bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring of heavy metal (zinc sulphate) toxicity by using pollen as Indicators - Pollen of Vigna unguiculata: Further Evidence of a Criticism of Banerji and Gangulee (1937), Dharurkar (1971-Ph.D. Thesis), Nair, Nambudiri and Thomas (1973), Berg (1973),
Authors: Salgare S. A. , Gawade Suwarna 
Published: February 2023

Zinc sulphate affected the germination of seed of Vigna unguiculata (L.) Walp. The treatment of 0.1 mg/ml of zinc sulphate showed the adverse effect on the phenology. It caused decrease in the fertility of pollen with an increase in the concentrations. This proves the gametocidic behaviour of the heavy metal. Though it affected the fertility of pollen, however, none of the concentration could bring down the fertility to zero percent. Potentiality of the germinability of pollen was noted in all the 4 series i.e. F, F-24, F-48, F-72 investigated. The heavy metal stimulated the germination of pollen of F, F-24 and F-48 series. All the concentrations of zinc sulphate inhibited the germination of pollen of F-72 series as well as the pollen tube growth of all the 4 series. The present investigation also shows that pollen germination and tube elongation are two different processes differing in their sensitivity to different concentrations of the heavy metal. It is also confirmed that the pollen development and activity are more sensitive indicators of adverse factors in the botanical environment and the use of an entire vascular plant as an indicator of pollution is a very crude method and rather a wrong choice.
A survey of plants used in homoeopathic pharmacy from Sirwel hills of Madhya Pradesh, India
Authors: Mahajan S. K. , Sapru Tripti , Dulkar C. L. , Mahajan Pooja 
Published: February 2023

The present paper deals with a preliminary survey of plants used in homoeopathic pharmacy from Sirwel hills situated in Khargone district of Madhya Pradesh. In all 35 angiospermic taxa belonging to 33 genera and 24 families reported, which are used in this therapy
Effect of textile effluent on chemical characteristics of Wunna river of Wardha District (M.S.)
Authors: Gandhewar S.S. , Vasudevan K. , Zade S. B. 
Published: February 2023

The paper describes the chemical characteristics of Wunna River at Hinganghat, Wardha district of Maharashtra State. Various chemical characteristics such as BOD, COD, total alkalinity, total hardness, total dissolved solids, chloride, sodium, nitrate, chromium and iron were studied at 3 different station of Wunna River viz. upstream region (S,), effluent mixed region (5,) and 700 m away from effluent mixed region (S,). Marginal variations in chemical characteristics were noticed at station 1 and 3. However, higher values were recorded at station 2 i.e. effluent mixed region. Data analysis indicates heavy pollution of eco system of the river at the site of release of textile industry waste water ie. S,
Study of the Activity of Antiviral Drugs Against the Causative Agent of Chikungunya Fever in Cell Culture
Authors: Loginova S. Ya. , Schukina V. N. , Savenko S. V. , Sakharov R. V. , Borisevich S. V. 
Published: February 2023

Сhikungunya virus (CHIKV) is a member of the Flavivirus genus, Flaviviridae family. It belongs to the zoonotic arbovirus infections transmitted by mosquitoes of the genus Aedes. In humans, this ﬂavivirus causes a disease known as Сhikungunya fever, etymologically related to yellow fever, dengue, West Nile, and Zika. There is no speciﬁc treatment for Сhikungunya fever, as there is no vaccine or preventive measures to date. A comparative analysis of the eﬀectiveness of chemotherapy drugs, interferon inducers and two classes of interferon α-, β-, and γ-showed that interferon drugs eﬀectively inhibit the reproduction of CHIKV in the Vero cell culture in a wide range of concentrations. Chemotherapy drugs Triazavirin® and Ingavirin® did not aﬀect the reproduction of CHIKV strain FN198/66 in Vero cell culture. Ribavirin® at a concentration of 100 µg/ml almost completely suppressed the reproduction of the CHIKV virus when the drug was introduced into the culture medium both before and after infection.
The First Experience of Combined Use of Cefepime/Sulbactam and Aztreonam in ICU Patients with Nosocomial Infections Caused by Carbapenem-Resistant Gram-Negative Microorganisms Producing Class B and D Carbapenemases
Authors: Suvorova M. P. , Sychev I. N. , Ignatenko O. V. , Burmistrova E. N. , Mirzakhamidova S. S. , Fedina L. V. , Vakolyuk R. M. , Yakovlev S. V. 
Published: February 2023

Background. The diﬃculties of antibacterial therapy of infections caused by carbapenemase-producing gram-negative bacteria are associated with limited options for adequate therapy since, in addition to resistance to carbapenems and other beta-lactams, these microorganisms are often characterized by associated resistance to other classes of antibiotics, including polymyxins. In vitro data support the idea of combined use of inhibitor-protected cephalosporins with aztreonam for the treatment of such infections. The aim of the study was to investigate the eﬀectiveness of cefepime/sulbactam (FEP/SB) in combination with aztreonam (ATM) in infections caused by class B and D carbapenemase producers.Methods. A prospective observational study evaluated the eﬀectiveness of the combination of FEP/SB + ATM in ICU patients with nosocomial infections complicated by sepsis or septic shock caused by carbapenem-resistant pathogens with documented production of class B or D carbapenemase. The ineﬀectiveness of previous treatment and the absence of other options for adequate therapy were used as inclusion criteria. Microbiological, clinical eﬃcacy, and 30-day mortality were indicators of therapy evaluation.Results. The study included 25 patients with nosocomial infection (76% of them was VAP), with sepsis (60%) or septic shock (40%) and an average SOFA score of 6 points caused by Klebsiella pneumoniae (23 patients) or Pseudomonas aeruginosa (2) producing carbapenemases OXA-48 (56%), NDM (20%), NDM + OXA-48 (16%), and class B carbapenemase in two strains of P. aeruginosa. The average daily dose of FEP/SB and ATM was 6.6 g, the duration of therapy was 9.9 days. As a result of the treatment, eradication was achieved in 68% of patients, clinical eﬃcacy was 72%, and the 30-day mortality rate was 28%.Conclusion. Our results show good clinical and bacteriological eﬃcacy of the combination of FEP/SB and ATM in infections caused by extremely resistant K. pneumoniae, non-susceptible to carbapenems and producing class B or D carbapenemase.
Prospects for Phagоtherapy of Bacterial Infections Associated with the Provision of Medical Care
Authors: Daudova A. D. , Abdrakhmanova R. O. , Yasenyavskaya A. L. , Demina Ju. Z. , Rubalsky M. O. , Rubalsky O. V. , Samotrueva M. A. , Bashkina O. A. 
Published: February 2023

Healthcare-associated infections (HAIs) are a global medical and socioeconomic problem. Nosocomial infections occupy one of the leading places among the causes of death in the Russian Federation. About 60–70% of all nosocomial infections are associated with the use of medical implants of various proﬁles. Pseudomonas aeruginosa, various types of streptococci, staphylococci, Escherichia coli, enterococci (Enterococcus faecalis), Klebsiella pneumoniae, Proteus mirabilis, and representatives of the genus Acinetobacter are highly likely to be found in bioﬁlms of medical supplies. A distinctive feature of microbes that cause HAIs is poly- or even pan-resistance of microbes to recommended antimicrobials. The search for methods and means to overcome is a priority task of modern medicine. Phage therapy seems to be one of the logical and promising ways to combat bacteria that are resistant to conventional therapy. The article outlines the advantages and disadvantages of phage therapy, provides an overview of the successful use of mono- and combined preparations of bacteriophages in the experiment and clinic, as well as modern directions for the use of bacteriophages not only for therapeutic, but also for prophylactic purposes, based on the latest achievements of genetic engineering and biotechnology.
Characteristic Scales of Complexity and Coherence within Interplanetary Coronal Mass Ejections: Insights from Spacecraft Swarms in Global Heliospheric Simulations
Authors: Scolini Camilla , Winslow Réka M. , Lugaz Noé , Poedts Stefaan 
Published: February 2023

Abstract
Many aspects of the 3D structure and evolution of interplanetary coronal mass ejections (ICMEs) remain unexplained. Here, we investigate two main topics: (1) the coherence scale of magnetic fields inside ICMEs, and (2) the dynamic nature of ICME magnetic complexity. We simulate ICMEs interacting with different solar winds using the linear force-free spheromak model incorporated into the EUHFORIA model. We place a swarm of ∼20,000 spacecraft in the 3D simulation domain and characterize ICME magnetic complexity and coherence at each spacecraft based on the simulated time series. Our simulations suggest that ICMEs retain a lower complexity and higher coherence along their magnetic axis, but that a characterization of their global complexity requires crossings along both the axial and perpendicular directions. For an ICME of initial half angular width of 45° that does not interact with other large-scale solar wind structures, global complexity can be characterized by as little as 7–12 spacecraft separated by 25°, but the minimum number of spacecraft rises to 50–65 (separated by 10°) if interactions occur. Without interactions, ICME coherence extends for 45°, 20°–30°, 15°–30°, and 0°–10° for B, B

ϕ
, B

θ
, and B

r
, respectively. Coherence is also lower in the ICME west flank compared to the east flank due to Parker spiral effects. Moreover, coherence is reduced by a factor of 3–6 by interactions with solar wind structures. Our findings help constrain some of the critical scales that control the evolution of ICMEs and aid in the planning of future dedicated multispacecraft missions.
The Nominal Ranges of Rocky Planet Masses, Radii, Surface Gravities, and Bulk Densities
Authors: Unterborn C. T. , Desch S. J. , Haldemann J. , Lorenzo A. , Schulze J. G. , Hinkel N. R. , Panero W. R. 
Published: February 2023

Abstract
The two primary observable quantities of an exoplanet—its mass and radius—alone are not sufficient to probe a rocky exoplanet’s interior composition and mineralogy. To overcome this, host-star abundances of the primary planet-building elements (Mg, Si, Fe) are typically used as a proxy for the planet’s bulk composition. The majority of small exoplanet hosts, however, do not have available abundance data. Here we present the open-source ExoPlex mass–radius–composition solver. Unlike previous open-source mass–radius solvers, ExoPlex calculates the core chemistry and equilibrium mantle mineralogy for a bulk composition, including effects of mantle FeO content, core light elements, and surface water/ice. We utilize ExoPlex to calculate the planetary radii, surface gravities, and bulk densities for 106 model planets up to 2 R
⊕ across these geochemistries, adopting the distribution of FGK stellar abundances to estimate of the range of bulk exoplanet compositions. We outline the 99.7% distribution of radii, surface gravities, and bulk densities that define planets as “nominally rocky.” Planets outside this range require compositions outside those expected from stellar abundance data, likely making them either Fe-enriched super-Mercuries, or volatile-enriched mini-Neptunes. We apply our classification scheme to a sample of 85 well-resolved exoplanets without available host-star abundances. We estimate only nine planets are within the “nominally rocky planet zone” at >70% confidence, while ∼20% and ∼30% of this sample can be reasonably classified as super-Mercuries or volatile-rich, respectively. Our results provide observers with a self-consistent way to classify broadly a planet as likely rocky, Mercury-like, or volatile-enriched, using mass and radius measurements alone.
Two new species of Sinopoda&nbsp;from China, with first description of the male of&nbsp;S. horizontalis&nbsp;Zhong, Cao &amp; Liu, 2017 (Araneae, Sparassidae)
Authors: Zhang Jianshuang , Xing Yuanqian , Yang Jinghui , Yu Hao , Zhong Yang 
Published: February 2023

Three species of spider genus Sinopoda Jäger, 1999 are reported from southern China. Two of them are described as new to science: S. guiyang Zhang, Yu & Zhong, sp. nov. and S. xishui Zhang, Yu & Zhong, sp. nov., both from Guizhou Province. The male of S. horizontalis Zhong, Cao & Liu, 2017 is described for the first time based on new material from type locatily, Wuyishan National Nature Reserve, Fujian Province, China. Detailed descriptions, diagnoses, photographs and a distribution map of the three species are provided.
Disponibilité des textes et performances en compréhension écrite à l’adolescence : quelle implication des fonctions exécutives ?
Authors: Potocki Anna , Chatelier Marion , Dyoniziak Yann , Pylouster Jean , Rouet Jean-François 
Published: February 2023

Les définitions récentes de la lecture insistent sur la nécessaire prise en compte du contexte dans lequel se réalise cette activité. Dans cette perspective, l’objectif de cette étude était d’étudier l’influence de deux situations de lecture (lire un texte en sachant que celui-ci restera – ou non – disponible au moment de répondre à des questions de compréhension) et des stratégies de lecture qui en découlent (intégrale vs . sélective) sur les performances en compréhension d’adolescents de 13-14 ans, et d’examiner le rôle différencié des fonctions exécutives dans ces deux situations. Les résultats montrent que la disponibilité des textes interagit avec les propriétés des textes (uniques vs . multiples) et des questions (bas vs . haut niveau). Par ailleurs, les compétences exécutives semblent préférentiellement impliquées dans les situations où le lecteur garde les textes à disposition au moment de répondre aux questions, suggérant qu’une telle situation relève d’une activité de lecture plus stratégique.
La Commission centrale pour la navigation du Rhin
Authors: Chambas Estelle 
Published: February 2023

La Commission centrale pour la navigation du Rhin est une institution emblématique, car elle a été la première organisation internationale. Son but était d’organiser le système de navigation sur le Rhin, en unifiant les droits de péage afin de faciliter les échanges et le commerce. Née au XIX e siècle, cette institution a su évoluer, d’abord péniblement, puis de plus en plus efficacement pour s’adapter aux nouveaux défis posés par la gestion d’un commun fluvial : le Rhin. Au fil du temps, cette Commission s’est consolidée malgré les guerres mondiales et a été investie d’un rôle particulièrement important au regard de l’enjeu stratégique de ce fleuve. Elle a préfiguré la gestion des communs fluviaux dont s’est aujourd’hui saisie l’Union européenne avec laquelle elle collabore désormais. Son histoire, relatée dans cet article, nous révèle ainsi que la Commission centrale pour la navigation du Rhin est une institution avant-gardiste trop méconnue.
Stickler and Wagner Syndrome in African Americans
Authors: Trinh Minh V. , Lee Jessica G. , Ferrone Philip J. 
Published: February 2023

Background:
Stickler (STL) and Wagner (WGN) syndromes are rare inherited vitreoretinopathies associated with retinal detachments (RD). There is a paucity of case reports describing these diseases in African American patients.

Methods:
An IRB-approved, retrospective chart review of African American patients with genetically proven ocular-only STL or WGN was performed, and 6 patients were identified.

Results:

Three patients had a
COL2A1
mutation, two had a
COL11A1
mutation, and one had a VCAN mutation. None had Pierre Robin facies. All were myopes with lattice degeneration and five had RD. Three underwent RD repair with vitrectomy (PPV), scleral buckle (SB), endolaser (EL), and silicone oil (SO). Two received laser retinopexy for localized RD and one received a prophylactic SB with 360° peripheral laser retinopexy.

Conclusion:
STL and WGN should be considered in myopic African American patients with lattice degeneration, giant retinal tears, abnormal vitreous, or spontaneous RD. Prophylactic laser treatment and aggressive surgical treatment of RD should be considered.

[
Ophthalmic Surg Lasers Imaging Retina
2023;54:97–101.]
Accuracy and Time Comparison Between Side-by-Side and Artificial Intelligence Overlayed Images
Authors: Cavichini Melina , Bartsch Dirk-Uwe G. , Warter Alexandra , Singh Sumit , An Cheolhong , Wang Yiqian , Zhang Junkang , Nguyen Truong , Freeman William R. 
Published: February 2023

Background and Objective:
The purpose of this study was to evaluate the accuracy and the time to find a lesion, taken in different platforms, color fundus photographs and infrared scanning laser ophthalmoscope images, using the traditional side-by-side (SBS) colocalization technique to an artificial intelligence (AI)-assisted technique.

Patients and Methods:
Fifty-three pathological lesions were studied in 11 eyes. Images were aligned using SBS and AI overlaid methods. The location of each color fundus lesion on the corresponding infrared scanning laser ophthalmoscope image was analyzed twice, one time for each method, on different days, for two specialists, in random order. The outcomes for each method were measured and recorded by an independent observer.

Results:

The colocalization AI method was superior to the conventional in accuracy and time (
P
< .001), with a mean time to colocalize 37% faster. The error rate using AI was 0% compared with 18% in SBS measurements.

Conclusions:
AI permitted a more accurate and faster colocalization of pathologic lesions than the conventional method.

[
Ophthalmic Surg Lasers Imaging Retina
2023;54:108–113.]
Evaluation of a Novel Local Drug Delivery System Containing Tetracycline Hydrochloride Microparticles as an Adjunct to Mechanotherapy in the Management of Chronic Periodontitis
Authors: Patil Nikita Dilip , Baburaj Mala Dixit , Narkhade Rajkiran , Athawale Rajani 
Published: February 2023

Background:
Tetracycline hydrochloride is a primarily used antimicrobial for periodontitis. Due to its limitations when used systemically, local application in the subgingival zone is encouraged. The local concentration of the drug can be maximized further by optimizing its delivery vehicle.

Aim and Objectives:
The aim was to compare and assess the efficacy of novel drug formulation containing tetracycline microparticles with commercially available tetracycline fibers as local drug delivery agents in patients with chronic periodontitis.

Materials and Methods:
A total of 10 patients in the age group of 23–53 years with chronic periodontitis were selected. Patients having isolated periodontal pockets with probing pocket depth (PPD) >5 mm were selected. They were randomized into Group A (scaling and root planning [SRP] + tetracycline microparticles) and Group B (SRP + tetracycline fibers). Clinical parameters such as plaque index, gingival index, probing pocket depth (PPD), and clinical attachment level (CAL) were recorded at 0 and 90 days. The data obtained were consolidated and subjected to statistical analysis.

Results:
Both the groups confirmed statistically significant improvement in all the clinical parameters. Results of the study showed enhanced CAL gain in Group A compared to Group B.

Conclusion:
The novel drug formulation is equally efficacious to the commercially available formulation, with decreased manufacturing cost and greater drug availability. Nevertheless, more clinical trials are necessary to study the long-term results.
Psychological Distress and Related Factors among Parents having Children with Cleft Lip and Palate Disorder
Authors: Senavirathne Aruni M. K. , Jayasekara Prasanna , Jayasekara Nethma Kalani 
Published: February 2023

Background:
Raising a child with a cleft lip and or palate disorder (CLPD) brings many challenges to the parents. Having children with CLPD can be a source of parental psychological distress (PPD). Stress experienced by parents may affect the development of a child. This study was designed to assess the prevalence and factors associated with PPD among parents having children with cleft lip and palate attending a major dental hospital in Sri Lanka.

Materials and Methods:
Cross-sectional study was conducted in cleft lip and palate clinics of Dental Hospital, Peradeniya, Sri Lanka. PPD was assessed using the General Health Questionnaire-30. Site of cleft and associated disabilities were recorded on data recording form using clinical records of the children. Chi-square and multivariate logistic regression analysis were used to analyze the data.

Results:
Out of 384 parents who accompanied their children to the clinic, 62.5% were mothers. The most common cleft site of the patients was cleft involving lip and palate (32.3%) and the least common site was isolated cleft of the soft palate (8.3%). The most common disability reported was speech problems (41.4%). The prevalence of PPD was 34%. Chi-square statistics showed that PPD was significantly associated with age of the child (P < 0.000), family income (P = 0.011), family structure (P < 0.000), previous knowledge on CLPD (P = 0.045), site of the cleft (P < 0.000), and disabilities associated with particular cleft (P < 0.000). Multivariate logistic regression analysis demonstrated that age of the child, family structure, cleft of the hard and soft palate, feeding difficulties, and speech problems were significant predictors for PPD.

Conclusion:
PPD is an important factor to consider in managing children having CLPD. This finding provides valuable information for the provision of multidisciplinary approach to manage PPD.
Evaluation between Flowable Composite and Conventional Pit-and-Fissure Sealant among School Children in Bengaluru City
Authors: Gupta Gaurav , Paul Arun , Naviwala Gulam Anwar , Prakash Deepa , Alex Prijitha 
Published: February 2023

Introduction:
Restorative dentistry has achieved remarkable developments in halting caries predominantly seen in pit and fissures. Flowable composite resin is predominantly used as pit-and-fissure sealants in recent years. The aim of our study was to compare the retentive properties of a flowable composite resin compared to a conventional sealant in 6–9 years school children over 18 months’ period.

Materials and Methods:
The study was a randomized controlled trail and conducted over a period of 18 months. Forty participants were randomly selected for this study from the private school. Flowable composite resin was used to seal the mandibular 1st molars on one side and conventional resin sealant was used on the other side.

Results:
The differences in the retention status between the sealants after 12 and 18 months were found statistically significant with P = 0.02 and P = 0.03, respectively. When the retention status was compared within the materials at different intervals, it was found to be statistically significant (P < 0.001).

Conclusion:
Conventional resin-based sealants had better retention rate at 12 and 18 months’ duration than the flowable composite resin.