bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bridging human resource management theory and practice: Implications for industry‐engaged academic research
Authors: Timming Andrew R. , Macneil Johanna 
Published: July 2023

AbstractThe link between academic theory and the professional practice of human resource management (HRM) is often tenuous and disjointed. The “gap” between theory and practice is damaging to academics and practitioners. On the one hand, academic research is often highly theoretical and methodologically complex. On the other, HR professionals tend to oversimplify advice on “how to solve” HRM “problems” and they may conduct research lacking rigor and nuance. Insofar as a bridge can be built between HRM theory and practice, significant benefits exist for both parties. Mick Marchington exemplified this bridge. His commitment to pluralism wrought significant influence on the professional practice of HRM through highly readable and practically useful theory. We look to Marchington's work to draw lessons on how we can better bridge theory and practice for the enrichment of academics and practitioners. We develop a framework contrasting “academic esotericism” with “practitioner reductionism.” We then propose a third way: “industry‐engaged academic research.”
Towards the diversification of lactococcal starter and non‐starter species in mesophilic dairy culture systems
Authors: Mahony Jennifer , Bottacini Francesca , van Sinderen Douwe 
Published: July 2023

AbstractLactococcus is one of the earliest identified fermentative bacterial genera and among its member species, the dairy‐associated Lactococcus lactis and Lactococcus cremoris are undoubtedly the best studied. These two species are believed to have evolved from plant‐associated lactococci and through genome decay and acquisition of plasmids, have adapted to the dairy niche. The past decade has witnessed a surge of activity in novel lactococcal species identification from insect, plant and animal sources. Currently, 22 Lactococcus species are described and in this review, we summarise the genome characteristics of and phylogenetic relationships among these species. Furthermore, we explore the role of mobile elements including plasmids and bacteriophages in the diversification of lactococcal species. The pace of identification of novel lactococcal species suggests that the number of lactococcal species is likely to continue to grow. With additional sequence data for the emerging species, it will be possible to perform pathogenicity/virulence risk evaluations and generate extensive insights into the niche adaptation strategies through which they have evolved.
Cleavage‐resistant RIPK1‐induced autoinflammatory syndrome—A report of three generations with periodic fever and clinical response to colchicine
Authors: Chougule Akshaya , Iyengar Vaishnavi V. , Gowri Vijaya , Taur Prasad , Madkaikar Manisha R. , Bodhanwala Minnie , Desai Mukesh M. 
Published: July 2023

AbstractThe clinical syndrome caused by cleavage‐resistant RIPK1 is known as CRIA (Cleavage‐resistant RIPK1‐induced autoinflammatory) syndrome. We present a family with three generations affected by CRIA syndrome. Our index patient (P1), a boy born of a non‐consanguineous marriage, developed recurrent episodes of fever after 5 months of age, with variable periodicity. His father (P2) and paternal grandmother also had periodic fever. At 23 months of age, P1 was diagnosed with renal biopsy‐proven steroid‐responsive nephrotic syndrome. His first visit to our center was at 2 years of age. At presentation, he had failure to thrive, microcytic hypochromic anemia, and elevated inflammatory markers and interleukin‐6 levels. Amyloid A protein was elevated, serum creatinine was normal, and proteinuria resolved after addition of steroids. Next‐generation sequencing showed heterozygous mutation (c.970G>A, p.Asp324His) in RIPK1. This mutation has been reported to cause CRIA syndrome. P2 and P1's asymptomatic younger brother had the same mutation. All the affected members showed variability with respect to frequency and duration of periodic fever as well as the age of onset. Both P1 and P2 had elevated amyloid A, with no evidence of renal dysfunction. P1 and P2 showed improvement in the intensity of fever spikes with colchicine treatment; however, both continue to have periodic fever.
Expression of calcitonin gene‐related peptide induces ligament degeneration through endochondral ossification in osteoarthritis
Authors: Tokumoto Maya , Nakasa Tomoyuki , Nekomoto Akinori , Ishikawa Masakazu , Ikuta Yasunari , Miyaki Shigeru , Adachi Nobuo 
Published: July 2023

AbstractAimOsteoarthritis (OA) is a disease in which degeneration occurs in various tissues such as cartilage and subchondral bone. Degeneration of ligaments also plays an important role in OA progression, resulting in an increase in chondrocytes and ossification, but the factor that causes this is still unclear. It is reported that the expression of calcitonin gene‐related peptide (CGRP) increases OA progression, and CGRP might play a role in ligament degeneration because CGRP has a function in endochondral ossification. The purpose of this study is to analyze the mechanism of ligament degeneration and the function of CGRP.MethodsTo examine the relationship between ligament degeneration and CGRP expression, human posterior cruciate ligaments (PCL) from OA patients, and senescence‐accelerated mouse prone 8 (SAMP8) mice were histologically analyzed. The effect of CGRP on human ligament cells on chondrogenesis, osteogenesis, and adipogenesis was also examined.ResultsIn human PCL and SAMP8 mice, CGRP expression increased as degeneration progressed, and decreased in severe degeneration. CGRP was expressed in the chondrocyte‐like cells with SOX9. CGRP‐positive cells expressing type II collagen increased with OA progression. CGRP upregulated the gene expression of VEGF, SOX9, RUNX2, COL10a1, and MMP13 in the human ligament cells. CGRP also promoted chondrogenesis and osteogenesis from the human ligament cells.ConclusionDuring OA progression, CGRP plays a role in the transdifferentiation from ligament cells to chondrocytes and promotes endochondral ossification in the ligament. CGRP would be the therapeutic target to prevent ligament degeneration.
Sublingual floor of Rahmani sheep (Ovis aries): A scanning electron microscopy and histomorphology analysis
Authors: Madkour Fatma A. , Mohamed Alsayed A. , Mohammed Elsayed S. I. , Choudhary Om Prakash 
Published: July 2023

AbstractThe current study investigated the sublingual floor of Rahmani sheep (Ovis aries). Samples from nine healthy adult sheep have been analysed using morphometrical, scanning electron microscopic (SEM), and histological examination. The sublingual floor of the sheep was formed of a rostral prefrenular part (spatula‐shaped) and two lateral sublingual recesses. Right and left sublingual caruncles were asymmetrical in length and each one had a serrated border, divided into three papillae. At higher magnifications, the three papillae of the sublingual caruncle's edge were variable in shape, with other two papillae were demonstrated underneath the caruncle. Each sublingual recess had a sublingual fold (plica sublingualis) extended from the level of frenulum linguae till the glossopalatine arch, bordered with caudolaterally directed papillae till the level of first lower molar cheek teeth. The sublingual salivary glands were mixed (seromucoid) type. The glandular lobule consisted of mucous acini and sporadic serous acini, as well as the presence of some mucous acini capped by acidophilic cells, serous demilunes. The mucous acinus was formed of pyramidal mucous cells with pale stained cytoplasm and basally located nuclei. Two ducts; major sublingual and submandibular ducts were observed within the submucosa of the sublingual caruncle. The sublingual ductal pseudostratified columnar epithelium was interspersed by more goblet cells than that of the submandibular duct. Collagen fibres around the glandular lobules, intralobular and interlobular excretory ducts as well as the connective core of the papillae were noticed. By SEM, two epithelium‐lined pits on the surface of the sublingual floor mucosa caudal to the central incisive teeth were termed orobasal organ. As the first study to give a comprehensive analysis of the sheeps' sublingual floor, this one serves as a baseline for future clinical studies.
Phenotype and genotype correlation of inherited epidermolysis bullosa in Indonesia
Authors: Arline Diana Inne , Tan Ene‐Choo , Gondokaryono Srie Prihianti , Koh Mark Jean‐Aan , Dwiyana Reiva Farah , Rahardja July Iriani , Yogya Yuri , Rafi'ee Khadijah , Suwarsa Oki 
Published: July 2023

AbstractBackgroundInherited epidermolysis bullosa (EB) is a group of genodermatoses with considerable clinical and genetic heterogeneity. Clinical diagnosis of the EB subtypes is frequently imprecise and requires confirmation with genetic testing. There is still limited study using genetic testing to identify EB subtypes in Indonesia. This study aims to identify the pathogenic variants of inherited EB patients at the Department of Dermatology and Venereology, Universitas Padjadjaran—Dr Hasan Sadikin General Hospital in Bandung, West Java, Indonesia and to describe the correlation between the phenotype and genotype of our patients.MethodsTwelve patients clinically diagnosed with EB were included in this study. Genetic testing was performed in collaboration with KK Women's and Children's Hospital, Singapore.ResultsPathogenic variants were identified in the COL7A1 gene in seven patients, namely Dominant Dystrophic EB (DDEB) with mutation types c.5945G>T, c.6218G>A, Recessive Dystrophic EB (RDEB) c.2005C>T, c.6081dup, c.1268C>T, c.1784C>T which are all known mutations. Novel mutations were found in the COL7A1 gene in two patients namely DDEB c.6253G>T and RDEB c.6740C>T. Two EB Simplex (EBS) patients showed mutation KRT14 gene as c.356T>C, c.373C>T which are known mutation. In addition, a novel mutation in LAMA3 gene c.2649del was found in one Junctional EB (JEB) patient.ConclusionThe molecular diagnoses of 12 Indonesian EB patients were identified, of which three were novel pathogenic variants. Concordance between the initial clinical diagnosis and genetic testing was only 33%. This demonstrated the importance of early genetic testing for accurate diagnosis, prognostication, management and genetic counselling.
Association of sleep duration and quality with serum testosterone concentrations among men and women: NHANES 2011–2016
Authors: Hernández‐Pérez Jesus Gibran , Taha Shaden , Torres‐Sánchez Luisa E. , Villasante‐Tezanos Alejandro , Milani Sadaf A. , Baillargeon Jacques , Canfield Steven , Lopez David S. 
Published: July 2023

AbstractBackgroundThe association between testosterone concentrations and sleep duration is poorly understood.ObjectiveTo evaluate the association between sleep duration and quality with serum testosterone concentrations and its variation by sex and age.MethodsData were analyzed for 8748 men and women (≥20 years old) who participated in the cycles of the National Health and Nutrition Examination Survey 2011–2016, a cross‐sectional study. Total testosterone (ng/dL) was measured and categorized (low, moderate, and high) based on established cut‐offs for men and its tertile distribution among women. Sleep duration was classified as ≤6, 7–8, and ≥9 h. Sleep quality was classified as poor or good based on the frequency of trouble falling or staying asleep or sleeping too much. Weighted multivariable adjusted and multinomial logistic regression models were conducted to assess these associations.ResultsThe association between sleep duration and testosterone concentrations, varied according to sex and age. Sleep deprivation (≤6 h) was associated with high testosterone (odds ratio = 3.62; 95% confidence interval: 1.37, 9.53) among young men (20–40 years old); meanwhile, middle‐aged men (41–64 years old) who reported more sleep duration had low testosterone (odds ratio = 2.03; 95% confidence interval: 1.10, 3.73). A J‐shaped association between sleep duration and low testosterone (odds ratio≤6 h = 1.57; 95% confidence interval: 1.10, 2.27; odds ratio≥9 h = 2.06; 95% confidence interval: 1.18, 3.59) was observed in women aged 41–64 years. We did not find any association with sleep quality.ConclusionThe association of sleep duration with serum testosterone concentrations varies with sex and age group. Prospective studies are warranted to confirm these sex and age group differences.
Mid‐term outcomes of minimally invasive infrapubic approach for inflatable penile prosthesis implantation: A single‐center study and literature review
Authors: Di Pierro Giovanni Battista , Di Lascio Giovanni , Lemma Andrea , Grande Pietro , Frisenda Marco , Del Giudice Francesco , Antonini Gabriele , Nardi Francesco , De Berardinis Ettore , Cristini Cristiano , Franco Giorgio , Sciarra Alessandro , Salciccia Stefano 
Published: July 2023

AbstractBackgroundThe minimally invasive infrapubic approach (MIIA) for inflatable penile prosthesis (IPP) placement has shown favorable peri‐operative safety and efficacy profile, but scarce data exist on long‐term follow‐up.ObjectivesWe investigated the safety and efficacy of IPP implantation via the MIIA after a minimum 5‐year follow‐up.Materials and methodsWe identified data of implanted patients prospectively included in our institutional database. Complications and functional outcomes were assessed by using validated tools. Specifically, quality of life and patient satisfaction were evaluated by the Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) questionnaire. Kaplan–Meier method was used to analyze IPP survival (defined as a working IPP).ResultsOverall, 67 patients implanted by MIIA with a median (IQR) age of 64 years (61−70) were included. The median (IQR) follow‐up duration was 71 months (63−80). Fifteen (22%) patients experienced complications: minor (Clavien ≤2) events included changes in penile sensitivity (n = 1; 1.5%), orgasmic dysfunction (n = 1; 1.5%), pain (n = 5; 7%), urinary tract infection (n = 2; 3%), and chronic discomfort (n = 1; 1.5%); major (Clavien 3) complications were represented by mechanical failure (n = 3; 4.5%), IPP infection (n = 1; 1.5%), and cylinder protrusion (n = 1; 1.5%). The estimated IPP survival was 94% (95% CI, 91.4−96.6), 92.5% (95% CI, 89.7−95.3), and 92.5% (95% CI, 89.7−95.3) at 3, 5, and 7 years after implantation, respectively. In patients using the device at follow‐up (n = 61; 91%), median (IQR) scores for QoLSPP domains demonstrated favorable functional outcomes and patient satisfaction: functional 21 (19−23), personal 16 (15−18), relational 14 (12−15), and social 12 (11−14).Discussion and conclusionThis study represents the longest follow‐up using validated tools to assess the outcomes of IPP implantation via MIIA so far. IPP placement via MIIA confirms to be safe and to offer high satisfaction to both patients and partners at mid‐term evaluation.
Locating a shadowy state in queer, feminist politics
Authors: Majumder Atreyee 
Published: July 2023

SummaryIn this commentary, part of a book forum on Srila Roy's (2022) book Changing the Subject: Feminist and Queer Politics in Neoliberal India, I argue that the feminist and queer movement, in response to the neoliberal turn in India, is not totally separate from the Indian state formations. In fact, a shadowy state emerges in the affective life of citizens as an expression of what Timothy Mitchell would have called “state effect.”
Editorial: Will MRI‐PDFF become the new standard for steatosis assessment in NAFLD?
Authors: Pappa Angeliki , Wenzl Tobias 
Published: July 2023

LINKED CONTENTThis article is linked to Kim et al papers. To view these articles, visit https://doi.org/10.1111/apt.17564 and https://doi.org/10.1111/apt.17619
Editorial: Pip pip to PIPs (post‐ inflammatory polyps) as a neoplasia risk factor in IBD? Authors' reply
Authors: Kirchgesner Julien , Beaugerie Laurent 
Published: July 2023

LINKED CONTENTThis article is linked to Wolf et al papers. To view these articles, visit https://doi.org/10.1111/apt.17495 and https://doi.org/10.1111/apt.17565
Editorial: Let your muscles do the talking—what can muscle quality tell us about hepatic fibrosis?
Authors: Petroff David , Wiegand Johannes , Karlas Thomas 
Published: July 2023

LINKED CONTENTThis article is linked to Lee et al papers. To view these articles, visit https://doi.org/10.1111/apt.17601 and https://doi.org/10.1111/apt.17627
Editorial: Will MRI‐PDFF become the new standard for steatosis assessment in NAFLD? Authors' reply
Authors: Huang Daniel Q. , Loomba Rohit 
Published: July 2023

LINKED CONTENTThis article is linked to Kim et al papers. To view these articles, visit https://doi.org/10.1111/apt.17564 and https://doi.org/10.1111/apt.17606
Editorial: MTTP, hepatic steatosis, and plasma lipids—still more questions than answers. Authors' reply
Authors: Hehl Leonida , Schneider Carolin Victoria , Rader Daniel J. 
Published: July 2023

LINKED CONTENTThis article is linked to Schneider et al papers. To view these articles, visit https://doi.org/10.1111/apt.17566 and https://doi.org/10.1111/apt.17611
Editorial: Let your muscles do the talking—what can muscle quality tell us about hepatic fibrosis? Authors' reply
Authors: Lee Yun Kyu , Koo Bo Kyung , Kim Won 
Published: July 2023

LINKED CONTENTThis article is linked to Lee et al papers. To view these articles, visit https://doi.org/10.1111/apt.17601 and https://doi.org/10.1111/apt.17618
Effects of single nucleotide polymorphisms of the folylpolyglutamate synthase gene on pemetrexed administration‐induced nephropathy
Authors: Mitarai Yuki , Tanino Ryosuke , Nakashima Kazuhisa , Hotta Takamasa , Isobe Takeshi , Tsubata Yukari 
Published: July 2023

AbstractAimsLong‐term administration of pemetrexed (PEM) in patients with lung cancer can cause renal damage, leading to treatment discontinuation. Previous reports have suggested that specific single nucleotide polymorphisms (SNPs) in the folylpolyglutamate synthase (FPGS) gene affect therapeutic efficacy; however, whether the FPGS SNPs affect renal function is unclear. Identifying SNPs related to renal damage during PEM administration may help predict the decrease in renal function caused by PEM.MethodsWe retrospectively examined age, sex, body weight, total administered PEM, combined platinum, estimated glomerular filtration rate (eGFR) and serum creatinine (SCr) levels before and after PEM administration in patients with non‐small cell lung cancer and searched for the alleles of FPGS SNPs (rs1544105 and rs10106) using DNA extracted from whole blood samples of patients.ResultsRenal function decreased after PEM administration in 26 cases overall. The SCr and eGFR indices showed decreased renal function irrespective of concomitant cisplatin use. Based on promoter activity and miRNA binding predictions, rs1544105‐C and rs10106‐T were hypothesized to increase FPGS expression. Single SNP analyses showed no significant differences in renal function between groups with and without each SNP. Multiple regression analysis revealed that the most significant factors for decreased renal function were sex on SCr and the number of SNPs on eGFR. In subgroup analyses, the patients with rs10106‐T showed a decline in renal function in the older group.ConclusionsThe number of FPGS SNPs may contribute to PEM‐induced renal impairment. Detecting FPGS SNPs may help predict PEM‐induced renal damage.
Attentional asymmetries in peripheral vision
Authors: Klatt Stefanie , Noël Benjamin , Schrödter Robin 
Published: July 2023

AbstractPrevious research on the use of peripheral vision to identify two spatially separated stimuli simultaneously has led to the conclusion that the focus of attention has the form of a symmetric ellipse with a broader expansion along the horizontal compared to the vertical meridian. However, research on pseudoneglect has indicated that attention is not symmetrically distributed to the whole visual field. Here, we test if the attention window is indeed symmetrical with regard to its shape and resolution during peripheral vision. The results indicate that the position of those stimuli relative to the focus of attention influences the ability to identify a given set of stimuli. Specifically, stimuli presented to the left and top of the fixation point were more frequently identified correctly compared to those presented to the right bottom. That is, the attention window is rather not symmetric, which must be considered in future studies on the nature of the focus of attention.
CIA‐II is associated with lower‐grade glioma survival and cell proliferation
Authors: Xiao Feng , Zhu Hong , Guo Yun , Zhang Zhe , Sun Gufeng , Xiao Yao , Hu Guowen , Huang Kai , Guo Hua 
Published: July 2023

AbstractBackgroundThe role of CIA‐II has been clarified in several types of tumors; however, whether dysregulated CIA‐II expression is also involved in the pathophysiology of lower‐grade glioma (LGG) remains undisclosed.MethodsA comprehensive pan‐cancer analysis of the expression patterns and prognostic significance of CIA‐II in miscellaneous tumors was undertaken. Subsequently, a detailed bioinformatics analysis was executed to identify putative correlations between CIA‐II expression and clinical features, prognosis, biological functions, immunological characteristics, genomic alterations, and chemotherapeutics in LGG. In vitro studies were implemented to examine the potential roles of CIA‐II in LGG.ResultsCIA‐II expression was found to be abnormally elevated in a variety of tumors, including LGG. Additionally, patients with LGG with higher CIA‐II expression owned worse prognosis. Importantly, the results declared that CIA‐II expression was an independent prognostic indicator for LGG. Moreover, the expression of CIA‐II was tightly interrelated with immune cell infiltration, gene mutations, and chemotherapeutics in LGG. In vitro studies revealed that CIA‐II was increased and strongly related to the cell proliferation in LGG.ConclusionCIA‐II may be an independent prognostic factor and a serviceable therapeutic target in LGG.
Levodopa improved different motor symptoms in patients with Parkinson's disease by reducing the functional connectivity of specific thalamic subregions
Authors: Liu Wan , Shen Yang , Zhong Yuan , Sun Yu , Yang Jiaying , Zhang Wenbin , Yan Lei , Liu Weiguo , Yu Miao 
Published: July 2023

AbstractBackgroundThe thalamus is an important relay station for the motor circuit of human. Levodopa can reverse the clinical manifestations by modulating the function of motor circuits, but its detailed mechanisms are still not fully understood. We aimed to explore (1) the mechanism by which levodopa modulates the functional connectivity (FC) in the subregions of the thalamus; (2) the relationship between the changed FC and the improvement of motor symptoms in Parkinson's disease (PD) patients.MethodsResting‐state functional MRI was used to scan 36 PD patients and 37 healthy controls. The FC between the subregions in the thalamus and the whole brain was measured and compared under different medication states of PD patients. The correlation between the improvement of motor symptoms and changes in FC in the thalamus subregions was examined.ResultsThe PD on state exhibited decreased FC between the right pre‐motor thalamus and the right postcentral gyrus, as well as the right lateral pre‐frontal thalamus and the right postcentral gyrus. These decreases were positively correlated with the improvement of resting tremor. The PD on state also exhibited decreased FC between the left lateral pre‐frontal thalamus and right paracentral lobule, which was positively correlated with the improvement of bradykinesia.ConclusionsThis study demonstrates that levodopa treats PD by decreasing the FC between the thalamus subregions and pre/post‐central cortex. Our results provide a basis for further exploration of the functional activity of thalamic subregions and offer new insights into the precision treatment in PD patients