bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heart transplantation for pediatric foreign nationals in the United States
Authors: Harano Takashi , Sheth Megha , Sasaki Kazunari , Yu Jeremy , Wightman Sean C. , Atay Scott M. , Sainathan Sandeep , Kim Anthony W. 
Published: January 2023

AbstractBackgroundThis study aimed to clarify survival outcomes, waitlist mortality, and waitlist days of heart transplantation of pediatric foreign nationals compared to pediatric United States (US) citizens.MethodsWe retrieved data from March 2012 to June 2021 in the United Network Organ Sharing (UNOS) registry.ResultsOf 5857 pediatric patients newly waitlisted, 133 (2.27%) patients were non‐US citizen/non‐US residents (non‐citizen non‐resident [NCNR]). Patients with congenital heart disease were higher in the US citizen group than in the NCNR group (51.9% vs. 22.6%, p < .001); 76.7% of patients in the NCNR group (102/133) had cardiomyopathy. Of the 133 NCNRs, 111 patients (83.5%) underwent heart transplantation, which was significantly higher than that in the US citizen group (68.6%, p < .001). The median waitlist time was 71 days (IQR, 22–172 days) in the NCNR group and 74 days (29–184 days) in the US citizen group (p = .48). Survival after heart transplant was significantly better in the NCNR group than in the US citizen group (n = 3982; logrank test p = .015).ConclusionsHeart transplantation for pediatric foreign nationals was mostly indicated for cardiomyopathy, and their transplant rate was significantly higher than that in the US citizen group, with better survival outcomes. The better survival outcomes in the NCNR group compared to the US citizen group can likely be attributed to the differing diagnoses for which transplantation was performed.
Factors influencing organ donation in Fujian's Organ Procurement Organization: A retrospective study
Authors: Xie Xianyu , Wu Qinde 
Published: January 2023

AbstractIntroductionThe Organ Procurement Organization (OPO) was established in August 2018. The organization's workload, work efficiency, and quality control of organ donation and procurement have continuously improved, making it one of the most successful OPOs in Fujian Province. This study explores the factors that influence the success and failure of organ donation in Fujian Province, China.MethodsData from 236 potential organ donors registered at an OPO in Fujian Province between January 2020 and May 2022 were retrospectively analyzed.ResultsAmong the 236 potential organ donors, 71 cases of organ donation were successful (30.08% conversion rate). Univariate analysis showed that demographic factors, such as differences in sex, age, marital status, and domicile location, were significantly associated with successful organ donation (p < .05). Among hospital‐related factors, differences in hospital departments were significant (p < .05). Considering disease‐related factors, spontaneous respiration was significant (p < .05). For factors related to organ donation, differences in coordinators were significant (p < .05). Multivariate analysis showed that age, domicile location, spontaneous respiration, and coordinators influenced organ donation success (p < .05). Multifactor analysis revealed that factors, such as age ≤50 years, domicile location in other provinces, no spontaneous respiration, and highly skilled coordinators, could promote successful organ donation.ConclusionsPrograms should clarify the screening criteria for key potential organ donors, enhance the promotion and popularization of organ donation, and boost the number and professional skills of organ donation coordinators to improve the organ donation conversion rate.
Energy‐based evaluation of the stress concentration factor with highly non‐regular coarse meshes: Theoretical formulation and practical validation
Authors: Pontefisso Alessandro , Zappalorto Michele , Berto Filippo 
Published: December 2022

AbstractThe main aim of this work is to propose a simple and highly accurate approach to evaluate the stress concentration factor of notched solids under Mode 1 loading by using non‐regular coarse meshes and the elemental averaged strain energy. As a first step of the analysis, the analytical expression for the Strain Energy averaged over a four‐sided and three‐sided finite element located at the notch tip is derived, taking advantage of Filippi–Lazzarin–Tovo equations for rounded notched plates under pure Mode 1 loading. Subsequently, the accuracy of the proposed approach is widely validated taking advantage of a large number of examples related to U‐shaped notches and rounded V‐shaped notches with different notch root radii.
KNN‐based piezoelectric ceramic multilayer actuators with Ni internal electrodes
Authors: Dong Zhihao , Zhao Peiyao , Cen Zhenyong , Wang Xiaohui 
Published: December 2022

AbstractOn the road of lead‐free piezoelectric ceramics into practical applications, the study of Ni‐internal‐electrode (K, Na)NbO3‐based (KNN‐based) multilayer actuators (MLAs) is an important part, possessing the advantages of environmentally friendly and low cost. The Ni‐internal‐electrode KNN‐based MLAs with different layer numbers and layer thicknesses were fabricated via the tape casting method and sintered in the reducing atmosphere. The piezoelectric layers consist of the main KNN‐based phase and a trace amount of second phase Mn4Nb2O9. The element diffusion between the Ni electrodes and KNN‐based grains is tiny, indicating that Ni is suitable for co‐firing with KNN‐based ceramics. After sintering, the compressive stress perpendicular to the thickness direction and the “relative tensile stress” parallel to the thickness direction are retained in the MLAs, bringing influences on the piezoelectric and dielectric properties of KNN‐based materials. Compared with the bulk ceramics, the prepared MLAs significantly reduce the driving voltages and increase the displacement outputs, which are more applicable to the scenarios of miniaturization and portability. Particularly, the 46‐layer actuator shows high displacements of 1580 and 2737 nm under the voltages of 100 and 200 V, respectively. However, the inverse piezoelectric coefficientd33*for each layer of MLAs is still lower than that of the bulk ceramics, indicating that the piezoelectric properties of the KNN‐based materials are suppressed. To give full play to the piezoelectric properties of KNN‐based materials, more attentions should be paid to the design of reasonable electrode structure and the development of internal electrode paste for MLAs.
Evaluation of the protective nature of GO–BCP nanocomposite coatings on 316L SS in artificial body fluid
Authors: Logesh Mahendran , Marimuthu Arumugam , Ferreira Jose M. F. , Ramakrishnan Praveen , Ballamurugan Anbalagan. M. 
Published: December 2022

AbstractThis work reports on a novel approach to deposit composite coatings based on biphasic calcium phosphate (BCP) incorporating graphene oxide (GO) on 316L stainless steel (316L SS) and on its protective nature against corrosion in the simulated body fluid (SBF). For this purpose, 2‐dimensional GO was successfully incorporated in 1% and 3% weight ratios as mechanical strength enhancer and pore size reducer for the prepared coatings. It was observed that upon increasing the GO content, the corrosion rate was drastically decreased when compared to pristine BCP coating. The corrosion resistance polarization results are in good agreement with the test results obtained for SBF immersion study. The size of the particles has significantly decreased, as shown by transmission electron microscopy (from 190 to 27 nm). The experimental results indicate that the composite hydroxyapatite–β‐tricalcium phosphate–GO (HAp–β‐TCP–GO) coatings enhanced the corrosion resistance of the surgical grade 316L SS, turning it a better implanting option for orthopedic applications.
Ethanol pretreatment and infrared drying of melon: Kinetics, quality parameters, and NIR spectra
Authors: Brandão Shirley Clyde Rupert , da Silva Elaine Maria , de Arruda Guilherme Matheus Pessoa , de Souza Netto José Marcelino , de Medeiros Rafael Augusto Batista , Honorato Fernanda Araujo , Azoubel Patricia Moreira 
Published: December 2022

AbstractThere is a growing interest in drying methods focusing on the reduction of drying time, and improvement of product quality. This work aimed to study the use of ethanol as a pretreatment to melon infrared drying (IRD), evaluating its effect on the drying kinetics and quality parameters. The pretreatment step included the melon immersion in different ethanol concentrations (50% and 100%) and immersion times (10, 20, and 30 min). IRD was performed at 60°C with control (untreated) and pretreated samples. Melon pretreated in 100% ethanol for 30 min had the shortest drying time and highest diffusivity value. The Page model obtained the best fit for the experimental data. All dried melons showed water activity below .60, and a reduction in the bioactive compounds. Samples immersed in 50% ethanol, in general, showed lower losses of total phenolics and carotenoids. Concerning color, there was a decrease in the luminosity (L*), while redness (a*) and yellowness (b*) were intensified. Principal component analysis applied to the near infrared (NIR) spectra of the dried samples showed a tendency of separation between samples pretreated with different concentrations of ethanol. In conclusion, IRD and ethanol pretreatment can be useful tools to reduce drying time, but some limitations on bioactive compounds were discussed.Practical applicationsThe concentration and the time of ethanol pretreatment application can result in different melon infrared drying rates and can influence important qualitative parameters. Therefore, it is important to evaluate these factors to optimize the dried melon production, resulting in lower drying time and better quality preservation.
Genetic and evolutionary dissection of melatonin response signaling facilitates the regulation of plant growth and stress responses
Authors: Gao Yangyang , Chen Huimin , Chen Dongyu , Hao Gefei 
Published: December 2022

AbstractThe expansion of gene families during evolution could generate functional diversity among their members to regulate plant growth and development. Melatonin, a phylogenetically ancient molecule, is vital for many aspects of a plant's life. Understanding the functional diversity of the molecular players involved in melatonin biosynthesis, signaling, and metabolism will facilitate the regulation of plant phenotypes. However, the molecular mechanism of melatonin response signaling elements in regulating this network still has many challenges. Here, we provide an in‐depth analysis of the functional diversity and evolution of molecular components in melatonin signaling pathway. Genetic analysis of multiple mutants in plant species will shed light on the role of gene families in melatonin regulatory pathways. Phylogenetic analysis of these genes was performed, which will facilitate the identification of melatonin‐related genes for future study. Based on the abovementioned signal networks, the mechanism of these genes was summarized to provide reference for studying the regulatory mechanism of melatonin in plant phenotypes. We hope that this work will facilitate melatonin research in higher plants and finely tuned spatio‐temporal regulation of melatonin signaling.
Melancholia, memory, and selfhood in John Banville'sAncient Light
Authors: Qian Rongrong 
Published: December 2022

AbstractThis study focuses on melancholia as a landmark in the interpretation of John Banville'sAncient Lightand attempts to untangle manifestations of the protagonist's melancholy through Freud's concept of the individual's response to a loss, employingMourning and Melancholiaas the theoretical basis. According to Freud, melancholia is an abnormal psychological state in dealing with loss, and it illuminates the representation of the Alex character inAncient Light. In the Freudian sense, each of the memories and expectations in which the libido is bound to the object is brought up and subjected to hypercathexis. Through this lens, I readAncient Lightas an attempt to investigate melancholia's influence over memory, showcasing how melancholia exacerbates memory anomalies for the melancholic individual. Moreover, I utilise a melancholic's identification with the lost object as a ‘loss‐repudiation’ strategy to suggest that melancholia poses a threat to the sense of self.
Implementation of novel polygon‐based obfuscation methods to improve privacy of agricultural data
Authors: Nowbakht Parvaneh , O'Sullivan Lilian , Wall David P. , Holloway Paul 
Published: December 2022

AbstractGeoprivacy protection is a significant concern when sharing data. To support sustainable land management by leveraging existing agricultural data, research is needed to identify how the polygon nature of static field parcels can be obfuscated to allow data sharing among individuals and organizations. In this study, five adaptive polygon‐based obfuscation methods including PN*Rand, PDonut‐k, PDensity‐k, PAHilb, and PDonut_AHilb methods were developed and applied on the Irish Nutrient Management Planning Online (NMP Online) agricultural dataset. The polygon‐based obfuscation methods introduced in this study were designed with the consideration of properties of spatial polygon objects including the spatial coordinates, shape and size of the polygon, topology, and spatial relationship between adjacent polygons that can be used to identify real‐world objects. These methods were developed to guarantee that there is no false‐identification and non‐unique obfuscation which is important for static polygon objects in terms of accuracy and privacy protection. Qualitative approaches were developed to identify the optimal values of inner and outer radii of donut shape based on k‐anonymity satisfaction and subsequently obtain the optimal value of k‐anonymity. Several evaluation methods were implemented to compare the methods performance. Density‐based methods particularly PDonut‐AHilb provide the best trade‐off between field parcel confidentiality and spatial pattern preservation and should be considered for researchers and practitioners obfuscating polygon data.
6-Gingerol Alleviates Ferroptosis and Inflammation of Diabetic Cardiomyopathy via the Nrf2/HO-1 Pathway
Authors: Wu Shenglin , Zhu Jinxiu , Wu Guihai , Hu Zuoqi , Ying Pengxiang , Bao Zhijun , Ding Zipeng , Tan Xuerui 
Published: January 2023

Background. Diabetes mellitus (DM) can induce cardiomyocyte injury and lead to diabetic cardiomyopathy (DCM) which presently has no specific treatments and consequently increase risk of mortality. Objective. To characterize the therapeutic effect of 6-gingerol (6-G) on DCM and identify its potential mechanism. Methods. In vivo streptozotocin- (STZ-) induced DM model was established by using a high-fat diet and STZ, followed by low-dose (25 mg/kg) and high-dose (75 mg/kg) 6-G intervention. For an in vitro DCM model, H9c2 rat cardiomyoblast cells were stimulated with high glucose (

glucose
=
33

mM) and palmitic acid (100 μM) and then treated with 6-G (100 μM). Histological and echocardiographic analyses were used to assess the effect of 6-G on cardiac structure and function in DCM. Western blotting, ELISA, and real-time qPCR were used to assess the expression of ferroptosis, inflammation, and the Nrf2/HO-1 pathway-related proteins and RNAs. Protein expression of collagen I and collagen III was assessed by immunohistochemistry, and kits were used to assay SOD, MDA, and iron levels. Results. The results showed that 6-G decreased cardiac injury in both mouse and cell models of DCM. The cardiomyocyte hypertrophy and interstitial fibrosis were attenuated by 6-G treatment in vivo and resulted in an improved heart function. 6-G inhibited the expression of ferroptosis-related protein FACL4 and the content of iron and enhanced the expression of anti-ferroptosis-related protein GPX4. In addition, 6-G also diminished the secretion of inflammatory cytokines, including IL-1β, IL-6, and TNF-α. 6-G treatment activated the Nrf2/HO-1 pathway, enhanced antioxidative stress capacity proved by increased activity of SOD, and decreased MDA production. Compared with in vivo, 6-G treatment of H9c2 cells treated with high glucose and palmitic acid could produce a similar effect. Conclusion. These findings suggest that 6-G could protect against DCM by the mechanism of ferroptosis inhibition and inflammation reduction via enhancing the Nrf2/HO-1 pathway.
Biochemical Characterization of Partially Stabilized Parthenium hysterophorus L. and Cow Dung Consortium and Its Effect on the Growth Performance of Maize (Zea mays L.)
Authors: Gatew Shetie , Mengistu Andargachew 
Published: January 2023

Parthenium (Parthenium hysterophorus L.) is a major anxious weed found in pastures, wastelands, and agricultural lands. It usually competes very well and reduces crop yield. Up-rooting and herbicides have long been used as management options for weeds. However, these methods are neither economically nor environmentally sound. Another approach is to make compost of it, transforming a problem into an opportunity. Four treatments viz. Parthenium (100%) and Parthenium to cow dung ratio (75 : 25, 50 : 50, 25 : 75 w/w) were partially stabilized for 60 days under aerated conditions. The physical and chemical characteristics of partially stabilized organic materials were analyzed and the effects of the partially stabilized organic materials on the germination and growth performance of maize (Zea mays L.) were assessed. The results revealed that pH, EC, OC, OM, TN,

P

availability, and C/N were not significantly different; this showed an insignificant difference (

P

> 0.05) among the treatments. However, particle densities,

P

availability, EC, OC, and TN were found to be higher in 75 : 25 Parthenium cow dung ratios than in 25 : 75 ratios. Root length, shoot length, and germination index were significantly different among the treatments (

P

≤ 0.05). The seed germination index of maize was the highest (113%) in 75 : 25 ratios of Parthenium and cow dung followed by 50 : 50 ratios (95%) and 25 : 75 ratios (86%); relatively, low germination indices (84.86%) were recorded from partially stabilized organic materials prepared from Parthenium alone. The findings revealed that partially stabilized Parthenium mixed with cow dung could be promising for organic farming and an option for weed management.
Practical Philosophy West and East
Authors: Forster Michael N. 
Published: December 2022

Abstract
This article offers a broad-ranging comparison of practical philosophy in the West and in China with a view to enabling not only better mutual understanding between the two sides but also better self-understanding on each side. Contrary to widespread Western conceptions that Chinese practical philosophy may have contributed some important principles in first-order morality but has contributed little in the area of meta-ethics as compared to the West, it is argued here that Chinese practical philosophy did indeed make important contributions in first-order morality, but that in addition it is generally superior to Western practical philosophy in the area of meta-ethics. There are, however, certain exceptions to this rule on both sides. In the end, therefore, a comparison of the two traditions can contribute not only to a better mutual understanding, but also to a better self-understanding and improvement on each side.
Between and beyond Consequentialism and Deontology: Reflections on Mencius’ Moral Philosophy
Authors: Bai Tongdong 
Published: December 2022

Abstract
Mencius’s account of the yi-li (righteousness-benefit) distinction is important in his moral philosophy, and is often compared with consequentialism or deontology in Western moral philosophy. After showing the problems with a naïve deontological reading and a sophisticated consequentialist reading of Mencius, I will argue that both a really sophisticated consequentialist reading and a non-Kantian deontological reading are more defensible. But they couldn’t address the inequality hidden in Mencius’s moral philosophy, making a Nietzschean reading possible. However, Mencius embraced compassion as a key virtue, which Nietzsche would reject. Mencius’s moral philosophy is doubly bifurcated and different from consequentialism, deontology, and also Nietzsche’s philosophy.
Unexceptional Moral Knowledge
Authors: Williamson Timothy 
Published: December 2022

Abstract
The article defends moral realism against epistemological objections by arguing that if there are moral truths, some of them are known. The claim that moral properties are unknowable because causally inert is shown to be ineffective: none of the main current theories of knowledge requires a causal connection, and anyway moral properties have not been shown to be causally inert. It is explained why a posteriori moral knowledge need not derive from combining a priori moral knowledge with a posteriori non-moral knowledge. The possibility of moral knowledge by perception and by testimony is briefly defended. The role of recognitional capacities for instances of moral properties is emphasized.
“How to Make Athens Closer to Jerusalem”
Authors: Sidharta (戴永富) Leonard 
Published: December 2022

Abstract
Theology and philosophy are strange bedfellows: although they share many similar interests and constantly influence each other, their relationship is fraught with suspicion or even enmity. This problem is especially acute for those who want to harmonize their commitment to sola Scriptura with the use of philosophy in their theology. Drawing insights from Herman Bavinck’s Neo-Calvinist worldview, I argue that this apparent competition is mainly caused by the failure to recognize the organic unity between both disciplines. Without theology, all disciplines would be meaningless, but without philosophy, all disciplines would be unintelligible. Portraying the harmony between theology and philosophy depends on the success of locating the difference and relationship between the universality of theology and that of philosophy. Further, the organicity that suffuses all things and affirms the primacy of special revelation reflects the Neo-Calvinist belief in both sola Scriptura and the sacredness of all vocations.
Short-Term Comparison Between Unilateral Versus Bilateral Percutaneous Pedicle Screw Fixation in Short-Level Lateral Lumbar Interbody Fusion–A Prospective Randomized Study
Authors: Hiyama Akihiko , Katoh Hiroyuki , Sakai Daisuke , Sato Masato , Watanabe Masahiko 
Published: December 2022

Study Design Prospective randomized controlled trial. Objectives No prospective studies have directly compared clinical and radiographic outcomes of unilateral vs bilateral instrumented lateral lumbar interbody fusion (LLIF) for lumbar degenerative disease (LDD). We compared the short-term radiographic, clinical outcomes, and some complications of the unilateral percutaneous pedicle screw (PPS) (UPS) vs bilateral PPS (BPS) fixation in short-level spinal fusion with LLIF for LDD. Methods This was a prospective randomized controlled study of 33 patients who underwent UPS or BPS fixation after LLIF for LDD; 18 patients were assigned to the UPS group and 15 patients to the BPS group. Clinical outcomes, complication rates, and fusion rates were assessed. Results The two groups were similar in age, sex, preoperative diagnosis, and level of surgery. Blood loss, length of hospital stay, and numeric rating scale score one year after surgery did not differ between groups. The operative time was longer in the BPS than UPS group (120.2 vs 88.8 min, respectively; P = .029). Both groups showed improvement in disc height and dural sac in the immediate postoperative computed tomography and magnetic resonance imaging, which did not differ significantly between groups. The subsidence grade and fusion rate did not differ, but cage subsidence was more severe in the UPS than BPS group. Conclusion Unilateral and bilateral PPS fixation after LLIF yielded similar short-term clinical and radiological outcomes. However, severe cage subsidence was more common in the UPS group, which suggests that BPS fixation after LLIF may be a better choice over the long term.