bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFECTIVENESS OF HIBISCUS SABDARIFFA ON BLOOD PRESSURE OF HYPERTENSION PATIENTS
Authors: Harmili Harmili , Fadlilah Siti , Sucipto Adi 
Published: July 2023

To prevent the dangers of hypertension, it is necessary to maintain blood pressure. Natural ingredients for non-pharmacological hypertension therapy are rosella flowers. Rosella (Hibiscus sabdariffa) contains flavonoids, as a diuretic, lowers blood pressure, lowers blood viscosity and stimulates bowel movements. The anthocyanins contained in rosella have an antihypertensive effect. This study aims to determine the effect of rosella flowers on blood pressure in hypertensive patients. This type of research is a quasy experiment with a Pre Test and Post Test Nonequivalent Control Group. The sample was 18 people in the control group and 17 people in the intervention group. The intervention sample was given a decoction of 2 gr roselle petals every day for seven days. The research instrument used a digital sphygmomanometer, observation sheets, and Standard Operating Procedures. Statistical test using Paired T Test. The control group had an increase in systolic and diastolic mean of 6.3 mmHg and 2.0 mmHg. In the roselle flower group, there was a decrease in the systolic and diastolic mean of 12.64 mmHg and 11.58 mmHg. The difference between the changes in the mean posttest-prettest systolic and diastolic control and roselle groups was 18.94 mmHg and 13.58 mmHg. The bivariate results of the systolic and diastolic pretest-posttest in the roselle flower group obtained p-values ​​of 0,000 and 0,000. Comparison of systolic and diastolic blood pressure in the control group and rosella flowers obtained p-values ​​of 0.000 and 0.000. Rosella flower is effective in reducing systolic and diastolic blood pressure in hypertensive patients.
Keywords: Blood Pressure; Hibiscus Sabdariffa; Hypertension
THE RELATIONSHIP OF SOCIO- ECONOMIC STATUS AND THE OCCURRENCE INJURY OF DIABETES MELLITUS PATIENTS
Authors: Mayawati Desti , Kamal Sodiq , Wahyuningtyas Eka Sakti 
Published: July 2023

Socio-economic status includes a person's lack of education and income which can affect a person's health status. The purpose of this study was to determine whether there is a relationship between socioeconomic status and the incidence of injury in people with Diabetes Mellitus. The method used is a correlation analytic design, with a cross-sectional approach with a sample of 120 respondents. The instrument used was a questionnaire. The data were processed using the Spearman statistical test. The results showed that there was a significant relationship between socioeconomic status and the incidence of injury (p-value = 0.001; r = -0.313). Results of multivariate analysis in research using linear regression that shows that the R result is 0.343. The socioeconomic status regression coefficient on the incidence of injury was 0.185 while the regression coefficient for self-care activities on the incidence of injury was 0.133. A socio-economic status that includes education and income influences a person to carry out self-care management to prevent complications of Diabetes Mellitus, namely Diabetic ulcer.
Keywords: Diabetes Mellitus; Incident Of Injury; Socio-Economic Status
Reduction of copper oxide by formic acid in a narrow gap under various conditions
Authors: Ozawa Naoto , Maruyama Megu , Shibata Masami 
Published: July 2023

Abstract
In this study, the reduction rate of a copper oxide film by formic acid gas was measured under various conditions using a vacuum chamber and ellipsometer. The results revealed that the reduction rate of the oxide film in a narrow gap on the copper plate surface covered by a glass plate was 1.2 times greater than that on the surface of an uncovered copper plate. In addition, the reduction rate determined for a mixture of formic acid gas with a partial pressure of 1000 Pa and N2 gas with a partial pressure of 19 000 Pa was approximately two times lower than that measured for pure formic acid gas supplied at a pressure of 1000 Pa. Meanwhile, increasing the partial pressure of formic acid increased the copper oxide reduction rate. Finally, the reduction rates calculated using a direct simulation Monte Carlo method were in good agreement with the experimental data.
PELATIHAN COMPUTATIONAL THINKING BAGI GURU MI DAN MTs AD DAUD KOTA SAMARINDA
Authors: Qomariah Siti , Rahman Fathur , Wibowo Arista 
Published: July 2023

Computational Thinking (CT) adalah proses berfikir untuk memformulasikan persoalan dan solusinya. Metode pemecahan masalahnya menerapkan teknik dari ilmu komputer (informatika). Penerapan pendekatan computational thinking dalam proses pembelajaran akan memungkinkan siswa untuk membuat hubungan antara materi pelajaran dan kehidupan mereka di luar kelas. Kegiatan Pengabidan masyarakat ini bertujuan untuk mensosialisasikan dan memberikan pelatihan dan pembinaan kepada sekolah terkait metode computational thinking. Hasil yang diharapkan adalah metode computational thinking (CT) ini dapat diintegrasikan ke dalam proses pembelajaran di sekolah, sehingga mendorong siswa untuk berpikir lebih komputasi. Selain itu, diharapkan para guru mampu mempersiapkan siswa untuk berkompetisi di Bebras Challenge Indonesia sebagai kompetisi Computational Thinking. Kegiatan ini terdiri dari pemaparan computational thinking, pembahasan soal menggunakan computational thinking, dan pengenalan Bebras Challenge. Pada kegiatan pengabdian ini peserta mengalami peningkatan pengetahuan mengenai Computational Thinking serta adanya feedback penilaian bagi fasilitator
STRATEGI SOSIALISASI PERDA PENCEGAHAN PERNIKAHAN DINI DI MASA PANDEMI
Authors: Husbuyanti Irma El-mira , Mandini Denda Devi Sarah 
Published: July 2023

Nusa Tenggara Barat (NTB) tercatat sebagai provinsi pertama di Indonesia yang mengesahkan Peraturan Daerah (Perda) yang secara khusus membahas tentang pernikahan anak, melalui Perda Nomor 5 tahun 2021. Hal ini dilatarbelakangi tingginya lonjakan kasus pernikahan dini pada tahun 2020 karena perubahan pola belajar secara daring selama pandemi Covid-19. Penelitian berfokus pada analisa strategi sosialisasi Kabupaten Lombok Timur sebagai salah satu daerah dengan angka pernikahan dini tertinggi di Provinsi NTB selama masa pandemi Covid-19. Penelitian dilaksanakan dengan pendekatan kualitatif dan metode deskriptif. Adapun hasil penelitian menjelaskan strategi sosialisasi peraturan pencegahan pernikahan dini Kabupaten Lombok Timur dilakukan melalui penguatan kelembagaan, serta penanganan kasus dan pembinaan langsung ke masyarakat.
Kata kunci: strategi komunikasi, pandemi Covid-19, pernikahan dini, pernikahan anak, perda pencegahan perkawinan anak.
Present and future about the treatment of hepatitis B virus
Authors: Martínez Amate E , Porcel Martín A 
Published: July 2023

Resumen

La meta del tratamiento del virus B (VHB) es lograr la curación de la infección, algo que con los tratamientos disponibles hoy día, conseguimos en un pequeño porcentaje de pacientes.

Es por ello que, actualmente se aceptan en práctica clínica, otros objetivos secundarios como son: mejorar la supervivencia y la calidad de vida del paciente, impedir el desarrollo de enfermedad hepática y de carcinoma hepatocelular (CHC), a la espera de un tratamiento ideal que consiga la curación funcional del VHB (pérdida sostenida del HbsAg).

Con este objetivo, se han ensayado con distintas estrategias como la combinación de fármacos conocidos o incluso la retirada del tratamiento, sin conseguirse aumentar las tasas de acaloramiento del HbsAg.

Actualmente existen numerosos trabajos de investigación puestos en marcha sobre nuevos tratamientos frente al VHB, los cuales van dirigidos frente a distintas dianas terapéuticas (la entrada celular del virus, su replicación o ensamblaje o frente al sistema inmunitario del huésped) que tiene como objetivo final el aclaramiento del HbsAg.

En los últimos años, han aparecido 2 nuevos fármacos aceptados en práctica clínica para la infección por VHB: TAF (tenofovir alafenamida) nueva formulación de tenofovir indicado fundamentalmente cuando aparecen efectos adversos o en pacientes de riesgo de daño renal y/u óseo; y Bulivertide, un agonista del receptor NTCP, aprobado en 2020 por la Agencia Europea del Medicamento para su indicación como tratamiento en la coinfección VHB-VHD.
Alternatives to Proton Pump Inhibitors for the treatment of gastroesophageal reflux disease and functional dyspepsia
Authors: Grilo Bensusan I 
Published: July 2023

Resumen

Los inhibidores de la bomba de protones (IBP) constituyen un grupo farmacológico ampliamente usado para el tratamiento de la patología esófago-gástrica funcional. Sin embargo, no siempre consiguen el control de los síntomas de dichos procesos, debido a que su fisiopatología no se reduce a la secreción ácida del estómago. Por tanto, el uso exclusivamente de los IBP provocaría en muchos casos un fracaso terapéutico o una respuesta insatisfactoria para el paciente.

En esta revisión se presentarán las alternativas médicas al tratamiento con IBP en la enfermedad por reflujo gastroesofágico y en la dispepsia funcional. Se presentarán aquellos fármacos o productos disponibles en nuestro medio o en otros países, que han demostrado su papel en el tratamiento de dichos procesos. Se hará referencia al contexto en el que pueden ser útiles, la posología, los efectos secundarios más relevantes y las evidencias que recomiendan su uso.

El conocimiento de estas alternativas permitirá un abordaje más completo y con mayor probabilidad de éxito en el tratamiento de estas patologías. Ambas constituyen un motivo de consulta habitual en el ámbito de la Atención Primaria y en la consulta especializada de Aparato Digestivo.
Caecal bascule: an unusual cause of intestinal obstruction.
Authors: Pérez Naranjo P , Pérez Naranjo D 
Published: July 2023

Resumen

La báscula cecal es un tipo infrecuente de vólvulo de ciego que provoca obstrucción intestinal. Su etiología es multifactorial, donde el ciego se pliega en dirección ascendente sobre el colon derecho. Su diagnóstico debe sospecharse siempre que exista dilatación cecal ectópica. La TC es la prueba de imagen de elección, especialmente en pacientes graves.

Se presenta el caso de un hombre de 94 años que acude a Urgencias por cuadro séptico consistente en dolor abdominal generalizado asociado a leucocitosis de casi 20.000/mm3, a la que se le realizó una Tomografía Computarizada con diagnóstico final de obstrucción intestinal por basculación anterior del ciego.
Dysbacteriosis by hafnia alvei: a purpose of a case.
Authors: Bailon Gaona MC , Moreno Barrueco M , Berdugo Hurtado F , Barrientos Delgado A 
Published: July 2023

Resumen

Hafnia alvei, una enterobacteria que forma parte de la microbiota intestinal humana, raras veces crece en coprocultivo y ocasionalmente se considera patógena. Sin embargo, en pacientes con enfermedades crónicas o largos tratamientos con antibiótico, este microorganismo puede generar infecciones invasoras intestinales y extraintestinales a través de un mecanismo de virulencia desconocido. En estos casos, es necesario realizar tratamiento con antibioterapia, siendo de elección el empleo de quinolonas.
MENAKAR EFEKTIVITAS PENYULUH INFORMASI PUBLIK DI WILAYAH 3T
Authors: Hendriani Sri , Kusumadewi Angki 
Published: July 2023

This study seeks to describe the significance of public information extension officers in remote, underprivileged, and frontier areas. Counseling's competency, method, means, content, and outcomes will be discussed in light of Laswell's communication theory. Through surveys of 399 respondents and conversations with 180 selected opinion leaders, information was gathered. The analysis was conducted using a combination of techniques. Results indicated that public information extension workers performed effectively, and the program's efficacy indicated that it was effective as well. Key words: extension officer; competences; communication; information disclosure
The Impact of Star-formation-rate Surface Density on the Electron Density and Ionization Parameter of High-redshift Galaxies*
Authors: Reddy Naveen A. , Sanders Ryan L. , Shapley Alice E. , Topping Michael W. , Kriek Mariska , Coil Alison L. , Mobasher Bahram , Siana Brian , Rezaee Saeed 
Published: July 2023

Abstract
We use the large spectroscopic data set of the MOSFIRE Deep Evolution Field survey to investigate some of the key factors responsible for the elevated ionization parameters (U) inferred for high-redshift galaxies, focusing in particular on the role of star-formation-rate surface density (ΣSFR). Using a sample of 317 galaxies with spectroscopic redshifts z
spec ≃ 1.9–3.7, we construct composite rest-frame optical spectra in bins of ΣSFR and infer electron densities, n
e, using the ratio of the [O ii] λ
λ3727, 3730 doublet. Our analysis suggests a significant (≃3σ) correlation between n
e and ΣSFR. We further find significant correlations between U and ΣSFR for composite spectra of a subsample of 113 galaxies, and for a smaller sample of 25 individual galaxies with inferences of U. The increase in n
e—and possibly also the volume filling factor of dense clumps in H ii regions—with ΣSFR appear to be important factors in explaining the relationship between U and ΣSFR. Further, the increase in n
e and SFR with redshift at a fixed stellar mass can account for most of the redshift evolution of U. These results suggest that the gas density, which sets n
e and the overall level of star formation activity, may play a more important role than metallicity evolution in explaining the elevated ionization parameters of high-redshift galaxies.
Rotation in Event Horizon Telescope Movies
Authors: Conroy Nicholas S. , Bauböck Michi , Dhruv Vedant , Lee Daeyoung , Broderick Avery E. , Chan Chi-kwan , Georgiev Boris , Joshi Abhishek V. , Prather Ben , Gammie Charles F. 
Published: July 2023

Abstract
The Event Horizon Telescope (EHT) has produced images of M87* and Sagittarius A*, and will soon produce time sequences of images, or movies. In anticipation of this, we describe a technique to measure the rotation rate, or pattern speed Ω
p
, from movies using an autocorrelation technique. We validate the technique on Gaussian random field models with a known rotation rate and apply it to a library of synthetic images of Sgr A* based on general relativistic magnetohydrodynamics simulations. We predict that EHT movies will have Ω
p
≈ 1° per GMc
−3, which is of order 15% of the Keplerian orbital frequency in the emitting region. We can plausibly attribute the slow rotation seen in our models to the pattern speed of inward-propagating spiral shocks. We also find that Ω
p
depends strongly on inclination. Application of this technique will enable us to compare future EHT movies with the clockwise rotation of Sgr A* seen in near-infrared flares by GRAVITY. Pattern speed analysis of future EHT observations of M87* and Sgr A* may also provide novel constraints on black hole inclination and spin, as well as an independent measurement of black hole mass.
Measuring What Matters: A Qualitative Study of the Relevance and Clinical Utility of PROMIS Surveys in Systemic Lupus Erythematosus
Authors: Kasturi Shanthini , Ahearn Emily L. , Batterman Adena , Horton Roberta , Kleinman Juliette , Rose-Smith Jillian , LeClair Amy M. , Mandl Lisa A. 
Published: July 2023

ObjectiveTo evaluate the relevance and clinical utility of the Patient-Reported Outcomes Measurement Information System (PROMIS) surveys in patients with systemic lupus erythematosus (SLE).MethodsAdults with SLE receiving routine outpatient care at a tertiary care academic medical center participated in a qualitative study. Patients completed PROMIS computerized adaptive tests (CATs) in 12 selected domains and rated the relevance of each domain to their experience with SLE. Focus groups and interviews were conducted to elucidate the relevance of the PROMIS surveys, identify additional domains of importance, and explore the utility of the surveys in clinical care. Focus group and interview transcripts were coded, and a thematic analysis was performed using an iterative inductive process.ResultsTwenty-eight women and 4 men participated in 4 focus groups and 4 interviews, respectively. Participants endorsed the relevance and comprehensiveness of the selected PROMIS domains in capturing the effect of SLE on their lives. They ranked fatigue, pain interference, sleep disturbance, physical function, and applied cognition abilities as the most salient health-related quality of life (HRQOL) domains. They suggested that the disease-agnostic PROMIS questions holistically captured their lived experience of SLE and its common comorbidities. Participants were enthusiastic about using PROMIS surveys in clinical care and described potential benefits in enabling disease monitoring and management, facilitating communication, and empowering patients.ConclusionPROMIS includes the HRQOL domains that are of most importance to individuals with SLE. Patients suggest that these universal tools can holistically capture the impact of SLE and enhance routine clinical care.
Elaboração e validação de cenários de simulação clínica em hanseníase: comunicação em saúde
Authors: Barbosa Mayara dos Santos , Morais Cyntia Garcia Santiago , Freitas Vitória Maria da Silva , Alvim Lara da Silva , Laurindo Cosme Rezende , Souza Elisa de Oliveira Marsicano de , Coelho Angélica da Conceição Oliveira 
Published: July 2023

Objetivo: construir e validar cenários de simulação clínica para desenvolvimento da habilidade de comunicação em saúde de estudantes/profissionais no atendimento aos pacientes com hanseníase e seus contactantes. Método: desenvolveu-se pesquisa metodológica de novembro de 2020 a dezembro de 2021 em três etapas: construção dos cenários, validação e realização do teste piloto. A construção dos cenários se deu com base na literatura. Participaram da validação dez juízes com expertise em hanseníase e/ou simulação clínica, avaliando os cenários de forma remota por meio de formulários do Google Forms, pelo Índice de Validação de Conteúdo (IVC), no qual um cenário é validado se seu IVC for ≥ 0,80. Os dados foram analisados no software SPSS. O teste piloto foi dividido em: exposição de aula teórica, participação do cenário e debriefing. Participaram cinco estudantes e um profissional da área da saúde. Resultados: Foram elaborados três cenários: suspeição diagnóstica e classificação em hanseníase; vigilância dos contatos e informações sobre aplicação da vacina BCG; consulta na alta por cura, contendo, respectivamente, nove, oito e nove itens, todos com concordância satisfatória (IVC ≥ 0,90). Conclusão: considerou-se validados os cenários da pesquisa, estando disponíveis como novo material didático para fomentar o ensino na área da saúde.
Efeitos de intervenções lúdicas digitais em pacientes oncológicos na pandemia da covid-19: estudo quase-experimental
Authors: Pinto Sandra , Silva Lucimeire Aparecida da , Mata Luciana Regina Ferreira da , Santos Júnior Aires Garcia dos , Moreira Adailson da Silva , Dias Reis Pessalacia Juliana 
Published: July 2023

Objetivo: avaliar o efeito de intervenções lúdicas digitais na qualidade de vida, depressão, ansiedade, estresse e apoio social em pacientes oncológicosna pandemia da Covid-19.Método: estudo quase-experimental, com 15 pacientes de uma organização não governamental brasileira, de agosto de 2020 a outubro de 2021.As intervenções digitais consistiram emcontar histórias, jogos, culinária, expressão artística e corporal. Foram utilizados: questionário sociodemográfico e clínico,questionário de qualidade de vida,escalas de depressão, ansiedade e estresseeapoio social, todos validados em versão brasileira. Os participantesforam avaliados nos tempos: pré-,pós-intervenção1 (após 4 meses) e pós-intervenção2 (após 10 meses).A análise inferencial verificou diferenças entre os tempos utilizando modelos lineares generalizados e testes não paramétricos de Friedman e Nemenyi, considerando-se p≤0,05.Resultados: a percepção da qualidade de vida melhorouna função emocional pós-intervenção2 em relação ao tempo pré-intervenção,com significância estatística (p=0,0020); depressão (p= 0,0106), ansiedade (p=0,0002), estresse (p=0,0032) e apoio emocional, interação social positiva (p<0,0001)melhoraram com significância estatística pós-intervenção1 e pós-intervenção2relacionadas ao tempo pré-intervenção.Conclusão: as intervenções contribuíram para melhorar a qualidade de vida emocional, depressão, ansiedade, estresse, apoio emocional einteração social positiva em pacientes oncológicosna pandemia, podendo ser estimuladasentre esta população.
Comparison of the Prevalence of Type 2 Diabetes Mellitus in Asian Indians Living in the United States and India: Does Location Matter?
Authors: Ganti Akhil A. , Shivaswamy Vijay 
Published: July 2023

Introduction:
Type 2 diabetes mellitus (T2DM) has affected many people worldwide. One population that is greatly affected by T2DM is the Asian Indian population. The relative effects of genetics and environment on the development of diabetes in adults are not completely understood.

Objectives:
We conducted an analysis to determine if location, through the environment and different diets, affects T2DM inheritance in Asian Indians. We hypothesised that the prevalence of T2DM depended on location.

Materials and Methods:
We analysed previously collected data on T2DM in the individual states of India and the U.S. and used this information to compare the prevalence of T2DM in Asian Indians living in these two countries.

Results:
A total of 1,117,465,226 individuals were surveyed in India. Of these, 108,295,674 individuals had T2DM. Similarly, of the 1,704,846 individuals in the US, 298,107 had T2DM. The prevalence of T2DM was 17.49% in Asian Indians living in the US compared to 9.69% for Indians living in India (P < 0.00001). In individuals with similar genetic backgrounds, environmental factors significantly influence the development of T2DM.
Study of FGF21 Levels in Transgender People and its Association with Metabolic Parameters
Authors: Kumbar Lohit , Kiran Baratam Hari , Dharmalingam Mala , Kalra Pramila 
Published: July 2023

Background:
Fibroblast growth factor (FGF21) is a metabolic regulator whose role in humans is unidentified. FGF21 has generated a lot of potential of becoming a therapeutic agent for the management of type 2 diabetes mellitus and dyslipidaemia. The role of FGF21 in gender dysphoria individuals has not been studied.

Objective:
Primary objective was to assess FGF21 levels in transgender individuals and compare with controls and secondary objective was to compare FGF21 levels with lipid and glucose parameters in transgender people.

Results:
Twenty-three transfemales and 21 transmales were included in the study and compared with 44 controls. Height and fasting blood glucose of transfemales was statistically greater than transmales, with no other differences in baseline characteristics. Although FGF21 levels were numerically greater in transfemales (183.50 ± 97.39), it was not statistically significant. FGF21 levels did not vary statistically when compared to controls although it was numerically higher. Univariate analysis was done in transgender patients and FGF21 levels were positively correlated with serum total cholesterol and serum LDL cholesterol in transfemales but not in transmales. Multivariate analysis was also done taking 50th centile and 75th centile of FGF21 levels of controls and was found that only serum total cholesterol and serum LDL positively correlated with FGF21 levels in transfemales with 75th centile as cutoff.

Conclusion:
FGF21 levels correlated positively with serum triglycerides and serum LDL cholesterol in transfemales but not in transmales. Hence, FGF21 levels can be used as a marker for the development of metabolic syndrome in transfemales.