bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Association Between Expanded ACEs and Behavioral Health Outcomes Among Youth at First Time Legal System Contact
Authors: Folk Johanna B. , Ramaiya Megan , Holloway Evan , Ramos Lili , Marshall Brandon D. L. , Kemp Kathleen , Li Yu , Bath Eraka , Mitchell Daphne Koinis , Tolou-Shams Marina 
Published: December 2022

AbstractA growing body of literature has documented high rates of adverse childhood experiences (ACEs) and their effects on behavioral health among adolescents impacted by the juvenile legal system. Most research with justice-impacted youth assesses the ten standard ACEs, encompassing abuse, neglect, and household dysfunction. This body of work has largely ignored the five expanded ACEs which assess social and community level adversity. Justice-impacted youth commonly experience expanded ACEs (racial discrimination, placement in foster care, living in a disadvantaged neighborhood, witnessing violence, bullying), and inclusion of these adversities may enhance predictive utility of the commonly used ACEs score. The current study examined the prospective impact of total ACEs (standard and expanded) on alcohol and cannabis use, substance-related consequences, and psychiatric symptoms during the year following first ever contact with the juvenile court. Results indicate justice-impacted youth experience multiple expanded ACEs prior to first court contact. The expanded ACEs did not predict any of the behavioral health outcomes assessed, over and above the standard ACEs. Inclusion of expanded ACEs in the standard ACEs score may not increase utility in identifying prospective behavioral health outcomes among youth in first time contact with the juvenile legal system.
Subdomain separability in global optimization
Authors: Deussen Jens , Naumann Uwe 
Published: December 2022

AbstractWe introduce a generalization of separability for global optimization, presented in the context of a simple branch and bound method. Our results apply to continuously differentiable objective functions implemented as computer programs. A significant search space reduction can be expected to yield an acceleration of any global optimization method. We show how to utilize interval derivatives calculated by adjoint algorithmic differentiation to examine the monotonicity of the objective with respect to so called structural separators and how to verify the latter automatically.
Study of irradiation decomposition products of PUREX solvents on zirconium metal retention behavior
Authors: Zhou Lei , Zhou Yu , Jiao Caishan , Zhang Meng , He Mingjian , Gao Yang 
Published: December 2022

AbstractThe metal retention behaviors of several simulated radiolysis products on zirconium metal were investigated, and it was found that acid phosphate radiolysis product HDEHP has the greatest effect. The effects of extraction nitric acid concentration, simulated radiolysis product concentration, metal concentration, and temperature on the zirconium metal retention behavior were also investigated. The results showed that zirconium metal forms complexes with HDEHP resulting in retention in the organic phase. Nitric acid concentration and metal concentration change the morphology of the metal thus affecting the extraction and metal retention behavior. The temperature has almost no effect on metal retention.
Are some controversial views in bioethics Juvenalian satire without irony?
Authors: Häyry Matti 
Published: December 2022

AbstractThe article examines five controversial views, expressed in Jonathan Swift’s A Modest Proposal, Helga Kuhse and Peter Singer’s Should the Baby Live? The Problem of Handicapped Infants, Alberto Giubilini and Francesca Minerva’s “After-birth abortion: why should the baby live?”, Julian Savulescu’s “Procreative beneficence: why we should select the best children”, and the author’s “A rational cure for prereproductive stress syndrome”. These views have similarities and differences on five levels: the grievances they raise, the proposals they make, the justifications they explicitly use, the justifications they implicitly rely on, and the criticisms that they have encountered. A comparison of these similarities and differences produces two findings. First, some controversial views based on utilitarian considerations would probably fare better flipped upside down and presented as Juvenalian satires. Secondly, a modicum of humor or modesty could help presenters of controversial views to stir polite critical discussion on the themes that they put forward.
Fast and universal estimation of latent variable models using extended variational approximations
Authors: Korhonen Pekka , Hui Francis K. C. , Niku Jenni , Taskinen Sara 
Published: December 2022

AbstractGeneralized linear latent variable models (GLLVMs) are a class of methods for analyzing multi-response data which has gained considerable popularity in recent years, e.g., in the analysis of multivariate abundance data in ecology. One of the main features of GLLVMs is their capacity to handle a variety of responses types, such as (overdispersed) counts, binomial and (semi-)continuous responses, and proportions data. On the other hand, the inclusion of unobserved latent variables poses a major computational challenge, as the resulting marginal likelihood function involves an intractable integral for non-normally distributed responses. This has spurred research into a number of approximation methods to overcome this integral, with a recent and particularly computationally scalable one being that of variational approximations (VA). However, research into the use of VA for GLLVMs has been hampered by the fact that fully closed-form variational lower bounds have only been obtained for certain combinations of response distributions and link functions. In this article, we propose an extended variational approximations (EVA) approach which widens the set of VA-applicable GLLVMs dramatically. EVA draws inspiration from the underlying idea behind the Laplace approximation: by replacing the complete-data likelihood function with its second order Taylor approximation about the mean of the variational distribution, we can obtain a fully closed-form approximation to the marginal likelihood of the GLLVM for any response type and link function. Through simulation studies and an application to a species community of testate amoebae, we demonstrate how EVA results in a “universal” approach to fitting GLLVMs, which remains competitive in terms of estimation and inferential performance relative to both standard VA (where any intractable integrals are either overcome through reparametrization or quadrature) and a Laplace approximation approach, while being computationally more scalable than both methods in practice.
Are animal breeds social kinds?
Authors: Vidal Oriol , Teira David 
Published: December 2022

AbstractBreeds are classifications of domestic animals that share, to a certain degree, a set of conventional phenotypic traits. We are going to defend that, despite classifying biological entities, animal breeds are social kinds. We will adopt Godman’s view of social kinds, classifications with predictive power based on social learning processes. We will show that, although the folk concept of animal breed refers to a biological kind, there is no way to define it. The expert definitions of breeds are instead based on socially learnt conventions and skills (artificial selection), yielding groupings in which scientific predictions are possible. We will discuss in what sense breeds are social, but not human kinds and in what sense the concept of a breed is necessary to make them real.
The Sceptic, The Outsider, and Other Minds
Authors: Avramides Anita 
Published: December 2022

AbstractThe usual way with scepticism is to formulate a problem in connection with the external world and then apply this to other minds. Drawing on work by Stanley Cavell and Richard Moran, I argue that the sceptic misses an important difference in our concepts of mind and of body, and that this is reflected in the sceptic’s formulation of a problem regarding other minds. I suggest that an understanding of this important conceptual difference is also missing from the work of those who attempt to reply to (dismiss, or ignore) the sceptic. In this connection I discuss both inferential and perceptual accounts of our knowledge of other minds. I identify an error in these accounts that may be thought to arise from a lack of understanding of the important conceptual difference here, and then develop an understanding of this error that draws on the work of Edith Stein and Stanley Cavell.
Distorted Debates
Authors: Picazo Claudia 
Published: December 2022

AbstractOne way to silence the powerless, Langton has taught us, is to pre-emptively disable their ability to do things with words. In this paper I argue that speakers can be silenced in a different way. You can let them speak, and obscure the meaning of their words afterwards. My aim is to investigate this form of silencing, that I call retroactive distortion. In a retroactive distortion, the meaning of the words of a speaker is distorted by the effect of a subsequent speech act by a different speaker. After introducing this notion, I explore some reasons why retroactive distortions can be difficult to challenge and argue that, besides constituting a communicative injustice, they can eliminate topics from public consideration and therefore erode public debate.
CT volumetry performs better than nuclear renography in predicting estimated renal function one year after living donation
Authors: Almeida Manuela , Pereira Pedro R. , Ramos Miguel , Carneiro Diogo , Mandaleno Mariana , Silva Filipa , Pedroso Sofia , França Manuela , Martins La Salete , Malheiro Jorge 
Published: December 2022

AbstractThe evaluation of split renal function (SRF) is a critical issue in living kidney donations and can be evaluated using nuclear renography (NR) or computerized tomography (CT), with unclear comparative advantages. We conducted this retrospective study in 193 donors to examine the correlation of SRF assessed by NR and CT volumetry and compared their ability to predict remaining donor renal function at 1 year, through multiple approaches. A weak correlation between imaging techniques for evaluating the percentage of the remaining kidney volume was found in the global cohort, with an R2 = 0.15. However, the Bland–Altman plot showed an acceptable agreement (95% of the difference between techniques falling within − 8.51 to 6.11%). The predicted and observed eGFR one year after donation were calculated using the CKD-EPI, and CG/BSA equations. CT volume showed a better correlation than NR for both formulas (adjusted R2 of 0.42. and 0.61 vs 0.37 and 0.61 for CKD-EPI and CG/ BSA equations, respectively). In non-nested modeling tests, CT volumetry was significantly superior to NR for both equations. CT volumetry performed better than NR in predicting the estimated renal function of living donors at 1-year, independently from the eGFR equation.
Plant growth-promoting properties of the phosphate-solubilizing red yeast Rhodosporidium paludigenum
Authors: Chen Yi-Ru , Kuo Chih-Yen , Fu Shih-Feng , Chou Jui-Yu 
Published: December 2022

AbstractPhosphorus (P) is one of the essential elements that are necessary for plant development and growth. However, the availability of soluble forms of P for plants in the soils is limited, because a large proportion of it is bound to soil constituents. Thus, the concentration of P available to plants at any time is very low and, moreover, its availability depends on the soil pH. As a solution, phosphate-solubilizing microorganisms (PSMs) are employed that render inorganic P available to plants in soluble form. Thus far, research into PSMs has been insufficient, and only few such organisms have been considered for exploitation as microbial fertilizer strains. The characteristics of plant growth promotion with the plant-PSMs coculture system remain to be elucidated. In the current study, we report on the isolate Rhodosporidium paludigenum JYC100 that exhibits good performance for solubilizing calcium phosphate. We found that it can be regulated by the amount of soluble phosphate. Furthermore, R. paludigenum JYC100 promotes plant growth under specific conditions (P deficiency, but with insoluble phosphate) in different media and soil pots. In contrast, the yeast Aureobasidium pullulans JYC104 exhibited weak phosphate-solubilizing capacities and no plant growth-promoting ability. Compared to control plants, the biomass, shoot height, and cellular inorganic P content of plants increased in plants cocultivated with R. paludigenum JYC100. In addition, histochemical GUS and qRT-PCR assays of phosphate starvation-induced (PSI) genes showed that the transcript levels of these PSI genes are decreased in the plants cocultured with R. paludigenum JYC100. These findings reflect the unique ability of R. paludigenum JYC100 to convert insoluble P compounds to plant-available P, thereby leading to growth promotion. Our study results highlight the use of yeasts as potential substitutes for inorganic phosphate fertilizers to meet the P demands of plants, which may eventually improve yields in sustainable agricultures.
Living in the World by Dying to the Self: Swami Vivekananda’s Modernist Reconfigurations of a Premodern Vedāntic Dialectic
Authors: Barua Ankur 
Published: December 2022

AbstractThis article is an exploration of the dialectic of this-worldly activism and the practice of self-effacement in Swami Vivekananda’s discourses. He often exhorts his audiences to cultivate the vigorous strength to live courageously in the world on the basis of their spiritual conviction that they are rooted in the true self (ātman) beyond all spatiotemporal limitations. The boundlessātman, to be realized by effacing the egocentric self, would become the imperishable source of their fortitude to live with fearlessness in a world of suffering. Since theātmanis not constrained by the egocentric bounds of the “I”, to become recentered in its illimitable heart is to move towards a universal morality. Through this return to one’s imperishable center of existential gravity, one transcends fear and hatred of the “other” as a radically alien being. While his socioreligious worldview is imprinted with aspects of Advaita as formalized by Śaṅkara, he also occasionally endorses the theocentric visions of Rāmānuja and Madhva and declares that all these Vedāntic pathways point towards the effacement of the ego and the generation of fearlessness.
Early recombinant human growth hormone treatment improves mental development and alleviates deterioration of motor function in infants and young children with Prader–Willi syndrome
Authors: Cheng Ruo-Qian , Ying Yan-Qin , Qiu Zheng-Qing , Fu Jun-Fen , Gong Chun-Xiu , Yang Yan-Ling , Shi Wei , Li Hui , Ma Ming-Sheng , Wang Chang-Yan , Liu Min , Chen Jia-Jia , Su Chang , Luo Xiao-Ping , Luo Fei-Hong , Lu Wei 
Published: December 2022

AbstractBackgroundRecombinant human growth hormone (rhGH) therapy has shown to improve height and body composition in children with Prader–Willi syndrome (PWS), the evidence of early rhGH treatment on motor and mental development is still accumulating. This study explored the time effect on psychomotor development, anthropometric indexes, and safety for infants and young children with PWS.MethodsA phase 3, single-arm, multicenter, self-controlled study was conducted in six sites. Patients received rhGH at 0.5 mg/m2/day for first four weeks, and 1 mg/m2/day thereafter for up to 52 weeks. Motor development was measured using Peabody Developmental Motor Scales-second edition, mental development using Griffiths Development Scales-Chinese (GDS-C). Height standard deviation score (SDS), body weight SDS, and body mass index (BMI) SDS were also assessed.ResultsThirty-five patients were enrolled totally. Significant improvements were observed in height, body weight, and BMI SDS at week 52; GDS-C score showed significant improvement in general quotient (GQ) and sub-quotients. In a linear regression analysis, total motor quotient (TMQ), gross motor quotient (GMQ), and fine motor quotient were negatively correlated with age; however, treatment may attenuate deterioration of TMQ and GMQ. Changes in GQ and locomotor sub-quotient in < 9-month group were significantly higher than ≥ 9-month group. Mild to moderate severity adverse drug reactions were reported in six patients.ConclusionFifty-two-week treatment with rhGH improved growth, BMI, mental development, and lessened the deterioration of motor function in infants and young children with PWS. Improved mental development was more pronounced when instituted in patients < 9 months old.
Experienced nursery teachers gaze longer at children during play than do novice teachers: an eye-tracking study
Authors: Sadamatsu Joe 
Published: December 2022

AbstractDespite the widespread recognition of the significance of outdoor play in early childhood development, centers for early childhood education (ECE) face the challenge of striking a balance between active play activities and safety concerns. Thus, the visual attention of teachers is critical. Studies that compare the visual attention of novice and experienced teachers traditionally focus on instructional settings instead of recreational play. This study examines the effect of experience on the attentional focus of teachers on children’s play in ECE settings in Japan. Eye-tracking data were collected from 10 novices and 10 relatively experienced ECE staff members to compare fixation location, number of fixation, and fixation duration while groups of 3-year-old children played in a sandbox. The results of the independent sample t tests revealed that experienced teachers gazed at the children more frequently than did novice teachers; however, the mean fixation duration was significantly shorter among relatively experienced teachers across all participants. Similarly, although experienced teachers spent more time overall than did novice teachers in observing the children and peripheral areas of the play area as they played, the mean fixation duration was significantly shorter than that of novice teachers. The findings support other studies that highlight the heightened ability of experienced teachers to assess conditions more quickly and draw conclusions regarding the activities of children. In addition, the findings support research that reports that the level of supervision and control imposed by ECE teachers on children’s play and safety are closely related to their level of experience.
Food insecurity and disasters: predicting disparities in total and first-time food pantry visits during the COVID-19 pandemic
Authors: Drake Alexandria J. , Phillips Lora A. , Karna Brajesh , Murugesan Shakthi Bharathi , Villa Lily K. , Smith Nathan A. 
Published: December 2022

AbstractIn the U.S. state of Arizona, nearly one-third of households experienced food insecurity during the COVID-19 pandemic, an increase from one-fourth of households before the pandemic. Previous research on food insecurity in the wake of natural and human-instigated disasters demonstrates that groups vulnerable to food insecurity before a disaster are more susceptible to food insecurity during and after that disaster; however, less is known about whether this relationship also holds true during health-related disasters, such as the COVID-19 pandemic. We explore how the COVID-19 pandemic influenced urban food insecurity patterns by analyzing the socio-demographic characteristics of food pantry clients in Maricopa County, Arizona. Using data from Phoenix Rescue Mission (PRM), a local non-profit food service provider, two binomial logistic regression models compare the socio-demographic composition of total and first-time food pantry users before and during the pandemic. In addition to an overall increase in food pantry usage during the pandemic, we find that, while certain socio-demographic groups historically vulnerable to food insecurity experienced the predicted uptick in insecurity during the pandemic, other socio-demographic disparities were attenuated. These somewhat disparate findings illustrate the complex relationship between disasters and food insecurity in an urban context, offering several avenues for future research.
Land sharing complements land sparing in the conservation of disturbance-dependent species
Authors: Tälle Malin , Öckinger Erik , Löfroth Therese , Pettersson Lars B. , Smith Henrik G. , Stjernman Martin , Ranius Thomas 
Published: December 2022

AbstractAlteration of natural disturbances in human-modified landscapes has resulted in many disturbance-dependent species becoming rare. Conservation of such species requires efforts to maintain or recreate disturbance regimes. We compared benefits of confining efforts to habitats in protected areas (a form of land sparing) versus integrating them with general management of production land (a form of land sharing), using two examples: fire in forests and grazing in semi-natural grasslands. We reviewed empirical studies from the temperate northern hemisphere assessing effects of disturbances in protected and non-protected areas, and compiled information from organisations governing and implementing disturbances in Sweden. We found advantages with protection of areas related to temporal continuity and quality of disturbances, but the spatial extent of disturbances is higher on production land. This suggests that an approach where land sparing is complemented with land sharing will be most effective for preservation of disturbance-dependent species in forests and semi-natural grasslands.
A versatile untargeted metabolomics-driven technology for rapid phytochemical profiling of stem barks of Zanthoxylum species with antioxidant and antimicrobial activities
Authors: Kaigongi Magrate M. , Lukhoba Catherine W. , Musila Fredrick M. , Taylor Malcolm , Mbugua Regina W. , Githiomi Joseph , Yenesew Abiy , Makunga Nokwanda P. 
Published: December 2022

AbstractZanthoxylum species are credited with various uses in ethnomedicine due to their rich metabolite composition. In Kenya, these include management of cancer and microbial related ailments. However, there are limited reports showing how the bioactivity of Kenyan Zanthoxylum species is linked to their phytochemical profiles. This study therefore aimed at examining the chemical variation among five Zanthoxylum species found in Kenya (Z. chalybeum, Z. gilletii, Z. holtzianum, Z. paracanthum and Z. usambarense) using metabolomics approaches and the anti-oxidant and antimicrobial activities of these species. In a Folin–Ciocalteu test, the phenolic content of the stem bark extracts of these species were 73.083–145.272 mg TAE/g, while the alkaloids (in bromothymol blue chromogenic test) and flavonoids (in aluminium chloride test) were found to be 152.39–207.19 mg ME/g, and 109.416–186.413 mg CE/g, respectively. These extracts also exerted strong antioxidant activities in the 2,2-iphenyl-1-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power assays. In a broth dilution assay, the extract of the stem bark of Z. holtzianum ability showed the highest antimicrobial activity, followed by Z. chalybeum stem bark extract. The activities were positively correlated to both flavonoids and alkaloids concentrations, while the concentration of phenolics had weak negative correlation to antimicrobial activities. A chemometric analysis of the liquid-chromatography mass spectrometry profiles led to grouping of the species into three clusters. This study illustrates the variation in the bioactivity of Zanthoxylum species based on metabolite composition and justifies the wide usage of Zanthoxylum species in Kenyan traditional medicinal practices.
Graphical abstract