bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pumpkin seed oil–supplemented diets promoted the growth productivity, antioxidative capacity, and immune response in heat-stressed growing rabbits
Authors: Abdelnour Sameh A. , Metwally Mohamed G. E. , Bahgat Laila B. , Naiel Mohammed A. E. 
Published: January 2023

AbstractHeat stress is the most major environmental element contributing to rabbit health problems and reduced production. It is proposed that essential oils be applied to alleviate heat stress-induced oxidative damage in rabbits. The purpose of this feeding trial was to determine the protective impact of pumpkin seed essential oil (PSO)–supplemented diets in reducing the threat of unambient temperature on growing rabbits. Five groups of 5-week-old rabbits were allocated randomly into separated galvanized wire battery. The first group was raised under normal conditions (18 ± 2 °C) and fed a control diet (control group; CNT), whereas the other four groups were exposed to high ambient temperature (38 ± 2 °C) and fed a control diet supplemented with 0 (PSO0.0), 0.5 (PSO0.05), 1.0 (PSO1.0), and 2.0 (PSO2.0) mL PSO/kg diet. Results indicated that all supplemented groups and the positive control have higher live body weight compared with the heat stress group (PSO0.0) at 9 weeks of age. Supplementing of PSO resulted in significant improvement in weight gain at 5–9 weeks and 9–13 weeks compared with PSO0.0 group. The highest feed intake was detected in PSO0.05 group compared with that in other groups. Both PSO2.0 and PSO2.0 groups showed the lowest feed conversion ration compared with other groups. Heat-stressed rabbits given a high dose of PSO (1 to 2 mL) had higher hemoglobin concentrations and lower white blood cell counts throughout the experiment than those given a control diet and subjected to heat stress. All hepatic and renal function parameters improved significantly in the rabbits fed a high dose of PSO as compared to the heat-stressed control group, while protein constituents were significantly higher in experimental groups fed 2 mL PSO compared with other groups. Heat-stressed rabbits administered graded amounts of PSO had the lowest plasma glucose, cortisol, thyroid, and corticosterone concentrations and were noticed to be equivalent to the control group fed unsupplemented diet and reared under normal conditions. The immunohistochemistry analysis demonstrated that rabbit groups reared under heat stress and given 2 mL PSO supplemented diets had negative caspase-3 immunoreactivity surrounding portal tract and normal structure. In conclusion, adding pumpkin seed oil up to 2 mL/kg diet for growing rabbits is indorsed to promote growth as well as antioxidant and immunological status under heat stress conditions.
Evaluation of therapeutic effects of camel milk against the hepatotoxicity and nephrotoxicity induced by fipronil and lead acetate and their mixture
Authors: Abdel-Mobdy Yasmin E. , Abdel-Mobdy Ahmed E. , AL-Farga Ammar 
Published: January 2023

Abstract
Elevated environmental pollution of lead and fipronil is blamed for chronic toxicity. Fipronil and lead acetate are commonly used, but now no adequate data is available concerning the harmful side effects of their mixture. The present work investigated the curative effects of camel milk against lead and fipronil subchronic toxicity individually and as mixture with different doses (1/30 and 1/60 LD50) on male albino rats by oral ingestion. Rats were divided into eight groups; the first group (G1) was the normal health control. G2, G4, G6, and G8 are the normal health groups camel milk. G3 and G4 are ingested by 1/30 LD50 of the fipronil formulation. G5 and G6 are ingested by 1/30 LD50 of lead acetate. G7 and G8 are ingested by 1/60 LD50 of lead acetate and 1/60 LD50 of fipronil formulation. The lead acetate or fipronil and their mixture significantly induced destructive damage to the kidneys and liver function parameters as well as lipid profile and oxidative stress in both organs. Serum LDH activity increased under the same conditions. Most harmful effects were clearly observed in G7 followed by G3 and G5. Histological examination revealed hepatic degeneration and nephropathy in intoxicated rats relative to normal health control, as shown by hypertrophy of hepatocytes in addition to karyomegaly, binucleation, and mild individual cell coagulative and mild hypertrophy, as well as a vacuolar degeneration of tubular epithelium in the kidneys. Both toxicants in their mixture showed more harmful than those of their individual ones. Camel milk treatments into intoxicated animals (lead, fipronil, and mixture groups) attenuated all evaluated parameters, alleviated the harmful influences of the mixture of lead acetate and fipronil, and improved the biomarkers of their oxidative stress.
Management of ground tire rubber waste by incorporation into polyurethane-based composite foams
Authors: Hejna Aleksander , Kosmela Paulina , Olszewski Adam , Zedler Łukasz , Formela Krzysztof , Skórczewska Katarzyna , Piasecki Adam , Marć Mariusz , Barczewski Roman , Barczewski Mateusz 
Published: January 2023

AbstractRapid economic growth implicated the developing multiple industry sectors, including the automotive branch, increasing waste generation since recycling and utilization methods have not been established simultaneously. A very severe threat is the generation of enormous amounts of post-consumer tires considered burdensome waste, e.g., due to the substantial emissions of volatile organic compounds (VOCs). Therefore, it is essential to develop novel, environmentally friendly methods for their utilization, which would hinder their environmental impacts. One of the most promising approaches is shredding, resulting in the generation of ground tire rubber (GTR), which can be introduced into polymeric materials as filler. The presented work is related to the thermomechanical treatment of GTR in a twin-screw extruder with zinc borate, whose incorporation is aimed to enhance shear forces within the extruder barrel. Modified GTR was introduced into flexible polyurethane (PU) foams, and the impact of modification parameters on the cellular structure, static and dynamic mechanical performance, thermal stability, as well as thermal insulation, and acoustic properties was investigated. Emissions of VOCs from applied fillers and prepared composites were monitored and evaluated. Depending on the treatment parameters, beneficial changes in foams’ cellular structure were noted, which enhanced their thermal insulation performance, mechanical strength, and thermal stability. It was proven that the proposed method of GTR thermomechanical treatment assisted by zinc borate particles might benefit the performance of flexible PU foamed composites and hinder VOC emissions, which could broaden the application range of GTR and provide novel ways for its efficient utilization.
Grenzen politischer Repräsentation: Determinanten der Wahlbeteiligung bei Integrationsratswahlen in Nordrhein-Westfalen
Authors: Vierus Paul , Ziller Conrad , Marx Nicole 
Published: January 2023

ZusammenfassungDie Wahl der Integrationsräte auf Kommunalebene ist für Nicht-EU-Ausländerinnen und -Ausländer faktisch die einzige Möglichkeit elektoraler politischer Interessenartikulation. Gleichzeitig sind die politischen Gestaltungsmöglichkeiten von Integrationsräten begrenzt und die Wahlbeteiligung bei Integrationsratswahlen ist typischerweise deutlich geringer als die Wahlbeteiligung bei Kommunalwahlen. Das dadurch entstehende Repräsentationsdefizit für eine substanzielle, in Deutschland lebende Minderheit ist sowohl aus normativ-demokratiebezogenen Gesichtspunkten als auch vor dem Hintergrund der politischen Integration von Zugewanderten problematisch. In dieser Studie untersuchen wir Gründe für die oftmals gering ausfallende Wahlbeteiligung bei Integrationsratswahlen. Aufbauend auf etablierten Theorien zur Wahlbeteiligung beziehen wir allgemeine und migrationsspezifische Faktoren ein und analysieren Strukturdaten aus 2020 für 107 Gemeinden aus Nordrhein-Westfalen – dem Bundesland, in dem rund ein Viertel aller Integrationsräte in Deutschland zu finden sind. Die Ergebnisse der Analysen belegen, dass insbesondere die Involvierung etablierter Parteien sowie eine umfangreiche kommunalpolitische Beteiligungskultur mit einer höheren Wahlbeteiligung bei Integrationsratswahlen einhergehen. Migrationsspezifische Faktoren spielen hingegen eine eher untergeordnete Rolle.
Social Networks and Educational Decisions: Who has Access to Social Capital and for Whom is it Beneficial?
Authors: Lenkewitz Sven , Wittek Mark 
Published: January 2023

AbstractThis article investigates students’ access to social capital and its role in their educational decisions in the stratified German school system. We measure social capital as the availability of highly educated adults in adolescents’ and parents’ social networks. Using panel data on complete friendship as well as parental networks and the educational decisions of more than 2700 students from the CILS4EU-DE dataset, we show that social networks are segregated along socio-economic differences, which restricts access to social capital for socio-economically disadvantaged students. A comparison shows that parental networks tend to be substantially more segregated than children’s friendship networks. In addition, our results indicate that access to social capital is linked to academically ambitious choices—i.e., entering upper secondary school or enrolling in university. This relationship is especially pronounced for less privileged students.
Informiert = Geimpft? Das Informationsverhalten und die COVID-19-Impfentscheidung bei Studierenden
Authors: Schäfer Markus , Stark Birgit , Werner Antonia M. , Mülder Lina M. , Reichel Jennifer L. , Heller Sebastian , Schwab Lisa , Rigotti Thomas , Beutel Manfred E. , Simon Perikles , Letzel Stephan , Dietz Pavel 
Published: January 2023

ZusammenfassungEine zu geringe Impfbereitschaft zählt zu den größten globalen Gesundheitsgefahren und war in der COVID-19-Pandemie auch in Deutschland eine der großen Herausforderungen der öffentlichen Gesundheit. Die Identifikation potenzieller Einflussfaktoren auf das Impfverhalten ist deshalb für eine zielgruppengerechte Gesundheitskommunikation von großer Bedeutung. Studierende sind eine besonders wichtige Zielgruppe der Prävention und Gesundheitsförderung. Der Beitrag geht mit Hilfe einer Online-Befragung der Studierenden einer westdeutschen Universität (n = 1398) im Sommersemester 2021 den Fragen nach, inwieweit sich geimpfte und ungeimpfte Studierende mit hoher bzw. niedrigerer Impfintention hinsichtlich a) ihrer Medien- und Informationsnutzung und b) ihres Vertrauens in Medien und Informationsquellen in der COVID-19-Pandemie unterschieden. Die Ergebnisse zeigen z. T. deutliche Differenzen. Während geimpfte Studierende sich intensiver informierten und hierfür auch stärker auf klassische Medienangebote zurückgriifen, vertrauten insbesondere ungeimpfte Studierende mit niedrigerer Impfintention u. a. mehr auf alternative Nachrichtenseiten und Blogs.
Bioeconomy as a promise of development? The cases of Argentina and Malaysia
Authors: Puder Janina , Tittor Anne 
Published: January 2023

AbstractAll bioeconomy strategies contain certain claims and promises, though these differ from one world region to another. Proceeding from an analysis of bioeconomy debates and the appropriation of the concept by key actors in Argentina and Malaysia, we argue that both countries regard the bioeconomy as a development strategy primarily geared towards the industrial upgrading of agricultural value chains. Its aim is to increase value added in the soy (Argentina) and palm oil (Malaysia) commodity chains by adding further domestic processing steps and developing new branches of industry. This is to lead to social and environmental upgrading and enable the countries to outgrow their subordinate role as biomass exporters. Referring to the world-systems approach and the global value chain literature, we argue that such upgrading strategies must be understood in the context of the hierarchical global division of labour and the position of individual countries in global markets. We show that the promises of industrial, social and environmental upgrading associated with hegemonic bioeconomy visions in Argentina and Malaysia have failed to materialise. Very few new jobs were created, while soybean and palm oil production continue to rely on environmentally harmful techniques. The socioecological long-term costs of the current production model remain unaddressed and unresolved, primarily because property relations and the underlying profit-oriented production model based on mechanisation, monocropping and a greater use of pesticides are never questioned. Should Argentina and Malaysia continue on their current paths, their chances of attaining the bioeconomy’s purported socioeconomic and environmental goals are very slim.
Perception of a need to change weight in individuals living with and beyond breast, prostate and colorectal cancer: a cross-sectional survey
Authors: Heuchan Gabriella N. , Lally Phillippa J. , Beeken Rebecca J. , Fisher Abigail , Conway Rana E. 
Published: January 2023

Abstract
Purpose
People living with and beyond cancer (LWBC) are advised to achieve a body mass index (BMI) within the healthy range (≥ 18.5 and < 25). Not perceiving a need for weight change may be a barrier to achieving a healthy weight. This study aimed to explore factors associated with perceived need for weight change among people LWBC.

Methods
Adults diagnosed with breast, prostate, or colorectal cancer were recruited through National Health Service sites in Essex and London. Participants (N = 5835) completed the ‘Health and Lifestyle After Cancer’ survey, which included a question on perceived need to change weight. Associations between perceived need for weight change and BMI, and perceived need for weight change and health and demographic variables, were analyzed using chi-square tests and logistic regression, respectively.

Results
The proportion of participants perceiving a need to lose weight differed according to BMI category: healthy weight (23%), overweight (64%), obese (85%) (P < 0.001). Having overweight or obesity but not perceiving a need to lose weight was associated with being older, male, non-white, not married or cohabiting, and having cancer that had spread, no formal qualifications, no comorbidities, and having received chemotherapy.

Conclusions
Perceived need to lose weight is prevalent among people LWBC with obesity and overweight. This group may be interested in weight management support. Demographic and health factors were associated with having obesity or overweight but not perceiving a need to lose weight.

Implications for cancer survivors
Weight loss interventions for people LWBC are needed. A subset of people LWBC with overweight and obesity may need additional information or motivators to engage with weight management.
A novel prognostic model of methylation-associated genes in acute myeloid leukemia
Authors: Chen Meiyu , Zeng Zhao , Qin Wei , Cai Xiaohui , Lu Xuzhang , Chen Suning 
Published: January 2023

Abstract
Background
There is growing evidence that methylation-associated genes (MAGs) play an important role in the prognosis of acute myeloid leukemia (AML) patients. Thus, the aim of this research was to investigate the impact of MAGs in predicting the outcomes of AML patients.

Methods
The expression profile and clinical information of patients were downloaded from public databases. A novel prognostic model based on 7 MAGs was established in the TCGA training cohort and validated in the GSE71014 dataset. To validate the clinical implications, the correlation between MAGs signature and drug sensitivity was further investigated.

Results
76 genes were screened out by the univariate Cox regression and significantly enriched in multiple methylation-related pathways. After filtering variables using LASSO regression analysis, 7 MAGs were introduced to construct the predictive model. The survival analysis showed overall survival of patients with the high-risk score was considerably poorer than that with the low-risk score in both the training and validating cohorts (p < 0.01). Furthermore, the risk score system as a prognostic factor also worked in the intermediate-risk patients based on ELN-2017 classification. Importantly, the risk score was demonstrated to be an independent prognostic factor for AML in the univariate and multivariate Cox regression analysis. Interestingly, GSEA analysis revealed that multiple metabolism-related pathways were significantly enriched in the high-risk group. Drug sensitivity analysis showed there was a significant difference in sensitivity of some drugs between the two groups.

Conclusion
We developed a robust and accurate prognostic model with 7 MAGs. Our findings might provide a reference for the clinical prognosis and management of AML.
The effects of preconceptions on directed forgetting - the example of e-learning
Authors: Huang Baolin , Fang Lele 
Published: January 2023

AbstractThis study used the item-based legal forgetting paradigm to investigate the effects of preconception type and material type on directed forgetting, and further explored the effects of preconception on directed forgetting of specific and gist memories through 2 experiments using static textual images and selected dynamic videos as experimental material in a simulated online teaching environment. The results showed that positive preconceptions induced directed forgetting of specific memory, while negative preconceptions enhanced directed forgetting of gist memory only. At the same time, static materials showed a directional forgetting effect, while dynamic materials did not show a directional forgetting effect. Static materials improve individual learning more than dynamic materials.
Equivalent Definitions of Very Strict CD(K,N) -spaces
Authors: Schultz Timo 
Published: January 2023

AbstractWe show the equivalence of the definitions of very strict CD(K,N) -condition defined, on one hand, using (only) the entropy functionals, and on the other, the full displacement convexity class $$\mathcal{D}\mathcal{C}_N$$

D

C
N

. In particular, we show that assuming the convexity inequalities for the critical exponent implies it for all the greater exponents. We also establish the existence of optimal transport maps in very strict CD(K,N) -spaces with finite N.
Safer school with near-UV technology: novel applications for environmental hygiene
Authors: Messina G. , Bosco R. , Amodeo D. , Nante N. , De Palma I. , Petri C. , Cevenini G. 
Published: January 2023

AbstractSystems capable of disinfecting air and surfaces could reduce the risk of infectious diseases transmission. Aim: to evaluate the effectiveness of near-UV LED ceiling lamps, with a wavelength of 405 nm, in improving environmental hygiene. Between November and December 2020, we conducted an experimental study having a pre-post design in a kindergarten room in Siena where 4 ceiling lamps with 405 nm LED technology were installed. Twice per day, sampling was performed before (T0) and after treatment with near-UV (T1). We used between 8 and 12 pairs of contact plates to sample at various random spots each day. Air samplings were also performed. The plates were incubated at 22 and 36 °C. Significance was set at 95% (p < 0.05). The mean level of Colony Forming Unit (CFU) at T(0) was 249 (95% CI 193.1 – 305.0) at 36 °C and 535.2 (374.3 – 696.1) at 22 °C. The reduction was significant at T(1): by 65% at 36 °C and, 72% at 22 °C. Also, for air contamination: 95.3% (98.4—92.3). A dose threshold of about 5 J/cm2 was identified to have an 80% CFU abatement and remains nearly constant. The advantage of being able to use this technology in the presence of people is very important in the context of controlling environmental contamination.
Graphical abstract
Coarse geometric kernels for networks embedding
Authors: Saucan Emil , Barkanass Vladislav , Jost Jürgen 
Published: January 2023

AbstractWe develop embedding kernels based on the Forman–Ricci curvature and intertwined Bochner–Laplacian and employ them for the detection of the coarse structure of networks, as well as for network visualization with applications to support-vector machines (SVMs).
Does poverty increase antibiotic prescribing rates through underlying health conditions? Ecological study using parallel mediation analysis
Authors: Tarkhashvili Nato 
Published: January 2023

Abstract

Objective:
Effect of social determinants on antibiotic prescribing rates is poorly studied in modern literature. The objective of this study was to explore the effect of the prevalence of poverty (annual household income <$24,999) in each state on antibiotic prescribing rates in outpatient settings per 1,000 population through chronic health conditions (ie, prevalence of obesity, diabetes, and chronic obstructive pulmonary disease) while also adjusting for confounders (ie, prevalence of population aged ≥65 years and physician density in each state).

Design:
Ecological study.

Participants:
Entire US population.

Methods:
Prevalence estimates from all 51 states were used to calculate direct, indirect, and total effects of poverty on the rates of antibiotic prescribing through parallel mediation analysis using linear regression with chronic health conditions (obesity, diabetes, and chronic obstructive pulmonary disease) as mediators. I obtained these data from point-prevalence estimates of 2020 survey results from the Behavioral Risk Factor Surveillance System for rates on poverty, obesity, diabetes, chronic obstructive pulmonary disease, and population aged ≥ 65 years. I also used the Antibiotic Resistance & Patient Safety Portal for antibiotic prescribing rates per 1,000 population and the Association of American Medical Colleges database for the physician density per 100,000 population.

Results:
For every percentage increase in prevalence of poverty in each state, the antibiotic prescribing rate increased by 17.4 courses per 1,000 population (95% bootstrap confidence interval, 9.2–24.9) using indirect effects of poverty through mediators.

Conclusions:
Antibiotic stewardship programs should consider targeting social determinants of health along with underlying health conditions of patients being treated with antibiotics.