bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDI KOMPARATIF INVITRO AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, FRAKSI ETIL ASETAT DAN ISOLAT AKTIF KULIT DELIMA (PUNICA GRANATUM L.)
Authors: Wahyuni Sri , Mahmuda Iin Novita Nurhidayati , Maryati  , Perdana Aditya Putra , Azizah Maharotullaili Nur 
Published: April 2023

ABSTRACT
Pomegranate (Punica granatum L) is widely used for health. Pomegranate peel is part of the pomegranate fruit which is often discarded and has not been widely used. Pomegranate peel is thought to contain antioxidants. One of the examinations for antioxidants is the 1,1 dipheyl-2-picrylhydrazyl (DPPH) method, by calculating the IC50 value, where the smaller the IC50 value means that the stronger of antioxidant potential. The purpose of this study was to compare the antioxidant activity of the ethanol extract, ethyl acetate fraction, and the active isolate from pomegranate peel. The antioxidant potency was tested using the DPPH, using the UV-Vis spectrophotometer, at 515 nm wavelength. Isolation of isolates was carried out by column chromatography shepadex and TLC with toluene as mobile phase; ethyl acetate : formic acid : methanol, with a ratio of 3:3:0.8:0.2. The purity of the isolate was detected by HPLC, with water-methanol as the mobile phase. The research results showed that 96% ethanol extract, ethyl acetate fraction and active isolate from pomegranate peel have potential as antioxidants with IC50 4.52 ± 0.00, 2.71 ± 0.01, and 0.979 x 10-5 ± 0.00 µg/mL, respectively, the positive control was vitamin C, had an IC50 3.66 ± 0.02 µg/mL. The conclusion of this study is that pomegranate peel isolate has the strongest antioxidant potential, compared to 96% ethanol extract and the ethyl acetate fraction of pomegranate peel, and even vitamin C.
ABSTRAK
Delima (Punica granatum L) banyak dimanfaatkan untuk kesehatan. Kulit delima merupakan bagian dari delima yang sering kali dibuang dan belum banyak dimanfaatkan. Kulit delima diduga memiliki kandungan antioksidan. Salah satu pemeriksaan antioksidan adalah dengan metode 1,1 dipheyl-2-picrylhydrazyl (DPPH), dengan menghitung nilai IC50, dimana semakin kecil nilai IC50 dapat diartikan bahwa semakin kuat potensi antioksidannya. Tujuan dari penelitian ini adalah untuk membandingkan aktivitas antioksidan dari ektrak etanol, fraksi etil asetat, dan isolat aktif kulit delima. Potensi antioksidan diuji dengan metode DPPH, dengan menggunakan spektrofotometer UV-Vis, pada panjang gelombang 515 nm. Isolasi isolat dilakukan dengan kromatografi kolom shepadex dan KLT dengan fase gerak toluene: etil asetat: asam format: metanol, dengan perbandingan 3:3:0.8:0.2. Kemurnian isolat di deteksi dengan HPLC, dengan fase gerak air-metanol. Hasil peneiltian menunjukan bahwa ekstrak etanol 96%, fraksi etil asetat dan isolat aktif dari kulit delima memiliki potensi sebagai antioksidan, dengan nilai IC50 masing-masing sebesar 4,52 ± 0,00; 2,71 ± 0,01; dan 0,979 x 10-5 ± 0,00 µg/ mL, sebagai kontrol positif vitamin C memiliki nilai IC50 3,66 ± 0,02 µg/ mL. Kesimpulan penelitian ini adalah bahwa isolat kulit delima memiliki potensi antioksidan terkuat, dibandingkan ekstrak etanol 96% dan fraksi etil asetat kulit delima, bahkan juga vitamin C.
HUMAN HERPESVIRUS-6 MENINGOENCEPHALITIS AND PULMONARY TUBERCULOSIS IN HIV PATIENT: A CASE REPORT
Authors: Prabaningtyas Hanindia Riani , Putra Stefanus Erdana , Hafizhan Muhammad , Mirawati Diah Kurnia , Budianto Pepi 
Published: April 2023

ABSTRACT
Human herpesvirus 6 (HHV-6), the causative agent of exanthema subitum in childhood, could also induce meningoencephalitis in immunocompromised individuals. We reported a case of 32-years-old woman with complaints of worsen headache, one week before admission. She also had intermittent fever and weakness in her left limb. She was admitted to a local hospital, suspected with tuberculous meningitis and pulmonary tuberculosis, and treated with anti-tuberculosis drugs, antibiotics for bacterial meningitis and steroids. She did not show any improvement, and then referred to X Surakarta General Hospital. On physical examination, we found GCS of E3V3M5, crackles and wheezing throughout the lung, neck stiffness, left hemiparesis, and clonus of the left lower leg. Laboratory results showed increasing leukocytes, reactive anti-HIV, and positive PCR for HHV-6 in the cerebrospinal fluid. On the CT scan, there were multiple hypodense lesions in the pons and right internal capsule, and communicant hydrocephalus. She was treated with highly active anti-retroviral therapy (HAART), Valganciclovir 900 mg b.i.d., steroid, anti-tuberculosis drugs and symptomatic treatment. After three weeks of admission, she began to show improvement, level of consciousness increased, and allowed went home.
ABSTRAK
Human herpesvirus-6 (HHV-6), agen penyebab eksantema subitum pada masa kanak-kanak, juga dapat menyebabkan meningoensefalitis pada individu dengan gangguan sistem imun. Kami melaporkan sebuah kasus, seorang wanita berusia 32 tahun dengan keluhan nyeri kepala yang semakin memberat sejak satu minggu sebelum masuk rumah sakit. Selain itu, pasien juga mengeluh demam intermiten dan kelemahan pada tungkai kiri. Pasien dirawat di rumah sakit lokal dengan diagnosis suspek meningitis tuberkulosis dan tuberkulosis paru dan ditatalaksana dengan obat anti tuberkulosis, antibiotik untuk meningitis bakteri dan steroid. Karena tidak ada perbaikan, pasien dirujuk ke RS X Surakarta. Pada pemeriksaan fisik ditemukan GCS E3V3M5, ronki dan mengi di seluruh lapang paru, kaku kuduk, hemiparesis kiri, dan klonus tungkai bawah kiri. Hasil laboratorium menunjukkan peningkatan leukosit, anti-HIV reaktif, dan PCR HHV-6 positif pada cairan serebrospinal. Pada CT-scan ditemukan lesi hipodens multipel pada pons dan capsula interna kanan serta hidrosefalus komunikan. Pasien ditatalaksana dengan highly active anti-retroviral therapy (HAART), Valgansiklovir 900mg/12 jam, steroid, obat anti tuberkulosis dan pengobatan simtomatik. Setelah perawatan selama tiga minggu, pasien mulai menunjukkan perbaikan, tingkat kesadaran meningkat, dan diperbolehkan pulang.
DOES FINANCIAL INCLUSION AFFECT PROFITABILITY OF COMMERCIAL BANKS?
Authors: Nguyen Thuy Duong , Nguyen Ngoc Tram , Nguyen Duc Huy , Huynh Anh Thu , Nguyen Thu Ha 
Published: April 2023

Purpose: The objective of this study is to investigate the impact of financial inclusion on commercial banks profitability in 60 countries between 2017 and 2021.
Design/Methodology/Approach: The study used 300 observations from countries with developed and undeveloped banking systems. The paper applies estimation methods including Pooled OLS, FEM, REM and GLS related to panel data as well as multicollinearity, heteroscedasticity tests for model selection.
Research findings: Similar to previous papers, this research proved that most financial inclusion indicators have positive correlation with commercial banks profitability. In addition, this research suggested 3 new variables and pointed out: “Institutions of commercial banks”; “Outstanding-loans with commercial banks” positively impact banks profitability whereas “Outstanding-deposits with commercial banks” has negative influence on banks profitability.
Theoretical contribution/Originality: The majority of previous papers have explored the effect of financial inclusion at the national level, for example, the relationship between financial inclusion and economic growth. Meanwhile, this paper investigated the impact of financial inclusion on commercial bank profitability, an issue concerned recently.
Policy implication: This study can assist countries achieve a higher level of financial inclusion to raise commercial banks profitability, thereby boosting economic growth.
Comparative Analysis of Implementation of Murabahah Bil Wakalah Contracts and Musyarakah Mutanaqisah Contracts for Sharia Financing Products
Authors: Intansari Anggita Isty , Fatimah  
Published: April 2023

A home is a basic human need that plays an important role in the continuation of human life. The problem of housing and settlement has existed and will continue to exist in response to population growth, demographics and socio-economic needs. The high demand for housing and population growth provide opportunities for Islamic financial institutions to provide products that help people purchase housing.
The purpose of this study is to determine the application of the Murabaha Contract and the Musharaka Mutanaqisah Contract and find a comparison of her two contracts in Islamic KPR funding. Knowing the mechanism and type of research represents field research. This research was conducted using qualitative methods with a descriptive approach.
As a result of the research and analysis, it was found that the application of the Murabaha Bil Wakala Convention takes precedence over the Musharaka Mutanaqishah Convention. A comparison of the two loan agreements can then be viewed in terms of similarities and differences between the two agreements.
Formulasi Sediaan Nanoemulgel Ekstrak Buah Lada Hitam (Piper ningrum L.) dengan Variasi Konsentrasi Tween 80 dan PEG 400
Authors: Andini Septia , Yulianita Yulianita , Febriani E Nurul Kholisoh 
Published: April 2023

Buah lada hitam memiliki komponen utama yaitu senyawa piperin yang berkhasiat sebagai antiinflamasi. Pemakaian secara topikal dengan penghantaran obat melalui TDDS (Transdermal drug delivery system) diharapkan dapat meningkatkan penetrasi obat sehingga lebih efektif. Nanoemulgel merupakan sediaan nanoemulsi dengan ukuran droplet kisaran 50-1000 nm dengan penambahan basis gel. Nanoemulgel dipilih karena sistem penghantaran obat berpenetrsi kedalam kulit sehingga dapat meningkatkan bioavailabilitas suatu zat aktif. Penelitian ini bertujuan untuk membuat sediaan Nanoemulgel dengan variasi konsentrasi surfaktan Tween 80 dan kosurfaktan PEG 400. Sebanyak tiga formula dibuat dengan variasi konsentrasi surfaktan Tween 80 dan kosurfaktan PEG 400 yaitu F1 (30:30); F2 (35:25); dan F3 (40:20). Ekstraksi buah lada hitam dengan metode sokletasi dengan pelarut etanol 96%. Tahap pembuatan sediaan Nanoemulgel dibuat dalam 3 tahap yaitu pembuatan nanoemulsi, pembuatan basis gel dan pencampuran nanoemulsi ke dalam basis gel. Hasil penelitian menunjukkan Formula 3 merupakan formula terbaik dan stabil dilihat dari hasil pengujian ukuran partikel (59,37) nm, polidispersitas indeks (0,25), zeta potensial (-28,9) mV, dan pH sediaan (5,60±0,01).
Capacidad estabilizadora del transverso abdominal en halterófilos de la federación deportiva del Azuay
Authors: Rodriguez Anthony , Vivar Kevin 
Published: April 2023

Objetivos: Determinar la capacidad estabilizadora del Transverso abdominal a través del Test de estabilidad central de Sahrmann en deportistas de halterofilia de la Federación Deportiva del Azuay.
Métodos: Estudio descriptivo, transversal, realizado en deportistas de la FDA. Para la recolección de datos se utilizó un formulario de registro y para la evaluación el Test de Estabilidad Central de Sahrmann junto con el dispositivo Chattanooga Stabilizer Pressure Biofeedback. La tabulación y análisis de los datos requirió de los programas GNU PSPP v1.6.2 y Microsoft Excel 2016. La información se almacenó en una base de datos y los resultados fueron expresados en tablas.
Resultados: Más de la mitad de la población estudiada (66.6%) presenta una menor capacidad estabilizadora alcanzando los niveles 1 y 2 en su mayoría mediante la ejecución del test de estabilidad central de Sahrmann.
Conclusiones: Nuestros resultados permitieron identificar que la capacidad de activación del TrA es insuficiente, con una estabilidad reducida en un 66,7% de los atletas de la Federación Deportiva del Azuay, al no alcanzar un nivel superior a 2 en el test de estabilidad de Sahrmann, lo que sugiere un alto riesgo de lesión.
Skin biopsy guidelines: tips and advice from veterinary pathologists to practitioners
Authors: Craft William F. , Marsella Rosanna , Rodrigues-Hoffmann Aline 
Published: April 2023

Abstract
Skin diseases are one of the most common problems seen in veterinary practices around the world. Many patients are presented with severe and/or chronic lesions, often refractory to treatment, and collection of skin biopsies is often beneficial to obtain or confirm a diagnosis and to help guide a management plan for patients. To obtain valuable information from skin biopsies, practitioners should follow recommended guidelines based on drug withdrawal and washout period, identification, and proper collection of skin lesions, which should be at different stages of progression, as well as include a thorough clinical history and differential list. These different steps taken prior to the submission of samples will often increase the chances of a more accurate diagnosis. Practitioners should also understand it may not always be possible for pathologists to provide a definitive diagnosis, but the information provided with skin biopsies can often be used to guide an appropriate treatment plan. This review will present general guidelines and suggestions to help obtain the most diagnostic skin samples for histopathological evaluation.
Types of Operational Mathematical Procedures in Dynamics Descriptions. A Short Note
Authors: Gavriluț Gabriel , Saviuc Alexandra , Rusu Cristina-Marcela , Petrescu Tudor-Cristian , Oprea Iuliana 
Published: April 2023

Abstract
Assuming that the dynamics of complex systems can be described on continuous and non-differentiable curves, a multifractal mathematical procedure was proposed to analyze the dynamics of complex systems. Thus, using the Schrodinger monofractal model and the hydrodynamic multifractal model, in the case of the dynamics of systems described by Peano-type fractal curves, fractal theories of movement can be developed.
A Comparison of Sedimentation Method and Active Sampler Analysis of Microbiological Indoor Air Quality - Case Study
Authors: Przystaś Wioletta , Zabłocka-Godlewska Ewa , Melaniuk-Wolny Edyta 
Published: April 2023

Abstract
The indoor air quality is of great importance for the health of people. Appropriate selection of methods, parameters and conditions for the analysis makes it possible to obtain the results that reliably reflect the actual state of affairs. The aim of this study was to compare the results of microbiological air analysis in selected rooms of the Biotechnology Center obtained using the sedimentation method and the impaction method. During the research, the SMA (for total bacteria number) and Sabouraud media (for total fungi number) were exposed to different times in sedimentation analysis and to different air volumes in the impaction method. In the case of the sedimentation method, significant differences were found in the total number of bacteria and fungi in 3 out of 7 rooms depending on the time of exposure. In the case of the impaction method, it was 4 out of 7 rooms for bacteria and 2 out of 7 for fungi, depending on the analysed volume of air. The comparison of the methods showed that 4 out of 6 rooms had higher number of microorganisms when impactor was used.
Model of Deep Information Environmental Factors on the Development of ICE and Snow Sports
Authors: Zhu Yongguo , Li Qiao , Ying Zhanpeng , Tian Shuxin 
Published: April 2023

Abstract
Driven by national policies and international competitions, China’s winter sports and industry development will enter a new course. How to release the enormous potential skiing demand in China is significant to drive 300 million people to participate in winter sports and promote the development of China’s ice and snow industry, and defining the restrictive factors is a necessary prerequisite to realise the effective transformation of potential demand to actual growth power. Based on the in-depth information, this paper further analyses the influence of environmental factors on the development of winter sports. The research shows that the number of skiers about 20 times is the highest, up to 75.5 %, followed by the number of skiers about five times, up to 67.4 %. Then about ten times accounted for 48.6 %, and finally, about 15 times accounted for 37.6 %. This frequency can fully satisfy skiing enthusiasts to enjoy leisure activities, experience modern life fashion, use skiing to increase social opportunities, delight body and mind, and improve health. Based on the in-depth information, this paper reveals the shortcomings and existing environmental factors of China’s winter sports development. It provides a reference for the rational utilisation and development of ice and snow resources and the scientific and practical development of China’s winter sports.
Assessment of the efficiency of use of EPS by business
Authors: Volvach Olena 
Published: April 2023

Abstract
As the world became more digitalized thanks to the Internet, it led to the creation of Electronic Payment Systems that are now used to seeing all over the world, but there is a need for estimation the return on development and implementation of EPSs. The research goal is to develop an approach based on optimization modeling for the assessment of the efficiency of implementation and the use of electronic payment systems by Ukrainian and international businesses for their day-by-day operations. The article also analyzed different classifications of EPS and determined several types of methodology for the evaluation of the effectiveness of the EPS (absolute and relative to business results and costs). Using the optimization model and system analysis, the authors proposed the algorithm for the estimation of profit from EPS implementation (both separate EPS or portfolio of EPSs) and make an experiment for one of the EPS for the period of 2023-2026. The optimization model includes revenue from EPS, as well as salary, rent, and infrastructure costs, which helps to improve the results of EPS implementation by adapting of transaction’s tariff. Authors also described the process of solving optimization task for determining effective tariff per 1 transaction, taking into account marketing information.
Vittorio Benussi, the Gustav Mahler of Psychology*
Authors: Antonelli Mauro 
Published: April 2023

SummaryThe paper celebrates the person and work of Vittorio Benussi, a forgotten genius of psychology. In particular, it addresses the two most important scientific projects that Benussi developed during his time in Graz and Padua, respectively: the psychology of perception and the psychology of emotions and the unconscious. It highlights the originality and topicality of Benussi’s work and emphasizes its proximity to the latest trends in these research fields.
The Experimental Phenomenology of Perception. A Collective Reflection on the Present and Future of this Approach
Authors: Bianchi Ivana , Burro Roberto 
Published: April 2023

Summary
The paper presents the result of a collective reflection inspired by the individual suggestions of 30 researchers working in different research areas. They are all familiar with the Experimental Phenomenology of Perception, and are aware of the importance that this approach might represent nowadays in their specific research field. The picture that emerges from this ‘mosaic’ stimulates us to consider the potential future developments of this approach if we accept that we need to push its borders beyond the traditional aims of the study of perception (as masterfully developed by the historic Italian Maestri of this approach). If we take this broader view, the Experimental Phenomenology of Perception can extend its perimeters from an analysis of strictly perceptual aspects to an analysis of cognitive and metacognitive aspects (such as aesthetic evaluations, the perception of risk, the experience of certainty/uncertainty in a reasoning process, the perception of proximity to/distance from the solution to a problem and meaning-making in language). The cognitive and metacognitive aspects referred to are grounded in and modelled on the perceiver’s experience of a given situation.
Gestalt road to Necker cube perception
Authors: Guberman Shelia 
Published: April 2023

Abstract
The study of cases of illusory or unstable perception of some visual stimuli allows exploration of the psychology of perception of the surrounding world. The wired construction known as “Necker cube” is one such stimulus: it can be perceived as a cube whose front face is seen higher than the back face or vice versa. The switch can occur intentionally or spontaneously. The investigations were focused on switching parameters, relation of the switching to eye position, pre-history, and environment. Here we define that the kernel of the problem is recognizing the 2D drawing as a 3D Necker cube. To this end, we have expanded Gestalt's psychology methods that allow us to recognize 2D figures in drawings for recognizing 3D figure in a flat drawing (including the Necker cube). The presented algorithm for recognizing the cube based on the imitation principle allowed the development of the model of switching between two possible perceptions of the Necker cube. The paper shows that the predictions are in conformity with previously available experimental data. The results confirm the imitation principle of perception, and suggest expanding our research on perception to a wider class of 3D figures, opening a window into the internal processes of perception.
Inflammation, Gestational Hypertension, and Preeclampsia – a Dangerous Association
Authors: Corduneanu Alina-Georgiana , Păvăleanu Ioana , Capilna Mihai Emil 
Published: April 2023

Abstract
Gestational hypertension and preeclampsia complicate 2–8% of pregnancies, with a great impact on the fetuses, as well as on maternal well-being. Preeclampsia is considered a major cardiovascular emergency due to its potential to evolve to severe eclampsia, a devastating life-threatening condition. Worldwide, preeclampsia is considered to be one of the major factors that lead to maternal and fetal death. On average, hypertensive disorders are responsible for approximately 16% of maternal deaths, and every year, preeclampsia is estimated to cause more than 500,000 deaths of the fetus and 70,000 maternal deaths all over the world. While different studies published so far have not succeeded in identifying the exact mechanisms that cause preeclampsia, ischemic vascular phenomena, immunological disorders, and inflammation have been reported as important factors involved in its pathogenesis. The current review aims to provide updated, relevant literature data regarding the potential link between elevated inflammatory status and preeclampsia, at the same time underlining the role of emerging imaging techniques for the early detection of preeclamptic risk.