bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term beneficial impact of the randomised trial ‘Train the Brain’, a motor/cognitive intervention in mild cognitive impairment people: effects at the 14-month follow-up
Authors: Sale Alessandro , Noale Marianna , Cintoli Simona , Tognoni Gloria , Braschi Chiara , Berardi Nicoletta , Maggi Stefania , Maffei Lamberto ,   the Train the Brain Consortium, Maffei L , Picano E , Andreassi M G , Angelucci A , Baldacci F , Baroncelli L , Begenisic T , Bellinvia P F , Berardi N , Biagi L , Bonaccorsi J , Bonanni E , Bonuccelli U , Borghini A , Braschi C , Broccardi M , Bruno R M , Caleo M , Carlesi C , Carnicelli L , Cartoni G , Cecchetti L , Cenni M C , Ceravolo R , Chico L , Cintoli S , Cioni G , Coscia M , Costa M , D’Angelo G , D’Ascanio P , De Nes M , Del Turco S , Di Coscio E , Di Galante M , di Lascio N , Faita F , Falorni I , Faraguna U , Fenu A , Fortunato L , Franco R , Gargani L , Gargiulo R , Ghiadoni L , Giorgi F S , Iannarella R , Iofrida C , Kusmic C , Limongi F , Maestri M , Maffei M , Maggi S , Mainardi M , Mammana L , Marabotti A , Mariotti V , Melissari E , Mercuri A , Micera S , Molinaro S , Narducci R , Navarra T , Noale M , Pagni C , Palumbo S , Pasquariello R , Pellegrini S , Pietrini P , Pizzorusso T , Poli A , Pratali L , Retico A , Ricciardi E , Rota G , Sale A , Sbrana S , Scabia G , Scali M , Scelfo D , Sicari R , Siciliano G , Stea F , Taddei S , Tognoni G , Tonacci A , Tosetti M , Turchi S , Volpi L 
Published: May 2023

Abstract
No treatment options are currently available to counteract cognitive deficits and/or delay progression towards dementia in older people with mild cognitive impairment (MCI). The ‘Train the Brain’ programme is a combined motor and cognitive intervention previously shown to markedly improve cognitive functions in MCI individuals compared to non-trained MCI controls, as assessed at the end of the 7-month intervention. Here, we extended the previous analyses to include the long-term effects of the intervention and performed a data disaggregation by gender, education and age of the enrolled participants. We report that the beneficial impact on cognitive functions was preserved at the 14-month follow-up, with greater effects in low-educated compared to high-educated individuals, and in women than in men.
Development and validation of a standardized blood culture contamination definition and metric dashboard for a large health care system
Authors: Hancock Jill A , Campbell Sheldon , Jones Makoto M , Wang-Rodriguez Jessica ,   VHA Microbiology SME Workgroup, Klutts Stacey , Campbell Sheldon , Weber Theresa , Greene Bonnie , Espinosa Ruben Benitez , Orth Cari , Anderson Lyndi , Vigliotti Chasity , Frank Amy , Baraceros-Pineda Rosella , Donkle Jeanna , Cummings Tammy , Behrends Laura , Young Jennifer , Krajcir Shannon , Scholten Rachel , Klutts J Stacey 
Published: May 2023

Abstract

Objectives
Blood culture contamination is a major problem in health care, with significant impacts on both patient safety and cost. Initiatives to reduce blood culture contamination require a reliable, consistent metric to track the success of interventions. The objective of our project was to establish a standardized definition of blood culture contamination suitable for use in a Veterans Health Administration (VHA) national data query, then to validate this definition and query. A secondary objective was to construct a national VHA data dashboard to display the data from this query that could be used in VHA quality improvement projects aimed at reducing blood culture contamination.

Methods
A VHA microbiology expert work group was formed to generate a standardized definition and oversee the validation studies. The standardized definition was used to generate data for calendar year 2021 using a Structured Query Language data query. Twelve VHA hospital microbiology laboratories compared the data from the query against their own locally derived contamination data and recorded those data in a data collection worksheet that all sites used. Data were collated and presented to the work group.

Results
More than 50,000 blood culture accessions were in the validation data set, with more than 1,200 contamination events. The overall blood culture contamination rate for the 12 facilities participating was 2.56% with local definitions and data and 2.43% with the standardized definitions and data query. The main differences noted between the 2 data sets were deemed to be issues in local definitions. The query and definition were then converted into a national data dashboard that all VHA facilities can now access.

Conclusions
A standardized definition for blood culture contamination and a national data query were validated for enterprise-wide VHA use. To our knowledge, this represents the first reported standardized, validated, and automated approach for calculating and tracking blood culture contamination. This tool will be key in quality initiatives aimed at reducing contamination events in VHA.
And Where that Language Does Not Yet Exist
Authors: Stallings L H 
Published: May 2023

Abstract
This essay-review is centered on two recently published contemporary works about language, literature, embodiment, and ritual: Ana-Maurine Lara’s Queer Freedom: Black Sovereignty (2020) and Mecca Jamila Sullivan’s The Poetics of Difference: Queer Feminist Poetics in the African Diaspora (2021). Exploring creative and critical praxis as method and object of study, both authors provide innovative studies of queerness and queer worldmaking in the work of African diasporic spiritual and artistic communities.Lara’s and Sullivan’s arguments seem most relevant and timely for what twenty-first–century Black theorizing must do: refuse US exceptionalism, solidify transnational solidarities/relations across the African Diaspora, . . . better prepare for the abolition of gender.
Whites Aren’t Alright
Authors: Mitchell Jon 
Published: May 2023

Abstract
This essay evaluates how the three writers under review contribute to a persistent discussion about American identity and the many debates that still circulate around it—what it is and isn’t, and who it includes, fails to include, or shouldn’t include. Individually, each author tries to add nuance and contemporary problematics to the debates. Collectively, moreover, they remind the reader that, despite the work of identity politics in its many forms throughout the twentieth century and since; despite the increased secularization of the nation, or at least its culture; and despite even the election of a Black president or the presidential candidacy of a woman, these debates about race, gender, sexuality, and the place of religion in American life are just as significant now as they have ever been. Instead of seeing racism, sexism, homophobia, and religious fervor as remnants of the past or as legacies of beliefs that have been surpassed through progress, each book works to show how the fights over national identity are very much ongoing.“Despite how weathered this material has become . . . battles for equality are still pitched over the same ideas of a national sovereignty embedded in a frontier mentality that . . . sees the very work of inclusion and representation itself as the failure of the nation.”
146 Keynote: Jim Vincent and Inhalable Dust
Authors: Cherrie John 
Published: May 2023

Abstract
Jim Vincent was truly a modern-day Renaissance man. An accomplished jazz and classical pianist and composer, who performed with some of Europe's top improvisers, making appearances at major jazz festivals and in BBC broadcast concerts. However, his legacy lies elsewhere. He graduated in physics at the University of Durham with first-class honours in 1962, proceeding to a PhD in 1966. After jobs in academia and industry, in 1979 he became Head of Physics at the Institute of Occupational Medicine (IOM) in Edinburgh. He took over a research team that had been working on sampling of dusts for studies of the risks of lung disease in coal miners and other workers. Jim’s team defined the sampling criteria for the aerosol that can be inhaled into the nose or mouth, in collaboration with other European scientists and, in 1986, published the description and experimental characterisation of the IOM Inhalable Dust sampler. This sampler has been recommended for measuring dust exposure in workplaces around the world. Its design, which the IOM patented, has remained essentially unchanged for almost 40 years. Jim’s academic and professional achievements spanned an enormous breadth, but his legacy is his contribution to the way we sample hazardous aerosols.
91 Isocyanates Aerosols Sampling for Occupational Exposures Assessment
Authors: Guillemot Marianne , Ravera Christel , Melin Sandrine , Simon Xavier , Langlois Eddy 
Published: May 2023

Abstract
Isocyanate compounds are potent sensitizers, in particular through the development of skin dermatitis and allergies. They are one of the main causes of occupational asthma. None no-adverse-effect level has been establishes for isocyanates, therefore, it is important to measure isocyanates level at workplaces. Most of the time, isocyanates are present in workplaces atmosphere both in gas and particle phase, which makes their quantitative sampling difficult. Actual sampling methods do not fit with individual sampling over 8 hours. The aim of this work was first to characterize the particles size distribution in workplaces, depending on the isocyanate and the process used. Then, we studied the effectiveness of CIP 10-I as a sampling device for four isocyanates, compared to impinger and impregnated filter. Particles size distribution was determined thank to different cascade impactors such as Andersen, DLPI+ and MiniMOUDI-8. The Mass Median Aerodynamic Diameter (MMAD) of 4,4’-MDI (4,4’-diphenylmethane diisocyanate) particles in polyurethane foam projection process was found to be higher than 4 µm. In paint spray process, HDI (hexamethylene diisocyanate) particles MMAD was between 1 and 2 µm. The aerosol generation system was designed to obtain particles sizes closed to those observed in workplaces. The CIP 10-I collection foam was impregnated with the same derivative agent as filters. HDI, 2,4-TDI and 2,6-TDI (Toluene diisocyanate) aerosols were generating at concentrations between 10 and 250 µg/m3 in dry air. Whatever the concentration, CIP 10-I collection efficiency is higher than that of filters. Further investigation are currently performed to investigate CIP 10-I performance for MDI sampling.
108 Can Low-Cost Sensor Networks Help Occupational Hygiene?
Authors: Kangas Anneli , Winkler Nicholas P , Poikkimäki Mikko , Neumann Patrick P , Säämänen Arto 
Published: May 2023

Abstract
This study aims at achieving a better picture of the spatial and temporal distribution of industrial pollutants in the working environment. We explore the utilization of this information in occupational hygiene practice by developing and building a low-cost sensor network in multiple real working environments. Sensor networks were installed in different scenarios: in- and outdoors of a steel factory and on a cruise ship’s car deck. The stationary sensor networks are composed of multiple custom sensing nodes. Each node is equipped with various low-cost sensors to assess gaseous components, dust particles, temperature, and humidity. Additionally, measurements using validated traditional occupational hygiene methods and high end portable direct-reading instruments (DRIs) are performed stationary and mobile. Mobile devices carried by the workers in the breathing zone complement the measurements by the stationary sensor network. The results consist of evaluations carried out through combining the sensor data, contextual information and the results obtained with traditional occupational methods. Can this data fusion be used to assess exposure, and target risk management measures? In this work, we discuss the feasibility of the available sensors for industrial measurements and further explore the suitability of pollutant concentration maps for exposure assessment and for planning control measures.
129 A Novel Controlled Test Atmosphere Generation System for the Exposure Assessment Method Setup and Validation
Authors: Langlois Eddy , Schultz Benoit , Ravera Christel , Lily Jean Baptiste 
Published: May 2023

Abstract
Active sampling and analytical methods for the exposure assessment to chemical compounds have to be validated prior to be used on field. Requirements for the evaluation of these measuring procedures are specified in the ISO 22065 standard and include experiments to be done with a dynamic system for generating known concentration of gas and vapour in air under controlled conditions. Unfortunately, laboratories are rarely equipped with this kind of system and they have to carry out manual spiking of samples with a liquid micro-syringe, which is time consuming and source of uncertainty. In order to meet the requirements for accurate methods, we have designed and developed a fully automated generation system -called COMET generation system- that allows producing simultaneously four distinct concentration levels of gaseous pollutants and to perform automated multiple samples in each concentration branch according to the ISO 22065 standard compliance. The system is based on innovative pollutant generation, temperature and humidity control and multiple sampling technologies to be contained under a fume hood. The design of the system allows performing all the required sampling within a week whereas manual spiking need several weeks and excluding some important experiments where the temperature and the moisture have to be controlled. An online gas chromatograph or an Infrared photoacoustic analyzer determine the actual concentration in each concentration level branch. Two different methods were validated with both manual spiking and with the COMET system and the results were similar. Repeatability and overall uncertainty are significantly lower with the COMET system.
16 Advanced Solutions for Comprehensive Ambient Air Monitoring
Authors: Widdowson Caroline , Calder Hannah 
Published: May 2023

Abstract
Growing concerns over harmful exposure to low levels of hazardous air pollutants has led to increasingly demanding volatile organic compound (VOC) monitoring programs. Regulations are evolving to increase monitoring frequency, expand the list of target compounds and set lower detection limits in ambient air. Alongside this ambient and indoor air research continues to identify new, challenging compounds. There have long been specific standard methods and regulations for subsets of compounds, each using different instrumentation. For example method TO-15 for air toxics requires TD-GC-MS, ozone precursors monitoring uses TD-GC-FID and aldehydes are sampled with DNPH cartridges, analyzed by HPLC. Each compound set has its own challenges. Even so there is a drive to combine all three analyses into a single analytical run with the possibility of monitoring in online and offline. Additional considerations are high levels of humidity and large sample volumes, required to meet lower reporting limits. These require sophisticated trapping and water management techniques. As such removal of water from canister and on-line samples without loss of polar species is paramount for successful analysis of the Ozone Precursors, Air Toxics and oxygenated VOCs. This presentation will address the challenges associated with this complex compound list and show how confident identification and quantitation, with maximum sensitivity, can be achieved using state of the art pre-concentration technology. The cryogen-free methodology allows remote, on-line analysis or off-line canister sampling, all with a sample-to-sample cycle time of &lt;60 minutes, significantly reducing equipment overhead and analysis times whilst enhancing insight into air quality.
22 Evaluation of Occupational Exposure to Respirable Crystalline Silica in Processing of Artificial Stone
Authors: Salamon Fabiola , Martinelli Andrea , Gottardo Ottorino , Carrieri Mariella 
Published: May 2023

Abstract

Introduction
Clusters of silicosis cases related to the fabrication of quartz conglomerate products and accessories for the furnishing of kitchens and bathrooms are recently reported. The aim of this study was to evaluate the exposure to airborne respirable dust and crystalline silica (RCS) in a company specialized in the production of quartz conglomerates countertops and to investigate the effectiveness of introduced preventive measures (wet finishing, increasing of exhaust ventilation, closing in cabins some of the sanding and finishing operations).

Materials and Methods
The study was carried out on 51 workers involved in cutting and finishing operations in four facilities. Exposure to respirable dust was evaluated using GS3 cyclones positioned at the breathing zone level for the entire duration of the work shift. RCS content was measured by X-ray diffractometric analysis.

Results and Discussion
Respirable dust levels were in the range 0.046-1.154 mg/m3 (mean 0.160 mg/m3) with RCS levels within the range &lt;0.003-0.098 mg/m3 (mean 0.022 mg/m3). All RCS levels were lower than the Italian OEL of 0.100 mg/m3 and the 22% above the more restrictive ACGIH-TLV of 0.025 mg/m3. Statistically higher levels were found in correspondence with finishing operations than in cut operations (p&lt;0.05) and during dry operations than in wet (p=0.02). RCS levels were lower than those found in the past before the introduction of preventive technical measures where RCS levels were up to 0.744 mg/m3. Although there was a decisive reduction in exposure levels compared to what was observed in the past, the data still showed a risk condition for some activities. Board of the Italian Association of Industrial Hygienists (AIDII). Her scientific activity is documented by over 80 printed publications both as articles in Journals and contributions to National Congresses.
68 Urinary Biomarkers of Benzene Exposure and Oxidative Damage in Residents of the Oil Extraction Area of Muanda, Dr Congo
Authors: Radu - Corneliu Duca 
Published: May 2023

Abstract
The territory of Muanda, on the Atlantic coastline of the DR Congo, is an area of off-shore and on-shore oil extraction. Following concerns of the local population about the possible environmental and health consequences of these activities, a pilot study was performed in December 2015 to assess, among other issues, the exposure of residents of various relevant locations to oil-derived chemicals. We measured metabolites of benzene (t,t-Muconic Acid, MA, and S-Phenylmercapturic acid, S-PMA) by LC-MS and 8-hydroxy-2’-deoxyguanosine (8-OHdG, as an indicator of DNA damage) by ELISA, in urine spot samples of 53 volunteers (34 adults, 19 children, recruited by convenience sampling) living within areas of oil extraction with flaring (n=27), in an area where petroleum products were handled (n=14), and in a control area in the Mangroves National Park (n=12). Concentrations of both MA and S-PMA were increased among residents of the oil extraction areas (0.23±0.05 mg/L, 1.04±0.30 µg/L, respectively) and petroleum products area (0.32±0.08 mg/L, 1.74±0.63 µg/L, respectively) compared with controls (0.06±0.01 mg/L, 0.40±0.13 µg/L, respectively). Concentrations of of MA and S-PMA correlated with levels of 8-OHdG (RSpearman = 0.37, p&lt;0.01). Our biomonitoring study revealed a low degree of benzene exposure among residents living in the oil extraction and petroleum handling areas compared to a control area. Although the levels of benzene metabolites were low, the positive correlation with 8-OHdG possibly indicates that pollution by hydrocarbons induced oxidative damage in this study population.
70 Evaluation of High Efficiency Nebulisers to Increase the Sensitivity of the ICP-AES Technique Promulgated in ISO 15202
Authors: Butler Owen , Musgrove Darren 
Published: May 2023

Abstract
International Standard (ISO) 15202 describes methods for the determination of metals and metalloids in workplace air. Its development involved harnessing selected sample digestion procedures, promulgated in existing national standards, with additional method validation work carried out by HSE. In summary, requirements for air sampling (part 1); acid digestion procedures for dissolving air filter samples (part 2) and procedures for the analysis of digests (part 3) by inductively coupled plasma-atomic emission spectrometry (ICP-AES) are described. Exposure limit values for many metals/metalloids are now reducing and consequently more sensitive analytical techniques such as ICP-MS (promulgated in ISO 30011) may well be required in occupational hygiene laboratories. Boosting the sensitivity of the ICP-AES technique through the use of high efficiency sample introduction systems (nebulisers) is however possible as described in this presentation.
90 Bioaerosol Exposure in Automated and Traditional Waste Sorting Plants
Authors: Eriksen Elke , Afanou Anani Komlavi , Straumfors Anne , Graff Pål , Madsen Anne Mette 
Published: May 2023

Abstract
The waste management sector takes a central part in the transition towards circular economy and is subject to technological progress and the implementation of new work operations. Traditional waste collection and processing systems are characterized by numerous tasks that favour waste workers’ exposure to bioaerosols, whereas exposure in modern automated waste sorting plants remains elusive. Moreover, there is still a lack of health-risk based exposure limits for most components contained in bioaerosols. We investigated occupational exposure to bioaerosols in traditional and automated waste sorting plants. The results revealed significant differences in various exposure levels, such as total dust (GM automated: 0.34 mg/m3, GM manual: 0.66 mg/m3), endotoxins (GM automated: 51 EU/m3, GM manual: 32 EU/m3) and microorganisms between and within type of plant. An assessment of the composition of air-borne fungal particles (FESEM based immunodetection method) showed significantly increased levels of fungal spores at automated waste sorting plants (GM automated: 1.2 × 105 spores/m3, GM manual: 2.1 × 104 spores/m3). Elevated total dust levels and concentrations of submicronic fungal fragments were significantly correlated to the occurrence of symptoms of the extrathoracic region, such as congested nose, in exposed workers. The results of this study showed high variation in exposure levels between and within type of waste sorting plant, as well as seasonal variation for some parameters, such as total dust and endotoxins. This indicates that Norwegian waste workers are potentially exposed to high levels of dust and microorganisms that may cause adverse health effects in receptible individuals.
94 Reducing Exposure to Respirable Crystalline Silica in the Construction and Minerals Industry by Using Wearable Real Time Respirable Dust Monitors
Authors: Averdieck William , Furnell Linda 
Published: May 2023

Abstract
Real time monitoring of respirable dust (as a surrogate for RCS) opens the opportunity to warn workers when entering work areas with increased dust levels to provide them the information to fit RPE properly or exit the area. However in the past, the adoption of such monitoring approaches has been limited due to the bulkiness and price of devices. This paper reflects on how the miniaturisation of Optical Particle Counters has enabled light weight (&lt;150g) wearable devices to be developed which are convenient for workers in the construction and minerals industry to wear on all working days. It provides an overview of the Optical particle counter. its performance in measuring respirable dust and how it has been integrated into a battery powered ' DustCanary; wearable device. Due to its size and convenience the DustCanary provides protection to both those at first line risk due to the areas they work (eg stone cutters, plant operatives) who by wearing such can devices can help identify changes in performance of Local Exhaust Ventilation (LEV). or controls so that remedial action can be taken secondary risk on a plant who are not necessarily wearing RPE (such as delivery drivers) who can be warned when they enter an area where there are elevated respirable dust levels Case study data and examples will be shared.