bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of SARS COV-2 IgG Anti-N as an Independent Marker of Exposure to SARS COV-2 in an Unvaccinated West African Population
Authors: Abdullahi Adam , Frimpong James , Cheng Mark T. K. , Aliyu Sani H. , Smith Colette , Abimiku Alash’le , Phillips Richard Odame , Owusu Michael , Gupta Ravindra K. 
Published: August 2023

ABSTRACT.
Determination of previous SARS-COV-2 infection is hampered by the absence of a standardized test. The marker used to assess previous exposure is IgG antibody to the nucleocapsid (IgG anti-N), although it is known to wane quickly from peripheral blood. The accuracies of seven antibody tests (virus neutralization test, IgG anti-N, IgG anti-spike [anti-S], IgG anti–receptor binding domain [anti-RBD], IgG anti-N + anti-RBD, IgG anti-N + anti-S, and IgG anti-S + anti-RBD), either singly or in combination, were evaluated on 502 cryopreserved serum samples collected before the COVID-19 vaccination rollout in Kumasi, Ghana. The accuracy of each index test was measured using a composite reference standard based on a combination of neutralization test and IgG anti-N antibody tests. According to the composite reference, 262 participants were previously exposed; the most sensitive test was the virus neutralization test, with 95.4% sensitivity (95% CI: 93.6–97.3), followed by 79.0% for IgG anti-N + anti-S (95% CI: 76.3–83.3). The most specific tests were virus neutralization and IgG anti-N, both with 100% specificity. Viral neutralization and IgG anti-N + anti-S were the overall most accurate tests, with specificity/sensitivity of 100/95.2% and 79.0/92.1%, respectively. Our findings indicate that IgG anti-N alone is an inadequate marker of prior exposure to SARS COV-2 in this population. Virus neutralization assay appears to be the most accurate assay in discerning prior infection. A combination of IgG anti-N and IgG anti-S is also accurate and suited for assessment of SARS COV-2 exposure in low-resource settings.
Update on the Geographic Distribution of the Intermediate Host Snails of Schistosoma mansoni on St. Lucia: A Step Toward Confirming the Interruption of Transmission of Human Schistosomiasis
Authors: Mukaratirwa Samson , Laidemitt Martina R. , Hewitt Reynold , Sengupta Mita E. , Marchi Silvia , Polius Consortia , Belmar Sharon , Scholte Ronaldo G. C. , Perez Freddy , Stensgaard Anna-Sofie , Vennervald Birgitte J. , Willingham Arve L. , Loker Eric S. 
Published: August 2023

ABSTRACT.
To provide information to guide considerations of declaring interruption of transmission of human schistosomiasis due to Schistosoma mansoni on St. Lucia, we undertook an island-wide survey in June–July 2022 to determine the presence of Biomphalaria snails, the intermediate hosts of S. mansoni, and their infection status. Snail surveys were carried out at 58 habitats to determine presence of Biomphalaria snails followed by examination of the collected snails for evidence of infection with S. mansoni. Furthermore, water samples were collected at the snail habitats and screened for presence of S. mansoni DNA using an eDNA approach. We found B. glabrata present in one habitat (Cul de Sac) where it was abundant. Specimens provisionally identified as Biomphalaria kuhniana were recovered from 10 habitats. None of the Biomphalaria specimens recovered were positive for S. mansoni. None of the eDNA water samples screened were positive for S. mansoni. Experimental exposures of both field-derived and laboratory-reared St. Lucian B. glabrata and B. kuhniana to Puerto Rican and Kenyan-derived S. mansoni strains revealed B. glabrata to be susceptible to both and B. kuhniana proved refractory from histological and snail shedding results. We conclude, given the current rarity of B. glabrata on the island and lack of evidence for the presence of S. mansoni, that transmission is unlikely to be ongoing. Coupled with negative results from recent human serological surveys, and implementation of improved sanitation and provision of safe water supplies, St. Lucia should be considered a candidate for declaration of interruption of human schistosomiasis transmission.
HASIL KARYA CIPTA LAGU ANAK-ANAK
Authors: Samsuri Samsuri , Astuti Yuli 
Published: August 2023

The research entitled “The Creative work of Children’s Songs”. Raising the problem in this research is how to create children’s songs for elementary school level? This study aims to describe the process of creating songs for children at the elementary school level. The approach used in this research is a qualitative approach with a descriptive type of research. The subjects in this study were elementary school children at the high level, namely grades are IV-VI. While the object to be studied was a song entitled Ayah Bunda which was created by the researcher. The data in this studi were collected using literature study, observation, and documentary. From the results of the study, it showed that elementary school children in high grade were able to sing a song created by researcher entitled Ayah Bunda with a range of tones that were appropriate for their age. The lyris of the song were created according to the age of the children, which is about the happiness of children when they are loved and pampered by their parents. As a feeling of gratitude and gratitude, children should always pray for their parents so that they live long and always be healthy.
Abstrak
Penelitian yang berjudul “Hasil Karya Cipta Lagu Anak-Anak”. Mengangkat masalah dalam penelitian ini adalah bagaimana hasil karya cipta lagu anak-anak untuk tingkat sekolah dasar?. Penelitian ini bertujuan untuk mendeskripsikan proses penciptaan lagu untuk usia anak-anak pada tingkat sekolah dasar. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Subjek dalam penelitian ini yaitu anak-anak sekolah dasar pada tingkat kelas tinggi yaitu kelas IV-VI), sedangkan Objek yang akan diteliti yaitu lagu yang berjudul Ayah Bunda hasil ciptaan peneliti. Data pada penelitian ini dikumpulkan dengan teknik studi pustaka, observasi dan dokumentasi. Dari hasil penelitian menunjukkan bahwasanya, anak-anak sekolah dasar kelas tinggi mampu menyanyikan lagu hasil ciptaan peneliti yang berjudul Ayah Bunda dengan jangkauan nada yang sesuai dengan usia mereka. Lirik lagu yang diciptakan sesuai dengan usia anak-anak yaitu berisi tentang kebahagian anak-anak saat disayang dan dimanjakan oleh kedua orang tuanya. Sebagai rasa bersyukur dan terimakasih, anak-anak sudah sepatutnya selalu mendoakan ayah bundanya agar panjang umur dan sehat selalu.
PENGARUH PENERAPAN MODEL PJBL (PROJECT-BASED LEARNING) TERHADAP KETERAMPILAN ABAD 21
Authors: Undari Mayrisa , Darmansyah  , Desyandri  
Published: August 2023

Abstrak
Penelitian ini bertujuan membahas bagaimana pengaruh penerapan model PjBL (Project-Based Learning) terhadap keterampilan abad 21 yang mencakup Critical Thinking, Communication, Creative Thinking, dan Collaboration yang sering disebut keterampilan 4C. Jenis penelitian ini kualitatif deskriptif dengan metode systematic literature review yang terdiri dari beberapa taha. Pertama planning, dimana kita menentukan topik yang akan dibahas, penetapan kriteria artikel yang akan digunakan. Kedua Conducting, proses mencari, memilih artikel dan sintesis data. Ketiga reporting, penulisan hasil systematic literature review. Berdasarkan kajian 17 artikel nasional, penerapan model PjBL merupakan upaya yang banyak dilakukan untuk meningkatkan keterampilan abad 21. Hasil penelitian yang dilakukan dapat diketahui bahwa penggunaan model PjBL dapat meningkatkan keterampilan abad 21 yang mencakup kemampuan berfikir kritis, komunikasi, kreatifitas dan kolaborasi.
Abstract
This study aims to discuss how the influence of the application of the PjBL (Project-Based Learning) model has on 21st century skills which include Critical Thinking, Communication, Creative Thinking, and Collaboration which are often called 4C skills. Type study this qualitative descriptive with method a systematic literature review consisting of from a number of haha . First planning , where our determine topic to be discussed , determined criteria article to be used . Second Conducting, process of searching , choosing article and data synthesis . Third reporting , writing results systematic literature review . Based on review of 17 articles national level , implementation of the PjBL model is lot of effort conducted for increase Skills 21st century . Results research conducted _ could is known that use of the PjBL model could increase Skills 21st century that includes ability think critical , communication , creativity and collaboration .
PENGEMBANGAN LKPD MEMBACA PERMULAAN BERBASIS PERMAINAN KATA DENGAN MENGGUNAKAN METODE SAS PADA KELAS I SEKOLAH DASAR
Authors: Karima Melda , Murniviyanti Liza , Prasrihamni Mega 
Published: August 2023

This study aims to produce a product in the form of Student Worksheets based on word games using the Structural Analytical Synthetic method. This Research and Development uses the Analysis, Design, Development, Implementation, Evaluation (ADDIE) model. The trial was conducted at SD Negeri 20 Banyuasin I with data collection techniques in the form of interviews, questionnaires (questionnaires) and documentation. The results of the research and development that have been carried out show that: the validation assessment by material experts, linguists and media experts gets a score of 84.74 with a very valid category; the assessment of the teacher and student questionnaires got a score of 84.34 with a very practical category; the pretest and posttest assessments of students obtained 0.74 from the results of the n-gain calculation with a high category which means it is very effective. It was concluded that the Student Worksheet reading the beginning based on word games using the SAS method in grade I Elementary School was very valid, practical and effective and feasible to use.
Abstrak
Penelitian ini bertujuan untuk menghasilkan produk berupa Lembar Kerja Peserta Didik membaca permulaan berbasis permainan kata dengan menggunakan metode Struktural Analitik Sintetik. Penelitian dan Pengembangan (Research and Development) ini menggunakan model Analisis, Desain, Pengembangan, Penerapan, Evaluasi (ADDIE). Uji coba dilakukan di SD Negeri 20 Banyuasin I dengan teknik pengumpulan data berupa wawancara, angket (kuesioner) dan dokumentasi. Hasil dari penelitian dan pengembangan yang telah dilaksanakan menunjukkan bahwa: penilaian validasi oleh ahli materi, ahli bahasa dan media mendapatkan skor 84,74 dengan kategori sangat valid; penilaian angket guru dan peserta didik mendapatkan skor 84,34 dengan kategori sangat praktis; penilaian pretest dan posttest peserta didik diperoleh 0,74 dari hasil perhitungan n-gain dengan kategori tinggi yang berarti sangat efektif. Disimpulkan bahwa Lembar Kerja Peserta Didik membaca permulaan berbasis permainan kata dengan menggunakan metode SAS pada kelas I Sekolah Dasar ini sangat valid, praktis dan efektif serta layak untuk digunakan.
Long-term outcomes of isolated limb perfusion with hyperthermia in patients with soft tissue sarcomas
Authors: Kharatishvili T. K. , Petrochenko N. S. , Gribkova E. I. , Buidenok Yu.  V. , Kaspshik S. M. , Aliyev M. D. 
Published: August 2023

In case of locally advanced soft tissue sarcomas of the extremities (STS), the large size of which does not allow resection with preservation of the limb, isolated regional perfusion (IRP) of the limb is considered as one of the effective treatment options.Aim. To evaluate the long-term outcomes of IRP with melphalan under conditions of hyperthermia for treatment of locally advanced STS of the extremities.Materials and methods. We conducted a prospective cohort clinical study that included 42 patients with STS of the extremities. All patients underwent IRP with melphalan, in one case – in combination with tumor necrosis factor alpha. Additional lymph node dissection was performed in 8 cases (19%). The 5-year overall survival was estimated by the Kaplan-Meier method.Results. The median age of the patients was 50 years (from 24 to 80 years), women predominated – 32 (76%). STS of the upper limb was diagnosed in 14 patients (33%), of the lower limb in 28 (67%). G3 grade was verified in 34 (81%) patients, in the rest – G2. Most patients had a recurrent tumor – in 34 (81%) cases. All patients received previous treatment: surgery in combination with chemotherapy and / or radiation therapy – 36 (86%), chemotherapy alone – 2 (5%), surgery alone – 4 (9%) patients. Within 5 years, tumor recurrence developed in 20 (48%) patients, amputation was performed in 10 (24%) patients, distant metastases were diagnosed in 4 (10%) patients. The mean time to relapse after IPC was 9.3 ± 3.5 months. Overall survival at 1, 2, 3, 4, and 5 years was 98%, 88%, 86%, 74%, and 67%, respectively.Conclusion. IRP under conditions of hyperthermia with melphalan is an effective method for the treatment of STS of the extremities: the overall 5-year survival rate is 67% with a low rate of amputations and metastasis.
DUKUNGAN KELUARGA BERHUBUNGAN DENGAN TERHADAP TAHAPAN BERDUKA ( STAGE OF GRIEFING ) PASIEN DIABETES MELITUS DI PUSKESMAS SENDURO LUMAJANG
Authors: Kurnia Agung Yoga Sandhi  
Published: August 2023

Seseorang yang menderita penyakit Diabetes Melitus dapat mengalami reaksi berupa perubahan biologi, psikologi, sosial,reaksi ini akan berakibat penurunan kwalitas kesehatan yang akan menambah memperburuknya keadaan kesehatanya,untuk itu masalah yang diderita selain diabets adalah perubahan tahapan berduka,respon tahapan ini sangat mempengaruhi penerimaan terhadap penyakit ini, penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga terhadap tahapan berduka (stage of griefing)pasien diabetes militus di Puskesmas Senduro Lumajang.
Jenis penelitian ini menggunakan metode “analitik korelasional” dengan desain penelitian cross sectional,sampel penelitian ini diambil dengan metode Accident Sampling dengan populasi 79 pasien dan sampel 66 pasien diabetes militus.responden di dapat dipoli umum puskesmas senduro lumajang,yang dilaksanakan pada tanggal 27 Februari 2023 – 20 Maret 2023.Dengan menggunakan kuisoner Hensarling Diabetes Family Support Scale (HDFSS) dan the acceptance of disease and impairment (ADIQ) yang telah di validasi dan reabilitasi. serta dianalisis menggunakan SPSS dengan uji rank spearman rho
Data didapat,dengan hasil penelitian menunjukan dukungan keluarga sebanyak 41 (62.1%) responden,sedangkan pada tahapan berduka di fase penerimaan sebanyak 45 (68,2%) responden hasil penelitian menunjukan dukungan keluarga terhadap tahapan berduka (stage of griefing) pasien diabetes militus dengan nilai (p-value 0,000) dengan nilai correlation coefficient sebesar (+0.867).
Seseorang yang telah terdiagnosis penyakit diabetes dapat mengalami berbagai tahapan berduka selama hudupnya. keluarga menjadi support sistem bagi pasien diabetes militus dan untuk instansi pemerintah bisa sebagai bahan pertimbangan pelayanan dan pengembangan program peningkatan peran keluarga dalam upaya menangani tahapan berduka penderita yang pasti akan dialami,sehingga bisa meningkatkan derajat kesehatan penderita yang berkelanjutan.
Asuhan Keperawatan pada Pasien Halusinasi Pendengaran dengan Penerapan Terapi Generalis
Authors: Arni Nur Rahmawati  , Luthfiana Dewi  
Published: August 2023

Introduction: Halusinasi pendengaran merupakan distorsi persepsi palsu dimana pasien gangguan jiwa mendengar bisikan atau suara-suara yang tidak nyata dan meresponnya. Gangguan halusinasi dapat dikontrol dengan terapi generalis SP 1-4: mengenalkan halusinasi dan menghardik, minum obat, bercakap-cakap dan melakukan aktivitas terstruktur.
Objectives: Tujuan penelitian ini adalah untuk memberikan asuhan keperawatan pada pasien dengan gangguan persepsi sensori: halusinasi pendengaran.
Methods: Metode yang digunakan adalah studi kasus melalui wawancara, observasi fisik dan dokumentasi. Partisipan yang digunakan dalam implementasi asuhan keperawatan jiwa adalah Sdr. A dengan gangguan halusinasi pendengaran di Wisma Antareja RSJ Prof. Dr. Soerojo Magelang. Analisis data yang digunakan dengan melakukan evaluasi penerapan generalis strategi pelaksanaan halusinasi.
Results: Hasil studi kasus menunjukkan bahwa pasien mampu mengidentifikasi masalah halusinasi yang dialami dan mampu mengontrol halusinasi.
Conclusions: Terapi generalis pada pasien halusinasi dapat membantu pasien mengenali halusinasinya sampai pada tindakan mengontrol halusinasi. Terapi generalis sebaiknya dilakukan rutin oleh perawat kepada pasien.
Síndrome de Body Stalk. Reporte de caso.
Authors: Hoyos-Belalcázar Diana Marcela , Quilindo Catalina Isabel , Narvaez-Chávez John Edgar 
Published: August 2023

Objetivo: Reportar un caso de síndrome de Body Stalk en una gestante con antecedente de consumo de sustancias psicoactivas y sífilis gestacional.
Descripción de caso: Presentamos un caso de síndrome de Body Stalk diagnosticado a las 10 semanas de edad gestacional. El embrión presentaba múltiples defectos característicos del síndrome, incluyendo defectos de la pared abdominal y de extremidades inferiores. El síndrome de Body Stalk es un defecto congénito poco frecuente con mal pronóstico.
Conclusiones: El síndrome de Body Stalk es un defecto congénito severo el cual es incompatible con la vida. El diagnóstico prenatal ultrasonográfico ayuda a definir la conducta obstétrica y disminuye el riesgo de morbilidad materna.
Analisis Pengendalian Kualitas Bibit Sawit Dengan Menggunakan Metode Fault Tree Analysis (FTA) dan Metode Failutre Mode Effect Analysis (FMEA) di PT. Kapuas Sawit Sejahtera
Authors: Ridwan Wahyuniati , Widiastuti Retno , Nurhayati Emmy 
Published: August 2023

Quality is an important factor related to company performance. This quality control is applied in various companies, one of which is PT. Kapuas Sawit, Sejahtera which has a problem with palm seed defects that cannot be overcome. This study aims to identify the factors causing defects in palm seed products. In addition, to provide proposed improvements that can improve the quality of palm seed products. This study uses descriptive qualitative through data analysis of the Fault Tree Analisys (FTA) method and the Failur Mode and Effect Analysis (FMEA) method. Fault Tree Analisys (FTAs). The results of the study through the FTA method obtained the factors causing dwarf defects, defects attacked by diseases, and defects attacked by pests are human, method, and environmental. Through the FMEA method, the proposed improvements made are to carry out cultivation with intensive stature, improve rest time by implementing a short rest system to reduce the impact of the workload, and provide boiler ash before and during the dry season. Researchers hope that the company will further improve the quality of oil palm seeds and that subsequent researchers can develop this research.
Keywords: Quality of Oil Palm Seeds, Fault Tree Analisys, Failure Mode and Effect Analysis
Pengaruh Pernikahan Dini terhadap Tingkat Pertumbuhan Stunting di Kelurahan Terjun Kecamatan Medan Marelan
Authors: Putri Dewi Khadijah Dinda , Hanum Khairunisa , Lubis Nadratul Hasanah , Fazrah Yasmi , Saleh Syarbaini 
Published: August 2023

The purpose of this study was to determine the effect of early marriage on stunting growth rates in Kelurahan Terjun, Medan Marelan District. The research method used is an analytical observational method with a cross-sectional research design. From the results of this study, further research is still needed to overcome and prevent stunting events at the Waterfall Health Center, Medan Marelan District in order to create a stunting prevention program from its risk factors.
Keywords: Early Marriage, Growth, Stunting
Pengaruh Brand Ambassador NCT Dream dan Social Media Marketing terhadap Purchase Intention dengan Brand Awareness sebagai Variable Intervening:
Authors: Azizah Afiaty Caesaria , Welsa Henny , Hutami Lusia Tria Hatmanti 
Published: August 2023

This study aims to find out how much influence NCT DREAM Brand Ambassador and Social Media Marketing have on Purchase Intention with Brand Awareness as an intervening variable (Case Study on Lemonilo Product Consumers in Yogyakarta City). The population in this study was all consumers of Lemonilo products. The sample in this study was 100 respondents using the Nonprobability Sampling technique used is purposive sampling where the researcher selects the sample subjectively with certain considerations. This data was taken using a questionnaire through a google form, after the result questionnaire was collected, data processing and analyzing data was carried out using the IBM SPSS version 22 application. The results of this study show that Brand ambassadors have a positive and significant effect on brand awareness. Social media marketing has a positive and significant effect on brand awareness. Brand awareness has a significant and positive effect on purchase intention. Brand ambassadors have a significant and positive effect on purchase intention. Social media marketing has a positive and significant effect on purchase intention.
]Keywords: Brand Ambassador, Brand Awareness, Social Media Marketing, Purchase Intention
Peran Gaya Kepemimpinan dan Motivasi Dalam Meningkatkan Kinerja Karyawan pada PT Jsky Energy Indonesia
Authors: Sari Ayu Novita , Sari Mega Puspita 
Published: August 2023

This study aims to determine the role of leadership style and motivation in improving employee performance at PT Jsky Energy Indonesia. This research uses qualitative descriptive research methods. Respondents in this study were 10 respondents consisting of contract and daily employees consisting of leaders, raw materials, QC and operators of PT Jsky Energy Indonesia. The data collection methods used are observation, interviews and documentation. The data collected is analyzed descriptively by reducing data, presenting data, and drawing conclusions. The results of this study indicate that the Role of Leadership Style and Motivation in Improving Employee Performance of PT. Jsky Energy Indonesia is very good as evidenced by unhurried decision making and through consideration, leaders always motivate employees, leaders often communicate with employees, leaders give instructions or orders to employees so that employees can work properly and correctly, leaders always carry out their duties and obligations seriously and responsibly, leaders can control their emotions, leaders not only see production progress from reports but go directly to the field, leaders have a future orientation so that PT. Jsky Energy Indonesia always innovates to create new quality products, leaders have a high level of ideals so that PT. Jsky Energy Indonesia always strives to be a better company than its competitors, leaders have task orientation and task seriousness with frequent leaders always controlling and ensuring conditions in the field, efforts to progress made by leaders by providing innovations in improving product quality, leaders have work diligence by often doing work outside office hours, always ensuring the state of production is running well, leaders have good relationships with coworkers, and leaders can utilize their time well and maximally.
Keywords: Leadership Style, Motivation, Employee Performance