bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and One-Year Survival of Selected Major Congenital Anomalies in Germany: A Population-Based Cohort Study
Authors: Turial Salmai , Stimming Friederike , Lux Anke , Koehn Andrea , Rissmann Anke 
Published: December 2022

Abstract
Introduction Congenital anomalies play an important role in infant mortality worldwide. The present study aims to present the current data on the prevalence rates and the 1-year survival rates for selected major congenital anomalies in Saxony-Anhalt, Germany.
Materials and Methods The data were collected systematically by the Malformation Monitoring Centre Saxony-Anhalt. Cohort from 2000 to 2017 was retrospectively analyzed to determine the prevalence rates and the survival rates of nine major congenital anomalies. The survival analysis was conducted, including all pregnancy outcomes and various risk factors.
Results In total, 1,012 cases of the selected congenital anomalies were registered. The total prevalence rates ranged from 2.5 (congenital diaphragmatic hernia [CDH]) to 5.8 (spina bifida [SB]) per 10,000. The live birth prevalence was lower. In total, 88.3% of live-born cases survived the first year. The 1-year survival rate of all cases, including fetal losses, was merely 61.7%. There was no continual improvement in survival during the study period noted. The 1-year survival rate was 35.7% for “genetic” malformations, 57.6% for “multiple congenital anomalies,” and 68.6% for “isolated” cases, with 44.6% for prenatally detected anomalies and 85.2% for postnatally identified anomalies. Gestational age less than 31 weeks and birth weight below 1,000 g affected the survival rate adversely.
Conclusion The survival rate of infants suffering from congenital anomalies in Saxony-Anhalt is comparable to that reported by national and international studies. Registering all pregnancy outcomes irrespective of whether they result in a live birth, stillbirth, or fetal loss in a malformation register seems to be important as it affects the statistical survival analysis in general.
A Rare Charcot Neuro-Osteoarthropathy of Hip with an Uncommon Cause
Authors: Vijay Chandran , Geethapriya Sivaramalingam , Govindaraj Jayaraj , Raghavan Bagyam 
Published: December 2022

AbstractNeuro-osteoarthropathy often called as Charcot joint results from decreased sensory innervations of the involved joint resulting in severely damaged and disrupted joints and involvement of adjacent soft tissues. Charcot joint is characterized by the “6Ds,” which are i) distended joints, ii) density increase, iii) debris production, iv) dislocation, v) disorganization, and vi) destruction. Hip joint involvement is very rare probably because of rich nerve supply compared with other peripheral joints. To minimize the joint deformity and loss of function, early diagnosis is of great importance in which radiological imaging plays a major role.
Impact of the Community-Integrated Model of Samrakshan on Perinatal Mortality and Morbidity in Guna District of Central India
Authors: Sharma Lalit K. , Choorakuttil Rijo M. , Jadon Dhirendra Singh , Nirmalan Praveen K. 
Published: December 2022

AbstractAim The aim of this study was to assess the impact of the community-integrated Samrakshan model on perinatal mortality and morbidity in the Guna district of Central IndiaMethods The trimester-specific Samrakshan protocols were used to screen pregnant women in the first, second, and third trimesters of pregnancy and to stratify risk for preterm preeclampsia (PE) and fetal growth restriction (FGR) in the screened population. Low-dose aspirin was recommended for women identified at high risk in the first trimester screening. Fifty training programs were conducted over the duration of the program for district health workers including Anganwadi workers, Accredited Social Health Activist (ASHA) personnel, and women and child health staff. Data on the development of PE, stages of FGR, preterm births (PTBs), birthweight, neonatal mortality, and perinatal mortality were collected and compared with the baseline year to assess trends.Results The program covered 168 Anganwadi centers and screened 1,021 women in the first trimester, 870 women in the second trimester, and 811 women in the third trimester of pregnancy from 2019 to 2022 and obtained details on childbirth outcomes from 1,219 women. PE did not occur in 71.58% of pregnant women identified at high risk for PE and occurred in only 2.37% of pregnant women identified at low risk for PE. The incidence of PE reduced from 9.36 to 1.61%, stage 1 FGR from 18.71 to 11.83%, PTB from 19.49 to 11.25%, and birthweight less than 2,500 g from 33.66 to 21.46% from 2019 to 2022. The neonatal mortality rate reduced from 26 to 7.47/1,000 live births from 2019 to 2022 and the perinatal mortality rate reduced from 33.90 to 18.87/1,000 childbirths from 2019 to 2022 in the Samrakshan program area at Guna.Conclusion The community-integrated model of Samrakshan in the Guna district has led to a significant reduction in perinatal morbidity and mortality in the program area.
A Comparison of Postoperative Pain and Narcotic Prescriptions in Patients Undergoing Total Hip Arthroplasty Electively or for Femoral Neck Fracture
Authors: Fisher Nina D. , Oakley Christian , Arraut Jerry , Rozell Joshua C. , Egol Kenneth A. , Schwarzkopf Ran 
Published: December 2022

AbstractThe opioid epidemic has forced orthopaedic surgeons to reevaluate prescribing patterns and led hospitals to develop postoperative opioid-sparing protocols for patients undergoing total hip arthroplasty (THA). The purpose of this study was to investigate patient-reported pain and narcotic requirements in patients undergoing THA for fracture (F-THA) or nonfracture diagnoses (THA-E). A retrospective analysis was performed on patients who underwent primary THA at a single academic institution between January 2013 and December 2020. Patients with postoperative opioid prescription and Visual Analog Scale (VAS) pain score data were included. Patients who underwent primary THA with a diagnosis of femoral neck fracture (THA-F) were matched 1:1 with patients without primary fracture diagnoses (THA-E) using nearest-neighbor propensity-score matching. Operative time, length of stay (LOS), discharge disposition, 90-day readmission rates, 90-day opioid prescription amounts (quantified by morphine milligram equivalents [MME]), and daily postoperative VAS pain scores (averaged over 24-hour periods) were compared. A total of 8,714 patients met inclusion criteria (THA-E: 8,362; THA-F: 352). The THA-F group was older and had a higher proportion of females and a lower mean body mass index than the THA-E group. There were 331 THA-F patients successfully matched to 331 THA-E patients. Operative time (113.6 ± 41.3 vs. 914.9 ± 32.6 minutes, p < 0.001) and LOS (2.90 ± 2.82 vs. 2.32 ± 1.44 days, p < 0.001) were longer in fracture patients. The THA-F demonstrated equivalent pain scores at 0 to 24 and 48 to 72 hours postoperatively but had slightly higher pain scores at 24 to 48 hours postoperatively (4.04 ± 1.67 vs. 3.71 ± 1.65, p = 0.028). Ninety-day opioid prescriptions were higher in the THA-E group (median [interquartile range], 150.0 [93.3–300.0] vs. 100.0 [40.0–200.0] MME, p = 0.034). In multivariate regression, a diagnosis of fracture was not associated with changes in MME administration. Patients undergoing primary THA electively and for femoral neck fractures can expect similar postoperative pain scores, though fracture patients may require less narcotics postoperatively. All patients should continue to be counseled preoperatively on the dangers and side effects of prolonged opioid use.
Catastrophic Antiphospholipid Syndrome: A Case Series
Authors: Christopher Navya , Periaswamy Gopinath , Arunachalam Venkatesh Kasi , Mangalakumar V. , Mehta Pankaj , Cherian Mathew 
Published: December 2022

AbstractCatastrophic antiphospholipid syndrome (CAPS) is the rare but most severe form of antiphospholipid syndrome with multiple organ ischemia developing over a short period of time. CAPS should be considered when imaging suggests an acute and concurrent multiorgan ischemia, associated with positive antiphospholipid antibodies. As CAPS can have fulminant irreversible complications, its early recognition is important to initiate the treatment promptly. We present three patients of CAPS who were managed at our institution.
Association between Neonatal Abstinence Syndrome and Congenital Anomalies in the United States
Authors: Bhatt Parth , Ampem-Darko Cecilia , Cudjoe Grace Annan , Parmar Narendrasinh , Oredein Igbagbosanmi , Asiama Adwoa O. , Patel Jenil , Pemmasani Sahithi , Linga Vijay Gandhi , Donda Keyur , Doshi Harshit , Dapaah-Siakwan Fredrick 
Published: December 2022

Objective Studies exploring the relationship between neonatal abstinence syndrome (NAS) and congenital anomalies (CA) in the United States are limited given the small sample size or data prior to the opioid epidemic. We aimed to determine if there is an association between NAS and CA in a nationally representative cohort of newborn hospitalization in the United States.
Study Design This was a cross-sectional analysis of NAS-related hospitalizations within the 2016 Kids Inpatient Database. International Classification of Diseases (ICD-10-CM) diagnostic codes were used to identify NAS hospitalizations and those with and without CA. The primary outcome was the odds of CAs in NAS hospitalizations. Multivariate survey logistic regression was used to analyze the relationship between NAS and CA.
Results Among 3.7 million newborn hospitalizations, 25,394 had NAS (6.7 per 1,000). The prevalence of any CA was higher in those with NAS when compared with non-NAS hospitalizations (10.3 vs. 4.9%; odds ratio = 2.27; 95% confidence interval [CI]: 2.13–2.43). Adjusted analysis showed similar results (adjusted odds ratio: = 1.83, CI: 1.71–1.95). NAS hospitalizations with CA had a higher mortality rate (0.6 vs 0.04%, p < 0.0001) and higher resource use.
Conclusion This nationwide study shows that NAS may be associated with increased odds of CAs, suggesting that NAS may be a risk factor for increased morbidity in the newborn period.
Key points
Unplanned Extubations in Pediatric Critical Care: A Case–Control Study
Authors: Wollny Krista , Williams Cameron B. , Al-Abdwani Raghad , Cartelle Carol , Macartney Jason , Frndova Helena , Chin Norbert , Parshuram Christopher 
Published: December 2022

AbstractThe aim of this study was to quantify associations between the risk of unplanned extubation and patient-, environment-, and care-related factors in pediatric critical care and to compare outcomes between children who did and did not experience an unplanned extubation. This is a retrospective case–control analysis including patients <18 years who experienced an unplanned extubation during intensive care unit (ICU) admission (2004–2014). Cases were matched by age, duration of mechanical ventilation, and date to control patients (4:1) who were intubated but did not experience an unplanned extubation. Conditional logistic regression was used to evaluate associations between unplanned extubations and the abstracted characteristics. We identified 1,601 eligible controls matched to 458 case patients. When adjusted for confounders, eight variables were associated with unplanned extubation: three patient-related factors (previous ICU admission, previous intubation, and the volume of secretions); one environment-related factor (patient room setup); and four care-related factors (intubation route, and the use of sedation, muscle relaxation, and restraints). Patients who had an unplanned extubation had longer length of stay, but lower rate of mortality. This is the largest case–control study identifying variables associated with unplanned extubation in pediatric critical care. Several are potentially modifiable and may provide opportunities to improve quality of care in controlled ICU environments.
A plant-unique protein BLISTER coordinates with core retromer to modulate endosomal sorting of plasma membrane and vacuolar proteins
Authors: Li Hongbo , Huang Ruihua , Liao Yanglan , Yang Shuhong , Feng Bojin , Qin Hongting , Zhou Jun , Zeng Yonglun , Shen Jinbo , Zhuang Xiaohong , Jiang Liwen , Otegui Marisa S. , Zhang Shengchun , Gao Caiji 
Published: December 2022

The retromer is a heteromeric protein complex that localizes to endosomal membranes and drives the formation of endosomal tubules that recycle membrane protein cargoes. In plants, the retromer plays essential and canonical functions in regulating the transport of vacuolar storage proteins and the recycle of endocytosed plasma membrane proteins (PM); however, the mechanisms underlying the regulation of assembly, protein stability, and membrane recruitment of the plant retromer complex remain to be elucidated. In this study, we identify a plant-unique endosomal regulator termed BLISTER (BLI), which colocalizes and associates with the retromer complex by interacting with the retromer core subunits VPS35 and VPS29. Depletion of BLI perturbs the assembly and membrane recruitment of the retromer core VPS26-VPS35-VPS29 trimer. Consequently, depletion of BLI disrupts retromer-regulated endosomal trafficking function, including transport of soluble vacuolar proteins and recycling of endocytosed PIN-FORMED (PIN) proteins from the endosomes back to the PM. Moreover, genetic analysis inArabidopsis thalianamutants reveals BLI and core retromer interact genetically in the regulation of endosomal trafficking. Taken together, we identified BLI as a plant-specific endosomal regulator, which functions in retromer pathway to modulate the recycling of endocytosed PM proteins and the trafficking of soluble vacuolar cargoes.
Bias field orientation driven reconfigurable magnonics and magnon−magnon coupling in triangular shaped Ni80Fe20 nanodot arrays
Authors: Kumar Mondal Amrit , Majumder Sudip , Kumar Mahato Bipul , Barman Saswati , Otani Yoshichika , Barman Anjan 
Published: December 2022

Abstract
Reconfigurable magnonics have attracted intense interest due to their myriad advantages including energy efficiency, easy tunability and miniaturization of on-chip data communication and processing devices. Here, we demonstrate efficient reconfigurability of spin-wave (SW) dynamics as well as SW avoided crossing by varying bias magnetic field orientation in triangular shaped Ni80Fe20 nanodot arrays. In particular, for a range of in-plane angles of bias field, we achieve mutual coherence between two lower frequency modes leading to a drastic modification in the ferromagnetic resonance frequency. Significant modification in magnetic stray field distribution is observed at the avoided crossing regime due to anisotropic dipolar interaction between two neighbouring dots. Furthermore, using micromagnetic simulations we demonstrate that the hybrid SW modes propagate longer through an array as opposed to the non-interacting modes present in this system, indicating the possibility of coherent energy transfer of hybrid magnon modes. This result paves the way for the development of integrated on-chip magnonic devices operating in the gigahertz frequency regime.
Shape dynamics of N point vortices on the sphere
Authors: Ohsawa Tomoki 
Published: December 2022

Abstract
We give a geometric account of the relative motion or the shape dynamics of N point vortices on the sphere exploiting the

S
O

(
3
)

-symmetry of the system. The main idea is to bypass the technical difficulty of the

S
O

(
3
)

-reduction by first lifting the dynamics from

S

2

to

C

2

. We then perform the

U

(
2
)

-reduction using a dual pair to obtain a Lie–Poisson dynamics for the shape dynamics. This Lie–Poisson structure helps us find a family of Casimirs for the shape dynamics. We further reduce the system by

T

N
−
1

-symmetry to obtain a Poisson structure for the shape dynamics involving fewer shape variables than those of the previous work by Borisov and Pavlov. As an application of the shape dynamics, we prove that the tetrahedron relative equilibria are stable when all of their circulations have the same sign, generalizing some existing results on tetrahedron relative equilibria of identical vortices.
Novel orthorhombic silicane nanosheet as a sensing material for acrolein and propanol—a first-principles investigation
Authors: Nagarajan V , Chandiramouli R 
Published: December 2022

Abstract
Currently, the elemental monolayer materials attracted great interest among the research communities due to their stability, selectivity, and sensitivity towards hazardous vapour or gas molecules. In this research work, we deployed an orthorhombic silicane nanosheet (Ortho-SiNS) as a sensing element to detect acrolein and propanol at ambient conditions. Initially, the structural firmness of Ortho-SiNS is verified with the support of formation energy. Subsequently, the electronic features of the base substrate are discussed using band structure along with projected density of states maps. The estimated energy gap of Ortho-SiNS is found to be 4.179 eV. The interaction behaviour of target air pollutants on Ortho-SiNS is investigated by ascertaining Bader charge transfer, relative band gap changes, and adsorption energy. In the present work, the adsorption energy is calculated in the scope of −0.305 eV to −1.039 eV, which validates the physisorption of acrolein and propanol on Ortho-SiNS. The outcomes recommended that the Ortho-SiNS can be employed as a promising chemical sensor to sense acrolein and propanol molecules from cigarette smoke.
Transmission dynamics of monkeypox virus with treatment and vaccination controls: a fractional order mathematical approach
Authors: Majee Suvankar , Jana Soovoojeet , Barman Snehasis , Kar T K 
Published: December 2022

Abstract
Presently, monkeypox virus infection has spread worldwide in the ongoing outbreak that began in the UK. To study the transmission dynamics of monkeypox, we formulate here a seven-compartmental (five compartments for the human population and two compartments for animals or rodents) fractional-order mathematical model. The existence and uniqueness of the solution of the proposed fractional order model are examined here. The basic reproduction number for humans (

R

0

h

) and animals (

R

0

a

) are obtained through the next-generation matrix approach. Depending on the values of

R

0

h

and

R

0

a

, we observed that the fractional order model has three equilibria, namely, monkeypox-free equilibrium, animal-free endemic equilibrium, and endemic equilibrium. Also, the stability of all equilibria is checked in this present article. We found that the model goes through transcritical bifurcation at

R

0

a

=
1

for any values of

R

0

h

and at

R

0

h

=
1

for

R

0

a

<
1

. Best of our knowledge, this is the first work where the fractional order optimal control for monkeypox is formulated and solved considering vaccination and treatment controls. Several feasible parameter values are used in the simulations to visualize and verify the findings, from which the results show that fractional order is more appropriate. Finally, parameters involved in the expression of

R

0

h

and

R

0

a

are scaled using the sensitivity index approach.
Manipulating mid-infrared wavefront through reflective Ge3Sb2Te6 metasurfaces
Authors: Du Zhiqiang , Song Zhengyong 
Published: December 2022

Abstract
Due to the increasing complexity of modern communication systems, the requirements for electromagnetic wave are becoming more and more rigorous. Traditional natural materials are not easy to integrate into tunable systems. Metasurface is a two-dimensional array, and it has a more significant advantage in electromagnetic control and attracts great attention. Here, Ge3Sb2Te6-based metasurfaces are presented to control electromagnetic wavefront by changing the state of Ge3Sb2Te6 in the mid-infrared range. Eight meta-atoms are designed to form linear phase distribution with phase difference of 45° at 74 THz. When Ge3Sb2Te6 is in the amorphous state, the designed meta-atoms have low loss and high reflection. Ge3Sb2Te6 block is designed into a specific structure in a certain way, which realizes deflection of electromagnetic wavefront and vortex beam with orbital angular momentum l = 1 or l = 2. By means of convolution, anomalous reflection is combined with orbital angular momentum to form an anomalously deflected vortex beam. When the state of Ge3Sb2Te6 is crystalline, amplitudes of meta-atoms decrease and linear phase distribution is destroyed. Reflected wave becomes almost mirror reflection wave. Our design may open a pathway to novel types of metasurfaces.
A Note on the Anti-glitch of Magnetar SGR 1935+2154
Authors: Tong H. 
Published: December 2022

Abstract
The magnetar SGR 1935+2154 is reported to have an anti-glitch, accompanied by fast radio bursts, and transient pulsed radio emission. In the wind braking model, this triplet event tells people that (1) SGR 1935+2154 does not have a strong particle wind and can be approximated by magnetic dipole braking in the persistent state; (2) its anti-glitch is due to an enhanced particle wind, similar to the first anti-glitch in magnetars; (3) its transient pulsed radio emission may be due to a decreasing emission beam during the outburst; (4) the enhanced particle acceleration potential and pulsar death line may not be the dominate factor.
ARAS Algorithm as Decision Support System’s Technique for Selection Student Creativity Program
Authors: Abbas Aries , Masri Debi , Prayitno Pungkas , Hasanuddin H , Zaenuddin Z , Yuridka Fitrah , Raharjo Mokhamad Ramdhani , Anwar Yohny 
Published: December 2022

Abstract
Indonesia’s Directorate General of Higher Education, Ministry of Research, Technology, and Higher Education founded the Student Creativity Program (abbreviated as PKM) to help Indonesian students better understand, develop, and apply the science and technology they learn in class. Public and private university students alike can participate in this important event. Once a proposal has been submitted and reviewed at each institution, the activity moves on to the national level. Students at colleges and universities have the power to select the best proposals to ensure that the best ideas get funded. The choice is made by the research and community service institution (abbreviated as LPPM). LPPM uses qualified reviewers in their respective fields to do the selection. After that, the papers are ranked according to the PKM guidebook’s evaluation components, which are listed in the review findings. A comparison method is essential to evaluate proposals because subjective evaluation is severely discouraged. PKM proposal selection will be examined utilizing decision support system methodologies in this study. The problem was solved using the Additive Ratio Assessment (ARAS) approach. Title, Abstract, Preliminary; Destination; Method; Discussion Result; Conclusion; and Bibliography comprise the eight components of the assessment criteria based on 21 samples of PKM proposals. The ARAS technique calculates that nine suggestions are deserving of national selection, with a Ki value ranging from 0.97534518 to 0.70813085.
Implementation Learning Vector Quantization Using Neural Network for Classification of Ear, Nose and Throat Disease
Authors: Samsir Samsir , Daulay Nelly Khairani , Harahap Syaiful Zuhri , Zalmi Wahyuni Fithratul , Sari Afni Nia , Nasution Fitri Aini , Watrianthos Ronal 
Published: December 2022

Abstract
This study aims to use data from 57 patients at Rantauprapat Hospital to train a Neural Network using a quantization learning vector method for the categorization of ear, nose, and throat disorders. The input factors were fever, tiredness, nausea, breathing pain, sore throat, hearing loss, allergies, chills and sweating, and thick and transparent mucus. The factors studied were ear canal infections, pharyngitis of the neck, throat, nose, and sinusitis. The findings revealed that ten neurons with an objective value of 0.01 in the learning rate range of 0.01 - 0.05 resulted in categorizing snoring, nose, and ear disorders, including the input layer. The MATLAB program is utilized in this approach, with an average accuracy of 67 per cent and a mean square error of 0.2.