bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complementors as ecosystem actors: a systematic review
Authors: Carst Alexandra Elena , Hu Yimei 
Published: August 2023

AbstractAs downstream actors providing innovations that enhance the value of the core proposition, complementors have been recognized as indispensable in many definitions of ecosystems. The increasing attention they have received in the past years demonstrates the concern to enrich our knowledge of complementors. With a hybrid approach of bibliometric and content analyses, this systematic literature review aims at a clearer understanding of complementors in an ecosystem setting. The findings confirm complementors’ strategic role in enhancing the ecosystem’s focal value proposition and impacting the ecosystem survival and success, more intensely since 2018. Several characteristics of complementors are also revealed. Despite autonomy being their most affirmed feature, an inconsistent understanding of complementors in different types of ecosystems is revealed. This study represents a pioneering attempt to systematically understand complementors as ecosystem actors through extant literature. Various research gaps in the extant ecosystem research were also identified, providing research directions in terms of complementors’ coopetitive interactions, strategies, and challenges in ecosystems.
A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer’s Disease Mouse Model
Authors: Naganuma Fumito , Murata Daiki , Inoue Marie , Maehori Yuri , Harada Ryuichi , Furumoto Shozo , Kudo Yukitsuka , Nakamura Tadaho , Okamura Nobuyuki 
Published: August 2023

Abstract
Purpose
Noninvasive imaging of protein aggregates in the brain is critical for the early diagnosis, disease monitoring, and evaluation of the effectiveness of novel therapies for Alzheimer’s disease (AD). Near-infrared fluorescence (NIRF) imaging with specific probes is a promising technique for the in vivo detection of protein deposits without radiation exposure. Comprehensive screening of fluorescent compounds identified a novel compound, THK-565, for the in vivo imaging of amyloid-β (Aβ) deposits in the mouse brain. This study assessed whether THK-565 could detect amyloid-β deposits in vivo in the AD mouse model.

Procedures
The fluorescent properties of THK-565 were evaluated in the presence and absence of Aβ fibrils. APP knock-in (APP-KI) mice were used as an animal model of AD. In vivo NIRF images were acquired after the intravenous administration of THK-565 and THK-265 in mice. The binding selectivity of THK-565 to Aβ was evaluated using brain slices obtained from these mouse models.

Results
The fluorescence intensity of the THK-565 solution substantially increased by mixing with Aβ fibrils. The maximum emission wavelength of the complex of THK-565 and Aβ fibrils was 704 nm, which was within the optical window range. THK-565 selectively bound to amyloid deposits in brain sections of APP-KI mice After the intravenous administration of THK-565, the fluorescence signal in the head of APP-KI mice was significantly higher than that of wild-type mice and higher than that after administration of THK-265. Ex vivo analysis confirmed that the THK-565 signal corresponded to Aβ immunostaining in the brain sections of these mice.

Conclusions
A novel NIRF probe, THK-565, enabled the in vivo detection of Aβ deposits in the brains of the AD mouse model, suggesting that NIRF imaging with THK-565 could non-invasively assess disease-specific pathology in AD.
Eco-friendly methodology for removing and recovering rare earth elements from saline industrial wastewater
Authors: Viana Thainara , Ferreira Nicole , Tavares Daniela S. , Abdolvaseei Azadeh , Pereira Eduarda , Henriques Bruno 
Published: August 2023

AbstractIn this study, response surface methodology (RSM) was applied with a Box–Behnken design to optimize the biosorption (removal and bioconcentration) of rare earth elements (REEs) (Y, La, Ce Eu, Gd, Tb) by living Ulva sp. from diluted industrial wastewaters (also containing Pt and the classic contaminants Hg, Pb, Zn, Cu, Co, and Cd). Element concentration (A: 10–190 μg/L), wastewater salinity (B: 15–35), and Ulva sp. dosage (C: 1.0–5.0 g/L) were the operating parameters chosen for optimization. Analysis of the Box–Behnken central point confirmed the reproducibility of the methodology and p-values below 0.0001 validated the developed mathematical models. The largest inter-element differences were observed at 24 h, with most REEs, Cu, Pb and Hg showing removals ≥ 50 %. The factor with the greatest impact (positive) on element removal was the initial seaweed dosage (ANOVA, p < 0.05). The optimal conditions for REEs removal were an initial REEs concentration of 10 μg/L, at a wastewater salinity of 15, and an Ulva sp. dosage of 5.0 g/L, attaining removals up to 88 % in 24 h. Extending the time to 96 h allowed seaweed dosage to be reduced to 4.2 g/L while achieving removals ≥ 90 %. The high concentrations in REE-enriched biomass (∑REEs of 3222 μg/g), which are up to 3000 times higher than those originally found in water and exceed those in common ores, support their use as an alternative source of these critical raw materials.
Sustainable synthesis of multifunctional nanomaterials from rice wastes: a comprehensive review
Authors: Chakroborty Subhendu , Pal Kaushik , Nath Nibedita , Singh Varun , Barik Arundhati , Soren Siba , Panda Pravati , Asthana Nidhi , Kyzas George Z. 
Published: August 2023

AbstractMore than 60% of India’s population relies on agriculture as their primary source of income, making it the nation’s most important economic sector. Rice husk (often abbreviated as RH) is one of the most typical by-products of agricultural production. Every five tonnes of rice that is harvested results in the production of one tonne of husk. The concept of recycling and reusing waste from agricultural production has received interest from a variety of environmental and industrial perspectives. A wide variety of nanomaterials, including nano-zeolite, nanocarbon, and nano-silica, have been discovered in agro-waste. From rice cultivation to the finished product, there was a by-product consisting of husk that comprised 20% of the overall weight, or RH. The percentage of silica in RH ash ranges from 60 to 40%, with the remaining percentage consisting of various minerals. As a direct consequence of this, several distinct approaches to generating and extracting nanomaterial from rice husk have been developed. Because it contains a significant amount of cellulose and lignin, RH is an excellent and economical source of carbon precursor. The goal of this chapter is to produce carbon-based nanomaterials from RH.
Robinobiosylation of tyrosol by seed meal from Rhamnus cathartica
Authors: Haluz Peter , Mastihubová Mária , Karnišová Potocká Elena , Pančík Filip , Mastihuba Vladimír 
Published: August 2023

AbstractTyrosol robinobioside was prepared under catalysis of robinobiosidase-containing seed meal from common buckthorn Rhamnus cathartica. Robinin, a flavonoid isolated from the flowers of black locust (Robinia pseudoacacia) served as a robinobiosyl donor. The glycosylation proceeded predominantly on the primary hydroxyl of tyrosol, typically yielding mixtures of isomeric glycosides in ratios of 5:1 to 8:1 with overall yields of robinobiosides higher than 20%. This is the first robinobiosylation promoted under enzymatic catalysis.
Insights into the fauna associated with Egeria densa at the upper section of the international Minho River estuary (NW Iberian Peninsula) 3 decades after its establishment
Authors: Gomes Nuno , de Araújo Costa Dimítri , Martins Duarte , Rocha Sónia , Sousa-Pinto Isabel , Antunes Carlos 
Published: August 2023

AbstractThe macrophyte Egeria densa Planchon, 1849 is a freshwater plant native to the subtropical regions of South America. Fast vegetative reproduction and efficient dispersal allow this species to form extensive beds that produce high levels of oxygen in freshwater ecosystems, generating microhabitats that act as refuge and nursery for an array of organisms, increasing sedimentation and light availability. Despite its undisputable ecological role, it is considered invasive and is present on all continents except Antarctica with the first records in Europe occurring at the 20th century. At the international Minho River (NW Iberian Peninsula), the observation of its presence was noted in the 1990s and is now an established population in this ecosystem. This study is the first descriptive-taxonomical assessment of the associated fauna with the exotic macrophyte E. densa, using both morphological and molecular approaches, three decades after its establishment in the international Minho River. Results indicate the presence of a faunal assemblage, composed a total of 20 identified species, including platyhelminths, hydrozoans, bryozoans, molluscs (Gastropoda), annelids (Oligochaeta and Hirudinea), crustaceans (Ostracoda, Copepoda, Branchiopoda and Amphipoda), aquatic mites and insects. Paludicella aff. articulata (Ehrenberg, 1831), Girardia sinensis Chen & Wang, 2015, Lebertia insignis Neuman, 1880 and Ceriodaphnia rigaudi Richard 1894 are recorded for the first time in Portugal.
Gabapentinoid detection in coronial casework in Gold Coast, Australia: a 5-year retrospective study
Authors: Thompson Isabella , Gadsby Zeena , Martin Jeremy , Thompson Melissa , Tse Rexson 
Published: August 2023

AbstractGabapentinoids is a class of drug with analgesic, anxiolytic, and anticonvulsant properties and has a reported increase in prescription, use, and adverse outcomes. Regional studies are scant, and postmortem toxicological data may characterise patterns of regional use and inform local interventions. Characterising drug and non-drug-related deaths with gabapentinoid detection may also aid in toxicology interpretation. A 5-year retrospective study on all deaths admitted to the Gold Coast University Hospital under where toxicological analysis was performed. Of the gabapentinoids, only pregabalin was detected over the study period, and annual rates of detection did not differ significantly over the period (7.4–12.4%). In cases where pregabalin was detected, it was 15 times more likely to be a drug-related death. Drug-related deaths where pregabalin was detected have higher levels of pregabalin, are younger, and had a greater proportion of concurrent opioid detection. Postmortem detection of pregabalin was associated with drug-related deaths. Higher levels, younger decedents, and concurrent use of opioids were found in drug-related deaths. Public health interventions and regulated prescribing to target concurrent pregabalin and opioid use may address the burden of pregabalin drug-related deaths.
Interface catalytic reduction of alumina by nickle for the aluminum nanowire growth: Dynamics observed by in situ TEM
Authors: Wang Zichun , Wang Dan , Li Ang , Wang Lizhuo , Han Xiaodong , Jiang Yijiao , Chen Jianfeng , Huang Jun 
Published: August 2023

AbstractMetal nanowires show promise in a broad range of applications and can be fabricated via a number of methods, such as vapor–liquid–solid process and template-based electrodeposition. However, the synthesis of Al nanowires (NWs) is still challenging from the stable alumina substrate. In this work, the Ni-catalyzed fabrication of Al NWs has been realized using various Al2O3 substrates. The growth dynamics of Al NWs on Ni/Al2O3 was studied using in situ transmission electron microscopy (TEM). The effect of alumina structures, compositions, and growth temperature were investigated. The growth of Al NWs correlates with the Na addition to the alumina support. Since no eutectic mixture of nickel aluminide was formed, a mechanism of Ni-catalyzed reduction of Al2O3 for Al NWs growth has been proposed instead of the vapor–liquid–solid mechanism. The key insights reported here are not restricted to Ni-catalyzed Al NWs growth but can be extended to understanding the dynamic change and catalytic performance of Ni/Al2O3 under working conditions.
Critical minerals versus major minerals: a comparative study of exploration budgets
Authors: Castillo Emilio , del Real Irene , Roa Cintia 
Published: August 2023

AbstractDisruptions in the minerals supply chain play a central role in defining the future stock of minerals; therefore, an in-depth analysis of the outcomes and variables affecting exploration is required. In comparative terms, the exploration of critical minerals and major minerals presents geological and technical differences; thus, exploration budgets for critical minerals should be expected to depart from those observed in other minerals. In this context, the main goal of this paper is to contrast how exploration budgets differ between critical and major minerals when considering a set of key variables. We take a multivariate statistical analysis approach based on firm-level budget exploration data to show four key findings: exploration budgets allocated for critical minerals remain consistently lower than major minerals even when controlling for other factors. Moreover, they present a higher sensitivity to fluctuations in commodity prices. Besides, the investment made by larger companies in critical minerals significantly lags behind those made by junior companies. Additionally, the focus of exploration activity for critical minerals predominantly lies in the earlier stages of the exploration process. We expect these initial results to be used as a step forward to facilitate the discussion about exploration policies and, consequently, the reliability of the supply chain.
Synthesis of a novel chloroquinoline, rhodanine encompassed 1,2,3-triazole scaffolds and molecular docking evaluation of their cytotoxicity
Authors: Suryanarayana Kotyada , Gangu Kranthi Kumar , Kerru Nagaraju , Khatana Kavita , Satyanarayana Botcha , Maddila Suresh 
Published: August 2023

AbstractA novel series of quinoline-linked rhodanine bearing 1,2,3-triazole analogs (10a-l) have been designed and prepared. All the novel hybrids were analyzed and characterized by spectroscopic performances like 1H-NMR, 13C-NMR, and HR-MS analysis. The anticancer efficiency of final molecules was screened for their in vitro activity against the diverse cancer cells lines like HeLa (cervical carcinoma), MCF-7 (human breast), HT-29 (colon cancer), and Caco-2 (human epithelial). Amongst, compound (10c) exhibited more potent anticancer activity than Combretastatin-A4 as a standard drug against MCF7, Caco-2, HeLa, HT-29, and Caco-2 cancer cells with IC50 values of 3.67, 3.93, 4.92, and 6.83 μM, respectively. The overview of an electron-releasing substituent on the aryl ring exhibited potent anticancer activity. It is the first report to reveal the quinoline-linked rhodanine-bearing 1,2,3-triazole scaffolds as potential antitumor agents with inclusive docking analysis.
Graphical abstract
The Two Fundamental Problems of Epistemology, Their Resolution, and Relevance for Life Science
Authors: Smit Harry 
Published: August 2023

AbstractAmong the many fundamental problems Wittgenstein discussed, two are especially relevant for evolutionary theory. The first one is the problem of negation and its relation to the intentionality of thought. Its resolution answers the question of how thought can anticipate reality though what is thought may not exist, and explains how empirical propositions are distinguishable from mathematical, logical, and conceptual (or what are traditionally called metaphysical) propositions. The second is the problem of the grounds of sensory experience. Wittgenstein’s resolution of this problem is revolutionary since he showed that first-person, present-tense expressions (these are sentences by which we express what goes on in our mind) have no grounds at all, clarifying why we should abandon (all variants of) representative idealism. In combination with the resolution of the first problem, it enables us to develop new explanations about how during the course of development and evolution the mind evolves and evolved.
Reduction of PSII photosynthetic performance by low temperature is the reason for the growing inhibition of Kobresia pygmaea Clarke
Authors: Shi Shengbo , Shi Rui , Zhou Dangwei , Li Tiancai , De Kejia , Gao Xiuzhen , Ma Jialin , Wang Fanglin 
Published: August 2023

AbstractKobresia pygmaea Clarke is mainly distributed in the alpine region from 3800 to 4500 m elevation on the Qinghai-Tibet Plateau. It is excellent in low-temperature tolerance and trampling resistance and plays an important role in maintaining the stability of regional ecological environments. Mainly based on the chlorophyll fluorescence imaging technique, using grass sods blocks with a size of 20 × 20 cm2 collected from K. pygmaea forb meadow, simulated a low-temperature treatment in cultural room with 8 °C/4 °C (day/night) at diurnal photoperiod, we analyzed the effects of low temperature on PSII photochemical efficiency and non-photochemical quenching, as well as the interaction between low temperature and light intensity. The results showed that low temperature could significantly decrease the maximum quantum efficiency of PSII photochemistry (Fv/Fm) and inhibit the leaf growth of K. pygmaea. The light response curve of PSII relative linear electron transport rate was reduced by low temperature, while it recovered to almost normal level after two days of removing adversity. Further experiments under steady-state actinic light confirmed that light intensity was the main factor affecting the PSII photochemical efficiency, and its reduction caused by the low temperature showed a certain degree of reversibility. The non-photochemical quenching (NPQ) was significantly affected by light intensity, and its fast and slow components (NPQf and NPQs) in NPQ accounted for 36% and 64% of NPQ, respectively. The decrease in NPQf and corresponding increase in NPQs slowly recovered after relieving from low-temperature condition. The relative inhibition of photosynthesis (Pinh) was significantly enhanced by low temperature and reduced after removal of adversity. Strong light intensity could intensify the adverse effect of low temperature on PSII operating efficiency Fq′/Fm′ and efficiency factor Fq′/Fv′, as well as NPQ. In conclusion, low temperature was one of the main reasons limiting the photosynthetic performance of K. pygmaea on the Qinghai-Tibet Plateau and could aggravate photosynthetic photoinhibition. The adversity of low temperature frequently occurring in the plant growing season on the Qinghai-Tibet Plateau was constituted of the main factor of the low productivity level in alpine meadow.
Diabetic striatopathy: an updated overview of current knowledge and future perspectives
Authors: Arecco A. , Ottaviani S. , Boschetti M. , Renzetti P. , Marinelli L. 
Published: August 2023

Abstract
Purpose
Diabetic striatopathy (DS) is a rare complication of poorly controlled diabetes mellitus (DM), characterized by hyperglycemia associated with chorea/ballism and characteristic reversible basal ganglia abnormalities on computed tomography (CT) and/or magnetic resonance imaging (MRI). We propose a narrative review of the literature on this topic, currently unknown to most, and about which physicians should be aware. We intend to summarize, critically review, and take to mean the evidence on this disorder, describing its typical features.

Methods
We searched Pubmed for English-language sources using the following keywords in the title and the abstract: diabetic striatopathy, hyperglycemic non-ketotic hemichorea/hemiballism, chorea/hemichorea associated with non-ketotic hyperglycemia, diabetic hemiballism/hemichorea, chorea, hyperglycemia, and basal ganglia syndrome. We collected scientific articles, including case reports, reviews, systematic reviews, and meta-analyses from the years 1975 to 2023. We eliminated duplicate, non-English language or non-related articles.

Results
Older Asian women are more frequently affected. Suddenly or insidiously hemichorea/hemiballism, mainly in the limbs, and high blood glucose with elevated HbA1c in the absence of ketone bodies have been observed. Furthermore, CT striatal hyperdensity and T1-weighted MRI hyperintensity have been observed. DS is often a treatable disease following proper hydration and insulin administration. Histopathological findings are variable, and no comprehensive hypothesis explains the atypical cases reported.

Conclusion
DS is a rare neurological manifestation of DM. If adequately treated, although treatment guidelines are lacking, the prognosis is good and life-threatening complications may occur occasionally. During chorea/hemiballism, we recommend blood glucose and HbA1c evaluation. Further studies are needed to understand the pathogenesis.
Phenology as a tool to gain more insights into the grass pollen season
Authors: Bastl Katharina , Bastl Maximilian , Berger Markus , Dirr Lukas , Berger Uwe E. 
Published: August 2023

Abstract
Background
Grass pollen allergy is the most common pollen allergy in the world. The grass family (Poaceae) consists of many genera and species of allergenic importance, but all share a uniform pollen grain morphology. Phenology is the key to discriminate different taxa.

Methodology
PubMed was used as the search engine. The publications found were selected based on their relevance and summarized.

Results
Studies with this focus are still rare. The composition of grass genera and species varies largely from region to region. Some taxa play a more important role in terms of pollen release and allergenicity than others.

Conclusion
Phenological routines need deep botanical knowledge and are time-consuming. Nonetheless, they should be integrated into studies on the grass pollen season since they allow a more precise understanding.
An efficient long-text semantic retrieval approach via utilizing presentation learning on short-text
Authors: Wang Junmei , Huang Jimmy X. , Sheng Jinhua 
Published: August 2023

AbstractAlthough the short-text retrieval model by BERT achieves significant performance improvement, research on the efficiency and performance of long-text retrieval still faces challenges. Therefore, this study proposes an efficient long-text retrieval model based on BERT (called LTR-BERT). This model achieves speed improvement while retaining most of the long-text retrieval performance. In particular, The LTR-BERT model is trained by using the relevance between short texts. Then, the long text is segmented and stored off-line. In the retrieval stage, only the coding of the query and the matching scores are calculated, which speeds up the retrieval. Moreover, a query expansion strategy is designed to enhance the representation of the original query and reserve the encoding region for the query. It is beneficial for learning missing information in the representation stage. The interaction mechanism without training parameters takes into account the local semantic details and the whole relevance to ensure the accuracy of retrieval and further shorten the response time. Experiments are carried out on MS MARCO Document Ranking dataset, which is specially designed for long-text retrieval. Compared with the interaction-focused semantic matching method by BERT-CLS, the MRR@10 values of the proposed LTR-BERT method are increased by 2.74%. Moreover, the number of documents processed per millisecond increased by 333 times.