bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nothing about us without us: A co‐production strategy for communities, researchers and stakeholders to identify ways of improving health and reducing inequalities
Authors: Albert Alexandra , Islam Shahid , Haklay Muki , McEachan Rosemary R. C. 
Published: January 2023

AbstractIntroductionCo‐production with communities is increasingly seen as best practice that can improve the quality, relevance and effectiveness of research and service delivery. Despite this promising position, there remains uncertainty around definitions of co‐production and how to operationalize it. The current paper describes the development of a co‐production strategy to guide the work of the ActEarly multistakeholder preventative research programme to improve children's health in Bradford and Tower Hamlets, UK.MethodsThe strategy used Appreciative Inquiry (AI), an approach following a five‐step iterative process: to define (Step 1) scope and guide progress; to discover (Step 2) key issues through seven focus groups (N = 36) and eight in‐depth interviews with key stakeholders representing community groups, and the voluntary and statutory sectors; to dream (Step 3) best practice through two workshops with AI participants to review findings; to design (Step 4) a co‐production strategy building on AI findings and to deliver (Step 5) the practical guidance in the strategy.ResultsNine principles for how to do co‐production well were identified: power should be shared; embrace a wide range of perspectives and skills; respect and value the lived experience; benefits should be for all involved parties; go to communities and do not expect them to come to you; work flexibly; avoid jargon and ensure availability of the right information; relationships should be built for the long‐term; co‐production activities should be adequately resourced. These principles were based on three underlying values of equality, reciprocity and agency.ConclusionThe empirical insights of the paper highlight the crucial importance of adequate resources and infrastructure to deliver effective co‐production. This documentation of one approach to operationalizing co‐production serves to avert any misappropriations of the term ‘co‐production’ by listening to service users, stakeholders and other relevant groups, to develop trust and long‐term relationships, and build on the learning that already exists amongst such groups.Patient or Public ContributionThe work was overseen by a steering group (N = 17) of individuals, both professional and members of the public with experience in undertaking co‐production, and/or with some knowledge of the context of the two ActEarly field sites, who provided regular oversight and feedback on the AI process.
Maternal exposure to extreme high‐temperature, particulate air pollution and macrosomia in 14 countries of Africa
Authors: Li Guoao , Hu Wenlei , Lu Huanhuan , Liu Jianjun , Li Xue , He Jialiu , Zhu Jinliang , Zhao Huanhuan , Hao Jiahu , Huang Fen 
Published: January 2023

SummaryBackgroundMacrosomia has increased rapidly worldwide in the past few decades, with a huge impact on health. However, the effect of PM2.5and extreme high‐temperature (EHT) on macrosomia has been ignored.ObjectiveThis study aimed to explore the association between maternal exposure to EHT, PM2.5and macrosomia based on the Seventh Demographic and Health Survey (DHS) in 14 countries of Africa.MethodsThe study included detailed demographic information on 106 382 births and maternal. Satellite inversion models estimated monthly mean PM2.5and mean surface temperature of 2 m (SMT2m). Macrosomia was defined as the birth weight ≥ 4000 g. We used a Cox proportional risk regression model to estimate the association between PM2.5, EHT and macrosomia. We further explored the susceptibility of exposure to EHT and PM2.5at different pregnancy periods to macrosomia, and plotted the expose‐response curve between PM2.5and macrosomia risk using a restricted cubic spline function. In addition, the Interplot model was used to investigate the interaction between EHT and PM2.5on macrosomia. Finally, some potential confounding factors were analysed by stratification.ResultsThere was the positive association between EHT, PM2.5and macrosomia, and the risk of macrosomia with the increase in concentrations of PM2.5without clear threshold. Meanwhile, EHT and PM2.5had a higher effect on macrosomia in middle/later and early/middle stages of pregnancy, respectively. There was a significant interaction between EHT and PM2.5on macrosomia.ConclusionsMaternal exposure to EHT, PM2.5during pregnancy was associated with an increased risk of macrosomia in Africa.
Preparation and administration of androgen deprivation therapy products: Retrospective survey results
Authors: Goldfischer Evan R. , Grubb ElizaBeth , Nisbet Paul 
Published: January 2023

AbstractLeuprolide acetate (LA) is a gonadotropin‐releasing hormone agonist used as androgen deprivation therapy for advanced prostate cancer. LA is available in formulations intended for intramuscular (IM‐LA) or subcutaneous (SC‐LA) administration. Post‐marketing reports have noted handling errors associated with the preparation and administration of SC‐LA. This study gathered real‐world evidence on administration and management of IM‐LA and SC‐LA in large, urology‐ or oncology‐based practices. Over 200 staff were invited; 151 participated in an online survey. Main outcomes were time for each step of the ordering, inventory, mixing and administration processes. Mean values and standard errors are reported for continuous variables, and frequency and percentage are reported for categorical variables. Comparisons between groups were made with t tests and chi‐square tests as appropriate. For IM‐LA and SC‐LA, ease of ordering and time to place an order (10.8 ± 1.3 vs. 10.6 ± 1.4 min, respectively) were similar. IM‐LA was associated with a shorter time to complete preparation (2.5 ± 0.2 vs. 6.1 ± 0.6 min, P < 0.001) compared with SC‐LA. This difference of 3.6 min per preparation could result in substantial time savings annually ranging from 120 h per year to 240 h per year in clinical practices administering 2000 injections per year or 4000 injections per year, respectively. For IM‐LA vs. SC‐LA, greater ease of preparation was reported by 64% vs. 43% of respondents, respectively. Over 15% of respondents used injection sites inconsistent with prescribing information, regardless of the type of injection. This study found that it takes a significantly shorter time to prepare and administer IM‐LA than SC‐LA in large urology‐ and oncology‐based practices. The time saved could be utilized for other tasks such as seeing additional patients. Use of injection sites inconsistent with prescribing information suggests a need for more training of nursing staff in the proper administration of these drugs to ensure adequate testosterone suppression and patient safety.
Impact of the COVID‐19 lockdown on the oral health status of paediatric dental patients in Greece
Authors: Angelopoulou Matina V. , Seremidi Kyriaki , Papaioannou William , Gizani Sotiria 
Published: January 2023

AbstractBackgroundLimited evidence regarding the post‐COVID‐19 dental status of paediatric patients is available, with most studies assessing only children's oral health habits.AimTo evaluate the effect of the COVID‐19 lockdown on the oral health of paediatric dental patients in Greece.DesignThis was a retrospective cohort study that included a questionnaire on children's oral health behavior and a clinical examination assessing dental caries and dental treatment needs using the International Caries Detection and Assessment System criteria, dmft/DMFT, and Treatment Need Index. The Wilcoxon signed‐rank test was used for a statistical comparison between questionnaire and clinical data before, during, and after the lockdown.ResultsA total of 102 children with a median age of 9 years were recruited from the current cohort of patients that had their last dental examination 6 months prior to the lockdown. Results from the questionnaire showed decreased brushing frequency with increased eating frequency and sugar consumption during the lockdown period (p < .001). Moreover, 16.5% had to visit the dentist for urgent care during the lockdown, 13.6% experienced dental pain, and 51.5% did not experience any dental emergencies. Clinical examination, after the lockdown, recorded significantly increased mean dmft/DMFT scores by 0.63 units in the primary dentition (p = .01) and 0.52 units in the permanent teeth (p = .002). Significantly higher treatment needs, with more carious lesions requiring extensive treatment after the lockdown, were recorded (p < .001).ConclusionThe COVID‐19 lockdown negatively affected children's oral health behavior: caries prevalence increased and more complex dental treatments were required.
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Authors: Farrell Timothy W. , Volden Tiffany A. , Butler Jorie M. , Eleazer G. Paul , Rupper Randall W. , Echt Katharina V. , Shaughnessy Marianne , Supiano Mark A. 
Published: January 2023

GEC Continuum of Services for Aging Veterans. See the related article by Farrell et al., pages 18–25.
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A Pilot Study of Maternal Songwriting to Support Bonding During Pregnancy: “I Could Feel Her Rise and Fall With My Breath While Singing”
Authors: O'Reilly Gemma , Cheung Pui Sze , McCaffrey Tríona 
Published: January 2023

IntroductionAttachment is a lasting psychological and emotional bond that impacts a child's social, emotional, and cognitive development. Maternal‐fetal attachment is a precursor to this bond that is regarded as a predictor for mother‐infant relating postbirth. Although previous studies have investigated use of music interventions to support maternal‐fetal attachment, no study to date has investigated the use of maternal songwriting to support this bond during pregnancy.MethodsFour pregnant women were recruited to this pilot study. Each woman participated in 2 songwriting workshops with the aim of writing an original song to their fetus. Following the workshops, experiences of using songwriting for the purposes of supporting bonding were investigated through individual semistructured interviews and analyzed using thematic content analysis.ResultsAnalysis of semistructured interviews with pregnant women revealed 3 main themes: song singing promotes physical connection with the fetus; songwriting encourages open communication with the fetus; and songwriting can create a musical legacy within families.DiscussionTo the best of our knowledge, this study is the first of its kind that investigated maternal songwriting to support bonding during pregnancy. Findings indicated that songwriting has the potential to support such attachment due to its capacity to enhance physical connection and open communication with the fetus, while also creating a musical legacy that can be used and passed on among other family members. Overall, songwriting may support pregnant women to draw on their inner resources to create such a bespoke musical gift to their unborn child. Further research around this topic is warranted.
Participation in the CARES Act Provider Relief Fund policy by dentists in South Carolina's safety net
Authors: Marshall Julie L. , Riley Amah , Martin Amy B. 
Published: January 2023

AbstractObjectivesThe Coronavirus Aid, Relief, and Economic Security (CARES) Act appropriated $100 billion to the Provider Relief Fund, allowing for direct payments to health care providers due to COVID‐19. Few studies have evaluated participation in the Provider Relief Fund (PRF), and none have specifically looked at dental providers in the safety net.MethodsWe conducted a retrospective, secondary data analysis using a quasi‐experimental cohort design of South Carolina dentists who received PRF payments, comparing those who did and did not participate in the safety net. Safety net practice was operationalized as those participating in Medicaid, and whether they provided care in dental health professional shortage areas, or rural communities.ResultsOf the 628 dental providers in South Carolina who received PRF payments, 34% were identified as Medicaid providers while 66% did not participate in Medicaid; we found no statistical difference between payments to Medicaid versus non‐Medicaid dental providers. Of PRF payments to dental providers participating in South Carolina's Medicaid program, we found no difference between payments to rural and urban providers but did find that practices offering services in dental care shortage areas received less than providers practicing in counties not designated as a shortage area.ConclusionsThe PRF achieved its goal of distributing financial support to providers affected by the COVID‐19 pandemic. But without policy imperatives linked to need‐based allocations or incentives for PRF recipients to serve safety net populations, we may later learn this was a missed opportunity for PRF.
Chrysosporum ovalisporum is synonymous with the true‐branching cyanobacterium Umezakia natans (Nostocales/Aphanizomenonaceae)
Authors: McGregor Glenn B. , Sendall Barbara C. , Niiyama Yuko , Tuji Akihiro , Willis Anusuya 
Published: January 2023

AbstractTrue branching is a facultative characteristic only known from two cyanobacteria in the Aphanizomenonaceae, Umezakia natans and Dolichospermum brachiatum. In both cases, its expression has been associated with environmental stress, and its practical use as a diacritical feature has been previously evaluated. In this study, we undertook further evaluation of the phylogeny of Umezakia natans and its relationship to Chrysosporum ovalisporum as a previous study suggested the two were potentially congeneric. We used combined morphological, phylogenetic, and phylogenomic approaches to determine their relatedness using new strains available from a broad geographic range. Phylogenetic analysis based on 16S rRNA gene sequences showed that Australian C. ovalisporum and Japanese U. natans strains clustered together with accessions of C. ovalisporum originating from Australia, Israel, and Spain, with high p‐distance similarity values (99.5%–99.9%). Additionally, differences between the two species in the 16S–23S ITS region was low (0%–2.5%). The average nucleotide identity of the U. natans and C. ovalisporum strains was also high (ANI of > 99.5 and AF > 0.9) and supported a genus‐level separation from Chrysosporum bergii (83 ANI between clusters). Furthermore, in culture, strains of both species grown in vitamin‐free media showed facultative true branching, a feature not previously known in C. ovalisporum. Collectively, the results support unification of C. ovalisporum and U. natans according to the principle of priority as Umezakia ovalisporum.
Actor–network theory: A novel approach to supply chain management theory development
Authors: Hald Kim Sundtoft , Spring Martin 
Published: January 2023

AbstractSupply chain management (SCM) researchers often conduct research using theoretical approaches and ontological assumptions adopted from other areas of management. These approaches and assumptions are valid for some aspects of SCM but may also neglect or be unsuited to other questions and concerns that are distinctive to the SCM domain. Actor–network theory (ANT) provides an alternative perspective that addresses some of the blind spots of established approaches. We begin by describing the main theoretical assumptions and the dominant ontological position of ANT, in terms of three principles: relationality, heterogeneity, and performativity. We then show how adopting these principles allows an alternative conceptualization of the supply chain and of SCM itself and discuss the methodological implications of adopting these principles for research in SCM. ANT‐inspired research can make four major contributions to the development of new SCM theory. First, ANT can provide new theoretical insights into the dynamic and fragile character of supply chains, specifically regarding how SCM systems and devices are implemented, constructed, and transformed in practice. Second, ANT can enable the development of SCM theory that leads to a better understanding of how people in SCM roles really act when managing in the supply chain space. Third, the question of what and who manages the supply chain can be explored in radically new ways. Finally, ANT can provide a complementary perspective on power in the supply chain, serving as a good lens for researchers interested in exploring the politics of representing, interpreting, and stabilizing SCM practices and systems.
Demonstration of the discrepancy between AT‐wave morphology on 12‐lead ECG and AT mechanism in scar‐related AT
Authors: Takigawa Masateru , Martin Claire A. , Yamamoto Tasuku , Nakatani Yosuke , Duchateau Josselin , Pambrun Thomas , Derval Nicolas , Sacher Frederic , Hocini Meleze , Nishimura Takuro , Tao Susumu , Miyazaki Shinsuke , Goya Masahiko , Haïssaguerre Michel , Sasano Tetsuo , Jaïs Pierre 
Published: January 2023

AbstractThe 12‐lead electrocardiogram (ECG) is a fundamental modality to help determine the mechanism and the localization of atrial tachycardias (ATs). Although macroreentrant ATs and focal ATs typically show F‐waves and discrete P‐waves respectively on the 12‐lead ECG, this is not universally the case in scar‐related ATs.1, We present three cases clearly showing the discrepancy between the AT morphology on the 12‐lead ECG and the AT‐mechanism.
Electroencephalography signals and neurodevelopment after Kawasaki disease: A pilot study
Authors: Fauteux Audrey‐Ann , Gutierrez Rojas Rocio , Agbogba Kristian , Benovoy Mitchel , Charlebois‐Poirier Audrey‐Rose , Lalancette Eve , Lippé Sarah , Dahdah Nagib 
Published: January 2023

AbstractBackgroundAcute Kawasaki disease (KD) induces central nervous system inflammation and excessive irritability. Long‐term impacts on children's neurodevelopment have only been studied marginally. This pilot study aimed to describe the neuropsychological profile of primary school‐aged children with a history of KD and to explore the impacts of KD on electroencephalography (EEG) markers associated with attention and brain maturation.MethodsFifteen children (8.8 ± 2.5 years) were recruited 4.9 ± 2.7 years after KD onset. Intellectual abilities, long‐term memory, and auditory sustained attention were evaluated. Parents completed standardized questionnaires assessing (1) executive functioning; (2) internalizing and externalizing difficulties; (3) attention deficit hyperactivity disorder symptoms; and (4) autism spectrum disorder symptoms. Theta/beta ratio (TBR) and alpha peak (AP) were extracted from resting‐state EEG and compared with 32 controls (8.9 ± 2.1 years). The alpha band was analyzed using a feature reduction algorithm to detect potential groupings.ResultsPerformances showed preserved intellectual abilities and memory. Sustained attention performance was within the lower range for 4/14 participants (29%), with considerable parental reports of inattention (43%), working memory difficulties (50%), and hyperactivity‐impulsivity (36%). No alterations in the TBR were found but the KD group presented a significantly lower AP amplitude ratio. A clear separation of KD cohort into two clusters showed that acute irritability is associated with a weaker AP.ConclusionsDespite overall preserved cognitive functions, there is a possible association between KD and attention deficit concerns. This first EEG‐based study indicates alpha peak abnormality after KD, predominantly in children with acute irritability. Longitudinal studies are warranted to better characterize patients' neurodevelopmental trajectory.
Expressivism and moral independence
Authors: Salinger Elliot 
Published: January 2023

AbstractMetaethical expressivism faces the perennial objection that its commitment to non‐cognitivism about moral judgment renders the view revisionary of our ordinary moral thought. The standard response to this objection is to say that since the expressivist's theoretical commitments about the nature of moral judgment are independent of normative ethics, the view cannot be revisionary of normative ethics. This essay seeks to evaluate the standard response by exploring several senses of independence that expressivism might enjoy from normative ethics. I develop a taxonomy on which, at least by the expressivist's own lights, normative ethics is not dependent on non‐cognitivism about moral judgment in a way that might render that claim itself normative ethical. The argument will require us to formulate a theory of moral subject matter according to the expressivist, a matter of independent interest. Although this discussion will essentially vindicate the standard response to the perennial objection, it will also highlight a major limitation thereof. This is that even for the expressivist, the taxonomic independence of non‐cognitivism about moral judgment from normative ethics does not guarantee its moral independence from normative ethics; that is, showing that non‐cognitivism about moral judgment is not a moral claim is not itself to show that it is not a morally relevant claim. I conclude by arguing that the question of moral dependence, usually discussed under the heading of objectivity, is ultimately first‐order moral rather than taxonomic, and so can only be resolved on first‐order moral grounds.
Klippel–Fiel syndrome with rare presentation of bilateral temporomandibular joint osteoarthritis – A case report
Authors: Duggal Isha , Pandey Ujjya , Kumar Chaudhari Prabhat , Duggal Ritu 
Published: January 2023

AbstractBackgroundKlippel–Fiel syndrome (KFS) is a rare congenital skeletal disorder characterized clinically by presence of a triad of short neck, limited neck mobility (due to fused cervical vertebrae) and low posterior hair line. It was first described by Maurice Klippel and Andre Feil in 1912. Various skeletal and non‐skeletal anomalies may be seen in association with KFS.Case PresentationThis report aims to highlight orofacial manifestations of a 16‐year‐old male patient with KFS along with a rare presentation of bilateral osteoarthritic changes in the temporomandibular joint. The treatment planning and execution for such a case has also been described.ConclusionBilateral osteoarthritic changes of temporomandibular joint have been rarely reported in KFS. This report emphasizes that early diagnosis of various associated anomalies and timely intervention through an interdisciplinary approach is very essential in the management of patients with KFS.
Real world reduction in red cell transfusion with restrictive transfusion threshold in haematology inpatients
Authors: Pervaiz Omer , Dhanapal Jay , Pillai Lakshmi , Pavord Sue , Leary Heather , Eyre Toby , Peniket Andrew , Staves Julie , Polzella Paolo , Desborough Michael J. R. 
Published: January 2023

AbstractObjectivesThe aim of this study was to assess the reduction in red cell transfusions following a change in the red cell transfusion threshold for haematology inpatients from 80 to 70 g/L.BackgroundHaematology patients are among the high users of red blood cells. We reduced the threshold for transfusion of haematology inpatients to 70 g/L. This was based on evidence provided by randomised controlled trial published in 2020 that showed restrictive transfusion is non‐inferior to liberal transfusion.MethodWe assessed red cell transfusions for haematology inpatients at Oxford University Hospitals NHS Foundation Trust for 9 months before and 9 months after a change in red cell transfusion threshold from 80 to 70 g/L.ResultsAfter the change in threshold to 70 g/L or less from 80 g/L, the median number of red cell transfusions per month reduced to 88 from 111. This was a 23% reduction in the total number of red cells administered per month.ConclusionThese results show the real‐world reductions in transfusion that can be made by putting local transfusion guidelines in line with the international recommendations. This is of particular importance at a time of national blood shortage.