bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interfacility Transfer of Uninsured vs Insured Patients With ST-Segment Elevation Myocardial Infarction in California
Authors: Ward Michael J. , Nikpay Sayeh , Shermeyer Andrew , Nallamothu Brahmajee K. , Rokos Ivan , Self Wesley H. , Hsia Renee Y. 
Published: June 2023

ImportanceInsurance status has been associated with whether patients with ST-segment elevation myocardial infarction (STEMI) presenting to emergency departments are transferred to other facilities, but whether the facility’s percutaneous coronary intervention capabilities mediate this association is unknown.ObjectiveTo examine whether uninsured patients with STEMI were more likely than patients with insurance to experience interfacility transfer.Design, Setting, and ParticipantsThis observational cohort study compared patients with STEMI with and without insurance who presented to California emergency departments between January 1, 2010, and December 31, 2019, using the Patient Discharge Database and Emergency Department Discharge Database from the California Department of Health Care Access and Information. Statistical analyses were completed in April 2023.ExposuresPrimary exposures were lack of insurance and facility percutaneous coronary intervention capabilities.Main Outcomes and MeasuresThe primary outcome was transfer status from the presenting emergency department of a percutaneous coronary intervention–capable hospital, defined as a facility performing 36 percutaneous coronary interventions per year. Multivariable logistic regression models with multiple robustness checks were performed to determine the association of insurance status with the odds of transfer.ResultsThis study included 135 358 patients with STEMI, of whom 32 841 patients (24.2%) were transferred (mean [SD] age, 64 [14] years; 10 100 women [30.8%]; 2542 Asian individuals [7.7%]; 2053 Black individuals [6.3%]; 8285 Hispanic individuals [25.2%]; 18 650 White individuals [56.8%]). After adjusting for time trends, patient factors, and transferring hospital characteristics (including percutaneous coronary intervention capabilities), patients who were uninsured had lower odds of experiencing interfacility transfer than those with insurance (adjusted odds ratio, 0.93; 95% CI, 0.88-0.98; P = .01).Conclusions and RelevanceAfter accounting for a facility’s percutaneous coronary intervention capabilities, lack of insurance was associated with lower odds of emergency department transfer for patients with STEMI. These findings warrant further investigation to understand the characteristics of facilities and outcomes for uninsured patients with STEMI.
Spiroplasmataceae
Authors: Gasparich Gail E. , Brown Daniel R. 
Published: June 2023

Abstract

Spi.ro.plas.ma.ta'.ce.ae. N.L. neut. n.
Spiroplasma
, −
atos
, type genus of the family; −
aceae
, ending to denote a family; N.L. fem. pl. n.
Spiroplasmataceae
, the
Spiroplasma
family.

Tenericutes / Mollicutes / Entomoplasmatales / Spiroplasmataceae

Cells are helical (∼300 nm in diameter) during exponential growth, with rotatory, flexional, and translational motility. Genome size is variable: 780–2220 kb. DNA G + C content ranges from 24–31% (mol%). The temperature growth range varies among species from 5 to 41°C, with the optimum usually in the range of 30 to 32°C. Variable sterol requirement for growth. Procedures for determining sterol requirement are as described for the Family
Entomoplasmataceae
. Possess a phosphoenolpyruvate phosphotransferase system for glucose uptake. Reduced nicotinamide adenine dinucleotide (NADH) oxidase activity is located only in the cytoplasm. Unable to synthesize fatty acids from acetate. Hydrolysis of arginine is variable. Other characteristics are as described for the class and order.

DNA G + C content (mol%)
: 24–31 (
T
m
, Bd).

Type genus
:
Spiroplasma
Saglio et al. 1973
AL
.
Erythrobacteraceae
Authors: Xu Xue‐Wei , Xu Lin , Zhang Yu 
Published: June 2023

Abstract

E.ry.thro.bac.te.ra'ceae. N.L. masc. n.
Erythrobacter
, type genus of the family; L. fem. pl. n. suff. ‐
aceae
, ending to denote a family; N.L. fem. pl. n.
Erythrobacteraceae
, the Erythrobacter family.

Pseudomonadota / Alphaproteobacteria / Sphingomonadales / Erythrobacteraceae

Cells are Gram‐stain‐negative rods, cocci, or ellipsoids. Several species are motile. Aerobic or facultatively anaerobic. The dominant respiratory quinone is ubiquinone‐10 (Q‐10). The major polar lipids are phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and glycosphingolipid (SGL). The cellular fatty acid profiles are dominated by unsaturated fatty acids including heptadecenoic acid (C
17 : 1
) and octadecenoic acid (C
18 : 1
). The family forms a monophyletic cluster in neighbor‐joining phylogenetic analyses of the 16S rRNA gene, while its genus discriminations are based on phylogenomic and genomic similarity analysis. It currently accommodates 19 genera. Members of the family
Erythrobacteraceae
were isolated from various habitats, including marine, terrestrial and freshwater environments.

DNA G + C content (mol%)
: 54–74 (by genome, HPLC or
T
m
).

Type genus
:
Erythrobacter
Shiba and Simidu 1982
VP
.
Photobacterium
Authors: Labella Alejandro M. , Borrego Juan J. 
Published: June 2023

Abstract

Pho.to.bac.te'ri.um. Gr. neut. n.
phôs
, light; Gr. neut. dim. n.
bakterion
, a small rod; N.L. neut. n.
Photobacterium
, light (‐producing) bacterium.

Proteobacteria / Gammaproteobacteria / Vibrionales / Vibrionaceae / Photobacterium

The genus
Photobacterium
contains 37 species with validated names and 3 species whose names have not been validated. Cells are short bacilli Gram‐stain negative, and nonsporulated. Facultatively anaerobic. Require NaCl for growth (optimal concentration 1–3%). Several species present bioluminescence. Some of them are piezophilic and others are psychrophilic. Isolated from marine environment (seawater and sediment), associated with aquatic animals (mutualism relationships), but some are pathogens for poikilothermic and homeothermic animals.

DNA G + C content (mol%)
: 38.5–53.6.

Type species
:
Photobacterium phosphoreum
Beijerinck 1889
AL
(basonym:
Micrococcus phosphoreus
Cohn 1878).
Perexilibacter
Authors: Yokota Akira 
Published: June 2023

Abstract

Pe.rex.i.li.bac'ter. L. adj.
perexilis
, very slender; N.L. masc. n.
bacter
(equivalent of Gr. neut. n.
baktron
), rod or staff; N.L. masc. n.
Perexilibacter
, very slender rod, referring to its cell shape.

Bacteroidota / Flavobacteria / Flavobacteriales / Flammeovirgaceae / Perexilibacter

The genus
Perexilibacter
accommodates a strictly aerobic, Gram‐stain negative, gliding, dull‐orange‐pigmented, rod‐shaped bacterium, which was isolated from marine sediment. The genus
Perexilibacter
belongs to the family
Flammeovirgacee
of the phylum
Bacteroidota. Perexilibacter aurantiacus
could be differentiated phenotypically and physiologically from recognized members of the family
Flammeovirgaceae
. MK‐7 is the major menaquinone and iso‐C
15:0,
C
16:1
ω7
c
,
and C
16:1
ω5
c
are the major fatty acids. Known habitat is marine sediments.

DNA G + C content (mol%)
: 43.0 (HPLC).

Type species
:
Perexilibacter aurantiacus
Yoon et al. 2007
VP
.
Catelliglobosispora
Authors: Trujillo Martha E. , Riesco Raúl 
Published: June 2023

Abstract

Ca.tel.li.glo'bo.si.spo'ra. L. fem. dim. n.
catella
, small chain; L. masc. adj.
globosus
, spherical; Gr. fem. n.
spora
, a seed and in biology a spore; N.L. fem. n.
Catelliglobosispora
, small chain and spherical spores (organism forming).

Actinomycetota / Actinomycetes / Micromonosporales / Micromonosporaceae / Catelliglobosispora

Gram‐stain‐positive, aerobic, filamentous bacteria that produce nonfragmenting, branched vegetative hyphae. Short chains of cylindrical shape, nonmotile spores, and globose bodies arise from the substrate mycelium. Cream to light yellow substrate mycelium is produced but soluble pigments are not reported. Catalase positive and urease negative. Grows between 20–37°C, at pH 6–9, and on media supplemented with 1% NaCl (w/v). Chemoorganotrophic. The diagnostic cell wall amino acid is
meso
‐DAP and MK‐10(H
4
) is the major menaquinone. The genome size is 7.69 Mb and the G + C content of the type strain is 64.4%.

The genus
Catelliglobosispora
comprises only one species,
C. koreensis,
and is phylogenetically related to the genera
Allocatelliglobosispora
,
Allorhizocola
,
Catellatospora
,
Hamadaea
, and
Rhizocola
; all members of the family
Micromonosporaceae
.

DNA G
+
C content
(%): 64.4 (WGS).

Type species
:
Catelliglobosispora koreensis
Ara et al. 2008
VP
emend. Nouioui et al. 2018.
Trinickia
Authors: los Santos Paulina Estrada‐de 
Published: June 2023

Abstract

Tri.nick'i.a. N.L. fem. n.
Trinickia
, formed after M.J. Trinick, an Australian microbiologist who was the first to isolate β‐rhizobia from
Mimosa
.

Proteobacteria / Betaproteobacteria / Burkholderiales / Burkholderiaceae / Trinickia

The genus
Trinickia
was established in 2018 grouping a discrete number of species. Members from this genus consist of seven species that have been isolated in the United States, China, Korea, and Brazil. Cells of this group of bacteria are Gram‐stain‐negative, aerobic, and non‐spore‐forming rods. Motility is species‐dependent and can optimally grow in slightly acidic pHs. The major fatty acid is C
16:0
. DNA G + C content is 62.9–64.70%. Known habitats are soil and soil where plants or trees are growing.

DNA G + C content (mol%)
:
62.98–63.50.

Type species
:

Trinickia
symbiotica

Estrada‐de los Santos et al. 2018
VP
.
Gaiellales
Authors: Albuquerque Luciana , Egas Conceição 
Published: June 2023

Abstract

Ga.i.el.la'les. N.L. fem. dim. n.
Gaiella
, type genus of the order; L. fem. pl. n. suff. –
ales
, ending to denote an order; N.L. fem. pl. n.
Gaiellales
, the
Gaiella
order.

Actinomycetota / Thermoleophilia / Gaiellales

The order
Gaiellales
is a member of the class
Thermoleophilia
. This order accommodates one family,
Gaiellaceae
, and one genus,
Gaiella
, composed of one validly published species named
Gaiella occulta
. Cells stain Gram‐negative and form rod‐shaped cells. Endospores are not observed. The members of this order are mesophilic, strictly aerobic, and chemoorganotrophic. The peptidoglycan contains
meso
‐diaminopimelic acid (
meso
‐Dpm) as diagnostic diamino acid and is of type A1γ'. The major respiratory quinone is menaquinone 7 (MK‐7). Members of the order
Gaiellales
possess internally methyl‐branched fatty acids. 16S rRNA gene sequence signature nucleotide positions 139:224 (C–G) and 722:733 (U–G) are unique to order
Gaiellales
within the class
Thermoleophilia
. The species
Gaiella occulta
was isolated from a deep aquifer.

DNA G + C content (mol%)
: 71.6 (HPLC).

DNA G + C content (%)
: 71.7 (genome).

Type genus
:
Gaiella
Albuquerque et al. 2011, VL144.
Precise Engineering of Octahedron‐Induced Subcrystalline CoMoO4 Cathode Catalyst for High‐Performance Li–Air Batteries
Authors: Zhou Huimin , Guo Liang , Zhang Runhao , Xie Lei , Qiu Yang , Zhang Guoliang , Guo Zhanhu , Kong Biao , Dang Feng 
Published: June 2023

AbstractLithium–air batteries (LABs) have attracted intense interest due to their ultrahigh energy density. However, the performance of LABs has to depend on modified electrolytes, gas selective film and Li anode protection. In this study, firstly it is reported that Mo‐O octahedron induced subcrystalline scheelite CoMoO4 catalyst achieves a high performance LABs performance based only on the high catalytic activity in air. The subcrystalline CoMoO4 catalyst obtains a specific capacity of 12 000 mAh g−1, and ultralong cycle stability over 270 cycles at 1000 mA g−1 in ambient air. This study demonstrates an ultrastable crystal structure and surface conditions of the CoMoO4 catalyst toward a corrosive environment and complex air‐involved reactions. A theoretical calculation further reveals that the polyhedral framework in the scheelite CoMoO4 can provide a highly stable catalytic surface for the OER/ORR reactions, furthermore, its repulsive nature toward H2O and CO2 can efficiently avoid side reactions and slow the corrosion of the Li anode in air. Moreover, the induced octahedron enhances the adsorption energies to O2 and LiO2, and accelerates the catalytic reactions in air. The present study provides a conceptual breakthrough to find highly active cathode catalysts for LABs.
Implicitly Represented Architected Materials for Multi‐Scale Design and High‐Resolution Additive Manufacturing
Authors: Rastegarzadeh Sina , Wang Jun , Huang Jida 
Published: June 2023

AbstractBio‐inspired structured materials have achieved unprecedented progress in realizing exceptional, effective properties. However, a rational design paradigm that enables both tailoring complex 3D architectures and manufacturing the engineered hierarchical structured materials is still missing. To bridge this gap, this study presents a holistic design‐through‐printing framework with implicitly represents cellular materials for high‐resolution structured materials design and manufacturing. Attributed to the parameterized implicit function‐based representation (FRep), the material's microstructures can be effectively controlled to tune the material properties (e.g., isotropic, orthotropic, and anisotropic) while enabling functional gradation in the multi‐scale hierarchical design. Given prescribed material properties in different applications, the proposed framework finds the optimal layout of microstructures with an adaptive cluster‐based topology optimization algorithm. The geometry frustration problem brought by the mixture of distinct microstructures is simultaneously addressed with a spatial gradation scheme in the optimization loop. Lastly, the FRep‐based architected material enables efficient geometry processing (e.g., slicing) for modern AM processes, thus facilitating the manufacturing of high‐resolution delicate designed materials. The proposed framework is scalable and adaptable to accomplish a broad spectrum of design demands in various applications.
The impact of a smartphone‐based cognitive aid on clinical performance during cardiac arrest simulations: A randomized controlled trial
Authors: Brophy Samuel L. , McCue Michael R. , Reel Riley M. , Jones Tristan D. , Dias Roger D. 
Published: June 2023

AbstractObjectivesIn‐hospital cardiac arrests are common and associated with high mortality. Smartphone applications offer quick access to algorithms and timers but often lack real‐time guidance. This study assesses the impact of the Code Blue Leader application on the performance of providers leading cardiac arrest simulations.MethodsThis open‐label randomized controlled trial included Advanced Cardiac Life Support (ACLS)–trained medical doctors (MD) and registered nurses (RN). Participants were randomized to lead the same ACLS simulation with or without the app. The primary outcome, “performance score,” was assessed by a trained rater using a validated ACLS scoring system. Secondary outcomes included percentage of critical actions performed, number of incorrect actions, and chest compression fraction (percentage of time spent performing chest compressions). A sample size of 30 participants was calculated to detect a difference of 20% at the 0.05 alpha level with 90% power.ResultsFifteen MDs and 15 RNs underwent stratified randomization. The median (interquartile range) performance score in the app group was 95.3% (93.0%–100.0%) compared to 81.4% (60.5%–88.4%) in the control group, demonstrating an effect size of r = 0.69 (Z = −3.78, r = 0.69, p = 0.0002). The percentage of critical actions performed in the app group was 100% (96.2%–100.0%) compared to 85.0% (74.1%–92.4%) in the control group. The number of incorrect actions performed in the app group was 1 (1) compared to 4 (3–5) in the control group. Chest compression fraction in the app group was 75.5% (73.0%–84.0%) compared to 75.0% (72.0%–85.0%) in the control group.ConclusionsThe Code Blue Leader smartphone app significantly improved the performance of ACLS‐trained providers in cardiac arrest simulations.
Placement and nitrogen source effects on N2O emissions for canola production in Manitoba
Authors: Tenuta Mario , Gao Xiaopeng , Tiessen Kevin H. D. , Baron Kevin , Sparling Brad 
Published: June 2023

AbstractThis study examined fertilizer nitrous oxide (N2O) emissions and canola (Brassica napus L.) grain yield for two granular urea sources (conventional and a dual urease and nitrification inhibitor [SuperU]) and three at‐planting placement methods (broadcast‐incorporated, shallow banded, and deep banded) on commercial fields in Manitoba. Nitrogen (N) rates were 100% and 70% of what was recommended based on soil test and target yield, with the 100% treatments having N2O emissions monitored. SuperU fertilizer consistently reduced N2O emissions (area‐, N‐applied‐, and yield‐based) compared to urea. Significant reductions in N2O emissions with SuperU occurred in four of six site‐years and coincided with delayed nitrification. Compared to broadcast‐incorporated, subsurface banding of conventional urea reduced N2O emissions in drier site‐years but increased emissions when rainfall was higher (especially in shallow banded urea). Across all six site‐years, shallow banding of urea resulted in significantly higher emission intensities than all other treatments. Nitrogen placement did not affect the emission reduction benefit of SuperU. N source or placement did not greatly affect canola yield within either 100% or 70% N rates. Fertilizer N recovery efficiency was also not greatly impacted by either N source or placement. The results demonstrate that dual inhibited granular urea fairly consistently reduces N2O emissions in canola production in southern Manitoba, whereas nitrogen placement had variable effects depending on growing season rainfall. However, with little agronomic benefit, the added cost of enhanced efficiency fertilizers must be overcome for widespread adoption and to achieve greenhouse gas reduction targets for the Canadian agriculture sector.
Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease
Authors: Yakoub Yara , Ashton Nicholas J. , Strikwerda‐Brown Cherie , Montoliu‐Gaya Laia , Karikari Thomas K. , Kac Przemysław R. , Gonzalez‐Ortiz Fernando , Gallego‐Rudolf Jonathan , Meyer Pierre‐François , St‐Onge Frédéric , Schöll Michael , Soucy Jean‐Paul , Breitner John C. S. , Zetterberg Henrik , Blennow Kaj , Poirier Judes , Villeneuve Sylvia ,   PREVENT‐AD Research Group
Published: June 2023

AbstractINTRODUCTIONPlasma biomarkers are altered years prior to Alzheimer's disease (AD) clinical onset.METHODSWe measured longitudinal changes in plasma amyloid‐beta (Aβ)42/40 ratio, pTau181, pTau231, neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP) in a cohort of older adults at risk of AD (n = 373 total, n = 229 with Aβ and tau positron emission tomography [PET] scans) considering genetic and demographic factors as possible modifiers of these markers’ progression.RESULTSAβ42/40 ratio concentrations decreased, while NfL and GFAP values increased over the 4‐year follow‐up. Apolipoprotein E (APOE) ε4 carriers showed faster increase in plasma pTau181 than non‐carriers. Older individuals showed a faster increase in plasma NfL, and females showed a faster increase in plasma GFAP values. In the PET subsample, individuals both Aβ‐PET and tau‐PET positive showed faster plasma pTau181 and GFAP increase compared to PET‐negative individuals.DISCUSSIONPlasma markers can track biological change over time, with plasma pTau181 and GFAP markers showing longitudinal change in individuals with preclinical AD.Highlights
Longitudinal increase of plasma pTau181 and glial fibrillary acidic protein (GFAP) can be measured in the preclinical phase of AD.
Apolipoprotein E ε4 carriers experience faster increase in plasma pTau181 over time than non‐carriers.
Female sex showed accelerated increase in plasma GFAP over time compared to males.
Aβ42/40 and pTau231 values are already abnormal at baseline in individuals with both amyloid and tau PET burden.
Hochhausstützen in Deutschland – Bestands‐ und Potenzialanalyse unter Berücksichtigung der Nachhaltigkeit
Authors: Matz Henrik , Empelmann Martin 
Published: June 2023

AbstractModerne und wirtschaftliche Konstruktionen von Hochhäusern erfordern hochtragfähige Stützen, welche zusätzlich zur sicheren Bemessung auch architektonische, technische und wirtschaftliche Anforderungen erfüllen müssen. Aus einer Sichtung und Einordnung von Stützenkonzepten an ausgeführten Hochhäusern in Deutschland in Massivbauweise über die letzten 30 Jahre kann eine Optimierungsabfolge von „Beton“ über „Bewehrung“ zur „Fertigung“ festgestellt werden. Die Auswirkungen der Optimierungsstrategien werden in einer qualitativen Potenzialanalyse unter den Aspekten „Tragfähigkeit, Robustheit, Bauzeit, Kosten und Nachhaltigkeit“ anschaulich dargestellt und zeigen einen deutlichen Trend zu Fertigteilstützen aus hochfestem Beton mit hochfester Bewehrung und hohen Bewehrungsgraden (3H‐Stützen). Aus weiter zunehmenden Anforderungen an die Nachhaltigkeit, aber auch zur Schließung von Regelungslücken bei modernen Hochhausstützen in den Normen ergeben sich aktuelle Fragestellungen. Hierzu werden Forschungsansätze und Lösungsvorschläge vorgestellt.
Discrimination of Polygonati Rhizoma Species: An Investigation Utilizing High‐Performance Liquid Chromatography Fingerprints and Chemometrics
Authors: Zhou Kexin , Liu Meiqi , Gao Jie , Liu Yi , Ren Xiaoliang , Sun Lili , Liu Yanan 
Published: June 2023

AbstractPolygonati Rhizoma has been a famous traditional Chinese medicine (TCM) for two thousand years. It is increasingly being used not just as a traditional herbal medicine but also as a popular functional food. In this study, qualitative and quantitative analysis of PR from three different origins were initially performed using chemical fingerprint and chemometrics methods. Hierarchical cluster analysis (HCA) and Principal component analysis (PCA) were used to classify 60 PR samples from three different origins. The results revealed that the PR samples fell into three clusters related to the origins. In addition, pairwise comparison of varying PR and obtaining chemical markers between different species through the establishment of partial least squares discriminant analysis. Finally, chemical markers 9,13 and 17 were identified by LC/MS as disporopsin, 5,7‐dihydroxy‐3‐(4′‐hydroxybenzyl)‐6,8‐dimethylchroman‐4‐one and (3R)‐5,7‐dihydroxy‐3‐(4′‐hydroxybenzyl)‐6‐methylchroman‐4‐one or isomer, respectively. In conclusion, these methods can be applied to identify and distinguish the quality of PR with other original plants and provide novel ideas for evaluating herbal products used in TCM.
Patient with lupus anticoagulant caused aPTT prolongation corrected with prednisolone treatment and later anticoagulation treatment due to chronic atrial fibrillation
Authors: Frydrysiak Marlena , Pachniak Paulina , Krysicka Anna , Moczulski Dariusz 
Published: June 2023

Key Clinical MessageLupus anticoagulant caused aPTT prolongation in rare case can cause bleeding tendency especially when combined with other hemostasis abnormalities. In such cases, aPTT value can be corrected by immunosuppressants within several days of treatment. When anticoagulation therapy is needed vitamin K antagonist are a good option for the initial treatment.AbstractLupus anticoagulant antibodies despite causing aPTT prolongation are commonly associated with increased risk of thrombosis. We present a rare case of patient when these autoantibodies resulted in dramatic aPTT prolongation and combined with associated thrombocytopenia resulted in minor bleeding events. In presented case treatment with oral steroids resulted in aPTT values correction followed by resolution of bleeding tendency within several days. Later, the patient developed chronic atrial fibrillation and was started on anticoagulation treatment initially with vitamin K antagonist without bleeding complications during follow‐up period. Corresponding changes in patient's aPTT time in a course of whole treatment is presented.