bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rainfall extreme events and socio-physical effects on a temperate hydrographic basin in Argentina
Authors: Mastrandrea Aldana , Bohn Vanesa Y. 
Published: February 2023

Abstract

The increase of Rainfall Extreme Events (REE) intensity and frequency is a typical situation in the current context of Global Climate Change. The aim is to identify REE occurrence using modeled daily rainfall (DR) data analysis and quantify its effects on the Surface Soil Wetness (SSW), as a physical feature of the Napostá Grande (NG) hydrographic basin, differentiating by homogeneous units (HU). And to analyze the occurrence of REE and its social effects in the study area, through a press revision. The methodology includes the DR and SSW data analysis through data series provided by the National Aeronautics and Space Administration (NASA) for the period 1981–2022. Results indicated that the characteristics and the effects of the REE were differentiated along the hydrographic basin. Moreover, we could demonstrate a positive relationship between REE, SSW, and their social effects. Although the highest proportion of extreme events was manifested in the sedimentary fills HU and paleodrains HU, those extreme events that had a greater relevance, due to their social effects, were those that occurred in the urban area. Regarding the effects, an increase and a decrease in the SSW were found during the REE occurrences and normal rainfall, respectively. REE between 50–100 mm were more usual in the paleodrains HU and sedimentary fills HU than the others. This research constitutes a case study, which demonstrates how useful the inclusion of climatic REE and SSW data and press revision can be used for an optimal management of water resources/forecasting flood damage.
Association between Parameters of Cortisol Metabolism, Biomarkers of Minerals (Zinc, Selenium and Magnesium) and Insulin Resistance and Oxidative Stress in Women with Obesity
Authors: Morais Jennifer , Cruz Kyria , Oliveira Ana Raquel , Melo Stéfany , Santos Loanne , Cardoso Bruna , Dias Thaline Milany Silva , Severo Juliana Soares , Henriques Gilberto Simeone , Silva Moisés Tolentino Bento , Oliveira Francisco Erasmo , Marreiro Dilina 
Published: February 2023

AbstractCross-sectional study with women divided into a group of women with obesity (n=80) and a control group (n=94). Statistical analysis was conducted using the SPSS program. There were high values of GPX and MDA, and reduced values of SOD in women with obesity compared to the control group. Obese women showed increased concentrations of cortisol in serum and urine, as well as hypozincemia, hyposelenemia and hypomagnesemia and increased urinary excretion of these minerals. There was a negative correlation between the cortisol/cortisone ratio and erythrocyte zinc and selenium concentrations, a significant positive correlation between GPx and SOD activity and erythrocyte and plasma concentrations of zinc and selenium. The results of the study suggest the influence of adiposity on the increase in cortisol concentrations, the role of this hormone in the compartmentalization of the minerals zinc, selenium and magnesium. However, the association study does not allow identifying the impact of such action on the antioxidant defense system and insulin sensitivity.
Relationship between soil seed bank and standing vegetation: An effective approach to conclude plant invasion pattern in Indian dry tropical peri-urban region
Authors: Aggarwal Shilpi , Narayan Rup 
Published: February 2023

Abstract
The natural and semi-natural ecosystems of dry tropical regions are characterized by a high biodiversity with the new introduction of alien invasive species, especially at disturbed sites. The tropical regions due to favorable environmental conditions are considered rich reservoirs of much of the biodiversity of the earth. The Indian dry tropical urban region has also been reported to be highly diverse but fragile with abundant alien flora, of which American, Asian, and European and Asian species form the major contributions. By the allelopathic activity, these weeds alter the soil environment, cause low productive systems with weak soil microflora and accelerate their fast spread by fast colonization, fast reproduction, or highly competitive ability. These weedy species have a great potential to make persistent soil seed banks. The soil seed bank is a reservoir of viable but ungerminated seeds and acts as a genetic reservoir that could play an important role in determining the future vegetation of the community. The present study carried out four different land use patterns and focused on the seed bank dynamics of these sites. In this study, the abundance of alien invasive species in the floristic composition and density of the subterranean vegetation reflects the impact of disturbance and other anthropogenic factors.
Landscape Context for Forest Transition Success in Central Panama
Authors: Bardino Giulia , Fonzo Gianrico Di , Walker Kendra , Vitale Marcello , Hall Jefferson S. 
Published: February 2023

Abstract
Context
Secondary forests are frequently re-cleared before they can recover to pre-disturbance conditions. The identification of factors associated with passive regeneration persistence success would help planning cost-efficient forest restoration.
Objectives
In this paper we investigated the role that the landscape context of naturally regenerated forest patches plays for their chances to mature and persist in time in central Panama. Maturation and persistence of secondary forests are concepts often undervalued representing, however, essential requisites for an effective and long-term restoration of the ecosystem processes.
Methods
A unique data set of land-cover maps of central Panama was used to identify the forest patches that naturally recovered and persisted between 1990 and 2020. We developed a Random Forest Classification (RFC) calibration method to identify areas with higher likelihood of forest persistence success.
Results
The RFC model discriminated between areas that naturally recovered and persisted in time and areas that did not persisted with an error rate of 2%. By tuning, we obtained a precision of 0.94 (94%) in the validation test. Based on the model, we developed a prediction map of central Panama areas with higher probability (≥ 90%) of secondary forests persistence success within the next 20 years.
Conclusions
Tracking simple landscape and socio-economic metrics allowed for a deeper understanding of the underlying mechanisms of secondary forest persistence in central Panama. Through the development of RFC calibration method, this study maximized the reliability of the patches identified as suitable to persistence success, representing a basis for management decisions and future investigations for a successful, long-term forest-landscape restoration.
Improved Quality Control of [177Lu]Lu-PSMA I&amp;T
Authors: Kraihammer Martin , Garnuszek Piotr , Bauman Andreas , Maurin Michael , Lafont Manuel Alejandre , Haubner Roland , von Guggenberg Elisabeth , Gabriel Michael , Decristoforo Clemens 
Published: February 2023

Abstract
Background: Targeted radionuclide therapy with [177Lu]Lu-PSMA I&T (Zadavotide guraxetan) has proven high efficacy and safety in treating patients with advanced prostate cancer worldwide. Several methods to determine the radiochemical purity have been reported but also limitations in the HPLC analysis due to retention of the sample and tailing effects when using standard gradients containing trifluoroacetic acid (TFA). We here report on the validation of a method for quality control of [177Lu]Lu-PSMA I&T including determination of radiochemical purity, identity testing and limit test for PSMA I&T by HPLC using a Phosphate buffer /Acetonitrile gradient system, complemented with a TLC system with 0.1N Citrate buffer pH5 as mobile phase including validation of the methods, batch and stability data as well as identification of the main radiochemical impurity by mass spectrometry.
Results: The described HPLC method met the defined acceptance criteria in terms of accuracy, specificity, robustness, linearity, range and LOQ. HPLC analysis revealed symmetrical peaks and quantitative recovery from the column. Batch data showed a radiochemical purity >95% as determined by HPLC, stability data a pronounced degradation due to radiolysis, which could be limited by addition of ascorbic acid, dilution and storage at low temperatures. The main radiochemical impurity was found to be the de-iodinated form of [177Lu]Lu-PSMA I&T. TLC analysis allowed to determine the amount of free Lu-177 even in the presence of DTPA in the final formulation.
Conclusion: Overall the described combination of HPLC and TLC provides a reliable tool for quality control of [177Lu]Lu-PSMA I&T.
Creep behavior of glass fiber reinforced glulam beams under uncontrolled variable climatic conditions
Authors: Song Yo-Jin , Lee In-Hwan , Hong Soon-Il 
Published: February 2023

Abstract
The glass fiber reinforcement of the tensile part of a glulam beam is known to increase its short-term bending performance. Under variable climatic conditions, improvements in short-term bending performance are anticipated to improve long-term creep performance. In this study, the creep behavior of glulam beams reinforced with glass fibers and unreinforced glulam beams was investigated for 18240 hours under uncontrolled variable climatic conditions. Depending on the presence or absence of reinforcement and the type of reinforcement, several aspects of the creep behavior of glulam beams could be observed. Through the glass fiber reinforcement of the glulam beam, it was possible to lower the amount of the creep variation as well as the overall creep strain after 18240 hours. Specifically, the glass fiber reinforced plastic reinforcement sheet caused the glulam beam to exhibit a consistent creep behavior regardless of the stress level. This improved the predictability of long-term creep deformation under variable and uncontrolled climatic conditions.
GUP modified Wigner function using classical-quantum unified framework
Authors: Sen Abhijit , Parida Bikram Keshari 
Published: February 2023

Abstract
The generalized uncertainty principle (GUP) is a natural consequence
of many proposed quantum gravity theories which further indicates
the modification of the quantum mechanics and classical mechanics.
A unified classical-quantum framework also leads to the interpretation of a Winger phase-space distribution of a state as a KvN wave function. In this article, we utilize the classical-quantum unified framework to calculate the expression for the GUP modified Wigner function of a classical harmonic oscillator in the configuration space instead of the conventional approach of utilising the momentum space. Further, we plot the modified Wigner functions and show that they are similar to what has been obtained before in the past literature.
Production of recombinant proteins including the B-cell epitopes of autolysin A of Staphylococcus aureus isolated from clinical sheep mastitis and their potential for vaccine development
Authors: Azara Elisa , Foddai Antonio Carlo , Longheu Carla Maria , Addis Maria Filippa , Tola Sebastiana 
Published: February 2023

Abstract
Staphylococcus aureus is the most common clinical mastitis-associated pathogen in sheep which contributes to reduced welfare of affected animals and, therefore, compromises the quality and quantity of milk production. To prevent mastitis and its spread, it is essential to guarantee adequate breeding conditions and animal health, through the adoption of good farm management practices and the application of suitable biosecurity measures. Vaccination can play a strategic role in prevention, control, and eradication of diseases. The identification of secreted and cellular antigens of the predominant sheep-CC130/ST700/t1773 lineage would assist in the design of effective vaccine against mammary infections caused by S. aureus. In the current study, we carried out a 3D structural prediction analysis with the identification of the best B cell epitopes of the whole and secreted portion of S. aureus AtlA. Fragments of atlA, containing the main predicted epitopes, were amplified, cloned, and expressed in Escherichia coli for recombinant protein production. Two selected clones produced recombinant proteins (rAtl4 and rAtl8) showing strong reactivity with a hyperimmune serum against the native AtlA and with blood sera collected from sheep with clinical S. aureus mastitis. These may represent potential candidate protein-based vaccines able to elicit a protective immune response to be evaluated by vaccination and subsequent challenge of the vaccinated sheep.
Discard butterfly local extinctions through untargeted citizen science: the interplay between species traits and user effort
Authors: Tongeren Elia van , Sistri Ginevra , Bonifacino Marco , Menchetti Mattia , Pasquali Lorenzo , Salvati Vania , Balletto Emilio , Bonelli Simona , Cini Alessandro , Portera Mariagrazia , Dapporto Leonardo 
Published: February 2023

Abstract
The detection of extinctions at local and regional scales in many biodiversity hotspots is often hindered by the lack of long-term monitoring data, and thus relies on time series of occurrence data. Citizen science has repeatedly shown its value in documenting species occurrences, mostly in very recent years. This study investigates the effectiveness of untargeted citizen science records in discarding the possibility of local extinctions in butterfly populations across all Italian National Parks. We addressed three research questions: i) the ability of citizen science data to supplement existing knowledge to complete occurrences time series, ii) the impact of functional traits determining species appearance on data collection, and iii) the interplay between participant engagement and species appearance in the amount of diversity recorded on the iNaturalist platform. Our analysis of 47,356 records (39,929 from literature and 7,427 from iNaturalist) shows that the addition of iNaturalist data fills many recent gaps in occurrence time series, thus reducing the likelihood of potential local extinctions. User effort strongly interacts with species size, distribution, and length of flight periods in determining the frequency of records for individual species. Notably, records from more engaged users encompass a higher fraction of local biodiversity and are more likely to discard local extinctions, and these users are less affected by species size. We also provide updated butterfly checklists for all Italian National Parks and a new R package to calculate potential extinction over time. These results offer guidance for protected areas, conservationists, policymakers, and citizen scientists to optimise monitoring of local populations.
Time to Dismiss Boost? Outcomes of Children With Localized and Metastatic Germinoma.
Authors: Foo Jen Chun , Bajin Inci Yaman , Marushchak Oksana , McKeown Tara , Bouffet Eric , Tsang Derek S. , Laperriere Norman , Dirks Peter , Drake James , Ertl-Wagner Birgit , Bartels Ute 
Published: February 2023

Abstract
Purpose: To determine long-term outcomes of a cohort of children with germinoma treated with chemotherapy and radiation therapy without primary tumor boost even in the absence of complete response to chemotherapy.
Methods: This retrospective study analyzed the outcome of patients with germinoma consecutively diagnosed and treated at a tertiary care center from January 2000 to December 2021. MRIs were reviewed by two radiologists, blinded to patient data. Tumor location at diagnosis, tumor response to chemotherapy and at completion of radiation therapy and site of relapse were assessed. Tumor response was assessed radiologically by determining the tumor size and response on diffusion-weighted imaging, in addition to biochemical, cytological parameters and neurological status.
Results: Of 46 pediatric germinoma patients, 29 children (14 male; median age 12.8 years) received no primary tumor boost. Median follow-up was 63 months (range 9-187 months). Twenty-five children had localized disease and tumor location was suprasellar (n= 11), pineal (n= 10), bifocal (n= 3) and basal ganglia (n= 1) while 4 children had metastatic disease at presentation. All patients completed multi-agent chemotherapy followed by either ventricular irradiation (VI) (23.4 Gy) (n = 23), whole brain (WBI) (23.4 Gy) (n = 5) or craniospinal radiation (CSI) (23.4 Gy) (n= 1). Two children, who had localized disease at presentation and received VI after chemotherapy, relapsed 9 months and 32 months after completion of treatment respectively. No patient had a local relapse. Location of relapse was distant, outside (n= 1) and inside (n= 1) the irradiation field. Five-year PFS was 91% and overall survival (OS) was 100%.
Conclusions: In this case series, excellent 5-year PFS and OS rates were achieved with chemotherapy followed by radiation therapy of 23.4 Gy delivered without primary tumor boost. No local relapse was observed despite omitting primary tumor boost in patients with localized and metastatic germinoma.
WITHDRAWN: Effect of lead core size and arrangement on the shear and axial behavior of the lead rubber bearings
Authors: Kazeminezhad Ehsan , raoufi reza 
Published: February 2023

Abstract

Earthquake forces have always been considered as a threat to the structures. One of the most effective ways to have structures with minimal damage and improve their resilience is prevent transmission of earthquake forces to the superstructures. For this purpose, the base isolation method can be implemented. Common types of base isolators are elastomeric rubber bearing and lead rubber bearing. Elastomeric rubber bearing is consisting rubber layers and intermediate steel plates that are produced by vulcanization process and lead rubber bearing (LRB) is similar to the elastomeric rubber bearing but a lead core is located in the center. In this study, shear behavior and vertical stiffness of LRBs are evaluated with the finite element approach. Validation analysis was performed which indicated the accuracy of modeling and then two full scale circle LRBs were selected from Bridgestone corporation with 1000 and 600mm diameters. The main purpose of this paper is evaluating the effect of lead core size, number and location on the shear behavior and vertical stiffness of lead rubber bearings.
Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence.
Authors: Farid Nesma Medhat , Chun Sungsoo , Hassanain Omneya , Salama Mohamed , Esam Elham , Adel Fatima , Rashad Ismail , Ghoneimy Ahmed Mohamed El 
Published: February 2023

Abstract
Purpose
Our study pursued cross-cultural adaptation, and validation of the pediatric Toronto Extremity Salvage Score (pTESS) and Toronto Extremity Salvage Score (TESS) to assess the functional outcome for Egyptian children and adult survivors of childhood bone cancer. Mental domains were added to allow the evaluation of health-related quality of life (HRQOL)
Methods
The internal consistency and test-retest reliability of the studied forms were assessed. For convergent validity, correlations between scores of the generic Pediatric Quality of Life Inventory (PEDSQL 4.0) and pTESS /TESS scores were reported. Exploratory Factor Analysis (EFA) was feasible for pTESS-leg; due to the insufficient samples, only the average inter-item correlation coefficients were reported for the remaining versions.
Results
Out of 233 participants, 134 responded to pTESS leg, 53 to TESS-leg, 36 to pTESS-arm, and only 10 to TESS-arm. All versions showed excellent internal consistency (Cronbach’s alpha > 0.9), good test-retest reliability (Intra-class coefficients > 0.8), moderate to strong correlations with PEDSQL, and acceptable average inter-item correlation coefficients (≥ 0.3). In the EFA, all mental items were loaded on one separate factor with factor loadings exceeding 0.4. Chemotherapy, primary surgery within one year, or tibial tumors showed significantly inferior pTESS/TESS scores in lower extremities.
Conclusion
The Egyptian pTESS and TESS are valid and reliable self-reporting tools for assessing the functional outcome following surgeries of extremity bone sarcomas. The mental domains enabled the assessment of the overall health status in our population. Future studies should include larger sample size and evaluate the ability of pTESS/TESS to track progress over time.
Road networks: A new filtering approach to extract backbones using community structure
Authors: GHALMANE Zakariya , Brahmia Mohamed-El-Amine , Zghal Mourad 
Published: February 2023

Abstract
Road networks represented as a networked system of edges and nodes have raised considerable interest in the literature of networks, leading to numerous studies throughout the years. In these networks, the junctions where roads intersect are represented by nodes while the road segments connecting them represent the edges. Road networks in major cities and metropolises all over the world are very large-scale dense networks. Thus, the need to identify the most important roads that influence both vehicle and pedestrian flows, urban crime, collective dynamic behavior, land-use separation and retail vitality. In this context, in this paper, we propose a new method to extract the skeleton or the backbone of cities. The so-called "Link Motif-Betweenness skeleton (LMB)" aims to select the links belonging to the larger number of motifs in the network and also having high betweenness. The LMB selects links separately from two sub-networks: from the local sub-network which is formed only from the intra-community links to select edges with a local influence in the various communities, and also from the global sub-network which is formed from the inter-community links of the network to select edges with a global influence all over the network. The proposed method is tested on road networks in the five largest cities of France: Paris, Marseille, Lyon, Toulouse and Nice. Experimental results show the efficiency of the LMB in terms of preserving relevant roads as compared to some alternative methods.