bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marine protected areas, marine heatwaves, and the resilience of nearshore fish communities
Authors: Ziegler Shelby L. , Johnson Jasmin M. , Brooks Rachel O. , Johnston Erin M. , Mohay Jacklyn L. , Ruttenberg Benjamin I. , Starr Richard M. , Waltz Grant T. , Wendt Dean E. , Hamilton Scott L. 
Published: January 2023

AbstractAnthropogenic stressors from climate change can affect individual species, community structure, and ecosystem function. Marine heatwaves (MHWs) are intense thermal anomalies where water temperature is significantly elevated for five or more days. Climate projections suggest an increase in the frequency and severity of MHWs in the coming decades. While there is evidence that marine protected areas (MPAs) may be able to buffer individual species from climate impacts, there is not sufficient evidence to support the idea that MPAs can mitigate large-scale changes in marine communities in response to MHWs. California experienced an intense MHW and subsequent El Niño Southern Oscillation event from 2014 to 2016. We sought to examine changes in rocky reef fish communities at four MPAs and associated reference sites in relation to the MHW. We observed a decline in taxonomic diversity and a profound shift in trophic diversity inside and outside MPAs following the MHW. However, MPAs seemed to dampen the loss of trophic diversity and in the four years following the MHW, taxonomic diversity recovered 75% faster in the MPAs compared to reference sites. Our results suggest that MPAs may contribute to long-term resilience of nearshore fish communities through both resistance to change and recovery from warming events.
Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
Authors: Ghezzi Chiara , Chen Bao Ying , Damoiseaux Robert , Clark Peter M. 
Published: January 2023

AbstractSquamous cell lung cancer maintains its growth through elevated glucose consumption, but selective glucose consumption inhibitors are lacking. Here, we discovered using a high-throughput screen new compounds that block glucose consumption in three squamous cell lung cancer cell lines and identified 79 compounds that block glucose consumption in one or more of these cell lines. Based on its ability to block glucose consumption in all three cell lines, pacritinib, an inhibitor of FMS Related Receptor Tyrosine Kinase 3 (FLT3) and Janus Kinase 2 (JAK2), was further studied. Pacritinib decreased glucose consumption in squamous cell lung cancer cells in cell culture and in vivo without affecting glucose consumption in healthy tissues. Pacritinib blocked hexokinase activity, and Hexokinase 1 and 2 mRNA and protein expression. Overexpression of Hexokinase 1 blocked the ability of pacritinib to inhibit glucose consumption in squamous cell lung cancer cells. Overexpression of FLT3 but not JAK2 significantly increased glucose consumption and blocked the ability of pacritinib to inhibit glucose consumption in squamous cell lung cancer cells. Additional FLT3 inhibitors blocked glucose consumption in squamous cell lung cancer cells. Our study identifies FLT3 inhibitors as a new class of inhibitors that can block glucose consumption in squamous cell lung cancer.
City comfort: weaker metabolic response to changes in ambient temperature in urban red squirrels
Authors: Wist Bianca , Montero B. Karina , Dausmann Kathrin H. 
Published: January 2023

AbstractThe ecophysiological responses of species to urbanisation reveal important information regarding the processes of successful urban colonization and biodiversity patterns in urban landscapes. Investigating these responses will also help uncover whether synurban species are indeed urban ‘winners’. Yet we still lack basic knowledge about the physiological costs and overall energy budgets of most species living in urban habitats, especially for mammals. Within this context, we compared the energetic demands of Eurasian red squirrels (Sciurusvulgaris) from the core of an urban environment with those from a nearby forest. We measured oxygen consumption as a proxy for resting metabolic rate (RMR) of 20 wild individuals (13 urban, 7 forest), at naturally varying ambient temperature (Ta) in an outdoor-enclosure experiment. We found that the variation in RMR was best explained by the interaction between Ta and habitat, with a significant difference between populations. Urban squirrels showed a shallower response of metabolic rate to decreasing Ta than woodland squirrels. We suggest that this is likely a consequence of urban heat island effects, as well as widespread supplemental food abundance. Our results indicate energy savings for urban squirrels at cooler temperatures, yet with possible increased costs at higher temperatures compared to their woodland conspecifics. Thus, the changed patterns of metabolic regulation in urban individuals might not necessarily represent an overall advantage for urban squirrels, especially in view of increasing temperatures globally.
Evaluation of the potential of miR-21 as a diagnostic marker for oocyte maturity and embryo quality in women undergoing ICSI
Authors: Jenabi Maryam , Khodarahmi Parvin , Tafvizi Farzaneh , Bostanabad Saeed Zaker 
Published: January 2023

AbstractMicroRNAs are small molecules that play a crucial role in regulating a woman's reproductive system. The present study evaluates the expression of miR-21 in the serum, follicular fluid (FF), and cumulus cells (CCs) and their association with oocyte maturity and embryo quality in women undergoing intracytoplasmic sperm injection. Women subjects were divided into the case (54 Patients with female factor infertility) and control groups (33 patients with male factor infertility). The level of miR-21 was measured using Real-Time PCR. The level of miR-21 was significantly lower in the CCs, FF, and serum in the case compared to the control group (p < 0.05). MiR-21 abundance was higher in FF and CCs samples than in serum. Furthermore, there was a significant increase in CCs to FF in the case group (p < 0.05). A significant decrease in oocyte count, MII oocytes, and percentage of mature oocytes were observed in the case group (p < 0.05). The expression of miR-21 in FF and CCs was positively related to oocyte maturation, but no correlation with embryo development was observed. This study found that miR-21 is expressed less in women with female factor infertility, and human oocytes' development is crucially affected by the expression of miR-21. Therefore, miR-21 could provide new helpful biomarkers of oocyte maturity.
Phy-Q as a measure for physical reasoning intelligence
Authors: Xue Cheng , Pinto Vimukthini , Gamage Chathura , Nikonova Ekaterina , Zhang Peng , Renz Jochen 
Published: January 2023

AbstractHumans are well versed in reasoning about the behaviours of physical objects and choosing actions accordingly to accomplish tasks, while this remains a major challenge for artificial intelligence. To facilitate research addressing this problem, we propose a new testbed that requires an agent to reason about physical scenarios and take an action appropriately. Inspired by the physical knowledge acquired in infancy and the capabilities required for robots to operate in real-world environments, we identify 15 essential physical scenarios. We create a wide variety of distinct task templates, and we ensure that all the task templates within the same scenario can be solved by using one specific strategic physical rule. By having such a design, we evaluate two distinct levels of generalization, namely local generalization and broad generalization. We conduct an extensive evaluation with human players, learning agents with various input types and architectures, and heuristic agents with different strategies. Inspired by how the human intelligence quotient is calculated, we define the physical reasoning quotient (Phy-Q score) that reflects the physical reasoning intelligence of an agent using the physical scenarios we considered. Our evaluation shows that (1) all the agents are far below human performance, and (2) learning agents, even with good local generalization ability, struggle to learn the underlying physical reasoning rules and fail to generalize broadly. We encourage the development of intelligent agents that can reach the human-level Phy-Q score.
A Review on the Milestones of Blue Light-Emitting Materials in India
Authors: Odedara Nisha , Borane Niteen , Patel Rahul , Boddula Rajamouli 
Published: January 2023

Since 1987 in the field of optoelectronics, organic light-emitting diodes (OLEDs) have secured their position because of their extreme use in panels of lighting applications such as TV and smartphone displays. At present, OLEDs are at top-notch position in the lighting market for their promising features. The field of OLEDs is rapidly growing day by day in academia and industry due to the success of OLEDs in the form of excellent efficiency, feasible methods, excellent lifetime, color purity, and superb device architecture. As a result, OLEDs are new profitable leading devices of the 21st century. However, the OLED industry has evolved in optoelectronics in the last 30 years and is advancing rapidly just because of the development in OLED materials (fluorescent, phosphorescent, thermally activated delayed fluorescent, and blue light-emitting materials). Blue light-emitting materials have achieved incredible popularity nationally and internationally. At the international level, USA, Japan, Korea, and Germany are at the top of the list in the production of OLEDs. India has also seen rapid progress in OLED development in the last 12 years and details of research in blue OLEDs by key players of India are involved in this report.1 Introduction1.1 OLED Construction1.2 Working of OLED2 OLED Development2.1 Historical Background of OLED2.1.1 International Status2.1.2 National Status3 Progress of Blue Emitters in India4 Present Scenario of Blue OLEDs5 Conclusions and Outlook
A Novel Treatment of Pediatric Atlanto-Occipital Dislocation with Nonfusion Using Muscle-Preserving Temporary Internal Fixation of C0-C2: Case Series and Technical Note
Authors: Holy Marek , Szigethy Lilla , Joelson Anders , Olerud Claes 
Published: January 2023

Abstract
Study Design Case series with surgical technical note.
Objectives This article reports experiences and results of muscle-preserving temporary C0-C2 fixation for the treatment of atlanto-occipital dislocation (AOD).
Methods AOD is a rare injury caused by high-energy trauma, occurring in less than 1% of pediatric trauma patients. Recommended treatment is C0-C2 fusion which, however, will result in significant loss of mobility in the craniocervical junction (CCJ), especially C1-C2 rotation. An alternative approach, with the ability of preserving mobility in the C1-C2 segment, is a temporary fixation that allows the ligaments to heal, after which the implants can be removed to regain function in the CCJ joints. By using a muscle-preserving approach and navigation for the C2 screws, a relatively atraumatic fixation of the CCJ can be achieved with motion recovery after implant removal.
Results We present two cases of AOD treated with temporary fixation. A 12-year-old boy involved in a frontal car collision, as a strapped back seat passenger, was treated with temporary C0-C2 fixation for 10 months. Follow-up at 11 months after implant removal included clinical evaluation, computed tomography, magnetic resonance imaging (MRI), and flexion-extension X-rays. He was free of symptoms at follow-up. The CCJ was radiographically stable and he had 45 degrees of C1-C2 rotation.A 7-year-old girl was hit by a car as she got off a bus. She was treated with temporary fixation for 4 months after which the implant was removed. Follow-up at 8 years included clinical evaluation and MRI in rotation. She was free of symptoms. The ligaments of the CCJ appeared normal and her C1-C2 rotation was 30 degrees.
Conclusion C0-C2 fixation without fusion allows the CCJ ligaments to heal in pediatric AOD. By removing the implants after ligament healing, rotation in the C1-C2 segment can be regained without subsequent instability. Both our patients tolerated the treatment well and were free of symptoms at follow-up.By using minimally invasive muscle-preserving technique and navigation, temporary fixation of the CCJ can be achieved with minimal damage to the soft tissues allowing recovery of almost normal function after implant removal.
Migrant associations, other social networks of Portuguese Diaspora, and the modern political engagement of non-resident citizens
Authors: Góis Pedro , Marques José 
Published: January 2023

AbstractPortuguese emigration has a long global history and, in recent decades, has increased substantially and diversified its range of destinations. Recent emigration, predominantly to the European Union and Lusophone countries in Africa, complemented the traditional 19th to twentieth centuries’ waves of emigration to the Americas. The Portuguese Diaspora is multigenerational and globally distributed, although diverse. How are those generations of migrants organized within the local spaces of the Diaspora? Based on an innovative survey of more than 500 Portuguese Diaspora organisations, this paper shows how migrant engagement policies and practices are evolving and dealing with the new types of Diaspora relations, organisations and institutions. The main output of this research is an exploratory typology of the contemporary apparatuses of these Portuguese Diaspora systems and their nodes. This typology characterises the modern political engagement of non-resident citizens through their participation in associations and other social networks. With this pioneering paper, we intend to open a discussion regarding the means and forms available to mobilise current and past emigrant groups within a meaningful Diaspora policy.
“I can migrate, but why should I?”—voluntary non-migration despite creeping environmental risks
Authors: Mallick Bishawjit , Priovashini Chup , Schanze Jochen 
Published: January 2023

Abstract‘Environmental non-migration’ refers to the spatial continuity of an individual’s residence at the same place despite environmental risk. Moreover, this is a largely under-researched topic, especially within the climate change adaptation discourse, but is increasingly coming to the attention of scientists and policymakers for sustainable adaptation planning. So far, there exists hardly any conceptual and methodical guidelines to study environmental non-migration. Considering this research gap, this paper explores environmental non-migration based on the notion that factors of livelihood resilience can partly explain the decision to non-migration. Here, livelihood resilience is seen as an outcome of the interactions between societal and environmental conditions of an individual household. These conditions inform the decisions (to stay or to migrate) taken in case of a hazard or creeping environmental change. Their influence generalises the spectrum of migration decision-making (to stay or to migrate), which is conceptualised by four broad outcomes categorised into voluntary and involuntary, and non-migrants and migrants. This analytical concept is operationalised through an empirical example in southwest coastal Bangladesh. The results suggest that the Livelihood Resilience Index (LRI) relates to the voluntary nature of migration decisions once they are made. Still, only a household’s resilience cannot predict the decisions the household makes to stay or migrate. The paper concludes that the proposed analytical concept, with its exemplary factors, maybe an initial means to holistically explore migration decisions in the context of natural hazards and climate and environmental change. However, environmental non-migration remains complex and multi-faceted, and its assessment requires deeper examination at various scales.
Modelling of risk factors that influence malaria infection using Binary Logistic Regression
Authors: Darnius Open , Siahaan Dessy 
Published: January 2023

Abstract
Malaria is a parasitic disease that is currently endemic in many countries, including in Indonesia. Batubara District in North Sumatera is one of the malaria-endemic areas. This study was conducted to make a mathematical model based on risk factors that influence malaria infection. The data used is secondary data from other researchers. The method used to model risk factors that influence malaria infection is the binary logistic regression with a categorical response variable, namely diagnosis by microscopic examination. There are 10 variable predictors; mosquito nets (X
1), quality use of mosquito nets (X
2), condition of the livingenvironment (X
3), knowledge (X
4), attitudes (X
5), actions (X
6), quality of health workers (X
7), use of mosquito coils (X8), use of topical insect repellent (X
9), and access of health workers (X
10). Maximum likelihood estimation is used to findout the parameter estimates. From the 10 predictor variables studied, it was found that only 8 variables had a significant effect on the model. Based on the odds ratio, the most significant variable is the quality of health workers with 16,5. The ability of predictor variables in explaining the response variable in the model is 87, 8%. The classification function in this study is 96, 3%.
Studies on Strength and Flexural Behaviour of Reinforced Concrete Beams with the Corroded Steel Reinforcements as a result of Sodium Chloride (NaCl)
Authors: Aswin M , Andres  , Gotami R 
Published: January 2023

Abstract
Corrosion on embedded reinforcement is a serious structural failure which its deterioration are rarely concerned. Reinforcing steel are frequently found left unattended on corrosive environment where potential corroding substances might expose surface of rebar resulting in corrosion initiation. This paper reports result of a study conducted to investigate the impact of a rebar corrosion on flexural strength of reinforced concrete beam induced by 10.5% NaCl. Tensile test was conducted in this study to determine the degradation of tensile strength on rebar and was later utilized to analyse the reduction of maximum load bearing capacity on reinforced concrete beam. Both flexural rebar and tensile rebar were corroded using manual basting method which is carried out every day from 08.00 A.M-10 P.M (every 2 hours step). The corrosion area on flexural steel samples is at the maximum flexural strength area (400 mm in the middle of the span) and is later used on flexural testing purposes after casting with concrete, the tensile steel samples which is 600 mm span of rebar is later utilized for tensile testing purposes and is corroded in the middle of the span (185 mm in the middle of the span). Based on test results, it was observed that steel bar suffered significant loss of weights due to corrosion induced by 10.5% NaCl with respect to its corroding duration three and four months are 1.85% and 3.34% reduction of weight from its normal form and its tensile strength degraded, respectively, 6.78 % and 9.86%. Meanwhile, the reinforced concrete beam with corroded steel bars happened to experience degradation of maximum load capacity which are, respectively, 10% and 15% reduction for three and 4 months of corroding duration.
Mapping the overlapping paratransit route in Medan City using GIS
Authors: Sembiring I S , Sukor N S A , Anas M R , Hastuti I P , Pandia I J 
Published: January 2023

Abstract
Paratransit is one of Public Transport in Medan City which operates in mixed traffic without a fixed schedule. This paper describes mapping of paratransit network services condition in Medan, Indonesia. Paratransit travel routes are analysed using a geographic information system that maps public transport routes. Analysis of GIS is used to explore paratransit routes, overlapping paratransit, paratransit services in terms of spatial planning. The results of the analysis can be used by the local transport authorities to improve the existing paratransit route. There is a lot of paratransit route overlapping, especially along Sisingamangaraja Road and Gatot Subroto Road, which is 19 paratransit along approximately 15 km.
Spatial distribution of 2019 forest and land fires in Indonesia
Authors: Thoha A S , Istima N , Daulay I A , Hulu D L N , Budi S , Ulfa M , Mardiyadi Z 
Published: January 2023

Abstract
Forest and land fires in 2019 were recorded as major events with extensive impacts on various aspects in Indonesia. An evaluation of forest and land fires in 2019 is required to determine the distribution and pattern of fires to be a significant input in overcoming forest and land fires in the future. This study aimed to evaluate forest fires based on area distribution, land cover, and area functions. This study used hotspot maps, land cover maps and forest area maps in 2019 to analyze the spatial distribution of locations and types of land cover that were indicated to be burning. The 2019 Landsat 8 OLI satellite images were used to identify types of land cover related to fires. We found that forest and land fires in 2019 in Indonesia were mostly spread on non-forest land with the type of land cover of shrubs, swamp shrub, and plantations with an area function for other use. The five provinces with the most fire hotspots detected were Central Kalimantan, West Kalimantan, Jambi, Riau, and South Sumatera. Most of the fire areas in the provinces that are vulnerable to fires are on peatlands. It requires serious and sustainable efforts to increase productivity and land value to reduce the area of unmanaged land and increase supervision of plantation companies that do not have an adequate forest and land fire management system.
Growth of Arengapinnata Seedlings on Three Different Media
Authors: Prakoso Budi , Widarawati R 
Published: January 2023

Abstract
Aren (Arengapinnata) trees are the second most important palm trees in Indonesia. However, little information on the effect of media on growth of aren (sugar palm) tree seedlings. The growth of six monts old seedlings on three media, namely soil, soil+Trichocompost, and sawdust+Trichocompost was studied. It was found that the growth of seedlings 45 days after replanting on soil+Trichocompost was higher than that of on sawdust+Trichocompost; However, the growth of the seedlings on soil media was not significantly lower than that of on soil+Trichocompost, nor significantly higher than that of on sawdust+Trichocompost.It was recommended that soil+Trichocompost and sawdust+Trichocompost can be used for aren seedling growing media.
Analysis of Organic Brown Sugar in Banyumas Regency
Authors: Putri Dindy Darmawati , Suyono S , Wijayanti Irene Kartika Eka 
Published: January 2023

Abstract
Banyumas Regency is one of the most potential organic brown sugar producers in Central Java. Organic brown sugar has a higher selling value than coconut sugar. The comparison of the price of coconut sugar and brown sugar which has a difference of Rp. 6,500.00 / kg with an average farmer production of 8 kg / day. The high price of brown sugar is very beneficial for coconut sugar farmers. This study aims to determine the income of the sugar craftsmen and determine the RC ratio. The research was conducted in two districts, namely Cilongok and Pekuncen districts, with 2 farmer groups, namely the Manggar Jaya farmer group and the Cikal Mas farmer group. The basic method used in this research is descriptive analysis. Data analysis using cost income analysis and RC ratio. The results showed that the craftsmen revenue Rp106,087.00 per day and the value of the RC ratio was 1.40 indicating that the business was feasible to run.