bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible neural color compatibility model for efficient color extraction from image
Authors: Yan Simin , Xu Shuchang , Zhang Sanyuan 
Published: August 2023

AbstractColor choice is an essential aspect of many applications, including graphic design, web design and fashion design. The selection of colors can have a significant impact on the overall aesthetic and appeal of a design, as well as its effectiveness in conveying a particular message or mood. This paper introduces new and simple tools for choosing colors. First, we introduce a convolutional neural network that scores the quality of a set of five colors, called a color theme. Such a network can be used to rate the quality of a new color theme. Second, we propose a method to extract a variable‐size palette from an image. The size of the extracted palette can vary depending on the color richness of the image. Third, we demonstrate simple prototypes that apply the trained neural network and the palette extraction method to tasks in graphic design, such as improving existing themes. Our proposed network has the advantage of being significantly simpler than other state‐of‐the‐art methods with better performance.
Cyclopentadienyl Molybdenum(II) Compounds Bearing Ether and Thioether Functions in the Side Chain: Synthesis, Characterization, and Cytotoxic/Cytostatic Studies
Authors: Hanzl Lukáš , Vinklárek Jaromír , Honzíček Jan , Dostál Libor , Císařová Ivana , Šacherlová Lucie , Eisner Aleš , Muthná Darina , Řezáčová Martina 
Published: August 2023

AbstractA series of molybdenum(II) compounds [(η5‐Cp’)Mo(CO)2(L2)][BF4] (Cp’=C5H4(CH2)2SPh, C9H6(CH2)2OMe, L2=N,N‐chelating ligand) have been synthesized and characterized by spectroscopic and analytical methods including X‐ray crystallography. The in vitro assay on human leukemia cells MOLT‐4 has shown that the substitution in the π‐ligand in combination with suitable N,N‐chelating ligand can lead to species with cytotoxicity considerably higher than reported to cisplatin. Unusually high activity was observed for compounds bearing phenanthroline ligands [{η5‐C9H6(CH2)2OMe}Mo(CO)2(3,4,7,8‐Me4phen)][BF4] (IC50=0.7±0.3 μM) and [{η5‐C9H6(CH2)2OMe}Mo(CO)2(4,7‐Ph2phen)][BF4] (IC50 values 0.8±0.4 μM).
Can unexploited biomass of Ficus carica L. be valorized as a bio‐based material for the development of functional food formulations?
Authors: Manousi Natalia , Mikroulis Theodoros , Mourtzinos Ioannis 
Published: August 2023

AbstractFigs are a valuable source of nutrients including polyphenols, dietary fiber, and minerals. Cultivation and consumption of figs generates a considerable amount of by‐products and waste which are also nutrient‐rich. Fig unexploited mass can efficiently be valorized in the frame of circular bioeconomy for the development of functional foods, food supplements, cosmetics, and pharmaceuticals. Herein, we provide a thorough assessment of the chemical composition of figs toward the potential utilization of unexploited fig biomass for the generation of bio‐based materials. Conventional and novel processes such as drying and extraction leading to the isolation of targeted ingredients are critically discussed.
Determination of total flavonoids, phenolics, and antioxidant activity of propolis from six stingless bee species in Kenya
Authors: Kegode Timothy M. , Ndungu Nelly , Kiatoko Nkoba 
Published: August 2023

AbstractBackgroundPropolis is one of the hive products made by bees from wax and plant resins, which makes it rich in phytochemicals such as flavonoids and phenolic. The chemical composition of propolis from stingless bees is affected by several factors including vegetation type and species. In Kenya, we have diverse landscape vegetation and over 12 stingless bee species. Lifestyle diseases are affecting more people due to unhealthy diets and exposure to harmful chemicals, which lead to oxidation in cells. This led to the production of super radicals, which cannot be neutralized only by the endogenous antioxidants in the body. This has led to increased demand for exogenous antioxidants obtained from the diet. Propolis is a known source of natural antioxidants too due to the presence of polyphenols.ResultsIn our study, we determined the total content of flavonoids, phenolic, and the antioxidant activity of propolis from six stingless bee species from Kenya. The total flavonoid content (TFC) in all species ranged from 651.90 to 3262.26 mg QE/100 g, while the total phenolic content (TPC) ranged from 586.36 to 2010.53 mg GAE/100 g. Among the species, Meliponula beccarii had the highest concentration of total flavonoids, Meliponula togoensis had high concentrations of total phenolic, while Meliponula ferruginea had the highest antioxidant activity.ConclusionThe outcome of this study demonstrates that propolis from Kenyan stingless bees have varying amounts of phytochemicals, which is dependent on the species identity. Hence it is a good source of exogenous natural antioxidants.
Edge Enhancement Optimization in Flexible Endoscopic Images to the Perception of Ear, Nose and Throat Professionals
Authors: Geleijnse G. , Veder L. L. , Hakkesteegt M. M. , de Gier H. H. W. , Rieger B. , Metselaar R. M. 
Published: August 2023

ObjectivesDigital endoscopes are connected to a video processor that applies various operations to process the image. One of those operations is edge enhancement that sharpens the image. The purpose of this study was to (1) quantify the level of edge enhancement, (2) measure the effect on sharpness and image noise, and (3) study the influence of edge enhancement on image quality perceived by ENT professionals.MethodsThree digital flexible endoscopic systems were included. The level of edge enhancement and the influence on sharpness and noise were measured in vitro, while systematically varying the levels of edge enhancement. In vivo images were captured at identical levels of one healthy larynx. Each series of in vivo images was presented to 39 ENT professionals according to a forced pairwise comparison test, to select the image with the best image quality for diagnostic purposes. The numbers of votes were converted to a psychometric scale of just noticeable differences (JND) according to the Thurstone V model.ResultsThe maximum level of edge enhancement varied per endoscopic system and ranged from 0.8 to 1.2. Edge enhancement increased sharpness and noise. Images with edge enhancement were unanimously preferred to images without edge enhancement. The quality difference with respect to zero edge enhancement reaches an optimum at levels between 0.7 and 0.9.ConclusionEdge enhancement has a major impact on sharpness, noise, and the resulting perceived image quality. We conclude that ENT professionals benefit from this video processing and should verify if their equipment is optimally configured.Level of EvidenceNA Laryngoscope, 134:842–847, 2024
Fabrication and Characterization of an Electro‐Compacted Collagen/Elastin/Hyaluronic Acid Sheet as a Potential Skin Scaffold
Authors: Kang Lingzhi , Zhou Ying , Chen Xifang , Yue Zhilian , Liu Xiao , Baker Chris , Wallace Gordon G. 
Published: August 2023

AbstractThe development of biomimetic structures with integrated extracellular matrix (ECM) components represents a promising approach to biomaterial fabrication. Here, an artificial ECM, comprising the structural protein collagen I and elastin (ELN), as well as the glycosaminoglycan hyaluronan (HA), is reported. Specifically, collagen and ELN are electrochemically aligned to mimic the compositional characteristics of the dermal matrix. HA is incorporated into the electro‐compacted collagen‐ELN matrices via adsorption and chemical immobilization, to give a final composition of collagen/ELN/HA of 7:2:1. This produces a final collagen/ELN/hyaluronic acid scaffold (CEH) that recapitulates the compositional feature of the native skin ECM. This study analyzes the effect of CEH composition on the cultivation of human dermal fibroblast cells (HDFs) and immortalized human keratinocytes (HaCaTs). It is shown that the CEH scaffold supports dermal regeneration by promoting HDFs proliferation, ECM deposition, and differentiation into myofibroblasts. The CEH scaffolds are also shown to support epidermis growth by supporting HaCaTs proliferation, differentiation, and stratification. A double‐layered epidermal‐dermal structure is constructed on the CEH scaffold, further demonstrating its ability in supporting skin cell function and skin regeneration.
The optimal decision for automobile enterprises considering shareholding strategies and dual‐credit policy
Authors: Pu Junchong 
Published: August 2023

AbstractThis article develops a new energy vehicle (NEV) supply chain comprising a manufacturer and a retailer, considers the incentive effect of the dual‐credit policy, proposes three shareholding strategies (manufacturer shareholding, retailer shareholding, and cross‐shareholding), and investigates the optimal decisions of NEV enterprises. Our results indicate that increased credit trading price, manufacturer shareholding ratio, and retailer shareholding ratio all improve NEV low‐carbon levels and manufacturer profits. In contrast, the performance of retailer profits is more complex and requires a lower range of shareholding ratio in most situations to achieve growth. Meanwhile, the cross‐shareholding strategy is the optimal choice for the manufacturer. However, the retailer only sometimes benefits from a cross‐shareholding strategy, and the manufacturer shareholding strategy can lead to the highest retailer profits in most cases. Furthermore, these findings can provide critical managerial insights for automobile enterprises and governments.
A multi‐tier computational screening framework to effectively search the mutational space of SARS‐CoV‐2 receptor binding motif to identify mutants with enhanced ACE2 binding abilities
Authors: Chakraborty Sandipan , Saha Chiranjeet 
Published: August 2023

AbstractSARS‐CoV‐2 gained crucial mutations at the receptor binding domain (RBD) that often changed the course of the pandemic leading to new waves with increased case fatality. Variants are observed with enhanced transmission and immune invasion abilities. Thus, predicting future variants with enhanced transmission ability is a problem of utmost research interest. Here, we have developed a multi‐tier exhaustive SARS‐CoV‐2 mutation screening platform combining MM/GBSA, extensive molecular dynamics simulations, and steered molecular dynamics to identify RBD mutants with enhanced ACE2 binding capability. We have identified four RBM mutations (F490K, S494K, G504F, and the P499L) with significantly higher ACE2 binding abilities than wild‐type RBD. Compared to wild‐type RBD, they all form stable complexes with more hydrogen bonds and salt‐bridge interactions with ACE2. Our simulation data suggest that these mutations allosterically alter the packing of the RBM interface of the RBD‐ACE2 complex. As a result, the rupture force required to break the RBD‐ACE2 contacts is significantly higher for these mutants.
Stress appraisal and emotion regulation mediate the association between mindfulness and affect in cancer patients: Differential mechanisms for positive and negative affect
Authors: Tungtong Puttichai , Ranchor Adelita V. , Schroevers Maya J. 
Published: August 2023

AbstractObjectiveCancer patients are at an increased risk for affective problems, including feelings of anxiety and depression. Mindfulness has been linked to an array of benefits for affective functioning in various populations including cancer patients, but the mechanisms underlying this relationship are still poorly understood. Based on emotion‐regulation and stress‐coping models, this study examined the potential mediating role of stress appraisal and coping strategies in the associations between mindfulness and cancer patients' positive and negative affect.MethodsFor this cross‐sectional study, 245 cancer patients completed self‐report questionnaires measuring mindfulness (FFMQ), positive and negative affect (PANAS), stress appraisal (SPSI‐R:S), coping through positive reappraisal and positive refocusing (CERQ), rumination (RRQ), and distraction (COPE). Serial mediation analyses were conducted using the regression‐based bootstrapping method.ResultsHigher levels of mindfulness were associated with higher levels of positive affect; this relationship was mediated via stress appraisal and positive reappraisal. We also found an indirect effect from mindfulness directly via positive reappraisal to positive affect. In addition, higher levels of mindfulness were negatively associated with negative affect; this relationship was mediated via stress appraisal and rumination, with also an indirect effect from mindfulness directly via stress appraisal to negative affect.ConclusionsResults suggest that stress appraisal and distinct coping strategies mediate the relationship between mindfulness and affect. Mindfulness may provide benefits for cancer patients' affect by allowing adaptive stress appraisal and ways of coping through more positive and less negative thinking.
On Western and Eastern Media Systems: Continuities and Discontinuities
Authors: Miconi Andrea , Papathanassopoulos Stylianos 
Published: August 2023

AbstractThis chapter aims to discuss the relevant literature related to Mancini and Hallin’s comparative media systems model, taking into account the case of the Eastern European media as well. It is tried to draw the main features of the so-called post-Socialist media markets. After a brief discussion on how media systems change across time and vary across space, the chapter explores to what extent we can add a “post-communist” cluster to the initial Hallin and Mancini’s classification. It is assumed that the post-Socialist transition has deeply changed the social and economic tissue of all ex-Eastern European countries. As the case of media in Eastern Europe reveals even in countries with a shared social political past, there is still ground for specificities to be flourished that eventually will lead to different paths of media market development. It is argued that even if we witness the triumph of certain general tendencies of what is described as the consolidation of media market globalization, this process could not be understood in its full potentials, without taking into consideration how the political, cultural, and economic “legacy” of each European member state.
MRI‐based torsion measurement of the lower limb is a reliable and valid alternative for CT measurement: a prospective study
Authors: Grünwald Leonard , Histing Tina , Springer Fabian , Keller Gabriel 
Published: August 2023

AbstractPurposeThe aim of this study was to compare MRI‐based torsion measurements of the lower limb to a well‐established CT‐based assessment in a prospective inter‐ and intraindividual approach.MethodsA total of 26 patients (age 28.8 years ± 11.0) were enrolled beginning in January 2021 until August 2022. Inclusion criteria were the clinical indication for torsion measurement of the lower limb. CT and MRI imaging were performed with a standard operating procedure, to ensure that all patients were examined in a standardized position. The examinations were planned on a coronal scout view based on prominent anatomical landmarks. Femoral and tibial torsion were measured individually. Torsion measurements were analysed twice: immediately after examination and after 3 weeks. Subsequently, intra‐rater and parallel test reliability was calculated accordingly.ResultsHigh significant results for CT and MRI measurements for both tibia (MRI: r = 0.961; p ≤ 0.001; CT: r = 0.963; p ≤ 0.001) and femur (MRI: r = 0.980; p ≤ 0.001; CT: r = 0.979; p ≤ 0.001) were obtained by calculated intra‐rater reliability, showing that measurements were highly consistent for MRI and CT, respectively. Parallel test reliability for time point 1 as well as time point 2 was also highly significant and ranged from r = 0.947 to r = 0.972 (all with p ≤ 0.001, respectively) for both tibia and femur, showing a high concordance between the two measurements.ConclusionMeasurement of tibial as well as femoral torsion was comparable for CT and MRI measurement. Therefore, this study supports MRI measurement as an equivalent alternative for CT measurement concerning torsional malalignment to reduce exposure to radiation.Level of evidenceLevel II.
Untersuchung eines Doppelspitzschlägels aus dem Umfeld der römischen Siedlung Michlhallberg nahe Altaussee (Steiermark, Österreich)
Authors: Modl Daniel , Strobl Susanne , Haubner Roland 
Published: August 2023

ZusammenfassungEin eiserner Doppelspitzschlägel aus dem Umfeld der römischen Siedlung am Michlhallberg (Steiermark) wurde untersucht, der im Kontext mit einem möglichen römischen Salzabbau an der Südseite des Sandlings bei Altaussee steht. Das Eisen für den Doppelspitzschlägel wurde aus einer Rennfeuerluppe hergestellt. Durch diese Art der Eisengewinnung ist eine Weiterverarbeitung durch Schmieden notwendig. So findet man im Schlägel sowohl Schlacke als auch eine recht ungleichmäßige Kohlenstoffverteilung. Deshalb erfolgte eine Probenentnahme an mehreren Stellen.Es liegt ein variationsreiches Stahlgefüge vor, bestehend aus unter-, über- und eutektoidem Kohlenstoffgehalt. Von beinahe reinem polygonalem Ferrit über Widmannstättschem, Korngrenzen- und säulenartigem Ferrit treten auch Perlit (unterschiedlicher Feinheit), Zwischenstufe (Bainit), Martensit, sowohl tetragonaler als auch kubischer, und reiner Zementit, langnadelig bzw. an den Korngrenzen, auf.Es wurde auch die abgebrochene Spitze eines Doppelspitzschlägels untersucht, die möglicherweise mit der Reparatur eines defekten Schlägels zusammenhängt. Regelmäßige Reparaturen an den Gezähen waren notwendig.
Development of a tetra-primer ARMS–PCR for identification of sika and red deer and their hybrids
Authors: Ke-xin Yu , Xiang Chen , Qing-qing Hu , Yi-an Yao , Xiao-ming Wang , Ai-chun Xu , Jian Ge , Feng Guan 
Published: August 2023

AbstractAccurate identification of deer-derived components is significant in food and drug authenticity. Over the years, several methods have been developed to authenticate these products; however, identifying whether female deer products are hybrids is challenging. In this study, the zinc finger protein X-linked (ZFX) gene sequences of sika deer (Cervus nippon), red deer (Cervus elaphus) and their hybrid offspring were amplified and sequenced, the X221 and X428 species-specific single nucleotide polymorphisms (SNP) loci were verified, and a tetra-primer amplification refractory mutation system (T-ARMS–PCR) assay was developed to identify the parent-of-origin of female sika deer, red deer, and their hybrid deer. The T-ARMS–PCR developed based on the X221 locus could identify sika deer, red deer, and their hybrid offspring according to the presence or absence of PCR product sizes of 486 bp, 352 bp, and 179 bp, respectively, just as X428 locus could identify sika deer, red deer, and their hybrid offspring according to the presence or absence of PCR product sizes of 549 bp, 213 bp, and 383 bp, respectively. Forty products labeled deer-derived ingredients randomly purchased were tested using this assay, and the results showed that the identification results based on the two SNP loci were utterly consistent with the actual sources. In addition, this method was found to be accurate, simple, convenient, and with high specificity, thus providing an essential technical reference for deer product species identification. It is also an important supplement to the identification methods of the original ingredients of existing deer products.
Graphical abstract
Impacts of tidewater glacier advance on iceberg habitat
Authors: Kaluzienski Lynn M. , Amundson Jason M. , Womble Jamie M. , Bliss Andrew K. , Pearson Linnea E. 
Published: August 2023

AbstractIcebergs in proglacial fjords serve as pupping, resting and molting habitat for some of the largest seasonal aggregations of harbor seals (Phoca vitulina richardii) in Alaska. One of the largest aggregations in Southeast Alaska occurs in Johns Hopkins Inlet, Glacier Bay National Park, where up to 2000 seals use icebergs produced by Johns Hopkins Glacier. Like other advancing tidewater glaciers, the advance of Johns Hopkins Glacier over the past century has been facilitated by the growth and continual redistribution of a submarine end moraine, which has limited mass losses from iceberg calving and submarine melting and enabled glacier thickening by providing flow resistance. A 15-year record of aerial surveys reveals (i) a decline in iceberg concentrations concurrent with moraine growth and (ii) that the iceberg size distributions can be approximated as power law distributions, with relatively little variability and no clear trends in the power law exponent despite large changes in ice fluxes over seasonal and interannual timescales. Together, these observations suggest that sustained tidewater glacier advance should typically be associated with reductions in the number of large, habitable icebergs, which may have implications for harbor seals relying on iceberg habitat for critical life-history events.
Creeping up on the Roman Provincial
Authors: Wiedemann Ben 
Published: August 2023

AbstractAround the year 1200, the court of the Roman pope produced a list of all the bishops – and hence of all the cities – in the Christian world. For the next three centuries this text was copied and updated by kings, priests, lawyers and academics across Europe. The numerous surviving manuscripts of this text – the so–called ‘Roman provincial’ – have received some attention from scholars, but the sheer number of manuscripts has meant that any attempt to catalogue and study them en masse is all but destined to fail. This article suggests a different approach: that the most interesting feature of the provincial manuscripts is their differences; the ways in which copyists changed the ecclesiastical and political geography of Europe to meet their own preferences and expectations. Political geographers and modern historians have long been aware of ‘contested cartographies’ and battles over borders on maps; by studying the Roman provincial we can apply such lenses to the medieval world too. Thirteenth-century kings were quite as aware as we are that maps and lists constitute, rather than just describe, political realities.
Digital Platform Employment in Kazakhstan: Can New Technologies Solve Old Problems in the Labor Market?
Authors: Insebayeva Sabina , Beyssembayev Serik 
Published: August 2023

AbstractRecent years have witnessed an upsurge of interest in the “sharing,” “gig,” or “on-demand” economy, which has been changing the relationships between customers, workers, and companies. While literature on the gig economy in the Western context abounds, few studies have focused on “digitalized” labor relations in the Central Asian context.Drawing on qualitative field research in Kazakhstan in 2016 and 2021, supplemented by quantitative data, this article contributes to debates about labor relations and the digitalized “gig” economy in a non-Western context. It provides a novel, in-depth, multisource account of the structure of platform-based business and work experiences in the digitally enabled Kazakh gig economy. Using ethnographic evidence, we offer a detailed analysis of labor conditions from the perspective of platform-based companies and gig workers, identifying resistance and “survival” strategies used to navigate and even challenge the existing system characterized by “algorithmic management” or “algorithm-based” labor relations.