bluuebunny/crossref_metadata_2025_split huggingface dataset:
PPDONet: Deep Operator Networks for Fast Prediction of Steady-state Solutions in Disk–Planet Systems
Authors: Mao 毛 Shunyuan 顺元 , Dong 董 Ruobing 若冰 , Lu Lu , Yi Kwang Moo , Wang Sifan , Perdikaris Paris 
Published: June 2023

Abstract
We develop a tool, which we name Protoplanetary Disk Operator Network (PPDONet), that can predict the solution of disk–planet interactions in protoplanetary disks in real time. We base our tool on Deep Operator Networks, a class of neural networks capable of learning nonlinear operators to represent deterministic and stochastic differential equations. With PPDONet we map three scalar parameters in a disk–planet system—the Shakura–Sunyaev viscosity α, the disk aspect ratio h
0, and the planet–star mass ratio q—to steady-state solutions of the disk surface density, radial velocity, and azimuthal velocity. We demonstrate the accuracy of the PPDONet solutions using a comprehensive set of tests. Our tool is able to predict the outcome of disk–planet interaction for one system in less than a second on a laptop. A public implementation of PPDONet is available at https://github.com/smao-astro/PPDONet.
La relation de service face à un « double bénéficiaire » : l’exemple du travail dans les EHPAD ?
Authors: Devetter François-Xavier , Dussuet Annie , Nirello Laura , Puissant Emmanuelle 
Published: June 2023

La relation de service dans les métiers du « prendre soin » est complexe, notamment en raison de la dualité des bénéficiaires : le service s’adresse en effet d’abord aux personnes vulnérables mais également à leur entourage. Cet article vise à questionner, à partir du rôle des « familles » dans les EHPAD, leur impact sur les conditions de travail des intervenantes et les conditions à mettre en place pour que la coopération puisse exister entre proches et professionnelles.
Load distribution in flat reciprocal structures
Authors: Gonzalo Calderón Laura , Aira Zunzunegui José Ramón 
Published: June 2023

The elements in conventional structures are perfectly ranked, so that load transmission is logical and follows the usual structural orders. Nevertheless, in reciprocal structures each element has to support all of the others in a less intuitive pattern of load transmission. The purpose of this paper is to understand exactly how load is transmitted between elements, quantifying this analytically by developing a new method which is applicable to a flat structure composed of a basic unit with any number of nexors. It is based on determining the increase in load to which the members in a reciprocal structure are subjected by calculating the coefficient k, or “transference coefficient”. The k coefficient value, and therefore the load transferred between members, falls with the number of nexors, with the proximity of point loads to exterior supports, and with the size of the central space in the structure.
De « l’impuissance nerveuse » à « l’impuissance psychique »
Authors: Walin Marie 
Published: June 2023

Cet article explore des diagnostics établis entre les années 1840 et 1910 par des médecins espagnols, attribuant une impuissance sexuelle masculine à des problèmes qualifiés de « moraux » ou « nerveux ». Il est fondé sur l’étude de trente-six causes de nullité de mariage pour impuissance sexuelle, instruites par les tribunaux diocésains de Madrid et de Saragosse ; de vingt-deux articles portant sur l’impuissance sexuelle publiés dans les deux principales revues médicales espagnoles ; ainsi que sur un corpus de dictionnaires et d’essais médicaux traitant de la santé sexuelle. L’objectif est de montrer comment ces causes non physiques étaient intégrées dans des schémas de pensée rationnels mettant en jeu les savoirs de l’époque sur le cerveau et le système nerveux. L’article montre que, malgré la prégnance de croyances qui attribuent « l’affaiblissement nerveux » à des pratiques sexuelles répréhensibles, la fin du xixe siècle voit l’émergence d’une approche psychologique des troubles de l’érection.
Troubles dans la masculinité
Authors: Le Bras Anatole 
Published: June 2023

Cet article examine les liens entre folie, internement et masculinités dans la seconde moitié du xixe siècle en se fondant sur les archives de trois asiles d’aliénés situés à Quimper, Morlaix et Ville-Évrard. Allant à l’encontre de l’idée répandue d’un surenfermement asilaire des femmes au xixe siècle, il commence par mettre en évidence la nette surreprésentation des hommes dans les statistiques d’admission. L’article examine ensuite les spécificités de la folie masculine, et montre la place centrale qu’y occupent l’alcoolisme et les comportements violents. Ainsi, loin d’être associée à une forme d’effémination ou de démasculinisation, l’aliénation mentale a bien plus souvent à voir avec une forme d’exagération ou d’exacerbation pathologique de la virilité. En régulant ainsi ses excès, l’internement asilaire a pu contribuer à l’avènement d’une masculinité « apaisée » (Anne-Marie Sohn).
Tra folli e degenerati
Authors: Zecca Nemola Chiara 
Published: June 2023

L’article analyse les raisons qui ont amené la psychiatrie au centre du débat médical et politique dans les milieux militaires italiens à la fin du xixe siècle. Une attention particulière a été accordée à la catégorie nosologique de la folie morale, dans le but de montrer le rôle joué par la médecine militaire dans la construction d’une définition de la masculinité normée. Pour appréhender l’adhésion de la psychiatrie à une représentation polarisée de l’identité sexuelle, on a eu recours à des sources écrites par deux des premiers aliénistes de l’époque, Pietro Brancaleone-Ribaudo et Filippo Saporito. Pour ce qui est de Brancaleone-Ribaudo, nous avons examiné les méthodes anamnestiques qu’il présente dans son essai pionnier Studio antropologico del militare delinquente (Étude anthropologique du soldat délinquant, 1894). En ce qui concerne Saporito, nous avons analysé certains de ses diagnostics effectués sur des soldats enfermés dans le secteur pénitentiaire de l’hôpital psychiatrique d’Aversa, dont il est question dans son essai Sulla delinquenza e sulla pazzia dei militari (Sur la délinquance et la folie des soldats), paru en 1903.
Succès et déclin d’un agent thérapeutique : la sangsue
Authors: Sueur Nicolas 
Published: June 2023

Le propos de cet article est de s’interroger sur ce qui contribue au succès de certains remèdes à un moment donné. Les sangsues constituent à cet égard un exemple intéressant. Elles suscitent en effet un véritable engouement du public dans la première moitié du xixe siècle. Pour certains historiens, ce succès tient au manque de chirurgiens pour pratiquer la saignée et au succès des théories de François Broussais. Sans nier ces deux éléments, nous montrons que l’usage de la sangsue témoigne aussi de la persistance des théories humorales et du maintien de la saignée. Néanmoins, le recours massif aux sangsues s’explique par les doutes qui gagnent certains médecins quant aux vertus des saignées générales. Appliquées à certains endroits, elles présentent aussi l’avantage d’être faciles d’utilisation. Enfin, il ne faut pas négliger le rôle des malades, qui craignent moins les sangsues que la saignée générale. Cette demande de sangsues stimule le secteur de l’hirudoculture et suscite l’intérêt de l’État. En résumé, la sangsue apparaît comme un « remède de transition » qui accompagne le lent déclin de la saignée et de la médecine des humeurs.
Dire les traumas de la deuxième génération : le film d’animation “Les secrets de mon père”
Authors: Graceffa Agnès 
Published: June 2023

FILM D’ANIMATION : Comment grandir avec un père rescapé des camps ? C’est la douloureuse question qu’illustre avec finesse le dessin animé très touchant, Les Secrets de mon père, sorti en salle en septembre 2022, et dont le scénario s’inspire très librement du roman graphique de Michel Kichka Deuxième génération. Ce que je n’ai pas dit à mon père (Dargaud, 2012), fils du survivant des camps Henri Kichka.
“Les anges d’Auschwitz” Stephen Desberg – Emilio van der Zuiden
Authors: Crahay Frédéric 
Published: June 2023

BD : Hiver 1929. La vie s’écoule paisiblement dans une ville polonaise semblable à Lodz ou Varsovie. Un gamin regarde tomber la neige ; il prie les anges de lui ramener son père, qu’il aimerait tant serrer à nouveau dans ses bras. Son vœu est exaucé, car son père revient le lendemain. À partir de cet instant, ce jeune garçon de huit ans est certain que les anges vivent parmi nous… Cette famille heureuse est loin de se douter que cette quiétude ne durera plus longtemps. En 1939, l’Allemagne envahit la Pologne, et la Seconde Guerre mondiale éclate. Les Juifs sont conduits dans le ghetto, première étape avant les camps. Dans ce nouveau monde d’effroi, l’horreur porte à présent un nom : Auschwitz. Comment survivre face à la barbarie, à l’indicible, au pire… En priant les anges ?
Survivre, Témoigner, Transmettre : Parcours et récits de femmes survivantes de la Shoah en Grèce
Authors: Varon-Vassard Odette 
Published: June 2023

Dans le corpus des témoignages de Juifs grecs, on compte sur les doigts d’une main les femmes qui ont réussi à casser leur silence. Odette Varon-Vassard s'intéresse dans cet article aux témoignages de Lisa Mano-Pinhas, de Berry Cassouto-Nahmias, d'Erika Kounio-Amariglio, et de Nata Osmo-Gattegno.
Eos Promotes TH2 Differentiation by Interacting with and Propagating the Activity of STAT5
Authors: Tuazon Jasmine A , Read Kaitlin A , Sreekumar Bharath K , Roettger Jack E , Yaeger Michael J , Varikuti Sanjay , Pokhrel Srijana , Jones Devin M , Warren Robert T , Powell Michael D , Rasheed Mustafa N , Duncan Elizabeth G , Childs Lauren M , Gowdy Kymberly M , Oestreich Kenneth J 
Published: June 2023

Abstract
The Ikaros zinc-finger transcription factor Eos has largely been associated with sustaining the immunosuppressive functions of regulatory T cells. Paradoxically, Eos has more recently been implicated in promoting proinflammatory responses in the dysregulated setting of autoimmunity. However, the precise role of Eos in regulating the differentiation and function of effector CD4+ T cell subsets remains unclear. In this study, we find that Eos is a positive regulator of the differentiation of murine CD4+ TH2 cells, an effector population that has been implicated in both immunity against helminthic parasites and the induction of allergic asthma. Using murine in vitro TH2 polarization and an in vivo house dust mite asthma model, we find that EosKO T cells exhibit reduced expression of key TH2 transcription factors, effector cytokines, and cytokine receptors. Mechanistically, we find that the IL-2/STAT5 axis and its downstream TH2 gene targets are one of the most significantly downregulated pathways in Eos-deficient cells. Consistent with these observations, we find that Eos forms, to our knowledge, a novel complex with and supports the tyrosine phosphorylation of STAT5. Collectively, these data define a regulatory mechanism whereby Eos propagates STAT5 activity to facilitate TH2 cell differentiation.
Recurrence Rate of High-altitude Pulmonary Edema in Lowlanders Inducted Temporarily to High-altitude Areas
Authors: Pandey I. M. , Choudhary Robin , Vasan Amit Singh , Chopra Manu , Sharma Anmol 
Published: June 2023

Abstract

Background:
Some section of the Indian population resides in high-altitude areas of the mighty Himalayas. In addition to the residents who inhabit mountainous areas, there is also a group of lowlanders who occasionally visit these regions temporarily for work-related purposes or vacations. These individuals are prone to high-altitude illnesses, including acute mountain sickness and high-altitude pulmonary edema (HAPE). This cohort study was undertaken, among acclimatized and nonacclimatized lowlanders based on 3 years of data at a tertiary care hospital, to study the recurrence rate of HAPE in lowlanders.

Materials and Methods:
The inception cohort consisted of consecutive cases of HAPE among lowlanders, temporarily posted to these high-altitude regions, over 3 years. This cohort was followed up for at least 1 year. The recurrence rate of HAPE in terms of incidence density in person-months and cumulative incidence was calculated, and variables, including clinical features, altitudes at which the symptoms occurred, mode of induction to the high-altitude area, and time of onset of HAPE episodes postinduction altitudes, were studied.

Results:
The study revealed the recurrence of HAPE as an incidence density of 88.7 per 1000 person-months (95% confidence limit 66.1–115.9 per 1000 person-months). The cumulative incidence was 125 per 1000, over an average follow-up of 22.54 months (95% confidence limit 26–323 per 1000). The study revealed that the recurrence was found to occur at similar altitudes as the previous episode even after following strict acclimatization protocols and slow induction to the high-altitude area by road route with the onset of symptoms within 72 h of entry into the high-altitude area.

Conclusion:
This study brought out that there is a risk of recurrence of HAPE in lowlanders temporarily inducted to high-altitude areas, with previous episodes of HAPE at similar altitudes as previous episodes, even when acclimatization protocols are followed.
Epidural catheter migration in non-obstetric adult surgical patients: A prospective, observational, cohort study
Authors: Jose Riya , Greenlin Latha , Isac Divya , Yadav Bijesh , Joselyn Anita Shirley 
Published: June 2023

Background and Aims:
Epidural catheter migration is a well-described complication in the obstetric population, though its significance in the non-obstetric surgical population is not known. The purpose of this study was to explore the incidence of epidural catheter migration in a non-obstetric adult surgical cohort, assess the factors associated with migration and analyse complications among patients with and without catheter migration.

Methods:
In this single-centre, prospective, observational study, the acute pain services team collected data over 12 months on consecutive, adult non-obstetric surgical patients who received an epidural catheter for postoperative pain management. Details of epidural catheter insertion, fixation, migration and complications were collected from the first to the fourth postoperative day.

Results:
Of the 510 patients recruited, epidural catheter migration was noted in 233 patients (45.7%), of which 152 (65.2%) migrated outwards and the rest migrated inwards. Also, 72 (30.9%) and 86 (31.05%) complications were noted in the groups with and without catheter migration, respectively. The most frequent complications noted were inadequate analgesia, unilateral sensory block, motor block and hypotension in both groups. We did not find any correlation between the frequency of epidural catheter migration and demographic factors.

Conclusions:
Epidural catheter migration is a sizeable postoperative occurrence in non-obstetric surgical patients. Factors that might play a role in catheter migration could not be established in this study. There is an almost similar frequency of complications noted among patients with and without catheter migration, with the most common being inadequate analgesia in both groups.
Refractive profile of children treated with intravitreal bevacizumab for retinopathy of prematurity
Authors: Pawar Neelam , Somyashree D , Meenakshi R , Maheshwari Devendra , Mohideen Syed , Uduman Mohammed Sithiq 
Published: June 2023

Purpose:
To study the refractive profile of children after they received intravitreal injection of bevacizumab for retinopathy of prematurity (ROP).

Methods:
The study was conducted at a tertiary eye care hospital in South India. ROP patients of more than 1 year of age, presenting to the Pediatric Ophthalmology Clinic and Retina Clinic and having history of treatment for type I ROP with intravitreal bevacizumab (IVB) or intravitreal bevacizumab and laser photocoagulation were included in the study. Cycloplegic refraction was done, and the refractive status was evaluated. The refractive status of age-matched, full-term children with uneventful perinatal and neonatal history was also recorded and compared to the study group.

Results:
Among 134 eyes of 67 study subjects, the major refractive error was myopia in 93 eyes (69.4%; spherical equivalent [SE] = −2.89 ± 3.1, range = −11.5 to −0.5 D). There were 75 eyes (56%) with low-to-moderate myopia; high myopia was seen in 13.4%, emmetropia in 18.7%, and hypermetropia in 11.9% of eyes. The majority of them (87%) had with-the-rule (WTR) astigmatism. In 134 eyes, the SE was −1.78 ± 3.2 (range = −11.5 to 4 D); the SE of the 75 eyes with low-to-moderate myopia was −1.53 ± 1.2 (range = −0.50 to −5 D). In the control group, the majority had emmetropia (91.8%). There was no significant association between the age at which IVB had been injected and the development of refractive errors (P = 0.078). The prevalence of low-to-moderate myopia was more than high myopia in patients with zone I and zone II ROP before treatment (60.0% and 54.5%, respectively).

Conclusion:
Myopia was the major refractive error seen in post-IVB pediatric patients. WTR astigmatism was more commonly seen. The age at which IVB injection had been given had no effect on the development of refractive errors.
Impact of a formal manual small-incision cataract surgery curriculum in an American ophthalmology residency program
Authors: Ifantides Cristos , SooHoo Jeffrey R , Christopher Karen L 
Published: June 2023

Purpose:
Global ophthalmology educational activities often include the ability of ophthalmology residents to partake in low-resource clinical care at home and abroad. Low-resource surgical techniques have become a pillar of education during formalized global ophthalmology fellowships. A formal manual small-incision cataract surgery (MSICS) curriculum was started in the University of Colorado’s residency training program to meet the growing demand for this surgical skill and to allow for more sustainable outreach work from our graduates. The survey was conducted to collect evaluations on the value of formal MSICS training within a United States–based residency program.

Methods:
This was a survey study in a US ophthalmology residency program. A formal MSICS curriculum was created that included didactic lectures on epidemiology of global blindness, MSICS technique, and how MISCS compared to phacoemulsification in terms of cost and sustainability in low-resource settings, followed by a formal wet lab experience. Residents were then exposed to MSICS procedures in the operating room (OR) under supervision of an experienced MSICS surgeon. An anonymous online survey was conducted on three consecutive cohorts of recently graduated senior ophthalmology residents from 2019 to 2021 with the aim of eliciting opinions about and outcomes from the new curriculum.

Results:
Fifteen graduating senior residents comprised the three cohorts with a 100% survey response rate. All residents agreed or strongly agreed that “MSICS is a valuable skill to have”. Eighty percent of respondents agreed or strongly agreed that “exposure to MSICS has increased my likelihood of doing any type of outreach work in the future” and 86.67% agreed or strongly agreed that “exposure to MSICS increased my understanding about sustainable outreach work”. The average number of cases assisted or performed per resident was 8.2 (SD 2.7, range 4–12).

Conclusion:
A formal MSICS curriculum for US-based ophthalmology residents was well-received by the trainees. The majority felt it increased their likelihood of pursuing and improved their understanding of sustainable outreach work. The curriculum, which included lectures, wet lab training, and formal teaching in the OR, could add value to a residency program’s curriculum. Furthermore, a formal domestic program can avoid ethical pitfalls that can be seen with resident teaching during international mission work.
Correlation between different retinal layers with visual acuity in diabetic retinopathy patients with clinically significant macular edema
Authors: Parveen Shama , Mishra Deepak , Gurnani Bharat , Kaur Kirandeep , Ziada Hossameldin A , Srivastav Tanmay , Bhushan Prashant 
Published: June 2023

Purpose:
To study the corelation between outer retinal layer thickness (ORL), outer photoreceptor segment thickness (PROS), and central macular thickness (CMT) with best-corrected visual acuity (BCVA) in patients having clinically significant macular edema (CSME) and compare these parameters with normal patients.

Methods:
This was a prospective, nonrandomized, observational, comparative study done during the period of January to May 2019. The study included 60 eyes of 36 patients. The patient population was segregated into two Groups: Group I (30 normal eyes of 15 normal patients) and Group II (30 eyes of 21 diabetic patients) with CSME. The comparison between ORL, PROS, and CMT was made between both the groups, and the correlation between ORL thickness, PROS thickness, and CMT with BCVA in Group II was studied.

Results:
The mean age in Group I was 52.6+10.66 years, and 53.42+8.15 years in Group II. The male/female ratio was 1.1:1 in Group I and 4:3 in Group II. The mean CMT was greater in Group II (330.13 ± 37.01) than in Group I (222.20 ± 12.30). The mean ORL thickness was greater in Group I (97.73 ± 6.92) than in Group II (80.63 ± 9.03). The PROS thickness was statistically significant in Group I (35.05 ± 3.4) than in Group II (28.57 ± 3.53). There was a strong correlation between BCVA and ORL thickness (r = −0.580, P < 0.001) and more strong correlation between BCVA and PROS thickness in Group II (r = −0.611, P < 0.000). There was a moderate correlation between BCVA and CMT (r = 0.410, P < 0.025), and all results were statistically significant.

Conclusion:
Both ORL and PROS thickness were greater in healthy normal eyes than in eyes with CSME. BCVA was strongly correlated with PROS and ORL thickness and moderately associated with CMT.
Compliance with follow-up in patients with diabetic macular edema: Eye care center vs. diabetes care center
Authors: Kumar Geetha , Velu Saranya , Rajalakshmi Ramachandran , Surya Janani , Mohan Viswanathan , Raman Aayushi , Raman Rajiv 
Published: June 2023

Purpose:
The study was conducted to compare the compliance to intravitreal injection treatment and follow-up in patients with center-involving diabetic macular edema (CI-DME) and treatment outcomes between a tertiary eye care facility and a tertiary diabetes care center.

Methods:
A retrospective review was conducted on treatment naïve DME patients who had received intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections in 2019. Participants were people with type 2 diabetes who were under regular care at the eye care center or the diabetes care center in Chennai. The outcome measures were noted at months 1, 2, 3, 6, and 12.

Results:
A review of 136 patients treated for CI-DME (72 from the eye care center and 64 from a diabetes care center) was carried out. The severity of diabetic retinopathy (DR) was similar in both centers. There was no statistically significant (P > 0.05) difference in the choice of initial intravitreal drug in the two centers. At 12-month follow-up, only 29.16% came for a follow-up in the eye center vs. 76.56% in a diabetes care center (P = 0.000). The multivariate logistic regression showed increasing age was associated with non-compliance in both the groups (eye care center: odds ratio [OR] 0.91; 95% confidence interval [CI] 0.82–1.21; P = 0.044) and diabetes care center (OR 1.15; 95% CI 1.02–1.29; P = 0.020).

Conclusion:
The follow-up rate between eye care and diabetic care center with DME showed a significant disparity. By providing comprehensive diabetes care for all complications under one roof, compliance with follow-up can be improved in people with DME.