bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molybdenum-Mediated One-Pot Synthesis of 2-Hydroxypyrimidines from Isoxazoles
Authors: Beaumont Stéphane , Rochelle Servane 
Published: June 2023

AbstractA one-pot procedure towards substituted 2-hydroxypyrimidines from commercially available isoxazoles is reported. The process involves cleavage of the isoxazole N–O bond mediated by Mo2(OAc)4, then in situ hydrolysis of the resulting β-amino enone to the reactive 1,3-dicarbonylated intermediate, followed by hydroxypyrimidine formation in the presence of urea. Moderate to excellent yields are obtained, leading to functionalized hydroxypyrimidines. By using readily available isoxazoles, a wide range of new diverse polysubstituted hydroxypyrimidines may be prepared by this method.
DMAP-Catalyzed Domino Reactions of α-Chloroaldoxime O-Methanesulfonates and 2-Aminobenzoic Acids for the Synthesis of Quinazolinediones
Authors: Kaeobamrung Juthanat , Kaewman Watcharadet 
Published: June 2023

AbstractQuinazolinedione derivatives were obtained from 2-aminobenzoic acids and bench-stable α-chloroaldoxime O-methanesulfonates via DMAP-catalyzed domino reactions under mild reaction conditions in one-pot fashion. Chemical transformations involved nucleophilic substitution, Tiemann rearrangement, and cyclic urea formation. The strength of nitrogen nucleophile of 2-aminobenzoic acids and the high level of carbon electrophile of α-chloroaldoxime O-methanesulfonates were crucial for the reaction outcome. An application to synthesize a quinazolinedione building block was introduced.
Transition-Metal-Catalyzed Synthesis of α-Chiral Allylsilanes
Authors: Jackowski Olivier , Ferreira Franck , Pérez Sevillano Rubén 
Published: June 2023

AbstractOver the past 30 years, the synthesis of α-chiral allylsilanes have attracted much interest. These compounds are indeed versatile building blocks and linchpins ranking among the most useful organic scaffolds due to the large number of transformations that both their C–Si bond and C–C double bond can undergo. They therefore occupy a unique place in the arsenal of the organic chemist, particularly for the synthesis of complex molecules. In this review, an overview of transition-metal-catalyzed syntheses of α-chiral allylsilanes is presented.1	Introduction2	Addition of Silylmetals2.1	Silylation of Allylic Electrophiles2.2	Conjugate Addition2.3	1,2-Addition to N-tert-Butylsulfonyl Imines2.4	Silaboration3	Addition of Nucleophiles3.1	Substitution of γ-Silylated Allylic Electrophiles3.2	1,4-Conjugate Addition to β-Silyl Enones and Enoates3.3	Reduction of γ-Silylated Allylic Carbonates4	Hydrosilylation4.1	1,4-Hydrosilylation of 1,3-Dienes4.2	1,2-Hydrosilylation of 1,3-Dienes4.3	1,2-Hydrosilylation of Allenes5	Cross-Coupling Reactions5.1	Cross-Coupling of Vinyl Halides5.2	Retroallylation of δ-Silylated Homoallylic Alcohols5.3	Multicomponent Cross-Coupling of 1,3-Dienes6	Insertion Reactions6.1	Vinylcarbenoid Insertion into Si–H Bonds6.2	Silylene Insertion into Allylic C–O Bonds7	Rearrangements7.1	Intramolecular γ-Silylation of Allylic Disilanyl Ethers7.2	Domino Isomerization–Claisen Rearrangement of γ-Silylated Bis(allylic) Ethers8	Miscellaneous9	Conclusion
Synchronous Posterior and Anterior Pituitary Tumors: A Case Report of a Hypothetic Paracrine Relationship
Authors: Rubino Franco , Eichberg Daniel G. , Saad Ali G. , Komotar Ricardo J. , Ivan Michael E. 
Published: June 2023

AbstractTumors of the posterior pituitary are a distinct group of low-grade sellar neoplasms. Furthermore, the coexistence with an anterior pituitary tumor is extremely unlikely and could not be a mere coincidence and could be a paracrine relationship. Here, we present a case of 41-year-old woman with Cushing syndrome and two pituitary masses on magnetic resonance imaging. Histologic examination shows two distinct lesions. The first consisted of a pituitary adenoma with intense adrenocorticotropic hormone immunostaining and the second lesion consisted of a proliferation of pituicytes arranged in vague fascicles or pituicytoma. After a narrative review of the literature, we found that synchronous pituitary adenoma and a thyroid transcription factor 1 (TTF-1) pituitary tumor were only reported eight times in the past. These patients included two granular cell tumors and six pituicytomas and all of them coexisted with pituitary adenomas, seven functioning and one nonfunctioning. We analyze the hypothesis of a possible paracrine relationship for this concomitance, but this exceedingly rare situation is still a matter of debate. To the best of our knowledge, our case represents the ninth case of a TTF-1 pituitary tumor coexisting with a pituitary adenoma.
Mature Teratoma with Somatic-Type Malignancy: An Entity of Unacquaintance—A Case Report
Authors: Diyora Batuk , Devani Kavin , Epari Sridhar , Deshpande Gauri , Purandare Anup , Wankhade Ravi 
Published: June 2023

AbstractPrimary intracranial teratomas are nongerminomatous germ cell tumors. They are infrequent lesions along the craniospinal axis, with their malignant transformation extremely uncommon. A 50-year-old-male patient presented with one episode of generalized tonic–clonic seizure (GTCS), without any neurological deficit. Radiological imaging revealed a large lesion in the pineal region. He underwent gross total excision of the lesion. Histopathological examination was representative of teratoma with adenocarcinomatous malignant transformation. He underwent adjuvant radiation therapy and had an excellent clinical outcome. The present case highlights the rarity of malignant transformation of the primary intracranial mature teratoma.
Fracturas de Hueso Piramidal: Revisión Bibliográfica a Propósito de Cuatro Casos Clínicos
Authors: Perova Yulia , Sauras Ángel Castro , Garcia Justo Manuel Villalba , Martínez Sandra Rodríguez , García Miguel Ranera , Agustín María Royo 
Published: June 2023

ResumenLas fracturas del hueso piramidal, o triquetral, son las segundas fracturas más frecuentes de carpo después de las fracturas de escafoides. Normalmente, se producen por impactación ósea tras traumatismos en extensión y desviación cubital de la muñeca. Estas fracturas se clasifican en tres grupos: corticales dorsales, fracturas del cuerpo del piramidal y corticales volares. No es infrecuente que estas lesiones se diagnostiquen de forma tardía, ya que en muchas ocasiones pueden pasar desapercibidas en la atención en los Servicios de Urgencias. Esto se puede evitar mediante la realización de pruebas adicionales radiológicas como la tomografía computarizada (TC) de inicio. Clásicamente, se ha considerado que estas fracturas tienen buen pronóstico y se tratan mediante inmovilización. Sin embargo, la resonancia magnética (RNM) puede ser útil para el diagnóstico de lesiones asociadas en los casos de mala evolución. Recientemente, se ha discutido en la bibliografía los distintos tipos de gestos quirúrgicos a realizar según encontremos una inestabilidad carpiana, pseudoartrosis fibrosa, lesiones de complejo de fibrocartílago triangular, artrosis piso-piramidal, etc. Los objetivos de esta revisión son comparar casos clínicos en dos perfiles diferentes de pacientes que tienen evolución distinta de la misma entidad patológica, así como el de realizar una revisión completa sobre el tema aportando información adicional sobre algunas complicaciones de este tipo de fracturas.
Fracturas de Radio Distal con Lesiones Concomitantes de Codo. Un Análisis Prospectivo
Authors: Aita Marcio Aurelio , Aliberti Guilherme Murbach , Fontana Renan Martins , Biondi Bruno Gianordoli , Zaidenberg Ezequiel , de Oliveira Ricardo Kaempf , Ruggiero Gustavo Mantovani 
Published: June 2023

Resumen

Antecedentes Hoy en día es cada vez más común el politraumatismo con lesiones de codo (LC) y fracturas ipsilaterales de radio distal (FRDs), alrededor del 17,5% de todas las fracturas del adulto y se discute que el método ideal y el mejor momento para tratar lesiones de alta energía pueden tener un fuerte impacto social.
Objetivos Comparar la fuerza de agarre, los resultados radiográficos e informados por el paciente en pacientes con lesiones de codo ipsilaterales inestables y FRD con o sin inestabilidad longitudinal del antebrazo tratados en el mismo tiempo
Métodos Se incluyeron 231 pacientes con FRD, tratados durante el período comprendido entre febrero de 2018 a julio de 2021 y 18 pacientes. El período de seguimiento fue de 12 meses y 12 hombres y 6 mujeres. Los pacientes se dividieron en dos grupos: FRD asociados con LC (Grupo 1 - 6 pacientes) o sin disociación radiocubital longitudinal Grupo 2 - (12 pacientes). Los resultados clínicos y funcionales y las características radiográficas se evaluaron a los 12 meses.
Resultados A los 12 meses, se observó con respecto a la fuerza de agarre, que todos los pacientes presentaban resultados en el tercer o cuarto cuartil. Las puntuaciones DASH media fueron 3,8 y las puntuaciones EVA fueron 1,5. Once pacientes requirieron un procedimiento secundario 61% (11/18) con remover codo ex fix (5/18), spanning plate (2/18), cambiar cabeza radial ORIF (reducción abierta y fijación interna) a artroplastia (1/18). La reducción inicial de la fractura o la estabilidad articular se mantuvieron en el 94,4 % (17/18) de los pacientes.
Conclusiones Existe una relación lineal entre las lesiones de muñeca y codo y sus resultados, con o sin disociación radiocubital longitudinal. Ambos demostraron predecir la restauración de la capacidad de los pacientes para realizar actividades de la vida diaria de forma independiente. Recomendamos que las lesiones combinadas se manejen al mismo tiempo y se recomienda la fijación interna para el tratamiento definitivo de FRD/LC siempre que sea posible y mejore los resultados radiográficos e informados por el paciente.
Walant Para El Síndrome De Linburg-Comstock: Caso Clínico
Authors: Saiz Javier Coloma , Vadillo Marta Moreno , Fernández Julio Doménech 
Published: June 2023

ResumenEl Síndrome de Linburg-Comstock se caracteriza por la incapacidad para flexionar activamente la articulación interfalángica del pulgar, sin, involuntariamente, flexionar también las articulaciones interfalángicas proximal y distal del índice, debido a conexiones tendinosas entre el tendón flexor largo del pulgar, o su vientre muscular, y los tendones flexores profundos de los dedos. Presentamos el caso de una policía con esta anomalía, a la que se le indicó baja laboral, y, posteriormente, fue reubicada, por su incapacidad para empuñar el arma reglamentaria, sin que la disparase involuntariamente. Hasta la fecha, no hemos encontrado ninguna publicación en el que el uso de la técnica de cirugía mediante anestesia local sin isquemia (WALANT) se haya utilizado como método quirúrgico en el Síndrome de Linburg-Comstock.
Statistical analysis of observed Faraday wave patterns
Authors: Peña-Polo Franklin , Carvajal-Mariscal Ignacio , Vargas Carlos A. , Di G. Sigalotti Leonardo 
Published: June 2023

We present experimental observations of Faraday wave patterns when a liquid in a square recipient is submitted to vertical vibrations with forcing frequencies and amplitudes in the intervals 10 ≤ F ≤ 80 Hz and 0.1 ≤ A ≤ 3 mm, respectively. A sweep of the forcing parameter space is performed to investigate the surface patterns that form for two different sizes of the recipient. The waveforms are obtained by means of a Pearson correlation analysis of a sequence of liquid surface images for each experiment. The Pearson correlation coefficients are then fast Fourier transformed to obtain the power spectra. For 10 ≤ F ≤ 15 Hz, tessellation patterns consisting of ordered arrays of rhomboid-shaped tiles are observed; whereas, for 20 ≤ F ≤ 25, the tessellation patterns become irregular over the entire surface where square, rhomboidal, andhexagonal tilings coexist. At 30 ≤ F ≤ 45 Hz, the patterns correspond to a mixed state where ordered and irregular quadrilateral tessellation patterns coexist. At frequencies between 50 and 80 Hz, the tessellated patterns that form consist of irregularly distributed square-shaped tiles. In all cases, the excited waves are periodic with a dominant subharmonic frequency f = F/2. However, for given forcing parameters, the waveforms and their amplitudes differ markedly when the size of the recipient is changed.
Dissipative phase transition in an open Tavis–Cummings model with a two-photon drive
Authors: Adhikary Kingshuk , Müstecaplıoǧlu Özgür E , Deb Bimalendu 
Published: June 2023

Abstract
We investigate the steady-state quantum phases and associated collective phenomena of an open Tavis–Cummings (TC) model driven by a two-photon source. The standard (non-dissipative) TC model describes the quantum phases of an ensemble of N

q
two-level quantum emitters interacting with a single-mode electromagnetic field. The interplay among coherent driving, dissipation, and dipole interactions of the open TC model results in emergent collective phenomena, leading to a dissipative or non-equilibrium phase transition from the normal to the superradiant phase. We solve the Liouvillian equation analytically using the semi-classical mean-field approximation. We carry out stability analysis of the steady-state phases and determine the phase boundary. The use of Holstein–Primakoff transformation in the thermodynamic limit

N
q

→
∞

reduces the system to an effective coupled-oscillator model, the solution of which yields collective modes.
Plasmon enhancement of third-order nonlinear optical absorption of gold nanoparticles dispersed in planar oriented nematic liquid crystals
Authors: Wang Shengwei , Fu Changshuo , Sun Greg , Gharbi Mohamed Amine , Yelleswarapu Chandra S 
Published: June 2023

Abstract
We report structural and nonlinear optical properties of 20 nm gold (Au) nanoparticles (NPs) that are dispersed in planar degenerate (non-oriented) and planar oriented nematic liquid crystals (LCs) (4′-Pentyl-4-biphenylcarbonitrile-5CB). Taking advantage of elastic forces in the planar oriented nematic LC, we aligned AuNPs parallel to the 5CB director axis. In the case of planar degenerate, 5CB is not aligned and has no preferred orientation, forcing the AuNPs to disperse randomly. Results show that the linear optical absorption coefficient for the planar oriented 5CB/AuNPs mixture is larger than the corresponding planar degenerate sample. The nonlinear absorption coefficients are greatly enhanced in planar oriented samples at relatively high concentrations which can be attributed to plasmon coupling between the aligned AuNPs. This study demonstrates the utility of LCs for developing the assembly of NPs with enhanced optical properties which may offer important insight and technological advancement for novel applications, including photonic nanomaterials and optoelectronic devices.
Superlattice-like Sb70Se30/HfO2 thin films for high thermal stability and low power consumption phase change memory
Authors: Wang Kangyao , Chen Leng 
Published: June 2023

Abstract
We have fabricated Sb70Se30/HfO2 superlattice-like structure thin films for phase change memory by magnetron sputtering method, and investigated the effect of the HfO2 layer on the crystalline characteristics and phase change behavior of Sb70Se30/HfO2 thin films. The experimental results show that as the HfO2 thickness increases, the crystallization temperature rises, the data retention capacity increases as well as the band gap widens, which is beneficial for improving the thermal stability and reliability of Sb70Se30/HfO2 thin films. It was also found that the HfO2 composite layer inhibited the grain growth of the Sb70Se30 thin film, reducing the grain size and resulting in a smoother surface. In addition, the volume fluctuation of the Sb70Se30/HfO2 thin films changes by only 5.58% between amorphous and crystalline. The threshold and reset voltages of the cell based on Sb70Se30/HfO2 thin films are 1.52 V and 2.4 V respectively. We found that the HfO2 composite layer plays a significant role in improving thermal stability, refining grain size of Sb70Se30 phase change films and reducing device power consumption.
Investigation into the effects of hydrophobicity on thermohydraulic characteristics and entropy generation of hybrid nanofluid with the magnetic property in a micro-heat sink under a magnetic field
Authors: Derikvand Mohammad , Salehi Ali Akbar , Solari Mojtaba Shams , Najafi Fatemeh 
Published: June 2023

Abstract
The cooling of devices is a big challenge in the electronics industry, and most process units (graphical are central process units) experience defects under harsh temperature conditions, so dissipating generated heat under various working conditions should be studied seriously. This study investigates the magnetohydrodynamics of hybrid ferro-nanofluids in the presence of hydrophobic surfaces in a micro-heat sink. To scrutinize this study, a finite volume method (FVM) is applied. The ferro-nanofluid includes water as a base fluid and multiwall carbon nanotubes (MWCNTs) and Fe3O4 as nanoadditives, which are used in three concentrations (0, 1, and 3%). Other parameters such as the Reynolds number (5–120), Hartmann number (magnitude of the magnetic field from 0 to 6), and hydrophobicity of surfaces are scrutinized for their impacts on heat transfer and hydraulic variables as well as entropy generation variables. The outcomes indicate that increasing the level of hydrophobicity in surfaces leads simultaneously to improved heat exchange and reduced pressure drop. Likewise, it decreases the frictional and thermal types of entropy generation. Intensifying the magnitude of the magnetic field enhances the heat exchange as much as the pressure drop. It can also decrease the thermal term in entropy generation equations for the fluid, but increase the frictional entropy generation and adds a new term, magnetic entropy generation. Incrementing the Reynolds number improves the convection heat transfer parameters, although it intensifies the pressure drop in the length of the channel. Also, the thermal entropy generation and frictional entropy generation decrease and increase with an increasing flow rate (Reynolds number).
Graphene's effect and mechanism on the properties of alkali-activated slag coating
Authors: Wang Siming , Luo Xiang , Hua Sudong , Zhang Yanan , Chen Tingzhu 
Published: June 2023

Abstract
Using alkali-activated slag to prepare coatings is an alternative solution for concrete repair and protection. However, shrinkage cracking limits the application of alkali-activated slag, which also increases the risk of coating peeling. Graphene dispersions (content of 0.2%, 0.4%, 0.6% and 0.8%) were added to the alkali-activated slag coatings. The drying time, apparent circumstance (thicknesses of 1 mm, 2 mm, 3 mm and 5 mm) and the tensile bond strength with 1 mm thickness coating were determined. The mechanism of action was analyzed in terms of both product and interfacial properties. The experimental results showed that the graphene dispersion would shorten the drying time of the coatings. The drying time was reduced by 57.1% (from 116 min to 52 min). Moreover, the graphene dispersion improves the cracking of the coating. The larger the coating thickness is, the better it improves the cracking effect. The surface cracking of the coating with 5 mm thickness was reduced by 60.7% (from 1.6751% to 0.6583%). Graphene can significantly improve the bond strength of the coating. When the graphene content is 0.8%, the bonding strength with a thickness of 1 mm is 0.502 MPa at 7 days and 1.577 MPa at 28 days. The bond strength increased by 280.3% and 175.2%, respectively, XRD, FTIR and SEM analysis showed that the increase in bond strength was caused by two factors. (1) Graphene can promote the generation of zeolite phase in alkali-activated slag. This is conducive to enhancing the interlayer adhesion of the coating itself. (2) Graphene is beneficial to reduce the pores in the transition zone between the coating and the substrate and enhance the contact area between the coating and the substrate and makes the transition zone denser.
CYJAX: A package for Calabi-Yau metrics with JAX
Authors: Gerdes Mathis , Krippendorf Sven 
Published: June 2023

Abstract
We present the first version of CYJAX, a package for machine learning Calabi–Yau metrics using JAX. It is meant to be accessible both as a top-level tool and as a library of modular functions. CYJAX is currently centered around the algebraic ansatz for the Kähler potential which automatically satisfies Kählerity and compatibility on patch overlaps. As of now, this implementation is limited to varieties defined by a single defining equation on one complex projective space. We comment on some planned generalizations.
More documentation can be found at: https://cyjax.readthedocs.io.
The code is available at: https://github.com/ml4physics/cyjax.
Cardiogenic shock and severe secondary mitral regurgitation successfully treated with transcatheter edge-to-edge repair: a case report
Authors: Shabbir Muhammad Asim , Tiwari Nidhish , Burdorf Adam , Moulton Michael , Velagapudi Poonam 
Published: June 2023

Abstract

Background
Cardiogenic shock (CS) associated with severe mitral regurgitation (MR) forebodes a high risk of morbidity and mortality. Transcatheter edge-to-edge repair (TEER) is a rapidly evolving technique for severe MR in haemodynamically stable patients. However, the safety and efficacy of TEER for severe MR in CS are not well established.

Case summary
An 83-year-old male presented with dyspnoea and was hospitalized for heart failure. Chest X-ray revealed pulmonary oedema. Transthoracic echocardiography showed severely depressed ejection fraction (EF) with severe secondary MR. Right heart catheterization confirmed a low cardiac index. Diuretics and inotropes were administered. Due to persistent hypotension, we could not wean inotropes. The patient was deemed high risk for surgery by the heart team, and a decision was made to proceed with TEER with MitraClip. Under transoesophageal echocardiography and fluoroscopic guidance, two MitraClips were deployed sequentially. The MR grade was reduced to two mild jets subsequently. The patient was weaned off inotropes and eventually discharged. At the 30-day follow-up, he was participating in physical activities such as golf.

Discussion
Cardiogenic shock complicated by severe MR carries high mortality. With severe MR, the forward stroke volume is lower than the stated EF leading to poor organ perfusion. Inotropes and/or mechanical circulatory support devices are paramount for initial stabilization; however, they do not treat underlying MR. Transcatheter edge-to-edge repair with MitraClip has been shown to improve survival in CS patients with severe MR in observational studies. However, prospective trials are lacking. Our case demonstrates the utility of MitraClip to treat severe secondary MR refractory to medical therapy in a CS patient. The heart team must evaluate risks and benefits of this therapy in CS patients.