bluuebunny/crossref_metadata_2025_split huggingface dataset:
BLUE LINES AS A MEANS OF GRAPHIC FIXATION BETWEEN WATER BODIES IN TOWN PLANNING DOCUMENTATION
Authors: Demin Mykola , Mykhailyk Olha 
Published: August 2023

In this article the purpose of the Blue Lines of Limitation as a fixation of the spatial boundaries of water bodies in the urban planning activity is considered. The peculiarities and importance of the use of Blue Lines as boundaries of the water area for maintaining urban planning discipline are indicated. Preservation of the boundaries of water areas in an urbanized environment requires the introduction of a separate urban planning restriction in the urban planning documentation. Along with the Red, Blue, Green and Yellow lines, which are already "working" in urban planning documentation, the Blue lines will graphically display the borders of the water area, regulating the regulation of urban planning activities in certain territories, which will contribute to urban planning discipline and the preservation of water ecosystems.
Blue lines can graphically fix the boundaries of the water area to limit urban planning and economic activity. Our proposal is to introduce the concept of Blue Lines into the new edition of DBN B2.2-12-202… «Planning and Development of Territories» in the following wording: "Boundaries of the coastline (cut of water) on the natural or artificially created water area of water bodies (reservoirs and water courses) - the internal boundaries of the water protection zone with defined regimes and rules of economic activity are defined by blue lines."
The development of district planning schemes, general plans of settlements, detailed plans of the territory (M 1: 25000, 1:10000, 1: 2000) graphically, with the help of blue lines, should indicate:
- cuttings of existing and artificially created reservoirs; - section of direction, channel deepening; - changing the contour of reservoirs in case of their revitalization, etc.
Fixing the spatial boundaries of the water area with the help of Blue lines will fulfill the tasks of urban planning regulations of economic activity, which will contribute to the preservation of the natural component of the water ecosystem in an urbanized environment.
To preserve and protect water bodies in an urbanized environment, effective urban planning restrictions are necessary. Urban planning restrictions contribute to the preservation of our settlements from chaotic and disharmonious construction, make the urban space safe and comfortable for residents. The designation of the Blue Lines is a tool for preserving the natural component in the urbanized environment, which will help solve the problem of balanced, rational and harmonious use of water areas and vulnerable coastal areas.
DYNAMIC LOADS IN ELASNIC ELEMENTS/ROPES OF CONSTRUCTION CRANES ANALYSIS AND OPTIMIZATION
Authors: Chovnyuk Yurii , Cherednichenko Petro , Kravchyuk Volodymyr , Ostapushchenko Olga , Kravchenko Igor 
Published: August 2023

In the study, an analysis of the dynamic model of construction cranes’ load lifting mechanism, proposed by professor Loveikyn V.S. and others, was carried out. In order to determine the dynamic loads in the elastic rope, a dynamic model is used, in which all sections of the shafts are considered rigid, and only the cable is elastic. Bringing the engine rotor masses, brake pulley, gears, drum and load to the rope branchers that are wound on the drum, allows the original complex multi-mass tech-nical system to be reduced to a simplified (two-mass) crane lifting mechanism dynamic model, which is comprehensively and in detail analyzed in transition-type modes (for example, in the start-up mode).
An established and substantiated criterion for the movement quality of the hoisting crane load mechanism, at which rope system dynamic stresses are minimized in the starting mode, as well as the dynamic coefficient for different ways of lifting the load: 1) “from the weight”; 2) “with a pick up”/ “from the base” − typical during cranes real work in cargo lifting/lowering operations (loading and unloading).
Classical variational calculus methods usage (Euler-Poisson equation) allows to determine the conditions, according to which the above-mentioned criterion for the movement quality of the load lifting mechanism can be implemented.
The movements laws of the load cargo and the drive crane mechanism are also defined, as well as law of dynamic coefficient change in time, for which there is no oscillation nature of time dependence, and the specified time functions have a mono-tonically growing character over time.
The results obtained in the work allow (when using mechatronic control systems for the cargo lifting process) prevent overloading of the crane rope system and possible emergency situations, which lead to breaks in the elastic elements of the load lifting mechanisms (i.e. ropes), and also clarify and improve the existing engineering methods of similar complex technical systems calculations in their real operation modes.
The effect of implementing Peplau’s theory of interpersonal communication on the quality of life of patients with acquired immunodeficiency syndrome
Authors: Sarami Bahareh , Hashemi-Shahraki Fatemeh , Tali Shahriar Salehi , Hasanpour-Dehkordi Ali , Reisi Hadi 
Published: August 2023

<p><strong>ABSTRACT</strong><br /><strong>BACKGROUND AND OBJECTIVES.</strong> Patients with AIDS face many problems, including problems related to treatment, social and family exclusion, high treatment costs, and drug complications, which affect the quality of life of these patients and change it. The aim was to determine the effect of the application of Peplau’s theory of interpersonal communication on the quality of life of patients with acquired immunodeficiency syndrome.<br /><strong>MATERIAL AND METHOD.</strong> This quasi-experimental study was performed on 50 AIDS patients referred to Shahrekord Behavioral Diseases Counseling Center. Simple random sampling was performed and then the sample was assigned to two groups experimental and control. The theory of therapeutic communication of Peplau on patients in the experimental group was performed individually and immediately after the intervention and three months later the quality of life questionnaire was completed in both groups. In this research, the data collection tool includes a demographic information questionnaire and a WHOQOL-BREF. The WHOQOLBREF questionnaire measures the four domains of physical health, mental health, social relationships, and environmental health with 24 questions. The chi-square or Fisher’s exact test, independent T-test and analysis of variance with repeated measurements were used to compare the quality of life of patients.<br /><strong>RESULTS.</strong> Data analysis showed no statistically significant difference in the mean score of quality of life between the experimental and control groups before the implementation of Peplau’s interpersonal communication theory (p=0.927). But after the intervention, there was a statistically significant difference in the mean score of quality of life between the two groups (p < 0.001).<br /><strong>CONCLUSION.</strong> Findings of the study show the positive effects of using Peplau’s therapeutic communication model on quality of life. Therefore, this method is recommended as an effective and cost-effective care model for all patients referred to the Shahrekord Behavioral Diseases Counseling Center.</p>
Pintando Nos Empoderamos
Authors:   Universidad de Guadalajara, Castañeda Borrayo Axayácatl , Borrayo Rodríguez Carmen Leticia 
Published: August 2023

a.	Como proceso de desarrollo a través del empoderamiento, este proyecto se orienta hacia el fortalecimiento de la participación creativa en condiciones de equidad de niñas y mujeres pintoras de la región maya del estado de Campeche, México. A partir del año 2015, el Museo comunitario de Bécal, comenzó esta iniciativa con 5 niñas pintoras (menores de edad), desde entonces, se ha logrado exposiciones de las obras en galerías de la región y actualmente, se encuentran integradas 10 pintoras (menores de edad y adultas) y 14 alumnas en formación. Se contempla generar las condiciones materiales necesarias para la formación y la extensión artística. Con un modelo de diseño de proyectos basado en Stuflebeam y Shin-kfeld (1997), Cohen y Martínez (2005), Bertranou y Caminotti (2009), así como en la Guía para la planificación local desde la perspectiva de los derechos humanos (2011), se buscará el apoyo del gobierno, la sociedad y los medios de comunicación para lograr promocionar las exposiciones de pintura, dotar de pertinencia y relevancia los contenidos y formalizar las actividades educativas.
Necessity of Fire Safety Measure Intervention among Garment Workers
Authors: Rimmi Sumaya Hossin , Jahid Md Istiak , Hossain Showlin , Chowdhury Muhammad Muniruzzaman , Mostarin Somaya , Abbas Md Golam 
Published: August 2023

Background: Providing Bangladesh with low-cost garment industries has had terrible results, including fires and building collapses that have claimed lives and injured hundreds of employees.
Objective: This study was carried out to assess the effectiveness of educational intervention programs in increasing fire safety measures among garment workers.
Methods: This was a quasi-experimental study conducted among purposively selected 160 garment workers with a semi-structured questionnaire through face-to-face interviews from 1st January to 31st December, 2021 in a factory situated in Narayanganj district.
Results: Before the educational intervention, about one-third (29.4%) of respondents had a strong awareness of fire safety; after the intervention, that number increased to 92.5%. All of them (100.0%) had clear knowledge about fire alarms and fire extinguishers after the intervention. After the intervention, the percentage of people who needed sufficient training for fire safety measures improved from 70.6% to 95.6%.
Conclusion: The results show that there is a critical need for safety intervention in the sector, which may include safety training for industry workers and health education to reduce the number of fatalities, disabilities, and societal financial burdens.
Mediscope 2023;10(2): 50-55
Cytological Diagnosis of Follicular Patterned Lesion of Thyroid Nodule and its Follow-up Histopathology
Authors: Ali Md Tokres , Roshed Md Mahabubur , Ali Mohammad , Jahan Mahmuda , Akhter Most Dalia 
Published: August 2023

The follicular patterned lesion of thyroid nodules is an exciting topic because it is not clear whether the lesion is benign or malignant. It comprises hyperplastic/adenomatoid nodules, follicular adenoma, follicular carcinoma and follicular variant of papillary carcinoma. The cytological diagnosis of atypia of undetermined significance/Follicular lesion of undetermined significance, follicular neoplasm/suspicious for follicular neoplasm and suspicious for malignancy remains controversial in terms of management. The study aimed to examine the extent of invasion of malignant lesions in follow-up histopathology diagnosed as undetermined lesions cytologically. A total of 256 cases were included in this study; among these, 199 cases were benign lesions, 15 cases were non-diagnostic and 42 cases were diagnosed either of uncertainty for malignancy with cellular atypia or malignancy. Subsequent follow-up resection and histopathology were done with 48 cases (18.75%), which comprises 1 non-diagnostic, 10 benign lesions, 21 atypia of undetermined significance/Follicular lesion of undetermined significance, 7 Follicular neoplasm/Suspicious for a follicular neoplasm, 5 suspicious for malignancy and 4 malignancies. Also, 6 Follicular variant of papillary thyroid carcinoma, 6 classic papillary carcinoma, 5 follicular carcinoma and 1 anaplastic carcinoma were diagnosed in follow-up resection histopathology of 48 cases. Thirty eight cases were of undetermined significance of malignancy with cytological features of the follicular lesion. Four Follicular variant of papillary thyroid carcinoma, 2 follicular carcinoma and 1 papillary carcinoma were diagnosed in 21 resected cases cytologically reported as Atypia of undetermined significance/Follicular lesion of undetermined significance with malignancy risk of 33.33%. Three malignancies in follicular neoplasm/suspicious for a follicular neoplasm with a risk of 42.85% and 4 malignancies in suspicious malignancy group with a risk of 80% were found. The average risk of malignancy of these three undetermined categories was reduced to 24.24% from 42.42% upon reclassification of the Follicular variant of papillary thyroid carcinoma. All the Follicular variants of papillary thyroid carcinoma diagnosed by histopathology were non-invasive regarding lymph node involvement and microvascular or capsular invasion.
Mediscope 2023;10(2): 68-77
Fatigue life of 3D-printed porous titanium dental implants predicted by validated finite element simulations
Authors: Vautrin Antoine , Aw Jensen , Attenborough Ed , Varga Peter 
Published: August 2023

Introduction: Porous dental implants represent a promising strategy to reduce failure rate by favoring osseointegration or delivering drugs locally. Incorporating porous features weakens the mechanical capacity of an implant, but sufficient fatigue strength must be ensured as regulated in the ISO 14801 standard. Experimental fatigue testing is a costly and time-intensive part of the implant development process that could be accelerated with validated computer simulations. This study aimed at developing, calibrating, and validating a numerical workflow to predict fatigue strength on six porous configurations of a simplified implant geometry.Methods: Mechanical testing was performed on 3D-printed titanium samples to establish a direct link between endurance limit (i.e., infinite fatigue life) and monotonic load to failure, and a finite element model was developed and calibrated to predict the latter. The tool was then validated by predicting the fatigue life of a given porous configuration.Results: The normalized endurance limit (10% of the ultimate load) was the same for all six porous designs, indicating that monotonic testing was a good surrogate for endurance limit. The geometry input of the simulations influenced greatly their accuracy. Utilizing the as-designed model resulted in the highest prediction error (23%) and low correlation between the estimated and experimental loads to failure (R2 = 0.65). The prediction error was smaller when utilizing specimen geometry based on micro computed tomography scans (14%) or design models adjusted to match the printed porosity (8%).Discussion: The validated numerical workflow presented in this study could therefore be used to quantitatively predict the fatigue life of a porous implant, provided that the effect of manufacturing on implant geometry is accounted for.
Case report: A complex case of valve-in-valve TAVI and left bundle branch pacing for severe aortic regurgitation with partially corrected type A aortic dissection and low ejection fraction
Authors: Mihailovič Peter Marko , Žižek David , Vitez Luka , Holc Primoz , Klokočovnik Tomislav , Bunc Matjaž 
Published: August 2023

BackgroundAortic regurgitation is a major concern following transcatheter aortic valve implantation (TAVI), as even low-grade regurgitation is associated with increased mortality. This is of particular concern to patients with pre-existing aortic disease who are at increased risk of TAVI valve slippage. Furthermore, conduction system disturbances after TAVI, namely left bundle branch block (LBBB), may have an additional detrimental effect on cardiac function.Case presentationThis report documents a successful treatment strategy in a frail patient with a bicuspid aortic valve and aortic disease after valve-sparing surgical repair in 1998, who subsequently developed aortic stenosis and underwent TAVI with an Evolut R self-expanding aortic valve. The progression of aortic disease, aortic root dilatation, and leaflet degeneration over the following years caused aortic regurgitation of the self-expanding aortic valve, resulting in left ventricular dilatation and heart failure along with LBBB and left ventricular (LV) mechanical dyssynchrony. Diagnostic workup of the patient showed persistence of the aneurysm distal to the graft with a dissection spanning the ascending aorta, arch, and terminating proximal to the aortic isthmus. After consideration by the cardiac team, a balloon-expandable valve was chosen for a valve-in-valve (ViV) procedure to provide sufficient radial force to expand the existing valve and correct the regurgitation. Due to the anatomy, a J-wire and pigtail catheter were successfully used for a safe approach and placement of the valve. Following the procedure, intermittent complete atrioventricular block was observed in addition to the pre-existing left bundle branch block, necessitating resynchronization pacing. Due to anatomical considerations, ease of placement, and the expected good level of resynchronization due to the proximal block, we opted for left bundle branch pacing, which showed improvement in left ventricular dyssynchrony and LV function at follow-up.ConclusionValve-in-valve implantation of a balloon-expandable Myval TAVI device to treat aortic regurgitation caused by slippage and right leaflet disfunction of slef valve is feasible in challenging anatomical scenarios. Left bundle branch pacing is a viable alternative to correct mechanical dyssynchrony in complex patients with LBBB and anatomical challenges necessitating resynchronization.
CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion
Authors: Norberto Sónia , Assalin Heloisa Balan , Guadagnini Dioze , Tobar Natália , Boer Patrícia Aline , Kang Min-Cheol , Saad Mario Jose Abdalla , Kim Young-Bum , Prada Patricia Oliveira 
Published: August 2023

IntroductionCdc2-like kinase (CLK2) is a member of CLK kinases expressed in hypothalamic neurons and is activated in response to refeeding, leptin, or insulin. Diet-induced obesity and leptin receptor-deficient db/db mice lack CLK2 signal in the hypothalamic neurons. The neurotransmiter gamma-aminobutyric acid (GABA) is among the most prevalent in the central nervous system (CNS), particularly in the hypothalamus. Given the abundance of GABA-expressing neurons and their potential influence on regulating energy and behavioral homeostasis, we aimed to explore whether the deletion of CLK2 in GABAergic neurons alters energy homeostasis and behavioral and cognitive functions in both genders of mice lacking CLK2 in Vgat-expressing neurons (Vgat-Cre; Clk2loxP/loxP) on chow diet.MethodsWe generated mice lacking Clk2 in Vgat-expressing neurons (Vgat-Cre; Clk2loxP/loxP) by mating Clk2loxP/loxP mice with Vgat-IRES-Cre transgenic mice and employed behavior, and physiological tests, and molecular approaches to investigate energy metabolism and behavior phenotype of both genders.Results and discussionWe showed that deletion of CLK2 in GABAergic neurons increased adiposity and food intake in females. The mechanisms behind these effects were likely due, at least in part, to hypothalamic insulin resistance and upregulation of hypothalamic Npy and Agrp expression. Besides normal insulin and pyruvate sensitivity, Vgat-Cre; Clk2loxP/loxP females were glucose intolerant. Male Vgat-Cre; Clk2loxP/loxP mice showed an increased energy expenditure (EE). Risen EE may account for avoiding weight and fat mass gain in male Vgat-Cre; Clk2loxP/loxP mice. Vgat-Cre; Clk2loxP/loxP mice had no alteration in cognition or memory functions in both genders. Interestingly, deleting CLK2 in GABAergic neurons changed anxiety-like behavior only in females, not males. These findings suggest that CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion and could be a molecular therapeutic target for combating obesity associated with psychological disorders in females.
The effects of exercise training on insulin resistance in children and adolescents with overweight or obesity: a systematic review and meta-analysis
Authors: Kazeminasab Fatemeh , Sharafifard Fatemeh , Miraghajani Maryam , Behzadnejad Nasim , Rosenkranz Sara K. 
Published: August 2023

AimThe aim of present meta-analysis was to determine the effects of exercise training (Exe) on insulin resistance (IR) and body weight in children and adolescents with overweight or obesity.MethodsPubMed, Web of Science, and Scopus were searched for original articles, published through October 2022 that included exercise versus control interventions on fasting glucose, insulin, HOMA-IR, and body weight outcomes in children and adolescents with overweight or obesity. Standardized mean differences (SMD) for fasting insulin, and weighted mean differences (WMD) for fasting glucose, HOMA-IR, body weight (BW), and 95% confidence intervals were determined using random effects models.ResultsThirty-five studies comprising 1,550 children and adolescents with overweight and obesity were included in the present meta-analysis. Exercise training reduced fasting glucose (WMD=-2.52 mg/dL, p=0.001), fasting insulin (SMD=-0.77, p=0.001), HOMA-IR (WMD=-0.82, p=0.001), and BW (WMD=-1.51 kg, p=0.001), as compared to a control. Subgroup analyses showed that biological sex, intervention duration, type of exercise training, BMI percentile, and health status (with or without diagnosed condition), were sources of heterogeneity.ConclusionExercise training is effective for lowering fasting glucose, fasting insulin, HOMA-IR, and BW in children and adolescents with overweight or obesity and could provide an important strategy for controlling IR and related factors. With clear evidence for the effectiveness of exercise interventions in this vulnerable population, it is important to determine effective approaches for increasing exercise training in children and adolescents with overweight or obesity.