bluuebunny/crossref_metadata_2025_split huggingface dataset:
The comparison of the efficacy and safety of fractional 1064 nm Nd:YAG picosecond laser and nonablative fractional 1565 nm laser in the treatment of enlarged pores: A prospective split‐face study
Authors: Qian Chunyan , Jiang Yueqi , Wu Yuemeng , Yue Baishuang , Yan Shuxian , Lu Zhong 
Published: January 2023

AbstractBackground and ObjectivesTo compare the efficacy and safety of fractional 1064 nm Nd:YAG picosecond laser and nonablative fractional 1565 nm laser in the treatment of enlarged pores.Study Design/Materials and MethodsTwenty patients received five monthly treatments at months 0, 1, 2, 3, and 4 and were followed up at months 5, 6, and 7. All patients were treated by fractional 1064 nm Nd:YAG picosecond laser (FxPico) on the left face, and nonablative fractional 1565 nm laser (ResurFx) on the right face as a control.ResultsFor the 19 patients who completed the study, both sides demonstrated significant improvement on pore counts (p < 0.01), while there was no significant difference between the two sides 3 months after the final treatment (p = 0.092). Excellence rate on the FxPico side (57.9%) was significantly better than the ResurFx side (36.8%) (p < 0.05). Sebum secretion and porphyrin value significantly decreased on both sides after five treatments and there was a higher reduction of sebum level on the ResurFx side. There was no difference between the two therapies in terms of overall satisfaction. Pain of treatment for the ResurFx side (average VAS 4.45 ± 1.60) is significantly higher than that for the FxPico side (average visual analog scale [VAS] 1.48 ± 1.36) (p < 0.001). Erythema, edema, and petechiae were common adverse effects and were mild to moderate. There was significantly higher incidence of hyperpigmentation for the ResurFx side (52.6%) compared with that for the FxPico side (5.3%) (p < 0.001).ConclusionFractional 1064 nm Nd:YAG picosecond laser and nonablative fractional 1565 nm laser both are effective, efficient, and safe treatment regimens for enlarged pores, while fractional 1064 nm Nd:YAG picosecond laser has better clinical response with less treatment pain, shorter recovery period and much lower induction of hyperpigmentation.
Realization of wide‐angle scanning with tilted beam units and variable radiation subarrays
Authors: Xu Junqing , Xia Yulong , Guo Guangjun , Zhu Qi 
Published: January 2023

AbstractHere, a novel wide‐angle scanning array antenna composed of subarrays with variable radiation patterns is proposed. The subarray consists of two antenna units with tilted beams. With a specially designed feeding network, the phase difference between the antenna units of each subarray keeps the same as that between subarrays. Thus, the radiation pattern of the subarray automatically changes with the array factor. Theoretical analysis shows that the array scanning range can be expanded and the side lobe level (SLL) can be suppressed. A linear array is designed, fabricated, and measured to verify the presented method. The simulated and measured results agree well with each other. The results show that the array can scan from to with gain fluctuation of less than 3 dB and SLL lower than dB.
A dual‐frequency inverted‐F antenna for UAVs transceiver application
Authors: Zhang Rui , Sun Baohua , Qin Dongjie , Li Jianfeng 
Published: January 2023

AbstractA dual‐frequency inverted‐F antenna operating in the ultrahigh frequency band is presented. The proposed antenna includes an inverted F‐shaped radiator and a dual‐frequency loading circuit. The dual‐frequency loading circuit is located between the short pin and the ground. The dual‐frequency loading circuit presents a short‐circuit state at the low‐frequency band and an open‐circuit state at the high‐frequency band. By introducing the dual‐frequency loading circuit, the proposed antenna possesses dual‐frequency performance compared with the traditional inverted‐F antenna. The resonant frequencies of the proposed antenna can be controlled by adjusting the component values of the dual‐frequency loading circuit. A prototype was fabricated and measured to validate the method. The height of the fabricated antenna is 40 mm at 713 MHz. The bandwidths of the fabricated prototype are 713–779 MHz and 858–920 MHz. The proposed antenna possesses vertical polarization, which shows that the proposed antenna has broad application prospects in unmanned aerial vehicles communication systems.
A nonconvex model‐based combined geometric calibration scheme for micro cone‐beam CT with irregular trajectories
Authors: Li Guang , Chen Xue , You Chenyu , Huang Xinhai , Deng Zhenhao , Luo Shouhua 
Published: January 2023

AbstractBackgroundMany dedicated cone‐beam CT (CBCT) systems have irregular scanning trajectories. Compared with the standard CBCT calibration, accurate calibration for CBCT systems with irregular trajectories is a more complex task, since the geometric parameters for each scanning view are variable. Most of the existing calibration methods assume that the intrinsic geometric relationship of the fiducials in the phantom is precisely known, and rarely delve deeper into the issue of whether the phantom accuracy is adapted to the calibration model.PurposeA high‐precision phantom and a highly robust calibration model are interdependent and mutually supportive, and they are both important for calibration accuracy, especially for the high‐resolution CBCT. Therefore, we propose a calibration scheme that considers both accurate phantom measurement and robust geometric calibration.MethodsOur proposed scheme consists of two parts: (1) introducing a measurement model to acquire the accurate intrinsic geometric relationship of the fiducials in the phantom; (2) developing a highly noise‐robust nonconvex model‐based calibration method. The measurement model in the first part is achieved by extending our previous high‐precision geometric calibration model suitable for CBCT with circular trajectories. In the second part, a novel iterative method with optimization constraints based on a back‐projection model is developed to solve the geometric parameters of each view.ResultsThe simulations and real experiments show that the measurement errors of the fiducial ball bearings (BBs) are within the subpixel level. With the help of the geometric relationship of the BBs obtained by our measurement method, the classic calibration method can achieve good calibration based on far fewer BBs. All metrics obtained in simulated experiments as well as in real experiments on Micro CT systems with resolutions of 9 and 4.5 μm show that the proposed calibration method has higher calibration accuracy than the competing classic method. It is particularly worth noting that although our measurement model proves to be very accurate, the classic calibration method based on this measurement model can only achieve good calibration results when the resolution of the measurement system is close to that of the system to be calibrated, but our calibration scheme enables high‐accuracy calibration even when the resolution of the system to be calibrated is twice that of the measurement system.ConclusionsThe proposed combined geometrical calibration scheme does not rely on a phantom with an intricate pattern of fiducials, so it is applicable in Micro CT with high resolution. The two parts of the scheme, the “measurement model” and the “calibration model,” prove to be of high accuracy. The combination of these two models can effectively improve the calibration accuracy, especially in some extreme cases.
Chinesische Schrift‐ und chemische Formelzeichen – eine Gegenüberstellung
Authors: Zhang Baoxin , Börner Armin 
Published: January 2023

AbstractDie chinesischen Schriftzeichen und chemische Formeln sind Symbolsprachen, die auf erzählenden Zeichen basieren. Der Vergleich der beiden zeigt, wie nah sie sich an der Realität orientieren und wie ausbaufähig sie sind. Gleichzeitig wird deutlich: Die chemische Formelsprache ist einzigartig.
Gründer: Methanol und Ethylen aus Kohlendioxid
Authors: Koch Christian 
Published: January 2023

AbstractEnadyne, eine Ausgründung aus der TU Bergakademie Freiberg, erschließt zusammen mit deren Netzwerk aus zwölf Partnern – darunter die Universität Leipzig – einen Synthesepfad für chemische Grundstoffe. Dazu wird CO2 mit einem Wasserstoffträger in einem Plasma umgesetzt.
Auf dem Seziertisch: Wirkstoff‐ Polymer‐Formulierungen
Authors: Pöppler Ann‐Christin 
Published: January 2023

AbstractWie Wirkstoffe mit ihresgleichen oder mit Trägermaterialien interagieren, wenn sie in den menschlichen Körper gelangen, das versucht FCI‐Dozentenpreisträgerin Ann‐Christin Pöppler mit NMR‐Spektroskopie von Festkörpern und Lösungen herauszufinden.
XXXI. Tage der Seltenen Erden in Leipzig
Authors: Kohlmann Holger 
Published: January 2023

AbstractEnde September trafen sich 70 Forscher:innen aus Universitäten, Forschungseinrichtungen und Industrieunternehmen an der Universität Leipzig zur Terra Rarae. Dort berichteten und diskutierten sie über f‐Element‐Verbindungen. Die zweitägige Veranstaltung umfasste 20 Kurz‐ und 4 Plenarvorträge sowie einen Preisvortrag und 25 Posterbeiträge.
Wenn die Low‐Retention‐ Pipettenspitzen fehlen
Authors: Ehrensberger Christian 
Published: January 2023

AbstractAufgrund einer Werksschließung bei 3M in Belgien fällt dieser Lieferant bestimmter Vorprodukte für Pipettenspitzen aus, und zwar speziell für Low‐Retention‐ und Ultra‐Low‐Retention‐Pipettenspitzen. Labore, die sie brauchen, haben ein Problem – für das es bereits Lösungsansätze gibt.
Regionales FCI‐Stipendiatentreffen in Würzburg
Authors: Meier Lukas 
Published: January 2023

AbstractEnde September trafen sich die Stipendiaten des Fonds der Chemischen Industrie (FCI) an der Universität Würzburg (JMU). Die Organisation übernahm Holger Braunschweig, Professor für anorganische Chemie, gemeinsam mit den in Würzburg ansässigen Stipendiaten. Bei der Veranstaltung kamen elf Nachwuchswissenschaftler zusammen, die durch ein Kekulé‐Stipendium gefördert werden, und präsentierten ihre Forschungsergebnisse.
Kreativität ein Leben lang
Authors: Wille Eva 
Published: January 2023

AbstractEin sehr ungewöhnliches Arbeitswochenende vom 30. September bis 2. Oktober über den Dächern von Freiburg zeigte eindrücklich, dass „Kreativität ein Leben lang“ in der Chemie möglich ist. Fünf Autobiografien von außerordentlich kreativen Chemikern sind seit September 2021 in der Reihe „Lives in Chemistry / Lebenswerke in der Chemie“ erschienen (herausgegeben von der GDCh‐Fachgruppe Geschichte der Chemie). Es ist also ein guter Zeitpunkt für einen Gedankenaustausch zwischen den Mitgliedern des Beirats und Autoren sowie mit Lesern. Auf Einladung des Initiators und Förderers der Reihe, Karl Reuter von der Firma RCA Freiburg, lernten sich über 30 Chemiker im Alter von 17 bis 92 Jahren kennen und diskutierten über „den kreativen Prozess“.
Experiences of healthcare workers following occupational exposure to COVID‐19 at the early stages of the pandemic: A phenomenological qualitative study
Authors: Wang Qun , He Peiqin , Tian Yu , Zhu Yimin , Qin Yuelan , Qiu Xiaoying , Liu Yanhui , Xu Xiaoping , Hu Wanqin , Shi Zeya 
Published: January 2023

AbstractAimTo explore the experiences of healthcare workers (HCWs) following occupational exposure to coronavirus disease 2019 (COVID‐19) during the early stage of the pandemic.DesignA Husserl descriptive phenomenological study design was employed.MethodsConvenient and snowball sampling was used. In‐depth semi‐structured telephone interviews were conducted from February to March 2020 with the frontline HCWs who were exposed to COVID‐19 during work. Data analysis was conducted following the 7‐step analysis method developed by Colaizzi.ResultsFifteen HCWs participated in the study. Four themes were identified, including (1) traumatic experiences since the occupational exposure; (2) getting through the hard time; (3) struggling to return to work; (4) reflections on occupational exposures.ConclusionThe HCWs had traumatic and painful experiences after the occupational exposure. But they returned to work with strong resilience, professional obligation and social support. Training and supervision, and adequate supply of personal protective equipment are suggested to prevent professional exposure. Social and organizational support should be provided for the exposed HCWs.
Qualitative Assessment of Quality and Readability of Patient‐Directed Online Resources for Cochlear Implants in Children
Authors: Sanad Saad A. , Mokhtar Aseel M. , Alharbi Manar O. , Bukhari Afnan F. , Zawawi Faisal 
Published: January 2023

AbstractObjectiveChildren with sensorineural hearing loss can benefit from cochlear implantation (CI). Patients can obtain direct access to medical information on the internet. However, the internet is uncontrolled, and the quality and readability of information are unpredictable. The quality and readability of websites providing information about CI in children were assessed in this study.Study DesignCross‐sectional study.SettingOnline search.MethodsThe 3 most popular search engines (Google, Bing, and Yahoo) were queried with the phrases “cochlear implant” and “cochlear implant in children.” The DISCERN instrument was used to assess the information quality. The readability was evaluated using 5 validated readability indices.ResultsOf 103 websites, the median DISCERN quality score was 33 (interquartile range [IQR], 27‐41). Only 5 websites were considered to be of good quality, and 1 was excellent. The median readability school grade was 11th (IQR, 10‐12), which fell within the range defined as difficult. No website was at or below the recommended sixth‐grade level. There was no correlation between readability and the DISCERN scores (r = −0.105, p = .291).ConclusionOur study suggests that most websites with information on CI for children are of variable quality and are written beyond the reading ability of the general population. Website builders should focus on improving the readability of their online material to help the average reader understand and benefit from the content.
Algorithmic Identification of Patients With Aspirin‐Exacerbated Respiratory Disease Using an Electronic Health Record
Authors: Tao Michael , Roberts Sarah , Arnold Mark 
Published: January 2023

AbstractObjectiveTo determine whether an electronic health record (EHR) system can be used to identify cases of aspirin‐exacerbated respiratory disease (AERD) in an area outside of a regional referral center with low rates of aspirin desensitization therapy.Study DesignRetrospective chart review single academic tertiary care hospital.SettingSingle‐site academic tertiary care hospital.MethodsUsing Epic's SlicerDicer function, an algorithm was created and applied to all patient charts from 2013 to 2021. The algorithm was as follows: “Allergy/Contraindication to NSAIDs OR aspirin” AND “Diagnosis of Nasal polyp AND “Diagnosis of Asthma.” Clinical data including demographics, NSAID reaction, and specialist involvement was collected.ResultsA total of 54 potential cases of AERD were identified. Thirty‐two were determined to have AERD after chart review, yet 12 of these patients (37.5%) had no mention of AERD within the chart. The 54 patients were stratified into 2 cohorts based on reaction to NSAIDs: respiratory (n = 29) or unspecified (n = 25). Of the patients in the respiratory reaction group, 26 were found to have clinical AERD, demonstrating a positive predictive values (PPV) of 89.7%. The overall PPV was 59.3%. Those with a respiratory reaction to NSAIDS listed in the EHR were more likely to have clinical AERD (odds ratio 27.44; confidence interval 6.08‐123.85; p < 0.0001). Only 2 patients (6.3%) underwent aspirin desensitization.ConclusionAERD remains under‐diagnosed in the study population. The informatics algorithm presented here has a high positive predictive value for identifying clinical AERD patients in a geographical area with low rates of aspirin desensitization and may aid in identifying candidates for expanded treatment options.
The effect of fiber orientation and stacking sequence on carbon/Kevlar/epoxy intraply hybrid composites under dynamic loading conditions
Authors: Samson P. Edwin , Kumaran S. Senthil , Shanmugam Vigneshwaran , Das Oisik 
Published: January 2023

AbstractThis work investigated the thermo‐mechanical behavior of (carbon/Kevlar) intraply hybrid composites. The carbon/Kevlar plies' orientation and sequential arrangement were varied. Carbon and Kevlar composites, as well as five different intraply hybrids (HFRPs) composite such as carbon‐0°/Kevlar‐90°, carbon‐45°/Kevlar‐135°, carbon‐90°/Kevlar‐0°, carbon/Kevlar (inter‐changing layer), and carbon/Kevlar‐45° (inter‐changing layer) composites, and a plain epoxy panel, have been developed. The thermo‐mechanical characteristics of the fabricated composites were estimated using a dynamic automated analyzer under changing mechanical and thermal load conditions. The DMA technique measured the HFRPs composite visco‐elastic parameters by increasing the temperature from 30°C to 150°C at frequencies ranging from 1 to 20 Hz. Flexural test characteristics for neat epoxy, carbon fiber‐reinforced composites, Kevlar fiber‐reinforced composites, and carbon/Kevlar fiber‐reinforced composites were estimated to aid the study. The experimentally measured versus analytically calculated viscoelastic parameters were related. The results revealed that carbon‐90° oriented in warp direction/Kevlar‐0° oriented in weft direction exhibited higher modulus and lower loss tangent followed by carbon/Kevlar plies oriented in alternate layers and carbon/Kevlar plies oriented in inter‐changing layers at 45°. Carbon‐0° introduced in the weft direction/ Kevlar‐90° introduced in the warp direction, and carbon‐45°/Kevlar‐135° exhibited intermediate storage and loss modulus and a moderate loss tangent at the various frequency levels considered in the study.
Validity of the Childhood Asthma Control Test in diverse populations: A systematic review
Authors: Chu Francesca , Kappel Nicole , Akel Mary , Press Valerie G. , Alexander Jason T. , Volerman Anna 
Published: January 2023

AbstractPurposeWe examined the validity of the Childhood Asthma Control Test (C‐ACT) and identified recommended thresholds for uncontrolled asthma in children from varying backgrounds.MethodsA systematic literature review was performed utilizing PubMed, Ovid Medline, SCOPUS, CINAHL, and conference proceedings. Studies were included if they enrolled children, had a primary outcome of asthma control, examined test validity or psychometrics, and utilized the C‐ACT. Along with study design and demographic data, we extracted all outcomes and comparisons used to validate the C‐ACT. We evaluated risk of bias using the COSMIN Risk of Bias tool. Our protocol was registered with PROSPERO (CRD42020211119).ResultsOf 4924 records screened, 28 studies were included. Studies were conducted internationally and published between 2007 and 2018. Average number of enrolled participants was 193 (SD = 155, range = 22–671). Ten studies calculated Cronbach's α (mean [SD] = 0.78(0.05), range = 0.677–0.83). Thirteen studies recommended cut‐offs for uncontrolled asthma (≤18–≤24). Nine studies found significant agreement or correlation between C‐ACT and Global Initiative for Asthma guidelines/physician assessment of asthma control (correlation coefficients range = 0.219–0.65). Correlation coefficients between C‐ACT and spirometry were <0.6 in five of six studies that included spirometry. Kappa values for C‐ACT and various spirometry measurements ranged 0.00–0.34.ConclusionsThe C‐ACT showed good internal consistency and mixed levels of agreement and correlation with various clinical asthma measures. Recommended cut‐offs for asthma control varied and had no consistent relationship with nationality, race, ethnicity, or language. Few studies examined cross‐cultural validity and multiple populations remain under‐studied.
Relativistic Wormholes in Extended Teleparallel Gravity with Minimal Matter Coupling
Authors: Mustafa G. , Maurya S. K. , Hussain Ibrar 
Published: January 2023

AbstractThis study explores the wormhole solutions utilizing the notion of conformal symmetry in the background of the gravity. The exact shape functions are calculated using the Gaussian and Lorentzian distributions as the noncommutative source of the energy density. All the energy conditions are checked for the two different shape functions. The presence of exotic matter is confirmed due to the violation of the null energy conditions. The physical aspects of the epicyclic frequencies of test particles are discussed in the spacetime geometry of the obtained wormholes in the current analysis and it is shown that how they depend on the spacetime parameters. The red‐blue shifts for the photons emitted by the orbiting test particles are also investigated and their dependence on the spacetime parameters is discussed. Further, the stability of the developed structure of the traversable wormholes is investigated by using the Tolman‐Oppenheimer‐Volkoff equation.
Salvage stereotactic body radiation therapy for locally recurrent prostate cancer following primary radiation therapy, are benefits worth toxicity risks?: A systematic review
Authors: Bray Gerard , Bahadori Arya , Rama Darren 
Published: January 2023

AbstractIntroductionSalvage stereotactic body radiation therapy (SBRT) for localized prostate cancer recurrence following radiation therapy remains controversial. We performed a systematic review to assess the efficacy and side effect profile of salvage SBRT for locally recurrent prostate cancer to define the role of salvage SBRT in clinical practice.MethodsA systematic review was carried out using Pubmed (MEDLINE) and Scopus databases. Inclusion and exclusion criteria were satisfied if studies reported on patients with prior radiation therapy for prostate cancer who had subsequently had a local recurrence. Those studies included were quality assessed using the ROBINS‐I checklist.ResultsFive studies in total met criteria for inclusion and included all reportable outcomes. A total of 265 participants are reported on in total. Median doses for SBRT ranged from 30 to 36 Gy delivered over 5−6 fractions. Recurrence free survival ranged from 40% to 76% at 2 years. Genitourinary toxicity was more prevalent than gastrointestinal toxicities. Grade 2 and 3 genitourinary complication rates ranged from 5% to 22% and 0% to 9%, respectively. Gastrointestinal grade 2 complication rates ranged from 0% to 11% and no grade 3 complications were recorded.DiscussionSalvage SBRT appears to be comparable and potentially superior in some aspects to other salvage therapies, taking into account the limitations in cross‐study comparisons. This systematic review serves as one of the first to characterize SBRT as a salvage option for locally recurrent prostate cancer.
Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis
Authors: Yang Yuanyuan , Chen Yanmei , Wu Jun Hao , Ren Yueting , Liu Bo , Zhang Yan , Yu Haiyang 
Published: January 2023

AbstractRegulated cell death (RCD) refers to programmed cell death regulated by various protein molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis. Accumulating evidence has recently revealed that RCD subroutines have several links to many types of human cancer; therefore, targeting RCD with pharmacological small‐molecule compounds would be a promising therapeutic strategy. Moreover, plant natural compounds, small‐molecule compounds synthesized from plant sources, and their derivatives have been widely reported to regulate different RCD subroutines to improve potential cancer therapy. Thus, in this review, we focus on updating the intricate mechanisms of apoptosis, autophagy‐dependent cell death, and necroptosis in cancer. Moreover, we further discuss several representative plant natural compounds and their derivatives that regulate the above‐mentioned three subroutines of RCD, and their potential as candidate small‐molecule drugs for the future cancer treatment.