bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implications of the COVID-19 vaccine in dental practice of internship dentists at Kafr El-Sheikh University
Authors: Sabry Marwa M. , Elgendy Ahmed AM 
Published: July 2023

Background:
Concerns regarding coronavirus transmission in dentistry practices have been extensively expressed across the world compared with other vocations. Dentistry is the highest at-risk for the severe acute respiratory syndrome coronavirus 2 because of the nature of the dental operations and the dental team's proximity to patients.

Aim
The aim of the study was to assess dental practice of internships dentists at Kafr El-Sheikh University before and after Corona virus (COVID) vaccine availability and to reassess dental practice of them again after providing an educational program about COVID vaccine.

Methods
Two stages: a cohort study (a prospective study) then an interventional study (one group pretest–posttest design). A total of 217 internship dentists were selected by the systematic random technique. All internships' dentists selected in the practice study will be included in the intervention study.

Results
No statistically significant difference in other aspects of dental practice before and after vaccine availability; if practice closed/reduced to urgent procedures only. There was a statistical significance in dentists' perception of the COVID-19 vaccine before and after health educational program intervention.

Conclusion
Despite the fact that the COVID-19 pandemic has had a significant negative impact on dentists and dental practice in Egypt, the COVID vaccine assisted dentists in overcoming the pandemic's long-term effects on their profession's future.
Perception of undergraduate dental students regarding technology-based learning during COVID-19 pandemic
Authors: El Bayoumi Mohamed H. , Mahmoud Hossam M. 
Published: July 2023

Objectives
To assess the satisfaction and attitude of undergraduate dental students in Tanta University Egypt, towards different aspects of technology based (TB) learning during the pandemic outbreak of COVID-19.

Background
COVID-19 pandemic has led governments and institutions to take draconian measures with regards to the ongoing education. In an attempt to balance the safeguarding of students, faculty members, and patients, while keeping education process ongoing, universities were forced to adopt distance education as an alternative to classical face to face education.

Participants and methods
An observational cross-sectional study was carried on 675 undergraduate students of Faculty of Dentistry, Tanta University, Egypt.

Results
The result of the present study revealed that nearly 57% of the participant students expressed positive satisfaction of TB learning and 70% expressed positive attitude. The current work highlighted that satisfaction and positive attitude towards TB learning are positively associated with gender, grade, computer skills and previous experiences of online learning.

Conclusion
Based on the result of the present work, it is clear that improving internet infrastructures, e- learning courses and teaching staff members become a mandatory to face challenges of COVID-19 and similar crises that may happen in the future.
Effect of cements and beverages on ceramics translucency
Authors: Micheal Monica H. , Korsel Amany M. , Hasaneen Fatma A. 
Published: July 2023

Aim
To measure translucency of two ceramic materials with different cements and beverages, and compare them to each other.

Settings and design
In vitro comparative study.

Materials and methods
One hundred twenty ceramic discs (10 mm diameter, 0.5 mm thickness) from IPS e-max press (n = 60) and Celtra press (n = 60), shade A2 LT were assessed. Two cements [Rely X Ultimate resin cement (RC)] and [Nexus resin-modified glass ionomer cement (RMGIC)] applied to ceramic discs with 0.2 mm thickness through custom-made Teflon mold. Specimens were immersed in two beverages (tea and cola) for 4 h/day for 1 week at room temperature. Translucency parameter (TP) of ceramic discs was measured according to CIE L*a*b* system.

Statistical analysis used
One-way analysis of variance and Tukey's post-hoc test.

Results
IPS e-max press showed higher TP values than Celtra press. Discs cemented with RC had higher TP values than those cemented with RMGIC. TP values decreased after immersion in both beverages, with higher TP values to those immersed in cola than those immersed in tea.

Conclusion
IPS e-max press was more translucent than Celtra press A2LT discs. RC resin cement could be used to cement veneers with a high final esthetic outcome.
An Electric‐Magnetic Dual‐Gradient Composite Film Comprising MXene, Hollow Fe3O4, and Bacterial Cellulose for High‐Performance EMI Shielding and Infrared Camouflage
Authors: Liu Mengxin , Zhang Haoran , Huang Xinmeng , Zhang Ziyi , Zhang Kunlai , Chen Zhenwu , Zhou Jintang , Pan Lei 
Published: January 2025

AbstractIt is crucial to develop electromagnetic interference (EMI) shielding materials with high shielding efficiency (SE) and reduced reflection to mitigate the secondary pollution caused by electromagnetic waves (EMWs). Herein, a novel multilayer assembly strategy inspired by the structure of “Turkish dessert—Baklava” is proposed to introduce magnetic hollow Fe3O4 nanospheres (HFO) and conductive MXene nanosheets into a bacterial cellulose (BC) network. Through a layer‐by‐layer vacuum filtration approach, a composite BC/MXene/HFO film with a controllable electric‐magnetic dual‐gradient structure is achieved. The construction of electric‐magnetic dual gradients alleviates the impedance mismatch at the air‐film interface, resulting in reduced reflectivity toward EMWs, while the unique hollow structure of HFO facilitates the “absorption–reflection–reabsorption” process of EMWs. Consequently, the as‐prepared composite film (0.35 mm thickness) exhibits an extraordinary EMI SE of 67.6 dB and a reflection SE as low as 5.1 dB. Furthermore, it also demonstrates exceptional mechanical properties, efficient thermal management, and Joule heating capabilities, as well as remarkable passive and active infrared camouflage performances. This study offers an innovative approach to achieve less reflection and more absorption of EMWs, and expands the application scope of EMI shielding materials in precision electronics, aerospace, and military equipment fields.
Low‐Dimensional Structure Modulation in Ag8SnSe6 for Enhanced Thermoelectric Performance
Authors: Zhao Xueke , Li Mengyao , Jia Mochen , Fiedler Christine , Nan Bingfei , Yang Dongwen , Li Lei , Yuan Zicheng , Song Hongzhang , Liu Yu , Ibáñez Maria , Wang Ziyu , Shan Chongxin , Cabot Andreu 
Published: January 2025

AbstractTernary liquid‐like thermoelectric materials have garnered significant attention due to their ultra‐low lattice thermal conductivity. Among these, Ag8SnSe6 stands out for its exceptionally low sound velocity and thermal conductivity. However, the inherent poor electrical conductivity and suboptimal thermoelectric properties of Ag8SnSe6 necessitate further improvement. Here, a novel approach is initiated to enhance the thermoelectric properties of Ag8SnSe6 by combining low‐dimensionalization with intrinsic doping. For the first time, this work successfully synthesizes single‐phase Ag8SnSe6 nanocrystals, ≈10 nm in size, with the correct phase and composition using a robust and reliable colloidal method. This approach represents a significant improvement over previous reports on this material. Reducing the crystal domains of Ag8SnSe6 to the nanoscale induces quantum confinement effects, increasing the density of states near the Fermi surface. It also introduces additional grain boundaries, which lower the lattice thermal conductivity and simplify structural design. Moreover, incorporating small amounts of Sn nanopowder into the Ag8SnSe6 nanocrystals before consolidation further enhances the thermoelectric performance. Sn acts as a donor dopant, increasing the electronic concentration while at the same time improving their mobility by reducing interface barriers, thus significantly improving the material transport properties. Additionally, the presence of Sn leads to the formation of point defects, dislocations, and secondary phases, which increase phonon scattering and further reduce the thermal conductivity. Through this synergistic optimization, the figure of merit shows a significant increase across a wide temperature range. Overall, a strategy is presented for the controlled preparation of Ag8SnSe6 nanocrystals, the decoupling of their electrical and thermal transport, and the practical application of this material to thermoelectric single‐leg modules.
Tongue Prick Bionic Angularly Adjustable Microneedles for Enhanced Scarless Wound Healing
Authors: Gan Ni , Li Xin , Wei Meng , Li Zhijie , Zhou Shu , Gao Bingbing 
Published: January 2025

AbstractHigh‐tension site wounds are frequently accompanied by challenges associated with hypertrophic scarring. The key to achieving scar‐free healing is the creation of a mechanical environment conducive to scar‐free skin regeneration. Herein, simple rolling punctures are utilized on angle transform molds to develop cat tongue prick bionic angle‐adjustable microneedles (TPMNs) to maintain a firm grip on the periwound skin, thereby reducing tissue tension. The integration of TPMNs with triboelectric nanogenerators (TENGs) enables excellent conductive and triboelectric properties. The system can provide a stable spatial electric field around the wound to promote cell migration. As the microfluid reaches the TPMNs, the self‐driving force is enhanced by a unique angle design to control the microfluid flow rate. Sufficient evidence has shown that TPMNs expedite wound contraction and skin tissue regeneration while concurrently reducing scar formation in mouse trauma model experiments. The innovative TPMNs‐TENGs synergistically provides a highly functional platform for wound tension relief, which is suitable for scar treatment in this study and potentially extends to the construction and regulation of smart wearable devices.
3D Printed Titanium Scaffolds with Bi‐Directional Gradient QK‐Functionalized Surface
Authors: Sun Xiaoyun , Zhong Ru , Wu Congcong , Ye Silin , Yuan Haipeng , Fang Zhou , Chen Junjian , Cheng Delin , Hao Lijing , Chu Lei , Wang Lin 
Published: January 2025

Abstract3D printed titanium scaffold has promising applications in orthopedics. However, the bioinert titanium presents challenges for promoting vascularization and tissue growth within the porous scaffold for stable osteointegration. In this study, a modular porous titanium scaffold is created using 3D printing and a gradient‐surface strategy to immobilize QK peptide on the surface with a bi‐directional gradient distribution. This design featured high peptide density in the interior and low peptide density on both ends, aiming to induce cell migration from ends to interior and subsequently enhance vascularization and osteointegration within the scaffold. In vitro results showed that besides the inherent bioactivity, the gradient distribution of QK positively correlated with endothelial cell migration and promoted angiogenesis. In vivo assay was performed by a segmental bone defect model in rabbit and a spine repair model in sheep. Various staining and Micro‐CT results demonstrated that compared to that with uniformly QK‐functionalized surface, the scaffold with bi‐directional gradient QK‐functionalized surface (Ti‐G) significantly encouraged new tissue growth toward the interior of the scaffold, subsequently facilitated angiogenesis and osteointegration. This study provides an effective strategy for enhancing the bioactivity of peptide‐functionalized scaffolds through the concept of bi‐directional gradients, and holds potential for various 3D printed scaffolds.
Overcoming Energy‐Scaling Barriers: Efficient Ammonia Electrosynthesis on High‐Entropy Alloy Catalysts
Authors: Yin Di , Li Bowen , Gao Boxiang , Chen Mengxue , Chen Dong , Meng You , Zhang Shuai , Zhang Chenxu , Quan Quan , Chen Lijie , Yang Cheng , Wong Chun‐Yuen , Ho Johnny Chung Yin 
Published: January 2025

AbstractElectrochemically converting nitrate (NO3−) to value‐added ammonia (NH3) is a complex process involving an eight‐electron transfer and numerous intermediates, presenting a significant challenge for optimization. A multi‐elemental synergy strategy to regulate the local electronic structure at the atomic level is proposed, creating a broad adsorption energy landscape in high‐entropy alloy (HEA) catalysts. This approach enables optimal adsorption and desorption of various intermediates, effectively overcoming energy‐scaling limitations for efficient NH3 electrosynthesis. The HEA catalyst achieved a high Faradaic efficiency of 94.5 ± 4.3% and a yield rate of 10.2 ± 0.5 mg h−1 mgcat−1. It also demonstrated remarkable stability over 250 h in an integrated three‐chamber device, coupling electrocatalysis with an ammonia recovery unit for continuous NH3 collection. This work elucidates the catalytic mechanisms of multi‐functional HEA systems and offers new perspectives for optimizing multi‐step reactions by circumventing adsorption‐energy scaling limitations.
Iron‐Catalyzed Decarboxylative and Deconstructive Cross‐Coupling of Acrylic Acids with Ketone‐Derived Dihydroquinazolinones
Authors: Lu Xiao‐Yu , Su Meng‐Xue , Huang Hua‐Yi , Qian Yu‐Jun , Sun Hai‐Lun , Li Xiang , Hu Xin‐Ru , Dong Hao‐Yu 
Published: January 2025

AbstractHerein, an iron‐catalyzed protocol for the aromatization‐driven deconstruction and decarboxylation of ketone‐derived dihydroquinazolinones in reaction with unsaturated carboxylic acids is reported. A diverse range of fluoroacrylic acids and cinnamic acids reacted effectively with dihydroquinazolinones, yielding essential monofluoroalkenes and alkenes with excellent stereoselectivity. Additionally, spiro‐dihydroquinazolinones served as suitable substrates, facilitating the synthesis of valuable quinazolin‐4(3H)‐ones featuring alkene motifs. This protocol is notable for its operational simplicity and versatility, enabling the chemical diversification of active molecules.
SMAD4 Pathogenic Variants in Seven New Brazilian Individuals With Myhre Syndrome Including a New Family
Authors: Spineli‐Silva Samira , Pontes Larissa Bretanha , de Leeuw Nicole , Correia‐Costa Gabriela Roldão , de Wallau Melissa Bittencourt , Versiani Beatriz Ribeiro , Mazzeu Juliana Forte , Boy Raquel , Gil‐da‐Silva‐Lopes Vera Lúcia , Vieira Társis Paiva 
Published: January 2025

ABSTRACTMyhre syndrome is a rare disorder caused by pathogenic gain‐of‐function variants in the SMAD4 gene. Most of the patients have had de novo variants. There are several instances of autosomal dominant inheritance, and penetrance appears to be complete. We describe seven Brazilian patients, three of whom are siblings carrying the recurrent c.1486C>T p.(Arg496Cys) variant in SMAD4 inherited from the father. The other three patients are unrelated simplex cases. All affected individuals have clinical features commonly found in Myhre syndrome, including typical dysmorphic facial features, with intra‐ and interfamilial clinical heterogeneity. Five of the patients have developmental delay and/or clinical signs of intellectual disability. However, only one had neuropsychological testing. Only one patient had a diagnosis of autism spectrum disorder. As in previously reported families, this new family has the same c.1486C>T p.(Arg496Cys) variant. This is the first study describing Brazilian patients with Myhre syndrome, highlighting the clinical variability of this rare disease. We reinforce the need to investigate the parents to provide appropriate genetic counseling.
Dendritic Platinum Nanoparticles Shielded by Pt‐S PEGylation as Intracellular Reactors for Bioorthogonal Uncaging Chemistry
Authors: Garcia‐Peiro Jose I. , Ortega‐Liebana M. Carmen , Adam Catherine , Lorente‐Macías Álvaro , Travnickova Jana , Patton E. Elizabeth , Guerrero‐López Paula , Garcia‐Aznar J. Manuel , Hueso Jose L. , Santamaria Jesus , Unciti‐Broceta Asier 
Published: January 2025

AbstractBeyond their classical role as cytotoxics, Platinum (Pt) coordination complexes recently joined the selected group of transition metals capable of performing bioorthogonal reactions in living environments. To minimize their reactivity towards nucleophiles, which limit their catalytic performance, we investigated the use of Pt(0) with different forms, sizes and surface functionalization. We report herein the development of PEGylated Pt nanodendrites with the capacity to activate prodyes and prodrugs in cell culture and in vivo. Their dendritic morphology together with their surface shielding through Pt−S‐bonded PEGylation synergistically contributed to create catalytic nanoreactors compatible with the highly‐crowded and reductive environment of the cell cytoplasm, thereby facilitating in situ bioorthogonal drug uncaging in cancer cells in 2D and 3D culture, including in microfluidic systems, and xenografted in zebrafish.
High protein sunflower‐based edible coating to preserve roasted sunflower seeds
Authors: Valentinuzzi María Cecilia , Camiletti Ornella Francina , Grosso Nelson Rubén 
Published: January 2025

AbstractThe application of edible coatings allows the shelf life of food products to be extended, since they provide physical resistance, reduce the moisture exchange of the product, and also reduce oxygen permeability, avoiding chemical changes such as nutrient oxidation. The objective of this study was to develop an edible coating made from sunflower protein flour and apply it to roasted sunflower seeds as a preservation procedure for this food product. Roasted sunflower seeds were prepared with and without sunflower coating and stored for 60 days at room temperature. Samples were extracted every 15 days to determine the peroxide values (PV), conjugated dienes (CD) and volatile compounds. The uncoated seeds showed the highest PV (83.7 mEqO2/kg at Day 15 and 149.2 mEqO2/kg at Day 60), while the coated seeds presented lower values (39.2 and 69.3 mEqO2/kg at 15 and 60 days, respectively). Regarding the DC values, this parameter also showed the same behavior as PV. Thirteen volatile compounds were identified in analyzed samples (by GC–MS), where hexanal, 2‐octenal and nonanal showed significant variations. The uncoated sunflower seeds showed a greater release of volatile compounds. According to the correlation analysis, hexanal presented the highest correlation value between CD and PV in coated (0.76 and 0.79, respectively) and uncoated seeds (0.70 and 0.91, respectively). The obtained results suggest that, although the oxidative reactions occur in roasted sunflower seeds, the application of the coating delays this deterioration process, slows down the oxidation of lipids and contributes to prolonging the useful life of this product.
Manganese Peroxidase Participates in the Liquid–Solid–Gas Triphase Regulation on Microbial Degradation of Lignocellulose in Solid‐State Fermentation
Authors: Zhu Lei , Ding Juan , Xue Wenjing , Zhou Shu , Wang Longyu , Jiang Ailiang , Zhao Mingwen , He Qin , Ren Ang 
Published: January 2025

ABSTRACTThe three‐phase structure of solid‐state fermentation (SSF) directly affects substrate degradation and fermentation efficiency. However, the mechanism of three‐phase regulation on lignocellulose utilization and microbial metabolism is still unclear. Based on comparative transcriptome analysis, a lignocellulose degrading enzyme, manganese peroxidase (GlMnP), which was significantly affected by water stress meanwhile related to triphase utilization, was screened to reveal the mechanism using Ganoderma lucidum as the reference strain. The results showed that GlMnP directly participates in lignocellulose degradation by positively regulating the activity of carboxymethylcellulase (CMCase), filter paper (FPAse), and laccase (LACase) enzymes, and indirectly participates in lignocellulose degradation by negatively regulating the redox levels in microorganisms. In addition, GlMnP can also control microbial glycolysis rate to enhance lignocellulose utilization. The results indicated that GlMnP participates in the liquid–solid–gas triphase regulation on lignocellulose degradation by G. lucidum in SSF.
Impact of Financial Toxicity on the Health‐Related Quality of Life and Financial Well‐Being of Cancer Patients and Survivors: A Comparative Study of the United Kingdom and United States
Authors: Ngan Tran Thu , Tonorezos Emily , Donnelly Michael , O'Neill Ciaran 
Published: January 2025

ABSTRACTBackgroundThis study investigated and compared the impact of financial toxicity (FT) on the health‐related quality of life (HRQoL) and financial well‐being of cancer patients and survivors in the United Kingdom (UK) and United States (US).MethodsUK & US participants (n = 600) completed an online questionnaire that consisted of a validated FT instrument (COmprehensive Score for financial Toxicity‐COST), a standardised HRQoL instrument (EQ‐5D‐5L) and questions related to their financial well‐being. Tobit regression models and descriptive statistics plus χ2 tests were used to analyse the association between FT and (i) HRQoL whilst controlling for sociodemographic characteristics; and (ii) financial well‐being.ResultsIn the UK, health utilities of participants with no assessed experience of FT, mild FT, and moderate/severe FT were 0.81, 0.66, and 0.41, respectively, compared to 0.88, 0.71, and 0.53 in the US. Among those with moderate/severe FT, US participants had significantly higher health utilities compared to their peers in the UK (Mann Whitney test, p = 0.0369). In a pooled analysis of UK and US and after controlling for sociodemographic and clinical characteristics, mild and moderate/severe FT was negatively associated with health utilities (β coff = −0.13, 95% CI: −0.18, −0.08 and β coff = −0.28, 95% CI: −0.34, −0.21, respectively). Over half (54%) of US participants with FT were in debt with median (IQR) debt at I$11,500 (23,000), compared to 32% in the UK with median (IQR) debt at I$ 7200 (12,960). US participants with FT were 2.48 times more likely to be in debt than UK participants with FT (OR = 2.48, 95% CI: 1.46–4.21).ConclusionsFT is associated with poorer financial well‐being and HRQoL among cancer patients/survivors in the US and UK. The impact of FT on financial well‐being is larger in the US while the impact on HRQoL is worse in the UK. Further studies using prospective data are required to investigate the nature and extent of these relationships.
‘Why Don't We Get Counselling?’: Comparing NICE Guidelines for Morphological and Genetic Cancer Risk Diagnoses
Authors: Davies Elspeth 
Published: January 2025

ABSTRACTBackgroundIn the UK's National Health Service (NHS), there is specific psychosocial care offered to people with genetic cancer risk conditions but not morphological cancer risk conditions. As researchers develop new ways to diagnose morphological risk conditions, including precancers and in situ cancers, it is important to consider the psychosocial care that those diagnosed might require.ObjectivesThis study compares the National Institute for Health and Care Excellence's guidelines for BRCA1/2, which are genetic risk conditions, and Barrett's oesophagus (BO), a morphological risk condition. It then theorises reasons for the similarities and differences made visible by this comparative work.MethodsThe author completed an in‐depth analysis of two sets of NICE guidelines, before carrying out a review of historical and social scientific literature on cancer risk to offer potential explanations for the disparities identified.ResultsThe ‘right not to know’ is protected in the case of BRCA1/2 diagnoses, but not BO. Additionally, specialist counselling is required for people receiving diagnoses of genetic risk but not offered for those diagnosed with morphological risk conditions. The paper offers four possible reasons for these disparities, concluding that they appear to be in large part due to historic genetic exceptionalism, rather than differences in patients' needs.ConclusionThere may be a need to consider offering further psychosocial care to people with morphological risk conditions like BO. Lessons might be learnt from the field of genetic counselling.