bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accumulation of Heavy Metals by Bitter Lakes Macro- Algae in Egypt: Environmental Bioindicator
Authors: Abdel-Shafy Hussein I. , Ibrahim Amr M. 
Published: June 2023

Abstract
The potential of algae to accumulate heavy metals from marine environment was studied. The aim is to study the accumulation of Cd, Pb, Cu, Zn, Mn, Fe and Mg in the tissues of algae that grow in the little Biter Lake, Egypt. For this purpose, the level of metals in twelve different algal species were studied extensively. The investigated algae belong to: Green, Brown, and Red algae. The investigation includes the influence of seasonal variation on the rate of heavy metals accumulation by algae. Meanwhile, levels of metals in the Lake water were also assessed. The results indicated that there are differences between the metal concentration and the different algal species. Furthermore, differences were also found in the levels of different metals within the studied algae. The overall results showed that the highest accumulation rate was exhibited by Red algae followed by Green then Brown algal species. Correlation between the level of metals in the Lake Water, and the studied algal species was conducted to determine the concentration factors for each metal. It was concluded that the bioaccumulation of heavy metals by aquatic algae is an indication of the availability of those metals within the aquatic environment.
Disulfidptosis-related lncRNAs predict prognosis and immune response of colon adenocarcinoma
Authors: Li Sijun , long Qian , Nong Lanwei , Zheng Yanqing , Shao Honghua 
Published: June 2023

AbstractBackground Colon adenocarcinoma (COAD) is the most common type of colorectal cancer. Disulfidptosis is a novel method of disulfide-dependent cell death. Previous evidence suggested that targeting disulfidptosis may be a novel therapeutic strategy for cancer therapy. LncRNA also plays a key role in COAD. However, the mechanisms of disulfidptosis-related lncRNAs remain unknown, and the disulfidptosis-related lncRNAs-based signature for COAD remains less studied. Methods The transcriptional profile and clinical information of COAD were downloaded from The Cancer Genome Atlas (TCGA). Disulfidptosis-related gene (DRGs) expression profiles were analyzed. A correlation test, Cox regression analysis, and selection operator (LASSO) method were performed to determine a disulfidptosis -related lncRNA prognostic signature. Survival and predictive performance were analyzed according to Kaplan-Meier and receiver operating characteristic (ROC) curves. Nomograms and calibration curves were established. Gene set enrichment analysis (GSEA) was utilized to analyze the biological function. Tumor Immune Analysis was also employed to analyze the tumor immune microenvironment, immune cell infiltration, and immune function. Additionally, drug sensitivity analysis was employed to predict the sensitivity of antitumor drugs. Results We identified six DRGs as differentially expressed DRGs (DE-DRGs). Six disulfidptosis-related lncRNAs were identified and included in the novel prognostic signature. The Kaplan–Meier, and ROC curves demonstrated that the feature had acceptable predictive validity in the TCGA training, test, and complete sets. The disulfidptosis-related lncRNA model had higher diagnostic efficiency compared to other clinical features. Besides, significant differences in biological functions and pathway activities were observed between the low- and high-risk groups. The study constructed a disulfidptosis-related lncRNA signature for COAD. Additionally, six drugs were sensitive to COAD. Conclusion The six disulfidptosis-related risk profiles for lncRNA may help assess the prognosis and molecular profile of COAD patients and improve treatment options that can be further applied in the clinic.
Effects of acute caffeine ingestion on muscle strength, muscular endurance, rating of perceived exertion, and pain perception during strength exercise until the failure
Authors: Araújo Erivaldo M. , Gontijo Leandro P. , Oliveira Rafael X. , Sousa Caio V. , Júnior Hélio J. Coelho , Aguiar Samuel S. 
Published: June 2023

Abstract
Purpose
We aimed to examine the effects of acute caffeine ingestion on muscular strength, muscular endurance, rating of perceived exertion (RPE) and pain perception (PP) during strength exercise to failure.
Methods
Thirteen subjects (6 males, 7 females, 21.30 ± 0.71 years) participated in this randomized, double-blind, controlled experimental study. Participants ingested caffeine capsules (5 mg·kg− 1) or placebo one hour before a resistance exercise session at 90% 1RM and 50% 1RM, separated by at least 48 hours.
Results
The number of repetitions performed in the first and second series at 90% of 1RM of the bench press was significantly higher (p < 0.05) in the caffeine condition than the placebo. In the back squat, the first set in the caffeine condition was significantly greater (p < 0.05) in comparison to placebo. At 50% 1RM, the number of repetitions was higher in the caffeine session than the placebo in the bench press, back squat and leg press exercises (p < 0.05). RPE at 50% 1RM was lower (p < 0.05) in the caffeine session compared to the placebo session in the bench press, back squat, and supine row. The PP at 90% of 1RM was lower (p < 0.05) in the bench press in the first and second series about the placebo session.
Conclusion
In conclusion, caffeine intake can be used to obtain greater performance in strength training with lower PP and muscular endurance with lower RPE.
UPS design without inverter to power ISP servers
Authors: Shirzad Ehsan 
Published: June 2023

Abstract
Today, in order to provide continuous electricity to sensitive loads in centers such as banks, hospitals, telecommunication centers, military organizations and universities, uninterruptible power supply systems (UPS) should be used. The servers of the technology department of the mentioned centers can be considered as sensitive loads that must be continuously supplied with electricity. Many designs have been proposed for uninterruptible power supplies, all of which are based on rectifier and inverter circuits. In this article, a new method for UPS design is presented in order to provide continuous power to loads such as ISP servers, which, in addition to having proper performance, due to the removal of the inverter, the cost is also reduced compared to conventional UPS. The validity of the mentioned claim has been confirmed according to the results of the simulations in the Simulink MATLAB environment and the conducted experiments
Diffusion-driven frictional aging in silicon carbide
Authors: Nordhagen Even Marius , Sveinsson Henrik Andersen , Malthe-Sørenssen Anders 
Published: June 2023

Abstract
Friction is the force resisting relative motion of objects. The force depends on material properties, loading conditions and external factors such as temperature and humidity, but also contact aging has been identified as a primary factor. Several aging mechanisms have been proposed, including increased "contact quantity" due to plastic or elastic creep and enhanced "contact quality" due to formation of strong interfacial bonds. However, comparatively less attention has been given to other mechanisms that enhance the "contact quantity". In this study, we explore the influence of crystal faceting on the augmentation of "contact quantity" in cubic silicon carbide, driven by the minimization of surface free energy. Our observations reveal that the temporal evolution of the frictional aging effect follows a logarithmic pattern, akin to several other aging mechanisms. However, this particular mechanism is driven by internal capillary forces instead of the normal force typically associated with friction. Due to this fundamental distinction, existing frictional aging models fail to comprehensively explain the observed behavior. In light of these findings, we derive a model for the evolution of contact area caused by diffusion-driven frictional aging, drawing upon principles from statistical mechanics. Upon application of a normal force, the friction force is increased due to plastic creep. This investigation presents an alternative explanation for the logarithmic aging behavior observed and offers the potential to contribute to the development of more accurate friction models.
Simultaneous improvement of fructofilicity and ethanol tolerance of Saccharomyces cerevisiae strains through a single Adaptive Laboratory Evolution strategy
Authors: Mavrommati Maria , Economou Christina N. , Kallithraka Stamatina , Papanikolaou Seraphim , Aggelis George 
Published: June 2023

Abstract
Saccharomyces cerevisiae is the main yeast used in the winemaking industry. Its innate glucofilicity provokes a discrepancy in glucose and fructose consumption during alcoholic fermentation of grape must, which, combined with the inhibitory effect of ethanol accumulated in the fermentation broth, might lead to stuck or sluggish fermentations. In the present study, we realized an Adaptive Laboratory Evolution strategy, where an alcoholic fermentation of a 20 g L− 1 fructose broth was followed by cell selection in a high ethanol concentration environment, employed in two different S. cerevisiae strains, named CFB and BLR. The evolved populations originated from each strain after 100 generations of evolution exhibited diverse fermentative abilities. One evolved population, originated from CFB strain, fermented a synthetic broth of 100 g L− 1 glucose and 100 g L− 1 fructose to dryness in 170 h, whereas the parental strain did not complete the fermentation even after 1000 h of incubation. The parameters of growth of the parental and evolved populations of the present study, as well as of the ethanol tolerant populations acquired in a previous study, when grown in a synthetic broth of 100 g L− 1 glucose and 100 g L− 1 fructose, were calculated through a kinetic model and were compared to each other in order to identify the effect of evolution on the biochemical behavior of the strains. Finally, in a fermentation at synthetic broth with 200 g L− 1 fructose only the evolved population derived from CFB strain showed improved fermentative behavior than its parental strain.
A 4-hydroxybenzoate 3-hydroxylase mutant enables 4-amino-3-hydroxybenzoic acid production from glucose in Corynebacterium glutamicum
Authors: Nonaka Kyoshiro , Osamura Tatsuya , Takahashi Fumikazu 
Published: June 2023

Abstract
Background
Microbial production of aromatic chemicals is attractive as a means of obtaining high-performance materials from biomass resources. A non-proteinogenic amino acid 4-amino-3-hydroxybenzoic acid (4,3-AHBA) is expected to be a precursor of highly functional polybenzoxazole polymers; however, its microbial production methods have not been reported. In this study, we attempted to produce 4,3-AHBA from glucose by introducing 3-hydroxylation of 4-aminobenzoic acid (4-ABA) in the metabolic pathway of the industrially relevant bacterium Corynebacterium glutamicum.
Results
Six different 4-hydroxybenzoate 3-hydroxylases (PHBHs) were heterologously expressed in C. glutamicum strains and screened by detecting the concentration of 4,3-AHBA produced following cultivation using glucose as the carbon source. The highest 4,3-AHBA concentration was detected in the strain expressing PHBH from Caulobacter vibrioides (CvPHBH). The combination of site-directed mutagenesis in the active site and random mutagenesis via laccase-mediated colorimetric assay allowed us to obtain CvPHBH mutants that enhanced 4,3-AHBA productivity under deep-well plate culture conditions. The recombinant C. glutamicum strain expressing CvPHBHM106A/T294S and having an enhanced 4-ABA biosynthetic pathway produced 13.5 g/L (88 mM) of 4,3-AHBA and 0.059 g/L (0.43 mM) of the precursor 4-ABA in the fed-batch culture.
Conclusions
Identifying PHBH mutants that efficiently catalyze the 3-hydroxylation of 4-ABA in C. glutamicum allowed us to construct an artificial biosynthetic pathway capable of producing 4,3-AHBA on a gram-scale using glucose as the carbon source. These findings will contribute to an improved understanding of enzyme-catalyzed regioselective hydroxylation of aromatic chemicals and to the diversification of biomass-derived precursors for high-performance materials.
Spatial Distribution and Determinants of Unskilled Birth Attendance in Ethiopia: Spatial and Multilevel Analysis
Authors: Sisay Gizaw , Mulat Tsion 
Published: June 2023

Abstract
Introduction: Deliveries performed by unskilled birth attendants contribute to maternal and newborn deaths in low-and middle-income countries such as Ethiopia, where only 28% of women give birth by skilled health personnel. Hence, this study was aimed to examine spatial variation and associated factors of unskilled birth attendance in Ethiopia.
Methods: This study used a total weighted sample of 7579 women who had a live birth in the five years preceding the survey obtained from 2016 EDHS data were included in the analysis. ArcGIS 10.7 software was used to detect areas with a high prevalence of unskilled birth attendance in Ethiopia. Besides, a multilevel binary logistic regression analysis was done to identify the determinant factors of UBA delivery.
Results: Based on the 2016 EDHS, the overall national prevalence of unskilled birth attendants was more than three-fourth (66.93 %) with 95% CI (66.39, 69.12 66.93 %). In the multivariable multilevel binary logistic regression model; women age group, women attained primary and above educational level, women in the middle and richest household wealth status, mass media exposure, ANC visits, region, place of residence and health insurance coverage were significantly associated with unskilled birth attendance. The spatial distribution analysis of unskilled birth attendant was significantly varied across the country with the significant hotspot areas in the eastern Somali, western Gambela, central and eastern Amhara, southwestern Oromia, eastern border of SNNP region were detected.
Conclusion: The national prevalence of unskilled birth attendance delivery in Ethiopia was still more than three-fourth. The geospatial distribution of UBAs was varied across the country. Maternal age group, education level, rural residence, ANC visits, mass media exposure, wealth status, health insurance coverage and barriers in accessing healthcareservice were determinants of unskilled birth attendants. Hence, improving maternal educational level, special interventional design in hotspot areas, and motivate the women to take antenatal care is vital to decrease the prevalence of unskilled attendance delivery.
Ontology Driven Machine Learning Models for the Classification of Social Media Data: A Systematic Literature Review
Authors: KERO ADMAS ABTEW , Demissie Dait , Kekeba Kula 
Published: June 2023

Abstract
This systematic literature review aims to explore the challenges and limitations of applying ontology driven machine learning models to the classification of social media data. Social media platforms generate a vast amount of data that requires automated and reliable classification to facilitate analysis and decision-making. Ontology driven machine learning models offer a promising approach to address this need by harnessing the power of both ontologies and machine learning algorithms to improve accuracy and efficiency. However, the application of such models to social media data classification poses unique challenges due to the complex and dynamic nature of social media data. To address this research gap, a systematic literature search was conducted, and 20 studies were included in the review. The findings of this review suggest that ontology driven machine learning models offer a promising approach to address the challenges of social media data classification. However, the existing literature highlights several challenges that need to be addressed, such as ontology development, feature selection, and model validation. Overall, the review provides insights into the current state of research on ontology driven machine learning models for social media data classification, identifies research gaps, and suggests directions for future investigation.
The Diophantine equation $\displaystyle a \left(\frac{b^k - 1}{b - 1}\right) = \mathcal{U}_n - \mathcal{U}_m$
Authors: Tiebekabe P. , Diouf I. , Tall A. , Kakanou K. R. 
Published: June 2023

Abstract
Here, we find all positive integer solutions of the Diophantine equation in the title, where $(\mathcal{U}_n)_{n\geqslant 0}$ is the generalized Lucas sequence $\mathcal{U}_0=0, \ \mathcal{U}_1=1$ and $\mathcal{U}_{n+1}=r \mathcal{U}_n +s \mathcal{U}_{n-1}$ with $r$ and $s$ integers such that $\Delta = r^2 +4 s >0$.
Dynamic head loss in pilot- and full-scale wastewater sand filtration with phosphorus removal, denitrification, and associated bumping
Authors: Jonsson Lena Margareta , Björlenius Berndt 
Published: June 2023

Abstract

Limitations of the operation of down-flow sand filters were investigated without and with dosages of methanol, ethanol, or acetate for denitrification and dosages of ferrous sulphate to remove phosphorous. The dynamic head loss was developed due to clogging by suspended solids (SS) that originated from the secondary sedimentation tanks including sludge overflow and from SS in primary settled wastewater that bypassed the biological step. The dynamic head loss was also developed from clogging by gas bubbles formed during denitrification, not by the SS produced from cell growth. The dynamic head loss in sand filters after 24 h operation without and with denitrification increased by 0.9–1.3 and 2.3–2.4 mH2O, respectively. The total time of operation was prolonged by 50% after one water bumping, by 75% after two bumpings, and by 85% after six or seven bumpings. Operational time for filter cycles was prolonged by 4–5 h by one bumping in the full-scale and pilot-scale filters. The time of operation depended on hydraulic loading. With a carbon source dosage, one filter cycle lasted 20–40 h at 10 m/h and 60 h at 5 m/h in pilot-scale filters, and 15–27 h at 3.3 m/h in full-scale filters.
Respon Tanaman Cabai (Capsicum frutescens L.) Pada Pemberian Pupuk Mono Kalium Phosphate Dan Pupuk Organik Terhadap Pertumbuhan Dan Produksi
Authors: Made Naratama Nugraha  , Luh Kartini  , Anak Agung Ngurah Mayun Wirajaya  
Published: June 2023

Penelitan ini bertujuan untuk mengetahui pengaruh pemberian pupuk MKP, pupuk organik padat kelinci serta interaksi pupuk MKP dengan pupuk organik padat kelinci terhadap pertumbuhan dan hasil tanaman cabai rawit. Penelitian ini dilakukan di Subak Rapuan, Desa Mas, Kecamatan Ubud, Kabupaten Gianyar dengan ketinggian tempat 400 mdpl. Percobaan berlangsung selama 4 bulan yaitu pada bulan Mei sampai dengan bulan Juli 2022. Percobaan ini menggunakan Rancangan Acak Kelompok (RAK) dengan 2 faktor yang disusun secara faktorial. Faktor pertama adalah menggunakan pupuk MKP dengan 4 taraf, yaitu M0: 0 g l-1 air, M1: 2 g l-1 air, M2: 4 g l-1 air, M3: 6 g l-1 air dan faktor kedua adalah menggunakan pupuk organik padat kelinci yang terdiri dari 3 taraf, yaitu P1: 10 ton ha-1, P2: 20 ton ha-1 dan P3: 30 ton ha-1 . Pengamatan tinggi tanaman, jumlah daun, jumlah bunga, dan jumlah buah akan dimulai 3 minggu setelah tanam, sedangkan berat segar dan berat kering buah dan brangkasan akan diukur saat akhir panen. Hasil analisis statistik menunjukkan pemberian pupuk MKP pada tanaman cabai rawit berpengaruh sangat nyata pada variabel jumlah daun maksimum, jumlah, jumlah bunga, jumlah buah total dan berat segar buah serta berpengaruh tidak nyata pada tinggi tanaman maksimum, berat kering oven buah, berat segar brangkasan dan berat kering oven brangkasan. Perlakuan pemberian pupuk organik kelinci menunjukkan pengaruh nyata hingga sangat nyata terhadap seluruh variabel yang diamati kecuali pada variabel jumlah daun maksimum dan berat kering oven buah yang menunjukkan pengaruh tidak nyata. Interaksi antara perlakuan pengaruh pupuk MKP dengan pupuk organik kelinci berpengaruh sangat nyata pada tinggi tanaman maksimum, berpengaruh nyata pada jumlah daun maksimum, jumlah bunga, jumlah buah total, berat segar buah, berat kering oven buah dan berat kering oven brangkasan.
PENAMAAN PESANTREN DI LAMONGAN: KAJIAN SEMANTIK
Authors: Zahidi Mohammad Khikam , Alfi Khoiru An Nisa  
Published: June 2023

Tujuan penelitian ini adalah mengidentifikasi bentuk dan makna penamaan pesantren di lamongan. Pendekatan deskriptif merupakan pendekatan yang digunakan dalam penelitian ini. Pendekatan deskriptif digunakan untuk membuat deskripsi atau gambaran, lukisan secara sistematis, faktual dan akurat mengenai data, sifat-sifat serta hubungan fenomena-fenomena yang diteliti. Penelitian ini menggunakan metode kualitatif. Metode ini digunakan ketika menghimpun dan menganalisa data tentang nama pesantren. Metode pengumpulan data yang digunakan adalah metode observasi, wawancara, dan rekam. Teknik analisis data dilakukan dengan mengumpulkan nama-nama pesantren di lamongan menganalisis bentuk dan makna penamaannya. berdasarkan pengamatan dan analisis data mengenai lingkungan biotik dan abbiotik ditemukan (1) makna nama pengharapan futuratif, (2) makna nama pengharapan situasional, (3) makna nama kenangan, (4) cara penamaan lingkungan biotik, (5) cara penamaan lingkungan abiotik.
Tujuan penelitian ini adalah mengidentifikasi bentuk dan makna penamaan pesantren di lamongan. Pendekatan deskriptif merupakan pendekatan yang digunakan dalam penelitian ini. Pendekatan deskriptif digunakan untuk membuat deskripsi atau gambaran, lukisan secara sistematis, faktual dan akurat mengenai data, sifat-sifat serta hubungan fenomena-fenomena yang diteliti. Penelitian ini menggunakan metode kualitatif. Metode ini digunakan ketika menghimpun dan menganalisa data tentang nama pesantren. Metode pengumpulan data yang digunakan adalah metode observasi, wawancara, dan rekam. Teknik analisis data dilakukan dengan mengumpulkan nama-nama pesantren di lamongan menganalisis bentuk dan makna penamaannya. berdasarkan pengamatan dan analisis data mengenai lingkungan biotik dan abbiotik ditemukan (1) makna nama pengharapan futuratif, (2) makna nama pengharapan situasional, (3) makna nama kenangan, (4) cara penamaan lingkungan biotik, (5) cara penamaan lingkungan abiotik.
DAMPAK SIGNIFIKAN PENAMBAHAN FONEM ‘-NG’ PADA LIRIK LAGU CELENG GULING; WIDI-WIDIANA TERHADAP MAKNA
Authors: Setiadi I Gede Dwi 
Published: June 2023

Penelitian ini merupakan bentuk penelitian semantik tetapi dengan cara memodifikasi unsur fonologi di dalamnya. Sebagaimana diketahui bahwa perubahan kecil dan mendasar dalam struktur sintaksis akan memengaruhi maknanya. Penelitian ini menggunakan metode kualitatif dan metode eksperimen. Metode kualitatif bermaksud untuk memahami fenomena tentang apa yang dialami oleh subjek penelitian seperti persepsi, motivasi, tindakan, dan lain-lain secara holistik, dengan cara deskripsi dalam bentuk kata-kata bahasa. Dalam hal ini metode kualitatif diterapkan dalam melakukan analisis terhadap data penelitian yaitu lagu Celeng Guling oleh Widi-Widiana. Kemudian metode eksperimen adalah metode untuk mengetahui akibat dari perlakuan yang diberikan terhadap suatu hal yang sedang diteliti. Penerapan dalam hal ini adalah dengan cara memodifikasi fonem dari sebuah kata dalam lirik lagu sehingga menghasilkan kata berbeda dan merubah struktur makna di dalamnya.
Kata kunci: Fonem, Semantik, Struktural, Lagu Bali