bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metagenomics revealed a correlation of gut phageome with autism spectrum disorder
Authors: Shahin Khashayar , Soleimani-Delfan Abbas , He Zihan , Sansonetti Philippe , Collard Jean-Marc 
Published: August 2023

AbstractThe human gut bacteriome is believed to have pivotal influences on human health and disease while the particular roles associated with the gut phageome have not been fully characterized yet with few exceptions. It is argued that gut microbiota can have a potential role in autism spectrum disorders (ASD). The public microbiota database of ASD and typically developing (TD) Chinese individuals were analyzed for phage protein-coding units (pPCU) to find any link between the phageome and ASD. The gut phageome of ASD individuals showed a wider diversity and higher abundance compared to TD individuals. The ASD phageome was associated with a significant expansion of Caudoviricetes bacteriophages. Phages infecting Bacteroidaceae and prophages encoded within Faecalibacterium were more frequent in ASD than in TD individuals. The expansion and diversification of ASD phageome can influence the bacterial homeostasis by imposing pressure on the bacterial communities. In conclusion, the differences of phages community in in ASD and TD can be used as potential diagnosis biomarkers of ASD. Further investigations are needed to verify the role of gut phage communities in the pathogenesis of ASD.
Monitoring montane-subalpine forest ecotone in the Pyrenees through sequential forest inventories and Landsat imagery
Authors: Aulló-Maestro Isabel , Gómez Cristina , Hernández Laura , Camarero J. Julio , Sánchez-González Mariola , Cañellas Isabel , Vázquez de la Cueva Antonio , Montes Fernando 
Published: August 2023

AbstractKey messageAbies albaMill.–Pinus uncinataRamond. ecotone dynamics are examined along both altitudinal and protection level gradients by combining field inventories and Landsat data. An upward expansion ofA. albato the subalpine belt is observed in the last decades as a result of stand maturation after logging cessation.ContextHigh-mountain forests constitute sensitive locations to monitor the impacts of global change on tree-species composition and ecotone dynamics. In this study, we focus on the Spanish Pyrenees where silver fir (Abies albaMill.) coexists with mountain pine (Pinus uncinataRamond.) forming montane-subalpine ecotones.AimsThe main goal of this study is to assess the spatiotemporal dynamics of the silver fir–mountain pine ecotone and its underlying driving factors.MethodsWe reconstructed the spatial distribution and dynamics of the species by combining remote sensing imagery and field plot data from 1989 to 2015, employing support vector machine techniques for image classification. Using variance analysis and mixed effects models, we then analyzed the evolution of basal area and replacement index, a measure of relative change in species composition, over time and altitude range. Additionally, we explored their relationship with site factors and protection level (National Park vs. protection buffer zone).ResultsSilver fir has expanded its distribution in both the National Park and the protection buffer zone, whereas mountain pine has remained stable. Both species exhibit increased basal area associated with stand maturation and a higher level of protection. The replacement index indicates a rise in silver fir in the understory on North-facing slopes, attributed to stand densification. These findings are particularly noticeable in the area with the highest level of protection.ConclusionThe cessation of traditional land uses has led to ongoing stand densification, promoting succession and favoring the increased abundance of silver fir at its uppermost locations, where this species outcompetes mountain pine.
Driving mechanisms of productivity stability vary with selective harvesting intensities in a mixed broad-leaved Korean pine forest
Authors: Geng Yan , Xiang Kehan , Zhang Chunyu , Zhao Xiuhai 
Published: August 2023

Abstract
Key message
We found that the stabilizing mechanisms for forest productivity varied across harvesting intensities in a mixed broad-leaved Korean pine forest. Effects of overyielding at high species richness and species asynchrony occurred only in unharvested and lightly harvested plots, whereas asymmetries between individuals of different size contributed significantly to stabilizing productivity when harvestings became intensive.

Context
Understanding the driving factors of forest ecosystem stability has become increasingly crucial in forest management. However, it remains unclear whether and how the stabilizing mechanisms of forest productivity might be influenced by management practices.

Aims
We related the temporal stability of aboveground biomass productivity to harvesting history. We further tested how three key driving mechanisms of stability might be modulated by selective harvesting intensities.

Methods
Based on a 10-year monitoring (five repeated tree inventories) of a mixed broad-leaved Korean pine forest in Northeastern China recovering from selective harvesting, we examined the relative importance of two diversity-dependent mechanisms (overyielding and species asynchrony) and one size-dependent mechanism (asymmetric growth) for productivity stability across a wide range of intensities (0–73.4% basal area removed).

Results
We found that selective harvesting significantly lowered the productivity stability, species asynchrony, and growth dominance coefficient. Growth dominance coefficient had an overall stronger effect on stability than species richness and asynchrony. Moreover, the strengths of stabilizing mechanisms varied across harvesting intensities: effects of overyielding at high species richness and species asynchrony were detected only in unharvested and lightly harvested plots, whereas the explanatory power of growth dominance coefficient outweighed the diversity-related variables when harvesting became intensive.

Conclusions
We emphasized the importance to consider both diversity- and size-related explanatory variables as potential mechanisms for the temporal stability of forest productivity. In fact, how growth is partitioned among trees of different species as well as sizes may co-determine the response of forest stability to disturbances.
How to improve the accuracy of height data from bird tracking devices? An assessment of high-frequency GPS tracking and barometric altimetry in field conditions
Authors: Schaub Tonio , Millon Alexandre , De Zutter Caroline , Buij Ralph , Chadœuf Joël , Lee Simon , Mionnet Aymeric , Klaassen Raymond Hendrikus Gerardus 
Published: August 2023

Abstract
Background
In the context of rapid development of wind energy infrastructure, information on the flight height of birds is vital to assess their collision risk with wind turbines. GPS tags potentially represent a powerful tool to collect flight height data, yet GPS positions are associated with substantial vertical error. Here, we assessed to what extent high-frequency GPS tracking with fix intervals of 2–3 s (GPS remaining turned on between fixes), or barometric altimetry using air pressure loggers integrated in GPS tags, improved the accuracy of height data compared to standard low-frequency GPS tracking (fix interval ≥ 5 min; GPS turned off between fixes).

Results
Using data from 10 GPS tag models from three manufacturers in a field setting (194 tags deployed on free-living raptors), we estimated vertical accuracy based on periods when the birds were stationary on the ground (true height above ground was approximately zero), and the difference between GPS and barometric height in flight. In GPS height data, vertical accuracy was mainly driven by noise (little bias), while in barometric data, it was mostly affected by bias (little noise). In high-frequency GPS data, vertical accuracy was improved compared to low-frequency data in each tag model (mean absolute error (AE) reduced by 72% on average; range of mean AE 2–7 vs. 7–30 m). In barometric data, vertical accuracy did not differ between high- and low-frequency modes, with a bias of − 15 to − 5 m and mean AE of 7–15 m in stationary positions. However, the median difference between GPS and barometric data was smaller in flight positions than in stationary positions, suggesting that the bias in barometric height data was smaller in flight. Finally, simulations showed that the remaining vertical error in barometric and high-frequency GPS data had little effect on flight height distributions and the proportion of positions within the collision risk height range, as opposed to the extensive noise found in low-frequency GPS data in some tag models.

Conclusions
Barometric altimetry may provide more accurate height data than standard low-frequency GPS tracking, but it involves the risk of a systematic error. Currently, high-frequency GPS tracking provides highest vertical accuracy and may thus substantially advance the study of wind turbine collision risk in birds.
Early intervention to prevent adverse child emotional and behavioural development following maternal depression in pregnancy: study protocol for a randomised controlled trial
Authors: Milgrom Jeannette , Hirshler Yafit , Holt Charlene , Skouteris Helen , Galbally Megan , East Christine , Glover Vivette , Reece John , O’Donnell Kieran J. , Walker Susan P. , Malloy Shannon , Gemmill Alan W. 
Published: August 2023

Abstract
Background
Substantial evidence indicates that maternal depression during pregnancy (i.e., antenatal depression) is associated not only with maternal wellbeing but also with child emotional and behavioural development. Children of antenatally depressed women are at risk of emotional and behavioural problems, including internalising problems (e.g., anxiety and depression) and externalising problems (e.g., attention problems), that may last at least to adolescence. These enduring effects also constitute an enormous economic cost. Despite the seriousness of this problem, until recently there existed very few controlled studies evaluating whether active psychological treatment for antenatal depression can prevent adverse child outcomes. Our previous pilot randomised controlled trial (RCT) exploring the effect of cognitive behavioural therapy (CBT) for antenatal depression on child outcomes showed promising results. We aim to assess whether treating antenatal depression with an evidence-based 8-week structured CBT program can prevent or ameliorate adverse child developmental outcomes at 2 years of age.

Methods
Pregnant women ≤ 30 weeks gestation diagnosed with a depressive disorder are recruited and randomised to CBT or treatment as usual (TAU). The target sample size is 230 and the primary outcome measure is the infant Internalising scale of the Child Behaviour Checklist (CBCL) at 24 months of age. Secondary infant outcome measures at 24 months are the Externalising scale of the CBCL and the motor and cognitive development subscales of the Ages & Stages Questionnaire (ASQ-3). Additional secondary outcome measures are subscales of the Revised Infant Behaviour Questionnaire (IBQ-R), ASQ-3 and the ASQ-Socio-Emotional (ASQ-SE) at 3 and 12 months of age and the quality of mother-infant interaction at 3 and 24 months. Maternal measures, including demographic data, depression diagnosis, depressive and anxiety symptoms, perceived stress and parenting stress, are collected across all time points.

Discussion
The trial is ongoing and recruitment was slowed due to the COVID-19 pandemic. If results suggest a beneficial effect of antenatal depression treatment on infant outcomes, the project could have repercussions for standard antenatal care, for maternal and infant health services and for preventing the intergenerational transmission of mental health disorders.

Trial registration
Australia and New Zealand Clinical Trials Register: ACTRN12618001925235 Date Registered: 27 November 2018.
The role of telemedicine in joint replacement surgery? An updated review
Authors: Li Ka Yau , Chan Ping Keung , Yeung Shun Shing , Cheung Amy , Chan Wai Kwan Vincent , Luk Michelle Hilda , Cheung Man Hong , Fu Henry , Chiu Kwong Yuen 
Published: August 2023

AbstractThe usage of telemedicine and telehealth services has grown tremendously and has become increasingly relevant and essential. Technological advancements in current telehealth services have supported its use as a viable alternative tool to conduct visits for consultations, follow-up, and rehabilitation in total joint arthroplasty. Such technology has been widely implemented, particularly during the coronavirus 2019 (COVID-19) pandemic, to deliver postoperative rehabilitation among patients receiving total joint arthroplasty (TJA), further demonstrating its feasibility with a lower cost yet comparable clinical outcomes when compared with traditional care. There remains ample potential to utilize telemedicine for prehabilitation to optimize the preoperative status and postoperative outcomes of patients with osteoarthritis. In this review, various implementations of telemedicine within total joint arthroplasty and future application of telemedicine to deliver tele-prehabilitation in TJA are discussed.
Impact of Breast Cancer Screening on 10-Year Net Survival in Canadian Women Age 40-49 Years
Authors: Wilkinson Anna N. , Ellison Larry F. , Billette Jean-Michel , Seely Jean M. 
Published: August 2023

PURPOSE In Canada, some provincial/territorial mammography screening programs include women age 40-49 years, whereas others do not. This study examines the impact of this dichotomy on the 10-year breast cancer (BC) net survival (NS) among women age 40-49 years and 50-59 years at diagnosis. METHODS Using the Canadian Cancer Registry data record linked to death information, we evaluated the cohort of Canadian women age 40-49 years and 50-59 years diagnosed with BC from 2002 to 2007. We compared 10-year NS estimates in the jurisdictions with organized screening programs that included women age 40-49 years, designated as screeners (Northwest Territories, British Columbia, Alberta, Nova Scotia, and Prince Edward Island), with comparator programs that did not (Yukon, Manitoba, Saskatchewan, Ontario, Quebec, New Brunswick, and Newfoundland and Labrador). RESULTS BC was the primary cause of 10-year mortality in women age 40-49 years diagnosed with BC (90.7% of deaths). Among these women, the 10-year NS for screeners (84.8%; 95% CI, 83.8 to 85.8) was 1.9 percentage points (pp) higher than that for comparators (82.9%; 95% CI, 82.3 to 83.5; P = .001). The difference in favor of screeners was significant among women age 45-49 years (2.6 pp; P = .001) but not among women age 40-44 years (0.9 pp; P = .328). Similarly, the incidence-based BC mortality rate was significantly lower in screener jurisdictions among women age 40-49 years and 45-49 years, but not for 40-44 years. Provincial/territorial NS increased significantly with higher mammography screening participation ( P = .003). The BC incidence rate was virtually identical in screener and comparator jurisdictions among women age 40-49 years ( P = .976) but was significantly higher for comparators among women age 50-59 years ( P < .001). CONCLUSION Screening programs that included women in their 40s were associated with a significantly higher BC 10-year NS in women age 40-49 years, but not an increased rate of BC diagnosis. These results may inform screening guidelines for women age 40-49 years.
Optimizing Lung Cancer Screening With Risk Prediction: Current Challenges and the Emerging Role of Biomarkers
Authors: Wu Julie Tsu-yu , Wakelee Heather A. , Han Summer S. 
Published: August 2023

The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice. Lung cancer screening has been demonstrated to reduce lung cancer mortality, but its benefits must be weighed against the potential harms of unnecessary procedures, false-positive radiological findings, and overdiagnosis. Individuals at highest risk of lung cancer are more likely to maximize benefits while minimizing harm from screening. Although current lung cancer screening guidelines recommended by the US Preventive Services Task Force (USPSTF) only consider age and smoking history for screening eligibility, National Comprehensive Cancer Network and other society guidelines recommend screening on the basis of individualized risk assessment including family history, environmental exposures, and presence of chronic lung disease. Risk prediction models have been developed to integrate various risk factors into an individualized risk prediction score. Previous evidence showed that risk prediction model-based screening eligibility could improve sensitivity for detecting lung cancer cases without reducing specificity. Furthermore, recent advances in lung cancer biomarkers have enhanced the performance of risk prediction in identifying lung cancer cases relative to the USPSTF criteria. These risk prediction models can be used to guide shared decision-making discussions before proceeding with lung cancer screening. This study aims to provide a concise overview of these prediction models and the emerging role of biomarker testing in risk prediction to facilitate conversations with patients. The goal was to assist clinicians in assessing individual patient risk, leading to more informed decision making.
Impact of Childhood Cancer on Growth
Authors: Yoshida Tomoko , Delaney Angela 
Published: August 2023

Abstract
Along with improvements in cancer treatment over time, the number of childhood cancer survivors has been growing. Survivors are at risk for serious medical complications, and growth impairment is among the most common. There are multiple factors that may cause impaired growth among survivors. In this article, we review the impact of cancer on growth in children and adolescents. We first provide an overview of growth disturbance among childhood cancer patients and survivors due to nonhormonal causes, including a recent understanding of the effect of targeted cancer therapies (eg, tyrosine kinase inhibitors and immune checkpoint inhibitors) on growth. Then we describe the hormonal causes of growth impairment among survivors, focusing on growth hormone deficiency, including the prevalence, risk factors, and treatment. Lastly, we briefly summarize overgrowth and tall stature in childhood cancer. It is critical to assess the linear growth of children and adolescents, especially in cancer survivors who are at risk for growth disturbance, since growth is an important measure of their health.
Color Tunable Circularly Polarized Luminescence Properties of Chiral Platinum(II) Complexes with Salen Ligands
Authors: Ikeshita Masahiro , Tani Yuki , Kitahara Maho , Imai Yoshitane , Tsuno Takashi 
Published: August 2023

Abstract
A series of novel chiral platinum complexes 1–8 (R = 4-NEt2 (1), 4-F (2), 5-CF3 (3), 5-Cl (4), 5-OCF3 (5), 4-CF3 (6), 5-F (7), 5-MeO (8)) was prepared and their circularly polarized luminescence (CPL) properties were compared with those of the non-substituted analogue 9 (R = H). The complexes showed multi-color (green, yellow, and red) phosphorescence in the solution state, depending on the substitution position of the functional group of the ligands. The chiral complexes exhibited CPL with absolute luminescence dissymmetry factor (glum) of up to the 1.3 × 10−3 in the dilute solution state. Acid-induced CPL was also achieved by the protonation of the diethylamino group of complex 1 with CH3SO3H. Density functional theory (DFT) calculations were conducted to further understand the structure dependence of the chromogenic behavior of these complexes.
ΜΑΡΙΑ ΧΑΤΖΗΚΥΡΙΑΚΙΔΟΥ, Η Ιταλία του Νίκου Εγγονόπουλου
Authors: Χατζηκυριακίδου Μαρία 
Published: August 2023

The Italy of Nikos Eggonopoulos
The presence of the Italian culture is reflected in all kinds of art with which the diverse representative of Greek surrealism Nikos Eggonopoulos dealt. «Although, […], the French fed my childhood dreams with Italy and Spain, I [only] loved Italy, and then got to know it in person» he wrote to his later wife, underlining the theoretical and experiential stimuli he received from the other side of the Adriatic coast. From the brush to the pen and vice versa, through reflections and patterns, the Italian landscape, the visual arts, the historical and literary reality and, of course, the monuments of Italy «rest his soul» and exert, as he states, a «deep and invincible» charm for him.
But beyond the observations and critical thoughts about Italy as a historical and cultural entity, the Italian culture is part of the artistic ecosystem created by Eggonopoulos. He combines, seemingly incongruously, the painters and poets of Italy by placing them next to ordinary people or Greek deities while, conversely, Greek poets are depicted in his paintings with Venetian masks and renaissance attire or are described in his poems wandering in the streets of Venice. In this way he achieves multiple connections between the arts and the spaces, creating mixed forms and approaches that seem to have a common denominator: the answer to the question that concerns the origins of the Greek identity. Although in his time such a thing was treated as heretical, for Eggonopoulos these effects not only do not alter but, on the contrary, renew the cultural creation, enhancing the uniqueness, the dynamics and the universality of Greek culture.
ΜΙΧΑΛΗΣ ΧΡΥΣΑΝΘΟΠΟΥΛΟΣ, Υπερρεαλιστικά εγκώμια υπερρεαλιστών: Ανταγωνισμός μεταξύ Διοσκούρων;
Authors: Χρυσανθόπουλος Μιχάλης 
Published: August 2023

Surrealist “praises” (encomia) of surrealists: Empeirikos and Engonopoulos compete?
The purpose of the paper is to explore the way the Greek surrealists, Andreas Empeirikos and Nikos Engonopoulos, use the form of the “praise” (encomium) in a fashion that relates to the Ancient Greek tradition and to its Renaissance revival (e.g. Erasmus, “Praise of Folly”), in order to establish the basic principles of their approaches, to deal with negative criticism of their work, to underscore the merits of the ideas and the work of their seniors, but, also, to playfully criticise them and, last but not least, to support and praise each other. The period examined in detail is that from 1935 to 1945, while emphasis is laid on Empeirikos’ long “praise” of Engonopoulos published in 1945, which redrew the rules. The surrealist “praise” is examined as a “agonistic” form, as a competition between poets and artists and as a defensive weapon against malevolent attacks from critics.