bluuebunny/crossref_metadata_2025_split huggingface dataset:
BALANÇO AMBIENTAL SKINNERIANO: REFORÇO E PUNIÇÃO COMO GANHOS E PERDAS E REGISTRO DIGITAL
Authors: Cavagnari Daniel Weigert , Antiqueira Lia Maris Orth Ritter 
Published: September 2023

Este estudo teve como objetivo estabelecer valores e referências, pelo método de observação indutiva, com base nas ações humanas em relação ao meio ambiente, assim como da natureza em relação aos diversos tipos de ambientes. O propósito foi criar uma base para futuros registros ambientais digitais eficazes e sensíveis, com tecnologia apropriada, que considerem a perspectiva humana ou da natureza. Para essa definição lógica, utilizando a teoria comportamental skinneriana, foram considerados os conceitos de reforço e punição positivos e negativos, para explorar diversas ocorrências e suas consequências socioambientais. Por se tratar de uma teoria baseada em ações antropogênicas e ocorrências naturais, que repercutem na sociedade e no meio ambiente, causando ganhos e perdas, aprendizados e traumas, consideramos as características particulares de cada agente, humano e natureza, sem rotulagens, números singulares, abstrações generalizadas ou atribuições antropomórficas. Dessa forma, chegamos ao que chamamos de "ganhos e perdas skinnerianos" (GPs), que estabelecem valores e simbologias que podem ser registrados, definindo um equilíbrio ambiental com até dezesseis atribuições, quatro para cada agente responsável em relação ao afetado, ou seja, humano ou natureza, para o meio ambiente ou sociedade.
Palavras-chave: natureza; sociedade; meio ambiente; sustentabilidade; educação ambiental.

Skinnerian environmental balance: reinforcement and punishment as gains and losses and digital record

ABSTRACT: This study aimed to establish values and references through the method of inductive observation, based on human actions in relation to the environment, as well as nature's interactions within various types of environments. The purpose was to create a foundation for future effective and sensitive digital environmental records, utilizing appropriate technology, that considers the human or natural perspective. For this logical definition, employing the Skinnerian behavioral theory, concepts of positive and negative reinforcement and punishment were considered to explore various occurrences and their socio-environmental consequences. As this theory is rooted in anthropogenic actions and natural events, impacting society and the environment, causing gains and losses, learning, and traumas, the particular characteristics of each agent, human and nature, were considered without labels, singular numbers, generalized abstractions, or anthropomorphic attributions. In this manner, we arrived at what we refer to as "Skinnerian gains and losses" (GPs), which establish values and symbolisms that can be recorded, defining an environmental balance with up to sixteen attributions, four for each responsible agent in relation to the affected, namely, human or nature, environment, or society.
Keywords: nature; society; environment; sustainability; environmental education.
Analisis sentimen masyarakat terhadap informasi penerapan PPN atas renovasi dan membangun rumah sendiri pada media sosial youtube dengan metode svm dan naive bayes
Authors: Kusuma Muhammad Romadhona , Gata Windu , Kurniawati Laela , Rivan Almay Faiz , Kurniawan Triadi 
Published: September 2023

Penelitian ini dilakukan untuk menganalisis komentar masyarakat terhadap informasi penerapan pajak pertambahan nilai atas kegiatan renovasi dan membangun rumah sendiri yang kini telah diumumkan oleh pemerintah melalui kementrian keuangan. Analisis ini dilakukan untuk mengetahui bagaimana pandangan masyarakat terhadap adanya informasi tersebut dengan memfokuskan pada gaya bahasa yang digunakan masyarakat dalam menyampaikan komentarnya serta maksud dari komentar yang disampaikan atau ditulis. Karena tidak mudah untuk menganalisis sentimen dari berbagai komentar, hal ini karena komentar mengandung teks yang tidak terstruktur, terutama dalam teks Indonesia. Prapemrosesan teks dalam penambangan teks merupakan bagian penting untuk mendapatkan informasi dasar yang terkandung dalam komentar. Adapun penelitian yang dilakukan menggunakan pra-pemrosesan teks Indonesia dengan Textmining menggunakan rapid minner. Teknik pengumpulan data dilakukan melalui pengumpulan komentar di media sosial youtube kanal berita viva.co.id dari tanggal 10 april 2022 hingga 30 juni 2022 dengan jumlah 1650 komentar . Kemudian dilanjutkan dengan mengekstraksi informasi menggunakan metode klasifikasi Naïve Bayes dan Support Vector Machine yang dioptimalkan menggunakan Particle Swarm Optimization. Hasil penelitian ini menunjukkan bahwa komentar masyarakat mengenai informasi penerapan pajak pertambahan nilai atas kegiatan renovasi dan membangun rumah sendiri beraneka ragam. Ada yang setuju, ada yang tidak setuju, dan ada pula yang tidak tahu menahu. Simpulan dari penelitian ini hendaknya pemerintah melalui kementerian keuangan RI memberikan sosialisasi yang luas kepada masyarakat, agar masyarakat tidak bingung terhadap informasi tersebut sehingga masyarakat tidak akan asal berkomentar dengan pendapatnya masing-masing.
Analisis kejahatan phising pada sektor e-commerce di marketplace shopee
Authors: Puspitasari Devi , Sutabri Tata 
Published: September 2023

Cybercrime merupakan kejahatan yang dilakukan dengan menggunakan teknologi komputer sebagai kejahatan utama. Kejahatan yang terjadi di zaman modern ini semakin berkembang dan berbagai kejahatan yang terjadi saat ini juga telah masuk ke dunia maya dalam bentuk kejahatan phising. Kejahatan phising adalah ancaman yang menggunakan teknik manipulatif dan menipu pengguna dengan menyamar sebagai orang yang berwenang, vendor atau peserta e-commerce untuk mendapatkan informasi sensitif pengguna. Penelitian ini membahas tentang faktor penyebab phising dan mencegah ancaman serangan phising yang terjadi pada sektor e-commerce. Metode yang digunakan adalah metode literature review. Faktor penyebab phising adalah minimnya pengetahuan pengguna, penambangan data pengguna, menarik pengguna dengan hadiah, dan sebagainya. Meskipun pencegahan dapat dicapai dengan mengedukasi pengguna, hal ini dapat menghindari ancaman kejahatan phising di email,URL atau situs web dan lain-lain.
Applying Heterogeneous Catalytic Reactions for Organic Chemical Syntheses
Authors: Hegedűs László , Hell Zoltán 
Published: September 2023

In this review the most important results achieved in the recent 12–15 years are summarized focusing on the heterogenous catalytic hydrogenations over transition metals (Pd, Pt, Ru, Rh, La), as well as the application of palladium, copper and other metals on a molecular sieve (4A) support in several organic chemical syntheses in liquid phase.
Osteoarthritis disease progression through the lower extremity: A review
Authors: Canton David , Conte Michael , Kammen Pamela 
Published: September 2023

It has long been felt that osteoarthritis is the result of wear and tear. Many physicians are not aware that biological science has now validated that this increased “wear and tear” on the joint is the result of loading-induced stresses that undermine cell function and aging. The loading creates shear forces on the cartilage that leads to increased oxidants. These oxidants then cause chondrocyte premature aging, leading to the development of what we know as osteoarthritis.
Studies have also found a significant association between foot pain and knee and hip pain. Likewise, many physicians are not aware of the relationship between the hip, knee and foot are a result of the kinetic chain. The kinetic chain being the dynamic transfer of forces during ambulation of the foot, ankle, knee, and hip. The kinetic chain explains how the body’s joints and segments affect one another during movement, and so play a role in pain. The pain results from transferred mechanical stress from one joint to another. The same stress and shear forces that leads to osteoarthritis.
This article involves a literature of the connection of osteoarthritis and the kinetic chain in the lower limb and highlights the need to consider related joints in the kinetic chain when addressing and injury in one joint to address and perhaps delay progression of osteoarthritis in related joints.
Pembinaan Keterampilan Mahasiswa dalam Promosi Kesehatan Melalui Pemanfaatan Aplikasi Monitor Kebugaran Pacer Health
Authors: Laeto Arwan Bin 
Published: September 2023

Peningkatan penyakit infeksi dan non infeksi yang masih tinggi di Indonesia menjadi penting dilakukan edukasi kesehatan kepada masyarakat. Mahasiswa sebagai kelompok yang memiliki tanggungjawab mengembangkan kompetensi perlu menguasai perkembangan teknologi dan keterampilan komunikasi efektif. Kegiatan ini bertujuan untuk membina keterampilan mahasiswa dalam melakukan promosi kesehatan melalui pemanfaatan teknologi aplikasi Pacer Health guna monitor kebugaran tubuh. Metode dalam kegiatan pengabdian ini adalah pelatihan dengan kelompok sasaran yaitu mahasiswa baru Fakultas Kedokteran Universitas Sriwijaya. Tahapan kegiatan meliputi edukasi yang disertai kuis sebelum dan sesudah edukasi, diskusi kelompok mahasiswa dan demonstrasi promosi kesehatan melalui pemanfaatan aplikasi Pacer Health guna memonitor kebugaran tubuh. Hasil yang diperoleh dari kegiatan pengabdian ini adalah terjadi peningkatan pengetahuan mahasiswa terkait kesehatan olahraga sebanyak 57,8%, teknologi kedokteran meningkat sebanyak 64,9%, aplikasi Pacer Health sebanyak 63,5% dan teknik promosi kesehatan sebanyak 58,7%. Mahasiswa juga mengalami peningkatan keterampilan dalam penggunaan aplikasi kesehatan dan terjadi penambahan pengalaman dalam menyusun strategi dan pelaksanaan promosi kesehatan, khususnya melalui pemanfaatan teknologi sekaligus dapat meningkatkan kompetensi komunikasi efektif. Pasca kegiatan ini, mahasiswa disarankan untuk terus mendalami perkembangan teknologi aplikasi kesehatan yang dapat membantu dalam menjalankan profesi sebagai dokter kelak.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI MINAT MAHASISWA AKUNTANSI DALAM PEMILIHAN KARIR SEBAGAI AKUNTAN PUBLIK
Authors: Andika Bagus , L. Tobing Vargo Christian 
Published: September 2023

ABSTRACT
This study aims to to determine the factors that influence the interest of accounting students in choosing a career as a public accountant. The data analysis method used in this study consisted of descriptive statistical tests, data quality tests, consisting of validity and reliability tests, classical assumption tests, multiple linear regression tests, coefficient of determination tests, and hypothesis testing consisting of t tests and f tests. The results of testing the hypothesis in this study indicate that partially financial rewards, job market considerations, and professional training have a positive and significant effect on the interest of accounting students in choosing to become public accountants, and simultaneously financial rewards, job market considerations, and professional training have a positive effect and significant to the interest of accounting students in choosing a career as a public accountant. The test results for the coefficient of determination in this study were 0.551, so the independent variables in this study had an influence on the dependent variable of 55.1%, the remaining 44.9% were influenced by other variables outside this study.
Keywords: financial rewards, job market consideration, professional training, students interest
Exploring atherosclerosis imaging with contrast-enhanced MRI using PEGylated ultrasmall iron oxide nanoparticles
Authors: Zhang Ruru , Lu Kuan , Xiao Li , Hu Xuelan , Cai Wu , Liu Linjiang , Liu Yan , Li Weihua , Zhou Hui , Qian Zhiyuan , Wang Sixia , Chen Can , Zeng Jianfeng , Gao Mingyuan 
Published: September 2023

Plaque rupture is a critical concern due to its potential for severe outcomes such as cerebral infarction and myocardial infarction, underscoring the urgency of noninvasive early diagnosis. Magnetic resonance imaging (MRI) has gained prominence in plaque imaging, leveraging its noninvasiveness, high spatial resolution, and lack of ionizing radiation. Ultrasmall iron oxides, when modified with polyethylene glycol, exhibit prolonged blood circulation and passive targeting toward plaque sites, rendering them conducive for MRI. In this study, we synthesized ultrasmall iron oxide nanoparticles of approximately 3 nm via high-temperature thermal decomposition. Subsequent surface modification facilitated the creation of a dual-modality magnetic resonance/fluorescence probe. Upon intravenous administration of the probes, MRI assessment of atherosclerotic plaques and diagnostic evaluation were conducted. The application of Flash-3D sequence imaging revealed vascular constriction at lesion sites, accompanied by a gradual signal amplification postprobe injection. T1-weighted imaging of the carotid artery unveiled a progressive signal ratio increase between plaques and controls within 72 h post-administration. Fluorescence imaging of isolated carotid arteries exhibited incremental lesion-to-control signal ratios. Additionally, T1 imaging of the aorta demonstrated an evolving signal enhancement over 48 h. Therefore, the ultrasmall iron oxide nanoparticles hold immense promise for early and noninvasive diagnosis of plaques, providing an avenue for dynamic evaluation over an extended time frame.
Interferon-β decreases LPS-induced neutrophil recruitment to cardiac fibroblasts
Authors: Anfossi Renatto , Vivar Raúl , Ayala Pedro , González-Herrera Fabiola , Espinoza-Pérez Claudio , Osorio José Miguel , Román-Torres Mauricio , Bolívar Samir , Díaz-Araya Guillermo 
Published: September 2023

Introduction: Cardiac fibroblasts (CF) are crucial cells in damaged heart tissues, expressing TLR4, IFN-receptor and responding to lipopolysaccharide (LPS) and interferon-β (IFN-β) respectively. While CF interact with immune cells; however, their relationship with neutrophils remains understudied. Additionally, theimpact of LPS and IFN-β on CF-neutrophil interaction is poorly understood.Methods: Isolated CF from adult rats were treated with LPS, with or without IFN-β. This study examined IL-8 secretion, ICAM-1 and VCAM-1 expression, and neutrophil recruitment, as well as their effects on MMPs activity.Results: LPS triggered increased IL-8 expression and secretion, along with elevated ICAM-1 and VCAM-1 expression, all of which were blocked by TAK-242. Pre-treatment with IFN-β countered these LPS effects. LPS treated CF showed higher neutrophil recruitment (migration and adhesion) compared to unstimulated CF, an effect prevented by IFN-β. Ruxolitinib blocked these IFN-β anti-inflammatory effects, implicating JAK signaling. Analysis of culture medium zymograms from CF alone, and CF-neutrophils interaction, revealed that MMP2 was mainly originated from CF, while MMP9 could come from neutrophils. LPS and IFN-β boosted MMP2 secretion by CF. MMP9 activity in CF was low, and LPS or IFN-β had no significant impact. Pre-treating CF with LPS, IFN-β, or both before co-culture with neutrophils increased MMP2. Neutrophil co-culture increased MMP9 activity, with IFN-β pre-treatment reducing MMP9 compared to unstimulated CF.Conclusion: In CF, LPS induces the secretion of IL-8 favoring neutrophils recruitment and these effects were blocked by IFN-. The results highlight that CF-neutrophil interaction appears to influence the extracellular matrix through MMPs activity modulation.
Characterization of gut microbiota profile in Iranian patients with bipolar disorder compared to healthy controls
Authors: Rashnaei Nassir , Akhavan Sepahi Abbas , Siadat Seyed Davar , Shahsavand-Ananloo Esmaeil , Bahramali Golnaz 
Published: September 2023

IntroductionThe human gut microbiota plays a crucial role in mental health through the gut-brain axis, impacting central nervous system functions, behavior, mood, and anxiety. Consequently, it is implicated in the development of neuropsychiatric disorders. This study aimed to assess and compare the gut microbiota profiles and populations of individuals with bipolar disorder and healthy individuals in Iran. MethodsFecal samples were collected from 60 participants, including 30 bipolar patients (BPs) and 30 healthy controls (HCs), following rigorous entry criteria. Real-time quantitative PCR was utilized to evaluate the abundance of 10 bacterial genera/species and five bacterial phyla.ResultsNotably, Actinobacteria and Lactobacillus exhibited the greatest fold change in BPs compared to HCs at the phylum and genus level, respectively, among the bacteria with significant population differences. Ruminococcus emerged as the most abundant genus in both groups, while Proteobacteria and Bacteroidetes showed the highest abundance in BPs and HCs, respectively, at the phylum level. Importantly, our investigation revealed a lower Firmicutes/Bacteroidetes ratio, potentially serving as a health indicator, in HCs compared to BPs.ConclusionThis study marks the first examination of an Iranian population and provides compelling evidence of significant differences in gut microbiota composition between BPs and HCs, suggesting a potential link between brain functions and the gut microbial profile and population.
Association between gut microbiota and benign prostatic hyperplasia: a two-sample mendelian randomization study
Authors: Xia Di , Wang Jiahui , Zhao Xia , Shen Tao , Ling Li , Liang Yuanjiao 
Published: September 2023

BackgroundRecent researches have shown a correlation between the gut microbiota (GM) and various diseases. However, it remains uncertain whether the relationship between GM and benign prostatic hyperplasia (BPH) is causal.MethodsWe carried out a two-sample Mendelian randomization (MR) analysis, utilizing data from the most extensive GM-focused genome-wide association study by the MiBioGen consortium, with a sample size of 13,266. Data for BPH, encompassing 26,358 cases and 110,070 controls, were obtained from the R8 release of the FinnGen consortium. We employed multiple techniques, such as inverse variance weighted (IVW), constrained maximum likelihood and model averaging methods, maximum likelihood, MR-Pleiotropy RESidual Sum and Outlier (MRPRESSO),MR-Egger, and weighted median methods, to investigate the causal relationship between GM and BPH. To evaluate the heterogeneity among the instrumental variables, Cochran’s Q statistics were employed. Additionally, the presence of horizontal pleiotropy was assessed through the application of both MR-Egger and MR-PRESSO tests. The direction of causality was scrutinized for robustness using the MR-Steiger directionality test. A reverse MR analysis examined the GM previously linked to BPH through a causal relationship in the forward MR assessment.ResultsAccording to the analysis conducted using IVW,Eisenbergiella (odds ratio [OR]=0.92, 95% confidence interval [CI]: 0.85–0.99,P=0.022) and Ruminococcaceae (UCG009) (OR=0.88, 95% CI: 0.79–0.99, P=0.027) were found to reduce the risk of BPH, while Escherichia shigella (OR=1.19, 95% CI: 1.05–1.36, P=0.0082) appeared to increase it. The subsequent reverse MR analysis revealed that the three GM were not significantly influenced by BPH, and there was no noticeable heterogeneity or horizontal pleiotropy among the instrumental variables.Conclusion: These results indicated a causal relationship between Eisenbergiella, Ruminococcaceae (UCG009), and Escherichia shigella and BPH. Further randomized controlled trials are needed to explore more comprehensively the roles and operational mechanisms of these GM in relation to BPH.
Evolution of knockdown resistance (kdr) mutations of Aedes aegypti and Aedes albopictus in Hainan Island and Leizhou Peninsula, China
Authors: Zhao Minghui , Ran Xin , Xing Dan , Liao Yun , Liu Wei , Bai Yu , Zhang Qiang , Chen Kan , Liu Lan , Wu Mingyu , Ma Zu , Gao Jian , Zhang Hengduan , Zhao Tongyan 
Published: September 2023

BackgroundAedes aegypti and Aedes albopictus are important vectors of human arboviruses, transmitting arboviral diseases such as yellow fever, dengue, chikungunya and Zika. These two mosquitoes coexist on Hainan Island and the Leizhou Peninsula in China. Over the past 40 years, the distribution of Ae. albopictus has gradually expanded in these areas, while the distribution of Ae. aegypti has declined dramatically mainly due to the ecological changes and some other factors such as heavy use of insecticide indoor based on endophagic bloodfeeding of the species.MethodsThis study focused on the knockdown resistance (kdr) genes of both mosquitoes, investigated their mutations, and analyzed their haplotype and evolutionary diversity combined with population genetic features based on the ND4/ND5 genes to further elucidate the molecular mechanisms underlying the development of insecticide resistance in both mosquitoes.ResultsThree mutations, S989P, V1016G and F1534C, were found to be present in Ae. aegypti populations, and the three mutations occurred synergistically. Multiple mutation types (F1534C/S/L/W) of the F1534 locus are found in Ae. albopictus populations, with the three common mutations F1534C, F1534S and F1534L all having multiple independent origins. The F1534W (TTC/TGG) mutation is thought to have evolved from the F1534L (TTC/TTG) mutation. The F1534S (TTC/TCG) mutation has evolved from the F1534S (TTC/TCC) mutation. The most common form of mutation at the F1534 locus found in this study was S1534C, accounting for 20.97%, which may have evolved from the F1534C mutation. In addition, a new non-synonymous mutation M1524I and 28 synonymous mutations were identified in Ae. albopictus populations. Correlation analysis showed that the genetic diversity of Ae. aegypti and Ae. albopictus populations did not correlate with their kdr haplotype diversity (P&gt;0.05), but strong gene flow between populations may have contributed to the evolution of the kdr gene.ConclusionThe study of kdr gene evolution in the two mosquito species may help to identify the evolutionary trend of insecticide resistance at an early stage and provide a theoretical basis for improving the efficiency of biological vector control and subsequent research into new insecticides.
Non-revascularized chronic total occlusions impact on substrate and post-ablation results in drug-refractory electrical storm
Authors: Cojocaru Cosmin , Nastasa Alexandrina , Bogdan Stefan , Iorgulescu Corneliu , Deaconu Alexandru , Onciul Sebastian , Vatasescu Radu 
Published: September 2023

Background and aimsThere is limited data concerning the effect of non-revascularized chronic total occlusions (NR-CTOs) after VT ablation. This study sought to evaluate the impact of NR-CTOs after ablation for electrical storm (ES).MethodsPost-hoc retrospective analysis of data regarding 64 consecutive post-myocardial infarction patients (out of which 12 patients with NR-CTOs and 52 without NR-CTOs) undergoing substrate ablation for ES with an available median follow-up of 37.53 (7.25–64.65) months. Ablation result was assessed by inducibility of sustained monomorphic VT (SMVT) during final programmed ventricular stimulation (PVS). The primary endpoints were all-cause mortality and VT/VF recurrences after ablation, respectively, stratified by the presence of NR-CTOs. The secondary endpoint was to assess the predictive effect of NR-CTOs on all-cause mortality and VT/VF recurrences in relation to other relevant prognostic factors.ResultsAt baseline, the presence of NR-CTOs was associated with higher bipolar BZ-to-total scar ratio (72.4% ± 17.9% vs. 52% ± 37.7%, p = 0.022) and more failure to eliminate the clinical VT (25% (3) vs. 0% (0), p &lt; 0.001). During follow-up, overall all-cause mortality and recurrences were more frequent in the NR-CTO subgroup (75% (9) vs. 19.2% (10), log rank p = 0.003 and 58.3% vs. 23.1% (12), log rank p = 0.042 respectively). After adjusting for end-procedural residual SMVT inducibility, NR-CTOs predicted death during follow-up (HR 3.380, p = 0.009) however not recurrence (HR 1.986, p = 0.154).ConclusionsNR-CTO patients treated by RFCA for drug-refractory ES demonstrated a higher ratio of BZ-to-total-scar area. In this analysis, NR-CTO was associated with worse acute procedural results and may as well impact long-term outcomes which should be further assessed in larger patient populations.