bluuebunny/crossref_metadata_2025_split huggingface dataset:
Museo y comunidad: reflexiones desde la gestión del santuario arqueológico de Pachacamac
Authors: Pozzi-Escot Denise 
Published: September 2023

Al ser uno de los sitios arqueológicos con mayor continuidad histórica en el territorio peruano, el santuario arqueológico de Pachacamac se ha convertido en un espacio de encuentro y aprendizaje que ofrece a sus vecinos la posibilidad de realizar una serie de actividades culturales y educativas, así como participar en diversos talleres. Integrando aproximaciones de la nueva museología y considerando importante priorizar las necesidades de las comunidades aledañas a los sitios arqueológicos que gestionamos, en este artículo caracterizamos y reflexionamos cómo hemos transformado nuestra gestión y, por ende, la relación entre la comunidad, el museo y el sitio arqueológico.
Nadando entre dos aguas: el proyecto Qhapaq Ñan - Sede Nacional (2013-2018) y la gestión del patrimonio desde el Estado
Authors: Marcone Giancarlo 
Published: September 2023

Este artículo propone que los gestores del patrimonio arqueológico que trabajamos desde el Estado peruano nos encontramos inmersos en una inherente contradicción. Por un lado, seguimos considerando que la autoridad de la gestión del patrimonio está en nosotros. Por el otro, influenciados por las propuestas poscoloniales, decoloniales y del patrimonio crítico, reclamamos una mayor participación de las personas, romper los discursos hegemónicos estatales y que el patrimonio deje de ser un vehículo de exclusión. La pregunta central es ¿Cómo manejar el patrimonio arqueológico de manera profesional, generando bienestar y significado, sin caer en su manipulación estatal o convertirlo en un vehículo de poder hegemónico y desposesión a nivel local? Con base en nuestra experiencia en el proyecto Qhapaq Ñan - Sede Nacional del Ministerio de Cultura entre los años 2013 y 2018, reflexionaremos sobre esta contradicción. Así, proponemos que no es necesario negar o esconder nuestro rol como funcionarios estatales, ni abandonar la idea de lo local y/o el énfasis en la gestión participativa, sino entender el patrimonio como un espacio público, donde los actores y sus procesos se encuentren y conversen. El rol de la gestión estatal es garantizar la participación de todos estos actores mediante la adopción de los marcos conceptuales de cocreación usado en otras disciplinas.
Modification of Lipid Profile, LDL Subfractions and other Cardiovascular Risk Markers in Hypercholesterolemic Women through the Sea Buckthorn Juice Consumption
Authors: Kopčeková Jana , Mrázová Jana , Fatrcová-Šramková Katarína , Chlebo Peter , Bihari Maroš , Gažarová Martina , Lenártová Petra , Habánová Marta , Navrátilová Alica 
Published: September 2023

The purpose of this work was to investigate whether two-months supplementation with 100% sea buckthorn juice (SBJ) would modify blood lipids, LDL subfractions and other markers of cardiovascular risk in hypercholesterolemic women. A group of 28 hypercholesterolemic non-medicated adult women with a mean age of 50.58 ± 5.76 years consumed 50 mL of 100% SBJ daily for two-months. We observed a significant reduction of body weight (BW; p &lt; 0.05), body mass index (BMI; p &lt; 0.05), body fat mass (BFM; p &lt; 0.001) and visceral fat area (VFA; p &lt; 0.001), on the contrary, a significant increase of skeletal muscle mass (SMM; p &lt; 0.05) and fat-free mass (FFM; p &lt; 0.05). Supplementation with 100% SBJ significantly increased the level of high-density lipoprotein (HDL; p &lt; 0.05), reduced the level of low-density lipoprotein (LDL; p &lt; 0.05), atherogenic LDL subfractions (LDL3–7; p &lt; 0.05) and improved LDL/HDL ratio (p &lt; 0.001). After the SBJ consumption, significant reduction of C-reactive protein (CRP; p &lt; 0.001), orosomucoid (ORM; p &lt; 0.001) and interleukin 6 (IL-6; p &lt; 0.05) were found. In conclusion, consumption of SBJ showed an indication of beneficial effects on cardiovascular risk factors in hypercholesterolemic women.
Gas Mitigation Technology Review and Impact on Production Optimization for CO2 Applications
Authors: Cox J. S. , El Mahbes R. M. , Sikes M. A. 
Published: September 2023

Abstract
Enhanced Oil Recovery (EOR) utilizing carbon dioxide (CO2) has proven to be a very effective method of increasing the production of reserves in the Permian Basin and other parts of the United States. However, this recovery method increases the volume of gas that needs to be managed, with the added complexity of a varying gas density due to changing ratios of CO2 and natural gas as the flood progresses.
In previous SPE papers, the authors explored the use of various gas avoidance technologies and how effective they were in terms of CO2 avoidance, handling, and separation. This paper will combine knowledge of multiple forms of gas handling devices with experience specific to CO2. Gas mitigation methods reviewed will include shrouded ESP systems with and without dip tubes, inverted shrouds and encapsulated ESPs with forced cooling through recirculation.
This paper examines how the systems and methods are similar, notes their main differences, and compares production impacts before and after implementation of the technology. The paper will conclude with recommendations for improvements and enhancements to achieve better results on future installations, including using a combination of technologies for CO2 EOR or wells with high gas/liquid ratios (GLRs).
Stones Gulf of Mexico Single-Phase Subsea Pump Operation Under Gas Conditions to Enhance Production
Authors: Barrios L. , Merlino A. , Brutz J. , Whitaker K. , Overstreet J. , Arkhipova K. , Rojas M. , Dowdy B. , Pisarev G. , Solvoll F. 
Published: September 2023

Abstract
In a Gulf of Mexico ultra-Deepwater field (with a water depth of 10,000 ft), high-boost single-phase centrifugal subsea pumps operation under gas conditions were used to optimize overall field production by lowering the pump suction pressure below the bubblepoint to safely operate the pumps under two-phase liquid and gas production. The subsea single-phase pump (SPP) system used in Stones Field comprises multistage centrifugal pumps for high-rate (30,000 B/D) and high-boost applications. In pump applications, multiphase flow can cause problems such as performance degradation, system inefficiency, and failures that must be considered to safely operate pumps under free gas flow.
Stones pressure/volume/temperature (PVT) fluids have a range of uncertainties, leading to bubblepoints from 900–1,200 psia. Subsea Single-phase pump has been in operation in Stones since 2019, with a minimum suction pressure operating limit of 1,200 psi. The primary objective in further decreasing the suction pressure to operate below the bubblepoint was to increase the overall production through a process that integrated risk assessment, pump performance and flowline dynamic modeling, topside considerations, operating procedures, and a management of change process to approve opportunity and move to execution.
Risk assessment and operator in-house pump expertise were key enablers to assess the feasibility of the opportunity and define the primary risks to the artificial lift system while operating below the bubblepoint. A risk/value tradeoff was performed to understand value over pump failure for the Stones overall production.
Following implementation, a detailed surveillance strategy was put in place to mitigate the primary risks associated with the pump operating with allowed free gas. Up to today a total net gain of approximately 10% is being increase in the overall Stone production operating subsea pump below bubble point at 875 psia suction pressure.
The primary technical contributions of this work are the detailed technical approach and the use of analysis and data with field operation to predict pump performance and safely operate the pumps in two-phase flow in the SPP.
AI-Based Approach for ESP Optimization
Authors: Hnot T. , Vasylyshyn B. , Struk A. , Benham D. , Meek J. , Ferrara N. 
Published: September 2023

Abstract
ESP performance and health optimization play a crucial role in maximizing oil well production and overall profitability. The selection of appropriate control set points, such as pump frequency and tubing pressure, and the intervals at which adjustments are made, significantly impact production outcomes. This paper introduces an AI-based approach for ESP optimization that operates in near real-time, allowing for dynamic set point adjustments based on varying well conditions.
A dataset comprising telemetry, production, and statistical features from 193 ESP-operated wells was utilized to train the optimization model. The dataset covers a total duration of 67,358 days, averaging approximately 349 days per well. The telemetry feature set encompasses 23 distinct values, while additional information, such as well age, peak production rates, theoretical production rates, and other pertinent factors, was incorporated to provide valuable insights into various well characteristics. By leveraging this extensive dataset and employing AI techniques, the proposed approach enables effective ESP optimization, improving production outcomes and overall well profitability.
ESP Conveyance Modelling in Higher DLS Wells
Authors: Gorden William C. , Manfoumbi Wilfried , Payette Gregory S. 
Published: September 2023

Abstract
With increasing numbers of unconventional horizontal wells on single pads and the desire to get deeper unconventional wells drilled to TD as economically as possible, higher well deviations and Dogleg Severities (DLSs) have posed challenges for Electrical Submersible Pump (ESP) conveyance. These challenges have led to situations where high bending stress during ESP conveyance has led to early ESP failure. To mitigate the potential for high bending stress during ESP conveyance, there has been: A renewed focus on drilling intermediate hole sections with low DLS, andWorkflow changes to obtain and analyze gyro surveys on wells following handover from Drilling before perf & frac operations.
Summarized in the paper is a series of short run ESP failures in the Permian Basin that led to these new workflows for A/L selection and ESP conveyance planning. The study was initiated with a review of ESP teardown reports which revealed that most failures in the study area were not linked to high ESP bending stress during conveyance, but rather to Iron Sulfide (FeS) scaling within the ESPs. Nonetheless, Software was used to analyze and quantify ESP bending stress during conveyance for historical and future wells,A FeS scale inhibitor trial was initiated by adding chemical to the frac stages for some future ESP candidate wells, andApproximately 30 high resolution (1-ft) gyro surveys were collected in 5 ½" and 7" casing and processed at 1’, 15’, 25’ and 100’ intervals. Various metrics were calculated using the data, including wellbore DLS and Effective Rigid Pass-Through Diameter to highlight the advantage of gyros over traditional low resolution MWD surveys in wells where ESPs are planned.
Field Trial Result of a New Concept of Downhole Gas Slug Mitigation in Unconventional Well
Authors: Brown D. J. , Sheth K. K. , Munoz J. 
Published: September 2023

Abstract
Conventional gas separators struggle processing and delivering liquid to the pump during a gas slug event due to extremely high concentrations of gas within the separator, as there is little to no liquid to process and deliver to the pump. A special gas separator developed for mitigating the effect of gas slugs replaced a conventional, high flow, tandem gas separator system in a slugging well. The development and initial field trial results are discussed in this paper.
An investigation of the effect of gas slugs on conventional gas separator systems, where fluid entering the separator fluctuates from 97% liquid to 97% gas with varying amounts of time, inspired the creation of a novel gas separator design. A new separator with internal reservoirs, to provide additional liquid to be processed during a gas slug event, was constructed. The prototype was installed in an unconventional well with a severe "toe up" condition creating slugging initially after production started. The inability of a conventional separator to prevent gas locking in this well motivated the operatorto allow a field trial of the new separator.
Extreme interruptions in production in the well began just below 2000psi Pump Intake Pressure (PIP) resulting in severe gas slugging, and a premature failure of the ESP string. The initial gas separator was a tandem gas separator. The operator, having been made aware of a novel separator designed with slug mitigation, suggested a field trial of the concept separator.
The second installation included a new pump (having best efficiency point (BEP) from 3500 BPD to 1750 BPD) due to well conditions and the tandem gas separator was replaced with the new gas separator, a single gas separatorwith an additional liquid reservoir concept.
The field results were very encouraging. The new separator allowed drawdown below 1200 psi PIP with no interruption in production. As the PIP approached 1100 psi the slugs grew in duration and frequency, resulting in operating thedriveinProportional Integral Derivative (PID) mode and eventually gas lock mode. The most important proof of the concept was the operator's ability to operate continually through February of 2023 to a 1000 psi drawdown and an increase of gas production of nearly 20%
Data generated from the field trial has resulted in further development of the concept, including a tandem version and increased liquid storage area for increasing slug duration.
By design, slugging is a problem in most unconventional wells. In the transition from horizontal to vertical, the flow evolves into a type of slugging flow. With the drawdown of pump intake pressure, the gas percentages increase and thereby increase the size or duration of the slugs of gas. The conceptual method of providing reserve liquid within a separator to mitigate this issue has proven successful.
ESPs in High Productivity Wells and Use of Pressure Derivatives to Understand Behavior
Authors: Dowling M. , Lemus A. 
Published: September 2023

Abstract
Operators and manufacturers of ESP equipment have generally overlooked the consequences of high productivity on the operation of Electrical Submersible Pumps (ESP's). The high productivity itself causes issues such as the difficulty to identify correct rotation when starting an ESP in a well for the first time. This issue manifests itself as a small drop in intake pressure, even at high flowrates, which can make it difficult to be certain that the pump is running in the proper rotation, even after both directions have been tried. In some cases, this ambiguity causes pumps to run for lengthy periods in the wrong direction until other symptoms, such as a rise in motor temperature suggest that the performance is not correct and reverse rotation is possibly the reason for the higher temperature rise. Hence, in this paper we will introduce the application of pressure derivatives as an approach to identify the correct rotation direction when a rotation check has been conducted and also, as a strategy to aim at identifying the correct rotation much more quickly than traditional methods. In both scenarios, pressure derivatives create a signature that unmistakably differentiates the correct from the reverse rotation, which demonstrates a sound basis for determining proper operation on start-up. Furthermore, since pressure derivatives allow calculation of flowrate in the tubing and annulus based on the rate of change of pressure, they can be used to detect events such as no-flow conditions caused by gas lock, or a closed valve on surface, or a change in productivity, for example from zone bridging and plugging/unplugging.
High well productivity can create other complex situations linked to ESP's such as what the authors call ‘negative apparent productivity’. In this situation, a high productivity index, along with a high gas-to-liquid ratio (GLR), and a large distance between the pump and the producing zone, can combine to produce a counterintuitive behaviour in intake pressure at start-up, frequency change and stop. This is the effect of a significant difference in the pressure profiles in static and flowing conditions. Likewise, in this situation, we will provide an example of an offshore well where this behaviour was observed and will explain the underlying mechanism that produces it.
Reverse engineering the control law for schooling in zebrafish using virtual reality
Authors: Li Liang , Nagy Mate , Amichay Guy , Wang Wei , Deussen Oliver , Rus Daniela , Couzin Iain 
Published: September 2023

Abstract
Revealing the evolved mechanisms that give rise to collective behavior is a central objective in the study of cellular and organismal systems1-12. In addition, understanding the algorithmic basis of social interactions in a causal and quantitative way offers an important foundation for subsequently quantifying social deficits13-16. Here, we employ immersive Virtual Reality (VR)17 to reverse-engineer the sensory-motor control of social response during schooling in a vertebrate model: juvenile zebrafish (Danio rerio). In addition to providing a highly-controlled means to understand how zebrafish translate visual input to movement decisions, networking our systems allows real fish to swim and interact together in the same virtual world. Together, this allows us to directly test models of social interactions in situ. A key feature of social response is shown to be single- and multi-target-oriented pursuit. This is based on a quasi-2D egocentric representation of the positional information of conspecifics, and is highly robust to incomplete sensory input. We demonstrate, including with a 'Turing test' for pursuit behavior, that all key features of this behavior are accounted for by individuals following a simple experimentally-derived proportional derivative control law, which we term 'BioPD'. Since target pursuit is key to effective control of autonomous vehicles, we evaluate—as a proof of principle—the potential utility of this simple evolved control law for human-engineered systems. In doing so, we find close-to-optimal performance in autonomous vehicles (terrestrial, airborne, and watercraft) pursuit, while requiring limited system-speciﬁc tuning or optimization.
Poor Sleep Quality Increases Gestational Weight Gain Rate in Pregnant People: Findings from the MADRES Study
Authors: Bastain Theresa , Naya Christine , Yang Tingyu , Vigil Mario , Chen Cindy , Chavez Thomas , Toledo-Corral Claudia , Farzan Shohreh , Habre Rima , Lerner Deborah , Lurvey Nathana , Grubbs Brendan , Dunton Genevieve , Breton Carrie , Eckel Sandrah 
Published: September 2023

Abstract

Background
Poor sleep quality is associated with weight gain in non-pregnant populations, but evidence in pregnant people is lacking. Our study examined the association between early-to-mid pregnancy sleep quality and weekly gestational weight gain (GWG) rate during mid-to-late pregnancy by pre-pregnancy body mass index (BMI).
Method
Participants were 316 pregnant participants from the Maternal and Developmental Risks from Environmental and Social Stressors (MADRES) study. During early-to-mid pregnancy, participants reported their sleep quality which was used to construct four categories: very poor, poor, good, and very good. Linear growth curve models examined the association between early-to-mid pregnancy sleep quality and weekly rate of GWG (kg/week) during mid-to-late pregnancy (> 20 weeks gestation), with a three-way cross-level interaction between gestational age, sleep quality, and pre-pregnancy BMI category. Models adjusted for ethnicity by birthplace, hypertensive disorders, perceived stress score, and physical activity level.
Results
Overall, poorer early-to-mid pregnancy sleep quality was associated with increased weekly weight gain during mid-to-late pregnancy. For example, amongst normal weight participants, mid-to-late pregnancy weight gain was, on average, 0.39 kg (95% CI: 0.29, 0.48) per week for those with very good sleep quality, 0.53 kg (95% CI: 0.44, 0.61) per week for those with poor sleep quality, and 0.54 kg (95% CI: 0.46, 0.62) per week for those with very poor sleep quality during early-to-mid pregnancy. This difference in GWG rate was statistically significantly comparing very good to poor sleep (0.14 kg/week, 95% CI: 0.01, 0.26) and very good to very poor sleep (0.15kg/week, 85% CI: 0.02, 0.27). This association between sleep quality and GWG rate did not statistically differ by pre-pregnancy BMI.
Conclusion
Our study found very poor early-to-mid pregnancy sleep quality was associated with higher mid-to-late pregnancy GWG rate. Incorporating pregnancy-specific sleep recommendations into routine obstetric care may be a critical next step in promoting healthy GWG.
Influence of isotretinoin on orthodontic tooth movement in rats: microtomographic and histomorphometric analysis
Authors: Ferreira Mayra Fernanda , Silva Cristina Antoniali , Ervolino Edilson , Costa Luy de Abreu , Santos José Ricardo Prando dos , Delbem Alberto Carlos Botazzo , de Mendonça Marcos Rogério 
Published: September 2023

Abstract

Objective
Isotretinoin, also known as 13-cis-retinoic acid, is an isomer of tretinoin, the oxidized form of Vitamin A. Orthodontic tooth movement (OTM) is the result of a cascade of inflammatory responses stimulated by a physical element that is the force generated by orthodontic appliances. Considering that there are individuals undergoing orthodontic treatment while also using isotretinoin, and that there is limited information on the effects of this combination in the literature, we are proposing this study to evaluate the influence of isotretinoin on OTM.
Materials and Methods
Thirty-five animals were used, and they were randomly divided into 7 groups, containing 5 animals in each group. Group 1: Control; Group 2: OTM for 7 days; Group 3: OTM for 14 days; Group 4: Treated with isotretinoin for 14 days; Group 5: Treated with isotretinoin for 21 days; Group 6: Treated with isotretinoin for 14 days and undergoing OTM for 7 days; Group 7: Treated with isotretinoin for 21 days and undergoing OTM for 14 days. In Groups 6 and 7, the animals were treated with isotretinoin at a dosage of 1.0mg/kg/day for 7 days before OTM and maintained during the movement period in the respective groups.
Results
There was no significant difference on microtomographic parameters [Trabecular Volume (BV/TV), Trabecular Thickness (Tb.Th), Number of Trabeculae (Tb.N) and Trabecular Separation (Tb.Sp)] and tooth displacement between groups.
Conclusion
Isotretinoin did not cause a reduction in tooth displacement during OTM when administered at a dose of 1.0mg/kg/day and isotretinoin did not change the microtomographic parameters of animals treated with isotretinoin + OTM.