bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERAMALAN PERSEDIAAN VOUCHER INTERNET DENGAN METODE SINGLE SINGLE EXPONENTIAL SMOOTHING
Authors: Lubis Mustapa Husein , Tanjung Akhir Abadi , Martina Desy 
Published: May 2023

Abstract: Forecasting is predicting something that will happen using past data. Research conducted on the Preza Data package on internet voucher inventory. To make it easier for stores to predict internet inventory, a forecasting technique is used which by using this technique the company can predict the amount of internet voucher inventory for the future. The internal voucher inventory forecasting system uses the Single Exponential Smoothing method. The exponential smoothing method is used in order to see the amount of internet voucher inventory for the future by using the latest data to reduce past data irregularities. The data used to calculate forecasting uses internet voucher inventory data in 2019. From the test results it was found that this forecasting ability was very good because it had a MAPE value of less than 20%. At the sample test stage, it was found that the forecast for the number of internet voucher supplies in March 2021 was 1479 with an error rate of 3.89%. This forecasting has actually been used because the MAPE value is less than 20%. Keywords: Forecasting; Internet Voucher Inventory; Single Exponential Smoothing. Abstrak: Peramalan adalah memperkirakan sesuatu yang akan terjadi dengan menggunakan data-data masa lalu.. Penelitian di lakukan pada Preza paket Data tentang jumlah persediaan voucher internet. Untuk mempermudah toko dalam memprediksi persediaan voucher internet maka digunakanlah suatu teknik peramalan yang mana dengan menggunakan teknik ini perusahaan dapat memprediksi jumlah persediaan voucher internet untuk masa yang akan datang. Sistem peramalan persediaan voucher internemenggunakan metode Single Exponential Smoothing. Metode exponential smoothing digunakan agar bisa mengetahui jumlah persediaan voucher untuk masa yang akan datang dengan menggunakan data terbaru untuk mengurangi ketidakteraturan data masa lampau. Data yang digunakan untuk menghitung peramalan menggunakan data persediaan voucher internet tahun 2019. Dari hasil pengujian didapat bahwa kemampuan peramalan ini sangat baik karena memiliki nilai MAPE kurang dari 20%. Pada tahap uji sample didapat bahwa peramalan jumlah persediaan voucher internet bulan Maret 2021 berjumlah 1479 dengan tingkat error adalah 3,89 %. Peramalan ini sudah aktual digunakan karna nilai MAPE kurang dari 20% Kata kunci: Peramalan; Persediaan Voucher Internet; Single Exponential Smoothing.
PENERAPAN METODE AHP PADA PENENTUAN PRIORITAS PROYEK AIR BERSIH DI KABUPATEN ASAHAN
Authors: Aulia Dewi , Siddik Mohd , Latiffani Chitra 
Published: May 2023

Abstract: Asahan Regency is one of the 33 regencies/cities in North Sumatra Province. Coastal areas are still lagging behind because they are far from urban areas so that the government pays little attention to it, especially regarding clean water. Clean water in the area can be said to be unfit for use. So that people find it difficult to get clean water for drinking, washing and bathing. These problems can be solved by programs to improve clean water infrastructure and facilities, such as drilling wells and allocating river water, so that they can provide optimal services for clean water, which has a very strong relationship with the economic growth of a region and the socio-cultural life of the community. Determining the priority scale for clean water must look at various criteria so as to produce accurate and precise results. Space so as to allow the results to be less accurate and not on target as well as errors in determining which clean water should be prioritized, so that a decision support system is needed that can assist in determining which villages have the right to take precedence in the priority of clean water projects. The method used for the decision support system is AHP method. Keywords: Priority Determination of Clean Water Projects; AHP Method. Abstrak: Kabupaten Asahan merupakan salah satu kabupaten dari 33 kabupaten/kota yang ada di Provinsi Sumatera Utara. Di wilayah Pesisir masih tertinggal karena letaknya yang jauh dari perkotaan sehingga kurang diperhatikan oleh pemerintah, terutama mengenai air bersih. Air bersih di wilayah tersebut bisa di bilang tidak layak untuk digunakan. Sehingga masyarakat kesulitan untuk mendapatkan air bersih baik itu untuk diminum, menyuci dan mandi. Dengan mempertimbangkan hal tersebut maka perlu diterapkan penentuan skala prioritas yang dapat digunakan sebagai suatu acuan dalam penyusunan program proyek untuk tahun anggaran berikutnya. Penentuan skala prioritas air bersih tersebut harus melihat dari berbagai kriteria sehingga menghasilkan hasil yang akurat dan tepat, selama ini penetuan masih berdasarkan musrembang dari pihak Dinas Pekerjaan Umum dan Penataan Ruang sehingga memungkinkan hasil kurang akurat dan kurang tepat sasaran serta terjadinya kesalahan dalam penentuan air bersih yang harus diutamakan, sehingga diperlukan suatu sistem pendukung keputusan yang dapat membantu dalam menentukan desa mana yang berhak didahulukan dalam prioritas proyek air bersih Metode yang digunakan untuk sistem pendukung keputusan adalah Metode AHP. Kata Kunci : Penentuan Prioritas Proyek Air Bersih; Metode AHP.
PENERAPAN METODE NAÏVE BAYES DALAM PENENTUAN GIZI PADA IBU HAMIL DI KELURAHAN BUNGA TANJUNG
Authors: Rahmadani Depy , Handoko Wiwin , Sriutami Fuji , Br.Siagian Khairini Utami 
Published: May 2023

Abstract: Nutrition is one of the determinants of the quality of human resources. Food given to pregnant women must contain nutrients as needed, so as to support optimal growth and can prevent malnutrition in pregnant women and also help prevent the occurrence of diseases that can interfere with pregnant women. Determination of good nutrition and malnutrition in pregnant women in the sub-district of Datuk Bandar Timur District, Tanjung Balai City must meet the criteria are age, graphida, body weight, lila, hemoglobin and decision. For pregnant women with normal body weight <25 kg, increased energy intake is needed only after pregnancy to increase the metabolic needs of the mother and the energy needs of the growing fetus. The purpose of this study was to determine good nutrition and malnutrition using the Naïve Bayes method which resulted in a decision on good nutrition and malnutrition in pregnant women. Naive Bayes is a simple probabilistic classifier that calculates a set of probabilities by summing the frequencies and combinations of values from a given dataset. Naïve Bayes produces a Precision value for the positive class of 85%, for the negative class of 86%, the recall value for the positive class is 92%, for the negative class is 75%, the f1-score value for the positive class is 88%, for the negative class is 80%, and 85% for accuracy. Keywords: Machine Learning, Naïve Bayes; Nutritional Status. Abstract: Gizi merupakan salah satu penentu kualitas sumber daya manusia. Makanan yang diberikan pada ibu hamil harus mengandung zat gizi sesuai kebutuhan, sehingga menunjang pertumbuhan yang optimal dan dapat mencegah kurang gizi pada ibu hamil dan juga membantu mencegah timbulnya penyakit-penyakit yang dapat mengganggu ibu hamil. Penentuan gizi baik dan gizi buruk pada ibu hamil di Kelurahan Bunga Tanjung Kecamatan Datuk Bandar Timur, Kota Tanjung Balai harus memenuhi kriteria yaitu umur, grapida, berat badan, lila, hemoglobin dan keputusan. Untuk ibu hamil dengan berat badan normal <25 kg, peningkatan asupan energi diperlukan hanya setelah kehamilan untuk meningkatkan kebutuhan metabolisme yang dibutuhkan ibu dan kebutuhan energi janin yang sedang tumbuh. Tujuan penelitian ini untuk penentuan gizi baik dan gizi buruk dengan menggunakan metode naïve bayes yang menghasilkan sebuah keputusan gizi baik dan gizi buruk pada ibu hamil. Naive Bayes merupakan sebuah pengklasifikasian probabilistik sederhana yang menghitung sekumpulan probabilitas dengan menjumlahkan frekuensi dan kombinasi nilai dari dataset yang diberikan. Naïve Bayes menghasilkan nilai Precision untuk kelas positif 85%, untuk kelas negatif 86%, nilai recall untuk kelas positif 92%, untuk kelas negatif 75%, nilai f1-score untuk kelas positif 88%, untuk kelas negatif sebesar 80%, dan nilai akurasi 85%. Kata Kunci: Machine Learning; Naïve Bayes; Status Gizi.
THE LENGTH AND THE STRUCTURE OF THE COPY TEXT OF SHEVCHENKO’S POEM “THE GREAT VAULT”
Authors: Boron Oleksandr 
Published: May 2023

stands in Subotiv village...” to the text of Shevchenko’s poem “Th e Great Vault”. Stanislav Rosovetskyi provided a detailed criticism of this decision in his time, and his counterarguments are consistently considered in the paper. Most of them are refuted or questioned, false statements and inaccurate information are corrected.
As a result, the following vision of the history of poem’s creation and circulation has been substantiated. In the early October 1845 in Myrhorod, Shevchenko completed the poem “The Great Vault”, the text of which still might not have had an epigraph and epilogue. Probably, a later copy that belonged to Ivan Lazarevskyi indirectly comes from this autograph. While in Maryinske the poet added an epigraph and on October 21 added the epilogue “There stands in Subotiv village...”, marking the date and place of creation. At that time, according to Olexandr Afanasiev-Chuzhbynskyi, whom the poet met in Lubny on October 25 and stayed with in Iskivtsi on October 25—27, the mystery play had no name. After returning to Kyiv, in approximately April — June 1846 Shevchenko rewrote “The Great Vault” along with other works from an unknown autograph to the manuscript collection “Three Years” in such a way that the epilogue of the poem could be mistaken for a separate work, as it was misunderstood by Vasyl Bilozerskyi who copied the mystery without the final fragment. Obviously, the same mistake was made by other copyists, who started the tradition of “Th e Great Vault” without the epilogue. When Shevchenko received an imperfect copy of I. Lazarevskyi, he had no choice but to edit only what it contained.
Apparently, he did not object to the fact that in the copy of Lev Zhemchuzhnykov the final fragment was called “Subotiv”. It is suggested to increase the distance between the end of the third part of the poem and the beginning of the epilogue in the next academic edition, as well as to reproduce all the graphics of the poetic texts in editions closer to the autographs.
Evaluation of integrated pest management based techniques against insect pests associated with tomato at Uthal Balochistan, Pakistan
Authors: Magsi Zahida , Memon Shafique Ahmed , Ali Arif , Baloch Dost Muhammad 
Published: May 2023

Insect pests are soft-bodied and tiny creatures with plant sap sucking habits that devastate various agricultural crops, fruit trees, ornamental plants and several vegetables. To control these insect pests four IPM techniques were used in tomato field with an aim to minimize the use of synthetic pesticides. Five colours of sticky traps (yellow, green, blue, black and red), Five different colours light trap (red, blue, yellow, green and white), three botanical insecticides (bitter Apple, tobacco, and neem seed extract) with 30% concentration and three synthetic insecticides (emmamectin benzoate, profenophos and bifenthrin) along with water as a control were used. A maximum pest population of jassid, whitefly, thrips, leaf minor, psyllid and flea beetle was observed on yellow sticky traps, while a minimum pest population of jassid, whitefly, thrips, leaf minor, psyllid and flea beetle was noticed on black and red sticky trap. However a highest pest population of fruit borer, psyllid, blister beetle, asparagus beetle, white fly, flea beetle and fruit fly was observed on white and yellow light colour as compared with others lights. However, no statistically significant differences were observed in jassid and earwings pest population on all given colure of lights. The minimum decreased population of white fly, Jassid, thrips and aphids was observed on all three inorganic pesticides as compared with all three organic pesticides and control group. Similarly pest populations reductions of white white fly, Jassid, thrips and aphid was found on all three organic pesticides neem seed, tobacco and bitter apple as compared to control group. We concluded that use of IPM techniques may be encouraged to suppress the insect pest population of tomato crop which could be ultimately positive for the environment
Assessment of effect of fluoride pollution on germination rate, vigor index and fluoride contents in some selected varieties of wheat crop (Triticum aestivum L.)
Authors: Dad Khaliq , Zhao Fenliang , Zhao Fenliang , Iftikhar Sumiyya , Khan Manal Nadeem , Ali Fatima , Fatima Iqra , Nawab Momal , Khan Rania Mazhar , Majid Khansa , Bilal Khola , Nawaz Muhammad 
Published: May 2023

Wheat being staple food and a source of economy in Pakistan is cultivated on large scale every year. Due to increasing environmental pollution, this crop is being affected directly or indirectly. Fluoride is one of the most toxic pollutants among rest of the environmental pollutants. A pot experiment was conducted to examine the impacts of fluoride toxicity on the seed germination, seedlings growth and F ion accumulation in locally cultivated varieties of wheat crop. In this regards, 5 wheat varieties (Akbar 2019, Anaj 2017, Ujala 2016, Galaxy 2016 and AARI 2011) were sown in green house at Bahauddin Zakaryia University (BZU), Multan, Pakistan by applying five (3 mM, 5mM, 7mM, 9mM and 11mM) treatments of NaF and control (0mM). Germination percentage, vigor index and F accumulation in roots and shoots were considered as parameters of research. Anaj 2017 and Akbar 2019 were exhibiting the highest germination percentage at 3mM (87% and 75%) while at 11 mM only Akbar 2019 showed 13% of germination rate as compared to that of control and rest of varieties. Vigor index was also found maximum 193.3 at 11mM of NaF in Anaj 2017. The fluoride contents were recorded higher in roots as compared to that of shoots in all varieties of wheat i.e. at 11 mM, 1 ug of F was found in AARI 2011 which was observed higher as compared to that of control as well as rest of varieties.
Acute cannabidiol treatment enhances social interaction in adult male mice
Authors: Ferreira Livia F. , Pathapati Nikhita , Schultz Stephen T. , Nunn Mary C. , Pierce Bethany L. , Sanchez Yatzil R. , Murrell Meredith D. , Ginsburg Brett C. , Onaivi Emmanuel S. , Gould Georgianna G. 
Published: May 2023

Cannabidiol (CBD) is a non-intoxicating phytochemical from Cannabis sativa that is increasingly used to manage pain. The potential for CBD to ameliorate dimensional behavior symptoms occurring in multiple psychiatric disorders was suggested, including social interaction impairments. To test this hypothesis, adult male BTBRT+Itpr3tf/J (BTBR) mice, a model of idiopathic autism exhibiting social preference deficits and restrictive repetitive behaviors, were acutely treated with vehicle or 0.1, 1, or 10 mg/kg CBD. Social interaction preference was assessed 50 min after treatment, followed by social novelty preference at 60 min, marble burying at 75 min and social dominance at 120 min. CBD (10 mg/kg) enhanced BTBR social interaction but not social novelty preference, marble burying or dominance, with serum levels = 29 ± 11 ng/mg at 3 h post-injection. Next, acute 10 mg/kg CBD was compared to vehicle treatment in male serotonin transporter (SERT) knock-out mice, since SERT deficiency is an autism risk factor, and in their wildtype background strain controls C57BL/6J mice. CBD treatment generally enhanced social interaction preference and attenuated social novelty preference, yet neither marble burying nor dominance was affected. These findings show acute treatment with as little as 10 mg/kg purified CBD can enhance social interaction preference in male mice that are otherwise socially deficient.
Down-regulation of β-lactam antibiotics resistance and biofilm formation by Staphylococcus epidermidis is associated with isookanin
Authors: Ren Qiang , Luo Wanhe , Chi Haoming , Zhang Lili , Chen Wei 
Published: May 2023

IntroductionBiofilm formation is the major pathogenicity of Staphylococcus epidermidis (S. epidermidis), which enhances bacterial resistance to antibiotics. Isookanin has potential inhibitory activity on biofilm.MethodThe inhibiting mechanisms of isookanin against biofilm formation through surface hydrophobicity assay, exopolysaccharides, eDNA, gene expression analysis, microscopic visualization, and molecular docking were explored. Additionally, the combination of isookanin and β-lactam antibiotics were evaluated by the broth micro-checkerboard assay.ResultsThe results showed that isookanin could decrease the biofilm formation of S. epidermidis by ≥85% at 250 μg/mL. The exopolysaccharides, eDNA and surface hydrophobicity were reduced after treatment with isookanin. Microscopic visualization analysis showed that there were fewer bacteria on the surface of the microscopic coverslip and the bacterial cell membrane was damaged after treatment with isookanin. The down-regulation of icaB and up-regulation of icaR were observed after treatment with isookanin. Additionally, the RNAIII gene was significantly up-regulated (p &lt; 0.0001) at the mRNA level. Molecular docking showed that isookanin could bind to biofilm-related proteins. This indicated that isookanin can affect biofilm formation at the initial attachment phase and the aggregation phase. The FICI index showed that the combination of isookanin and β-lactam antibiotics were synergistic and could reduce doses of antibiotics by inhibiting biofilm formation.DiscussionThis study improved the antibiotic susceptibility of S. epidermidis through inhibition of the biofilm formation, and provided a guidance for the treatment of antibiotic resistance caused by biofilm
The resource (in)sufficiency of the Caribbean: analyzing socio-metabolic risks (SMR) of water, energy, and food
Authors: Martin del Campo Francisco , Singh Simron Jit , Mijts Eric 
Published: May 2023

IntroductionSocio-metabolic risks (SMRs) are systemic risks associated with the availability of critical resources, the integrity of material circulation, and the distribution of their costs and benefits in a socio-ecological system. For resource-stressed systems like small island nations, understanding trade-offs and synergies between critical resources is not only crucial, but urgent. Climate change is already putting small islands at high risk through more frequent and intense extreme weather events, changing precipitation patterns, and threats of inundation with future sea-level rise.MethodsThis study compares the shifting resource-baseline for 14 Caribbean island nations for the year 2000 and 2017. We analyze water, energy, and food (WEF) and their nexus through the lens of SMRs, using indicators related to their availability, access, consumption, and self-sufficiency.ResultsOur findings point to the decreasing availability of all three resources within the Caribbean region. Meanwhile, between 2000 and 2017, consumption levels have increased by 20% with respect to water (from 230 to 275 m3/cap/yr) and primary energy (from 89 to 110 GJ/cap/yr), and 5% for food (from 2,570 to 2,700 kcal/cap/day). While universal access to these resources increased in the population, food and energy self-sufficiency of the region has declined.DiscussionCurrent patterns of resource-use, combined with maladaptive practices, and climate insensitive development—such as coastal squeeze, centralized energy systems, and trade policies—magnify islands' vulnerability. Disturbances, such as climate-induced extreme events, environmental changes, financial crises, or overexploitation of local resources, could lead to cascading dysfunction and eventual breakdown of the biophysical basis of island systems. This research is a first attempt at operationalizing the concept of SMRs, and offers a deeper understanding of risk-related resource dynamics on small islands, and highlights the urgency for policy response.
Chronic anemia is associated with systemic endothelial dysfunction
Authors: Chennupati Ramesh , Solga Isabella , Wischmann Patricia , Dahlmann Paul , Celik Feyza Gül , Pacht Daniela , Şahin Aslıhan , Yogathasan Vithya , Hosen Mohammad Rabiul , Gerdes Norbert , Kelm Malte , Jung Christian 
Published: May 2023

BackgroundIn acute myocardial infarction and heart failure, anemia is associated with adverse clinical outcomes. Endothelial dysfunction (ED) is characterized by attenuated nitric oxide (NO)-mediated relaxation responses which is poorly studied in chronic anemia (CA). We hypothesized that CA is associated with ED due to increased oxidative stress in the endothelium.MethodsCA was induced by repeated blood withdrawal in male C57BL/6J mice. Flow-Mediated Dilation (FMD) responses were assessed in CA mice using ultrasound-guided femoral transient ischemia model. Tissue organ bath was used to assess vascular responsiveness of aortic rings from CA mice, and in aortic rings incubated with red blood cells (RBCs) from anemic patients. In the aortic rings from anemic mice, the role of arginases was assessed using either an arginase inhibitor (Nor-NOHA) or genetic ablation of arginase 1 in the endothelium. Inflammatory changes in plasma of CA mice were examined by ELISA. Expression of endothelial NO synthase (eNOS), inducible NO synthase (iNOS), myeloperoxidase (MPO), 3-Nitrotyrosine levels, and 4-Hydroxynonenal (4-HNE) were assessed either by Western blotting or immunohistochemistry. The role of reactive oxygen species (ROS) in ED was assessed in the anemic mice either supplemented with N-Acetyl cysteine (NAC) or by in vitro pharmacological inhibition of MPO.ResultsThe FMD responses were diminished with a correlation to the duration of anemia. Aortic rings from CA mice showed reduced NO-dependent relaxation compared to non-anemic mice. RBCs from anemic patients attenuated NO-dependent relaxation responses in murine aortic rings compared to non-anemic controls. CA results in increased plasma VCAM-1, ICAM-1 levels, and an increased iNOS expression in aortic vascular smooth muscle cells. Arginases inhibition or arginase1 deletion did not improve ED in anemic mice. Increased expression of MPO and 4-HNE observed in endothelial cells of aortic sections from CA mice. NAC supplementation or inhibition of MPO improved relaxation responses in CA mice.ConclusionChronic anemia is associated with progressive endothelial dysfunction evidenced by activation of the endothelium mediated by systemic inflammation, increased iNOS activity, and ROS production in the arterial wall. ROS scavenger (NAC) supplementation or MPO inhibition are potential therapeutic options to reverse the devastating endothelial dysfunction in chronic anemia.