bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alarmierung im Spital, eine technische Herausforderung
Authors: Ruh Emanuel 
Published: July 2023

ZusammenfassungAlarmsysteme sind ein unverzichtbarer Bestandteil der modernen Spitalinfrastruktur und gehören zum Lebensnerv eines Spitalbetriebs. Die Alarmsysteme helfen, Personal und Patienten vor Bedrohungen zu schützen und schnell auf Notfälle zu reagieren. Es gibt verschiedene Alarmsysteme in einem Spital, wie Notrufsysteme zur Unterstützung der Spitalprozesse (Rufanlagen, REA-Alarm, Notsectio), Medizinische Überwachung (Vitaldatenmonitoring, Telemetrie) und technische Überwachung (Brandmeldeanlagen, Gebäudeleitsysteme). In einer Gebärabteilung müssen medizinische Fachkräfte oft schnell auf kritische Situationen reagieren, um Leben zu retten oder gesundheitliche Schäden zu vermeiden. Eine schnelle und effektive Alarmierung ist daher von großer Bedeutung, um eine schnelle Reaktion zu gewährleisten. Die Systeme unterliegen diversen Normen und Vorgaben. Es ist auch wichtig, dass das Spital sicherstellt, dass die Alarmsysteme regelmäßig gewartet und aktualisiert werden, um sicherzustellen, dass sie bei Bedarf immer funktionieren. Schnittstelle und Alarmübertragung müssen so ausgeführt sein, dass eine sichere Übertragung von Alarmen gewährleistet ist. Alle Komponenten der Alarmkette müssen automatisch und end-to-end überwacht werden. Bei einem Ausfall des Systems müssen durch geeignete technische, personelle oder organisatorische Maßnahmen sichergestellt werden, dass die Überwachung von Patienten weiterhin erfolgen kann.
Development of cysteine-doped MnO2 quantum dots for spectrofluorimetric estimation of copper: applications in different matrices
Authors: Salman Baher I. , Hassan Ahmed I. , Saraya Roshdy E. , Ibrahim Adel Ehab , Mohammed Bassam Shaaban , Batakoushy Hany A. , El Deeb Sami , Hassan Yasser F. 
Published: July 2023

AbstractCopper (Cu) plays a role in maintaining healthy nerve cells and the immune system. Osteoporosis is a high-risk factor for Cu deficiency. In the proposed research, unique green, fluorescent cysteine-doped MnO2 quantum dots (Cys@MnO2 QDs) were synthesized and assessed for the determination of Cu in different food and hair samples. The developed quantum dots were synthesized with the help of cysteine using a straightforward ultrasonic approach to create 3D fluorescent Cys@MnO2 QDs. The resulting QDs’ morphological and optical characteristics were carefully characterized. By adding Cu ions, the intensity of fluorescence for the produced Cys@MnO2 QDs was found to be dramatically reduced. Additionally, the applicability of Cys@MnO2 QDs as a new luminous nanoprobe was found to be strengthened by the quenching effect grounded on the Cu–S bonding. The concentrations of Cu2+ ions were estimated within the range of 0.06 to 7.00 µg mL−1, with limit of quantitation equal to 33.33 ng mL−1 and detection limit equal to 10.97 ng mL−1. The Cys@MnO2 QD technique was applied successfully for the quantification of Cu in a variety of foods, including chicken meat, turkey, and tinned fish, as well as in human hair samples. The chance that this novel technique could be a useful tool for figuring out the amount of cysteine in bio-samples is increased by the sensing system’s remarkable advantages, which include being rapid, simple, and economical.
Graphical abstract
Does surgeon sex and anthropometry matter for tool usability in traditional laparoscopic surgery? A systematic review and meta-analysis
Authors: Hislop Jaime , Orth Dominic , Tirosh Oren , Isaksson Mats , Hensman Chris , McCormick John 
Published: July 2023

Abstract
Introduction
Hand size, strength, and stature all impact a surgeon’s ability to perform Traditional Laparoscopic Surgery (TLS) comfortably and effectively. This is due to limitations in instrument and operating room design. This article aims to review performance, pain, and tool usability data based on biological sex and anthropometry.

Methods
PubMed, Embase, and Cochrane databases were searched in May 2023. Retrieved articles were screened based on whether a full-text, English article was available in which original results were stratified by biological sex or physical proportions. Article quality was discussed using the Mixed Methods Appraisal Tool (MMAT). Data were summarized in three main themes: task performance, physical discomfort, and tool usability and fit. Task completion times, pain prevalence, and grip style results between male and female surgeons formed three meta-analyses.

Results
A total of 1354 articles were sourced, and 54 were deemed suitable for inclusion. The collated results showed that female participants, predominantly novices, took 2.6–30.1 s longer to perform standardized laparoscopic tasks. Female surgeons reported pain at double the frequency of their male colleagues. Female surgeons and those with a smaller glove size were consistently more likely to report difficulty and require modified (potentially suboptimal) grip techniques with standard laparoscopic tools.

Conclusions
The pain and stress reported by female or small-handed surgeons when using laparoscopic tools demonstrates the need for currently available instrument handles, including robotic hand controls, to become more size-inclusive. However, this study is limited by reporting bias and inconsistencies; furthermore, most data was collected in a simulated environment. Additional research into how anthropometric tool design impacts the live operating performance of experienced female surgeons would further inform this area of investigation.
Monitoring with verified guarantees
Authors: Baumeister Jan , Dauer Johann C. , Finkbeiner Bernd , Schirmer Sebastian 
Published: July 2023

AbstractRuntime monitoring is generally considered a light-weight alternative to formal verification. In safety-critical systems, however, the monitor itself is a critical component. For example, if the monitor is responsible for initiating emergency protocols, as proposed in a recent aviation standard, then the safety of the entire system critically depends on the correctness of the monitor. In this paper, we present a verification extension to theLolamonitoring language that extends the efficient specification of the monitor with Hoare-style annotations that guarantee the correctness of the monitor specification. We add two new operators, assume and assert, which specify assumptions of the monitor and expectations on its output, respectively. The validity of the annotations is established by an integratedSMTsolver. We report on experience in applying the approach to specifications from the avionics domain, where the annotation with assumptions and assertions has lead to the discovery of safety-critical errors in specifications. The errors range from incorrect default values in offset computations to complex algorithmic errors that result in unexpected temporal patterns. We also report how verified specifications can be monitored efficiently at runtime.
TRIP 13-dependent pathways promote the development of gastric cancer
Authors: Ni Fengming , Liu Xinmin , Xia Yan , Zhu He , Li Fudong , Zhang Nan , Xu Hong 
Published: July 2023

AbstractTRIP13 is highly expressed in various human tumors and promotes tumorigenesis. We aimed to explore the biological effect of TRIP13 on gastric cancer. The RNA sequence data were retrieved from TCGA to evaluate TRIP13 mRNA expression in gastric cancer. Paired formalin-fixed paraffin-embedded blocks were further analyzed to verify the relationship between TRIP13 expression and carcinogenic status. The functions of TRIP13 on the proliferation of gastric malignancy were investigated by MTT, flow cytometry, colony formation experiment, and nude mouse tumor formation experiment. Finally, microarray analysis of TRIP13-related pathways was performed to identify the potential underlying mechanism of TRIP13 in gastric cancer. TRIP13 was found to have high expression in tumor samples. TRIP13 expression status was significantly subjective to tumor-node-metastasis (TNM) staging and poor survival. The downregulation of TRIP13 promoted apoptosis and inhibited tumor growth. TRIP13-dependent JAK/STAT and NF-κB signaling cascade were found as two key pathways in the carcinogenesis of GC. In conclusion, TRIP13 participates in the carcinogenesis of stomach cancer, and its overexpression in the cancerous tissues dovetail with advanced stage and survival. Moreover, TRIP13 functions as an upstream regulator of the JAK/STAT and p53 signaling pathways, which play critical roles in developing various malignancies.
Data science and big data analytics: a systematic review of methodologies used in the supply chain and logistics research
Authors: Jahani Hamed , Jain Richa , Ivanov Dmitry 
Published: July 2023

AbstractData science and big data analytics (DS &BDA) methodologies and tools are used extensively in supply chains and logistics (SC &L). However, the existing insights are scattered over different literature sources and there is a lack of a structured and unbiased review methodology to systematise DS &BDA application areas in the SC &L comprehensively covering efficiency, resilience and sustainability paradigms. In this study, we first propose an unique systematic review methodology for the field of DS &BDA in SC &L. Second, we use the methodology proposed for a systematic literature review on DS &BDA techniques in the SC &L fields aiming at classifying the existing DS &BDA models/techniques employed, structuring their practical application areas, identifying the research gaps and potential future research directions. We analyse 364 publications which use a variety of DS &BDA-driven modelling methods for SC &L processes across different decision-making levels. Our analysis is triangulated across efficiency, resilience, and sustainability perspectives. The developed review methodology and proposed novel classifications and categorisations can be used by researchers and practitioners alike for a structured analysis and applications of DS &BDA in SC &L.
“We are Neither Commies nor Volunteers”: How National Culture Influences Professional Identity Construction of CSR Professionals in South Korea
Authors: Vu Mai Chi , Shin Hyemi , Burton Nicholas 
Published: July 2023

AbstractThis paper draws on an institutional logics perspective to illuminate a hitherto underexplored context for CSR professional identity construction. It draws on an empirical study of 65 CSR professionals in South Korea and aims to deepen our understanding of CSR professional identity construction by investigating the contested nature of the CSR professional field between, on the one hand, societal-normative expectations of the profession, and, in the absence of stable professional logics, CSR professionals’ desired professional identity, on the other. Our study reveals how CSR professionals engage with, and respond to, this complexity through constructing one of three distinctive professional identities based on different logic constellations. This process reveals a snapshot of professional logics ‘in-the-making’.
Short-chain fatty acids in cancer pathogenesis
Authors: Feitelson Mark A. , Arzumanyan Alla , Medhat Arvin , Spector Ira 
Published: July 2023

AbstractCancer is a multi-step process that can be viewed as a cellular and immunological shift away from homeostasis in response to selected infectious agents, mutations, diet, and environmental carcinogens. Homeostasis, which contributes importantly to the definition of “health,” is maintained, in part by the production of short-chain fatty acids (SCFAs), which are metabolites of specific gut bacteria. Alteration in the composition of gut bacteria, or dysbiosis, is often a major risk factor for some two dozen tumor types. Dysbiosis is often characterized by diminished levels of SCFAs in the stool, and the presence of a “leaky gut,” permitting the penetration of microbes and microbial derived molecules (e.g., lipopolysaccharides) through the gut wall, thereby triggering chronic inflammation. SCFAs attenuate inflammation by inhibiting the activation of nuclear factor kappa B, by decreasing the expression of pro-inflammatory cytokines such as tumor necrosis factor alpha, by stimulating the expression of anti-inflammatory cytokines such as interleukin-10 and transforming growth factor beta, and by promoting the differentiation of naïve T cells into T regulatory cells, which down-regulate immune responses by immunomodulation. SCFA function epigenetically by inhibiting selected histone acetyltransferases that alter the expression of multiple genes and the activity of many signaling pathways (e.g., Wnt, Hedgehog, Hippo, and Notch) that contribute to the pathogenesis of cancer. SCFAs block cancer stem cell proliferation, thereby potentially delaying or inhibiting cancer development or relapse by targeting genes and pathways that are mutated in tumors (e.g., epidermal growth factor receptor, hepatocyte growth factor, and MET) and by promoting the expression of tumor suppressors (e.g., by up-regulating PTEN and p53). When administered properly, SCFAs have many advantages compared to probiotic bacteria and fecal transplants. In carcinogenesis, SCFAs are toxic against tumor cells but not to surrounding tissue due to differences in their metabolic fate. Multiple hallmarks of cancer are also targets of SCFAs. These data suggest that SCFAs may re-establish homeostasis without overt toxicity and either delay or prevent the development of various tumor types.
One-step multiplex DiRT-PCR for PLRV, PVY, PVM, PVS, PVA and PVX ready for routine testing directly on tuber sap
Authors: Prinz Mirjam , Kellermann Adolf , Bauch Gerda 
Published: July 2023

AbstractPotato viruses PLRV, PVY, PVM, PVA, PVX and PVS can cause up to 90% loss of potato harvest. Therefore, they are monitored by law in many countries using DAS-ELISA or conventional real-time RT-qPCR. Previously, we developed a multiplex real-time DiRT-PCR (Direct reverse transcript – polymerase chain reaction), which works directly on diluted tuber sap and thus saves time and chemical processing for RNA extraction or time and space in the glasshouse. So far, this method only ran on sap of single tubers which is not practical for routine testing. We are now able to sensitively test for the presence of six viruses in two multiplex reactions using the real-time DiRT-PCR on pooled samples of ten tubers. Here we show that there is an “almost perfect” agreement (Gwet’s AC1 index) comparing this multiplex real-time DiRT-PCR on pooled samples with DAS-ELISA and a commercial RT-qPCR kit with a rapid extraction method. The multiplex real-time DiRT-PCR is now ready to be used for routine testing.
Lychaete pellucida as a novel biosorbent for the biodegradation of hazardous azo dyes
Authors: Khalaf Hussein A. , El-Sheekh Mostafa M. , Makhlof Mofida E. M. 
Published: July 2023

AbstractThe majority of textile wastes are made up of toxic dyes. Additionally, because these compounds are soluble, wastewater may include significant concentrations. In this work, the green alga Lychaete pellucida is used for the bioremoval of four common azo dyes, Reactive Blue 4 (RB4), Reactive Red 120 (RR120), Reactive Brilliant Yellow 3G (RBY3G), and Reactive Green12 (RG12), with the application of two models of sorption isotherms, Langmuir and Freundlich. The spectrophotometer method was used to identify optimum conditions (temperature, pH, dye concentrations, algal biomass, and contact time) to remove these dyes onto dry freshwater macroalgae. The optimum pH for L. pellucida was 8. The optimum biosorbent amount is 2 g/L. Then, the best-removed dye concentration was 5 mg/L, the optimum contact duration was 120 min, and the optimum temperature was 25 °C. Under optimum conditions, the percent of dye removal was about 95% for all used azo dyes. This is the first report on the use of Lychaete pellucida for the efficient biodegradation of hazardous azo dyes.
A Framework of Environmental, Personal, and Behavioral Factors of Adult Learning in Online Communities of Practice
Authors: Abedini Adam , Abedin Babak , Zowghi Didar 
Published: July 2023

Abstract
Adult learning is a complex phenomenon that takes place over an adult’s lifetime and is not limited to a particular age. It includes a set of activities to enhance life through improving skills, knowledge and capabilities. The foundational theories of adult learning, such as andragogy theory, place the individual adult centre stage and differentiate adult learning from formal learning. They also shift the focus from the individuals to the environment in which adult learning takes place. In line with this movement, online communities of practice (OCOPs) have evolved from being considered as online environments for learning to specialised forums that allow practitioners to collaborate around a project of mutual interest. The principles of adult learning are directly applicable to engagement in OCOPs because they include practical methods founded on the belief that adults are self-directed, autonomous learners and that learning is most effective when the environment plays the role of a facilitator, rather than being just a supportive and traditional setting for learning. However, how individual adults engage in OCOPs and benefit from them is not well understood. This paper draws on social cognitive theory to examine: how environmental, personal and behavioural factors shape engagement in OCOPs. To answer this question, twenty-one interviews were conducted with members of GitHub, a large online community of practice for IT professionals. The findings revealed that adults’ engagement in OCOPs involves project-based activities on mutual interests and willingness to help others. The findings also show that engaging in online communities does not only satisfy intrinsic, well-defined, expected outcomes and shape adults’ engagement, but also has an impact on adults’ lifelong learning achievements, such as professional experience and credit recognition. Based on these findings, a revised framework for adults’ engagement in OCOPs is presented and discussed.
Does official development assistance benefit the donor economy? New evidence from Japanese overseas infrastructure projects
Authors: Nishitateno Shuhei 
Published: July 2023

AbstractGiven the growing pressure on donors to curtail foreign aid budgets, analyzing the effectiveness of bilateral official development assistance (ODA) in realizing national interests has become more significant than ever. From the viewpoint of economic interests, prior research has revealed that ODA can help expand donor exports and outward foreign direct investments. This study is the first to provide evidence that ODA can also help firms from donor countries to win infrastructure projects in recipient countries. Employing unique contract data on Japanese overseas infrastructure projects, I estimate a fixed effects Poisson model with a panel dataset for 158 recipients for the period between 1970 and 2020. The results suggest that 17% of the total number of overseas infrastructure projects contracted to Japanese firms during 1970–2020 were attributable to Japanese ODA disbursement. I also explore the potential mechanism, finding that the Japanese ODA-infrastructure link is strengthened when Japanese loans and grants are simultaneously provided to a recipient country. This finding is consistent with the view that pre-investment studies conducted as part of technical cooperation could generate goodwill effects on Japanese firms during their bidding for Japanese yen loan projects.
Local search versus linear programming to detect monotonicity in simplicial branch and bound
Authors: Casado L. G. , G.-Tóth B. , Hendrix E. M. T. , Messine F. 
Published: July 2023

Abstract
This study focuses on exhaustive global optimization algorithms over a simplicial feasible set with simplicial partition sets. Bounds on the objective function value and its partial derivative are based on interval automatic differentiation over the interval hull of a simplex. A monotonicity test may be used to decide to either reject a simplicial partition set or to reduce its simplicial dimension to a relative border (at the boundary of the feasible set) facet (or face) by removing one (or more) vertices. A monotonicity test is more complicated for a simplicial sub-set than for a box, because its orientation does not coincide with the components of the gradient. However, one can focus on directional derivatives (DD). In a previous study, we focused on either basic directions, such as centroid to vertex or vertex to vertex directions, or finding the best directional derivative by solving an LP or MIP. The research question of this paper refers to using local search (LS) based sampling of directions from vertex to facet. Results show that most of the monotonic DD found by LP are also found by LS, but with much less computational cost. Notice that finding a monotone direction does not require to find the direction in which a derivative bound is the steepest.
The Communication Function of Universities: Is There a Place for Science Communication?
Authors: Entradas Marta , Bauer Martin W. , Marcinkowski Frank , Pellegrini Giuseppe 
Published: July 2023

AbstractThis article offers a view on the emerging practice of managing external relations of the modern university, and the role of science communication in this. With a representative sample of research universities in four countries, we seek to broaden our understanding of the science communication (SC) function and its niche within the modern university. We distinguish science communication from corporate communication functions and examine how they distribute across organisational levels. We find that communication functions can be represented along a spectrum of (de)centralisation: public relations and marketing activities are more likely carried out at the central level (central offices), and public affairs and SC activities are more likely carried out at decentral levels (e.g. in specific offices and/or research institutes, departments). This study shows that little attention is paid to science communication at central structures, suggesting that it is not a practice that aligns easily with university corporate communication, yet SC might find its niche increasingly in decentral locations of activity.
Hermite interpolation theorems for band-limited functions of the linear canonical transforms with equidistant samples
Authors: Annaby M. H. , Al-Abdi I. A. , Ghaleb A. F. , Abou-Dina M. S. 
Published: July 2023

AbstractWe establish convergence analysis for Hermite-type interpolations for$$L^{2} ( \mathbb {R})$$L2(R)-entire functions of exponential type whose linear canonical transforms (LCT) are compactly supported. The results bridges the theoretical gap in implementing the derivative sampling theorems for band-limited signals in the LCT domain. Both complex analysis and real analysis techniques are established to derive the convergence analysis. The truncation error is also investigated and rigorous estimates for it are given. Nevertheless, the convergence rate is$$O(1/\sqrt{N})$$O(1/N), which is slow. Consequently the work on regularization techniques is required.