bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal 18F-FDG PET/CT radiomics model development for predicting EGFR mutation status and prognosis in lung adenocarcinoma: a multicentric study
Authors: Zuo Yan , Liu Qiufang , Li Nan , Li Panli , Zhang Jianping , Song Shaoli 
Published: May 2023

PurposeTo develop and interpret optimal predictive models to identify epidermal growth factor receptor (EGFR) mutation status and subtypes in patients with lung adenocarcinoma based on multicentric 18F-FDG PET/CT data, and further construct a prognostic model to predict their clinical outcome.MethodsThe 18F-FDG PET/CT imaging and clinical characters of 767 patients with lung adenocarcinoma from 4 cohorts were collected. Seventy-six radiomics candidates using cross-combination method to identity EGFR mutation status and subtypes were built. Further, Shapley additive explanations and local interpretable model-agnostic explanations were used for optimal models’ interpretation. Moreover, in order to predict the overall survival, a multivariate Cox proportional hazard model based on handcrafted radiomics features and clinical characteristics was constructed. The predictive performance and clinical net benefit of the models were evaluated via area under receiver operating characteristic (AUC), C-index and decision curve analysis. ResultsAmong the 76 radiomics candidates, light gradient boosting machine classifier (LGBM) combined with recursive feature elimination wrapped LGBM feature selection method achieved best performance in predicting EGFR mutation status (AUC reached 0.80, 0.61, 0.71 in the internal test cohort and two external test cohorts, respectively). And extreme gradient boosting classifier combined with support vector machine feature selection method achieved best performance in predicting EGFR subtypes (AUC reached 0.76, 0.63, 0.61 in the internal test cohort and two external test cohorts, respectively). The C-index of the Cox proportional hazard model achieved 0.863.ConclusionsThe integration of cross-combination method and the external validation from multi-center data achieved a good prediction and generalization performance in predicting EGFR mutation status and its subtypes. The combination of handcrafted radiomics features and clinical factors achieved good performance in predicting prognosis. With the urgent needs of multicentric 18F-FDG PET/CT trails, robust and explainable radiomics models have great potential in decision making and prognosis prediction of lung adenocarcinoma.
Water status and macronutrient concentrations, but not carbon status, of Viscum album ssp. album are determined by its hosts: a study across nine mistletoe–host pairs in central Switzerland
Authors: Wang Ao , Bose Arun K. , Lehmann Marco M. , Rigling Andreas , Gessler Arthur , Yu Longfei , Li Maihe 
Published: May 2023

IntroductionEuropean mistletoe,Viscum albumL., is a hemiparasite that can infect various tree species, yet our understanding of its physiological interactions with host species is limited.MethodsNine mistletoe–host pairs (i.e.V. albumssp.albumgrowing on nine different broadleaf tree species) under different growth conditions in central Switzerland were selected to examine the carbon, water and nutrient relationships between mistletoe and its hosts. We measured leaf morphological traits, isotopic compositions (δ13C and δ15N), concentrations of non-structural carbohydrates (NSC) and specific compounds (i.e. mobile sugars and starch), and macronutrients (i.e. N, P, K, Ca, Mg, S) in leaf and xylem tissues of both mistletoe and its hosts.Results and DiscussionThere were only non-significant relationships between NSC concentrations in mistletoe and in its host species across the nine mistletoe–host pairs, suggesting the carbon condition ofV. albumssp.albumis determined by both the heterotrophic carbon transfer and self-photosynthetic capacity among different mistletoe-host pairs. However, mistletoe leaf morphological traits (single leaf area and mass, and leaf mass per unit leaf area) did not change across the nine mistletoe–host pairs, and mistletoe leaf δ13C, water content and macronutrient concentrations were linearly correlated with those in the host leaves. Macronutrients showed accumulations in mistletoe across the nine pairs. Further, tissue N concentrations were significantly higher in mistletoe grown on N-fixing hosts than on non-N-fixing hosts. Finally, leaf N:P in mistletoe was significantly correlated with the ratio in the host across the nine mistletoe–host pairs. Overall, our results indicate strong relationships between mistletoe and its hosts for water- and nutrient-related traits, but not for carbon-related traits, which demonstrates thatV. albumssp. album can adjust its physiology to survive on different deciduous tree species hosts and under different site conditions.
Annual compost amendments can replace synthetic fertilizer, improve soil moisture, and ensure tree performance during peach orchard establishment in a humid subtropical climate
Authors: Lawrence Brian T. , Melgar Juan Carlos 
Published: May 2023

The application of organic matter (OM) to peach orchards is currently uncommon in commercial operations but could potentially replace synthetic fertilizers and improve long-term orchard sustainability. The purpose of the study was to monitor how annual applications of compost to replace synthetic fertilizer would change soil quality, peach tree nutrient and water status, and tree performance during the first four years of orchard establishment within a subtropical climate. Food waste compost was incorporated before planting and added annually over four years with the following treatments: 1) 1x rate, applied as dry weight at 22,417 kg ha-1 (10 tons acre-1) incorporated during the first year and 11,208 kg ha-1 (5 tons acre-1) applied topically each year after; 2) 2x rate, applied as dry weight at 44,834 kg ha-1 (20 tons acre-1) incorporated during the first year and 22,417 kg ha-1 (10 tons acre-1) applied topically each year after; and 3) control, with no compost added. Treatments were applied to a virgin orchard location, where peach trees had never previously been grown, and to a replant location, where peach trees had been grown previously for more than 20 years. Synthetic fertilizer was reduced in the 1x and 2x rates by 80 and 100% during the spring and all treatments received the summer application according to standard practice. Soil OM, phosphorus and sodium all increased with the addition of 2x compost in the replant location at 15 cm depth, but not within the virgin location compared to the control treatment. The 2x rate of compost improved soil moisture during the growing season, but tree water status was similar between treatments. Tree growth was similar between treatments in the replant location, but the 2x treatment had larger trees compared to the control by the third year. Foliar nutrients were similar between treatments over the four years, while 2x compost rate increased fruit yield in the virgin location compared to the control the second year of harvest. The 2x food waste compost rate could be considered as a replacement for synthetic fertilizers and to potentially increase tree growth during orchard establishment.
Application of ISAK 35 concerning the Presentation of Financial Statements of Non-Profit Oriented Entities (Case Study at the Al - Marhamah Orphanage Medan)
Authors: Ansari Jevri , Harmain Hendra , Nurwani Nurwani 
Published: May 2023

This study aims to apply the concept of ISAK 35 concerning the Presentation of Financial Statements of Non-Profit Oriented Entities at the Al – Marhamah Orphanage in Medan. The concept of ISAK 35 is to allow non-profit-oriented entities to adjust the descriptions used for some of the posts contained in the financial statements and the financial statements themselves include statements of financial position, comprehensive income statements, reports of changes in net assets, statements of cash flows, and notes to financial statements. At the Al-Marhamah Orphanage in Medan, it has not yet implemented or made financial statements in accordance with this concept, so researchers apply the financial statements. The purpose of this study is to find out how the presentation of financial statements at the Al - Marhamah Medan Orphanage in accordance with the concept of ISAK 35 and to find out the benefits of financial statements that have used ISAK 35 for the Al - Marhamah Medan Orphanage. The data types used are primary data and secondary data. Data collection techniques are carried out using interview and documentation techniques. The data analysis method used is descriptive qualitative. The results of this study are the form of financial statements at the Al - Marhamah Medan Orphanage in 2020 has been adjusted to the concept of ISAK 35, which consists of a Comprehensive Income Report, Cash Flow Statement, Net Asset Change Report, Financial Position Report and Notes to Financial Statements, improving the quality of their financial statements, which later serves as an easier for aid providers to read how the financial statements are and to complete the elements Financial statements and making it easier to find out the surplus (deficit) of orphanage assets in the current year, besides being important, are also very helpful for the following years
EKSPLORASI ETNOMATEMATIKA PADA TARI NAPA DI MASYARAKAT BENGKULU SELATAN
Authors: Syaipul Amri  , Mella Dwi Santia  
Published: May 2023

Penelitian ini bertujuan untuk mengetahui aktivitas etnomatematika Tari Napa pada masyarakat di Bengkulu Selatan dan mengetahui konsep matematika yang diaplikasikan. Jenis penelitian ini adalah kualitatif deskriptif. Teknik pengumpulan data yang dilakukan adalah observasi, wawancara dan dokumentasi. Hasil penelitian menunjukan bahwa, aktivitas etnomatematika Tari Napa mengandung aspek matematis pada alat-alat yang digunakan dan gerakan. Aspek matematis tersebut meliputi menghitung (jumlah penari dan jumlah alat musik yang digunakan), menentukan lokasi (penentuan posisi penari, posisi alat musik, dan lokasi penyimpanan aset yang digunakan), mengukur (mengukur jarak antar penari), mendesain (pakaian yang digunakan penari seperti celana panjang, baju kemeja, peci, dan kain), bermain (menentukan aturan gerakan Tari Napa dan cara memainkan alat musik) dan menjelaskan (menjelaskan makna dari gerakan Tari Napa). Konsep matematika yang diaplikasikan meliputi jenis- jenis sudut, yaitu sudut siku-siku pada gerakan tangan penari saat melakukan gerak menangkis, sudut lancip pada gerakan tangan penari saat melakukan gerak memukul, dan sudut tumpul pada gerakan tangan penari saat melakukan gerak silek atau menghindar secara berhadapan, dan beberapa bangun datar seperti, persegi panjang yang terdapat pada alat Tari Napa yaitu tikar, serta lingkaran yang dapat ditemukan pada gendang atau rebana sebagai alat yang digunakan pada saat Tari Napa.
Kata Kunci : Tari Napa Bengkulu Selatan, Etnomatematika
Assessment of Skeletal and Dental Pattern of the Mandible of Class II Division 1 Malocclusion: Comparative Cephalometric Study
Authors: Al-Azzawi Arkan Muslim , Sahib Wisam Wahab , Al-Khafaji Thaer Jaber 
Published: May 2023

Background: Class II division 1 malocclusion represents the most common skeletal discrepancy which orthodontists see in daily practice. The understanding the morphology of the mandible is a key element in diagnosis and treatment planning in the field of orthodontics and orthognathic surgery. This study provides new information about the skeletal and dental pattern of the mandible with class II division1, based on skeletal II for Iraqi adult sample aged (18 - 26) yearsin comparison with normal occlusion by means of cephalometric measurements used by clinical practitioners. (20) males and (21) females with a skeletal Class II were chosen and compared with (26) males and (28) females with normal occlusion by using the (ANB) angle. Nine angular measurements and eight linear measurements have been used in this study.
Results: the results were as follows: When the angular and linear measurements of skeletal class I and II overall, males and females samples were compared, the retrusion of mandible with a short length of the ramus and a tendency of a backward rotation of the mandible in relation to the cranial base in skeletal class II are the most important causes of class II malocclusion with the facial profile is more convex in skeletal class II overall and males samples while, all the angular and linear measurements used in this study show no significant difference betweenskeletal class I and II females, except the facial profile is more convex in skeletal class II females sample. The lower incisors is more procline in class II than in class I overall sample but this difference is not statistically significant in males and females sample. No significant difference could be noted between sexes of skeletal class II in the angular measurements. Most linear measurements were larger in males than in females class II division 1 except for twomeasurements the posterior cranial base length and the length of the body of the mandible show no significant difference between class II division 1 males and females.
Pengaruh Variasi Kedalaman Parit dan Frekuensi Penyiraman Pada Pertumbuhan dan Hasil Tiga Varietas Bawang Merah
Authors: Nur Subandi 
Published: May 2023

Penelitian ini bertujuan mengidentifikasi lengas tanah/kadar air pada perlakuan variasi dalamnya parit dan frekuensi penyiraman, mendapatkan varietas bawang merah yang menghasilkan pertumbuhan dan hasil paling tinggi pada perlakuan variasi dalamnya parit, mendapatkan varietas bawang merah yang menghasilkan pertumbuhan dan hasil paling tinggi pada perlakuan frekuensi penyiraman, mendapatkan varietas bawang merah yang menghasilkan pertumbuhan dan hasil paling tinggi pada perlakuan variasi dalamnya parit dan frekuensi penyiraman, mengetahui adanya interaksi antara varietas bawang merah, variasi dalamnya parit dan frekuensi penyiraman yang diujikan dilihat dari variabel pertumbuhan dan hasil bawang merah. Penelitian dilakukan di Desa Pulosari Kecamatan Brebes Kabupaten Brebes selama tiga bulan (Juni sampai dengan Agustus 2019). Penelitianan dilakukan dengan menggunakan Rancangan Petak Petak Terbagi (Split Split Plot Dsign) dengan rancangan dasar RAKL dan diulang 3 (tiga) kali. Faktor yang dicoba adalah : Kedalaman Parit (P = 3), Varietas (V = 3) dan Frekuensi Penyiraman (F = 2). Data yang diperoleh dianalisa dengan menggunakan analisis sidik ragam pada taraf kesalahan 5 %, apabila terjadi perbedaan nyata dilanjutkan dengan Uji Beda Nyata Terkecil (BNT) taraf 5 %. Hasil penelitian menunjukkan bahwa Kadar lengas tanah tertinggi pada perlakuan kedalaman parit dan frekuensi penyiraman dimiliki oleh perlakuan kedalaman parit 70 cm dan frekuensi penyiraman dua kali sehari (37,06 mm.10 cm-1), varietas bawang merah yang menghasilkan pertumbuhan dan hasil paling tinggi pada perlakuan variasi kedalaman parit dan frekuensi penyiraman adalah Sumenep (V3) dan adanya interaksi varietas, kedalaman parit dan frekuensi penyiraman terhadap pertumbuhan dan hasil bawang merah.
Design and Analysis for Heat Transfer Through Twisted Tape with Nanoparticles
Authors: Subravel  V  , Chandrasekar V  
Published: May 2023

Different techniques have been used to achieve a high heat transfer rate. Among them, one of the advanced techniques is a suspension of nanoparticles in the base fluids as water and coated with aluminum and titanium. The present work has been carried out on a double pipe heat exchanger with twisted tape insert with twist ratio (y/w = 4 and 6) and thickness (0.8mm) for heat transfer investigation of water to water and nanofluid to water with counter flow arrangement under turbulent flow conditions. The computational fluid dynamic code simulates different concentrations of nanofluid (0.01% to 0.19%) in ANSYS FLUENT R 18.1 software. The overall heat transfer coefficients for all concentrations are measured as a function of the hot and cold stream's mass flow rates. The thermal performance parameter overall heat transfer coefficient is compared for nanofluids with water. The work concludes that there is a good enhancement in heat transfer rate using nanofluid.
La Realidad Virtual como estrategia para la Enseñanza de las Ciencias Sociales
Authors: Borja Solano Marco Paulino 
Published: May 2023

La evolución de la tecnología en la sociedad ha dando como resultado un cambio en la formación de futuros profesionales. Sin embargo, la educación no queda fuera de esta transición, y se ha visto obligada a buscar nuevas alternativas que vayan acorde a las necesidades actuales. Los docentes se adaptan a una metodología tradicional y esto se evidencia en el proceso de aprendizaje; las alternativas e implementación de nuevas estrategias quedan relegadas y no se aplican ideas innovadoras. Por este motivo, el presente trabajo de investigación tiene como finalidad plantear a la realidad virtual como estrategia metodológica para la enseñanza de las ciencias sociales dirigida a estudiantes de educación superior. Se utilizó un enfoque cuantitativo y un método descriptivo, dando como resultado una gran aceptación de la realidad virtual como estrategia metodológica para la enseñanza de las ciencias sociales por parte de los estudiantes de Institutos de educación superior. Se concluye que se debe impartir nuevas metodologías que ayuden a la formación docente en su etapa de pregrado dejando así estrategias metodológicas tradicionales que impiden el desarrollo innovador de la educación.
La tala de árboles: Una Afectación Ambiental, consecuencia de la disminución del Caudal del Rio Carraipia, corregimiento del Municipio de Maicao
Authors: Roldan Caziz Reyes María , Zambrano Palomino Mariela , Tovar Rúa Diana Cecilia 
Published: May 2023

El presente artículo, busca reflexionar sobre la tala de árboles: una afectación ambiental, consecuencia de la disminución del caudal del río Carraipia, corregimiento del municipio de Maicao, recopila información relevante con respecto al medio ambiente, habitad, biodiversidad teniendo como objetivo, analizar la tala de árboles como afectación ambiental, diagnosticando los daños, la desolación o perjuicios en el contexto natural que provoca el hombre, proponiendo prácticas de cuidado, para así velar por el área cercana del rio. Por tal motivo se realizó una revisión literaria sin hacer a un lado la perspectiva interpretativa, con enfoque cualitativo, y el uso del método descriptivo en contexto teórico documental, tomando la revisión bibliográfica de trabajos de investigación, artículos científicos y tesis entre otros: Ayala N. y Ramírez N. (2021), Barriga (2019), Montoya M. (2021), Blanco (2017). Para la recopilación de datos se utilizó técnicas de entrevista a los habitantes aledaños a la cuenca del rio Carraipia. A un nivel social, se hace de gran importancia esta investigación ya que permitirá crear conciencia en cada uno de los habitantes del corregimiento de Carraipia, apuntando desde la academia, a un impacto en el mejoramiento de las condiciones ambientales. En este sentido, los hallazgos finales de la investigación se encaminaron a conocer la importancia que tiene el caudal del río sobre la supervivencia de la población.
Análisis Doctrinario de la Tenencia Compartida en el Ecuador: Criterios y Factores de Valoración
Authors: Pico Acosta Adrian Bolivar 
Published: May 2023

El Ecuador reconoce la figura jurídica de la tenencia de menores, establecida y regulada en el Código Orgánico de la Niñez y Adolescencia, la doctrina ha establecido que esta es una responsabilidad y obligación compartida entre sus progenitores tanto en varios aspectos. Sin embargo, surgen situaciones de vulnerabilidad de los menores como la alienación parental, ante ello, es importante que el poder judicial logre enfocar sus actuaciones al momento de administrar justicia en la búsqueda del bienestar del menor, adjudicando la tenencia en pro de las mejores condiciones para el mismo.
La principal problemática es la ejecución de la normativa al momento de existir la disolución del vínculo conyugal, dejando al menor en una situación de vulnerabilidad para la determinación de su tenencia por uno de sus progenitores; siendo importante que el juzgador evidencie y valore todos los elementos que conllevan a que los niños o adolescentes se encuentre en un lugar de libre desarrollo emocional, económico, etc.
La metodología utilizada en este ensayo es de carácter cualitativa, con enfoque critico-jurídico que tiene soporte en el método analítico bibliográfico y analítico sintético, de tipo descriptivo de la normativa jurídica actual sobre la tenencia de menores y de la resolución judicial de la Corte Constitucional frente a la derogación de la preferencia materna en pro de una búsqueda de igualdad y sobre todo del ejercicio y corresponsabilidad de la tenencia compartida dejando de lado los roles de género y permitiendo al menor vivir en un ambiente sano y libre de violencia.
Estrategias de retención del talento en un Contexto Internacional
Authors: Huaraca-Carhuaricra Carlos Guzmán , De la Cruz-Salazar Margoth Jessica , Valdez-Duran James , Li-Parra Lorena , Melgarejo-Cabello Natalia Mabel 
Published: May 2023

El talento es el activo más relevante, valioso y efectivo de una organización, y retenerlos es una de las tareas más titánica para la alta gerencia, porque los costos de reemplazo significativos están asociados con una alta rotación, se debe desarrollar una política integral de retención de talentos (RT) para abordar este tema central. Este artículo de revisión está centrado en la identificación de estrategias de retención del talento (ERT) relacionados como prácticas gerenciales dentro de la organización, el objeto de estudio es analizar las investigaciones realizadas en la web o en revistas, Scopus, Proquest, Scielo, y Science, a nivel internacional, entre los años 2018 al 2023, para llevar a cabo este estudio se realizó revisión bibliográfica descriptiva mediante métodos cualitativos, teniendo en cuenta 72 artículos de diferente publicación en contenido, época y continente, destacando los resultados obtenidos a otras industrias privadas con mayor número de revistas que evidenció que la gestión estratégica del talento GET (Oportunidades de desarrollo, compensación, ambiente de trabajo, marca de empleador, confianza organizacional, crecimiento profesional, apoyo y reconocimiento laboral, equilibrio vida-trabajo, evaluaciones de desempeño, satisfacción laboral, compromiso) son relevantes para la ERT.