its Association with Clinicopathologic Characteristics
Authors: Sylvia Mary Theresa , Soundharia R , Bhat Ramachandra V. , Marak Fremingston 
Published: February 2023

Background:
Myocardial bridging (MB) is the course of the epicardial segment of a coronary artery within the myocardium. The systolic compression of this segment called the tunneled segment may lead to alterations in blood flow to the heart. We have studied the gross and microscopic features of MB in cases of sudden cardiac death and analyzed its characteristics and whether there is any association with other clinicopathological characteristics which may help us to understand the pathogenesis and risk stratification.

Materials and Methods:
This is a retrospective descriptive study of 132 postmortem heart specimens of sudden cardiac death. The coronary arteries were dissected, and MB and its characteristics were studied. Statistical analysis was performed using the Chi-square and Fisher's exact tests (P < 0.05 significant).

Results:
MB was present in 28 cases (21.2%), with a mean age of 49.5 years and male:female ratio of 27:1. MB was seen in the left anterior descending artery in 86.2% of cases, the right coronary artery in 10%, and left circumflex artery in 3.5% of cases. Atherosclerosis was seen in the segment proximal to the tunneling in 89.2% of cases leading to infarction in four cases. Left ventricular hypertrophy (LVH) was significantly associated with MB cases (19/68%) (P < 0.05).

Conclusion:
MB causes turbulence of blood in the proximal segment leading to coronary atherosclerosis, thereby predisposing the heart to ischemic changes and LVH and may lead to infarction in a few cases.
Left Ventricular Global Longitudinal Strain by Speckle Tracking Echocardiography as a Noninvasive Predictor in Evaluation of Myocardial Infarction
Authors: Kumar K. P. , Piedade Joel Quadros , Malali Venkatesh , Hegde Srinidhi 
Published: February 2023

Background:
Coronary artery disease (CAD) has assumed epidemic proportions in the world. Accurate risk stratification and early invasive management when indicated can reduce morbidity and mortality substantially. The study aims to correlate left ventricular (LV) function assessed by global longitudinal strain (GLS) with the extent of CAD in patients with myocardial infarction (MI).

Methods:
The study was conducted in a tertiary care hospital in Southern India. A total of 105 patients admitted with a diagnosis of non ST-elevation MI were included. All patients had a detailed echocardiogram with the evaluation of LV GLS by two-dimensional speckle tracking echocardiography and ejection fraction by Simpson's method. Coronary angiogram was also done in all patients to study the coronary anatomy and the relation between CAD and LV GLS.

Results:
The mean age of study population was 53.9 years. Echocardiographic study revealed mean LV ejection fraction (LVEF) was 48.16 + 12.27. The mean LVEF in patients with single-vessel disease was 50.11 + 11.62; with two-vessel disease, it was 51.81 + 10.34, and in patients with triple-vessel disease, it was 41.5 + 11.8. The mean GLS in the abovementioned groups was − 15.6 + 3.33, −13.5 + 3.2, and − 11.02 + 4.14, respectively. The follow-up of patients also showed a considerably lower GLS in patients who suffered higher morbidity and mortality.

Conclusion:
LV GLS is a good noninvasive predictor of the burden of CAD on the angiogram and also a predictor of future cardiovascular events and mortality.
Understanding the Status of the Egyptian Coronary Lesions
Authors: El-Dosouky Ibtesam Ibrahim , Nashy Baher Nabil , Abomandour Hala Gouda 
Published: February 2023

Background:
High-probability zones of coronary thrombosis may exist along the coronary tree. We aimed to determine the nature and distribution of significant coronary lesions among our patients.

Methods:
This study included 529 patients, for whom coronary angiography was done for suspected or proved coronary artery disease (CAD), they were divided into three groups according to the distribution of the coronary lesions: left anterior descending (LAD) group (n = 305) with significant LAD lesion, left circumflex (LCx) group (n = 148) with significant LCx lesion and right coronary artery (RCA) group (n = 181) with significant RCA lesion.

Results:
One hundred and sixty-nine (31.9%) had nonsignificant lesion, 166 (31.4%) had single-vessel disease, with significantly higher incidence of significant LAD lesion 305 (57.5%) which were proximal 52.4%, LAD lesions were more prone to be the culprit vessel 47.5%, LCx was the least vessel with significant lesion 148 (27.9%), and the least to be prone as a culprit 21.1%. Proximal culprit LAD 63.5% and RCA 55.6% had significantly higher incidence, mid culprit LC× 53.9% had significantly higher incidence. ST-elevation acute coronary syndrome (STE-ACS) was significantly more prevalent in culprit LAD 76.7%. Non-STE-ACS was significantly more prevalent in culprit LC× 56.5% and RCA 55.6%.

Conclusion:
LAD tends to carry more than one culprit lesion, more to be proximal. Risk factors responsible for instability and sheer stress (uncontrolled diabetes mellitus, uncontrolled hypertension, heavy smoking) were more prevalent between patients with LCx as a culprit followed by RCA in Egyptian; this may throw the light on the need for aggressive control of these risk factors to reduce vulnerability in these patients.
Qt-Dispersion and Major Adverse Cardiovascular Events Prediction After Percutaneous Coronary Intervention in Patients with Type 2 Diabetes Mellitus
Authors: Wageeh Shaimaa , EL-Dosouky Ibtesam , ELShabrawy Arafa M. , Omar Rasha E H , Zein Shimaa G 
Published: February 2023

Objectives:
The objective of this study investigated the relation between QT-dispersion (QTd) and both number of coronary artery disease and major adverse cardiovascular events (MACEs) among patients with type 2 diabetes after elective percutaneous coronary intervention (PCI).

Methods:
One hundred ischemic heart disease patients undergoing elective coronary angioplasty were included; 49 patients with diabetes (group I) and 51 patients without diabetes mellitus (group II). Based on the QTd parameter after PCI, both groups were subdivided into tertiles. Angiographic, electrocardiographic parameters, and MACE were compared.

Results:
Both QTd after PCI and delta QTd were correlated to the number of diseased coronary arteries and MACE in patients with diabetes compared to patients without diabetes. QTd was longer in patients with diabetes developing MACE than those without MACE (r = −0.31, P = 0.04).

Conclusion:
QTd after PCI and delta QTd are the independent predictors of MACE in patients with type 2 diabetes.
Incidence, Management Patterns, and Outcomes of Cardiovascular Implantable Electronic Device-Related Infection – A Retrospective Registry-Based Analysis
Authors: Goel Pravin K. , Rajput Paritosh , Sahu Ankit Kumar , Khanna Roopali , Garg Naveen , Tewari Satyendra , Kumar Sudeep , Kapoor Aditya 
Published: February 2023

Introduction:
Cardiovascular implantable electronic device (CIED) infection contributes to a significant clinical and financial burden. We sought to assess CIED postimplant infection rates and the effect of different treatment modalities on reinfection over a long-term follow-up.

Methods:
We retrospectively analyzed CIED recipients presenting with complications during 2010–2019 at our center. Data related to the different management modalities used as per the discretion of treating physician, were collected and patients were followed up telephonically.

Results:
A total of 3394 patients underwent CIED implantation of which 122 (3.5%) patients developing complications were included in the study. Mean age of the patients was 66.4 ± 12.5 years. Single-chamber ventricular pacing (VVI), dual-chamber (DDD) pacing, and biventricular pacing were seen in 68 (56.2%), 51 (41%), and 3 (2.8%) patients, respectively. CIED infection was seen in 61 patients (1.8%). Strategies used for CIED infection management included: new device implantation on contralateral side (n = 34; 55.7%), old device repositioning on same side (n = 14; 22.8%), antibiotic therapy alone (n = 5; 8.5%), resterilized device implantation on contralateral side (n = 3; 4.9%), epicardial lead placement (n = 3; 4.9%), and permanent device removal (n = 2; 3.3%). The CIED reinfection rates for the above strategies were 2.9%, 71.4%, 80%, 100%, 0% and 0%, respectively.

Conclusion:
Multiple strategies are being used in real-world practice for the management of CIED infection. Previously advocated strategy of reimplanting resterilized CIED is associated with high recurrence rates. The best practice still remains to implant a new device on the contralateral side post extraction of infected hardware.
Newer Oral Anticoagulants in Venous Thromboembolism
Authors: Modi Sunil , Modi Ranjan 
Published: February 2023

Abstract
Venous thromboembolism (VTE) is an important medical condition for morbidity and mortality. Adequate anticoagulant treatment is necessary to reduce short- and long-term VTE related conditions. In the past low molecular weight heparin (LMWH) and Vitamin K antagonists (VKAs) have been the mainstay of anticoagulation therapy for VTE patients. The patients require frequent monitoring with INR to keep balance between effectiveness and safety in clinical practice. NOACs have been the main stay of treatment in conditions requiring effective anticoagulation. They may prove to do the same in VTE. This article analyses, the present literature on use of NOACs in VTE.
An Interesting Case of Unusual Cause of Refractory Ventricular Tachycardia in a Chronic Kidney Disease Patient
Authors: Tumkur Ashwin , Sudhakar G. , Goura Prakash 
Published: February 2023

Abstract
Refractory ventricular tachycardia (RVT) has been a life-threatening form of arrhythmias. There are many causes reported in literature that are found to trigger RVT. Here, we report a rare cause of RVT. A gentleman under maintenance hemodialysis since 1 year was emplaced with permacatheter since then. He presented with signs and symptoms of RVT, on evaluation, it was found that RVT was caused due to broken permacatheter fragment that was embolized into the right ventricle. It was successfully retrieved through snare loop as an emergency and the RVT was then reverted to normal rhythm. Therefore, in patients undergoing hemodialysis or under treatment with such access devices symptoms of chest pain, irregular heart rhythms or complications like retained catheter must be considered as a part of differential diagnosis, even when substantial time has elapsed after initial catheter access emplacement.
Impact of Low Early High-Density Lipoprotein Cholesterol on Inhospital Outcome and Short-Term Prognosis in Patients with Acute Coronary Syndrome
Authors: Elkholy Tarek E. , Saeed Ekram S. , Omar Mahmoud A. Abo , El-barbary Yasser H. 
Published: February 2023

Abstract

Background:
Acute coronary syndrome (ACS) is a cardiac emergency and constitutes a major burden globally. Association between serum lipid and ACS is established many years ago. Our study tried to have more information about the impact of high-density lipoprotein cholesterol (HDL-C) on inhospital outcome and short-term prognosis of patients with ACS.

Materials and Methods:
The study was a prospective comparative study. Clinical and chemical and interventional evaluation was done in hospital settings. A total number of 50 patients were included in the study and divided into two groups. Patients with low HDL-C level were in Group I and patients with normal HDL-C were in Group II.

Results:
Group I populations had more inhospital complications than Group II represented in acute heart failure (48% vs. 13%), cardiogenic shock (40% vs. 6%), complex coronary lesions (57% vs. 20%), and prolonged hospital stay (54% vs. 20%). A statistical significance was found regarding these variables (P < 0.05). Regarding the outcome after 1 month, it is observed that patients of Group I significantly experienced heart failure (59.38% vs. 21.43%) and worsening angina (62.5% vs. 28.57%) with a statistically significant difference. In contrast, there is no statistically significant difference regarding myocardial infarction, new cerebrovascular events, shock, and mortality.

Conclusion:
The study showed a strong association of HDL-C level with inhospital adverse events of ACS patients in addition to short-term adverse events. Complications of ACS were more in patients with low HDL-C level.
Outcomes of Percutaneous Coronary Intervention in the Young
Authors: Lakshmi Vanaparty Satya Bharathi , Nemani Lalita , Sheik Jahangir Basha 
Published: February 2023

Background:
The incidence of coronary artery disease in the young is constantly rising. Understanding the outcomes of percutaneous coronary intervention (PCI) in young adults is necessary. This study aims to assess the procedural outcomes, inhospital and 1 year clinical outcomes of PCI in the young (<40-year-old).

Methods:
This is a prospective, observational study carried out in the Department of Cardiology at Nizam's Institute of Medical Sciences. The study included all subjects ≤40 years of age and has undergone PCI from January 1, 2019 to December 31, 2019 in our institute.

Results:
The study included 207 patients with a mean age of 36.01 ± 3.72 years and 72.46% males. Acute coronary syndrome was seen in 79.2% patients with ST elevation myocardial infarction (STEMI) being the most common. The median time interval of presentation in STEMI was 12–48 h (73%). Major adverse cardiac events (MACE) over 1-year were seen in 3.8% patients. Severe left ventricular (LV) dysfunction at presentation was an independent factor for acute (P = 0.04) and 1-year mortality (P = 0.0058). It was also associated with angina and chronic heart failure (CHF). Slow flow was significantly associated with mortality (P = 0.0254) and adverse 1 year outcomes. It was significantly associated with persistent LV dysfunction and recurrent CHF.

Conclusion:
Success rate after PCI is high in the young. 1 year outcome is very good with low mortality and MACE events. Severe LV dysfunction and slow flow are independent predictors of poor prognosis at 1 year.
Knowledge, attitude, and practice of injury prevention exercise programmes and the FIFA 11+ among Malaysian elite soccer league coaches
Authors: Hamdan Muhammad , Sharir Raihana , Kian Yeo Wee , Dzulfakar Radin Rafeeuddin Radin , Richard Helber , Raja Azidin Raja Mohammed Firhad 
Published: February 2023

Background:
A number of injury prevention programmes have been introduced in soccer. However, the familiarity and utility of these programmes by coaches in Malaysia is yet to be determined. Aim and Objectives: This study aimed to record the knowledge, attitude and practice of injury prevention exercise programmes (IPEPs), specifically the FIFA 11+, amongst coaches of elite league teams in Malaysia.

Materials and Methods:
Active coaches from four elite soccer leagues (Super League, Premier League, President's Cup and Youth Cup) in Malaysia were invited to participate. Thirty-three (n = 33) responses were returned.

Results:
Most respondents (87.9%) agree that soccer players are at high risk of lower-limb injury, and that it could have adverse effects on teams' and players' performances, careers and quality of life. More than two-thirds (71.9%) of respondents were optimistic about lower-limb soccer injury prophylaxis, however, familiarity toward the FIFA 11+ was considerably low, thus its practice is relatively low. Most respondents familiar to the programme believe that improvements could be introduced to suit their teams better or develop an own version of the FIFA 11+ specifically tailored for their teams. Having the need for equipment and lack of supervision may hinder IPEP maintenance in a team.

Conclusion:
Injury prevention programmes need early implementation and progressive variation for ongoing practice. Clearly, no IPEP may serve as the perfect 'one-programme-fits-all' injury prevention measure. This study may provide some insight for practitioners and soccer club organizers to develop future IPEPs and exercise better programme delivery amongst professional soccer teams.