bluuebunny/crossref_metadata_2025_split huggingface dataset:
«Sup en Poche»
Authors: Coulaud Jean-Baptiste , Guillaume Anne-Marie , Bertrand Émilie , Genette Anne 
Published: February 2023

Analyse critique de :
Cottet-Émard (François), Toutes les maths pour bien commencer sa licence. – Louvain-la-Neuve : De Boeck Supérieur, 2017. – v, 249 p. – (Sup en poche). – 1 vol. broché de 15 × 21 cm. – 16,00 €. – isbn 978-2-8073-1012-4.
Villain (Loïc), Mécanique du point. – Louvain-la-Neuve : De Boeck Supérieur, 2017. – vi, 249 p. – (Sup en poche). – 1 vol. broché de 15 × 21 cm. – 16,00 €. – isbn 978-2-8073-0766-7.
Taillet (Richard), Optique géométrique. – Louvain-la-Neuve : De Boeck Supérieur, 2017. – viii, 245 p. – (Sup en poche). – 1 vol. broché de 15 × 21 cm. – 16,00 €. – isbn 978-2-8073-0764-3.
Baggio (Stéphanie) - Rothen (Stéphane) - Deline (Stéphane), Statistique descriptive. – Louvain-la-Neuve : De Boeck Supérieur, 2017. – 220 p. – (Sup en poche). – 1 vol. broché de 15 × 21 cm. – 16,00 €. – isbn 978-2-8073-1491-7.
musiciens, la maladie et la médecine
Authors: Caspar Philippe 
Published: February 2023

Analyse critique de :
Pinet (Patrice), Les musiciens, la maladie et la médecine de Guillaume de Machaut à Béla Bartók. – Paris : L’Harmattan, 2017. – 409 p. – (Médecine à travers les siècles). – 1 vol. broché de 15,5 × 24 cm. – 39,00 €. – isbn 978-2-343-13073-6.
Compte rendu de Marie-Chantal Morel-Bracq (sous la direction de) : «Les modèles conceptuels en ergothérapie : introduction aux concepts fondamentaux»
Authors: Terrana Gwendoline , Terrier Florence 
Published: February 2023

Les modèles conceptuels en ergothérapie : introduction aux concepts fondamentaux / sous la direction de Marie-Chantal Morel-Bracq ; [préface de Hélène Hernandez]. – 2e édition. – Louvain-la-Neuve : De Boeck Supérieur, 2017. – ix, 261 p. – 1 vol. broché de 16 × 24 cm. – 29,00 €. – isbn 978-2-35327-377-5.
Paul Mansion (1844-1919)
Authors: Mawhin Jean 
Published: February 2023

Les contributions de Paul Mansion aux mathématiques sont illustrées par son action pour l’emploi de la théorie des limites en géométrie élémentaire, par une description de son ouvrage Résumé d’analyse infinitésimale utilisé pour l’enseignement de cette branche à l’Université de Gand, par la discussion de son point de vue sur les infiniment petits et par l’étude de l’influence de son confrère De Tilly sur ses contributions à la géométrie non euclidienne. On discute enfin le rôle de Mansion comme animateur des mathématiques en Belgique.
* * *
The mathematical contributions of Paul Mansion to mathematics are illustrated by his action toward using the theory of limits in elementary geometry, by describing his textbook Résumé d’analyse infinitésimale used in his teaching of this discipline at the University of Gand, by discussing his viewpoint about the infinitesimals and by studying the influence of his fellow-member De Tilly on his contributions to non-Euclidian geometry. Finally, the role of Mansion in promoting mathematics in Belgium is emphasized.
L’idée de «Mathesis universalis» chez Leibniz
Authors: Radelet-de Grave Patricia 
Published: February 2023

Analyse critique de :
Leibniz (Gottfried Wilhelm), Mathesis universalis : écrits sur la mathématique universelle / textes introduits, traduits et annotés sous la direction de David Rabouin. – Paris : Vrin, 2018. – 256 p. – (Mathesis). – 1 vol. broché de 13,5 × 21,5 cm. – 23,00 €. – isbn 978-2-7116-2816-2.
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of lamotrigine in human serum and plasma
Authors: Salzmann Linda , Spescha Tino , Singh Neeraj , Schierscher Tobias , Bachmann Martina , Bauland Friederike , Geistanger Andrea , Risch Lorenz , Geletneky Christian , Seger Christoph , Taibon Judith 
Published: February 2023

Abstract

Objectives
We developed an isotope dilution (ID)-liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based candidate reference measurement procedure (RMP) for lamotrigine in human serum and plasma, using quantitative nuclear magnetic resonance-characterized reference standards to ensure traceability to the International System of Units.

Methods
A sample preparation protocol based on protein precipitation combined with LC-MS/MS analysis using a C18 column for chromatographic separation was established for the quantification of lamotrigine in human serum and plasma. Assay validation was performed according to current guidelines. Spiked serum and plasma samples were used to assess selectivity and specificity; a post-column infusion experiment and comparison of standard line slopes were performed to ascertain possible matrix effects. Precision and accuracy were determined in a 5 days validation experiment. Measurement uncertainty was determined per the Guide to the Expression of Uncertainty in Measurement.

Results
The method allowed the quantification of lamotrigine in serum and plasma in a range of 0.600–24.0 μg/mL without any observable matrix effects. The relative mean bias (n=6) ranged from 1.7 to 3.7%; intermediate precision, including variances in between-day, -calibration, and -injection, was ≤2.4%, independent of the level and matrix. Total measurement uncertainty for a single measurement was ≤2.6%; expanded uncertainty was ≤5.2% (coverage factor k=2).

Conclusions
This candidate RMP based on ID-LC-MS/MS provides a traceable and reliable platform for the standardization of routine assays and the evaluation of clinical samples.
Fractional Laplacian – Quadrature Rules for Singular Double Integrals in 3D
Authors: Feist Bernd , Bebendorf Mario 
Published: February 2023

Abstract
In this article, quadrature rules for the efficient computation of the stiffness matrix for the fractional Laplacian in three dimensions are presented.
These rules are based on the Duffy transformation, which is a common tool for singularity removal.
Here, this transformation is adapted to the needs of the fractional Laplacian in three dimensions.
The integrals resulting from this Duffy transformation are regular integrals over less-dimensional domains.
We present bounds on the number of Gauss points to guarantee error estimates which are of the same order of magnitude as the finite element error.
The methods presented in this article can easily be adapted to other singular double integrals in three dimensions with algebraic singularities.
Motivation and growth in kanji proficiency: a longitudinal study using latent growth curve modeling
Authors: Tanaka Mitsuko 
Published: February 2023

Abstract
Despite the well acknowledged importance of motivation in second language (L2) learning, longitudinal research regarding the effects of motivation on growth in L2 proficiency remains limited. Furthermore, limited investigation has been done on how motivation and L2 proficiency interactively develop and affect each other. Thus, this study examined the impact of motivation on growth in kanji proficiency and the dual developmental trajectories of motivation and kanji proficiency using the self-determination theory. Learners of Japanese with Chinese as their First language (L1) responded to a questionnaire and took kanji tests three times in one academic semester (n = 192). The results of the univariate latent growth curve (LGC) modeling identified intrinsic motivation and introjected regulation as positive and negative predictors, respectively, of kanji proficiency growth, suggesting the importance of enjoyment and the detrimental nature of introjected regulation in kanji learning by L1 Chinese learners. The results of multivariate LGC modeling demonstrated a lack of reciprocal developmental association between kanji proficiency and intrinsic motivation. Moreover, perceived competence rather than actual growth in kanji proficiency influenced the enhancement of intrinsic motivation, indicating the importance of subjective interpretations of L2 development in promoting motivation.
Treatments for brain metastases from EGFR/ALK-negative/unselected NSCLC: A network meta-analysis
Authors: Zhang Chengkai , Zhou Wenjianlong , Zhang Dainan , Ma Shunchang , Wang Xi , Jia Wang , Guan Xiudong , Qian Ke 
Published: February 2023

Abstract
More clinical evidence is needed regarding the relative priority of treatments for brain metastases (BMs) from EGFR/ALK-negative/unselected non-small cell lung cancer (NSCLC). PubMed, EMBASE, Web of Science, Cochrane Library, and ClinicalTrials.gov databases were searched. Overall survival (OS), central nervous system progression-free survival (CNS-PFS), and objective response rate (ORR) were selected for Bayesian network meta-analyses. We included 25 eligible randomized control trials (RCTs) involving 3,054 patients, investigating nine kinds of treatments for newly diagnosed BMs and seven kinds of treatments for previously treated BMs. For newly diagnosed BMs, adding chemotherapy, EGFR-TKIs, and other innovative systemic agents (temozolomide, nitroglycerin, endostar, enzastaurin, and veliparib) to radiotherapy did not significantly prolong OS than radiotherapy alone; whereas radiotherapy + nitroglycerin showed significantly better CNS-PFS and ORR. Surgery could significantly prolong OS (hazard ratios [HR]: 0.52, 95% credible intervals: 0.41–0.67) and CNS-PFS (HR: 0.32, 95% confidence interval: 0.18–0.59) compared with radiotherapy alone. For previously treated BMs, pembrolizumab + chemotherapy, nivolumab + ipilimumab, and cemiplimab significantly prolonged OS than chemotherapy alone. Pembrolizumab + chemotherapy also showed better CNS-PFS and ORR than chemotherapy. In summary, immune checkpoint inhibitor (ICI)-based therapies, especially ICI-combined therapies, showed promising efficacies for previously treated BMs from EGFR/ALK-negative/unselected NSCLC. The value of surgery should also be emphasized. The result should be further confirmed by RCTs.
High-performance waveguide coupled Germanium-on-silicon single-photon avalanche diode with independently controllable absorption and multiplication
Authors: Wang Heqing , Shi Yang , Zuo Yan , Yu Yu , Lei Lei , Zhang Xinliang , Qian Zhengfang 
Published: February 2023

Abstract
Germanium-on-silicon (Ge-on-Si) single photon avalanche diodes (SPADs) have received wide attention in recent years due to their potential to be integrated with Si photonics. In this work, we propose and demonstrate a high-performance waveguide coupled Ge-on-Si separate-absorption-charge-multiplication SPAD with three electric terminals. By providing two separate voltage drops on the light absorption and multiplication regions, the drift and multiplication of carriers can be optimized separately. This indeed improves the freedom of voltage regulation for both areas. Moreover, thanks to the separate controlling, doping profile of the charge layer is greatly released compared to that of the conventional device because of the flexible carrier injection. In this scenario, the dark counts of the detector can be largely reduced through decreasing the electric field on the sidewalls of the Ge absorption region without affecting the detection efficiency. The proposed SPAD exhibits a high on-chip single photon detection efficiency of 34.62% and low dark count rates of 279 kHz at 1310 nm with the temperature of 78 K. The noise equivalent power is as low as 3.27 × 10−16 WHz−1/2, which is, to the best of our knowledge, the lowest of that of the reported waveguide coupled Ge-on-Si SPADs. This three-terminal SPAD enables high-yield fabrication and provides robust performance in operation, showing a wide application prospect in applications such as on-chip quantum communication and lidar.
The crystal structure of N′1,N′2-bis((E)-3-(tert-butyl)-2-hydroxybenzylidene)oxalohydrazide, C24H30N4O4
Authors: Xiao Zhenxiu , Wang Tiantian , Deng Xin , Jiang Wujiu , Tan Yuxing 
Published: February 2023

Abstract
C24H30N4O4, monoclinic, C2/c (no. 15), a = 21.170(3) Å, b = 13.2938(17) Å, c = 9.7133(12) Å, β = 114.423(2)°, V = 2489.0(5) Å3, Z = 4, Rgt
(F) = 0.0473, wRref
(F
2) = 0.1424, T = 296(2) K.
The crystal structure of trimethyl 2,2′,2′′-(benzene-1,3,5-triyltris(oxy))triacetate, C15H18O9
Authors: Wang Tiantian , Su Yizi , Feng Yunyun , Tan Yuxing 
Published: February 2023

Abstract
C15H18O9, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 8.4962(7) Å, b = 8.6835(7) Å, c = 11.9767(10) Å, α = 90.9650(10)°, β = 94.9460(10)°, γ = 115.9310(10)°, V = 790.21(11) Å3, Z = 2, R

gt
(F) = 0.0318, wR

ref
(F
2) = 0.0855, T = 296(2) K.
Matrix metalloproteinase 9 gene-MMP9-DNA methylation status in Turkish schizophrenia patients
Authors: Karaaslan Ezgi , Kartalci Şükrü , Bağ Harika Gözde Gözükara , Acar Ceren 
Published: February 2023

Abstract

Objectives
Schizophrenia is a neuropsychiatric disease caused by disorders in brain development due to genetic and environmental factors. The interactions and mechanisms of the two main etiological factors are not fully understood despite neurobiological, clinical and genetic research and more research is needed. In this study, we aimed to investigate the DNA methylation differences in the matrix metalloproteinase 9 gene (MMP9) between schizophrenia and healthy control groups.

Methods
Our study investigates DNA methylation patterns in the MMP9 gene in peripheral blood cells of schizophrenia patients. For this purpose, pyrosequencing method was used to analyze DNA methylation status of C-phosphate-G (CpG) regions in the 7th exon of MMP9 in 40 schizophrenia patients and 32 healthy individuals who admitted to our university hospital’s psychiatry clinic.

Results
In our results, it has been shown that there is a difference between MMP9 gene DNA methylations between healthy individuals and schizophrenia patients. Significant differences were found in the MMP9 gene exon 7 region in CpG 7-3, CpG 7-4, CpG 7-5 positions and mean methylation patterns between these two groups.

Conclusions
This study provided evidence that DNA methylation differences may exist between schizophrenia patients and healthy individuals, and emphasized the epigenetic aspect of the disorder.
Impaired Autophagic-Lysosomal Fusion in Parkinson's Patient Midbrain Neurons Occurs through Loss of ykt6 and Is Rescued by Farnesyltransferase Inhibition
Authors: Pitcairn Caleb , Murata Naomi , Zalon Annie J. , Stojkovska Iva , Mazzulli Joseph R. 
Published: February 2023

Macroautophagy is a catabolic process that coordinates with lysosomes to degrade aggregation-prone proteins and damaged organelles. Loss of macroautophagy preferentially affects neuron viability and is associated with age-related neurodegeneration. We previously found that α-synuclein (α-syn) inhibits lysosomal function by blocking ykt6, a farnesyl-regulated soluble NSF attachment protein receptor (SNARE) protein that is essential for hydrolase trafficking in midbrain neurons. Using Parkinson's disease (PD) patient iPSC-derived midbrain cultures, we find that chronic, endogenous accumulation of α-syn directly inhibits autophagosome-lysosome fusion by impairing ykt6-SNAP-29 complexes. In wild-type (WT) cultures, ykt6 depletion caused a near-complete block of autophagic flux, highlighting its critical role for autophagy in human iPSC-derived neurons. In PD, macroautophagy impairment was associated with increased farnesyltransferase (FTase) activity, and FTase inhibitors restored macroautophagic flux through promoting active forms of ykt6 in human cultures, and male and female mice. Our findings indicate that ykt6 mediates cellular clearance by coordinating autophagic-lysosomal fusion and hydrolase trafficking, and that macroautophagy impairment in PD can be rescued by FTase inhibitors.SIGNIFICANCE STATEMENTThe pathogenic mechanisms that lead to the death of neurons in Parkinson's disease (PD) and Dementia with Lewy bodies (LBD) are currently unknown. Furthermore, disease modifying treatments for these diseases do not exist. Our study indicates that a cellular clearance pathway termed autophagy is impaired in patient-derived culture models of PD andin vivo. We identified a novel druggable target, a soluble NSF attachment protein receptor (SNARE) protein called ykt6, that rescues autophagyin vitroandin vivoupon blocking its farnesylation. Our work suggests that farnesyltransferase (FTase) inhibitors may be useful therapies for PD and DLB through enhancing autophagic-lysosomal clearance of aggregated proteins.
Large scale multilingual sticker recommendation in messaging apps
Authors: Laddha Abhishek , Hanoosh Mohamed , Mukherjee Debdoot , Patwa Parth , Narang Ankur 
Published: February 2023

AbstractStickers are popularly used while messaging to visually express nuanced thoughts. We describe a real‐time sticker recommendation (SR) system. We decompose SR into two steps: predict the message that is likely to be sent, and substitute that message with an appropriate sticker. To address the challenges caused by transliteration of message from users' native language to the Roman script, we learn message embeddings by employing character‐level CNN in an unsupervised manner. We use them to cluster semantically similar messages. Next, we predict the message cluster instead of the message. Except for validation, our system does not require human labeled data, leading to a fully automatic tuning pipeline. We propose a hybrid message prediction model, which can easily run on low‐end phones. We discuss message cluster to sticker mapping, addressing the multilingual needs of our users, automated tuning of the system and also propose a novel application of community detection algorithm. As of November 2020, our system contains 100k+ stickers, has been deployed for 15+ months, and is being used by millions of users.
On the care and feeding of virtual assistants: Automating conversation review with AI
Authors: Beaver Ian , Mueen Abdullah 
Published: February 2023

AbstractWith the rise of intelligent virtual assistants (IVAs), there is a necessary rise in human effort to identify conversations containing misunderstood user inputs. These conversations uncover error in natural language understanding and help prioritize improvements to the IVA. As human analysis is time consuming and expensive, prioritizing the conversations where misunderstanding has likely occurred reduces costs and speeds IVA improvement. In addition, less conversations reviewed by humans mean less user data are exposed, increasing privacy. We describe Trace AI, a scalable system for automated conversation review based on the detection of conversational features that can identify potential mis‐communications. Trace AI provides IVA designers with suggested actions to correct understanding errors, prioritizes areas of language model repair, and can automate the review of conversations. We discuss the system design and report its performance at identifying errors in IVA understanding compared to that of human reviewers. Trace AI has been commercially deployed for over 4 years and is responsible for significant savings in human annotation costs as well as accelerating the refinement cycle of deployed enterprise IVAs.
Will AI write scientific papers in the future?
Authors: Gil Yolanda 
Published: February 2023

AbstractIn this presidential address, I would like to start with a personal reflection on the field and then share with you the research directions I am pursuing and my excitement about the future of AI. In my personal research to advance AI while advancing scientific discoveries, one question that I have been pondering for some years now is whether AI will write scientific papers in the future. I want to reflect on this question, and look back at the many accomplishments in our field that can make us very hopeful that the answer will be yes, and that it may happen sooner than we might expect.
Peningkatan literasi ibu sebagai upaya pencegahan stunting di Desa Wonorejo Kabupaten Malang
Authors: Samah Dea Aflah , Bachtiar Belisa Fitria Az zahra , AzZahra Annisa Aulia , Ramadhani Yuanda Putri Rizki , Afandi Alvisar , Wahyuni Oktavia Sri , Katmawanti Septa 
Published: February 2023

Desa Wonorejo sendiri memiliki jumlah kasus sebanyak 120 balita stunting dengan penyebab multikausa salah satunya kurangnya pengetahuan ibu dalam mengolah MP-ASI. Rendahnya pengetahuan para ibu akan pengolahan menu ini sangat berdampak signifikan terhadap tumbuh kembang anak. Dengan permasalahan tersebut, butuhnya solusi yang tepat. Peningkatan Literasi Ibu Melalui Keterampilan Mengolah Menu MP-ASI merupakan terobosan dalam upaya preventif pencegahan stunting di Desa Wonorejo. Terobosan ini didukung dengan media promosi kesehatan berupa kalender menu MPASI dimana kalender tersebut menyajikan resep menu MPASI, manajemen MPASI, dan juga kandungan gizi dari setiap bahan makanan. Kegiatan ini dilakukan dengan bertatap langsung dengan ibu-ibu di Desa Wonorejo dan tetap menerapkan protokol kesehatan yang ketat. Kegiatan pertama dilakukan dengan diberikannya modul berbentuk kalender MP-ASI lalu diberikan sebuah kuesioner untuk mengetahui karakteristik, pengetahuan, dan sikap para ibu di Desa Wonorejo. Hasil penilaian pengetahuan Ibu di desa Wonorejo setelah diberikannya modul kalender MPASI sudah menunjukkan kategori baik. Untuk hasil penilaian sikap ibu terhadap MPASI sudah dalam kategori cukup. Dapat disimpulkan bahwa modul kalender MP-ASI dapat menjadi salah satu sarana untuk meningkatkan literasi ibu terutama dalam hal MP-ASI yang mana pemberian MP-ASI yang baik dapat mencegah terjadinya stunting.