bluuebunny/crossref_metadata_2025_split huggingface dataset:
Obstacles and Opportunities Of Implementing Asta Ethics Librarians In Library Information Services In Indonesia
Authors: Abiel Yehuda , Masruri Anis 
Published: July 2023

ABSTRACT

Ethics itself is very closely related to human existence as individuals in society. In society, harmonious coexistence of individuals cannot be separated from ethics that are able to harmonize existing differences. Ethics is also regulated in every religion. All religions teach three main things in their holy books, namely the nature of God, ethics/morality, and rituals/worship. There is no religion that does not teach ethics. The higher the faith, the better the morals. The Librarian Code of Ethics is a starting point for librarians in carrying out their duties, in which there are guidelines for behavior that can be used to avoid unprofessional behavior. This research was conducted using descriptive qualitative research methods supported by literature studies. As many as 6 of the 7 librarians interviewed admitted that they had never heard of Asta Librarian Ethics, while 1 librarian stated that they had heard of Asta Ethics for Librarians, and this shows that this code of ethics is not very popular among librarians. IPI itself has a crucial role in the development of librarianship in Indonesia and the application of an even code of ethics to librarians in Indonesia which is oriented towards excellent service to and satisfaction of users and society in general.

Keywords: Ethics, librarian, organization, indonesia.

OBSTACLES AND OPPORTUNITIES OF IMPLEMENTING ASTA ETHICS LIBRARIANS IN LIBRARY INFORMATION SERVICES IN INDONESIA

ABSTRAK
Etika sendiri sangat erat kaitannya dengan eksistensi manusia sebagai individu yang hidup di tengah-tengah masyarakat. Keharmonisan interaksi antar-individu dalam masyarakat tidak lepas dari etika yang sanggup menyelaraskan perbedaan yang terjadi. Etika pun juga diatur dalam setiap agama. Menurut Agoes (2011) semua agama mengajarkan melalui kitab sucinya tiga hal pokok yaitu hakikat Tuhan, etika/tata susila dan ritual/tata cara beribadah. Tidak ada agama yang tidak mengajarkan etika. Semakin tinggi keimanan seseorang seharusnya menjadi semakin baik etika yang dimilikinya. Kode Etik Pustakawan merupakan pijakan awal bagi para pustakawan dalam melaksanakan tugasnya di tempat ia bekerja, yang di dalamnya memberikan pedoman tingkah laku yang dapat menghindarkan diri dari tindakan yang tidak professional. Penelitian ini dilakukan menggunakan metode penelitian kualitatif deskriptif yang didukung dengan studi literatur. Penulis mencoba mewawancari 7 pustakawan dari 3 perpustakaan perguruan tinggi di Indonesia dan 6 dari 7 pustakawan tersebut mengaku belum pernah sekalipun mendengar tentang Asta Etika Pustakawan. IPI sendiri memiliki peranan krusial dalam perkembangan kepustakawanan di Indonesia dan penerapan kode etik yang merata kepada pustakawan di Indonesia yang berorientasi kepada layanan prima kepada dan kepuasan pemustaka serta masyaarakat pada umumnya.

Keywords: Etika, pustakawan, organisasi, indonesia
Analysis of Communication Effectiveness in the Digital Era as a Communication Media for iGeneration (Gen Z) during the Recovery Period of the COVID-19 Pandemic
Authors: Purnawati Juli , Kurniawati Dewi 
Published: July 2023

ABSTRACT
All sectors are feeling the impact of the Corona virus outbreak, such as education, the economy, tourism, and others. This has also shifted the direct interpersonal communication system to the digital (online) media communication system. With the COVID-19 virus, all universities in North Sumatra, both public and private, received an appeal from the government to implement PSBB (Large-Scale Social Restrictions) and carry out social distancing, where all employees, lecturers, and students of the University of North Sumatra are required to carry out their activities and daily operations at WFH (Work From Home) homes. However, during this recovery period, campus activities began to be carried out offline and also online, so the purpose of this study was to identify and analyze the effectiveness, constraints, and digital communication solutions during the pandemic (COVID-19) and recovery during the COVID-19 pandemic. , in the Master of Communication Science, University of North Sumatra. This research was conducted using a qualitative approach and a descriptive method. The research results show the effectiveness of digital communication during the COVID-19 pandemic and COVID-19 recovery.
Keywords: efektivitas, komunikasi digital, Pandemi COVID-19 dan Pemulihan COVID-19

Analisis Efektivitas Komunikasi di Era Digital Sebagai Media Komunikasi Pada iGeneration (Gen Z) di Masa Pemulihan Pandemi COVID-19 (Studi Deskriptif MIKOM USU 2022)
ABSTRAK
Semua sektor merasakan dampak dari wabah virus Corona, seperti pendidikan, ekonomi, pariwisata, dan lain-lain. Hal ini juga telah menggeser sistem komunikasi interpersonal langsung ke sistem komunikasi media digital (online)(Ardiyanti, 2020). Dengan adanya virus COVID-19, seluruh perguruan tinggi di SUMUT baik negeri maupun swasta mendapat himbauan dari pemerintah untuk menerapkan PSBB (Pembatasan Sosial Berskala Besar) dan melakukan social distancing, dimana seluruh karyawan, dosen, dan mahasiswa Universitas Sumatera Utara diwajibkan untuk melaksanakan kegiatan pekerjaan dan operasional sehari-hari mereka di rumah WFH (Work From Home). Namun pada masa recovery ini, kegiatan kampus mulai dilakukan secara offline dan juga online, sehingga tujuan dari penelitian ini adalah untuk mengidentifikasi dan menganalisis efektifitas, kendala, dan solusi komunikasi digital pada masa pandemi COVID-19 dan pemulihan pada masa pandemi COVID-19, di Magister Ilmu Komunikasi, Universitas Sumatera Utara. Penelitian ini dilakukan dengan menggunakan pendekatan kualitatif dan metode deskriptif. Hasil penelitian menunjukkan efektivitas komunikasi digital selama pandemi COVID-19 dan pemulihan COVID-19.
Kata Kunci : efektivitas, komunikasi digital, Pandemi COVID-19 dan Pemulihan COVID-19
Heart failure with preserved left ventricular ejection fraction in non-obstructive coronary artery disease: clinical utility of heart rate variability
Authors: Grakova E. V. , Kopeva K. V. , Gusakova A. M. , Smorgon A. V. , Akhmedov Sh. D. , Kalyuzhin V. V. , Teplyakov A. T. 
Published: July 2023

Aim. To evaluate the role of heart rate variability in the pathogenesis of chronic heart failure with preserved ejection fraction (HFpEF) in patients with non-obstructive coronary artery disease (CAD).Materials and methods. The cross-sectional study included 65 patients (55.4% were males) with non-obstructive CAD. Non-obstructive CAD (stenosis < 50%) was confirmed by coronary computed tomography angiography. Heart rate variability (HRV) was evaluated by 24-hour Holter monitoring; parameters of time series and spectral analysis were analyzed.Results. Depending on the presence of HFpEF, the patients were divided into 2 groups: group 1 (n = 48) included patients with HFpEF, and group 2 (n = 17) encompassed patients without it. In patients with HFpEF, a statistically significant decrease in the total HRV and parasympathetic effects on the heart rate, mainly at night, as well as increased activity of cerebral ergotropic systems were revealed. In group 1, the values of the time series analysis of HRV and QT dispersion based on the study of RR interval duration (SDANN and SDNNidx) had a significant direct relationship with the level of myocardial stress in diastole, the value of vascular resistance, and the E / e’ ratio. The cut-off values of SDNNidx and pNN50 were identified, that may be used as markers for early diagnosis of HFpEF.Conclusion. In patients with non-obstructive CAD and HFpEF, it is advisable to perform 24-hour Holter monitoring and assess HRV parameters by the time series analysis, which, compared with the spectral analysis, has a closer relationship with the characteristics of left ventricular diastolic function and afterload.
Viability of mononuclear cells in leukocyte concentrates at the stages of their preparation, freezing, and thawing
Authors: Isaeva N. V. , Minaeva N. V. , Utemov S. V. , Sherstnev F. S. , Zorina N. A. , Zmeeva Yu. S. , Butolina M. A. 
Published: July 2023

Aim. To evaluate the viability of mononuclear cells (MNCs) in leukocyte concentrates (LCs) at the stages of their preparation, freezing, and thawing.Materials and methods. The study material included 44 LCs from donors of allogeneic hematopoietic stem cells (HSCs) and 189 autologous LCs from patients with oncohematological disorders. LCs were obtained from donors and patients by leukocytapheresis after mobilization of HSCs. LCs from patients were frozen with dimethyl sulfoxide (DMSO) used as a cryoprotectant at a final concentration of 5% and stored in liquid nitrogen. LCs were thawed before transplantation. A total of 161 LCs were immediately transfused to the recipient after thawing, and 28 LCs were washed from DMSO before transfusion. Flow cytofluorometry was used to determine the percentage of MNC populations that excluded 7-aminoactinomycin D (7-AAD).Results. The viability of peripheral blood MNCs in donors and patients was close to 100%. It was found that leukocytapheresis and cryopreservation with DMSO did not affect the viability of MNCs. The freezing of LCs with DMSO, storage in liquid nitrogen, and thawing resulted in a significant decrease in the content of viable MNCs (p = 0.0025), while no effect of LC storage duration on the viability of MNCs was revealed. Following DMSO removal from LCs, significantly more HSCs remained in a viable state than without washing (94.4 [94.5; 95.2] % vs. 86.7 [67.6; 92.9] %, (p = 0.0051); for other MNC populations, except monocytes, the differences in the viability index were also statistically significant.Conclusion. The viability of MNCs in LCs is recommended to be used as an independent characteristic of the transplant quality. In obtaining LCs and mixing them with the cryoprotectant DMSO, the viability of MNCs does not decrease, while in thawed LCs, it decreases significantly. Thawing of LCs with removal of DMSO allows to achieve the best viability of HSCs and most MNC populations.
Renal venous Doppler ultrasound – a new parameter for predicting outcomes in patients with decompensated heart failure
Authors: Kobalava Zh. D. , Safarova A. F. , Aslanova R. Sh. , Vatsik-Gorodetskaya M. V. 
Published: July 2023

Aim. To assess the frequency, dynamics, and prognostic value of renal venous congestion using Doppler ultrasound in patients with decompensated heart failure (DHF).Materials and methods. A prospective, single-center study included 124 patients with DHF (mean age 70 ± 12 years, 51.6% were males), left ventricular ejection fraction (LVEF) 44 [34; 55] %, N-terminal pro B-type natriuretic peptide (NT-proBNP) 1,609 [591; 2,700] pg / ml. All patients underwent a standard physical examination and laboratory and instrumental tests, including the assessment of the NT-proBNP level. Renal venous blood flow was assessed using pulsed-wave Doppler ultrasound. The presence of continuous renal blood flow was considered as the absence of venous congestion, while intermittent blood flow (two-phase and single-phase flow) indicated venous congestion. Rehospitalization for DHF and reaching a composite endpoint (rehospitalization for DHF and cardiovascular mortality) within 12 months after discharge were selected as endpoints.Results. At admission, continuous renal venous blood flow was observed in 34 (27.4%) patients, intermittent renal venous blood flow was found in 90 (72.6%) patients: two-phase flow in 62 (50%) and single-phase flow in 28 (22.6%) patients with DHF. At discharge, 66 (53.2%) patients had intermittent renal venous blood flow: two-phase flow in 50 (40.3%) and single-phase flow in 16 (12.9%) patients. Correlations of renal venous congestion with the levels of NT-proBNP, serum iron, uric acid, creatinine, LVEF, systolic pressure in the pulmonary artery (SPPA), and the development of acute kidney injury (AKI) were revealed. Persistent renal venous congestion at discharge was significantly associated with a higher probability of rehospitalization for DHF (hazard ratio (HR) 1.93 95% confidence interval (CI) (1.017–3.67); p = 0.044) and a composite endpoint (HR 2.66, 95% CI (1.43–4.96); p = 0.002).Conclusion. In patients with DHF, it is necessary to evaluate renal venous blood flow using pulsed-wave Doppler ultrasound to stratify patients with development of cardiovascular complications within 12 months.
Features of bacterial DNA taxonomy in blood of patients with various metabolic phenotypes of obesity
Authors: Kolesnikova I. M. , Karbyshev M. S. , Gaponov A. M. , Khusnutdinova D. R. , Grigoryeva T. V. , Kamaldinova D. R. , Borisenko O. V. , Makarov V. V. , Yudin S. M. , Roumiantsev S. A. , Shestopalov A. V. 
Published: July 2023

Aim. To study the blood microbiome taxonomy in patients with metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO).Materials and methods. The study included healthy donors without obesity (n = 116) and obese patients who were divided into subgroups with MHO (n = 36) and MUHO (n = 53). Bacterial DNA isolated from blood samples was subject to metagenomic sequencing of the v3–v4 variable region in the 16S rRNA gene. We compared the frequency of isolating certain taxa from the samples and the proportion of these taxa in the total pool of bacterial DNA in the blood.Results. MUHO patients showed an increase in Lachnospiraceae, Ruminococcaceae, and Prevotellaceae, which are the main taxa in gut microbiota. This may indicate greater intestinal permeability in such patients. Obese patients, regardless of the metabolic phenotype of obesity, more often had Rhodobacteraceae, Streptomycetaceae, Leuconostocaceae, and Burkholderiaceae DNA in their blood. Nocardioidaceae, Flavobacteriaceae, Hyphomicrobiaceae, and Gaiellaceae DNA were more frequently present in the blood microbiome of patients with MHO, whereas MUHO patients more often had S24-7, Nocardiaceae, and Helicobacteraceae DNA in their blood. Many members of these families inhabit soil and water, which may indicate increased skin barrier permeability in obese patients. Additionally, a higher number of Helicobacteraceae-positive blood samples in the MUHO patient group may indicate increased translocation from the stomach.Conclusion. Obesity is accompanied by changes in the taxonomic composition of the blood microbiome. Moreover, the nature of the changes depends on the metabolic phenotype of obesity and the permeability of external barriers.
mRNA level of antioxidant genes and activity of NADPH-generating enzymes in rotenone-induced parkinsonism in rats
Authors: Kryl’skii E. D. , Razuvaev G. A. , Popova T. N. , Nikhaev L. E. , Akinina A. I. 
Published: July 2023

Aim. To analyze the mRNA level of genes encoding antioxidant enzymes and the transcription factors Nrf2 and Foxo1 regulating their expression and the activity of glucose-6-phosphate dehydrogenase (G6PDH) and NADPdependent isocitrate dehydrogenase (NADP-IDH) and assess the correlation between these parameters, oxidative status, and motor coordination parameters in rats with rotenone-induced parkinsonism.Materials and methods. The study was performed on male Wistar rats aged 4–6 months and weighing 200–250 g. Parkinsonism was modeled by subcutaneous administration of rotenone for 10 days at a dose of 2.5 mg / kg. To confirm the development of the pathology, motor coordination tests and histological staining of the cerebral cortex and striatum with hematoxylin and eosin were used. The oxidative status was analyzed based on the levels of conjugated dienes, carbonyl amino acid residues in proteins, and α-tocopherol. The enzyme activity was studied spectrophotometrically by the formation of NADPH. Real-time PCR was used to analyze the level of gene mRNA.Results. During the study, an increase in serum and brain concentrations of conjugated dienes, carbonyl amino acid residues, and α-tocopherol was observed in the experimental group of rats compared to the controls. It could be associated with the redistribution of this compound between tissues during pathology development. The animals with experimental parkinsonism, in addition, were characterized by a decrease in the mRNA level of the Sod1, Gpx1, Gsr, Gsta2, Nfe2l2, and Foxo1 genes, as well as the activity of G6PDH and NADP-IDH. In the rats with experimental parkinsonism, a negative correlation of NADPH-IDH activity in the brain with serum α-tocopherol level and a positive correlation with Gpx1 and Foxo1 mRNA levels in the striatum were found. The level of oxidatively modified proteins in the brain of the animals with PD was negatively correlated with the concentration of Gsta2 mRNA in the striatum, while the specific activity of G6PDH in the serum was characterized by the positive relationship with grip strength.Conclusion. The data obtained indicate that the inhibition of transcription of the genes encoding antioxidant enzymes and regulatory factors Nrf2 and Foxo1 contributed significantly to the development of oxidative stress in PD. A decrease in the activity of G6PDH and NADP-IDH led to a decrease in the availability of NADPH, which is a limiting factor in the functioning of the glutathione antioxidant system. Obviously, the inhibition of G6PDH and NADP-IDH was also an important pathogenic factor in the progression of the pathology. Along with a decrease in the content of antioxidant gene mRNA in the brain tissues, the level of α-tocopherol increased in the rats with parkinsonism, which could be the result of an imbalance in the functioning of antioxidant system.
The cytokine profile in obesity and asthma in children
Authors: Tarabrina A. A. , Ogorodova L. M. , Samoilova Yu. G. , Fedosenko S. V. , Fedorova O. S. , Petrov V. A. , Podchinenova D. V. , Boyko A. S. 
Published: July 2023

Background. Childhood obesity is one of the pressing problems in modern healthcare, since it is associated with a high risk of non-communicable diseases, such as bronchial asthma (BA). The aim. To determine the features of cytokine profiles in children with and without BA, depending on body weight and visceral fat area.Materials and methods. At the first stage, 506 Tomsk schoolchildren underwent anthropometry with the calculation of the body mass index (BMI) and measurement of the visceral fat area (VFA) using the InBody 770 analyzer. Fiftyone (51) children from the first stage were included in the second clinical and diagnostic stage. The children were divided into four clinical groups: “Obesity” (n = 17), “Visceral Obesity” (n = 7), “Asthma” (n = 15), and “Healthy Children” (n = 12). In all study participants, the levels of interleukin (IL)-6, IL-8, IL-4, IL-10, and immunoglobulin (Ig) E in the blood serum were determined by the multiplex assay (MagPix and Luminex 200 c analyzers). Statistical data analysis was carried out using the Statistica 10.0 software package and the 4.2.2 version of R.Results. The levels of IL-10 in the “Asthma” (p < 0.006) and “Obesity” (p < 0.008) groups were significantly higher than in the “Visceral Obesity” group. Significantly higher levels of IL-8 were found in patients with asthma (p < 0.003) and obesity (p < 0.003) compared to the “Visceral Obesity” group. Higher concentrations of IL-6 were found in the “Asthma” (p < 0.001) and “Obesity” (p < 0.028) groups compared to the “Visceral Obesity” group.Conclusion. Similar upward changes in IL-6, IL-8, and IL-10 in children with asthma and obesity without a history of asthma may explain the contribution of obesity to a risk of asthma in children, possibly through excessive production of these proinflammatory cytokines that contribute to the implementation of Th2-mediated allergic inflammation.
Preservation of Soft-Bodied Organisms in Early Cambrian Carbonates
Authors: Marusin V.V. , Bykova N.V. 
Published: July 2023

Abstract
—Preservation of soft-bodied organisms as casts is common in the Ediacaran fossil record and extremely rare in Cambrian rocks. Among the factors, limiting fossilization of soft tissues, there is bioturbation–sediment disturbance by burrowing organisms. It is the emergence of burrowing metazoans and associated sediment bioturbation that is thought to be one of the major causes for the disappearance of Ediacaran soft-bodied organisms from the fossil record around ~540 Ma. Here, we study an assemblage of fossils preserved as casts in the Fortunian carbonates of the Olenek Uplift (northeastern Siberian Platform) in association with a typical Fortunian ichnoassemblage. The overall morphology and preservation of the fossils reveal that they comprise microbially induced sedimentary structures and soft-bodied holdfasts. The latter are vaguely reminiscent of some Ediacaran holdfasts, though it is unlikely that they include their phylogenetic descendants. Three-dimensional preservation of the studied fossils was caused by authigenic crystallization of calcite and its further early-diagenetic dolomitization. Our study confirms the critical importance of specific environmental conditions ensuring preservation of soft-bodied organisms as three-dimensional molds and casts. This unique interplay of environmental factors became rare in the Cambrian Period, which was caused by intensification and expansion of bioturbation in marine basins.
WITHDRAWN: Lagging effects and prediction of pollutants and their interaction modifiers on influenza in northeastern China
Authors: Chen Ye , Hou Weiming , Hou Weiyu , Dong Jing 
Published: July 2023

Abstract
Background: Previous studies have typically explored the daily lagged relations between influenza and meteorology, but few have explored seasonally the monthly lagged relationship, interaction and multiple prediction between influenza and pollution. Our specific objectives are to evaluate the lagged and interaction effects of pollution factors and construct models for estimating influenza incidence in a hierarchical manner.
Methods: Our researchers collect influenza case data from 2005 to 2018 with meteorological and contaminative factors in Northeast China. We develop a generalized additive model with up to 6 months of maximum lag to analyze the impact of pollution factors on influenza cases and their interaction effects. We employ LASSO regression to identify the most significant environmental factors and conduct multiple complex regression analysis. In addition, quantile regression is taken to model the relation between influenza morbidity and specific percentiles (or quantiles) of meteorological factors.
Results: The influenza epidemic in Northeast China has shown an upward trend year by year. The excessive incidence of influenza in Northeast China may be attributed to the suspected primary air pollutant, NO2, which has been observed to have overall low levels during January, March, and June. The Age 15-24 group shows an increase in the relative risk of influenza with an increase in PM2.5 concentration, with a lag of 0-6 months (ERR 1.08, 95% CI 0.10-2.07). In the quantitative analysis of the interaction model, PM10 at the level of 100-120 μg/m3, PM2.5 at the level of 60-80 μg/m3, and NO2 at the level of 60 μg/m3 or more have the greatest effect on the onset of influenza. The GPR model behaves better among prediction models.
Conclusions: Exposure to the air pollutant NO2 is associated with an increased risk of influenza with a cumulative lag effect. Prioritizing winter and spring pollution monitoring and influenza prediction modeling should be our focus.
Keywords: Pollutants; Influenza; NO2; Generalized additive model; Time series analysis.