bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Kasus Sering Buang Air Kecil pada Ibu Hamil Trimester III dengan Terapy Non Farmakologi di Daerah Aliran Sungai (DAS) Kota Palangka Raya Tahun 2024
Authors: Stefanicia Stefanicia , Indriani Indriani 
Published: January 2025

Latar Belakang : Ketidaknyamanan yang dirasakan ibu hamil pada TM III salah satunya sering buang air kecil, dimana 59% ibu hamil mengeluh sering buang air kecil pada Trimester I , 61% pada Trimester II, dan sekitar 81% pada Trimester III kehamilan (Qomary, 2020). Berdasarkan Jurnal lnvolusi Kebidanan, jumlah ibu hamil yang dengan masalah ketidaknyamanan sering buang air kecil di lndonesia sekitar 50%, jumlah keluhan sering buang air kecil pada ibu hamil yang tidak bisa menahan BAK yaitu sebesar 37,9%. Tujuan :Memberikan Asuhan Kebidanan Kehamilan Pada Asuhan Kebidanan Kehamilan Pada Ny. M Trimester III G1P0A0 Hamil 37 Minggu Dengan Kehamilan Fisiologis di Ruang KIA UPTD Puskesmas Pahandut. Metodologi: Jenis penelitian yang digunakan yaitu secara kualitatif deskriptif dengan metode pendekatan studi kasus. Desain menggunakan observasional lapangan. Metode pengumpulan data dengan cara wawancara, dan analisis dokumentasi asuhan kebidanan. Analisis data diperoleh dari penelitian studi kasus dengan membuat narasi dari hasil observasi dan deskripsi analisis asuhan kebidanan, pengkajian, merumuskan diagnosa, merencanakan, melaksanakan, dan melakukan evaluasi asuhan kebidanan. Penelitian dilakukan pada bulan November 2023. Hasil : Ny. M bersedia untuk mencoba pengobatan alternative komplementer, dengan menjaga personal hygiene khususnya daerah kewanitaan, dan dengan pengobatan non farmakologi, yaitu menganjurkan ibu untuk mencoba ibu untuk melakukan latihan kegel, untuk memperkuat otot – otot dasar panggul, otot vagina, perut. Kontraksikan otot – otot di sekitarnya lubang vagina, saluran kemih, dan anus ( seperti saat menahan kencing), dapat dilakukan pada posisi berbaring atau duduk tahan beberapa saat, lalu lepaskan. Lakukan setidaknya 25 kali pengulangan pada waktu yang berbeda dalam sehari (pagi, siang, dan sore hari).
Pengembangan Buku Ajar Geometri di SD dengan Pendekatan RME Berbasis Simbol Budaya Suku Dayak Ngaju Kalimantan Tengah
Authors: Sari Rospala Hanisah Yukti , Rezki Istighfaris 
Published: January 2025

Integrasi kearifan lokal pada pembelajaran matematika masih jarang dilaksanakan. Selain itu, mayoritas pembelajaran matematika di kelas kurang bermakna dan monoton sehingga siswa merasa bosan dan jenuh ketika belajar matematika. Tujuan dari penelitian ini yaitu: 1) Mengembangkan buku ajar materi geometri di SD dengan pendekatan RME berbasis simbol budaya Suku Dayak Ngaju di KalimantanTengah; 2) Melakukan sosialisasi produk pengembangan buku ajar materi geometri di Sekolah Dasar dengan pendekatan RME berbasis simbol budaya Suku Dayak Ngaju melalui pembelajaran di kelas. Metode penelitian ini yaitu metode Research and Development (RnD) dengan model 4-D. Teknik pengumpulan data menggunakan angket validasi berupa skala Likert untuk mengetahui kelayakan produk yang dikembangkan. Hasil penelitian menunjukkan bahwa: (1) pengembangan buku ajar materi geometri berbasis kearifan lokal suku dayak di SD telah terkategori layak untuk digunakan; (2) Diseminasi produk pengembangan buku ajar materi geometri berbasis kearifan lokal suku dayak dapat menimbulkan kepuasan dalam pembelajaran matematika guru dan siswa SD. Kesimpulan dalam penelitian pengembangan ini sebagai berikut: (1) Pengembangan buku ajar materi geometri berbasis kearifan lokal suku dayak di SD telah terkategori layak untuk digunakan; (2) Diseminasi produk pengembangan buku ajar materi geometri berbasis kearifan lokal suku dayak dapat menimbulkan kepuasan dalam pembelajaran matematika guru dan siswa SD.
Analisis Tingkat Kepuasan Pasien Terhadap Pelayanan Antenatal Care di Praktek Mandiri Bidan Delima Sumatera Barat
Authors: Laila Laila , Safaringga Miranie , Iffah Uliy , Suryafma Feby , Wulandari Tiara , Novelin Putri 
Published: January 2025

Angka Kematian Ibu (AKI) di Indonesia terus meningkat. Kematian ibu disebabkan oleh perdarahan pasca persalinan, pre-eklampsia dan sepsis.. Ketidakpuasan pasien terhadap pelayanan Antenatal care menjadi penyebab tidak langsung dari tingginya angka kematian ibu. Kepuasan pasien terbagi menjadi 5 dimensi yaitu tangible, reliability, responsiveness, assurance, dan empathy. Tujuan dari penelitian ini adalah untuk menganalisis kepuasan pasien terhadap pelayanan antenatal care di Praktek Mandiri Bidan Delima di Wilayah Sumatera Barat. Metode yang digunakan pada penelitian ini adalah metode kombinasi (Mix Methode) dengan model urutan pembuktian (sequential explanatory). Penelitian dilakukan di beberapa Praktek Mandiri Bidan Delima di Wilayah Sumatera Barat pada bulan September-Oktober Tahun 2023. Pengambilan data dilakukan melalui pengisian kuesioner secara online oleh responden. Sampel pada penelitian ini berjumlah 106 responden dengan metode Accidental sampling. Informan pada penelitian kualitatif ini adalah 3 orang ibu hamil yang melakukan ANC dan 3 orang keluarga ibu hamil. Dilakukan analisa data dengan metode triangulasi. Hasil penelitian didapatkan sebagian besar Ibu hamil yang menerima pelayanan Bidan Delima di wilayah Sumatera Barat sangat puas dengan pelayanan ANC yang diberikan. Tingkat kepuasan yang baik menunjukkan mutu pelayanan yang baik. Hasil penelitian kualitatif menunjukkan bahwa pelayanan Bidan Delima sudah baik.
Prosedur Pelayanan dan Ketersediaan Fasilitas dengan Kepuasan Pasien di Puskesmas
Authors: Gusrianti Gusrianti , Ulva Fadillah , Azka Nizwardi 
Published: January 2025

Standar kepuasan pasien di pelayanan kesehatan ditetapkan secara nasional oleh Departemen Kesehatan. Menurut Peraturan Kementrian Kesehatan Republik Indonesia Tahun 2016 tentang Standar Pelayanan Minimal untuk kepuasan pasien yaitu diatas 95%. Bila ditemukan pelayanan kesehatan dengan tingkat kepuasaan pasien berada dibawah 95%, maka dianggap 6 pelayanan kesehatan yang diberikan tidak memenuhi standar minimal atau tidak berkualitas. Tujuan Penelitian ini adalah untuk mengetahui hubungan prosedur pelayanan dan ketersedian fasilitas dengan kepuasan pasien yang mendapat pelayanan kesehatan di Puskesmas. Penelitian ini menggunakan metode kuantitatif dengan desain studi cross sectional. Penelitian dilaksanakan di Kota Padang dengan studi kasus di Puskesmas X. Penelitian dilaksanakan pada bulan Agustus – Desember 2023. Populasi pada penelitian ini adalah pasien yang berkunjung ke Puskesmas X sebanyak 129.199 kunjungan. Sampel didapatkan dengan metode accidental sampling berjumlah 44 responden. Data yang dikumpulkan berupa data primer dengan menggunakan kuesioer. Data dianalisis secara univariat dan bivariat. Berdasarkan hasil penelitian diketahui 54,5% responden tidak puas dalam mendapatkan pelayanan kesehatan, 59,1% responden mengatakan prosedur pelayanan kurang baik, dan 59,1% responden mengatakan ketersediaan fasilitas kurang baik. Berdasarkan uji statistik, terdapat hubungan yang bermakna antara prosedur pelayanan (p-value : 0,0001) dan ketersediaan fasilitas (p-value : 0,008) dengan kepuasan pasien di Puskesmas.
Pendidikan Mitigasi Bencana dan Kesiapsiagaan Anak dalam Menghadapi Gempa Bumi di SDN 09 Berok Nipah
Authors: Maharani Shania , Sari Rebbi Permata , Ikbal Revi Neini , Rahmi Hidayatul 
Published: January 2025

Gempa bumi merupakan bencana alam yang sering kali menimbulkan korban jiwa, terutama pada anak-anak yang rentan akibat kurangnya pemahaman mengenai mitigasi bencana. SDN 09 Berok Nipah berada di garis tepi pantai Kota Padang yang memiliki 72 siswa yang menjadi kelompok rentan terhadap gempa. Tujuan penelitian untuk mengetahui pengaruh pendidikan mitigasi bencana terhadap kesiapsiagaan anak usia sekolah dalam menghadapi gempa bumi di SDN 09 Berok Nipah. Penelitian menggunakan desain quasy eksperimen one grup pretest-postest. Populasi penelitian anak usia sekolah kelas II-V sebanyak 53 siswa. Proses penelitian dilakukan pada bulan Maret-Agustus 2024, teknik pengambilan sampel menggunakan random sampling sebanyak 34 responden. Pengumpulan data dilakukan menggunakan kuesioner pretest dan posttest setelah diberikan penyuluhan. Data dianalisis secara univariat dan bivariat menggunakan uji wilcoxon .Hasil penelitian rata-rata tingkat pengetahuan sebelum diberikan pendidikan mitigasi bencana 52,18, dan rata-rata pengetahuan sesudah diberikan pendidikan mitigasi bencana 91,06 selisih rata-rata pengatahuan 38,9. Ada pengaruh pendidikan mitigasi bencana gempa bumi terhadap kesiapsiagaan (p-0,000) pada anak usia sekolah di SDN 09 Berok Nipah tahun 2024. Kesimpulan : Diharapkan melalui kepala sekolah dan tenaga pengajar dapat memberikan informasi tentang mitigasi gempa dengan melaksanakan penyuluhan kesehatan dan simulasi bencana secara berkala setiap semester agar siswa mendapatkan pengetahuan yang baik.
Effects of CO2 and liquid digestate concentrations on the growth performance and biomass composition of Tetradesmus obliquus and Chlorella vulgaris microalgal strains
Authors: Sánchez-Quintero Ángela , Parsy Aurélien , Adrien Amandine , Spitzer Lea , Jiménez-Lamana Javier , Fernandes Susana C. M. , Beigbeder Jean-Baptiste 
Published: January 2025

This study evaluated the growth performance of Tetradesmus obliquus and Chlorella vulgaris microalgae cultivated in diluted liquid digestate supplemented with CO2, comparing their efficiency to that of a conventional synthetic media. The presence of an initial concentration of ammonium of 125 mg N-NH4+.L-1 combined with the continuous injection of 1% v/v CO2 enhanced the optimal growth responses and bioremediation potential for both strains in 200-mL cultures. In 6-L flat panel reactors, T. obliquus exhibited superior biomass production, achieving a final biomass concentration of 1.29 ± 0.06 g.L-1, while C. vulgaris reached only 0.36 ± 0.02 g.L-1. Both strains effectively contributed to the bioremediation of the digestate-based culture media, with up to 100% of N-NH4+, 50% of COD, and 55% of P-PO43- removals. The high nitrogen levels in the digestate-based medium significantly increased protein content, with 46.21% ± 3.98% dry weight (DW) for T. obliquus and 44.17% ± 2.24% DW for C. vulgaris as compared to the microalgae cultivated in commercial media. Additionally, the metal content of the microalgal biomass was analyzed to assess its potential use as biostimulants in compliance with European regulations. While chromium concentrations slightly exceeded regulatory thresholds in both strains, the levels of other metals remained within permissible limits.
The interplay between sex, lifestyle factors and built environment on 20-year cardiovascular disease incidence; the ATTICA study (2002–2022)
Authors: Sigala Evangelia G. , Chrysohoou Christina , Barkas Fotios , Liberopoulos Evangelos , Sfikakis Petros P. , Faka Antigoni , Tsioufis Costas , Pitsavos Christos , Panagiotakos Demosthenes 
Published: January 2025

Background and aimThis study aims to investigate the role of the built environment in terms of urban-rural disparities in cardiovascular disease (CVD) epidemiology, focusing on middle- and long-term CVD risk assessment. Moreover, this study seeks to explore sex-specific differences in urban and rural settings.MethodsThe ATTICA Study is a prospective study conducted from 2002 onwards. At baseline, a random sample of 3,042 CVD-free adults (49.8% men) were randomly drawn from the population of the Attica region, in Greece, with 78% dwelling in urban and 22% in rural municipalities. Follow-up examinations were performed in 2006, 2012, and 2022. Of the total participants, 1,988 had complete data for CVD assessment in the 20-year follow-up.ResultsThe 10-year and 20-year CVD incidence was 11.8%, 28.0% in rural municipalities and 16.8%, 38.7% in urban municipalities, respectively (ps &lt; 0.05). Unadjusted data analyses revealed significant differences in clinical, laboratory, and lifestyle-related CVD risk factors between urban and rural residents (ps &lt; 0.05). Additionally, sex-based discrepancies in clinical, anthropometric, circulating, and lifestyle risk factors were observed in stratified analyses of urban and rural settings. Multivariate analyses, including generalized structural equation modeling (GSEM), revealed that the impact of the urban built environment on the long-term (20-year) CVD risk is mediated by lifestyle-related risk factors.ConclusionUrban inhabitants exhibit a higher long-term CVD incidence compared to their rural counterparts, which was partially explained by their lifestyle behaviors. Targeted strategic city planning efforts promoting healthier lifestyle-related behaviors at the micro-environment level could potentially mitigate built-environment impacts on CVD health.
Exposure to specific polyfluoroalkyl chemicals is associated with cardiovascular disease in US adults: a population-based study
Authors: Xiao Wenwen , Jian Guojin , Ma Fei , Li Hong , Yang Xiaohong , Zhang Hengyang , Cao Yongping 
Published: January 2025

BackgroundPolyfluoroalkyl chemicals (PFCs) present potential health risks due to their persistence and bioaccumulation. However, there is currently insufficient evidence regarding their impact on cardiovascular disease (CVD). Consequently, it is imperative to investigate the correlation between PFCs and CVD.MethodsThe data was collected from National Health and Nutrition Examination Survey in 2005–2012. Logistic regression models were employed to assess the association between single PFC and CVD. Generalized additive model (GAM) was used for evaluating nonlinear relationships. Subgroup analyses were conducted to explore interaction effects. Bayesian kernel machine regression (BKMR) and weighted quantile sum (WQS) models were used to evaluate the joint effect of PFC exposures on CVD.ResultsIn logistic regression, PFDE, MPAH, and PFUA were positively associated with CVD. In the GAM, there was a significant nonlinear relationship between MPAH and CVD. Subgroup analysis revealed the interaction of gender and race in the effects of PFCs and CVD. PFUA was positively correlated with CVD in males but show no significant difference in females. PFDE was positively associated with CVD among non-Hispanic white individual. The results of BKMR indicated that the impact of mixed PFCs on CVD increased initially and then weakened, showing an overall positive trend. The results of WQS suggested that PFDO contributed most to the effect.ConclusionOur study showed that serum PFDE, MPAH, and PFUA levels were positively correlated with CVD. PUFA was found to interact with gender and race in relation to CVD. A general positive correlation exists between mixed exposure to PFCs and CVD, with PFDO being the most contributory PFC. Our study provided important evidence for probing the impact of PFCs on CVD and laid a foundation for further mechanism research.
Comparative study on blasting simulation vibration reduction and field vibration reduction experiment of adjacent oil pipeline
Authors: Chen Yi , Zhang Ruichong , Liang Lujia , Wang Yi , Chen Jiaozhong , Xie Chengyu 
Published: January 2025

IntroductionYongxing Tunnel No.1’s complex geology near a buried oil pipeline on the Guizhou-Nanning high-speed route poses blasting risks. Prioritizing pipeline safety, efforts focus on minimizing vibration impacts.MethodsResearch uses numerical simulations and field tests to analyze three delay times and three spacing charge materials for vibration reduction.ResultsOptimal delay is 30 ms, yielding a 0.52 cm/s vibration velocity, 20%-29% lower than 28 ms and 32 ms. Soil is the most effective spacer, achieving 0.46 cm/s, 30.30%-22.03% lower than water and air. Field tests align with simulations.DiscussionFindings provide a reference for optimal vibration reduction and safe construction under similar conditions.
Preparation of phosphogypsum ecological concrete and study on its phytogenic properties
Authors: Liu Rongxin , Liu Chunduo , Du Jiang , Wang Cheng , Yuan Yonghui , Zhang Xin 
Published: January 2025

In this study, vegetative eco-concrete was prepared based on electrolytic manganese slag/phosphogypsum composite cementitious material as binder and clayey ceramic grains as aggregate. Based on the conditions of porosity and water-cement ratio, the optimal proportion of phosphogypsum-based eco-concrete was investigated, and concrete specimens with good performance were prepared (14 days compressive strength: 3.49 MPa, permeability coefficient: 1.37, total porosity: 24.5%, Improved compressive strength by 15% and water retention by 20%). The nutrient matrix of vegetative eco-concrete with different phosphogypsum/electrolytic manganese slag ratios was designed and modified, and the vegetative performance of the eco-concrete was investigated using four-season grass, ryegrass, clippings and clover as the grass species. The results showed that the eco-concrete based on phosphogypsum as raw material was rich in nutrients such as nitrogen, phosphorus and potassium, which could meet the requirements of plant growth, Supporting plant growth with a 30% increase in root length and 25% improvement in biomass compared to control concrete. The addition of improvers had a good passivation effect on heavy metals such as As, Cu, Cr, Zn, Sb and Pb in the phytogenic substrate. The adaptability of different grass species to the planting substrate was Four Seasons &gt; ryegrass &gt; shepherd’s purse &gt; clover, alfalfa, dogbane; the application of electrolytic manganese slag substrate had the best performance of planting, and the planting substrate with the application of improver inhibited the growth of plants. The study addresses the challenge of using phosphogypsum as a binder in concrete, which has traditionally faced issues with strength and stability. By optimizing the mix ratio and curing process, we were able to achieve a concrete material that not only performs well mechanically but also supports plant growth.
Streptococcus intermedius promotes synchronous multiple primary lung cancer progression through apoptosis regulation
Authors: Deng Yi , Dong Zhi Xiang , Yang Gao Hua , Krimsky William S. , Tai Yong Hang , Peng Hao , Huang Gui Ting , Xu Jia Xin , Sarkar Saiyad A. , Peng Jun , Qian Kai 
Published: January 2025

BackgroundDysbiosis of the lung microbiome can contribute to the initiation and progression of lung cancer. Synchronous multiple primary lung cancer (sMPLC) is an increasingly recognized subtype of lung cancer characterized by high morbidity, difficulties in early detection, poor prognosis, and substantial clinical challenges. However, the relationship between sMPLC pathogenesis and changes in the lung microbiome remains unclear.MethodsIn this study, 16S rRNA sequencing was performed on clinical samples to analyze lung microbiome composition. Real-time quantitative PCR (qPCR) was used to quantify bacterial abundance in lung tissues. In addition, flow cytometry was conducted to evaluate cell cycle progression and apoptosis in lung tumor cells.ResultsClinical cohort studies demonstrated that sMPLC occurrence is associated with disturbances in the lung microbiome. Notably, Streptococcus intermedius was enriched in the lungs of sMPLC patients compared with non-tumor controls and accumulated preferentially in tumor tissues. S. intermedius shortened the cell cycle and inhibited apoptosis in lung cancer cells. Analyses of oral and gut microbiomes in different patient cohorts revealed a strong correlation between oral microbiome imbalances and lung microbiome composition in sMPLC patients.ConclusionsThese findings characterize the lung microbiota in sMPLC and identify S. intermedius as a potentially influential bacterial strain. This study provides significant new insights into the diagnosis and treatment of sMPLC.
Synergistic defecation effects of Bifidobacterium animalis subsp. lactis BL-99 and fructooligosaccharide by modulating gut microbiota
Authors: Zhang Qi , Zhao Wen , Luo Jie , Shi Shaoqi , Niu Xiaokang , He Jian , Wang Yicheng , Zeng Zhaozhong , Jiang Qiuyue , Fang Bing , Chen Juan , Li Yixuan , Wang Fuqing , He Jingjing , Guo Jie , Zhang Ming , Zhang Liwei , Ge Shaoyang , Hung Wei-Lian , Wang Ran 
Published: January 2025

IntroductionSynbiotics have revealed the possibility of improving constipation through gut microbiota. The synergistic efficacy of Bifidobacterium animalis subsp. lactis BL-99 (BL-99) and fructooligosaccharide (FOS) on constipation have not been investigated.MethodsLoperamide-induced constipated mice model was established to explore the effect of BL-99, FOS, and BL-99+FOS on changes of defecation-related parameters, gut microbiota and metabolites.Results and discussionThe results showed that BL-99, FOS, and BL-99+FOS each alleviated constipation, with the synbiotic showing significant efficacy in the first black stool defecation time, fecal number, fecal weight, and the gastrointestinal transit rate (P &lt; 0.05). Additionally, significant increased in serum 5-HT and IL-10 were observed in the BL-99+FOS group, alongside an increased relative abundance of Lachnospiraceae_NK4A136_group, Blautia, and Clostridium sensu stricto 1, while significantly reducing the relative abundance of Alistipes and Bacteroides. These changes facilitated alterations in short-chain fatty acids (SCFAs) metabolism, and were closely associated with the expression of genes related to the 5-HT pathway and the modulation of serum inflammatory factors. This study provides a theoretical basis for BL-99 and FOS synbiotics to improve constipation by regulating the gut microbiota and metabolites.
Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies
Authors: Wang Gong , Chen Mao , Gao Fei , Guo Meng , Li Maohua , He Qian , Jiang Jiaojin , Huang Cheng , Chen Xiaoyan , Xu Rui 
Published: January 2025

ObjectiveTo investigate the differences of clinical characteristics and treatment outcomes between paraneoplastic neurologic syndrome (PNS) patients with one high-risk antibody and patients with two high-risk antibodies.MethodsWe retrospectively analyzed the data of 51 PNS patients with high-risk antibody. Clinical data were extracted from the patients’ electronic medical records. Clinical presentations, cerebrospinal fluid (CSF) parameters, radiological characteristics and treatment outcomes between patients with one high-risk antibody and patients with two high-risk antibodies were analyzed.Results41 patients with 1 high-risk antibody and 10 patients with 2 high-risk antibodies were enrolled in this study. It was found that psychobehavioral abnormality (OR = 11.327, 95% CI: 1.371 to 93.602, P = 0.024), bowel and bladder dysfunction (OR = 23.537, 95% CI: 1.753 to 316.005, P = 0.017), and total protein of CSF (OR = 61.556, 95% CI: 2.926 to 1294.974, P = 0.008) were risk factors for increased number of high-risk antibodies in PNS. After immunotherapy treatment, Expanded Disability Status Scale (EDSS) scores in PNS patients with 2 high-risk antibodies were higher than that in PNS patients with 1 high-risk antibody (4.8 ± 2.4 vs. 3.0 ± 2.4, p = 0.043). EDSS change analysis also revealed that average EDSS score decreased after treatment in PNS with 1 Ab group while increased in PNS with 2 Abs group (p = 0.032).ConclusionsPsychobehavioral abnormality, bowel and bladder dysfunction, and total protein of CSF were three variables associated with increased number of high-risk antibodies in PNS patients, while increased number of high-risk antibodies might indicate a poor immunotherapy response. Our findings might help to understand the association of PNS patients’ clinical features and high-risk antibodies, as well as to guide clinical practice.