bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of thermo‐velocity barriers on fish: influence of water temperature, flow velocity and body size on the volitional swimming capacity of northern straight‐mouth nase (Pseudochondrostoma duriense)
Authors: García‐Vega Ana , Ruiz‐Legazpi Jorge , Fuentes‐Pérez Juan Francisco , Bravo‐Córdoba Francisco Javier , Sanz‐Ronda Francisco Javier 
Published: January 2023

AbstractWater temperature and flow velocity directly affect the fish swimming capacity, and thus, both variables influence the fish passage through river barriers. Nonetheless, their effects are usually disregarded in fishway engineering and management. This study aims to evaluate the volitional swimming capacity of the northern straight‐mouth nase (Pseudochondrostoma duriense), considering the possible effects of water temperature, flow velocity and body size. For this, the maximum distance, swim speed and fatigue time (FT) were studied in an outdoor open‐channel flume in the Duero River (Burgos, Spain) against three nominal velocities (1.5, 2.5 and 3 m s−1) and temperatures (5.5, 13.5 and 18.5°C), also including the changes between swimming modes (prolonged and sprint). Results showed that a nase of 20.8 cm mean fork length can develop a median swim speed that exceeds 20.7 BL s−1 (4.31 m s−1) during a median time of 3.4 s in sprint mode, or 12.2 BL s−1 (2.55 m s−1) for 23.7 s in prolonged mode under the warmest scenario. During prolonged swimming mode, fish were able to reach further distances in warmer water conditions for all situations, due to a greater swimming speed and FT, whereas during sprint mode, warmer conditions increased the swim speed maintaining the FT. In conclusion, the studied temperature range and flow velocity range influence fish swimming performance, endurance and distance travelled, although with some differences depending on the swimming mode. The provided information goes a step forward in the definition of real fish swimming capacities, and in turn, will contribute to establish clear passage criteria for thermo‐velocity barriers, allowing the calculation of the proportion of fish able to pass a barrier under different working scenarios, as well designing of the optimized solutions to improve the fish passage through river barriers.
Long‐term clinical outcomes of a fully covered self‐expandable metal stent for refractory pancreatic strictures in symptomatic chronic pancreatitis: An 11‐year follow‐up study
Authors: Ko Sung Woo , So Hoonsub , Oh Dongwook , Song Tae Jun , Park Do Hyun , Lee Sang Soo , Seo Dong‐Wan , Lee Sung Koo 
Published: January 2023

AbstractBackground and AimsA fully covered self‐expandable metal stent (FCSEMS) has recently been applied in the management of chronic pancreatitis patients with pancreatic strictures. However, related long‐term effects remain unclear. This study aimed to evaluate the long‐term outcomes of FCSEMS placement in chronic pancreatitis patients with refractory strictures.MethodWe retrospectively reviewed our database for patients undergoing FCSEMS placement for refractory pancreatic strictures between September 2008 and December 2010. The main outcomes were technical, radiological, and clinical success, as well as recurrence and adverse events.ResultsA total of 35 patients were included. Technical success was achieved in all patients. The median FCSEMS indwelling time was 3.2 months (interquartile range [IQR], 3.0–4.9 months). Radiological success was achieved in all patients (complete, n = 2; partial, n = 33). Clinical success was achieved in 29 patients (82.9%; complete analgesic cessation, n = 19; analgesic reduction >50%, n = 11). During the median follow‐up of 136 months, (IQR, 85.8–145.5 months), eight patients (22.9%) experienced recurrence. The median interval from stent removal to recurrence was 24.9 months (IQR, 11.3–30.3 months). Biliary obstruction, an early adverse event, occurred in two patients (5.7%); the late adverse event stent‐induced de novo stricture was observed in 17 patients (48.6%).ConclusionsOur findings suggest that an FCSEMS is effective for relieving refractory strictures in chronic pancreatitis. However, FCSEMSs were associated with stent‐induced de novo strictures in nearly half of the patients. Prospective studies are required to further evaluate the long‐term efficacy and safety of FCSEMSs in chronic pancreatitis.
Coming Apart While Scaling Up – Adoption of Logics and the Fragmentation of Organizational Identity in Science‐Based Ventures
Authors: Schou Peter Kalum 
Published: January 2023

AbstractWhen trying to commercialize, science‐based ventures often face contradicting institutional logics. While stakeholders appreciate scientific ability, they also increasingly demand concessions to a commercial logic focusing on efficiency and profit. To satisfy stakeholders, science‐based ventures must adapt their organizational identity to include the commercial logic. The study investigates this challenge, relying on a 24‐month in‐depth study of a venture in the photonics industry. Based on the findings, I developed a process model that outlines how the logics shift from compatibility to incompatibility during the adoption process, thereby causing the organizational identity to fragment. The paper contributes to research streams on organizational identity processes, dynamics of institutional logics in organizations, and scaling of science‐based ventures.
Palatability, glycemic, and insulinemic responses to various carbohydrate formulations: Alternatives for the diagnosis of insulin dysregulation in horses?
Authors: Warnken Tobias , Schaub Claudia , Delarocque Julien , Frers Florian , Feige Karsten , Sonntag Johanna , Reiche Dania Birte 
Published: January 2023

AbstractBackgroundOral glycemic challenge (GC) tests are recommended for diagnosis of insulin dysregulation (ID). Various protocols are used, but all have limitations in terms of palatability, ease of use, variable composition, geographic availability, or some combination of these.Hypothesis/ObjectiveTo evaluate newly developed formulations with defined carbohydrate composition for use as oral GCs.AnimalsThirty‐four horses and ponies in various metabolic states.MethodsOur objectives were carried out in 2 separate cross‐over experiments. First, the palatability and acceptance of various GCs (2 syrups, 1 granulate) offered for free intake were compared to glucose mixed in a chaff‐based diet. Subsequently, syrups were administered by syringe and compared to an oral glucose test using naso‐gastric tubing (tube OGT) to investigate the glycemic and insulinemic responses. Second, these variables were compared in the best performing GC‐formulations (granulate further optimized to pelleted formulation and 1 syrup) and a tube OGT. All GCs were administered with equivalent amounts of 0.5 g glycemic carbohydrates per kg body weight.ResultsOnly the GC pellets were consumed completely by all horses (consumption time 5 ± 2 min). When administered by syringe, the GC syrup also was well accepted. The insulin concentrations at 120 min correlated significantly between tube OGT and GC pellets (r = .717; P < .001) or GC syrup (r = .913; P < .001). The new GC syrup and GC pellets discriminate between healthy and ID horses.Conclusions and Clinical SignificanceThe GC pellets (DysChEq)™ and GC syrup can be used as palatable and well‐accepted oral GC tests for assessment of ID in horses.
Vector‐borne protozoan and bacterial pathogen occurrence and diversity in ectoparasites of the Egyptian Rousette bat
Authors: Szentiványi Tamara , Heintz Anne‐Caroline , Markotter Wanda , Wassef Jérôme , Christe Philippe , Glaizot Olivier 
Published: January 2023

AbstractBats are known reservoir hosts for a wide variety of parasites and pathogens, including bacteria and protozoans. Some of these pathogens are vector‐borne, and although their role is poorly studied, ectoparasites may contribute significantly to their transmission. The aim of this study was to molecularly detect the presence of vector‐borne microorganisms in bat‐associated ectoparasites to explore their diversity and distribution in these insects. We tested the presence of Bartonella spp., Polychromophilus spp., and Trypanosoma spp. in bat flies and bat fleas collected from 56 Egyptian Rousette bats (Rousettus aegyptiacus), using conventional PCR. We found a high prevalence of 43.9% (47/107) of Bartonella spp. in bat flies, but a low prevalence of 6.6% (4/61) in bat fleas. Polychromophilus and Trypanosoma DNA were absent in both bat flies and bat fleas. Furthermore, we found novel gltA Bartonella sequences, as well as genotypes that are highly similar to recently described and potentially zoonotic ones. Our results show high diversity of Bartonella in bat flies, however, their role in pathogen transmission is still unknown and should be further explored.
Knowledge and perceptions of nutrition assistance programmes among young adult students
Authors: Perry Michelle G. , Ashley Avery R. , Hood Lanae B. , Hagedorn‐Hatfield Rebecca L. 
Published: January 2023

AbstractThe purpose of this qualitative study was to investigate the perceptions of nutrition assistance programmes among young adult students in the United States, and to identify how the current social and political climate, including the COVID‐19 pandemic, has impacted these perceptions and the overall willingness of young adult students to participate in these programmes. Participants were recruited via email and social media to participate in 20‐min virtual, semi‐structured interviews. Twenty‐three participants, between the ages of 18 and 25 years from three states in the United States were interviewed. Ten participants reported having experienced food insecurity (FI) in their lifetime, with 21 participants currently having enough food to eat, while two sometimes did not currently have enough to eat. Seven participants had utilised nutrition programmes in their lifetime. Interviews were video and audio recorded, transcribed, and coded using a six‐step thematic analysis. Young adult students were largely unaware of nutrition assistance programmes and eligibility requirements but still perceived these programmes to be successful, with a higher proportion of the participants who had utilised a nutrition assistance programme in their lifetime expressing the view that they were generally successful compared to those who had never utilised one. Most were cognizant of the social stigma surrounding these programmes yet expressed a willingness to utilise them and reported an increased willingness to utilise nutrition assistance programmes as a result of the COVID‐19 pandemic. COVID‐19 made young adult students aware of FI and the important role nutrition assistance programmes play in our society. Young adult students expressed the belief that the Biden administration will have a positive impact on nutrition assistance programmes but had a general hesitation to discuss politics. The COVID‐19 pandemic has increased young adult students' willingness to utilise nutrition assistance programmes, although, access to these programmes remains low due to a lack of knowledge and general unawareness of programme availability and accessibility. Education is needed to improve overall knowledge of, and facilitate access to, nutrition assistance programmes while combating perceptions around stigma.
A protocol for exploring patients' and support peoples' experiences after prolonged critical illness
Authors: Best Amy , Harvey Clare , Minton Claire 
Published: January 2023

AbstractBackgroundImproved survival of critically ill people has increased the number of patients who experience an extended stay in intensive care units (ICU). Evidence suggests the complexities, vulnerabilities, and traumas created by critical illness are substantial for both patients and their support people with a number experiencing devastating impairments across multiple domains of health and function including physical, mental, cognitive, and social health. However, research on survivors predominantly focuses on those who have experienced a relatively short length of stay; only a limited number of studies seek to explore the experiences of survivors and their support people who have had a prolonged stay in intensive care.AimsTo describe the experiences of survivors of prolonged critical illness (invasively mechanically ventilated in ICU for ≥eight days) and their support people during the first 12 months following hospital discharge in New Zealand.Study designThis research will be a multi‐centre study recruiting from three intensive care units in New Zealand. A narrative inquiry methodology will be used to interview 6–8 former long stay patients and 6–8 support people of a former long stay patient. Each participant will be interviewed at 3‐, 6‐, 9‐, and 12‐months following hospital discharge. Data will be collected via narrative inquiry interviews. Data analysis will combine two theoretical frameworks: the Clandinin and Connelly narrative inquiry three‐dimensional space and the Fairclough situation, discourse and context framework.ResultsThe phenomenon of investigation will be experiences after prolonged critical illness explored longitudinally across the first‐year post‐hospital discharge.Relevance to clinical practiceThis protocol provides a methodological framework for exploring the lived experiences of survivors of prolonged critical illness and their support people. Data analysis will support understanding of the human journey of ICU survivorship and add to the body of knowledge on how to support post‐ICU recovery in this population. The barriers and enablers of survivorship at the micro, meso, and macro levels of the health service will also be illuminated.
Sex differences in neurodevelopmental trajectories in children with different levels of autistic traits
Authors: Nishimura Tomoko , Takahashi Nagahide , Okumura Akemi , Harada Taeko , Iwabuchi Toshiki , Nakayasu Chikako , Rahman Mohammad Shafiur , Uchiyama Satoshi , Wakuta Manabu , Nomura Yoko , Takei Nori , Senju Atsushi , Tsuchiya Kenji J. 
Published: January 2023

AimLittle is known about early manifestations of autism spectrum disorders (ASD) in females, including those who may be overlooked by the current diagnostic criteria. We longitudinally explored sex differences in the trajectories of cognitive and motor functions and adaptive behaviors in children with different levels of autistic traits.MethodsThe participants were 824 children from the Hamamatsu Birth Cohort for Mothers and Children (HBC Study), Japan, who were classified into three autistic trait groups—low, moderate, and high—based on the Social Responsiveness Scale–Second Edition. Cognitive and motor functions were measured at seven time‐points from 0.5 to 3.5 years of age using the Mullen Scales of Early Learning. Adaptive behaviors were measured at five time‐points from 2.7 to 9 years of age using the Vineland Adaptive Behavior Scales–Second Edition. Trajectories were depicted using latent growth curve modeling.ResultsSex‐specific trajectories were observed in the high‐autistic‐trait group, with only males showing a temporary decline in expressive language around the age of 2 years and a slight improvement thereafter. They also showed a slight improvement around 3 years in the adaptive behavior communication domain but a gradual downward trend later. Females in the high‐autistic‐trait group showed no distinct manifestation before the age of 3 years but showed a downward trend after 3.5 years in the adaptive behavior communication domain.ConclusionFemales and males with higher autistic traits than their same‐sex peers, independent of clinical diagnosis, may have different phenotypes in certain neurodevelopmental domains during infancy and early childhood.
Family policy, intrahousehold bargaining, and child health
Authors: Borga Liyousew Gebremedhin 
Published: January 2023

AbstractThis study examines the effects of an exogenous change in family policy in Ethiopia on women empowerment and the allocation of resources toward child health. Empowerment is formalized as an unobserved latent variable based on a large set of questions pertaining to women's autonomy and decision‐making power. Exploiting the time and regional variation in the implementation of the law, the study finds that early implementation of the reform increases women's access to information, literacy and education levels, and their assertiveness toward family planning and domestic violence. In addition, more decision power in the hands of women is found to have a positive impact on investments in the health and nutrition of children. The findings suggest that factors that do not enter the individual's preferences may affect outcomes for individuals and emphasize the role of intrahousehold heterogeneity. The results are robust to a battery of validity and specification checks.
The value of anti‐rods and rings antibodies in Chinese population of Dalian City: A retrospective study
Authors: Gu Yanan , Li Si , Wang Zhen , Yang Dong 
Published: January 2023

AbstractThe study aimed to investigate the clinical significance of anti‐rods and rings (anti‐RR) antibodies in antinuclear antibodies (ANAs) test samples retrospectively. The laboratory data and clinical details of patients with positive anti‐RR antibodies were collected and analysed between December 2017 and May 2022 in the First Affiliated Hospital of Dalian Medical University. A total of 72 665 patients were tested for ANAs. There were 45 632 patients discovered with positive ANAs (62.80%), only 131 patients presented with anti‐RR antibodies (0.18%), among which only 68 patients were hospitalized patients with a definitive diagnosis. Among the 68 patients with a definitive diagnosis, 8 of 68 (11.8%) had autoimmune diseases, and 19 of 68 (27.9%) had renal diseases. Other diseases included liver disease, pulmonary disease, cerebral ischemia, cerebral infarction, chronic cardiac failure and venous thromboembolism. The detection rate of high titre(≥1:1000) anti‐RR antibodies is significantly higher in autoimmune diseases.
Methodological rigor and reporting quality of clinical practice guidelines for adults hospitalized with bacterial pneumonia: a scoping review protocol
Authors: Hagedorn Wonder Amy , Nick Jan M. , Adeoye Olayemi O. , Sehgal Gurmeet 
Published: January 2023

Objective:
This scoping review presents a profile of methodological rigor and reporting quality of clinical practice guidelines for adults hospitalized with bacterial pneumonia.

Introduction:
An ideal clinical practice guideline is evidence-based and the product of a rigorous and robust literature-vetted process, yet reports show that rigor is not being achieved. Moreover, a new vulnerable population has been identified due to COVID-19. Preliminary searches yielded no scoping or systematic reviews on methodological rigor and reporting quality of clinical practice guidelines used for managing bacterial pneumonia in hospitalized adults.

Inclusion criteria:
This review will consider current national and international clinical practice guidelines for management of hospitalized adult patients with either suspected or confirmed primary bacterial pneumonia. The review will include adult patients with multiple diagnoses if there is a clearly delineated clinical practice guideline for pneumonia.

Methods:
A 3-step search strategy will be conducted using JBI methodology for scoping reviews. After an initial MEDLINE search for keywords, a broad search of 7 databases, 1 simultaneous platform, gray literature, specialty organizations, and international guideline groups will be conducted from 2017 to present, in any language. Reference lists will be screened for additional sources. A 2-step screening process will be used to identify eligible clinical practice guidelines. Three reviewers will independently extract data, using a standardized form. Domain scores will be analyzed and presented as percentages, and the results will be interpreted as map trends.

Scoping review key details available in Open Science Framework:

https://osf.io/h896x
Impaired dendritic spike generation in the Fragile X prefrontal cortex is due to loss of dendritic sodium channels
Authors: Brandalise Federico , Kalmbach Brian E. , Cook Erik P. , Brager Darrin H. 
Published: January 2023

AbstractPatients with Fragile X syndrome, the leading monogenetic cause of autism, suffer from impairments related to the prefrontal cortex, including working memory and attention. Synaptic inputs to the distal dendrites of layer 5 pyramidal neurons in the prefrontal cortex have a weak influence on the somatic membrane potential. To overcome this filtering, distal inputs are transformed into local dendritic Na+ spikes, which propagate to the soma and trigger action potential output. Layer 5 extratelencephalic (ET) prefrontal cortex (PFC) neurons project to the brainstem and various thalamic nuclei and are therefore well positioned to integrate task‐relevant sensory signals and guide motor actions. We used current clamp and outside‐out patch clamp recording to investigate dendritic spike generation in ET neurons from male wild‐type and Fmr1 knockout (FX) mice. The threshold for dendritic spikes was more depolarized in FX neurons compared to wild‐type. Analysis of voltage responses to simulated in vivo ‘noisy’ current injections showed that a larger dendritic input stimulus was required to elicit dendritic spikes in FX ET dendrites compared to wild‐type. Patch clamp recordings revealed that the dendritic Na+ conductance was significantly smaller in FX ET dendrites. Taken together, our results suggest that the generation of Na+‐dependent dendritic spikes is impaired in ET neurons of the PFC in FX mice. Considering our prior findings that somatic D‐type K+ and dendritic hyperpolarization‐activated cyclic nucleotide‐gated‐channel function is reduced in ET neurons, we suggest that dendritic integration by PFC circuits is fundamentally altered in Fragile X syndrome.
imageKey points
Dendritic spike threshold is depolarized in layer 5 prefrontal cortex neurons in Fmr1 knockout (FX) mice.
Simultaneous somatic and dendritic recording with white noise current injections revealed that larger dendritic stimuli were required to elicit dendritic spikes in FX extratelencephalic (ET) neurons.
Outside‐out patch clamp recording revealed that dendritic sodium conductance density was lower in FX ET neurons.
In Situ Generated Dispersed Catalysts Based on Molybdenum and Tungsten Phosphides in Hydroprocessing of Guaiacol
Authors: Golubeva M. A. , Mukhtarova M. , Bugaev A. L. , Naranov E. R. 
Published: January 2023

Abstract
Amorphous catalysts based on molybdenum and tungsten phosphides were prepared in situ from oil-soluble precursors such as triphenylphosphine and carbonyls of the corresponding metals during hydrodeoxygenation of guaiacol. These catalysts were characterized by powder X-ray diffraction, X-ray photoelectron spectroscopy, extended X-ray absorption fine structure spectroscopy, and transmission electron microscopy. After 6 h of reaction at 320–380°C and an initial hydrogen pressure of 5 MPa, the guaiacol conversion amounted to 89–91% in the presence of the molybdenum phosphide catalyst and 80–86% with tungsten phosphide. The selectivity towards phenol as the main reaction product reached as high as 80% in the presence of molybdenum phosphide (360°C, 6 h) and 78% in the tungsten phosphide case (340°C, 1 h). In the presence of both catalytic systems, the reaction products also contained anisole, cresols, and toluene.