bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efektivitas Backward Walking Program terhadap Perubahan Kontrol Postural dan Risiko Jatuh pada Lansia di Lembaga Kesejahteraan Sosial Batara Hati Mulia Kabupaten Gowa
Authors: Arsal Ulfah Widyastuti , Aras Djohan , Ariyandy Andi , Abdullah Meutiah Mutmainnah 
Published: August 2023

ABSTRACT The purpose of this study was to determine the effectiveness of the backward walking program (BWP) on changes in posture control and the risk of falls in the elderly. This study used a quasi-experimental design with a two-group pretest posttest control group design. Forty respondents were divided into two groups, 20 respondents belonged to the experimental group and 20 respondents belonged to the control group. The experimental group was given BWP treatment and the control group was given elderly gymnastics treatment. To measure postural control using a berg balance scale (BBS) and fall risk using a time up and go test (TUGT). Based on Wilcoxon's results, it was shown that there was an influence before and after BWP administration in the experimental group in BBS (p = 0.000) and TUGT (p = 0.000). Furthermore, from Mann Whitney, it is known that in BBS measurements, in the experimental group there was a significant difference with elderly gymnastics (p = 0.000), and in TUGT there was a very significant difference with elderly gymnastics (p = 0.000). The study concluded that BWP is more effective in improving postural control and fall risk in the elderly. And BWP is more effective than elderly gymnastics to improve postural control, and reduce the risk of falls in the elderly. Keywords: Backward Walking Program, Postural Control, Fall Risk ABSTRAK Tujuan dari penelitian ini adalah untuk mengetahui efektivitas backward walking program (BWP) terhadap perubahan kontrol postur dan risiko jatuh pada lansia. Penelitian ini menggunakan desain quasi experimental dengan desain two group pretest posttest control group design. Empat puluh responden dibagi menjadi dua kelompok, 20 responden termasuk dalam kelompok eksperimen dan 20 responden termasuk dalam kelompok kontrol. Kelompok eksperimen diberi perlakuan BWP dan kelompok kontrol diberi perlakuan senam lansia. Untuk mengukur kontrol postural menggunakan berg balance scale (BBS) dan risiko jatuh menggunakan time up and go test (TUGT). Berdasarkan hasil wilcoxon menunjukkan bahwa terdapat pengaruh sebelum dan sesudah pemberian BWP pada kelompok eksperimen dalam BBS (p=0,000) dan TUGT (p=0,000). Selanjutnya dari mann whitney diketahui bahwa pada pengukuran BBS, pada kelompok eksperimen ada perbedaan yang signifikan dengan senam lansia (p=0,000), dan pada TUGT terdapat perbedaan yang sangat bermakna dengan senam lansia (p=0,000). Penelitian ini menyimpulkan bahwa BWP lebih efektif dalam meningkatkan kontrol postural dan resiko jatuh pada lansia. Serta BWP lebih efektif dibandingkan senam lansia untuk meningkatkan kontrol postural, dan menurunkan risiko jatuh pada lansia. Kata Kunci: Backward Walking Program, Kontrol Postural, Resiko Jatuh
Tumor-Like Mass in Patient with Tuberculosis : Is It Really a Malignancy? a Case Report
Authors: Kurniawan Joshua , Ananda Annisa , Supriadi Kasum 
Published: August 2023

ABSTRACT Tuberculosis (TB) is not all about chronic cough or hemoptysis. The clinical manifestation of TB could be pulmonary and extrapulmonary, with the later defined as any site other than the lung, affected by the TB. The global burden for tuberculosis is still heavy, standing as the second leading infectious killer after COVID-19 (above HIV/AIDS), TB holds the 13th place of the leading cause of death. The World Health Organization (WHO) predicted around 1.6 million people died from TB, and 10.6 million people fell ill with TB worldwide in 2021. Due to the various manifestations and limitations of the diagnostic tools, determining the diagnosis and treatment of TB has always been a challenge since a long time ago. To give appropriate therapy, making an accurate diagnosis is crucial. It is known that extrapulmonary tuberculosis manifestation often mimics malignancy, both clinically and radiologically. The treatment for these cases should include treatment for the infection and the affected organ or site, following the recommended therapy dose and duration. Neurological examination should be evaluated, especially for tuberculosis of the spine. Surgical approach should be considered for cases with neurological deficits, patient with spine-at-risk, progressive spinal deformity, severe pain, spinal instability, or uncertain diagnosis. Physical therapy could be considered to improve respiratory function, improving muscle strength, reducing the pain, repair/improve the range of motion, sensory function, improve quality of life, and prevent other complications. Keywords: Extrapulmonary Manifestation, Mimics Malignancy, Tuberculosis
Faktor-Faktor yang Berhubungan dengan Kejadian Pre Eklamsi di Jawa Barat
Authors: Pratiwi Liliek , Fitriani Henny , Anggraini Dina Dewi 
Published: August 2023

ABSTRAK Di Indonesia pre eklamsi menjadi risiko yang paling membahayakan bagi ibu hamil. Pre eklamsi merupakan suatu kondisi akibat tekanan darah tinggi yang tidak terkontrol pada ibu hamil, jika kondisi pre eklamsi tidak dapat ditanganani, dapat berkembang menjadi eklamsi ataupun komplikasi kehamilan yang tentunya berdampak bagi ibu dan janin. Pre eklamsi sendiri di Jawa Barat memang sudah masuk dalam kegiatan Zero Mother Mortality Preeklmpsia (ZOOM) sejak Maret tahun 2017, di mana visinya menurunkan AKI serendah mungkin, dalam hal ini pre eklamsi menjadi sasaran utama karena factor risiko dapat dikenali dan dicegah, sarana prasarannya telah tersebar luas di Jawa Barat. Penelitian-penelitian dilakukan sebagai upaya terus menelaah factor risiko terbanyak penyebab pre eklamsi. Maka berdasarkan latarbelakang di atas, perlunya diteliti faktor-faktor yang berhubungan dengan kejadian pre eklamsi di Jawa Barat. Tujuan penelitian untuk mengetahui faktor-faktor yang berhubungan dengan kejadian pre eklamsi di Jawa Barat. Jenis penelitian menggunakan metode deskriptif korelasi onal dengan pendekatan cross sectional, yang menggunakan data sekunder. Dalam penelitian ini untuk mengetahui antara variabel independent (umur, paritas, pendidikan, pekerjaan, jarak kehamilan, riwayat hipertensi, usia kehamilan dan gemelli/kehamilan kembar). Dengan variabel dependen (pre eklamsi). Tujuan penelitian untuk mengetahui faktor-faktor yang berhubungan dengan kejadian pre eklamsi di Jawa Barat. Jumlah sampel dalam penelitian ini yaitu 140, dengan teknik simple random sampling. Ada hubungan umur dengan kejadian Pre eklamsi, tidak ada hubungan pendidikan dengan kejadian pre eklamsi, tidak ada hubungan pekerjaan dengan kejadian pre eklamsi, ada hubungan jarak kehamilan dengan kejadian pre eklamsi, tidak ada hubungan usia kehamilan dengan kejadian pre eklamsi, ada hubungan paritas kehamilan dengan kejadian Pre eklamsi, ada hubungan riwayat hipertensi dengan kejadian pre eklamsi, dan tidak ada hubungan gemelli atau kehamilan kembar dengan kejadian pre eklamsi. Jadi dengan melihat kesimpulan ini peran perawat dan tenaga kesehatan agar lebih rajin melakukan sistem pendekatan risiko dan peningkatan sistem rujukan yang cepat tanggap, sehingga cepat tertangani ibu hamil dengan kasus pre eklamsi. Kata Kunci : Faktor-Faktor yang Berhubungan, Pre-eklamsi, Jawa Barat
PENGEMBANGAN MEDIA FLASHCARD UNTUK MENINGKATKAN KETERAMPILAN MENULIS PUISI SISWA KELAS VII SMPN 10 SOKAN KALIMANTAN BARAT
Authors: Budan Budan , Rachman Anita Kurnia , Sumarti Endang 
Published: August 2023

Keterampilan menulis puisi adalah keterampilan sastra yang harus dicapai siswa dengan tekun berlatih sehingga dapat mengubah ide dan gagasannya menjadi karya puisi. Latar belakang penelitian ini adalah rendahnya keterampilan menulis puisi siswa Kelas Siswa VII SMPN 10 Sokan Kalimantan Barat. Penelitian ini bertujuan untuk mengembangkan, serta menguji kelayakan dan keefektifan media “Flashcard untuk Menulis Puisi”. Jenis penelitian adalah Penelitian dan Pengembangan dengan model ADDIE. Prosedur penelitian yaitu analyze, design, development, implementation dan evaluation. Subjek penelitian adalah 20 siswa kelas Siswa VII SMPN 10 Sokan Kalimantan Barat. Pengumpulan data menggunakan observasi, tes, wawancara, angket dan dokumen. Teknik analisis data menggunakan analisis data produk, analisis data awal, uji hipotesis, dan uji n-gain. Hasil penelitian menunjukkan media “Flashcard untuk Menulis Puisi ”sangat layak digunakan dengan presentase rata-rata penilaian ahli materi 86,63% dan ahli media 90,21%. Terdapat peningkatan rata-rata nilai siswa sebanyak 72%, hasil perhitungan N-Gain sebesar 0,559107 dengan kriteria sedang, dan hasil uji perbedaan rata-rata menunjukkan bahwa data sig (2-tailed) 0,000 < 0,05, sehingga disimpulkan bahwa rata-rata nilai antara pretest dan posttest mengalami perubahan signifikan. Simpulan penelitian: media “Flashcard untuk Menulis Puisi” layak dan efektif digunakan dalam kegiatan pembelajaran materi puisi oleh Siswa VII SMPN 10 Sokan Kalimantan Barat. Saran penelitian selanjutnya: lebih teliti dalam perencanaan pengembangan media flashcard, sebaiknya dikembangkan sesuai kebutuhan serta karakteristik siswa.
Pengembangan Media Pembelajaran Bahasa Inggris Interaktif Berbasis Android Untuk Kelas VIII di SMP PGRI 01 Gedangan
Authors: Krisdayanti Sinta Maya , Hadwijaya Munawwir 
Published: August 2023

Abstrak
Penelitian ini dibuat berdasarkan fenomena kurangnya media pembelajaran bahasa inggris yang menarik untuk digunakan di SMP PGRI 01 Gedangan. Berlatarbelakang akan hal ini, peneliti melakukan pengembangan media pembelajaran bahasa inggris interaktif berbasis android untuk kelas VIII di SMP PGRI 01 Gedangan. Penelitian ini bertujuan untuk mengembangkan media pembelajaran berbasis android yang dapat digunakan pada Smart phone siswa sekaligus meninjau tingkat kelayakannya sehingga dapat menghasilkan media pembelajaran yang efektif dan layak digunakan. Pengumpulan data dalam penelitian ini menggunakan wawancara, observasi dan angket-angket yang meliputi angket validasi ahli media, ahli materi dan respon peserta didik. Penelitian ini menggunakan metode penelitian dan pengembangan atau Research and Development (R&D). Prosedur pengembangan mengikuti prosedur Borg dan Gall yang disederhanakan ke dalam model pengembangan ADDIE yaitu analisis, Desain, Pengembangan, implementasi dan evaluasi. Hasil penilaian yang dilakukan menunjukkan bahwa media interaktif berbasis android ini mempunyai kelayakan yang sangat baik menurut ahli media dengan persentase 92,5%, ahli materi 80% dan respon peserta didik 89,80% yang berarti Media Pembelajaran ini “Sangat Layak” digunakan.
Pengaruh Metode Gambar dan Lagu Terhadap Peningkatan Kosakata Bahasa Inggris Anak Tk
Authors: Khoiriyah Asro'atul , Rahmah Tities Hijratur 
Published: August 2023

This study aims to determine the method of pictures and songs to increase the English vocabulary of kindergarten children. This research is an experimental research using Control Group Post-test Design. The population of this research is kindergarten children. The research sample was taken using a total sampling technique, all of the population was used as a sample. The research instrument is a test of the results of the English vocabulary of kindergarten children. Data analysis was taken from the results of the students' post-test. Furthermore, descriptive test, normality test, homogeneity test, and independent sample t test were carried out. The results showed that the average test value of the experimental class was greater than the average value of the control class. The independent test sample t test has a significance less than 0.05 so it can be concluded that there is a difference between the results of the English vocabulary of the experimental class and the control class, where the experimental class has a better score than the control class.
Keywords: Picture and song method, Vocabulary Improvement, English
ABSTRAKPenelitian ini bertujuan untuk mengetahui metode gambar dan lagu untuk meningkatkan kosakata bahasa Inggris anak TK. Metode penelitian yang digunakan adalah eksperimen dengan menggunakan Control Group Post-test Design. Populasi dalam penelitian ini adalah anak TK. Sampel penelitian diambil dengan teknik total sampling, seluruh populasi dijadikan sampel. Instrumen penelitian berupa tes hasil kosakata bahasa Inggris anak TK. Analisis data diambil dari hasil post-test siswa. Selanjutnya dilakukan uji deskriptif, uji normalitas, uji homogenitas, dan uji independent sample t test. Hasil penelitian menunjukkan bahwa rata-rata nilai tes kelas eksperimen lebih besar dari nilai rata-rata kelas kontrol. Uji independent sample t test memiliki signifikansi lebih kecil dari 0,05 sehingga dapat disimpulkan bahwa terdapat perbedaan hasil kosakata bahasa Inggris kelas eksperimen dan kelas kontrol, dimana kelas eksperimen memiliki skor yang lebih baik dari kelas kontrol.
Analysis of Risky Sexual Behaviors among Students
Authors: Asfia Fida , Ferial Linardita 
Published: August 2023

Sexual behavior has impacts on health, some of them are sexually transmitted diseases, such as HIV, the increasing rate of abortion among adolescents, and early-age pregnancies. The objective of this study was to determine the relationship between age, sex, exposure to pornography, knowledge, and attitude towards risky sexual behavior. This research was conducted to students at a private university in Banten. The samples of this study were 80 students selected by using simple random sampling method. The hypothesis testing was performed using the formula for testing the difference between two proportions. The research instrument was a questionnaire. The univariate and bivariate analysis was conducted by using chi-Square test. The research findings revealed that the majority of respondents engaged in risky sexual behavior (51.25%). There was a correlation between the variable of sex (pv= 0.001), exposure to pornography (pv = 0.000), and attitude (pv = 0.026) with risky sexual behavior. Respondents who were exposed to pornography had a 31-fold higher risk of engaging in risky sexual behavior compared to those who were not exposed to pornography. Additionally, respondents with a negative attitude had a 2-fold higher risk of engaging in risky sexual behavior compared to respondents with a positive attitude. On the other hand, the variable of age (pv = 0.949) and knowledge (pv = 0.814) were found to have no correlation with risky sexual behavior. Based on the aforementioned explanation, one approach to controlling risky sexual behavior was by promoting the development of a positive self-concept among adolescents.
Heterologous expression, purification and structural features of native Dictyostelium discoideum dye-decolorizing peroxidase bound to a natively incorporated heme
Authors: Kalkan Özlem , Kantamneni Sravya , Brings Lea , Han Huijong , Bean Richard , Mancuso Adrian P. , Koua Faisal H. M. 
Published: August 2023

The Dictyostelium discoideum dye-decolorizing peroxidase (DdDyP) is a newly discovered peroxidase, which belongs to a unique class of heme peroxidase family that lacks homology to the known members of plant peroxidase superfamily. DdDyP catalyzes the H2O2-dependent oxidation of a wide-spectrum of substrates ranging from polycyclic dyes to lignin biomass, holding promise for potential industrial and biotechnological applications. To study the molecular mechanism of DdDyP, highly pure and functional protein with a natively incorporated heme is required, however, obtaining a functional DyP-type peroxidase with a natively bound heme is challenging and often requires addition of expensive biosynthesis precursors. Alternatively, a heme in vitro reconstitution approach followed by a chromatographic purification step to remove the excess heme is often used. Here, we show that expressing the DdDyP peroxidase in ×2 YT enriched medium at low temperature (20°C), without adding heme supplement or biosynthetic precursors, allows for a correct native incorporation of heme into the apo-protein, giving rise to a stable protein with a strong Soret peak at 402 nm. Further, we crystallized and determined the native structure of DdDyP at a resolution of 1.95 Å, which verifies the correct heme binding and its geometry. The structural analysis also reveals a binding of two water molecules at the distal site of heme plane bridging the catalytic residues (Arg239 and Asp149) of the GXXDG motif to the heme-Fe(III) via hydrogen bonds. Our results provide new insights into the geometry of native DdDyP active site and its implication on DyP catalysis.
Intra-cervical lymphatic immunotherapy for dust mite-induced allergic rhinoconjunctivitis in children: a 3-year prospective randomized controlled trial
Authors: Wang Qixing , Wang Kai , Qin Yang , Huang Weijun , Li Yin , Yu Qingqing , Xiong Yu , Guo Yingwei , Zheng Rui , Tang Jun 
Published: August 2023

BackgroundPediatric allergic rhinoconjunctivitis has become a public concern with an increasing incidence year by year. Conventional subcutaneous immunotherapy (SCIT) has long treatment time, high cost and poor compliance. The novel immunotherapy significantly shortens the course of treatment by directly injecting allergens into cervical lymph nodes, which can perform faster clinical benefits to children.ObjectiveBy comparing with SCIT, this study aimed to evaluate the long-term efficacy and safety of intra-cervical lymphatic immunotherapy (ICLIT).MethodsThis is a prospective randomized controlled study. A total of 50 allergic rhinoconjunctivitis children with dust mite allergy was randomly divided into ICLIT group and SCIT group, receiving three cervical intralymphatic injections of dust mite allergen or three years of subcutaneous injection, separately. Primary outcomes included total nasal symptom scores (TNSS), total ocular symptom scores (TOSS), total symptom scores (TSS), total medication scores (TMS), and total quality of life score. Secondary outcomes included pain perception and adverse reactions during treatment. Other secondary outcome was change in Dermatophagoides pteronyssinus (Derp) and Dermatophagoides farina (Derf) -specific IgE level.ResultsBoth groups had significantly decreased TNSS, TOSS, TSS, TMS, and total quality of life score after 36 months of treatment (p&lt;0.0001). Compared with SCIT, ICLIT could rapidly improve allergic symptoms (p&lt;0.0001). The short-term efficacy was consistent between the two groups (p=0.07), while the long-term efficacy was better in SCIT group (p&lt;0.0001). The pain perception in ICLIT group was lower than that in SCIT group (p&lt;0.0001). ICLIT group was safer. Specifically, the children had only 3 mild local adverse reactions without systemic adverse reactions. The SCIT group had 14 systemic adverse reactions. At last, the serum Derp and Derf-specific IgE levels in ICLIT and SCIT groups decreased 3 years later (p&lt;0.0001).ConclusionICLIT could ameliorate significantly the allergic symptoms in pediatric patients with an advantage in effectiveness and safety, besides an improved life quality including shortened period of treatment, frequency of drug use and pain perception.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR1800017130.
Homologous versus Heterologous prime-boost COVID-19 Vaccination in autologous hematopoietic stem cell transplantation recipients: a blinded randomized controlled trial
Authors: Sharifi Aliabadi Leyla , Karami Manoochehr , Barkhordar Maryam , Hashemi Nazari Seyed Saeed , Kavousi Amir , Ahmadvand Mohammad , Vaezi Mohammad 
Published: August 2023

Background/PurposeOptimizing vaccine efficacy is of particular concern in patients undergoing hematopoietic stem cell transplantation (HSCT), which mainly have an inadequate immune response to primary SARS-CoV-2 vaccination. This investigation aimed to explore the potential prime-boost COVID-19 vaccination strategies following autologous (auto-) HSCT.MethodsIn a randomized clinical trial, patients who had already received two primary doses of receptor-binding domain (RBD) tetanus toxoid (TT) conjugated SARS-CoV-2 vaccine during three to nine months after auto-HSCT were randomized to receive either a homologous RBD-TT conjugated or heterologous inactivated booster dose four weeks after the primary vaccination course. The primary outcome was comparing the anti-S IgG Immune status ratio (ISR) four weeks after the heterologous versus homologous booster dose. The assessment of safety and reactogenicity adverse events was considered as the secondary outcome.ResultsSixty-one auto-HSCT recipients were recruited and randomly assigned to receive either homologous or heterologous booster doses four weeks after the primary vaccination course. The mean ISR was 3.40 (95% CI: 2.63- 4.16) before the booster dose with a 90.0% seropositive rate. The ISR raised to 5.12 (95% CI: 4.15- 6.08) with a 100% seropositive rate after heterologous (P= 0.0064) and to 3.42 (95% CI: 2.67- 4.17) with a 93.0% seropositivity after the homologous booster doses (P= 0.96). In addition, the heterologous group suffered more AEs following the booster dosage than the homologous group, but this difference was not statistically significant (p = 0.955). In multivariable analysis, the prime-boost vaccination strategy (heterologous versus homologous), the level of ISR before the booster dose, and the length of time between auto-HSCT and booster dose were the positive predictors of serologic response to a booster dose. No serious adverse event is attributed to booster vaccination.ConclusionIn patients who were primed with two SARS-CoV-2 vaccine doses during the first year after auto-HSCT, heterologous prime-boost COVID-19 vaccination with inactivated platform resulted in considerably enhanced serologic response and non-significantly higher reactogenicity adverse events than homologous RBD-TT conjugated prime-boost COVID-19 vaccination strategy.
Clinical application of a body area network-based smart bracelet for pre-hospital trauma care
Authors: Han Wei , Yuan Jin-Yang , Li Rui , Yang Le , Fang Jia-Qin , Fan Hao-Jun , Hou Shi-Ke 
Published: August 2023

ObjectiveThis study aims to explore the efficiency and effectiveness of a body area network-based smart bracelet for trauma care prior to hospitalization.MethodsTo test the efficacy of the bracelet, an observational cohort study was conducted on the clinical data of 140 trauma patients pre-admission to the hospital. This study was divided into an experimental group receiving smart bracelets and a control group receiving conventional treatment. Both groups were randomized using a random number table. The primary variables of this study were as follows: time to first administration of life-saving intervention, time to first administration of blood transfusion, time to first administration of hemostatic drugs, and mortality rates within 24 h and 28 days post-admission to the hospital. The secondary outcomes included the amount of time before trauma team activation and the overall length of patient stay in the emergency room.ResultsThe measurement results for both the emergency smart bracelet as well as traditional equipment showed high levels of consistency and accuracy. In terms of pre-hospital emergency life-saving intervention, there was no significant statistical difference in the mortality rates between both groups within 224 h post-admission to the hospital or after 28-days of treatment in the emergency department. Furthermore, the treatment efficiency for the group of patients wearing smart bracelets was significantly better than that of the control group with regard to both the primary and secondary outcomes of this study. These results indicate that this smart bracelet has the potential to improve the efficiency and effectiveness of trauma care and treatment.ConclusionA body area network-based smart bracelet combined with remote 5G technology can assist the administration of emergency care to trauma patients prior to hospital admission, shorten the timeframe in which life-saving interventions are initiated, and allow for a quick trauma team response as well as increased efficiency upon administration of emergency care.