bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Disseminated Encephalomyelitis and Acute Encephalitis Following
Vaccination Against SARS-CoV-2: Two Case Reports and Review of
Literature
Authors: Weidauer Stefan , Zeitz Anne , Tafreshi Mona , Hattingen Elke , Arendt Christophe 
Published: March 2023

AbstractThe spectrum of severe neurological complications following COVID-19 vaccination
includes cerebrovascular events, inflammatory diseases of the CNS, cranial and
peripheral nerve involvement and muscle affections. Post-vaccinal acute
disseminated encephalomyelitis (ADEM) and acute encephalitis are rare. We report
on a patient suffering from acute encephalitis and another with post-vaccinal
monophasic ADEM. Beside imaging features typical for acute autoimmune associated
inflammation, cranial MRI disclosed also transient haemorrhagic signal
alterations in some cerebral lesions. To our best knowledge, this has not been
mentioned before in literature. Competing causes were excluded by extensive
laboratory investigations including serial CSF analysis. In line with the
literature, repeated iv high-dosage corticosteroid therapy resulted in
impressive improvement of neurological symptoms in both patients.
Blue-Blood Pig Thorax Model Increases Residents' Confidence in Internal Mammary Dissection
Authors: Gunderson Kirsten A. , Zeng Weifeng , Nkana Zeeda H. , Matabele Wood Kasey Leigh , Lyon Sarah M. , Albano Nicholas J. , Poore Samuel O. 
Published: March 2023

Abstract
Background Preparation of the recipient vessels is a crucial step in autologous breast reconstruction, with limited opportunity for resident training intraoperatively. The Blue-Blood–infused porcine chest wall—a cadaveric pig thorax embedded in a mannequin shell, connected to a saline perfusion system—is a novel, cost-effective ($55) simulator of internal mammary artery (IMA) dissection and anastomosis intended to improve resident's comfort, safety, and expertise with all steps of this procedure. The purpose of this study was to assess the effect of the use of this chest wall model on resident's confidence in performing dissection and anastomosis of the IMA, as well as obtain resident's and faculty's perspectives on model realism and utility.
Methods Plastic surgery residents and microsurgery faculty at the University of Wisconsin were invited to participate. One expert microsurgeon led individual training sessions and performed as the microsurgical assistant. Participants anonymously completed surveys prior to and immediately following their training session to assess their change in confidence performing the procedure, as well as their perception of model realism and utility as a formal microsurgical training tool on a five-point scale.
Results Every participant saw improvement in confidence after their training session in a minimum of one of seven key procedural steps identified. Of participants who had experience with this procedure in humans, the majority rated model anatomy and performance of key procedural steps as “very” or “extremely” realistic as compared with humans. 100% of participants believed practice with this model would improve residents' ability to perform this operation in the operating room and 100% of participants would recommend this model be incorporated into the microsurgical training curriculum.
Conclusion The Blue-Blood porcine chest wall simulator increases trainee confidence in performing key steps of IMA dissection and anastomosis and is perceived as valuable to residents and faculty alike.
Successful Sirolimus Treatment for Recurrent Pericardial Effusion in a Large Cervicomediastinal Provisionally Unclassified Vascular Anomaly: A Case Report
Authors: Moreno-Alfonso Julio César , San Basilio Berenguer María , Sarmiento Caldas María del Carmen , González Cayón Jesús , de la Puente Santiago , Triana Paloma , López-Gutiérrez Juan Carlos 
Published: March 2023

AbstractProvisionally unclassified vascular anomalies (PUVA) are a group of diseases with unique characteristics that make them unclassifiable within vascular tumors or malformations. We describe a PUVA as the cause of recurrent pericardial effusion and its response to sirolimus. A 6-year-old girl was referred with a cervicothoracic vascular anomaly, a violaceous, and irregular lesion in the neck and upper chest, diagnosed as “hemangioma”. She had pericardial effusion at the neonatal age that required pericardiocentesis, propranolol, and corticosteroids. She remained stable for 5 years, when she presented with a severe pericardial effusion. A magnetic resonance visualized a diffuse vascular image in the cervical and thoracic region with mediastinal extension. The pathological study showed a vascular proliferation in the dermis and hypodermis with positive staining for Wilms' Tumor 1 Protein (WT1) and negative for Glut-1. Genetic testing found a variant in GNA14, for which the diagnosis of PUVA was established. When a pericardial drain was placed without response, treatment with sirolimus was started with resolution of the effusion. Sixteen months later, the malformation is stable and there has been no recurrence of pericardial effusion. In a significant group of patients, definitive diagnosis is not possible despite pathological and genetic analysis. Mammalian target of rapamycin inhibitors may become a therapeutic option if symptoms are severe enough, with a low rate of reported side effects.
Predictive Ability of Conventional and Combined Apgar Scores versus Neonatal Resuscitation and Adaptation Score in Early Neonatal Assessment
Authors: Midan Dina A. , El-Gendy Fady M. , Bahbah Wael A. , Alamah Hadeer Y. , Elzayat Rania S. 
Published: March 2023

Objective The aim of this study was to assess the Neonatal Resuscitation and Adaptation Score (NRAS) value compared with the conventional and combined Apgar scores in predicting neonatal morbidity and mortality.
Study Design A prospective cohort study was conducted on 289 neonates delivered at the Menoufia University Hospital. Trained physicians measured conventional Apgar score, combined Apgar score, and NRAS for the neonates at 1 and 5 minutes after delivery in the delivery room. Admitted neonates were followed during their stay to detect any adverse outcomes.
Results Morbidities such as the need for neonatal intensive care unit admission, mechanical ventilation, surfactant and inotropes administration, need for extensive phototherapy, intravenous immunoglobulin or exchange transfusion, anemia, metabolic acidosis, abnormal liver and kidney function tests, coagulopathies, hypoglycemia, development of seizures in the first 72 hours of life, and positive changes in cranial ultrasound were significantly higher in neonates who lie within low or moderate NRAS than conventional and combined Apgar scores (p < 0.05). As predictors of mortality, the low and moderate values of the NRAS had higher positive predictive values at 1 (73.91 and 30.61%) and 5 minutes (88.89 and 50.94%) than the conventional Apgar scores at 1 (49.18 and 20.53%), 5 minutes (81.25 and 41.27%) and the combined Apgar scores at 1 (35.63 and 12.45%) and 5 minutes (53.1 and 41.33%).
Conclusion Our study suggests that the NRAS is better than conventional and combined Apgar scores in predicting neonatal morbidity and mortality. Furthermore, a depressed 5-minute NRAS is more predictive of mortality than 1-minute score.
Key Points
Antibodies against Noncatalytic B Subunit of Factor XIII Inhibit Activation of Factor XIII and Fibrin Crosslinking
Authors: Souri Masayoshi , Yokoyama Chikako , Osaki Tsukasa , Ichinose Akitada 
Published: March 2023

Background Coagulation factor XIII (FXIII) is a proenzyme of plasma transglutaminase. It comprises two catalytic A subunits (FXIII-A) and two carrier B subunits (FXIII-B). We previously reported that alloantibodies against FXIII-B could promote FXIII clearance in a patient with congenital FXIII-B deficiency who had received infusions of plasma-derived human FXIII (A2B2 heterotetramer).
Objectives We aimed to investigate whether anti-FXIII-B antibodies affect the catalytic function of FXIII.
Methods FXIII activation and fibrin crosslinking were examined in the presence of patient plasma, isolated patient IgG, or rat anti-FXIII-B monoclonal antibodies.
Results Alloantibody levels were increased by repeated infusions of plasma-derived A2B2 heterotetramer, which enhanced binding to the functionally important FXIII-B sushi domains. The patient plasma strongly inhibited cleavage of the FXIII-A activation peptide, amine incorporation, and fibrin crosslinking in normal plasma. Furthermore, anti-FXIII-B alloantibodies blocked the formation of the complex of FXIII-B with FXIII-A, and fibrinogen. Rat monoclonal antibodies against the 10th sushi domain of FXIII-B inhibited the incorporation of FXIII-B to fibrin, FXIII activation (i.e., cleavage of FXIII-A activation peptide), and ultimately fibrin crosslinking in normal plasma, independent of their effect on heterotetramer assembly with FXIII-A. Alloantibody binding to the A2B2 heterotetramer blocked the access of thrombin to the FXIII-A cleavage site, as indicated by the reaction of the alloantibodies to the A2B2 heterotetramer and FXIII-B, but not to FXIII-A.
Conclusion Anti-FXIII-B antibodies binding to the A2B2 heterotetramer and FXIII-B inhibited FXIII activation and its crosslinking function despite being directed against its noncatalytic subunit (FXIII-B).
Association of Selected Fitness Variables with Perceived Performance Levels in Lawn Tennis Players
Authors: Manchanda Sukriti , Saxena Shobhit , Sharma Pooja , Rizvi Moattar Raza , Sharma Ankita , Ahmad Irshad , Kachanathu Shaji John 
Published: March 2023

Abstract
Objectives Lawn tennis is an explosive sport that involves various fitness parameters such as explosive strength, endurance, power, and agility. Improved physical fitness leads to superior athletic performance. The coach's perception is contingent upon his perception of the player at the time the athlete is comparing himself to the coach. Thus, this study aimed to determine the association between chosen fitness factors and perceived performance by coach in lawn tennis players. Thus, the study aims to detect the relationship between different fitness variables and perceived level of performance in lawn tennis player.
Materials and Methods Fifty-two lawn tennis players from two sports academies were measured for various parameters of fitness and perceived performance level as rated by the coach.
Statistical Analysis The association between selected fitness metrics and perceived performance in lawn tennis players was investigated using Pearson's correlation test. Furthermore, the data were analyzed with paired t-test for male and female group, and ANOVA was used to analyze the difference between the levels of performance.
Results Fatigue index, closed kinetic chain upper extremity stability (CKCUEST) test, and peak power and energy expenditure taken by metabolic equivalent (MET) calculation was found to be statistically different between males and females. While comparing BMI with the peak power, there was a weak positive correlation for males, while for female there was no correlation. Metabolic equivalent, energy expenditure, and peak power were positively correlated with the level of performance; however, fatigue index and level of performance had a negative nonsignificant correlation.
Conclusion Peak power, fatigue index, energy expenditure, and BMI were found to be associated in males, but not in females. Peak power and energy expenditure were connected to performance in both genders.
Knowledge and Practices Regarding Oral Hygiene, Cariogenic Diet Intake, and Dental Check-Ups Among Registered Nurses in Nigeria: A Pilot Study
Authors: Kanmodi Kehinde Kazeem , Amoo Babatunde Abiodun , Nwafor Jacob Njideka , Nnyanzi Lawrence Achilles , Ogbeide Mike Eghosa , Hundeji Abdullahi Adamu , Adetunji Charles Oluwaseun 
Published: March 2023

AbstractObjectives To investigate the knowledge and practices of registered nurses in Nigeria concerning oral hygiene, cariogenic diets, and dental check-ups through a pilot study.Methods This study was an online survey of 129 registered nurses in Nigeria. Data were collected via the WhatsApp social media using an electronic questionnaire (Google form). Data analysis was done using the SPSS version 26 software (IBM Corp, New York, USA).Results The response and completeness rates of this pilot study were 41.7% (129/311) and 96.9% 9125/129), respectively. The majority (62.2%) of the respondents were females. The majority (89.1%) had average/above average score on basic oral health knowledge; however, there was no significant relationship between their level of basic oral health knowledge and their sociodemographic characteristics (p > 0.05). The majority (66.7%) of the respondents brushed twice daily, 86.8% used a fluoridated toothpaste, and 60.5% changed their toothbrush every 3 months. Furthermore, more than half (55.8%) consumed sugary snack/drink on daily basis, while 55.0% rinsed their mouth with water immediately after taking sugary snack, and only 55.8% did floss their teeth. Among those who flossed their teeth, only 37.5% did it once daily. It is also striking that 26.4% of the respondents had never visited a dentist for a dental check-up.Conclusion Study findings showed a high level of basic oral health knowledge and a lower level of appropriate oral self-care practices among nurses in Nigeria. However, there is a need for a nationally representative study of nurses in Nigeria to further establish these findings.
Misidentification of Plasmodium Species by Cross-Reacting Primers and Cerebral Malaria Caused by Plasmodium vivax
Authors: Rai Anoopkrishna , Pinto Deepak Sebastian , Rai Praveen , Teerthanath Srinivas , Karunasagar Indrani , Adiga Rama 
Published: March 2023

Abstract
Introduction The clinical presentation of a case as cerebral malaria with molecular identification confirming it as Plasmodium vivax underlines the importance of using molecular tools to identify the species and type of malaria. The possibility of the relationship between the complication observed during clinical diagnosis and the multifactorial molecular changes could likely be the reason for terming it cerebral malaria.
Methods We report four cases analyzed using the quantitative buffy coat technique followed by classical Giemsa stained thick-film microscopy, and nested polymerase chain reaction for the genus-specific region of Plasmodium targeting 18S rDNA followed by species-specific identification with a different set of primers and products confirmation with sequencing.
Results Primers targeting P. knowlesi generated the expected product size of 153 base pairs that, upon sequencing, matched with the P. vivax sequence reflecting the relatedness of the species. Likewise, primers targeting P. ovale generated a 456 product whose sequence matched the P. vivax sequence.
Conclusion Infection with P. vivax can potentially cause cerebral malaria, and P. vivax can cause severe malaria complications alone or mixed with other species and can show cerebral malaria signs, which are typically associated with P. falciparum infections. The sequence relatedness reflects the genome similarity between P. knowlesi and P. ovale with P. vivax. The need to reconfirm with an additional set of newly reported primers is mandatory.
Socioeconomic Risk Factors for Preterm Birth in Manipur, Northeast India: A Community-Based Study
Authors: Devi Thangjam Chitralekha , Singh Huidrom Suraj 
Published: March 2023

AbstractBackground Preterm birth (PTB) is one of the world's leading health concerns, affecting both the mother and the children. This study was undertaken to determine the prevalence and socioeconomic factors associated with PTB among the Meitei women of Manipur.Materials and Methods A community-based cross-sectional study was conducted in postpartum Meitei women of Manipur. Participants were 126 postpartum women that gave birth to a singleton live-born infant and were classified as women giving birth before 37 weeks of gestation (PTB) and women giving birth at ≥37 weeks (term). Data were compared using univariate analysis, and the association of socioeconomic factors with PTB was determined through multivariate logistic regression using Statistical Package for Social Sciences 25 version software program, and statistical significance was taken at a p-value < 0.05.Results The overall prevalence of PTB is 23.01%, of which 13.79% are of extremely preterm. This study revealed a significant association of PTB with mother's occupation (adjusted odds ratio [AOR] = 4.46, 95% confidence interval [CI]: 1.40–14.26, p = 0.012), tobacco consumption during pregnancy (AOR = 2.90, 95% CI: 1.01–8.33, p = 0.048), having family history of PTB (AOR = 3.14, 95% CI: 1.09–9.04, p = 0.034), and early age at menarche (AOR = 4.26, 95% CI: 1.49–12.12, p = 0.007).Conclusion The study highlights the high prevalence of PTB and its association with various socioeconomic factors. Such community-specific studies should be performed to understand the differential risk factors of PTB to control premature death in under 5 years children and to promote women's reproductive health.
The Outcomes of Treatment in Infants with Short Bowel Syndrome
Authors: Tran Quynh Anh , Ngo Tam Thi , Nguyen Tran Thi Ngoc , Le Son Thanh , Ho Thanh Chi , Thai Thao Khac , Tran Hung 
Published: March 2023

Abstract
Objective We reviewed 50 infant cases with short bowel syndrome (SBS) to examine the treatment outcome of SBS management in a tertiary hospital in Vietnam.
Material and Methods A case series was performed at the National Children's Hospital, Hanoi, Vietnam. A total of 50 cases with SBS were reviewed. Clinical and laboratory characteristics before and after treatment were collected.
Results The most common cause of SBS was necrotizing enterocolitis. Common clinical symptoms included watery stools, dehydration, and malnutrition. After treatment, the patient's weight, albumin, and prothrombin improved markedly. There are 72% of children with good or fair treatment results. The rate of sepsis was high (18%). There was one case with complications of catheter infection and one case of liver failure. Three children died during treatment, one died from septic shock and multiple organ failure, and two died from respiratory failure.
Conclusion This study showed promising treatment outcomes in pediatrics.
Cyber loss model risk translates to premium mispricing and risk sensitivity
Authors: Peters Gareth W. , Malavasi Matteo , Sofronov Georgy , Shevchenko Pavel V. , Trück Stefan , Jang Jiwook 
Published: March 2023

AbstractIn this paper we focus on model risk and risk sensitivity when addressing the insurability of cyber risk. The standard statistical approaches to assessment of insurability and potential mispricing are enhanced in several aspects involving consideration of model risk. Model risk can arise from model uncertainty and parameter uncertainty. We demonstrate how to quantify the effect of model risk in this analysis by incorporating various robust estimators for key model parameters that apply in both marginal and joint cyber risk loss process modelling. Through this analysis we are able to address the question that, to the best of our knowledge, no other study has investigated in the context of cyber risk: is model risk present in cyber risk data, and how does is it translate into premium mispricing? We believe our findings should complement existing studies seeking to explore the insurability of cyber losses.
The political influence of an interest group: A comparative study on the Muslim minority in the United States and Britain
Authors: Jan Einat 
Published: March 2023

AbstractThe article proposes to examine the existing political influence of the Muslim minority in the United States and Britain. The academic literature rarely refers to the component of political power as a tool that can explain the application of policy. Therefore, the analysis in the article will focus on several criteria comparatively between the two countries. The criteria include the influence of colonialism, the demography of the Muslim minority, the identity of the citizen as “Muslim”, integration policies, and the influence of the Muslim lobby. The article will show how these criteria prominently explain the political power of Muslim minorities in the intra-communal public sphere in Britain, in contrast to their relative weakness in the political sphere in the US. This is in accordance with the relative political power in each country. This article offers a new understanding of the political power of civic groups.
Cost stickiness, earnings forecast accuracy, and the informativeness of stock prices about future earnings: evidence from China
Authors: Li Jia , Sun Zhoutianyang 
Published: March 2023

AbstractThis paper uses the data from the Chinese capital market to study the relationship between cost stickiness, earnings forecast accuracy and stock price information content. The empirical results show that: (1) Cost stickiness significantly affects the earnings response coefficient of stock prices. Lower cost stickiness improves the ability of current returns to reflect future earnings, which is manifested in higher future earnings response coefficient (FERC). (2) Cost stickiness significantly reduces the future earnings response coefficient of non-state-owned enterprises, but does not reduce the future earnings response coefficient of state-owned enterprises. It can be seen that investors have different attitudes towards cost stickiness of listed companies with different property rights in the process of investment decision-making. (3) Cost stickiness significantly increases stock prices synchronicity and decreases the number of company-specific information reflected in stock prices. Further analysis shows that cost stickiness increases earnings forecast accuracy, which is the partial intermediary mechanism for cost stickiness to improve FERC and reduce stock price synchronicity. This paper not only enriches the relevant literature of cost stickiness and earnings response coefficient, but also shows that cost stickiness is an important factor affecting the information efficiency of capital market.
Using adult learning characteristics and the humanities to teach undergraduate healthcare students about social determinants of health
Authors: Brown Elizabeth A. , Kinder Hannah , Stang Garrett , Shumpert Wendy 
Published: March 2023

AbstractAuthors used an andragogy framework to help undergraduate allied health students better understand social determinants of health (SDOH) using a photo essay assignment. The study examined students’ perceptions of SDOH in various communities, description of health outcomes associated with their chosen SDOH, and lessons learned and suggestions to improve the assignment for future cohorts. Data were extracted from photo essays from 2019–2021 and entered in Microsoft Excel and Word for data analysis after course completion. Conventional qualitative content analysis was used to analyze student evaluation data from open-ended questions. Data were extracted from 53 student essays from 2019 to 2021. Most photo essays described communities in South Carolina (n = 42, 79.2%), urban areas (n = 37, 69.8%), or intermediary SDOH (75.5%). Several themes emerged concerning lessons learned (awareness and empathy are key to addressing SDOH), health equity (collaboration is necessary to provide resources, especially for underserved populations), and constructive feedback for the instructor (more time to discuss SDOH and assignment with peers and instructor). Faculty must work with students to think about more upstream factors like policy and cultural and societal values. Collecting evaluation data, specifically lessons learned and constructive feedback for faculty, can help faculty continuously improve course topics and assignments. Following a transparency framework can support student success and help faculty become effective leaders in the classroom while teaching subjects like SDOH and social justice.