bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Potential Drug-Drug Interactions in Obese Patients
Authors: ÖZDAMAR Emine Nur , MUTLU Hacer Hicran 
Published: September 2023

Aim: Polypharmacy may cause life-threatening adverse effects due to drug-drug interactions (DDIs). It is possible to observe DDIs due
to polypharmacy in obese patients who is known to have many co-morbid diseases that necessitates multiple drug use. The aim of the
present study is to determine the frequency and severity of potential DDIs (pDDIs) in obese patients.
Material and Methods: This cross-sectional study analyzed the patient charts that admitted to obesity outpatient clinic of tertiary care
hospital from April 1, 2016 to July 1, 2017. The severity of DDIs was interpreted using the Lexi-comp® drug interaction database. A chisquare
test was performed for the comparison of the presence of DDIs based on patients’ demographic characteristics [gender (male/
female), age categories (18-44, 45-64 and ≥65 years) and BMI (30-34.9, 35-39.9 and ≥40 kg/m2)], co-morbid clinical conditions and
number of drugs. The comparisons were considered as statistically significant at p< 0.05.
Results: Out of 476 patient data evaluated, a total of 781 drugs were prescribed. Among 190 patients who were prescribed two or more
drugs, 35 (18.4%) patients had one or more pDDIs. We determined 48 (70.6%) C, 12 (17.6%) B, 7 (10.3%) D and 1 (1.5%) X risk category
interactions. The most common pDDIs were between metformin and nonsteroidal anti-inflammatory drugs (7.4%). The presence of
pDDIs was significantly associated with the number of prescribed drugs (p
Weight Matters: Investigating Overweight and Obesity Prevalence Among Municipal Bus Drivers and Its Nexus with Physical Activity, Stress, Emotional Eating, and Diet
Authors: GÜNAL Ahmet Murat 
Published: September 2023

Aim: This study aims to investigate the prevalence of overweight and obesity among municipal bus drivers in İstanbul province and
explore the intricate relationships between weight status, physical activity levels, stress perception, emotional eating tendencies, and
dietary patterns within this occupational group.
Material and Methods: A cross-sectional study was conducted with the participation of 380 bus drivers. Data were collected through
face-to-face interviews using a data collection tool consisting of an information form, the International Physical Activity Questionnaire
Short Form (IPAQ-SF), the Perceived Stress Scale (PSS), the Emotional Eating Scale (EES), and 24-hour Dietary Recall.
Results: The findings revealed that 85.8% of the participants were overweight (52.6%) or with obesity (33.2%). The mean PSS score
was 25.8±6.7, and the mean EES score was 29.3±10.8. The participants exhibited low physical activity levels (96.1%), with a mean
of 246.2±165.4, signifying inactivity. Weak positive correlations were found between PSS and ESS scores. Dietary analysis showed a
moderate energy intake of 1674.4±429.5 kcal. Individual variability in energy intake and nutrient consumption patterns was evident.
Conclusion: The high prevalence of overweight and obesity among municipal bus drivers highlights the importance of targeted
interventions for improved lifestyle and reduced health risks in this occupational group.
Antimicrobial Effect of German chamomile Extractas Root Canal Irrigant (in vitro Study)
Authors: D. Salman Faraed 
Published: September 2023

Aims: To evaluate the antimicrobial effect of German chamomile extract as a root canal irrigant in vitro, and comparing its effect with chlorhexidine 0.2% irrigant solution.
Materials and Methods: Twenty adult patients with age range 18-40 years attending dental school with symptomatic uniradicular teeth with necrotic pulp diagnosed by radiograph with no fistula or sinus tract were chosen; 10 subjects for each irrigant solution (the test and the control groups). Microbiological samples were obtained from the root canal at the beginning of the first appointment, and then moistened paper point is placed in a screw capped vial containing 5 ml Thioglycolate broth for anacrobic bacteria and the other containing Brain Heart Infusion broth for aerobic bacteria, which is incubated directly for 18 hours at 37 °C. Turbidity test was used to compare antimicrobial effect of German chamomile extract with chlorhexidine 0.2%.
Results: Mean reduction in bacterial count (0.36 + 0.09 for acrobic and 0.19 + 0.02 for anacrobic) for German chamomile and chlorhexidine 0.2% (0.084 + 0.03 and 0.052 + 0.016 respectively) were determined by using onc sample t-test, which was much lower for German chamomile than for chlorhexidine 0.2% with significant difference. For comparison between two materials for acrobic and anacrobic, unpaired t-test was used. Results were considered significant at p < 0.05.
Conclusion: German chamomile extract is effective antimicrobial irrigant solution especially on anaerobic bacteria but much lower than chlorhexidine 0.2% irrigant solution.
Topical Nitroglycerin versus Lateral fnternal Sphincterotomyin Treatment of Chronic Anal Fissure
Authors: Allaw Makki 
Published: September 2023

Background: Anal fissure is common conditions that can affect people of all ages. Most anal fissures are at the rear of anal opening in line with cleft of the buttocks. There are many methods of treatment such as: medication by topical nitroglycerin or nifedipine paste or butulinum toxin injection or surgery by lateral internal Sphincterotomy or V-Y advancement flap.
Objectives: Is to compare the result of topical GTN (chemical Sphincterotomy) as primary treatment of chronic anal fissure with lateral internal Sphincterotomy.
Methods:
Setting: In outpatient clinic and Tikrit teaching hospital from Jan. 2006 to Oct0.2007.
Design: prospective study.
This study compares the results of two different methods of treatment (chemical sphinecterotomy&lateral internal Sphincterotomy) in 84 cases of chronic anal fissure regarding the efficacy and complication of these procedures.
These cases were randomized in equal number into two groups:
Group 1: were treated by chemical Sphincterotomy.
Group 2: were treated by lateral internal Sphincterotomy.
The average period of follow up after completion of treatment was 3 months for both groups.
Results:
Symptomatic improvement occurs in 30 patients treated by chemical Sphincterotomy (71.42%) at 12 weeks following treatment and 39 patients (92.85%) treated by lateral internal Sphincterotomy.
No improvement occurs in 3 cases (7.15%) treated by chemical Sphincterotomy and no case who was treated by lateral internal Sphincterotomy.
Conclusion: From this study we find that chemical Sphincterotomy induce rapid healing of chronic anal fissure with 71.42% rate in comparison to lateral internal Sphincterotomy with a 92.85% healing rate after 12 weeks treatment,
The Impact of Female Leadership Style on Team Creativity in Rising English Education Group in China
Authors: Ruiyao Ma , Keat Ooi Boon , Ahmad Albattat 
Published: September 2023

Purpose: Corporate innovation might be slowed by team creativity and other factors. When a company's team creativity is low, innovation suffers, impacting its market competitiveness and technological advancement. Low-creativity teams make more mistakes, slowing down the project and making it more difficult to achieve its goals. Teams who do not innovate will not be able to expand or compete. The impact of female entrepreneurs' leadership styles on team innovation has not been researched in China's education administration. This study will look at how the leadership styles of successful female business owners promote innovative teamwork.

Theoretical framework: This study developed a theoretical model based on the constitutive theory of creativity, with transformational leadership, empowering leadership, authoritative leadership, and participative leadership as independent variables, entrepreneurial team creativity as the dependent variable, team psychological empowerment as the mediating variable, and the nature of the company's business as the moderating variable.

Methodology: This research looks at how strong female leaders help Rise English Educational Organization. This study looks at how different female leadership styles affect group morale, effectiveness, and innovation.

Research, Practical & Social implications: Through a review of existing literature and similar studies, this chapter outlines the theoretical model and related hypotheses of this study and provides a more specific direction for the accompanying empirical investigation. Female team leaders frequently place a high importance on effective communication and collaboration. They promote open dialogue, paying attention, and making valuable comments. These modes of communication make it easier for people to share ideas and collaborate, which is beneficial to team innovation. When their manager is a woman, team members who feel mentally encouraged are more inclined to think imaginatively, take the initiative, and help solve difficulties.

Originality/value: This beneficial relationship between a woman's leadership style and the psychological freedom of the team can encourage team members to be more creative and imaginative. Team psychological strength can help explain the connection between how a woman leads and how creative her team is, but it is not the sole factor influencing team creativity. The objective of the business, the people on the team, and the tools available can all have an impact on team creativity.
EFL Teachers' and Students' Attitudes and Practices Regarding Oral Communication in English Classes: Ethiopian High School Context
Authors: Sada Eyasu Yaya , Bulbula Dereje Asfaw , Bulti Tesfa Alemu 
Published: September 2023

This study looked at the attitudes of Ethiopian English teachers and Bonga Mehal Ketema High School grade 10 students about spoken communication in the classroom. The purpose of this study was to determine why oral communication is such an important part of English teaching, what role teachers and students play in making orally active students in the English classroom. Four English teachers were purposively interviewed, and 95 pupils in the tenth grade completed a questionnaire. The findings show that the majority of teachers and students believe that oral communication is an important aspect of the English education process. It is primarily due to the fact that being able to express yourself vocally in English in today's world is extremely important. The findings also reveal that teachers believe assessing students' oral competence is difficult since it is not as concrete as other abilities assessed in the English foreign language course. The challenge of convincing timid or unmotivated students to engage orally, as well as a lack of time, make assessing students a challenging undertaking. Thus, EFL teachers should establish a welcoming environment in the classroom to help students enhance their speaking skills.
Diagnostic Accuracy of the Carbon Dioxide Gap (ΔCO2) in Predicting the Return of Spontaneous Circulation: A Prospective Single Center Study
Authors: İSLAM Mehmet Muzaffer , AKSEL Gökhan , EROĞLU Serkan Emre , YÖNAK Hayrullah 
Published: September 2023

Aim: The carbon dioxide gap or ΔCO2 is the difference between the partial pressure of carbon dioxide
(pCO2 ) and end-tidal carbon dioxide (ETCO2 ), which should normally not exceed 3-5mmHg. In critically ill
patients ΔCO2 increases as a result of decreased cardiac output and pulmonary blood flow compromise.
The primary outcome of this study is to examine the diagnostic accuracy of ΔCO2 in predicting the return
of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) patients.
Material and Methods: Non-traumatic OHCA patients over 18 years of age were included in this
prospective observational study. ETCO2 values were recorded 1 minute after the intubation and arterial
blood gas samples were acquired simutaneously. The difference between the initial ΔCO2 medians of
the ROSC+ and ROSC- patient groups were analyzed and the diagnostic test performance in predicting
ROSC of ΔCO2 was calculated. A regression model was performed to accurately predict ROSC in
OHCA patients.
Results: A total of 46 patients were included to the inal analysis. The ΔCO2 median of the ROSC+ group
was significantly lower than the ROSC- group (p=0.026, 95%CI:-31 to-3). Area under the curve was
calculated as 0.694 (95%CI: 0.532 to 0.855), sensitivity 76.19% (95%CI:52.83 to 91.78%), specificity
76% (95%CI:54.87 to 90.64), and accuracy 76.09% (95%CI:61.23% to87.41%) for the optimal cut-off
value (51.4 mmHg). The regression model consists of age, initial ETCO2 , and initial cardiac rhythm
showed good discrimination in predicting ROSC (AUC=0.846, 95%CI=0.735 to 0.956, p
Efficacy and Safety of Prostate Radiofrequency Thermotherapy in Elderly Patients with BPO and Nocturia Resistant to Alpha-Blocker Therapy: An Observational Study
Authors: YÜCE Ahmet , YAZICI İbrahim , BENLİ Erdal , ÇIRAKOĞLU Abullah , NALBANT İsmail 
Published: September 2023

Aim: The purpose of this study is to investigate the effectiveness of the prostate bipolar radiofrequency
thermotherapy method on the complaint of nocturia and its safety in elderly patients.
Material and Methods: The post-procedural results of 100 patients over the age of 65 with complaints of
refractory nocturia were examined. The patients' pre-procedural Qmax values, prostate volumes, postvoid
residual amounts, IPSS scores, frequency of nocturia, and associated quality of life questionnaire
scores were recorded and compared with the results at the 3rd month after the procedure.
Results: The pre-procedural and post-procedural nocturia frequencies of the patients were consecutively
4.1 (2-13) times and 2.1 (0-10)times (p=0.002). There were significant improvements in the N-QOL
scores of the patients by 1.70±0.7 and in their discomfort caused by voiding at night (p
Clinico-Epidemiological Profile of Immunocompetent Patients Diagnosed with Herpes Zoster: A Single-Center Retrospective Cohort Study from Sinop
Authors: KESKİNKAYA Zeynep , SARİYEVA ISMAYİLOV Ayna , AYDIN GÜÇLÜ Özge 
Published: September 2023

Aim: Herpes zoster (HZ) mainly occurs in immunocompetent individuals, even though immunosuppression
is a well-known risk factor. The aim of this study was to evaluate the demographic and clinical features
of immunocompetent HZ patients and HZ-related complications with a special focus on possible
contributing factors.
Material and Methods: This single-center, retrospective cohort study included 98 patients with no
known immunosuppressive condition out of 103 patients diagnosed with HZ between September 2019
and August 2020. The patients were evaluated in terms of age, sex, medical history, clinical features,
triggering factors, seasonality, complications, and neutrophil-to-lymphocyte ratio (NLR) as a marker of
systemic inflammation.
Results: Ninetyeight immunocompetent patients (male:female ratio=1.1:1) were diagnosed with HZ,
with a median age of 59 years (age range: 5-88). Thoracic dermatome was the leading dermatome
(n=45). Trigeminal nerve was involved in 11 patients, eight of them presenting with ophthalmic HZ. HZ
attacks were mainly detected in summer, while ophthalmic HZ cases were exclusively diagnosed during
fall and winter. Two patients developed ophthalmic HZ following trauma. Eleven patients experienced
postherpetic neuralgia (PHN) during follow-up with a male predominance (p=0.009). A higher mean NLR
value was detected in PHN patients, although it was not statistically significant (p=0.136).
Conclusion: The findings of our study are compatible with the current literature regarding the main
presentation pattern of HZ as unilateral thoracic dermatome involvement and the complications such as
PHN and ophthalmic HZ occurring in a subgroup of patients. The high HZ incidence rate in our series is
likely due to the high median age of the population in our region. The summer peak of HZ cases further
supports the seasonal variability due to the ultraviolet effect, whereas mechanical trauma is another
possible triggering factor. The predictive value of NLR for PHN should be evaluated in further studies.
COVID-19 Kapanmasının Yaşa Bağlı Makula Dejenerasyonu Tedavisine Etkileri
Authors: BİLİCİ Serdar , ŞAHİN-ELARSLAN Kardelen Ezgi 
Published: September 2023

Amaç: Yaşa bağlı makula dejenerasyonu (YBMD) olgularında COVID-19 kapanması nedeniyle yaşanan
intravitreal anti-vasküler büyüme faktörü (VEGF) tedavisindeki gecikmenin anatomik ve fonksiyonel
etkilerinin değerlendirilmesi amaçlandı.
Gereç ve Yöntemler: COVID-19 nedeniyle anti-VEGF tedavisine ara verilen YBMD olguları çalışmaya
dahil edildi. Olguların yaş, cinsiyet, tedaviye verilen ara süresi ve tekrar tedavi sonrası enjeksiyon
sayısı ile takip süresi kaydedildi. Karantina öncesi son vizitleri (V0), karantina sonrası ilk (V1) ve son
vizitlerindeki (V2) görme keskinlikleri (GK) ve optik koherans tomografi ile santral makula kalınlığı (SMK)
değerlendirildi. Olgular tedaviye verilen ara süresine göre 18 hafta ve altı (Grup-1) ile 18 hafta üzeri
(Grup-2) olarak alt gruplara ayrıldı.
Bulgular: Çalışmaya yaş ortalaması 73,1 olan 53 olgunun 53 gözü dahil edildi. Pandemi sürecinde
tedaviye verilen ara ortalaması 26,4 ± 10,6 haftaydı. Tekrar tedaviye başlanan olguların ortalama takip
süresi 32,5 (9-52) hafta olup bu süreç içerisinde ortalama 3,84 (1-9) anti-VEGF tedavi uygulanmıştır.
Tüm grupta V0, V1 ve V2 vizitlerindeki ortalama GK sırasıyla 0,78, 0,98 ve 0,89 LogMAR, ortalama
SMK değerleri sırasıyla 371,3, 430,8 ve 334,2 mikron bulunmuştur (Sırasıyla p=0,001 ve p=0,010).
Grup 1’ de V0, V1 ve V2 vizitlerindeki ortalama GK sırasıyla 0,78, 0,89 ve 0,86 LogMAR; ortalama SMK
değerleri sırasıyla 374,5, 378,2 ve 308,2 mikron olarak bulunmuştur (Sırasıyla p=0,272 ve p=0,761).
Grup 2’de V0, V1 ve V2 vizitlerindeki ortalama GK sırasıyla 0,78, 1,03 ve 0,9 LogMAR; ortalama SMK
değerleri sırasıyla 369,6, 457,8 ve 347,5 olarak bulunmuştur (Sırasıyla p=0,006 ve p=0,005).
Sonuç: YBMD olgularında anti-VEGF tedavisine ara verilmesiyle birlikte anatomik ve fonksiyonel olarak
kötüleşme izlenmiştir. Tekrar tedaviye başlanması ile SMK’ da düzelme olmasına rağmen GK kaybı
kalıcı olmuştur.
Myopia in the COVID-19 Pandemic Period in Young Adults: The Sample of Turkey-Zonguldak
Authors: KAYA Pınar , ÜÇGÜL ATILGAN Cemile 
Published: September 2023

Aim: Investigating the relationship between the development and progression of myopia and digital
screen time in young adults during the COVID-19 pandemic.
Material and Methods: This single-centered, retrospective study included 106 young adults aged 18-
25 years, followed up in January-March 2019, 2020, and 2021. The patients were divided into two
groups: emmetrope and myopia according to their baseline refractive values. The association between
spherical equivalent refraction (SER) values and digital screen time before and during the pandemic
was evaluated.
Results: The mean age of 59 patients‘ (69.5% female) in the emmetrope group was 20.7±2.0, and
20.6±2.3 years of 47 patients (68.1% female) in the myopia group (p=0.422, p=0.877, respectively).
The patients were reported to spend more time on digital devices in both groups (p
Use of Various Types of Chitosan as Edible Coating to Maintain Physical Quality of Tomatoes (Solanum lycopersicon L.) During Storage at Two Different Temperatures
Authors: Nasution Novia Asri , Idris M. 
Published: September 2023

Increasing tomato production requires special handling to increase longer shelf life by applying chitosan and modifying storage temperatures. Chitosan is a chitin derivative whose function is similar to wax compounds so that it is able to inhibit metabolic activity. Storage temperature of 10°C can extend shelf life and maintain the physical quality of tomatoes. This study aims to determine the effect of chitosan administration, the effect of storage temperature, and the effect of the combination of chitosan and storage temperature on the physical quality of tomatoes. This study used a Factorial Complete Randomized Design, the first factor was tomatoes without chitosan coating (K0), and tomatoes with chitosan coating (K1) = shrimp shell, (K2) = crab shell, (K3) = fish scales using the same concentration of 6%. The second factor is storage temperature (T1) = room temperature (26-32°C) and (T2) = temperature 10°C. The changes observed are shrinkage in weight, color, texture, aroma, taste based on organoleptic test (hedonic test). Data analysis using ANOVA at 5% level and BNJ follow-up test at 5% level. The results showed that the use of crab chitosan (K2) had an effect on weight loss (0.42%). Storage temperature of 10°C (T2) affects weight loss (5.04%). The best treatment combination for weight loss (0.07%) and color (7.40) was crab chitosan and temperature of 10°C (K2T2), while the best treatment combination for texture (7.56), aroma (7.08), and taste (7.16) was fish scales and temperature of 10°C (K3T2). In general, the best treatment is chitosan fish scales and a temperature of 10°C (K3T2).
Effect of NPK Dose (16:16:16) on Growth and Yield of Cayenne Chili (Capsicum frutescens L.) in Tasikmalaya
Authors: Amanda Adinda Putri , Mulyana Muhammad Agus , Wahyuningtyas Aulia 
Published: September 2023

Cayenne pepper (Capsicum annum L.) is one type of chili that has high demand in Tasikmalaya. To fulfill the consumption, cayenne pepper production is needed to be added. This study helps to determine the best dose of NPK fertilizer that can support the growth yield of cayenne pepper, especially in Tasikmalaya. The research was conducted in experimental field of Agriculture Faculty Universitas Perjuangan Tasikmalaya from November 2022 until February 2023. Experimental design used a randomized block degisn of single factor with six treatments and three replications. The treatments consist of no NPK fertilizer, ( ¼ , ½ , ¾ , 1 and 1 ¼ ) doses of NPK fertilizer. The results showed that NPK fertilizer had an affect on plant hight with 15.6 cm (3 WAP), 20.4 cm (4 WAP), 24,5 (5 WAP), 27,5 (6 WAP) and 29.5 cm (7 WAP). The highest cumulative yield of cayenne pepper from 1st until 3th harvests with fruit weight plant-1 was the 1 dose NPK treatment of 358,08 g plant-1.
Protease Enzyme Activity of Fungal Isolates from Avocado and Coconut Fleshes on Different pH and Temperature
Authors: Sedijani Prapti , Lestari Dinda Propita , Rasmi Dewa Ayu Citra , Kusmiyati Kusmiyati 
Published: September 2023

Protease enzymes are widely applied in the industrial field. Protease enzymes have high economic prospects with unmet demand. This article describes protease activity of two fungi isolated from avocados and from coconuts fleshes that previously have shown a high lipolytic activity on pH 7 to pH 10. The protease test was performed on PDA medium supplemented with 1% of skim milk, and adjusted to pH 7, pH 8 and pH 9 and was incubated at room temperature and at 30°C. Protease activity was determined based on the clear zone around the colony observed on day two – day eight. The results showed that variations in pH and temperature had a significant effect on the protease activity. The highest protease activity of isolate from avocado and from coconut fleshes were observed at pH 7, room temperature and incubated for 24 hours, with a protease activity index of 0.36 and 0.31 respectively.
EFEKTIVITAS PENANGGULANGAN TINDAK PIDANA PENCURIAN KENDARAAN BERMOTOR DI WILAYAH HUKUM POLSEK MATARAM
Authors: Nurhadhrami Rizvy Muhammad , Rodliyah Rodliyah , Ivan Natsir Nanda 
Published: September 2023

Penelitian ini bertujuan untuk menganalisis efektifitas penanggulangan tindak pidana pencurian kendaraan beromotor di wilayah hukum Polsek Mataram. Metode analisis data dalam penelitian ini adalah metode penelitian hukum empiris dan analisis kualitatif. Berdasarkan hasil penelitian efektivitas penanggulangan tindak pidana pencurian kendaraan bermotor di wilayah hukum Polsek Mataram, upaya penangulangan yang dilakukan oleh Kepolisian sektor Mataram dengan melakukan patroli, memberikan himbauan dan kerjasama dngan lembaga masyarakat,melakukan penyelidikan dan penyidikan serta razia sehingga upaya dapat dikatakan cukup efektif. Hal ini dapat dilihat dari jumlah laporan kasus yang masuk sejak 2021 hingga 2022 mengalami penurunan kasus