bluuebunny/crossref_metadata_2025_split huggingface dataset:
KdV breathers on a cnoidal wave background
Authors: Hoefer Mark A , Mucalica Ana , Pelinovsky Dmitry E 
Published: March 2023

Abstract
Using the Darboux transformation for the Korteweg–de Vries equation, we construct and analyze exact solutions describing the interaction of a solitary wave and a traveling cnoidal wave. Due to their unsteady, wavepacket-like character, these wave patterns are referred to as breathers. Both elevation (bright) and depression (dark) breather solutions are obtained. The nonlinear dispersion relations demonstrate that the bright (dark) breathers propagate faster (slower) than the background cnoidal wave. Two-soliton solutions are obtained in the limit of degeneration of the cnoidal wave. In the small amplitude regime, the dark breathers are accurately approximated by dark soliton solutions of the nonlinear Schrödinger equation. These results provide insight into recent experiments on soliton-dispersive shock wave interactions and soliton gases.
Development of a biomimetic arch-like 3D bioprinted construct for cartilage regeneration using gelatin methacryloyl and silk fibroin-gelatin bioinks
Authors: Chakraborty Juhi , Fernández-Pérez Julia , van Kampen Kenny A , Roy Subhadeep , ten Brink Tim , Mota Carlos , Ghosh Sourabh , Moroni Lorenzo 
Published: March 2023

Abstract
In recent years, engineering biomimetic cellular microenvironments have been a top priority for regenerative medicine. Collagen II, which is arranged in arches, forms the predominant fiber network in articular cartilage. Due to the shortage of suitable microfabrication techniques capable of producing 3D fibrous structures, in vitro replication of the arch-like cartilaginous tissue constitutes one of the major challenges. Hence, in the present study, we report a 3D bioprinting approach for fabricating arch-like constructs using two types of bioinks, gelatin methacryloyl (GelMa) and silk fibroin-gelatin (SF-G). The bioprinted SF-G constructs displayed increased proliferation of the encapsulated human bone marrow-derived mesenchymal stem cells compared to the GelMA constructs. Biochemical assays, gene, and protein expression exhibited the superior role of SF-G in forming the fibrous collagen network and chondrogenesis. Protein-protein interaction study using Metascape evaluated the function of the proteins involved. Further GeneMANIA and STRING analysis using Col 2A1, SOX 9, ACAN, and the genes upregulated on day 21 in RT-PCR, i.e. β-catenin, TGFβR1, Col 1A1 in SF-G and PRG4, Col 10A1, MMP 13 in GelMA validated our in vitro results. These findings emphasized the role of SF-G in regulating the Wnt/β-catenin and TGF-β signaling pathways. Hence, the 3D bioprinted arch-like constructs possess a substantial potential for cartilage regeneration.
Investigation of electron cyclotron wave absorption and current drive in CFETR hybrid scenario plasmas
Authors: WANG Hanlin , WANG Xiaojie , ZHANG Chao , TANG Yunying , LIU Fukun 
Published: March 2023

Abstract
The investigation of electron cyclotron (EC) wave absorption and current drive has been performed for the China Fusion Engineering Test Reactor (CFETR) hybrid scenarios using the TORAY code. To achieve the physics goal of the EC system in CFETR, a total of four wave frequency values and nine locations of launching antennas have been considered, and the injection poloidal and toroidal angles have been scanned systematically. The electron cyclotron current drive (ECCD) efficiency of the 170 GHz EC system is quite low due to the wave-particle interactions being located at the low-field side. To optimize the ECCD efficiency, the wave frequency is increased up to 221–250 GHz, which leads to the power being deposited at the high-field side. The off-axis ECCD efficiency can be significantly enhanced by launching EC waves from the top window and injecting them towards the high-field side. The optimized ECCD efficiency at ρ = 0.32 and at ρ = 0.4 is 2.9 and 2.2 times that of 170 GHz, respectively.
Musical Ontology and the Audibility of Musical Works
Authors: Gutiérrez Sofía Meléndez 
Published: March 2023

AbstractThere are compelling reasons to believe that musical works are abstract. However, this hypothesis conflicts with the platitude that musical works are appreciated by means of audition: the things that enter our ear canals and make our eardrums vibrate must be concrete, so how can musical works be listened to if they are abstract? This question constitutes the audibility problem. In this paper, I assess Julian Dodd’s elaborate attempt to solve it, and contend that Dodd’s attempt is unsuccessful. Then I discuss what I take to be the ideal response to the audibility problem, and show that it ultimately fails. I contend, consequently, that the project of construing musical works as audible is disheartening. Accordingly, in my last section, I will argue the audibility problem may be satisfactorily resolved without ascribing audibility to musical works.
Elevated troponin I is associated with a worse long-term prognosis in patients undergoing beating-heart coronary surgery
Authors: Kim Kang Min , Kim Sang Yoon , Jung Joon Chul , Chang Hyoung Woo , Lee Jae Hang , Kim Dong Jung , Kim Jun Sung , Lim Cheong , Park Kay-Hyun 
Published: March 2023

Abstract

OBJECTIVES
The impacts of elevated troponin I levels after coronary artery bypass grafting (CABG) on long-term outcomes were investigated.

METHODS
A total of 996 patients who underwent elective isolated CABG for stable or unstable angina were enrolled. Patients were divided into higher and lower groups based on 80th percentile postoperative peak troponin I (ppTnI) levels. The relationship between ppTnI and long-term clinical outcomes was analysed.

RESULTS
The median ppTnI was 1.55 (2.74) ng/ml and was significantly higher in the conventional CABG subgroup than in the beating-heart CABG subgroup: 4.04 (4.71) vs 1.24 (1.99) ng/ml, P &lt; 0.001. The 80th percentile of ppTnI was 3.3 ng/ml in the beating-heart CABG subgroup and 8.9 ng/ml in the conventional CABG subgroup. In the conventional CABG subgroup (n = 150), 10-year overall survival showed no significant difference between the higher (≥8.9 ng/ml) and lower (&lt;8.9 ng/ml) ppTnI groups: 71% (10%) vs 76% (5%), P = 0.316. However, the beating-heart CABG subgroup (n = 846) showed significantly worse 10-year overall survival in the higher ppTnI group (≥3.3 ng/ml) than in the lower ppTnI group (&lt;3.3 ng/ml): 64% (6%) vs 73% (3%), P = 0.010. In the beating-heart CABG subgroup, multivariable analysis showed that ppTnI exceeding the 80th percentile was a risk factor for overall death (hazard ratio: 1.505, 95% confidence interval: 1.019–2.225, P = 0.040).

CONCLUSIONS
Higher ppTnI over the 80th percentile was associated with worse long-term survival in beating-heart CABG, but not in conventional CABG.
Gene flow accelerates adaptation to a parasite
Authors: Lewis Jordan A , Kandala Prathyusha , Penley McKenna J , Morran Levi T 
Published: March 2023

Abstract
Gene flow into populations can increase additive genetic variation and introduce novel beneficial alleles, thus facilitating adaptation. However, gene flow may also impede adaptation by disrupting beneficial genotypes, introducing deleterious alleles, or creating novel dominant negative interactions. While theory and fieldwork have provided insight into the effects of gene flow, direct experimental tests are rare. Here, we evaluated the effects of gene flow on adaptation in the nematode Caenorhabditis elegans during exposure to the bacterial parasite, Serratia marcescens. We evolved hosts against nonevolving parasites for 10 passages while controlling host gene flow and source population. We used source nematode populations with three different genetic backgrounds (one similar to the sink population and two different) and two evolutionary histories (previously adapted to S. marcescens or naive). We found that populations with gene flow exhibited greater increases in parasite resistance than those without gene flow. Additionally, gene flow from adapted populations resulted in greater increases in resistance than gene flow from naive populations, particularly with gene flow from novel genetic backgrounds. Overall, this work demonstrates that gene flow can facilitate adaptation and suggests that the genetic architecture and evolutionary history of source populations can alter the sink population’s response to selection.
Heat and mass transfer in different concrete structures: a study of self-compacting concrete and geopolymer concrete
Authors: Ebid Ahmed M , Onyelowe Kennedy C , Kontoni Denise-Penelope N , Gallardo Alberto Quintana , Hanandeh Shadi 
Published: March 2023

AbstractThermal characteristics of concrete are one of the main topics in concrete technology researches. They were extensively studied since the 1980s to predict the behavior of the concrete in fire and the performance of massive concrete. However, this topic was raised again after 2010 as a part of sustainable, energy effective and ecofriendly buildings studies. The aim of this research is to present a comparison between the thermal characteristics of self-compacted concrete (SCC) and the geopolymer concrete (GPC) using collected previous researches. More than fifty references were collected, sorted and analyzed in the last forty years. The results showed that (GPC) has better thermal characteristics, such as thermal conductivity, heat capacity, fire resistance, while (SCC) has better mechanical properties, such as compressive strength, early strength and elastic modulus. Besides that, from ecological point of view, partially replacing of ordinary Portland cement (OPC) with microencapsulated phase change materials (MPCM), such as fly ash, silica fume, slag and metakaolin, remarkably decreases the CO2 footprint of construction industry.
Thermal optimization research of vertical tube climbing film desalination system
Authors: Yang Yong , Ren Xiaotong , Li Yiqiao , Yuan Dayuan , Guo Yali , Zhang Kun , Shen Shengqiang 
Published: March 2023

Abstract
Based on the pinch theory and energy cascade utilization principle, the performance of a multi-effect shipboard vertical tube climbing film desalination system combined thermal vapor compression with different preheating configuration has been analyzed. The mathematical model is established for thermodynamic simulation, in which various thermodynamic losses caused by boiling point elevation and pressure drop are considered, and the effective heat transfer temperature difference and the hot side temperature difference are used to analyze the influences of heating steam temperature, final effect evaporation temperature, and concentration ratio on thermal performance including gained output ratio (GOR)—specific heat transfer area for different preheating configuration. The results show that the internal average effective heat transfer temperature difference determines characteristics of multi-effect distillation (MED) system. While for system with similar average effective heat transfer temperature, the temperature difference of hot side is the controlling parameter. And the energy cascade utilization principle shows the controlling attribute in MED thermodynamic system, as GOR is improved mainly due to utilization of the secondary energy and residual energy of the heating steam for preheating process.
Morphometric and sexual characteristics ofMacrobrachium rosenbergii(De Man, 1879) from the Nyatoh River, Malaysia
Authors: Okomoda Victor Tosin , Hon Jung Liew , Suhairi Mazelan , Mohd Sabri Muda , Zaidi Ibrahim , Iffa Rezuan Rusdi , Rohisyamuddin Othman , Nurul Hayati Ismail , Gusti Afis Gusti Roslan , Sairatul Dahlianis Ishak , Ahmad Najmi Ishak , Nor Azman Kasan , Liqun Liang , Yumei Chang , Ikhwanuddin Mhd Abdullah 
Published: March 2023

AbstractThis study was conducted to evaluate the morphological variation of Macrobrachium rosenbergii (De Man, 1879) from the Nyatoh River, Terengganu state, Malaysia. Three hundred and thirty-five samples of M. rosenbergii comprising 41.5% males and 58.5% females were collected from August 2019 to October 2020. The bulk of the sample collection had small claws (69.1%), whereas those with orange and blue claws constituted 19.1% and 11.8%, respectively. The result obtained from the analysis of nine sets of morphometric data for both sexes showed univariate morphometric similarities and wide overlap in principal component analysis (PCA) without separation into unique clusters. Comparison by claw-type showed significant variation in the univariate analysis of the morphometric parameters measured in the following order: blue claw &gt; orange claw &gt; small claw. PCA did not cluster the prawns into different groups, hence multivariate analysis of morphometric parameters cannot be used to distinguish the prawn by claw type should the appendages be lost. Comparisons of the length-weight relationship data and condition factor suggest that the Terengganu River prawn population had a positive allometric growth pattern and were in good condition. The Pearson’s correlation analysis also showed a largely positive relationship between the morphometric data collected (with a few exceptions in the different morphotypes). The morphological measurements could not therefore be used to discriminate the sex and claw-type of freshwater prawn M. rosenbergii in the Nyatoh River.
Interactive Digital Platforms, Human Rights Fact Production, and the International Criminal Court
Authors: MacLean Ken 
Published: March 2023

Abstract
The International Criminal Court (ICC) initiated criminal proceedings against Ahmad Al Faqi Mahdi in 2016 for the war crime of directing the destruction of religious monuments in Timbuktu, Mali, in the context of a non-international conflict. The monuments included nine mausoleums of Sufi saints that Islamist groups regarded as idolatrous, one mosque, and approximately four thousand ancient manuscripts. The case, which successfully ended in a guilty plea, marks the first time that the ICC charged an individual with a ‘cultural heritage’ crime. The prosecution’s argument during the hearing relied heavily on an interactive digital platform that facilitated the organization, analysis, and presentation of the evidence to the court. SITU, an applied research organization, created the platform in collaboration with the ICC’s Office of the Prosecutor. It combined geospatial information, historic satellite imagery, photographs, open-source videos, and other types of site documentation to help the ICC judges visualize what was no longer physically there. The result was a digital reconstruction featuring structures and their contents lost to explosives, pickaxes, and hammers. The theoretical, methodological, and ethical issues that arose out of the collaboration, the focus of this article, highlights the multiple ways in which such platforms fashion ‘facts’ rather than objectively present them. A close analysis of the design decisions made, visualization techniques employed, and presentation strategies used to support the case against the defendant highlights both the possibilities and limits of such platforms as part of future international criminal proceedings.
Cardiac impacts of postoperative radiotherapy for breast cancer in Japanese patients
Authors: Segawa Erika , Jingu Keiichi , Umezawa Rei , Yamamoto Takaya , Takahashi Noriyoshi , Kadoya Noriyuki , Takeda Ken 
Published: March 2023

Abstract
Radiotherapy for breast cancer has attracted attention in Western countries because radiation to the heart can cause cardiac events. The purposes of this study were to evaluate the relationship between radiotherapy after breast-conserving surgery and the frequency of cardiac events in Japanese patients and to investigate the risk factors of cardiac events after postoperative radiotherapy in those patients. Female patients who received postoperative radiotherapy following breast-conserving surgery between 2007 and 2012 at our hospital were evaluated. In this study, we estimated the cumulative incidence of cardiac events including angina pectoris, myocardial infarction, ischemic heart disease, heart failure and cardiomyopathy after radiotherapy. Of 311 eligible patients, 7.1% of the patients had a smoking history, 20.3% of the patients were obese and 22.2% of the patients had hypertension. The median follow-up period was 118 months (interquartile range, 102–132 months). Twelve patients (3.9%) experienced cardiac events after treatment. The mean time to cardiac events was 126 months. The 10-year cumulative incidences of cardiac events after treatment were 4.2% and 4.3% for patients with left-sided and right-sided breast cancer, respectively, without a significant difference. Multivariate analysis showed that only hypertension was a risk factor for cardiac events (hazard ratio = 16.67, P = 0.0003). In conclusion, postoperative radiotherapy for breast cancer did not increase the incidence of cardiac events. Since at least 2007, postoperative radiotherapy for breast cancer has been safely performed without effects on the heart.
Assessing the reporting quality of adult neuro-oncology protocols, abstracts, and trials: Adherence to the SPIRIT and CONSORT statements
Authors: Suppree Joshua S , Patel Avni , Keshwara Sumirat M , Krishna Sandhya Trichinopoly , Gillespie Conor S , Richardson George E , Mustafa Mohammad A , Hart Sophia , Islim Abdurrahman I , Jenkinson Michael D , Millward Christopher P 
Published: March 2023

Abstract

Background
Comprehensive and transparent reporting of clinical trial activity is important. The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 and Consolidated Standards of Reporting Trials (CONSORT) 2010 statements define the items to be reported in clinical trial protocols and randomized controlled trials, respectively. The aim of this methodological review was to assess the reporting quality of adult neuro-oncology trial protocols and trial result articles.

Methods
Adult primary and secondary brain tumor phase 3 trial protocols and result articles published after the introduction of the SPIRIT 2013 statement, were identified through searches of 4 electronic bibliographic databases. Following extraction of baseline demographic data, the reporting quality of independently included trial protocols and result articles was assessed against the SPIRIT and CONSORT statements respectively. The CONSORT-A checklist, an extension of the CONSORT 2010 statement, was used to specifically assess the abstract accompanying the trial results article. Percentage adherence (standard deviation [SD]) was calculated for each article.

Results
Seven trial protocols, and 36 trial result articles were included. Mean adherence of trial protocols to the SPIRIT statement was 79.4% (SD: 0.11). Mean adherence of trial abstracts to CONSORT-A was 75.3% (SD: 0.12) and trial result articles to CONSORT was 74.5% (SD: 0.10).

Conclusion
The reporting quality of adult neuro-oncology trial protocols and trial result articles requires improvement to ensure comprehensive and transparent communication of planned neuro-oncology clinical trials and results within the literature. Raising awareness by clinical triallists and implementing mandatory evidence of proof of adherence by journals should improve reporting quality.
Failure of Early Mycological Clearance in HIV-Negative Cryptococcal Meningitis
Authors: Su Zhihui , Luo Chongliang , Dai Kai , Yuan Dasen , Qin Bang-e , Gu Meifeng , Liu Junyu , Chen Yong , Peng Fuhua , Jiang Ying 
Published: March 2023

AbstractBackgroundNegative cerebrospinal fluid (CSF) cultures at 2 weeks after antifungal treatment (early mycological clearance [EMC]) should be a treatment goal of cryptococcal meningitis (CM). However, EMC in human immunodeficiency virus (HIV)–negative patients with CM is poorly understood.MethodsWe conducted a retrospective review of medical records and 1-year follow-up of 141 HIV-negative patients with CM with an initial positive CSF culture for Cryptococcus neoformans. Multivariate logistic regression was performed to analyze clinical features and laboratory and CSF findings of patients with CM with different EMC statuses. Random forest models were used to predict failure of EMC. All-cause mortality and clinical functional status were analyzed.ResultsOf 141 patients, 28 (19.9%) had EMC failure. The 1-year mortality rate was 5.7% (8/141). Multivariate analysis showed that non–amphotericin B (AmB)–based regimens, baseline log10Cryptococcus count/mL, baseline CSF opening pressure (CSF-OP) &gt;30 cm H2O, and baseline serum creatinine were significantly associated with EMC failure. A parsimonious predictive rule given by the decision tree identified patients with CM with non-AmB-based therapy and baseline CSF-OP &gt;30 cm H2O as being at high risk of EMC failure. Incidence of all-cause mortality, the follow-up modiﬁed Rankin Scale, and Karnofsky performance status scores were not significantly related to EMC.ConclusionsEMC failure in HIV-negative CM is attributed to non-AmB-based therapy and is associated with log10Cryptococcus count/mL and CSF-OP &gt;30 cm H2O at baseline. Because of the small number of deaths, we are not able to comment on whether or not EMC is associated with mortality.
The Nature of Light
Authors: Katsos Isidoros C. 
Published: March 2023

Abstract
This chapter reconstructs a hexaemeral theory of light from a combined reading of the sources. Through the causal interlink of fire and light, hexaemeral light is theorized as the purest kind of fire. The chapter explores the language and physical properties of fire that explain luminosity: the light ray, its liminal corporeality, its radiancy and causticity, its propagation in space, its velocity, and its interaction with the medium. The investigation proceeds on to the nature of light itself and the relation of its causal principle to its effects. Sensible and intelligible light are logically and hermeneutically distinguished even though they remain ontologically and hermeneutically interlinked. Hexaemeral exegesis, if successfully performed, enables the reader to emerge from the sensible experience of light to the intelligible grasp of its formative logos.
Conclusions
Authors: Katsos Isidoros C. 
Published: March 2023

Abstract
The concluding chapter gathers together the various stages of the argument of the study. It gives a clear answer to the research question ‘what is light?’ and offers a synthetic disambiguation of the multiple uses of light language in the sources. The reflective interplay between physics, metaphysics, and light language unfolds the full anagogical potential of the hexaemeral narrative as spiritual exercise, transposing the biblical text from the level of cosmogonical literary narrative to the level of contemplative introspection of the self. The light/mind analogy becomes the apex of hexaemeral exegesis, capturing paradigmatically the embodied, trinitarian, and Christocentric hylomorphism of the Christian metaphysics of creation. It thus serves as the ground of meaning of the early Christian language of light.
Personality Assessment in Neuropsychological Settings
Authors: Dumitrascu Nicolae R. 
Published: March 2023

Abstract
This chapter discusses the importance of personality assessment in neuropsychological settings (e.g., to establish the contribution of psychopathology to symptom presentation). The Hierarchical Taxonomy of Psychopathology (HiTOP) transdiagnostic and dimensional model of psychopathology is emerging as a helpful paradigm guiding the practice of personality assessment with neuropsychiatric patients. The chapter discusses (a) the roles of personality assessment in the neuropsychology clinic; (b) potential implications of the HiTOP model of conceptualizing psychopathology on conducting personality assessment as part of neuropsychological assessment; (c) the advantages of using a multimethod approach in assessment (e.g., self-report and implicit personality measures; maximal and typical performance measures); (d) the research with the Personality Assessment Inventory clinical scales in acquired brain injuries; and (e) research with the Rorschach Inkblot Test in assessing alexithymia in patients with chronic pain and psychosis.