bluuebunny/crossref_metadata_2025_split huggingface dataset:
OMIP‐088: Twenty‐target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver
Authors: Birrer Fabienne , Brodie Tess , Stroka Deborah 
Published: January 2023

AbstractThe purpose of this 20‐target imaging mass cytometry (IMC) panel is to identify the main cell types in formalin fixed paraffin embedded (FFPE) mouse liver tissue with the Hyperion™ mass cytometer from Standard BioTools (formerly Fluidigm). The antibody panel includes markers to identify hepatocytes (E‐cadherin, HNF4α (hepatocyte nuclear factor 4 alpha), Arginase‐1), liver sinusoidal endothelial cells (LSECs; CD206), Kupffer cells (F4/80, CD206), neutrophils (Ly6G, CD11b), bone marrow derived myeloid cells (BMDMs; CD11b), cholangiocytes (E‐cadherin high), endothelial cells (CD31, α‐SMA), plasmacytoid dendritic cells (CD317), B cells (CD19), T cells (CD3e, CD4, CD8a), NK cells (CD161) as well markers of cell activation (CD44, CD74), proliferation (Ki‐67) and to aid in cell segmentation (Pan‐Actin, E‐cadherin, histone H3). The panel has been tested in other mouse tissues, namely the spleen, colon and lung, and therefore is likely to work across various mouse FFPE samples of interest. It has not been tested using human samples, frozen samples or in suspension mass cytometry because FFPE treatment profoundly changes epitope conformation. In summary, this panel is a powerful tool for pre‐clinical research to determine cellular abundance and spatial distribution within mouse tissues and serves as a scaffold, to which more targets can be added for project specific requirements.
Porous Magnesium Oxide by Twin Polymerization: From Hybrid Materials to Catalysis
Authors: Scharf Sebastian , Notz Sebastian , Thomas Rico , Mehring Michael , Tegenkamp Christoph , Formánek Petr , Hübner René , Lang Heinrich 
Published: January 2023

AbstractTwin monomers [Mg(2‐OCH2‐cC6H4O)][L]0.8 (2, L=diglyme) and [Mg(2‐OCH2‐cC6H4O)][L]0.66 (3, L=tmeda) form by their thermal polymerization interpenetrating organic‐inorganic hybrid materials in a straightforward manner. Carbonization (Ar) followed by calcination gave porous MgO (2: surface area 200 m2 g−1, 3: 400 m2 g−1), which showed in catalytic studies towards Meerwein‐Ponndorf‐Verley reductions excellent yields and complete conversions for cyclohexanone and benzaldehyde. However, with crotonaldehyde a mixture of C4–C8 compounds was obtained. When MgO was exposed to air then primarily crotyl alcohol was formed. The range of applications could be easily extended by twin polymerization of 3 in presence of [Cu(O2CCH2O(CH2CH2O)2Me)2] (4) or [Ag(O2CCH2‐cC4H3S)(PPh3)] (5), resulting in the formation of nanoparticle‐decorated porous CuO@MgO or Ag@MgO materials, which showed high catalytic reactivity towards the reduction of methylene blue.
tBu4NCl/K2S2O8 System Induced C‐2 Functionalization of 8‐Aminoquinoline Amides with Primary Alcohols
Authors: Zhang Kaixin , Xu Jianxiong , Xiao Jinxiang , Zhong Ronglin , Li Jizhen 
Published: January 2023

AbstractA metal and light‐free Minisci‐type acylation approach of 8‐aminoquinoline amides with general primary alcohols was demonstrated under tBu4NCl/K2S2O8 system. Simultaneously, the C2−H alkylation can be realized by accident for special benzyl alcohols bearing strong electron‐donating groups. Most N‐heterocycles were also compatible to afford corresponding acylated products. Furthermore, the mechanism investigation reveals that chlorine radical induced the original ketyl radical generation through abstracting the α‐C−H from the alcohols, then underwent nucleophilic carbon‐centered radicals addition, deprotonation, and oxidation to provide the target acylation products.
Situation updating during discourse comprehension recruits right posterior portion of the multiple‐demand network
Authors: Yang XiaoHong , Lin Nan , Wang Lin 
Published: January 2023

AbstractDiscourse comprehension involves the construction of a mental representation of the situation model as well as a continuous update of this representation. This mental update is cognitively demanding and likely engages the multiple‐demand network. However, there is little evidence for the involvement of the multiple‐demand network during situation updating. In this study, we used fMRI to test whether situation updating based on the change of spatial location activated the multiple‐demand network. In a discourse comprehension task, readers read two‐sentence discourses in which the second sentence either continues or introduces a shift of the spatial location information presented in the first sentence. Compared to situation continuation, situation updating reliably activated the right superior parietal lobule. This area is a part of the multiple‐demand network as defined by a digit N‐back localizer task and locates within the dorsal attention network as defined in the previous study by Yeo et al. in 2011. Our results provide evidence for the reliable involvement of a specific area of the multiple‐demand network in situation updating during high‐level discourse processing.
The effects of thermal radiation on unsteady MHD free convective flow through the porous medium between two vertical plates with Hall effects
Authors: Nagaraju L. , Naikoti Kishan 
Published: January 2023

AbstractThe effects of thermal radiation and Hall current on magnetohydrodynamic free convection three‐dimensional flow in a vertical channel filled with a porous medium have been studied. We consider an incompressible viscous and electrically conducting incompressible viscous fluid in a parallel plate channel bounded by a loosely packed porous medium. The fluid is driven by a uniform pressure gradient parallel to the channel plates, and the entire flow field is subjected to a uniform inclined magnetic field of strength inclined at an angle of inclination with the normal to the boundaries in the transverse xy‐plane. The temperature of one of the plates varies periodically, and the temperature difference between the plates is high enough to induce radiative heat transfer. The effects of various parameters on the velocity profiles, the skin friction, the temperature field, and the rate of heat transfer in terms of their amplitude and phase angles are shown graphically.
Near constant groundwater recharge efficiency under global change in a central European catchment
Authors: Riedel Thomas , Weber Tobias K. D. , Bergmann Axel 
Published: January 2023

AbstractThe fraction of precipitation that infiltrates soils and subsequently becomes recharge is one of the principle components of an unconfined aquifer's water budget (this fraction is here termed recharge efficiency). Here we tested how recharge efficiency will respond to climate change including a possible plant physiological response to climate change (e.g., stomatal closure; increasing leaf area) in a catchment used for drinking water production in western Germany. To this end we used a soil water model (HYDRUS‐1D) forced with climate data spanning the time period from 1971 to 2099. Three different vegetation types were considered: turf grass representing the primary infiltration sites within residential areas; maize representing the main crop on agriculturally used land; and beech representing the forested parts of the catchment. We found that, the positive effects of climate change on recharge efficiency (more rain during the main recharge season in winter, less crop water demand due to faster plant ripening in spring and summer, increased plant water use efficiency, reduced global radiation as cloud density increases) were not completely compensated by the negative effects (less precipitation, higher leaf area index and increasing vapour pressure deficit in summer season) at our study site. Because total annual precipitation increased slightly until the end of the 21th century, changes in the amount of total annual recharge were also positive, though moderate (up to +20% change in the period 2071–2099 as compared to 1970–2000). The results of this study will be helpful for water authorities managing water rights under the perspective of a changing climate. In the future, our study site is expected to receive sufficient recharge from precipitation to maintain current rates of groundwater withdrawal for public water supply and irrigation. Thus, the region's agriculture sector may become a ‘global warming winner,’ when cropping in other regions in Europe may increasingly suffer from drying conditions during the growing season.
Spatial Chemoproteomics for Mapping the Active Proteome
Authors: Swenson Colin S. , Smitha Pillai Kavya , Carlos Anthony J. , Moellering Raymond E. 
Published: January 2023

AbstractFunctional regulation of cell signaling through dynamic changes in protein activity state as well as spatial organization represent two dynamic, complex, and conserved phenomena in biology. Seemingly separate areas of ‐omics method development have focused on building tools that can detect and quantify protein activity states, as well as map sub‐cellular and intercellular protein organization. Integration of these efforts, through the development of chemical tools and platforms that enable detection and quantification of protein functional states with spatial resolution provide opportunities to better understand heterogeneity in the proteome within cell organelles, multi‐cellular tissues, and whole organisms. This review provides an overview of and considerations for major classes of chemical proteomic probes and technologies that enable protein activity mapping from sub‐cellular compartments to live animals.
Chinese aid and crime: Evidence from Africa
Authors: Appiah‐Kubi Michael , Jarrett Jeneshia 
Published: January 2023

AbstractWe study how the allocation of resources impacts localised crime rates. Recent studies on the effects of Chinese aid in Africa have increased rapidly, and this paper contributes by showing the mechanism by which aid increases crime. Using a geo‐referenced dataset of subnational allocation of Chinese projects, geographically matched with 145 701 respondents of four rounds of Afrobarometer surveys from 36 African countries, we use a difference‐in‐difference‐in‐difference (DDD) approach and an instrumental variable (IV) identification strategy to account for endogeneity and capture the effect of living near projects under implementation before or after a survey against those with no projects. We find that Chinese aid projects significantly increased crime rates in the immediate locations where the projects were implemented. The main channel of effect is the increased local economic activities leading to the availability of employable opportunities. There is a similar but smaller magnitude of the effect regarding projects funded by other donor agencies.
Optimization of sowing date for spring maize in China's loess plateau based on presowing temperature and soil water content
Authors: Shen Hongzheng , Xu Yue , Wang Yue , Cheng Gang , Li Shilei , Jiang Kongtao , Ma Xiaoyi 
Published: January 2023

AbstractBackgroundThe sowing date of spring maize in China's Loess Plateau is often restricted by the presowing temperature and soil water content (SWC). The effective measurement of the effects of presowing temperature and SWC on the sowing date is a major concern for agricultural production in this region. In this paper, we considered the average daily air temperature of ˃10 °C in the 7 days before sowing. The Decision Support System for Agrotechnology Transfer (DSSAT) model was used to simulate a spring maize yield under distinct combinations of SWC and sowing date for 51 years (1970–2020). Subsequently, through the cumulative probability distribution function, the contribution of presowing SWC to the spring maize yield was quantified, and the optimal sowing date of spring maize in each production location was determined.ResultsThe results revealed that the daily average temperature of ˃10 °C for 7 days consecutively can be used effectively as the basis for the simulation of spring maize sowing date. The presowing SWC affected the spring maize yield but did not change the optimal sowing date. When the SWC of each study site is about 70% of the field capacity, Wenshui and Yuanping can properly delay sowing, and Lin county can sow early to obtain a higher yield.ConclusionThis study provides an effective approach for optimizing presowing soil moisture management and the sowing date of spring maize in the semiarid regions of the Loess Plateau. © 2023 Society of Chemical Industry.
Team Consistency in Reducing Operative Time in Head and Neck Surgery with Microvascular Free Flap Reconstruction
Authors: Sawaf Tuleen , Renslo Bryan , Virgen Celina , Farrokhian Nathan , Yu Katherine M. , Gessert Thomas G. , Jackson Cree , O'Neill Katie , Sperry Bethany , Kakarala Kiran 
Published: January 2023

Objective(s)To evaluate the impact of consistent surgical teams on procedure duration in head and neck free tissue transfer, and to evaluate the length of stay and readmission rates with consistent teams.MethodsA retrospective chart review of head and neck microvascular reconstruction by a single surgeon between August 2017 and November 2021 was performed. Procedure duration, wound complications, length of stay, and 30‐day readmissions were analyzed. One circulating nurse (CN) and surgical technologist (ST) were considered “consistent” due to their prior work with the primary surgeon. All others were considered “ad hoc.” Teams were “Consistent CN + ST,” “Consistent ST,” “Consistent CN,” or “Ad hoc.” Procedure duration between groups was compared via analysis of variance. Multivariate linear regression was performed to predict procedure duration.ResultsA total of 135 patients were included. Age, sex, and American Society of Anesthesiologists status did not significantly differ across groups (p = 0.963; p = 0.467; p = 0.908, respectively). The mean procedure duration was 339.3 min and differed significantly across all groups (p = 0.006, Cohen d = 0.32). Compared to the Ad hoc group, consistent teams demonstrated significant reductions in mean procedure duration (Consistent CN + ST: 58.4 min, p = 0.001, Cohen d = 0.67; Consistent ST: 51.6 min, p = 0.013, Cohen d = 0.61; Consistent CN: 44.5 min, p = 0.031, Cohen d = 0.52). Controlling for other factors, the ad hoc team predicted increased procedure duration on multivariate analysis ( 57.38, 19.92–94.85, p < 0.003). Wound complications, length of stay, and readmission rates did not differ significantly across groups (p = 0.940; p = 0.174; p = 0.935, respectively).ConclusionConsistent CN and ST improve operative efficiency in head and neck‐free tissue transfer. Future studies may evaluate the impact of team consistency on complications, physician burnout, and health systems costs.Level of Evidence3 Laryngoscope, 133:2154–2159, 2023
When to invest in electric vehicles under dual credit policy: A real options approach
Authors: Liu Feng , Tan Yingshuang , Sarkar Sudipto , Zhang Xueqing , Huang Xingjun 
Published: January 2023

AbstractThis research aims to investigate traditional vehicle manufacturers' green technology investment theory under dual credit policy from the perspective of real options, overcoming earlier investigations of this issue that considered it only from a stability or single uncertainty perspective. An analytical real options model was first provided for traditional automaker investment. Then we solved the analytical solution for the electric vehicle investment threshold based on the uncertainty of credit price and fuel vehicle market scenarios. The optimal electric vehicle investment timing is demonstrated using numerical simulation. Results show that (1) when the fuel vehicle market demand falls to a certain level, automakers will choose to make electric vehicle investments regardless of how the credit price changes in the market; (2) the effect of volatility on the investment threshold depends on the covariance or correlation coefficient; (3) the numerical simulation results revealed that the credit price drift rate, risk‐free rate, correlation parameters, and electric vehicle production cost all have a positive impact on the electric vehicle investment region, whereas the drift rate of fuel vehicle and electric vehicle production cost have a negative impact. These results can be used to make theoretical conclusions about electric vehicle investments.
Democratization from below: Civil society in Tajikistan
Authors: Fisher Melton Julie 
Published: January 2023

AbstractA decade ago an exploration of civil society in South Africa, Tajikistan and Argentina highlighted its role in supporting democratization. Despite continuing global autocratic trends since then, South Africa and Argentina have remained vibrant democracies with strong civil societies. Tajikistan, in contrast, remains autocratic, and civil society has apparently weakened in recent years. However, at the grassroots level a combination of traditional grassroots organizations and Internet organizing provides a more complex picture of the relationships between local participation, ties with other civil society organizations, democratization and development. The purpose of this paper is to highlight both these relationships and the contrast between local democratization and national autocracy.
MMR vaccination timing and long‐term immunity among childhood cancer survivors
Authors: Speckhart Susan Ashley 
Published: January 2023

AbstractLong‐term seroprotection against the measles and mumps viruses has not been reported in childhood cancer survivor (CCS) who received two‐lifetime doses of the measles, mumps, and rubella (MMR) vaccine. We performed a retrospective study of measles and mumps titers among 55 CCS who received standard chemotherapy and two MMR vaccinations at any time. Over 75% of CCS who received at least one MMR prior to their cancer diagnosis had a negative or equivocal titer to measles or mumps. In contrast, all CCS who received the MMR series following their cancer treatment demonstrated long‐term seroprotection to both viruses at a mean of 8.2 years after their last vaccination.
Barriers to medication adherence among adolescents and young adults with cancer
Authors: McGrady Meghan E. , Ketterl Tyler G. , Norris Robin E. , Perentesis John P. , Pettee Daniel , Mara Constance A. , Breen Gabriella , Pai Ahna L. H. 
Published: January 2023

AbstractBackgroundAdherence promotion is a critical component of adolescent and young adult (AYA) cancer care, but predictors of nonadherence that could be targeted in intervention efforts remain largely unknown. The purpose of this multi‐site longitudinal observational study was to examine the relationship between barriers and medication adherence among AYAs with cancer.ProcedureSixty‐five AYAs (ages 15–24 years; mean age = 18.97 years, SD = 2.51; Mmean time since diagnosis = 1.42 years, SD = 1.95) with newly diagnosed or relapsed cancer completed self‐report measures of barriers and adherence at quarterly study visits and used an electronic adherence monitoring device for 12 months. Longitudinal mixed effects models were used to examine our primary hypothesis that greater barriers are related to lower adherence over time. Descriptive statistics were used to explore our secondary aim of describing the frequency and patterns of barriers endorsed by AYAs with cancer.ResultsAfter controlling for covariates (time, medication type, race, ethnicity, diagnosis, time since diagnosis), a greater number of barriers was associated with lower electronically monitored (β = −5.99, p = .005) and self‐reported (β = −1.92, p < .001) adherence. The specific barriers endorsed by AYAs differed across participants, and the majority of AYAs endorsed an entirely different pattern of barriers than any other AYA in the study.ConclusionBarriers are associated with nonadherence and may be a promising target for intervention. Individual variability across barriers, however, suggests that tailoring may be necessary, and a promising next step is to explore personalized approaches to adherence promotion.
Safety‐critical control for robotic systems with uncertain model via control barrier function
Authors: Zhang Sihua , Zhai Di‐Hua , Xiong Yuhan , Lin Juncheng , Xia Yuanqing 
Published: January 2023

AbstractUsually, it is difficult to build accurate dynamic models for real robots, which makes safety‐critical control a challenge. In this regard, this article proposes a double‐level framework to design safety‐critical controller for robotic systems with uncertain dynamics. The high level planner plans a safe trajectory for low level tracker based on the control barrier function (CBF). First, the high level planning is done independently of the dynamic model by quadratic programs subject to CBF constraint. Afterward, a novel method is proposed to learn the uncertainty of drift term and input gain in nonlinear affine‐control system by a data‐driven Gaussian process (GP) approach, in which the learning result of uncertainty in input gain is associated with CBF. Then, a Gaussian processes‐based control barrier function (GP‐CBF) is designed to guarantee the tracking safety with a lower bound on the probability for the low level tracker. Finally, the effectiveness of the proposed framework is verified by the numerical simulation of UR3 robot.
Highly Active and Recyclable CuxFe3‐xO4 NPs for Selective Oxidation of Benzyl Alcohol using TBHP as an Oxidant
Authors: Arjunan Ayyappan , Manikandan Marimuthu , Vijayaraghavan Rajagopalan , Sangeetha Palanivelu 
Published: January 2023

AbstractHerein, we report the synthesis of CuxFe3‐xO4 nanoparticles (NPs) via a novel, facile, cost‐effective, and eco‐benign method using a water‐soluble egg‐white. The characterization studies confirmed that the fabricated CuxFe3‐xO4 NPs are crystalline and possess super‐paramagnetic behavior. The fabricated magnetic CuxFe3‐xO4 NPs also exhibited excellent catalytic performance towards the selective oxidation of benzyl alcohol to benzaldehyde using tetra‐butyl hydroperoxide (TBHP) as an oxidant under solvent‐free conditions. It was found that the addition of egg‐white during the synthesis significantly enhanced both the crystallinity and catalytic activity. Among the prepared ratios, Cu1.5Fe1.5O4 demonstrated the highest conversion (>73 %) and complete selectivity (100 %) to benzaldehyde under lenient oxidation conditions. The novelty of the work lies in achieving the magnetically recoverable CuxFe3‐xO4 NPs in the absence of any base or other organic reagents and is highly selective for the production of benzaldehyde under the mild reaction condition.
Metallic MoO2 as a Highly Selective Catalyst for Electrochemical Nitrogen Fixation to Ammonia under Ambient Conditions
Authors: N. K Muhammed Safeer , Sathiskumar Chinnusamy , John Neena S. 
Published: January 2023

AbstractThe development of earth‐abundant and non‐noble based metal catalysts for electrochemical nitrogen reduction towards sustainable ammonia production from N2 and H2O in the ambient atmosphere holds immense potential in realizing an alternate route to energy‐intensive Haber‐Bosch process. Herein, we have employed highly conductive MoO2 synthesized by hydrothermal route as an electrocatalyst for ammonia generation. The MoO2 catalyst was employed for electrochemical nitrogen reduction in N2 saturated 0.1 m HCl electrolyte in a two‐compartment cell. Ammonia yield rate of 2.30 μg h−1 mg−1cat and 2.40 % Faradaic efficiency has been obtained at a potential of −0.3 V vs. RHE. The MoO2 catalyst is selective for ammonia generation without any hydrazine formation. The metallic nature of MoO2 catalyst assists in achieving comparable activity for the electrochemical nitrogen reduction. The above catalyst has the potential for providing better ammonia yield rate by combining or doping with other active elements.