bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Kasus Desain Karakter Monster Laut berdasarkan Mitologi Era Renaisans pada Animasi Luca (2021)
Authors: Alifa Nayra Asya , Ratri Dianing 
Published: March 2023

AbstrakMitologi adalah salah satu hal yang seringkali diangkat ke dalam animasi, baik secara terang-terangan maupun tersirat. Luca (2021) merupakan salah satu animasi yang mengangkat unsur mitologi yaitu makhluk mitologi monster laut dari era Renaisans ke dalam aspek cerita dan desain karakternya. Penelitian ini berfokus dalam menganalisis bagaimana unsur mitologi tersebut dituangkan ke dalam aspek desain karakter monster laut pada animasi Luca. Tujuan dari penelitian ini adalah untuk menjadi referensi salah satu dari banyaknya cara untuk menuangkan mitologi ke dalam karya-karya animasi mendatang. Menggunakan analisis deskriptif kualitatif dan metode manga-matrix dari Hiroyoshi Tsukamoto, penelitian ini menganalisis unsur-unsur dari tiap matriks pada desain karakter monster laut Luca dan pada aspek manakah dari desain karakter tersebut dipengaruhi monster laut dari mitologi era Renaisans. Hasilnya adalah desain karakter monster laut Luca banyak mengadaptasi struktur morfologi monster laut dari mitologi renaisans pada matriks bentuk: sisik, sirip, ekor, kaki, dan gigi, juga pada matriks sifat. Selain mitologi, pun ditemukan bahwa desain karakter monster laut Luca juga mengadaptasi struktur morfologi dan sifat dari hewan-hewan laut pada kelas Pisces. Kata Kunci: animasi, desain karakter, mitologi, monster laut AbstractMythology is one of the things that is often brought up into animation, both explicitly and implicitly. Luca (2021) is one of the animations that brought up sea monsters of Renaissance mythology into its aspect of story and character design. This study focuses on analyzing how the mythological elements are poured into the character design aspects of the sea monster characters in Luca. The purpose of this research is to serve as reference for one of the many ways to incorporate mythology into future animation works. Using qualitative descriptive analysis and manga-matrix method from Hiroyoshi Tsukamoto, this study analyzes the elements of each matrix in Luca’s sea monster character design and in which aspects of the character design are influenced by sea monsters from Renaissance mythology. As a result, Luca’s sea monster character design adapts the morphological structure of sea monsters from renaissance mythology on the form matrix: scales, fins, legs, and teeth, also on the personality matrix. Other than mythology, it was also found that Luca’s sea monster character design also adapted the morphological structure and behavior of sea animals in the Pisces class. Keywords: animation, character design, mythology, sea monsters
Perancangan Buku Aktivitas mengenai Ilmu Astronomi untuk Anak Umur 9-12 Tahun
Authors: Khowraiva Alika , Streit Aprilia Kartini 
Published: March 2023

AbstrakAstronomi adalah ilmu pengetahuan yang mempelajari fenomena alam yang terdapat di luar angkasa maupun di dalam Bumi. Pengetahuan ini sangat memiliki peranan penting dalam kehidupan manusia. Dengan astronomi manusia menemukan berbagai penemuan yang menunjang kehidupan seperti pesawat, satelit, dan sebagainya. Tetapi ilmu tersebut dianggap rumit dan masih minimnya sumber informasi mengenai astronomi. Berdasarkan hasil penelitian bahwa anak-anak kurang tertarik dengan media pembelajaran astronomi yang sudah ada karena dianggap membosankan, kalimat yang susah dipahami dan penggunaan teks yang terlalu banyak dibandingkan teks, sehingga tidak meningkatkan minat mereka. Berdasarkan hasil riset media pembelajaran yang disukai anak-anak adalah buku interaktif. Buku interaktif yang dulu sekarang dikenal dengan buku aktivitas, sehingga penulis akan merancang buku aktivitas yang di dalamnya terdapat sebuah aktivitas sains. Perancangan ini menggunakan metode kualitatif-deskriptif, dengan cara mengumpulkan data melalui kuesioner dan studi pustaka. Hasil perancangan ini akan dipublikasikan secara komersial guna memperkenalkan astronomi dengan cara yang berbeda. Kata Kunci: astronomi, media aktivitas, luar angkasa, ilustrasi AbstractAstronomy is the study of natural phenomena found in outer space and on Earth. This knowledge has an important role in human life. With astronomy humans find various discoveries that support life such as planes, satellites, etc. But the science is considered complicated and there is still a lack of sources of information about astronomy. Based on the results of the study that children are less interested in the existing astronomy learning media because they are considered boring, sentences are difficult to understand and the use of text is too much compared to text, so it does not increase their interest. Based on the research results, the preferred learning media for children is interactive books. An interactive book that used to be known as an activity book, so the author will design an activity book in which there is a science activity. This design uses a qualitative-descriptive method, by collecting data through questionnaires and literature studies. The results of this design will be published commercially to introduce astronomy in a different way. Keyword: astronomy, activity media, outer space, illustration
Bergen Insomnia Scale for Adults: The Psychometric Features of the Turkish Version
Authors: BAY Tuba , YALÇIN İlknur , ERGÜN Ayşe 
Published: March 2023

Objective: Insomnia is an important health problem affecting physical, spiritual and social well-being of individuals negatively and it should be early diagnosed as well. The purpose is to appraise the psychometric features of the Turkish version of the Bergen Insomnia Scale (BIS) for adults.
Methods: A total of 495 adults were included in the methodological study in Turkey. Turkish form of BIS was designed within the scope of study conducted in adolescent sample. Construct validity was appraised with exploratory, confirmatory factor analysis, convergent and discriminant validity. Internal-consistency and test-retest analysis were used for reliability.
Results: According to results of explanatory, confirmatory factor analysis; it was identified that BIS showed a two-factor structure as daytime symptoms (α=.85) and nocturnal symptoms (α=.80). Item-total correlations were found as ≥.59 and test-retest correlation as .83.
Conclusions: The Turkish version of the Bergen Insomnia Scale for adults was assessed as valid and reliable.
SISTEM DIAGNOSA PENYAKIT IKAN MENGGUNAKAN METODE CASE BASED REASONING DENGAN ALGORITMA SIMILARITAS SORGENFREI DAN K-NEAREST NEIGHBOR
Authors: Ramadhan Gilang Fadhillah , Winarno Edy 
Published: March 2023

Meningkatnya peminat ikan cupang pada akhir-akhir ini memicu banyaknya orang yang membudidayakan ikan cupang, serta prospek kedepan yang cukup menjanjikan dari setiap tahunnya karena selalu mengalami peningkatan keuntungan. Namun dibalik itu, perawatan ikan cupang bukanlah hal yang mudah dikarenakan ikan cupang merupakan hewan yang mudah terserang penyakit. Dalam usaha menaikkan mutu ikan Cupang serta mengurangi angka kematian akibat penyakit, diperlukan ahli perikanan yang berpengalaman. Banyak pembudidaya yang masih kebingungan dalam menangani ikan cupang yang terserang penyakit, untuk itu dibuatlah suatu sistem yang dapat membantu pembudidaya ikan cupang mengenali penyakit ikan cupang dengan membuat sistem pakar. Metode yang digunakan adalah Case-Based Reasoning dengan menggunakan algoritma similaritas Sorgenfrei, dan ditambah lagi dengan K-Nearest Neighbor. Metode dan algoritma kedua ini dapat digunakan untuk mendiagnosa penyakit dari gejala di database. Berdasarkan penelitian yang sudah dilaksanakan, hasil konsultasi oleh pengguna dengan memilih beberapa gejala-gejala yang dialami menghasilkan nilai kemiripan sebesar 0.8695 dan sistem akan memberi solusi sesuai dengan penyakit.
ANALISIS SERANGAN DHCP STARVATION ATTACK PADA ROUTER OS MIKROTIK
Authors: Ariyadi Tamsir , Nur Riyansyah Aidil , Agung M , Ikrar M. Alzi 
Published: March 2023

Dynamic Host Configuration Protocol (DHCP) adalah protokol client-server yang berfungsi memberikan alamat IP kepada komputer client/ perangkat jaringan secara otomatis. Dalam menggunakan mikrotik OS melakukan analisis lebih lanjut terkait serangan pada DHCP starvation attack. Dimana attacker akan menjadi host pada salah satu komputer dan merequest IP ke mikrotik OS untuk mendapatkan informasi pribadi client yang selanjutnya akan direkam dan dianalisis serangan Man in the Middle. Tentunya hal ini dapat dicegah dengan teknik filtering yang ada pada miktorik OS. Tentunya hal ini dapat dicegah dengan teknik filtering yang ada pada mikrotik OS. Kuncinya dapat dilihat pada komputer hostname yang terdaftar pada mikrotik, sehingga pada proses DHCP Discover yang meminta IP pada DHCP Server mikrotik jika tidak terdaftar hostname nya maka akan di list untuk di blokir.
Synthesis by solid route and physicochemical characterizations of blends of calcium orthophosphate powders and mesoporous silicon particles
Authors: Richard Caroline , Alfred-Arulrasa Mélissa , Ramadas Harikrishnan , Mahagamage Pubudu Tharanga , Defforge Thomas , Gaultier Gael , Autret-Lambert Cécile , Poirot Nathalie , Champion Eric , Magnaudeix Amandine 
Published: March 2023

The purpose of the study was to investigate the synthesis of economic calcium phosphate powders from recycled oyster shells, using a ball milling method. The oyster shell powder and a calcium pyrophosphate powder were used as starting materials and ball milled, then heat treated at 1,050°C for 5 h to produce calcium phosphate powders through a solid-state reaction. Electrochemically synthesized mesoporous silicon microparticles were then added to the prepared phosphate powders by mechanical mixer. The final powders were characterized using X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy to analyze their chemical composition and determine the most suitable process conditions. The biocompatibility of the produced powders was also tested in vitro using murine cells and the results showed good biocompatibility.
Effect of IMU location on estimation of vertical ground reaction force during jumping
Authors: Kerns Jordan A. , Zwart Andrew S. , Perez Pietro S. , Gurchiek Reed D. , McBride Jeffrey M. 
Published: March 2023

Introduction: Several investigations have examined utilizing inertial measurement units (IMU) to estimate ground reaction force (GRF) during exercise. The purpose of this investigation was to determine the effect of inertial measurement units location on the estimation of ground reaction force during vertical jumping.Methods: Eight male subjects completed a series of ten countermovement jumps on a force plate (FP). The subjects had an inertial measurement units attached to the sacrum, back and chest. Ground reaction force was estimated from data from the individual inertial measurement units and by using a two-segment model and combined sensor approach.Results: The peak ground reaction force values for the sacrum, back, chest and combined inertial measurement units were 1,792 ± 278 N, 1,850 ± 341 N, 2,054 ± 346 N and 1,812 ± 323 N, respectively. The sacral inertial measurement units achieved the smallest differences for ground reaction force estimates providing a root mean square error (RMSE) between 88 N and 360 N. The inertial measurement units on the sacrum also showed significant correlations in peak ground reaction force (p &lt; 0.001) and average ground reaction force (p &lt; 0.001) using the Bland-Altman 95% Limits of Agreement (LOA) when in comparison to the force plate.Discussion: Based on assessment of bias, Limits of Agreement, and RMSE, the inertial measurement units located on the sacrum appears to be the best placement to estimate both peak and average ground reaction force during jumping.
Twenty-three medication-taking traits and stroke: A comprehensive Mendelian randomization study
Authors: Shao Wenbo , Li Taozhi , Wang Yukun , Shan Shizhe , Zhang Haiyu , Xue Yanxing 
Published: March 2023

BackgroundCertain medication categories may increase the risk of stroke. Nonetheless, the evidence regarding the causal relationship of medication-taking in promoting stroke and subtypes is deficient.MethodsWe evaluated the causal effect of a genetic predisposition for certain medication categories on stroke and subtypes (ischemic and hemorrhagic categories) by a two-sample Mendelian randomization (MR) analysis. Data for 23 medication categories were gathered from a genome-wide association study (GWAS) involving 318,177 patients. The Medical Research Council Integrative Epidemiology Unit Open GWAS database and the FinnGen consortium were used to gather GWAS data for stroke and subtypes. Inverse variance weighted, MR-Egger, and weighted median were used for the estimation of causal effects. Cochran's Q test, MR-Egger intercept test, and leave-one-out analysis were used for sensitivity analyses.ResultsTen medication categories were linked to a high stroke risk. Nine categories were linked to a high-risk ischemic stroke. Five categories were associated with small vessel ischemic stroke. Nine categories were positively associated with large artery atherosclerotic ischemic stroke. Three categories causally increased the possibility of cardioembolic ischemic stroke. Four categories were associated with intracerebral hemorrhage. Four categories were associated with nontraumatic intracranial hemorrhage. Three categories were causally associated with subarachnoid hemorrhage (SAH). Four categories were associated with the combination of SAH, unruptured cerebral aneurysm, and aneurysm operations SAH.ConclusionsThis study confirms that some medication categories lead to a greater risk of strokes. Meanwhile, it has an implication for stroke screening as well as direct clinical signiﬁcance in the design of conduction of future randomized controlled trials.
A cost-effective o-toulidine-based Schiff base as an efficient sorbent for metal ion uptake from aqueous and soil samples: Synthesis, antimicrobial, and acute toxicity analyses
Authors: Khan Noureen , Jamil Nelofer , Jabeen Rukhsana , Akhtar Malik Muhammad , Ali Hussain , Mehmood Rashad , Orfali Raha , Perveen Shagufta , Peng Jiangnan , Al-Taweel Areej M. 
Published: March 2023

Heavy metals create serious health problems, so the practical implementation and development of low-cost sorbent materials to remove heavy metals from the ecosystem is a worldwide issue. The purpose of this study is to find a low-cost ligand that has the potential to adsorb heavy metals from aqueous and soil samples and also has biological potential. For this, a Schiff base, dimeric o-toluidine (SBL), has been synthesized through condensation, characterized by spectroscopic analysis, and had its biological activities measured. We also studied its adsorption efficiency through a batch technique to remove Zn(II), Co(II), and Cu(II) from aqueous and soil samples under different conditions such as metal ion concentration, pH, contact time, and SBL concentration. The adsorption potential of SBL was analyzed by the Langmuir and Freundlich adsorption isotherms. The values of correlation coefficients revealed that the Freundlich isotherm elucidated results that were more appropriable than the Langmuir model. Adsorption equilibrium was established in 90 min for aqueous samples and in 1,440 min for soil samples. For the maximum adsorption of all metals, the optimum pH was 8, and it showed a capacity to remove 77 to 95 percent of metals from the samples. The maximum adsorption capacity (qmax) of SBL were 75.75, 62.50, and 9.17 mg g-1 in the case of Cu(II), Zn(II), and Co(II) ions, respectively, from aqueous samples and 10.95, 64.10, and 88.49 mg g-1 in the case of Zn(II), Cu (II), and Co(II), respectively, from soil samples. The effectiveness of SBL in the sorption of the selected metals was found to be Cu+2 &gt; Zn+2 &gt; Co+2 for aqueous samples and Co+2 &gt; Cu+2 &gt; Zn+2 for soil samples. The antimicrobial activity of SBL was also investigated. The results revealed that SBL showed moderate inhibitory activity against Staphylococcus dysentria, C. albican, and Aspergillus niger, whereas it exhibited weak activity against S. aureus, P. aureginosa, K. pneumoniae, P. vulgaris, and E.coli when compared to Fluconazole and Ciprofloxacin as the standard. Acute toxicity of the synthesized compound was measured through its daily oral administration with various doses ranging from 0.1 to 1,000 mg/kg of the mice’s body weights. Even at the dose of 1,000 mg/kg, the SBL showed no mortality or any type of general behavioral change in the treated mice. Based on preparation cost, metal removal capacity, toxicity, and antimicrobial activities, SBL is an excellent sorbent and should be studied at pilot scale levels.
Delay in reaching health facilities and its associated factors among mothers giving birth in South Gondar zone hospitals, Northwest Ethiopia, 2020: A facility-based cross-sectional study
Authors: Kassa Bekalu Getnet , Tiruneh Gebrehiwot Ayalew , Solomon Abayneh Aklilu 
Published: March 2023

BackgroundDelays in reaching health facilities are one of three models identified as major contributors to maternal mortality and morbidity in developing countries, including Ethiopia. However, little is known about the prevalence and associated factors of delays in reaching healthcare facilities in Ethiopia, particularly in rural areas.ObjectiveThe aim of this study was to assess the prevalence of delays in reaching health facilities and associated factors among mothers who gave birth in South Gondar zone hospitals, Northwest Ethiopia, 2020.MethodsA cross-sectional study design was used from 28 November to 25 December 2020, with 417 mothers who had recently given birth participating in the study, selected through a simple random sampling technique. Data were collected using a face-to-face interview with pretested structured questionnaires. The EpiData software (version 3.1) was used to record collected data and then exported to SPSS (version 23) for statistical analysis. Bivariable and multivariable analyses were conducted, and the odds ratio with 95% CI was used to identify factors associated with delays in reaching health facilities. The statistical significance was declared at p &lt; .05.ResultsThe prevalence of delay in reaching health facilities among mothers who gave birth in South Gondar zone hospitals were 50.6%. Mothers who had no antenatal care (ANC) visits [adjusted odd ratio (AOR) = 3.16, 95% CI = 1.52, 6.56], an unplanned pregnancy (AOR = 1.78, 95% CI = 1.16, 2.72), and a distance from home to a health facility greater than 5 km (AOR = 1.69, 95% CI = 1.08, 2.65) were positively associated with delays in reaching health facilities.ConclusionsThe prevalence of delays in reaching health facilities was higher in the study area. Women's empowerment through health education about ANC follow-up, choice of family planning methods, and creating accessibility to health facilities are essential measures to minimize delays in reaching health facilities.
Rapid, early, and potent Spike-directed IgG, IgM, and IgA distinguish asymptomatic from mildly symptomatic COVID-19 in Uganda, with IgG persisting for 28 months
Authors: Serwanga Jennifer , Ankunda Violet , Sembera Jackson , Kato Laban , Oluka Gerald Kevin , Baine Claire , Odoch Geoffrey , Kayiwa John , Auma Betty Oliver , Jjuuko Mark , Nsereko Christopher , Cotten Matthew , Onyachi Nathan , Muwanga Moses , Lutalo Tom , Fox Julie , Musenero Monica , Kaleebu Pontiano ,   The COVID-19 Immunoprofiling Team
Published: March 2023

IntroductionUnderstanding how spike (S)-, nucleoprotein (N)-, and RBD-directed antibody responses evolved in mild and asymptomatic COVID-19 in Africa and their interactions with SARS-CoV-2 might inform development of targeted treatments and vaccines.MethodsHere, we used a validated indirect in-house ELISA to characterise development and persistence of S- and N-directed IgG, IgM, and IgA antibody responses for 2430 SARS-CoV-2 rt-PCR-diagnosed Ugandan specimens from 320 mild and asymptomatic COVID-19 cases, 50 uninfected contacts, and 54 uninfected non-contacts collected weekly for one month, then monthly for 28 months.ResultsDuring acute infection, asymptomatic patients mounted a faster and more robust spike-directed IgG, IgM, and IgA response than those with mild symptoms (Wilcoxon rank test, p-values 0.046, 0.053, and 0.057); this was more pronounced in males than females. Spike IgG antibodies peaked between 25 and 37 days (86.46; IQR 29.47-242.56 BAU/ml), were significantly higher and more durable than N- and RBD IgG antibodies and lasted for 28 months. Anti-spike seroconversion rates consistently exceeded RBD and nucleoprotein rates. Spike- and RBD-directed IgG antibodies were positively correlated until 14 months (Spearman’s rank correlation test, p-values 0.0001 to 0.05), although RBD diminished faster. Significant anti-spike immunity persisted without RBD. 64% and 59% of PCR-negative, non-infected non-contacts and suspects, exhibited baseline SARS-CoV-2 N-IgM serological cross-reactivity, suggesting undetected exposure or abortive infection. N-IgG levels waned after 787 days, while N-IgM levels remained undetectable throughout.DiscussionLower N-IgG seroconversion rates and the absence of N-IgM indicate that these markers substantially underestimate the prior exposure rates. Our findings provide insights into the development of S-directed antibody responses in mild and asymptomatic infections, with varying degrees of symptoms eliciting distinct immune responses, suggesting distinct pathogenic pathways. These longer-lasting data inform vaccine design, boosting strategies, and surveillance efforts in this and comparable settings.
Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants
Authors: Sui Yongjun , Andersen Hanne , Li Jianping , Hoang Tanya , Bekele Yonas , Kar Swagata , Lewis Mark G. , Berzofsky Jay A. 
Published: March 2023

IntroductionAdjuvant plays an important role in directing the immune responses induced by vaccines. In previous studies, we have shown that a mucosal SARS-CoV-2 S1 subunit vaccine adjuvanted with a combination of CpG, Poly I:C and IL-15 (named CP15) induced effective mucosal and systemic immunity and conferred nearly sterile protection against SARS-CoV-2 viral replication in macaque models.MethodsIn this study, we used a hamster model, which mimics the human scenario and reliably exhibits severe SARS-CoV-2 disease similar to hospitalized patients, to investigate the protection efficacy of the vaccines against COVID-19 disease. We compared the weight loss, viral loads (VLs), and clinical observation scores of three different vaccine regimens. All three regimens consisted of priming/boosting with S1 subunit vaccines, but adjuvanted with alum and/or CP15 administrated by either intramuscular (IM) or intranasal (IN) routes: Group 1 was adjuvanted with alum/alum administrated IM/IM; Group 2 was alum-IM/CP15-IN; and Group 3 was CP15-IM/CP15-IN.ResultsAfter challenge with SARS-CoV-2 WA strain, we found that the alum/CP15 group showed best protection against weight loss, while the CP15 group demonstrated best reduction of oral SARS-CoV-2 VLs, suggesting that the protection profiles were different. Sex differences for VL and clinical scores were observed. Humoral immunity was induced but not correlated with protection. Moreover, S1-specific binding antibody titers against beta, omicron BA.1, and BA.2 variants showed 2.6-, 4.9- and 2.8- fold reduction, respectively, compared to the Wuhan strain.DiscussionOverall, the data suggested that adjuvants in subunit vaccines determine the protection profiles after SARS-CoV-2 infection and that nasal/oral mucosal immunization can protect against systemic COVID-19 disease.