bluuebunny/crossref_metadata_2025_split huggingface dataset:
Architectural concretes for 3D construction printing
Authors: Stoletova (Cherepanova) I. A. , Volodchenko A. A. 
Published: January 2025

Introduction. One of the rising architectural trends of the present time is to increase the comfort and aesthetics of the territories of populated areas through artistic improvement, a significant role in which is given to various types of small architectural forms. The most budgetary and, at the same time, reliable and durable material for them is architectural concrete. The bottleneck in the use of concrete for the manufacture of small architectural forms is the relative difficulty of giving it complex spatial configurations. At the current level of development of concrete work technology, this drawback can be easily overcome through the use of construction 3D printing technology. The aim of the work was to develop effective architectural concrete for the manufacture of small architectural forms using the 3D construction printing method, based on composite binders containing weathered quartzite sandstones as a mineral additive, as one of the types of local energy-efficient raw materials. Materials and methods: The section presents comparative characteristics of weathered and unweathered quartzite sandstones.Results. The data on the dynamics of component grinding; compositions and characteristics of composite binders and fine-grained concretes based on them; results of manufacturing a pilot batch of small architectural forms using the construction printing method are presented.Discussion and conclusions. The description and analysis of the obtained experimental data are presented. The conclusions are formulated in which it is noted that for the organization of the production of modern small architectural forms, the technology of 3D construction printing is used, which allows the implementation of complex various spatial forms of products with any level of individualization without increasing costs. The developed molding mixtures confirmed the high efficiency of using weathered quartzite sandstone as part of a composite binder and technogenic sand. The introduction of the developed materials meets the requirements of energy and resource conservation, since the consumption of Portland cement and non-renewable natural resources is reduced.
Algorithm performance study pulse suppression of auto-oscillation phenomena in the electromechanical system of the electric traction drive in braking mode electric traction drive system in braking mode by methods of simulation modeling
Authors: Klimov A. V. 
Published: January 2025

Research relevance. Modes accompanied by increased sliding of a wheel with negative viscous friction, characterized by reduction of friction force at growth of sliding speed, can arise at the movement of the vehicle. In these cases, a loss of stability may occur, resulting in the excitation of auto-oscillation phenomena in the electromechanical system (road-wheel-mechanical drive-electric motor). The emergence of this process sharply increases the dynamic load of the system, which can lead to its failure or breakdown. As a consequence, the development of suppression methods of auto-oscillation phenomena is considered to be an urgent task.Purpose of the research. Verification of operability and efficiency of the suppression method of auto oscillations in the electromechanical system of wheel drive during braking of the vehicle.Materials and Methods. With the help of Lyapunov’ function analysis for the electromechanical system of wheel drive the suppression method of auto oscillation phenomena is substantiated. The study of the algorithm performance has been carried out with the use of MATLAB Simulink program complex.Research results. The operability and efficiency of the algorithm is proved by methods of simulation mathematical modeling, which allows its further use in the development of traffic control systems. In case of braking of the vehicle equipped with antilock braking system with the function of suppression of auto oscillations on a slippery support base the reduction of amplitudes oscillation of angular velocities of wheels by 80% and braking moments by 96% is observed. When this vehicle is braked on a high adhesion base, the amplitudes are reduced by 98% in angular velocities and 81% in torques. In simulation modeling of vehicle braking dynamics on a support base with low adhesion properties it has also been shown that in these cases the evasive maneuver can be performed, which indicates on the increase in controllability and active safety of the vehicle.Conclusion. The practical value of the study lies in the possibility of using the developed algorithm for suppressing auto oscillations in practical application as part of vehicle control systems. The developed algorithm can be used on vehicles of different classes equipped with individual traction electric drive of driving wheels.
Nexus between Financial Development and Economic Prosperity in Selected Countries of Emerging and Developing Asia
Authors: Budhathoki Prem Bahadur , Bhattarai Ganesh , Dahal Arjun Kumar 
Published: January 2025

Background: The link between financial development and economic growth remains debated in theoretical and empirical research. This research focuses on developing and emerging Asian nations to determine the impact of financial development on economic growth.
Methods: This study took a sample of six member countries from SAARC and BIMSTEC, covering the period from 1990 to 2021, resulting in 192 observations. It employs a descriptive and correlation matrix to examine the distribution and association between predictor and response variables. This study tests the "Finance-led growth theory" using FMOLS and DOLS estimators.
Results: The findings indicate a significant positive effect of financial development on economic growth, assessed through two measures: financial institution development and financial market development. Foreign direct investment has a positive effect on economic growth. In contrast, age dependency, "young," has an adverse and noteworthy impact on economic prosperity. Similarly, export and personal remittance have an unfavorable yet negligible effect on economic growth.
Conclusion: Financial institutions and financial market development positively and significantly affect economic growth in emerging and developing Asia and support the "Finance-led growth theory."
Novelty: This study employs two metrics—financial institution and financial market development—to assess the link between financial development and economic growth and offers ample literature in the context of emerging and developing Asia.
Assessment of Factors Associated with Household Expenditure in Gajuri Rural Municipality, Dhading, Nepal
Authors: Acharya Krishna Prasad 
Published: January 2025

Background: Household expenditure is the total amount of money spent by a household for food, cloth, shelter, education, health, transportation, sanitation, entertainment, and so on. The objective of this study is to identify the significant factors affecting household expenditure in the rural area from the collected 897 primary data from the Gajuri Municipality in December, 2022.
Methods: Stratified random sampling method was used for the data collection and the secondary data was used from the Sahabhagitamulak Gajuri Bikas Guru Yojana, 2074. Ordinary least square regression method was used to analyze the data.
Results: The result of this study shows that the size of the household (β = 0.023, p < 0.001), gender of the household head (β = 0.059, p=0.003), income of the household (β = 0.093, p < 0.001), access to internet in the house (β = -0.191, p < 0.001), and the access to the television in the house (β = -0.090, p < 0.001) were found important in determining household expenditure in this municipality.
Conclusion: From this study, it can be found that the size of the household, gender of the household head, income of the household, access to the internet in the house and access to the television in the house are strongly associated with household expenditure instead of literacy status of household head, remittance receiving status of household, and age of the household head due to the contemporary development and advancement in the society. This study could help policy makers assess factors determining household expenditure and develop plans for Gajuri Rural Municipality.
Novelty: In underdeveloped countries, it is difficult to determine exactly what housing costs are especially in rural areas. This is because uneducated landowners do not account for the consumption of agricultural produce and the expenditure incurred in it.
Benchmark Evaluations, Applications, and Challenges of Large Vision Language Models: A Survey
Authors: Li Zongxia , Wu Xiyang , Du Hongyang , Nghiem Huy , Shi Guangyao 
Published: January 2025

Multimodal Vision Language Models (vlms) have emerged as a transformative technology at the intersection of computer vision and natural language processing, enabling machines to perceive and reason about the world through both visual and textual modalities. For example, models such as CLIP[1], Claude[2], and GPT-4V[3] demonstrate strong reasoning and understanding abilities on visual and textual data and beat classical single modality vision models on zero-shot classification[4]. Despite their rapid advancements in research and growing popularity in applications, a comprehensive survey of existing studies on vlms is notably lacking, particularly for researchers aiming to leverage vlms in their specific domains. To this end, we provide a systematic overview of vlms in the following aspects: [1] model information of the major vlms developed over the past five years (2019-2024); [2] the main architectures and training methods of these vlms; [3] summary and categorization of the popular benchmarks and evaluation metrics of vlms; [4] the applications of vlms including embodied agents, robotics, and video generation; [5] the challenges and issues faced by current vlms such as hallucination, fairness, and safety. Detailed collections including papers and model repository links are listed in https://github.com/zli12321/Awesome-VLM-Papers-And-Models.git.
TINGKAT KEPUASAN KELUARGA PASIEN TENTANG PELAYANAN KEPERAWATAN LANSIA DI POLI GERIATRI
Authors: Wardani Sri , Zulfitri Reni , Woferst Rismadefi 
Published: January 2025

Tujuan: Poliklinik Geriatri merupakan pelayanan medis kepada pasien lanjut usia yang mengalami penurunan fungsi fisik, psikis, sosial, ekonomi, dan lingkungan. Kepuasan pasien dan keluarga adalah indikator penting dari kualitas layanan, mencerminkan bagaimana harapan dan keinginan mereka terpenuhi terhadap pelayanan geriatri. Penelitian ini bertujuan untuk menggambarkan tingkat kepuasan keluarga terhadap pelayanan keperawatan lansia di Poliklinik Geriatri RSUD Arifin Achmad.
Metode: Penelitian ini menggunakan desain penelitian kuantitatif dengan pendekatan observasional deskriptif. Pengumpulan data dilakukan pada bulan Juli 2024 dengan menggunakan kuesioner tingkat kepuasan. Responden penelitian ini adalah keluarga pasien yang dirawat di rumah sakit. Populasi penelitian ini adalah seluruh keluarga pasien di fasilitas tersebut, dengan jumlah sampel sebanyak 97 orang yang dipilih melalui teknik total sampling, di mana seluruh anggota populasi yang memenuhi kriteria inklusi diikutsertakan dalam penelitian. Data yang diperoleh dianalisis menggunakan analisis data univariat, yang bertujuan untuk mendeskripsikan karakteristik tingkat kepuasan keluarga pasien terhadap pelayanan yang diterima.
Hasil: Penelitian menunjukkan bahwa 92,8% keluarga pasien merasa puas dengan pelayanan yang diberikan. Dengan masing-masing persentase perdimensi, 59,8% responden merasa puas dengan pelayanan dimensi tangible, 61,9% responden merasa puas dengan pelayanan reliability, 70,1% responden puas terhadap dimensi responsivness, 74,2% merasa puas pada dimensi assurance dan 58.8% merasa puas dengan dimensi empathy.
Simpulan: Temuan ini menunjukkan bahwa secara umum, pelayanan keperawatan lansia di poliklinik ini memuaskan, namun masih terdapat beberapa aspek yang perlu diperbaiki untuk meningkatkan kepuasan lebih lanjut. Penelitian ini diharapkan dapat memberikan wawasan berharga untuk meningkatkan kualitas pelayanan keperawatan lansia dan menjadi dasar untuk perbaikan berkelanjutan dalam pelayanan untuk memastikan bahwa kebutuhan dan harapan keluarga pasien selalu terpenuhi.
Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders
Authors: Yasir Qasim Almajidi  , Rana Kadum Muslim  , Yaseen T. khalf  
Published: January 2025

ظهرت العلاجات القائمة على الحمض النووي الريبي (RNA) كواحدة من أقوى الخيارات العلاجية المستخدمة لتعديل التعبير الجيني / البروتيني وتحرير الجينات مع إمكانية علاج الأمراض التنكسية العصبية. ومع ذلك ، فإن توصيل الأحماض النووية إلى الجهاز العصبي المركزي (CNS) عن طريق المسار الجهازي ، لا يزال يمثل عقبة رئيسية. للتغلب على هذا المأزق ، تركز هذه المراجعة على الاستراتيجيات الجديدة القائمة على قليل النوكليوتيد بما في ذلك الجسيمات الشحمية ، والأنابيب النانوية الكربونية ، والنقاط الكمومية ، والجسيمات النانوية الدهنية الصلبة ، وحاملات الدهون النانوية ، والجسيمات النانوية البوليمرية ، والسيليكا ميسوبوروس ، والمتشعبات ، والأبتامير ، والأجسام النانوية ، إلخ. تم تصميم هذه الاستراتيجيات للتغلب على هذه الحواجز من خلال مسارات وآليات مختلفة للنقل عبر الحاجز الدموي الدماغي. تقوم الدراسات قبل السريرية والسريرية الجارية بتقييم سلامة وفعالية متعدد نيوكليوتيدات معاكس في العديد من الحالات العصبية الوراثية والمكتسبة. . تقدم المراجعة الحالية تحديثًا للطرق الجديدة والأدلة قبل السريرية والأدلة السريرية وطريق تسليم متعدد نيوكليوتيدات. يوصف أيضًا إدارة متعدد نيوكليوتيدات المعتمدة من قِبل إدارة الأغذية والعقاقير في الاضطرابات العصبية. ستساعد الأدلة الحالية على سلامة وفعالية متعدد نيوكليوتيدات في امراض الدماغ في تحديد الفرص لمجموعة أوسع من الأحماض النووية وتسريع الترجمة السريرية لهذه العلاجات المبتكرة.
Assessment of Zinc Alpha-2 Glycoprotein Level in Gestational Diabetes Woman in Respect to Glycemic Status with and without Treatment
Authors: Bara Nahdh Saleem  , Manal Khalid Abdulridha  , Hind Abdalkhaliq Showman  , Manal Sabbar  
Published: January 2025

الخلفية: سكري الحمل هو حالة مرضية تظهر بين الثلث الثاني والثالث من الحمل. ويتميز بمقاومة الأنسولين الكبيرة الناجمة عن إفراز هرمون المشيمة. تفرز الخلايا الشحمية نوعًا معينًا من البروتين يسمى بروتين سكري الزنك الفا2 (ZAG)، وقد أشارت العديد من الدراسات إلى أن ZAG يشارك في العمليات الفسيولوجية الحاسمة مثل تأييض الجلوكوز. الأهداف: تم تصميم هذه الدراسة لتقييم مستوى ZAG لدى النساء الحوامل المصابات بسكري الحمل على طرائق علاجية مختلفة وما إذا كان يمكن استخدامه كمؤشر حيوي في تشخيص داء سكري الحمل. أيضا لدراسة العلاقة بين ZAG وحالة نسبة السكر في الدم. الطريقة: شمل البحث 76 امرأة حامل (تتراوح أعمارهن بين 18 و40 عامًا)، و22 امرأة حامل تتمتع بصحة جيدة (المجموعة 1)، و30 امرأة حامل تم تشخيصها حديثًا بـسكري الحمل (المجموعة 2)، و24 امرأة حامل مصابة بـسكري الحمل على طرق علاجية مختلفة (المجموعة 3)، في الثلث الثاني أو الثالث من الحمل. ; تم قياس جميع الخصائص الديموغرافية ومؤشرات السكر في الدم. النتيجة: لم تختلف مستويات ZAG في مجموعات الدراسة بشكل كبير عن بعضها البعض (P≥ 0.05)؛ لذلك، أظهرت النساء الحوامل المصابات بـسكري الحمل في المجموعة 2 أعلى مستوى من .ZAG وقد لوحظ تباين كبير في مستويات ZAG بين المجموعات الفرعية من النساء الحوامل المصابات بسكري الحمل المعالجات. أظهرت مجموعة الميتفورمين أدنى مستوى من ZAG (P <0.01) . كانت هناك زيادة كبيرة في نسبة الجلوكوز في الدم أثناء الصيام والهيموجلوبين السكري في مجموعة النساء الحوامل المصابات بسكري الحمل 2 و 3 مقارنة بالنساء الحوامل في المجموعة 1، وفي الوقت نفسه، زيادة طفيفة في مستوى الأنسولين في بلازما الصيام وتقييم نموذج التوازن لمقاومة الأنسولين (HOMA IR) بين المجموعة 2 و 3 مقارنة بالنساء الحوامل من المجموعة 1، وإن لم تكن ذات دلالة إحصائية .(P≥ 0.05) لم يتم العثور على علاقة ذات دلالة إحصائية بين ZAG ومؤشرات نسبة السكر في الدم. الاستنتاج: لم يكن هناك اختلاف ذو دلالة إحصائية في مستوى ZAG بين مجموعات الدراسة (P≥ 0.05)، وبالتالي، أظهرت النساء الحوامل المصابات بسكري الحمل في المجموعة 2 أعلى مستوى. لا يمكن استخدام ZAG كمؤشر في تشخيص داء سكري الحمل.
Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease
Authors: Liu Xian , Yu Qin , Mao Hai-Bo , Hu Jing-Bo , Liu Wei-Hua 
Published: January 2025

Renal ischemia-reperfusion (IR) induces tissue hypoxia, resulting in disrupted energy metabolism and heightened oxidative stress. These factors contribute to tubular cell damage, which is a leading cause of acute kidney injury (AKI) and can progress to chronic kidney disease (CKD). The excessive generation of reactive oxygen species (ROS) plays a crucial role in the pathogenesis of AKI. This study presents the synthesis of curcumin ultra-small coordination polymer (Ru/Cur) nanodots and their application in scavenging ROS in renal tissues. By adding ruthenium ions to a methanol solution containing the natural product curcumin, ultra-small Ru/Cur nanodots were successfully synthesized. To enhance the dispersibility of these nanoparticles in water, polyvinylpyrrolidone (PVP) was used as a growth aid, resulting in highly stable nanodots with sizes smaller than 10 nm. The results indicated that Ru/Cur nanodots effectively eliminated various ROS and demonstrated significant therapeutic effects and biocompatibility in IR-AKI mice, reducing markers of kidney function damage, alleviating renal oxidative stress, and decreasing inflammatory cell infiltration. Ru/Cur nanodots inhibited renal fibrosis by suppressing epithelial-mesenchymal transition and the secretion of transforming growth factor-β1 in the model of IR-AKI to chronic kidney disease (CKD). In summary, our findings confirm that Ru/Cur nanodots mitigate the pathological conditions associated with both AKI and its progression to CKD by reducing IR-induced tubular cell injury.
Characterization and application of fluorescent hydrogel films with superior mechanical properties in detecting iron(Ⅲ) ions and ferroptosis in oral cancer
Authors: Wen Jinxi , Wang Jian , Wang Siqi , Zhou Xingping , Fu You 
Published: January 2025

A one-step hydrothermal method was applied to prepare carbon dots (CDs) with superior fluorescence properties using chitosan as a carbon source. The as-prepared carbon dots were then grafted onto a sodium alginate-gelatin hydrogel film to form a fluorescent hydrogel film (FHGF), emitting at 450 nm under excitation of 350 nm light. In comparison to the CDs, the fluorescence intensity of this film was maintained over 90.0% and the luminescence position remained basically unchanged, caused by the unchanged surface light-emitting structure of the CDs, due to the existence of electrostatic repulsion between the CDs and the hydrogel. Moreover, the tensile-stress of the fluorescent film with 1.0 wt.% of the CDs was increased by 200% to 10.3 Mpa, and the strain was increased from 117% to 153%. The above experimental results are attributed to the hydrogen bonding between the CDs and the sodium alginate-gelatin hydrogel from analyses of the FT-IR spectra. Interestingly, Fe3+ exerted a great quenching effect on this fluorescent film in the concentration range of 0–1.8 μM. The film can be basically used recyclically to detect Fe3+ in solution with a detection limit as low as 0.043 μM. In a word, this work demonstrated an enormous potential of carbon dots in fabricating mechanical and fluorescent properties of the hydrogel and proposed a new detection platform for Fe3+. In view of the promising Fe3+ detection capacity, this hydrogel film can also be applied in oral bacteria surveillance and semi-quantification of ferroptosis in oral cancer.
Generation of bovine decellularized testicular bio-scaffolds as a 3D platform for testis bioengineering
Authors: Di Filippo Francesca , Brevini Tiziana A. L. , Pennarossa Georgia , Gandolfi Fulvio 
Published: January 2025

Accelerating the genetic selection to obtain animals more resilient to climate changes, and with a lower environmental impact, would greatly benefit by a substantial shortening of the generation interval. One way to achieve this goal is to generate male gametes directly from embryos. However, spermatogenesis is a complex biological process that, at present, can be partially reproduced in vitro only in the mouse. The development of reliable 3D in vitro models able to mimic the architecture and the physiological microenvironment of the testis, represents a possible strategy to facilitate ex vivo haploid male gamete generation in domestic species. Here we describe the creation of bovine testicular bio-scaffolds and their successful repopulation in vitro with bovine testicular cells. In particular, bovine testes are subjected to three different decellularization protocols. Cellular compartment removal and extracellular matrix preservation are evaluated. The generated bio-scaffolds are then repopulated with bovine testicular fibroblasts. The results obtained demonstrate that the decellularization protocol involving the use of 0.3% sodium dodecyl sulfate (SDS) for 12 h efficiently eliminates native cells, while preserving intact ECM composition and microstructure. Its subsequent repopulation with bovine fibroblasts demonstrates successful cell homing, colonization and growth, consistent with the scaffold ability to sustain cell adherence and proliferation. Overall, the generated 3D bio-scaffolds may constitute a suitable artificial niche for ex vivo culture of testicular cells and may represent a possible strategy to reproduce spermatogenesis in vitro.
Impact of comorbid constipation on the survival of patients with heart failure: a multicenter, prospective cohort study conducted in Japan
Authors: Ishida Tomoaki , Kawada Kei , Jobu Kohei , Hamada Tomoyuki , Kubo Toru , Okazaki Moemi , Kawai Kazuya , Nakaoka Yoko , Yabe Toshikazu , Furuno Takashi , Yamada Eisuke , Kitaoka Hiroaki , Hamada Yukihiro 
Published: January 2025

BackgroundConstipation frequently affects heart failure patients because of medication side effects and physiological effects of the condition. Although recent speculation suggests that comorbid constipation may affect cardiovascular disease onset and survival rates, this relationship remains unclear. We examined the effect of comorbid constipation on the survival of patients with heart failure.MethodsWe conducted a multicenter prospective cohort study (the Kochi YOSACOI study) of patients hospitalized for acute decompensated heart failure. The influence of comorbid constipation on survival was evaluated using Cox regression analysis with 2-year survival as the index. Patients were divided into two groups based on the presence of comorbid constipation. The patient background was adjusted using propensity score matching, and the evaluation included assessing the 2-year survival and cardiovascular mortality occurrence using the log-rank test.ResultsAmong 1,061 patients hospitalized for acute decompensated heart failure, 715 with complete data (124 with comorbid constipation and 591 without) were analyzed. Comorbid constipation was identified as a risk factor for poorer survival in the Cox regression model (hazard ratio: 1.90, 95% confidence interval: 1.3–2.8, P &lt; 0.001). Propensity score matching included 104 patients in each group. Survival analysis using the log-rank test indicated worse survival (P = 0.023) and higher cardiovascular mortality (P = 0.043) in the comorbid constipation group.ConclusionConstipation can negatively affect the survival of patients with heart failure. Although the causal link between constipation and decreased survival remains unclear, identifying comorbid constipation is essential for identifying heart failure patients at a higher risk of poor outcomes.