bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bacteria-phage coevolution with a seed bank
Authors: Schwartz Daniel A , Shoemaker William R , Măgălie Andreea , Weitz Joshua S , Lennon Jay T 
Published: June 2023

Abstract
Dormancy is an adaptation to living in fluctuating environments. It allows individuals to enter a reversible state of reduced metabolic activity when challenged by unfavorable conditions. Dormancy can also influence species interactions by providing organisms with a refuge from predators and parasites. Here we test the hypothesis that, by generating a seed bank of protected individuals, dormancy can modify the patterns and processes of antagonistic coevolution. We conducted a factorially designed experiment where we passaged a bacterial host (Bacillus subtilis) and its phage (SPO1) in the presence versus absence of a seed bank consisting of dormant endospores. Owing in part to the inability of phages to attach to spores, seed banks stabilized population dynamics and resulted in minimum host densities that were 30-fold higher compared to bacteria that were unable to engage in dormancy. By supplying a refuge to phage-sensitive strains, we show that seed banks retained phenotypic diversity that was otherwise lost to selection. Dormancy also stored genetic diversity. After characterizing allelic variation with pooled population sequencing, we found that seed banks retained twice as many host genes with mutations, whether phages were present or not. Based on mutational trajectories over the course of the experiment, we demonstrate that seed banks can dampen bacteria-phage coevolution. Not only does dormancy create structure and memory that buffers populations against environmental fluctuations, it also modifies species interactions in ways that can feed back onto the eco-evolutionary dynamics of microbial communities.
Preclinical optimization of a diode laser-based clamp-free partial nephrectomy in a large animal model
Authors: Andrade Weslley S. , Tang Fenny H. F. , Mariotti Antonio C. H. , Mancini Marilia W. , Duarte Ivison X. , Singer Eric A. , Weiss Robert E. , Pasqualini Renata , Arap Wadih , Arap Marco A. 
Published: June 2023

AbstractKidney cancer is a common urologic malignancy with either laparoscopic (LPN) or robotic partial nephrectomy as therapeutic options of choice for localized tumors. However, renal resection and suturing are challenging steps of the procedure that can lead to complications such as prolonged warm ischemia, bleeding, and urinary fistulas. LPN with a diode laser is an efficient technique due to its cutting and/or coagulation attributes. Surprisingly, key laser features such as wavelength and power remain undefined. Using a large porcine model, we evaluated the laser range of wavelength and power in a clamp-free LPN and compared it to the established gold-standard LPN technique (i.e., cold-cutting and suturing). By analyzing surgery duration, bleeding, presence of urine leak, tissue damage related to the resected renal fragment and the remaining organ, hemoglobin levels, and renal function, we show that an optimized experimental diode laser clamp-free LPN (wavelength, 980 nm; power, 15 W) had shorter surgery time with less bleeding, and better postoperative renal function recovery when compared to the well-established technique. Together, our data indicate that partial nephrectomy with a diode laser clamp-free LPN technique is an improved alternative to the gold-standard technique. Therefore, translational clinical trials towards human patient applications are readily feasible.
GTMNet: a vision transformer with guided transmission map for single remote sensing image dehazing
Authors: Li Haiqin , Zhang Yaping , Liu Jiatao , Ma Yuanjie 
Published: June 2023

AbstractExisting dehazing algorithms are not effective for remote sensing images (RSIs) with dense haze, and dehazed results are prone to over-enhancement, color distortion, and artifacts. To tackle these problems, we propose a model GTMNet based on convolutional neural networks (CNNs) and vision transformers (ViTs), combined with dark channel prior (DCP) to achieve good performance. Specifically, a spatial feature transform (SFT) layer is first used to smoothly introduce the guided transmission map (GTM) into the model, improving the ability of the network to estimate haze thickness. A strengthen-operate-subtract (SOS) boosted module is then added to refine the local features of the restored image. The framework of GTMNet is determined by adjusting the input of the SOS boosted module and the position of the SFT layer. On SateHaze1k dataset, we compare GTMNet with several classical dehazing algorithms. The results show that on sub-datasets of Moderate Fog and Thick Fog, the PSNR and SSIM of GTMNet-B are comparable to that of the state-of-the-art model Dehazeformer-L, with only 0.1 times of parameter quantity. In addition, our method is intuitively effective in improving the clarity and the details of dehazed images, which proves the usefulness and significance of using the prior GTM and the SOS boosted module in a single RSI dehazing.
High dose of dexamethasone attenuates docetaxel-induced fluid retention in breast cancer treatment
Authors: Saito Yoshitaka , Kanno Ryota , Takekuma Yoh , Takeshita Takashi , Oshino Tomohiro , Sugawara Mitsuru 
Published: June 2023

AbstractDocetaxel-induced fluid retention (DIFR) cumulatively occurs and is one of the most troublesome adverse effects. This study aimed to determine whether high dose dexamethasone (DEX) could prevent DIFR during breast cancer treatment. Breast cancer patients receiving docetaxel (75 mg/m2)-containing regimens were divided into 4 and 8 mg/day DEX groups, with each DEX dose administered on days 2–4 and retrospectively assessed. Incidence of greater than or equal to grade 2 DIFR was significantly lower in the 8 mg group (13.0%) compared to the 4 mg group (39.6%, P = 0.001). All-grade DIFR was also less in the 8 mg group (P = 0.01). Furthermore, the maximum variation of body weight was significantly lower in the 8 mg group (P = 0.0003). These results were also confirmed in the propensity score-matched population. Additionally, time-related DIFR incidence was also significantly delayed in the 8 mg group (P = 0.0005). Our study revealed that high dose DEX prevents DIFR. Therefore, further studies on its management are required for less onerous chemotherapy provision with better DIFR control.
Nanophotonic resonator assisted photonic spin Hall enhancement for sensing application
Authors: Goyal Amit Kumar , Divyanshu Divyanshu , Massoud Yehia 
Published: June 2023

AbstractThis manuscript presents a dielectric resonator structure with altered dispersion characteristics to enhance the photonic spin Hall effect (PSHE). The structural parameters are optimized to enhance the PSHE at 632.8 nm operating wavelength. The thickness-dependent angular dispersion analysis is carried out to optimize the structure and obtain the exceptional points. The PSHE-induced spin splitting shows a high sensitivity to the optical thickness of the defect layer. This gives a maximum PSHE-based transverse displacement (PSHE-TD) of around 56.66 times the operating wavelength at an incidence angle of 61.68°. Moreover, the structure’s capability as a PSHE-based refractive index sensor is also evaluated. The analytical results demonstrate an average sensitivity of around 33,720 μm/RIU. The structure exhibits around five times higher PSHE-TD and approximately 150% improvement in sensitivity than the recently reported values in lossy mode resonance structures. Due to the purely dielectric material-assisted PhC resonator configurations and significantly higher PSHE-TD, the development of low-cost PSHE-based devices for commercial applications is envisaged.
Tox4 regulates transcriptional elongation and reinitiation during murine T cell development
Authors: Wang Talang , Zhao Ruoyu , Zhi Junhong , Liu Ziling , Wu Aiwei , Yang Zimei , Wang Weixu , Ni Ting , Jing Lili , Yu Ming 
Published: June 2023

AbstractHMG protein Tox4 is a regulator of PP1 phosphatases with unknown function in development. Here we show that Tox4 conditional knockout in mice reduces thymic cellularity, partially blocks T cell development, and decreases ratio of CD8 to CD4 through decreasing proliferation and increasing apoptosis of CD8 cells. In addition, single-cell RNA-seq discovered that Tox4 loss also impairs proliferation of the fast-proliferating double positive (DP) blast population within DP cells in part due to downregulation of genes critical for proliferation, notably Cdk1. Moreover, genes with high and low expression level are more dependent on Tox4 than genes with medium expression level. Mechanistically, Tox4 may facilitate transcriptional reinitiation and restrict elongation in a dephosphorylation-dependent manner, a mechanism that is conserved between mouse and human. These results provide insights into the role of TOX4 in development and establish it as an evolutionarily conserved regulator of transcriptional elongation and reinitiation.
Beyond the Stuttering Toolbox: The Concept of Meta-Therapy
Authors: Gore Katie , Margulis Courtney L. 
Published: June 2023

Purpose:The purpose of this clinical focus article is to describe how meta-therapy applies to stuttering treatment.Method:We briefly summarize the concept ofmeta-therapy, which was first introduced by Helou (2017) in the context of behavioral voice therapy. We then apply basic meta-therapy principles to stuttering, with the goal of helping novice clinicians leverage their clinical dialogue to improve effectiveness and efficiency in the treatment setting. Examples of effective clinical dialogues are presented within the basic goal-based structure of meta-therapy.Conclusion:The application of meta-therapy approaches in stuttering treatment should improve outcomes and increase efficiency.
Abordaje Volar de las Fracturas de Radio Distal y la Vaina del Flexor Carpi Radialis. Una Encuesta Regional y Nacional
Authors: Scott-Tennent De Rivas Ana , Forcada Calvet Pau , Mustafa Gondolbeu Amer , Prats Gispert Laura , Bonjorn Martí Marta 
Published: June 2023

Resumen
Introducción Se han descrito diferentes abordajes volares para para la osteosíntesis de las fracturas de radio distal; algunos de ellos acceden a través de la vaina del flexor carpi radialis (FCR) (Abordaje FCR), mientras que otros evitan abrirla (Abordaje Henry clásico). En la literatura no encontramos estudios que comparen si existen diferencias entre ellos. Nuestra hipótesis es que, a pesar de ello, existen diferentes opiniones al respecto entre los cirujanos que operan estas fracturas.
Materiales y métodos Se realizó una encuesta online a los miembros de la Societat Catalana de Cirurgia Ortopèdica i Traumatologia (SCCOT) y a los de la Sociedad Española de Cirugía de Mano (SECMA) a través de un cuestionario anónimo utilizando la plataforma de SurveyMonkey (Momentive Inc., San Mateo, California, EE. UU.
www.momentive.ai) con el objetivo de valorar sus preferencias con respecto al manejo de la vaina del tendón del FCR. El análisis de las respuestas se realizó a través de tablas con filtros y tabulaciones cruzadas utilizando el software de análisis del mismo programa.
Resultados Desde Octubre 2020-2021 se obtuvieron 99 respuestas, 55 cirujanos de extremidad superior o mano y 41 cirujanos ortopédicos generales. 72,72% abren la vaina del FCR, 63% creen que ello facilita su cirugía. 21,21% prefiere respetar la vaina tendinosa y el 53% opinan que preservarla disminuye el riesgo de complicaciones, siendo el exceso de fibrosis y la lesión yatrogénica de las estructuras neurovasculares las más temidas.
Conclusiones Creemos que existe discrepancia de opiniones en cuanto al manejo de la vaina del tendón del FCR en el abordaje volar de las fracturas de radio distal y la justificación de elegir un abordaje u otro. Dada la alta incidencia de estas fracturas y la ausencia de análisis clínicos previos, los resultados obtenidos en esta encuesta podrían servir como base para la realización de estudios clínicos en el futuro.
Artrodesis Total de la Muñeca con Placa Dorsal Bloqueada de Bajo Perfil y Ángulo Variable: Tasa de Consolidación y Complicaciones de 85 casos Consecutivos
Authors: Vasquez Eduardo Farias , Siestrup Pedro Henrique Martinez Grosse , Guedes Giovanni Vilardo Cerqueira , Barbosa Rafael Sousa Lima , Monteiro Anderson Vieira , Couto Arnaldo 
Published: June 2023

Resumen
Introducción La artrodesis de muñeca ha evolucionado con el tiempo con el uso creciente de un implante más rígido y un aumento resultante en las tasas de consolidación. Sin embargo, complicaciones como la irritación de los tendones extensores han llevado al desarrollo e introducción de implantes mejorados de bajo perfil en los últimos años. Este estudio tuvo como objetivo examinar los factores que influyen en la curación de la artrodesis total de la muñeca y la frecuencia de complicaciones utilizando una placa de bajo perfil del mismo fabricante.
Materiales y métodos Se trata de un estudio retrospectivo que analiza las historias clínicas y radiografías de pacientes sometidos a artrodesis de muñeca utilizando una placa de fusión de muñeca Aptus® 2.5 Trilock larga o corta (Medartis AG, Basilea, Suiza) entre 2015 y 2021 en el mismo hospital. Se analizaron variables epidemiológicas y clínicas. La prueba de Chi-cuadrado o Prueba exacta de Fischer se utilizó para comparar las proporciones y los resultados, con un valor p ≤ 0,05 que se considera estadísticamente significativo.
Resultados De las 85 artrodesis de muñeca realizadas, se observó una consolidación del 100% en un promedio de 4,6 meses después de la cirugía. La mayoría de los pacientes eran no fumadores (80%), hombres (69,4%), con una edad media de 50,7 años. La tasa de complicaciones fue del 10,5%, todas las cuales se resolvieron después de una intervención adicional, requiriendo solo una extracción del implante. El tiempo medio de consolidación en los fumadores fue de 5,8 meses y en los no fumadores de 4,2 meses (p = 0,03). El tiempo medio de consolidación después de los procedimientos de placa larga fue sutilmente más corto que con el uso de placa corta, pero no tuvo significación estadística.
Conclusión Las artrodesis de la muñeca en el presente estudio tuvieron una tasa de consolidación del 100% con una baja tasa de complicaciones y sin diferencias en los resultados en cuanto a la colocación del injerto, la fusión de la articulación carpometacarpiana o los perfiles demográficos de los pacientes. Fumar se asoció con un mayor tiempo de consolidación, pero no condujo a la pseudoartrosis.
Grado de comprobación IV
Attojoule/bit folded thin film lithium niobate coherent modulators using air-bridge structures
Authors: Xu Mengyue , Zhu Yuntao , Tang Jin , Wang Jingyi , Liu Lin , Ma Huixiao , Yu Siyuan , Zheng Bofang , Cai Xinlun 
Published: June 2023

Coherent technology has been employed in long-haul transmission systems in the past decade, with growing demand for capacity at ever-lower costs per bit. High-performance coherent modulators with high data rates, wide bandwidth, small footprint, and low power operation are highly desired. Toward this end, we propose a folded thin-film lithium niobate (TFLN) dual-polarization in-phase quadrature modulator featuring a low half-wave voltage of 1 V and a compact footprint of 4 × 8 mm2. To suppress RF wavefront distortion and optimize high-frequency electro-optic performance, we utilize air-bridge structures in the U-turns of the traveling-wave electrodes. As a demonstration of the long-haul transmission capacities with our device, we present driverless 703 Gb/s/λ line-rate transmissions, with a subcarrier modulation scheme, over a 1120 km single-mode fiber link. Here, for the first time, to our knowledge, our device allows for attojoule-per-bit level electrical energy consumption over transmission distances above 1000 km. The device opens opportunities for much lower-cost and capacity-intensive coherent systems that consume ultra-low power, support high data rate, and work in small spaces.
Supplementary comparison on digital multimeter
Authors: Ahmad Saood , John Thomas , Negi P S , Marais Louis , Prinsloo Flippie , Matlejoane Alexander , Jargal Arjuntungalag , Tanarom Jutarat , Rujirat Narat , Yang Steven , Hassan Nor Azrin , Alanka R D M , KieuLinh Phung Thi , Jr Sabino Paulo B Leones , Panga Joe , Gabi Victor , Maruf Ahnan , Konkanov Marat , Nurlan Seksembaev , Tadros Nadia N , Sayed Dr Rasha , Harba Naser , Flaifel Mustafa , Choon Tay Siew 
Published: June 2023

Main text
A measurement comparison of DC voltage, DC current, DC resistance, AC voltage and AC current has been carried out among seventeen national metrology laboratories with the travelling standards 6½ digit multimeter (Fluke model 8846A) as Loop A, Loop B and Loop C for the nominal values of the measured parameters DC voltage (100 mV, 1 V, 10 V, -10 V, 100 V and 1000 V), DC current (10 mA and 1 A), DC resistance (100 Ω, 1 kΩ and 10 kΩ (using 4-wire), AC voltage (100 mV, 1 V, 10 V, 100 V and 700 V at 40 Hz and 1 kHz) and AC current (10 mA and 1 A at 40 Hz and 1 kHz) for establishing the degrees of equivalence among the participating NMIs. This is the final report on the comparison. The report presents the combined results (Loop A, Loop B and Loop C), represented by corrections in measured parameters and the corresponding expanded uncertainties. The combined results from the three loops have been used to calculate the Supplementary Comparison Reference Values, degrees of equivalence di and corresponding uncertainties u(di) of each laboratory that participated in the comparison.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
A novel quantitative inverse scattering scheme using interior resonant modes
Authors: He Youzi , Liu Hongyu , Wang Xianchao 
Published: June 2023

Abstract
This paper is devoted to a novel quantitative imaging scheme of identifying impenetrable obstacles in time-harmonic acoustic scattering from the associated far-field data. The proposed method consists of two phases. In the first phase, we determine the interior eigenvalues of the underlying unknown obstacle from the far-field data via the indicating behavior of the linear sampling method. Then we further determine the associated interior eigenfunctions by solving a constrained optimization problem, again only involving the far-field data. In the second phase, we propose a novel iteration scheme of Newton’s type to identify the boundary surface of the obstacle. By using the interior eigenfunctions determined in the first phase, we can avoid computing any direct scattering problem at each Newton’s iteration. The proposed method is particularly valuable for recovering a sound-hard obstacle, where the Newton’s formula involves the geometric quantities of the unknown boundary surface in a natural way. We provide rigorous theoretical justifications of the proposed method. Numerical experiments in both 2D and 3D are conducted, which confirm the promising features of the proposed imaging scheme. In particular, it can produce quantitative reconstructions of high accuracy in a very efficient manner.
A Text-Detecting Method Based on Improved CTPN
Authors: Zhang Shaowei , Duan Anming , Sun Yongjiao 
Published: June 2023

Abstract
In the intelligent electric power inspection system, when the nameplate image is collected on site and transmitted back to the server, the server system needs to identify the text information in the nameplate, and the detection of the text area is a key step. By discussing the CTPN algorithm, this paper proposes an improved CTPN text detection algorithm, which makes up for its shortcomings in identifying oblique text and further improves the detection precision.
A Novel Encoder-Decoder Structure-based Transformer for Fine-Resolution Remote Sensing Images
Authors: Wang Guixian , Huang Dandan , Geng ZhenYe , Liu Zhi , Duan Jin 
Published: June 2023

Abstract
Full convolution neural network (FCN) based on an encoder-decoder structure has become a standard network in the semantic segmentation domain. Encoder-decoder architecture is an effective means to get finer-grained performance. Encoders constantly extract multilevel features, and then use decoders to gradually introduce low-level features into high-level features. Context information is critical for accurate segmentation, which is the main direction of semantic segmentation at present. So many efforts have been made to make better use of this kind of information, including codec structure, void convolution (expanded convolution), and attention mechanism. However, most of these schemes are based on Resnet or other variants of convolution network FCN, which makes it unable to get rid of the defective local receptive field of convolution itself. In this work, we introduce the pyramid visual converter (PVT) to replace the traditional full convolution network architecture, and design a novel encoder-decoder architecture to more effectively utilize the context information.
Geometric uncertainty relations on Wigner–Yanase skew information
Authors: Chen Bin , Lian Pan 
Published: June 2023

Abstract
We formulate uncertainty relations based on Wigner–Yanase skew information. By using the Kirillov–Kostant–Souriau Kähler structure on the quantum phase space, we present a new geometric uncertainty relation associated to the skew information, which is shown to be tighter than the existing ones. Furthermore, we provide a skew information-based product uncertainty relation, in which the lower bound can also be used to capture the non-commutativity of the observables. We also attempt to generalize the geometric uncertainty inequalities to the case of arbitrary three observables, where the Kähler structure plays a vital role in the proof.
When a Series’ Main Protagonist Gets Stolen and Sold – A Study of NFTs and Their Approaches to Copyright Licensing
Authors: Bischoff Susan 
Published: June 2023

Abstract
Over the past two years non-fungible tokens (NFTs) have become a highly popular, though extremely volatile trade asset. As mere data sets on the blockchain, NFTs are challenging the law to define the legal positions they entail. This article examines NFTs from the angle of copyright licensing, looking at it from a European perspective with the main focus on German law. Based on the technical specifics of NFTs, the paper evaluates the relevant legal position required for a permitted use of tokenized copyrighted content and how such a position may be obtained in the context of NFT trading. A review of the copyright schemes of 21 of the most sought-after NFT collections sets out the current state of licensing and identifies the prevailing legal uncertainties. The fact that these are not merely theoretical is then shown by the turbulent case of a ‘stolen’ ape avatar, tokenized by an NFT, that was set to star in a live-action animated series.