bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graft impingement increases anterior cruciate ligament graft signal more than acute graft bending angle: magnetic resonance imaging‐based study in outside‐in anterior cruciate ligament reconstruction
Authors: Park Seong Yun , Cho Joon Hee , Ho Jade Pei Yuik , Tu Nguyen Thanh , Kim Yong Beom , Lee Yong Seuk 
Published: June 2023

AbstractPurposeIn this study, the relationship between patient‐specific geometric factors and tunnel placement in graft impingement was identified by using magnetic resonance imaging (MRI) signal intensity of anterior cruciate ligament (ACL) grafts.MethodsNinety‐two patients, who were treated between 2014 and 2020, were included retrospectively. These patients underwent primary remnant‐preserving outside‐in ACL reconstruction (ACLR) and were followed up with postoperative MRI at least one year after surgery. Plain radiographs and computed tomography (CT) were used to analyze tibial and femoral tunnel positions. Postoperative MRI was performed, at 32.8 ± 17.5 months after surgery, to evaluate the graft signal intensity, the ACL/posterior cruciate ligament (PCL) ratio (APR), ACL/muscle ratio (AMR), tunnel positions, and graft impingement. Clinical and stability outcomes were analyzed using the International Knee Documentation Committee (IKDC) subjective and objective scores, Lysholm scores, and side‐to‐side differences (SS‐D).ResultsThe mean APR and AMR of the proximal third of the grafts were significantly lower than those of the middle third of the grafts (p = 0.017 and p = 0.045, respectively). Multivariate regression analysis showed that there was a negative association between the mean APR and AMR of entire intra‐articular ACL graft and the distance from the anterior end of the intercondylar roof to the center of the tibial tunnel in the sagittal plane (p < 0.001 and p < 0.001, respectively) and the notch width index (p < 0.001 and p = 0.002, respectively). No significant correlations were found between tunneling and geometric factors, and clinical scores or SS‐D.ConclusionsGraft impingement on the anterior tibial tunnel relative to the end of the intercondylar roof and narrow notch was a more significant contributing factor on increased signal intensities of the ACL graft, compared with the acute femoral bending angle in remnant‐preserving outside‐in ACLR. Therefore, surgeons should focus on intercondylar notch anatomy during tibial tunnel placement to avoid roof impingement.Level of evidenceLevel III.
Judd–Ofelt and photoluminescence analysis of Nd2O3-doped within host fluoroborate glass from the system B2O3–NaF–La2O3
Authors: Marzouk M. A. , ElBatal F. H. , Hamdy Y. M. , ElBatal H. A. 
Published: June 2023

AbstractUndoped glass of chemical composition 70B2O3–25NaF–5La2O3together with Nd2O3-doped samples were prepared via conventional melt and annealing procedure. The prepared glasses were investigated through photoluminescence measurements to find out their extent for the lasing application. The undoped sample reveals two UV absorption peaks while Nd2O3-doped samples show 10 well-characterized peaks in the UV–Visible range that are correlated to different transition states of Nd3+ions. Three different bands are detected in the emission spectra at 875 nm (4F3/2 → 4I9/2), 1056 nm (4F3/2 → 4I11/2), and 1326 nm (4F3/2 → 4I13/2). The Judd–Ofelt parameters (Ω2, Ω4, Ω6) and radiative properties were estimated using the Judd–Ofelt theory. The represented data indicated that the transition line4F3/2 → 4I11/2is the sharpest and lowest bandwidth value than other detected transitions. The structural analysis by FTIR vibrational modes suggested that the IR absorption bands within the range 800–1200 cm−1originate from both combined vibrations of tetrahedral (BO4) and (BO3F) groups together with (NaF4) groups beside triangular BO3groups which are vibrating within the range 1200–1600 cm−1. The addition of Nd2O3is assumed to cause the possible transformation of some structural B–O bonds within the range of triangular borate units referring to the possible formation of pyroborate units or similar structural groups.
Urology during Afghanistan mission: lessons learned and implications for the future
Authors: Schoch Justine , Matthies Cord , Heidenreich Holger , Diehm Jens , Schmelz Hans , Ruf Christian , Nestler Tim 
Published: June 2023

Abstract
Purpose
Battle-related trauma is common in modern warfare and can lead to genitourinary injuries. In Western countries, urogenital injuries are rare in the civilian environment. The main objective of this study was to assess urological workload for surgeons on deployment.

Material and methods
Data were acquired over a period of five years of deployment in a U.S. facility in Afghanistan.

Results
German urological surgeons treated on average one urologic outpatient per day and performed 314 surgical interventions overall. Surgical interventions were categorized as battle-related interventions (BRIs, n = 169, 53.8%) and nonbattle-related interventions (non-BRIs, n = 145, 46.2%). In the BRI group, interventions were mainly performed on the external genitalia (n = 67, 39.6%), while in the non-BRI group, endourological procedures predominated (n = 109). This is consistent with a higher rate of abdominal or pelvic procedures performed in the BRI group (n = 51, 30.2%).
Furthermore, the types of interventions performed on the external genitalia differed significantly. In the BRI group, 58.2% (n = 39) of interventions were scrotal explorations, but none of those procedures were performed in the non-BRI group (p < 0.001). However, 50.0% (n = 13) of scrotal explorations in the non-BRI group were due to suspected torsions of the testes followed by orchidopexy (BRI: n = 1, 1.5%, p < 0.001). Concerning outpatients, the consultation was mainly due to complaints concerning the external genitalia (32.7%, n = 252) or kidney/ureteral stones (23.5%, n = 181).

Conclusion
While the treatment of urological outpatients in a deployment setting resembles the treatment of soldiers in Germany, BRIs requires abdominal/retroperitoneal urosurgical skills and basic skills in reconstructive surgery.
Detecting linear trend changes in data sequences
Authors: Maeng Hyeyoung , Fryzlewicz Piotr 
Published: June 2023

AbstractWe propose TrendSegment, a methodology for detecting multiple change-points corresponding to linear trend changes in one dimensional data. A core ingredient of TrendSegment is a new Tail-Greedy Unbalanced Wavelet transform: a conditionally orthonormal, bottom-up transformation of the data through an adaptively constructed unbalanced wavelet basis, which results in a sparse representation of the data. Due to its bottom-up nature, this multiscale decomposition focuses on local features in its early stages and on global features next which enables the detection of both long and short linear trend segments at once. To reduce the computational complexity, the proposed method merges multiple regions in a single pass over the data. We show the consistency of the estimated number and locations of change-points. The practicality of our approach is demonstrated through simulations and two real data examples, involving Iceland temperature data and sea ice extent of the Arctic and the Antarctic. Our methodology is implemented in the R package , available from CRAN.
Building a FAIR image data ecosystem for microscopy communities
Authors: Kemmer Isabel , Keppler Antje , Serrano-Solano Beatriz , Rybina Arina , Özdemir Buğra , Bischof Johanna , El Ghadraoui Ayoub , Eriksson John E. , Mathur Aastha 
Published: June 2023

AbstractBioimaging has now entered the era of big data with faster-than-ever development of complex microscopy technologies leading to increasingly complex datasets. This enormous increase in data size and informational complexity within those datasets has brought with it several difficulties in terms of common and harmonized data handling, analysis, and management practices, which are currently hampering the full potential of image data being realized. Here, we outline a wide range of efforts and solutions currently being developed by the microscopy community to address these challenges on the path towards FAIR bioimaging data. We also highlight how different actors in the microscopy ecosystem are working together, creating synergies that develop new approaches, and how research infrastructures, such as Euro-BioImaging, are fostering these interactions to shape the field.
Micro-paper-based analytical device decorated with metal-organic frameworks for the assay of synthetic cannabinoids in oral fluids coupled to ion mobility spectrometry
Authors: Martínez-Pérez-Cejuela Héctor , García-Atienza Patricia , Simó-Alfonso Ernesto Francisco , Herrero-Martínez José Manuel , Armenta Sergio 
Published: June 2023

AbstractA new concept of paper-based device has been developed combining the advantages of cellulose supports and the rich surface chemistry of metal-organic frameworks (MOFs). The composite, named as NH2-UiO-66@paper, has been developed for the isolation of synthetic cannabinoid receptor agonists (SCRAs) in oral fluids, trying to mimic the interactions of those compounds with the human CB1R and CB2R receptors, mainly governed by hydrogen bonding and π-interactions with serine and histidine residues. MOF selection (UiO-66) and functionalization of the ligand (2-aminoterephthalic acid) has been done according to the following criteria: (i) water stability of the selected MOF, and (ii) promoting appropriate interactions with SCRAs due to the MOF nature. NH2-UiO-66@paper composite has been characterized in depth and the results confirmed that the material is stable at the temperature selected for thermal desorption (230 °C). Furthermore, the developed method provided appropriate precision values (RSD < 12%) and a limit of detection as low as 10 ng using ion mobility spectrometry as analytical technique. Lastly, the method has been successfully applied to the isolation of several synthetic cannabinoids from oral fluids. This method claims to be an interesting approach for expanding the combination of MOFs with sustainable support and represents a promising alternative to sophisticated and non-portable systems due to the negligible sample treatment required and the simplicity of the operation, which can be applied with screening purposes.
Graphical abstract
Global analysis of land-use changes in karst areas and the implications for water resources
Authors: Zhang Jiawen , Liesch Tanja , Chen Zhao , Goldscheider Nico 
Published: June 2023

AbstractKarst areas contain valuable groundwater resources and high biodiversity, but are particularly vulnerable to climate change and human impacts. Land-use change is the cause and consequence of global environmental change. The releases of the Climate Change Initiative-Land Cover (CCI-LC) and World Karst Aquifer Map (WOKAM) datasets have made it possible to explore global land-use changes in karst areas. This paper firstly analyses the global karst land-use distribution in 2020, as well as the land-use transition characteristics between 1992 and 2020. Then, two indicators, proportion of land-use change and dominant type of land-use change, are proposed to identify the spatial characteristics of land-use change in global karst areas. Finally, three examples of land-use change in karst areas are analyzed in detail. Land-use types and proportions of the global karst areas from large to small are as follows: forest (31.78%), bare area (27.58%), cropland (19.02%), grassland (10.87%), shrubland (7.21%), wetland (1.67%), ice and snow (1.16%) and urban (0.71%). The total area of global karst land-use change is 1.30 million km2, about 4.85% of global karst surface. The land-use change trend of global karst is dominated by afforestation, supplemented by scattered urbanization and agricultural reclamation. The tropical climate has a higher intensity of land-use change. Regions of agricultural reclamation are highly consistent with the population density. These results reflect the impact of human activities and climate change on land-use changes in global karst areas, and serve as a basis for further research and planning of land resource management.
Scientific workflow execution in the cloud using a dynamic runtime model
Authors: Erbel Johannes , Grabowski Jens 
Published: June 2023

AbstractTo explain specific phenomena, scientists perform a sequence of tasks, e.g., to gather, analyze and interpret data, forming a scientific workflow. Depending on the complexity of the workflow, scientists require access to various kinds of tools, applications and infrastructures for individual tasks. Current approaches are often limited to managing these resources at design time, requiring the scientist to preemptively set up applications essential for their workflow. Therefore, a dynamic provisioning and configuration of computing resources are required that fulfills these needs at runtime. In this paper, we present a dynamic runtime model that couples workflow tasks with their individual applications and infrastructure requirements. This runtime model is used as a knowledge base by a model-driven workflow execution engine orchestrating the sequence of tasks and their infrastructure. We exhibit that the simplicity of the runtime model supports the creation of highly tailored infrastructures, the integration of self-developed applications, as well as a human-in-the-loop allowing scientists to monitor and interact with the workflow at runtime. To tackle the heterogeneity of cloud provider interfaces, we implement the workflow runtime model by extending the Open Cloud Computing Interface cloud standard, which provides an extensible data model as well as a uniform interface to manage cloud resources. We demonstrate the applicability of our approach using three case studies and discuss the benefits of the runtime model from a user and system perspective.
Volume Optimisation of Multi-stable Origami Bellows for Deployable Space Habitats
Authors: Yang Mengzhu , Defillion Joe , Scarpa Fabrizio , Schenk Mark 
Published: June 2023

AbstractOrigami bellows are formed by folding flat sheets into closed cylindrical structures along predefined creases. As the bellows unfold, the volume of the origami structure will change significantly, offering potential for use as inflatable deployable structures. This paper presents a geometric study of the volume of multi-stable Miura-ori and Kresling bellows, focusing on their application as deployable space habitats. Such habitats would be compactly stowed during launch, before expanding once in orbit. The internal volume ratio between different deployed states is investigated across the geometric design space. As a case study, the SpaceX Falcon 9 payload fairing is chosen for the transportation of space habitats. The stowed volume and effective deployed volume of the origami space habitats are calculated to enable comparison with conventional habitat designs. Optimal designs for the deployment of Miura-ori and Kresling patterned tubular space habitats are obtained using particle swarm optimisation (PSO) techniques. Configurations with significant volume expansion can be found in both patterns, with the Miura-ori patterns achieving higher volume expansion due to their additional radial deployment. A multi-objective PSO (MOPSO) is adopted to identify trade-offs between volumetric deployment and radial expansion ratios for the Miura-ori pattern.
Rushes as a phytoindicator of a lake’s surrounding land use
Authors: Maślanko Weronika , Sender Joanna , Różańska-Boczula Monika 
Published: June 2023

AbstractRushes belong to the group of plants commonly found in water bodies, fulfilling many important functions. However, their presence depends both on features of the immediate surroundings and morphology of the lake. At the same time, rush presence can be an indicator of important features of the surrounding habitats. The aim of this study was to determine the impact of shoreline and buffer zone development on the attributes of rushes. Indications of lake features affected the rushes most strongly. We analysed 65 lakes located in the eastern part of Poland, within the boundaries of the Łęczna-Włodawa Lake District. The multidimensional analyses identified factors that most strongly determined the development of lake rushes in Polesie Lubelskie. The presence of peat bogs, scrubland communities, and wet meadows favoured the development of rushes. Among the morphometric characteristics of lakes, the depth and frequency of water mixing were significant, as well as the trophic level of the lake. Moreover, models describing scenarios for further development of rushes were developed. They predicted that the surface area of the rushes in the lake will increase (average of 0.288 ha) when the peatlands become overgrown 1 ha, and the share of dry (drained) meadows will increase (average of 0.996 ha) in the buffer zone. The increase in the density of rushes will take place if the share of buildings and scrub communities increases both in the buffer zone and shoreline area.
Rickettsia africae and other unclassified Rickettsia species of the spotted fever group in ticks of the Western Ghats, India
Authors: Babu N Naren , Jayaram Anup , Auti Amogh Milind , Bhandari Yuvraj , Shetty Ujwal , Arunkumar Govindakarnavar 
Published: June 2023

AbstractThe spotted fever group (SFG) of Rickettsia are zoonotic disease-causing pathogens, commonly transmitted by hard ticks to a wide range of hosts, including humans. Rickettsia conorii is the common SFG recognised in India, whereas most of the infections due to other group species go undifferentiated at the species level. Hence, this study was conducted to screen host-seeking ticks in the Western Ghats region, India, for the DNA of SFG Rickettsia. The ticks were collected from Kerala, Goa, and Maharashtra states of India during a survey conducted between November 2017 and January 2018. In total, 288 tick pools were screened for Rickettsia spp. DNA using pan-Rickettsia real-time PCR, and conventional PCR targeting the gltA, OmpA and 17-kDa protein-coding genes. Nucleotide sequences were subjected to phylogenetic analysis using the NCBI BLAST tool to identify submitted sequences with higher homology. Neighbour-joining trees were constructed using the reference sequences of the GenBank database. Overall, Rickettsia spp. DNA was detected in 27.2% (62/228 pools) of host-seeking ticks across the Western Ghats region, with an estimated minimum infection rate of 0.057. Upon phylogenetic analysis, it was identified that the detected sequences were highly similar (> 99% sequence homology) to R. africae, Candidatus R. laoensis and an un-categorised Rickettsia species, and they were widely carried by Haemaphysalis ticks. The current study is the first report of R. africae and Candidatus R. laoensis in ticks in India. Although the pathogenicity of these species is not well documented, they may pose a potential threat to both animal and the human population in this geographical region.
Mining legal arguments in court decisions
Authors: Habernal Ivan , Faber Daniel , Recchia Nicola , Bretthauer Sebastian , Gurevych Iryna , Spiecker genannt Döhmann Indra , Burchard Christoph 
Published: June 2023

AbstractIdentifying, classifying, and analyzing arguments in legal discourse has been a prominent area of research since the inception of the argument mining field. However, there has been a major discrepancy between the way natural language processing (NLP) researchers model and annotate arguments in court decisions and the way legal experts understand and analyze legal argumentation. While computational approaches typically simplify arguments into generic premises and claims, arguments in legal research usually exhibit a rich typology that is important for gaining insights into the particular case and applications of law in general. We address this problem and make several substantial contributions to move the field forward. First, we design a new annotation scheme for legal arguments in proceedings of the European Court of Human Rights (ECHR) that is deeply rooted in the theory and practice of legal argumentation research. Second, we compile and annotate a large corpus of 373 court decisions (2.3M tokens and 15k annotated argument spans). Finally, we train an argument mining model that outperforms state-of-the-art models in the legal NLP domain and provide a thorough expert-based evaluation. All datasets and source codes are available under open lincenses athttps://github.com/trusthlt/mining-legal-arguments.
Small Extracellular Vesicles from Periodontal Ligament Stem Cells Primed by Lipopolysaccharide Regulate Macrophage M1 Polarization via miR-433-3p Targeting TLR2/TLR4/NF-κB
Authors: Cui Shuyue , Zhang Zijie , Cheng Chen , Tang Shuai , Zhai Mingrui , Li Lan , Wei Fulan , Ding Gang 
Published: June 2023

Abstract—Lipopolysaccharide (LPS) is regarded as the main pathogenic factor of periodontitis. Mesenchymal stem cell–derived small extracellular vesicles (sEVs) play a key role in a variety of physiological and pathological processes. This study investigated the effects of sEVs derived from periodontal ligament stem cells (PDLSCs) pretreated with LPS on macrophage polarization and the underlying mechanisms. PDLSCs were treated with LPS (1 µg/mL) for 24 h, and sEVs were harvested by gradient centrifugation method. Macrophages were incubated with sEVs for 24 h, followed by examination of the expression profiles of inflammatory and anti-inflammatory cytokines, and polarization markers. Furthermore, microarray analysis, western blot test, and microRNA inhibitor transfection experiments were used to elucidate the molecular signaling pathway responsible for the process. The results showed that sEVs derived from LPS-preconditioning PDLSCs could significantly increase the expression of M1 markers and inflammatory cytokines, whereas decreased the expression of M2 markers and anti-inflammatory cytokines. Mechanistic analysis showed that TLR2/TLR4/NF-κB p65 pathway was involved in M1 polarization of macrophages, and microRNA-433-3p played a role, at least in part, in the course. Collectively, LPS could promote the macrophages into M1 status via TLR2/TLR4/NF-κB p65 signaling pathway partly by sEV-mediated microRNA-433-3p, which could be a potential therapeutic target for periodontitis.
Jews “Holding the Keys to the Church” and the Posthumous Career of Zelman Wolfowicz of Drohobych
Authors: Wiślicz Tomasz 
Published: June 2023

AbstractAt the end of the nineteenth century in the historiography and popular writing of the three nationalities living in what was then Habsburg Galicia—Polish, Jewish, and Ukrainian—there was an ongoing debate about the motif of the alleged leasing of Orthodox churches by Jews in the seventeenth and eighteenth centuries. The motif of the Jews “holding the keys to the church” was intended, in its own way, to justify the anti-Jewish nature of the Khmelnytsky Uprising of 1648, as well as later rebellions in Ukraine. The problem, however, was that most testimonies of such practices came from literary rather than historical sources. Therefore, the discovery in the archival sources of the character of Zelman Wolfowicz (ca. 1680–1757) from Drohobych, a factor of the starostess Dorota Tarłowa and an informal administrator of the estate, who was sentenced to death for all kinds of economic and criminal offences against the population of the demesne, could have held the key evidence confirming the thesis of the oppression of the Ukrainian people by Jewish leaseholders under the authority of the Polish-Lithuanian Commonwealth. In Zelman Wolfowicz’s case, no confirmation was found that he ever “held the keys to the church.” Nevertheless, he was associated with this practice by means of a misread and misunderstood folk song, whose hero happened to bear the same name: Zelman. The power of legend, combined with antisemitic stereotypes, has caused both historiography and ethnography to bolster this image while ignoring the source evidence.