bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sociodemographic, occupational, and personal factors associated with sleep quality among Chinese medical staff: A web-based cross-sectional study
Authors: Tian Yusheng , Yue Yuchen , Yang Jiaxin , Chen Hui , Wang Jizhi , Liu Junyu , Ding Hui , Lu Lulu , Zhou Jiansong , Li Yamin 
Published: December 2022

BackgroundSleep quality among medical staff affects not only their own health but also the health of their patients. This study aimed to investigate the sociodemographic, occupational, and personal factors associated with sleep quality among medical staff in mainland China.MethodsAn online survey was conducted from January 10 to February 5, 2019, involving 3,684 medical staff (female: 84.9%; mean age: 31.6 ± 7.7; age range: 18–72). Sleep quality was measured by the Chinese version of the Pittsburgh Sleep Quality Index (C-PSQI). Sociodemographic, occupational characteristics, and personal lifestyle factors were measured by standard questions. Binary logistic regression analyses were used to determine the factors associated with sleep quality.Results57.9% (95% CI: 56.3–59.5%) of the study population experienced poor sleep quality (C-PSQI &gt; 5). Binary logistic regression showed that poor sleep quality were associated with lower level of education, higher level of hospital care, longer weekly working hours, more than 30 min of cell phone use at bedtime, shift work (OR 1.33, 95% CI[1.12–1.58], P = 0.001), lack of regular naps (OR 1.46, 95% CI[1.26–1.69], P &lt; 0.001) and lack of routine exercise (OR 1.69, 95% CI[1.46–1.97], P &lt; 0.001).ConclusionsPoor sleep quality is highly prevalent among medical staff in mainland China. The findings indicate that appropriate strategies, such as implementing regular breaks, regulating overtime work and vacation interruptions, as well as developing exercise programs, relaxation training, and stress-management programs could help improve the sleep quality of medical staff.
Evaluation of Zamia floridana A. DC. Leaves and Its Isolated Secondary Metabolites as Natural Anti-Toxoplasma and Anti-Cancer Agents Using In Vitro and In Silico Studies
Authors: El-Seadawy Hosam M. , Abo El-Seoud Kamilia A. , El-Aasr Mona , Tawfik Haytham O. , Eldehna Wagdy M. , Ragab Amany E. 
Published: December 2022

Toxoplasmosis and cancer are life-threatening diseases with worldwide distribution. However, currently used chemosynthetic treatments are not devoid of their own intrinsic problems. Natural metabolites are gaining attention due to their lower side effects. In this study, we investigated for the first time Zamia floridana leaves extract and its different fractions for their toxoplasmocidal activity, using Virulent RH Toxoplasma gondii, and cytotoxic activity against MCF-7 and HCT-116 cancer cell lines using MTT assay. The n-butanol fraction was the most potent fraction against T. gondii with an EC50 of 7.16 ± 0.4 µg/mL compared to cotrimoxazole (4.18 ± 0.3 µg/mL). In addition, the n-BuOH fraction showed a significant cytotoxicity against MCF-7 and HCT-116 with IC50 of 12.33 ± 1.1 and 17.88 ± 1.4 µg/mL, respectively, compared to doxorubicin (4.17 ± 0.2 and 5.23 ± 0.3 µg/mL, respectively), with higher safety index against normal cell line (WISH). Therefore, the n-BuOH fraction was investigated for its phytochemicals using extensive chromatographic techniques, which led to the isolation of six compounds that were fully characterized using different spectroscopic techniques. Three biflavonoids (1, 2 and 4) in addition to two phenolic acid derivatives (3 and 5) and a flavonoid glycoside (6) were isolated. Compounds (1, 3, 5 and 6) were reported for the first time from Z. floridana. In silico docking studies for toxoplasmocidal and cytotoxic effects of these compounds revealed that compounds (1, 2, 4 and 6) have promising inhibition potential of either thymidylate synthase-dihydrofolate reductase (TS-DHFR) or cyclin dependent kinase 2 (CDK2) target proteins. This study is considered the first report of chemical and biological investigation of Z. floridana leaves.
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation
Authors: Malek Rim , Simakov Alexey , Davis Audrey , Maj Maciej , Bernard Paul J. , Wnorowski Artur , Martin Helene , Marco-Contelles José , Chabchoub Fakher , Dallemagne Patrick , Rochais Christophe , Jozwiak Krzysztof , Ismaili Lhassane 
Published: December 2022

Novel multitarget-directed ligands BIGI 4a-d and BIGI 5a-d were designed and synthesized with a simple and cost-efficient procedure via a one-pot three-component Biginelli reaction targeting acetyl-/butyrylcholinesterases inhibition, calcium channel antagonism, and antioxidant ability. Among these multitarget-directed ligands, BIGI 4b, BIGI 4d, and BIGI 5b were identified as promising new hit compounds showing in vitro balanced activities toward the recognized AD targets. In addition, these compounds showed suitable physicochemical properties and a good druglikeness score predicted by Data Warrior software.
Medicalización de las desigualdades de género: una respuesta feministas desde la salud
Authors: Cardozo Virginia 
Published: December 2022

Este artículo apuesta a relatar la propuesta desarrollada en un barrio de Montevideo (Uruguay) entre los años 2016 y 2020 desde un servicio de salud. Se desarrolla un relato de experiencia que tiene como objetivo general reflexionar sobre la medicalización de las desigualdades de género en la atención a la salud de las mujeres. Los objetivos específicos son analizar el impacto del género como determinante social de la salud, describir situaciones frecuentes de medicalización de las desigualdades de género y compartir una experiencia alternativa desde la atención de salud para abordar el impacto de las desigualdades en salud sobre la salud de las mujeres. Como propuesta para trabajar los malestares de género que llevan a las consultas de salud se busca construir una respuesta que apueste a desestimular intervenciones patologizantes de los malestares de género y generar una estrategia terapéutica basada en el trabajo sobre el uso del espacio y el uso del tiempo. Esta experiencia es un camino de búsqueda de sanar entre mujeres, apostando a que el contacto con el equipo de atención en salud pueda generar una oportunidad para un proceso de empoderamiento a través de un tiempo/espacio desestimulando la medicalización de las desigualdades de género.
La Consejería en Sexualidades, Identidades de Género y situaciones de Violencia Patriarcal. Una experiencia de intervención feminista en el ámbito dela UNCuyo (2015-2021)
Authors: Serú Paulina , Anzorena Claudia 
Published: December 2022

El presente trabajo aborda una temática que ha adquirido gran relevancia en las acciones que vienen desarrollando los feminismos desde hace décadas: la visibilización de la desigualdad y la violencia de género y su problematización como un tema de agenda política ante el cual las comunicades universidades también son interpeladas para dar respuestas. En este sentido, abona desde su particularidad, el interés por un proceso reciente y potente, de ensanchamiento y profundización de las políticas de género en los ámbitos universitarios: un estudio de caso sobre la Consejería en Sexualidades, Identidades de Género y situaciones de Violencia Patriarcal creada en la Universidad Nacional de Cuyo, en 2015 como una experiencia de intervención feminista en el ámbito universitario.
El estudio realizado desde un diseño metodológico de tipo cualitativo, desde una perspectiva feministas, de la diversidad territorial y crítica de las organizaciones, se centra en el surgimiento del espacio, sus principales características y funciones. Explicamos el trabajo que realiza, la perspectiva desde la cual realiza sus intervenciones, y algunas tensiones y desafíos que la atraviesa en su objetivo de transversalizar la perspectiva de género en la UNCuyo.
Pengaruh Pemberian Pinjaman Modal Usaha Terhadap Peningkatan Pendapatan Pelaku Usaha (Studi Kasus Pada Usaha Perdagangan Di Desa Tameran)
Authors: Mahalizikri Irawan Fakhrudin , Herbi Herbi 
Published: December 2022

This research was carried out on tameran village trading business titled "Effect of Business Capital Lending on Increasing Income of Business Estimation"(Case Study on Trading Business in Tameran Village). In the preparation of this Thesis, the author only restricts to businesses that need funds or venture capital in 2018-2020. Capital borrowers aim to provide additional business capital in Tameran village. In this arrangement, to be able to find out the results of this study the author uses a quantitative methodology to determine the results between the two variables. Data collection was carried out by giving questionnaires totaling 76 respondents, which were distributed to business actors who borrowed funds. Based on the coefficient of determination test with the R Square value of SPSS Version 23, which is equal to 0.898, this figure is also called the coefficient of determination. The magnitude of the number 0.898 is the same as 89.8%. This means that 89.8% of the business capital variable affects the business income variable. While the rest (100% -89.8%), namely 10.2% of business capital, is influenced by other variables that are not included in this research model. Meanwhile, for T count> T Table, which is 25,527> 1.99, it means that H0 is rejected and Ha is accepted.
LITERATURE REVIEW: FACTORS ASSOCIATED WITH HYPERTENSION IN PREGNANCY
Authors: Astuti Eka Rati , Husain Fitry I , Sujawaty Sri 
Published: December 2022

AbstrakHipertensi adalah tekanan darah lebih dari 140/ 90 mmHg. Hipertensi merupakan salah satu masalah dunia yang melanda dunia. Sesuai informasi WHO (World Health Organization), hipertensi kehamilan adalah salah satu penyebab kesakitan dan kematian ibu dan bayi di seluruh dunia. Kebaruan dalam penelitian ini karena meneliti tentang Lierature Riview: Faktor – Faktor Yang Berhubungan Dengan Hipertensi Dalam Kehamilan. Tujuan dari penelitian ini yaitu untuk mengetahui faktor-faktor yang berhubungan dengan terjadinya hipertensi pada ibu hamil. Metode penelitian ini adalah literaturnya diambil dari 5 jurnal internasional bereputasi, 6 jurnal nasional terakreditasi sinta 4-6, dan 16 jurnal nasioanal ber-ISSN. Pada tahap pencarian jurnal diambil dari Elsevier dan Google Schoolar. Adapun artikel yang diambil dari tahun 2017-2022 dengan menggunakan kata kunci faktor AND hipertensi AND kehamilan. Hasil penelitian ini diambil dari beberapa jurnal menunjukkan bahwa faktor-faktor yang berhubungan dengan hipertensi dalam kehamilan yaitu umur (14 jurnal), riwayat hipertensi (11 jurnal), paritas (10 jurnal), obesitas (7 jurnal), stres (6 jurnal), merokok (4 jurnal), pedidikan, konsumsi makanan, dukungan keluarga (masing-masing 3 jurnal), serta aktivitas fisik dan genetik (masing-masing 2 jurnal). Kesimpulan dalam penelitian ini adalah faktor yang dominan yang berhubungan dengan hipertensi dalam kehamilan yaitu umur, riwayat hipertensi, paritas, obesitas, dan stres. Sedangkan yang paling dominan adalah faktor umur.Kata Kunci : Faktor – factor; Hipertensi; Kehamilan AbstractHypertension is blood pressure more than 140/90 mmHg. Hypertension is one of the world's problems that hit the world. According to WHO (World Health Organization) information, pregnancy hypertension is one of the leading causes of maternal and infant morbidity and mortality worldwide. The purpose of this study was to determine the factors associated with the occurrence of hypertension in pregnant women. This research method is taken from 5 reputable international journals, 6 national journals accredited by sinta 4-6, and 16 national journals with ISSN. In the search phase, the journals were taken from Elsevier and Google Schoolar. The articles were taken from 2017-2022 using the keywords AND factors of hypertension AND pregnancy. Results: the results of research from several journals show that the factors associated with hypertension in pregnancy are age (14 journals), history of hypertension (11 journals), parity (10 journals), obesity (7 journals), stress (6 journals), smoking (4 journals), education, food consumption, family support (3 journals each), and physical and genetic activity (2 journals each). Conclusions in the study the dominant factors associated with hypertension in pregnancy are age, history of hypertension, parity, obesity, and stress. While the most dominant is the age factor.Keywords: Factors; Hypertension; Pregnancy
Socio-legal conditionality of criminalization of socially dangerous acts committed in the securities market
Authors: Petryanina Olga , Kulikov Roman , Nazmeeva Leysan 
Published: December 2022

The development of the country’s economy and its integral element — the securities market, at all stages of the development of the state is under special attention from all subjects of economic activity. The criminal attractiveness of the economic sphere, the state’s promise to improve the economy and its versatile support raise the question of the content of the social and legal conditionality of the criminalization of socially dangerous acts committed in the securities market. The social and legal conditionality of socially dangerous activities is a very important criminal law and criminological institution. In the Russian Federation, given the unfriendly behavior on the part of foreign participants in the international securities market, it has its own characteristics. The fight against acts that encroach on the established procedure for the circulation of securities, which are deeply latent and entail serious economic losses for bona fide participants in the securities market, in a difficult economic situation, should be one of the priorities of modern criminal policy. The level of organization of these crimes is growing, as well as the increasing use of digital and virtual technologies in their commission.
Countering crimes committed in the securities market should be based on increasing the level of interaction between entities related to the activities of the securities market and the application of preventive organizational and legal and technical measures, including the criminal law format, based on the criteria for the social and legal conditionality of the criminalization of acts.
Problems of integrating digital and humanitarian technologies into the educational and training process of the University of the Ministry of Internal Affairs of Russia
Authors: Suprunov Aleksandr , Vasiliev Vyacheslav , Gorbachev Vladimir 
Published: December 2022

The modern educational process carried out in educational organizations on the territory of the Russian Federation is a continuous purposeful activity of authorized entities for the education and training of persons receiving education. Like any process that obviously involves the development and improvement of all subjects involved in it, continuous education is impossible without the constant integration of innovative technologies and techniques into it that determine its relevance and effectiveness. These include digital and humanitarian technologies that are being actively introduced into the educational and training activities of modern educational institutions of higher education of the Ministry of Internal Affairs of the Russian Federation.
The research is devoted to the analysis of the results of the introduction of digital and humanitarian technologies into the educational process of educational institutions of higher education, the identified problems and ways to solve them.
Empirical data on the use of modern means of stimulating the accused to voluntarily admit his guilt as of 2022
Authors: Ivanshina Anastasia 
Published: December 2022

The admission of guilt by the accused has always been relevant for the criminal process in Russia. For many years it occupied the position of the “queen of evidence” and had to be obtained by any means. The most common means of obtaining such a confession was torture. However, as a result of the criminal procedure reform, the accused’s confession of his guilt has become an ordinary, ordinary proof.
Despite the complete change in its status, it still remains necessary for the criminal process of Russia. In this regard, positive means of stimulating the accused have been developed for many years, which would not violate his rights and would not force such a confession. Currently, we have a whole set of effective and practical means of stimulating the accused to voluntarily admit his guilt. However, not all of them are relevant.
Thanks to the statistical indicators for 2021, as well as the survey conducted, the author identified the most popular means of encouraging the accused to voluntarily admit his guilt, as well as the least implemented in practice. In addition, this article reflects the dynamics of the implementation of incentive funds over the past five years, as well as conclusions for each of the funds presented.
The oretical aspects of the concept of legislative gaps
Authors: Gorbacheva Svetlana 
Published: December 2022

In modern Russia, the gaps in legal regulation can be called a permanent phenomenon, which is accompanied by the constant development of technologies and the emergence of new areas of social relations associated with it. It is also impossible not to recognize the transformation of many social relations, while their legal regulation has remained traditional. Undoubtedly, the coronovirus infection pandemic, which necessitated the implementation of legal regulation, had a serious impact on a number of areas. Definitely, this topic will never lose its relevance, since the scientific and legal literature recognizes the inevitability of the existence of gaps in law, due to the impossibility of creating a perfect law, with absolute completeness regulating all social relations subject to legal regulation, especially in conditions of constant development of objective reality.
In the study, from the point of view of theory, various positions of scientists on the issue of the relationship between the concepts of ˮgap in lawˮ and ˮgap in legislationˮ are analyzed, summarized and given; ˮdefect in lawˮ and ˮgap in lawˮ; ˮgap in the lawˮ and ˮgap in the lawˮ. The classification of gaps in law on various grounds is considered. The author pays special attention to the study of the causes of occurrence in law. In conclusion, the author emphasizes that in the legal doctrine there is no unified approach to the concept of a gap in law, a legislative gap or other categories that appear in the scientific and legal literature as synonymous.
On the issue of periodization of the formation of requirements and rules for the design of a normative legal text in Pre-Revolutionary Russia
Authors: Volk-Leonovich Stanislav , Orlov Dmitriy 
Published: December 2022

The problem of the design of the normative legal text is currently very relevant, since any deviations from the accepted standards form negative legal consequences, which can be difficult or impossible to overcome or eliminate at all. Thus, violation of the rules of registration, which are full of modern regulatory legal acts, entails a lot of negative legal phenomena, including: mistakes in law enforcement, destabilization of public relations, distortion of the original intention of the legislator, undermining the authority of the authorities and, as a consequence, legal nihilism. The rules and requirements for the design of a normative legal text need to be improved, and for this it is necessary to take into account all previously accumulated experience, identify and systematize it.
The scientific article is devoted to one of the little — studied and at the same time fundamental issue — the periodization of the formation of requirements and rules for the design of a normative legal text. The article defines the reasons and conditions for the formation of rules for the design of a normative legal text, analyzes the essential content features, identifies the stages of evolution of the formation of requirements and rules for the design of a normative legal text and gives their characteristics. The established periodization will make it possible to better understand the dependence of the design of the normative legal text on historical conditions, determine the features of Russian law-making and prepare recommendations for the legislator.
Peran Komunikasi Guru dalam Menumbuhkan Motivasi Belajar Siswa di Tingkat Sekolah Dasar/Madrasah Ibtidaiyah
Authors: Suparlan Suparlan 
Published: December 2022

ABSTRACT (ENGLISH)
Communication is the process of sending or receiving messages from one person to another, either directly or indirectly, in writing, orally or in non-verbal language. The person who communicates is called the communicator. People who are invited to communicate are called communicants. People who are able to communicate effectively are called communicative. A communicative person is a person who is able to convey information or messages to others, either directly or indirectly, in writing, verbally, or in non-verbal language so that other people can receive information (messages) in accordance with the expectations of the information provider (message). learning as a process of adaptation or adjustment of behavior that takes place progressively. Meanwhile, Morgan defines learning as a relatively permanent change in behavior as a result or result of a disturbing experience.
ABSTRAK (INDONESIA)
Komunikasi adalah proses penyampaian atau penerima pesan dari satu orang kepada orang lain, baik langsung maupun tidak langsung, secara tertulis, lisan maupun bahasa nonverbal. Orang yang melakukan komunikasi disebut komunikator. Orang yang diajak berkomunikasi disebut komunikan. Orang yang mampu berkomunikasi secara efektif disebut komunikatif. Orang yang komunikatif adalah orang yang mampu menyampaikan informasi atau pesan kepada orang lain, baik langsung maupun tidak langsung, secara tertulis, lisan, maupun bahasa nonverbal sehingga orang lain dapat menerima informasi (pesan) sesuai dengan harapan si pemberi informasi (pesan). belajar sebagai suatu proses adaptasi atau penyesuaian tingkah laku yang berlangsung secara progresif. Sedangkan Morgan mengartikan belajar sebagai suatu perubahan yang relatif menetap dalam tingkah laku sebagai akibat atau hasil dari pengalaman yang mengganggu
Implementasi Metode Ummi dalam Pembelajaran Al-Qur`An di MI As-Sunniyyah Lumajang
Authors: Syaikhu Ach 
Published: December 2022

ABSTRACT (ENGLISH)
The ummi method is a method that is carried out with individual classical models of teachers and students reading the Qur'an together. The purpose of this research is to find out how the ummi method is applied in improving the Al-Quran learning process for students. This study uses qualitative research and observation, interviews, and documentation as data collection techniques. The conclusion of this study shows that the implementation of the Ummi learning model is in a classical way, classical reading and listening, pure classical reading and listening.
ABSTRAK (INDONESIA)
Metode ummi adalah metode yang dilaksanakan dengan model klasikal individual guru dan siswa membaca Al-Qur`an bersama-sama. Adapun tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui bagaimana penerapan metode ummi dalam meningkatkan proses pembelajaran Al-Quran pada siswa. Penelitian ini menggunakan jenis penelitian kualitatif, tehnik pengumpulan data, observasi, interview, dan dokumentasi. Kesimpulan penelitian ini menujukkan bahwa implementasi model pembelajaran ummi yaitu dengan cara klasikal, klasikal baca simak, klasikal baca simak murni.