bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship balance of hand grip strength and body balance to archry ability
Authors: Prasetyo Heru , Siswantoyo  , Prasetyo Yudik , Susanto  
Published: March 2023

Introduction. Archery is a static sport that requires good physical strength. This physical strength can affect the achievement of an archery athlete. Physical strength includes hand grip strength and body balance. One way to measure grip strength is to use a handgrip dynamometer. Meanwhile, to measure the balance of the body can use the stock body balance test. Then the sample did a test shooting of 36 arrows with a shooting range of 15 meters. Purpose. this study was to determine the relationship between hand grip strength and body balance with the ability to shoot archery at a distance of 15 meters. Methods. This research is a descriptive-analytic study with a cross-sectional design. The research was conducted at the Archery Training Center, Sleman Regency, Yogyakarta Special Region, Indonesia. The population sample is 60 people aged 12-13 years consisting of 34 boys and 26 girls. The data obtained was then tested for Pearson product-moment correlation and multiple regression correlation tests using the Statistical Product and Service Solutions (SPSS) application version 26. Results. The SPSS analysis test showed that there was a significant relationship between grip strength and archery skills at a distance of 15 meters with a significance value of p = 0.000 (p < 0.05) with a correlation coefficient of 0.446. Body balance is also related to archery skills at a distance of 15 meters with a significance value of p = 0.043 (p < 0.05) with a correlation coefficient of 0.262. Meanwhile, in the multiple correlation test, the results obtained were p = 0.001 (p < 0.05) with a correlation coefficient of 0.480. Conclusion. Based on the results and discussion above, it can be concluded that there is a relationship between hand grip strength, body balance, and archery skills at a distance of 15 meters in junior archery athletes in Sleman Indonesia.
حماية التصرفات القانونية وإثباتها عبر تطبيق الذكاء الاصطناعي
Authors: مصطفى الأسيوطي أيمن 
Published: March 2023

لا شك في أنّ العصر الحالي هو عصر تطبيقات الذكاء الاصطناعي بأنواعها وصورها المختلفة[1]، كونها باتت جزءاً لا يتجزأ من حياتنا وعلاقاتنا اليومية، وإن كانت مسألة استيعاب وتنظيم القواعد القانونية لمختلف المراكز التي نتجت عن التكنولوجيا الحديثة في صورتها التقليدية تقتصر على الابتكارات، التي لم تُثِر الكثير من الإشكالات[2]؛ إلا أن المفهوم الحديث لتكنولوجيا الذكاء الاصطناعي قد أدى إلى ظهور علاقات ومراكز جديدة في مختلف المجالات. وما خلفته من إيجابيات وسلبيات على كافة المجتمعات الإنسانية أثبتت عدم قدرة القواعد القانونية السارية على استيعابها وتنظيمها.
إنّ محلّ الإثبات ليس هو الحق ذاته مهما كانت طبيعته شخصياً كان هذا الحق أو عينياً، بل إن ما يقصد بمحل الإثبات هو: المصدر الذي ينشئ هذا الحق. وهذا المصدر إما أن يكون تصرفاً قانونياً أو واقعة مادية؛ لذلك يتعين على صاحب الحق إثبات مصدر حقّه[3].
والصلة بين الإثبات وحماية الحق وثيقة واضحة؛ حيث إن عجز المدعي عن إثبات حقه الشخصي أو العيني يترتب عليه بالضرورة فقدانه له، حتى وإن كان معترفاً به ومحمياً قانوناً. وعلى أساس ذلك فإّن مسألة الإثبات تحتّل حيزاً هاماً في مجال تطبيق الذكاء الاصطناعي.

[1] د. رانيا صبحي محمد عزب: العقود الرقمية في قانون الإنترنت "دراسة تحليلية مقارنة في الفقه والتشريعات العربية والأميركية والأوروبية"، دار الجامعة الجديدة، الإسكندرية، 2012، ص 109.
[2] للباحث كتاب بعنوان النظام القانوني للبثّ الفضائي عبر الأقمار الصناعية "دراسة مقارنة"، مركز الدراسات العربية للنشر والتوزيع، القاهرة، 2019، ص 46.
[3] راجع تفصيلاً د. سحر عبد الستار إمام: انعكاسات العصر الرقمي على قيم وتقاليد القضاء، بحث منشور بالمجلة المصرية للدراسات القانونية والاقتصادية، العدد العاشر، مصر، يناير 2018، ص 80.
الرقابة القضائية من خلال دعوى بطلان حكم التحكيم
Authors: عبدالواحد  إبراهيم هيثم 
Published: March 2023

الحمد لله رب العالمين، والصلاة والسلام على سيد الخلق نبينا محمد وعلى أهل بيته الطيبين الطاهرين وبعد...
بعد ان كانت القوة في المجتمعات القديمة وسيلة لاقتضاء الحقوق والمراكز القانونية والدفاع عنها، ظهر التحكيم باعتباره اتفاقاً على طرح النزاع على شخص معين أو أشخاص معينين ليفصلوا فيه من دون المحكمة المختصة، وهو نظام قانوني وجد منذ القدم فقد عرفته مصر القديمة وبابل وأشور، كما عرف لدى قدماء الاغريق ولدى الرومان الذين قالوا: (انه غير القضاء).
وقد عرف العرب قبل الاسلام نظامين للفصل بين الخصومات: نظام القضاء (الحسبة)، ونظام التحكيم، اذ يوجد نظام التحكيم في المجتمعات القبلية، وكذلك في المجتمعات المدنية التي لا توجد فيها سلطة مركزية قوية ويستمد الفرد المحكم سلطته في الحكم من اختيار الخصمين له وحكمه لا ينفذ قهراً، وانما برضاء المحكوم عليه.
II Congreso Internacional de Educación en Enfermería. “Sustentabilidad e internacionalización hacia una educación integral: trascendiendo límites geográficos”
Authors: Villalobos Guiza Margareth Nerly , Sanabria Hernández Nidia 
Published: March 2023

Introducción: La educación continua juega un papel importante en la calidad de la gestión del cuidado enfermero, les permite a los profesionales mejorar sus conocimientos, actualizarse e investigar en temas modernos y acorde a las necesidades presentes. Objetivo: Promover el intercambio de conocimientos dentro de la comunidad de enfermería mediante la organización de un congreso que incluya presentaciones, estudios basados en la evidencia y novedades científicas. Metodología: Congreso organizado por la Red Latinoamericana de Educación en Enfermería bajo modalidad virtual, sincrónico y asincrónico. Desarrollado del 20 al 22 de octubre del 2022, con una duración de 40 horas académicas. Resultados: 50 profesionales de enfermería realizaron ponencias magistrales, distribuidas en 6 ejes temáticos, además de la participación de 18 autores de distintos países en semillero de investigación con su respectivo resumen de investigación y ponencia. Conclusiones: El congreso reunió instituciones, enfermeros, estudiantes, docentes generando aporte significativo en la gestión del cuidado enfermero, demostró la capacidad de trabajo en equipo, abatiendo esquemas y fronteras.
MINI REVIEW: WIRELESS CHARGING SEBAGAI INOVASI PENGEMBANGAN TEKNOLOGI ELEKTROMAGNETIK DALAM MENUJU ERA SOCIETY 5.0
Authors: Rezeki Yulianto Agung , Zahra Aisha , Kamilla Amanda Alya , Ramadhani Fadhila 
Published: March 2023

Wireless charger merupakan teknologi yang dapat mentransfer energi melalui celah udara tanpa menggunakan kabel. Teknologi ini penting dalam menyongsong perkembangan teknologi lain pada industri 5.0 karena keefektifannya. Namun, dalam pemahaman dan pengembangan terkait dengan wireless charger masih sangat minim, terutama di Indonesia. Oleh karena itu, pada artikel ini kami menyajikan ulasan terkait dengan wireless charger, perkembangan wireless charger wireless sebagai penerapan elektromagnetik, serta memaparkan kelebihan dan kekurangan wireless charger.
An Assessment of Biodiesel Production from Three Species of Micro Algae (Chlamydomonas reinhardtii, Chroococcus species and Ankistrodesmus falcatus)
Authors: Laurelta Tudararo-Aherobo , Oghenekaro Itoro Lilian 
Published: March 2023

Aim: Over dependence on fossil fuels has triggered environmental and economic concerns, creating an ultimate need to redirect towards renewable energy options. Hence, the study on biodiesel production from algal biomass.
Study Design: Modified open pond culture system was applied in the biomass culture and growth was monitored via pH and turbidity.
Place and Duration of Study: Study was done in the laboratory of the Department of Environmental Management and Toxicology, Federal University of Petroleum Resources, Effurun between June 2020 and July 2021.
Methodology: Soxhlet extraction was applied in algal oil extraction. Alkali-mediated transesterification of algal oil blends into biodiesel was conducted. Biodiesel blends were characterized physically and spectroscopically for fuel properties and chemical position. The synthesis and fuel properties of biodiesels from three micro algal species: Chroococcus sp, Ankistrodesmus falcatus, and Chlamydomonas reinhardtii were conducted. Due to low algal oil yield, characterization of four types of hybrid oils were prepared: 100 percen(%)t lavender oil (100LO), 10% Ankistrodesmus falcatus oil plus 90% LO (10AN90LO), 10% Chlamydomonas reinhardtii oil plus 90% LO (10CHL90LO), and 10% Chroococcus sp oil plus 90% LO (10CHR90LO).
Results: The synthesis and fuel properties of biodiesels from the micro algal species: Chroococcus sp, Ankistrodesmus falcatus, and Chlamydomonas reinhardtii gave a percentage yield of algal oil of 29.6%, 23.4% and 15.5%, respectively. The percentage yield of biodiesel from 10AN90LO, 10CHL90LO, 10CHL90LO was 66.7%, 61.7% and 50.0%, respectively. Gas Chromatography-Mass Spectrometry(GC-MS) analysis revealed presence of four fatty acid methyl and vinyl esters namely; hexadecanoic acid methyl ester, octadecadienoic acid methyl ester, methyl stearate, carbonic acid eicosyl vinyl ester and carbonic acid, tetradecyl vinyl ester. Fourier transform infrared spectroscopy(FTIS) confirms that chemicals produced are esters.
Conclusion: Fuel properties of biodiesel from these selected algal strains appear appreciable when compared to standard limits. Blends with petroleum diesel showed great potential for use in diesel engines.
Effect of Disulfiram and Copper Plus Chemotherapy vs Chemotherapy Alone on Survival in Patients With Recurrent Glioblastoma
Authors: Werlenius Katja , Kinhult Sara , Solheim Tora Skeidsvoll , Magelssen Henriette , Löfgren David , Mudaisi Munila , Hylin Sofia , Bartek Jiri , Strandéus Michael , Lindskog Magnus , Rashid Havyan Bahroz , Carstam Louise , Gulati Sasha , Solheim Ole , Bartek Jiri , Salvesen Øyvind , Jakola Asgeir Store 
Published: March 2023

ImportanceDisulfiram has demonstrated broad antitumoral effect in several preclinical studies. One of the proposed indications is for the treatment of glioblastoma.ObjectiveTo evaluate the efficacy and safety of disulfiram and copper as add-on to alkylating chemotherapy in patients with recurrent glioblastoma.Design, Setting, and ParticipantsThis was a multicenter, open-label, randomized phase II/III clinical trial with parallel group design. Patients were recruited at 7 study sites in Sweden and 2 sites in Norway between January 2017 and November 2020. Eligible patients were 18 years or older, had a first recurrence of glioblastoma, and indication for treatment with alkylating chemotherapy. Patients were followed up until death or a maximum of 24 months. The date of final follow-up was January 15, 2021. Data analysis was performed from February to September 2022.InterventionsPatients were randomized 1:1 to receive either standard-of-care (SOC) alkylating chemotherapy alone, or SOC with the addition of disulfiram (400 mg daily) and copper (2.5 mg daily).Main Outcomes and MeasuresThe primary end point was survival at 6 months. Secondary end points included overall survival, progression-free survival, adverse events, and patient-reported quality of life.ResultsAmong the 88 patients randomized to either SOC (n = 45) or SOC plus disulfiram and copper (n = 43), 63 (72%) were male; the mean (SD) age was 55.4 (11.5) years. There was no significant difference between the study groups (SOC vs SOC plus disulfiram and copper) in 6 months survival (62% [26 of 42] vs 44% [19 of 43]; P = .10). Median overall survival was 8.2 months (95% CI, 5.4-10.2 months) with SOC and 5.5 months (95% CI, 3.9-9.3 months) with SOC plus disulfiram and copper, and median progression-free survival was 2.6 months (95% CI, 2.4-4.6 months) vs 2.3 months (95% CI, 1.7-2.6 months), respectively. More patients in the SOC plus disulfiram and copper group had adverse events grade 3 or higher (34% [14 of 41] vs 11% [5 of 44]; P = .02) and serious adverse events (41% [17 of 41] vs 16% [7 of 44]; P = .02), and 10 patients (24%) discontinued disulfiram treatment because of adverse effects.Conclusions and RelevanceThis randomized clinical trial found that among patients with recurrent glioblastoma, the addition of disulfiram and copper to chemotherapy, compared with chemotherapy alone, resulted in significantly increased toxic effects, but no significant difference in survival. These findings suggest that disulfiram and copper is without benefit in patients with recurrent glioblastoma.Trial RegistrationClinicalTrials.gov Identifier: NCT02678975; EUDRACT Identifier: 2016-000167-16
Programmed Cell Death Ligand 1 Expression on Immune Cells and Survival in Patients With Nonmetastatic Head and Neck Cancer
Authors: Blažek Tomáš , Petráš Marek , Knybel Lukáš , Cvek Jakub , Soumarová Renata 
Published: March 2023

ImportanceThe failure or success of radical treatment in patients with head and neck squamous cell carcinoma (HNSCC) is associated with many known and unknown factors; hence, there is a search for further prognostic markers to help optimize therapeutic strategy and improve treatment outcomes.ObjectiveTo assess the association of programmed cell death ligand 1 (PD-L1) expression on immune or tumor cells, including its composite expression on both cell types, with overall survival (OS) or specific survival.Data SourcesMEDLINE, Embase, PQSciTech, and HCAPlus databases were systematically searched for cohort studies focused on the prognostic role of PD-L1 expression in patients with HNSCC in curative stages of the disease. Search results generated publications from January 1, 2010, to January 6, 2023.Study SelectionOf 3825 publications identified, a total of 17 cohort studies in the English language met inclusion criteria of this systematic review and meta-analysis. Eligible studies reported adjusted hazard ratios (aHRs) with 95% CIs for the association of PD-L1 expression levels with OS and arbitrary specific survival.Data Extraction and SynthesisData from studies were extracted independently by 2 researchers strictly adhering to the Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guidelines and recommendations. The risk of bias was assessed using the Quality in Prognosis Studies tool and Newcastle-Ottawa Scale. Pooled effect estimates were obtained using a random-effect or fixed-effect model based on homogeneity of studies.Main Outcomes and MeasuresThe primary outcome was to investigate whether there was an association between PD-L1 expression on immune or tumor cells and OS.ResultsIn 17 cohort studies of the association of PD-L1 expression with survival in 3190 patients with HNSCC, high PD-L1 expression on immune cells was associated with a favorable OS (pooled aHR, 0.39; 95% CI, 0.25-0.59). There was no association between composite PD-L1 expression on immune and tumor cells and OS (pooled aHR, 0.79; 95% CI, 0.55-1.14) or between PD-L1 expressed only on tumor cells and OS (pooled aHR, 1.22; 95% CI, 0.87-1.70). A high level of PD-L1 expression on immune cells was associated with favorable specific survival (pooled aHR, 0.52; 95% CI, 0.38-0.72). There were no interactions between tumor location or type of primary treatment (ie, surgery vs radiotherapy or radiochemotherapy) and the association between PD-L1 expression and OS.Conclusions and RelevanceThis study’s findings suggest that PD-L1 expression on immune cells may serve as a new prognostic biomarker in patients with HNSCC. However, future studies may be warranted to verify this potential role given the limited number of studies on this topic conducted and published to date.
Plasma GFAP associates with secondary Alzheimer's pathology in Lewy body disease
Authors: Cousins Katheryn A. Q. , Irwin David J. , Chen‐Plotkin Alice , Shaw Leslie M. , Arezoumandan Sanaz , Lee Edward B. , Wolk David A. , Weintraub Daniel , Spindler Meredith , Deik Andres , Grossman Murray , Tropea Thomas F. 
Published: March 2023

AbstractObjectiveWithin Lewy body spectrum disorders (LBSD) with α‐synuclein pathology (αSyn), concomitant Alzheimer's disease (AD) pathology is common and is predictive of clinical outcomes, including cognitive impairment and decline. Plasma phosphorylated tau 181 (p‐tau181) is sensitive to AD neuropathologic change (ADNC) in clinical AD, and plasma glial fibrillary acidic protein (GFAP) is associated with the presence of β‐amyloid plaques. While these plasma biomarkers are well tested in clinical and pathological AD, their diagnostic and prognostic performance for concomitant AD in LBSD is unknown.MethodsIn autopsy‐confirmed αSyn‐positive LBSD, we tested how plasma p‐tau181 and GFAP differed across αSyn with concomitant ADNC (αSyn+AD; n = 19) and αSyn without AD (αSyn; n = 30). Severity of burden was scored on a semiquantitative scale for several pathologies (e.g., β‐amyloid and tau), and scores were averaged across sampled brainstem, limbic, and neocortical regions.ResultsLinear models showed that plasma GFAP was significantly higher in αSyn+AD compared to αSyn (β = 0.31, 95% CI = 0.065–0.56, and P = 0.015), after covarying for age at plasma, plasma‐to‐death interval, and sex; plasma p‐tau181 was not (P = 0.37). Next, linear models tested associations of AD pathological features with both plasma analytes, covarying for plasma‐to‐death, age at plasma, and sex. GFAP was significantly associated with brain β‐amyloid (β = 15, 95% CI = 6.1–25, and P = 0.0018) and tau burden (β = 12, 95% CI = 2.5–22, and P = 0.015); plasma p‐tau181 was not associated with either (both P > 0.34).InterpretationFindings indicate that plasma GFAP may be sensitive to concomitant AD pathology in LBSD, especially accumulation of β‐amyloid plaques.
Cation–Oxygen Bond Covalency: A Common Thread and a Major Influence toward Air/Water‐Stability and Electrochemical Behavior of “Layered” Na–Transition‐Metal‐Oxide‐Based Cathode Materials
Authors: Kumar Bachu Sravan , Pradeep Anagha , Srihari Velaga , Poswal Himanshu K. , Kumar Rahul , Amardeep Amardeep , Chatterjee Abhijit , Mukhopadhyay Amartya 
Published: March 2023

AbstractThis work evolves a universal strategy, toward simultaneously addressing the air/water‐instability and structural‐cum‐electrochemical instability of “layered” Na–transition‐metal (TM)–oxide‐based cathode materials for Na‐ion batteries, by way of varying the “interslab” spacing via tuning the TMO bond covalency. In this regard, model O3‐structured NaTMoxides, with varied “charge‐to‐size” ratio of the cation‐combination (viz., TM‐ + non‐TM‐ions) in the TM‐layer [i.e., (C:S)TM], are designed and subjected to structural characterizations, density‐functional‐theory‐based studies, air/water‐exposure studies, electrochemical cycling, and operando investigations. Such studies have yielded a clear correlation‐cum‐trend concerning lower (C:S)TM => lower TMO covalency => higher effective negative charge on O‐ion (which gets shared by both TM‐ and Na‐ions) => stronger‐cum‐shorter NaO bond => reduced “interslab” spacing => lower Na‐transport kinetics => suppressed spontaneous Na‐extraction upon air/water‐exposure => concomitant vastly improved air/water‐stability => suppressed/delayed O3 → P3 transformation during electrochemical Na‐extraction (i.e., charging) => concomitant vastly improved electrochemical cyclic stability. Furthermore, a critical d(ONaO)/d(OTMO) of ≈1.38 for the O3 structure, corresponding to the initiation of O3 → P3 transformation during desodiation/charging is revealed. NaTMO2s having higher initial (C:S)TMs reach this critical d(ONaO)/d(OTMO) earlier (i.e., upon minimized Na‐removal) and, thus, suffer from more transformations during continued desodiation/charge, resulting in structural‐cum‐electrochemical instability.
Association of changes in grip strength with second digit length adjusted for fourth digit length in young children
Authors: Abe Takashi , Abe Akemi , Loenneke Jeremy P. 
Published: March 2023

AbstractObjectivesThe factors involved in changes in grip strength (GS) during growth/development are not well known. Findings from cross‐sectional studies have indicated that digit lengths are associated with physical fitness, including GS. This study aimed to investigate the association of changes in GS over 1 year and the second (2D) and fourth (4D) digit lengths in young children using the 4D as a covariate.MethodsOne hundred and three young children (54 boys and 49 girls) performed maximum voluntary GS and ultrasound‐measured forearm muscle thickness measurements in the right hand. All participants completed the first measurement and underwent a second measurement 1 year after the first one. The 2D and 4D were taken on the palmar surface of the outstretched right hand at the second measurement.ResultsThe 2D was inversely associated with the change in GS (B = −2.1, p = 0.023) adjusted for all covariates. Girls had numerically lower adjusted changes in grip strength, although this was not statistically significant [−0.61 (−1.2, 0.02) kg]. When sex was removed from the model, the 2D remained inversely associated with the change in GS (B = −2.39, p = 0.011). Finally, when only adjusting for the 4D, the 2D was inversely associated with the change in GS (B = −3.07, p = 0.004).ConclusionThis study documented the association between changes in GS over 1 year and digit lengths in young children. The difference in children's digit length needs to be recognized as a factor involved in weak GS in children.
Cardiometabolic risk in young adults with Down syndrome
Authors: Manfredo Jacquelyn , Capone George , Yanek Lisa , McCarter Robert , Zemel Babette , Kelly Andrea , Magge Sheela N. 
Published: March 2023

AbstractStudies regarding cardiometabolic risk (CMR) for individuals with Down syndrome (DS) conflict. Our previous research in youth with DS, aged 10–20 years, found increased prevalence of dyslipidemia and prediabetes compared to matched peers without DS. Herein, we compare CMR in young adults with DS, aged 18–35 years, to a similar population‐based sample from the 2001–2018 National Health and Nutrition Examination Survey (NHANES). The group with DS had higher NonHDL‐C (mean DS 131.9 mg/dL; NHANES 126.1 p < 0.001), lower HDL‐C (DS 47.5 mg/dL; NHANES 52.2 p < 0.001), higher LDL‐C (DS 109.3 mg/dL; NHANES 105.4 p < 0.001), higher triglycerides (DS 102.9 mg/dL; NHANES 86.9 p < 0.001), but lower fasting glucose (DS 85.8 mg/dL; NHANES 95.2 p < 0.0001), lower HOMA‐IR (DS 2.17; NHANES 2.24 p = 0.0006), lower systolic (DS 109.7 mmHg; NHANES 114.6 p < 0.0001) and lower diastolic (DS 60.9 mmHg; NHANES 67.8 p < 0.0001) blood pressures. There was relationship of higher HDL‐C, triglycerides, glucose, systolic, and diastolic blood pressure with increasing BMI in the NHANES cohort which was dampened in the group with DS. These results indicate that more information is needed to guide clinicians in screening for CMR in individuals with DS.
Iron in blood cells: Function, relation to disease, and potential for magnetic separation
Authors: Barua Sowrav , Ciannella Stefano , Tijani Lukman , Gomez‐Pastora Jenifer 
Published: March 2023

AbstractIron in blood cells has several physiological functions like transporting oxygen to cells and maintaining iron homeostasis. Iron is primarily contained in red blood cells (RBCs), but monocytes also store iron as these cells are responsible for the recycling of senescent RBCs. Iron also serves an important role related to the function of different leukocytes. In inflammation, iron homeostasis is dependent on cytokines derived from T cells and macrophages. Fluctuations of iron content in the body lead to different diseases. Iron deficiency, which is also known as anemia, hampers different physiological processes in the human body. On the other hand, genetic or acquired hemochromatosis ultimately results in iron overload and leads to the failure of different vital organs. Different diagnoses and treatments are developed for these kinds of disorders, but the majority are costly and suffer from side effects. To address this issue, magnetophoresis could be an attractive technology for the diagnosis (and in some cases treatment) of these pathologies due to the paramagnetic character of the cells containing iron. In this review, we discuss the main functions of iron in blood cells and iron‐related diseases in humans and highlight the potential of magnetophoresis for diagnosing and treating some of these disorders.