bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using STEAM and Bio-Inspired Design to Teach the Entrepreneurial Mindset to Engineers
Authors: Bosman Lisa , Shirey Katherine L. 
Published: July 2023

AbstractThe need for addressing global and societal problems is stronger than ever, as demonstrated by the UN Sustainable Development Goals and National Academy of Engineering Grand Challenges. However, engineering undergraduate students rarely get to experience engaging with the associated real-world projects and challenges. This has the potential to result in attenuation from engineering education and career pathways. This study aimed to overcome this issue by reaching the United States’ untapped future engineering workforce via an engineering educator professional development “train-the-trainer” program. This train-the-trainer program guided engineering educators to apply evidence-based pedagogical methods (e.g., backward course design) to couple entrepreneurial mindset (EM) development with STEAM (science, technology, engineering, arts, math) and bio-inspired design in an effort to improve the retention of underrepresented engineering students via a transdisciplinary, humanistic approach. This study employed a mixed methods approach including retrospective post-then-pre items based on perceived learning gains, rating the overall satisfaction with the program, and open-ended questions to better understand what went well, what did not go so well, and what can be improved. From a practical perspective, this study shows that integrating STEAM (with a specific focus on the arts) into the engineering classroom promotes problem-solving and critical thinking across disciplines. Here, applying STEAM principles encourages diverse perspective taking and making by bridging paradigms and theoretical frameworks across a variety of humanities and technical disciplines. As a result, combining STEAM with bio-inspired design and the EM has the capacity to increase engagement and broaden participation among students traditionally underrepresented in engineering, including females and minoritized populations.
Mnemonic ‘Boundary Objects’ and Postcolonial Restitution
Authors: Zolkos Magdalena 
Published: July 2023

AbstractDrawing on new materialist and object-centered historical criticism, this article analyses colonial and post-colonial discourses of the Greenlandic figurines of the mythical being of ill-wishing and revenge, tupilak (plural form: tupilait). It focuses on three tupilak figures, made in 1905/1906 by a shaman Mitsivarniannga on a request of a Danish ethnographer William Thalbitzer, which today are part of the Danish National Museum collections. In the early 20th century, Greenlandic tupilait (and Inuit cultural production in general) were an object of fascination among European collectors, artists, and the general public. Asking what these objects had come to mean in (and for) Europe, this article points to marginalized Greenlandic narratives of Mitsivarniannga’s tupilat, and builds a critical narrative of these objects as material effects of the disruptions of indigenous community and sustenance by Western colonialism. Drawing on critical insights from the current post-colonial restitution debates, it problematizes the differential political-economic conditions and relations of power, under which the colonial acquisitions and procurements took place. The article argues that cultural heritage items, such as the three tupilat, are mnemonic ‘boundary objects’ that can potentially forge links between disparate memories of colonialism in Denmark and Greenland.
How I live [participate] now: Re-negotiating social belonging and linguistic participation in book-group discussions
Authors: Granqvist Angelica 
Published: July 2023

Abstract
This paper focuses on how Gabriella, an upper-secondary student in Sweden, re-negotiated social belonging and linguistic participation in book-group discussions involving students in the school subjects Swedish and Swedish as a second language. Gabriella immigrated to Sweden due to forced migration. As a Swedish language learner, she worried that her language proficiency was regarded as insufficient by her peers. Within the frame of linguistic ethnography, and with the aim of identifying Gabriella’s trajectory of participation in book-group discussions over time, audio-recorded group discussions about the novel How I live now, interview data, and observational fieldnotes were analyzed by means of an epistemic stance analysis. Building on learning as participation, it was possible to unfold how Gabriella went from a passing participant to a driving force. Her trajectory of participation was spurred by the content of the novel and a sense of epistemic responsibility to share her first-hand experience of war, while her classmates responded with silence. From an educational perspective, this paper emphasizes the importance of classrooms as contact zones where students are not only provided with rich opportunities to gather around literature that stirs up questions of what it means to be human, but more importantly, it accentuates the need for literary education to include responsive practices to help students accommodate each other as co-learners.
A novel approach to enhancing the Klobuchar algorithm to mitigate the effect of ionospheric delay errors on static single-frequency receivers
Authors: Elshambaky Hossam Talaat 
Published: July 2023

Abstract
The demand for real-time high-precision positioning for global navigation satellite system applications is difficult to satisfy. In this regard, a single-frequency receiver is found to play an important role in overcoming this challenge, especially in developing countries where economic factors are a major restriction. Hence, the development of built-in models, such as the Klobuchar model, is an important objective for single-frequency users to mitigate the effect of ionospheric delay errors in real-time applications. Accordingly, this study aims to devise a new approach to enhance the behavior of the Klobuchar model and increase its efficiency in resolving the aforementioned problem. The new approach seeks to enhance the behavior of the Klobuchar model without refining or increasing its coefficients. To eliminate the ionospheric delay disturbance, the proposed methodology applies normalization and filtration processes to the raw ionospheric delay probability distribution estimated by the unified least squares technique. A final assessment of the new method for enhancing the Klobuchar behavior in predicting the precise position of a single-frequency static receiver under different weather conditions around the globe is presented in this paper.
Crushing performance and optimization of bio-inspired multi-cell columns
Authors: Öztürk İsmail 
Published: July 2023

Abstract
Multi-cell columns inspired by diatom algae have been examined regarding crashworthiness. Crushing simulations have been conducted for AA2024-T351, B1500HS-O25, and a combination of these materials. The highest specific energy absorption and lowest peak crushing force value were obtained with a homogenous AA2024-T351 column. Single and multi-objective optimization studies have been conducted with this column to find the best design. This design could be used in crash-box-like structures in automotive design.
A multi-strategy boosted prairie dog optimization algorithm for global optimization of heat exchangers
Authors: Gürses Dildar , Mehta Pranav , Sait Sadiq M. , Kumar Sumit , Yildiz Ali Riza 
Published: July 2023

Abstract
In this article, a new prairie dog optimization algorithm (PDOA) is analyzed to realize the optimum economic design of three well-known heat exchangers. These heat exchangers found numerous applications in industries and are an imperative part of entire thermal systems. Optimization of these heat exchangers includes knowledge of thermo-hydraulic designs, design parameters and critical constraints. Moreover, the cost factor is always a challenging task to optimize. Accordingly, total cost optimization, including initial and maintenance, has been achieved using multi strategy enhanced PDOA combining PDOA with Gaussian mutation and chaotic local search (MSPDOA). Shell and tube, fin-tube and plate-fin heat exchangers are a special class of heat exchangers that are utilized in many thermal heat recovery applications. Furthermore, numerical evidences are accomplished to confirm the prominence of the MSPDOA in terms of the statistical results. The obtained results were also compared with the algorithms in the literature. The comparison revealed the best performance of the MSPDOA compared to the rest of the algorithm. The article further suggests the adaptability of MSPDOA for various real-world engineering optimization cases.
BCL2L13 protein prevents apoptosis in acute myeloid leukemia cells
Authors: Kim Ju-Heon , Kim Hyeng-Soo , Lee Sanggyu 
Published: July 2023

Abstract

Objectives
The B cell lymphoma-2 (BCL-2) protein group is essential for regulating apoptosis. BCL2L13 harbors all BH domains present in the BCL-2 protein family in addition to a BHNo domain comprising 250 amino acids at its C-terminal. BCL2L13 is highly expressed in AML and is involved in apoptosis. We investigated the possibility of discovering BCL2L13 as a treatment target for acute leukemia.

Methods
We reduced the expression of BCL2L13 in Mono Mac 6 (MM6) cells using shRNA and overexpressed BCL2L13 in THP-1 cells. MM6 and THP-1 cells were treated with staurosporine (STS) to confirm the role of BCL2L13 in apoptosis.

Results
In acute myeloid leukemia (AML) cells, BCL2L13 is involved in inhibiting apoptosis as evidenced by its strikingly augmented expression in these cells. BCL-2 was downregulated and cleaved Caspase 3, and sphingosine-1-phosphate phosphatase 1 (SGPP1) was upregulated when MM6 cells with knockdown BCL2L13 were treated with STS, which significantly increased their apoptosis. Furthermore, mitochondrial membrane potential decreased in MM6 cells in response to the downregulation of BCL2L13. In BCL2L13-depleted MM6 cells, the amount of cytochrome c increased in the cytoplasm. The THP-1 cells overexpressing BCL2L13 and treated with STS showed a significant decrease in the expression of genes related to apoptosis induction, resulting in decreased apoptosis.

Conclusion
BCL2L13 inhibits apoptosis in AML, and BCL2L13-specific inhibition might serve as a new strategy for treating this condition.
Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
Authors: Monteiro Pedro , Yeon Bongwhan , Wallis Samuel S , Godinho Susana A 
Published: July 2023

AbstractIntracellular organelle organization is conserved in eukaryotic cells and is primarily achieved through active transport by motor proteins along the microtubule cytoskeleton. Microtubule post‐translational modifications (PTMs) can contribute to microtubule diversity and differentially regulate motor‐mediated transport. Here, we show that centrosome amplification, commonly observed in cancer and shown to promote aneuploidy and invasion, induces a global change in organelle positioning towards the cell periphery and facilitates nuclear migration through confined spaces. This reorganization requires kinesin‐1 and is analogous to the loss of dynein. Cells with amplified centrosomes display increased levels of acetylated tubulin, a PTM that could enhance kinesin‐1‐mediated transport. Depletion of α‐tubulin acetyltransferase 1 (αTAT1) to block tubulin acetylation rescues the displacement of centrosomes, mitochondria, and vimentin but not Golgi or endosomes. Analyses of the distribution of total and acetylated microtubules indicate that the polarized distribution of modified microtubules, rather than levels alone, plays an important role in the positioning of specific organelles, such as the centrosome. We propose that increased tubulin acetylation differentially impacts kinesin‐1‐mediated organelle displacement to regulate intracellular organization.
Barroco, hoy: propuesta didáctica de enseñanza literaria en el aula del siglo XXI
Authors: Ramos Agudo Francisco 
Published: July 2023

En pleno siglo XXI, es necesario que los profesores de literatura reflexionemos sobre el adecuado planteamiento de aquello que queremos transmitir, más allá de exponer una serie de contenidos en sesiones magistrales. El presente artículo plantea, desde los postulados de la educación literaria y el protagonismo que esta confiere al alumno como lector activo que construye sus propios significados, un acercamiento didáctico al Barroco mediante una selección de tópicos y textos literarios que entroncan con la experiencia cultural de los estudiantes, buscando resucitar a los clásicos del siglo XVII en la más inmediata actualidad.Palabras clave: Barroco, educación literaria, didáctica, lectura, competencia
Rosa Chacel: entre circunstancias y voluntad
Authors: Trapanese Elena 
Published: July 2023

En el primer prólogo a su obra Estación. Ida y vuelta, la escritora española Rosa Chacel confiesa haber merecido, entre sus amigos íntimos, el título de “trabajador sin materias”, debido a que su fuente de escritura era lo ausente, lo distante, lo falto. Lejos de tratarse de fantasías, Chacel apunta lo que, para ella, constituye el carácter fundamental de la escritura: las circunstancias y la recreación voluntaria que de ellas ofrece la memoria. A partir de un estudio sobre la influencia de José Ortega y Gasset, este ensayo tiene el propósito de analizar las aportaciones de Chacel en relación con la escritura y con la voluntad, haciendo hincapié en las visiones del exilio y de la mujer que de ellas se desprendenPalabras clave: Rosa Chacel, voluntad, mujer, exilio
Etopeyas en Los pasos perdidos: la dialéctica entre música y literatura para la conformación carpenteriana de los personajes
Authors: Abellán Chuecos Isabel 
Published: July 2023

Si, como ya sabemos, música y literatura son indispensables en la vida de Alejo Carpentier, también a través de sus novelas veremos esta relación. En este estudio se pretende demostrar la importancia de ambas disciplinas para la conformación de las etopeyas e identidades de los personajes de Los pasos perdidos. Alejo Carpentier utilizará las grandes obras de la Literatura Universal así como de la Historia de la Música para dar sentido a la vida mundana de los protagonistas, usándolas en las acciones cotidianas de éstos al mismo tiempo que para realizarlos y conformarlos en su naturaleza, otorgando en sus vidas –a modo de vidas paralelas– relaciones con los prestigiosos personajes de sobra conocidos por todos como Ulises, don Quijote, Penélope o Ruth.Palabras clave: Alejo Carpentier, literatura, música, etopeyas
La obra dramática de Germán Rozenmacher: tradición y enfrentamiento. El mundo judío frente a la sociedad argentina
Authors: Saura Clares Alba 
Published: July 2023

En este estudio, buscamos introducirnos en la producción dramática del escritor argentino Germán Rozenmacher (1936-1971), a partir de sus textos primordiales, Réquiem para un viernes a la noche (1964) y Simón Brumelstein, el caballero de Indias (1970). En torno a estas obras, analizaremos el conflicto migratorio de la colectividad judía en Argentina, su contexto histórico-circunstancial (en relación al movimiento peronista) y el diálogo de sus textos con el desarrollo teatral contemporáneo. Se trata de una poética dramática realista, con la que Rozenmacher realiza un excelente retrato del individuo y de la sociedad judía en Argentina en el siglo XX.Palabras clave: Argentina, Judaísmo, Migración, Germán Rozenmacher
La gran novela del siglo XVIII: Eusebio. Influencias de Rousseau y Cervantes
Authors: Sauce Martín Víctor 
Published: July 2023

Este artículo intenta explicar de manera concisa las diferencias que hay entre el Eusebio de Montengón y el Emilio de Rousseau así como la distinción de género entre ambas y el distinto modelo de educación que tiene cada obra pues el aprendizaje de cada alumno es diferente, sobre todo debido al influjo de la tradición jesuita de Montengón. Además, se intenta analizar otras influencias recibidas, como la de Cervantes, a la hora de componer el Eusebio.Palabras clave: novela de aprendizaje, educación jesuita, didactismo, actividad pedagógica.
Variation in Inhaled Medication Use for Infants With Congenital Heart Disease and Bronchiolitis
Authors: Ahuja Namrata , Richardson Troy , Brady Patrick , Foster Byron A. , Godown Justin , Lu Elise , Madsen Nicolas , Shah Samir S. , Wagner Tamara , Wu Susan , Russell Christopher ,   for the Pediatric Research in Inpatient Settings (PRIS) Network
Published: July 2023

BACKGROUND AND OBJECTIVES
Current viral bronchiolitis guidelines exclude infants with congenital heart disease (CHD). Variations in the use of common therapeutics in this population and their associations with clinical outcomes are unknown. Our objective was to evaluate variations in (1) the use of β-2-agonists and hypertonic saline across hospitals among infants with CHD hospitalized with bronchiolitis, and (2) hospital-level associations between medication use and outcomes.

METHODS
We performed a multicenter retrospective cohort study using administrative data from 52 hospitals in the Pediatric Health Information System. We included infants ≤12 months old hospitalized from January 1, 2015 to June 30, 2019 for bronchiolitis with a secondary diagnosis of CHD. Primary exposures were the hospital-level proportion of days that patients received β-2-agonists or hypertonic saline. Linear regression models assessed the association between the primary exposure and length of stay, 7-day readmission, mechanical ventilation use, and ICU utilization, adjusting for patient covariates and accounting for clustering by center.

RESULTS
We identified 6846 index hospitalizations for bronchiolitis in infants with CHD. Overall, 43% received a β-2-agonist, and 23% received hypertonic saline. The proportion of days with the use of β-2-agonists (3.6% to 57.4%) and hypertonic saline (0.0% to 65.8%) varied widely across hospitals in our adjusted model. For both exposures, adjusted models revealed no association between days of use and patient outcomes.

CONCLUSIONS
For children with CHD hospitalized with bronchiolitis, hospital-level use of β-2-agonists and hypertonic saline varied widely, and their use was not associated with clinical outcomes.
Determining loading patterns in the bearing structure of a railroad flatcar with a floor made from sandwich panels
Authors: Lovska Alyona , Nerubatskyi Volodymyr , Okorokov Andrii , Vernyhora Roman , Zhuravel Iryna 
Published: July 2023

The object of research is the processes of emergence, perception, and redistribution of loads in the supporting structure of a flatcar with a floor made of sandwich panels.
To reduce the impact of dynamic loads on the supporting structure of a flatcar, as well as the safety of goods transported in it, it is proposed to manufacture floors from sandwich panels.
Within the framework of the study, mathematical modeling of the dynamic load on a flatcar when it runs in a loaded state was carried out. It was found that, taking into account the proposed solution, the accelerations acting on the supporting structure of a flatcar are reduced by 8.4 % compared to the typical one. At the same time, accelerations acting on cargo placed on a flatbed car are reduced by 11.7 %. The results of calculating the strength of sandwich panels, when arranged on a flatcar, proved the feasibility of the proposed improvement. The main indicators of dynamics of the improved flatcar structure operated in an empty state were determined. It was established that the flatcar movement is assessed as "good".
A feature of the results reported here is that the improved supporting structure of a flatcar contributes not only to reducing its dynamic load but also to improving the safety of transported cargoes.
The scope of practical application of the results is the engineering industry, in particular, railroad transport. The condition for the practical application of the research results is the use of energy-absorbing material in the structure of sandwich panels.
The study could contribute to devising recommendations regarding the design of modern structures of railroad vehicles and increasing the efficiency of the functioning of the transportation industry
Development of a method for the search of solutions in the sphere of national security using bio-inspired algorithms
Authors: Koval Volodymyr , Shyshatskyi Andrii , Ransevych Ruslan , Gura Viktoriya , Nalapko Oleksii , Shypilova Larysa , Protas Nadiia , Volkov Oleksandr , Stanovskyi Oleksandr , Chaikovska Olena 
Published: July 2023

The object of research are decision support systems. The subject of research is the decision-making process in management problems using bio-inspired algorithms.
A method for the search of solutions in the field of national security using bio-inspired algorithms is proposed. The proposed method is based on a combination of an artificial bat algorithm and evolving artificial neural networks. The method has the following sequence of actions:
‒ input of initial data;
‒ processing of initial data taking into account the degree of uncertainty;
‒ numbering of bat agents (BA);
‒ placement of bat agents taking into account the degree of uncertainty about the state of the analysis object in the search space;
‒ setting the initial BA speed and the echolocation frequency of each BA;
‒ starting a local search;
‒ launching a global search;
‒ training knowledge bases of bat agents.
The originality of the proposed method consists in the arrangement of bat agents taking into account the uncertainty of initial data, improved global and local search procedures taking into account the noise degree of data about the state of the analysis object.
Another feature of the proposed method is the use of an improved procedure for training bat agents. The training procedure consists in learning the synaptic weights of an artificial neural network, the type and parameters of the membership function, the architecture of individual elements and the architecture of the artificial neural network as a whole. The method makes it possible to increase the efficiency of data processing at the level of 13–21 % due to the use of additional improved procedures. The proposed method should be used to solve the problems of evaluating complex and dynamic processes in the interests of solving national security problems