bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robust laser ablation Lu–Hf dating of apatite: an empirical evaluation
Authors: Glorie Stijn , Hand Martin , Mulder Jacob , Simpson Alexander , Emo Robert B. , Kamber Balz , Fernie Nicholas , Nixon Angus , Gilbert Sarah 
Published: January 2023

Abstract

Recent developments in laser-ablation Lu–Hf dating have opened a new opportunity to rapidly obtain apatite ages that are potentially more robust to isotopic resetting compared to traditional U–Pb dating. However, the robustness of the apatite Lu–Hf system has not been systematically examined. To address this knowledge gap, we conducted four case studies to determine the resistivity of the apatite Lu–Hf system compared to the zircon and apatite U–Pb system. In all cases, the apatite U–Pb system records a secondary (metamorphic or metasomatic) overprint. The apatite Lu–Hf system, however, preserves primary crystallization ages in unfoliated granitoids at temperatures of at least
c.
660°C. Above
c.
730°C, the Lu–Hf system records isotopic resetting by volume diffusion. Hence, in our observations for apatites of ‘typical’ grain sizes in granitoids (
c.
0.01–0.03 mm
2
), the closure temperature of the Lu–Hf system is between
c.
660 and
c.
730°C, consistent with theoretical calculations. In foliated granites, the Lu–Hf system records the timing of recrystallization, while the apatite U–Pb system tends to record younger cooling ages. We also present apatite Lu–Hf dates for lower crustal xenoliths erupted with young alkali basalts, demonstrating that the Lu–Hf system can retain a memory of primary ages when exposed to magmatic temperatures for a relatively short duration. Hence, the apatite Lu–Hf system is a new insightful addition to traditional zircon (or monazite) U–Pb dating, particularly when zircons/monazites are absent or difficult to interpret due to inheritance or when U and Pb isotopes display open system behaviour. The laser-ablation-based Lu–Hf method allows campaign-style studies to be conducted at a similar rate to U–Pb studies, opening new opportunities for magmatic and metamorphic studies.
Introduction to the Special Section on Selected Papers from ICCPS 2021
Authors: Al Faruque Mohammad , Oishi Meeko Mitsuko 
Published: January 2023

The articles in this special section are based on selected papers presented at the 2021 ACM/IEEE International Conference on Cyber-Physical Systems (ICCPS 2021), a premier single-track conference that promotes development of fundamental principles that underpin the integration of cyber and physical elements, as well as the development of technologies, tools, architectures, and infrastructure for the design and implementation of CPS. ICCPS 2021 focused on contributions related to smart and connected cities, autonomous CPS, verification and control, security and privacy, and human health and biomedical CPS.
Methicillin-Resistant and Biofilm-Producing Staphylococcus aureus in Nasal Carriage among Health Care Workers and Medical Students
Authors: Saud Bhuvan , Khatri Gita , Amatya Neetu , Paudel Govinda , Shrestha Vikram 
Published: January 2023

Antimicrobial resistance (AMR) is a global threat. It has been portrayed as a slow tsunami. Multidrug resistance and extensive drug resistance exacerbate the already-existing AMR problem. The aim of the study was to access the colonization of methicillin-resistant and biofilm-producing Staphylococcus aureus among healthcare workers (HCWs) and medical students (MSs). A cross-sectional study was designed. A total of 352 participants (176 were HCWs and 176 were MSs) were enrolled from different hospitals and medical colleges in Kathmandu, Nepal. Nasal cavity swab samples were collected and inoculated on Mannitol salt agar at standard in-vitro environmental conditions. Isolates were identified based on colony characteristics, staining properties, and biochemical tests. Identified isolates were tested for antibiotic susceptibility and biofilm production. Out of 352 participants, 65.3% were S. aureus carriers; among the carriers, 52.2% were HCWs and 47.8% were MSs. Of the total isolates, 47.4% isolates were methicillin-resistant S. aureus (MRSA) and 73.9% isolates were multidrug-resistant (MDR). Among MDR isolates, out of 109 MRSA isolates, 86.2% were MDR and out of 121 MSSA isolates, 62.8% were MDR where isolates were mainly resistant to erythromycin. In addition, 68.7% isolates were biofilm-forming; the results were similar in both MRSA and MSSA. Variables such as profession and educational level showed statistical significance (

p

< 0.05) with MRSA, MSSA, and biofilm producers. In conclusion, asymptomatic colonization of healthcare workers by drug-resistant S. aureus is increasing at alarming rates. This reflects the lack of proper hygiene practice as well as improper disinfection of workplace of study population.
Performance Optimization of Slotted Blades for Low-Specific Speed Centrifugal Pumps
Authors: Ke Qidi , Tang Lingfeng 
Published: January 2023

Centrifugal pumps are widely used for the transport of fluids, but low-specific-speed centrifugal pumps widely have problems with serious backflow and low efficiency. In this paper, a low-specific-speed centrifugal pump with a specific speed of 55 is used as a research object. By combining numerical simulation and orthogonal experiment, the pressure distribution and velocity distribution of the flow channel are analyzed, the priority of each geometric factor for slits on pump performance is determined, the geometric parameter structure of the slotted blade is optimized by entropy weight on TOPSIS, the optimal impeller slit solution is obtained. The results show that with a balance of head and efficiency, the order of influence of the factors is: slit center width

b
>

diameter of slit

D
>

shrinkage ratio of slit

f
>

depth of slit

h
>

deflection angle of slit

β

. The optimal combination of slit geometry parameters is: slit center width is 3

m
m

, diameter of the slit is 200

m
m

, shrinkage ratio of the slit is 0.5, depth of the slit is 6

m
m

, and the deflection angle of the slit is 20°. Through ANSYS FLUENT simulation and experiment of closed pump experiment system, confirmed that hydraulic performance is improved.
Grade 11 Students’ Multiple Intelligences: Inputs Towards Developing and Evaluating Technologically-Mediated Learning Materials on Discourse Development Patterns
Authors: Discutido Roy A. 
Published: January 2023

Learners around the world possess varying degrees of intelligence. With that, teachers should be aware of the multiple intelligence of the learners to consider them when preparing teaching materials or classroom activities. This is to aid the deteriorating performance of the learners specifically in language learning. As seen in the results of international assessments or even in national achievement tests, learners showed that they were not able to master the required competencies and one of the reasons is the ability to comprehend. This study aimed to determine the extent of use of the multiple intelligences of the Grade 11 students of Cainta Senior High School in the Division of Rizal which served as inputs in developing and evaluating technologically-mediated learning materials on discourse development patterns during the school year 2020-2021. With two groups of respondents, the students and the teachers, the developed material based on the multiple intelligence of the learners was evaluated in terms of authenticity, automaticity, clarity, comprehensibility, meaningfulness, and technicality. Using t-test, the gathered data was treated. The results revealed that there is no significant difference between the evaluation of students and teacher respondents whom both said that the technologically-mediated language learning material is very highly acceptable for teaching and learning the different discourse development patterns using the students’ multiple intelligences.
Selected Profile and Factors Affecting the Academic Performance in Social Studies of Grade 10 Students: Input for an Intervention Program
Authors: Nicolas Rowena E. 
Published: January 2023

Education is deemed to be an important tool for social mobility. Because of this, quality education is one of the many goals of Filipinos who wanted to have an improvement in their lives. However, one major issue in Philippine education is the poor academic performance of the students. Thus, this paper focuses on the profile of selected Grade 10 students of Bagong Silangan High School and its impact on their academic performance in Social Studies. The study utilized a descriptive research design. Pearson correlational statistical analysis was done to determine the relationship among variables. Results showed that most of the student respondents’ parents were high school graduates (43.81%), do not have occupation (57.78%), have family monthly income ranging from 10,000-19,999 (43.17%) and have 3 siblings (25.40%). Results also revealed that the extent of the factors affecting the academic performance of students in Social Studies in terms of teachers’ competency, learning environment, parents’ aspiration, student-parents relationship and peer relationship are all high. In addition, there is a moderate positive and negative correlation between the factors affecting the academic performance of students and their academic performance in Social Studies in terms of teachers’ competency, parents’ occupation, learning environment and peer relationship with Pearson r’s of 0.015,0.403, - 0.069 and -5984. An intervention program was recommended and prepared based on the results of the study.
Prevalence of Burnout Among Health Care Workers at Dr. Saiful Anwar General Hospital During COVID-19 Pandemic: A Cross-Sectional Study
Authors: Daryanto Besut , Putri Frilya Rachma , Kurniawan Jemmy , Ilmawan Muhammad , Fajar Jonny Karunia 
Published: January 2023

Pendahuluan: Sebagai garda terdepan dalam penanganan COVID-19, tenaga kesehatan merupakan salah satu pihak yang paling terdampak oleh pandemi COVID-19. Menghadapi berbagai macam tantangan, seperti risiko tertular dan menularkan virus, tenaga kesehatan memiliki risiko lebih besar untuk mengalami burnout.
Tujuan: Penelitian ini bertujuan untuk melihat prevalensi burnout beserta faktor yang berasosiasi terhadap burnout pada tenaga kesehatan di Rumah Sakit Umum Daerah Dr. Saiful Anwar (RSSA) selama pandemi COVID-19.
Metode: Penelitian ini menggunakan desain studi potong-lintang dengan menggunakan kuesioner yang disebarkan secara daring kepada seluruh tenaga kesehatan di RSSA. Penilaian burnout menggunakan Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Asosiasi dianalisis menggunakan regresi logistik dan disajikan dalam odds ratio (OR) dengan confidence interval 95% (CI 95%).
Hasil: Sebanyak 444 tenaga kesehatan di RSSA ikut serta dalam penelitian ini. Sebanyak 21,6% dari seluruh partisipan mengalami burnout. Partisipan dengan usia >40 tahun memiliki risiko 3,7 kali lebih rendah mengalami burnout dibandingkan dengan yang berusia <30 tahun. Sedangkan partisipan yang bekerja 70-100 dan >100 jam per minggu, masing-masing memiliki risiko 2,4 dan 4,5 kali lipat lebih tinggi dibandingkan dengan yang bekerja <70 jam per minggu.
Kesimpulan: Hampir seperlima tenaga kesehatan di RSSA mengalami burnout selama pandemi COVID-19, terutama mereka yang berusia <30 tahun dan bekerja >70 jam per minggu.
Evaluasi Profil kuman dan Sensitivitas Antibiotik dari Pasien Pneumonia selama Setahun di RSUD. Saiful Anwar Malang
Authors: Tantular Rezki , Jane Sugiri , Andreas Santoso , Kristo Kurniawan , Yusuf Mustofa , Abdul Haris 
Published: January 2023

Pendahuluan: Pneumonia adalah infeksi pada jaringan paru(alveoli) yang disebabkan oleh bakteria,virus atau jamur
Metode: Studi retrospektif di Rumah Sakit Saiful Anwar Malang pada bulan Januari – Mei 2019. Sampel yang digunakan adalah sampel sputum, spesimen bronkoskopi dan cairan pleura dari pasien pneumonia pada Instalasi Rawat Inap, Rawat Jalan, dan Ruang Perawatan Intensif. Pengolahan data menggunakan Microsoft Excel 2016.
Hasil: Pneumonia lebih sering terjadi pada laki-laki (58%) dibandingkan perempuan (42%) dengan rata-rata usia 56- 75 tahun. Profil kuman didapatkan patogen terbanyak pada sputum dari Instalasi Rawat Inap adalah Klebsiella pneumoniae ss. pneumoniae sensitif Piperacillin/Tazobactam (sensitivitas 100%); dari Rawat Jalan adalah Klebsiella pneumoniae ss. pneumoniae sensitif Amikacin (sensitivitas 100%); dari Ruang Perawatan Intensif adalah Klebsiella pneumoniae ss. pneumoniae sensitif Ceftazidim (sensitivitas 100%).
Kesimpulan: Patogen terbanyak pada sampel dari Instalasi Rawat Jalan adalah Klebsiella pneumoniae ss. pneumoniae sensitif Ertapenem (sensitivitas 100%) sedangkan dari Ruang Perawatan Intensif adalah Pseudomonas aeruginosa spesimen bronkoskopi. Patogen terbanyak pada cairan pleura dari Instalasi Rawat Inap adalah Pseudomonas aeruginosa sedangkan dari Ruang Perawatan Intensif adalah Escherichia coli. Tidak dapat dilakukan uji sensitivitas antibiotik pada isolat sampel spesimen bronkoskopi dari Instalasi Rawat Jalan, sampel cairan pleura dari Instalasi Rawat Inap serta Perawatan Intensif karena jumlah isolat yang kurang dari 30.
Baseline Characteristics of Pediatric Patients With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction in the PANORAMA-HF Trial
Authors: Shaddy Robert , Burch Michael , Kantor Paul F. , Solar-Yohay Susan , Garito Tania , Zhang Sijia , Kocun Michele , Bonnet Damien 
Published: January 2023

Background:
Sacubitril/valsartan has been approved for the management of heart failure (HF) with reduced ejection fraction in adults. PANORAMA-HF trial (Prospective Trial to Assess the Angiotensin Receptor Blocker Neprilysin Inhibitor LCZ696 Versus Angiotensin-Converting Enzyme Inhibitor for the Medical Treatment of Pediatric HF) investigated its effects on clinical outcomes in pediatric patients with HF.

Methods:
PANORAMA-HF is a multicenter, Phase II/III study using an adaptive, seamless, 2-part design. The study aimed to evaluate the pharmacokinetics and pharmacodynamics of single doses of sacubitril/valsartan (Part 1), and the efficacy and safety of sacubitril/valsartan versus enalapril administered twice daily for 52 weeks (Part 2) in pediatric patients with HF due to left ventricular systolic dysfunction with biventricular heart physiology. An innovative trial design using a novel global rank assessment of severity was employed. For analysis, eligible patients were stratified into 3 age groups (Group 1, 6 to <18 years; Group 2a, 2 to <6 years; and Group 3a, 1 month to <2 years) and functional classification (New York Heart Association/Ross class I/II and III/IV).

Results:
We report the key demographic, baseline, and clinical characteristics of 375 pediatric patients randomized to receive the study medication. The mean age for patients in Groups 1, 2a, and 3a was 12.2, 3.2, and 1.3 years, respectively. About 70% of patients had a prior HF hospitalization, 85% had New York Heart Association/Ross class I/II HF, and ≈8% were angiotensin-converting enzyme inhibitor/angiotensin receptor blocker naïve.

Conclusions:
Compared to other pediatric HF studies, PANORAMA-HF recruited a relatively homogeneous pediatric HF population across 3 age groups, enabling a more robust evaluation of pharmacokinetics/pharmacodynamics and efficacy/safety of sacubitril/valsartan. Most patients had mildly symptomatic HF at baseline.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02678312.
Pilgrimage Space, Hinduization of Space, Hindutva Politics of Space, and the Case of Ayodhyā as a Religious and Religiopolitical Hotspot
Authors: Jacobsen Knut A. 
Published: January 2023

Abstract
In this article I analyze aspects of religious geography in the mobilization by Hindu nationalists in India in the 1980s and 1990s and how Hindu nationalism and Hindu religious geography were merged in the case of the Ayodhyā conflict. Ayodhyā was consciously changed from a pilgrimage center (tīrtha) of diminishing religious importance into a religiopolitical hotspot by political forces. The potential for a Hindu–Muslim conflict and for mobilizing support for their vision of a Hinduized India was probably what made the place attractive for Hindu nationalists. The article argues that Hindu nationalism exploited the views of territoriality of traditions of pilgrimage and salvific space and merged these with their political nationalist agenda, and that it was this blending of views of space from the pilgrimage traditions, ideas of national territory, and Hindu nationalists’ ideas of a homogeneous Hindu nation with aggressive political agitation that turned Ayodhyā into a religiopolitical hotspot.
Locality Bias Effect and Interpretation of Thai Reflexive Anaphors
Authors: Supwatanapaisan Gazidate , Ratitamkul Theeraporn 
Published: January 2023

Abstract
The two forms of Thai reflexive anaphors, tuaɁeeŋ ‘self’ and tua+pronoun+Ɂeeŋ ‘pronoun-self’, have been claimed to exhibit different referential patterns. While tuaɁeeŋ only co-refers with a local antecedent np within the same clause, tua+pronoun+Ɂeeŋ can refer to both local and distant antecedent np s. In this study, a self-paced reading experiment was used to examine whether and how Locality Bias guided the comprehenders’ online interpretation of tuaɁeeŋ and tua+pronoun+Ɂeeŋ. Our results showed that the reading time was significantly faster when a reflexive anaphor referred to a local np than when it did to a a distant np, regardless of the forms. This suggests that a local antecedent was preferred for both types of reflexives manifesting locality bias effect. Post hoc tests revealed that tua+pronoun+Ɂeeŋ appeared to be more sensitive to the locality bias than tuaɁeeŋ. This may result from the presence of the personal feature in tua+pronoun+Ɂeeŋ, which could restrict reference to local antecedents.
Connecting Ships: Using Dendrochronological Network Analysis to Determine the Wood Provenance of Roman-Period River Barges Found in the Lower Rhine Region and Visualise Wood Use Patterns
Authors: Visser Ronald M. , Vorst Yardeni 
Published: January 2023

Abstract
This study combines standard dendrochronological analyses with network science and spatial analysis to determine the provenance of wood used to build river barges in the Roman period. The river barges studied were found in the Lower Rhine region and would have carried bulk goods, such as grain, military supplies, and building materials. The importance of these vessels in the supply of the local economy and military units is evident since many were found in the area, including some in the vicinity of military complexes. However, it remains unknown where these ships were built and how and where the raw materials for their construction were obtained. To better understand the provenance of the wood, network science was applied to visualise and understand the complex patterns of similarity between the tree-ring curves. For the interpretation of the networks we have studied the context, the position of the trees in the network and the use of these trees in shipbuilding. In addition, the shape of the converted timber was used to visualise the wood use patterns in this type of Roman-period shipbuilding. For the river barges, we were able to determine several possible regions for wood procurement. Based on the analysed material, we assume that there was at least one shipyard in the Lower Rhine region where two ships, found in separate excavations, were most likely produced at the same time.
Upper-Oceanic Warming in the Gulf of Mexico between 1950 and 2020
Authors: Wang Zhankun , Boyer Tim , Reagan James , Hogan Patrick 
Published: January 2023

Abstract
We estimate ocean heat content (OHC) change in the upper 2000 m in the Gulf of Mexico (GOM) from 1950 to 2020 to improve understanding of regional warming. Our estimates are based on 192 890 temperature profiles from the World Ocean Database. Warming occurs at all depths and in most regions except for a small region at northeastern GOM between 200 and 600 m. GOM OHC in the upper 2000 m increases at a rate of 0.38 ± 0.13 ZJ decade−1 between 1970 and 2020, which is equivalent to 1.21 ± 0.41 terawatts (TW). The GOM sea surface temperature (SST) increased ∼1.0° ± 0.25°C between 1970 and 2020, equivalent to a warming rate of 0.19° ± 0.05°C decade−1. Although SST in the GOM increases at a rate approximately twice that for the global ocean, the full-depth ocean heat storage rate in the GOM (0.86 ± 0.26 W m−2) applied to the entire GOM surface is comparable to that for the global ocean (0.82–1.11 W m−2). The upper-1000-m layer accounts for approximately 80%–90% of the total warming and variations in the upper 2000 m in the GOM. The Loop Current advective net heat flux is estimated to be 40.7 ± 6.3 TW through the GOM. A heat budget analysis shows the difference between the advective heat flux and the ocean heat storage rate (1.76 ± 1.36 TW, 1992–2017) can be roughly balanced with the annual net surface heat flux from ECCO (−37.9 TW).
Glycated albumin and post-transplant diabetes mellitus in kidney transplant recipients
Authors: Bleskestad Inger H , Skadberg Øyvind , Åsberg Anders , Gøransson Lasse G 
Published: January 2023

Background Post-transplant diabetes mellitus is one of the most important cardiovascular risk factors after solid organ transplantation. Factors other than hyperglycaemia found in patients post-transplant, affect the level of haemoglobin A1c (HbA1c), and new markers of hyperglycaemia are needed. Our aim was to establish a 95% reference interval for glycated albumin in kidney transplant recipients, and to compare glycated albumin concentrations to the diagnostic criteria for diabetes mellitus post-transplant using oral glucose tolerance test and HbA1c. Methods A total of 341 non-diabetic kidney transplant recipients aged ≥18 years who underwent an oral glucose tolerance test at 8 weeks and 1 year after transplantation were included. Glycated albumin was determined by liquid chromatography coupled with tandem mass spectrometry. Results The 95% reference interval for glycated albumin was 8.2 (90% CI: 7.2–8.5) to 12.8% (90% CI: 12.2–13.5) which is not significantly different from our laboratory’s 95% reference interval for persons without diabetes. At both 8 weeks and 1 year after transplantation, 35 patients (10.3%) fulfilled one, two or all three diagnostic criteria for diabetes mellitus. One year after transplantation, eight additional patients had glycated albumin concentration >12.8%. Conclusion Our findings are in accordance with the notion that kidney transplant recipients form glycation end products like normal controls as estimated by glycated albumin and HbA1c. Further studies should address glycated albumin as a supplemental tool for the diagnosis of post-transplant diabetes mellitus in kidney transplant recipients.