bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphine Re-Arranges Chromatin Spatial Architecture of Primate Cortical Neurons
Authors: Wang Liang , Wang Xiaojie , Liu Chunqi , Xu Wei , Kuang Weihong , Bu Qian , Li Hongchun , Zhao Ying , Jiang Linhong , Chen Yaxing , Qin Feng , Li Shu , Wei Qinfan , Liu Xiaocong , Liu Bin , Chen Yuanyuan , Dai Yanping , Wang Hongbo , Tian Jingwei , Cao Gang , Zhao Yinglan , Cen Xiaobo 
Published: May 2023

Abstract
The expression of linear DNA sequence is precisely regulated by the three-dimensional (3D) architecture of chromatin. Morphine-induced aberrant gene networks of neurons have been extensively investigated; however, how morphine impacts the 3D genomic architecture of neurons is still unknown. Here, we applied digestion-ligation-only high-throughput chromosome conformation capture (DLO Hi-C) technology to investigate the effects of morphine on the 3D chromatin architecture of primate cortical neurons. After receiving continuous morphine administration for 90 days on rhesus monkeys, we discovered that morphine re-arranged chromosome territories, with a total of 391 segmented compartments being switched. Morphine altered over half of the detected topologically associated domains (TADs), most of which exhibited a variety of shifts, followed by separating and fusing types. Analysis of the looping events at kilobase-scale resolution revealed that morphine increased not only the number but also the length of differential loops. Moreover, all identified differentially expressed genes from the RNA sequencing data were mapped to the specific TAD boundaries or differential loops, and were further validated for changed expression. Collectively, an altered 3D genomic architecture of cortical neurons may regulate the gene networks associated with morphine effects. Our finding provides critical hubs connecting chromosome spatial organization and gene networks associated with the morphine effects in humans.
Equivalent income versus equivalent lifetime: does the metric matter?
Authors: Onder Harun , Pestieau Pierre , Ponthiere Gregory 
Published: May 2023

Abstract
We examine the effects of the postulated metric on the measurement of well-being, by comparing, in the (income, lifetime) space, two indexes: the equivalent income index and the equivalent lifetime index. The conditions under which the equivalent lifetime index exists are more restrictive than the ones under which the equivalent income index exists, but it is possible to define an alternative equivalent lifetime index, based on two reference income levels, for which the non-existence problem is less acute. Those indexes are also shown to satisfy different properties concerning interpersonal well-being comparisons, which can lead to contradictory rankings. While those incompatibilities arise under distinct indifference maps, we also explore the effects of the metric while relying on a unique indifference map, and show that, even in that case, the postulated metric matters for the measurement of well-being.
Exploring microfoundations and multilevel mechanisms of absorptive capacity in an emerging economy: empirical evidence from a leading car manufacturer
Authors: Kashan Alireza Javanmardi , Mohannak Kavoos , Torres de Oliveira Rui 
Published: May 2023

AbstractPurposeDespite the importance of knowledge processes in building absorptive capacity, we are less clear about the micro-processes of absorptive capacity development and particularly about the role of individuals' knowledge processes.Design/methodology/approachThis study empirically examined, via an in-depth case study, the microfoundations of absorptive capacity and their influence on building absorptive capacity in an automaker across the course of four product innovation projects.FindingsFindings suggested that dynamics in a knowledge environment informed individual-level tacit and explicit knowledge processes. In return, knowledge processes at the individual level informed organizational learning processes and the emergence of knowledge processes at organization level for acquisition, assimilation, transformation, and exploitation of new knowledge.OriginalityThis study contributes to the literature by revealing individuals' knowledge processes from which absorptive capacity emerges. Practically, managers can use the findings of this study to promote certain knowledge processes to develop intended aspects of absorptive capacity at an individual level.
A CLASSIFICATION OF THE WADGE HIERARCHIES ON ZERO-DIMENSIONAL POLISH SPACES
Authors: CARROY RAPHAËL , MOTTO ROS LUCA , SCAMPERTI SALVATORE 
Published: May 2023

Abstract
We provide a complete classification, up to order-isomorphism, of all possible Wadge hierarchies on zero-dimensional Polish spaces using (essentially) countable ordinals as complete invariants. We also observe that although our assignment of invariants is very simple and there are only

$ \aleph _1 $

-many equivalence classes, the above classification problem is quite complex from the descriptive set-theoretic point of view: in particular, there is no Borel procedure to determine whether two zero-dimensional Polish spaces have isomorphic Wadge hierarchies. All results are based on a complete and explicit description of the Wadge hierarchy on an arbitrary zero-dimensional Polish space, depending on its topological properties.
Exploring the Quotidian: An Analysis of Plain-Weave Textiles at Cerro de Oro, Peru, during the Sixth to Tenth Centuries
Authors: Fernandini Parodi Francesca , Varillas Rosa María 
Published: May 2023

AbstractAndean prehispanic textiles are renown for being complex masterpieces made with labor-intensive techniques and high-quality raw materials. Nevertheless, the vast majority of textiles, those used by the population at large, were plain, simple, and without any decoration. We study a sample composed of the most common textiles used by people living at Cerro de Oro in the Cañete Valley, Peru. Our analysis focuses on fiber selection, yarn thickness, and the presence of errors throughout the process of weaving. We discuss relevant aspects of the social process of textile production, such as the role played by plain-weave textiles in different contexts, their use in different types of garments, and the varied ways community members, with particular skill levels, participated in clothing the living and the dead at Cerro de Oro.
Which psychotherapy is most effective and acceptable in the treatment of adults with a (sub)clinical borderline personality disorder? A systematic review and network meta-analysis
Authors: Setkowski Kim , Palantza Christina , van Ballegooijen Wouter , Gilissen Renske , Oud Matthijs , Cristea Ioana A. , Noma Hisashi , Furukawa Toshi A. , Arntz Arnoud , van Balkom Anton J. L. M. , Cuijpers Pim 
Published: May 2023

AbstractA broad range of psychotherapies have been proposed and evaluated in the treatment of borderline personality disorder (BPD), but the question which specific type of psychotherapy is most effective remains unanswered. In this study, two network meta-analyses (NMAs) were conducted investigating the comparative effectiveness of psychotherapies on (1) BPD severity and (2) suicidal behaviour (combined rate). Study drop-out was included as a secondary outcome. Six databases were searched until 21 January 2022, including RCTs on the efficacy of any psychotherapy in adults (⩾18 years) with a diagnosis of (sub)clinical BPD. Data were extracted using a predefined table format. PROSPERO ID:CRD42020175411. In our study, a total of 43 studies (N = 3273) were included. We found significant differences between several active comparisons in the treatment of (sub)clinical BPD, however, these findings were based on very few trials and should therefore be interpreted with caution. Some therapies were more efficacious compared to GT or TAU. Furthermore, some treatments more than halved the risk of attempted suicide and committed suicide (combined rate), reporting RRs around 0.5 or lower, however, these RRs were not statistically significantly better compared to other therapies or to TAU. Study drop-out significantly differed between some treatments. In conclusion, no single treatment seems to be the best choice to treat people with BPD compared to other treatments. Nevertheless, psychotherapies for BPD are perceived as first-line treatments, and should therefore be investigated further on their long-term effectiveness, preferably in head-to-head trials. DBT was the best connected treatment, providing solid evidence of its effectiveness.
Exploring individual variation in Turkish heritage speakers’ complex linguistic productions: Evidence from discourse markers
Authors: Özsoy Onur , Blum Frederic 
Published: May 2023

AbstractResearch on multilingual speakers is often compared to monolingual baselines which are commonly treated as if they were homogeneous across speakers. Despite recent research showing that this homogeneity does not hold, these practices reproduce native-speakerism and monolingualism. Heritage language research, which established itself in the past two decades, is no exemption. Focusing on three predefined linguistic groups, namely Turkish speakers which are framed as monolingual in Turkey as well as two heritage bilingually framed groups in Germany and the USA, we ask: (1) Do heritage speakers of Turkish produce more discourse and fluency markers (FMs) than monolingual speakers? (2) Are the groups homogeneous, or is there wide variation between speakers across groups? We focus on the variation between and within groups using Bayesian Linear Regression with a multilevel model for speakers and heritage groups. Our findings confirm that the use of discourse and FMs is largely defined through individual variation, and not through the belonging to a certain speaker group. By focusing on variation across groups rather than between groups, our study design supports the growing body of literature that questions common heritage language research practices of today and shows alternative paths to understanding heritage grammars.
Implantation de l’Accompagnement-citoyen personnalisé d’intégration communautaire (APIC) : vers l’optimisation de la mise en œuvre de cette approche novatrice visant la participation sociale des aînés
Authors: Gobeil Janie , Gaumond Véronique , Germain Stéphanie , Vézina Audrey , Duguay Anne-Marie , Levasseur Mélanie 
Published: May 2023

RésuméLa présente étude visait à documenter l’implantation de l’Accompagnement-citoyen personnalisé d’intégration communautaire (APIC), lors duquel des bénévoles soutiennent la participation sociale d’aînés, dans des organismes communautaires en identifiant les facteurs favorables et défavorables ainsi que ses conditions essentielles. Soutenu par un devis qualitatif descriptif de type recherche clinique, une rencontre et six entretiens semi-dirigés ont été réalisés afin de documenter cette implantation dans six organismes communautaires œuvrant en milieu urbain au Québec (Canada). Selon les six coordonnatrices de l’APIC, les cinq directeurs généraux et l’agente de recherche, le principal facteur favorable est la conviction des responsables de l’implantation en la valeur ajoutée de l’intervention, incluant sa concordance avec la mission et les valeurs des organismes et les besoins de la population qu’ils desservent. Les facteurs défavorables sont principalement la répartition aléatoire et le temps accordé pour l’implantation. Ces résultats permettront de mieux guider l’implantation de l’APIC à plus grande échelle.
Prediction of the COVID-19 transmission: a case study of Pakistan
Authors: Sabir Qurat Ul An , Shafqat Ambreen , Aslam Muhammad 
Published: May 2023

Abstract
The world has suffered a lot from COVID-19 and is still on the verge of a new outbreak. The infected regions of coronavirus have been classified into four categories: SIRD model, (1) suspected, (2) infected, (3) recovered, and (4) deaths, where the COVID-19 transmission is evaluated using a stochastic model. A study in Pakistan modeled COVID-19 data using stochastic models like PRM and NBR. The findings were evaluated based on these models, as the country faces its third wave of the virus. Our study predicts COVID-19 casualties in Pakistan using a count data model. We’ve used a Poisson process, SIRD-type framework, and a stochastic model to find the solution. We took data from NCOC (National Command and Operation Center) website to choose the best prediction model based on all provinces of Pakistan, On the values of log L and AIC criteria. The best model among PRM and NBR is NBR because when over-dispersion happens; NBR is the best model for modelling the total suspected, infected, and recovered COVID-19 occurrences in Pakistan as it has the maximum log L and smallest AIC of the other count regression model. It was also observed that the active and critical cases positively and significantly affect COVID-19-related deaths in Pakistan using the NBR model.
Redefining caregiver strain for family caregivers in end-of-life care in Hong Kong
Authors: Chow Amy Yin Man , Fordjour Genevieve Ataa , Jiao Keyuan , Jung Nahri , Chan Iris Kwan Ning , Kuok Chak Nam 
Published: May 2023

AbstractObjectivesCaregiving for family members at their end of life is stressful. Caregivers’ strain, burden, or stress has been measured in various geographical and sociodemographic contexts. The concept of stress, burden, and strain are sometimes used interchangeably. By analysing the factor structure of the Chinese version of the Modified Caregiver Strain Index (C-M-CSI), this study aimed to examine the caregiving strain concept and its demographic correlates.MethodsA sample of 453 family caregivers of patients with a terminal illness in Hong Kong was employed. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed. In addition, generalized linear models (GLM) were used to examine the demographic correlates.ResultsThe EFA yielded a 3-factor model termed “Perception of Caregiving,” “Empathetic Strain,” and “Adjustment Demand.” This 3-factor model explained 50% of the variance and showed good internal consistency. The CFA confirmed the 3-factor construct with satisfactory internal reliability (χ2 [61, N = 226] = 108.86, p < 0.001, CFI = 0.96, TLI = 0.95, SRMR = 0.04, and RMSEA = 0.06). Inspired by this factor structure and concepts of stress and strain from engineering discipline, a new model of caregiver strain is proposed. Additionally, family caregivers of non-cancer patients, who were not living with the patient, or younger were associated negatively with different dimensions of caregiver strain.Significance of resultsThe results gave insights into the advancement of the conceptualization of caregiver strain, its multidimensional nature, and process of change, which inform directions for future research and practices.
Germination ecology and response to herbicides of Ludwigia prostrata and their implication for weed control in paddy fields
Authors: Li Tao , Qian Huawei , Yuan Guohui , Fan Jiequn , Guo Shuiliang 
Published: May 2023

AbstractProstrate water primrose is a troublesome weed in rice paddy fields. A study was conducted to determine the influence of environmental and agronomic factors on its emergence. The efficacy of herbicides on this species was also examined. The germination percentage of mature seeds remained above 90% within 180 d after harvest, indicating a low primary dormancy of this species. Light stimulated seed germination. Seeds buried deeper than 0.5 cm did not form seedlings. These results suggest that stale seedbed practices and deep tillage operations can mitigate the occurrence of this species in paddy fields. The optimum temperature for germination varied from 25/15 C to 35/25 C. The osmotic potential and salt concentration needed to inhibit 50% of maximum germination were −0.4 MPa and 197 mM, respectively. Seeds were tolerant to flooding and did not germinate at pH 8 to 10. The preemergence herbicides oxadiazon, oxadiargyl, and butachlor had excellent control efficacy on prostrate water primrose, with a 95.4% to 100% reduction in seedling number and a 99.2% to 100% reduction in biomass, respectively. The postemergence herbicides MCPA-Na + bentazone, bentazone, MCPA-Na, and fluroxypyr applied at the 2- to 3-leaf stage of prostrate water primrose provided a 90.6% to 100% reduction in seedling number and a 99.3% to 100% reduction in biomass. The results of this study can help in developing sustainable and effective integrated weed management strategies for controlling prostrate water primrose in paddy fields.
Caring Through COVID
Authors: Plys Evan , Ahmad Nina , Netten Allegra , Williams Kadija N. , Tyrrell Caitlin J. , Weiskittle Rachel E. , Reddin Shauna , Mitchell Milann , Strong Jessica V. 
Published: May 2023

Abstract: This multisite quality improvement (QI) project reports on a psychotherapy group for family care partners of persons living with neurodegenerative conditions. Following the plan-do-study-act model, a team of geropsychologists iteratively developed, implemented, and refined the 8-week “Caring Through COVID” psychotherapy group across five cycles from January 2021 to April 2022. Participants were 21 spouses or adult children of persons living with neurodegenerative conditions. Across two clinics, participants evidenced moderate improvements in caregiver burden ( d = .59), self-efficacy for caregiving ( d = −.64), and self-efficacy for emotion regulation ( d = −.60). The group was perceived positively by participants. This QI project demonstrates the real-world implementation of a psychotherapy group developed during the COVID-19 pandemic and refined to remain ongoing.
Aggregates of conjugated polymers: bottom-up control of mesoscopic morphology and photophysics
Authors: Kim Chanwoo , Joung Hyeyoung , Kim Hyung Jun , Paeng Keewook , Kaufman Laura J. , Yang Jaesung 
Published: May 2023

AbstractConjugated polymer (CP) aggregates have been the focus of considerable research, as these mesoscopic entities, compared with single CP chains, provide environments more analogous to those present in polymer-based optoelectronics in terms of the complexity of morphology and chain interactions; thereby, such aggregates hold the potential to provide insights into structure–function relationships highly relevant to optoelectronic device efficiency and stability. This review article highlights single-aggregate spectroscopy studies of CP aggregates based on a combination of solvent vapor annealing and single-molecule fluorescence techniques and draws mesoscopic connections between morphology, electronic coupling, and photophysics in CPs. This molecular-level understanding will pave the way for the bottom-up control of optoelectronic properties from the molecular to the device-length scale.
On-chip spin-photon entanglement based on photon-scattering of a quantum dot
Authors: Chan Ming Lai , Tiranov Alexey , Appel Martin Hayhurst , Wang Ying , Midolo Leonardo , Scholz Sven , Wieck Andreas D. , Ludwig Arne , Sørensen Anders Søndberg , Lodahl Peter 
Published: May 2023

AbstractThe realization of on-chip quantum interfaces between flying photons and solid-state spins is a key building block for quantum-information processors, enabling, e.g., distributed quantum computing, where remote quantum registers are interconnected by flying photons. Self-assembled quantum dots integrated into nanostructures are one of the most promising systems for such an endeavor thanks to their near-unity photon-emitter coupling and fast spontaneous emission rate. Here we demonstrate high-fidelity on-chip entanglement between an incoming photon and a stationary quantum-dot hole spin qubit. The entanglement is induced by sequential scattering of the time-bin encoded photon interleaved with active spin control within a microsecond, two orders of magnitude faster than those achieved in other solid-state platforms. Conditioning on the detection of a reflected photon renders the entanglement fidelity immune to the spectral wandering of the emitter. These results represent a major step towards realizing a quantum node capable of interchanging information with flying photons and on-chip quantum logic, as required for quantum networks and quantum repeaters.
A web-based system to determine risk of investment in international rail construction projects
Authors: Yuan Ting 
Published: May 2023

AbstractManual evaluation of investment risk make results and solutions are not timely. The objective of the study is to explore intelligent risk data collecting and risk early warning of international rail construction. First, this study has identified risk variables by content mining. Second, risk thresholds are calculated by the quantile method based on data from 2010 to A.D. 2019. Third, this study has developed risk early warning system by the gray system theory model, the matter-element extension method and the entropy weight method. Fourth, the risk early warning system is verified using Nigeria coastal railway project in Abuja. This study found that: (1) the framework of the developed risk warning system contains a software and hardware infrastructure layer, a data collection layer, an application support layer, and an application layer. (2) 37 investment risk variables are recognized; (3) 12 risk variables thresholds intervals are not equally divided between 0 and 1, the others are evenly distributed; (4) based on the application of Nigeria coastal railway project in Abuja, the system verification results are consistent with real situations, which is shown that risk early warning system is reasonable and feasible. These findings offer a good reference for intelligent risk management.
A versatile method to fingerprint and compare the oxidative behaviour of lipids beyond their oxidative stability
Authors: Pizzimenti Silvia , Bernazzani Luca , Duce Celia , Tinè Maria Rosaria , Bonaduce Ilaria 
Published: May 2023

AbstractIn this work we propose the use of isothermal thermogravimetry to evaluate the oxidative stability of a lipid and to evaluate how the glyceride composition affects the entire oxidative process, to quantify the oxidation undertaken by the lipid, and numerically compare the oxidative behaviour of different lipids. The innovative aspect of the present method lies in the acquisition of a prolonged “oxygen uptake” curve (4000–10,000 min) of a lipid under oxygen and in the development of a semi-empirical fitting equation for the experimental data. This provides the induction period (oxidative stability), and allows to evaluate the rate of oxidation, the rate and the magnitude of oxidative degradation, the overall mass loss and the mass of oxygen taken by the lipid upon time. The proposed approach is used to characterize the oxidation of different edible oils with different degrees of unsaturation (linseed oil, sunflower oil, and olive oil) as well as chemically simpler compounds used in the literature to model the autoxidation of vegetable oils and lipids in general: triglycerides (glyceryl trilinolenate, glyceryl trilinoleate and glyceryl trioleate) and methyl esters (methyl linoleate and methyl linolenate). The approach proves very robust and very sensitive to changes in the sample composition.