bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns and drivers of vector-borne microparasites in a classic metapopulation
Authors: Mackenzie Laura S. , Lambin Xavier , Bryce Emma , Davies Claire L. , Hassall Richard , Shati Ali A. M. , Sutherland Chris , Telfer Sandra E. 
Published: July 2023

AbstractMany organisms live in fragmented populations, which has profound consequences on the dynamics of associated parasites. Metapopulation theory offers a canonical framework for predicting the effects of fragmentation on spatiotemporal host–parasite dynamics. However, empirical studies of parasites in classical metapopulations remain rare, particularly for vector-borne parasites. Here, we quantify spatiotemporal patterns and possible drivers of infection probability for several ectoparasites (fleas, Ixodes trianguliceps and Ixodes ricinus) and vector-borne microparasites (Babesia microti, Bartonella spp., Hepatozoon spp.) in a classically functioning metapopulation of water vole hosts. Results suggest that the relative importance of vector or host dynamics on microparasite infection probabilities is related to parasite life-histories. Bartonella, a microparasite with a fast life-history, was positively associated with both host and vector abundances at several spatial and temporal scales. In contrast, B. microti, a tick-borne parasite with a slow life-history, was only associated with vector dynamics. Further, we provide evidence that life-history shaped parasite dynamics, including occupancy and colonization rates, in the metapopulation. Lastly, our findings were consistent with the hypothesis that landscape connectivity was determined by distance-based dispersal of the focal hosts. We provide essential empirical evidence that contributes to the development of a comprehensive theory of metapopulation processes of vector-borne parasites.
Redescription and new record of Paracapillaria (Ophidiocapillaria) najae (Nematoda: Trichuroidea) in the monocled cobra Naja kaouthia from central Thailand: morphological and molecular insights
Authors: Charoennitiwat Vachirapong , Chaisiri Kittipong , Ampawong Sumate , Laoungbua Panithi , Chanhome Lawan , Vasaruchapong Taksa , Tawan Tanapong , Thaenkham Urusa , Ratnarathorn Napat 
Published: July 2023

AbstractThe parasitic nematode Paracapillaria (Ophidiocapillaria) najae De, 1998, found in the Indian cobra Naja naja is redescribed and re-illustrated in the present study. The monocled cobra Naja kaouthia was discovered to be a new host for this parasite in central Thailand. A comprehensive description extending the morphological and molecular characteristics of the parasites is provided to aid species recognition in future studies. The morphometric characters of 41 parasites collected from 5 cobra specimens are compared with those described in the original studies. Phylogenetic analyses using mitochondrial cytochrome c oxidase subunit 1 and nuclear 18S ribosomal RNA genes were performed to provide novel information on the systematics of P. najae. Similar characteristics were observed in the examined nematode samples, despite being found in different hosts, confirming their identity as P. najae. The molecular genetic results support the species status of P. najae, indicating P. najae is well defined and separated from other related nematode species in the family Capillariidae. Morphological descriptions, genetic sequences, evolutionary relationships among capillariids and new host and distribution records of P. najae are discussed. Paracapillaria najae specimens found in the Thai cobra had some morphological variation, and sexual size dimorphism was also indicated. Paracapillaria najae was found to infect various cobra host species and appeared to be common throughout the Oriental regions, consistent with its hosts' distribution.
Towards a theology of the Psalm titles: The Davidic voice and the totus Christus
Authors: Balfour Rory J. 
Published: July 2023

AbstractThis article explores the ways in which the thirteen ‘biographical superscriptions’ which are found throughout the Psalter contribute to the blending of the Davidic voice which they invoke and the corporate voice of the community which receives them. It suggests that by receiving these thirteen Psalms, the canonical community enters an intensive identification with David and participates in the Davidic life and experience. Once this is established, the discussion turns to examine these insights in a Christian theological context in conversation with Augustine's totus Christus principle. It is suggested that the hermeneutical situation created by the biographical superscriptions provides a way for the totus Christus principle to be re-invoked in contemporary interpretation.
Schleiermacher's reduction of incarnation to deification
Authors: Michelson Jared 
Published: July 2023

AbstractSchleiermacher's theological champions like Kevin Hector contend that his Christology is ‘high’ and is Chalcedonian in spirit. I offer a number of objections to this view, suggesting that Schleiermacher offers a distinctive, early modern account of Christ as a uniquely deified redeemer but not of Christ as the uncreated God. This raises some surprising questions for the dogmatic relation of Christology, soteriology and anthropology.
The aftermath of ballot box success and failure: evidence from land preservation referendums
Authors: Gill Carrie , Lang Corey , Pearson-Merkowitz Shanna 
Published: July 2023

AbstractState and local governments put hundreds of referendums on the ballot each year. Often, they pass but sometimes they fail. What happens after a successful or failed attempt at the ballot box? Do advocates go back to voters with another request? And if they do, do they tend to succeed? We employ a regression discontinuity empirical framework to causally estimate referendum dynamics in the arena of land conservation. Our results suggest municipalities where a referendum just barely fails hold about 0.5 more referendums and pass about 0.28 more referendums than municipalities that just barely pass, meaning initial defeat is often reversed. We also investigate whether strategic changes are made in election approaches for those that try again. We find no evidence of systematic patterns in strategic revisions for municipalities that fail their first referendum. However, when revisions are made, our evidence suggests that voters appear to respond positively.
The (im)mobilities of COVID-19 in later life: burning and building generational bridges
Authors: Tinkler Penny , Fenton Laura , Lang Luciana 
Published: July 2023

AbstractThe COVID-19 pandemic foregrounded a numerical conception of age. Many of the targets of proposals to introduce age-specific restrictions are members of the ‘baby boomer’ generation, a generation that is widely recognised as having a youthful approach to ageing. Attending to arguments that baby boomers are a ‘bridging’ generation – i.e. they share cultural orientations with both preceding and succeeding generations – we argue that ‘bridging’ is a dynamic practice. Drawing on repeat interviews with 45 ‘war baby’ and baby boomer women conducted prior to the pandemic and shortly after the first national lockdown, the paper demonstrates how lockdown restrictions brought to light older women's relationships to, and investments in, spatial mobilities. We focus on how they experienced and understood (im)mobilities in three realms: home life, going places and social connection. Pre-pandemic, mobilities in each of these realms had been important to how the women established youthfulness and resisted being seen as ‘old’; mobilities helped older women ‘bridge’ with younger adult generations. This bridging was undermined practically, symbolically and discursively by their experiences of the lockdown, with profound consequences for perceptions of their ageing. Restrictions on spatial mobilities created conditions for older women to reassess and narrate the social world in generational terms. Their narratives provide an illuminating case study of the complex ways that generational cohort shapes experiences and self-understandings. We argue that the capacity of baby boomers to ‘bridge’ dynamically is a legacy of their youth.
Masculinity, poverty and body image among older men in Tanzania: connecting intersectionality and Bourdieu's theory of practice
Authors: Rutagumirwa Sylivia Karen , Bailey Ajay 
Published: July 2023

AbstractUntil now, the body image literature has largely ignored older men. In particular, little is known about how older men perceive and experience their ageing bodies, despite the importance of the body to men's practice of masculinity and their position within gendered hierarchies. Addressing this gap in the research, we conducted 15 in-depth interviews and ten focus group discussions (N = 60) with older men aged 60–82 years. Drawing upon the intersectionality approach and Bourdieu's theory of practice, we examined how older men with low socio-economic status give meaning to their ageing bodies in relation to ideals of masculinity. The findings suggest that body strength is vital capital for older men with low socio-economic status, and that changes in their bodies as they age affect their ability to actualise themselves as ‘real’ men and undermine their sense of masculinity. The inability to live up to masculine ideals left most of these men feeling inadequate and ashamed. The findings further reveal that stress caused by ageing bodies, exacerbated by older men's socio-economic conditions, constituted a threat to their survival and overall wellbeing. Interventions should take older men's perceptions of and adaptations to the ageing body into account. In addition, when designing interventions for older men, practitioners should consider the socio-economic and cultural context in which older men are embedded. Particularly important is a gender-transformative intervention that raises awareness of negative masculine norms.
Negotiating Experiences of Belonging Alongside Age-Related Life Transitions
Authors: Fortune Darla , Weisgarber Brittany 
Published: July 2023

AbstractBelonging is a pervasive human need that is vital to our well-being as we age. Ageist attitudes, stereotyping, and life transitions tend to jeopardise older adults’ experiences of belonging. Although community involvement can lead to the development of social relationships that support belonging in older adulthood, little is known about how belonging is perceived and experienced by older adults. The purpose of this article is to share findings from research conducted with members of a community centre for people 50 years of age and older who shared their perceptions and experiences of belonging. Findings highlight the ways that age-related life transitions affect experiences of belonging. Findings also reveal that features of a belonging experience include feeling worthwhile, being welcomed and accepted, having opportunities for connection, and seeking to belong. We draw from these findings to suggest ways to enhance belonging for older adults.
Timing and type of adverse life events: Impact on substance use among high-risk adolescents
Authors: Zarchev Milan , Kamperman Astrid M. , El Marroun Hanan , Bloemendaal Anthony , Mulder Cornelis L. , Hoogendijk Witte J.G. , Grootendorst-van Mil Nina H. 
Published: July 2023

AbstractA robust association has been reported between childhood adverse life events (ALEs) and risky substance use in adolescence. It remains unclear, however, what the impact of type and timing of these ALEs is. We investigated the association between ALEs and substance use in adolescents. ALEs were operationalized as broad (e.g., moving, parental divorce, family sickness) or physically threatening (physical and/or sexual abuse). First, we examined lifetime ALEs, followed by an investigation into their timing. The sample consisted of 909 adolescents (aged 12–18 years) from a cohort oversampled on high levels of emotional and behavioral problems. The primary caregiver indicated which ALEs each adolescent experienced across their lifetime. Adolescents self-reported on number and frequency of substances used. Poisson and ordinal regression models were used to model the associations. The associations between lifetime ALEs and a substance used were observed only for physical ALEs (incidence rate ratio 1.18 [1.03, 1.35], p = 0.02). When investigating timing, physical ALEs after the age of 12 predicted number of substances used (IRR 1.36 [1.13, 1.63], p < .001). Recent ALEs (occurring after age 12) seem to have considerable impact on substance use. Alcohol and drugs as a coping mechanism were considered a plausible explanation for the results.
‘They’re all individuals, none of them are on the same boat’: barriers to weight management in general practice from the rural nurse perspective
Authors: Norman Kimberley , Burrows Lisette , Chepulis Lynne , Mullins Hilde , Lawrenson Ross 
Published: July 2023

Abstract

Aim:
To explore nurses’ experiences with, and barriers to, obesity healthcare in rural general practice.

Background:
Obesity is a significant health risk worldwide, which can lead to many other physical and psychosocial health issues that contribute to a poor quality of life. Primary care is considered the most suitable context to deliver obesity management healthcare across the world, including New Zealand, which reportedly has 34% of all adults (and 51% Indigenous Māori) classed as obese. Nurses in primary care have a significant role in the multidisciplinary team and deliver obesity healthcare in general practice contexts. Yet, there is little focus on the nurse perspective of weight management, specifically in rural areas where medical staff and resources are limited, and obesity rates are high.

Methods:
This was a qualitative research design. Semi-structured interviews with 10 rural nurses from indigenous and non-indigenous health providers were analyzed guided by Braun and Clarke (2006) approach to thematic analysis.

Findings:
Three themes were identified: limitations of a nurse role; patient-level barriers; and cultural barriers. Nurses reported experiencing significant barriers to delivering effective weight management in their practice due to factors outside the scope of their practice such as patient-level factors, social determinants of health, rural locality restrictions, and limitations to their role. While this study highlights that practice nurses are versatile with an invaluable skill repertoire, it also demonstrates the near impossibility for rural nurses to meet their rural patient’s complex weight management needs, as there are many social determinants of health, sociocultural, and rural locality factors acting as barriers to effective weight management. Nurses experienced a lack of systemic support in the form of time, resources, funding, and effective weight management referral options. Future investigation should look to address the unique rural weight management healthcare needs that experience many barriers.
Learnability with PAC Semantics for Multi-agent Beliefs
Authors: MOCANU IONELA G. , BELLE VAISHAK , JUBA BRENDAN 
Published: July 2023

AbstractThe tension between deduction and induction is perhaps the most fundamental issue in areas such as philosophy, cognition, and artificial intelligence. In an influential paper,Valiantrecognized that the challenge of learning should be integrated with deduction. In particular, he proposed a semantics to capture the quality possessed by the output ofprobably approximately correct(PAC) learning algorithms when formulated in a logic. Although weaker than classical entailment, it allows for a powerful model-theoretic framework for answering queries. In this paper, we provide a new technical foundation to demonstrate PAC learning with multi-agent epistemic logics. To circumvent the negative results in the literature on the difficulty of robust learning with the PAC semantics, we consider so-called implicit learning where we are able to incorporate observations to the background theory in service of deciding the entailment of an epistemic query. We prove correctness of the learning procedure and discuss results on the sample complexity, that is how many observations we will need to provably assert that the query is entailed given a user-specified error bound. Finally, we investigate under what circumstances this algorithm can be made efficient. On the last point, given that reasoning in epistemic logics especially in multi-agent epistemic logics is PSPACE-complete, it might seem like there is no hope for this problem. We leverage some recent results on the so-calledRepresentation Theoremexplored for single-agent and multi-agent epistemic logics with theonly knowingoperator to reduce modal reasoning to propositional reasoning.
Herbicide resistance in Bromus spp.: a global review
Authors: Ribeiro Victor H. V. , Barroso Judit , Brunharo Caio A. C. G. , Mallory-Smith Carol 
Published: July 2023

AbstractThis review summarizes what is currently known about herbicide resistance in Bromus spp. worldwide. Additional information on the biology and genetics of Bromus spp. is provided to further the understanding of resistance evolution and dispersal of the different species. Cases of herbicide resistance have been confirmed in Bromus catharticus Vahl., Bromus commutatus Schrad. (syn.: Bromus racemosus L.), Bromus diandrus Roth, Bromus japonicus Thunb. (syn.: Bromus arvensis L.), Bromus madritensis L., Bromus rigidus Roth (syn.: Bromus diandrus Roth ssp. diandrus), Bromus rubens L., Bromus secalinus L., Bromus sterilis L., and Bromus tectorum L. in 11 countries. Bromus spp. populations have evolved cross- and multiple resistance to six herbicide sites of action: acetyl-coenzyme A carboxylase, acetolactate synthase, photosystem II, very-long-chain fatty-acid, 5-enolpyruvylshikimate-3-phosphate synthase, and 4-hydroxyphenylpyruvate dioxygenase inhibitors. Resistance mechanisms varied from target-site to non–target site or a combination of both. Bromus spp. are generally highly self-pollinated, but outcrossing can occur at low levels in some species. Bromus spp. have different ploidy levels, ranging from diploid (2n = 2x = 14) to duodecaploid (2n = 12x = 84). Herbicide resistance in Bromus spp. is a global issue, and the spread of herbicide-resistance alleles primarily occurs via seed-mediated gene flow. However, the transfer of herbicide-resistance alleles via pollen-mediated gene flow is possible.
Limb and cardiovascular event risk in type 1 and 2 diabetic patients with peripheral artery disease
Authors: Sykora Daniel , Firth Christine , Girardo Marlene , Tseng Andrew , Wennberg Paul , Liedl David , Shamoun Fadi 
Published: July 2023

Summary: Background: Peripheral artery disease (PAD) is a risk factor for adverse limb events (LE) and cardiovascular events (CVE) that coexists with type 1 (T1) and 2 (T2) diabetes mellitus (DM). Little is known about comparative risk of LE and CVE in T1/T2 DM patients with PAD. Patients and methods: We queried our database of 40,144 patients ≥18 years old who underwent ankle brachial index (ABI) measurement from 01/1996-02/2020. We isolated T1/T2 DM patients with PAD diagnosed by ankle brachial index (ABI; low [<1.0] or elevated [>1.4]) and retrieved demographics including glycated hemoglobin (HbA1c). Primary outcomes were LE (critical limb ischemia/vascular amputation) and CVE (myocardial infarction/ischemic stroke). All-cause mortality was a secondary outcome. Multivariable Cox proportional regression yielded hazard ratios (HR) with 95% confidence intervals (CI) after adjusting for pertinent risk factors including age, hypertension, hyperlipidemia, smoking, and HbA1c. Results: Our study found 10,156 patients with PAD and DM (34% T1DM, 66% T2DM) with median follow-up time 34 mo (IQR 85 mo). T1DM patients were younger than T2DM (mean age 67 vs. 70 years), with higher median HbA1c (7.7 [IQR 1.9] vs. 6.7% [IQR 1.6]), and more prevalent hypertension, hyperlipidemia, CAD, and CKD. Antiplatelet and statin use was equivocal. Elevated ABI was more common in T1DM (47 vs. 28%). LE occurred in 23% and CVE in 12% patients. LE risk was higher in T1 than T2 DM patients (HR 1.58 [95% CI 1.44, 1.73], p<0.0001), but CVE and all-cause mortality were equivocal. These observations were preserved across ABI and HbA1c subgroup analyses. Conclusions: PAD patients with T1DM had a higher LE risk than those with T2DM, even after adjustment for glycemic control and pertinent risk factors, but CVE risk and all-cause mortality were equivocal. These data suggest a potential role for more intensive LE risk modification in PAD patients with T1DM, but further investigation is needed.
Prognostic impact of secondary versus de novo ontogeny in acute myeloid leukemia is accounted for by the European LeukemiaNet 2022 risk classification
Authors: Hochman Michael J. , Othus Megan , Hasserjian Robert P. , Ambinder Alex , Brunner Andrew , Percival Mary-Elizabeth M. , Hourigan Christopher S. , Swords Ronan , DeZern Amy E. , Estey Elihu H. , Karp Judith E. 
Published: July 2023

AbstractSecondary AML (sAML), defined by either history of antecedent hematologic disease (AHD) or prior genotoxic therapy (tAML), is classically regarded as having worse prognosis than de novo disease (dnAML). Clinicians may infer a new AML diagnosis is secondary based on a history of antecedent blood count (ABC) abnormalities in the absence of known prior AHD, but whether abnormal ABCs are associated with worse outcomes is unclear. Secondary-type mutations have recently been incorporated into the European LeukemiaNet (ELN) 2022 guidelines as adverse-risk features, raising the question of whether clinical descriptors of ontogeny (i.e., de novo or secondary) are prognostically significant when accounting for genetic risk by ELN 2022. In a large multicenter cohort of patients (n = 734), we found that abnormal ABCs are not independently prognostic after adjusting for genetic characteristics in dnAML patients. Furthermore, history of AHD and tAML do not confer increased risk of death compared to dnAML on multivariate analysis, suggesting the prognostic impact of ontogeny is accounted for by disease genetics as stratified by ELN 2022 risk and TP53 mutation status. These findings emphasize the importance that disease genetics should play in risk stratification and clinical trial eligibility in AML.
Diversification during cross-kingdom microbial experimental evolution
Authors: Kovács Ákos T 
Published: July 2023

Abstract
Experimental evolution in a laboratory helps researchers to understand the genetic and phenotypic background of adaptation under a particular condition. Simultaneously, the simplified environment that represents certain aspects of a complex natural niche permits the dissection of relevant parameters behind the selection, including temperature, oxygen availability, nutrients, and biotic factors. The presence of other microorganisms or a host has a major influence on microbial evolution that often differs from the adaptation paths observed in response to abiotic conditions. In the current issue of the ISME Journal, Cosetta and colleagues reveal how cross-kingdom interaction representing the cheese microbiome succession promotes distinct evolution of the food- and animal-associated bacterium, Staphylococcus xylosus. The authors also identified a global regulator-dependent adaption that leads to evolved derivatives exhibiting reduced pigment production and colony morphologies in addition to altered differentiation phenotypes that potentially contribute to increased fitness.