bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wnt and BMP signalling direct anterior/posterior differentiation in aggregates of mouse embryonic stem cells
Authors: Amel Atoosa , Rossouw Simoné , Goolam Mubeen 
Published: April 2023

AbstractStem cell-based embryo models have allowed greater insight into peri-implantation mammalian developmental events that are otherwise difficult to manipulate due to the inaccessibility of the early embryo. The rapid development of this field has resulted in the precise roles of frequently used supplements such as N2, B27 and Chiron in driving stem cell lineage commitment not being clearly defined. Here, we investigate the effects of these supplements on embryoid bodies to better understand their roles in stem cell differentiation. We show that Wnt signalling has a posteriorising effect on stem cell aggregates and directs differentiation towards the mesoderm, as confirmed through the upregulation of posterior and mesodermal markers. N2 and B27 can mitigate these effects and up-regulate the expression of anterior markers. To control the Wnt gradient and the subsequent anterior vs. posterior fate, we make use of a BMP4 signalling centre and show that aggregates in these conditions express cephalic markers. These findings indicate that there is an intricate balance between various culture supplements and their ability to set up the anterior/posterior axis in stem cell embryo models.Summary StatementThe complex reagents used in ’stembryo’ protocols have unclear roles in stem cell differentiation in vitro requiring further investigation. This study examines their effects on embryoid bodies.
metaGraphos: a Web-based system for transcribing, proofreading and publishing scanned documents
Authors: Varthis Evagelos , Poulos Marios 
Published: April 2023

PurposeThis study aims to present metaGraphos, a crowdsourcing system that aids in the transcription and semantic enhancement of scanned documents by using a pool of volunteers or people willing to participate in exchange for a financial reward.Design/methodology/approachThe metaGraphos can be used in circumstances where optical character recognition fails to produce satisfactory results, semantic tagging or assigning thematic headings to texts is considered necessary or even when ground-truth data has to be collected in raw form.FindingsThe system automatically provides a Web-based interface comprising a static HTML page and JavaScript code that displays the scanned images of the document, coupled with the corresponding incomplete texts side by side, allowing users to correct or complete the texts in parallel.Social implicationsBy assisting the parallel transcription and the semantic enhancement of difficult scanned documents, the system further reveals the hidden cultural wealth and aids in knowledge dissemination, a fact that contributes significantly to the academic-scientific dialog and feedback.Originality/valueIndividual researchers, libraries and organizations in general may benefit from the system because it is cost-effective, practical and simple to set up client–server architecture that provides a reliable way to transcribe texts or revise transcriptions on a large scale.
Social inclusion of disabled performers in the performing arts: a case from Türkiye
Authors: Collins Ayse , Fillis Ian , Sanal Zeynep Goknil 
Published: April 2023

PurposeThe purpose of this paper is to develop an understanding for the social inclusion of disabled performers in a developing country to create awareness and improve policies/practices.Design/methodology/approachThe study employed qualitative methodology, and data were collected through semi-structured interviews, site visits/observations and review of secondary data.FindingsThe data from different respondent groups showed the social inclusion should be reviewed at three levels: the state, society and individual. The review of existing policies revealed the neglect of the state regarding disabled people in general and even more so in performing arts due to the lack of enforcement of national and international agreements. Findings indicate that social inclusion of disabled performers is a minor issue, especially in a developing country where access to basic human rights and needs may be difficult. Amidst such difficulties, performing arts is not seen as a priority compared to other needs of disabled people and performers.Research limitations/implicationsLimitations include the limited number of disabled performers who could be identified and were willing to participate in the study. Those working in venues/public offices were also reluctant to participate. The greatest limitation was the broad lack of interest in disabled performers.Originality/valueIn Türkiye, studies on disabled people tend to focus on basic needs like health, education and employment. None, to best of researchers' knowledge, explore the social inclusion of disabled performers. This is an original study because it collects and discusses primary data on this topic, revealing the state-level negligence/oversight, the apathy of society and the degree to which an individual with disabilities must struggle to participate in performing arts. Consequently, this study shows the difficulty of developing social inclusion, equality and diversity in an emerging economy for disabled performers to raise awareness and present grounds for further legal enforcement. Moreover, implications allow for a global understanding of social inclusion that moves beyond a biased or privileged understanding/critique of disability centered on the developed world.
Studies of China's international aid to education: a systematic review of literature
Authors: Jiang Xiaoying , Holst John D. 
Published: April 2023

PurposeThe purpose of this study is to conduct a systematic review of the literature addressing international aid to education, primarily focusing on China's aid principles and its practice of scholarship programs and short-term training held in higher education institutions (HEIs).Design/methodology/approachUsing the systematic review approach, the authors identified 25 English-language articles in the academic databases. The review is driven by the analytical lenses of (a) the policy formulation and implementation of China's educational aid across macro-, meso- and micro-levels and (b) theories and methodologies that are commonly adopted in the existing studies.FindingsThe review identified three themes: (a) China's aid discourse in the international aid landscape, (b) critical reflections on educational aid program management and (c) international students' study experiences and perceptions of China. The authors also outline prevalent theories and methodological approaches used in the existing literature.Research limitations/implicationsThis literature review provides a review of research on China's international aid to education in the past 20 years, as a frequently cited example of emerging donors that have taken alternative aid approaches, thus bringing about a broader and nuanced perspective of aid to education. It also generates implications for researchers who are interested in studying education and development in the global context.Originality/valueThis study provides is first systematic literature review of studies on international aid to education provided by emerging donors, taking China as an example, to summarize its aid principles and aid practice in China's HEIs.
Information consolidation and repackaging for augmented reality library service: a special reference to the Layar app
Authors: Kharat Santosh Abaji , Nagarkar Shubhada , Panage Bhausaheb 
Published: April 2023

Purpose
The purpose of this research is to introduce the Layar augmented reality (AR) application among library users and to understand the user’s satisfaction towards the information services provided by the Layar application with the help of the structural equation model (SEM).

Design/methodology/approach
According to Thomas (2016), action research is mainly undertaken to develop new skills or new approaches and to solve issues and problems with direct application to any applied setting. The present study helps to develop new skills and approaches to repackaging information using AR applications. Researchers have identified the question of what could be done to increase the awareness of Layar AR applications among students. Because the Layar augmented application is one of the new tools for an academic library to repackage information for mass accessibility. Therefore, in the present action research approach, researchers encompass two activities action and research. Researchers have used participatory action research methods by collecting data from 17 MBA institute libraries affiliated with Savitribai Phule Pune University. Researchers have systematically used the Layar application in the library by obtaining permission from each higher authority. Researchers have designed a Layar satisfaction model using the SEM with AMOS and SPSS.

Findings
The researcher found that the relationship between experience, performance and service quality is positively significant. The user’s experience is satisfied with the Layar application, but users are not satisfied with the service quality and performance of the Layar application.

Research limitations/implications
This study tested Layar AR application in MBA libraries affiliated with Savitribai Phule Pune University in the Pune and Pimpri Chinchwad areas.

Practical implications
The Layar app helps the academic library to convert selected print collections into an AR feel for library users. This is an additional method of providing information services to users through mobile devices. A total of 157 students downloaded the Layar application from their handsets and provided feedback through a questionnaire. Researchers have found that the relationships between users and Layar experience, performance and service quality are positively significant. The user experience is satisfied with the Layar application, but users are not satisfied with the service quality and performance of the Layar application.

Originality/value
This study examined the performance, service quality and user experience of Layar applications. Structural equation and Modelling theories were used to examine the relationship between user satisfaction and information services using the Layar application.
Factors affecting the development of Lipu Yi costumes: intangible cultural heritage tourism
Authors: Fu Xiaohua , Sittithai Thanawan , Chankoson Thitinan 
Published: April 2023

PurposeThe primary purpose of this study is to investigate the influence of tourists' perceived value, satisfaction and behavioral intention on the development of Lipu Yi costume culture to promote the development of intangible cultural tourism and better construct a model of the influencing factors of Lipu Yi costumes in the development of intangible cultural heritage tourism.Design/methodology/approachThe study site is the intangible cultural district of Panzhihua, Sichuan Province, China. This study examines the interrelationships between tourists' perceived value of experience, behavioral intention and satisfaction as the tourists relate to Lipu Yi costume and intangible cultural heritage tourism. A sample of 225 tourists who had visited Panzhihua at least once was selected for the study.FindingsAll seven of the survey's hypotheses were supported. Therefore, this study concludes that tourists' perceived value, satisfaction and behavioral intention directly affect the development of intangible cultural tourism and significantly positively impact the growth of Lipu Yi costumes culture. Descriptive analysis, confirmatory factor analysis (CFA) and structural equation modeling (SEM) investigation methods were used.Originality/valueThis paper analyzes tourists' perceived value of Lipu costume culture and tourists' satisfaction and behavioral intention during the tourism process. This study provides a more in-depth understanding of the relationship between Lipu Yi costume and non-heritage tourism factors. Practical methods and approaches are sought to further develop Lipu Yi costume non-heritage tourism.
Workplace spirituality and entrepreneurial behavior among employees in organizations: the role of psychological ownership
Authors: Delle Meba Tadesse , Segaro Ethiopia Legesse 
Published: April 2023

Purpose
This study aims to understand the mechanisms through which workplace spirituality affects employees’ entrepreneurial behavior. It proposes and tests a mediation model in which psychological ownership (PO), a feeling of ownership regardless of legal ownership, mediates the relationship between workplace spirituality and employees’ entrepreneurial behavior.

Design/methodology/approach
An empirical analysis was conducted with survey data collected from 351 postgraduate students who were also currently working. Structural equation modeling was applied to test the study hypotheses using Mplus software.

Findings
Workplace spirituality is associated with employees’ entrepreneurial behavior, and PO fully mediates this relationship. The findings highlight that PO is the missing link that connects workplace spirituality and employees’ entrepreneurial behavior.

Practical implications
This study offers organizations a new insight by showing that PO plays a key role in contributing to the entrepreneurial behavior of employees who consider themselves spiritual.

Originality/value
The mechanism for the relationship between workplace spirituality and employees’ entrepreneurial behavior is explained.
Investigating the effects of corporate social responsibility on customer citizenship behavior with the mediating roles of corporate image and perceived service quality
Authors: Norouzi Hossein , Teimourfamian Asl Roghayeh 
Published: April 2023

Purpose
The purpose of this study is to measure the effect of initiating corporate social responsibility (CSR) in a service-based company (Pasargad Bank in Tehran) on customers' extra-role behaviors, known as customer citizenship behavior (CCB). The mediating roles of perceived service quality (PSQ) and corporate image (CI) are measured in this model to find out whether they foster this relationship or not.

Design/methodology/approach
This study has been conducted on Iranian Pasargad Bank customers. This study is an empirical study using the questionnaire survey method. Structural equation modeling is used to measure the research framework.

Findings
It is revealed that the PSQ has a partial and positive effect on CCB. Moreover, the variance accounted for index has been used to examine the mediating roles of PSQ and CI in the model of this study. Furthermore, according to the results, CSR positively and directly affects CCB. Among the mediators, PSQ is a partial mediator in the relationship between CSR and CCB. On the other hand, CI was found not to be a mediator in the mentioned relationship in this study.

Originality/value
Studying PSQ would give a broader insight into service providers initiating CSR activities and their outcomes as CCB. Linking the service industry and citizenship behavior would enlighten researchers and service providers to improve their levels of standards.
Connecting transformative luxury with individual and collective well-being: a conceptual approach
Authors: Séraphin Hugues , Yallop Anca C. , Kennell James 
Published: April 2023

PurposeThe tension between individual and collective well-being is at the core of the macromarketing perspective, and transformative luxury research (TLR) has recently begun to consider this in the context of luxury consumption. This conceptual paper reviews TLR in the setting of the tourism and hospitality industry.Design/methodology/approachThe study is based on a literature review in the field of marketing and tourism management.FindingsThe authors propose a TLR–management model (MM), which identifies the link between TLR and well-being, as well as four elements that are important for the success of luxury innovations: risk; trust; ethics and ambidextrous management practices. Further studies will be able to apply this conceptual model in diverse luxury markets to develop more industry-specific versions of it but should always maintain the model’s focus on individual and collective well-being to ensure that it supports the growth of transformative luxury in the future.Practical implicationsThe research has highlighted the benefits (individual and community well-being) of transformative research in the field of luxury products and services, but also the requirements (taking risk, trust and ambidextrous management) to achieve this transformative stage.Originality/valueThe study provides a guideline to be followed by the luxury yachting industry to reach its transformative potential.
Contributions of climate andBrassica oleraceacultivar to gastropod abundance and assemblage in southeastern Brazil
Authors: Farias Elizeu S. , D'ávila Sthefane , Santos Abraão A. , Santos Renata C. , Paes Jhersyka S. , Guedes Allana G. , Carvalho Geraldo A. , Picanço Marcelo C. 
Published: April 2023

AbstractTerrestrial gastropods (slugs and snails, Mollusca: Eupulmonata) are destructive pests of brassica crops. These organisms defoliate plants and contaminate the harvest, leading to reduced crop yield and marketability. Losses caused by molluscs have escalated in recent years in Brazil.We aimed to determine the seasonal activity of gastropods in brassica fields and unravel the environmental variables associated with these dynamics. Gastropod abundance, assemblage and within‐plant distribution were also compared amongBrassica oleraceacultivars (broccoli, cabbage and cauliflower).Mild temperatures and rainy periods were found to coincide with gastropod peaks. Regression analyses confirmed a positive association of rainfall and humidity with gastropod abundance, whereas gastropod abundance increased with decreasing temperature.Deroceras laeve(Müller) (Agriolimacidae) andBradybaena similaris(Férussac) (Bradybaenidae) were the most constant species. Mollusc abundance and assemblage differed amidB. oleraceacultivar; cabbage had the highest abundance and its species composition differed from broccoli and cauliflower. Slugs and snails were more concentrated on lower plant portions, regardless of the cultivar.Management efforts should be reinforced in mild‐temperature and rainy periods to reduce damage by gastropods, and cabbage should be monitored more closely than other cultivars.
Impact ofFKBP52on cell proliferation and hormone‐dependent cancers
Authors: Hanaki Shunsuke , Shimada Midori 
Published: April 2023

AbstractFK506 binding protein 52 (FKBP52) (gene nameFKBP4) is a 52 kDa protein that belongs to the FKBP family; it binds to the immunosuppressant FK506 and has proline isomerase activity. In addition to its FK domain‐containing peptidylprolyl isomerase activity, FKBP52 also acts as a cochaperone through the tetratricopeptide repeat domain that mediates binding to heat shock protein 90. Previous studies have reported that FKBP52 is associated with hormone‐dependent, stress‐related, and neurodegenerative diseases, revealing its diverse functions. In particular, the effects of FKBP52 on cancer have attracted considerable attention. FKBP52 promotes the growth of hormone‐dependent cancers by activating steroid hormone receptors. Recent studies have shown that the expression of FKBP52 is increased not only in steroid hormone‐dependent cancer cells but also in colorectal, lung, and liver cancers, revealing its diverse functions that contribute to cancer growth. This review summarizes reports related to hormone‐dependent cancer and cell proliferation in terms of the structure of FKBP52 and its function on interacting molecules.
A rapid review of children and young people's views of poverty and welfare in the context of Universal Credit
Authors: Bidmead Elaine , El Zerbi Catherine , Cheetham Mandy , Frost Sally 
Published: April 2023

AbstractChildren and young people's (CYP) life chances depend heavily on family resources. This paper reports a rapid review of qualitative/mixed method studies about Universal Credit undertaken with CYP in the UK; subsequently expanded to include additional descriptors of economic disadvantage. Sixteen studies were reviewed; narrative synthesis was used to explore themes. Most recruited CYP with experience of economic disadvantage; none explicitly reported perspectives of CYP experiencing disability or rurality. Findings show growing up in poverty has significant, negative impacts on health and well‐being, causing feelings of exclusion, shame and unfairness; raising important questions about the adequacy of welfare support in the UK.
Synthesis and application of nonionic Gemini surfactants based on grape seed oil
Authors: Si Kangwei , Xu Zhiwei , Zhou Xiangdong 
Published: April 2023

AbstractA series of vegetable oil‐based nonionic Gemini surfactant (GPNGS) was prepared using grape seed oil and polyethylene glycol monomethyl ether (350, 550, 750) as the primary raw materials. The chemical structures of different types of GPNGS were characterised by Fourier Transform–infrared spectroscopy, elemental analysis, proton nuclear magnetic resonance and carbon‐13 nuclear magnetic resonance. The critical micelle concentration (CMC) of GPNGS with different polyoxyethylene chain lengths was measured using the Wilhelmy ring method (CMC: ca. 1.4 × 10−4 to 5 × 10−4 mol/L). The results of wettability testing showed that the contact angle of GPNGS on polyamide film was ca. 46‐49°. In addition, the interaction of surfactants with acid dyes was also investigated. The ultraviolet spectrum showed a balance between dyes, surfactants and the dye/surfactant complex. Next, the GPNGS was used as a nylon 66 acid dye levelling agent. After adding 0.2 mmol/L of surfactants, the standard deviations (S(λ)) of nylon 66 dyeing decreased from 0.084 to ca. 0.036‐0.044, exhibiting a good levelling effect.
Uncommon spectral Doppler findings in patients with heart failure
Authors: Argulian Edgar , Agarwal Vikram 
Published: April 2023

AbstractSpectral Doppler examination is necessary for full hemodynamic assessment of patients with systolic heart failure. It is fully incorporated into comprehensive echocardiographic examination. In this manuscript, we describe two uncommon findings in patients with established severe left ventricular systolic dysfunction: notched aortic regurgitation and merged mitral regurgitation.
Higher body mass index after intrapartum antibiotic exposure in children persists over 10‐years
Authors: Sidell Margo A. , Getahun Darios , Tartof Sara Y. , Xiang Anny H. , Sharma Andrea J. , Mukhopadhyay Sagori , Puopolo Karen M. , Schrag Stephanie J. , Kunani Poornima , Koebnick Corinna 
Published: April 2023

SummaryExposure to intrapartum antibiotic prophylaxis to reduce perinatal group B streptococcal disease was associated with increased childhood body mass index (BMI) persisting to age 10 years compared to no exposure (Δ BMI at 10 years: vaginal delivery 0.14 kg/m2, caesarean 0.40 kg/m2).