bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERAPAN PIJAT OKSITOSIN UNTUK MENINGKATKAN PRODUKSI ASI PADA IBU POST PARTUM DI WILAYAH KERJA PUSKESMAS CENDRAWASIH MAKASSAR
Authors: Indriani  , Wirawati Amin  , Afriyani  
Published: August 2023

Setiap ibu menghasilkan Air Susu Ibu (ASI) yang merupakan pangan kompleks karena mengandung zat-zat gizi lengkap, yang merupakan nutrisi ideal untuk menunjang kesehatan, pertumbuhan dan perkembangan bayi secara optimal. Survey yang dilakukan oleh Helen Keller International pada tahun 2002 menyebutkan bahwa rata-rata bayi di Indonesia hanya mendapatkan ASI eksklusif selama 1,7 bulan. tujuan dari kegiatan ini adalah menerapkan pijat oksitosin untuk meningkatkan produksi ASI pada ibu post partum di Wilayah Kerja Puskesmas Cendrawasih Makassar. Kegiatan ini berbentuk intervensi fisik secara langsung pada ibu nifas/post partum, dimana pelaksanaannya dimulai dengan pemberian penyuluhan/health education tentang tujuan, manfaat dan cara melakukan pijat oksitosin. Penerapan pijat oksitosin diberikan pada ibu-ibu nifas dan dilakukan evaluasi pengaruh pijat oksitosin tersebut satu minggu kemudian. Hasil menunjukkan bahwa mayoritas responden melakukan penerapan ulang pijat oksitosin di rumah (86,40%), hal ini sejalan dengan jumlah ibu yang mengalami peningkatan produksi ASI (81,80%).
Latihan Model Samba Shoot Dan Fake Shoot Permainan Sepakbola Mahasiswa PJKR FIK UNMShooting merupakan salah satu kunci keberhasilan suatu tim untuk memperoleh peluang maupun menciptakan gol, lini depan suatu tim dianggap sukses ketika banyak melakukan sh
Authors: Zainuddin M.Said , Usman Arifuddin , Kamaruddin Ilham , Kamal Muhammad 
Published: August 2023

Shooting merupakan salah satu kunci keberhasilan suatu tim untuk memperoleh peluang maupun menciptakan gol, lini depan suatu tim dianggap sukses ketika banyak melakukan shooting ke area gawang lawan baik itu berbuah gol maupun dalam target. Pengetahuan dan pemahaman tentang model model shooting masih sangat kurang dilakukan oleh mahasswa PJKR FIK UNM. PKM ini dilaksanakan untuk Meningkatkan pengetahuan dan pemahaman tentang model model shooting yang baik dan benar dan meningkatkan kualitas dan intensitas penyerangan dalam satu tim. Metode yang digunakan adalah pemaparan materi manfaat model model shooting dilakukan dengan ceramah dan tanya jawab selanjutnya praktek model model shooting dilakukan dengan metode demonstrasi,ceramah dan tanya jawab. Hasil dari PKM ini yaitu peserta mampu memahami dan mempraktekkan dengan baik model samba shoot dan fake shoot sehingga dapat digunakan dan di aplikasikan baik itu dalam latihan maupun pertandingan,dengan begitu apa yang di harapkan tim dalam suatu pertandingan yaitu mencetak gol dapat terelisasi
SOSIALISASI BAHAYA SAMPAH PLASTIK TERHADAP EKOSISTEM LAUT BAGI REMAJA DESA UJONG PULAU RAYEUK, ACEH SELATAN
Authors: Nurul Najmi  , Endah Anisa Rahma  , Mai Suriani  , Rita Hartati  , Friyuanita Lubis  , Giovanni Oktavinanda  
Published: August 2023

Sampah plastik merupakan salah satu ancaman serius bagi ekosistem laut. Sampah plastik yang tersebar dilautan mengakibatkan penyumbatan, komplikasi, hingga kematian organisme laut. Tujuan dilaksanakan pengabdian kepada masyarakat ini adalah untuk memberikan gambaran kepada remaja desa tentang bahaya sampah plastik terhadap ekosistem laut, dan memberikan arahan serta pengetahuan kepada mereka tentang bahaya yang akan ditimbulkan. Pengabdian ini dilaksanakan pada tanggal 6 Februari Tahun 2022 di Pulau Dua, Desa Ujong Pulau Reyeuk, Kabupaten Aceh Selatan. Pelaksanaan sosialisasi dilaksanakan dalam beberapa tahap sebagai berikut: (1) Tahap Persiapan meliputi kebutuhan bahan logistik meliputi hand sanitizer, trash bag, spanduk sebagai informasi mengenai bahaya sampah plastik bagi ekosistem laut, (2) Tahap kegiatan meliputi penyisiran dan mengelilingi pulau dua untuk mengambil/memungut sampah; pemberikan atensi terhadap relawan yang ikut membantu dalam pengambilan sampah di Pulau Dua, (3) Tahap Pembuangan sampah ke dalam bak sampah yang disediakan oleh Pemerintah Daerah Kabupaten Aceh Selatan; serta edukasi melalui pemasangan spanduk mengenai menjaga lingkungan laut dengan tidak membuang sampah. Sampah plastik yang telah ditemukan di Pulau Dua Aceh Selatan menunjukkan bahwa minimnya kesadaran masyarakat mengenai kebersihan pesisir dan pantai. Oleh karena itu, pemeliharaan wilayah pesisir dan pantai di Pulau dua Aceh Selatan perlu ditingkatkan melalui himbauan dan saran edukasi agar masyarakat lebih peduli dalam menjaga lingkungan dan produktif dalam pengembangan ekosistem laut yang berkelanjutan
PENINGKATAN KUALITAS KEMASAN DAN PEMASARAN ONLINE TUSUK GIGI MOM’ LINA PADA UMKM DI DESA PRINGSEWU TIMUR
Authors: Wasilah  , Nisar  , M.I.Rizki  
Published: August 2023

UMKM tusuk gigi Mom’ Lina di desa Pringsewu timur mengalami penurunan dalam penjualan produk. Hal ini perlu diatasi untuk membantu keberlangsungan UMKM. Dalam upaya mengatasi permasalahan tersebut maka pengabdian ini bertujuan memberikan pendampingan dalam inovasi produk dan pemasaran. Membantu UMKM Tusuk Gigi Mom’ Lina di Desa Pringsewu Timur dalam pengayaan rasa, memperbaiki kemasan tusuk gigi yang dihasilkan.. Sedangkan pendampingan dalam pemasaran produk dilakukan dengan memanfaatkan media sosial berupa Whatsappp(WA) dan Istagram (IG). Perbaikan kemasan tusuk gigi, pengayaan rasa dan perluasan pemasaran diharapkan dapat membantu pelaku UMKM tusuk gigi di desa Pringsewu timur ini untuk meningkatkan volume penjualan.
مرونة سلسلة التجهيز وتأثيرها في بهجة الزبون -دراسة تحليلية
Authors: راضي نور عبدالرحمن , العزاوي أ.د. مها عارف بريسم , الجشعمي أ.د. كاظم احمد جواد 
Published: August 2023

يهدف البحث الى اختبار تأثير مرونة سلسلة التجهيز بأبعادها (مرونة المزيج، ومرونة المنتج الجديد، وخفة حركة سلسلة التجهيز ومرونة التوزيع) في بهجة الزبون، ولقد تجسدت مشكلة البحث بقلة اهتمام ادارة الشركة المبحوثة (الشركة العامة للصناعات الكهربائية والالكترونية) بتطبيق بعض ابعاد مرونة سلسلة التجهيز وبالشكل الذي يلبي حاجات ورغبات الزبائن المتجددة وبما يعزز تحقيق البهجة لهم، ولغرض تحقيق اهداف البحث والاجابة عن التساؤلات تم اعتماد الاستبانة كأداة لجمع البيانات التي وزعت على عينة قصدية قوامها (55) مبحوثا تمثلت بــــ (بمدير عام الشركة، ومعاونه، ومديري الاقسام، ومديري المصانع ووكلائهم)، وقد خضعت الاستبانة لاختبارات الصدق والثبات واعتماد عدد من الأساليب الإحصائية لمعرفة مستوى أهمية متغيرات البحث واختبار الفرضيات باستخدام البرنامج الاحصائي (SPSS V.28)، وقد اعتمد المنهج الوصفي - التحليلي.
وفي ضوء النتائج المتحققة التي كان اهمها وجود تأثير معنوي لمرونة سلسلة التجهيز في بهجة الزبون تمت صياغة عدد من الاستنتاجات كان اهمها ان ادارة الشركة المبحوثة تهتم بشكل متباين في تطبيق ابعاد مرونة سلسلة التجهيز لتحقيق بهجة الزبون، اذ انها تركز على بعدي خفة حركة سلسلة التجهيز ومرونة التوزيع ، مما يؤشر عمق روابط التعاون بين ادارة الشركة والمجهزين الذي يمنحها القدرة على التخلص من الانشطة التي لا تضيف قيمة ضمن سلسلة التجهيز وتقديم منتجات متنوعة تمتاز بالموثوقية والامان يتم تسليمها في مواعيدها المحددة، وبناء على ما تمت صياغته من استنتاجات تم وضع مجموعة من التوصيات كان اهمها زيادة الاهتمام باعتماد جميع ابعاد مرونة سلسلة التجهيز وبخاصة فيما يتعلق بمرونة المزيج ومرونة المنتج الجديد اذا ما ارادت ادارة الشركة تعزيز البهجة لزبائنها.
Metode PAIKEM untuk Meningkatkan Minat Baca
Authors: Leltakaeb Wilfrida , Lering Maria Ermilinda Dua , Lombo Lodovikus , Rimasi  
Published: August 2023

Tujuan penelitian ini untuk mengetahui minat baca dari peserta didik kelas VIII SMP Negeri Satap Oehoma, Nusa Tenggar Timur ketika menggunakan metode PAIKEM dalam pembelajaran Bahasa Indonesia. Penelitian ini menggunakan pendekatan kualitatif deskriptif karena dapat menggambarkan dan atau mendeskripsikan karakteristik dari fenomena. Metode PAIKEM dipilih untuk mengetahui minat baca karena metode ini menjadikan peserta didik aktif bertanya, mempertanyakan, dan mengemukakan gagasan. Kegiatan yang dilakukan adalah dengan materi pembuatan dan mewarnai slogan, membuat piramida cerita, membaca fabel, dan permainan menemukan istilah. Pelaksanaan metode ini ternyata membuat minat membaca peserta didik menjadi lebih baik sepuluh peserta bisa membaca, enam dari lima belas peserta didik belum lancar membaca dua puluh peserta didik memiliki kemauan untuk membaca dan belajar membaca, lima peserta didik butuh motivasi lebih.
The Effect of Perceived Risk on Consumer’s Online Purchase Intention at Zalora for Muslim Clothing Product
Authors: Permatasari Dea Nita , Muthohar Muchsin 
Published: August 2023

Aims: This study examines the effect of perceived risk on consumers' online purchase intention at e-commerce for a specific clothing product. Mainly, in this research, there are six perceived risk factors: Financial risk, product risk, security risk, time risk, social risk, and psychological risk.
Place and Duration of Study: This study was conducted in Indonesia, without any specific domicile in determining the respondents, from November 2022 to June 2023.
Design/Methodology: This study uses a quantitative approach with data collection methods in an online questionnaire and is determined using non-probability purposive sampling. Data was obtained by distributing online questionnaires to 250 respondents who know Zalora (following the predetermined criteria). This research was processed using IBM SPSS Statistic 26.
Results: This study's results show the negative effects of product risk and time risk on consumers' online purchase intention. On the other hand, it also shows that there is no effect from financial, security, social, or psychological risks on consumers' online purchase intention.
Enhancing Morpho-Physiological and Yield Potential of Rice using Nutrients and Plant Growth Regulators
Authors: Preethi V. , Ravichandran V. , Prasad V. Babu Rajendra , Iyanar K. , Karthikeyan R. 
Published: August 2023

Rice (Oryza sativa L.) is one of the major cereals and the staple food crops which is cultivated all over the world. In order to meet the growing demand of population, it is important to increase the productivity of crop. The productivity of crop is influenced by nutrients and growth hormones. With this background, a field experiment was conducted during the month of January-May 2023 at wetland farms, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India to evaluate the effect of different foliar nutrients and growth regulators on growth, physiology, biochemical and yield attributes in rice. The experimental layout was Factorial Randomized Block Design (FRBD) with two varieties (CO55 and ADT 57). The treatments consisted of foliar spray of T1- Control (water spray), T2- Nutrio-hormonal consortia 1, T3- Nutrio-hormonal consortia 2, T4- Rice booster 1 and T5- Rice booster 2 given at the booting stage and 15 days after the first spray. Among the treatments, T5- Rice booster 2 significantly improved leaf area (1813.99 cm2, 2059.78 cm2), leaf area index (4.53, 5.15), crop growth rate (32.07 g/m2/day, 37.89 g/m2/day), chlorophyll index (37.60, 41.73), photosynthetic rate (27.15 µmol CO2 m-2 s-1, 30.04 µmol CO2 m-2 s-1), Transpiration rate (11.83 mmol H2O m-1 s-1, 14.20 mmol H2O m-1 s-1 ), soluble protein content (16.23 mg/g, 17.30 mg/g), nitrate reductase activity (98.15 µg of NO2/g/h, 112.47 µg of NO2/g/h) in ADT- 57 variety at both sprays, respectively. Foliar application of rice booster 2 (T5) resulted in higher number of productive tillers (23), number of spikelets per panicle (165.5), spikelet fertility (95.48%), 1000 grain weight (17.35g), grain yield/ plant (31.40g), grain yield/hectare (6694.32 Kg/ha), harvest index (45.44%) in ADT 57 and resulted in 15% yield increment over the control. Thus the present study concluded that the foliar application of rice booster 2 (T5) significantly improved the growth, physiology, biochemical and yield attributes in rice variety ADT 57.
Dysphagia Outcomes Before and After Adenotonsillectomy in Children With Obstructive Sleep Apnea
Authors: Wang Chao , Hu Huiying , Sun Kai , Ma Yulong , Lu Yuanyuan , Liu Kai , Yu Zhenkun 
Published: August 2023

ImportanceObstructive sleep apnea (OSA) and tonsil hypertrophy may be associated with dysphagia. However, randomized clinical trials assessing dysphagia outcomes in children randomized to adenotonsillectomy (AT) vs watchful waiting with supportive care (WWSC) are lacking.ObjectiveTo assess dysphagia outcomes in children with OSA and tonsil hypertrophy managed with AT or WWSC.Design, Setting, and ParticipantsThis secondary analysis of a multicenter randomized clinical trial, the Childhood Adenotonsillectomy Trial (CHAT), was conducted at tertiary children’s hospitals from October 2007 to June 2012. Children aged 5.0 to 9.9 years with OSA were randomized to AT or WWSC and underwent polysomnography at baseline and 7 months. Caregivers completed the OSA-18 questionnaire, which includes an item on difficulty in swallowing at baseline and 7 months. The current secondary analysis was conducted from December 1, 2022, to January 10, 2023.InterventionsAT vs WWSC.Main Outcomes and MeasuresPrevalence of dysphagia, based on parental responses to the difficulty in swallowing item on the OSA-18 questionnaire, was redefined as a binary outcome at baseline and 7-month follow-up.ResultsIn total, 386 children were included (199 female [51.6%]; median [IQR] age, 6.0 [5.0-8.0] years). Of the total, 207 children were Black (53.6%). At baseline, the number of children with dysphagia was similar (4.0%; 95% CI, −4.9% to 12.9%) between the AT group (56 [29.8%]) and the WWSC group (51 [25.8%]). Following AT, a decrease was observed (21.3%; 95% CI, 13.5%-28.9%) in the prevalence of dysphagia among the children. In contrast, the prevalence of dysphagia did not change significantly (1.0%; 95% CI, −7.6% to 9.6%) in the WWSC group. Children in the AT group were more likely to experience a resolution of dysphagia than those in the WWSC group (adjusted odds ratio, 4.84; 95% CI, 1.91-12.25). Higher baseline AHI was associated with a lower resolution of dysphagia (AOR, 0.91; 95% CI, 0.83-0.98).Conclusions and RelevanceThis secondary analysis of the CHAT randomized clinical trial suggested that children with dysphagia and OSA undergoing AT may experience dysphagia improvement. A prospective randomized trial that uses a validated dysphagia survey is needed to verify the effectiveness of AT in treating dysphagia.Trial registrationClinicalTrials.gov Identifier: NCT00560859
Glycopolymers With On/Off Anchors: Confinement Effect on Regulating Dendritic Cells
Authors: Heng Xingyu , Shan Fangjian , Yang He , Hu Jun , Feng Ruyan , Tian Wende , Chen Gaojian , Chen Hong 
Published: August 2023

AbstractInsufficient activation or over‐activation of T cells due to the dendritic cells (DCs) state can cause negative effects on immunotherapy, making it crucial for DCs to maintain different states in different treatments. Polysaccharides are one of the most studied substances to promote DCs maturation. However, in many methods, optimizing the spatial dimension of the interaction between polysaccharides and cells is often overlooked. Therefore, in this study, a new strategy from the perspective of spatial dimension is proposed to regulate the efficacy of polysaccharides in promoting DCs maturation. An anchoring molecule (DMA) is introduced to existing glycopolymers for the confinement effect, and the effect can be turned off by oxidation of DMA. Among the prepared on‐confined (PMD2), off‐confined (PMD2‐O), and norm (PM2) glycopolymers, PMD2 and PMD2‐O show the best and worst results, respectively, in terms of the amount of binding to DCs and the effect on promoting DCs maturation. This sufficiently shows that the turn‐on and off of confinement effect can regulate the maturation of DCs by polysaccharides. Based on the all‐atom molecular dynamics (MD) simulation, the mechanism of difference in the confinement effect is explained. This simple method can also be used to regulate other molecule–cell interactions to guide cell behavior.
Perovskite Cathodes for Aqueous and Organic Iodine Batteries Operating Under One and Two Electrons Redox Modes
Authors: Li Xinliang , Wang Shixun , Zhang Dechao , Li Pei , Chen Ze , Chen Ao , Huang Zhaodong , Liang Guojin , Rogach Andrey L. , Zhi Chunyi 
Published: August 2023

AbstractAlthough conversion‐type iodine‐based batteries are considered promising for energy storage systems, stable electrode materials are scarce, especially for high‐performance multi‐electron reactions. The use of tin‐based iodine‐rich 2D Dion–Jacobson (DJ) ODASnI4 (ODA: 1,8‐octanediamine) perovskite materials as cathode materials for iodine‐based batteries is suggested. As a proof of concept, organic lithium‐perovskite and aqueous zinc‐perovskite batteries are fabricated and they can be operated based on the conventional one‐electron and advanced two‐electron transfer modes. The active elemental iodine in the perovskite cathode provides capacity through a reversible I−/I+ redox pair conversion at full depth, and the rapid electron injection/extraction leads to excellent reaction kinetics. Consequently, high discharge plateaus (1.71 V vs Zn2+/Zn; 3.41 V vs Li+/Li), large capacity (421 mAh g−1I), and a low decay rate (1.74 mV mAh−1 g−1I) are achieved for lithium and zinc ion batteries, respectively. This study demonstrates the promising potential of perovskite materials for high‐performance metal‐iodine batteries. Their reactions based on the two‐electron transfer mechanism shed light on similar battery systems aiming for decent operational stability and high energy density.
Thiamine metabolism dysfunction syndrome 5 (THMD5) mimicking acute disseminated encephalomyelitis
Authors: Thompson Zachary E. , Boyd Natalie K. , Khoshnood Mellad M. , Santoro Jonathan D. 
Published: August 2023

AbstractThiamine pyrophosphate (TPP), the substrate of Thiamine pyrophosphate kinase (TPK), is an important cofactor in carbohydrate metabolism, specifically as a cofactor of the Pyruvate dehydrogenase complex (PDH) complex. The nervous system is particularly dependent on TPP due to its reliance on glucose metabolism. In this case, a four‐year‐old girl had a previously unreported pathogenic variant of the gene encoding TPK (TPK1) which presented as Thiamine metabolism dysfunction syndrome 5 (THMD5; OMIM 614458). She had been diagnosed with acute disseminated encephalomyelitis and autism spectrum disorder (ASD), and initially presented with fever and agitation following vaccinations. After follow‐up with genetic testing, our patient was found to have compound heterozygous pathogenic variants of TPK1. After treatment with biotin and thiamine her clinical status improved, and her ASD features resolved. The presentation of our patient was consistent with previous reports and adds to the evidence that thiamine and biotin are effective treatments of TPK1 related metabolic deficiencies. The improvement of neurobehavioral symptoms in this case was marked, highlighting the importance of early identification and therapeutic intervention in this condition.
Protocol optimization of a targeted sequencing panel for genomic profiling of bronchoalveolar lavage fluid in lung cancer
Authors: Sather Cassandra L. , Yang Pamela , Zhang Chaomei , Fitzgibbon Matthew P. , Fournier Michelle , Toloza Eric , Tandon Amit , Schabath Matthew , Yoder Sean , Nair Viswam S. 
Published: August 2023

AbstractIntroductionWe investigated a commercially available sequencing panel to study the effect of sequencing depth, variant calling strategy, and targeted sequencing region on identifying tumor‐derived variants in cell‐free bronchoalveolar lavage (cfBAL) DNA compared with plasma cfDNA.MethodsSequencing was performed at low or high coverage using two filtering algorithms to identify tumor variants on two panels targeting 77 and 197 genes respectively.ResultsOne hundred and four sequencing files from 40 matched DNA samples of cfBAL, plasma, germline leukocytes, and archival tumor specimens in 10 patients with early‐stage lung cancer were analyzed. By low‐coverage sequencing, tumor‐derived cfBAL variants were detected in 5/10 patients (50%) compared with 2/10 (20%) for plasma. High‐coverage sequencing did not affect the number of tumor‐derived variants detected in either biospecimen type. Accounting for germline mutations eliminated false‐positive plasma calls regardless of coverage (0/10 patients with tumor‐derived variants identified) and increased the number of cfBAL calls (5/10 patients with tumor‐derived variants identified). These results were not affected by the number of targeted genes.
I still haven't found what I'm looking for: Early relational–developmental deficits and the search for repair through the erotic
Authors: Campion Nick 
Published: August 2023

AbstractBackgroundThis heuristic study explores the client's experience of seeking to repair early relational deficits through their sexual practices, preferences, desires and relationships.AimsThe aim of this study was to explore the hypothesis that a client's sexual practices, preferences, desires, relationships and needs can offer a direct opportunity to understand their early relational deficits.MethodologyThis study uses heuristic enquiry, seeking to capture the essence of participants' experiences. In‐person, semistructured interviews were conducted with four participants, and transcripts were analysed according to Moustakis' heuristic method.FindingsThe four research participants did seek repair in ways that aligned with the literature in terms of seeking a lost unity, searching for intimacy, to repair damage and resolve splits through the powerful contact of sex. The study demonstrates the irresistible power of the unconscious desire to address unmet needs and the destructive nature of the urgent search for intimacy—and suggests that although a repair through the erotic is sought, it is rarely found.
Expanding the Substrate Scope of N‐ and O‐Methyltransferases from Plants for Chemoselective Alkylation**
Authors: Jockmann Emely , Subrizi Fabiana , Mohr Michael K. F. , Carter Eve M. , Hebecker Pia M. , Popadić Désirée , Hailes Helen C. , Andexer Jennifer N. 
Published: August 2023

AbstractMethylation reactions are of significant interest when generating pharmaceutically active molecules and building blocks for other applications. Synthetic methylating reagents are often toxic and unselective due to their high reactivity. S‐Adenosyl‐l‐methionine (SAM)‐dependent methyltransferases (MTs) present a chemoselective and environmentally friendly alternative. The anthranilate N‐MT from Ruta graveolens (RgANMT) is involved in acridone alkaloid biosynthesis, methylating anthranilate. Although it is known to methylate substrates only at the N‐position, the closest relatives with respect to amino acid sequence similarities of over 60 % are O‐MTs catalysing the methylation reaction of caffeate and derivatives containing only hydroxyl groups (CaOMTs). In this study, we investigated the substrate range of RgANMT and a CaOMT from Prunus persica (PpCaOMT) using compounds with both, an amino‐ and hydroxyl group (aminophenols) as possible methyl group acceptors. For both enzymes, the reaction was highly chemoselective. Furthermore, generating cofactor derivatives in situ enabled the transfer of other alkyl chains onto the aminophenols, leading to an enlarged pool of products. Selected MT reactions were performed at a preparative biocatalytic scale in in vitro and in vivo experiments resulting in yields of up to 62 %.