bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creation of an Assessment Scale for Risk Factors of Intraoperative Pressure Injury in Pediatrics Using Delphi Method
Authors: Fang Zhihao , Chen Tian , Chen Qiuyu , Lin Zhixiong , Zhuo Qing , Ji Bin 
Published: September 2023

Abstract
Objective
To create a pressure Injury risk factor assessment form specifically designed for pediatric patients in the operating room, thus providing healthcare professionals with a scientific and effective nursing assessment tool to accurately and promptly assess the risk of stress injury in children undergoing surgery.
Methods
In this study, we conducted a comprehensive literature search and held group meetings to gather relevant evidence on the prevention of intraoperative stress injuries. We also obtained valuable opinions from the group meetings, to develop an initial pool of entries for the assessment form. To refine and enhance the assessment form, we employed the 2-round Delphi method. This involved sending two rounds of email inquiries to a panel of 22 experts, who provided valuable feedback and suggestions for modification. Finally, we analyzed the data obtained from the assessment form using statistical tests to derive meaningful insights and draw conclusions.
Results
The positive coefficients of the two rounds of expert consultation were 83.3% and 90.9%, respectively. The Cronbach's alpha coefficients were 0.913 and 0.915, respectively, indicating a high level of internal consistency. The Kendall's W coefficients were 0.400 and 0.124, respectively, suggesting a moderate level of agreement among the experts. After two rounds of correspondence, an evaluation table consisting of 3 first-level indicators and 11 second-level indicators was ultimately generated.
Conclusion
The assessment table demonstrates a strong positive coefficient and expert authority, indicating the reliability and validity of the form. These findings emphasize the necessity, feasibility, and reliability of constructing an assessment table for risk factors associated with intraoperative pressure injuries in pediatric patients.
Trial registration:
Not applicable. The study content is only used as an assessment modality and does not involve any medical intervention for the patients.
Diagnostic Utility of Perfusion Index in Identifying Radial Artery Embolism during Hyperthermic Intraperitoneal Chemotherapy Procedure: A Case Report
Authors: Eraslan İrem , Sarıoğlan Burak Taha , Ünsal Sinan , Kayhan Gülay Erdoğan 
Published: September 2023

Abstract
Invasive arterial cannulation is a widely used method in intensive care units and operating rooms. However it has potential complications such as thrombosis, peripheral embolism, hematoma formation, and infection. The Masimo Root Radical-7 Pulse CO-Oximeter® (Masimo Corporation, Irvine, CA, USA) is a non-invasive hemodynamic monitoring device that measures perfusion index and pleth variability index, provides guidance to anaesthesiologists in the cases where hemodynamic fluctuations are expected. In this particular case, the perfusion index played a crucial role in the immediate diagnosis of radial artery embolism in a patient undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy procedure.
Benzo (a) pyrene-loaded gypsum dust induced apoptosis of human bronchial epithelial cells through the AHR signaling pathway
Authors: wang yujun , Lin Qingqing , Lv Zhenzhen , Dong Faqin , Deng Jianjun 
Published: September 2023

Abstract
Objective

To determine the molecular mechanism of human bronchial epithelial cell apoptosis induced by adsorption of organic matter in an air pollutant, solid gypsum dust.

Methods

Benzo (a) pyrene (BaP) was mixed with gypsum dust at a specific ratio (1 µg/g), and human bronchial epithelium (16HBE) cells were selected as the target of infection. Cell survival rate was detected by the CCK8 method and their morphology was observed by Wright-Giemsa staining. Flow cytometry was used to detect apoptosis and the mRNA expression levels of Ahr, Nrf2, Bax, and Bcl-2 were detected by qRT-PCR. The protein expression levels of Ahr, Bax and Bcl-2 were detected by Western blot, while the expression levels of Ahr, Nrf2, Bax and Bcl-2 were detected after pretreatment with geldanamycin.

Results

Compared with gypsum or BaP alone, the 16HBE cells exposed to BaP-loaded gypsum dust had a significantly reduced survival rate that showed a concentration dependent trend. The mRNA expression of Ahr, Bax, and Bcl-2 and the protein levels of Ahr, Bax, and Bcl-2 were increased significantly (P<0.01). However, after geldanamycin pretreatment, the expression of Ahr, Nrf2, Bax, and Bcl-2 (P<0.01) and protein expression levels of Ahr, Bax and Bcl-2 were decreased significantly (P<0.01).

Conclusions

BaP-loaded gypsum dust increases apoptosis of 16HBE cells by reducing the effective dose of BaP. Our results suggest that the mechanism of apoptosis may involve activation of the AHR signaling pathway. However, the corresponding mechanism of this synergistic effect requires further study.
Evaluation of a multi-component early warning system for pastoralist populations in Doolo zone, Ethiopia: mixed-methods study
Authors: Baertlein Luke , Dubad Bashir Ali , Sahelie Birhanu , Damulak Istifanus Chindong , Osman Mohammed , Stringer Beverley , Bestman Agatha , Kuehne Anna , Boetzelaer Elburg , Keating Patrick 
Published: September 2023

Abstract
Background
This study evaluated an early warning, alert and response system for a crisis-affected population in Doolo zone, Somali Region, Ethiopia, in 2019–2021. To adequately cover an area populated by semi-nomadic pastoralist population with sparse access to healthcare facilities, the surveillance system included four components: health facility indicator-based surveillance, community indicator- and event-based surveillance, and alerts from other actors in the area. This evaluation described the usefulness, acceptability, completeness, timeliness, positive predictive value, and representativeness across each of these components.
Methods
We carried out a mixed-methods study retrospectively analysing data from the surveillance system February 2019 - January 2021 along with key informant interviews with system implementers, and focus group discussions with local communities. Transcripts were analyzed using a mixed deductive and inductive approach, with surveillance attributes used as deductive themes.
Results
1010 signals were analysed; these resulted in 168 verified events, 58 alerts, and 29 responses. Most of the alerts (46/58) and responses (22/29) were initiated through the community event-based branch of the surveillance system. In comparison, one alert and one response was initiated via the community indicator-based branch and no alerts or responses via the health-facility indicator-based branch. Positive predictive value of signals received was about 6%. About 80% of signals were verified within 24 hours of reports, and 40% were risk assessed within 48 hours. System responses included new mobile clinic sites, measles vaccination catch-ups, and water and sanitation-related interventions. Focus group discussions emphasized that responses generated were an expected return by participant communities for their role in data collection and reporting. Participant communities found the system acceptable when it led to the responses they expected. Some event types, such as those around animal health, led to the community’s response expectations not being met. Community event-based surveillance was designed to be representative of both settled and semi-nomadic communities.
Conclusions
Event-based surveillance can produce useful data for localized public health action for pastoralist populations. This approach may be better suited to public health surveillance of pastoralist populations than community indicator-based methods. Improvements could include greater community involvement in the system design and potentially incorporating One Health approaches.
Potential Contribution of the Gut Microbiota to the Development of Portal Vein Thrombosis in Liver Cirrhosis
Authors: Huang Xin-yu , Zhang Ying-hui , Yi Shi-yu , Lei Lei , Ma Tao , Huang Rui , Yang Lan , Li Zhen-mao , Zhang Di 
Published: September 2023

Abstract
Background:An imbalance in intestinal homeostasis is observed in patients with liver cirrhosis (LC). Portal vein thrombosis (PVT) is a serious complication of LC that is closely related to intestinal homeostasis. The study aimed to investigate the composition of gut microbiota and its putative role in PVT development in LC.
Methods: 33 patients with LC admitted between January 2022 and December 2022 were enrolled in this study. Based on imaging findings, they were categorized into LC without PVT (n=21) and LC with PVT (n=12) groups. Fecal samples were collected from each participant and underwent 16S rDNA sequencing.
Results: D-dimer and platelet elevations were the main clinical features of LC with PVT. The diversity of the gut bacterial community in the LC with PVT group was found to be significantly higher in both alpha and beta diversity when compared to the control group. The structure of the intestinal microbiota was significantly different between LC with PVT and LC without PVT. Based on LEfSe data, Ligilactobacillusand Enterococcus were identified as the most differentially abundant bacterial taxa in LC with PVT. The fecal microbiota with distinct differences in abundance correlated with coagulation factor parameters. We selected five bacterial genera (Ligilactobacillus, Pseudomonas, Parabacteroides, Lactococcus, and Weissella) to distinguishPVT in LC using a random forest model.
Conclusion:LC with PVT led to a disorder in the intestinal microbiota, which was characterized by an increase in pathogenic bacteria and a decrease in beneficial bacteria. Furthermore, modulating the gut microbiota could be a promising therapeutic approach to reduce the progression of PVT in LC.
Image sharing based on 3D-BCNN and Blockchain Authentication
Authors: Wang Kunshu , Jia Yungang , Zhang Zihua Zhang , Gao Tiegang 
Published: September 2023

Abstract
In the current trend of cloud storage and data sharing, image trading and consumption are increasingly frequent. Therefore, the protection of sensitive images and identity authentication become urgent. In this paper, an image sharing method based on 3-dimensional Boolean convolution neural network (3D-BCNN) and blockchain is proposed. Unlike traditional symmetric encryption algorithms, this paper introduces an asymmetric key cryptosystem, which allow different users to receive image with authorization without knowing the key of the data owner. The correctness authentication of the acquired image is based on blockchain, which is immutable and reliable. In pre-transmission encryption, 3D convolution matrices are designed by Chaotic Restricted Boltzmann Machine(CRBM), convolution kernel and shuffle rule are generated by novel two-parameters wide-range mapping mixed Coupled Map Lattice (TWM-CML), and each channel performs Boolean XOR convolution operation. The experimental simulation shows that the secret image has better security properties than the state-of-the-art algorithms. Furthermore, the algorithm provides an end-to-end trusted image protection system and authenticate efficiently.
Effects of low-level RF fields reveal complex pattern of magnetic input to the avian magnetic compass
Authors: Muheim Rachel , Phillips John B. 
Published: September 2023

Abstract
The avian magnetic compass can be disrupted by weak narrow-band and broadband radio-frequency (RF) fields in the lower MHz range. However, it is unclear whether disruption of the magnetic compass results from the elimination of the perception pattern produced by the magnetic field or from qualitative changes that make the pattern unrecognizable. We show that zebra finches trained in a 4-arm maze to orient relative to the magnetic field are disoriented when tested in the presence of low-level (~ 10 nT) Larmor-frequency RF fields. However, they are able to orient when tested in such RF fields if trained under this condition, indicating that the RF field alters, but does not eliminate, the magnetic input. Larmor-frequency RF fields of higher intensities, with or without harmonics, dramatically alter, the magnetic compass response. In contrast, exposure to broadband RF fields in training, in testing, or in both training and testing eliminates magnetic compass information. These findings demonstrate that low-level RF fields at intensities found in many laboratory and field experiments may have very different effects on the perception of the magnetic field in birds, depending on the type and intensity of the RF field, and the birds’ familiarity with the RF-generated pattern.
Streptococcus equi subspecies zooepidemicus – a case report of sudden death in a German sow farm
Authors: Geiping Lukas , Detlefsen Henrik , Trittmacher Sara , Baums Christoph Georg , Bergmann Rene , Hennig-Pauka Isabel 
Published: September 2023

Abstract
A farm in North-West Germany experienced a high morbidity and mortality in their sow herd. Sows showed fever, lethargy, oedema, mucosal discharge, dyspnoea and abortions. Necropsy revealed a severe fibrinous and purulent polyserositis. Haematological and histological examinations confirmed septicaemia. Streptococcus equi subspecies zooepidemicus was isolated in high yields from major organs. Sequencing typing of this isolate (21/455) revealed a new sequence type showing a significantly higher proliferation rate in comparison to two other isolates. Other infectious diseases (Influenza virus, Porcine Reproductive and Respiratory Virus, Porcine Circovirus 2, African Swine Fever, Classical Swine Fever, Actinobacillus pleuropneumoniae) were excluded by routine diagnostic examinations. A climate check revealed an insufficient air supply in the area for the gestating sows. This case describes the first disease outbreak in swine due to S. zooepidemicus in Germany.
Stochastic Lagrangian-based method for nonconvex optimization with nonlinear constraints
Authors: Papadimitriou Dimitri , Vu Bang 
Published: September 2023

Abstract

The Augmented Lagrangian Method (ALM) is one of the most common approaches for solving linear and nonlinear constrained problems. However, for nonconvex objectives, the handling of nonlinear inequality constraints remains challenging. In this paper, we propose a stochastic ALM with Backtracking Line Search that performs on a subset (mini-batch) of randomly selected points for the solving of nonconvex problems. The considered class of problems include both nonlinear equality and inequality constraints. Together with the formal proof of the convergence properties (in expectation) of the proposed algorithm and its computational complexity, the performance of the proposed algorithm are then numerically compared against both exact and inexact state-of-the-art ALM methods. Further, we apply the proposed stochastic ALM method to solve a multi-constrained network design problem. We perform extensive numerical executions on a set of instances extracted from SNDlib to study its behavior and performance as well as potential improvement of this method. Analysis and comparison of the results against those obtained by extending to nonlinear constraints the method developed in [Contardo2021] for the approximation of separable nonconvex optimization programs are then provided.
Mathematics Subject Classification (2020) 65K05 · 68Q25 · 90C46 · 90C30 · 90C25
Novel mouse model of mixed dementia using chronic cerebral hypoperfusion induced by bilateral carotid artery stenosis
Authors: Kim Jang Hun , Kang Ho-Young , Park Sung Young , Park Dong-Hyuk 
Published: September 2023

Abstract
Background
Alzheimer’s disease (AD) and vascular dementia (VaD) have distinguishable pathognomonic findings, but they are common among older adults with similar clinical manifestations. Clinically, a mixed form of dementia (MD), VaD combined with AD, is frequent in older adults accounting for approximately 50% of all patients with dementia. Owing to the clinical importance and emerging changes in MD, a representative animal model is necessary for future dementia research.
Aims
To develop a novel MD mouse model using bilateral carotid artery stenosis (BCAS) in 5× familial AD (FAD) transgenic mice and establish their behavioral and histological characteristics
Methods
Thirteen C57BL/6 and sixteen 5× FAD transgenic mice were prepared. Six C57BL/6 and seven 5× FAD transgenic mice underwent BCAS surgery, and all mice were raised for 3 months. The mice were divided into four groups: wild-type (n = 7), VaD (n = 6), AD (n = 9), and MD (n = 7). Neurobehavioral tests, including the Y-maze test (YMT), passive avoidance test (PAT), and immunohistochemical confirmation, including mouse monoclonal amyloid-β antibody (MOAB-2) in the cortex/hippocampus and myelin basic protein (MBP) in the corpus callosum, were performed.
Results
Newly developed MD mice demonstrated poor results in YMT, similar to AD and VaD mice, and worse results for PAT compared to the other groups. Immunohistochemical analyses demonstrated that MD mice exhibited amyloid-β protein accumulation in the cortex/hippocampus (MOAB-2) and axonal degeneration in the corpus callosum (MBP).
Conclusion
A novel MD animal model was developed with pathognomonic findings of both AD and VaD. The neurobehavioral spectra of MD mice displayed characteristic deficits in intermediate-term memory and learning ability (PAT).
Histology and ultrastructure of the digestive system in Andean fish (Trichomycterus bogotensis) and ecological implications
Authors: Ruiz Monica Ortiz – , López-Flórez Catalina , Rebolledo Maria Isabel Castro , Baldisserotto Bernardo , Ramírez Edwin Gómez 
Published: September 2023

Abstract

Trichomycterus bogotensis is one of the three species of fish that inhabit the Colombian Andes. However, several aspects of its basic biology, including its digestive system, are unknown. The morphology and histology of the digestive system are of great importance for understanding a species' feeding habits and food preferences. Thus, this study aimed to perform an anatomical and histological description of the digestive tract of T. bogotensis. The gastrointestinal tract of seven specimens was processed for paraffin histology, high-resolution optical microscopy, and transmission electron microscopy. Anatomically, T. bogotensis exhibits a terminal mouth with villiform teeth, a narrow esophagus, a large and muscular stomach, and a short intestine. Histology and ultrastructure revealed a tissue organization similar to that reported for other Silurids, composed of four layers: mucosal, submucosal, muscular, and serosa. The anatomical and histological characteristics suggest that T. bogotensis is a benthic species with a tendency to carnivory.
New Butyl Shikimate Acetal Derivative from Aerial Parts of Acalypha wilkesiana Müll. Mosaica. extracts
Authors: Moustafa Amal M. Youssef , El-damarany Maha , Abdel-Mogib Mamdouh , Yoyussef Magdy 
Published: September 2023

Abstract

The aerial parts of Acalypha wilkesiana gave undescribed potassium 2-butoxyacetimidate (1) and butyl 3(S),4(S),5(R) -4-oxy-3- epishikimic acid carboxylate acetal [(1S,8S, 9R) -8,9-dihydroxy-3-propyl-2,4-dioxabicyclo [4.2.2] dec-6-en-5-one] (2), and shikimic acid, as well as nineteen known glycosylated phenylpropanoids, benzoic acid derivatives and flavonoids. The structures of the isolated compounds were elucidated based on 1D, 2D NMR, and ESI MS.
Analysis of Tip Leakage Vortex Instability and Blade Force in a Low-Speed Compressor Cascade
Authors: Wang Zengzeng , Ma Hongwei , Yang Yi , Zhong Yafei , Zhang Qingdian 
Published: September 2023

Abstract
Turbulence model Detached Eddy Simulation (DES) is utilized to conduct detailed research on the tip leakage flow (TLF) instability and its influence on the compressor cascade blade static pressure distribution. The objectives are to investigate the tip leakage flow instability and blade aerodynamic force oscillation at 0deg incidence design state. This research found that the trailing edge leakage vortex and the secondary leakage vortex mixed with the leakage vortex along the backflow direction and involved into the main leakage flow, which is close to the adjacent blade pressure side. The trailing edge broken tip leakage vortex has influenced the adjacent blade pressure side static pressure distribution and vorticity transformation in the tip region. More substantial convective effects are captured in 0.95span compared with 0.7span, based on the vorticity transport equation, which confirmed the tip leakage vortex caused momentum transfer in the tip region occupies a dominant role among the spanwise. The vortex core identification has revealed the tip leakage vortex wandering in the passage. The data-driven decomposition methods proper orthogonal decomposition (POD) and dynamic mode decomposition (DMD) helped clarify that the tip leakage vortex has a distinct influence on the adjacent blade pressure side static pressure spatial distribution. The frequency spectrum analysis of blade aerodynamic force indicated that some frequency components are close to the monitored tip region velocity. Then, the DMD characteristic frequency and POD time coefficient frequency corresponding with the mode vortex cohesive structure filled the gap in visualizing the vortex structure with its characteristic frequency, which caused the blade aerodynamic oscillation. Tip leakage vortex instabilities and their influence on the blade are well analyzed. Predicted tip leakage vortex instabilities and the blade force oscillation can utilized in the compressor blade vibration design and flow control.
Optimization and Mechanistic Investigation of Electrochemical Performance and Diffusion Behavior of MgFeP 2 O 7 Prepared via Sol-Gel Method in Magnesium Batteries
Authors: Lang Jun , Guangwei Zhang , Wang Guosheng 
Published: September 2023

Abstract
The field of energy storage recognizes the tremendous potential of magnesium-ion batteries (MIBs). It is noteworthy that MgFePO4 has emerged as a promising cathode material for MIBs due to its stability, safety, and cost-effectiveness. However, the linear layered structure of MgFePO4 crystals restricts the diffusion pathway of magnesium ions, resulting in narrow diffusion channels and significant intermolecular coulombic forces. As a consequence, MgFePO4 only achieves a specific capacity of 82mAh/g. To address these limitations, MgFeP2O7 was synthesized using the sol-gel method. Electrochemical characterization of MgFeP2O7 demonstrates a specific capacity of 208mAh/g, approximately 2.5 times that of MgFePO4. Additionally, cycling tests conducted at 1A/g reveal a capacity retention rate of 83.16% after 60 cycles. According to MS software simulations, the synthesized MgFeP2O7 exhibits a porous structure with multiple diffusion pathways, wider diffusion channels, and shorter pathways, ultimately leading to a minimum diffusion barrier of 0.62eV. Furthermore, analysis of the electron cloud density reveals electron transfer occurring between Mg/Mg2+ and Fe3+/ Fe 2+ during the charge-discharge process, while the electron cloud surrounding P5+ remains unchanged. Throughout the charge-discharge process, Fe serves as the redox center of MgFeP2O7.