bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Terapi Murottal Al-Qur'an Terhadap Penurunan Intensitas Nyeri Dan Tingkat Kecemasan Pada Ibu Bersalin Multipara Kala I Fase Aktif
Authors: Yuliana Fitri , Aulya Yenny , Widowati Retno 
Published: May 2023

Nyeri persalinan merupakan suatu kondisi fisiologis yang mulai timbul pada persalinan kala I fase aktif dan makin lama nyeri yang dirasakan akan bertambah kuat. Kontraksi uterus merupakan salah satu yang mengakibatkan nyeri. Kecemasan dan rasa nyeri merupakan masalah yang alamiah dalam menghadapi persalinan. Murottal Al-qur’an merupakan salah satu metode yang memiliki pengaruh positif bagi pendengarnya. Tujuan penelitian ini untuk mengetahui pengaruh terapi murottal Al-qur’an terhadap penurunan intensitas nyeri dan tingkat kecemasan pada ibu bersalin multipara kala I fase aktif. Penelitian ini menggunakan metode quasi experimen dengan rancangan one grup pre-test post-tets design pada 20 ibu bersalin sebagai responden. Terapi murottal Al-qur’an berupa surat Ar-rahmaan diperdengarkan selama 30 menit. Instrument penelitian menggunakan alat ukur Numerik Rating Scale (NRS) dan Hamilton Anxiety Rating Scale (HARS). Analisis data menggunakan paired sample t-test dengan nilai ?= 0,05. Hasil penelitian menunjukan rata-rata skor intensitas nyeri sebelum diberikan terapi murottal Al-qur’an adalah 7,10 setelah diberikan adalah 4,75. Rata-rata skor kecemasan sebelum diberikan terapi Murottal Al-qur’an adalah 22,20 setelah diberikan adalah 12,75. Hasil paired sample t-test menghasilkan nilai signifikan (2-tailed) 0,000. Simpulan pada penelitian ini adalah terdapat perbedaan signifikan skor penurunan rata-rata intensitas nyeri dan tingkat kecemasan ibu sebelum dan setelah dilakukan terapi murottal Al-qur’an. Diharapkan bidan dapat mengedukasi terapi murottal Al-qur’an kepada ibu bersalin, suami, atau keluarga untuk menurunkan intensitas nyeri dan tingkat kecemasan.
Kata kunci: Murottal Al-qur’an, Nyeri, Kecemasan, Persalinan.
Gambaran Kebutuhan Seksual dan Coping Seksual di Lembaga Pemasyarakan Kerobokan Denpasar
Authors: Dewa Ayu Lingga Adi Sawitri  
Published: May 2023

Lembaga pemasyarakatan merupakan tempat para kaum pria dan wanita terpisah. kehidupan di lembaga pemasyarakatan dengan kebebasan yang serba terbatas, terutama dalam hal penyaluran kebutuhan seksual. Tujuan penelitian ini adalah untuk mengetahui persepsi warga binaan tentang kebutuhan seksual dan coping di Lapas Kerobokan Denpasar. Penelitian ini merupakan kualitatif deskriptif, data yang diperoleh melalui wawancara dengan empat (4) informan. Hasil penelitian menunjukkan bahwa responden selama berada di lapas Kerobokan Denpasar menerima keadaan, berlapang dada, berkomunikasi. Untuk mengalihkan kebutuhan seksual saat di lapas, responden melakukan metode problem focused coping dan problem focused coping emotion, dan tidak ada yang menerapkan maladaptive coping
Time-series prediction and detection of potential pathogens in bloodstream infection using mcfDNA sequencing
Authors: Cao Yinghao , Jiang Tingting , Lin Yanfeng , Fang Xiaofeng , Ding Peipei , Song Hongbin , Li Peng , Li Yanjun 
Published: May 2023

IntroductionNext-generation sequencing of microbial cell free DNA (mcfDNA-seq) has emerged as a promising diagnostic method for blood stream infection (BSI) and offers the potential to detect pathogens before blood culture. However, its application is limited by a lack of clinical validation.MethodsWe conducted sequential mcfDNA-seq on blood samples from ICU participants at high risk of BSI due to pneumonia, or intravascular catheterization; and explored whether mcfDNA-seq could diagnose and detect pathogens in advance of blood culture positivity. Blood culture results were used as evaluation criteria.ResultsA total of 111 blood samples were collected during the seven days preceding and on the day of onset of 16 BSI episodes from 13 participants. The diagnostic and total predictive sensitivity of mcfDNA-seq were 90% and 87.5%, respectively. The proportion of pathogenic bacteria was relatively high in terms of both diagnosis and prediction. The reads per million of etiologic agents trended upwards in the days approaching the onset of BSI.DiscussionOur work found that mcfDNA-seq has high diagnostic sensitivity and could be used to identify pathogens before the onset of BSI, which could help expand the clinical application of mcfDNA-seq.
Elevated pulse pressure and cardiovascular risk associated in Spanish population attended in primary care: IBERICAN study
Authors: Moyá-Amengual Ana , Ruiz-García Antonio , Pallarés-Carratalá Vicente , Serrano-Cumplido Adalberto , Prieto-Díaz Miguel Ángel , Segura-Fragoso Antonio , Cinza-Sanjurjo Sergio ,   the researchers of the IBERICAN study
Published: May 2023

IntroductionElevated pulse pressure (ePP) is an independent marker of cardiovascular risk (CVR) in people older than 60, and a functional marker of subclinical target organ damage (sTOD) which can predict cardiovascular events in patients with hypertension (HTN), regardless of sTOD.ObjectiveTo evaluate the prevalence of ePP in adult population seen in primary care and its association with other vascular risk factors, sTOD and with cardiovascular disease (CVD).Materials and methodsObservational multicentre study conducted in Spain (8,066 patients, 54.5% women) from the prospective cohort study IBERICAN recruited in Primary Care. Pulse pressure (PP) was defined as the difference between the systolic blood pressure (SBP) and the diastolic blood pressure (DBP) ≥60 mmHg. Adjusted (for age and sex) ePP prevalence were determined. Bivariate and multivariate analyses of the possible variables associated with ePP were carried out.ResultsThe mean of PP was 52.35 mmHg, and was significantly higher (p &lt; 0.001) in patients with HTN (56.58 vs. 48.45 mmHg) The prevalence of ePP adjusted for age and sex was 23.54% (25.40% men vs. 21.75% women; p &lt; 0.0001). The ePP prevalence rates increased linearly with age (R2 = 0.979) and were significantly more frequent in population aged ≥65 than in population aged &lt;65 (45.47% vs. 20.98%; p &lt; 0.001). HTN, left ventricular hypertrophy, low estimated glomerular filtration rate, alcohol consumption, abdominal obesity, and CVD were independently associated with ePP. 66.27% of patients with ePP had a high or very high CVR, as compared with 36.57% of patients without ePP (OR: 3.41 [95% CI 3.08–3.77]).ConclusionsThe ePP was present in a quarter of our sample, and it was increased with the age. Also, the ePP was more frequent in men, patients with HTN, other TOD (as left ventricular hypertrophy or low estimated glomerular filtration rate) and CVD; because of this, the ePP was associated a higher cardiovascular risk. In our opinion, the ePP is an importer risk marker and its early identification lets to improve better diagnostic and therapeutic management.
The latent category of resilience and its relationship with the mental health and coping styles of medical students
Authors: Song Jiang-Yan , Gao Ya-Qin , Li Hui-Ping , Gao Jie , Li Jia-Xin , Bi Qing-quan , Li Shu-Mei , Ye Yun 
Published: May 2023

BackgroundMedical students suffer more pressure due to various reasons and their mental health problems get more attention. Resilience is a positive psychological perspective to explore the medical students’ mental health and coping style problems. This study focuses on the medical students in school and uses the method of latent category analysis (LCA) to analyze the classification characteristics of their resilience. Therefore, the study aims to help psychological educators in medical colleges to develop positive mental health education strategies for medical students.ObjectiveTo explore the potential categories of resilience of medical students and the relationship between these categories and mental health and coping style.MethodsA total of 1,457 medical students from four medical colleges in Anhui Province were selected as the research subjects by a convenience sampling method. A general information questionnaire, the Connor-Davidson Resilience Scale (CD-RISC), Kessler 10 and the Simplified Coping Style Questionnaire (SCSQ) were used to investigate; SPSS 25.0 and Mplus 7 software were used for basic analysis and latent category exploration.Expected resultsThe medical students were divided into three potential categories of mental resilience: the low resilience group, moderate resilience self-improvement group and high resilience tough group. The optimism dimension level of the three categories was low. There were statistically significant differences in the distribution of resilience among medical students, such as gender, source of students, and paternal and maternal education level. There were significant differences in the mental health, positive coping style and negative coping style scores among the three categories. Female medical students with low parental education levels have a lower level of resilience. Logistic regression analysis showed that a lower maternal education level was a risk factor for resilience level, and a high positive coping style score and gender were protective factors for resilience level.DiscussionThere are group differences in the resilience of medical students, which suggests that school health workers should formulate targeted intervention programs for different types of students to improve their resilience and mental health, and further more, this study reminds mental health workers in colleges and universities to pay more attention to the mental health status of female medical students whose parents are less educated.
Investigating undergraduate students’ engagement in systems thinking and modeling using causal maps
Authors: Sabel Jaime L. , Zangori Laura , Parsley Kathryn M. , Sous Sedra , Koontz Jason 
Published: May 2023

IntroductionTo develop a foundation of scientific understanding, undergraduate biology students need to integrate ideas about individual concepts into thinking about complex biological systems.MethodsTo investigate the extent to which undergraduate students engage in systems thinking, we conducted a pre-post study with students in a required undergraduate botany course at a small liberal arts college in the Midwest. All students in the study completed a causal map at the beginning and end of the course. Casual maps are similar to concept maps but demonstrate cause and effect relationships rather than other connections included in a concept map.ResultsAnalysis showed that the majority of students did see some connections within the system but did not reach a high level of systems thinking.DiscussionThis work highlights the difficulties undergraduate students have with engaging in systems thinking but provides important insight into the particular areas in which students do engage in more complex thinking and areas in which we can specifically target with instruction and intervention.
Association of serum water-soluble vitamin exposures with the risk of metabolic syndrome: results from NHANES 2003-2006
Authors: Pei Xun , Yao Junjie , Ran Simiao , Lu Haifei , Yang Shuo , Zhang Yini , Wang Miyuan , Shi Heyuan , Tan Aihua 
Published: May 2023

IntroductionExisting evidence suggests an association between certain vitamins and metabolic syndrome (MetS), but few epidemiological studies have focused on the effects of multivitamin co-exposure on MetS. This study aims to investigate the associations of the individual or multiple water-soluble vitamins (i.e., vitamin C (VC), vitamin B9 (VB9), and vitamin B12 (VB12)) with co-exposure to MetS, as well as the dose-response relationships among them.MethodsA cross-sectional study was conducted by employing the National Health and Examination Surveys (NHANESs) 2003-2006. Multivariate-adjusted logistic regression models were used to explore the association between individual serum water-soluble vitamins and the risk of MetS and its components, including waist circumference, triglyceride, high-density lipoprotein, blood pressure, and fasting plasma glucose. Restricted cubic splines were performed to explore the dose-response relationships among them. The quantile g-computation method was adopted to explore the associations of multiple water-soluble vitamins co-exposure with MetS risk and MetS components.ResultsA total of 8983 subjects were involved in the study, of whom 1443 were diagnosed with MetS. The MetS groups had a higher proportion of participants with age ≥60 years, BMI ≥30 kg/m2, and insufficient physical activity. Compared with the lowest quartile, the third (OR=0.67, 95% CI: 0.48, 0.94) and highest quartiles (OR=0.52, 95%CI: 0.35, 0.76) of VC were associated with lower MetS risk. Restricted cubic splines showed negative dose-response relationships among VC, VB9 and VB12, and MetS. Regarding MetS components, higher VC quartiles were associated with lower waist circumference, triglyceride, blood pressure, and fasting plasma glucose, while higher VC and VB9 quartiles were associated with higher high-density lipoprotein (HDL). Co-exposure to VC, VB9, and VB12 was significantly inversely associated with MetS, with ORs (95% CI) of 0.81 (0.74, 0.89) and 0.84 (0.78, 0.90) in the conditional and marginal structural models, respectively. Furthermore, we found that VC, VB9, and VB12 co-exposure were negatively associated with waist circumference and blood pressure, while VC, VB9, and VB12 co-exposure were positively associated with HDL.ConclusionThis study revealed negative associations of VC, VB9, and VB12 with MetS, while the high water-soluble vitamin co-exposure was associated with a lower MetS risk.
Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics
Authors: Yang Jing , Zhang Xiaodi , Zhong Mei , Bai Yanhui , Liu Wentao , Hu Jinge , Wang Weiqun 
Published: May 2023

AimsTo investigate the differences between 0.2 and 0.15% brimonidine tartrate eye drops for anti-mydriatic effects and the optical quality under different light conditions.MethodsThis prospective study involved 80 consecutive high myopia patients undergoing implantation of a V4c ICL. The patients were randomly instilled with brimonidine 0.2 and 0.15% 2 weeks postoperatively. Visual quality, pupil center, pupil size, and refraction under different light conditions were measured before and 0.5 h after brimonidine administration. A symptom questionnaire was also evaluated.ResultsThere was no statistical difference in the static and dynamic pupil diameters and velocity after LS between the two groups (p &gt; 0.05). The 0.2% group had significant changes in pupil center before and after treatment, while there was no obvious movement of the 0.15% group under all illumination condition (p &gt; 0.05). The OSI after treatment of the 0.15% group was lower than that of 0.2% group (p = 0.012). The PVA9% and PVA100% of the 0.15% group was higher than that of 0.2% group in the dark (p = 0.009, p = 0.012). The HOA RMS of the 0.15% group was lower than that of 0.2% group (p = 0.016). The QIRC score in the 0.15% group was significantly higher than that in the 0.2% group (p = 0.043).Conclusion0.15 and 0.2% brimonidine tartrate eye drops had similar anti-mydriatic ability, while 0.15% group had better visual quality than 0.2% concentration, and hardly introduced pupil shift. 0.15% brimonidine tartrate eye drops may be more suitable for patients with nocturnal glare symptoms in the early postoperative period after ICL implantation.
Thirty years of research on traumatic brain injury rehabilitation: a bibliometric study
Authors: Liu Yang , Yao Xiaomeng , Qian Jinghua 
Published: May 2023

BackgroundTraumatic brain injury (TBI) is a major public health concern with far-reaching consequences on individuals’ lives. Despite the abundance of works published on TBI rehabilitation, few studies have bibliometrically analyzed the published TBI rehabilitation research. This study aims to characterize current international trends and global productivity by analyzing articles on TBI rehabilitation using bibliometric approaches and visualization methods.MethodsWe conducted a bibliometric analysis of data retrieved and extracted from the Web of Science Core Collection database to examine the evolution and thematic trends in TBI rehabilitation research up until December 31, 2022. The specific characteristics of the research articles on TBI rehabilitation were evaluated, such as publication year, countries/regions, institutions, authors, journals, research fields, references, and keywords.ResultsOur analysis identified 5,541 research articles on TBI rehabilitation and observed a progressive increase in publications and citations over the years. The United States (US, 2,833, 51.13%), Australia (727, 13.12%), and Canada (525, 9.47%) were the most prolific countries/regions. The University of Washington (226, 4.08%) and Hammond FM (114, 2.06%) were the most productive institution and author, respectively. The top three productive journals were Brain Injury (862; 15.56%), Archives of Physical Medicine and Rehabilitation (630; 11.37%), and Journal of Head Trauma Rehabilitation (405, 7.31%). The most frequent research fields were Rehabilitation, Neurosciences, and Clinical Neurology. Co-citation references primarily addressed “outcome assessment,” “community integration” and “TBI management,” and “injury chronicity” and “sequelae” have gained more attention in recent years. “Mild TBI,” “outcome,” “stroke” and “children” were the commonly used keywords. Additionally, the analysis unveiled emerging research frontiers, including “return to work,” “disorder of consciousness,” “veterans,” “mild TBI,” “pediatric,” “executive function” and “acquired brain injury.”ConclusionThis study provides valuable insights into the current state of TBI rehabilitation research, which has experienced a rapid increase in attention and exponential growth in publications and citations in the last three decades. TBI rehabilitation research is characterized by its multi-disciplinary approach, involving fields such as Rehabilitation, Neurosciences, and Clinical Neurology. The analysis revealed emerging research subjects that could inform future research directions.
Speech rehabilitation in children with cochlear implants using a multisensory (French Cued Speech) or a hearing-focused (Auditory Verbal Therapy) approach
Authors: Van Bogaert Lucie , Machart Laura , Gerber Silvain , Lœvenbruck Hélène , Vilain Anne ,   Consortium EULALIES
Published: May 2023

IntroductionEarly exposure to a rich linguistic environment is essential as soon as the diagnosis of deafness is made. Cochlear implantation (CI) allows children to have access to speech perception in their early years. However, it provides only partial acoustic information, which can lead to difficulties in perceiving some phonetic contrasts. This study investigates the contribution of two spoken speech and language rehabilitation approaches to speech perception in children with CI using a lexicality judgment task from the EULALIES battery. Auditory Verbal Therapy (AVT) is an early intervention program that relies on auditory learning to enhance hearing skills in deaf children with CI. French Cued Speech, also called Cued French (CF), is a multisensory communication tool that disambiguates lip reading by adding a manual gesture.MethodsIn this study, 124 children aged from 60 to 140 months were included: 90 children with typical hearing skills (TH), 9 deaf children with CI who had participated in an AVT program (AVT), 6 deaf children with CI with high Cued French reading skills (CF+), and 19 deaf children with CI with low Cued French reading skills (CF-). Speech perception was assessed using sensitivity (d’) using both the hit and false alarm rates, as defined in signal-detection theory.ResultsThe results show that children with cochlear implants from the CF- and CF+ groups have significantly lower performance compared to children with typical hearing (TH) (p &lt; 0.001 and p = 0.033, respectively). Additionally, children in the AVT group also tended to have lower scores compared to TH children (p = 0.07). However, exposition to AVT and CF seems to improve speech perception. The scores of the children in the AVT and CF+ groups are closer to typical scores than those of children in the CF- group, as evidenced by a distance measure.DiscussionOverall, the findings of this study provide evidence for the effectiveness of these two speech and language rehabilitation approaches, and highlight the importance of using a specific approach in addition to a cochlear implant to improve speech perception in children with cochlear implants.
Capturing the power of seizures: an empirical mode decomposition analysis of epileptic activity in the mouse hippocampus
Authors: Molnár László , Ferando Isabella , Liu Benjamin , Mokhtar Parsa , Domokos József , Mody Istvan 
Published: May 2023

IntroductionVarious methods have been used to determine the frequency components of seizures in scalp electroencephalography (EEG) and in intracortical recordings. Most of these methods rely on subjective or trial-and-error criteria for choosing the appropriate bandwidth for filtering the EEG or local field potential (LFP) signals to establish the frequency components that contribute most to the initiation and maintenance of seizure activity. The empirical mode decomposition (EMD) with the Hilbert-Huang transform is an unbiased method to decompose a time and frequency variant signal into its component non-stationary frequencies. The resulting components, i.e., the intrinsic mode functions (IMFs) objectively reflect the various non-stationary frequencies making up the original signal.Materials and methodsWe employed the EMD method to analyze the frequency components and relative power of spontaneous electrographic seizures recorded in the dentate gyri of mice during the epileptogenic period. Epilepsy was induced in mice following status epilepticus induced by suprahippocampal injection of kainic acid. The seizures were recorded as local field potentials (LFP) with electrodes implanted in the dentate gyrus. We analyzed recording segments that included a seizure (mean duration 28 s) and an equivalent time period both before and after the seizure. Each segment was divided into non-overlapping 1 s long epochs which were then analyzed to obtain their IMFs (usually 8–10), the center frequencies of the respective IMF and their spectral root-mean-squared (RMS) power.ResultsOur analysis yielded unbiased identification of the spectral components of seizures, and the relative power of these components during this pathological brain activity. During seizures, the power of the mid frequency components increased while the center frequency of the first IMF (with the highest frequency) dramatically decreased, providing mechanistic insights into how local seizures are generated.DiscussionWe expect this type of analysis to provide further insights into the mechanisms of seizure generation and potentially better seizure detection.