bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre- and postsynaptic nanostructures increase in size and complexity after LTP induction
Authors: Clavet-Fournier Valérie , Lee ChungKu , Wegner Waja , Brose Nils , Rhee JeongSeop , Willig Katrin I. 
Published: February 2023

AbstractSynapses, specialized contact sites between neurons, are the fundamental elements of neuronal information transfer. Synaptic plasticity is related to changes in synaptic morphology and the number of neurotransmitter receptors, and thought to underlie learning and memory. However, it is not clear how these structural and functional changes are connected. We utilized time-lapse super-resolution STED microscopy to visualize structural changes of the synaptic nano-organization of the postsynaptic scaffolding protein PSD95, the presynaptic scaffolding protein Bassoon, and the GluA2 subunit of AMPA receptors by chemically induced long-term potentiation (cLTP) at the level of single synapses. We found that the nano-organization of all three proteins undergoes an increase in complexity and size after cLTP induction. The increase was largely synchronous, peaking at ∼60 min after stimulation. Therefore, both the size and complexity of single pre- and post-synaptic nanostructures serve as substrates for adjusting and determining synaptic strength.Highlights- Time-lapse super-resolution images the structural changes of the PSD95 nano-organization after Cltp- cLTP-induced growth of the PSD95 nano-organization is less than spine head growth and peaks at 60 min, i.e. much slower than the increase in spine volume.- Most PSD95 nanostructures increase in complexity upon cLTP.- Synchronous growth - Nanostructures of pre- and postsynaptic scaffolding proteins and AMPA receptors increase simultaneously and equally strong upon cLTP.- GluA2-containing synaptic AMPA receptors form nanoclusters that increase in size and slightly in number upon cLTP and form subdomains on PSD95.- Bassoon forms complex structures similar to the PSD95 nano-organization.
Direct observation of a crescent-shape chromosome inBacillus subtilis
Authors: Tišma Miloš , Bock Florian Patrick , Kerssemakers Jacob , Japaridze Aleksandre , Gruber Stephan , Dekker Cees 
Published: February 2023

AbstractBacterial chromosomes are folded into tightly regulated three-dimensional structures to ensure proper transcription, replication, and segregation of the genomic information. Direct visualization of the chromosomal shape within bacterial cells is hampered by cell-wall confinement and the optical diffraction limit. Here, we combine cell-shape manipulation strategies, high-resolution fluorescence microscopy techniques, and genetic engineering to visualize the intrinsic shape of the bacterial chromosome in real-time in liveBacillus subtiliscells. We show that the chromosome exhibits a crescent shape with a non-uniform DNA density that is increased near the origin of replication (oriC). Additionally, we localized ParB and BsSMC proteins – the key drivers of chromosomal organization – along the contour of the crescent chromosome, showing the highest density nearoriC. Opening of the BsSMC ring complex disrupted the crescent chromosome shape and instead yielded a torus shape. These findings help to understand the threedimensional organization of the chromosome and the main protein complexes that underlie its structure.
Digital financial inclusion and economic growth in Sub-Saharan Africa: the role of institutions and governance
Authors: Chinoda Tough , Kapingura Forget Mingiri 
Published: February 2023

PurposeThis study examines the role of institutions and governance on the digital financial inclusion and economic growth nexus in Sub-Saharan Africa (SSA) from 2014 to 2020.Design/methodology/approachThis study adopts the generalised method of moments technique which controls for endogeneity. The authors employed four main variables namely, index of digital financial inclusion, gross domestic product per capita growth, institutions and governance.FindingsThe results suggest a significant positive effect of institutional quality and governance on the digital financial inclusion-economic growth nexus in SSA. Furthermore, the authors find that effect of trade and population growth on economic growth was significantly positive while inflation reduces economic growth in the region.Research limitations/implicationsThis study also ignored the effect of digital financial inclusion on environmental quality. Future researches should focus on addressing these drawbacks and replicating the study in Africa as a whole and other developing countries across the world that are experiencing digital financial inclusion and economic growth challenges. The results from the study imply that a positive relationship between digital financial inclusion and economic growth. It is important to note that the study was carried out on the premise that institutions play a pivotal role in enhancing economic growth in SSA.Practical implicationsThe results confirm the significance of policies that enhances institutional quality and governance which are other avenues the authorities can pursue to enhance economic growth in SSA.Social implicationsThe paper documents the importance of institutions in boosting economic growth which impacts on social life rather than digital financial inclusion only.Originality/valueThe paper makes a contribution through analysing the role of institutions and governance on the digital financial inclusion-economic growth nexus rather than the traditional financial inclusion–economic growth nexus which is common to the majority of the available empirical studies.
Political skills matter: the role of academic entrepreneurs in team innovation
Authors: Zhang Xueyan , Zhou Xiaohu , Wang Qiao , Wu Zhouyue , Sui Yue 
Published: February 2023

PurposeBased on social influence theory, this paper aims to explore the influence of academic entrepreneurs on team innovation activities. The innovation behavior of academic team members is the key behavior in academic entrepreneurial activities. As a special entrepreneurial group, academic entrepreneurs' political skills play an important role in stimulating team innovative behaviors.Design/methodology/approachThis paper adopts a multi-level study design and takes as samples the paired data of 91 academic entrepreneurial teams (n = 475). Based on team cognition, it constructs a model of the influence mechanism of academic entrepreneurs' political skills on team innovation behavior and explores the mechanism of transactive memory system in this influence effect. The authors use HLM and PROCESS macro to test our multilevel model.FindingsThe results show that academic entrepreneurs' political skills positively impact team innovation behavior, and a transactive memory system plays a mediating role between them. Team psychological safety significantly enhances the positive relationship of both academic entrepreneurs' political skills and a transactive memory system with team innovation behavior. Moreover, with enhanced perceptions of team psychological safety, academic entrepreneurs' political skills are more likely to improve team innovation behavior through the transactive memory system.Originality/valueThe study explores the influence of transactive memory system on the relationship between academic entrepreneurs' political skills and team innovation behavior, with the team cognitive perspective derived from social influence theory. This provides authors with new insights on the complex dynamics at place in the team innovation process and offers implications for how we can fruitfully manage this process.
Natural convection of NEPCM in a partial porous H-shaped cavity: ISPH simulation
Authors: Aly Abdelraheem M. , Alsedais Noura 
Published: February 2023

PurposeThis paper aims to investigate the conformable fractal approaches of unsteady natural convection in a partial layer porous H-shaped cavity suspended by nano-encapsulated phase change material (NEPCM) by the incompressible smoothed particle hydrodynamics method.Design/methodology/approachThe partial hot sources with variable height L_Hot are in the H-cavity’s sides and center. The performed numerical simulations are obtained at the variations of the following parameters: source of hot length L_Hot = (0.4–1.6), conformable fractal parameterα(0.97–1), fusion temperatureθf(0.05–0.9), thermal radiation parameterRd(0–7), Rayleigh numberRa(103–106), Darcy parameterDa(10−2to 10−5) and Hartmann numberHa(0–80).FindingsThe main outcomes showed the implication of hot source length L_Hot, Rayleigh number and fusion temperature in controlling the contours of a heat capacity within H-shaped cavity. The presence of a porous layer in the right zone of H-shaped cavity prevents the nanofluid flow within this area at lower Darcy parameter. An increment in the thermal radiation parameter declines the heat transfer and changes the heat capacity contours within H-shaped cavity. The velocity field is strongly enhanced by an augmentation on Rayleigh number. Increasing the Hartmann number shrinks the velocity field within H-shaped cavity.Originality/valueThe novelty of this work is solving the conformable fractal approaches of unsteady natural convection in a partial layer porous H-shaped cavity suspended by NEPCM.
Don't hate the players, hate the system! – The continuation of deep-rooted travel patterns in the face of shock events
Authors: Papp Bernadett , Neelis Ivar , Heslinga Jasper Hessel 
Published: February 2023

Purpose
It has been established that values, beliefs and norms are good predictors of pro-environmental behaviour; however, it is less explored how these constructs can be influenced. The purpose of this paper is to assess whether the COVID-19 pandemic, as a shock event, was a “game changer” or it had limited impacts on deep-rooted travel patterns.

Design/methodology/approach
To understand whether the pandemic has influenced people’s value orientations with regards to sustainable travel, the authors have made use of the value–belief–norm (VBN)theory of environmentalism and conducted a large-scale survey in Germany, Italy, France, The Netherlands and UK (N = 1545).

Findings
The findings showed that the pandemic caused only temporary change in deep-rooted travel patterns as (self-reported) pre-pandemic behaviour of respondents align with their value orientations and proved to be a good predictor of projected travel behaviour. Based on projected travel behaviour and value orientations, four market segments were identified – Frontrunners, Laggards, Comfortable Crowd and Entitled Stewards. While all segments showed willingness to adapt, the authors found variations in the extent of adaption and in the phases of the customer journey where travellers are likely to make changes.

Originality/value
According to our knowledge, using the VBN theory of environmentalism to understand the impact of shock events on deep-rooted travel patterns represents a new perspective. Moreover, to the best of authors’ knowledge, this study is one of the first, written in the midst of the COVID-19 pandemic, which looks at the impact of the health crisis on deep-rooted travel patterns, instead of the commonly studied risk perception.
The perspective of new managerialism on changes in Hong Kong's self-financing post-secondary education institutions: progress, challenges and outlook
Authors: Lau Yui-yip , Cheung Lok Ming Eric , Chan Eve Man Hin , Lee Stephanie Wing 
Published: February 2023

PurposeThe present study adopts the analytical framework of new managerialism (NM) to explore the progress, challenges and outlook of self-financing post-secondary institutions in Hong Kong since 2000. This study also identified issues and related managerial implications for developing this niche form of higher education in Hong Kong.Design/methodology/approachThis study conducted a critical review of self-financing post-secondary institutions in Hong Kong, including the sub-degree and degree sectors, via collecting a series of policy documents and archives from the Legislative Council of Hong Kong, the Public Records Office and other government bodies. To supplement the findings, semi-structured in-depth interviews of 18 academic staff of Hong Kong's self-financing post-secondary institutions were carried out.FindingsThe study shows that self-financing post-secondary institutions not only encounter challenges related to insufficient resources but also face pressure from accreditation requirements of various international organisations. The study also suggests that massification and privatisation of self-financing post-secondary institutions, and embracing a managerial approach for operation and governance will induce a new wave of self-financing post-secondary institutions in the near future.Originality/valueThis study offers insights for self-financing post-secondary institutions into implementing appropriate strategies to maintain competitiveness and retain talents in the coming years.
Going from 2D to 3D in supply chain 4.0 education: an LSP approach
Authors: Deif Ahmed 
Published: February 2023

PurposeThis study aims at investigating the impact of using Lego Serious Play (LSP) on the effectiveness of teaching supply chain (SC) 4.0 in higher education by going from a traditional 2D approach to a 3D one. LSP in this study is explored as a gamification pedagogical approach that taps into the connection between hands and brain to inspire and engage students to build 3D models using metaphors and storytelling.Design/methodology/approachAn empirical study was conducted among 50 students (over two terms) who were enrolled in a SC 4.0 course and used LSP in their final project that focused on digital SC design. Two questionnaires were designed (one after the standard LSP workshop and the other upon completion of the project) to solicit feedback with respect to how LSP helped students to better understand SC 4.0 topics and fulfill their project. The results were analyzed using Bloom’s taxonomy as well as other pedagogical framework to understand the positive impact of LSP at the cognitive, motivation and social levels.FindingsResults showed that using LSP can enhance the teaching of various SC principles and technologies beyond the abstract point of view (2D) through offering the students an opportunity to apply these principles and technologies in a futuristic project using a hands-on 3D approach. The LSP approach demonstrated its ability to help students navigate through both lower order thinking skills (LOTS) and higher order thinking skills (HOTS) in a meaningful and playful manner. Finally, improving the design skills for students was clear using LSP as it unleashes imagination and taps into internal knowledge together with collective inputs.Research limitations/implicationsThe reliance on one case study can be a limitation regarding the generalization of the proposed results. This limitation is attenuated by the representativeness of the case study analyzed. Furthermore, the presented work should encourage future analyses as well as expanding the implementation of LSP to other SC 4.0 teaching contexts and applications.Originality/valueThis paper contributes to the very few literatures regarding using gamification in SC education and specifically how LSP methodology can be adopted in teaching SCM 4.0.
Are environmental sustainability thoughts a panacea for environmental performance? Social innovation and moderating role of green innovation
Authors: Khattak Amira 
Published: February 2023

Purpose
This study aims to explore the association between environmental sustainability thoughts and environmental performance. Mediation through social innovation and moderating role of green innovation is also tested.

Design/methodology/approach
A quantitative research design was used for analyzing the personal/lived experience of 387 small–medium enterprises (SMEs) managers. Data were collected from persons who were performing their job, that is, it is based on current data. Cross-section data were collected through questionnaires. Correlation and regression analysis was used to test the study hypotheses.

Findings
Green innovation encourages firms to grow to be competent and increase their environmental performance. Results proved that businesses can work in a sustainable way through environmental sustainability thoughts and green innovation. Moreover, social innovation leveraged the interplay of environmental sustainability thoughts and the environmental performance.

Originality/value
The uniqueness of this research is that it combined environmental sustainability thoughts, social innovation and green innovation for developing environmental performance model for SMEs. This research includes new approach on sustainability domain and offered newest relevant factors to achieve a wider perceptive and multifaceted analysis of all dimensions that influence environmental performance.
The financial implications of XPS: an organizational learning perspective
Authors: Hekneby Torbjørn , Powell Daryl John 
Published: February 2023

Purpose
This study aims to investigate the impact of a company-specific lean program (a so-called company-specific production system [XPS]) on the company’s financial performance. This study analyzes data from the implementation of XPS in multiple plants of a multinational corporation and examines the results through an organizational learning lens.

Design/methodology/approach
This study adopts a longitudinal single-case design to investigate a Norwegian multinational company in the process industry, producing silicon for the global market. The company has developed, implemented and institutionalized its own XPS since 1991. The program has directly contributed to extensive cost reduction and significantly strengthened the organization’s competitive position.

Findings
The findings of this study show a link between organizational learning and the improvement of financial results in the organization. This study presents a sand cone model that illustrates how the development and deployment of an XPS through individual- and orchestrated learning subsequently created a common platform for institutionalized learning within and across the multinational organization. This organizational learning capability managed to tie the company’s continuous improvement efforts directly to the improvement of cost levels throughout the value chain.

Practical implications
The practical implications of this work are significant, as this study uncovers the importance for managers to consider both individual-, orchestrated- and institutionalized learning (within and across a multinational network) when designing and implementing XPS to drive the improvement of an organization’s financial performance.

Originality/value
Documenting the financial impact of such programs is a common challenge. Therefore, the insights presented in this research are of value to both researchers and practitioners, in particular, managers and executives in large multinational organizations.
Impact pathways: managing relational risk in project operations
Authors: Bryde David J. , Shahgholian Azar , Joby Roger , Taylor Simon , Singh Ruchi 
Published: February 2023

PurposeThe purpose of this paper is to assess how we implement new ways of managing relational risk at the operational level of outsourced projects and to provide guidance to project management (PM) policy makers and practitioners seeking to ensure project operations consistently deliver project relational risk management (PRRM) strategies.Design/methodology/approachThrough exploratory study data were obtained from a panel of six experts in PM and from a pilot survey of PM practitioners. The data reveal future directions and vectors for scholarship and research activity in terms of the impact of PRMM-related mechanisms and deliverables on project success and the implementation process to enhance PRRM as a key PM capability.FindingsDeliverables for PRRM need to part of a multidimensional framework that includes mechanisms besides the contract. Such a framework enables the codification of PM knowledge so that PRRM contributes to project success. With knowledge codified, PRRM strategies can be consistently delivered at the operational level. The framework is novel in that it integrates hereto disparate elements that are encompassed under the broad umbrella of relational governance mechanisms.Practical implicationsPM policy makers and practitioners recognise the importance of effective relationships to deliver projects successfully, yet they lack practical solutions to address the negative effects of dysfunctional relationships. The authors provide a list of PM deliverables for effective PRRM, including deliverables besides those related to the contract, which can be used in practice to bring the gap between PRRM strategy development and implementation. This will enable client organisations that outsource their projects to an external contractor to enhance their PRRM capability and increase the likelihood of project success.Originality/valueThe authors provide insights into how PRRM is practised at the project operations’ level where PM is outsourced. These insights lead to three pathways of impactful Operations Management (OM)/PM scholarship and research, namely, the following: 1) How PM deliverables act as a key success factor for effective PRRM? 2) How the duality of roles carried out by PM actors influences PRMM practices? 3) How companies innovate to enhance their PRMM capability? These pathways will enable PM research and scholarship to address disconnects between PRMM strategy and operations and hence go beyond answering “what” PRMM is to encompass “how” it is implemented.
The use of innovation uptake in identification of business models in the Indonesian smallholder cattle value chain
Authors: Asikin Zenal , Baker Derek , Villano Renato , Daryanto Arief 
Published: February 2023

PurposeThe purpose of this paper is to guide commercial and policy action to improve smallholder Indonesian cattle systems.Design/methodology/approachA survey (n = 304) of smallholder cattle farms in six villages in two districts of Nusa Tenggara Barat, Indonesia. Principal component analysis (PCA) and cluster analysis (CA) were employed to classify cattle farms into business models according to observed innovation. Differences between business models were identified using a one-way-analysis-of-variance (ANOVA).FindingsFour business models were identified, representing profiles of innovation adoption and elements of business models, socio-economic characteristics, farming system and performance variables including revenue, cost and profit. The business models display a range of orientation to buyer requirements and a range of approaches to production, indicating a need to promote in a variety of ways the change from supply-push to demand-pull in the cattle value chain.Research limitations/implicationsThis study offers guidance on how business models might be strengthened over time, by using simple indicators of performance and the models' linkage to innovation in the context of each business model. The business models developed here, and refinements to them based on localised conditions, offer a targeted and accelerated pathway to improved performance in smallholder systems.Originality/valueThis study proposed a novel approach to the recognition of business models based on innovation.