bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified subtotal laryngectomy with formation of a tracheopharyngeal shunt for locally advanced cancer of the larynx and hypopharynx
Authors: Malysheva E. N. , Kulbakin D. E. , Choynzonov E. L. , Krasavina E. A. 
Published: August 2023

Aim. To study the effectiveness of modified subtotal laryngectomy with the formation of a tracheopharyngeal shunt in patients with locally advanced cancer of the larynx and laryngopharynx.Materials and methods. We conducted a cohort study on the use of combined treatment (surgical and radiation/ polychemotherapy) in 25 patients: 24 men, 1 woman; median age – 56 years. The subtotal laryngectomy technique that we developed and used included the preservation of one arytenoid cartilage, the posterior third of the vocal fold, and the recurrent nerve on the side not affected by the tumor. We studied postoperative complications, the length and diameter of the tracheopharyngeal shunt, the functioning of the arytenoid cartilage, the frequency of voice recovery and its quality, and overall and relapse-free survival.Results. In the postoperative period, 8 (32%) patients developed a pharyngocutaneous fistula; tracheal stenosis after tracheostomy was observed in 8 (32%) cases. The length of the tracheopharyngeal shunt varied from 16.4 to 25.6 mm, in all cases its course was tortuous, the diameter of the preserved part of the vocal fold varied from 1.1 to 1.5 mm. 24 (96%) patients demonstrated the functioning of the arytenoid cartilage and its work as a valve. Voice function recovered in 24 (96%) patients. Fundamental frequency was 155.3 ± 20.9 Hz, maximum phonation time of the vowel “A” – 3.5 ± 1.0 s, duration of pauses in phrase – 0.24 ± 0.03 s, speech rate – 99.8 ± 8.4 words/ min, number of words in phrase 6.5 ± 0.3. The average value of the Acoustic Voice Quality Index was 6.74, which indicates dysphonia (for the Russian language, the threshold value for dysphonia is 4.86), but this did not interfere with patients’ communication at home and on the phone. Overall and relapse-free survival at 1, 2, and 3 years were 100%, 89%, 78% and 86%, 78%, 72%, respectively.Conclusion. The method of operation proposed by us contributes to the restoration of voice function in the majority of patients with oncological outcomes comparable to total laryngectomy.
Incidence and Antibiogram of Uropathogens Isolated from Pregnant Women Attending Antenatal Clinic in a Public Hospitalin Yola, Adamawa State, Nigeria
Authors: Sale, M.  , Kwaji M.  , Wakawa, H. Y.  
Published: August 2023

Urinary tract infection during pregnancy including asymptomatic bacteriuria has been associated with some adverse outcomes for the mother and foetus. Studies have shown that pregnant women with urinary tract infections have a significantly higher rate of intra-uterine growth restriction, pre-eclampsia, caesarean and pre-term deliveries. This study was undertaken to determine the occurrence, distribution and antibacterial susceptibility pattern of uropathogens among pregnant women attending antenatal clinic in a public hospital in Yola. A total of 200 clean catch mid-stream urine samples were collected from pregnant women and inoculated on cysteine lactose electrolyte deficient agar for bacterial count and isolation of uropathogens. The isolates were also screened for ability to form biofilms using Congo Red Agar method and antibiotic susceptibility test was done on the isolates using agar disk diffusion method. The incidence of UTI among the pregnant women was found to be 90%. The predominant uropathogens were E. coli (46.0%), S. aureus (20.0%) and Klebsiella pneumoniae (17.0%) while the least occurring uropathogen was Proteus sp. (2.0%). Women in the third and first trimester of pregnancy had the highest occurrence of UTI. A total of 47.0% of the isolates produced biofilm in vitro with the highest biofilm production observed among Proteus sp. (75.0%) and Pseudomonas aeruginosa (60.0%) isolates. The occurrence of antibiotic resistance among the isolates was high, with greater susceptibility observed to quinolone and third generation cephalosporin. The E. coli isolates demonstrated varying levels of resistance to all the antibiotics tested. Because of the gravity of problems of UTI in pregnancy and that 9 in 10 pregnant women from this study have symptomatic or asymptomatic infection, it is concluded that pregnant women should be screened for urinary tract infection during antenatal visits especially during the first and third trimesters of pregnancy.
Pendampingan Usaha Home Industry Gula Merah Tebu Melalui Atribut Produk di Desa Latellang
Authors: Hazrina  , Harmilawati  
Published: August 2023

Abstrak
Kegiatan pengabdian masyarakat ini membahas tentang pendampingan usaha home industry gula merah tebu melalui atribut produk di Desa Latellang Kec. Patimpeng Kab. Bone. Pengabdian ini melakukan salah satu upaya untuk meningkatkan usaha home industry memalui atribut dan mempromosikan melalui media sosial. Tanaman tebu sangat potensial untuk terus dikembangkan untuk menghasilkan berbagai produk-produk lainnya untuk memenuhi kebutuhan masyarakat. Selain gula pasir, dari tanaman tebu masih terdapat sejumlah produk agroindustri lain yang masih terbuka untuk dikembangkan, salah satunya adalah gula merah tebu. gula merah tebu akan memacu kegiatan ekonomi di pedesaan baik ke arah hulu berupa kegiatan penyediaan bahan baku dan kebutuhan produksi lainnya maupun ke hilir berupa kegiatan pemasaran dan produksi produk produk agroindustri lainnya.

Kata Kunci : gula merah, tebu, agroindustry, home industri

Abstract
This community service activity discusses assisting the brown sugar cane home industry business through product attributes in Latelangg Village, Kec. Patimpeng Regency. bones. This service makes one of the efforts to improve home industry businesses through attributes and promoting through social media. Sugarcane plants have the potential to continue to be developed to produce various other products to meet the needs of the community. Apart from granulated sugar, from the sugarcane plant there are still a number of other agro-industrial products that are still open for development, one of which is cane brown sugar. Cane brown sugar will spur economic activity in the countryside both upstream in the form of activities providing raw materials and other production needs as well as downstream in the form of marketing activities and the production of other agro-industrial products.

Keywords: brown sugar of the sugar cane,agroindustry,home industry
Pelatihan Penggunaan Media Pembelajaran Berbasis Aplikasi Canva Education di SD 256 Malimongeng
Authors: Hasan Nurfadhilah , Mudjrimin Jusri 
Published: August 2023

Pengabdian didasarkan pada kemajuan zaman yang dilihat dari berkembangnya teknologi dan komunikasi, sehingga peneliti bermaksud memberikan pelatihan pada guru dalam menggunakan alat teknologi. Sehingga pembelajaran dapat disampaikan dengan mudah, kreatif, dan inovatif kepada peserta didik yang tentu saja dapat menarik minat dan meningkatkan prestasi belajar. Berdasar pada hasil observasi di lokasi ditemukan bahwa guru memiliki antusias pada penggunaan media berbasis teknologi, namun hasil wawancara dari beberapa guru diperoleh informasi bahwa, mereka belum pernah mendapatkan wadah yang memfasilitasi dalam proyek pelatihan penggunaan media pembelajaran berbasis aplikasi canva education. Oleh karena itu, peneliti termotivasi untuk melakukan penelitian berjudul “Pelatihan Penggunaan Media Pembelajaran Berbasis Aplikasi Canva Education di SD 256 Malimongeng”. Kegiatan ini diharapkan dapat memberikan input yang bermanfaat. Metode yang dilaksanakan pada pelatihan ini yaitu sosialisai dan pengenalan aplikasi. Beberapa pokok pembahasan yang disampaikan yakni pengenalan aplikasi Canva, fitur- fitur template, kelebihan dan kekurangan, dan tahap-tahap pembuatan proyek media pembelajaran. Hasil yang didapatkan setelah pelatihan dilaksanakan yaitu, pemahaman dan kemampuan guru dalam menggunakan teknologi meningkat terkhusus guru di SD 256 Malimongeng pada penggunaan media pembelajaran berbasis aplikasi Canva Education. Pelatihan ini diharapkan mampu mengasah kompetensi guru dalam menggunakan media pembelajaran berbasis digital, dan menerapkan prose belajar mengajar yang bermakna, inovatif, dan solutif.
ANÁLISE DOS ÓBITOS EVITÁVEIS EM CRIANÇAS ANTES E DURANTE A PANDEMIA DE COVID-19: ESTUDO TRANSVERSAL
Authors: Pereira Carrilho Mariana , Oliveira Karasek Hazime Desirée , Angelin Maria Fernanda , Pereira Ingrid Adriana , Toshio Enohi Ricardo , Conceição Martins Lourdes 
Published: August 2023

Introdução: Óbitos infantis por causas evitáveis são aqueles preveníveis por ações diretas ou indiretas dos serviços de saúde. Taxas elevadas deste tipo de mortalidade denotam um sinal de alerta, pois indicam que a atenção integral à saúde prestada pode estar deficiente e que sua qualidade precisa ser melhorada. Objetivo: Análise dos óbitos evitáveis em crianças antes e durante a pandemia da COVID19. Métodos: Estudo transversal com utilização de dados secundários obtidos junto ao banco de dados do Sistema Único de Saúde (DATASUS) para o período de 2018 a 2021. As informações de óbito evitáveis de crianças de zero a quatro anos de idade foram obtidas do DATASUS. Foi realizada a análise descritiva. O nível de significância foi de 5%. Resultados: O período pré- pandemia apresentou maior percentual de óbitos infantis (55,3%), sendo o gênero masculino o mais afetado (54,3%), na raça/cor da pele branca (66,0%), residentes em municípios do estado de São Paulo (95,1%), filhos de mães com escolaridade entre 8 e 11 anos de estudo (53,5%), de gestação única (80,8%), parto cesária (50,7%), com assistência médica (61,6%). Os óbitos infantis por causas evitáveis tiveram uma alta prevalência no período de pré-pandemia (12.735). Entre os municípios da Baixada Santista, Guarujá se destacou pelo maior número de óbitos (68). Conclusão: Para que haja uma adequada vigilância de óbitos infantis, especialmente no que diz respeito as causas evitáveis, se faz necessário a realização periódica de pesquisas semelhantes a esta.
Machine learning and IoT-based garbage detection system for smart cities
Authors: Sharma Raj Kumar , Jailia Manisha 
Published: August 2023

Today, detecting waste, collecting it, processing it, and getting rid of it are among the most significant environmental issues in developing and undeveloped counties. It has been observed that a large amount of garbage remains strewn on the roadside. This study presented a garbage detection technology such as machine learning and gadgets connected to the Internet of Things (IoT), such as an IP-enabled CCTV camera, to take pictures and send them to the city’s main server. The input images are transformed into a two-dimension array of integers using Python modules and divided into the garbage and no garbage classes. There is an 80:20 split between the training and testing datasets from the input dataset. Preprocessed images are then utilised as inputs for a wide range of machine learning and neural network models for classification; these include K-Nearest Neighbour (KNN), Logistic Regression (LR), Naive Bayes (NB), and Support Vector Machine (SVM). The test data sets are applied, and a confusion matrix is formed for all models to analyse the efficiency and performance of the trained models. Results from the confusion matrix are contrasted with those from the area under the Receiver characteristics operating curve (AUC). As a result, the ConvNet model is best suited for classifying garbage or no garbage present in open space, and the LR model proposed best suits the garbage detection problem. The proposed models are best suitable for improving the efficiency of existing garbage identification systems and developing a new system for smart cities.
Pengaruh Penambahan Em4 Pada Limbah Cair Tahu Terhadap Biogas
Authors: ANGGRAENI ANI , Mulyadi  
Published: August 2023

Tofu is a type of food that is familiar to Indonesian people. From the processing process it has waste. In general, tofu solid waste can be used for animal feed. Meanwhile, tofu waste in liquid form is discharged into the waters resulting in a negative impact on water quality resulting in a foul odor in the river from the tofu liquid waste. Liquid tofu waste can actually be used as biogas energy, but it is very rare because it requires a lot of money.
The sole independent male tofu factory located in Kp Salakopi RT 02 / RW 12, Des. Haur Wangi, West Java, which already has a biogester tube from a government program so that tofu liquid waste can be used as biogas, but the biogas produced is not optimal.
Therefore the researchers conducted research by adding EM4 biogester to tofu liquid waste as much as 0.2% in a holding pond of 6X3X0.1 = 1.8 X 1000 = 1800 Liters of tofu liquid waste from 10 December 2022 to 21 January 2023. From the results of the reset, the results of the initial test results showed that the average pressure produced was only 0.8 Bar and the average pressure generated after the addition of EM4 bioactives became 1.5 Bar. The characteristics of the premix fire produced by tofu liquid waste biogas is blue, smells bad , and not smoky.
Environmental Kuznets Curve Approach to Estimate Ecological Footprint in Pakistan
Authors: Yamin Rukhsar , Hanif Uzma , Anwar Muhammad Awais , Arshed Noman 
Published: August 2023

The aim of the study is to explore the various variables that lead to Pakistan's environmental deterioration. The impact of macroeconomic factors of environmental deterioration is investigated to fulfill the objective of the study. The impact of determinants on environmental degradation from 1990 to 2020 was explored in this study. The dependent variable is Ecological Footprint, which is used as a proxy for environmental deterioration, whereas the independent variables are Trade openness, Urbanization, foreign direct investment, and per capita income growth. However, square of per capita also included in a model to verify the phenomena of Kuznets curve. The variable's stationarity was checked and used the unit root test (ADF and PP), which indicated that it exists at the first difference. According to the result of stationary ARDL cointegration model is applied. The result of the test showed the long run relation among the variable. The coefficient of GDP is positive and squared GDP is negative, this means that if there is a consistent rise in GDP, then the negative effect of squared GDP will overcome the positive effect of level GDP. Beyond this point increase in GDP will reduce the ecological footprint. This phenomenon was discussed earlier as the environmental Kuznets curve.
Reading Magical Realism in Salman Rushdie’s Midnight’s Children for Supporting EFL Students’ Cross-Cultural Awareness
Authors: Ajeng Galuh Dwi , Maximilian Aksendro 
Published: August 2023

The present study explores the magical realism contents in the Midnight’s Children by Salman Rushdie. It also aims to investigate the way the magical realism contents to be adapted and integrated into the cross-cultural understanding material to support the EFL students’ cross-cultural awareness. The qualitative research method is employed for analysing the primary source by consulting it to the secondary sources. From the story, it is found that the struggle is available between two opposing structures in a mystical realist document, and one of them is working toward the development of a fantasy universe from the other. These are the worlds of fantasy and life, and they are all present and vying for the reader's interest. Thus, the study may deduce that Rushdie employs magical realist features such as time dilation and the introduction of myth, legends, and folklore. Rushdie has built something unique with Midnight’s Children, and Saleem is honestly attempting to tell the tale of his existence, and the life of the new country. Moreover, based on the contents found, the instructional activities can be designed by adapting the magic realism content found in the story to build the cross-cultural awareness of the Indonesian EFL students. Moreover, magic realism content can also be an alternative and variation on the language and cultural classes.
Modern non-invasive diagnosis of endometriosis
Authors: Kudryavtseva E. V. , Geets A. V. , Mangileva Ya. A. , Chizhova A. V. , Patsyuk O. V. 
Published: August 2023

Introduction. Endometriosis is a disease characterized by an overgrowth of morphologically and functionally endometrium-like tissue outside the uterine cavity. Early diagnosis of endometriosis is very difficult. The gold standard for diagnosis is the surgical method − laparoscopy, performed for infertility, pelvic pain or the presence of pelvic masses. However, this approach is currently being reconsidered, and the search for endometriosis markers for earlier diagnosis of this disease is relevant.The purpose of the literature review was to summarize the current data on promising noninvasive markers of endometriosis determined in various biological media.Materials and methods. Scientific literature was searched in PubMed, ResearchGate, and Elibrary databases for 2017−2022 using a combination of Russian and English keywords: endometriosis, endometrioma, endometriosis pathogenesis, peritoneal fluid, biomarkers, serum markers.Results. We evaluated more than 30 putative biomarkers in peritoneal fluid, serum, urine, and saliva, as well as their combinations in publications that met the selection criteria. Studies have evaluated the diagnostic value and efficacy of endometriosis biomarkers, but the results of these studies have sometimes been inconsistent. We were unable to identify a single biomarker or combination of biomarkers that was unequivocally clinically useful. The most significant changes in biochemical composition were observed in peritoneal fluid, but it requires invasive intervention to obtain it.Discussion. Saliva and urine studies have shown promising results in terms of diagnostic accuracy, but the evidence was of low quality for introduction into clinical guidelines. A number of serum biomarkers may be useful either for detecting endometriosis at early stages or for differentiating ovarian endometrioma from other benign ovarian masses, but the evidence for meaningful conclusions is insufficient. Conclusion None of the biomarkers have shown sufficient accuracy for clinical use outside of the research environment, yet research in this area remains promising.
Analysis of the toxic effects of fluoroquinolones in laboratory rabbit models
Authors: Izmozherova N. V. , Bazarnyi V. V. , Bakhtin V. M. , Polushina L. G. , Maksimova A. Yu. 
Published: August 2023

Introduction. Fluoroquinolones are antibacterials for which the development of cardiotoxicity, hepatotoxicity, nephrotoxicity and connective tissue damage has been noted. The likely mechanism for the development of these reactions is magnesium metabolism disorder. An available method to detect fluoroquinolones toxicity in animal experiments is a blood biochemical test.The aim of the work was to identify the biochemical signs of the toxic effects of fluoroquinolones in laboratory rabbit models.Materials and methods. Twenty male rabbits randomised into three groups were included in the study: 6 control animals; 7 rabbits treated with ciprofloxacin 150 mg/kg 14 days; 7 rabbits treated with levofloxacin 150 mg/kg 14 days. Serum levels of albumin, alanine aminotransferase (liver damage marker), creatinine (nephrotoxicity marker), creatine kinase MB (cardiotoxicity marker), matrix metalloproteinase 9 (connective tissue damage marker), serum and plasma magnesium content were studied in this work. Data are presented as mean (standard deviation).Results. Serum levels of albumin, alanine aminotransferase and creatinine did not change during the experiment. Rabbits treated with levofloxacin had 2.0–2.5 times lower values of CF creatine kinase activity than control animals. There was double increase of serum concentration of matrix metalloproteinase 9 in ciprofloxacin group in comparison with control (70,17 (20,88) and 38,10 (16,04) ng/ ml, p = 0,019). Magnesium content was unchanged with both fluoroquinolones.Discussion. The absence of signs of hepatotoxicity and nephrotoxicity is consistent with their low frequency of detection in clinical and experimental studies. A decrease in the activity of creatine kinase MB in animals treated with levofloxacin has not been described in the literature. An increase in the concentration of metalloproteinase 9 is evidence of destruction of connective tissue structures. The absence of changes in serum and plasma concentrations of magnesium is explained by the functioning of the systems maintaining the constancy of its content in blood.Conclusion. No biochemical evidence of hepato-, nephro- and cardiotoxic effects of ciprofloxacin and levofloxacin at the doses of 150 mg/kg for 14 days was shown in rabbits; no magnesium metabolism disorders were shown, and the ability of ciprofloxacin to increase the serum content of matrix metalloproteinase type 9 was demonstrated. The proposed model can be used to investigate ways to prevent the toxic effects of fluoroquinolones on connective tissue structures.
Reflexo da pandemia nas internações para tratamento da doença biliar no Brasil nos anos de 2019 e 2020
Authors: Nogueira Paulo Luiz Batista , Nachi Arestides Massao , Saretto Bruno de Oliveira , Costa Filipe Amaral , Andrade Gabriel Silva de , Barbosa João Víctor Manarelli , Souza Júnior Reginaldo José de , Ali Samuel Santos , Rezende Neto Jose Antônio dos S. R. de 
Published: August 2023

As patologias da vesícula biliar são comuns no Brasil e responsáveis por cerca de 60 mil internações por ano pelo Sistema Único de Saúde. A prevalência de colelitíase aumenta em adultos a partir dos 40 anos e é mais prevalente no sexo feminino. Durante a pandemia de COVID-19, estudos mostraram uma redução no número de internações para tratamento cirúrgico. Objetivo: Identificar os fatores epidemiológicos das hospitalizações por doenças que acometem a vesícula e as vias biliares ocorridas no Brasil entre janeiro de 2019 e dezembro de 2020 e o impacto da pandemia nos procedimentos cirúrgicos eletivos. Métodos: Trata-se de um estudo epidemiológico, observacional, analítico de corte transversal utilizando dados do Sistema de Internações Hospitalares nos anos de 2019 e 2020. Foram incluídos pacientes maiores de idade, internação de caráter eletivo e com diagnóstico principal preenchido com códigos CID-10 referente às doenças biliares, com as seguintes variáveis: ano e mês de competência, caráter da internação, idade, diagnóstico principal, dias de permanência, internação em unidade de terapia intensiva, evolução, região de residência, procedimento realizado, raça/cor, sexo e valor total. Resultados e Conclusão: Foram observados um total de 210.411 hospitalizações, com idade média de 47,18 anos, maioria pertencente ao sexo feminino. A maioria teve evolução por alta com custo hospitalar médio igual a R$ 857,73, sendo a principal causa de hospitalização por código de procedimento descrito como colelitíase e predomínio na região Sudeste do Brasil. No ano da pandemia houve redução significativa da proporção de pacientes internados entre março a agosto de 2020 em comparativo a 2019. Palavras-Chave: Doenças da Vesícula Biliar; Colelitíase; Colecistite aguda; COVID-19; Hospitalização.