bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of different origin impact on zoosporangium viability of potato wart causative agents Synchytrium endobioticum (Schilbersky) Percival
Authors: Zelya A. , Kuchnir O. , Zelya G. , Vovk M. , Makar T. 
Published: April 2023

Goal. To determine the technical efficiency of chemical, biological and new synthesized drugs in controlling the causative agent of potato cancer.
Methods. For research, soil samples were used, taken from the foci of the causative agent of cancer before and after treatment with the following drugs: chemical — Emesto Quantum, 273.5 FS (clothianidin, 207 g/l + penflufen, 66.5 g/l), Consento 450 SC (phenamidon, 75 g/l, + propamocarb hydrochloride, 375 g/l); biological — Fitodoktor, p. (Bacillus subtilis bacteria, IMV B-7100 (26D), titer 5 ќ 10 9/g of the drug), Planryz, genus. (Pseudomonas fluorescens bacteria, piece AP 33, titer 3.0 ќ 10 9 cm3); synthesized — onium derivatives of 4-aryl-5-methoxycarbonyl-3.4-dihydropyrimidin-2-one. Soil samples for the detection of pathogens from one soil sample were taken by standard methods according to EPPO Standards PM 7/28 (2), with the geolocation of the sampling points recorded by the Garmin eTrex Legend GPS navigator. Zoosporangia of the causative agent of cancer were isolated by flotation in the «RUTA» device in sodium iodide solution. The viability of zoosporangia was determined using Coomassie blue G-250 solution. The effectiveness of the drugs was determined according to the methods of testing and application of pesticides (Trybel S. and others).
Results. For 2019—2021, the effect of chemical and biological preparations on the viability of zoosporangia of the causative agent of potato cancer was investigated. As a result of treatment with the synthesized chemical onium derivative 4-aryl-5-methoxycarbonyl-3.4-dihydropyrimidin-2-one, the efficiency was 71.4%; Emesto Quantum, 273.5 FS — 48.4%; Consento 450 SC — 82.3%. As a result of the action of the biological drug FitoDoctor, the effectiveness was 25.8%; Planriz, genus. — 32.3%.
Conclusions. To protect potatoes from the disease, it is recommended to use biological and onium derivatives of 4-aryl-5-methoxycarbonyl-3,4-dihydropyrimidin-2-one, which will allow to reduce the number of viable zoosporangia of the pathogen in the soil in 3—5 years and thereby reduce the pesticide press in potato growing and improve the ecological condition of the environment.
Soil herbicides in sunflower crops in the Eastern Forest-Steppe of Ukraine
Authors: Zuza V. , Shevchenko M. , Hutianskyi R. , Kuzmenko N. 
Published: April 2023

Goal. To determine the influence of soil herbicides with different active substances on crop weediness and sunflower seed yield in the conditions of the Eastern Forest Steppe of Ukraine.
Methods. Field, measuring and weighting, and statistical.
Results. In 2019, with 13 mm of precipitation in the first period after applying soil herbicides, the effectiveness of herbicides in reducing the number and raw mass of weeds in sunflower crops was 60% and 45%, respectively, and in 2021 with 81 mm of precipitation, it was 89% and 95%. In 2021, there was phytotoxic suppression of culture plants by Kharnes, e.c. (acetochlor, 900 g/l), 2.5 l/ha. Despite this, Kharnes was the most effective in controlling the total number of weeds (91% and 96% for the first and second counts, respectively) and their raw mass (95%). Other preparations provided the following indicators: Proponit 720, EC (propisochlor, 720 g/l), 3.0 l/ ha (by quantity — 84% and 90%, by weight — 84%); Selefit, SC (promethrin, 500 g/l), 4.0 l/ha (by quantity — 79% and 81%, by weight — 70%); Prymekstra TZ Hold 500 SC (S-metolachlor, 312.5 g/l + terbuthylazine, 187.5 g/l), 4.5 l/ha (by quantity — 68% and 73%, by weight — 66%); Stomp 330, e.c. (pendimethalin, 330 g/l), 5.0 l/ha (by quantity — 51% and 63%, by weight — 60%); Komandyr, EC (clomazon, 480 g/l), 0.15 l/ha (26% and 52% by quantity, 37% by weight). Ambrosia artemisiifolia L. was resistant to the above soil herbicides. It was established that sunflower is a powerful competitor in agrophytocenosis. Its share in the total raw mass of agrophytocenosis, depending on the period of accounting, was from 65.8 to 82.0%, and in dry mass — from 61.8 to 80.2%. In addition, it was established that losses of the sunflower crop from weeds coincide with the specific share of weeds in the total mass of the agrophytocenosis. Soil herbicides provided the following increases in the yield of sunflower seeds (t/ha): Kharnes — 0.53; Proponit 720 — 0.46; Stomp 330 — 0.44; Prymekstra TZ Hold 500 SC and Selefit — 0.39; Komandyr — 0.17. It was found that sunflower was the most tolerant to Stomp 330, and the least — to Komandyr.
Conclusions. In terms of the level of weed death in sunflower crops and the increase in the yield of its seeds, Kharnes was the best among soil herbicides, and Komandyr was the worst.
A Study to Assess the Effect of Health Teaching on Knowledge Regarding COVID 19 among Care Taker in Selected Hospital
Authors: - Ms.Heera Bhalerao 
Published: April 2023

Background: Covid in children-s the number of people across India testing positive for the COVID-19 has increased, the number of children contracting the virus has also increased. However, we have not seen a sudden spike in the overall percentage of children affected by COVID-19 in India.
One feature of the new wave is that now entire households are becoming infected with the virus, more so than in the first wave.
We still need to be cautious and continue to follow COVID-19 appropriate behaviours strictly. It’s also important to be aware how children are feeling each day.
Objective:
•	To determine the care taker knowledge regarding COVID 19
•	To identify the effect to care taker knowledge regarding COVID 19
•	To find an association of Care taker knowledge with selected demographic variables.
Material and Method: The study is an evaluative study with pre experimental one group pre and post test research design. 60 samples were selected for the study by Non-probability purposive sampling technique. The pre-test was done first and then health teaching was given to the care taker. Then post-test was provided to group after a gap of 7 days for the knowledge assessment. Data was analyzed by using descriptive and inferential statistics.
Result: The findings of the study revealed that, pre-test scores hows43.33%ofthecare taker , 28.33% had very poor knowledge and 28.34% had average knowledge regarding COVID 19. After health teaching is provided, post-test scores showed 90% mothers of under-five children had good knowledge and 40% had average knowledge of dehydration. This indicates that, there is a remarkable improvement in the knowledge among mothers regarding assessment and management of dehydration in children.
Conclusion: As the current emphasis of health care nowadays is on health and wellness of children, mothers of under-five children to know about the Precisions in the hospital and management. Hence, care taker require continuous and adequate knowledge about COVID 19.One method that can help in improving their knowledge by conducting health teaching. As the study itself was shown, health teaching is an effective tool that can be adopted as one of the method in improvising the knowledge of Care take toward providing adequate Precaution. of evidence- based practice guidelines Social distance and using face mask and sanitizer.
Evaluating analytical performance and characterization of silver-based SERS substrate fabricated by 3D printed microfluidic droplet generation
Authors: Lee Yong-Ill , Sonexai Phommachith , Nguyen Minh Van , Huy Bui The 
Published: April 2023

The detection of harmful chemicals in the environment and food safety is a crucial requirement. While traditional techniques such as GC-MS and HPLC have provided high sensitivity, they are expensive, time-consuming, and require skilled labor. On the other hand, Surface-enhanced Raman spectroscopy is a powerful analytical tool for detecting ultra-low concentrations of chemical compounds and biomolecules. We present a reproducible method for producing uniform-sized Ag nanoparticles, which can be used to create highly sensitive SERS substrates. A microfluidic device was employed to minimize the precursor reagents within the droplets, resulting in uniform shape and size Ag nanoparticles. The study investigates the effects of various synthesis conditions on the size distribution, dispersity, and localized surface plasmon resonance wavelength of the Ag nanoparticles. To create the SERS substrate, the as-synthesized Ag nanoparticles were assembled into a monolayer on a liquid/air interface and deposited onto a porous silicon array prepared through a metal-assisted chemical etching approach. By using the developed microfluidic, the enhancement factor of the Raman signal for rhodamine B (at 10-9 M) and melamine (at 10-7 M) was calculated to be 8.59 ´ 106 and 8.21 ´ 103, respectively. The detection limits for rhodamine B and melamine were estimated to be 1.94 × 10-10 M and 2.8 × 10-8 M with an RSD ~ 3.4% and 4.6%, respectively. The developed SERS substrate exhibits exceptional analytical performance and has the potential to be a valuable analytical tool for monitoring environmental contaminants.
L’arrondissement de Nantua retrouve sa sous-préfète
Authors: Balu Danielle 
Published: April 2023

Un seul sous-préfet était en charge des deux arrondissements de Nantua et de Gex (département de l’Ain) depuis 2016, date à laquelle les sous-préfectures ont été « jumelées ». Six ans plus tard, le Président de la République décide, dans le cadre de la réouverture de sous-préfectures, de mettre fin à ce jumelage. Le 17 octobre 2022, Danielle Balu est nommée sous-préfète de Nantua.
La réorganisation des services des finances publiques sur les territoires
Authors: Fournel Jérôme 
Published: April 2023

Depuis juin 2019, la direction générale des Finances publiques a entrepris un vaste projet de réorganisation de son réseau territorial, fondé sur une approche concertée avec tous les acteurs (agents des Finances publiques, organisations, élus locaux et nationaux), ainsi que sur les besoins des territoires, pour tenir compte de la demande de nos concitoyens de pouvoir bénéficier d’un service public proche d’eux et plus efficient. Nous sommes désormais présents dans 2 536 France Services labellisées, situées à moins de 30 minutes du domicile de l’usager (dont certaines itinérantes). Nous assurons également 469 permanences en mairies et 81 permanences dans d’autres tiers lieux. La satisfaction des usagers y est au rendez-vous puisque 95% d’entre eux indiquent que les réponses obtenues en France services sont adaptées à leur demande et 93% se disent satisfaits du service que leur rendent nos agents. 2 975 communes disposent d’un accueil « Finances publiques », soit une augmentation de 50% par rapport au 1er janvier 2019. L’objectif d’une augmentation de 30% du nombre de communes par rapport à la situation de 2019 est donc d’ores et déjà largement dépassé.
L’école rurale et la proximité
Authors: N’Gahane Pierre 
Published: April 2023

L’école en milieu rural est souvent un point de repère au même titre que la mairie de la commune ou même la brigade territoriale de gendarmerie. Elle fait partie des services publics de proximité auxquels nos concitoyens sont très fortement attachés. Elle participe à la vie du territoire. Elle permet de fixer les familles dans les villages, souvent même à en faire venir de nouvelles. Dans une académie comme celle de Dijon, davantage rurale, 55,6% d’écoles publiques ont au plus trois classes contre 33% au niveau national ! C’est un engagement pour l’égalité des chances de la République, même si des enjeux pédagogiques voire éducatifs peuvent être convoqués à certains moments.
Pour une révolution copernicienne
Authors: Abrard Christian 
Published: April 2023

En lançant en septembre 2021 le plan “Marseille en grand”, le président de la République a souhaité qu’une nouvelle démarche, partant des projets des écoles volontaires, soit mise en œuvre : une méthode nouvelle qui parte du bas. En neuf mois, une relation de confiance inédite s’est nouée entre les équipes pédagogiques engagées et l’administration de l’Éducation nationale, permettant la mise en œuvre et le développement des projets. Le 2 juin 2022, le Président annonçait de Marseille la généralisation à l’échelle du pays. Il en précisait les contours lors de la réunion de rentrée des plus hauts cadres de l’Éducation nationale, à La Sorbonne, appelant à une « révolution copernicienne ». Depuis l’automne, les établissements volontaires font, dans le cadre du CNR Éducation, remonter leurs projets. Succès quantitatif, l’opération ne pourra se consolider et s’inscrire dans le temps que si un accompagnement de chaque projet est mis en œuvre dans tous les territoires. À cet effet le système administratif va devoir s’adapter et se réinventer. Mais, au-delà de la démarche entreprise dans l’Éducation nationale, c’est bien l’ensemble de la fonction publique qui demande une réforme systémique, une révolution copernicienne.
De la définition d’une stratégie territoriale multi-acteurs à sa mise en action : analyse d’un échec partiel
Authors: Evon Juliette 
Published: April 2023

Face à une fragilité territoriale, notre recherche pose la question suivante : quels sont les impacts, les apports et les limites pour le territoire et ses acteurs d’un processus de définition d’une stratégie territoriale et de sa mise en action au travers d’un projet territorial sectoriel multi-acteurs ? Cet article se structure à travers le prisme de la stratégie territoriale et ses composantes. Le terrain repose sur l’étude d’un programme régional dont l’objectif est d’accueillir et de produire, à terme, une innovation thérapeutique.
Exploring effects of Egoscue versus lumbar stabilisation exercises for lower crossed syndrome on postural stability and hyperlordotic posture correction
Authors: Sequeira S.E. , Gurudut P. , Kage V. 
Published: April 2023

Abstract
The aim of the study was to evaluate the comparative effectiveness of Egoscue exercises and lumbar stabilisation exercises in individuals with the lower crossed syndrome in terms of hyperlordotic posture correction, postural stability, and patient satisfaction towards treatment. The study was a randomised controlled trial. Through randomisation, 30 participants were allocated into 2 study groups, the Egoscue Exercise (EE) group (n=15) and the lumbar stabilisation exercise (LSE) group (n=15). The outcome measures were the degree of lumbar lordosis, functional disability, and postural stability parameters (risk of fall, stability index, weight distribution, anterior-posterior sway, and lateral sway) and patient satisfaction with treatment assessed at baseline and post-10th session of the intervention. Within group analysis showed significant improvement in the outcome measures, such as Index of Lumbar Lordosis, functional disability, postural stability, and patient satisfaction towards treatment with the groups (P<0.05). Between groups analysis showed that EE group and LSE groups were equally effective in improving lumbar hyperlordosis (P=0.458), functional disability (P=0.545), postural stability (risk of fall P=0.781; stability index P=0.964; weight distribution index P=0.718; anterior-posterior sway P=0.402; lateral sway P=0.212) and patient satisfaction towards treatment (P=0.999). Egoscue exercises and lumbar stabilisation exercises are equally effective in correcting lumbar hyper lordotic posture, postural stability, pain, and functional disability in low back pain individuals with the lower crossed syndrome.
Clinical Trials Registry – India (CTRI): CTRI/2021/09/036733
Economic Evaluation of Artificial Intelligence Systems Versus Manual Screening for Diabetic Retinopathy in the United States
Authors: Chawla Harshvardhan , Uhr Joshua H. , Williams Jonathan S. , Reinoso Maria A. , Weiss Jayne S. 
Published: April 2023

Background:
The objective of this economic modeling study was to compare the cost effectiveness of fully automated retinal image screening (FARIS) to the current practice of universal ophthalmologist referral for diabetic retinopathy in the United States (US) health care system.

Methods:
A Markov decision-analytic model was used to compare the automated versus manual screening and management pathway for diabetic patients with unknown retinopathy status. Costs (in 2021 US dollars), quality-adjusted life year (QALY) gains, and incremental cost-effectiveness ratios were calculated. Sensitivity analysis was performed against a $50,000/QALY willingness-to-pay threshold.

Results:
FARIS was the dominant screening strategy, demonstrating cost savings of 18.8% at 5 years with equivalent net QALY gains to manual screening. Cost-effectiveness status was dependent on FARIS detection specificity, with a threshold value of 54.8%.

Conclusion:
Artificial intelligence-based screening represents an economically advantageous screening modality for diabetic retinopathy in the US, offering equivalent long-term utility with significant potential cost savings.

[
Ophthalmic Surg Lasers Imaging Retina
2023;54:272–280.]
Knowledge and practice of malaria prevention among residents of Ratuwamai Municipality, Nepal
Authors: Karki Rajesh , Bartoula Niruta , Kaphle Maheshor , Shah Sanjaya Kumar 
Published: April 2023

Objective:
To assess the level of knowledge and practice on malaria prevention among the residents of Ratuwamai Municipality in Nepal.

Methods:
A community-based cross-sectional study was carried out on Ratuwamai Municipality of Ward No. 8 in Morang District, Nepal. A total of 352 respondents with an age range from 15 to 70 years were interviewed from October 9 to October 31, 2022. Statistically significant differences between two or more categorical groups were measured using independent sample t-test, one-way ANOVA test, and Kruskal-Wallis H test.

Result:
Out of the total sample, 57.7% of the respondents were 24 to 50 years old with a mean age of (36.9±14.3) years. In the knowledge test, 82% of the responses were accurate. Though 98.6% of people had heard of malaria, only 48.3% said it was a communicable disease. In practice, 84.9% always cleaned the surrounding area and trimmed the bushes around the house; 75.9% used insecticide-treated bed nets or normal bed nets for sleeping; only 7.4% used mosquito repellent creams on exposed body parts while staying outdoors at night, working in fields, and sleeping.

Conclusions:
The majority had knowledge about malaria, but more than half had poor practice. We advise concerned authorities to promote the behavior change communication strategy to encourage individuals to adopt healthy, beneficial, and good behavioral practices.
An Updated Review on Current Treatment of Alopecia Areata and Newer Therapeutic Options
Authors: Malhotra Karan , Madke Bhushan 
Published: April 2023

ABSTRACT
Alopecia areata (AA) is a dermatological disease that causes nonscarring hair loss. It can occur at any age and has an unpredictable and variable evolution in individuals. The aim of this review is to provide an update on the novel therapies currently being used, as well as upcoming therapeutic options in the treatment of AA.
Mesotherapy with Bicalutamide
Authors: Gomez-Zubiaur Alba , Andres-Lencina Juan Jose , Cabezas Víctor , Corredera Cristina , di Brisco Fabio , Ferrer Blanca , Rodriguez-Villa Ana , Subiabre-Ferrer Daniela , Valenzuela Cristian , Diez David Vega , Ricart Jose Maria 
Published: April 2023

ABSTRACT
Bicalutamide is a selective androgen receptor antagonist. To date, it has been used orally with good efficacy results, but not in mesotherapy. In our center, we assessed whether patients undergoing bicalutamide mesotherapy showed positive responses and tolerated the local administration of bicalutamide. Six premenopausal women, with a mean age of 35.7 years and clinical diagnosis of Olsen Grade II or III female androgenetic alopecia accompanied by significant seborrhea were treated with 1 ml bicalutamide 0.5% mesotherapy. Three monthly sessions were performed. A subtle improvement in hair density was described after the third session. The overall satisfaction of the patients with the treatment was 6.3, on a scale of 1–10. Premenopausal women require several therapeutic approaches to combat severe androgenetic alopecia. Our data showed that bicalutamide mesotherapy was well tolerated and welcomed by the patients; we, therefore, provide a new tool for the management of this pathology.
A Rare Case Report of Extradural Cervical Spine Meningioma
Authors: Ahmed Parwej , Gupta Rahul K. , Khan Azad , Siddiqui Areeb A. 
Published: April 2023

Introduction:
Extradural spinal meningiomas of the cervical spine are relatively uncommon. The vast majority of meningiomas develop in intracranial, intradural locations, and the majority of meningiomas affect the thoracic spine.

History:
A 39-year-old man presented with complaints of weakness in all four limbs for the last 8 months with bowel bladder involvement.

Clinical Features:
The patient had spastic quadriparesis with bowel and bladder involvement with planter extensors and the presence of patellar and ankle clonus.

Investigation:
Histopathopathology and immunohistochemical markers were sent and diagnosis of meningioma was made.
Designing a tool for measuring determinants of eye self-care and evaluating its psychometric properties
Authors: Chatripour Rahmat , Feizi Awat , Zamani-Alavijeh Fereshteh , Beni Afsaneh Naderi , Mazaheri Maryam Amidi 
Published: April 2023

Background:
Eye care is crucial for maintaining healthy vision. This study aimed to design a determinants assessment instrument related to eye self-care in the student community and evaluate its psychometric properties.

Materials and Methods:
The present mixed-method cross-sectional study was conducted in two sections using Creswell and Plano Clark methods for instrument development. The study was conducted in Isfahan, Iran, in 2021. The first section (textual analysis and qualitative research) explained and developed the instrument's fundamental items. This section included in-depth, semi-structured interviews with 21 students and eight experts. In the second, the psychometric properties of the designed instrument have been evaluated. Twenty students assessed the instrument's qualitative and quantitative face validity. The instrument's content was measured by computing the content validity ratio and content validity index. In addition, exploratory factor analysis (performed on 251 students) was used to establish construct validity. Internal and test–retest reliability was determined using Cronbach's alpha and intraclass correlation coefficients (ICC), respectively.

Results:
During face and content validity assessment, a 39-item questionnaire was finalized. Exploratory factor analysis led to the extraction of seven factors, including “perceived self-efficacy and self-regulation,” “outcome expectation,” “perceived barriers,” “motivation,” “perceived susceptibility,” “normative beliefs,” and “perceived severity.” The seven extracted factors explained 48.6% of the total variance. Cronbach's alpha was obtained to be 0.780, indicating good internal consistency, and the ICC for the total score of the questionnaire was 0.892 (95% confidence interval: 0.822–0.944), indicating excellent test–retest reliability.

Conclusion:
Our developed questionnaire was a valid and reliable instrument for assessing eye care determinants among students, a vulnerable population afflicted with eye defects and disorders.