bluuebunny/crossref_metadata_2025_split huggingface dataset:
Positive Emotions Training (PoET) as an Online Intervention to Improve Mental Health: A Feasibility Study
Authors: Niemann Lara , von Gruner Celin , Zhang Xiao Chi , Margraf Jürgen , Totzeck Christina 
Published: March 2023

Abstract
Background: Positive psychology interventions are known to have an impact on mental health as well as on a number of beneficial characteristics like optimism, gratitude and self-efficacy. The Positive Emotions Training (PoET) is one of the first holistic training programs covering eleven positive psychology constructs. The goal of this study was to test PoET’s feasibility in the general population and to assess possible effects on positive and negative mental health factors. Additionally, possible effects on optimism, gratitude, happiness, resilience, and self-efficacy were examined.
Methods: The sample (n = 101) was allocated to PoET (n = 55) or control (n= 46) that did not receive treatment. Participants in the PoET group completed two training sessions (3.5 hours each) that were conducted in an online format with groups of about 30 people. All participants completed positive and negative mental health measures at the beginning of the first training session and at the beginning of the second one as well as 30 days after the second session. Two-factorial repeated measures ANOVAs were conducted to test for possible effects of PoET on mental health.
Results: There were significant effects of PoET on depression and anxiety symptoms as well as on optimism. Non-significant, but descriptive changes were found for positive mental health scores, stress, gratitude, happiness, resilience, and self-efficacy. There were no significant effects for the control group.
Conclusions: Results indicate that PoET is an applicable intervention for improving mental health in the general population.
Trial registration: Retrospectively registered at ClinicalTrials.gov on 21/02/2023 (Identifier/Trial registration number: NCT05737251)
Serum lipid reference values recommended during a twin pregnancy and evaluating its association with perinatal outcomes
Authors: Huang Jiaqi , Gong Xiaoli , Li Jiaxin , Wu Tianchen , Shi Huifeng , Li Xiaona , Yang Jing , Wei Yuan , Zhao Yangyu , Wang Xueju , Meng Xinlu 
Published: March 2023

Abstract
Background: Maternal lipid metabolism fluctuations have been shown to increase the risk of adverse pregnancy outcomes. However, there is no consensus over what constitutes normal maternal lipid values during twin pregnancy. Therefore, the aim of this study was to establish a serum lipid reference range for a twin pregnancy.
Methods: A retrospective survey was conducted, from 2011 to 2021, at the Peking University Third Hospital. A total of 881 twin pregnancies, with lipid data from early and middle pregnancies, were included. After excluding those with adverse pregnancy outcomes, we performed a descriptive analysis of total cholesterol (TC), triglycerides (TG), high-density lipid cholesterol (HDL-C), and low-density lipid cholesterol (LDL-C) levels, using the mean and standard deviation to determine appropriate percentiles. We later determined the lipid reference range in early and middle pregnancy based on the initial results. We evaluated Inappropriate lipid levels associations with pregnancy outcomes, including gestational diabetes, pregnancy-induced hypertension, small for gestational age.
Results: (1) Serum levels of TC, TG, LDL-C, and HDL-C increased significantly from early to late pregnancy, where the greatest increase was observed in TG. (2) Based on the results, we recommend that TC, TG, and LDL-C serum reference values during early and middle pregnancy should be less than the 95th percentile. On the other hand, HDL-C should be greater than the 5th percentile. During early pregnancy, the values recommended are TC＜5.31 mmol/L, TG＜2.25 mmol/L, HDL＞1.02 mmol/L and LDL＜3.27 mmol/L, and those during middle pregnancy are TC＜8.74 mmol/L, TG＜4.89 mmol/L, HDL＞1.25 mmol/L and LDL＜5.49 mmol/L, while the values during late pregnancy are TC＜9.11 mmol/L, TG＜6.70 mmol/L, HDL＞1.10 mmol/L and LDL＜5.81 mmol/L. Higher levels of blood lipids were associated with GDM, PE, SGA.
Conclusions: We suggested a reference ranges for blood lipids during the twin pregnancy in a Chinese population. The reference ranges recommended by this study can be used to identify women with twin pregnancies using unfavorable lipid values. Higher levels of blood lipids were associated with adverse pregnancy outcomes.
Sliding Mode Observer Based Tracking Control for Input Delay Hypersonic Flight Vehicles with Unmeasurable Flexible Dynamics1
Authors: Hu Xiaoxiang , Xiao Bing , Hu Changhua 
Published: March 2023

Abstract
This paper proposes a sliding mode observer (SMO) based control design method for hypersonic flight vehicle (HFV). The flexible states of HFV are assumed to be unmeasurable with considering the measurement difficulties. Then a SMO is designed to estimated them. What is more, the measuring devices are assumed to be suffering from disturbance, then the SMO should not only guarantee the estimation error stable, but also reduce the influence of external disturbances. What’s worse, the input of HFV is suffering from input delay, which brings more difficulties to the controller design. By state transformation,input delay model of HFV is transformed into a delay free model,then a SMO based robust controller is proposed for HFV based on the stable inversion controller design strategy. Numeral simulation results are proposed for the validation of the presented method in the final.
PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, imposes a pH-dependent fitness cost in Escherichia coli as a consequence of promiscuous activity
Authors: Dorrazehi Gol Mohammad , Winkle Matthias , Stroobant Vincent , Degand Hervé , Evrard Damien , Desguin Benoît , Morsomme Pierre , Biboy Jacob , Gray Joe , Vollmer Waldemar , Soumillion Patrice 
Published: March 2023

Abstract
Penicillin binding proteins (PBPs) are involved in biosynthesis, remodeling and recycling of peptidoglycan (PG) in bacteria. PBP-A from Thermosynechococcus elongatus belongs to a cyanobacterial family of enzymes sharing close structural and phylogenetic proximity to class A beta-lactamases. With the aim of converting PBP-A into a beta-lactamase, we expressed the enzyme in the periplasm of Escherichia coli but failed in directed evolution experiments and observed growth defect associated with the enzyme activity. To further explore the molecular origins of the fitness cost, we decided to characterize deeper the activity of PBP-A both in vitro and in vivo. We found that PBP-A is an enzyme endowed with DD-carboxypeptidase and DD-endopeptidase activities, featuring high specificity towards muropeptides amidated on the D-iso-glutamyl residue. We also show that its promiscuous activity on non-amidated peptidoglycan deteriorates E. coli’s envelope and generates the fitness cost, which is much higher under acidic conditions where substrate discrimination is mitigated. Besides expanding our knowledge on the biochemical activity of PBP-A, this work also highlights how promiscuity may hinder rather than promote enzyme evolution in nature or in the laboratory.
Nonphotochemical generation of Singlet oxygen in pollutant remediation: A mini-review on the degradation pathway based on mass spectrometry and DFT calculations
Authors: Reyaroth Manoj , Aravind Usha , Boczkaj Grzegorz , Aravindakumar Charuvila T 
Published: March 2023

Abstract
The degradation of pollutants by a non-radical pathway involving singlet oxygen (1O2) is a hot topic in persulfate-based advanced water treatment processes (PS-AOPs). The selective reaction of 1O2 with organic pollutants resulting the evolution of different intermediate products. While these products are identified by mass spectrometry (MS) techniques, predicting a proper degradation mechanism in 1O2 -based process is still challenging. Hence, we review the possible degradation pathways of organic contaminants in 1O2-mediated oxidation with the support of density functional theory (DFT). The Fukui function (FF, f-, f+, and f0), and HOMO–LUMO energy obtained using DFT were used to identify the active site in the molecule and the degradation mechanism, respectively. Electrophilic addition, outer sphere type single electron transfer (SET), and addition to the hetero atoms are the key mechanisms involved in the degradation of organic contaminants by 1O2. Since the environmental matrices contain several contaminants, it is difficult to experiment with all the contaminants to identify their intermediate products. Therefore, the DFT studies are useful for predicting the intermediate compounds during the oxidative removal of the contaminants, especially for complex composition wastewater.
Taurine supplementation decreases fat accumulation by suppressing FAS and enhancing ATGL
Authors: Geng Xueying , Feng Yafang , Yu Congcong , Yao Yuyang , Chen Wen , Guo Junxia , Zhang Yanzhen , Zhang Jing , Mi Shengquan 
Published: March 2023

Abstract
The effect of taurine on obese rats was studied. Methods: taurine was added to drinking water and given to animals for 21 weeks. ATGL (adipose triglyceride lipase) inhibitor was injected for one week. The results showed that taurine could significantly reduce the body weight and body fat content of fat rats, reduce the levels of the serum TG, TC and LDL-C, increase the level of HDL-C, reduce the lipid deposition in the liver and the aortic arch, decrease the expression of FAS (fatty acid synthase) and increase the expression of ATGL. In addition, in the case of taurine intake, atglistatin (ATGL inhibitor) didn’t affect the expression of FAS and ATGL. Conclusion: Taurine can reduce fat deposition induced by high-fat diet in SD rats, which may be related to reducing FAS content and increasing ATGL content. Taurine does not completely regulate the expression of FAS and ATGL through the ATGL pathway.
Evaluation of optimum classification measures used to define textbook outcome among patients undergoing curative-intent resection of gastric cancer
Authors: Bobrzynski Lukasz , Sędłak Katarzyna , Rawicz-Pruszyński Karol , Kołodziejczyk Piotr , Szczepanik Antoni , Polkowski Wojciech , Richter Piotr , Sierzega Marek 
Published: March 2023

Abstract
Background: Textbook outcome (TO) is a composite measure reflecting various aspects of services provided to patients with solid malignancies. We sought to evaluate the importance of various TO components previously proposed for gastric cancer.
Methods: Prospectively maintained electronic databases of 1,743 patients treated in two academic surgical centres were reviewed. Six candidate definitions of TO were evaluated based on their ability to accurately predict patients’ prognosis by Cox proportional hazards modelling.
Results: TO definition combining 10 measures corresponding to complete tumour resection with an uneventful postoperative course showed the best goodness of fit by achieving the lowest values of Akaike (AIC) and Bayesian (BIC) information criteria and the best predictive performance based on the highest value of c-index. The overall median survival was significantly longer for patients with than without textbook outcome (69.0 vs 20.1 months, P<0.001). TO maintained its prognostic value in a multivariate model controlling for age, sex, comorbidities, treatment, and tumour related variables and was associated with a 39% lower risk of death (HR 0.61, 95%CI 0.51 – 0.73, P<0.001). Nine variables identified as predictors of TO were used to develop a nomogram showing very good correlation between the predicted and actual probability of achieving TO. The AUC of ROC obtained from the nomogram was 0.752 (95% CI 0.727 to 0.781).
Conclusions: A uniform definition of textbook outcome provides clinically relevant prognostic information and could be used in quality improvement programs for gastric cancer patients.
Image encryption algorithm based on the Matryoshka transform and modular-inverse matrix
Authors: Zhang Xiaoqiang , Zhang Xueheng 
Published: March 2023

Abstract
The transmission of digital image in Internet is convenient, but at the same time the great risk of information leakage is existed. To meet the requirements of image content security and real-time communication, we propose an image encryption algorithm based on the Matryoshka transform and modular-inverse matrix. Firstly, a new Matryoshka transform is designed to scramble the original image; secondly, the global chaotic exclusive or operation is performed on the scrambled image, and the diffused result is converted into an image block set; thirdly, the chaotic sequence is used to generate a set of modular odd matrix, and the set of the modular-inverse matrix is calculated; finally, the matrix operation of modular multiplication is performed on the image block set and the modular-inverse matrix set to generate the encrypted image. Meanwhile, the sender passes the secret keys to the recipient using Diffie-Hellman over the elliptic curve. Experimental results and algorithm analyses show that the proposed algorithm has the excellent encryption effect and the strong ability to resist common attacks. Therefore, the proposed algorithm can be applied to the image transmission under the network platform with strong security, desirable encryption effect and high efficiency.
Post-cardiac Injury Syndrome Occurred Two Months after Permanent Dual-chamber Pacemaker Implantation
Authors: Zhang Ruiqi , Liu Meilin , Du Jiali 
Published: March 2023

Abstract
Background: Post cardiac injury syndrome (PCIS) is characterized by the development of pericarditis with or without pericardial effusion due to a recent cardiac injury. The relatively low incidence makes diagnosis of PCIS after implantation of a pacemaker easily be overlooked or underestimated. This report describes one typical case of PCIS.
Case presentation: We present a case report of a 94-year-old male with a history of sick sinus syndrome managed with a dual-chamber pacemaker who presented with PCIS after two months of pacemaker implantation. He gradually developed chest discomfort, weakness, tachycardia and paroxysmal nocturnal dyspnea and cardiac tamponade after two months of pacemaker. Post-cardiac injury syndrome related to dual-chamber pacemaker implantation was considered based on exclusion of other possible causes of pericarditis. His therapy was drainage of pericardial fluid and managed with a combination of colchicine and support therapy. He was placed on long-term colchicine therapy to prevent any recurrences.
Conclusion: This case illustrated that PCIS can occur after minor myocardial injury, and that the possibility of PCIS should be considered if there is a history of possible cardiac insult.
Growth control of Marchantia polymorpha gemmae using nonthermal plasma irradiation
Authors: Tsuboyama Shoko , Okumura Takamasa , Attri Pankaj , Koga Kazunori , Shiratani Masaharu , Kuchitsu Kazuyuki 
Published: March 2023

Abstract
Several studies have documented that treatment by cold atmospheric pressure plasma (CAP) on plants foster seed germination and growth in recent years. However, the molecular processes that underlie the action of CAP on the seeds and plants remain mostly enigmatic. The effects of CAP on seeds could significantly differ depending on their status, thus obstructing detailed molecular analyses. We here introduce gemmae of Marchantia polymorpha, a basal liverwort, as a novel model plant material suitable for CAP research. Treating the gemmae with CAP for a constant time interval at low power resulted in consistent growth enhancement, while growth inhibition at higher power in a dose-dependent manner. These results distinctly demonstrate that CAP irradiation can positively and negatively regulate plant growth depending on the plasma intensity of irradiation, offering a suitable experimental system for understanding the molecular mechanisms underlying the action of CAP in plants.
Amorphous nanoparticles: the essence of clay
Authors: Tsukimura Katsuhiro , Manpuku Kazuko , Miyoshi Youko , Suzuki Masaya , Takagi Tetsuich , Wada Shin-ichi 
Published: March 2023

Abstract
Clay research focuses on phyllosilicate clay minerals such as kaolinite and smectite because these phyllosilicate minerals are considered the most important substance in clay. On the other hand, amorphous nanoparticles are largely ignored because they are thought to be absent in most clay and to have no effect on clay properties. However, a recent study by small angle x-ray scattering has revealed that large amounts of amorphous nanoparticles are present in clay and that these amorphous nanoparticles influence some of the important properties of clay. Another study showed that plasticity, the most important property of clay, is a linear function of the specific surface area. In this study, we have shown that the specific surface area is a linear function of the weight percent of amorphous nanoparticles. Therefore, we can conclude that plasticity is a linear function of the weight percent of amorphous nanoparticles. This indicates that the substance imparting plasticity is not phyllosilicate clay minerals but amorphous nanoparticles, which shows that the essence of clay is amorphous nanoparticles.
Understanding Changes in Heat Waves, Droughts, and Compound Events in Yangtze River Valley and the Corresponding Atmospheric Circulation Patterns
Authors: Qian Zhonghua , Sun Yingxiao , ma qianrong , Gu Yu , Taichen  , Feng Prof 
Published: March 2023

Abstract
Heat waves, droughts, and compound drought and heat waves (CDHWs) have received extensive attention because of their disastrous impacts on agriculture, ecosystems, human health, and society. Here, we computed the heat wave magnitude index (HWMI), drought magnitude index (DMI), and compound drought and heat wave magnitude index (CDHMI) for Yangtze River Valley (YRV) from July to August during 1961–2022. We compared the large-scale atmospheric circulation characteristics of different extreme events based on these indexes. The results show that the positive center with sink motion in East Asia provides a favorable circulation background for heat wave events. Drought events are mainly affected by the zonal wave train dominated by a significant negative anomaly in Siberia and a high-pressure anomaly upstream, and anticyclonic water vapor with strong divergence over the Yangtze River basin. During CDHW events, both anomalous systems that affect heat waves and droughts appear and strengthen simultaneously. Specifically, the positive anomaly center in YRV expands abnormally, and the " +-+" wave train over the northern 50°N region of East Asia becomes more obvious. Therefore, the positive anomaly and water vapor anomaly brought by the two circulation patterns at different latitudes are superimposed over the YRV, leading to severe CDHWs. At the same time, the warm positive eddy center and cold negative eddy center in high latitudes exhibit more stable positive pressure features, which are conducive to the persistent development and strengthening of CDHWs. In addition, the anomalous warm sea surface temperature in western Pacific moderating the favorable circulation patterns may also promote the occurrence of CDHWs in the YRV, which is demonstrated by model simulation.
The rotation of Phallus impudicus benefits the microenvironment via improving the soil microbial structure and soil properties
Authors: Yanhong Wang , Jiao Xu , Qingsong Yuan , Lanping Guo , Chenghong Xiao , Changgui Yang , Liangyuan Li , Weike Jiang , Tao Zhou 
Published: March 2023

Abstract
Backgroud: Rhizosphere microbiome play vital roles in soil nutrient cylcling and plant growth, their diversity and composition are commonly influenced by soil management systems. Currently, however, the specific dynamic of microbial community in cultivation of Gastrodia elata and rotation of Phallus impudicus remains unknown. To narrow this knowledge gap, soil physicochemical properties and soil microbial community in the rhizosphere soil of G. elatacultivation and rotation of P. impudicus management were analyzed and compared.
Results: The results revealed that the cultivation of G. elata and rotation of P. impudicus both increased the diversity, complexity, and stability of the soil microbiome structure and reshaped the soil microbiota composition. In addition, the cultivation of P. impudicus reversed the G. elata-induced decrease in soil pH and nutrient levels, increased soil humification and improved humus composition. The RDA result indicated that the soil microbial community strongly correlates with soil pH and exchangeable Ca/Mg ratio, indicating that soil nutrient levels play dominant roles in soil microbial community improvement in this rotation management system.
Conclusions: Our findings provide insights into microbial community assembly and soil physicochemical properties in cultivation of G. elata and rotation of P. impudicus, rotation affected soil microorganisms mainly through changes in soil nutrient profile and might have potential benefits in next growing season. In addition, our results highlight the importance of rotaion management during artificial cultivation of traditional Chinese medicine for sustainable development.
Cerebral regional and network abnormalities in HIV-infected with neurocognitive impairments: An fMRI study
Authors: Chen Pan-pan , Wei Xiang-yu , Tao Larissa , Xin Xin , Xiao Shaotan , He Na 
Published: March 2023

Abstract
Although the combination antiretroviral treatment (cART) has considerably lowered the risk of HIV associated dementia (HAD), the incidence of neurocognitive impairments(NCI) have not decreased likely due to the insidious and slow progressive nature of HIV infection. Recent studies show that the rest state functional magnetic resonance imaging (rs-fMRI) is a prominent technique in helping the non-invasive analysis of neucognitive impairment. Our study is to explore the neuroimaging characteristics among people living with HIV(PLW-HIV) with or without NCI in terms of cerebral regional and neural network by rs-fMRI, based on the hypothesis that HIV patients with and without NCI have independent brain imaging characteristics. 33 HIV subjects with NCI and 33 HIV subjects without NCI, classified into HIV-NCI group and HIV-control group respectively according to Mini-Mental State Examination(MMSE) results. The fraction amplitude of low-frequency fluctuation (fALFF) and functional connectivity (FC) were calculated to characterize the cerebral regional and neural network alterations. Finally, the correlation among fALFF/FC values in certain cerebral regions and clinical characteristics were calculated. Compared to the HIV-control group, the fALFF values of bilateral calcarine gyrus, bilateral superior occipital gyrus, left middle occipital gyrus, left cuneus in the HIV-NCI group were increased. The FC values between right superior occipital gyrus and right olfactory cortex, bilateral gyrus rectus, right orbital part of middle frontal gyrus in the HIV-NCI group were increased. The FC values between left hippocampus and bilateral medial prefrontal gyrus, bilateral superior frontal gyrus were decreased. The fALFF values of left cuneus in both two groups was negatively correlated with international HIV dementia scale scores (IHDS) (R=-0.255, P=0.037) ; The fALFF values of left calcarine gyrus in both two groups was negatively correlated with MMSE scores (R=-0.316, P=0.009) ; The FC values between right superior occipital gyrus and right olfactory cortex (R=-0.396, P=0.001) in both two groups was negatively correlated with MMSE scores. Our study showed that the abnormal fMRI patterns in specific brain regions of the occipital cortex, while the defects in brain network mostly associated with prefrontal cortex, were associated with HIV-related cognitive impairment. The variation of fALFF and FC in given brain regions can be used to distinguish HIV subjects with and without cognitive impairment.