bluuebunny/crossref_metadata_2025_split huggingface dataset:
Juridical Analysis of Confiscation of Looted Goods and State Seizures in Corruption Crimes
Authors: Kaluku Nur Kevin 
Published: August 2023

Abstract:The act of confiscation of goods resulting from criminal acts of corruption is not easy and faces various obstacles in its implementation. The existence of confiscated and confiscated objects that have expensive maintenance costs has actually become a new burden for the government and has the potential to pose a big risk in the future. The purpose of this research is to examine the procedures for confiscation of confiscated goods and state confiscations in corruption crimes as well as to formulate efforts that will optimize the regulation of confiscated goods and state confiscations resulting from criminal acts of corruption. This research is a normative research using a law approach, a case approach, and a conceptual approach in the research approach. The results of the study indicate that the existing problem is that the procedure for confiscation of confiscated goods and state confiscations resulting from criminal acts of corruption is carried out and involves various agencies, namely the Attorney General's Office, the Corruption Eradication Commission (KPK), the Ministry and Rupbasan in accordance with the legislation that has been set. However, in practice there are various obstacles that must be improved and minimized by the various agencies. With regard to confiscated and confiscated goods, criminal acts of corruption use the in personam principle Keywords: Corruption, Confiscation, Looted Goods
Guarantee of legal trade against wages at PT. Gorontalo Citra Lestari
Authors: TOI SITI MAGFIRA 
Published: August 2023

This research aims to find out how The Legal Protection of Workers' Wages in PT. Gorontalo Citrea Lestari. The type of research used in this paper is empirical research. This research uses a case approach, by conducting a review of cases related to the issues faced that have become court decisions that have had permanent powers. The results of this study show the Legal Protection of Workers' Wages in PT. Gorontalo Citra Lestari has not fully run optimally, this is proven by the violation of the law felt by workers. Preferably pt. Gorontalo Citra Lestari is more concerned with the protection of its workers by labor laws, and the protection of workers must be implemented to the maximum this creates a sense of security and comfort towards workers and does not cause things that are not desirable.
Legal Efforts To Protect Franchisees Against Termination Of Employment Agreements
Authors: Chaerunisa Nur Ifani 
Published: August 2023

The purpose of this study is to find out the legal efforts to protect franchisees against termination of employment agreements. The research method used is the dualism of normative-empirical legal research whereby research uses normative-empirical legal case studies in the form of legal behavioral products. The approach used is a juridical approach and analytical technique using qualitative analytical methods. The results showed that the form of legal protection against franchisees in agreements with franchisees is contained in the Regulation of the Minister of Trade Number: 12/MDAG/Per/3/2006, in Article 7 that the term of the franchise agreement (franchising) is valid for at least 5 years. These terms provide legal protection to the franchisor as the franchisor, as such the franchisor cannot terminate the agreement at any time or at any time. It is necessary to immediately regulate regulations that directly or indirectly concern franchise business practices made in the form of legislation, such as the Antitrust or Antitrust Act and the current Business Competition Act.
The Legal Position Of The Will Given To The Adopted Child As Proof Of Ownership In The Gorontalo Religious Court
Authors: Hinelo Meriyani 
Published: August 2023

Abstract: The purpose of this study is to find out and analyze the Juridical Analysis of Religious Court Decision Number: 403/PDT. G/2019/PA. Gtlo Concerning the Determination of Probate Disputes and the Legal Position of the Will as proof of rights in the judgment of the Judge. Research Uses this type of normative-empirical research. Using several approaches, namely:the legal approach(statue approach), the case approach (case approach). The results of this study show that: First, that based on juridical analysis of religious court decision number: 403/PDT. G/2019/PA. Gtlo About the Determination of Will Disputes has been in line with the provisions of the event law, where the first condition that must be met by the plaintiff is regarding material conditions, while the plaintiff in his lawsuit is wrong in occupying defendant 1 and defendant 2 (two). Second, that the legal position of the Will as proof of rights in the judge's consideration is not used as a balance material by pa judges because there are defects as intended by the researcher, therefore the judge ruled the lawsuit is unacceptable(Niet Onvantkelijke Verklaard) ) which means that the case has not been completed with a positive verdict in the sense that it has not touched the subject matter and if the plaintiff wants to re-apply must complete the terms of the formil in questionKeywords: Position; Will; Dispute
Law Enforcement Against Minors as Narcotics Dealers in Pohuwato Regency
Authors: Ishak Mohammad 
Published: August 2023

Abstract: This study aims to analyze law enforcement against minors as narcotics traffickers in Pohuwato Regency. The process of law enforcement on children uses a different application method from other legal models. because the suspect who is brought before the investigator's desk is a person who is still underage or not yet legally competent. Based on this, the researcher aims to analyze the application of law to minors as narcotics traffickers. This study uses an empirical method by including interview data along with official data sourced from the Indonesian National Police, especially the Pohuwato Regional Police. justice and balance for the perpetrators of the crime and the victims themselves. Factors that become obstacles in the application of the law against narcotics committed by minors are divided into two, namely internal factors and external factors. With the diversion method based on a justice or judicial approach based on deliberation or restorative justice , it is hoped that legal development in Indonesia will prioritize more humanistic laws so that Indonesian law does not seem rigid. Keywords: Diversion, Narcotics, Restorative Justice
Electronic Legality Of Employment Contracts On Minor Children
Authors: Nusi Novriyanto 
Published: August 2023

Based on the results of the study, the answers to the existing problems were obtained, that the validity of the employment contract between Youtube and the content creator who was still underage in the statutory provisions contained four conditions for the validity of an agreement, one of which involved the ability to make agreements. Like the real world, there are several requirements from the electronic service provider that must be approved by social media users, especially a content creator. These requirements are commonly known as terms of service. One of the things that are usually regulated in the terms of service is the age of the user so that the legal relationship that exists between the child and the agency or institution is based on the existence of a working relationship between the two parties, in which the child can be represented by the parent or guardian based on a work agreement because children are still unable to carry out legal actions independently, this is because children are categorized as people who are not yet capable of carrying out legal actions As for government regulations regarding employment contracts between YouTube and content creators who are still underage, it can be seen in several laws and regulations in Indonesia which regulate the procedures for engagements or work contracts such as the Civil Code, the ITE Law and in the Manpower Act. For example, in the Civil Code, one of the things that can be used as a reference in the validity of a contract is age, namely 21 years or already married, so based on the problem formulation, the researcher gives an idea in the form of underage content creators who are required to be accompanied or represented by parents or guardians in entering into agreements or contracts with the youtube platform service provider so that it cannot damage the validity of the contract or agreement that has been made by the parties.Keywords: Validity of Employment Contract, Content Creator Children.
The Effectiveness Of The National Land Agency In Implementing The Complete Systemic Land Registration Program
Authors: Mootalu Sri Rahayu 
Published: August 2023

The research aims to determine to what extent the role of Nasional Land Agency in implementing the complete and systematic Land Registration (PTSL) program and internal and external factors inhibiting the National Land Agency in implementing the Complate and Systematic Land Registration (PTSL) program towards the improvement of Land Certificate Ownership Data in Gorontalo Regency. In this case, the program has been done well, yet it remains encountering several problems. The research employs empirical legal research. The problems in this current research are the role of National Land Agency in implementing the Complate and Systematic Land Registration (PTSL) program towards the impprovment of Land Certificate Ownership Data in Gorontalo Regency and internal and external factors inhibiting the implementation of program. The research finding reveals that the implementation of Complete and Systematic Land Registration (PTSL) program by National Land Agency remains not maximum. Therefore, it is necessary to fiind a preper solition so that the PTSL program could achieve the predetermined target and implementation stages must be in accordance with the prevailing regulation. Keywords: Role of BPN, PTSL Program, Land Certificate Ownership
Legal Analysis of The Privacy of State-Owned Enterprises
Authors: Fauzi Ahmad 
Published: August 2023

The world's market economic system influences the management behavior of State-Owned Enterprises which has been lulled by the monopolistic system. The market economic system requires the community as the main actor and the state as the facilitator. Competition occurs in companies as well as in State-Owned Enterprises. To increase efficiency and productivity, must make changes to the management system by making structural adjustments which have been known as restructuring. The government formulates the direction of targets and policies for the management and supervision of State-Owned Enterprises Law Number 19 of 2003 concerning State-Owned Enterprises was made to fulfill the vision of future development; create a management and supervision system based on the principles of efficiency and productivity to improve performance and value in managing and confirming the role of government institutions and the position of government representatives as shareholders or capital owners to emphasize and clarify the relationship as an operator or business actor with a government institution as a regulator; to avoid acts of exploitation outside the corporate mechanism; to lay the foundations or principles of good corporate governance (Good Corporate Governance). The aim is to regulate operations, regulate restructuring, and privatization as a tool and method in State-Owned Enterprises.
The Principle of Freedom of Contract in Agricultural Product Sharing based on Islamic Law
Authors: Bakung Dolot Alhasni , Abdussamad Zamroni , Muhtar Mohamad Hidayat 
Published: August 2023

Islamic financial scheme in practice is still causing problems in the wider community due to differences in perceptions that exist in the community. The principle of freedom of contract in Law No. 2 of 1960 concerning agricultural product sharing and Islamic law, especially related to agricultural product sharing and Article 1338 paragraph (1) of the civil code which stipulates that a legally made Agreement will apply like a law for the maker (Pacta Sunt Servanda principle), the word “all” means that every legal subject can make an agreement whose contents are about anything, legal subjects have the freedom to determine the form of the agreement. This normative research aims to analyse the legal ramifications of violating the concept of freedom of contract in agricultural product sharing from the viewpoints of Islamic law. This result of this article found that the implementing of the revenue sharing system did not get a fair share, this was because at the time of the contract, farmers were in a weak position due to the need for money for children's education and other emergency needs, especially during the Covid-19 pandemic. The owner of the land has the right to obtain part of the crop on the farm managed by the cultivator and receive back the return of the land upon completion of the agreement.
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury
Authors: Xiao Yu , Hu Xinmei , Jiang Peng , Qi Zhongquan 
Published: August 2023

Introduction: Spinal cord injury (SCI) is a serious and disabling condition, and the effectiveness of conventional treatment is limited, such as supportive treatment and emergency surgery. Exosomes derived from umbilical cord mesenchymal stem cells (UCMSC-Exos) have potential therapeutic effects on SCI but are limited by delivery efficiency. Our study aimed to further investigate the therapeutic effects of miR-138-modified UCMSC-exosomes (Exos-138) following SCI.Methods: We developed an injectable triblock polymer of polyglycolic acid copolymer and polyethylene glycol (PLGA-PEG-PLGA)-loaded temperature-sensitive hydrogel of miR-138-modified stem cell exosomes and characterised its biocompatibility in vitro. In Sprague-Dawley rats with SCI, the hydrogel was injected into the injury site, behavioural scores were measured, and pathological analysis was conducted postoperatively to assess neurological recovery.Results:In vitro, our data demonstrated that miR-138-5p-modified UCMSC-Exos can reduce inflammation levels in BV-2 cells through the NLRP3-caspase1 signalling pathway and reduce neuronal apoptosis by downregulating intracellular reactive oxygen species levels through the Nrf2-keap1 signalling cascade. The results of in vivo experiments showed that the P-Exos-138 hydrogel promoted neurological recovery in rats with SCI.Discussion: Our study explored a novel exosome delivery system that can be a potential therapeutic strategy for SCI. Our study, currently, has theoretical value; however, it can serve as a basis for further investigations on the treatment approaches at various stages of SCI development in inflammation-dependent injury of the central nervous system.
Case report: The presence of third-degree atrioventricular block caused by pulmonary embolism masquerading as acute ST-segment elevation myocardial infarction
Authors: Ma Min , Liang Shichu , He Yong , Wang Hua 
Published: August 2023

BackgroundPulmonary embolism (PE) typically presents with chest pain, tachypnea, hemoptysis, syncope, and increased markers of myocardial injury. On an electrocardiogram (ECG), sinus tachycardia, right bundle branch block (RBBB), S1Q3T3 pattern, and/or precordial T-wave inversion may be observed. Despite being one of the common causes of chest pain, a third-degree atrioventricular block (III° AVB) is rare in cases of PE, which can lead to difficulties in diagnosis or even overlooking this condition.Case summaryIn this case report, we present a patient who was transferred to our hospital with suspected acute myocardial infarction (AMI). The patient's ECG showed ST-segment elevation in the inferior wall and a III° AVB, combined with significantly increased markers of myocardial injury. Interestingly, the patient also had a history of cerebral hemorrhage (ICH) for 7 days prior to being transferred to our hospital. After undergoing a systematic examination and evaluation, the final diagnosis for the patient was PE.ConclusionsIn addition to considering common symptoms, it is important not to overlook rare symptoms when diagnosing a disease. This case serves as an example of how the misdiagnosis rate for PE can be reduced by conducting a comprehensive clinical evaluation and paying attention to all clinical clues and examination results.
Nordcan.R: a new tool for federated analysis and quality assurance of cancer registry data
Authors: Larønningen Siri , Skog Anna , Engholm Gerda , Ferlay Jacques , Johannesen Tom Børge , Kristiansen Marnar Fríðheim , Knoors Daan , Kønig Simon Mathis , Olafsdottir Elinborg J. , Pejicic Sasha , Pettersson David , Skovlund Charlotte Wessel , Storm Hans H. , Tian Huidong , Aagnes Bjarte , Miettinen Joonas 
Published: August 2023

Aim of the articleWe present our new GDPR-compliant federated analysis programme (nordcan.R), how it is used to compute statistics for the Nordic cancer statistics web platform NORDCAN, and demonstrate that it works also with non-Nordic data.Materials and methodsWe chose R and Stata programming languages for writing nordcan.R. Additionally, the internationally used CRG Tools programme by International Agency for Research on Cancer (IARC/WHO) was employed. A formal assessment of (GDPR-compliant) anonymity of all nordcan.R outputs was performed. In order to demonstrate that nordcan.R also works with non-Nordic data, we used data from the Netherlands Cancer Registry.Resultsnordcan.R, publicly available on Github, takes as input cancer and general population data and produces tables of statistics. Each NORDCAN participant runs nordcan.R locally and delivers its results to IARC for publication. According to our anonymity assessment the data can be shared with international organizations, including IARC. nordcan.R incidence results on Norwegian and Dutch data are highly similar to those produced by two other independent methods.Conclusionnordcan.R produces accurate cancer statistics where all personal and sensitive data are kept within each cancer registry. In the age of strict data protection policies, we have shown that international collaboration in cancer registry research and statistics reporting is achievable with the federated analysis approach. Undertakings similar to NORDCAN should consider using nordcan.R.
The genetic variant rs55986091 HLA-DQB1 is associated with a protective effect against cervical cancer
Authors: Vinokurov Michael A. , Mironov Konstantin O. , Domonova Elvira A. , Romanyuk Tatiana N. , Popova Anna A. , Akimkin Vasiliy G. 
Published: August 2023

IntroductionCervical cancer (CC) is a prevalent malignancy affecting women globally. The primary causative factor of CC is the high-risk oncogenic human papillomavirus (HR-HPV). However, it is noteworthy that not all women infected with HR-HPV develop cancer, indicating the potential involvement of genetic predisposition in the development of CC. This study aims to identify genetic risks and their distribution in groups of women with different epidemiological features of HR-HPV.Materials and methodsA comparison was conducted among four groups of women, comprising 218 HPV-negative women, 120 HPV-positive women, 191 women diagnosed with cervical intraepithelial neoplasia (CIN) grade 2 or 3, and 124 women diagnosed with CC. The analysis focused on four single nucleotide polymorphisms (SNPs): rs55986091 in HLA-DQB1, rs138446575 in TTC34, rs1048943 in CYP1A1, and rs2910164 in miRNA-146a.ResultsThe rs55986091-A allele exhibited a protective effect within the “CC” group when compared to the “HPV-Negative” group (OR = 0.4, 95% CI= 0.25-0.65) using a log-additive model. Additionally, similar protective effects were observed in the “CIN 2/3” group compared to the “HPV-Negative” group (OR = 0.47, 95% CI = 0.28-0.79).ConclusionThe data obtained emphasize the importance of developing PCR-based diagnostic kits for the identification of SNP alleles, particularly for rs55986091, among HR-HPV-positive women within the Russian population.
Multi-organ spatial stratification of 3-D dose distributions improves risk prediction of long-term self-reported severe symptoms in oropharyngeal cancer patients receiving radiotherapy: development of a pre-treatment decision support tool
Authors: Wentzel Andrew , Mohamed Abdallah S. R. , Naser Mohamed A. , van Dijk Lisanne V. , Hutcheson Katherine , Moreno Amy M. , Fuller Clifton D. , Canahuate Guadalupe , Marai G. Elisabeta 
Published: August 2023

PurposeIdentify Oropharyngeal cancer (OPC) patients at high-risk of developing long-term severe radiation-associated symptoms using dose volume histograms for organs-at-risk, via unsupervised clustering.Material and methodsAll patients were treated using radiation therapy for OPC. Dose-volume histograms of organs-at-risk were extracted from patients’ treatment plans. Symptom ratings were collected via the MD Anderson Symptom Inventory (MDASI) given weekly during, and 6 months post-treatment. Drymouth, trouble swallowing, mucus, and vocal dysfunction were selected for analysis in this study. Patient stratifications were obtained by applying Bayesian Mixture Models with three components to patient’s dose histograms for relevant organs. The clusters with the highest total mean doses were translated into dose thresholds using rule mining. Patient stratifications were compared against Tumor staging information using multivariate likelihood ratio tests. Model performance for prediction of moderate/severe symptoms at 6 months was compared against normal tissue complication probability (NTCP) models using cross-validation.ResultsA total of 349 patients were included for long-term symptom prediction. High-risk clusters were significantly correlated with outcomes for severe late drymouth (p &lt;.0001, OR = 2.94), swallow (p = .002, OR = 5.13), mucus (p = .001, OR = 3.18), and voice (p = .009, OR = 8.99). Simplified clusters were also correlated with late severe symptoms for drymouth (p &lt;.001, OR = 2.77), swallow (p = .01, OR = 3.63), mucus (p = .01, OR = 2.37), and voice (p &lt;.001, OR = 19.75). Proposed cluster stratifications show better performance than NTCP models for severe drymouth (AUC.598 vs.559, MCC.143 vs.062), swallow (AUC.631 vs.561, MCC.20 vs -.030), mucus (AUC.596 vs.492, MCC.164 vs -.041), and voice (AUC.681 vs.555, MCC.181 vs -.019). Simplified dose thresholds also show better performance than baseline models for predicting late severe ratings for all symptoms.ConclusionOur results show that leveraging the 3-D dose histograms from radiation therapy plan improves stratification of patients according to their risk of experiencing long-term severe radiation associated symptoms, beyond existing NTPC models. Our rule-based method can approximate our stratifications with minimal loss of accuracy and can proactively identify risk factors for radiation-associated toxicity.