bluuebunny/crossref_metadata_2025_split huggingface dataset:
Joint Use of Far‐Infrared and Mid‐Infrared Observation for Sounding Retrievals: Learning From the Past for Upcoming Far‐Infrared Missions
Authors: Xie Yan , Huang Xianglei , Chen Xiuhong , L’Ecuyer Tristan S. , Drouin Brian J. 
Published: March 2023

AbstractAtmosphere and surface properties are routinely retrieved from satellite measurements and extensively used in weather forecast and climate analysis. Satellite missions dedicated to fill the gap of far‐infrared (far‐IR) observations are scheduled to be launched this decade. To explore mid‐infrared (mid‐IR) and far‐IR joint retrievals for the future far‐IR satellite missions, this study uses an optimal‐estimation‐based method to retrieve atmospheric specific humidity and temperature profiles, surface skin temperature, and surface spectral emissivity from the Infrared Interferometer Sounder‐D (IRIS‐D) measurements in 1970, the only existing spaceborne far‐IR spectral observations with global coverage. Based on a set of criteria, two cases in the Arctic, which are most likely under clear‐sky conditions, are chosen for the retrieval experiments. Information content analysis suggests that the retrieved surface skin temperature and the mid‐IR surface spectral emissivity are highly sensitive to the true values while the retrieval estimates of far‐IR surface emissivity are subject to the variation of water vapor abundance. Results show that radiances based on the retrieved state variables are more consistent with the IRIS‐D observations compared to those based on the reanalysis data. Retrieval estimates of the state variables along with retrieval uncertainties generally fall within reasonable ranges. The relative uncertainties of retrieved state variables decrease compared to the a priori relative uncertainties. In addition, the necessity to retrieve surface emissivity is corroborated by a parallel retrieval experiment assuming a blackbody surface emissivity that has revealed significant distortions of retrieved specific humidity and temperature profiles in the Arctic lower troposphere.
Near‐Bed Sediment Transport Processes During Onshore Bar Migration in Large‐Scale Experiments: Comparison With Offshore Bar Migration
Authors: Grossmann Florian , Hurther David , van der Zanden Joep , Sánchez‐Arcilla Agustín , Alsina José M. 
Published: March 2023

AbstractDetailed information on nearshore sediment transport processes during onshore bar migration were obtained from large‐scale laboratory experiments with bichromatic wave groups on a relatively steep initial beach slope (1:15). Detailed measurements of velocity and sand concentration near the bed from shoaling up to the outer breaking zone including suspended sediment and sheet flow transport are presented. The analysis focuses on onshore migration under an accretive wave condition but comparison to an erosive condition highlights important differences. Decomposition shows that total transport mainly results from a balance of short wave‐related, bedload onshore transport and current‐related, suspended offshore transport. When comparing the accretive to the more energetic erosive condition, the balance shifts toward onshore transport, and onshore migration, because the short wave‐related transport does not decrease as much as the current‐related transport. This is related to the effects of skewness and asymmetry combined with less sediment suspension in the water column and undertow magnitude under the accretive condition. Transports from streaming in the wave boundary layer and from infragravity waves become visible but only play a subordinate role. Identified priorities for numerical model development include parametrization of wave nonlinearity effects and better description of wave breaking and its influences on sediment suspension.
Neurofilament-light chain quantification by Simoa and Ella in plasma from patients with dementia: a comparative study
Authors: Truffi Marta , Garofalo Maria , Ricciardi Alessandra , Cotta Ramusino Matteo , Perini Giulia , Scaranzin Silvia , Gastaldi Matteo , Albasini Sara , Costa Alfredo , Chiavetta Viola , Corsi Fabio , Morasso Carlo , Gagliardi Stella 
Published: March 2023

AbstractNeurofilament light chains (NfL) are neuron-specific cytoskeletal proteins whose plasmatic concentrations have been explored as a clinically useful marker in several types of dementia. Plasma concentrations of NfL are extremely low, and just two assays are commercially available for their study: one based on the SiMoA technology and one based on Ella. We thus studied plasma levels of NfL with both platforms to check the correlation between them and to assess their potential in the diagnosis of neurodegeneration. Plasma NfL levels were measured on 50 subjects: 18 healthy controls, 20 Alzheimer’s disease, and 12 frontotemporal dementia patients. Ella returned plasmatic NfL levels significantly higher than SiMoA, however the results were strongly correlated (r = 0.94), and a proportional coefficient of 0.58 between the two assays was calculated. Both assays detected higher plasma NfL levels in patients with dementia than in the control group (p < 0.0001) and allowed their discrimination with excellent diagnostic performance (AUC > 0.95). No difference was found between Alzheimer’s and Frontotemporal dementia either using SiMoA or Ella. In conclusion, both the analytical platforms resulted effective in analysing plasma levels of NfL. However, the correct interpretation of results requires the precise knowledge of the assay used.
Genome scale analysis of 1-aminocyclopropane-1-carboxylate oxidase gene family in G. barbadense and its functions in cotton fiber development
Authors: Yousaf Samina , Rehman Tanzeela , Tabassum Bushra , Aftab Faheem , Qaisar Uzma 
Published: March 2023

AbstractA class of proteins, 1-aminocyclopropane-1-carboxylate oxidase (ACO), is required in the final step of production of ethylene from its immediate precursor 1-aminocyclopropane-1-carboxylic acid (ACC). Despite the crucial and regulatory role of ACO gene family in the fiber development, it has not been thoroughly analyzed and annotated in G. barbadense genome. In the present study, we have identified and characterized all isoforms of ACO gene family from genomes of Gossypium arboreum, G. barbadense, G. hirsutum and G. raimondii. Phylogenetic analysis classified all ACO proteins into six distinct groups on the basis of maximum likelihood. Gene locus analysis and circos plots indicated the distribution and relationship of these genes in cotton genomes. Transcriptional profiling of ACO isoforms in G. arboreum, G. barbadense and G. hirsutum fiber development exhibited the highest expression in G. barbadense during early fiber elongation. Moreover, the accumulation of ACC was found highest in developing fibers of G. barbadense in comparison with other cotton species. ACO expression and ACC accumulation correlated with the fiber length in cotton species. Addition of ACC to the ovule cultures of G. barbadense significantly increased fiber elongation while ethylene inhibitors hindered fiber elongation. These findings will be helpful in dissecting the role of ACOs in cotton fiber development and pave a way towards genetic manipulations for fiber quality improvement.
Correlation between patient-specific quality assurance in volumetric modulated arc therapy and 2D dose image features
Authors: Guo Yixiao , Hu Jinyan , Li Yang , Ran Juntao , Cai Hongyi 
Published: March 2023

AbstractIn radiotherapy, air-filled ion chamber detectors are ubiquitously used in routine dose measurements for treatment planning. However, its use has been restricted by intrinsic low spatial resolution barriers. We developed one procedure for patient-specific quality assurance (QA) in arc radiotherapy by coalescing two adjacent measurement images into a single image to improve spatial resolution and sampling frequency, and investigated how different spatial resolutions affect the QA results. PTW 729 and 1500 ion chamber detectors were used for dosimetric verification via coalescing two measurements with 5 mm-couch shift and the isocenter, and only isocenter measurement, which we call coalescence and standard acquisition (SA). Statistical process control (SPC), process capability analysis (PCA), and receiver operating characteristic (ROC) curve were used to compare the performance of the two procedures in determining tolerance levels and identifying clinically relevant errors. By analyzing 1256 γ values calculated on interpolated data points, our results indicated that detector 1500 showed higher averages in coalescence cohorts at different tolerance criteria and the dispersion degrees were spread out smaller. Detector 729 yielded a slightly lower process capability of 0.79, 0.76, 1.10, and 1.34, but detector 1500 exhibited somewhat different results of 0.94, 1.42, 1.19, and 1.60 in magnitude. The results of SPC individual control chart showed that cases in coalescence cohorts with γ values lowering its lower control limit (LCL) were greater than those in SA cohorts for detector 1500. A combination of the width of multi-leaf collimator (MLC) leaf, the cross-sectional area of the single detector, and the spacing between adjacent detectors might lead to discrepancies in percent γ values across diverse spatial resolution scenarios. The accuracy of reconstructed volume dose is mainly determined by the interpolation algorithm used in dosimetric systems. The magnitude of filling factor in the ion chamber detectors determined its ability to detect dose deviations. SPC and PCA results indicated that coalescence procedure could detect more potential failure QA results than SA while enhancing action thresholds.
Efficacy of ceftazidime in a murine model following a lethal aerosol exposure to Burkholderia pseudomallei
Authors: Pfefferle Denise A. , Hackett Michael , Anderson Michael S. , Gibbs Seth , Henning Lisa N. , Joice April C. , Meister Gabriel T. 
Published: March 2023

AbstractMelioidosis is an endemic disease in numerous tropical regions. Additionally, the bacterium that causes melioidosis, Burkholderia pseudomallei, has potential to be used as a biological weapon. Therefore, development of effective and affordable medical countermeasures to serve regions affected by the disease and to have medical countermeasures available in the event of a bioterrorism attack remains critical. The current study evaluated the efficacy of eight distinct acute phase ceftazidime treatment regimens administered therapeutically in the murine model. At the conclusion of the treatment period, survival rates were significantly greater in several of the treated groups when compared to the control group. Pharmacokinetics of a single dose of ceftazidime were examined at 150 mg/kg, 300 mg/kg, and 600 mg/kg and were compared to an intravenous clinical dose administered at 2000 mg every eight hours. The clinical dose has an estimated 100% fT > 4*MIC which exceeded the highest murine dose of 300 mg/kg every six hours at 87.2% fT > 4*MIC. Based upon survival at the end of the treatment regimen and supplemented by pharmacokinetic modeling, a daily dose of 1200 mg/kg of ceftazidime, administered every 6 h at 300 mg/kg, provides protection in the acute phase of inhalation melioidosis in the murine model.
The effects of sexual shame, emotion regulation and gender on sexual desire
Authors: Sævik K. W. , Konijnenberg C. 
Published: March 2023

AbstractSexual desire is of importance to sexual health, functioning, and well-being. Although an increasing number of studies address disorders related to sexual functioning, there is still a limited understanding of the underlying individual factors affecting sexual desire. The aim of the current study was to investigate the effect of sexual shame, emotion regulation strategies, and gender on sexual desire. In order to investigate this, sexual desire, expressive suppression, cognitive reappraisal, and sexual shame was measured in 218 Norwegian participants using the Emotion Regulation Questionnaire-10, the Sexual Desire Inventory-2, and the Sexual Shame Index-Revised. A multiple regression analysis indicated that cognitive reappraisal predicted sexual desire, β = 0.343, (218) = 5.09, p < 001, CI [0.407, 0.920], whereas sexual shame and expressive suppression were unrelated to sexual desire. Men scored significantly higher than women on expressive suppression, F(1, 216) = 24.968, p < 0.001; partial η2 = 0.104. The current study did not find any significant differences between women and men on cognitive reappraisal, sexual desire or sexual shame, all p > 0.05. Results from the current study indicates that the inclination toward cognitive reappraisal as a preferred emotion regulation strategy may positively affect the strength of sexual desire.
Prediction of the visit and occupy of the sika deer (Cervus nippon) during the summer season using a virtual ecological approach
Authors: Osawa Takeshi , Tsutsumida Narumasa , Iijima Hayato , Okabe Kimiko 
Published: March 2023

AbstractPrediction of the spaces used by animals is an important component of wildlife management, but requires detailed information such as animal visit and occupy in a short span of the target species. Computational simulation is often employed as an effective and economical approach. In this study, the visit and occupy of sika deer (Cervus nippon) during the plant growing season were predicted using a virtual ecological approach. A virtual ecological model was established to predict the visit and occupy of sika deer based on the indices of their food resources. The simulation results were validated against data collected from a camera trapping system. The study was conducted from May to November in 2018 in the northern Kanto region of Japan. The predictive performance of the model using the kernel normalized difference vegetation index (kNDVI) was relatively high in the earlier season, whereas that of the model using landscape structure was relatively low. The predictive performance of the model using combination of the kNDVI and landscape structure was relatively high in the later season. Unfortunately, visit and occupy of sika deer could not predict in November. The use of both models, depending on the month, achieved the best performance to predict the movements of sika deer.
Can Retrieval Practice Facilitate Verb Learning in Children With Developmental Language Disorder and Their Peers With Typical Language Development?
Authors: Leonard Laurence B. , Deevy Patricia , Horvath Sabrina , Christ Sharon L. , Karpicke Jeffrey , Kueser Justin B. 
Published: March 2023

Purpose:
Children with developmental language disorder (DLD) have well-documented verb learning difficulties. In this study, we asked whether the inclusion of retrieval practice during the learning period would facilitate these children's verb learning relative to a similar procedure that provided no retrieval opportunities.

Method:

Eleven children with DLD (
M
age
= 60.09 months) and 12 children with typical language development (TD;
M
age
= 59.92 months) learned four novel verbs in a repeated spaced retrieval (RSR) condition and four novel verbs in a repeated study (RS) condition. The words in the two conditions were heard an equal number of times, in the context of video-recorded actors performing novel actions.

Results:

Recall testing immediately after the learning period and 1 week later revealed greater recall for novel verbs in the RSR condition than for novel verbs in the RS condition. This was true for both groups, and for immediate as well as 1-week testing. The RSR advantage remained when children had to recall the novel verbs while watching new actors perform the novel actions. However, when tested in contexts requiring the children to inflect the novel verbs with –
ing
for the first time, the children with DLD were much less likely to do so than their peers with TD. Even words in the RSR condition were only inconsistently inflected.

Conclusions:
Retrieval practice provides benefits to verb learning—an important finding given the challenges that verbs present to children with DLD. However, these benefits do not appear to automatically translate to the process of adding inflections to newly learned verbs but rather appear to be limited to the operations of learning the verbs' phonetic forms and mapping these forms onto associated actions.
Acceptance factors of telemedicine technology during Covid‐19 pandemic among health professionals: A qualitative study
Authors: Mohammed Rouidi , Elmajid Elouadi Abd , Amine Hamdoune , Khadija Choujtani 
Published: March 2023

AbstractObjectiveHealth professionals are the main users of telemedicine systems, and their acceptance will contribute to the successful implementation of this technology. The objective of this study is to provide a better understanding of the issues surrounding the acceptance of telemedicine technology by Moroccan health professionals in the public sector, in the preparation for a possible generalization of this technology in Morocco.MethodFollowing a literature review, the authors mobilized a modified version of the unified model of technology acceptance and use, to explain and understand the determinants of health professionals’ intention to accept telemedicine technology. The authors’ methodology is based on a qualitative analysis and is primarily based on data obtained through semi‐structured interviews with health professionals, who the authors believe are the primary actors in the acceptance of this technology within Moroccan hospitals.ResultsThe authors’ results suggest that performance expectancy, effort expectancy, compatibility, facilitating conditions, perceived incentives, and social influence have a significant positive impact on health professionals’ behavioural intention to accept telemedicine technology.Practical implicationsFrom a practical point of view, the results of this study can help the government, organizations responsible for the implementation of telemedicine, and policymakers to understand the key factors that may affect the behaviour of future users of this technology, and to develop very specific strategies and policies for a successful generalization.
Simulation of CH3OH ice UV photolysis under laboratory conditions
Authors: Rocha W. R. M. , Woitke P. , Pilling S. , Thi W.-F. , Jørgensen J. K. , Kristensen L. E. , Perotti G. , Kamp I. 
Published: March 2023

Context. Methanol is the most complex molecule that is securely identified in interstellar ices. It is a key chemical species for understanding chemical complexity in astrophysical environments. Important aspects of the methanol ice photochemistry are still unclear, such as the branching ratios and photodissociation cross sections at different temperatures and irradiation fluxes.
Aims. This work aims at a quantitative agreement between laboratory experiments and astrochemical modelling of the CH3OH ice UV photolysis. Ultimately, this work allows us to better understand which processes govern the methanol ice photochemistry present in laboratory experiments.
Methods. We used the code ProDiMo to simulate the radiation fields, pressures, and pumping efficiencies characteristic of laboratory measurements. The simulations started with simple chemistry consisting only of methanol ice and helium to mimic the residual gas in the experimental chamber. A surface chemical network enlarged by photodissociation reactions was used to study the chemical reactions within the ice. Additionally, different surface chemistry parameters such as surface competition, tunnelling, thermal diffusion, and reactive desorption were adopted to check those that reproduce the experimental results.
Results. The chemical models with the code ProDiMo that include surface chemistry parameters can reproduce the methanol ice destruction via UV photodissociation at temperatures of 20, 30, 50, and 70 K as observed in the experiments. We also note that the results are sensitive to different branching ratios after photolysis and to the mechanisms of reactive desorption. In the simulations of a molecular cloud at 20 K, we observed an increase in the methanol gas abundance of one order of magnitude, with a similar decrease in the solid-phase abundance.
Conclusions. Comprehensive astrochemical models provide new insights into laboratory experiments as the quantitative understanding of the processes that govern the reactions within the ice. Ultimately, these insights can help us to better interpret astronomical observations.
Velocity measurement in the extensive [OIII] emission region 1.2° south-east of M 31
Authors: Amram P. , Adami C. , Epinat B. , Chemin L. 
Published: March 2023

Context. The discovery of a broad, ∼1.5° long filamentary [OIII] 5007 emission ∼1.2° south-east of the M 31 nucleus has recently been reported. More than 100 hours of exposures of a wide field (3.48° × 2.32°) have allowed this pioneering detection based on 30 Å narrow-band filters and several small refractors equipped with large cameras.
Aims. We report a first velocity measurement in this extensive [OIII] emission line region.
Methods. We used the low-resolution spectrograph MISTRAL (R ∼ 750), a facility of the Haute-Provence Observatory 193 cm telescope. The velocity measurement is based on the Hα, [NII], [SII] and [OIII] lines.
Results. The best solution to fit the spectrum indicates that the Hα and [OIII] emissions are at the same heliocentric line-of-sight velocity of −96±4 km s−1. This was measured within an area of ∼250 arcsec2 selected on a bright knot along the long filament of ∼1.5°, together with a [OIII]5007 surface brightness of 4.2±2.1×10−17 erg s−1 cm−2 arcsec−2. This agrees moderately well with the previous measurement. We also estimated the Hα/[NII] line ratio as ∼1.1.
Conclusions. The radial velocities at which the Hα and [OIII] lines were detected seem to show that these hydrogen and oxygen atoms belong to the same layer, but we cannot exclude that another weaker [OIII] line, belonging to another structure, that is, at another velocity, is below our detection threshold. Different scenarios have been considered to explain this filamentary structure. The extra-galactic origin was excluded in favour of Galactic origins. We tentatively assume that this filament is a piece of a supernova remnant located at a distance of ∼0.7 kpc from the Sun, of which we only see a small fraction of the shells with a radius of ∼35 pc. The progenitor may be along the line of sight of the galaxy M 31, but this observation might also just be part of a large-scale filamentary structure that should be investigated further.
Die Äskulapnatter – Symbol der
Heilkundigen
Authors: Brendieck-Worm Cäcilia 
Published: March 2023

ZusammenfassungDie Äskulapnatter, Symbol der Heilung, ist in ihrem ursprünglich
weit ausgedehnten Verbreitungsraum selten geworden. Die ungiftige Schlange
bevorzugt feuchte, warme Habitate mit ausreichend
Unterschlupfmöglichkeiten in verfallenem Gemäuer oder lichtem
Buschwerk. Um die Bestände der stark gefährdeten Art zu
erhalten, muss man für geeignete Brut-, Sonnen- und
Überwinterungsplätze sorgen und den Verlusten durch
Straßenverkehr und Mäharbeiten vorbeugen.