bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low‐rank motion correction for accelerated free‐breathing first‐pass myocardial perfusion imaging
Authors: Cruz Gastao , Hua Alina , Munoz Camila , Ismail Tevfik Fehmi , Chiribiri Amedeo , Botnar René Michael , Prieto Claudia 
Published: March 2023

PurposeDevelop a novel approach for accelerated 2D free‐breathing myocardial perfusion via low‐rank motion‐corrected (LRMC) reconstructions.MethodsMyocardial perfusion imaging requires high spatial and temporal resolution, despite scan time constraints. Here, we incorporate LRMC models into the reconstruction‐encoding operator, together with high‐dimensionality patch‐based regularization, to produce high quality, motion‐corrected myocardial perfusion series from free‐breathing acquisitions. The proposed framework estimates beat‐to‐beat nonrigid respiratory (and any other incidental) motion and the dynamic contrast subspace from the actual acquired data, which are then incorporated into the proposed LRMC reconstruction. LRMC was compared with iterative SENSitivity Encoding (SENSE) (itSENSE) and low‐rank plus sparse (LpS) reconstruction in 10 patients based on image‐quality scoring and ranking by two clinical expert readers.ResultsLRMC achieved significantly improved results relative to itSENSE and LpS in terms of image sharpness, temporal coefficient of variation, and expert reader evaluation. Left ventricle image sharpness was approximately 75%, 79%, and 86% for itSENSE, LpS and LRMC, respectively, indicating improved image sharpness for the proposed approach. Corresponding temporal coefficient of variation results were 23%, 11% and 7%, demonstrating improved temporal fidelity of the perfusion signal with the proposed LRMC. Corresponding clinical expert reader scores (1–5, from poor to excellent image quality) were 3.3, 3.9 and 4.9, demonstrating improved image quality with the proposed LRMC, in agreement with the automated metrics.ConclusionLRMC produces motion‐corrected myocardial perfusion in free‐breathing acquisitions with substantially improved image quality when compared with iterative SENSE and LpS reconstructions.
The test−retest reproducibility of the multiple array probe Leiden in men with lower urinary tract symptoms
Authors: Beverini Martina , Goes Selma , Witte Lambertus P. W. , van Koeveringe Gommert A. , van der Laan Nienke , Knol‐de Vries Grietje E. , Blanker Marco H. 
Published: March 2023

AbstractBackgroundWe aimed to study the test–retest reliability of the Multiple Array Probe Leiden (MAPLe), a multiple electrode probe designed to acquire and discriminate electromyography signals in the pelvic floor muscles, in men with lower urinary tract symptoms (LUTS).MethodsAdult male patients with LUTS with sufficient knowledge of Dutch language, but without complications (e.g., urinary tract infection), or previous urologic cancer and/or urologic surgery were enrolled. In the initial study, next to physical examination and uroflowmetry, all men underwent MAPLe assessment at baseline and after 6 weeks. Second, participants were reinvited for a new assessment using a stricter protocol. A time interval of 2 h (M2) and 1 week (M3) after baseline (M1) allowed the calculation of the intraday agreement (M1 vs. M2), and the interday agreement (M1 vs. M3) for all 13 MAPLe variables.ResultsThe outcomes of the initial study in 21 men suggested a poor test−retest reliability. The second study in 23 men showed a good test−retest reliability with intraclass correlations ranging from 0.61 (0.12−0.86) to 0.91 (0.81−0.96). The agreement was generally higher for the intraday determinations than for the interday determinations.ConclusionsThis study revealed a good test−retest reliability of the MAPLe device in men with LUTS, when using a strict protocol. With a less strict protocol, the test−retest reliability of MAPLe was poor in this sample. To make valid interpretations of this device in a clinical or research setting, a strict protocol is needed.
Loss to Follow‐up in Head and Neck Cancer: A Systematic Review of Randomized Controlled Trials
Authors: Sawaf Tuleen , Quinton Brooke A. , Moss Gabriel , Yaffe Noah M. , Quereshy Humzah A. , Cabrera‐Aviles Claudia , Fowler Nicole , Li Shawn , Thuener Jason E. , Lavertu Pierre , Rezaee Rod P. , Teknos Theodoros N. , Tamaki Akina 
Published: March 2023

AbstractObjectiveTo evaluate the reporting and rates of loss to follow‐up (LTFU) in head and neck cancer (HNC) randomized controlled trials based in the United States.Data SourcesPubmed/MEDLINE, Cochrane, Scopus databases.Review MethodsA systematic review of titles in Pubmed/MEDLINE, Scopus, and Cochrane Library was performed. Inclusion criteria were US‐based randomized controlled trials focused on the diagnosis, treatment, or prevention of HNC. Retrospective analyses and pilot studies were excluded. The mean age, patients randomized, publication details, trial sites, funding, and LTFU data were recorded. Reporting of participants through each stage of the trial was documented. Binary logistic regression was performed to evaluate associations between study characteristics and reporting LTFU.ResultsA total of 3255 titles were reviewed. Of these, 128 studies met the inclusion criteria for analysis. A total of 22,016 patients were randomized. The mean age of participants was 58.6 years. Overall, 35 studies (27.3%) reported LTFU, and the mean LTFU rate was 4.37%. With the exception of 2 statistical outliers, study characteristics including publication year, number of trial sites, journal discipline, funding source, and intervention type did not predict the odds of reporting LTFU. Compared to 95% of trials reporting participants at eligibility and 100% reporting randomization, only 47% and 57% reported on withdrawal and details of the analysis, respectively.ConclusionThe majority of clinical trials in HNC in the United States do not report LTFU, which inhibits the evaluation of attrition bias that may impact the interpretation of significant findings. Standardized reporting is needed to evaluate the generalizability of trial results to clinical practice.
Comparison of Preoperative DOI Estimation in Oral Tongue Cancer With cN0 Disease
Authors: Au Vivienne H. , Miller Lauren E. , Deschler Daniel G. , Lin Derrick T. , Richmon Jeremy D. , Varvares Mark A. 
Published: March 2023

AbstractObjectiveTo understand the accuracy of pre‐ and intraoperative estimation of tumor depth of invasion (DOI).Study DesignA retrospective case‐control study.SettingPatients who presented at 1 institution with oral tongue squamous cell carcinoma that underwent oncologic resection between 2017 and 2019 were identified.MethodsPatients that met the inclusion criteria were included. Patients with nodal, distant, or recurrent disease, prior history of head and neck cancer, or preoperative tumor assessment and/or final histopathology that did not include DOI were excluded. Preoperative DOI estimation and technique and pathology reports were obtained. Our primary outcome was the sensitivity and specificity of DOI estimation modalities including full‐thickness biopsy (FTB), manual palpation (MP), punch biopsy (PB), and intraoperative ultrasound (IOUS).ResultsTumor DOI was assessed quantitatively preoperatively in 40 patients by FTB (n = 19, 48%), MP (n = 17, 42%), or PB (n = 4, 10%). Additionally, 19 patients underwent IOUS to assess DOI. The sensitivities of FTB, MP, and IOUS for DOI ≥ 4 mm were 83% (confidence interval [CI]: 44%‐97%), 83% (CI: 55%‐95%), and 90% (CI: 60%‐98%), respectively, and the specificities were 85% (CI: 58%‐96%), 60% (CI: 23%‐88%), and 78% (CI: 45%‐94%).ConclusionOur study demonstrated that DOI assessment tools measured had similar sensitivity and specificity in stratifying patients with DOI ≥4 mm, with no statistically superior diagnostic test. Our results support the need for additional research into nodal disease prediction and continued refinement of ND decisions with respect to DOI.
Ketamine use for management of vaso‐occlusive pain in pediatric sickle cell disease
Authors: Harris Emily M. , Vilk Emily , Donado Carolina , Williams Alexis , Heeney Matthew M. , Solodiuk Jean , Greco Christine , Archer Natasha M. 
Published: March 2023

AbstractBackgroundTypical sickle cell disease (SCD) vaso‐occlusive pain episode (VOE) management includes opioids, which are often inadequate and can be associated with significant side effects. Ketamine, a dissociative anesthetic, is a potentially effective adjunct to VOE management.ObjectivesThis study aimed to characterize ketamine use for VOE management in pediatric SCD.MethodThis retrospective case series summarizes a single‐center experience regarding the use of ketamine for inpatient management of pediatric VOE in 156 admissions from 2014 to 2020.ResultsContinuous low‐dose ketamine infusion was most commonly prescribed to adolescents and young adults as an adjunct to opioids (median starting dose 2.0 μg/kg/min; median maximum dose 3.0 μg/kg/min). Ketamine was started a median of 13.7 hours after admission. Median ketamine infusion duration was 3 days. In most encounters, ketamine infusion was discontinued prior to opioid patient‐controlled analgesia (PCA) discontinuation. The majority of encounters (79.3%) had a reduction in either PCA dose, continuous opioid infusion, or both while receiving ketamine. Low‐dose ketamine infusion was associated with side effects noted in 21.8% (n = 34) of encounters. The most common side effects included dizziness (5.6%), hallucinations (5.1%), dissociation (2.6%), and sedation (1.9%). There were no reports of ketamine withdrawal. Most patients who received ketamine went on to receive it again during a subsequent admission.ConclusionFurther study is needed to determine the optimal timing of ketamine initiation and dosing. The variability of ketamine administration highlights the need for standardized protocols for ketamine use in VOE management.
Carbon‐glass reinforced epoxy hybrid composites for crashworthy structural applications
Authors: El Aal Mohamed Ibrahim Abd , Awd Allah Mahmoud M. , Abd El‐baky Marwa A. 
Published: March 2023

AbstractThe goal of this work is to experimentally explore the crashworthiness performance and the deformation history of hybrid thin‐walled composite tubes. Glass (G)/carbon (C) reinforced epoxy circular specimens were prepared by wet wrap using hand lay‐up technique and then subjected to quasi‐static axial compressive loads to examine the impact of the hybridization process and stacking sequences on the crashworthiness performance and the deformation history. Crush indicators, that is, the initial peak force (), absorbed energy (AE), specific absorbed energy (SEA) of the designed tubes were assessed. The specimen's failure modes were discussed. Cost analysis for the proposed materials was carried out. According to the experimental findings, the hybridization and stacking order significantly influence the crashworthiness performance and failure mode of G/C reinforced epoxy composite tubes. C/2G/2C/2G/C hybrid is recommended as an energy absorber material for automobiles.
Comparison of mechanical properties of the Type 1 and Type 2 composite hydraulic cylinder designs: A numerical study
Authors: Coskun Taner , Sahin Omer Sinan 
Published: March 2023

AbstractHydraulic cylinders can reach enormous sizes depending on the working pressure and application areas. These structures, which are typically fabricated using traditional steels, can be quite heavy, which can cause a number of issues, particularly low system efficiency and fuel performance. A Type 1 composite hydraulic cylinder (CHC) with geodesic dome trajectories was created in our earlier work, and the effects of composite material utilization on the structural weight and mechanical responses were examined. Furthermore, the applicability of the geodesic dome to the CHCs was examined, and the benefits and drawbacks of using the dome profile were found. A Type 2 CHC was created in the current study, and the structural performances of Type 1 and Type 2 CHCs were compared. In this regard, numerical analyses were done to assess the mechanical responses and structural performance of a Type 2 CHC. Additionally, utilizing response surface methodology (RSM), the design parameters were optimized. The outputs of the current study were then verified by comparing the outcomes of statistical‐based RSM and FEM examinations. As a result, the structural weights for both designs were compared with steel hydraulic cylinders of the same strength, and it was revealed that Type 1 and Type 2 CHCs were 53.78% and 38.42% lighter than steel ones, respectively. In addition, the advantages and disadvantages of the design types were discussed, and thus the optimum design was determined by considering the application areas and requirements.
Full‐field hygroscopic characterization of tough 3D‐printed supramolecular hydrogels
Authors: Vonk N. H. , van Adrichem S. C. A. , Wu D. J. , Dankers P. Y. W. , Hoefnagels J. P. M. 
Published: March 2023

AbstractChain‐extended ureido‐pyrimidinone poly(ethylene glycol) (CE‐UPy‐PEG) is a supramolecular hydrogel with excellent mechanical properties and shape memory capabilities, making it highly suitable for 3D printing of complex biomimetic structures to mimic biomaterials. However, its transient hygroexpansion response under environmental change, specifically relative humidity (RH), which is strongly affected by the supramolecular sub‐structure, is poorly understood. Therefore, a high‐precision full‐field fiber‐swelling methodology is applied to 3D‐printed CE‐UPy‐PEG fibers, enabling investigation of the influence of PEG chain length (1.5, 3, and 10 kg/mol studied here) and RH rate from wet to dry on the longitudinal and transverse surface strain evolution during multiple RH cycles. The PEG length directly influences the fibers' hygroscopic properties, because only CE‐UPy‐PEG3k and CE‐UPy‐PEG10k exhibit a phase transformation from semicrystalline to amorphous at higher RH levels, which is fully described by a phenomenological phase transformation model. Furthermore, all fibers display cyclic repeatability (shape memory), increased swelling for longer PEG chains and lower RH rate, and disappearance of sub‐millimeter‐sized tube‐like voids after wetting.
Remediation of chloroform in fine‐textured soil using zero‐valent iron
Authors: Murata Alison P. , Siddique Tariq , Jobson Allen M. , Kuznetsova Alsu , Dhar Amalesh , Naeth M. Anne 
Published: March 2023

AbstractChloroform, a probable human carcinogen, is mainly produced anthropogenically for industrial use and may be released to the environment from a large number of sources related to its manufacture and use, including pulp and paper mills, hazardous waste sites, and sanitary landfills. Remediation of chloroform through conventional technologies has been met with limited success due to the conditions required and the formation of hazardous substances such as dichloromethane. The objective of this study was to investigate chloroform reduction in multicontaminated fine‐textured soil using zero‐valent iron (Fe0) in anaerobic microcosms. Four amended matrices were tested: simple matrix control (glass beads), soil matrix control (glass beads + soil), Fe0 in a simple matrix (glass beads + Fe0), and Fe0 in a soil matrix (soil + Fe0). Headspace chloroform and its transformation products dichloromethane, chloromethane, and methane were measured over 230 days and during short intervals in the initial 3 days. Chloroform (~0.3 mM initial mass) persisted in both control microcosms but was completely transformed in microcosms containing soil + Fe0 by 12 h and glass beads + Fe0 by 48 h. Reductive dechlorination of chloroform occurred with simultaneous production of dichloromethane (~0.11 to 0.14 mM mass) and chloromethane (~0.02 to 0.13 mM mass). Little methane (~0.07 to 0.26 μM mass) production as an end product of chloroform reduction was observed in microcosms amended with Fe0. Produced dichloromethane and chloroform almost disappeared by 230 days. The results showed a complete chloroform transformation pathway that has good potential for the remediation of chlorinated compounds in fine‐textured soil. The role of soil clay minerals in redox reactions can be further investigated to improve the reductive dechlorination of chlorinated compounds in contaminated environments.
Novel Mg‐ and Ga‐doped ZnO/Li‐Doped Graphene Oxide Transparent Electrode/Electron‐Transporting Layer Combinations for High‐Performance Thin‐Film Solar Cells
Authors: Kim Jihun , Jang Jun Sung , Shin Seung Wook , Park Hyeonghun , Jeong Woo‐Lim , Mun Seung‐Hyun , Min Jung‐Hong , Ma Jiyoung , Heo Jaeyeong , Lee Dong Seon , Woo Jung‐Je , Kim Jin Hyeok , Kim Hyeong‐Jin 
Published: March 2023

AbstractHerein, a novel combination of Mg‐ and Ga‐co‐doped ZnO (MGZO)/Li‐doped graphene oxide (LGO) transparent electrode (TE)/electron‐transporting layer (ETL) has been applied for the first time in Cu2ZnSn(S,Se)4 (CZTSSe) thin‐film solar cells (TFSCs). MGZO has a wide optical spectrum with high transmittance compared to that with conventional Al‐doped ZnO (AZO), enabling additional photon harvesting, and has a low electrical resistance that increases electron collection rate. These excellent optoelectronic properties significantly improved the short‐circuit current density and fill factor of the TFSCs. Additionally, the solution‐processable alternative LGO ETL prevented plasma‐induced damage to chemical bath deposited cadmium sulfide (CdS) buffer, thereby enabling the maintenance of high‐quality junctions using a thin CdS buffer layer (≈30 nm). Interfacial engineering with LGO improved the Voc of the CZTSSe TFSCs from 466 to 502 mV. Furthermore, the tunable work function obtained through Li doping generated a more favorable band offset in CdS/LGO/MGZO interfaces, thereby, improving the electron collection. The MGZO/LGO TE/ETL combination achieved a power conversion efficiency of 10.67%, which is considerably higher than that of conventional AZO/intrinsic ZnO (8.33%).
Recent progress of dendrite‐free stable zinc anodes for advanced zinc‐based rechargeable batteries: Fundamentals, challenges, and perspectives
Authors: Wang Xiao , Sun Chenglin , Wu Zhong‐Shuai 
Published: March 2023

AbstractZinc‐based batteries are a very promising class of next‐generation electrochemical energy storage systems, with high safety, eco‐friendliness, abundant resources, and the absence of rigorous manufacturing conditions. However, practical applications of zinc‐based rechargeable batteries are impeded by the low Coulombic efficiency, inferior cyclability, and poor rate capability, due to the instability of zinc anode. Herein, effective strategies for dendrite‐free zinc anode are symmetrically reviewed, especially highlighting specific mechanisms, delicate design of electrode and current collectors, controlled electrode|electrolyte interface, ameliorative electrolytes, and advanced separators design. First, the particular mechanisms of dendrites formation and the associated fundamentals of the stable Zn metal anodes are presented elaborately. Then, recent key strategies for dendrites prevention and hydrogen evolution reaction suppression are categorized, discussed, and analyzed in detail in view of the electrodes, electrolytes, and separators. Finally, the challenging perspectives and major directions of stable zinc anodes are briefly discussed for further industrialization and commercialization of zinc‐based rechargeable batteries.
External field–assisted batteries toward performance improvement
Authors: Wang Wanwan , Lu Yi‐Chun 
Published: March 2023

AbstractRechargeable batteries are essential for the increased demand for energy storage technologies due to their ability to adapt intermittent renewable energies into electric devices, such as electric vehicles. To boost the battery performance, applying external fields to assist the electrochemical process has been developed and exhibits significant merits in energy efficiency and cycle stability enhancement. This perspective focuses on recent advances in the development of external field–assisted battery technologies, including photo‐assisted, magnetic field–assisted, sound field–assisted, and multiple field–assisted. The working mechanisms of external field–assisted batteries and their challenges and opportunities are highlighted.
A systematic literature review of sociotechnical systems in systems engineering
Authors: Polojärvi Dana , Palmer Erika , Dunford Charlotte 
Published: March 2023

AbstractSystems engineers use the term sociotechnical system in academic literature and in their practice. Sociotechnical systems are gaining more attention as systems engineers aspire to address the social elements of their systems engineering practice as well as societal challenges, such as those included in the International Council on Systems Engineering (INCOSE) Vision 2035. Even though there is a basic working definition of sociotechnical system in the Systems Engineering Book of Knowledge (SEBoK), use of the term varies in systems engineering literature depending on application domain. As systems engineering research and practice venture into social domains, it is critical that systems engineers have a shared understanding of terms they use as a foundation of knowledge and practice. To contribute to this foundation, this study is a systematic literature review of how the term sociotechnical system is used in systems engineering literature. We used the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) methodological framework and Web of Science (WoS) for conducting the systematic literature review. We only included peer‐reviewed systems engineering academic papers in this study, and these papers had to either explicitly define the term or implicitly define it by context in the paper. In total, 61 papers were included after inclusion criteria were met, and these were evaluated and synthesized into definition categories. Evaluation and synthesis were conducted according to the PRISMA framework by the study authors in order to manage bias. We found that most papers use sociotechnical system generically as a system that includes social (people) and technical elements. Papers with more refined definitions of sociotechnical system stem from two distinct theoretical traditions: ergonomics/safety and philosophy of engineering. We do not aim to propose a single, normative definition of sociotechnical system. This study is limited by including only systems engineering literature since sociotechnical system has established definitions in other disciplines (e.g., social sciences disciplines). However, the outcome of this study provides systems engineers with documented understanding of how the term sociotechnical system is used within systems engineering.
Life‐cycle cost‐oriented multiobjective optimization of composite frames considering the slab effect
Authors: Lin Yongjun , Zhang Xianzhao 
Published: March 2023

SummaryThe life‐cycle cost‐oriented design philosophy is a promising tool for building resilient cities as it helps in gaining insights into the impact of hazard‐induced damage and repair of civil and infrastructure systems. In this study, a socioeconomic parameter‐independent practical formulation was introduced for life‐cycle cost analysis by combining the economic loss rate associated with different damage limit states and cloud analysis‐based probabilistic seismic demand model. A framework for life‐cycle cost analysis‐based seismic design optimization was proposed using an emerging nature‐inspired algorithm, namely, the multiobjective cuckoo search. By considering an eight‐story prototype composite frame, the framework was used to determine the trade‐off design alternatives between competing optimization objectives. Conventional and improved fiber models were developed to comparatively evaluate the influence of the slab spatial composite effect on Pareto optimal designs. The key drivers of change in three cost indicators were identified using generalized linear models. The result indicates that the overstrength factor is the critical design parameter affecting the initial construction, seismic damage, and life‐cycle costs, with statistical significance at the 0.001 level.