bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction of a Ce‐UiO‐66/MCo2O4 Heterojunction for Photocatalytic Cr(VI) Detoxification Through a p‐n Junction Formation Mechanism
Authors: Hosseinpour Mahdi , Khosroshahi Negin , Safarifard Vahid 
Published: May 2023

AbstractHeterojunction engineering in catalyst structures is a promising approach to solve some restrictions in photocatalyst design, such as a narrow photoabsorption range and rapid recombination of photogenerated charge carriers. In this work, MCo2O4 (M=Mn, Zn, Fe) was synthesized using a template method. The porous MCo2O4 was composited by Ce‐UiO‐66 to form a heterojunction structure. The resultant material Ce‐UiO‐66/MCo2O4 had a hierarchically porous architecture and was used as a photocatalyst for Cr(VI) reduction. The coupling of Ce‐UiO‐66 and MCo2O4 resulted in a p‐n junction mechanism for charge carrier transfer. The Ce‐UiO‐66/MCo2O4 heterojunctions exhibited high Cr(VI) reduction ability under visible light irradiation over 120 min. The highest Cr(VI) photoreduction rate of the heterojunction is 14 times that of Ce‐UiO‐66. The binary heterojunction maintains high photoreduction efficiency (100 %) of Cr(VI) after four cycling tests showing excellent photocatalytic stability.
Dental cleaning behavior and related factors among hemodialysis patients in the West of Iran: A cross‐sectional study
Authors: Fallahi Arezoo , Hajimam Aveen Fattah , Rahmani Azam , Allahqoli Leila , Schmalz Gerhard , Nemat Babak 
Published: May 2023

AbstractObjectivesOral health‐related behaviors in hemodialysis patients are reduced, potentially leading to adverse consequences. The aim of the present study was to evaluate dental cleaning behavior (DCB) and related factors among hemodialysis patients.MethodsThis cross‐sectional study was carried out in Sanandaj city, in the west of Iran in 2022. Using the census method, 115 hemodialysis patients from the dialysis center of Tohid Hospital were recruited. Data were gathered by a three‐section questionnaire. The first section included demographic characteristics, the second section involved variables related to the health belief model (HBM), and the third section assessed stages of DCB change based on the trans‐theoretical model. Analysis of data was done by assessing frequency, descriptive and inferential statistics such as t test, correlation coefficient, and regression.ResultsOnly 26.1% of participants reported DCB, defined as tooth brushing at least twice daily; 30.4% were in the precontemplation stage, 26.1% in contemplation, and 17.4% in the preparation stage. Perceived self‐efficacy was lower among patients who did not perform DCB. The odds of DCB increased with perceived self‐efficacy (odds ratio [OR] = 1.51, 95% confidence interval [CI] = 1.19–1.92, p < .05), cues to action (OR = 1.63, 95% CI = 1.03–2.55, p < .05), and decreased with perceived barriers (OR = 0.68, 95% CI = 0.47–0.97, p < .01).ConclusionsDCB of patients on hemodialysis requires improvement. Perceived self‐efficacy, cues to action, and perceived barriers constructs of the HBM should be considered in interventional programs targeting to increase oral health as well as in future research in the field.
Regulation of Polymerization Kinetics to Improve Crystallinity of Carbon Nitride for Photocatalytic Reactions
Authors: Wang Chong , Xiao Hongxiang , Lu Yichun , Lv Jinliang , Yuan Zhanhui , Cheng Jiajia 
Published: May 2023

AbstractCarbon nitride (CN) polymers exhibit tunable and fascinating physicochemical properties and are thus an essential class of photocatalytic materials with potential applications. Although significant progress has been made in the fabrication of CN, the preparation of metal‐free crystalline CN via a straightforward method remains a considerable challenge. Herein, we describe a new attempt to synthesize crystalline carbon nitride (CCN) with a well‐developed structure through regulation of the polymerization kinetics. The synthetic process involves the pre‐polymerization of melamine to remove most of the ammonia and further calcination of the pre‐heated melamine in the presence of copper oxide as an ammonia absorbent. Copper oxide can decompose the ammonia produced by the polymerization process, thereby promoting the reaction. These conditions facilitate the polycondensation process while avoiding carbonization of the polymeric backbone at high temperatures. Owing to the high crystallinity, nanosheet structure, and efficient charge‐carrier transmission capacity, the as‐prepared CCN catalyst shows much higher photocatalytic activity than its counterparts. Our study provides a novel strategy for the rational design and synthesis of high‐performance carbon nitride photocatalysts by simultaneously optimizing polymerization kinetics and crystallographic structures.
Summary of validation considerations with real‐life examples using both qualitative and semiquantitative flow cytometry assays
Authors: Devitt Katherine A. , Oldaker Teri , Shah Kalpesh , Illingworth Andrea 
Published: May 2023

AbstractIn the clinical laboratory, flow cytometry assays are critical to providing diagnostic and prognostic information to the treating clinicians. A validation or verification provides confidence that the assay will yield reliable results that can be trusted to make critical medical decisions. The following performance specifications should be included in a validation for laboratory developed tests as needed: accuracy (or trueness), precision (reproducibility and repeatability), detection capability, selectivity, reference range, and sample and reagent stability. We define these terms and present our approach to validation of several common flow cytometry assays, including examples of a leukemia/lymphoma assay and a paroxysmal nocturnal hemoglobinuria (PNH) assay.
Recent trends of potential medicinal uses of rice bran with its composition and bibliographic analysis
Authors: Kumar Vikram , Singh Pooja , Sharma Asha 
Published: May 2023

AbstractRice is an essential crop, growing in nearly every part worldwide. Grains are the most common rice plant part consumed as food; however, other plant parts also have some significant values apart from grains. Rice bran is the outer layer of the rice grain, an excellent source of various phenolic, flavonoid, and phytoactive compounds. This review article discusses the various compounds found in rice bran with their structure and properties. Different medicinal properties of rice bran are also discussed in this review article. Several constituents of rice bran show anticancerous activity through various mechanisms like cell cycle arrest and regulation of apoptotic factors. Anti‐inflammatory, antidiabetic, antihypertensive, and cholesterol‐lowering are the other activities of rice bran, briefly explained in the article, along with their mechanism of action. A bibliographic network, including keyword bibliography analysis and a three‐field plot, has also been discussed to show the trends and network of common keywords in the recently published documents in the Scopus database. Overall, this review explores the rice bran compositions with their structures, activity, and various medicinal uses of rice bran, which can be proven an efficient oil source for nutritional purposes.
Short‐term outcomes of heart transplant patients bridged with Impella 5.5 ventricular assist device
Authors: Haddad Osama , Sareyyupoglu Basar , Goswami Rohan M. , Bitargil Macit , Patel Parag C. , Jacob Samuel , El‐Sayed Ahmed Magdy M. , Leoni Moreno Juan Carlos , Yip Daniel S. , Landolfo Kevin , Pham Si M. 
Published: May 2023

AbstractAimsWe sought to investigate the outcomes of heart transplant patients supported with Impella 5.5 temporary mechanical circulatory support.Methods and resultsPatient demographics, perioperative data, hospital timeline, and haemodynamic parameters were followed during initial admission, Impella support, and post‐transplant period. Vasoactive‐inotropic score, primary graft failure, and complications were recorded. Between March 2020 and March 2021, 16 advanced heart failure patients underwent Impella 5.5 temporary left ventricular assist device support through axillary approach. Subsequently, all these patients had heart transplantation. All patients were either ambulatory or chair bound during their temporary mechanical circulatory support until heart transplantation. Patients were kept on Impella support median of 19 days (3–31) with the median lactate dehydrogenase level of 220 (149–430). All Impella devices were removed during heart transplantation. During Impella support, patients had improved renal function with median creatinine serum level of 1.55 mg/dL decreased to 1.25 (P = 0.007), pulmonary artery pulsatility index scores increased from 2.56 (0.86–10) to 4.2 (1.3–10) (P = 0.048), and right ventricular function improved (P = 0.003). Patients maintained improved renal function and favourable haemodynamics after their heart transplantation as well. All patients survived without any significant morbidity after their heart transplantation.ConclusionsImpella 5.5 temporary left ventricular assist device optimizes care of heart transplant recipients providing superior haemodynamic support, mobility, improved renal function, pulmonary haemodynamics, and right ventricular function. Utilizing Impella 5.5 as a direct bridging strategy to heart transplantation resulted in excellent outcomes.
FcγR‐dependent apoptosis regulates tissue persistence of mucosal and connective tissue mast cells
Authors: Wu Tongqian , Yan Shirong , Yeh Yu‐Wen , Fang Yu , Xiang Zou 
Published: May 2023

AbstractRodent mast cells can be divided into two major subtypes: the mucosal mast cell (MMC) and the connective tissue mast cell (CTMC). A decade‐old observation revealed a longer lifespan for CTMC compared with MMC. The precise mechanisms underlying such differential tissue persistence of mast cell subsets have not been described. In this study, we have discovered that mast cells expressing only one receptor, either FcγRIIB or FcγRIIIA, underwent caspase‐independent apoptosis in response to IgG immune complex treatment. Lower frequencies of CTMC in mice that lacked either FcγRIIB or FcγRIIIA compared with WT mice were recorded, especially in aged mice. We proposed that this paradigm of FcγR‐mediated mast cell apoptosis could account for the more robust persistence of CTMC, which express both FcγRIIB and FcγRIIIA, than MMC, which express only FcγRIIB. Importantly, we reproduced these results using a mast cell engraftment model, which ruled out possible confounding effects of mast cell recruitment or FcγR expression by other cells on mast cell number regulation. In conclusion, our work has uncovered an FcγR‐dependent mast cell number regulation paradigm that might provide a mechanistic explanation for the long‐observed differential mast cell subset persistence in tissues.
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production
Authors: Duan Zhaojun , Ma Longfei , Jin Jing , Ma Lingyu , Ye Lilin , Wu Jianguo , Luo Yunping 
Published: May 2023

AbstractEffective vaccines that function through humoral immunity seek to produce high‐affinity antibodies. Our previous research identified the single‐nucleotide polymorphism rs3922G in the 3ʹUTR of CXCR5 as being associated with nonresponsiveness to the hepatitis B vaccine. The differential expression of CXCR5 between the dark zone (DZ) and light zone (LZ) is critical for organizing the functional structure of the germinal center (GC). In this study, we report that the RNA‐binding protein IGF2BP3 can bind to CXCR5 mRNA containing the rs3922 variant to promote its degradation via the nonsense‐mediated mRNA decay pathway. Deficiency of IGF2BP3 leads to increased CXCR5 expression, which results in the disappearance of CXCR5 differential expression between DZ and LZ, disorganized GCs, aberrant somatic hypermutations, and reduced production of high‐affinity antibodies. Furthermore, the affinity of IGF2BP3 for the rs3922G‐containing sequence is lower than that for the rs3922A counterpart, which may explain the nonresponsiveness to the hepatitis B vaccination. Together, our findings suggest that IGF2BP3 plays a crucial role in the production of high‐affinity antibodies in the GC by binding to the rs3922‐containing sequence to regulate CXCR5 expression.
Towards (C,C)‐cyclometalated N‐(9‐alkylfluorenyl)NHC Ruthenium Complexes for Z‐selective Olefin Metathesis
Authors: Gajda Katarzyna , Sytniczuk Adrian , Vendier Laure , Trzaskowski Bartosz , Lugan Noël , Kajetanowicz Anna , Bastin Stéphanie , Grela Karol , César Vincent 
Published: May 2023

AbstractThree Hoveyda‐Grubbs complexes supported by N‐(9‐alkylfluorenyl)imidazol‐2‐ylidene ligands (alkyl=methyl, ethyl or benzyl) have been synthesized. With the aim to generate chelating, cyclometalated (C,CNHC) ruthenium complexes for Z‐selective olefin metathesis, the C(sp3)‐H activation of the dangling alkyl group has been studied. While the methyl derivative leads to the expected cyclometalated complex, a C(sp2)‐H activation of the fluorenyl moiety and no evolution/transformation are observed for the ethyl and benzyl derivatives, respectively. Although highly fragile under catalytic conditions, the cyclometalated complex leads to Z/E stereoselectivity up to 94/6. An unprecedented insertion of the alkylidene moiety into the Ru‐CNHC bond leading to ruthenium N‐heterocyclic olefin complexes is also observed and supported by calculations of the corresponding reaction pathway.
Investigation of phase difference and separation distance effects in the design of a dual flapping hydrofoil turbine
Authors: Jeong Dasom , Nguyen Le Dang Hai , Ko Jin Hwan 
Published: May 2023

AbstractIn this study, a parametric analysis was conducted for the design of a suggested dual flapping hydrofoil turbine. A Navier–Stokes‐based computational fluid dynamics code was utilized for the analysis while varying the pitch angle, reduced frequency, separation distance, and phase difference. The smallest pitch angle of 60° and the reduced frequency of 0.1 among the given ranges of the parameters were fixed for the first parametric analysis. After an assessment, the 90° front‐lead with the longest distance of 6c and the 90° rear‐lead with the shortest distance of 2c were chosen for further parametric analysis based on a suggested performance indicator and a margin for improvement. It was derived from a subsequent parametric analysis that a 70° pitch angle, 0.12 reduced frequency, and a 4c distance for the 90° front‐lead was the final optimum with 59.48% efficiency and 55.44% fluctuation according to the performance indicator as well as the system length and power balance of dual hydrofoils.
Valedictory lecture: We are rooted but we flow
Authors: Braidotti Rosi 
Published: May 2023

AbstractThis is the text of the valedictory lecture that Rosi Braidotti delivered in June 2022, to mark the retirement from her academic position at Utrecht University. It was conceived as a spoken text and written within the rhetorical tradition of valedictory speeches. The text traces the different phases of Braidotti's career in terms of institutional practice and theoretical developments over the last 40 years. Combining academic analysis with deep ethical passion, Braidotti argues for the need of combining critique with creativity, and radicalism with excellence, to highlight the relevance of the new humanities for our troubled world. Ending on a high note of affirmative ethics, Braidotti calls for a more inclusive, diverse and critical practice of the humanities, as a living experiment of what we are capable of becoming.
Assessing anatomical distribution of atopic dermatitis identifies a cluster of patients with late onset and low risk of asthma and allergy: An observational study
Authors: Ali Zarqa , Anderson Kathryn , Andersen Anders D. , Dahiya Priyanka , Zibert John R. , Thomsen Simon F. 
Published: May 2023

AbstractBackground and AimsA better understanding of distinct subgroups in atopic dermatitis (AD) is warranted. The aim was to identify and determine characteristics of clusters based on anatomical location of AD.MethodsIn this 8‐week, observational, decentralized study, patients with AD completed a baseline questionnaire about anatomical location and severity of AD, and a principal component analysis (PCA) was applied to identify clusters. The Patient‐Oriented Eczema Measure (POEM) was completed weekly and photographs of affected body areas were captured by the participants' own smartphones. From the weekly photographs, the AD severity was evaluated using the intensity part of the SCORing Atopic Dermatitis.ResultsFifty‐five participants were recruited, of which 53 completed the baseline questionnaire with a mean POEM of 14.5 (SD: 5.6). The PCA analysis revealed three clusters, with AD predominantly on the shins, knees, and genitals (Cluster 1), with involvement of the upper body (Cluster 2), and with AD on the hands and feet (Cluster 3). Cluster 1 had a lower mean POEM score (11.12, SD: 5.3) compared with Clusters 2 (12.64, SD: 4.5) and 3 (15.98, SD: 4.7), respectively (p = 0.007). Further, Cluster 1 had the highest age of AD onset (mean 9.5 vs. 2.5 and 4.7 years, p = 0.02) and the lowest proportion of asthma/allergy (47% vs. 82% and 90%, p = 0.01).ConclusionThree clusters of patients with AD based on affected body areas were identified. The cluster with involvement of legs and genitals was characterized by the oldest age of AD onset and the lowest prevalence of asthma/allergy.
Multiple indicators of violence against female sex workers and its associated factors in Ghana: Evidence from the 2015 integrated bio‐behavioral surveillance survey cross‐sectional study
Authors: Ayamah Paul , Aheto Justice Moses K. , Atuahene Kyeremeh S. , Annang Dennis A. , Nartey David T. , Amuasi Sue A. , Abrefa‐Gyan Tina 
Published: May 2023

AbstractBackground and AimsViolence against female sex workers (FSWs) is a widespread phenomenon, especially in African nations like Ghana where sex work is outlawed primarily because of the pervasive worldview that sex work is a contravention of morality. Violence against FSWs deters them from accessing critical health services and heightens their risk of STIs including HIV infection. The study examined the prevalence and the associated factors of multiple indicators of violence against FSWs.MethodsThe study utilized a cross‐sectional secondary data from the 2015 Integrated Bio‐Behavioral Surveillance Survey conducted among FSWs and their nonpaying partners by Ghana AIDS Commission. We analysed data on a total of 4279 participants. Bivariate, and multivariable logistic regression analyses were utilized to identify factors associated with physical and sexual violence against FSWs. Data were analysed using Stata version 15.ResultsOf the 4279 FSWs, 433 (10%) and 1059 (25%) suffered physical and sexual violence, respectively. The predictors of physical violence are being a seater (adjusted odds ratio [aOR] = 0.53, 95% confidence interval [CI]: 0.36–0.74), aged ≥40 (aOR = 0.23, 95% CI: 0.08–0.64), nonuse of drugs (aOR = 0.56, 95% CI: 0.44–0.70), not using alcohol before sex (aOR = 0.69, 95% CI: 0.56–0.86) and petty business (aOR = 1.39, 95% CI: 1.05–1.82). Sexual violence was predicted by those aged 31–40 (aOR = 0.68, 95% CI: 0.49–0.94) and age ≥40 (aOR = 0.38, 95% CI: 0.22–0.66), currently married (aOR = 0.42, 95% CI: 0.27–0.67), having no living children (aOR = 0.69, 95% CI: 0.51–0.94), nonuse of drugs (aOR = 0.80, 95% CI: 0.68–0.94), and not using alcohol before sex (aOR = 0.74, 95% CI: 0.63–0.86). Region was associated with both physical and sexual violence. Both physical and sexual violence had negative consequences on consistency of condom use and condom failure among FSWs.ConclusionPhysical and sexual violence against FSWs is pervasive, and a critical public health issue in Ghana. The identified associated factors could be considered as part of an overall strategy aimed at addressing the menace.
Comparison of echocardiographic pulmonary flow Doppler markers in patients with massive or submassive acute pulmonary embolism and control group: A cross‐sectional study
Authors: Bigdelu Leila , Daloee Mahdi Hasanzadeh , Emadzadeh Maryam , Parsa Leila , Najafi Mahnaz , Baradaran Rahimi Vafa 
Published: May 2023

AbstractBackground and AimsComputed tomography angiography (CTA) is the gold standard for the diagnosis of massive (MPE) and submassive pulmonary embolism (SMPE). Ultrasound has not been accepted as a diagnostic tool. We aim to evaluate the pattern of pulmonary Doppler echocardiography in patients with pulmonary embolism (PE).MethodsFrom 2020 to 2022, 30 patients with acute MPE or SMPE confirmed by CTA and normal pulmonary pressures were selected. A control group was created with 30 individuals without PE. All patients had an echocardiography Doppler study of the pulmonary flow with a focus on early systolic notching (ESN), McConnell's (MC) sign, Right ventricular outflow tract velocity time integral (RVOT VTI), segmental thickness variability (STV), right ventricular end‐diastolic diameter (RVEDD), tricuspid regurgitation (TR) gradient, pulmonary artery pressure (PAP), and acceleration (AT) or ejection time (ET).ResultsESN was identified in 96.6% of PE patients and 0% of the control group (p < 0.001). In comparison with the control group, STV (p < 0.001), RVOT VTI (p < 0.001), ET (p = 0.04), and AT (p < 0.001) values were lower in patients with PE while RVEDD, TR gradient, PAP, ESN, MC sign, and
d‐shape were higher (p < 0.001). Identification of the ESN pattern and AT/ET < 0.4 showed excellent predictive ability for MPE and SMPE with a sensitivity of 97.0% and 100%, specificity of 99.0% and 97%, and an area under the ROC curve of 0.967 (95% CI 0.914−1.00) and 0.933 (95% CI 0.844−1.00), respectively.ConclusionDoppler echocardiography with particular attention to ESN, may be a suitable noninvasive method for the diagnosis of MPE and SMPE. Further studies with more sample sizes are needed to confirm its diagnostic benefit.
Thermo‐mechanical analysis of tumor‐tissue during cryosurgery: A numerical study
Authors: Krishna G. Sai , Paul Anup 
Published: May 2023

AbstractFor decades, many techniques have been developed for curing cancer. Cryosurgery is one of such processes for destroying tumors by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. Presently, this technique is used only for curing simple tumors. Hence, this work aims to trigger this technique toward curing large‐sized internal tumors. The main objectives of this work are (1) to identify the mechanical and thermal behavior of the tumor tissue by conducting a parametric study, (2) to analyze the pain sensation during this process and (3) to identify the constraints of this surgery technique. The whole study was done using COMSOL Multiphysics™ software. A 3‐D model has been presented, considering all the properties to be a function of temperature. Also, the phase transformation bio‐liquid to ice was considered in the study. Results showed the temperature and stress distributions in both tumors and surrounding healthy tissue under different operating conditions. Heat transfer and thermal‐stress in the tissue increased with increase in probe diameter and decrease in tumor size and reached a steady state at around 50 min. The results gave an idea about the time of operation, pain experience and the effect of cryosurgery on the surrounding healthy tissue. Treatment becomes simpler as the tumor moves out of the tissue. The threshold treatment period was predicted to be 50 min, after which patients could expect to experience severe pain. This study might help researchers and surgeons in improving the understanding of cryosurgery process along with its limitations.