bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clustering Technique Suitable for Eulerian Framework to Generate Multiple Scenarios from Ensemble Forecasts
Authors: Ono Kosuke 
Published: March 2023

Abstract
In operational weather forecasting, it is effective to aggregate information on all members of an ensemble forecast through cluster analysis. The temporal coherence of ensemble members in each cluster is an important piece of information about the robustness of the forecast scenario given by clusters. This information is especially important for forecasts for which the target area is a city or prefecture, that is, an Eulerian framework, because the members that compose each cluster can change over time because of the small size of the target area. This study provided the temporal coherence of members in clusters by performing principal component analysis and cluster analysis on 3-hourly 500-hPa geopotential height forecasts and linking the clustering results in the time direction. The new method provided a consistently well-divided forecast scenario throughout the forecast period for Eulerian frame forecasts, as well as information on the temporal coherency of the members in the clusters, which was demonstrated to be effective through the experiment to preselect a cluster with small errors. The application of the new technique to improve precipitation forecasts was also discussed.

Significance Statement
Numerical weather forecasts always contain errors. Although the uncertainty of such forecasts cannot be obtained from the forecast itself, ensemble forecasts, which are aggregates of many forecasts, can be used to estimate the uncertainty of the forecast. In this study, a new method was developed to transfer the information contained in many ensemble forecasts into four forecasts by cluster analysis and to provide forecast information suitable for a small forecasting area such as a prefecture. The use of this method for improving precipitation forecasts was also examined.
Aortic Injury From High-Speed Deceleration Against a Lap Belt in a 10-year-Old
Authors: Vines Katie , Ward Mark , Butts Charles , Capasso Thomas , Bright Andrew , Lee Yann-Leei , Polite Nathan , Kinnard Christopher , Simmons Jon , Maltese Carl , Williams Ashley , Mbaka Maryann 
Published: March 2023

Traumatic aortic injuries in children and adolescents are rare, and even more rare are blunt traumatic injury to the abdominal aorta in this population. Therefore, there are few reports discussing the presentation and repair of such injuries, especially within the pediatric population. We report the successful repair of traumatic abdominal aortic transection in a 10-year-old female after a high speed MVC. She arrived in extremis with a seatbelt sign and was taken emergently for damage control laparotomy with subsequent postoperative CT findings of aortic transection/dissection at L3 with active extravasation. She immediately underwent open thrombectomy of the bilateral iliac arteries, and repair of her aortic injury with a 12 × 7 mm Hemashield interposition graft extending just distal to the IMA and 1 cm proximal to the aortic bifurcation. There are little data regarding long-term outcomes of pediatric patients undergoing different aortic repair techniques, and further research is needed.
Distress During the COVID-19 Pandemic Among Local Public Health Workers in New York State
Authors: Lasher Emily G. , Seale Elizabeth , Fulkerson Gregory M. , Ravenhall Sarah , Thomas Alexander R. , Gadomski Anne M. 
Published: March 2023

Objective: Understanding the challenges public health workers have faced is critical to reinforcing, revitalizing, and strengthening the public health workforce. We measured and identified the level and causes of psychological distress among public health workers during the COVID-19 pandemic in New York State. Methods: We used a knowledge, attitudes, beliefs, and behaviors survey to ask public health workers at local health departments about their experiences working in public health during the pandemic, including questions relating to harassment from the public, workload, and work/life balance. We used the Kessler-6 scale to measure participants’ psychological distress using a 5-point Likert scale, with higher scores indicating greater psychological distress. We calculated descriptive statistics and conducted a regression analysis to determine the factors associated with public health worker psychological distress, and we coded open-ended comments for qualitative analysis. Results: During September 7-20, 2021, 231 public health workers from 38 local health departments completed the survey. Respondents were predominantly non-Hispanic White (89.6%), female (82.1%), full-time employees (95.1%), and located in Upstate New York. On a bivariate level, the strongest predictor of distress was job satisfaction (–0.388), followed closely by COVID-19 fatigue (0.386) and feeling bullied or harassed by the public (0.331). In the regression analysis, 2 additional factors were associated with distress: considering leaving their job due to the pandemic and concerns about exposure. Themes from the qualitative analysis strongly supported these findings. Conclusions: Understanding the challenges public health workers have faced during the pandemic is critical to inform the actions needed—stronger state laws protecting against harassment, workforce incentives, and commensurate funding—to reinforce and revitalize our frontline public health workforce.
Perceived Benefits and Barriers of a COVID-19 Test to Stay Program in a School District Serving Black or African American People With Low Income, December 2021
Authors: Kamitani Emiko , Holman Emily J. , Philpott David , Parasram Vidisha D. , Ruth Laird J. , Onyeuku Chisom , Carter Brittani , Gwynn Eugenia , Beck Timothy W. , Regan Kelly , Hagler LaVerne R. , Clark Angela , Shelley Gene , Thomas Ebony S. 
Published: March 2023

Objectives: Quarantine after exposure to COVID-19 has resulted in substantial loss of in-person learning in schools from prekindergarten through grade 12. Test to Stay (TTS), a strategy that limits the spread of SARS-CoV-2 while prioritizing in-person learning, requires substantial investment in resources. The objective of this study was to assess the perceived benefits, barriers, and facilitators of implementing TTS in an urban school district in the Midwest serving primarily Black or African American people with low income. Methods: In December 2021, we used a concurrent mixed-methods approach to understand perceived benefits, barriers, and facilitators of implementing TTS by combining quantitative analysis of telephone surveys conducted with parents (n = 124) and a qualitative inquiry involving key informants from the school district and local health department (n = 22). We analyzed quantitative data using descriptive statistics. We used thematic analysis to analyze qualitative data. Results: Quantitative findings showed that parents supported TTS because it was convenient (n = 83, 97%) and effective (n = 82, 95%) in keeping students learning in person (n = 82, 95%) and preventing the spread of COVID-19 (n = 80, 93%). Qualitative interviews with informants found that having a clear protocol and assigning staff to specified tasks allowed for successful TTS implementation. However, insufficient staffing and testing resources, parent mistrust of testing, and lack of communication from schools were perceived barriers. Conclusion: The school community strongly supported TTS despite the many implementation challenges faced. This study emphasized the importance of ensuring resources for equitable implementation of COVID-19 prevention strategies and the critical role of communication.
STEM sense of belonging for 12-13 year-old talent search participants: Does gender matter?
Authors: Meadows Monica C. , Robinson Ann 
Published: March 2023

Gaps in STEM performance have narrowed over the last 50 years (Leaper et al., 2012; National Science Foundation, 2013). Nonetheless, disparities remain in many STEM fields – with the largest occurring in the physical sciences, computer science, and engineering (UNESCO., 2012). Although gender gaps in science and math performance have been closing, gaps in STEM self-concept and aspirations continue. We investigated academically advanced 12–13 year-old students’ sense of belonging to STEM disciplines and examined the relationship among STEM sense of belonging, STEM classroom/peer climate, amount of STEM exposure, and the strength of self-identification with STEM. Although previous research established that features of the STEM classroom/peer climate can promote as well as detract from underrepresented students’ interest and retention in STEM (Riegle-Crumb et al., 2006; Roberts et al., 2018; Stake & Nickens, 2005), less is known about constructs that underlie STEM sense of belonging. Our results indicated no significant difference in STEM sense of belonging between academically advanced females and males. However, there is a statistically significant interaction between gender and self-identification with STEM. Key predictors of STEM sense of belonging identified by our regression model include classroom/peer climate and STEM self-identification.
Temporal profile of intranasal oxytocin in the human autonomic nervous system at rest: An electrocardiography and pupillometry study
Authors: Cosme Gonçalo , Arriaga Patrícia , Rosa Pedro J. , Mehta Mitul A. , Prata Diana 
Published: March 2023

Background: Human social behavior is modulated by oxytocin (OT). Intranasal administration of OT (IN-OT) is a noninvasive route shown to elicit changes in the autonomic nervous system (ANS) activity; however, IN-OT’s effect on the temporal profile of ANS activity at rest is yet to be described. Aims: We aimed to describe the temporal profile of IN-OT at six 10-min time windows from 15- to 100-min post-administration in 20 male participants at rest while continuously recording their pupillary in an eyes-open condition and cardiac activity in eyes-open and eyes-closed conditions. Methods: We used a double-blind, placebo-controlled, within-subjects design study where we extracted two proxies of parasympathetic nervous system (PNS) activity: high-frequency heart rate variability (HF-HRV) and pupillary unrest index (PUI); and a proxy of sympathetic nervous system activity: sample entropy of the pupillary unrest. Results: In the eyes-open condition, we found an effect of IN-OT on the proxies of PNS activity: decreased PUI in the three-time windows post-administration spanning 65–100 min, and as an exploratory finding, an increased HF-HRV in the 80–85 min time window. Conclusions: We suggest there is a role of OT in PNS regulation that may be consistent with OT’s currently theorized role in the facilitation of alertness and approach behavior.
A retrospective matched case–control comparison of non-fatal hanging to non-fatal self-poisoning in a sample of Australian men and women
Authors: Ghani Ayaz , Talbot Daniel , Ma Cassandra , Harris Anthony 
Published: March 2023

Objective Our study examined the characteristics of individuals who survived attempted hanging and compared this group to a randomly selected comparison group of patients with non-fatal self-poisoning. Method Non-fatal hanging cases were identified from case files from an Australian public hospital. They were matched by age, sex, and month of presentation with double the number of non-fatal self-poisoning cases. Patients were compared on demographic and clinical characteristics, as well as length of stay in hospital and discharge plan. Results Most non-fatal hanging patients were males with medium suicidal intent, and a significant proportion misused alcohol. In this group, women were more likely than men to have past psychiatric care, and men were more likely to misuse alcohol and stimulants. In comparison to the self-poisoning group, the non-fatal hanging group had higher suicidal intent but proportionally lower history of self-harm and psychiatric care, or benzodiazepine misuse. Conclusion People who self-harm by hanging have higher suicidal intent, misuse alcohol more often, and are less likely to be in psychiatric care. They may benefit from a general community intervention, rather than one based upon interventions with people already in psychiatric care.
Less groin pain with dual-mobility bearings versus fixed bearings in total hip arthroplasty
Authors: Dubin Jeremy A , Westrich Geoffrey H 
Published: March 2023

Introduction: The relationship between implant type, dual mobility (DM) or fixed bearing (FB), and postoperative groin pain remains unexplored. We examined the incidence of groin pain in DM implants and compare this to a cohort of FB THA patients. Methods: From 2006 to 2018, a single surgeon performed 875 DM THA and 856 FB THA procedures with 2.8-year and 3.1-year follow-up, respectively. Each patient received a questionnaire postoperatively and was asked if they had any groin pain (yes/no). Secondary measurements were implant characteristics such as head size, head offset, cup size, and cup-to-head ratio. Additional PROMs that were collected included: Veterans RAND 12 (VR-12), University of California Los Angeles (UCLA) activity score, Pain visual analogue scale (Pain VAS), and range of motion (ROM). Results: The incidence of groin pain was 2.3% in the DM THA cohort and 6.3% in the FB THA group ( p  < 0.001). Also, low head offset (⩽0 mm) had a significant odds ratio (1.61) for groin pain in both cohorts. There was no significant difference in terms of revision rate between the cohorts (2.5% vs. 3.3%, p = 0.39) at the latest follow up. Conclusions: This study demonstrated a lower incidence of groin pain (2.3%) in patients with a DM bearing compared to a FB (6.3%) and a greater risk of groin pain with low head offset (<0 mm). As such, surgeons should try to recreate offset of the hip compared to the contralateral side to avoid groin pain.
Longitudinal Transition Patterns of Tobacco Use Among Youth and Young Adults Never Tobacco Product Users: Findings From the Population Assessment of Tobacco and Health Study, 2014-2019
Authors: Bluestein Meagan A. , Kuk Arnold E. , Harrell Melissa B. , Chen Baojiang , Hébert Emily T. , Pérez Adriana 
Published: March 2023

Aims To identify, visualize, and describe the prevalence of within-product patterns of tobacco use behaviors for e-cigarettes, cigarettes, and hookah (TP) by 3 age groups (ie, 12-14-year-old, 15-17-year-old, and 18-20-year-old) with U.S. nationally representative data. Methods In 2014-2015, never users of each (TP) and age group were followed-up longitudinally between 2015-2019 using five transition states: non-susceptible to (TP) use, susceptible to (TP) use, ever (TP) use, past 30-day (TP) use, and discontinued past 30-day (TP) use. Sankey diagrams were used to graphically visualize patterns in tobacco use behaviors across time. Results Among 12-14-year-old who were never users and susceptible to each TP from 2014-2017, 7% initiated ever e-cigarette use and 9.4% first reported past 30-day use by 2018-2019; 5.8% initiated ever cigarette use and 3% first reported past 30-day cigarette use by 2018-2019; and, 4.5% initiated ever hookah use and 1.0% first reported past 30-day hookah use by 2018-2019. Among 15-17-year-old who were never users and susceptible to each TP from 2014-2017, 4.2% initiated ever e-cigarette use and 9.0% first reported past 30-day use by 2018-2019; 4.5% initiated ever cigarette use and 3% first reported past 30-day cigarette use by 2018-2019; and, 4.5% initiated ever hookah use and 2.4% first reported past 30-day hookah use by 2018-2019. Among 18-20-year-old who were never users and susceptible to each TP from 2014-2017, 3.2% initiated ever e-cigarette use and 3.6% first reported past 30-day e-cigarette use by 2018-2019; 3.0% initiated ever cigarette use and 2.3% first reported past 30-day cigarette use; and, 2.8% initiated ever hookah use and 1.0% first reported past 30-day hookah use by 2018-2019. Conclusions From 2014 to 2019, onset and progression of e-cigarette, cigarette, and hookah use occurred more frequently in 12-14 and 15-17-year-old than in young adults 18-20-year-old.
How Long Should We Keep Children’s Surgical Sites Dry? The Incidence of Infection and Dehiscence After Pediatric Office Procedures
Authors: Palacios Jose F. , Hazkour Nissim , Robinson Emma , Walsh Landis R. , Bastidas Nicholas 
Published: March 2023

Objective: Studies evaluating the relationship between bathing and adverse surgical site events are sparse. In this study, we examine the incidence of surgical site infection (SSI) and dehiscence in a cohort of pediatric patients who were allowed to bathe 24 hours after their office procedures. Methods: Pediatric patients who underwent office procedures by a single plastic surgeon from 2017 to 2021 were included. All patients were allowed to bathe 24 hours after their office-based skin procedure. Age, sex, procedure type, pre procedure diagnosis, relevant past medical history, instances of dehiscence, and SSI were recorded. Results: 738 pediatric patients were included. Median age was 3.3 years(range 2 months-7 years), 46% were male and 54% were female. The most common pre procedure diagnoses were branchial vestige (24%), melanocytic nevi (21%), polydactyly (15%), congenital non-neoplastic nevus (11%), cyst (9%), hypertrophic scar (8%), and hemangioma(5%). No patients received systemic antibiotics post-procedurally. Six instances of dehiscence were recorded, and no SSIs were seen in any of the 738 patients. Conclusions: The low dehiscence rate and lack of SSIs in our cohort supports the hypothesis that children can bathe normally 24 hours after office procedures without adverse consequences. This recommendation can reduce the burden of post procedure wound care by reducing the length of time patients have to modify their bathing routines.
Development and validation of a coagulation-related genes prognostic model for hepatocellular carcinoma
Authors: Yang Wan-Xia , Gao Hong-Wei , Cui Jia-Bo , Zhang An-An , Wang Fang-Fang , Xie Jian-Qin , Lu Ming-Hua , You Chong-Ge 
Published: March 2023

Abstract
Background
Hepatocellular carcinoma (HCC) has a high incidence and mortality worldwide, which seriously threatens people's physical and mental health. Coagulation is closely related to the occurrence and development of HCC. Whether coagulation-related genes (CRGs) can be used as prognostic markers for HCC remains to be investigated.

Methods

Firstly, we identified differentially expressed coagulation-related genes of HCC and control samples in the datasets GSE54236, GSE102079, TCGA-LIHC, and Genecards database. Then, univariate Cox regression analysis, LASSO regression analysis, and multivariate Cox regression analysis were used to determine the key CRGs and establish the coagulation-related risk score (CRRS) prognostic model in the TCGA-LIHC dataset. The predictive capability of the CRRS model was evaluated by Kaplan–Meier survival analysis and ROC analysis. External validation was performed in the ICGC-LIRI-JP dataset. Besides, combining risk score and age, gender, grade, and stage, a nomogram was constructed to quantify the survival probability. We further analyzed the correlation between risk score and functional enrichment, pathway, and tumor immune microenvironment.

Results
We identified 5 key CRGs (FLVCR1, CENPE, LCAT, CYP2C9, and NQO1) and constructed the CRRS prognostic model. The overall survival (OS) of the high-risk group was shorter than that of the low-risk group. The AUC values for 1 -, 3 -, and 5-year OS in the TCGA dataset were 0.769, 0.691, and 0.674, respectively. The Cox analysis showed that CRRS was an independent prognostic factor for HCC. A nomogram established with risk score, age, gender, grade, and stage, has a better prognostic value for HCC patients. In the high-risk group, CD4+T cells memory resting, NK cells activated, and B cells naive were significantly lower. The expression levels of immune checkpoint genes in the high-risk group were generally higher than that in the low-risk group.

Conclusions
The CRRS model has reliable predictive value for the prognosis of HCC patients.
Potential utility of a multi-component coagulation factor panel to calculate MELD scores and assess the risk of portal vein thrombosis in chronic liver disease
Authors: Lewis Clayton S. , Bari Khurram , Xie Changchun , Sherman Kenneth E. , Vasse Marc , Van Dreden Patrick , Bogdanov Vladimir Y. 
Published: March 2023

Abstract
Background
Current quantitative approaches to assess chronic liver disease (CLD) severity have limitations. Further, portal vein thrombosis (PVT) pre-liver transplant (LT) is a major contributor to morbidity in CLD; the means of detecting and/or predicting PVT are limited. We sought to explore whether plasma coagulation factor activity levels can serve as a substitute for prothrombin time/international normalized ratio (PT/INR) in the Model for End-stage Liver Disease (MELD), and/or help assess the risk of PVT.

Methods
Plasma activity levels of Factor V (FV), Factor VIII (FVIII), Protein C (PC), and Protein S (PS) and the concentrations of D-dimer, sP-selectin, and asTF were assessed in two cohorts of CLD patients (ambulatory, n = 42; LT, n = 43).

Results
FV and PC activity levels strongly correlated with MELD scores, which enabled the development of a novel scoring system based on multiple linear regressions of the correlations of FV and PC activity with MELD-Na that substitutes PT/INR. Six-month and 1-year follow-up revealed that our novel approach was non-inferior to MELD-Na at predicting mortality. A significant inverse correlation between FVIII activity levels and PVT was found in the LT cohort (p = 0.010); FV and PS activity levels were in-trend (p = 0.069, p = 0.064). We developed a logistic regression-based compensation score to identify patients at risk of PVT.

Conclusions
We demonstrate that FV and PC activity levels may be used to replace PT/INR in MELD scoring. We also show the potential of using the combination of FV, FVIII, and PS activity levels to assess the risk of PVT in CLD.