bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Kompetensi Kepribadian Dan Kompetensi Sosial Guru Terhadap Perilaku Sosial Siswa Di Sma Budi Darma Dumai
Authors: Lestari  
Published: February 2023

Prilaku sosial adalah sifat siswa untuk menaggapi orang lain dengan cara yang berbeda-beda, contohnya seperti melakukan kerjasama dalam mengerjakan tugas kelompok, mendahulukan kepentingan bersama daripada kepentingan sendiri. Prilaku sosial siswa dipengaruhi oleh bebrapa faktor diantaranya dari dalam diri dan faktor dari lingkungan luar. Penelitian ini bertujuan untuk mengetahui pengaruh kompetensi kepribadian dan kompetensi guru terhadap prilaku sosial siswa di SMA Budi Dharma Dumai. Penelitian ini menggunakan metode penelitian kuantatif. Subjek pada penelitian ini adalah siswa/siswi di SMA Budi Dharma Dumai.data dikumpulkan melalui penyebaran kuisioner. Kemudian data dianalisis menggunakan analisi regresi dengan bantuan SPSS21. Hasil penelitian menujukkan bahwa secara bersama-sama Kompetensi Kepribadian guru dan kompetensi sosial guru terhadap perilaku sosial sisawa di SMA Budi Darma Dumai berpengaruh sebesar 81,6% dan sebesar 19,4% dipengaruhi prilaku social siswa dipengaruhi oleh faktor lain.
Mänskliga rättigheter som innehåll i undervisningen.
Authors: Brantefors Lotta 
Published: February 2023

The study presented here shows how eleven-year-old children learn about their rights. Drawing theoretically on the Didaktik tradition, the purpose of the paper is to examine and identify the motives and content in teacher planned human rights education. The analyses show that the main purpose for teaching about rights is social and ethical: Children should learn to respect others, become good fellow humans and not discriminate. The educational content is dominated by four content themes: rights, democracy, discrimination, and protection. The choice of website and societal situation determines how the content is expressed and which rights are emphasised. In particular, violations of rights and children’s protection are stressed. Finally the Convention on the Rights of the Child is emphasised rather than the Declaration of Human Rights, and concepts like human rights, children’s rights and children’s human rights are used equally. The main conclusion is that rights and democratic values are mixed and rights are used without precision. Rights are cognitively weak but strong ethically and socially and mostly used as tools for discussions and social actions.
Association between coronary artery disease and incident cancer risk: a systematic review and meta-analysis of cohort studies
Authors: Chen Hsin-Hao , Lo Yi-Chi , Pan Wei-Sheng , Liu Shu-Jung , Yeh Tzu-Lin , Liu Lawrence Yu-Min 
Published: February 2023

Objective
Coronary artery disease (CAD) and cancer are the two leading causes of death worldwide. Evidence suggests the existence of shared mechanisms for these two diseases. We aimed to conduct a systematic review and meta-analysis to investigateassociation between CAD and incident cancer risk.

Methods
We searched Cochrane, PubMed, and Embase from inception until October 20, 2021, without language restrictions. Observational cohort studies were used to investigate the association between CAD and incident cancer risk. Using random-effects models, the odds ratio (OR) and 95% confidence interval (CI) were calculated. We utilized subgroup and sensitivity analyses to determine the potential sources of heterogeneity and explore the association between CAD and specific cancers. This study was conducted under a pre-established, registered protocol on PROSPERO (CRD42022302507).

Results
We initially examined 8,533 articles, and included 14 cohort studies in our review, 11 of which were eligible for meta-analysis. Patients with CAD had significantly higher odds of cancer risk than those without CAD (OR = 1.15, 95% CI = [1.08–1.22], I2 = 66%). Subgroup analysis revealed that the incident cancer risk was significantly higher in both sexes and patients with CAD with or without myocardial infarction. Sensitivity analysis revealed that the risk remained higher in patients with CAD even after >1 year of follow-up (OR = 1.23, 95% CI = [1.08–1.39], I2 = 76%). Regarding the specific outcome, the incident risk for colorectal and lung cancers was significantly higher (OR = 1.06, 95% CI = [1.03–1.10], I2 = 10%, and OR = 1.36, 95% CI = [1.15–1.60], I2 = 90%, respectively) and that for breast cancer was lower (OR = 0.86, 95% CI = [0.77–0.97], I2 = 57%) in patients with CAD than in those without CAD.

Conclusion
CAD may be associated with incident cancer risk, particularly for lung and colorectal cancers, in men and women as well as patients with or without myocardial infarction. Early detection of new-onset cancer and detailed cancer surveillance programs should be implemented in patients with CAD to reduce cancer-related morbidity and mortality.
Association of Conditional Cash Transfers With Maternal Mortality Using the 100 Million Brazilian Cohort
Authors: Alves Flávia Jôse O. , Ramos Dandara , Paixão Enny S. , Falcão Ila R. , de Cássia Ribeiro-Silva Rita , Fiaccone Rosemeire , Rasella Davide , Teixeira Camila , Machado Daiane Borges , Rocha Aline , de Almeida Marcia F. , Goes Emanuelle F. , Rodrigues Laura C. , Ichihara Maria Yury , Aquino Estela M. L. , Barreto Maurício L. 
Published: February 2023

ImportanceConditional cash transfers (CCTs) have been consistently associated with improvements to the determinants of maternal health, but there have been insufficient investigations regarding their effects on maternal mortality.ObjectiveTo evaluate the association between being a Bolsa Família program (BFP) beneficiary and maternal mortality and to examine how this association differs by duration of BFP receipt, maternal race, living in rural or urban areas, the Municipal Human Development Index (MHDI), and municipal primary health care coverage.Design, Setting, and ParticipantsThis cross-sectional analysis was nested within the 100 Million Brazilian Cohort. Girls and women aged 10 to 49 years (hereinafter referred to as women) who had at least 1 live birth were included, using data from Brazilian national health databases linked to the 100 Million Brazilian Cohort (January 1, 2004, to December 31, 2015). Propensity score kernel weighting was applied to control for sociodemographic and economic confounders in the association between BFP receipt and maternal mortality, overall and stratified by different subgroups (race, urban or rural area, and MHDI), and duration of BFP receipt. Data were analyzed from July 12, 2019, to December 31, 2022.Main Outcome(s) and MeasuresMaternal death.ResultsA total of 6 677 273 women aged 10 to 49 years were included in the analysis, 4056 of whom had died from pregnancy-related causes. The risk of maternal death was 18% lower in women who received BFP (weighted odds ratio [OR], 0.82 [95% CI, 0.71-0.93]). A longer duration receiving BFP was associated with an increased reduction in maternal mortality (OR for 1-4 years, 0.85 [95% CI, 0.75-0.97]; OR for 5-8 years, 0.70 [95% CI, 0.60-0.82]; OR for ≥9 years, 0.69 [95% CI, 0.53-0.88]). Receiving BFP was also associated with substantial increases in the number of prenatal appointments and interbirth intervals. The reduction was more pronounced in the most vulnerable groups.Conclusions and RelevanceThis cross-sectional analysis nested within the 100 Million Brazilian Cohort found an association between BFP receipt and maternal mortality. This association was of greater magnitude in women with longer exposure to BFP and in the most vulnerable groups. These findings reinforce evidence that programs such as BFP, which have already proven effective in poverty reduction, have great potential to improve maternal survival.
Recent Advances on High‐Speed and Holographic Two‐Photon Direct Laser Writing
Authors: Balena Antonio , Bianco Marco , Pisanello Ferruccio , De Vittorio Massimo 
Published: February 2023

AbstractTwo‐Photon Lithography, thanks to its very high sub‐diffraction resolution, has become the lithographic technique par excellence in applications requiring small feature sizes and complex 3D pattering. Despite this, the fabrication times required for extended structures remain much longer than those of other competing techniques (UV mask lithography, nanoimprinting, etc.). Its low throughput prevents its wide adoption in industrial applications. To increase it, over the years different solutions have been proposed, although their usage is difficult to generalize and may be limited depending on the specific application. A promising strategy to further increase the throughput of Two‐Photon Lithography, opening a concrete window for its adoption in industry, lies in its combination with holography approaches: in this way it is possible to generate dozens of foci from a single laser beam, thus parallelizing the fabrication of periodic structures, or to engineer the intensity distribution on the writing plane in a complex way, obtaining 3D microstructures with a single exposure. Here, the fundamental concepts behind high‐speed Two‐Photon Lithography and its combination with holography are discussed, and the literary production of recent years that exploits such techniques is reviewed, and contextualized according to the topic covered.
Molecular Evolution of Acceptor–Donor–Acceptor‐type Conjugated Oligomer Nanoparticles for Efficient Photothermal Antimicrobial Therapy
Authors: Yuan Huanxiang , Li Zelin , Zhao Qi , Jia Shaochuan , Wang Ting , Xu Li , Yuan Haitao , Li Shengliang 
Published: February 2023

AbstractInfectious diseases (such as wound infections) caused by pathogenic microorganisms can lead to serious consequences and even threaten life. The emergence of drug‐resistant bacteria has severely prevented the validity of traditional antibiotics. Therefore, developing novel antimicrobial strategies without drug‐resistant holds great promise for maximizing efficacy and minimizing the risk of drug‐resistance of resistant bacterial infections. Herein, near‐infrared (NIR)‐absorbing A–D–A type conjugated oligomers with a tunable backbone are designed and synthesized for regulating their photothermal conversion. After being assembled into nanoparticles, the conjugated oligomer CP‐F8P nanoparticles (NPs) containing a strong electron‐donating component show the strongest photothermal conversion efficiency of 81.6%. The low concentration of CP‐F8P NPs receive over 99% of antimicrobial efficiency against Ampr E. coli, S. aureus, and C. albicans upon NIR irradiation, and the phototherapy treatment of CP‐F8P NPs can effectively promote wound healing in diabetic mice with good biocompatibility. This work provides ideas for the design of efficient NIR‐activated antimicrobial reagents against drug‐resistant microbial infections.
Controllable Oxidation of ZrS2 to Prepare High‐κ, Single‐Crystal m‐ZrO2 for 2D Electronics
Authors: Jin Yuanyuan , Sun Jian , Zhang Ling , Yang Junqiang , Wu Yangwu , You Bingying , Liu Xiao , Leng Kai , Liu Song 
Published: February 2023

AbstractHigh‐κ materials that exhibit large permittivity and band gaps are needed as gate dielectrics to enhance capacitance and prevent leakage current in downsized technology nodes. Among these, monoclinic ZrO2 (m‐ZrO2) shows good potential because of its inertness and high‐κ with respect to SiO2, but a method to produce ultrathin single crystal is lacking. Here, the controllable preparation of ultrathin m‐ZrO2 single crystals via the in situ thermal oxidation of ZrS2 is achieved. As‐grown m‐ZrO2 presents an equivalent oxide thickness of ≈0.29 nm, a high dielectric constant of ≈19, and a breakdown voltage (EBD) of ≈7.22 MV cm−1. MoS2 field effect transistor (FET) by using m‐ZrO2 as a dielectric layer shows comparable mobility to that using SiO2 dielectric. The ultraclean interface of m‐ZrO2/MoS2 and high crystalline quality of m‐ZrO2 lead to negligible hysteresis in transfer curves. Single crystal m‐ZrO2 dielectric shows potential application in digital complementary metal oxidesemiconductor (CMOS) logic FET.
Extremely Strong and Tough Biodegradable Poly(urethane) Elastomers with Unprecedented Crack Tolerance via Hierarchical Hydrogen‐Bonding Interactions
Authors: Guo Rui , Zhang Qiang , Wu Youshen , Chen Hongbing , Liu Yanghe , Wang Jingjing , Duan Xianglong , Chen Quan , Ge Zhishen , Zhang Yanfeng 
Published: February 2023

AbstractThe elastomers with the combination of high strength and high toughness have always been intensively pursued due to their diverse applications. Biomedical applications frequently require elastomers with biodegradability and biocompatibility properties. It remains a great challenge to prepare the biodegradable elastomers with extremely robust mechanical properties for in vivo use. In this report, we present a polyurethane elastomer with unprecedented mechanical properties for the in vivo application as hernia patches, which was obtained by the solvent‐free reaction of polycaprolactone (PCL) and isophorone diisocyanate (IPDI) with N,N‐bis(2‐hydroxyethyl)oxamide (BHO) as the chain extender. Abundant and hierarchical hydrogen‐bonding interactions inside the elastomers hinder the crystallization of PCL segments and facilitate the formation of uniformly distributed hard phase microdomains, which miraculously realize the extremely high strength and toughness with the fracture strength of 92.2 MPa and true stress of 1.9 GPa, while maintaining the elongation‐at‐break of ≈1900% and ultrahigh toughness of 480.2 MJ m−3 with the unprecedented fracture energy of 322.2 kJ m−2. Hernia patches made from the elastomer via 3D printing technology exhibit outstanding mechanical properties, biocompatibility, and biodegradability. The robust and biodegradable elastomers demonstrate considerable potentials for in vivo applications.
Enhancing Multistep Reactions: Biomimetic Design of Substrate Channeling Using P22 Virus‐Like Particles
Authors: Wang Yang , Selivanovitch Ekaterina , Douglas Trevor 
Published: February 2023

AbstractMany biocatalytic processes inside cells employ substrate channeling to control the diffusion of intermediates for improved efficiency of enzymatic cascade reactions. This inspirational mechanism offers a strategy for increasing efficiency of multistep biocatalysis, especially where the intermediates are expensive cofactors that require continuous regeneration. However, it is challenging to achieve substrate channeling artificially in vitro due to fast diffusion of small molecules. By mimicking some naturally occurring metabolons, nanoreactors are developed using P22 virus‐like particles (VLPs), which enhance the efficiency of nicotinamide adenine dinucleotide (NAD)‐dependent multistep biocatalysis by substrate channeling. In this design, NAD‐dependent enzyme partners are coencapsulated inside the VLPs, while the cofactor is covalently tethered to the capsid interior through swing arms. The crowded environment inside the VLPs induces colocalization of the enzymes and the immobilized NAD, which shuttles between the enzymes for in situ regeneration without diffusing into the bulk solution. The modularity of the nanoreactors allows to tune their composition and consequently their overall activity, and also remodel them for different reactions by altering enzyme partners. Given the plasticity and versatility, P22 VLPs possess great potential for developing functional materials capable of multistep biotransformations with advantageous properties, including enhanced efficiency and economical usage of enzyme cofactors.
Bisphosphonate treatment at spondylo‐ocular syndrome due to a novel compound heterozygote variant in XYLT2 and review of the literature
Authors: Buyukyilmaz Gonul , Adiguzel Keziban Toksoy , Kılıc Esra 
Published: February 2023

AbstractSpondylo‐ocular syndrome is a rare autosomal recessive disorder characterized by generalized osteoporosis, hearing loss, visual impairment due to cataract, and platyspondyly. Previous studies have revealed that the syndrome is caused by pathogenic variants in the XYLT2 gene. A patient with spondylo‐ocular syndrome and two heterozygous pathogenic variant in the XYLT2 gene in compound state are described here. The patient presented with osteoporosis, platyspondyly, ocular findings, hearing loss, kyphosis, scoliosis, facial findings, intellectual disability, and undescended testicles. Previous reports of bisphosphonate treatment response were variable, whereas a long‐term follow‐up with bisphosphonate treatment in this case resulted in normalization of vertebral structures. Reporting such cases helps to determine the appropriate genotype–phenotype correlation in patients with XYLT2‐related pathogenesis.
Early prediction of Alzheimer's disease and related dementias using real‐world electronic health records
Authors: Li Qian , Yang Xi , Xu Jie , Guo Yi , He Xing , Hu Hui , Lyu Tianchen , Marra David , Miller Amber , Smith Glenn , DeKosky Steven , Boyce Richard D. , Schliep Karen , Shenkman Elizabeth , Maraganore Demetrius , Wu Yonghui , Bian Jiang 
Published: February 2023

AbstractIntroductionThis study aims to explore machine learning (ML) methods for early prediction of Alzheimer's disease (AD) and related dementias (ADRD) using the real‐world electronic health records (EHRs).MethodsA total of 23,835 ADRD and 1,038,643 control patients were identified from the OneFlorida+ Research Consortium. Two ML methods were used to develop the prediction models. Both knowledge‐driven and data‐driven approaches were explored. Four computable phenotyping algorithms were tested.ResultsThe gradient boosting tree (GBT) models trained with the data‐driven approach achieved the best area under the curve (AUC) scores of 0.939, 0.906, 0.884, and 0.854 for early prediction of ADRD 0, 1, 3, or 5 years before diagnosis, respectively. A number of important clinical and sociodemographic factors were identified.DiscussionWe tested various settings and showed the predictive ability of using ML approaches for early prediction of ADRD with EHRs. The models can help identify high‐risk individuals for early informed preventive or prognostic clinical decisions.
N‐Trifluoromethyl Succinimide as a New Reagent for Direct C−H Trifluoromethylation of Free Anilines
Authors: Liu Hao , He Xin , Chen Zhicheng , Zhang Jingchao , Fang Xinjie , Sun Zhizhong , Chu Wenyi 
Published: February 2023

AbstractN‐trifluoromethylsuccinimide (NTFS) as a new trifluoromethylation reagent was designed and prepared via Ag−CF3, and applied to the direct trifluoromethylation of free aniline, and a series of trifluoromethyl products were obtained with good yields. The practicability of the protocol was verified by a gram‐level experiment and the synthesis of the antiasthmatic drug Mabuterol. In addition, a possible radical mechanism was proposed and verified by related experiments. The protocol provided a new solution for C−H trifluoromethylation of free anilines.
Heterogenous morphogenesis of Caco‐2 cells reveals that flow induces three‐dimensional growth and maturation at high initial seeding cell densities
Authors: Dogan Asli Aybike , Dufva Martin 
Published: February 2023

AbstractHere, we introduce a customized hanging insert fitting a six‐well plate to culture Caco‐2 cells on hydrogel membranes under flow conditions. The cells are cultured in the apical channel‐like chamber, which provides about 1.3 dyn/cm2 shear, while the basolateral chamber is mixed when the device is rocked. The device was tested by investigating the functional impact of the initial seeding density in combination with flow applied at confluency. The low seeding density cultures grew in two dimensional (2D) irrespective of the flow. Flow and higher seeding density resulted in a mixture of three dimensional (3D) structures and 2D layers. Static culture and high cell seeding density resulted in 2D layers. The flow increased the height and ZO‐1 expression of cells in 2D layers, which correlated with an improved barrier function. Cultures with 3D structures had higher ZO‐1 expression than 2D cultures, but this did not correlate with an increased barrier function. 2D monolayers in static and dynamic cultures had similar morphology and heterogeneity in the expression of Mucin‐2 and Villin, while the 3D structures had generally higher expression of these markers. The result shows that the cell density and flow determine 3D growth and that the highest barrier function was obtained with low‐density cultures and flow.
A rare case of intraoral schwannoma in gingiva
Authors: Shaikh Fouzia , Jabade Bhagyashree , Sheikh Salika , Muglikar Sangeeta 
Published: February 2023

AbstractBackgroundSchwannomas are benign, slow‐growing encapsulated nodular lesions. As for the most benign encapsulated lesions, the treatment of choice is complete removal of the entire tissue with preservation of surrounding tissue.Methods and ResultsThe case presented is that of a 35‐year‐old female with the chief complaint of swelling on her gums in the lower left posterior region. Through intraoral and extraoral examinations the benign nature of the lesion was established. The excisional biopsy was carried out under local anesthesia, and the specimen was sent for histological examination, which gave a definite diagnosis of oral schwannoma. The patient was recalled at regular intervals so as to check for any recurrence of the lesion or occurrence of new lesions elsewhere in the body.ConclusionThe present case reemphasizes the importance of thorough clinical examination along with appropriate investigations, especially histopathological and immunohistochemical, for establishing a definitive diagnosis, which eventually plays an important role in the choice and execution of appropriate treatment at the earliest for the best prognosis and outcomes.Key pointsWhy is this case new information?

To the best of the author's knowledge, this the first case report of oral schwannoma diagnosed in gingiva in Indian population. This case presented a diagnostic dilemma due to its unusual location.
What are the keys to successful management of this case?

Schwannomas when completely excised have low rate of recurrence. Accurate diagnosis of the lesion along with complete physical examination and follow‐up at regular interval to rule out any recurrences are the keys to successful management of this case.
What are the primary limitations to success in this case?

Lack of data regarding residual tumor postoperative is a primary limitations to success of the case, as recurrence is associated with subtotal tumor removal.
Wohlfahrtiimonas chitiniclastica: A rare infection reported in an adult with liver cirrhosis
Authors: Kozyk Marko , Strubchevska Kateryna , Fisher Jordan 
Published: February 2023

AbstractWe present a case of a 60‐year‐old female with a history of liver cirrhosis, alcohol abuse, and chronic venous insufficiency who presented with maggot‐infested wounds on her legs, bilateral buttocks, and groin area. Two sets of blood cultures grew Wohlfahrtiimonas chitiniclastica. She underwent wound debridement and treatment with cefazolin.