bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bolivian “Music of the Wind” in guitar works: aspects of artistic implementation
Authors: Filatova Tetiana 
Published: April 2023

The relevance of the article is to consider Bolivian guitar music as an important component of the modern South American repertoire. On the example of the works of famous composers and performers Alfredo Domínguez, Fernando Arduz, and Jilberto Rojas, connections with the folklore traditions of the country, the poetics of Bolivian "wind music", and its timbre specificity have been revealed.
Main objective of the study is to reveal aspects of the artistic embodiment of Bolivian «music of the wind» in academic guitar work. The scientific novelty of the article lies in the introduction of materials about Bolivian musical culture and guitar creativity into domestic musicological circulation.
The methodology includes methods of historical, comparative, phenomenological, structural and functional analysis to study: genre and style elements of Bolivian folk music of Indian and Creole origin in academic guitar work; organology of traditional instruments and timbre characteristics of sound; phenomena of imitation of the voices of nature, the timbres of Bolivian wind, percussion, and string-plucked instruments by modern guitar means of sound production; genealogy of rhythmic structures and their manifestations in the researched works; decorative and visual ritual attribution; correlation of associative-figurative series with timbre connotations, specific genres and intonation and chord patterns; anthropological connections of the sound space of «music of the wind» with the surrounding natural and landscape environment and the state of metaphysical dialogue of man with the surrounding world.
Results and conclusions. In the analyzed compositions («Feria», «Por la Quebrada» by A. Dominguez, «Despedida de Los Chunchos» by F. Arduz, «Guadalquivir» by J. Rojas) various resources of performing guitar technique used to imitate the voices of nature, authentic timbres of ancient Bolivian aerophones quena, erke, сaña, membranophones caja, local chordophones charango, relevant in modern conditions of collective ritual music-making practice. Sound and image connotations are correlated with the voices of Bolivian folk instruments, ritual decorations, plasticity of dance movements, visualization of natural landscapes and attribution of totemic cultures. In the process of defining genre components, the contrasts of juxtapositions were demonstrated: takirari, tonada and Andean huayño, ceremonial Indian ceremonies and sardana dance of Iberian origin, metric fluctuations of Creole and Indian rhythms, melodic movements of pentatonic nature with melismatic ornaments of the Andean type. Linguistic and genre characteristics of guitar works were investigated taking into account the anthropological experience of Bolivian scientists studying their musical and ceremonial culture, which in particular determined the search for the historical roots of musical phenomena among the exhibits of archaeological museums, exhibits of musical instruments, and artifacts of the life of indigenous peoples.
APLICAÇÃO FOLIAR DE UREIA, NÍQUEL E SACAROSE EM ESTÁDIO REPRODUTIVO DA SOJA
Authors: Dutra Kochenborger Ana Clara , Orioli Júnior Valdeci , Silva Gabriel Augusto , Martini Sargentim Mateus , Rodrigues Torres José Luiz 
Published: April 2023

A aplicação foliar dos nutrientes N e Ni em estádio reprodutivo da soja pode trazer benefícios à cultura da soja. No entanto, ao se utilizar a ureia como fonte para essa prática é comum a ocorrência de fitotoxidez nas folhas. Essa fitotoxidez pode ser reduzida pela adição de Ni e sacarose à calda de pulverização. Assim, o presente trabalho teve por objetivo avaliar a aplicação de uma solução com diferentes concentrações de ureia, com e sem a presença de Ni e sacarose. O delineamento experimental utilizado foi em blocos casualizados, em esquema fatorial 4x2x2, com quatro repetições. Os tratamentos foram constituídos de quatro concentrações de ureia (0, 5, 10 e 15% m/v), na presença ou ausência de Ni (30 g ha-1 de Ni), com e sem adição de sacarose (1 mol L-1), aplicadas via folha no início da fase de enchimento de grãos. A aplicação foliar de ureia se mostrou viável somente com a adição de sacarose à calda de pulverização. A adição de sacarose na calda elimina a fitotoxidez nas plantas de soja causada pela aplicação de ureia. Não foram observados benefícios da aplicação isolada ou combinada de Ni e sacarose.
Palavras-chave: Glycine max L.; nutrição de plantas; adubação nitrogenada; micronutriente; urease.

Foliar fertilization of urea, nickel and sucrose in reproductive stage of soybean

ABSTRACT: The foliar application of N and Ni nutrients in the reproductive stage of soybean can bring benefits to the soybean crop. However, when using urea as a source for this practice, the occurrence of phytotoxicity in the leaves is common. This phytotoxicity can be reduced by adding Ni and sucrose to the spray solution. Thus, the present work aimed to evaluate the application of a solution with different urea concentrations, with and without the presence of Ni and sucrose. The experimental design used was in randomized blocks, in a 4x2x2 factorial scheme, with four replications. The treatments consisted of four urea concentrations (0, 5, 10 and 15% w/v), in the presence or absence of Ni (30 g ha-1 of Ni), with and without the addition of sucrose (1 mol L- 1), applied to the leaves at the beginning of the grain filling phase. The foliar application of urea proved to be viable only with the addition of sucrose to the spray solution. The addition of sucrose in the spray solution eliminates phytotoxicity in soybean plants caused by urea. No benefits were observed from the isolated or combined application of Ni and sucrose.
Keywords: Glycine max L.; plants nutrition; nitrogen fertilization; micronutrient; urease.
СТРАТЕГІЧНЕ ПЛАНУВАННЯ ДІЯЛЬНОСТІ В ТУРИСТИЧНІЙ ОРГАНІЗАЦІЇ
Authors: ТЮРІНА Ніла , КРАВЧИК Юрій , НАЗАРЧУК Тетяна 
Published: April 2023

Сучасному воєнному стану України притаманний занепад туристичної індустрії у більшості регіонів, згортання соціальних програм в цьому напрямі, втрата позитивних тенденцій і динаміки розвитку родинних та підтримуючих галузей, низькі конкурентоспроможність туристичних послуг і темпи економічного розвитку взагалі. Метою дослідження є визначення особливостей стратегічного планування в туристичних організаціях в сучасних умовах та виявлення факторів впливу на його формування.
Обґрунтовано послідовність вибору загальної стратегії розвитку туристичної організації на основі стратегічного планування. Досліджено склад та характер основних факторів впливу на процес стратегічного планування в туристичній організації:
- стан підтримуючих галузей і туристичної індустрії, позиція на ній туристичної організації, яка досліджується;
- цілі туристичної організації;
- інтереси і ставлення до бізнесу вищого керівництва;
- кваліфікація персоналу;
- фінансове забезпечення суб’єкта господарювання;
- зобов'язання туристичної організації щодо попередніх стратегій.
- ступінь залежності від факторів прямого та опосередкованого впливу зовнішнього середовища.
- фактор часу.
За результатами проведеного аналізу зроблено висновок, що організація ефективного механізму стратегічного планування допоможе не лише сформувати реальні цілі, а й забезпечити їх системне досягнення.
МАРКЕТИНГОВИЙ ПІДХІД ДО УПРАВЛІННЯ ФОРМУВАННЯМ ТУРИСТИЧНОГО ПРОДУКТУ
Authors: ЛУЩИК Марія , КАТКОВА Тетяна 
Published: April 2023

Сучасні умови господарювання вимагають від ринкових суб’єктів, які функціонують в туристичній галузі, постійного моніторингу зовнішніх та внутрішніх чинників, що здійснюють безпосередній вплив на їх діяльність. Автори статті стверджують, що розвиток ринку, а разом із тим, розвиток споживачів, шляхом підвищення їх вимог до туристичного продукту, вимагає від підприємств підвищення ефективності їх діяльності шляхом застосування інноваційних, комплексних підходів до управління процесом формування туристичного продукту.
Здійснений авторами статті аналіз сучасних літературних джерел показав недостатність обґрунтованих методичних інструментів до комплексного впровадження елементів маркетингу при управлінні процесом формування туристичного продукту маркетингового підходу. Таким чином, основне завдання дослідження полягає в тому, щоб надати суб’єктам господарювання, які здійснюють управління процесом формування туристичного продукту в умовах невизначеності, науково-обгрунтований, удосконалений аналітичний і комплексний інструмент для протистояння сучасним соціально-політичним та економічним викликам. В межах дослідження, авторами уточнено визначення управління процесом формування туристичного продукту при маркетинговому підході і пропонується його розуміти як планування комплексного обслуговування споживачів, організацію його просування на ринку туристичних продуктів за визначеною ціною, через оптимальні канали збуту та побудови ефективної комунікації із цільовими сегментами ринку.
В статті встановлено послідовність процесу формування туристичного продукту, що, за думкою авторів, охоплює визначення попиту та пропозиції на туристичному ринку; визначення функціональних особливостей продукту; генерація та відбір ідей; формування стратегії і тактики вироблення туристичного продукту; розроблення маркетингової стратегії реалізації продукту на туристичному ринку ринкове тестування; оцінювання економічної і соціальної ефективності; корегувальні дії, модифікація продукту; впровадження продукту на туристичний ринок. Авторами виявлено основні чинники, що формують цінність для споживачів туристичного продукту, а також, наведено порівняльну характеристику ключових ролей менеджменту та маркетингу в процесі формування туристичного продукту. Особливу увагу авторами зосереджено на розробці комплексу маркетингу в сфері туризму, який відрізняється від існуючих підходів, тим, що охоплює як внутрішні елементи, так і зовнішні.
Effects of dietary supplementation with fermented papaya on oxidative stress, symptoms, and microbiome in Parkinson's disease
Authors: Bolner Andrea , Bertoldi Loris , Benvenuto Giuseppe , Sattin Eleonora , Bosello Ottavio , Nordera Giampietro 
Published: April 2023

Background: Oxidative stress, understood as the alteration of the physiological equilibrium between the production of oxygen and nitrogen free radicals and their metabolic neutralization (redox imbalance), is a typical condition of several pathologies, including neurodegenerative ones.In Parkinson's disease (PD), oxidative phenomena typically interest the dopaminergic neurons of mesencephalic substantia nigra. Although it is unlikely that the redox imbalance represents the primary event of neurodegeneration, it is certain that it participates in cellular damage progression.Objectives: Interventions to prevent or reduce the extent of the oxidative stress in PD and the consequent oxidative damage are of crucial importance. With this study, we have evaluated the effects of prolonged treatment with fermented papaya preparation (FPP) on redox imbalance, clinical parameters, and intestinal microbiome of PD patients. Methods: For six months, one group of PD subjects were treated with FPP (n=19, verum) and another with placebo (n=20, control); then, in the following six months, the treatments were exchanged.Several blood biochemical and hematological parameters were measured at the start and at the end of treatments. Among them are some components of antioxidant barriers, free radicals (total peroxides) and biomarkers of oxidative damage on DNA and proteins. To check the effects of FPP treatment on intestinal bacterial flora, we also evaluated the modification of microbiome with regards to the relative amounts of different phyla, families, genera, and species. Furthermore, accurate evaluations were performed on motor symptoms and cognitive functions of patients with validated survey scales to check the effects of FPP treatment on clinical parameters and quality life. Results: Unlike the control group, the level of free radicals in the patients treated with FPP was not increased; the antioxidant barrier was strengthened and oxidative damages on proteins and especially on DNA were decreased. Even clinical features and quality life parameters of these patients have improved. Instead, the results of microbiome were inconclusive as changes resulted seemingly independent Ofelia the treatments.Conclusions: The study demonstrates that FPP may be a valuable aid in counteracting oxidative stress and improve the motor symptoms and cognitive functions in PD. This effect does not seem to depend on increased growth of a particular bacterial phylum because the microbioma composition does not change significantly following the treatment; it cannot be excluded, however, that FPP works otherwise by modifying not the quantity but rather the metabolism of some specific bacterial group or that it has effects on the integrity of the intestinal mucosa. Keywords: Papaya, oxidative stress, Parkinson’s disease, microbiome
Serological and molecular detection of parvovirus b19 in children with acute lymphoblastic leukemia.
Authors: Abdullah Iqbal M. , Abdullah Shatha F. , Al-Jadiry Mazin F. 
Published: April 2023

Background: Human parvovirus B19 (B19V) is the only human pathogenic parvovirus, It is highly erythrotropic and preferentially replicates in erythroid progenitor cells (EPCs). Recently the effects of B19 infection have been well studied in children with acute lymphoblastic leukemia (ALL).
Objective: To detect parvovirus B19 among children with ALL.
Methods: A cross sectional study involved forty five patients with ALL (21 patients were newly diagnosed ALL and 24 children who underwent chemotherapy) who were attending department of oncology in Children's Welfare Teaching Hospital in Baghdad Medical City between December 2012 and April 2013, compared to forty five of apparently healthy children as a control group, age and sex were matched. A serological and molecular detection of parvovirus B19 were done using enzyme linked immunosorbant assay (ELISA) and Real-time PCR.
Results: B19-IgM, IgG and DNA were detected in study cases as (15.6%, 40% and 13.3%) compared to control group (4.4%, 13 % and 0%) respectively. B19-IgG and B19-IgM were detected in newly diagnosed cases in (41.7% and 19.05%) as well as in (38.1% and 12. 5%) of cases on chemotherapy respectively, all cases with B19-DNA signals were underwent chemotherapy (25%) with mean viral load of (36x104 copies/ml).
Conclusion: children who suffering from ALL are at increased risk of B19 infection. Notable percentage of persistent B19 infection was recorded among children with ALL who are receiving ongoing treatment.
Synthesis of porous nanoparticles and their use as a cytotoxic agent.
Authors: Essa Hayder J. 
Published: April 2023

Background: In this study, a targeted drug delivery system has been developed based on nanoporous particles covered with cadmium sulfide and loaded with 5-flourouracil. The nanoparticles loaded drug exerts a cooperative antineoplastic activity.
Results: The development of nanoparticles loaded anticancer agent for possible application in targeted treatment of cancer where the drug release is triggered by externally applied UV irradiation. In addition, the treatment of cancer cells with drug loaded magnetic material leads to a decrease in viability of the cells due to the activity of cadmium nanoparticles. Upon exposure to low power UV light (365 nm) the loaded 5-flourouracil is released which induces additional decrease in viability of Cervical carcinoma cells HeLa.
Methods: Iron oxide nanoparticlers were synthesized and functionalized with cadmium and loaded with 5-flourouracil. Different techniques were used for characterization such as infrared (IR) and ultraviolet (UV) measurements. A cell culture test was done in order to investigate the effect of drug loaded on nanoparticles.
Conclusions: In summary, an anticancer drug delivery system based on nanoporous material loaded 5-fluorouracil has been developed. The cooperative anticancer effect of nanoparticles and loaded 5-flourouracil was observed.
Oxidative Stress and Total Antioxidant Capacity in Rheumatoid Arthritis.
Authors: Mahmood Halla G. , Ali Zeyan A. , Abdulhameed Raed A. , Hussein Ilham M. 
Published: April 2023

Back ground:-Rheumatoid arthritis (RA) is a systemic disease characterized by progressive, erosive and chronic poly arthritis, where cellular proliferation of the synoviocytes and neo-angiogenesis leads to formation of pannus which destroys the articular cartilage and the bone .
Objective :-to evaluate theOxidative Stress index( OSI )by measuring malondialdehide( MDA) and Total Antioxidant Capacity( TAC) in serum of RA patients in addition to uric acid and albumin and to investigate the alteration in these parameters compared to healthy individuals.
Patients and Methods :- twenty five patients with rheumatoid arithritis and twenty five apparently healthy subjects matched for age and weight have been included in this study,uricacid and Serum malondialdehyde were measured by enzymatic methods. serum total antioxidant capacity was measured according to Miller et al method.
Results :-The data obtained showed that the serum levels of Albumin, the total antioxidant capacity were significantly lower in patients with RA than in healthy controls.While the serum levels of MDA,uric acid were significantly higher in patients with RA than in healthy controls.
Conclusion:- there is acontribution of antioxidant to the pathogenesis of RA.
Analysis of position response characteristics of magnetic driven oil-free scroll compressor
Authors: Shi Ce , Sun Feng , Xu Fangchao , Jin Junjie , Tong Ling , Zhou Qing , Oka Koichi 
Published: April 2023

Traditional scroll compressors are difficult to achieve oil-free operation due to the presence of a high-friction anti-rotation mechanism. This paper proposes a magnetic drive oil-free scroll compressor to solve this problem. Firstly, the structure and principle of this scroll compressor are introduced. Then the finite element analysis of the electromagnetic system was conducted; the dynamics model of the magnetic scroll compressor operating in the uncompressed state was established. Finally, the PID control of the system is performed, and simulations and experiments are carried out. Experimental results: under the 0.05 mm step signal in the X direction, the position response time of the system is 0.1 s, and the angle response time of 0.001 rad is 0.2 s. The results show that the oil-free scroll compressor has good position control response characteristics.
Diagnostic Challenges of Neuromuscular Disorders after Whole Exome Sequencing
Authors: Chen Pin-Shiuan , Chao Chi-Chao , Tsai Li-Kai , Huang Hsin-Yi , Chien Yin-Hsiu , Huang Pei-Hsin , Hwu Wuh-Liang , Hsieh Sung-Tsang , Lee Ni-Chung , Hsueh Hsueh-Wen , Yang Chih-Chao 
Published: April 2023

Background: Whole-exome sequencing (WES) facilitates the diagnosis of hereditary neuromuscular disorders. To achieve an accurate diagnosis, physicians should interpret the genetic report carefully along with clinical information and examinations. We described our experience with (1) clinical validation in patients with variants found using WES and (2) a diagnostic approach for those with negative findings from WES. Methods: WES was performed on patients with the clinical impression of hereditary neuromuscular disorders. Information on clinical manifestations, neurological examination, electrodiagnostic studies, histopathology of muscle and nerve, and laboratory tests were collected. Results: Forty-one patients (Male/Female: 18/23, age of onset: 34.5±15.9) accepted WES and were categorized into four scenarios: (1) patients with a positive WES result, (2) patients with an inconclusive WES result but supporting clinical data, (3) negative findings from WES, but a final diagnosis after further work-up, and (4) undetermined etiology from WES and in further work-ups. The yield rate of the initial WES was 63.4% (26/41). Among these, seventeen patients had positive WES result, while the other nine patients had inconclusive WES result but supporting clinical data. Notably, in the fifteen patients with negative findings from WES, four patients (26.7%) achieved a diagnosis after further workup: tumor-induced osteomalacia, metabolic myopathy with pathogenic variants in mitochondrial DNA, microsatellite expansion disease, and vasculitis-related neuropathy. The etiologies remained undetermined in eleven patients (myopathy: 7, neuropathy: 4) after WES and further workup. Conclusions: It is essential to design genotype-guided molecular studies to correlate the identified variants with their clinical features. For patients who had negative findings from WES, acquired diseases, mitochondrial DNA disorders and microsatellite expansion diseases should be considered.
AI tools: A powerful new weapon to combat the misuse of statistics
Authors: Wilkinson Kate , Barrington Emily 
Published: April 2023

False information – whether mistakenly or intentionally distributed – threatens societies around the world, with dire consequences. When official statistics are misused or misrepresented, trust in this public good and the institutions that produce them are undermined. Two groups, fact checkers and statistical regulators, share common goals in combating this problem. Bolstering their work is a new offering of AI tools which help monitor vast volumes of media, identify important statements in public debate and inform users when statements they know to be wrong are repeated again. This article will cover the problem posed by false information, the common goals of fact checkers and statistical regulators, the development of AI tools and their impact.
Effects of virtual reality training in the postural control of children with Down syndrome: A case series
Authors: Leiton-Muñoz Andrea , Cartes-Velásquez Ricardo , Gatica-Rojas Valeska 
Published: April 2023

BACKGROUND: Children with Down syndrome (DS) may struggle adjusting their posture during gait or standing and tend to adapt slower to demanding motor tasks and environmental changes. The functionality in their daily activities is frequently diminished or they are slower, with poor postural control and balance as possible reasons. There is limited research on exercise programmes to improve postural control in children with DS. OBJECTIVE: To determine the effectivenes of an exercise programm with the Nintendo Wii Balance Board (NWBB) interface o postural control and functional balance of children with DS. METHODS: Participants were five children age 6–9 years belonging to the legal organization Espacio Down (in Talca, Chile), who underwen an exercise programm with the NWBB. The duration of the intervention wa 9 weeks, with two 25-minute sessions per week and a total intervention timeof 7.5 hours for each subject. Postural control pre-/postintervention was evaluated at a functional level with clinical tests: Timed Up and Go (TUG), One-Leg Standing (TOLS) and posturographic measures using centre of pressure (CoP) variables Descriptive statistics and the Wilcoxon test were applied, with [Formula: see text] 0.05 considered to be significant. RESULTS: Th NWBB programme showed a significant decrease in the CoP total velocity, mean velocity and displacements in themediolateral and anteroposterior directions ([Formula: see text] 0.021) for the closed-eyes condition and a decrease in the time of the TUG test ([Formula: see text] 0.021). CONCLUSIONS: This pilot study provides initial evidence for the effectiveness of the NWBB programme in children with DS. A 9-week NWBB programme improves the postural control and functional balanceof children with DS.