bluuebunny/crossref_metadata_2025_split huggingface dataset:
JWST UNCOVER: Extremely Red and Compact Object at z
phot ≃ 7.6 Triply Imaged by A2744
Authors: Furtak Lukas J. , Zitrin Adi , Plat Adèle , Fujimoto Seiji , Wang 王 Bingjie 冰 洁 , Nelson Erica J. , Labbé Ivo , Bezanson Rachel , Brammer Gabriel B. , van Dokkum Pieter , Endsley Ryan , Glazebrook Karl , Greene Jenny E. , Leja Joel , Price Sedona H. , Smit Renske , Stark Daniel P. , Weaver John R. , Whitaker Katherine E. , Atek Hakim , Chevallard Jacopo , Curtis-Lake Emma , Dayal Pratika , Feltre Anna , Franx Marijn , Fudamoto Yoshinobu , Marchesini Danilo , Mowla Lamiya A. , Pan Richard , Suess Katherine A. , Vidal-García Alba , Williams Christina C. 
Published: July 2023

Abstract
Recent JWST/NIRCam imaging taken for the ultra-deep UNCOVER program reveals a very red dropout object at z
phot ≃ 7.6, triply imaged by the galaxy cluster A2744 (z
d = 0.308). All three images are very compact, i.e., unresolved, with a delensed size upper limit of r

e
≲ 35 pc. The images have apparent magnitudes of m
F444W ∼ 25−26 AB, and the magnification-corrected absolute UV magnitude of the source is M
UV,1450 = −16.81 ± 0.09. From the sum of observed fluxes and from a spectral energy distribution (SED) analysis, we obtain estimates of the bolometric luminosities of the source of L
bol ≳ 1043 erg s−1 and L
bol ∼ 1044–1046 erg s−1, respectively. Based on its compact, point-like appearance, its position in color–color space, and the SED analysis, we tentatively conclude that this object is a UV-faint dust-obscured quasar-like object, i.e., an active galactic nucleus at high redshift. We also discuss other alternative origins for the object’s emission features, including a massive star cluster, Population III, supermassive, or dark stars, or a direct-collapse black hole. Although populations of red galaxies at similar photometric redshifts have been detected with JWST, this object is unique in that its high-redshift nature is corroborated geometrically by lensing, that it is unresolved despite being magnified—and thus intrinsically even more compact—and that it occupies notably distinct regions in both size–luminosity and color–color space. Planned UNCOVER JWST/NIRSpec observations, scheduled in Cycle 1, will enable a more detailed analysis of this object.
Optical and Near-infrared Atmospheric Extinction Coefficients at La Silla
Authors: Sitko Michael L. , Stolker Tomas 
Published: July 2023

Abstract
We used observations obtained at the Rapid Eye Mount (REM) at the La Silla Observatory between 2016 June 7 UT to determine the extinction coefficients of the REM filters currently in use. The observations were obtain on 6 nights, spanning 2016 June UT through 2016 July 4 UT, over a wide range of airmass values, to determine the mean atmospheric extinction coefficients at the La Silla Observatory site. Coefficients in the REM filter sets—Sloan g′, r′, i′, z′, and J, H and K were determined, where the REM infrared filters closely match those of the J, H, and Ks filters of the 2MASS All-Sky Survey.
An Analysis of Pediatric Ophthalmology Content on TikTok
Authors: Borkhetaria Rucha K. , Devireddy Nitya , Cannon Nathan , Soni Ajay , Ely Amanda L. 
Published: July 2023

Purpose:
To assess pediatric ophthalmology–related information on TikTok (ByteDance).

Methods:
The 12 most commonly searched terms from the American Association for Pediatric Ophthalmology and Strabismus website were queried as TikTok hashtags. The top 20 videos for each hashtag were analyzed for views, likes, comments, saves, shares, author status and gender, content, and engagement level ratio (ELR). Subanalysis of the educational videos for quality, understandability and actionability, and medical accuracy using the modified DISCERN (mDISCERN), Patient Education Materials Assessment Tool (PEMAT), and modified Medical Information and Content Index (mMICI) was performed.

Results:

Analysis of 222 videos revealed a cumulative 191,337,973 views. Patients/families created the most videos (60.4%), followed by optometrists (14.4%), other (laypeople/unknown) (9.0%), ophthalmologists (7.7%), non-ophthalmology physicians (4.5%), and nurses (4.1%). Content was predominantly patient experience (56.8%), followed by educational (25.2%), humor (11.7%), self-promotional (3.6%), procedures (0.9%), other (0.9%), advertisements (0.5%), and career (0.5%). Educational videos had a lower ELR than humorous (3.3 vs 8.2,
P
< .001) and patient experience (3.3 vs 5.3,
P
< .001) videos, but more saves than patient experience videos (74 vs 25,
P
= .009). The mDISCERN scores were greater for videos authored by ophthalmologists (3,
P
< .001) and optometrists (2.5,
P
< .001) compared to lay-people (1.5). Ophthalmologist PEMAT understandability scores were greater than non-ophthalmology providers' (95.5% vs 67.4%,
P
= .002). There was no difference in PEMAT actionability (
P
= .743) or mMICI scores among the author subgroups (
P
= .206).

Conclusions:
Pediatric ophthalmology content on Tik-Tok ranges in quality and understandability. Additional research is needed to help promote posts created by eyecare providers to ensure evidence-based medical content reaches pediatric patients and their families.

[
J Pediatr Ophthalmol Strabismus
. 2024;61(2):90–97.]
De Giza à la mer Rouge : une équipe d’ouvriers du règne de Khoufou au Ouadi Sannourمن الجيزة إلى البحر الأحمر: فريق عمَّال من عهد خوفو في وادي سنّور
Authors: Ciavatti Aurore 
Published: July 2023

La récente découverte de tessons inscrits au nom d’équipes royales du règne de Khoufou au Ouadi Sannour sur les sites WS 005 et WS 0013 fournit un marqueur chronologique essentiel à la compréhension de ces implantations. Les parallèles observés au Ouadi el-Jarf et identifiés à Giza apportent un nouvel éclairage sur la relation entre l’exploitation du silex du Ouadi Sannour et les autres grandes réalisations royales entreprises sous la IVe dynastie.
Interventi educativi nel periodo perioperatorio del paziente sottoposto a cardiochirurgia: una scoping review della letteratura
Authors: Filomeno Lucia , Minciullo Andrea , Gabellini Silvia 
Published: July 2023

Lâ€™assistenza al paziente in cardiochirurgia Ã¨ molto delicata poichÃ© si rivolge ad una persona molto spesso fragile o anziana che ha paura, Ã¨ preoccupata ed ansiosa. Lâ€™esposizione a livelli elevati di stress nel pre e post-operatorio influisce sulla funzionalitÃ corporea e puÃ² aggravare i sintomi della malattia cardiovascolare, sviluppando un disturbo post traumatico da stress che provoca unâ€™estensione dei tempi di recupero, un aumento del dolore post-operatorio, un recupero piÃ¹ lento dallâ€™anestesia, una maggiore richiesta di farmaci e una degenza ospedaliera prolungata. In questo contesto, lâ€™infermiere attua interventi educativi volti a informare e sensibilizzare i pazienti su ciÃ² che sperimenteranno, riducendo cosÃ¬ il senso di ansia, aumentando le loro conoscenze e gettando le basi per un recupero piÃ¹ consapevole.
The barriers of joining in vitro fertilization programs among infertile couples in developing countries: A scoping review
Authors: Dewi Andriana K , Wicaksana Anggi L , Lutfi Muhammad , Dewanto Agung 
Published: July 2023

Objective:
To determine the barriers of joining in-vitro fertilization (IVF) programs among infertile couples in developing countries.

Methods:
This study assessed infertile couples and the barriers or associated factors resulting in delayed decision-making of joining IVF program by searching databases PubMed, ScienceDirect, EBSCO, ClinicalKey, and Cochrane Library from inception until December 31, 2021. Additional search strategies were snowballing literature search and citation tracking.

Results:
Eleven articles were included in the scoping review. The cost was the greatest barrier of joining IVF program. Limited access and lack of assisted reproductive technology centers, few qualified infertility trained staff, insufficient government support, low priority in government policy, along with sociocultural factors, such as religion and false beliefs or myths were also majorly considered to be associated obstacles.

Conclusions:
The main barrier associated with IVF program among infertile couples in developing countries is the high cost of the IVF services.
Artificial Intelligence and Network Pharmacology Reveal the Medication Rules of Professor Wang Yu-Ying in the Treatment of Climacteric Syndrome
Authors: Hu Meng-Yuan , Yi Tian-Xing , Liu Qi-Rui , Zhang Xin-Yu , Chen Ai-Ping , Wang Yu-Ying , Lu Yi 
Published: July 2023

Abstract

Objective:
The objective of this study was to explore the medication rules and academic ideas of Professor Wang Yu-Ying in the treatment of climacteric syndrome (CLS) and to predict new prescriptions.

Materials and Methods:
The characteristics of frequency, clustering, four properties, and five flavors were analyzed, and new prescriptions were predicted through an artificial intelligence (AI)-based method. The potential pathways of new prescriptions were explored through network pharmacology-based analysis.

Results:
The top 16 medicinals used by Professor Wang Yu-Ying in the treatment of CLS included Danggui, Longgu, Muli, Fuling, Chuanxiong, Gancao, Xiangfu, and Tusizi. The AI method was applied to predict the basic prescription for treating CLS: Danggui 15 g, Duanlonggu 30 g, Duanmuli 30 g, Fuling 28 g, Chuanxiong 10 g, Gancao 6 g, Xiangfu 12 g, Tusizi 14 g, etc., Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the pathogenesis of CLS might be related to the estrogen pathway, involving typical steroid responses.

Conclusions:
This study summarized Professor Wang’s medication experience in the treatment of CLS based on the data mining of clinical diagnoses and treatment cases. The AI method was used to predict the new prescription of CLS treatment, which was found to be reasonable by network pharmacology studies on its multi-target and multi-pathway mechanisms.
Glioblastoma multiforme: Case report of an unusual presentation
Authors: Samala Niveditha , Harihar Chilukuri 
Published: July 2023

Abstract
Glial tumors account for about 60% of all primary brain tumors. About one-third of patients suffer deficits in one or more cognitive domains, of which language difficulties may be mistaken for confusion. A 60-year-old male who was brought to the medical outpatient department (OPD) on November 14, 2022, with complaints of mental confusion, talking irrelevantly, and increased sleep for 20 days. As the patient had irrelevant talk, he was referred to psychiatry OPD. The psychiatric evaluation revealed word-finding difficulty, memory impairment, and confabulation. His physical examination was normal, but the Montreal Cognitive Assessment Scale score was 8. A provisional diagnosis of organic amnesic syndrome, not induced by alcohol and other psychoactive substances (F04), was made. Plain computed tomography scan brain revealed a large cystic and solid lesion in the left capsuloganglionic region extending to left thalamic and temporal regions with severe perilesional vasogenic edema suggestive of glioblastoma multiforme with midline shift of 5.6 mm. The case was immediately referred to the neurosurgery department for further management. He was treated there with dexamethasone to reduce edema and was referred to a cancer center for chemotherapy and radiotherapy. The patient was put on chemotherapy and passed away on January 21, 2023, before that could happen. Any case with recent onset of neuropsychiatric symptoms needs thorough cognitive assessment and a high index of suspicion to rule out organic causes. Informed consent to submit the case report for publication was obtained from the son of the patient.
Substance use prevalence and associated factors among Indian college students: A narrative review
Authors: Pradeep Kumar PC , Antony Sojan , Ammapattian Thirumoorthy , Kishor M , Sadashiv Megha 
Published: July 2023

Abstract
Substance use among college students is increasing in India. This may be linked to a few contextual factors associated with developmental changes. This narrative review used articles about substance use prevalence among college students in India published between 2010 and 2021. Keywords such as college students, undergraduate students, university, India, substance use, drug use, and drug addiction were used in PubMed, Google Scholar, and ProQuest databases. A total of 12 articles were included in the study. Overall, substance use prevalence among college students ranged from 17.15% to 60.26%. Substance use was higher among professional course students (medical: 17.15% to 60.26% and engineering: 26.87% to 47%.) than general degree (arts, commerce, and science) students (31.3% to 31.8%). Tobacco, alcohol, and cannabis were the most used substances. Engineering and medical students had greater accessibility and affordability to illicit substances than general degree students. Stress, peer pressure, curiosity, social celebration, health and academic benefits, family and personal problems, easy availability, and experimental use were associated with substance use. This study has generated insight into many factors associated with substance use among college students in India.
Cytomorphological traits of fine-needle aspirates of hyalinizing trabecular tumor of the thyroid gland: A brief report
Authors: Wang Fei , Liu Yufei 
Published: July 2023

ABSTRACT

Background:
The incidence of thyroid tumor is increasing, and preoperative diagnosis of hyalinizing trabecular tumor (HTT) is difficult.

Aim:
To investigate the cytological features of HTT of the thyroid gland.

Settings and Design:
A retrospective observational study.

Materials and Methods:
Ultrasonography, preoperative needle aspiration cytology, postoperative histopathology, immunohistochemistry, and BRAF V600E gene test were performed in five patients with HTT to analyze the pathological characteristics of the patients and review the relevant literature.

Results:
Four female and one male patients with HTT were recruited. Fine-needle aspiration cytology (FNAC) showed bloodstained background tumor cells with multiple morphologies. The tumor cells exhibited ovoid nuclei, abundant cytoplasm, fine chromatin, nuclear crowding and overlapping, and small nucleoli. Focal nuclear pseudoinclusions and grooves were present. No papillary structures or psammoma bodies were observed. In all cases, tumor cells were radially distributed around the eosinophilic extracellular matrix. In 40% (2 in 5) of cases, trabecular patterns of elongated tumor cells were present, with their nuclei staggered along the longitudinal axis of tumor cells in the trabeculae. FNAC suggested two cases of HTT and three cases of papillary thyroid cancer. Post-operational biopsy indicated they were HTT cases.

Conclusion:
HTT is a rare thyroid tumor with non-specific clinical manifestations. It can be misinterpreted as papillary thyroid carcinoma by FNAC. However, its cytomorphological traits are helpful in the diagnosis. In combination with FNAC, immunohistochemistry, and molecular testing, HTT can be accurately diagnosed.
Influence of dengue endemicity on malaria identification by automated hematology analyzer – Beckman Coulter LH750: A hospital-based cross-sectional study
Authors: Kini Reshma Gopal , Manoj Nidhi , Amin Ashima N. , Moras Christol Blanch , Marla Nisha J. 
Published: July 2023

ABSTRACT

Aim:
Automated hematology analyzers have been used to develop indices and algorithms for diagnosing malaria. We believe that the practical utility of such indices depends on the infection profile in the community since the type of infection determines the hematological parameters and consequently their power to discriminate malaria. Our region is endemic for malaria and dengue. Our aim was to verify the utility of the published malaria factor (MF) in our setting.

Materials and Methods:
Anticoagulated blood from clinically suspected cases of malaria and dengue were analyzed. The standard deviation and mean (M) values of all the leukocytes were obtained and the MF was calculated.

Results:
The MF showed a sensitivity and specificity of 75% and 55.1% in identifying malaria at a cutoff of 4.2 when the control group (CG) included dengue-positive (DP) patients and a sensitivity and specificity of 93.4% and 65.2% when the CG did not include DP cases. Using another set of parameters, we developed a Malaria Discriminant Index which showed a sensitivity and specificity of 94.4% and 73.9% in identifying malaria in the absence of dengue at a cutoff of 1.19 and a sensitivity and specificity of 85.5% and 61.7% at a cut off of 1.26 when dengue patients were included in the CG.

Conclusion:
This study emphasizes the need to verify the utility of indices/factors developed in regions not having similar endemic profiles before utilizing them in the clinical setting as other infections can influence the discriminant capacity.
Chronic obstructive pulmonary disease – A neglected and underestimated chronic lung disease in India: A large single-center study in India
Authors: Patil Shital , Patil Deepak , Gondhali Gajanan 
Published: July 2023

ABSTRACT

Background:
Chronic obstructive pulmonary disease (COPD) is more prevalent chronic respiratory illness with significant morbidity and mortality, underdiagnosed and inadequately treated in India. Our objectives of study were to analyze the disease awareness and knowledge, diagnostic patterns, and treatment trends including rational inhalation treatment in COPD in the rural settings.

Materials and Methods:
Prospective, observational, questionnaire-based study conducted during July 2013 to January 2020 included 12,000 cases of COPD confirmed by spirometry with chronic respiratory symptoms as cough, sputum production, and shortness of breath. In this study, we assessed disease knowledge, spirometry use, oral or inhalation treatment methods used to all patients before enrollment by applying questionnaire. Statistical analysis was done using the single proportion test.

Results:
Inhalation treatment use was documented in 58% COPD cases, 31% cases levosalbutamol monotherapy, 18% cases levosalbutamol plus beclometasone, and 9% cases either formoterol plus budesonide or salmeterol plus fluticasone (P < 0.0001). Oral medicines use is documented in 42% COPD cases, 16% cases theophylline, 7% cases salbutamol, and 19% cases oral steroids (P < 0.0001) We have documented that 43% study cases were not accepting the diagnosis and convinced for rational inhalation therapy labeled as “Difficult patients” and 9% patients were taking either formoterol plus budesonide or salmeterol plus fluticasone with or without tiotropium due to cost factor versus 91% are on either oral or other inhalation treatment, labeled as “difficult treatment” and oral medicines were offered in 42% COPD cases by treating doctors over inhalation treatment labeled as “difficult doctor.” We have observed 3% study cases were aware about their illness COPD disease, 54% are not having knowledge about disease, and 43% cases are not accepting the COPD diagnosis (P < 0.0001).

Conclusion:
COPD is a neglected and underestimated chronic lung disease in India, especially in the rural settings. More awareness is recommended with regard to disease knowledge and rational inhalation treatment and COPD definitely needs frontline place in National Health Mission in coming days to prevent morbidity and mortality.
Femoral hernia: Treatment delay and cause of death – A case report and an integrative review
Authors: Hassan Yaqoob , Shahma Abu , Anees Afzal , Kumar Susheel 
Published: July 2023

ABSTRACT
Femoral hernia is an uncommon entity in males and is limited to case reports in the medical literature. Because of the narrow neck of the femoral canal, a femoral hernia can easily incarcerate and/or strangulate. Surgical intervention is the only option for definitive treatment. We report the case of a 59-year-old male patient who presented with a 10 days history of generalised abdominal pain, distension, and a few episodes of vomiting. The patient was resuscitated, and contrast-enhanced CT tomography revealed a left femoral hernia as well as features of small bowel obstruction. A gangrenous ileal loop with perforation within the left femoral canal was discovered after surgery. The patient underwent ileal resection and ileostomy, followed by primary femoral ring repair. However, on postoperative day 3rd, the patient developed a sudden cardiac arrest and died. Proper referral, early diagnosis, and treatment are vital in cases of femoral hernia to avoid such a fatal outcome and could have changed the prognosis of the patient. It is important for peripheral health-care providers to pay attention to persistent abdominal symptoms and to be aware of the proper and timely referral.
Role of high-fidelity simulation in obstetrics ultrasound training: A fresh perspective in the COVID era
Authors: Mijar Mahesh , Dsouza Lenon J. , Monteiro Berton Craig , Bhat Malathi S. , Kamath Tanushree 
Published: July 2023

ABSTRACT

Context:
Obstetric sonography is one of the cornerstones in radiology. The exposure of radiology residents in this field is not adequate during their residency life; hence, simulation techniques can be used to bridge the knowledge gap and improve their skills.

Aims:
The study aimed to evaluate the impact of high-fidelity obstetric sonography simulation in resident training and competency testing.

Design:
The study design involves interventional longitudinal cohort study.

Methods:
The study was conducted among 15 radiology residents with the use of Vimedix high-fidelity Ultrasonography simulator. Seven sessions were conducted, following which the evaluation of the training program was done using the Kirkpatrick training evaluation model. The resident’s reaction was recorded using the questionnaire, and the change in knowledge was ascertained by the pretest and posttest. A change in behavior was recorded using a questionnaire in the 6-month follow-up.

Results:
All the domains showed a positive trend after the session three and session seven. The residents were more confident and had an overall improved satisfaction of 97.4% regarding training. The Cronbach’s alpha test for this study was 0.812 for session three and 0.867 for session seven. An upward trend was seen in the results of the pretest and posttest scores with P < 0.01. The average pretest mean score was 11.3, and the average posttest mean score was 21.4. A 6-month follow-up showed nearly 95% of the individuals found simulation to be helpful in their daily day-to-day practice.

Conclusions:
High-fidelity simulators can be used as an adjunct to conventional training in obstetric sonography training of radiology residents.