bluuebunny/crossref_metadata_2025_split huggingface dataset:
Great Kazakh thinker Abai and Azerbaijan
Authors: Habibbayli Isa 
Published: June 2023

The article deals with hard and honourable way of life of an outstanding classic of the Kazakh literature, great Kazakh poet and thinker Abai Kunanbay (1845-1904) who reflected national-spiritual values of Kazakh people. It is mentioned that the years of study in Semipalatinsk were of special importance in the formation of Abai Kunanbayev's outlook. Abay, who studied at a madrasa on his father’s advice, learnt Arabic and Persian, but later dropped out and got an opportunity to study the rich Russian literature and culture at a Russian school in Semipalatinsk. Writing poems that glorify the people’s spirit caused him to be persecuted by the authorities.However, in spite of all this, he sought the way of prosperity of the people only in enlightenment, in national-spiritual self-awareness. Abai's first poem, written when he was 10 years old – "Chasing a camel" – tells about his great talent. The social themes reflected in his poems are similar to the problems expressed in 19th century Azerbaijani literature from Abbasgulu agha Bakikhanov to Gasim bey Zakir and Seyid Azim Shirvani. The peak point of Abai Kunanbayev's creative work was considered his novel “Agliyya” (“Black Words”). This novel reflects the whole evolution processes from Abai's moral theory to enlightened realism.The article also touches on the points that connect the life and work of Abai Kunanbayev with Azerbaijan. It is also noted that Nizami Ganjavi and Mahammad Fuzuli has an important role in forming his worldview. Translation work in Abai Kunanbayev’s activity who has a wide range of other creative activities also has a special place. He liked Alexander Pushkin's novel “Eugene Onegin” and popularized many parts of this work among the Kazakh people by repeating. Books and articles published in Azerbaijan are essential contributions of Azerbaijani science and literary and social thought to Abai studies.

References
Heydər Əliyev. Ədəbiyyatın böyük borcu və amalı. (tərtib edəni V.Quliyev). Bakı: Ozan, 1999.
Abay. Əsərləri (tərtib edəni Fatimə Dursunova). Bakı: Mütərcim, 2017.
Anar. “Ağaclar quruyub qocalar kimi”… “Ədəbiyyat qəzeti”.
Xəlil Rza. Bədii söz nəhəngi. “Kommunist” qəzeti, 28 sentyabr, 1977.
Pənah Xəlilov. Ön söz. Bax: Abay. Əsərləri. Bakı: Mütərcim, 2017.
Turan Teymur. Muxtar Auezovun “Abay” romanında sənətkarlıq məsələləri. Qazaxıstan: Nur-Sultan, BTA, 2020.
The Existential Prophecy of Fyodor Tyutchev's Historiosophical Thought
Authors: Mysovskikh Lev Olegovich 
Published: June 2023

The article examines the historiosophical reflections of F. I. Tyutchev, presented in his treatises, letters, poems, and substantiates the idea that Tyutchev does not proclaim slogans of either Slavophil or Westernist doctrines, but creates an original imperial ideology. Tyutchev views Russia as an equal and integral part of Europe, linking the existence of the empire with the development of the European spirit in Russia. The main criterion for the existence of the empire is unity. If it does not exist, then the state as an empire cannot exist. Tyutchev treated Orthodoxy as a historiosophical category. He bases his concept of the historical process on the traditions of Eastern Christianity and the legacy of the Byzantine Empire. In the idea of an empire based on Christian principles, Tyutchev sees the best system of statehood. For Tyutchev, the Russian people and Orthodoxy play a major role in the transformation of the world. In the concept of state and power, the categories of Christian ethics are especially important for Tyutchev, which, in his opinion, were not really relevant for the upper strata of society and representatives of the Russian government. The poet calls power "godless", claiming that it does not come from God, but is based on its material power, without recognizing a higher Divine authority over itself. The reason for the "godlessness" of the authorities was the separation from the Russian people and their national traditions and the departure from the historical past of "Holy Russia". This, from Tyutchev's point of view, is the main existential problem of Russia. Tyutchev's concept of empire was not a reproduction of the realities of the political life of Russia in the XIX century, but was an attempt to answer how the state should be built. Tyutchev's ideal of the Russian state is based on a society united by a single Christian faith.
Analysis of Intercultural Education Policies in Italy and Spain: A Comparative Perspective
Authors: León Sánchez Mario , Fiorucci Massimiliano , Catarci Marco , González Monteagudo José 
Published: June 2023

This article focuses on the evolution of intercultural education in the educational policies of Italy and Spain. The evolution of school regulations and educational practices in both countries presents similar characteristics, including the shift from the paradigm of integration to that of inclusion of students with migrant backgrounds. At the same time, historical and political differences between the two countries have led to the implementation of very different practices, which it is interesting to compare, with a particular interest in those processes of hidden exclusion that are still present in the two educational systems, despite the progress of official regulations. We will present the critical points and strengths of both countries’ systems, identifying, on the one hand, the inclusion factors (development of inclusive practices, development of resources and programmes for foreign students) and, on the other hand, the exclusion practices that persist despite legislation (school segregation and school concentration). In the conclusions, we will suggest possible strategies to contribute to the development of intra-European measures and policies to foster the reception of people with a migrant background in national school systems.
Exploring the Influence of Parental Literacy Status on the Implementation of Dance Movement Therapy for Motor Skill Development in Children with Intellectual Disability in India
Authors: Nanda Anita , Rizwaan Mohammad , Mohapatra Bibhuti Bhusan , Das Pranakrushna , Padhy Archana Kumari 
Published: June 2023

This paper focuses on examining the influence of parental literacy status in the implementation of Dance Movement Therapy (DMT) for the development of motor skills in children with intellectual disabilities in India. The study aims to explore the potential impact of parental literacy on engagement, participation, and outcomes of DMT interventions, ultimately informing strategies to optimize therapy effectiveness. The research incorporates the use of the Behavioral Assessment Scales for Indian Children with Mental Retardation (Basic-MR, Part A) to assess the impact of parental literacy on the outcomes of DMT interventions.
Literacy status of parents, particularly in low- and middle-income countries like India, can significantly affect various aspects of a child's development, including their access to education, healthcare, and therapies. However, there is limited research exploring the specific role of parental literacy in the context of DMT interventions for children with intellectual disabilities in India.
This study adopts a mixed-methods research design, combining quantitative measurements and qualitative insights. A sample of children with intellectual disabilities, aged between 7 and 15 years, will be recruited from special education schools from Odisha, India. The DMT intervention will be carried out over a designated period, with trained dance movement therapists tailoring the sessions to meet the individual needs and abilities of the children. The impact of the intervention will be evaluated using the Behavioral Assessment Scales for Indian Children with Mental Retardation (Basic-MR, Part A), which provides a comprehensive assessment of motor skills including locomotor and object control skills. Quantitative data, including pre- and post-intervention assessments, will be analyzed to determine the influence of parental literacy on motor skill development outcomes.
This study aims to enhance our understanding of how parental literacy status influences the implementation of DMT and motor skill development in children with intellectual disabilities in India. By recognizing the impact of parental literacy and addressing potential challenges, the study aims to optimize the effectiveness of DMT interventions for children with intellectual disabilities. The findings will have practical implications for therapists, educators, policymakers, and other stakeholders involved in culturally sensitive intervention programs, promoting comprehensive motor skill development in children with intellectual disabilities in India.
Evaluation of Results of Separate Vertical Wirings for the Treatment of Extra-articular Fractures of the Distal Pole of the Patella
Authors: Uddin Mohammad Shah Kamal , Talukder Tutul , Hussain Muhammad Amzad , Marma Ushahla , Harun-Ar-Rashid A. K. M. , Tareen Mohammad Ridowan , Ali Md. Ayub 
Published: June 2023

Background: Patella connects quadriceps ligament and tendon. Base peak. proximal non-articular distal patella. Common subcutaneous patella injurie. Patella focuses Quadriceps forces and facilitates arm extension. It rotates the knee extensor. At maximum extension, the patella raises the quadriceps moment arm by 30%. Patellar avulsion fractures are classified independently. 9.3% to 22.4% of patellar fractures are thus. AO 34-A1 extra-articular lower pole fractures. Rapid flexion against quadriceps contraction causes this fracture. After bone removal, the patellar tendon is frequently sutured transosseously. Long fixation and sluggish recovery cause quadriceps weakness. Two of 25 patients had problems with poor vertical wirings. We examined 2 vertical wiring procedures for extra-articular distal patella fractures.
Objective: To look at how well separate vertical wirings work for treating fractures outside of the joint at the end of the patella.
Methods: Prospective, observational study. The study was done from July 2015 to June 2017 at NITOR's Department of Orthopedics. Patients with post-traumatic distal patella extra-articular fractures admitted to NITOR comprised the study population. From July 2015 to June 2017, total 52 patients had patellar fractures. At NITOR, 46 people with lower pole patella fractures were wired vertically with surgery. NITOR checked up on 40 people. After 18 weeks, the final functional result was looked at. Bostman knee score measured how the knee worked.
Results: 40 patients with extra-articular distal patella fractures were studied to determine the effectiveness of 2 vertical wirings. 9 (22.5%) of 40 patients were 30 or younger, 10 (25%) were 31-40, and 8 (20%) were 41-50. 7% and 6% of patients were in their 5th and 6th decades. The youngest patient was 18 and the oldest was 70. Out of 40 cases, 31 (or 77.5%) were men and 9 (or 22.5%) were women. The number of men to women is 3.5:1. Most of the 30 broken bones (75%) healed between 6 and 10 weeks. The average time for a radiological union to happen was 82.4 weeks.
Conclusion: According to the study's findings, extra-articular fractures of the distal pole of the patella commonly affect men in early middle age and farmers. Separate vertical wirings cure outside-the-joint distal patella fractures. Most patients can return to their pre-injury activities, but their knees are weaker.
CARACTERIZAÇÃO DE ESTILOS FLUVIAIS NO ALTO E MÉDIO CURSO DA BACIA HIDROGRÁFICA DO PIANCÓ, AMBIENTE SEMIÁRIDO DA PARAÍBA
Authors: Franco Virna Vieira Franco , Lima Vinicius Ferreira Lima , Souza Jonas Otaviano Praça de Souza 
Published: June 2023

A bacia hidrográfica do rio Piancó, inserida em região semiárida no Estado da Paraíba, apresenta questões socioambientais específicas que exigem projetos específicos com relação ao planejamento e gestão ambiental. A pesquisa utiliza a proposta metodológica de Fryirs e Brierley (2000), cujo foco principal é realizar a caracterização de Estilos Fluviais no canal principal da bacia do rio Piancó. A área estudada está delimitada da cabeceira do rio Piancó até a barragem do açude Coremas Mãe-D’água, que vai até o médio curso do rio, no município de Coremas-PB. Desta forma, foram selecionados 4 trechos cuja identificação dos estilos é estabelecida em: trecho 1 Estilo Confinado de Leito Rochoso (ECLR); trecho 2 Estilo Parcialmente Confinado de Leito Arenoso (EPCLA); trecho 3 Estilo Não Confinado de Leito Arenoso com Planície de Inundação Descontínua (ENCLAPID); e trecho 4 Estilo Não Confinado de Leito Arenoso com planície de inundação nas áreas de Extravasamento (ENCLAE).
Biomimetic Diselenide‐Sonosensitizer Nanoplatform for Enhanced Sonodynamic Therapy and In Situ Remodeling Immunosuppressive Microenvironment via Activating Innate and Adaptive Immunotherapy
Authors: Xue Yifan , Wang Qingliang , Chen You , Zhang Xiaoge , Tang Junjie , Liu Yadong , Liu Jie 
Published: January 2025

AbstractSonodynamic therapy (SDT), which is non‐invasive and controllable has the potential to treat triple‐negative breast cancer (TNBC). However, the hypoxia and immunosuppressive tumor microenvironment (TME) often block the production of reactive oxygen species and the induction of SDT‐activated immunogenic cell death, thus limiting the activation of adaptive immune responses. To alleviate these challenges, we proposed the development of a multifunctional biomimetic nanoplatform (mTSeIR), which was designed with diselenide‐conjugated sonosensitizers and tirapazamine (TPZ), encapsulated within M1 macrophage membrane. This nanoplatform utilized hypoxia‐induced chemotherapy to improve the efficacy of SDT, to further enhance adaptive immunotherapy by activating innate immunity and remodeling the immunosuppressive TME. Firstly, the prodrug TPZ was activated due to the increased oxygen consumption associated with SDT. Subsequently, the mTSeIR enhanced repolarization of M2 macrophages to the M1 phenotype. The diselenide component in mTSeIR effectively activated the natural killer cell‐mediated antitumor innate immune response. Ultimately, in vivo studies indicated that mTSeIR+US with good biosafety achieved over 98% tumor inhibition and enhanced adaptive immunotherapy. This research presents an efficient approach that addressed the limitations of SDT and achieves simultaneous activation of both innate and adaptive immunotherapy, resulting in significant antitumor and anti‐metastatic efficacy in TNBC.
Adaptive Robust Formation Tracking Control for Traffic Cone Robots Under Uncertain Disturbances: With Leakage and Dead Zone Types
Authors: Zhang Jiale , Zhang Chuanwei , Jiao Shengjie , Qin Peilin , Wei Meng , Lian Gaoqi 
Published: January 2025

AbstractTraffic cones, as indispensable safety facilities for road maintenance, play a crucial role in directing traffic flow and ensuring construction safety. This study addresses the challenge of adaptive robust formation tracking control for uncertain traffic cone robots (TCRs). Based on the Udwadia–Kalaba method, the kinematic constraints of the TCRs are designed by the artificial potential function. Those constraints are considered as the control objectives realized by robust control. The uncertainty of the TCRs in this study includes matching and mismatching components. To address matching uncertainties, adaptive parameters incorporating dead‐zone and leakage terms are introduced, enabling precise real‐time estimation of uncertainty dynamics. For mismatching uncertainties, a geometric decomposition approach is employed, effectively isolating them in a subspace orthogonal to the formation tracking range space. The proposed system is validated through extensive simulations and real‐world experiments, demonstrating its robustness and practical effectiveness in addressing the stated challenges.
Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA
Authors: Lin Cheng , Kuzmanović Adrian , Wang Nan , Liao Liangliang , Ernst Sabrina , Penners Christian , Jans Alexander , Hammoor Thomas , Stach Petra Bumnuri , Peltzer Mona , Volkert Ines , Zechendorf Elisabeth , Hassan Reham , Myllys Maiju , Liedtke Christian , Herrmann Andreas , Chakraborty Gurudas , Trautwein Christian , Hengstler Jan , Müller‐Newen Gerhard , Wang Junqing , Ghallab Ahmed , Bartneck Matthias 
Published: January 2025

AbstractMost gene therapies exert their actions via manipulation of hepatocytes (parenchymal cells) and the reasons behind the suboptimal performance of synthetic mRNA in non‐parenchymal cells (NPC) such as Kupffer cells (KC), and liver macrophages, remain unclear. Here, the spatio‐temporal distribution of mRNA encoding enhanced green fluorescent protein (Egfp), siRNA, or both co‐encapsulated into lipid nanoparticles (LNP) in the liver in vivo using real‐time intravital imaging is investigated. Although both KC and hepatocytes demonstrate comparable high and rapid uptake of mRNA‐LNP and siRNA‐LNP in vivo, the translation of Egfp mRNA occurs exclusively in hepatocytes during intravital imaging. Despite attempts such as inhibiting intracellular ribonuclease, substituting uridine bases in mRNA with pseudouridine, and using a different ionizable lipid in the LNP mixture, no substantial increase in Egfp translation by NPC is possible. The investigation reveals that hepatocytes, which are distinct from other liver cells due to their polyploidy, exhibit significantly elevated levels of total RNA and protein, along with a higher proportion of ribosomal protein per individual cell. Consequently, fundamental cellular differences account for the low mRNA translation observed in NPC. The findings therefore suggest that cellular biology imposes a natural limitation on synthetic mRNA translation that is strongly influenced by cellular ploidy.
Pheno‐Morphological Screening and Acoustic Sorting of 3D Multicellular Aggregates Using Drop Millifluidics
Authors: Rembotte Leon , Beneyton Thomas , Buisson Lionel , Badon Amaury , Boyreau Adeline , Douillet Camille , Hermant Loic , Jana Anirban , Nassoy Pierre , Baret Jean‐Christophe 
Published: January 2025

AbstractThree‐dimensional multicellular aggregates (MCAs) like organoids and spheroids have become essential tools to study the biological mechanisms involved in the progression of diseases. In cancer research, they are now widely used as in vitro models for drug testing. However, their analysis still relies on tedious manual procedures, which hinders their routine use in large‐scale biological assays. Here, a novel drop millifluidic approach is introduced to screen and sort large populations containing over one thousand MCAs: ImOCAS (Image‐based Organoid Cytometry and Acoustic Sorting). This system utilizes real‐time image processing to detect pheno‐morphological traits in MCAs. They are then encapsulated in millimetric drops, actuated on‐demand using the acoustic radiation force. The performance of ImOCAS is demonstrated by sorting spheroids with uniform sizes from a heterogeneous population, and by isolating organoids from spheroids with different phenotypes. This approach lays the groundwork for high‐throughput screening and high‐content analysis of MCAs with controlled morphological and phenotypical properties, which promises accelerated progress in biomedical research.
A Susceptible Cell‐Selective Delivery (SCSD) of mRNA‐Encoded Cas13d Against Influenza Infection
Authors: Wu Zhuanli , Zhao Chengcheng , Ai Hui , Wang Zhen , Chen Mingyue , Lyu Yanli , Tong Qi , Liu Litao , Sun Honglei , Pu Juan , Zhang Ran , Hu Xiaoxiang , Liu Jinhua , Ma Xiaowei , Sun Yipeng 
Published: January 2025

AbstractTo bolster the capacity for managing potential infectious diseases in the future, it is critical to develop specific antiviral drugs that can be rapidly designed and delivered precisely. Herein, a CRISPR/Cas13d system for broad‐spectrum targeting of influenza A virus (IAV) from human, avian, and swine sources is designed, incorporating Cas13d mRNA and a tandem CRISPR RNA (crRNA) specific for the highly conserved regions of viral polymerase acidic (PA), nucleoprotein (NP), and matrix (M) gene segments, respectively. Given that the virus targets cells with specific receptors but is not limited to a single organ, a Susceptible Cell Selective Delivery (SCSD) system is developed by modifying a lipid nanoparticle with a peptide mimicking the function of the hemagglutinin of influenza virus to target sialic acid receptors. The SCSD system can precisely deliver an all‐RNA‐based CRISPR/Cas13d system into potentially infected cells. This drug is shown to reduce the viral load in the lungs by 2.37 log10 TCID50 mL−1 and protect 100% of mice from lethal influenza infection. The SCSD‐based CRISPR/Cas13d system shows promise for the flexible and efficient therapy of infections caused by rapidly evolving and novel viruses.
Deciphering the Energy Transfer Mechanism Across Metal Halide Perovskite‐Phthalocyanine Interfaces
Authors: Cortés‐Villena Alejandro , Cadranel Alejandro , Azizi Kobra , Torres Tomás , Guldi Dirk M. , Pérez‐Prieto Julia , Galian Raquel E. 
Published: January 2025

AbstractEnergy transfer processes in nanohybrids are at the focal point of conceptualizing, designing, and realizing novel energy‐harvesting systems featuring nanocrystals that absorb photons and transfer their energy unidirectionally to surface‐immobilized functional dyes. Importantly, the functionality of these dyes defines the ultimate application. Herein, CsPbBr3 perovskite nanocrystals (NCs) are interfaced with zinc phthalocyanine (ZnPc) dyes featuring carboxylic acid. The functionality is the photosensitization of singlet oxygen. The CsPbBr3@ZnPc nanohybrid is to the best of our knowledge the first example, in which an unusual Dexter‐type singlet energy transfer between metal halide perovskite nanocrystals and phthalocyanine dyes enables singlet oxygen generation as a proof‐of‐concept application. A detailed temporal picture of the singlet energy transfer mechanism is made possible by combining key time‐resolved spectroscopic techniques, that are, femtosecond, nanosecond, and microsecond transient absorption spectroscopy as well as time‐correlated single photon counting, and target analyses. In fact, three excitonic components in the NCs govern a concerted Dexter‐type energy transfer. The work illustrates the potential of CsPbBr3@ZnPc as a singlet photosensitizer of ZnPc to produce singlet oxygen (1O2) almost quantitatively while photoexciting CsPbBr3.