bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association of anemia and high neutrophil-lymphocyte ratio with decreased survival in patients with laryngeal cancer treated with radiotherapy
Authors: DELİKGÖZ SOYKUT Ela , KEMAL Yasemin , KAPLAN Serkan , KARAÇİN Cengiz , ODABAŞI Eylem , UNAL Asude , ER Zehra , AYTAÇ ARSLAN Suheyla , GUNEY Yıldız 
Published: August 2023

Aims: We aimed to examine the prognostic value of inflammatory markers such as neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and anemia on oncological outcomes in patients with laryngeal squamous cell carcinomas (LSCC) treated with radiotherapy.
Methods: 213 LSCC patients analyzed retrospectively. Inflammatory markers were established by examining blood samples taken within 7 days before treatment. Patients were categorized into two groups: low and high according to NLR, PLR, and SII threshold values. In addition, to evaluate the effect of hemoglobin (Hb) level, the threshold value of each inflammatory marker and Hb level were combined, and 3 groups were formed (3 groups for NLR, 3 groups for PLR, and 3 groups for SII). The relationship between inflammatory markers and overall survival (OS), disease-free survival (DFS), and local regional recurrence-free survival (LRRFS) was investigated.
Results: In univariate analysis, high NLR, PLR, SII, and low Hb (
Comparison of infraclavicular block and axillary block activities performed in ultrasonography coexisting in upper extremity surgery
Authors: İNCEÖZ Hansa , BAYKAL Zehra 
Published: August 2023

Aims: Infraclavicular and axillary block performed with ultrasound guidance are effective peripheral anesthesia methods applied in upper extremity surgery. We aimed to compare these methods in terms of duration of the block and action, first analgesic requirement and side effects.
Methods: This prospective, randomized study was conducted for upper extremity surgery. 100 patients were included to perform infraclavicular block (Group 1, n=51) and axillary block (Group 2, n=49) USG guided. Patients are between 19 and 85 years old. Both groups were premedicated with 0.3 mg/kg midazolam or 0.5-1 μg/kg fentanyl. Both groups were treated with a mixture of local anesthetics in a total volume of 30 mL [7.5 mL 0.5% bupivacaine (Bustesin®, 56.25 mg), 7.5 mL 2% prilocaine (Priloc®, 225 mg) and 5 mL saline] was injected. Block placement time, motor and sensory tests, postoperative 2nd, 4th, 8th, 12th. and analgesic requirement at the 24th hour, Bromage scale, Verbal Rating scale, nausea vomiting, patient satisfaction, and block adequacy data were recorded.
Results: In this study, 60% of the participants included were male and 40% were female. The systolic, diastolic and mean arterial pressures were higher in group of axillary blockade than those with blockade of infraclavicular blocks. Radial, median, ulnar and musculocutaneous nerve pin-prick test loss and loss of touch test was more frequent in infraclavicular block patients. According to the Bromage scale, the partial block was seen more frequently in patients who had a close block and a full block infraclavicular block. In patients with the axillary blockade, sedoanalgesia and general anesthesia needs after postoperative intraoperative 20 min and postoperative sedoanalgesia was needed. According to the postoperative Bromage scale; complete and close to the thumb and more frequent in infraclavicular block patients. In Postop VRS, it was observed that the patients with the axillary block group had mild, moderate, and severe pain complaints. Patient satisfaction in the postoperative period was similar in both groups.
Conclusion: There is no significant difference between these techniques regarding surgical adequacy and subjective postoperative analgesia and dysesthesia. Complete and near-complete block rates in the infraclavicular block approach are minimally higher than in the axillary block approach.
A new model for estimating in-hospital mortality in patients with pulmonary embolism: PATHOS score
Authors: ALIŞKAN Halil , KILIÇ Mazlum 
Published: August 2023

Aims: Pulmonary embolism (PE) is a major contributor to the death rate associated with cardiovascular diseases. The objective of this research is to evaluate the efficacy of the PATHOS score in predicting in-hospital mortality in patients diagnosed with pulmonary embolism (PE) in emergency departments (ED).
Methods: The data of patients who were visited in the ED of a third-level healthcare facility, and diagnosed with PE between 2022 and 2023 were analyzed. To examine the value of the PATHOS score in predicting mortality, through the use of Receiver Operating Characteristic (ROC) analysis, the Area Under the Curve (AUC) was determined.
Results: The study was completed with 111 patients. Of these patients, 52 (46.8%) were male and 59 (53.2%) were female. The mean age of the patients was 67.67±16.49. When the cut-off value of PATHOS score in identifying in-hospital mortality was >2, the sensitivity was 70.8%, the specificity was 71.3%, and the positive predictive value was 41.2% and the negative predictive value was 81.9%.
Conclusion: In this study, we concluded that the PATHOS score may be an effective tool for in-hospital mortality estimation of patients diagnosed with PE in the ED. However, this score needs further evaluation in large-scale and multicenter studies.
Dynamical Masses of 20 Asteroids Determined with Gaia DR3 Asteroid Observations
Authors: Li 李 Fan 凡 , Yuan 袁 Ye 烨 , Fu 傅 Yanning 燕宁 , Chen 陈 Jian 健 
Published: August 2023

Abstract
We combined the ground-based and Gaia Data Release 3 (DR3) asteroid observations to determine the masses of 20 asteroids with asteroid–asteroid close encounters. In order to take full advantage of the high-precision observations from Gaia, we use the Fisher information to select appropriate model parameters and the modified Encke’s equation of motion to construct a dynamical model complete at the level of observation precision. With diameters from literature, bulk densities of 20 asteroids are derived. The results indicate that the utilization of Gaia DR3 provides substantial benefits in terms of improving mass precision. Among the 20 asteroids analyzed in our study, we find that 10 asteroids achieved a mass precision better than 5%, and 15 asteroids better than 10%.
Triple Spiral Arms of a Triple Protostar System Imaged in Molecular Lines
Authors: Lee Jeong-Eun , Matsumoto Tomoaki , Kim Hyun-Jeong , Lee Seokho , Harsono Daniel , Bae Jaehan , Evans II Neal J. , Inutsuka Shu-ichiro , Choi Minho , Tatematsu Ken’ichi , Lee Jae-Joon , Jaffe Daniel 
Published: August 2023

Abstract
Most stars form in multiple-star systems. For a better understanding of their formation processes, it is important to resolve the individual protostellar components and the surrounding envelope and disk material at the earliest possible formation epoch, because the formation history can be lost in a few orbital timescales. Here we present Atacama Large Millimeter/submillimeter Array observational results of a young multiple protostellar system, IRAS 04239+2436, where three well-developed large spiral arms were detected in the shocked SO emission. Along the most conspicuous arm, the accretion streamer was also detected in the SO2 emission. The observational results are complemented by numerical magnetohydrodynamic simulations, where those large arms only appear in magnetically weakened clouds. Numerical simulations also suggest that the large triple spiral arms are the result of gravitational interactions between compact triple protostars and the turbulent infalling envelope.
L’archéologie préventive appliquée à l’architecture civile de Metz
Authors: André Sitâ , Ferraresso Ivan 
Published: August 2023

Metz fut un laboratoire de l’archéologie appliquée au bâti, en raison de l’urgence patrimoniale depuis le milieu du xixe siècle, puis grâce à l’implication et à la coordination des compétences assurées par le service régional de l’archéologie (SRA). Elle est restée un modèle presque inédit en France dans les années 1980 à 1990. Depuis 2002, les études menées par l’Inrap sur des bâtiments civils alimentent, par le biais de données fiabilisées, la recherche sur l’architecture des maisons médiévales messines ; depuis les grands ensembles patriciens jusqu’à un empochement de poutre comblé, l’échelle d’observation des vestiges est multiple. L’archéologie appliquée à l’architecture domestique est aussi une histoire du maintien, de la réutilisation et du réemploi. C’est une réflexion sur les continuités latentes des savoir-faire, des modes opératoires, des usages urbains et de leurs effets sur la ville d’aujourd’hui. Par leur étude et leur préservation in situ, les découvertes sont réhabilitées dans leur dimension devenue atemporelle, mais toujours culturelle et sans doute demain écologique. Les connaissances acquises par l’archéologie doivent être, elles aussi, réemployées localement, en constituant une banque de données, un diagramme des solutions techniques à l’attention des acteurs de la rénovation.
Archéologie des occupations amérindiennes dans l’hinterland guyanais
Authors: Gassies Éric , Mestre Mickaël 
Published: August 2023

La recherche archéologique en forêt amazonienne s’est en permanence réinventée en fonction des conditions particulières imposées par le milieu et des stratégies adoptées pour y répondre. Deux nouvelles technologies ont complètement révolutionné les modes opératoires pour la détection des sites archéologiques en forêt amazonienne : le GPS et le LiDAR. Parmi les « anomalies graphiques », les plus spectaculaires qui ressortent des traitements de données figurent les géométries des sites à fossé, dénommées localement « montagnes couronnées », vestiges d’aménagement anthropique, considérés comme extrêmement rares et qui se sont avérés relativement nombreux. L’expérience acquise à partir des vérifications opérées sur le terrain montre aussi la forte présence d’autres types d’occupation humaine qui ne présentent pas de microreliefs particuliers.
Value of microRNA 370 in acute myeloid leukemia
Authors: Helbawi Fatma M. , Baset Hesham Abd EI Raheem Abd El , Sherif Tahra , Abokrisha Mohamed Z. , Saleh Mahmoud M.G.E. , Abd-Elkader Alaa S. 
Published: August 2023

Introduction
Acute myeloid leukemia (AML) is a malignant disorder of clonal hematopoietic stem cell, characterized by the rapid proliferation of leukemic blasts leading to abnormal accumulation of immature precursors and suppression of growth and maturation of cells involved in normal hematopoiesis. Several studies have elucidated the physiological roles of microRNAs (miRNA) as key regulators of hematopoiesis. Growing evidence shows that miRNA 370 may function either as a tumor suppressor or as an oncogene in various human cancer types, implying its crucial role during tumor development and progression.

Objective
The aim was to evaluate miRNA 370 expression level in patients with AML compared with healthy control and also the diagnostic and prognostic value of miRNA 370 in AML.

Patients and methods
This study was carried out on 80 participants to evaluate the role of miRNA 370 in AML. Group I (case) included 60 patients diagnosed with AML, and group II (control) included 20 healthy individuals. Quantitation of miRNA 370 was done by real-time PCR in the peripheral blood.

Results
Patients with AML had significantly higher miRNA 370 values (1.6 ± 2.8 vs. 0.24 ± 0.11; P=0.001). miRNA 370 had a sensitivity of 73% and specificity of 65% for the discrimination between AML and normal controls (area under the curve=0.80, 95% confidence interval=0.71–0.89). There was a significant association between miRNA 370 and FAB classification (P=0.001).

Conclusion
miRNA 370 is a potential diagnostic and prognostic marker for AML.
Intradermal platelet-rich plasma for the treatment of melasma: A clinical and dermoscopic evaluation in dark skin
Authors: Rout Aradhana , Mani Siddharth , Bala Nishu 
Published: August 2023

Abstract

Background:
Melasma is a common dermatosis in both men and women showing varying degrees of success with treatment. Relapse of melasma is high in dark skin types, which necessitates the need for finding a modality of treatment, which not only treats but also prevents relapse.

Aims:
To study the effectiveness of platelet-rich plasma (PRP) in patients of melasma both clinically and dermoscopically in dark skin types.

Materials and Methods:
A prospective study of 20 female patients of Fitzpatrick skin type IV–V with mixed type of melasma and bilateral involvement of the face were enrolled for the study. PRP was injected intradermally at 4 weeks interval for three sittings, and the results were assessed clinically (by modified melasma area and severity score) and dermoscopically. Patients were counselled to ensure strict sun protection measures. Patient satisfaction was noted at baseline, 4 weeks, 8 weeks, and 12 weeks. Patients were followed up for 3 months to see for any relapse of the pigmentation. The follow-up showed no relapse of melasma in these patients.

Statistical Analysis:
Analysis of variance was used with Bonferroni correction for modified melasma area and severity score at various time interval. Subject global aesthetic improvement scale (SGAIS) and physician global esthetic improvement scale (PGAIS) were expressed in counts. P-value ≤ 0.05 was considered significant.

Results:
Modified melasma area and severity score and dermoscopic changes showed statistically significant improvement compared at the end of study in mild to severe cases. The subjective assessment was made by PGAIS. Patient satisfaction levels (assessed by SGAIS) also showed significant improvement in successive weeks of treatment. Few patients had mild redness and burning post procedure, which resolved spontaneously after few hours.

Conclusion:
From this study we concluded that PRP shows a significant improvement in melasma after 12 weeks of treatment with no relapse even after 3 months. Hence, PRP may be used not only as an adjuvant but also as a first line treatment in the view of longer sustained results when combined with strict sun protection. There is a paucity of studies showing results of PRP treatment in dark skin types, which is more resistant to treatment than lighter skin. Moreover, clinical improvement should not be the only parameter to decide on stopping treatment as chances of relapse can be higher. Dermoscopic evaluation helps in determining the changes in vasculature (telangiectasias) and pigmentation (dots and globules), which are better indicators of success of treatment.
Polydioxanone bioactive sutures—Acetyl hexapeptide-8 (Argireline): An intelligent system for controlled release in facial harmonization
Authors: Velazco de Maldonado Gladys J , Suárez-Vega Dubraska V , Miller-Kobisher Blanca , García-Guevara Víctor J 
Published: August 2023

Abstract

Introduction:
We propose a new facial lifting protocol using polydioxanone (PDO) threads embedded in acetyl hexapeptide-8 (Argireline [Arg]). We assume that Arg reinforces the effects of PDO threads, as it is a mimetic of botulinum toxin. Because the PDO suture is hydrolyzable, this assumption is analyzed by instrumental analysis.

Objective:
To demonstrate the capacity of the PDO suture as a system for the controlled release of acetyl hexapeptide-8 to apply in deep wrinkles of the upper third.

Materials and Methods:
Three segments of 1-cm long 21G PDO threads immersed in 1 mL of Arg. PDO threads were observed under an optical, electron microscope at 24, 48, and 72 h later. They were also weighed before and after being soaked in Arg, and employing ultraviolet (UV)-visible spectroscopy, the release rate of Arg from the PDO suture was measured. Finally, was insert the thread PDO-Arg following a protocol designed especially for deep static wrinkles in the upper third.

Results:
The electronic weighing revealed that the PDO thread enjoys capillarity by the peptide, doubling its weight every 24 h. UV spectra revealed that PDO thread is a well-controlled release system for Arg, allowing its sustained release for 1 h. Optical and electronic photomicrographs confirm the swelling of the PDO thread by absorbing Arg by its capillarity, but this hydrophilicity does not lead to its premature physical degradation.

Conclusions:
The PDO thread system with Arg is an intelligent bioactive system useful in facial harmonization. It recommend conduct clinical trial to verify his superior lifting effect.
Difficult venesections: An easy solution
Authors: Gupta Sanjeev , Jangra Ravi Shankar , Gupta Sunita , Khatri Meghna , Gupta Namya 
Published: August 2023

Abstract
Venesection is common procedure performed in day to day life of every doctor. Conventional vein finders available are costly and not easily available. The present paper highlights the use of makeshift vein finder.
An unusual case of papillary thyroid carcinoma presenting as Graves’ disease
Authors: Tiwari Pooja , Saikia Uma Kaimal , Baro Abhamoni , Bhuyan Ashok Krishna 
Published: August 2023

ABSTRACT
The detection of thyroid cancer in patients with Graves’ disease (GD) is rare. The prognosis of thyroid cancer in patients with concomitant GD is controversial. Here, we present a rare case of papillary thyroid carcinoma (TC) associated with GD in a 23-year-old woman who presented with goiter and thyrotoxicosis symptoms and was initially diagnosed as GD. However, she underwent further investigations in view of suspicious findings and was found to have TC. The patient was subjected to surgery after controlling thyrotoxic features with the help of antithyroid medications.
Postcolonialism Unveiled: At the Nexus of Scientific Inquiry and Political Discourse
Authors: Tempest R. 
Published: August 2023

Richard Tempest is a Professor of Slavic Languages and Literatures at the University of Illinois, Urbana-Champaign, and a former director of its Russian, East European, and Eurasian Center. He holds a BA (First Class), MA, and PhD from the University of Oxford. His interests include Russian and world history and culture, military history, and the political science of the body. Tempest is the author of “Overwriting Chaos: Aleksandr Solzhenitsyn’s Fictive Worlds” (Boston: Academic Studies Press, 2019). Currently, Tempest is researching a monograph on the politics of charisma in the twenty-ﬁrst century.The conversation was conducted by Sergey Markedonov, Editor-in-Chief of the Journal of International Analytics.
Ligadura interesfinteriana del trayecto fistuloso (LIFT). Nuestros Resultados
Authors: Colucci Alexandra 
Published: August 2023

INTRODUCCION: Existen varias técnicas para el tratamiento quirúrgico de las fístulas anales. Las diferentes técnicas quirúrgicas tienen sus diferencias propias entre sí, al igual que cada caso también es diferente, por lo que los posibles resultados pueden variar. La técnica de LIFT comienza con una pequeña incisión en el surco interesfinteriano, donde se localiza el trayecto fistuloso que atraviesa por allí. Se abre el espacio, se diseca el mismo donde se procede a la sección y ligadura mediante con hilo reabsorbible, en ambos cabos con la conservación el esfínter.
OBJETIVO: Presentar y evaluar nuestros resultados de la técnica de LIFT para del tratamiento de fístulas anales.
DISEÑO: Retrospectivo, observacional de corte transversal.
MATERIALES Y METODOS: Se realizó un estudio observacional retrospectivo desde enero de 2013 a diciembre 2020. Se incluyeron pacientes con fistulas transesfinterianas. Se realizó el seguimiento de los pacientes por consultorio hasta 7 años del postoperatorio.
RESULTADOS: Se operaron en este periodo un total de 62 pacientes. El sexo predominante fue masculino. 47 pacientes con fistulas transesfinterianas bajas y 15 altas. En todos se identificó el trayecto fistuloso realizándose ligadura de ambos cabos del trayecto interesfinteriano y se procedió a un curetaje del orificio externo. Cinco pacientes presentaron dehiscencia de los puntos en piel a nivel der la incisión del espacio interesfinteriano, que se manejó en forma conservadora y presentamos 22 recidivas en este periodo de tiempo.
CONCLUSION: La técnica de LIFT parece una alternativa eficaz y segura para el tratamiento de las fístulas transesfintericas y las complejas, ya que no altera la anatomía ni la continencia, y se pueden realizar posteriormente otras técnicas o combinar varias de ellas.
Palabras Claves: LIFT, fístulas, transesfinterianas.
Editorial
Authors: Diaz Dumont Jorge Rafael 
Published: August 2023

La Universidad Nacional Autónoma de Tayacaja Daniel Hernández Morillo, presenta el Vol. 6 Nro 1 (2023) de la Revista de Investigación Científica TAYACAJA, que es una publicación científica indexada, editada por la Vicepresidencia de Investigación y está orientada a la publicación de artículos científicos originales, en la especialidad de "Ciencias Forestales y Ciencias Agrarias", según las normas indicadas.
La Revista de Investigación Científica TAYACAJA es una publicación que cuenta con certificación ISO 9001-2015, es arbitrada y cuenta con ISSNe: 2617-9156. Está indexada a: LATINDEX (Catálogo 2.0), REDIB, CROSSREF, OCLC WORLD CAT, GOOGLE SCHOLAR, ROAD, LATIN REV, ALICIA, LA REFERENCIA, MIAR, AURA, OPEN AIRE, BASE, EZ3, ERIH PLUS. Así mismo, cada uno de los artículos publicados cuenta con DOI.

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Macro and micro components of starch in different soryz (Sorghum orysoidum) varieties
Authors: Liubych V. V. , Bezlatnia L. O. , Voitovska V. I. , Marchenko T. M. 
Published: August 2023

Purpose. To determine the content of macro and micro components of starch in different varieties of soryz.
Methods. Laboratory method for determination of the content of fat, protein, starch, fatty acids, dietary fiber, water, mineral elements; calculation method for the integral score; mathematical and statistical.
Results. It was established that the starch of different soryz varieties contained mainly carbohydrates − starch and dextrin (77.5–81.0%). It should be noted that the starch of varieties ‘Kvarts’, ‘Octan’ and ‘Tytan’ had a significantly lower content of carbohydrates. At the same time, the moisture content of the starch was 8.7–11.0%, which corresponded to DSTU 3976-2000 Dry corn starch: Specifications. The content of protein in corn starch was 2.8–4.1%, dietary fiber 2.3–2.8%, fat 1.3–2.6%, saturated fatty acids and ash 0.2–0.3%, depending on the variety. The content of polyunsaturated fatty acids was 0.02–0.04%, which was the lowest. The content of sulfur in corn starch was 60.0–62.1 mg/kg, which was the highest. The content of phosphorus and potassium was at the level of 37–59 mg/kg of starch, and the content of magnesium was 33–41 mg/kg. The content of copper in starch was the least – 0.003–0.006 mg/kg. In addition, vitamin B1 was found in the amount of 0.77–0.81 mg/kg. It should be noted that the decrease in the content of micro components of starch was reliable except for sulfur. It was established that 100 g of starch provides the daily need of the human body for vitamin B1 by 7.0–7.5%, depending on the variety of soryz. Of all mineral elements, the integral score of magnesium was 1.4–1.8%. For phosphorus, this indicator was 0.7–0.9%, iron 0.2–0.3, manganese, sulfur, calcium, potassium 0.1%, copper and sodium 0.02–0.03%.
Conclusions. Macro and micro components of corn starch vary reliably depending on the variety. Soryz starch contains carbohydrates (starch + dextrin) 77.5–81.6%, protein 2.8–4.1%, dietary fiber 2.3–2.8%, fat 1.3–2.6%, saturated fatty acids and ash 0.2–0.3, polyunsaturated fatty acids 0.02–0.04%, depending on the variety. The moisture content of starch was 8.7–11.0%. Calculations show that the consumption of 100 g of starch provides only 23.2–24.4% of the human body's daily need for carbohydrates, and 9.2–11.2% for dietary fiber. The integral score for protein is 3.0–4.4% and fat 1.4–2.7%. In addition, the content of vitamin B1 in starch is 0.77–0.82 mg/kg. Sulfur content is 60.0–62.1 mg/kg, potassium and phosphorus 37–59 mg/kg, magnesium 33–41 mg/kg, sodium 10–13 mg/kg, calcium 5–9 mg/kg, iron 0.23–0.35 mg/kg, manganese 0.075–0.090 mg/kg, copper – 0.003–0.006 mg/kg.