bluuebunny/crossref_metadata_2025_split huggingface dataset:
Targeted recruitment and the role of choice in the engagement of youth in a randomised smartphone-based mental health study in India, South Africa, and the UK: results from the MindKind Study
Authors: Sieberts Solveig K. , Burn Anne-Marie , Carey Emma Grace , Carlson Sonia , Fernandes Blossom , Kalha Jasmine , Lindani Simthembile , Marten Carly , Neelakantan Lakshmi , Ranganathan Swetha , Sams Nichole , Scanlan Erin Joy , Shah Himani , Sumant Sushmita , Suver Christine , Tummalacherla Meghasyam , Velloza Jennifer ,   The MindKind Consortium, Areán Patricia A. , Collins Pamela Y. , Fazel Mina , Ford Tamsin , Freeman Melvyn , Pathare Soumitra , Zingela Zukiswa , Doerr Megan 
Published: August 2023

Background: The global ubiquity of smartphone use among young people makes them excellent candidates for collecting data about individuals’ lived experiences and their relationships to mental health. However, to-date most app-based studies have been conducted in North America and Europe. Understanding young people’s willingness to participate in app-based research and share information about their mental health is key to understanding the feasibility of broad-scale research using these approaches. We aimed to understand the recruitment and engagement approaches influencing young peoples’ (aged 16-24) participation in app-based studies of mental health. We hypothesised that providing a choice of study topics will improve engagement. Methods: We developed a 12-week pilot study of mental health implemented in the MindKind app, designed to assess participants’ willingness to engage in remote mental health research, both actively and passively. Enrollees were randomised to one of two different engagement arms, either selecting their study topics of interest or receiving a fixed assignment of study topics, in order to understand the role of choice in study engagement. This pilot study was conducted in India, South Africa, and the United Kingdom. Different recruitment strategies were employed in each location. Results: The MindKind Study recruited 1,034 (India), 932 (South Africa) and 1,609 (UK) participants. Engagement differed by country with median days of activity = 2, 6, and 11 for India, South Africa, and UK, respectively. Most surprisingly, participants given a choice of study topics showed lower engagement relative to participants assigned to fixed topics (Hazard Ratio = 0.82). Conclusions: We observe equal or better engagement compared to previous comparable app-based studies of mental health. While providing participants a choice of study topics showed no advantage in our study, our qualitative analysis of participant feedback provides additional suggestions for improving engagement in future studies.
Cytotoxicity Activity of Crude Extract Produced by Marine Isolate (MS19) from Sea Water collected from Bay of Bengal, India
Authors: P Lalitha , P Gayathri , K A Paari 
Published: August 2023

Marine microbes comprises approximately a half of the total global biodiversity. Sea offers an enormous resource for novel bioactive compounds and it has been classified as the largest remaining reservoir of natural molecules to be evaluated for drug activity. Marine bacteria have been received attention of researchers due to their innate potential to produce diverse compounds that attracts biological properties such as anticancer, anti-inflammatory, antimicrobial and antioxidant properties. In this study, we reported isolation of 10 strains from sea water and tested them with standard biochemical test and their potential to utilize carbon sugar, to confirm the Actinomycetes character. Among the isolates 10 and 1 was recorded to be gram positive. Carbon utilization test revealed that all the isolates utilized dextrose and none of the isolates utilized ducitol. Strain MS19 a non-motile, catalase positive, oxidase positive, and round shape strain was isolated from sea water of the Bay of Bengal.
Work Ethics and Value System - a Fact Finding Study of Corporate Practices
Authors: James Leena , Shelvi Uma 
Published: August 2023

The concept of work ethics and value system is a strategic factor which shapes how efficiently the companies do business Ethics in work and value system touches every facet of Human Resource. Efficient incorporation of these concepts optimizes the human capital of the organisation.
In this era of global competition, ethics and value system comes as a survival technique, and this paper is an attempt to publicize the tremendous growth opportunity of it as a sustainabilily technique.
The rapid growth of companies globally, poses numerous puzzles. Why it is occurring, and why do people care about it? This paper proposes an explanation for many of these puzzles in terms of the increasing importance of work ethics and value system in the organizations.
Does a gluten-free diet result in nutritional deficiencies? – a review of literature
Authors: Świercz Aleksandra , Żurek Urszula , Tołwiński Ignacy , Kędzierska Zofia , Antkowiak Klaudia , Dadas Klaudia , Małachowska Dominika , Ciecierski-Koźlarek Hubert , Shved Kateryna 
Published: August 2023

Introduction and purpose:
Gluten-free diet have gained immense popularity in recent years, both as a treatment for coeliac disease and as a lifestyle choice for those who believe it is healthier. However, concerns have been raised about potential nutrient inadequacies resulting from the elimination of gluten-containing grains. The purpose of this review is to assess the state of knowledge regarding the impact of a gluten-free diet on nutritional status.
Materials and methods:
A comprehensive search was conducted using electronic database PubMed to identify relevant studies published between 1999 and 2022. Keywords such as "gluten-free diet" and "nutritional deficiencies" were used in combination with Boolean operators to refine the search.
A brief description of the state of knowledge:
Analysis of studies revealed that individuals adhering to a gluten-free diet may be at risk of nutritional deficiencies including micronutrients such as vitamin D, vitamin E, vitamin B complex along with minerals, in particular iron, zinc, calcium, magnesium as well as fibre. Furthermore, higher levels of fat and sugar were observed in the composition of gluten-free products.
Conclusions:
Based on the current body of literature, it is evident that a gluten-free diet results in certain nutritional deficiencies. Individuals following gluten-free diet should be aware of potential risks and take appropriate measures to ensure a well-balanced and nutrient-rich diet. Nutritional guidance should be provided to individuals to address specific nutrient deficiencies associated with a gluten-free diet.
focus on Sjogren’s Dry Eye Disease - pathogenesis, patient management, and new advancements in therapy
Authors: Uram Ewa , Bogacz Rafał , Gaik Magdalena , Magda Inga , Woźniak Justyna , Womperski Karol , Osuch Magdalena 
Published: August 2023

Introduction: Sjogren’s syndrome (SS) is a systemic chronic inflammatory autoimmune disease of unknown etiology that primarily affects exocrine glands. Most commonly Sjogren’s syndrome presents with dryness of the mouth and eyes, but it can also affect major organs and systems of the body and increase the risk of non-Hodgkin lymphoma. Due to non-specific symptoms that pose diagnostic challenges and a lack of standardized screening tools and classification criteria, the global incidence and prevalence of the disease are hard to evaluate. Studies estimate that Sjogren’s syndrome affects between 400,000 to 3.1 million adults worldwide and most likely is a condition significantly underdiagnosed.
Aim of the study: Review of current knowledge about Sjogren’s dry eye disease, underlying pathologies, diagnostic problems, and current treatment options with a focus on the most recent advancements in therapy.
Methods and materials: A review of chosen literature in the PubMed database, MDPI database, and GoogleScholar in the years 2000-2023 was conducted using the following keywords: “Sjogren’s syndrome”, “Sjogren’s syndrome ophthalmology”, “Sjogren’s dry eye syndrome”, “Sjogren’s syndrome associated dry eye”, “Lymphoma in Sjogren’s syndrome”, “Diagnosing Sjogren’s syndrome dry eye”, “Sjogren’s syndrome epidemiology”.
Results: Sjogren’s syndrome is a far from rare autoimmune disease that affects many organs of the body and can significantly lower quality of life and increase mortality and morbidity. Due to its surreptitious symptom onset, Sjogren’s syndrome is commonly underdiagnosed. New diagnostic and treatment modalities for Sjogren’s syndrome dry eye are on the horizon.
Conclusions: Standardized, internationally recognized criteria and a high level of clinical suspiciousness are needed for a timely and accurate diagnosis of Sjogren’s syndrome. Quick diagnosis is a significant facilitating factor for maintaining a high quality of life in Sjogren’s syndrome dry eye.
Coexistence of Slipped Capital Femoral Epiphysis and multiple endocrine neoplasia type 2B (MEN2B) - a case report
Authors: Kędra Kamila , Bielak Maciej , Michalik Izabela , Zarańska Julia , Aab Arkadiusz , Bielak Karolina 
Published: August 2023

Introduction: MEN 2B syndrome is distinguished by the occurrence of medullary thyroid cancer, pheochromocytoma, mucosal neuromas, marfanoid features, and skeletal anomalies, including kyphoscoliosis, joint laxity, pes cavus, and, in a smaller number of cases, slipped capital femoral epiphysis (SCFE).
Case report: We describe a case report of a 15-years-old patient with the diagnosis of the MEN2B syndrome with a rare manifestation of Slipped Capital Femoral Epiphysis (SCFE). A 15-year-old female presented to the orthopedics out-patient department (OPD) with complaints of pain around the right hip and knee and walking with a limp for approximately four months. Additionally, the feeling of enlarged thyroid gland was reported. X-ray confirmed the presence of the SCFE, while thyroid biopsy revealed the presence of medullary thyroid cancer (MTC). Thus, the diagnosis of MEN2B was made.
Conclusion: Slipped capital femoral epiphysis (SCFE) can occasionally be a manifestation of MEN 2B syndrome. It is important for physicians to be aware of this association, as it can contribute to the early detection of a potentially life-threatening condition.
Disease Bundling or Specimen Bundling? Cost- and Capacity-Efficient Strategies for Multidisease Testing with Genetic Assays
Authors: Bish Douglas R. , Bish Ebru K. , El Hajj Hussein 
Published: August 2023

Problem definition: Infectious disease screening can be expensive and capacity constrained. We develop cost- and capacity-efficient testing designs for multidisease screening, considering (1) multiplexing (disease bundling), where one assay detects multiple diseases using the same specimen (e.g., nasal swabs, blood), and (2) pooling (specimen bundling), where one assay is used on specimens from multiple subjects bundled in a testing pool. A testing design specifies an assay portfolio (mix of single-disease/multiplex assays) and a testing method (pooling/individual testing per assay). Methodology/results: We develop novel models for the nonlinear, combinatorial multidisease testing design problem: a deterministic model and a distribution-free, robust variation, which both generate Pareto frontiers for cost- and capacity-efficient designs. We characterize structural properties of optimal designs, formulate the deterministic counterpart of the robust model, and conduct a case study of respiratory diseases (including coronavirus disease 2019) with overlapping clinical presentation. Managerial implications: Key drivers of optimal designs include the assay cost function, the tester’s preference toward cost versus capacity efficiency, prevalence/coinfection rates, and for the robust model, prevalence uncertainty. When an optimal design uses multiple assays, it does so in conjunction with pooling, and it uses individual testing for at most one assay. Although prevalence uncertainty can be a design hurdle, especially for emerging or seasonal diseases, the integration of multiplexing and pooling, and the ordered partition property of optimal designs (under certain coinfection structures) serve to make the design more structurally robust to uncertainty. The robust model further increases robustness, and it is also practical as it needs only an uncertainty set around each disease prevalence. Our Pareto designs demonstrate the cost versus capacity trade-off and show that multiplexing-only or pooling-only designs need not be on the Pareto frontier. Our case study illustrates the benefits of optimally integrated designs over current practices and indicates a low price of robustness.Funding: This work was supported by the National Science Foundation [Grant 1761842].Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2022.0296 .
Examining the factors that influence medication administration errors and the reporting of these among mental health nurses in the hospital setting: a systematic review
Authors: Casey Pearl , Mahony James O , Lehane Elaine , McCarthy Suzanne 
Published: August 2023

Background/Aims A medication administration error is defined as ‘any difference between what the patient received or was supposed to receive and what the prescriber intended in the original order’. Medication administration errors are associated with increased morbidity and mortality. They occur frequently in the mental health setting and pose a serious risk of patient harm. The factors leading to medication administration errors in the mental health care setting is under researched and the potential for mental health services to prevent harm from medication administration error is unknown. The aim of this study was to understand factors that influence medication administration errors, and the reporting of these, among mental health nurses in the mental health hospital setting. Methods A systematic review was conducted following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (2015) checklist. A total of 3625 studies were identified, nine of which were included for final review. The CINAHL, Cochrane, EMBASE, Medline, Medline Ovid, Psych Info and PubMed databases were searched, as well as grey literature. Results Medication administration errors and their reporting are complex, multifaceted and show organisational and individual overlap. Heavy workload, staffing shortages, differing levels of experience, ward dynamics, lack of knowledge, interruptions, communication and patient interaction contributed to the occurrence of medication administration errors. Key factors included rationale on why not to report an error, lack of knowledge regarding how to report, what to report, as well as fear and stigma. Conclusions Many factors lead to the occurrence of a medication administration error or why they are not reported. More education is needed to help reduce medication administration errors. Further research may understand the behavioural patterns of mental health nurses and at-risk behaviour. This may help identify adequate interventions to reduce the risk of medication administration errors in this setting.
DUAL MOBILITY IMPLANTS IN HIGH-RISK PATIENTS AND PERIPROSTHETIC FRACTURE: “A PERFECT STORM”
Authors: Jones Stephen , Raj Sunil , Magan Ahmed 
Published: August 2023

Dual mobility (DM) is most often used by surgeons to reduce instability in high risk patients. NJR data on DM has not demonstrated a reduction in all cause revision and has reported an increase in revision for peri-prosthetic fracture (PPF). The aim of our study was:Report outcome of DM used in high-risk patients including non-revision re-operations (dislocation & PPF).Comparison with conventional bearing THA (cTHA) with local, national and NJR benchmarking data.Retrospective cohort assessment of falls risk for patients receiving DM.Prospective F/U of a DM implant since 2016 and enrolled into Beyond Compliance (BC). Primary outcome measure all-cause revision with secondary outcome including any re-operation and Oxford Hip Score (OHS). All patients were risk stratified and considered high risk for instability. Complications were identified via hospital records, clinical coding linkage, NJR and BC. Benchmarking data for comparison was obtained from same data sources we also considered all B type PPF that occurred with cemented polished taper stem (PTS).159 implants in 154 patients with a mean age 74.0 years and a maximum F/U of 6.7 years. Survivorship for all-cause revision 99.4% (95% CI 96.2–99.8). One femoral only revision. Mean gain in OHS 27.4. Dislocation rate 0.6% with a single event. Patients with a PTS rate of Type B PPF 2.1% requiring revision/fixation. Compared to cTHA this cohort was significantly older (74.0 vs 68.3 years), more co-morbidity (ASA 3 46.5% vs 14.4%) and more non-OA indications (32.4% vs 8.5%). Relative risks for dislocation 0.57 (95%CI 0.08–4.1) and PPF 1.75 (95%CI 0.54–5.72). Every patient had at least one risk factor for falling and >50% of cohort had 4 or more risk factors using NICE tool.The selective use of DM in high-risk patients can reduce the burden of instability. These individuals are very different to the “average” THA patient. A “perfect storm” is created using a high-risk implant combination (DM & PTS) in high-risk falls risk population. This re-enforces the need to consider all patient and implant factors when deciding bearing selection.
EFFECT OF A LEG LENGTH-EVENING DEVICE ON GAIT NORMALITY WHILE WEARING VACUUM ORTHOSES
Authors: Wendlandt R. , Herchenröder M. , Hinz N. , Freitag M. , Schulz A.-P. 
Published: August 2023

Vacuum orthoses are being applied in the care of patients with foot and lower leg conditions, as ankle fractures or sprains. The lower leg is protected and immobilized, which increases mobility. Due to the design, the orthoses lead to a difference in leg length, i.e. the side with the orthosis becomes longer, which changes the gait kinematics. To prevent or mitigate the unfavourable effects of altered gait kinematics, leg length-evening devices (shoe lifts) are offered that are worn under the shoe on the healthy side. Our aim was to evaluate the effect of such a device on the normality of gait kinematics.Gait analysis was conducted with 63 adult, healthy volunteers having signed an informed consent form that were asked to walk on a treadmill at a speed of 4.5km/h in three different conditions:barefoot - as reference for establishing the normality score baselinewith a vacuum orthosis (VACOPed, OPED GmbH, Germany) and a sport shoewith a vacuum orthosis and a shoe lift (EVENup, OPED GmbH, Germany)Data was sampled using the gait analysis system MCU 200 (LaiTronic GmbH, Austria). The positions of the joint markers were exported from the software and evaluated for the joint angles during the gait cycle using custom software (implemented in DIAdem 2017, National Instruments).A normality score using a modification of the Gait Profile Score (GPS) was calculated in every 1%-interval of the gait cycle and evaluated with a Wilcoxon signed rank test.The GPS value was reduced by 0.33° (0.66°) (median and IQR) while wearing the shoe lift. The effect was statistically significant, and very large (W = 1535.00, p < .001; r (rank biserial) = 0.52, 95% CI [0.29, 0.70]).The significant reduction of the GPS value indicates a more normal gait kinematics while using the leg length-evening device on the contralateral shoe. This rather simple and inexpensive device thus might improve patient comfort and balance while using the vacuum orthoses.
Solution-processed halide perovskite microcavity exciton-polariton light-emitting diodes working at room temperature
Authors: Liu Tianyu , Ran Peng , Su Yirong , Chen Zeng , Lai Renchen , Shen Weidong , Ma Yaoguang , Zhu Haiming , Yang Yang (Michael) 
Published: August 2023

Exciton-polaritons offer the potential to achieve electrically pumped perovskite polariton lasers with much lower current thresholds than conventional photonic lasers. While optically pumped exciton-polaritons have been widely studied in halide perovskites, electrically-pumped polaritons remain limited. In this study, we demonstrate the use of a solution-processing strategy to develop halide perovskite polariton light-emitting diodes (LEDs) that operate at room temperature. The strong coupling of excitons and cavity photons is confirmed through the dispersion relation from angle-resolved reflectivity, with a Rabi splitting energy of 64 meV. Our devices exhibit angle-resolved electroluminescence following the low polariton branch and achieve external quantum efficiencies of 1.7%, 3.85%, and 3.7% for detunings of 1.1, −77, and −128  meV, respectively. We also explore devices with higher efficiency of 5.37% and a narrower spectral bandwidth of 6.5 nm through the optimization of a top emitting electrode. Our work demonstrates, to our knowledge, the first room-temperature perovskite polariton LED with a typical vertical geometry and represents a significant step towards realizing electrically pumped perovskite polariton lasers.
Mentalization and Its Use in Schools
Authors: Nišponská Magda 
Published: August 2023

Th is article outlines the current state of theoretical knowledge about mentalization, which appears to be essential for eff ective practice in the teaching profession. Mentalization is the capacity to understand and make sense of our own and others' actions by recognising and giving meaning to intentional mental states, including needs, thoughts, feelings, beliefs, and motivations. It is the understanding of the background of the behaviour – the understanding of the mental states that have led to a certain behaviour. Thanks to mentalization theory, we are now able to think and discuss in more detail what happens between and within people as they interact in diff erent social contexts such as schools. Th ese skills are useful for teachers as they work with children, whose metalizing skills are still developing. At the same time, in their practice, teachers often encounter children who come to school with disruptive behaviours, insecure attachment styles, and negative internal working models of relationships that make the healthy development of mentalizing skills diffi cult. Th is article highlights the importance of mentalization in educational contexts and provides a framework for interventions aimed at increasing mentalization skills among teachers, parents, and students. Empirical evidence has shown that the implementation of mentalization-based programmes in schools can lead to signifi cant improvements in teacherresilience, as well as a reduction of aggressive behaviour among students and an improvement of their academic performance.