bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of E 472b emulsifiers in foamed food formulations by high-performance thin-layer chromatography‒fluorescence detection
Authors: Schuster Katharina , Blankart Max , Wagner Melanie , Tritschler Daniel , Hinrichs Jörg , Granvogl Michael , Oellig Claudia 
Published: December 2022

AbstractE 472b emulsifiers, defined as lactic acid esters of mono- and diacylglycerides, are food emulsifiers widely used in foamed food formulations. So far, only qualitative methods for analyzing E 472b emulsifiers have been published. Thus, a new method was developed for determining E 472b in different foamed food formulations by high-performance thin-layer chromatography with fluorescence detection (HPTLC‒FLD). The proposed method allows simple and fast E 472b emulsifier extraction from the food matrix and points out an analytical approach for quantifying these emulsifiers using a commercial E 472b emulsifier as the reference standard. Limits of decision with 56‒59 ng of E 472b emulsifier/zone and limits of quantification with 172‒179 ng of E 472b emulsifier/zone in three foamed model food formulations, respectively, as well as satisfactory repeatability (n = 6) and reproducibility (n = 6) exposed by low relative standard deviation < 8% proved the method suitable for the sensitive and reliable determination of E 472b emulsifiers. Recoveries between 96 and 109.3% were obtained for all investigated model systems. In commercial foamed food formulations from the German market, the E 472b emulsifier content ranged between 0.1 and 0.6 g/100 g.
Synthesis of N-isopropyl acrylamide copolymerized acrylic acid caped with Dibenzo-18-crown-6 composite for selective separation of Co-60 radioisotope from radioactive liquid waste containing Cs-137
Authors: Hassan Reham S. , Rizk Soad Elsayed , Hamed Mahmoud G. 
Published: December 2022

AbstractA new selective polymeric composite capped with crown ether was successfully synthesized using N-isopropyl acrylamide copolymerized acrylic acid paired with Dibenzo-18-crown-6, P(NIPAm-Co-AA-DB 18C-6), by Gamma irradiation and ultrasonic homogenizer polymerization. Scanner electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and dynamic light scattering were used to characterize the selected polymeric composite's chemical and physical constitution. SEM shows a rough irregular surface, and FTIR spectra confirmed the function groups of P(NIPAm-Co-AA-DB 18C-6). Moreover, a systematic study of monomer and crown ether concentration was investigated to enhance the composite's performance. The behavior of the synthetic composite toward the selective separation of Co-60 from Cs-137 in a binary system was evaluated. Effects of pH, contact time, and initial ion concentration were investigated in a batch mode and the maximum capacity reached 108.0 mg/g for Co-60 and 82.0 mg/g for Cs-137. Four Kinetic models were investigated (pseudo-first-order, pseudo-second-order, Elovich, and Intra-particle diffusion). Regarding the calculated parameters, pseudo-second-order and Elovich models are the most describing the sorption process, indicating the chemisorptions process. Six adsorption isotherms were examined, two-parameter models (Langmuir, and Freundlich) and three-parameter models (Redlich-Peterson, Khan, Sips, and Hills). The best-fitted isotherm was identified using three error methodological approaches: the correlation coefficient (R2), the chi-square test (χ2), and the root-mean-square error. Isotherm models fit the experimental values in the following sequence: Khan > Rdlish-Peterson > Hills > Sips. Finally, an application for column separation was conducted, and Co-60 was completely separated from Cs-137 by 0.1 M HNO3. These findings indicate promising applications in the successive separation of Co-60 from radioactive liquid waste containing Cs-137 from Egyptian reactors.
Graphical abstract
Assessment and application of optical flow in background-oriented schlieren for compressible flows
Authors: Cakir Bora O. , Lavagnoli Sergio , Saracoglu Bayindir H. , Fureby Christer 
Published: December 2022

Abstract
Optical flow provides an opportunity to elevate the resolution and sensitivity of deflection sensing in background-oriented schlieren (BOS). Despite extensive relevant literature within the field of computer vision, there is a lack of proper quantification of its abilities and limitations with regard to the state-of-the-art BOS experiments. Thus, this study performs an assessment of accuracy and resolution limits in different flow field scenarios utilizing background patterns generated with random dot and wavelet noise distributions. Accordingly, a synthetic assessment over a theoretically generated Prandtl–Meyer expansion fan is conducted with variations introduced in the background patterns and operational parameters of optical flow. A clear superiority of accuracy and resolvable range of density gradient amplitudes over cross-correlation is demonstrated. Moreover, an experimental assessment of supersonic flow features over multiple wind tunnel models is performed. The influence of experimental constraints, limitations and uncertainties related to the application of optical flow in BOS and its comparative performance against the block-matching counterpart is characterized.

Graphical abstract
Robust Design of 3D-Printed W-Band Bandpass Filters Using Gap Waveguide Technology
Authors: Santiago David , Tamayo-Domínguez Adrián , Laso Miguel A. G. , Lopetegi Txema , Fernández-González José-Manuel , Martínez Ramón , Arregui Iván 
Published: December 2022

AbstractIn this paper, a W-band 3D-printed bandpass filter is proposed. The use of higher-order TE10n modes in groove gap waveguide (GGW) technology is evaluated in order to alleviate the manufacturing requirements. In addition to the use of higher-order modes, the coupling between them is analyzed in detail to improve the overall fabrication robustness of the component. This allows the implementation of narrow-band filters operating at millimeter-wave frequency bands (or above), which usually demand complex manufacturing techniques to provide the high accuracy required for this kind of devices. In order to show the applicability of the proposed method, a narrow-band 5th-order Chebyshev bandpass filter centered at 94 GHz, which can be easily fabricated by state-of-the-art stereolithographic (SLA) 3D-printing techniques followed by silver coating, is shown. Excellent measured performance has been obtained.
Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
Authors: Abo-El Fetoh Mohammed E. , Abdel-Fattah Maha M. , Mohamed Wafaa R. , Ramadan Laila A. A. , Afify Hassan 
Published: December 2022

Abstract
Objective and design
Prostatic inflammation is the driving force in benign prostatic hyperplasia (BPH). This work investigated the potential modulatory effect of COX-2 inhibition on ADAM-17/EGFR/ERK1/2 axis.

Materials or subjects
Adult male Wistar rats were used.

Treatment
Celecoxib (10 and 20 mg/kg; i.p.) was injected i.p. daily for three weeks. Testosterone (TST) (3 mg/kg; s.c.) was used to induce BPH.

Methods
Prostatic inflammation and hyperplasia were assessed by organ weight and histopathology. Inflammatory mediators were measured using ELISA technique. Protein analysis was performed using western blotting and immunohistochemistry. Gene expression analysis was performed using qRT-PCR. Statistical analyses included one-way ANOVA and Tukey’s multiple comparison test.

Results
Testosterone-treated rats had a marked increase in COX-2, prostate weight, and index. Moreover, TST-induced COX-2 was inferred from cytoskeletal changes and was attributable to the overexpression of PGE2, NF-κB (p65), and IL-6. COX-2-derived PGE2 increased the activity of ADAM-17, TGF-α, and TNF-α. Consequently, EGFR–ERK1/2 pathway was over-activated, disrupting anti-apoptotic Bcl-2, cyclin D1, and pro-apoptotic Bax. Celecoxib reversed these effects.

Conclusion
COX-2 stimulates the ERK1/2 pathway via PGE2–ADAM-17-catalyzed shedding of TGF-α in testosterone-induced BPH. The results indicate a functional correlation between inflammation and hyperplasia in BPH.
Interlocking metasurfaces
Authors: Bolmin Ophelia , Young Benjamin , Leathe Nicholas , Noell Philip J. , Boyce Brad L. 
Published: January 2023

AbstractInterlocking metasurfaces (ILMs) are architected arrays of mating features that enable joining of two bodies. Complementary to traditional joining technologies such as bolts, adhesives, and welds, ILMs combine ease of assembly, removal, and reassembly with robust mechanical properties. Structural in nature, they act in a quasi-continuous manner across a surface and enable joining of complex surfaces, e.g., lattices. In this perspective, we define an ILM, begin exploring the design domain and illustrate its breath, and pragmatically evaluate mechanical performance and manufacturability. ILMs will find applications in various fields from aerospace to micro-robotics, civil engineering, and prosthetics.
Influence of PBS, PBAT and TPS content on tensile and processing properties of PLA-based polymeric blends at different temperatures
Authors: Dmitruk Anna , Ludwiczak Joanna , Skwarski Mateusz , Makuła Piotr , Kaczyński Paweł 
Published: January 2023

AbstractPLA-based blends were prepared with different ratios of PBS, PBAT and TPS additives to adjust their mechanical and processing properties in various temperatures ( − 20 °C, 0 °C, 20 °C, 40 °C). Biodegradable polymeric specimens were obtained by preliminary extrusion and subsequent injection molding. Tensile properties, e.g., tensile strength, elongation at break, Young’s modulus and yield strength were evaluated. Next, melt flow and melt volume ratios were established. Softening, glass transition, cold crystallization and crystallization temperatures were determined with the use of the DSC method. Heat Deflection Temperatures for 1.8 MPa (HDT A) and 8 MPa (HDT C), as well as Vicat Softening Temperatures at 10 N (VST A) and 50 N (VST B), were examined. The manufacturing method was intentionally simplified to eliminate the need for additional mixture’s modification with compatibilizers. Each of the ductile compounds enhanced the deformability of PLA—most significantly in the case of PBAT and TPS, while at the same time reducing its tensile strength. The effect of the test conditions (strain rate and temperature) on the specimens was evaluated in order to determine the stability of the manufactured blends in dependence on these parameters.
Recent trends on biomaterials for tissue regeneration applications: review
Authors: Farag Mohammad M. 
Published: January 2023

AbstractTissue engineering is approach of replacing or regeneration of biological functions of tissues or organs by using combination of biomaterials, biomolecules and cells. Tissue engineering mainly depends scaffold biomaterials and scaffold fabrication methods. Therefore, there have been progressive investigation and development of new biomaterials with different formulations to help and achieve necessary requirements in the tissue engineering applications. This review is briefly representing necessary features associated with biomaterial type and design required for tissue regeneration applications, and presenting earlier research in tissue engineering field and new trends for future implementation. It is mainly focusing on generations of biomaterials and discovery tissue engineering field. As well as, different types of biomaterials, such as bioceramics, bioactive glasses, synthetic and natural polymers and their derived composites, used in fabrication of scaffolds (as a main part of tissue engineering) are demonstrated in this review. Scaffold fabrication methods are also reviewed here. Moreover, it is showing the recent achievements in tissue engineering field for bone, skin, cartilage, neural, and cardiac regeneration as a pre-clinical procedure for repair of injured and diseased tissues and organs. Finally, recent trends and challenges of biomaterials for tissue regeneration are presented also in this review.Graphical abstract
Thermal volatilisation analysis of graphite intercalation compound fire retardants
Authors: Muir Kellie , Liggat John J. , O’Keeffe Luke 
Published: January 2023

AbstractThermally expandable graphites are becoming increasingly popular as intumescent fire retardants for polymeric systems due to their excellent thermal and barrier properties. Therefore, it is important to understand their thermal degradation pathways and monitor products for any that may be toxic or affect the stability of the polymer. Here, two commercially available thermally expandable graphites with different intercalated acids have been analyzed using thermal volatilisation analysis—sub-ambient distillation (TVA-SAD), mass spectrometry (MS) and Fourier transform infrared spectroscopy (FTIR). Results confirm the presence of three principal thermal events relating to the expansion of graphite nitrate and graphite bisulfate. Isothermal analyses provide a deeper understanding of the processes and decomposition products released from each stage. For both graphites, desorption of migrating gases and volatilisation of water occur in the first instance. Graphite bisulfate releases CO2, CO, and water upon expansion and releases a significant volume of SO2 subsequently. Graphite nitrate expansion proceeds with the release of NO2, NO, CO and water. Additionally, the release of non-condensable species and carbonyl-derived fragments suggests that the exfoliation process occurs by multiple different degradation processes. For expansion to occur, sufficient pressure must be produced in the graphite interlayer spacing; this is achieved by volatilisation of intercalated species and by the decomposition of functional groups on the outer edges and basal planes created from the oxidation of graphite.
Metal tolerance gene family in barley: an in silico comprehensive analysis
Authors: Tanwar Umesh Kumar , Stolarska Ewelina , Rudy Elżbieta , Paluch-Lubawa Ewelina , Grabsztunowicz Magda , Arasimowicz-Jelonek Magdalena , Sobieszczuk-Nowicka Ewa 
Published: December 2022

Abstract
Metal-tolerance proteins (MTPs) are divalent cation transporters that play critical roles in metal tolerance and ion homeostasis in plants. However, a comprehensive study of MTPs is still lacking in crop plants. The current study aimed to comprehensively identify and characterize the MTP gene family in barley (Hordeum vulgare, Hv), an important crop. In total, 12 HvMTPs were identified in the barley genome in this study. They were divided into three phylogenetic groups (Zn-cation diffusion facilitator proteins [CDFs], Fe/Zn-CDFs, and Mn-CDFs) and further subdivided into seven groups (G1, G5, G6, G7, G8, G9, and G12). The majority of MTPs were hydrophobic proteins found in the vacuolar membrane. Gene duplication analysis of HvMTPs revealed one pair of segmental-like duplications in the barley genome. Evolutionary analysis suggested that barley MTPs underwent purifying natural selection. Additionally, the HvMTPs were analyzed in the pan-genome sequences of barley (20 accessions), which suggests that HvMTPs are highly conserved in barley evolution. Cis-acting regulatory elements, microRNA target sites, and protein–protein interaction analysis indicated the role of HvMTPs in a variety of biological processes. Expression profiling suggests that HvMTPs play an active role in maintaining barley nutrient homeostasis throughout its life cycle, and their expression levels were not significantly altered by abiotic stresses like cold, drought, or heat. The expression of barley HvMTP genes in the presence of heavy metals such as Zn2+, Cu2+, As3+, and Cd2+ revealed that these MTPs were induced by at least one metal ion, implying their involvement in metal tolerance or transportation. The identification and comprehensive investigation of MTP gene family members will provide important gene resources for the genetic improvement of crops for metal tolerance, bioremediation, or biofortification of staple crops.
On multivariable Plancherel–Pólya inequality and truncation error upper bounds in irregular sampling
Authors: Pogány Tibor K. 
Published: December 2022

AbstractIn the note is shown that for thed-dimensional Bernstein functions class$$B_{\varvec{\sigma },d}^p,\, p>0$$Bσ,dp,p>0the Plancherel–Pólya inequality holds with the constant which equals to the product of the constants occuring in the one-dimensional cases. Related truncation error upper bounds are precised in the irregular sampling restoration of functions in several variables.
Deep ultraviolet hydrogel based on 2D cobalt-doped titanate
Authors: Xu Youan , Ding Baofu , Huang Ziyang , Dai Lixin , Liu Peng , Li Bing , Cai Wei , Cheng Hui-Ming , Liu Bilu 
Published: January 2023

AbstractBirefringent optical elements that work in deep ultraviolet (DUV) region become increasingly important these years. However, most of the DUV optical elements have fixed birefringence which is hard to be tuned. Here, we invent a birefringence-tunable optical hydrogel with mechano-birefringence effect in the DUV region, based on two-dimensional (2D) low-cobalt-doped titanate. This 2D oxide material has an optical anisotropy factor of 1.5 × 10–11 C2 J−1 m−1, larger than maximum value obtained previously, leading to an extremely large specific magneto-optical Cotton-Mouton coefficient of 3.9 × 106 T−2 m−1. The extremely large coefficient enables the fabrication of birefringent hydrogel in a small magnetic field with an ultra-low concentration of 2D oxide material. The hydrogel can stably and continuously modulate 303 nm DUV light with large phase tunability by varying the strain (compression or stretching) from 0 to 50%. Our work opens the door to design and fabricate new proof-of-concept DUV birefringence-tunable element, as demonstrated by optical hydrogels capable of DUV modulation by mechanical stimuli.
Light People: Professor Guangcan Guo
Authors: Wang Hui 
Published: January 2023

EditorialThe Nobel Prize in Physics 2022 was awarded to French physicist Alain Aspect, American physicist John F. Clauser, and Austrian physicist Anton Zeilinger, in recognition of their contributions to the research of quantum information, a clear indication that we are entering the era of quantum information.In China, a scientist has played herald in quantum research since as early as the 1980s. He introduced quantum optics and quantum informatics to China, a virgin land in terms of quantum research back then. That scientist is Academician Guangcan Guo.Out of personal interests and his good sense as a scientist, Prof. Guo took it upon himself to take on quantum optics when little was known about it in China. He trained many students and launched China’s first academic conference on quantum optics, which helped to accelerate the development of quantum optics in China.In the early 1990s, he took on another challenge, shifting his research focus to the emerging subject of quantum informatics. His work helped to establish China’s current leading position in this interdisciplinary field. Today, China leads the world in quantum USB drives and quantum chips.Now in his 1980s, Prof. Guo is still working tirelessly at the front line of scientific research, doing science popularization, and teaching students. He is ready for the third big challenge of his life—to reveal the mysteries of the classical world and the quantum world.Next, please follow “Light People” into the mysterious “quantum world”, and feel the beauty of science.
Dose-dependent biological toxicity of green synthesized silver nanoparticles in rat’s brain
Authors: Tareq Mai , Khadrawy Yasser A. , Rageh Monira M. , Mohammed Haitham S. 
Published: December 2022

AbstractMetal nanoparticles, in general, and silver nanoparticles (AgNPs), in particular, have been the focus of numerous studies over the last two decades. Recently, the green synthesis of metal nanoparticles has been favored over chemical synthesis due to its low toxicity and easy preparation. The present study aims to investigate the dose-dependent toxicity of green synthesized AgNPs on rats’ brains. Thirty-four Wistar male rats were divided into four groups. The first, second, and third groups were administered for 14 days with three different doses (0.5, 5, and 10 mg/kg) of AgNPs, respectively. The fourth group, which served as a control group, was given normal saline for the same period. The toxicity of the green synthesized AgNPs on the cortical and hippocampal levels of the oxidative stress markers (MDA, NO, and GSH) as well as the activity of acetylcholinesterase (AchE) and the monoamine neurotransmitters (DA, NE, and 5H-T) were investigated. AgNPs showed minimal oxidative stress in the cortex and hippocampus for the administered doses. However, AgNPs showed an inhibitory effect on AchE activity in a dose-dependent manner and a decrease in the 5H-T and NE levels. The green synthesized AgNPs showed an ultrastructural change in the cellular membranes of the neurons. The green synthesis of AgNPs has reduced their cytotoxic oxidative effects due to their capping with biologically compatible and boosting molecules such as flavonoids. However, another neurotoxicity was observed in a dose-dependent manner.
Effects of paraprobiotic as replacements for antibiotic on performance, immunity, gut health and carcass characteristics in broiler chickens
Authors: Tukaram Nampalle Mukesh , Biswas Avishek , Deo Chandra , Laxman Agashe Jayanti , Monika Madheshwaran , Tiwari Ashok Kumar 
Published: December 2022

AbstractThis study sought to determine the effects of dietary paraprobiotic (PPB) on broiler chicken performance, immunity, gut health, and carcass traits. A total of 240 day-old CARIBRO Vishal commercial broiler chicks of identical body weight randomly divided into six treatment groups, each with five replicates and eight chicks in each replicate. Six dietary treatments were preapared: T1 = (control diet), T2 = T1 + 0.02% (w/v) chlortetracycline (CTC), T3 = T1 + 0.2% (w/v) PPB, T4 = T1 + 0.4% (w/v) PPB, T5 = T1 + 0.6% (w/v) PPB and T6 = T1 + 0.8% (w/v) PPB, respectively. Body weight gain (BWG) significantly (P ≤ 0.05) increased in the T5 (0.6% PPB) and T6 (0.8% PPB) group. At the same time the feed intake significantly (P ≤ 0.05) decreased and the feed conversion ratio (FCR) significantly (P ≤ 0.05) improved in T5 and T6 group. There was a significant (P ≤ 0.05) increase in cell-mediated immunity and haem-agglutination titre (HA titre) in the 0.6% and 0.8% PPB supplemented groups compare to the control group (T1). The percentage of carcass traits and organ weights did not significantly differ between the PPB-supplemented and control groups, but the percentage of live weight in cut up parts showed a significant improvement (P ≤ 0.05) in the PPB-supplemented group. At 42 days, villus height, width, and crypt depth all significantly (P ≤ 0.05) increased in the groups supplemented with 0.6 and 0.8% para-probiotics (T5 and T6). The results show that para-probiotics can be added to broiler diets at a rate of 0.6% (w/v) to enhance performance, immunity, gut health, and breast yield. The para-probiotic may therefore be a useful substitution for antibiotic growth promoters in the diet of chickens.