bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐resolution WENO‐Z type scheme with mapped global smoothness indicator for hyperbolic conservation laws
Authors: Tang Shujiang 
Published: January 2025

AbstractTo address the shortcomings of the WENO‐Z scheme in terms of reducing accuracy at higher‐order critical points, this paper proposes a new two‐parameter global smoothing factor by introducing a sub‐stencil mapping function and develops a new WENO‐Z scheme, WENO‐ZI. With the chosen parameters and , the new scheme can achieve the desired accuracy at critical points of any order, and the resolution is enhanced as increases. Numerical results indicate that the new scheme performs optimally when and for one‐dimensional problems, and for two‐dimensional problems. The theoretical results verify the high accuracy and high‐resolution of the new WENO‐ZI scheme. Numerical experiments of the new mapping method for one‐ and two‐dimensional benchmark problems are compared with various numerical schemes. Results demonstrate that the new WENO scheme achieves higher resolution compared to other numerical methods. It satisfies the desired accuracy at critical points of arbitrary orders and can be easily extended to higher‐order schemes.
Quadratic convective slip flow of a viscous dissipative Casson C2H6O2$C_{2}H_{6}O_{2}$—Diamond nanofluid over a stretching sheet
Authors: Balamurugan R. , Chamkha Ali J. 
Published: January 2025

AbstractThe present study explores the slip flow properties of a Casson ethylene glycol ‐diamond (spherical‐shaped particle) nanofluid across a stretched sheet, taking into account the effects of viscous dissipation, nonlinear (quadratic) convection, and the presence of space‐temperature dependent heat sources. The inquiry solves the strongly complicated partial differential equation (PDE) regulating the flow dynamics using an implicit Crank‐Nicolson approach. This is essential because it helps explain how nonlinear convective dissipation affects flow and heat transfer characteristics. In particular, a critical factor is the interaction between viscous dissipation and intense nonlinear convection against the heat source. Additionally, the evaluation prioritizes higher Prandtl numbers, adding further importance to the research. Numerical simulations compared against extant literature reveal excellent agreement. Observations indicate that as Prandtl numbers and volume fractions increase, skin friction tends to rise while the Nusselt number tends to decline. However, intriguingly, at , skin friction begins to diminish, whereas while the volume fraction increases, the Nusselt number grows as well. Steady and unsteady results have been captured and discussed in detail through the graphical plots and tables.
Geopolitics and the South China Sea
Authors: Buszynski Leszek 
Published: January 2025

Abstract
This paper examines the impact of geopolitics on the South China Sea maritime dispute and it submits three propositions. First, the resolution of this dispute to achieve long-term stability is through the application of UNCLOS and the accepted norms and rules of international law. However, China rejected a UNCLOS-based resolution of this issue when it repudiated the ruling of the 2016 Arbitral Tribunal of the Law of the Sea and insisted on the validity of its historical rights to the area and the nine-dash line.
Emission Reduction from Shipping and Net-Zero Shipping: Institutional Deficiencies and the Way Forward
Authors: Tsimplis Michael 
Published: January 2025

Abstract
A relatively small number of states dominate the shipping market. There are three major shipbuilding states and four ship-recycling states. Thirty-five states owned ninety-five percentage of the deadweight tonnage with Greece, China, and Japan, owning more than 42%. The top eight ship registers have more than 5% of the global tonnage each, and collectively account for 66% of the global tonnage.
Limits of Cooperation: China’s Strategic Intent in the South China Sea and the U.S.-China Security Dilemma
Authors: Kirchberger Sarah 
Published: January 2025

Abstract
This paper argues that an underlying security dilemma between the two great powers China and the U.S. exacerbates existing conflicts of interests and impairs chances for cooperation in the South China Sea (SCS) between China and most other claimants for the foreseeable future
Kutane Ulzerationen bei Dermatomyositis
Authors: Wald Caroline , Simon Jan-Christoph , Treudler Regina 
Published: January 2025

Zusammenfassung
Eine 33-jährige Patientin mit Anti-NXP2(„nuclear matrix protein 2“)-positiver und eine 67-jährige Patientin mit TIF1-gamma(„transcription intermediary factor 1 gamma“)-positiver Dermatomyositis entwickelten unter Systemtherapie mit Azathioprin bzw. Low-dose-Methylprednisolon und zyklischer Verabreichung von intravenösen Immunglobulinen (IVIGs) schmerzhafte Ulzerationen im Gesichts- und Körperstammbereich bzw. an den Händen. In der laborchemischen Diagnostik blieb bei beiden Patientinnen der Anti-MDA5(„anti-melanoma differentiation-associated protein 5“)-Antikörperstatus negativ und die Kreatinkinase (CK) normwertig, die histopathologischen Untersuchungen erbrachten ein unspezifisches Ergebnis. Eine intensive topische Kortikosteroidtherapie der Klasse 4 und Fortführung der immunsuppressiven bzw. immunmodulierenden Therapie führten zur Abheilung der ulzerativen Hautveränderungen. Dieser Bericht soll für das seltene Auftreten kutaner Ulzerationen bei einer Anti-NXP2- bzw. Anti-TIF1-gamma-positiven Dermatomyositis sensibilisieren, da Ulzerationen mit einem schweren Krankheitsverlauf assoziiert sein können. In unseren beiden Patientenfällen handelt es sich um eine ausschließlich dermale Ausprägung ohne sonstige Komplikationen.
Präimplementierung von elektronischen Patientenberichten an Referenzzentren für Kopf-Hals-Onkologie
Authors: Dejaco Daniel , Gottfried Timo , Santer Matthias , Thurner Anna , Lehmann Jens , Riedl David , Rumpold Gerhard , Holzner Bernhard , Schmutzhard Joachim , Hofauer Benedikt 
Published: January 2025

Zusammenfassung

Hintergrund
Elektronisch erfasste Patientenberichte („electronic patient-reported outcomes“, ePRO) sind digitale, von Krebspatienten ausgefüllte Fragebögen. Trotz Hinweisen auf eine Verbesserung der klinischen Versorgung, ist die Integration von ePRO in der klinischen Kopf-Hals-Onkologie Neuland.

Ziel der Arbeit
Diese Arbeit skizziert den Implementierungsprozess für ePRO der Universitätsklinik für Hals‑, Nasen- und Ohrenheilkunde der Medizinischen Universität Innsbruck (HNO Innsbruck).

Methoden
Die Implementierung erfolgt durch eine Projektteam in einer Präimplementierungsphase (Bedarfsevaluation, Implementierungsplanung, Identifikation innerklinischer Barrieren, Prototypenentwicklung, Testung und Adaptierung sowie Anwenderschulung), Implementierungsphase (Implementierung und Anwendertraining) und Postimplementierungsphase (Qualitätskontrolle, Projektausweitung).

Ergebnisse
Das Projektteam an der HNO Innsbruck besteht aus 10 Mitgliedern, die Digitalisierungsbedarf in der Krebsnachsorge identifizierten. Eine Hybridimplementierunglösung („Computer-based Health Evaluation System“, CHES; Fa. Evaluation Software Development, ESD, Innsbruck, Österreich) wurde gewählt. ePRO („European Organization for Research and Treatment of Cancer Quality of Life Questionnaire – 30 items“, EORTC-QLQ-C30; Head and Neck Functional Integrity Scale, HNC-FIT Scale; und EORTC Head and Neck Cancer Module, EORTC H&N43) werden 12-mal über 5,5 Jahre erhoben. Insgesamt 25 Anwender bewerten den Prototypen als benutzerfreundlich (Patientensicht: 8,1 ± 1,6; 3–10; Anwendersicht: 8,6 ± 1,1; 6–10). Als Hauptvorteil wurde die schnellere Anamnese (72 %), als Hauptnachteil fehlendes Personal, Zeit und Motivation (52 %) genannt.

Schlussfolgerung
Das Feedback zum ePRO-Prototypen in der HNO Innsbruck war positiv. Die Implementierungsphase wurde im ersten Quartal 2024 gestartet. Die Zielerreichung wird in der Postimplementierungsphase im vierten Quartal 2024 evaluiert.
Tests for segregation distortion in tetraploid F1 populations
Authors: Gerard David , Thakkar Mira , Ferrão Luis Felipe V. 
Published: January 2025

Abstract

Key message:
In tetraploid F1 populations, traditional segregation distortion tests often inaccurately flag SNPs due to ignoring polyploid meiosis processes and genotype uncertainty. We develop tests that account for these factors.

Abstract:
Genotype data from tetraploid F1 populations are often collected in breeding programs for mapping and genomic selection purposes. A common quality control procedure in these groups is to compare empirical genotype frequencies against those predicted by Mendelian segregation, where SNPs detected to have segregation distortion are discarded. However, current tests for segregation distortion are insufficient in that they do not account for double reduction and preferential pairing, two meiotic processes in polyploids that naturally change gamete frequencies, leading these tests to detect segregation distortion too often. Current tests also do not account for genotype uncertainty, again leading these tests to detect segregation distortion too often. Here, we incorporate double reduction, preferential pairing, and genotype uncertainty in likelihood ratio and Bayesian tests for segregation distortion. Our methods are implemented in a user-friendly R package, . We demonstrate the superiority of our methods to those currently used in the literature on both simulations and real data.
Population pharmacokinetic model of tranexamic acid in patients who undergo cardiac surgery with cardiopulmonary bypass
Authors: Nakai Tsuyoshi , Tamura Takahiro , Miyagawa Yasuhiro , Inagaki Takayuki , Mutsuga Masato , Yamada Shigeki , Yamada Kiyofumi , Nishiwaki Kimitoshi , Mizoguchi Hiroyuki 
Published: January 2025

Abstract

Purpose
Tranexamic acid (TXA) is widely used as an antifibrinolytic drug. However, studies to determine the optimal blood concentration of TXA have produced inconsistent results. During cardiac surgery, cardiopulmonary bypass (CPB) has serious effects on drug distribution, elimination, and plasma concentration. Therefore, we aimed to establish a population pharmacokinetics model of TXA in patients undergoing cardiac surgery with CPB that considers renal function as a covariate, thereby facilitating personalized treatment.

Methods
In total, 453 TXA plasma samples were prospectively collected from 77 patients who underwent cardiac surgery with CPB. Plasma concentrations were determined by ultra-performance liquid chromatography-tandem mass spectrometry. The population pharmacokinetic model of TXA was analyzed using nonlinear mixed-effects modeling.

Results
The two-compartment–based model with combined errors was determined as the best. The final model included the effect of bodyweight and CLcr may be summarized as V
1 (L) = 12.77 × (bodyweight / 61.4)0.911, V
2 (L) = 6.857, CL1 (L/h) = 3.263 × [CLcr (L/h) / 61.0]0.752, CL2 (L/h) = 2.859.

Conclusion
Patients who undergo cardiac surgery with CPB may require an adjusted dose of TXA tailored to CPB due to lower CL1 and increased V
1. Our TXA population pharmacokinetic model may be useful for developing individualized dosing designs for TXA in patients who undergo cardiac surgery with CPB.
Efficacy and safety of olverembatinib as maintenance therapy after allogeneic hematopoietic cell transplantation in Philadelphia chromosome–positive acute lymphoblastic leukemia
Authors: Kong Jun , Zheng Feng-Mei , Yan Chen-Hua , Wang Jing-Zhi , Fu Hai-Xia , Wang Zhi-Dong , Suo Pan , Hu Guan-Hua , Lv Meng , Chen Huan , Mo Xiao-Dong , Xu Lan-Ping , Zhang Xiao-Hui , Huang Xiao-Jun , Wang Yu 
Published: January 2025

Abstract
Experience using olverembatinib as maintenance therapy in patients with Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) after allogeneic hematopoietic cell transplantation (allo-HCT) is limited. We retrospectively collected data from 26 patients with Ph+ ALL who received only olverembatinib as maintenance therapy after allo-HCT. Olverembatinib was administered as prophylaxis in 18 patients (69.2%), and preemptively in 8 patients (30.8%). The median time of olverembatinib initiation after transplantation was 2.5 months (range, 1-7.3). The median starting dose of olverembatinib was 35 mg qod (range, 15–40). The median duration of olverembatinib treatment was 12.5 months (range, 6–23). Olverembatinib maintenance treatment was discontinued in 8 patients (8/26,30%), seven stopped the drug for a long-lasting BCR-ABL1 negativity and 1 for recurrent fever associated with the drug. BCR-ABL1 turned positive in 3 patients in 2, 3 and 6 months after discontinuation. During olverembatinib treatment, three patients developed grade ≥ 3 hematologic side effects, which resolved with dose interruption or dose reduction. The median follow-up time after allo-HCT were 17.75 months (range 7–31). The hematologic relapse rate was 7.7% (2/26), with no event in the preemptive group. The 3-year probability of overall survival and relapse free survival after allo-HCT was 91.7% and 79.1%, respectively. Only one patient in prophylaxis group died of central central nervous system (CNS) relapse. Thus, our data suggest that olverembatinib is effective and safe as maintenance treatment in patients with Ph+ ALL who underwent allo-HSCT. The main adverse effect was hematologic toxicity, which was tolerated.
Informing nitrate concentration trends: estimating groundwater residence time in a karstic, multiaquifer system using anthropogenic tracers (Minnesota, USA)
Authors: Kuehner Kevin J. , Runkel Anthony C. , Barry John D. 
Published: January 2025

Abstract
Interpretation of groundwater nitrate trends in the agricultural, karstic landscape of southeastern Minnesota, USA, has been confounded by an inadequate understanding of residence time. Temporal monitoring of alachlor ethane sulfonic acid (ESA) concentrations, a transformation product of the discontinued but commonly used agricultural herbicide alachlor from the 1970s and 1980s, was used to approximate post-1953 groundwater residence times. Statewide alachlor usage patterns were compared with corresponding ESA concentration trends measured from springs and wells. Nonparametric regressions and other methods were used to quantify residence times, which were compared with the results derived from atmospheric tracers. Corroboration between the multiple, independent age tracer methods suggests groundwater mixtures from shallow (<60 m) springs have apparent residence times of one to two decades. In contrast, springs in deeper settings have residence times ranging from two to four decades. Similar methods applied to domestic wells revealed analogous results across comparable hydrogeologic conditions. Residence times for springs and wells, across all age dating methods were significantly different by geologic setting and correlated with depth. Trend analysis combined with residence time estimates implies legacy sources of contaminants, such as nitrate, have not fully migrated through aquifer systems and that concentrations in certain springs, streams, and wells with older water will continue to increase until an equilibrium has been reached with current and historical land use. These results also provide insight into the challenges of measuring water quality response to improved land-use practices using monitoring sites with mixed groundwater residence times.
Minimally invasive versus open surgery for colonic diverticular disease: a nationwide analysis of German hospital data
Authors: Kolbe E. W. , Buciunas M. , Krieg S. , Loosen S. H. , Roderburg C. , Krieg A. , Kostev K. 
Published: January 2025

Abstract

Background
This study aims to evaluate the current rates and outcomes of minimally invasive versus open surgery for colonic diverticular disease in Germany, using a nationwide dataset.

Methods
We analyzed data from 36 hospitals, encompassing approximately 1.25 million hospitalizations from 1 January 2019 to 31 December 2023. Patients aged 18 years and older with colonic diverticular disease (International Classification of Diseases, Tenth Revision (ICD-10): K57.2 and K57.3) who underwent surgical treatment were included. Surgeries were classified as open or minimally invasive (laparoscopic or robotic). Outcomes such as in-hospital mortality, complications, and length of stay were assessed using multivariable logistic and linear regression models.

Results
Out of 1670 patients who underwent surgery for colonic diverticular disease, 63.2% had perforation and abscess. The rate of minimally invasive surgery increased from 34.6% in 2019 to 52.9% in 2023 for complicated cases and from 67.8% to 86.2% for uncomplicated cases. Open surgery was associated with higher in-hospital mortality (odds ratio (OR): 7.41; 95% CI: 2.86–19.21) and complications compared with minimally invasive surgery. The length of hospital stay was significantly longer for open surgery patients, with an increase of 4.6 days for those with perforation and abscess and 5.0 days for those without.

Conclusions
Minimally invasive surgery for colonic diverticular disease is increasingly preferred in Germany, especially for uncomplicated cases. However, open surgery remains common for complicated cases, but is associated with higher mortality, more complications, and longer hospital stays.
Green finance development and its origin, motives, and barriers: an exploratory study
Authors: Hu Die , Gan Christopher 
Published: January 2025

Abstract
As global awareness of sustainability significance intensifies, green finance has become a focal point. In response to this trend, our study extensively examines the evolution of green finance, using exploratory methodologies to produce insightful observations. We perform an all-inclusive bibliometric analysis of literature regarding green finance to reveal significant trends and critical contributors to the domain. Further, we explore the historical evolution of green finance, analyzing its fundamental principles, examining the driving factors and obstacles, and forecasting future directions. We attempt to offer a clearer insight into green finance, facilitating decision-making by scholars, industry professionals, and policymakers.
Partnership Preferences in Modern Migration Societies: Religious Homophily Among Young Muslims and Christians in Germany
Authors: Heyne Stefanie , Kuhlemann Jana , Kogan Irena 
Published: January 2025

Abstract
Preferences for homogamous partnerships, not only in terms of having a partner with the same ethnicity, but one with the same religion, are an important factor in explaining low levels of interethnic partnerships in Western countries. However, previous research has rarely explicitly focused on the role of preferences for partnership formation patterns. Using data from a factorial survey experiment, which was implemented in the 9th wave of the “Children of Immigrants Longitudinal Survey in Four European Countries” among young adults in Germany (CILS4EU-DE), this study explores patterns of religious homophily in partnership preferences among young adults in Germany. It thereby specifically focuses on individuals belonging to two major religious groups: Christians and Muslims. It investigates the effects of religious denomination, religiosity, type of intimate partnership, and gender differences for religious homophily in partnership preferences. Both male and female respondents were found to prefer partners of the same religious denomination, with this effect being stronger among Muslims than Christians. Muslim respondents showed no or little disapproval of more strongly religious partners, whereas Christian respondents showed strong disapproval of more religious partners. Among Christian and male Muslim but not among female Muslim respondents, preferences for religious homophily were lower for casual partnerships than for marriage. Overall, the findings suggest that religious homophily and religion play an important part in shaping partnership choices among young Christian and Muslim adults in Germany.
From Transient Traces to Material Witnesses: an Archaeological Investigation of Contemporary Border Crossings in the Eastern Mediterranean
Authors: Jungfleisch Johannes 
Published: January 2025

Abstract
Contemporary migration from the Global South to the Global North is marked by vulnerability, violence, and injustice. These processes give rise to distinct materialities in border regions and transit countries. Although inherently mute, such traces can act as “material witnesses,” testifying to the inequities encountered along these journeys. Contemporary archaeology can apply its research methods to document and analyze these material remains, revealing past instances of injustice and violence. Drawing on fieldwork conducted in Turkey and Greece, this paper conceptualizes specific material traces of ongoing migration movements to Europe as material witnesses, shedding light on overlooked stages of migration pathways.
Optimization of a viscous-elastic damper coupling two simple oscillators based on nonlinear stochastic response
Authors: Potenza Francesco , Gattulli Vincenzo , Vasta Marcello 
Published: January 2025

Abstract
Among the techniques used to control or mitigate the structural vibrations induced by dynamic input, such as wind and earthquake, the dissipative coupling is one of the most applied, especially for its ease of implementation. Indeed, for example in large urban areas, it is common to find adjacent structures where the space between the buildings becomes smaller. To optimally select the visco-elastic features of the dissipative device to be used, the paper retraces the path followed by the previous scientific works proposing new design criteria. Such criteria are based on the nonlinear stochastic response of two simple oscillators linked by a damper whose hysteretic behavior is represented by a Bouc-Wen model. A state-space formulation of the equations of motion has been adopted to facilitate the analysis of the dynamic response. At the same time, the loading is hypothesized as a zero-mean Gaussian excitation. Consequently, the nonlinear response has been approximately evaluated by the equivalent linearized standard deviations for both displacements and accelerations. Subsequently, formulations of objective functions, based on the Minimax and Total Energy of the equivalent linearized stochastic response, have been applied to determine the optimal configurations of the coupled system. The influence of both noise power amplitude and soil typology on the designed systems has been also investigated. Suggestions related to the path to achieve pre-fixed targets (as balancing of displacements and accelerations) are provided.