bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Value IRS-1 rs1801278G > A Polymorphism Testing in Evaluating
Infertile Women with Polycystic Ovarian Syndrome: A Case-control
Study
Authors: Raad Helmi Zeena , Nori Wassan , Ghani Zghair Muna Abdul 
Published: September 2023

Background:
Polycystic ovary syndrome (PCOS) is a leading cause of infertility. Insulin
resistance is a key element in pathogenesis. The insulin receptor causes phosphorylation of the insulin
receptor substrate (IRS); IRS-1 rs1801278G > A polymorphism variant is the most common genetic
variant associated with IR and PCOS.

Objective:
We aimed to examine the frequency of IRS-1 rs1801278G > A polymorphism variant and
test its value in evaluating infertile PCOS women.

Methods:
A case-control study recruited 140 age and body-mass-matched participants in the university
hospital, subdivided according to Rotterdam criteria into PCOS cases (70/140) and healthy controls
(70/140). We collected demographic data, ultrasonic [antral follicles and endometrial thickness], hormonal
[FSH, LH, AMH, E2], and genetic data by polymerase chain reaction for analysis.

Result:
Wild GG SNP rs1801278 G was meaningfully higher among controls (58.57%, P<0.0001).
Mutant AA SNP rs1801278 was significantly higher in PCOS women (37.14%, P-value =0.0001, an
odds ratio of 20.50, 95% CI (9.42-28.63) to develop PCOS. Heterogenous GA gene SNP rs1801278
showed a trend of higher frequency in PCOS patients with 44.29%; OR of 3.91, 95% CI (1.37–7.55);
P = 0.422. Upon correlating infertility parameters to SNP rs1801278 G>A polymorphism, statistical
differences were found with AFC, LH/FSH ratio, and serum testosterone. As for the AMH, E2, and
endometrial thickness, they failed to have a statistical value.

Conclusion:
The significant correlation of genetic polymorphism to infertility parameters among
PCOS women opens a new therapeutic and prognostic avenue that helps gynecologists tailor manganate
for a better and safer outcome.
Analytical Methodologies for the Estimation of Acyclovir as Key
Members of Anti-viral Agent: Two Decades in Review
Authors: Gupta Akhil , Pathak Shilpi 
Published: September 2023

Abstract:
Herpes simplex virus (HSV) is a viral infection that primarily targets oral and genital organs in humans. Acyclovir is a widely prescribed anti-viral agent used in the infection caused by herpes simplex virus (HSV). This article emphasizes several analytical techniques, including spectrophotometry, High-performance liquid chromatography, High-performance thin-layer liquid chromatography, Ultra performance liquid chromatography, and Liquid chromatography/Mass detection for the quantification of acyclovir in different matrices like biological fluids and Pharmaceutical formulation. In the proposed work, numerous methods for different techniques were extracted from various databases such as Science Direct, Springer, PubMed, SCOPUS, Web of Science, etc. According to the recommendation from the internal conference on harmonization, this review describes how to determine the presence of utilizing acyclovir in different analytical techniques alone or in combination with another drug.
Predicting Readmission of Cardiovascular Patients Admitted to the CCU using Data Mining Techniques
Authors: Salimi Marzie , Bastani Peivand , Nasiri Mahdi , Karajizadeh Mehrdad , Ravangard Ramin 
Published: September 2023

Background:
Cardiovascular (CV) diseases account for a large number of readmissions.

Objective:
Using data mining techniques, we aimed to predict the readmission of CV patients to Coronary Care Units of 4 public hospitals in Shiraz, Iran, within 30 days after discharge.

Methods:
To identify the variables affecting the readmission of CV patients in the present cross-sectional study, a comprehensive review of previous studies and the consensus of specialists and sub-specialists were used. The obtained variables were based on 264 readmitted and non-readmitted patients. Readmission was modeled with predictive algorithms with an accuracy of >70% using the IBM SPSS Modeler 18.0 software. Cross-Industry Standard Process for Data Mining (CRISP-DM) methodology provided a structured approach to planning the project.

Results:
Overall, 47 influential variables were included. The Support Vector Machine (SVM), Chi-square Automatic Interaction Detection (CHIAD), artificial neural network, C5.0, K-Nearest Neighbour, logistic regression, Classification and Regression (C&R) tree, and Quest algorithms with an accuracy of 98.60%, 89.60%, 89.90%, 88.00%, 85.90%, 79.90%, 78.60%, and 74.40%, respectively, were selected. The SVM algorithm was the best model for predicting readmission. According to this algorithm, the factors affecting readmission were age, arrhythmia, hypertension, chest pain, type of admission, cardiac or non-cardiac comorbidities, ejection fraction, undergoing coronary angiography, fluid and electrolyte disorders, and hospitalization 6-9 months before the current admission.

Conclusion:
According to the influential variables, it is suggested to educate patients, especially the older ones, about following physician advice and also to teach medical staff about up-to-date options to reduce readmissions.
Markerless Motion Capture to Quantify Functional Performance in Neurodegeneration: Systematic Review (Preprint)
Authors: Jeyasingh-Jacob Julian , Crook-Rumsey Mark , Shah Harshvi , Joseph Theresita , Abulikemu Subati , Daniels Sarah , Sharp David J , Haar Shlomi 
Published: September 2023

BACKGROUND

Markerless motion capture (MMC) uses video cameras or depth sensors for full body tracking and presents a promising approach for objectively and unobtrusively monitoring functional performance within community settings, to aid clinical decision-making in neurodegenerative diseases such as dementia.

OBJECTIVE

The primary objective of this systematic review was to investigate the application of MMC using full-body tracking, to quantify functional performance in people with dementia, mild cognitive impairment, and Parkinson disease.

METHODS

A systematic search of the Embase, MEDLINE, CINAHL, and Scopus databases was conducted between November 2022 and February 2023, which yielded a total of 1595 results. The inclusion criteria were MMC and full-body tracking. A total of 157 studies were included for full-text screening, out of which 26 eligible studies that met the selection criteria were included in the review.

RESULTS

Primarily, the selected studies focused on gait analysis (n=24), while other functional tasks, such as sit to stand (n=5) and stepping in place (n=1), were also explored. However, activities of daily living were not evaluated in any of the included studies. MMC models varied across the studies, encompassing depth cameras (n=18) versus standard video cameras (n=5) or mobile phone cameras (n=2) with postprocessing using deep learning models. However, only 6 studies conducted rigorous comparisons with established gold-standard motion capture models.

CONCLUSIONS

Despite its potential as an effective tool for analyzing movement and posture in individuals with dementia, mild cognitive impairment, and Parkinson disease, further research is required to establish the clinical usefulness of MMC in quantifying mobility and functional performance in the real world.
Characterization of Carrageenan Edible Film With Natural Antioxidant From Syzygium Cumini Leaf Extract (SCLE)
Authors: Nasution Reni Silvia 
Published: September 2023

Abstract: Edible film have received considerable attention because of their advantages including their use as edible packaging material over synthetic films. This study aimed to characterize an edible film based on carrageenan and Syzygium cumini leaf extract (SCLE) as a natural antioxidant. The addition of SCLE was carried out with various concentrations of 0, 5, 10 and 15%. Characterization was carried out by measuring the physical properties, mechanical properties and antioxidant activities. The result showed that the presence of SCLE gave an increase in thickness and a decrease in solubility and water content compared to the edible film without the addition of SCLE. The addition of 5% SCLE resulted in a slight increase in tensile strength and a reduction in elongation at break. The edible films also showed an increase in antioxidant activity with the addition of SCLE where the highest antioxidant activity was at the addition of 15% SCLE. The incorporation of natural antioxidants in edible films can be a potential strategy to produce promising active packaging to extend product shelf life in the food packaging industry.Abstrak: Edible film telah mendapat banyak perhatian karena keuntungannya sebagai kemasan yang dapat dimakan dibandingkan film sintetik. Tujuan dari penelitian ini adalah untuk mengkarakterisasi edible film berbasis karaginan dan ekstrak daun Syzygium cumini (SCLE) sebagai antioksidan alami. Penambahan SCLE dilakukan dengan variasi konsentrasi 0, 5, 10 dan 15%. Karakterisasi dilakukan dengan mengukur sifat fisika, sifat mekanik dan aktivitas antioksidannya. Hasil menunjukkan bahwa keberadaan SCLE memberikan peningkatan pada ketebalan dan penurunan pada kelarutan dan kadar air dibandingkan edibe film tanpa penambahan SCLE. Penambahan SCLE sebanyak 5% menghasilkan sedikit peningkatan pada kuat tarik dan pengurangan pada perpanjangan putus. Edible film juga menunjukkan peningkatan aktivitas antioksidan dengan penambahan SCLE dimana aktivitas antioksidan tertinggi pada penambahan 15% SCLE. Penggabungan antioksidan alami pada edible film dapat menjadi strategi potensial untuk menghasilkan kemasan aktif yang menjanjikan untuk memperpanjang umur simpan produk pada industri kemasan makanan.
Recent Research on the Identification, Assessment, and Response to Fraud Risks: Implications for Audit Practice and Topics for Future Research
Authors: Brazel Joseph F. , Carpenter Tina , Gimbar Christine , Jenkins J. Gregory , Jones Keith L. 
Published: September 2023

SYNOPSIS
The financial statement auditor’s identification of fraud risk factors, their assessment of fraud risk, and their fraud risk responses are key to the auditor’s consideration of fraud and fraud detection. Given that the last review of research related to the search for fraud during the audit occurred nearly a decade ago, we provide a summary of recent academic research to update and inform practitioners, researchers, standard setters, regulators, and other stakeholders in the financial reporting process. We categorize and summarize findings from recent academic studies that focus on the auditor’s identification, assessment, and responses to fraud risks. Implications for practice are presented for each of these areas, along with topics and questions for future research.
JEL Classifications: M40; M41; M42; M48.
Divvying Up Data: A Data Analytics Case
Authors: Seymoure Suzanne M. , Ozlanski Michael E. 
Published: September 2023

ABSTRACT
This case asks students to assume the role of a newly hired (data) analyst for Divvy, Chicago’s bike share program. In this role, they use data analytics software to perform data analysis and data visualization techniques. This case can be implemented in multiple parts, and it is scalable for the unique needs of instructors and their students. Introductory topics include assessing the properties of the data, describing data validation techniques, creating calculated variables, and constructing basic data visualizations. Advanced topics include joining additional data sources, developing and investigating research questions, and creating dashboards to tell a meaningful story about the data. The case is unique because it enables students to interact with a large, real-world dataset, and it is ideal for accounting information systems or data analytics courses.
Exploring the Impact of Technology Dominance on Audit Professionalism through Data Analytic-Driven Healthcare Audits
Authors: Koreff Jared , Baudot Lisa , Sutton Steve G. 
Published: September 2023

ABSTRACT
Artificial intelligence (AI)-enabled tools and analytics hold the potential to radically alter audit processes by disseminating centralized audit expertise. We examine this potential in the context of data analytic-driven audits mandated to reduce fraud, waste, and abuse in a government-sponsored healthcare program. To do so, we draw on semistructured interviews with healthcare providers (i.e., auditees) subject to healthcare audits. Our work shows how use of paraprofessional auditors guided by AI-enabled tools and analytics reflects a very different audit environment. Specifically, auditees’ experiences suggest paraprofessional auditors lack specific expertise and credentials to conduct data-driven audits, apply judgment in deference to technology, and disregard the impact of AI-driven decisions on the public interest. Such experiences raise potential concerns for all audits over unbridled use of AI-enabled tools and analytics by novice-level auditors/paraprofessionals, but even more for audits conducted in contexts where adherence to professional norms is essential to minimizing public interest consequences.
JEL Classifications: M42; M48.
How Do Individual Analyst Characteristics Affect Analyst Performance?
Authors: Bratten Brian , Larocque Stephannie 
Published: September 2023

ABSTRACT
Motivated by research from the late 1990s and early 2000s, researchers often examine analyst performance as a function of individual analyst characteristics using variables representing analysts’ experience, busyness, and resources. Studies make different choices for variable construction and fixed effects, sometimes with varying results, suggesting there is no standard approach to evaluating the effect of analyst characteristics. We reproduce analyses from two early studies (Clement (1999) and Clement and Tse (2003)) and extend these analyses to a more recent sample period and across different methodological approaches and alternative analyst performance measures. We provide robust evidence that analyst experience is positively associated with earnings forecast accuracy but that associations for analyst resources and busyness are sensitive to variable measurement and fixed effect choices. Our results can inform accounting and finance scholars examining analyst performance as they consider which analyst characteristics to include and how to test the robustness of their findings.
Customer Satisfaction and Internal Control
Authors: Chen Ting , Liu Xiaotao Kelvin , Wan Chi , Wang Yakun 
Published: September 2023

ABSTRACT
We investigate whether firms’ ineffective internal control over financial reporting is associated with customer satisfaction, measured by product ratings on Amazon.com. Internal control weaknesses will likely corrupt the information environment, compromise coordination, and divert corporate resources to address the control deficiencies. Using a large sample of product rating data from Amazon.com, we find robust and consistent evidence that internal control weaknesses are negatively associated with customer satisfaction. Furthermore, the negative association is more pronounced for environment-level (versus other) internal control weaknesses, noncore (versus core) products, and more (versus less) operationally complex firms. Our findings provide initial evidence that ineffective internal control compromises customer satisfaction.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: M11; M41; M42; M48.
What Characterizes Nordic Research on Initial Teacher Education: A Systematic Scoping Review
Authors: Forsström Sanna , Munthe Elaine 
Published: September 2023

The main objective of this systematic scoping review is to shed light on ITE research in the Nordic countries during the past decade. The review includes 830 studies, following established procedures. Based on our analyses we find that Nordic ITE research is mainly on ITE for the compulsory and upper secondary school years. Researchers use qualitative data, view studies, and cross-sectional studies more than other methods and designs, and show more interest in STEM, pedagogy, and 21st century skills. A digital gap map accompanies this article and provides insight into future research needs.
Test the Optical and Structural Characteristics of Nano PbO Produced by Plasma–jet Technique
Authors: Aadim Kadhim A. , Gadaan Omar A. , Razyg K. H. 
Published: September 2023

The induced plasma technique was used in the current investigation to create lead oxide nanoparticles from bulk structures at various bombardment periods (4,6,8,10) min. The process will be carried out in the presence of argon gas that flows at a constant rate (3 L/sec). These nanoparticles were created as thin layers on various thicknesses of glass substrates prepared at different times of shelling”. After that, they were analyzed with an x-ray spectrum, scanning electron microscope (SEM), atomic force microscope (AFM) and UV-visible spectrophotometer. Where the optical characteristics and constants were examined, the energy gap of the films varied with bombardment periods from 2.1 ~1.98eV. The SEM and AFM images clearly display a structure that varies with bombardment duration due to the fluctuation in the diameter of the nanoparticles. Finally, the layers' entire amorphous nature is revealed by the x-ray spectrum.
Linguistic Means of Expressing Epistemic Modality in an English-language Scientific Text
Authors: Nurieva N. S. , Razheva E. S. 
Published: September 2023

Modality is a complex grammatical and functional-semantic category which is reflected in various types of discourse. The relevance of studying epistemic modality, reflecting the author’s knowledge of the reported information and his/her attitude to it from the point of view of its reliability, is determined by the necessity to analyze the linguistic features of its expression in a scientific text. The aim of the paper is to study morphological, lexical-syntactical and lexical means of expressing modality and to identify their pragmatic functions in English-language texts concerned with engineering. The study of the linguistic component in a scientific text will help foreign researchers present their scientific works in accordance with the authentic features of English. This determines the theoretical significance of studying the author’s means of expressing epistemic modality as a method for reasoning their scientific propositions, interacting with the target reader and expressing academic responsibility. The study of theoretical works by foreign and Russian scientists has shown that epistemic modality of a scientific text implements mainly the properties of the author’s subjective approach. However, unlike other types of discourse, the modality of a scientific text identifies a certain degree of objectivity in the author’s approach since it is characterized by the assessment of the reported information in terms of its reliability/unreliability. The given study assumes that the category of modality of any text, including a scientific one, is difficult to analyze statistically. It is known that the expression of the English text modality is characterized by imperceptible “transitions” between different levels of its implementation. Therefore, the paper considers some linguistic means at the morphological, lexical-syntactical and lexical levels. They include the verbal category of the imperative, subjunctive and presumptive types of mood, infinitive constructions, modal verbs and modal words of various parts of speech with the seme “expectation/assumption”. The article underlines an additional pragmatic aspect of modality means in an English-language scientific text concerned with the need for soft persuasion of the professional community to accept the information presented.
KOMPARASI INTERIOR RUMAH TRADISIONAL NUSANTARA: RUMAH JOGLO YOGYAKARTA INDONESIA DAN RUMAH MELAKA MALAYSIA
Authors: Anggriani Swastika Dhesti , - Ponimin , Sidyawati Lisa , Ujang Norsidah 
Published: September 2023

This study aims to determine the differences and similarities between traditional houses in Nusantara with research samples taken from 2 countries namely Joglo traditional hoise in Yogyakarta Indonesia and Melaka traditional house in Melaka Malaysia. The research method used is qualitative by means of descriptive research that takes the type of comparative activities of traditional house in Nusantara. Data obtained from direct observation to the location (Yogyakarta and Malaysia), interviews with informants, and taking documents data in the form of photos, layout drawings, and images. The results showed similarities and differences between the Joglo traditional house in Yogyakarta, Indonesia and the Melaka tarditional house in Malaysia. Judging from the aspect of the building, the Joglo house was built directly above ground level while the Melaka house was built with a stage system. The different types of buildings, plus the different users and spatial activities, lead to differences in interior layout. However, both Joglo traditional house and Melaka traditional house were built in 1 building mass. Both houses also still use wood material in some parts of the house. In addition, the house is also supported by poles that use wood material. Keyword: Comparation, Interior, Traditional House, Joglo, Melaka Penelitian ini bertujuan untuk mengetahui perbedaan dan persamaan diantara rumah tradisional Nusantara dengan sampel penelitian yang diambil dari 2 negara yaitu rumah tradisional Joglo Yogyakarta Indonesia dan rumah tradisional Melaka Malaysia. Metode penelitian yang digunakan adalah kualitatif dengan cara penelitian deskripsi yang mengambil jenis kegiatan komparasi rumah tinggal tradisional Nusantara. Data diperoleh dari observasi langsung ke lokasi (Yogyakarta dan Malaysia), wawancara kepada narasumber, serta mengambil data dalam bentuk dokumen berupa foto, gambar layout, dan gambar tampak. Hasil penelitian menunjukkan adanya persamaan dan perbedaan antara rumah Joglo Yogyakarta, Indonesia dan rumah Melaka Malaysia. Ditinjau dari aspek bangunan, rumah Joglo dibangun langsung di atas permukaan tanah sedangkan rumah Melaka dibangun dengan sistem panggung. Perbedaan jenis bangunan ini, ditambah perbedaan pengguna dan aktivitas ruangnya, menyebabkan adanya perbedaan tata ruang interior di dalamnya. Akan tetapi, Baik rumah Joglo dan Rumah Melaka dibangun dalam 1 massa bangunan. Kedua rumah tersebut juga masih menggunakan material kayu di beberapa bagian rumah. Selain itu, rumah juga disangga oleh tiang yang menggunakan material kayu. Keyword: Komparasi, Interior, Rumah Tradisional, Joglo, Melaka
Bimbingan dan konseling di pesantren berlandaskan nilai religiusitas: kajian teori dan pola dasar
Authors: Fachrurrazi Muhammad , Fitri Susi , Hidayat Dede Rahmat 
Published: September 2023

Perkembangan disiplin ilmu serta penerapan layanan program bimbingan dan konseling religius memiliki kesamaan konseptual dasar dengan karakter dan pola aplikatif di lembaga-lembaga pendidikan Islam berbasis pondok pesantren. Tujuan dari penelitian ini adalah untuk memberikan gambaran dan kerangka konseptual dasar mengenai penerapan layanan program bimbingan dan konseling di pesantren berlandaskan nilai-nilai religiusitas. Penelitian ini berbentuk penelitian kualitatif, dengan menggunaka pendekatan penelitian kepustakaan dan analisis isi sebagai teknik analisis data. Hasil yang diperoleh adalah terdapat lima landasan dasar (filosofis, psikologis, empiris, regulatif, sosial-budaya/pengalaman beragama) dan dua domain utama (pengasuhan dan pendidikan) dalam mengintegrasikan nilai-nilai religiusitas ke dalam layanan program bimbingan dan konseling di dalam lingkungan pesantren.