bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of endobronchial needle aspiration during bronchoscopy in exophytic endobronchial lesions
Authors: Patil Shital , Gondhali Gajanan , Khule Shubhangi , Patil Deepak 
Published: May 2023

INTRODUCTION:
Globally, lung cancer is the leading cause of new cancer diagnosis and deaths. Despite advancement in diagnostic modalities lung cancer diagnosis is often delayed due to a lack of bronchoscopy facilities and techniques. In the present study, we have analyzed the role of bronchoscopy in the diagnosis of lung cancer with special emphasis on endobronchial needle aspiration (EBNA) cytology in comparison to other conventional diagnostic techniques (CDTs) such as bronchial wash (BW) and forcep biopsy (FB).

METHODS:
Prospective, observational study screened 1280 cases with suspected lung malignancy on a clinical and radiological basis. Bronchoscopy-guided techniques such as EBNA, BW, and FB are used in exophytic endobronchial lesions (EELs) in confirming the diagnosis of lung cancer and to find additive yield over other techniques such as BW and FB. Rapid on-site evaluation analysis of all EBNA samples done in pathology laboratory allied center. Finally, histopathology proven 810 lung malignancy cases are included in this study. Statistical analysis is done using Chi-square test.

RESULTS:
In the present study, 810 diagnosed lung cancer patients between 29 and 85 years of age group predominant males 59.25% (480/810) and smokers by addiction in 63.20% (512/810) cases. Presented with cough in 82.09% (665/810), clubbing in 56.17% (455/810) cases, and mass lesion in chest radiograph in 42.22% (342/810) cases. Anatomical location is documented on the right side of tracheobronchial in 59.01% (478/810) cases during bronchoscopy. The yield of FB and FB plus bronchial wash in EEL is 89.25% (723/810) and 93.08% (754/810), respectively. The yield of EBNA, EBNA plus bronchial wash, and EBNA plus FB in EEL is 64.56% (523/810), 67.28% (545/810), and 97.65% (791/810), respectively. Total yield of all fiberoptic bronchoscopy-guided procedures (EBNA + FB + BW) in EEL is 100%. Additional yield of EBNA in EEL over other CDTs is 6.92%. Sensitivity of FB and EBNA in diagnosing lung malignancy in EEL is 89.25% and 64.56%, respectively. FB is more sensitive technique than EBNA in EEL (P < 0.00001). Sensitivity of FB plus bronchial wash in EEL is 93.08% (754/810). Sensitivity of EBNA plus bronchial wash in EEL is 67.28% (545/810). Sensitivity of EBNA plus FB in EEL is 97.65% (791/810) (P < 0.00001).

CONCLUSIONS:
EBNA has documented very crucial role in diagnosing lung cancer in comparison to other CDTs. Although FB is a more sensitive test than EBNA in EEL in diagnosing disease, we have documented EBNA has significant additive yield in proportionate number of cases. EBNA is safe, sensitive, and cytology samples can give comparable results to histopathology.
Management of Vandhyatva w.s.r. to thin endometrium through Ayurveda- A single arm open labelled pilot clinical trial
Authors: Rupareliya Jalpa Deepak , Donga Shilpa , Gandhi Abhay Jayprakash 
Published: May 2023

Background:
The four essential factors of conception are Ritu (optimum period for conception), Kshetra (place of conception), Ambu (nutrition), and Beeja (healthy sperm and ovum). Kshetra denotes body as general and to be very specific, especially about the female reproductive system, it is Garbhashaya or the uterine cavity and function is Garbhadhana or conception. The endometrial factor is an important subset in infertility due to poor implantation.

Aims:
To evaluate the efficacy of Saubhagyanandana Ghrita Yonipichu (vaginal tampoon) and Jeevaniya Churna orally in the management of thin endometrium thickness and to evaluate its efficacy in the associate complains of menstrual abnormalities, i.e., irregularity of menstrual cycle, quantity, duration and pain.

Materials and methods:
It was a single-arm open labeled pilot clinical trial, a total of 15 female patients having endometrial thickness <7 mm on transvaginal sonography findings were included in the study. Each patient (n = 15) was given Saubhagyanandana Ghrita Yonipichu (10 mL for 6 days after cessation of menses, for 1 cycle) along with Jeevaniya Churna orally 10 g along with milk twice before meals for 30 days. Assessment of the study was done on Appelbaum's uterine scoring system for the reproduction (USSR) scoring pattern.

Results:
Results were analyzed by the paired' t-test for the objective parameters and Wilcoxon signed rank–sum test for the subjective parameters. A statistically highly significant difference (P < 0.001) was seen in endometrium thickness, layering, myometrial echogenicity, uterine Doppler flow, endometrial blood flow in zone 3, and total USSR score. Statistical significant difference (P < 0.05) was found in the menstrual abnormalities and a highly statistically significant difference (P < 0.001) was found in ovulation. One of the patients conceived after the treatment.

Conclusion:

Saubhagyanandana Ghrita Yonipichu (vaginal tampoon) and Jeevaniya Churna orally are effective in improving the thin endometrium.
Swasthya Assessment Scale (SAS)-Ayurveda based health assessment tool-insights on its development and validation
Authors: Ram Jaiprakash Bholanath , Yadav Babita , Ashwathykutty V. , Jameela Sophia , Ahmad Azeem , Thrigulla Saket Ram , Sharma Sakshi , Rana Rakesh K. , Singhal Richa , Rao Bhogavalli Chandrasekhara , Srikanth N. , Dhiman K. S. 
Published: May 2023

Introduction:

Ayurveda has a unique way of understanding the body, health, and diseases. Various determinants, including biological, ecological, medical, psychological, sociocultural, spiritual, and metaphysical factors, which depend on each other, have their role in determining health in Ayurveda. Currently, no validated health assessment scale, based on the principles of Ayurveda is available. This article, for the first time, reports the development, validation, and reliability testing of the Swasthya assessment scale - a health assessment tool developed in Ayurveda.

Materials and methods:
A thorough literature search and expert consultations were done to draft the items encompassing the concept of health in Ayurveda. A group of experts assessed the content validity of the drafted items. Cognitive de-briefing and pretesting were performed to modify the language and the content again. Reliability testing was done with an inter-observer agreement in a sample of 183 individuals.

Results:
The content validity index for items and the scale-level content validity index (S-CVI) were calculated. S-CVI for scale was excellent, with 85% agreement. The S-CVI/universal agreement was 0.45, and S-CVI/Average was 0.95. In inter-rater reliability, the percentage agreement was 73.7%. Pearson correlation coefficient was 0.808 showing a strong correlation.

Conclusion:
Following appropriate validation, the scale can be widely used in clinical practice to assess the patient's health status, guide the treatment plans, and monitor the progress of the health. It can also be used as a sensitive tool in the research of Ayurveda to assess the changes in patients brought about by Ayurveda interventions.
Comparison of intranasal midazolam-fentanyl with dexmedetomidine–fentanyl as pre-medication in the paediatric age group
Authors: Kaur Tripat , Kumar Parmod , Kundra Tanveer Singh , Kaur Ikjot 
Published: May 2023

Background & objectives:
Intranasal midazolam-fentanyl is commonly used as pre-medication in paediatric patients, but there is a risk of respiratory depression with this combination. Dexmedetomidine is a drug that preserves respiratory function. The objective of this study was to compare the efficacy of intranasal midazolam-fentanyl and dexmedetomidine-fentanyl in paediatric patients undergoing elective surgeries.

Methods:
Hundred children in the age group of 3-8 yr of American Society of Anaesthesiologists physical status grade 1 were randomized into two groups- group A received intranasal midazolam (0.2 mg/kg)-fentanyl (2 µg/kg) and group B received intranasal dexmedetomidine (1 µg/kg)-fentanyl (2 µg/kg) 20 min before induction of general anaesthesia. Heart rate and SpO2 were monitored. Sedation score, parental separation and response to intravenous cannulation were seen after 20 min. Children were monitored for 2 h for post-operative analgesia by Oucher’s Facial Pain Scale.

Results:
Sedation scores were satisfactory in both groups, although children in group A were more sedated than in group B. Parental separation and response to intravenous cannulation were comparable in both the groups. The two groups were also haemodynamically comparable intraoperatively. Post-operative heart rate was also comparable at all-time intervals in both the groups except for heart rate at 100 and 120 min which were more in group A. Group A experienced more post-operative pain as assessed by Oucher’s Facial Pain Scale as compared to group B. Children receiving intranasal dexmedetomidine-fentanyl had better post-operative analgesia as compared to those who received intranasal midazolam-fentanyl.

Interpretation & conclusions:
Both intranasal midazolam with fentanyl and intranasal dexmedetomidine with fentanyl provided satisfactory sedation. Both groups were comparable in separation reaction and response to intravenous cannulation with better post-operative analgesia in children receiving intranasal dexmedetomidine-fentanyl.
Posterior segment involvement in systemic lupus erythematosus – A series from South India
Authors: Babu Kalpana , Nanda Satabdi , Hegde Preeti , Rao Anand P , Jois Ramesh 
Published: May 2023

Purpose:
To report the spectrum of posterior segment manifestations and visual outcomes in a large series of patients with systemic lupus erythematosus (SLE).

Methods:
Retrospective study at a tertiary referral eye center in south India between 2016 and 2022.

Results:
Charts of 109 patients diagnosed to have SLE were retrieved from our medical database. Only nine cases of SLE (8.25%) had posterior segment involvement. The male: female ratio was 1:8. The mean age was 28 years. Unilaterality was the most common presentation in eight cases (88.89%). Lupus nephritis was the most common systemic presentation in five cases (55.56%). Antiphospholipid antibodies (APLA) positivity was seen in two cases (22.22%). Ocular manifestations included microangiopathy (cotton wool spots) in one case, occlusive retinal vasculitis with cotton wool spots in four cases (five eyes), optic disc edema with combined venous and arterial occlusion (one case), central retinal vein occlusion with cotton wool spots and hemorrhages (one case), macular edema (four cases), posterior scleritis with optic disc edema and exudative retinal detachment in the posterior pole (one case), and tubercular choroidal granuloma (one case). Treatment included systemic steroids, hydroxychloroquine sulfate (HCQS), and immunosuppression in all cases, blood thinners in two cases, and laser photocoagulation in four cases. HCQS-related retinal toxicity was not seen in any of the 109 cases. Ocular manifestation was the initial presentation of SLE in one case. Visual outcome was poor in three cases.

Conclusion:
Presence of posterior segment findings in cases with SLE may suggest a severe systemic disease. Early detection and aggressive treatment result in better visual outcomes. Ophthalmologists could play a vital role in guiding systemic therapy.
Impact of preoperative posterior segment evaluation on surgical intervention in camp patients: A retrospective analysis
Authors: Jain Priti , Ahuja Nisha 
Published: May 2023

Purpose:
To retrospectively study impact of preoperative posterior segment evaluation on surgical intervention in camp patients recruited for cataract surgery in Gujarat India.

Methods:
Retrospective analysis of six months data collected from hospital electronic medical record (EMR) system of 9820 admitted patients recruited from screening camp for cataract surgery from 1/10/2019 to 31/3/2020 in Tertiary Eye Hospital in Gujarat, India, has been done. Comprehensive clinical evaluation, of both anterior and posterior segment which included detailed history; best corrected visual acuity (BCVA); intraocular pressure measurement with non-contact tonometer (NCT) and when required with Goldman applanation tonometer; slit lamp examination; and fundus examination with + 90 diopter lens as well as indirect ophthalmoscope as and when indicated. In case there was no view of retina, a B-scan ultrasound was done to rule out any posterior segment pathology. Immediate surgical intervention done was assessed and results analyzed in percentage.

Results:
Cataract surgery was advised for 8390 patients (85.43%). Surgical intervention for management of glaucoma was done for 68 patients (0.692%). Retina intervention was done for 86 patients. Posterior segment evaluation changed immediate surgical plane of management for 154 (1.57%) patients.

Conclusion:
Comprehensive clinical evaluation is economical and should be mandatory especially in community services as comorbid conditions like glaucoma, diabetic retinopathy, retinal vein occlusion, and other varied posterior segment diseases contribute significantly to visual disability in elderly age group. It is difficult to follow these patients later if manageable comorbidity is not informed about and if indicated dealt simultaneously for visual rehabilitation of patient.
Five-Year Follow-up in Patients with Transobturator Tape – A Retrospective Observational Study
Authors: Verneker Ruchika A. , Mishra Vineet , Tutwala Nimish , Lamba Sunita 
Published: May 2023

Background:
Stress urinary incontinence (SUI) could be due to urethral hypermobility due to the weakening of the pelvic floor muscles which support the urethra and bladder or the intrinsic sphincter deficiency. The mid-urethral tape acts as an anchored pubo-urethral neo-ligament thus increasing the level of mid-urethral support. The purpose of this study is to evaluate the safety and efficacy of transobturator tape (TOT) for SUI at 5 years of follow-up.

Materials and Methods:
This was a retrospective observational single-arm study of 40 patients. Ten patients were lost to follow-up; hence, only 30 patients were included in the study. Patients who underwent TOT from 2010 to 2012 were followed up till December 2017. Patients were evaluated for early and late postoperative complications and efficacy of the tape at 5 years.

Results:
The mean age of the patients with SUI was 48.07 (standard deviation ± 9.38). About 76.66% (n = 23) of patients had only pure stress incontinence, whereas 23.3% of patients (n = 7) had mixed urinary incontinence (MUI). The cure rate in our study was 93.33% at 5 years. Out of the seven patients with MUI, urge incontinence was cured in 71.42% (n = 5). De novo urgency was observed in 6.6% (n = 2). No major complications such as bladder and bowel perforation, vascular hemorrhage, or mesh erosion were seen. Patient satisfaction was graded as excellent in 46.66% (n = 14), good in 30% (n = 9), and poor in 23% (n = 7).

Conclusion:
TOT for stress incontinence has a high cure rate and very good efficacy at 5 years. No major complications are seen when the procedure is performed by expert hands.
Salivary Menopausal Markers and Oral Health Status – A Hidden Hook Up
Authors: Soundarya B , Massillamani F , Kailasam S , Jayashree G , Narmadha N , Sornaa N 
Published: May 2023

Aim and Objectives:
The aim of our study was to evaluate salivary estradiol and salivary calcium in postmenopausal women with varying degrees of oral dryness. The primary objective was to establish the interrelationship between salivary parameters and oral health status among menopausal women and compare the same with premenopausal women and normal controls.

Materials and Methods:
The study included 60 women Group I consisted of healthy menstruating women between 25 and 34 years of age. In Group II premenopausal women between 35 and 45 years of age were present and Group III consisted of menopausal women between 45 and 60 years of age. Unstimulated saliva was collected from the participants and estradiol analysis was done using ELISA method and calcium analysis was done using Arsenazo III reaction using colorimetric method. The oral health status in these patients was determined by using xerostomia score, Russell's periodontal score, and oral hygiene index. The values obtained were subjected to statistical analysis and the results were derived.

Results:
On oral examination, most of them had poor oral hygiene, periodontal disease, and moderate to severe levels of xerostomia. Salivary estradiol levels were low and salivary calcium levels were high among postmenopausal women and as salivary estradiol levels decreased there was an increase in xerostomia scores and salivary calcium. And also as salivary calcium levels increased the periodontal disease scores increased. All parameters were within normal limits among healthy menstruating women.

Conclusion:
Saliva can be a preferred medium and an emerging alternative for serum to estimate estradiol and calcium levels. As a dentist, we have to educate them about the oral changes they will experience during menopause and emphasize its strong association between low estradiol levels. Oral hygiene instructions should be given for the maintenance of healthy periodontium. Menopausal women who experience severe postmenopausal symptoms can be identified and the dentist and gynecologist can work hand in hand to treat the symptoms of these women.
Pupillary dynamics and accommodative response in mild traumatic brain injury
Authors: Dutta Pritam , Atiya Ayisha , Vittal Smita , Ambika S. , Hussaindeen Jameel Rizwana 
Published: May 2023

Abstract

PURPOSE:
To measure the pupillary dynamics and accommodative response in individuals with mild traumatic brain injury (mTBI) as compared to age-matched controls.

MATERIALS AND METHODS:
This prospective comparative study was carried out at the neuro-optometry clinic of a tertiary eye care hospital. Sixty-three subjects with a history of mTBI and ninety age-matched controls were enrolled in this study. Subjects in the age range of 18–35 years were included in the study. A comprehensive neuro-optometric assessment was performed followed by pupillary dynamics and accommodation response measurements using NeurOptics® pupillary light reflex™-3000 and Grand-Seiko WAM-5500 binocular accommodation auto ref/keratometer | shigiya machinery works LTD.

RESULTS:
A statistically significant difference was noticed for constriction percentage (%): 32.73 ± 9.20 versus 39.93 ± 7.36 (P < 0.001), average constriction velocity (mm/s): 2.24 ± 0.85 versus 2.62 ± 0.68 (P = 0.002), maximum constriction velocity (mm/s): 3.82 ± 1.33 versus 4.42 ± 0.93 (P = 0.004) and T75 (recovery period to 75% of the baseline pupillary diameter in sec): 1.38 ± 0.36 versus 2.0 ± 0.82 (P < 0.001) in mTBI compared to age-matched controls. A statistically significant difference was noted for accommodative response (in D) as well as in the sample as compared to age-matched controls: −1.12 ± 0.64 versus − 1.39 ± 0.47 (P < 0.001).

CONCLUSION:
Pupillary constriction velocities and accommodative response are significantly affected in mTBI. These findings have important clinical implications in being able to understand the visual symptoms following an mTBI.
Nonsurgical management of upper eyelid retraction in thyroid eye disease
Authors: Young Stephanie Ming , Kim Yoon-Duck , Woo Kyung In 
Published: May 2023

Abstract
Upper eyelid retraction (UER) is the most common sign of thyroid eye disease (TED) and may result in lagophthalmos and exposure keratopathy. Measures to address UER are varied and include conservative treatment, surgical intervention, and injections of botulinum toxin, hyaluronic acid (HA) filler, and triamcinolone acetonide (TA). Our article will discuss the various nonsurgical aspects of managing TED-related UER, focusing on the injections of botulinum toxin, HA filler, and TA to the upper eyelid, which have all been reported to be effective in improving UER in both active and inactive states of TED. Individual response may vary, and repeated injections may be necessary.
Kemampuan Shooting Futsal Ditinjau Dari Koordinasi Mata-Kaki dan Power Otot Tungkai
Authors: Anggita Ghina Putri Dana  , Nurhidayat Nurhidayat  , Andri Arif Kustiawan  
Published: May 2023

Penelitian ini dilakukan karena pencapaian prestasi yang signifikan oleh tim futsal SMK Negeri 2 Surakarta dalam beberapa kompetisi, terutama saat memenangkan kejuaraan di acara hari jadi di UMS pada tahun 2022. Namun, peneliti tidak mengetahui atau mengerti apakah penelitian ini ada suatu hubungan antara koordinasimata-kaki dan kekuatan otottungkai dengan kemampuan shooting pada anggota tim futsal tersebut. Oleh karena itu, penelitian ini mempunyai tujuan mengidentifikasi hubungan antara koordinasimata-kaki dan kekuatan otottungkai dengan kemampuan shooting pada anggota tim futsal ekstrakurikuler SMK Negeri 2 Surakarta. Penelitian futsal ini sendiri menggunakan sebuah metode deskriptiif dengan metode pendekatan kuantitatiff dserta desainn bentuk penelitian korelasional. Teknik sampel dalam penelitian ini yang digunakan adalah teknik purposivve shampling, di mana peneliti menetapkan kriteria tertentu untuk memilih sampel. Pengumpulan data dilakukan melalui tes dan pengukuran untuk mengumpulkan data koordinasi mata-kaki, kekuatan otot tungkai, dan kemampuan shooting futsal pada anggota tim futsal ekstrakurikuler SMK Negeri 2 Surakarta. Hasil analisiss ini menunjukkan bahwa ada suatu hubungan yang siggnifikan antara koordinasimata-kaki dan kekuatan otottungkai dengan kemampuan shooting futsal pada anggota tim futsal ekstrakurikuler SMK Negeri 2 Surakarta. Koefisien korelasi antara variabel-variabel tersebut sebesar 0,483 atau 48,3%. Berdasarkan hasil penelitian ini, bisa disimpulkan bahwasanya hipotesis yang menyatakan adanya kontribusi antara koordinasimata-kaki dan kekuatan otottungkai terhadap kemampuan shooting futsal pada anggota tim futsal ekstrakurikuler SMK Negeri 2 Surakarta diterima. Oleh sebab itu, H0 nya ditolak dan H1 nya diterima.
THE INFLUENCE OF LEADERSHIP STYLE AND COMPENSATION ON EMPLOYEESATISFACTIONAT PT. TETAP JAYA MEDAN
Authors: Manalu Eli Yanisa Boang , Sinaga Monica Novena , Simatupang Sabar L.T , Napitupulu R.B. 
Published: May 2023

Penelitian ini dilakukan pada PT Tetap Jaya Medan. Penelitian ini bertujuan untuk mengetahui Pengaruh Gaya Kepemimpinan terhadap Kepuasan Kerja Karyawan, Kompensasi berpengaruh terhadap Kepuasan Kerja Karyawan, serta Gaya Kepemimpinan dan Kompensasi berpengaruh terhadap Kepuasan Kerja Karyawan pada PT. Tetap Jaya Medan. Penelitian ini menggunakan pendekatan Kuantitatif. Yang menjadi Populasi pada penelitian ini adalah semua karyawan yang ada di PT Tetap Jaya Medan yaitu berjumlah 30 orang. Sampelnya ada sebanyak 30 responden. Metode analisis data yang digunakan adalah Uji Instrumen, Uji Asumsi Klasik, Uji Regresi Linier Berganda serta Uji Hipotesis dengan menggunakan SPSS Version 20 for Windows. Hasil Penelitian menunjukkan bahwa Gaya Kepemimpinan tidak berpengaruh terhadap Kepuasan Kerja Karyawan, Kompensasi berpengaruh terhadap Kepuasan Kerja Karyawan, serta Gaya Kepemimpinan dan Kompensasi berpengaruh secara simultan terhadap Kepuasan Kerja Karyawan. Hasil nilai Uji F dapat disimpulkan nilai signifikan (sig.) untuk pengaruh X1 dan X2 secara simultan (bersama-sama) terhadap Y adalah sebesar 0,001 < 0,05 dan nilai F hitung 8,987 > F tabel 3,35, sehingga demikian dapat disimpulkan bahwa terdapat pengaruh X1 dan X2 secara simultan (bersama-sama) terhadap Y. Hasil Uji Koefisien Determinasi menunjukkan bahwa pengaruh variabel Gaya Kepemimpinan dan Kompensasii secara simultann (bersama-sama) terhadap Kepuasan Kerja Karyawan adalahh sebesar 40%,