bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterizing the thermal phase behaviour of fipronil polymorphs
Authors: Moyo Dennis Simbarashe , van der Merwe Elizabet Margaretha , Rademeyer Melanie , Malan Frederick Pieter , Atanasova Maria T. , Mapossa António Benjamim , Focke Walter Wilhelm 
Published: May 2023

AbstractThis manuscript reports the investigation of the polymorphic behaviour of fipronil using a systematic comparison of the thermochemical and structural properties of different crystal forms obtained in this study as well as those previously reported in literature. The analytical techniques employed include DSC, TGA, PXRD, SCXRD and hot stage microscopy. DSC proved particularly useful because it made it possible to differentiate between the two different crystal forms found in the as-received neat fipronil. The DSC scans revealed the presence of two polymorphs which had melting endotherms with peak maxima at ca. 196 °C and 205 °C, respectively. These polymorphs were successfully separated via sublimation and resulted in a metastable, lower melting polymorph in the sublimate and a thermodynamically stable, higher melting form in the sublimation residue. Clear evidence for the instability of the lower melting polymorph was found when the endotherms were examined under a range of heating rates. The proportion of the metastable form appeared to increase as the rate was increased, indicating that the metastable form underwent a solid–solid phase transition to the stable form at low heating rates. Recrystallization of fipronil from different solvents yielded five different forms. TGA curves revealed that all forms, except the acetone-derived one, were solvate pseudo-polymorphs that showed solvent loss between 60 and 100 °C. The acetone-derived sample was a hemihydrate that only started to show mass loss at 120 °C. SCXRD studies revealed that three of the five forms have similar structural characteristics, while the other two forms differ notably from each other and the rest of the structures. Despite these structural differences, all five forms exhibit near-identical intra- and intermolecular hydrogen bond networks.
Effects of cowpea (Vigna unguiculata) inoculation on nodule development and rhizosphere carbon and nitrogen content under simulated drought
Authors: Becker Joscha N. , Grozinger Janis , Sarkar Abhijit , Reinhold-Hurek Barbara , Eschenbach Annette 
Published: May 2023

Abstract
Aims
Inoculation with climate-adapted rhizobia is able to increase legume productivity in drought-prone regions of Sub-Saharan Africa. Enhanced nodulation might additionally affect plant-soil interactions and control rhizosphere carbon (C) and nitrogen (N) pools.

Methods
We investigated inoculation effects on nodulation and biological N2 fixation (BNF) of Vigna unguiculata and consequent effects on C and N pools in two Namibian soils. Three treatments (Bradyrhizobium sp.1–7 inoculant, non-inoculated, N-fertilised with 50 kg N ha−1) were applied in rhizoboxes at 45% and 20% maximum water holding capacity. Nodule development was photo-documented, and rhizobia-DNA sequences were identified. BNF was assessed by δ15N enrichment, and organic C and N pools were analysed in bulk and root adherent soil.

Results
Plant growth initially enhanced mineral N losses from the rhizosphere at flowering stage (6 weeks growth), but led to a re-increase of N, and organic C contents after ripening (10 weeks). Inoculation had no effect on nodulation and soil C and N pools, indicating that both soils contained sufficient indigenous rhizobia to allow effective nodulation. However, the inoculant strain was more competitive in establishing itself in the root nodules, depending on the local conditions, showing a need for regional adjustment of inoculation strategies.

Conclusion
Water stress was the main limitation for nodulation and, in combination with soil type, substantially affected rhizosphere and bulk soil C and N contents. The temporally enhanced rhizodeposition after ripening could be able to maintain soil C and N pools after legume cultivation.
Assessing students’ understanding of time concepts in Years 3 and 4: insights from the development and use of a one-to-one task-based interview
Authors: Thomas Margaret , Clarke Doug M. , McDonough Andrea , Clarkson Philip C. 
Published: May 2023

AbstractTime is an important but complex area of learning for students in the primary years. This study sought to develop a tool which would provide a clear picture of students’ understanding of what constitutes time and how time is related to clock and calendar use. Four major components of time, Awareness of time, Succession, Duration, and Measurement of time, with related key ideas, formed the basis for a Framework for the Learning and Teaching of Time. This Framework underpinned the development of a 69-item, one-to-one task-based interview to assess students’ understanding of time. Data from interviews of Year 3 and 4 students gave a clear picture of how they experienced the mathematics of time. The range of scores across all assessed areas of the Framework revealed a considerable spread of students’ understandings of time concepts. This paper focuses on the development of the Framework and interview, the interview data, and the general benefits of the use of the task-based assessment interview in assessing the mathematical understanding and thinking of children regarding time.
Heterogeneity of Autism Characteristics in Genetic Syndromes: Key Considerations for Assessment and Support
Authors: Jenner Lauren , Richards Caroline , Howard Rachel , Moss Joanna 
Published: May 2023

Abstract
Purpose of Review
Elevated prevalence of autism characteristics is reported in genetic syndromes associated with intellectual disability. This review summarises recent evidence on the behavioural heterogeneity of autism in the following syndromes: Fragile X, Cornelia de Lange, Williams, Prader-Willi, Angelman, Down, Smith-Magenis, and tuberous sclerosis complex. Key considerations for assessment and support are discussed.

Recent Findings
The profile and developmental trajectory of autism-related behaviour in these syndromes indicate some degree of syndrome specificity which may interact with broader behavioural phenotypes (e.g. hypersociability), intellectual disability, and mental health (e.g. anxiety). Genetic subtype and co-occurring epilepsy within syndromes contribute to increased significance of autism characteristics. Autism-related strengths and challenges are likely to be overlooked or misunderstood using existing screening/diagnostic tools and criteria, which lack sensitivity and specificity within these populations.

Summary
Autism characteristics are highly heterogeneous across genetic syndromes and often distinguishable from non-syndromic autism. Autism diagnostic assessment practices in this population should be tailored to specific syndromes. Service provisions must begin to prioritise needs-led support.
Strategies for Sustainable Production of Hydrogen Peroxide via Oxygen Reduction Reaction: From Catalyst Design to Device Setup
Authors: Tian Yuhui , Deng Daijie , Xu Li , Li Meng , Chen Hao , Wu Zhenzhen , Zhang Shanqing 
Published: May 2023

AbstractAn environmentally benign, sustainable, and cost-effective supply of H2O2 as a rapidly expanding consumption raw material is highly desired for chemical industries, medical treatment, and household disinfection. The electrocatalytic production route via electrochemical oxygen reduction reaction (ORR) offers a sustainable avenue for the on-site production of H2O2 from O2 and H2O. The most crucial and innovative part of such technology lies in the availability of suitable electrocatalysts that promote two-electron (2e–) ORR. In recent years, tremendous progress has been achieved in designing efficient, robust, and cost-effective catalyst materials, including noble metals and their alloys, metal-free carbon-based materials, single-atom catalysts, and molecular catalysts. Meanwhile, innovative cell designs have significantly advanced electrochemical applications at the industrial level. This review summarizes fundamental basics and recent advances in H2O2 production via 2e–-ORR, including catalyst design, mechanistic explorations, theoretical computations, experimental evaluations, and electrochemical cell designs. Perspectives on addressing remaining challenges are also presented with an emphasis on the large-scale synthesis of H2O2 via the electrochemical route.
A Review on Interface Engineering of MXenes for Perovskite Solar Cells
Authors: Palei Srikanta , Murali G. , Kim Choong-Hee , In Insik , Lee Seul-Yi , Park Soo-Jin 
Published: May 2023

AbstractWith an excellent power conversion efficiency of 25.7%, closer to the Shockley–Queisser limit, perovskite solar cells (PSCs) have become a strong candidate for a next-generation energy harvester. However, the lack of stability and reliability in PSCs remained challenging for commercialization. Strategies, such as interfacial and structural engineering, have a more critical influence on enhanced performance. MXenes, two-dimensional materials, have emerged as promising materials in solar cell applications due to their metallic electrical conductivity, high carrier mobility, excellent optical transparency, wide tunable work function, and superior mechanical properties. Owing to different choices of transition elements and surface-terminating functional groups, MXenes possess the feature of tuning the work function, which is an essential metric for band energy alignment between the absorber layer and the charge transport layers for charge carrier extraction and collection in PSCs. Furthermore, adopting MXenes to their respective components helps reduce the interfacial recombination resistance and provides smooth charge transfer paths, leading to enhanced conductivity and operational stability of PSCs. This review paper aims to provide an overview of the applications of MXenes as components, classified according to their roles as additives (into the perovskite absorber layer, charge transport layers, and electrodes) and themselves alone or as interfacial layers, and their significant importance in PSCs in terms of device performance and stability. Lastly, we discuss the present research status and future directions toward its use in PSCs.
Microstructure and properties of AlCr and AlCrFe coatings deposited by magnetron sputtering
Authors: Ura-Bińczyk Ewa , Kulikowski Krzysztof , Chromiński Witold , Smolik Jerzy , Lewandowska Małgorzata 
Published: May 2023

Abstract
In this work, AlCr and AlCrFe coatings were deposited via magnetron sputtering on technical substrates of carbon steel C45 and titanium grade 2. The coatings feature an amorphous structure, a thickness of 3–4 μm, and are uniform in terms of thickness and chemical composition. No major defects were visible at the interface; however, there is no diffusion at the interface, which indicates the adhesive type of bonding and results in relatively low adhesion. The coatings are characterized by a hardness of about 8–10 GPa and a Young modulus above 150 GPa. Both values are slightly higher for steel substrate. The coatings assure good corrosion resistance for steel substrate while underperforming those of Ti grade 2.
Application of a 3D hydrogel-based model to replace use of animals for passaging patient-derived xenografts
Authors: Jones Sal , Ashworth Jennifer C. , Meakin Marian , Collier Pamela , Probert Catherine , Ritchie Alison A. , Merry Catherine L. R. , Grabowska Anna M. 
Published: May 2023

Abstract
Purpose
This 3D in vitro cancer model for propagation of patient-derived cells, using a synthetic self-assembling peptide gel, allows the formation of a fully characterised, tailorable tumour microenvironment. Unlike many existing 3D cancer models, the peptide gel is inert, apart from molecules and motifs deliberately added or produced by cells within the model.

Methods
Breast cancer patient-derived xenografts (PDXs) were disaggregated and embedded in a peptide hydrogel. Growth was monitored by microscopic examination and at intervals, cells were extracted from the gels and passaged on into fresh gels. Passaged cells were assessed by qPCR and immunostaining techniques for the retention of characteristic markers.

Results
Breast cancer PDXs were shown to be capable of expansion over four or more passages in the peptide gel. Contaminating mouse cells were found to be rapidly removed by successive passages. The resulting human cells were shown to be compatible with a range of common assays useful for assessing survival, growth and maintenance of heterogeneity.

Conclusions
Based on these findings, the hydrogel has the potential to provide an effective and practical breast cancer model for the passage of PDXs which will have the added benefits of being relatively cheap, fully-defined and free from the use of animals or animal products. Encapsulated cells will require further validation to confirm the maintenance of cell heterogeneity, genotypes and phenotypes across passage, but with further development, including the addition of bespoke cell and matrix components of the tumour microenvironment, there is clear potential to model other cancer types.
Enhancing the Anthropocene coastal infrastructure sustainability using the approaches developed by the London Convention and Protocol
Authors: Hong GiHoon , Vivian Christopher , Vogt Craig , Haag Fredrik , Zuo Fang , Qin Kai 
Published: May 2023

AbstractThe water’s edge is a critically important and efficient location to trade with other partners by connecting inland water channels and sea lanes and to obtain food provisions from the biologically diverse and productive sea. Human civilization has built around the ports and harbors by constructing fixed structures to support waterborne transport and enhance or sustain city functions for millennia. These artificially fixed structures are not in natural equilibrium with the environment (water and sediment). Access channels and the sea bottom adjacent to piers are often dredged to accommodate larger ships. Bottom sediment dredging is a part of port management. Where to place the dredged material is of primary concern for port authorities because of its sheer volume and the potential to be chemically contaminated. The London Convention and the London Protocol (LC/LP) are international treaties that provide a process in preventing pollution from dumping of contaminated material at sea, and finding sound alternatives such as confined disposal facilities, and using clean dredged material in wetland creation or beach nourishment, based on the precautionary approach. The Anthropocene (Anthropocene refers to the most recent period in Earth’s history when human activity started to impact significantly on the climate and ecosystems.) coast of ports, harbors, wetlands, shorelines, and beaches of the coastal megacities faces tremendous challenges in managing navigational and shoreline infrastructure in view of sea level rise and climate change. Dredged sediments are a resource and are a key to protection of shorelines. The benefits of being members of the LC/LP treaties are that there is a wealth of various national experiences on sediment management available via the network of LC/LP national experts and in the records of the LC/LP’s Meetings of Contracting Parties.
Citrus growers’ willingness to pay and perceptions of cover crops
Authors: Cosgray Carter , Chakravarty Shourish , Wade Tara , Gao Zhifeng 
Published: May 2023

AbstractThis study develops and uses a survey to gather information on demographics, production and management practices, and perceptions on using cover crops as a conservation practice from citrus growers and utilizes the double-bounded dichotomous choice contingent valuation method to measure their willingness to pay (WTP) for adopting cover crops in citrus production. The survey is conducted for citrus producers in Florida and Texas. The study finds that, on average, growers from Florida are willing to pay $509.48/acre per year for adopting cover crops. This is substantially less than the WTP for growers in Texas, who are willing to pay more than $1,000/acre per year for cover crops. The study analyzes the factors that have significant impacts on growers’ WTP for cover crops and discusses the heterogeneity in the grower perceptions on the benefits and drawbacks of using this conservation practice by state. Although using cover crops has not been a popular conservation practice in perennial fruit production systems, its potential to improve soil quality is particularly important for citrus production in Florida where soils are sandy and have low organic matter.
On asymptotic fairness in voting with greedy sampling
Authors: Gutierrez Abraham , Müller Sebastian , Šebek Stjepan 
Published: May 2023

AbstractThe basic idea of voting protocols is that nodes query a sample of other nodes and adjust their own opinion throughout several rounds based on the proportion of the sampled opinions. In the classic model, it is assumed that all nodes have the same weight. We study voting protocols for heterogeneous weights with respect to fairness. A voting protocol is fair if the influence on the eventual outcome of a given participant is linear in its weight. Previous work used sampling with replacement to construct a fair voting scheme. However, it was shown that using greedy sampling, i.e., sampling with replacement until a given number of distinct elements is chosen, turns out to be more robust and performant.In this paper, we study fairness of voting protocols with greedy sampling and propose a voting scheme that is asymptotically fair for a broad class of weight distributions. We complement our theoretical findings with numerical results and present several open questions and conjectures.
Impact of the COVID-19 pandemic on CTSA Clinical Research Centers over 2 years
Authors: Samuels Mary H. , Hommeyer Ella , Booty Brian , Frost Kelli , Morris Cynthia 
Published: May 2023

Abstract

Introduction:
The COVID-19 pandemic had an abrupt impact on patient-oriented research early in the pandemic. CTSA Clinical Research Centers (CRCs) rapidly adapted to this challenge, but the continued impact of later phases of the pandemic on CRC operations is not clear.

Methods:
An online REDCap survey of CTSA CRCs was developed that covered the first 2 years of the pandemic. The survey focused on impact on CRC functions, mitigation strategies, recovery of CRC activities, CRC contributions to COVID-related research, and potential lessons for future public health emergencies. The survey was sent to CRC directors at 61 CTSA Hubs in May 2022.

Results:
Twenty-seven Hubs (44%) responded to the survey. Most CRCs reported greater than 50% declines in inpatient census in the first year of the pandemic, with less severe impacts on outpatient census. CRCs pivoted to support COVID-related research and adopted innovative technology-driven approaches to support clinical research. Census improved in the second year of the pandemic in most CRCs but often remained below pre-pandemic levels, and greater than half of CRCs reported decreased revenue.

Conclusions:
CTSA-supported CRCs faced unprecedented challenges at the onset of the COVID-19 pandemic and responded rapidly to support COVID-related research and implement innovative approaches that allowed patient-oriented research activities to resume. However, many CRCs continued to report decreased research activities in the second year of the pandemic, and the long-term effects on CRC operations on finances are not clear. CRCs will likely need to evolve to provide support in nontraditional ways.
Dual role of glycans and binding receptors in pathogenesis of enveloped viruses (by mainly focusing on two recent pandemics)
Authors: Pourrajab Fatemeh , Zare-Khormizi Mohamad Reza 
Published: May 2023

Abstract
A period of about a decade has been estimated to pass for the emergence of a new infectious strain of a virus that may lead to the occurrence of a pandemic one. It is now suggested that the variants of the 1918 H1N1 and coronavirus disease-19 pandemics could have existed in humans after the initial cross-species introduction to humans and underwent multiple low-level seasonal epidemics before the occurrence of their outbreaks. They share similarities in the continuation, widespreadness due to high transmissibility, high fatality rate and clinical symptoms. They are assumed to share a similar principle of a zoonotic source and a cross-species pathway for transmission. They show some similarities in their pathogenesis with other enveloped viruses: Severe Acute Respiratory Syndrome Coronavirus-1 (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), human immunodeficiency virus, Ebola, Lassa and measles viruses. The highly pathogenic nature of these viruses and their genetic variants may depend on their binding affinity for host cell receptors, whereby they efficiently circumvent or block host cell immune responses triggered by cytokines (interferon). High transmission rates and viral pathogenicity are attributed to glycan moieties that facilitate virus binding to host multiple receptors and cell entry, thereby helping viruses to evade immune recognition and response. Also, mucosa glycotopes are a matter of concern that play as primary sites for virus attachment and body entry. Finding general lectins or ligands that block the viral–host receptors interaction or identifying individual glycotopes is the therapeutic and prognosis topic that demands the main focus.
Systematic Review on Quality Indicators of Randomised Controlled Trial Reading Intervention Studies for Students in Years 7–12
Authors: Calvi Michael , Vieira Ana Paula Alves , Georgiou George , Parrila Rauno 
Published: May 2023

AbstractA number of studies have examined the effects of reading interventions for younger readers; however, there does not appear to be any existing syntheses examining the effect of reading interventions on students in Years 7–12. The purpose of this study was to establish whether such a synthesis is feasible by reviewing the methodological quality of randomised controlled trial studies examining the effect of reading interventions for secondary students, using the Council for Exceptional Children (CEC) standards. A total of 17 studies were identified and reviewed. Overall, only two studies met all eight CEC quality indicators. All studies met the quality indicators for intervention agent, and context and settings. Findings, limitations and recommendations for future directions of study are discussed.
The politics of anti-plastics activism in Indonesia and Malaysia
Authors: Dauvergne Peter , Islam Saima 
Published: May 2023

AbstractResearch on anti-plastics activism in Indonesia and Malaysia, although increasing somewhat in recent years, is sparse and patchy. Interviews with local activists and a review of the existing literature, however, does suggest this activism is intensifying. Activists are educating people of the health and ecological risks of plastics, and operating nonprofit organizations to recycle and repurpose plastics. They are organizing cleanups and advocating for marginalized waste workers. And they are lobbying governments for stricter regulations, exposing illegal operations, and building transnational advocacy networks. Collectively, these strands of activism appear to have the potential to aggregate eco-actions and decrease plastic pollution. In the coming years, however, given the power of the global plastics industry and the nature of politics within Indonesia and Malaysia, pro-plastics corporations and industry allies are likely going to increasingly contest anti-plastics narratives and strive to undermine efforts to address the root causes of plastic pollution, including rising sales of single-use plastics by transnational corporations, the dumping and burning of unrecyclable plastics from high-income countries, and inadequate waste infrastructure and regulatory enforcement. Further research on how this politics is affecting the power and effectiveness of anti-plastics activism, the article concludes, is going to be essential for improving plastics governance.