bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Malaysian consensus report on the diagnosis and treatment of Helicobacter pylori infection
Authors: Goh Khean‐Lee , Lee Yeong Yeh , Leow Alex Hwong‐Ruey , Ali Raja Affendi Raja , Ho Shiaw Hooi , Mahadeva Sanjiv , Mohd Said Rosaida Hj , Muthukaruppan Chettiar Raman , Tee Hoi Poh 
Published: March 2023

AbstractHelicobacter pylori is one of the most common chronic bacterial infections in humans and responsible for 90% of duodenal ulcers and 70–90% of gastric ulcers. Despite this, many misconceptions regarding the appropriate diagnostic method and treatment strategies still exist in the Malaysian clinical practice. Under the initiative of the steering committee, an expert panel consisting of nine key opinion leaders in the field of gastroenterology convened to develop a set of consensus statements that are relevant to the Malaysian healthcare practice. The panel members reviewed the current evidence on the management of H. pylori infection, focusing on the best practices that are relevant to the Malaysian population based on clinical experience and published clinical evidence. Using the modified Delphi method, the panel achieved consensus in three areas of H. pylori infection management: indications for testing, diagnosis, and treatment. The panel proposed a set of 19 consensus statements, which were synthesized via two rounds of blinded voting and group discussions. The recommendations provided are relevant to the Malaysian population and can be used as a guide by physicians across various healthcare settings to facilitate appropriate diagnostic testing and treatment of H. pylori infection.
Comparing two durations of medically tailored meals posthospitalization: A randomized clinical trial
Authors: Boxer Rebecca , Drace Melanie L. , Kelly Cheryl , Robinson Rachael , Schwartz Pamela , Ausiello Jenna , Dollar Blythe , Paolino Valerie , Comer Angela , Powers John David , Steiner John F. 
Published: March 2023

AbstractBackgroundMedically tailored meals (MTM) may be beneficial to patients after hospital discharge.ObjectiveTo determine if 2 versus 4 weeks of MTM posthospitalization will improve patient outcomes.DesignRandomized unblinded trial.Settings and ParticipantsSix hundred and fifty patients pending hospital discharge with at least one chronic condition.InterventionOne MTM a day for 2 versus 4 weeks.Main Outcome and MeasuresThe primary outcome was a change from baseline to 60 days in the Hospital Anxiety Depression Scale (HADS). Secondary outcomes measured change in the Katz activities of daily living (ADLs), DETERMINE nutritional risk, and all‐cause emergency department (ED) visits and rehospitalizations.ResultsFrom baseline to 60 days the HADS anxiety subscale changed 5.4–4.9 in the 2‐week group (p = .03) and 5.4–5.3 in the 4‐week group (p = .49); the difference in change between groups 0.4 (p = .25). HADS changed 5.4–4.8 in the 2‐week group (p = .005) and 5.3–5.1 in the 4‐week group (p = .34); the difference in change between groups 0.4 (p = .18). ADL score changed from 5.3 to 5.6 in the 2‐week group (p ≤ .0001) and 5.2–5.5 in the 4‐week group (p ≤ .0001); the difference in change between groups −0.01 (p = .90). The DETERMINE changed in the 2‐week group from 7.2 to 6.4 (p = .0006) and from 7 to 6.7 in the 4‐week group (p = .19); the difference in change between groups 0.5 (p = .13). There was no difference in ED visits and rehospitalizations between groups or time to rehospitalization.ConclusionsDifferent durations of short‐term MTM did not affect patient‐centered or utilization outcomes.
Leaders' political skills and organizational change
Authors: Ouedraogo Noufou , Ouakouak Mohammed Laid , Hewapathirana Gertrude I. 
Published: March 2023

AbstractWe studied the impact of leaders’ political skill on employee support for organizational change and the effect of the latter on change fatigue and change outcomes. Drawing from the theoretical characterization of the political skill construct domain proposed by Ferris et al. (2007), we posited that leaders’ political skill during organizational change plays an important role in garnering employee support for change and, ultimately, in achieving positive change outcomes. To conduct the study, we used survey data collected through SurveyMonkey on 197 participants working in Canadian organizations and used structural equation modeling techniques to analyze the data. We found that two dimensions of leaders’ political skill—their networking ability and apparent sincerity—positively affected employee support for change, which, in turn, positively affected change outcomes. However, neither of the other two dimensions examined (interpersonal influence and social astuteness) had a significant relationship with employee support for change. We also found that employee support for change and change fatigue were not significantly related, although change fatigue itself negatively affected change outcomes. From a theoretical perspective, this study is among the first to empirically test and confirm the impact of different dimensions of leaders’ political skill on employees’ change support. We also contribute theoretical knowledge by showing the detrimental effect of change fatigue on change outcomes. From a practical perspective, our findings imply that change leadership roles should be assigned to people who exhibit networking skills and apparent sincerity. Moreover, change leaders should prioritize seeking and securing employees’ support for change.
Entrepreneurship: Definitions, opportunities, challenges, and future directions
Authors: Ratten Vanessa 
Published: March 2023

AbstractEntrepreneurship as a field of study has many sub‐dimensions due to its usefulness in society, which makes it difficult to gain a holistic understanding of its key elements. The aim of this article is to explore how to define entrepreneurship by focusing on different areas of entrepreneurship in terms of definitions and research opportunities in order to challenge conventional practices. Each area of entrepreneurship is discussed with the goal of exploring new research questions and methodological approaches that are currently lacking in the entrepreneurship discourse and can be refined through future research activity. This enables future research directions to be identified regarding entrepreneurship in general and specific types of entrepreneurship thereby contributing to research and practice about the importance of entrepreneurship in society.
Hospital and surgeon experience and patient health outcomes after coronary artery bypass graft surgery
Authors: Li Jingyun , Bardhan Indranil R. , Sethi Suresh , Ring W. Steves 
Published: March 2023

AbstractThe Hospital Readmissions Reduction Program imposes financial penalties on hospitals with excess readmission rates for various conditions, including coronary artery bypass graft (CABG) surgery. While prior research has focused mainly on hospital‐specific factors and their impact on patient mortality, surgeon risk factors and patient outcomes, such as readmission risk, have received less attention. We study three drivers of CABG readmission risk—hospital and surgeon case volume, variation in surgeon volume, and surgeon familiarity with hospitals. Drawing on unique patient data sets of CABG surgeries spanning 3 years, we study the relationships between hospital and surgeon case volume, readmission risk, and postoperative length of stay (PLOS). We find evidence of an inverted U‐shaped relationship between case volume and readmission risk and a U‐shaped relationship with PLOS. Our results also indicate that surgeon volume variation moderates the relationship between surgeon volume and readmission risk, where readmission risk increases with greater variation in surgeon volume. We observe that the impact of surgeon experience on readmission risk at the focal hospital outweighs their experience at other hospitals. Our study has significant implications for hospital resource management as it highlights the role of surgeon and hospital experience in improving patient outcomes after CABG surgery.
Integrated non‐targeted and targeted metabolomics analysis reveals the mechanism of inhibiting lignification and optimizing the quality of pea sprouts by combined application of nano‐selenium and lentinans
Authors: Lin Yongxi , Zhou Chunran , Li Dong , Wu Yangliu , Dong Qinyong , Jia Yujiao , Yu Huan , Miao Peijuan , Pan Canping 
Published: March 2023

AbstractBACKGROUNDLignification causes a detrimental impact on the quality of edible sprouts. However, the mechanism of inhibition of lignification of edible sprouts by nano‐selenium and lentinans remains unclear.RESULTSTo reveal the mechanism of lignification regulation of sprouts by nano‐selenium and lentinans, this study investigated the changes in antioxidant indicators, phytohormones, polyphenols, and metabolites in the lignin biosynthesis in pea sprouts following sprays of nano‐selenium or/and lentinans twice. There was an overall increase in the aforementioned indices following treatment. In particular, the combined application of 5 mg L−1 nano‐selenium and 20 mg L−1 lentinans was more effective than their individual applications in enhancing peroxidase, catalase, DPPH free‐radical scavenging rate, luteolin, and sinapic acid, as well as inhibiting malondialdehyde generation and lignin accumulation. Combined with the results from correlation analysis, nano‐selenium and lentinans may inhibit lignification by enhancing antioxidant systems, inducing phytohormone‐mediated signaling, and enriching precursor metabolites (caffeyl alcohol, sinapyl alcohol, 4‐coumaryl alcohol). In terms of the results of non‐targeted metabolomics, the combined application of 5 mg L−1 nano‐selenium and 20 mg L−1 lentinans mainly affected biosynthesis of plant secondary metabolites, biosynthesis of phenylpropanoids, phenylpropanoid biosynthesis, arginine and proline metabolism, and linoleic acid metabolism pathways, which supported and complemented results from targeted screenings.CONCLUSIONOverall, the combined sprays of nano‐selenium and lentinans showed synergistic effects in delaying lignification and optimizing the quality of pea sprouts. This study provides a novel and practicable technology for delaying lignification in the cultivation of edible sprouts. © 2023 Society of Chemical Industry.
Treatment and survival of patients with malignant ovarian sex cord‐stromal cell tumours: An analysis of the Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) study group CORSETT database
Authors: Klar Maximilian , Plett Helmut , Harter Philipp , Heitz Florian , Kommoss Stefan , Hartkopf Andreas Daniel , Grube Marcel , Roser Eva , Sehouli Jalid , Braicu Iona , Czogalla Bastian , Burges Alexander , Bossart Michaela , Hasanov Mir Fuad , Link Teresa , Staebler Annette , Mayr Doris , Buderath Paul , Hasenburg Annette 
Published: March 2023

AbstractBackgroundMalignant sex cord‐stromal cell tumours (SCST) account for only 7% of ovarian malignancies. The Arbeitsgemeinschaft fuer Gynaekologische Onkologie (AGO) study group has established a clinicopathological database to provide an overview of the current treatment strategies and survival of SCST patients and to identify research needs.MethodsTwenty centres provided mixed retro‐ and prospective data of patients with tumour specimens and second‐opinion pathology review treated between 2000 and 2014. Descriptive analyses of treatment strategies, Kaplan–Meier curves and cox regression analyses were conducted.ResultsTwo hundred and sixty‐two SCST patients were included. One hundred and ninety‐one Granulosa‐cell tumour (GCT) and 17 Sertoli‐Leydig cell tumour (SLCT) patients were stage I disease (>80%). Forty four GCT (18.7%) and two (8.3%) SLCT patients received adjuvant systemic treatment. After a median observation time of 78.2 months, 46% of all SCST patients experienced disease recurrence, treated predominantly with secondary debulking surgery (> 90%). Advanced FIGO stage, lymph node involvement and intra‐operative capsule rupture were associated with disease recurrence on univariate analysis (all p < 0.05). Median OS time was not reached.DiscussionIn this analysis of SCST patients, adjuvant chemotherapy was unable to prevent disease recurrence. Despite high recurrence rates, overall survival rates were excellent.
Geographic variation in organic carbon storage by seagrass beds
Authors: McHenry Jennifer , Rassweiler Andrew , Hernan Gema , Dubel Alexandra K. , Curtin Carolyn , Barzak Jakob , Varias Nicholas , Lester Sarah E. 
Published: March 2023

AbstractSince seagrasses are efficient sinks for marine organic carbon, there is growing interest in incorporating seagrass protection and restoration into climate mitigation schemes, that is, offering credit for accumulated carbon to offset carbon dioxide emissions. However, patterns and drivers of organic carbon storage by seagrasses are not well resolved, especially at scales relevant to management decisions. Here, we quantified geographic variation in standing stocks of sedimentary organic carbon (Mg Corg ha−1) associated with seagrasses along the northern Florida Gulf Coast using field surveys and sediment cores. We measured plant biomass, organic carbon, and sediment composition in each core. Using a multivariate modeling approach, we evaluated the relative importance of ecological, physical, oceanographic, and seascape drivers, developing the first spatially explicit predictions of seagrass‐associated carbon stocks for this region. Applying model predictions to confirmed seagrass beds and potential recovery areas, we also estimated the carbon storage value of potential seagrass conservation and restoration as the resulting stock enhancement value per hectare of seagrass (Δ Mg Corg ha−1). We found that organic carbon stored by seagrass sediments varied considerably across this region, with stocks significantly increasing with seagrass cover, proximity to oyster reefs, and distance from river outlets, highlighting potential synergies for coordinated management. We also found that current seagrass beds could offer nearly double the carbon storage value of potential recovery areas, emphasizing the importance of conservation as well as restoration. Our results have important implications for management, restoration, and understanding biogeographic patterns of seagrass ecosystem services.
Development and In Vivo Assessment of an Injectable Cross‐Linked Cartilage Acellular Matrix‐PEG Hydrogel Scaffold Derived from Porcine Cartilage for Tissue Engineering
Authors: Ju Hyeon Jin , Ji Yun Bae , Kim Shina , Yun Hee‐Woong , Kim Jae Ho , Min Byoung Hyun , Kim Moon Suk 
Published: March 2023

AbstractThe cartilage acellular matrix (CAM) derived from porcine cartilage, which does not induce significant inflammation and provides an environment conducive for cell growth and differentiation, is a promising biomaterial candidate for scaffold fabrication. However, the CAM has a short period in vivo, and the in vivo maintenance is not controlled. Therefore, this study is aimed at developing an injectable hydrogel scaffold using a CAM. The CAM is cross‐linked with a biocompatible polyethylene glycol (PEG) cross‐linker to replace typically used glutaraldehyde (GA) cross‐linker. The cross‐linking degree of cross‐linked CAM by PEG cross‐linker (Cx‐CAM‐PEG) according to the ratios of the CAM and PEG cross‐linker is confirmed by contact angle and heat capacities measured by differential scanning calorimetry. The injectable Cx‐CAM‐PEG suspension exhibits controllable rheological properties and injectability. Additionally, injectable Cx‐CAM‐PEG suspensions with no free aldehyde group are formed in the in vivo hydrogel scaffold almost simultaneously with injection. In vivo maintenance of Cx‐CAM‐PEG is realized by the cross‐linking ratio. The in vivo formed Cx‐CAM‐PEG hydrogel scaffold exhibits certain host–cell infiltration and negligible inflammation within and near the transplanted Cx‐CAM‐PEG hydrogel scaffold. These results suggest that injectable Cx‐CAM‐PEG suspensions, which are safe and biocompatible in vivo, represent potential candidates for (pre‐)clinical scaffolds.
Long‐term cathodic disbondment tests in three‐layer polyethylene coatings
Authors: de Freitas Denise S. , Brasil Simone L. D. C. , Leoni Gabriel , Motta Gustavo X. da , Leite Eduardo G. B. , Coelho Jorge F. P. 
Published: March 2023

AbstractCathodic protection allied to a polymeric coating is one of the most employed techniques to protect buried steel pipelines against corrosion. Nevertheless, cathodic disbondment, a phenomenon associated with such protection in high‐performance coatings such as (three‐layer polyethylene [3LPE]), still concerns the oil and gas segment regarding pipeline integrity. The present work was part of a Program of Integrity Management and studied in field‐like conditions the influence of cathodic potential, type of soil and coating system on the coating disbondment of buried pipelines for 450 days. The coating systems herein studied simulated the patching between aged (coal tar) and new coatings (3LPE), a standard procedure during damaged pipeline repair. Results pointed out that the combination between aged (coal tar) and new coatings (3LPE) in a pipe segment reduced coating disbondment when compared to the systems where 3LPE was the sole type of coating. Moreover, it was shown that more cathodic potentials (<−1100 mV) and the aggressiveness of the industrial soil herein tested induced disbondment diameters as high as 15.5 mm.
Long‐term atmospheric corrosion of Cr‐free painted aluminum alloys during outdoor worldwide exposures
Authors: Peltier Fabienne , Thierry Dominique 
Published: March 2023

AbstractCr‐free paints applied on different aluminum alloys were exposed for 5 years at different atmospheric weathering sites worldwide. By image analysis, the extent, and the type of corrosion (filiform or blistering) were determined after 1, 2, and 5 years. In that way, it was possible to rank the different systems as a function of their resistance to corrosion. The kinetics of degradation of each system at all sites was also determined. From the results, it is shown that the kinetics of degradation is system dependent. It is also shown that it is the combination of several climatic parameters which contributes to the corrosivity of the site and not only one single parameter such as chloride deposition, relative humidity, and so on.
Nonaqueous magnetization following adiabatic and selective pulses in brain: T1 and cross‐relaxation dynamics
Authors: Reynolds Luke A. , Morris Sarah R. , Vavasour Irene M. , Barlow Laura , Laule Cornelia , MacKay Alex L. , Michal Carl A. 
Published: March 2023

AbstractInversion pulses are commonly employed in MRI for
‐weighted contrast and relaxation measurements. In the brain, it is often assumed that adiabatic pulses saturate the nonaqueous magnetization. We investigated this assumption using solid‐state NMR to monitor the nonaqueous signal directly following adiabatic inversion and compared this with signals following hard and soft inversion pulses. The effects of the different preparations on relaxation dynamics were explored. Inversion recovery experiments were performed on ex vivo bovine and porcine brains using 360‐MHz (8.4 T) and 200‐MHz (4.7 T) NMR spectrometers, respectively, using broadband rectangular, adiabatic, and sinc inversion pulses as well as a long rectangular saturation pulse. Analogous human brain MRI experiments were performed at 3 T using single‐slice echo‐planar imaging. Relaxation data were fitted by mono‐ and biexponential decay models. Further fitting analysis was performed using only two inversion delay times. Adiabatic and sinc inversion left much of the nonaqueous magnetization along
and resulted in biexponential relaxation. Saturation of both aqueous and nonaqueous magnetization components led to effectively monoexponential
relaxation. Typical adiabatic inversion pulses do not, as has been widely assumed, saturate the nonaqueous proton magnetization in white matter. Unequal magnetization states in aqueous and nonaqueous 1H reservoirs prepared by soft and adiabatic pulses result in biexponential
relaxation. Both pools must be prepared in the same magnetization state (e.g., saturated or inverted) in order to observe consistent monoexponential relaxation.
Collagen cross‐linking in oral cancer
Authors: Uzawa Katsuhiro , Kasamatsu Atsushi , Yamauchi Mitsuo 
Published: March 2023

AbstractCarcinogenesis is widely recognized to be caused by qualitative and quantitative genetic changes. These changes include abnormalities in gene structure itself and/or in transcriptional mechanisms involved in gene expression in cancer cells and cancer‐associated cells. Emerging evidence has also revealed that the nature of the extracellular matrix (ECM) in the tumor microenvironment actively regulates cancer cell growth, migration, and metastasis. The most abundant protein in the ECM surrounding cancer cells is fibrillar type I collagen that accumulates and stiffens through formation of specific types of covalent intermolecular cross‐links. Alterations in the physicochemical nature of ECM proteins like fibrillar type I collagen can affect cancer cell behavior. This review provides an overview of collagen cross‐linking and its roles in oral cancer as well as possible clinical applications.
Development and validation of the Scale of Emotional Functioning: Education (SEF:ED)
Authors: Anderson Lezli Suzanne , McCallum R. Steve , Castleman David M. , Fast Michelle 
Published: March 2023

AbstractData collected from 97 educators provide preliminary support for the psychometric integrity of an experimental self‐report instrument designed to operationalize emotional intelligence (EI) specifically for educators, the Scale of Emotional Functioning: Educators, or SEF:ED. Data analyses relied in part on results from an exploratory factor analysis, which provided evidence for a three‐factor solution, and additional correlational analyses (e.g., item‐scale correlations). Reliability estimates (i.e., split‐half reliability correlations) for the SEF:ED Emotional Awareness, Emotional Management, and Interpersonal Relations subscales are .86, .80, and .71, respectively. Correlation coefficients (i.e., Pearson r) between the SEF:ED composites and the Profile of Emotional Competence composites (PEC) range from .35 to .72, providing evidence for concurrent validity of the SEF:ED. Finally, correlation coefficients between SEF:ED and the Maslach Burnout Inventory for Educators (MBI‐ES) range from −.21 to .59 and provide limited evidence of its ability to predict an important work site characteristic, that is, burnout. Once the SEF:ED was completed, descriptive statistics were obtained for EI and burnout and show relatively similar means/standard deviations across various demographics (e.g., gender, educator degree, years in service, and classroom setting—general vs. special education). Limitations of the study and implications for application of the SEF:ED are discussed.