bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo ureteroscopic intrarenal pressures and clinical outcomes: a multi‐institutional analysis of 120 consecutive patients
Authors: Croghan Stefanie M. , Cunnane Eoghan M. , O'Meara Sorcha , Muheilan Muheilan , Cunnane Connor V. , Patterson Kenneth , Skolarikos Andreas , Somani Bhaskar , Jack Gregory S. , Forde James C. , O'Brien Fergal J. , Walsh Michael T. , Manecksha Rustom P. , McGuire Barry B. , Davis Niall F. 
Published: September 2023

ObjectivesTo evaluate the pressure range generated in the human renal collecting system during ureteroscopy (URS), in a large patient sample, and to investigate a relationship between intrarenal pressure (IRP) and outcome.Patients and MethodsA prospective multi‐institutional study was conducted, with ethics board approval; February 2022–March 2023. Recruitment was of 120 consecutive consenting adult patients undergoing semi‐rigid URS and/or flexible ureterorenoscopy (FURS) for urolithiasis or diagnostic purposes. Retrograde, fluoroscopy‐guided insertion of a 0.036‐cm (0.014″) pressure guidewire (COMET™ II, Boston Scientific, Marlborough, MA, USA) to the renal pelvis was performed. Baseline and continuous ureteroscopic IRP was recorded, alongside relevant operative variables. A 30‐day follow‐up was completed. Descriptive statistics were applied to IRP traces, with mean (sd) and maximum values and variance reported. Relationships between IRP and technical variables, and IRP and clinical outcome were interrogated using the chi‐square test and independent samples t‐test.ResultsA total of 430 pressure traces were analysed from 120 patient episodes. The mean (sd) baseline IRP was 16.45 (5.99) mmHg and the intraoperative IRP varied by technique. The mean (sd) IRP during semi‐rigid URS with gravity irrigation was 34.93 (11.66) mmHg. FURS resulted in variable IRP values: from a mean (sd) of 26.78 (5.84) mmHg (gravity irrigation; 12/14‐F ureteric access sheath [UAS]) to 87.27 (66.85) mmHg (200 mmHg pressurised‐bag irrigation; 11/13‐F UAS). The highest single pressure peak was 334.2 mmHg, during retrograde pyelography. Six patients (5%) developed postoperative urosepsis; these patients had significantly higher IRPs during FURS (mean [sd] 81.7 [49.52] mmHg) than controls (38.53 [22.6] mmHg; P < 0.001).ConclusionsA dynamic IRP profile is observed during human in vivo URS, with IRP frequently exceeding expected thresholds. A relationship appears to exist between elevated IRP and postoperative urosepsis.
Champions of democracy or agents of professionalization? The extension era at the universities of Toronto, Queen's, and McMaster
Authors: McLean Scott 
Published: September 2023

AbstractI narrate a historical sociology of extension work undertaken at Queen's University, McMaster University, and the University of Toronto from the late 1800s through the early 1960s. University administrators positioned extension work as dedicated to the democratization of higher education. However, a critical analysis of archival data reveals that the rise and fall of extension reflected these universities’ material interests and organizational goals relating to public relations, government relations, and enrollment growth. Further, extension programs at these universities were primarily oriented to providing alternative credential pathways to those seeking professional status as schoolteachers, accountants, bankers, and business managers. Indeed, extension leaders demonstrated substantial agency in the professionalization of these fields. Contributing to the historical sociology of higher education and the professions, I argue that the extension era in Ontario resulted in partial democratization of higher education whilst helping to construct mechanisms of social closure rooted in credentialism and professionalization.
Research on a colour solid built by gridded colour mixing of nine primary‐coloured fibres and its neural network colour prediction approach
Authors: Sun Xianqiang , Xue Yuan , Xue Jingli , Jin Guang 
Published: September 2023

AbstractAccording to the demand for colour prediction for coloured yarn, two adjacent colours chosen from red (R), yellow (Y), green (G), cyan (C), blue (B) and magenta (M) fibres were combined with fibres of dark grey (O1), medium grey (O2) and light grey (O3), respectively, and then ternary coupling‐superposition mixing was performed to acquire a colour solid consisting of three lightnesses, 18 colour mixing units and 18 × (m + 1) × n grid points. An integrated colour mixing with 20% hue gradient and 33.33% saturation gradient was performed to achieve a colour solid containing 360 grid points, then using it as the sample space for the colour prediction model. A total of 360 typical samples were established by the grid points, 213 yarns and fabrics were prepared by the typical sample parameters, and the corresponding reflectance was accessed by a spectrophotometer. Neural network models for predicting reflectance by mixing ratios as well as forecasting mixing ratios by reflectance, were established. The 12 non‐grid point parameters were chosen to prepare corresponding yarns and fabrics, and the corresponding reflectance was measured. The predicted and measured values of the neural network model were compared to verify its predictive ability and generalisability. The results showed that when predicting the colour by the mixing ratios, the colour difference between the predicted and measured samples ranged from 1.5 to 3.4, with an average of 2.4; and when forecasting the mixing ratios by the colour, the colour difference ranged from 0.8 to 5.6, with an average of 2.4.
The emperor has no clothes: A systemic view of the status and future of child custody evaluation (CCE)
Authors: Garber Benjamin D. 
Published: September 2023

AbstractFor all of the time, effort, and money invested in child custody evaluation (CCE) and for all of evaluators' emphases on collecting empirically sound data, CCE is not itself an empirically robust process. The reliability, validity, efficacy, and efficiency of CCE has never yet been adequately demonstrated. The science has yet even to define and measure the variables that constitute a healthy family, much less how one is to measure and recommend changes for conflicted systems in the midst of tectonic transitions. This article proposes five ways in which family law professionals and the culture at large should work to better serve the needs of our children: (1) the establishment of proactive parenting and co‐parenting education intended to diminish the frequency and magnitude of family conflict and improve the quality of child and family functioning; (2) the introduction of organized incentives that motivate healthy parenting and co‐parenting practices as opposed to negative consequences that do too‐little, too‐late; (3) a greater emphasis on social equity, cultural humility, and universal professional training; (4) the creation of ethical guidelines that disconnect continuing conflict from professional income; and (5) outcome research that feeds back into the evolution of these and related processes.
RETRACTED: Relationship between body mass index and mortality of burns patients: A systematic review and meta‐analysis
Authors: Al‐dolaimy F. , Abdul‐Reda Hussein Uday , Hadi Kzar Mazin , Saud Abdulnaser , Abed Jawad Mohammed , Yaseen Hasan Saif , Alhassan Muataz S. , Hussien Alawadi Ahmed , Alsaalamy Ali , Farzan Ramyar 
Published: September 2023

AbstractThis systematic review and meta‐analysis aimed to evaluate the relationship between body mass index (BMI) and mortality of burn patients. A comprehensive, systematic search was conducted in different international electronic databases, such as Scopus, PubMed, Web of Science and Persian electronic databases such as Iranmedex, and Scientific Information Database (SID) using keywords extracted from Medical Subject Headings such as “Body mass index”, “Burns” and “Mortality” from the earliest to the April 1, 2023. The quality of the studies included in this systematic review was evaluated using the appraisal tool for cross‐sectional studies (AXIS tool). Finally, six articles were included in this systematic review and meta‐analysis. A total of 16 154 burn patients participated in six studies. Their mean age was 46.32 (SD = 1.99). Of the participants, 71.7% were males. The mean length of hospitalization was 18.80 (SD = 8.08) days, and the average TBSA in burn patients was 38.32 (SD = 2.79) %. Also, the average BMI in burn patients was 27.10 (SD = 1.75). Results found mortality in patients with abnormal BMI (overweight to morbidity BMI) was 0.19 more than normal BMI (ES: 1.19, 95%CI: 0.76–1.87, Z = 0.75, I2: 71.8%, p = 0.45). Results of linear dose–response showed each 5 kg/m2 increase in BMI was associated with a 5% increase in mortality that was marginally significant (ES: 1.05, 95%CI: 1.00–1.11, Z = 1.99, I2: 22.2%, p = 0.047). There was a non‐linear relationship between levels of BMI and mortality (Prob > χ2 = 0.02). There was an increase in mortality from percentile 10 to 50, although it was not significant (Correlational coefficient: 0.01, p = 0.85). Also, there was an increase in mortality rate from percentile 50 to 90 that was statistically significant (correlational coefficient: 0.06, p = 0.047). Finally, the results of the study indicated BMI can increase the chance of mortality by 0.19, although it was not significant. As a result, more studies are needed to better judge the relationship between BMI and mortality in burn victims.
Basin‐scale variables drive macroinvertebrate biomass in low‐order streams across different mountain ecoregions
Authors: Burgazzi Gemma , Laini Alex , Viaroli Pierluigi , Fenoglio Stefano , Schreiner Verena C. , Schäfer Ralf B. , Doretto Alberto 
Published: September 2023

AbstractAimBiomass is an important descriptor of macroinvertebrate communities, providing insights into stream productivity and ecosystem functioning. Nevertheless, the drivers of biomass are still poorly assessed, especially in multiscale studies. Here, we aimed at filling this gap by assessing the relationship between environmental variables measured at patch, reach and basin scale and macroinvertebrate biomass, as well as the transferability of such relationships across different mountain regions.LocationMaritime‐Cottian Alps and the Tuscan‐Emilian Apennine (Northern Italy).TaxaFreshwater macroinvertebrates.MethodsPatch‐, reach‐ and basin‐scale variables, either measured in the field or computed with kriging techniques, were summarised with sparse principal component axes and later used in mixed modelling and variance partitioning to assess the relative effect of environmental variables on macroinvertebrate biomass. An independent model was run for each region, and results were compared to assess the transferability of drivers.ResultsBasin‐scale variables explained most of the biomass variability in both regions, supporting the transferability of results. More specifically, mean cumulated daily precipitation was the main driver of macroinvertebrate biomass. Patch‐ and reach‐scale variables also significantly affected macroinvertebrate biomass, but their relative role varied depending on the region considered, without any clear pattern.Main ConclusionsOverall, we highlighted a dominance of basin‐scale drivers—and specifically of the mean cumulated precipitation—and a consistency of results across different mountain regions. This implies that climatic variables regulate energy fluxes to higher trophic levels and subsidies to both downstream river sections and terrestrial ecosystems. These findings offer insights into ecosystem‐level vulnerability to climate change.
Effects of early exercise on cardiac function and lipid metabolism pathway in heart failure
Authors: de Souza Sérgio Luiz Borges , Mota Gustavo Augusto Ferreira , da Silva Vitor Loureiro , Vileigas Danielle Fernandes , Sant'Ana Paula Grippa , Gregolin Cristina Schmitt , Figueira Rebeca Lopes , Batah Sabrina Setembre , Fabro Alexandre Todorovic , Murata Gilson Masahiro , Bazan Silmeia Garcia Zanati , Okoshi Marina Politi , Cicogna Antonio Carlos 
Published: September 2023

AbstractWe employed an early training exercise program, immediately after recovery from surgery, and before severe cardiac hypertrophy, to study the underlying mechanism involved with the amelioration of cardiac dysfunction in aortic stenosis (AS) rats. As ET induces angiogenesis and oxygen support, we aimed to verify the effect of exercise on myocardial lipid metabolism disturbance. Wistar rats were divided into Sham, trained Sham (ShamT), AS and trained AS (AST). The exercise consisted of 5‐week sessions of treadmill running for 16 weeks. Statistical analysis was conducted by anova or Kruskal–Wallis test and Goodman test. A global correlation between variables was also performed using a two‐tailed Pearson's correlation test. AST rats displayed a higher functional capacity and a lower cardiac remodelling and dysfunction when compared to AS, as well as the myocardial capillary rarefaction was prevented. Regarding metabolic properties, immunoblotting and enzymatic assay raised beneficial effects of exercise on fatty acid transport and oxidation pathways. The correlation assessment indicated a positive correlation between variables of angiogenesis and FA utilisation, as well as between metabolism and echocardiographic parameters. In conclusion, early exercise improves exercise tolerance and attenuates cardiac structural and functional remodelling. In parallel, exercise attenuated myocardial capillary and lipid metabolism derangement in rats with aortic stenosis‐induced heart failure.
Different momentum effects across countries: An explanation based on investors' behavior
Authors: Xia Guoxiao , Hu Changsheng , Xia Huosong , Chi Yangchun 
Published: September 2023

AbstractWe establish a model in which speculators use feedback trading characteristics to infer the behavior of irrational investors and induce them to trade. We also discuss the stability and time series of asset prices. Our results show that: (1) speculators have speculation and arbitrage demands and make “noise” to induce irrational investors to trade, (2) the time series of asset prices show stable momentum and a reversal effect when fundamental traders dominate the market, and (3) momentums are unstable and perform poorly under extreme circumstances. Our article offers a unique approach to understanding the micro mechanism of different momentum effects in various markets and suggests a plausible theoretical framework to illustrate such differences.
Voltage‐gated sodium channels in genetic epilepsy: up and down of excitability
Authors: Rusina Evgeniia , Simonti Martina , Duprat Fabrice , Cestèle Sandrine , Mantegazza Massimo 
Published: September 2023

AbstractThe past two decades have witnessed a wide range of studies investigating genetic variants of voltage‐gated sodium (NaV) channels, which are involved in a broad spectrum of diseases, including several types of epilepsy. We have reviewed here phenotypes and pathological mechanisms of genetic epilepsies caused by variants in NaV α and β subunits, as well as of some relevant interacting proteins (FGF12/FHF1, PRRT2, and Ankyrin‐G). Notably, variants of all these genes can induce either gain‐ or loss‐of‐function of NaV leading to either neuronal hyperexcitability or hypoexcitability. We present the results of functional studies obtained with different experimental models, highlighting that they should be interpreted considering the features of the experimental system used. These systems are models, but they have allowed us to better understand pathophysiological issues, ameliorate diagnostics, orientate genetic counseling, and select/develop therapies within a precision medicine framework. These studies have also allowed us to gain insights into the physiological roles of different NaV channels and of the cells that express them. Overall, our review shows the progress that has been made, but also the need for further studies on aspects that have not yet been clarified. Finally, we conclude by highlighting some significant themes of general interest that can be gleaned from the results of the work of the last two decades.image
Comparison and improvement of RNA extraction methods in Sargassum (Phaeophyta)
Authors: He Weiling , Ke Xiao , Li Tangcheng , Wu Yuming , Tang Xianming , Chen Weizhou , Liu Tao , Du Hong 
Published: September 2023

AbstractSargassum (Sargassaceae) is widely distributed globally and plays an important role in regulating climate change, but the landscape of genomes and transcripts is less known. High‐quality nucleic acids are the basis for molecular biology experiments such as high‐throughput sequencing. Although extensive studies have documented methods of RNA extraction, these methods are not very applicable to Sargassum, which contains high levels of polysaccharides and polyphenols. To find a suitable method to improve the quality of RNA extracted, we compared and modified several popular RNA extraction methods and screened one practical method with three specific Sargassum spp. The results showed that three CTAB methods (denoted as Methods 1, 2, and 3) and the RNAprep Pure Plant Kit (denoted as Method 4) could, with slight modifications, effectively isolate RNA from Sargassum species, except for Method 4 used with S. fusiforme. By performing further screening, we determined Method 4 was the best choice for S. hemiphyllum and S. henslowianum, as revealed by RNA yields, RNA Integrity Number (RIN), extraction time, and unigene mapped ratio. For S. fusiforme, Methods 1, 2, and 3 showed no obvious differences among the yields, quality, or time to perform. In addition, one other method was tested, but we found the quality of the RNA extracted by TRIzol reagent methods (denoted as Method 5) performed the worst when compared with the above four methods. Therefore, our study provides four suitable methods for RNA extraction in Sargassum and is essential for future genetic exploration of Sargassum.
Personality and insomnia: A systematic review and narrative synthesis
Authors: Akram Umair , Stevenson Jodie C. , Gardani Maria , Allen Sarah , Johann Anna F. 
Published: September 2023

SummaryThe inherent nature of personality serves as a predisposing, and possible maintaining, factor of insomnia. However, methodological differences limit the ability to draw causal conclusions regarding the specific traits involved in the aetiology of the disorder. This systematic review of the relationship between insomnia and personality provides a narrative synthesis of the literature to date. Here, we identified N = 76 studies meeting the inclusion/exclusion criteria. The outcomes reliably evidenced the experience of insomnia to be associated with personality traits that are typically considered to be negative or maladaptive in nature. More specifically, insomnia was related to neuroticism, introversion, perfectionistic doubts and concerns, elevated personal standards, negative affect, social inhibition and avoidance, hysteria, hypochondriasis, psychasthenia, impulsive behaviour, anger, hostility, and psychopathic tendencies, schizotypal and borderline traits, reduced conscientiousness and self‐directedness, and negatively perceived perception of the self. Several studies examined the role that personality plays in predicting the treatment efficacy and adherence of CBTi. Moving forward, longitudinal research, methodological consistency, the mediating role of treatment outcomes and adherence, and clinical and population representative samples should be prioritised. Methodological strengths and limitations of the literature are discussed alongside the next steps that should be taken to advance our understanding of the literature.
Broncho‐Vaxom bacterial lysate prevents asthma via acetate enhancement in mouse model
Authors: Lee Seung‐Hwa , Kim Ha‐Jung , Lee So‐Yeon , Hong Soo‐Jong 
Published: September 2023

AbstractPurposeBroncho‐Vaxom (BV) is known to attenuate allergic airway inflammation and chronic bronchitis in humans, but the underlying mechanism of this gut‐mediated immunity remains unclear. This study investigated the effects of an oral BV on gut and systemic short‐chain fatty acids (SCFAs) and immune responses.MethodsOral BV was administered daily for 15 days prior to commencing the study in an asthma mouse model. Asthma was induced by ovalbumin (OVA) sensitization followed by a challenge with 1% OVA by inhalation. Asthmatic phenotypes, gut‐ and systemic‐ immune responses, and SCFAs in the cecum and blood were then investigated.ResultsAirway hyperresponsiveness, total immunoglobulin E production, and pulmonary inflammation were all significantly suppressed by BV. The interleukin‐13 level was also suppressed, whereas TGF‐β expression was increased, in the lungs of the BV‐treated mice. The regulatory T (Treg) cell numbers were increased in the small intestine, and the acetate level was increased in the cecum and serum after BV treatment. The levels of acetate in the cecum and serum were negatively correlated with airway hyperresponsiveness and with the eosinophil numbers in the BAL fluid of the OVA‐induced mice. There was a positive correlation between the acetate levels in the feces and serum and the lung expression of TGF‐β in the asthma mice.ConclusionsOral BV administration appears to prevent allergic inflammation by enhancing Treg cell proliferation and acetate production in an asthmatic mouse model.
Exceptional and banal constructions of British muslims in Grenfell: Social boundaries, twitter, superdiversity and online vernacular memory
Authors: Downing Joseph 
Published: September 2023

AbstractThe Grenfell fire catapulted North Kensington into the spotlight, an area both synonymous with immigration and social policy innovation for over a century. However, it remains under examined how this extraordinary event re‐defined the discursive landscape around British Muslims and how they have been situated in the national landscape. To do this it analyses the twitter activity in the 96 hours after the fire and also the victim profiles published in the Guardian Newspaper. It finds that the narratives that emerge blur British Muslim social boundaries through narratives both around the exceptional and banal narratives which emerged during and after the fire. This constructs British Muslims as both saviours during Grenfell, and also as a super‐diverse population that resists topologizing as pre‐dominantly South Asain. This article also raises broader questions about the not only the role that social media has in the creation of vernacular memory, and also that in this case twitter was importantly not a conduit for the fake news and hate speech created against British Muslims during Grenfell.
International trade and Ukraine's pursuit of self‐determination
Authors: Boyko Natalia , Nes Kjersti , Schaefer K. Aleks 
Published: September 2023

AbstractIn this research, we assess the international trade implications of Ukraine's pursuit of self‐determination through the lens of the EU–Ukraine Association Agreement and the contemporaneous war with Russia in the years preceding the 2022 Russian Invasion. To do so, we construct a dataset with annual, bilateral export and import flows for Ukraine and a set of comparator countries at the 6‐digit level of the Harmonised Tariff Schedule (HS) for years 2000–2019. Using this data, we nest a difference‐in‐difference design within a series of econometric gravity models to estimate the effects on the sectoral and geographic composition of Ukrainian trade. Our results indicate a major re‐direction of exports towards the EU and away from Russia. Trade outcomes are one of many considerations that led to Ukraine's pursuit of EU integration.