bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Indeks Massa Tubuh Terhadap Kejadian Nyeri Desminore Primer Pada Remaja Perempuan di Dusun Tegal Mukti, Way Kanan
Authors: Widianingsih Ni Ketut , Rahim Anita Faradilla , Windarti Winda 
Published: February 2023

Periode pergantian dari masa anak-anak ke dewasa disebut dengan masa remaja. Pada remaja awal, menstruasi kadang menimbulkan ketakutan dan kekhawatiran, sebab ketika menstruasi datang biasanya disertai beberapa keluhan salah satunya yaitu nyeri haid atau sering disebut dengan Dismenore. Dismenore primer diperngaruhi oleh salah satunya faktror yaitu indeks massa tubuh (IMT). Metode penelitian yang digunakan yaitu penelitian kuantitatif statistik deskritif. Pemeriksaan indeks massa tubuh dengan menghitung berat badan dalam kilogram dibagi tinggi badan dalam meter kuadrat dan derajat nyeri menggunakan VAS. Hasil penelitian menunjukan bahwa adanya hubungan yang kuat kearah negatif antara indeks massa tubuh (IMT) dengan derajat nyeri desminore primer yaitu semakin rendah nilai IMT seseorang maka semakin tinggi derajat nyeri desminore yang dialami pada remaja perempuan di dusun tegal mukti, way kanan.
Pengaruh Pemberian Teknik Mulligan terhadap Nyeri dan Kemampuan Fungsional pada Low Back Pain Miogenik : Narrative Review
Authors: Wardhani Riska Risty , Muslim Hasyim As’ari 
Published: February 2023

Low Back pain merupakan gangguan musculoskeletal dengan tanda rasa nyeri di area sekitar punggung bawah, Insidensi banyak terjadi pada low back pain miogenik, ini meningkat sesuai dengan bertambahnya usia. intervensi fisioterapi yang digunakan untuk mengurangi nyeri dengan teknik mulligan SNAGS. Untuk mengetahui pengaruh teknik mulligan SNAGS terhadap penurunan nyeri dan kemampuan fungsional pada pasien low back pain. Narrative Review dengan metode PICO, yaitu P (Patient, Problem, Population), I (Intervention), C (Comparison), dan O (Outcome) serta memenuhi kriteria inklusi dan eksklusi. Pencarian artikel dilakukan di beberapa database yaitu Pubmed, DOAJ, dan Science Direct. Berdasarkan hasil review dari 10 artikel, terdapat 8 artikel yang menyatakan bahwa teknik mulligan terbukti efektif dalam menurunkan nyeri pada Low Back Pain, sedangkan 2 artikel lainnya menyatakan bahwa teknik terapi manual serta stabilisasi tulang belakang terbukti lebih unggul daripada teknik mulligan. Teknik mulligan terbukti efektif untuk mengurangi nyeri dan meningkatkan kemampuan fungsional,serta menjadi terapi latihan kombinasi pengobatan pada kasus Low Back Pain myogenic dengan dosis 3 set 6 kali pengulangan dan setiap set nya 10 repitisi selama 3 minggu.
KEPADATAN DAN POLA DISTRIBUSI MAKROALGA PADA DAERAH INTERTIDAL DI PERAIRAN PULAU PADEI LAUT, KECAMATAN MENUI KEPULAUAN, KABUPATEN MOROWALI, SULAWESI TENGAH
Authors: Ricky Ricky , Ramli Muhammad , Nurgayah Wa 
Published: February 2023

Makroalga merupakan kelompok alga multiseluler yang tubuhnya berupa talus yang tidak mempunyai akar, batang dan daun sejati. Penelitian ini bertujuan untuk mengetahui kepadatan dan pola distribusi makroalga di daerah intertidal di Perairan Pulau Padei Laut. Pengambilan data dilakukan pada bulan November 2020 bertempat di Perairan Pulau Padei Laut, Kecamatan Menui Kepulauan, Kabupaten Morowali, Sulawesi Tengah. Pengambilan sampel makroalga menggunakan metode transek kuadrat sepanjang 100 m tegak lurus garis pantai. Sampel makroalga yang terdapat di dalam transek kuadrat 1 x 1 m dihitung jumlah tegakan/rumpun per jenis. Berdasarkan hasil penelitian yang dilakukan, kepadatan tertinggi terdapat pada kawasan lamun dengan nilai 7,73 ind/m2. Kepadatan terendah berada pada kawasan mangrove dangan nilai kepadatan 1,02 ind/m2. Pola distribusi makroalga berdasarkan analisis indeks morisita di Perairan Padei Laut bersifat mengelompok.Kata kunci : makroalga, Kepadatan, Pola Distribusi, Pulau Padei Laut
KARAKTERISTIK GELOMBANG DI PERAIRAN TIMUR KECAMATAN KULISUSU UTARA KABUPATEN BUTON UTARA
Authors: Sarman Sarman , Ramli Muhammad , Pratikino A. Ginong 
Published: February 2023

Kecamatan Kulisusu Utara merupakan salah satu Kecamatan yang terdapat di Kabupaten Buton Utara yang memiliki luas wilayah 339,64 km2 yang terdiri dari empat belas desa yang mana wilayahnya berhadapan dengan laut banda. Kulisusu Utara memiliki beberapa desa yang berpotensi mengalami abrasi serta kerusakan fasilitas, seperti bangunan rumah, dan akses jalanan. Penelitian ini di lakukan bertujuan untuk menggetahui karakteristik gelombang berupa tinggi, periode dan transformasi gelombang lima tahun berdasarkan kecepatan angin selama tahun (2016-2020) di perairan Kulisusu Utara Buton Utara. Penelitian ini dilaksanakan pada bulan Oktober 2020- Desember 2021 di perairan Kulisusu Utara. Metode penelitian ini menggunakan metode Sverdrup-Munk-Bretchneider (SMB) untuk mendapatkan informasi kondisi gelombang dominan pada daerah penelitian. Hasil penelitian menunjukkan bahwa nilai perhitungan tinggi gelombang signifikan dan periode gelombang pada arah Timur memiliki tinggi signifikan 3.27 m dan 9.26 detik. Sedangkan tinggi gelombang dan periode gelombang pada arah Tenggara memiliki tinggi gelombang signifikan 2.93 m dan 7.51 detik. Transformasi gelombang diperoleh dari arah Timur pada saat gelombang merambat dari laut dalam menuju pantai mengalami perubahan tinggi gelombang, kemudian mendekati garis pantai tinggi gelombang akan meningkat sampai akhirnya pecah, serta mengalami pembelokan arah gelombang.Kata kunci: Karakteristik Gelombang, Kulisusu Utara, Metode SBM
KAJIAN PEMANFAATAN KARANG Millepora dichotoma SEBAGAI BIOINDIKATOR PENCEMARAN LOGAM BERAT
Authors: Armid Alrum 
Published: February 2023

Organisme karang memiliki kemampuan untuk menyerap ion-ion logam yang ada dalam lingkungan perairan laut. Biokonsentrasi logam berat timbal (Pb) dan seng (Zn) pada karang Millepora dichotoma di perairan Pulau Bokori, Kendari telah diteliti untuk menginisiasi penggunaan karang ini sebagai bioindikator pencemaran logam Pb dan Zn. Kandungan logam berat pada karang M. dichotoma dianalisis menggunakan metode Spektrofotometri Serapan Atom (SSA) pada 3 bagian tubuh karang, yaitu kerangka (skeleton), jaringan (tissue) dan alga simbiont (zooxhanthellae). Hasil penelitian menunjukkan bahwa nilai rata-rata konsentrasi logam berat Pb pada karang M. dichotoma (47,69 ppm) lebih besar dibandingkan logam berat Zn (35,68 ppm). Hal yang sama juga ditunjukkan pada nilai rata-rata Faktor Biokonsentrasi (BCF) sebesar 88314 untuk logam Pb dan 6968 untuk logam Zn. Nilai BCF di atas 1000 mengindikasikan kemampuan karang M. dichotoma dalam mengakumulasi logam berat Pb dan Zn termasuk dalam kategori akumulatif tinggi. Tingginya nilai BCF ini memberikan potensi karang M. dichotoma untuk dijadikan bioindikator atau biomonitor pencemaran logam berat (terutama Pb dan Zn) di lingkungan perairan laut.Kata kunci: Pulau Bokori, faktor biokonsentrasi, Millepora dichotoma, timbal (Pb), seng (Zn)
KAJIAN KEBERLANJUTAN IKAN KEMBUNG (RASTRELIGER KANAGUARTA) BERDASARKAN ASPEK TEKNOLOGI DI SELAT TIWORO
Authors: Tadjuddah Muslim , Irwan Nur Andi , Tahir Sampaga La Ode 
Published: February 2023

Keberlanjutan pemanfaatan sumber daya perikanan tangkap memerlukan suatu pengelolaan yang tepat dengan cara memanfaatan sumber daya tersebut dengan tetap memperhatikan kelestariannya. Sifat sumber daya perikanan merupakan sumber daya milik bersama yang rawan terhadap pemanfaatan yang berlebihan. Selat Tiworo merupakan kawasan perairan dengan banyak pulau-pulau kecil dengan potensi sumberdaya ikan yang cukup besar dan menjadi lokasi penangkapan ikan utama bagi nelayan setempat. Penelitian ini bertujuan untuk mengetahui keberlanjutan perikanan ikan kembung di perairan Selat Tiworo Kabupaten Muna Barat berdasarkan aspek teknologi. Manfaat dari penelitian ini diharapkan dapat memberikan informasi tentang status pemanfaatan ikan kembung di perairan Selat Tiworo Kabupaten Muna Barat. Permasalahan saat ini yang dihadapi oleh nelayan yang menangkap ikan kembung di Selat Tiworo antara lain: hasil tangkapan nelayan menunjukkan trend yang terus menurun, ukuran ikan yang tertangkap relatif kecil bila dibandingkan dengan ukuran ikan hasil tangkapan tahun-tahun sebelumnya yang berakibat semakin menurunnya pendapatan nelayan, alat tangkap yang digunakan untuk menangkap ikan kembung diduga masih ada yang menggunakan alat tangkap yang kurang ramah lingkungan. Keberlanjutan perikanan ikan kembung di perairan selat Tiworo dianalisis dengan menggunakan metode RAPFISH. Hasil analisis ordinansi keberlanjutan pemanfaatan ikan kembung di Selat Tiworo masuk dalam status kurang berkelanjutan. Dalam meningkatkan status keberlanjutan penangkapan ikan kembung di Selat Tiworo maka perlu dilakukan perbaikan pada atribut penggunaan alat tangkapKata kunci: keberlanjutan, ikan kembung, Selat Tiworo
KONSERVASI DAN PENGEMBANGAN HUTAN MANGROVE SEBAGAI TEMPAT EKOWISATA DI PESISIR DESA TANJUNG PINANG, KABUPATEN MUNA BARAT
Authors: Iskandar Muhammad , Ramli Muhammad , Sadarun Baru 
Published: February 2023

Hutan mangrove didefinisikan sebagai suatu tipe hutan yang tumbuh di daerah pasang surut terutama di pantai yang terlindung, laguna, muara sungai yang tergenang pada saat pasang dan bebas dari genangan pada saat surut.Tujuan dari penelitian ini adalah Untuk mengetahui kondisi hutan mangrove di pesisir Desa Tanjung Pinang, Kabupaten Muna Barat, Untuk mengetahui Konservasi Hutan Mangrove di pesisir Desa Tanjung Pinang, Kabupaten Muna Barat, dan Untuk mengetahui Pengembagan ekowisata hutan mangrove di pesisir Desa Tanjung Pinang, Kabupaten Muna Barat. Penelitian ini telah di laksanakan pada bulan September 2022 di Desa Tanjung Pinang , Kabupaten Muna Barat. Metode yang digunakan untuk menentukan stasiun dalam penelitian ini adalah metode purposife sampling setiap stasiun ditentukan transek tegak lurus dari Laut ke darat hingga terdapat 3 sub stasiun. Masing-masing sub stasiun dibagi menjadi 5 plot. Menggunakan tali rafia yang telah ditentukan ukurannya (10m x 10m), tali rafia ukuran ini digunakan untuk menentukan luas area pengamatan. Dalam plot 10x10m2, diamati dan diidentifikasi jenis serta ukuran diameter batang kategori pohon, dimana ukuran vegetasi mangrove tersebut adalah tinggi >1,5m, diameter >10cm. Berdasarkan hasil penelitian disimpulkan bahwa kondisi hutan mangrove di Desa Tanjung Pinang dalam kriteria baku kerapatan mangrove dalam kategori padat. Indeks kesesuaian Wisata (IKW) pada kawasan konservasi mangrove di Desa Tanjung Pinang “ cukup sesuai” untuk kegiatan ekowisata. pengembangan kawasan ekowisata hutan mangrove di Desa Tanjung Pinang, sudah sesuai dengan presepsi masyarakat untuk memanfaatkan hutan mangrove sebagai kawasan wisata dan sebagai fungsi penyangga kestabilan hutan mangrove.Kata kunci : Kerapatan Mangrove, Konservasi dan indeks kesesuaian wisata.
Supplemental oxygen did not significantly affect two-year mortality in patients at-risk for cardiovascular complications undergoing moderate- to high-risk abdominal surgery–A follow-up analysis of a prospective randomized clinical trial
Authors: Taschner Alexander , Fleischmann Edith , Kabon Barbara , Falkner von Sonnenburg Markus , Adamowitsch Nikolas , Horvath Katharina , Christian Thomas , Emler David , Fraunschiel Melanie , Graf Alexandra , Reiterer Christian 
Published: February 2023

BackgroundIn relatively healthy middle-aged patients, recent studies have shown that supplemental oxygen did not significantly increase one-year mortality after noncardiac surgery. If supplemental oxygen influences long-term mortality, specifically in elderly patients with cardiovascular risk-factors, remains unknown. Thus, we evaluated the effect of supplemental oxygen on two-year mortality in patients with cardiovascular risk factors undergoing moderate- to high-risk major abdominal surgery.MethodsThis is a follow-up study of a prospective, randomized, double-blinded, clinical trial. Two hundred fifty-eight patients, who were at least 45 years of age and at-risk for cardiovascular complications were randomly assigned to receive 80 vs. 30% oxygen during surgery and for the first two postoperative hours. Vital status was obtained from all patients 2 years after surgery using the national registry. Preoperative and postoperative maximum concentrations of NT-proBNP, Troponin T (TnT), Copeptin, von Willebrand Factor (vWF), static oxidation-reduction potential (sORP) and oxidation-reduction potential capacity (cORP) were tested for association with two-year mortality.ResultsThe median age of patients was 74 years (25th-75th percentile 70–78 years). 25.8% (95% CI: 17.3–32.4%) of patients in the 80% oxygen group and 22.3% (95% CI: 14.8–29.1%) in the 30% oxygen group died within 2 years after surgery. No significant difference in two-year mortality was found between patients, who received 80% oxygen concentration, versus patients, who received 30% oxygen concentration (estimated hazard ratio 1.145; 95% CI 0.693–1.893; p = 0.597). Preoperative Copeptin concentrations and postoperative maximum vWF activity were significantly associated with two-year mortality (p &lt; 0.001).ConclusionOur results are consistent with previous studies, that showed that supplemental oxygen did not increase long-term mortality. Therefore, it is becoming more evident that supplemental oxygen may not have a significant effect on long-term outcome in patients undergoing major abdominal surgery.
Outcomes of minimally invasive isolated tricuspid valve reoperation after left-side valve surgery: A single-center experience
Authors: Liu Jian , Tan Tong , Huang Huanlei , Gu Wenda , Zang Xin , Ma Jianrui , Wu Hongxiang , Liu Haozhong , Zhuang Jian , Chen Jimei , Guo Huiming 
Published: February 2023

BackgroundLate severe tricuspid regurgitation (TR) after left-side valve surgery (LSVS) is not uncommon. However, the tricuspid valve has been deemed the forgotten valve because the isolated TR is well tolerated with medication, and reoperation has a higher rate of adverse events. With the advancement of minimally invasive techniques, isolated tricuspid valve reoperation (ITVR) via totally endoscopy or transcatheter approach brings the tricuspid valve into spotlight. Our aim is to report the safety and efficacy of minimally invasive ITVR using endoscopic and transcatheter approaches.MethodsFrom October 2020 to October 2021, 21 patients with LSVS history and secondary massive TR underwent minimally invasive ITVR in our institution. Baseline characteristics, surgical outcomes and follow-up results were analyzed, and data between the totally endoscopy approach and the transcatheter approach were compared.ResultsOf the 21 cases, totally endoscopic isolated tricuspid valve surgery (EITVS) accounts for 16 (76.2%) cases, with 14 tricuspid valvuloplasty cases, and 2 tricuspid valve replacement cases; the remaining 5 (23.8%) cases underwent transcatheter tricuspid valve replacement (TTVR). The mean age was (60.0 ± 8.4) years, with 15 (71.4%) being female. Minimally invasive ITVR procedures were 100% successfully performed in all patients without any perioperative mortality, sternotomy conversion, or reoperation. During the median follow-up of 16.8 months (IQR, 13.0–20.6 months), New York Heart Association Class improved significantly from baseline (P = 0.004). TR severity was significantly improved during postoperative and follow-up period (both P &lt; 0.001). Compared with the EITVS group, the TTVR group had a higher clinical risk score [8.00 (8.00, 9.00) vs. 5.00 (3.25, 5.00), P = 0.001], but a higher success rate in reducing TR to less than grade 1+ (100 vs. 43.8%, P = 0.045) at follow-up.ConclusionIn our series, minimally invasive ITVR, including EITVS and TTVR, is a safe and feasible option for severe TR after LSVS, and presents excellent early outcomes in selected patients. TTVR is a reliable alternative for patients with high surgical risk. To improve the results of ITVR, it is necessary to improve patient’s preoperative status or perform reoperation before the onset of significant right heart failure. Further studies with a larger sample size and a longer follow-up period are awaited.
An improved method to efficiently acquire rice black-streaked dwarf virus viruliferous small brown planthoppers
Authors: Du Linlin , Zeng Bo , Li Xuejuan , Lan Ying , Guo Wei , Wang Zhaoyun , Liu Zhiyang , Zhou Yijun , Jiban Kumar Kunda , Zhou Tong 
Published: February 2023

Accurate phenotypic identification is the basis of research for resistance genetics and rice breeding for resistance to RBSDV disease. Obtaining rice black-streaked dwarf virus (RBSDV) viruliferous small brown planthoppers (SBPHs) with high transmission efficiency is an essential part of accurate phenotypic identification. Here, through quantifying number of RBSDV copies in infected rice plants, optimizing times of SBPHs fed on RBSDV-infected rice plants and leaf stage of rice seedlings, a method to acquire an RBSDV-carrying SBPH population more efficiently was improved. The results showed that rate of viruliferous SBPHs was significantly higher when fed on RBSDV-infected rice plants that had the copy numbers of RBSDV S10 of 3.0*104 and 1.1*104 than 8.3*102. Therefore, it is more efficient for SBPHs to acquire the virus when fed on RBSDV-infected rice plants that have copy numbers of RBSDV S10 above 1.1*104. The rate of viruliferous SBPHs were 50% and 54%, respectively, after the insects fed on RBSDV-infected rice plants for 7 and 9 days and being transferred to healthy rice seedlings for 5 and 3 days, which was significantly higher than those at other feeding times. The optimal inoculation leaf stage of rice seedlings was the 2-3-leaf stage (3 effective SBPHs per seedling for 72 h), but a high rate of viruliferous SBPHs may be suggested for inoculation of older rice seedlings.
In vitro assessment of Neuronal PAS domain 2 mitigating compounds for scarless wound healing
Authors: Clements Adam , Shibuya Yoichiro , Hokugo Akishige , Brooks Zachary , Roca Yvonne , Kondo Takeru , Nishimura Ichiro , Jarrahy Reza 
Published: February 2023

BackgroundThe core circadian gene Neuronal PAS domain 2 (NPAS2) is expressed in dermal fibroblasts and has been shown to play a critical role in regulating collagen synthesis during wound healing. We have performed high throughput drug screening to identify genes responsible for downregulation of Npas2 while maintaining cell viability. From this, five FDA-approved hit compounds were shown to suppress Npas2 expression in fibroblasts. In this study, we hypothesize that the therapeutic suppression of Npas2 by hit compounds will have two effects: (1) attenuated excessive collagen deposition and (2) accelerated dermal wound healing without hypertrophic scarring.Materials and methodsTo test the effects of each hit compound (named Dwn1, 2, 3, 4, and 5), primary adult human dermal fibroblasts (HDFa) were treated with either 0, 0.1, 1, or 10 μM of a single hit compound. HDFa behaviors were assessed by picrosirius red staining and quantitative RT-PCR for in vitro collagen synthesis, cell viability assay, in vitro fibroblast-to-myofibroblast differentiation test, and cell migration assays.ResultsDwn1 and Dwn2 were found to significantly affect collagen synthesis and cell migration without any cytotoxicity. Dwn3, Dwn4, and Dwn5 did not affect collagen synthesis and were thereby eliminated from further consideration for their role in mitigation of gene expression or myofibroblast differentiation. Dwn1 also attenuated myofibroblast differentiation on HDFa.ConclusionDwn1 and Dwn2 may serve as possible therapeutic agents for future studies related to skin wound healing.
Development of a mobile application for assessing reaction time in walking and TUG duration: Concurrent validity in female older adults
Authors: Pumpho Ampha , Kaewsanmung Supapon , Keawduangdee Petcharat , Suwannarat Patcharawan , Boonsinsukh Rumpa 
Published: February 2023

IntroductionThe TUG can be used to distinguish between people who fall and people who don’t fall. To evaluate cognitive dual-task performance while walking for fall prediction, TUG-dual was frequently employed. A recent study has created a mobile application that enables simple interaction to provide greater convenience for monitoring the duration of TUG, TUG-subtraction, and reaction time.ObjectiveThe research aim was to ascertain the concurrent validity of the mobile application that was developed for the clinical assessment of TUG, TUG-subtraction, and reaction time.MethodsTwenty-nine older persons participated in this study. The testing protocol involved the TUG, TUG-subtraction, and reaction time assessment. For TUG and TUG-subtraction, the duration to complete the task was recorded by the APDM Mobility Lab system and the mobile application. For the reaction time tests, the reaction times (msec) were recorded by the Multi Choice Reaction timer and the Mobile application. The TUG durations recorded by the APDM Mobility Lab system were correlated with those recorded by the mobile application to verify the concurrent validity using Pearson’s product moment correlation coefficient. Also, the reaction time by the Multi Choice Reaction timer was correlated with the mobile application. Bland-Altman plots were used to explore the existence of any systematic differences between the measurements.ResultsOur results showed very strong correlations between the TUG and TUG-subtraction duration derived from the APDM Mobility Lab system and the mobile application (r = 0.96 and 0.96, respectively). For the reaction time, the results showed a moderate correlation between the reaction time derived from the mobile application and the Multi Choice Reaction Timer (r = 0.67).ConclusionThe mobile application, which allows measurement in TUG and TUG-subtraction, is a highly valid tool for TUG duration assessment. However, this application is capable for assess the reaction time with moderate validity for reaction time assessment.