bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic analysis of porous fiber‐reinforced sandwich composite panel with variable angle
Authors: Sun Ruijun , Zheng Changsheng , Yang Fazhan , Zhang Jingjing , Zhou Yuesong , Li Xiang 
Published: January 2025

AbstractDamped sandwich composite structures are increasingly used in the aerospace, automotive and energy sectors due to their high damping and lightweight properties. Here, a novel porous fiber‐reinforced sandwich composite structure is proposed, by punching holes in fiber cloth with impregnated damping solution, and resin flows through the holes during the formation of the composite structure, connecting the upper and lower prepreg layers. This paper focuses on the theoretical study of the free vibration behavior of simply supported composite porous multilayer fiber‐reinforced sandwich composite structures with arbitrary delamination angles. The vibrational differential equation including the orientation angle was established and solved using Rayleigh‐Ritz method and Navier method. Subsequently, the Abaqus finite element method and modal test analysis were used to evaluate the dynamic performance of the structure with different orientation angles, verify the proposed theoretical model and solution strategy, and perform structural optimization based on a genetic algorithm. The results show that the panel with the area ratio of the damping layer of 94.854% and a fiber orientation angle of multiples of 45° has excellent dynamic performance. This model has significant advantages in improving structural stiffness and provides a theoretical basis for practical engineering applications.Highlights
A dynamic model of porous multilayer damping plate is established.
The effect of different fiber orientation angle on porous plate is studied.
An experimental platform is constructed to corroborate the theoretical accuracy.
Structural optimization of porous plate is conducted using a genetic algorithm.
The influence of structural parameters on the porous plate is analyzed.
Risk of Cord Entanglement After Iatrogenic Monoamnionicity, With Selective and Solomon Laser Treatment for Twin‐To‐Twin Transfusion Syndrome in Monochorionic Twin Pregnancies
Authors: Lanna Mariano , Palandri Ludovica , Faiola Stefano , Casati Daniela , Laoreti Arianna , Coco Chiara , Savasi Valeria , Consonni Dario 
Published: January 2025

ABSTRACTIntroductionFetoscopic laser surgery (FLS) is the gold standard treatment for monochorionic (MC) twin pregnancies complicated by twin‐twin transfusion syndrome (TTTS). The aim of our study was to evaluate the rate and risk factors for cord entanglement in the presence of iatrogenic monoamnioticity (iMA), a consequence of inadvertent septostomy during FLS.MethodsThis is a retrospective analysis of two consecutive cohorts of FLS performed either using the selective technique from January 2004 to January 2012, or with the Solomon technique, from that date onwards. Maternal and fetal characteristics, technical details, and obstetrical and perinatal outcomes were recorded. Cord entanglement was identified based on the presence of a galloping sign observed during prenatal ultrasound in the presence of iMA. At our center, mono‐amniotic twins are electively delivered at 32 completed weeks.ResultsThe mean gestational age of the 558 FLS, 52.3% selective and 47.6% Solomon, was 19.8 weeks (15.1–26.4). Solomon laser coagulation was associated with a lower occurrence of TAPS or TTTS (5.3% vs. 13%, p = 0.001) after the FLS and a higher number of placental abruption (9% vs. 2% p < 0.001) and by more cord entanglement in the presence of iMA (9.4% vs. 2.4% respectively, p < 0.001). The presence of iMA was correlated with a higher occurrence of limb defects (6.2% vs. 1% in non‐iMA twins, p 0.001).ConclusionsSolomon FLS was associated with a higher risk of cord entanglement and placental abruptio. As a consequence, we delivered twins with iMA earlier.
Predictors of Potentially Inappropriate Stimulant Prescribing Among Adults
Authors: Thakkar Pavan V. , Boutzoukas Angelique E. , Compton Scott N. , Sivashankar Ohviya , Zimmerman Kanecia O. , Benjamin Daniel K. , Brookhart M. Alan 
Published: January 2025

ABSTRACTPurposeIncreases in adult stimulant prescribing pose a potential risk due to the higher prevalence of contraindicated conditions among this population. We sought to identify patient, provider, and visit characteristics predictive of potentially inappropriate adult stimulant prescriptions.MethodsWe conducted a repeated cross‐sectional study using the National Ambulatory Medical Care Survey, a nationally representative weighted sample of 5 453 702 723 ambulatory care visits from 2012 to 2019. Potentially inappropriate prescriptions were defined as prescriptions to patients with potentially contraindicated conditions, as determined by US Food and Drug Administration stimulant labels.ResultsOf the 5 453 702 723 visits, stimulant use was prevalent at 121384694 (2.23%) visits and newly prescribed at 18880152 (0.34%) visits. Of these, 4 620 138 (24.47%) new stimulant prescriptions and 28 055 947 (23.11%) prevalent prescriptions were potentially inappropriate. Potentially inappropriate prescribing increased over time and with age. Visits to primary care providers (relative risk [RR] 1.65, 95% CI 1.05–2.59) were predictive of inappropriate prescribing. Non‐Hispanic Black (RR 0.48, 95% CI 0.33–0.70) and Hispanic race/ethnicity (RR 0.46, 95% CI 0.35–0.60), coronary artery disease (RR 0.54, 95% CI 0.33–0.86), pregnancy (RR 0.05, 95% CI 0.03–0.11), hypertension (RR 0.69, 95% CI 0.56–0.84), and glaucoma (RR 0.07, 95% CI 0.02–0.24) were predictive of decreased prevalent stimulant prescriptions; substance abuse was predictive of new stimulant prescribing (RR 2.14, 95% CI 1.07–4.27).ConclusionsThe proportion of potentially inappropriate adult stimulant prescriptions increased over time and with patient age. Visits to primary care providers were predictive of potentially inappropriate prescribing, and a history of substance abuse was predictive of new stimulant prescriptions; therefore, quality improvement interventions regarding safe stimulant prescribing practices may be warranted.
Prioritization and multilevel mapping of implementation strategies for a cancer rehabilitation navigation program
Authors: Stout Nicole L. , Harrington Shana E. , Perry Ashley , Alappattu Meryl J. , Manes Mindi R. 
Published: January 2025

AbstractBackgroundAlthough determinants and strategies for implementing a cancer rehabilitation navigation (CRNav) program have been described, defining specific implementation interventions could improve uptake in oncology care delivery. This manuscript shares prioritized implementation interventions using a multilevel framework.MethodsWe convened interdisciplinary stakeholders from two CRNav programs to participate in an implementation mapping focus group. Using a multilevel framework that considered provider‐, clinic‐, and system‐level interventions, the focus group discussion guide sought participant input on specific interventions that needed to occur at each level to facilitate implementation. The focus group transcript was analyzed using deductive thematic coding to identify program implementation interventions at each level. The interventions were then shared with all stakeholders to seek agreement and prioritization using a modified Delphi process. A priori a 70% threshold was established to define agreement. Two rounds of Delphi were conducted.ResultsFifteen stakeholders were recruited and nine participated in the focus group. The implementation mapping exercise identified 19 different interventions within the following Expert Recommendations for Implementing Change domains by level: provider level—use evaluative and iterative strategies, provide interactive assistance, train and educate stakeholders, support clinicians; clinic level—change infrastructure, support clinicians, adapt and tailor to context, use evaluative and iterative strategies; and system level—develop stakeholder interrelationship, use financial strategies, change infrastructure. Seven of 15 individuals completed both rounds of the Delphi. Fourteen interventions achieved agreement for high importance. Highest prioritized implementation interventions were develop a core champion team, develop a rationale for program justification, agree upon outcomes measures for the program, and examine and contextualize barriers that will influence the program.ConclusionClinical implementation of an innovative care delivery model requires attention to specific interventions that affect various levels within a health care system. These findings will inform future research and clinical efforts in the implementation of CRNav programs.
Removal of Tetracycline Antibiotic as a Hospital Waste by pH‐Sensitive Degradable Composite Hydrogel Using Fenton‐Like System
Authors: Dehghani Firoozabadi Ali , Eslami Hossein , Sabzevari Alireza , Ansari Mojtaba 
Published: January 2025

ABSTRACTFenton‐like hydrogels crosslinked with imine bond were prepared for the removal of tetracycline. Initially, the oxidation process of carboxymethyl cellulose (CMC) was performed, and it was named OX‐CMC. The confirmations were then obtained using NMR and FTIR analyses. The degree of CMC oxidation was investigated in relation to reaction time, and optimal time of 4 h was selected. In the second part, a pH‐sensitive hydrogel with imine bond was prepared from the crosslinking reaction between OX‐CMC and chitosan. The formation of the hydrogel through imine crosslinking was confirmed by FTIR spectroscopy. By increasing ratio of OX‐CMC to chitosan, the swelling rate for the hydrogel decreased. Turbidity measurements showed that a higher OX‐CMC to chitosan weight ratio resulted in slower hydrogel degradation in acidic environments. In the third part, Fe3O4 nanoparticles with concentrations of 5 and 10 wt% were incorporated into the hydrogel structure. TEM studies revealed a spherical morphology and uniform distribution of nanoparticles within the hydrogel network. SEM images revealed a porous structure which composed of interconnected pores in the hydrogel. The results of UV–visible spectroscopy indicated that the degradation of magnetic hydrogels would augment as magnetic nanoparticle content increases, pH decreases, and the hydrogen peroxide content increases.
Stress Management Program for Scanxiety in People With Advanced Lung Cancer: Intervention Adaptation and Stakeholder Feedback
Authors: Derry‐Vick Heather , Khoudary Amanda , Billini Osairys , Prigerson Holly G. , Schwartz Marc D. , Cohen Jeffrey , Griffin Chance , Gutierrez Martin , Lichtenthal Wendy G. , Carter‐Bawa Lisa 
Published: January 2025

ABSTRACTBackgroundAlthough scanxiety is common and impactful for people with advanced lung cancer, few interventions address this psychosocial concern.AimsTo create a stress management program for scanxiety.MethodsWe conducted a structured intervention adaptation process guided by the ADAPT‐ITT framework. We tailored materials from an existing evidence‐based program, drafted additional modules, and obtained feedback on initial content. Following content revisions and website prototype development, 21 participants (patients with metastatic lung cancer, n = 8; family members, n = 3; clinicians, n = 10) reviewed the program. Participants rated the program's acceptability (Acceptability of Intervention Measure; AIM), feasibility (Feasibility of Intervention Measure; FIM), appropriateness (Appropriateness of Intervention Measure; IAM), helpfulness (module Likert ratings), and usability (Post‐Study System Usability Questionnaire; PSSUQ), and completed semi‐structured interviews.ResultsData revealed positive impressions of the program. Participants rated the program as acceptable (89%), feasible (89%), and appropriate (95%; proportion with average ratings ≥ 4 out of 5 on AIM, FIM, and IAM respectively). They rated 6 of the 7 modules as helpful, appropriate, and fitting with their experience (77%–100% with Likert ratings ≥ 4 out of 5); the below‐threshold module (Introduction) was revised based on rapid qualitative analysis of interview data. Although 33% needed help to start using the website, its usability was rated highly after use (PSSUQ Mdn = 1.56, IQR = 1.11–1.82). The refined intervention is a largely self‐guided program to enhance stress management skills using psychoeducation, recorded on‐demand exercises, and 3 brief coaching calls.ConclusionsThis highly‐rated intervention has the potential to alleviate scanxiety among people with advanced lung cancer.
Mental Health Consequences of Opioid Pain Medication Use Behaviors and Motives Among Adolescents and Young Adults With Cancer: Results From a National Survey
Authors: Rogers Andrew H. , Pielech Melissa , Ketterl Tyler G. , Palermo Tonya M. 
Published: January 2025

ABSTRACTBackgroundAdolescents and young adults (AYA) with cancer experience long‐term consequences into survivorship that impact quality of life, including mental health symptoms, substance use, and persistent pain. Given the elevated rates of pain, AYA cancer survivors are at increased risk for opioid pain medication (OPM) exposure, increasing risk for opioid‐related negative consequences, particularly for those with mental health symptoms. Minimal research has documented that a considerable proportion of AYAs with cancer receive OPM that continues into survivorship, yet the lack of consensus on the definition of problematic opioid use coupled with the high clinical need for OPM makes it particularly challenging to understand the impact of OPM use in this population.AimsTherefore, the current study examined differences in opioid pain medication use, use behaviors, and motives between AYA cancer survivors and non‐cancer controls.MethodsUsing the National Survey on Drug Use and Health, we tested the impact of OPM use behaviors and motives on depressive symptoms and mental healthcare utilization variables.ResultsResults show that, compared to non‐cancer controls, AYA cancer survivors evince higher rates of opioid use, behaviors, and pain relief motives. Within the cancer survivor group only, there were differential patterns of associations between OPM behaviors, motives, depressive symptoms, and mental healthcare utilization, with using opioid pain medication for emotion coping/to get high showed the largest effect sizes with outcome variables.ConclusionsThe results highlight the importance of moving beyond use itself and examining how and why AYAs with cancer are using opioids to understand potential negative consequences.
Improving Permafrost Mapping in Southern Tibetan Plateau Using Machine Learning and Rock Glacier Inventory
Authors: Yan Dezhao , Feng Min , Hu Zhongyi , Xu Jinhao , Li Xin 
Published: January 2025

ABSTRACTAs a key component of the cryosphere, permafrost is sensitive to climate change, but mapping permafrost, especially in the Tibetan Plateau, has been challenging due to the heterogeneous mountainous landscape and limited representativeness of ground observations. Using 155 compiled ground observations and more than 20,000 rock glacier records, we developed a machine learning model to map the distribution of permafrost and produce an improved permafrost zonation index (PZI) map. The model was applied by incorporating several control variables, including terrain (elevation and relief), soil (bulk density, clay, coarse fragments, sand, and silt), and temperature (MAAT, FDD, and TDDT) to estimate the PZI at a 1‐km resolution in the southern Tibetan Plateau. Excluding glaciers and lakes, the area of permafrost estimated by the new map is approximately 103.5 × 103 km2, accounting for 47.8% of the total area of the region. The result was assessed with various datasets and compared with existing permafrost maps and achieved higher accuracy compared with previous studies. The overall classification accuracy was 96.1% in high plain areas and 84.4% in mountain areas. The results demonstrated the substantial potential for improving mapping permafrost and understanding the periglacial environment with rock glacier inventories and machine learning, especially in complex terrain and climate.
Proprioception After Unilateral Stroke: Changes in the Affected and Unaffected Lower Limbs Over Time
Authors: Xu Jinyao , Witchalls Jeremy , Preston Elisabeth , Pan Li , Zhang Gengyuan , Waddington Gordon , Adams Roger , Han Jia 
Published: January 2025

ABSTRACTBackgroundProprioceptive deficits are common among stroke survivors and can negatively impact their balance and postural control. However, there has been little evaluation of the change in proprioceptive deficits in the lower limbs over time after stroke. This study aimed to examine proprioceptive deficits over time after stroke in both the affected and “unaffected” lower limbs.MethodsThis cross‐sectional study included sixty first‐time unilateral stroke survivors and twenty age‐matched healthy individuals. Participants after stroke were divided into three subgroups based on different time points after stroke. The generally accepted clinical time points after stroke are the first 4 weeks—the acute stage; 5–24 weeks—the subacute stage; over 24 weeks—the chronic stage. The active movement extent discrimination apparatus (AMEDA) was used to quantify ankle proprioception in plantarflexion and inversion directions, on both the affected and “unaffected” sides.ResultsLower limb proprioception scores decreased linearly over time after stroke on both the affected and “unaffected” sides (p < 0.001). Overall, proprioception scores for the stroke groups were significantly lower than those for the healthy age‐matched group (p < 0.01), with the only exception being ankle plantarflexion and inversion scores on the unaffected side in the acute stroke group, which were not significantly different from their healthy counterparts.ConclusionAnkle proprioception in both lower limbs decreased over time after a unilateral stroke, with proprioceptive acuity on the “unaffected” side diminishing linearly in the same way as that on the affected side. These observed continuing deficits in lower limb proprioception among stroke survivors raise implications for clinical neurorehabilitation.
Astragaloside IV Relieves Central Sensitization by Regulating Astrocytic ROS/NF‐κB Nuclear Translocation Signaling in Chronic Migraine Male Rats
Authors: Zhang Wei , Yang Yunping , Zhang Xiaoyan , Zhao Lilin , Zhou Jiying , Ji Lichun , Chen Lixue 
Published: January 2025

ABSTRACTChronic migraine (CM) is a disabling neurological disease. Astragaloside IV (AS‐IV), a natural product derived from Astragalus membranaceus, shows great potential in treating chronic pain by relieving inflammation and oxidative stress. This study aimed to investigate the effects and mechanisms of action of AS‐IV on CM. An inflammatory soup comprising histamine, bradykinin, serotonin, and prostaglandin E2 was used to establish a CM rat model, while lipopolysaccharide was applied to induce an inflammatory response in primary astrocytes. Pain threshold measurements were used to evaluate nociceptive hypersensitivity, while qPCR and Western blotting were applied to detect inflammatory indicators and synaptic protein expression, and Golgi‐Cox staining was applied to observe dendritic spine density, while transmission electron microscopy was used to observe synaptic ultrastructure. Mitochondrial function and oxidative stress were assessed using JC‐1 staining, Mitotracker staining, reactive oxygen species (ROS) quantification, and glutathione content. AS‐IV pretreatment alleviated central sensitization and ameliorated astrocyte activation and neuroinflammation. AS‐IV pretreatment alleviated mitochondrial dysfunction in vitro, and reduced the nuclear translocation of NF‐κB and the production of IL‐1β, which were reversed by ROS scavengers in vitro or mitochondrial respiratory chain disruptors in vivo. Our study indicates that AS‐IV can inhibit neuroinflammation by alleviating astrocyte mitochondrial dysfunction to mitigate central sensitization in CM, thereby providing an experimental basis for AS‐IV and A. membranaceus in CM prevention and treatment.
Preparation of Novel H3PO4 Mixed Sludge‐Sunflower Seeds Husk Biochar and its Application in TC Removal
Authors: Rahmoune Hafidha , Dahlab Soundous , Nasser Mohamed , Abomunassar Sundus Ahmed Mohsen , Guo Jifeng 
Published: January 2025

AbstractThis study primarily focuses on creating a new biochar substance using a combination of sewage sludge and sunflower seed husk. The biochar shows significant efficacy in eliminating tetracycline (TC). The characteristics of biochar, such as SEM, XPS, FT‐IR, and BET, were investigated respectively. After H3PO4 was added to change the surface, the novel biochar exhibited a porous and stiff surface, a larger specific surface area, and more carboxylic acid functional groups. Consequently, the activated biochar exhibited a higher adsorption capacity for TC than the pristine biochar, with values of 39.57 mg/g and 15.74 mg/g, respectively. The pseudo‐second‐order kinetics could describe the sorption of TC on PBCSS and BCSS well (R2 for PBCSS and BCSS is 0.876 and 0.824, respectively). The adsorption process was described using the Langmuir, Freundlich, and Dubinin–Radushkevich adsorption isotherms. Chemical adsorption helps TC and biochar stick to each other. Donor‐acceptor interactions, hydrogen bonds, and electrostatic interactions all make this possible. The study showed that the new biochar has the potential to be an economical adsorbent for the removal of TC from wastewater.
Synthesis of a Hierarchical FeBTC/FeS Structure with Enhanced Water Stability for Environmental Remediation
Authors: Souza Brenand A. S. , Freitas Denilson V. , Coelho Igor , Stavale Fernando , Guzzo Pedro L. , Machado Giovanna , Navarro Marcelo 
Published: January 2025

AbstractAn iron metal‐organic framework (MOF) was synthesized and tested for the photocatalytic degradation of organic dyes using methylene blue (MB) standard. The iron 1,3,5‐benzenetricarboxylate (BTC) MOF was synthesized using a simple and low‐cost electrochemical method, aligned with the green chemistry principles, 64% yield. FeBTC was modified in the presence of Na2S solutions (0.01 and 0.02 mmol L−1), giving FeBTC/FeS composites. SEM analysis showed the MOF structure preservation and the homogeneous dispersion of the sulfur on the composite surface. FeBTC MOF and FeBTC/FeS composites were characterized by XRD, FTIR, TGA, EDX, XPS, and EPR spectroscopy. The FeBTC MOF exhibited 25.1% of MB removal by adsorption (dark), whereas 43.4% (removal/degradation) was observed under simulated solar light. The modification with Na2S promoted the formation of composites containing iron polysulfide species, as observed by XPS. The FeBTC/FeS‐1 and FeBTC/FeS‐2 composites showed superior performance, achieving MB removal efficiencies of 86.0% and 82.4%, respectively, after an irradiation time of 120 min. Compared to photo‐Fenton processes, FeBTC and FeBTC/FeS‐1 composite demonstrated MB removal efficiencies of 96.9% and 99.6%, respectively. Thus, the FeBTC photocatalytic activity was increased by iron polysulfides formation on the MOF structure. FeBTC/FeS‐1 composite exhibited excellent adsorptive/photocatalytic activity, demonstrating its decolorizing potential for MB‐containing effluents.