bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal Conduction Heating for a 125 ft Deep TCE Source—Multiple Lines of Evidence for Verification of Remedial Goals
Authors: Crownover Chad , Thomas Chris , Boulos Mark , Glass Robert , Crisp Gregory , Heron Gorm , Kennington Bruce S. , Tarmann Scott , Hidalgo Luis 
Published: May 2023

AbstractThis paper describes thermal conduction heating of a trichloroethylene (TCE) source zone within vadose zone soils consisting of glacial till at depths of 50 to 125 ft below an active manufacturing facility. The performance objectives and metrics used to determine remediation success are presented. Access limitations inside the facility prevented traditional spatial soil confirmation sampling, which made performance assessment a unique challenge. Instead, the project team developed an approach utilizing multiple lines of evidence to document remedy completeness. These lines of evidence included achievement of target temperatures within the treatment volume, demonstration of asymptotic vapor concentrations extracted from the treatment volume, achieving modeled energy input goals, and verifying TCE concentrations in post‐treatment soil samples collected at the few accessible locations within the operational facility. The treatment volume was divided into three discrete treatment areas or heating groups, each constructed and heated independently in order to meet an aggressive project schedule. Additionally, each line of evidence was required to be met in each group. After approximately 283 days of heating, temperatures exceeded 90 °C at 95% of the temperature monitoring points, TCE levels had diminished to asymptotic levels in the recovered vapors, and mass removal rates from the treatment volume declined to minimal levels. Confirmatory soil sample results indicated that average TCE concentrations achieved were more than an order of magnitude below the remedial goal of 1 mg/kg.
Efficacy and safety of non‐vitamin K antagonist oral anticoagulants in patients (≥80 years of age) with atrial fibrillation: systematic review and meta‐analysis
Authors: Kang Fengguang , Su Lijun , Fan Shuke , Lv Lifen , Luo Biru 
Published: May 2023

AbstractFindings of prior studies about the efficacy and safety of non‐vitamin K antagonist oral anticoagulants (NOACs) in patients (≥80 years of age) with atrial fibrillation (AF) are controversial. So we performed a meta‐analysis to evaluate the efficacy and safety of NOACs versus vitamin K antagonists (VKAs) in patients (≥80 years of age) with AF. A systematic review of PubMed, Cochrane, Embase, Web of Science and Chinese BioMedical databases was conducted until 1 October 2022. Studies reporting the effects and safety of NOACs versus warfarin in patients (≥80 years of age) with AF were included. Two authors independently performed study selection and data extraction. Discrepancies were resolved by consensus or through an independent third reviewer. Data were synthesised according to the Preferred Reporting Items for Systematic Reviews guidelines. We identified 15 studies providing data of 70 446 participants (≥80 years of age) suffering from AF. According to the meta‐analysis (odds ratio (OR) (95% confidence interval, CI)), NOACs conferred better efficacy profile than VKAs in stroke and systemic embolism (0.8 (0.73–0.88)) and all‐cause mortality (0.61 (0.57–0.65)). Otherwise, NOACs conferred a better safety profile than VKAs in major bleeding (0.76 (0.70–0.83)) and intracranial haemorrhage (ICH; 0.57 (0.47–0.68)). In conclusion, for patients (≥80 years of age) with AF, the risks of stroke and systemic embolism, all‐cause mortality, were lower in NOACs compared to warfarin. The risks of major bleeding and ICH were also lower in NOACs compared to warfarin. NOACs showed better efficacy and safety than warfarin.
Hacking Directional Dependency in Research Design for EU Studies
Authors: Exadaktylos Theofanis , Lynggaard Kennet 
Published: May 2023

AbstractEU studies extend into political science, political theory, public and foreign policy analysis, and international relations. The field's diversity speaks to different ontological, epistemological and methodological traditions and research practices. How the EU is conceived as a political reality and entity (ontology) tends to shape how researchers substantiate knowledge production about EU affairs (epistemology) and the way they uncover this knowledge (methodology), alongside choosing research methods and data. We argue that a ‘directional dependency’ exists between research ontology, epistemology, methodology and design. Using a meta‐analysis, we review EU politics research, mapping out directional dependencies in research design; how the paths operate; and deviations from those paths. We explore damaging effects of the research design process, evaluating how much this trap informs research in principle or in practice. We find that while in‐principle directional traps exist, research can be trapped to in‐practice dependencies, limiting the scope of innovation in the field.
A new species of the conger eel genus Macrocephenchelys from deep waters of the Arabian Sea
Authors: Kodeeswaran Paramasivam , Smith David. G. , Ajith Kumar Thipramalai Thangappan Pillai , Sarkar Uttam Kumar 
Published: May 2023

AbstractA new species of the genus Macrocephenchelys is described herein based on a single specimen collected from the deep‐sea trawl landing at Kalamukku fish landing centre, Kerala coast, Arabian Sea. The new species is distinguished by having a dorsal‐fin origin behind the middle of pectoral fin, a larger head, shorter trunk, larger gill opening, dorsal surface of body with dark‐brown colour and ventral surface of head and belly with numerous patches of melanophores before anus, vertebrae 14‐30‐151. The new species shares most of the characteristics with Macrocephenchelys brevirostris but differs from it by having a more anterior dorsal‐fin origin (vs. over the tip or slightly behind the pectoral‐fin tip), larger head [15.3% total length (TL) vs. 10.5%–13.9% TL, 53.2% pre‐anal length (PAL) vs. 35.8%–47.6% PAL], shorter trunk length (13.6% TL vs. 14.4%–20.6% TL, 47.3% PAL vs. 52.4%–66.2% PAL); further it shows 7.9%–8.1% genetic divergence from the sequences of M. brevirostris.
Identifying and testing the probability distribution of earthfill dam breach parameters for probabilistic dam breach modeling
Authors: da Silva Alexandre Ângelo Carmo Luiz , Eleutério Julian Cardoso 
Published: May 2023

AbstractThe main goal of this study is to identify the probability distribution of earthfill dam breach parameters using a dam failures database (3861 observations). This work looks to fill the lack of studies observed, using an extensive database instead of empirical models, plausible values, or small databases. It is, expected that this will contribute to the development of probabilistic dam breach inundation maps instead of deterministic mapping. Four parameters were selected: (i) side slope, (ii) height, (iii) width, and (iv) formation time. To identify the best‐fit distributions, a correlation analysis was performed and a comparative analysis was undertaken by groups related to dam and failure properties such as dam type, material erodibility, magnitude, failure mode, and others. These steps defined samples with 33–311 observations. The results demonstrate that dam breach parameters might be considered independent of each other and are affected by factors such as side slope by failure mode and bottom width by dam shape. The probabilistic case study indicated that deterministic dam breach models predominantly produce conservative results of breach peak outflow.
Prevalence of gastrointestinal malignancy in non‐anemic iron deficiency and significance for endoscopic screening: A Western Australian multicenter cohort study
Authors: Hodges Samantha , Attree Chloe , Picardo Sherman , Faithfull Tiffany , McElholm Adrian , Ragunath Krish 
Published: May 2023

AbstractBackground and AimThere is a paucity of evidence regarding non‐anemic iron deficiency as a predictor for colorectal cancer and therefore the indication for endoscopic evaluation. This study explores the rates of malignancy in adults with iron deficiency with and without anemia.MethodsA retrospective multicenter diagnostic cohort study was conducted across two Australian health services. All cases that underwent both esophagogastroduodenoscopy and colonoscopy between September 1, 2018, and December 31, 2019, for the investigation of iron deficiency were included, and the cohort was divided into anemic and non‐anemic arms. Multivariate binomial logistic regression was performed to establish clinical characteristics associated with neoplasia.ResultsFive hundred eighty‐four patients underwent endoscopic evaluation over a 16‐month period. There was a significantly higher rate of malignancy in the iron deficiency anemia arm as compared with those without anemia (8.76% vs 1.20%, P < 0.01). Gastrointestinal pathology to account for iron deficiency was identified in > 60% of the total cohort. The presence of anemia (odds ratio [OR] 6.87, P < 0.01) and male gender (OR 3.01, P = 0.01) were significant predictors of malignancy.ConclusionThis study demonstrates that anemic iron deficiency confers a significantly greater risk of gastrointestinal cancer compared with non‐anemic iron deficiency. Additionally, over 60% of patients had gastrointestinal pathology to account for iron deficiency overall, supporting the need to perform baseline endoscopy in patients with iron deficiency.
MaBEL1 regulates banana fruit ripening by activating cell wall and starch degradation‐related genes
Authors: Song Zunyang , Zhu Xiaoyang , Lai Xiuhua , Chen Hangcong , Wang Lihua , Yao Yulin , Chen Weixin , Li Xueping 
Published: May 2023

ABSTRACTBanana is a typical subtropical fruit, sensitive to chilling injuries and prone to softening disorder. However, the underlying regulatory mechanisms of the softening disorder caused by cold stress remain obscure. Herein, we found that BEL1‐LIKE HOMEODOMAIN transcription factor 1 (MaBEL1) and its associated proteins regulate the fruit softening and ripening process. The transcript and protein levels of MaBEL1 were up‐regulated with fruit ripening but severely repressed by the chilling stress. Moreover, the MaBEL1 protein interacted directly with the promoters of the cell wall and starch degradation‐related genes, such as MaAMY3, MaXYL32, and MaEXP‐A8. The transient overexpression of MaBEL1 alleviated fruit chilling injury and ripening disorder caused by cold stress and promoted fruit softening and ripening of “Fenjiao” banana by inducing ethylene production and starch and cell wall degradation. The accelerated ripening was also validated by the ectopic overexpression in tomatoes. Conversely, MaBEL1‐silencing aggravated the chilling injury and ripening disorder and repressed fruit softening and ripening by inhibiting ethylene production and starch and cell wall degradation. MaABI5‐like and MaEBF1, the two positive regulators of the fruit softening process, interacted with MaBEL1 to enhance the promoter activity of the starch and cell wall degradation‐related genes. Moreover, the F‐box protein MaEBF1 does not modulate the degradation of MaBEL1, which regulates the transcription of MaABI5‐like protein. Overall, we report a novel MaBEL1‐MaEBF1‐MaABI5‐like complex system that mediates the fruit softening and ripening disorder in “Fenjiao” bananas caused by cold stress.
Owner‐Occupied Housing, Inflation, and Monetary Policy
Authors: HILL ROBERT J. , STEURER MIRIAM , WALTL SOFIE R. 
Published: May 2023

AbstractOwner‐occupied housing (OOH) is currently excluded from the harmonized index of consumer prices (HICP) in Europe. Using microlevel data for Sydney and aggregated data for the United States, France, and Germany, we compare the impact of alternative treatments of OOH on measured inflation. We recommend including OOH in the HICP using a simplified version of the user‐cost method. This would improve the harmonization of the HICP, help close the credibility gap between measured inflation and public perceptions of it, and allow the ECB to lean against a housing boom without departing from its inflation target.
A Theory of Intrinsic Inflation Persistence
Authors: KUROZUMI TAKUSHI , ZANDWEGHE WILLEM VAN 
Published: May 2023

AbstractWe propose a novel theory of intrinsic inflation persistence by introducing trend inflation and Kimball (1995)‐type aggregators of individual differentiated goods and labor in a model with staggered price‐ and wage‐setting. Under nonzero trend inflation, the non‐CES (constant elasticity of substitution) aggregator of goods and staggered price‐setting give rise to a variable real marginal cost of goods aggregation, which becomes a driver of inflation. This marginal cost consists of an aggregate of the goods' relative prices, which depends on past inflation, thereby generating intrinsic inertia in inflation. Likewise, the non‐CES aggregator of labor and staggered wage‐setting lead to intrinsic inertia in wage inflation, which enhances the persistence of price inflation. With the theory we show that inflation exhibits a persistent, hump‐shaped response to monetary policy shocks. We also demonstrate that lower trend inflation reduces inflation persistence and that a credible disinflation leads to a gradual decline in inflation and a fall in output.
Pseudo‐pseudo Meigs syndrome in systemic lupus erythematosus misdiagnosed as pseudo‐Meigs' syndrome: A case report
Authors: He Jiaqi , Li Jinke , Fan Bao , Yan Liya , Ouyang Ling 
Published: May 2023

AbstractSymptoms of pelvic masses, elevated serum CA125 levels, massive ascites, and pleural effusion in female patients are usually associated with malignancy. Some benign ovarian tumors or other nonmalignant tumors may also produce similar symptoms, called Meigs syndrome or pseudo‐Meigs' syndrome, which should be one of the differential diagnoses. However, there is an extremely rare form of SLE called pseudo‐pseudo Meigs syndrome (PPMS), which may also present with the above symptoms, but is not associated with any of the tumors. In this paper, we report a case of a 47‐year‐old woman who presented with abdominal distention. The patient was found to have elevated serum CA125 levels to 182.9 U/mL before the operation. Her PET‐CT suggested a large heterogeneous mass in the pelvis measuring 8.2 × 5.8 cm with a large amount of ascites. She was initially diagnosed with ovarian cancer and underwent exploratory laparotomy. Pathology of the surgical specimen revealed a uterine leiomyoma. Two months after discharge, the patient's ascites reappeared along with recurrent intestinal obstruction. After ascites and serological tests, she was eventually diagnosed with systemic lupus erythematosus and received systemic hormonal therapy.
The relationship between mental health, sleep quality and the immunogenicity of COVID‐19 vaccinations
Authors: Wagenhäuser Isabell , Reusch Julia , Gabel Alexander , Mees Juliane , Nyawale Helmut , Frey Anna , Lâm Thiên‐Trí , Schubert‐Unkmeir Alexandra , Dölken Lars , Kurzai Oliver , Frantz Stefan , Petri Nils , Krone Manuel , Krone Lukas B. 
Published: May 2023

SummarySleep modulates the immune response, and sleep loss can reduce vaccine immunogenicity; vice versa, immune responses impact sleep. We aimed to investigate the influence of mental health and sleep quality on the immunogenicity of COVID‐19 vaccinations and, conversely, of COVID‐19 vaccinations on sleep quality. The prospective CoVacSer study monitored mental health, sleep quality and Anti‐SARS‐CoV‐2‐Spike IgG titres in a cohort of 1082 healthcare workers from 29 September 2021 to 19 December 2022. Questionnaires and blood samples were collected before, 14 days, and 3 months after the third COVID‐19 vaccination, as well as in 154 participants before and 14 days after the fourth COVID‐19 vaccination. Healthcare workers with psychiatric disorders had slightly lower Anti‐SARS‐CoV‐2‐Spike IgG levels before the third COVID‐19 vaccination. However, this effect was mediated by higher median age and body mass index in this subgroup. Antibody titres following the third and fourth COVID‐19 vaccinations (“booster vaccinations”) were not significantly different between subgroups with and without psychiatric disorders. Sleep quality did not affect the humoral immunogenicity of the COVID‐19 vaccinations. Moreover, the COVID‐19 vaccinations did not impact self‐reported sleep quality. Our data suggest that in a working population neither mental health nor sleep quality relevantly impact the immunogenicity of COVID‐19 vaccinations, and that COVID‐19 vaccinations do not cause a sustained deterioration of sleep, suggesting that they are not a precipitating factor for insomnia. The findings from this large‐scale real‐life cohort study will inform clinical practice regarding the recommendation of COVID‐19 booster vaccinations for individuals with mental health and sleep problems.
A “good fit”: Client sorting among nonprofit, private, and pro bono immigration attorneys
Authors: Yu Lilly 
Published: May 2023

AbstractExisting scholarship finds that having an attorney in immigration legal proceedings increases the chances of a favorable outcome. This work, however, often acknowledges that the representation effect is underexplained: selection may explain outcomes, and variation among attorneys is difficult to assess. Through 103 interviews with attorneys who practice immigration law in three organizational environments (nonprofit legal services, private firms, and corporate law firm pro bono programs) in two East Coast areas, this paper argues that attorneys' sorting of clients between different types of legal organizations helps explain the representation effect. Attorneys define what type of case is a “good fit” for their representation, selecting cases they think they can help increase the probability of a favorable outcome. However, what they define as a “good fit” varies by attorneys' practice environments, and centers not only on the facts or characteristics of a client and their case, but also attorneys' organizational constraints. By documenting the central role of practice environment variation and its organizational constraints on attorneys' case selection, this paper helps explain the representation effect and its implications for increasing vulnerable immigrants' access to legal representation in the United States.
Attitudes, beliefs and social norms regarding infant and young child feeding among Nigerian mothers, fathers and grandmothers across time
Authors: Schnefke Courtney H. , Flax Valerie L. , Ubanmhen Fred , Alayon Silvia , Bose Sujata , Daniel Obinna , Grimes Kathryn E. L. , Allotey Diana , Seiger Emily R. , Arije Olujide 
Published: May 2023

AbstractInfant and young child feeding (IYCF) interventions in low‐resource countries mainly target pregnant women and mothers of young children; however, fathers and grandmothers also influence IYCF practices. We conducted focus group discussions with mothers, fathers and grandmothers of young children across three time points in areas where an IYCF social and behaviour change intervention was implemented in Nigeria to explore differences by participant type and shifts over time in attitudes, beliefs and social norms related to breastfeeding and dietary diversity (DD). Overall, across time points, we found more discrepancies in attitudes, beliefs and social norms for early initiation of breastfeeding (EIBF) and exclusive breastfeeding (EBF) among different participant types than for DD. Although most participants agreed EIBF and EBF are good practices, mothers believed this more strongly than fathers and grandmothers; however, at endline, a shift towards acceptance of EIBF and EBF appeared among fathers and grandmothers. Across time points, all participant types acknowledged the nutritional and health benefits of green leafy vegetables and animal‐source foods but described various barriers to feeding them to children. Across time points, all participant types also highlighted the importance of health workers and antenatal visits as important sources of IYCF knowledge and facilitators to following recommended practices. Insights from this study highlight the importance of including key influencers of IYCF practices in qualitative research.
The Negotiated Desecuritization Of Turkey in Saudi Foreign Policy
Authors: El Berni Hazal Muslu 
Published: May 2023

AbstractSaudi‐Turkey relations hit one of their lowest points due to the Arab uprisings and the regional shock of the Gulf crisis. The tension resulted from, and in turn exacerbated, a process of securitization of Saudi discourse, whereby officials labeled Turkey as a threat. But after three and a half years of the Gulf crisis, the Al‐Ula accords allowed reconciliation among the regional states and opened the way for the construction of new understandings based on diplomacy, tolerance of differences on regional and domestic security, and respect of sovereignty. This spurred Saudi policy makers to de‐securitize their discourse concerning Turkey—that is, to talk of it not as a threat, but as a potential partner. This process continues to develop gradually through cooperation on economics and investment, but it has required time to re‐establish confidence among Saudi decision makers. This article analyzes the discourses of Saudi leaders and policy makers and shows how they affected Saudi Arabia's relations with Turkey, both negatively and positively.
Chronic kidney disease awareness and its determinants in middle‐aged and older Japanese adults: Observations from a 5‐year follow‐up of the Uonuma cohort study
Authors: Kabasawa Keiko , Ito Yumi , Iino Noriaki , Nakamura Kazutoshi , Sawada Norie , Tsugane Shoichiro , Tanaka Junta , Narita Ichiei 
Published: May 2023

AbstractAimDespite global efforts in public health campaigns concerning chronic kidney disease (CKD), awareness of the condition remains low. We evaluated CKD awareness and related factors to identify an effective way to raise awareness.MethodsThis study assessed laboratory‐confirmed CKD and self‐reported CKD using a population‐based cohort (baseline from 2012 to 2014, age ≥40 years) in Niigata, Japan. Self‐reported CKD was obtained at a 5‐year follow‐up survey and laboratory‐confirmed CKD was diagnosed when an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 or dipstick urinary protein ≥1+ was observed in at least two health check‐ups during the 5‐year period. CKD awareness was defined as a match between laboratory‐confirmed and self‐reported CKD. The association between characteristics and CKD awareness was tested by multivariable logistic regression analysis with adjustment for eGFR and other potential confounders.ResultsThe analytic population comprised 7472 individuals (mean age, 65.6 years old, 51.2% women) and 19.4% with laboratory‐confirmed CKD. The sensitivity and specificity of the survey question concerning self‐reported CKD were 12.4% and 98.2%, respectively. Among the participants with laboratory‐confirmed CKD, significant factors associated with CKD awareness were male sex (adjusted odds ratio [95% confidence interval], 1.81 [1.27, 2.59]), a history of urinary tract stone (1.86 [1.06, 3.26]), age (0.97 [0.95, 0.99]), and married status (0.66 [0.44, 0.99]).ConclusionOur findings suggest that known lifestyle‐related diseases that could cause CKD are not associated with CKD awareness independently of kidney function and that a sex‐dependent approach may help to raise CKD awareness in community‐dwelling Japanese adults.