bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergence of zoonotic sporotrichosis due to Sporothrix brasiliensis in Minas Gerais, Brazil: A molecular approach to the current animal disease
Authors: Colombo Salene Angelini , Bicalho Gustavo Canesso , de Oliveira Camila Stefanie Fonseca , de Magalhães Soares Danielle Ferreira , Salvato Lauranne Alves , Keller Kelly Moura , Bastos Camila de Valgas e , Morais Maria Helena Franco , Rodrigues Anderson Messias , Cunha João Luis Reis , de Azevedo Maria Isabel 
Published: July 2023

AbstractSporotrichosis is a neglected fungal zoonosis with significant impacts on human and animal health. Accurate diagnosis, treatment, and understanding of the transmission dynamics of Sporothrix species are essential for mitigating the spread of sporotrichosis. This study aimed to identify the Sporothrix species involved in the ongoing outbreaks of animal sporotrichosis in the metropolitan region of Belo Horizonte, Minas Gerais, Brazil, and analyse the phylogenetic relationships between pathogenic species to investigate the outbreak origin. Additionally, to better understand the evolution of the disease, we conducted a retrospective survey of positive feline and canine cases from November 2017 to July 2021 with proven cultures for Sporothrix. A significant increase in animal cases over the last 4 years was observed, with cats being the most affected host. Sporothrix brasiliensis was the predominant agent in 100% of the clinical isolates (n = 180) molecularly identified. Phylogenetic and haplotype analysis points towards the cases isolated from Minas Gerais sharing the haplotype originating from a long‐lasting outbreak of cat‐transmitted sporotrichosis in Rio de Janeiro, however, with a secondary contribution from genotypes circulating in other outbreaks in Brazil. Thus, we present clear evidence of the circulation of different S. brasiliensis genotypes associated with animal sporotrichosis in the metropolitan region of Belo Horizonte. Genetic monitoring can contribute to understanding the causal agent for zoonotic sporotrichosis in epidemiological processes and help to implement disease prevention and control measures.
Complex eco‐evolutionary responses of a foundational coastal marsh plant to global change
Authors: Vahsen Megan L. , Kleiner Helena S. , Kodak Haley , Summers Jennifer L. , Vahsen Wendy L. , Blum Michael J. , Megonigal J. Patrick , McLachlan Jason S. 
Published: July 2023

Summary

Predicting the fate of coastal marshes requires understanding how plants respond to rapid environmental change. Environmental change can elicit shifts in trait variation attributable to phenotypic plasticity and act as selective agents to shift trait means, resulting in rapid evolution. Comparably, less is known about the potential for responses to reflect the evolution of trait plasticity.

Here, we assessed the relative magnitude of eco‐evolutionary responses to interacting global change factors using a multifactorial experiment. We exposed replicates of 32 Schoenoplectus americanus genotypes ‘resurrected’ from century‐long, soil‐stored seed banks to ambient or elevated CO2, varying levels of inundation, and the presence of a competing marsh grass, across two sites with different salinities.

Comparisons of responses to global change factors among age cohorts and across provenances indicated that plasticity has evolved in five of the seven traits measured. Accounting for evolutionary factors (i.e. evolution and sources of heritable variation) in statistical models explained an additional 9–31% of trait variation.

Our findings indicate that evolutionary factors mediate ecological responses to environmental change. The magnitude of evolutionary change in plant traits over the last century suggests that evolution could play a role in pacing future ecosystem response to environmental change.
The impact of childhood psoriasis on the quality of life of parents and caregivers
Authors: Imhof Reese L. , Eton David T. , Tollefson Megha M. 
Published: July 2023

AbstractWe used the Psoriasis Caregiver Impact Scale to explore the quality of life (QoL) of parents/caregivers of children with psoriasis. We found that the QoL of parents of children with psoriasis is negatively affected in numerous domains including family and social life, emotional health, work, activities, and finances.
Clinical periodontal diagnosis
Authors: Salvi Giovanni E. , Roccuzzo Andrea , Imber Jean‐Claude , Stähli Alexandra , Klinge Björn , Lang Niklaus P. 
Published: July 2023

AbstractPeriodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior to periodontal therapy, following active therapy, and during long‐term supportive care. In addition, patient‐reported outcomes such as increased tooth mobility, migration, and tilting should also be considered. More important to the patient, however, is the fact that assessment of signs of periodontal diseases must be followed by an appropriate treatment plan. Furthermore, it should be realized that clinical and radiographic periodontal diagnosis is based on signs which may not reflect the presence of active disease but rather represent the sequelae of a previous bacterial challenge. Hence, the aim of the present review is to provide a summary of clinical and radiographic diagnostic criteria required to classify patients with periodontal health or disease.
Sedimentary evolution and sequence stratigraphy of Ediacaran high‐grade phosphorite–dolomite–shale successions of the Bocaina Formation (Corumbá Group), Central Brazil: Implications for the Neoproterozoic phosphogenic event
Authors: Hippertt João Pedro T. M. , Rudnitzki Isaac D. , Morais Luana , Freitas Bernardo , Romero Guilherme R. , Fernandes Henrique A. , Leite Mariangela G. P. , Leme Juliana M. , Boggiani Paulo , Trindade Ricardo I. F. 
Published: July 2023

AbstractExtensive phosphorite deposition is observed in the Neoproterozoic after a prolonged hiatus during most of the Mesoproterozoic era. This event is thought to represent an important record of major palaeoenvironmental, palaeoceanographic and biotic changes that shaped Neoproterozoic ecosystems, suggesting close relationships between phosphogenesis and the preservation of key Ediacaran biotas. However, high‐grade Ediacaran phosphorite deposits are relatively uncommon, diminishing the opportunity to test current phosphate mineralization–deposition models and their implications for Neoproterozoic research. In this scenario, widespread Ediacaran phosphorite–dolomite–shale successions of the Bocaina Formation (Corumbá Group – Central Brazil) are poorly explored in international literature. Nevertheless, recent advances in phosphate exploration gave access to continuous drill core sections and freshly opened mine pits, revealing an unprecedented record of complex phosphatic successions featuring the occurrence of Ediacaran microfossils assigned to the Doushantuo–Pertatataka assemblages. This work seeks to constrain main lithofacies, sequence stratigraphy and depositional settings from these phosphatic successions in order to analyse the sedimentary evolution of the unit under the current Neoproterozoic phosphorite research framework. These results indicate that the Bocaina Formation records secular sustained phosphate deposition. These deposits are related to unprecedented, microbialite reef rim phosphorites deposited during a lower accretionary rimmed platform stage, followed by the deposition of Doushantuo‐like, whole platform phosphorites associated with a later, drowned platform stage, therefore, reinforcing the evidence for the operation of strong allogeneic controls on phosphate mineralization–concentration. In addition, this study concludes that fossiliferous Ediacaran phosphatic deposits such as the Bocaina Formation are important to understanding Neoproterozoic phosphogenic events, because they may record the transition from a Precambrian to Phanerozoic‐like phosphogenesis associated with the instauration of the Ediacaran–Cambrian phosphatic taphonomic window. This evidence hints that the growing dataset from the Bocaina Formation may bring new, exciting perspectives for Neoproterozoic research as a whole.
Differential associations and concordance across measures of parent emotion socialization: The role of parent and adolescent emotion dysregulation
Authors: McQuade Julia D. , Breaux Rosanna , Cash Annah R. , Horton Nicholas J. , Azu Margaret A. , Delgado Daylin 
Published: July 2023

AbstractAlthough parent ratings, adolescent ratings, and observations are all utilized to measure parent emotion socialization during adolescence, there is a lack of research examining measurement differences and concordance. Thus, the present study compared three measures of parent supportive and nonsupportive emotion socialization and examined whether parent and adolescent emotion dysregulation differentially related to these measures or moderated concordance across measures. Participants were a community sample of 92 adolescent‐parent dyads. Adolescents were 13–17 years‐old (M = 15.5, SD = 1.1), 41 were female and 51 were male; 87% of parents identified as mothers. Observed emotion socialization was coded during a parent‐adolescent conflict discussion task. The adolescent and parent also rated the parent's supportive and nonsupportive reactions to the adolescent's negative emotions; they each also rated their own emotion dysregulation. Due to data collection timing, COVID‐19 family stress was also assessed and explored as a covariate in analyses. Bivariate correlations indicated that there were weak and non‐significant correlations across emotion socialization measures. Multilevel models indicated that measures of parent emotion socialization were differentially associated with adolescent emotion dysregulation, with adolescent emotion dysregulation relating significantly to adolescent ratings, but not observations or parent ratings, of parent emotion socialization. In addition, multiple regressions indicated that there was less concordance across measures when parents were higher in emotion dysregulation. Results suggest that measurement may influence researchers’ conclusions about how youth adjustment relates to parent emotion socialization. Additionally, there may be even lower agreement across measures of parent emotion socialization when parents have emotional challenges.
Effect of weather conditions on efficacy of different herbicides used in Bromus sterilis control
Authors: Jursík Miroslav , Kolářová Michaela , Kučera Josef 
Published: July 2023

AbstractEfficacy of herbicides is strongly affected by weather conditions shortly before and after application. Small‐plot field trials were carried out in winter wheat in north‐west Bohemia, Czech Republic, Central Europe from 2011 to 2018. The relationship between meteorological characteristics and efficacy of acetolactate synthase inhibiting herbicides (mesosulfuron + iodosulfuron, propoxycarbazone and pyroxsulam) on Bromus sterilis was studied. The effects of precipitation before and after herbicide application, mean temperature and sunshine hours after the application were found to be statistically significant. The total precipitation 30 days before herbicide application had the greatest effect on herbicide efficacy. Mean efficacy significantly increased with increasing precipitation, when mean temperatures 5 days after treatment were above 9°C. The herbicide mesosulfuron + iodosulfuron was most affected by amount of precipitation while efficacy of pyroxsulam was minimally affected. When total rainfall amounted to 30 mm in the 20–40 days after herbicide application, there was no significant effect of total rainfall before herbicide application. In order to prepare the best weed control strategy against B. sterilis, weather conditions before and after the application term should be considered so that the growers can adjust for proper application timing and be prepared for a second application with a suitable herbicide.
On simply normal numbers with digit dependencies
Authors: Becher Verónica , Marchionna Agustín , Tenenbaum Gérald 
Published: July 2023

AbstractGiven an integer and a set of prime numbers, the set of Toeplitz numbers comprises all elements of [0, b[ whose digits in the base‐b expansion satisfy for all and . Using a completely additive arithmetical function, we construct a number in that is simply Borel normal if, and only if, . We then provide an effective bound for the discrepancy.
Thermal stability of stealth and de Sitter spacetimes in scalar-tensor gravity
Authors: Giardino Serena , Giusti Andrea , Faraoni Valerio 
Published: July 2023

AbstractStealth solutions of scalar-tensor gravity and less-known de Sitter spaces that generalize them are analyzed regarding their possible role as thermal equilibria at non-zero temperature in the new first-order thermodynamics of scalar-tensor gravity. No stable equilibria are found, further validating the special role of general relativity as an equilibrium state in the landscape of gravity theories, seen through the lens of first-order thermodynamics.
Analysis of black hole solutions in parabolic class using neural networks
Authors: Hatefi Ehsan , Hatefi Armin , López-Sastre Roberto J. 
Published: July 2023

AbstractIn this paper, we introduce a numerical method based on Artificial Neural Networks (ANNs) for the analysis of black hole solutions to the Einstein-axion-dilaton system in a high dimensional parabolic class. Leveraging a profile root-finding technique based on General Relativity we describe an ANN solver to directly tackle the system of ordinary differential equations. Through our extensive numerical analysis, we demonstrate, for the first time, that there is no self-similar critical solution for the parabolic class in the high dimensions of space-time. Specifically, we develop 95% ANN-based confidence intervals for all the solutions in their domains. At the 95% confidence level, our ANN estimators confirm that there is no black hole solution in higher dimensions, hence the gravitational collapse does not occur. Results provide some doubts about the universality of the Choptuik phenomena. Therefore, we conclude that the fastest-growing mode of the perturbations that determine the critical exponent does not exist for the parabolic class in the high dimensions.
Shadow and stability of quantum-corrected black holes
Authors: Yang Jinsong , Zhang Cong , Ma Yongge 
Published: July 2023

AbstractRecently the quantum Oppenheimer–Snyder gravitational collapse model has been proposed in loop quantum gravity, providing quantum-corrected Schwarzschild spacetimes as the exterior of the collapsing dust ball. In this paper, the quantum gravity effects on the black hole shadows in this model are studied, and the stability of the quantum-corrected black holes is also analyzed by calculating the quasinormal modes. It turns out that the quantum correction always shrinks the radius of shadows, and the quantum-corrected black holes are stable against the scalar and vector perturbations.
Probing regular MOG static spherically symmetric spacetime using greybody factors and quasinormal modes
Authors: Al-Badawi Ahmad 
Published: July 2023

AbstractWe investigate the behavior of the regular modified gravity (MOG) static spherically symmetric black hole (BH) under massless scalar perturbation, gravitational perturbation, and massless Dirac perturbation. The dimensionless parameter $$\left( \alpha \right) $$

α

distinguishes this BH from a Schwarzschild BH. We derive the effective potential equations for three perturbations in the regular MOG BH. Using the derived potentials, we calculate the bounds of greybody factors (GFs). Next, we investigate the quasinormal mode (QNM) of the MOG BH by implementing the WKB method of sixth order. By analyzing the influence of the MOG parameter $$\alpha $$
α
for the BH we study on GF and QNM, we found that as $$\alpha $$
α
increases, the GFs increase proportionally. However, both gravitational wave oscillation frequency and damping decrease as $$\alpha $$
α
increases. Moreover, we examine the behavior of QNMs by considering how their frequency changes with the shape of potentials. As a result, we found that the frequency behavior is like the quantum mechanical one. The faster the wave decays, the larger the potential.
Parton labeling without matching: unveiling emergent labelling capabilities in regression models
Authors: Qiu Shikai , Han Shuo , Ju Xiangyang , Nachman Benjamin , Wang Haichen 
Published: July 2023

AbstractParton labeling methods are widely used when reconstructing collider events with top quarks or other massive particles. State-of-the-art techniques are based on machine learning and require training data with events that have been matched using simulations with truth information. In nature, there is no unique matching between partons and final state objects due to the properties of the strong force and due to acceptance effects. We propose a new approach to parton labeling that circumvents these challenges by recycling regression models. The final state objects that are most relevant for a regression model to predict the properties of a particular top quark are assigned to said parent particle without having any parton-matched training data. This approach is demonstrated using simulated events with top quarks and outperforms the widely-used $$\chi ^2$$

χ
2

method.
Viscoelastic response of confined powder under large strain oscillations, characterized by its noise temperature
Authors: Handa Rishab , Wagner Christian , Fiscina Jorge Eduardo 
Published: July 2023

Abstract
We report a study on granular matter with and without small additions of silicon oil, under low-frequency and large amplitude oscillatory shear strain under constant normal pressure, by running experiments with a rotational rheometer with a cup-and-plate geometry. We analysed the expansion with the Chebyshev polynomials of the orthogonal decomposition of stress–strain Lissajous–Bowditch loops. We found the onset of the strain amplitude for the yielding regime indicated a regime change from filament-like structures of grains to grain rearrangements for the dry granulate and from oscillations to the breaking and regeneration of liquid bridges for wet granulates. We have shown that this viscoelastic dynamics can be characterized by a noise temperature following Sollich et al. (Phys Rev Lett https://doi.org/10.1103/PhysRevLett.78.2020, 1997). The analysis of the first harmonics of the Chebyshev expansion showed that the state of disorder of dry and wet granular matter in pre-yielding and yielding regimes involved ensembles of different inherent states; thus, each of them was governed by a different noise temperature. The higher-order harmonics of the Chebyshev expansion revealed a proportionality between the viscous nonlinearity and the variation in the elastic nonlinearity induced by the deformation, which shows the coupling between the elastic deformation and the viscous flow of mesoscopic-scale structures.

Graphic abstract
Comparing Heuristic Rules and Masked Language Models for Entity Alignment in the Literature Domain
Authors: Piché Dominique , Font Ludovic , Zouaq Amal , Gagnon Michel 
Published: July 2023

The cultural world offers a staggering amount of rich and varied metadata on cultural heritage, accumulated by governmental, academic, and commercial players. However, the variety of involved institutions means that the data are stored in as many complex and often incompatible models and standards, which limits its availability and explorability by the greater public.
The adoption of Linked Open Data technologies allows a strong interlinking of these various databases as well as external connections with existing knowledge bases. However, as they often contain references to the same entities, the delicate issue of entity alignment becomes the central challenge, especially in the absence or scarcity of unique global identifiers.
To tackle this issue, we explored two approaches, one based on a set of heuristic rules and one based on masked language models, or masked language models (MLMs). We compare these two approaches, as well as different variations of MLMs, including some models trained on a different language, and various levels of data cleaning and labeling. Our results show that heuristics are a solid approach but also that MLM-based entity alignment obtains better performance coupled with the fact that it is robust to the data format and does not require any form of data preprocessing, which was not the case of the heuristic approach in our experiments.
Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins
Authors: Aasted Mikkel K.M. , Groen Aaron C. , Keane John T. , Dabelsteen Sally , Tan Edwin , Schnabel Julia , Liu Fang , Lewis Hyeon-Gyu S. , Theodoropulos Constantine , Posey Avery D. , Wandall Hans H. 
Published: July 2023

Abstract
The lack of antibodies with sufficient cancer selectivity is currently limiting the treatment of solid tumors by immunotherapies. Most current immunotherapeutic targets are tumor-associated antigens that are also found in healthy tissues and often do not display sufficient cancer selectivity to be used as targets for potent antibody-based immunotherapeutic treatments, such as chimeric antigen receptor (CAR) T cells. Many solid tumors, however, display aberrant glycosylation that results in expression of tumor-associated carbohydrate antigens that are distinct from healthy tissues. Targeting aberrantly glycosylated glycopeptide epitopes within existing or novel glycoprotein targets may provide the cancer selectivity needed for immunotherapy of solid tumors. However, to date only a few such glycopeptide epitopes have been targeted. Here, we used O-glycoproteomics data from multiple cell lines to identify a glycopeptide epitope in CD44v6, a cancer-associated CD44 isoform, and developed a cancer-specific mAb, 4C8, through a glycopeptide immunization strategy. 4C8 selectively binds to Tn-glycosylated CD44v6 in a site-specific manner with low nanomolar affinity. 4C8 was shown to be highly cancer specific by IHC of sections from multiple healthy and cancerous tissues. 4C8 CAR T cells demonstrated target-specific cytotoxicity in vitro and significant tumor regression and increased survival in vivo. Importantly, 4C8 CAR T cells were able to selectively kill target cells in a mixed organotypic skin cancer model having abundant CD44v6 expression without affecting healthy keratinocytes, indicating tolerability and safety.