bluuebunny/crossref_metadata_2025_split huggingface dataset:
CuONPs/MWCNTs/carbon paste modified electrode for determination of tramadol: theoretical and experimental investigation
Authors: Razavi Razieh , Amiri Mahnaz , Divsalar Kouros , Foroumadi Alireza 
Published: May 2023

AbstractA practical technique was applied to fabricate CuO nanostructures for use as the electrocatalyst. The green synthesis of cupric oxide nanoparticles (CuO NPs) via co-precipitation is described in this paper using an aqueous extract of Origanum majorana as both reductant and stabilizer, accompanied by characterization via XRD, SEM, and FTIR. The XRD pattern revealed no impurities, whereas SEM revealed low agglomerated spherical particles. CuO nanoparticles and multi wall carbon nanotubes (MWCNTs) have been used to create a modified carbon paste electrode. Voltammetric methods were used to analyze Tramadol using CuONPs/MWCNT as a working electrode. The produced nanocomposite showed high selectivity for Tramadol analysis with peak potentials of ~ 230 mV and ~ 700 mV and Excellent linear calibration curves for Tramadol ranging from 0.08 to 500.0 µM with a correlation coefficient of 0.9997 and detection limits of 0.025. Also, the CuO NPs/MWCNT/CPE sensor shows an an appreciable sensitivity of 0.0773 μA/μM to tramadol. For the first time the B3LYP/LanL2DZ, quantum method was used to compute DFT to determine nanocomposites' connected energy and bandgap energy. Eventually, CuO NPs/CNT was shown to be effective in detecting Tramadol in actual samples, with a recovery rate ranging from 96 to 104.3%.
Design and introduction of quaternary ammonium hydroxide‐functionalized graphene oxide quantum dots as a pseudo-homogeneous catalyst for epoxidation of α,β-unsaturated ketones
Authors: Mohammed Mohammed Salim , Targhan Homa , Bahrami Kiumars 
Published: May 2023

AbstractIn present work, design and synthesis of a novel pseudo-homogeneous catalyst is described. For this purpose, amine-functionalized graphene oxide quantum dots (N-GOQDs) were prepared from graphene oxide (GO) by a facile one-step oxidative fragmentation approach. The prepared N-GOQDs were then modified with quaternary ammonium hydroxide groups. Various characterization techniques clearly revealed that the quaternary ammonium hydroxide‐functionalized GOQDs (N-GOQDs/OH−) have been successfully synthesized. TEM image revealed that the GOQDs particles are almost regularly spherical in shape and mono-dispersed with particle sizes < 10 nm. The efficiency of the synthesized N-GOQDs/OH− as a pseudo-homogeneous catalyst in epoxidation of α,β-unsaturated ketones in the presence of aqueous H2O2 as an oxidant at room temperature was investigated. The corresponding epoxide products were obtained in good to high yields. This procedure has the advantages of a green oxidant, high yields, involvement of non-toxic reagents and reusability of the catalyst without discernible loss in activity.
Multi-sample/multi-nucleus parallel polarization and monitoring enabled by a fluid path technology compatible cryogenic probe for dissolution dynamic nuclear polarization
Authors: Lê Thanh Phong , Hyacinthe Jean-Noël , Capozzi Andrea 
Published: May 2023

AbstractLow throughput is one of dissolution Dynamic Nuclear Polarization (dDNP) main shortcomings. Especially for clinical and preclinical applications, where direct 13C nuclei polarization is usually pursued, it takes hours to generate one single hyperpolarized (HP) sample. Being able to hyperpolarize more samples at once represents a clear advantage and can expand the range and complexity of the applications. In this work, we present the design and performance of a highly versatile and customizable dDNP cryogenic probe, herein adapted to a 5 T “wet” preclinical polarizer, that can accommodate up to three samples at once and, most importantly, it is capable of monitoring the solid-state spin dynamics of each sample separately, regardless of the kind of radical used and the nuclear species of interest. Within 30 min, the system was able to dispense three HP solutions with high repeatability across the channels (30.0 ± 1.2% carbon polarization for [1-13C]pyruvic acid doped with trityl radical). Moreover, we tested multi-nucleus NMR capability by polarizing and monitoring simultaneously 13C, 1H and 129Xe. Finally, we implemented [1-13C]lactate/[1-13C]pyruvate polarization and back-to-back dissolution and injection in a healthy mouse model to perform multiple-substrate HP Magnetic Resonance Spectroscopy (MRS) at 14.1 T.
Ethiopian orthodox fasting is associated with weight reduction and body composition changes among healthy adults: a prospective cohort study
Authors: Michael Alemayehu , Baye Kaleab 
Published: May 2023

AbstractThe Ethiopian Orthodox Christian (EOC) fasts, although adopted for religious purposes, combines aspects of energy restriction, time-restricted feeding, and a vegan dietary pattern, all of which have been independently associated with weight loss and healthier body composition. However, combined effect of these practices as part of EOC fast remains unknown. This longitudinal study design evaluated the effect of EOC fasting on body weight and body composition. Information on socio-demographic characteristics, physical activity level, and fasting regimen followed was captured through an interviewer-administered questionnaire. Weight and body composition measurements were taken before and at the end of major fasting seasons. Body composition parameters were measured by bioelectrical impedance (BIA), Tanita® BC-418®, Japan). Significant changes in body weight and body composition were observed for both fasts. Significant decreases in body weight (14/44 day fast: − 0.45; P = 0.004/− 0.65; P = 0.004), FFM (− 0.82; P = 0.002/− 0.41; P < 0.0001), and trunk fat mass (− 0.68; P < 0.0001/− 0.82; P < 0.0001) were observed after adjusting for covariates including age, sex, and physical activity. The EOC fasting regimen leads to significant reductions of body weight and compositions. Longer fasting duration led to much higher effects in body weight and body composition and may be non-pharmacological strategy in prevention or treatment of chronic diseases.
Integrative Mendelian randomization reveals the soluble receptor for advanced glycation end products as protective in relation to rheumatoid arthritis
Authors: Lee Gha Young , Yao Chen , Hwang Shih-Jen , Ma Jiantao , Joehanes Roby , Lee Dong Heon , Ellison R. Curtis , Moore Lynn L. , Liu Chunyu , Levy Daniel 
Published: May 2023

AbstractRheumatoid arthritis (RA) is a risk factor for atherosclerotic cardiovascular diseases (CVD). Given the critical roles of the immune system and inflammatory signals in the pathogenesis of CVD, we hypothesized that interrogation of CVD-related proteins using integrative genomics might provide new insights into the pathophysiology of RA. We utilized two-sample Mendelian randomization (MR) for causal inference between circulating protein levels and RA by incorporating genetic variants, followed by colocalization to characterize the causal associations. Genetic variants from three sources were obtained: those associated with 71 CVD-related proteins measured in nearly 7000 Framingham Heart Study participants, a published genome-wide association study (GWAS) of RA (19 234 cases, 61 565 controls), and GWAS of rheumatoid factor (RF) levels from the UK Biobank (n = 30 565). We identified the soluble receptor for advanced glycation end products (sRAGE), a critical inflammatory pathway protein, as putatively causal and protective for both RA (odds ratio per 1-standard deviation increment in inverse-rank normalized sRAGE level = 0.364; 95% confidence interval 0.342–0.385; P = 6.40 × 10–241) and RF levels (β [change in RF level per sRAGE increment] = − 1.318; SE = 0.434; P = 0.002). Using an integrative genomic approach, we highlight the AGER/RAGE axis as a putatively causal and promising therapeutic target for RA.
Research on spatial and temporal differences of carbon emissions and influencing factors in eight economic regions of China based on LMDI model
Authors: Jiang Pan , Gong Xiujuan , Yang Yirui , Tang Kai , Zhao Yuting , Liu Shu , Liu Liang 
Published: May 2023

AbstractWith the gradual increase of international willingness to reach the carbon peak and carbon neutrality, this paper decomposes the influencing factors of China’s carbon emission changes from 2008 to 2019 using the Logarithmic Mean Divisia Index model (LMDI), and analyzes the contribution amount and rate of each influencing factor. The results found that: for the whole country, the cumulative growth of carbon emissions during the study period is about 416,484.47 (104 tons), among which the economic growth effect plays a major role in promoting, with a cumulative contribution rate of 284.16%; The increase in regulation intensity and the optimization of industrial structure, however, suppress carbon emissions well, with a cumulative contribution rate of about – 199.21% and − 64.75%, respectively, during the study period. For economic regions, the cumulative influence direction of each driver is the same as that of the whole country, while the population size effect in the northeast economic region and the regulation input effect in the eastern coastal economic region act in the opposite direction from other economic regions, and the carbon emission reduction direction of the energy intensity effect varies from one economic region to another. Accordingly, this paper proposes policy recommendations to enhance regulatory intensity, optimize industrial and energy consumption structure, implement localized emission reduction strategies, and promote synergistic emission reduction in economic zones.
Deep learning application for the classification of Alzheimer’s disease using 18F-flortaucipir (AV-1451) tau positron emission tomography
Authors: Park Sang Won , Yeo Na Young , Kim Yeshin , Byeon Gihwan , Jang Jae-Won 
Published: May 2023

AbstractThe positron emission tomography (PET) with 18F-flortaucipir can distinguish individuals with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) from cognitively unimpaired (CU) individuals. This study aimed to evaluate the utility of 18F-flortaucipir-PET images and multimodal data integration in the differentiation of CU from MCI or AD through DL. We used cross-sectional data (18F-flortaucipir-PET images, demographic and neuropsychological score) from the ADNI. All data for subjects (138 CU, 75 MCI, 63 AD) were acquired at baseline. The 2D convolutional neural network (CNN)-long short-term memory (LSTM) and 3D CNN were conducted. Multimodal learning was conducted by adding the clinical data with imaging data. Transfer learning was performed for classification between CU and MCI. The AUC for AD classification from CU was 0.964 and 0.947 in 2D CNN-LSTM and multimodal learning. The AUC of 3D CNN showed 0.947, and 0.976 in multimodal learning. The AUC for MCI classification from CU had 0.840 and 0.923 in 2D CNN-LSTM and multimodal learning. The AUC of 3D CNN showed 0.845, and 0.850 in multimodal learning. The 18F-flortaucipir PET is effective for the classification of AD stage. Furthermore, the effect of combination images with clinical data increased the performance of AD classification.
Spectroscopies chiroptiques. Quand la lumière explore l’asymétrie de la matière
Authors: Pons Bernard , Nahon Laurent 
Published: May 2023

L’interaction de la lumière avec la matière fournit des informations sur sa chiralité quand la lumière est elle-même chirale, telle une onde polarisée circulairement droite ou gauche. C’est l’objet des spectroscopies chiroptiques, qui sont présentées ici et qui connaissent un essor spectaculaire depuis une vingtaine d’années.
Dans cet article, on s’intéresse tout particulièrement à l’asymétrie observée dans l’angle d’émission des électrons éjectés par une molécule chirale après ionisation par une onde polarisée circulairement, appelée dichroïsme circulaire de photoélectrons.
Vortex optiques en interaction avec des atomes
Authors: Pruvost Laurence , Ruchon Thierry 
Published: May 2023

Un vortex optique est un faisceau laser dont le front d’onde est hélicoïdal. Il est donc chiral, d’hélicité gauche ou droite selon le sens de l’hélice. En plus du moment angulaire de spin qui correspond à la polarisation, les photons possèdent aussi un moment angulaire orbital (OAM) qui est quantifié et caractérise l'hélicité du vortex.
L’interaction non linéaire de vortex optiques avec des atomes conduit à l’échange d’OAM avec l‘ensemble atomique et la génération de nouveaux vortex. Les propriétés quantiques de ces vortex sont une ressource exploitable dans le cadre des technologies quantiques comme le stockage et le codage de l’information.
Análise Crítica do PEPAC na perspetiva do setor florestal
Authors: Viegas Miguel , Carneiro Susana 
Published: May 2023

O presente artigo parte da análise da repartição geográfica dos apoios da PAC, identificando uma profunda assimetria que penaliza fortemente os territórios considerados como mais vulneráveis em matéria de desenvolvimento socioeconómico e de vulnerabilidade aos incêndios. A partir destes dados, os autores elaboram uma análise crítica do processo de elaboração do PEPAC, incluindo as recomendações da Comissão Europeia.
De acordo com as características próprias do território português, incluindo a sua estrutura fundiária, os autores consideram que o atual PEPAC, seja pelos montantes envolvidos seja pelo desenho das medidas de apoio, não responde às necessidades da floresta portuguesa e muito dificilmente irá inverter a sua tendência de declínio e empobrecimento. O artigo termina com um conjunto de sugestões para aumentar a capacidade de absorção de apoios nos territórios vulneráveis.
Intellectual Property in Facial Plastic and Reconstructive Surgery: The Importance and Process of Obtaining Intellectual Property Rights
Authors: Razavi Christopher R. , Byrne Patrick J. 
Published: May 2023

AbstractUnderstanding the purpose and process of obtaining intellectual property rights (IPR) is fundamental to health care innovation. Facial plastic and reconstructive surgeons are natural innovators; however, knowledge deficit in this space may hinder the ability to move ideas from the “bench to bedside.” Here we provide an overview of IPR, outlining the steps necessary to obtain intellectual property protection in an academic setting while highlighting recent U.S. Food and Drug Administration (FDA) approvals pertaining to facial plastic and reconstructive surgery.
The Effect of Various Training Variables on Developing Muscle
Strength in Velocity-based Training: A Systematic Review and
Meta-analysis
Authors: Zhang Xing , Li Hansen , Feng Siyuan , Su Songpeng 
Published: May 2023

AbstractVelocity-based training is an advanced auto-regulation method that uses objective
indices to dynamically regulate training loads. However, it is unclear currently
how to maximize muscle strength with appropriate velocity-based training
settings. To fill this gap, we conducted a series of dose-response and subgroup
meta-analyses to check the effects of training variables/parameters,
such as intensity, velocity loss, set, inter-set rest intervals, frequency,
period, and program, on muscle strength in velocity-based training. A systematic
literature search was performed to identify studies via PubMed, Web of Science,
Embase, EBSCO, and Cochrane. One repetition maximum was selected as the outcome
to indicate muscle strength. Eventually, twenty-seven studies with 693 trained
individuals were included in the analysis. We found that the velocity loss of 15
to 30%, the intensity of 70 to 80%1RM, the set of 3 to 5 per
session, the inter-set rest interval of 2 to 4 min, and the period of 7
to 12 weeks could be appropriate settings for developing muscle strength. Three
periodical programming models in velocity-based training, including linear
programming, undulating programming, and constant programming, were effective
for developing muscle strength. Besides, changing periodical programming models
around every 9 weeks may help to avoid a training plateau in strength
adaption.
Changing approaches to green infrastructure design: from modernism to the future: Warsaw case study
Authors: Solarek Krystyna , Domaradzka Anna , Zdunek-Wielgołaska Justyna 
Published: May 2023

AbstractInternational modernism has brought new solutions to urban greenery, primarily aimed at improving the living conditions of the inhabitants. Currently, much more is expected of green areas, and at the same time, various impacts influence their modifications. The article focusses on changing approaches to the issue of green wedges design resulting from the socio-political transformation and the changes in approaches to city planning priorities. We selected Warsaw for detailed research, where the evolution of this approach can be clearly observed. The study showed the changes in the size, layout and function of one of the most important green areas and residents’ expectations. The formulated conclusions and threads may be helpful in spatial policy, spatial planning and urban design in various cities with an open areas structure similar to Warsaw.
Technology, culture and critical theory: an interview with Andrew Feenberg
Authors: Feenberg Andrew , McCarthy Daniel R. 
Published: May 2023

AbstractAndrew Feenberg is a pioneer in the development of the philosophy of technology. Before his retirement, he was the Canada Research Chair in Philosophy of Technology in the School of Communication, Simon Fraser University, where he also directed the Applied Communication and Technology Laboratory (ACTL). He is the author or editor of thirteen books on Critical Theory, Western Marxism, and the philosophy of technology, including Lukács, Marx, and the Sources of Critical Theory (1981), Critical Theory of Technology (1991), Technology and the Politics of Knowledge (ed with Alastair Hannay) (1995), Questioning Technology (1999), (Re)Inventing the Internet: Critical Case Studies (ed with Norm Friesen) (2012) and Technosystem: The Social Life of Reason (2017).
Discontinuous Plurality in Chilean Spanish
Authors: Christensen Rachel 
Published: May 2023

Abstract
This work proposes an analysis to account for a
discontinuous construction in Chilean Spanish resulting in plural
inflectional morphology on the corresponding verb. In contrast with
a plural DP or a conjunction of two singular DPs, this construction
combines a bundle of Φ features, licensed by an Operator Phrase, and
a DP that is introduced by a with-phrase. This
study provides the first analysis of this agreement pattern in
Chilean Spanish and introduces new empirical data that distinguishes
Chilean from other Spanish varieties. Research addresses the
distinctions of this Chilean construction and expands on previous
theories of plural agreement, i.e., Plural Pronoun Construction and
Comitative Coordination (Vassilieva, 2005; Camacho, 1996) to account for a wider array of
linguistic variety.
Exploring future-in-the-past variation in Seville and
Caracas
Authors: Swain Angela , Berríos Juan , Kanwit Matthew 
Published: May 2023

Abstract
Research on Spanish future-time expression has
revealed a diachronic rise for the periphrastic future. However,
future-in-the-past expression remains understudied. Two common
variants are the periphrastic future in the imperfect (e.g.,
iba a bailar ‘I was going to dance’) and the
conditional (e.g., bailaría ‘I would dance’). Our
study is unique in assessing future-in-the-past expression through a
controlled task able to elicit greater token counts and its
consideration of data beyond Spain. In this exploratory study, we
analyzed residents of Seville, Spain and Caracas, Venezuela via a
written contextualized task, examining linguistic predictors
(temporal distance, polarity, and verb type). Results echo research
on future-time expression: the periphrastic form has gained traction
and has developed through analogous predictors. Moreover, findings
reveal notable cross-variety similarity.
Civics, ideology, and Spanish in Kansas
Authors: Colcher Drew 
Published: May 2023

Abstract
Research on Spanish as a Heritage Language (HL)
describes how integrative ideologies emphasizing
cultural/linguistic identity motivate HL students more than
instrumental ideologies of Spanish as a
professional resource. Less explored are civic
ideologies of serving communities through bilingualism. Studies of
service-learning in language classes highlight the importance of
civics, but do not analyze civic motivations as part of
service-learning’s efficacy. To further ground pedagogical theory in
community norms, I explore ideologies/motivations among heritage
Spanish speakers outside of HL programs. The analysis suggests
participants variably associate civic, instrumental, and integrative
ideologies with their language capabilities, simultaneously
positioning themselves as variably integrated within the community.
These associations ask us to rethink common conceptions of
motivation.
L2 sociolinguistic perception of stylistic variation
Authors: Michalski Ian 
Published: May 2023

Abstract
There is growing interest in using experimental
perception tasks to study the sociolinguistic competence of second
language learners. Previous studies on L2 attitudes and perception
have largely focused on single linguistic variants presented in
guises with limited social context. This chapter reports on a study
that explores the L2 sociolinguistic perception of stylistic
variation in Spanish. L2 learner participants
(n = 108) completed a matched-guise task in which
they evaluated digitally manipulated audio guises containing the
variable reduction of [paɾa] to [pa] and the variable weakening of
coda /s/. The guises were rated according to social attractiveness
and social superiority. Linear mixed-effects modeling selected
speaker voice, linguistic variables, and experience with linguistic
courses as significant factors in predicting the attitudinal
responses.