bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety and Potential Effects of Cannabidiol on Skin Cells
Authors: Tassaneesuwan Natjira , Thammarat Chayanee , Khongkow Pasarat 
Published: January 2023

Objective: Cannabidiol (CBD), a phytochemical active compound from the Cannabis sativa L., has become a popular ingredient in many industries, especially skincare products. However, the scientific evidence supporting its potential skin benefits and safety concerns are still unclear. Therefore, the aim of this study was to investigate the short-term and long-term cytotoxic effects of CBD and its potential melanin-promoting effect on skin cells in order to deeply evaluate the safety of CBD for use in cosmetics. Material and Methods: HaCaT keratinocytes and B16F10 melanoma cell lines were cultured and investigated in regard to the cytotoxicity of cannabidiol in various concentrations (0-10 μg/ml) in the short term and long term by sulforhodamine B (SRB) assay and clonogenic assay, respectively. Next, the cellular melanin production was measured by melanin content assay. The expression of the related genes was accessed by qPCR. Results: The short-term and long-term cytotoxicity studies revealed that CBD at a low concentration was not toxic to skin cells. In addition, CBD could induce melanogenesis in melanocytes by increasing melanin content and upregulating tyrosinase expression. Also, CBD provoked cell proliferation and enhanced vascular endothelial growth factor (VEGF) mRNA expression in keratinocytes. Conclusion: Our study demonstrated that CBD at a low concentration (0.6 μg/ml) is safe for the skin cells in vitro and should thus also be safe if applied to skin. Additionally, CBD could significantly enhance melanogenesis and cell proliferation, which confirms its potential as a cosmeceutical product.
Association between Glucose Metabolism and Oral Combined Contraceptive Pills or Cyclic Progestin in Thai Women with Polycystic Ovary Syndrome: A 3-year Observational Study
Authors: Nualla-Ong Atipath , Wongwananuruk Thanyarat , Angsuwathana Surasak , Techatraisak Kitirat , Rattanachaiyanont Manee , Tanmahasamut Prasong , Indhavivadhana Suchada , Chantrapanichkul Panicha 
Published: January 2023

Objective: To measure the difference in fasting blood glucose (FBG) among Thai women with polycystic ovary syndrome (PCOS), having received either oral combined contraceptive pills (OCP) or cyclic progestin, during 3 years of treatment. Materials and Methods: The data were collected by a retrospective chart review of women with PCOS, who had been treated at Siriraj Hospital before June 2019, backward to the year 2000. The patients were divided into two groups, according to their different treatments, namely: an OCP group and a cyclic progestin group. There were 44 cases in each group, and both groups had received complete hormonal treatment over 3 years. Results: The patients’ baseline characteristics showed a significantly lower body mass index (BMI) and waist circumference (WC) in the OCP group than in the cyclic progestin treatment group. After the 3-year period of treatment, the FBG differences in the OCP group and cyclic progestin treatment group were 3.4±8.4 and 3.6±8.5 mg/dL, respectively; which revealed no statistical significance. Additionally, the difference in the WC and metabolic profile between the studied groups after 3 years of treatment also revealed no significance. However, BMI presented a significant difference between the two hormonal regimens after 3 years of treatment (p-value=0.007), with higher differences in the OCP treatment group. Conclusion: There was no statistically significant difference in FBG between the beginning and at the third year of treatment found in both regimens of hormonal treatment in Thai PCOS women.
Catastrophic and Socioeconomic Disparities Across Different Payment Schemes in Lung Cancer Treatment: A Cross-Sectional Single-Centre Analysis from Thailand
Authors: Geater Sarayut L. , Thongsuksai Paramee 
Published: January 2023

Objective: To identify the magnitude of catastrophic health expenditure (CHE) and medical impoverishment across three payment schemes and compare the within-scheme financial disparity. Material and Methods: A cross-sectional analysis of CHE and medical impoverishment among lung cancer patients was conducted at a university hospital in Thailand. A total of 367 lung cancer patients drawn from three payment schemes were included. The clinical data were collected from the hospital’s Electronic Medical Records, while the socioeconomic data, including cost details, were collected via an interview-based questionnaire from November 2020 to June 2022. Economic analyses were performed using concentration curves and logistic regression modeling. Results: There were 38%, 21% and 27% impoverished patients belonging to the Universal Coverage Scheme (UCS), Social Security Scheme (SSS) and Civil Servant Medical Benefit Scheme (CSMBS), respectively, and approximately further 30% in each scheme became impoverished owing to medical-related expenses. Socioeconomic disparities in CHE; concentration index; CI=-0.36 UCS, -0.59 CSMBS and -0.47 UCS, and medical impoverishment; CI=0.16 UCS, -0.15 CSMBS and 0.10 UCS, were evident in all schemes. These inequities were more pronounced among CSMBS patients. Moreover, if not impoverished already, the probability of medical impoverishment in all payment schemes peaked in the middle quintile and declined thereafter. Conclusion: Across all payment schemes, CHE and medical impoverishment occurred at rates of around 60% and 30%, respectively, among lung cancer patients in Thailand. The gradient of CHE probability was more prominent among CSMBS patients.
Engaging medical laboratory scientists in future pandemics: Lessons from the COVID-19 pandemic in Nigeria
Authors: Makata Victor Chisom , Ekwebelem Moses Chukwuemeka , Essien Victor Godwin , Effiong Fortune Benjamin 
Published: January 2023

The role of medical laboratory scientists has been critical in the early identification of the causative agent of the COVID-19 global pandemic, and the ongoing management and surveillance of the disease. Lessons from the Nigerian experience include the need to improve the capacity of laboratories in molecular diagnosis, increase the number of laboratories within the Nigerian Centre for Disease Control network, and establish more viral laboratories across the country.

Keywords: COVID-19, infectious disease, health care reform, pandemic, medical laboratory scientist
Sarmacja Johannesa Bobrowskiego (1917-1965) w perspektywie geopoetyki. Litewskie reminiscencje
Authors: Gajdis Anna 
Published: January 2023

The subject of the article is Sarmatia in the geopoetical perspective. Lithuanian reminiscences is Bobrowski’s literary output in the context of his concept of Sarmatia, with a special attention towards Lithuanian motives. The writer referred to the vast areas of Central and Eastern Europe from Berlin to the Urals as Sarmatia, and he defined his poetic task as the study of the Germans' transgressions against their eastern neighbours. According to geopoetics, Sarmatia is a place made up of personal experiences, feelings and emotions. Research on the autobiography conducted by M. Czermińska allows us to call it an autobiographical place created out of landscape, history and tradition. The writer himself described East Prussia as a place of childhood and happiness, but he also felt fulfilled as a wanderer on the great expanses of Eastern Europe.
Il faut traiter les faits religieux comme des choses
Authors: Béra Matthieu 
Published: January 2023

Abstract
First, we return to the question of ‘revelation’ that has never been taken as an object of research. There has always been reluctance to take it seriously. However, Durkheim changed his thematic and theoretical perspectives from 1897, focusing on religious facts. Second, we explain how to treat revelation as a ‘thing’, as an object of research, insisting on the exegetical method by positioning ourselves prior to the emergence of ‘revelation’ (1895) to identify the paths that were decisive for Durkheim. All the articles in the special issue follow this approach. Third, we show how Durkheim went about ‘treating religious facts as things’, via the comparative method: by comparing the objectification of religion in other disciplines (history, law, psychology, philosophy), to arrive at a sociological synthesis; by comparing religious facts (and especially sacrifice) within different religions. The six articles in the special issue demonstrate the importance of the comparative method in social science. They ought to be compared with each other.

Résumé
Dans un premier temps, nous revenons sur la question de la révélation en rappelant qu'elle n'a jamais été traitée comme un objet de recherche à part entière. Il y a toujours eu des réticences à la prendre au sérieux. Pourtant, dans les faits, à partir de 1897, Durkheim a bien changé d'optiques, thématique et théorique, en ne s'intéressant plus qu'aux faits religieux. Dans un second temps, nous expliquons comment traiter la révélation ‘comme une chose’, en insistant sur la méthode exégétique, en se positionnant en amont de la révélation (1895), pour repérer les cheminements décisifs de Durkheim. Tous les articles du dossier suivent cette voie. Dans un troisième temps, nous montrons comment Durkheim s'y est pris pour ‘traiter les faits religieux comme des choses’1, via la méthode comparative : en comparant l'objectivation du religieux telle qu'elle était proposée par les autres disciplines (histoire, droit, psychologie, philosophie, ethnologie…), puis en comparant les faits religieux (et spécialement le sacrifice) entre différentes religions. Les six articles du dossier démontrent l'importance de la méthode comparative en science sociale. Ils doivent eux-mêmes être comparés entre eux.
‘La justice est pleine de charité’, ou la ‘révélation’ d'Émile Durkheim vue par Gaston Richard
Authors: Rol Cécile 
Published: January 2023

Abstract
Gaston Richard was not only among the first to be informed of the ‘revelation’ that Durkheim announced about his reading of William Robertson Smith in 1895. Among all the Durkheimians, Richard was alone in publicly declaring himself on the matter. The radical nature of his witness went far beyond the fact of calling into question the date as well as the subject of this ‘revelation’. For Richard, the constitution of Durkheim's religious sociology was ultimately ‘only a moment from a more ample study’ about obligation. The originality of his analysis derives as much from the fact of having seen the main source of Durkheim's inspiration in the neo-criticism of Charles Renouvier (parts 1 and 2) as from having criticized Durkheim's state-sociology, which was, if not the conclusion, then at least its political translation (part 3).

Résumé
Gaston Richard ne fut pas seulement aux toutes premières loges de la ‘révélation’ dont Durkheim fit part au sujet de sa lecture de William Robertson Smith, en 1895. De tous les durkheimiens, il fut encore le seul à s'y prononcer publiquement. La radicalité de son témoignage ira bien au-delà du fait de remettre en cause la date tout autant que l'objet de cette ‘révélation’ : pour Richard, la constitution de la sociologie religieuse durkheimienne ne fut en définitive ‘rien qu'un moment d'une étude beaucoup plus ample’ sur l'obligation. L'originalité de son analyse tient autant au fait d'en avoir vu la source d'inspiration majeure dans le néo-criticisme de Charles Renouvier (parties 1 & 2) que dans celui d'avoir critiqué la sociologie durkheimienne de l'État, qui en était sinon la conclusion, du moins la traduction politique (partie 3).
Émile Durkheim et la sociologie des religions
Authors: Fhima Catherine , Lardinois Roland 
Published: January 2023

Abstract
This article examines Henri Hubert and Marcel Mauss's Essay on the nature and function of sacrifice, published in the second volume of L'Année sociologique edited by Durkheim. By focussing on the comparative method used by Hubert and Mauss to compare the civilisations of ancient India and Israel, we can trace how Durkheim gradually elaborated upon the sociology of religions and the subject of sacrifice. Two sociological concepts are used to analyse this intellectual exchange. First, the notion of ‘configuration’, following Norbert Elias, that is understood as a space of mutual dependence and interaction in which authors, journals, disciplines and academic institutions participate. Second, the notion of ‘a conversational space’, borrowed from Erving Goffman, that formed among Émile Durkheim, Marcel Mauss, Henri Hubert and Sylvain Lévi. We contend that the writing and thinking of sacrifice in Hubert and Mauss's essay was marked by the different backgrounds to which these four scholars belonged—three Jews and one Christian—while at the same time they were committed in the name of justice and equality to the defence of Captain Dreyfus, seen as an ‘expiatory victim’.

Résumé
Le but de cet article est d'étudier la fabrique de l'ouvrage d'Henri Hubert et de Marcel Mauss, Essai sur la nature et la fonction du sacrifice, paru en 1899 dans le deuxième volume de L'Année sociologique éditée par Émile Durkheim. On montre que ce mémoire est le résultat des échanges intellectuels entre Henri Hubert, Marcel Mauss, Émile Durkheim et Sylvain Lévi, ce dernier ayant fourni aux auteurs de l'essai une analyse du sacrifice védique qui structure leur modèle. On mobilise deux outils sociologiques : premièrement, la notion de configuration, empruntée à Norbert Elias et, deuxièmement, celle d'ordre conversationnel que l'on doit à Erving Goffman. On soutient que l'Essai sur le sacrifice témoigne d'une écriture de la différence à laquelle participent trois savants juifs et un savant de culture chrétienne, ces quatre personnes étant par ailleurs engagées dans la défense du capitaine Dreyfus au nom de la justice et de l'égalité.
The ‘Revelation’ in Durkheim's Sociology of Religion
Authors: Miller William Watts 
Published: January 2023

Abstract
What was the nature of the ‘revelation’ and of the appreciation of William Robertson Smith that, in 1907, Émile Durkheim dated to 1895? This article tracks new developments in his thought after 1895, including an emphasis on creative effervescence. But there was also continuity, involving a search for origins that used the ethnology of a living culture to identify early human socioreligious life with totemism in Australia. It is this continuity, at the core of his thought after 1895, which helps to bring out the nature of his ‘revelation’ and of his homage to Robertson Smith. It also highlights a problem with his start from an already complex Australian world, yet without a suitable evolutionary perspective available to him. However, a modern re-reading can reinstate Durkheim's interest in origins, in a story of hominin/human evolution over millions of years.
Modi's Journey from a Chowkidar (Watchman) to Great God
Authors: Raja Anand 
Published: January 2023

Abstract
Indian Prime Minister Narendra Damodardas Modi uses self-reflexive symbols. He called himself Watchman and weaved a campaign around it. This article sees Modi's campaign alongside Durkheim's The Elementary Forms of Religious Life: emergence of Modi's Watchman image as a totem, emergence of a clan of believers, collective effervescence, coming of a civilising hero, and Modi becoming a great god. The totem and the clan ‘disappeared’ on the last day of the elections. Only the great god remained to resurrect in millions of banners in public spaces saying: ‘Thank you, PM Modi’. This journey of this Dionysian election campaign with emotive symbols and meticulously planned spectacles built an illusion of a society with religion in its elementary form replacing the modern society for the election period.
ADAPTAÇÃO ACADÊMICA NO ENSINO SUPERIOR: ESTRATÉGIAS DE ENFRENTAMENTO DIANTE DOS PROCESSOS AVALIATIVOS
Authors: Anjos Thiago Vinícius dos , Rego Maria Luiza da Cunha , Viana Kilma da Silva Lima 
Published: January 2023

Todo o tempo vivenciamos experiências, programadas ou inesperadas, tornando-se necessário adaptar-se às novas circunstâncias. Sendo o ingresso às universidades e faculdades e seus novos formatos avaliativos, estruturais e burocráticos uma quebra da previsibilidade e controle na vida de grande parte do corpo estudantil, buscamos compreender de que forma o processo avaliativo impacta essa vivência e quais possíveis estratégias de enfrentamento (coping) são acionadas na adaptação acadêmica diante da relação estudante-avaliação. A pesquisa quantiqualitativa de natureza aplicada, exploratória e descritiva, foi realizada no ano de 2021 e utilizou um questionário individual, tendo como participantes 38 estudantes do curso “Ciências Sociais (Licenciatura)”, da Universidade Federal de Pernambuco (UFPE). Neste estudo, foram identificados baixos índices no nível Pessoal de vivência acadêmica, marcada pela baixa sensação de bem-estar e saúde física e mental, bem como a recorrente associação das avaliações como fonte de sentimentos majoritariamente negativos. No nível Estudo, estudantes mulheres demonstraram maiores percentuais para lidar com a gestão e organização do tempo e enfrentar mais ativamente os estressores advindos do processo avaliativo. A principal estratégia de coping utilizada é a focada no problema, principalmente entre concluintes e pessoas que detestam realizar avaliação. Nota-se ainda uma tendência de estudantes com menos tempo na instituição se isolarem e não buscar suporte social. Por fim, o suporte provindo da dimensão espiritual se mostra como positivo pela capacidade de promover o conforto e ressignificação de situações, apontando à importância do autoconhecimento e autocuidado como promotores de bem-estar e ferramentas protetoras frente às solicitações de desamparo.
STRATEGI PERPUSTAKAAN DESA RAHUL DALAM IMPLEMENTASI PROGRAM INKLUSI SOSIAL MENJADI PERPUSTAKAAN TERBAIK NASIONAL
Authors: Boby-Prabowo  , Batubara Abdul Karim , Jamil Khoirul 
Published: January 2023

ABSTRAK
Penelitian dituliskan dengan judul “Strategi Perpustakaan Desa Rahul Dalam Implementasi Program Inklusi Sosial Menjadi Perpustakaan Terbaik Nasional”, pada tahun 2020 perpustakaan desa ini mendapat penghargaan tingkat nasional sebagai Perpustakaan Desa Terbaik dalam Implementasi Program Transformasi Perpustakaan Berbasis Inklusi Sosial. Maka dari itu, penulis tertarik untuk meneliti bagaimana Perpustakaan Desa Rambung Sialang Hulu merancang strategi mereka untuk bisa meraih prestasi nasional tersebut. Penelitian ini menggunakan pendekatan deskriptif dengan metode penelitian kualitatif, dengan hasil penelitian yang didapat ialah ada beberapa langkah yang harus dilakukan untuk implementasikan hal tersebut.
Kata kunci: perpustakaan desa, implementasi, inklusi sosial.
ЗАСТОСУВАННЯ НОВІТНІХ ОСВІТНІХ ТЕХНОЛОГІЙ У ПІДГОТОВЦІ ВЧИТЕЛЯ ПОЧАТКОВИХ КЛАСІВ ДО ФОРМУВАННЯ СОЦІАЛЬНОЇ КОМПЕТЕНТНОСТІ УЧНІВ МОЛОДШИХ ШКОЛЯРІВ
Authors: ШПИЧКО Інна , КАЗАКОВА Наталія 
Published: January 2023

Актуальність особистісно-орієнтований підхіду в освіті зростає як наступний крок у процесі вдосконалення і встановлення балансу між освітою та вимог сьогодення. Суспільство від сучасного учителя початкових класів очікує високий рівень креативності, самостійність і логічність мислення, толерантність, емпатійність і сформованість таких ключових компетентностей, як соціальна, комунікативна, інструментальна, дослідницька, інформаційна.
Вище зазначене і породило зміни в освіті, змінивши вектор її цілей та поєднавши не лише підготовку професійного, конкурентоспроможного учителя, затребуваного на ринку освіти, а й компетентної особистості, яка готова у різних ситуаціях стрімко прийняти правильне рішення, практично застосувавши одержані знання та ефективно взаємодіяти з іншими.
СОЦІАЛЬНА ПІДТРИМКА СОЦІАЛЬНО-ПСИХОЛОГІЧНИХ СЛУЖБ ВІЙСЬКОВОЗОБОВ’ЯЗАНОЇ МОЛОДІ, ФОРМИ РОБОТИ
Authors: ДЖИГУН Людмила , БЕРЕГОВА Наталія , ІГУМНОВА Ольга 
Published: January 2023

Психологічна робота є узгодженою, цілеспрямованою діяльністю військових психологів, інших посадових осіб органів по роботі з особовим складом, командирів (начальників), штабів щодо формування у військовослужбовців психологічних якостей, що забезпечують виконання завдань в різних умовах, збереження психічного здоров’я військовослужбовців, членів їх сімей, працівників Збройних Сил України.
Досвід організації психологічної роботи переконливо свідчить, що серед військовослужбовців є особи, які потребують посиленої соціальної психологічної уваги та індивідуальної психологічної допомоги, (підтримки) для подолання особистісних психологічних проблем.
Основними напрямами роботи щодо надання соціально психологічної допомоги, підтримки, військовослужбовцям, є якомога точніше визначення сутності їхніх психологічних проблем шляхом соціально-психологічного вивчення та психологічного обстеження; визначення способів вирішення цих проблем (як правило, через створення індивідуальної програми психокорекційних та/або тренінгових заходів); впровадження визначених способів у формі конкретного психологічного впливу і, як головна мета такої роботи, – досягнення стабілізації та позитивної динаміки психоемоційних станів.
Antibacterial effect of ethanol extract of nutmeg against foodborne disease pathogens
Authors: Astuty Eka , Sukmawaty Eka 
Published: January 2023

Foodborne disease is a disease that occurs as a result of food contamination by microbes or harmful chemicals. Nutmeg (Myristica fragrans Houtt.) is widely used as a spice and flavor enhancer for food and beverages. In addition, it has traditionally been used to treat diarrhea and kidney disease. Several pharmacological studies have reported the antioxidant, antimicrobial, antidiarrheal and anti-inflammatory activity of this plant. Antibacterial effectiveness test of nutmeg against several pathogens in this study was carried out using the disc diffusion method. The results of this study indicated that the ethanol extract of flesh of fruit (concentration of 5%, 10%, 15%, 20%, and 25%) had antibacterial activity against all tested pathogenic bacteria. Different results were shown by the ethanol extract of seed and mace. All the ethanol extract concentrations of seed were not able to inhibit the growth of Shigella sp. and Clostridium sp., while the ethanol extract of mace in all concentrations was unable to inhibit the growth of Shigella sp. Various factors may affecting this extract and compound activity when used in complex biological systems such as in vivo and human studies. Future studies must also focus on aspects of pharmacokinetics and toxicological plant extracts and phytochemicals.
Pengaruh Jenis Pupuk Organik Padat terhadap Pertumbuhan, Hasil dan Serapan N Tanaman Cabai, Tomat dan Caisin pada Inceptisols Sumbang
Authors: Noorhidayah Ratri , Maryanto Joko , Rohadi Slamet 
Published: January 2023

<p>Beragam bahan pembuat pupuk organik memiliki karakteristik fisik, kimia dan biologi yang berbeda-beda, demikan juga dengan kandungan unsur haranya. Hasil penelitian sebelumnya menunjukkan belum adanya spesifikasi jenis pupuk organik terhadap macam tanaman sayuran. Penelitian dilakukan di lahan Inceptisols Sumbang selama bulan Juni hingga Oktober 2019 dan bertujuan untuk mengetahui 1) tingkat efisiensi dan serapan N berbagai jenis pupuk organik padat pada tanaman cabai, tomat dan caisin dan 2) pengaruh jenis pupuk organik padat terhadap pertumbuhan dan hasil tanaman cabai, tomat dan caisin. Penelitian disusun dalam rancangan petak terbagi dengan 5 jenis pupuk organik padat dan 3 jenis tanaman sayur. Hasil penelitian menunjukan bahwa pupuk organik kompos lengkap paling baik bagi produksi tanaman caisin dan pupuk kotoran ayam paling baik untuk produksi tanaman tomat dan cabai.</p>