bluuebunny/crossref_metadata_2025_split huggingface dataset:
Home-based transcranial direct current stimulation in mild neurocognitive disorder due to possible Alzheimer’s disease. A randomised, single-blind, controlled-placebo study
Authors: Satorres Encarnacion , Escudero Torrella Joaquin , Real Elena , Pitarque Alfonso , Delhom Iraida , Melendez Juan C. 
Published: January 2023

IntroductionMild neurocognitive disorder (mNCD), a pre-dementia stage close to Mild Cognitive Impairment, shows a progressive and constant decline in the memory domain. Of the non-pharmacological therapeutic interventions that may help to decelerate the neurodegenerative progress, transcranial direct current stimulation (tDCS) shows beneficial effects on the learning curve, immediate recall, immediate verbal memory and executive functions. The purpose of this research was to study the effect of tDCS on general cognition, immediate and delayed memory and executive functions by comparing an active group with a placebo group of mNCD patients.MethodsParticipants were 33 mNCD due to possible AD, randomly assigned to two groups: 17 active tDCS and 16 placebo tDCS. Ten sessions of tDCS were conducted over the left dorsolateral prefrontal cortex. Several neuropsychological scales were administered to assess the primary outcome measures of general cognitive function, immediate and delayed memory and learning ability, whereas the secondary outcome measures included executive function tests. All participants were evaluated at baseline and at the end of the intervention. Mixed ANOVAs were performed.ResultsSignificant effects were obtained on general cognitive function, immediate and delayed memory and learning ability, with increases in scores in the active tDCS group. However, there were no significant effects on executive function performance.ConclusionThe present study demonstrated the effectiveness of tDCS in an active tDCS group, compared to a placebo group, in improving general cognition and immediate and delayed memory, as previous studies found. Taken together, our data suggest that tDCS is a simple, painless, reproducible and easy technique that is useful for treating cognitive alterations found in neurodegenerative diseases.
Developing Stable Freeze-Dried Functional Ingredients Containing Wild-Type Presumptive Probiotic Strains for Food Systems
Authors: Prapa Ioanna , Nikolaou Anastasios , Panas Panayiotis , Tassou Chrysoula , Kourkoutas Yiannis 
Published: January 2023

Designing stable dried functional food ingredients and foods containing live probiotic cultures maintaining high viable cell loads at the time of consumption is a challenge for the industry. The aim of the present study was the development of stable freeze-dried functional food ingredients with enhanced shelf-life during long storage. Zea flakes, pistachios, and raisins were used as immobilization supports for the wild-type presumptive probiotic strains Pediococcus acidilactici SK and Lactiplantibacillus plantarum F4, while L. plantarum B282 was used as a reference strain. Cell survival was monitored during storage at room and refrigerated temperatures for up to 6 months. Levels of freeze-dried cultures were maintained up to 7.2 logcfu/g after 6 months storage at room temperature and up to 8.5 logcfu/g at refrigerator temperature, in contrast to free cell levels that ranged <7 logcfu/mL, suggesting the positive effects of immobilization and freeze-drying on cell viability. Of note, levels of freeze-dried immobilized P. acidilactici SK cells on zea flakes and pistachios remained stable after 6 months of storage at 4 °C, ranging 8.1–8.5 logcfu/g (survival rates 98.2 and 99.7%, respectively). The technology developed presents important advantages for the maintenance of cell viability during storage, assuring stability of ready-to-use functional food ingredients that could be directly incorporated in food systems.
Molecular Characterization of Three Apple Geminivirus Isolates in Crabapples Detected in Inner Mongolia, China
Authors: Sun Ping-Ping , Zhang Lei , Xu Xiao-Zhao , Zhu Mo , Zhang Bin , Li Zheng-Nan 
Published: January 2023

Apple geminivirus 1 (AGV) in the genus Maldovirus of the family Geminiviridae was first identified infecting apple trees in the year 2015 in China. In this work, we characterized three isolates of the AGV in the Chinese pearleaf crabapple (Malus asiatica) in Inner Mongolia Autonomous Region. The viruses were detected by Illumina sequencing and its existence was confirmed by reverse transcription-polymerase chain reaction (RT-PCR) amplification of an AGV fragment. Between the three AGV isolates and the initially characterized AGV isolate PL2015, the nucleotide sequence identities of the complete genome ranged from 91.2 to 91.7%, of the coat protein gene (V1) ranged from 95.4% to 97.3%, and of the replicase gene (C1) ranged from 87.3% to 88.0%. Phylogenetic analysis indicated that the three isolates formed a monophyletic group together with the AGV, separated from the current genera in the family Geminiviridae. This is the first description of the AGV infecting crabapples.
El recurso agua, su importancia a través de procederes didácticos en contenidos matemáticos
Authors: Álvarez Pardo Elen Dolores , Abreu Alonso Oslaidys , Crespo O´Relly Nismel 
Published: January 2023

El recurso agua es una prioridad, una necesidad de primer orden para garantizar el desarrollo económico y social, sobre todo, para la salud y supervivencia de la especie humana en todo el planeta. Lograr un nivel de educación ambiental mediante un proceso de enseñanza-aprendizaje desarrollador es nuestro propósito, sin embargo, este proceso en la actualidad presenta insuficiencias. Se realizó el estudio de las condiciones teóricas, metodológicas y prácticas en que se desarrolla, a fin de alcanzar la preparación adecuada sobre el conocimiento del agua y su importancia para su desempeño ulterior. Los métodos aplicados permitieron corroborar el estado actual, así como la revisión de documentos, sobre el contenido para establecer los fundamentos teóricos y metodológicos de la investigación. Los resultados obtenidos a través de la aplicación de estos métodos permitieron la elaboración de informes y realizar las valoraciones cualitativas correspondientes. En la preparación alcanzada, mediante la ejecución de procederes didácticos a través de un sistema de actividades se identifican: que estos manifestaron en todo momento motivación e interés por lograr su preparación, lo que les permitió el cambio en su modo de actuación. Elevaron el nivel de compromiso, interés y creatividad, se nutrieron de conocimientos para su aplicación presente y futura.
The Acupressure Combination Points BL32 and L14 With Points BL32 And SP6 on Labor Pain in Active Phase
Authors: Mujahidah Saadah , Megawati Megawati , Hapsari Shindi 
Published: January 2023

ABSTRACTLabor pain that is not resolved will cause hyperventilation so that the need for oxygen increases, blood pressure increases, and reduced intestinal motility and vesikaurinaria. This situation stimulates an increase in catecholamines which disrupts uterine contractions resulting in uterine inertia. Labor pain due to psychic responses and physical reflexes. Acupressure is used to treat pain. Acupressure can affect the intensity of pain. This study was to determine the effect of giving Acupressure Combination of Points BL32-L14 with BL32-Sp6 on Active Phase I Labor Pain in PMB Sukatmi Setrokalangan Kudus. This type of research was a Quasy experiment with a two-group pre-post test design. The sampling technique used was accidental sampling with a sample size of 24 respondents divided into two groups (12 interventions and 12 controls). The normality test used the Shapiro-Wilk test, data analysis used the Wilcoxon and Mann-Whitney tests. Acupressure BL32 and L14 for pain (p 0.03), Acupressure BL32 and Sp6 got p 0.002. Comparison of BL 32-Li4 acupressure with Bl32-Sp6 got p 0.590. There is an effect of Acupressure BL32 and L14 on labor pain, and there is an effect of Acupressure BL32 and Sp6 on labor pain. There was no difference between BL 32-Li4 and Bl32-Sp6 on labor pain. Keywords : acupressure; active phase; bl32-li4; bl32-sp6; labor pain ABSTRAKNyeri persalinan yang tidak teratasi akan menyebabkan hiperventilasi sehingga kebutuhan oksigen meningkat, tekanan darah meningkat, dan motilitas usus berkurang dan vesikaurinaria. Keadaan ini merangsang peningkatan katekolamin yang mengganggu kontraksi uterus sehingga terjadi inersia uterus. Nyeri persalinan karena respon psikis dan refleks fisik. Akupresur digunakan untuk mengobati rasa sakit. Akupresur dapat mempengaruhi intensitas nyeri. Penelitian ditujukan untuk mengetahui pengaruh pemberian Akupresur Kombinasi Titik BL32-L14 dengan BL32-Sp6 terhadap Nyeri Persalinan Aktif Fase I di PMB Sukatmi Setrokalangan Kudus. Jenis penelitian ini adalah Quasy eksperimen dengan desain two-group pre-post test design. Teknik pengambilan sampel yang digunakan adalah accidental sampling dengan jumlah sampel 24 responden yang terbagi menjadi dua kelompok (12 intervensi dan 12 kontrol). Uji normalitas menggunakan uji Shapiro-Wilk, analisis data menggunakan uji Wilcoxon dan Mann-Whitney. Akupresur BL32 dan L14 untuk nyeri (p 0,03), Akupresur BL32 dan Sp6 didapatkan p 0,002. Perbandingan akupresur BL 32-Li4 dengan Bl32-Sp6 didapat p 0,590. Ada pengaruh Akupresur BL32 dan L14 terhadap nyeri persalinan, dan ada pengaruh Akupresur BL32 dan Sp6 terhadap nyeri persalinan. Tidak ada perbedaan antara BL 32-Li4 dan Bl32-Sp6 pada nyeri persalinan. Kata kunci : akupresur; fase aktif; bl32-li4; bl32-sp6; nyeri persalinan
Potensi Antihiperglikemik Ekstrak Kulit Buah Semangka (citrullus lanatus linn.) terhadap Diabetes Mellitus Melalui Penghambatan Aktivitas Enzim Alfa Glukosidase
Authors: Syachriyani Syachriyani , Firmansyah Firmansyah 
Published: January 2023

Diabetes Mellitus merupakan gangguan metabolisme endokrin yang ditandai dengan abnormalitas kadar glukosa dalam aliran darah karena aktivitas gaya hidup yang tidak sehat. Pendekatan terapeutik yang dapat digunakan untuk mengobati penyakit Diabetes Mellitus yaitu dengan cara penghambatan enzim yang berhubungan dengan penyerapan glukosa di tubuh, seperti enzim alfa-glukosidase. Tujuan dari penelitian adalah untuk mengetahui potensi antihiperglikemik ekstrak Kulit Buah Semangka melalui penghambatan aktivitas enzim alfa-glukosidase dengan menentukan persen inhibisi dan IC50 ekstrak Kulit Buah Semangka sehingga dapat dimanfaatkan sebagai antidiabetes terhadap Diabetes Mellitus. Ekstrak Kulit Buah Semangka diperoleh dengan cara maserasi menggunakan pelarut Etanol 96 %. Enzim alfa-glukosidase yang digunakan pada penelitian ini berasal dari Saccharomyces cerevisae dan p-nitrofeni –?-D-glukopiranosid (pNPG) yang berfungsi sebagai substrat. Ekstrak Kulit Buah Semangka dibuat dengan variasi konsentrasi 20, 40, 60, 80 dan 100 ppm.. Aktivitas enzim diukur berdasarkan hasil absorbansi p-Nitrofenol yang absorbansinya terukur pada panjang gelombang 410 nm menggunakan microplate reader. Hasil pengujian inhibitor ekstrak Kulit Buah Semangka konsentrasi 20 ppm. 40 ppm, 60 ppm dan 80 ppm terhadap enzim alfa-glukosidase menunjukkan rata-rata persen inhibisi 7,904 %, 17,937 %, 24,757 %, 32, 894 % dan 41,840 % sedangkan baku Akarbose diperoleh persen inhibisi 50,115 %, 60,000 %, 69,152 %, 73,837 % dan 79,179 %. Nilai IC50 ekstrak Kulit Buah Semangka 120,212 ppm dan baku Akarbose 13,055 ppm, Hal ini menunjukkan bahwa ekstrak Kulit Buah Semangka dapat memberikan efek penghambatan (inhibitor) terhadap enzim alfa-glukosidase.
Fo Guang Shan’s Expansion in the Religious Market of Thailand
Authors: Su Guiyu , Liu Yaoping 
Published: January 2023

As one of the prominent Mahayana Buddhist institutions from Taiwan, Fo Guang Shan (FGS) entered the religious market of Thailand as early as the 1990s. Its influence has grown tremendously among the local Chinese communities and Thai society. Despite this, there is a dearth of scholarship dedicated to FGS’s market expansion in Theravada-dominated Thailand. Through a SWOT analysis, this paper explores FGS’s marketing strategy for the Thai religious market. The findings suggest that FGS bears certain strengths, such as its appealing humanistic Buddhist doctrine, gift-giving networking skills and its strong emotional bonds with the Chinese communities in Thailand. These strengths have brought and will continuously provide FGS with opportunities for further expansion. However, FGS’s weakness is always there and obvious, given its foreign and non-mainstream nature and questionable legitimacy of existing as a Buddhist institution (or temple) in Thailand. All this has already caused threats to FGS’s missionary clergies and sanctuaries, mainly based in the Bangkok area, not to mention the growingly fierce competition from its Thai Theravada and local-born Mahayana counterparts.
An Analysis of Inflectional Morphemes in a Short Story “The Child’s Story” by Charles Dickens
Authors: Ifadloh Nur , Najerin Muhammad Rizky , Nufus Zahratun , Ulum Miftakhul 
Published: January 2023

This study aims to determine the inflectional morpheme contained in the short story entitled "The Child's Story" by Charles Dickens. The analysis shows that there are 108 inflectional morphemes found in the short story "The Child's Story". There are 35 plural nouns “-s”, “-es” with 32.5% percentage as the most dominant inflectional morphemes found in this story. Next, possessive nouns “-'s”, “-s'” and comparative adjectives “-er” both show 2 data (1.8%), superlative adjectives “-est” shows 3 data (2.7%), 3rd person singular/present tense “-s” shows 4 data (3.7%), verb past tense “-ed”/”-d” shows 29 data (26.9%), Present participle “-ing” shows 32 data (29.7%), past participle verb “-en” shows 1 data (0.9%). In addition, Inflectional does not change the grammatical category of words consisting of "-s, -'s, -er, -est, -s, -ed, -ing, and -en". The suffix “-s” means plural. The suffix “-'s”, “-s'” means possessive. The ending “-er” means comparative. The suffix “-est” means superlative. The ending “-ed” means past. The ending “-ing” means current (continuous). The ending “-en” means participle.
Keywords: Morphology, Words, Inflectional, Morphemes, Suffixes.
Perancangan Data Warehouse Sistem Penerimaan Siswa Baru Menggunakan Online Analytical Processing (OLAP) di TK IT Mutiara
Authors: Azizah Qonita , Masriah Masriah , Atmojo Wahyu Tisno 
Published: January 2023

Peningkatan jumlah siswa pada TK IT Mutiara membuat sekolah kesulitan dalam melakukan pengelolaan data pendaftaran sehingga harus membutuhkan waktu untuk mendapatkan informasi. Pembuatan aplikasi OnLine Analytical Processing (OLAP) Data Warehouse dapat membantu mengekstrak dan memudahkan dalam mencari informasi penting dari beberapa sistem informasi yang berbeda. Metode penelitian yang dilakukan adalah kualitatif dengan teknik perolehan data wawancara dengan seorang narasumber di TK IT Mutiara dan studi pustaka melalui jurnal yang relevan dengan topik penulis dan juga menggunakan metode nine step Kimball. Tujuan penelitian ini adalah untuk merancang sistem yang memudahkan kepala sekolah untuk melakukan analisis terhadap data siswa baru menggunakan Aplikasi OLAP Data Warehouse. Hasil penelitian ini adalah terciptanya aplikasi OLAP Data Warehouse yang dapat memberikan kemudahan kepada kepala sekolah dalam melakukan analisis terhadap data siswa baru sehingga dapat membantu proses pengambilan keputusan, serta dapat menampilkan bentuk laporan yang mudah dibaca dan dipahami.
Penggunaan make a match untuk meningkatkan pengetahuan dan sikap ibu dalam pencegahan ispa pada balita
Authors: Husna Anis Rosyiatul , Kusumawardani Novianty , Marini Gita , Nasrullah Dede 
Published: January 2023

Penyakit ISPA merupakan salah satu penyakit yang sering dialami oleh anak balita. Orang tua menganggap hal ini biasa terjadi pada usia tersebut. Kurangnya pengetahuan ibu dalam mengenali dan memberikan perawatan menyebabkan anak terlambat dalam mendapatkan pengobatan, sehingga berlanjut pada kondisi yang lebih parah yaitu pneumonia. Banyak metode yang digunakan perawat untuk memberikan informasi dan pemahaman kepada masyarakat tentang ISPA. Pendekatan edukasi dengan Make a Match diharapkan dapat meningkatkan pengetahuan ibu dalam mencegah ISPA pada balita. Pengabdian ini dilaksanakan di posyandu panggul, Sidoarjo dengan jumlah peserta 20 ibu yang memiliki anak balita dan dilaksanakan selama 2 minggu. Pelaksanaan kegiatan pengabdian ini menggunakan pendekatan kelompok. Metode yang digunakan dalam pengabdian ini adalah Make a Match. Hasil pengabdian menunjukkan terjadi peningkatan pengetahuan baik dari 5 orang menjadi 18 orang. Kesimpulan, pendidikan kesehatan dengan metode Make a Match dapat digunakan sebagai salah satu metode edukasi untuk meningkatkan pengetahuan ibu dalam pencegahan ISPA pada balita.

Acute Respiratory Infectionis (ARI) is a disease that is often experienced by children under five. Parents think this is common at that age. The lack of knowledge of mothers in recognizing and providing care causes children to be late in getting treatment, so that it continues in a more severe condition, namely pneumonia. Many methods are used by nurses to provide information and understanding to the public about the disease. The educational approach with Make a Match is expected to increase mother's knowledge in preventing ARI in toddlers. This service was carried out at the Pelvic Posyandu, Sidoarjo with 20 participants, mothers with toddlers and carried out for 2 weeks. The implementation of this service activity uses a group approach. The method used in this service is Make a Match. The results of the service showed an increase in good knowledge from 5 people to 18 people. In conclusion, health education using the Make a Match method can be used as an educational method to increase mothers' knowledge in preventing ARI in toddlers.
Pendampingan desa penambangan menuju desa inklusi ramah perempuan, anak, dan budaya
Authors: Prasetyowati Irma , Setyari Agustina Dewi , Eriyanti Linda Dwi , Rohman Hermanto 
Published: January 2023

Desa penambangan dinilai memiliki banyak inovasi terutama berkenaan dengan pengembangan literasi dan digitalisasi. Namun, berdasarkan hasil evaluasi serta diskusi yang telah dilakukan bersama Pemerintah desa capaian tersebut masih belum berjalan optimal pasca pendampingan. Kegiatan pengabdian masyarakat ini bertujuan untuk mendampingi Desa Penambangan Kecamatan Curahdami kabupaten Bondowoso guna mewujudkan desa inklusif yang ramah anak, perempuan, dan budaya melalui program inovasi desa dengan mengoptimalkan potensi desa yang sudah ada. Metode pengabdian masyarakat ini terdiri dari tahap persiapan dan tahap pendampingan. Observasi awal dilakukan menggunakan dua pendekatan yaitu pendekatan partisipatoris, serta wawancara (diskusi). Sedangkan tahap pendampingan dilakukan dengan Focus Group Discuss( FGD) penyusunan partisipatif desain kebijakan yang inovatif dan terintegratif. Hasil pengabdian masyarakat ini diperoleh pelaksanaan pendampingan Desa Penambangan telah memenuhi target yang sesuai dengan strategi dalam upaya mewujudkan Desa ramah perempuan dan peduli anak (DRPPA). Luaran pelaksanaan pendampingan ini adalah terbentuknya regulasi Perdes/peraturan kepala Desa terkait rencana aksi Desa Penambangan menuju Desa ramah anak, perempuan dan budaya.

Penambangan villages are considered to have many innovations, especially with regard to the development of literacy and digitalization. However, based on the evaluation results and discussions that have been carried out with the village government, the results have not run optimally after the assistance. This community service activity aims to assist Penambangan Village, Curahdami District, Bondowoso Regency to create an inclusive village that is child-, women- and cultural-friendly through a village innovation program by optimizing the potential of existing villages. This community service method consists of a preparatory stage and a mentoring stage. Initial observations were made using two approaches, namely the participatory approach, as well as interviews (discussion). While the mentoring phase is carried out by means of a Focus Group Discussion (FGD) for participatory preparation of innovative and integrated policy designs. The results of this community service were obtained by the implementation of the Penambangan Village assistance that had met the targets according to the strategy in an effort to create a women-friendly and child-caring village (DRPPA). The output of this mentoring implementation is the formation of Perdes regulations/Village head regulations related to the Penambangan Village action plan towards a child, women and cultural friendly village.
Factors Affecting the Completeness of Completion of Inpatient Medical Records in Hospitals
Authors: Devhy Ni Luh Putu , Purwanti Ika Setya 
Published: January 2023

Medical record is a document that contains patient data consisting of identity, history of examination and treatment of patients. Medical records must be filled out completely because they can be used as a legal basis if something unexpected happens during a health action. Completeness of medical records can be used as a support to improve health services. Based on the results of previous studies, it was found that only 74% of the completeness of the RM from the name of the action indicator. This literature review aims to determine the factors that affect the completeness of filling out medical records.
Methods: The method used in this article is a literature review, the search for articles in this LR uses a google scolar, with the keywords "completeness factors", AND "medical records" AND "hospitalization". The articles found in the search were 262 articles, then re-evaluated according to the inclusion and exclusion criteria that had been set so that finally 5 articles were available that could be reviewed.
Results: Factors that affect the completeness of filling out medical records are man, method, material, money Man, money and methode are factors which effect uncomplitement of medical records, so that recommended to make standard operating procedure (SPO) in doing medical records then for giving motivation to the health worker in filling medical records we can giving present and clear sanctions for them.
Conclusion: Man, money, materials, and methods are factors that can affect the incompleteness of medical records, so it is recommended to make Standard Operating Procedures (SOP) in carrying out medical record activities and socialize them on an ongoing basis, then to motivate health workers in filling out RMs, prizes can be given and clear sanctions.
SENSITIVITAS DAN SPESIFISITAS METODE RAPID TEST ANTI-HBs TERHADAP ELISA
Authors: Putri Gela Setya Ayu , Santosa Budi 
Published: January 2023

Hepatitis B merupakan penyakit inflamasi dan nekrosis sel hati yang disebabkan oleh infeksi virus hepatitis B (VHB). Kehadiran anti-HBs merupakan faktor penting dalam diagnosis dan prognosis infeksi VHB. Rapid test adalah salah satu metode pemeriksaan selain ELISA untuk mendeteksi adanya anti-HBs, lebih praktis dalam penggunaan dan ekonomis. Tujuan penelitian ini untuk mengetahui nilai sensitivitas dan spesifisitas rapid test anti-HBs Intec® terhadap metode ELISA sebagai gold standar. Penelitian ini merupakan studi observasional menggunakan metode uji diagnostik. Populasi penelitian ini adalah mahasiswa D4 Analis Kesehatan FIKKES Universitas Muhammadiyah Semarang semester tujuh post vaksinasi hepatitis B sejumlah 32 orang untuk didapatkan serum darah. Analisis statistik dilakukan uji Mc Nemar. Hasil pemeriksaan dengan rapid test yaitu positif 26 sampel (81,2%), dan negatif 6 sampel (18,8%). Hasil pemeriksaan dengan ELISA yaitu reaktif 27 sampel (84,4%), dan nonreaktif 5 sampel (15,6%). Kesimpulan akhir yaitu Rapid test anti-HBs Intec® memiliki nilai sensitivitas dan spesifisitas yang sangat baik dengan persentase sensitivitas 96,3% dan persentase spesifisitas 100%. Tidak terdapat perbedaan yang bermakna pada sensitivitas dan spesifisitas metode rapid test dan ELISA (p= 1,000) sehingga Rapid test anti-HBs Intec® dapat digunakan sebagai skrining untuk pemeriksaan anti-HBs.