bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel lithium-ion battery capacity prediction framework based on SVMD-AO-DELM
Authors: DING Guorong , Chen Hongxia 
Published: March 2023

Abstract
Accurate and efficient lithium-ion battery capacity prediction plays an important role in improving performance and ensuring safe operation. In this study, a novel lithium-ion battery capacity prediction model combining successive variational mode decomposition (SVMD) and aquila optimized deep extreme learning machine (AO-DELM) is proposed. Firstly, SVMD is used to divide capacity signal and it improves short-term trend prediction, especially for capacity growth that occurs during the degradation process. Secondly, the DELM network outperforms other networks in efficiently extracting time-dependent features, and it is more accurate than other standard ELM-based methods. The AO algorithm is used to optimize the parameters of the DELM training process for the problem of sensitivity to initial weights. Finally, experiments are conducted to validate the predictive performance of the proposed model based on NASA and CALCE lithium-ion batteries discharge capacity decay sequences. The MAE (0.0066Ah, 0.0044Ah), RMSE (0.0113Ah, 0.0078Ah), MAPE (0.44%, 0.82%) are effectively reduced and the R2 (98.94%, 99.87%) are better than the prediction performance of other hybrid models.
Core Patient-Reported Outcome Measures for Chronic Pain Patients treated with Spinal Cord Stimulation: Findings from a Prospective, Post-Market Study
Authors: Huygen Frank , Hagedorn Jonathan M. , Falowski Steven , Schultz David , Vesper Jan , Heros Robert D. , Patterson Denis G. , Mansouri Misagh , Ross Erika , Kyani Anahita , Kallewaard Jan Willem 
Published: March 2023

Abstract
Background

Spinal cord stimulation (SCS) is a highly effective therapy for treatment of chronic pain, however due to the complexity of pain, measuring a subject’s long-term response to the therapy remains difficult. Frequent measurement of patient-reported outcomes (PROs) to reflect multiple aspects of subjects’ pain is a crucial step in determining therapy outcomes. However, collecting full-length PROs is burdensome for both patients and clinicians. The objective of this work is to investigate the feasibility of using limited sets of outcomes from multiple PROs to accurately characterize subjects’ response to SCS therapy.

Methods

Validated PROs were used to capture pain, physical function and disability, as well as psychometric, satisfaction, and global health metrics. PROs were collected from 509 patients implanted with a neurostimulator enrolled in the post-market REALITY study. Combination of Pearson’s correlation and factor analysis was used to eliminate highly correlated questions and find the minimal meaningful set of questions within the predefined domains of each scale.

Results

The shortened versions of the questionnaires presented almost identical accuracy for classifying SCS therapy outcome as compared to the validated full-length versions. In addition, principal component analysis was performed on all the PROs and showed a robust clustering of pain intensity, psychological factors, physical function, and sleep across multiple PROs. A selected set of questions captured from multiple PROs can provide adequate information for measuring SCS therapy outcomes.

Conclusions

These shorter and more targeted PROs could result in better patient engagement, enhanced and more frequent data collection processes for digital health platforms, and ultimately increased patient satisfaction with SCS therapy.

Trial registration

Data for our analysis were extracted from the ongoing prospective, multicenter, international REALITY (Long-Term Real-World Outcomes Study on Patients Implanted with a Neurostimulator) study (NCT03876054).
Modulation of resting-state networks following repetitive transcranial alternating current stimulation of the dorsolateral prefrontal cortex
Authors: Khan Ahsan , Mosbacher Jochen A. , Vogel Stephan E. , Binder Mira , Wehovz Michael , Moshammer Arnulf , Halverscheid Stefan , Pustelnik Kolja , Nitsche Michael A. , Tong Raymond Kai-Yu , Grabner Roland H. 
Published: March 2023

Abstract
Transcranial alternating current stimulation (tACS) offers a unique method to temporarily manipulate the activity of the stimulated brain region in a frequency-dependent manner. However, it is not clear if repetitive modulation of ongoing oscillatory activity with tACS over multiple days can induce changes in resting-state functional connectivity. The current study addresses this question by applying multiple-session theta band stimulation on the left dorsolateral prefrontal cortex (L-DLPFC) during arithmetic training. Fifty healthy participants (25 males and 25 females) were randomly assigned to the experimental and sham groups, half of the participants received individually adjusted theta band tACS, and half received sham stimulation. Resting-state functional magnetic resonance (rs-fMRI) data were collected before and after three days of tACS-supported procedural learning training. Resting-state network analysis showed a significant increase in connectivity for the frontoparietal network (FPN) with the precuneus cortex. Seed-based analysis with a seed defined at the primary stimulation site showed an increase in connectivity with the precuneus cortex, posterior cingulate cortex (PCC), and lateral occipital cortex. We conclude that multi-session task-associated tACS can induce significant changes in resting state functional connectivity.
Prognostic analysis of traumatic spinal cord injury-related factors
Authors: He Shaojie , Zhao Zhenyu , Yu XinCheng , Kong Chang , Li Weikuan , Gu Haokun , Huang Weiguan , Ma Hangzhan , Zha Dingsheng 
Published: March 2023

Abstract
Background
To systematically analyze the evaluation indexes of injury degree and prognostic improvement in traumatic spinal cord injury.
Methods
A retrospective analysis of 133 patients with traumatic spinal cord injury admitted to our hospital from January 2017 to August 2021. The clinical indicators collected include the following: patient gender, age, underlying diseases, time from trauma to operation, length of hospital stay, intraoperative blood loss, cause of injury, whether accompanied with (or multi-segment ) spinal fracture and dislocation, intervertebral disc herniation, other sites of the injury and complications, the type of complications, spinal cord injury plane, surgical methods, ASIA grade within 72h and 6 months after injury, whether received hyperbaric oxygen therapy or high-dose cortisol hormone therapy, mean arterial pressure 3 days after operation, neutrophil/lymphocyte ratio (NLR) within 72h after admission, the length of MR spinal signal change, maximum canal compression (MCC), maximum spinal cord compression (MSCC), and the BASIC score of spinal signal changes.
Results
1) The length of signal change (p < 0.001), MSCC (p < 0.05), MCC (p < 0.05) and NLR within 72h of injury (p < 0.01) were significantly different among groups with different degrees of TSCI injury. 2) MAP (p༜0.01), NLR (p༜0.01), and the initial degree of injury (p༜0.05) showed significant differences between the groups of patients with improved and non-improved prognoses 6 months after TSCI injury.
Conclusions
The MRI signal change length, MSCC, MCC, and NLR within 72 h after injury are good indicators of the TSCI severity while MAP, NLR, and ASIA can be used to evaluate the prognosis of TSCI patients.
Aliasing Effect on Flux Ramp Demodulation: Nonlinearity in the Microwave SQUID Multiplexer
Authors: Salum J.M. , Muscheid T. , Fuster A. , Redondo M. Garcia , Hampel M.R. , Ferreyro L.P. , Geria J.M. , Bonilla-Neira J. , Müller N. , Bonaparte J. , Almela A. , Ardilla-Perez L.E. , Platino M. , Sander O. , Weber M. 
Published: March 2023

Abstract
A novel system formed by a Microwave Superconducting Quantum Interference Device (SQUID) Multiplexer (uMUX) and a room temperature electronics employs frequency division multiplexing (FDM) technique to read out multiple cryogenic detectors. Since the detector signal is embedded in the phase of the SQUID signal, a Digital Quadrature Demodulator (DQD) is widely implemented to recover it. However, the DQD also generates a signal that aliases into the first Nyquist zone affecting the demodulated detector signal. In this work, we demonstrate how this spurious signal is generated and a mathematical model of it is derived and validated. In addition, we discuss different proposals to improve the attenuation of this undesired signal. Lastly, we implement one of the proposals in our readout system. Our measurements show an enhancement in the spurious signal attenuation of more than 35 dB. As a result, this work contributes to attenuate the spurious below the system noise.
Laparoscopic cholecystectomy for xanthogranulomatous cholecystitis: 18 years of experience
Authors: Zubillaga-Mares Asya , Renteria-Palomo Enrique , Hall-Ramirez William Bryan , Lopez-Godinez Maria Fernanda , Nuñez-Venzor Alejandra , Cardenas-Lailson Eduardo 
Published: March 2023

Abstract
Introduction
Xanthogranulomatous cholecystitis (XGC) is a rare inflammatory disease of the gallbladder(GB). It has been classified as an uncommon variant of chronic cholecystitis with a prevalence of 0.7 to 10%. It is a difficult diagnosis because macroscopic appearance may be confused with gallbladder cancer (GC). Laparoscopic cholecystectomy is the gold standard for the management of benign gallbladder disease. Laparoscopic cholecystectomy in XGC is associated with a high conversion rate to open cholecystectomy with a rate of 10.6 to 80%.
Material and methods
A descriptive, observational, retrospective, and cross-sectional study was carried out over a period of 18 years at a general hospital on Mexico City. Patients with histopathological diagnosis of xanthogranulomatous cholecystitis were included. This study was retrospectively registered and approved by the board of ethical committee in our institution on 2018.
Results
We recorded 142 patients, and 106 surgeries were performed totally laparoscopically (74.6%). 52 were emergency surgeries (49%) and 54 elective (51%). The conversion rate to open cholecystectomy was 3.7% (4 patients). There were 5 post-surgical complications (4.7%) one biloma, one surgical site infection, and 3 pancreatitis.
Conclusions
XGX represents a surgical challenge from diagnosis to surgical management and is associated to a higher number of perioperative complications. Nevertheless, a laparoscopic approach is safe in high volume centers with experience in laparoscopy.
The influence of adding copper and iron third body on brake disc temperature
Authors: Yao Manqi , Zhao Chong , Su Linlin , Fu Rong , Han Xiaoming , Fei Gao 
Published: March 2023

Abstract
A large number of third bodies are born on the friction surface during braking. Exploring whether the third body has an impact on the friction surface temperature is helpful to recognize the wear factors affecting the brake disc. The effect of the third body composition on the temperature distribution of disc was studied by adding third body method on the TM-I inertial reduced scale brake testing machine, t Temperature distribution of the disc surface is compared at the pressure of 0.25 MPa and speed of 20–200 km/h under three conditions: no adding third body (NTB), adding Cu third body (CTB), and adding Fe third body (FTB). The results indicate that the difference in fluidity and thermal conductivity between CTB and FTB leads to the deviation of the contact state of surface, thus forming the variation of temperature and distribution state of brake disc. At a speed of 120–200 km/h, when adding the CTB, the maximum temperature of disc surface is reduced by 1.9–3.1%, the proportion of the high-temperature zone is reduced by 4.3–13.1%, and the unit width temperature of the high-temperature area decreases 2.2–3.2%. When adding the FTB, the maximum temperature of the disc surface rises by 4.1–7.4%, meanwhile, the proportion of the high-temperature area and the temperature per unit width are increased by 1.4–5.4% and 5.9–20.2%, respectively. At high speeds, the good fluidity and thermal conductivity of CTB lead to adhesive wear. FTB has high hardness, poor fluidity and thermal conductivity, which causes oxidative fatigue wear.
Whey-carrot based functional beverage: Development and storage study
Authors: Naik Bindu , Walter Nidhi , Kohli Deepika , Gupta Arun K , Mishra Sadhna , Khan Javed M. , Saris Per Erik Joakim , Irfan Mohammad , Rustagi Sarvesh , Kumar vijay 
Published: March 2023

Abstract

The current study was designed to prepare whey-carrot-based functional beverages and studying the effect on physicochemical properties during the 28 days of storage period. Different ratio of whey and carrot juice were selected for preparation of the six formulations, out of which based on the sensory acceptance only three were selected for the further storage studies (sample 1 = 45:55, sample 2 = 50:50, and sample 3 = 55:45 of carrot juice to whey ratio). During 28 days of storage, the developed beverage samples revealed a significant increase in reducing sugars, total phenolic content, and acidity. The pH, sweetness, and acceptance percentage of the beverage found to be decreased with storage period. It was also found that there is not change in the properties of the beverage storage with and without the preservative. It was revealed that beverage with less proportion of carrot juice is more acceptable quality. The results also suggest that whey can be used with fruit and vegetable to create whey-based beverage.
Liquid drops on compliant and non-compliant substrates: An ellipsoid-based fitting for approximating drop shape and volume
Authors: Haider Syed Ahsan , Raj Abhishek 
Published: March 2023

Abstract
We present a novel method of 3-dimensional surface fitting of a droplet using ellipsoids such that the droplet is a combination of segments of two to four distinct ellipsoids. Further, this fitting method has been used to develop an analytical model estimating the volume of a droplet resting over compliant as well as non-compliant substrate. Here, we have used Glass and Poly(methyl methacrylate) (PMMA) substrates as rigid, and, Polydimethylsiloxane (PDMS) free-hanging thin membranes (with thickness ranging from 20 − 40 𝜇𝑚) as compliant substrates. The analytical model considers the base length, width, height, and contact angles of the droplet captured from the experiment, and estimates the droplet volume. The proposed analytical model could predict the volume correctly for droplets resting over compliant as well as non-compliant substrates with a maximum deviation of 16.6 % for the volume range of 5 − 70 𝜇𝐿. Further, the predictions from the proposed analytical model are compared with the spherical cap-based model for droplets placed over compliant as well as non-compliant substrates. The spherical cap-based model failed to estimate the droplet volume over a compliant substrate with an error of > 50 %. Whereas, the proposed ellipsoid-based model could predict the droplet volume over compliant substrate correctly with a maximum error of 16.6 %. Also, the proposed analytical model predicts the volume of droplets even at high contact angle hysteresis (> 50𝑜) where the droplet has high radial asymmetry. Further, the study also illustrates how Artificial Neural Networks (ANNs) can be used to forecast droplet width and contact angle hysteresis (CAH). The droplet width predicted from ANN could be used to eliminate the requirement of measuring droplet width from the top view experimental image. The volume of the droplet can thus be predicted from its side profile alone when utilized in conjunction with the theoretical model. Further, we developed an ANN model which predicts the CAH of the droplet by considering the length scales of the droplet. The developed ANN models performed a very good prediction with an R-value of > 0.98.
Klotho enhances bone regenerative function of hPDLSCs via modulating immunoregulatory function and cell autophagy
Authors: Niu Qingru , Chen Huan , Ou Qianmin , Yang Shuqing , Peng Yingying , Xie Yunyi , Yu Le , Cheng Zhilan , Cao Yang , Wang Yan 
Published: March 2023

Abstract
Background：Human periodontal ligament stem cells (hPDLSCs) have a superior ability to promote the formation of new bones, and achieve tissue regeneration. However, mesenchymal stem cells (MSCs) are placed in harsh environments after transplantation, and the hostile microenvironment reduces their stemness and hinders their therapeutic effects. Klotho is an antiaging protein that participates in the regulation of stress resistance. In our previous study, we demonstrated the protective ability of Klotho in hPDLSCs.
Methods：A cranial bone defect model of rats was constructed and the hPDLSCs with or without Klotho pretreatment were transplanted into the defects. Histochemical staining and micro-computed tomography were used to detect cell survival, osteogenesis, and immunoregulatory effects of hPDLSCs after transplantation. The in vitro capacity of hPDLSCs was measured by a macrophage polarization test and the inflammatory level of macrophages. Furthermore, we explored autophagy activity in hPDLSCs, which may be affected by Klotho to regulate cell homeostasis.
Results：Pretreatment with the recombinant human Klotho protein improved cell survival after hPDLSC transplantation, and enhanced their ability to promote bone regeneration. Furthermore, Klotho pretreatment can promote stem cell immunomodulatory effects in macrophages and modulate cell autophagy activity, in vivo and in vitro.
Conclusion: These findings suggest that Klotho protein enhances the immunomodulatory ability of hPDLSCs and protects stem cells from stress after transplantation to maintain stem cell function by inhibiting cell autophagy.
Resistance of Anopheles stephensi to selected insecticides used for indoor residual spray and long-lasting insecticidal impregnated nets in Ethiopia
Authors: Teshome Abebe , Erko Berhanu , Golassa Lemu , Yohannes Gedeon , Irish Seth R. , Zohdy Sarah , Yoshimizu Melissa , Dugassa Sisay 
Published: March 2023

Abstract
Background: Malaria, transmitted by the bite of infective female Anopheles mosquitoes, remains a global public health problem. The presence of invasive Anopheles stephensi, capable of transmitting Plasmodium vivax and P. falciparum, was first reported in Ethiopia in 2016. The ecology of this mosquito species differs from that of An. arabiensis, the primary Ethiopian malaria vector [1]. This study aimed to evaluate the efficacy of selected insecticides, which are used in indoor residual spraying (IRS) and selected long-lasting insecticidal treated nets (LLINs) for malaria vector control, against adults An. stephensi.
Methods: Anopheles stephensi were collected as larvae and pupae from Awash Subah Kilo Town and Haro Adi village, Ethiopia. Adult female An. stephensi, reared from larvae and pupae collected from the field, aged 3-5 days were exposed to impregnated papers of IRS insecticides (propoxur 0.1%, bendiocarb 0.1%, pirimiphos-methyl 0.25%), and insecticides used in LLINs (alphacyper-methrin 0.05%, deltamethrin 0.05% and permethrin 0.75%), using diagnostic doses and WHO test tubes in a bio-secure insectary at Aklilu Lemma Institute of Pathobiology, Addis Ababa University (AAU-ALIPB). For each test and control tube, batches of 25 female An. stephensi mosquitoes were used to test each insecticide used in IRS. Additionally, cone tests were conducted to expose An. stephensi to four brands of LLINs, MAGNet™ (alpha-cypermethrin), PermaNet® 2.0 (deltamethrin), DuraNet© (alpha-cypermethrin) and SafeNet® (alpha-cypermethrin). A batch of ten sugar fed female mosquitoes aged 2-5 days were exposed to samples taken from five positions/sides of a net. The data from all replicates were pooled and descriptive statistics were used to describe features of the data.
Results: All An. stephensi mosquitoes collected from Awash Subah Kilo Town and Haro Adi village (around Metehara) were resistant to all tested insecticides used in both IRS and LLINs. Of the tested LLINs, only MAGNet™ (alpha-cypermethrin active ingredient) caused 100% knockdown and mortality to An. stephensi at 60 minutes and 24 hours post exposure, while all other net brands resulted below the WHO cut- off points. All these nets, except SafeNet®, were collected during LLIN distribution for community members through the National Malaria Program, in December 2020.
Conclusions: Anopheles stephensi is resistant to all tested insecticides used in IRS and in the tested LLIN brands, except MAGNet, did not cause in mortality as expected. This suggests that control of this invasive vector using existing adult malaria vector control methods may not be appropriate and that alternative strategies may be necessary.
Design of Biosensor Based on Graphene Oxide/ WO3/ Polyvinylidene Fluoride
Authors: Sobhy Manar , Khafagy Rasha M. , Soliman Aisha A. , Ibrahim Medhat A. 
Published: March 2023

Abstract
As significant efforts are invested in improving glucose smart biosensors, hyperglycemia (high blood glucose) is poised to be one of the most serious healthcare concerns in the coming decades. Accordingly, a graphene-based hybrid nanocomposite of graphene oxide (GO)/ tungsten oxide (WO3)/polyvinylidene fluoride (PVDF) for glucose sensing was designed. Density functional theory (DFT) at the B3LYP/LanL2DZ level of theory was used to optimize the proposed structures. To show the findings, the total dipole moment (TDM), HOMO/LUMO band gap energy (ΔE), and molecular electrostatic potential (MESP) were investigated. The results show that the model molecule representing GO interacted with WO3 throughout the carboxyl group (COOH) and possess the highest TDM of 5.6912 Debye and lowest ΔE of 0.0155eV. Additionally, the incorporation of PVDF into the GO/WO3 model molecule reduces the TDM to 13.2549 Debye and ΔE to 0.0105 eV. Moreover, MESP shows that the interaction of PVDF with the GO/ WO3 model molecule increases the reactivity of GO/ WO3 molecule. The adsorption of the glucose molecule to the GO/ WO3/PVDF model enhances the reactivity of the GO/WO3/PVDF molecule as TDM increases to 20.5130 Debye and ΔE increases slightly to 0.0120 eV. Because of their low synthesis costs, GO, WO3, and PVDF-based biosensors are good candidates for glucose sensing.