bluuebunny/crossref_metadata_2025_split huggingface dataset:
Value of focused assessment with sonography for trauma in management of hypotensive polytrauma patients– A Meta-analysis
Authors: Awad Philobater , Hassan Basma 
Published: January 2023

Abstract
Background
Severe or major trauma is a worldwide pandemic and one of the leading causes of death and disability. Polytrauma always involves young, productive individuals and represents a substantial burden on the society Management of Trauma injuries generally emphasizes the importance of identifying and prioritizing the most serious life-threatening injuries and managing them. Management consists of a rapid primary survey, resuscitation of vital functions, a more detailed secondary survey, and, finally, the initiation of definitive care. Damage-control surgery has increasing role as it proves reliability in the most sensitive situations.
Objective
To assess the Value of focused assessment with sonography for management of hypotensive polytrauma patients.
Patients and Methods:
All trials about the usage include participants who came to ER due to polytrauma with blunt or penetrating abdominal trauma or with undifferentiated shock, randomized controlled trials and prospective or retrospective cohort studies that assess the value of focused sonography in hypotensive polytrauma patients.
Results
The value of an odds ratio like that of other measures of test performance for example sensitivity and specificity and likelihood ratios depends on prevelance. For example, a test with pooled diagnostic odds ratio of 10.00 is considered to be very good by current standards, therefore pooled diagnostic odds ratio of 77.46 which is considered to be very good. Spearman correlation coefficient:-0.429 with p value 0.397 which is insignificant so, there was low threshold effect Positive and negative Likelihood ratio both are done on six studies with positive likelihood ratio is 21.27 and negative likelihood ratio is 0.29 sensitivity and specificity are done on the six studies with pooled sensitivity is 0.73 and pooled specificity is 0.98.
Data Sources:
Medline databases (PubMed, Medscape, ScienceDirect. EMF-Portal) and all materials available in the Internet till 2022.
Conclusion
FAST is significant in polytrauma patients especially in hypotensive patients with considerable accuracy rate 77.46 and good pooled sensitivity with 0.73 and pooled specificity with 0.98 and good ROC curve with are under the curve 0.70.
Attentional Ptycho-Tomography (APT) for three-dimensional nanoscale X-ray imaging with minimal data acquisition and computation time
Authors: Kang Iksung , Wu Ziling , Jiang Yi , Yao Yudong , Deng Junjing , Klug Jeffrey , Vogt Stefan , Barbastathis George 
Published: January 2023

Abstract
Noninvasive X-ray imaging of nanoscale three-dimensional objects, such as integrated circuits (ICs), generally requires two types of scanning: ptychographic, which is translational and returns estimates of the complex electromagnetic field through the IC; combined with a tomographic scan, which collects these complex field projections from multiple angles. Here, we present Attentional Ptycho-Tomography (APT), an approach to drastically reduce the amount of angular scanning, and thus the total acquisition time. APT is machine learning-based, utilizing axial self-Attention for Ptycho-Tomographic reconstruction. APT is trained to obtain accurate reconstructions of the ICs, despite the incompleteness of the measurements. The training process includes regularizing priors in the form of typical patterns found in IC interiors, and the physics of X-ray propagation through the IC. We show that APT with ×12 reduced angles achieves fidelity comparable to the gold standard Simultaneous Algebraic Reconstruction Technique (SART) with the original set of angles. When using the same set of reduced angles, then APT also outperforms Filtered Back Projection (FBP), Simultaneous Iterative Reconstruction Technique (SIRT), and SART. The time needed to compute the reconstruction is also reduced, because the trained neural network is a forward operation, unlike the iterative nature of these alternatives. Our experiments show that, without loss in quality, for a 4.48×93.2×3.92 μm3 IC (≈ 6×108 voxels), APT reduces the total data acquisition and computation time from 67.96 hours to 38 minutes. We expect our physics-assisted and attention-utilizing machine learning framework to be applicable to other branches of nanoscale imaging, such as material science for crystal defects, biological imaging for viruses, etc.
Homology Modeling of Carbonic Anhydrase from Dunaliella Viridis
Authors: azimuddin syed muhammad iqbal 
Published: January 2023

Abstract

Under salt and toxic metal stress condition, genetic make-up and proteins including some enzymes undergo specific changes to combat the posed harsh environment. Carbonic anhydrase is ubiquitous enzyme associated with respiratory disorder and cancerous condition. Strategies investigated and adopted by microorganisms to cope with hypersaline by bioinformatics analysis including homology modeling, Zinc metal interaction prediction, sequence analysis for Carbonic Anhydrase. This study shows that carbonic anhydrase acquired more acidic residues on its surface as countermeasure and may form salt bridges with positive ions in response to hypersaline environment. It also reduced its surface area and had more polar residues. Zinc metal interaction with Nitrogen of Histidine residues were almost conserved in the studied and modelled structure with fewer changes in catalytic region of sequence pattern. Salt tolerance achieved by foster promising approaches at the genetic and proteomic level by modifying protein sequence. Surface residues are exposed to a hypersaline medium and are mainly composed of polar and acidic residues. The enzyme exists in its compact form and reduces its surface footprint exposed to outside environment. Beta pleated secondary structure configuration increases flexibility to counter, ions disruptive effect.
WITHDRAWN: Global multi-omics profiling reveals evolutionary drivers of phylogeographic diversity of fungal specialized metabolism
Authors: Xie Huali , Hu Jie , Yue Xiaofeng , Zhao Fang , Chen Jianwei , Hooft Justin J.J. van der , Medema Marnix , Li Peiwu , Zhang Qi 
Published: January 2023

Abstract

Chemical innovation is essential for fungi to adapt to specific geographical environments and ecological niches. However, it remains unclear how genomic changes drive fungal specialized metabolic differentiation across the biosphere. Here, we studied the global genomic and metabolic diversity of the aflatoxin-producing Aspergillus flavus as a case. We generated paired genome and metabolome data for > 550 strains from across China, and supplemented this with 187 publicly available genomes from other countries. We found that the global genetic diversity of A. flavus shows strong phylogeographic patterns, with specific clades associating with different environments. These clades exhibit distinct specialized metabolic profiles, with low-aflatoxin-producing clades often producing other mycotoxins instead. Furthermore, clade-specific gene clusters do exist that could be linked to clade-specific metabolites, implying that different niches select for the production of different toxins. Our results reveal that these different mycotoxin profiles are generally not explained by loss or gain of biosynthetic gene clusters, but are likely driven by regulatory and primary metabolic variation. Altogether, our findings provide a framework to understand fungal environmental adaptation and pave the path towards enhanced mycotoxin early risk prediction and ‘personalized’ geographical control strategies.
Comparative efficacy of S-shaped partial nail fold resection combined with lateral groove reconstruction and matrix phenolization on onychocryptosis: a retrospective study
Authors: Liu Juan , Zhou Yuan , Liu Meng-xi , Liu Zhen-ru , Wang Xiao-qing , Li Fang , Wang Da-guang 
Published: January 2023

Abstract
Background: Onychocryptosis is a pathologic condition and accounts for many clinical consultations. Selection for a suitable and effective treatment is crucial according to patients’ particular situation. To compare the efficacy and safety of S-shaped partial nail fold resection combined with lateral groove reconstruction versus matrix phenolization in patients with onychocryptosis.
Methods: A total of 107 onychocryptosis participants at stage IIb and III were divided into 2 groups: 75 nails of 73 patients were treated with S-shaped partial nail fold resection combined with lateral groove reconstruction (S-shaped group) and 42 nails of 34 patients were treated with matrix phenolization (Phenol group). Clinical cure rate and post-surgery complications were evaluated. Besides, the new procedure was performed in 31 nails of 29 participants at stage IV in order to evaluate its efficacy.
Results: After 6 months, in the remain 102 patients (110 nails), there was no statistically significant difference in clinical cure and satisfaction between two groups (P = 0.62 and 0.506, respectively). Fewer patients showed complications, including narrowed nail width and onycholysis, in the S-shaped group than the Phenol group (5.88 % vs. 45.2 %, P < 0.001). Besides, shorter healing time was observed in S-shape group (13.5 ± 1.4 vs 27.6 ± 2.3 days, P < 0.001). Postoperative pain was obvious in the S-shape group at the first postoperative day (P < 0.001), while a clear decrease in pain score was observed at 2 weeks after surgery (P = 0.407). Moreover, this nail-sparing surgery was successful used in stage IV patients with 100% cure rate.
Conclusion: The new surgery has both benefits and drawbacks. The advantages are normal width nail plate and short healing time. The drawbacks are severe postoperative pain and complicated in operation. Therefore, matrix phenolization is recommended to cases at stage IIb and III, our new surgery is recommended to those patients with high demands of esthetic. Additionally, our new surgery is suitable to stage IV patients, with hypertrophic tissue completely covers lateral, medial, and distal nail plate.
Odontogenic factors that affect the maxillary sinus Schneiderian membrane and their relationship to chronic sinonasal symptoms
Authors:   Maha Alghofaily1, Alsufyani Noura , Althumairy Riyadh , AlSuhaibani Amal , Alfawzan Fatimah , AlSadhan Lama 
Published: January 2023

Abstract

Background:Odontogenic sinusitis is a common maxillary sinus disease. It develops due to the violation of the Schneiderian membrane due to pathological, iatrogenic, or traumatic causes from dental and dentoalveolar structures. This study aimed to investigate local and systemic factors associated with Schneiderian mucosal thickening (MT) in patients referred for post-endodontic diseases and their relationship with chronic sinonasal symptoms.Methods:A retrospective evaluation of cone-beam computed tomography (CBCT) scans of patients referred for evaluation of post-endodontic diseases was performed. Mucosal thickening in relation to the affected tooth was measured in the coronal section in millimeters at the maximum area perpendicular to the bone. Based on this measurement, the sinus floor was categorized for MT as present (>1 mm) or absent (<1 mm). The sociodemographic and clinical characteristics of the study participants were assessed and compared according to the presence or absence of MT. Furthermore, the relationship between odontogenic sinusitis and chronic sinonasal symptoms was assessed using a Chronic Sinusitis Survey.Results:Male patients had a higher MT than female patients. The presence of periapical lesions and inadequate endodontic treatment were significantly associated with MT. The multivariate logistic regression model showed that the presence of PA lesions increased the odds of MT by approximately 2.5 times (p = 0.028), and nasal obstruction was significantly higher in patients diagnosed with mucosal thickness at different time of follow-ups period (p = 0.018).Conclusions: MT was 2.4 times more likely in the presence of periapical pathosis, and nasal obstruction was the most significant factor associated with the presence of MT.
Polarization Property of 3D-Crosslinked Polymer at Variation axis of Transmitted Light
Authors: Tukimin Siti Nurainie , Karman Salmah Binti , Zaman Wan Safwani Wan Kamarul , Nordin Fazlina , Ahmad Mohd Yazed 
Published: January 2023

Abstract
Classification of biomaterial using polarization of light at present having difficulty for label-free and direct optical detection. The optical properties of a sample which are profoundly explored through the absorption coefficient, scattering coefficient, anisotropy coefficient and degree of linear polarization (DoLP) are neither simple nor easy to handle. In this study, Angle of polarized light (AOP) is our biggest concern. Neither need labeling procedure nor hardly to measure. Instead of linear polarization, this study determined the angle of polarized light as a potent parameter for polarization measurement at the variation axis of transmitted polarized light. Hence, this work was mainly conducted to identify the angle of polarized light for classification of agarose sample, a three-dimensional crosslinked polymer. In this work, a photodiode acts as a polarized light sensor to read voltage changes due to variable concentrations of agarose samples. At the end of the study, relationships between the Angle of Polarized light (AOP) and concentrations of agarose sample at variation axis of transmitted light were successfully investigated. Our result demonstrated a linear correlation between measured voltage (mV) and the concentration of agarose sample (g/ml) with output polarization behavioral model (AOP, ϴ◦) at variation axis of transmitted light. This outcome concluded that the polarization property of the agarose sample in perspective of angle can be identified at variation axis of transmitted light. Therefore, our polarization measurement-setup with variation axis of light transmission is reliable to determine the polarization property of the unknown three-dimensional structure of tissue-mimicking phantom in the future.
WITHDRAWN: Peace, Conflicts, and the Covid-19: A Meta-Analysis at Global Level
Authors: Azadi Hossein , Ghazali Samane , Pour Mahdad 
Published: January 2023

Abstract

Background: The Covid-19 may be a great opportunity for humane solidarity to decrease the prevalence of disease, but it could also be a threat to protests due to the deteriorating economic situation. Hence, the objective of this research was to determine the peaceful and violent effects of the Covid-19 outbreak worldwide. The expansion ofCovid-19 can have various peaceful and violent effects in terms of solidarity, collapse of tourism, and internal and foreign conflicts.
Methods: In the current study, a meta-analysis was performed to synthesize the results of 34 original studies published for the last year (from January 2020 to April 2021).
Results: The findings showed that the outbreak of the Covid-19 would lead to greater solidarity and more collapse of tourism. The meta-regression findings showed that spread of the Covid-19 significantly affects internal and foreign conflicts even through recession and unemployment. However, there is no considerable impact of the Covid-19 on internal and foreign conflicts considering health status. In terms of the spatiotemporal impacts of spread of the Covid-19, the collapse of tourism has the greatest temporal effect, and European countries show the most spatial effects.
Conclusions: Therefore, this study recommends economic decision-makers to financially support social groups working together against the Covid-19. In addition, decision-makers in the field of health must consider that services in the tourism sector should be provided by observing health protocols such as low passenger capacity, use of hygienic materials and disinfectants, and compliance with social distance.
On index divisors and monogenity of certain number fields defined by x12+axm+b
Authors: Fadil Lhoussain El , Kchit Omar 
Published: January 2023

Abstract
In this paper, we study the monogenity of any number field defined by a monic irreducible trinomial F(x) = x12 + axm + b ∈ Z[x] with 1 ≤ m ≤ 11 {an integer. For every integer m, we give sufficient conditions on a and b so that the field index i(K) is not trivial. In particular, if i(K) ≠ 1, then K is not monogenic. For m=1, we give necessary and sufficient conditions on a and b, which characterize when a rational prime p divides the index i(K). For every prime divisor p of i(K), we also calculate the highest power p dividing i(K), in such a way we answer the problem 22 of Narkiewicz [20] for the number fields defined by trinomials x12+ax+b.
2010 Mathematics Subject Classification. 11R04, 11Y40, 11R21.
The systemic immune-inflammation index is associated with Type 2 diabetes mellitus patients: Evidence from NHANES 2011-2018
Authors: Liu Pengyu , Shang Juju , Luo Danqing , Shi Lixiao 
Published: January 2023

AbstractBackgrounds The Systemic Immune-Inflammation Index (SII), as a novel inflammatory biomarker, has not been researched for type 2 diabetes mellitus (T2DM). This study was designed to investigate the potential association between SII and T2DM. Methods This cross-sectional study focused on adults enrolled in 2011 and 2018 by National Health and Nutrition Examination Survey (NHANES). Univariate, as well as multivariate logistic regression analyses, subgroup analyses, and sensitivity analyses, were performed to determine the independent association between SII and T2DM. The relationship between ln-SII and T2DM was described by the fitted smoothing curve. Results A total of 10,321 subjects were enrolled in the study; of which 2,078 (20.1%) were diagnosed with T2DM. After full adjustment, multivariate logistic regression demonstrated that higher SII was an independent risk factor for increased T2DM (OR = 1.30; 95% CI, 1.08–1.56, p < 0.0001). There was no relevant association of age, race, physical activity, high blood pressure, and smoking status(all p < 0.05), as demonstrated by the subgroup analysis and the interaction study. In addition, the relationship between SII and T2DM is non-linear; as ln-SII increases, the potential for T2DM gradually increases. Conclusions Elevated SII levels were linked to a higher probability of developing T2DM. More large and prospective studies will be required to confirm the results of this study.
Investigation of acidification and changes in mineral element concentrations of Guizhou yellow soils in long-term tea plantations
Authors: Lin Shaoxia , Liu Xiaolan , Yan Qiuxiao , Wei Fuxiao , Wang Daoping 
Published: January 2023

Abstract
This study aimed to investigate where acidification occurred in soil profiles of Guizhou tea gardens, in addition to the influence of acidification on the availability of soil mineral elements in order to inform soil nutrient management and improvement practices in tea gardens. Important tea-producing areas of Guizhou were investigated in this study and samples were collected from tea gardens with similar soil parent material and management measures. The acidification characteristics were investigated in soils from plantations grown for various numbers of years and across different soil layer profiles. Moreover, the pH buffering capacities (pHBC) of soils were evaluated and changes in soil Fe, Mn, Cu, Zn, Mo, B, As, Pb, Cr, and Cd concentrations due to soil acidification were explored. With increased tea plantation age, the acidification rate of 0–20-cm soil layers reached 0.025 pH unit/year. Soil acidification extended from the surface layer downwards through profiles, while the pH of entire soil layers were < 4.5 after 40 years of tea plantation. The pHBC of soils were < 30 mmol/kg, remaining at a weak sensitive level. Fe, Mn, Cu, Zn, Mo, and B concentrations exhibited decreasing trends in soils, while As, Pb, Cr, and Cd exhibited enrichment at the surface. Tea plantation age and soil depth were significantly correlated with the available concentrations of soil mineral elements. Soil acidification gradually increased downward from the surface and soil minerals were lost in acidic environments, while the acid buffering capacity was reduced. These results suggest that organic fertilizers and trace elements should be supplemented as needed in the management of tea gardens to achieve long-term stability of quality and yields.
Diachronic Profile of Startup Companies through Social Media
Authors: Peixoto Ana Rita , de Almeida Ana , António Nuno , Batista Fernando , Ribeiro Ricardo 
Published: January 2023

Abstract

Social media platforms have become powerful tools for startups, helping them find customers and raise funding. Analysing the contents posted through social media would help them make the best use of this communication and scale their business. To understand if a startup’s social media content reflects its position in its business maturation, we start by defining an adequate life cycle model for startups based on two dimensions: funding rounds and product maturity. Using Twitter as social media source of information for known Portuguese IT startups, each at their life cycle’s different phases, their tweets’ data has been analyzed. Topic modeling techniques have enabled the categorization of the data according to the topics arising in the published contents, making it possible to discover that contents can be grouped into five specific topics: “Fintech and ML”, “IT”, “Business Operations”, “Product/Service R&D”, and “Bank and Funding”. Comparing those profiles against the startup’s life cycle to understand how contents change over time provides a diachronic profile for each company. We discovered that while some topics are prevalent in the startup’s scaling, others depend on the startup’s particular phase of the cycle, revealing that startups’ Twitter social media content differs along their life cycle.
Ion induced field screening governs the early performance degradation of perovskite solar cells
Authors: Thiesbrummel Jarla , Shah Sahil , Gutierrez-Partida Emilio , Zu Fengshuo , Camargo Francisco , Zeiske Stefan , Diekmann Jonas , Ye Fangyuan , Peters Karol , Brinkmann Kai , Warby Jonathan , Jeangros Quentin , Lang Felix , Wu Yongzhen , Albrecht Steve , Riedl Thomas , Armin Ardalan , Neher Dieter , Koch Norbert , Corre Vincent , Snaith Henry , Stolterfoht Martin 
Published: January 2023

Abstract
In the last decade, perovskite semiconductors have triggered a revolution in solar cell research. However, critical issues remain concerning the stability of metal-halide perovskites, which need to be overcome to enable a large scale commercialisation of perovskite photovoltaics (PV). While the rather poor environmental stability of these perovskites is usually attributed to their ionic nature rendering them sensitive to moisture and oxygen, the actual contribution of mobile ions to the total degradation loss under different environmental conditions is poorly understood. In this work, we reveal that the initial degradation of perovskite semiconductors is largely the result of mobile ion-induced internal field screening - a phenomenon that has not been previously discussed in relation to the degradation of perovskite solar cells. The increased field screening leads to a decrease in the steady-state power conversion efficiency mainly due to a large reduction in current density, while the efficiency at high scan speeds (>1000 V/s) where the ions are immobilized is much less affected. We also show that interfacial recombination does not increase upon ageing, yet the open-circuit voltage (VOC) decreases as the result of an increase in the mobile ion density upon ageing. Furthermore, similar ionic losses appear under different external stressors, in particular when there are free charges present in the absorber layer. This work reveals a key degradation mechanism, providing new insights into initial device degradation before chemical or extrinsic mechanical device degradation effects manifest, and it highlights the critical role mobile ions play therein.