bluuebunny/crossref_metadata_2025_split huggingface dataset:
V-040 PRIMARY ABANDON-OF-THE-SAC: A CASE REPORT
Authors: Vera Vasquez C A , Ye Zhou J , Lupu I , Gonzalo Prats B , Homs Samso R , Solans Solerdelcoll M , Gonzalez Lopez J A , Moral Duarte A 
Published: May 2023

Abstract

Background
Inguinal hernia repair is one of the most frequent surgical procedures worldwide. Several minimally invasive approaches have been developed. Laparoscopic hernioplasty offers less pain, faster recovery and a lower incidence of wound infection. However, the best approach in repairing large inguinoscrotal hernias and the optimal management of the distal sac and its risks are still debated. There may be a higher risk of visceral or cord structures damage, ischemic orchitis, seroma or haematoma when opting for a complete dissection of the hernia sac which may extend deep into the scrotum.

Objective
To show a video of a transabdominal preperitoneal (TAPP) approach using the primary abandon of the sac technique. The aim of this is to reduce the complications above-stated.

Method
We report a case of a 33 year old man, without previous abdominal surgery, diagnosed with a large right inguinoscrotal hernia, which appeared 1 year ago and became painful. The patient was scheduled electively for a TAPP surgery.

Results
Surgery was performed by means of day surgery. No intraoperative complications. No seroma nor haematoma detected in the postoperative period.

Conclusion
Laparoscopic best approach of repairing inguinoscrotal hernias are still debatable. The primary abandon of the sac is a feasible and reproducible technique and is a safe manner to overcome the difficulties of the distal sac management.
V-041 ROBOTIC MONOLATERAL TAR FOR LATERAL INCISIONAL HERNIA IN PREVIOUS COLOSTOMY SITE
Authors: Capoccia Giovannini S , Camerini G , Rossi L , Rubartelli A , Carlini F , Longo G , Drago B , Epis L , Stabilini C 
Published: May 2023

Abstract

Background
Novitsky described the Transversus Abdominis Muscle release (TAR) extending the retromuscolar plane (RMP) improving the midline restoration (MR) with high morbidity.
The robotic approach seems to have the same effectiveness reducing wound complications.

Video's comment
A 58-year-old male submitted to Hartmann procedure for acute diverticulitis, developed an incisional hernia (IH) (3cm width) on colostomy site, L2-W1 according to IH-EHS classification and an umbilical IH of 2cm width (EHS classification: M3-W1), after Hartmann reversal.
We planned the abdominal wall repair with R-TAR by drawing on the skin the dimension of the mesh with an overlap of 7cm from the defect, helping us to orient the dissection using transfascial needles.
After the pneumoperitoneum created and the lateral-right sided-docking of Da Vinci Xi, we incised the lateral edge of right posterior rectus sheet (PRS) and dissected the RMP. The incision of the medial edge of the PRS and the identification of the linea alba allows the crossing-over to the contralateral RMP.
We reduced the umbilical IH and dissected completely the left RMP to the flank defect and the Neurovascular Boundles.
We started the division of TA fibers and we dissected the preperitoneal plane beyond the IH sac and to the arcuate line.
We closed the defects with a 0-vloc and the peritoneum with a 3/0-vloc both barbed.
We implanted a 15×30 Progrip selfigripping mesh and we closed the peritoneal-flap with a 2/0-vloc barbed suture.
The patient was discharged in 2 days and any complication were recorded after 30 days.
V-042 ONSTEP - VIDEO REVISION OF THE TECHNIQUE
Authors: Botelho P , Barreira A L , Souto R , Paiva Oliveira G , Onofre S , Luz C 
Published: May 2023

Abstract
ONSTEP is an open preperitoneal approach for inguinal hernia repair. The technique is simple, fast and consists of twelve standardized steps.
The video provides a full step-by-step description of the technique, with some tips and tricks included.
The case refers to a 35-year-old man with a right-sided primary inguinal hernia.
The procedure took around 15 minutes, was uneventful, and no clinically significant postoperative pain was noted. The patient was able to return to work within 2 weeks. After two years of follow-up, the patient remains pain–free and without recurrence.
The ONSTEP technique is an excellent option for inguinal hernia repair, especially for primary unilateral hernias in male patients. The authors believe that this approach should be part of the hernia surgeon´s therapeutic armamentarium.
V-043 Laparoscopic TAPP repair for strangulated femoral hernia
Authors: Correia De Sá T , Basto T , Soares F , Gonçalves Á , Marques I , Barros Da Silva J 
Published: May 2023

Abstract

Aim
To present a case of a strangulated femoral hernia successfully submitted to laparoscopic transabdominal preperitoneal (TAPP) repair and segmental enterectomy.

Material and Methods
Video recording of the surgical procedure and patient clinical files.

Results
A 75-year-old woman with previous medical history of diabetes and dyslipidaemia, went to the Emergency Department with complaints of generalized abdominal pain and absence of bowel moves since the previous day. On physical exam, an incarcerated left femoral hernia was evident. She also presented a renal dysfunction and computed tomography scan revealed a femoral hernia containing a bowel segment with upstream intestinal occlusion. Laparoscopic correction was proposed.
Laparoscopy revealed an ischemic loop of bowel incarcerated in the femoral hernia defect, which was manually reduced. Signs of irreversible ischemia were present, but no perforation was evident. TAPP correction was performed with a polypropylene flat mesh of 37.8g/m2 with wide pores. After, the umbilical incision was extended and an extracorporeal segmental enterectomy with totally mechanical anastomosis was made. The patient had a favourable postoperative course with no complications.

Conclusions
Urgent groin hernia surgery with mesh requiring segmental enterectomy, but without gross peritoneal contamination, is associated with decreased recurrence rates and similar postoperative complications. In experienced centres, laparoscopic surgery may be associated with better results, although randomized multicentre studies are needed.
V-045 PREPERITONEAL APPROACH FOR BILATERAL SPIGELIAN AND RECURRENT LEFT INGUINAL HERNIAS
Authors: Álvarez De Sierra P , Zárate Gómez J , Supelano G , Peinado B , Gil J M , Conde S , López Baena J Á , Fernández Luengas D , Merello J 
Published: May 2023

Abstract
This is a case presentation of a preperitoneal repair of a bilateral Spigelian hernia and a recurrent left inguinal hernia. A 71 year old male patient was admitted in the Emergency department after a 3 hour right quadrant acute pain. On his medical record he had an anterior left inguinal repair (Lichtenstein) 6 months before. The physical examination revealed a bulge on the right lower quadrant. The Spigelian hernia was incarcerated but easily reduced. The CT scan findings include a bilateral Spigelian hernia (bowel content), a small umbilical and a left inguinal omental hernia. The patient did not suffer any other incarceration episodes before the surgery, programmed 10 days later. We present the video of the surgical TEP repair, a preperitoneal access, triple hernia reduction, double 15×20cm polypropilene tailored mesh placement. The patient was discharged on the second postoperative day, and had an uneventful recovery with no recurrence after 3 months followup.
V-048 COMBINED ETEP AND OPEN APPROACH FOR M4 AND L3 VENTRAL HERNIA AFTER COMPLICATED INGUINAL HERNIA REPAIR
Authors: Guevara-Martínez J , Gutierrez E , Chavarrias N , Zapata C , Arteaga P , Prieto F , Fondevila C , Salido S 
Published: May 2023

Abstract
We present the case of a 49 y-o woman with a previous open inguinal hernia repair with a superficial surgical site infection during the immediate postoperative period. She required surgical debridement and negative pressure therapy. Ten months after surgery she persisted with discharge and inflammatory changes. The preoperative CT-scan revealed a misplaced mesh with chronic inflammatory changes in the right inguinal and hypogastric region. An M4 3,5cm diameter defect with a right lateralized 13×5×10cm hernia sac was also observed. A combined open and eTEP approach for mesh removal and retrorectus hernia repair was proposed. Retrorectus dissection began at the left rectus muscle, using two 5 mm trocars for dissection and after crossover a contralateral Hasson trocar was placed. A M4-5W2 and L3 hernia with omental fat and partial bladder sliding into the hernia sac was observed. The right posterior fascia was fibrotic and laterally retracted. After sac contents were fully mobilized, a right partial TAR was necessary in order to close the peritoneum and obtain an adequate dissection for mesh placement. A 25×20cm polypropylene mesh was placed in the retrorectal space. Using a right inguinal incision, previously infected mesh was removed and a silver coated polypropylene mesh was placed below the anterior fascia. The patient was discharged on the third postoperative day and her one month follow up visit was uneventful. We conclude that in this case a hybrid approach can provide an adequate mesh placement via eTEP, with mesh removal by a less invasive approach.
V-050 Abdominal wall reconstruction after resection of dermatofibrosarcoma protuberans
Authors: Morejón Ruiz S , Vaello V 
Published: May 2023

Abstract

Aim
Surgical repair of a complex defect after resection of Dermatofibrosarcoma protuberans.
Materials-methods: Dermatofibrosarcoma protuberans, is an uncommon soft tissue tumor that involves the dermis, subcutaneous fat, and in rare cases, muscle and fascia. We present a 49-year-old patient diagnosed with Dermatofibrosarcoma of the anterior abdominal wall who underwent Mohs surgery to achieve complete resection, resulting in a 12cmx10cm defect in the epigastrium affecting skin, subcutaneous tissue, linea alba and both anterior rectus sheaths.
This tumor is considered an intermediate-grade malignancy with a low likelihood of metastasis but a high local recurrence rate. The optimal treatment is Mohs-micrographic surgery, that allows complete margin assessment and tissue preservation.

Results
Dissection of the retrorectus space is extended caudal to the defect, while dissection proceeded cranially by sectioning the posterior rectus sheath to enter the subxiphoid preperitoneal space. A polypropylene mesh is extended in sublay position. Given the asymmetry of anterior fascia defect, the Chevrel (Welti-Eudel) technique is performed on the left side in order to reconstruct the linea alba. The fascial defect was later covered with an onlay biosynthetic mesh. Finally, closure of the skin was achieved with an O-Zetaplasty ensuring adequate viability of the skin flaps. The patient did not present any postoperative complications.

Conclusions
Resection of locally aggressive tumours such as Dermatofibroma remains the only curative alternative but can pose a reconstructive challenge. Midline reconstruction and closure of large, circular defects in the epigastrium is complicated, requiring deep anatomical knowledge and a combination of different surgical approaches and materials.
V-051 SCOLA TECHNIQUE WITH PERIUMBILICAL MINI-INCISION FOR UMBILICAL HERNIA WITH BIG DIASTASIS RECTI: A CASE REPORT
Authors: Vera Vasquez C A , Gonzalo Prats B , Lupu I , Ye Zhou J , Solans Solerdelcoll M , Gonzalez Lopez J A , Moral Duarte A 
Published: May 2023

Abstract

Background
Diastasis of the rectus abdominis muscles (DRAM) is frequent and may be associated with abdominal wall hernias. In 2017 subcutaneous onlay laparoscopic approach (SCOLA) was described which combines diastasis recti plication and abdominal wall hernia repair without requiring a great incisions nor skin resections.

Objective
To show a video of a SCOLA technique with open periumbilical dissection through 2.5 cm periumbilical mini-incision. The aim is to reduce operative time and to improve the quality of life with good aesthetic results by a minimal invasive procedure.

Method
We report a case of a 39 years old woman with 3 previous caesarian deliveries, diagnosed with umbilical hernia and diastasis recti with a 95mm internal gap. The patient was scheduled electively for a SCOLA technique.

Results
Surgery was performed with no intraoperative complications. Persistent hematic output through drains was seen first 24h postoperatively which required blood transfusion for anemization, but no need for reoperation, correct hemoglobin controls afterward. Small hematoma detected in 1st month control, with correct resolution on 4th month control. No recurrence of umbilical hernia nor diastasis recti observed during this short follow-up.

Conclusion
SCOLA technique has been proven to be a reproductive and secure technique for those patients with DRAM associated with abdominal wall hernia that do not require nor need skin resection or great incisions. The aim of the periumbilical dissection through mini-incision is to decrease surgical time. One must consider the risk of bleeding or seroma associated with the extensive dissection in cases with great diastasis gap.
Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies
Authors: Young Alexandra L , Vogel Jacob W , Robinson John L , McMillan Corey T , Ossenkoppele Rik , Wolk David A , Irwin David J , Elman Lauren , Grossman Murray , Lee Virginia M Y , Lee Edward B , Hansson Oskar 
Published: May 2023

Abstract
TAR DNA-binding protein-43 (TDP-43) accumulation is the primary pathology underlying several neurodegenerative diseases. Charting the progression and heterogeneity of TDP-43 accumulation is necessary to better characterize TDP-43 proteinopathies, but current TDP-43 staging systems are heuristic and assume each syndrome is homogeneous. Here, we use data-driven disease progression modelling to derive a fine-grained empirical staging system for the classification and differentiation of frontotemporal lobar degeneration due to TDP-43 (FTLD-TDP, n = 126), amyotrophic lateral sclerosis (ALS, n = 141) and limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) with and without Alzheimer’s disease (n = 304).
The data-driven staging of ALS and FTLD-TDP complement and extend previously described human-defined staging schema for ALS and behavioural variant frontotemporal dementia. In LATE-NC individuals, progression along data-driven stages was positively associated with age, but negatively associated with age in individuals with FTLD-TDP. Using only regional TDP-43 severity, our data driven model distinguished individuals diagnosed with ALS, FTLD-TDP or LATE-NC with a cross-validated accuracy of 85.9%, with misclassifications associated with mixed pathological diagnosis, age and genetic mutations. Adding age and SuStaIn stage to this model increased accuracy to 92.3%. Our model differentiates LATE-NC from FTLD-TDP, though some overlap was observed between late-stage LATE-NC and early-stage FTLD-TDP. We further tested for the presence of subtypes with distinct regional TDP-43 progression patterns within each diagnostic group, identifying two distinct cortical-predominant and brainstem-predominant subtypes within FTLD-TDP and a further two subcortical-predominant and corticolimbic-predominant subtypes within ALS. The FTLD-TDP subtypes exhibited differing proportions of TDP-43 type, while there was a trend for age differing between ALS subtypes. Interestingly, a negative relationship between age and SuStaIn stage was seen in the brainstem/subcortical-predominant subtype of each proteinopathy. No subtypes were observed for the LATE-NC group, despite aggregating individuals with and without Alzheimer’s disease and a larger sample size for this group.
Overall, we provide an empirical pathological TDP-43 staging system for ALS, FTLD-TDP and LATE-NC, which yielded accurate classification. We further demonstrate that there is substantial heterogeneity amongst ALS and FTLD-TDP progression patterns that warrants further investigation in larger cross-cohort studies.
Modelling and analysis of parameters of vacuum tube solar collector with U-shaped tube for different climates
Authors: Smaisim Ghassan Fadhil , Abed Azher M , Hadrawi Salema K , Jahanbin Farnaz 
Published: May 2023

Abstract
In this study, based on the energy balance for different components of a double-layered vacuum-tube solar collector with a U-tube, the thermal performance of the collector unit is investigated separately using an analytical and quasi-dynamic method. The model used in this study determines the temperature distribution in longitudinal and radial directions. In this research, the effects of physical parameters and heat transfer including the size of the collector, thermal-loss coefficient, absorption coefficient, mass flow and thermal resistance of the air layer under different climate conditions have been evaluated on the performance of the vacuum-tube collector. The results showed that by increasing the diameter of the tube with constant length, the annual thermal efficiency of the collector increased. Also, in a fixed-diameter tube, with increasing tube length, the annual efficiency increases, but this increase is meagre for lengths of &gt;1.5 m. The optimal mass flow rate for maximum efficiency has been obtained for cities with different climates. According to the results, the optimal flow for different climates has different values that can be optimized as a relationship between the average solar radiation annually as a symbol of temperature and flow.
Advanced DC–DC converter topologies for solar energy harvesting applications: a review
Authors: Sutikno Tole , Samosir Ahmad Saudi , Aprilianto Rizky Ajie , Purnama Hendril Satrian , Arsadiando Watra , Padmanaban Sanjeevikumar 
Published: May 2023

Abstract
In this study, the advanced topologies of a DC–DC converter for applications involving the harvesting of solar energy are discussed. This work’s primary contribution is a guide for choosing the most effective topology for a DC–DC converter when developing solar energy collection systems. Several topologies of a DC–DC converter for solar energy harvesting applications are compared in terms of the range of power levels they can oversee, the complexity of the underlying hardware, the cost of implementation, the tracking efficiency and the overall efficiency of the converter. This article explains five innovative approaches for adapting boost converters to function as standard DC–DC converters to capture solar energy, consisting of (i) voltage-multiplier cell, (2) coupled inductor, (3) coupled inductor and switch capacitor, (4) cascaded topology and (5) voltage-lift technique. Because of the boost converter’s restrictions, it is necessary to deliver high performance. The comparison findings demonstrate that the voltage-lift-based boost-converter topology performs more effectively than the alternatives. In conclusion, the information presented in this paper can be utilized when developing solar energy collection systems to determine the sort of direct current to direct current converter that will be most effective.
Efficacy of Cognitive-Behavioral Therapy Targeting Severe Fatigue Following Coronavirus Disease 2019: Results of a Randomized Controlled Trial
Authors: Kuut Tanja A , Müller Fabiola , Csorba Irene , Braamse Annemarie , Aldenkamp Arnoud , Appelman Brent , Assmann-Schuilwerve Eleonoor , Geerlings Suzanne E , Gibney Katherine B , Kanaan Richard A A , Mooij-Kalverda Kirsten , Olde Hartman Tim C , Pauëlsen Dominique , Prins Maria , Slieker Kitty , van Vugt Michele , Keijmel Stephan P , Nieuwkerk Pythia , Rovers Chantal P , Knoop Hans 
Published: May 2023

Abstract

Background
Severe fatigue following coronavirus disease 2019 (COVID-19) is prevalent and debilitating. This study investigated the efficacy of cognitive-behavioral therapy (CBT) for severe fatigue following COVID-19.

Methods
A multicenter, 2-arm randomized controlled trial was conducted in the Netherlands with patients being severely fatigued 3–12 months following COVID-19. Patients (N = 114) were randomly assigned (1:1) to CBT or care as usual (CAU). CBT, targeting perpetuating factors of fatigue, was provided for 17 weeks. The primary outcome was the overall mean difference between CBT and CAU on the fatigue severity subscale of the Checklist Individual Strength, directly post-CBT or CAU (T1), and after 6 months (T2). Secondary outcomes were differences in proportions of patients meeting criteria for severe and/or chronic fatigue, differences in physical and social functioning, somatic symptoms, and problems concentrating between CBT and CAU.

Results
Patients were mainly nonhospitalized and self-referred. Patients who received CBT were significantly less severely fatigued across follow-up assessments than patients receiving CAU (−8.8 [95% confidence interval {CI}, −11.9 to −5.8]); P &lt; .001), representing a medium Cohen's d effect size (0.69). The between-group difference in fatigue severity was present at T1 (−9.3 [95% CI, −13.3 to −5.3]) and T2 (−8.4 [95% CI, −13.1 to −3.7]). All secondary outcomes favored CBT. Eight adverse events were recorded during CBT, and 20 during CAU. No serious adverse events were recorded.

Conclusions
Among patients, who were mainly nonhospitalized and self-referred, CBT was effective in reducing fatigue. The positive effect was sustained at 6-month follow-up.

Clinical Trials Registration
Netherlands Trial Register NL8947.
Assessing the impact of piercing-sucking pests on greenhouse-grown industrial hemp (Cannabis sativa L.)
Authors: Pulkoski Melissa , Burrack Hannah 
Published: May 2023

Abstract
Cannabis sativa or hemp, defined as &lt;0.3% total tetrahydrocannabinol (THC), is a specialty crop in the United States, of particular interest among growers in the southeastern United States to replace tobacco production. Tetranychus urticae (twospotted spider mite), Aculops cannabicola (hemp russet mite), Polyphagotarsonemus latus (broad mites), and Phorodon cannabis (cannabis aphids) are considered the most significant pests in greenhouse grown hemp. Mite and aphid injury can cause cupping and yellowing of leaves, resulting in leaf drop, and reduced flower and resin production. We sought to understand the effects of feeding by T. urticae and Myzus persicae (green peach aphid), as a proxy for P. cannabis, on the concentration of economically significant cannabinoids through a series of experiments on greenhouse grown plants. First, we compared the variability of chemical concentrations in samples collected from individual plants versus pooled samples from 5 plants, and found that chemical concentrations in single plants were similar to those in pooled plant samples. Next, we compared chemical concentrations prior to arthropod infestation and post infestation. When evaluating the mite feeding damage in 2020, cannabinoids in plants infested with high densities of T. urticae increased more slowly than in uninfested control plants or plants infested with low T. urticae densities. In 2021, the concentration of tetrahydrocannabinol did not differ significantly between treatments. Cannabidiol increased more slowly in plants with low T. urticae densities when compared to uninfested controls but did not differ from the high T. urticae densities 14 days after infestation.