bluuebunny/crossref_metadata_2025_split huggingface dataset:
Depresi Ibu Rumah Tangga Dengan Hiv/Aids Sebelum Dan Sesudah Diberikan Spiritual Emotional Freedom Technique (Seft)
Authors: Sugiartini Desak Ketut , Meriyani Dewi Aprelia 
Published: July 2023

ABSTRACTÂ Background of Study : Housewives infected with HIV / AIDS are very vulnerable to experiencing depression. Apart from low self-esteem, housewives also feel that they have never done risky behavior but can be infected with HIV / AIDS. So it is necessary to provide spiritual emotional freedom technique (SEFT). The purpose of this study was to see differences in levels of depression before and after being given SEFT and differences in levels of depression in mothers before and after being given SEFT and conventional counseling.Methods : This research design used a quasi experiment with a pre post test approach. Where the respondents are at least 30 respondents divided into 2 groups, namely the SEFT group and the conventional counseling group. The sampling technique was simple random sampling, then the inclusion and exclusion criteria were assessed. Treatment and control were given for 1 month with meetings 3 times a week. The results were analyzed using paired and independent t-test.Results : The results found were that there were differences before and after in the SEFT group. Meanwhile, there was no significant difference in the conventional counseling group. Then the average level of depression in the treatment group was lower by -8.27 compared to the pain intensity in the group without being given SEFT (conventional counseling) with p value <0.05 and 95% CI (-12.5- (-4.07).Conclusion : The conclusion is that there is an effect of SEFT on reducing the level of depression of housewives with HIV / AIDSÂ Keywords : Housewife, HIV/AIDS, Depression, SEFT
Kepatuhan Penggunaan Masker Pada Pedagang Lapak Sayur Sebagai Upaya Pencegahan Penyakit Covid-19 di Pasar Beringharjo Yogyakarta
Authors: Tursilowati Sri Yuni , Utami Silviana , Syamsinar Syamsinar 
Published: July 2023

ABSTRACTÂ Background of Study : COVID-19 is an infectious disease caused by the newly discovered corona virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been declared a world pandemic by WHO (WHO, 2020) since March 11, 2020 The spread of the COVID-19 outbreak is very fast and deadly, the transmission is transmitted through physical contact, mouth, eyes, and nose. Based on the results of the preliminary study, it is known that the compliance with the use of masks by traders at Beringharjo Market is still low, from 10 traders seen 3 people who do not wear masks and 5 people who wear masks when serving buyers after pinning them on their chins, and 2 people using masks.Methods : This type of research is quantitative with a cross sectional design. The research population was 93 vegetable stall traders at Beringharjo Market. Sampling using Total Sampling. Results : Knowledge is significantly related to compliance with the use of masks with Chi Square test results showing a significant value of P Value of (0.002) < (0.05), there is a correlation between attitude and adherence to the use of masks based on Chi Square test obtained a significant value of P Value of (0.007 ) < (0.05) and there is a correlation between supervision and compliance with the use of masks, but compliance with the use of masks is not related to gender.Conclusion : There is a correlation between knowledge, attitude, supervision and compliance with the use of masks, while the gender of traders is not significantly related to compliance with the use of masksÂ Keywords: Knowledge, Attitude, Supervision, Compliance, Masks, COVID-19
Hubungan antara Kebiasaan Sarapan dan Status Gizi dengan Kejadian Anemia pada Remaja di Kawasan Bantaran Kali Winongo Kota Yogyakarta
Authors: Hidayah Mudita Sri 
Published: July 2023

Background: Nutritional anemia is one of Indinesiaâ€™s major public health problems. Anemia in adolescent girls contributes to maternal and foetal mortality and morbidity in future. The purpose of this study is to determine the prevalence of anemia among adolescent in a slum area Kali Winongio and and to determine the influence of breakfast habbits and body mass index (BMI)Â associated with it.Methods: A community-based cross-sectional study was conducted among 62 adolescent in a slum area at Kali Winongo Yogyakarta from September to December 2019. Information regarding socio-demographic and breakfast habits was recorded in pre-designed. Hemoglobin estimation was done by HemoCue system. Data was analized by mean, deviation standard and chi-square test.Results: The percentage of anemia in adolescents was 29.03%. The greatest distribution of anemia incidence between 10-14 years age group. Most of them have a breakfast habit, which was 88.4%. Bivariate analysis showed that there was no significant relationship between gender, age (p = 0.14), nutritional status (p = 0.85), and breakfast habits (p = 0.93) with the incidence of anemia.Conclusion: there is no relationship between breakfast habits and nutritional status with the incidence of anemia. Breakfast not only needs to be familiarized but also needs to be considered the menu at breakfast.Keywords: anemia, breakfast habits, nutritional status
Literature Review: Pengaruh Terapi Musik terhadap Tekanan Darah Pasien Hipertensi
Authors: Akbar Adho Alif , Merdekawati Diah , Sari Lisa Anita 
Published: July 2023

Background of Study: Hypertension is one of the main causes of mortality and morbidity in Indonesia, hypertension treatment can be done pharmacologically and non-pharmacologically, to get low side effects, use complementary therapy, namely music therapy in lowering blood pressure, namely classical, Mozart music and instrumental music. This study aims to determine the effect of music therapy on reducing blood pressure. Methods: This study was conducted to collect data on several types of music therapy to lower blood pressure. This research done with collect from several research results to know as much information as possible from data obtained through Google Portal Garuda (IPI), while the research instrument used was observation sheets from journal articles that have been previously researched, namely classical music therapy and insrumental music. Results: Classical music therapy, Mozart music and instrumental music can reduce blood pressure. From the three types og music therapy, classical music therapy was the most effective. If it was done regularly so that music therapy can be used as non-pharmacological therapy to reduce blood pressure, and there was one journal which states that there was no effect of music therapy on effectiveness. Conclusion: Three music therapies that have been compared, the most effective music therapy for lowering blood pressure was classical music therapy. For this reason, it is expected to apply nursing interventions to patients with hypertension by using complementary therapy, namely music therapy.Keywords:Â Music therapy, hypertension
Pengaruh Edukasi Kesehatan Obesitas Melalui Audio Visual Aid (AVA) terhadap Perilaku Pasien Obesitas di Wilayah Puskesmas Melayu Kota Piring Kota Tanjungpinang
Authors: Nurhidayu Nurhidayu , Khariroh Syamilatul , Sartika Lili Sartika 
Published: July 2023

Background of Study: Obesity is an excessive accumulation of fat due to an imbalance of energy intake with energy used for a long time and has an impact on health problems and decreased quality of life. Health education using audio visual aid (AVA) can improve behavior change in obese patients towards a better understanding of health. This study aims to determine the effect of health education through audio visual aid (AVA) on behavioral changes in obese patients in Puskesmas Melayu Kota Piring.Methods: This research used Pre-experimental research design with One Group Pretest Post-test design. There were 20 respondents for sampling. The instrument data used questioner to measure knowledge, attitudes and actions about behavior change. Analysis data used Wilcoxon statistical test.Results: For statistical test knowledge indicators p-value = 0.055 (Ëƒ0.05), this showed that the alternative hypothesis (Ho) was rejected. As for the attitude indicator, the statistical test value of p-value = 0.025 (Ë‚0.05) and the indicator of statistical test action p-value = 0.004 (Ë‚0.05), this showed that the alternative hypothesis (Ha) was accepted. Conclusion: Health education through audio visual aid (AVA) can influence the behavior of obese patients.KeywordsÂ : health education, audio visual aid (AVA), obesity
Stres dan Kualitas Tidur dengan Kadar Gula Darah Puasa pada Lansia DM Tipe II
Authors: Nugraha Frestyan Setya , Yulitasari Brune Indah , Putri Tengku Isni Yuli Lestari 
Published: July 2023

Background: One of the important factors that occur in the elderly is decrease of health condition such as Diabetes Mellitus type II. This condition is supported by psychological conditions such as stress receptors of the elderly. High stress will affect the quality of sleep. Where stress and sleep quality affect blood sugar in the elderly to become unstable which can harm Diabetes Mellitus patients.Objective: This study aims to identify the correlation between stress levels and sleep quality with fasting blood sugar levels in the elderly suffering from Diabetes type II at the Kasihan II Public Health Center, Bantul, YogyakartaMethods: This research was descriptive-analytic research with a cross-sectional approach. The sample in this study was taken using a purposive sampling technique with 51 elderly respondents with Diabetes Mellitus type II. The research instrument used the Diabetes Distress Scale (DDS), the Pittsburgh Sleep Quality Index (PSQI), and the Glucometer.Results: The statistical test was used the Spearman rank test. The results in this study there was relationship between stress levels and sleep quality in the elderly with type II diabetes, it was evidenced by the P-value 0.000 (stress level with GDP) and P-value 0.003 (sleep quality with GDP).Conclusion: It can be concluded that there is a significant relationship between stress levels, sleep quality with fasting blood sugar levels in the elderly suffering from type II diabetes at the Kasihan II Public Health Center, Bantul, Yogyakarta.Keywords:Â DM Type 2, Elderly, Stress
STUDI KASUS: DUKUNGAN SUAMI PADA PROSES ADAPTASI PSIKOLOGI IBU NIFAS
Authors: Achmad Ismiyanti , Wabula Widy Markosia 
Published: July 2023

Secara psikologis ibu nifas memiliki perasaan mudah marah dan mudah sedih. Sebagian besar ibu pasca melahirkan sering merasa diabaikan oleh orang yang dicintainya, sehingga mengalami kecemasan yang kemudian berubah menjadi stress. Studi kasus ini menggambarkan Ny. M ibu nifas hari ke tiga yang merasa kelelahan dalam mengurus anak dan rumah tangga dan kurangnya dukungan suami. Upaya yang dilakukan adalah dengan memberikan penjelasan kepada Ny.M dan suami bahwa bahwa Ny. M berada pada peruode Taking hold yaitu Ny.M masih sangat membutuhkan bantuan dan dukungan dari orang-orang terdekatnya dalam merawat bayi. Asuhan kebidanan yang diberikan dapat mengurangi kecemasan yang dialami oleh ibu. Dukungan dan pendampingan dari keluarga dan berkelanjutan dari tenaga kesehatan sangat diperlukan untuk memperoleh hasil asuhan yang optimal.
Analysis of the Marketing Strategy of the New Product Innovation in the Highly Saturated Fast-Moving Consumer Good (FMCG) Market: Study Case: ABC Sweet Soy Sauce with Flavor from the Kraft Heinz Company in Indonesia)
Authors: Irawan Megawati , Dellyana Dina 
Published: July 2023

The Indonesian condiment market is highly competitive, with sweet soy sauce and chili being the dominant products. ABC Brand was one of the market leaders, but in the Sweet soy sauce market in the past ten years losing its leadership as it is seen as an old brand and no longer has strong differentiation from other brands. In response, KraftHeinz introduced a new innovative product called ABC Kecap Manis+, a sweet soy sauce with unique flavors like smoked beef and seafood, making it a highly innovative product in the market. This study aims to assess the performance of ABC Kecap Manis+ in the market, identify its challenges and opportunities, and provide recommendations for improvement. This study utilizes the marketing funnel and marketing mix frameworks. The study gathered data from internal company sources and conducted surveys using ABC Kecap Manis+ with smoke beef flavor as a representative. The analysis reveals that while the product innovation has achieved above-average penetration levels, trial conversion is low, and sales fluctuate depending on promotional support. The 6Ps marketing mix analysis highlights the product has an overall satisfactory performance. It has a strong perception of usage for meat and less for other dish variants. Meanwhile, based on the initial concept, the product aims for multipurpose use not limited to beef. The researcher proposes specific measures to address these challenges, including educating consumers about the product's usage and improving communication. A robust communication campaign centered around educating consumers about product usage. By implementing these recommendations, the researcher believes that KraftHeinz can enhance the overall performance of ABC Kecap Manis+ in the market and sustain its competitive advantage in the cooking aid category.
EDUKASI PEMBUATAN DAN DISTRIBUSI HANDSANITIZER DARI DAUN SIRIH KEPADA MASYARAKAT DI DESA HAULASI KECAMATAN MIOMAFFO BARAT
Authors: Pardosi Lukas , Siahaan Desta Gloria 
Published: July 2023

This activity was an education for making and distribution of handsanitizer made from natural ingredients, namely green betel leaf (Piper betle, L.), aloe vera (Aloe vera), lime (Citrus aurantifolia) and perfume to add fragrance to the handsanitizer . This activity was carried out for one day in Haulasi Village, West Miomaffo District, North Central Timor Regency, East Nusa Tenggara Province. Education on how to make and distribute handsanitizer s is carried out by visiting residents' houses door-to-door. The results of this activity were; 1) The community in Haulasi Village, West Miomaffo District, obtained information on how to make their own handsanitizer from natural ingredients. 2) People in Haulasi Village, West Miomaffo District knew how to use handsanitizer and the benefits of handsanitizer . 3) The handsanitizer can be used by the community to maintain hand hygiene to avoid the Covid-19 virus.
Analisis Variasi Mata Pisau Pada Mesin Pencacah Kulit Kelapa
Authors: Rahmadsyah  , Saktisahdan Tengku Jukdin , Pane Ali Hasimi , Saputra Dani , Hasanah Moraida 
Published: July 2023

Pengolahan kulit kelapa menjadi media tanam adalah usaha untuk meningkatkan nilai jual kulit kelapa itu sendiri. Untuk membuat kulit kelapa menjadi media tanam dibutuhkan mesin pencacah agar dapat menghancurkan kulit kelapa tersebut agar lebih halus dan efektif dalam penggunaannya. Dalam proses pencacahan, jumlah mata pisau mempunyai peranan yang sangat penting. Mesin pencacah yang digunakan mempunyai variasi jumlah mata pisau sebanyak 12, 15, dan 18. Serta daya motor penggerak yang digunakan sebesar 5,5 Hp dan putaran 3600 rpm. Penggunaan 18 mata pisau mendapatkan hasil yang terbaik dibandingkan jumlah mata pisau yang lain. Dari jumlah mata pisau 18 mendapatkan rata-rata hasil cacahan terbanyak yaitu 1,78 kg untuk setiap 2 kg yang dicacah dengan waktu tercepat selama 12 menit 27 detik atau 747 detik.
Antibacterial activity mechanism of coptisine against Pasteurella multocida
Authors: Zhang Rui , Tian Shuo , Zhang Tengfei , Zhang Wenting , Lu Qin , Hu Qiao , Shao Huabin , Guo Yunqing , Luo Qingping 
Published: July 2023

ObjectivePasteurella multocida is a widespread zoonotic pathogen that causes severe damage to the poultry industry. This study focused on the antibacterial effects and mechanism of action of coptisine against P. multocida.MethodsThe minimum inhibitory concentration and half maximal inhibitory concentration of coptisine against P. multocida was measured. Additionally, the effect of coptisine on growth, cell wall, activity of respiratory enzymes, soluble protein content and DNA synthesis were also analyzed. Finally, the effect of coptisine on gene transcription was determined using RNA sequencing.ResultsWe demonstrated that coptisine has a strong antibacterial effect against P. multocida, with a minimum inhibitory concentration of 0.125 mg/mL. Moreover, the measurement of the half maximal inhibitory concentration confirmed that coptisine was safe for the pathogen. The growth curve showed that coptisine inhibited bacterial growth. Measurement of alkaline phosphatase activity in the culture solution showed that coptisine affected cell wall permeability. Transmission electron microscopy revealed that coptisine chloride destroyed the cell structure. In addition, coptisine blocked the respiratory system, as measured by the levels of critical enzymes of the tricarboxylic acid cycle and glycolysis, succinate dehydrogenase and lactate dehydrogenase, respectively. Similarly, coptisine inhibited the synthesis of soluble proteins and genomic DNA. The KEGG pathway analysis of the differentially expressed genes showed that they were associated with cellular, respiratory, and amino acid metabolism, which were downregulated after coptisine treatment. Additionally, genes related to RNA degradation and the aminoacyl-tRNA pathway were upregulated.ConclusionIn this study, we demonstrated that coptisine exerts an antibacterial effect on P. multocida. These findings suggest that coptisine has a multifaceted impact on various pathways, resulting in the inhibition of P. multocida. Thus, coptisine is a potential alternative to antibiotics for the treatment of P. multocida infections in a clinical setting.
Markers of the ageing macrophage: a systematic review and meta-analysis
Authors: Moss Charlotte E. , Phipps Hew , Wilson Heather L. , Kiss-Toth Endre 
Published: July 2023

IntroductionAgeing research is establishing macrophages as key immune system regulators that undergo functional decline. Due to heterogeneity between species and tissue populations, a plethora of data exist and the power of scientific conclusions can vary substantially. This meta-analysis by information content (MAIC) and systematic literature review (SLR) aims to determine overall changes in macrophage gene and protein expression, as well as function, with age. MethodsPubMed was utilized to collate peer-reviewed literature relating to macrophage ageing. Primary studies comparing macrophages in at least two age groups were included. Data pertaining to gene or protein expression alongside method used were extracted for MAIC analysis. For SLR analysis, data included all macrophage-specific changes with age, as well as species, ontogeny and age of groups assessed. ResultsA total of 240 studies were included; 122 of which qualified for MAIC. The majority of papers focussed on changes in macrophage count/infiltration as a function of age, followed by gene and protein expression. The MAIC found iNOS and TNF to be the most commonly investigated entities, with 328 genes and 175 proteins showing consistent dysregulation with age across the literature. Overall findings indicate that cytokine secretion and phagocytosis are reduced and reactive oxygen species production is increased in the ageing macrophage.DiscussionCollectively, our analysis identifies critical regulators in macrophage ageing that are consistently dysregulated, highlighting a plethora of targets for further investigation. Consistent functional changes with age found here can be used to confirm an ageing macrophage phenotype in specific studies and experimental models.
Moderate hypoxia induces metabolic divergence in circulating monocytes and tissue resident macrophages from Berkeley sickle cell anemia mice
Authors: Lisk Christina , Cendali Francesca , Pak David I. , Swindle Delaney , Hassell Kathryn , Nuss Rachelle , George Gemlyn , Davizon-Castillo Pavel , Buehler Paul W. , D’Alessandro Angelo , Irwin David C. 
Published: July 2023

IntroductionHuman and murine sickle cell disease (SCD) associated pulmonary hypertension (PH) is defined by hemolysis, nitric oxide depletion, inflammation, and thrombosis. Further, hemoglobin (Hb), heme, and iron accumulation are consistently observed in pulmonary adventitial macrophages at autopsy and in hypoxia driven rodent models of SCD, which show distribution of ferric and ferrous Hb as well as HO-1 and ferritin heavy chain. The anatomic localization of these macrophages is consistent with areas of significant vascular remodeling. However, their contributions toward progressive disease may include unique, but also common mechanisms, that overlap with idiopathic and other forms of pulmonary hypertension. These processes likely extend to the vasculature of other organs that are consistently impaired in advanced SCD.MethodsTo date, limited information is available on the metabolism of macrophages or monocytes isolated from lung, spleen, and peripheral blood in humans or murine models of SCD.ResultsHere we hypothesize that metabolism of macrophages and monocytes isolated from this triad of tissue differs between Berkley SCD mice exposed for ten weeks to moderate hypobaric hypoxia (simulated 8,000 ft, 15.4% O2) or normoxia (Denver altitude, 5000 ft) with normoxia exposed wild type mice evaluated as controls.DiscussionThis study represents an initial set of data that describes the metabolism in monocytes and macrophages isolated from moderately hypoxic SCD mice peripheral lung, spleen, and blood mononuclear cells.