bluuebunny/crossref_metadata_2025_split huggingface dataset:
A porcine study of ultrasound-guided versus fluoroscopy-guided placement of endovascular balloons in the inferior vena cava (REBOVC) and the aorta (REBOA)
Authors: Wikström Maria B , Åström Jens , Stene Hurtsén Anna , Hörer Tal M , Nilsson Kristofer F 
Published: May 2023

ObjectivesIn fluoroscopy-free settings, alternative safe and quick methods for placing resuscitative endovascular balloon occlusion of the aorta (REBOA) and resuscitative endovascular balloon occlusion of the inferior vena cava (REBOVC) are needed. Ultrasound is being increasingly used to guide the placement of REBOA in the absence of fluoroscopy. Our hypothesis was that ultrasound could be used to adequately visualize the suprahepatic vena cava and guide REBOVC positioning, without significant time-delay, when compared with fluoroscopic guidance, and compared with the corresponding REBOA placement.MethodsNine anesthetized pigs were used to compare ultrasound-guided placement of supraceliac REBOA and suprahepatic REBOVC with corresponding fluoroscopic guidance, in terms of correct placement and speed. Accuracy was controlled by fluoroscopy. Four intervention groups: (1) fluoroscopy REBOA, (2) fluoroscopy REBOVC, (3) ultrasound REBOA and (4) ultrasound REBOVC. The aim was to carry out the four interventions in all animals. Randomization was performed to either fluoroscopic or ultrasound guidance being used first. The time required to position the balloons in the supraceliac aorta or in the suprahepatic inferior vena cava was recorded and compared between the four intervention groups.ResultsUltrasound-guided REBOA and REBOVC placement was completed in eight animals, respectively. All eight had correctly positioned REBOA and REBOVC on fluoroscopic verification. Fluoroscopy-guided REBOA placement was slightly faster (median 14 s, IQR 13–17 s) than ultrasound-guided REBOA (median 22 s, IQR 21–25 s, p=0.024). The corresponding comparisons of the REBOVC groups were not statistically significant, with fluoroscopy-guided REBOVC taking 19 s, median (IQR 11–22 s) and ultrasound-guided REBOVC taking 28 s, median (IQR 20–34 s, p=0.19).ConclusionUltrasound adequately and quickly guide the placement of supraceliac REBOA and suprahepatic REBOVC in a porcine laboratory model, however, safety issues must be considered before use in trauma patients.Level of evidenceProspective, experimental, animal study. Basic science study.
Measuring neutron capture cross sections of radioactive nuclei
Authors: Dillmann Iris , Kester Oliver , Baartman Richard , Chen Alan , Junginger Tobias , Herwig Falk , Kaltchev Dobrin , Lennarz Annika , Planche Thomas , Ruiz Chris , Vassh Nicole 
Published: May 2023

AbstractMeasuring neutron capture cross sections of radioactive nuclei is a crucial step towards a better understanding of the origin of the elements heavier than iron. For decades, the precise measurement of direct neutron capture cross sections in the “stellar” energy range (eV up to a few MeV) was limited to stable and longer-lived nuclei that could be provided as physical samples and then irradiated with neutrons. New experimental methods are now being developed to extend these direct measurements towards shorter-lived radioactive nuclei ($$t_{1/2}<$$

t

1
/
2

<

1 y). One project in this direction is a low-energy heavy-ion storage ring coupled to the ISAC facility at TRIUMF, Canada’s accelerator laboratory in Vancouver BC, which has a compact neutron source in the ring matrix. Such a pioneering facility could be built within the next 10 years and store a wide range of radioactive ions provided directly from the existing ISOL facility, allowing for the first time to carry out direct neutron capture measurements on short-lived isotopes in inverse kinematics.
Updated and novel limits on double beta decay and dark matter-induced processes in platinum
Authors: Broerman B. , Laubenstein M. , Nagorny S. S. , Nisi S. , Song N. , Vincent A. C. 
Published: May 2023

AbstractA 510 day long-term measurement of a 45.3 g platinum foil acting as the sample and high voltage contact in an ultra-low-background high purity germanium detector was performed at Laboratori Nazionali del Gran Sasso (Italy). The data was used for a detailed study of double beta decay modes in natural platinum isotopes. Limits are set in the range $${\mathcal {O}}(10^{14}{-} 10^{19})$$

O
(

10
14

-

10
19

)

years (90% C.L.) for several double beta decay transitions to excited states confirming, and partially extending existing limits. The highest sensitivity of the measurement, greater than $$10^{19}$$

10
19

years, was achieved for the two neutrino and neutrinoless double beta decay modes of the isotope $$^{198}$$

198

Pt. Additionally, novel limits for inelastic dark matter scattering on $$^{195}$$

195

Pt are placed up to mass splittings of approximately 500 keV. We analyze several techniques to extend the sensitivity and propose a few approaches for future medium-scale experiments with platinum-group elements.
Regularizing the JNW and JMN naked singularities
Authors: Pal Kunal , Pal Kuntal , Roy Pratim , Sarkar Tapobrata 
Published: May 2023

AbstractWe extend the method of Simpson and Visser (SV) of regularizing a black hole spacetime, to cases where the initial metric represents a globally naked singularity. We choose two particular geometries, the Janis–Newman–Winicour (JNW) metric representing the solution of an Einstein-scalar field system, and the Joshi–Malafarina–Narayan (JMN) metric that represents the asymptotic equilibrium configuration of a collapsing star supported by tangential pressures as the starting configuration. We illustrate several novel features for the modified versions of the JNW and JMN spacetimes. In particular, we show that, depending on the values of the parameters involved the modified JNW metric may represents either a two way traversable wormhole or it may retain the original naked singularity. On the other hand, the SV modified JMN geometry is always a wormhole. Particle motion and observational aspects of these new geometries are investigated and are shown to posses interesting features. We also study the quasinormal modes of different branches of the regularized spacetime and explore their stability properties.
Tri-vector deformations on compact isometries
Authors: Musaev Edvard T. , Petrov Timophey 
Published: May 2023

AbstractClassical Yang–Baxter equation governing bi-vector deformations of 10d supergravity is known to have no solutions along non-abelian compact isometries. By providing explicit examples we show that this is in contrast to generalized Yang–Baxter equation governing tri-vector deformations of 11d supergravity. We present deformations of the AdS$${}_7\times \mathbb {S}^4$$

7

×

S

4

and flat backgrounds with isometries generated by Killing vectors of a sphere. Isometries of the AdS space-time are preserved by such deformations.
Entanglement dynamics and population inversion of a two-qubit system in two cavities coupled with optical fiber in the presence of two-photon transition
Authors: Musavi S. A. S. , Tavassoly M. K. , Salimian S. 
Published: May 2023

In this paper, the entanglement between two qubits that exist in two distinct cavities which are connected by an optical fiber is investigated by using the concurrence, while two-photon transitions and Kerr medium effect are also considered. Each cavity contains a qubit and a single-mode quantized field. The appearance of entanglement between the two qubits in the separate cavities originates from the presence of optical fiber. The obtained numerical results of the considered system show that, if the Kerr medium is large enough, the initial values of entanglement between the two qubits (which may have the maximum possible value, i.e. 1) can be approximately protected from the large amplitude fluctuations, so that acceptable stability is created. Also, qubit-field coupling and detuning effects are investigated and it is observed that symmetric coupling results in more stability of entanglement. Eventually, atomic population inversion is also studied and it is observed that it is controllable by considering different parameters.
Review and tectonic interpretation of Precambrian Avalonia
Authors: Keppie John Duncan , Keppie Duncan Fraser 
Published: May 2023

Abstract

Avalonia, defined by its distinctive uppermost Ediacaran–Ordovician overstep sequence, extends from New England through Atlantic Canada to Wales. It unconformably overlies: (1) parts of one cratonic Neoproterozoic arc that which records several pulses at: 760–730 Ma, 680–600 Ma and 580–540 Ma; (2) an 800–760 Ma passive margin sequence; and (3)
c.
976 Ma isolated plutons, possibly basement. Comparisons with modern arc dimensions suggest the dip of the Benioff Zone ranged from
c.
22° W in Newfoundland to
c.
52–67° elsewhere. A 600–580 Ma hiatus in arc magmatism in Cape Breton Island is attributed to overriding an oceanic plateau, leading to a 15° decrease in the dip of the Benioff Zone. The Collector magnetic anomaly along the Grand Banks and the Minas Fault is inferred to mark the Neoproterozoic southern margin of the Avalon Plate consisting of leaky transform faults and trench segments characterized by magnetite serpentinite mantle wedge beneath forearcs. The Minas Fault/Collector Anomaly connects similar arc units in Cape Breton Island and southern New Brunswick, suggesting that they were already offset by the Minas transform fault in the late Neoproterozoic. Similar tectonic, palaeomagnetic and isotopic data in the Timan Orogen of Baltica suggest that Avalonia may correlate with the Kipchak arc.
Attenuation of Sialylation Augments Antitumor Immunity and Improves Response to Immunotherapy in Ovarian Cancer
Authors: Cao Kankan , Zhang Guodong , Yang Moran , Wang Yiying , He Mengdi , Zhang Chen , Huang Yan , Lu Jiaqi , Liu Haiou 
Published: May 2023

Abstract

Aberrant sialylation functions as an important modulator of all steps of malignant transformation. Therefore, targeting sialylation regulators, such as sialyltransferases and neuraminidases, is a potential strategy for treating cancer. Here, we found that elevated α2,3-sialyltransferase III (St3gal3) was associated with dismal prognosis in high-grade serous ovarian carcinoma (HGSC). St3gal3 knockdown antagonized subcutaneous tumor growth in immunocompetent, but not immunodeficient mice, with enhanced accumulation of functional CD8+ T cells and antitumor immune gene signatures. St3gal3 knockdown inhibited intraperitoneal tumor growth and repolarized tumor-associated macrophages from a protumorigenic M2-like to a tumor-suppressive M1-like phenotype. In vitro, St3gal3 knockdown tumor cells guided bone marrow–derived macrophages (BMDM) toward the M1-like phenotype under both direct contact and distant Transwell coculture conditions. Depletion of macrophages rescued the suppressed tumor growth induced by St3gal3 knockdown and completely suppressed infiltration of functional CD8+ T cells that rely on macrophage-derived CXCL10. St3gal3 engendered an immunosuppressive HGSC microenvironment characterized by an abundance of pro-tumorigenic macrophages and reduced cytotoxic T-cell infiltration. In vivo, St3gal3 knockdown improved effectiveness of dual immune checkpoint blockade (ICB) with αPD-1 and αCTLA4 antibodies. Preclinical inhibition of sialylation with ambroxol resulted in decreased tumor growth and prolonged the survival of tumor-bearing mice, which was enhanced by the addition of dual ICB. These findings indicate that altered sialylation induced by St3gal3 upregulation promotes a tumor-suppressive microenvironment in HGSC and targeting α2,3-sialylation may reprogram the immunosuppressive tumor microenvironment and improve the efficacy of immunotherapy.

Significance:
Blocking sialylation augments antitumor immunity and enhances response to immune checkpoint blockade therapy, highlighting a potential therapeutic approach for treating patients with high-grade serous ovarian cancer.
What Is Aristotle’s Metaphysics About?
Authors: Judson Lindsay 
Published: May 2023

Abstract
This paper argues that the discussion in which Aristotle engages in Metaphysics ΖΗ has the same starting-point as natural science: the principles of changing substances. These inquiries are nonetheless distinct because natural science uses these principles in its detailed investigations into natural substances, whereas ΖΗ reflect on the principles themselves. ΖΗ are an integral part of Aristotle’s inquiry into the principles of all substances, changing and unchanging: they are not merely preliminary to an inquiry into the latter kind. They are also an integral part of Aristotle’s ‘first philosophy’, alongside theology’s study of the nature and activity of unchanging substances.
‘Who Touched Me?’ Embodied Witness as Public Theology
Authors: Wivell Ruth 
Published: May 2023

Abstract
This article addresses how trauma might inform the way Mark’s account of the haemorrhaging woman is read, and what a Christology derived therefrom might offer to Christians who wish to witness to people’s traumatic and posttraumatic realities. If Christians and theologians are called to witness to others’ suffering and their attempts to make sense of it, then they need to be able to inhabit a space that draws forth stories of those disempowered and traumatized. In particular, this article explores these issues by addressing inter-related facets of Jesus the Christ in Mark 5:24–34 as he responds to the haemorrhaging woman and is involved in her healing. It is Jesus’s shift to witness – as he loses power and cognition – that brings about the hope of ongoing restoration of the woman’s body and spirit.
‘Flood this Nation with the Bible’: Rev. Godfridah Sumaili, Politics and the People’s Bible in Zambia
Authors: Kaunda Chammah J. 
Published: May 2023

Abstract
Ever since the Declaration of Zambia as a Christian nation in 1991, the Bible has become foundational in the public of life, and often cited in public debates. This article employs symbolic power as an analytical tool to examine Sumaili’s state theology of the Bible which politicized and reduced the Bible in the public into a state apparatus for defining, shaping, and determining the meaning and content for governing Zambia. It proposes a Pentecostal public theology of the people’s Bible as a site of struggle against politics of dehumanization, oppression, exploitation, and systematic inequalities.
Lost for Words: Samoa’s Constitutional Crisis and the Case for a Public Theology
Authors: Amosa Sam 
Published: May 2023

Abstract
The Samoan election of 2021 provoked a constitutional crisis. It brought to an end sixty years of political stability that had been determined by the interweaving of democratic ideals with indigenous cultural values and Christian principles. The election had led to a tie on the night and led to various legal appeals, protests and the reluctance of the Prime Minister of more than twenty years refusing to stand down. With one exception – the Roman Catholic Archbishop – the churches were silent, ‘lost for words’. The crisis happened at a time when the first wave of localized and contextual public theologies were beginning to appear in theological research. Their particular focus was on a range of other issues (mainly due to timing). Their emergence, nevertheless, invites a consideration of what such a public theology might look like in a society where there is no history of a prophetic voice and the cultural system of fa’aSamoa relies upon a principle of respect (which was violated during the crisis).
“Giving What They Hold Dear”: Safavid Diplomatic Gifts to Venice
Authors: Guliyev Ahmad 
Published: May 2023

Abstract
The exchange of gifts was an important aspect of the relations between the Safavid Empire and the Republic of Venice. Drawing on Venetian archival documents, the article aims to explore the nature and significance of Safavid diplomatic gift-giving to Venice in the first third of the seventeenth century. In particular, it examines the place and importance of precious objects in gift exchanges, looking at specific types of gifts given such as carpets, textiles, and weaponry. The article sheds light on the role religion played in the determination of a Shah’s choice of a gift to the Doge. Furthermore, this article examines how the diplomatic gifts from the Safavid rulers were viewed and conceived in Venice. Using a comparative perspective, the article explores the differences between the Safavid gift-giving strategies towards Venice and Ottomans. It reveals that the Safavids and Venetians had a common understanding of what was worthy of giving.
Science Counselors of the European Union – a Case Study of Science Diplomacy
Authors: Ruffini Pierre-Bruno 
Published: May 2023

Abstract
The posting of science attachés to diplomatic representations abroad is a tool particularly suited to the implementation of a science diplomacy strategy. The European Commission embarked on this practice by the end of the last century and today there are twelve science counselors stationed in European Union (EU) delegations. All of them were interviewed, and filled out a short survey, for this study. This article documents the particular profile and missions of the EU’s science counselors, to which no study has been devoted as such to date. The survey revealed their essential cross-cutting missions: promoting the research framework programs, and enhancing coordination with Member States’ science attachés. This article draws on interviewees’ statements and the existing literature in order to analyze and critically discuss the contribution of science counselors to the implementation of the EU’s science diplomacy and public diplomacy.
Tunisia’s Social Unrest: From July 2021 to Present
Authors: Mnasri Chamseddine 
Published: May 2023

Abstract
This paper is a critical examination of post-July 2021 Tunisia. It delves into four defining issues: first, the significant impact of President Kais Saied’s unexpected decision to suspend parliament and dismiss government on July 25, 2021; second, the various reactions to Saied’s move; third, the failed promises of Saied’s populist project in the face of an unprecedented political, economic, and social crisis; and fourth, drawing on resource mobilization theory, the paper will explain how the government’s policies have caused unprecedented social unrest, thereby sparking significant anti-government protests.
Conventionality Control and the Limits of Pro Persona Jurisprudence
Authors: Contesse Jorge 
Published: May 2023

Abstract
In Conventionality Control of Domestic Law: Constitutionalised International Adjudication and Internationalised Constitutional Adjudication, Yota Negishi advances a theory of conventionality control, a doctrine of interaction between international human rights law and national law, that puts at the center of such interaction the pro persona principle. This commentary analyses Negishi’s work, highlighting its major contributions and noting what it sees as problematic areas of the theory, in particular, the over reliance on the principle, and its use as a mechanism to allocate judicial competences. The commentary notes how the Inter-American Court of Human Rights’ use of the principle can explain some of its most expansive caselaw, a caselaw that has come under scrutiny by members of the Court and that deserves serious attention by legal scholars.
Conventionality Control Between International and Constitutional Law
Authors: Ragone Sabrina 
Published: May 2023

Abstract
This contribution addresses conventionality control in its double dimension, encompassing international law and constitutional law. It focuses on the comparative methodological issues when equating the Inter-American and the European systems of protection of human rights, taking into account the progressive “Europeanization” of the former’s case law. Then, it critically examines the question of judicial authority of domestic and international courts in multilevel systems, to raise a few points concerning the complex relationship between international courts and states.
Rejoinder from the Author
Authors: Negishi Yota 
Published: May 2023

Abstract
This rejoinder is to provide author’s answers to the questions posed by commentators. The first issues is the analytical scope and methods in comparison between the Inter-American and European Courts of Human Rights. The author particularly responds to the lack of analysis on social rights. The second issue is the political backlashes against the judicial control by human rights courts. The author replies that the role of “political”conventionality control complementing the judiciaries is of importance.
The Interplay of State Immunity and Contractual Forum Selection Clauses in Employment Cases: Return to Normalcy
Authors: Rossi Pierfrancesco 
Published: May 2023

Abstract
In Judgment No. 18801 of 2022, in the context of an employment dispute with a foreign State, the Corte di Cassazione declined to give effect to a contract clause conferring exclusive jurisdiction to the courts of the employer State and upheld Italian jurisdiction. With this decision, which was based on the limitations on party autonomy in respect to contracts of employment set forth in the EU Brussels I Regulation, the Court drastically departed from recent precedents where it had declined jurisdiction in the presence of similar contract clauses. Such precedents, in their turn, stood in stark contrast to the earlier jurisprudence of the Court, where jurisdiction had been affirmed based on the Brussels I Regulation. This contribution argues that this ruling constitutes a welcome and much-needed turnaround, bringing the Court’s case law back into line with EU law and the case law of the European Court of Justice and significantly improving the judicial protection afforded to employees of foreign States in Italy – a veritable return to normalcy in employment disputes with foreign States.
The nrrp as a “Self-Restraint” and as a Development of the (Spending) Conditionality Mechanism
Authors: Bartolucci Luca 
Published: May 2023

Abstract
The paper analyzes the conditionality mechanism triggered by the Next Generation EU and by the National Recovery and Resilience Plan. In particular, the interpretation used sees in the nrrp the last stage of the process of conditionality and as a development of the concept of external constraint. Finally, the nrrp is related to the monetary policies of the ecb and to the reform of European economic governance.
The Italian Right-Wing Government and the EU: an Interesting Case Study
Authors: Baraggia Antonia 
Published: May 2023

Abstract
The Italian general elections of September 2022 introduced several interesting novelties in Italian politics. Indeed, the election’s results – which marked the victory of a new governing coalition led by Brothers of Italy, a far-right party, together with the League, Forza Italia, and Noi Moderati – represent a turning point in Italian politics, a significant shift in the political spectrum. In this brief essay, I will tackle the implications of such a shift: after a quick overview of the constitutional guarantees of the Italian system, which, I argue, can protect Italian democracy from illiberal shifts, I will focus on one of the most interesting aspects of the new government, the attitude towards the EU and international law.