bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing correlated big data privacy using differential privacy and machine learning
Authors: Biswas Sreemoyee , Fole Anuja , Khare Nilay , Agrawal Pragati 
Published: April 2023

AbstractData are often correlated in real-world datasets. Existing data privacy algorithms did not consider data correlation an inherent property of datasets. This data correlation caused privacy leakages that most researchers left unnoticed. Such privacy leakages are often caused by homogeneity, background knowledge, and linkage attacks, and the probability of such attacks increases with the magnitude of correlation among data. This problem further got magnified by the large size of real-world datasets, and we refer to these large datasets as ’Big Data.’ Several researchers proposed algorithms using machine learning models, correlation analysis, and data privacy algorithms to prevent privacy leakages due to correlation in large-sized data. The current proposed work first analyses the correlation among data. We studied the Mutual Information Correlation analysis technique and the distance correlation analysis technique for data correlation analysis. We found out distance correlation analysis technique to be more accurate for high-dimensional data. It then divides the data into blocks using the correlation computed earlier and applies the differential privacy algorithm to ensure the data privacy expectations. The results are derived based upon multiple parameters such as data utility, mean average error, variation with data size, and privacy budget values. The results showed that the proposed methodology provides better data utility when compared to the works of other researchers. Also, the data privacy commitments offered by the proposed method are comparable to the other results. Thus, the proposed methodology gives a better data utility while maintaining the required data privacy commitments.
Continuous monitoring of instrumental clock errors at 50 volcanoes in Japan based on seismic interferometry
Authors: Hirose Takashi , Ueda Hideki 
Published: April 2023

AbstractThe correct absolute time of a seismogram is an important prerequisite for many seismological processing methods. Recently, seismic interferometry has been applied to continuously estimate instrumental clock errors in certain regions. However, previous studies have focused on estimating clock errors in only one target region for each study, and data processing methods that provide more stable results in different regions have not been explored. This study presents a new method to estimate clock errors that are more stable in various regions based on seismic interferometry with windowed cross-correlation and least absolute deviation regression. The applicability of this method was validated by its application to 50 active volcanoes in Japan. We found clock errors at 23 stations at 13 volcanoes between January 2017 and December 2021. The maximum amplitude of the clock errors ranged between 0.24 and 18.27 s. This value range is significantly larger than the amplitude of the background fluctuation in the estimated values of clock errors, which is less than 0.05 s for most volcanoes. A comparison of different approaches for the estimation of clock error shows that our proposed method that uses windowed cross-correlation and least absolute deviation regression can reduce the effect of waveform changes in seismic ambient noise cross-correlation functions, probably because of noise source fluctuations. Managing the time stamps of data using the method proposed in this study will contribute to data quality assurance and ensure the reliability of analysis using time information in various study regions.
Graphical Abstract
Susceptibility of typical marine geological disasters: an overview
Authors: Liu Xiaolei , Wang Yueying , Zhang Hong , Guo Xingsen 
Published: April 2023

Abstract
Background
Marine geological disasters (i.e., catastrophic events occurring in marine environments) may seriously threaten the safety of engineering facilities, life, and property in shallow- and deep-sea areas. The development of marine resources and energy and the protection of the marine geo-environment are topics of intense interest globally, and these activities inevitably require the assessment of marine geological disasters, which are receiving increasing attention from academic and industrial communities. However, as a prospective analysis for the risk assessment and management of marine geological disasters, the susceptibility of marine geological disasters, referring to a qualitative or quantitative description of the type, volume (or area), and spatial distribution of existing or potential geological disasters, is still in the exploration stage.

Results
In this study, we systematically combine the theoretical basis and methods for the analysis of the susceptibility of marine geological disasters (i.e., heuristic approach, deterministic approach, and statistical approach). Taking two widely studied marine geological disasters (i.e., seabed liquefaction and submarine landslides) as examples, we review their triggering mechanism, condition factors, methodological advances, and susceptibility maps. Subsequently, some challenges in the susceptibility assessment of the marine geological disasters associated with seabed liquefaction and submarine landslides and extension to other types of marine geological disasters are briefly summarized and discussed, involving an incomplete evaluation system, poor applicability of methods, and insufficient databases.

Conclusion
Based on a literature review using the extensive literature database, we focused on the susceptibility of two typical marine geological disasters (i.e., seabed liquefaction and submarine landslides) and systematically summarized the development history, methods, results, problems, and future directions. According to the challenges of this field, we recommend that relevant organizations focus on the construction of a susceptibility system and study the triggering mechanisms of marine geological disasters. Long-term in situ observation efforts should also be supported to obtain more data to improve the disaster inventory. Ultimately, more reliable methods can help improve the credibility and usefulness of susceptibility analysis results.
Long-term response to pimitespib in postoperative recurrent gastrointestinal stromal tumors with PDGFRA D842V mutation: a case report
Authors: Teranishi Ryugo , Takahashi Tsuyoshi , Kurokawa Yukinori , Saito Takuro , Yamamoto Kazuyoshi , Yamashita Kotaro , Tanaka Koji , Makino Tomoki , Nakajima Kiyokazu , Eguchi Hidetoshi , Doki Yuichiro 
Published: April 2023

Abstract
Background
Exon 18 D842V, which is a point mutation from aspartic acid to valine at codon 842, is the most frequent mutation in Platelet-Derived Growth Factor Receptor alpha (PDGFRA)-mutated gastrointestinal stromal tumor (GIST). In the Japanese GIST guidelines, no standard systematic therapy is available for this type of GIST, which is refractory after recurrence. Recently, pimitespib (PIMI), a novel heat shock protein 90 (HSP90) inhibitor, was approved for the treatment of advanced GIST in a phase III study. This report presents a case of a long-term response to PIMI in GIST with PDGFRA D842V mutation.

Case presentation
A 55-year-old woman was diagnosed with primary GIST of the stomach and underwent partial gastrectomy. Eight years after the operation, recurrent GISTs were identified as multiple recurrent peritoneal GISTs in the upper right abdomen and pelvic cavity. We administered tyrosine kinase inhibitors, but they achieved poor effects. After failure of the standard treatment, PIMI was administered and achieved a partial response in the patient. The highest reduction rate was 32.7%. After PIMI failed, we performed multiplex gene panel testing, which revealed the PDGFRA D842V mutation.

Conclusions
We report the first case of long-term response to PIMI in PDGFRA D842V mutant GIST. Pimitespib may be effective for treating GIST harboring this mutation by inhibiting HSP90.
Context-specific variation and repeatability in behavioral traits of bent-wing bats
Authors: Kuo Yu-Jen , Lee Ya-Fu , Kuo Yen-Min , Tai Yik Ling 
Published: April 2023

AbstractAnimals may show consistent among-individual behavioral differences over time and in different contexts, and these tendencies may be correlated to one another and emerge as behavioral syndromes. The cross-context variation in these behavioral tendencies, however, is rarely explored with animals in contexts associated with different locomotion modes. This study assessed the variation and repeatability in behavioral traits of bent-wing batsMiniopterus fuliginosusin southern Taiwan, and the effects of contextual settings associated with locomotion mode. The bats were sampled in the dry winter season, and their behaviors were measured in hole-board box (HB) and tunnel box (TB) tests, both suited for quadrupedal movements of the bats, and flight-tent (FT) tests that allowed for flying behaviors. The bats in the FT tests showed more interindividual and between-trial behavioral variation than those in the HB and TB tests. Nearly all of the behaviors in the TB and FT tests, but only half of those in the HB tests, showed medium to high repeatability. These repeatable behaviors were grouped into distinct behavioral traits of boldness, activity, and exploration, which were correlated to one another across contexts. In addition, we observed a consistently higher correlation between behavioral categories across the HB and TB contexts than between either of these contexts and the FT context. The results indicate consistent among-individual behavioral differences across time and contexts in wildly caught bent-wing bats. The findings of behavioral repeatability and cross-context correlations also indicate context-dependent variation and suggest that test devices which allow for flight behaviors, such as flight tents or cages, may provide a more suitable setting for measuring the behaviors and animal personalities of bats, particularly for those species that display less or little quadrupedal movements.
Correlation between hyperreflective foci and visual function testing in eyes with intermediate age-related macular degeneration
Authors: Liu T. Y. Alvin , Wang Jiangxia , Csaky Karl G. 
Published: April 2023

Abstract
Background
To investigate the relationship between intraretinal hyperreflective foci (HRF) and visual function in intermediate age-related macular degeneration (iAMD).

Methods
Retrospective, cross-sectional study. iAMD patients underwent spectral domain optical coherence tomography (SD-OCT) imaging and vision function testing: normal luminance best corrected visual acuity (VA), low luminance VA (LLVA), quantitative contrast sensitivity function (qCSF), low luminance qCSF (LLqCSF), and mesopic microperimetry. Each OCT volume was graded for the presence and number of HRF. Each HRF was graded for: separation from the retinal pigment epithelium (RPE), above drusen, and shadowing. Central drusen volume was calculated by the built-in functionality of the commercial OCT software after manual segmentation of the RPE and Bruch’s membrane.

Results
HRF group: 11 eyes; 9 patients; mean age 75.7 years. No-HRF group: 11 eyes; 10 patients; mean age 74.8 years. In linear mixed effect model adjusting for cube-root transformed drusen volume, HRF group showed statistically significant worse VA, LLVA, LLqCSF, and microperimetry. HRF group showed worse cone function, as measured by our pre-defined multicomponent endpoint, incorporating LLVA, LLqCSF and microperimetry (p = 0.018). For eyes with HRF, # of HRF did not correlate with any functional measures; however, % of HRF separated from RPE and # of HRF that created shadowing were statistically associated with low luminance deficit (LLD).

Conclusions
The association between the presence of HRF and worse cone visual function supports the hypothesis that eyes with HRF have more advanced disease.
New neighborhood, old habits? Delivery preferences of residents in new development areas and their assessment of alternative parcel logistics concepts: a case study of Berlin
Authors: Gruber Johannes , Heldt Benjamin , Seidel Saskia 
Published: April 2023

AbstractVarious alternative solutions for sustainable last-mile parcel deliveries have been piloted and partially put into operation in Europe in the past decade. However, these delivery concepts have mainly been considered in inner-city areas. There are a few examples of the application of these concepts in peripheral urban areas, where new housing is being built to accommodate high population pressure. However, it is unclear whether the delivery preferences of residents in new neighbourhoods differ from those of the population average. This research conducted a case study in the western outskirts of Berlin, examining two newly built neighbourhoods and one existing residential area. Results from three survey waves of residents (N = 645) show that conventional doorstep delivery is preferred by 80% of the respondents. Nonetheless, there is a high willingness to use alternative delivery options, and respondents see benefits in climate-friendly delivery methods. This research also examines the willingness to pay for alternative parcel logistics concepts, which seems to be too low at the moment (at around €1 per shipment) to compensate for the additional costs of an operational change. However, the results also show an increasing awareness of and preferences for new delivery concepts, thus providing practical implications for planners and logistics operators alike.
Multivariate roles of litter traits on moisture and flammability of temperate northeastern North American tree species
Authors: Kreye Jesse K. , Kane Jeffrey M. , Varner J. Morgan 
Published: April 2023

AbstractBackgroundTree litter is the primary fuel affecting surface fire behavior in most fire-prone forest and woodland ecosystems in northeastern North America. Fire exclusion and land use changes have dramatically altered fire regimes in many of these ecosystems, shifting toward species that reinforce the continued diminution of fire. Comparative litter flammability studies provide a useful approach to identify the corresponding leaf and litter bed traits that drive the positive feedback termed “mesophication” in these ecosystems.ResultsIn this study, we measured laboratory flammability and moisture characteristics of leaf litter from 17 common tree species in temperate forests of northeastern North America. Principal components analysis of flammability and moisture data resulted in species separating along a pyrophyte-to-mesophyte gradient. PyrophyticQuercuslitter was the most flammable of all species, andPinuslitter dried the most rapidly and flamed for the longest duration. The remaining mesophytic species grouped into either a high moisture retention-poor burning cluster (Acer rubrum,Betula alleghaniensis,Nyssa sylvatica,Carya glabra,C. tomentosa) or an intermediate flammability cluster (Acer saccharum,C. ovata,Tilia americana). Several litter traits were associated with multivariate factors. Leaf length, density, curling, surface area-to-volume, and litter bed bulk density were associated with the factor comprising saturation moisture content, flaming time, and consumption. Specific leaf area was related to moisture time-lag and flame height. Litter bed packing ratio was most related to smoldering duration.ConclusionsInterspecific variability in leaf and litter bed traits explained substantial differences in moisture dynamics and flammability among the species examined. These findings extend our understanding of litter traits’ influence on the combustion environment and affirm the potential effects of pyrophytic and mesophytic tree species on contemporary fire regimes in northeastern North American forests.
A case report of anti-NMDA receptor encephalitis in a young Egyptian female patient presenting with hyperreligiosity
Authors: Ibrahim Hamdi , Ali Attaa , Maksod Safwat Abdel , Khorshed Magdy , Wassef Mona , Alfishawy Mostafa , Rady Hanan , Mohamed Adel , Mahmod Mohamed , Ismael Khaled , Haron Marwa , Said Suzan , Adel Riham , Mohamed Noha 
Published: April 2023

AbstractAnti-n-methyl-d-aspartate receptor (NMDAR) encephalitis is a form of autoimmune encephalitis that remains under-recognized due to the variability of the initial symptoms and can be misdiagnosed as viral encephalitis or other pathogens. This syndrome has been predominantly described in young females including personality changes, autonomic dysfunctions, and neurologic decompensation.About half of the cases have tumors, most commonly teratomas of the ovaries; another established trigger is herpes viral encephalitis, while the cause in other cases is unclear. In case of clinical suspicion, electroencephalogram and brain magnetic resonance imaging are useful, but lumbar puncture for cerebrospinal fluid analysis is used to confirm the diagnosis. Treatment for this disease includes immunosuppression, plasmapheresis, and tumor resection when indicated. In this case report, we present a case that presented with hyperreligiosity and proved to have autoimmune encephalitis.The main purpose of our case is to increase awareness regarding immune-mediated encephalitis, especially the anti-NMDAR encephalitis.
Evaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma
Authors: Youssef Gilbert , Rahman Rifaquat , Bay Camden , Wang Wei , Lim-Fat Mary Jane , Arnaout Omar , Bi Wenya Linda , Cagney Daniel N. , Chang Yuh-Shin , Cloughesy Timothy F. , DeSalvo Matthew , Ellingson Benjamin M. , Flood Thomas F. , Gerstner Elizabeth R. , Gonzalez Castro L. Nicolas , Guenette Jeffrey P. , Kim Albert E. , Lee Eudocia Q. , McFaline-Figueroa Jose R. , Potter Christopher A. , Reardon David A. , Huang Raymond Y. , Wen Patrick Y. 
Published: April 2023

PURPOSE The Response Assessment in Neuro-Oncology (RANO) criteria are widely used in high-grade glioma clinical trials. We compared the RANO criteria with updated modifications (modified RANO [mRANO] and immunotherapy RANO [iRANO] criteria) in patients with newly diagnosed glioblastoma (nGBM) and recurrent GBM (rGBM) to evaluate the performance of each set of criteria and inform the development of the planned RANO 2.0 update. MATERIALS AND METHODS Evaluation of tumor measurements and fluid-attenuated inversion recovery (FLAIR) sequences were performed by blinded readers to determine disease progression using RANO, mRANO, iRANO, and other response assessment criteria. Spearman's correlations between progression-free survival (PFS) and overall survival (OS) were calculated. RESULTS Five hundred twenty-six nGBM and 580 rGBM cases were included. Spearman's correlations were similar between RANO and mRANO (0.69 [95% CI, 0.62 to 0.75] v 0.67 [95% CI, 0.60 to 0.73]) in nGBM and rGBM (0.48 [95% CI, 0.40 to 0.55] v 0.50 [95% CI, 0.42 to 0.57]). In nGBM, requirement of a confirmation scan within 12 weeks of completion of radiotherapy to determine progression was associated with improved correlations. Use of the postradiation magnetic resonance imaging (MRI) as baseline scan was associated with improved correlation compared with use of the pre-radiation MRI (0.67 [95% CI, 0.60 to 0.73] v 0.53 [95% CI, 0.42 to 0.62]). Evaluation of FLAIR sequences did not improve the correlation. Among patients who received immunotherapy, Spearman's correlations were similar among RANO, mRANO, and iRANO. CONCLUSION RANO and mRANO demonstrated similar correlations between PFS and OS. Confirmation scans were only beneficial in nGBM within 12 weeks of completion of radiotherapy, and there was a trend in favor of the use of postradiation MRI as the baseline scan in nGBM. Evaluation of FLAIR can be omitted. The iRANO criteria did not add significant benefit in patients who received immune checkpoint inhibitors.
On the doubly anharmonic oscillator in an elastic environment in the presence of a point-like defect
Authors: Vitória R. L. L. , Anderson T. da Silva Kleber 
Published: April 2023

Abstract
We have investigated a doubly anharmonic oscillator in an elastic medium characterized by the presence of a point-like defect, where we obtain analytically your solution of bound states. We show that it is not possible to obtain a unique expression for the energy profile of the quantum system, but rather an expression corresponding to each radial mode of the system. Furthermore, an interesting quantum effect is presented: the three parameters that characterize the doubly anharmonic oscillator are quantized, that is, they depend on the quantum numbers of the system.
Integrating biomechanics in evolutionary studies, with examples from the amphidromous goby model system
Authors: Blob Richard W. , Diamond Kelly M. , Lagarde Raphaël , Maie Takashi , Moody Kristine N. , Palecek Amanda M. , Ward Jessica L. , Schoenfuss Heiko L. 
Published: April 2023

ABSTRACTThe functional capacities of animals are a primary factor determining survival in nature. In this context, understanding the biomechanical performance of animals can provide insight into diverse aspects of their biology, ranging from ecological distributions across habitat gradients to the evolutionary diversification of lineages. To survive and reproduce in the face of environmental pressures, animals must perform a wide range of tasks, some of which entail tradeoffs between competing demands. Moreover, the demands encountered by animals can change through ontogeny as they grow, sexually mature or migrate across environmental gradients. To understand how mechanisms that underlie functional performance contribute to survival and diversification across challenging and variable habitats, we have pursued diverse studies of the comparative biomechanics of amphidromous goby fishes across functional requirements ranging from prey capture and fast-start swimming to adhesion and waterfall climbing. The pan-tropical distribution of these fishes has provided opportunities for repeated testing of evolutionary hypotheses. By synthesizing data from the lab and field, across approaches spanning high-speed kinematics, selection trials, suction pressure recordings, mechanical property testing, muscle fiber-type measurements and physical modeling of bioinspired designs, we have clarified how multiple axes of variation in biomechanical performance associate with the ecological and evolutionary diversity of these fishes. Our studies of how these fishes meet both common and extreme functional demands add new, complementary perspectives to frameworks developed from other systems, and illustrate how integrating knowledge of the mechanical underpinnings of diverse aspects of performance can give critical insights into ecological and evolutionary questions.