bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetic study of Ru(III) – catalyzed oxidation of L-phenylalanine by hexacyanoferrate(III) in an anionic surfactant medium
Authors: Srivastava Abhishek , Singh Ruchi , Srivastava Neetu , Naik Radhey Mohan 
Published: June 2023

AbstractThe kinetic investigation of Ru(III) promoted oxidation of L-phenylalanine (L-PheAla) by [Fe(CN)6]3−has been performed in anionic sodium dodecyl sulfate (SDS) micellar medium by recording the decrease in absorbance at 420 nm corresponding to [Fe(CN)6]3−using an UV–visible spectrophotometer. Using the pseudo-first-order condition, the course of the reaction was studied as a function of [Fe(CN)63−], ionic strength, [OH−], [SDS], [Ru3+], [L-PheAla] and temperature by changing one variable at a time. The results exhibit that [OH−], [SDS], and [L-PheAla] are the crucial parameters that have an appreciable influence on the reaction rate. The reaction exhibits first-order kinetics in concentration ranges of Ru(III), [Fe(CN)6]3−and at low [L-PheAla] and [OH−] concentrations. The incremental trend observed in the reaction rate with electrolyte concentration shows a positive salt effect. The reaction rate is almost 10 times faster in SDS micellar medium than in aqueous medium. [Fe(CN)6]3−has no appreciable effect on the CMC of SDS, since the polar head of SDS and [Fe(CN)6]3−are both negatively charged. The K+obtained from K3[Fe(CN)6] and KNO3decreases the repulsion between the negatively charged heads of the surfactant molecules, which decreases the CMC of SDS. The activation parameters also support the outer-sphere electron transfer mechanism.
La importancia de la inteligencia artificial en las comunicaciones en los procesos marketing
Authors: Zúñiga Freddy , Mora Poveda Diego Alejandro , Molina Mora Diego Patricio 
Published: June 2023

En estos días ya no es inusual hablar de marketing, y que es lo que conlleva el empleo del mismo dentro de las organizaciones, sabemos que se ocupa de cada interacción posible entre las empresas y las personas, y por qué no decirlo, el marketing permite alcanzar los objetivos organizacionales por medio de la creación de experiencias cada vez más adaptables e inteligentes para los clientes, para ello es necesario el despliegue de tres tipos de capacidades: creativas, analíticas y tecnológicas, en el uso de estas capacidades es donde interviene el empleo de la inteligencia artificial; la correcta aplicación de esta, permite la optimización de recursos y disminución de costes; pero sobre todo tiene un impacto transcendental para los clientes, ya que facilita el anticiparnos a las necesidades de ellos y ofrecer soluciones a las mismas, inclusive antes de que ellos las busquen mediante el análisis predictivo; o, empleando cookies, técnicas Deep learning y el uso de chatbots, se pueda obtener datos de variadas fuentes de información para crear contenido de publicidad lo más personalizada posible. Este artículo pretende realizar una exhaustiva revisión bibliográfica sobre esta temática, teniendo como base información que han sido publicadas en bases de datos científicas, que permitan obtener un marco de referencia sobre la importancia del empleo de la inteligencia artificial en el marketing, que afirme que el uso de IA en el marketing actual es vital para la evolución, adaptabilidad y supervivencia de las organizaciones en este nuevo mundo de transformación digital 4.0.
A sterol‐PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response
Authors: Ovejero Sara , Kumanski Sylvain , Soulet Caroline , Azarli Julie , Pardo Benjamin , Santt Olivier , Constantinou Angelos , Pasero Philippe , Moriel‐Carretero María 
Published: June 2023

AbstractUpon DNA damage, cells activate the DNA damage response (DDR) to coordinate proliferation and DNA repair. Dietary, metabolic, and environmental inputs are emerging as modulators of how DNA surveillance and repair take place. Lipids hold potential to convey these cues, although little is known about how. We observed that lipid droplet (LD) number specifically increased in response to DNA breaks. Using Saccharomyces cerevisiae and cultured human cells, we show that the selective storage of sterols into these LD concomitantly stabilizes phosphatidylinositol‐4‐phosphate (PI(4)P) at the Golgi, where it binds the DDR kinase ATM. In turn, this titration attenuates the initial nuclear ATM‐driven response to DNA breaks, thus allowing processive repair. Furthermore, manipulating this loop impacts the kinetics of DNA damage signaling and repair in a predictable manner. Thus, our findings have major implications for tackling genetic instability pathologies through dietary and pharmacological interventions.
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1‐dependent manner
Authors: Shi Munan , Hou Jiajia , Liang Weichu , Li Qianwen , Shao Shan , Ci Shusheng , Shu Chuanjun , Zhao Xingqi , Zhao Shanmeizi , Huang Miaoling , Wu Congye , Hu Zhigang , He Lingfeng , Guo Zhigang , Pan Feiyan 
Published: June 2023

AbstractHomologous recombination (HR), a form of error‐free DNA double‐strand break (DSB) repair, is important for the maintenance of genomic integrity. Here, we identify a moonlighting protein, glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH), as a regulator of HR repair, which is mediated through HDAC1‐dependent regulation of RAD51 stability. Mechanistically, in response to DSBs, Src signaling is activated and mediates GAPDH nuclear translocation. Then, GAPDH directly binds with HDAC1, releasing it from its suppressor. Subsequently, activated HDAC1 deacetylates RAD51 and prevents it from undergoing proteasomal degradation. GAPDH knockdown decreases RAD51 protein levels and inhibits HR, which is re‐established by overexpression of HDAC1 but not SIRT1. Notably, K40 is an important acetylation site of RAD51, which facilitates stability maintenance. Collectively, our findings provide new insights into the importance of GAPDH in HR repair, in addition to its glycolytic activity, and they show that GAPDH stabilizes RAD51 by interacting with HDAC1 and promoting HDAC1 deacetylation of RAD51.
ANALISIS PEMBUATAN COWL DRAPERY DENGAN TEKNIK DRAPING PADA BUSANA
Authors: Nurlita Ela , Yasnidawati Yasnidawati 
Published: June 2023

Abstract. This study aims to describe the results of cowl drapery using the draping technique. The type of research used is applied research. The object of research is cowl drapery using draping technique. The research instrument uses an assessment format with a Likert Scale. The assessment is carried out by 3 panelists, namely lecturers who are experts in the field of clothing, by fitting. The data analysis technique used is quantitative descriptive and inferential analysis. The results of the cowl drapery using the draping technique show that the results of the cowl drapery using the draping technique obtained an assessment result with a percentage value of 80.21% categorized as appropriate. Based on the t-test, it was found that the average results were significant between the results of cowl drapery using the draping technique with a significance level of 0.05.
Keywords: Cowl drapery; draping;

Abstrak. Penelitian ini bertujuan untuk untuk mendeskripsikan hasil cowl drapery menggunakan Teknik Draping. Jenis penelitian yang digunakan adalah penelitian terapan. Objek penelitian yaitu cowl drapery menggunakan teknik draping. Instrumen penelitian memakai format penilaian dengan Skala Likert. Penilaian dilakukan oleh 3 orang panelis yaitu dosen yang ahli dalam bidang busana, dengan cara fitting. Teknik analisis data yang digunakan adalah deskriptif kuatitatif dan analisis inferensial. Hasil cowl drapery menggunakan Teknik Draping menunjukkan hasil cowl drapery menggunakan teknik draping didapatkan hasil penilaian dengan nilai persentase sebesar 80.21 % dikategorikan Sesuai. Berdasarkan uji t didapatkan hasil rata-rata penilaian yang signifikan antara hasil jadi cowl drapery menggunakan teknik draping dengan taraf signifikansi sebesar 0.05.
Kata Kunci: Cowl drapery; draping;
TUNIK MENGGUNAKAN PENGAPLIKASIAN TEKNIK COLET-BOSHI SHIBORI PADA WANITA KARIR DENGAN BENTUK TUBUH PENDEK GEMUK
Authors: ERMALENA SITI SARAH , WENING SRI , BUDIASTUTI EMY 
Published: June 2023

Abstrak. Tujuan penelitian ini adalah untuk mengetahui cara pembuatan motif menggunakan teknik colet-boshi shibori, mengembangkan desain tunik mengetahui hasil uji produk tunik untuk wanita karir dengan bentuk tubuh tidak ideal. Penelitian ini merupakan jenis penelitian pengembangan (R&D) menggunakan model PPE (Planning, Production and Evaluation). Metode pengumpulan datanya sendiri menggunakan studi literature, angket (kuisioner) dan dokumentasi. Sedangkan teknik analisis data yang digunakan menggunakan 3 teknik yaitu : (1) pengukuran persepsi visual, (2) uji validasi isi, dan (3) analisis data deskriptif kuantitatif untuk uji kelayakan produk. Hasil uji produk tunik yang diperoleh dari hasil rerata penilaian ahli (judgement expert) yang terdiri dari 3 orang ahli yaitu : 94,3, 88,6 dan 91,4. Rerata dari ketiga penilaian adalah 91,4. Berdasarkan hasil rerata tersebut maka pengembangan teknik colet dan bosgi shibori pada wanita karir dengan bentuk tubuh tidak ideal memiliki kualifikasi sangat baik dengan pencapaian 91,4%.
Kata Kunci: tunik, teknik colet, teknik boshi, shibori, wanita, karir, bentuk tubuh pendek gemuk
Patterns of knowledge and use of tropical plants in homegardens of Southern Morelos, Mexico
Authors: Ortiz-Sánchez Amanda , Romero-Manzanares Angélica , Monroy-Ortiz Columba , Luna Cavazos Mario 
Published: June 2023

The aim of this research is to identify the patterns of use and knowledge of plant species growing in selected tropical homegardens in southern Morelos, Mexico. The method consisted of obtaining informed consent, interviews with homegarden managers, recording socioeconomic data, visits to the interior of each selected homegarden, and personal observations. Data were analyzed through multivariate analyses. The results included a floristic composition (132 species) and eight types of use. Grouping of homegardens by type of use differentiated two main groups: homegardens where principal use is for food plants, and others mainly for ornamental plants. Were found significant differences between homegardens by the number of species and type of use. The grouping of species by number of uses revealed two groups; the patterns of use of plants in homegardens differed according to the user’s preferences; multiuse species were appreciated in group two, which dominated the ornamentals. It was found a significant correlation between age and number of plants known for the owners of the homegardens; while occupation, schooling, and income had no correlation. In conclusion, we rejected the hypothesis of nullity due to differences between richness and the preference of species, the management of homegardens, and by the null influence of the socioeconomic factors studied, with the exception of the age owners and their knowledge of the species.
Future temperature-related excess mortality under climate change and population aging scenarios in Canada
Authors: Hebbern Christopher , Gosselin Pierre , Chen Kai , Chen Hong , Cakmak Sabit , MacDonald Melissa , Chagnon Jonathan , Dion Patrice , Martel Laurent , Lavigne Eric 
Published: June 2023

Abstract
Objective
Climate change is expected to increase global temperatures. How temperature-related mortality risk will change is not completely understood, and how future demographic changes will affect temperature-related mortality needs to be clarified. We evaluate temperature-related mortality across Canada until 2099, accounting for age groups and scenarios of population growth.

Methods
We used daily counts of non-accidental mortality for 2000 to 2015 for all 111 health regions across Canada, incorporating in the study both urban and rural areas. A two-part time series analysis was used to estimate associations between mean daily temperatures and mortality. First, current and future daily mean temperature time series simulations were developed from Coupled Model Inter-Comparison Project 6 (CMIP6) climate model ensembles from past and projected climate change scenarios under Shared Socioeconomic Pathways (SSPs). Next, excess mortality due to heat and cold and the net difference were projected to 2099, also accounting for different regional and population aging scenarios.

Results
For 2000 to 2015, we identified 3,343,311 non-accidental deaths. On average, a net increase of 17.31% (95% eCI: 13.99, 20.62) in temperature-related excess mortality under a higher greenhouse gas emission scenario is expected for Canada in 2090–2099, which represents a greater burden than a scenario that assumed strong levels of greenhouse gas mitigation policies (net increase of 3.29%; 95% eCI: 1.41, 5.17). The highest net increase was observed among people aged 65 and over, and the largest increases in both net and heat- and cold-related mortality were observed in population scenarios that incorporated the highest rates of aging.

Conclusion
Canada may expect net increases in temperature-related mortality under a higher emissions climate change scenario, compared to one assuming sustainable development. Urgent action is needed to mitigate future climate change impacts.
What Do We Need? Accommodations in the Workplace: People with Lupus Share Their Work Experiences
Authors: Calderon Orly , Giffords Elissa D. , Kane Kaycee 
Published: June 2023

This article discusses disability inclusion in the workplace. It identifies barriers and makes recommendations to help meet employment needs of people with disabilities, utilizing lupus as an example. A convergent mixed method design study examined the workplace experiences and needs of individuals with lupus. Availability sampling yielded 1,776 participants from across the United States. The results revealed 69% of the respondents reported lupus symptoms had a negative impact on their employment and 48% of the participants reported needing help or accommodations in the workplace. An inductive thematic content analysis with an inter-coder agreement ranging from 71% to 73%, yielded 4 themes encompassing issues related to productivity, interpersonal relationship in the workplace, and adjustments in work responsibilities and work environment, respectively. The results suggest that training programs about the American with Disability Act may have a positive impact on organizational functioning. Employers have a responsibility to maintain a flexible work environment whenever possible to address variability in employees’ needs. Employers and employees should engage in ongoing discussions that seek to identify the accommodations that will help employees with disabilities meet their workplace responsibilities and to enhance their contribution to the organization. Managers and administrators are encouraged to create an environment that values a diverse workforce, including persons with disabilities.
Tingkat Keberhasilan ASI Ekslusif berdasarkan Tingkat Pendidikan Ibu di Puskesmas Payungrejo Kabupaten Lampung Tengah
Authors: Suja Monica Dara Delia , Puspitarini Zenni , Ayu Riska Nur Suci 
Published: June 2023

Peningkatan cakupan pemberian ASI eksklusif di berbagai negara sedang digalakkan bahkan dengan adanya World Breastfeeding Week diharapkan dapat menggerakkan masyarakat untuk lebih memilih ASI eksklusif dibandingkan dengan susu formula. Cakupan ASI eksklusif di Lampung Tengah yang ditunjuk sebagai lokus stunting perlu ditingkatkan. Saat ini belum ada penelitian tentang keberhasilan ASI Eksklusif berdasarkan tingkat pendidikan ibu. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat pendidikan ibu dan ASI eksklusif di Puskesmas Payungrejo Kabupaten Lampung Tengah. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross-sectional. Populasi penelitian yaitu seluruh ibu yang memiliki bayi usia 6-59 bulan. Sampel penelitian ini adalah ibu yang memiliki bayi berusia 6-59 bulan dan total sampel sebesar 47 orang responden yang dipilih dengan metode simple random sampling. Variabel bebas dalam penelitian ini adalah tingkat pendidikan ibu dan variabel tergantung adalah ASI eksklusif. Instrumen yang digunakan dalam penelitian ini adalah berupa kuesioner yang diajukan kepada Ibu dari balita tersebut. Analisis data bivariat menggunakan uji statistik chi-square. bahwa ibu yang memberikan ASI eksklusif yaitu sebanyak 27 orang (57,45%). Tingkat pendidikan ibu paling banyak adalah tingkat pendidikan rendah sebanyak 32 orang (68,09%). Ada hubungan antara tingkat pendidikan ibu dan keberhasilan pemberian ASI eksklusif (p<0,005). Ibu yang menempuh pendidikan tinggi memiliki kemungkinan 2 kali lebih tinggi untuk memberikan ASI eksklusif (OR= 2,05). Pemberian edukasi pentingnya ASI eksklusif dan informasi tentang manajemen laktasi kepada ibu yang pendidikan rendah tentang pentingnya pemberian ASI eksklusif harus lebih diprioritaskan.
Quality of cow dung composting fertilizer with additional starter solution of cow rumen contents
Authors: Nurdiansyah Amirul , Pribadi Arqowi , Suprayogi Dedy , Karami Abdillah Akmal 
Published: June 2023

RPH Kedurus produces livestock solid waste in the form of cow dung as much as 750 kg/day and the content of cow rumen is 2 tons/day. The livestock solid waste can be processed by turning it into compost using the takakura composting method. This study aims to determine the characteristics of the compost according to the specified parameters (temperature, pH, moisture content, organic c, nitrogen, phosphorus, potassium, and the C/N ratio) and to determine the dose of use of a good cow rumen content solution to produce compost according to the quality standard of SNI 19-7030-2004. In this study, the treatments used were P0 with a composition of 3 kg of cow dung and 1 kg of rice husks, P1 with a composition of P0 and 100 mL of starter solution of cow rumen contents, P2 with a composition of P0 and 200 mL of starter solution of cow rumen contents, and P3 with a composition of P0 and 300 mL of starter solution for bovine rumen contents. Overall, the characteristics produced by the four treatments met the quality standards, while the optimum dosage for the use of rumen contents was found in treatment P2 with the use of 200 mL of starter bovine rumen contents and produced a temperature of 29 °C, pH 7.4, water content 14.2%, C. -organic 67 %, nitrogen 4.26 %, phosphorus P2O5 0.37 %, potassium K2O 2.21 %, and C/N ratio 15.7. The compost fertilizer produced can be used as an alternative organic fertilizer to be developed.
Performance of diesel engine with biodiesel fuel from cooking oil
Authors: Marlinda Marlinda , Suparno Suparno , Ramli Ramli , Irwan M. , Yandi M. K. 
Published: June 2023

Biodiesel from used cooking oil is a very potential material to replace diesel fuel. Besides being cheap, it can also reduce waste. The purpose of the study was to determine the performance of the Nissan SD22 diesel engine on the use of biodiesel as fuel and the optimum composition of biodiesel and diesel mixtures. The results of the diesel engine performance show that a high rotational speed of 2800 rpm could produce a torque of 112 N.m at B10, while the results for the power parameter at a rotational speed of 2750 rpm produced a large power of 33.46 KW for B10. As for fuel consumption for a rotation speed of 2750 rpm, B10 fuel provided 0.293 kg/(kW.hour) of specific fuel while Pertamina Dex requires 0.310 kg/(kW.hour) of specific fuel, meaning that the use of B10 saved 5.48% more than B10. As for fuel consumption for a rotation speed of 2750 rpm, B10 fuel provides 0.293 kg/kW.hour of specific fuel while Pertamina Dex requires 0.310 kg/kW.hour of specific fuel, meaning that the use of B10 saves 5.48% more than B10. Biodiesel B10 is able to provide good performance for use as a diesel engine fuel. The resulting gas emissions are smaller than diesel emissions. This proves that biodiesel is an environmentally friendly fuel.
Utilization of water lily activated charcoal as a biofilter in tofu wastewater treatment
Authors: Khamidah Noor , Nugraha Muhammad Imam , Sari Novita Kurnia 
Published: June 2023

The purpose of this study was to determine the effect of water lily activated charcoal as a biofilter in tofu wastewater treatment and to determine the effective dose of water lily activated charcoal as a biofilter in tofu wastewater treatment. The results showed that water lily activated charcoal can be used to improve the quality of tofu liquid waste; thus, it can improve the quality of tofu liquid waste which can be seen from the parameters of TSS (Total Suspended Solid). The treatment dose of 2 g of activated charcoal (A3) is the best dose to improve the quality of tofu liquid waste and has complied with the 2014 LH regulation concerning the quality standards of wastewater for the tofu industry, namely the parameters of TSS. The existence of this research can be a reference for further similar research by utilizing organic matter as an alternative in tofu wastewater treatment.
Production of biogas from coffee husk waste with rumen fluid and mixture of rumen fluid and cow dung
Authors: Anwar Hasrul , Ulya Ridho , Djana Miftahul , Mayasari Rizka 
Published: June 2023

Coffee is the second largest traded commodity in the world and also produces by-products and residues. Coffee husk waste is an abundant lignocellulosic material and has the potential to be used as raw material for biogas production. This study compared the production of biogas from coffee husk using rumen fluid with a mixture of rumen fluid and cow dung. In the pretreatment process using ethanol, the waste consisted of 65.90% cellulose, 24.95% hemicellulose, 0.21% lignin, 2.16% pectin, 1.08% protein, 3.11% tannins, 0.91% caffeine, and 3.78% polyphenols. The decrease in TS (total solid) and VS (volatile solid) values for C-RC (coffee-rumen fluid-cow dung) was greater than for C-R (coffee-rumen fluid) as 32.20% and 42.47% were obtained for C-RC, while the values for C-R were 19.32% and 38.37 The VFA (volatile fatty acids) values for C-R and C-RC were 1.09% and 2.24%. The biogas produced for C-R was CH4 of 14.4%, CO2 of 13.75%, and H2 of 0.59%, while that for C-RC consisted of CH4 of 22.3%, CO2 of 4.11%, and H2 of 0.36%. The yield of biogas for C-R was 0.48 Nm3/(kg COD removal) and for C-RC was 1.95 Nm3 /(kg COD removal).