bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possible future selves in STEM: an epistemic network analysis of identity exploration in minoritized students and alumni
Authors: Fan Yiyun “Kate” , Barany Amanda , Foster Aroutis 
Published: March 2023

AbstractBackgroundSTEM minority participation programs have been widely implemented in higher education with the goal of diversifying the global STEM workforce. Informed by research highlighting the potential of targeted exploration of STEM roles and reflection on theselfin relation to STEM (identity exploration), this work examines how engagement in a government funded STEM minority participation program shaped these processes in current students and program alumni.ResultsEpistemic network analysis (ENA) was used to visualize conceptual connections between identity themes that emerged from interviews with present and past program participants. Network models were developed for current students and alumni for cross-group comparisons. Differences were found in how participants at different stages of their careers enact and describe their identity exploration processes. Summative network models highlighted how students discussed action-taking (sometimes through participation in STEM minority program initiatives) as they explored less-certain possible future STEM roles, while alumni integrated more diverse and holistic facets of their identities when conceptualizing their futures. To close the interpretive loop, a qualitative interpretation of interview discourse was used to give context to network patterns.ConclusionsResults highlight the differences between novices’ and professionals’ conceptualizations of their future selves and illustrate how minoritized individuals describe their long-term patterns of identity exploration related to STEM majors and careers. Implications for future STEM identity research and practice, including higher education programming as a tool to support students’ STEM identity exploration processes, are discussed.
CMC development of [14C]-labeled sotorasib for the conduct of microtracer human ADME study
Authors: Sharma Sonika , Agarwal Prashant , Parsons Andrew T. , Huckle James E. , Correll Tiffany L. 
Published: March 2023

AbstractHuman absorption, distribution, metabolism, and excretion (hADME) studies of new drugs are required for global regulatory filings. Recent advances in high sensitivity analytical technologies have enabled microtracer hADME studies wherein very low radioactive doses can be administered to healthy volunteers to study drug pharmacokinetic profile. Microtracer hADME studies are advantageous to accelerate study timelines during drug development. However, there are limited examples in peer-reviewed journals that highlight the key chemistry, manufacturing, and control (CMC) development challenges and requirements for enabling these clinical microtracer hADME studies. The current manuscript summarizes the CMC activities, risk assessment, and mitigation strategies that were put in place and executed to enable and accelerate the microtracer hADME study of [14C]-labeled sotorasib (AMG 510, compound 1). Sotorasib is a first in class KRASG12C inhibitor used to treat non-small cell lung cancer (NSCLC) in patients with a KRASG12Cmutation (Canon et al., Nature 575:217–223, 2019). The key CMC activities included the synthesis of low nanocurie [14C]-labeled AMG 510 drug substance, development of a drug-in-bottle (DIB) formulation, use of simulation software to predict absorption profiles, associated drug substance and drug product analytical control strategies development, and the utilization of accelerator mass spectrometry (AMS) as a CMC tool enabling low radioactive strength formulation analysis.
Prevalence of insomnia in a sample of Internet addicts in different age groups in Abu Dhabi, UAE
Authors: Shaheen Somaya H. , Abdullah Eman Ahmed , Razik Mohammed M. Abdel , Mostafa Nehal 
Published: March 2023

Abstract
Background
Internet addiction, insomnia, and depression have a major health concern. The association of these problems can severely affect education, work productivity with negative outcomes for society. Internet addiction has been reported to be associated with insomnia and depression that may differ by age. The aim of the study is to assess the prevalence of insomnia and depression and their correlation with Internet addiction in all age groups and to detect age differences. A total of 386 participants were recruited. Data were collected using an online survey that contains questions about sociodemographic, Insomnia Severity Index (ISI), Internet Addiction Test (IAT), and Patient Health Questionnaire (PHQ9) to measure insomnia, Internet addiction, and depression, respectively.

Results
The overall prevalence of clinically significant insomnia was 22.5% while subthreshold insomnia was present in 38.5%. There was a significant negative correlation of age with IAT and PHQ9. Also, a highly significant positive correlation was found between ISI, IAT, and PHQ9 within the total sample and each age group (p = 0.000).

Conclusions
A great proportion of the general population suffers from insomnia, Internet addiction, and depression, and their prevalence rates differ by age. Also, there is a strong association between them. Identifying these problems is important, and interventions should include the three problems.
The Body is (Not) the Land
Authors: Madarieta Ethan 
Published: March 2023

AbstractThis article concerns the ongoing hunger and death strikes of the Mapuche, Indigenous peoples whose territories, or Wallmapu, are currently settler-occupied territories of south-central Chile and southwestern Argentina. It argues that these hunger strikes are acts of territorial precedent and corporeal autonomy that stand in opposition to the continuum of Chilean racism and its myriad devastating sociocultural and ecological effects. These hunger strikes wrest the ordering of life, and the processes and temporality of dying, from the state. In this way, the hunger strikes directly intervene in state claims to biopolitical and territorial sovereignty imposed via the settler metonymy that conflates the Mapuche body and land in order to dispossess them of a “proper” relation with land. In arguing that the Mapuche hunger strike is also an embodied and discursive precedent for territorial repossession within Mapuche kimün (knowledge), this article complicates assertions of the body as land and questions the very foundations of Chile's recursive claims to territorial sovereignty and the possibility of Mapuche territorial reclamation juridically. The Mapuche hunger strike thus should not be solely, or primarily, framed as resistance to an ongoing colonialism but rather as ongoing acts of corporeal autonomy and the establishment of body-land relationality as territorial precedence.
Revisiting and Recreating the Strike
Authors: Vega Cristina , Phillips Tara 
Published: March 2023

AbstractSince 2016, feminist mobilizations have reactivated the practice of the strike. Some countries have experienced mass expressions of it; in others, the term was simply adopted and with it a forceful idea: the power of social disruption. Partial strikes were carried out around the world with varying degrees of support, as were sit-ins, marches, actions, and calls to stop the various productive and reproductive circuits in which women are involved on a daily basis. For feminists the call to strike entails a number of pressing problems, since traditional models of the strike do not account for reproductive and other forms of unwaged or marginalized labor. The question then becomes what kind of strike would best serve those who tirelessly perform the labor of social reproduction and who at the same time are most denigrated and devalued. Yet looking back on the history of the strike, we are reminded that many strikes were connected to elements of working-class life that did not directly concern production. Looking to recent historical instances of the feminist strike recorded in the visual archive, this article seeks to broaden the feminist understanding of the strike by uncovering how women have used it on their own terms and in their own ways to effect change.
Hit the Tire
Authors: Pithouse Richard 
Published: March 2023

AbstractThe meaning of the strike has evolved across space and time. In contemporary South Africa it has come to include the road blockade, which is now a ubiquitous tool of popular politics in general and forms of politics organized from shack settlements in particular. This essay, drawing on many years of participation in popular politics in the city of Durban, shows that the road blockade is often, although not always, articulated to a politics presented in the language of dignity and marked by defiant humanism.
Lego® bricks assisted training of the novice debriefers
Authors: Capogna Emanuele , Ingrassia Pier Luigi , Capogna Giorgio 
Published: March 2023

Lego® Serious Play® is a guided workshop in which participants construct Lego creations to represent symbolic and metaphorical ideas in response to assignments. How to encourage inexperienced debriefers to concentrate on dialogue and communications strategies rather than engage in an unstructured debate on technical or behavioral abilities is one of the main challenges in training people to debrief a high-fidelity simulation session. We explore the use of Lego bricks in this study to build straightforward, standardised situations that debriefers in training can use to practice leading discussion. With this method, the different debriefing methodologies may be practiced focusing exclusively on method and dialogue, without getting involved or having to concentrate on the technical aspects.
In Their Own Words: Student Perceptions of Technical Poetry Writing in Discipline-Specific Undergraduate Engineering Courses: Opportunities and Challenges
Authors: Akçalı Elif , Williams Jade , Burress Rachel , Aguila Albert , Buraglia Mariana 
Published: March 2023

Although some studies have incorporated poetry into engineering courses, no studies exist that explore the use of writing poetry about technical topics to develop creative thinking skills in undergraduate engineering education. This study explores engineering students’ perceptions of incorporating poetry writing within an upper-level discipline-specific engineering course. Two research questions are considered: (RQ1) Do students think that the poetry assignments will be beneficial to their careers? (RQ2) What beneficial gain, if any, do students report from the poetry assignments? Sixty-one students from an industrial and systems engineering course at the University of Florida completed a four-question, open-ended survey. Data were qualitatively coded and analyzed. For RQ1, 63.3% of participants considered the assignment beneficial to their future engineering careers, 13.3% did not see it as beneficial, and 23.3% were uncertain. For RQ2, 11 code categories and four themes emerged; three themes addressed benefits related to professional skills (creative thinking, problem-solving, communication) and one theme suggested the enhancement of technical skills via deepened conceptual knowledge acquisition. Poetry writing on technical topics has the potential to cultivate creative thinking skills in upper-level discipline-specific courses in undergraduate engineering education. Additional research is warranted. Funding: This work was supported by the University of Florida Creative Campus Program as well as The Cottmeyer Family Innovative Frontiers Faculty Fellowship awarded to E. Akçalı. Supplemental Material: The e-companion is available at https://doi.org/10.1287/ited.2023.0284 .
Childbirth experiences for women in a Kenyan county referral hospital
Authors: Okwako Joseph Mukobe 
Published: March 2023

Background/AimsA woman's experience of childbirth can be positive or negative, although pregnant women have the right to a positive experience. A woman's experience should be fulfilling, and meet expectations that may be informed by personal and sociocultural beliefs. This study aimed to explore women's childbirth experiences at a county referral hospital.MethodsThis study used a transcendental phenomenological design. A total of 11 postnatal women were recruited until data saturation was achieved. Data were collected using semi-structured interviews and responses were recorded. Data were transcribed and manually coded, and major themes and sub-themes were identified using thematic analysis.ResultsWomen reported unbearable and traumatic labour pain with little intervention from caregivers. The majority of women had friendly and caring midwives as well as a clean and spacious postnatal ward. This experience shaped their courage, self-belief and the desire for a subsequent pregnancy and birth.ConclusionsGenerally, most women had a positive and satisfying childbirth experience despite labour pains. To ensure an optimally positive childbirth experience for all women, there is a need to promote privacy, comfort and respectful maternity care while offering alternative labour pain management.
The impact of COVID-19 variant 501Y.V2 on maternal and perinatal mortality among pregnant South African women
Authors: Basu Jayati Kusari , Chauke Lawrence , Magoro Terrance 
Published: March 2023

Background/Aims The COVID-19 variant SARS COV 501Y.V2 was responsible for the second wave of COVID-19 in South Africa from October 2020 to March 2021. There are no studies that report on maternal mortality from this variant globally. This study's aim was to determine the impact of the variant on maternal deaths in the Ekurhuleni health district, South Africa. Methods A retrospective record review of all maternal deaths in COVID-19 positive cases in the Ekurhuleni health district from October 2020 to March 2021 was conducted. Demographic details, comorbidities and obstetric data were assessed. Results A total of 11 women who tested positive for COVID-19 died. In these cases, there were high rates of hypertension (67%), stillbirth (50%) and preterm caesarean section (67%). Laboratory abnormalities, including anaemia (64%) and high levels of lactic dehydrogenase (100%), aspartate transaminase (67%) and D-dimer (80%), were observed. Conclusions This study adds to the growing global knowledge of COVID-19 infections. Routine COVID-19 testing of all comorbid pregnant women at each antenatal visit is recommended. All pregnant women should be counselled to follow strict COVID-19 prevention protocols.
‘I want us to divorce so that I will stay alone and be free’: the social experiences of women living with advanced cervical cancer in Ghana
Authors: Hobenu Kafui Abra , Naab Florence , Amakpa Eric 
Published: March 2023

Background/Aim Cervical cancer is the second most common form of cancer and second leading cause of mortality for women in Ghana, with most being diagnosed at the advanced stage. A late diagnosis affects women's social wellbeing. However, there is a dearth of information on the social implications of advanced cervical cancer among women in Ghana. This study's aim was to explore these social experiences. Methods A qualitative exploratory descriptive approach was used. Purposive sampling was used to recruit 15 women aged 33−67 years old who had been diagnosed with advanced cervical cancer. Data were collected through face-to-face interviews using a semi-structured interview guide. Data were analysed using content analysis. Results Four themes emerged: impaired relationships, social isolation, economic burden and support networks. Participants found that their diagnosis impacted their relationships with their partners and their family. They also reported isolating themselves from social events, either as a result of others' attitudes once they learnt of the diagnosis, or because of the symptoms of the disease and side effects of treatment that affected their physical appearance. The cost of treatment and living expenses, as well as the impact on women's ability to work, had considerable effects on the participants' lives. Many participants had the support of their spouse, family and place of work, although some reported a lack of support from their partner or coworkers. Conclusions The findings highlight the need to formulate policies to support women diagnosed with advanced cervical cancer to improve social wellbeing. A public awareness campaign is needed to educate the public to encourage acceptance of women living with advanced cervical cancer.
Readiness of Higher Education Institutions for Horizontal Typology, Institutional Sustainability and Quality Assurance
Authors: Ormilla Rashid Ceazar Galanto , Dupra Eileen Baptista 
Published: March 2023

<p style="text-align: justify;">This study was undertaken to assess the level of readiness of higher education institutions (HEIs) for horizontal typology, institutional sustainability, and quality assurance in the key result areas (KRAs) for the enhancement of mechanisms, systems, and policies for the HEIs’ effective operation. It is a descriptive correlational design using the modified self-evaluation document (SED). The study showed that all the seven HEIs that participated in this study had been operating for 40 years and above, offering more than sixteen program courses with more than sixteen accredited programs. Four of the HEIs were Level 2 in accreditation status and five were ISO Certified. The level of readiness of HEIs for horizontal typology was moderately ready, which means the HEIs need some improvements in horizontal typology. The most identified challenges affecting the level of readiness of HEIs in horizontal typology were the lack of innovation, technology, and sustainability; the lack of administrative strategies, leadership competencies, and management skills; and the lack of financial allocation for institutional development and advancements, respectively. There is no significant relationship between the institutional profile and terms of observing the standards in the KRAs. The study recommends further re-assessing the level of readiness of the HEIs in terms of documentation/evidence, observance for the improvement of the systems, processes and practices towards a more effective and efficient delivery of academic services to young people by conducting the more focused study in every KRAs and institutional self-assessment as future researches for the further improvement of the operations of HEIs.</p>
PRE-EXISTING KNEE OSTEOARTHRITIS AND JOINT DEPRESSION ARE ASSOCIATED WITH TOTAL KNEE ARTHROPLASTY REQUIREMENT AFTER TIBIAL PLATEAU FRACTURE IN PATIENTS ≥60 YEARS OF AGE
Authors: Gupta S. , Sadczuk D. , Riddoch F. , Oliver W. , Davidson E. , White T. O. , Keating J. F. , Scott C. E. H. 
Published: March 2023

We aimed to determine the rate of and risk factors for post-traumatic osteoarthritis (PTOA) and total knee arthroplasty (TKA) requirement after operative management of tibial plateau fractures (TPF) in older adults.We conducted a retrospective cohort study of 182 operatively managed TPFs in 180 patients ≥60 years old over a 12-year period with minimum follow up 1 year. Data including patient demographics, clinical frailty scores, mechanism of injury, management, reoperation and mortality were recorded. Radiographs were reviewed for: Schatzker classification; pre-existing knee osteoarthritis (KOA); severe joint depression >15mm; and development of PTOA. Kaplan Meier survival analysis was performed. Regression analysis was used to identify risk factors for radiographic indication for TKA and actual TKA.Forty-seven percent were Schatzker II fractures. Radiographic KOA was present at fracture in 32.6%. Fracture fixation was performed in 95.6% cases and acute TKA in 4.4%. Thirteen patients underwent late TKA (7.5%). At five-years, 11.8% (6.0-16.7 95% CI) had required TKA and 20.9% (14.4-27.4 95% CI) had a radiographic indication for TKA. Severe joint depression and pre-existing KOA were associated with worse survival for endpoints radiographic indication for TKA and actual TKA. Severe joint depression (HR 2.49(1.35-4.61 95% CI), p=0.004), pre-existing KOA (HR 2.23(1.17-4.23), p=0.015) and inflammatory arthropathy (HR 2.4(1.04-5.53), p=0.039) were independently associated with radiographic indication for TKA.In conclusion, severe joint depression and pre-existing arthritis are independent risk factors for both severe PTOA and TKA after TPFs in older adults. These features should be considered as an indication for primary management with acute TKA.
MalVulDroid: Tracing Vulnerabilities from Malware in Android using Natural Language Processing
Authors: Garg Shivi , Baliyan Niyati 
Published: March 2023

The Android operating system is often inflicted with mobile malware attacks, which occur due to some system loopholes or vulnerabilities. One malware can exploit numerous vulnerabilities and multiple malware can exploit a single vulnerability, thus, causing many-to-many ( X : Y ) mapping between malware and vulnerability. Therefore, it is crucial to understand malware behaviour to reduce the vulnerabilities. This paper presents the concept of a “MalVulDroid” framework that maps malware to vulnerabilities using a two-dimensional matrix. The many-to-many ( X : Y ) mapping matrix is obtained by using natural language processing techniques such as Bag-of-Words (BoW) leveraging n-gram probability generation and term frequency-inverse document frequency (TF-IDF), in addition to supervised machine learning classifiers such as multilayer perceptron (MLP), a support vector machine (SVM), a ripple down rule learner (RIDOR), and a pruning rule-based classification tree (PART). This study is the first of its kind where malware-to-vulnerability mapping can be leveraged to measure the rigorousness of unknown vulnerabilities and malware during the early phases of application development. The study considers extensive datasets such as Androzoo, AMD, and CICInvesAndMal2019 with 150 malware families and 48,907 malware samples, and nine major vulnerabilities affecting Android. MalVulDroid exhibits highly promising results with an accuracy of 98.04% for unigrams, and precision and F1-scores of over 90% using ensemble classifiers.
Programa QualityCoast: Estudios piloto en dos destinos de sol y playa
Authors: Fernández-Palacios Yaiza , Cecilia-Ruano Candelaria , Haroun Ricardo J. , Cózar Eduardo , De la Peña Pablo , Ferreira Maria , Pickaver Alan , Salman Albert 
Published: March 2023

En el marco del las actividades de cooperación inter- nacional de la Red de Prácticas Costeras (CoPraNet), una red INTERREG IIIC, se ha logrado el desarrollo de un programa de calidad internacional para destinos turísticos costeros – QualityCoast –.El Programa QualityCoast para destinos costeros certifica a un municipio, condado o región que demuestre un trabajo activo por una gestión más responsable y soste- nible. La implementación del Programa QualityCoast se determina mediante una serie de indicadores denomina- dos Hitos QualityCoast (QCMs), que señalan la calidad de la información disponible a los usuarios. Los QCMs se agrupan en las áreas temáticas de naturaleza, capacidad de carga, calidad ambiental y del agua y socio-economía. Se ha incorporado una categoría denominada ‘Otros’, con el fin de permitir la inclusión de criterios relevantes a áreas particulares no incluidas en los cuatro grupos principales. Este trabajo presenta el Programa QualityCoast, una de las contribuciones y resultaos principales de CoPraNet y, en particular, los resultados de las actividades piloto desarrolladas en distintas áreas de la Isla de Fuerteventura (Islas Canarias) y en el Municipio de Calvià (Islas Baleares), destinos maduros de sol y playa en España. Se ha hallado que este sistema de certificación puede ser de interés para este tipo de destinos.