bluuebunny/crossref_metadata_2025_split huggingface dataset:
Joint modeling of longitudinal measures of pneumonia and time to convalescence among pneumonia patients: a comparison of separate and joint models
Authors: Azmeraw Sindu , Wube Yenefenta , Lakew Demeke 
Published: December 2022

Abstract
Background
Globally, pneumonia is the leading cause of children under age five morbidity and mortality with 98% of deaths in developing countries.

Objective
This study aimed to identify the determinants of longitudinal measures of pneumonia and time to convalescence or recovery of under five admitted pneumonia patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia.

Methods
A prospective cohort study was conducted among a randomly selected sample of 101 pneumonia patients using simple random sampling who were on follow up from December 2019 to February 2020. A Linear mixed effect model were used for the longitudinal outcomes and joint model for modeling both longitudinal and time to event outcomes jointly respectively.

Results
The significant values of shared parameters in the survival sub model shows that the use of joint modeling of multivariate longitudinal outcomes with the time to event outcome is the best model compared to separate models. The estimated values of the association parameters: − 0.297(p-value = 0.0021), − 0.121) (p-value = < 0.001) and 0.5452 (p-value = 0.006) indicates association of respiratory rate, pulse rate and oxygen saturation respectively with time to recovery. The significant values show that there is an evidence to say that there is a negative relationship between longitudinal measures of respiratory rate and pulse rate with time to recovery and there is positive relationship between longitudinal measures of oxygen saturation with time to recovery.
Variables age, birth order, dangerous signs, severity and visit time were significant factors on the longitudinal measure of pulse rate. The significant factors related to longitudinal measures of oxygen saturation were birth order, severity and visit. From this we can conclude that birth order, severity and visit were significant variables that simultaneously affect the longitudinal measures of respiratory rate, pulse rate and oxygen saturation of patients at 5% level of significance.

Conclusion
Results of multivariate joint analysis shows that severity was significant variable that jointly affects the three longitudinal measures and time to recovery of pneumonia patients and we can conclude that patients with severe pneumonia have high values of respiratory rate and pulse rate as well as less amount of oxygen saturation and they need longer time to recover from the disease.
A cost-effective method for detecting mutations in the human FAM111B gene associated with POIKTMP syndrome
Authors: Arowolo Afolake , Rhoda Cenza , Mbele Mzwandile , Oluwole Oluwafemi G. , Khumalo Nonhlanhla 
Published: December 2022

Abstract
Background
Mutations of the human FAM111B gene are associated with hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis (POIKTMP), a rare and autosomal dominant multi-systemic fibrosing disease. To date, a total of 36 cases are documented, with eleven associated mutations identified and confirmed by Whole-Exome Sequencing and Sanger sequencing. However, these methods require a certain level of expertise. The FAM111B gene was annotated using the SNAPGENE tool to identify various restriction enzymes. The enzymes that cut at the positions where mutations of interest have been reported were selected. The method was implemented using the DNA samples extracted from the skin fibroblast collected from an affected South African family and unrelated control.

Results
The findings showed that of the eleven FAM111B mutational sites investigated with this method, ten mutations can be identified including the known mutation FAM111B NM_198947.4: c.1861T>G (pTyr621Asp) associated with the POIKTMP in South Africa.

Conclusions
Limited access to molecular diagnosis contributes to why POIKTMP is rarely diagnosed. Our study describes an inexpensive PCR–RFLP method to screen for POIKTMP FAM111B gene mutations. The PCR–RFLP can be used as a cost-effective method for diagnosing FAM111B mutations in POIKTMP, and it does not require having robust experience in molecular biology.
A multidisciplinary transitional pain service to improve pain outcomes following trauma surgery: a preliminary report
Authors: Flynn Hannah K. , Manoharan Divya , Hsu Yea-Jen , Xie Anping , Shechter Ronen , Hanna Marie , Speed Traci J. 
Published: December 2022

Abstract

Objectives
Trauma (i.e., musculoskeletal injury from a blunt or penetrating force) can change the trajectory of a person’s life. Patients often experience chronic pain, reduced quality of life, long-term opioid therapy, and psychiatric comorbidities after trauma surgery. This case report presents clinical outcomes of four patients who received postsurgical pain care in a transitional pain service (TPS) that provides long-term coordinated multimodal pain care, opioid tapering plans, and psychiatric care.

Methods
The Personalized Pain Program (PPP) measures prescription opioid use and patient-reported outcomes: pain severity and pain interference (Brief Pain Inventory), pain catastrophizing (Pain Catastrophizing Scale), insomnia severity (Insomnia Severity Index), physical and mental health functioning (SF-12 pre-COVID-19; SF-36 during COVID-19 pandemic) at initial and subsequent clinic visits.

Results
All four patients reduced their postsurgical opioid use with concurrent reductions in pain and improved functioning while receiving postoperative care in the PPP (average length of treatment: 2.8 years). Psychiatric co-treatment addressed the onset or exacerbation of mental health comorbidities following trauma.

Conclusions
Long-term multidisciplinary pain care may improve post-trauma recovery and reduce risks of long-term opioid therapy and disability. Prospective studies are needed to evaluate the effectiveness of TPSs for patients undergoing trauma surgery.
SINKRETISME AGAMA DAN BUDAYA: Tradisi Sumpah Menggunakan Al-Quran Khatam Rayab
Authors: Yansah Savri 
Published: December 2022

This research is motivated by the problems raised in Religious and Cultural Syncretism: The Tradition of the Oath Using the Al-Quran Khatam Rayab. Khatam Rayab is an ancient Koran found in Karang Baru Village, Padang Ulak Tanding District, which is used to solve problems that cannot be resolved amicably and legally. The purpose of this study was to determine the process of implementing the oath using the Koran Khatam Rayab. This research is a field research that uses qualitative descriptive methods, taking research topics or respondents using ethnographic methods. Ethnography is an approach used to understand how people in a community interact and are observed in everyday life. Ethnography is used to examine human behavior related to the development of communication technology in certain social and cultural settings. In this study, the researchers used an approach of observation, interviews, documentation, and data analysis techniques, namely data reduction, data presentation and conclusion drawing, which became the research of the owner of Khatam Rayab Mr. Hur, Joko's heir, people who had promised and the community. Based on the research results of Religious and Cultural Syncretism: Tradition of Oaths Using the Khatam Rayab Al-Quran, namely at the stage before the implementation of the oath, offerings and dowries are in the form of cash. The da'wah values contained in the tradition are: life values, discipline values, social values, cultural values and honesty values. Berdasarkan hasil penelitian Sinkretisme Agama dan Budaya: Tradisi Sumpah Menggunakan Al-Quran Khatam Rayab yaitu pada tahapan proses sebelum melaksanakan sumpah harus menggunakan sesaji dan mahar berupa uang tunai. Nilai-nilai dakwah yang terdapat dalam tradisi tersebut yaitu: nilai keimanan, nilai kedisiplinan, nilai sosial, nilai budaya dan nilai kejujuran.
Lighting, housing and health: contributions of the 2030 Agenda for sustainable cities and communities
Authors: Mendes Élgen Soares , Toledo Renata Ferraz de 
Published: December 2022

As an important factor in the promotion of environmental comfort, lighting in houses has been increasingly analyzed in studies about health and well-being. Understanding how human exposure to light (artificial or natural) can influence health and the possible beneficial or harmful aspects can contribute to developing strategies that optimize its use and effects, both on human health and on sustainability. Thus, the objectives of this research were to analyze if, and how, lighting in houses can influence human health and determine if the lighting, housing and health topics are connected to the 2030 Agenda Sustainable Development Goals (SDGs). This is a bibliographic review carried out through searches in the Scientific Electronic Library online and EBSCO Information Services databases, based on the following descriptors: lighting, health, housing, environmental comfort and sustainable development, some of their synonyms and in different combinations, researched in Portuguese and English. Other criteria were also used to select the publications to be analyzed, which, in turn, gave rise to two thematic groups: the first addressing environmental comfort in housing, analyzing its relationship with the residents' health and listing important elements for the promotion of environmental comfort; and the second devoted to specifically analyzing the relationship between lighting and human health. When analyzed in an interdisciplinary and intersectoral way, we understand that the “lighting-housing-health” relationship can be connected to the SDGs and effectively contribute to the 2030 Agenda.
The effects of “new centralities” on Goiania’s urban space
Authors: Duarte Jhonier Silva Santos , Mahler Christine Ramos , Rezende Wagner de Souza 
Published: December 2022

This article describes the process of configuration of new centralities in the city of Goiânia and its effects on urban space production, mainly in the last 50 years. Initially, the concepts of center and centrality are presented, followed by the analysis of three fundamental conditions of urban structuring in the metropolis: “unplanned” urban expansion; multiple urban development axes; and (apparently) disconnected and fragmented centralities. Subsequently, the production of urban space in Goiânia (1933-2020), is the object of analysis, as well as the effects of the “new centralities” in its urban expansion process. The urban analysis methodology consists of the analysis of historic documentation from its urban planning process through the last decades and fieldwork documentation. Thus, this article discusses the (re)configuration and (re)signification of centralities as a result of the social production of urban space, as well as its effects on urban expansion and on the expansion of socio-spatial segregation in Goiânia in the 21st century. Therefore, we focus in the description of the strategies of economic and political control of the territory in the emergence of “new centralities”, understanding it as protagonists of the urban structuring of the metropolis of Goiás, influencing urban expansion, socio-spatial segregation and institutionalization of the urban peripheries.
MANAGEMENT OF CORN CICADA WITH BIOINSUMOS A BASE OF FUNGUS (BEAUVERIA BASSIANA)
Authors: Brasil  , Vanessa SAUER Aline , L. CANCELLIER Eduardo , Diego Peña Gonzalo 
Published: December 2022

Bioinsumos are governed by Federal Decree no. 10. 375 of May 26, 2020, which uses in its attributions, bioinsumption is considered the product, process or technology of plant, animal or microbial origin, intended for use in the production, storage and processing of agricultural products, in aquatic production systems or planted forests, which positively interfere in the growth, development and response mechanism of animals, plants, microorganisms and derived substances and that interact with products and physicochemical and biological processes. The bioinputs compatibility test was performed using the fungus Beauveria bassiana (Bals.) Vuill., strain PL63 (minimum of 1 x 108 viable conidia/ge and Isaria fumosorosea CEPA ESALQ-1296 (min. of 2.5 x 109 viable conidia/mL) at a dose of (500 gr/ha) associated with the insecticide based on Bifenthrin + Carbosulfan (600 mL/ha). In the field, the experiment was conducted in Sitio Santa Maria in the Municipality of Bandeirantes-PR located between the coordinates 50º37'63" WO and 23º15'79" S. Data collection was performed over a period of 4 months, with 1 crop in the management of corn culture. Soil analysis was performed (0 to 20 cm depth). The work for the evaluation of the fungus and insecticide, being carried out in the field, when the plants presented in the phase V2, V4, V6. The evaluations took place at 3, 7, 10, 14 days, after each application, total area considered (m2). The experimental design used was randomized blocks with 4 repetitions, with 15.75 m² plots (2.25 x 7) and spacing of 45 centimeters between rows, constituting 6 treatments, totaling 24 plots.
POLITICAL IDEOLOGY OF SIBERIAN DEMOCRATIC REGIONALISM (OBLASTNICHESTVO) IN THE INTERPRETATIONS OF MODERN FOREIGN RESEARCHERS
Authors: Golovinov Aleksandr V. 
Published: December 2022

Aim. To identify and show interpretive assessments of the political ideology of Siberian democratic regionalism in the latest foreign studies.Methodology.The current study is based on historiographical methodology. The main instrument of the study is political and textual analysis of foreign researches by British, American, European and non-Western authors.Results.The author establishes the contours of the modern Anglo-American, European and non-Western narrative in understanding the ideology of Siberian regionalism (regionalism).Research implications.The work has both scientific and academic and practical significance. In terms of research, this study sheds light on the interpretation of the essence and content of the political ideology of Siberian democratic regionalism. We believe these results can be useful for a wide range of researchers involved in the problems of Russian political thought. From the practical point of view, this work can be used in the development of state programs and strategies of counteracting the cultivation of secession-oriented ideas by the unfriendly West. The results of the work done may be implemented in the regional and national policy of modern Russia in order to preserve the internal political stability and territorial integrity of the country.
Intraoperative cardiac arrest in the prone position in neurosurgery: A reel challenge for the anesthesiologist
Authors: Ilyass Masad , Khalil Abouelalaa , Abdelahamid Jaafari , Mohamed Mezyane , Naoufal Doghmi , Abderrahmane Elwali , Abdelouahed Baite , Mustapha Bensghir 
Published: December 2022

The Cardiac Arrest in Elective Neurosurgery, is complex and different from other types, as it’s influenced by the patient’s position, the surgical procedure, and the equipment used to fix the skull;
we report a case of a patient admitted for lumbar spine surgery in prone position who presented an intraoperative cardiac arrest.
chest compressions can be started immediately for prone patients; some studies confirmed the efficacy of back compressions but patients should be turned supine if possible.
When defibrillation were necessary in patients ventilated in the prone position, defibrillation should be attempted, as placing the patient in the supine position would take precious minutes and would reduce the chances of successful defibrillation.
Evidence is rare when dealing with neurosurgical patients, and more efforts are needed in understanding the etiologies, mechanisms and the specificities of its management.
The use of theoretical frameworks by Master of Public Administration (MPA) graduates at a selected South African university of technology
Authors: Hendrickse Rozenda 
Published: December 2022

Scholars contend that public administration, as a discipline, is still in its infancy and, more often than not, fumbles for its own identity. It is generally regarded as an amalgamation of various disciplines. It is therefore no wonder that scholars in public administration, more often than not, fail to locate their empirical research, in sound theoretical frameworks for research in public administration, in general. The core objective of the study was to determine whether Master of Public Administration (MPA) graduates, from a selected university of technology in South Africa, grounded their research in theoretical frameworks, rooted in the identified public administration domains. Desktop research was employed where purposely selected MPA dissertations were scrutinised, using content analysis. MPA qualifications generally comprise a range of modules in conjunction with the production of a mini-thesis. This has not been the case at the Cape Peninsula University of Technology (CPUT) since 2016. MPA graduates are required to produce a full dissertation only. The study intended to highlight the importance of conducting research that contributes to public administration theory development, especially at universities of technology. The study found that if CPUT wants to acquire a competitive edge in the international higher education landscape in general and in the field of public administration in particular, it must aspire to deliver MPA graduates who demonstrate the ability to grow the mass of theoretical knowledge in the discipline. The study recommends that theoretical frameworks, in the study domains associated with research in public administration be taught explicitly in the form of seminars in the absence of teaching them in formal credit-bearing modules, which is the case at CPUT.
The accuracy of the crime of genocide in the bill of kuhp 2019 according to human rights regulations
Authors: Inez Devina Clarissa  , Tomy Michael  
Published: December 2022

With regulations regarding human rights that have been regulated, norms and institutions should be able to protect humans and their rights to life so that they do not live under threat. Mainly, because the crime of genocide has been regulated by various international human rights instruments like the International Criminal Tribunal for Rwanda (ICTR), the 1948 Genocide Convention, and to 1988 Rome Statute on International Criminal Court. But facts show that cases regarding the crime of genocide are still happening. The Criminal Code as a law adopted from the Dutch-herited Criminal Code requires an appropriate codification between the awareness and legal needs of the Indonesian nation, thus requiring a new criminal arrangement to replace the old regulation. The 2019 RKUHP then emerged as a solution, but there are still many ambiguous article formulations that make the 2019 RKUHP still have to be reviewed. An example is the article regarding the crime of genocide in Article 598 of the 2019 RKUHP. Some of the weaknesses of the article are in things such as the fall of authority over the implementation of a crime and one of its regulations that the convict gets a pardon or amnesty written in Article 140. If the crime of genocide remains in the 2019 RKUHP, then a number of revisions must be made by reviewing the Rome Statute so that there is no expansion of the meaning in the article regarding the crime of genocide.
The phenomenon of financial distress of manufacturing companies in Indonesia during the Covid-19 Pandemic
Authors: Handayati Puji , Izzalqurny Tomy Rizky , Fauzan Slamet , Shobah Nurus 
Published: December 2022

The purpose of this study is to examine the differences in the value of the financial distress of manufacturing companies before and after the Covid-19 pandemic, as well as to examine the determinants that affect the financial distress of manufacturing companies before and after the Covid-19 pandemic. This study is a quantitative study with the population in this study namely manufacturing companies in Indonesia. The sample is 1005 Firm Years in manufacturing companies in Indonesia. These Manufacturing Companies were taken from 2016-2021, but we divided the sample into 2 categories, namely 2016-2019, namely in the pre-pandemic period as many as 653 firm years, and during the pandemic as many as 352 firm years. The dependent variable used in this study is financial distress, measured by the O-Score Model. Furthermore, the independent variables are profitability using ROA, liquidity using the current ratio, and leverage using the Debt to Assets Ratio. The test results show no difference between the financial distress of manufacturing companies in Indonesia before and during the pandemic. During the pandemic, financial ratios became more considered in predicting financial distress than before the pandemic. The role of profitability is a factor that impacts financial distress is more impactful in the pre-pandemic period. The role of liquidity being a factor that impacts financial distress is more impactful during the pandemic. Leverage can also be a good indicator in predicting financial distress both in the pre-pandemic and during the pandemic.
Evaluating the usefulness of punishment theories in the context of crimes committed by those in custody
Authors: Motlalekgosi Puleng 
Published: December 2022

It is inevitable and regrettable that inmates continue to commit crimes while serving their sentences. This is rather bizarre because prisons are naturally confined spaces that leave one with little or no liberty to do what one would normally do outside of prison, let alone committing crime. This raises questions concerning the pragmatic position of scientific theories that are not only formulated to explain, predict, and understand phenomena but are also seen as a bedrock of scientific research. It would not be far-fetched to expect any research paper to include a section on a theoretical framework that is essentially a representation of some level of the application of particular scholarly theories. However, not much has been documented about the usefulness of scientific theories that normally form part of research papers. This analytic paper evaluated the usefulness of scholarly theories in the criminal justice system field, specifically punishment theories, by reflecting on the crimes committed by inmates while serving their time. This study found that retribution, deterrence, and incapacitation are not useful theories in terms of theoretical scope. The incapacitation theory is not useful in terms of heuristic value, and deterrence, and rehabilitation are not useful in terms of validity.
The relationship between job satisfaction and intention to quit a job: mediating factor job burnout
Authors: Ahmad Emad , Manal Jaber  , Hussein Albanna  
Published: December 2022

The study explores the aspects of job satisfaction related to the employee's intention to quit the job in the presence of job fatigue and can help decision-makers and administrators in the Jordanian private banking sector retain highly qualified employees. The current research attempted to investigate the relationship between job satisfaction through its dimensions (satisfaction with pay, satisfaction with promotion, satisfaction with co-workers, satisfaction with emergency bonuses, satisfaction with the nature of the work, satisfaction with communication with the organization), and the intention to quit a job through its dimensions (remuneration, nature of work? Health problems and ineffective driving). The study was conducted on Jordanian commercial banks. The descriptive analytical method was used through a sample selected from the study community represented by (Alhli-Bank, Arab Bank, and Arab Islamic Bank). After conducting the tests, the study concluded that there is a significant correlation between job satisfaction in its dimensions and the intention to quit smoking. The study recommends motivating employees by reviewing wages, promotions, and emergency bonus policies in light of the results.