bluuebunny/crossref_metadata_2025_split huggingface dataset:
Empathy and Self-Compassion Mediate the Relationships between Parental Attachment, Prosocial Behavior, and Antisocial Behavior among Adolescents after the Jiuzhaigou Earthquake
Authors: Liu Aiyi , Wang Wenchao , Wu Xinchun , Xu Boya 
Published: March 2023

Abstract

Objective
This study examined the mediating roles of empathy and self-compassion in the relationship between parental attachment, prosocial behavior, and antisocial behavior among Chinese adolescents after the Jiuzhaigou earthquake.
Methods
A total of 411 adolescents (M = 14.73, SD = 0.91) were assessed 16 months after the Jiuzhaigou earthquake using self-report questionnaires of trauma exposure, parental attachment, empathy, self-compassion, prosocial behavior, and antisocial behavior.
Results
The parental attachment had a positive effect on prosocial behavior via empathy and positive self-compassion, as well as via an indirect path from empathy to positive self-compassion. Parental attachment had a negative effect on antisocial behavior via empathy and negative self-compassion, and had an indirect path from empathy to negative self-compassion.
Conclusions
These findings indicate that enhancing parental attachment may promote prosocial behavior and reduce antisocial behavior of post-earthquake adolescents. Empathy and self-compassion play significant mediating roles between parental attachment, prosocial behavior, and antisocial behavior.
Energy losses in photovoltaic generators due to the wind patterns
Authors: Rossa Carlos 
Published: March 2023

Abstract
Wind patterns play a key role in the energy production of the photovoltaic power plant. The heat flux from the photovoltaic generator surface to the air varies while the air flux develops from a laminar to a turbulent regime. The decrease of the heat transfer coefficient with the air flux development makes the temperature in the turbulent zone remain high. This increases the temperature dispersion inside the whole photovoltaic generator up to 14 °C1 , slightly increasing the mismatch losses2 . However, the impact of wind patterns on big PV generators remains unknown. It is demonstrated that the wind speed increase is responsible for the mismatch losses increase. Benefits of photovoltaic cooling, usually composed by a single module3–9 , are commonly assumed to be the same in photovoltaic generators. Contrarily to this common belief, the consequent overall thermal behaviour due to the wind speed affects negatively energy production. Considering both the long-term energy estimations and lifespan of a photovoltaic power plant, these experimental results suggest that the wind patterns cannot be neglected, especially in the next years due to the climatic change.
ShIVA – A user-friendly and interactive interface giving biologists control over their single-cell RNA- seq data
Authors: Aussel Rudy , Asif Muhammad , Chenag Sabrina , Jaeger Sébastien , Milpied Pierre , Spinelli Lionel 
Published: March 2023

Abstract
Single-cell technologies have revolutionised biological research and applications. As they continue to evolve with multi-omics and spatial resolution, analysing single-cell datasets is becoming increasingly complex. For biologists lacking expert data analysis resources, the problem is even more crucial, even for the simplest single-cell transcriptomics datasets.
We propose ShIVA, an interface for the analysis of single-cell RNA-seq and CITE-seq data specifically dedicated to biologists. Intuitive, iterative and documented by video tutorials, ShIVA allows biologists to follow a robust and reproducible analysis process, mostly based on the Seurat v4 R package, to fully explore and quantify their dataset, to produce useful figures and tables and to export their work to allow more complex analyses performed by experts.
Finite element analysis of the plantar support for the medial longitudinal arch with flexible flatfoot
Authors: Long Xiao , Yuan Cheng-jie , Xu Jian , Liu Tao , Zhang Yi-jun 
Published: March 2023

Abstract
Background
The present study is to explore the appropriate plantar support force for its effect on improving the collapse of the medial longitudinal arch with flexible flatfoot.
Methods
A finite element model with the plantar fascia attenuation was constructed simulating as flexible flatfoot. The appropriate plantar support force was evaluated. The equivalent stress of the articular surface of the joints in the medial longitudinal arch and the maximum principal stress of the ligaments around the ankle were obtained.
Results
The height fall is smaller when applying 15% of body-weight-bearing force as the plantar support for the medial longitudinal arch compared with 10% of the body-weight-bearing while 20% of body-weight-bearing force is over plantar support. The equivalent stress on the articular surface of each joint is smallest when applying 15% of body-weight-bearing force compared with 10% or 20% of the body-weight-bearing force. The maximum principal stress of the anterior talofibular ligament is decreased while other ligaments increased when the plantar fascia attenuation under loading. The maximum principal stress of the tibiocalcaneal ligament and the posterior tibiotalar ligament are decreasing while other ligaments increased with the force increasing gradually.
Conclusions
Applying 15% of body-weight-bearing to the sole of the foot can restore the height fall of the medial longitudinal arch, and relieve the equivalent articular stress of the talonavicular joint and the talocalcaneal joint as well as the tension stress of the tibiocalcaneal ligament and the posterior tibiotalar ligament.
Committing to Reproducibility and Explainability]{Committing to Reproducibility and Explainability: Version Control as Research Journal
Authors: Huskey Samuel 
Published: March 2023

Abstract
Traditional critical editions in print offer a model for creating a culture of reproducible and explainable research in Digital Humanities. In addition to explaining their editorial methods and practices in a preface, editors provide a critical apparatus to allow readers to evaluate the evidence and decide for themselves whether the editor's judgment is sound. This paper will argue for viewing distributed, version-controlled data repositories (e.g., Git) in the same way, to empower users to follow the choices and methods of DH researchers and to reproduce their work. Using examples from a current project, this paper will propose some guidelines for using Git to promote reproducibility and explainability in the publication of DH research of all kinds.
Effectiveness of Repetitive Transcranial Magnetic Stimulation Combined with Transspinal Electrical Stimulation on Corticospinal Excitability for Individuals with Incomplete Spinal Cord Injury: A Pilot Study
Authors: Lin Bor-Shing , Zhang Zhao , Peng Chih-Wei , Chen Shih-Hsuan , Chan Wing P , Lai Chien-Hung 
Published: March 2023

Abstract
Repetitive Transcranial Magnetic Stimulation (rTMS) and transspinal electrical stimulation (tsES) have been proposed as a novel neurostimulation modality for individuals with incomplete spinal cord injury (iSCI). In this study, we integrated magnetic and electrical stimulators to provide neuromodulation therapy to individuals with iSCI. We then designed a clinical trial comprising an 8-week treatment period and a 4-week treatment-free observation period. Assessments of cortical excitability, clinical features, inertial measurement unit and surface electromyography were conducted every 4 weeks. Twelve individuals with iSCI were recruited and randomly divided into a combined therapy group, a magnetic stimulation group, an electrical stimulation group, or a sham stimulation group. The magnetic and electric stimulations provided in this study were intermittent theta-burst stimulation (iTBS) and 2.5-mA direct current (DC) stimulation, respectively. According to the results, combined therapy, which involves iTBS and transspinal DC stimulation (tsDCS), was more effective than was iTBS alone or tsDCS alone in terms of increasing corticospinal excitability. In addition, the effectiveness of 8-week combined therapy in increasing corticospinal excitability faded 4 weeks after the cessation of treatment. Although promising, the results of this study must be validated by studies with longer interventions and larger sample sizes.
Exploring the effectiveness of Chinese herbal medicine as an "iron blade" to get rid of a "hidden murderer" hypertension
Authors: Meng Yiming , Sun Jing , Zhang Guirong 
Published: March 2023

Abstract
The world faces the dual pressures of an aging population and the prevalence of metabolic risk factors. The morbidity and mortality of cardiovascular disease (CVD) continue to increase, becoming one of the important causes of death in the population. Chinese herbal medicine can also change abnormal metabolism while lowering blood pressure. It has an extraordinary curative impact and promises to prevent and treat hypertension. Iron-dependent lipid reactive oxygen species buildup and polyunsaturated fatty acid consumption in the plasma membrane, involving three processes—lipid metabolism, amino acid metabolism, and iron metabolism—are always present when ferroptosis occurs. It is crucial for the pathophysiology of CVD. Therefore, finding Chinese herbal medicine to treat ferroptosis, screen out the active ingredients, and explore the therapeutic targets related to ferroptosis in hypertension is an urgent problem. In this study, network pharmacology was used to find that Stigmsterol, sitosterol, kaempferol, beta-sitosterol, and quercetin were the main active constituents of Toosendan Fructus, Jujubae Fructus, Flos Puerariae Lobatae, Peucedani Radix, Crataegi Folium, and Potentiliae. To reach the goal of treating hypertension, these active components target CAV1, IL6, TGFB1, HMOX1, TP53, IL1B, HIF1A, GJA1, EGFR, and NEDD4L to control ferroptosis. The current work provides a more in-depth understanding of Chinese herbal medicine used to treat hypertension through ferroptosis for future drug optimization.
Friction Angles of Sands – An Appraisal
Authors: K Prakash , A Sridharan , N Manoj , . Manoj 
Published: March 2023

Abstract
River sand is a naturally occurring conventional construction material, which has good frictional properties. Due to a steep rise in the construction activities all over the world, natural sand resources are getting depleted. This has favored / forced the construction industry in general and geotechnical engineering practice in particular to go for M-sands. This necessitates a proper understanding of the frictional characteristics of M – sands. In this technical note, the results from a comparative study of the friction angles of river sand and M-sand with reference to the effect of grain size, grain angularity, dry density and gradation are reported. It is shown that M-sand exhibits higher friction angles than river sand at minimum density levels and river sand exhibits higher friction angles than M-sand at maximum density levels, on average, irrespective of grain size. It is also shown that poorly graded M-sands exhibit higher friction angles than well graded M-sands at minimum density levels, whereas well graded river sands have higher friction angles than poorly graded river sands irrespective of density levels.
Reciprocal influence of soil, phyllosphere and aphid microbiomes
Authors: Wolfgang Adrian , Tack Ayco J. M. , Berg Gabriele , Abdelfattah Ahmed 
Published: March 2023

Abstract
Background

The effect of soil on the plant microbiome is well-studied. However, less is known about the impact of soil microbiome in multitrophic systems. Here we examined the effect of soil on plant and aphid microbiomes, and the reciprocal effect of aphid herbivory on the plant and soil microbiomes. We designed microcosms, which separate below and aboveground compartments, to grow oak seedlings with and without aphid herbivory in soils with three different microbiomes. We used amplicon sequencing and qPCR to characterize the bacterial and fungal communities in soils, phyllospheres, and aphids.

Results

Soil microbiomes significantly affected the microbial communities of phyllospheres and, to a lesser extent, aphid microbiome, indicating plant-mediated assembly processes from soil to aphids via the plant endosphere. While aphid herbivory significantly decreased microbial diversity in phyllospheres independent of soil microbiomes, the effect of aphid herbivory on the community composition in soil varied among the three soils.

Conclusions

This study provides experimental evidence for reciprocal influence of soil, plant and aphid microbiomes, with potential for the development of new microbiome-based pest management strategies.
A graphitic nano-onion/molybdenum disulfide nanosheet composite as a platform for HPV-associated cancer-detecting DNA biosensors
Authors: Kim Youngjun , Kang Eunah 
Published: March 2023

Abstract
An electrochemical DNA sensor that can detect human papillomavirus (HPV)-16 and HPV-18 for the early diagnosis of cervical cancer was developed by using a graphitic nano-onion/molybdenum disulfide (MoS2) nanosheet composite. The electrode surface for probing DNA chemisorption was prepared via chemical conjugation between acyl bonds on the surfaces of functionalized nanoonions and the amine groups on functionalized MoS2 nanosheets. The cyclic voltammetry profile of an 1:1 nanoonion/MoS2 nanosheet composite electrode had an improved rectangular shape compared to that of an MoS2 nanosheet elecrode, thereby indicating the amorphous nature of the nano-onions with sp2 distancing curved carbon layers that provide enhanced electronic conductivity, compared to MoS2 nanosheet only. The nanoonion/MoS2 sensor for the DNA detection of HPV-16 and HPV-18, respectively, was measured at high sensitivity through differential pulse voltammetry (DPV) in the presence of methylene blue (MB) as a redox indicator. The DPV current peak was lowered after probe DNA chemisorption and target DNA hybridization because the hybridized DNA induced less effective MB electrostatic intercalation due to it being double-stranded, resulting in a lower oxidation peak. The nanoonion/MoS2 nanosheet composite electrodes attained higher current peaks than the MoS2 nanosheet electrode, thereby indicating a greater change in the differential peak probably because the nanoonions enhanced conductive electron transfer. Notably, both of the target DNAs produced from HPV-18 and HPV-16 Siha and Hela cancer cell lines were effectively detected with high specificity. The conductivity of MoS2 improved by complexation with nano-onions provides a suitable platform for electrochemical biosensors for the early diagnosis of many ailments in humans.
Preoperative BChE serves as prognostic marker in patients with resectable AEG after neoadjuvant chemotherapy
Authors: Gensthaler Lisa , Jomrich Gerd , Brugger Jonas , Kollmann Dagmar , Paireder Matthias , Bologheanu Milena , Riegler Franz M. , Asari Reza , Schoppmann Sebastian F. 
Published: March 2023

Abstract
Background: Diminished systemic serum butyrylcholinesterase (BChE), a biomarker for chronic inflammation, cachexia, and advanced tumor stage, has shown to play a prognostic role in various malignancies. Aim of this study was to investigate the prognostic value of pretherapeutic BChE levels in patients with resectable adenocarcinoma of the gastroesophageal junction (AEG), treated with or without neoadjuvant therapy.
Methods: Data of a consecutive series of patients with resectable AEG at the Department for General Surgery, Medical University of Vienna were analyzed. Preoperative serum BChE levels were correlated to clinic-pathological parameters as well as treatment response. Prognostic impact of serum BChE levels on disease free (DFS) and overall survival (OS) were evaluated by univariate and multivariate cox regression analysis, Kaplan-Meier curves used for illustration.
Results: 319 patients were included in this study, with an overall mean (Standard deviation, SD) pretreatment serum BChE level of 6.22 (+/-1.91) IU/l. In univariate models, diminished preoperative serum BChE levels were significantly associated with shorter overall (OS, p<0.003) and disease-free survival (DFS, p<0.001) in patients who received neoadjuvant treatment and/or primary resection. In multivariated analysis, decreased BChE was significantly associated with shorter DFS (HR: 0.92, 95%-CI: 0.84-1.00, p 0.049) and OS (HR: 0.92, 95%-CI: 0.85-1.00, p<0.49) in patients receiving neoadjuvant therapy. Backward regression identified the interaction between preoperative BChE and neoadjuvant chemotherapy as an predictive factor for DFS and OS.
Conclusion: Serum BChE serves as strong, independent, and cost-effective prognostic biomarker for worse outcome in patients with resectable AEG who had received neoadjuvant chemotherapy.
Synopsis
Diminished systemic serum Butyrylcholinesterase (BChE) serves as a strong and independent prognostic biomarker for shortened DFS and OS in patients with resectable adenocarcinoma of the gastroesophageal junction (AEG) after preoperative neoadjuvant treatment. BChE levels could be of use in clinical practice when measured prior to surgery, especially in those patients who had received neoadjuvant chemotherapy.
Using Teaching Interaction Procedure to Increase Empathetic Responding During Cross-racial Behavior Analytic Supervisory Relationships
Authors: Robinson Sapphire U. , Parks Natalie , Lewis Heather L. , Rigdon Charda'e P. 
Published: March 2023

Abstract
As graduate student's racial/ethnic identities continue to diversify among individuals pursuing applied behavior analysis, there is an increased risk for marginalization to occur during supervision. To promote successful supervisor-supervisee relationships, supervising behavior analysts need to acquire culturally responsive practices such as empathetic responding and partake in continuous education to shape their supervising repertoire. This will expand their ability to provide quality support for supervisees belonging to various identity groups. The teaching interaction procedure is a training tool that can be used to teach culturally responsive practices to supervising behavior analysts. It is an evidenced- based tool that has been used to teach social skills to children and adults. This training tool procedural components consist of labeling the social skill, providing rationale for that social skill, describing the steps involved in the social skill, modeling examples and non-examples of the social skill, and providing feedback throughout the process. The purpose of this study was to evaluate the teaching interaction procedure effectiveness as a training tool to teach empathetic responding skills to three supervising behavior analysts within cross-racial dyads in a web-based training format. The results of a multiple-baseline design will show the teaching interaction procedure was effective at training all 3 supervisors empathetic responding in a contrived setting and suggests this had a positive impact on the perceived level of satisfaction among their supervisees.
Bilateral high-riding jugular bulb associated with a jugular diverticulum and dehiscence of the mastoid cells and Trautmann’s triangle
Authors: Alnafie Mohammed Assaad 
Published: March 2023

Abstract
A 30-year-old man underwent a high-resolution computed tomography of both temporal bones as part of the assessment of horizontal rotatory vertigo, pulsatile tinnitus, and mild hearing loss. First, we observed a bilateral high-riding jugular bulb with a right jugular diverticulum. Then, the right jugular bulb and the diverticulum were dehiscent in mastoid cells and Trautmann’s triangle. This case report illustrates a new presentation of the dehiscent high-riding jugular bulb and jugular diverticulum. We believe it deserves to be shared.
Physicochemical and Pharmacokinetic Properties’ Screening of Selected Cardiovascular Agents: an in-silico Approach
Authors: Inamdar Aparna , Pote Shweta , Sawant Suraj , Salve Preeti S , Suryawanshi Shailendra S. , Palled Mahesh 
Published: March 2023

Abstract
Cardiovascular (CVS) drugs are medications whose primary effects are experienced by the heart and blood vessels to treat cardiovascular disorders such as coronary artery disease, arrhythmias, high blood-pressure, heart failure and stroke. Evaluation of drug-likeness is a qualitative research approach in drug design that examines the drug-like properties of any chemical compound used as a lead in terms of factors such as oral bioavailability. These ADME parameters can be used widely in drug discovery to optimize the properties needed to convert lead candidates into safe and effective drugs for human use. An approach to estimate the passive gastrointestinal (GI) absorption and blood-brain barrier (BBB) access of drugs is the BOILED-Egg model from Swiss-ADME. In the current study, we virtually screened fifty-five bioactive CVS agents, which twenty-three were newly marketed agents and thirty-two were conventional agents. PubChem database for canonical smile collection, Molsoft server for physicochemical properties and drug-likeness screening, Schrodinger's software for ADME parameters, Microsoft Excel software for Heat-Map analysis, Swiss-ADME database for construction of BOILED-Egg model were utilized. The study results revealed that out of fifty-five screened bioactive drugs, forty-six drugs obeyed Lipinski's rule of five (RO5) and forty-five drugs obeyed Jorgensen's rule of three (RO3), were within recommended ranges of physicochemical and pharmacokinetic properties. Few of the compounds found in the Egg-yolk and Egg-white were predicted to pass the BBB and GI, respectively. It can be concluded that maximum of the screened bioactive drugs are proved to be potent drug candidates with good membrane permeability and oral bioavailability.