bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Various Regimens of Antithrombotic Therapy in Patients With Valvular Heart Disease and Coronary Artery Disease After Surgical and Interventional Interventions
Authors: Ruzina E. V. , Berdibekov B. Sh. , Bulaeva N. I. , Kubova M. Ch. , Golukhova E. Z. 
Published: August 2023

Aim. To evaluate the postoperative incidence of bleeding, incidence of thromboembolic complications, and all-cause mortality in patients with valvular heart disease and ischemic heart disease (IHD) associated with various regimens of the antithrombotic treatment during one year after surgery.Material and methods. This study included 271 patients with valvular heart disease and IHD after heart valve replacement and myocardial revascularization from 2009 through 2018. However, during the follow-up period (12 months), contact with 12 patients was lost, and therefore these patients were excluded from the study. Further analysis included 259 patients. Coronary artery bypass grafting (CABG) in combination with heart valve intervention was performed in 217 (83.8 %) patients, and percutaneous coronary interventions (PCIs) were performed in 42 (16.2 %) patients. There were 197 (72.7 %) male participants; median age was 64.0 [58.0; 67.5] years. The patients were divided into two groups. Group 1 consisted of 113 patients who received postoperative dual antithrombotic therapy (DAT) with acetylsalicylic acid (ASA)/clopidogrel+vitamin K antagonist (VKA). Group 2 included 146 patients receiving postoperative triple antithrombotic therapy (TAT) with ASA+clopidogrel+VKA. Follow-up duration was 12 months after surgery. Due to significant intergroup differences in major clinical anamnestic data, the data were adjusted using pseudo-randomization (Propensity Score Matching, PSM). In result, 109 patients were selected for each group.Results. The incidence of adverse hemorrhagic outcomes was significantly higher in the group treated with TAT than with DAT. Minor bleedings were observed in 19 (17.4 %) vs. 8 (7.3 %) cases; moderate, clinically significant bleedings in 16 (14.7 %) vs. 6 (5.5 %) cases; and the total number of bleedings was 35 (32.1 %) vs. 14 (12.8 %; p=0.02, p=0.02, and р=0.001, respectively). Comparing the incidence of major bleedings did not show and significant intergroup differences (p=1.000). The incidence rate of any bleeding during the follow-up period was 32.1 % in patients treated with TAT (n=109) and 12.8 % in patients treated with DAT (n=109; p=0.005). The incidence of no bleeding during one year after surgery was 87 % in the DAT treatment group and 67 % in the TAT treatment group (p=0.005). The incidence of secondary endpoints, including ischemic stroke, myocardial infarction, prosthetic valve thrombosis, and death, was statistically non-significant.Conclusion. Administration of DAT vs. TAT after heart valve replacement and myocardial revascularization significantly decreases the incidence of any bleedings in the absence of significant differences in the incidence of thromboembolic events and mortality.
Effects of coronary artery calcified plaque and stent on severity and survival of COVID-19 patients: a decision tree model study
Authors: Akman Burcu , Kaya Ahmet Turan 
Published: August 2023

Aim. We aimed to investigate the relationship between the presence of calcified plaques and stents in coronary arteries as evaluated by the chest computed tomography severity score (CT-SS) and mortality rates in patients with COVID-19.Material and methods. A single-center retrospective analysis was conducted of 492 patients (≥18 yrs) who were hospitalized between March and June 2020. All included patients had RT-PCR tests positive for COVID-19. A radiologist recorded pulmonary imaging findings and the presence of coronary calcified plaque and / or stent, sternotomy wires, and cardiac valve replacement on initial non-contrast chest CT. Also, cardiothoracic ratios (CTR) were calculated on chest CTs. Data were analyzed using univariate and multivariate analyses and a chi-squared automatic interaction detection (CHAID) tree analysis, which was developed as a predictive model for survival of COVID-19 patients according to chest CT findings.Results. The mean CT-SS value of the patients with coronary plaque was 11.88±7.88, and a significant relationship was found between CT-SS with coronary calcified plaque (p<0.001). No statistical difference was found between CT-SS and coronary stent (p=0.296). In multivariate analysis, older age was associated with 1.69‑fold (p< 0.001), the presence of coronary calcified plaque 1.943‑fold (p=0.034) and higher CT-SS 1.038‑fold (p=0.042) higher risk of mortality. In the CHAID tree analysis, the highest mortality rate was seen in patients with coronary plaque and CTR>0.57.Conclusion. The presence of coronary artery calcified plaque and cardiomegaly were high risks for severe prognosis and mortality in COVID-19 patients and may help to predict the survival of patients.
Liver fibrosis scores and coronary artery ectasia
Authors: Aydın Cihan , Emlek Nadir , Ergül Elif 
Published: August 2023

Background. Although scoring systems showing liver fibrosis using non-invasive methods have been accepted as effective tools for predicting cardiovascular risk, their role in predicting coronary ectasia (CAE) has not been evaluated. This study investigated whether aprison (APRI) and fibrosis-4 indices (FIB-4), which are indicators of fibrosis in nonalcoholic fatty liver disease (NAFLD), are associated with CAE.Material and methods. A retrospective, cross-sectional study consisted of 215 patients, 108 with CAE and 107 without CAE, as diagnosed by angiography. The mean age of all patients was 61.8±9.9 yrs, and 171 (78.8 %) were males. The relationships between APRI, FIB-4, NAFLD, and Bard scores and CAE were evaluated.Results. APRI, FIB-4, NAFLD, and Bard scores were independent predictors of CAE. Fib 4, APRI, NAFLD, and Bard scores were higher in the CAE patients. There were a moderate, positive correlations for FIB-4, APRI, and NAFLD scores with coronary ectasia (r=0.55, p<0.001; r=0.52, p<0.001; r=0.51, p<0.001, respectively). A weak-moderate positive correlation was observed between the Bard score and CAE (r=0.34, p<0.001). Univariate and multivariate regression analysis showed that APRI score, low HDL, and Bard score were independent risk factors for CAE ectasia (p<0.001). Cut-off values to predict CAE as determined by ROC curve analysis were: FIB-4 index ≥1.43 (AUC=0.817, 95 % confidence interval (CI): 0.762 to 0.873, p<0.001), APRI index ≥0.25 (AUC=0.804, 95 % CI: 0.745 to 0.862, p<0.001), NAFLD score ≥–0.92 (AUC=0.798, 95 % CI: 0.738 to 0.857.p<0.001), Bard score ≥2 (AUC=0.691, 95 % CI: 0.621 to 0.761, p<0.001).Conclusion. APRI, FIB-4, NAFLD, and Bard scores are associated with CAE.
Immune checkpoint inhibitors related cardiovascular toxicity: 3‑mounth follow-up
Authors: Kushnareva E. A. , Gavriluk N. D. , Shuginova T. N. , Urumova E. L. , Karelkina E. V. , Simakova M. A. , Moiseenko F. V. , Moiseeva O. M. 
Published: August 2023

Aim. To analyze the condition of the cardiovascular system in oncological patients receiving immune antitumor therapy with immune checkpoint inhibitors (CPIs) based on results of laboratory and instrumental examinations during a 3-month follow-up.Material and methods. This multicenter prospective observational study included 49 patients (25 men and 24 women aged 65.6±8.7 and 64.3±9.6 years, respectively). A laboratory screening (C-reactive proteins, troponin I, N-terminal pro-brain natriuretic peptide), EchoCG, and carotid ultrasound were performed for all patients. 27 patients were followed up at 3 months after the antitumor therapy initiation. Statistical analysis was performed with the StatPlus 8.0.3 software.Results. Incidence of cardiovascular complications was 16.3 %. The following significant changes in EchoCG parameters were observed: LV EF; (p=0.017), increased LV end-systolic volume (ESV) (р=0.023), and increased LV index of myocardial performance (LIMP; р=0.016). The degree of changes in ESV (ΔESV) depended on a history of chronic heart failure (р=0.03), whereas the degree of changes in EF (ΔEF) depended on the patient’s age at the initiation of antitumor therapy (р=0.006). Ultrasound showed an increase in maximum carotid stenosis (р=0.018).Conclusion. The study showed a high incidence of newly developed cardiovascular complications associated with the CPI treatment as well as the presence of changes in EchoCG parameters and data of carotid ultrasound.
Perubahan pola mobilitas orang pada kawasan peri urban-urban pada masa pandemi: studi spasial pada wilayah Malang Raya
Authors: Aini Nurul , Cahyani Septi Dwi , Setyawan Pungky Eka 
Published: August 2023

<span lang="EN-US">Kebijakan Pemberlakuan Pembatasan Kegiatan Masyarakat (PPKM) pada masa Pandemi Covid-19 berdampak terhadap kegiatan di berbagai sector yang mempengaruhi pergerakan masyarakat kawasan periurban ke kawasan urban untuk berbagai tujuan. Penelitian ini bertujuan menganalisis perubahan pola pergerakan masyarakat tersebut dengan menggunakan analisis deskriptif statistik. Data dikumpulkan melalui kuesioner dan dianalisis dengan matriks asal-tujuan untuk melihat perubahan pola dan karakteristik pergerakan sebelum dan saat pandemic berlangsung. Perubahan pola dan karakteristik perjalanan selanjutnya dianalisis dengan perspektif spasial berbasis GIS. Hasil penelitian menunjukkan adanya perubahan pola pergerakan pada 38% masyarakat. Perubahan terbesar terjadi pada motif pergerakan bersekolah ke kawasan urban. Hasil dari penelitian diharapkan bisa berkontribusi sebagai salah satu dasar pertimbangan dalam merencanakan kebijakan, baik dalam aspek spasial, pembangunan fisik perkotaan serta perekonomian ketika menghadapi kembali sebuah pandemi.</span>
Production Profiles Recorded Using Fiber-Optic Technology in Wells with Electrical Submersible Pump Lift System
Authors: Ramirez Palacio Gabriel Jaime , Almario Felipe , Castro Chacon Alexander , Meza Rojas Eliana , Hernandez Nini Johana , Valencia Maria 
Published: August 2023

SummaryFiber-optic distributed sensor technology has rapidly evolved over the past 30 years, becoming very useful in the hydrocarbon sector for different operations, such as pipeline leak monitoring, production and injection logging, fracture monitoring, vertical seismic profiling, and steam injection, among others. Monitoring temperature is a critical aspect of reservoir development and a well’s life cycle, given its broad range of applications. Temperature profiling is commonly used in production logging, often in conjunction with other sensors to quantify and identify fluids. This paper discusses two prevalent scenarios encountered in the Llanos Orientales region of Colombia, where 28 wells with electrical submersible pump (ESP) lifting systems were impacted. During the execution of these fiber-optic logs, two conditions of particular interest were explored: wells with low-flow rates below 500 barrels per day and wells with mechanical limitations that preclude monitoring with conventional sensors due to the presence of stainless-steel bands at the bottom of the well. The fiber-optic string provided access to the drilling zone, enabling temperature and pressure monitoring of the production intervals. To interpret the data, a probabilistic model based on enthalpy balance, mass, and conservation of momentum was used to determine the well’s production profile.
UV and IR divergence-free calculation of the vertex function at arbitrary values of its arguments
Authors: Mashford John 
Published: August 2023

Abstract
The mathematics of covariant spectral regularization for covariant matrix valued measures with one Lorentz index on open subsets of Minkowski space is described. This is then applied to the case of the vertex function and expressions for the densities associated with the vertex function in the t channel and the s channel with respect to Lebesgue measure on Minkowski space are obtained. These densities are well defined, non-divergent and analytic over their domains of definition and are obtained without using renormalization or needing to consider final state radiation. The limit of the expression for the vertex function in the t channel at low energy and low momenta is computed resulting in the classical result for the leading order (LO) contribution to the anomalous magnetic moment of the electron. Also the density for the vertex function in the s channel is used to compute the NLO vertex correction contribution to the high energy limit of the cross section for the process e+ e−→µ + µ−.
Self-filtering Low Noise Horn Antenna Using Bi-omega Particle
Authors: KVBL DEEPTHI , CH Sravani , M Sreelekha , K Sruthi 
Published: August 2023

Abstract
A unique self-filtering low-noise horn antenna is presented in this research. The purpose of this design is to lower the WR-62 horn antenna's operating bandwidth so that it can self-filter the noise it picks up while operating. A broadband radiator is a horn antenna. In the microwave frequency range of 30 to 40 GHz, known as the ka band, the proposed design is simulated. As a result, the high-frequency band experiences good return losses. The right supplementary components, such as biomega particles that are often employed as the filter, are normally required to limit the noise captured by the antenna, which typically affects the performances in the receiving mode. Comparing the basic WR-62 horn antenna's bandwidth with and without biomega particles. Additionally, comparisons are drawn between single and double slits. The effectiveness of the suggested design, which can be successfully used in receiving satellite communication systems, has been verified by a proper set of numerical simulations and experiments.
Stable Blue Quantum Dot LED with 23% external quantum efficiency
Authors: Zhang Wenjing , Li Bo , Chang Chun , Chen Fei , Zhang Qin , Lin Qingli , Wang Lei , Yan Jinhang , Wang Fangfang , Chong Yihua , Du Zuliang , Fan Fengjia , Shen Huaibin 
Published: August 2023

Abstract
The efficiency and stability of red and green quantum dot light-emitting diodes (QD-LEDs) have already met the requirements for displays. However, the performances of blue QD-LEDs, particularly pure blue QD-LEDs, are far inferior to that of their counterparts, hindering the commercialization of full-color QD-LED technology. Severe electron and hole accumulation at the hole transport layer (HTL) and quantum dot (QD) interface are the causes of efficiency loss and poor stability. Here, we propose inserting a protective layer (PBO (Poly-p-phenylene benzobisoxazole)) between the HTL and QD layer to suppress the accumulation of electrons and holes at the HTL/QD interface, reducing electron leakage and alleviating the damage to the HTL. This strategy enables us to achieve a record peak external quantum efficiency (EQE) of up to 23% and a record T50 operational lifetime of more than 41000 h with an initial brightness of 100 cd m-2 in pure blue QD-LEDs (emitting at 458 nm). The mitigated electron and hole accumulation at the HTL/QD interface is confirmed by capacitance-voltage characteristics and electro-absorption spectra.
The investigation of SNP in SOCS2 gene associated with mastitis resistance, milk composition, and quality in Awassi sheep.
Authors: hasan mubeen Ul , Ceyhan Ayhan 
Published: August 2023

Abstract
Background

Mastitis is commonly known as udder infection in dairy animals which in severe cases can cause death in livestock. Farmers face financial losses yearly because milk yield and components such as milk fat are reduced due to mastitis incidence. The milk products obtained from sheep milk all over the world rely on its high-fat content and increased milk yield. However, the incidence of clinical mastitis is a reason for increased somatic cell count. The milk fat content and yield are severely affected by the increased somatic cell count. Our study aimed to investigate the presence of a particular SNP rs868996547, which is related to milk somatic cell count, fat, and yield.

Methods

In this study, lactation data obtained from 210 healthy Awassi ewes were used. The milk content data, fat, protein, lactose, milk solids, and somatic cell count were collected. The DNA extraction was done by using a blood DNA extraction kit from Qiagen. To validate the presence of SNP we sent our SNP id number to Thermofisher Scientific for designing a custom SNP detection Assay.

Conclusion

Our results showed that SNP was present in some Awassi ewes while it was absent in others. The study results showed that there was a significant association between the SNP presence and SCC and milk fat content and milk yield.
Subclinical low vitamin D related to systemic sclerosis and resistant to long-term oral supplementation rapidly improves after two intramuscular injections of ergocalciferol: a retrospective observational case series.
Authors: Mallat Farid , Aoun Maroun , Jabbour Rita , Hachem Samir , Soutou Boutros , Helou Josiane 
Published: August 2023

Abstract
Background
Low vitamin D level is common in patients with systemic sclerosis since synthesis comprises cutaneous, gastrointestinal, hepatic, and renal steps. Oral supplementation brought less than a third of patients to a normal level. No study has yet reported effective alternatives.
Aims
The objective was to assess the response to intramuscular vitamin D in patients not responding to oral supplementation.
Methods
A retrospective series included patients, with systemic sclerosis and a history of subclinical poor vitamin D status that was resistant to at least 6 months of oral supplementation, to whom intramuscular vitamin D2 was administered. File data were collected for disease characteristics, vitamin D2 posology, and 25(OH)D serum levels.
Results
Twelve patients were identified, with a mean age of 51.9 years. All were women. Five had diffuse systemic sclerosisand seven had localized systemic sclerosis. The mean duration of the disease was 17.9 years, with a mean modified Rodnan skin score of 14. All patients were twice injected, at a 15-day interval, 300,000 IU of ergocalciferol into the anterior gluteus muscle. The mean serum level of 25(OH)D increased from 12.9 ng/mL before the first injection, to 23 ng/mL two weeks after the first injection, and 37.1 ng/mL four weeks after the second injection. No side effects were observed.
Conclusions
It is the first report of safely normalizing vitamin D levels with intramuscular ergocalciferol in patients with a connective tissue disease and a low vitamin D level refractory to oral supplementation.
Visual Field Progression Patterns in the Ocular Hypertension Treatment Study Correspond to Vulnerability Regions of the Disc
Authors: Leshno Ari , Bommakanti Nikhil , De Moraes Carlos Gustavo , Gordon Mae , Kass Michael , Cioffi George , Liebmann Jeffrey 
Published: August 2023

Abstract
Objectives

To determine the locations on the 24-2 visual field (VF) testing grid that are most likely to progress in patients with ocular hypertension (OHTN). Based on a structural model of superior and inferior areas of relative vulnerability at the optic disc, we hypothesized that the nasal and paracentral regions are more prone to show a reduction in sensitivity.

Methods

This is a posthoc analysis of the data from a randomized controlled clinical trial. Data collected from patients enrolled in the Ocular Hypertension Treatment Study (OHTS) Phases 1 and 2 were used. A pointwise analysis was applied to determine the progression patterns in the early and delayed treatment groups. Each group's progression rate and frequency were calculated for each of the 52 locations corresponding to the 24-2 VF strategy, using trend- and event-based analyses, respectively.

Results

For the event-based analysis, the events were most commonly found in the nasal and paracentral regions. The same regions, with some modest variation, were found to have the fastest rates of progression (ROP) measured with trend analysis. A similar pattern of progression was observed in both the early and delayed treatment groups.

Conclusions

Development of VF loss in ocular hypertensive eyes is consistent with the vulnerability zones previously described in glaucomatous eyes with established VF loss. This suggests that these locations need to be most carefully monitored.
CILPA: An Overlapping Community Detection Algorithm Based on Label Propagation and Node Information
Authors: Liu Hongtao , Shen Yanxiu 
Published: August 2023

Abstract

With the proliferation of complex networks, a large number of effective community detection methods have been developed. Of these, the label propagation-based approach for community detection has proven to be very suitable for community detection. However, it should be noted that this approach is stochastic and unstable. To address these issues, a CILPA method is proposed based on label Propagation and node information to identify a more rational community. First, we obtain the local influence reflecting the local spatial location of nodes based on their neighbourhood relationships. The importance of the nodes is subsequently obtained by combining topological information and local influence. Secondly, a label propagation strategy with preference selection is introduced to obtain stable overlapping communities based on neighbourhood information. More importantly, a label checking strategy is articulated to reduce the impact of sparse connections. Extensive experiments on the LFR benchmark network and real-world networks demonstrate that the approach is both stable and effective.
Economic and Psychosocial Impact of Covid-19 Vaccine non-compliance amongst Australian Healthcare Workers.
Authors: McDonald Charles I , Parry Peter , Rhodes Peter 
Published: August 2023

Abstract

Background In September 2021 public health employees in the state of Queensland, Australia, were directed to accept Covid-19 vaccination, or risk disciplinary procedures, suspension and termination of employment. We hypothesised those non-compliant with this mandate would suffer economic hardship, psychosocial harm and possible suicide risk. Wider ramifications might include loss of highly skilled personnel from the workforce. Methods In early 2023 an online survey was disseminated through social media. This consisted of 63 questions on employment; exemptions; natural immunity; disciplinary action; appeals; economic and psychosocial harms. Results Of 369 participants, the majority were female (85.9%) and of nursing profession (55%). We found a reduction in income (reported by 94.4%). The majority (94.9%) believed psychosocial harm was caused as a direct result of state government policy. Anxiety and depression were experienced by 92.1% while 34.1% had had thoughts of suicide. Conclusion This survey of staff disciplined for non- compliance with Covid-19 vaccine mandates in the state of Queensland, Australia, found significant harm. Impact was biased against females and single parent households. Natural immunity was dismissed by authorities. The disciplinary processes failed to consider economic or psychological damage. The devastation caused could have intergenerational impact beyond that revealed in this study.