bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kneeling tolerance when using quadriceps tendon autograft for anterior cruciate ligament reconstruction is superior to hamstring tendon autograft
Authors: Calvert Nicholas D. , Ebert Jay R. , Radic Ross 
Published: January 2025

AbstractPurposeTo investigate kneeling tolerance in patients undergoing hamstring (HT) versus quadriceps (QT) anterior cruciate ligament reconstruction (ACLR) and investigate correlation with patient‐reported outcome measures (PROMs).MethodsAfter recruitment and randomisation, 112 patients (HT = 55; QT = 57) underwent ACLR. Patients were assessed at 6, 12 and 24 months using the Kneeling Tolerance Test, which evaluates patient‐reported pain in a position of both 90 (KT90) and 110 (KT110) degrees of knee flexion. PROMs collected included the International Knee Documentation Committee (IKDC) questionnaire and the ACL Return to Sport after Injury (ACL‐RSI) questionnaire.ResultsKneeling tolerance at KT90 and KT110 improved (p < 0.05) for both graft types across all time points. There was no difference in KT90 scores between groups at 6 or 12 months. At 24 months, kneeling tolerance was superior in the QT group (mean HT 93 ± 9 vs. QT 98 ± 5; p = 0.003). For KT110 scores, a statistically significant difference was noted at 6 (mean HT 80 ± 25 vs. QT 89 ± 12; p = 0.027), 12 (mean HT 90 ± 13 vs. QT 95 ± 10; p = 0.040) and 24 months (mean HT 92 ± 10 vs. QT 97 ± 5; p = 0.003). The ACL‐RSI was significantly correlated with KT90 and KT110 at 24 months (r = 0.40, p < 0.001; r = 0.40, p < 0.001). Other PROMs demonstrated significant weak‐to‐moderate correlations with kneeling tolerance.ConclusionPatients undergoing ACLR with a QT versus HT autograft report superior kneeling tolerance up to 2 years postsurgery, more prominent in deeper (110°) knee flexion. A strong correlation with ACL‐RSI was demonstrated at 2 years.RegistrationACTRN12618001520224p (Australian New Zealand Clinical Trials Registry).Level of EvidenceLevel 1.
Photonic Terahertz Chaos Enabling High‐Precision and Unambiguous Ranging
Authors: Deng Qiuzhuo , Zhang Lu , Yang Zuomin , Lyu Zhidong , Bobrovs Vjaceslavs , Pang Xiaodan , Ozolins Oskars , Yu Xianbin 
Published: January 2025

AbstractTerahertz (THz, 0.3–10 THz) radar systems have garnered significant attention due to their superior capabilities in high‐precision and robust sensing. However, the susceptibility to jamming, along with the sensing precision loss and ranging ambiguity induced by inflexible implementation of the conventional radar signal source, presents major challenges to the practical deployment of THz radars. Herein, a flexible photonic chaotic radar system is proposed at the THz band and investigate the ranging performance in precision and ambiguity. The photonic heterodyne detection scheme facilitates the generation of optoelectronic feedback loop‐based THz chaos at 300 GHz, achieving a seamless connection between THz domains and optical domains. The system is experimentally demonstrated its superior performance of sub‐centimeter resolution with 0.9345 cm and ranging unambiguity simultaneously. This work bridges the THz gap in the practical deployment of chaos theory and will pave the way for a new regime of THz radar empowered by chaos.
Polarization‐Locked Floquet Higher‐Order Topological Insulators in Synthetic Dimension
Authors: Liu Zhuoxiong , Liu Weiwei , Zheng Lingzhi , Ren Shuaifei , Su Xiaolong , Ding Yufan , Wang Bing , Lu Peixiang 
Published: January 2025

AbstractFloquet engineering provides a powerful tool for exploring topological physics. Systems incorporating Floquet driving can exhibit intriguing topological phenomena without correspondence with static counterparts. Recently, following the development of higher‐order topology, Floquet higher‐order topological insulators have drawn great attention since its peculiarity in the band structure and topological states. Here the higher‐order topological insulator is theoretically demonstrated via Floquet engineering in synthetic frequency dimension. To this end, a 1D Floquet topological insulator is first constructed by introducing periodic driving to the frequency lattice, and the corresponding 0 and π edge states are demonstrated. On this basis, a Floquet higher‐order topological insulator supporting 0 and π corner states is realized by stacking the chains of the 1D Floquet topological insulators with dimerized couplings. Particularly, it is found that the distributions of 0 and π modes occupy the frequency lattices with orthogonal polarizations, which indicate polarization‐locked topological states and enable selective excitation of the topological edge/corner states with specific polarizations. This work lays the foundation for realizing controllable Floquet systems and opens an avenue for exploring higher‐order topological physics with synthetic dimension, which shows great promise for applications in polarization conversion and quantum information processing.
Second Harmonic Generation with 48% Conversion Efficiency from Cavity Polygon Modes in a Monocrystalline Lithium Niobate Microdisk Resonator
Authors: Sun Chao , Ni Jielei , Li Chuntao , Lin Jintian , Gao Renhong , Guan Jianglin , Qiao Qian , Hou Qifeng , Luo Xiaochao , Zheng Xinzhi , Qiao Lingling , Wang Min , Cheng Ya 
Published: January 2025

AbstractThin‐film lithium niobate (TFLN) based optical microresonators offer large nonlinear coefficient d33 and high light‐field confinement, allowing highly efficient second‐order optical nonlinear frequency conversion. Here, ultra‐efficiency SHG from high‐Q polygon modes is achieved by maximizing the utilization of the highest nonlinear coefficient d33 in a monocrystalline X‐cut TFLN microdisk resonator for the first time. The polygon modes are designed and formed with two parallel sides perpendicular to the optical axis of the lithium niobate crystal by introducing weak perturbations into the microdisk through a tapered fiber, which maximizes the utilization of d33. The polygon modes exhibit ultrahigh intrinsic Q factors up to 3.86 × 107, due to the fact that polygon modes are located far from the relatively rough sidewall of the microdisk. Moreover, the pump and second harmonic polygon modes share high modal overlap factor of ≈80%. Consequently, SHG from cavity polygon modes with absolute conversion efficiency as high as 48.08% is realized at an on‐chip pump level of only 4.60 mW without fine domain structures, surpassing the best results (23% and 30%) reported in other two domain‐inversion‐free phase matching schemes and even approaching the record (52%) in periodically poled TFLN microresonators.
Xanthium‐Inspired Microsphere Morphology Depends on the Dual Self‐Assembly Behavior of Macromolecules
Authors: Xing Luyao , Ding Jiaqiang , Gao Jiaqi , Chen Dongliang , Xiong Chengdong , Xiong Zuochun 
Published: January 2025

AbstractThe self‐assembly of macromolecular segments promotes the fabrication of polymer microspheres with multiple morphologies. Inspired by the xanthium shells, A dual‐driven self‐assembly method have defined that enables the construction of multi‐dimensional morphologies on the microsphere surface at emulsion‐confined interfaces. The two driving forces are derived from the phase separation caused by the immiscibility of macromolecular segments and the different interactions between chain segments of different hydrophilicity and water molecules. The synergistic effects of these two forces, the xanthium shell structure is constructed on the microsphere surface, enabling the development of increasingly complex superstructure. This scalable approach provides extensive potential for the self‐assembly technology of block copolymers with opposite properties.
H3K14la drives endothelial dysfunction in sepsis‐induced ARDS by promoting SLC40A1/transferrin‐mediated ferroptosis
Authors: Gong Fangchen , Zheng Xiangtao , Xu Wen , Xie Rongli , Liu Wenbin , Pei Lei , Zhong Ming , Shi Wen , Qu Hongping , Mao Enqiang , Yang Zhitao , Li Ranran , Chen Erzhen , Chen Ying 
Published: January 2025

AbstractPulmonary endothelial cell (EC) activation is a key factor in acute respiratory distress syndrome (ARDS). In sepsis, increased glycolysis leads to lactate buildup, which induces lysine lactylation (Kla) on histones and other proteins. However, the role of protein lactylation in EC dysfunction during sepsis‐induced ARDS remains unclear. Integrative lactylome and proteome analyses were performed to identify the global lactylome profile in the lung tissues of septic mice. Cut&Tag analysis was used to identify the transcriptional targets of histone H3 lysine 14 lactylation (H3K14la) in ECs. Septic mice presented elevated levels of lactate and H3K14la in lung tissues, particularly in pulmonary ECs. Suppressing glycolysis reduced both H3K14la and EC activation, suggesting a link between glycolysis and lactylation. Moreover, H3K14la was enriched at promoter regions of ferroptosis‐related genes such as transferrin receptor (TFRC) and solute carrier family 40 member 1 (SLC40A1), which contributed to EC activation and lung injury under septic conditions. For the first time, we reported the role of lactate‐dependent H3K14 lactylation in regulating EC ferroptosis to promote vascular dysfunction during sepsis‐induced lung injury. Our findings suggest that manipulation of the glycolysis/H3K14la/ferroptosis axis may provide novel therapeutic approaches for sepsis‐associated ARDS.
New Multiomic Studies Shed Light on Cellular Diversity and Neuronal Susceptibility in Parkinson's Disease
Authors: Liang Marianna , Chu Linh , Yue Zhenyu 
Published: January 2025

AbstractParkinson's disease is a complex neurodegenerative disorder characterized by degeneration of dopaminergic neurons, with patients manifesting varying motor and nonmotor symptoms. Previous studies using single‐cell RNA sequencing in rodent models and humans have identified distinct heterogeneity of neurons and glial cells with differential vulnerability. Recent studies have increasingly leveraged multiomics approaches, including spatial transcriptomics, epigenomics, and proteomics, in the study of Parkinson's disease, providing new insights into pathogenic mechanisms. Continued advancements in experimental technologies and sophisticated computational tools will be essential in uncovering a network of neuronal vulnerability and prioritizing disease modifiers for novel therapeutics development. © 2025 International Parkinson and Movement Disorder Society.
Stabilization for Coupled Hyperbolic System With Memory Effects Via Minimal State Variable
Authors: Lv Mengxian , Wang Junmin 
Published: January 2025

ABSTRACTIn this work, we investigate the stabilization of a coupled PDE's system consisting of one Kirchhoff plate and one wave equation with memory effects. Three different cases are considered where the frictional infinite memory occurs in both equations or in one of the equations. First, we achieve the existence and uniqueness of the solution, utilizing the concept of minimal state variable. Moreover, it is shown that the coupled system is forced to polynomially decay. And by frequency domain analysis, the explicit decay rates are established, which only depend on the place of memory effect.
The Relationship Between Fibromyalgianess and Clinical Features, Disease Activity in Patients With Systemic Lupus Erythematosus
Authors: Varman Büşra , Parlak Selman , Ecesoy Hilal 
Published: January 2025

ABSTRACTIntroductionFibromyalgia (FM) is a chronic syndrome characterised by widespread pain, fatigue, and symptoms such as sleep disturbances, cognitive impairment, and mood disorders. FM prevalence is notably higher among systemic lupus erythematosus (SLE) patients compared with the general population, often leading to diagnostic challenges. Misinterpreting FM as SLE activity can result in overtreatment. This study aimed to evaluate fibromyalgianess and its relationship with the clinical and immunological characteristics of SLE patients using comprehensive scoring methods for better diagnostic accuracy.Materials and MethodsThis cross‐sectional study included 50 SLE patients meeting the 2019 EULAR/ACR classification criteria. Patients with coexisting autoimmune diseases or severe systemic conditions were excluded. Clinical data, SLEDAI scores, and fibromyalgianess severity were assessed using the Polysymptomatic Distress Scale (PSDS). Patients were categorised into groups based on fibromyalgia diagnostic criteria: widespread pain and SLE‐FM. Statistical analysis was performed using SPSS, with p < 0.05 considered significant.ResultsAmong 50 patients (45 female, 5 male; mean age 42.04 ± 12.5), 24% had fibromyalgianess, and 18% experienced widespread pain. Female patients exhibited significantly higher PSDS scores (p < 0.05). While NSAID use was associated with increased PSDS scores (p < 0.001), no significant relationship was found between fibromyalgianess and SLEDAI scores or organ involvement.ConclusionFibromyalgianess in SLE patients primarily reflects heightened pain sensitivity and symptom severity rather than disease activity. Incorporating fibromyalgianess assessment into routine SLE management may prevent diagnostic and therapeutic pitfalls and improve treatment outcomes. Multidisciplinary approaches, including pharmacological and non‐pharmacological strategies, are essential for effective care.
Behavioral and Electrophysiological Assessment of Central Auditory Processing in Individuals with Sickle Cell Disease
Authors: Lopes Rhayane Vitória , Braga Josefina Aparecida Pellegrini , Angel Andrea , Gil Daniela 
Published: January 2025

ABSTRACTIntroductionSickle cell anemia has a genetic origin characterized by an autosomal recessive inheritance pattern. The nervous system may be subject to vaso‐occlusion and, consequently, affect the proper functioning of the central portion of hearing.ObjectiveTo assess central auditory skills and analyze short‐ and long‐latency auditory evoked potentials in children with sickle cell disease.MethodsCross‐sectional study. All children had normal hearing thresholds, and their central auditory processing underwent behavioral assessment with a battery of tests involving dichotic and monotic listening, binaural interaction, and temporal processing. The electrophysiological assessment used short‐ and long‐latency auditory evoked potentials. Descriptive statistics were performed.ResultsOf the 28 subjects evaluated (mean age of 9.46 years), 18 were females and 10 were males. Central auditory processing disorder was identified in 85.7% of the children. The auditory skills of figure‐ground for verbal sounds, binaural interaction, and complex temporal ordering were the most affected. An increase in the absolute latencies of Waves III and V was observed in the short‐latency potential.ConclusionIndividuals with sickle cell disease have central auditory processing disorder, identified primarily by behavioral assessment.
The impact of matrix viscosity on the mechanical behavior of fiber reinforced composites
Authors: Zhao Ke , You Geyi , Gao Xiaoping , Jiang Xin , Chen Miao , Liu Chengwei , Chen Xinya , An Lan , Du Peijian 
Published: January 2025

AbstractThe influence of matrix viscosity on the mechanical behavior of fiber reinforced composites was investigated in this paper. The glass fiber fabric was selected as reinforcement and the mixed solution composed of resin, curing agent and different viscosity of diluent was selected as matrix. The composites was fabricated by vacuum‐assisted resin infusion (VARI). The influence of matrix viscosity on bending, impact and creep properties of composites were studied by varying the mass fraction of 1,4‐butanediol diglycidyl ether (BDDGE) diluent, the least square fitting was used to fit the experimental result. The mathematical model for characterizing the relationship between the matrix viscosity and the bending strength was established, and the mass fraction of BDDGE diluent based on the optimal bending property was obtained. The failure mechanisms were analyzed by analyzing fiber reinforced composites properties, reaction principles and fracture morphologies. Result shows that the epoxy groups within the viscosity undergo a ring‐opening reaction to integrate the cross‐linking network structure of the epoxy resin. However, an excessive amount of diluent will result in an increase of number of flexible chain segments, which initially enhancing the mechanical properties of the specimens before causing a subsequent decline. The mathematical model was substantiated by experiment, which reveals that the viscosity is 185.3 mPa·s for the optimal bending properties.Highlights
The bending strength and modulus reached the maximum at a viscosity of 180 mPa·s
The creep curves demonstrate progressive damage and minute deformation.
The ring‐opening reaction occurs with two oxygen atoms in the diluent BDDGE.
The matrix viscosity of BDDGE diluent is 185.3 mPa·s for the optimal bending properties.
Evaluating the structural parameter on the forming quality and tensile property of CFRP bolted joints with one‐sided connected rivet nut
Authors: Wang Jian , Liu Jintong , Zhu Chunrun , Zhang Yongliang , Bi Yunbo 
Published: January 2025

AbstractAs a kind of one‐sided connected rivet nut, the elliptical‐head non‐lug self‐locking (EHNL) rivet nut can ensure the gap‐free connection and realize the long life and reliable assembly connection of the aircraft. In this paper, the effect of the countersink angle and hole diameter of the nut on the forming quality and static tensile property of the joint is systematically studied. The results show that the effect of the countersink angle on the residual stress and damage of the CFRP plate is caused by the special mechanism that the material is easy to flow to the short‐axis barrel wall area when the nut is formed, and is also affected by the layup. While the effect of hole diameter on the residual stress and damage of CFRP plate is determined by the different deformation behavior of the rivet nut. As for the static tensile strength, the effect of the countersink angle is determined by the residual stress of the CFRP plate caused by the nut forming. But the effect of the hole diameter is small. Only when the hole diameter is 8.58 mm, the tensile strength is slightly reduced by 5.48% due to the large residual stress caused by the nut forming. Considering the forming quality and tensile property, the countersink angle of 45° and hole diameter of 8.46 mm are recommended for the specimen in this study.Highlights
Structural parameters on forming quality and tensile property is studied.
The influence mechanism on forming quality and tensile property is revealed.
Recommended values of structural parameters are provided.
Untargeted Characterization and Biological Activity of Amazonian Aqueous Stem Bark Extracts by Liquid and Gas Chromatography–Mass Spectrometry
Authors: Pastuña‐Fasso Jefferson V. , Espinosa de los Monteros‐Silva Nina , Quiroz‐Moreno Cristian Daniel , Medina‐Villamizar Evencio Joel , Sosa‐Pozo Gabriela , Cisneros‐Pérez Pablo A. , Proaño‐Bolaños Carolina , Radice Matteo , Niño‐Ruíz Zulay , Mogollón Noroska G. S. 
Published: January 2025

ABSTRACTIntroductionAqueous stem bark extracts of Aspidosperma rigidum Rusby, Couroupita guianensis Aubl., Monteverdia laevis (Reissek) Biral, and Protium sagotianum Marchand have been reported as traditional remedies in several countries of the Amazonian region. Despite previous research, further investigation to characterize secondary metabolites and the biological activity of extracts is needed to derive potential applications.Material and MethodsMetabolic profiling was carried out using liquid and gas chromatography coupled with mass spectrometry (UHPLC–MS/MS and GC–MS). The chemical composition of the studied plants was further compared by principal component analysis (PCA). Additionally, chemical profiles were correlated with antimicrobial and toxicity activities, which suggested potential metabolites for future research.ResultsWe identified 16 and 32 compounds by UHPLC–MS/MS and GC–MS analysis, respectively. Antimicrobial activity was detected in three stem bark extracts. C. guianensis showed inhibition of all tested microorganisms, including antibiotic‐resistant strains. Molecular networking approaches, in silico tools, and Pearson's correlation showed that antifungal compounds could be a terpene glycoside (r = 0.918) and/or a phenolic (r = 0.882) metabolite class.ConclusionThis study highlights the use of the established procedure in exploring the metabolomes of these species, which could be a novel source of antimicrobial drug discovery. Coupling the observed biological potential with UHPLC–MS/MS data has also accelerated the tracing of their bioactive compounds. These findings update the state of the art regarding the chemical composition and biological activity of the plant extracts, defining potential new applications for the pharmaceutical applications.
Preparation and Properties of Solid Propellant Adhesive System Based on Ethylene Vinyl Acetate/Wax Thermoplastic Elastomer
Authors: Hong Shih‐Ya , Wu Kuo‐Hui , Yeh Tsao‐Fa , Huang Wen‐Chien , Wang Je‐Chuang 
Published: January 2025

ABSTRACTIn this study, an ethylene vinyl acetate (EVA)/wax‐based thermoplastic propellant was prepared using a planetary mixer. High‐viscosity EVA was used as the thermoplastic elastomer, and either solid wax based on EVA oligomers or alternative liquid tributyl 2‐acetylcitrate (TBAC) were used as plasticizers to adjust its viscosity. This enhances the flow characteristics and reduces torque during the mixing process. Results: The addition of 30 wt.% wax significantly reduced the viscosity from 218.8 to 12.67 Pa s, whereas the addition of liquid TBAC did not lead to a significant reduction in the viscosity of EVA. Designed with different ratios of EVA/wax binder with a superior stress–strain relationship over polyurethane (PU). The EVA/wax‐based propellant has stable combustion characteristics at different combustion chamber pressures. St. Robert's Law provides an equation for the rate of combustion, and the performance parameters of the propellant derived from the internal ballistics simulation analysis are very valuable.
Electrospun nanofibers as controlled release systems for the combined pheromones of Grapholita molesta and Cydia pomonella
Authors: Xiang Hui‐Ming , Wei Xiao‐Hong , Li Yi‐Ran , Zhang Bo‐Jun , Li Min , Ma Rui‐Yan 
Published: January 2025

AbstractBACKGROUNDAs sex pheromones are environmentally friendly and specific, they are often used to monitor and control oriental fruit moths (OFMs). Currently, non‐biodegradable polymers are commonly employed as carriers to prepare controlled sex pheromone release systems for plant protection. Electrospinning is a relatively simple technique for preparing biodegradable nanofibers that allows for the controlled release of sex pheromones. This study aimed to develop a biodegradable controlled release system for the combination of OFM pheromone and codlemone via electrospinning, in which codlemone was used as a synergist for OFM pheromone.RESULTSNew systems for the controlled release of combined pheromones from OFM and colding moths were developed using electrospun nanofibers from polycaprolactone (PCL), cellulose acetate (CA), and polylactic acid (PLA). In the indoor experiments, the load ratio and release stability of CA nanofibers loaded with combined pheromones (CA‐SP) were superior to those of the other two nanofiber types. In the field experiments, among all the treatments, 10 mg of CA‐SP was the most attractive to OFMs, and its effective duration was approximately 6 weeks. The optimum storage temperature for all nanofibers was −20 °C.CONCLUSIONElectrospun CA‐SP nanofibers were biodegradable and environmentally friendly, with stable release. This study presents a new technique that could be beneficial for the monitoring and control of OFMs. © 2025 Society of Chemical Industry.