bluuebunny/crossref_metadata_2025_split huggingface dataset:
The power of the lens: Filming increases honesty in children as young as five
Authors: Sai Liyang , Bi Yue , Yu Chengfei , Ding Xiao Pan 
Published: August 2023

AbstractAs early as 5 years of age, children begin to manage their reputations strategically. We investigated whether the reputation concern elicited by filming affected children's mental cheating, which is a form of cheating that cannot be detected even if someone else is watching. During the test, the experimenter was in the room with children, and we operationalized reputational cues as whether the video camera was actively recording or not. We compared the self‐reported accuracy of a filmed group versus a non‐filmed group in a mental cheating game, under two motivational contexts: self‐interest and other‐interest. A total of 320 children aged 3 to 6 years played a mind game in which they were asked to predict the outcome of a dice roll and to report whether their prediction was correct. We found that 5‐ to 6‐year‐olds were less likely to cheat for their self‐interests when being filmed than when not being filmed. However, filming did not reduce 5‐ to 6‐year‐olds' other‐interested cheating. Furthermore, we found that filming did not influence the self‐interested or other‐interested cheating of 3‐ to 4‐year‐old children. This study highlights how reputation concern elicited by filming motivates children to appear honest to others, even in purely mental cheating scenarios. Additionally, our results suggest that young children are sophisticated in their early reputation management and that prosocial justifications can alleviate concerns about dishonesty.
Novel low‐temperature synthesis of Y2–xO3:Eux3+ nanophosphor using combustion with thioglycerol as fuel for near‐UV light‐emitting diodes
Authors: Patwardhan Milind A. , Jumale Jyotsna K. , Jumale Ritesh K. , Kohale Ritesh L. 
Published: August 2023

AbstractLuminescent materials used in flat panel displays, compact fluorescent lamps, and light‐emitting diodes require high purity, uniform particle size, clean surfaces, spherical shape, and dense morphology to ensure long‐term stability. Y2O3:Eu3+ is a widely studied red phosphor known for its characteristic photoluminescence (PL) emission at 613 nm with near‐UV excitation at 392 nm. Many methods have been explored to synthesize Y2O3:Eu3+ nanoparticles with exceptional purity, consistent phases, and uniform particle sizes. The aim is to synthesize particles with pristine surfaces, spherical shape, and compact morphology. This study focuses on the low‐temperature synthesis and PL investigation of Y2–xO3:Eux3+ nanophosphors using combustion with thioglycerol as fuel. The results are compared with Y2–xO3:Eux3+ red nanophosphors synthesized using wet chemical and nitrate combustion methods. The PL characteristics of the Y2–xO3:Eux3+ nanophosphors were analyzed using PL emission spectroscopy, X‐ray diffraction, and scanning electron microscopy. These findings highlight the advantageous properties of the synthesized nanophosphors, such as their suitability for solid‐state lighting applications in the lamp industry as highly efficient red phosphors. The combination of high purity, uniform particle size, clean surfaces, spherical shape, and dense morphology contributes to their potential for long‐term stability and reliable performance in lighting devices.
Advances in white light‐emitting organic crystals
Authors: Qiu Lin‐Qing , Lv Qiang , Wang Xue‐Dong 
Published: August 2023

AbstractIn past decades, organic crystals have presented considerable potential in the field of optoelectronics due to their rich tunable physical and chemical properties and excellent optoelectronic characteristics. White‐light emission, as a special application, has received widespread attention and has been applied in various fields, generating significant interest in the scientific community. By preparing white light‐emitting organic crystals, a series of applications for future white‐light sources can be realized. This article reviews the research progress on the molecular design and synthesis, preparation, and application of white light‐emitting organic crystals in recent years. We hope that this review will help to understand and facilitate the development of white light‐emitting organic crystals.
Recent advances in structure‐based enzyme engineering for functional reconstruction
Authors: Xu Shen‐Yuan , Zhou Lei , Xu Ying , Hong Han‐Yue , Dai Chen , Wang Ya‐Jun , Zheng Yu‐Guo 
Published: August 2023

AbstractStructural information can help engineer enzymes. Usually, specific amino acids in particular regions are targeted for functional reconstruction to enhance the catalytic performance, including activity, stereoselectivity, and thermostability. Appropriate selection of target sites is the key to structure‐based design, which requires elucidation of the structure–function relationships. Here, we summarize the mutations of residues in different specific regions, including active center, access tunnels, and flexible loops, on fine‐tuning the catalytic performance of enzymes, and discuss the effects of altering the local structural environment on the functions. In addition, we keep up with the recent progress of structure‐based approaches for enzyme engineering, aiming to provide some guidance on how to take advantage of the structural information.
Unraveling the potential and constraints associated with corn steep liquor as a nutrient source for industrial fermentations
Authors: Wahjudi Sekar Mayang W. , Petrzik Thomas , Oudenne Françoise , Lera Calvo Concepción , Büchs Jochen 
Published: August 2023

AbstractCostly complex media components such as yeast extract and peptone are still widely used in industrial bioprocesses, despite their ill‐defined composition. Side stream products such as corn steep liquor (CSL) present a compelling economical alternative that contains valuable nutrients required for microbial growth, that is, nitrogen and amino acids, but also vitamins, trace elements, and other minerals. However, as a side stream product, CSL may be subject to batch‐to‐batch variations and compositional heterogeneity. In this study, the Respiration Activity MOnitoring System designed for shake flasks (RAMOS) and 96‐well microtiter plates (μTOM) were applied to investigate the potential and constraints of CSL utilization for two model microorganisms: E. coli and B. subtilis. Considering the dry substance content of complex nutrients involved, CSL‐based media are more efficient in biomass production than the common lysogeny broth (LB) medium, containing 5 g/L yeast extract, 10 g/L peptone, and 5 g/L NaCl. At a glucose to CSL (glucose/CSL, g/g) ratio of 1/1 (g/g) and 2/1 (g/g), a secondary substrate limitation occurred in E. coli and B. subtilis cultivations, respectively. The study sheds light on differences in the metabolic activity of the two applied model organisms between varying CSL batches, which relate to CSL origin and production process, as well as the effect of targeted nutrient supplementation. Through a targeted nutrient supplementation, the most limiting component of the CSL‐glucose medium used for these applied model microorganisms was identified to be ammonium nitrogen. This study proves the suitability of CSL as an alternative nutrient source for E. coli and B. subtilis. The RAMOS and μTOM technique detected differences between CSL batches, allowing easy and early identification of varying batches. A consistent performance of the CSL batches in E. coli and B. subtilis cultivations was demonstrated.
A novel nomogram and risk classification system based on inflammatory and immune indicators for predicting prognosis of pancreatic cancer patients with liver metastases
Authors: Peng Linjia , Chen Hao 
Published: August 2023

AbstractBackgroundThe study determined to construct a novel predictive nomogram to access the prognosis of pancreatic cancer patients with liver metastases (PCLM).MethodsMedical records included clinical and laboratory variables were collected. The patients were randomly divided into training and validation cohort. First, in the training cohort, the optimal cutoff value of SII, PNI, NLR, PLR were obtained. Then the survival analysis evaluated the effects of above indices on OS. Next, univariate and multivariate analyses were used to identify the independent factors of OS. Moreover, a nomogram was constructed based on LASSO cox analysis. Additionally, the predictive efficacy of the nomogram was evaluated by ROC curve and calibration curve in the training and validation cohort. Finally, a risk stratification system based on the nomogram was performed.ResultsA total of 472 PCLM patients were enrolled in the study. The optimal cutoff values of SII, PNI, PLR and NLR were 372, 43.6, 285.7143 and 1.48, respectively. By combing SII and PNI, named coSII‐PNI, we divided the patients into three groups. The Kaplan–Meier curves demonstrated above indices were correlated with OS. Univariate and multivariate analyses found the independent prognostic factors of OS. Through LASSO cox analysis, coSII‐PNI, PNI, NLR, CA199, CEA, chemotherapy and gender were used to construct the nomogram. Lastly, the ROC curve and calibration curve demonstrated that the nomogram can predict prognosis of PCLM patients. Significant differences were observed between high and low groups.ConclusionsThe nomogram based on immune, inflammation, nutritional status and other clinical factors can accurately predict OS of PCLM patients.
Understanding users' switching intention of cloud storage services: A push‐pull‐mooring framework
Authors: Mohd‐Any Amrul Asraf , Sarker Moniruzzaman , Hui Fabian Low Zhen 
Published: August 2023

AbstractHighly sensitive and private information is stored in the cloud, so understanding how and why customers choose and switch between cloud storage service providers is pivotal. However, prior studies have tended to focus on users' adoption of cloud storage services, whereas little attention has been paid to their switching intention behavior based on non‐functional factors. Using the push‐pull model, developed from human migration theory, and by employing a survey (n = 326), we demonstrate that the push factor (i.e., satisfaction) has a significant negative effect, while the pull factor (i.e., alternative attractiveness) has a significant positive effect on users' switching intentions. Furthermore, mooring factors such as switching costs, habitual use, and past switching experiences have a varying moderation effect on the relationship between push and pull factors and switching intentions. The results offer several important theoretical and actionable managerial implications.
A Graphene Oxide‐Supported PdCu Catalyst for Enhanced Electrochemical Synthesis of Ammonia
Authors: Liang Zhuangzhuang , Cao Jianghui , Zhao Fang , Song Jiliang , Xue Sensen , Hua Qianqian , Ren Xuefeng , Gao Liguo , Ma Tingli , Liu Anmin 
Published: August 2023

AbstractThe conventional Haber‐Bosch method for the ammonia synthesis process requires high temperature and pressure. Electrochemical synthesis of ammonia, an emerging ammonia synthesis technology, is a promising approach for sustainable ammonia production that is energy‐efficient and free of greenhouse gas emissions. The design and development of high‐performance catalysts are the keys to promoting the sustainable ammonia production process. This work synthesized a PdCu alloy catalyst loaded on a graphene oxide carrier through a simple liquid phase reduction method. Which greatly enhanced the catalytic performance with an ammonia yield of 1.62 mg h−1cm−2 and Faradaic efficiency of 38.2 % under the nitrate reduction ammonia synthesis (NO3RR) reaction at an overpotential of −0.4 V. For the nitrogen reduction ammonia (NRR), the ammonia yield was 20.83 μg h−1 cm−2 with a Faradaic efficiency of 3.8 %. This study may provide a new idea for material design and promote ammonia synthesis development under ambient conditions.
Weakly Self‐Assembled [6]Helicenes: Circularly Polarized Light and Spin Filtering Properties
Authors: Rodríguez Rafael , Naranjo Cristina , Kumar Anil , Dhbaibi Kais , Matozzo Paola , Camerel Franck , Vanthuyne Nicolas , Gómez Rafael , Naaman Ron , Sánchez Luis , Crassous Jeanne 
Published: August 2023

AbstractSelf‐assembling features, chiroptical activity, and spin filtering properties are reported for 2,15‐ and 4,13‐disubstituted [6]helicenes decorated in their periphery with 3,4,5‐tris(dodecyloxy)‐N‐(4‐ethynylphenyl)benzamide moieties. The weak non‐covalent interaction between these units conditions the corresponding circularly polarized luminescence and spin polarization. The self‐assembly is overall weak for these [6]helicene derivatives that, despite the formation of H‐bonding interactions between the amide groups present in the peripheral moieties, shows very similar chiroptical properties both in the monomeric or aggregated states. This effect could be explained by considering the steric effect that these groups could generate in the growing of the corresponding aggregate formed. Importantly, the self‐assembling features also condition chiral induced spin selectivity (CISS effect), with experimental spin polarization (SP) values found between 35–40 % for both systems, as measured by magnetic‐conducting atomic force microscopy (AFM) technique.
Determination of carbon dioxide from a coke‐mentos‐fountain
Authors: Sommer Katrin , Thiele Doriano , Joch Philipp , Schäfer Alexander , Zellmer Stefan 
Published: August 2023

AbstractDie Cola‐mentos®‐Fontäne ist ein faszinierendes Showexperiment, bei dem durch Einwurf eines Kaubonbons in eine frisch geöffnete Cola‐Flasche eine Fontäne aus Kohlenstoffdioxid und mitgerissener Flüssigkeit entweicht. Es soll untersucht werden, ob das freiwerdende Kohlenstoffdioxid mit klassischen Fachmethoden quantifiziert werden kann. Dazu wird Coca‐Cola® light sowohl mittels pneumatischen Auffangens als auch durch gravimetrische Bestimmung des gefällten Carbonats untersucht. Die Methoden erweisen sich als zuverlässig. Der Vergleich verschiedener Cola‐Sorten unter Nutzung des pneumatischen Verfahrens offenbart, dass bei Coca‐Cola® light mehr Kohlenstoffdioxid freigesetzt wird als bei Coca‐Cola® classic.
Evaluating local thyroid cytopathology practices by molecular quality metrics: A multi‐institutional study on 4651 FNAs with a focus on the role of the interventional cytopathologist
Authors: Nacchio Mariantonia , Palladino Raffaele , Vigliar Elena , Pisapia Pasquale , Salatiello Maria , Malapelle Umberto , Porcelli Tommaso , Luongo Cristina , Fonderico Francesco , Masone Stefania , Salvatore Domenico , Troncone Giancarlo , Bellevicine Claudio 
Published: August 2023

AbstractBackgroundThe diagnostic accuracy of thyroid fine‐needle aspiration (FNA) can be highly influenced by the technical skills of the operator performing the procedure and by interobserver variability in microscopic interpretation. This is particularly true for the indeterminate categories. Recently, molecular testing has been proposed as an ancillary tool for monitoring the performance of different thyroid cytopathology practices. The objective of this multicenter study was to evaluate the quality of different local cytopathology practices by assessing the impact of interventional cytopathologists on FNA adequacy for molecular testing and the variations in mutation rates across different health care centers operating in the Campania region.MethodsThe study included 4651 thyroid FNA samples diagnosed in different Southern Italian clinical laboratories belonging to the TIRNET (the Tiroide Network). FNA samples were collected by different proceduralists and were classified by local cytopathologists according to The Bethesda System for Reporting Thyroid Cytopathology. FNAs classified as atypia of undetermined significance, follicular neoplasm, suspicious for malignancy, and malignant were centralized for a real‐time polymerase chain reaction‐based, seven‐gene test at the authors’ institution.ResultsCenters that employed interventional cytopathologists obtained fewer unsatisfactory FNA samples for molecular testing (11.3%) than centers that employed noncytopathologists (16.7%; p < .05). Furthermore, a significant variation in the mutation rate was observed in FNAs diagnosed by different local cytopathologists; indeterminate categories had the highest percentage of mutation rate variability among centers.ConclusionsInterventional cytopathologists obtained higher yields of diagnostic material for molecular testing. Finally, the current results suggest that the variability in mutation rates among different centers may highlight the low reproducibility of microscopic criteria among cytopathologists, particularly for indeterminate cases.
Photoresponsive Supramolecular Cages and Macrocycles
Authors: Nieland Esther , Voss Jona , Schmidt Bernd M. 
Published: August 2023

AbstractThe utilisation of light to achieve precise manipulation and control over the structure and function of supramolecular assemblies has emerged as a highly promising approach in the development of complex, configurable, or multifunctional systems and nanoscopic machine‐like entities. In this minireview, we highlight recent examples of self‐assembled and covalently bound cages and macrocycles with a focus on the external and internal functionalisation of a structure with a photoswitchable unit or the embedment of a photoswitch into the framework of a structure. Functionalising the interior or exterior of a supramolecular cage or macrocycle with a photoresponsive group enables control over different properties, such as guest binding or assembly in the solid‐state, while the overall shape of the assembly often undergoes no significant change. By directly integrating a photoswitchable unit into the framework of a supramolecular structure, the isomerisation can either induce a geometry change, the disassembly, or the disassembly and reassembly of the structure. Historical and recent examples covered in this review are based on azobenzene, diarylethene, stilbene photoswitches, or alkene motors that were incorporated into macrocycles and cages constructed by metal‐organic, dynamic covalent, or covalent bonds.
Comparative Study between 2‐Furonitrile and 2‐Cyanopyridine as Dehydrants in Direct Synthesis of Dialkyl Carbonates from CO2 and Alcohols over Cerium Oxide Catalyst
Authors: Sun Wen , Li Peilang , Yabushita Mizuho , Nakagawa Yoshinao , Wang Yuqi , Nakayama Akira , Tomishige Keiichi 
Published: August 2023

AbstractThe shift of equilibrium by removing water with nitrile dehydrants is crucial for CeO2‐catalyzed synthesis of dialkyl carbonates from CO2 and alcohols. Two nitriles – 2‐cyanopyridine and 2‐furonitrile – were previously found as effective dehydrants, yet their detailed comparison as well as exploration of potential of 2‐furonitrile remain insufficient. Herein, the performance of 2‐cyanopyridine and 2‐furonitrile was compared in the synthesis of various dialkyl carbonates. 2‐furonitrile was found to be superior to 2‐cyanopyridine in the synthesis of dialkyl carbonates from CO2 and bulky or long‐chain (≥C3) alcohols. Namely, the yield of diisopropyl carbonate (up to 50 %) achieved using CeO2 and 2‐furonitrile is comparable to or even higher than previously reported ones. Meanwhile, 2‐cyanopyridine acted as a better dehydrant than 2‐furonitrile in the synthesis of dimethyl carbonate and diethyl carbonate. The adsorption experiments and density functional theory calculations have indicated that the better performance of 2‐furonitrile compared to 2‐cyanopyridine in the synthesis of dialkyl carbonates from bulky or long‐chain alcohols is due to the weaker interaction of 2‐furonitrile with the CeO2 surface. Such weak interaction of 2‐furonitrile offers a larger reaction field on the catalyst surface for both CO2 and alcohols.
A unique cytotoxic CD4+ T cell‐signature defines critical COVID‐19
Authors: Baird Sarah , Ashley Caroline L , Marsh‐Wakefield Felix , Alca Sibel , Ashhurst Thomas M , Ferguson Angela L , Lukeman Hannah , Counoupas Claudio , Post Jeffrey J , Konecny Pamela , Bartlett Adam , Martinello Marianne , Bull Rowena A , Lloyd Andrew , Grey Alice , Hutchings Owen , Palendira Umaimainthan , Britton Warwick J , Steain Megan , Triccas James A 
Published: August 2023

AbstractObjectivesSARS‐CoV‐2 infection causes a spectrum of clinical disease presentation, ranging from asymptomatic to fatal. While neutralising antibody (NAb) responses correlate with protection against symptomatic and severe infection, the contribution of the T‐cell response to disease resolution or progression is still unclear. As newly emerging variants of concern have the capacity to partially escape NAb responses, defining the contribution of individual T‐cell subsets to disease outcome is imperative to inform the development of next‐generation COVID‐19 vaccines.MethodsImmunophenotyping of T‐cell responses in unvaccinated individuals was performed, representing the full spectrum of COVID‐19 clinical presentation. Computational and manual analyses were used to identify T‐cell populations associated with distinct disease states.ResultsCritical SARS‐CoV‐2 infection was characterised by an increase in activated and cytotoxic CD4+ lymphocytes (CTL). These CD4+ CTLs were largely absent in asymptomatic to severe disease states. In contrast, non‐critical COVID‐19 was associated with high frequencies of naïve T cells and lack of activation marker expression.ConclusionHighly activated and cytotoxic CD4+ T‐cell responses may contribute to cell‐mediated host tissue damage and progression of COVID‐19. Induction of these potentially detrimental T‐cell responses should be considered when developing and implementing effective COVID‐19 control strategies.
A case of endoscopic full‐thickness resection for gastric gastrointestinal stromal tumor in the submucosal tunnel
Authors: Shiwaku Hironari , Okada Hiroki , Shiwaku Akio , Kusaba Hiroshi , Maki Kenji , Shimaoka Hideki , Hashimoto Yasuhiro , Yamada Teppei , Yoshimura Fumihiro , Hasegawa Suguru 
Published: August 2023

AbstractThe patient was a 49‐year‐old female with a submucosal tumor (12×12 mm) located in the lesser curvature side of the stomach. The diagnosis by endoscopic ultrasound fine‐needle aspiration was of a gastrointestinal stromal tumor. Computed tomography and endoscopic ultrasound showed gastrointestinal stromal tumor with an intra‐luminal growth type. Endoscopic full‐thickness resection was then performed. To achieve good counter traction, enough safety margin, and minimal defect of muscle, full‐thickness resection via creating a submucosal tunnel was performed as a new technique. The final histological diagnosis was gastrointestinal stromal tumor with R0 resection.
Neural dependency in wound healing and regeneration
Authors: Noble Alexandra , Qubrosi Rozana , Cariba Solsa , Favaro Kayla , Payne Samantha L. 
Published: August 2023

AbstractIn response to injury, humans and many other mammals form a fibrous scar that lacks the structure and function of the original tissue, whereas other vertebrate species can spontaneously regenerate damaged tissues and structures. Peripheral nerves have been identified as essential mediators of wound healing and regeneration in both mammalian and nonmammalian systems, interacting with the milieu of cells and biochemical signals present in the post‐injury microenvironment. This review examines the diverse functions of peripheral nerves in tissue repair and regeneration, specifically during the processes of wound healing, blastema formation, and organ repair. We compare available evidence in mammalian and nonmammalian models, identifying critical nerve‐mediated mechanisms for regeneration and providing future perspectives toward integrating these mechanisms into a therapeutic framework to promote regeneration.