bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantifying stream-loss recovery in a spring using dual-tracer injections in the Snake Creek drainage, Great Basin National Park, Nevada, USA
Authors: Humphrey C. Eric , Gardner Philip M. , Spangler Lawrence E. , Nelson Nora C. , Toran Laura , Solomon D. Kip 
Published: March 2023

AbstractSimultaneous short-pulse injections of two tracers (sodium bromide [Br–] and fluorescein dye) were made in a losing reach of Snake Creek in Great Basin National Park, Nevada, USA, to evaluate the quantity of stream loss through permeable carbonates that resurfaces at a spring approximately 10 km down drainage. A revised hydrogeologic cross section for a possible flow path of the infiltrated Snake Creek water is presented, and the results may inform water management in the region. First arrival and peak concentration of the two tracers occurred at 9.5 and 12.7 days after injection, respectively. Fracture transport simulations indicate that Br– preferentially diffuses into immobile regions of the aquifer, and this diffusive flux is likely responsible for the major differences in the breakthrough curves. When considering the diffusive tracer flux, total apparent Br– and fluorescein dye recoveries were 16.9–22.1% and 21.7–24.3%, respectively. These findings imply that consideration of diffusive flux and long-term monitoring in fracture-dominated flow may support accurate quantification of tracer recovery. In addition, the apparent power law slopes of the breakthrough tails for both tracers were steeper at early times than have been attributed to heterogeneous advection or channeling in meter-scale tests, but the late-time Br– power law slope becomes less steep than has been attributed to diffusive exchange. These deviations may reflect fracture transport patterns that occur at larger scales.
Rockfall susceptibility analysis through 3D simulations in marine protected areas of the Portofino coastline: case studies of San Fruttuoso and Paraggi bays
Authors: Clemente Jon Ander , Spizzichino Daniele , Leoni Gabriele , Marchese Alessandra , Uriarte Jesus A. , Morales Tomás , Wilting Rolf , Vojinovic Zoran , Faccini Francesco 
Published: March 2023

AbstractThe research focuses on the assessment of the potential geomorphological hazards affecting the stability of the Promontory of Portofino (Regional Natural Park of Portofino, Northern Italy), mainly on the bays of San Fruttuoso and Paraggi. The study area constitutes one of the most representative and most populated environments, both by locals and tourists, of the entire Liguria area. For this reason, there is a growing need for investigation on the natural dynamics of these landscapes, based on detailed topographic information. The research starts from a regional geological and geomorphological analysis specific to the study area, combined with a multi-model comparison algorithm (M3C2), which allows comparing two LiDAR datasets acquired in 2008 and 2020, respectively, to assess the overall dynamics of the promontory development. Then, a detailed study of San Fruttuoso and Paraggi bays, two key points for visitors and therefore for management, is performed. Three-dimensional modeling of rockfalls is carried out, which allows the development of a specific management oriented to the use of nature-based solutions (NBSs) strategies, respecting the environment and increasing safety against instability processes in these areas.
Identification of predictors for neurological outcome after cardiac arrest in peripheral blood mononuclear cells through integrated bioinformatics analysis and machine learning
Authors: Li Zhonghao , Qin Ying , Liu Xiaoyu , Chen Jie , Tang Aling , Yan Shengtao , Zhang Guoqiang 
Published: March 2023

AbstractNeurological prognostication after cardiac arrest (CA) is important to avoid pursuing futile treatments for poor outcome and inappropriate withdrawal of life-sustaining treatment for good outcome. To predict neurological outcome after CA through biomarkers in peripheral blood mononuclear cells, four datasets were downloaded from the Gene Expression Omnibus database. GSE29546 and GSE74198 were used as training datasets, while GSE92696 and GSE34643 were used as verification datasets. The intersection of differentially expressed genes and hub genes from multiscale embedded gene co-expression network analysis (MEGENA) was utilized in the machine learning screening. Key genes were identified using support vector machine recursive feature elimination (SVM-RFE), least absolute shrinkage and selection operator (LASSO) logistic regression, and random forests (RF). The results were validated using receiver operating characteristic curve analysis. An mRNA-miRNA network was constructed. The distribution of immune cells was evaluated using cell-type identification by estimating relative subsets of RNA transcripts (CIBERSORT). Five biomarkers were identified as predictors for neurological outcome after CA, with an area under the curve (AUC) greater than 0.7: CASP8 and FADD-like apoptosis regulator (CFLAR), human protein kinase X (PRKX), miR-483-5p, let-7a-5p, and let-7c-5p. Interestingly, the combination of CFLAR minus PRKX showed an even higher AUC of 0.814. The mRNA-miRNA network consisted of 30 nodes and 76 edges. Statistical differences were found in immune cell distribution, including neutrophils, NK cells active, NK cells resting, T cells CD4 memory activated, T cells CD4 memory resting, T cells CD8, B cells memory, and mast cells resting between individuals with good and poor neurological outcome after CA. In conclusion, our study identified novel predictors for neurological outcome after CA. Further clinical and laboratory studies are needed to validate our findings.
Auswirkungen körperlicher Aktivität auf Status epilepticus im Tiermodell
Authors: van den Bongard Franziska , Gowik Julia Kristin , Reinsberger Claus 
Published: March 2023

ZusammenfassungHintergrundDie Evidenz zum Einfluss körperlicher Aktivität (kA) auf die Anfallsfrequenz in Humanstudien ist niedrig.ZielLiteraturbasierte narrative Darstellung des Einflusses von kA auf Status epilepticus (SE) im Tiermodell.Material und MethodeAuf Basis einer systematischen Literaturrecherche wurden kontrollierte, sportliche Interventionsstudien im Tiermodell für alle Anfallsmodelle sowie Belastungsformen und Modalitäten eingeschlossen, die den Einfluss auf klinische Endpunkte wie Anfallsfrequenz, Latenz und Intensität von Anfällen oder epilepsietypische Aktivität im EEG untersuchten.ErgebnisseEs wurden 33 Studien mit 37 Interventionen (Ausdauer‑, Schwimm- oder Krafttrainings verschiedener Intensität, Dauer und Frequenz) eingeschlossen, im Rahmen derer eine Trainings- mit einer Kontrollgruppe verglichen wurde. Die untersuchten Endpunkte waren sehr heterogen und beinhalteten unter anderem epilepsietypische Aktivität im EEG, Latenz bis zum ersten Anfall, Stärke der Symptome oder Anfallsfrequenz. Insgesamt zeigte sich nach 20 Interventionen ein positiver Effekt, nach 9 Interventionen ein heterogener Effekt (positiv oder ausbleibend), nach 6 Interventionen ein ausbleibender Effekt und nach 1 Intervention ein positiver und ein negativer Effekt bezüglich der untersuchten klinischen Endpunkte.SchlussfolgerungIm Tiermodell scheint kA keinen relevanten negativen Einfluss auf anfallsassoziierte Endpunkte zu haben und wirkt sich tendenziell in den meisten Fällen, z. B. hinsichtlich der Anfallsfrequenz, positiv aus. Diese Ergebnisse sollten zur Untersuchung des Einflusses von kA auf die Anfallsfrequenz in Humanstudien motivieren.
Plasma chemistry and hematology reference values in wild nestlings of White-tailed Sea Eagles (Haliaeetus albicilla): effects of age, sex and hatching date
Authors: Ferrer Miguel , Evans Rhian , Hedley Joanna , Hollamby Simon , Meredith Anna , Morandini Virginia , Selly Owen , Smith Claire , Whitfield D. Philip 
Published: March 2023

AbstractStudies on normal concentration of blood constituents of free-living birds are not very common. An adequate knowledge of blood chemistry is greatly recommended for those projects involving research and management of populations as far as they can be valuable for the assessment of the nutritional levels and health status of species. No previous published reports on these parameters from this species are available. The aim of this study was to obtain representative reference measures for hematologic and biochemical values in free-living clinically healthy wild White-tailed Sea Eagle nestlings (Haliaeetus albicilla). In addition, we investigated potential relationships between blood parameters, sex, age and hatching dates. Blood samples were obtained as part of routine monitoring and management when wild chicks were removed from their nest as part of a reintroduction program prerelease health check. A total of 83 nestlings, 43 males and 40 females, between 41 and 66 days of age (mean = 54.22, SD = 5.7), were sampled. Significant differences between sexes were found. Among hematological parameters, MCH, lymphocytes P and thrombocytes showed significant differences between males and females. In biochemical parameters, significant differences were found only in calcium, CK and LDH between sexes. No effect was found of age of the nestling when the sample was taken in any of the analyzed hematological parameters. No other significant relationships were found between biochemical parameters and other considered explanatory variables. Hatching date showed no relationship with blood parameters excepting urea. Urea was the only variable showing a strong relationship with hatching date, with those nestlings hatching later in the season showing higher urea concentration.
Tool-based renewable energy system planning using survey data: A case study in rural Vietnam
Authors: Hart Maria C. G. , Eckhoff Sarah , Breitner Michael H. 
Published: March 2023

AbstractRenewable energies provide effective sustainable development by raising living standards, accelerating economic growth, and mitigating pollution. However, specifically in developing countries, the lack of information, data, and local expertise challenges the design process and long-term success of renewable energy systems. Following the call for inter-disciplinary, solution-oriented research, this work uses a design science research-approach to facilitate multi-energy planning. The decision support system NESSI4D is developed, which considers site-specific economic, environmental, technological, and social factors and is tuned for stakeholder needs in developing countries. Following a step-by-step process model manual, the artifact’s applicability is demonstrated in a use case for a rural community in Thua Thien-Hue, Vietnam. Missing load data are synthesized from the TVSEP with the software RAMP. The results show that the implementation of renewable energy technologies only enables affordable, low-emission electrification with governmental financial incentives. Several sensitivity tests illustrate the impact of changing assumptions and highlight the importance of detailed analyses with highly specialized tools. The demonstrating use case validates the method’s relevance for research and practice towards the goals of effective sustainable development.
Pre-school Skills and School-Age Reading Comprehension in Children on the Autism Spectrum: A Preliminary Investigation
Authors: Paynter Jessica , O’Leary Kate , Westerveld Marleen 
Published: March 2023

AbstractWe explored reading comprehension development in children on the spectrum from pre-school to the first (YOS1) and third year of schooling (YOS3). Children were first assessed on meaning-related skills in pre-school. Forty-one children completed follow-up assessments of reading comprehension, reading accuracy, and listening comprehension in YOS1. Nineteen returned for assessments of reading accuracy, reading comprehension, and listening comprehension in YOS3. Children showed poorer reading comprehension than reading accuracy at both timepoints. Reading comprehension, reading accuracy, and listening comprehension were significantly concurrently correlated. Pre-school receptive vocabulary was a significant predictor of YOS3 reading comprehension. Results from this preliminary investigation highlight the potential for early identification of children on the spectrum at risk for reading comprehension difficulties.
The dispersion of climate change impacts from viticulture in Ticino, Switzerland
Authors: Bardsley Douglas K. , Bardsley Annette M. , Conedera Marco 
Published: March 2023

AbstractClimate change is having complex impacts on agriculture worldwide, including viticultural systems in mountainous areas such as the canton of Ticino in southern Switzerland. Here, socio-ecological qualitative research is used to examine how vignerons are experiencing and responding to climate change. Even in wealthy Switzerland, with highly developed technical capabilities and support services, the immediate climate change impacts are driving major changes across industry, community, and place. Some change is positive in the short term, such as increased rates of grape development. Negative changes are associated with more extreme droughts, storms, and wet periods, which are increasing disease and pest control requirements. Niche adaptation opportunities exist, but as vignerons adjust their behaviors, more complex socio-ecological impacts are emerging and impacting across landscapes. Professional vignerons are adjusting their phytosanitary management systems: increasing monitoring, optimizing their chemical use, and shifting the susceptible and labor-intensive Merlot variety onto the valley floors to reduce costs. Part-time vignerons are trying to adapt, but are voicing concerns about the difficulties of the new management demands. The result is that changes in climate threaten the established regional niche of high-quality Merlot production in association with terraced landscapes. As decision-makers aim to adapt to climate change, they will need to support local learning to manage the immediate risks to both Professional and Part-time vignerons, as well as the broader risks that are dispersing across society.
Who’s afraid of reverse mereological essentialism?
Authors: Oderberg David S. 
Published: March 2023

AbstractWhereas Mereological Essentialism is the thesis that the parts of an object are essential to it, Reverse Mereological Essentialism is the thesis that the whole is essential to its parts. Specifically—since RME is an Aristotelian doctrine—it is a claim not about objects in general but about substances. Here I set out and explain RME as it should be understood from the perspective of the Aristotelian-Scholastic tradition, as well as proposing a kind of master argument for believing it. A number of objections (many of which have been raised by Kathrin Koslicki or Robert Koons) are then considered, the replies to which help further to clarify and motivate RME. The final section considers some important questions concerning parts and matter in light of Ross Inman’s recent defence of RME under the guise of what he calls Substantial Priority. Considering these questions further illustrates right and wrong ways of understanding RME. Overall, the case for Reverse Mereological Essentialism is strong albeit with a number of difficulties that need to be resolved through further investigation.
Relevance of body composition in phenotyping the obesities
Authors: Salmón-Gómez Laura , Catalán Victoria , Frühbeck Gema , Gómez-Ambrosi Javier 
Published: March 2023

AbstractObesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia. Body mass index (BMI) remains the most frequently used tool for classifying patients with obesity, but it does not accurately reflect body adiposity. In this document we review classical and new classification systems for phenotyping the obesities. Greater accuracy of and accessibility to body composition techniques at the same time as increased knowledge and use of cardiometabolic risk factors is leading to a more refined phenotyping of patients with obesity. It is time to incorporate these advances into routine clinical practice to better diagnose overweight and obesity, and to optimize the treatment of patients living with obesity.
A review of spatial characteristics influencing circular economy in the built environment
Authors: Zhang Ning , Gruhler Karin , Schiller Georg 
Published: March 2023

AbstractIndustrialization, population growth, and urbanization are all trends driving the explosive growth of the construction industry. Creating buildings to house people and operate industry, together with building infrastructure to provide public services, requires prodigious quantities of energy and materials. Most of these virgin materials are non-renewable, and resource shortages caused by the development of the built environment are becoming increasingly inevitable. The gradually evolved circular economy (CE) is considered a way to ease the depletion of resources by extending service life, increasing efficiency, and converting waste into resources. However, the circularity of construction materials shows heavy regional distinctness due to the difference in spatial contexts in the geographical sense, resulting in the same CE business models (CEBMs) not being adapted to all regions. To optimize resource loops and formulate effective CEBMs, it is essential to understand the relationship between space and CE in the built environment. This paper reviews existing publications to summarize the research trends, examine how spatial features are reflected in the circularity of materials, and identify connections between spatial and CE clues. We found that the majority of contributors in this interdisciplinary field are from countries with middle to high levels of urbanization. Further, the case analysis details the material dynamics in different spatial contexts and links space and material cycles. The results indicate that the spatial characteristics can indeed influence the circularity of materials through varying resource cycling patterns. By utilizing spatial information wisely can help design locally adapted CEBMs and maximize the value chain of construction materials.
The effect of shear-dependent flocculation on the multimodality of effective particle size distributions in a gravel-bed river during high flows
Authors: Maltauro R. , Stone M. , Collins A. L. , Krishnappan B. G. , Silins U. 
Published: March 2023

Abstract
Purpose
Multimodal effective particle size distributions (EPSDs) develop as flocculation and particle breakage occur dynamically in a fluid shear and such distributions have been previously reported in coastal and estuarine waters to understand flocculation processes. Here, we use time varying multimodal EPSDs and hydraulic parameters (discharge and bed shear stress) to assess freshwater flocculation in a gravel-bed river in southern Alberta, Canada.

Methods
Instantaneous discharge, volume concentration (VC), and EPSD of suspended solids were measured during three high discharge events at four study sites in a 10 km reach of the Crowsnest River. The EPSD and VC of suspended solids (< 500 µm) were measured in the centroid of flow with a LISST-200x. Bed shear stress for measured discharge was obtained using a flow model, MOBED.

Results
Multimodal EPSDs consisted of primary particles, flocculi, microflocs, and macroflocs. Shear dependent flocculation was consistently observed for all sites and events, due to low and high shear stress flocculation, particle breakage, and mobilization of tributary sub-catchment derived particles. Higher shear stress limited flocculation to smaller floc sizes, while lower bed shear stress conditions created higher volumes of macroflocs.

Conclusion
Flocculation and particle breakage processes based on relationships between particle size and hydraulic properties presented herein have implications for advancing fine sediment transport models by a variable cohesion factor as a function of floc size class.
Reimagining Freire: beyond human relations
Authors: Jones Naya 
Published: March 2023

AbstractBy bridging critical pedagogy and environmental praxis, the contributions in this forum build on Freire’s legacy while stretching his work. As the authors attend to more-than-human life, they theorize and enact relational ways of knowing. Through participatory and multisensory pedagogies, they counter dichotomies between nonhuman and human nature, student and teacher. In this response, I consider how this (re)centering of more-than-human relations expands—and counters—Freire’s thinking, including how he articulates humanization as a primary, liberatory aim of teaching and (un)learning. Along with insights from Black geographies and Black feminist ecologies, bell hooks guides my response. hooks critiqued and engaged with Freire’s work with radical care, with space for complexity and accountability. This way of reading feels particularly suited to this forum, as the authors reimagine Freire’s contributions to critical (environmental) pedagogy for the twenty-first century and beyond.
Umgang mit subjektiv erlebten Coronarisiken: Sichtweisen junger chronisch kranker Erwachsener
Authors: Röhnsch Gundula , Flick Uwe 
Published: March 2023

Zusammenfassung
Hintergrund
Junge Erwachsene mit chronischen Erkrankungen gelten als Gruppe, die durch Corona gefährdet ist. Ob und wie die Betroffenen sich zu schützen versuchen, welche Risikowahrnehmungen sie verdeutlichen und wie der Lockdown erlebt wird, dazu mangelt es an Erkenntnissen primär im deutschen Sprachraum.

Ziele und Fragestellung
Im Beitrag wird analysiert, welches Coronaschutzverhalten junge chronisch kranke Erwachsene berichten, welche Risikowahrnehmungen sie aufweisen und wie sie den Lockdown erleben.

Material und Methoden
Mit n = 59 jungen Erwachsenen (häufig Studierende oder Auszubildende), die von Typ‑1-Diabetes (n = 16), Krebs (n = 18), chronisch-entzündlichen Darmerkrankungen (n = 21) oder von bestimmten seltenen, komplexen Erkrankungen (n = 4) betroffen sind, wurden episodische Interviews geführt. Die Datenauswertung erfolgt mittels thematischen Kodierens.

Ergebnisse
Wenige Befragte meinen, durch Corona kaum persönlich gefährdet zu sein, so dass auch Schutzmaßnahmen wie Impfungen sekundär sind. Die meisten Interviewten jedoch berücksichtigen Schutzmaßnahmen penibel. Sie können sich hierzu entweder verpflichtet fühlen, um z. B. andere vulnerable Personen zu schützen, oder sie erleben sich als sehr anfällig für schwere Coronainfektionen. Ungeachtet von erlebten Einschränkungen im Lockdown ist dieser für viele Interviewte auch mit neuen Möglichkeiten verbunden. Online-Formate erleichtern ihnen, Studium/Ausbildung trotz chronischer Erkrankung fortzusetzen und Kontakte mit Freund*innen zu halten.

Schlussfolgerung
Coronarisikowahrnehmungen und Schutzverhalten junger chronisch kranker Erwachsener sollten in ihrem subjektiven Sinn verstärkt in der Versorgung und Begleitung dieser Zielgruppen berücksichtigt werden. Hybride Lehre sollte über den Lockdown hinaus beibehalten werden, damit die jungen Erwachsenen trotz ihrer chronischen Erkrankung sozial teilhaben können und zugleich vor Corona- und weiteren Infektionen geschützt sind.