bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of epigenetic modifier on the developmental competence and quantitative expression of genes in male and female buffalo (Bubalus bubalis) cloned embryos
Authors: Sandhu Anjit , Mohapatra Sushil K. , Singh Manoj K. , Singla Suresh K. , Chauhan Manmohan S. , Manik Radhey S. 
Published: January 2023

SummaryAdult male and female Murrah buffalo fibroblast cells were used as donors for the production of embryos using handmade cloning. Both donor cells and reconstructed embryos were treated with 50 nM trichostatin-A (TSA) and 7.5 nM 5-aza-2′-deoxycytidine (5-aza-dC). The blastocyst rate of both treated male (40.1% ± 2.05) and female (37.0% ± 0.83) embryos was significantly lower than in untreated control males (49.7% ± 3.80) and females (47.2% ± 2.44) but their apoptotic index was lower (male, control: 5.90 ± 0.48; treated: 4.96 ± 0.31): (female, control: 8.11 ± 0.67; treated: 6.65 ± 0.43) and epigenetic status in terms of global acetylation and methylation of histone was significantly improved. The expression level of hypoxanthine-guanine phosphoribosyltransferase (HPRT) was higher (P < 0.05) and that of PGK, G6PD, OCT 4, IFN-tau and CASPASE3 was significantly lower (P < 0.05) in treated male blastocyst than control and the expression levels of DNMT1, IGF1R and BCL-XL were not significantly different between the two groups. In the female embryos, the relative mRNA abundance of OCT4 was significantly higher (P < 0.05), and that of XIST and CASPASE3 was significantly lower (P < 0.05) in the epigenetic modifier-treated group compared with that of the control group, whereas the expression levels of HPRT, PGK, G6PD, DNMT1, IFN-tau, IGF1R and BCL-XL were not significantly different between the two groups. In both embryos, a similar effect of treatment was observed on genes related to growth and development, but the effect on the expression of X-linked genes varied. These results indicate that not all X-linked genes respond to TSA and 5-aza-dC treatment in the same manner.
Vintage article: the effect of monetary policy shocks in the UK: an external instruments approach
Authors: Görtz Christoph , Li Wei , Tsoukalas John , Zanetti Francesco 
Published: January 2023

AbstractThis paper uses vector autoregression model analysis to identify monetary policy shocks on UK data using surprise changes in the policy rate as external instruments and imposing block exogeneity restrictions on domestic variables to estimate parameters from the viewpoint of the domestic economy. The results show large and persistent effects of monetary policy shocks on the domestic economy and point to the critical role of exchange rates and term premia. The analysis resolves important empirical puzzles of traditional recursive identification methods.
Crisis management: the perspectives of physicians working in family physician teams in Lithuania
Authors: Budrevičiūtė Aida , Raila Gediminas , Paukštaitienė Renata , Valius Leonas 
Published: January 2023

Abstract

Aim:
To assess the opinions of physicians working in family physician teams regarding COVID-19 (threat perception, overall work satisfaction, patient satisfaction with services provided, patient access to services, and the need for new tools for service provision).

Methods:
An anonymous survey of physicians (N = 191) working in family physician teams. Questionnaires were distributed among family physicians with the permission of the managers of their institutions and were collected by the lead researcher within 1–8 weeks. The quantitative study was conducted from 21 June 2021 to 17 September 2021. In total, 398 questionnaires were distributed, yielding a response rate of 48%, or 9% of the total population. Thirty-nine primary health care institutions (PHCIs) were randomly selected for the study: 11 public and 28 private.

Findings:
Older respondents and those with more years of work experience strongly agreed that the COVID-19 pandemic threatened their lives and safety, as well as that of their colleagues. Work satisfaction decreased during the pandemic among older respondents, those with more years of work experience, and those who had been employed at their current institution for longer. Respondents with more work experience believed that patient satisfaction with the services provided by their family medical institution decreased. Older respondents with more work experience asserted that patient access to services decreased during the pandemic. Physicians working further away from urban centers indicated a greater need for new tools in the effort to provide consultations compared to city-based physicians.

Conclusions:
The current health care crisis prompted by the COVID-19 pandemic is defined by the perception of threats to life and safety among physicians, an overall drop in their work satisfaction, decreased patient satisfaction with services provided, reduced patient access to services, and a greater need for new tools for providing consultations.
Identifying practical clinical problems in active euthanasia: A systematic literature review of the findings in countries where euthanasia is legal
Authors: Kono Madoka , Arai Nana , Takimoto Yoshiyuki 
Published: January 2023

AbstractObjectivesCurrently, active euthanasia is legalized in only 7 countries worldwide. These countries have encountered problems in its implementation. The study aims to summarize the practical clinical problems in the literature on active euthanasia.MethodsA systematic literature review was conducted using 140 works consisting of 130 articles from PubMed and EthxWeb and data from 10 euthanasia laws.ResultsAfter reviewing the specific problems reported to be associated with euthanasia in each country, 5 problems were extracted: many ambiguous conditions with room for interpretation, insufficient assurance of voluntariness, response to requests for euthanasia due to psychological distress, conscientious objection, and noncompliance by medical professionals.Significance of resultsMultiple ambiguous conditions that are open to interpretation can result in a “slippery slope phenomenon.” An insufficient guarantee of voluntariness violates the principle of respect for autonomy, which is the underlying justification for euthanasia. In cases of euthanasia due to mental anguish, a distinction between a desire for death caused by psychological pain alone prompted by mental illness and a desire for death caused by mental symptoms prompted by physical illness is essential. Conscientious objection should remain an option because of the heavy burden placed on doctors who perform euthanasia. Noncompliance by medical professionals due to ignorance and conflicts regarding euthanasia is contrary to procedural justice.
Psychometric properties of the Turkish version of the Palliative Nursing Care Quality Scale
Authors: Mollaoğlu Mukadder , Boy Yasemin 
Published: January 2023

AbstractObjectivesMeasuring tools are essential in assessing the quality of care. This study aimed to evaluate the validity and reliability of the Turkish version of the Palliative Nursing Care Quality Scale (PNCQS-T) and the sociodemographic characteristics affecting the quality of care.MethodsThis methodological study, whose linguistic equivalence was confirmed by the translation/back translation method, was carried out with the participation of 209 nurses. Personal Information Form and PNCQS-T were used as data collection tools. Construct validity was determined by confirmatory factor analysis (CFA). Reliability was tested with internal consistency and item-total correlation coefficients.ResultsAdaptation results showed that the Turkish version of the scale is adequate for linguistic and content validation. The Turkish adaptation’s original scale of 20 items was reduced to 18. As in the original scale, all items were combined under a single dimension in the Turkish adaptation. Modified CFA indicated a well-fitting model. PNCQS-T explained 42.1% of the total variance. Cronbach’s alpha value was 0.92. The lowest score obtained from the scale is 18; the highest score is 90. Higher scores indicated that the palliative care provided by nurses was of good quality.Significance of resultsThe Turkish version of the PNCQS-T is reliable for assessing the quality of palliative care provided by nurses in Turkey.
Sipping tea, plastics performing: representational and materialist politics of boba tea consumption in contemporary China
Authors: Wu Ka-ming 
Published: January 2023

AbstractIn a single serving of boba tea, the non-human actors of the tall plastic cups, plastic dome lids, and the giant plastic straws dominate, but receive little attention. This article uses recent theories and discussions of new materialism to bring together cultural analysis of the boba tea consumption phenomenon that could be relevant for reflecting on a sustainable future. The article contributes to social research of waste by focusing on the mediating functions of plastic before it becomes waste. My central argument is that plastic is not merely a physical and impartial container in the contemporary food and beverage industry. It plays an indispensable role in the visualization, mass mediation, and consumption of the boba tea beverage. While current waste research often focuses on the “afterlife” of plastic waste as it relates to underclass waste workers, recycling economy and global waste trade, this article highlights the performative function of plastic as it changes the way we imagine time, gender, and waste. I show it is the plastic cup that enables boba tea to be so visually and gastronomically satisfying in an age when the photogenicity and “Instagrammability” of food and beverage have become more relevant to taste and distinctions.
The impact of economic institutions on government policy: does contract-intensive economy promote impartial governance?
Authors: Mousseau Demet Yalcin 
Published: January 2023

AbstractThe objective of this study is to show how contract-intensive economic institutions can promote diversity and inclusion of social and political groups in economic and business opportunities provided by governments. Building on the interdisciplinary political economy and governance literatures, two types of economic institutions are identified: rent-seeking and contract-intensive. It is argued that rent-seeking economic activities can reinforce in-group norms, gift-giving practices, and governments' discrimination of groups. However, when contract-intensive activities increase in an economy, they can enhance diversity and inclusion of groups in the marketplace creating opportunity structures outside the state and as businesses press governments toward greater impartiality. Analyses of 165 countries from 1961 to 2011 show that a one standard deviation increase in contract-intensive economic activity is associated with a substantial 18 percent increase in the equality of access to state business opportunities for both social and political groups in the long run.
A 5G rotated frame radiator for ultra wideband microwave communication
Authors: Varun Yadav Manish , Baudha Sudeep , Sanghi Vaibhav 
Published: January 2023

AbstractA 5G rotated frame radiator for multiple applications is presented in the following paper. The presented geometry is capable of radiating the large frequency band from 2.91 to 12.17 GHz, which covers the 5G-(I) sub-6 GHz band, X-band communication with high efficiency. The impedance bandwidth of the radiator is 128%, with an electrical size of 0.24 λ × 0.24 λ × 0.15 λ in lambda. The antenna is simulated with an FR4 substrate using CST Simulator. 06-stages evolution process is also investigated by simulations, and corresponding S-parameter results are presented. Antenna's design comprises a patch in a rotated square fractal-like frame fed by a microstrip line. The proposed structure also demonstrates stable radiation patterns across the operating bandwidth. The proposed radiator has a high gain of 3.8 dBi, and an efficiency of 85%, which claimed that UWB range of the designed antenna. Therefore, it is useful for 5G-(I) sub-6 GHz band, X-band applications, including mobile, radar, and satellite microwave communication.
Solar Intensity Dispersing (SID) Concept for CubeSat Spectral CLARREO‐Like Radiance Measurements
Authors: Matthews G. 
Published: January 2023

AbstractNRC Decadal Surveys stated that the most critical goal for orbital climate measurements was improving accuracy. This is so comparisons can be better made with models, tuning theory to match the truth. That gives confidence in model predictions of future global cloud albedo warming signals, estimated to be only 0.8%/decade or less. This work considers goals of a future mission CLARREO, currently in the development phase. CLARREO's Earth viewing optics intend to scan lunar radiance for tracking calibration changes, within both a high wavelength and high spatial resolution spectrometer. The current NASA CLARREO design will attempt absolute calibration from the space station by attenuating known solar flux, using pinholes and time under‐sampling. This study presents a cheaper and potentially more effective alternative, instead using the Sun as a near direct absolute calibration target. It does this spreading sunlight over a large solid angle, before integrating signals taken from a spinning orbiting CubeSat. Additionally, after reviewing actual orbital data comparisons, the realistic accuracy of cross‐orbit satellite to satellite calibration is shown several percent at best, even for a perfect CLARREO device (far short of the desired ±0.3% quoted by NASA). That is compared to the accuracy achievable from an absolute lunar spectral characterization from this CubeSat called “MERBE‐Sat,” acting as a transfer for a climate observation system, perhaps better than ±0.3% error. Although discussed individual components of MERBE‐Sat are mostly of high TRL Level, this work suggests experimentation to raise the net TRL level of the new entire concept.
Synoptic Variability in Satellite Altimeter‐Derived Radar Freeboard of Arctic Sea Ice
Authors: Nab Carmen , Mallett Robbie , Gregory William , Landy Jack , Lawrence Isobel , Willatt Rosemary , Stroeve Julienne , Tsamados Michel 
Published: January 2023

AbstractSatellite observations of sea ice freeboard are integral to the estimation of sea ice thickness. It is commonly assumed that radar pulses from satellite‐mounted Ku‐band altimeters penetrate through the snow and reflect from the snow‐ice interface. We would therefore expect a negative correlation between snow accumulation and radar freeboard measurements, as increased snow loading weighs the ice floe down. In this study we produce daily resolution radar freeboard products from the CryoSat‐2 and Sentinel‐3 altimeters via a recently developed optimal interpolation scheme. We find statistically significant (p < 0.05) positive correlations between radar freeboard anomalies and modeled snow accumulation. This suggests that, in the period after snowfall, radar pulses are not scattering from the snow‐ice interface as commonly assumed. Our results offer satellite‐based evidence of winter Ku‐band radar scattering above the snow‐ice interface, violating a key assumption in sea ice thickness retrievals.
D Region Electron Density Derived From Sprite Observations
Authors: Stenbaek‐Nielsen H. C. , Liu N. Y. , McHarg M. G. , Harley J. 
Published: January 2023

AbstractFour upward propagating streamers in two carrot sprites over northwest Texas were recorded at 100,000 frames per second at 07:46:35 UT, 2 June 2019, from the Langmuir Laboratory near Socorro, New Mexico. The streamers reached velocities of 50–80 × 106 m/s with accelerations up to 25 × 1010 m/s/s. The upward motion ended with the top of the streamers near 90 km altitude. At this time, the streamers reached maximum brightness. The streamer head then dissolved and the brightness decayed exponentially with time constants between 0.078 and 0.097 ms. We interpret the dissolution and decay to be the result of interaction with the bottom of the ionosphere. Assuming the decay to be dictated by electric field relaxation, the ambient D region electron density would be 107 to 108 m−3. The analysis suggests that sprite observations can provide multipoint measurements of the D region ionosphere impacted by powerful lightning capable of triggering sprites.
Spectral Wave Dissipation Over a Roughness‐Varying Barrier Reef
Authors: Sous Damien , Martins Kévin , Tissier Marion , Bouchette Frédéric , Meulé Samuel 
Published: January 2023

AbstractThe present paper reports on a field experiment performed over a shallow, roughness‐varying barrier reef at Maupiti island, French Polynesia. The spectral wave energy balance is examined, outside the breaking zone and accounting for non‐linear transfers and mean current, to estimate the wave friction factor. This latter varies from 0.05 to 4, with dependence on the ratio between near‐bed orbital amplitude and roughness height well predicted by an adjusted parameterization from Madsen (1995). The present results are discussed with respect to other field data recovered on coral and rocky grounds.
Quantifying the Effect of Wind on Volcanic Plumes: Implications for Plume Modeling
Authors: Dürig Tobias , Gudmundsson Magnús T. , Dioguardi Fabio , Schmidt Louise Steffensen 
Published: January 2023

AbstractThe considerable effects that wind can have on estimates of mass eruption rates (MERs) in explosive eruptions based on volcanic plume height are well known but difficult to quantify rigorously. Many explicitly wind‐affected plume models have the additional difficulty that they require the use of centerline heights of bent‐over plumes, a parameter not easily obtained directly from observational data. We tested two such models by using the time series of varying plume heights and windspeeds of the 2010 eruption. The mapped fallout and photos taken during this eruption allow us to estimate the plume geometry and to empirically constrain input parameters for the two models tested. Two strategies are presented to correct the difference in maximum plume height and centerline height: (a) based on plume radius, and (b) by using the plume type parameter Π, which quantifies the relative influence of buoyancy and cross‐wind on the plume dynamics, to discriminate weak, intermediate and strong plumes. The results indicate that it may be more appropriate to classify plumes as either wind‐dominated, intermediate or buoyancy‐dominated, where the relative effects of both wind and MER define the type. The analysis of the Eyjafjallajökull data shows that the MER estimates from both models are considerably improved when a plume‐type dependent centerline‐correction is applied. For one model, we varied the wind entrainment coefficient β. For this particular eruption, we find that the best value for β lies between 0.28 and 0.36, unlike previous suggestions that set this parameter to 0.50.
Mars' External Magnetic Field as Seen From the Surface With InSight
Authors: Mittelholz A. , Johnson C. L. , Fillingim M. , Grimm R. E. , Joy S. , Thorne S. N. , Banerdt W. B. 
Published: January 2023

AbstractThe magnetometer of the InSight mission operated on the Martian surface from November 2018 until May 2022. Previously, satellites have provided information on the Martian magnetic field environment from orbit; however, the degree to which external fields penetrate to and interact with the surface could not be studied prior to the InSight landing. Here, we present an overview of the complete surface magnetic field data from InSight sols 14 to 1241 that display different external magnetic field phenomena, transient and periodic. Periodic observations range from short period waves (100–1000s of seconds), diurnal variations, ∼26 sol Carrington rotations, to seasonal fluctuations. Transient events are observed in response to space weather and dust movement. We find that ionospheric variations are the dominant contribution as seen from the surface, while contributions from the undisturbed interplanetary magnetic field are more subtle. We discuss limitations associated with a single point measurement and opportunities that future missions could enable. Including magnetometers on future missions at a variety of locations for long‐duration continuous observations will be of great value in understanding a range of external field phenomena and will enable further investigations in different crustal magnetic field settings.
Response of Shallow Gas‐Charged Holocene Deposits in the Yangtze Delta to Meter‐Scale Erosion Induced by Diminished Sediment Supply: Increasing Greenhouse Gas Emissions
Authors: Chen Yufeng , Deng Bing , Zhang Guiling , Zhang Weiguo , Gao Shu 
Published: January 2023

AbstractRiver deltas have long been considered important carbon sinks. However, the presence of shallow gas and the processes of delta erosion caused by diminished sediment supplies could reduce the strength of the carbon sink. In this study, based on historical bathymetric data and a data set obtained from a seismic survey, we investigate the response of gas‐charged deposits in the Yangtze subaqueous delta to seabed erosion. A conservative estimate of the total methane reserves of 0.55–4.35 × 1011 mol was obtained in the delineated gassy area of ∼3,800 km2. The seismic and bathymetric data reveal a prominent erosional belt at water depths ranging from 5 to 20 m and extending from the southwestern to northeastern nearshore areas of the Yangtze subaqueous delta. Erosion is severe in the south and slight in the north due to differences in the hydrodynamic conditions, sediment erodibility, and sensitivity to sediment reduction. Seabed erosion reduces the thickness of the cap bed and the overburden pressure at the gas front, making it easier for gas to seep through the sediment column and bypass the anaerobic oxidation of methane. The good agreement between the elevated methane concentrations and the erosional belts and the spatial coincidence between the shallower gas front and pockmarks indicate that seabed erosion accelerates gas seepage activities. In the context of global deltaic degradation, the increasing greenhouse gas emissions from deltaic deposits are worthy of further attention.
Fault‐Driven Differential Exhumation in a Transpressional Tectonic Setting: A Combined Microstructural and Thermochronologic Approach From the Liquiñe‐Ofqui Fault System, Southern Andes (39°S)
Authors: Roquer Tomás , Arancibia Gloria , Seymour Nikki M. , Veloso Eugenio E. , Rowland Julie , Stockli Daniel F. , Jöns Niels , Morata Diego 
Published: January 2023

AbstractCrustal deformation in transpressive tectonic settings is partitioned across fault‐bounded tectonic blocks whose borders may represent ideal loci for enhanced rock exhumation. Field and petrographic analysis, geothermobarometry, zircon U‐Pb geochronology, and zircon and apatite (U‐Th)/He thermochronology were applied to intrusive and metamorphic rocks to investigate exhumation patterns of fault blocks delimited by the Liquiñe‐Ofqui Fault System (LOFS), Southern Andes (39°S). Our integrated analyses document the relative influences of magmatism, fault‐driven differential exhumation, and fault‐controlled geothermal flow along the LOFS. Magmatism was concentrated in the Early to Late Jurassic (∼182–151 Ma), Early Cretaceous (∼116–104 Ma), and Miocene (∼17–6 Ma). Dextral mylonitic deformation was most likely coeval with the Miocene pulse of magmatism. Tectonic exhumation occurred across a positive flower structure during the Late Miocene to Early Pleistocene (∼6–2 Ma), and affected kilometric‐scale tectonic blocks bound by N‐striking, steeply dipping faults of the LOFS. Fault‐controlled geothermal flow occurred from the Early Pleistocene to the present‐day (∼1.5 Ma‐present). Our results suggest that individual faults not only facilitate exhumation of tectonic blocks but also act as pathways for long‐term hydrothermal fluid flow.