bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of stress wave propagation across a non-persistent joint based on a boundary integral equation method
Authors: Li Jianchun , Nie Mengmeng , Li Xing 
Published: May 2023

AbstractStudies on stress wave propagation across persistent joints have been conducted extensively. Nevertheless, there exists a consensus that non-persistent joints are widely and densely distributed, which have a profound impact on wave propagation in jointed rock masses. A boundary integral equation method is suggested in this paper to investigate the characteristics of transmitted wave field for the case of stress wave propagation across a single non-persistent joint. The displacement continuity and discontinuity boundaries are combined in the method. The method presented in the current study is applicable to the analysis of wave propagation across non-persistent joints with arbitrary incident angles. Then, taking a single non-persistent joint arranged with only one joint segment as an example, the applicability of the method in dealing with the problems of wave propagation is verified by comparing the results with those from the discrete element method and analytical methods. Subsequently, parametric studies are carried out, including the effects of joint-segment length, rock-bridge length, wave frequency and incident angle on the transmitted wave. The result indicates that the existence of non-persistent joint makes the transmitted displacement field different from that of persistent joint, because the scattered wave is produced during the process of wave propagation. The displacement amplitude may be amplified evidently in some regions and the spatial distribution pattern of the transmission coefficient is closely related to the joint-segment length, rock-bridge length and incident wavelength.
Using Immersive Virtual Reality in an Online Biology Course
Authors: Majewska Ania A. , Vereen Ethell 
Published: May 2023

AbstractInterest in virtual reality (VR) for teaching and learning in higher education is growing, given its many potential applications. VR offers a socially interactive environment with novel ways to engage students with materials, objects, and activities and provide students with experiences such as “field trips” that would be otherwise very difficult. Preliminary work indicates overall positive gains in student learning across disciplines compared to other technology and traditional techniques, although more studies are needed to better our understanding of this tool. We employed an “immersive” VR (with a head-mounted display) in an online course which provided students with the opportunity to interact with peers and engage in activities. We asked about perceptions of the learning experience with the technology and how using VR impacts students’ performance. We also noted the benefits and challenges of VR in an online course. Students perceived VR as a helpful component of the course, although performance on the cardiovascular unit assessment did not differ compared to the previous semester without VR.
Linguistic Analysis of Generic-Generic Drug Name Pairs Prone to Wrong-Drug Errors for which Tall-Man Lettering is Recommended
Authors: Karet Gail B. 
Published: May 2023

Abstract
Objective
The Institute for Safe Medication Practices (ISMP) and the United States Food and Drug Administration (FDA) disseminated widely used lists of drug name pairs involved in wrong-drug errors, for which they recommended tall-man lettering (TML). Linguistic similarity is believed responsible for confusion of these drugs. This study aims to quantify linguistic similarity and other linguistic properties of these generic-generic name pairs.

Methods
The FDA’s Phonetic and Orthographic Computer Analysis (POCA) software was used to generate numerical similarity scores for the generic-generic name pairs on these lists and to identify conflicts between these names and the names of other marketed products. Within each pair, differences in name length and the number of identical prefix (initial) letters and suffix (final) letters were determined.

Results
The selected pairs shared a mean of 2.5 (± 1.8) identical prefix letters and 3.2 (± 2.9) identical suffix letters. The mean POCA score 69.5 (± 9.7), indicated moderate-to-high similarity. POCA scores for individual pairs ranged from 90 (most similar) to 46 (least similar). Individual names averaged 11.2 (± 9.1) high-similarity conflicts with names of other marketed drugs.

Conclusions
POCA analysis could be a valuable tool in determining whether linguistic similarity contributes to specific wrong-drug errors. The finding of 11.2 (± 9.1) high-similarity conflicts with names of other marketed drugs is more than for candidate names USAN accepts and suggests the names on the FDA and ISMP lists are linguistically problematic.
Development of an Implementation Blueprint to Scale-Up Contraception Care for Adolescents with Psychiatric Conditions in a Pediatric Hospital
Authors: Hyzak Kathryn A. , Bunger Alicia C. , Herrmann Samantha A. , Kerlek Anna , Lauden Stephanie , Dudley Sam , Underwood Abigail , Berlan Elise D. 
Published: May 2023

AbstractImplementation blueprints are comprehensive plans that describe implementation strategies, goals, timelines, and key personnel necessary for launching new interventions. Although blueprints are a foundational step in driving intervention rollout, little is known about how blueprints are developed, refined, and used in practice. The objective of this study was to describe a systematic, collaborative approach to developing, refining, and utilizing a formal implementation blueprint for scaling up the Contraception Care at Behavioral Health Pavilion (CC@BHP) intervention for adolescents hospitalized in psychiatric units within a pediatric hospital in the United States. In Stage 1 (Planning/Preparation), we assembled a Research Advisory Board (RAB) of 41 multidisciplinary members and conducted a formative evaluation to identify potential barriers to CC@BHP implementation. Barriers were mapped to implementation strategies using the Consolidated Framework for Implementation Research (CFIR) and Expert Recommendations for Implementing Change (ERIC) tool and used to create an initial blueprint. In Stage 2 (Development/Implementation), RAB members used activity logs to track implementation activities over the 18-month study period, which were then mapped to formal implementation strategies used to further develop the blueprint. About 30% of strategies were situated in the ‘Train and Educate Stakeholders’ ERIC category, 20% in ‘Use Evaluative and Iterative Strategies,’ and 16% in ‘Develop Stakeholder Interrelationships’ category. In Stage 3 (Synthesis/Refinement), the final blueprint was refined, consisting of 16 goals linked to 10 strategies for pre-implementation and 6 strategies for implementation. Feedback on the blueprint emphasized the role of the project champion in translating the blueprint into smaller, actionable steps for implementers.
SiNx Coating Deposition on CoCr by Plasma-Enhanced Chemical Vapor Deposition
Authors: Zhou Huasi , Persson Cecilia , Xia Wei , Engqvist Håkan 
Published: May 2023

AbstractCobalt chromium alloys (CoCr) are commonly used as total disc replacement components. However, there are concerns about its long-term biological effects. Coating the CoCr with a ceramic could improve the implant’s biocompatibility and wear resistance. Silicon nitride (SiNx) coatings have emerged as a recent alternative to this end. While many have evaluated physical vapour deposition (PVD) techniques to deposit these coatings, plasma-enhanced chemical vapour deposition (PECVD) may provide certain advantages. For example, it may allow for low-temperature depositions as well as more uniform coatings of complex structures. In this study, silicon nitride (SiNx) coatings with different nitrogen-to-silicon (N/Si ratio) compositions (0.65, 1.16 and 1.42) were deposited onto CoCr substrates by PECVD. It was found that the SiNx coating deposited at an NH3 flow rate of 30 sccm (i.e., N/Si ratio of 1.42), had the highest hardness and elastic modulus, 13.19 ± 1.29 GPa and 132.76 ± 9.32 GPa, respectively. While a coating roughness adequate for the application could be measured, further optimization of the coating adhesion is needed to adequately evaluate its wear properties. It was concluded that the PECVD SiNx coating deposited at an NH3 flow rate of 30 sccm showed the highest potential for the intended application.
Exploring 3D spatial morphology using multilayered space syntax, network science and wi-fi log data
Authors: Zhang Junwei , Senousi Ahmad M. , Zhao Pengxiang , Law Stephen , Liu Xintao 
Published: May 2023

AbstractSpatial morphology of 2D space has been well studied at the scales of building, community, and city in space syntax literature. Space syntax decomposes continuous geographic space into a set of unique axial lines and represents them as a spatial network to analyze spatial morphology. However, 3D spatial morphology remains largely unexplored, partially due to limited data access and methodological constraints. Motivated by the multilayered network literature in network science, this work extends the conventional 2D space syntax axial network into a multilayered axial network to explore the spatial morphology of a university campus. Scaling properties are discovered from several aspects of the constructed spatial network (e.g., degree, local integration). The relationship between spatial morphology and route-based pedestrian flow is evaluated using a large Wi-Fi log dataset and multiple regression analysis. We found a significant correlation between the two, with a correlation coefficient of 0.756 and r2 of 0.571. Four network features (i.e., local depth, geometric length, eigenvector, and betweenness), are found to significantly shape the pedestrian flow. The results of community detection show the effectiveness of multilayered space syntax analysis in depicting functional areas of campus, despite the complex nature of 3D space. Whilst a limitation of this research is the need to account for the 3D angular route preferences when characterizing the morphology of campus and the flow estimated based on the shortest routes using the Dijkstra algorithm.
The Welfare Cost of Beijing’s Lottery Policy: Evidence from a Contingent Valuation Survey
Authors: Qin Ping , Quan Yifei , Liu Antung A. , Linn Joshua , Yang Jun 
Published: May 2023

AbstractMotivated by traffic congestion and air pollution, Beijing is one of several major cities to restrict vehicle ownership by requiring residents to win a lottery for the right to obtain an additional car. We examine the welfare cost of preventing people from owning cars because of misallocation: under a lottery, some individuals with low willingness to pay (WTP) for cars can obtain cars, while other individuals with high WTP cannot. We estimate welfare costs using a new contingent valuation method survey of Beijing lottery participants which we designed and conducted explicitly for this purpose. We find that restricting vehicle ownership reduced private welfare by 26 billion yuan. Back-of-the-envelope calculations suggest that the benefits of lower congestion and pollution roughly equal the costs. Our WTP estimates indicate a net welfare gain of approximately 32 billion yuan if Beijing’s lottery were replaced with an auction, which is similar to previous estimates.
Hard Law and Soft Law Regulations of Artificial Intelligence in Investment Management
Authors: BUCZYNSKI Wojtek , STEFFEK Felix , CUZZOLIN Fabio , JAMNIK Mateja , SAHAKIAN Barbara 
Published: May 2023

AbstractArtificial Intelligence (‘AI’) technologies present great opportunities for the investment management industry (as well as broader financial services). However, there are presently no regulations specifically aiming at AI in investment management. Does this mean that AI is currently unregulated? If not, which hard and soft law rules apply?Investments are a heavily regulated industry (MIFID II, UCITS IV and V, SM&CR, GDPR etc). Most regulations are intentionally technology-neutral. These regulations are legally binding (hard law). Recent years saw the emergence of regulatory and industry publications (soft laws) focusing specifically on AI. In this Article we analyse both hard law and soft law instruments.The contributions of this work are: first, a review of key regulations applicable to AI in investment management (and oftentimes by extension to banking as well) from multiple jurisdictions; second, a framework and an analysis of key regulatory themes for AI.
The evolution of life cycle assessment in the food and beverage industry: A review
Authors: Chitaka Takunda Y. , Goga Taahira 
Published: May 2023

Abstract
Life cycle assessment (LCA) has been progressively used as an tool to quantify and compare environmental impacts in the food and beverage industry. This paper reviews LCAs on single-use food and beverage plastic products from January 2000 to June 2022. Studies are also analysed in the context of marine plastic pollution which is a global concern. A total of 91 studies were reviewed with 44% conducted for the European region. Findings suggest that most studies follow the traditional approach and structure of LCA with some studies focusing on global warming potential and others incorporating aspects such as life cycle costs and mass-based indicators. A total of 62% of reviewed studies had a cradle-to-grave scope. LCA studies can be influenced by public discourse, for example, the rising concern surrounding plastic marine pollution. From 2019, additional environmental indicators have been included in LCAs wherein the product is a major contributor to pollution. To date, six studies have proposed marine litter indicators. In future years, we can expect further development of life cycle impact assessment methods to reflect concerns in the public discourse. This includes methodologies for assessing circularity or plastic pollution. Furthermore, product foci will continue to follow popular trends.
AROMA: Anionic ring-opening monomer addition of allyl glycidyl ether to methoxy poly(ethylene glycol) for the synthesis of sequence-controlled polymers
Authors: Schneider Sven , Schwalm Benedikt L. , Theato Patrick 
Published: May 2023

Abstract
Herein, a new method to synthesise epoxide-based sequence-controlled polymers via anionic ring-opening monomer addition, a form of anionic ring-opening polymerisation, is presented. This technique allows in combination with post-polymerisation modification (PPM) reactions for the successful preparation of modified mPEG-b-oligo(allyl glycidyl ether) featuring the incorporation of one repeating unit on average at a time. Due to the possible introduction of a vast variety of molecules to the polymeric system via PPM reactions, a multitude of advanced functional polymeric materials can be generated. This, in combination with the chain extension reactions, allows for the synthesis of well-controlled and programmable architectures with particular properties. The structure of the sequence-controlled polymer was confirmed via 1H NMR spectroscopy, size exclusion chromatography, attenuated total reflection Fourier-transform infrared spectroscopy, and differential scanning calorimetry.
The Arabesque of Script and Metaphor in Islamic Art
Authors: Risser Rita Elizabeth 
Published: May 2023

AbstractThe use of script as an aesthetic device is longstanding in Islamic art. Indeed, one of the earliest forms of Islamic art are terracotta oil lamps with text inscribed on their surface.2 These inscriptions are not merely decorative but also reference the light emitted from the lamps as a metaphor for revelation. As I will show, the use of script in Islamic art is not only meant to delight the eye; it is, moreover, a cognitively faceted aesthetic device. Following an overview of script as an aesthetic device in Islamic art, I survey its legacy in the contemporary art world of the Middle East.
The evolution of motivational interviewing
Authors: Miller William R. 
Published: May 2023

AbstractThis review traces the development of motivational interviewing (MI) from its happenstance beginnings and the first description published in this journal in 1983, to its continuing evolution as a method that is now in widespread practice in many professions, nations and languages. The efficacy of MI has been documented in hundreds of controlled clinical trials, and extensive process research sheds light on why and how it works. Developing proficiency in MI is facilitated by feedback and coaching based on observed practice after initial training. The author reflects on parallels between MI core processes and the characteristics found in 70 years of psychotherapy research to distinguish more effective therapists. This suggests that MI offers an evidence-based therapeutic style for delivering other treatments more effectively. The most common use of MI now is indeed in combination with other treatment methods such as cognitive behaviour therapies.
Stepping Into an Equatorial Plasma Bubble With a Swarm Overfly
Authors: Spogli L. , Alfonsi L. , Cesaroni C. 
Published: May 2023

AbstractESA's Swarm constellation entered in a “overfly” configuration in the period between September and October 2021, when the longitudinal distance between the lower pair and the upper satellite was at its minimum since the launch of the spacecrafts. In addition, the local time of the nighttime tracks was favorable to detect and study the morphology of post‐sunset equatorial plasma bubbles (EPBs). In this study, we focus on the Swarm overfly occurring between 00:41 UT and 00:59 UT on 30 September 2021, which covered one of the most densely instrumented regions for the study of the ionospheric irregularities embedded in the EPBs: the South American sector. By exploiting the use of ground‐based receivers of Global Navigation Satellite System (GNSS) signals in combination with the Swarm plasma density measurements, we study the irregularities in the EPB formed at ∼60°W and investigate the different scales of the irregularities and the cascading processes along the magnetic flux tubes. We also highlight how diffusion along the magnetic field lines occurs simultaneously with the plasma uplift, contributing then to the correct interpretation of the EPB evolution and decay process. The precious overfly conditions also allow the introduction of ionosphere‐related quantities, evaluated across the tracks at satellite altitudes enlarging the possibilities given by the same quantities already available along the tracks. Such opportunity envisages the possibility to proxy the impact of EPBs on GNSS signals with Low‐Earth Orbit satellite data provided by future missions specifically dedicated to the characterization of the near‐Earth environment and ionospheric studies.
Long-term safety and maintenance of response with esketamine nasal spray in participants with treatment-resistant depression: interim results of the SUSTAIN-3 study
Authors: Zaki Naim , Chen Li , Lane Rosanne , Doherty Teodora , Drevets Wayne C. , Morrison Randall L. , Sanacora Gerard , Wilkinson Samuel T. , Popova Vanina , Fu Dong-Jing 
Published: May 2023

AbstractPatients with treatment-resistant depression (TRD) have higher rates of relapse and pronounced decreases in daily functioning and health-related quality of life compared to patients with major depressive disorder who are not treatment-resistant, underscoring the need for treatment choices with sustained efficacy and long-term tolerability. Adults with TRD who participated in ≥1 of 6 phase 3 “parent” studies could continue esketamine treatment, combined with an oral antidepressant, by enrolling in phase 3, open-label, long-term extension study, SUSTAIN-3. Based on their status at parent-study end, eligible participants entered a 4-week induction phase followed by an optimization/maintenance phase, or directly entered the optimization/maintenance phase of SUSTAIN-3. Intranasal esketamine dosing was flexible, twice-weekly during induction and individualized to depression severity during optimization/maintenance. At the interim data cutoff (01 December 2020), 1148 participants were enrolled, 458 at induction and 690 at optimization/maintenance. Mean (median) cumulative duration of maintenance esketamine treatment was 31.5 (37.7) months (totaling 2769 cumulative patient-years). Common treatment-emergent adverse events (≥20%) were headache, dizziness, nausea, dissociation, somnolence, and nasopharyngitis. Mean Montgomery–Åsberg Depression Rating Scale (MADRS) total score decreased during induction, and this reduction persisted during optimization/maintenance (mean [SD] change from the baseline to the endpoint of each phase: induction −12.8 [9.73]; optimization/maintenance +1.1 [9.93]), with 35.6% and 46.1% of participants in remission (MADRS total score ≤12) at induction and optimization/maintenance endpoints, respectively. Improvement in depression ratings generally persisted among participants who remained in maintenance treatment, and no new safety signal was identified during long-term treatment (up to 4.5 years) using intermittent-dosed esketamine in conjunction with daily antidepressant.
Nitroglycerin: a comprehensive review in cancer therapy
Authors: Meunier Mélina , Yammine Aline , Bettaieb Ali , Plenchette Stéphanie 
Published: May 2023

AbstractNitroglycerin (NTG) is a prodrug that has long been used in clinical practice for the treatment of angina pectoris. The biotransformation of NTG and subsequent release of nitric oxide (NO) is responsible for its vasodilatating property. Because of the remarkable ambivalence of NO in cancer disease, either protumorigenic or antitumorigenic (partly dependent on low or high concentrations), harnessing the therapeutic potential of NTG has gain interest to improve standard therapies in oncology. Cancer therapeutic resistance remains the greatest challenge to overcome in order to improve the management of cancer patients. As a NO releasing agent, NTG has been the subject of several preclinical and clinical studies used in combinatorial anticancer therapy. Here, we provide an overview of the use of NTG in cancer therapy in order to foresee new potential therapeutic avenues.