bluuebunny/crossref_metadata_2025_split huggingface dataset:
Russophobia and Ways to Neutralize It in the Media
Authors: Slyshkin Gennadiy , Malygina L. , Sorokin A. , Belasheva H. 
Published: May 2023

As part of the research of modern media discourse, a round table “Russophobia and ways to neutralize it in the mass media” was held at the research laboratory “Linguistic Security and Psychology of Information Impact” of the Institute of Law and National Security of the Russian Academy of National Economy and Public Administration under the President of the Russian Federation. Laboratory specialists and invited experts discussed the problem of Russophobia as part of the current media discourse in the mass media, as well as in new media (social networks, blogosphere, messengers, network video hosting channels, etc.), as well as, in general, destructive information flows aimed at destroying the cultural and social integrity of the Russian Federation (“cancel Russian culture”). The emphasis
in the discussion of the laboratory experts is on the relevance of training specialists in working with media communication tools. During the discussion, such concepts as “linguistic security”, “Russophobia” and their impact on the media culture of Russian society were analyzed. As a result of the round table, measures were proposed to enhance linguistic security, train journalists and specialists in working with mass media, prepared
to analyze destructive information flows using the entire arsenal of linguistic expertise in countering Russophobia.
CONFLICT MANIFESTATIONS OF VIOLATIONS OF PRIVACY AND PUBLICITY IN EVERYDAY DISCOURSE
Authors: Dubrovchenko Elena 
Published: May 2023

Introduction. The relevance of the study is determined by the importance of communicative distance in communication and the necessity to study the types of violation of communicative distance, as well as verbal and non-verbal means which describe them.
Aim. The aim of the article is to establish the violations of the communicative distance in everyday discourse and to conduct the analysis of these violations.
Methodology and research methods. Main research methods include the hypothetical-deductive method, the interpretive method, the contextual analysis and introspection.
Results. In the theoretical part the concepts of everyday discourse and communicative distance are considered, the components of a typical situation of privacy violation are indicated, the classifications of violations of communicative distance proposed by scientists are given. In the practical part, based on the proposed classifications and the results of the study, the author’s classification of violations of the correlation between privacy and publicity in everyday discourse is worked out. It has been established that these violations are multi-vector. Violations directed towards reducing the communicative distance are presented more widely than violations directed towards its increasing. A person who breaks the distance can play both an active role in a communicative situation and a passive one. Violations can be intentional and unintentional. As a result of the analysis, ways of expressing violations of the correlation between privacy and publicity in communication, as well as verbal and non-verbal means of indicating the revealed violations, were identified.
Scientific novelty lies in working out the author’s classification of violations of the correlation between privacy and publicity in everyday discourse.
Practical significance. The results can be used by specialists who are interested in the problems of communicative distance.
Media Image of Russia Metaphorization (Based on the English Language)
Authors: Greydina N. 
Published: May 2023

The presented research article reflects the contextual content-semantic analysis of the concept of “media image of Russia” in media information field. Along with this, the method of media analysis of the text from the political and socio-cultural positions is implemented. The image of Russia is considered within the framework of media discourse through the use of metaphorization process. The designation is given to the manipulative essence
of the US mass media. The concepts of “image of the country” and “media image of the country” are differentiated in the media plane context on the material of the US mass media texts. Various forms and means of creating a negative image of Russia within the media information field are established. The conducted research makes it possible to clarify the concept of stereotypical media information. The theoretical positions of the research actualize the analysis of the cognitive format of the media image of Russia in the US media, from today’s perspective. Both headline and text media materials are subject to research. The resulting database is represented by a wide range of thematic examples taken from media analysis of original articles of political nature.
role of the gut microbiota in pathogenesis and treatment of depression
Authors: Bogusz Klaudia , Baran Natalia , Maksymowicz Marcela , Bielak Adriana , Nowak Aleksandra , Cywka Łucja , Szwed Weronika , Nowak Alicja , Machowiec Piotr 
Published: May 2023

Introduction and purpose
Depression is the most common mental disorder, but the exact mechanisms underlying the pathophysiology of depression remain unknown. Abundant research evidence suggests that changes in the gut microbiota play a key role in the pathophysiology of depression through the brain-gut-microbiota axis. The aim of this study was to present the current state of knowledge on the role of gut microbiota in pathogenesis and treatment of depression and discuss its potential as a therapeutic target for depression
A brief description of the state of knowledge
The digestive tract and the processes which are set in it as well as the inhabitting microorganisms have a significant impact on our mental health and mood. The scientific research repeatidly confirm a strict relationship between the digestive and nervous systems. A microbiome-based approach is becoming increasingly prevalent in the understanding and treatment of neuropsychiatric disorders, especially depression. Antidepressants which are today the first-line therapy in the treatment of this disease are based inter alia on the antimicrobial and immunomodulatory mechanism of action.
Conclusion
Immune cells which are settled in the intestines affect not only our physical health but also the mental one. Due to the relationship between depression and the gut microbiota, we have many treatment options that involve direct modification of the composition of the microbiome which include prebiotics, probiotics (psychobiotics) and faecal microbiome transplantation.
Product Recalls and Supply Base Innovation
Authors: Zou Fan , Dong Yan , Song Sining , Rungtusanatham Manus 
Published: May 2023

Problem definition: Suppliers are increasingly involved in innovation activities that contribute to a firm’s product quality and introduce risks to firms’ quality control, leading to quality failures and recalls. This quality trade-off suggests the possibility of a nonlinear relationship between supplier innovation and product recalls, which is the focus of this research. Recall literature focuses on firms’ internal drivers of recalls, whereas anecdotal evidence increasingly points to the role of external drivers, such as suppliers. We contribute to the literature by examining supplier innovation as an external driver leading to recalls via quality and risk spillovers. Methodology/results: We collect and assemble a unique panel data set of consumer product recalls from firms and their supply bases (i.e., first tier suppliers). We estimate econometric models to examine the nonlinear relationship between supply base innovation, measured by research and development (R&D) intensity of the supply bases, and the likelihood of product recalls. We find a quadratic (i.e., U-shaped) relationship between the probability of recalls and supply base R&D intensity. We also find that this nonlinear relationship is critically related to three specific sources of risk: radicalness of supplier innovation, technological distance between firms and their suppliers, and complexity of supply base. Managerial implications: Our findings suggest that firms should be mindful of the quality trade-offs in encouraging supplier innovation to reduce product recalls. Further, to minimize recall risks, firms should better evaluate and manage the risks associated with external supplier knowledge that is novel and different and closely work with global suppliers to reduce coordination challenges in knowledge transfer and integration. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.1213 .
SARS-CoV-2 transmission with and without mask wearing or air cleaners in schools in Switzerland: A modeling study of epidemiological, environmental, and molecular data
Authors: Banholzer Nicolas , Zürcher Kathrin , Jent Philipp , Bittel Pascal , Furrer Lavinia , Egger Matthias , Hascher Tina , Fenner Lukas 
Published: May 2023

Background
Growing evidence suggests an important contribution of airborne transmission to the overall spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), in particular via smaller particles called aerosols. However, the contribution of school children to SARS-CoV-2 transmission remains uncertain. The aim of this study was to assess transmission of airborne respiratory infections and the association with infection control measures in schools using a multiple-measurement approach.

Methods and findings
We collected epidemiological (cases of Coronavirus Disease 2019 (COVID-19)), environmental (CO2, aerosol and particle concentrations), and molecular data (bioaerosol and saliva samples) over 7 weeks from January to March 2022 (Omicron wave) in 2 secondary schools (n = 90, average 18 students/classroom) in Switzerland. We analyzed changes in environmental and molecular characteristics between different study conditions (no intervention, mask wearing, air cleaners). Analyses of environmental changes were adjusted for different ventilation, the number of students in class, school and weekday effects. We modeled disease transmission using a semi-mechanistic Bayesian hierarchical model, adjusting for absent students and community transmission.
Molecular analysis of saliva (21/262 positive) and airborne samples (10/130) detected SARS-CoV-2 throughout the study (weekly average viral concentration 0.6 copies/L) and occasionally other respiratory viruses. Overall daily average CO2 levels were 1,064 ± 232 ppm (± standard deviation). Daily average aerosol number concentrations without interventions were 177 ± 109 1/cm3 and decreased by 69% (95% CrI 42% to 86%) with mask mandates and 39% (95% CrI 4% to 69%) with air cleaners. Compared to no intervention, the transmission risk was lower with mask mandates (adjusted odds ratio 0.19, 95% CrI 0.09 to 0.38) and comparable with air cleaners (1.00, 95% CrI 0.15 to 6.51).
Study limitations include possible confounding by period as the number of susceptible students declined over time. Furthermore, airborne detection of pathogens document exposure but not necessarily transmission.

Conclusions
Molecular detection of airborne and human SARS-CoV-2 indicated sustained transmission in schools. Mask mandates were associated with greater reductions in aerosol concentrations than air cleaners and with lower transmission. Our multiple-measurement approach could be used to continuously monitor transmission risk of respiratory infections and the effectiveness of infection control measures in schools and other congregate settings.
Barriers and facilitators to anti-retroviral therapy adherence among adolescents aged 10 to 19 years living with HIV in sub-Saharan Africa: A mixed-methods systematic review and meta-analysis
Authors: Hlophe Londiwe D. , Tamuzi Jacques L. , Shumba Constance S. , Nyasulu Peter S. 
Published: May 2023

BackgroundHuman Immunodeficiency Virus (HIV) significantly affects adolescents globally, with the sub-Saharan Africa (SSA) reporting a high burden of the disease. HIV testing, treatment, and retention to care are low among adolescents. We conducted a mixed-method systematic review to assess anti-retroviral therapy (ART) adherence; barriers and facilitators to ART adherence and ART outcomes among adolescents living with HIV and on ART in sub-Saharan Africa.MethodsWe conducted searches in four scientific databases for studies conducted between 2010 and March 2022 to identify relevant primary studies. Studies were screened against inclusion criteria and assessed for quality, and data was extracted. Meta-analysis of rates and odd ratios was used to plot the quantitative studies and meta-synthesis summarized the evidence from qualitative studies.ResultsA total of 10 431 studies were identified and screened against the inclusion/ exclusion criteria. Sixty-six studies met the inclusion criteria (41 quantitative, 16 qualitative, and 9 mixed-methods study designs). Fifty-three thousand two hundred and seventeen (53 217) adolescents (52 319 in quantitative studies and 899 in qualitative studies) were included in the review. Thirteen support focused interventions for improved ART adherence were identified from quantitative studies. The plotted results from the meta-analysis found an ART adherence rate of 65% (95%CI 56–74), viral load suppression was 55% (95%CI 46–64), un-suppressed viral load rate of 41% (95%CI 32–50), and loss to follow up of 17% (95%CI 10–24) among adolescents. Meta-synthesis found six themes of barriers to ART (social, patient-based, economic, health system-based, therapy-based, and cultural barriers) in both the qualitative and quantitative studies, and three themes of facilitators to ART were also identified (social support, counselling, and ART education and secrecy or confidentiality) from qualitative studies.ConclusionART adherence remains low among adolescents in SSA despite multiple interventions implemented to improve ART adherence. The low adherence rate may hinder the attainment of the UNAIDS 2030 targets. Additionally, various barriers to ART adherence due to lack of support have been reported among this age group. However, interventions aimed at improving social support, educating, and counselling adolescents may improve and sustain ART adherence.Trial registrationSystematic review registration:PROSPEROCRD42021284891.
Epidemiology, clinical features, and surgical outcomes of acute acquired concomitant esotropia associated with myopia
Authors: Roda Matilde , di Geronimo Natalie , Valsecchi Nicola , Gardini Lorenzo , Fresina Michela , Vagge Aldo , Fontana Luigi , Schiavi Costantino 
Published: May 2023

Purpose
To analyze epidemiology, clinical features, and surgical outcomes of type III acute acquired concomitant esotropia (Bielschowsky esotropia (BE)).

Methods
The medical charts of patients diagnosed with acquired concomitant esotropia between 2013 and 2021 were reviewed. Assessed data were age, gender, age at diplopia onset, age at the diagnosis, refraction, visual acuity, neuroimaging, diplopia onset, angle of deviation, stereopsis, surgical procedure, amount of surgery, and relapse of diplopia after surgery. Moreover, we investigated the correlation between the use of electronic devices and the onset of diplopia.

Results
One hundred seventeen patients (mean age 35.07 ± 15.81 years) were included in the study. The mean delay to the diagnosis was 3.29 ± 3.62 years. Myopia range was 0 to 17 diopters spherical equivalent. 66,3% spent more than 4 hours a day using laptops, tablets, or smartphones at the onset of diplopia, and 90,6% presented a subacute onset. None showed neurologic signs or symptoms. Patients who underwent surgery were ninety-three, with a rate of surgical success of 93.6%, and a relapse rate of 17.2%. A negative correlation resulted between pre-operative deviation and age at diagnosis (ρ = -0.261; p<0.05), whereas factors associated with surgical failure were older age at diplopia onset (p = 0.042) and longer delay between onset and diagnosis (p = 0.002).

Conclusion
We registered an outstanding increase in prevalence of BE, which could be related to the exponential increase in the use of electronic devices for professional, educational, and recreational purposes. A prompt diagnosis and an augmented dose of surgery allows good motor and sensory results.
DDX43 mRNA expression and protein levels in relation to clinicopathological profile of breast cancer
Authors: Amer Noha N. , Khairat Rabab , Hammad Amal M. , Kamel Mahmoud M. 
Published: May 2023

Background
Breast cancer (BC) is the most often diagnosed cancer in women globally. Cancer cells appear to rely heavily on RNA helicases. DDX43 is one of DEAD- box RNA helicase family members. But, the relationship between clinicopathological, prognostic significance in different BC subtypes and DDX43 expression remains unclear. Therefore, the purpose of this study was to assess the clinicopathological significance of DDX43 protein and mRNA expression in different BC subtypes.

Materials and methods
A total of 80 females newly diagnosed with BC and 20 control females that were age-matched were recruited for this study. DDX43 protein levels were measured by ELISA technique. We used a real-time polymerase chain reaction quantification (real-time PCR) to measure the levels of DDX43 mRNA expression. Levels of DDX43 protein and mRNA expression within BC patients had been compared to those of control subjects and correlated with clinicopathological data.

Results
The mean normalized serum levels of DDX43 protein were slightly higher in control than in both benign and malignant groups, but this result was non-significant. The mean normalized level of DDX43 mRNA expression was higher in the control than in both benign and malignant cases, although the results were not statistically significant and marginally significant, respectively. Moreover, the mean normalized level of DDX43 mRNA expression was significantly higher in benign than in malignant cases. In malignant cases, low DDX43 protein expression was linked to higher nuclear grade and invasive duct carcinoma (IDC), whereas high mRNA expression was linked to the aggressive types of breast cancer such as TNBC, higher tumor and nuclear grades.

Conclusion
This study explored the potential of using blood DDX43 mRNA expression or protein levels, or both in clinical settings as a marker of disease progression in human breast cancer. DDX43 mRNA expression proposes a less invasive method for discriminating benign from malignant BC.
The impact of injury of the chorda tympani nerve during primary stapes surgery or cochlear implantation on taste function, quality of life and food preferences: A study protocol for a double-blind prospective prognostic association study
Authors: Blijleven Esther E. , Wegner Inge , Stokroos Robert J. , Thomeer Hans G. X. M. 
Published: May 2023

Background
The chorda tympani nerve (CTN) is a mixed nerve, which carries sensory and parasympathetic fibres. The sensory component supplies the taste sensation of the anterior two-thirds of the ipsilateral side of the tongue. During middle ear surgery the CTN is exposed and frequently stretched or sacrificed, because it lacks a bony covering as it passes through the middle ear. Injury may cause hypogeusia, ageusia or altered taste sensation of the ipsilateral side of the tongue. To date, there is no consensus regarding which type of CTN injury (sacrificing or stretching), during middle ear surgery, leads to the least burden for the patient.

Methods
A double-blind prospective prognostic association study was designed in a single medical centre in the Netherlands to determine the effect of CTN injury on postoperative taste disturbance and quality of life. 154 patients, who will undergo primary stapes surgery or cochlear implantation will be included. The taste sensation, food preferences and quality of life of these patients will be evaluated preoperatively and at one week, six weeks and six months postoperatively using the Taste Strip Test, Electrogustometry, supplementary questionnaire on taste disturbance, Macronutrient and Taste Preference Ranking Task, Appetite, Hunger and Sensory Perception questionnaire and Questionnaire of Olfactory Disorders to assess the association of these outcomes with CTN injury. Evaluation of olfactory function will only take place preoperatively and at one week postoperatively using the Sniffin’ Sticks. The patient and outcome assessor are blinded to the presence or absence of CTN injury.

Discussion
This study is the first to validate and quantify the effect of chorda tympani nerve injury on taste function. The findings of this study may lead to evidence-based proof of the effect of chorda tympani injury on taste function with consequences for surgical strategies.

Trial registration
Netherlands Trial Register NL9791. Registered on 10 October 2021.
Gastric microbiome changes in relation with Helicobacter pylori resistance
Authors: Dewayani Astri , Afrida Fauzia Kartika , Alfaray Ricky Indra , Waskito Langgeng Agung , Doohan Dalla , Rejeki Purwo Sri , Alshawsh Mohammed Abdullah , Rezkitha Yudith Annisa Ayu , Yamaoka Yoshio , Miftahussurur Muhammad 
Published: May 2023

Introduction
Inadequate antimicrobial treatment has led to multidrug-resistant (MDR) bacteria, including Helicobacter pylori (H. pylori), which one of the notable pathogens in the stomach. Antibiotic-induced changes in the microbiota can negatively affect the host. This study aimed to determine the influence of H. pylori resistance on the diversity and abundance of the stomach microbiome.

Methods
Bacterial DNA was extracted from biopsy samples of patients presenting dyspepsia symptoms with H. pylori positive from cultures and histology. DNA was amplified from the V3-V4 regions of the 16S rRNA gene. In-vitro E-test was used to detect antibiotic resistance. Microbiome community analysis was conducted through α-diversity, β-diversity, and relative abundance.

Results
Sixty-nine H. pylori positive samples were eligible after quality filtering. Following resistance status to five antibiotics, samples were classified into 24 sensitive, 24 single resistance, 16 double resistance, 5 triple resistance. Samples were mostly resistant to metronidazole (73.33%; 33/45). Comparation of four groups displayed significantly elevated α-diversity parameters under the multidrug resistance condition (all P <0.05). A notable change was observed in triple-resistant compared to sensitive (P <0.05) and double-resistant (P <0.05) groups. Differences in β-diversity by UniFrac and Jaccard were not significant in terms of the resistance (P = 0.113 and P = 0.275, respectively). In the triple-resistant group, the relative abundance of Helicobacter genera was lower, whereas that of Streptococcus increased. Moreover, the linear discriminant analysis effect size (LEfSe) was associated with the presence of Corynebacterium and Saccharimonadales in the single-resistant group and Pseudomonas and Cloacibacterium in the triple-resistant group.

Conclusion
Our results suggest that the resistant samples showed a higher trend of diversity and evenness than the sensitive samples. The abundance of H. pylori in the triple-resistant samples decreased with increasing cohabitation of pathogenic bacteria, which may support antimicrobial resistance. However, antibiotic susceptibility determined by the E-test may not completely represent the resistance status.