bluuebunny/crossref_metadata_2025_split huggingface dataset:
A narrative review on the applications of intracavitary contrast-enhanced ultrasonography in pediatric lower genitourinary anomalies
Authors: Ren Jiayu , Ma Ting , Huang Shuyan , Chen Gongquan , Dietrich Christoph F. , Peng Yuexiang , Cui Xinwu 
Published: May 2023

PurposeWe mainly aimed to perform a narrative review of clinical applications of the three intracavitary contrast-enhanced ultrasonography (CEUS) including contrast-enhanced voiding urosonography (ceVUS), contrast-enhanced retrograde urethrosonography (ceRUG), and contrast-enhanced genitosonography (ceGS) in pediatric lower genitourinary anomalies.MethodA literature search in the PubMed and Web of Science databases was conducted up to 1 July 2022 on all studies published in English using the search terms “contrast-enhanced voiding urosonography”, “contrast-enhanced retrograde urethrosonography”, and “contrast-enhanced genitosonography”. Trials were limited to pediatric subjects (ages ≤18 years) with no time restrictions. The inclusion criteria were studies on ceVUS, ceRUG, and ceGS to evaluate pediatric lower genitourinary anomalies. Two independent authors summarized the included articles.ResultsFinally, a total of 48 original articles and 6 case reports or case series were included, of which 50 (93%) were only relevant to ceVUS, 3 (5%) articles involved ceGS, while only one (2%) article involved ceRUG, and 87% of the applications of ceVUS were focused on vesicoureteral reflux (VUR). We also searched 24 related reviews, of which 20 involved ceVUS in diagnosing VUR and 4 involved ceRUG and ceGS for other lower genitourinary anomalies.ConclusionIntracavitary CEUS including ceVUS, ceRUG, and ceGS in pediatrics has many advantages over other radiological examinations in diagnosing lower genitourinary anomalies. Although ceVUS is widely used in detecting VUR, ceRUG and ceGS have also become promising techniques for evaluating the urethral pathologies and urogenital sinus.
Herbal medicine, Banxia-xiexin tang, for functional dyspepsia: a systematic review and meta-analysis
Authors: Kim Keumji , Ko Seok-Jae , Cho Soo Ho , Kim Jinsung , Park Jae-Woo 
Published: May 2023

Background: The demand for complementary and alternative medicine for the management of functional dyspepsia (FD) is increasing due to the insufficient efficacy of conventional treatment options. In Asia, the Chinese herbal medicine formula Banxia-xiexin tang (BXT) has been used to treat FD.Methods: We searched 11 digital medical databases on 1 September 2021. Randomized controlled trials (RCTs) that investigated the efficacy of BXT or combination therapy (BXT plus Western medicines) for FD were selected. The outcome parameters were total clinical efficacy rate (TCE), motilin level, symptom checklist-90-revised (SCL-90-R), and visual analog scale (VAS) for dyspepsia and adverse events. Cochrane risk of bias tool 2.0 (RoB 2) was used for the quality assessment of included studies.Results: The meta-analysis comprised 57 RCTs with 5,525 participants. BXT was more efficacious, with a higher TCE than Western medicine. Combination therapy (BXT plus Western medicine) also resulted in a higher TCE than Western medicine. Combination therapy improved motilin levels and psychological symptoms to a greater extent than Western medicine, evidenced by a higher SCL-90-R score. However, no significant difference in VAS scores was observed between the BXT and placebo groups. BXT and combination therapy were associated with fewer adverse events than Western medicine or placebo.Conclusion: Our findings suggest that BXT and its combination therapy may be an effective and safe alternative treatment for FD. More RCTs with better methodologies are required to strengthen this evidence.Systematic Review Registration: [https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42019123285], identifier [CRD42019123285].
Elevated INR in a COVID-19 patient after concomitant administration of azvudine and anticoagulants
Authors: Zhang Xi , Jiao Fengwei , Li Guangrun , Yu Xiaojia , Pei Yuqing , Zhang Ying , Wang Zihui , Li Pengfei 
Published: May 2023

Background: Azvudine (FNC) is a promising treatment candidate for managing coronavirus disease 2019 (COVID-19). However, drug interactions with azvudine have been poorly studied, especially with no reported cases of azvudine with anticoagulants such as warfarin and rivaroxaban.Case summary: The patient was diagnosed with lower limb venous thrombosis and took warfarin regularly. The international normalized ratio (INR) was stable (2.0–3.0). However, the INR increased to 7.52 after administering azvudine. The patient had no other factors justifying this change. This increase in INR occurred again with the administration of azvudine in combination with rivaroxaban, and the INR increased to 18.91. After azvudine administration was stopped, the INR did not increase when rivaroxaban was used alone.Conclusion: Azvudine, warfarin, and rivaroxaban might have previously unidentified drug interactions that increased the INR. Therefore, the INR must be closely monitored when they are concomitantly administered in COVID-19 patients.
Neuropsychological considerations for long-duration deep spaceflight
Authors: Faerman Afik , Clark Jonathan B. , Sutton Jeffrey P. 
Published: May 2023

The deep space environment far beyond low-Earth orbit (LEO) introduces multiple and simultaneous risks for the functioning and health of the central nervous system (CNS), which may impair astronauts’ performance and wellbeing. As future deep space missions to Mars, moons, or asteroids will also exceed current LEO stay durations and are estimated to require up to 3 years, we review recent evidence with contemporary and historic spaceflight case studies addressing implications for long-duration missions. To highlight the need for specific further investigations, we provide neuropsychological considerations integrating cognitive and motor functions, neuroimaging, neurological biomarkers, behavior changes, and mood and affect to construct a multifactorial profile to explain performance variability, subjective experience, and potential risks. We discuss the importance of adopting a neuropsychological approach to long-duration deep spaceflight (LDDS) missions and draw specific recommendations for future research in space neuropsychology.
Factors associated with hospitalization times and length of stay in patients with bipolar disorder
Authors: Shi Xiaoning , Zhao Yingying , Yang Haichen , Xu Xiufeng , Fang Yiru , Yu Xin , Tan Qingrong , Li Huichun , Sun Guangqiang , Wu Hang , Wang Pengfei , Yang Jie , Zhu Xuequan , Wang Gang , Zhang Ling 
Published: May 2023

AimAppraise the clinical features and influencing factors of the hospitalization times and length of stay in bipolar disorder (BD) patients.MethodsThis is a multicenter, observational, cohort study of patients diagnosed of type I or type II bipolar disorder. Five hundred twenty outpatients in seven hospitals from six cities in China were recruited from February 2013 to June 2014 and followed up using a continuous sampling pattern. The research included a retrospective period of 12 months and the prospective period of 9 months. The demographic and clinical features of the patients were collected. The influencing factors that could affect the length of stay (number of days spent in the hospital in the prospective period) were analyzed by poisson's regression and the hospitalization times (times of hospitalization in the prospective and retrospective period) was analyzed by general linear model. The selected variables included gender, age, years of education, occupational status, residence status, family history of mental disease, comorbid substance abuse, comorbid anxiety disorder, times of suicide (total suicide times that occurred in the retrospective and prospective period), polarity of the first mood episode, and BD type(I/II).ResultsPoisson's regression analysis showed that suicide times [Incidence Rate Ratio (IRR) = 1.20, p &lt; 0.001], use of antipsychotic (IRR = 0.62, p = 0.011), and use of antidepressant (IRR = 0.56, p &lt; 0.001) were correlated to more hospitalization times. Linear regression analysis showed that BD type II (β = 0.28, p = 0.005) and unemployment (β = 0.16, p = 0.039) which might mean longer duration of depression and poor function were correlated to longer length of stay. However, patients who experienced more suicide times (β = −0.21, p = 0.007) tended to have a shorter length of stay.ConclusionOverall, better management of the depressive episode and functional rehabilitation may help to reduce the length of stay. BD patients with more hospitalization times were characterized by higher risk of suicide and complex polypharmacy. Patients at high risk of suicide tended to have inadequate therapy and poor compliance, which should be assessed and treated adequately during hospitalization.Clinical trial registrationwww.ClinicalTrials.gov, Identifier: NCT01770704.
Saying it out loud: explicit equity prompts for public health organization resilience
Authors: Haworth-Brockman Margaret , Betker Claire , Keynan Yoav 
Published: May 2023

IntroductionIn the early days of the COVID-19 pandemic there were numerous stories of health equity work being put “on hold” as public health staff were deployed to the many urgent tasks of responding to the emergency. Losing track of health equity work is not new and relates in part to the need to transfer tacit knowledge to explicit articulation of an organization’s commitment to health equity, by encoding the commitment and making it visible and sustainable in policy documents, protocols and processes.MethodsWe adopted a Theory of Change framework to develop training for public health personnel to articulate where and how health equity is or can be embedded in their emergency preparedness processes and documents.ResultsOver four sessions, participants reviewed how well their understanding of disadvantaged populations were represented in emergency preparedness, response and mitigation protocols. Using equity prompts, participants developed a heat map depicting where more work was needed to explicitly involve community partners in a sustained manner. Participants were challenged at times by questions of scope and authority, but it became clear that the explicit health equity prompts facilitated conversations that moved beyond the idea of health equity to something that could be codified and later measured. Over four sessions, participants reviewed how well their understanding of disadvantaged populations were represented in emergency preparedness, response and mitigation protocols. Using equity prompts, participants developed a heat map depicting where more work was needed to explicitly involve community partners in a sustained manner. Participants were challenged at times by questions of scope and authority, but it became clear that the explicit health equity prompts facilitated conversations that moved beyond the idea of health equity to something that could be codified and later measured.DiscussionUsing the indicators and prompts enabled the leadership and staff to articulate what they do and do not know about their community partners, including how to sustain their involvement, and where there was need for action. Saying out loud where there is – and is not – sustained commitment to achieving health equity can help public health organizations move from theory to true preparedness and resilience.
Mortality in Catalonia during the summer of 2022 and its relation with high temperatures and COVID-19 cases
Authors: Coma Ermengol , Pino David , Mora Núria , Fina Francesc , Perramon Aida , Prats Clara , Medina Manuel , Planella Antoni , Mompart Anna , Mendioroz Jacobo , Cabezas Carmen 
Published: May 2023

PurposeTo analyse the association between the mortality during the summer 2022 and either high temperatures or the COVID-19 wave with data from the Catalan Health Care System (7.8 million people).MethodsWe performed a retrospective study using publicly available data of meteorological variables, influenza-like illness (ILI) cases (including COVID-19) and deaths. The study comprises the summer months of the years 2021 and 2022. To compare the curves of mortality, ILI and temperature we calculated the z-score of each series. We assessed the observed lag between curves using the cross-correlation function. Finally, we calculated the correlation between the z-scores using the Pearson correlation coefficient (R2).ResultsDuring the study period, 33,967 deaths were reported in Catalonia (16,416 in the summer of 2021 and 17,551 in the summer of 2022). In 2022, the observed lag and the correlation between the z-scores of temperature and all-cause deaths was 3 days and R2 = 0.86, while between ILI and all-cause deaths was 22 days and R2 = 0.21. This high correlation between temperature and deaths increased up to 0.91 when we excluded those deaths reported as COVID-19 deaths, while the correlation between ILI and non-COVID-19 deaths decreased to −0.19. No correlation was observed between non-COVID deaths and temperature or ILI cases in 2021.ConclusionOur study suggests that the main cause of the increase in deaths during summer 2022 in Catalonia was the high temperatures and its duration. The contribution of the COVID-19 seems to be limited.
Soil health and synergy of ecological determinants of green cocoa productivity in different soil ecotypes in Ghana
Authors: Doe Eric Kofi , Attua Emmanuel Morgan , Obour Peter Bilson , Quaye Amos Kojo , Fosu-Mensah Benedicta Yayra 
Published: May 2023

IntroductionSoil health is critical for the efficient management of soil fertility and crop yield in “green” cocoa (GC) (Theobroma cacao L.) agroforestry systems. However, knowledge about agroecosystem factors that affect healthy soil productivity in “green” cocoa agroforestry systems is patchy in West Africa. Based on organic cocoa (OC) and conventional cocoa (CC) agroforestry systems in Ghana, this study examined the soil health and synergy of ecological factors that determine the yield of GC.MethodsUsing multi-stage random sampling, 11 CC and 11 OC farms were sampled from three soil types (ferralsols, lixisols, and leptosols) within selected agroecological zones. Socioeconomic and farm data, including bulked soil samples, were collected at 0–30 cm depth for analysis of soil chemical and physical properties.ResultsThe results showed intricate relationships between the ecological factors and the yield of GC (1.07 t ha−1), which comprised dry beans of OC (1.24 t ha−1) and CC (0.89 t ha−1). The green cocoa yield increased for fields owned by female farmers and for native farmers who inherited or outrightly owned farmlands. The cocoa yield was also positively related to physicochemical factors such as soil organic carbon (0.21%), pH (5.8), and carbon–nitrogen ratio (40.8%). The carbon–nitrogen ratio and pH together exerted the highest positive influence (0.62%) on the yield. Biological factors such as plant density (&gt;7 cocoa trees per 23.4 m2) and black pod rots reduced the cocoa yield.DiscussionThis study provides comprehensive empirical determinants of green cocoa productivity and offers a more reliable estimate of cocoa plant density. The findings suggest that Ghana's cocoa can be much greener if stakeholders promote healthy farm soil productivity and empower women who engage in soil organic carbon-conserving agroforestry.
Application of the oblique lateral interbody fusion technique in salvage surgery: technical note and case series
Authors: Han Jialuo , Han Shuo , Meng Shengwei , Zhao Xiaodan , Zhang Hao , Guo Jianwei , Xu Derong , Liu Houchen , Chen Mingrui , Ma Xuexiao , Wang Yan 
Published: May 2023

ObjectiveThe oblique lateral interbody fusion (OLIF) technique is a promising interbody fusion technique. This study summarizes the technical aspects of OLIF as a salvage surgery and the preliminary outcomes of a series of cases.Patients and methodsA retrospective review of patients with leg or back pain induced by pseudoarthrosis or adjacent segment disease after posterior lumbar interbody fusion/transforaminal lumbar interbody fusion was done. These patients underwent salvage OLIF surgeries in our institution from January 2021 to March 2022. Variables such as the demographic, clinical, surgical, and radiological characteristics of the enrolled patients were recorded and analyzed.ResultsEight patients (five females and three males; mean age 69.1 ± 5.7 years, range 63–80 years) were enrolled in this study. The mean operative time was 286.25 min (range: 230–440 min), and the estimated blood loss was 90 ml (range: 50–150 ml). Only one of the eight patients experienced a complication of lower limb motor weakness, which disappeared within 5 days after surgery. The latest data showed that the mean intervertebral space height increased from 8.36 mm preoperatively to 12.70 mm and the mean segmentary lordosis increased from 8.92° preoperatively to 15.05°. Bone fusion was achieved in all but one patient, who was followed up for only 3 months. The JOA scores Japanese Orthopaedic Association (JOA) Scores for low back pain of all patients significantly improved at the final follow-up.ConclusionOLIF provides a safe and effective salvage strategy for patients with failed posterior intervertebral fusion surgery. Patients effectively recovered intervertebral and foraminal height with no additional posterior direct decompression.
Pengaruh Kemampuan Dan Pengalaman Kerja Terhadap Kinerja Karyawan Pada PT Bunas Finance Indonesia (BFI Finance) Cabang Makassar
Authors: Mursidah Mursidah , Susianah Susianah , Albar Elyas 
Published: May 2023

<p align="justify">Tujuan penelitian ini untuk mengetahui dan menganalisis pengaruh kemampuan dan pengalaman kerja terhadap kinerja karyawan. Metode penelitian yang digunakan adalah penelitian deskriptif dengan pendekatan kuantitatif. Metode analisis data yang digunakan adalah regresi linear berganda. Populasi pada penelitian ini adalah karyawan PT Bunas <em>Finance </em>Indonesia (BFI <em>Finance)</em> Cabang Makassar, jumlah sampel dalam penelitian ini sebanyak 83 orang. Berdasarkan hasil pengujian hipotesis dalam penelitian ini menunjukkan bahwa secara simultan variabel Kemampuan dan pengalaman kerja tidak berpengaruh signifikan terhadap kinerja karyawan. Secara parsial variabel Kemampuan dan pengalaman kerja tidak berpengaruh secara signifikan terhadap kinerja karyawan. Nilai <em>R Square</em> yang diperoleh sebesar 0.017 menunjukkan bahwa variabel bebas Kemampuan dan Pengalama Kerja mampu menjelaskan variabel terikat yakni kinerja karyawan sebesar 1.7 %, sedangkan sisanya 98.3 % dijelaskan oleh faktor-faktor lain yang tidak diteliti dalam penelitian ini.</p><p><strong>Kata kunci</strong>: kemampuan, pengalaman kerja, kinerja karyawan</p>
Pengaruh Relative Advantage, Compatibility, Complexity, Observability Dan Trialability Terhadap Intention To Use Pada E-Wallet Dana
Authors: Jatmiko Muhammad Haryo , Imronudin Imronudin 
Published: May 2023

<p align="justify">The purpose of this study was to determine the effect of Relative advantage, Compatibility, Complexity, Observability, and Trialability on intention to use. This type of research is quantitative research. The population used in this study were students who used E-wallet Dana users, especially the Surakarta area, who had made online transactions using the E-wallet Dana application. The number of samples used was 162 respondents. The data collection method used in this study was the distribution of questionnaires. The research method used in this study uses SEM PLS. The results of this study relative advantage has a significant effect on the intention to use e-wallet, compatibility has a significant effect on the adoption of mobile payment, complexity does not significantly affect the intention to adopt e-wallet, observability has a significant effect on the intention to use e-wallet services, trialability has a significant effect on the intention to adopt e-wallet. a technology can be adopted and accepted by the community if its relative advantage, compatibility, trialability, and observability characteristics have a high value. This is because these characteristics have a favorable impact on technology adoption. In addition, a technology can also be adopted and accepted by the community if its complexity characteristic has a low value, because this characteristic has a negative effect on technology adoption.</p><p><strong>Keywords</strong>: Relative Advantage, Compatibility, Complexity, Observability, Trialability, Intention to Use</p>
Christian Social Ethics in A Multicultural Society
Authors: Franz Magnis-Suseno  
Published: May 2023

Christian social ethics mean the unfolding of the basic Christian witness into the multiple dimensions of human existence. This paper proceeds in five steps. First it recalls the basic witness Christians are called to give: that God is with us, that we may trust God and that we give witness to God's love thru our love. Second, it is stressed that by love is not meant an emotion, but an attitude and action: respect for a person, including her rights, care and responsibility for her well being, refusal to give room to hatred, jealousy and arrogance. Third this Christian love has to be unfolded thru the whole expanse of human existence, the cultural, political, social and economic dimensions. Humankind faces five serious challenges. The fourth section asks what specific challenges Indonesia faces and what is demanded of us. The paper ends, fifth, by suggesting four concrete areas where every follower of Jesus could make her or his witness become real.
Human And Divine Violence Problems in The Old Testament
Authors: Felisi Sorgwe  
Published: May 2023

The sixth commandment states, “You shall not kill” (Exodus 20:13). Not surprisingly, murder is a crime all over the world. But is violence always evil? Does it matter who the perpetrator is? Does the motivation matter? To say that violence is always evil is to forget that someone like Adolf Hitler could only have been stopped by using violence. The Hitlers and Osama Bin Ladens of this world are prepared to wipe out millions of people if they are not stopped, and the only way to stop them is by resorting to violence, for the only language such people understand is the language of violence. In general the perpetrator is always at fault, but the defender or the person who tries to mitigate the havoc being committed is justified. For that reason, while premeditated murder is a crime, it is not a crime to kill an intruder who comes into your home determined to kill as many people as possible and to rob you of as much of your belongings as possible.
Safety of Using Hydroxyethyl Starch Preparations in Infusion Therapy Programs
Authors: Кучко А.М. , Ефремова И.Н. , Федосеева И.И. 
Published: May 2023

Применение инфузионных растворов гидроксиэтилкрахмала (ГЭК) сопряжено с повышенным риском смертности и повреждения функции почек (в том числе потребностью в заместительной почечной терапии). Следует избегать использования растворов ГЭК по не одобренным Министерством здравоохранения Республики Беларусь показаниям в общей характеристике лекарственного препарата и инструкции по медицинскому применению лекарственного препарата. С целью минимизации рисков неблагоприятного воздействия при использовании растворов ГЭК Министерством здравоохранения утвержден ряд мер, направленных на обеспечение применения при превышении пользы над риском инфузионных растворов ГЭК у пациентов, находящихся в критическом состоянии, включающих информирование специалистов системы здравоохранения.
The use of infusion solutions of hydroxyethyl starches (HES) is associated with an increased risk of mortality and damage to kidney function (including the need for renal replacement therapy). The use of HES solutions for indications not approved by the Ministry of Health of the Republic of Belarus in the general characteristics and instructions for medical use should be avoided. As part of the functioning of the pharmacovigilance system, in order to minimize the risks of adverse effects when using HES solutions, the Ministry of Health approved a number of measures aimed at ensuring the use of HES in critically ill patients, when the benefit exceeds the risk, including informing healthcare professionals.