bluuebunny/crossref_metadata_2025_split huggingface dataset:
Large-diameter trees and deadwood correspond with belowground ectomycorrhizal fungal richness
Authors: Birch Joseph D. , Lutz James A. , Struckman Soren , Miesel Jessica R. , Karst Justine 
Published: January 2023

Abstract
Background
Large-diameter trees have an outsized influence on aboveground forest dynamics, composition, and structure. Although their influence on aboveground processes is well studied, their role in shaping belowground fungal communities is largely unknown. We sought to test if (i) fungal community spatial structure matched aboveground forest structure; (ii) fungal functional guilds exhibited differential associations to aboveground trees, snags, and deadwood; and (iii) that large-diameter trees and snags have a larger influence on fungal community richness than smaller-diameter trees. We used MiSeq sequencing of fungal communities collected from soils in a spatially intensive survey in a portion of Cedar Breaks National Monument, Utah, USA. We used random forest models to explore the spatial structure of fungal communities as they relate to explicitly mapped trees and deadwood distributed across 1.15 ha of a 15.32-ha mapped subalpine forest.

Results
We found 6,177 fungal amplicon sequence variants across 117 sequenced samples. Tree diameter, deadwood presence, and tree species identity explained more than twice as much variation (38.7% vs. 10.4%) for ectomycorrhizal composition and diversity than for the total or saprotrophic fungal communities. Species identity and distance to the nearest large-diameter tree (≥ 40.2 cm) were better predictors of fungal richness than were the identity and distance to the nearest tree. Soil nutrients, topography, and tree species differentially influenced the composition and diversity of each fungal guild. Locally rare tree species had an outsized influence on fungal community richness.

Conclusions
These results highlight that fungal guilds are differentially associated with the location, size, and species of aboveground trees. Large-diameter trees are implicated as drivers of belowground fungal diversity, particularly for ectomycorrhizal fungi.
Night eating syndrome is associated with mental health issues among palestinian undergraduate students-cross sectional study
Authors: Hamdan May , Badrasawi Manal , Zidan Souzan , Thawabteh Ruba , Mohtaseb Raya , Arqoub Khozama Abu 
Published: January 2023

AbstractBackgroundUniversity students are exposed to several factors associated with Night Eating Syndrome NES, which is distinguished by nocturnal consumption and/or evening hyperphagia. The main purpose of the current study is to examine the state of NES, and to explore its relationship with selected factors (e.g. sociodemographic factors, lifestyle habits, body mass index “BMI”, and mental health) among a sample of undergraduates.MethodsA cross-section design was done among undergraduates recruited from three universities in the southern part of Palestine. Students completed a self-administrated questionnaire including demographic information, lifestyle habits, medical profile, and the Arabic version of Night Eating Questionnaire (NEQ). Mental health status was also assessed using the Arabic version of the 12-item General Health Questionnaire (GHQ-12). Cronbach alpha was used to check the reliability of the Arabic version of NEQ. Data were analyzed using univariate and multivariate approach.ResultsA total of 475 participants were included in the study, 197 (47%) males, 253(54%) females. Mean age was 19.8 ± 1.4 years, ranged from 18 to 25 years old. It is found that 141 university students (29.7%) screened positive for NES. According to univariate analysis, NES was significantly related to gender (p = 0.023), major (p = 0.005), personal monthly income (p = 0.007), source of funding (p = 0.005), and mental health (p < 0.005). Besides, the results of binary logistic regression revealed that having mental health problems (Exp (B) = 4.18; 95% CI = 2.50–6.98;p = 0.000), males (Exp (B) = 1.99; 95% CI = 1.17–3.39;p = 0.014), and those who study expenses was not covered either by scholarship or parents (Exp (B) = 2.75; 95% CI = 1.29–5.8;p = 0.08) were significantly associated with NES.ConclusionIt is found that NES is common among Palestinian university students. In this study, NES was significantly more prevalent among males, and those who were studying scientific majors, having a personal income between 500 and 1000 new Israeli shekel per month, and having mental problems, and those whose studies were funded by neither by a scholarship nor by their parents.
MiR-124-3p impedes the metastasis of non-small cell lung cancer via extracellular exosome transport and intracellular PI3K/AKT signaling
Authors: Zhu Qing , Zhang Yixuan , Li Mo , Zhang Ying , Zhang Huan , Chen Jiayi , Liu Zhaoyang , Yuan Peng , Yang Zhaogang , Wang Xiaobing 
Published: January 2023

Abstract
Background
Metastasis is a significant factor that affects the survival of patients with non-small cell lung cancer (NSCLC). Nevertheless, the molecular regulatory mechanism underlying the metastasis is currently not fully understood. This study aims to identify the important role of miR-124-3p in metastasis of NSCLC, thereby providing a potential therapeutic intervention.

Methods
Exosome secretion was determined by Nanoparticle Tracking Analysis (NTA) and the uptake was measured by fluorescence inverted microscope. The binding mechanism between miR-124-3p and its upstream or downstream target genes was validated experimentally by Luciferase reporter. Cells migration was evaluated by transwell assays. Transcriptome sequencing on A549 was carried out to verify the potential signaling pathway underlying miR-124-3p regulation. Western blotting analysis was used to assess the level of AKT, p-AKT, PI3K, and p-PI3K protein expression in NSCLC cell lines. The role of miR-124-3p to suppress the tumor metastasis was verified in NSCLC xenograft model.

Results
Exosomes were more abundant in serum from patients with advanced lung cancer (n = 24 patients) than in these from patients with early-stage lung cancer (n = 30 patients), which suggested the potential correlation between amount of exosome secretion and the metastasis of NSCLC. Interestingly, the exosome release, uptake and the migration of NSCLC cells were notably inhibited by miR-124-3p. LINC00511 suppressed the expression of miR-124-3p to facilitate exosome transport due to its role as the competitive endogenous RNA for miR-124-3p. The miR-124-3p could directly target the 3′-UTR of Rab27a in NSCLC cells to inhibit exosome secretion and thereby prevent cell migration and invasion. Aside from the inhibition of exosome transport, miR-124-3p inhibited the activation of PI3K/AKT signaling in the intracellular environment. Finally, by measuring subcutaneous tumor weight and volume and lung metastasis, we also demonstrated that miR-124-3p inhibited tumor growth in vivo.

Conclusion
In NSCLC, miR-124-3p significantly suppressed metastasis through extracellular exosome transport and intracellular PI3K/AKT signaling. These findings provide new insights toward a better understanding of the NSCLC metastasis and suggest a potential treatment biomarker for NSCLC.
Implementing PointNet for point cloud segmentation in the heritage context
Authors: Haznedar Bulent , Bayraktar Rabia , Ozturk Ali Emre , Arayici Yusuf 
Published: January 2023

Abstract
Automated Heritage Building Information Modelling (HBIM) from the point cloud data has been researched in the last decade as HBIM can be the integrated data model to bring together diverse sources of complex cultural content relating to heritage buildings. However, HBIM modelling from the scan data of heritage buildings is mainly manual and image processing techniques are insufficient for the segmentation of point cloud data to speed up and enhance the current workflow for HBIM modelling. Artificial Intelligence (AI) based deep learning methods such as PointNet are introduced in the literature for point cloud segmentation. Yet, their use is mainly for manufactured and clear geometric shapes and components. To what extent PointNet based segmentation is applicable for heritage buildings and how PointNet can be used for point cloud segmentation with the best possible accuracy (ACC) are tested and analysed in this paper. In this study, classification and segmentation processes are performed on the 3D point cloud data of heritage buildings in Gaziantep, Turkey. Accordingly, it proposes a novel approach of activity workflow for point cloud segmentation with deep learning using PointNet for the heritage buildings. Twenty-eight case study heritage buildings are used, and AI training is performed using five feature labelling for segmentation namely, walls, roofs, floors, doors, and windows for each of these 28 heritage buildings. The dataset is divided into clusters with 80% training dataset and 20% prediction test dataset. PointNet algorithm was unable to provide sufficient accuracy in segmenting the point clouds due to deformation and deterioration on the existing conditions of the heritage case study buildings. However, if PointNet algorithm is trained with the restitution-based heritage data, which is called synthetic data in the research, PointNet algorithm provides high accuracy. Thus, the proposed approach can build the baseline for the accurate classification and segmentation of the heritage buildings.
Predicting soil erosion potential under CMIP6 climate change scenarios in the Chini Lake Basin, Malaysia
Authors: Rendana Muhammad , Idris Wan Mohd Razi , Rahim Sahibin Abdul , Rahman Zulfahmi Ali , Lihan Tukimat 
Published: January 2023

AbstractClimate change and soil erosion are very associated with environmental defiance which affects the life sustainability of humans. However, the potency effects of both events in tropical regions are arduous to be estimated due to atmospheric conditions and unsustainable land use management. Therefore, several models can be used to predict the impacts of distinct climate scenarios on human and environmental relationships. In this study, we aimed to predict current and future soil erosion potential in the Chini Lake Basin, Malaysia under different Climate Model Intercomparison Project-6 (CMIP6) scenarios (e.g., SSP2.6, SSP4.5, and SSP8.5). Our results found the predicted mean soil erosion values for the baseline scenario (2019–2021) was around 50.42 t/ha year. The mining areas recorded the highest soil erosion values located in the southeastern part. The high future soil erosion values (36.15 t/ha year) were obtained for SSP4.5 during 2060–2080. Whilst, the lowest values (33.30 t/ha year) were obtained for SSP2.6 during 2040–2060. According to CMIP6, the future soil erosion potential in the study area would reduce by approximately 33.9% compared to the baseline year (2019–2021). The rainfall erosivity factor majorly affected soil erosion potential in the study area. The output of the study will contribute to achieving the United Nations' 2030 Agenda for Sustainable Development.
Trade credit financing for supply chain coordination under financial challenges: a multi-leader–follower game approach
Authors: Emtehani Faranak , Nahavandi Nasim , Rafiei Farimah Mokhatab 
Published: January 2023

AbstractThis study is designed to solve supply chain inefficiencies caused by some members' financial problems, such as capital shortages and financing restrictions in a stochastic environment. To this end, we have established a supply chain finance framework by designing two novel coordinating contracts based on trade credit financing for different problem settings. These contracts are modeled in the form of multi-leader Stackelberg games that address horizontal and vertical competition in a supply chain consisting of multiple suppliers and a financially constrained manufacturer. However, previous studies in the trade credit literature have addressed only simple vertical competition, that is, seller-buyer competition. To solve the proposed models, two algorithms were developed by combining population-based metaheuristics, the Nash-domination concept, and the Nikaido-Isoda function. The results demonstrate that the proposed supply chain finance framework can eliminate supply chain inefficiencies and make a large profit for suppliers, as well as the financially constrained manufacturer. Furthermore, the results of the contracts’ analysis showed that if the manufacturer is required to settle its payments to suppliers before the end of the period, the trade credit contract cannot coordinate the supply chain because of a lack of incentive for suppliers. However, if the manufacturer is allowed to extend its payments to the end of the period, the proposed trade credit financing contract can coordinate the supply chain. Finally, the sensitivity analysis results indicate that the worse the financial status of the manufacturer, the more bargaining power suppliers have in determining the contract parameters for more profit.
Radiological and clinical features of multinodular and vacuolating neuronal tumor (MVNT)
Authors: Biyikli Erhan , Kursun Meltem , Altuntas Dogukan , Bayri Yasar , Baltacioglu Feyyaz 
Published: January 2023

Abstract
Background
To investigate the imaging findings and clinical features of multinodular and vacuolating neuronal tumor (MVNT).

Methods
We retrospectively sought for cases that have suspicious imaging findings for MVNT through the hospital information system. The patients’ demographics and clinical symptoms were extracted. All available images were re-examined.

Results
Headache was the most common complaint (n = 7). Other complaints included seizure, stroke-like symptoms and numbness. Conventional MRI revealed that all lesions consisted of tiny, sharply marginated, round or ovoid nodules following the gyral contour. These nodules were hyperintense on T2 and FLAIR WI, hypointense on T1 WI. All lesions were characterized by a lack of enhancement and diffusion restriction. Mass effect and peripheral edema were not observed. MVNT presented as an incidental finding in one case who complained gynecomastia and had pituitary adenoma on pituitary MRI. All lesions were supratentorial—mostly on the right side (10/11)—and located in subcortical white matter. Follow-up MRI was available for 11 patients with a mean of 14.8 months (3–40 months). No change in lesion size and morphology was observed in these follow-up images.

Conclusions
Radiological and clinical follow-up data suggest MVNT may exhibit indolent behavior. If asymptomatic, patients can be followed by imaging alone. Surgery should be considered for symptomatic patients.
Case report: a grievous tale of a rare primary thyroid leiomyosarcoma
Authors: Wan Mansor Wan Nabila , Abdul Gani Norhaslinda , Abu Dahari Khairul Azlan Shahril , Ahmad Aliza , Japar Jaafar Rohaizam 
Published: January 2023

Abstract
Background
Primary thyroid leiomysosarcoma is a rare and aggressive disease which represents 0.014% of primary thyroid cancers. It confers a diagnostic conundrum, due to difficulty to make a preoperative diagnosis of thyroid leiomyosarcoma and to differentiate it from anaplastic thyroid carcinoma.

Case presentation
We herein report a rare case of primary thyroid leiomyosarcoma. A 48-year-old male presented with history of anterior neck swelling for the past 2 months. Computed tomography (CT) neck showed hypodense nodule at the right thyroid lobe with calcification causing tracheal deviation, with intratracheal extension at 1st and 2nd tracheal rings and presence of lung metastases. The histopathology analysis yield high grade spindle cell neoplasm suggestive of sarcoma. Immunohistochemistry showed that neoplastic spindle cells were positive for smooth muscle actin, vimentin, caldesmon while no reactivity was reported for thyroglobulin, calcitonin, thyroid transcription factor-1, S-100, CD45, CD 5, and cytokeratins. Patient had undergone tracheostomy and chemotherapy but he succumbed to death 1 month after completion of chemotherapy.

Conclusion
Primary thyroid leiomyoarcoma is a very rare and aggressive disease. The treatment ranging from surgery, adjuvant radiotherapy and chemotherapy, with high recurrence rates.
Clinical Outcomes After Nonoperative Management of Large Acute Traumatic Subdural Hematomas in Older Patients: A Propensity-Scored Retrospective Analysis
Authors: Kashkoush Ahmed I. , Whiting Benjamin B. , Desai Ansh , Petitt Jordan C. , El-Abtah Mohamed E. , Mcmillan Aubrey , Finocchiaro Roman , Hu Song , Kelly Michael L. 
Published: January 2023

BACKGROUND:
Large (≥1 cm) acute traumatic subdural hematomas (aSDHs) are neurosurgical emergencies. Elderly patients with asymptomatic large aSDHs may benefit from conservative management.

OBJECTIVE:
To investigate inpatient mortality after conservative management of large aSDHs.

METHODS:
Single-center retrospective review of adult patients with traumatic brain injury from 2018 to 2021 revealed 45 large aSDHs that met inclusion criteria. Inpatient outcomes included mortality, length of stay, and discharge disposition. Follow-up data included rate of surgery for chronic SDH progression. Patients with large aSDHs were 2:1 propensity score–matched to patients with small (<1 cm) aSDHs based on age, Injury Severity Scale, Glasgow Coma Scale, and Rotterdam computed tomography scale.

RESULTS:
Median age (78 years), sex (male 52%), and race (Caucasian 91%) were similar between both groups. Inpatient outcomes including length of stay (P = .32), mortality (P = .37), and discharge home (P = .28) were similar between those with small and large aSDHs. On multivariate logistic regression (odds ratio [95% CI]), increased in-hospital mortality was predicted by Injury Severity Scale (1.3 [1.0-1.6]), Rotterdam computed tomography scale 3 to 4 (99.5 [2.1-4754.0), parafalcine (28.3 [1.7-461.7]), tentorial location (196.7 [2.9-13 325.6]), or presence of an intracranial contusion (52.8 [4.0-690.1]). Patients with large aSDHs trended toward higher progression on follow-up computed tomography of the head (36% vs 16%; P = .225) and higher rates of chronic SDH surgery (25% vs 7%; P = .110).

CONCLUSION:
In conservatively managed patients with minimal symptoms and mass effect on computed tomography of the head, increasing SDH size did not contribute to worsened in-hospital mortality or length of stay. Patients with large aSDHs may undergo an initial course of nonoperative management if symptoms and the degree of mass effect are mild.
Reliability of the 44-question Home Fall Hazard Assessment Tool and personal characteristics associated with home hazards among the Thai elderly
Authors: Wittayapun Yuwadee , Nawarat Jiraphat , Lapmanee Sarawut , Mackenzie Lynette , Lektip Charupa 
Published: January 2023

Background: The 44-question Thai Home Fall Hazard Assessment Tool (Thai-HFHAT) was developed to assist healthcare professionals in identifying the risk of falls among community-dwelling elderly from their home environment. However, the reliability of this tool has not been studied. This study aimed to examine reliability of the 44-question Thai-HFHAT and determine the person characteristics associated with home hazards. Methods: A descriptive cross-sectional study design was used for this research. The participants in this study were 51 elderly people from various types of Thai houses: a one-story elevated house, a one-story non-elevated house, and a house with two or more floors, 51 caregivers of elderly patients and 5 village health volunteers (VHV). All participants answered 44 Thai-HFHAT questions to determine inter-rater and test-retest reliabilities. The reliabilities were analyzed using an intra-class correlation coefficient (ICC). Personal characteristics including sex, occupation, and education were used to identify the factors affecting home hazard and linear regression was used to analyze. Results: The ICC of inter-rater reliability of the 44-question Thai-HFHAT was 0.74 (95% CI: 0.57-0.84) and the test-retest reliability was 0.80 (95% CI: 0.64-0.88) for the elderly, 0.80 (95% CI: 0.65-0.89) for the caregivers and 0.70 (95% CI: 0.477-0.83) for the VHV. Personal business career and education level grade 1-3 are less than 0.05, which showed these factors had a significant relationship with the 44-question Thai-HFHAT score as dependent variable. Conclusions: The 44-question Thai-HFHAT is suitable for the home hazards assessment among the elderly in Thailand. Further studies are needed to investigate changes in the house environment after using the 44-question Thai-HFHAT to determine which changes can reduce the risk of fall.
RUSSIAN PROJECT MANAGEMENT SYSTEMS
Authors: Sakhnyuk Tatyana I. , Korshikova Marina V. , Sakhnyuk Pavel A. 
Published: January 2023

In the modern world, it is important for project management to use software products, without which it is difficult to carry out planning and calculations.
This article reviewed Russian project management systems, namely ELMA, Bitrix24, ADVANTA, YouGile
We have reviewed an overview analysis of Russian software, which is excellent for maintaining and implementing project activities. The given advantages of the service and the problems of the work of Russian software products in the field of project management. The proposed software products are most suitable for the implementation of unique projects that are relevant today. The project management systems we have considered will help us use new knowledge in the field of effective project management.
Purpose: acquaintance with Russian software products for project management; provide recommendations on the most effective project management systems.
Method or methodology of the work: the article used empirical research methods.
Results: the best software products for project management were selected.
Scope of the results: these recommendations can be used in the project activities of various organizations, for more successful activities in project management.
DEVELOPMENT AND ADOPTION OF MANAGEMENT DECISIONS IN CHANGE MANAGEMENT (LITERATURE REVIEW)
Authors: Kenina Diana S. , Levushkina Svetlana V. , Svystunova Inna G. 
Published: January 2023

Dynamism and aggressive environmental factors leave no chance for organizations of all types of activities, except to follow modern trends and react flexibly by restructuring their activities and the activities of teams.
Today, managers have a large set of tools and ready-made solutions for implementing changes, but we believe that a list of indicators is needed by which the sequences and methods of transformations will be determined.
Undoubtedly, the institutional framework for making changes in organizations is important, the work contains a list of global organizations that provide both information and consulting and educational support.
The process of reactions and adaptation to changes is quite complicated, as it encounters various obstacles in its path, and the decision-making procedure in such conditions is not simple either.
The article decomposes the process of possible changes, taking into account risk factors and uncertainty, which allows identifying possible barriers and selecting appropriate methods of development and decision-making.
The gamification method is considered as one of the relevant tools for preparing for changes, thanks to which it is possible to simulate new conditions and work out possible staff mistakes, in addition to reveal and develop the creative abilities of employees.
Purpose the study of the features of the development and adoption of managerial decisions in change management.
Methodology the article mainly used the method of theoretical analysis of the available scientific and theoretical base in the field of change management.
Results: the most informative criteria, the need for changes in organizations and the algorithm of development and decision-making in the conditions of transformation of the organization are obtained.
Practical implications it is advisable to apply the obtained results to both management theorists and practitioners in order to improve work in the field of change management.