bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economía de sitios o estancias de labor y vegas de tabaco en la jurisdicción de Holguín, 1752- 1868
Authors: Abreu-Pupo Alexander , Córdova-Martínez Carlos Antonio , Guerra-Gómez David 
Published: December 2022

En el presente artículo, los autores reconstruyeron el escenario agrario de los sitios o estancias de labor y las vegas de tabaco de Holguín, una Región Histórica cuya jurisdicción fue de fundación tardía. La información obtenida y procesada requirió del trabajo con documentos de archivo. El método esencial fue el hermenéutico, asumido desde la dialéctica de los procesos socioeconómicos, el análisis estructural y el movimiento de larga duración con sus fluctuaciones cíclicas. La investigación demuestra que este tipo de economía dominó el panorama regional. Finalmente, se comprueba que en la región el sector de pequeños agricultores de cultivos varios y tabaco, se encontraba en 1868 en una situación de crisis por hipotecas, bajas capacidades financieras y tecnológicas, e imposibilitado para revitalizar de este tipo de agricultura; en un contexto que apuntaba a los procesos de concentración y centralización de la propiedad y los capitales activados hacia formas mercantiles de producción capitalistas.
Palabras clave:
Región Histórica de Holguín, agricultura, sitios o estancias de labor, vegas de tabaco.

ABSTRACT
In this article, the authors reconstruct the agrarian scenario of the work sites or ranches and the tobacco plantations in Holguín, historical region whose jurisdiction was of late foundation. The information obtained and processed required work with archival documents. Hermeneutic was the essential method, assumed from the dialectic of the socioeconomics processes, structural analysis and long-term movement with its cyclical fluctuations. This research shoes that this type of economy dominated in the region. Finally, it is verified that the sector of small farmers of various crops and tobaccoin the region, were in 1868 in a situation of mortgage crisis, low financial and technological capacities, and unable to revitalize this type of agriculture; in a context that pointed to the processes of concentration of property and capital activated towards mercantile forms of capitalist production.
Keywords:
Historical Region of Holguín, agriculture, work sites or ranches, tobacco plantations.
Número completo (Enero-abril)
Authors: León-González PhD. Jorge Luis 
Published: December 2022

Editorial
PhD. Rolando Medina-Peña

Hipoplasia do esmalte em dentesdecíduos e permanentes. Policlínico Aracelio Rodríguez Castellón, município de Cumanayagua
Ana Belkys Hernández-Millán, Ailet Martínez-Bordón, Mayra García-Pernas, Diosky Ferrer-Vilches

Potencial de la vegetación en fincas de Santiago de Cuba para el control de plagas
Belyani Vargas-Batis, Yordi Mauro Ramos-García, Dayamí Guerrero-Hernández, Rubert Rodríguez-Fonseca, Giselle Bestard-Leyva, Adriel Plana-Quiala

Cuestionario para medir satisfacción de usuarios en los servicios de Estomatología General Integral
Claudia Leticia Cuéllar-González, José Luis Capote-Femenías

Implementación de un procedimiento de mejora de proceso en empresa comercializadora de cemento
Henrry Ricardo-Cabrera, Kenny Freire-Quevedo, Elizabeth Leal-Sarduy, Yesenia Abreus-Pérez

Economía de sitios o estancias de labor y vegas de tabaco en la jurisdicción de Holguín, 1752- 1868
Alexander Abreu-Pupo, Carlos Antonio Córdova-Martínez, David Guerra-Gómez

Análisis de la segmentación demográfica en un mercado agropecuario estatal de Santiago de Cuba
Miriela Rizo-Mustelier, Daniel Rafael Vuelta-Lorenzo

Aprendizaje por descubrimiento Vs aprendizaje tradicional
Eudaldo Enrique Espinoza-Freire
Efectos picosociales del Covid-19: desafíos para la equidad social
Authors: Calcerrada-Gutiérrez Marybexy , Pita-Simón Vladimir , Oliver-Castillo Gabriel Eduardo 
Published: December 2022

El artículo integra una reflexión respecto a los efectos psicosociales del Covid-19 en Cuba enlazados con perspectivas de solución dirigidas a dimensiones de la equidad social. En correspondencia con su objetivo, dedicado a estimular un análisis de las consecuencias sociales del Covid-19 en relación con dimensiones de equidad. Metodológicamente se fundamenta en la integración de resultados publicados respecto a efectos principalmente psicológicos de la enfermedad tanto a nivel internacional como nacional y la experiencia de evaluación psicosocial desplegada por los autores durante un año de evolución de este problema de salud en Cuba. Como principal contribución ofrece un análisis de las oportunidades y desafíos ante las consecuencias sociales de la crisis sanitaria para el desarrollo humano.
Palabras clave:
Covid-19, crisis sanitaria, equidad social.

ABSTRACT
The article includes a reflection on the psychosocial effects of Covid-19 in Cuba linked to solution perspectives directed at dimensions of social equity. In line with its objective, dedicated to stimulating an analysis of the social consequences of Covid-19 in relation to equity dimensions. Methodologically, it is based on the integration of published results regarding mainly psychological effects of the disease at both international and national levels and the psychosocial evaluation experience deployed by the authors during a year of evolution of this health problem in Cuba. As its main contribution, it offers an analysis of the opportunities and challenges in the face of the social consequences of the health crisis for human development.
Keywords:
Covid-19, health crisis, social equity.
Análisis de impacto regulatorio y autonomía municipal en Cuba
Authors: García-González Tania , Ochoa-del Río José Augusto 
Published: December 2022

En un mundo globalizado y complejo, como el de hoy, se hace necesario que el Derecho conozca y utilice una herramienta vital para la construcción de sus normas: el análisis de impacto regulatorio, que deviene como instrumento de la prospectiva jurídica. Se definió como objetivo general: fundamentar la manera en que los presupuestos de la prospectiva jurídica y la utilización del análisis de impacto regulatorio, coadyuvan a la concreción de la autonomía municipal en Cuba. Fueron utilizados los métodos: dialéctico materialista, análisis y crítica de fuentes, hermenéutico, sistémico-estructural, jurídico-doctrinal y análisis de documentos. Como principales resultados se propone la utilización del análisis de impacto regulatorio, como herramienta de la prospectiva jurídica en el campo del Derecho patrio, en lo específico para la determinación de las normas necesarias para la autonomía municipal; y la elaboración de escenarios para la creación normativa.
Palabras clave:
Prospectiva jurídica, impacto regulatorio, autonomía municipal.

ABSTRACT
In a globalized and complex world, such as today's, it is necessary for the Law to know and use a vital tool for the construction of its regulations: the analysis of regulatory impact, which becomes an instrument of legal prospective. The general objective was defined: to base the way in which the presuppositions of the legal prospective and the use of the analysis of regulatory impact, contribute to the concretion of municipal autonomy in Cuba. Methods were used: dialectical materialist, analysis and criticism of sources, hermeneutic, systemic-structural, legal-doctrinal and analysis of documents. As main results, the use of the regulatory impact analysis is proposed, as a tool of legal prospective in the field of National Law, specifically for the determination of the necessary norms for municipal autonomy; and the elaboration of scenarios for the creation of regulations.
Keywords:
Legal perspective, regulatory impact, municipal autonomy.
Mola hidatiforme parcial: a propósito de un caso
Authors: Cabrera-Miñán Graciela de Jesús , Guerrero-Jiménez Carmen Victoria , Feijóo-Villa Nohelia Maricela 
Published: December 2022

La enfermedad trofoblástica gestacional (ETG) está compuesta por un conjunto de patologías poco comunes asociadas al embarazo, que van desde benignas hasta malignas; se ha descrito como varios procesos benignos y malignos poco habituales, derivados de una proliferación anormal del trofoblasto de la placenta humana, esta agrupa un conjunto de lesiones benignas como la mola hidatiforme y la neoplasia trofoblástica gestacional. La mola hidatiforme es una patología obstétrica poco común, consiste en un embarazo anormal caracterizado por la degeneración hidrópica de las vellosidades coriales e hiperplasia trofoblástica, con una presentación clínica que amerita hacer un correcto uso de las pruebas diagnósticas disponibles, especialmente la ecografía y el Doppler, de forma temprana en la gestación, para establecer su diagnóstico oportuno, lo que va a mejorar favorablemente el pronóstico; además de la realización de la histología, estudios genéticos moleculares serían claves para ayudar en la vía diagnóstica. Su tratamiento de elección es la evacuación uterina y el seguimiento estricto con gonadotropina coriónica humana (hCG), específicamente de los niveles de β-hCG, fundamental para el diagnóstico precoz de la neoplasia trofoblástica gestacional. La enfermedad trofoblástica (ETG) de alto riesgo se trata con quimioterapia multifarmacológica, con o sin cirugía complementaria para la extirpación de focos resistentes de la enfermedad o radioterapia para las metástasis cerebrales.
Palabras clave:
Enfermedad trofoblástica; mola hidatiforme; gonadotropina coriónica.

ABSTRACT
Gestational trophoblastic disease (GTD) is made up of a set of uncommon pathologies associated with pregnancy, ranging from benign to malignant; It has been described as several unusual benign and malignant processes, derived from an abnormal proliferation of the trophoblast of the human placenta, this groups a set of benign lesions such as hydatidiform mole and gestational trophoblastic neoplasia. Hydatidiform mole is a rare obstetric pathology, consisting of an abnormal pregnancy characterized by hydropic degeneration of the chorionic villi and trophoblastic hyperplasia, with a clinical presentation that warrants proper use of available diagnostic tests, especially ultrasound and Doppler , early in pregnancy, to establish its timely diagnosis, which will favorably improve the prognosis; In addition to performing histology, molecular genetic studies would be key to help in the diagnostic pathway. Its treatment of choice is uterine evacuation and strict monitoring with human chorionic gonadotropin (hCG), specifically of β-hCG levels, essential for early diagnosis of gestational trophoblastic neoplasia. High-risk trophoblastic disease (TGD) is treated with multidrug chemotherapy, with or without adjuvant surgery to remove resistant foci of disease, or radiation therapy for brain metastases.
Keywords:
Trophoblastic disease; hydatidiform mole; chorionic gonadotropin.
Evaluación y uso de estrategias de aprendizaje autónomo de lenguas extranjeras a nivel superior
Authors: Pérez-Palafox Viviana , Chong-Barreiro María Cruz , Cáceres-Mesa Maritza Librada , Moreno-Tapia Javier 
Published: December 2022

Los procesos de enseñanza y aprendizaje de lenguas extranjeras están presentes en la educación superior, de manera que la evaluación es una parte fundamental. La apropiación del inglés como lengua extranjera se considera indispensable para el progreso de la vida académica y profesional. En este entendido, el desarrollo de estrategias de aprendizaje autónomo es crucial, puesto que le permiten al estudiante lograr el dominio del idioma de forma independiente. Del mismo modo, las instituciones de educación superior miden el nivel de dominio de las lenguas extranjeras a través de pruebas, las cuales se alinean a los estándares establecidos por el Marco Común Europeo de Referencia para las Lenguas (MCER). Por otro lado, cada institución de educación superior establece sus propios criterios de evaluación del proceso de aprendizaje del inglés, el cual es considerado un factor que incide en el logro de dominio de la lengua.
Palabras clave:
Aprendizaje autónomo, idioma inglés, lenguas extranjeras.

ABSTRACT
The teaching and learning processes of foreign languages ​​are part of higher education, so evaluation is a key part. The acquisition of English as a foreign language is considered essential for the progress of academic and professional life. So the development of autonomous learning strategies is crucial, since they allow the student to achieve mastery of the language independently. Furthermore, higher education institutions measure the level of language proficiency through tests, which are aligned with the standards established by the Common European Framework of Reference ​​(CEFR). On the other hand, the evaluation of the English learning process in higher education is a factor that affects the achievement of language acquisition.
Keywords:
Autonomous learning, English language, foreign languages.
Evaluación agronómica de 3 variedades de maíz (Zea mays L.) en las condiciones edafoclimáticas de la finca “El Porvenir” del consejo popular “La Coronú”, Contramaestre
Authors: Cutiño-Mendoza Amanda , Vuelta-Lorenzo Daniel Rafael , Molina-Lores Lilian Barbara , Vargas-Batis Belyani , Fernández-Hechavarría Madeleine , Mustelier-Ocle Maria Caridad 
Published: December 2022

El presente trabajo se llevó a cabo en la finca “El Porvenir”, perteneciente al Consejo Popular La Coronú en el municipio de Contramaestre, provincia Santiago de Cuba. El objetivo del presente estudio consistió en determinar el comportamiento agronómico de tres variedades de maíz (Zea Mays L.) que mantenga una adecuada adaptación frente a las condiciones edafoclimáticas existentes en la zona. Se utilizó un diseño de bloques al azar, con cuatro réplicas; las parcelas tuvieron un área de 20 m2 sobre un suelo pardo sialítico mullido sin carbonato. Se evaluaron indicadores de crecimiento, desarrollo y rendimiento en las variedades Criollo, Tusón y Canilla a las que se le realizó un análisis de varianza simple con la utilización de la prueba de rangos múltiples de medias mediante la Prueba de Duncan p=0,05 %. Los resultados mostraron al evaluar los indicadores del crecimiento y desarrollo del cultivo que estos no difieren para las tres variedades objeto de estudio, sin embargo, la variedad Canilla mostró el mejor rendimiento con 5.3 tha-1. En el análisis económico se logró reducir el costo unitario en la variedad Canilla, siempre inferior al resto de las variedades estudiadas, con el mayor valor de la ganancia.
Palabras clave:
Evaluación, variedades, maíz, agronómico, edafoclimáticas.

ABSTRACT
The present work was carried out in the "El Porvenir" farm, belonging to the popular council of La Coronú in the municipality of Contramaestre, province of Santiago de Cuba in the period from September 2018 to February 2019. The objective of this study was to determine the agronomic behavior of three varieties of corn (Zea Mays L.) that maintains an adequate adaptation to the edaphoclimatic conditions existing in the area. A randomized block design was used, with four replicas; the plots had an area of 20 m2 on a soft sialitic brown soil without carbonate. Growth, development and yield indicators were evaluated in the Criollo, Tusón and Canilla varieties, which were subjected to a simple variance analysis with the use of the multiple range of means test using the Duncan test p = 0.05%. The results showed when evaluating the growth and development indicators of the crop that these do not differ for the three varieties under study. The Canilla variety shows yields of the 5.3 tha-1. In the economic analysis, the unit cost in the Canilla variety was reduced, always lower than the rest of the varieties studied whit the best performance.
Keywords:
Evaluation, varieties, maize, agronomic, edaphoclimatic.
The Relationship between Fibroblast Growth Factor-23, Insulin-Like Growth Factor-1, Bone Mineral Density, Insulin Resistance, and Hyperandrogenemia in Polycystic Ovary Syndrome
Authors: ÇİFTEL Enver , ÇİFTEL Serpil , KILIÇLI Fatih 
Published: December 2022

Aims: The aim of this study was to find out the association between the Fibroblast Growth Factor-23 (FGF-23), Insulin-Like Growth Factor-1 (IGF-1), androgens, insulin resistance (IR), and bone mineral density (BMD) in patients with PCOS (Polycyctic Ovary Syndrome) and healthy controls is presented.
Materials and Methods: The FGF-23, IGF-1, and Homeostatic Model Assessment for Insulin Resistance were evaluated in 47 patients with PCOS and 26 healthy females, and BMD was evaluated only in the PCOS group. Then these parameters were compared between groups, according to the presence of IR and hyperandrogenemia.
Results: The mean FGF-23 was 137.55± 75.42 and 414.81 ± 53.02 (pg/ml), and mean IGF-1 was 28.41 ± 99.69 and 244.26 ± 58.99 (ng/ml) in patients with PCOS and healthy controls, respectively. In PCOS group, the FGF-23 was more significantly decreased in those with IR and amenorrheic. DEXA scores were found to be similar in PCOS group in terms of hyperandrogenemia and IR.
Conclusions: Our results revealed that FGF-23 levels decreased in patients with PCOS, which was particularly significant in patients with IR. According to our findings; the low level of FGF-23 in the PCOS group with IR suggests that this marker may also be associated with the complications of PCOS, but to clarify this hypothesis, this marker needs to be investigated.
Pathological Prognostic Features and Analysis of Renal Cell Carcinoma
Authors: ÖZTÜRK Sena , ÇELİKGÜN Serkan , YELDİR Neşe 
Published: December 2022

Renal cell carcinomas is 2-3% of all adult cancers. Kidney cancer is currently the seventh most common cancer in men and the tenth most common in women (1). There were 19,3 million new cancer diagnoses and 10 million cancer deaths worldwide in 2020 (2).
Survival in renal cell carcinomas has a strong correlation with the stage of diagnosis. 5-year survival in stage 1 tumors is 93%, 72,5% in cases with local lymph node metastases and 12% in metastatic carcinomas cases (3). There is an inverse correlation between age / tumor size and survival. Metastatic lymph node, tumor necrosis and adipose tissue invasion are associated with poor prognosis (4).
The study is including 179 renal cell carcinoma cases. The clinical and pathological datas of these cases were retrospectively analyzed from the Cumhuriyet University Hospital patient system.
The distribution sex of cases are 111 males (62%) and 68 females (38%). The mean age of the 179 cases was 58,5±11,9 years (range of 21-90). The mean tumor diameter is 5,7±3,4 (range of 1-19 cm). The nuclear grades of cases are 53,1% with low grade and 46,8% with high grade.
Radical nephrectomies were evaluated for vascular invasion, ureter invasion, capsule/adipose tissue invasion, lymph node metastasis and adrenal gland metastasis.
There is a statistically significant relationship between nuclear grade and vein invasion, microvascular invasion, capsule/adipose tissue invasion (p
Characterizing Stream Reaches Occupied by Eastern Hellbender (Cryptobranchus alleganiensis alleganiensis): Insights from A Previously Undocumented Western North Carolina Stream Population
Authors: Levine Alexander , Williams Lori A. , Gillette David 
Published: December 2022

Abstract
The Eastern Hellbender (Cryptobranchus alleganiensis alleganiensis) is a large aquatic salamander found in cool, highly oxygenated rivers and streams of the eastern United States. Hellbender populations have been steeply declining over the past century, and they are a protected species in many states, including North Carolina where they are listed as a species of special concern. North Carolina contains over 2,000 waterways that could potentially support hellbender populations. It is vital to survey these waterways to better understand the distribution of the Eastern Hellbender and the environmental factors necessary to support populations. Although small streams could potentially act as refugia for both larval and adult hellbenders, most surveys have focused on large rivers, generally using substrate composition and cover rock presence as site selection determinants. In early summer of 2013, we surveyed Bent Creek, a small (25.3 km2) catchment in the Pisgah National Forest beginning at the confluence with the French Broad River and concluding upstream to the Lake Powhatan dam. We documented four adult Eastern Hellbenders, including two captures and two tactile encounters/escapes. These represent the first records for C. a. alleganiensis in this catchment. In October 2013, we compared the number of cover rocks, water temperature, dissolved oxygen and substrate composition of three occupied and three unoccupied stream reaches. Although temperature and dissolved oxygen did not vary among reaches, occupied stream reaches had coarser substrates and a much higher occurrence of cover rocks than unoccupied reaches. Our findings suggest that commonly used surveying techniques relying on potential cover rocks and substrate composition are effective methods for selecting survey sites. Future research could examine whether the Eastern Hellbender population at Bent Creek is, or has the potential to become, a viable breeding population, as well as assessing population size upstream from Lake Powhatan. Suitability of stream conditions to consistent larval recruitment should also be evaluated. Our findings suggest that smaller streams such as Bent Creek can support viable populations of C. a. alleganiensis, and that restricting surveys to larger watersheds has the potential to miss important populations of this imperiled species.
Isolation and Identification of Fungi Associated with Avocado Pear (Persea americana Mill)
Authors: Frances Ejimofor, Chiamaka , Enoch Nwakoby, Nnamdi , Johnson Oledibe, Odira , Eziamaka Afam-Ezeaku, Chikaodili , Ann Mbaukwu, Onyinye 
Published: December 2022

This study's objective is to separate and identify harmful fungus from spoiled avocado pears. Healthy avocado pear fruits were delivered to the lab and left to rot on a lab bench after being purchased from Awka, Nnewi, and Ihiala. Potato dextrose agar (PDA) and SDA agar were used to test the fruits for the presence of fungal infections that cause deterioration. According to the findings, PDA media exhibit greater growth than SDA, and ther45 x 102 CFU/g).e was no statistically significp > 0.005ference (p>0.005) between the fungal counts of the avocado and pear samples collected from the three different sites, with the Eke Awka market sample showing the highes48 x 102 CFUcount (48x102cfu/g), followed by the Total Market47 x 102 CFUample (47x102cfu/g), and the Nnewi market sample showing the lowest fungal count (45x102cf Based on their colonial and physical traits, the fungus responsible for the fruit deterioration was identified. The investigation also revealed that a total of 5 isolates of fungus from fruits, including Aspergillus spp., Penicillium spp., Rhizopus sp., Fusarium spp., and Candida spp., were collected. Of them, isolates of Aspergillus niger species were found most commonly (36%). Rhizopus species and Candida were next, each with an infection incidence of 18%, while Fusarium solani and Penicillium digitatum were the least common (141%). Aspergillus niger, one of the identified fungi, was the least harmful and produced the least amount of fruit rot. R. stolonifer, Fusarium solani, Candida tropicalis, and Penicillium digitatum were the least pathogenic and caused the most fast disintegration of treated fruits in 3-5 days. This study has demonstrated that fungus is to blame for fruit rotting. This study has demonstrated that fungus is to blame for fruit rotting. Producing, preparing, and preserving foods like fruit salads must be done as quickly and hygienically as possible using high-quality tools, products, and materials since fruits are typically infested by harmful fungus.