The epidemiological investigation of vitamin D deficiency in northern Henan province
Authors: Deng Huiling , Lin Ziyang , Yang Junzheng 
Published: September 2023

AbstractAim/purposeTo analyze the epidemiology of vitamin D deficiency in northern Henan province, to lay the foundation for prevention and treatment of vitamin D deficiency and the vitamin D related diseases.MethodsWe collected the basic information including gender, age, and vitamin D concentration of 22184 people who detected the 25 hydroxyvitamin D concentration in the Third Affiliated Hospital of Xinxiang Medical University from June 2020 to May 2023, analyzed the vitamin D deficiency distribution in male children population, female children population, male adult population and female adult population; and the differences of 25 hydroxyvitamin D concentration of diabetes mellitus patients in the total investigation population in northern Henan province were also analyzed and compared according to gender, age and different seasons.ResultsA total of 22184 data were collected from June 2020 to May 2023 in the Third Affiliated Hospital of Xinxiang Medical University; the age range of investigation objects was from 1 month to 93 years old; there were 8176 male people and 14008 female people, accounting for 36.86% and 63.14% in the total investigation population, respectively; there were 1318 diabetes mellitus patients, accounting for 5.94% in the total investigation population; there were 796 males and 522 females, accounting for 60.39% and 39.61% in the total 1318 diabetes mellitus patients, respectively; the investigation results demonstrated that the number of people with vitamin deficiency was 278, the number of people with vitamin insufficiency was 1418, and the number of people with normal vitamin concentration was 20488, accounting for 1.25%, 6.39% and 92.35% in the total investigation population, respectively; in the adult female population, the number of people with vitamin deficiency and with vitamin insufficiency were highest compared the male children population, female population and male adult population; the statistical results demonstrated that there were the significantly statistical differences among vitamin D concentration<25nmol/mL population, vitamin D concentration at 25-49 nmol/mL population, and vitamin D concentration at 50∼80 nmol/mL in female adult population at the different age (P=0.0039); and there were no statistical differences in male children population, male adult population and female children population at different ages and at different vitamin D concentrations (P>0.05); the results demonstrated that there were the significantly differences among vitamin D concentration<25nmol/mL population, vitamin D concentration at 25-49 nmol/mL population, and vitamin D concentration at 50∼80 nmol/mL in adult diabetes mellitus population at gender, age and different seasons.92.35% people in northern Henan province had the normal vitamin concentration, there were 7.65% people with vitamin insufficiency or vitamin deficiency in northern Henan province; the number of people with vitamin deficiency and with vitamin insufficiency were highest in the adult female population, and there were the significantly statistical differences in female adult population at the different age at different vitamin concentration population and in diabetes mellitus adult population at gender, age and different seasons.ConclusionThe incidence rate of vitamin insufficiency or vitamin deficiency in northern Henan province was 7.65%, and the epidemiology of vitamin D deficiency in northern Henan province had the specific characteristics. Those evidences may provide useful information for prevention and treatment of vitamin D deficiency and vitamin D related diseases.