bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of contact with the baby following stillbirth on parental mental health and well‐being: A systematic review and meta‐analysis
Authors: Sun Shiwen , Qian Jialu , Wang Fang , Tian Yanping , Sun Yaping , Zheng Qiong , Yu Xiaoyan 
Published: March 2023

AbstractAimThis study aims to identify and synthesize available research reporting parental mental health outcomes related to contact with a stillborn baby.BackgroundStillbirth is devastating events for parents. The effects of contact with the stillborn baby on parental mental health are uncertain.MethodsThis was a systematic review and meta‐analysis carried out by searching six international electronic databases including PubMed, EMBASE, Cochrane, Web of Science, PsycINFO and CNKI databases from inception to 15 January 2023. Review Manager software was used for data analysis.ResultsTen studies were included (n = 3974). Contact with a stillborn baby increased the risks of anxiety, depression and post‐traumatic stress disorder in the short term and increased the risks of anxiety and post‐traumatic stress disorder in the long term. Parents who had contact with a stillborn baby were more satisfied with their decision. Subgroup analysis showed that seeing a stillborn baby had no significant effect on anxiety or depression, but holding a stillborn baby increased the risks of anxiety.ConclusionsCaregivers should respect the parents' decision on whether to have contact with the stillborn baby and provide parents with continuous information, emotional and behavioural support after they have contact with stillborn babies.
Enhanced broadband NIR emission in glass–ceramic fibers containing Nd3+/Yb3+ co‐doped YCa4O(BO3)3 disordered nanocrystal
Authors: Zhao Yajing , Tang Guowu , Xiong Puxian , Chen Qianyi , Sun Yongsheng , Wang Zhiduo , Chen Dongdan , Yang Zhongmin 
Published: March 2023

AbstractDemands are increasing for ultrashort pulse laser in industrial applications, where the gain bandwidth of most optical fiber material is not wide enough, and developing a wide bandwidth gain medium is challenging. Glass–ceramic fibers containing Nd3+/Yb3+ co‐doped YCa4O(BO3)3 nanocrystals were fabricated by the molten core method and successive heat treatment. After a careful heat treatment, Nd3+/Yb3+ co‐doped YCa4O(BO3)3 nanocrystals were precipitated in the fiber core. Enhanced broadband near‐infrared (NIR) emission from 850 to 1150 nm (bandwidth: ∼252 nm) was obtained in the glass–ceramic fiber compared to that of precursor fiber. These results suggest that the Nd3+/Yb3+ glass–ceramic fibers are promising for broadband NIR optical amplifications and lasers.
Herodotools: An R package to integrate macroevolution, biogeography and community ecology
Authors: Nakamura Gabriel , Rodrigues Arthur V. , Luza André Luís , Maestri Renan , Debastiani Vanderlei , Duarte Leandro 
Published: March 2023

AbstractAimSpeciation, extinction and historical dispersal are the ultimate factors generating and maintaining biodiversity. However, methods of macroevolution used to detect historical processes usually ignore the variation of macroevolutionary processes at scales finer than entire regions. Likewise, biogeography and community ecology often ignore deep‐time evolutionary processes. To overcome this problem, it is necessary to integrate data from ancestral state reconstructions, current species distributions and biogeographical regionalization. Herodotools is an R package designed to perform this integration.LocationGlobal application, with an example from Neotropics.Major taxa studiedAny taxa, with an example from small rodents (genus Akodon and subfamily Sigmodontinae).MethodsHerodotools streamline analyses of historical biogeography, including regionalization, calculation of assemblage age, lineage in situ diversification and community phylogenetic metrics, merging species occurrence with macroevolutionary methods of ancestral area and trait reconstruction. The main functions of our R package are presented with toy examples and by analysing the historical biogeography of small rodent assemblages in the Neotropics.ResultsOur package can integrate methods from biogeography, macroevolution and community ecology, allowing us to downscale the effects of historical processes and calculate important historical variables (e.g., age of assemblages, in situ diversification, phylogenetic regionalization, phylogenetic transition zones, metrics of trait macroevolutionary dynamics and new metrics of phylogenetic diversity and endemism) in different scales, from entire regions to communities of co‐occurrent species.Main ConclusionsHerodotools is the first platform to streamline the analysis of historical biogeography, enabling a better understanding of historical processes at different levels of organization, from local assemblages to entire biogeographical regions and incorporating macroevolutionary models in commonly used community phylogenetic metrics. This integration bridges the gap between macroevolutionary, biogeography and community ecology methods.
Flood vulnerability and risk assessment of historic urban areas: Vulnerability evaluation, derivation of depth‐damage curves and cost–benefit analysis of flood adaptation measures applied to the historic city centre of Tomar, Portugal
Authors: Davis Lucy , Larionova Tatiana , Patel Dhairya , Tse Demiana , Baquedano Juliá Pilar , Pinto Santos Pedro , Ferreira Tiago Miguel 
Published: March 2023

AbstractAround 45% of natural hazards reported worldwide are related to floods, and current indications show that exposure to floods and inherent losses will keep escalating. Historic centres are particularly vulnerable in this context due to the structural and material characteristics of the buildings and because they embrace social and cultural values that must be safeguarded. This article aims to contribute to this research area by presenting and discussing the application of an index‐based methodology specifically tailored to assess flood risk in historic urban centres. The historic city centre of Tomar, Portugal, an area that encompasses over 500 buildings and has a rich history of floods, is used here as a case study. Vulnerability data resulting from the application of the vulnerability assessment approach are then combined with flood hazard—that is, water velocity and depth obtained from flood peaks estimated for 20‐ and 100‐year periods of return—and used to identify the buildings at risk. Finally, a set of depth‐damage curves is derived and used here to carry out a cost–benefit analysis for different flood adaptation measures.
Role of oral iron supplementation for anemia secondary to acute nonvariceal upper gastrointestinal bleeding: a randomized controlled trial
Authors: Chang Arunchai , Rugivarodom Manus , Pungpipattrakul Nuttanit , Akarapatima Keerati , Suwanno Komsai , Rattanasupar Attapon , Ovartlarnporn Bancha , Prachayakul Varayu 
Published: March 2023

AbstractBackground and AimAlthough acute upper gastrointestinal bleeding (UGIB) can lead to anemia, evidence regarding the effects of oral iron supplementation on UGIB‐induced anemia following discharge remains lacking. The present study aimed to investigate the effects of oral iron supplementation on hemoglobin response and iron storage in patients with anemia secondary to nonvariceal UGIB.MethodsThis randomized controlled trial included 151 patients with nonvariceal UGIB who had anemia at discharge. Patients were assigned to a 1:1 block in which they were either administered 6 weeks of 600 mg/d oral ferrous fumarate (treatment group,n = 77) or treated without iron supplementation (control group,n = 74). The primary outcome was composite hemoglobin response (hemoglobin elevation greater than 2 g/dL or no anemia at the end of treatment [EOT]).ResultsThe proportion of patients achieving composite hemoglobin response was greater in the treatment group than in the control group (72.7%vs45.9%; adjusted risk ratio [RR], 2.980;P = 0.004). At EOT, the percentage change in the hemoglobin level (34.2 ± 24.8%vs19.4 ± 19.9%; adjusted coefficient, 11.543;P < 0.001) was significantly higher in the treatment group than in the control group; however, the proportions of patients with a serum ferritin level <30 μg/L and a transferrin saturation <16% were lower in the treatment group (allP < 0.05). No significant differences in treatment‐associated adverse effects and adherence rates were observed between the groups.ConclusionOral iron supplementation exerts beneficial effects on anemia and iron storage following nonvariceal UGIB without significantly impacting rates of adverse effects or adherence.
Serum brain‐derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case–control study
Authors: Dawoud N. M. , Rajab A. Z. , El‐Hefnawy S. M. , El‐Bayoumy A. M. , Salem A. M. , Seleit I. 
Published: March 2023

AbstractBackgroundDepression is a common psychiatric comorbidity among chronic dermatology patients. There is extreme lacking in the research studying biomarkers responsible for it. Both brain‐derived neurotrophic factor (BDNF) and vitamin D have a significant role in the development of depression.AimTo assess BDNF and vitamin D serum levels in different clinical verities of alopecia areata (AA) and vitiligo patients, correlating them with depression prevalence and quality of life.MethodsIn all, 30 AA patients, 30 vitiligo patients, and 30 healthy volunteers were included. Both alopecia and vitiligo severity and activity were evaluated using the suitable clinical scores. Depression was assessed using Beck depression inventory (BDI) scale and quality of life was recorded using Dermatology Life Quality Index (DLQI). Both serum BDNF and vitamin D levels were investigated using ELISA.ResultsIn both alopecia and vitiligo patients, serum BDNF and serum vitamin D were significantly lower compared to controls (p = 0.001 for both). Both were associated and negatively correlated with BDI and DLQI. Regarding alopecia, they showed a significant decline in more sever disease and with longer disease duration. However, in vitiligo, BDNF (p = 0.001) and vitamin D (p = 0.03) correlated negatively with disease activity, but not with disease severity. Serum BDNF and vitamin D correlated positively with each other (p = 0.001) in both AA and vitiligo cases.ConclusionThe inverse association of both serum BDNF and vitamin D with depression, and the positive correlation noted between their serum levels, may indicate a potential combined effect of these two players on development of depression and its negative health‐related outcomes.
Time to first dose of antibiotics in febrile neonates
Authors: Rawcliffe Nicholas , Elder Dawn , Dobinson Hazel 
Published: March 2023

AimTo assess whether febrile neonates from the community received their first dose of intravenous antibiotics within 1 h from time of arrival, as per the regional paediatric sepsis pathway, at a tertiary combined adult/child emergency department in New Zealand.MethodRetrospective data were collected from January 2018 to December 2019 with 28 patients included.ResultsMean time to first antibiotic dose for all neonates and those with serious bacterial infection was 3 h 20 min and 2 h 53 min respectively. No case used the paediatric sepsis pathway. A pathogen was identified in 19/28 (67%) neonates and 16/28 (57%) had clinical signs of shock.ConclusionThis study adds to Australasian data on community neonatal sepsis. Antibiotic administration was delayed for neonates with serious bacterial infection, clinical signs of shock and raised lactate. The reasons for delay are examined, with a number of potential areas for improvement identified.
Adolescent health and well‐being in sub‐Saharan Africa: Strengthening knowledge base and research capacity through a collaborative multi‐country school‐based study
Authors: Shinde Sachin , Noor Ramadhani Abdallah , Mwanyika‐Sando Mary , Moshabela Mosa , Tadesse Amare W. , Sherfi Huda , Vandormael Alain , Young Tara , Tinkasimile Amani , Drysdale Roisin , Baernighausen Till , Sharma Deepika , Fawzi Wafaie W. 
Published: March 2023

AbstractIn Sub‐Saharan Africa (SSA), adolescents make up around one‐quarter of the population who are growing up in a rapidly urbanizing environment, with its associated risks and benefits, including impacts on health, psychosocial development, nutrition, and education. However, research on adolescents' health and well‐being in SSA is limited. The ARISE (African Research, Implementation Science and Education) Network's Adolescent Health and Nutrition Study is an exploratory, school‐based study of 4988 urban adolescents from five countries: Burkina Faso, Ethiopia, South Africa, Sudan, and Tanzania. A multistage random sampling strategy was used to select the schools and adolescents. Adolescent boys and girls aged 10–15 years were interviewed using a standardized questionnaire by trained enumerators. The questionnaire covered multiple domains including demographic and socioeconomic characteristics, water, sanitation and hygiene practices, antimicrobial resistance, physical activity, dietary behaviours, socioemotional development, educational outcomes, media use, mental health, and menstrual hygiene (only for girls). Additionally, a desk review of health and school meal policies and programs and a qualitative investigation into health and food environments in schools were conducted with students, administrators, and food vendors. In this paper, we describe the study design and questionnaire, present profiles of young adolescents who participated in the study, and share field experiences and lessons learned for future studies. We expect that this study along with other ARISE Network projects will be a first step toward understanding young people's health risks and disease burdens, identifying opportunities for interventions and improving policies, as well as developing potential research capacities on adolescent health and well‐being in the SSA region.
Metabolomic signatures distinguish extracellular vesicles from osteoclasts and odontoclasts
Authors: Rody Wellington J. , Reuter Nathan G. , Brooks Shannen E. , Hammadi Lina I. , Martin Macey L. , Cagmat Joy G. , Garrett Timothy J. , Holliday L. Shannon 
Published: March 2023

AbstractAimsPathological dental root resorption and alveolar bone loss are often detected only after irreversible damage. Biomarkers in the gingival crevicular fluid or saliva could provide a means for early detection; however, such biomarkers have proven elusive. We hypothesize that a multiomic approach might yield reliable diagnostic signatures for root resorption and alveolar bone loss. Previously, we showed that extracellular vesicles (EVs) from osteoclasts and odontoclasts differ in their protein composition. In this study, we investigated the metabolome of EVs from osteoclasts, odontoclasts and clasts (non‐resorbing clastic cells).Materials and MethodsMouse haematopoietic precursors were cultured on dentine, bone or plastic, in the presence of recombinant RANKL and CSF‐1 to trigger differentiation along the clastic line. On Day 7, the cells were fixed and the differentiation state and resorptive status of the clastic cells were confirmed. EVs were isolated from the conditioned media on Day 7 and characterized by nanoparticle tracking and electron microscopy to ensure quality. Global metabolomic profiling was performed using a Thermo Q‐Exactive Orbitrap mass spectrometer with a Dionex UHPLC and autosampler.ResultsWe identified 978 metabolites in clastic EVs. Of those, 79 are potential biomarkers with Variable Interdependent Parameters scores of 2 or greater. Known metabolites cytidine, isocytosine, thymine, succinate and citrulline were found at statistically higher levels in EVs from odontoclasts compared with osteoclasts.ConclusionWe conclude that numerous metabolites found in odontoclast EVs differ from those in osteoclast EVs, and thus represent potential biomarkers for root resorption and periodontal tissue destruction.
New Italian version of the Wilkins Rate of Reading Test: Materials for repeated‐measure designs in optometry and neuropsychological research
Authors: Zeri Fabrizio , Tavazzi Silvia , Punzi Marco , Miglio Federica , Evans Bruce J. W. , De Luca Maria 
Published: March 2023

AbstractPurposeTo develop a series of equivalent passages of text in Italian, according to the principles of the Wilkins Rate of Reading Test (WRRT), suitable for both clinical examination and scientific research when equivalent stimuli are needed to compare performance in repeated‐measure designs.MethodFifteen high‐frequency Italian words (matched for grammatical class and length to the English WRRT) were used to generate 15 different 10‐line meaningless passages, according to the design principles of the English WRRT. Thirty‐two healthy Italian‐speaking higher education students read the passages aloud according to a fixed randomisation schedule. Performance was recorded digitally to measure reading speed and accuracy offline. Equivalence between the passages and the practice and fatigue effects for both reading speed and accuracy were examined as well as test–retest reliability.ResultsNo significant difference in reading speed and accuracy was found between the passages. There was a significant practice effect on reading speed but not accuracy, with the first presented passage read significantly slower than the others. There was no evidence of a fatigue effect. Reading speed, the reference metric for the WRRT, showed good test–retest reliability.ConclusionsThe passages of the Italian version of the WRRT were equivalent to each other. The practice effect suggests that familiarisation with the test (i.e., reading at least one matrix of words) should be carried out before consecutive/repeated reading of different passages for experimental or clinical purposes.
Nitrogen release from different polymer‐coated urea fertilizers in soil is affected by soil properties
Authors: Sentek Valerie , Velescu Andre , Wilcke Wolfgang , Henke Catarina , Peters Nils , Welp Gerd , Amelung Wulf 
Published: March 2023

AbstractThe use of urea as nitrogen (N) fertilizer in agriculture needs to consider environmental, economic and resource conservation aspects because of low N‐use efficiency (NUE). Polymer‐coated urea (PCU) offers an effective way to improve the NUE of urea and to reduce its environmental trade‐offs. However, we lack information on the impact of climate and soil properties on N release from PCU. Therefore, this study was performed to quantify the effects of soil texture, moisture and temperature on the release kinetics of N from PCU. We designed a test system for soil incubation experiments and investigated three fertilizers with different release patterns, five topsoils, three moisture levels and two temperatures over 48 days. We analysed the concentrations of inorganic N ( and ) in the soil and estimated N release rates using the unified Richards model. Soil texture did not change the N release patterns, but release rates varied significantly among the investigated soils. Changes in soil moisture for a given soil had no effect on N release from PCU and urea when fertilizers were incorporated into the soil at conditions supportive of crop growth. Lowering soil temperatures, however, decreased N release rates from PCU by 16%–49% but only in silt loam and not in sandy loam. We conclude that PCU improves the N residence time in soil, but predictions on N release from PCU must be adapted to the prevailing environmental conditions and cannot be generalized across differently textured soils.
Keratouveitis in juvenile dogs and its presumed association with canine adenovirus infection
Authors: Joyce Hannah , Oliver James A. C. , Fricker Georgina , Weir Willie , Fleming Lorraine 
Published: March 2023

AbstractObjectiveWe hypothesized that keratouveitis still occurs despite current widespread use of Canine adenovirus (CAV)‐2 vaccinations and assessed the utility of CAV‐1 and CAV‐2 titers in elucidation of its etiopathogenesis.Animals studiedNine dogs with unexplained keratouveitis (14 eyes) and nine control dogs.ProceduresThe Animal Health Trust clinical database was searched between 2008 and 2018 to identify cases of keratouveitis. Inclusion criteria included known vaccination status, interval from vaccination to development of clinical signs and availability of CAV titers. Cases were excluded if they were older than 1 year of age, or other causative ocular pathology for corneal edema was identified. Nine age‐matched dogs without corneal edema but with CAV titers were included as controls.ResultsMean CAV‐1 and CAV‐2 titers were not statistically different between dogs with keratouveitis and controls (p = .16 and p = .76, respectively). Three cases had CAV‐1 titers >5000 and two of these cases had rising convalescence titers (greater than an 11‐fold increase) suggesting infection with wild‐type CAV‐1. The six other cases did not appear to be associated with CAV infection or vaccination.ConclusionKeratouveitis continues to occur despite the advent of CAV‐2 vaccinations. While this study found no evidence to indicate CAV‐2 vaccination causes keratouveitis, the data indicates that in a proportion of cases, contemporaneous wild‐type CAV‐1 infection is a possible cause.
Eddy Current Flow Meter Measurements in Liquid Sodium at High Temperatures
Authors: Krauter Nico , Onea Alexandru Aurelian , Gerbeth Gunter , Eckert Sven 
Published: March 2023

Abstract
We present measurement results for the flow rate of liquid sodium at temperatures up to 700 °C that were obtained with a high-temperature prototype of an immersed eddy current flow meter. The experimental campaign was conducted at the SOLTEC-2 sodium loop at KIT. The main objective of the experiments is the high-temperature qualification of the Eddy Current Flow Meter as part of the safety instrumentation of generation IV liquid metal-cooled fast reactors. There it is intended to be used for monitoring the flow rate of the coolant and to detect possible blockages of subassemblies. Due to the large liquid metal volume, the sensor has to be located close to the subassemblies, therefore measurements from outside of the vessel are not possible and an immersed sensor is required. We demonstrate the successful application of the immersed eddy current flow meter (ECFM) at such high temperatures and identify the relevant effects with impact on the sensor performance.