bluuebunny/crossref_metadata_2025_split huggingface dataset:
Limitación al acto de fiscalización en los periodos prescriptos en la ley 125/1991 del Paraguay
Authors: Cordeiro Candido Joelma 
Published: May 2023

La propuesta de este estudio es un análisis del instituto jurídico de la prescripción en la legislación tributaria del Paraguay Ley 125/1991 “Que Establece el Nuevo Régimen Tributario”[1], su alcance en cuanto a la limitación de las facultades de fiscalización y determinación de la obligación tributaria en periodos que se hallan prescriptos, considerando los fundamentos de la confianza legítima y la buena fe que se desprenden del principio de seguridad jurídica en el cual se ancla el instituto de la prescripción. El estudio se desarrolló con un enfoque cualitativo y el nivel de investigación fue descriptivo y la técnica de recolección de datos fue a través de la observación de documentos apoyándose en una lista de cotejos.

[1] Antes de la vigencia de la Ley 125/1991, el sistema tributario del Paraguay era anacrónico y con diversos impuestos estructurados de forma desordenada que resultaba complejo e incoherente a la vez, no respondía a un objetivo de política fiscal y desarrollo económico, además representaba una recaudación insuficiente. Luego con la reforma de la Ley 125/1991 se alineó la normativa tributaria a las de la región estableciendo cuatro categorías de impuestos; a los ingresos, al consumo, al capital y otros tipos de impuestos.
AKTIVITAS ANTIOKSIDAN DAN KANDUNGAN TOTAL FENOLIK PADA EKSTRAK TERIPANG (Holothroidea)
Authors: Husain Fadli , Yunus Fitriah Ayu Magfirah , Basri Insyira Fadliana 
Published: May 2023

Radikal bebas adalah senyawa yang memiliki sifat reaktif. Senyawa ini mudah bereaksi dengan molekul lain dengan cara mengoksidasi sehingga dapat menimbulkan pengaruh negatif terhadap tubuh antara lain mengakibatkan kerusakan lipida, protein, DNA dan membran sel. Adanya radikal bebas menyebabkan tubuh membutuhkan zat penting yang dapat menangkap radikal bebas, yaitu antioksidan. Senyawa antioksidan merupakan zat yang dapat mencegah terjadinya proses oksidasi. Teripang merupakan salah satu produk laut yang memiliki aktivitas antioksidan. Senyawa yang terdapat pada teripang telah dibuktikan secara ilmiah dapat meredam radikal bebas yang menyebabkan berbagai penyakit degeneratif. Beberapa senyawa diantaranya adalah triterpen glikosida (saponin), kondroitin sulfat, glycosaminoglycans (GAGs), fenolik, dan asam lemak esensial. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dan kandungan fenolik total dalam ekstrak teripang yang berasal dari perairan Patoameme Kab. Boalemo Gorontalo. Penelitian ini merupakan jenis penelitian eksperimental laboratorium yang akan dilaksanakan di Gorontalo dan Makassar. Hasil yang didapatkan bahwa ekstrak etanol teripang mengandung senyawa fenol dan flavonoid, serta hasil pengujian aktivitas antioksidan yang diuji dengan metode ABTS, BCB, dan DPPH menunjukkan hasil IC50 berturut-turut yaitu 91,4 µg/mL, 152,91 µg/mL, 233,6 µg/mL. Sedangkan pada metode FRAP menunjukkan bahwa ekstrak etanol teripang memiliki kemampuan dalam mereduksi besi sebesar 7,629±0,10 QEAC/g ekstrak.
Kata kunci : teripang, antioksidan, fenolik, DPPH
KARAKTERISASI DAN STUDI PENAPISAN FITOKIMIA DAUN KELOR (Moringa oleifera L.) ASAL GARUT JAWA BARAT
Authors: Aji Najihudin  , Siti Hindun  , Rantika Nopi , Ghina Magfiroh  , Sujana Dani 
Published: May 2023

Tanaman kelor (Moringa oleifera L.) digunakan oleh masyarakat sebagai obat tradisional dan diyakini memiliki potensi untuk mengatasi malnutrisi serta mencegah dan menyembuhkan berbagai penyakit. Sebagai calon bahan baku obat, karakteristik merupakan langkah awal untuk mengetahui mutu dari simpilia, sehingga hasilnya dapat dijadikan acuan pengembangan penelitian selanjutnya. Tujuan dari karakteristik simplisa dalam upaya pemenuhan persyaratan dan menjamin konsistensi mutu untuk memenuhi standar yang telah ditetapkan sebagai bahan baku obat tradisional. Penelitian ini melaporkan bahwa serbuk simplisia daun kelor memiliki nilai kadar air 4,0%, kadar abu total 6,47%, kadar abu larut air 1,69%, kadar abu tidak larut asam 0,73%, kadar sari larut air 38%, kadar sari larut etanol 18% dan susut pengeringan 6,5%. Rendemen ekstrak yang diperoleh adalah 13,58%, sedangkan hasil penapisan fitokimia dari simplisia dan ekstrak daun kelor menunjukkan hasil yang konsisten antara kandungan alkaloid, flavonoid, tanin dan kuinon, akan tetapi saponin dan steroid/triterpenoid justru tidak terdeteksi setelah perlakuan ekstraksi. Jenis dan konsentrasi fitokimia pada tanaman sumber berbeda-beda tergantung faktor internal dan eksternal seperti jenis tanaman, varietas, tanah, dan lingkungan tumbuh (luas, ketinggian, dan musim). Saponin diklasifikasikan sebagai saponin steroid atau triterpenoid tergantung pada sifat aglikon, yang dikenal sebagai sapogenin. Selama ekstraksi, saponin dapat terhidrolisis dan terdegradasi, sehingga harus sangat berhati-hati selama ekstraksi. Selain itu, struktur kimia saponin dapat berubah selama penyimpanan atau pengolahan. Ikatan antara rantai gula dan aglikon serta antara gugus gula dapat dihidrolisis dengan perlakuan asam atau basa, dihidrolisis atau diubah oleh enzim/mikroorganisme, mengarah pada pembentukan aglikon, prosapogenin (saponin yang dihidrolisis sebagian) dan residu gula...
Did the COVID-19 Pandemic Period Increased Suicide Attempts in Society?
Authors: UZUN Ahmet , ÇEKMEN Bora 
Published: May 2023

Aim: To analyze the influence of the COVID-19 pandemic and quarantine on suicidality.
Material and Methods: This study was conducted on patients over the age of 15 who were suicidal and admitted to the emergency department of our hospital. The patients were disunited into two groups: pandemic group covering the period from March 11, 2020 to March 11, 2021, the former being the date when the first patient of COVID-19 was identified in Turkey, and pre-pandemic group covering the period from March 11, 2019 to March 10, 2020.
Results: The study was conducted with a total of 271 patients. The number of suicide attempts in the first time period (March-April-May-June) was 42 (28.4%) in the pandemic group and 16 (13.0%) in the pre-pandemic group, with significantly higher numbers in the pandemic group for the first time period (p=0.008). The distribution in the remaining second and third time periods was similar to those in the previous year.
Conclusion: Compared to the pre-pandemic period, suicide attempts significantly increased in the early stages of the pandemic as the first case was identified in Turkey and the lockdown was imposed because of the increasing cases. In the later stages of the pandemic, there was no obvious change in the amount of suicide compared to previous periods.
Gambaran Kepatuhan Mencuci Tangan dalam Pencegahan COVID-19 Pada Masyarakat Di Kabupaten X
Authors: Khumala Sari Nur 
Published: May 2023

Penelitian ini dilakukan untuk mengetahui tingkat kepatuhan mencuci tangan dimasa pandemi Covid-19 oleh masyarakat. Metode penelitian yang digunakan adalah metode kuantitatif deskriptif dengan teknik pengumpulan data melalui kuesioner. Alat ukur yang digunakan yaitu skala kepatuhan. Subjek penelitian yaitu 125 orang yang bekerja dan bertempat tinggal di Kabupaten Lima Puluh Kota. Sampel penelitian diambil dengan menggunakan teknik accidental sampling. Analisis data dilakukan menggunakan program IBM SPSS 22 for Windows. Penelitian ini menunjukkan bahwa kepatuhan masyarakat di Kabupaten Lima Puluh Kota dalam perilaku mencuci tangan sangat baik dengan persentase 79%.
Gambaran Psychological Well Being pada Dewasa Awal Yang Berstatus Janda di Kenagarian Air Bangis
Authors: Yenita Sri 
Published: May 2023

Psychological well being adalah evaluasi individu atas aktivitas kehidupannya berupa pengungkapan perasaan-perasaan pribadi terhadap apa yang dirasakan sebagai hasil dari pengalaman hidup dan berfungsi secara efektif dalam kehidupan dan menjalaninya dengan bahagia. Penelitian ini bertujuan untuk melihat gambaran psychological well being pada wanita dewasa awal yang berstatus janda pasca bercerai di Kenagarian Air Bangis. Penelitian ini dilakukan pada janda dewasa awal dengan pendekatan kualitatif menggunakan metode deskriptif. Teknik analisis data yang digunakan dalam penelitian adalah analisis deskriptif. Penelitian ini berhasil mengidentifikasi aspek psychological well being menurut Ryff (1989). Kedua partisipan mampu menerima kondisi dirinya sebagai janda pada masa dewasa awal dan melewati kesedihannya dengan mendapat dukungan dari kelurga.
Very Metal-poor Stars in the Solar Vicinity: Kinematics and Abundance Analysis
Authors: Plotnikova Anastasiia , Carraro Giovanni , Villanova Sandro , Ortolani Sergio 
Published: May 2023

Abstract
Very metal-poor stars contain crucial information on the Milky Way’s infancy. In our previous study we derived a mean age of ∼13.7 Gyr for a sample of these stars in the Sun’s vicinity. In this work, we investigate the chemical and kinematic properties of these stars with the goal of obtaining some insights into their origin and their parent population. We did not find any Al–Mg anticorrelation, which leads us to the conclusion that these stars did not form in globular clusters, while the detailed analysis of their orbital parameters reveals that these stars are most probably associated with the pristine bulge of the Milky Way. We then sketch a scenario for the formation of the Milky Way in which the first structure to form was the bulge through rapid collapse. The other components have grown later on, with a significant contribution of accreted structures.
Les ouvriers vivent moins longtemps que les cadres : combien de temps passent-ils à la retraite et en (in)activité ?
Authors: Bonnet Florian , Camarda Carlo-Giovanni , Cambois Emmanuelle , Merville Ophélie 
Published: May 2023

En 2018, l’espérance de vie à 35 ans des hommes cadres est de près de 50 ans, contre 44 ans pour les ouvriers, soit presque 6 ans d’écart. Ces écarts d’espérance de vie sont encore importants à 62 ans : 3 ans et 6 mois ans chez les hommes, 2 ans et 8 mois chez les femmes. En dépit d’un départ à la retraite plus précoce, les ouvriers passent 2 années de moins à la retraite que les cadres et 3,4 années de plus au chômage ou en inactivité. Par ailleurs, les années de chômage ou d’inactivité sont fréquentes dans les années précédant l’âge légal pour les ouvriers. Les femmes passent de 3 à 4 ans de plus à la retraite que les hommes de catégorie sociale similaire, mais aussi plus d’années qu’eux en inactivité.
Vers la construction d’une grille d’analyse des conflits interpersonnels au sein des organisations : une étude de cas sous le prisme des théories de l’Ecole de Palo Alto.
Authors: Valitova Aysylu 
Published: May 2023

Dans cet article, nous montrons la pertinence des catégories conceptuelles de l’analyse systémique de l’Ecole de Palo-Alto pour l’étude des conflits interpersonnels à partir d’une synthèse de la littérature sur les conflits, leur gestion et leurs types. Nous proposons d’articuler ses concepts analytiques avec l’actualisation des histoires de vie et l’internalisation des contextes, au sens de l’ habitus de Bourdieu. Ce canevas conceptuel est ensuite mobilisé comme grille d’analyse d’un cas au sein d’une université canadienne se déroulant en deux temps : un conflit interpersonnel de harcèlement débouchant sur un conflit entre le service de gestion des conflits et le syndicat du personnel. L’analyse systémique des relations a permis de comprendre le conflit interpersonnel en termes de schismogenèse symétrique puis de « complémentarité rigide » créatrice d’une forme d’emballement relationnel. L’analyse systémique des relations entre de nouveaux syndicalistes et des membres de la direction de l’université montre une schismogenèse positive et permet de saisir pourquoi et comment s’est produite une rupture institutionnelle autorisant l’émergence d’une coopération afin de prévenir ou résoudre les conflits interpersonnels.
Science and scientists under attack
Authors: De Stefano Valerio 
Published: May 2023

It has happened, therefore it can happen again (Primo Levi)

Dear Editor,A recent Editorial published in your journal illustrated the condition of Ukrainian scientists during the invasion of their country by the aggressor Russian Federation: killed, at the front, or refugees. Just as the international democratic community supports Ukraine from the attack and already plans reconstruction, the scientific community is urged to support its Ukrainian colleagues and their scientific networks.
School Examination Stress Precipitating Hematohidrosis in a Girl
Authors: Vikram Anupama , Christy Maria Viagulum. J , Varadarajan Poovazhagi 
Published: May 2023

Background:
Hematohidrosis is a rare clinical disorder characterized by transient, self-limited bleeding from the eccrine sweat glands through intact skin in the absence of an underlying bleeding disorder.

Clinical Description:
We report a 10-year-old girl who presented with a history of bleeding from the dorsum of her right hand. The child has had recurrent episodes in the past. Many of the episodes were temporally related to her school examination. She did not have any other bleeding manifestations or susceptibility to bruising. Her general condition and systemic examination were unremarkable, and the skin underlying the bleeding site was normal and healthy. All investigations related to bleeding and coagulation parameters were within normal limits. Skin biopsy showed normal histology. Having ruled out all organic causes of bleeding, the typical history of transient episodes of bloody secretions from the skin, triggered by examination stress and normal skin histology, was consistent with a diagnosis of hematohidrosis.

Management:
The child responded dramatically to oral propranolol with a subsequent reduction in the frequency of the bloody sweating episodes, even during stressful times. Psychological counseling was also provided.

Conclusion:
In a child presenting with oozing of blood from the skin, a possibility of hematohidrosis may be considered, when all causes of bleeding diathesis have been ruled out by a thorough workup. Pediatricians need to counsel both parents and the child regarding the benign nature of the condition.
Factors Affecting the Efficacy of Botulinum Toxin Injection in the Treatment of Infantile and Partially Accommodative Esotropia
Authors: Alarfaj Motazz A. , Alsarhani Waleed K. , Alrashed Saleh H. , Alarfaj Faris A. , Ahmad Khabir , Awad Abdulaziz , Sesma Gorka 
Published: May 2023

Abstract

PURPOSE:
We aimed to investigate the effect of botulinum toxin (BT) injection on the treatment of infantile and partially accommodative esotropia (PAET).

METHODS:
This retrospective cohort study included patients who received BT injections for infantile and PAET between January 2015 and December 2018. Treatment was considered successful if orthotropia, consecutive exotropia, or esotropia within 10 prism diopters (PD) was achieved.

RESULTS:
The overall success rate was 47.4%, with a mean follow-up period of 27.8 months in 403 children. BT treatment was considered successful in 37.1% of cases of infantile esotropia and 53.1% of cases of partially accommodative esotropia. The average deviation angle before starting treatment was 35.5 ± 13.9 PD. Side effects 1 week after BT injections included transient overcorrection (63.8%) and transient ptosis (41.7%). There were no significant differences in the success rates between the different doses of BT (P = 0.69). The angle of deviation at presentation was significantly associated with the success rate of BT injection (failed group, mean: 38.1 ± 15.3 PD vs. success group, mean: 32.6 ± 11.6 PD; P < 0.001). Other factors associated with higher success rates were overcorrection at 1 week and PAET, while multivariate logistic regression analysis showed that a smaller angle of deviation and overcorrection (1 week after injection) were associated with a higher success rate.

CONCLUSION:
A smaller angle of deviation and transient overcorrection were associated with a higher success rate, and no significant difference was observed in the success rates of different BT doses.
PEMANFAATAN MEDIA PAPAN KOTAK DALAM MENINGKATKAN HASIL BELAJAR MATEMATIKA PADA MATERI SATUAN BERAT KELAS 2 MIN 2 BANGKALAN
Authors: Tamalla Maulidina , Setyawan Agung 
Published: May 2023

Based on initial data in class 2 MIN 2 Bangkalan, problems were found in learning mathematics in the unit weight material, namely students' lack of understanding due to the absence of learning media, so students were not active, bored and did not even master the material. This factor resulted in low student learning outcomes. By applying a gridboard learning media is an alternative solution to overcome problems in learning mathematics unit weight class 2 MIN 2 Bangkalan. The purpose of this study was to find out 1) the process of using square board media in mathematics lessons on weight units and 2) improving student learning outcomes on weight unit material through the use of square board media.
The type of research used is classroom action research (CAR), which has 2 cycles. Each cycle consists of planning, implementing, observing and reflecting. The research location was MIN 2 Bangkalan, Labang District, Bangakalan Regency which was conducted from February to March 2023. The research used a quantitative approach. Data collection techniques used are tests, observation and documentation. The research instrument was in the form of student learning outcomes test sheets. The subjects of the study were all 2nd grade students for the 2022/2023 academic year, totaling 28 students, consisting of 12 male students and 16
female students.

Journal homepage: https://ejurnal.univamedan.ac.id/index.php/jkpm/index

The results showed that the use of blackboard media can improve student learning outcomes that achieve scores above KKM (76) with a percentage of complete learning outcomes, pre-cycle 39.29% with an average score of 66.4, Cycle I 57.14% with an average score of 76 and Cycle 2 100% with an average of 90. Based on the research it can be concluded that learning mathematics in units of weight with the use of media unit weight boxes can be successful, so that it can be
used as an alternative solution to improve mathematics learning in MIN 2 Bangkalan
ASSOCIATION OF DOUBLE ELEVATOR PALSY WITH JAW WINKING PTOSIS
Authors: MUHAMMAD MOIN  
Published: May 2023

Purpose: To determine the association of double elevator palsy with jaw winking ptosis.
Study Design: Interventional case series.
Place & Duration of Study: Mayo Hospital, Lahore between 2000 and 2003 by one surgeon.
Material & Methods: Seventy patients with congenital ptosis were managed with Frontalis Fascia lata sling Surgery with or without vertical muscle surgery. Pre-operative visual acuity, margin to reflex distance in primary gaze (MRD1), margin to reflex distance in down gaze (MRD2), levator function, extra-ocular movements, bell’s phenomenon and jaw winking phenomenon were noted in all cases. Post-operative MRD1, MRD2, lagophthalmos and corneal surface were also noted.
Results: Review of 70 cases with congenital ptosis showed that 8 (11%) patients had jaw winking ptosis and 10 (14%) patients had double elevator (DE) palsy. Out of these 8 patients with jaw winking ptosis, 4 (50%) patients had DE palsy. Thus 6% of the total patients had both jaw winking ptosis and DE palsy.
Conclusions: This study shows that we must be very careful to eliminate double elevator palsy in cases of jaw winking ptosis due to their strong association
FREQUENCY OF RAISED CRP IN ACUTE HEART FAILURE
Authors: Dr Shoaib Sarwar  , Rashid Junaid 
Published: May 2023

C-reactive protein (CRP) is a marker for cardiovascular and cerebrovascular diseases. It is also proven that it has role in long-term development of heart failure and mortality in patients with cardiovascular diseases.
Objective: To analyze the CRP levels in patients presenting with acute heart failure and determine the frequency of patients with raised CRP levels.
Material and Methods: This cross-sectional study was conducted at Punjab Institute of Cardiology for a period of six months after approval from the hospital ethical committee. Three hundred and forty-five patients presenting with acute heart failure were taken. After Informed consent, their venous blood samples were drawn for measurement of CRP levels. All the data was collected on a predefined proforma. The data was entered and analyzed in SPSS Ver. 23.0.
Results: The mean age of patients was 45.5 l ± 10.64 years. There were 192 (55.7%) males and 153(44-3%) females. The mean duration of heart failure was 6.46 ± 3.53 hours. The mean CRP in these cases was 6.27 ± 4.70 mg/L. There were 153(44.3%) patients who had raised CRP while 192(55.7%) patients had normal CRP levels.
Conclusion: Increased CRP levels were seen in high number of cases and this may be established as significant risk factor for in hospital mortality. Particular attention should be given for prior management in presence of raised CRP.
COMPARISON THE EFFECTIVENESS OF SITAGLIPTIN VERSUS SULFONYLUREA FOR MANAGEMENT OF PATIENTS WITH TYPE II DIABETES MELLITUS
Authors: Nauman Dawood  , Mian Sajjad Ahmad  , Zafarullah Lashari  , Kamran Yousaf  , Somia Iqtadar  
Published: May 2023

Background: Type 2 diabetes mellitus (T2DM) is characterized by prolonged hyperinsulinemia, insulin resistance, and progressive hyperglycemia. Current guidelines for treating patients with T2DM are based on glycemic standards. Sitagliptin seems to maintain its positive effects on glycemia and fasting plasma insulin on the long term as compared to sulfonylurea.
Objective: To compare the effectiveness of sitagliptin versus sulfonylurea for management of patients with type II diabetes mellitus
Methods: it was randomized controlled trial. The data was collected in North medical ward, department of medicine Mayo hospital Lahore. The patients were randomly divided into two groups e.g Group A Sitagliptin and group B sulfonylurea. The blood sample were drawn at baseline and after 12 weeks for HbA1c level.
Results: In Sitagliptin group, the mean age of patients was 57.93±13.10years. In sulfonylurea group, the mean age of patients was 63.51±11.23years. There were 35 (50.0%) male and 35 (50.0%) females in Sitagliptin group. There were 31 (44.3%) male and 39 (55.7%) females in sulfonylurea group. There was 1.19±1.00% decrease in HbA1c with sitagliptin and 0.53±0.31% with sulfonylurea. The difference was significant (p<0.05). In our trial, effectiveness was achieved in 50 (71.4%) with sitagliptin while in 33 (47.1%) with sulfonylurea. The difference was significant (p<0.05).
Conclusion: Thus, Sitagliptin is more effective and control more HbA1c than sulfonylurea for management of T2DM