bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential effect of pre-treatments on antinutritional and mineral composition of garden cress seed (Lepidium sativum)
Authors: Malhotra Umang , Sontakke Manmath 
Published: March 2023

Abstract
This study aimed to screen an effective combination of treatment times for the processing of garden cress seeds (GCS) to enhance nutritional value. GCS was subjected to different combinations of pre-treatments, namely boiling (10 min), blanching (3 min), and soaking (12 hr) followed by roasting (2.5, 5 and 7.5 min), respectively which were compared with control sample for maximum mineral retention, especially calcium. It was found that treatment with SR 2.5 increased total protein and ash to 22.90% and 5.24%, respectively. BoR 7.5 treatment increased the fat content to 23.86%. The greatest calcium retention (378 mg/100 g) was observed when treating SR 7.5, as the ANF decreased from 458.3 to 414.5 mg/100 g for phytate and from 152.11 to 93.93 mg for oxalate /100 g. Therefore, treatment with SR 7.5 can be considered as the best pre-treatment to improve the nutritional value of GCS and reduce the anti-nutritional components.
Swarm Intelligence techniques for optimization of Microgrid with Renewable Energy System
Authors: Vaish Jayati , Tiwari Anil Kumar , Seethalekshmi K. 
Published: March 2023

Abstract
Recently, clean power generation has received a lot of attention in modern power systems as a means to provide sustainability and high flexibility in the power industry. Due to this, modern energy systems are now reliant on Microgrids (MGs), which can easily access and operate Renewable Energy Systems (RES) and other Distributed Generations. The use of Microgrids plays a vital role in implementing clean and renewable energy. This will enhance energy security, making considerable financial savings, and lowering greenhouse gas emissions. In this paper, a grid-connected Microgrid system is considered as test model that includes solar photovoltaic (PV), wind turbine (WT), micro gas turbine (MT), fuel cell (FC), and battery energy storage system (BESS). The developed system is presented as a multi-objective function with constraints that can be resolved by a significant optimization method. Various commonly used Swarm Intelligence (SI) based meta-heuristic optimization techniques such as Ant Colony Optimization (ACO), Particle Swarm Optimization (PSO), Artificial Immune System (AIS), Bacteria Forging Optimization (BFO), Shuffled Frog Leaping Algorithm (SFLA), Artificial Bee Colony (ABC), Cuckoo Search (CS), Bat Algorithm (BA), Firefly Algorithm (FFA), Krill Herd (KH), Grey Wolf Optimization (GWO), Whale Optimization Algorithm (WOA) can be used to optimize above stochastic multi-objective problem of Microgrid. To assist researchers in selecting the best optimization approaches for their study, a comparison of above-mentioned SI based optimization techniques is provided in this paper. The discussion also includes upcoming research issues for Microgrid operation optimization.
Management of ureteric stones in children: a comparison between pneumatic lithotripsy with Ho: YAG laser lithotripsy .Which is better
Authors: Mohemmed Maged Asgher , Attar Firas Shakir , Abdullah Abdullah Yousif 
Published: March 2023

Abstract
Background
When coming to discuss urinary stone disease in children, it seems that there are so many differences regarding etiology, incidence and the course of the disease as compared to adults. The introduction of semi rigid small caliber ureteroscopes and lithotripsy modalities using pneumatic and lithotripsy holmium: yttrium aluminum- garnet ( Ho: YAG ) laser lithotripsy has improved the success rate and decreased the incidence of complications of treatment of ureteric calculi. The aim of this study is to compare the use of Ho: YAG and pneumatic lithotripsy in the treatment of ureteric stones in children in our center.
Materials and methods
This is a prospective study that included 100 patients presenting with ureteric stones for the period from March 2020 to April 2022. The patients were randomized into two groups; group I included 49 patients with ureteric stones who were treated with means of Ho: YAG laser lithotripsy and group II included 51 patients with ureteric stones who were treated with of pneumatic lithotripsy. The outcome of the study was to evaluate the success of fragmentation and development of complications. Statistical analysis was achieved by chi square test and t test was used with a p value of less than 0.05 was considered as significant.
Results
Fifty seven stones were treated by laser while 50 stones treated by pneumatic lithotripsy. The success rate of fragmentation was higher in the laser group with a significant difference (P value 0.032).The study showed a lower rate of complications among the patients treated with laser lithotripter.
Conclusion
Laser lithotripsy is an effective and safe method for treating ureteric stones in children. It looks that it is more effective in stone fragmentation and having less complication rate than pneumatic lithotripsy.
Expression of Trx-1, HIF-1α and their associations with clinicopathological parameters in gastric cancer
Authors: Niu Guangcai , Ma Xiangdong 
Published: March 2023

AbstractBackground Although it is only a small redox protein, Thioredoxin-1 (Trx-1) can have a significant impact in many biological processes. In recent years, studies on the increased Trx-1 expression in different solid tumors have gradually increased, but its clinical and diagnostic significance in gastric cancer (GC) have not been confirmed. HIF-1α (Hypoxia-inducible factor-1α) plays an active role in many tumors’ metabolism, while the relevance between its expression levels and clinical value in GC remains to be investigated. Methods: Western blot (WB) and quantitative PCR (qPCR) were used to detect HIF-1α and Trx-1 mRNA and protein level in 20 freshly frozen GC and corresponding normal-tissues. In addition, the protein level of Trx-1 and HIF-1α in 162 GC were determined by immunohistochemistry (IHC) test. The relevance between HIF-1α and Trx-1 expression and the clinicopathological characteristics in GC was assessed as well. And Cox proportional risk model was applied to determine independent prognostic indicators. Results: When HIF-1α level increased, the Trx-1 mRNA and protein levels increased obviously in GC tissues, and they both were related to a bad prognosis (P < 0.001). There was an obvious positive relevance (r = 0.578, P = 0.000) between Trx-1 and HIF-1α expressions. Through multivariate analysis, for GC prognosis, Borrmann type, Trx-1 and HIF-1α were independent predictors (P < 0.001). Conclusion For GC patients, both Trx-1 and HIF-1α may be prospective prognostic indicators and therapeutic target.
Willingness to Pay for Forest Conservation: An Empirical Investigation in Simlipal Forest
Authors: Saha Debolina , Agarwalla Shradha 
Published: March 2023

Abstract
The use and non-use values of environmental goods and services are often discussed in literature. This study shows suitability of using contingent valuation method (CVM) in forestry analysis, and applies both closed-ended and open-ended bidding formats to determine the willingness to pay of forest conservation cum non-use value of Simlipal forest in India, from the perspective of forest dwellers. Since the use value is market determined and non-use values go beyond market mechanism, this type of valuation exercise keeps relevance in natural resource conservation and management. Findings of the study clearly highlight eagerness of forest dwellers in natural resource preservation so as to enjoy its benefits in a sustainable manner. Analysis of the key factors affecting the valuation result recommends that development planning should be oriented towards reducing vulnerability of forest dwellers’ life which arises mainly due to miserable economic conditions in the absence of proper livelihoods. Though the forest dwellers get provisioning services from forests, they are also aware of the role of forest in supporting and regulating environmental balance. Hence the study is suggestive of the fact that government’s incentive-sharing mechanism within the ambit of existing participatory forest management system should need corrective measures so that the local communities can derive adequate economic benefits from it for their sustenance, which eventually would reduce forest dependence and ensure ecological integrity.
JEL Classification: A14, C50, C81, I3, Q2, Q51
Influence of electric field on IgG positioning and its immobilization for solid immunosensing substrates
Authors: Diyya Srujana 
Published: March 2023

Abstract
Most of the proteins are polar by their structural configuration, their stereochemistry entails overall charge of the molecule. In this study, Immunoglobulin G (IgG) is evaluated for its dipolar nature. An exclusive immunoassay pattern is designed to validate the idea by controlling the IgG orientation with external application of the electric field (EF). It includes mathematical estimations of the torque produced and the EF strength required to orient a single IgG molecule in normal room temperatures.In current pandemic scenario, the necessity of tests that provide clinical analysis of an individual is inevitable; thereby the use of immunoassay based rapid invitro diagnostic (IVD) test devices have become the most sort after point of care devices. The device configured in this study also explains the IgG orientation and immobilization post influence of EF in two dimensional geometry of flowchannel; and how it provides a platform for detection of the analytes with higher sensitivity. Therefore, this is also an attempt towards miniaturization of biosensor and to improve the signal intensity while optimizing the signal to noise ratio (SNR). Imparting qualities that suffice a stable, robust, portable sensing platform for a biosensor remains an added objective of this research.
Effect of papillary muscle and trabeculae on left ventricular function analysis via computed tomography
Authors: Kim Minji , Ha Taeyang , You Seulgi , Kim Tae Hee , Kang Doo Kyoung 
Published: March 2023

Abstract
Deciding whether to include or exclude the papillary muscles and trabeculae to blood pool is essential, because quantifications of left ventricular (LV) functional parameters and myocardial mass are significantly affected. As a result, such inclusion or exclusion might produce different indices for diagnosis and therapy. Using cardiac CT, we obtained standard values of the portion of papillary muscle and trabeculae in normal adults, and to find out how the inclusion or exclusion of papillary muscle and trabeculae affect LV functional parameters depending on the patient group. Excluding the papillary muscles from the LV mass results in easier automated contour detection using CT. The percentage portions of papillary muscle and trabeculae to LV end-diastolic volume (EDV) and LV mass (LVM) were 11.9 ± 5.6% and 20.2 ± 4.3%, respectively, significantly affecting disease diagnosis. Therefore, imaging should be consistent at follow-up and include or exclude the papillary muscles and trabeculae to avoid introducing significant differences between measurements.
Magnetic and Quantum Flux Fields with Potential in a Cosmic Dislocation and Thermo-Magnetic Properties
Authors: Ahmed Faizuddin 
Published: March 2023

Abstract
In this work, the quantum dynamics of charge particles interacting with anharmonic oscillator potential in the presence of magnetic and quantum flux fields in a cosmic dislocation are investigated. In fact, it is shown that the energy levels and wave function are influenced by a cosmic dislocation and gets modified. In addition, the eigenvalue solution are modified by the magnetic and quantum flux fields compared to the flat space result with this potential. Afterwards, we utilize this eigenvalue solution to molecular potential models (harmonic oscillator, pseudoharmonic, Coulomb potentials) and presented the eigenvalue solutions. Finally, we study the thermodynamic properties and magnetic properties of the quantum system at finite temperature T ≠ 0 and calculate the partition function and other functions, such as Helmholtz free energy, mean energy, specific heat capacity, entropy, and the persistent currents and analyze the effect of cosmic dislocation and external fields with this potential.
PACS 03.65.Pm · 03.65.Ge · 98.80.Cq · 02.30.Gp · 05.70.C
Forensic DNA Phenotyping: a review on SNP panels, genotyping techniques, and prediction models
Authors: Ortuño Nuria Terrado , May Patrick 
Published: March 2023

Abstract
In the past few years, forensic DNA phenotyping (FDP) has attracted a strong interest in the forensic research. Among the increasing publications, many have focused on testing the available panels to infer biogeographical ancestry (BGA) on less represented populations and understanding the genetic mechanisms underlying externally visible characteristics (EVC). However, there are currently no publications that gather all the existing panels limited to FDP and discuss the main technical limitations of the technique. In this review, we performed a bibliographic search in Scopus database of FDP-related literature, which resulted in a total of 48, 43 and 15 panels for BGA, EVC and both BGA and EVC inference, respectively. Here we provide a list of commercial and non-commercial FDP panels and the FDP limitations regarding the lack of harmonization in terms of terminology (i.e., categorization and measurement of traits) and reporting, the lack of genetic knowledge and environment influence to select markers and develop panels, and the debate surrounding the selection of genotyping technologies and prediction models and algorithms. In conclusion, this review aims to be an updated guide and to present an overview of the current FDP-related literature.
Construction and empirical research of the evaluation index system of environmental protection enterprises’ competitiveness based on the Delphi and AHP methods
Authors: Wu Huichao , Li Chenguang , Liu Zhen , Guo Yingzi , Li Yong , Hou Xiaodong , Li Yuanyuan , Zhao Shasha , Li Fengmin 
Published: March 2023

Abstract

The environmental protection industry has become an important support entity for the construction of ecological civilization and economic growth in China. However, there is little research on the competitiveness of environmental protection enterprises (EPEs). The construction of a set of scientific, comprehensive, practical, qualitative, and quantitative evaluation index systems is an important prerequisite for the sustainable and healthy development of the industry. Based on the literature analysis, semi-structured interviews with experts, and the Delphi method, the evaluation indicators for the competitiveness of EPEs were determined. Qualitatively, the evaluation index system of the competitiveness of EPEs contained 5 primary indicators, 12 secondary indicators, and 39 tertiary indicators. The analytic hierarchy process was used to determine the weights of indicators at each level. The primary indicators in order of weighting were organizational management capability, business environment, financial capability, innovation capability, and social responsibility, with corresponding weights of 26.13, 24.82, 21.76, 19.60, and 7.68%, respectively. Eight A-share listed EPEs in the water sector were selected for competitive evaluation. The evaluation index system of EPEs' competitiveness, being scientific-practical, combined, and quantitative, was constructed to provide a reference for the comprehensive evaluation of enterprises and the sustainable and healthy development of the industry.
Computational Analysis to Predict Drug Targets for the Therapeutic
Management of Mycobacterium avium sub. Paratuberculosis
Authors: Mohinani Taruna , Saxena Aditya , Singh Shoor Vir 
Published: March 2023

Background:
Mycobacterium avium sp. paratuberculosis (MAP) is a pathogen, which
causes paratuberculosis in animals; it has also been found to be associated with a number of autoimmune
disorders in humans. The emergence of drug resistance has also been found in this bacillus
during disease management.

Objective:
The present study’s focus was to identify potential therapeutic targets for the therapeutic
management of Mycobacterium avium sp. paratuberculosis infection by in silico analysis.

Methods:
Differentially-expressed genes (DEGs) can be good drug targets, which can be identified
from microarray studies. We used gene expression profile GSE43645 to identify differentiallyexpressed
genes. An integrated network of upregulated DEGs was constructed with the STRING database
and the constructed network was analyzed and visualized by Cytoscape. Clusters in the proteinprotein
interaction (PPI) network were identified by the Cytoscape app ClusterViz. MAP proteins predicted
in clusters were analyzed for their non-homology with the human proteins, and homologous
proteins were excluded. Essential proteins and cellular localization analysis and the physicochemical
characteristics prediction were also done. Finally, the druggability of the target proteins and drugs that
can block the targets was predicted using the DrugBank database and confirmed by molecular docking.
Structural prediction and verification of drug target proteins were also carried out.

Results:
Two drug targets, MAP_1210 (inhA) and MAP_3961 (aceA), encoding enoyl acyl carrier
protein reductase and isocitrate lyase enzymes, respectively, were finally predicted as potential drug
targets.

Conclusion:
Both of these proteins have been predicted as drug targets in other mycobacterial species
also, supporting our results. However, further experiments are required to confirm these results.
"¿Prestanombres o político por derecho propio?". El gobierno de Manuel González: relecturas desde la prensa (1880-1884)
Authors: Covarrubias José Enrique 
Published: March 2023

Reseña de:El gobierno de Manuel González: relecturas desde la prensa (1880-1884). Edición de Lilia Vieyra Sánchez y Edwin Alcántara Machuca. México: Universidad Nacional Autónoma de México, Instituto de Investigaciones Bibliográficas, 2021, 687 pp., il. ISBN: 978-607-30-5059-3.
Cooperación para el desarrollo, relaciones internacionales y políticas públicas. Teorías y prácticas del diálogo Euro-latinoamericano.
Authors: Ciurlo Alessandra 
Published: March 2023

Carlo Tassara, con una larga trayectoria en el ámbito de las relaciones internacionales y la cooperación entre Europa y América Latina, en este libro afronta el tema de la cooperación euro-latinoamericana para el desarrollo creando un círculo virtuoso entre el análisis teórico y la práctica concreta, una visión realista que potencia el impacto positivo y los alcances reales de los programas y proyectos realizados y por realizar.
Al partir de una reseña de las diversas perspectivas y marcos conceptuales que han imperado desde el Segundo Posguerra, el autor señala su evolución y contradicciones y, sobre todo, evidencia cuáles son los retos que se perfilan en el campo de la cooperación y de las relaciones internacionales hacia el futuro de un mundo cada vez más complejo e interconectado. Este libro constata, además, la importancia que estas materias sean consideradas desde una perspectiva interdisciplinaria, teniendo en cuenta la diversidad de actores y disciplinas involucradas. Es por esto que el autor enfatiza la interconexión entre la cooperación para el desarrollo, las relaciones internacionales y las políticas públicas que se ponen en marcha a partir ello.
Realizado
Por Alessandra Ciurlo
Socióloga colombiana residente en Italia, PhD en Ciencias sociales y Docente de Investigación Social en la Pontificia Universidad Gregoriana de Roma. Ha trabajado principalmente en temas de migración latinoamericana hacia Europa y en particular hacia Italia, familias en contexto migratorio y segundas generaciones, con especial atención a sus implicaciones internacionales y a la cuestión de género. Asesora también a varias asociaciones de migrantes
Caracterización de unidades productoras de arepas ocañeras en la ciudad de Ocaña
Authors: D´vera Pérez Carlo Fernando 
Published: March 2023

El Área de Desarrollo con apoyo del Área de Fomento Empresarial y el Centro de Estudios e Investigación del Sector Solidarios, realizó el Censo Sectorial con el objeto de identificar, cuantificar y determinar las características propias de las unidades productoras de arepas ocañeras en la ciudad de Ocaña, en cuanto a tamaño, infraestructura, tecnificación, ubicación geográfica, organización jurídica, nivel de informalidad en el sector, nivel de escolaridad y necesidades de capacitación, además de realizar un diagnóstico para la conformación de una empresa bajo modelos de asociatividad dedicada a aprovisionamiento y comercialización. Esto con el fin de obtener elementos de juicio suficientes que permitan brindar herramientas y proyectos que contrarresten la falta de desarrollo el sector, para el planteamiento de estrategias de mejoramiento de los niveles de productividad y desarrollo empresarial local y regional.
Para lograr el cumplimiento de los objetivos planteados, se plantea una investigación cuantitativa de tipo descriptiva que busca especificar las propiedades y características del sector, así como también el perfiles de las unidades productivas. Por otra parte, para la recolección de la información se planteó utilizar como instrumento la encuesta que permitirá la recolección de la información.
La identificación de la población, se realizó haciendo un barrido de Ocaña comuna por comuna y barrio por barrio comenzando por el norte y terminando en sur, al mismo tiempo que se utilizó el método de muestro por bola de nieve para poder garantizar la identificación del 100% de las unidades productivas.
En cuanto a los resultados de la investigación, se detecta que el 92,6% de la población inmersa en el proceso de producción son mujeres, y que existen un bajo nivele de educación y escolaridad. Por otra parte, se detectó también que los estratos socio económicos en el sector, la mayor participación corresponde a estratos 1 y 2, donde la producción de arepas se hace en casas de familia, lo que evidencia que dicha actividad se considera de supervivencia y no es vista como una oportunidad de desarrollo para la creación e impulso de industria y marcas consolidadas.
Beneficios de programación ganada aplicada a proyectos en Colombia
Authors: Armando Sánchez Nelson , Bernal Villanueva Jairo Abraham , Bernal López Cesar Daniel Andres 
Published: March 2023

El método de valor ganado (EVM) es un excelente método de seguimiento y control de costos, pero se cuestiona su validez en la gestión de cronogramas sobre todo cuando los proyectos se retrasan más allás del cronograma aprobado. El método de programación ganada (ESM) presenta un modelo para solucionar las carencia de indicadores objetivos y oportunos, para la toma de decisiones.
Este informe de estudio comparativo, presenta conclusiones respecto a los beneficios y limitantes en términos de gestión de cronogramas, analizando información histórica de gestión de cronogramas de proyectos del sector real colombiano elegidos de manera aleatoria, usando los métodos de (a) valor ganado (EVM) y (b) programación ganada (ESM); se enfatizó en el impacto de utilizar los métodos, al inicio y final del cronograma, asimismo en la entrega de información oportuna para toma de decisiones. Las conclusiones brindan argumentos a los gerentes de proyectos y Oficinas de proyectos PMO a la hora de seleccionar el método de seguimiento y control, más apropiado para su metodología de gestión de proyectos.