bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peripheral and central olfactory measurements in Chronic Obstructive Pulmonary Disease patients
Authors: Sarikaya Pelin Zeynep Bekin , Muluk Nuray Bayar , Göncüoğlu Alper , Özdemir Adnan , Ekici Aydanur 
Published: July 2023

Abstract

OBJECTIVES. We investigated peripheric and central olfactory pathways on MRI in Chronic Obstructive Pulmonary Disease (COPD) patients and the relationship between olfactory measurements of COPD patients and thorax CT images of emphysema classification in them.

MATERIAL AND METHODS. In this retrospective study, cranial MRI of 42 adult patients with COPD and 42 healthy adults without COPD were included. In both groups, peripheral (olfactory bulb (OB) volume and olfactory sulcus (OS) depth) and central olfactory areas (insular gyrus and corpus amygdala areas) were evaluated. We classified thorax CT findings according to emphysema by size as 1 to 4.

RESULTS. In the present study, left OB volume of the COPD group was significantly lower than that in the control group (p<0.05). On the right side, there were no significant differences between OB volumes of the COPD and control groups. Although right OB volume values were found to decrease proportionally, they were not found to be statistically significant. Also, insular gyrus and corpus amygdala areas of the COPD group were significantly lower than those in the control group, bilaterally (p<0.05). OS depths of the COPD group were significantly higher than those in the control group, bilaterally (p<0.05). In males, the right OB volume values were higher than those in females (p<0.05).

CONCLUSION. In COPD patients, left OB volumes decrease and OS depths increase bilaterally, and central areas decrease bilaterally, regardless of the thoracic emphysema classification. It may be related to hypoxemia that causes airway inflammation; inflammatory mediators may be harmful to the olfactory neuroepithelium.
Optimasi digesti enzim restriksi untuk deteksi mutasi daerah D-loop DNA mitokondria dengan metode PCR-RFLP
Authors: Septiasari Ni Putu Senshi , Junitha I Ketut , Wirasiti Ni Nyoman 
Published: July 2023

Metode PCR-RFLP merupakan salah satu metode untuk deteksi mutasi pada daerah D-loop DNA mitokondria. Metode ini menggunakan enzim restriksi untuk dapat memotong DNA mitokondria dan menghasilkan ukuran fragmen DNA yang berbeda-beda. Enzim restriksi memerlukan kondisi yang optimal untuk melakukan pemotongan DNA. Penelitian ini bertujuan untuk mengetahui kondisi optimal enzim restriksi agar dapat melakukan digesti pada daerah D-loop DNA mitokondria. Optimasi dilakukan dengan membuat dua kombinasi formula digesti (formula 1 dan 2) dan empat macam waktu digesti (2 jam, 4 jam, 6 jam dan overnight). Hasil penelitian menunjukkan optimasi dari lima macam enzim restriksi (HaeIII (BsuRI), HindIII, HinfI, MboI dan HpyP31 (DdeI)) didapatkan bahwa ada perbedaan formula dan waktu digesti tergantung dari jenis enzim. Enzim HaeIII(BsuRI), HinfI dan MboI menunjukkan formula 2 merupakan formula optimal, sedangkan enzim HpyP31 (DdeI) formula 1 merupakan formula yang optimal. Waktu digesti 2 jam menunjukkan hasil optimal pada Enzim HaeIII(BsuRI), MboI dan HpyP31 (DdeI), sedangkan enzim HinfI waktu digesti optimal adalah 4 jam. Enzim HindIII tidak mendapatkan hasil potongan fragmen DNA setelah digesti, maka enzim HindIII tidak memiliki situs pemotongan pada daerah D-loop DNA mitokondria.
DEVELOPMENT OF AN EXPRESS METHOD FOR DETERMINING IODINE NUMBER AND CONTENT OF ω-3 FATTY ACIDS RESIDUES IN VEGETABLE OILS
Authors: КРАПИВИН Г.Д. , СТРОГАНОВА Т.А. , ВАСИЛИН В.К. 
Published: July 2023

Изучен качественный и количественный состав нескольких образцов масел и жиров мето- дом спектроскопии ядерного магнитного резонанса (ЯМР-спектроскопии). Предложен экспресс-метод оп- ределения степени ненасыщенности, йодногочисла и содержания ω-3 кислот с использованием техни- ки ЯМР. Для апробации проведены контрольные измерения указанных величин для исследуемых образцов методами, предусмотренными ГОСТ. Продемонстрировано, что метод ЯМР-спектроскопии позволяет как с доста- точной точностью определять степень ненасыщенности масел и жиров, а следовательно, и величину йодного чи- сла, так и достоверно и количественно устанавливать процентное содержание остатков ω-3 карбоновых кислот.
The qualitative and quantitative composition of several samples of oils and fats was studied by nuclear magnetic resonance spectroscopy (NMR spectroscopy). An express method for determining the degree of unsaturation, iodine number and content of ω-3 acids using NMR techniques is proposed. For approbation, control measurements of the indicated values for the test samples were carried out using the methods provided for by GOST. It has been demonstrated that the NMR spectroscopy method makes it possible both to determine with sufficient accuracy the degree of unsaturation of oils and fats, and hence the iodine number, and to reliably and quantitatively determine the percentage of ω-3 residuesof carboxylic acids.
EVALUATION OF THE ECONOMIC EFFICIENCY OF THE PRODUCTION TECHNOLOGY OF ICE-CREAM FROM MARE’S MILK WITH ADDITION OF POLYSACCHARIDES
Authors: САУКЕНОВА М.М. , НУРГАЛИЕВА Б.М. , БЕЛОГЛАЗОВА К.Е. , РЫСМУХАМБЕТОВА Г.Е. , УШАКОВА Ю.В. 
Published: July 2023

Рассчитана экономическая эффективность внедрения в производство мороженого из кобыльего молока с до- бавлением полисахаридов (ПС). Установлено, что по органолептическим показателям мороженое из кобыльего молока с добавлением ПС не уступаеттрадиционному из коровьего молока, что позволяет расширить ассортимент продуктов специализированного назначения. Для повышениякачества выпускаемого продукта на всех технологических этапах – от приемки сырья до хранения и транспортировки готовой продукции – разработана блок-схема производства моро- женого с указанием контрольных критических точек (ККТ). Подобрана линия производствастоимостью 5676 тыс. р. По результатам экономических расчетов прибыль составит 35070,26 тыс. р. при годовой производственноймощности 511,85 т. Проведенные расчеты подтвердили, что данная разработка не только является перспективной с точки зрения получения прибыли, но и позволяет создать новые здоровьесберегающие технологии для широких слоев населения.
The economic efficiency of introducing into the production of ice cream from mare’s milk with the addition of polysaccharides (PS) is calculated. It has been established that, in terms of organoleptic parameters, mare’s milk ice cream with the addition of PS is not inferior to traditional cow’s milk ice cream, which makes it possible to expand the range of specialized products. To improve the quality of the manufactured product at all technological stages – from the acceptance of raw materials to the storage and transportation of finished products – a blockdiagram of the production of ice cream has been developed, indicating control critical points (CCP). A production line worth 5676 thousandrubles was selected. Based on the results of economic calculations, the profit will amount to 35,070,26 thousand rubles. with an annual productioncapacity of 51,185 tons. Calculations have confirmed that this development is not only promising in terms of making a profit, but also allows you to create new health-saving technologies for the general population.
PENGARUH TRANSPLANTASI SEL PUNCA MESENKIMAL TERHADAP PERJALANAN PENYAKIT ALZHEIMER BERBASIS PENELITIAN PADA TIKUS: SEBUAH TINJAUAN SISTEMATIS
Authors: Firsty Naufal Nandita , Nadilah Devi , Aritonang Ilman Arif 
Published: July 2023

Penyakit Alzheimer atau Alzheimer’ s disease (AD) merupakan salah satu penyakit neurodegeneratif yang paling umum didiagnosis pada populasi dunia, terkhusus pada wanita. Beberapa manifestasi patologi yang dapat diobservasi adalah deposisi beta-amyloid (Aβ), hiperfosforilasi protein tau, dan inflamasi yang ketiganya berperan sebagai core-pathology dari AD. Permasalahan terberat dari terapi AD saat ini adalah ketidakmampuan berbagai agen farmakologis saat ini untuk menghentikan progresivitas AD. Oleh karena itu, salah satu ikon terapi medis modern yaitu terapi sel punca atau stem cell (SC), khususnya menggunakan sel punca mesenkimal atau mesenchymal SC (MSCs) pada beberapa tahun terakhir telah dijadikan sebagai salah satu fokus studi terapi kuratif penyakit degeneratif yang selama ini hampir selalu tidak mungkin tercapai. Manuskrip tinjauan sistematis ini bertujuan untuk menjabarkan pengaruh transplantasi MSCs secara xenogenik maupun alogenik pada berbagai spesies tikus yang telah diinduksi dengan Aβ untuk mengalami kondisi AD buatan yang dilaporkan oleh berbagai penelitian orisinal pada beberapa tahun terakhir. Sebanyak 32 penelitian dijadikan sebagai referensi utama yang keseluruhannya menunjukkan perbaikan perihal manifestasi patologis seperti reduksi dari deposisi Aβ, penurunan kondisi inflamasi melalui berbagai biomarka, peningkatan aktivitas neurogenesis pada beberapa regio otak seperti hipokampus, dan efek neuroproteksi yang cukup signifikan. Pengaruh tersebut juga dapat diobservasi pada kondisi tingkah laku (behavior) tikus percobaan seperti perbaikan fungsi kognitif dan memori yang diukur berdasarkan metode observasi tertentu. Oleh karena itu, MSCs diduga memiliki potensi untuk menjadi sebuah terapi kuratif bagi AD yang selama ini tidak mampu menghentikan progresivitasnya.
Innovation and Organizational Culture in South American Companies in the Last Decade
Authors: Peve Tamara Geraldine Villanueva , Cochachin Fiorella Lesly Urbano , Patilla Aracely Keyla Torres , Quispe Jimmy Alberth Deza 
Published: July 2023

Purpose: The current analysis aimed to review the state-of-the-art about innovation and organizational culture in enterprises placed or working in South America.

Theoretical Framework: Innovation and organizational culture are critical concepts in management studies nowadays. In South America, in recent years, companies have had the trend to disrupt static and hierarchized organizations by allowing employees to participate actively in the organization's objectives. Moreover, flexible companies do not mean that hierarchies do not exist. Instead, it means that companies are eager to listen and accept the different points of view of the employees. Moreover, innovative companies seem to adapt rapidly to both beneficial and adverse environments. However, some firms resist changes and get revenues, but the evidence suggests that they put their sustainability in the long term.

Design/Methodology/Approach: In consequence, the methodological approach was the employment of the PRISM method to depurate the initial bibliographic resources from EBSCO and RENATI. EBSCO was used to analyze papers, and RENATI to review theses. Initially, there were 78 articles and 271 theses to be examined. After the PRISM depuration, it was analyzed 35 papers and theses from the period lasting from 2012 to 2021.

Findings: The results showed that flexible companies were more adaptative than rigid ones. Moreover, the literature suggested that flexible companies have more chances to be sustainable in the long term than other firms. Therefore, it is possible to state that innovation policies had a higher impact in flexible organizations than in rigid ones.

Originality/Value: The value of the study relies on the systematic review of the current literature of innovation and organizational culture in South America which is the nearest international environment for Peruvian companies.
The Effect of Human Resources Practices on Sport Organization’s Performance in Oman: The Mediating Role of Leadership Style
Authors: Al Balushi Isehaq Ahmed Abdullah , Muslim Noor Awanis , Khudari Mohamed 
Published: July 2023

Purpose: This paper examines the impact of human resource management (HRM) practices on organizational performance, with mediating role of leadership style.

Theoretical framework: This study integrates theoretical perspectives on HRM practices Namely (the recruitment selection process, incentive system, and training & development), Leadership style and organisational performance. The conceptual model for this study was developed based on previous research in the field of HRM practices and leadership styles globally. The conceptual model has HRM practices as an independent variable (IV), Leadership style as a mediator and organisational performance as a dependent variable (DV).

Design/Methodology/Approach: A survey questionnaire instrument was employed to collect data from 156 employees working at sport organisations in Oman. SPSS was used for analysing the data, and Smart-PLS were used to test the proposed hypotheses.

Findings: The result revealed that human resource practices are significantly related to organisational performance. Also, leadership styles mediated the influence of HRM practises on organisational performance.

Research, practical & social implications: The finding of this study provides valuable insights into sport organisations in Oman can enhance their HRM practices to improve organisational performance and achieve their goals. Moreover, it has been recommended that organizations use a leadership style that enhances organizational performance. The results come from a cross-sectional study which was done at the convenience of the researcher. The results may not be generalized across the country. The application of the results to other organisations must be done with maximum care.

Originality/Value: This study adds to the literature on the effectiveness of HRM practices, Leadership style in enhancing organisational performance in a specific context namely the sport organisations in Oman. The study also highlights the mediating role of leadership style in the relationship between HRM practices and organisational performance.
The Relationship Between Financial Development and Carbon Emissions: A Systematic Review
Authors: Darweesh Feras , Khudari Mohamed , Othman Nor Salwati 
Published: July 2023

Purpose: This paper aims to review and analyze the prior research on the relationship between financial development and carbon emissions. As the financial sector develops and the economies grow, carbon emissions are expected to increase. Therefore, it is necessary to identify and understand the factors that contribute to this relationship.

Theoretical framework: Recent studies indicate that financial development facilitates and expands businesses, which may cause an increase in carbon emissions; on the other hand, sustainable development of the financial sector may lead to lower carbon emissions through eco-friendly investments.

Design/Methodology/Approach: This study will employ a systematic literature review to investigate the relationship between financial development and carbon emissions and analyze how developing and developed countries differ concerning these two factors.

Findings: The result showed that empirical studies have produced various, frequently contradicting findings and conclusions. Some studies show a strong positive correlation between financial development, environmental performance indices, and economic growth, while others find a more nuanced correlation.

Research, practical & social implications: This study might stimulate additional investigation into green financial development and emission reductions through green investments. Findings could aid in adjusting policies to account for disparities between developed and developing countries' financial-emission relationships. Green financial instruments might encourage eco-investments and reduce emissions. The social advantages include helping to reduce gaps by providing resources and expertise to poorer nations, promoting sustainability, and contributing to climate solutions.

Originality/Value: This research thoroughly assesses and analyzes prior research on the relationship between financial development and carbon emissions. Particularly in the context of developed and emerging countries, the study helps to investigate and comprehend the elements contributing to this relationship.
Importance of Electronic Accounting Information Systems in Improving Financial Information Security in Jordanian Electronic Payment and Money Transfer Companies
Authors: Al-Khasawneh Reem Oqab 
Published: July 2023

Purpose: The study aimed to assess the level of effectiveness of electronic accounting information systems in enhancing the security and control of financial information in Jordanian payment and electronic transfer companies and its ability to provide reliability. And analyzing the ability of the system used in the payment and financial transfer companies to meet the operational requirements imposed by the regulators of the sector.

Theoretical framework: The theoretical framework dealt with the topics of the study from the security threats of electronic accounting information systems (Jacob, 2012: 67) and the risks of accounting information systems that are related to electronic payment systems, especially information security (Al-Maghribi, 2017). Accounting in reducing the risks of transactions, and the obstacles facing accounting systems in the face of the risks and threats of electronic systems

Design/Methodology/Approach: The researcher used the inductive approach by referring to the literature related to the subjects of the study and the deductive approach in the field study by distributing a questionnaire to the electronic payment companies in Jordan. 96 questionnaires were retrieved. Using the spss program to analyze the data and reach the results

Findings: The study Fined that there are factors that help to penetrate the accounting information systems in the Jordanian electronic payment and financial transfer companies. Network communication. Electronic accounting information in enhancing the security of financial information and control over it, and there are (obstacles) in providing security requirements and information control, in electronic payment and financial transfer companies related to the rapid development of electronic financial systems and electronic payment methods and their development.

Research, practical & social implications: This study is considered one of the important and modern topics because electronic payment processes are considered one of the modern concepts with which many risks are associated. This study sheds light on these risks and threats and the ability of the strong accounting system to confront these threats and risks..

Originality/Value: The results indicate the importance of the topic and the importance of conducting a study on the risks of electronic payment systems, the threats facing the use of electronic payment methods and the obstacles facing accounting information systems in one of the newly established economic sectors in Jordan, which is the electronic payment companies.
Prototipe Chromameter untuk Deteksi Bumper Berbasis Raspberry Pi-4 dan Sensor AS7341
Authors: ANAM FAJAR CHOIRUL , SAMSURI FAISAL , SIMATUPANG JONI WELMAN 
Published: July 2023

ABSTRAKAda kebutuhan untuk peningkatan kualitas kontrol pengecekan akurasi warna bumper yang diproduksi di PT. Sugity Creatives. Kebutuhan ini disebabkan oleh berbagai pekerjaan repetitif, tidak efisien, dan relatif lama. Sesuai pengamatan, pengecekan membutuhkan waktu 45 detik, validasi data manual selama 15 detik dan pencatatan di kertas selama 60 detik. Sehingga total proses adalah 120 detik. Di artikel ini, kami mengusulkan sebuah prototipe menggunakan Konica Minolta CR400 chromameter. Prototipe ini terdiri dari dua komponen utama yaitu Raspberry Pi-4 sebagai pengontrol dan penyimpan data, dan sensor spektrometri AS7341 untuk mengukur spektrum bumper setelah selesai dilakukan pengecatan. Berdasarkan hasil pengujian, prototipe mampu mereduksi waktu inspeksi kualitas dari 120 detik menjadi 40 detik, termasuk pengukuran, validasi warna, dan juga pencatatan di spreadsheet. Validasi juga memiliki akurasi 100% sesuai dengan hasil validasi chromameter CR400 setelah prototipe dikalibrasi dengan sampel bagus dan reject. Namun, risiko kesalahan manusia selama perekaman data menyebabkan kesalahan validasi mungkin tidak dapat dihindari.Kata kunci: Raspberry Pi-4, AS7341, Chromameter, Spektrometri, Sensor ABSTRACTThere is a need to improve the quality control process efficiency for bumper color accuracy checking at Sugity Creative Companies. This need caused by several repetitives, inefficient, and relatively working time. As we observed, there is 45 seconds for checking process, 15 seconds for manual validation, and 60 seconds for data writing on paper. Thus, total processing time is 120 seconds. In this paper, we propose an improvement through a prototype using Konica Minolta CR400 chromameter. This prototype consists of two main components, namely Raspberry Pi-4 as controller and storage, and AS7341 spectrometry sensor for measuring the spectrum of the bumper color after being painted. According to our experimental result, prototype can reduce the inspection quality time from 120 to 40 seconds over the measurement, color validation, and data recording in the spreadsheet. Validation also has 100% accuracy compared to the CR400 chromameter after it is calibrated to the good and rejected samples. Moreover, the human error risk during the data recording caused the validation error is might inevitable.Keyword: Raspberry Pi-4, AS7341, Chromameter, Spectrometry, Sensor
Analysis of Gray Matter Volume (GMV) and White Matter Hyperintensity (WMH) in Ischemic Stroke Patients with Fluid Attenuated Inversion Recovery (FLAIR) Imaging
Authors: Fadlilah Ade Lina Nur , Noor Johan Andoyo Effendi , Yueniwati Yuyun , Karimah  
Published: July 2023

Stroke is a serious health problem faced by almost all over the world. The occurrence of ischemic stroke could affect the gray matter volume (GMV) in the human brain. In Magnetic Resonance imaging of an ischemic stroke with a FLAIR sequence, a white lesion known as the white matter hyperintensity (WMH) is often found. We studied correlation between gray matter volume (GMV) and white matter hyperintensity (WMH) in ischemic stroke patients using fluid attenuated inversion recovery (FLAIR) sequences. The MRI data were taken randomly from ten ischemic stroke patients (mean age 46.9 years) and ten normal patients (mean age 36.8 years). FLAIR axial image parameters, i.e. TE (time echo), TR (time repetition), and TI (time inversion) were analyzed. The results reveal that the TE and TR values in FLAIR images of normal and ischemic stroke patients are classified as long TE (more than 70 ms), long TR (more than 1500 ms) and long TI (more than 1700 ms). The mean GMV of ischemic stroke patients (1.371 cm3) is smaller than the GMV of normal patients (2.267 cm3). This is related to the presence of white matter hyperintensity (WMH) in ischemic stroke patients
Potency of Secondary Metabolites from Salacca zalacca, Sonchus arvensis, and Carica papaya against Aedes aegypti L.
Authors: Astuti Raden Roro Upiek Ngesti Wibawaning , Illahi Auliya Nur , Umri Wali Nasir Saddiqi , Falah Afghan Azka 
Published: July 2023

Dengue infection is still as a major public health in the world including Indonesia, wherein from January to June showed about 45,387 cases and 432 deaths. There are many prevention and control activities that have been carried out but have not given contented results despite using insecticides. Plants secondary metabolites are confirmed have biological activity and can protecting the plants from an insect pest and diseases. This study proposed that secondary metabolites in several plants have the potential as biolarvicide. This study aimed to determine the potency of secondary metabolites in Salacca zalacca, Sonchus arvensis, and Carica papaya as biolarvicide. Each extract was test in five concentrations of treatment and two controls, negative control using aquadest and positive control using temephos 1%. The third instar larvae of Ae. aegypti mosquito were used in biolarvicide test, with 10 larvae for each treatment and 3 replications for 24 hours. This study revealed that C. papaya extract showed the highest potency as biolarvicide compared to S. zalacca and S. arvensis. The LC50 and LC90 for 24 hours of C. papaya extract were 2.62% and 5.49% respectively.