bluuebunny/crossref_metadata_2025_split huggingface dataset:
The bisphosphonates alendronate and zoledronate induce adaptations of aerobic metabolism in permanent human endothelial cells
Authors: Budzinska Adrianna , Galganski Lukasz , Jarmuszkiewicz Wieslawa 
Published: September 2023

AbstractNitrogen-containing bisphosphonates (NBPs), compounds that are widely used in the treatment of bone disorders, may cause side effects related to endothelial dysfunction. The aim of our study was to investigate the effects of chronic 6-day exposure to two common bone-preserving drugs, alendronate and zoledronate, on endothelial function and oxidative metabolism of cultured human endothelial cells (EA.hy926). NBPs reduced cell viability, induced oxidative stress and a pro-inflammatory state and downregulated the prenylation-dependent ERK1/2 signaling pathway in endothelial cells. In addition, NBPs induced increased anaerobic respiration and slightly increased oxidative mitochondrial capacity, affecting mitochondrial turnover through reduced mitochondrial fission. Moreover, by blocking the mevalonate pathway, NBPs caused a significant decrease in the level of coenzyme Q10, thereby depriving endothelial cells of an important antioxidant and mitochondrial electron carrier. This resulted in increased formation of reactive oxygen species (ROS), upregulation of antioxidant enzymes, and impairment of mitochondrial respiratory function. A general decrease in mitochondrial respiration occurred with stronger reducing fuels (pyruvate and glutamate) in NBP-treated intact endothelial cells, and significantly reduced phosphorylating respiration was observed during the oxidation of succinate and especially malate in NBP-treated permeabilized endothelial cells. The observed changes in oxidative metabolism caused a decrease in ATP levels and an increase in oxygen levels in NBP-treated cells. Thus, NBPs modulate the energy metabolism of endothelial cells, leading to alterations in the cellular energy state, coenzyme Q10 redox balance, mitochondrial respiratory function, and mitochondrial turnover.
Systematic review of machine learning in PTSD studies for automated diagnosis evaluation
Authors: Wu Yuqi , Mao Kaining , Dennett Liz , Zhang Yanbo , Chen Jie 
Published: September 2023

AbstractPost-traumatic stress disorder (PTSD) is frequently underdiagnosed due to its clinical and biological heterogeneity. Worldwide, many people face barriers to accessing accurate and timely diagnoses. Machine learning (ML) techniques have been utilized for early assessments and outcome prediction to address these challenges. This paper aims to conduct a systematic review to investigate if ML is a promising approach for PTSD diagnosis. In this review, statistical methods were employed to synthesize the outcomes of the included research and provide guidance on critical considerations for ML task implementation. These included (a) selection of the most appropriate ML model for the available dataset, (b) identification of optimal ML features based on the chosen diagnostic method, (c) determination of appropriate sample size based on the distribution of the data, and (d) implementation of suitable validation tools to assess the performance of the selected ML models. We screened 3186 studies and included 41 articles based on eligibility criteria in the final synthesis. Here we report that the analysis of the included studies highlights the potential of artificial intelligence (AI) in PTSD diagnosis. However, implementing AI-based diagnostic systems in real clinical settings requires addressing several limitations, including appropriate regulation, ethical considerations, and protection of patient privacy.
Narbenpflege: Unterstützen Sie den Heilungsprozess Ihrer Haut
Authors: Rathay Uwe 
Published: September 2023

SummaryEine Narbe entsteht als Teil des natürlichen Heilungsprozesses der Haut nach Verletzungen oder Operationen. Obwohl es unmöglich ist, Narben vollständig zu vermeiden, können Sie selbst aktiv dazu beitragen, dass die Narben unauffälliger werden und sich besser an Ihre Haut anpassen. Die richtige Narbenpflege ist ein wichtiger Schritt auf dem Weg zur optimalen Heilung.
Prüfungsthema: Invasiv
Authors: Schmid Eva C 
Published: September 2023

SummaryLiebe Heilpraktikeranwärter – mit diesen Karteikarten wollen wir Sie bei der Vorbereitung auf die mündliche Heilpraktikerüberprüfung unterstützen. Viel Erfolg beim Lernen wünscht Ihnen HP Eva C. Schmid!
Construction of Migraine Knowledge Graph Based on Diagnosis and Treatment Guidelines of Integrative Medicine
Authors: Jiang Yanhua , Qiu Shiqing , Guo Zhuang , Ren Huiling , Li Xiaoying , Gao Dongping , Jing Zhiwei , Wang Junwen 
Published: September 2023

AbstractOur objective was to transform the text data in migraine diagnosis and treatment guidelines into a visualized knowledge graph by using knowledge graph technology, visually display the clinical diagnosis and treatment process, and provide assistance for the standardization of diagnosis and treatment of migraine with integrative medicine.Manual extraction, knowledge fusion, and standardization were performed on the text data in the migraine diagnosis and treatment guidelines. Combined with the clinical diagnosis and treatment process, the data of Chinese and Western medicine diagnosis and treatment of migraine were visualized and stored through the Neo4j graph database.A knowledge graph of Chinese and Western medicine diagnosis and treatment of migraine including 616 entities and 615 entity relationships was constructed, which realized the visual display of the diagnosis and treatment process of integrative medicine for migraine including examination, diagnosis, and treatment.Based on the guidelines for the diagnosis and treatment of migraine, this study visualized the diagnosis and treatment process of integrative medicine for migraine through knowledge graph technology, which is of great significance for the clinical implementation of relevant guidelines for the diagnosis and treatment and the standardization of integrative medicine diagnosis and treatment for the dominant diseases in Chinese medicine.
Histology and Histochemistry Study of Keloid Following Intralesional Steroid Injections
Authors: Ganguly Dr. A.C. , Bhattacharyya Dr. Aparna , Sanyal Dr. Sabitri , Ghose Dr. Parag , Roy Dr. Manimala , Roy Dr. Anup 
Published: September 2023

AbstractIn the present series, Intra keloidal injections of steriod are given to alleviate symptoms and to promote regression. The present study also highlights natural history of keloids, results after intrakeloidal injection of hydrocortisone and histochemical changes in the keloid after the injection therapy.
Squamous Cell Carcinoma in a Child of 6 Years- (A Case Report)
Authors: Kumar Dr. Amarendra , Verma Dr. P.K. 
Published: September 2023

AbstractA male child, 6 years old, presented with a swelling of over 1 year duration on the scalp. Swelling had gradually increased in size and had ulcerated. There was sanguinous discharge off and on from the lesion.
Orbital Varix and Its Surgical Correction - A Case Report
Authors: Sharma Dr. P.K. , Shukla Dr. B. , Tripathi Dr. B.M. , Malik Dr. R. 
Published: September 2023

AbstractA Young patient presented with left unilateral proptosis and Orbital venography was suggestive of orbital vari on left side. An easy and effective operative procedure was planned. The superficial veins around orbit were ligated. Result was acceptable and without complications. This proved an effective and simple approach as against trans-cranial or orbital approach for surgical removal of vari.
Hegemonic orders and the idea of history
Authors: McKeil Aaron 
Published: September 2023

AbstractThis article makes the case that the literature of hegemonic orders and debates on the crisis of US hegemony have been shaped and up to a point intellectually confined by a tradition or idea of world history understood as a series of hegemonic powers. This tradition of history as a succession of hegemonic powers is traced from ancient to modern sources, later reconstituted as a theoretical discourse. In drawing attention to the historical traditions underpinning this literature, these findings contribute to advancing the historiography of International Relations and to studying the role of multiple contemporaneous histories in the emerging international order.
Electronic structure study of H3BXH3 (X═B, N and P) as hydrogen storage materials using calculated NMR and XPS spectra
Authors: Wang Feng , Chong Delano P. 
Published: September 2023

Boron-based materials have been used for hydrogen storage applications owing to their high volumetric and gravimetric hydrogen density. The present study quantum mechanically investigates the electronic structures of three compounds: diborane (DB, B2H6), ammonia borane (AB, H3BNH3) and phosphine borane (PB, H3BPH3). The exploration is facilitated using calculated nuclear magnetic resonance (NMR) chemical shifts, together with outer valence ionisation potentials (IP) and core electron binding energy (CEBE). The findings show a distinct electronic structure for diborane, differing notably from AB and PB, which exhibit certain similarities. Noteworthy dissimilarities are observed in the chemical environments of the bridge hydrogens and terminal hydrogens in diborane, resulting in a substantial chemical shift difference of up to 5.31 ppm. Conversely, in AB and PB, two distinct sets of hydrogens emerge: protic hydrogens (Hp–N and Hp–P) and hydridic hydrogens (Hh–B). This leads to chemical shifts as small as 0.42 ppm in AB and as significant as 3.0 ppm in PB. The absolute isotropic NMR shielding constant (σB) of 11B in DB is 85.40 ppm, in contrast to 126.21 ppm in AB and 151.46 ppm in PB. This discrepancy indicates that boron in PB has the most robust chemical environment among the boranes. This assertion finds support in the calculated CEBE for B 1s of 196.53, 194.01 and 193.93 eV for DB, AB and PB respectively. It is clear that boron in PB is the most reactive atom. Ultimately, understanding the chemical environment of the boranes is pivotal in the context of dehydrogenation processes for boron-based hydrogen storage materials.
Effect of curvature on bilayer thickness of liposome suspensions in water
Authors: Pal Ankush , Khakhar Devang , Ray Debes , Aswal Vinod K 
Published: September 2023

Abstract
The bilayer thickness of different sizes of SOPC lipid liposomes is measured using small-angle neutron scattering (SANS) at 30 °C and a model is developed to estimate the bilayer thickness of liposome based on its diameter. Three different sizes of liposome suspensions are prepared by extruding the suspension through 30 nm, 100 nm, and 200 nm membrane pore sizes. The bilayer thickness of liposomes is measured for these suspensions using small-angle neutron scattering and the results show a slight reduction in bilayer thickness as liposome size increases. The average diameter of liposomes in these extruded suspensions varies from 59 nm to 109 nm as measured by dynamic light scattering. A model is developed that calculates the bilayer thickness depending on the diameter of the liposome. The model shows a decrease in bilayer thickness as liposome size increases. However, the calculated bilayer thickness drops to a very small extent with the increase in liposome diameter. We also study the effect of the addition of ethanol on the bilayer thickness of liposomes. SANS measurements find that the bilayer thickness of liposomes decreases after adding ethanol to liposome suspensions. The decrease in bilayer thickness in ethanol is of similar extent for various sizes of liposomes and it reduces by 12%–15% at a concentration of 20 vol% ethanol.
A promising optoelectronic and thermoelectric response of full Heusler Na2TlX (X = Bi, Sb) alloys: a DFT approach
Authors: Ain Qurat ul , Qaid Saif M H , Yousaf Masood , Alkadi Muath , Iqbal Abu Bakar , Ahmed Abdullah Ahmed Ali , Munir Junaid 
Published: September 2023

Abstract
The energy conversion efficiency is one of the attributes that make Heusler alloys an extraordinary candidate for thermoelectric applications. In this paper, we have examined the electronic structure, elastic, optical and transport characteristics of full Heusler Na2TlX (X = Bi, Sb) alloys using DFT. The electronic properties are analyzed by utilizing modified Becke Johnson (mBJ) potential. The negative formation energies and optimization results reveal the stable phases of both alloys. The electronic properties exposed the semiconductor nature of both alloys. The elastic stability is obtained from various elastic parameters. The optical response of these alloys has been studied in depth by evaluating the real and imaginary dielectric functions, optical loss, refractive index and absorption coefficient. Furthermore, the thermoelectric properties are computed, which demonstrate the high electrical conductivity, Seebeck and ZT values for both alloys. The above computed attributes favor the use of studied alloys in green energy and optoelectronic applications.
Photo-induced flexible semiconductor CdSe/CdS quantum rods alignment
Authors: Zhang Wanlong , Schneider Julian , Prodanov Maksym F. , Vashchenko Valerii V. , Rogach Andrey L. , Yuan Xiaocong , Srivastava Abhishek K. 
Published: September 2023

Abstract
The anisotropic absorption and emission from semiconductor CdSe/CdS quantum rods (QRs) provide extra benefits among other photoluminescence nanocrystals. Using photo-induced alignment technique, the QRs can be oriented in liquid crystal polymer matrix at a large scale. In this article, a 2D Dammann grating pattern, within “SKL” characters domains aligned QRs in composite film, was fabricated by multi-step photo exposure using several photo masks, and a continuous geometric lens profile pattern aligned QRs was realized by the single step polarization converting holographic irradiation method. Both polarized optical microscope and fluorescence microscope are employed to determine the liquid crystal director profiles and QRs anisotropic excitation properties. We have been able to orient the QRs in fine binary and continuous patterns that confirms the strong quantum rod aligning ability of the proposed method. Thus, the proposed approach paves a way for photo-induced flexible QRs alignments to provide a highly specific and difficult-to-replicate security application at a large scale.
Analysis of signal waveform from a midsize liquid argon detector
Authors: Zhao K.K. , Guan M.Y. , Liu J.C. , Yang C.G. , Lin S.T. 
Published: September 2023

Abstract
The midsize single-phase liquid argon prototype detector,
operating at the surface laboratory, is designed to measure
scintillation light emitted by the liquid argon (LAr). The detector
employs 42 8-inch photomultiplier tubes (PMT) to collect the
light. By analyzing the waveform of the signal, important detector
characteristics such as the slow decay time constant that
characterizes the purity of the liquid argon can be obtained. To
describe the signal waveform, a model, which takes into account the
liquid argon emission decay times together with the TPB re-emission
process as well as the signal reflection effects, is used. The TPB
re-emission process is introduced using a three-exponential time
structure. Additionally, experimental results provide comprehensive
validation for a post-peak hump structure, which is attributed to
signal reflection.
One-loop beta-functions of quartic enhanced tensor field theories
Authors: Ben Geloun Joseph , Toriumi Reiko 
Published: September 2023

Abstract
Enhanced tensor field theories (eTFTs) have dominant graphs that differ from the melonic diagrams of conventional tensor field theories. They therefore describe pertinent candidates to escape the so-called branched polymer phase, the universal geometry found for tensor models. For generic order d of the tensor field, we compute the perturbative β-functions at one-loop of two just-renormalizable quartic eTFT coined by + or ×, depending on their vertex weights. The models + has two quartic coupling constants

(
λ
,

λ

+

)

, and two 2-point couplings (mass, Za
). Meanwhile, the model × has two quartic coupling constants

(
λ
,

λ

×

)

and three 2-point couplings (mass, Za
,

Z

2
a

). At all orders, both models have a constant wave function renormalization: Z = 1 and therefore no anomalous dimension. Despite such peculiar behavior, both models acquire nontrivial radiative corrections for the coupling constants. The RG flow of the model + exhibits a particular asymptotic safety:

λ

+

is marginal without corrections thus is a fixed point of arbitrary constant value. All remaining couplings determine relevant directions and get suppressed in the UV. Concerning the model ×,

λ

×

is marginal and again a fixed point (arbitrary constant value), λ, µ and Za
are all relevant couplings and flow to 0. Meanwhile

Z

2
a

is a marginal coupling and becomes a linear function of the time scale. This model can neither be called asymptotically safe or free.
Growth Responses of Ten Soybean (Glycine max L.Merril). Genotypes on Trichoderma sp. Application in Suboptimal Land
Authors: Suryawati A , Lagiman  , Widayanto B 
Published: September 2023

Abstract

The obstacles that cause soybean productivity to decline are due to fierce competition in land use with other commodities that are also strategic, such as corn and chili. This also has an impact on the decrease in crop area by about 5% per year, higher than the projected soybean productivity which increases by 2% per year. In addition, soybean harvested land is also widely diverted to the non-agricultural sector due to economic demands and the rate of population growth. One of the efforts to overcome competition in land use through the use of suboptimal land i.e beach sand for soybean planting. The general purpose of this research is to obtain the growth responses of ten soybean genotypes on Trichoderma sp.application, in Samas beach sand, Bantul, Yogyakarta, Indonesia in May-July 2022. The research method is Split Plot Design in a Randomized Complete Block Design (RCBD) with 3 blocks. As the main plot, there are two doses of Trichoderma sp. consisting of T1 = 0.3 kg / plot, and T2 = 0.6 kg / plot. As the sub plot are the ten of soybean genotype namely: G1 = Dena 2; G2 = Argomulyo; G3 = Grobogan; G4 = Dena-1; G5 = Gepok Kuning; G6 =Dega 2; G7=Devon 1; G8= Anjasmoro G9= Demas 1 and G10=Dega 1 The data were analyzed using analysis of variance at α=5% followed by Duncan test at signification level α = 5%. The results showed that there was no interaction between Trichoderma sp and ten soybean genotypes on all variables. Plant height at 21 and 35 days after planting and stem diameter at 21 days after planting for soybean genotype of Dena, Gepok Kuning and Demas 1 had smaller than another genotypes, but they were not significant at 49 days after planting. Dose of Trichoderma sp 0,3kg/plot and 0.6 kg/plot had the same effect on all variables, it also protected the plants from desease.
Optimization of Mustard Pakcoy Growth: The Influence of Media Composition and Coconut Water Concentration
Authors: Ramadhani M F , Prihatiningrum A E , Abror M. 
Published: September 2023

Abstract
This research aimed to investigate the effect of different media compositions and varying coconut water concentrations on the growth and yield of mustard pakcoy (Brassica rapa var. parachinensis). The study was conducted in Modong Village, Sidoarjo Regency, with further laboratory analysis at the Faculty of Science and Technology, Universitas Muhammadiyah Sidoarjo. The experimental design followed a Randomized Block Design (RAK) in a factorial arrangement with two primary factors (media composition and coconut water concentration) and four replications. While no significant interaction was observed between the media composition and the coconut water concentration, independent effects of each factor were notable. The media composition significantly influenced the leaf count at 7, 28, and 35 days after planting (DAP) and the wet weight at 35 DAP. The optimum media composition included 2 kg of topsoil, 90 g of goat manure, and 45 g of rice husk charcoal per polybag, which resulted in the highest leaf count and wet weight. Additionally, coconut water concentration significantly affected the stem diameter at 35 DAP, with a concentration of 100 ml per liter of water yielding the maximum stem diameter. The findings imply potential growth optimization strategies for mustard pakcoy, enhancing yields via targeted alterations in growing media and the use of coconut water, which could be of international interest to agronomists, horticultural scientists, and sustainable agriculture practitioners.
Enhanced Melon Cultivation: An Application of Hydroponic Nutrient Formulation for Superior Yield and Quality
Authors: Supriyanta B , Florestiyanto M Y , Widowati I 
Published: September 2023

Abstract
This study, conducted from June to September 2022 in greenhouse CV. Agroniaga, aimed to enhance melon (Cucumis melo L.) productivity and quality using superior seed varieties and a hydroponic system. Utilizing a Completely Randomized Design (CRD), the experiment examined two melon varieties, Dalmatian (G1) and Sweet D25 (G2), under four nutrient formulations: F1 (vegetative and generative N3), F2 (vegetative, generative 1a and 2a), F3 (vegetative, generative 1b and 2b), and F4 (leaf goodplant, fruit goodplant). Statistical analysis was performed at a significance level of 5%. The results indicated that the F3 nutrient formulation, with specific nitrate, ammonium, phosphorus, and potassium concentrations at different growth stages, achieved high-quality melons with enhanced productivity. These findings hold significant implications for horticultural practices, promoting a sustainable, efficient strategy for superior melon cultivation and potentially contributing to the economic development in the sector.
Terra Rossa Soil as an Adsorbent to Remove Hexavalent Chromium in Aqueous Solutions
Authors: Mulyanto D , Munawar A , Widodo R A 
Published: September 2023

Abstract
Kaolinite is a phyllosilicate clay of type 1:1 which is usually associated with iron oxides in nature. The clay is abundant in Terra Rossa soils which is located in the Gunungkidul, karst area. Based on the structure and nature of it’s the charge, it has the potential to adsorb anionic heavy metals, especially hexavalent chromium. Heavy metal chromium in the form of hexavalent is very dangerous for human health and the metal is mostly produced from the waste of leather tanning factories that are widely available in Yogyakarta. The purpose of this study was to investigate the possibility of using Terra Rossa soil as an adsorbent to remove heavy metal Cr (VI) from aqueous solution. The experiment was carried out by mixing the adsorbent with a dose of: 1 – 4.5 grams of fine soil, Φ 0.5 mm into a 50 ml solution containing 10 ppm chromium with pH 5 and 3. Stirred at 200 rpm for 2 hours, then centrifuged 3500 rpm for 20 minutes. The filtrate was given phosphoric acid and diphenyl carbazide and then measured using a spectrophotometer with a wavelength of 540 nm. The results showed that the average percentage of chromium removal at pH 5 = 30%, while pH 3 = 49%. The adsorbent absorption (mg/g) decreased in line with increasing adsorbent dose. Absorption graphs of Freundlich and Langmuir models in pH3 solution show R2=0.9264 and 0.9361 respectively, while in pH5 solution the R2 values are 0.3752 and 0.3461, respectively. Adsorption capacity according to Freundlich = 1.7331 mg/g, while according to Langmuir = 5.28 mg/g with adsorption site affinity 0.1894 L/mol.