bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustained Lumen Area by Paclitaxel-Coated Balloon Following Rotational Atherectomy for Napkin-Ring Left Main Trunk Ostial Lesion
Authors: Osawa Takumi , Koizumi Tomomi , Ito Yuta 
Published: March 2023

Abstract
Late lumen enlargement after percutaneous coronary intervention (PCI) with drug-coated balloon has contributed to good clinical results. However, late lumen enlargement with drug-coated balloon following rotational atherectomy has not been well reported. This report describes a case of calcified napkin-ring ostial lesion at the left main trunk that showed a sustained lumen area after PCI with drug-coated balloon following rotational atherectomy. An 85-year-old female patient was admitted to the hospital with dyspnea. Echocardiography showed hypokinesis in the anteroseptal and inferior walls. Electrocardiograph-gated cardiac computed tomography showed a calcified ostial lesion in the left main trunk. Invasive angiography of the coronary artery showed severe stenosis in the left main trunk ostium. Percutaneous coronary intervention was performed with a drug-coated balloon after rotational atherectomy. The minimal lumen area measured by intravascular ultrasound grew mildly from 4.09 to 4.17 mm2 immediately after PCI. Follow-up angiography and intravascular ultrasound performed after 6 months showed that the minimal lumen area in the left main trunk ostium was further enlarged from 4.17 to 4.69 mm2. The presence of sustained lumen area after PCI with drug-coated balloon following rotational atherectomy for a napkin-ring left main trunk ostial lesion was confirmed. This case demonstrates sustained lumen area after drug-coated balloon following rotational atherectomy in the left main trunk ostium, improving the patient's chest symptom. Hence, drug-coated balloon after rotational atherectomy may be an option for complex stent sites, such as the left main trunk ostium in geriatric patients and sites with highly calcified lesions.
Enhanced Left Ventricular Recovery in Treatment of Mitral Regurgitation With Severe Left Ventricular Dysfunction
Authors: Devich Robert , Mahesh Balakrishnan , Bhat Geetha , Kozak Mark , Choi Esther , Melton Nathaniel , Dowling Robert 
Published: March 2023

Abstract
A 73-year-old male patient presented with shortness of breath at rest resulting from new-onset severe primary mitral regurgitation with a flail posterior leaflet, left ventricular dysfunction, and cardiogenic shock. After initial stabilization in the intensive care unit, multiple treatment options were considered for this patient, all associated with significant mortality. Ultimately, operative mitral valve repair with Impella 5.5 placement was performed for postoperative hemodynamic support. Surgical repair provided elimination of mitral regurgitation. Impella support was maintained for 7 days to provide unloading of the left ventricle. After device removal, the patient had sustained left ventricular recovery with significantly improved ejection fraction. Full left ventricular support and unloading may decrease operative risk and promote left ventricular recovery in patients with severe mitral regurgitation and left ventricular dysfunction. This case emphasizes the value of ventricular unloading to facilitate the recovery of left ventricular function as a treatment option for patients with challenging cases of severe mitral regurgitation and left ventricular dysfunction.
Short‐term repeated sprint training in hypoxia improves explosive power production capacity and repeated sprint ability in Japanese international‐level male fencers: A case study
Authors: Hagiwara Masahiro , Yamagishi Takaki , Okamoto Shogo , Azuma Yasuyuki , Yamashita Daichi 
Published: March 2023

AbstractThis case study reports the effects of six sessions of repeated sprint training in hypoxia (RSH) over 3 weeks on explosive power production capacity and repeated sprint ability (RSA) in two Japanese international‐level foil fencers. The six RSH sessions (60‐s sprints in total per session: consisting of two sets of five 6‐s sprints with 30‐s passive recovery, at simulated altitude of 3000 m) caused improvements of peak power output (PPO; Athlete A: 5.1%; Athlete B: 3.2%) and mean power output (MPO; Athlete A: 4.4%; Athlete B: 1.6%) over the 10 repeated sprints, respectively. The observed findings suggest that as few as six RSH sessions over 3 weeks can improve, at least to some extent, explosive power production capacity (PPO) and RSA (MPO) in the two elite fencers. To the best of our knowledge, this is the first study to apply short‐term RSH in combat sport (fencing) with international‐level athletes. Further studies are required to explore the effectiveness of short‐term RSH in combat sports with a more robust study design (e.g., randomized control trial with adequate statistical power) as the modality of RSH would suit physical and physiological demands in the majority of combat sports (e.g., wrestling, boxing).
Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
Authors: Kasperek Mikaela C. , Mailing Lucy , Piccolo Brian D. , Moody Becky , Lan Renny , Gao Xiaotian , Hernandez‐Saavedra Diego , Woods Jeffrey A. , Adams Sean H. , Allen Jacob M. 
Published: March 2023

AbstractRegular, moderate exercise modifies the gut microbiome and contributes to human metabolic and immune health. The microbiome may exert influence on host physiology through the microbial production and modification of metabolites (xenometabolites); however, this has not been extensively explored. We hypothesized that 6 weeks of supervised, aerobic exercise 3×/week (60%–75% heart rate reserve [HRR], 30–60 min) in previously sedentary, lean (n = 14) and obese (n = 10) adults would modify both the fecal and serum xenometabolome. Serum and fecal samples were collected pre‐ and post‐6 week intervention and analyzed by liquid chromatography/tandem mass spectrometry (LC–MS/MS). Linear mixed models (LMMs) identified multiple fecal and serum xenometabolites responsive to exercise training. Further cluster and pathway analysis revealed that the most prominent xenometabolic shifts occurred within aromatic amino acid (ArAA) metabolic pathways. Fecal and serum ArAA derivatives correlated with body composition (lean mass), markers of insulin sensitivity (insulin, HOMA‐IR) and cardiorespiratory fitness (), both at baseline and in response to exercise training. Two serum aromatic microbial‐derived amino acid metabolites that were upregulated following the exercise intervention, indole‐3‐lactic acid (ILA: fold change: 1.2, FDR p < 0.05) and 4‐hydroxyphenyllactic acid (4‐HPLA: fold change: 1.3, FDR p < 0.05), share metabolic pathways within the microbiota and were associated with body composition and markers of insulin sensitivity at baseline and in response to training. These data provide evidence of physiologically relevant shifts in microbial metabolism that occur in response to exercise training, and reinforce the view that host metabolic health influences gut microbiota population and function. Future studies should consider the microbiome and xenometabolome when investigating the health benefits of exercise.
Sex and strain differences in renal hemodynamics in mice
Authors: Tao Yu , Young‐Stubbs Cassandra , Yazdizadeh Shotorbani Parisa , Su Dong‐Ming , Mathis Keisa W. , Ma Rong 
Published: March 2023

AbstractThe present study was to examine sex and strain differences in glomerular filtration rate (GFR) and renal blood flow (RBF) in C57BL6, 129/Sv, and C57BLKS/J mice, three commonly used mouse strains in renal research. GFR was measured by transdermal measurement of FITC‐sinitrin clearance in conscious mice. RBF was measured by a flow probe placed in the renal artery under an anesthetic state. In C57BL6 mice, there were no sex differences in both GFR and RBF. In 129/Sv mice, females had significantly greater GFR than males at age of 24 weeks, but not at 8 weeks. However, males had higher RBF and lower renal vascular resistance (RVR). Similar to 129/Sv, female C57BLKS/J had significantly greater GFR at both 8 and 24 weeks, lower RBF, and higher RVR than males. Across strains, male 129/Sv had lower GFR and higher RBF than male C57BL6, but no significant difference in GFR and greater RBF than male C57BLKS/J. No significant difference in GFR or RBF was observed between C57BL6 and C57BLKS/J mice. Deletion of eNOS in C57BLKS/J mice reduced GFR in both sexes, but decreased RBF in males. Furthermore, there were no sex differences in the severity of renal injury in eNOS−/− dbdb mice. Taken together, our study suggests that sex differences in renal hemodynamics in mice are strain and age dependent. eNOS was not involved in the sex differences in GFR, but in RBF. Furthermore, the sexual dimorphism did not impact the severity of renal injury in diabetic nephropathy.
Prenatal genetic diagnosis of monogenic diseases
Authors: Prior-de Castro Carmen , Gómez-González Clara , Rodríguez-López Raquel , Macher Hada C. 
Published: March 2023

Abstract
Prenatal genetic diagnosis of monogenic diseases is a process involving the use of a variety of molecular techniques for the molecular characterization of a potential monogenic disease in the fetus during pregnancy. Prenatal genetic diagnosis can be performed through invasive and non-invasive methods. A distinction must be made between “NIPD” (non-invasive prenatal diagnosis), which is considered to be diagnostic, from “NIPT” (non-invasive prenatal test), which is a screening test that requires subsequent confirmation by invasive methods. The different techniques currently available aim at detecting either, previously characterized pathogenic mutations in the family, the risk haplotype associated with the familial mutation, or potential pathogenic mutation(s) in a gene associated with a diagnostic suspicion. An overview is provided of relevant aspects of prenatal genetic diagnosis of monogenic diseases. The objective of this paper is to describe the main molecular techniques currently available and used in clinical practice. A description is provided of the indications, limitations and analytical recommendations regarding these techniques, and the standards governing genetic counseling. Continuous rapid advances in the clinical applications of genomics have provided increased access to comprehensive molecular characterization. Laboratories are struggling to keep in pace with technology developments.
Same or different? Subject realization in the majority and the heritage language of Polish-German bilingual children
Authors: Brehmer Bernhard , Sopata Aldona , Canzi Massimiliano 
Published: March 2023

Abstract
The paper examines the extent to which bilingual children select lexical noun phrases and null and overt pronouns as referring expressions in their majority language German and their heritage language Polish. Both languages are similar regarding the availability of lexical noun phrases but differ in terms of the distribution of null and overt pronominal forms. Our focus lies on discourse contexts with a subject antecedent in the preceding clause, which require only light processing for both speaker and hearer due to the high accessibility of the intended subject referent. Drawing on experimental data from a picture story retelling task (MAIN) to investigate the distribution of referring expressions in the two languages compared to age-matched monolingual control groups, our results reveal that bilingual children are sensitive to crosslinguistic differences in the syntactic and discourse-pragmatic constraints that regulate the distribution of null and overt subjects in Polish and German, depending on the mode of speech (narrative or dialogic). Furthermore, there are no significant differences between the bilingual and monolingual children, irrespective of language and age group. Thus, our study cannot confirm findings of previous studies concerning the tendency of bilingual children to be either overspecific or underspecific in subject reference production.
Trophic niche overlap among Neotropical carnivores in a silvicultural landscape
Authors: de Almeida Ana Beatriz , Magioli Marcelo , Gheler-Costa Carla , Verdade Luciano Martins , Marques Thiago Simon , de Cássia Gilli de Lima Letícia , Püttker Thomas 
Published: March 2023

Abstract
To enable long-term coexistence, species need to differentiate at least one of the three main dimensions of the ecological niche (temporal, spatial, or trophic dimension). Here, we investigated whether mammalian predators (Chrysocyon brachyurus, Cerdocyon thous, Lycalopex vetulus, and Puma concolor) follow the prediction of trophic niche partitioning, which is expected when partitioning of food resources represents an important mechanism for coexistence. We predicted low niche overlap in general and low between P. concolor and the other species. We analyzed 207 fecal samples collected at a landscape composed of forest remnants immersed in Eucalyptus plantations. Food items (animals and plants) were identified using exoskeletons, feathers, scales, teeth, hair, and seeds. We calculated the frequency and percentage of occurrence of food items, niche breadth, and niche overlap between pairs of species. Prey size was similar among all predators, consuming mainly small-sized prey (<1 kg). However, niche breadth was larger for smaller carnivores compared to larger ones. No species pair showed significantly lower niche overlap than expected by chance. Our study provided detailed information on trophic resource use of sympatric carnivores, showing that trophic niche partitioning seems not to be crucial for the coexistence of carnivores in the study area.
Electrically switchable and tunable infrared light modulator based on functional graphene metasurface
Authors: Luo Wei , Abbasi Syeda Aimen , Zhu Shaodi , Li Xuejin , Ho Ho-Pui , Yuan Wu 
Published: March 2023

Abstract
Graphene is emerging as an ideal material for new-generation optoelectronic devices. In this paper, a novel graphene metasurface-based electrically switchable and tunable infrared light modulator has been proposed and theoretically studied. The functional modulator comprises a monolayer graphene sheet sandwiched in a Fabry–Perot (FP) like nanostructure consisting of a metal reflector, a dielectric spacer, and an ellipse patterned anisotropy antenna layer. As a result of the photon localization effect of the guided-mode resonance (GMR) in the FP structure, the graphene electroabsorption can be significantly enhanced to enable a high-performance light modulator. By fine-tuning the Fermi energy (E
f) of graphene via controlling its bias-gate voltage, the proposed modulator can switch between a perfect absorber and a reflective polarization converter of high conversion efficiency (i.e., >90%) at 1550 nm. The conversion mechanism and the geometric dependences of the infrared light modulator have been investigated. We further demonstrated the tunability of the highly-efficient polarization converter over a broad spectrum by adjusting the real dispersion of E
f. Our design concept provides an effective strategy for customizing novel optoelectronic devices by combining an electrically-tunable 2D material with a functional metasurface.
Comparative study of the photocatalytic degradation of tetracycline under visible light irradiation using Bi24O31Br11-anchored carbonaceous and silicates catalyst support
Authors: Sanni Saheed O. , Akpotu Samson O. , Pholosi Agnes , Pakade Vusumzi E. 
Published: March 2023

Abstract
This study compared two hydrothermally synthesized heterojunctions composites, Bi24O31Br10 – carbonaceous (activated carbon from zinc chloride [ACZ], phosphoric acid [ACH], carbonized material [CM]), and Bi24O31Br10 – silicates (SBA-15 and MCM-41), with nanosheets structure. The photocatalytic degradation
of tetracycline (TC) was used to evaluate the synergistic influence of the catalyst supports for the corresponding heterojunction composites. The X-Ray diffractometry (XRD), Fourier transform infrared spectroscopy and scanning electron microscopy (SEM) confirmed the synthesis of the Bi24O31Br10 (BOB) – composites. After 120 min of visible LED light photocatalytic reactions, the degradation trend in removal efficiency of TC was BOB-ACZ > BOB > ACH > BOB-CM > BOB-MCM-41 > BOB-SBA-15 > BOB. The study reveals that Bi24O31Br11 – carbonaceous composite exhibits much better degradation efficiency than Bi24O31Br11 – silicates. Crucially, the synergistic surface interaction of ACZ with BOB, and the efficient separation of photogenerated charge carriers, from the SEM, XRD analysis, and photocurrent response, confirmed the photocatalytic enhancement of the heterojunction formation of the BOB-ACZ composite. This study further provides convincing insights on the superiority of carbonaceous nanomaterial to silica materials as efficient catalyst support in catalytic applications.
Grafting of heavy metal oxides onto pure polyester for the interest of enhancing radiation shielding performance
Authors: Yasmin Sabina , Almousa Nouf , Abualsayed Mohammad I. , Elsafi Mohamed 
Published: March 2023

Abstract
In the interest of obtaining new polyester, heavy metal oxides PbCO3, Bi2O3, and CdO with numerous ratios have been added to the polyester resin. Five samples of labeled PR-1, PR-2, PR-3, PR-4, and PR-5 were prepared for this study. The values of linear attenuation coefficients (LAC) of the new polyester samples were measured using an HPGe detector. In the interest of ensuring the experimental setup, the value of LAC obtained from the HPGe detector as well as the value of LAC calculated using Phy-X software, have both been placed in one graph, which revealed a consistent result. The experimental value of those new polyester samples has been measured within the energy region 0.06–1.332 MeV, whereas the theoretical values have been calculated within the energy limit of 0.015–15 MeV. The results of all the new polyester samples showed an uplifting trend according to the rising energy at 0.06, 0.66, 1.17, and 1.33 MeV. At energy 0.06 MeV, sample PR-5 (ρ = 2.180 g/cm3) showed the lowest half value layer (HVL) among the polyester samples. This result is due to the addition of Bi2O3 and CdO into the samples’ composition, increasing their density and enhancing the polyester’s reduction ability. Considering the measured shielding parameters studied herein, it has been found that sample PR-5 (50 wt% Polymer resin, 25 wt% Bi2O3, 25 wt% CdO) had the highest shielding ability compared with the rest of the polyester samples.
Präsent bleiben
Authors: Haußmann Annette 
Published: March 2023

Zusammenfassung
Präsenz ist als ein Dasein und Mitgehen die wichtigste Grundlage für Seelsorge und Spiritual Care. Durch die Pandemie wurde ein Digitalisierungsschub ausgelöst, der sich bis heute in verschiedenen Bereichen der kirchlichen Arbeit niederschlägt, denn es mussten Alternativen zur leiblichen Begegnung gesucht werden. Eine empirische Studie während des zweiten Lockdowns untersucht Seelsorgende in Deutschland und befragt sie hinsichtlich ihrer seelsorglichen Mediennutzung, ihrer Einstellungen zur digitalen Kommunikation und leiblichen Präsenz sowie zu seelsorglichen Innovationen. Die Ergebnisse zeigen, dass immer noch das leiblich-präsente Gespräch am häufigsten stattfindet, aber auch die Kommunikation per Brief, Telefon und Videochat deutlich angestiegen ist. Überwiegend sind die Seelsorgenden positiv gegenüber digitaler Kommunikation eingestellt und beurteilen differenzsensibel deren mögliche seelsorgliche Nutzung abhängig von Zielgruppen und Situationen, schätzen die leibliche Interaktion aber zugleich als unverzichtbar ein. Hier findet sich eine Diskrepanz zwischen grundsätzlicher Befürwortung von Digitalisierung im Rahmen von Seelsorge gegenüber ihrer tatsächlichen Nutzung. So bedienen sich Seelsorgende mehrheitlich traditioneller Medien wie Brief oder Telefon und bieten leibliche Präsenz in kreativer Gestalt an. Digitale seelsorgliche Innovationen einschließlich eines blended setting sind demgegenüber unterrepräsentiert. Eine präsente Seelsorge – digital und/oder leiblich – ist alternativlos. Mediale und digitale Möglichkeiten für eine zukunftsorientierte Seelsorge sind bei weitem noch nicht ausgeschöpft.
Investigation of the Tensile Properties in Continuous Glass Fiber–Reinforced Thermoplastic Composite Developed Using Fused Filament Fabrication
Authors: Shah Jaydeep R. , Thanki Shashank 
Published: March 2023

Abstract
Continuous fiber–reinforced thermoplastic composites are gaining acceptance in the manufacturing sector. However, the production constraints of intricate designs, the difficulty of using unique fiber alignment, and the expensive moldings make their usage inadequate. This investigation attempts to produce composites using continuous glass fiber as filler material and three distinct polymers, acrylonitrile butadiene styrene, polylactic acid, and polyethylene terephthalate glycol, utilizing an indigenously built nozzle attachment with the fused filament fabrication (FFF) process. Furthermore, scanning electron microscopy (SEM) images were used to elucidate the interface performance. The experimental results showed that the tensile strength of glass fiber–reinforced composites was 218 to 241 % greater than that of just thermoplastic specimens when the printing raster direction was 0° and 35 to 45 % lower when the printing raster orientation was 90°. Furthermore, SEM findings revealed that the tensile stress was very low and had bad interface behavior when the printing raster orientation was 90°. FFF has more adaptability for fiber reinforcement because of its meticulous orientation and good dispersal capabilities for the additively manufactured part, which may be directly used as the final product. The fiber content and its interfacing with base material are critical technical specifications for the composites.
Neighborhood Opportunity and Mortality Among Children and Adults in Their Households
Authors: Slopen Natalie , Cosgrove Candace , Acevedo-Garcia Dolores , Hatzenbuehler Mark L. , Shonkoff Jack P. , Noelke Clemens 
Published: March 2023

BACKGROUND AND OBJECTIVES
Research has linked neighborhood opportunity to health outcomes in children and adults; however, few studies have examined neighborhood opportunity and mortality risk among children and their caregivers. The objective of this study was to assess associations of neighborhood opportunity and mortality risk in children and their caregivers over 11 years.

METHODS
Participants included 1 025 000 children drawn from the Mortality Disparities in American Communities study, a cohort developed by linking the 2008 American Community Survey to the National Death Index and followed for 11 years. Neighborhood opportunity was measured using the Child Opportunity Index, a measure designed to capture compounding inequities in access to opportunities for health.

RESULTS
Using hazard models, we observed inverse associations between Child Opportunity Index quintile and deaths among child and caregivers. Children in very low opportunity neighborhoods at baseline had 1.30 times the risk of dying over follow-up relative to those in very high opportunity neighborhoods (95% confidence interval [CI], 1.15–1.45), and this excess risk attenuated after adjustment for household characteristics (hazard ratio, 1.15; 95% CI, 0.98–1.34). Similarly, children in very low opportunity neighborhoods had 1.57 times the risk of experiencing the death of a caregiver relative to those in very high opportunity neighborhoods (95% CI, 1.50–1.64), which remained after adjustment (hazard ratio, 1.30; 95% CI, 1.23–1.38).

CONCLUSIONS
Our analyses advance understanding of the adverse consequences of inequitable neighborhood contexts for child well-being and underscore the potential importance of place-based policies for reducing disparities in child and caregiver mortality.