bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new validated model of leadership development in higher education; empirical assessment using universal attributes of spiritual intelligence
Authors: Prabhu Chetan , Mehta Mita 
Published: May 2023

PurposeHigher education institutions aim for the holistic development of students to cope with the changing global context. The present study aims to devise a model of leadership development among higher education students by validating the model conceptually and testing it empirically. Attributes of Spiritual Intelligence (SI) are empirically evaluated for leadership development post its conceptual validation.Design/methodology/approachThis article examined current theoretical frameworks and gaps in the literature. A total of 810 students were approached from Indian Higher education institutions for study. Data has been examined using the exploratory and then confirmatory factor analysis techniques to check the validity and reliability of the measuring instrument.FindingsThe empirical findings confirm that the eight new spiritual intelligence attributes defined and validated through this study can have a significant impact on the leadership development of higher education students.Practical implicationsEducational researchers have often found the construct of spiritual intelligence challenging to comprehend and implement in higher education institutions. The present study findings can be of great value to higher education institutions that will recognize the importance of spiritual values in holistic development including leadership development.Originality/valueThis paper initiates and validate a universal set of attributes of spiritual intelligence in the higher education domain that can be useful for leadership development. The uniqueness of this paper lies in the fact that the eight new attributes of SI defined are easy to comprehend and practical to use in daily academic life, and can be used by HEIs students irrespective of their spiritual beliefs. A validated model at one university could be replicated at other universities in India and around the world, not only for students but also for educators and administrators as well.
Government policy response to COVID-19 and bank performance: a comparison between Islamic and conventional banks
Authors: Yudaruddin Rizky 
Published: May 2023

Purpose
This study aims to examine the joint impact of the COVID-19 pandemic and the government response on the performance of Islamic and conventional banks.

Design/methodology/approach
Data were collected from a sample of 94 conventional and 14 Islamic banks in Indonesia from March 2020 to September 2021. The system generalized methods of moments estimation is used to analyze the data.

Findings
This study finds robust results regarding the negative impact of the COVID-19 pandemic and the positive effects of government responses to COVID-19 pandemic on bank performance in Indonesian banking. Moreover, in line with the rise in confirmed COVID-19 cases, a higher government policy responses index improves bank performance, both in conventional and Islamic banks.

Practical implications
This paper highlights the importance of the government policy responses index to absorb the negative impact of the COVID-19 outbreak on banking performance.

Originality/value
This paper provides novel insights into the joint impact of the COVID-19 pandemic and government responses to COVID-19 pandemic on bank performance between conventional and Islamic banks.
Bending strength of full-scale wide-flange steel beams considering strain rate effects at elevated temperatures
Authors: Kimura Kei , Onogi Takeshi , Yotsumoto Naoya , Ozaki Fuminobu 
Published: May 2023

PurposeIn this study, the effects of strain rate on the bending strength of full-scale wide-flange steel beams have been examined at elevated temperatures. Both full-scale loaded heating tests under steady-state conditions and in-plane numerical analysis using a beam element have been employed.Design/methodology/approachThe load–deformation relationships in 385 N/mm2-class steel beam specimens was examined using steady-state tests at two loading rate values (0.05 and 1.00 kN/s) and at two constant member temperatures (600 and 700 °C). Furthermore, the stress–strain relationships considering the strain rate effects were proposed based on tensile coupon test results under various strain rate values. The in-plane elastoplastic numerical analysis was conducted considering the strain rate effect.FindingsThe experimental test results of the full-scale steel beam specimens confirmed that the bending strength increased with increase in strain rate. In addition, the analytical results agreed relatively well with the test results, and both strain and strain rate behaviours of a heated steel member, which were difficult to evaluate from the test results, could be quantified numerically.Originality/valueThe novelty of this study is the quantification of the strain rate effect on the bending strength of steel beams at elevated temperatures. The results clarify that the load–deformation relationship of steel beams could be evaluated by using in-plane analysis using the tensile coupon test results. The numerical simulation method can increase the accuracy of evaluation of the actual behaviour of steel members in case of fire.
3D bioprinting in the era of 4th industrial revolution – insights, advanced applications, and future prospects
Authors: Bin Rashid Adib , Uddin Abu Saleh Md. Nakib , Azrin Fahima Akter , Saad Khondker Safin Kaosar , Hoque Md Enamul 
Published: May 2023

Purpose
The main objective of this paper is to illustrate an analytical view of different methods of 3D bioprinting, variations, formulations and characteristics of biomaterials. This review also aims to discover all the areas of applications and scopes of further improvement of 3D bioprinters in this era of the Fourth Industrial Revolution.

Design/methodology/approach
This paper reviewed a number of papers that carried evaluations of different 3D bioprinting methods with different biomaterials, using different pumps to print 3D scaffolds, living cells, tissue and organs. All the papers and articles are collected from different journals and conference papers from 2014 to 2022.

Findings
This paper briefly explains how the concept of a 3D bioprinter was developed from a 3D printer and how it affects the biomedical field and helps to recover the lack of organ donors. It also gives a clear explanation of three basic processes and different strategies of these processes and the criteria of biomaterial selection. This paper gives insights into how 3D bioprinters can be assisted with machine learning to increase their scope of application.

Research limitations/implications
The chosen research approach may limit the generalizability of the research findings. As a result, researchers are encouraged to test the proposed hypotheses further.

Practical implications
This paper includes implications for developing 3D bioprinters, developing biomaterials and increasing the printability of 3D bioprinters.

Originality/value
This paper addresses an identified need by investigating how to enable 3D bioprinting performance.
Copycatting the smell of death: Deciphering the role of cadaveric scent components used by detection dogs to locate human remains
Authors: Martin Clément , Malević Marta , Diederich Claire , Verheggen François 
Published: May 2023

AbstractHuman remains detection dogs (HRDD) are commonly used by law enforcement agencies to search for cadavers. Biological material is typically used as a training stimulus, also called aids, to train dogs to recognize the smell of cadavers. While HRDD training approaches have received extensive attention, information remains limited on the olfactory cues used to train them. Here, we aimed to decipher the chemical basis of detection dog olfaction. Five specific objectives were explored to precise whether the composition or the concentration of the training aids drives the HRDDs responses. We recorded the behavioral responses of four HRDDs exposed to different cadaveric‐like smells. We found that HRDDs recognized a simplified synthetic aid composed of cadaveric compounds. The lowest concentration at which HRDDs continued to perceive the cadaveric smell was determined. HRDDs were not impacted by slight modifications to the chemical composition of a blend of odors that they have been trained with. HRDDs associated sulfur and nitrogen compounds as human cadaver. Our findings highlight a lack of specificity of HRDDs to cadaveric compounds, which could lead to error of detection. Moreover, all dogs did not positively respond to the same blends, despite being trained with the same aids and procedure. However, we confirmed that dogs could be trained with a simplified blend of molecules. The chemical composition of a training aid has, therefore, high consequences on the performance of the trained animal, and this conclusion opens additional questions regarding olfaction‐based detection animals.
Effects of processing methods on the aroma constituents of hihatsumodoki (Piper retrofractum Vahl)
Authors: Oe Moena , Wada Koji , Asikin Yonathan , Arakaki Mika , Horiuchi Masahiro , Takahashi Makoto 
Published: May 2023

AbstractHihatsumodoki (Piper retrofractum Vahl) is a traditional spice from Okinawa (Japan) that can be processed in different ways to create the desired flavor. Herein, we examined the effects of processing (sun‐drying, oven‐drying, roasting, and steaming) on the volatile aroma constituents of hihatsumodoki fruits. Among the 106 chromatographic peaks observed in total, 58 were assigned to known aroma compounds. The relative contents of terpenes, for example, linalool, β‐caryophyllene, α‐caryophyllene, and germacrene D, ranged from 57.6% to 88.1%. Sun‐drying decreased the content of aldehydes such as hexanal and trans‐2‐hexenal but did not significantly affect the total content of aroma compounds. The amount of aroma compounds released during oven‐drying and roasting increased with temperature up to a certain point (90°C) and decreased at an excessively high temperature of 180°C. High‐temperature roasting generated Maillard reaction products such as furans and furanones, which could impart sweet caramel odors. Steamed fruits had the lowest content of aroma compounds, which was ascribed to the loss of these compounds to vapor. Meanwhile, drying steamed fruits resulted in an approximately 3.6‐fold increase in their aroma compound content, and the content of sesquiterpenes in the steamed‐dried fruits was similar to that in fruits exposed to high temperatures. The effects of processing on aroma quality were visualized using multivariate statistical analysis. The aroma characteristics of roasted (180°C), steamed, and steamed‐dried fruits were different from those of the control. The combined findings provide useful information for the selection of processing methods to achieve the desired flavor of hihatsumodoki.Practical Application: This study reveals the effects of different processing methods on the aroma profile of hihatsumodoki (Piper retrofractum Vahl), a subtropical spice from Okinawa (Japan). The results facilitate the selection of preferred hihatsumodoki flavors for household and industrial applications in foods and beverages. In addition, they inspire research on the processing‐induced flavor changes of other tropical or subtropical spices.
Circulating leptin level in osteoarthritis and associations between leptin receptor polymorphisms and disease susceptibility: A meta‐analysis
Authors: Lee Young Ho , Song Gwan Gyu 
Published: May 2023

AbstractObjectiveThis study aimed to systemically review the evidence on the relationship between the circulating leptin levels and osteoarthritis (OA), and the association between leptin and leptin receptor (LEPR) polymorphisms and OA susceptibility.MethodsTo find relevant papers (up to February 2023) examining the association between circulating leptin levels, LEPR polymorphisms, and OA, the PUBMED, EMBASE, and Cochrane databases were searched. We performed a meta‐analysis to examine the levels of synovial and serum/plasma leptin in OA patients compared with healthy controls, as well as the relationship between OA and LEPR polymorphisms.ResultsData from 15 investigations, totaling 2197 patients with OA and 2546 controls, were included in the meta‐analysis. There were statistically significant differences in the levels of circulating leptin between the OA and control groups (standardized mean difference [SMD] 2.178, 95% confidence interval [CI] 1.208‐3.139, P = 0.001). Leptin levels were also substantially greater in European, Asian, and Arab groups among OA patients. After adjusting for age, sex, and/or body mass index, the leptin levels of patients with OA were significantly higher. Similarly, regardless of sample size (n < 100 and n ≥ 100) or year of publication, leptin levels were considerably higher in the OA group. In addition, the synovial leptin level was greater in the OA group than in the control group (SMD 0.783; 95% CI 0.247‐1.319, P = 0.004). In the LEPR rs1137101 polymorphism, the OA and AA genotypes were significantly associated (odds ratio 0.282, 95% CI 0.126‐0.629, P = 0.002), according to the meta‐analysis. Ethnic stratification revealed an association between OA and the LEPR rs1137101 AA genotype in Asian and Arab populations.ConclusionThe results of this meta‐analysis indicate that patients with OA had considerably greater levels of circulating leptin than did control individuals. In addition, synovial leptin levels were greater in OA patients than in healthy individuals, and the LEPR rs1137101 polymorphism was linked to an increased risk of developing OA. These results imply that leptin participates in the onset and progression of OA.
Pembrolizumab plus chemotherapy in Japanese patients with metastatic squamous non‐small‐cell lung cancer in KEYNOTE‐407
Authors: Sugawara Shunichi , Tanaka Kentaro , Imamura Fumio , Yamamoto Nobuyuki , Nishio Makoto , Okishio Kyoichi , Hirashima Tomonori , Tanaka Hiroshi , Fukuhara Tatsuro , Nakahara Yasuharu , Kurata Takayasu , Katakami Nobuyuki , Okada Morihito , Horinouchi Hidehito , Udagawa Hibiki , Kasahara Kazuo , Satouchi Miyako , Saka Hideo , Tokito Takaaki , Hosomi Yukio , Aoe Keisuke , Kishi Kazuma , Ohashi Kadoaki , Yokoyama Takuma , Adachi Noriaki , Noguchi Kazuo , Schwarzenberger Paul , Kato Terufumi 
Published: May 2023

AbstractThe global phase III KEYNOTE‐407 (NCT02775435) trial showed that pembrolizumab plus chemotherapy prolonged overall and progression‐free survival (OS/PFS) versus placebo plus chemotherapy in patients with metastatic squamous non‐small‐cell lung cancer (NSCLC). We present outcomes of patients from Japan enrolled in KEYNOTE‐407. Patients were randomized 1:1 to receive pembrolizumab 200 mg or placebo with paclitaxel 200 mg/m2 every 3 weeks (Q3W) or nab‐paclitaxel 100 mg/m2 (weekly) plus carboplatin area under the concentration‐time curve of 6 mg/mL/min Q3W for four cycles, followed by pembrolizumab or placebo Q3W for a total of 35 cycles. Primary end‐points were OS and PFS per RECIST version 1.1 by blinded independent central review. Fifty patients were randomized at Japanese sites (pembrolizumab plus chemotherapy, n = 22; placebo plus chemotherapy, n = 28). Median follow‐up time at data cut‐off (May 9, 2019) was 15.1 (range, 0.5–24.0) months. Median OS (95% confidence interval [CI]) was 17.3 (12.5–not reached) versus 11.0 (8.6–19.5) months in the pembrolizumab plus chemotherapy versus placebo plus chemotherapy group (hazard ratio [HR] 0.56; 95% CI, 0.27–1.15). Median PFS (95% CI) was 8.3 (6.1–13.0) versus 7.2 (3.9–8.8) months (HR 0.65; 95% CI, 0.35–1.23). Grade 3–5 adverse events (AEs) occurred in 86% and 75% of patients, respectively. There were three fatal AEs, two of which were treatment‐related (one from each treatment group, pneumonitis and pulmonary hemorrhage). Efficacy and safety outcomes were consistent with the global study and support the use of pembrolizumab plus chemotherapy in Japanese patients with metastatic squamous NSCLC.
A prospective case series on the efficacy of a cross‐linked collagen matrix to increase buccal soft tissue thickness at large edentulous gaps: One‐year results
Authors: Surdiacourt Lenz , Cosyn Jan 
Published: May 2023

AbstractObjectiveThe objective of this study is to assess profilometric changes following soft tissue augmentation with a cross‐linked porcine‐derived collagen matrix (CMX) at large edentulous gaps of at least two units.Materials and methodsSystemically healthy, nonsmoking patients with a large edentulous gap of at least two units demonstrating a horizontal soft tissue defect, were enrolled in a prospective case series. Soft tissue augmentation was performed in a one‐stage approach with a 6 mm thick CMX at the time of implant placement. The primary outcome was the change in buccal soft tissue profile (BSP) at a mesial, central, and distal area of interest (AOI) up to 1 year when compared to the preoperative situation based on superimposed digital surface models. Secondary outcomes included the horizontal dimension of the soft tissue defect, complications, and marginal bone loss (MBL).ResultsFifteen patients (eight females; mean age 58.73 years) were enrolled and 13 could be re‐assessed at 1‐year follow‐up. The mean linear increase in BSP at 1 year was 0.66 mm (98.3% CI: 0.37–0.94), 0.80 mm (98.3% CI: 0.39–1.22), and 0.69 mm (98.3% CI: 0.32–1.06) at the mesial, central, and distal AOI, respectively. Substantial shrinkage of about 75% was observed in all areas between augmentation and 1‐year follow‐up. Even though 11 of 13 sites were fully augmented immediately postoperative, a soft tissue defect recurred in all sites at 1‐year follow‐up with a mean deficit of 2.30 mm. Altogether, 25% of the original soft tissue defect was eliminated by soft tissue augmentation. CMX was safe since no postoperative complications occurred and MBL was limited (0.70 mm).ConclusionCMX is efficacious for horizontal soft tissue augmentation at large edentulous gaps. However, considerable graft resorption may be expected, and the clinical relevance of the augmentation may be questionable since all patients demonstrated a recurring and considerable soft tissue defect 1 year after surgery.
Integrated analysis of the association between methionine cycle and risk of moyamoya disease
Authors: Li Junsheng , He Qiheng , Liu Chenglong , Zeng Chaofan , Tao Chuming , Zhai Yuanren , Liu Wei , Zhang Qian , Wang Rong , Zhang Yan , Ge Peicong , Zhang Dong , Zhao Jizong 
Published: May 2023

AbstractObjectiveThe role of methionine (Met) cycle in the pathogenesis and progression of cardiovascular and cerebrovascular diseases has been established, but its association with moyamoya disease (MMD) has rarely been studied. This study aimed to analyze the levels of Met cycle‐related metabolites and constructed a risk model to explore its association with the risk of MMD.MethodsIn this prospective study, a total of 302 adult MMD patients and 88 age‐matched healthy individuals were consecutively recruited. The serum levels of Met cycle‐related metabolites were quantified by liquid chromatography‐mass spectrometry (LC–MS). Participants were randomly divided into training set and testing set at a ratio of 1:1. The training set was used to construct the risk score model by LASSO regression. The association between Met cycle‐related risk score and the risk of MMD was analyzed using logistic regression and assessed by ROC curves. The testing set was used for validation.ResultsThe levels of methionine sulfoxide and homocysteine were significantly increased, while the levels of betaine and choline were significantly decreased in MMD and its subtypes compared to healthy controls (p < 0.05 for all). The training set was used to construct the risk model and the risk score of each participant has been calculated. After adjusting for potential confounders, the risk score was independently associated with the risk of MMD and its subtypes (p < 0.05 for all). We then divided the participants into low‐risk and high‐risk groups, the high‐risk score was significantly associated with the risk of MMD and its subtypes (p < 0.05 for all). The risk scores were further assessed as tertiles, the highest tertile was significantly associated with a higher risk of MMD and its subtypes compared to the lowest (p < 0.05 for all). The results were validated in the testing set.ConclusionThis study has constructed and validated a risk model based on Met cycle‐related metabolites, which was independently associated with the risk of MMD and its subtypes. The findings provided a new perspective on the risk evaluation and prevention of MMD.
Chunking Versus Transitional Probabilities: Differentiating Between Theories of Statistical Learning
Authors: Emerson Samantha N. , Conway Christopher M. 
Published: May 2023

AbstractThere are two main approaches to how statistical patterns are extracted from sequences: The transitional probability approach proposes that statistical learning occurs through the computation of probabilities between items in a sequence. The chunking approach, including models such as PARSER and TRACX, proposes that units are extracted as chunks. Importantly, the chunking approach suggests that the extraction of full units weakens the processing of subunits while the transitional probability approach suggests that both units and subunits should strengthen. Previous findings using sequentially organized, auditory stimuli or spatially organized, visual stimuli support the chunking approach. However, one limitation of prior studies is that most assessed learning with the two‐alternative forced‐choice task. In contrast, this pre‐registered experiment examined the two theoretical approaches in sequentially organized, visual stimuli using an online self‐paced task—arguably providing a more sensitive index of learning as it occurs—and a secondary offline familiarity judgment task. During the self‐paced task, abstract shapes were covertly organized into eight triplets (ABC) where one in every eight was altered (BCA) from the canonical structure in a way that disrupted the full unit while preserving a subunit (BC). Results from the offline familiarity judgment task revealed that the altered triplets were perceived as highly familiar, suggesting the learned representations were relatively flexible. More importantly, results from the online self‐paced task demonstrated that processing for subunits, but not unit‐initial stimuli, was impeded in the altered triplet. The pattern of results is in line with the chunking approach to statistical learning and, more specifically, the TRACX model.
Prediction From Minimal Experience: How People Predict the Duration of an Ongoing Epidemic
Authors: Lu Yi‐Long , Lu Yang‐Fan , Han Zhuo Rachel , Qin Shaozheng , Zhang Xin , Yi Li , Zhang Hang 
Published: May 2023

AbstractPeople are known for good predictions in domains they have rich experience with, such as everyday statistics and intuitive physics. But how well can they predict for problems they lack experience with, such as the duration of an ongoing epidemic caused by a new virus? Amid the first wave of COVID‐19 in China, we conducted an online diary study, asking each of over 400 participants to predict the remaining duration of the epidemic, once per day for 14 days. Participants’ predictions reflected a reasonable use of publicly available information but were meanwhile biased, subject to the influence of negative affect and future time perspectives. Computational modeling revealed that participants neither relied on prior distributions of epidemic durations as in inferring everyday statistics, nor on mechanistic simulations of epidemic dynamics as in computing intuitive physics. Instead, with minimal experience, participants’ predictions were best explained by similarity‐based generalization of the temporal pattern of epidemic statistics. In two control experiments, we further confirmed that such cognitive algorithm is not specific to the epidemic scenario and that minimal and rich experience do lead to different prediction behaviors for the same observations. We conclude that people generalize patterns in recent history to predict the future under minimal experience.