bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accuracy of the Bair Hugger™ Core Body Temperature in Wrist Regions: Prospective Observational Study.
Authors: Oh Kyung Seo , Park Yong-Hee , Kang Hyun , Baek Chongwha , Woo Young-Cheol 
Published: May 2023

Abstract
Purpose: Monitoring body temperature is essential during perioperative period. Core body temperature requires invasive device that may cause complications. We aim to study accuracy of non-invasive Bair Hugger™ core body temperature monitoring system (BHTMS) at wrist compared to esophageal temperature under general anesthesia.
Methods: Twenty adult patients of American Society of Anesthesiologists physical status I or II were enrolled in this study. BHTMS sensor was applied to wrist. After tracheal intubation, esophageal probe was inserted. Bair Hugger™ upper body warming blankets were applied. Esophageal temperature (Teso) and wrist temperature (Twrist) were recorded every 10 minutes.
Results: Total 257 pairs of data set were analyzed and T_eso and T_wrist had statistically no significant difference (P = 0.103). Median of T_eso and T_wrist were 36.5℃ and 36.4℃. Bland-Altman analysis showed Teso - Twrist of 0.14℃ (2SD ± 1.44℃). Ninety-nine pairs of data set from 0 to 40 minute were analyzed and showed significant difference at 0, 10 minute (P < 0.001) and no significant difference at 20, 30, 40 minutes. Bland-Altman plot by times showed difference (Teso - Twrist) of 1.49℃, 0.82℃, 0.29℃, -0.03℃, -0.12℃ (2SD ± 2.00℃, ± 1.30℃, ± 1.32℃, ± 0.84℃, ± 0.82℃) at 0, 10, 20, 30, 40 minutes respectively.
Conclusions: BHTMS at wrist area under upper body warm blanket may be another possible alternative method for monitoring core body temperature after 30 minutes compared to esophageal temperature.
IRB number: 2112-030-489 (Date: 20220314)
Clinical trial registration number: KTC0007211 (Date: 20220317)
Predicting postoperative lung function in lung cancer patients by using imaging biomarkers
Authors: Kwon Oh-Beom , Lee Hae-Ung , Park Ha-Eun , Choi Joon-Young , Kim Jin-Woo , Lee Sang-Haak , Yeo Chang-Dong 
Published: May 2023

Abstract
Background There were previous studies to predict postoperative lung function with pulmonary function test (PFT). Computing tomography (CT) can quantitatively measure small airway wall thickness, lung volume, pulmonary vessel volume, and emphysema area, which reflect the severity of respiratory diseases. These measurements are considered as imaging biomarkers. This study aimed to predict postoperative lung function with imaging biomarkers.
Methods Retrospective analysis of 79 lung cancer patients who underwent lung surgery was completed. Postoperative lung function measured by forced expiratory volume in one second (FEV1) was defined as an outcome. Preoperative clinico-pathological parameters and imaging biomarkers representing airway wall thickness, severity of emphysema, total lung volume, and pulmonary vessel volume were measured quantitatively in chest CT by an automated segmentation software, AVIEW COPD. Logistic and linear regression were used to assess these variables. If the actual postoperative FEV1 was higher than the projected postoperative FEV1 by a formula, the group was considered to be preserved.
Results Among 79 patients, 16 patients were grouped as a non-preserved group and 63 were grouped as a preserved group. Patients in the preserved FEV1 group had a higher vessel volume than the non-preserved group. Pi1 and Wafw were independent predictors of postoperative lung function.
Conclusion Imaging biomarkers can be considered as significant variables in predicting postoperative lung function in patients with lung cancer.
“You Don`t Go Out If You Don’t See Anyone” – Reconsidering the Interplay of Personal, Social and Environmental Resources for Life-Space Mobility in Old Age”
Authors: Mümken Sandra Angelika , Haeger Christine , Herrmann Wolfram J. , Gellert Paul 
Published: May 2023

Abstract
Maintaining mobility with increasing age depends on personal, social and environmental factors, but the understanding of their complex interplay remains limited. Considering the comprehensive concept of Life-space mobility (LSM), we aim to illustrate the synergistic or antagonistic interplay of personal, social and environmental factors for life-space mobility (LSM) of older adults living in rural areas. Semi-structured interviews with twelve older adults (74–95 years) from a particularly rural area in Germany were conducted alongside the validation study of the German version of the Life-Space Assessment (DRKS00019023). To analyze interview transcripts methods of qualitative content analysis were applied using MAXQDA 2020. Participants were additionally characterized with assessments of LSM, everyday functioning, quality of life and balance confidence were carried out. Eight participants reported restricted LSM. Qualitative analysis displayed that difficulties visiting healthcare services were related to accessible information and dependence on being driven there. Additionally, factors cancelled each other out, e.g., the motivation to go out was facilitated by modernized sidewalks but subverted by the absence of social contacts. Findings related to social and environmental factors turned out to be ambivalent. For instance, the spouse who helped his wife to be mobile outdoors also undermined her motivation to go out. Results reveal various forms of interplay of personal, social and environmental factors providing an enriched understanding of emerging barriers to LSM as well as resource allocation to maintain LSM in old age.
Aflatoxin B1 (AFB1) induced free radicals cause encephalopathy in goat kids via intrinsic pathway of apoptosis: Pathological and immunohistochemical confirmation of non-hepatic neuroaflatoxicosis
Authors: Sahoo Monalisa , Thakor Jigarji , Kumar Pradeep , Singh Rajendra , Kumar Pawan , Singh Karampal , Puvvala Bhavani , Kumar Ajay , Gopinathan Aswathy , Palai Santawana , Patra Sushmita , Tripathy Jagannath Prasad , Acharya Ramakanta , Sahoo Nihar , Behera Pratima 
Published: May 2023

Abstract
Aflatoxins, particularly Aflatoxin B1 (AFB1), are the most common feed contaminants worldwide, causing significant economic losses to the livestock sector. The current paper describes an outbreak of aflatoxicosis in a herd of 160 male young goat kids (3–4 months), of which 68 young kids succumbed over a period of 25 days after showing neurological signs of abnormal gait, progressive paralysis and head pressing. The haematobiochemical investigation showed reduced haemoglobin, leucocyte count, PCV level, increased levels of AST, ALT, glucose, BUN, creatinine and reduced level of total protein. Grossly, kids had pale mucous membranes, pale and swollen liver; right apical lobe consolidation, and petechiation of the synovial membrane of the hock joints. The microscopic changes were characterized by multifocal hemorrhages, status spongiosus/ vacuolation, vasculitis, focal to diffuse gliosis, satellitosis, and ischemic apoptotic neurons in different parts of the brain and spinal cord. These changes corresponded well with strong immunoreactivity for AFB1 in neurons, glia cells (oligodendrocytes, astrocytes, and ependymal cells) in various anatomical sites of the brain. The higher values of LPO and reduced levels of antioxidant enzymes (Catalase, SOD, GSH) with strong immunoreactivity of 8-OHdG in the brain indicating high level of oxidative stress. Further, the higher immunosignalling of caspase-3 and caspase-9 in the brain points towards the association with intrinsic pathway of apoptosis. The toxicological analysis of feed samples detected high amounts of AFB1 (0.38ppm). These findings suggest that AFB1 in younger goat kids has more of neurotoxic effect mediated through caspase dependent intrinsic pathway, than hepatic toxicity.
Sacubitril/Valsartan Effects on Right Ventricular-Pulmonary Coupling and Albumin-bilirubin Score in Heart Failure with Reduced Ejection Fraction in China
Authors: Xu Yu , Gao ChuanYu , Xu Yu , Yuan Fang 
Published: May 2023

Abstract
Background
Impaired right ventricular (RV) function coupled with progressive uncoupling of the pulmonary circulation (PA) represents a turning point in clinical deterioration with profound consequences for prognosis. Several studies have proposed that RV-PA coupling, calculated by measuring the tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (PASP), can be used as an early indicator of right ventricular dysfunction(RVD) in patients with heart failure with a reduced ejection fraction (HFrEF). Patients with HFrEF benefit from sacubitril/valsartan therapy in terms of left ventricular (LV) function as well as functional and symptomatic improvement. The objective of this study was to evaluate the effect of sacubitril/valsartan treatment on TAPSE/PASP in patients with HFrEF.
Methods
A retrospective observational study was conducted on 305 patients with HFrEF and RVD who were hospitalized between June 2020 and December 2021.One year after treatment, we reevaluated laboratory tests, transthoracic echocardiography (TTE), NYHA(New York Heart Association) classification, Minnesota Living with Heart Failure Questionnaire (MLWHFQ) scores and changes in relevant variables.
Results
A significant improvement was demonstrated in the following echocardiography parameters assessing RV function after 1 year of treatment with sacubitril/valsartan:TAPSE (15 ± 1 vs. 18 ± 2 mm,p < 0.001), PASP (45 ± 8 vs. 40 ± 9mmHg,p < 0.001), Pulmonary artery diastolic pressure(PADP)(22 ± 4 vs. 19 ± 4mmHg, p < 0.001),RV-PA coupling (0.35 ± 0.08 vs. 0.48 ± 0.12,p < 0.001),and RV s’(8.7 ± 2.2 vs. 9.5 ± 2.6 cm/s, p < 0.001). Multivariable analysis showed that RV-PA coupling improved with baseline PASP (r-0.45, p < 0.001) and PADP (r-0.45, p < 0.001).
Conclusions
Sacubitril/valsartan improves RV-PA conjugation in patients with RVD and HFrEF, however, this effect may not be a result of left ventricular remodeling, but rather a result of reduced left atrial pressure.
Effect of electric field intensity on energy consumption and removal efficiency of chromium ions from salt-affected clayey soils
Authors: Hussain Abdul Ahad , Kamran Kashif , Waseem Muhammad , Akram Aasma 
Published: May 2023

Abstract
This study investigates the effect of electric field intensity on electroosmosis and the effects of potential distribution, current and pH on the removal of total Cr, Na+, Clˉ and K+ ions from salt-effected clayey soils. During electrokinetic experiments, DC electric field intensities varying from 0.5 to 2 Vcm− 1 were applied across the artificially contaminated soil samples for 48 hours. The results depict that the electric field intensity directly influences the electroosmotic flow and electromigration of ionic species presented in the pore solution of the specimens. The maximum removal of total Cr (~ 71%), Na+ (~ 91%), Clˉ (~ 65%) and K+ (~ 63%) was achieved at 2 Vcm− 1 due to the electromigration and initially higher electroosmotic flow (i.e., 69 ml). However, the higher electric field intensity resulted in enhanced electric energy consumption (i.e., 218.6 kWhr-m− 3) and the production of more aggressive acidic and alkaline environments across the electrodes. Thus, the migration of ions and electroosmosis were inhibited due to the higher potential drop caused by the collusion of pH fronts. Moreover, under an electric field intensity of 2 Vcm− 1, the electrical conductivity of soil reduced from 5.2 to 1.29 dS m− 1.
The determinants of handwashing during the COVID-19 pandemic: A multi-country analysis of data from the Wash’Em process for hygiene programme design
Authors: Lamb Jenny , Thorseth Astrid Hasund , MacDougall Amy , Thorsen William , White Sian 
Published: May 2023

AbstractBackground The Wash’Em process was developed to improve the design of handwashing behaviour change programmes in outbreaks and fragile humanitarian settings, ensuring that programmes are able to be designed rapidly while still being contextualised and evidence-based. The approach was widely used during the COVID-19 pandemic to inform prevention programmes. This study aims to compare data emerging from the use of the Wash’Em process during the pandemic, to understand whether commonalities in programming constraints or the determinants of handwashing behaviour existed across countries. Methods We conducted a secondary data analysis of summary data entered into the Wash’Em Programme Designer Software. This summary data was drawn from the use of the Wash’Em Rapid Assessment Tools in 38 settings during the pandemic. Data was verified prior to inclusion; descriptively summarised and then statistical summaries of homogeneity were derived. Results Wash’Em was implemented as intended during the pandemic, typically taking a small number of humanitarian staff less than a week to complete. Most humanitarian actors reported using the programmatic recommendations suggested by the process but did so within relatively short-term and poorly financed prevention programmes. Homogeneity in the responses to the Rapid Assessment Tools was low indicating that the determinants of handwashing behaviour during the pandemic were predominantly shaped by pre-existing factors within the context rather than the nature of the health threat. Conclusion Hygiene programmes during outbreaks should avoid ‘copying and pasting’ interventions from one setting to another and instead make time to holistically understand the behavioural determinants in a specific context and develop programme activities that are designed to address these. Particular attention should be given to factors in the physical and social environment which may enable or constrain handwashing behaviour, pre-existing disease vulnerabilities, and the secondary and non-health impacts of outbreaks. Wash’Em provides one feasible way of contextualising handwashing interventions in outbreak or fragile humanitarians settings.
2d Qsar and Docking Studies on Chalcone - Quinoxaline Variants – a Potential Target for Acetylcholinestrase Inhibitors
Authors: VELMURUGAN BALA AAKASH , SIVARAMAN BHUVANESWARI , NATARAJAN RAMALAKSHMI 
Published: May 2023

AbstractThe Quantitative Structural Activity Relationship among 49 reported compounds containing chalcone derivatives as an acetylcholinesterase inhibitor. The acetylcholinesterase enzyme is the major leading threat to neurodegenerative disorders. The 2D QSAR study was done using QSARINS software. Model 2 was obtained as the best model with an r2value of 0.9398. The OECD principles were used to validate the model. The applicability domain of the model resulted in zero outliers. Based on the results of the QSAR study, 10 novel ligands possessing chalcones fused with quinoxaline were drawn. These 10 novel ligands showed class 5 toxicity, which was predicted using PROTOX II software. The ADME properties were also screened using preADMET. Molecular docking was performed between the 10 ligands and the acetylcholinesterase enzyme (PDB ID: 4EY7) using Autodock 4.0 softaware. 2D visualisation of drug interactions was also discussed. Compounds 4 and 5 with substitution of p-chloro and 2-bromo respectively demonstrated active binding to the catalytic anionic site and the peripheral anionic site, respectively. These results were compared with those of the standard drug, donepezil.
Limits of Thermal Insulations – Heat Transfer within Evacuated Porous High-Performance Insulations
Authors: Ebert Hans-Peter , Manara Jochen , Reichenauer Gudrun 
Published: May 2023

Abstract
High-performance thermal insulations (HPI) have outstanding thermal properties to minimize heat transfer for a specific application. The term "high performance" is a relative rating: whether an insulating property, i.e. the thermal conductivity or thermal transmittance, is significantly lower than those of conventional insulating materials or systems depends on the use case and the related conditions. Applications fields for thermal insulations are the energy, building, industry and transport sector, but also the space and aviation industry. The total effective thermal conductivity of evacuated HPI depends on the contributions of the heat transfer via the solid skeleton of the porous insulation material and the radiative heat exchange. For a given operating temperature, the effective thermal conductivity yields a minimum depending on the density and the infrared-optically extinction properties of the insulation material. Examples for HPI with outstanding low thermal conductivity values will be presented and compared with the theoretical predictions based on a percolation model for the solid thermal conductivity of the skeleton and on a diffusion model for the radiative heat transfer.
Classification of sympathetic skin response based on the morphologic features and Adaptive Neuro Fuzzy Inference system( ANFIS)
Authors: dhouibi nourhene , ALI Jaouher BEN , SAYADI Mounir , GRAPPERON Jacques , GINOUX Jean-Marc 
Published: May 2023

Abstract
The prevalence of polyneuropathy (PNP) or peripheral neuropathy (PN) is estimated to be 2%-3% in the general population and may be as high as 8% in people over 55 years of age. It’s the most common type of disorder of the peripheral nervous system in adults and in the elderly. Early detection and accurate classification of PNP can lead to proper diagnosis and treatment of painful symptoms. Our team developed a new method to classify the presence or absence of PNP in a database based on Adaptive Neuro Fuzzy Inference system( ANFIS) using sympathetic skin response (SSR) signal. To realize an efficient detection the output of our classification is divided into four classes such as the severity of PNP: no-PNP, mild, moderate, and severe class. In fact, we propose to extract the morphologic features of SSR signal including Latency, amplitude, rise time, the typical recovery time of 63%, and the typical recovery time of 50% which can be altered by PNP. Thus, the performances of the PNP severity classification system were compared with different machine learning (ML) algorithms such as support vector machine (SVM), K-nearest neighbor (KNN). Hence, The ANFIS model showed better performance in comparison to different ML models. In the classification stage, the best classification performance was achieved as 97.16%, 84.40%, and 87.12%% using ANFIS, KNN, and SVM classifier respectively.
Conspecific interactions predict social transmission of fear in female rats
Authors: Seese Sydney , Tinsley Carolyn E , Wulffraat Grace , Hixon J. Gregory , Monfils Marie H. 
Published: May 2023

AbstractSocial transmission of fear occurs in a subset of individuals, where an Observer displays a fear response to a previously neutral stimulus after witnessing or interacting with a conspecific Demonstrator during fear memory retrieval. The conditions under which fear can be acquired socially in rats have received attention in recent years, and suggest that social factors modulate social transmission of information. We previously found that one such factor, social rank, impacts fear conditioning by proxy in male rats. Here, we aimed to investigate whether social roles in females also have an influence on social transmission of fear. In-line with previous findings in males, we found that social interactions in the home cage can provide insight into the social relationship between female rats and that these relationships predict the degree of fear acquired by-proxy. These results suggest that play behavior may provide a valuable assessment of dominance hierarchy in female rats.
Probiotic Potential, Antibacterial and Antioxidant Capacity of Aspergillus luchuensis YZ-1 Isolated from Liubao Tea
Authors: Zhang Xiyan , Jiao Rui , Li Hui , Ou Dexin , Zhang Danfeng , Shen Yizhong , Ling Na , Ye Yingwang 
Published: May 2023

Abstract
Aspergillus fungi are widely used in the traditional fermentation of food products, so their safety risks and functions are worthy of investigation. In this study, one Aspergillus luchuensis YZ-1 isolated from Liubao tea was identified based on phylogenetic analyses of sequences of three genes coding for internal transcribed spacer 1 (ITS1), β-tubulin (benA) and calmodulin (CaM). The results of hemolytic activity, Dnase activity, cytotoxicity assay and antibiotic resistance assay indicated that the strain is potentially safe. The excellent gastrointestinal fluids tolerance, acid tolerance, bile tolerance, auto-aggregation, co-aggregation, cell surface hydrophobicity and adhesion to human colon adenocarcinoma (HT29) cell line were observed on analysis of the probiotic properties. Furthermore, the results of the antibacterial activity of A. luchuensis YZ-1 indicated that the strain had strong antagonistic effects against Gram-negative and Gram-positive bacteria as well as fungi. Simultaneously, the water extracts and 80% ethanolic extracts of A. luchuensis YZ-1 cells also showed strong ABTS, DPPH and OH− scavenging ability. Taken together, our results suggest that A. luchuensis YZ-1 has desirable functional probiotic properties and can be proposed as a biocontrol agent in the food industry.
Motion Events in English Language Teaching: An investigation of Manner in the context of Australia, Iran, and Turkey
Authors: Banaruee Hassan , Farsani Danyal , Khatin-Zadeh Omid , Eskandari Zahra , Askari Afsane 
Published: May 2023

AbstractMotion events have been the target of many studies since their introduction by Talmy (1985). The overwhelming majority of investigations have compared languages cross-culturally with English and Spanish (see, Slobin, 1996, 2004, 2005). The literature is ultimately in need of the practice of this cognitive typology. Since motion events represent cognitive styles and conceptualizations, language teaching and learning is a controversial subject of investigation. To provide insights and contribute to the development of English Language Teaching (ELT) worldwide, we conducted this interdisciplinary study on the verge of cognitive linguistics and ELT. We compared EFL textbooks taught in Iran and Turkey, employing the context of Australia as the source of comparison as the target language. Data were collected from two corpora; one consisting of three English textbooks taught at high schools and one consisting of three novels in each language. Having analyzed the motion components in the corpora, we discovered the discrepancies and diversity of patterns in the languages and the corresponding English textbooks. A detailed comparison ofMannerin these languages revealed that Talmy's typology needs further investigations for a more robust classification of languages. The EFL textbooks in Iran and Turkey do not fully picture English cognitive structures.