bluuebunny/crossref_metadata_2025_split huggingface dataset:
The usefulness of arylesterase in predicting contrast-induced nephropathy in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention
Authors: KALAYCI Süleyman , HAMAMCIOGLU Ayse Ceylan , KALAYCI Belma 
Published: April 2023

Aim: Oxidative stress is one of the causes of contrast-induced nephropathy (CIN). Paraoxonase1 (PON1), is one of the oxidative stress markers. The most sensitive method that has been in use to measure PON1 enzyme activity is the measurement of arylesterase (AREase) activity. To explore relationship between AREase activity and CIN development.
Material and Method: A total of 58 STEMI patients were included in our study. The patients were divided into two groups as CIN (+) and CIN (-). The success of AREase activity level in predicting the development of CIN was also examined by using ROC analysis.
Results: Out of the study patients, 13 were CIN (+) and 45 were CIN (-). AREase activity was found to be statistically significantly lower in the CIN (+) group (875 U/L vs 819 U/L, p= 0.004). In the regression analysis, diabetes mellitus, contrast volume and AREase activity were determined as independent risk factors in the development of CIN. As a result of the ROC analysis, we concluded that the AREase activity level
Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemorrhage
Authors: KOCATÜRK İdris , GÜLTEN Sedat 
Published: April 2023

Aim: This study aims to evaluate immature granulocyte count (IG#) and percentage (IG%) in the prediction of mortality in spontaneous intracerebral hemorrhage (SICH).
Material and Method: Demographic characteristics and laboratory test results of patients diagnosed with SICH and admitted to the neurology clinic in a tertiary hospital between January 1, 2020, and January 1, 2022, were recorded. One hundred ten patients were included in the study. While 80 of these patients constituted the group that recovered after treatment, 30 of them formed the group that died despite treatment. IG and other laboratory and clinic parameters were statistically compared in both groups.
Results: Of 110 patients, 45 (42.7%) were female, and 65 (57.3%) were male. IG counts were higher in the non-survival group than in the survival group (p=0.001). When the patients were divided according to low IG% (=0.6), 30 patients were in the high IG# group, and 80 patients were in the low IG% group. White blood cell (WBC), neutrophil count (NEUT#), monocyte count (MONO#), IG#, neutrophil-lymphocyte ratio (NLR), and hemorrhage volume (HV) values were statistically significantly higher in the high IG% group than in the low IG% group; Glasgow coma score (GCS) and percentage of lymphocytes (LYMPH%) values were significantly lower too. In addition, the mortality rate in the high IG# group was significantly higher than the mortality rate in the low IG% group (53.23% vs. 17.5%).
Conclusion: IG is a new, easily accessible, inexpensive, and promising marker for predicting in-hospital mortality in patients with SICH.
Evaluation of osteoporosis knowledge level of women who applied to the family medicine outpatient clinics of a university hospital
Authors: BİRİNCİ OCAK Bahar , CEYHUN PEKER Ayşe Gülsen , DAĞDEVİREN Murat 
Published: April 2023

Aim: This study aimed to assess the knowledge, attitude, and behavior of women aged 18–45 years toward osteoporosis.
Material and Method: A total of 368 females (average age:32.59±7.58) who applied to the family medicine outpatient clinics between 15 May 2016 and 15 August 2016 participated in this study. Participants completed the revised osteoporosis knowledge test, which contained 12 socio-demographic questions.
Results: The average score for participants in the exercise subgroup was found to be 9.56±3.62 out of 20; the average score for the nutrition subgroup was 12.86±4.17 out of 26, and the average total score was 15.08 ± 4.82 out of 32. In general, the average score of participants was found to be 50% percent or less of the maximum scores of each subgroup of the questionnaire. This result suggests that women have inadequate knowledge about osteoporosis. Participants’ level of knowledge of osteoporosis was related to their education levels, occupational groups, and smoking status. High educational levels of participants correlated with high average scores (p
A comparative study of the effects of chronic kidney disease on sonographic arterial stiffness parameters in geriatric and normal population
Authors: DOĞAN Kamil , BAYKARA Murat , ÖZTÜRK Cansu 
Published: April 2023

Aim: Due to its growing incidence rate worldwide, chronic kidney disease is a crucial public health problem which is strongly associated with cardiovascular disease. Cardiovascular disease in chronic kidney disease patients is characterized by arteriosclerosis and increased arterial stiffness, and is the leading cause of morbidity and mortality. A correlation was reported between an increased arterial stiffness and cardiovascular disease in high risk groups such as chronic kidney disease or hypertension as well as general undiagnosed population. Our aim was to show the changes in arterial stiffness parameters in patients with chronic kidney disease in the geriatric population.
Material and Method: 44 chronic kidney disease patients and 44 control group cases of the same age were included in the study. There were 20 female and 24 male cases in each group. Systolic and diastolic diameter were measured for all cases. Intima-media thickness was measured in carotid and femoral arteries. Arterial stiffness parameters were calculated using formulas. Systolic and diastolic arterial blood pressure and body mass index were measured. Their urea and creatinine values were recorded.
Results: There were no differences between two groups in terms of age and sex (p=0.069). Body mass index in the patient group was significantly lower compared to the control group (p=0.025). Systolic arterial blood pressure was higher in the patient group (p
Correlations of renal parenchymal attenuations and CT severity scores on three consecutive CTs in COVID-19 patients
Authors: KAYA Ahmet Turan , AKMAN Burcu 
Published: April 2023

Aim: We aimed to investigate the correlation between the temporal changes of computed tomography severity score (CT-SS) ​​and mean renal parenchymal attenuation (MRPA) values in consecutive chest computed topographies (CT).
Material and Method: This retrospective, single-center study included 65 (≥18 years) COVID-19 patients with positive RT-PCR tests. A radiologist calculated three consecutive chest CT-SSs and measured the MPRAs on CTs from the upper half of each kidney included in the cross-section. Paired samples test and Wilcoxon signed-rank test were used to evaluate the temporal changes of mean renal parenchymal attenuation (RPA) and median CT-SS values, in three consecutive CTs. Spearman's test was used to evaluate the correlation of each RPA and CT-SS value on three consecutive CTs.
Results: The study population included 65 patients with a mean age of 61.49±13.91 years. A total of 36/65 (55.4%) were male. We found a significant increase between the first and second CT-SS (p
Role of systemic immune-inflammation index in predicting mortality in cancer patients in palliative care units
Authors: TUTAN Duygu , ESKİN Fatih 
Published: April 2023

Aim: In our study, we aimed to investigate whether the systemic immune-inflammation index (SII) can evaluate mortality in cancer patients treated in the palliative care unit (PCU).
Material and Method: Cancer patients who received palliative care treatments in the PCU were screened retrospectively, and 309 patients were included in the study. The patients were divided into two groups; hospitalizations ending with discharge as Group 1 (n=154) and hospitalizations ending with exitus as Group 2 (n=155). SII values of the two groups were compared. SII was calculated with the formula of neutrophil count x platelet count / lymphocyte count. To determine the best cut-off value for the mortality distinction ability of the SII, a Receiver Operating Curve (ROC) analysis was used.
Results: The mean age and distribution of genders of the two groups were similar (p=0.706, p=0.964). There was a statistically significant difference between the SII values of the two groups (p
Current treatment approaches of newly graduated, intern dentists and dentists in doctoral and specialty training to teeth with excessive substance loss (cross-sectional study)
Authors: ALTAN Bike , FİLDİŞİ Mehmet Ali , ÇINAR Şevki , AYDEMİR Elifnur , ÖZKAN Davut 
Published: April 2023

Aim: New treatment options have been developed as alternative post-retaining restorations and crowns that preserve remaining tooth tissue in endodontically treated teeth with excessive substance loss. This study, current treatment approaches newly graduated, intern and doctoral or specialist dentists in teeth excessive coronal destruction were evaluated.
Material and Method: This cross-sectional study, online questionnaire consisting of 22 questions, 3 parts was applied. First part consists of demographic information participants, second part consists of questions measuring awareness about preferred indirect restorations, last part consists of current treatment approaches newly graduated, intern and doctoral or specialist dentists. Total 234 voluntary participants questionnaires were evaluated. Obtained data were analyzed with IBM SPSS V23.
Results: In restoration of endodontically treated buccal mesial walls (least 2 mm thick) molars, participants all 3 groups preferred posterior adhesive indirect restorations according to their titles. Considering level of awareness, participants high group preferred posterior adhesive indirect restorations more in restorations endodontically treated buccal lingual walled molar teeth. Participants all 3 groups preferred use fiber under composite strengthen teeth in the restoration of teeth with excessive substance loss.
Conclusion: According to the results, it was determined that awareness and knowledge level of dentists who received specialty or doctoral training about new current treatments was higher than other newly graduated and intern dentists. It was observed that participants group with high level awareness mostly preferred posterior region indirect adhesive restorations such as endocrown and onlay.
Does YouTube™ give us accurate information about bruxism?
Authors: BİLİR Halenur , YILANCI Hilal 
Published: April 2023

Aim: The aim of this study is to evaluate the quality of the information provided by the most watched videos about bruxism on YouTube™.
Material and Method: The results of YouTube™search were examined using the keyword “bruxism”. The searching limited to the first 130 videos. DISCERN and the video information and quality index (VIQI) and the criteria were used for evaluating the videos. Also, the interaction index and the viewing rate of the videos were calculated. The Kruskal-Wallis H Test, Pearson's Chi-Square Test, Spearman's rho correlation were used for statistical analyses. Significance level was taken as p
Predictive value of inflammatory markers in gastric cancer
Authors: BAŞÇEKEN Salim İlksen , TİKİCİ Deniz 
Published: April 2023

Aim: Many recent studies are increasingly shedding light on the nature of the relationship between cancer and inflammation. Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) platelet/neutrophil ratio (PNR), and Mean Platelet Volume (MPV) are proinflammatory markers, and their prognostic importance has been investigated in many solid cancers. In this study, we discussed the association of these derivative inflammatory markers, obtained from a cheap and simple peripheral blood test, with clinicopathologic variables in patients undergoing gastrectomy for gastric cancer.
Material and Method: The retrospective database of a total of 148 patients who were operated for gastric cancer in the Diyarbakır Gazi Yaşargil Training and Research Hospital Department of Surgery was analyzed. All blood results and pathology reports of the patients were reviewed retrospectively. Demographic characteristics of the patients and pathological features of the tumor were extracted from the database. NLR, PLR, PNR and MPV values were calculated from peripheral blood cell counts. Data were analyzed using SPSS version 24.0.
Results: PNR and MPV values were statistically significant according to N and T stage of the tumor, respectively (p=0.035, p=0.011). In MPV, this difference was statistically observed between T1 and T2 tumors (p=0.029). PLR and NLR values did not show a significant difference according to the size of the tumor (p>.05).
Conclusion: MPV values are significantly associated with tumor T stage. PNR values are significantly associated with tumor N stage. However, the clinical implications and the added value to clinical practice require further research.
Analysis of perinatal outcomes of pregnancies from consanguineous marriages in a tertiary hospital in Bursa, Turkey
Authors: KARAŞİN Süleyman Serkan , KAZANCI Elif Güler , PAKAY Kaan , ÖZYAMACI Berin , TÜYSÜZ Tuba Nur , ESEN Şeniz Kurtoğlu , TURANLI Cansel Ezgi 
Published: April 2023

Aim: In this article, we aimed to contribute to the outcomes of the consanguineous marriage literature by analyzing fetal results in this population.
Material and Method: We included 185 patients in this retrospective research. Demographic, clinical, ultrasonographic and delivery data were received from electronic patient records. Also, we recorded the postnatal results, and findings of the infants. By combining all the data, we reported a descriptive analysis of the results of our consanguineous marriage cases with perinatology follow-up.
Results: We had 231 pregnant women in the study, and their mean age was 28.9 years. 117 (50.6%) of the pregnant women had first-degree, and 114 (50.4%) had second-degree consanguineous marriages. Fetal findings were evaluated as usual in 157 (68%) of the pregnant in the ultrasonographic scans performed between prenatal 20-24 weeks of gestation. When we look at the first postnatal examinations of the babies, no abnormal findings were in 134 babies (58.8%). Twenty-two infants (9.6%) were followed up in the neonatal intensive care unit with the diagnosis of transient tachypnea of the newborn, and phototherapy was required in 14 infants (6.1%) due to hyperbilirubinemia. The number of cases requiring surgical intervention after delivery or with significant life-threatening anomalies included 56 findings in 32 infants. There were spina bifida cases in 8 infants and hydrocephalus in 9 infants.
Conclusion: There was an increased level of congenital anomalies associated with consanguineous marriages. Health care centers should educate individuals regarding the negative role of cousin marriages leading to abnormalities in children.
Risk factors for hypocalcemia and correlation between thyroid volume and incidental parathyroidectomy after total thyroidectomy: single center experience
Authors: ŞIVGIN Hakan , BOSTAN Mustafa Sami 
Published: April 2023

Aim: We aimed to investigate correlation between the effects of age, sex, disease, pathologic diagnosis, parathyroid autotransplantation, presence of parathyroid in the pathology specimen and clinicopathological variables and thyroid volume, postoperative hypocalcemia after bilateral total thyroidectomy.
Material and Method: A retrospective study planned in tertiary university hospital on patients undergone bilateral total thyroidectomy and neck dissection when necessary surgery for thyroid pathologies. Minimum calcium values in the postoperative period were recorded as transient or permanent hypocalcemia. The cases were statistically analyzed for the relationship between the volume of the thyroid gland removed and hypocalcemia. The effects of sex, pathological diagnosis, preoperative hyperthyroidism, anatomical retrosternal extension, number of parathyroid glands seen and preserved intraoperatively, parathyroid gland autoimplantation, parathyroid gland removal in the pathological specimen, nerve monitoring, bilateral total thyroidectomy and central and lateral neck dissection were analyzed for postoperative hypocalcemia.
Results: Totally 763 patients were included in the study. The mean age of the patients was 50.6 years (SD:12.8) and the sex of 575 (75.4%) patients was female. Hypocalcemia was more common in women than in men (31% vs 17%; p
Sloped marginal configuration design of implants as an alternative innovation to the grafting operations: a three-dimensional finite element analysis
Authors: TOPRAK Mehmet Emin 
Published: April 2023

Aim: Dental implant operations often require bone grafting due to bone resorption in the buccal area, which make the treatment more complicated, increase the risk of complications, and results in extra costs and prolongation of treatment. This study aimed to evaluate the biomechanical behavior of the implants with a sloped marginal configuration design in the alveolar ridge with a level difference between the buccal and lingual bone levels using three-dimensional finite element analysis (FEA) method.
Material and Method: Two implant models with different marginal configuration designs were used in this study. Implants were placed in the posterior edentulous mandible models in which the buccal region had a 2 mm more resorption according to lingual region which were created by imitating natural bone resorption with FEA. Bone grafting was performed on the exposed buccal surface in the conventional flat marginal configuration implant model (Model 1). In contrast, the sloped marginal configuration implants were compatible with the difference in bone level and placed directly without any additional surgical procedures (Model 2). Than three unit fixed partial dentures were designed. The design of cortical and cancellous bones, prosthetic components, implants, abutment screws and abutments covering those in the edentulous mandible models were transferred to digital three-dimensional models that were created to mimicking the real structures. The models were fixed below and behind of the mandible with zero movement. Load transfer characteristics of both models under these essential limitations were evaluated under 200N foodstuff force.
Results: The highest von Mises stress value was observed as 69.300 MPa in Model 1 and 126.870 MPa in Model 2. The maximum principal stress values were 28.236 N/mm2 and 63.449 N/mm2; the minimum principal stress values were 38.346 N/mm2 and 43.643 N/mm2 in Model 1 and Model 2, respectively. The highest von Mises stress value, maximum principal stress and minimum principal stress values were found higher in Model 2 which was created with sloped marginal configuration design of implants but all values were observed within acceptable physiological limits.
Conclusion: The sloped marginal configuration design of implants can be a non-invasive and more economical treatment alternative modality compared to conventional flat marginal configuration implants with advanced surgeries during implant placement.
Evaluation of cases with early repolarization on electrocardiogram and normal population in terms of laboratory and clinical results
Authors: ÖZTÜRK Derya , ALTINBİLEK Ertuğrul , COŞKUN Abuzer 
Published: April 2023

Aim: Early repolarization (ER) is a frequent indication, and it is important to correctly evaluate the effects of its benign and malignant forms in terms of prognosis. It was aimed to compare ER cases with the normal population in terms of multi-vessel disease, bypass and mortality.
Material and Method: This study comprised 776 patients aged 18 and older who admitted the emergency department between January 2015 and December 2020. 377 of these patients had ER in the electrocardiogram (ECG), 409 patients had normal ECGs and were added to the study as the control group. Age, gender, multi-vessel disease, by-pass and mortality relations of the patients were evaluated with angiographic findings.
Results: The mean age of 786 patients was 50.49±6.82 years, 372 (47.3%) were female, and the age range was 23-66 years (p
Carotid Doppler ultrasound measurements in allergic rhinitis patients
Authors: BEKİN SARIKAYA Pelin Zeynep , BAYAR MULUK Nuray , TAŞ Burak Mustafa , BASER Selcuk , ÇETİNKAYA Elif 
Published: April 2023

Aim: We aimed to determine with carotid Doppler ultrasound (CDU) whether the increase in inflammatory cells and mediators plays a role in intima-media thickening in patients with allergic rhinitis (AR) and to correlate this with the severity of the disease.
Material and Method: In this retrospective study, CDU reports and images of allergic rhinitis patients were evaluated in Group 1 (n=16). Score for allergic rhinitis (SFAR) and blood parameters that Hemoglobin (Hb), White Blood Cells (WBC), C-Reactive Protein (CRP), sedimentation levels were noted. Control group without AR consisted of 17 patients. In both groups, the presence of plaque on common carotid artery (CCA), and internal carotid artery (ICA) and all intima-media thickness were noted by CDU.
Results: In our study, CCA intima-media thickness and ICA intima-media thickness values of the AR group were significantly higher than those in the control group bilaterally (p
Distribution of ABO blood groups and Rh factor in benign and malign thyroid nodules
Authors: DENİZ Muzaffer Serdar 
Published: April 2023

Aim: Many factors affect the diagnostic value of the fine-needle aspiration biopsy applied for these thyroid nodules. I aimed to investigate whether one of these factors would be ABO blood groups and Rh factor and examine the relationship of these factors with the Bethesda categorization. Additionally, I aimed to evaluate ABO blood groups and Rh factors in patients with thyroid cancer.
Material and Method: This study was planned in a cross-sectional retrospective design. The data of the patients were obtained from the hospital data bank. In the analysis of 801 patients following the acceptance criteria, 412 patient data were obtained. Patients were divided into 4 (O, A, B, and AB groups) according to their blood groups and analyzed for nodules (solitary/ multinodular). Nodules were divided into malignant and benign, according to histopathological diagnosis, and all were analyzed.
Results: There was no difference in analyzing the demographic data according to the blood groups. The rates of the FNAB history were 51 (32.3%), 39 (24.2%), 14 (26.4%), and 13 (32.5%) in the same order of blood groups (p=0.393). In the analysis of the nodule type, multinodular did not differ from solitary nodules among the blood groups [O: 141 (89.2%); A:140(87%), B: 46(86.8%), and AB: 35(87.5%)]. Thyroid function status (euthyroid, hypothyroid, or hyperthyroid) was similar for all the blood groups (p=0.815). The O-group had 1 (0.6%) patient with Bethesda score-6, and the A-group had 2 (1.2%) patients with Bethesda score-6. For Bethesda score-5, per blood group had 2 patients. The histopathological distribution of malign nodules (p=0.782) is as follows: O-groups: 6 (33.3%) (Rh+:27%; Rh-:5,5%), A groups: 7(63,6%) (Rh+:54,5%; Rh-:0,9%), B groups: 2(20%)(Rh+:20%; Rh-:0%) and AB groups: 1(33%) (Rh+:33%) Rh-:0%).
Conclusion: Malign nodule rate was highest in the A-group and lowest in the B groups, although it did not differ in the overall analysis. No relationship was found between the Bethesda categorization of nodules, their sizes, type of nodules, type of thyroid cancer, and ABO blood groups.