bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fusobacterium sphaericum sp. nov., isolated from a human colon tumor, adheres to colonic epithelial cells and induces IL-8 secretion
Authors: Zepeda-Rivera Martha A. , Eisele Yannick , Baryiames Alexander , Wu Hanrui , Mengoni Claudia , Piccinno Gianmarco , McMahon Elsa F. , LaCourse Kaitlyn D. , Jones Dakota S. , Hauner Hans , Minot Samuel S. , Segata Nicola , Dewhirst Floyd E. , Johnston Christopher D. , Bullman Susan 
Published: June 2023

AbstractCancerous tissue is a largely unexplored microbial niche that provides a unique environment for the colonization and growth of specific bacterial communities, and with it, the opportunity to identify novel bacterial species. Here, we report distinct features of a novelFusobacteriumspecies,F. sphaericum sp. nov.(Fs), isolated from primary colon adenocarcinoma tissue. We acquire the complete closed genome and associated methylome of this organism and phylogenetically confirm its classification into theFusobacteriumgenus, withF. perfoetensas its closest neighbor.Fsis phenotypically and genetically distinct, with morphological analysis revealing its coccoid shape, that while similar toF. perfoetensis rare for mostFusobacteriummembers.Fsdisplays a metabolic profile and antibiotic resistance repertoire consistent with otherFusobacteriumspecies.In vitro, Fshas adherent and immunomodulatory capabilities, as it intimately associates with human colon cancer epithelial cells and promotes IL-8 secretion. Analysis of the prevalence and abundance ofFsin >20,000 human metagenomic samples shows that it is a low-prevalence member within human stool with variable relative abundance, found in both healthy controls and patients with colorectal cancer (CRC). Our study sheds light on a novel bacterial species isolated directly from the human CRC tumor niche, and given its interaction with cancer epithelial cells suggests that its role in human health and disease warrants further investigation.
The adoption of mobile payment services by millennials: the roles of smartphone addiction and situational variables
Authors: Shaw Bijeta , Roy Sanjit K. , Kesharwani Ankit , van Doorn Sebastiaan , Japutra Arnold 
Published: June 2023

PurposeThe increased usage of smartphones has made mobile payment services (MPS) popular among millennials, but it is uncertain if this shift in behavior is temporary due to situational factors like the pandemic or a long-term trend due to technological advances. This study uses the diffusion of innovation (DOI) literature to assess an integrated model including smartphone addiction, technology-related and consumer-related factors that influence consumers' intention to use MPS. It also explores the interplay of situational variables and smartphone addiction in shaping this relationship.Design/methodology/approachThe authors base the conceptual model on the theory of rational addiction and the theory of optimal flow. This model is then empirically validated through data collected from seven hundred users of MPS in India. Research hypotheses are tested using structural equation modeling and multi-group analysis.FindingsThe study finds that smartphone addiction has a positive impact on millennials' perceived advantages, compatibility, trialability and observability of MPS but does not significantly affect their perceived complexity or risk. The results also suggest that the relationship between smartphone addiction and MPS is moderated by situational factors. In low-priority situations, smartphone addiction strengthens millennials' perceptions and intentions to use MPS, while in high-priority situations, situational factors overshadow the impact of smartphone addiction.Originality/valueThe findings of the study enable organizations to capitalize on smartphone addiction-driven MPS adoption behavior to sustain long-term usage behavior by appropriately understanding the context/situation which drives MPS adoption.
Stress and resilience to migrant entrepreneur-managers of small and medium enterprises during COVID-19 pandemic
Authors: Gautam Dhruba Kumar , Gautam Prakash Kumar 
Published: June 2023

PurposeThe purpose of the study is to investigate the stressors faced by migrant entrepreneur-managers of small and medium-sized enterprises (SMEs) during the COVID-19 pandemic, as well as their resilience strategies for reviving their businesses.Design/methodology/approachThis study employs a qualitative research design based on grounded theory. Semi-structured interview questionnaire was used for one-to-one interviews with 20 migrant entrepreneur-managers, representing ten different business sectors during the peak of the COVID-19 pandemic of 2020 and 2021. Interviews were transcribed, coded into open code, axial code and selective code to identify the major themes, and analysis was done into three levels to explore the stressors and initial strategies implemented to cope with the crisis. Trustworthiness of the findings was ensured by credibility, transferability, dependability and conformability, and reflexivity.FindingsThis study explored three types of stressors: finance-related stressors, supplies-related stressors and human resources-related stressors in migrant SME entrepreneur-managers during the COVID-19 pandemic. The study revealed the use of comprehensive supply chain strategies followed by migrant SME entrepreneur-managers to be resilient enough to cope with a crisis situation like the COVID-19 pandemic.Originality/valueThis study covers an under-researched area of research related to stressors and resilience strategies in migrant SME entrepreneur-managers during the pandemic situation. A large body of prior research contributes to employees' stress and coping behaviors, while this paper focuses on stressors in migrant entrepreneur-managers in the special context of pandemics and their strategies to be resilient during a crisis situation. Thus, the findings of this study contribute to SME entrepreneur-managers, policy makers and academicians so that a large number of migrant entrepreneurs can develop resilient strategies for crisis situations. Furthermore, this study contributes to the supply chain resilience literature and resource dependency theory.
Parameterized shape adaptive materials for sportswear
Authors: Beem Jennifer , Hannah Iain , Hosoi A.E. 
Published: June 2023

PurposeConventional sportswear design does not take into account body size changes that many individuals experience (e.g. through pregnancy, puberty, menstruation, etc.). This paper aims to detail both the construction of a novel wearable shape-adaptive composite and a new meso-scale material design method, which enables the optimal creation of these structures.Design/methodology/approachThis work reports the development of a predictive computational model and a corresponding design tool, including results of a tensile testing protocol to validate their outputs. A mathematical model was developed to explore the geometric parameter space of a bi-stable composite system, which then feeds into an optimization design tool.FindingsThe authors found that it is possible to fabricate shape-adaptive composites via 3D printing bi-stable structures, and adhering them to a base textile. Experimental mechanical tensile testing showed good agreement with the predictive model in mid-range unit cell amplitude designs. To illustrate how the optimization design tool works this paper details two design examples, one for expected shape change during pregnancy and one for targeted compression for high performance swimwear. The optimized design parameters are shown to replicate the target parameters, however there is potential for further improvement with a lower stiffness base textile.Originality/valueAlthough there is a wealth of research on multi-stable mechanisms, there is a dearth of studies that apply these structures in the wearable composite space. Additionally, there is a need for design methods which leverage the structurally-programmable capabilities of multi-stable structures to create optimized, high-performance functional composites.
Business model transformation: what is known and what is to be further developed?
Authors: Selezneva Aleksandra , Veselova Anna , Anand Amitabh 
Published: June 2023

PurposeThe paper presents a systematic literature review on business model transformation (BMT). The aim of the study is to determine the main research streams in BMT literature, develop a conceptual model on BMT research, and identify potential directions for future research.Design/methodology/approachThe authors use systematic literature review approach and provide a detailed protocol to meet reliability requirements. The study is based on the multilayer in-depth analysis of 92 articles published in leading international journal in general management, international business, strategy, innovation, and organization studies.FindingsThe paper identifies a crucial importance of further research on BMT with regards to the context specificity of a company's country of origin, transformation of value delivery and value capture blocks of BMs, entrepreneurial techniques of BMT management, and international aspects of BMT.Originality/valueBy a means of systematic literature review, the paper envisages the current state of knowledge about BMT, traces the development of BMT research, classifies it, and identifies potential directions for future inquiries.
Balancing structural IT capabilities for organizational agility in digital transformation: a resource orchestration view
Authors: Mao Hongyi , Liu Shan , Gong Yeming 
Published: June 2023

PurposeTo achieve digital transformation, organizations have continued to rely on integrating the capabilities of information technology (IT) to facilitate decision-making and developing their reconfiguration capability to enhance agile operations. The pressure imposed by digital transformation necessitates investigations on leveraging different IT capabilities to attain substantial organizational agility in an optimal configuration. This study aims to provide a new perspective on balancing IT structural capabilities and proposes a framework for evaluating their coalignment and complementary returns based on resource orchestration theory.Design/methodology/approachA multi-method approach is used to evaluate the research model. This study tests hypotheses and explores the potential coalignment and complementary returns of balance in structural models and response surface analysis. Then, it analyzes the qualitative data and provides complementary findings to corroborate and confirm complex relationships.FindingsBalanced structural IT capabilities facilitate organizational agility but cooperate differently with internal (e.g. IT proactive stance) and external (e.g. environmental volatility) environmental factors. Balance between IT integration and reconfiguration must be maintained from several approaches during search/selection and configuration/deployment.Originality/valueThis study theorizes and empirically investigates the interactive mechanisms of two IT capabilities in influencing organizational agility under different boundary conditions. It enriches the understanding of balancing capabilities for organizational agility in digital transformation.
I'd better say something! How empathy shapes bystander psychological reactance and intervention to online trolling of service organizations
Authors: Mulcahy Rory Francis , Riedel Aimee , Keating Byron W. , Beatson Amanda , Campbell Marilyn 
Published: June 2023

PurposeOnline trolling is a detrimental behavior for consumers and service businesses. Although online trolling research is steadily increasing, service research has yet to thoroughly explore how this behavior impacts businesses. Further, the role of bystanders, consumers who witness a victim (business) being trolled, remains largely unexplored. The purpose of this paper is thus to introduce online trolling to the service literature and begin to identify when (types of online troll content) and why (empathy and psychological reactance) bystanders are likely to intervene and support a service business being trolled by posting positive eWOM.Design/methodology/approachThis research uses a two-study (Study 1 n = 313; Study 2 n = 472) experimental design with scenarios of a service business experiencing online trolling (moral versus sadistic). Participants' responses as bystanders were collected via an online survey.FindingsResults reveal bystanders are more likely to post positive eWOM to support a service organization experiencing sadistic trolling. Psychological reactance is shown to mediate the relationship between trolling type and positive eWOM. Further, spotlight analysis demonstrates that bystanders with higher levels of empathy are more likely to post positive eWOM, whereas bystanders with low levels of empathy are likely to have a significantly higher level of psychological reactance.Originality/valueThis research is among the first in the service literature to specifically explore the consumer misbehavior of online trolling. Further, it provides new perspectives to online trolling by probing the role of bystanders and when and why they are likely to support service organizations being trolled.
Do non-local CEOs affect environmental, social and governance performance?
Authors: Huang Min , Li Mengyao , Li Xiaobo 
Published: June 2023

PurposeBuilding on the intergroup relations perspective on the social identity theory, the authors examine whether firms' environmental, social and governance (ESG) varies when local firms have non-local CEOs. Additionally, the authors examine which contextual factors may strengthen or weaken the effectiveness of ESG in helping non-local CEOs garner trust, legitimacy and resources support from local stakeholders.Design/methodology/approachPooled OLS regressions, based on unbalanced panel data and controlling for year and industry fixed effects, were estimated using a sample composed of 836 Chinese A-share listed firms that have Bloomberg ESG disclosure scores data from 2006 to 2019.FindingsResults suggest that companies with non-local CEOs, who are perceived as outgroup members by the local stakeholders, would lead to a higher level of ESG performance to overcome the intergroup bias they face. In addition, results also show that companies with a lower level of previous ESG decoupling and having more slack will mitigate the relationship between non-local CEOs and ESG performance. Conversely, firm visibility at a high level will promote the positive relationship between non-local CEOs and ESG performance.Originality/valueThis study offers theoretical insights that extend the focus of intragroup relation to outgroup identity, by introducing an intergroup relations lens to explore how outgroup (or nonprototypical) leaders utilize ESG to counter intergroup bias they suffer. Moreover, this study also extends current literature focusing on non-local CEOs and ESG performance.
Stalling or oiling the engines of diagnosis? Shifting perspectives on the DSM and categorical diagnosis in psychiatry
Authors: Pickersgill Martyn 
Published: June 2023

AbstractDiagnosis in psychiatry and its precursors has long attracted debate and dissent. Attempts to discipline professional praxis are associated especially with the American Psychiatric Association’s (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM). In this article, I explore how social actors with the institutional power to contribute in important ways to shaping psychiatric contexts construct the problems with and purposes of the DSM and of diagnosis in psychiatry. I suggest that despite common assumptions that influential psychiatrists and related stakeholders uncritically adopt the DSM and other tools of categorical diagnosis, their relationship with these is rather more nuanced, ambivalent, and even fraught. However, I will also show that critiques can themselves be folded into particular styles of psychiatric thought in ways that do little to impact wider concerns about biomedicalisation and pharmaceuticalisation—and might even further accelerate these processes. Moreover, since professional critiques of the DSM often underscore its ubiquity and entrenchment, when positioned against implicit or explicit justifications of the ongoing use of this text they might inadvertently contribute to a ‘discourse of inevitability’—acting to ‘oil’ rather than ‘stall’ what Annemarie Jutel terms the ‘engines of diagnosis’.
The copper resistance mechanism in a newly isolated Pseudoxanthomonas spadixZSY‐33
Authors: Wang Hongjie , Zhang Siyao , Zhang Jing 
Published: June 2023

AbstractResolving the heavy metal resistance mechanisms of microbes is crucial for understanding the bioremediation of the ecological environment. In this study, a multiple heavy metal resistance bacterium, Pseudoxanthomonas spadix ZSY‐33 was isolated and characterized. The copper resistance mechanism was revealed by analysis of the physiological traits, copper distribution, and genomic and transcriptomic data of strain ZSY‐33 cultured with different concentrations of copper. The growth inhibition assay in basic medium showed that the growth of strain ZSY‐33 was inhibited in the presence of 0.5 mM copper. The production of extracellular polymeric substances increased at a lower concentration of copper and decreased at a higher concentration of copper. Integrative analysis of genomic and transcriptomic, the copper resistance mechanism in strain ZSY‐33 was elucidated. At a lower concentration of copper, the Cus and Cop systems were responsible for the homeostasis of intracellular copper. As the concentration of copper increased, multiple metabolism pathways, including the metabolism of sulfur, amino acids, and pro‐energy were cooperated with the Cus and Cop systems to deal with copper stress. These results indicated a flexible copper resistance mechanism in strain ZSY‐33, which may acquire from the long‐term interaction with the living environment.
Transplantation of initially rejected donor lungs using ex vivo lung perfusion: A 5‐year experience
Authors: Graeser Karin , Blanche Paul F. , Zemtsovski Mikhail 
Published: June 2023

AbstractBackgroundEx vivo lung perfusion (EVLP) is a method for the evaluation and reconditioning of high‐risk donor lungs to increase the pool of potential donor lungs.MethodsWe reviewed all consecutive patients who received lung transplants from May 2012 to May 2017 with follow‐up until July 2021. EVLP was used in lungs initially rejected due to inadequate oxygenation but without other contraindications. Lungs with improved oxygenation levels above the threshold were transplanted. The primary endpoint was the time to graft failure, which was defined as the time from surgery to death or re‐transplantation, whichever occurred first. The secondary outcome was freedom from chronic lung allograft dysfunction.ResultsA total of 157 patients underwent transplantation during the study period. Thirty‐nine patients received EVLP‐treated donor lungs. Restricted mean graft survival time up to 7 years is 5.14 years for non‐EVLP and 4.19 for EVLP, the difference being −0.95 (confidence interval [CI]—1.93 to 0.04, p = .059). The hazard ratio is 1.66 (CI 1.00–2.75, p = .046). Chronic lung allograft dysfunction was the highest contributor to mortality in both groups. There were significant differences in freedom from chronic lung allograft dysfunction at 12 and 24 months of follow‐up (p = .005 and p = .030, respectively). Subgroup analyses revealed that the first patients who received EVLP in 2012–2013 had a substantially worse 5‐year graft survival than those who received EVLP more recently in 2016–2017 (14.3% vs. 60.0%). For the latter, the 5‐year graft survival was observed to be remarkably close to the non‐EVLP group (60.8%).ConclusionLong‐term survival was significantly lower, and lung function was poorer among recipients in the EVLP group than in the non‐EVLP group. However, the outcome of patients who received EVLP‐treated lungs was observed to improve steadily after the first 2 years after EVLP was introduced in Denmark.
Intermediate filament proteins are reliable immunohistological biomarkers to help diagnose multiple tissue‐specific diseases
Authors: Doganyigit Zuleyha , Eroglu Ece , Okan Aslı 
Published: June 2023

AbstractCytoskeletal networks are proteins that effectively maintain cell integrity and provide mechanical support to cells by actively transmitting mechanical signals. Intermediate filaments, which are from the cytoskeleton family and are 10 nanometres in diameter, are unlike actin and microtubules, which are highly dynamic cytoskeletal elements. Intermediate filaments are flexible at low strain, harden at high strain and resist breaking. For this reason, these filaments fulfil structural functions by providing mechanical support to the cells through their different strain‐hardening properties. Intermediate filaments are suitable in that cells both cope with mechanical forces and modulate signal transmission. These filaments are composed of fibrous proteins that exhibit a central α‐helical rod domain with a conserved substructure. Intermediate filament proteins are divided into six groups. Type I and type II include acidic and basic keratins, type III, vimentin, desmin, peripheralin and glial fibrillary acidic protein (GFAP), respectively. Type IV intermediate filament group includes neurofilament proteins and a fourth neurofilament subunit, α‐internexin proteins. Type V consists of lamins located in the nucleus, and the type VI group consists of lens‐specific intermediate filaments, CP49/phakinin and filen. Intermediate filament proteins show specific immunoreactivity in differentiating cells and mature cells of various types. Various carcinomas such as colorectal, urothelial and ovarian, diseases such as chronic pancreatitis, cirrhosis, hepatitis and cataract have been associated with intermediate filaments. Accordingly, this section reviews available immunohistochemical antibodies to intermediate filament proteins. Identification of intermediate filament proteins by methodological methods may contribute to the understanding of complex diseases.
Morphology of the syrinx of three species of birds from Brazilian cerrado (Psittacara leucophthalmus, Rhynchotus rufescens and Cariama cristata): Gross anatomy and light microscopy study
Authors: Oliveira Elton Luis Ritir , Zuliani Fernanda , de Camargo Gabriel Corrêa , Desantis Salvatore , Schimming Bruno Cesar 
Published: June 2023

AbstractThe aim of this study was to describe the morphology of the trachea and syrinx at macroscopic and light microscopy levels of three species of birds from different orders that inhabit the Brazilian cerrado. For that, five adult specimens (three males and two females of each species) of white‐eyed parakeet (Psittacara leucophthalmus), red‐winged tinamou (Rhynchotus rufescens) and red‐legged seriema (Cariama cristata) were used. The trachea and syrinx of the birds were collected and destined for anatomical and histological studies. The trachea of the studied birds presented an elongated path and originated in the larynx and extended caudally to the syrinx. No sexual dimorphism was observed in the syrinx of the studied species, probably because it is associated with their song, which is very similar between males and females of these species. The findings of this study allowed us to classify the syrinx as tracheal in the white‐eyed parakeet and tracheobronchial in the red‐winged tinamou and red‐legged seriema. In general, the morphological features of the trachea and syrinx were similar to those described for other species of birds, such as the presence of intrinsic and extrinsic syringeal muscles, and the lateral and medial tympaniform membranes, which would represent important anatomical structures in sound production through vibration during expiration and eventual inspiration. The morphological structure of the syrinx in the three avian species of the Brazilian cerrado is consistent with the ability of these avian species to perform a potential vocalization, especially the red‐legged seriema that emits characteristic sounds very loud and can carry several kilometres.