bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Research of Non-destructive Detection Drive Device for Precision Type Cylindrical Roller Dynamic Unbalance
Authors: Liang Shijie , Duan Mingde , Zhang Zhuangya , Chen Yang , Deng Sier 
Published: March 2023

Abstract
In order to solve the problem of small high-speed precision cylindrical roller, which is difficult to drive and the surface is easily damaged when doing dynamic unbalance detection due to the small size and light mass of the roller, this paper proposes a new drive method, using air flotation non-destructive support instead of V-block or cylindrical surface of the roller and other lossy contact support and air flotation electric spindle combined with vacuum suction cup instead of belt friction drive; establish a mathematical model of cylindrical roller force to study the force of cylindrical roller in the air flotation sleeve during the drive, and through the force analysis, it is shown that under the condition that the structural parameters and material parameters of the drive remain unchanged, the start-up speed of the drive depends on the load-bearing capacity of the air film on the cylindrical roller; the mathematical model of the air film load-bearing capacity and the thickness of the air film is established to study the changing characteristics of the air film load-bearing capacity in the air flotation sleeve, and the correctness of the mathematical model is verified through numerical calculation combined with simulation analysis; the test platform of the drive device based on the non destructive detection of cylindrical roller dynamic unbalance is built to further verify the feasibility of high-speed non-destructive drive of cylindrical rollers and to create favorable conditions for the development of the non-destructive detection instrument for small mass cylindrical rollers dynamic unbalance.
Comparison between outcomes of Marsupialization and Lay Open Techniques in the Management of Pilonidal Sinus
Authors: Ghalib Hawar Ali , Ameen Shorsh Hama Hussein , Hussein Hussein Ali 
Published: March 2023

Abstract
Background

Different surgical strategies emerged as a pilonidal disease (PNS) became more prevalent. There is considerable debate over the best surgical management.

Objective

This study aimed to compare the outcomes of marsupialization (MP) vs laying open (LO) techniques in studied patients. Patients and Methods
This study was conducted on 200 consecutive patients with chronic PNS who operated either the excision and MP technique (Group 1, no.=100) or excision and LO technique (Group 2, no.=100) in Hospital, Sulaimaniyah, Iraq, from January 2012 to January 2022. The patients' socio-demographics, perioperative data, complications and recurrences were collected using a well-designed, self-prepared questionnaire. Also, the patient’s data was evaluated after surgery regarding postoperative pain, satisfaction, healing and dressing time, incapacity to work and overall postoperative complications.

Results

Most patients were aged 20–29 years (40.5%), males (71.5%), had working hours for > 6 hours (57%), had no family history of PNS (86.0%), presented with pain (44.83%), and with hirsutism (41.5%). For postoperative pain, 39.5% of the patients had severe pain, 38% had moderate, and 22.5% had mild, with highly significant differences (p = 0.000) between both studied groups. Concerning patient postoperative satisfaction, most patients (32.5%) had good and least had excellent (6.0%) satisfaction, with highly significant differences (p = 0.000) between both studied groups. Moreover, for the association between the outcomes of both used techniques, a substantial correlation between both groups was found for incapacity for regular daily activity (p = 0.046), healing time (p = 0.000), dressing time (p = 0.000), infection, dehiscence, bleeding and recurrence (p = 0.045).

Conclusion

MP was the preferred technique over LO in managing postoperative patient satisfaction, pain severity, duration of healing, and dressing time, as it had fewer complications with less recurrence rate.
Application of Data Mining in Enterprise Financial Risk Prediction Based on Genetic Algorithm and Linear adaptive optimization
Authors: Yi Xu 
Published: March 2023

Abstract
In the construction of enterprise financial risk prediction model, the obtaining of the optimal solution has a key impact on the prediction effect of the prediction model. Exploring the optimization and improvement of the prediction model to obtain the optimal solution is an urgent problem. In this paper, based on genetic algorithm and data mining technology, a genetic algorithm model based on adaptive improvement is proposed. Through linear adaptive optimization, the optimal solution of complex problems is obtained. When estimating parameters, EM algorithm is used to estimate, so that the final effect of model fusion can reach the expectation. At the same time, it integrates data mining technology, Borderline STATE EasyEnsemble sampling method and SVM intelligent technology to build an optimized comprehensive risk early warning model, which realizes the automatic integration and prediction of financial risks. The adjusted mathematical model is better than the single technical model. This study verified that the prediction ability of the improved model for minority samples has been greatly improved. Under the new method, F1 + F2 + F3 has increased by 14.83% compared with the single F1 feature, and the prediction accuracy of most types of samples has not been reduced. The prediction effect has generally improved. Finally, according to the current situation of enterprise finance, this paper puts forward effective measures to prevent enterprise financial risks.
Clinical analysis of pregnancy outcome of different fertility-sparing surgery for borderline ovarian tumors
Authors: Wang Mingdan , Liu Kui-Ran 
Published: March 2023

Abstract
Background
To retrospectively analyze the different fertility-sparing surgery for patients with borderline ovarian tumors, and study their effects on pregnancy outcome and prognosis, to provide guidance and help clinical workers to choose treatment plans.
Methods
The clinical data of 325 patients with borderline ovarian tumors who underwent fertility-sparing surgery at Shengjing Hospital of China Medical University from 2015 to 2021 were collected. To understand the pregnancy intention and pregnancy outcome of patients through follow-up. The deadline for follow-up was July 2022. After checking and sorting out the data, SPSS25.0 software was used for statistical analysis.
Results
Among 325 borderline ovarian tumor patients undergoing fertility-sparing surgery, 118 patients had fertility desire. The postoperative pregnancy rate was 57.63% (68/118), and the natural pregnancy rate was 83.82% (57/68). Univariate analysis showed that the selection of surgical methods and routes and CA125 had significant effects on pregnancy outcomes (P < 0.05). The pregnancy rate after cystectomy was 69.57% (32/46), unilateral salpingo-oophorectomy was 70.83% (17/24), unilateral salpingo-oophorectomy + contralateral oophorectomy/cystectomy was 44.00% (11/25), and stage surgery with fertility preservation was 34.78% (8/23). There was a statistical difference between cystectomy and stage operation with fertility preservation (P < 0.0083). The variables P < 0.10 in univariate analysis were included in the logistic regression analysis. The results showed that the surgical method affected the pregnancy outcome, and the difference was statistically significant (P < 0.05).
Conclusion
Univariate analysis showed that different surgical methods, surgical approaches, and whether CA125 was positive or not affected the postoperative pregnancy rate of borderline ovarian tumors. Multivariate analysis showed that there was a correlation between the operation mode and the pregnancy outcome after the operation. The pregnancy rate after ovarian cystectomy was better than that of stage operation with fertility preservation. The pregnancy rate after laparoscopy was better than that after laparotomy.
Birth and Regulation of head Extension to Guide Manual perineal Assistance (BREGMA) study (a prospective cohort study)
Authors: Abouelhassan Abdelrahman , Kalis Vladimir , Schüssler Marc , Awwad Hassan , Hassan Rania , Ismail Khaled M. 
Published: March 2023

Abstract
Background: The exact positioning of the dominant hand at the time of manual perineal protection (MPP) is not clearly specified. The main aim of this work was to identify the place on the perineum where pressure needs to be applied to achieve optimal forward fetal head displacement away from the anal sphincters using the bregma to posterior fourchette distance (BFD) and the perineal body length (PBL).
Methods: This was a two-center study. Term cephalic singleton nulliparous women having spontaneous vaginal delivery were considered eligible for recruitment into the study. Once crowning was diagnosed and just prior the initiation of manual perineal protection (MPP) or cutting an episiotomy, the BFD and PBL were measured using a standardized measurement protocol.
Results: A total of 100 women (50 women in each center) were recruited into the study. The overall mean BFD was 2.8 ± 0.5 cm. The overall mean PBL was 4.4 ± 0.8 cm. There were no statistically significant differences between the measurements taken in both units regarding BFD or PBL (p = 0.81 and 0.10 respectively). There was a weak correlation between both measurements.
Conclusion: Based on our measured parameters, it seems that the most effective point to apply perineal pressure to displace the head away from the anus is approximately 1 – 1.5 cm anterior to the anal margin. This information will form the bases of future biomechanical studies to confirm their validity.
Treprostinil in the treatment of pediatric patients with severe Idiopathic and Heritable Pulmonary Arterial Hypertension
Authors: He Yuan , Li Qiangqiang , Zhang Chen , Keller Bradley , Gu Hong 
Published: March 2023

Abstract
Introduction: Data have been accumulating that parental treprostinil is safe and effective in pediatric PAH patients. This study was designed to evaluate the efficacy of treprostinil in severe pediatric patients with IPAH and HPAH (IPAH/HPAH). Methods: Children diagnosed with IPAH/HPAH between August 2018 to April 2022 treated with treprostinil at a single center were included in this study. Clinical data including World Health Organization Functional Class (WHO-FC), echocardiography, BNP level and invasive hemodynamics were collected at baseline, short-term follow-up, and at the last available follow-up. Results: Thirty-four children (mean age 9.55 ± 4.90 years, female 65%) were included in this study. Twenty-eight patients (82% of the cohort) carried PAH-related genes mutations with a dominance of BMPR2 mutations. Thirty patients were in WHO-FC III/IV at baseline and most had severely depressed right ventricle systolic function. At short-term follow-up (3.89 months IQR 3.01, 6.39), all patients were alive with significant improvements in clinical symptoms, echocardiographic parameters, and hemodynamics. Eighteen patients who reached WHO-FC I/II discontinued treprostinil during follow-up. One-year and two-year survival rates of the cohort were 90.6% and 68.2%, respectively. Cox regression analysis identified BNP at short-term follow-up and change of peak tricuspid valve regurgitant velocity (TRV) between baseline and short-term follow-up as predictors for survival. Conclusion: Treprostinil can significantly improve clinical condition, right ventricle function, hemodynamics, and prognosis in children with severe IPAH/HPAH. However, for the children with reduced response to initial treatment non-pharmacological treatments should be considered. Larger, randomized studies using treprostinil in pediatric IPAH/HPAH patients are warranted.
Sequence Spinning Axially Encoded Metafibers
Authors: Ma Jingyu , Liu Yingjun , Gao Chao , Xu Zhen 
Published: March 2023

Abstract

Fiber, an element component of textiles, biology and devices, usually features the same composition and functions along its continuous length. Beyond traditional homogeneous structure, fiber has evolved to the information era and massive codes are expected to be integrated into a single fiber. For the best, encoding fiber along the length direction should reach the maximum code density, however, waits to be fully exploited. Here, we report a microfluidic sequence spinning (MSS) method to continuously program multiple sequencing codes in a single fiber along the axial direction. We precisely controlled the composition arrangement, length and stoichiometric ratio of each sequence. We initiated the axially encoded fiber to encompass mechanical, electrical, magnetic and photothermal metafibers, enabling digitally design metastructure of single fibers. The delicate design in fiber axial compositions conveyed the idea that a single fiber can be digitally programmed to encode and decode information. The axial encoded metafiber extends the scope of fibrous materials and fulfill target demands of future smart textiles.
Effect of Ghrelin on mitophagy in intestinal epithelial cells through the AMPK/FUNDC1 pathway
Authors: Tan Wanyi , Dai Xiaoyong , Ye Youwen , Pang Xiufeng , Jiang Meng , Shi Bin 
Published: March 2023

Abstract
Background

The incidence and fatality rate of intestinal I/R injury are increasing year by year, which is a problem that the medical community has been concerned about and needs to be solved urgently. The aim of this study is to explore the effect of the gastrointestinal hormone Ghrelin on the AMPK/FUNDC1 mitophagy pathway under intestinal ischemia and reperfusion, and to clarify the mechanism of the protective effect of Ghrelin on intestinal epithelial cells.

Method

Adult male SD rats were randomized into four groups: sham surgery (Sham), I/R, I/R + Ghrelin, and I/R + Ghrelin + FUNDC1 antagonist group.A model of intestinal ischemia-reperfusion injury was established by clamped the superior mesenteric artery.Rat intestinal epithelium and lung tissues were taken to observe the histopathological morphology and autophagy activity.To measure the IL-6 test for inflammatory factor levels in intestinal epithelial cells, lung lobes, and peripheral blood by ELISA.The expression levels of autophagy proteins including AMPK, pAMPK, FUNDC1, and LC3 in all the rat intestinal epithelial tissues were determined by Western blot.Intracellular ROS levels were measured by a reactive oxygen species fluorescent probe. Using JC-1 probe to detect mitochondrial membrane potential levels.And the expression was determined by quantitative mtDNA by PCR.

Result

HE staining showed that there was no significant intestinal mucosal damage in Sham group,while intestinal mucosal damage was evident in I/R group.Similarly,the villus structure in the I/R + group was nearly normal but the structural in the I/R + Ghrelin + FUNDC1 antagonist group was like that in I/R group.
Compared with the Sham group, IL-6, ROS, and mtDNA levels were significantly increased while the levels of mitochondrial membrane potential and AMPK, FUNDC1, and LC3 protein expression were decreased in group I/R rats (all P <0.05).
Compared with the I/R group, the oxidative stress was reduced in the I/R + Ghrelin group, with improved mitochondrial energy metabolism and increased mitophagy protein expression (all P <0.05).However, the I/R+Ghrelin+FUNDC1 inhibitor group reversed the protective effect of the I/R+Ghrelin group, and the results of each test index were close to the I/R group (all P <0.05).
Conclusion: Ghrelin can protect against intestinal ischemia and reperfusion injury and distant organs, which may be regulated by the mitophagy pathway of FUNDC1 by AMPK protein.
One case of acute myocardial injury induced pheochromocytoma and paraganglioma
Authors: Xu Shuwan , Ouyang Xilin , Mai Peibiao , Zhang Huanji , Zhang Kun , Jiang Huijie 
Published: March 2023

Abstract
Background
Pheochromocytoma and paraganglioma (PPGL) are neuroendocrine tumors respectively originating from the adrenal medulla and extra-adrenal sympathetic ganglia. The coexistence of pheochromocytoma and paraganglioma is known as composite pheochromocytoma. High levels of catecholamines secreted by PPGL can cause acute myocardial injuries and cardiac dysfunction, such as acute heart failure, pulmonary embolism, cardiogenic shock, and tachyarrhythmia. PPGL is a rare disease. In the clinic, it is easy to ignore or delay diagnosis, resulting in misdiagnosis of patients or untimely treatment.
Case presentation
A 37-year-old woman presented with headache, chest discomfort, and abdominal pain. At the time of the attack, the patient had a maximum blood pressure of 167/90mmHg and a heart rate of 100 beats per minute. Chest computed tomography revealed a mass inside the left adrenal limb. The level of methoxy-catecholamines in the urine sample exceeded the reference values, confirming the diagnosis of adrenal pheochromocytoma. The patient was orally administered adrenergic blockers to relieve symptoms. After a left adrenal mass resection, the plasma catecholamine level was normal, and postoperative medication was discontinued. At the telephone follow-up, the patient complained of occasional episodes of palpitation, but no pain or other discomfort.
Conclusions
We present a case of acute myocardial injury caused by PPGL and conduct a relevant literature review to provide experience for the clinic. In young female patients lacking cardiovascular risk factors presenting with episodes of hypertension and chest tightness, it is recommended to refine CT for the presence of adrenal masses and to rule out circulatory complications promptly. All patients with PPGL are advised to refine genetic testing.
PAPR Suppression in OFDM Systems Using a Combination of FWFT and Nonlinear Root-Based Exponential Companding with Minimum Complexity
Authors: Yadav Ajay Kumar , Prajapati Yogendra 
Published: March 2023

Abstract
The high peak-to-average power ratio (PAPR) of orthogonal frequency division multiplexing (OFDM) system is a major drawback. To tackle this, we recommend a neoteric scheme which is associated with a combination of fast Walsh-Hadamard and Fourier transform (FWFT) of low computing complexity and nonlinear root-based exponential companding (REC). The FWF-transform is being obtained by cascading Walsh-Hadamard transform (WHT) and Fourier transform. The WHT is a linear precoder that distorts phase to somewhat mitigate PAPR. In addition to that, the REC scheme is introduced to further minimize PAPR by adjusting companding parameters. By knowing that conventional exponential companding (EC) increases the low amplitude signals and does not influence high peaks of OFDM signals appropriately. Though, REC scheme does not only compress high amplitudes but also enlarges low amplitudes of the OFDM system simultaneously. Correspondingly, PAPR of the OFDM system reduces. In comparison to any of the other existing schemes, our proposed scheme (FWFT-REC) preserves bit error rate (BER) performance over AWGN, AGWN with solid-state power amplifier (SSPA), and multipath Rayleigh fading channels at the same BER while suppressing PAPR up to 2.10 dB for QPSK at the same complementary cumulative distribution function (CCDF) = 10− 3.
Unveiling the origin of n-type doping of natural MoS2: Carbon
Authors: Park Youngsin , Li Nannan , Jung Daesung , Singh Laishram Tomba , Baik Jaeyoon , Lee Eunsook , Oh Dongseok , Kim Young Dok , Lee Jin Yong , Woo Jeongseok , Park Seungmin , Kim Hanchul , Lee Geunseop , Lee Geunsik , Hwang Chan 
Published: March 2023

Abstract
MoS2 has attracted intense interest for many applications. Natural MoS2 and field-effect transistors made of it generally exhibit n-type characteristics, but its origin is unknown. Herein, we show that C is the origin of the universal n-type doping of natural MoS2. Photoemission spectroscopies reveal that while many MoS2 samples with C detected are n-type, some without C exhibit p-type characteristics. The C-free, p-type MoS2 changes to n-type over time with the concurrent appearance of C that is out-diffused from bulk, indicating that C induces the n-type doping. The C-origin is verified by C-deposition and supported by theoretical calculations. This carbon appears as nanometer-scale defects frequently observed in scanning tunneling microscopy. In addition, we propose based on the calculations that S vacancies are responsible for the p-type characteristics, which contrasts the widespread belief. This work provides new perspectives on MoS2 doping and presents a new direction for fabricating reliable MoS2 devices.
Thermodynamics of multi-sublattice battery active materials: from an extended regular solution theory to a phase-field model of LiMnFe&lt;1-y&gt;PO
Authors: Ombrini Pierfrancesco , Bazant Martin , Wagemaker Marnix , Vasileiadis Alexandros 
Published: March 2023

Abstract
Phase separation during the lithiation of redox-active materials is a critical factor affecting battery performance, including energy density, charging rates, and cycle life. Accurate physical descriptions of these materials are necessary for understanding underlying lithiation mechanisms, performance limitations, and optimizing energy storage devices. This work presents an extended regular solution model that captures mutual interactions between sublattices of multi-sublattice battery materials, typically synthesized by metal substitution. We apply the model to phospho-olivine materials and demonstrate its quantitative accuracy in predicting the composition-dependent redox shift of the plateaus of LiMnyFe1−yPO4 (LFMP), LiCoyFe1−yPO4 (LFCP), LiCoxMnyFe1−x−yPO4 (LFMCP), as well as their phase separation behavior. Furthermore, we develop a phase-field model of LFMP that consistently matches experimental data and identifies LiMn0.4Fe0.6PO4 as a superior composition that favors a solid solution phase transition, making it ideal for high-power applications.
Novel chuvirus detected in a solitary wild bee species (Osmia taurus) from Japan
Authors: Takemae Hitoshi , Nunomura Yuka , Yokota Tomoko , Oba Mami , Mizutani Tetsuya , Hsu Wei-Li , Sakamoto Yoshiko 
Published: March 2023

Abstract
Pathogens of wild bees in Japan remain largely unknown. We examined viruses harbored by solitary wild Osmia bees, including Osmia cornifrons and Osmia taurus. Interestingly, full length genome of a novel virus (designated Osmia-associated bee chuvirus, OABV) were identified from 3 Osmia taurus bees collected in Fukushima prefecture. The sequences and genomic features are similar to those of the Scaldis River bee virus. Phylogenetic analysis indicated the glycoprotein and nucleoprotein of OABV forms a subcluster within arthropod chuviruses, and close to those strains identified from European countries. Study herein extended the current knowledge of wild bee parasite in Japan.