bluuebunny/crossref_metadata_2025_split huggingface dataset:
Persuading managers to enact ideas in organizations: The role of voice message quality, peer endorsement, and peer opposition
Authors: Brykman Kyle M. , Raver Jana L. 
Published: March 2023

SummaryWe extend research on employee voice by examining what persuades managers to enact voice messages communicated on organizations' idea management platforms (i.e., software systems designed to gather, vet, and enact employee voice). Applying the elaboration likelihood model of persuasion, we propose that voice message quality affects managerial voice enactment via peer endorsement and that peer opposition qualifies the latter effect. Specifically, we argue that peers are more likely to endorse higher‐ versus lower‐quality voice messages because they are attentive recipients who are motivated to support higher‐quality voice. In turn, we argue that managers are influenced by image concerns and legitimacy inferred by social proof, and thus, they will enact voice messages with higher levels of peer endorsement, especially when combined with lower opposition. Results of our archival analysis of over 5000 voice messages communicated on five organizations' idea management platforms support our predictions, such that peer endorsement mediates the relationship between voice message quality and managerial voice enactment, and that this relationship is stronger under conditions of lower versus higher peer opposition. Altogether, our research illuminates how voice messages on idea management platforms are endorsed and ultimately enacted by organizational leaders.
Effect of fermentation methods on properties of dough and whole wheat bread
Authors: Zeng Fangye , Yang Yueyue , Liu Qing , Yang Jiahua , Jin Zhengyu , Jiao Aiquan 
Published: March 2023

AbstractBackgroundWhole wheat bread is high in nutritional value but poor in technological quality; therefore, research on how to improve its technological quality has attracted extensive attention. The effects of fermentation methods, including straight dough(STD), sourdough (SOD), sponge dough (SPD), and refrigerated SPD (RSD) methods, on the dough and bread quality of whole wheat bread were investigated, focusing on pasting properties, rheological properties, thermal properties, microstructure, basic quality, and starch digestibility.ResultsThe rapid viscosity analysis and rheological results demonstrated that SOD had the highest pasting temperature and the lowest viscosity, indicating an inhibition of starch pasting and partial protein hydrolysis, whereas the opposite trend presented by SPD and RSD indicated a greater starch hydration and a stronger gluten network. Thermal gravimetric analysis and differential scanning calorimetry results indicated reduced starch thermal degradation and increased starch pasting enthalpy in SOD and RSD. Scanning electron microscopy images revealed that the starch granules of SOD and RSD were tightly wrapped by a gluten network. SOD and RSD breads had the largest specific volume, the softest texture, and the lowest glycemic index.ConclusionThe effects of different fermentation methods on dough and bread structure can provide instructive information for future studies on their applications in whole wheat bread production. © 2023 Society of Chemical Industry.
Reflections on establishing an effective and sustainable community of practice for a strategic objective within a higher education institution
Authors: Bastiaens Ellen , Heymann Perry 
Published: March 2023

AbstractCommunities of practice (CoPs) have received much attention since the introduction of this concept in the early nineties. Most CoPs in higher education address teaching and learning for specific subject matter, or professional development focusing on the student or the teacher. In our case study, we developed a CoP around a strategic objective for our institution: addressing the enhancement of the employability of our students. This article presents our investigation of what features are key for an effective and sustainable CoP that facilitates the achievement of a strategic objective in a higher education institution (HEI). We used a case study analysis to identify key ingredients that contribute to establishing an effective and sustainable CoP: (1) installing a core group as catalyst; (2) defining a common language connecting strategy, theory and practice; (3) appointing the facilitator; (4) creating an open atmosphere in and around the community; (5) create close involvement in the CoP with the already‐standing organisation to ensure long‐lasting and sustainable continuation of a CoP. Next to the evaluation of key features for the CoP, we also reflected on design thinking as integral to facilitating the community's practice.
Incidence of asymptomatic SARS‐CoV‐2 infection in children undergoing elective otolaryngologic surgery throughout the COVID‐19 pandemic
Authors: Koh Elizabeth S. , Kacker Ashutosh , Maresh Alison M. , Modi Vikash K. , Rosenblatt Steven D. , Jones Jacqueline E. 
Published: March 2023

AbstractObjectiveChildren infected with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are less clinically affected than adults, with most cases presenting as asymptomatic or mildly symptomatic. However, true rates of asymptomatic SARS‐CoV‐2 infection in children remain unclear. We sought to examine rates of SARS‐CoV‐2 in asymptomatic children and the role of children in transmission.MethodsWe performed a retrospective review of patients between 6 months and 17 years of age who underwent elective or semi‐elective otolaryngologic surgery with physicians affiliated with Weill Cornell Medicine between May 15, 2020 and March 31, 2022. Patients were included if they received molecular assay testing for SARS‐CoV‐2 without SARS‐CoV‐2 symptoms within 5 days of scheduled surgery. SARS‐CoV‐2 infection status, exposure, clinical symptoms, demographic data, and insurance status were recorded.Results1047 patients met inclusion criteria. Thirteen positive cases (1.24%) were identified in the study population. Six cases occurred between December 2021 and February 2022 following the classification of the omicron variant as a variant of concern in November 2021. Five of the 13 cases occurred in children under 2 years of age. Seven patients were male, and five were female. Residences spanned all five boroughs of New York City and the surrounding metropolitan area.ConclusionThroughout the pandemic, children have had a low rate of asymptomatic disease and likely pose a low risk of transmission of SARS‐CoV‐2 to the general population. Our results suggest that testing of asymptomatic children is a low‐yield practice that is unlikely to influence rates of SARS‐CoV‐2 in the general population.Level of Evidence3.
Effects of fatty acid‐ethanol amine (FA‐EA) derivatives on lipid accumulation and inflammation
Authors: Li Mengyu , Huang Xiaoqing , Huang Mengxian , Jin Wenhui , Hong Zhuan , Zhang Yucang , Fang Hua , Chen Weizhu 
Published: March 2023

AbstractThis study aimed to investigate the effect of fatty acid‐ethanol amine (FA‐EA) derivatives (L1–L10) on the mitigation of intracellular lipid accumulation and downregulation of pro‐inflammatory cytokines in vitro. First, the series of FA‐EA derivatives were synthesized and characterized. Then, their cytotoxic, intracellular lipid accumulation and inhibition of pro‐inflammatory cytokines were evaluated. The oil red O staining experiment showed that the tested compounds L4, L6, L8, L9, and L10 could reduce intracellular lipid accumulation induced by palmitic acid (PA). Moreover, ω‐3/ω‐6 PUFA‐EA derivatives showed inhibitory effect on the production of pro‐inflammatory cytokines in lipopolysaccharide (LPS) ‐stimulated RAW 264.7 cells. ω‐3/ω‐6 PUFA‐EA derivatives at a concentrations of 10 μM could significantly decrease mRNA levels of IL‐6, IL‐1β, and TNF‐α, inhibit NO production, and alleviate the protein expression of IL‐1β in lipopolysaccharide (LPS)‐stimulated RAW 264.7 cells. These data suggest that ω‐3 PUFA‐EA derivatives can be beneficial for further pharmaceutical development to treat chronic low‐grade inflammation diseases such as obesity.
All‐Dielectric Huygens’ Meta‐Waveguides for Resonant Integrated Photonics
Authors: Sırmacı Yunus Denizhan , Barreda Gomez Angela , Pertsch Thomas , Schmid Jens H. , Cheben Pavel , Staude Isabelle 
Published: March 2023

AbstractThe growing maturity of nanofabrication technology has recently enabled the deployment of high‐quality subwavelength nanostructures on photonic chips. Combining existing photonic waveguide technology with the paradigms adapted from metamaterials opens new avenues towards unprecedented control of guided light waves. However, developing new functionalities while preserving efficiencies and offering compatibility with current technology remains a major challenge in on‐chip nanophotonics. Here, a novel silicon nanophotonic waveguide comprising a chain of resonantly forward scattering nanoparticles empowered by spectrally overlapping electric and magnetic dipolar Mie‐type resonances is proposed and demonstrated. The propagation loss of the meta‐waveguides in the telecom spectral range is as low as 0.4 dB mm−1, exceeding the current record for Mie‐resonant waveguides by more than an order of magnitude. Furthermore, the meta‐waveguides support a negative group index over a broad spectral range of 60 nm and regions of vanishing and anomalous dispersion within the transmission band. Finally, it is shown that meta‐waveguide topologies can implement compact resonance‐protected waveguide bends and efficient splitters within just 320 nm propagation length. This work addresses the fundamental challenges of miniaturization, dispersion, and scattering control in integrated photonics and opens new opportunities for enhancing light–matter interactions, interfacing nanophotonic components, and developing nonlinear, ultrafast, and quantum optics resonant on‐chip devices.
Assessment of Fibrin‐Based Hydrogels Containing a Fibrin‐Binding Peptide to Tune Mechanical Properties and Cell Responses
Authors: Brinkmann Jannika , Malyaran Hanna , Enezy‐Ulbrich Miriam Aischa Al , Jung Shannon , Radermacher Chloé , Buhl Eva Miriam , Pich Andrij , Neuss Sabine 
Published: March 2023

AbstractFibrin‐based hydrogels are used as scaffolds in tissue engineering and regenerative medicine due to their biocompatibility, low cell toxicity, autologous production, and relevance for wound healing and clot formation. The availability of fibrinogen as well as its unique mechanical behavior exhibiting nonlinear elasticity makes it suitable for the fabrication of hydrogels. However, the broad application of fibrin hydrogels in biomaterials still faces challenges in terms of gel shrinkage and degradation processes. This can be addressed through the modulation of the hydrogels'r chemical and mechanical properties. In the present work, it is demonstrated that fibrin‐based hydrogels with adjustable mechanical properties and controllable degradation profiles can be fabricated through the addition of fibrin‐binding peptides. The cyclic peptide X2CXYYGTCLX (Tn7) is used, binding to fibrin by noncovalent supramolecular interactions. These new hydrogels exhibit no toxicity and reduced degradation rate at the same time supporting cell proliferation. Tn7 peptides significantly increase the Young's Modulus and mechanical stiffness as well as fibrin fiber thickness and inter‐fiber crosslinking in hydrogels. In conclusion, hydrogels with optimized mechanical properties and controllable degradation profiles that can be advantageous for further approaches in tissue regeneration, cell‐based therapies, or clinical treatment options are produced.
Global prevalence of Staphylococcus aureus in food products and its relationship with the occurrence and development of diabetes mellitus
Authors: Liang Tingting , Liang Zhuang , Wu Shi , Ding Yu , Wu Qingping , Gu Bing 
Published: March 2023

AbstractThe worldwide distribution of Staphylococcus aureus across food types is an important food safety concern. This study aimed to estimate the prevalence of S. aureus in food products and its relationship with the occurrence and development of diabetes mellitus. A total of 55 articles were included. The pooled prevalence of S. aureus was 30.2%. The highest prevalence of S. aureus was observed in cereals, followed by meat and bean products, and the lowest in confectionery, egg products, and vegetables. The prevalence in dairy and seafood products was similar. Combinations of culture and molecular methods have been used for S. aureus detection. Furthermore, the prevalence of S. aureus in developed countries (Europe and North America) was higher than that in developing countries (Asia and Africa). In addition, the prevalence was higher in the provinces of Xinjiang and Shaanxi than that in Sichuan and Shandong in China, which may be due to the difference in climate and dietary habits. The results revealed that food type, bacterial detection methods, and location can influence the prevalence of S. aureus contamination. Resistance rates to preferred antibiotics against S. aureus were the highest for cephradine, polymyxin B, and penicillin at 82.9%, 82.0%, and 81.3%, respectively. In addition, 17 studies were system reviewed that the S. aureus infections are closely associated with the development of diabetes, and the treatment of probiotic, prebiotic, FMT, and bacteriophage can prevent and control S. aureus infections. This review emphasizes the high prevalence of S. aureus contamination in food, suggesting a potential diabetic infection risk and importance of observing principles of food safety and hygiene to reduce S. aureus.
Rapamycin encourages the maintenance of mitochondrial dynamic balance and mitophagy activity for improving developmental competence of blastocysts in porcine embryos in vitro
Authors: Park Hyo‐Jin , Heo Gyeong‐Deok , Yang Seul‐Gi , Koo Deog‐Bon 
Published: March 2023

AbstractRapamycin induces autophagosome formation and activity during oocyte maturation, improved fertilization ability of matured oocytes, and early embryonic developmental competence. However, potential changes in mitochondrial fission and mitophagy via regulation of autophagy in early porcine embryonic development have not been previously studied. Here, we investigated embryonic developmental ability and quality of porcine embryos 2 days after in vitro fertilization and following treatment with 1 and 10 nM rapamycin. As a results, 1 nM rapamycin exposure significantly improved (p < 0.05) blastocyst developmental competence compared to that in nontreated embryos (nontreated: 26.2 ± 5.7% vs. 1 nM rapamycin: 35.3 ± 5.1%). We observed autophagic (LC3B) and mitochondrial fission protein expression (dynamin‐related protein‐1 [DRP1] and pDRP1‐Ser616) at the cleavage stage of 1 and 10 nM rapamycin‐treated porcine embryos, using Western blot and immunofluorescence analyses. Interestingly, 1 nM rapamycin treatment significantly improved autophagy formation, mitochondrial activation, and mitochondrial fission protein levels (p < 0.05; p‐DRP1 [Ser616]) at the cleavage stage of porcine embryos. Additionally, mitophagy was significantly increased in blastocysts treated with 1 nM rapamycin. In conclusion, our results suggest that rapamycin promotes blastocyst development ability in porcine embryos through mitochondrial fission, activation, and mitophagy in in vitro culture.
Improved MR temperature imaging at 0.5 T using view‐sharing accelerated multiecho thermometry for MR‐guided laser interstitial thermal therapy
Authors: Pan Ziyi , Liu Simin , Hu Jianxiong , Luo Hai , Han Meng , Sun Hao , Liu Wenbo , Wu Ziyue , Guo Hua 
Published: March 2023

AbstractThe aim of the current study was to improve temperature‐monitoring precision using multiecho proton resonance frequency shift‐based thermometry with view‐sharing acceleration for MR‐guided laser interstitial thermal therapy (MRgLITT) on a 0.5‐T low‐field MR system. Both precision and speed of the temperature measurement for clinical MRgLITT treatments suffer at low field, due to reduced image signal‐to‐noise ratio (SNR), decreased temperature‐induced phase changes, and limited RF receiver channels. In this work, a bipolar multiecho gradient‐recalled echo sequence with a temperature‐to‐noise ratio optimal weighted echo combination is applied to improve the temperature precision. A view‐sharing–based approach is utilized to accelerate signal acquisitions while preserving image SNRs. The method was evaluated using ex vivo (pork and pig brain) LITT heating experiments and in vivo (human brain) nonheating experiments on a high‐performance 0.5‐T scanner. In terms of results, (1) after echo combination, multiecho thermometry (i.e., ~7.5–40.5 ms, 7 TEs) provides ~1.5–1.9 times higher temperature precision than the no echo combination case (i.e., TE7 = 40.5 ms) within the same readout bandwidth. Additionally, echo registration is necessary for the bipolar multiecho sequence; (2) for a threefold acceleration, the view‐sharing approach with variable‐density subsampling shows around 1.8 times lower temperature errors than the GRAPPA method. Particularly for view‐sharing, variable‐density subsampling performs better than Interleave subsampling; and (3) ex vivo heating and in vivo nonheating experiments demonstrated that the temperature accuracy was less than 0.5
and that the temperature precision was less than 0.6
using the proposed 0.5‐T thermometry. It was concluded that view‐sharing accelerated multiecho thermometry is a practical temperature measurement approach for MRgLITT at 0.5 T.
Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function
Authors: Jensen Simon B. K. , Juhl Christian R. , Janus Charlotte , Lundgren Julie R. , Martinussen Christoffer , Wiingaard Christoffer , Knudsen Cecilie , Frikke‐Schmidt Ruth , Stallknecht Bente M. , Holst Jens J. , Madsbad Sten , Torekov Signe S. 
Published: March 2023

AbstractObjectiveThe aim of this study was to investigate glucose tolerance, glucagon response, and beta cell function during a 1‐year maintenance period with either exercise, the glucagon‐like peptide‐1 receptor agonist liraglutide, or the combination after diet‐induced weight loss.MethodsIn this randomized placebo‐controlled trial, adults with obesity (BMI: 32–43 kg/m2) without diabetes underwent an 8‐week low‐calorie diet (800 kcal/d) and were randomized to 52 weeks of aerobic exercise, liraglutide 3.0 mg/d, exercise and liraglutide combined, or placebo. Change in glucose and glucagon response to a 3‐hour mixed meal test and disposition index, as a measure of beta cell function, were measured.ResultsA total of 195 participants were randomized. After 1 year of treatment, the combination group had decreased postprandial glucose response by −9% (95% CI: −14% to −3%; p = 0.002), improved beta cell function by 49% (95% CI: 16% to 93%; p = 0.002), and decreased glucagon response by −18% (95% CI: −34% to −3%; p = 0.024) compared with placebo. Compared with placebo, liraglutide alone improved postprandial glucose response by −7% (95% CI: −12% to −1%; p = 0.018), but not beta cell function or glucagon. Exercise alone had similar postprandial glucose response, beta cell function, and glucagon response as placebo.ConclusionsOnly the combination of exercise and liraglutide improved glucose tolerance, beta cell function, and glucagon responses after weight loss.
The development and evaluation of a vaccination pathway for children with intellectual and developmental disability and needle fear
Authors: Ong Natalie , Brogan Deidre , Lucien Abbie , Wolman Shayna , Campbell Denise , Deng Lucy , Koirala Archana , Garg Pankaj , Sharma Ketaki 
Published: March 2023

AbstractThis qualitative study describes the development and evaluation of a clinical pathway to facilitate the implementation of catch‐up vaccinations for children with significant needle fear, particularly in children with developmental disabilities. The Specialist Immunization Team, based at a tertiary level teaching children's hospital, participated in process mapping activities using Motivational Interviewing (MI) techniques and reflective discussions. Team members developed a clinical pathway by incorporating parental feedback from semistructured interviews and clinical expertise from within the team, facilitated by colleagues from the Child Development Unit. A process map was developed that included process strengths and touch points with an action plan that was discussed and agreed upon. A repeat process mapping activity was conducted 16 months later. Reports from parental feedback included: positive, efficient, and successful experiences of having their child undergo catch‐up vaccinations. The experience empowered families for further procedures. Team members reported improvements in triaging appropriate children for the pathway, and an increase in confidence to interact and manage behaviors of children with significant anxiety and challenging behaviors. They also reported an increase in successful vaccinations with improved clinical judgment of facilitating the sedation pathway. This study demonstrates that using group facilitation using motivational interviewing in reflective discussions and process mapping utilizing parent and staff feedback in service improvement activities results in efficient and successful service delivery with improved patient outcomes.
Functional characterization of five developmental signaling network genes in the white‐backed planthopper: Potential application for pest management
Authors: Liu Xuan‐Zheng , Guo Huan , Long Gui‐Jun , Ma Yun‐Feng , Gong Lang‐Lang , Zhang Meng‐Qi , Hull J Joe , Dewer Youssef , Liu Li‐Wei , He Ming , He Peng 
Published: March 2023

AbstractBACKGROUNDThe white‐backed planthopper (WBPH, Sogatella furcifera) is a major rice pest that exhibits condition dependent wing dimorphisms – a macropterous (long wing) form and a brachypterous (short wing) form. Although, the gene cascade that regulates wing development and dimorphic differentiation has been largely defined, the utility of these genes as targets for pest control has yet to be fully explored.RESULTSFive genes typically associated with the developmental signaling network, armadillo (arm), apterous A (apA), scalloped (sd), dachs (d), and yorkie (yki) were identified from the WBPH genome and their roles in wing development assessed following RNA interference (RNAi)‐mediated knockdown. At 5 days‐post injection, transcript levels for all five targets were substantially decreased compared with the dsGFP control group. Among the treatment groups, those injected with dsSfarm had the most pronounced effects on transcript reduction, mortality (95 ± 3%), and incidence (45 ± 3%) of wing deformities, whereas those injected with dsSfyki had the lowest incidence (6.7 ± 4%). To assess the utility of topical RNAi for Sfarm, we used a spray‐based approach that complexed a large‐scale, bacteria‐based double‐stranded RNA (dsRNA) expression pipeline with star polycation (SPc) nanoparticles. Rice seedlings infested with third and fourth instar nymphs were sprayed with SPc–dsRNA formulations and RNAi phenotypic effects were assessed over time. At 2 days post‐spray, Sfarm transcript levels decreased by 86 ± 9.5% compared with dsGFP groups, and the subsequent incidences of mortality and wing defects were elevated in the treatment group.CONCLUSIONSThis study characterized five genes in the WBPH developmental signaling cascade, assessed their impact on survival and wing development via RNAi, and developed a nanoparticle‐dsRNA spray approach for potential field control of WBPH. © 2023 Society of Chemical Industry.