bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Benefits of Early Mobilization on Post-Abdominal Surgery: A Review of Literature
Authors: Juita Juita , Yona Sri , Maria Riri 
Published: June 2023

Background: post-abdominal surgery and postponed physical recovery are significant problems. Thus, early mobilization is important to treat the post-surgical procedure, facilitate recovery, and prevent further complications.
Objectives: this literature review was to find the benefits of early mobilization on post-abdominal surgery.
Methods: the researchers took the data from PubMed, EBSCOhost, ProQuest, Science Direct, and Scopus, published from 2017-2022 with the predetermined keywords. The searching method applied the Prefered Reporting Items for Systematic Review and Meta-Analysis, PRISMA guideline. The researchers conducted the research in November 2022. Articles selected with criteria for publication in International Journals within the last five years, in English, using experimental research designs, randomized controlled trials (RCTs), quasi-experiments, and cohort studies.
Results: the researchers found 57.990 articles from various data sources. They were Pubmed (n = 43), EBSCOHost (n = 1.223), Science Direct (n = 325.800), ProQuest (n=30.279), and Scopus (n=645). After promoting the first screening step, the researchers eliminated some obtained journal articles. The only articles published within five recent years with full-text conditions were 162 articles. Then, the researchers screened the articles based on the second and third criteria: having open access and writing in English. The results were 10 articles. Then, the researchers checked the duplications and screened the titles and the abstract, resulting in six articles. The results showed that the analyses of six articles stated that early mobilization, from the post of day 0 or 24 hours after the abdominal surgery could improve the respiratory function with SpO2 and SaO2 increase. The mobilization could also reduce the length of stay and make the cost more efficient.
Conclusion: The mobilization provided many advantages to reducing post-abdominal surgery complications, morbidity, and mortality.
Penguatan Nilai-Nilai Ideologi Pancasila dan Nasionalisme Pada Generasi Muda Pedesaan di Desa Betteng Kecamatan Pamboang Kabupaten Majene
Authors: Ibnu Khaldun Riady , Antuli Rezky Ramadhan , Sajidin Muhammad , Winata Verry Candra , Anca Al 
Published: June 2023

Pancasila adalah dasar untuk mewujudkan persatuan dan kesatuan Bangsa Indonesia yang juga sebagai ideologi bangsa memuat cita-cita berdasarkan apa yang telah disusun oleh para pendiri bangsa. Saat ini masih jarang dilaksanakan penguatan Pancasila khusunya di wilayah perdesaan, sehingga pemahaman masyarakat akan nilai-nilai pancasila masih kurang, Pelaksanaan pengabdian kepada masyarakat telah merujuk dari situasi yang terjadi didukung dengan hasil observasi yang bertujuan untuk menanamkan Nilai-Nilai Ideologi Pancasila dan Nasionalisme kepada para young generation atau generasi muda pedesaan di Desa Betteng Kecamatan Pamboang Kabupaten Majene, Pengabdian ini melibatkan dosen dan mahasiswa universitas sulawesi barat, dengan tahapan 1) Persiapan; 2) Koordinasi dengan Pemerintah Desa; 3) Pembekalan mahasiswa; 4) Melaksanakan kegiatan penanaman nilai yang terkandung di dalam Pancasila dan penanaman semangat nasionalisme. Adapun hasil pelaksanaan kegiatan ini adalah mendorong peningkatan pemahaman Nilai-Nilai Pancasila dan sikap nasionalisme yang diaplikasikan dalam kehidupan sehari-hari oleh generasi muda pedesaan di Desa Betteng.
Finite element study of the biomechanical effects on the rotator cuff under load
Authors: Yang Zhengzhong , Xu Guangming , Yang Jiyong , Lin Xiaosheng 
Published: June 2023

Rotator cuff injuries account for 50% of shoulder disorders that can cause shoulder pain and reduced mobility. The occurrence of rotator cuff injury is related to the variation in shoulder load, but the mechanical changes in the rotator cuff caused by load remain unclear. Therefore, the mechanical results of the rotator cuff tissue during glenohumeral abduction and adduction were analyzed based on a finite element shoulder model under non-load (0 kg) and load (7.5 kg) conditions. The results showed that the maximum von Mises stress on the supraspinatus muscle was larger than that on the subscapularis, infraspinatus, and teres minor muscles during glenohumeral abduction. Compared with the non-load condition, the maximum von Mises stress on the supraspinatus muscle increased by 75% under the load condition at 30° abduction. Under the load condition, the supraspinatus joint side exhibited an average stress that was 32% greater than that observed on the bursal side. The von Mises stress on the infraspinatus muscle was higher than that in other rotator cuff tissues during adduction. The stress on the infraspinatus muscle increased by 36% in the load condition compared to the non-load condition at 30° adduction. In summary, the increased load changed the mechanical distribution of rotator cuff tissue and increased the stress differential between the joint aspect and the bursal aspect of the supraspinatus tendon.
Preliminary analysis of nonlinear site response at the S-net seafloor sites during three Mw 7 class earthquakes
Authors: Dhakal Yadab P. , Kunugi Takashi 
Published: June 2023

In this paper, we investigated the characteristics of nonlinear site response (NLSR) at 23 S-net seafloor sites using strong-motion records obtained during three Mw 7 class earthquakes that occurred directly beneath the network. During the earthquakes, horizontal peak accelerations as large values as 1,400 and 1700 cm/s2 were recorded at the land (KiK-net) and S-net stations, respectively. The S-net is a large-scale inline-type seafloor observation network for earthquake and tsunami in the Japan Trench area. Characterization of NLSR is important because, in most common cases, it can cause a reduction of higher frequency components and a shift of predominant site frequency to lower one. Obtaining high-quality strong-motion records at seafloor sites is extremely difficult and expensive. Some of the records from the three earthquakes used in this study were contaminated by the rotations of the sensor houses, resulting in the ramps and offsets after the arrival of strong S-wave phases. We used a time window of 10 s starting from the S-wave onset, that avoided the ramps and offsets mostly. Using the horizontal-to-vertical spectral ratio (HVSR) technique, we found that the selected S-net sites might have experienced substantial degrees of NLSR during the three earthquakes with peak accelerations greater than about 60 cm/s2. To investigate that the obtained features of NLSR were realistic or not at the S-net sites, we examined the NLSR at nine KiK-net sites on land where high-quality strong-motion records were obtained. We found that the KiK-net sites experienced various degrees of NLSR during the three earthquakes, and the obtained characteristics of NLSR at the KiK-net and S-net sites were comparable. We found that the NLSR affected the ground motions at frequencies mainly higher than 1 Hz at both Kik-net and S-net sites. Despite these similarities, by analyzing the spectral ratios between two horizontal component records, we suspected that the induced rotations contributed to some extent in exaggerating the degree of NLSR at the S-net sites, primarily when the components perpendicular to the cable axes were used. We concluded that consideration of induced rotational effects is necessary to understand the NLSR at the S-net sites better.
Regulation of PD-L1 expression in non–small cell lung cancer by interleukin-1β
Authors: Hirayama Aiko , Tanaka Kentaro , Tsutsumi Hirono , Nakanishi Takayuki , Yamashita Sho , Mizusaki Shun , Ishii Yumiko , Ota Keiichi , Yoneshima Yasuto , Iwama Eiji , Okamoto Isamu 
Published: June 2023

IntroductionProgrammed cell death–ligand 1 (PD-L1) is a biomarker for prediction of the clinical efficacy of immune checkpoint inhibitors in various cancer types. The role of cytokines in regulation of PD-L1 expression in tumor cells has not been fully characterized, however. Here we show that interleukin-1β (IL-1β) plays a key role in regulation of PD-L1 expression in non–small cell lung cancer (NSCLC).MethodsWe performed comprehensive screening of cytokine gene expression in NSCLC tissue using available single-cell RNA-Sequence data. Then we examined the role of IL-1β in vitro to elucidate its induction of PD-L1 on NSCLC cells.ResultsThe IL-1β gene is highly expressed in the tumor microenvironment, particularly in macrophages. The combination of IL-1β and interferon-γ (IFN-γ) induced a synergistic increase in PD-L1 expression in NSCLC cell lines. IL-1β and IFN-γ also cooperatively activated mitogen-activated protein kinase (MAPK) signaling and promoted the binding of downstream transcription factors to the PD-L1 gene promoter. Furthermore, inhibitors of MAPK signaling blocked upregulation of PD-L1 by IL-1β and IFN-γ.DiscussionOur study reports high levels of IL-1β in the tumor microenvironment may cooperate with IFN-γ to induce maximal PD-L1 expression in tumor cells via activation of MAPK signaling, with the IL-1β–MAPK axis being a promising therapeutic target for attenuation of PD-L1–mediated suppression of antitumor immunity.
The role and safety of UVA and UVB in UV-induced skin erythema
Authors: Yang Jing-Wen , Fan Guo-Biao , Tan Fei , Kong Hai-Mei , Liu Qing , Zou Ying , Tan Yi-Mei 
Published: June 2023

BackgroundDifferent wavelengths of ultraviolet (UV) light cause skin damage through different mechanisms. Minimal erythema dose (MED) is usually used to clinically evaluate skin sensitivity to ultraviolet radiation by inducing skin erythema using ultraviolet B (UVB) or ultraviolet A (UVA) + UVB.AimsIn this study, we detected changes in the blood flow at the MED erythema caused by UVB and UVA + UVB radiation through optical coherence tomography (OCT) to explain the role of different bands of ultraviolet rays in erythema induction.MethodsTwo MED irradiation areas on the subjects' back were irradiated with UVB alone or UVA + UVB (UVA: UVB = 8:1). The absolute energy of UVB remained the same in UVB and UVA+UVB. At 24 h after the irradiation, the changes in the blood flow in the MED area were detected using OCT.ResultsCompared with the blank control, the maximum blood flow depth, blood flow peak, and total blood flow of UVB-MED and UVA+UVB-MED were significantly increased. Notably, the maximum blood flow depth and blood flow peak of UVB-MED were higher than UVA+UVB-MED. There was no significant difference in total blood perfusion between UVA+UVB-MED and UVB-MED. Under the same UVB energy, the skin erythema caused by UVA + UVB was weaker than UVB alone.ConclusionsThe analysis of local blood flow by OCT showed that the peak and maximum depth of local blood flow caused by UVB alone were significantly higher than UVA + UVB.
Is the internet a sufficient source of information on sarcoidosis?
Authors: Buschulte Katharina , Höger Philipp , Ganter Claudia , Wijsenbeek Marlies , Kahn Nicolas , Kriegsmann Katharina , Wilkens Finn M. , Fisher Jolene H. , Ryerson Christopher J. , Herth Felix J. F. , Kreuter Michael 
Published: June 2023

IntroductionMany patients use the internet as a source of health information. Sarcoidosis is a complex disease, and internet resources have not yet been analyzed for reliability and content on sarcoidosis.AimsOur study aimed to investigate the content and the quality of information on sarcoidosis provided by internet resources.MethodsGoogle, Yahoo, and Bing were searched for the term “sarcoidosis,” and the first 200 hits were saved in each case. Those websites that met the inclusion criteria (English language, no registration fees, and relevant to sarcoidosis) were then analyzed by two independent investigators for readability, quality (HON, JAMA, and DISCERN), and content (25 predefined key facts) of the provided information.ResultsThe websites were most commonly scientific or governmental (n = 57, 46%), and the median time since the last update was 24 months. Quality was rated with a median JAMA score of 2 (1; 4) and a median overall DISCERN score of 2.4 (1.1; 4.1), both scores represent partially sufficient information. In total, 15% of websites had a HON certificate. Website content measured by the median key fact score was 19 (ranging from 2.5 to 25) with the lowest scores for acute vs. chronic course of the disease, screening for extrapulmonary disease, and diffuse body pain. Poor results were achieved in industry websites and blogs (p = 0.047) with significant differences regarding definition (p = 0.004) and evaluation (p = 0.021).DiscussionSarcoidosis-related content of internet resources is partially sufficient; however, several important aspects are frequently not addressed, and the quality of information is moderate. Future directions should focus on providing reliable and comprehensive information on sarcoidosis; physicians from different disciplines and patients including self-support groups should collaborate on achieving this.
Indigenously produced biochar retains fertility in sandy soil through unique microbial diversity sustenance: a step toward the circular economy
Authors: Khan Munawwar Ali , Salman Alsayeda Zahra , Khan Shams Tabrez 
Published: June 2023

IntroductionAgricultural productivity in the arid hot desert climate of UAE is limited by the unavailability of water, high temperature, and salt stresses. Growing enough food under abiotic stresses and decreasing reliance on imports in an era of global warming are a challenge. Biochar with high water and nutrient retention capacity and acid neutralization activity is an attractive soil conditioner. This study investigates the microbial community in the arid soil of Dubai under shade house conditions irrigated with saline water and the shift in the microbial community, following 1 year of amendment with indigenously prepared biochar from date palm waste.MethodsAmplicon sequencing was used to elucidate changes in bacterial, archaeal, and fungal community structures in response to long-term biochar amendment. Samples were collected from quinoa fields receiving standard NPK doses and from fields receiving 20 and 30 tons ha−1 of biochar, in addition to NPK for 1 year. Water holding capacity, pH, electrical conductivity, calcium, magnesium, chloride, potassium, sodium, phosphorus, total carbon, organic matter, and total nitrogen in the soil from biochar-treated and untreated controls were determined.Results and discussionThe results show that soil amendment with biochar helps retain archaeal and bacterial diversity. Analysis of differentially abundant bacterial and fungal genera indicates enrichment of plant growth-promoting microorganisms. Interestingly, many of the abundant genera are known to tolerate salt stress, and some observed genera were of marine origin. Biochar application improved the mineral status and organic matter content of the soil. Various physicochemical properties of soil receiving 30 tons ha−1 of biochar improved significantly over the control soil. This study strongly suggests that biochar helps retain soil fertility through the enrichment of plant growth-promoting microorganisms.
Psychosocial interventions reduce cortisol in breast cancer patients: systematic review and meta-analysis
Authors: Mészáros Crow Edith , López-Gigosos Rosa , Mariscal-López Eloisa , Agredano-Sanchez Marina , García-Casares Natalia , Mariscal Alberto , Gutiérrez-Bedmar Mario 
Published: June 2023

IntroductionCancer initiation, progression and recurrence are intricate mechanisms that depend on various components: genetic, psychophysiological, or environmental. Exposure to chronic stress includes fear of recurrence that can affect biological processes that regulate immune and endocrine systems, increase cancer risk, and influence the survival rate. Previous studies show that psychological interventions might influence the level of cortisol that has been extensively used as a biomarker for measuring hypothalamic-pituitary-adrenal axis functioning and body's immunity response. This meta-analysis aimed to provide a quantitative scrutiny of the effect of certain types of psychosocial interventions on cortisol as a neuroendocrine biomarker in saliva or blood and might predict breast cancer (BC) progression.MethodsA literature search was performed in the following databases: PubMed, The Cohrane Library, Scopus, WOS, PsychInfo, Google Scholar, Ovid Science Direct. After methodical selection of originally generated 2.021 studies, the search yielded eight articles that met inclusion criteria. All these studies explored effects of psychosocial interventions that measured cortisol in total of 366 participants with BC, stages 0-IV, in randomized control trial or quasi experimental study design setting. We applied random effects model to conduct meta-analyses on the parameters of salivary and plasma cortisol and used PRISMA Guidelines as validated methodology of investigation to report the results.ResultsEight studies selected for meta-analysis have shown the reduction of cortisol level due to applied psychosocial intervention. The random effects model showed that interventions produced large effect sizes in reductions of cortisol in blood (Cohen's d = −1.82, 95% Confidence Interval (CI): −3.03, −0.60) and slightly less in saliva (d = −1.73, 95%CI: −2.68, −0.78) with an overall effect of d = −1.76 (95%CI: −2.46, −1.07).ConclusionOur study concluded that certain types of psychosocial interventions reduce cortisol (indicator of chronic stress) in patients with BC. Application of specific psychosocial support as adjuvant non-invasive therapy for affected females with BC at all phases of treatment could contribute to more cost-effective health care.
The effect of online collaborative writing instruction on enhancing writing performance, writing motivation, and writing self-efficacy of Chinese EFL learners
Authors: Li Yan 
Published: June 2023

IntroductionThis study investigates the influence of online collaborative writing instruction on the writing performance, writing self-efficacy, and writing motivation of Chinese English as a foreign language (EFL) learners. The research was conducted at a language school in mainland China with 58 participants divided into an experimental group (n=30) and a control group (n=28).MethodsThe experimental group utilized Tencent Docs, an online platform, for collaborative writing and peer-editing activities outside the classroom, while the control group received traditional in-class instruction. The study spanned a duration of 13 weeks, during which writing tasks, writing motivation scales, and writing self-efficacy scales were employed to collect data.ResultsThe findings revealed that the experimental group exhibited significantly greater improvement in writing performance, motivation, and self-efficacy compared to the control group. These results indicate the positive impact of incorporating Tencent Docs into collaborative writing instruction.DiscussionThe outcomes of this study provide valuable insights for language educators regarding the benefits of integrating online tools into EFL instruction to enhance writing skills. By leveraging platforms like Tencent Docs for collaborative writing, instructors can foster improved performance, increased motivation, and enhanced self-efficacy among EFL learners. Overall, this research highlights the effectiveness of online collaborative writing instruction and its potential as a valuable tool for language educators seeking to optimize EFL learners’ writing abilities.
Impact of longer working hours on fathers’ parenting behavior when their infants are 6  months old: The Japan Environment and Children’s Study
Authors: Kasamatsu Haruka , Tsuchida Akiko , Matsumura Kenta , Hamazaki Kei , Inoue Mariko , Inadera Hidekuni ,   the Japan Environment and Children’s Study Group
Published: June 2023

ObjectiveLong working hours have been suggested to affect fathers’ parenting behavior, but previously reported findings have been inconsistent. This study examined the association between the working hours and parenting behavior of fathers while accounting for other factors related to their parenting behavior, using data from the Japan Environment and Children Study (JECS), a large cohort study in Japan.MethodsData from 43,159 father–mother pairs were analyzed. The mother assessed the father’s frequency of seven parenting behaviors at 6 months after delivery. Then, each behavior was classified into a high-engagement group (always and sometimes) or a low-engagement group (rarely and never). The father’s weekly working hours was obtained from his responses and was classified into six levels.ResultsLogistic regression analysis showed that after adjustment for covariates, fathers’ weekly working hours was inversely associated with the frequency of all parenting behaviors examined in this study (p for trend &lt;0.0001). Compared with fathers working ≥0 to ≤40 h per week, those working &gt;65 h per week showed the following adjusted odds ratios (95% confidence intervals) for low engagement in parenting behaviors: playing at home, 2.38 (2.08–2.72); changing diapers, 2.04 (1.89–2.20); and bathing the child, 2.01 (1.84–2.18).ConclusionThis study suggests that the greater time constraints imposed by longer working hours constitute a major factor that discourages fathers from engaging in childrearing behavior. Intervention targeting long working hours could contribute to measures aimed at promoting high-engagement parenting behaviors among fathers.
Prevalence of depression and its correlation with anxiety, headache and sleep disorders among medical staff in the Hainan Province of China
Authors: Lu Guangshuang , Xiao Shaobo , He Jiaji , Xie Wei , Ge Wei , Meng Fanchao , Yang Ying , Yu Shengyuan , Liu Ruozhuo 
Published: June 2023

ObjectiveThis cross-sectional survey aimed to investigate the prevalence of depression among medical staff and its risk factors as well as the association between depression, anxiety, headache, and sleep disorders.MethodsStratified random cluster sampling was used to select medical staff from various departments of four hospitals in Sanya City. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), and Pittsburgh Sleep Quality Index (PSQI) were used to quantitatively assess depression, anxiety, and sleep disorders. Correlation and regression analyses were performed to determine factors affecting the depression occurrence and scores.ResultsAmong 645 medical staff members, 548 (85%) responded. The 1-year prevalence of depression was 42.7% and the prevalence of depression combined with anxiety, headache, and sleep disorders was 23, 27, and 34.5%, respectively. The prevalence of depression in women, nurses, the unmarried or single group, and the rotating-shift population was significantly higher than that in men (48.3% vs. 27.1%, odds ratio OR = 2.512), doctors (55.2% vs. 26.7%, OR = 3.388), the married group (50.5% vs. 35.8%, OR = 1.900), and the day-shift population (35.2% vs. 7.5%, OR = 1.719). The occurrence of depression was correlated with anxiety, sleep disorders, headache, and migraines, with anxiety having the highest correlation (Spearman’s Rho = 0.531). The SDS was significantly correlated with the SAS and PSQI (Spearman’s Rho = 0.801, 0.503) and was also related to the presence of headache and migraine (Spearman Rho = 0.228, 0.159). Multiple logistic regression indicated that nurse occupation and anxiety were risk factors for depression, while grades of anxiety, sleep disorders and nurse occupation were risk factors for the degree of depression in multiple linear regression.ConclusionThe prevalence of depression among medical staff was higher than that in the general population, especially among women, nurses, unmarried people, and rotating-shift workers. Depression is associated with anxiety, sleep disorders, headache, and migraines. Anxiety and nursing occupation are risk factors for depression. This study provides a reference for the promotion of occupational health among medical professionals.