bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANADOLU MASALLARINDAKİ YASAK (TABU) MOTİFLERİNİN KÜLTÜREL UNSURLAR AÇISINDAN İNCELENMESİ
Authors: BOZ İbrahim 
Published: March 2023

Bir milletin kültürel kodlarını içeren ve sözlü anlatılar olan masallarda oluştuğu yörenin dili, yaşayışı ve kültürel özelliklerine ait unsurları bulmak mümkündür. Bu bakımdan masallar kültürel belleğin gelecek kuşaklara aktarılmasında önemli işlevler üstlenir.
Masal motifleri ise birçok masalda tekrarlanan, genellikle sıra dışı, olağanüstü özellikler taşıyan ve oluştuğu kültürün özelliklerini barındıran küçük unsurlardır. Bu bakımdan motifler kurgunun oluşmasında, olayların ve kişilerin ortaya çıkmasında, kültürel kodların taşınmasında etkili olmaktadır. Ayrıca bu motifler arasında sıkı sıkıya bir ilişki vardır ve bir motif diğer motifin ortaya çıkmasında aracı rol üstlenir.
Bu çalışmada Motif Index’te bulunan yasak (tabu) motifi incelenmiştir. Öncelikle masal ve motif kavramları üzerinde durulmuştur. Daha sonra Pertev Naili Boratav’ın Zaman Zaman İçinde ve Az Gittik Uz Gittik kitapları incelenmiş ve bu kitaplarda yer alan, yasak motifleri içeren Bacı Bacı Can Bacı, Yedi Kardeşler, Dülger Kızı, Yıldırım Padişahı, Dünya Güzeli, Yeraltı Diyarının Kartalı adlı masallar incelenmeye çalışılmıştır. Bu anlatılarda yer alan yasak motiflerinin kültürel kodları taşıyıp taşımadığı ortaya çıkarılmaya çalışılmıştır. Ayrıca olayların gelişmesine ve kişilerin çeşitlenmesine olan etkisi üzerinde durulmuştur. Vladimir Propp’un Masalın Biçimbilimi adlı eserinde belirttiği üzere yasağın mutlaka çiğnendiği görülmüştür. Yasağın çiğnenmesinden sonra kahramanın başına birçok bela gelmekte, kahraman bu belaları aşmak için imtihan/imtihanlara tabi tutulmaktadır. Böylelikle yasak motifi diğer motiflerin ortaya çıkmasında ve anlatıya diğer olay/kişilerin katılmasında etkili olmaktadır. Bunun yanında Anadolu masallarında yer alan yasak motiflerinin kültürel kodları içerdiği ve bu kodları taşıyıcılık işlevinde kullanıldığı tespit edilmiştir.
Association between interleukin-2 (rs2069762) gene polymorphism and FVIII inhibitor development in Indonesian patients with severe hemophilia A
Authors: Marwanta Sri , Muhammad Faizal , Maryono Suradi , Salimah Kun , Sudarmadi Sihwidhi Dimas , Purwanto Bambang , Wasita Brian , Ardyanto Tonang Dwi , Soetrisno  
Published: March 2023

BACKGROUND Factor VIII (FVIII) inhibitors in hemophilia A (HA) patients render FVIII replacement therapy ineffective. Although its development cause is unclear, it has been classified into therapeutic and genetic-related etiologies. Single nucleotide polymorphisms (SNPs) in several cytokine genes, including interleukin (IL)-2, could increase the risk of FVIII inhibitor development. This study aimed to evaluate the association between IL-2 (rs2069762) gene SNP and FVIII inhibitor development in Indonesian patients with severe HA.
METHODS The IL-2 (rs2069762) gene SNP was examined in 119 HA patients. The presence of FVIII inhibitors was quantified using an enzyme-linked immunosorbent assay, with a titer of <0.28 ng/ml considered negative. Patients were divided into two groups: 59 with FVIII inhibitors (positive group) and 60 without inhibitors (negative group). The genotype of the subjects was determined using peripheral blood mononuclear cells and tetra-primer amplification refractory mutation system-polymerase chain reaction.
RESULTS There was no association between IL-2 (rs2069762) gene polymorphism and FVIII inhibitor development on genotypes (p = 0.138) and allele frequencies (p = 0.780).
CONCLUSIONS IL-2 (rs2069762) gene polymorphism is not a risk factor in the development of FVIII inhibitors in Indonesian patients with severe HA. Thus, further polymorphism studies in other cytokine genes are required to gain a comprehensive understanding of the FVIII inhibitor development.
Design of a switchable bifunctional terahertz metamaterial absorber from ultra-broadband to 10-band
Authors: Qi Yunping , Wang Li , Wen Yujiao , Chen Haowen , Yuan Yujiao , Zhou Zihao , Zhao Shiyu , Wang Xiangxian 
Published: March 2023

A bifunctional absorber with hybrid graphene–vanadium dioxide (VO2) is proposed and numerically investigated in the paper. Simulation results indicate that the absorber behaves as a broadband absorber with absorptance of more than 90% from 3.15 THz to 8.45 THz, when VO2 is in the metallic state. When VO2 is in the insulating state, the design exhibits a 10-band absorber, whose peak absorptances are above 90%. Broadband absorption is investigated by the impedance matching theory, and detailed physical studies indicate that it arises from electromagnetic resonance based on VO2 patches. Ten-band absorption originates from graphene plasmon (GP) resonance and Fabry–Perot cavity resonance. By adjusting the conductivity of VO2 and the Fermi level of graphene, the designed absorber not only can be independently tuned, but also has 91.9% modulation depth under broadband absorptance. Furthermore, the effect of incident angle on absorptance is investigated, and the absorber is polarization insensitive due to the symmetry of the structure. Benefiting from the above excellent performance, the bifunctional absorber offers great potential in terahertz applications, such as modulating, switching, and electromagnetic energy harvesting.
Theoretical analysis of self-phase-modulation-enabled spectral selection in hollow-core fibers: effect of ionization
Authors: Shi Zhuo , Chen Runzhi , Chang Guoqing 
Published: March 2023

We propose the generation of wavelength-tunable femtosecond pulses with µJ energy based on spectral broadening in hollow-core fibers (HCFs) filled with noble gas. A proper combination of gas type, gas pressure, and the HCF core radius ensures that the broadened spectrum consists of isolated spectral lobes; the selection of the outermost spectral lobes produces nearly transform-limited pulses. We performed a detailed numerical investigation of this method based on an antiresonant HCF with a 20 µm core radius filled with 17.3 bar Xe gas. By using 1.03 µm, 200 fs pulses with up to 20 µJ energy as the excitation pulse, this method can produce 100 fs pulses tuned from 0.74 to 1.25 µm with up to 5 µJ pulse energy. Further energy scaling is limited by the onset of ionization, which reduces the wavelength tuning range and causes a significant spectral blue shift. Increasing the input pulse energy beyond 45 µJ creates a strong spectral lobe peaking in the wavelength range of 0.92–0.95 µm with >10µJ energy. These results represent a two orders of magnitude improvement in the pulse energy compared to current tunable femtosecond sources based on nonlinear wavelength conversion in solid-core optical fibers.
Hybrid metasurface using graphene/graphitic carbon nitride heterojunctions for ultrasensitive terahertz biosensors with tunable energy band structure
Authors: Yao Haiyun , Sun Zhaoqing , Liang Lanju , Yan Xin , Wang Yaru , Yang Maosheng , Hu Xiaofei , Wang Ziqun , Li Zhenhua , Wang Meng , Huang Chuanxin , Yang Qili , Tian Zhongjun , Yao Jianquan 
Published: March 2023

Integrating novel materials is critical for the ultrasensitive, multi-dimensional detection of biomolecules in the terahertz (THz) range. Few studies on THz biosensors have used semiconductive active layers with tunable energy band structures. In this study, we demonstrate three THz biosensors for detecting casein molecules based on the hybridization of the metasurface with graphitic carbon nitride, graphene, and heterojunction. We achieved low-concentration detection of casein molecules with a 3.54 ng/mL limit and multi-dimensional sensing by observing three degrees of variations (frequency shift, transmission difference, and phase difference). The favorable effect of casein on the conductivity of the semiconductive active layer can be used to explain the internal sensing mechanism. The incorporation of protein molecules changes the carrier concentration on the surface of the semiconductor active layer via the electrostatic doping effect as the concentration of positively charged casein grows, which alters the energy band structure and the conductivity of the active layer. The measured results indicate that any casein concentration can be distinguished directly by observing variations in resonance frequency, transmission value, and phase difference. With the heterojunction, the biosensor showed the highest response to the protein among the three biosensors. The Silvaco Atlas package was used to simulate the three samples’ energy band structure and carrier transport to demonstrate the benefits of the heterojunction for the sensor. The simulation results validated our proposed theoretical mechanism model. Our proposed biosensors could provide a novel approach for THz metasurface-based ultrasensitive biosensing technologies.
Determinants of self-reported health status during COVID-19 lockdown among surveyed Ecuadorian population: A cross sectional study
Authors: Dueñas-Espín Iván , Jacques-Aviñó Constanza , Egas-Reyes Verónica , Larrea Sara , Torres-Castillo Ana Lucía , Trujillo Patricio , Peralta Andrés 
Published: March 2023

Objective
To examine the associations of sociodemographic, socioeconomic, and behavioral factors with depression, anxiety, and self-reported health status during the COVID-19 lockdown in Ecuador. We also assessed the differences in these associations between women and men.

Design, setting, and participants
We conducted a cross-sectional survey between July to October 2020 to adults who were living in Ecuador between March to October 2020. All data were collected through an online survey. We ran descriptive and bivariate analyses and fitted sex-stratified multivariate logistic regression models to assess the association between explanatory variables and self-reported health status.

Results
1801 women and 1123 men completed the survey. Their median (IQR) age was 34 (27–44) years, most participants had a university education (84%) and a full-time public or private job (63%); 16% of participants had poor health self-perception. Poor self-perceived health was associated with being female, having solely public healthcare system access, perceiving housing conditions as inadequate, living with cohabitants requiring care, perceiving difficulties in coping with work or managing household chores, COVID-19 infection, chronic disease, and depression symptoms were significantly and independently associated with poor self-reported health status. For women, self-employment, having solely public healthcare system access, perceiving housing conditions as inadequate, having cohabitants requiring care, having very high difficulties to cope with household chores, having COVID-19, and having a chronic disease increased the likelihood of having poor self-reported health status. For men, poor or inadequate housing, presence of any chronic disease, and depression increased the likelihood of having poor self-reported health status.

Conclusion
Being female, having solely public healthcare system access, perceiving housing conditions as inadequate, living with cohabitants requiring care, perceiving difficulties in coping with work or managing household chores, COVID-19 infection, chronic disease, and depression symptoms were significantly and independently associated with poor self-reported health status in Ecuadorian population.
Evolution of antibody titers after two doses of mRNA Pfizer-BioNTech vaccine and effect of the third dose in nursing home residents
Authors: Rodríguez-Avial Iciar , García-Salguero Cristina , Bermejo Laura , Teja Juan , Pérez-Cecilia Elisa , Delgado-Iribarren Alberto , Vigara Marta , Gil Pedro , Culebras Esther 
Published: March 2023

Objectives
We evaluated the IgG antibody titer against SARS-CoV-2 in 196 residents of a Spanish nursing home after the second dose of the BNT162b2 vaccine and the evolution of this titer over time. The role of the third dose of the vaccine on immune-response is also analysed in 115 of participants.

Methods
Vaccine response was evaluated 1, 3 and 6 months after second dose of Pfizer-BioNTech COVID-19 Vaccine and 30 days after booster vaccination. Total anti-RBD (receptor binding domain) IgG immunoglobulins were measured to assess response. Six month after the second dose of vaccine and previously to the booster, T-cell response was also measured in 24 resident with different antibody levels. T-spot Discovery SARS-CoV-2 kit was used to identify cellular immunogenicity.

Results
As high as 99% of residents demonstrated a positive serological response after second dose. Only two patients showed no serologic response, two men without records of previous SARS-CoV-2 infection. A higher immune response was associated with prior SARS-CoV-2 infection regardless of the gender or age. The anti-S IgG titers decreased significantly in almost all the participants (98.5%) after six months of vaccination whatever previous COVID-infection. The third dose of vaccine increased antibody titers in all patients, although initial vaccination values were not restored in the majority of cases.

Conclusion
The main conclusion of the study is that vaccine resulted in good immunogenicity in this vulnerable population. Nevertheless more data are needed on the long-term maintenance of antibody response after booster vaccination.
Cardiac magnetic resonance -detected myocardial injury is not associated with long-term symptoms in patients hospitalized due to COVID-19
Authors: Yar Aria , Uusitalo Valtteri , Vaara Satu M. , Holmström Miia , Vuorinen Aino-Maija , Heliö Tiina , Paakkanen Riitta , Kivistö Sari , Syväranta Suvi , Hästbacka Johanna 
Published: March 2023

Background
Long-term symptoms are frequent after coronavirus disease 2019 (COVID-19). We studied the prevalence of post-acute myocardial scar on cardiac magnetic resonance imaging (CMR) in patients hospitalized due to COVID-19 and its association with long-term symptoms.

Materials and methods
In this prospective observational single-center study, 95 formerly hospitalized COVID-19 patients underwent CMR imaging at the median of 9 months after acute COVID-19. In addition, 43 control subjects were imaged. Myocardial scar characteristic of myocardial infarction or myocarditis were noted from late gadolinium enhancement images (LGE). Patient symptoms were screened using a questionnaire. Data are presented as mean ± standard deviation or median (interquartile range).

Results
The presence of any LGE was higher in COVID-19 patients (66% vs. 37%, p<0.01) as was the presence of LGE suggestive of previous myocarditis (29% vs. 9%, p = 0.01). The prevalence of ischemic scar was comparable (8% vs. 2%, p = 0.13). Only two COVID-19 patients (7%) had myocarditis scar combined with left ventricular dysfunction (EF <50%). Myocardial edema was not detected in any participant. The need for intensive care unit (ICU) treatment during initial hospitalization was comparable in patients with and without myocarditis scar (47% vs. 67%, p = 0.44). Dyspnea, chest pain, and arrhythmias were prevalent in COVID-19 patients at follow-up (64%, 31%, and 41%, respectively) but not associated with myocarditis scar on CMR.

Conclusions
Myocardial scar suggestive of possible previous myocarditis was detected in almost one-third of hospital-treated COVID-19 patients. It was not associated with the need for ICU treatment, greater symptomatic burden, or ventricular dysfunction at 9 months follow-up. Thus, post-acute myocarditis scar on COVID-19 patients seems to be a subclinical imaging finding and does not commonly require further clinical evaluation.
Data linkage of two national databases: Lessons learned from linking the Dutch Arthroplasty Register with the Dutch Foundation for Pharmaceutical Statistics
Authors: van Brug Heather E. , Rosendaal Frits R. , van Steenbergen Liza N. , Nelissen Rob G. H. H. , Gademan Maaike G. J. 
Published: March 2023

Background
To provide guidance on data linkage in case of non-unique identifiers, we present a case study linking the Dutch Foundation for Pharmaceutical Statistics and Dutch Arthroplasty Register to investigate opioid prescriptions before/after arthroplasty.

Methods
Deterministic data linkage was used. Records were linked on: sex, birthyear, postcode, surgery date, or thromboprophylaxis initiation as a proxy for the surgery date. Different postcodes were used, depending on availability: patient postcode (available from 2013 onwards), hospital postcode with codes for physicians/hospitals, and hospital postcode with catchment area. Linkage was assessed in several groups: linked arthroplasties, linked on patient postcode, linked on patient postcode, and low-molecular-weight heparin(LWMH). Linkage quality was assessed by checking prescriptions after death, antibiotics after revision for infection, and presence of multiple prostheses. Representativeness was assessed by comparing the patient-postcode-LMWH group with the remaining arthroplasties. External validation was performed by comparing our opioid prescription rates with those derived from datasets from Statistics Netherlands.

Results
We linked 317,899 arthroplasties on patient postcode/hospital postcode(48%). Linkage on the hospital postcode appeared insufficient. Linkage uncertainty ranged from roughly 30% in all arthroplasties to 10–21% in the patient-postcode-LMWH-group. This subset resulted in 166.357(42%) linked arthroplasties after 2013 with somewhat younger age, fewer females, and more often osteoarthritis than other indications compared to the other arthroplasties. External validation showed similar increases in opioid prescription rates.

Conclusions
After identifier selection, checking data availability and internal validity, assessing representativeness, and externally validating our results we found sufficient linkage quality in the patient-postcode-LMWH-group, which consisted of around 42% of the arthroplasties performed after 2013.
Factors associated with children and young people’s mental health in the English-speaking Caribbean region: Systematic review and narrative synthesis
Authors: Liverpool Shaun , Draoui Yasmin , Tucker Judea , Pereira Brent , Prescod Jamal , Owen Michael , Trotman Catherine 
Published: March 2023

BackgroundStudies conducted in regions consisting of low and middle income and developing countries often report high prevalence of mental health problems among children and young people (CYP). To identify some of the contributing factors we examined the available evidence from research in one such setting.MethodsMultiple academic databases and grey literature sources were searched until January 2022. We then identified primary research focusing on CYP’s mental health in the English-speaking Caribbean region. Data was extracted and summarized to form a narrative synthesis of the factors associated with CYP’s mental health. The synthesis was then organised according to the social-ecological model. The Joanna Briggs Institute’s critical appraisal tools were used to examine the quality of the reviewed evidence. The study protocol was registered with PROSPERO, CRD42021283161.ResultsFrom 9684 records, 83 publications representing CYP ages 3 to 24 years from 13 countries met our inclusion criteria. The evidence was varied in quality, quantity and consistency for 21 factors associated with CYP’s mental health. Adverse events and negative peer to peer and sibling relationships were consistently associated with mental health problems, while helpful coping strategies were associated with better mental health. There were mixed findings for age, sex/gender, race/ethnicity, academic level, comorbidity, positive affect, health risks behaviours, religion/prayer, parent history, parent to parent and parent to child relationships, school/employment, geography and social status. There was also some limited evidence for associations between sexuality, screen time and policies/procedures and CYP’s mental health. At least 40% of the evidence contributing to each of the factors was judged as high quality.ConclusionIndividual, relationship, community and societal factors may influence CYP’s mental health outcomes in the English-speaking Caribbean. Knowledge of these factors is useful to inform early identification and early interventions. More research is needed to explore inconsistent findings and understudied areas.
Avaliação dos transtornos alimentares e seus impactos na qualidade de vida: Uma revisão sistemática da literatura
Authors: Aquino Mayco Carneiro , Braz Washington Moura , Oliveira Gislene Farias de 
Published: March 2023

Os transtornos alimentares são definidos como comportamentos físicos e alimentares inadequados e persistentes relacionados a emoções extremas que podem impactar diretamente na saúde física e psicossocial do indivíduo. Afetam mais de 30 milhões de pessoas e trazem consigo morbidade e mortalidade significativas. O rastreamento eficaz de transtornos alimentares é fundamental, pois esses transtornos são comumente subdiagnosticados e subtratados. O presente estudo objetivou uma revisão sistemática da literatura sobre a avaliação dos transtornos alimentares e seus impactos na qualidade de vida, nos últimos 10 anos, especificamente de 2010 a 2020, na base de dados PubMed, em artigos de língua portuguesa, inglesa ou espanola. Os resultados eliciaram 5 categorias: 1 - Implicações físicas/fisiológicas (3,3%); 2 – Implicações mentais/emocionais (43,3%); 3 – Implicações sociais (6,6%); 4 – Implicações na manutenção do tratamento (6,6%) e 5 – Implicações no agravamento, fatores predisponentes e reforço do transtorno alimentar (40%). Embora o número de artigos neste estudo seja relativamente pequeno ante as buscas iniciais na literatura, foram suficientes para retratar a realidade através de diversas dimensões possíveis, conforme as cinco categorias eliciadas. Mesmo que a amostra não permita uma generalização dos achados, mas proporcionaram uma concordância entre si quanto ao prejuízo dos Transtornos alimentares relativamente a qualidade de vida de seus portadores.
Influência da Propaganda na Automedicação entre a população de Vitória da Conquista
Authors: Azevedo Monarly Campos , Santos Rafael Pires dos , Menezes Ana Carolina Pessoa Moreira 
Published: March 2023

A automedicação é uma conduta praticada por boa parte da população, sendo definida como uso de medicamentos sem prescrição médica, no qual o indivíduo determina o fármaco e a dosagem que serão utilizados. Apesar de ser uma ação rotineira, pode apresentar riscos e agravos à saúde, como por exemplo mascarar sintomas de doenças, interações e intoxicações. Essa prática pode ser influenciada pelas propagandas medicamentosas, criadas pela indústria farmacêutica com o intuito de aumentar suas vendas. Neste contexto, o objetivo dessa pesquisa visou avaliar o perfil da prática de automedicação por habitantes de um município do sudoeste baiano e como o marketing influencia em seu comportamento de consumo. Foi realizada uma pesquisa de caráter transversal, de abordagem quantitativa no município de Vitória da Conquista – BA. A coleta foi realizada de forma presencial com 100 participantes durante o mês de outubro de 2022 por meio da aplicação de um questionário contendo 15 perguntas. Os resultados obtidos mostraram que 90% são adeptos a automedicação, sendo 75,5% destes devido à cefaleia. Apesar de 59,8% declararem que prescrição anterior é o principal motivo da automedicação, 42% já compraram medicamentos porque viram em propagandas e 54% acreditam que haja influência da propaganda sobre o consumo de fármacos. Com base nisso, percebeu-se que a prevalência da automedicação na amostra estudada é elevada, o que indica a necessidade de normas mais efetivas sobre marketing farmacêutico, visando a promoção do uso racional de medicamentos