bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding multimodal mobility strategies of micromobility users in urban environments: Insights from Barcelona
Authors: Roig-Costa Oriol , Marquet Oriol , Arranz-López Aldo , Miralles-Guasch Carme , Acker Veronique Van 
Published: August 2023

Abstract

Micromobility, which includes bicycle-sharing systems, e-scooters, and moped-style scooters, has emerged as a popular alternative to traditional transport modes in urban environments, thus expanding the number of transportation options available to urban travellers. Previous research has primarily relied on trip-based data to explore the multimodal character of micromobility. However, existing evidence has failed to understand the ways in which urban travellers have reshaped their mobility strategies as a consequence of the introduction of micromobility. Using a travel survey (N = 902) set in Barcelona, Spain, cluster techniques are used to group micromobility users according to their frequency of use of three different micromobility modes (bicycle-sharing systems, private e-scooter, and moped-style scooter-sharing services). Then, logistic binomial regressions were used, in order to explore each cluster’s usage of traditional modes of transport, along with all potential weekly combinations between modes. Results show that most micromobility users rely on a single type of transport mode on a weekly basis. The models further indicate that e-scooter, shared bicycle, and moped-style scooter users develop different weekly mobility combination strategies. While personal micromobility options (private e-scooter) are associated with monomodal tendencies, sharing services (bicycle sharing and moped-style scooter sharing) encourage multimodal behaviours. These findings contribute to the limited knowledge concerning the role of some micromobility alternatives in creating more rational and less habit-dependent travel behaviour choices.
Mathematical Model of Typhoid Disease Using Standard and Non-standard Finite Difference Schemes
Authors: Irfan Muhammad , Ghour Samer Al , M Kaviyarasu , Mehmood Arif , Saeed Maha Mohammed , Naeem Muhammad , Gul Saeed 
Published: August 2023

Abstract
In the current paper, typhoid disease is mathematically simulated, and its positivity and boundedness are also discussed. The fundamental reproduction number \({R}_{0}\), which is significant in epidemiology, is sorted out. The Lyapunov function for global stability and the Routh-Hurwitz criterion for local stability of the intended NSFD scheme are studied for disease-free and endemic equilibrium points, respectively. The standard finite difference (SFD) scheme and non-standard finite difference (NSFD) scheme are used to approximate the solution of the PSEIT epidemic model.
A Postmortem Case Control Study of Asbestos Burden in Lungs of Malignant Mesothelioma Cases
Authors: Visonà Silvia Damiana , Bertoglio Barbara , Favaron Cristina , Capella Silvana , Belluso Elena , Colosio Claudio , Villani Simona , Ivic-Pavlicic Tara , Taioli Emanuela 
Published: August 2023

Abstract

BACKGROUND
Asbestos lung content is regarded as the most reliable tool for causal attribution of malignant mesothelioma (MM) to previous asbestos exposures. However, there is a lack of studies on asbestos burden in lungs of MM patients in comparison with healthy individuals. This study aims to provide such a comparison, investigating, as well, differences in asbestos lung burden with sex and time trends.
METHODS
Asbestos lung content has been assessed on formalin-fixed lung fragments using scanning electron microscopy coupled with energy dispersion spectroscopy (SEM-EDS) on individuals deceased from MM (cases) and healthy subjects without any lung disease who died from violent causes (controls) between 2005 and 2023.
RESULTS
Asbestos and asbestos bodies (ABs) were found, respectively, in 73.7% and 43.2% of cases and in 28% and 22% of controls; in MM cases the most represented asbestos types were crocidolite and amosite, whereas in controls it was tremolite-actinolite asbestos. The concentration of both asbestos fibers and ABs was statistically significantly higher in MM cases compared to controls. The mean asbestos fibers width was also significantly higher in cases than controls. Males and females with MM showed similar asbestos and ABs concentrations, but females had higher concentrations of chrysotile, and significantly lower fibers width compared to males. Time trends show that MM lung asbestos concentrations decreased starting in 2011.
DISCUSSION
The results suggest a correlation between asbestos burden in lungs and MM risk. The different concentration of chrysotile, as well as the different width of asbestos fibers in MM males and females might reflect a sex difference in response of the lung microenvironment to inhaled asbestos. Finally, this study provides the first pathological evidence of the effect of the ban of asbestos use, demonstrating a significant decrease of asbestos lung content after 2011.
Isolated unilateral oculomotor palsy caused by pure midbrain infarction: a case report
Authors: Chen Zhu-Ling , Zhu Shi-Guo , Liu Rong-Pei , Ma Lu-Lu , Cui Jian , Zeng Guo-Ling , Zhang Xiong , Wang Jian-Yong , Huang Shi-Shi 
Published: August 2023

Abstract
Background: Multiple etiologies may cause oculomotor nerve palsies. Identification of different etiologies is very important for subsequent treatment. Midbrain infarction is a rare cause of oculomotor nerve palsy.
Case presentation: We herein present a case of isolated unilateral oculomotor paresis caused by pure midbrain infarction. Her pupillary sphincter and inferior rectus muscles were selectively spared. The symptoms were completely relieved after two months of antiplatelet therapy.
Conclusion:We proposed that fibers from Edinger-Westphal nucleus and inferior rectus nucleus do not course through the paramedian area of the midbrain. Our report adds to the understanding of fascicles arrangement in the midbrain.
Environmental migration? A Systematic review and Meta-analysis of the literature
Authors: Cipollina Maria , De Benedictis Luca , Scibè Elisa 
Published: August 2023

Abstract
This article provides a comprehensive quantitative overview of the literature on the relationship between environmental changes and human migration. It begins with a systematic approach to bibliographic research and offers a bibliometric analysis of the empirical contributions. Specifically, we map the literature and conduct systematic research using main bibliographic databases, reviews, and bibliometric analysis of all resulting papers. By constructing a citation-based network, we identify four separate clusters of papers grouped according to certain characteristics of the analysis and resulting outcomes. Finally, we apply a meta-analysis to a sample of 96 published and unpublished studies between 2003 and 2020, providing 3,904 point estimates of the effect of slow-onset events and 2,065 point estimates of the effect of fast-onset events.
Overall, the meta-analytic average effect on migration is small for both slow- and rapid-onset events; however, it is positive and significant. Accounting for the clustering of the literature, which highlights how specific common features of the collected studies influence the magnitude of the estimated effect, reveals a significant heterogeneity among the four clusters of papers. This heterogeneity gives rise to new evidence on the formation of club-like convergence of literature outcomes.
JEL Codes: C83, F22, J61, Q51, Q54, Q56.
Corporate tax burden, financing constraints and total factor productivity of enterprises: evidence from A-share listed companies in China
Authors: Li Sumin 
Published: August 2023

Abstract
tax reduction and fee reduction are important measures for China to promote steady economic development and achieve high-quality development. From the perspective of financing constraints, this study uses the data of A-share listed companies in Shanghai and Shenzhen from 2008 to 2019 to analyze the impact of reducing tax burden on total factor productivity of enterprises and its internal financing mechanism under the background of economic downturn. The results show that, on the whole, reducing taxes and fees and reducing the tax burden of enterprises are conducive to improving the total factor productivity of enterprises; Further, the research mechanism shows that reducing the tax burden can reduce financing constraints, increase enterprise cash flow, stimulate enterprise innovation ability, and improve enterprise total factor productivity; The analysis of heterogeneous enterprises shows that the impact of tax reduction and fee reduction on total factor productivity of enterprises is stronger in non state-owned enterprises, enterprises with higher marketization, small and medium-sized enterprises and growing enterprises.
Molecular detection, phylogenetic analysis and genetic diversity of recently isolated foot- and-mouth disease virus serotype A in Egypt
Authors: El-Ansary Ramy E. , Kasem Samy , El-Tabakh Mohamed A. M. , Badr Yassien , Mohamed Imad A. , Abdel-Moneim Ahmed S. 
Published: August 2023

Abstract
Foot-and-mouth Disease (FMD) is a serious contagious viral disease principally affecting all hoof cloven animals. Serotypes A, O and SAT 2 of foot-and-mouth disease virus (FMDV) are circulating in Egypt vaccination. The present study aimed to detect and molecularly characterize FMDV strains circulating in the Northern Egypt during the last 2022 epidemic. RNA was extracted from the epithelial specimens, vesicular fluid and heparinized blood samples from affected animals. Samples were screened using real time reverse-transcription polymerase chain reaction (RT-PCR) that targets RNA-dependent RNA polymerase (RdRp) gene. Positive samples were subjected to individual serotype specific amplification using different set of primers for VP1 of O, A, C and SAT 2 serotypes. Direct sequencing of the positive samples was conducted on positive samples. Biochemical parameters were also screened at time of sampling and at 4, 15 and 30 days. Real time RT-PCR showed positive samples from epithelia and vesicular fluid samples but not the blood of infected animals. Seven out of 16 samples were found positive to FMDV serotype A. Six out of the seven positive samples were classified as serotype A-African topotype-G-IV. Decreases in urea and blood urea nitrogen were detected in infected animals. It was concluded that continuous monitoring of the evolution of circulating the FMDV strains is needed to evaluate and help in vaccine strains selection for controlling FMDV in Egypt.
The pan-cancer analysis uncovers the prognostic and immunotherapeutic significance of CD19 as an immune marker in tumor
Authors: Wei Lanyi , Meng Jingjing , Xiang Danfeng , Yang Quanjun , Zhou Yangyun , Xu Lingyan , Chen Junjun , Han Yonglong 
Published: August 2023

Abstract
The specific cytotoxic effects of anti-CD19 chimeric antigen receptor (CAR) T-cell therapy have led to impressive outcomes in individuals previously treated for B-cell malignancies. However, the specific biological role of CD19(+) target cells, which exert antitumor immunity against some solid tumors, remains to be elucidated. We collected information regarding the level of CD19 mRNA and protein expression from various databases including The Cancer Genome Atlas (TCGA), Tumor Immune Estimation Resource (TIMER), GTEx, and Human Protein Atlas (HPA) for both tumor and normal samples. To evaluate the patients' prognosis according to CD19 expression, a Kaplan-Meier (KM) analysis and univariate Cox regression were performed. Furthermore, using the Estimation of Stromal and Immune Cells in Malignant Tumor Tissues Using the Expression Data (ESTIMATE) algorithm, we estimated the ratio of immune cells infiltrating malignant tumor tissues. Afterward, the GSCALite repository was employed to evaluate the vulnerability of tumors expressing CD19 to drugs used in chemotherapy. To validate the results in clinical samples of certain cancer types, immunohistochemistry was then performed. Most tumor types exhibited CD19 expression differently, apart from colon adenocarcinoma (COAD). The early diagnostic value of CD19 has been demonstrated in 9 different tumor types, and the overexpression of CD19 has the potential to extend the survival duration of patients. Multiple tumors showed a positive correlation between CD19 expression and tumor mutation burden (TMB), microsatellite instability (MSI), ESTIMATE score, immunoscore, and stromal score. Furthermore, a direct association was discovered between the expression of CD19 and the infiltration of immune cells, particularly in cases of breast invasive carcinoma (BRCA). Moreover, CD19 is highly sensitive to a variety of chemotherapy drugs. The study reveals the potential of CD19 as both a predictive biomarker and a target for different cancer immunotherapies.
Effects of silent pituitary adenomas on pregnancy
Authors: Aksu Özge Baş , Demir Özgür , Canpolat Asena Gökçay , Çorapçıoğlu Demet 
Published: August 2023

Abstract
Purpose: Silent pituitary adenomas (SPAs) are a group of hormonally inactive adenomas. The patients do not show clinical signs and symptoms of excess hormones; however, fertility is usually affected in women. The aim of this study was to investigate the possible effects of SPAs on pregnancy.
Methods: Thirty patients with SPAs aged between 18 and 65 years without hormone deficiency or excess were included in the study. We retrospectively evaluated anterior pituitary hormone levels, follow-up periods, pituitary imaging findings, symptoms associated with adenoma size increase during pregnancy, adverse pregnancy outcomes, , delivery procedures, pregnancy week at delivery, birth weight, and lactation duration.
Results: The mean age of the patients was 41.26 ± 9.06 years, and the mean duration after diagnosis was 92.8 months. Of the 30 patients, 7 had macroadenomas, and 23 had microadenomas. The 30 patients had a history of 92 pregnancies, including 12 elective abortions. The incidence of nausea-vomiting and visual impairment during pregnancy were more common in the macroadenoma group (p = 0.016 and p = 0.042, respectively). Spontaneous pregnancy rates were found to be high, and no negative effects of SPAs on fertility were observed. The patients with SPAs did not have an increased risk of pregnancy-related complications compared to the general population, and there were no obvious negative effects on fetal development or lactation. SPAs were not associated with an increased cesarean section rate.
Conclusion: Our findings suggest that SPAs have no negative effects on pregnancy outcomes, fetal development, or lactation.
The burden of persistent symptoms after COVID-19 (long COVID): A Meta-analysis of controlled studies in children and adults
Authors: Azzam Ahmed , Khaled Heba , Refaey Neveen , Mohsen Shorouk , El-Emam Ola Ali , Dawood Nada , Ahmed Hebatalla A. , Soliman Omar A. , Mostafa Sana , Ramadan Heba , Mosa Maha , Elmowafy Amora Omar Ibrahim , Rizk Shimaa Mohamed Abdou , Zaki Ahmed , Hussien Mostafa , Ahmed Ameer , Ezzat Ahmad Ashraf , Hassan Fatma E. 
Published: August 2023

Abstract
Background
Previous meta-analyses estimating the prevalence of the post-COVID-19 condition (PCC) were confounded by the lack of negative control groups. This may result in an overestimation of the prevalence of those experiencing PCC, as these symptoms are non-specific and common in the general population. In this study, we aimed to compare the burden of persistent symptoms among COVID-19 survivors relative to COVID-19-negative controls.
Methods
A systematic literature search was conducted using the following databases (MEDLINE, Web of Science, and Scopus) until July 2023 for comparative studies that examined the prevalence of persistent symptoms in COVID-19 survivors. Given that many of the symptoms among COVID-19 survivors overlap with post-hospitalization syndrome and post-intensive care syndrome, we included studies that compare the prevalence of persistent symptoms in hospitalized COVID-19 patients relative to non-COVID-19 hospitalized patients and in non-hospitalized COVID-19 patients relative to healthy controls that reported outcomes after at least three months since infection. The results of the meta-analysis were reported as odds ratios with a 95% confidence interval based on the random effects model.
Results
Twenty articles were included in this study. Our analysis of symptomatology in non-hospitalized COVID-19 patients compared to negative controls revealed that the majority of symptoms examined were not related to COVID-19 infection and appeared equally prevalent in both cohorts. However, non-COVID-19 hospitalized patients had higher odds of occurrence of certain symptoms like anosmia, ageusia, fatigue, dyspnea, and brain fog (P < 0.05). Particularly, anosmia and ageusia showed substantially elevated odds relative to the negative control group at 11.27 and 9.76, respectively, P < 0.05. In contrast, analysis of hospitalized COVID-19 patients compared to those hospitalized for other indications did not demonstrate significantly higher odds for the tested symptoms.
Conclusions
The persistent symptoms in COVID-19 survivors may result from hospitalization for causes unrelated to COVID-19 and are commonly reported among the general population. Although certain symptoms exhibited higher odds in non-hospitalized COVID-19 patients relative to controls, these symptoms are common post-viral illnesses. Therefore, the persistent symptoms after COVID-19 may not be unique to SARS-CoV-2. Future studies including well-matched control groups when investigating persistent symptoms in COVID-19 survivors are warranted to draw a firm conclusion.
A stable class of finite difference scheme for nonlocal partial differential equation
Authors: Patel Vijay Kumar 
Published: August 2023

Abstract

In this article, a numerical study is introduced for solving the fractional partial differential equation (FPDE) arising from electromagnetic waves in dielectric media (EMWDM) by using an efficient class of finite difference methods. The proposed numerical finite difference scheme is based on the Hermite formula. The Caputo’s fractional derivatives in time are discretized by a finite difference scheme of order O(k (3−α)) & O(k (3−β)), 1 < β < α < 2. The stability and the convergence analysis of the proposed methods are given by a procedure similar to the standard von Neumann stability analysis under mild conditions. Also for FPDE, accuracy of order O k (3−α) + k (3−β) + h 4 is investigated. Finally, several numerical experiments with different fractional-order derivatives are provided and compared with the exact solutions to illustrate the accuracy and efficiency of the scheme. A comparative numerical study is also done to demonstrate the efficiency of the proposed scheme.
Evaluating the Structural and External Validity of a Self-Report Measure of Cognitive Disengagement Syndrome in a Clinical Sample of Adults in Turkey
Authors: Yucens Bengu , Basay Omer , Buber Ahmet , Tumkaya Selim , Basay Burge Kabukcu , Erdem Busra , Becker Stephen P , Burns Leonard G 
Published: August 2023

Abstract

The internal (structural) and external validity of a self-report measure of cognitive disengagement syndrome (CDS, formerly sluggish cognitive tempo) relative to a self-report measure of attention-deficit/hyperactivity disorder-inattention (ADHD-IN) was evaluated with adults from university outpatient psychiatric clinics in Turkey. A total of 274 outpatients (75.9% women; Mage = 31.06; SDage = 10.84; 50.4% anxiety disorders; 41.6% depressive disorders; 2.9% ADHD; 1.5% sleep disorders; 0.7% eating disorders; 2.9% no mental disorder) completed self-report measures of CDS, ADHD-IN, ADHD-hyperactivity/impulsivity (HI), sleep problems, depression, and stress. All 15 CDS symptoms on the Adult Concentration Inventory showed convergent (moderate to high loadings on the CDS factor) and discriminant (loading close to zero on the ADHD-IN factor) validity. CDS also showed stronger first-order and unique associations than ADHD-IN with sleep problems, depression, anxiety, and stress, whereas ADHD-IN showed stronger first-order and unique associations than CDS with ADHD-HI. This is the first study to provide support for the scores from this 15 symptom self-report measure of CDS in a clinical sample of adults, with findings consistent with previous studies examining parent and teacher rating scale measures with the same 15 CDS symptoms. These findings provide additional support for usefulness of these 15 CDS symptoms to study CDS across various cultures.
Rapid weather changes are associated with daily hospital visitors for atrial fibrillation accompanied by abnormal ECG repolarization: A case-crossover study
Authors: Wu Shanmei , Guo Jingyi , Chen Xin , Wang Jie , Zhao Gang , Ma Shixin , Hao Tianzheng , Tan Jianguo , Li Yongguang 
Published: August 2023

Abstract
Background: Atrial fibrillation (AF) is highly prevalent in the population, yet the factors contributing to AF events in susceptible individuals remain partially understood. The potential relationship between meteorological factors and AF, particularly with abnormal electrocardiograph (ECG) repolarization, has not been adequately studied. This case-crossover study aims to investigate the association between meteorological factors and daily hospital visits for AFwith abnormal ECG repolarization in Shanghai, China.
Methods: The study cohort comprised 10,325 patients with ECG-confirmed AF who sought treatment at Shanghai Sixth People's Hospital between 2015 and 2018. Meteorological and air pollutant concentration data were matched with the patient records. Using a case-crossover design, we analyzed the association between meteorological factors and the daily count of hospital visitors for AF with abnormal ECG repolarization at our AF center. Lag analysis models were applied to examine the temporal relationship between meteorological factors and AF events.
Results: The analysis revealed statistically significant associations between AF occurrence and specific meteorological factors. AF events were significantly associated with average atmospheric pressure (lag0d,OR0.9901,95%CI0.9825~0.9977,P<0.05), average temperature (lag1d,OR0.9890,95%CI0.9789~0.9992,P<0.05), daily pressure range (lag7d,OR1.0195,95%CI1.0079~1.0312,P<0.01), and daily temperature range (lag5d,OR1.0208,95%CI1.0087~1.0331,P<0.01). Moreover, a significant correlation was observed between daily pressure range and daily temperature range with AF patients, particularly those with abnormal ECG repolarization, as evident in the case-crossover analysis.
Conclusion:This study highlights a significant correlation between meteorological factors and daily hospital visits for AF in Shanghai, China. Additionally, AF patients with abnormal ECG repolarization were found to be more vulnerable to rapid daily changes in pressure and temperature compared to AF patients without such repolarization abnormalities.
Non-destructive investigation of a late panel painting by Lucas Cranach the Elder
Authors: Cortea Ioana Maria , Ratoiu Lucian , Rădvan Roxana 
Published: August 2023

Abstract
This work presents the results of a complementary diagnostic investigation carried out on a late wooden panel painting attributed to world-famous Renaissance painter Lucas Cra-nach the Elder. The aim of this study was to characterize the pigments, ground layers and painting technique used in Cranach's painting Madonna and Child by means of an integrated non-destruc-tive approach that included Hyperspectral Imaging (HSI), portable X-ray fluorescence (XRF) and Fourier Transform Infrared Spectroscopy (FTIR). Combined XRF and FTIR data allowed identi-fication of a vibrant color palette, with lead white, verdigris, smalt, vermilion, red earth, yellow ochre, and a zinc-rich brown earth among the used pigments. Hyperspectral imaging showed no underdrawings, but various technical features and past restoration interventions were possible to document. The findings provide valuable artistic and technical information regarding the painting materials and style used by this influential 16th-century master, as well as key information that can support the conservation strategy of this remarkable artwork.