bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction models of all‐cause mortality among older adults in nursing home setting: A systematic review and meta‐analysis
Authors: Zhang Shengruo , Zhang Kehan , Chen Yan , Wu Chenkai 
Published: June 2023

AbstractBackground and AimsFew studies have meta‐analyzed different prognostic models developed for older adults, especially nursing home residents. We aimed to systematically review and meta‐analyze the performance of all published models that predicted all‐cause mortality among older nursing home residents.MethodsWe systematically searched PubMed and EMBASE from the databases' inception to January 1, 2020 to capture studies developing and/or validating a prognostic/prediction model for all‐cause mortality among nursing home residents. We then carried out both qualitative and quantitative analyses evaluating these models' risks of bias and applicability.ResultsThe systematic search yielded 23,975 articles. We identified 28 indices that predicted the risk of all‐cause mortality from 14 days to 39 months among older adults in nursing homes. The most used predictors were age, sex, body weight, swallowing problem, congestive heart failure, shortness of breath, body mass index, and activities of daily living. Of the 28 indices, 8 (29%) and 3 (11%) were internally and externally validated, respectively. None of the indices was validated in more than one cohort. Of the 28 indices, 22 (79%) reported the C‐statistic, while only 6 (6%) reported the 95% confidence interval for the C statistic in the development cohorts. In the validation cohorts, 11 (39%) reported the C‐statistic and 8 (29%) reported the 95% confidence interval. The meta‐analyzed C statistic for all indices is 0.733 (95% prediction interval: 0.669−0.797). All studies/indices had high risks of bias and high concern for applicability according to PROBAST.ConclusionWe identified 28 indices for predicting all‐cause mortality among older nursing home residents. The overall quality of evidence was low due to a high degree of bias and poor reporting of model performance statistics. Before any prediction model could be recommended in routine care, future research is needed to rigorously validate existing prediction models and evaluate their applicability and develop new prediction models.
Ex vivo fluorescence imaging for the identification of rhodamine‐labeled bovine serum albumin and chitosan‐coated gold and silver nanoparticles
Authors: Devanabanda Mallaiah , Sana Siva Sankar , Vadde Ramakrishna , Madduri Ramanadham , Venkatesan Raja , Eldesoky Gaber E. , Kim Seong‐Cheol 
Published: June 2023

AbstractTherapeutic potential and toxic effects of in vivo administered gold nanoparticles (GNPs) and silver nanoparticles (SNP) depend on distribution in tissues. Rhodamine (Rho) labeled bovine serum albumin (BSA) and chitosan (Chi) were prepared by covalent conjugation and were characterized by fluorescence spectral analysis. GNP and SNP were coated with the labeled conjugates of BSA and chitosan by adsorption. The soluble Rho‐BSA or Rho‐Chi conjugates, uncoated, and conjugate‐coated GNP, and SNP were orally administered into 8‐week‐old rats. After 24 h, rats were euthanized and the liver, kidney, spleen, and thymus were dissected. The tissues were examined ex vivo using a small animal in vivo imaging system. The liver, kidney, and thymus displayed higher fluorescence due to increased accumulation of Rho‐BSA or Rho‐Chi conjugate‐coated nanoparticles (NPs) in the tissues as compared to the spleen where lower fluorescence was noticed. Tissues obtained from rats that were administered Rho‐BSA or Rho‐Chi conjugate‐coated GNP and SNP showed tenfold higher fluorescence intensity as compared to tissues from rats that were given soluble conjugates or NP alone. The results strongly suggest significant tissue distribution of NP following oral administration.
可動式気管カニューレ「アジャストフィット」の有用性と有害事象の検討(Efficacy and safety of adjustable tracheal cannula “Adjust Fit”)
Authors: 大輔 山田 , 宏隆 澤野 , 知香子 赤井 , 英治 山口 , 淳一郎 加藤 , 将啓 福田 , 裕介 伊藤 
Published: June 2023

要旨気管切開後の気管カニューレの選定は極めて重要である。不適切なカニューレの選択は，チューブの脱離や内腔閉塞などの致死的合併症につながりうる。アジャストフィット® （AF）は，いかなる気管切開孔にも適合することを目指して開発された気管カニューレであり，①ウイングを調節することで気管内に挿入するチューブの長さを調節できる，②シリコン製のスパイラルチューブが柔軟に変形し内腔を保つ，という特徴を持つ。しかし，複数の症例を対象に有用性を検討した研究は少なく，適応や合併症についても未だ不明な点が多い。2017～2022年に当院にてAFが使用された13症例について，その有用性と有害事象を後方視的に検討した。導入理由は，気管前面の皮下組織の肥厚：9例，気管の変形・偏位：3例，気管内狭窄：1例，不明：1例であった（1例重複）。有害事象はカニューレの脱離：4例，内腔狭窄：2例，チューブ先端と気管壁の干渉による換気不全：1例であった。高度の肥満症例や，喉頭全摘出後などの気管の偏移を伴う症例において，AFが有用であり，適応の判断については頸部CT検査が有用であった。しかし，AF特有の構造に起因した，チューブの脱離や内腔の狭窄といった重大な合併症も見られた。AFは適応を慎重に検討し，製品の構造上の特徴を理解して管理を行えば，気道管理において有用なデバイスであると考える。
熱中症治療経過中に悪性症候群との鑑別を要した悪性緊張病の1例(A case of malignant catatonia differentiated from other malignant syndromes during heatstroke treatment)
Authors: 淳 永井 , 憲一郎 西 , 菜都美 山本 , 崇 小松崎 , 明久 岡本 , 夕美 大村 , 大介 水 
Published: June 2023

要旨悪性緊張病は統合失調症のみならず，熱中症などの外的要因を含む様々な病態から移行する致死的疾患であるが，意識障害・発熱・CPK上昇など同様の症状を呈する悪性症候群との鑑別が困難である。今回我々は，病歴不明の状態で救急搬送され，横紋筋融解症を合併した重症熱中症のため集中治療管理を要した症例において，抜管後に再度意識障害・発熱・CPK上昇を認め，救急・集中治療専門医および精神科専門医のそれぞれの知見よりダントロレンおよびベンゾジアゼピン（BZ）を同時に投与開始する診断的治療において悪性緊張病と診断した1例を経験した。
破傷風回復期に両側横隔膜麻痺を呈した1例(Diaphragmatic paralysis during recovery from tetanus: a case report)
Authors: 佳代子 原田 , 靖卓 古賀 , 雄史 八木 , 昌樹 戸谷 , 浩太郎 金田 , 基 藤田 , 良介 鶴田 
Published: June 2023

要旨破傷風はClostridium tetaniが産生する毒素による筋強直・攣縮を特徴とし，急性期に咽喉頭・呼吸筋の痙性麻痺に伴う呼吸不全を来す。今回我々は，破傷風回復期に横隔膜の弛緩性麻痺によるII型呼吸不全を呈した稀な症例を経験した。症例は80歳代の女性。嚥下障害と呼吸困難を主訴に紹介となった。約3週間前に左母指化膿創の治療歴があり，開口障害・頸部筋強直とあわせて破傷風と診断した。咽喉頭攣縮・誤嚥による呼吸不全を認め，気管挿管し人工呼吸を開始した。自発呼吸を温存した人工呼吸を行い，第10病日には筋強直の改善に伴い抜管した。しかし，直後からII型呼吸不全を呈し，咽喉頭攣縮・誤嚥の持続と判断して再挿管した。その後に気管切開を行い，第13病日に人工呼吸器から離脱したが，やはりII型呼吸不全のため再装着となった。胸部X線写真で新規両側横隔膜挙上を認め，エコーでも横隔膜運動低下が見られたため，横隔膜麻痺と診断した。横隔神経伝導検査では複合筋活動電位減弱を認めたが，遠位潜時の延長は明らかではなかった。その後は自然に改善を認め，第23病日に人工呼吸器から離脱した。破傷風で筋強直・攣縮を伴わない呼吸不全を認める場合は，横隔膜麻痺による弛緩性麻痺も考慮すべきである。
Cattell–Braasch法とmodified Mattox法の併用が有用であった外傷性下膵十二指腸動脈損傷の1例(Management of traumatic inferior pancreaticoduodenal artery injury: use of the Cattell–Braasch and modified Mattox maneuvers)
Authors: 良平 小崎 , 智 岡 , 理 赤坂 , 茂 山岸 , 英明 阿南 
Published: June 2023

要旨　74歳の男性。歩行中に乗用車に衝突され当院搬送となった。来院時ショック状態でfocused assessment with sonography for trauma（FAST）陽性であり，腹腔内出血による出血性ショックと診断した。直ちに気管挿管と緊急輸血，resuscitative endovascular balloon occlusion of the aorta（REBOA）留置を行い，緊急開腹術を行った。5点パッキング後，膵頭部後腹膜の膨隆を認めたため，Cattell–Braasch法を施行した。膵鉤部が挫滅し上腸間膜静脈から出血していたため，可及的に縫合し止血した。タオルパッキングを行いopen abdomen management（OAM）とした。術後の造影CT検査では，膵アーケードからの血管外漏出を認めたため，interventional radiology（IVR）を施行して下膵十二指腸動脈損傷と診断し，血管塞栓術を施行した。48時間後の計画的再手術でも膵頭部背側からの持続出血を認めたため，modified Mattox法を施行し，上腸間膜動脈根部の視野を確保し下膵十二指腸動脈を結紮止血した。その後の経過は良好で後遺症なく社会復帰した。外傷性膵損傷は血管損傷を合併すると死亡率が高いとされ，迅速な出血制御が救命において重要である。血管損傷を伴う膵損傷に対しては，左右からの授動を行うことで十分な視野を確保することができ，安全な血管処理ができる可能性がある。
Combined use of sensory methods for the selection of root, tuber and banana varieties acceptable to end‐users
Authors: Bechoff Aurélie , Adinsi Laurent , Ngoh Newilah Gérard , Nakitto Mariam , Deuscher Zoé , Ssali Reuben , Chijioke Ugo , Khakasa Elizabeth , Nowakunda Kephas , Bouniol Alexandre , Dufour Dominique , Bugaud Christophe 
Published: June 2023

AbstractBACKGROUNDThe assessment of user acceptability in relation to crop quality traits should be a full part of breeding selection programs. Our methodology is based on a combination of sensory approaches aiming to evaluate the sensory characteristics and user acceptability of root, tuber and banana (RTB) varieties.RESULTSThe four‐stepped approach links sensory characteristics to physicochemical properties and end‐user acceptance. It starts with the development of key quality traits using qualitative approaches (surveys and ranking) and it applies a range of sensory tests such as Quantitative Descriptive Analysis with a trained panel, Check‐All‐That‐apply, nine‐point hedonic scale and Just‐About‐Right with consumers. Results obtained on the same samples from the consumer acceptance, sensory testing and physicochemical testing are combined to explore correlations and develop acceptability thresholds.CONCLUSIONA combined qualitative and quantitative approach involving different sensory techniques is necessary to capture sensory acceptance of products from new RTB clones. Some sensory traits can be correlated with physicochemical characteristics and could be evaluated using laboratory instruments (e.g. texture). Other traits (e.g. aroma and mealiness) are more difficult to predict, and the use of a sensory panel is still necessary. For these latter traits, more advanced physicochemical methods that could accelerate the breeding selection through high throughput phenotyping are still to be developed. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Hunting and seagrass affect fall stopover Canada goose distribution in eastern Canada
Authors: Leblanc Mélanie‐Louise , Hanson Alan , Leblon Brigitte , LaRocque Armand , Humphries Murray M. 
Published: June 2023

AbstractCanada geese (Branta canadensis) migrating along coastal flyways are reliant on natural coastal ecosystems. Within these stopover sites, eelgrass (Zostera marina), the most common and widespread seagrass species in North America, is an important food resource for migrating waterfowl. Given the growing anthropogenic pressure on coastal ecosystems, geese migrating along coastal regions may find it increasingly difficult to access suitable stopover sites where food is abundant and human disturbance is low. We assessed the influence of hunting and eelgrass on the spatiotemporal distribution of Canada geese in the Tabusintac Bay, New Brunswick, Canada, a wetland of international importance. We surveyed Canada geese at 6 stations from mid‐September to late October, 2016 and 2017. We used 2‐part hurdle models consisting of generalized linear mixed models with binomial and negative binomial response distributions to model Canada geese presence and abundance, respectively, in relation to eelgrass abundance, distance to the mainland coastline, water depth, and tidal conditions in 3 different hunting intensity periods. Eelgrass abundance is a significant predictor of Canada geese presence early in the season, when hunting activity is low. At the onset of the hunting period, geese shifted diurnal distribution to areas farther offshore, indicating a response to avoid disturbance, and the abundance of Canada geese increased with increasing eelgrass availability, emphasizing the importance of eelgrass as a food source during fall migration in that region. Thus, our results highlight the effects of human disturbance and eelgrass abundance in influencing stopover behavior of Canada geese during fall migration in eastern Canada.
Cofinal types on ω2
Authors: Kuzeljevic Borisa , Todorcevic Stevo 
Published: June 2023

AbstractIn this paper we start the analysis of the class , the class of cofinal types of directed sets of cofinality at most ℵ2. We compare elements of using the notion of Tukey reducibility. We isolate some simple cofinal types in , and then proceed to find some of these types which have an immediate successor in the Tukey ordering of .
A Comprehensive Monte Carlo Model of the Grafting of Maleic Anhydride onto Polypropylene with Experimental Validation
Authors: Romero Pietrafesa Tomás , Brandolin Adriana , Sarmoria Claudia , Asteasuain Mariano 
Published: June 2023

AbstractA Monte Carlo model is employed to investigate the grafting of maleic anhydride onto polypropylene using a peroxide initiator. The study aimed to develop a comprehensive model that considered a very detailed kinetic mechanism, including chain transfer to polymer, homopolymerization as well as several copolymer reactions. The relative importance of these reactions is evaluated using a sensitivity analysis, which identified homopolymerization, β‐scission, chain grafting, and termination by disproportionation as the most influential reactions. The kinetic constants of these reactions are tuned to fit reported experimental data using the Surface Response Method. The model considers a pseudo‐homogeneous reaction medium and predicts average molecular weights, degree of grafting, molecular weight distribution, and grafting distribution. Furthermore, model simulations provided useful information about the impact of initial concentrations of reactants and reaction time on the molecular properties of the grafted polymer.
Can you breathe yourself to a better pelvic floor? A systematic review
Authors: Bø Kari , Driusso Patricia , Jorge Cristine Homsi 
Published: June 2023

AbstractIntroductionSome authors suggest that breathing exercises should be recommended instead of or in combination with pelvic floor muscle training (PFMT) to prevent and treat urinary incontinence (UI) and pelvic organ prolapse (POP).AimsThe primary aim of the present study was to investigate the evidence for breathing as an intervention alone or in addition to PFM contraction in treatment of UI and POP.Materials & MethodsThis systematic review included short‐term experimental studies and randomize controlled trials (RCTs) indexed on PubMed, EMBASE, and PEDro database. A form was used to extract data that was analyzed qualitatively due to the heterogeneity in interventions and outcome measures of the included studies. The individual methodological quality of RCTs was analyzed using the PEDro scale.ResultsA total of 18 studies were included, 374 participants from short‐term experimental studies and 765 from nine RCTs. PEDro score varied from 4 to 8. Activation of the PFM during expiration was significantly less than during a PFM contraction. In general, the RCTs showed that training the PFM is significantly more effective to improve PFM variables and UI and POP than breathing exercises, and that adding breathing exercises to PFMT have no additional effect.ConclusionThis systematic review indicates that the evidence for incorporating breathing exercise in clinical practice in addition to or instead of PFMT is scant or non‐existing, both based on short‐term experimental studies and small RCTs.
Satisfaction and perceived impact of virtual learning during COVID‐19 lockdown: A case study of an online nursing research conference
Authors: Adesuyi Emmanuel O. , Akingbade Oluwadamilare , Tola Yetunde O. , Otun Oluwadamilola , Faleti Damilola M. , Fawole Israel O. , Faleti Daniel D. , Dairo Emmanuel A. , Sado Olamide , Adefehinti Pelumi , Adewa Taiwo Olubunmi 
Published: June 2023

AbstractAimThis study aimed to assess nurses' satisfaction and perceptions of the impact of virtual learning.DesignA descriptive cross‐sectional survey.Method236 nurses attending an online conference from several parts of Nigeria participated in the study. Analysed data were summarized and presented in tables and graphs, while linear regression was used to measure the associations.ResultsMost of the respondents perceived the programme as highly impactful. All three domains: learner‐content interaction (p = 0.020), learner–instructor interaction (p = 0.000) and learner–learner interaction (p = 0.000), were found to be statistically significantly associated with the perceived impact of the programme, and thus statistically significant predictors of the effects of online learning (p = 0.02), (F = 5.471). Conclusively, the Interaction of learners with learning content, lecturers and other learners was seen as determinants of an effective and impactful online education. It is recommended that nursing training institutions embrace online learning either as the leading platform or as an adjunct to a face‐to‐face method.
Synthesis of trimethylolphosphine carbamate and its flame retardant application in cotton
Authors: Ma Xueyan , Liu Bingqing , Hao Yongbing , Guo Xing , Liu Lixia , Wang Jia , Chao Shujun , Shan Linlin , Shang Xuefang 
Published: June 2023

AbstractA novel free‐halogen flame retardant (trimethylolphosphine carbamate, THPON) was synthesized through the simple reaction between tetrakis(hydroxymethyl) phosphonium chloride and urea. Small molecule THPON could infiltrated the cotton fibers and grafted on cotton cellulose by amide bond. What is more, THPON did not change the inherent crystal structure of cotton because it infiltrated into the amorphous region of cotton. THPON‐treated cotton was easily decomposed into phosphoric acid or polyphosphate at lower temperature and exhibited good flame retardancy due to the N/P synergistic effect. Compared to control, the heat release rate of THPON‐treated cotton increased slower, indicating that a protective carbon layer formed and acted as a barrier. In addition, THPON displayed the low cytotoxicity and biosafety. The development and properties of THPON could provide an important data for the further application in the industry.
Sanguisorba officinalis L. promotes diabetic wound healing in rats through inflammation response mediated by macrophage
Authors: Song Jianying , Zeng Jing , Zheng Silin , Jiang Nan , Wu Anguo , Guo Shengming , Ye Rupei , Hu Lixin , Huang Feihong , Wang Long , Xiaogang Zhou , Liu Bo , Wu Jianming , Chen Qi 
Published: June 2023

AbstractSanguisorba officinalis L., a traditional Chinese medicine, is frequently used to treat burns and scalds. But even so, it is unknown whether S. officinalis L. can accelerate diabetic wounds (DW) healing. Here, to bridge the gap, we employed in vivo and in vitro evaluations to assess the positive effect of S. officinalis L. ethanol extract (ESO) on DW. Results demonstrated that ESO dramatically improved the DW healing rate. With ESO treatment, the inappropriately elevated levels of IL6, IL1β and TNFα in DW were reduced, while the expression of IL10 was increased, indicating that the abnormal inflammation in DW was also under control. Moreover, the abnormally elevated expression of CD86 was significantly inhibited and the expression of CD206 was significantly up‐regulated following treatment with ESO. The global level of NF‐κB protein was not affected by ESO treatment, but it suppressed the expression of phosphorylated NF‐κB and prevented its nuclear entry. In addition, in RAW264.7 cells activated with lipopolysaccharide (LPS), the expression of NLRP3, Caspase1 and IL1β were significantly diminished following ESO treatment. In conclusion, ESO was proved to be a promising treatment for DW healing due to its potential to accelerate the healing process by suppressing the inflammatory response. This was achieved by increasing the ratio of M2 to M1 polarization through blocking the NF‐κB/NLRP3 signaling pathway.
Integration frameworks and intelligent research in dynamic fault tree: A comprehensive review and future perspectives
Authors: Zhu Chengyuan , Jiang Yajie , Liu Guangyu , Zhang Tianyuan 
Published: June 2023

AbstractDynamic fault tree (DFT) is designed to conduct risk assessment studies of complex systems. With the development of intelligent and network technology, risk assessment technology faces a leap forward development. The requirements for improving system safety are being recognized. On the one hand, research on DFT is exploring the integration with different methods. On the other hand, DFT method becomes more intelligent. The purpose of this paper is to identify the feasibility and effectiveness of different integration frameworks. To achieve this goal, a suitable review process is proposed. This paper comprehensively reviews and proposes future perspective the research status of intellectualization in DFT, and focuses on the different types of integration framework of DFT, modeling technology and algorithm optimization, and the support of computer‐aided analysis. Theoretical contributions, frameworks features, and the development process of computer intelligent analysis in the scientific and technical literature are carefully reviewed. Finally, the challenges in future research are summarized to promote the development of intelligent evaluation.
Hydrogeomorphological processes and plant invasion. What interactions in the case of Asian knotweeds along the Herault River (France)?
Authors: Didier Marie , Borgniet Laurent , Le Bouteiller Caroline , Evette André , Boyer Mireille , Dommanget Fanny 
Published: June 2023

AbstractConsidered one of the five major threats to biodiversity worldwide, Invasive Alien Species (IAS) particularly threaten riparian ecosystems. Among the IAS found on riverbanks, Asian knotweeds (Reynoutria spp. including R. japonica Houtt.; R. sachalinensis [F.Schmidt] Nakai and the hybrid R. x bohemica Chrtek & Chrtkova) can barely be controlled as, once established, they disperse easily along stream banks via rhizome or stem fragments transported by water. However, the hydrogeomorphological processes underlying the establishment of Asian knotweeds are poorly understood. The objective of this study was to describe and model the hydrogeomorphological preferences of Asian knotweeds along a Mediterranean river. Based on exhaustive presence/absence surveys, we implemented two models related to the presence of Asian knotweeds: (1) at the river reach scale and (2) at the finer scale of the alluvial bar. Areas of low curvature identified as convex banks and the central parts of alluvial bars appear to be more susceptible to knotweed establishment. Highly disturbed areas were less favorable to maintaining plant species, including Asian knotweeds, while less disturbed areas with denser plant cover were more favorable to Asian knotweeds. The results seem to indicate a trade‐off hypothesis in the knotweed establishment strategy between hydrogeomorphological constraints and strong interspecific competition. Analyzed in the light of the current literature, our final models are designed to integrate hydrogeomorphological processes in order to provide an operational tool to help river managers locate the areas most susceptible to knotweed invasion and with important implications for managing these species in riparian ecosystems.
Comparision of NH3−SCR Activity over Cu‐Ce‐La/MCM‐49 and Cu‐Ce‐La/MCM‐22 Zeolites
Authors: Zhang Zhen , Yang Jian , Cui Jinxing , Li Zhifang , Yang Changlong , Ma Yuanyuan , Zhang Qian 
Published: June 2023

AbstractThe addition of La onto Cu‐Ce modified MWW type zeolite (MCM‐49 and MCM‐22) catalysts were synthesized by ion exchange process and the effect of different support (MCM‐49 and MCM‐22) on the activity was also discussed for ammonia selective catalytic reduction of NOx (NH3−SCR). The addition of La can significantly improve the catalytic performance of Cu‐Ce/MCM‐49. Furthermore, the addition of La can also facilitate electron transfer by the cycle of oxidation of Cu2++Ce3+→Cu++Ce4+ for Cu‐Ce‐La/MCM‐49. The electron transfer is beneficial to “FAST SCR” in that it can promote the conversion of NO to NO2, thus improving denitrification performance. Moreover, La can also provide the excellent surface acidity, which is favorable for the generation of oxygen vacancies. Compared with Cu‐Ce‐La/MCM‐22, Cu‐Ce‐La/MCM‐49 catalyst exhibited better SCR activity within 200–450 °C on account of the good redox performance and the more Ce3+ content. In addition, Ce3+ can generate oxygen vacancies, thereby enhancing the catalytic performance. More than anything, Cu‐Ce‐La/MCM‐49 has excellent sulfur tolerance.