bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Platelet-Rich Plasma and other Key Factors on Hair Follicle Preservation
Authors: Thuangtong Rattapon , Chaweekulrat Pichanee , Thanomkitti Kanchalit , Triwongwaranat Daranporn , Rujitharanawong Chuda 
Published: July 2023

ABSTRACT

Background:
Hair graft preservation is an important factor that influences graft survival in hair transplantation.

Objective:
To investigate the benefits of adding platelet-rich plasma (PRP), and the effect of different storage solutions and temperatures on hair follicle preservation.

Materials and Methods:
This randomized-controlled study included 10 androgenetic alopecia patients who underwent hair transplantation. Forty-five hair grafts were collected from each patient and then randomized to 8 different culture conditions for 7 days. Hair grafts were cultured in Williams’ Medium E or Ringer’s lactate solution (RLS) at either 4°C or 37°C, and with or without 10% PRP supplementation.

Results:

In vitro hair growth in Williams’ Medium E was significantly greater than in RLS. The 37°C temperature condition was found to be significantly better than the 4°C condition. The growth of hair grafts cultured with PRP was not significance difference from those without PRP. However, immunofluorescence staining for cytokeratin 15 showed greater expression in hair graft cultured with PRP.

Conclusion:
PRP may have a beneficial effect for preserving the viability of hair grafts. Williams’ Medium E and 37°C temperature were found to be superior to RLS and 4°C relative to hair follicle growth in organ culture.
Preparation and Characterization of Capsaicin Encapsulated Polymeric Micelles and Studies of Synergism with Nicotinic Acids as Potential Anticancer Nanomedicines
Authors: Shamsheer Rawan , Sunoqrot Suhair , Kasabri Violet , Shalabi Dana , Alkhateeb Rema , Alhiari Yusuf , Ababneh Riad , Ikhmais Balqis , Abumansour Hamza 
Published: July 2023

ABSTRACT

Background/Objective/Methods:
Capsaicin micelles were prepared by the direct dissolution using the amphiphilic copolymer Pluronic P123 and advanced for substantially novel submicro-nanocytotoxicity.

Results:
Superior cytotoxicity of capsaicin loaded nanomicelles vs. both the raw capsaicin and reference cisplatin in pancreatic PANC1, breast MCF7, colorectal resistant CACO2, skin A375, lung A549 and prostate PC3 cancer cell lines were delineated. Nicotinic acid (NA) derivative 39 (2-Amino IsoNA) had antiinflammatory potential but consistently lacked antiproliferation in MCF7, PANC1 and CACO2. Besides NA derivatives 8 (5-MethylNA) and 44 (6-AminoNA) exhibited lack of antiinflammation but had comparable antitumorigenesis potency to cisplatin in PANC1 cells. Though capsaicin loaded nanomicelles exerted pronounced antiinflammation (with IC50 value of 510 nM vs. Indomethacin’s) in lipopolysacchride-induced inflammation of RAW247.6 macrophages; they lacked DPPH scavenging propensities. Free capsaicin proved more efficacious vs. its loaded nanocarriers to chemosensitize cytotoxicity of combinations with NAs 1(6-Hexyloxy Nicotinic Acid), 5(6-OctyloxyNA), 8(5-MethylNA), 12(6-Thien-2yl-NA), 13(5,6-DichloroNA) and 44(6-AminoNA) in CACO2, PANC1 and prostate PC3.

Conclusion:
Capsaicin loaded nanomicelles proved more efficacious vs. free capsaicin to chemo-sensitize antiproliferation of cotreatments with NA derivatives, 1, 5, 8, 12, 13 and 44 (in skin A375), 1, 5, 8 and 12 (in breast MCF7), and 1, 5, 12 and 44 (in lung A549).
Recommendations for enhanced primary series (third dose) COVID-19 vaccination for people with rheumatic diseases: Chapter of Rheumatologists, College of Physicians, Singapore
Authors: Xu Chuanhui , Lahiri Manjari , Santosa Amelia , Chew Li-Ching , Angkodjojo Stanley , Sriranganathan Melonie , Fong Warren , Arkachaisri Thaschawee , Suresh Ernest , Kong Kok Ooi , Lateef Aisha , Lee Tau Hong , Leong Keng Hong , Low Andrea , Tan Teck Choon , Leung Ying-Ying 
Published: July 2023

ABSTRACT

Introduction:
This review aims to provide evidence-based recommendations for an enhanced primary series (third dose) coronavirus disease 2019 (COVID-19) vaccination in people with rheumatic diseases (PRDs) in the local and regional context.

Methods:
Literature reviews were performed regarding the necessity, efficacy, safety and strategies for enhanced primary series COVID-19 vaccination in PRDs. Recommendations were developed based on evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Evidence was synthesised by eight working group members, and the consensus was achieved by a Delphi method with nine members of an expert task force panel.

Results:
Two graded recommendations and one ungraded position statement were developed. PRDs have impaired immunogenicity from the COVID-19 vaccine and are at an increased risk of postvaccine breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and poor clinical outcomes, compared to the general population. We strongly recommend that PRDs on immunomodulatory drugs be offered a third dose of the messenger RNA (mRNA) vaccine as part of an enhanced primary series, after the standard two-dose regimen. We conditionally recommend that the third dose of mRNA vaccine against SARS-CoV-2 be given at least 4 weeks after the second dose or as soon as possible thereafter. There is insufficient data to inform whether the third mRNA vaccine should be homologous or heterologous in PRDs.

Conclusion:
These recommendations that were developed through evidence synthesis and formal consensus process provide guidance for an enhanced primary series COVID-19 vaccination in PRDs.
Pembinaan Rohani Anak Sekolah Minggu Oleh Guru Pendidikan Agama Kristen Di GKII Gracia Lebak Ubah
Authors: Supardi Supardi , Lastari Yuki 
Published: July 2023

Pembinaan rohani anak Sekolah Minggu adalah salah satu komponen yang paling penting dan utama dalam gereja lokal, secara khusus di kalangan GKII Gracia Lebak Ubah, Daerah I Sintang, Wilayah II Kalimantan Barat. Pembinaan rohani anak Sekolah Minggu di GKII Gracia Lebak Ubah belum terlaksana secara maksimal. Hal itu terjadi karena gereja belum memiliki guru Sekolah Minggu secara khusus. Tujuan penelitian ini adalah untuk mengakaji serta menjelaskan upaya-upaya yang sudah dilakukan oleh Guru Pendidikan Agama Kristen dalam meningkatkan kualitas pembinaan rohani anak Sekolah Minggu di GKII Gracia Lebak Ubah, Daerah I Sintang Wilayah II Kalimantan Barat. Metode penelitian yang digunakan adalah metode kualitatif deskriptif, yakni peniliti terlebih dahulu melaksanakan riset lapangan, yakni wawancara. Dalam penilitian ini, sampel penelitian adalah Guru Pendidikan Agama Kristen, yakni sebagai pembina rohani anak Sekolah Minggu GKII Gracia Lebak Ubah, Daerah I Sintang Wilayah II Kaliman Barat. Teknik pengumpulan data yang digunakan yaitu melalui observasi (riset) lapangan, yakni wawancara. Guru Pendidikan Agama Kristen telah melaksanakan tanggung jawabnya dengan baik dalam pembinaan rohani anak Sekolah Minggu di GKII Gracia Lebak Ubah, Daerah I Sintang Wilayah II Kalimantan Barat. Peran serta Guru Pendidikan Agama Kristen dalam pembinaan rohani anak di GKII Gracia Lebak Ubah, Daerah I Sintang Wilayah II Kalimantan Barat, mengakibatkan pertumbuhan rohani anak.
Gender-Based Variation in The Academic Performance of Medical Students: A Cross-Sectional Study
Authors: Bhatti Urooj , Chohan Muhammad Nadeem , Effendi Sadia , Khidri Feriha Fatima , Ahmadani Rubina , Ghaffar Beenish 
Published: July 2023

Objective: To determine the gender-based variation in the academic performance of medical students. Methodology: This cross-sectional was carried out from January to February 2023. The students were taught two Physiology and two anatomy lectures, then after a month, the theory BCQs test of a total of 150 marks and viva-voce and OSPE of 150 marks (Total 300 marks) from the same taught topics, was conducted. The gender-based difference in the grade of students was tested using the Chi-Square test. Data analysis was done using IBM SPSS version 23.0. Results: Among (n=290) students, 117(40.34%) were male students while 173(56.66%) were the female students. Among the 117 male students, the mean±sd of total marks was 164.8 ±38.67 out of a total of 300 marks, while among the 173 female students, the mean±sd of total marks was 181.50±30.90 out of a total of 300 marks. There was a statistically significant difference in the score of students based on gender (p<0.01). Conclusion: According to this study's findings, there was notable gender discrepancies among undergraduates and female students performed much better academically than male students, as indicated by the cumulative grade point average they earned at the university. There was a statistically significant difference in the score of students based on gender (p<0.01).
ONLINE BUSINESS STRATEGY ANALYSIS THROUGH TIKTOK SHOP DIGITAL NETWORK PLATFORM MARKETPLACE
Authors: Nst Asrindah , Khairat Aldi Fasta Bhiqul 
Published: July 2023

ABSTRACT Digital marketing also facilitates communication between producers, marketers and consumers or buyers in sales activities. The phenomenon of online shopping has become something that continues to be discussed to this day. One of the app providers of online shopping features is stickers. TikTok has an interesting feature that the business shop can benefit from the use of tikTok. The research discusses how online sales can be applied on touch platforms, knowing strategies and knowing promotions that can be used. The research uses a qualitative method with a phenomenological research design to analyze the meaning of the social media platform TikTok as an online business marketing strategy. TikTok has interesting features and a comprehensive database. In addition to the increasing popularity of TikTok applications, there is a possibility that can benefit from the use of tikTok. TikTok’s objectives in the corporate world are shifting from entertainment media platforms to tools for business strategy. Tiktok has many advantages and promotional features that are very profitable to sellers and consumers, such as affiliate tags and some profitable strategies that can facilitate promotions such as trend hashtags and view ads.Keywords: Affiliation, Market Place, Tiktok Shop
Experimental Replication of a Granulated Gold Bead from an Ancient Tomb at Bat, Oman
Authors: Loepp David , Maass Alexander 
Published: July 2023

During excavation of a tomb at Bat, Oman, an unusual gold bead entirely composed of 96 granules was discovered. The bead comes from an unstratified context in the bottom of the fill of the tomb, which means that it could date anywhere during the use-life of the tomb between the 3rd and 1st Millennium BC. The technical problems surrounding the manufacture of this bead are discussed and an experimental approach is used to explore a possible method of fabrication. The results of the experiments show that a combination of autogenous welding and brazing with copper salts to construct and join the individual units of the bead was successful to produce a visual replica of the bead. The method of bead construction based on the serial production of units and sub-units also has implications on the practice and organization of goldsmithing during this era.
Chert for the Masses… Mining Archaeology in Wadi el-Sheikh. A Preliminary Report
Authors: Klaunzer Michael , Mustar Felix , Köhler E. Christiana 
Published: July 2023

The chert mines of Wadi el-Sheikh in Middle-Egypt have been well known for over 100 years now; however, archaeological research on this important raw material source is still lacking. In 2014 and 2015 the Vienna Middle Egypt Project of the University of Vienna in cooperation with the University of Virginia and the Deutsches Bergbau-Museum Bochum conducted surveys and archaeological excavations in Wadi el-Sheikh. In this article new results concerning chert mining, mining technology and the organization of labor in this desert valley are described.
Economic Geology, Mining Archaeological and Archaeometric Investigations at the Veshnaveh Ancient Copper Mine, Central Iran
Authors: Nezafati Nima , Stöllner Thomas 
Published: July 2023

The Veshnaveh ancient copper mine is located in the middle of the Orumieh-Dokhtar volcanic belt in north central Iran and is hosted by middle-upper Eocene volcanic and sedimentary rocks. The focus of this paper is the investigation of ore and rock samples from Veshnaveh using diverse geochemical and mineralogical methods including ore microscopy, scanning electron microscopy, inductively coupled plasma mass spectrometry and lead isotope analysis in order to better understand the nature of mineralization. The results were then compared with the results from the ancient metallurgical relics from some key sites in central Iran including Tappeh Sialk, Arismān, Tappeh Sarm and Jamkarān. The results show the Veshnaveh deposit is a Manto type mineralization whose ore has been possibly used from the Middle Bronze Age until the early Iron Age by surrounding communities.
Revisiting changing climatic conditions in the North Ossetia mountainous zone and their impact on erosion processes
Authors: Kuchiev S. E. , Khetagurov Kh. M. 
Published: July 2023

Currently, there are many scientific publications concerning changes in climatic conditions of individual regions, countries, continents and the entire earth as a planet. This fact has led us to consider these changes regarding their impact on the development of erosion processes in mountain conditions. The basis was the research presented in S.E Kuchiev’s PhD thesis of 1996-1998, as well as the verification of hypotheses put forward in the research on the development of erosion processes. The above mentioned required the continuation of research in the second period from 2008 to 2013. On average, 605 mm fell during the years of research, 478 mm in the first period 1996-1998, 668 mm in the second 2008-2013, and from 2 to 8 rains with an intensity of more than 20 mm fell in different years.The correlation analysis shows that with the increase in precipitation observed in recent years, there is a correlation with the amount of heavy rainfall. During the period under review, there were 27 to 48 rains with an intensity above 5 mm. In 2009 heavy rainfall was characterized mainly by an intensity of 20 to 40 mm per day, but in August 2009 and 2010, 71 and 73 mm each fell. The peak of heavy rains was noted in 2012, when in June it rained two days in a row with an intensity of 121 and 101 mm.The indicator of surface runoff has significantly increased, both in the control variant (pure steam) and in rotation crops, which can be arranged in ascending order of their erosion resistance: row crops, cereals of the continuous sowing method and perennial grasses. The research was carried out at the mountain long-term station of the SCNII–GPSH – a branch of the VNC RAS in the village of Dargavs.
Urgensi Guru BK Individual di Sekolah Dalam Meningkatkan Percaya Diri Siswa di MAN 1 Medan
Authors: Rahmadana Wulandari , Lubis Wahyu Gunawan , Srinurdayang Srinurdayang , Kamal Arsyad , Saragi Muhammad Putra Dinata 
Published: July 2023

Confidence is one of the things that is important for every individual, especially for students at school. Students who lack confidence will find it difficult to adapt to the existing environment at school. Therefore it is necessary to have follow-up from the school, namely by carrying out Guidance and Counseling teacher counseling services. This research is a type of qualitative research with a descriptive approach. Where the purpose of this research is to find out how the role of the counseling teacher plays in dealing with students who lack self-confidence. The subject of this research involves one of the counseling teachers. Data collection techniques used observation, interviews, sound recordings and documentation. From this study it was found that the method used was the face to face method, namely the individual technique of the counseling teacher directly calling the students concerned to come to the counseling room. By providing individual counseling so that students are more courageous in showing their abilities in front of their friends, and are not awkward in interacting with other Pongo pygmaeus. Basically a lack of self-confidence harms students not only through associating with a low rule attitude, but through students considering their choices in a different way. Lack of self-confidence may require attention to help ensure that students' future choices are not unnecessarily limited.
Keywords: Confidence; Individual Counseling; Student
Nikah Siri Perspektif Islam dan Kristen:
Authors: Herman⁴ Nurwinda , Pardede Hasrima Dinda , Fitriani Fitriani 
Published: July 2023

Marriage is a sacred and noble contract between a man and a woman as legal husband and wife with the aim of achieving a sakinah, mawaddah wa rahmah family, full of wisdom and mutual support. Islam advocates for marriage. Because it has a good influence on the perpetrators themselves, society and all mankind. Lately, the phenomenon of unregistered marriage has given an interesting impression. First, unregistered marriage seems to have really become a trend that is not only practiced by the general public, but also practiced by community figures who so far are often referred to by the terms kyai, dai, ustad, cleric, or other terms that mark a person's ability to study religion. (Islam). Second, unregistered marriage is often placed as an option when someone wants to be polygamous for a number of reasons.
Keywords: Siri Marriage, Islamic Perspective, Christian Perspective
Pernikahan Usia Dini Menurut Interpretasi Ayat Al-Qur’an
Authors: Matondang Husnel Anwar , Suib Muhammad , Ahbaroni Muhammad Dipa , Irwana Arini Suci , Siregar Muhajiroh Alya 
Published: July 2023

Early marriage is a common problem in every family. Given that the child is the successor and hope in the future. In fact, early marriage is increasingly happening, this is evidenced by the movement of Aisah Wedding's. There are several factors that cause many early marriages, among others; First, religious understanding that is not oriented to the best interests of the child. Second, cultural factors and traditions of the community that should not reject the application. Third, lifestyle. Fourth, poverty. Fifth, legal controversy. With the demikia of early marriage is not a solution to the problem that is happening, it is necessary to prepare the maturity of the child both theologically, physically and mentally.
Keywords: Interpretation of Verse, Early Marriage.
Konsep Kafa’ah Dalam Hukum Islam \dan Urgensinya terhadap Keutuhan Rumah Tangga Sakinah Menurut Pandangan Wahbah Az-Zuhaili
Authors: Anas Sahrun , Sutisna Sutisna , Hambari Hambari 
Published: July 2023

Kafaah in marriage is one of the factors that encourage the creation of happiness and more guarantees women's safety from husband and wife failure and more guarantees women's safety from failure or household turmoil. Based on the research results, first Jumhur ulama' explained that the concept of kafa'ah is not evaluated in terms of religion alone, but in Islamic Law, kafa'ah is measured from religious matters. The Compilation of Islamic Law (KHI) in determining the kafa'ah of marriage is more judgmental in terms of religion. Prevention of marriage can be done in certain matters that are discussed through KHI Article 60 Paragraph, second, that is prevention of marriage can be done if the prospective husband or prospective wife does not meet the requirements of marriage according to the law and Islamic law, because one of the content of the conditions of marriage is both couples are said to be valid when done in accordance with the laws of their respective religions. Third, the concept of kafa'ah of Wahbah Az-Zuhaili's view is in line with Imam Malik's opinion, which considers equality only in religion and conditions. The meaning of this condition is to be safe from the shame that makes a woman choose a candidate when she wants to get married. Wahbah Az-Zuhaili analyzed it in accordance with daily life in the community, 3) things that can affect the occurrence of harmony in the household, namely between husband and wife having compatibility. Harmony and happiness in a household is determined by the harmony of the couple.
Keywords: Kafa'ah, Islamic Law, Urgency, Household Integrity, Wahbah Az-Zuhaili
Pembagian Harta Waris terhadap Anak Angkat Perspektif Maqāşid Syarī’ah
Authors: Falah Nabilah Falah , Meidina Ahmad Rezy 
Published: July 2023

Adopted children cannot return the assets of their adoptive parents and only have rights through a mandatory will, the amount of which cannot be more than 1/3 of the assets left by their adoptive parents as stated in Article 209 paragraph (2) KHI. The fact that happened in the Bobosan sub-district there were 3 (three) cases of inheritance distribution for adopted children who received the entire adoptive parent's inheritance. This paper attempts to explain the distribution of the inheritance of adopted children that occurred in the Bobosan sub-district, Banyumas Regency from the perspective of Maqāşid Syarī'ah. This type of research is field research using an empirical juridical approach. The data source used is from primary data sources in the field by conducting in-depth interviews with the informants studied. The method used in qualitative analysis, namely describing, interpreting and hiding research data. Based on the results of the study, it can be interpreted that the division of inheritance that occurs is the need for Ḍaruriyat adopted children who live dependently living in their parents' house and continue the business of their adoptive parents. So that the family and the surrounding community consider the adopted child to be the full successor of the assets and efforts of the adoptive parents in order to prioritize the benefit of the adopted child.
Keywords: Inheritance, Adopted Children
Gambaran Trauma yang Dialami Anak Korban Perceraian
Authors: Sinaga M. Harwansyah Putra , Putri Miftahul Hasana , Munte Rohimatun Fadilah , Hasibuan Fitri Hariani 
Published: July 2023

This study aims to determine the types of trauma experienced by adolescents due to parental divorce and what children of divorce victims do to overcome the trauma of parental divorce. This research uses a qualitative descriptive approach with a case study type of research. Data collection was carried out by interviews and questionnaires. The data analysis technique used is the Miles and Huberman analysis model, namely data reduction, data presentation, and drawing conclusions. The results of this study explain that the impact of divorce on children depends on parents' understanding of children's feelings and the parenting style provided. However, parental divorce greatly impacts the psychology of children who will experience trauma from parental divorce, such as children who will feel lonely over parental separation, fear of building a household relationship, and hatred that comes to one of the parties that causes divorce. In dealing with the trauma experienced by children who are victims of divorce, namely by telling the problems they face to people they trust, and telling the problems, children will feel cared for and feel loved, then by motivating themselves by doing activities that help to overcome the trauma they are experiencing. Because by doing fun activities, you will forget about the problems you are facing and will accept your own situation.
Keywords: Types of Trauma, Overcoming Trauma, Divorce, Trauma