bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term stability of infrabony defects treated with enamel matrix derivative alone: A retrospective two‐centre cohort study
Authors: Koronna Ilona , Schacher Beate , Dahmer Iulia , Nickles Katrin , Sonnenschein Sarah K. , Kim Ti‐Sun , Eickholz Peter , Petsos Hari 
Published: April 2023

AbstractAimTo assess the long‐term stability of attachment gain in infrabony defects (IBDs) 10 years after regenerative treatment with an enamel matrix derivative (EMD) alone.Materials and MethodsTwo centres (Frankfurt [F] and Heidelberg [HD]) invited patients for re‐examination 120 ± 12 months after regenerative therapy. Re‐examination included clinical examination (periodontal probing depths (PPD), vertical clinical attachment level (CAL), plaque index (PlI), gingival index (GI), plaque control record, gingival bleeding index and periodontal risk assessment) and review of patient charts (number of supportive periodontal care [SPC] visits).ResultsBoth centres included 52 patients (29 female; median baseline age: 52.0 years; lower/upper quartile: 45.0/58.8 years; eight smokers), each contributing one IBD. Nine teeth were lost. For the remaining 43 teeth, regenerative therapy showed significant CAL gain after 1 year (3.0; 2.0/4.4 mm; p < .001) and 10 years (3.0; 1.5/4.1 mm; p < .001) during which CAL remained stable (−0.5; −1.0/1.0 mm; p = 1.000) after an average SPC of 9 years. Mixed‐model regression analyses revealed a positive association of CAL gain from 1 to 10 years with CAL 12 months post operation (logistic: p = .01) as well as a higher probability for CAL loss with an increasing vertical extent of a three‐walled defect component (linear: p = .008). Cox proportional hazard analysis showed a positive association between PlI after 12 months and tooth loss (p = .046).ConclusionRegenerative therapy of IBDs showed stable results over 9 years. CAL gain is associated with CAL after 12 months and decreasing initial defect depth in a three‐walled defect morphology. Tooth loss is associated with PlI 12 months post operation.Clinical trial number: DRKS00021148 (URL: https://drks.de).
Newly discovered knowledge pertaining to glucagon and its clinical applications
Authors: Kawamori Dan , Sasaki Shugo 
Published: April 2023

AbstractGlucagon has been defined as an ‘insulin counteracting hormone’, which raises blood glucose levels. Recent progress in basic research has shown that glucagon is closely involved in glucose and amino acid metabolism. Additionally, its secretion is intricately, but precisely, regulated by various mechanisms involving molecules in addition to glucose, thus showing its critical role in systemic nutrient metabolism. An innovative dual‐antibody‐linked immunosorbent assay for glucagon that improves measurement accuracy has been developed, and substantial clinical findings have been obtained using this new system. This discovery expanded the pathophysiological significance of glucagon and accelerated the development of its clinical applications in diabetes.
Factors influencing the downstream passage of European silver eels (Anguilla anguilla) through a tidal sluice
Authors: Huisman Jeroen B.J. , Höhne Leander , Hanel Reinhold , Kuipers Henry , Schollema Peter Paul , Nagelkerke Leopold 
Published: April 2023

AbstractTidal sluices are a frequent element in the tidal regions of Europe's rivers and may hinder downstream migrating European eels Anguilla anguilla. Sea level rise will reduce the possibility for tidal sluices to freely discharge water, further compressing windows of opportunity for the passage of eels. Understanding how eels utilize the discharge events of tidal sluices and which conditions facilitate successful passage is pivotal for the design of effective fish migration measures. To investigate eel migration at a tidal sluice, acoustic receivers were placed at the tidal sluice Nieuwe Statenzijl and in its tributary of the Westerwoldse Aa, the Netherlands. Of the 30 tagged eels, 26 eels reached the tidal sluice and passage success was 100%. The mean migration speed of eels in the unobstructed part of the tributary was slow (0.14 m s−1). The eels were delayed in their migration by the sluice and delay was right‐skewed distributed with most eels showing moderate delays (<2 days), while about 10% of the tagged individuals experienced extensive delays of more than 3 weeks. The number of missed sluicing events prior to successful passage was influenced by biological characteristics such as migration speed in the tributary, weight and condition. In addition, sluicing events with rapidly increasing and high maximum discharge levels increased the success rate of an individual eel to pass the sluice. Compromising sluicing duration in favour of higher and faster increasing discharge could facilitate eel migration at tidal barriers and contribute to the recovery of this endangered species.
Longitudinal associations of parental psychological control and friend support with autonomy during early adolescence
Authors: Wang Jingyun , Kaufman Tessa , Branje Susan 
Published: April 2023

AbstractAlthough theories suggest transactional associations between adolescents' autonomy and relationships with parents and friends, few studies have examined these within‐person effects. This longitudinal study examined the within‐person co‐development of adolescents' autonomy and relationships with parents and friends. Adolescents (N = 244 Mage = 11.54, SD = 0.43 at T1; 50% boys) participated in a four‐wave study across 2 years in the Netherlands. In random‐intercept cross‐lagged panel models, within‐person results showed that higher levels of autonomy predicted less parental psychological control but not vice versa. However, no lagged‐effects between friend support and autonomy were found. This study suggests that adolescents' autonomy steers changes in parental psychological control.
Re‐Imagining Reproduction: Citation and Chosen Kin
Authors: Mkhwanazi Nolwazi 
Published: April 2023

AbstractReproduction is political. Citation is political. In this essay, I link the anthropological concept of reproduction (biological and social), which is closely tied to kin‐making, to citation. I suggest that citation can be viewed as “academic” reproduction and kin‐making. To make this argument, I describe my professional and intellectual journey as a Black woman anthropologist based in the global South. I show how the amalgamation of the various contexts in which I was immersed brought up questions of race, nationality, colonialism, profession, and gender and influenced the direction my research took, as well as my scholarly position and engagement. In the article, I lay bare the academic stakes of the path that I have chosen. [citation, reproduction, scholarship, politics, anthropology]
Thermal preference of adult mosquitoes (Culicidae) and biting midges (Ceratopogonidae) at different altitudes in Switzerland
Authors: Hug David O. H. , Stegmayer Raffael I. , Blanckenhorn Wolf U. , Verhulst Niels O. 
Published: April 2023

AbstractMosquitoes (Diptera: Culicidae) and biting midges (Diptera: Ceratopogonidae) are among the most important vectors of human and veterinary pathogens. For modelling the distribution of these pathogens, entomological aspects are essential, which in turn are highly dependent on environmental factors, such as temperature. In this study, mosquitoes and biting midges were sampled in multiple microclimates at two low (360, 480 meters above sea level, m.a.s.l.) and two high (1250, 1530 m.a.s.l.) altitude locations in Switzerland. Sets of various traps (CO2‐baited CDC, LED‐UV, resting boxes, oviposition cups) equipped with dataloggers were placed in transects at five sites with similar vegetation at each location. Only the CDC and the LED‐UV traps collected enough insects for analyses. Taxonomic diversity was greater for mosquitoes but lower for biting midges at lower altitudes. Both mosquitoes and biting midges had a thermal preference. Culicoides preferred the traps with warmer microclimate, especially at lower altitudes, whereas mosquito preferences depended on the species, but not on altitude. Relative humidity had a significant positive impact on catches of biting midges but not mosquitoes. To obtain better data on thermal preferences of resting and ovipositing vectors in addition to host seeking individuals, new and improved collecting methods are needed.
A contemporary investigation of burden and natural history of aspergillosis in people living with HIV/AIDS
Authors: Truda Vanessa Souza Santos , Falci Diego Rodrigues , Porfírio Fátima Maria Venancio , de Santos Daniel Wagner de Castro Lima , Junior Francisco Ivanildo Oliveira , Pasqualotto Alessandro Comaru , Puga Fernanda Guioti , Bollela Valdes Roberto , Junior João Nobrega Almeida , Ferreira Paulo Roberto Abrão , Colombo Arnaldo Lopes 
Published: April 2023

AbstractBackgroundUntreated HIV infection can lead to profound immunosuppression and increase susceptibility of people living with HIV/AIDS (PLHA) to aspergillosis.ObjectivesReporting the burden and natural history of aspergillosis documented in PLHA admitted in five medical centres in Brazil.Patients and MethodsClinical, epidemiological and laboratory data were collected in all sequential cases of proven or probable aspergillosis documented in PLHA hospitalised in five medical centres between 2012 and 2020.ResultsWe enrolled 25 patients ageing between 23 and 58 years (mean = 39) including 11 patients with invasive aspergillosis (IA) and 14 with chronic pulmonary aspergillosis (CPA). The prevalence rate of aspergillosis was 0.1% of 19.616 PLHA. Overall, 72.7% of patients with IA exhibited CD4 < 100 cells/mL and 42.8% of patients with CPA exhibited CD4 count >200 cells/mL. Most patients had a history of tuberculosis, especially those with CPA (85.7%). IA was documented after a mean of 16.5 days of hospitalisation, mainly in critically ill patients exposed to corticosteroids and broad‐spectrum antibiotics. In the CPA group, a positive culture (71.4%) and radiological alterations were the most frequent findings supporting their diagnosis. Episodes of IA were mostly documented by tissue biopsies. Crude mortality rates were 72.7% and 42.8% in patients with IA and CPA, respectively.ConclusionsDespite being considered an unusual complication in PLHA (0.1%), IA should be considered in patients with profound immunosuppression and pneumonia refractory to conventional therapy. CPA should be investigated in PLHA with chronic deterioration of pulmonary function and previous diagnosis of tuberculosis.
Online pain management programs for chronic, widespread musculoskeletal conditions: A systematic review with meta‐analysis
Authors: Chew Min Tze , Chan Cliffton , Kobayashi Sarah , Cheng Hoi Yan , Wong Tsz Ming , Nicholson Leslie L. 
Published: April 2023

AbstractFace‐to‐face pain management programs demonstrate positive clinical outcomes in the chronic pain population by improving pain intensity and attitudes, depression, and functional disability scores. The effects of this modality carried out online is less known, particularly in subgroups of chronic pain. This systematic review assessed the effects of online pain management programs in chronic, widespread musculoskeletal conditions on pain measurements (intensity, interference, coping, and catastrophizing), health‐related quality of life, depression, and anxiety scores immediately post‐intervention. Five electronic databases (Embase, Medline, CINAHL, Scopus, and PEDro) were searched with 3546 studies identified. Eighteen randomized controlled trials fulfilled the inclusion criteria. Included studies had moderate methodological quality (using the Effective Public Health Practice Project (EPHPP) quality assessment tool) but high risk of bias (using the revised Cochrane risk‐of‐bias tool for randomized trials (RoB 2)). There were significant improvements in pain intensity (11 studies, 1397 participants, SMD −0.30, 95% CI −0.50 to −0.10, p = 0.004), health‐related quality of life (eight studies, 1054 participants, SMD 0.41, 95% CI 0.08 to 0.75, p = 0.02), and depression (nine studies, 1283 participants, SMD −0.32, 95% CI −0.55 to −0.08, p = 0.008). However, effect sizes were small and did not meet their respective measure's minimal clinically important change score. Guided interventions (regular interaction with an instructor) appeared to be superior to self‐completed interventions. Future research should standardize outcome measures for assessing pain, use active control groups, and analyze other outcome measures such as cost and long‐term effects. This study was registered with Prospero on August 15, 2021 (CRD42021267565).
Azelaic and hexanoic acids‐inducing resistance in soybean against Phakopsora pachyrhizi infection
Authors: Rodrigues Flávia Caroline Torres , Silveira Patricia Ricardino , Cacique Isaias Severino , Oliveira Lillian Matias , Rodrigues Fabrício A. 
Published: April 2023

AbstractRust in soybean, caused by Phakopsora pachyrhizi, has been controlled using different fungicide molecules. This study pinpoints the use of inducers of resistance as a promising alternative by investigating the hypothesis that reduction in rust symptoms on soybean sprayed with azelaic acid (AzA) and hexanoic acid (HxA) is linked to a fungistatic effect against urediniospore germination of P. pachyrhizi and/or through the potentiation of host defence reactions. A 4 × 2 factorial experiment was designed consisting of plants sprayed with water (control), acibenzolar‐S‐methyl (ASM), AzA or HxA and either non‐inoculated or inoculated with P. pachyrhizi. Both AzA and HxA significantly inhibited urediniospore germination in vitro. The area under disease progress curve significantly decreased for ASM, HxA (5 and 20 mM) and AzA (0.1 and 1 mM), and fewer hyphae of P. pachyrhizi colonized tissues of plants sprayed with ASM, HxA (20 mM) and AzA (1 mM), compared to control. Host defence genes were strongly up‐regulated for infected plants sprayed with AzA, ASM and HxA compared to water. Most of these genes were expressed earlier for infected and HxA‐sprayed plants than for infected and AzA‐sprayed plants and at greater expression levels than infected and ASM‐sprayed plants. The physiological, biochemical and molecular responses obtained with AzA‐ and HxA‐sprayed plants were comparable to ASM, a well‐known inducer of resistance. This study highlights the potential of using AzA and HxA for rust management considering their fungistatic effect against urediniospores and the capacity to provide soybean plants with a more efficient defence against P. pachyrhizi infection.
Parents' experiences of their child's participation in divorce groups in Norway: A phenomenological study
Authors: Ulvøy Dagny‐Elise , Åvik Persson Helene , Kristensson Hallström Inger , Sollesnes Ragnhild 
Published: April 2023

AbstractBackgroundChildren and youth who experience divorce are found to have increased risk of emotional and behavioural adjustment problems. Different prevention programmes have been developed to help and support children. Previous studies have focused on the child or the group leader's experience with divorce groups, but studies describing parent's experience are missing. The aim of this study was to explore parents' experiences of their child's participation in divorce groups.MethodsAn inductive, qualitative and descriptive design was applied with philosophical orientation in naturalistic inquiry based on the outlines of a phenomenological perspective. Two fathers and three mothers from two different counties in Norway participated whereof four of them were interviewed twice. Systematic text condensation was used for the analysis.ResultsThree themes emerged from the analysis: encouraging the child, missing communication and challenging situations. Parents described how they encouraged the child to attend divorce groups and hoped they would gain a deeper understanding of their parents' divorce and their own feelings. Missing communication relates to lack of information about the groups from the school, the group leader and from the child. Missing information was found to be a challenge for the parents and made them think that the divorce group was beneficial for the child but maybe not always for the family. Parents described challenging situations due to the divorce, and they struggled to understand their child and their own behaviour.ConclusionsThe opportunity for the child to talk to other children in the same situation in divorce groups was positive for the parents. To be beneficial for both children and their parents, structured information and cooperation among the school, the child and both parents are important. The knowledge from this study can support the development and use of intervention programmes in the future.
Educational approaches to teach students to address colonialism in global health: a scoping review
Authors: Perkins Sylvie , Nishimura Holly , Olatunde Praise F , Kalbarczyk Anna 
Published: April 2023

IntroductionThe enduring legacy of colonisation on global health education, research and practice is receiving increased attention and has led to calls for the ‘decolonisation of global health’. There is little evidence on effective educational approaches to teach students to critically examine and dismantle structures that perpetuate colonial legacies and neocolonialist control that influence in global health.MethodsWe conducted a scoping review of the published literature to provide a synthesis of guidelines for, and evaluations of educational approaches focused on anticolonial education in global health. We searched five databases using terms generated to capture three concepts, ‘global health’, ‘education’ and ‘colonialism’. Pairs of study team members conducted each step of the review, following Preferred Reporting Items for Systematic reviews and Meta-Analyse guidelines; any conflicts were resolved by a third reviewer.ResultsThis search retrieved 1153 unique references; 28 articles were included in the final analysis. The articles centred North American students; their training, their evaluations of educational experiences, their individual awareness and their experiential learning. Few references discussed pedagogical approaches or education theory in guidelines and descriptions of educational approaches. There was limited emphasis on alternative ways of knowing, prioritisation of partners’ experiences, and affecting systemic change.ConclusionExplicit incorporation of anticolonial curricula in global health education, informed by antioppressive pedagogy and meaningful collaboration with Indigenous and low-income and middle-income country partners, is needed in both classroom and global health learning experiences.
Physical performance testing in post-COVID-19 patients: protocol for a systematic review of psychometric measurement properties
Authors: Nascimento Larissa Fernanda Estevam do , Mendes Luciana Andrade , Torres-Castro Rodrigo , Fregonezi Guilherme AF , Gimeno-Santos Elena , Vilaró J , Resqueti Vanessa R 
Published: April 2023

IntroductionCOVID-19 is an infectious disease that causes severe acute respiratory syndrome. A large variety of exercise capacity tests are used for the evaluation of post-COVID-19 patients, but the psychometric properties of these exercise tests remain undetermined in this population. This study aims to critically appraise, compare and summarise the psychometric properties (validity, reliability and responsiveness) of all physical performance tests that are used to assess exercise capacity in post-COVID-19 patients.Methods and analysisThis systematic review protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. We will include studies with hospitalised adult post-COVID-19 patients (aged 18 years or older and with a confirmed diagnosis of COVID-19). The research will cover randomised controlled trials (RCTs), quasi-RCTs and observational studies published in English and performed in the following settings: hospital, rehabilitation centre, outpatient clinic. We will search the following databases with no date restrictions: PubMed/MEDLINE, EMBASE, SciELO, Cochrane Library, CINAHL and Web of Science. Two authors will independently assess the risk of bias (using the Consensus-Based Standards for the Selection of Health Measurement Instruments Risk of bias checklist) and the certainty of evidence (using the Grading of Recommendations, Assessment, Development and Evaluations). According to the results obtained, data will be meta-analysed or reported narratively.Ethics and disseminationNo ethical approval is required for this publication since it will be based on published data. Results of this review will be disseminated via peer-reviewed publications and conference presentations.PROSPERO registration numberCRD42021242334.
Delays in seeking, reaching and access to quality cancer care in sub-Saharan Africa: a systematic review
Authors: Lombe Dorothy Chilambe , Mwamba Monde , Msadabwe Susan , Bond Virginia , Simwinga Musonda , Ssemata Andrew Sentoogo , Muhumuza Richard , Seeley Janet , Mwaka Amos Deogratius , Aggarwal Ajay 
Published: April 2023

ObjectivesLate presentation and delays in diagnosis and treatment consistently translate into poor outcomes in sub-Saharan Africa (SSA). The aim of this study was to collate and appraise the factors influencing diagnostic and treatment delays of adult solid tumours in SSA.DesignSystematic review with assessment of bias using Risk of Bias in Non-randomised Studies of Exposures (ROBINS-E) tool.Data sourcesPubMed and Embase, for publications from January 1995 to March 2021.Eligibility criteriaInclusion criteria: quantitative or mixed-method research, publications in English, on solid cancers in SSA countries. Exclusion criteria: paediatric populations, haematologic malignancies, and assessments of public perceptions and awareness of cancer (since the focus was on patients with a cancer diagnosis and treatment pathways).Data extraction and synthesisTwo reviewers extracted and validated the studies. Data included year of publication; country; demographic characteristics; country-level setting; disease subsite; study design; type of delay, reasons for delay and primary outcomes.Results57 out of 193 full-text reviews were included. 40% were from Nigeria or Ethiopia. 70% focused on breast or cervical cancer. 43 studies had a high risk of bias at preliminary stages of quality assessment. 14 studies met the criteria for full assessment and all totaled to either high or very high risk of bias across seven domains. Reasons for delays included high costs of diagnostic and treatment services; lack of coordination between primary, secondary and tertiary healthcare sectors; inadequate staffing; and continued reliance on traditional healers and complimentary medicines.ConclusionsRobust research to inform policy on the barriers to quality cancer care in SSA is absent. The focus of most research is on breast and cervical cancers. Research outputs are from few countries. It is imperative that we investigate the complex interaction of these factors to build resilient and effective cancer control programmes.