bluuebunny/crossref_metadata_2025_split huggingface dataset:
Readmissions to a Nephrology Service in Abidjan: Prevalence and Risk Factors
Authors: Konan Serge Didier , Diopoh Sery Patrick Olivier , Ouattara Kolo Claude , Kouadio Marie Dominique , Yeo Donafologo Drissa , Yao Kouamé Hubert 
Published: July 2023

Abstract
Background : Readmission of patients with kidney disease is a reality in our practice setting.
Objectives : To assess the prevalence of readmission and identify factors associated with readmission and death of readmitted patients.
Materials and methods : This was a retrospective study conducted from the 1st of October 2017 to the 31st of December 2019 in the nephrology department of Treichville Teaching Hospital.
Results : During the study period, 1142 patients were admitted, of whom 154 patients were readmitted, representing a prevalence of 13.48%. The mean age of the patients was 42.31 [15 ;77 years] and the sex ratio was 1.35 in favour of men. The unemployed were the most represented (24.78%).
The average time between hospitalisations was 28.23 +/- 21.83 days [3; 123 days]. Patients were readmitted within 30 days of discharge in 65.48% of cases, between 30 and 60 days in 23.90% and after 60 days in 10.62%. Uremic syndrome was the main reason for readmission (68, 14%). The causes of readmission were dominated by dialysis failure (82.30%), followed by complications of vascular access, notably dialysis catheter infection (10.60%). Mortality was 30.97%. Obstructive nephropathy (p=0.029) and hypocalcaemia (p=0.030) were associated with the risk of hospital mortality. Severe anaemia was associated with early readmission (p=0.047) and hypertension with the risk of non-early readmission.
Conclusion : The prevalence of readmission at hospital is high. The causes are dominated by dialysis failure and dialysis catheter infection. Hence the interest in improving accessibility to dialysis for patients and raising awareness on prevention and management of risk factors of chronic kidney disease.
Synthesis, Characterization and Application of Potassium Incorporated Nitrogenous Nano Fertilizer
Authors: Sebastian Ardra , Devika P S , Nair Praseetha P , Devadas V S 
Published: July 2023

Abstract
Nano fertilizers have emerged as promising alternative smart fertilizers to ensure high crop production and soil restoration. In this study, we aimed to synthesize an eco-friendly and feasible potassium-incorporated nitrogenous nano fertilizer using physical and chemical methods. The synthesized nano fertilizers were characterized using Carbon, Hydrogen, Nitrogen and Sulphur (CH-NS) Elemental Analyzer, Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Scanning Electron Microscopy (SEM), and Dynamic Light Scattering (DLS) techniques. Based on the results, a suitable product was selected for preliminary trials in plant nutrition. The most essential nutrients for crops are macronutrients, such as nitrogen, phosphorus, and potassium. In the chemical synthesis, the nano fertilizer was prepared by extracting nutrients from ripe banana fruit rind (peels) and leaf extracts using chitosan nanoparticles, which served as a useful matrix for loading nutrients into crops. Subsequently, the synthesized nano fertilizer was analyzed, which revealed a particle size of 293 nm and a maximum nitrogen content of 3.51% and potassium content of 4.47%. For the physical synthesis, a planetary ball mill was used, where chitosan and potassium carbonate obtained from banana peel ash were ball milled to reduce their size. The results indicated a particle size of 5308 nm; a maximum nitrogen content of 5.55% and potassium content of 3.01%. After comparing both outcomes, the fertilizer synthesized using the chemical method was chosen for analyzing its effect on plant growth. Trials with crop plants demonstrated that the growth rates of plants increased with a decrease in the dosage of the nano fertilizer. Further elaborative field trials with different crops are suggested to evolve commercial recommendations to farmers.
High-resolution sequence stratigraphy from well-log patterns and base-level variations of the Paleocene - Early Eocene N’kapa Formation, Douala onshore Basin (SW Cameroon)
Authors: LEBOGO Serge Parfait KOAH NA , BISSO Dieudonné , ESSI Mike-Franck MIENLAM , MBESSE Cécile Olive 
Published: July 2023

Abstract
The present study aims to establish the stratigraphic architecture in order to understand the depositional history during the Paleocene- Early Eocene interval in the Douala Onshore Basin. The sequence stratigraphic analysis from gamma-ray logs and well cuttings was used to define stratigraphic surfaces and systems tracts based on the depositional sequence model. The results obtained show that the Paleocene-Early Eocene interval could be subdivided into three lithostratigraphic units (Unit 1, Unit 2, and Unit 3) of Middle Paleocene - Late Paleocene, Late Paleocene - Early Eocene, and Early Eocene age respectively. The sequence stratigraphic interpretation revealed three major stratigraphic surfaces : the sequence boundary (SB1) of the Middle Paleocene top, the transgressive surface (TS2) of the Late Paleocene, and the maximum flooding surface (MFS2) of the Early Eocene. The first highstand systems tracts (HST1) of the Middle Paleocene, the lowstand systems tract (LST2) of the Late Paleocene, the transgressive systems tract (TST2) of the Late Paleocene to Early Eocene, and the second highstand systems tracts (HST2) of the Early Eocene are the depositional sequences observed. The Paleocene-Eocene interval is therefore globally prograding, interrupted by a short transgressive episode of Late Paleocene to Early-Eocene age. Three cycles of base-level have been identified: the first cycle of base-level fall dated Middle Paleocene, the second cycle of rapid base-level rise which occurred between Late Paleocene to Early Eocene, and the third cycle of base-level fall dated Early Eocene. This observation confirms that the main factor which influenced the depositional history of Paleocene- Early Eocene succession in the Douala Onshore Basin was the eustatic sea-level changes due to the Cenozoic post-rift subsidence of the West African margin.
Docking, Synthesis and Evaluation of 4-hydroxy-1-phenyl-2(1H)-quinolone
Derivatives as Anticancer Agents
Authors: Tendulkar Chaitali Prabhu , Dessai Prachita Gauns , Mamle Desai Shivlingrao , Kadam Amrita 
Published: July 2023

Background:
The estimated number of cancer cases in India for the year 2022 was found to be 14,61,427. The development of chemotherapeutic agents has reduced the mortality rate, however,they have high toxicity which is a disadvantage. Many researchers have found out that quinolin-2-one possesses anticancer activity, with this background we thought of synthesizing the quinolin-2-one derivatives.

Objective:
This study aimed to carry out docking, synthesis, characterization, and evaluation of 2-(2-(4-Hydroxy-2-oxoquinolin-1(2H)-yl)phenyl/ substituted phenyl)-3-(phenylamino) thiazolidon-4-one derivatives (IVa-g) as an anticancer agent.

Method:
Diphenylamine and malonic acid treated with phosphoryl chloride gave compound I, which on formylation afforded compound II, which on reaction with various substituted aromatic phenylhydrazine derivatives gave compounds IIIa-g, which on further reaction with thioglycolic acid and anhydrous zinc chloride yielded the compounds IVa-g.

Result:
Among all the synthesized novel derivatives, compounds IV a-d showed 50% lysis in the IC50 range of 25-50µg for the A549 cell line, and compounds IVa, and IVb showed 50% lysis in the IC50 range of 25-50µg for the MDA-MB cell line. The compound, 3-((4-fluorophenyl)amino)-2-(2-(4-hydroxy-2-oxoquinolin-1(2H)-yl)phenyl)thiazolidin-4-one (IVg) was found to be the most active against both the cell line, A549 and MDA-MB with IC50 value of 0.0298µmol and 0.0338µmol respectively. The docking results revealed that the synthesized compounds exhibited well-conserved hydrogen bonding with one or more amino acid residues in the active pocket of EGFR tyrosine kinase domain with 4-anilinoquinazoline inhibitor erlotinib (PDB ID:1M17). Compound IVg showed the highest MolDock score of -137.813 compared to the standard drug Imatinib having a MolDock score of -119.354.

Conclusion:
Compound IVg showed the highest MolDock score and was also found to be most potent against both the cell line, A549, and MDA-MB.
PRODUKTIVITAS ALAT BERAT PADA GALIAN DAN TIMBUNAN
Authors: Nuzola Ma'ruf , Herni Mas , Kurniawan Septyanto 
Published: July 2023

Total pekerjaan alat berat adalah 14.118 m3 yang terdiri dari pekerjaan galian sebesar 13.020 dan pekerjaan timbunan sebesar 1.098. Untuk produktivitas Excavator SANY SY305 116,64 m3/ jam (menggali dan memuat kedalam Dumptruck), Excavator SANY SY365 233,29 m3/ jam (menggali dan memuat kedalam Dumptruck), Bulldozer D85ESS-2 369,40 m3/ jam (menggusur dan mendorong atau memindahkan tanah), Vibratorry Roller SAKAI SV515D 159,75 m3/ jam (menggilas dan memadatkan), Dumptruck kapasitas 24 dan 30 m3. 6,91 m3/ jam (galian 1), 14,85 m3/ jam (galian 2), 21,87 m3/ jam (timbunan). Analisa biaya sewa alat menggunakan satuan harga sewa yang ada dilokasi penlitian.
Untuk hasil perhitungan analisis lapangan didapat penggunaan biaya alat berat untuk pekerjaan galian dan timbunan membutuhkan waktu 100 jam, dengan biaya sewa alat berat sebesar 629.200.000. Dari hasil perhitungan alternatif 1 didapatkan alat berat membutuhkan waktu 95 jam dengan mengerjakan pekerjaan dengan volume yang ada dilapangan, dengan total biaya sewa alat berat sebesar 597.075.000, sedangkan dari hasil perhitungan alternatif 2 didapatkan waktu 204 jam dengan total biaya sewa sebesar 1.257.660.000. Untuk hasil tanah galian yang tidak terpakai akan diangkut ke lokasi pembuangan sedangkan tanah yang terpakai digunakan untuk timbunan dinding muka apron hulu.
Inclusion of physical medicine and rehabilitation in the medical curriculum: A step in the right direction
Authors: SINGH NEHA 
Published: July 2023

Background
Although physical medicine and rehabilitation (PMR) was first introduced in India in the 1960s, it was not until the 1990s when it was offered as an optional rotation to Indian medical graduates. Lately, with the introduction of a competency-based undergraduate curriculum in 2018, PMR has been included as an essential subject in the medical graduate curriculum, to be implemented from 2019. We aimed to ascertain the importance of incorporating PMR in the medical graduate curriculum while also discussing the awareness about PMR among Indian healthcare professionals.

Methods
We drafted an online questionnaire-based survey and sent that to participants through cloud-based software. Responses were collected over a period of 4 weeks and a descriptive analysis was performed.

Results
The initial hypothesis was that most healthcare professionals would be unaware of the scope of PMR as a medical specialty. The results of this study did not support our hypothesis with 96.8% of the participants being familiar with PMR as a medical specialty. In addition, 85% of the participants reported being introduced to PMR either in their medical school or during their residency training and 92% of the participants appreciated the late integration of PMR within the medical graduate curriculum.

Conclusions
Introduction of medical graduates to PMR would help in bridging the gaps faced by people with disabilities in accessing healthcare facilities. It would also help clinicians from other specialties to collaborate with physiatrists in a more coordinated manner.
EFFICACY OF INTRAVENOUS IMMUNOGLOBULINS IN RH INCOMPATIBLE NEONATES
Authors: MUHAMMAD IZHAR , HUSNA KHAN  , SANA PERVEZ  , TANVEER AHMAD  
Published: July 2023

BACKGROUND
This hemolytic disease of fetus and newborn is a condition in which there is immunologic hemolysis of fetal / neonatal red blood cells.
OBJECTIVE:
To compare the efficacy of intravenous immunoglobulins in reducing the need for exchange transfusion in Rh incompatible neonates.
MATERIALS AND METHOD:
This Randomized Controlled Trial was conducted from 1st September 2021 to 31st August 2022 at Department of Pediatric Medicine, Khyber Teaching Hospital, Peshawar. A total of 92 Rh incompatible neonates having bilirubin more than 8mg/dl were included in the study. Randomization was performed through lottery method. All neonates received conventional intensive phototherapy given by air shield and Ohmeda lamps with white light having an intensity of 22 μW/cm/nm plus blue light of 32 μW/cm/nm. Extra fluids (10 mL per kg) was administered during the phototherapy session. Subjects in group A received conventional intensive phototherapy and IVIG single dose(1 gm/kg). In group B saline was given instead of IVIG. A change in bilirubin of 1mg was considered effective after 4 hours of starting treatment. Data was recorded for efficacy.
RESULTS:
Mean age of Group A was 15.369± 4.98 days in Group A while 17.782± 3.31 days in Group B. Mean gestational age at birth was 37.608±1.58 weeks in Group A and 38.173±1.71 weeks in Group B. Mean parity was 3.534±0.28 in Group A and 3.387±0.36 in Group B. Mean hospital stay in group A was 3.2±1.5days while 5.7±1.2 days in group B. In group A, efficacy was seen in 38 (82.6%) patients as compare to 26 (56.5%) patients in group B, resulting in significant reduction of exchange transfusions, duration of phototherapy session and hospital stay (P=0.006).
CONCLUSION:
It is concluded that a IVIG administration in patients having significant hyperbilirubinemia of Rh incompatible neonates caused reduction in requirement for exchange transfusion ,decreased hospital and time duration of phototherapy treatment thus an effective and safe treatment
An ASIC Accelerator for QNN with Variable Precision and Tunable Energy-Efficiency
Authors: Wagle Ankit , Singh Gian , Khatri Sunil , Vrudhula Sarma 
Published: July 2023

<p>This paper presents TULIP, a new architecture for a variable precision Quantized Neural Network (QNN) inference. It is designed with the goal of maximizing energy efficiency per classification. TULIP is constructed by arranging a collection of unique processing elements (TULIP-PEs) in a single instruction multiple data (SIMD) fashion. Each TULIP-PE contains binary neurons that are interconnected using multiplexers. Each neuron also has a small dedicated local register connected to it. The binary neurons are implemented as standard cells and used for implementing threshold functions, i.e., an inner-product and thresholding operation on its binary inputs. The neurons can be reconfigured with a single change in the control signals to implement all the standard operations used in a QNN. </p>
<p><br></p>
<p>This paper presents novel algorithms for implementing the operations of a QNN on the TULIP-PEs in the form of a schedule of threshold functions. TULIP was implemented as an ASIC in TSMC 40nm- LP technology. A QNN accelerator that employs a conventional MAC-based arithmetic processor was also implemented in the same technology to provide a fair comparison. The results show that TULIP is 30-50X more energy-efficient than an equivalent design, without any penalty in performance, area, or accuracy. Furthermore, TULIP achieves these improvements without using traditional techniques such as voltage scaling or approximate computing. Finally, the paper also demonstrates how the run- time trade-off between accuracy and energy efficiency is done on the TULIP architecture.</p>
MCLA Task Offloading Framework for 5G-NR-V2X Based Heterogeneous VECNs
Authors: Mirza Muhammad Ayzed 
Published: July 2023

<p>Ensuring dependable quality of service (QoS) and quality of experience (QoE) for computation-intensive and delay-sensitive applications in vehicles can be a challenging task that impacts performance. While multi-access edge computing (MEC) based vehicular edge computing network (VECN) and vehicular cloudlets (VC) enable task offloading, but their prompt and optimal accessibility is another challenge. The conventional wireless technologies may not suffice to meet the stringent ultra-low latency and cost constraints of such applications. Nonetheless, the combination of different wireless technologies can enhance network performance and satisfy these requirements. Focusing on the computational efficacy of VECN, this paper proposes a mobility, contact, and computational load-aware (MCLA) task offloading scheme for heterogeneous VECN. The MCLA scheme dynamically considers the mobility, contact, and computational load of vehicles for making task offloading decisions. To optimize the performance, the MCLA scheme integrates the Mode-1 and Mode-2 of the 5G-NR-V2X standard, along with mmWave communications. The MCLA scheme provides an opportunistic switching mechanism between these modes and heterogeneous radio access technologies (RATs) to reduce communication delays and costs. Moreover, the MCLA scheme leverages public vehicles (i.e., public buses), in proximity by using their computational power to manage computational latency and cost. Furthermore, it also considers the shareable computations from passengers' mobile equipment within the public vehicle to improve the computation capacity of the public vehicles. Extensive evaluations and numerical results show that the proposed MCLA scheme significantly improves the task turnover ratio by 4%-15% with 4.7%-29.8% lower transmission and computation costs.</p>
PATHOGENETIC CLASSIFICATION OF CHOLANGITIS
Authors: Boyko V. V. , Smachilo R. M. , Maloshtan A. V. , Neklyudov A.A. , Klyosova M. O. , Chernyaev M. S. , Omelchenko V. F. , Volchenko O. V. , Kozlov D. S. 
Published: July 2023

Summary. Introduction. In the context of a wide variety of forms of acute and chronic cholangitis and a wide range of interventions, it is advisable to create a classification that facilitates the solution of tactical and strategic issues of treating patients with this serious disease.
Materials and methods. 200 patients with acute and chronic cholangitis were selected. There were 93 men, 107 women, the average age of the patients was (61.8±2.4) years.
Results of the study and their discussion. It is advisable to distinguish four groups of patients with acute and chronic cholangitis:
I group. The pathological process is localized only in the lumen of the main ducts. Surgical tactics of treatment of these patients is urgent endoscopic papilosphincterotomy (EPST) and clearence of the ductal system.
II group. The walls of the main bile ducts are involved in the pathological process, which led to their deformation and stricture. The vast majority of operations in this group are the reconstruction of the biliary tree.
III group. Patients with chronic recurrent cholangitis who have already undergone biliary reconstruction, but which did not prove to be effective or was complicated by various types of new strictures.
IV group. Patients with obstruction of the biliary tract caused by a cause localized outside the biliary system. In these patients, as a rule, the phenomena of cholangitis are mild, and the manifesting symptoms are biliary hypertension and liver failure.
Conclusions. The use of the proposed classification, based on the pathogenetic features of the development of cholangitis in various pathomorphological conditions, makes it possible to clearly define the issues of surgical tactics.
Predpovedanie vývoja cien stavebných prác a materiálov v stavebníctve na Slovensku a v zahraničí
Authors: Lederer Lukáš , Ellingerová Helena 
Published: July 2023

Príspevok sa zaoberá vývojom cenových indexov stavebných prác a materiálov v období od začiatku roku 2016 po koniec roku 2022, kedy trh bol a stále je veľmi nestabilný. Hodnota indexu cenového vývoja stavebných prác a materiálov v najnestabilnejšom období vzrástla o 35,2 percentuálneho bodu, za 15 mesiacov. Vzhľadom na takýto vývoj cien v stavebníctve, bolo a stále je takmer nemožné zo strany zhotoviteľov dodržať zmluvne dohodnuté ceny vo verejnom, ale aj v súkromnom sektore. Pri stavebných zákazkách na Slovensku a v zahraničí sú najpoužívanejšie typy zmluvných cien. Zmluva na základe jednotkových cien, kedy sa zhotoviteľ zaväzuje, že všetky podmienky splní za predpokladu úhrady skutočne vynaložených vlastných nákladov a primeraného zisku. Zmluva s pevne stanovenou cenou (paušálna cena) zaväzuje dodávateľa k vykonaniu prác a dodávok, bez ohľadu na jeho vlastné náklady vynaložené v súvislosti s dodávkou, špecifikovanou v zmluve. Je vôbec možné a účelné za týchto nekontrolovateľných podmienok prognózovať vývoj cien v stavebníctve? Aké predpovedné metódy by mohli byť pre tento účel efektívne?
Essencialidade de conteúdos de Matemática e suas relações com o trabalho na Educação Profissional e Tecnológica
Authors: Pontes Edel Alexandre Silva , De Oliveira Elinelson Gomes , Costa Clayton Pereira 
Published: July 2023

Este trabalho objetivou sugerir caminhos pedagógicos necessários para consolidar o processo de ensino e aprendizagem de Matemática no ensino técnico de nível médio integrado na Educação Profissional e Tecnológica (EPT) e suas relações com o trabalho. Metodologicamente, configura-se como um artigo de pesquisa qualitativa que emprega o procedimento de revisão bibliográfica. É importante compreender que a Matemática é indispensável para evolução da humanidade, para todo desenvolvimento tecnológico da era moderna, tendo suas suposições definidas por modelos usuais da natureza que especificam um padrão inquestionável na produção de conhecimento. O professor de Matemática da EPT precisa ampliar estratégias didáticas que possam envolver discentes na construção do pensamento matemático, tendo em conta toda a dinâmica e estado de espírito do aprendiz. Nota-se que o contexto do processo de ensino e aprendizagem de Matemática no ensino técnico de nível médio integrado na EPT é uma temática polêmica, já que, envolve diversas questões sobre práticas pedagógicas, muitas vezes resistentes a modelos tradicionais de aprendizagem, provocando incertezas no enfrentamento de novos modelos matemáticos.