bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishment and Application of Cricothyrotomy In Vivo
Authors: SONG Fengxiang , HAN Cailing , QIU Yuxue , HOU Haitao , YAN Xiaoqiong , DENG Liqin 
Published: January 2023

Abstract
Background:
Cricothyrotomy is a procedure performed to establish an airway in critical airway events. It is performed only rarely and anesthesiologists are often unprepared when called upon to perform it. This study aimed to simulate cricothyrotomy using pig larynx and trachea models to help anesthesiologists master cricothyrotomy and improve the ability to establish cricothyrotomy quickly.
Methods:
The porcine larynx and trachea were dissected and covered with pigskin to simulate the structure of the anterior neck of a human patient. An animal model of cricothyrotomy was established. Forty anesthesiologists were randomly divided into four groups. Each physician performed three rounds of cricothyrotomy, and recorded the time to accomplish each successful operation. The satisfaction and application value of all physicians with this animal model were evaluated using percentage scores.
Results:
Through repeated practice, compared with the time spent in the first round of the operation (60 ± 17 seconds), the time spent in the second round of the operation (44 ± 14 seconds) and the time spent in the third round of the operation (36 ± 11 seconds) were significantly shortened (P < 0.05). Finally, 95% of all physicians were very satisfied with this animal model, and 5% were relatively satisfied. In addition, 95% of all physicians rated the application value of this animal model as excellent, and 5% rated it as good.
Conclusion:
The porcine larynx and trachea model is an excellent animal model for simulating and practicing cricothyrotomy, helping anesthesiologists to master cricothyrotomy and to perform it proficiently when required.
Risk Factors Associated with Poor Adherence to Blood Pressure Monitoring in Postpartum Discharged Patients with Hypertensive Disorders of Pregnancy
Authors: Li Jingjing. , Zhou Qin , Wang Yixuan. , Duan Lufen , Xu Guangjuan , Zhu Liping. , Zhou Liping. , Peng Lan. , Tang Lian. , Yu Yanxia. 
Published: January 2023

Abstract
Background
This study aims to investigate the risk factors for poor adherence to BP monitoring within 3 months after discharge from the hospital in postpartum discharged HDP patients. Likewise, females with hypertensive disorders of pregnancy (HDP) in China should have a blood pressure (BP) evaluation continuously for at least 42 days postpartum and have BP, urine routine, and lipid and glucose screening for 3 months postpartum.
Methods
This study is a prospective cohort study of postpartum discharged HDP patients. After telephone follow-up was conducted at 1 week, 6 weeks, and 12 weeks after discharge, the maternal demographic characteristics, labor and delivery details, laboratory test results of patients at admission, and adherence to BP monitoring after discharge were collected. While logistic regression analysis was used to analyze the factors related to poor adherence to BP monitoring, the receiver operating characteristic (ROC) curve was drawn to evaluate the model’s predictive value for the poor adherence to BP monitoring.
Results
In this study, 272 females met the inclusion criteria, and poor adherence to BP monitoring was presented in 182 patients (66.9%). A multivariate logistic regression analysis identified the education level of high school or below (OR 2.787, 95% CI 1.452–5.351), parity (OR 1.622, 95% CI 1.007–2.612), and delivery gestational age (OR 1.254, 95% CI 1.053–1.493) as independent risk factors in predicting a poor adherence to BP monitoring. The ROC curve analysis indicated that the continuous variable delivery gestational age had a significant predictive value for the poor adherence to BP monitoring, which resulted in a cutoff point of 33.4 weeks. Parity had a limited predictive value, with a cutoff point of 2. The established prediction regression model combined education level, parity and delivery gestational age had the maximal area under the curve (AUC, AUC = 0.746) and better sensitivity (66.5%) and specificity (71.1%).
Conclusion
Poor adherence to BP monitoring is a common state in postpartum HDP patients after discharge. Females with an education level of high school or below, a parity of two or more, and delivered at gestational age ≥ 33.4 weeks were unlikely to adhere to BP monitoring after discharge.
Non-Accidental Trauma Screening in a Pediatric ED; Does TRAIN(ing) Help?
Authors: Heyming Theodore , Knudsen-Robbins Chloe , Sharma Supriya , Thackeray Jonathan , Schomberg John , Lara Bryan , Wickens Maxwell , Wong Daphne 
Published: January 2023

Abstract
Background
Child maltreatment is distressingly prevalent yet remains under-recognized by healthcare providers. In 2015 the Ohio Children's Hospital Association developed the Timely Recognition of Abusive INjuries (TRAIN) collaborative in an effort to promote non-accidental trauma (NAT) screening. Our institution implemented the TRAIN initiative in 2019. The objective of this study was to examine the effects of the TRAIN initiative at this institution.
Methods
In this retrospective chart review we recorded the incidence of sentinel injuries (SIS) in children presenting to the Emergency Department (ED) of an independent level 2 pediatric trauma center. SIS were defined and identified by a diagnosis of ecchymosis, contusion, fracture, head injury, intracranial hemorrhage, abdominal trauma, open wound, laceration, abrasion, oropharyngeal injury, genital injury, intoxication, or burn in a child < 6.01 months of age. Patients were stratified into pre-TRAIN (PRE), 1/2017-9/2018, or post-TRAIN (POST), 10/2019-7/2020, periods. Repeat injury was defined as a subsequent visit for any of the previously mentioned diagnoses within 12 months of the initial visit. Demographics/visit characteristics were analyzed using Chi square analysis, Fischer’s exact test, and student’s paired t-test.
Results
In the PRE period, 12,812 ED visits were made by children < 6.01 months old; 2.8% of these visits were made by patients with SIS. In the POST period there were 5,372 ED visits, 2.6% involved SIS (p = .4). The rate of skeletal surveys performed on patients with SIS increased from 17.1% in the PRE period to 27.2% in the POST period (p = .01). The positivity rate of skeletal surveys in the PRE versus POST period was 18.9% and 26.3% respectively (p = .45). Repeat injury rates did not differ significantly in patients with SIS pre- versus post-TRAIN (p = .44).
Conclusion
Implementation of TRAIN at this institution appears to be associated with increased skeletal survey rates, suggestive of improved NAT evaluation.
Paclobutrazol suppresses the synthesis of key secondary metabolites by antagonizing gibberellin signaling in Pseudostellaria heterophylla
Authors: Xiao Chenghong , Zhang Jinqiang , Zhang Chen , Ouyang Zhen , Wu Taosheng , Yang Changgui , Yuan Qingsong , Xu Jiao , Li Liangyuan , Zhou Tao 
Published: January 2023

Abstract
Background：Pseudostellaria heterophyllais one of the most well-known traditional Chinese medicines, and its secondary metabolites play an important medicinal role. Paclobutrazol (PBZ), an antagonist of the plant hormone gibberellin, is widely used to increase the yield of P. heterophylla. Whether PBZ affects the synthesis and accumulation of the plant’s secondary metabolites is unclear. Here we investigated the effects of PBZ on the production of polysaccharides, saponins and heterophyllin B in the root tubers of P. heterophylla, and further explored its molecular mechanisms.
Results：We found that PBZ promoted the yield of P. heterophylla, but reduced the accumulation of polysaccharides, saponins and heterophyllin B. PBZ dramatically downregulated genes associated with gibberellin synthesis and reduced concentration of the hormone in root tubers. Inhibition of gibberellin signaling by PBZ altered the expression of genes involved in synthesis and metabolism of polysaccharides, saponins and heterophyllin B.Exogenous gibberellin reversed these effects.
Conclusion：These results suggest that PBZ suppresses the synthesis of saponins, polysaccharides and heterophyllin B by antagonizing gibberellin signaling in P. heterophylla, providing important guidance for its cultivation.
Restoration of Intrinsic Hand Function By Superficial Radial Nerve: An Anatomical Study
Authors: Liang Shuo , Liu Yu-Zhou , Hu Xiao-Qian , Zhao Xin , Lao Jie 
Published: January 2023

Abstract
Background:Contralateral seventh cervical(cC7) nerve root transfer is one of the most important techniques for treating total brachial plexus avulsion injury. The traditional cC7 uses the whole ulnar nerve as a graft, which sacrifices the restorative potential of the ulnar nerve.
Objective: This innovative cadaveric study aims to evaluate the possibility and feasibility of modified cC7 that preserve the motor branch of the ulnar nerve(MBUN), after cC7, using recovered superficial radial nerve(SRN) to repair.
Methods: Ten adult cadavers provided by the Anatomy, Histology, and Embryology Department of Fudan University, China were dissected to evaluate the feasibility of this technique. In this study, only the dorsal and superficial branches of the ulnar nerve and SRN were harvested to connect the cC7 nerve and the recipient nerves. Both the median nerve and MBUN were the recipient nerves. To evaluate the feasibility, the SRN, as well as the motor and sensory branches of the ulnar nerve were dissected. The distances from the reverse point of SRN to wrist flexion crease, as well as to the coaptation point of SRN and MBUN were measured. The MBUN was dissected from distal to proximal and the maximum length was measured. The diameter of nerve branches and the number of axons were evaluated.
Results:This modified approach was technically feasible in all limbs. The distances from the reverse point of SRN to wrist flexion crease was 8.20±1.72cm, and that to the coaptation point was 6.63±1.67cm. The maximum length of the MBUN was 7.44±1.16cm. The mean diameters of axons of the MBUN and SRN distal lateral and medial branches were 1.85±0.41mm、1.99±0.45mm and 1.57±0.37mm, respectively. The corresponding mean numbers of axons were 1401±140 and 742 ±73、712 ±59, respectively.
Conclusion: The SRN could be transferred to the MBUN without a nerve graft. The possible advantage of this modification was that the potential of MBUN was preserved.
Understanding Integrated Hpv Testing and Treatment of Pre- Cancerous Cervical Cancer in Burkina Faso, Cote D’Ivoire, Guatemala and Philippines: Study Protocol
Authors: Kabue Mark , Gauvreau Cindy L. , Daceney Nemdia , Bertram Margaret Mary , Shissler Tracey , Reis Veronica , Dodo Mathurin , Garces Ana , Llave Cecilia , Dao Blami , Huang Lisa 
Published: January 2023

Abstract
Background
Many low- and-middle-income countries are disproportionately burdened by cervical cancer, resulting in high morbidity and mortality. HPV-DNA testing couple with treatment with thermal ablation is a recommended screening and precancer treatment strategy, but not enough is known about how this can be effectively implemented in the context of integrated services. The (Scale Up Cervical Cancer Elimination by Secondary prevention Strategy, (SUCCESS) project is conducting a study to understand this approach, integrated into existing women’s health services in Burkina Faso, Cote d’Ivoire, Guatemala, and the Philippines.
Methods
A hybrid effectiveness-implementation type III mixed-methods observational study design is used to assess feasibility, acceptability, and costs of integrated service delivery in 10 sites per country, selected considering urban/rural location, facility level, onsite/offsite laboratories, and health services type. A combined sample size of about 8,000 women aged 25–49 years was computed, 15% being HIV positive, thus about 2000 per country. The primary outcome is proportion of HPV positive women completing precancer treatment, if eligible, within three months of screening. Data collection and analysis includes; facility and client exit surveys, key informant and client interviews, registries and project records extractions, and costing data analysis. Analysis includes descriptive statistics, context description, thematic analysis, and document analysis. Quantitative analyses will be stratified by participant’s HIV status.
Discussion
Recruitment is ongoing; started in April 2022 (Burkina Faso and Côte d’Ivoire) and August 2022 (Guatemala and the Philippines). Follow-up of study participants 12-months post-treatment is expected to be completed for all countries by April 2024. In LMICs, integrating cervical cancer secondary prevention services into other health services will likely require specific rather than incidental recruitment of women for screening. Reconfiguration of laboratory infrastructure and planning for sample management must be made well in advance to meet induced demand for screening.
Registration:
ClinicalTrials.Gov ID: NCT05133661 (24/11/2021)
Improvement of oral health knowledge and behavior of diabetic patients: An interventional study by using the social media
Authors: Haghdoost Atousa , Bakhshandeh Soheila , Tohidi Sajjad , Ghorbani Zahra , Namdari Mahshid 
Published: January 2023

Abstract
Background: Diabetic patients are not often aware of the relationship between diabetes mellitus (DM) and periodontal diseases, and researchers recommend further knowledge enhancement of diabetic patients in this regard. This study aimed to enhance the oral health knowledge of diabetic adults through an educational intervention.
Methods: In this interventional study, three private offices of endocrinologists specialized in treatment of DM were selected for recruitment of the participants. Totally, 120 diabetic adults (40 from each office) participated in an educational intervention in three groups (patients from each office comprised one group): (I) physician-aid (receiving an educational brochure and CD from their endocrinologist), (II) researcher-aid (receiving an educational brochure and CD from the researcher), and (III) social media (joining an educational group in WhatsApp for 3 months). A self-reported standard questionnaire was filled out by patients before and after the intervention to assess oral health knowledge. Data were analyzed by SPSS version 21 using independent t-test, Mann-Whitney test, Chi-square test, and ANCOVA.
Results: The mean oral health knowledge score increased in all three groups after the educational interventions (P<0.001); the highest increase occurred in the social media group. Toothbrushing twice daily or more had the greatest improvement in physician-aid group compared with the other two groups (P<0.001). The greatest improvement in dental flossing once daily or more occurred in the social media group (P=0.01). The mean level of the hemoglobin A1c (HbA1c) decreased in all three groups but not significantly (P=0.83).
Conclusion: The results revealed that educational interventions enhance the oral health knowledge and improve the behavior of diabetic adults. Education through the social media can be an efficient method for knowledge enhancement of diabetic patients.
Validation of CYGNSS soil moisture products using in-situ measurments: A case study of Southern China
Authors: Dong Zhounan , Jin Shuanggen , Li Li , Wang Peng 
Published: January 2023

Abstract
In terrestrial remote sensing applications, the spaceborne Global Navigation Satellite System-Reflectometry (GNSS-R) has demonstrated its worth. The application to land surface soil moisture (SSM) detection is particularly intriguing since it has the ability to provide fine-scale results to supplement traditional satellite-based active and passive missions. To date, many retrieval algorithms for spaceborne GNSS-R have been developed in order to produce SSM products. However, detailed product reliability and robustness evaluations are still absent. In this study, the satellite-based microwave radiometry product, the model-base product, and in-situ measurements from the Chinese soil moisture monitoring network with over 1800 ground stations during the year 2018 were used to evaluate the CYclone Global Navigation Satellite System (CYGNSS) mission Level-3 SSM products released by the University Corporation for Atmospheric Research (UCAR) and the University of Colorado at Boulder (CU). Typical relative skill metrics and triple collocation-based metrics, along with corresponding confidence intervals, are given to analyze the performance. According to the pixel-by-pixel validation and overall statistical findings, the results reveal that the current CYGNSS-based SSM exhibits low performance in southern China when compared to the radiometry-based data with a low R2 (median R2=0.09) and the ubRMSD 0.055 cm3cm-3, which is poorer than the results from SMAP against in-situ measurements (median R2=0.25, ubRMSD=0.046 cm3cm-3). To acquire better results to support the related operational applications in the future, the new enhanced retrieval algorithms and high-accuracy calibration referenced data must be used.
Risk Factors and Attitudes towards Osteoporosis among the Palestinian Females in Occupied Palestinian Territories
Authors: Natour Nihal , alshawish Eman , Tell Mariam A 
Published: January 2023

Abstract
Introduction:
Osteoporosis is a leading cause of fracture associated mortality and morbidity and its prevention is important for Palestinian society.
Methods:
A structured questionnaire was distributed to females in Palestinian territories about risk factors for osteoporosis and attitudes towards the diseases. Data was analyzed using SPSS.
Results:
92 women participated in this study, among studied women only 7 were postmenopausal, Age was 30.8±12.3 y, BMI is 25.1± 6.6 Kg/m2, attitude score was 5.75±1.6. 58% had bachelors degree, 44% were teachers, 23.5% were health workers. 65.9% lived in separate houses. Having job was associated with lower attitude towards importance (0.04) of osteoporosis but improved dairy products consumption. The rate of consuming dairy product on regular basis was higher than 50% , but there was high rate of vitamin D deficiency (37%) and low level of physical activity performance (18%).
Conclusion:
There is high prevalence for osteoporosis risk factors, but high rate of using dairy products, and modest attitude towards importance of osteoporosis
Implantation of Ascyrus Medical Dissection Stent, Our First-Hand Experience
Authors: Kanj Mohammad , Cosset Benoit , Oliny Alexandre , Farhat Fadi 
Published: January 2023

Abstract
Background
Acute type A aortic dissection is associated with high perioperative amorbidity and mortality. Ascyrus Medical Dissection Stent is a novel uncovered hybrid stent graft developed to be used as an adjunct to standard surgical approach to promote true lumen expansion and enhance aortic remodeling.
Methods
From March 2021 to March 2022, four consecutive patients presented with acute Debakey type I aortic dissection and underwent emergent surgical repair with David procedure and implantation of AMDS. We reviewed patient’s files retrospectively and described the perioperative outcomes.
Results
All four device implantations were successful. Overall 30-day mortality was 0%. Malperfusion that was present in two patients pre-operatively improved after AMDS implantation. No aortic reinterventions were needed. No aortic injury related to the device was noted. Favourable changes in aortic true lumen and false lumen dimensions were found in most of our patients but the AMDS was compressed at the isthmus in one patient.
Conclusion
AMDS is a reliable and secure device. However, its benefits remain unclear when it comes to a positive remodeling and seems less likelihood comparable to a frozen elephant trunk. The main reason seems to be an insufficient radial force of the AMDS.
Glaciers and postglacial ecosystems: common goods to protect in the Anthropocene
Authors: Bosson Jean-Baptiste , Huss Matthias , Cauvy-Fraunié Sophie , Clément Jean-Christophe , Costes Guillaume , Fischer Mauro , Poulenard Jérôme , Arthaud Florent 
Published: January 2023

Abstract
Glacier shrinking and the development of postglacial ecosystems related to anthropogenic climate change is one of the fastest ongoing ecosystem shifts, with paramount ecological and societal cascading consequences globally (Huss et al., 2017; Milner et al., 2017; Cauvy and Dangles, 2019; IPCC, 2021). Yet, no complete spatial analysis exists to quantify or anticipate this major changeover (Ficetola et al., 2021; Zimmer et al., 2022). Here we model glacier responses to climate projections until 2100 and subglacial terrain to explore the ecological trajectory of all glaciated areas, outside the Antarctica and Greenland ice sheets. Depending on climate change magnitude, glaciers could lose less than one quarter to half of their area by 2100. Mainly composed of terrestrial, then marine and freshwater areas, deglaciated areas could range from the equivalent surface of Nepal to Finland. Ecological conditions in deglaciated areas will remain extreme in some regions, offering refuges for cold-adapted species, but become mild in others, favouring biogeochemical processes, primary productivity and generalist species. This unprecedented travel into the future of cold regions shows that glaciers and postglacial ecosystems have key roles to play to face climate change, biodiversity loss and freshwater scarcity. Less than a third of these vulnerable common goods, barely considered in nature conservation policies (IPBES, 2019), are located within protected areas. We therefore call to urgently enhance both climate change mitigation and the in-situ protection of these key ecosystems to secure their existence, functioning and values.
Evaluating the effectiveness of Chlorhexidine on Gram-positive and Gram-negative bacteria in Iran: a systematic review
Authors: Abniki Reza , Masoudi Melika , Tashakor Amirhosein , Mansury Davood 
Published: January 2023

Abstract
Objective(s): Chlorhexidine is a highly effective, broad-spectrum antimicrobial agent available as a mouthwash, gel, spray, root canal rinse, and periodontal chips. Different results of the effectiveness of this substance have been reported in the studies, hence the aim of this survey is a systematic review of the studies conducted on the minimum inhibitory concentration(MIC) of chlorhexidine on Gram-positive and Gram-negative bacteria isolated in health care centers in Iran.
Materials and Methods: The data of this systemic review study were searched from international database including EMBASE, Scopus, PubMed/Medline and Cochrane library using appropriate English keywords until October 2022 and after filtering based on inclusion and exclusion criteria, 12 articles entered our study.
Results: Out of a total 12 articles, 7 studies were conducted on Gram-positive bacteria,4 studies were conducted on Gram-negative bacteria and 1 study was assessed on both groups. Most studies have been done on Staphylococcus aureus and Pseudomonas aeruginosa. The lowest and admissible MIC was 0.5 µg/mL and on the flip side the highest was 625 µg/mL.
Conclusion: Based on our analysis, antibacterial activity of chlorhexidine against Gram-negative and positive bacteria was discouraging. However, further clinical studies are necessitated to provide clinical evidence to support these observations.