bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanical Insufflation-Exsufflation to promote extubation success in critically ill adults on intensive care: Protocol for a randomised controlled feasibility trial
Authors: Swingwood Ema L , Voss Sarah , Tume Lyvonne , Bewley Jeremy , Turner Nicholas , Ntoumenopoulos George , Rose Louise , Cramp Fiona 
Published: January 2023

Abstract
Background: Extubation failure, defined as reintubation within 48 hours is associated with increased intensive care unit (ICU) length of stay and higher mortality risk. One cause of extubation failure is secretion retention, resulting from an inability to cough effectively. Mechanical Insufflation-Exsufflation (MI-E) simulates a cough aiding secretion clearance. However, MI-E is not routinely used in the ICU setting for invasively ventilated patients. This study aims to determine the feasibility and acceptability of a randomised controlled trial (RCT) examining MI-E use to promote extubation success in intubated, ventilated adults.
Methods: Single centre, feasibility RCT with semi-structured interviews, economic scoping, and an exploratory physiology study.
The feasibility RCT (n=50) will compare standard care to a MI-E protocol including a minimum of two MI-E sessions via the endotracheal tube prior to extubation. Post-extubation, MI-E will be delivered via facemask or mouthpiece up to two times/day for 48 hours. MI-E settings will be individualised based on patient tolerance, chest expansion and secretion clearance. All patients will receive standard care in relation to mechanical ventilation, weaning, rehabilitation, physiotherapy techniques such as positioning, manual airway clearance techniques, manual/ventilator hyperinflation, endotracheal suctioning and nebulisation. Clinical data collection will occur before, on completion and 5 minutes after all physiotherapy sessions (intervention and control arms). Resource use will be calculated for each 24 hour period. Analyses will be descriptive and address feasibility outcomes.
We will conduct semi-structured online interviews informed by the Theoretical Framework of Acceptability (TFA) with patients, clinicians and family members, exploring the acceptability of the MI-E intervention and study processes.
Interview data will be analysed using reflexive thematic analysis based on TFA domains through first level coding.
The embedded physiology study will use Electrical Impedance Tomography and Lung Ultrasound to explore lung recruitment and de-recruitment during MI-E in a subset of 5-10 patients.
Discussion: This study will examine the feasibility and acceptability of a RCT protocol of MI-E to promote extubation success. Study findings will inform further design modification and conduct of a future adequately powered trial. Furthermore, the study will contribute and advance the understanding of MI-E use in critically ill intubated adults.
Trial Registration: ISRCTN 24603037; IRAS 303674.
The effect of photobiomodulation on bone mineral density in individuals with complete spinal cord injuries with osteoporosis
Authors: Mohammadzadeh Esmaeil , Amiri Aref Hosseinian , Fekrazad Reza , Leitgeb Rainer A. , Mayr Winfried , Ezzati Kamran 
Published: January 2023

Abstract
Study Design: A quasi-experimental (matched-pair-design)study. Patients received local photobiomodulation(LPBM) on one side of their body and the control group was assigned to other side, at the same locations.
Objectives: To evaluate the LPBM effects on bone-mineral-density(BMD), in complete spinal-cord-injury(C.SCI) patients with osteoporosis(OP) by follow-up dual-energy X-ray-absorptiometry(DEXA).
Setting: The clinic of Mazandaran University of Medical Science, Sari, Iran
Methods: A total of 23 locations consisting of three-therapeutic-locations(TTLs): Forearm-MID, proximal-femur(PFe), proximal-tibia(PTib), in eight patients (except, forearm-MID with seven) were included LPBM treatment for 8 weeks. BMD were measured using DEXA in both side, at Week-8 of LPBM and at Week-15 for follow-up. Different doses were adjusted depending on the anatomical distance between the skin surface and bone depth as determined by sonography to deliver the optimal isodose at each depth for bone. This study used data from TTLs: Forearm-MID, PFe and PTib to analyze as subgroup effects. We also assessed serum 25-OH-Vitamin-D(Total) during the baseline and Week-8 of treatment
Results: BMD, statistically increased at Week-8 of LPBM and at Week-15 for follow-up compared with control group. Subgroup analysis showed, a statistically significant effect of LPBM on BMD, in both PFe and forearm MID, compared with their control, but not at the PTib. A statistically significant, increase in serum 25(OH)-Vitamin-D was found between Week-8 of LPBM treatment and baseline.
Conclusion: LPBM with an 830nm laser provided an appropriate dose calculation considering the depth is effective in increasing BMD in C.SCI patient with OP and can lead to a favorable effect on vitamin-D metabolism.
Mobility Management with Dynamic Forwarding in Smart Grid Communication
Authors: Ma Tianxiang , Duan Xin , Zeng Siming , Fan Hui , Luo Peng , Jia Boyan , Mao Yachun , Liu Deliang 
Published: January 2023

Abstract
Smart Grid, as a promising future architecture of Power Grid, its server mobility management is one of the important research contents in communication. Once the server moves, the routing table of some nodes will be invalid. As a result, the mobile server cannot be routed, which interrupts the requests of users and reduces the quality of network service. To solve the above problems, a mobility support mechanism based on the dynamic forwarding is pro-posed to ensure the stability of network. This mechanism updates the for-warding state on the router content plane by dynamically tracking the server’s location to reduce the unreachability of content during server movement. The simulation results show that DoM-FP can fully support server mobility. In the speed range of 0–30 m/s, the average packet loss rate caused by the mobile server is 8.1%, and the average retrieval delay is stable at 287.3ms. Addition-ally, the average additional consumption required to support server mobility is 0.35 packet/s.
Analysis of public emotion on flood disasters in southern China in 2020 based on social media data
Authors: Ma Mingjun , Gao Qiang , Xiao Zishuang , Hou Xingshuai , Hu Beibei , Jia Lifei , Song Wenfang 
Published: January 2023

Abstract
The exploding popularity of social networks, provides a new opportunity to study disasters and public emotion. Among the social networks, Weibo is one of the largest microblogging services in China. Taking Guangdong and Guangxi in the south of China as a case, Web Scraper was used to obtain Weibo texts related to floods in 2020. The spatial distribution of floods was analyzed using Kernel Density Estimation. Public emotion was analyzed using Natural Language Processing (NLP) tools. The association between floods and public emotion was explored through correlation analysis methods. The results indicated that: (1) Weibo texts could be utilized as an eﬀective data to identify urban waterlogging risk in Guangdong and Guangxi. (2) More floods occurred in the southeast than in the central and northwest, and more in the south than in the north in Guangdong and Guangxi. The coastal cities and provincial capitals were severely affected. (3) The public emotion was mainly negative and varied significantly over time, generally showing stronger negative emotion during periods of heavy precipitation. (4) There was a strong correlation between public emotion and floods in spatial-temporal variation. The degree of negative public emotion was significantly influenced by the number of waterlogging points. The presented results serve as the pre-liminary data for future planning and designing of emergency management.
Human-Robot Relationship: long-term effects on disclosure, perception and well-being
Authors: Laban Guy , Kappas Arvid , Morrison Val , Cross Emily S. 
Published: January 2023

Abstract
Since interactions with social robots are novel and exciting for many people, one concern is the extent to which people’s behavioural and emotional engagement with robots might develop from initial interactions with a robot, when a robot’s novelty is especially salient, and sustained over time. This challenge is particularly noticeable in interactions designed to support people’s wellbeing, with limited evidence for how social robots can support people’s emotional health over time. Accordingly, this research is aimed at studying how long-term repeated interactions with a social robot affect people’s self-disclosure behaviour toward the robot, perceptions of the robot, and how it affected factors related to well-being. We conducted a mediated long-term online experiment with participants conversing with the social robot Pepper 10 times over 5 weeks. We found that people self-disclose increasingly more to a social robot over time, and found the robot to be more social and competent over time. Participants’ moods got better after talking to the robot and across sessions, they found the robot’s responses to be more comforting over time, and they also reported feeling less lonely over time. Finally, our results stress that when the discussion theme was supposedly more emotional, participants felt lonelier and stressed. These results set the stage for addressing social robots as conversational partners and provide crucial evidence for their potential introduction as interventions supporting people’s emotional health through encouraging self-disclosure.
A patient with extensive meningeal calcification due to pseudohypoparathyroidism: A case report
Authors: Daoud Mahmoud , Elamin Abubakr , Rizgalla Ahmed , Hassan Abdallah 
Published: January 2023

Abstract
Background: This case emphasizes the adulthood onset of PHP with the association of new pattern of brain calcification which is exclusively falx cerebri and supratentorial.
Case presentation: A 35-year-old man with 17-year history of epilepsy on Carbamazepine, refered from neurosurgical department where was diagnosed with hydrocephalus complicated by secondary severe optic atrophy and underwent Ventriculo-Peritoneal shunt. Imaging revealed Falx Cerebri, Supratentorial calcification , biochemical tests showed hypocalcemia, hyperphosphatemia and elevated parathyroid hormone. Patient was given Vitamin D and Calcium in order to improve the outcome.
Conclusion: Although PHP being a rare possibility especially in adult , it has to be considered in incidental meningeal calcification,and to be picked up early before complications.
Grow Newtonian rigid inertia into parameter repetitiveness memory equivalent bio-inertia by degenerating eigenstates on a surface tension region to define quantum growth gravity for turnover selection immunity
Authors: Lai Yi Yu 
Published: January 2023

Abstract
Note: Please see pdf for full abstract with equations.
Inversion energy is parameter-against-gravity-internal-fluctuations, the non-simultaneousness tension among turnover fluctuations is quantizing time. Modified Newtonian Laws are, first: 𝑑/𝑑𝑥 cosx =−𝑠𝑖𝑛𝑥, 𝑑/𝑑𝑥 sinx = 𝑐𝑜𝑠𝑥; second: 𝐹⃗=𝑚∙𝑎⃗+|𝑚𝑔⃗∫𝑡𝑔𝜃⋅𝑑𝜃 ⟩↿⇂ third: Wavelength =2/𝑛 L, frequency = n𝑓0. Bio-systems are topological spaces that can process input objects into inversion energy for entropy-control by repetitiveness memory, the capability of equivalent procured inversion energy with memorized trigonometric repetitiveness is bio-inertia. Schrödinger equation has only quantized energy thus inducing quantum collapse, we then write down equation 𝑯̂𝜓=𝑬𝜓 + Σn|cos(1/𝑛 𝑥)⟩ to grow eigenstates on certain surface tension regions to define quantum growth gravity for lifespan. Originating from quantum gravitational turnover (resistance) tension between Planck regions and surface tension regions, bio quantum grows in vivo cross folded-surface tension region flow. Life relies on trigonometric negentropy procured from elastic entropy generation ground condensates and physically inherit by quantum growth turnover immunity that inversely regenerates by yolk sac homing. Long COVID niches grow from the turnover tension is also unveiled.
Self-Care Behaviors in Preventing COVID-19 based on the Health Belief Model in Yazd during 2019
Authors: Rahighee fateme , Asadi Leila , moshirenia Fateme , Namayandeh Seyedeh Mahdieh , hardani Mahdieh , Khorsandi Behjat 
Published: January 2023

Abstract
Objective: Identification of the self-care behaviors and their barriers in the COVID-19 pandemic can help health policymakers design appropriate and practical plans. The purpose of this study was to investigate effective self-care behaviors in preventing COVID-19 based on the health belief model (HBM) in Yazd in 2019.
Materials and Methods: The present cross-sectional descriptive study was conducted using the convenience sampling method. The research data were collected via a researcher-made questionnaire based on the HBM. Followed by confirming its validity and reliability, the questionnaire was distributed on social networks and 232 questionnaires were collected and analyzed by running SPSS20
Results: The participants’ mean age was 35.5 ± 11.9 years and the majority of them (49%) were at a moderate level of economic status. No significant correlation was observed between the participants’ mean scores of HBM constructs and their age, gender, and education level (pv≥0.05). The HBM constructs could significantly predict preventive behaviors of COVID-19 and accounted for 29.6% of their changes (Adjusted R2= 0.296, F = 18.85, p ≤ 0.000). Among the HBM constructs, the perceived barriers construct was the best predictor of the disease (B = 0.268, p ≤ 0.000)
Conclusion: As an expectancy-value theory, HBM addresses the desire to avoid diseases and the belief that health-related measures can prevent illnesses. Based on the findings, the perceived susceptibility, perceived benefits, and perceived severity of the participants’ self-care behaviors were at favorable levels but their perceived barriers and self-efficacy in terms of the self-care behaviors related to COVID-19 were not in a favorable status. To meet this problem, planning educational interventions is recommended to improve self-care behaviors.
Biological Effects of Negative Air Ions on Human Health and Integrated Multi-omics to Identify Biomarkers: A literature review
Authors: Xiao Sha , Wei Tianjing , Petersen Jindong Ding , Zhou Jing , Lu Xiaobo 
Published: January 2023

Abstract
Environmental pollution seriously affects human health. As one of the factors to evaluate air quality, negative air ions (NAIs) are widely considered a marker by scholars due to their unique biological function since their discovery at the end of the 19th century. NAIs are produced from alterations in the atmosphere and weather phenomena by natural radioactivity or combustion processes and can also be generated by air ionizers sold commercially. Therefore, much interest has been given to the possible effects of NAIs on human health and well-being. Research has shown that exposure to NAIs may benefit our health, such as cardiovascular system, respiratory system, and mood, but the conclusions are inconsistent. This study summarizes and prospects the research progress of domestic and foreign scholars on the generation, temporal, and spatial dynamic patterns of NAIs concentration and their relationship with human health from the overview aspects of NAIs, and biological effects of NAIs. Subsequently, we focused on the biological mechanism of NAIs based on omics as these are relatively new methods with some advantages in studying the action of NAIs.
Assessment of Landslide susceptibility and risk implication to road network in Mt Elgon, Uganda
Authors: Nakileza Bob Roga , Mugagga Frank , Musali Paul , Nedala Shafiq 
Published: January 2023

Abstract

Globally landslides occurrence is reportedly frequent particularly in the mountainous regions causing both direct and indirect effects to various sectors including the road transport. Existing literature reveals limited assessment of road vulnerability to landslides in the mountain regions in Africa. The objective of this study was to investigate the risk to different segments of the road network in the Mt Elgon region. A Fuzzy logic model was used to assess and map the landslide susceptibility of the study area. A total of 478 landslide sites were used in the model development. Ten conditional factors were applied for generating the dataset for training and validation of the model. The results reveal that mid to high altitude steep and rugged areas are more susceptible to landslides. The model performance was good as revealed by high Area Under the Curve (AUC) of 83% and thus can be relied upon in landslide susceptibility mapping. The hotspot segments, which are high risk sections of the road network need to be prioritized for monitoring so as to initiate and strength existing risk mitigation strategies.
Preparation of environmental probiotic factor γ-polyglutamic acid via microbial fermentation using Baijiu brewing steamer bottom water as a basic substrate
Authors: Wang Fengqing , Yang Can , Chen Yanmei , Li Mengxue 
Published: January 2023

Abstract
1) Purpose: Steamer bottom water is the main component of wastewater in the Baijiu industry.
2) Methods: In this study, γ-PGA was synthesized through fermentation using steamer bottom water as a substrate to address wastewater treatment problems and costs in Baijiu enterprises. A new, cheap raw material and process of γ-PGA production were developed.
3) Results: The γ-PGA yield was 48.29 g/L, which was 1.98 times higher than that before optimization. We detected 12 volatile substances in the fermentation broth; acetic acid, 2,3-butanedione, 2-methyl-butanoic acid, and acetoin were recognized as plant probiotics. The N, P, K, and total nutrient (sum of N, P, and K) contents were 4,100, 3,405, 885, and 8,390 mg/L, respectively; the number of viable Bacillus subtilis was 4.5×107 CFU/mL.
4) Conclusion: Therefore, steamer bottom water of Baijiu brewing can completely replace water as a fermentation medium solvent to produce γ-PGA. Moreover, the fermentation broth is a potential functional organic fertilizer.
Allelic and genotypic frequencies of SNP related to beef and carcass quality in Romosinuano cattle in Mexico
Authors: Martínez-Rocha Ricardo Emmanuel , Ramírez-Valverde Rodolfo , Núñez-Domínguez Rafael , García-Muñiz José G. , Parra-Bracamonte Gaspar M. , Domínguez-Viveros Joel 
Published: January 2023

Abstract
Romosinuano is a tropically adapted Bos taurus breed, and some Mexican breeders look to improve it genetically. The aim was to estimate allelic and genotypic frequencies for SNPs associated with meat quality in a Mexican Romosinuano population. Four hundred ninety-six animals were genotyped using the Axiom©BovMDv3 array. Only SNPs related to meat quality in this array were studied in this analysis. The Calpain, Calpastatin, and Melanocortin-4 receptor alleles were considered. Allelic and genotypic frequencies and Hardy-Weinberg equilibrium were estimated with the PLINK software. Principal component analysis was carried out with the meat quality SNPs information to determine stratification by haplotype in genes of the population. Alleles associated with meat tenderness, higher marbling score, and lower shear force were found in the Romosinuano cattle population. CAPN1_4751 was found in Hardy Weinberg equilibrium. The rest of the markers could be affected by selection and inbreeding. Romosinuano cattle in Mexico have similar genotypic frequencies in markers related to meat quality to Bos taurusbreeds known for their meat tenderness. Breeders can choose a marker-assisted selection to improve meat quality characteristics.
Submerged nanoporous anodized alumina structure for solar powered desalination
Authors: Kaviti Ajay , Akkala Siva Ram , Jeremias Michal , Pohorely Michael , Sikarwar Vineet Singh 
Published: January 2023

Abstract

Development of nano-porous structures utilizing a single step of anodization technique is well recognized as a cost-effective and straightforward approach for several applications. In the current work, anodized alumina was developed with nano-porous structure by utilizing oxalic acid as an electrolyte with a continuous voltage of 40 V. The formed nano-porous structure was subjected to desalination application because of its high absorbance of broadband solar spectrum energy. The desalination setup consists of two solar stills namely conventional and modified. The developed structure is placed in the modified still to examine its performance. It was observed that the structure distributing heat to surrounding water by absorbing photon energy from the sun through the nanopores and giving an efficient pathway to the water vapors for developing effective desalination. The nano-porous structure having ~ 45 nm average diameter. Furthermore, the band gap energy of nano-porous structure was found to be ~ 2.5 eV (Absorption Spectrum Fitting) and ~ 2.8 eV (Tauc plot). The nanoporous structure possess the visible light spectra in solar region which helps the band gaps of nanoporous structure to provide an additional supply of energy for generating more water to evaporate. Moreover, the urbach energy of the structure is 0.5 eV which reveals less defects in the modified still. The overall distillate yield of modified still was increased to 21% in contrast to conventional. Water quality analysis was also carried out before and after the desalination experiments and the results were within acceptable limits set by World Health Organization (WHO).
The effect on incisional hernia of absorbable barbed suture for midline fascial closure in minimally invasive surgery for colorectal and gastric cancers: study protocol for a prospective randomized controlled trial
Authors: Lee Sejin , Han Se Wung , Lee Min Ro , Kim Chan-Young , Ha Gi Won 
Published: January 2023

Abstract
Background: Incisional hernia following abdominal surgery is a frequent complication of midline laparotomy. This complication is strongly associated with the technique and material used for suture. While a monofilament absorbable suture is recommended to prevent incisional hernia, it can lead to suture loosening or surgical-knot breakage. Although barbed sutures can be an alternative suture material in abdominal fascial closure, evidence for its safety and effectiveness is lacking. Therefore, we designed a prospective randomized trial to evaluate the safety and efficacy of absorbable barbed sutures for midline fasciaclosure in minimally invasive surgery for colorectal and gastric cancers in comparison with conventional absorbable monofilament sutures.
Methods: A total of 312 patients who underwent minimally invasive surgery for colorectal and gastric cancers will be randomly allocated to either the absorbable barbed or monofilament suture group for abdominal fascia closure in a 1:1 ratio. The primary outcome is incisional hernia rate within three years after surgery, as verified by physical examination and computed tomography. Postoperative complications, including surgical site infection, postoperative pain, and quality of life, will be compared between two groups as secondary outcomes. The investigator will examine the patients until discharge and at 6, 12, 18, 24, and 36 months postoperatively.
Discussion: This is the first randomized controlled trial to compare absorbable barbed sutures with monofilament sutures for midline fascia closure in minimally invasive surgery. If absorbable barbed sutures demonstrate comparable results to those of monofilament sutures, this type of suture material may be recommended as an alternative option for abdominal fascia closure.
Trial registration: KCT0007069