bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transformation Management and Sustainability Performance: On the Importance of the Enabling and Controlling Uses of Management Control Systems
Authors: Hasu Emmi , Saunila Minna , Ukko Juhani 
Published: January 2025

ABSTRACTThe purpose of this study is to investigate how transformation management affects the sustainability performance of companies and whether the enabling and controlling uses of management control systems (MCSs) mediate the relationship between a company's transformation management and sustainability performance in small‐ and medium‐sized enterprises (SMEs). The analysis revealed that the controlling use of MCSs strongly advances transformation management actions toward higher sustainability performance, while no mediating effect was found when examining the enabling use of MCSs between the same connection. The findings contribute to the discussion on the relationship between transformation management and sustainability performance. The analysis also provides novel theoretical and practical insights into the role of enabling and controlling uses of MCSs in facilitating the transformation toward higher sustainability performance.
Microplastic Materials for Inhalation Studies: Preparation by Solvent Precipitation and Comprehensive Characterization
Authors: Santizo Katherine Y. , Mangold Hannah S. , Mirzaei Zeynab , Park Hyoungwon , Kolan Rajkumar Reddy , Sarau George , Kolle Susanne , Hansen Tanja , Christiansen Silke , Wohlleben Wendel 
Published: January 2025

AbstractAssessing the inhalation hazard of microplastics is important but necessitates sufficient quantity of microplastics that are representative and respirable (<4 µm). Common plastics are not typically manufactured in such small sizes. Here, solvent precipitation is used to produce respirable test materials from thermoplastics polyurethane (TPU), polyamide (PA‐6), polyethylene terephthalate (PET), and low‐density polyethylene (LDPE). Complementary methods verified that the desired size range is achieved both in number metrics and in mass metrics. To assess if the test materials are representative of their original plastic, a range of molecular properties, particle properties, and impurities are characterized: chemical composition, molecular weight, crystallinity, molecular mobility, density, surface charge, surface reactivity, particle size in mass and number metrics, particle shape, endotoxin content, and solvent content. The test materials obtained by precipitation are compared to commercial granules as references, and to alternative test materials obtained by other synthesis routes from LDPE, TPU, PET, PA‐6, polystyrene (PS), and polyvinylchloride (PVC). Charge and surface reactivity of the precipitated test materials are low. Due to storage in water, microbial contamination needed to be monitored. For PET, PA‐6, and TPU, the test materials are considered as representative and fit for purpose, whereas the inherent hydrophobicity of LDPE imposed strong aggregation.
Non‐Volatile Multifunctional Dipole Molecules Enable 19.2% Efficiency for Printable Mesoscopic Perovskite Solar Cells
Authors: Xu Weiqiang , Zhang Yang , Huang Yu , Tao Ying , Wang Jinjiang , Liu Wenfeng , Wang Dongjie , Zhang Zheling , Xiong Jian , Zhang Jian 
Published: January 2025

AbstractDipole molecules (DMs) show great potential in defect passivation for printable mesoscopic perovskite solar cells (p‐MPSCs), although the crystallization process of p‐MPSCs is more intricate and challenging than planar perovskite solar cells. In this work, a series of non‐volatile multifunctional DMs are employed as additives to enhance the crystallization of perovskites and improve both the power conversion efficiency (PCE) and stability of the devices. This enhancement is achieved by regulating the side groups of benzoic acid molecules with the electron‐donating groups such as guanidine (─NH─C(═NH)─NH2), amino (─NH2) and formamidine (─C(═NH)─NH2). DMs form hydrogen bond interactions with the organic cations of perovskite and establish electrostatic interactions with PbI64−. The synergistic effect of these interactions suppresses PbI2 formation, enhances perovskite film crystalline quality, reduces perovskite crystal defect density, mitigates non‐radiative recombination, and effectively enhances carrier transfer and extraction efficiency. Furthermore, the incorporation of DMs leads to a reconstruction of the perovskite film surface energy level, thereby enhancing hole extraction efficiency at the perovskite/carbon electrode interface. The optimized p‐MPSCs achieve a PCE of 19.23%. The unencapsulated device demonstrates promising long‐term storage stability, retaining 91% of the original PCE after 1440 h of aging at 40 ± 5% relative humidity and 30 ± 5 °C.
Urbanisation‐driven shifts in fog patterns and fog hole formation in the Indo‐Gangetic Plain
Authors: K Lal Anie , Mohan Manju , Kunchala Ravi Kumar , Das Chiranjit 
Published: January 2025

AbstractRecent studies indicate a global decline in fog occurrences, particularly in urban areas. This study investigates fog trends across the Indo‐Gangetic Plain, focusing on the impact of urbanisation using long‐term ground and satellite data. Despite a general increase in fog frequencies elsewhere, we find a notable decline in dense fog occurrences in the megacity Delhi. Satellite data reveal that expanding fog holes over major urban areas strongly correlate with the underlying urban and built‐up areas. These findings highlight the substantial role of urban expansion in altering fog patterns, with broad implications for aviation and other sectors reliant on accurate fog prediction.
Intelligence is not deception: from the Turing test to community-based ascriptions
Authors: Pantsar Markus 
Published: January 2025

Abstract
The Turing test has a peculiar status in the artificial intelligence (AI) research community. On the one hand, it is presented as an important topic in virtually every AI textbook, and the research direction focused on developing AI systems that behave in human-like fashion is standardly called the “Turing test approach”. On the other hand, reports of computer programs passing the Turing test have had relatively little effect. Does this mean that the Turing test is no longer relevant as a test, doomed to be a theoretical notion with little connection to AI practice? In this paper, I argue that there is one problem in particular with common traditional versions of the Turing test, namely their focus on deception. The criterion for passing the Turing test is standardly connected to an AI system’s ability to deceive the interrogator about its identity. But why should we connect intelligence to the ability deceive? Here I present a revised version of an intelligence test that is not based on deception. In what I call the Community-based intelligence test (CBIT), an AI is introduced to a community of human subjects. If after a sufficient number of interactions within that community the humans are not able to identify the AI system as a computer, it is considered to have passed CBIT. I discuss whether that should be enough to ascribe intelligence to the AI, and if not, what more would be needed?
Volumes of components of Lelong upper level sets II
Authors: Su Shuang , Vu Duc-Viet 
Published: January 2025

Abstract
Let X be a compact Kähler manifold of dimension n, and let T be a closed positive (1, 1)-current in a nef cohomology class on X. We establish an optimal upper bound for the volume of components of Lelong upper level sets of T in terms of cohomology classes of non-pluripolar self-products of T.
Minimisation of 2-coverings of genus 2 Jacobians
Authors: Fisher Tom , Liu Mengzhen 
Published: January 2025

Abstract
An important problem in computational arithmetic geometry is to find changes of coordinates to simplify a system of polynomial equations with rational coefficients. This is tackled by a combination of two techniques, called minimisation and reduction. We give an algorithm for minimising certain pairs of quadratic forms, subject to the constraint that the first quadratic form is fixed. This has applications to 2-descent on the Jacobian of a genus 2 curve.
Lutetium-177 PSMA radioligand therapy in taxan-naive first- and second-line metastatic castration resistant prostate cancer after first-line ARPI therapy
Authors: Wenzel Mike , Hoeh Benedikt , Siech Carolin , Koll Florestan , Humke Clara , Groener Daniel , Steuber Thomas , Graefen Markus , Maurer Tobias , Banek Severine , Chun Felix K. H. , Mandel Philipp 
Published: January 2025

Abstract

Purpose
Lutetium-177 Prostate-specific membrane antigen (Lu-PSMA) radioligand therapy is EMA-approved for metastatic castration resistant prostate cancer (mCRPC) after androgen receptor pathway inhibition (ARPI) and taxan-based chemotherapy. However, its effect in taxan-naïve patients is under current investigation.

Methods
We relied on the FRAMCAP database to elaborate Lu-PSMA therapy outcomes of progression-free (PFS) and overall (OS) in taxan-naïve mCRPC patients after previous ARPI treatment. Comparison was made against current standard of care with ARPI or docetaxel, irrespective of the previous used staging modality.

Results
Of 269 patients, 11% received Lu-PSMA in first/second-line mCRPC vs. 57% ARPI vs. 33% docetaxel. Mostly no significant baseline differences between Lu-PSMA and ARPI patients were observed, while Lu-PSMA patients were significantly older, received less systematic treatments and ECOG1-2 proportions were higher, relative to docetaxel patients. In PFS (13.3 vs. 8.2 months, hazard ratio [HR]: 0.70, p = 0.16) and OS analyses (68.9 vs. 39.1 months, HR: 0.64, p = 0.2), Lu-PSMA was numerically more favorable than ARPI. In additional multivariable Cox regression models, Lu-PSMA was significant better regarding PFS and OS, relative to ARPI (both p < 0.05). Compared to docetaxel, also significant better PFS (13.3 vs. 8.1 months, HR: 0.46) and OS (68.9 vs. 27.3 months, HR: 0.34, both p < 0.01) was observed for Lu-PSMA treatment. The OS advantage was also observed after multivariable adjustment (p < 0.01).

Conclusion
This retrospective single-center study including a substantial proportion of patients with treatment preference for Lu-PSMA suggests that Lu-PSMA therapy provides significantly more favorable PFS and OS outcomes in taxan-naïve mCRPC patients after previous ARPI treatment, relative to ARPI or docetaxel treatment and may be considered as an early mCRPC treatment option.
Isolated inflammatory involvement of the occipital artery in giant cell arteritis and polymyalgia rheumatica: findings from a retrospective analysis and the critical role of MRI in diagnosis
Authors: Guggenberger Konstanze V. , Riedling Lukas , Kern Daria , Werner Rudolf A. , Vogt Marius L. , Fröhlich Matthias , Schmalzing Marc , Pham Mirko , Bley Thorsten A. 
Published: January 2025

Abstract

Background
Diagnosis of Giant Cell Arteritis (GCA) and Polymyalgia rheumatica (PMR) may be challenging as many patients present with non-specific symptoms. Superficial cranial arteries are predilection sites of inflammatory affection. Ultrasound is typically the diagnostic tool of first choice supplementary to clinical and laboratory examination. Inflammation of temporal arteries can be detected sonographically with high reliability. However, due to the vessel’s course and location, occipital arteries evade sonographic detectability.

Objective
The aim of our study was to evaluate the infestation pattern of superficial cranial arteries in GCA and PMR patients with special focus on the occipital arteries.

Methods
90 treatment-naïve patients with clinically and/or histologically proven GCA and/or PMR (51 GCA, 20 PMR, 10 GCA-PMR) were included in the study. All patients underwent contrast-enhanced, fat-suppressed, high-resolution black blood 2D T1-weighted spin echo imaging at 3T MRI. Images were read by three different readers independently. Temporal and occipital arteries were assessed regarding vasculitic affection. Circumferential mural hyperenhancement and thickening of the vessel wall ≥ 600 μm was considered positive for vasculitis.

Results
9/90 (10%) of all patients revealed inflammatory changes of the occipital artery only. Prevalence of isolated inflammatory affection of occipital artery was even higher in the GCA subgroup with 7/51 (14%) patients.

Conclusion
14% of GCA patients and 10% of GCA-PMR patients present with signs of inflammation of the occipital artery only. Since the occipital artery is not accessible to routine ultrasound examination, MRI renders incremental value in the diagnosis of GCA and PMR patients.
A hypocaloric protein-rich diet before metabolic surgery improves liver function in patients with obesity and diabetes
Authors: Krönert Natalie , Moulla Yusef , Lange Undine Gabriele , Blüher Matthias , Linder Nicolas , Fuhrmann Alexander , Busse Harald , Linder Anna , Karlas Thomas , Wiegand Johannes , Morgenroth Roland , Seidemann Lena , Dietrich Arne 
Published: January 2025

Abstract

Purpose
Obesity and type 2 diabetes (T2DM) are major risk factors for hepatic steatosis. Diet or bariatric surgery can reduce liver volume, fat content, and inflammation. However, little is known about their effects on liver function, as evaluated here using the LiMAx test.

Methods
In the MetaSurg study (RCT on the effects of different Roux-en-Y gastric bypass (RYGB) limb lengths on diabetes remission in patients with BMI ≥ 27 to ≤ 60 kg/m2 and T2DM; trial registration: DRKS00007810, German Clinical Trials Register Freiburg), 24 consecutive patients underwent liver function (LiMAx) and imaging assessments (MRI, transient elastography; TE) before and after diet and surgery. Two weeks before surgery, the patients received a hypocaloric protein-rich diet.

Results
Nine of 18 patients had a pathologic LiMAx value (≤ 315 µg/kg/h) at baseline. After two weeks of diet, LiMAx values improved (p = 0.01, paired t test, n = 15). LiMAx values further recovered six months after RYGB (p = 0.01, paired t test, n = 15), which was accompanied by decreased liver volumes (p = 0.005, paired t test, n = 10), proton density fat fraction (p = 0.003, paired t test, n = 12), and TE measurements (p = 0.032, paired t test, n = 14). The need for medical diabetes treatment decreased from 100 to 35%.

Conclusion
Liver function improved after a two-week hypocaloric protein-rich diet and metabolic surgery in patients with obesity and T2DM. These data suggest that a two-week diet for this group of patients prior to abdominal surgery could improve a presumably impaired liver function.
Morphological and histochemical characteristics of the foregut, midgut, and hindgut, and their alterations during ovarian development in female freshwater prawn, Macrobrachium rosenbergii
Authors: Vetkama Warinthip , Tinikul Ruchanok , Sobhon Prasert , Tinikul Yotsawan 
Published: January 2025

Abstract
The anatomical, histological, and histochemical characteristics of the foregut (FG), midgut (MG), and hindgut (HG), as well as their alterations during the ovarian cycle in female prawns, Macrobrachium rosenbergii, were investigated. The esophagus (ESO), cardia (CD), and pylorus (PY) are the main components of the FG. An epithelium (Ep) with thick cuticle (Cu) layers lining the ESO, and the ESO is encircled by the ESO glands. The CD has a thick musculature, whereas the Ep of the PY are characterized by numerous villi and columnar Ep cells with a thinner layer of Cu. The inner longitudinal (LM) and the outer circular (CM) muscles were both present in the PY. The MG is lined by Ep cells which are connected to the basement membrane, and it lacks Cu. Microvilli, and subapical vacuoles are visible on the apical surface of Ep cells of the MG. The outermost layer is characterized by a dense strip of elastic fibers and a cluster of collagen fibers. The HG has the Ep cells with a thin Cu layer, and the HG glands form a rosette-like structure. The HG is surrounded by the CM and the LM fibers. The reactivities of Periodic Acid Schiff and Alcian Blue in these digestive organs altered throughout the ovarian cycle, and this was supported by the increased expression of mucin levels as ovarian maturation progressed. Our results offer novel and significant insights into the anatomical and histochemical structures of these digestive organs, and demonstrate a significant correlation between ovarian development and feeding in the female prawn, M. rosenbergii.
Video-based robotic surgical action recognition and skills assessment on porcine models using deep learning
Authors: Hashemi Nasseh , Mose Matias , Østergaard Lasse R. , Bjerrum Flemming , Hashemi Mostaan , Svendsen Morten B. S. , Friis Mikkel L. , Tolsgaard Martin G. , Rasmussen Sten 
Published: January 2025

Abstract

Objectives
This study aimed to develop an automated skills assessment tool for surgical trainees using deep learning.

Background
Optimal surgical performance in robot-assisted surgery (RAS) is essential for ensuring good surgical outcomes. This requires effective training of new surgeons, which currently relies on supervision and skill assessment by experienced surgeons. Artificial Intelligence (AI) presents an opportunity to augment existing human-based assessments.

Methods
We used a network architecture consisting of a convolutional neural network combined with a long short-term memory (LSTM) layer to create two networks for the extraction and analysis of spatial and temporal features from video recordings of surgical procedures, facilitating action recognition and skill assessment.

Results
21 participants (16 novices and 5 experienced) performed 16 different intra-abdominal robot-assisted surgical procedures on porcine models. The action recognition network achieved an accuracy of 96.0% in identifying surgical actions. A GradCAM filter was used to enhance the model interpretability. The skill assessment network had an accuracy of 81.3% in classifying novices and experiences. Procedure plots were created to visualize the skill assessment.

Conclusion
Our study demonstrated that AI can be used to automate surgical action recognition and skill assessment. The use of a porcine model enables effective data collection at different levels of surgical performance, which is normally not available in the clinical setting. Future studies need to test how well AI developed within a porcine setting can be used to detect errors and provide feedback and actionable skills assessment in the clinical setting.
Digitale Begleitung der Therapie und Nachsorge beim Mammakarzinom
Authors: Würstlein Rachel , Wolff Josefine , Harbeck Nadia , Wülfing Pia 
Published: January 2025

Zusammenfassung
Aufgrund multimodaler therapeutischer Konzepte für Brustkrebspatientinnen mit Brustkrebs im Frühstadium führen Behandlungen bei mehr als 70–80 % der Fälle zu vollständiger Heilung. Die Belastungen können enorm sein. Brustkrebsüberlebende, aber auch Patientinnen mit metastasierender Erkrankung stehen vor einer Vielzahl physiologischer und psychosozialer Herausforderungen, oft im Umgang mit späten und langfristigen Folgen intensiver Therapien. Trotz dieser Schwierigkeiten vertreten Brustkrebspatient:innen einen starken Wunsch, die Gesundheit aktiv zu managen. Um dies zu ermöglichen, steht die Edukation und ein anschließendes Coaching für einen nachhaltigen Effekt an erster Stelle. Es gibt zahlreiche digitale Unterstützungsangebote für Patientinnen mit Brustkrebs, die jedoch große Unterschiede in Bezug auf die Qualität der Inhalte, der Nutzerfreundlichkeit und der Evidenz zur Wirksamkeit aufweisen. Neben Patient-Reported Outcomes, die mittlerweile international in zahlreichen Studien therapiebegleitend und auch während der Nachsorge genutzt wurden, um Nebenwirkungen frühzeitig zu erkennen und die Symptomkontrolle zu verbessern, spielt auch digitales und analoges Coaching eine immer wichtigere Rolle. Alle diese Möglichkeiten konnte bereits in randomisiert-kontrollierten Studien signifikante und klinisch relevante Ergebnisse zeigen. Das Potenzial digitaler Begleitungen und Coachings von Patientinnen mit Mammakarzinom können nicht nur die gesundheitsbezogene Lebensqualität, sondern auch die Adhärenz zur Therapie, das progressionsfreie Überleben und das Gesamtüberleben positiv beeinflussen.
Prevalence of vertebral fractures at death
Authors: Ogawa Noriko , Yamamoto Masahiro , Kobayashi Rie , Kawamura Atsuko , Matsumoto Akihiro , Otani Hiroki , Kanasaki Keizo 
Published: January 2025

Abstract

Introduction
Despite many studies on the prevalence of vertebral fractures (VFs), the VF prevalence at death in the Japanese population remains unclear.

Materials and methods
We evaluated the VF prevalence at death in a Japanese cohort using autopsy imaging computed tomography (AiCT). We enrolled 365 cadavers (188 men, 177 women, mean age of 84.6 years) donated for anatomical dissection at Shimane University School of Medicine. The VFs were diagnosed using the semiquantitative technique of Genant from the first cervical vertebra to the fifth lumbar vertebra.

Results
The overall VF prevalence was 69.6% (58.5%/81.4% in men/women), of which 46.0% (29.8%/63.3% in men/women) had thoracic VFs, and 58.1% (50.5%/66.1% in men/women) had lumbar VFs. The most frequent fracture site was lumbar spine 1 (L1) with 31.5% (22.9%/40.7% in men/women), followed by thoracic spine 12 (T12) with 31.0% (20.7%/41.8% in men/women). In terms of severity, 3.8% (4.8%/2.8% in men/women), 23.8% (27.1%/20.3% in men/women), and 41.9% (26.6%/58.2% in men/women) were Grades 1, 2, and 3. The VFs from T3 to L5 and of Grade 3 severity were significantly higher in women. VF and Grade 3 fractures were associated with a history of surgical intervention for femoral neck fractures. VFs were not associated with the following underlying causes of death: cancer, heart disease, senile death, cerebrovascular disease, pneumonia, and aspiration pneumonia.

Conclusion
The VF prevalence at death, assessed by AiCT in cadavers donated for anatomical dissection, was higher in both men and women compared with previous studies conducted on individuals aged ≥ 80 years in Japan.