bluuebunny/crossref_metadata_2025_split huggingface dataset:
Історія створення, минулі та сучасні основні напрямки досліджень та досягнення відділу діабетології ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України»
Authors: Sokolova L.K. , Tkach S.M. 
Published: March 2023

У статті надано основні напрямки наукових досліджень, які були виконані у відділі діабетології (ВД) ДУ «Інститут ендокринології та обміну речовин ім. В.П. Комісаренка НАМН України» (Інститут) з моменту його створення. Особлива увага приділяється вивченню патогенезу, діагностиці, лікуванню та профілактиці судинних і неврологічних ускладнень цукрового діабету (ЦД). Продовжується тісна співпраця співробітників ВД з іншими медичними державними установами з вивчення особливостей перебігу серцево-судинної патології у хворих на ЦД. Численні клінічні дослідження дозволили науково обґрунтувати та впровадити нові методи патогенетичного лікування ЦД та його ускладнень. Майже за 60 років роботи ВД його фахівці надали допомогу більше ніж 40 000 пацієнтам стаціонару та більше ніж 100 000 амбулаторним хворим. Щорічно у ВД отримують високоспеціалізовану медичну допомогу понад 1000 пацієнтів із ЦД з м. Києва та всіх регіонів України. Співробітники ВД є співавторами Українських протоколів надання медичної допомоги хворим на ЦД 1-го типу (ЦД1) та ЦД 2-го типу (ЦД2). Останні 5 років наукова робота ВД в тісній співпрації з відділом фундаментальної та прикладної ендокринології сконцентрована на вивченні молекулярних механізмів формування ускладнень ЦД. Активно вивчаються механізми інсулінорезистентності як ключової ланки патогенезу ЦД2, особливий акцент зроблено на участi АМРК i mTORС1 у розвитку хвороб обміну речовин, супроводжуваних ожирiнням. Вивчається вплив сучасної цукрознижувальної терапії на молекулярні механізми розвитку та прогресування судинних ускладнень ЦД. Значна увага приділяється коморбідним захворюванням. Узагальнено та проаналізовано матеріал щодо запальних процесів, які супроводжують серцево-судинні ускладнення при ЦД. Показана роль ендотеліальної дисфункції в розвитку ускладнень ЦД. Починаючи з 2020 р. у зв’язку з епідемією COVID-19 наукові дослідження ВД доповнилися вивченням патогенетичних ланок між COVID-19 та ЦД. Вивчаються перспективні напрямки лікування ЦД з використанням стовбурових клітин.
Ethnomathematics Exploration of Museum Gedung Arca (State Museum of North Sumatra)
Authors: Safriyanti Safriyanti , Yahfizham Yahfizham 
Published: March 2023

Education and culture are two things that cannot be separated. In education there are cultural values ​​in it. Ethnomatematics is a blend of mathematics and culture. Ethnomatematics can improve students' mathematical abilities. By exploring the ethnomathematics of the Arca Building Museum or the State Museum of North Sumatra, students can get to know the culture and geometric concepts of flat shapes found in building forms and museum collections. The geometry of a flat shape is a form of geometry that has an area and a width. The aim of the research is to improve students' mathematics learning and mathematical abilities through geometric exploration of flat shapes in building shapes, collections, and collection placement in museums. The method I used in my research was qualitative research. The results of the research obtained are finding the geometric concept of flat shapes through the shape of the building, the collection, and the placement of the Museum collection. Ethnomatematics exploration is an alternative to improve mathematics learning and students' mathematical abilities. By exploring the concept of geometric shapes in the form of museum buildings, students can easily understand the mathematics of geometric shapes.
Keywords: Ethnomathematics, Sculpture Building Museum, Flat Shape Geometry
Informasi penjualan pada umkm dapur ummu yahya sebagai media pemasaran kue berbasis website
Authors: Prananingrum Lely , Agustin Sri Kurniasih , Sugiarti Rina , Anggraeni S.Tiwi , Suryansyah Imam , Iswandhari Suci May 
Published: March 2023

Pemerintah pada beberapa negara berkembang memberikan perhatian cukup besar terhadap pemanfaatan TIK (Teknologi Informasi dan Komunikasi), khususnya adopsi e-commerce oleh UMKM (Usaha Mikro Kecil dan Menengah) melalui penerbitan kebijakan dan peraturan untuk membantu mereka dalam mengadopsi teknologi saat ini. Pemerintah Indonesia dalam beberapa tahun terakhir telah mengambil banyak langkah untuk mendukung UMKM guna mulai menggunakan ICT (Information and Communication Technology) dalam menjalankan usahanya. UMKM adalah suatu jenis usaha yang terus berkembang dan dapat memberikan kontribusi positif bagi pertumbuhan ekonomi Indonesia. UMKM perlu bekerja sama dengan instansi terkait atau lembaga yang mampu dalam meningkatan kualitas UMKM di Indonesia. UMKM Dapur Ummu Yahya merupakan kelompok UMKM yang memproduksi dan menjual makanan berupa roti dan kue basah yang bervariasi. Produk khas dari berbagai macam kue hasil olahan Dapur Ummu Yahya adalah Gurih currypuff yang sangat digemari. Usaha yang dirintis oleh Dapur Ummu Yahya merupakan usaha berskala UMKM memiliki prospek pemasaran yang menjanjikan dan dapat meningkatkan pendapatan dari hasil penjualan. Saat ini Dapur Ummu Yahya masih dikelola secara tradisional. Hal ini ditunjukkan belum tersedianya media untuk memasarkan produk hasil olahannya, maka produk tidak dikenal luas dan hanya terbatas pada lingkungan sekitar. Hal ini akan berdampak pada tingkat penjualan yang sulit untuk berkembang. Solusi pertama untuk meningkatkan penjualan adalah dengan membuatkan aplikasi penjualan berbasis website.
Placentomas bovinos como alternativa en tratamientos de anemia ferropénica en perros
Authors: González Suárez Erik David , Rubio Arias Pablo Giovanny 
Published: March 2023

Introducción. En la actualidad son escasos los estudios de la placentofagia en animales y cuáles son los beneficios que podrían conllevar el consumo de placentomas, sean de la misma especie u otra diferente. Objetivo. Esta investigación tiene como objetivo evaluar el efecto que tienen los placentomas bovinos en tratamientos de anemias por deficiencia de hierro en perros, el estudio se llevó a cabo en la ciudad de Guayaquil. Materiales y métodos. Los placentomas fueron extraídos del centro de faenamiento de la ciudad de Guayaquil, siendo cocidos completamente a temperatura de 160° Fahrenheit y luego deshidratados durante 8 horas, para pulverizarlos y proceder a encapsularlas y suministrarle a un grupo experimental de los perros (grupo A), mientras al grupo testigo (grupo B), se le suministro tabletas multivitamínicas existente en el mercado, las cuales contenían oligoelementos como el hierro en su composición. Resultados. Los resultados obtenidos en esta investigación fueron que el 60% de los animales que se le suministro los placentomas salieron de su amenia de tipo ferropénica. Conclusiones. Se demostró que el consumo de los placentomas si tiene efectos favorables en pacientes con anemias por deficiencia de hierro.
Reporte de caso: dilatación vólvulo gástrico y peritonitis biliar en un canino de 5 meses
Authors: Montalvo Balarezo Alejandro Oswaldo , Armas Ariza Juan Carlos , Chacón Jordan Amanda Dayana 
Published: March 2023

Introducción. La dilatación vólvulo gástrico (DVG) en los caninos es un síndrome agudo, de curso emergente y que compromete la vida de los pacientes mientras que la peritonitis biliar es una alteración infrecuente y cuyo pronóstico suele depender de la causa subyacente. Objetivo. Describir el protocolo diagnóstico y terapéutico aplicado en el caso de un paciente canino que acudió a consulta por anorexia y dilatación abdominal aguda. Metodología. Mediante radiografía, se diagnosticó probable DVG en el paciente y se realizó una estabilización inicial con fluidoterapia, oxigenoterapia, descompresión gástrica mediante trocarización percutánea y sondaje orogástrico. El paciente se mantuvo estable tras este manejo inicial, pero tras 72 horas, presentó líquido libre en la región hepato-diafragmática, atribuible a peritonitis biliar. Durante la resolución quirúrgica se evidenció colecistitis necrotizante y congestión en el lóbulo cuadrado por lo que se realizó colecistectomía y lobectomía hepática parcial empleando bisturí armónico (ETICON GEN 11). Se colocó un drenaje activo cerrado y el paciente permaneció en hospitalización tres días con tratamiento antibiótico, analgésico y protectores gástricos, para su posterior alta domiciliaria. Resultados. A los diez días de iniciado el manejo en casa con antibioterapia, analgesia y protectores gástricos., el paciente presentó una cicatrización adecuada y se concedió el alta médica definitiva. La adecuada estabilización prequirúrgica junto con el manejo postquirúrgico (mediante la antisepsia en la herida y la terapia farmacológica) fueron fundamentales para la resolución del caso clínico pese a la complicación que pudo acarrear la peritonitis biliar. Conclusión. En los casos de DVG es fundamental la evaluación de la presión arterial y la lactatemia como factores relevantes para mejorar el pronóstico postquirúrgico. Además, es imprescindible considerar las alteraciones en otros órganos y evaluarlos para descartar (como la peritonitis biliar en este caso). Área de la ciencia: medicina veterinaria
Tratamento conservador da polpa em dentes permanentes vitais com rizogênese incompleta – uma revisão de literatura
Authors: Veras Pedryna Maria Oliveira , Oliveira Daisy Coelho , Rodrigues Jéssica da Silva , Paiva Leyriane Mendes , Costa Marinna Barroso Maciel , Cunha Clarice Fernandes Eloy da Costa , Vivacqua Flávia Darius 
Published: March 2023

O objetivo deste estudo foi realizar uma revisão de literatura acerca dos tratamentos conservadores propostos para os casos de dentes permanentes jovens, com rizogênese incompleta e vitalidade pulpar, bem como os materiais mais utilizados para este fim. Trata-se de uma revisão integrativa da literatura. Os estudos foram criteriosamente avaliados e coletados através de buscas nas plataformas de pesquisa da Pubmed, Scielo, BVS e Google Scholar, utilizando os seguintes termos: “Conservative Treatment”, “Pulp Capping” e “Endodontics”. Após a busca nos portais eletrônicos foram encontrados 67 artigos no qual foi realizada a leitura de títulos e resumos, respeitando os critérios de inclusão e exclusão, elegendo-se assim, 43 estudos para análise detalhada. Após a avaliação do texto completo, excluíram-se 22, restando 21 artigos que compuseram esta revisão. As técnicas atualmente descritas na literatura para este fim são: o capeamento pulpar direto, curetagem pulpar e pulpotomia, sendo os principais materiais utilizados para a realização desses procedimentos o Hidróxido de Cálcio e o Agregado de Trióxido Mineral (MTA). Os estudos mostram não haver diferença significativa entre ambos, com relação a resposta pulpar e a continuidade da formação apical. Conclui-se que o capeamento pulpar direto é o procedimento atualmente mais realizado e viável em casos de dente permanente jovem, com ápice incompleto. Dentre os materiais de escolha, os mais utilizados para esse procedimento são o hidróxido de cálcio e o MTA, contudo o MTA, tem apresentado propriedades biológicas mais relevantes.
KINERJA DINAS KOMUNIKASI DAN INFORMATIKA KOTA PONTANAK DALAM PELAYANAN INFORMASI BERBASIS ELEKTRONIK JEPIN (JENDELA PONTIANAK INTEGRASI)
Authors: Ismail Ismail , Azizah Nur Laili 
Published: March 2023

Jendela Pontianak Integrasi (JEPIN) is an electronic-based public information service system that is a product of the Pontianak City Communication and Informatics Office. JEPIN aims to be a forum for information about the needs of the community, the Pontianak city government, and community complaints. This research is based on the findings of obstacles experienced by the agency in the application of the system through secondary data. The purpose of this research is to find out the performance of the Pontianak City Communication and Informatics Office in organizing JEPIN information services. This research is qualitative descriptive research with inductive approach (from special to general) Interview, observation and documentation data collection techniques. Data analysis techniques used include data reduction, data presentation and conclusion drawing. The results of research at the Department of Communication and Informatics Pontianak city showed that the performance of the office in electronic-based information services is still not running well, this is seen from 5 (five) dimensions of the assessment of the performance of the office which 4 (four) of them did not meet the target that has been determined. Namely productivity, quality of service, responsiveness, and responsiveness, only the dimension of accountability meets the targeted service.
Keyword: Jendela Pontianak Integrasi (JEPIN), Performance, Information Services
EFEKTIVITAS PELAYANAN PENERBITAN KARTU KELUARGA MELALUI TANDA TANGAN ELEKTRONIK DI DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL KOTA SOLOK PROVINSI SUMATERA BARAT
Authors: Rizqiqa Edtyva Dwirahmi , Amalia Rizki 
Published: March 2023

Electronic signatures are an innovation of the population acceleration program, aimed at making population documents more efficient without having to meet face-to-face. There are still damaged documents in the issuance of family cards and the limited number of employees who understand services through electronic signatures are problems. The purpose of the study was to determine the effectiveness of family card issuance services through electronic signatures, obstacles and efforts to overcome them. The method used is descriptive qualitative inductive approach. Data collection techniques were carried out by triangulation which included in-depth interviews (10 informants), observation and documentation. In this paper, an analysis of the effectiveness of family card issuance services through electronic signatures is carried out with the indicators studied, namely (1) Production or productivity, (2) Quality, (3) Efficiency, (4) Flexibility, and (5) Satisfaction. (Gibson and Steers in Sumaryadi (2005:107)).The results showed that the effectiveness of family card issuance services through electronic signatures had been implemented quite well, but still needed improvements in efficiency indicators. Barriers to the effectiveness of family card issuance services through electronic signatures, namely (1) Unstable Network Connections, (2) Lack of Human Resources, (3) Lack of supporting facilities. Efforts are being made to overcome obstacles, namely (1) repairing the server network that is experiencing disruptions, (2) Involving existing employees in training or technical guidance, (3) Adding supporting facilities. Suggestions from the research: (1) reform the system related to optimizing the central network as the organizer of the Electronic Signature policy, (2) increase the number of employees and (3) improve infrastructure facilities.
Keywords: Electronic Signature, Effectiveness, Family Card.
Analisis Perilaku Korupsi Aparatur Pemerintah Di Indonesia (Studi pada Pengelolaan Bantuan Sosial Di Era Pandemi Covid-19)
Authors: Setiawan Irfan , Jesaja Christin Pratami 
Published: March 2023

Korupsi merupakan suatu tindakan menyimpang untuk mendapatkan kekayaan dan keuntungan pribadi menggunakan uang rakyat atau negara secara ilegal dengan menyalahgunakan kekuasaan yang diberikan. Salah satu kasus yang terjadi belakangan ini dan cukup memprihatinkan ialah kasus korupsi bantuan sosial di masa pandemi virus corona. Tujuan penulisan ini adalah menganalisis perilaku korupsi bantuan sosial oleh para aparatur pemerintahan di tengah pandemi virus corona, Penanganan tindakan korupsi aparatur pemerintahan Indonesia, dan Upaya untuk meminimalisir tindakan korupsi bantuan social di Indonesia. Penelitian ini memadukan konsep Kast, Rosenzweig, 1970 mengenai perilaku yang didasarkan motivasi, konsep McClelland, 1985 mengenai dorongan dasar motivasi & konsep GONE dari Jack Bologne, 1993 mengenai penyebab korupsi. Metode penulisan yang digunakan adalah metode deskriptif dan kepustakaan (pengumpulan data pustaka) dengan melakukan analisis secara sistematis dari semua data terkumpul yang berkaitan dengan masalah dalam penulisan, disamping itu penulis juga mewawancarai tenaga ahli baik dari penyuluh anti korupsi maupun pengkaji masalah sumber daya aparatur. Hasil penulisan ini menunjukkan bahwa korupsi merupakan masalah yang sangat besar karena dapat mengganggu pertumbuhan dan pembangunan negara, serta butuh penanganan serius untuk mengatasi atau meminimalisir keberadaannya. Korupsi bisa terjadi karena cara pandang seseorang akan kekayaan yang salah, ketamakan, adanya peluang, kebutuhan, penyalahgunaan kekuasaan, tidak adanya nilai-nilai integritas dan nasionalisme, ketidaktegasan hukum, dan pandangan terhadap hukum. Salah satu contohnya ialah kasus korupsi penyalahgunaan dana bantuan sosial saat pandemi virus corona yang menyebabkan kerugian besar. Upaya yang dapat dilakukan untuk meminimalisir hal ini dapat dilakukan dengan memberi edukasi sejak dini akan nilai-nilai anti korupsi, menegakkan hukum yang berlaku secara tegas, dan menyosialisasikan kepada masyarakat tentang mekanisme pengaduan dan pelaporan apabila mengetahui terjadinya tindakan korupsi.

Kata Kunci: Perilaku Korupsi, Aparatur Pemerintah, Bantuan Sosial, Pandemi COVID-19
Using multiple lines of evidence to assess recovery potential of a warm water fish population in a cold water impacted river
Authors: Tonkin Zeb , Koehn John , Commens Sarah , Hackett Graeme , Harris Annique , Kitchingman Adrian , Lyon Jarod , Moloney Paul , Todd Charles , Woodhead Jon 
Published: March 2023

IntroductionHumans have substantially altered landscapes across the globe, generating novel ecosystems with varying states of modification. The principles of reconciliation ecology emphasise that such novel ecosystems must also be considered for conservation outcomes. This requires an understanding of how anthropogenic habitat alterations in a novel ecosystem may disrupt life cycle processes of key biota, thereby enabling the development of management strategies that may bypass or ameliorate potential bottlenecks in life history stages. We explore this by assessing Murray cod (Maccullochella peelii), a native fish species of considerable cultural, recreational and conservation significance in a severely altered river reach in south-eastern Australia. This species was considered to have disappeared in the reach following alterations to the river’s thermal profile (cold water pollution - CWP), but instead has persisted.MethodsWe examined the life cycle of Murray cod and use multiple lines of evidence to assess the impacts of CWP pollution on key processes such as adult migration, recruitment and juvenile survival. We also evaluated the potential for recovery and persistence of the species in this novel system using mitigation measures such as flow management and stocking and opportunistically tested their effectiveness.ResultsWe found the key impact pathway of CWP on the Murray cod population is via its effects on the key processes influencing natural recruitment. Conversely, the effects of CWP on emigration and survival of larger juveniles and adults did not appear to be a major bottleneck for the population. Using a stochastic population model, we showed that the population could be sustained by stocking and opportunistic water management while still meeting irrigation demands. Monitoring to test our recommendations showed natural recruitment and improved survival of stocked fish during years with limited flow releases, thereby corroborating our predictions.DiscussionOur use of multiple lines of evidence to assess a species’ responses to impacts of habitat alteration in a novel ecosystem enabled the formulation of recommendations for management that could then be tested. The success of such actions add to the growing body of literature that shows species of conservation significance can be maintained in novel ecosystems which should be specifically considered within the context of conservation planning across the landscape.
Incremental healthcare cost burden in patients with atrial flutter only
Authors: Kim Kathryn M. , Kim Steven Y. , Schulman Kathy L. , Kim Michael H. 
Published: March 2023

BackgroundLimited information is available on the costs related to atrial flutter only. This study provides a comprehensive estimate of the cost in patients with atrial flutter only versus matched patients without any atrial arrhythmia.MethodsPatients over 20 years of age with a minimum of one inpatient or two outpatient diagnosis codes for atrial flutter in 2005 and a minimum of 12 months of continuous enrollment pre- and post-index were identified using the MarketScan Commercial and Medicare databases. Atrial flutter patients were propensity matched to patients without atrial arrhythmias. Total costs for each patient for 12 months post-index were calculated. National cost was estimated using the projected prevalence of atrial flutter for 2010.ResultsA total of 1,042 patients with atrial flutter only were successfully matched with comparison patients. For atrial flutter patients compared to matched controls without atrial arrhythmias, total mean annual cost per patient was 81% higher ($23,008 vs. $12,717) and mean annual inpatient expenditure was 214% higher ($8,518 vs. $2,713). When applied to national atrial flutter prevalence data, total incremental cost burden was estimated to be $687.9 million per year more than patients without atrial arrhythmias, primarily due to cardiovascular specific expenditure ($377 million, 55% of total) with 58% ($218.5 million) of the increased inpatient expenditure due to cardiovascular specific admissions and $159 million (23%) for atrial flutter specific care. Sex-related differences were also present in atrial flutter only patients.ConclusionAlthough atrial flutter-only patients are less prevalent than atrial fibrillation patients, the national incremental cost burden in atrial flutter is substantial on a per-patient level.
Examining the influence of substance use on mental health rating during COVID-19: A Canadian perspective
Authors: Sivashankar Yadurshana , Chen Ze Lin 
Published: March 2023

IntroductionSubstance use and mental health symptoms (e.g., depression and anxiety) have increased during the COVID-19 pandemic, partly due to implementation of physical distancing measures aimed at containing the spread of the SARS-CoV-2 virus. However, there is limited pandemic-specific research that has examined the relationship between substance use and mental health with other correlates of well-being, including life satisfaction and social confidants.MethodsIn the current study, we used ordered logistic regression analyses to examine whether a greater frequency of substance use (e.g., alcohol, cannabis, and opioids) during the pandemic predicted poorer ratings of self-reported mental health in a large sample of Canadians aged 15 to 64 years. We further considered whether life satisfaction and number of social confidants interacted with substance use to influence mental health, and stratified the models by sex and personal feelings of shame surrounding the use of substances (i.e., high and low shame).ResultsFindings indicated that frequency of substance use was significantly associated with increased odds of reporting poorer mental health for males and females exhibiting both low and high shame. In females reporting low shame, we found that as frequency of cannabis use increased, life satisfaction has a much greater positive association with mental health. Whereas, in females disclosing high shame, maintaining social relations was particularly important to benefit the mental health of current users of opioids, relative to past and non-users. No such interaction was found in males.DiscussionOverall, the findings of the current study showed the negative mental health consequences of substance use during COVID-19 in a large Canadian sample, and most importantly revealed a critical sex difference in the way in which social determinants interact with substance use to influence mental health.