bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of delay in a Musca domestica houseflies model: Stability and Global Hopf Bifurcation
Authors: Zhang Xin , Shi Renxiang 
Published: March 2023

Abstract

The houseflies model with discrete delay is studied in both theoretical and numerical ways. The solution of the delayed system is positive and bounded. Choosing the delay as the bifurcation parameter, stability analysis for the positive equilibrium of the delayed model, local and global Hopf bifurcation are given in theoretical aspect. Dynamical behaviors such as supercritical Hopf bifurcation is detected by computer simulations. The theoretical analysis and numerical observations in this work are interesting in biomathematics research area.
Mathematics Subject Classification (2010). Primary 34C15, 34C23, 37G15, 37N25.
The Structural and Electrical properties of Guar Gum based
Authors: SRINI BOLLABATHINI , Sreek T. , Rajesh S. 
Published: March 2023

Abstract
Guar gum is an environmental tree-based natural polymer with a large molecular weight. Guar gum polymer electrolytes are new materials that are being developed for the applications of electrochemical devices such as supercapacitors, high energy density batteries, fuel cells, electrochromic displays, etc. The solution casting method has been employed to prepare solid-state composite Green-polymer electrolytes using Guar gum, Zinc Sulphate heptahydrate salt (ZnSO4.7H2O). These synthesized polymer electrolytes have been studied by using X-Ray Diffraction(XRD), Fourier Transformation Infrared (FTIR), Differential scanning calorimetry (DSC), Scanning Electron Microscope(SEM), and Electrical impedance Spectroscopy(ESI) techniques. The addition of the zinc (ZnSO4.7H2O) salt, to withstand the ion movement in composite guar gum matrix electrolyte was the main investigation in the present work. The complexation of polymer and salt was confirmed by the FTIR. The phase transition and amorphous nature were confirmed by X-Ray Diffraction (XRD). The glass transition temperature was calculated for all samples by using a DSC study. The scanning electron microscopy(SEM) technique investigated that the surface exhibited anisometric morphology (spherical and elongated)for pure guar gum and while in the composite polymer, bounded the salt ion within the guar gum matrix. The ionic conductivity was calculated using bulk resistance at room and different temperatures. The maximum ionic conductivity is 2.5x10-5 S/cm at 100oC for a pure guar gum sample, while with the addition of the salt guar gum, a non-linear variation of the conductivity was found. The long tail in dielectric constant(εʹ(ω)) and loss (εʺ(ω) analysis was refect the bulk capacitance nature of the sample. The non-Deby behavior and relaxation process was studied by dielectric modulus parameters.
The Prevalence and Severity of Anemia Among Malaria Patients With and Without Soil-Transmitted Helminths in Three Health Facilities of Arba Minch Town, Southern Ethiopia, a Comparative Cross-Sectional Study
Authors: Genanew Birhanu , Hailu Asrat 
Published: March 2023

Abstract
Background
Anemia is one of the severe clinical outcomes associated with concomitant infection of malaria and soil-transmitted helminths. It affects growth, physical fitness, and cognitive function, especially in children. The findings of previous studies done to assess the effect of malaria soil-transmitted helminths co-infection on anemia showed some variation. This indicates the need for further studies in different populations.
Method
An institutional-based cross-sectional study was conducted at three Governmental Health Institutions, Arba Minch, and southern Ethiopia from November 2020- February 2021 on a total of 321 malaria-positive study participants. Thick and thin blood films were prepared for microscopic examination of malaria parasites and identification of species. Malaria parasite count was done to determine the intensity of the infection. Stool wet mount was done to identify soil-transmitted helminths. Kato-Katz was done for microscopic quantitative examination of soil-transmitted helminths. Complete blood cell count was done to determine hemoglobin level and anemia prevalence. Socio-demographic data was collected using questionnaire. Data were analyzed using SPSS version 25. Independent samples t-test, one-way ANOVA, binary and multivariate logistic regression analyses were done.
Results
Anemia prevalence in this study was 38.3% and it was higher in the malaria with multiple soil-transmitted helminth co-infection groups (55.1%). Co-infection status (AOR = 3.591, CI: 1.468–8.788, P = 0.005), hookworm infection (AOR = 1.632, CI: 1.027–2.593, P = 0.038), and its intensity, A.lumbricoides infection (AOR = 2.095, CI: 1.286–3.411, P = 0.003), and its intensity were significant predictors of anemia in this study. Malaria parasite density was significantly higher in malaria with multiple STHs co-infected study participants F (2, 318) = 20.075. It increased with increasing intensity of hookworm, T.trichiura, and number of co-infecting helminth species. But it decreased with increasing intensity of A.lumbricoides and S.mansoni.
Conclusion
this finding suggests that co-infection of multiple soil-transmitted helminth and malaria are associated with anemia and low Hgb levels, this indicates the importance of integrated disease control interventions.
Initial Result of Heliocentric Distance Dependence of Zodiacal Light Observed by Hayabusa2#
Authors: Tsumura Kohji , Matsuura Shuji , Sano Kei , Iwata Takahiro , Takimoto Kohji , Yamada Manabu , Morota Tomokatsu , Kouyama Toru , Hayakawa Masahiko , Yokota Yasuhiro , Tatsumi Eri , Matsuoka Moe , Sakatani Naoya , Honda Rie , Kameda Shingo , Suzuki Hidehiko , Cho Yuichiro , Yoshioka Kazuo , Ogawa Kazunori , Shirai Kei , Sawada Hirotaka , Sugita Seiji 
Published: March 2023

Abstract
The zodiacal light (ZL) is sunlight scattered by interplanetary dust (IPD) in the optical wavelengths. The spatial distribution of IPD in the Solar system may hold an important key to understanding the evolution of the Solar system and material transportation within it. The IPD number density can be expressed as [[EQUATION]] , and the result of [[EQUATION]] was obtained by the previous observations from the interplanetary space by Helios 1/2 and Pioneer 10/11 in the 1970s and 1980s. However, no direct measurements of [[EQUATION]] based on the ZL observation from the interplanetary space outside the Earth's orbit have been conducted since then. Here we introduce the initial result of the ZL radial profile at optical wavelengths observed at 0.76-1.06 au by ONC-T with Hayabusa2# mission in 2021-2022. The obtained ZL brightness is well reproduced by the model brightness, but there is a small excess of the observed ZL brightness over the model brightness at around 0.9 au. The obtained radial power-law index is [[EQUATION]] , which is consistent with the previous results based on the ZL observations. The dominant uncertainty source arises from the uncertainty in the Diffuse Galactic Light estimation.
WITHDRAWN: Discrete-Time Noise-Suppression Neural Dynamics for Optical Remote Sensing Image Extraction
Authors: Xiong Yizhen , Wang Difeng , Fu Dongyang , Wang Yan 
Published: March 2023

Abstract
Remote sensing is a significant manner of observation at present, and how to extract the target object from optical remote sensing images quickly and accurately is a challenge. Accordingly, a discrete-time noise-suppression neural dynamics (DTNSND) model with an error-accumulation term is proposed to aid the constrained energy minimization scheme for extracting the target object, which restrains the effects of noises in the extraction process. Through theoretical analysis, it is proven that the DTNSND model excels at suppressing noise in diverse noisy environments. Furthermore, numerical simulations are provided to illustrate that the maximal steady-state residual error generated by the DTNSND model during the solution process is markedly lower than that generated by the comparative algorithms. Finally, extraction experiments, using an optical remote sensing image of the Arctic sea ice as an experimental material, confirm the feasibility of the DTNSND model in practice.
Surrogate Explanations for Role Discovery on Graphs
Authors: Cunningham Eoghan , Greene Derek 
Published: March 2023

Abstract
Role discovery is the task of dividing the set ofnodes on a graph into classes of structurally similar roles. Modern strategies for role discovery typically rely on graph embedding techniques, which are capable of recognising complex graph structures when reducing nodes to dense vector representations. However, when working with large, real-world networks, it is difficult to interpret or validate a set of roles identified according to these methods. In this work, motivated by advancements in the field of explainable artificial intelligence (XAI), we propose Surrogate Explanation for Role Discovery (SERD), a new framework for interpreting role assignments on large graphs using small subgraph structures known as graphlets. We demonstrate our framework on a small synthetic graph with prescribed structure, before applying them to a larger real-world network. In the second case, a large, multidisciplinary citation network, we successfully identify a number of important citation patterns or structures which reflect interdisciplinary research.
Reformulating Fick’s Law of Diffusion into a Half-Order Version, with Applications in the Physical Sciences
Authors: Myland Janice C. , Oldham Keith B. 
Published: March 2023

Abstract
Diffusion is ubiquitous in nature and underlies many of the processes studied by scientists. Fick’s second law, the partial differential equation that governs diffusion, lends itself to factoring, yielding simpler alternatives that incorporate semioperators. The semioperator approach aids experimentation in several scientific fields that feature diffusion. Illustrative applications to heat transport, chemical analysis, and electric circuitry are briefly reported.
AN EVALUATION ON TWO SAHABATKU INDONESIA COURSEBOOKS IN LITTLEJOHN’S TEXTBOOK ANALYSIS FRAMEWORK
Authors: Salsabilla Aulia 
Published: March 2023

The use of proper learning materials in foreign language learning have a pivotal role. Feasibility analysis on language learning material surely different from other subjects’. Sahabatku Indonesia coursebooks has been main reference for BIPA learning programs. This qualitative descriptive research evaluates Sahabatku Indonesia BIPA 3 and Sahabatku Indonesia untuk Pelajar BIPA 3 using Andrew Littlejohn's Textbook Analysis Framework in three steps of analysis. The result of the evaluation shows both coursebooks could accommodate in process of learning BIPA relatively effective. It appears from the linguistic aspect and cultural context in the coursebooks provided comprehensively. Nonetheless, the learning methods still can be improved to make more room for the learners to be more engaged in the language through more active roles in bringing or producing their related texts can still be improved.
Keywords: foreign language, learning materials, Indonesian language learning materials, evaluation.
HABs Karenia brevis and Pseudo-nitzschia pre- and post-Hurricane Michael
Authors: Alarcon Josh , Ward Lauren , Pan Ke , Gonsoroski Elaina , Uejio Christopher K. , Beitsch Leslie , Lichtveld Maureen Y. , Harville Emily W. , Sherchan Samendra 
Published: March 2023

Abstract
Increased occurrences of harmful algal blooms (HAB) in the Gulf of Mexico, and even worldwide, yield concern for increases in brevetoxin exposure leading to respiratory illness or even death, highlighting the need for extensive scientific research and human health monitoring. It is known that major events such as tropical storms and hurricanes are followed by periods of increased red tides caused by HABs; however, the nature by which phytoplankton blooms proliferate following major events remains a topic of great interest and research. The impact of Hurricane Michael on October 10, 2018 on HABs in the Florida panhandle was examined by analyzing data from the Florida Fish and Wildlife Conservation Commission in coordination with Normalized Fluorescence Line Height (nFLH) data from the University of South Florida College of Marine Science. Results presented here demonstrate four phases of HABs during storm events: 1. Pre-storm concentrations, 2. Decreased concentration during the storm, 3. Elevated concentrations following the storm and 4. Recovery period. This time frame can serve to be important in understanding the health dynamics of coastal systems following major storm events.
Evaluation of water quality in the upper and lower catchments of the Kelani River Basin, Sri Lanka
Authors: Narangoda Chandima , Amarathunga Deeptha , Dangalle Chandima Deepani 
Published: March 2023

AbstractKelani River is the principal consumable water source for 80% of the population in the Colombo district and an important ecosystem complex for the freshwater fish biota of Sri Lanka. However, it is the most polluted river in the country. The present study was conducted to determine the water quality parameters and pollution of the upper and lower catchments of the river and select the most suitable parameters for predicting the pollution of each catchment. Thirteen locations of each catchment were selected for the study, and 14 water quality parameters were recorded by standard techniques. Measurements were compared with the standard values permissible for drinking purposes and aquatic life and subjected to principal component analysis. The study revealed that the most polluted catchment of the Kelani River was the lower catchment, and the chemical oxygen demand (COD) and water pH were selected as the most suitable parameters to predict the pollution levels of the lower catchment. The nitrate concentration and COD were selected as the most suitable water quality parameters to predict the pollution of the upper catchment. The present study indicates an accelerating trend in water pollution of the Kelani River when compared with studies conducted two decades ago.
Effect of APOE4 Allele and Gender on the Rate of Atrophy in the Hippocampus,
Entorhinal Cortex, and Fusiform Gyrus in Alzheimer’s Disease
Authors: Hamza Eid Abo , Moustafa Ahmed A. , Tindle Richard , Karki Rasu , Nalla Shahed , Hamid Mohamed S. , EL HAJ Mohamad 
Published: March 2023

Background:
The hippocampus, entorhinal cortex, and fusiform gyrus are brain areas that deteriorate during early-stage Alzheimer’s disease (AD). The ApoE4 allele has been identified as a risk factor for AD development, is linked to an increase in the aggregation of amyloid ß (Aß) plaques in the brain, and is responsible for atrophy of the hippocampal area. However, to our knowledge, the rate of deterioration over time in individuals with AD, with or without the ApoE4 allele, has not been investigated.

Method:
In this study, we, for the first time, analyze atrophy in these brain structures in AD patients with and without the ApoE4 using the Alzheimer’s Disease Neuroimaging Initiative (ADNI) dataset.

Results:
It was found that the rate of decrease in the volume of these brain areas over 12 months was related to the presence of ApoE4. Further, we found that neural atrophy was not different for female and male patients, unlike prior studies, suggesting that the presence of ApoE4 is not linked to the gender difference in AD.

Conclusion:
Our results confirm and extend previous findings, showing that the ApoE4 allele gradually impacts brain regions impacted by AD.

other:
N/A
Therapeutic Potential of Metformin-preconditioned Mesenchymal Stem
Cells for Pancreatic Regeneration
Authors: Kamble Prajakta , Desai Shivani , Bhonde Ramesh , Sanap Avinash , Shimpi Jagruti , Kumbhar Rohit , Kokani Manesh , Kharat Avinash 
Published: March 2023

Background:
Diabetes occurs due to insulin deficiency or less insulin. To manage this condition,
insulin administration as well as increased insulin sensitivity is required, but exogeneous insulin
cannot replace the sensitive and gentle regulation of blood glucose levels same as β cells of healthy
individuals. By considering the ability of regeneration and differentiation of stem cells, the current
study planned to evaluate the effect of metformin preconditioned buccal fat pad (BFP) derived mesenchymal
stem cells (MSCs) on streptozotocin (STZ) induced diabetes mellitus in Wistar rats.

Materials & Methods:
The disease condition was established by using a diabetes-inducing agent STZ
in Wistar rats. Then, the animals were grouped into disease control, blank, and test groups. Only the
test group received the metformin-preconditioned cells. The total study period for this experiment was
33 days. During this period, the animals were monitored for blood glucose level, body weight, and
food-water intake twice a week. At the end of 33 days, the biochemical estimations for serum insulin
level and pancreatic insulin level were performed. Also, histopathology of the pancreas, liver and
skeletal muscle was performed.

Results:
The test groups showed a decline in the blood glucose level and an increase in the serum pancreatic
insulin level as compared to the disease group. No significant change in food and water intake
was observed within the three groups, while body weight was significantly reduced in the test group
when compared with the blank group, but the life span was increased when compared with the disease
group.

Conclusion:
In the present study, we concluded that metformin preconditioned buccal fat pad-derived
mesenchymal stem cells have the ability to regenerate damaged pancreatic β cells and have antidiabetic
activity, and this therapy is a better choice for future research.
Buddleoside Inhibits Progression of Liver Cancer by Regulating NFκB
Signaling Pathway
Authors: Zhang Li , Sun Lizhi , Gao Shuchun , Yang Weihua , Zhuang Yuanmei , Xu Mingjie 
Published: March 2023

Background:
Liver cancer is a severe incurable disease and causes several thousands of deaths
each year. Flavonoids are a class of bioactive compounds possessing anti-cancer activity.

Objective:
The objective of this study is to investigate the role of Buddleoside, one type of flavonoids, in
carcinogenesis of liver cancer.

Methods:
Cell proliferation was detected by CCK-8 method, while cell invasion was by transwell assay,
cell apoptosis by Annexin V/FITC-A staining. Western blotting technology was used to explore the
mechanism of Buddleoside in liver cancer.

Results:
It was demonstrated that buddleoside inhibited cell proliferation in a dose-dependent manner and
suppressed cell invasion in liver cancer. The inhibition rates of buddleoside in the invasion of both Huh-7
and Hep3B cells were above 75%. The apoptotic rates in the two cell lines were increased by about 10
folds in buddleoside group. Then, the expression levels of NFκB/p65 and IKK were decreased when IκB
increased in buddleoside-treated Huh-7 cells, suggesting the inhibition of NFκB signaling pathway.
Moreover, the expression levels of cleaved caspase-3 and Bax were upregulated while HSDL2 decreased
in buddleoside group. In contrast, after NFκB/p65 was overexpressed, the expression patterns of these
molecules were reversed partially. Consistently, the abilities of cell proliferation and cell invasion were
recovered, while cell apoptosis decreased after NFκB/p65 overexpression.

Conclusion:
Buddleoside inhibits proliferation, and invasion and induces apoptosis in liver cancer by
regulating NFκB signaling pathway. This study provides us with new proofs for the possible application
of buddleoside in liver cancer therapy.
12 Cases of Haglund’s Syndrome Detected through MRI
Authors: Zhang Kun , Zhou Shuwei , Luo Wuxing , Wang Siyu 
Published: March 2023

Background:
Haglund’s syndrome is a common cause of heel pain but often neglected clinically. Haglund’s syndrome refers to a series of symptoms caused by impingement among posterosuperior prominence of the calcaneus, bursa and Achilles tendon. It is difficult to distinguish Haglund’s syndrome from other causes of heel pain by clinical diagnosis. Imageology is of great value in the diagnosis of Haglund’s syndrome.

Objective:
Our study aims to summarize the Magnet resonance (MR) imaging characteristics of Haglund’s syndrome and provide some reference to clinical work.

Method:
We retrospectively analyzed the MR images of 11 patients (6 males; 5 females; 6 right ankles, 4 left ankles, 1 bimalleolar ankles) who have been clinically and radiologically confirmed Haglund’s syndrome. Observation contents: morphological changes of calcaneus and talus, abnormal signal of calcaneus, abnormal Achilles tendon, and soft tissue abnormalities around Achilles tendon. Combined with literature reviews, summarize the MR imaging features of Haglund’s syndrome.

Results:
In 12 ankles, all ankles showed posterosuperior prominence of the calcaneus and Achilles tendon degeneration; 7 ankles showed bone marrow edema; 6 Achilles tendons were graded as either type II or type III tendinosis; 5 Achilles tendons showed partial tear; 12 ankles showed retrocalcaneal bursitis, 7 ankles showed retro-Achilles bursitis, 6 ankles showed Kager’s fat pad edema.

Conclusion:
This study found that MR images of Haglund's syndrome showed bone edema of the calcaneus, degeneration and partial tear of the Achilles tendon, the retrocalcaneal and retro-Achilles bursas, and Kager’s fat pad edema.
Eco-friendly Synthesis and Characterization of Silver Nanoparticles using Juglans
regia Extract and their Anti-Trichomonas vaginalis, Anticancer, and Antimicrobial
Effects
Authors: Şimşek Ahmet , Küçük Burak , Aydın Ali , Aydın Davut , Karadağ Ahmet 
Published: March 2023

Background:
Green synthesis is an efficient and eco-friendly method that has been used frequently in silver
nanoparticle production in recent years. This method facilitates the production of nanoparticles using various organisms,
such as plants, and is also cheaper and easier to apply than the other techniques.

Aims:
This study aims to find possible mechanisms and pharmacological effects of cubic silver nanoparticles (AgNPs).

Objectives:
This study characterizes cubic AgNPs and describes in detail their anticancer, antimicrobial, and anti-
Trichomonas vaginalis abilities.

Methods:
Silver nanoparticles were produced by green synthesis using Juglans regia (walnut) leaf aqueous extract. We
validated the formation of AgNPs by UV-vis spectroscopy, FTIR analysis, and SEM micrographs. To determine the
pharmacological effects of the AgNPs, we conducted anti-cancer, anti-bacterial, and anti-parasitic activity experiments.

Results:
Cytotoxicity data revealed that AgNPs have cellular inhibitory properties on cancerous MCF7 (breast), HeLa
(cervix), C6 (glioma), and HT29 (colorectal) cell lines. Similar results are also obtained with anti-bacterial and anti-
Trichomonas vaginalis activity experiments. At certain concentrations, AgNPs displayed stronger anti-bacterial activities
than the sulbactam/cefoperazone antibiotic combination in five bacteria species. Furthermore, the 12-h AgNPs
treatment exhibited satisfactory anti-Trichomonas vaginalis activity similar to the FDA-approved metronidazole.

conclusion:
Consequently, AgNPs produced by the green synthesis method by Juglans regia leaves showed remarkable
anti-carcinogenic, anti-bacterial, and anti-trichomonas vaginalis activities. We propose the potential usefulness of
green synthesized AgNPs as therapeutics.