bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long Covid: A call for global action
Authors: Loreche Arianna Maever , Pepito Veincent Christian F. , Dayrit Manuel M. 
Published: February 2023

AbstractThe COVID‐19 pandemic has resulted in another global health crisis with millions of individuals with Long Covid experiencing disability, worse health‐related quality of life, and productivity and income losses. Despite its impact on population health outcomes, health systems, and the economy, there remains a need for a global consensus on its standard definition, diagnostic approaches, and treatment plans to manage symptoms. In many low‐ and middle‐income countries (LMICs), there are limited published estimates on Long Covid, limited studies on its diagnostics and therapeutics, and limited media and news coverage. We advocate for a global action plan and necessary investments on Long Covid research and treatment, meaningful involvement of patients and cooperation between high‐income countries and LMICs, stronger and more effective public health communication surrounding the risks of Long Covid, and support toward financial risk protection as advocated by Universal Health Care.
Developing a “Sponge Catchment Management Plan (SCMP)” framework at the catchment scale: The case of Guiyang, SW China
Authors: Qi Yunfei , Chan Faith Ka Shun , Feng Meili , Griffiths James , Hutchins Michael , O'Donnell Emily , Thorne Colin , Liu Lingyun , Zhang Chunguang , Li Xinan 
Published: February 2023

AbstractCatchment floods are more challenging due to intensive urbanization and climate change. Enlightened by the Low Impact Development (LID), China initiated the Sponge City Program (SCP) to transform Urban Flood Management (UFM) to be more environmentally friendly in 2013. The China National Government (CNG) has subsidized municipal SCP facilities to enhance urban flood resilience while delivering multiple co‐benefits for urban ecosystems and social well‐being. Recent floods at Schleiden (Germany), Arizona State (USA), and Zhengzhou (China) in 2021 reflected the necessity of Catchment Flood Management (CFM) to cover the whole catchment scale. The SCP, designed to handle small‐scale urban pluvial floods, has brought concerns when facing larger‐scale fluvial floods after the Zhengzhou 2021 flood. Indeed, catchment‐scale Natural Flood Management (NFM) can manage fluvial floods while improving flood adaptations sustainably from upstream to downstream reaches. This research develops a new framework named the Sponge Catchment Management Plan (SCMP), including structural and Nonstructural elements. On the structural side, the SCMP framework integrates NFM with the SCP and Grey Engineering (GE) for reducing the fluvial flood discharge peaks in the whole‐catchment scale. On the nonstructural side, the SCMP encourages collaborative governance, revising technical standards, and improving “bottom‐up” participation. This research used Semi‐Structured Interviews (SSIs) and a Focus Group Approach (FGA) to explore 62 professional and Nonprofessional stakeholders’ perspectives on the SCMP framework. Some professional respondents did not know much about the NFM and were worried about the effectiveness of this practice. But most interviewees supported the SCMP pilot work and shared the co‐benefits from the NFM. This case study at the SW China, Guiyang, could be a lesson to encourage other Chinese cities further implement SCP to improve catchment‐scale flood resilience.
Nurturing the marriages of urinary liquid biopsies and nano‐diagnostics for precision urinalysis of prostate cancer
Authors: Liao Caizhi , Wu Zhihao , Lin Chan , Chen Xiaofeng , Zou Yaqun , Zhao Wan , Li Xin , Huang Guangqi , Xu Baisheng , Briganti Giovanni E. , Qi Yan , Wang Xianshu , Zeng Tao , Wuethrich Alain , Zou Hongzhi 
Published: February 2023

AbstractProstate cancer remains the second‐most common cancer diagnosed in men, despite the increasingly widespread use of serum prostate‐specific antigen (PSA) screening. The controversial clinical implications and cost benefits of PSA screening have been highlighted due to its poor specificity, resulting in a high rate of overdiagnosis and underdiagnosis. Thus, the development of novel biomarkers for prostate cancer detection remains an intriguing challenge. Urine is emerging as a source for prostate cancer biomarker discovery. Currently, new urine biomarkers already outperform serum PSA in clinical diagnosis. Meanwhile, the advances in nanotechnology have provided a suite of diagnostic tools to study prostate cancer in more detail, sparking a new era of biomarker discoveries. In this review, we envision that future prostate cancer diagnosis will probably integrate multiplex nano‐diagnostic approaches to detect novel urinary biomarkers. However, challenges remain in differentiating indolent from aggressive cancers to better inform treatment decisions, and clinical translation still needs to be overcome.
Early detritivory and sedimentivory in insects based on in situ gut contents from Triassic aquatic nymphs
Authors: Peñalver Enrique , Matamales‐Andreu Rafel , Juárez‐Ruiz Josep , Nel André , Lozano Rafael Pablo , Pérez‐de la Fuente Ricardo 
Published: February 2023

AbstractThe colonization of freshwater by insects is one of the milestones in the establishment of continental ecosystems and, thus, of life on our planet. However, several key aspects of this process such as patterns of origination, early adaptations and palaeoecological relationships of the groups involved remain poorly known, namely due to the scarcity of significant assemblages. The Palaeozoic fossil record of freshwater insects is poor and unstudied in suitable detail. Here we analyse exceptionally preserved, three‐dimensional cololites (in situ gut contents) in abundant mayfly nymphs from Pedra Alta (lower Anisian, lowermost Middle Triassic; Mallorca, Spain), which probably inhabited lentic waters (pools) in a riverine ecosystem. This Konservat‐Lagerstätte shows an aquatic insect assemblage c. 2 myr older than the similar locality of Grès à Voltzia (Northern Vosges, France). Detailed morphological and elemental analysis show that the cololites are composed of the same very fine‐grained claystone as the fossil‐bearing rock. This study presents the oldest direct evidence of insect detritivory, as well as most probably that of sedimentivory. The trophic niche represented by insect sedimentivory in the early continental aquatic ecosystem of Pedra Alta is not known for the subsequent c. 240 myr of insect evolutionary history and up to the present. This lifestyle in extant insects is extremely infrequent and is known only in a few species of burrowing mayfly nymphs. Our findings illuminate the role of insects in detritus processing in relatively complex food webs shortly after the end‐Permian mass extinction event.
Theoretical and experimental investigation of the time‐dependent relaxation rates of GFRP and BFRP reinforcement bars
Authors: Hiesch Dominik , Proske Tilo , Graubner Carl‐Alexander , Bujotzek Lukas , El Ghadioui Redouan 
Published: February 2023

AbstractCracked concrete members with fiber‐reinforced polymer (FRP) reinforcement generally suffer from increased deflections compared to steel‐reinforced members due to FRP reinforcements' lower modulus of elasticity. An approach to counteract this problem can be the prestressing of the FRP reinforcement, which can significantly reduce member deflections. However, time‐dependent prestress losses occur due creep and shrinkage of the concrete and relaxation of the prestressing tendons. Within the first part of this article, mathematical approaches to determine relaxation rates from creep tests are introduced. Subsequently, short‐term and long‐term tensile tests under sustained load on glass and basalt FRP reinforcement bars are presented. Based on the experimental data and the mathematical model, relaxation rates for the investigated specimens are derived. In addition, using an approach based on logarithmic extrapolation, the relaxation rates at 1 million hours (end of service life) are calculated, and the experimentally determined residual tensile properties are evaluated.
Cost‐effectiveness of pancreas surveillance: The CDKN2A‐p16‐Leiden cohort
Authors: Ibrahim Isaura S. , Vasen Hans F. A. , Wasser Martin N. J. M. , Feshtali Shirin , Bonsing Bert A. , Morreau Hans , Inderson Akin , de Vos tot Nederveen Cappel Wouter H. , van den Hout Wilbert B. 
Published: February 2023

AbstractBackgroundCDKN2A‐p16‐Leiden mutation carriers have a high lifetime risk of developing pancreatic ductal adenocarcinoma (PDAC), with very poor survival. Surveillance may improve prognosis.ObjectiveTo assess the cost‐effectiveness of surveillance, as compared to no surveillance.MethodsIn 2000, a surveillance program was initiated at Leiden University Medical Center with annual MRI and optional endoscopic ultrasound. Data were collected on the resection rate of screen‐detected tumors and on survival. The Kaplan–Meier method and a parametric cure model were used to analyze and compare survival. Based on the surveillance and survival data from the screening program, a state‐transition model was constructed to estimate lifelong outcomes.ResultsA total of 347 mutation carriers participated in the surveillance program. PDAC was detected in 31 patients (8.9%) and the tumor could be resected in 22 patients (71.0%). Long‐term cure among patients with resected PDAC was estimated at 47.1% (p < 0.001). The surveillance program was estimated to reduce mortality from PDAC by 12.1% and increase average life expectancy by 2.10 years. Lifelong costs increased by €13,900 per patient, with a cost‐utility ratio of €14,000 per quality‐adjusted life year gained. For annual surveillance to have an acceptable cost‐effectiveness in other settings, lifetime PDAC risk needs to be 10% or higher.ConclusionThe tumor could be resected in most patients with a screen‐detected PDAC. These patients had considerably better survival and as a result annual surveillance was found to be cost‐effective.
In vitro maturation of oocytes as a laboratory approach to polycystic ovarian syndrome (PCOS): From oocyte to embryo
Authors: Rodrigues Patricia , Marques Monica , Manero Juan Aibar , Marujo Maria D. , Carvalho Maria José , Plancha Carlos E. 
Published: February 2023

AbstractPolycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age, which in some case leads to infertility. This disorder is characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Infertile PCOS women that need in vitro fertilization (IVF) have greater risk of ovarian hyperstimulation syndrome (OHSS) if conventional ovarian stimulation is used. In vitro oocyte maturation (IVM) is an alternative technique that prevents OHSS in infertile PCOS women. In the last decade, IVM protocols have improved, particularly with the development of biphasic IVM culture accounting for better pregnancy and live birth rates. This technique has been extended to other treatments like, fertility preservation, when patients have no time, or a contra‐indication for ovarian stimulation, and poor responders. In this review, we will discuss IVM as a viable option for PCOS infertile patients.This article is categorized under:
Reproductive System Diseases > Molecular and Cellular Physiology
Reproductive System Diseases > Environmental Factors
Reproductive System Diseases > Genetics/Genomics/Epigenetics
Analytical and Numerical Analysis for the Vibrational Response of Timber-Concrete Composite Floor
Authors: Liu MingYu 
Published: February 2023

AbstractThis study investigates the vibration characteristics of composite timber-concrete floor systems to provide a reliable benchmark for optimizing composite floor system designs. This paper uses the numerical and analytical methods for evaluation to support more detailed study results and to build a comprehensive model for future research. Through Strand7 and ABAQUS numerical finite element analysis, geometrical layout and beam material effects on the timber-concrete composite floor are thoroughly explored. Meanwhile, the analytical results are further compared with the analytical solution based on the Dunkerley method and AISC. Then 15 kinds of timber-concrete composite floor designs are simulated and numerically tested. It was found that the dimensions of the timber beams and their composition might affect the natural frequencies of the floors. On this basis, this paper proposes future design schemes to provide reliable suggestions for further research.
Study on Sound Insulation of Integrated Composite Wallboard Made of ALC and Rock Wool Panel
Authors: Shang Renjie , Hou Zhaoxin , Mao Zhenlong , Liang Yundong 
Published: February 2023

AbstractThe integrated composite wallboard is a new type of prefabricated building enclosure wallboard made of autoclaved aerated concrete (ALC) and rock wool panel, which can meet the thermal requirements of cold areas in China without additional insulation. The ALC of the integrated composite wallboard is divided into local four-sided supported plates by vertical and horizontal ribs, which makes the wallboard have a different sound insulation performance from the wallboard of single uniform material and the composite wallboard of double-layer lightweight plates. The authors investigate the sound insulation performance of the integrated composite wallboard and compare it with other lightweight wallboards. They have found an apparent coincidence frequency region of air-borne sound insulation, which coincides with the natural vibration frequency of the local four-sided supported panel of ALC. Such an anastomosis effect seriously affects the weighted sound reduction index Rw, which reduces the weighted sound reduction index by 6 ~ 8 dB. The sound insulation experiment of integrated composite wallboard of ALC and rock wool panel objectively reflects the adverse effects of the sandwiched wallboard structure and provides a reference for improving the sound insulation performance by structurally upgrading the integrated composite wallboard.
Monitoring and Analysis of Dam Deformation in Yuankou Reservoir
Authors: Xu Ming 
Published: February 2023

AbstractDam plays an important role in regulating the flow of water. It is the key to ensure the safe and stable operation of reservoir. Taking Yuankou Reservoir Dam as the research object, this paper monitored the horizontal displacement, settlement displacement and the internal deformation of upstream dam slope from December 15, 2006 to November 27, 2017. The results show that the horizontal deformation, settlement deformation and internal deformation of upstream dam slope are within a reasonable range. The deformation distribution and variation trend conform to the general law, and the deformation of the dam is in the normal range.
Analysis on Fatigue Crack of Orthotropic Steel Bridge Decks
Authors: Ma Rui , Dong Peng , Xv Zigang 
Published: February 2023

AbstractThrough the detection of the steel structure bridge for 7 years, the main distribution of cracks in steel box girder of steel structure bridge was presented. Through the numerical analysis of the steel box girder of steel structure bridge, the stress distribution of the diaphragms was obtained. The result of detection and the numerical analysis was compared, and showed that the cracks mainly appeared in the welding parts and the arc notch of the diaphragms. The cracks at the welding part mainly came from the welding defects. And the cracks at the arc notch of the diaphragms were due to the stress concentration.
Establishment of Community Earthquake Vulnerability Assessment System
Authors: Wang Xiao , Zhang Qi , Zhang Guowei , Dong Lihui , Zheng Qiuyu 
Published: February 2023

AbstractCommunity, as the basic unit of the city, is not only the main body of earthquake response, but also the main body of urban emergency rescue response. The earthquake disaster emergency practices show that the losses of earthquake disaster are greatly affected by emergency preparedness. Therefore, it is urgent to conduct research on earthquake risk assessment and emergency preparedness capacity assessment for communities. HAZUS and Pushover method are used to establish an earthquake vulnerability assessment model based on community buildings. The vulnerability of personnel is calculated according to the probability value, which lays the foundation for emergency assessment. Finally, taking Xinchengzi community as an example, when the earthquake intensity is VII, the following conclusions are drawn: there are expected to be two deaths and seven serious injuries and 2855 displaced people in the community. The assessment system can provide reference for the government to improve the emergency response capacity.
Sensor Fault Diagnosis Method of Bridge Monitoring System Based on FS-LSTM
Authors: Li Lili , Luo Hao , Qi He , Wang Feiyu 
Published: February 2023

AbstractAn improved long-short-term memory neural network (FS-LSTM) fault diagnosis method is proposed based on the problems of damage false alarm, data of health monitoring system incorrect caused by sensor fault in bridge structure health monitoring system. The method is verified by simulating three-span continuous beams to install several sensors and considering the five failures of one sensor, the faults such as: constant, gain, bias, gain linearity bias, and noise. At first, several pieces of white noise data are randomly generated, and each piece of white noise data is applied as a ground pulsation excitation to the structure support, and the acceleration response of the structure at the sensor location is calculated. Simultaneously, each structural response record of each sensor adds white noise with the same signal-to-noise ratio to obtain the test value of each sensor; Secondly, in order to study the generality, except for the five types of faulty sensors in sequence, one sensor is randomly selected from each of the remaining spans, to verify whether there will be a situation where an intact sensor is misdiagnosed as a faulty sensor; Finally, the FS-LSTM network is constructed through the training set to predict the acceleration data, determine the sensor fault threshold, and compare the residual sequence with the fault threshold to diagnose whether the sensor is faulty. The case research of a three-span continuous beam shows that when the above-mentioned five types of faults occur in the sensor, the proposed method can correctly determine whether the sensor is faulty, and it will not be misdiagnosed, which can be used for daily bridge health monitoring. Furthermore, it provides a new method for the maintenance of the bridge health monitoring system.
Branching fractions of B meson decays in Mesogenesis
Authors: Elor Gilly , Guerrera Alfredo Walter Mario 
Published: February 2023

Abstract
Production of the matter-antimatter asymmetry in the B-Mesogenesis mechanism is directly related to the branching fraction of seemingly baryon number violating decays of B mesons into a light Standard Model baryon and missing energy. Achieving the observed baryon asymmetry requires that the branching fraction for such decays be greater than about 10−7–10−5. Experimental searches at B Factories and Hadron Colliders target specific decay modes. Therefore, computing the exclusive branching fraction for each decay is a critical step towards testing Mesogenesis. In this work we use QCD Light Cone Sum Rules to compute the form factors and branching fractions of the various possible channels contributing to the baryon asymmetry. Using the results, we comment on implications for current and future experimental searches.
A crystal structure refinement of uralolite, Ca2Be4(PO4)3(OH)3∙5H2O, from Weinebene, Austria
Authors: Mereiter Kurt , Walter Franz 
Published: February 2023

AbstractThe crystal structure of uralolite, Ca2Be4(PO4)3(OH)3·5H2O, from the spodumene deposit of Weinebene, Carinthia, Austria, has been refined with X-ray single crystal data gathered on a CCD diffractometer. Uralolite is monoclinic, space group P21/n, a = 6.553(1), b = 16.005(3), c = 15.979(3) Å, β = 101.63(1)°, V = 1641.5(5) Å3. While previously only isotropic displacement parameters and no hydrogen atom positions were reported for uralolite, now anisotropic displacement parameters were used for non-hydrogen atoms and hydrogen atoms were located and refined yielding R1 = 0.038 for 3909 observed reflections. Uralolite is built up from corrugated layers [Be4(PO4)3(OH)3]4- parallel to (010), which contain Z-shaped groups of four BeO4 tetrahedra sharing corners via three OH groups and are further crosslinked by PO4 tetrahedra. Two Ca atoms in Ca(Ophosphate)5(H2O)2 coordination and an interstitial water molecule link these layers along [010]. The OH groups and the Ca-bonded H2O molecules are all involved in hydrogen bonds with O···O distances of 2.780(2) − 3.063(2) Å and O-H···O angles of 150(1) − 179(1)° excluding a bifurcated bond. The interstitial water molecule displays a distorted tetrahedral environment of O atoms and accepts and donates each two hydrogen bonds. The crystal structure exhibits a C2/c pseudosymmetry for the [Be4(PO4)3(OH)3]4- layers and the Ca atoms. However, the disposition of the water molecules and an asymmetric hydrogen bond pattern involving OH groups as well as H2O molecules are decisive for the lowering of the symmetry of the structure to the true space group P21/n.
Energetics during eddy shedding in the Gulf of Mexico
Authors: Yang Haiyuan , Yang Chen , Liu Yongzheng , Chen Zhaohui 
Published: February 2023

AbstractUsing the Estimating Circulation and Climate of the Ocean (ECCO) Phase II product, this study investigates the energetic characteristics during eddy shedding in the Gulf of Mexico. Based on the sea level anomaly data between 1992 and 2016, a total of 34 eddy shedding events are identified. Drawing on multiscale energy and vorticity analysis method, the eddy kinetic energy (EKE) budgets are diagnosed based on the ensemble of 34 eddy shedding events. During the stage of eddy shedding, barotropic instability (BT) dominates the energy budget. Meanwhile, energy transfers from upper layer to the deep layer by vertical pressure work (PW), which is the main source of abyssal EKE. Before eddy detachment, cyclonic eddy appears at the southeastern side of the Loop Current. Even though buoyancy forcing (BF) dominates the energy budget, BT makes considerable contribution to the generation of cyclonic eddy. Baroclinic instability (BC) shares the similar horizontal distribution with BF which accounts for 32% of the value of BC.