bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adverb-adjective combinations in young writers’ English (EL1 and EL2)
Authors: Hasselgård Hilde 
Published: January 2023

The topic of the present study is adverb-adjective combinations in narrative writing by lower secondary school pupils in Norway and the UK. The investigation is based on subsets of the TRAWL (Tracking Written Learner Language) and GiG (Growth in Grammar) corpora and thus compares English as a second language with first-language usage (EL2 and EL1). A number of differences were identified between the two writer groups. While adverb-adjective constructions, such as so happy, much better and really bad, were more frequent and widespread in EL2, they showed more variability in EL1 regarding syntax, semantics and lexical choice. In particular, the amplifying function of modifiers was more dominant in EL2 writing at the cost of other modifier functions. There was also a stronger concentration on a few highly frequent intensifiers in the EL2 than in the EL1 material.
Causal Relationship Among SME’s Import, Export, Deposits, and Small Manufacturing Contribution to GDP – Toda Yamamoto Analysis
Authors: Muhammad Ahmad Mazher 
Published: January 2023

Purpose: The purpose of the study was to identify the causal relationship between Pakistani SMEs' imports, exports, domestic deposits, and GDP in the small manufacturing sector over 2007-Q1 to 2020-Q4.
Design/Methodology/Approach: Granger causality is a revolutionary and cutting-edge econometric technique that was presented by Toda and Yamamoto (1995). This technique enabled us to identify various kinds of observations, all of which are discussed in detail in the concluding part of the article.
Findings: Four-causal relationship among the variables which revealed the empirical results. (i) fluctuations in exports values, total imports values and deposit in domestic currency may cause the changes in GDP of small manufacturing sector in Pakistan (ii) fluctuations in GDP of small manufacturing and deposits in domestic currency may cause the changes in total exports value in SME sector in Pakistan while changes in total imports value do not make the cause of changes in total exports value in Pakistan SME sector (iii) fluctuations in GDP of small manufacturing and total exports value may cause the changes in total imports value in SME sector in Pakistan while changes in deposit in domestic currency do not make the cause of changes in total imports value in SME sector in Pakistan and (iv) fluctuations in GDP of small manufacturing, total exports value, and total import values does not make the cause of changes in deposit in domestic currency in SME sector in Pakistan.
Implications/Originality/Value: Using secondary data and an estimation method to take into account new factors, the study also makes a big contribution to the ongoing research on SMEs in Pakistan.
Vía JAK-STAT e inhibidores JAK
Authors: Minaudo Carla 
Published: January 2023

La vía JAK-STAT (Janus Kinasas) es una cadena de traducción de señales intracelulares, que se activa a través de receptores de citoquinas I y II.
Mediante esta vía, varias moléculas de importancia en dermatología ejercen sus efectos: IL2, IL4, IL7, IL5, IL6, IL9, IL12, IL13, IL15, IL21, IL23, INFa e INFb, entre otras. También es la señal intracelular de hormonas como la prolactina y la hormona de crecimiento.
La inhibición de distintos componentes de esta vía es utilizada como terapéutica en enfermedades reumatológicas y un número cada vez mayor de patologías cutáneas.
Los inhibidores JAK surgieron en la práctica médica hace aproximadamente 11 años, con el ruxolitinib y poco tiempo después el tofacitinib. En la actualidad, se dispone de varias moléculas aprobadas y muchas otras en etapa experimental.
En este artículo se desarrollarán la organización intracelular y las funciones de la vía JAK-STAT con sus variantes principales relacionadas a enfermedades inmunomediadas, así como las características más relevantes de los inhibidores JAK.
Reacciones cutáneas asociadas al tratamiento de las queratosis actínicas con 5-fluorouracilo
Authors: Pastore Federico 
Published: January 2023

El tratamiento de las queratosis actínicas con 5-fluorouracilo (5-FU) al 5% genera reacciones cutáneas de diferente intensidad.
Se empleó 5-FU tópico 2 veces por día durante 4 semanas para el tratamiento de las queratosis actínicas.
Los pacientes puntuaron la presencia de reacciones cutáneas desde ausentes, leves-moderadas y severas.
Tratamiento con talidomida del eritema multiforme crónico
Authors: Pastore Federico 
Published: January 2023

El eritema multiforme puede evolucionar a una forma recurrente o persistente. El valaciclovir es el tratamiento de primera línea en estos casos. No hay consenso en cuanto a la elección de una segunda línea de tratamiento cuando este falla.
Se evaluó la eficacia de la talidomida para el tratamiento del eritema multiforme crónico (recurrente y persistente) en pacientes adultos que habían tenido al menos un fracaso terapéutico con algún tratamiento previo a la utilización de este fármaco.
Después de 6 meses de tratamiento con talidomida, el 66% de los pacientes estaban en remisión total, el 14% habían interrumpido el tratamiento y el 7% habían experimentado al menos un brote.
La dosis media utilizada fue de 50 mg/día.
Expanding the Universe of Education
Authors: Parsons Elizabeth 
Published: January 2023

We understand education to mean the encouragement as well as the delivery of the means to help people to inform themselves of the significance of the world beyond their normal communities and outside the bounds of their families and personal experience. We understand rural to mean any environment which can result in forms of isolation, caused by economic, geographic, physical or social factors, which inhibit people from realising their full personal enjoyment and their potential as contributing members of the Australian society. The three major tasks in expanding the universe of education for rural people in Australia therefore involve:
educating rural people to their needs in a rapidly changing economic, political and social environment;
educating rural people on the irreversible and unavoidable changes which will transmogrify the demography and economy of Australia within their lifetimes;
educating rural people on the range of facilities, support services and technologies which they can use to enhance their cultural, economic, personal and social well being.
Assessing the validity of admission test into the internship programme at a private university in Pakistan
Authors: Qamar Riaz  , Yousuf Naveed , Shamim Muhammad Shahzad 
Published: January 2023

Objective: To report the development and validity assessment of a comprehensive model of assessment method comprising written test and multiple mini interviews for selection in a medical internship programme.
Method: The psychometric validation study was conducted at the Aga Khan University, Karachi, and comprised anonymised scores of written admission test, multiple mini interviews and exit written exams for all the interns who completed their internships in 2018 and 2019. Correlation between admission and exit tests, and predictions were assessed. Data was analysed using SPSS 20.
Results: There were 160 interns; 80(50%) each in 2018 and 2019. Mean scores were 68.8+4.40% for written tests and 76.7+4.66% for multiple mini interviews. The mean score for exit examination was 68.1+6.84%. The Cronbach’s alpha of scores on the written admission test was 0.82 and 0.88 for the two years, respectively, while for the multiple mini interviews, the corresponding values were 0.81 and 0.94. The written admission and exit tests were moderately correlated (0.44) while the correlations of multiple mini interviews scores with written admissions and exit tests were -0.28 and 0.04, respectively.
Conclusion: The selection process should comprise multiple measures of assessment to ensure the selection of the best candidates.
Key Words: Multiple mini interviews, Predictive validity, Admission test.
Analisis Faktor Internal terhadap ROA dengan CAR sebagai Intervening pada Perbankan yang Tedaftar di BEI Tahun 2018- 2020
Authors: Fadhilah Nur , Hermuningsih  Sri , Wiyono Gendro 
Published: January 2023

The purpose based on this research is to analyze the internal factors of NPL (Non-Performing Loan), LDR (Loan to Deposit Ratio) to ROA (Return on Assets) using CAR (Capital Adequacy Ratio) in intervening and in this research sample using the banking sector contained in the Stock Exchange. The Indonesian Stock Exchange (IDX) from 2018 to 2020 uses 45 banks. By using purposive sampling technique, based on this research, there are still 32 companies. The quantitative data method is attached to the financial statements for that year. In this research sample, the banking sector on the Indonesia Stock Exchange (IDX) from 2018 to 2020 uses 45 banks. By using purposive sampling technique, based on this research, there are still 32 companies. The quantitative data method is attached to the financial statements for that year. So that this research results: (1) LDR has no effect on CAR, (2) NPL has no effect on CAR. (3) LDR has no effect on ROA, (4) NPL has a positive and significant effect on ROA, (5) CAR has no effect on ROA.
Keywords: NPL (Non Performing Loan), LDR (Loan to Deposit Ratio), ROA (Return on Assets)
Afghanistan and United States foregin relation after September 11th 2001
Authors: Khurami Hafiza 
Published: January 2023

The incident of 11 September 2001 played an important role the relations between Afghanistan and the United States. After that Afghanistan was the axis of attention to US foreign policy. The US Military presence in Afghanistan has different reason. Afghanistan is a tool for the United States to achieve its goal, because Afghanistan has a special geopolitical position through which it can achieve its ideological goals, one of these reasons could be the struggle against Islam.
because the Middle East countries are the cradle of Islam. And the United States considers these countries to be the source of terrorism, which is the enemy of the United States. And to achieve its political goals by establishing military bases in Afghanistan under the influence of powers such as Russia, China and Iran. Afghanistan's proximity to the Middle East and Central Asia, which are rich in oil and gas resources, is also economically important to the United States. So Afghanistan's geopolitical position could be a good platform to achieve these US goals.
EFEITOS DA SUPLEMENTAÇÃO DE PROBIÓTICOS DOS GÊNEROS LACTOBACILLUS E BIFIDOBACTERIUM NOS PERFIS LIPÍDICO E GLICÊMICO DE GESTANTES
Authors: Mesquita de Godoy Carla , Pereira Barbosa Jéssica , De Morais Carla 
Published: January 2023

Durante a gestação observam-se algumas alterações no metabolismo materno com vistas a garantir o suporte nutricional e adequado crescimento e desenvolvimento fetal. Estudos recentes observaram uma relação da microbiota intestinal com as alterações do período gestacional e sugerem uma abordagem terapêutica com uso de probióticos para redução da resistência à insulina e melhora do perfil lipídico, inclusive como prevenção do DMG. O objetivo deste trabalho foi avaliar os efeitos da suplementação de probióticos no metabolismo materno, verificando o potencial dos gêneros Lactobacillus e Bifidobacterium em regular marcadores do perfil glicêmico e lipídico de gestantes. Para isso, foram realizadas buscas nas bases de dados PubMed e Scielo, seguindo critérios específicos de busca. Foram analisados 11 ensaios clínicos, realizados em mulheres grávidas com alguma alteração metabólica gestacional mediante à intervenção suplementar de micro-organismos probióticos e com média de duração de intervenção de 6 a 8 semanas, encontrando desfechos positivos em 82% dos estudos. A suplementação de probióticos em gestantes com DMG no 2º e 3º trimestres gestacional por um período mínimo de 6 semanas, teve efeitos benéficos na expressão de genes relacionados à insulina e inflamação, controle glicêmico, poucos perfis lipídicos, marcadores inflamatórios e estresse oxidativo. A suplementação de probióticos pode ser um relevante agente terapêutico para pacientes com DMG, mas que avançar em mais estudos com gestantes, de preferência as saudáveis, para avaliar a diferença nos marcadores do perfil lipídico e glicêmico se faz necessário para ampliar as informações e fazer comparações mais aprofundadas.
Interventions results treatment of chronic total occlusion of the femoral artery at Cardiovascular Center – E hospital
Authors: Ngoc Ly Duc , Hung Pham Manh , Nguyen Phan Thao , Thuy Nguyen Tran , Huy Nguyen The 
Published: January 2023

Objectives
Evaluation of early and medium-term results of percutaneous interventional procedure to treat CTO femoral artery occlusion at Cardiovascular Center of Hospital E and some factors affecting the intervention results of this procedure
Methods
Descriptive, prospective, non-control study, from July 2021 to July 2022, had 38 patients diagnosed with CTO femoral artery POBA and/or stenting
Result
The success rate of interventional technique for CTO of the superficial femoral artery is 94.7%. The rate of complications is 5.3%, 2 cases bleeding at the puncture site.
1. The rate of limb preservation or only minimal amputation was 97.4%. After 6 months, there were 10 cases (27.8%) of stent re-occlusion and had to be hospitalized for stent re- intervention.
2. Smoking has the highest rate in the study group, over 2/3 of the total number of patients, followed by hypertension and diabetes. Patients with stents length > 16cm had an increased risk of restenosis compared with stent length <16cm, (p=0.016). Retrograde intervention had a higher risk of stent occlusion at 6 months compared with antergrade intervention (p=0.012).
Conclusion
Intervention CTO femoral artery by percutaneous intervention has a high success rate, improving limb function and increasing quality of life, it is necessary to advise patients to give up smoking, take medication after the intervention. Consider placing multiple stents and too long stent. It is necessary to use Rotablator or IVUS limb vessels to optimize the outcome.
The role of limb-leads criterion in diagnosing the mechanism of wide QRS tachycardias
Authors: Dong Trinh Thi , Linh Pham Tran , Long Vien Hoang , Kien Hoang Trung , Thinh Do Duc , Thuy Nguyen Tran 
Published: January 2023

Background: The limb-lead criterion is a simple new standard with high diagnostic value to distinguish the cause of wide QRS tachycardia, easy to apply in emergency conditions.
Methods: A cross-sectional descriptive study of 61 patients with electrocardiogram of wide QRS tachycardia at Cardiovascular Center- Hospital E and Vietnam Heart Institute- Bach Mai Hospital from January 2017 to October -2022. Evaluating the value of limb – leads Criterionand comparing to several other criteria.
Results: In 61 patients, 43 patients with VT, 18 patients with SVT, 54.1% male, history of ischemic heart disease (3.3%), heart failure (11.5%), no history structural cardiovascular disease (83.6%). Mean heart rate was 182, 80 ± 20.58 bpm, average QRS width was 137.89 ± 12.59mms. Sensitivity, specificity, positive predictive value, negative predictive value of Brugada criterionwere 97.7%, 88.9%, 95.5%, 94.1%, respectively; of Pava criterionwere 53.5%, 88.9%, 92%, 44.4%; of Vereckei criterionwere 60.5%, 100%, 100%, 51.4%; of limb-leads criterion is 86.1%, 83.3%, 92.5%, 71.4%; when combining Limb lead and Pava criteriawere 90.9%, 82.4%, 93%, 77.8%.
Conclusion: The limb-lead criterion is an easy-to-usealgorithm, only using morphology to distinguish wide QRS tachycardias, has high diagnostic value, so it should widely applied in cardiovascular emergency.
Clinical case of medical treatment of chronic coronary syndrome at E Hospital
Authors: Nguyen Phan Thao , Thuy Nguyen Tran , Thanh Pham Duy , Cuc Nguyen Thi Thu , Ngoc Ly Duc , Anh Do Le , Giam Tran Minh , Lan Pham Thi Kim 
Published: January 2023

Coronary artery disease is a leading cause of death and disability in developing and developed countries. In Vietnam, coronary artery disease has also become one of the leading causes of death.
Chronic coronary syndrome is a disease related to the relative stability of coronary atherosclerotic plaque, in the absence of sudden rupture or after the acute phase or after intervention/surgery. As plaque progresses, causing significant narrowing of the coronary lumen (usually stenosis greater than 70% of the lumen diameter), symptoms may be present, most notably angina/dyspnea on exertion. and help when resting. Medical treatment of chronic coronary syndrome is an important issue. Two patients diagnosed as chronic coronary syndrome in 2015 received medical treatment after 5 years of coronary angiography from 80% of the left anterior descending and 60% of the left anterior descending with mild atherosclerosis. coronary artery disease in both patients.
Quality of life in patients after endoscopic surgery of mitral valve repair at Cardiovascular Center, E hospital
Authors: Trang Nguyen Thi Huong , Binh Nguyen The , Thuy Nguyen Tran 
Published: January 2023

Background: Endoscopic mitral valve repair is a new technique, bringing many benefits to patients. The assessment of the quality of life in patients after mitral valve repair is partly reflected as a result of this technique.
Methods: From 01/08/2022 to 31/12/2022, 106 patients after mitral valve repair who was eligible for the selection criteria were included in the study to assess the quality of life using the SF -36 score.
Results: 106 patients with a mean age of 55.4 years, of which mainly men accounted for 63.2% and average BMI was 23.3 kg/m2. The average follow-up time after 6.9 months showed that the patient could completely return to work after 3.7 months. Overall quality of life characteristics were good with 88.9 points. In which the physical health scores are mostly over 90 points, and the mental health scores are mainly above 80 points. BMI > 25kg/m2, marital status and NYHA classifications are related to quality of life after endoscopic mitral valve repair, with statistical significance with p<0.05.
Conclusion: The quality of life of patients after endoscopic mitral valve repair was good. Several factors were associated with quality of life such as BMI>25kg/m2, marital status and NYHA classifications.
Metafizyka dziś
Authors: Sobota Daniel Roland 
Published: January 2023

Wedle wielu potwierdzających się nawzajem diagnoz, które zaczęły pojawiać się od drugiej połowy XX wieku, żyjemy obecnie w „społeczeństwie spektaklu”. To spektakl wyznacza bowiem dominujący model życia społecznego. Rozwój mediów cyfrowych dokonał daleko idącej radykalizacji tej sytuacji, nie zmieniając zasadniczo jej prawdy: wirtualizacja wszechobecnego spektaklu potęguje jego ogólną omnipotencję.
Ta autocharakterystyka najnowszej epoki w dziejach świata przywołuje, ale też radykalizuje znaną skądinąd metaforę theatrum mundi. Pytanie zasadnicze artykułu brzmi następująco: jeśli rzeczywistość jest teatrem, to znaczy grą i nieprawdą, czy i jak możliwa jest dziś jeszcze metafizyka, która z założenia ma być domeną prawdy? Zwrot „metafizyka dziś” można rozumieć wszak wielorako. Jednym z jego znaczeń jest metafizyka tego, co daje (się) widzieć, to znaczy metafizyka dnia. Byłaby ona metafizyką zjawiania się i pokazywania, metafizyką fenomenalności, słowem – metafizyką fenomenologiczną. Powodem wyróżnienia przez autora podejścia fenomenologicznego jest, po pierwsze, to, że głównym tematem fenomenologii jest jawienie się i pokazywanie tego, co się jawi, a po drugie, coraz częściej powtarzane przekonanie, że to jawienie się należy badać nie czysto „teoretycznie”, lecz poprzez pełne uważności i zaangażowania, konkretne działanie, które uniemożliwia poznającemu zajmowanie li tylko biernej pozycji widza (jak było dotychczas). Poznawanie to sprawa czynienia. Dlatego to właśnie fenomenologia, rozumiana tutaj jako specyficzne działanie performatywne, wydaje się według autora najlepiej przygotowana do podjęcia metafizycznego wyzwania rzuconego przez spektakularną naturę współczesnej rzeczywistości.
Metafizyczny potencjał feminizmu - różnica płciowa i pytania o naturę świata
Authors: Jakubowicz-Prokop Zofia 
Published: January 2023

Artykuł jest poświęcony relacji teorii feministycznej z metafizyką, która według tezy autorki wyraża się między innymi w pojęciu różnicy płciowej. Przywołana zostaje krótka historia pojęcia i ukazane pojawiające się w ramach feministycznego dyskursu problemy z jego przyjęciem oraz towarzyszące mu zarzuty, które zostają sproblematyzowane przez odniesienie do filozofii Luce Irigaray. Autorka odnosi się do recepcji filozofki, przede wszystkim odczytań zaproponowanych przez Katarzynę Szopę (2018) oraz Alison Stone (2006), zastanawiając się, na ile możliwe jest twórcze przekształcenie jej myśli. Jednym z przykładów takiego przekształcenia jest propozycja korporealnego feminizmu Elizabeth Grosz, który jednak nie odpowiada na wszystkie problemy obecne w filozofii Irigaray.
W ramach podsumowania szerzej omówione zostają dwa główne zarzuty wobec feminizmu różnicy – o umniejszanie różnic rasowych i etnicznych oraz o wykluczenie doświadczenia transpłciowości i niebinarności – a także postawione zostaje pytanie o to, na ile metafizyka w filozofii feministycznej może dać podstawę do walki z opresją i nierównościami.
Mindfulness jako nowy ethos korporacji
Authors: Biedziak Jan 
Published: January 2023

Mindfulness z ośrodków terapeutycznych przeniknęło do życia społecznego i jest obecnie jedną z najpopularniejszych metod samopomocy (ang. self-help), która od kilku lat robi zawrotną karierę. Przez dziesięciolecia uważność była dostosowywana do świata zachodniego, a mindfulness opanowało nie tylko dyskurs akademicki związany ze zdrowiem, ale też zaczęło się coraz częściej pojawiać się w dyskusjach o zarządzaniu i przyszłości edukacji.
W pierwszej części artykułu przedstawiam zamysł uważności. Wskazuję na jej nowoczesny, zindywidualizowany oraz sekularny, charakter. W tym celu przywołuję prace Jona Kabat-Zinna, który opracował współczesną wersję uważności i zapoczątkował rewolucję mindfulness. W drugiej ukazuję zaś mindfulness jako styl życia. Poprzez sumienne wykonywanie praktyk staje się ono bowiem niejako współczesną wersją ascezy, która ma prowadzić do ogólnie pojętego dobrostanu. Budzi to skojarzenia z założeniami ascezy protestanckiej oraz ethosu kapitalizmu opisanego przez Maxa Webera.
Na szczególną uwagę zasługuje model wprowadzenia praktyki uważności do firm, o którym traktuje trzecia część artykułu. W kontekście neoliberalnego systemu wpisuje się ono w nurt rozwoju osobistego i stanowi praktyczne rozwiązania dla pracowników. Wytwarza również własną etykę, która przynależy do nurtu indywidualizmu.
Ostatnia część tekstu została poświęcona zagadnieniu McMindfulness, czyli krytyce wprowadzania uważności do firm. W tym podrozdziale prezentuję argumenty wskazujące na wykorzystanie tej techniki w celu podnoszenia zysków firmy i pacyfikacji pracowników.
Wszystkie te elementy ukazują mindfulness jako praktykę dostosowaną do warunków neoliberalnych, która przyjmuje oraz modyfikuje konkretne założenia wywodzące się z ascezy protestanckiej. W konsekwencji sprawia to, że praktykowanie medytacji powoli przestaje być jedynie metodą terapii, a staje się ogólnie obowiązującą normą w dążeniu do dobrostanu psychicznego, choć może także stać się ethosem współczesnych korporacji.