bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inspection of Capparis spinosa essential oils for quality assurance of fish burgers during refrigerated storage
Authors: Shafaghi Rad Mohammad , Nouri Marjan 
Published: September 2023

AbstractFish products are highly perishable as a result of easy spoilage by microorganism populations. The aim of this study is to evaluate the effects of Capparis spinosa essential oils (CSEOs) on physicochemical, sensory, oxidative, and microbiological attributes for fish burgers during refrigerated storage (8 days). For this purpose, CSEOs were prepared by water distillation (CS‐WD), CO2 supercritical fluid (CS‐SCF), subcritical water (CS‐SW) to determine bioactive substances. Total phenol and flavonoid contents and also antioxidant activity were measured in CSEOs extracted by these procedures and phytochemical identification was performed through gas chromatography and mass spectroscopy. These essential oils (EOs) were used at 0.2% in fish burgers, and controls (without additives) and those containing sodium erythorbate were also prepared. Physicochemical, oxidative, microbiological, and sensory functions were examined every 2 days. Phytochemicals were found in CSEOs, and the highest was related to isopropyl isothiocyanate. Addition of CSEOs led to dark, yellow and red colors for fish burgers compared with control. The manufacture of primary and secondary products in oxidation and different microorganisms in samples were significantly decreased by CSEOs compared with controls (p < .05). The antioxidant feature of the burger with CS‐SCF was higher than that of the sample treated with CS‐WD, but these EOs indicated almost the same antimicrobial attributes, and the lowest antioxidant and microbial activities were found for CS‐SW in the fish burger. The sensory results demonstrated that CSEOs did not reduce scores, which maintained the acceptance quality of burgers during refrigerated storage. As a conclusion, CSEOs can be used as effective antioxidants and preservatives in burgers, and sensory acceptance was preserved during storage.
Headspace stir‐bar sorptive extraction combined with gas chromatography–mass spectrometry for trace analysis of volatile organic compounds in Schisandra chinensis Baillon (omija)
Authors: Lee Jae Hoon , Lee Yun‐Yeol , Choi Yun‐Sang , Jang Hae Won 
Published: September 2023

AbstractAnalyzing volatile organic compounds (VOCs) in food is crucial but challenging. Schisandra chinensis Baillon (omija) is an herbal plant with various functional health activities. Previous VOC analyses focused on S. chinensis fruit but not its leaves. Therefore, VOCs in S. chinensis fruit and leaves were analyzed using headspace stir‐bar sorptive extraction (HS‐SBSE)‐GC–MS, and optimal conditions were established. Various factors, such as the sample preparation method, twister stir‐bar type, sample amount, extraction temperature, and extraction time, expected to affect extraction were carefully optimized. Under the optimal conditions, 35 and 40 VOCs were identified in S. chinensis fruit and leaves, respectively. This HS‐SBSE method is capable of rapid analysis and a low contamination rate without requiring organic solvents. These findings provide practical guidelines for HS‐SBSE applications in various food matrices by providing analytical methods for VOC detection.
Cognitive inflexibility is linked to abnormal frontoparietal‐related activation and connectivity in obsessive‐compulsive disorder
Authors: Liu Qian , Gao Feng , Wang Xiang , Xia Jie , Yuan Gangxuan , Zheng Shuxin , Zhong Mingtian , Zhu Xiongzhao 
Published: September 2023

AbstractAlthough it was acknowledged that patients with obsessive‐compulsive disorder (OCD) would exhibit cognitive inflexibility, the underlying neural mechanism has not been fully clarified. Therefore, this study aimed to investigate the neural substrates involved in cognitive inflexibility among individuals with OCD. A total of 42 patients with OCD and 48 healthy controls (HCs) completed clinical assessment and functional magnetic resonance imaging (fMRI) data collection during cued task switching. Behavioral performances and fMRI activation were compared between the OCD group and the HC group. Psychophysiological interactions (PPIs) analyses were applied to explore functional connectivity related to task switching. Pearson correlation was used to investigate the relationships among behavioral performance, fMRI activity, and obsessive‐compulsive symptoms in OCD. The OCD group had a greater switch cost than HCs (χ2 = 5.89, p < .05). A significant difference in reaction time was found during switch (χ2 = 17.72, p < .001) and repeat (χ2 = 16.60, p = .018) between the two groups, while there was no significant difference in group accuracy. Comparison of group differences showed that the OCD group had increased activation in the right superior parietal cortex (rSPL) during task switching, and exhibited increased connectivity of frontoparietal network/default mode network (FPN–DMN; i.e., middle frontal gyrus [MFG]/inferior parietal cortex‐precuneus, MFG‐middle/posterior cingulate gyrus) and within the FPN (inferior parietal cortex‐postcentral gyrus). In the OCD group, the compulsion score was positively correlated with accuracy during switch (r = .405, p = .008, FDRq <.05), and negatively correlated with activation of rSPL (r = −.328, p = .034, FDRq >.05). Patients with OCD had impaired cognitive flexibility and cautious response strategy. The neural mechanism of cognitive inflexibility in OCD may involve increased activation in the rSPL, as well as hyperconnectivity within the FPN and between the FPN and DMN.
The future of corporate insolvency law: A review of technology and AI‐powered changes
Authors: Kamalnath Akshaya 
Published: September 2023

AbstractThe conversation about how artificial intelligence (AI) might affect various areas of law (and other areas of life) has, in recent months, centred around ChatGPT which is just one application of AI. This article takes a broader view and assesses how AI, and technology more broadly, has begun to transform, and will continue to transform corporate insolvency law. While the pandemic has increased the adoption of technology in corporate insolvency processes, there is scope for further transformation. This article aims to survey the technological changes to corporate insolvency law and practice thus far and assess, based on current advances in technology, the potential for further transformation. It advances the argument that technology can improve efficiencies both prior to and during formal insolvency resolution processes. It therefore would be in the interests of every country to facilitate the adoption of technology at various points in the insolvency process. The article takes a cross‐jurisdictional approach to identify tech advances in insolvency law across different countries based on which best practices and guidelines can be outlined.
Public or private gatekeepers in non‐consensual debt restructurings in emerging jurisdictions
Authors: Wan Wai Yee 
Published: September 2023

AbstractIn advanced jurisdictions, the choice of a non‐consensual debt restructuring is between a public or a private gatekeeper model where either the court or the licensed insolvency professional respectively approves a restructuring plan that binds dissenting creditors. In the United States, the only gateway is found in Chapter 11 of the Bankruptcy Code 1978, which requires court approval and gives the debtor a significant say in the outcome. In contrast, in the United Kingdom, there exist four gateways, only two of which require court approval (scheme of arrangement and restructuring plan), while the remaining two (administration and company voluntary arrangement) give significant powers to the insolvency practitioner to decide on the outcome. In emerging jurisdictions such as Mainland China and India, due to path dependency and lack of institutional capacity, the court‐supervised model is chosen as the only or primary gateway to legitimise non‐consensual restructurings though the insolvency practitioner has an important statutory role. Using the two jurisdictions as case studies, this article argues that such a choice has several initial benefits but also leads to several problems, including delays in the restructuring, does not necessarily improve substantive outcomes and does not adequately address the shareholder–creditor and creditor–creditor agency costs. This article proposes that for debt restructuring that involves the sale of the business as a going concern, the private gatekeeper should be able to decide on the sale and the distributions following pre‐bankruptcy entitlements. Recourse to the court as a public gatekeeper should only be used for reorganisation proceedings.
Endoscopic surveillance for familial intestinal gastric cancer in low‐incidence areas: An effective strategy
Authors: Llach Joan , Salces Inmaculada , Guerra Ana , Peñas Beatriz , Rodriguez‐Alcalde Daniel , Redondo Pilar Díez , Cubiella Joaquin , Murcia Óscar , Escalante Maite , Gratacós‐Ginès Jordi , Pocurull Anna , Daca‐Alvarez Maria , Luzko Irina , Sánchez Ariadna , Herrera‐Pariente Cristina , Ocaña Teresa , Carballal Sabela , Elizalde Ignasi , Castellví‐Bel Sergi , Fernández‐Esparrach Glòria , Castells Antoni , Balaguer Francesc , Moreira Leticia 
Published: September 2023

AbstractWhile clinical practice guidelines for hereditary diffuse gastric cancer are well established, there is no consensus on the approach for familial intestinal gastric cancer (FIGC). In low‐incidence gastric cancer (GC) areas such as the United States or most European countries, there are no evidence‐based recommendations on endoscopic assessment in FIGC families. We aim to describe the yield of GC surveillance in these families, and to identify epidemiological risk factors for the development of GC and its precursor lesions. This is a multicenter observational study involving nine tertiary Spanish hospitals, in which all individuals fulfilling FIGC criteria who underwent endoscopic surveillance were included between 1991 and 2020. Forty‐one healthy individuals of 31 families were recruited. The median number of upper gastrointestinal endoscopies per individual was 3 (interquartile range, IQR, 1‐4). The median interval time between tests was 2 years (IQR 1.5‐2.5), and the median follow‐up was 9 years (IQR 3‐14.5). In 18 (43.9%) subjects, a precursor lesion of GC was found during follow‐up, and in 2 (4.9%), an early GC was identified, in which curative treatment was offered. Helicobacter pylori (Hp) infection proved to be independently associated with an increased risk of developing precursor lesions or GC, adjusted by age, gender and follow‐up, with an Odds Ratio of 6.443 (1.36‐30.6, P value .019). We present the first outcomes that support endoscopic surveillance with biopsies and detection of Hp in FIGC families, although the periodicity has yet to be defined.
Oil price shocks and financial stress: Who is the influencer?
Authors: Maghyereh Aktham , Ziadat Salem Adel 
Published: September 2023

AbstractWe contribute to the literature by being the first to examine the direction of causality between the different sources of oil price shocks and financial stress in the global financial markets (OFR), US, other advanced economies (OAE), and emerging markets (EM). Specifically, we aim to empirically answer a key question: Do global oil market shocks drive financial stress, or does financial stress spur oil market shocks? Using a two‐stage methodology based on the structural VAR (SVAR) and entropy‐based analysis over the period January 2000–October 2022, the results show that the links between financial stress and oil shocks are contingent on the type of shock. Within this, oil supply shock is mildly connected to financial stress; oil demand shock is vulnerable to innovation from financial stress; and oil‐specific demand shock has a noticeable time‐variable element wherein the shock prevails at the beginning of the sample and financial stress dominates the transmission at the end of the sample.
Longitudinal associations between social support trajectories and quality of life mediated by depressive symptoms: A 10‐year cohort study of Wenchuan earthquake
Authors: Chen Xiao‐Yan , Shi Xuliang , Li Chao , Fan Fang 
Published: September 2023

AbstractIntroductionPrevious studies on associations between social support and quality of life (QoL) have usually employed a variable‐centered approach, without considering individual variances in time‐varying changes in social support. This study explores trajectories of social support and whether depressive symptoms mediate associations between social support trajectories and QoL 10 years after an earthquake.MethodsSeven hundred and forty‐four Chinese adolescents exposed to the Wenchuan earthquake were surveyed on social support at 6‐, 18‐, and 24‐months and depressive symptoms at 30‐months postearthquake (T30m). They provided valid data on QoL after 10 years of the earthquake (T10y). The latent class growth analysis was used to estimate social support trajectories. Mediation analysis was then conducted to test whether depressive symptoms at T30m mediated associations between social support trajectories and QoL at T10y.ResultsThree trajectories of social support were identified: low decreasing (31.6%), moderate decreasing (55.4%), and persistent high (13.0%) groups. Depressive symptoms significantly mediated the effects of social support trajectories (relative to the low support trajectory) on future QoL (95% CIs: 0.70–1.78 and 1.41–3.37 for moderate decreasing and persistent high groups, respectively).ConclusionsSocial support shows individual differences over time. Moderate and high social support trajectories improve 10‐year QoL partly by reducing depressive symptoms. Therefore, interventions aimed at enhancing social support and reducing depressive symptoms may be more effective in enhancing QoL in the aftermath of disasters.
Ant‐nest type porous scaffold with micro‐struts consisting of carbonate apatite for promoting bone formation and scaffold resorption
Authors: Tan Janice Lay Tin , Shimabukuro Masaya , Kobayashi Mamiko , Kishida Ryo , Kawashita Masakazu , Ishikawa Kunio 
Published: September 2023

AbstractScaffolds having appropriate mechanical strength and providing a proper microenvironment for osteogenesis are expected to be effective alternatives to autografts for bone regeneration. In this study, ant‐nest type porous (ANP) scaffolds consisting of CO3Ap were fabricated using calcium carbonate powder or slurry and two types of polyurethane foam through a dissolution–precipitation reaction. ANP‐type, three‐dimensional, interconnected porous CO3Ap scaffolds were fabricated by burning out the struts of polyurethane foams embedded in CaCO3, followed by compositional transformation from CaCO3 to CO3Ap. The types of polyurethane foam and impregnation methods of CaCO3 into polyurethane form affected the geometry of the resulting ANP structures. Mechanical and in vivo biological performances of these scaffolds relied on the geometry of the ANP structures. The ANP structures displayed had a clear structural advantage in bone regeneration, owing to the promotion of cell and tissue migration throughout the scaffolds. In particular, ANP‐structured scaffolds, which had highest porosity, interconnectivity, and smallest strut thickness, had a mechanical strength comparable to cancellous bone, formed more new bone, were highly resorbed, resulting in cancellous bone‐like bone tissue regeneration at 12 weeks of healing. The results suggest that bone regeneration after the migration of cell and tissue into the entire scaffolds is affected by strut thickness preferentially over porosity and interconnectivity. ANP‐structured CO3Ap scaffolds are attractive for bone regeneration.
Therapeutic potentials of mesenchymal stem cells in the treatment of inflammatory bowel disease in rats
Authors: Ali Mohammed Shuzan , Elbaramawy Azza , Hassan Abd‐Allah Somia , Elkholy Adel , Ibrahim Elsayed Nashwa , Hussein Samia 
Published: September 2023

AbstractInterleukin‐1beta (IL‐1β) and interleukin‐17A (IL‐17A) have strong pro‐inflammatory activities that are involved in inflammatory bowel diseases (IBDs). Mesenchymal stem cell (MSC) therapy is considered a promising treatment for IBD. This study was performed to understand the role of rat Nlrp3 inflammasome, Hmgb1, and pro‐inflammatory cytokines (IL‐1β and IL‐17a) in the pathogenesis of IBD. Also, to evaluate the role of human umbilical cord blood‐MSCs (hUCB‐MSCs) in the management of IBD. The rats were in four groups: normal controls, indomethacin‐induced IBD group, indomethacin‐induced IBD rats that received phosphate‐buffered saline (PBS), and the IBD group that received hUCB‐MSCs as a treatment. The messenger RNA (mRNA) expression levels of rat Nlrp3, Hmgb1, IL‐1β, and IL‐17a were evaluated by quantitative real‐time polymerase chain reaction. Histopathological examination of the small intestinal tissues of the studied rats was performed. There was a significant upregulation of the rat Nlrp3, IL‐1β, IL‐17a mRNA expression (p < 0.001 for the three parameters), and Hmgb1 (p < 0.05) in the untreated IBD group compared to the normal control group. In the MSC‐treated group, IL‐1β, IL‐17a, and rat Nlrp3 mRNA expression significantly decreased compared to both the untreated IBD group and PBS group (p < 0.05 for all). hUCB‐MSCs ameliorated IBD in rats by downregulating the pro‐inflammatory cytokines (IL‐1β and IL‐17a) and other inflammatory mediators such as Hmgb1 and rat Nlrp3.
Translational evaluation of on/off alternative reinforcement cycling
Authors: Smith Sean W. , Greer Brian D. 
Published: September 2023

AbstractCycling between the availability and unavailability of reinforcement for alternative responding has successfully reduced resurgence in basic laboratory evaluations, but this approach represents a marked departure from current standards of care when treating problem behavior, warranting careful translation before its use clinically. Therefore, with extinction arranged for target responding across groups in Phase 2, we evaluated the effects of cycling between the availability and unavailability of differential reinforcement of alternative behavior (DRA) using a computer‐based task with adult humans recruited through Amazon MTurk. Two control groups experienced constant DRA in Phase 2, with one group experiencing a dense DRA schedule and another group experiencing a lean DRA schedule. The cycling DRA group tended to show greater reductions in target responding and improved discrimination in Phase 2 and less target responding across Phases 2 and 3 than the lean DRA and dense DRA groups. These preliminary findings suggest that on/off DRA cycling procedures may produce more desirable treatment outcomes than constant DRA without producing negative side effects; however, further research is needed to confirm these possibilities.
Biceps Pulley Lesions: Diagnostic Accuracy of Nonarthrographic Shoulder MRI and the Value of Various Diagnostic Signs
Authors: Nada Mohamad Gamal , Almalki Yassir Edrees , Basha Mohammad Abd Alkhalik , Libda Yasmin Ibrahim , Zaitoun Mohamed M. A. , M. Abdalla Ahmed A. El‐Hamid , Almolla Rania Mostafa , Hassan Hanan A. , Dawoud Tamer Mahmoud , Eissa Ahmad Hassan Zaki , Alduraibi Sharifa Khalid , Eldib Diaa Bakry , Ziada Yara Mohammed Ahmad Ali 
Published: September 2023

BackgroundThere is limited data in the literature regarding the role of nonarthrographic MRI for detecting biceps pulley (BP) lesions.PurposeTo assess the accuracy of nonarthrographic MRI for detecting BP lesions, and to evaluate the diagnostic value of various MRI signs (superior glenohumeral ligament discontinuity/nonvisibility, long head of biceps (LHB) displacement sign or subluxation/dislocation, LHB tendinopathy, and supraspinatus and subscapularis tendon lesions) in detecting such lesions.Study TypeRetrospective.Population84 patients (32 in BP‐lesion group and 52 in BP‐intact group‐as confirmed by arthroscopy).Field Strength/Sequence1.5‐T, T1‐weighted turbo spin echo (TSE), T2‐weighted TSE, and proton density‐weighted TSE spectral attenuated inversion recovery (SPAIR) sequences.AssessmentThree radiologists independently reviewed all MRI data for the presence of BP lesions and various MRI signs. The MRI signs and final MRI diagnoses were tested for accuracy regarding detecting BP lesions using arthroscopy results as the reference standard. Furthermore, the inter‐reader agreement (IRA) between radiologists was determined.Statistical TestsStudent's t‐tests, Chi‐squared, and Fisher's exact tests, and 4‐fold table test were used. The IRA was calculated using Kappa statistics. A P‐value <0.05 was considered statistically significant.ResultsThe sensitivity, specificity, and accuracy of nonarthrographic MRI for detecting BP lesions were 65.6%–78.1%, 90.4%–92.3%, and 81%–86.9%, respectively. The highest accuracy was noticed for the LHB displacement sign (84.5%–86.9%), and the highest sensitivity was registered for the LHB tendinopathy sign (87.5%). Furthermore, the highest specificity was observed for the LHB displacement sign and LHB subluxation/dislocation sign (98.1%–100%). The IRA regarding final MRI diagnosis and MRI signs of BP lesions was good to very good (κ = 0.76–0.98).Data ConclusionNonarthrographic shoulder MRI may show good diagnostic accuracy for detecting BP lesions. The LHB displacement sign could serve as the most accurate and specific sign for diagnosis of BP lesions.Level of Evidence3Technical EfficacyStage 2
Continental‐scale trends of daily precipitation records in late 20th century decades and 21st century projections: An analysis of observations, reanalyses and CORDEX‐CORE projections
Authors: Belleri Lara , Ciarlo James M. , Maugeri Maurizio , Ranzi Roberto , Giorgi Filippo 
Published: September 2023

AbstractWe apply a methodology to identify and count records (events of unprecedented intensity) in daily precipitation time series to two sets of data: (1) different observational and reanalysis products for recent decades and (2) twenty‐first century projections (RCP8.5 and RCP2.6 scenarios) completed with two regional climate models driven by three global climate models over nine continental‐scale domains. Comparison of the detected (or actual) number of records with the corresponding number theoretically expected in stationary climate conditions (or “reference” number of records) provides indications of trends in daily precipitation extremes, as expected in a changing climate. In particular, we measure deviations from stationary conditions using the ratio of actual to reference records (RAtR) as a basic metric. We find that the observational products provide mixed indications of precipitation record trends across regions, while in the reanalysis products and the model simulations for the historical period the RAtR value shows a prevailing increasing trend with time over most continents. The RAtR shows a consistent and pronounced increase in all RCP8.5 continental‐scale projections, when sustained warming occurs throughout the 21st century, while smaller to no significant trends are found in the RCP2.6 scenario, when the warming stabilizes after about mid‐21st century. These results are indicative of an increase in precipitation extremes with global warming as measured by the higher number of local precipitation events of unprecedented intensity compared to what expected in stationary climate conditions, although a marked variability of this response is found across different regions. Our method can have useful applications in detection and attribution of hydroclimatic extremes and in impact and vulnerability assessment studies.