bluuebunny/crossref_metadata_2025_split huggingface dataset:
PROLONGED STORAGE OF THAWED RED BLOOD CELLS
Authors: Orlyk Volodymyr , Kondratskyi Bohdan , Vynarchyk Mariya , Prymak Sofia , Savuliak Halyna , Novak Vasyl 
Published: December 2022

Introduction. In modern transfusion practice, both in peacetime and in military conditions, red blood cells (RBCs) are widely used as the main component of donor blood. Cryopreserved red blood cells are considered the most safe and high-quality RBC-containing environment. However, the storage period of thawed RBCs after cryopreservation is limited to 24 hours, and significantly complicates their use. Therefore, extending the storage period of thawed RBCs is relevant for the blood service. Research objective: study the RBCs morphological state and functional completeness that were cryopreserved at -40ºС and stored for 7 days at a temperature of +2ºС - +4ºС after thawing.
Materials and methods. The object of the study were RBCs that were cryopreserved at -40ºС and stored for 7 days at a temperature of +2ºС - +4ºС after thawing. Deglycerolization of the thawed red blood cells, cryopreserved at -40ºС, required three time washing by using reverse cytoagglomeration. Thawed RBCs were re-suspended in lactate-sucrose-phosphate solution. After RBC thawing and storage for 7 days (186 doses) in the suspension the following indicators were studied: free hemoglobin, extracellular potassium, adenosine triphosphoric acid (ATP), 2,3-diphosphoglycerate (2,3-DPG), hematocrit, degree of hemoglobin affinity to oxygen (P50,), viscosity coefficient, osmotic stability, electrophoretic mobility of erythrocytes. as well as the total number of cells lost and recovered.
Results. After storage for 7 days of suspension of thawed RBCs at a temperature of +2ºС - +4ºС indicators of free hemoglobin (0,62±0,02 g/l), extracellular potassium (2,7±0,3 mmol/l), hematocrit (0,4±0,02 l/l) were within normal limits. Osmotic resistance (0,46±0,02%), electrophoretic mobility (0,94±0,04 µm·cm·V-1·s-1) of RBCs, suspension viscosity factor (5,5±0,20mPa·С) did not exhibit changes in comparison with normal values. High levels of ATP indicators (3,0±0,2 µmol/gHb) and 2,3-DPG (10,5±1,3 µmol/gHb) were established. Indicator Р50 (24,1±1,3 hPa) corresponded to low hemoglobine affinity for oxygen. After 7-day storage at +2ºС - +4ºС total cell loss was insignificant and amounted to 5,6±0,4%. High percentage of viable thawed RBCs 94,4±0,5% was shown.
Conclusions. Deglycerolization of thawed red blood cells, cryopreserved at -40ºС, by reverse cytoagglomeration, as well as use of lactate-sucrose-phosphate solution for washed RBCs resuspending promote prolongation of thawed RBCs storage period up to 7 days at +2ºС - +4ºС in viable condition.
PENGARUH DIAMETER BLADE TIPE LURUS TERHADAP EFISIENSI TURBIN VORTEKS MENGGUNAKAN METODE CFD
Authors: Andriyan Ari , Permatasari Rosyida 
Published: December 2022

Salah satu sistem yang digunakan oleh Pembangkit Listrik Tenaga Mikro Hidro adalah mikro hidro vorteks. Mikro hidro vorteks menggunakan energi kinetik air yang membentuk pusaran yang akan menggerakkan blade turbin. Faktor yang dapat ditinjau agar mendapatkan efisiensi turbin yang optimal adalah jenis ukuran pada blade. Tujuan penelitian ini adalah untuk mengetahui pengaruh diameter blade tipe lurus terhadap efisiensi turbin menggunakan metoda CFD. Tipe blade yang digunakan adalah tipe lurus dengan diameter 20cm, 25cm, dan 30cm. Performa turbin didapat menggunakan metode Computational Fluid Dynamics (CFD) dengan simulasi software ANSYS Fluent. Hasil simulasi yang diperoleh adalah nilai performa tertinggi dari turbin vorteks terjadi pada uji parameter blade ukuran 30cm dengan nilai daya 775Watt, nilai putaran turbin 847rpm, nilai kecepatan sudut () pada 88,7rad/s, nilai torsi pada 8,51J, dan nilai efisiensi mencapai angka 73%.

ABSTRACT
One of the systems used by the Micro Hydro Power Plant is the micro hydro vortex. Micro hydro vortex uses the kinetic energy of water to form a vortex that will drive the turbine blades. Factors that can be reviewed in order to obtain optimal turbine efficiency is the type of blade size. The purpose of this study was to determine the effect of straight type blade diameter on turbine efficiency using the CFD method. The type of blade used is a straight type with a diameter of 20cm, 25cm, and 30cm. Turbine performance is obtained using the Computational Fluid Dynamics (CFD) method with ANSYS Fluent software simulation. The simulation results obtained are the highest performance value of the vortex turbine occurs in the 30cm blade parameter test with a power value of 775Watt, turbine rotation value 847rpm, angular velocity () value at 88.7rad/s, torque value at 8.51J, and efficiency reaches 73%.
PENGGUNAAN SKOR KANDIDA UNTUK PEMBERIAN ANTIJAMUR RASIONAL PASA PASIEN ICU DENGAN RISIKO CANDIDIASIS INVASIF
Authors: Bella Isa , Hartanti Monica Dwi , Prasetyaningsih Noviani , Amalia Husnun 
Published: December 2022

Pasien yang dirawat di ICU memiliki risiko tinggi terserang kandidiasis invasive. Hal ini dikarenakan kondisi klinis dan tatalaksana pada pasien ICU yang menjadi faktor risiko terjadinya infeksi invasif oleh candida. Hal yang dapat menyebabkan adalah penggunaan antibiotik spektrum luas dalam jangka waktu lama, penyakit penyerta yang mengakibatkan kondisi imunokompromais, riwayat operasi abdomen, pemakaian obat-obat imunosupresan, pemberian nutrisi total parenteral, dan pemakaian alat-alat invasif antara lain central venous catheter (CVC) dan ventilator. Pemberian anti jamur empirik pada pasien sakit kritis dengan kolonisasi Candida sp. atau pasien dengan faktor risiko lainnya merupakan intervensi dini yang diperlukan. Pemberian antijamur sedini mungkin pada pasien sakit kritis terduga kandidiasis invasif di ICU dapat menurunkan angka kematian. Pada keadaan normal Candida dapat berkolonisasi di saluran cerna, saluran napas bagian atas, vagina dan kulit. Sehingga isolat Candida sp. yang didapat dari biakan sampel sputum, broncho-alveolar lavage (BAL), brush protected specimen (BPS), dan sekret endotrakeal, belum dapat disimpulkan sebagai etiologi penyebab infeksi, masih terdapat kemungkinan merupakan komensal. Klinisi membutuhkan tersedianya pedoman pemberian antijamur empirik untuk pasien ICU guna mencapai hasil klinis yang diharapkan dan menghindari penggunaan antijamur yang berlebihan. Skor kandida dari Leon menawarkan penggunaan yang mudah untuk membantu klinisi menggolongkan pasien sakit kritis ICU yang perlu mendapat terapi empirik anti jamur dan pasien yang kecil sekali kemungkinan menderita kandidiasis invasif. Peningkatan spesifisitas pemberian antijamur empirik untuk pasien yang memiliki risiko menderita kandidiasis invasif dapat mengurangi biaya pengobatan yang tidak diperlukan dan mengurangi laju timbulnya resistensi terhadap obat antijamur.
Pengembangan Metode Pembelajaran Nilai Agama dan Moral di Era New Normal: Studi Kasus pada Pendidikan Anak Usia Dini
Authors: Indah Daratista  , Jaenullah Jaenullah  
Published: December 2022

Pandemi covid-19 membuat semua jenis aktivitas dilakukan dari rumah sebagai upaya meminimalisir penyebaran virusnya. Dalam pelaksanaannya, pendidikan Agama Islam pada tingkat pendidikan anak usia dini yang dikenal dengan istilah Nilai Agama dan Moral, terdapat berbagai tantangan dalam proses pengembangan metode pembelajaran yang dilakukan pada masa new normal. Sehingga dengan adanya penelitian ini, pembelajaran nilai agama dan moral dapat dikembangkan pada berbagai metode pembelajaran. Penelitian ini menggunakan jenis penelitian kualitatif studi kasus, dengan menggunakan teknik purposive sampling. Sumber data primer yang didapat dari hasil wawancara kepada kepala sekolah dan pendidik yang merupakan alumni pendidikan agama islam. Teknik analisis data yang digunakan dalam penelitian ini adalah teknik analisis reduksi data, penyajian data serta penarikan kesimpulan. Hasil penelitian mengatakan bahwa meskipun proses pembelajaran dilakukan secara daring, namun metodologi pembelajaran tetap digunakan oleh pendidik. Dengan menyesuaikan bahan pembelajaran serta situasi dan kondisi peserta didik di rumah, sehingga pendidik, peserta didik dan orang tua dapat melakukan proses pembelajaran untuk mencapai tujuan pembelajaran nilai agama dan moral
Comparison of Huffman Algorithm and Lempel Ziv Welch Algorithm in Text File Compression
Authors: Fauzan Mohamad Nurkamal , Alif Muhammad , Prianto3 Cahyo 
Published: December 2022

The development of data storage hardware is very rapidly over time. In line with the development of storage hardware, the amount of digital data shared on the internet is increasing every day. That way no matter how big the size of the storage device we have, of course, it will only be a matter of time until that storage space is exhausted. Therefore, in terms of maximizing storage space, a technique called compression emerged. This study focuses on a comparative analysis of 2 Lossless compression technique algorithms, namely the Huffman algorithm and Lempel Ziv Welch (LZW). A number of test files with different file types are applied to both algorithms that are compared. The performance of the algorithm is determined based on the comparison of space saving and compression time. The test results showed that the Lempel Ziv Welch (LZW) algorithm was superior to Huffman’s algorithm in .txt file type compression and .csv, the average space savings produced were 63.85% and 77.56%. The degree of compression speed that each algorithm produces is directly proportional to the file size.
أثر سلوك مواطنة الزبون في تعزيز القدرات التسويقية دراسة تحليلية لآراء المديرين في عدد من المؤسسات الصحية الخاصة في محافظة دهوك
Authors: Ihsan.ali Ihsan.hussein 
Published: December 2022

(الملخص)
إن الغرض من البحث هو معرفة الأثر الذي يؤديه سلوك مواطنة الزبون في تعزيز القدرات التسويقية، ونظراً لأهمية القطاع الصحي في حياة الفرد فقد أُجريت الدراسة في عدد من المؤسسات الصحية الخاصة في محافظة دهوك، كما افترض البحث الى وجود علاقة ارتباط وتأثير ذات دلالات احصائية بين متغيري سلوك مواطنة الزبون والقدرات التسويقية في المؤسسات الصحية المبحوثة . وتم استخدام استمارة الاستبيانة ، كوسيلة لجمع البيانات ، والتي وزعت على عدد من المؤسسات الصحية المبحوثة ، حيث تم توزيع (50) استمارة وتم استرجاع (45) استمارة صالحة للتحليل . ولتحليـل البيانات تم استخدام برنامج SPSS Version 22 والذي من خلاله تم الحصـول علـى التكرارات والنسب المئوية , والأوساط الحسابية والانحراف المعياري وذلك لاستخدامها في وصف وتحليل متغيرات البحث وتشخيصها ، وتم استخدام اختبار معامل الارتباط البسيط لتحديد قوة وطبيعة العلاقة بين متغيرات البحث ، والانحدار الخطي البسيط ، لقياس معنوية تأثير المتغير المستقل سلوك مواطنة الزبون في المتغير المعتمد القدرات التسويقية.
وتوصل البحث الى عدد من الاستنتاجات أهمها تبين بأن القدرات التسويقية يصعب على المنافسين تقليدها لارتباطها بتاريخ المؤسسة وثقافتها وخبرتها وتجاربها وبالتالي فإنها ستحقق ميزة تنافسية مستدامة للمؤسسة واختتم البحث بعدد من القترحات أهمها التركيز على كسب الزبائن الذين يدافعون عن المؤسسة من خلال سماع صوتهم ومناقشة آرائهم ومقترحاتهم حول الخدمات المقدمة وكيفية تطويرها. التي من الممكن ان تعزز أو تدعم الجوانب الإيجابية للميدان المبحوث وتعالج السلبيات إذا أُخذت بذلك مستقبلاً.
What is the right to food?
Authors: Kent George 
Published: December 2022

On October 28, 2022 Michael Fakhri, the United Nations Special Rapporteur on the Right to Food presented a report to the United Nations General Assembly, the highest level of governance in the world (Fakhri, Michael 2022). He called on the United Nations system to strengthen its efforts to ensure fulfillment of the right to food. These Special Rapporteurs have led the efforts for many years. In 2005 I published a book titled Freedom From Want: The Human Right to Adequate food. (Kent 2005). Its preface was written by Jean Zeigler, the first United Nations Special Rapporteur on the Right to Food, starting in 2000. He summarized my book, with a conclusion that in effect introduces this commentary: “Human rights are not only unashamedly utopian, but also eminently practical. Human rights can make a difference. It is time to make the right to food a reality.” This commentary discusses how the goal of making the right to food a reality could be expedited by developing a clear and widely shared understanding of what it means.
Students’ Perception toward English Online Presentation on Instagram
Authors: Mazulfah Mazulzah , Suriyah Eni 
Published: December 2022

This study has purpose to know students' perception of English online presentations on Instagram, its advantages and its disadvantages that are seen from students' point of view. A qualitative method was employed in this article. Observation, documentation, and interview are used to collect the data. There are ten students involved in the discussion. The result shows that students positively perceive English online presentations on Instagram. With presentation via Instagram, there are several advantages, including (1) it is neater; (2) no need to open other applications; (3) more concise; (4) easy to use; (5) all presentations and comments are stored securely. However, there are still some drawbacks to using Instagram for presentation, namely (1) not being able to contain all the material and explanations; (2) cannot use audio and video for presentation; (3) requiring a lot of internet quota and a sound signal; (4) students do not focus because they are distracted by other entertainment on Instagram; (5) too many questions; (6) access to Instagram is only owned by lecturers; (7) the audience takes a long time in responding; (8) confusing for some students who have this experience for the first time.
Oküler Dominans ve Lateralite ile Akomodasyon Arasındaki İlişkinin Değerlendirilmesi
Authors: YILDIZ Merve Beyza , ÖZTÜRK Yücel , BOLAÇ Rüveyde , YILDIZ Sevcan , YILDIZ Elvin 
Published: December 2022

Amaç: Monovizyon presbiyopik tedavi uygulamalarında oküler dominansın klinik önemi artmıştır.
Dominant ve dominant olmayan gözde akomodatif fonksiyonu araştıran az sayıda çalışmada çelişkili
sonuçlar bildirilmiştir. Çalışmamızda oküler dominans ve lateralitenin akomodasyon üzerindeki etkisini
değerlendirmek amaçlanmıştır.
Gereç ve Yöntemler: Çalışmaya otuz beş sağlıklı, genç izometropik katılımcı dahil edildi. Oküler
dominans, kart içinde delik testi kullanılarak belirlendi. Monoküler görüş koşulları altında Hartmann-
Shack aberometresi kullanılarak, 0,5 diyoptrilik artışlarla 0,5 ila 5 diyoptri arasında artan akomodatif
uyarana verilen akomodatif yanıtlar ölçüldü.
Bulgular: Katılımcıların yaş ortalaması 31,49 ± 4,22 (24-38) idi. Yirmi ikisi (%62,9) kadın, 13’ü (%37,1)
erkekti. Yirmi yedi (%77,1) olguda sağ göz, 8 olguda (%22,9) sol göz dominant idi. Dominant ve
dominant olmayan gözler arasında kırma kusuru (sferik, silindirik ve sferik eşdeğer) açısından anlamlı
bir fark yoktu (p>0,05). Dominant ve dominant olmayan gözler arasında 0,5 ila 5 diyoptrilik akomodatif
uyarana verilen akomodatif yanıtlarda anlamlı fark yoktu (p>0,05). Ayrıca, sağ ve sol gözlerin akomodatif
yanıtları benzerdi (p>0,05).
Sonuç: Çalışmamızda sağlıklı genç izometropik katılımcıların dominant ve dominant olmayan gözlerinin
farklı akomodatif uyaranlara akomodatif yanıtları benzer bulundu. Sağ ve sol göz arasında da
fark yoktu. Akomodasyonda oküler dominans ve lateralitenin rolünü anlamak için daha fazla çalışmaya
ihtiyaç vardır.
F-18 FDG ile PET/BT Görüntüleme Yapılan Hastaların Taburculuğu Sırasında Çevresel Radyasyon Güvenliği
Authors: USLU ERDEMİR Rabiye , SALİHOĞLU Yavuz Sami 
Published: December 2022

Amaç: Pozitron-emisyon-tomografisi/ bilgisayarlı tomografi (PET/BT) bir nükleer tıp görüntüleme yöntemidir‎ ve yaygın olarak onkolojide kullanılır. PET/BT görüntüleme yönteminde kullanılan F(flor)-18 radyoizotopu konvansiyonel nükleer tıpta kullanılan diğer radyoizotoplara göre daha yüksek foton enerjisine sahiptir. Çalışmamızda F-18 fluorodeoksiglukoz (FDG) ile PET/BT çekimi yapılan hastaların taburculuk sırasında çevreye salınan radyasyonun doz hızının ölçülmesi ve çevresel radyasyon maruziyetinin değerlendirilmesi amaçlanmıştır.
Yöntem: Çalışmamıza, Zonguldak Bülent Ecevit Üniversitesi Nükleer Tıp PET/BT ünitesine başvuran toplam 353 (E/K=177/176) hasta dahil edilmiştir. Hastalara F-18 FDG ile PET/BT çekimi yapıldıktan sonra taburcu edilmeden önce 0.5 metre (m), 1 m ve 2 m mesafeden toraks düzeyinden Geiger-Müller probu kullanılarak doz hızı ölçümleri yapılmış ve kayıt altına alınmıştır. Ölçümler arasında istatistiksel olarak anlamlı farklılık olup olmadığı değerlendirilmiştir.
Bulgular: Hastalara IV yol ile 331±149 megabecquerel (MBq) (Aralık: 182-481) radyoaktif madde enjekte edilmiş ve PET/BT ünitesinde enjeksiyon sonrası 104,5±34,5 dk (Aralık: 70 -139) beklemiştir. Taburculuk sırasında 0,5 m, 1 m ve 2 m m mesafelerden alınan radyasyon doz hızı ölçümleri, sırasıyla 33,20±20,50 mikrosievert/saat (µSv/sa), 15,94±10,55 µSv/sa ve 6,56 ±4,43 µSv/sa olarak hesaplanmıştır.
Sonuç: F-18 FDG PET/ BT çekimi sonrası taburculuk sırasında hastaların 0.5,1 ve 2 m mesafelerdeki doz hızı ölçümlerinin, uluslararası ve ulusal radyasyon düzenleme kuralları göz önünde bulundurulduğunda, çevresel radyasyon güvenliği açısından bir tehlike arz etmediği gösterilmiştir. F-18 FDG enjeksiyonundan yaklaşık iki saat sonra hastayla temas edenler için ciddi radyasyon riski bulunmamakta olup güvenli bir şekilde taburcu edilebilmektedir.
Identification of Novel Mutations in Children with Hereditary Spherocytosis by Targeted Exome Sequencing: A Single Center Experience
Authors: KOCAAĞA Ayça , ÇAKMAK Hatice Mine 
Published: December 2022

Aim: Hereditary spherocytosis (HS) is a prevalent cause of congenital hemolytic anemia in Northern
Europeans. It is characterized by spherocytes resulting from defects in the erythrocyte structural
membrane proteins spectrin and ankyrin. To date, more than five candidate genes, including ANK1,
SPTB, SPTA1, SLC4A1, and EPB42 have been linked to HS. Here, we aim to investigate the presence
of novel as well as known mutations in eight Turkish children with clinically suspected HS.
Material and Methods: We presented the clinical features of the patients and identified the causative
gene variants using targeted exome sequencing. Eight children who were clinically suspected of having
HS enrolled in this study. A family and medical history, clinical examination, relevant laboratory test
results, osmotic fragility test (OFT), and genetic results were evaluated.
Results: Six causative variants, including three ANK1 variants, two SPTB variants and one SLC4A1
variant were detected. All these mutations were novel variants. ANK1 and SPTB are the most common
mutant genes in children with HS.
Conclusion: This study expanded the mutation spectrum of ANK1, SPTB and SLC4A1. This is the first
study to determine the genetic and clinical characteristics of children with HS in Turkey.
The Effect of Project Based Learning Integrated STEM to Increase Science Process Skill
Authors: Lumbantobing Septina Severina , Faradiba Faradiba , Prabowo Diaz Jubairy , Sianturi Manogari , Guswantoro Taat 
Published: December 2022

This research aims to determine the effect of project-based learning integrated with the STEM method on the greenhouse effect and global warming on science process skills of class XI of the MIPA program in Senior High School in 9 Jakarta. This research is experimental research with two groups. Class control using discovery learning and class experiment using PJBL integrated with STEM. The instrument is a multiple-choice test with as many as 20 questions that use science process skills indicators. Analysis of this research data using the independent sample t-test was used to see the effect of the learning model on the science process skills, and the results obtained showed a significant effect. From the results of the analysis data, there is an effect of PjBL learning integrated STEM method to increase science process skills of students of class XI. Applying project-based learning integrated with STEM dramatically improves students' abilities, especially in observing, applying and conducting experiments. For the questionnaire students' responses to the implementation of the learning model, more than 80% of students were becoming more motivated in learning, more help understanding the subject matter, and could improve their problem-solving abilities.
Range of Motion (ROM) Aktif Kaki Meningkatkan Sensitivitas Kaki pada Penderita Diabetes Melitus
Authors: Putriyani Nila , Mulyaningsih Mulyaningsih , Hartutik Sri 
Published: December 2022

Latar Belakang: Penderita diabetes mellitus semakin meningkat dari tahun ke tahun. Penderita diabetes mellitus dapat mengalami berbagai macam komplikasi yang dapat mengakibatkan menurunnya fungsi tubuh, salah satunya yaitu penurunan sentitivitas kaki. Data menunjukkan bahwa 1 dari 5 orang diabetes melitus mengalami penurunan sensitivitas kaki. Berbagai upaya dapat dilakukan untuk mengatasi masalah tersebut, salah satunya yaitu Range of Motion (ROM) aktif kaki. ROM aktif kaki merupakan gerakan dasar untuk meningkatkan sensitivitas kaki pada penderita diabetes mellitus. Tujuan: Mengetahui pengaruh ROM aktif kaki terhadap tingkat sensitivitas kaki pada penderita diabetes mellitus. Metode Penelitian: Penelitian ini merupakan penelitian Pre-Eksperimental tanpa kelompok kontrol dengan rancangan One Grup Pretest-Postest. Teknik pengambilan sampling menggunakan purposive sampling dengan jumlah responden 20 orang. Hasil: Sebelum dilakukan tindakan mayoritas responden memiliki tingkat sensitifitas sedang (70%). Setelah dilakukan ROM aktif, terdapat 40% dari responden yang mempunyai tingkat sensitivitas kaki baik. Hasil analisis menunjukkan ada pengaruh ROM aktif kaki terhadap tingkat senisitivitas kaki pada penderita diabetes mellitus. Kesimpulan: Range Of Motion (ROM) aktif kaki dapat meningkatkan senisitivitas kaki pada penderita diabetes mellitus.
Pengaruh Terapi Guided Imagery terhadap Perubahan Tekanan Darah pada Penderita Hipertensi di Wilayah Puskesmas Jayengan Surakarta
Authors: Aji Prima Trisna , Rizkasari Elinda , Pujiyanto Pujiyanto 
Published: December 2022

Latar Belakang: Penyakit Hipertensi merupakan salah satu penyakit yang menduduki peringkat kedua pada pasien rawat jalan diunit layanan kesehatan. Hipertensi juga merupakan penyakit “The Sillent Killer” dimana penyakit ini tidak ada keluhan tetapi penyakit ini bisa menyebabkan kematian yang mendadak. Penatalaksanaan penyakit hipertensi antara lain dengan penatalaksanaan farmakologis dan non farmakologis. Salah satu tindakan non farmakologis adalah tindakan terapi quided imagery. Di wilayah Puskesmas Penumping Surakarta peringkat tertinggi adalah penyakit hipertensi dimana penyakit ini banyak diderita oleh lansia. Tujuan: Penelitian ini bertujuan untuk mengetahui pengaruh terapi quided imagery terhadap perubahan tekanan darah pada hipertensi di wilayah Puskesmas Jayengan Surakarta. Metode: Desain penelitian pra eksperimental menggunakan one group pretest-postest design. Jumlah sampel sebanyak 40 penderita hipertensi. Dengan tekhnik purposive sampling. Desain penelitian pra eksperimental menggunakan metode one group pretest-posttest design. Jumlah sampel sebanyak 29 responden dengan teknik purposive sampling. Untuk uji beda menggunakan Wilcoxon Signed Rank test. Hasil: Hasil uji statistik nilai p value tekanan darah sistole sebelum dan sesudah dilakukan terapi Guided Imagery (0,001) lebih kecil dari nilai alpha (0,05). Kesimpulan: Kesimpulan dari penelitian ini adalah ada pengaruh terapi quided imagery terhadap perubahan tekanan darah pada pasien Hipertensi diwilayah Puskesmas Jayengan Surakarta.