bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deux féminités marginales en miroir : la prostituée dans le regard des femmes reporters de l’entre-deux-guerres
Authors: Simard-Houde Mélodie 
Published: April 2023

À la croisée des années 1920 et 1930, en France, plusieurs femmes reporters – soit Maryse Choisy, Magdeleine Paz, Marise Querlin, Luc Valti et Adrienne Verdière Le Peletier – s’emparent du sujet de la prostitution. Cet article interroge ces enquêtes afin d’examiner le regard féminin porté sur cette question et sur la figure de la prostituée. Il met en lumière les ambivalences des reportages, qui hésitent entre la reconduction de stéréotypes prégnants de l’imaginaire de la prostitution, hérités des enquêtes sociales et de la littérature du xixe siècle, et l’invention d’une vision neuve du problème. La figure de la prostituée est au coeur de cette tension : à la fois victime et criminelle, femme pure et impure, ordinaire et marginalisée, elle marque les reportages de sa voix et des aventures de son corps, tout en fournissant à la femme reporter un symbole social et réflexif. Elle lui permet en effet de dénoncer certains aspects qui touchent plus généralement la condition des femmes françaises de l’entre-deux-guerres, les inégalités de genre et de classe, mais aussi de dire quelque chose de la condition un peu marginale qu’ont en commun la fille publique et la femme reporter, à l’identité mobile et hors-norme.
L’identité au coeur de l’intégration de l’aide médicale à mourir au sein de la pratique médicale : résultats d’une recherche qualitative sur l’expérience des médecins qui l’administrent
Authors: Lacharité France 
Published: April 2023

Contexte : Depuis 2015, les médecins sont les seuls professionnels de la santé qui ont le pouvoir légal d’administrer l’aide médicale à mourir (AMM) au Québec. Un nouveau contexte législatif amène des changements majeurs au sein de leur pratique de soins de fin de vie. Objectif : Explorer les facteurs de sens qui émergent de l’expérience vécue par les médecins administrant l’AMM afin de mettre en lumière ce qui les conduit à intégrer cette pratique dans leur continuum professionnel. Méthodologie : Des entretiens semi-dirigés ont été menés auprès de dix médecins ayant pratiqué minimalement une AMM sur l’ensemble du territoire du CIUSSS de l’Estrie. Analyse : Réalisé à partir de la théorisation ancrée de Pierre Paillé (1994), l’analyse a montré que l’AMM est une démarche humaine demandant du temps et des aptitudes sociales, où le savoir-être est primordial. Les résultats suggèrent que l’AMM est située aux frontières de l’identité personnelle et professionnelle du médecin. En somme, ce qui incite un médecin à participer au processus d’AMM est son identité narrative comprenant les valeurs et le sens qu’il donne à son parcours expérientiel. Conclusion : L’AMM est un soin ayant une portée existentielle et son processus est vécu différemment par chaque médecin ; il importe donc de respecter le sens et les valeurs de chaque médecin, qu’il intègre ou non l’AMM dans sa pratique médicale.
Evolutionary analysis of the OSCA gene family in sunflower (Helianthus annuus L) and expression analysis under NaCl stress
Authors: Shan Feibiao , Wu Yue , Du Ruixia , Yang Qinfang , Liu Chunhui , Wang Yongxing , Zhang Chun , Chen Yang 
Published: April 2023

Hyperosmolality-gated calcium-permeable channels (OSCA) are Ca2 + nonselective cation channels that contain the calcium-dependent DUF221 domain, which plays an important role in plant response to stress and growth. However, the OSCA gene has not been fully identified and analyzed in sunflowers. In this study, we comprehensively analyzed the number, structure, collinearity, and phylogeny of the OSCA gene family in the sunflower, six Compositae species (Arctium lappa, Chrysanthemum morifolium, Cichorium endivia, Cichorium intybus, Lactuca sativa var. Angustata, and Carthamus tinctorius), and six other plants (soybean, Arabidopsis thaliana, rice, grape, and maize). The expression of the sunflower OSCA gene in nine different tissues, six different hormones, and NaCl stress conditions were analyzed based on transcriptome data and qRT–PCR. A total of 15 OSCA proteins, distributed on 10 chromosomes, were identified in the sunflower, and all of them were located in the endoplasmic reticulum. Using the phylogenetic tree, collinearity, gene structure, and motif analysis of the six Compositae species and six other plants, we found that the sunflower OSCA protein had only three subfamilies and lacked the Group 4 subfamily, which is conserved in the evolution of Compositae and subject to purification selection. The OSCA gene structure and motif analysis of the sunflower and six Compositae showed that there was a positive correlation between the number of motifs of most genes and the length of the gene, different subfamilies had different motifs, and the Group 4 subfamily had the smallest number of genes and the simplest gene structure. RNA-seq and qRT–PCR analysis showed that the expression levels of most OSCA genes in the sunflower changed to varying degrees under salt stress, and HaOSCA2.6 and HaOSCA3.1 were the most important in the sunflower’s response to salt stress. The coexpression network of the sunflower genes under salt stress was constructed based on weighted gene co-expression network analysis (WGCNA). In conclusion, our findings suggest that the OSCA gene family is conserved during the sunflower’s evolution and plays an important role in salt tolerance. These results will deepen our understanding of the evolutionary relationship of the sunflower OSCA gene family and provide a basis for their functional studies under salt stress.
Selective Potassium Deposition Enables Dendrite‐Resistant Anodes for Ultrastable Potassium‐Metal Batteries
Authors: Feng Yanhong , Rao Apparao M. , Zhou Jiang , Lu Bingan 
Published: April 2023

AbstractInstability at the solid electrolyte interface (SEI) and uncontrollable growth of potassium dendrites have been pressing issues for potassium‐ion batteries. Herein, a self‐supporting electrode composed of bismuth and nitrogen‐doped reduced graphene oxide (Bi80/NrGO) is designed as an anode host for potassium‐metal batteries. Following the molten potassium diffusion into Bi80/NrGO, the resulting K@Bi80/NrGO exhibits unique hollow pores that provide K+‐diffusion channels and deposition space to buffer volume expansion, thus maintaining the electrode structure and SEI stability. The K@Bi80/NrGO also provides a controlled electric field that promotes uniform K+ flux, abundant potassiophilic N sites, and Bi alloying active sites, collectively enabling precise nucleation and selective deposition of potassium to achieve dendrite‐resistant anodes. With the K@Bi80/NrGO‐based optimized electrodes, the assembled K@Bi80/NrGO symmetrical cells can sustain stable cycling over 3000 h at a current density of 0.2 mA cm−2. Full cells with a Prussian blue cathode and K@Bi80/NrGO anode exhibit high stability (with no degradation for 1960 cycles at 1000 mA g−1) with 99% Coulombic efficiency. This work may lead to the design of anodes with the triple attributes of precise nucleation, smooth diffusion, and dendrite inhibition, ideal for developing stable potassium‐metal anodes and beyond.
Defect‐Rich MoSe2 2H/1T Hybrid Nanoparticles Prepared from Femtosecond Laser Ablation in Liquid and Their Enhanced Photothermal Conversion Efficiencies
Authors: Ye Fan , Ayub Ahsan , Karimi Reza , Wettig Shawn , Sanderson Joseph , Musselman Kevin P. 
Published: April 2023

AbstractMoSe2 2H/1T hybrid nanoparticles are prepared by femtosecond laser ablation of MoSe2 powder in isopropyl alcohol with different laser powers and ablation times, and their formation mechanisms and photothermal conversion efficiencies (PTCEs) are studied. Two types of spherical nanoparticles are observed. The first type is onion‐structured nanoparticles that are formed by nucleation on the surfaces of melted droplets followed by inward growth of {002} planes of MoSe2. The second type is polycrystalline nanoparticles, formed by coalescence of crystalline nanoclusters fragmented from the powder during the laser ablation. The nanoparticle size in all samples shows a bimodal distribution, corresponding to different fragmentation mechanisms. The 2H‐to‐1T phase transition in the nanoparticles is likely caused by electron doping from the laser‐induced plasma. The PTCEs of the nanoparticles increase with laser power and ablation time; the highest PTCE is around 38%. After examining the bandgaps and the Urbach energies of the nanoparticles, it is found that the high PTCEs are primarily attributed to defects and structural disorder in the laser‐synthesized nanoparticles, which allow absorption of photons with energies smaller than the bandgap energy and facilitate non‐radiative recombination of photoexcited carriers.
A Memristive Cell with Long Retention Time in 65 nm CMOS Technology
Authors: Assaf Hussein , Savaria Yvon , Ali Mohamed , Nabavi Morteza , Sawan Mohamad 
Published: April 2023

AbstractThe memristor, which Leon Chua discovered in 1971 and Hewlett Packard fabricated for the first time in 2008, is still facing many design and fabrication challenges. Luckily, memristor emulators using mature Complementary Metal Oxide Semiconductor (CMOS) processes are good substitutes for memristors in several applications. The common setback for these emulators is their inability to retain their internal states for long periods of time. This article presents a memristive cell that not only has the memristor's characteristics but also can retain its resistance for up to 10 years. To bring forward such a cell, a charge trap in a 1 mm2 chip is designed and fabricated using a standard 65 nm CMOS process. By characterizing the proposed trap prototype, its unexpected yet interesting behavior is revealed, such as charge tunneling that occurrs at voltages between 350 mV and 650 mV despite the process sensitivity. Next, based on the measurement results and using the VerilogAMS programming language, the charge trap to be combined with other circuits that constitute the proposed memristive cell is modeled. This model, which is partly based on previously reported models, matches the measured characteristics of the fabricated charge trap and can be easily integrated into circuit simulations.
PVDF Based Static Charge Induced Flexoelectric Microphone
Authors: Shehzad Mudassar , Pan Han , Wang Shuhao , Wang Yaojin 
Published: April 2023

AbstractPolyvinylidenedifluoride (PVDF)‐based microphones are either categorized as piezoelectric (PE) microphones or flexoelectric (FE)‐induced PE microphones. Based on the production of electrostatic charge and higher sensitivity, here, a static charge induced flexoelectric microphone (SCIFEM) is introduced. In this research, two SCIFEM transducers are fabricated, one by sandwiching P(VDF‐TrFE) laminate between pair of two aluminum electrodes wrapped in stretched paper sheets (called Device 1) and the other by sandwiching P(VDF‐TrFE) laminate between a pair of two Al electrodes wrapped in stretched rubber sheets (called Device 2). Devices 1 and 2 are compared with a simple PVDF‐based FE microphone (called Device 0). In this study, Devices 0, 1, and 2 are characterized for flexoelectric (FE) and charge induction (CI) properties. It is observed that despite its poor FE behavior, higher sensitivity of Device 1 is due to its electrostatic charge induced beta phase present at 1170 cm−1 of Fourier transform infrared spectra. The X‐Ray diffraction spectroscopy is also performed in accordance to the polar beta phase. It is reported that due to the enhancement in beta phase and the unique charge induction property represented at 1170 cm−1 of the FTIR spectra, the performance of SCIFEM microphone is much improved at a lower frequency range.
Novel nonsense mutation in UNC80 in a Turkish patient further validates the sociable skill and severe gastrointestinal problems as part of disease spectrum
Authors: Kelesoglu Fatih M. , Kaya Mahsum , Sayili Ebrar Tuba 
Published: April 2023

AbstractNALCN channelosome complex contributes to maintaining resting membrane potential. The complex has four domains including two intracellular domains (UNC79 and UNC80), one transmembrane domain (NALCN) and one extracellular domain (FAM155A). Mutations in UNC80 were previously linked to infantile hypotonia with psychomotor retardation and characteristics facies 2. A 6‐year‐old male with neurodevelopmental disorder was referred for clinical exome sequencing. Sanger sequencing was conducted for variant confirmation and segregation analysis. The index had severe to profound neurodevelopmental delay, progressive failure to thrive, severe constipation and reflux, and sociable skills. Trio exome sequencing identified a homozygous c.6495G > A change causing p.Trp2165Ter in UNC80 in the proband. The variant was novel and predicted to be deleterious. We reported a novel nonsense mutation in UNC80. Our case also established the association between, and sociable skills and severe gastrointestinal problems.
RETRACTED: Multilayered nanocomposite coatings for enhanced anticorrosive, flame retardant, and mechanical properties in automobile and aerospace industries
Authors: Xavier Joseph Raj 
Published: April 2023

AbstractThe anticorrosion, flame retardant, and mechanical properties of polyurethane (PU) coatings have been improved by the integration of nickel disulfide (NiS2), 2,5‐Bis(4‐aminophenyl)‐1,3,4‐oxadiazole (BAO), and graphene oxide (GO). The structural, morphological, dielectric, and hydrophobic behaviors of the films were characterized for the different formulations of coatings such as pure PU, PU‐NiS2, PU‐BAO/NiS2, PU‐GO/NiS2, and PU‐GO/BAO‐NiS2 (nanocomposite) by means of scanning electron microscope/X‐ray energy dispersive spectroscopy, transmission electron microscope, thermogravimetric analysis, X‐ray photoelectron spectroscopy, X‐ray diffraction, and contact angle measurement. As a result, with the addition of only 0.3% GO/BAO‐NiS2, the dielectric constant of PU was increased by 81‐fold at 1 Hz. Additionally, the nanocomposite had significantly lower peak heat release rate and overall heat released values than pure PU, a difference of 57% and 51%, respectively, demonstrating its greater flame retardancy. The electrochemical techniques and mechanical testing confirmed that GO/BAO‐NiS2 (0.3%) composite exhibit enhanced anticorrosive, hydrophobic, flame retardancy, and mechanical performance of the PU coating. The super hydrophobic behavior is confirmed by its water contact angle of 165°. Furthermore, the resistance of the nanocomposite was found to be much higher (16,985.6 kΩ.cm2) than that of the pure PU (145.4 kΩ.cm2) and the microhardness and tensile strength were increased sharply. Therefore, the nanocomposite could act as a potential coating material for industrial applications.
Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design
Authors: Schanberg Laura E. , Mulugeta Lily (Yeruk) , Akinlade Bolanle , Brunner Hermine I. , Chen Jianmeng , Colbert Robert A. , Delgaizo Vincent , Gastonguay Marc R. , Glaser Rachel , Imundo Lisa , Lovell Daniel J. , Leu Jocelyn H. , Mostafa Nael M. , Nelson Robert M. , Nigrovic Peter A. , Nikolov Nikolay P. , Rider Lisa G. , Rothwell Rebecca , Sahajwalla Chandrahas , Singh Renu , Sinha Vikram , Yancey Carolyn L. , Yao Lynne 
Published: April 2023

ObjectiveStakeholders met to address persistent challenges facing the development of therapeutics for polyarticular juvenile idiopathic arthritis (pJIA), which result in fewer approved therapies for children with pJIA than adults with rheumatoid arthritis (RA) and long lag times from adult RA approval to pediatric labeling. Ensuring that new medications are authorized in a timely manner to meet the needs of JIA patients worldwide is critically important to multiple stakeholders.MethodsThe Food and Drug Administration in collaboration with the University of Maryland Center for Regulatory Science and Innovation held a public workshop entitled “Accelerating Drug Development for pJIA” on October 2, 2019, to address challenges surrounding access to new medications for children and adolescents with pJIA. Regulatory, academic, and industry stakeholders, as well as patient representatives, participated in the workshop, which consisted of 4 sessions, including panel discussions.ResultsThe workshop facilitated broad public discussion of challenges facing the development of pJIA therapeutics, highlighting areas of need and outlining opportunities to expedite development, while underscoring the necessity of close collaboration between all stakeholders, including patients and families.ConclusionThis report summarizes key aspects of the workshop, including the appropriate application of innovative approaches to the development of pJIA therapeutics, including extrapolation, to address current challenges and provide timely access to newer safe and effective treatments. Long‐term safety assessment is of pressing concern to stakeholders and cannot be fully extrapolated from adult studies but requires consistent postmarketing long‐term follow‐up.
Caspase 1 Enhances Transport and Golgi Organization Protein 1 Expression to Promote Procollagen Export From the Endoplasmic Reticulum in Systemic Sclerosis Contributing to Fibrosis
Authors: Connolly Lianne M. , McFalls Caya M. , McMahon Isabelle G. , Bhat Akash M. , Artlett Carol M. 
Published: April 2023

ObjectiveTransport and Golgi Organization protein 1 (TANGO1) is a protein that regulates the export of procollagen from the endoplasmic reticulum and has a role in the organization of exit sites for general protein export. What regulates the expression of TANGO1 and the role of TANGO1 in fibrosis is poorly understood and has never been studied in the setting of systemic sclerosis (SSc). We undertook this study to determine the role of TANGO1 in SSc fibrosis.MethodsSSc (n = 15) and healthy (n = 12) primary fibroblast lung cell lines were investigated for the expression of TANGO1. Histologic analyses for TANGO1 were performed on lung biopsy samples (n = 12 SSc patient samples and n = 8 healthy control samples).ResultsSSc fibroblasts showed increased expression of TANGO1 protein in cultured fibroblasts. TANGO1 colocalizes with α‐smooth muscle actin (α‐SMA)–positive cells in SSc lung tissue and is highly up‐regulated in the neointima of SSc vessels. TANGO1 expression was dependent on the inflammasome activation of caspase 1. It was also dependent on signaling from the interleukin‐1 (IL‐1) and transforming growth factor β (TGFβ) receptors. The decrease in TANGO1 down‐regulated export of larger cargos including collagen and laminin. Reduced TANGO1 protein had no effect on smaller molecular weight cargoes; however, the secretion of elastin was significantly reduced.ConclusionTANGO1 is markedly increased in SSc fibroblasts and was found to be elevated in lung tissue in association with α‐SMA–positive cells. TANGO1 expression is driven by inflammasome‐dependent caspase 1 activation and is mediated by IL‐1 and TGFβ downstream signaling. These observations suggest that during fibrosis, caspase 1 promotes the up‐regulation of TANGO1 and the organization of endoplasmic reticulum exits sites, ultimately contributing to procollagen export and fibrosis.image
A Simple and Fast Access to Phosphine‐Substituted Copper(I)‐Carbene Complexes via C=Se Bond Cleavage Reaction
Authors: Veerapathiran Sabari , Prabusankar Ganesan 
Published: April 2023

AbstractPhosphine coordinated copper(I)‐N‐heterocyclic carbene complexes have emerged as an efficient material in catalysis and light‐emitting applications. In this study, a gentle and sustainable approach to the copper(I)‐carbene phosphine complexes is reported through an efficient C=Se activation protocol. The complexes [(Py^NHC)Cu(PPh3)2]X, X=BF4 (1), ClO4 (2), PF6 (3) and OTf (4); Py^NHC=3‐isopropyl‐1‐(pyridin‐2‐yl)‐imidazol‐2‐ylidene, and [(Py^NHC)Cu(PPh3)(X)], X=Br (5) and I (6) have been synthesized by treating 1‐isopropyl‐3‐(pyridin‐2‐yl)‐imidazole‐2‐selone with corresponding copper(I) precursors and triphenylphosphine. In this synthetic strategy, N‐heterocyclic carbene gets transferred from N‐heterocyclic selone through a C=Se bond cleavage reaction to form copper(I) complexes within five minutes at room temperature. In addition, the mechanism responsible for the C=Se bond cleavage reaction has been fully investigated. These reactions are not sensitive to moisture and oxygen.
Preferences for honesty can support cooperation
Authors: Szekely Aron , Bruner David , Steinmo Sven , Todor Arpad , Volintiru Clara , Andrighetto Giulia 
Published: April 2023

AbstractMany collective action problems are inherently linked to honesty. By deciding to behave honestly, people contribute to solving the collective action problem. We use a laboratory experiment from two sites (n = 331 andn = 319) to test whether honest preferences can drive cooperation and whether these preferences can be differentially activated by framing. Subjects participate in an asymmetric information variant of the public goods game in one of two treatments that vary only in their wording: The Contribution Frame uses a standard public good game framing, while in the Honesty Frame, words aimed to trigger honesty are used. We measure subjects' honesty in three ways using the (i) sender–receiver task, (ii) the die‐roll task, and (iii) self‐reported honesty levels and account for other‐regarding preferences and social norms to disentangle key alternative motives. We find that all three measures of honesty preferences robustly predict contributions, as do other‐regarding preferences and empirical expectations but not normative expectations. Additionally, honesty preferences predict contributions in the Honesty Frame but not in the Contribution Frame, although the difference between these is not consistently significant. Finally, we find no differences in average cooperation across the treatments.
A comparative study of in vitro dose–response estimation under extreme observations
Authors: Fang Xinying , Zhou Shouhao 
Published: April 2023

AbstractQuantifying drug potency, which requires an accurate estimation of dose–response relationship, is essential for drug development in biomedical research and life sciences. However, the standard estimation procedure of the median–effect equation to describe the dose–response curve is vulnerable to extreme observations in common experimental data. To facilitate appropriate statistical inference, many powerful estimation tools have been developed in R, including various dose–response packages based on the nonlinear least squares method with different optimization strategies. Recently, beta regression‐based methods have also been introduced in estimation of the median–effect equation. In theory, they can overcome nonnormality, heteroscedasticity, and asymmetry and accommodate flexible robust frameworks and coefficients penalization. To identify a reliable estimation method(s) to estimate dose–response curves even with extreme observations, we conducted a comparative study to review 14 different tools in R and examine their robustness and efficiency via Monte Carlo simulation under a list of comprehensive scenarios. The simulation results demonstrate that penalized beta regression using the mgcv package outperforms other methods in terms of stable, accurate estimation, and reliable uncertainty quantification.