bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive and individualized surgical treatment strategy for distal tibia osteomyelitis: a retrospective study of 70 patients
Authors: Alimujiang Abudusalamu , Jia Qiyu , Guo Jian , Wu Tong , Zhang Jun , Wang Xi , Chen Guoqing , Ma Chuang 
Published: April 2023

Abstract
Background Distal tibia osteomyelitis (DTO) treatment has become a challenging problem due to its difficult treatment and special location. Our goal is to provide a comprehensive and individualized treatment strategy, and to investigate the associated complications.Methods We retrospectively analyzed the data of 70 patients with DTO diagnosed and treated in our hospital from January 2015 to January 2022. The average age was 42.5 years (12–73 years), there were 34 cases accompanied by bone defects, and the average length of the bone defect was 3.2 cm (2 cm–17 cm). We divided the patients into three groups based on infection severity and specific location: 25 cases of a simple type (S type), 23 cases of complex ankle non-involved type (CAN type), and 22 cases of complex ankle involved type (CAI type). Comprehensive individualized treatment, including debridement, reconstruction, arthrodesis, and other surgical methods, was performed on patients of various types, rehabilitation exercises were guided, and patients were closely monitored. The efficacy was assessed using the following criteria: (1) treatment and related complications; (2) infection and defect healing; (3) improvement of ADL, VAS, and AOFAS scores; (4) evaluation of patients undergoing Ilizarov distraction osteogenesis; and (5) evaluation of patients undergoing ankle arthrodesis.Results The follow-up time was 30 months (10–84 months). With the exception of three patients who required amputation due to aggravated infection and concomitant basic diseases, all patients achieved infection control and healing, and the complications were properly treated. Three scores of patients with different types were significantly improved, and the differences were statistically significant. Patients undergoing Ilizarov distraction osteogenesis had satisfactory results, and the superior rates of ASAMI bone evaluation and function evaluation were 89%. All patients with ankle arthrodesis finally achieved bone healing, and the average fusion time was 4.5 months (3–7 months).Conclusion The comprehensive individualized treatment strategy is reliable for the treatment of DTO, as it can guide individualized treatment under different conditions, solve the problem of bone and soft tissue defects while controlling infection, reduce complications and properly handle them, and save as much function of the affected limb as possible.
Application of Slam Method in Big Data Rural Tourism Management in Dynamic Scene
Authors: Hao Yingcheng , Zheng Lili 
Published: April 2023

Abstract
Under the background of the rapid development of science and technology, technologies in many fields are advancing accordingly. The same artificial intelligence and computer vision technologies are also constantly being updated. Similarly, in vision On the basis of, positioning and mapping (technology is the core technology for mobile robots to complete the intelligentization) has also had a great response in the academic and industrial circles, and has attracted the attention of most scholars. Today, the construction of smart tourism is in a prosperous stage. Based on the big data of rural tourism construction in a certain province, this article mainly uses the SLAM method that relies on visual characteristics under dynamic scenes to study the construction of rural tourism platform. In this paper, considering the influence of many factors, based on the ORB-SLAM2 system, a visual SLAM system is established. At the same time, the mathematical model of the SLAM system is established and used RGB-D The depth camera is used as the input sensor, the visual odometer locates the camera, the nonlinear optimization optimizes the data association, the closed-loop detection completes the camera repositioning, the map construction completes the environment description and other multi-module collaborations, which together complete the simultaneous positioning of the camera and the map Build work.
Design of financial management database for automobile enterprises based on image encryption algorithm
Authors: Gao Lin 
Published: April 2023

Abstract
The automobile industry has a history of more than 100 years in foreign countries, so it is the continuous progress of professional automobile enterprises that has promoted the continuous development of the automobile industry. Financial management and database system provide many automobile companies with the best financial management solutions in the industry. As the core of financial management, it is highly integrated with the fixed assets module, which makes the financial management in the information management system of automobile enterprises closely connected with the daily management of automobile enterprises. At present, the original data management of each unit in the financial management system of automobile enterprises is still not subject to regulatory control, and the financial responsibility and financial data are often inaccurate. The current financial system is not scientific in product pricing, and it is difficult to provide detailed and accurate cost analysis and difference analysis results. Finally, for automobile enterprises, a unified and integrated financial management database system should be used to better manage the financial and operating conditions of automobile companies. After outlining the general procedures of the encryption algorithm, this document introduces the security characteristics and sensitivity analysis of the image encryption algorithm key. The security of the image encryption algorithm is strengthened, and the encrypted image is checked separately. Based on this content, this paper analyzes the financial management system of automobile enterprises in general, and explains the process of fixed assets storage and special storage in the software. Then, by optimizing the overall structure design of financial management, the system design of financial management database is proposed. After understanding the shortcomings of current financial software in meeting user needs, the design objectives and tasks of financial management database are provided, and the system design of automobile financial management database is summarized, and the outlook after the system design is put forward.
Evaluation of tornadic environments and their trends and projected changes in Japan
Authors: Kawazoe Sho , Inatsu Masaru , Fujita Mikiko , Sugimoto Shiori , Okada Yasuko , Watanabe Shingo 
Published: April 2023

Abstract

Tornadoes are responsible for several high impact weather related disasters in Japan. However, little is known about how these events have changed over the last several decades or how they may change in future climates. This study examines environmental conditions associated with tornados in Japan using pseudo-soundings from the high-resolution fifth-generation ECMWF reanalysis. We first determine appropriate discriminators of F2 + tornadoes using thermodynamic (convective available potential energy, convective inhibition, lifting condensation level, and the K-index), kinematic (deep layer shear and storm-relative helicity), and multivariate tornado parameters (energy helicity index, K-helicity index, and the significant tornado parameter), and confirm that F2 + tornadoes occur in environments with higher instability and helicity, but are better distinguished using multivariate parameters. Recent trends indicate that in some of the most densely populated regions, F2 + environments have increased significantly over the last four decades. We also examined future changes for each parameter using a large ensemble 2-K warming experiment. Robust increases in strong tornado environments are depicted in many regions in Japan, particularly on the Sea of Japan side and the Kanto region. This indicates that despite projected decreases in deep layer shear and higher convective inhibition, significant increases in atmospheric instability compensate, leading to more days with F2 + tornado potential.
Evaluating skill in predicting the Interdecadal Pacific Oscillation in initialized decadal climate prediction hindcasts in E3SMv1 and CESM1 using two different initialization methods and a small set of start years
Authors: Meehl Gerald , Kirtman Ben , Glanville Anne A. , Richter Jadwiga , Rosenbloom Nan , Yeager Stephen 
Published: April 2023

Abstract

Having to run a large set of initialized hindcasts with many ensemble members for enough samples of start years to form a drifted climatology from which to compute anomalies to compare to observations (to quantify skill of the hindcasts) is a daunting computational challenge. This limits the ability to experiment with case studies and other applications where only a few initial years are needed. Here we run a set of hindcasts with CESM1 and E3SMv1 using two different initialization methods for a limited set of start years and use the respective uninitialized free-running historical simulations to form the model climatologies. Since the drifts from the observed initial states in the hindcasts toward the uninitialized model state are large and rapid, after a few years the drifted initialized models approach the uninitialized model climatological errors. Therefore, hindcasts from the limited start years can use the uninitialized climatology to represent the drifted model states after about lead year 3, providing a means to compute forecast anomalies in the absence of a large hindcast sample. There is comparable skill for predicting the Interdecadal Pacific Oscillation using this method compared to the conventional methodology with a large hindcast data set. The drifts are somewhat different in the two initialization methods, but the drifts are so large and consistent that by about lead year 3 the two methods are roughly comparable, though there is a model dependence to the drifts in the two initialization methods.
Gene Identification, Expression Analysis, and Molecular Docking of SAT/OASTL Reveal the Molecular Mechanisms of Selenocysteine Synthesis in Cardamine hupingshanensis
Authors: chen yushan , Luo Cihang , Liu Yi , Xiao Zhijing , Lu Yanke , Hou Zhi , Xiao Qiang , Zhou Yifeng , Tang Qiaoyu 
Published: April 2023

Abstract
Background A complex coupled with serine acetyltransferase (SAT) and O-acetyl serine (thiol) lyase (OASTL) is the key enzyme that catalyses selenocysteine synthesis in plants. The basic bioinformatics and functions of these two gene families have been reported for many plants in addition to Cardamine hupingshanensis, and the response of the ChSAT and ChOASTL family members under selenium stress has not been examined to date.Results In this study, genome-wide identification and comparative analysis of ChSAT and ChOASTL were performed. The eight genes from the ChSAT family were divided into three branches, and the thirteen genes from the ChOASTL family were divided into four branches by phylogenetic analysis and sequence alignment, indicating the evolutionary conservation of the gene structure and its association with other plant species. The expression of members in the ChSAT and ChOASTL families was studied under selenium stress, and ChSAT1;2 and ChOASTLA1;2 were upregulated by 9.4- and 7.4-fold, respectively, showing that these two proteins are involved in the synthesis of selenocysteine. Likewise, ChCS-like protein was upregulated by 8.8-fold, playing key roles in degradation. In addition, molecular docking simulations showed that ChOASTL binds to the test compound selenophosphate more strongly than selenide and sulfide, and the major motifs that bind the target compound are usually located at residues of amino acids Lys46, Gly181, Thr182, Gly183, Thr185 and Ser269.Conclusions This study revealed that selenophosphate was the optimal substrate of ChOASTL and participated in selenocysteine synthesis. The results of gene expression and molecular docking indicated that the ChSAT and ChOASTL genes were upregulated under selenium stress, and ChOASTL family genes could both synthesize and degrade cysteine/selenocysteine, which provided a theoretical basis for the regulation of selenocysteine synthesis.
WITHDRAWN: Genetic Diversity of Selected Ethiopian Core Tef [Eragrostis tef (Zucc.) Trotter] Germplasm Collections Using Morphological Traits
Authors: Adugna Derejaw Tesfa , Assefa Kebebew Assefa , Girma Dejene Girma , - Tileye Feyissa 
Published: April 2023

Abstract
Tef is an indigenous and important food, feed and cash crop to the small-holder of Ethiopian farmers. Information of the natural genetic variation of the crop would be useful for the genetic improvement of the crop through breeding. Hence, the current study was designed to determine the extent and pattern of genetic variability of selected tef core germplasm lines and released varieties from Ethiopia using morphological traits. A total of 81 tef genotypes were field evaluated for 17 morphological traits using a 9 × 9 simple lattice designs at Debre Zeit during the 2021 main cropping season and off-season. Only a few of the traits assessed showed significant differences among the genotypes. These were thousand seed weight and fertile tiller number in the main season, and peduncle length and number of fertile tillers in the off-season. Cluster analysis grouped the 81 tef genotypes into four clusters consisting of 15 to 31 genotypes. Principal component analysis showed that about 71% of the gross variance among the test genotypes was explained by six principal components with eigenvalues greater than one.
Effect of biological activity of Carapa procera DC. (Meliaceae) seed oil on the tomato leaf miner, Tuta absoluta Meyrick 1917 (Lepidoptera: Gelechiidae)
Authors: KONAN Kouassi Arthur Jocelin , N’CHO Anthelme J. , KOUADIO Marie-France N'da , GADJI André , COULIBALY Noupé D. , OUALI-N'GORAN Mauricette S-W. , MARTIN Thibaud 
Published: April 2023

Abstract
Tuta absoluta poses a serious threat to tomato production worldwide as it can cause more than 80% yield losses. Its control is currently mainly based on the use of synthetic chemical insecticides, which unfortunately selects resistant populations and entails public health risks. The aim of this study was to evaluate the insecticidal, repellent and sublethal effects of Carapa procera seed oil on all stages of T. absoluta. Larvicidal (by contact and by ingestion), ovicidal and anti-feeding effects were evaluated by testing 1.5%, 3%, 4.5%, 6% and 7.5% concentrations of oil. Larvicidal and ovicidal effects were tested by direct application of Carapa solutions on larvae and eggs but also by feeding the larvae leaves dipped in solutions. The adult repellent effect was investigated by identifying the preferred area on filter paper partly non-treated vs fully treated using LC10, LC50 et LC90 of larvae after ingestion. LC50 was also used on 2-day-old larvae to evaluate the sublethal effects on larval and pupal duration, longevity and adult morphology. Results showed that, regardless of the mode of application, all concentrations had larvicidal effects with a higher dose-response effect and a higher mortality rate via ingestion than via topical application. The ovicidal effect varied with the concentrations tested, the highest mortality rate was obtained at a concentration of 7.5%. At the same dose, Carapa oil reduced large feeding galleries from 92.22 ± 5.02% in controls to 3.33 ± 3.65% at the highest dose and had a repellent effect on 80% of adults. Carapa oil increased larval and pupal duration by 2.14 and 1.35 days, respectively, and reduced adult female longevity by 2.2 days and male longevity by 1.1 days. A deformation rate of 28.33% was observed in newly emerged adults. This study demonstrated insecticidal and insect repellent effects of Carapa oil on different stages of T. absoluta. This botanical oil is a very promising biopesticide to control this major new pest of Solanaceous crops. Its use in an agroecological pest management strategy is discussed.
Combination of percutaneous endoscopic lumbar discectomy and platelet-rich plasma hydrogel injection for the treatment of lumbar disc herniation
Authors: Zhang Lidong , Zhang Chengliang , Song Dajiang , Chen Gang , Liu Lei 
Published: April 2023

Abstract
Objective: To determine the safety and efficacy of percutaneous endoscopic lumbar discectomy (PELD) combined with platelet-rich plasma (PRP) hydrogel injection in patients with lumbar disc herniation (LDH).
Methods: A total of 98 consecutive patients with LDH who underwent either PELD combined with PRP hydrogel injection or PELD alone were reviewed. This retrospective study was performed between January 2019 and January 2021. Clinical outcomes were compared in the visual analog scale (VAS) for low back pain and leg pain, Oswestry disability index (ODI), Japanese Orthopaedic Association (JOA) scores, and MacNab criteria. Intervertebral disc height on MRI was measured and the Pfirrmann grade classification was used preoperatively and postoperatively.
Results: No severe adverse events were reported during an 18-month follow-up period. VAS scores for back pain were decreased at 1 month, 3 months, and 18 months in the treatment group than that in the control group. JOA score and ODI in the treatment group at 3 months and 18 months follow-up was lower than that in the control group (P <0.05). The excellent and good rate of the MacNab criteria was 92.0% (46/50) in the treatment group and 89.6% (43/48) in the control group (P >0.05). The comparation of Pffirmann grading and disc height at 18 months follow-up showed significant difference in two groups (P <0.05). The recurrence of LDH in the treatment group was lower than that in the control group (P <0.05).
Conclusions: We suggest that PELD combined with PRP hydrogel injection to treat patients with LDH is a safe and promising method. PRP injection was beneficial for disc remodeling after PELD and decreased the recurrence of LDH.
Analyzing the Performance of ChatGPT in Cardiology and Vascular Pathologies
Authors: Hariri Walid 
Published: April 2023

Abstract
The article aims to analyze the performance of ChatGPT, a large language model developed by OpenAI, in the context of cardiology and vascular pathologies. The study evaluated ChatGPT's accuracy in answering challenging multiple-choice questions (QCM) using a dataset of 190 questions from the Siamois-QCM platform. The goal was to assess ChatGPT's potential as a valuable tool in medical education compared to two well-ranked students of medicine. The results showed that ChatGPT outperformed the students, scoring 175 out of 190 correct answers with a percentage of 92.10\%, while the two students achieved scores of 163 and 159 with percentages of 85.78\% and 82.63\%, respectively.
Sex-specific metabolomics-derived blood biomarkers of Alzheimer’s disease
Authors: Clark Christopher , Laczko Endre , Rabl Miriam , Stojkovic Slavisa , Popp Julius 
Published: April 2023

Abstract
Readily accessible diagnostic tools are crucial for early detection of Alzheimer’s disease (AD). Here, we sought to identify peripheral metabolism biomarkers of cerebral AD pathology. Untargeted liquid chromatography-mass spectrometry was used to quantify 2286 serum metabolites in participants on a longitudinal memory clinic study. Unbiased between-group analysis using Orthogonal Partial Least Squares Discriminant Analysis, Linear Discriminant Analysis and Principal Component Analysis were performed to build a classifier for AD as indicated by CSF biomarkers. MetaboAnalyst was subsequently used for selection of the most relevant metabolites; pathway enrichment was performed to determine biological pathway alterations related to AD. No biomarker signature was found in the whole cohort. Stratification according to sex allowed building a classifier for AD using 14 metabolites in males and 9 in females that significantly improved the prediction of the presence of AD compared to a reference model. Thirteen enriched pathways were identified, including lipid and amino acid metabolisms. Compared to a reference model, the selected metabolites significantly improved the prediction of cognitive decline in females. Sex-specific peripheral metabolism biomarkers are useful to predict cerebral AD pathology and cognitive decline, and detect related pathway alterations. This highlights the need for personalised diagnostic and therapeutic approaches in AD.
Experimental ultrasonic probe positioning method using optical triangulation
Authors: Cygan Szymon 
Published: April 2023

Abstract
In ultrasonic imaging, including echocardiography, the location of the section view is defined manually. In case of research and development of speckle tracking methods using left ventricle phantoms the repeatability of probe positioning is crucial for acquired data interpretation. In this work an optical system and method for probe positioning are proposed. This systems consists of a set of two cameras, a calibration frame with 8 markers of with known coordinates and a probe holder with 4 markers. The described calibration process involves image segmentation and extraction of the camera projection matrices. The positioning method uses the same initial image processing steps followed by estimation of markers’ positions using the triangulation method. Performance of the system is tested using a validation plate with five coplanar markers. Obtained precision of positioning estimated based on the reprojection errors at each step of the process and as validation distance errors reaches approx. 2 mm, which is considered sufficient in case of ultrasonic imaging based on its resolution.
Seroprevalence and Molecular Detection of Herpes Simplex Virus Type-2 (HSV-2) among People living with HIV/AIDS in Northwestern, Nigeria
Authors: Muhammad Ibrahim Abubakar , Hafiz Taysir Ramadan , Muhammad Faisal , Reuben Rine Christopher , Sani TasiuAdamu , Adam AbubakarSunusi , Rogo LawalDahiru 
Published: April 2023

AbstractBackgroundIn most developing countries, including Nigeria, herpes simplex virus type 2 (HSV-2) is associated with an increased risk of HIV acquisition and transmission, which often results in more frequent, lasting, and severe clinical outcomes. Despite the association between HSV-2 and HIV, knowledge regarding HSV-2 among people living with HIV/AIDS (PLWHA) in northern Nigeria is elusive.MethodsThis cross-sectional study sought to determine the seroprevalence and molecular detection of HSV-2 among PLWHA attending a referral hospital in Northwestern Nigeria. Blood samples collected from 180 PLWHA were screened for HSV-2 IgM using Enzyme-Linked Immunosorbent Assay (ELISA) and then subjected to molecular characterization using HSV-2 specific PCR. Moreover, socio-demographic data and risk factors of the sampled population were collected using a structured questionnaire.ResultsThe overall seroprevalence of HSV-2 was 6.1%, with 5.0% and 1.1% in females and males, respectively. However, no significant association (P > 0.05) existed between HSV-2 seroprevalence with marital status, gender, occupation, residence, educational level, age, history of sexually transmitted diseases (STDs), ethnicity, and the number of sex partners. In addition, condom use significantly (P < 0.05) reduced the risk of HSV-2 infection among the study population. However, only 5 (45.45%) of the 11 (100.0%) HSV-2 seropositive subjects were molecularly confirmed to be HSV-2 positive using PCR.ConclusionThis is the first study to confirm the presence of HSV-2 infection among PLWHA in Northwestern Nigeria. Data obtained stress the need for surveillance of HSV-2 therapy, and public enlightenment on the use of condoms to reduce the risk of HIV transmission.