bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detailed View of the Seismogenic Structures and Processes of the 2022 Bayan Har Intraplate Earthquake Swarm on the East Margin of the Qinghai–Tibet Plateau
Authors: Su Jinrong , Lei Xinglin , Li Jun , Huang Chunmei 
Published: June 2023

Abstract
At 16:03 on 9 June 2022 (UTC), an Mw 5.5 earthquake followed by several Mw&gt;4 events, including the largest event of Mw 5.8 within a few hours, occurred in the Maerkang area near the Caodeng Hot Spring Town, located in the south-central part of the Bayan Har plate on the eastern margin of the Qinghai–Tibet plateau. The earthquake swarm allows understanding the tectonic stress environment of the Bayan Har plate and is an example of a typical moderate-to-strong intraplate earthquake swarm. This article comprehensively analyzes the detailed seismogenic fault structure of the swarm by means of precise hypocenter relocation, focal mechanism inversion for Mw&gt;4 earthquakes, inversion of the tectonic stress field in different regions of the Bayan Har plate, tidal strain calculation, and seismicity statistics. The results show that the swarm was not directly related to the nearby mapped Songgang fault, but rather resulted from the successive activation of a series of unknown faults. The precise hypocenter distribution, together with focal mechanism solutions of major earthquakes, illuminates five major seismogenic faults with conjugate relationships and stepover. Spatial and temporal migration of hypocenters, stress transfer, and tidal correlations demonstrate that cascade triggering, afterslip, and overpressured fluid might have jointly played a role in causing the earthquake swarm. As an output of this research, a set of verifiable datasets are provided as a basis for further in-depth research.
Prosthetic rehabilitation with implant-supported fixed prosthesis in a completely edentulous patient: A clinical report
Authors: Wilson Teena , Nair Vivek V , K Harshakumar , V Prasanth 
Published: June 2023

To present clinical strategies for prosthetic rehabilitation of completely edentulous patients using immediate-loading basal implants.A 58-year-old female patient was referred to the Department of Prosthodontics for restoration of her completely edentulous maxilla and mandible with a fixed full-arch implant-prosthetic rehabilitation. Since the patient lacks adequate bone in the posterior maxilla and is not willing to undergo a removable interim prosthesis, an immediate loading protocol along with 8 single-piece basal implants, including 2 pterygoid implants in the maxillary arch and 6 single-piece basal implants in the mandibular arch, was selected as the treatment option, followed by an acrylic provisional restoration. Four months later, a definitive fixed implant-supported prosthesis was delivered.This treatment strategy may be considered for rehabilitating patients with atrophic ridges demanding fixed provisional prostheses throughout the healing period and can be employed even in immediate implant placement after extraction.
Vanished Open Access Journals; Why Preservation Is Needed
Authors: Grams Kathy 
Published: June 2023

A Review of:Laakso, M., Matthias, L., & Jahn, N. (2021). Open is not forever: A study of vanished open access journals. Journal of the Association for Information Science & Technology, 72(9), 1099–1112. https://doi.org/10.1002/asi.24460
Objective – To determine the number of open access journals that have vanished from the web and to summarize their publishing lifespan, geographical and disciplinary characteristics.
Design – A descriptive research study.
Setting – The internet and internet archive.
Subjects – Open access journals.
Methods – To identify vanished open access (OA) journals, vanished was defined by the authors as “a journal that published at least one volume as immediate OA after which production ceased, and the journal, together with the published full-text documents, disappeared from the web.” If the journal content partially existed, it would be considered as vanished if <50% was available during 12 months of data collection which occurred September 2019–September 3, 2020. In 2020, the OA journal list was created by searching Directory of Open Access Journals (DOAJ), Ulrichsweb Global Serials Directory, and Scopus title lists. The list was cross-referenced with database records from DOAJ from 2010–2012, 2012–2014, and 2014–2019; Ulrichsweb title lists from May 24, 2012, and July 3, 2018; and Scopus title lists from February 2014 and April 2018, to determine the missing titles. Previous research by the primary author and two peers, and previous publications, also contributed to the list of vanished journals. Data was collected manually, and duplicates were removed. Authors searched the Keepers Registry to be sure that the journal content was not preserved or accessible. Only titles with an ISSN number were kept in the final list. The authors then searched indexing databases and Google to find the vanished journal’s website, then accessed the website through the Internet Archive's Wayback Machine to gather the information such as the year founded, last year of publication, last year available online, language, country, affiliation, and academic discipline.
Main Results – Authors identified 154 completely vanished journal titles and 20 partially vanished journal titles, to total 174 verified titles. Journals originated from 47 countries; the majority were published in English (n=137), and most were from North America, Europe and Central Asia (n=109). Social sciences and humanities domain represented 52.3% or 91 titles, and the last publication year of most titles occurred between 2010 and 2014 (n=110). The authors estimated the average time of the last published issue to the last available time on the internet to be within 1 year for 68 titles and within 5 years for 144 titles.
Conclusion – Although the results represent a small number of the available OA journals at the time of the study (1.2%), it reinforces the authors’ theme that “open is not forever” and raises concern of the potential loss of scholarly work.
Idaratu Tathbiqu Al-Manhaju 2013 ‘Ala Ta’limi Al-Lughati Al-‘Arabiyati Fii Al-Madrasati At-Tsanawiyati Al-Islamiyati Bima’hadi Al-Ikhlashiyati Sisik As-Syarqiyati Lumbuk Al-Wustho
Authors: . Hilman , Azis Abdul 
Published: June 2023

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
Discourse Markers In The Essay Produced By EFL Students Of Mandalika University Of Education
Authors: Kamarudin  
Published: June 2023

The aim of this research was to investigate the types of discourse markers, and to elaborate on the types of discourse markers, and identify the reason why they used these types of discourse markers in the essay text. It used descriptive qualitative research. The subjects were the sixth-semester students of the English Language Department of Mandalika University of Education consisting of 19 students that were chosen out randomly. The data were in the form of the student’s essay writing text that was analyzed by using Fraser Taxonomy (1999). The result reveals that out of 8 types of discourse markers, there were 7 types that occurred in the essay text written by students.
Rahanat Tawzif al-Lughah al-Arabiyah fi Maydan al-Siyahah
Authors: Benouargla Nadia 
Published: June 2023

?? ???? ???? ?????? ???? ?? ???? ?? ??? ??? ?????? ???? ???? ???????? ????? ????????: ????? ???? ???? ??????? ??? ????? ????? ???????. ???? ??? ??????? ???????? ????????? ?????. ??? ?? ??????? ??????? ???? ???? ???? ???????? ?????? ???????? ???? ???? ???? ??????? ???????? ?? ????? ????? ?? ??????? ?????? ????????. ??? ????? ?????? ?? ????? ??? ??????? ?? ????? ?????? ???? ???? ????? ?? ?????? ???? ?? ???? ????? ?????? ??? ?? ???? ??????? ?????? ???? ??? ????? ??? ????? ???? ????? ????? ??? ???? ????????? ???? ?? ??? ????????? ???? ??????? ???? ?????? ?????? ????? ?????? ?????? ??? ????? ????? ?????? ??????? ??????? ?? ????? ????? ???? ????? ?????? ???? ?? ?????? ????? ?????? ??????? ??????? ????????.
Ta’lim al-Lughah al-‘Arabiyah fi Indunisiya: Al-Waqi’ wa al-Mustaqbal
Authors: Busyairi Lalu Ahmad 
Published: June 2023

???? ????? ??????? ?? ????????? ???????? ???????? ?????????? ??? ?? "????????" (Pesantren) ??? ???? ???? ?????? ???? ????? ?????? ???????. ??? ???? ??? ????? ????? ??? ??????? ?? ????? ????? ?????? ??????? ???? ?? ???? ??? "????? ?? ???? ????" ?????? ?? "????????" ?? ????? ????? ?????? ??? ?? ???? ????? ??????? ?? ?????? ??????? ??????? ??? ????? ?? ????? ????? ???????? ????? ???? ?? "????????" ??? "????????" ???? (???? ????) ?? ???? ?? "????????" ??????. ??? ????? ??????? ????????? ??????? (?????????????) ???? ???? ????? ???? ?????? ??????? ?? ????? ???? ??????? ??? ??????? ?? ????? ????????? ?? ????? ????? ??????? ?? ???? ??????? ??????? – ??? ???? ??????? ????????? – ?? ??????? ???????? ???????? ???????? ??????? ??????? ????? ??? ??????? ??????? ?? ???? ??????? ??? ????? ??????? ???????? ?????? ?? ????? ?????? ????? ???? ???????? ???????? ??????? ???????? ??? ???? ??? ?????? ??????? ????? ??? ??????? ????? ??????? ????? ??? ?????? ?? ??????? ???? ??????? ??? ?? ??? ????? ??????? ?? ????????? ????? ???????.
Impact of dialysate bicarbonate concentration on the progression of coronary artery calcification in patients undergoing haemodialysis: a prospective, interventional study
Authors: Oka Machiko , Ohtake Takayasu , Ishioka Kunihiro , Mochida Yasuhiro , Maesato Kyoko , Moriya Hidekazu , Hidaka Sumi , Kobayashi Shuzo 
Published: June 2023

AbstractBackground This interventional study aimed to assess the relationship between high and low bicarbonate dialysis and quantitatively measure coronary artery calcification (CAC) using multi-slice computed tomography (MSCT) in patients undergoing haemodialysis (HD). Methods We used two dialysates with different bicarbonate concentrations (Kindaly 3E®and Carbostar PⓇ) to evaluate the effects of dialysate bicarbonate concentration on CAC progression. Kindaly 3EⓇwas an acetic-acid dialysate with a dialysate calcium (dCa) concentration of 2.5 mEq/L and a bicarbonate concentration of 25 mmol/L. Carbostar PⓇwas a citric-acid dialysate with a dCa concentration of 3.0 mEq/L and a bicarbonate concentration of 35 mmol/L. The Kindaly 3EⓇdialysate was used for all patients for the first 6 months of the study period, and the Carbostar PⓇdialysate was used for all patients for the second 6 months of the study period. Results Fifty-three patients undergoing HD underwent MSCT at study initiation, whereas 45 underwent follow-up MSCT 6 and 12 months later to evaluate the CAC score (CACS). The serum calcium and phosphorus levels did not change significantly during the study period. Intact parathyroid hormone levels were significantly increased, although both bone alkaline phosphatase and tartrate-resistant acid phosphatase-5b levels were significantly decreased after 6 months of Carbostar P®use. Conclusions Pre-HD bicarbonate levels and CACS changes over a 6-month period (ΔCACS) were significantly higher with Carbostar P®than with Kindaly 3EⓇ. Trial RegistrationThe study was conducted in accordance with the Declaration of Helsinki and approved by the Ethics Committee of Tokushukai Medical Group (TGE01018-008 22/5/2018; TGE-1018-024; 29/11/2018). The University hospital Medical Information Network-Clinical trials registry (UMIN-CTR) number is UMIN000035085 (30/11/2018).
Efficient prediction of milling distortion using inversely-identified inherent strains
Authors: XU YANG , Huang Xiaomei , Chen Yun , Ye Chao , Hou Liang 
Published: June 2023

Abstract
Predictive milling distortion has been widely used to optimize milling design and process. Inherent strains method (ISM) applies plastic strains calculated from small-scale thermo-mechanical simulations to large-scale models to assess residual deformation in less time. In this paper, ISM is proved feasible in milling process by theoretical and experimental analysis. Moreover, a novel method called inverse identification is proposed to obtain milling inherent strain efficiently. To verify the proposed method, two milling cases are presented to evaluate its accuracy in distortion prediction. In addition, comparisons with the thermo-mechanical model and traditional ISM model indicate that the inversely-identified inherent strains can significantly reduce the simulation time at the premise of similar precision, which is practical to be applied in industrial applications.
Distinct Local and Global Functions of Aβ Low-Threshold Mechanoreceptors in Mechanical Pain Transmission
Authors: Gautam Mayank , Yamada Akihiro , Yamada Ayaka , Wu Qinxue , Kridsada Kim , Ling Jennifer , Yu Huasheng , Dong Peter , Ma Minghong , Gu Jianguo , Luo Wenqin 
Published: June 2023

Abstract
The roles of Aβ low-threshold mechanoreceptors (LTMRs) in transmitting mechanical hyperalgesia and in alleviating chronic pain have been of great interest but remain contentious. Here we utilized intersectional genetic tools, optogenetics, and high-speed imaging to specifically examine functions of SplitCre labeled Aβ-LTMRs in this regard. Genetic ablation of SplitCre-Aβ-LTMRs increased mechanical pain but not thermosensation in both acute and chronic inflammatory pain conditions, indicating their modality-specific role in gating mechanical pain transmission. Local optogenetic activation of SplitCre-Aβ-LTMRs triggered nociception after tissue inflammation, whereas their broad activation at the dorsal column still alleviated mechanical hypersensitivity of chronic inflammation. Taking all data into consideration, we propose a new model, in which Aβ-LTMRs play distinctive local and global roles in transmitting and alleviating mechanical hyperalgesia of chronic pain, respectively. Our model suggests a new strategy of global activation plus local inhibition of Aβ-LTMRs for treating mechanical hyperalgesia.
The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons
Authors: Saha Orthis , de Farias Ana Melo , Pelletier Alexandre , Siedlecki-Wullich Dolores , Landeria Bruna , Gadaut Johanna , Carrier Arnaud , Vreulx Anaïs-Camille , Guyot Karine , Bonnefond Amélie , Amouyel Philippe , Kilinc Devrim , Queiroz Cláudio , Delahaye Fabien , Lambert Jean-Charles , Costa Marcos 
Published: June 2023

Abstract
Bridging Integrator 1 (BIN1) is the second most important Alzheimer’s disease (AD) risk gene, but its physiological roles in neurons and its contribution to brain pathology remain largely elusive. In this work, we show that BIN1 plays a critical role in the regulation of calcium homeostasis, electrical activity, and gene expression of glutamatergic neurons. Using single-cell RNA-sequencing of cerebral organoids generated from isogenic BIN1 wild-type (WT), heterozygous (HET) and homozygous knockout (KO) human-induced pluripotent stem cells (hiPSCs), we show that BIN1 is mainly expressed by oligodendrocytes and glutamatergic neurons, like in the human brain. Both HET and KO cerebral organoids show specific transcriptional alterations, mainly associated with ion transport and synapses in glutamatergic neurons. We then demonstrate that BIN1 cell-autonomously regulates gene expression in glutamatergic neurons by using a novel protocol to generate pure culture of human-derived induced neurons (hiNs). Using this system, we also show that BIN1 plays a key role in the regulation of neuronal calcium transients and electrical activity via its interaction with the L-type voltage-gated calcium channel Cav1.2. BIN1 KO hiNs show reduced activity-dependent internalization and higher Cav1.2 expression compared to WT hiNs. Pharmacological blocking of this channel with clinically relevant doses of nifedipine, a calcium channel blocker, partly rescues neuronal electrical and gene expression alterations in BIN1 KO glutamatergic neurons. Further, we show that transcriptional alterations in BIN1 KO hiNs affecting biological processes related to calcium homeostasis are also present in glutamatergic neurons of the human brain at late stages of AD pathology. Together, these findings suggest that BIN1-dependent alterations in neuronal properties could contribute to AD pathophysiology and that treatment with low doses of clinically approved calcium blockers should be considered as an option to dampen disease onset and progression.
The Relationship between the Gut Microbiome and Resistance Training: A Rapid Review
Authors: Wagner Adam , Kapounková Kateřina , Struhár Ivan 
Published: June 2023

Abstract
The human gut microbiome is attracting increasing attention because of its overall effect on human health. A number of reviews have explored the effect of physical activity on the gut microbiome, though these have mostly focused only on endurance or combined types of physical activity. This study aims to describe the effect of resistance or strength training on the gut microbiome of a healthy or unhealthy population. This rapid review follows the guidelines of the Cochrane Rapid Reviews Guidance along with PRISMA. A review of the literature was carried out using articles indexed by PubMed, Scopus, and Web of Science published in the last 12 years. None of the seven studies included find significant change in the gut microbiome in terms of bacterial taxa composition or overall diversity, though the results show that resistance training might decrease the zonulin level and increase mucin production and thereby reduce inflammation in the gut. Interestingly, two studies point to a gut-muscle axis connection and this is discussed in our paper. However, due to the small number of existing studies and certain methodological disagreements, it was hard to find a consensus on the relationship between the gut microbiome and resistance training.
Psychometric Evaluation of the Chinese Version of the Multidimensional Competitive Orientation Inventory
Authors: Wang Yuqian , Orosz Gabor , Chen Xi , Miao Chengguo , Li Yansong 
Published: June 2023

Abstract
This study examined the psychometric properties of the Chinese version of the Multidimensional Competitive Orientation Inventory (Ch-MCOI) in adults from Mainland China. A total of 1121 participants (50.6% male; M = 28.86, SD = 8.70) were recruited for this study. All participants completed the Chinese versions of the MCOI, the Connor-Davidson Resilience Scale (CD-RISC), the Warwick-Edinburgh Mental Well-being Scale (WEMWBS), the Almost Perfect Scale-Revised (APS), and the Frost Multidimensional Perfectionism Scale (MPS-f). A subsample of 239 participants (50.6% male; M = 32.04, SD = 8.13) completed the Ch-MCOI again after a two-week interval to assess test–retest reliability. Exploratory Structural Equation Modeling (ESEM) yielded a four-factor structure (hyper-competitive orientation, self-developmental competitive orientation, anxiety-driven competition avoidance, and lack of interest toward competition), which was further validated by confirmatory factor analyses with a satisfactory fit. Furthermore, test–retest reliability, internal consistency, and concurrent validity were also acceptable. Our findings suggest that the Ch-MCOI could be a reliable and valid instrument for assessing the adaptive and maladaptive facets of competitive orientations in the Chinese-speaking population.
Efficacy of Copper Nanoparticles Encapsulated in Soya Lecithin Liposomes in Treating Breast Cancer Cells (MCF-7) In Vitro
Authors: Ahmed Shaimaa A. , Gaber Mohamed H. , Salama Aida A. , Ali Said A. 
Published: June 2023

Abstract
Cancer is one of the leading causes of death which attracted the attention of the scientific world to search for efficient methods for treatment. With the great development and regeneration of nanotechnology over the last 25 years, various nanoparticles in different structures, shapes and composites provide good potential for cancer therapy. The purpose of this study aims to investigate the effect of Copper nanoparticles (CuNPs) as a drug model for cancer treatment either in their free form or encapsulated in Soy lecithin liposomes (SLP) from plant origin as a cheap source of lipids. CuNPs were by the chemical reduction method then loaded to SLP through the thin film hydration method. The drug model Cu/SLP was successfully combined. The characteristics of the free CuNPs, liposomes, and the combined form, zeta potential, size distribution, drug encapsulation efficiency (EE%), drug release profile, Fourier transform Infrared (FTIR), transmission electron microscopy (TEM) were checked followed by in vitro study on breast cancer cell line Mcf-7 as a model for cytotoxicity evaluation. The optimal Cu/SLP had a particle mean size of 81.59 ± 14.93 nm, a negative zeta potential of -50.7 ± 4.34 mV, the loaded CuNPs showed EE% of 78.9%, and a drug release profile for about 50% of the drug was released after 6 h, and FTIR analysis are recorded. The cytotoxicity assay showed that the IC50 of Cu/SLP is smaller than that of free CuNPs. These results give clear evidence of the efficacy of using the combined Cu/SLP than CuNPs alone as a model drug carrier prepared from plant origin against cancer medically and economically.
A Mutual Authentication Quantum Key Agreement protocol based on Bell Pair
Authors: Rao B. Devendar , Jayaraman Ramkumar 
Published: June 2023

Abstract
Identification and key negotiation between trusted users play a pivot role in generating a session key. The existing protocol uses quantum resources with memory for authentication process but the storage time for qubit is limited. A new mutual authentication quantum key agreement protocol was proposed using Bell pair and the pre-shared key act as the basis for applying bell state measurement without storing the qubit. Security of the proposed protocol depends on inappropriate applying the Bell measurement in different basis leading to entanglement swapping. The participant is able to create a fair session key for each communication and mutually authenticate each identity. The key negotiation and authentication phases of the proposed mutual authentication quantum key agreement protocol have demonstrated that it is unconditional secure.
Uncoupling of lifespan and reproductive tradeoffs by dietary methionine and one-carbon metabolism
Authors: Wei Fangchao , Liu Shiyu , Liu Juan , Allen Annamarie , Reid Michael , Locasale Jason 
Published: June 2023

Abstract
Aging has been proposed to be a consequence of reproductive ability and longevity thus occurs as a tradeoff with organismal reproduction1, 2. Lifespan extending interventions generally at the expense of fertility3. How this principle extends to nutrition and metabolism is not understood. We considered dietary methionine restriction (MR) that is linked to one carbon metabolism as well as to Mediterranean or plant-based diets4 ,5 and known to influence cancer6, metabolic health7, and longevity3, 8. Using a chemically defined diet (CDD) we developed for Drosophila melanogaster, we found that MR-mediated lifespan extension indeed occurs at the expense of reproduction. A survey of the nutritional landscape in the background of MR revealed that folic acid, a vitamin linked to one carbon metabolism, surprisingly was the lone nutrient that restored reproductive defects without compromising lifespan extension. In vivo isotope tracing, metabolomics and flux analysis identified the Tricarboxylic (TCA) cycle and redox coupling as the primary determinants of MR benefits. Interestingly, the fecundity defect occurred through altered sperm function and its restoration by folic acid supplementation also restored sperm mitochondrial metabolism. Together these findings suggest that dietary interventions connected to specific changes in metabolism can separate adverse effects that may occur by enhancing longevity.