bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural, nutritional, and functional properties of amaranth protein and its application in the food industry: A review
Authors: Zhang Xin , Shi Jiajia , Fu Yidan , Zhang Tianyi , Jiang Lianzhou , Sui Xiaonan 
Published: March 2023

AbstractDue to population and environmental concerns, more sustainable proteins are needed as alternatives to traditional proteins, including meat, milk, and soy proteins. Amaranth protein has been considered as a complete protein that is also gluten‐free and balanced in amino acid composition. Amaranth protein is rich in bioactive peptides, and its hydrolysis products have been demonstrated to be potential in preventing several diseases such as cardiovascular disease, cancer, and diabetes. Amaranth protein is high in albumin, glutenin, and globulin, whereas the variability in albumin and glutenin content is dependent on the geography and variety of amaranth. In the food industry, amaranth protein is currently used in nutritionally fortified foods, gluten‐free foods, and food protein‐based films. Due to its excellent nutritional and bifunctional properties, amaranth protein has shown a great potential in functional foods and meat analogues. This review provides an overview of several properties of amaranth protein, including nutrition, bioactivity, structure, as well as its applications in the food industry and prospects. By reviewing the above properties of amaranth protein, it is considered as one of the promising sustainable alternative protein sources for future foods.
Effectiveness of 0.1% Mometasone Furoate under Hydrocolloid Dressing Versus 0.1% Mometasone Furoate in Patients with Lichen Simplex Chronicus
Authors: Lo Hiu Lai , Ip Fong Cheng 
Published: March 2023

Abstract
There was a lack of high-quality, evidence-based treatment for lichen simplex chronicus (LSC). Topical steroid under hydrocolloid dressing treatment was investigated mostly in observational studies without investigation of the cost-effectiveness and the methodology of application also varied without standardisation. To investigate the cost-effectiveness of topical steroid under hydrocolloid dressing in the treatment of moderate to severe lichen simplex chronicus (LSC). The study aimed to provide a clear methodology that was replicable. A single-blinded randomized controlled trial was carried out to compare the efficacy of 0.1% mometasone furoate cream with or without hydrocolloid dressing in patients suffering from moderate to severe LSC. Physician Global Assessment (PGA) score, Eczema Area and Severity Index (EASI) individual components score were assessed by a Dermatologist through clinical photos at week 0, 2, and 4. Pruritis Numerical Rating Scale (PNRS) was rated. Forty adult patients were recruited. The group with hydrocolloid dressing showed superior treatment efficacy. 20 out of 20 patients benefited from the hydrocolloid dressing with topical steroid while only 6 out of 20 patients benefited from topical steroid alone at week 2 regarding PGA. Similar result was obtained at week 4. Extra HK$ 132 was needed for each patient in hydrocolloid with topical steroid group. The number needed to treat (NNT) was 1.43 (95% CI: 1.42–1.44) at week 2 and 1.42 (95% CI: 1.41–1.44) at week 4 regarding PGA score improvement of ≥2. NNT analysis supported the cost-effectiveness of adjunctive hydrocolloid dressing usage as the first-line treatment in patients with moderate to severe LSC. This study added evidence to LSC treatment with a detailed and reproducible methodology.
Microstructural Analysis and Corrosion Behavior of a Titanium Cenosphere Composite Foam Fabricated by Powder Metallurgy Route
Authors: Majumdar Dibyendu Dutta , Sahu Shrishty , Mondal Dehi Pada , Roychowdhury Amit , Jha Amol Kumar , Ghosh Manojit 
Published: March 2023

AbstractThis study examines the influence of cenosphere particle size and sintering parameters on the microstructure and electrochemical behavior of Ti‐cenosphere composite foam fabricated by powder metallurgy route. Cenosphere has been added as a space holder material to develop Ti composite foam because of its abundant availability and low cost. Ti (particle size between 250 μm and 350 μm) and cenosphere (with a varying particle size of <150 μm, 150 μm–200 μm and >200 μm) in the ratio of 75 : 25 (wt %) were compacted using 100 MPa of applied pressure and sintering temperatures of 1000 and 1200 °C with sintering time ranging from 2 to 6 h at a heating rate of 25 °C/min. A defect‐free microstructure with the uniform dispersion of cenosphere particles in the Ti matrix was observed with the cenosphere particles in the size range of 150–212 μm at a sintering temperature of 1000 °C for 4 h. The porosity content in the syntactic foam varied from 34 to 50 % and decreased with increasing sintering time and temperature. Based on a detailed study of corrosion behavior in Hank's solution, the composite foam with cenosphere particles in the size range of 150–212 μm and sintered at 1000 °C for 4 h showed the highest corrosion resistance.
Exploring a supramolecular gel to in‐situ crystal fabrication from the low molecular weight gelators: a crystal engineering approach towards microelectronic device application
Authors: Dhibar Subhendu , Pal Baishakhi , Karmakar Kripasindhu , Kundu Sandip , Bhattacharjee Subham , Sahoo Rupam , Mehebub Rahaman SK. , Dey Dhananjay , Pratim Ray Partha , Saha Bidyut 
Published: March 2023

AbstractA novel functional supramolecular gel (SA‐MEA) has been produced through the mixing of succinic acid and monoethanolamine directly in DMF medium under ambient conditions. The semi‐solid and viscoelastic nature of mechanically stable SA‐MEA gel has been established through the rheological analysis. The major chemical components of the gel are confirmed by EDX elemental mapping, while FESEM microstructural analysis investigates the morphological patterns of the gel. The gel gives rise to crystalline materials at room temperature and in the absence of external stimuli. Single‐crystal diffraction study of the in‐situ generated crystals shows the existence of different supramolecular synthons involving the hydrogen‐bonding interactions (N−H⋅⋅⋅O and O−H⋅⋅⋅O) leading to the formation of graph set motifs. These structural building blocks provide the stability to hold the overall molecular framework of SA‐MEA gel. Moreover, the contribution of O⋅⋅⋅H/H⋅⋅⋅O contacts plays a crucial role in this gel formation, which is established from the Hirshfeld surfaces along with linked 2D fingerprint patterns of the plot for both molecular components. Additionally, the SA‐MEA gel‘s supramolecular structure exhibits electrical conductivity, which was exploited to construct an electronic device with a metal‐semiconductor (MS) junction. Analyses of the gel‘s electrical properties were done in‐depth. Inclusive, this work demonstrates that the SA‐MEA gel may be used to create a semi‐conductive microelectronic device, such as a Schottky barrier diode.
Computational Study of the Adsorption of Small Gas Molecules on Pillar[5]arenes
Authors: Duy Ho Quoc , Rauls Eva 
Published: March 2023

AbstractThe anthropogenic carbon dioxide (CO2) that is the main cause of the greenhouse effect has become subject to many studies of gas capture, storage, and separation. P[n]A‐based supramolecular organic frameworks (SOF) have emerged as a promising candidate for capturing and separation of CO2. Experimental studies show high adsorption rates and selectivity for CO2 over other gases such as methane (CH4) and nitrogen (N2). [Advanced Materials 26, 7027 (2014)] However, a full understanding of CO2 adsorption in P[n]A is still missing. Using density functional theory (DFT) based calculations, we found that CO2 can be adsorbed by P[5]A in different positions. The most favorable adsorption position is within the cavity of P[5]A. The CO2 molecule adsorbs by forming hydrogen bonds or by π‐π interaction with the benzene rings of P[5]A. Also CH4 and N2 can be physisorbed by P[5]A, but with lower binding energies, which can be explained by the weaker quadrupole moments and polarizabilities of CH4 and N2. Our investigations are the basis for targeted design and optimization of a potential application of P[5]A in CO2 capture, storage, and separation.
Hydrogen‐bond Peculiarities in Nitrilotris‐(Methylenephosphonato)‐Three‐aqua‐Iron(II) from XRD Experiment and DFT Calculation
Authors: Dobysheva Lyudmila V. , Chausov Feodor F. 
Published: March 2023

AbstractNitrilotris‐(Methylenephosphonato)‐Three‐aqua‐Iron(II) (FeNTP) is a linear organic‐inorganic coordination polymer forming on the steel surface as an anti‐corrosion coating. The compound was studied earlier experimentally and theoretically using ab‐initio DFT calculations. Here, the peculiarities of the bonds of hydrogen atoms, within and between the polymer chains, forming the three‐dimensional network of the coating, are discussed and compared to those in other compounds including water. The effect of Fe magnetic moment on the hydrogen bonds is studied. It is shown that in organometallic compounds, the magnetic state of magnetic atoms M affects the total polymer volume both through the M‐nearest neighbor distances and through the H‐bonding lengths, the change in the latter can even prevail over the former.
Pentanoate‐Tethered Artemisinin‐Isatin Hybrids with Antileukemic Potential
Authors: Xu Zhi , Chen Linzhi , Xu Dan 
Published: March 2023

AbstractA series of novel pentanoate tethered artemisinin‐isatin hybrids 6 a–d and 7 a–m were synthesized and evaluated their activity against CCRF‐CEM, K562 and K562/ADR leukemia cell lines as well as normal human peripheral blood mononuclear cells (PBMCs) by MTT assay. In particular, hybrid 7 b (IC50: 2.30 and 2.77 μM) exhibited highest activity against CCRF‐CEM and K562 cells, and the activity was not inferior to these of adriamycin (IC50: 4.89 μM) and vorinostat (IC50: 3.83 μM) against K562 cells, whereas hybrid 7 g (IC50: 0.62 μM) was more potent than adriamycin (IC50: 4.89 μM) and vorinostat (IC50: 3.83 μM) against K562/ADR cells. Moreover, the two hybrids (IC50: >100 μM) displayed non‐cytotoxicity towards normal PBMCs cells, and the selectivity index values were >11.02, indicating their excellent selectivity and safety profiles. Thus, hybrids 7 b and 7 g could act as potential anti‐leukemic candidates and were worthy of further preclinical evaluations.
Piperazine‐ and Pyrazole‐Based Heterocyclic Scaffold Derivatives Connected with Urea and Thiourea for Anti‐Inflammatory Activity
Authors: Bhargavi Dodda , Konduri Srihari , Prashanth Jyothi , Sireesha Malladi , Prabhakara Rao Koya 
Published: March 2023

AbstractA couple of series of heterocyclic‐based urea and thiourea derivatives, connected with a hybrid scaffold skeleton containing pyrazole and piperazine ring moieties, were achieved. In this study, a total of fifteen new compounds were synthesized by reacting 1‐(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐yl)piperazine hydrochloride with carbamides and thiocarbamides. All the fifteen newly synthesized compound structures were confirmed by 1H & 13C NMR and FTIR spectroscopy, ESI mass spectrometry, CHNS analysis and HPLC chromotograms. Moreover, the structures of N‐allyl‐4‐(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐yl)piperazine‐1‐carbothioamide and 4‐(3‐methyl‐1‐phenyl‐1H‐pyrazol‐5‐yl)‐N‐(4‐nitrophenyl)piperazine‐1‐carbothioamide were also confirmed by single‐crystal X‐ray diffraction analysis. Further, as per the objective of this work, all these fifteen newly synthesized compounds were screened for anti‐inflammatory activity. The majority of the compounds displayed moderate‐to‐good anti‐inflammatory activity. The anti‐inflammatory activity study was also correlated with molecular docking studies using the receptor Cyclooxygenase‐2.
An Ultra‐Stable Electrode‐Solid Electrolyte Composite for High‐Performance All‐Solid‐State Li‐Ion Batteries
Authors: Huang Yuqin , Gao Panyu , Zhang Tengfei , Zhang Xiang , Xia Guanglin , Fang Fang , Sun Dalin , Guo Zaiping , Yu Xuebin 
Published: March 2023

AbstractThe low ionic and electronic conductivity between current solid electrolytes and high‐capacity anodes limits the long‐term cycling performance of all‐solid‐state lithium‐ion batteries (ASSLIBs). Herein, this work reports the fabrication of an ultra‐stable electrode‐solid electrolyte composite for high‐performance ASSLIBs enabled by the homogeneous coverage of ultrathin Mg(BH4)2 layers on the surface of each MgH2 nanoparticle that are uniformly distributed on graphene. The initial discharge process of Mg(BH4)2 layers results in uniform coverage of MgH2 nanoparticle with both LiBH4 as the solid electrolyte and Li2B6 with even higher Li ion conductivity than LiBH4. Consequently, the Li ion conductivity of graphene‐supported MgH2 nanoparticles covered with ultrathin Mg(BH4)2 layers is two orders of magnitude higher than that without Mg(BH4)2 layers. Moreover, the thus‐formed inactive Li2B6 with strong adsorption capability toward LiBH4, acts as a stabilizing framework, which, coupled with the structural support role of graphene, alleviates the volume change of MgH2 nanoparticles and facilitates the intimate contact between LiBH4 and individual MgH2 nanoparticles, leading to the formation of uniform stable interfaces with high ionic and electronic conductivity on each MgH2 nanoparticles. Hence, an ultrahigh specific capacity of 800 mAh g−1 is achieved for MgH2 at 2 A g−1 after 350 cycles.
N‐Heterocyclic Olefin Type Ionic Liquid with Innate Soft Lewis‐Base Character as an Effective Additive for Hybrid Quasi‐2D and 3D Perovskite Solar Cells
Authors: Zhou Zhonggao , Li Lihua , Li Bolun , Li Jing , Liu Tianyong , Huang Xi , Tang Shaobin , Qiu Hongdeng , Cai Wanzhu , Zhang Shiyong , Li Kan , Xu Guohai , Zhen Hongyu 
Published: March 2023

AbstractIn optimizing perovskites with ionic liquid (IL), the comparative study on Lewis acid‐base (LAB) and hydrogen‐bonding (HB) interactions between IL and perovskite is lacking. Herein, methyl is substituted for hydrogen on 2‐position of imidazolium ring of N‐heterocyclic carbene (NHC) type IL IdH to weaken HB interactions, and the resulting N‐heterocyclic olefin (NHO) type IL IdMe with softer Lewis base character is studied in both hybrid quasi‐2D (Q‐2D) and 3D perovskites. It is revealed that IdMe participates in constructing high‐quality Q‐2D perovskite (n = 4) and provides stronger passivation for 3D perovskite compared with IdH. Power conversion efficiency (PCE) of Q‐2D PEA2MA3Pb4I13 perovskite solar cells (PVSCs) is boosted to 17.68% from 14.03%. PCE and device stability of 3D PVSCs enhances simultaneously. Both theoretical simulations and experimental results show that LAB interactions between NHO and Pb2+ take the primary optimization effects on perovskite. The success of engineering LAB interactions also offers inspiration to develop novel ILs for high‐performance PVSCs.
Identification, isolation, and structure elucidation of novel forced degradation products of nelarabine
Authors: Parmar Raghuvirsinh , Rajput Sadhana , Mohan Arivozhi 
Published: March 2023

AbstractThe present study focuses on novel degradation products of nelarabine generated from forced degradation study. In the process, a novel analytical method was developed which was not only compatible with liquid chromatography‐mass spectrometry but also had the efficiency to capture each of the possible degradation products with sufficient separation from the nelarabine peak. Nelarabine was exposed to acidic, alkali, oxidation, photolytic, and thermal stress conditions as recommended by International Conference on Harmonization guidelines. No major degradation was observed under photolytic and thermal conditions however the drug was observed to be significantly degraded under acidic, alkali, and oxidative stress conditions generating a total of nine novel degradation products which are hitherto not been reported in the literature. The major degradation products obtained under acidic and alkali conditions were isolated using preparative high‐performance liquid chromatography and their structure was elucidated using nuclear magnetic resonance spectroscopy and high‐resolution mass spectroscopic studies. Moreover, probable pathways for the formation of these degradation products were also outlined.
Metal‐Organic Framework Composites and Their Derivatives as Efficient Electrodes for Energy Storage Applications: Recent Progress and Future Perspectives
Authors: Wang Teng , Chen Shaoqian , Chen Kai‐Jie 
Published: March 2023

AbstractMetal‐organic frameworks (MOFs) have been important electrochemical energy storage (EES) materials because of their rich species, large specific surface area, high porosity and rich active sites. Nevertheless, the poor conductivity, low mechanical and electrochemical stability of pristine MOFs have hindered their further applications. Although single component MOF derivatives have higher conductivity, self‐aggregation often occurs during preparation. Composite design can overcome the shortcomings of MOFs and derivatives and create synergistic effects, resulting in improved electrochemical properties for EES. In this review, recent applications of MOF composites and derivatives as electrodes in different types of batteries and supercapacitors are critically discussed. The advantages, challenges, and future perspectives of MOF composites and derivatives have been given. This review may guide the development of high‐performance MOF composites and derivatives in the field of EES.
Pasta wastes, as substitute for corn, in the laying Japanese quails diet: Effects on production performance, egg quality and blood biochemistry
Authors: Mohammadi Hamed , Pirsaraei Zarbakht Ansari , Mousavi Seyed Naser , Ghobadi Navvab 
Published: March 2023

AbstractBackgroundAnimal food shortage and finding efficient ways to produce poultry products are getting more and more important issues in the world.ObjectivesThis study was aimed to determine the effect of replacing corn with pasta wastes (0%, 50% and 100%) in the diet on production performance, some blood variables and the egg quality traits of laying quails.MethodsA total of 240 laying quails were allocated into 3 experimental groups with 8 replicates for 8 weeks. Egg production percentage, egg mass, feed intake and also mortality rate and percentage of abnormal eggs, egg quality traits and blood variables were evaluated.ResultsNone of the pasta wastes inclusion had significant effect on egg mass, abnormal egg percentage, mortality rate, yolk diameter, yolk weight, albumen height, yolk index, shell weight percentage, egg shape index and blood parameters (except for triglycerides). Replacing 100% corn with pasta by‐product reduced feed conversion ratio and increased egg weight values. Replacing 100% corn by pasta wastes significantly increased the albumen weight, shell weight and also egg length and width and decreased the Haugh unit. Replacing 50% and 100% corn had a significant increase in yolk height, egg surface area and significantly decreased shell thickness and yolk colour. Overall, 100% replacement of corn by pasta by‐product increased blood triglycerides compared to the 50% group.ConclusionsBased on the result of current experiment, total replacement of corn with pasta wastes could increase the egg weight and also improve feed conversion ratio in the laying quail diets.
An eigenvalue solution for nonlocal vibration of guide supported perfect/imperfect functionally graded power‐law and sigmoid nanobeams on one‐parameter elastic foundation
Authors: Civalek Ömer , Uzun Büşra , Özgür Yaylı Mustafa 
Published: March 2023

AbstractTo the best of the authors' knowledge, this study for the first time, proposes a finite element (FE) model to investigate the size‐dependent vibrational responses of guide supported imperfect functionally graded (FG) nonlocal beams embedded in an elastic foundation in the context of nonlocal elasticity theory (NET). The main objective of this paper is to present a nonlocal FE solution for vibration analysis of imperfect FG nanobeams including nonlocal effect, power‐law distribution function, sigmoid distribution function, even porosity model, uneven porosity model, elastic foundation parameter, and guide support condition. It is considered that perfect/imperfect FG nanobeams are made of silicon carbide (SiC) and aluminum (Al) and that beam properties vary along the height direction. In addition, the nanobeams rest on a one‐parameter elastic foundation and this foundation provides the interaction between the structure and the soil with elastic springs. The frequency values of perfect/imperfect FG power‐law and sigmoid nanobeams obtained by using a nonlocal FE method are shown via tables and figures.
Basic Concepts and Terms
Authors: Winter Alfred , Ammenwerth Elske , Haux Reinhold , Marschollek Michael , Steiner Bianca , Jahn Franziska 
Published: March 2023

AbstractA common terminology is needed when dealing with information systems. Health information systems, as socio-technical subsystems of a healthcare setting, compriss data, information, and knowledge processes as well as the associated actors. They support information and knowledge logistics.When dealing with health information systems and their architecture, we distinguish between concepts such as entities and entity types, computer-based and non-computer-based application components supporting functions, and physical data processing systems. Electronic health records (EHR) are parts of health information systems that collect patient health data from different health care settings. A patient record is the collection of a patient’s health data from a certain facility.Management of health information systems includes planning, directing, and monitoring tasks. The three-layer graph-based metamodel (3LGM2) is a metamodel that supports the management of health information systems. It describes the components of health information system architectures and their relationships among each other at three layers. It consists of the domain layer to describe functions and entity types, the logical tool layer to describe application components, and the physical tool layer to describe physical tools, as well as the inter-layer relationships between the three layers.
Einleitung
Authors: Fischer-Kongtso Satu 
Published: March 2023

ZusammenfassungDie vorliegende Untersuchung befasst sich mit der Frage, wie Deutsche Nation in der deutschen Gesellschaft definiert wird. Dabei verortet sie sich – als ethnologische Arbeit – im empirischen Feld der interdisziplinären Nationalismusforschung. Sie verortet sich des Weiteren – als ethnologische Arbeit – im theoretisch-methodischen Paradigma der interdisziplinären Diskursforschung. Ziel dieses ersten Kapitels ist es, jene doppelte theoretische Verortung zu erörtern. In diesem Sinne widmet sich Abschnitt 1.1 der Begründung des spezifischen Ansatzes der Arbeit und seiner Einbettung in den aktuellen ethnologischen sowie interdisziplinären Forschungsstand. Abschnitt 1.2 schließt daran mit einer inhaltlichen Einleitung in Thema und Fragestellung der Untersuchung an und gibt einen ersten Überblick über ihre zentralen Grundbegriffe sowie die sich daraus ergebende Struktur der Darstellung.