bluuebunny/crossref_metadata_2025_split huggingface dataset:
Virtual Screening, ADMET Analysis, and Synthesis of 2-(1H-benzotriazol-
1-yl) N- substituted Acetohydrazide that Binds to the Glycoprotein B of
Herpes Simplex Virus-I (HSV-I)
Authors: Mali Dhanashri Revannath , Amrutkar Sunil V. 
Published: July 2023

Background:
Herpes simplex Virus type 1 (HSV-1) is a contagious human pathogen causing severe infection. In recent decades, the virus has become dormant and resistant to available treatment creating the need for the development of new therapeutic agents against it. Benzotriazole is a versatile molecule with a wide range of activities like antibacterial, antiprotozoal, antiulcer, anthelmintic, and antiproliferative activity.

Methods:
A series of 2-(1H- benzotriazole-1-yl) N- substituted acetohydrazide derivatives were synthesized using the method given in the literature. The derivatives were obtained in good yield and characterized by spectral methods of analysis. The antiviral activity against the glycoprotein B of Herpes Simplex Virus-I (HSV-I) was determined using molecular docking (2GUM).

Result:
All compounds had strong binding affinity over the standard Acyclovir. Compound 5h had the highest binding affinity and the highest inhibitory activity.

Conclusion:
The Benzotriazole-N- substituted acetohydrazide derivatives has the highest bind-ing affinity and good inhibition of glycoprotein B of Herpes Simplex Virus-I (HSV-I), which makes it a good antiviral agent.
Experiences and Perceptions of Telehealth Visits in Diabetes Care During and After the COVID-19 Pandemic Among Adults With Type 2 Diabetes and Their Providers: Qualitative Study
Authors: Sun Chun-An , Shenk Zachary , Renda Susan , Maruthur Nisa , Zheng Stanley , Perrin Nancy , Levin Scott , Han Hae-Ra 
Published: July 2023

Background
Since the COVID-19 pandemic, telehealth has been widely adopted in outpatient settings in the United States. Although telehealth visits are publicly accepted in different settings, little is known about the situation after the wide adoption of telehealth from the perspectives of adults with type 2 diabetes mellitus (T2D) and their providers.

Objective
This study aims to identify barriers and facilitators of maintaining continuity of care using telehealth for patients with T2D in a diabetes specialty clinic.

Methods
As the second phase of a multimethod study to understand missed appointments among adults with T2D, we conducted semistructured, individual, in-depth phone or Zoom interviews with 23 adults with T2D (14/23, 61% women; mean age 55.1, SD 14.4, range 35-77 years) and 10 providers from diabetes clinics in a tertiary academic medical center in Maryland. Interviews were audio-recorded, transcribed, and analyzed using thematic content analysis by the research team.

Results
Adults with T2D and their providers generally reported positive experiences with telehealth visits for diabetes care with some technical challenges resulting in the need for in-person visits. We identified the following 3 themes: (1) “perceived benefits of telehealth visits,” such as convenience, time and financial efficiencies, and independence from caregivers, benefits shared by both patients and providers; (2) “perceived technological challenges of telehealth visits,” such as disparities in digital health literacy, frustration caused by unstable internet connection, and difficulty sharing glucose data, challenges shared by both patients and providers; and (3) “impact of telehealth visits on the quality of diabetes care,” including lack of diabetes quality measures and needs and preferences for in-person visits, shared mainly from providers’ perspectives with some patient input.

Conclusions
Telehealth is generally received positively in diabetes care with some persistent challenges that might compromise the quality of diabetes care. Telehealth technology and glucose data platforms must incorporate user experience and user-centered design to optimize telehealth use in diabetes care. Clinical practices need to consider new workflows for telehealth visits to facilitate easier follow-up scheduling and lab completion. Future research to investigate the ideal balance between in-person and telehealth visits in diabetes care is warranted to enhance the quality of diabetes care and to optimize diabetes outcomes. Policy flexibilities should also be considered to broaden access to diabetes care for all patients with T2D.
Analisis Pengaruh Implementasi Standar Akuntansi Pemerintahan Berbasis Akrual dan Kinerja SDM Terhadap Kualitas Laporan Keuangan (Studi Kasus Dinas Lingkungan Hidup Provinsi Sumatera Utara)
Authors: Sari Anita , Wahyuni L Arnida 
Published: July 2023

Penulis melakukan penelitian dengan tujuan memberikan pemahaman mengenai bagaimana pengaruh dari Implementasi standar akuntansi pemerintahan dengan basis akrual juga untuk mengetahui apakah kinerja SDM akan mempengaruhi kualitas laporan keuangan pada keuangan pemerintah Dinas Lingkungan Hidup Provinsi Sumatera Utara. Peneliti menggunakan kuesioner dalam mengumpulkan data dengan total responden sebanyak 15 responden, dan Analisa menggunakan metode kualitatif dan kuantitaif. Analisis data peneliti menggunakan analisis regresi berganda dalam mengetahui pengaruh pada variable. Uji hipotesis yang digunakan adalah uji statistic test dengan menggunakan aplikasi SPSS IBBM 22. Penelitian ini menggambarkan bahwa implementasi SAP dengan basis akrual dan kualitas laporan keuangan memiliki hubungan yang positif. Peneliti juga mendapatkan hasil bahwa kinerja SDM akan akan memberikan pengaruh pada kualitas dan akuntabilitas laporan keuangan. Untuk lebih meningkatkan kualitas SDM yang unggul perlu adanya Diklat yang mengutamakan praktek di lapangan kerja sesuai dengan kebutuhan SDM, dan juga diperlukan adanya perkembangan pada aplikasi keuangan untuk menungkatkan akuntabilitas dan juga kualitas laporan keuangan.
Unique Christian Therapeutic Counseling: Maximizing Results and Shortening Time
Authors: Purba Royal Evendi , Gultom Junifrius 
Published: July 2023

This article describes Christian therapeutic counseling that can help make the counseling process effective. The purpose of Christian therapeutic counseling is not only to want someone to experience recovery from the problem, but above all, the result of the counseling is that the counselee experiences the likeness of Christ who healed him. To get to that stage, one must start with a change in life because one has been freed, freed, recovered, and has personally met God and experienced the likeness of Christ. This can be called unique counseling, maximizing results and shortening time. The research method used is descriptive qualitative. The study's results stated that Therapeutic counseling impacts the process of believers becoming in the image and likeness of God. Counselors must synergize with other fields with different gifts, including the local Church, discipleship team, mission, and pastoral because synergy helps perfect a counselee's recovery and shorten the time.
Emesis induction is successful for recovery of gastric foreign objects in cats
Authors: Fischer Christiana , Chalifoux Nolan , Reineke Erica 
Published: July 2023

Abstract

OBJECTIVE
To prospectively assess the efficacy of emesis induction for the recovery of gastric foreign objects in cats and to determine if any factors influenced recovery.

ANIMALS
22 client-owned cats.

PROCEDURES
Cats for which emesis induction was deemed appropriate were administered an emetic agent by the attending clinician between October 2018 and April 2021. Data collected included whether emesis was successful in recovery in some or all of the foreign object, time from administration to emesis, number of emetic events, and type, length, width, and surface area of the material ingested.

RESULTS
Of the 22 cats that had emesis attempted, 11 (50%) vomited some or all of the foreign object. The time from ingestion to presentation, time from the last meal, presence of food in the vomitus, type of the object, and length, width, and surface area of the object did not influence the likelihood of successful recovery with emesis induction. The most common object cats ingested were rubber bands.

CLINICAL RELEVANCE
Recovery of gastric foreign objects in cats with emesis induction alone may be successful 50% of the time. The type and size of the object is unlikely to influence whether or not emesis will be successful. This information can help prepare cat-owners for expectations and outcomes following attempts at emesis induction.
Strategic Culture and the Russian Federation’s Engagement in the Russia-Ukraine Conflict
Authors: Kogoj Mark 
Published: July 2023

Abstract
The paper examines Russia’s strategic culture and its behaviour in Russia Ukraine conflict between February 2014 and February 2023. It identifies and examines traditional elements of Russian strategic culture, such as territorial expansionism, a tendency towards offensive military action, the perception of the use of military force as an appropriate means to achieve political goals, a paranoid threat perception - the image of the besieged fortress and distrust of the West, fear of coloured revolutions, and the idea of Russia’s greatness and pursuit of international great power status. As the article shows, traditional elements of Russian strategic culture are reflected in and explain Russian Federation’s behaviour in the Russia Ukraine conflict. This pattern confirms the continuity within Russian strategic culture, as its traditional elements are still present and define the contemporary strategic culture of the Russian Federation.
Corrosive synergic effects of acetic acid and atmospheric pollutants on lead and zinc
Authors: Reiser M. , Sihlovec F. , Beaudouin-Goujon L. , Kouřil M. 
Published: July 2023

Abstract
The aim of this paper was to evaluate the possibility of presence of the synergic corrosive effect between acetic acid and chosen air pollutants such as: Cl2, SO2, NaCl, H2S, NH3, NOx. The metals chosen for following experiments were lead and zinc as they are known to be sensitive to volatile organic compounds. Acetic acid occurs often at indoor environment, where other pollutants may be present. The idea was to describe the influence of other pollutants on increasing the corrosion aggressivity of atmosphere contaminated by acetic acid. Synergic effect was found on lead for following pollutants: sulphur dioxide, chlorine, ammonia and nitrogen oxides. And on zinc the found pollutants are: sodium chloride, sulphur dioxide, chlorine, hydrogen sulphide and nitrogen oxides.
Results of application of the technique of the extraperitoneal closure of loop intestinal stoma
Authors: Maistrenko N. A. , Sazonov A. A. , Romashchenko P. N. , Zotov M. V. 
Published: July 2023

The OBJECTIVE was to evaluate the efficacy and safety of the original technique of extraperitoneal closure of a loop intestinal stoma.METHODS AND MATERIALS. A comparative analysis of the results of surgical treatment of 80 ostomy patients who underwent reconstructive and restorative interventions was carried out. The main group included 40 patients operated on according to the original method of extraperitoneal closure of the intestinal stoma. The control group consisted of 40 patients who underwent restoration of the intestinal tract continuity using a standard method with intra-abdominal access.RESULTS. The incidence of postoperative complications in the main and control groups was 10 % and 22.5 %, and the failure of the intestinal anastomosis was 5 % and 7.5 %, respectively (p>0.05). After applying the original technique, this complication in no case led to the development of peritonitis, and the closure of the intestinal fistula was achieved by local treatment. In two patients of the control group, anastomosis failure led to the development of peritonitis, which required relaparotomy with separation of the anastomosis and reformation of the stoma, which prevented the goal of hospitalization from being realized. In the main group restoration of intestinal continuity was achieved in all patients.CONCLUSION. The use of the original technique for extraperitoneal closure of loop intestinal stoma can reduce the incidence of complications, prevent the development of peritonitis in case of anastomosis failure, creating prerequisites for increasing the efficiency of the reconstructive and restorative stage of treatment.
CURRICULUM MANAGEMENT STRATEGIES AND EFFECTIVE IMPLEMENTATION OF UNIVERSAL BASIC EDUCATION IN NIGERIA
Authors: Abdullahi Nimota Jibola Kadir 
Published: July 2023

The main goal of this research was to investigate how curriculum management strategies affected the successful implementation of Universal Basic Education. Total of 712 participants were chosen using proportional random sampling from the sampled primary and junior secondary schools in North-west, Nigeria. The findings of the study demonstrated that students’ mastery goal, effective classroom instruction and evaluation all helped to improve the effectiveness of UBE implementation. Pearson product moment correlation coefficient and linear regression analysis were used to test the hypotheses. Thus, it was recommended that school managers should encourage students' mastery goal so as to help learners to better engaged in the learning process. Likewise, school managers should strive to create effective classroom instruction to help in engaging learner with concepts and process for learning. Furthermore, evaluation of curriculum and learners activities should be done frequently in order to determine learners’ competence before, during and after instruction toward effective implementation of curriculum. Keywords: students' mastery goal; effective classroom instruction, evaluation; self-efficacy; curriculum.
Selective Laser Processing for Functionally Graded Shape Memory Alloy Medical Devices: Process and Applications in Dentistry
Authors: Kuntz Michael L , Ibraheem Khan M. 
Published: July 2023

Abstract
Novel methods for altering the mechanical properties of functionally graded orthodontic medical devices leads to new applications. This article highlights recent applications of selective vaporization to enable functional grading of shape memory alloys in medical devices for the dental industry.
THE INFLUENCE OF COMIC MEDIA BASED ON ADOBE PHOTOSHOP CS ON WRITING SKILLS AND LEARNING INTEREST OF CLASS IV SDN SIDOMULYO STUDENTS 05
Authors: Veni Fitriana 
Published: July 2023

This study aims to determine the effect of comic media based on Adobe Photoshop CS on writing skills and learning interest of fourth grade students of SDN Sidomulyo 05, Silo-Jember District.The phenomenon that exists in grade IV SDN Sidomulyo 05 is that there are several problems found in learning essay writing and a lack of interest in participating in learning activities. The problems encountered include: (a) there are still many students who have difficulty expressing their thoughts, feelings and ideas in writing in writing, (b) not being able to use solid sentences, (c) not being able to use correct spelling, (d) lack of interest in writing activities or tend to get bored easily because there are no more ideas that can be expressed in their writing, (e) students are not active in participating in essay writing activities and joke more with their friends.
This study uses a causal quantitative research approach (cause and effect) in looking at the relationship of variables to the object under study, so that in this study there is an independent variable (X) namely comic media and two dependent variables, namely writing skills (Y1) and interest in learning (Y2). Techniques to determine a sample from a population that has certain characteristics to the desired quota. From this technique the researchers took a sample of class IV as many as 30 students.
With the help of SPSS v.22 the results of the data obtained through the calculation of the SPSS test t-test, the t-count value of the conventional learning method has a value of -2.900 with a probability of 0.008 (sig). The mean difference in the conventional method is -2.30769 with a df of 25. Meanwhile, the t-count value in the comic media based on the Adobe Photoshop CS program is 6.325 with a probability of 0.001 (sig). The number of df is 25 with a mean difference of 4.61538. Meanwhile, from the results of the questionnaire data analysis of interest in learning obtained 0.535, this means that 53.5% of the data both have a positive effect.
Based on the results of analysis and hypothesis testing, data obtained that Ho is rejected, which means that there is an effect of using adobe photoshop-based comic media on students' writing skills and interest in learning
GÖZ KIRPMA TESPİTİ İÇİN YENİ BİR UYARLAMALI EŞİK DEĞERİ ALGORİTMASI
Authors: PEKER Nur Yasin , ZENGİN Ahmet , EROĞLU ERDEM Çiğdem , DEMİRSOY Mert Süleyman 
Published: July 2023

Uykululuk halinin önceden tespit edilmesi, uykululuğa bağlı trafik kazalarını önlemek,
fiziksel ve ekonomik kayıpların önüne geçmek açısından önemlidir. Bir kamera yardımı
ile kişilerin görüntüleri üzerinde görüntü işleme teknikleri uygulanarak uykululuk halini
önceden kestirmek mümkündür. Bu çalışmada, literatürdeki veri kümelerinden
yararlanılarak uykululuk halinin tespit edilmesinde büyük bilgiye sahip olan göz
bölgesinden gelen öznitelikler ile göz kırpma tespiti yapmak için sabit ve uyarlamalı eşik
değerleri ayrı ayrı değerlendirilmiştir. Böylece, kısa süreli göz kırpma ile uzun süreli göz
kapamanın daha iyi ayırt edilmesi hedeflenmiştir. Çalışmada önerilen uyarlamalı eşik
değerinin sabit bir eşik değerinden çok daha başarılı göz kırpma tespiti sonuçları verdiği,
iki farklı veri kümesi üzerinde yapılan deneyler ile doğrulanmıştır.
Strategi Pemasaran Digital Musik Daerah Flores Melalui Platform Musik Digital Spotify
Authors: Wadhi Yohanes Paulus Hanny , Ciptosari Fitri , Siagian Reynaldo Angga 
Published: July 2023

Perkembangan era digital telah mendisrupsi berbagai bisnis, salah satunya adalah industri musik. Para musisi kini semakin mudah memasarkan musiknya tanpa harus menggunakan jasa label rekaman yang proses seleksinya tidak mudah dan berbiaya mahal. Sementara itu, Pulau Flores di Provinsi Nusa Tenggara Timur, yang menyandang predikat baru sebagai Flores The Singing Island memiliki banyak musisi dengan talenta di bidang seni dan musik. Dengan kemajuan digital, lagu-lagu daerah Flores memiliki peluang untuk maju ke kancah dunia. Penelitian ini menggunakan metode deskriptif kualitatif. Penelitian ini melibatkan informan yang merupakan para musisi asli Flores. Hasil dari penelitian ini menunjukkan bahwa salah satu aplikasi digital yang paling berperan dalam upaya pemasaran musik daerah Flores adalah Spotify. Spotify sebagai aplikasi musik digital yang menawarkan fungsi pemasaran bagi para musisi. Aplikasi ini tidak hanya membantu meningkatkan promosi dari setiap produk musik digital, namun juga memberikan pengakuan atas hak cipta dan earning income melalui transaksi royalti bagi para musisi. The development of the digital era has disrupted various businesses, one of which is the music industry. It is now easier for musicians to market their music without having to use the services of a record label whose selection process is not easy and expensive. Meanwhile, Flores Island in East Nusa Tenggara Province, which bears a new title as Flores The Singing Island, has many musicians with talents in art and music. With digital advances, these folk songs have the opportunity to advance to the world stage. This study used descriptive qualitative method. This research involved informants who were native musicians from Flores. The results of this study indicate that one of the digital applications that has the most role in marketing efforts for Flores regional music is Spotify. Spotify as a digital music application that offers marketing functions for musicians. This application not only helps increase the promotion of each digital music product, but also provides recognition for copyrights and earning income through royalty transactions for musicians.
Comparación de la velocidad de alineación entre la ortodoncia fija lingual versus labial. Revisión de literatura
Authors: Veloz Moncada Geraldine Karina , Cabrera Padrón María Isabel , Veloz Moncada Francisco Santiago 
Published: July 2023

Introducción. En la actualidad, los tratamientos ortodóncicos han evolucionado para cumplir objetivos tanto estéticos como funcionales, por medio del desarrollo tecnológico e industrial. Objetivo. Comparar la velocidad entre la aparatología lingual y labial mediante una revisión bibliográfica de la literatura para conocer las diferencias y efectividades de estos dos tratamientos. Metodología. En este estudio se realizó una revisión bibliográfica y documentada sobre la literatura de la ortodoncia lingual y labial y la relación con la velocidad, duración y tiempo de tratamiento. Resultados. Sobre la evaluación de la efectividad y el tiempo total de tratamiento entre aparatos labiales y linguales se demostró que los procedimientos de estas dos aparatologías se complementaron. Conclusión. se pudo concluir que existe una disparidad de los resultados de los artículos analizados con relación a la velocidad y tiempo del tratamiento, tanto de la odontología lingual como labial. Razón por la cual, no se puede afirmar que exista diferencia en eficacia, velocidad, tiempo o duración entre estos dos tratamientos.
Calidad del agua de una playa del Pacífico de Panamá: condiciones fisicoquímicas y bacterias fecales
Authors: Vergara-Chen Carlos , Guevara Belén , Zúñiga Mabel , González Yarisel 
Published: July 2023

Los ambientes marinos a menudo se ven afectados por la contaminación microbiana con implicaciones negativas para la salud humana y ambiental. El objetivo de este trabajo fue describir la calidad del agua de mar de la playa de Río Mar, San Carlos, provincia de Panamá Oeste. Se recolectaron muestras de agua de mar en cuatro (4) zonas de la playa en temporada seca y temporada lluviosa. Se analizaron los parámetros hidrológicos (salinidad, pH, turbidez, sólidos totales disueltos y temperatura), nutrientes (nitrato, nitrito, amonio y fosfato) y BIF (coliformes totales, Escherichia coli y enterococos). Se registraron concentraciones mayores de BIF durante la temporada seca coincidiendo con la mayor afluencia de turistas y usuarios que podría estar causando un aumento en la carga bacteriana en las aguas costeras. Durante la temporada lluviosa las concentraciones bacterianas disminuyeron significativamente. Se encontró una correlación significativa entre la concentración de amonio, la salinidad y la concentración de enterococos, indicando que conforme disminuyó la salinidad aumentó la concentración de amonio y enterococos. Estos resultados deben ser considerados como un diagnóstico parcial, ya que la variabilidad natural ambiental y el incremento de las actividades antropogénicas pueden modificar la calidad de las aguas costeras.