bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pratiques philosophiques et éducation relative à l'environnement : interroger les conditions d’un rapprochement
Authors: Bérard Marion , Coasne-Khawrin Marie , Delanoë Agathe , Dufourt Pénélope 
Published: January 2025

Le projet de mobiliser les pratiques philosophiques pour l’éducation relative à l’environnement (ERE), loin d’être évident, soulève plusieurs questions. Les pratiques philosophiques sont-elles réellement adaptées aux objectifs de l’ERE et notamment, à l’urgence de l’action, étant donné leur dimension intellectuelle ? Poursuivre un objectif d’ERE ne risque-t-il pas de mener à une instrumentalisation des pratiques philosophiques ? La pratique du dialogue philosophique telle qu’initiée par Matthew Lipman et Ann Margaret Sharp nous semble fournir des réponses à ces questions en ce qu’elle propose des ressources précieuses pour l’ERE : elle est à même de prendre en charge les questions épistémologiques, existentielles et éthiques liées à ces questions socialement vives, en les pensant de manière critique, attentive et réfléchie et en rendant justice à leur dimension d’incertitude. Toutefois, des tensions possibles relatives à un tel rapprochement demeurent eu égard aux institutions dans lesquelles ces pratiques éducatives pourraient avoir lieu.
Clinician’s guide to the management of azoospermia induced by exogenous testosterone or anabolic–androgenic steroids
Authors: Al Hashimi Manaf , Pinggera Germar-Michael , Shah Rupin , Agarwal Ashok 
Published: January 2025

Abstract
Azoospermia, defined as the absence of sperm in the ejaculate, is a well-documented consequence of exogenous testosterone (ET) and anabolic–androgenic steroid (AAS) use. These agents suppress the hypothalamic–pituitary–gonadal (HPG) axis, leading to reduced intratesticular testosterone levels and impaired spermatogenesis. This review examines the pathophysiological mechanisms underlying azoospermia and outlines therapeutic strategies for recovery. Azoospermia is categorized into pretesticular, testicular, and post-testicular types, with a focus on personalized treatment approaches based on the degree of HPG axis suppression and baseline testicular function. Key strategies include discontinuing ET and monitoring for spontaneous recovery, particularly in patients with shorter durations of ET use. For cases of persistent azoospermia, gonadotropins (human chorionic gonadotropin [hCG] and follicle-stimulating hormone [FSH]) and selective estrogen receptor modulators (SERMs), such as clomiphene citrate, are recommended, either alone or in combination. The global increase in exogenous testosterone use, including testosterone replacement therapy and AAS, underscores the need for improved management of associated azoospermia, which can be temporary or permanent depending on individual factors and the type of testosterone used. Additionally, the manuscript discusses preventive strategies, such as transitioning to short-acting testosterone formulations or incorporating low-dose hCG to preserve fertility during ET therapy. While guidelines for managing testosterone-related azoospermia remain limited, emerging research indicates the potential efficacy of hormonal stimulation therapies. However, there is a notable lack of well-structured, controlled, and long-term studies addressing the management of azoospermia related to exogenous testosterone use, highlighting the need for such studies to inform evidence-based recommendations.
Awareness of prostate cancer and its screening tests in men in the Middle East: A systematic review and meta-analysis
Authors: Mohamed Nawaf S.A. , Asfari Joud M.O. , Sambawa Samar M.A. , Aljurf Rima M.D. , Alsaygh Kholoud A.A. , Arafah Assad M. 
Published: January 2025

Abstract:
Prostate cancer (PCa) is a significant health issue characterized by the uncontrolled growth of cells in the prostate gland primarily affecting men 50 years old or older. The aim of this research was to assess the level of knowledge and attitudes of men in the Middle East towards PCa. A comprehensive search strategy in major databases from the date of first publication on this topic to April 2024 was conducted of cross-sectional studies assessing the knowledge and attitudes of adult men in the Middle East toward PCa. Data on the study’s methodology, participant characteristics, and outcomes related to the knowledge of PCa and attitudes towards PCa were extracted and analyzed using the comprehensive meta-analysis software. The Newcastle–Ottawa Scale was used for quality assessment. The meta-analysis of 26 studies revealed significant heterogeneity among studies, with an overall rate of previous education on PCa at 76.3% (95% confidence interval [CI]: 61.2%– 86.8%), but a much lower rate of education on PCa screening at 20.5% (95% CI: 7.2%–46.2%). Knowledge of PCa, its screening tools, symptoms, risk factors, and treatments, as well as attitudes towards PCa screening, varied widely, with knowledge rates of 50.5% for PCa, 32.3% for screening tools, 45.5% for symptoms, 49.4% for risk factors, and 58.4% for treatments. The rate of favorable attitude towards PCa screening was reported at 50.0% (95% CI: 36.7%–63.3%). The Middle East has some understanding of PCa but there is little knowledge of screening techniques, symptoms, risk factors, and treatments. To improve early detection and patient outcomes, comprehensive education and culturally sensitive communication strategies are necessary.
Voltage-dependent anion channel 1 oligomerization regulates PANoptosis in retinal ischemia–reperfusion injury
Authors: Wan Hao , Ban Xiaoxia , He Ye , Yang Yandi , Hu Ximin , Shang Lei , Wan Xinxing , Zhang Qi , Xiong Kun 
Published: January 2025

Abstract
Ischemia-reperfusion injury is a common pathophysiological mechanism in retinal degeneration. PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis, apoptosis, and necroptosis. Oligomerization of mitochondrial voltage-dependent anion channel 1 is an important pathological event in regulating cell death in retinal ischemia-reperfusion injury. However, its role in PANoptosis remains largely unknown. In this study, we demonstrated that voltage-dependent anion channel 1 oligomerization-mediated mitochondrial dysfunction was associated with PANoptosis in retinal ischemia-reperfusion injury. Inhibition of voltage-dependent anion channel 1 oligomerization suppressed mitochondrial dysfunction and PANoptosis in retinal cells subjected to ischemia-reperfusion injury. Mechanistically, mitochondria-derived reactive oxygen species played a central role in the voltage-dependent anion channel 1-mediated regulation of PANoptosis by promoting PANoptosome assembly. Moreover, inhibiting voltage-dependent anion channel 1 oligomerization protected against PANoptosis in the retinas of rats subjected to ischemia-reperfusion injury. Overall, our findings reveal the critical role of voltage-dependent anion channel 1 oligomerization in regulating PANoptosis in retinal ischemia-reperfusion injury, highlighting voltage-dependent anion channel 1 as a promising therapeutic target.
Bone marrow mesenchymal stem cells promote uterine healing by activating the PI3K/AKT pathway and modulating inflammation in rat models
Authors: Yang Jing , Yuan Jun , Wen Yan-Qing , Wu Li , Liao Jiu-Jiang , Qi Hong-Bo 
Published: January 2025

BACKGROUND
Uterine injury can cause uterine scarring, leading to a series of complications that threaten women’s health. Uterine healing is a complex process, and there are currently no effective treatments. Although our previous studies have shown that bone marrow mesenchymal stem cells (BMSCs) promote uterine damage repair, the underlying mechanisms remain unclear. However, exploring the specific regulatory roles of BMSCs in uterine injury treatment is crucial for further understanding their functions and enhancing therapeutic efficacy.
AIM
To investigate the underlying mechanism by which BMSCs promote the process of uterine healing.
METHODS
In in vivo experiments, we established a model of full-thickness uterine injury and injected BMSCs into the uterine wound. Transcriptome sequencing was performed to determine the enrichment of differentially expressed genes at the wound site. In in vitro experiments, we isolated rat uterine smooth muscle cells (USMCs) and cocultured them with BMSCs to observe the interaction between BMSCs and USMCs in the microenvironment.
RESULTS
We found that the differentially expressed genes were mainly related to cell growth, tissue repair, and angiogenesis, while the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway was highly enriched. Quantitative reverse-transcription polymerase chain reaction was used to validate differentially expressed genes, and the results demonstrated that BMSCs can upregulate genes related to regeneration and downregulate genes related to inflammation. Coculturing BMSCs promoted the migration and proliferation of USMCs, and the USMC microenvironment promoted the myogenic differentiation of BMSCs. Finally, we validated the PI3K/AKT pathway in tissues and cells and showed that BMSCs activate the PI3K/AKT pathway to promote the regeneration of uterine smooth muscle both in vivo and in vitro .
CONCLUSION
BMSCs upregulated uterine wound regeneration and anti-inflammatory factors and enhanced uterine smooth muscle proliferation through the PI3K/AKT pathway both in vivo and in vitro .
Formalización y la evasión tributaria en la ciudad de Lima Metropolitana, 2023
Authors: Cruz Conde Daniel 
Published: January 2025

The purpose of this research was to determine the relationship between formalization and tax evasion in the city of Metropolitan Lima, 2022. The study was situated within the framework of the mixed approach, which is an approach that integrates both quantitative and qualitative methods in order to obtain a more holistic perspective of the phenomena studied. The present research was explanatory in nature since it serves as a basis for research and formulates hypotheses. The research design was non-experimental, since a series of symbols were used that have a denotation that is important to know in order to read them comprehensively. The population was 1,000 businessmen in the city of Metropolitan Lima and the sample was 278 businessmen. In conclusion, a significant relationship was identified between formalization and tax evasion in the city of Metropolitan Lima, 2023. This finding is supported by the Spearman correlation coefficient, which reached a value of 0.415, and the bilateral sigma of 0.000. These results suggest that formalization plays an important role in tax evasion in this specific context.
Distance of flight of cosmic-ray muons to study dynamics of the upper muosphere
Authors: Tanaka Hiroyuki K. M. 
Published: January 2025

Abstract. The Earth can be divided by main layers, including the atmosphere, geosphere (solid Earth), and biosphere, depending on its predominant component. In this work, the layer of the Earth which constantly contains a high concentration of muons (∼8×1012 muons) and its upper border are respectively defined as the muosphere and muopause. The altitude of the muosphere spans from the lower stratosphere to the upper crust of the Earth. In order to study its dynamics, the muopause height was spatiotemporally studied with a new kind of technique called the distance of flight (DOF), which utilizes variations in the muon's decay length. In this work, (A) numerical modeling was performed, and it was clarified that seasonal variations in the cosmic muon flux are predominantly ruled by muopause dynamics; (B) the muon data were compared with the balloon-based measurement results, and it was confirmed that muopause dynamics are closely related to lower-stratospheric height variations. Since the muopause is the region spanning the area between the upper troposphere and the lower stratosphere, the potential of the current distant of flight (DOF) approach needs to be further investigated by cross-comparing related case studies and other atmospheric climate datasets.
Imaginario visual de los derechos humanos e iconografías digitales
Authors: Martorell Sandra , Lopezosa Carlos , Codina Lluís 
Published: January 2025

Los derechos humanos fueron proclamados en 1948. Desde entonces se ha ido forjando un imaginario colectivo en torno a este concepto que ha ido calando en la sociedad a través, entre otro, de las imágenes que los representan. Esta investigación tiene por objetivos conocer, por un lado, si existe correlación entre las imágenes que conforman el imaginario visual y las que nos ofrece Google Images, como motor de búsqueda hegemónico. Por otro, analizar dichas imágenes, con el fin de ver cómo se representa la idea que tenemos de los derechos humanos en la contemporaneidad y de qué forma las iconografías digitales están contribuyendo a seguir alimentando dicho imaginario. Para ello, se combinaron dos metodologías de trabajo: la semana construida (Riffe, 1993) y el diseño de un cuestionario abierto con opción mixta de respuesta (textual o gráfica) aplicado a un grupo de personas. El estudio concluye que: (1) cuando hablamos de derechos humanos en abstracto y de forma general, obtenemos imágenes mayoritariamente simbólicas y de carácter gráfico, con una connotación positiva y esperanzadora. (2) Cuando concretamos, las imágenes que obtenemos ya no muestran ideales de futuro, sino que son imágenes fotográficas, que nos muestran una realidad más cruda y nos recuerdan que aún queda mucho por hacer en materia de derechos humanos.
Expansion of the buffalo agri-system and industry following the One Health approach
Authors: Carruyo Gabriela M. , Calderon Ericka , Hoet Armando E. 
Published: January 2025

One Health approach is looking for conceiving health as a consequence of interaction in the interphase of the human/animal/environment complex as an interlinked whole, targeting to change how human beings have traditionally managed health. Lessons learned with the recent Covid 19 pandemic and the silent pandemic of antimicrobial resistance (AMR), among others known as potential pandemics, have put on top the need to change how to tackle health threats. The world is constantly challenged by zoonotic diseases, the emergence of new diseases promoted by human ecosystem invasion, climate change, loss of biodiversity, and the inability of nature to restore exhausted ecosystems due to human activity. The increasing world population demands sufficient, safe, and nutritious food, but food production also needs good practices and fair trade. Otherwise, food can become an essential source of illness, disseminating pathogens and AMR, leading to an unsustainable economy. Links between food and health are currently well recognized. Risk assessment and traceability during food production and distribution are crucial to ensure food safety, security, and sustainability. As growing food producers and suppliers, Buffalo Agri-systems and industry have the opportunity to positively impact the development of sustainable economic systems. Expansion of buffalo Agri-systems and industry will require to be in line with the six areas of action of the One Health Joint Plan of Action 2022-2026 (OH JPA) through incorporation of good production practices, decreasing ecosystem negative impact and processing and distribution of safe food in agreement with national and international standards and guidelines.
Stenotic Intercondylar Notch as a Risk Factor for Physeal-Sparing ACL Reconstruction Failure: A Case-Control Study
Authors: Tuca María , Gausden Elizabeth , Luderowski Eva , Valderrama Ignacio , Potter Hollis , Cordasco Frank , Green Daniel 
Published: January 2025

Introduction:
Identifying risk factors is crucial for developing strategies that minimize reinjury after anterior cruciate ligament reconstruction (ACLR). This study aims to determine whether certain features of intercondylar notch geometry are associated with failure of physeal-sparing ACLRs in skeletally immature athletes.

Methods:
Nine failed physeal-sparing ACLRs were compared with a control subject group of 15 age- and sex-matched intact physeal-sparing ACLRs. Notch width index (NWI), notch angle (NA), and intercondylar notch roof inclination angle (RA) were measured on preoperative MRIs.

Results:
Median NWI was smaller in the failed ACLR versus control subject group in coronal (0.23 versus 0.27; P < 0.05) and axial planes (0.25 versus 0.27; P = 0.055). Median NA was smaller in the failed ACLR versus control subject group in coronal (49.6 versus 61.0°; P < 0.05) and axial planes (48.6° versus 54.9°; P < 0.05). Median RA was steeper in the failed ACLR versus control subject group (132.0° versus 125.7°; P < 0.05).

Conclusion:
NWI, NA, and RA were associated with ACLR failure in skeletally immature patients undergoing physeal-sparing reconstruction. A smaller, narrower, and steeper notch may predispose these patients to reinjury.

Level of Evidence:
Level III, retrospective comparative study.
IOT Based Air Pollution Detection and Monitoring Using Arduino
Authors:   Assistant Professor, ECE & IARE, Veeraswamy D 
Published: January 2025

Air pollution poses a significant threat to the environment and public health, highlighting the need for effective monitoring systems. This paper introduces an IoT-based air pollution detection and monitoring system built using Arduino. The system incorporates sensors such as MQ135 to measure key pollutants, including carbon dioxide (CO₂), carbon monoxide (CO), and particulate matter. Arduino processes the collected data and transmits it to a cloud platform via Wi-Fi or GSM modules, enabling real-time monitoring and remote access through web or mobile applications .The system also generates alerts when pollutant levels surpass predefined safety thresholds, promoting timely interventions. Its low-cost and modular design ensure scalability and adaptability for various applications, including urban, industrial, and residential environments. The proposed solution demonstrates its reliability and potential in enhancing environmental monitoring and facilitating data-driven pollution management strategies.

Key Words: IoT, Arduino, air pollution monitoring, real-time data, sensors, environmental management
Impact du petit déjeuner dans l’apprentissage et le rendement scolaire des apprenants du primaire de la circonscription de Bacongo, (Brazzaville)
Authors: OKÉMY ANDISSA Nadège , MOUSSAVOU Guy , MOUDILOU Moïse Servais Amédée , OBANDA Laurence 
Published: January 2025

Ce travail de recherche s’intéresse à « l’impact de l’apport du petit déjeuner sur l’apprentissage et le rendement scolaire des apprenants de la circonscription de Bacongo ». Son objectif est de garantir l’éducation des écoliers par l’apport nutritionnel. La méthodologie sur l’approche de l’enquête sur le terrain a été menée et la collecte des données s’est réalisée à travers le questionnaire et les interviews directes avec la population cible. Les résultats issus de cette investigation ont montré qu’environ 72% des encadreurs pensent que la prise du petit déjeuner par les apprenants, les maintiens en éveil, les motive et booste leurs performances de compréhension des contenus notionnels. De même que, 63% des élèves confirment que les sauts du petit déjeuner seraient le facteur bloquant pour leurs réussites scolaires. De ce fait, on peut supposer que la création des cantines scolaires serait une résolution efficace pour augmenter les compétences intellectuelles et des apprenants du primaire.
L’enseignement de la linguistique et de la grammaire française : analyse de quelques opinions des futurs enseignants de français de l’École normale supérieure (ENS) de l’université Marien Ngouabi (République du Congo)
Authors: NKOULA-MOULONGO Solange 
Published: January 2025

Cette réflexion propose une analyse des opinions de 28 étudiants de l’ENS sur les enseignements reçus de grammaire et de linguistique. Structurée en deux principaux points, elle a été menée à partir d’un questionnaire. Il s’agit d’un côté des productions épilinguistiques comme évaluation de la grammaire et de la linguistique et de l’autre, la catégorisation dans les discours. Les réponses relatives à l’évaluation de la grammaire, de la linguistique, de la catégorisation des notions grammaticales et linguistiques ont permis de relever une préférence des apprenants pour la grammaire. Par ailleurs, les réponses relatives à la catégorisation des notions grammaticales et linguistiques ont permis de noter des confusions notionnelles. Quelques exemples peuvent être cités pour en témoigner l’ampleur : la notion de « marqueurs de cohésion » est classée du côté de la grammaire française par 8 apprenants, le terme « énonciation » est pris pour une notion de grammaire française par 5 apprenants et l’expression « catégorie du discours" est classée dans les concepts de linguistique par 3 apprenants… Les productions épilinguistiques sur l’évaluation de la grammaire, de la linguistique, de la catégorisation des notions de grammaire et de linguistique sont les deux orientations de la réflexion. Les résultats laissent entrevoir une certaine insécurité scientifique que devrait prendre en charge les différents enseignements.
Les superviseurs pédagogiques en éducation physique et sportive de Brazzaville et leurs rapports aux styles d’enseignement de Mosston et Ashworth
Authors: MOUDOUDOU LOUBOTA Ghislain Armand , KPAZAÏ Georges , MANDOUMOU Paulin , MBONDZO-KOUMOU Staelle , MIASSOUASSANA Alexia 
Published: January 2025

La présente étude a pour but de documenter le rapport au savoir des superviseurs pédagogiques (inspecteurs et conseillers pédagogiques) en éducation physique et sportive (EPS) relié aux styles d’enseignement de Mosston et Ashwoth (2006). Pour ce faire, vingt superviseurs pédagogiques (inspecteurs et conseillers pédagogiques) ont participé à deux focus group d’une durée de quatre-vingt-dix minutes chacun. L’analyse de contenu des retranscriptions intégrales des entrevues de groupe a servi de technique d’analyse des données. Les résultats obtenus indiquent que les superviseurs (conseillers et inspecteurs) pédagogiques n’ont pas une bonne connaissance de tous les styles d’enseignement de Mosston et Asworth. Par ailleurs, les inspecteurs pédagogiques indiquent que seuls les styles d’enseignement de la « catégorie reproduction » sont pertinents au Congo. À contrario, pour les conseillers pédagogiques, tous les styles d’enseignement sont pertinents. En fin, tous les superviseurs pédagogiques (inspecteurs et conseillers pédagogiques) déclarent avoir besoin d’une formation sur les styles d’enseignement de Mosston et Ashworth afin de mieux accompagner les enseignants d’EPS en exercice.
Questions d’éducation à la santé en milieu scolaire à Madingou au Congo
Authors: NGAYI Lemadre Bellvy , NDZANI Ferdinand , MOUNDZA Patrice 
Published: January 2025

La présente étude analyse les connaissances des apprenants en éducation à la santé en milieu scolaire à Madingou au Congo. Les principaux résultats de cette étude sont issus de la recherche documentaire, des observations directs, des entretiens auprès de 10 enseignants actifs et 2 directeurs d’écoles et les questionnaires d’enquêtes auprès de 60 élèves interrogés de façon simple et aléatoire en 2021. Ils montrent que les apprenants des collèges de la ville de Madingou ont des connaissances sur l’éducation à la santé (90%). L’identification des infections sexuellement transmissibles par les élèves : le Sida (47,5%), la gonococcie (37,5%), et la syphilis (12,5%), en sont la preuve.