bluuebunny/crossref_metadata_2025_split huggingface dataset:
Features of Mechanical Lung Ventilation During Robot-Assisted Radical Prostatectomy in Patients with Different Body Mass Index
Authors: Kazakov A. S. , Grebenchikov O. A. , Ershov A. V. 
Published: August 2023

The aim of the study. To evaluate effects of carboxyperitoneum and steep Trendenburg position on respiratory biomechanics and gas exchange indicators in patients with different body mass index (BMI) during robotic-assisted radical prostatectomy (RRP). To develop an algorithm for choosing the optimal mechanical lung ventilation (MLV) regimen. Materials and methods. The study included 141 patients with verified prostate cancer who were candidates for RPR. Participants were divided into 2 groups based on BMI: group I included 88 patients with BMI30 kg/m2, group II — 53 patients with BMI30 kg/m2. Indicators of respiratory biomechanics and gas exchange during ventilation in various modes (Volume Controlled Ventilation (VCV), Pressure Controlled Ventilation (PCV), Pressure Controlled– Inverse Ratio Ventilation (PC-IRV) were analyzed in each group at 5 consecutive stages of the procedure.Results. The key parameters evidencing the effectiveness and safety of MLV during RRP procedure did not vary significantly under various ventilation regimens in the group of patients with a BMI30 kg/m2. Whilst in obese patients the use of VCV mode resulted in a significant increase of airway peak pressure (Ppeak) already at the stage of placing them into a steep Trendelenburg position (35°), thus endangering with the development of ventilator-induced lung injury. Increased Ppeak was also accompanied by the drop in oxygen saturation and significantly lower SpO₂ values, starting from the stage of applying carboxyperitoneum and until the end of surgical intervention.Conclusion. In non-obese patients, there’s no particular ventilator regimen that is crucial for achieving the safety and effectiveness of RRP anesthesia management, all regimens can be used. In patients with BMI30 kg/m2 PCV regimen and PC-IRV with inhalation/exhalation ratio of 1.5:1 can be considered as the optimal strategy for MLV during anesthesia for RRP surgery.
Developmental Trajectories of Autism
Authors: Fountain Christine , Winter Alix S. , Cheslack-Postava Keely , Bearman Peter S. 
Published: August 2023

OBJECTIVES
The goal of this study was to describe the typical, longitudinal, developmental trajectories of communication and social functioning in individuals with autism spectrum disorder from childhood through adulthood and to determine the correlates of these trajectories.

METHODS
Children with autism spectrum disorder who were born in California from 1992 through 2016 and enrolled with the California Department of Developmental Services were identified. Subjects with &lt;4 evaluations in the database were excluded, resulting in a sample of 71 285 individuals. Score sequences were constructed based on evaluative items for communication and social functioning. Typical trajectories were identified using group-based latent trajectory modeling, and logistic regression was used to determine the odds of classification into a social adolescent decline trajectory by individual-, family-, and zip code-level factors.

RESULTS
Six typical patterns of communication functioning and 7 typical patterns of social functioning were identified. Whereas the majority of autistic individuals exhibit improved communication functioning as they age, the majority of individuals exhibit steady social functioning. A small group of individuals (5.0%) exhibits high social functioning in childhood that declines in adolescence. Membership in this adolescent decline group is associated with maternal non-Hispanic white race and ethnicity, female sex, moderate levels of maternal education, lower zip code-level median home values and population density, and higher zip code-level inequality.

CONCLUSIONS
Most autistic individuals show improved communication and social functioning as they age, but not all do. Trajectory group membership is correlated with socioeconomic status. Future research should investigate what drives these correlations.
KARAKTERISTIK BIOLOGI CUMI-CUMI DI PERAIRAN LAUT JAWA
Authors: Puspasari Reny , Triharyuni Setiya 
Published: August 2023

Cumi-cumi merupakan hasil tangkapan sampingan bagi sektor perikanan di Laut Jawa, namun memiliki nilai ekonomi cukup penting. Pengamatan ini bertujuan untuk mengetahui aspek biologi cumi-cumi mencakup komposisi jenis, morfometrik, rasio kelamin dan tingkat kematangan gonad yang tertangkap di perairan utara Jawa di sekitar periaran Rembang, Cirebon dan Belanakan Subang. Ada empat jenis cumi-cumi ditemukan dalam pengamatan ini yaitu Loligo duvauceli sebagai jenis dominan, disusul oleh L. edulis, L. chinensis dan L. singhalensis. Hubungan panjang mantel dan berat jenis L. duvauceli menunjukkan nilai koefisien pertumbuhan b sebesar 2,003 untuk jantan dan 1,942 untuk betina. Hasil tangkapan individu jantan pada bulan Juni dan Oktober lebih tinggi. Pengamatan tingkat kematangan gonad menunjukkan bahwa cumi-cumi memijah sepanjang tahun. Karakteristik biologi cumi-cumi di perairan Rembang tidak berbeda nyata dengan cumi-cumi di perairan Cirebon dan Subang, serta memiliki karakteristik yang sama dengan cumi-cumi yang tertangkap di Selat Alas dan perairan India, kecuali waktu puncak pemijahan yang lebih lambat di perairan Rembang dan Cirebon dibandingkan dengan di lokasi lainnya.Squid are not the main target of cath fiesheries in the Java Sea, but it has high economic value. The aim of this observation is to study the biological aspect of squid, such as species composition, morfometric, sex rasio and maturity which were caught in Rembang, Cirebon and Subang. There are four species of squid were recorded during sampling dominated by Loligo duvauceli while the others were L. edulis, L. chinensis and L. singhalensis. The Length-weight relatioship of L.duvauceli showed that the growth coeffiicient were 2,003 and 1,942 for male and female respectively. Male were found common in June and October compare to female. Squid were spawned all over the year. There were no significant differences among squid caught in the waters around Rembang, Cirebon and Subang, and it seems also the same biological characters with squid in Alas Strait Nusa Tenggara Barat (NTB) and Indian waters, but the peak of spawning season in Rembang and Cirebon was late than others.
Seguridad y Salud en el Trabajo una innovación constante
Authors: Quiroz Rubiano Monica Maria , Zamora Romero Derly 
Published: August 2023

La Seguridad y Salud en el Trabajo es un tema que toma cada vez más importancia dentro de las organizaciones, por lo tanto, hablar de innovación en este campo es elemento clave y diferenciador en las organizaciones, que puede contribuir a reducir el riesgo de accidentes y enfermedades laborales, así como aumentar la competitividad de la empresa y por ende mejorar su calidad de vida; la innovación puede incluir medidas organizativas hasta nuevos sistemas de control de los peligros, algunas estrategias de innovación están orientadas a Introducir nuevas tecnologías de seguridad.
Evaluation of GLP-2 receptor expression in gastrointestinal neuroendocrine tumors
Authors: NAMLI KOÇ Şule , SAĞOL Özgül , AKARSU Mesut 
Published: August 2023

Evaluation of GLP-2 receptor expression in gastrointestinal neuroendocrine tumors
Background and Aims: Neuroendocrine tumors arise from cells of the neuroendocrine system. These cells show both nerve and endocrine cell characteristics and can be found in many organs in the body. GLP-1 and GLP-2 are released from intestinal L cells in a 1:1 ratio following food intake. GLP-2 receptor recognizes GLP-2. GLP-2 receptor mRNA transcripts have been detected in the stomach, small and large intestine, brain, and lung. The proliferative effect of GLP-2 has been demonstrated in mice, rats, pigs, and humans by administering exogenous GLP-2. The objective is to evalaute the relation between gastroenteropancreatic neuroendocrine tumors and glukagon like peptid-2 and GLP-2 receptor. Materials and Methods: The patients, who were pathologically diagnosed with gastroenteropancreatic neuroendocrine tumor between 2006-2009 were included in the study. There were 47 patients (27 females, 20 males, avarage age: 54 ± 15.5) in the study. There were also 46 control group patients (25 females, 21 males, avarage age: 57.5 ± 14.8). Pathological tissue blocks prepared on poly-L-lysine microscope slides were stained by GLP-2 receptor antibody (1:100 - 1:200, 1 mg/ml) immunohistochemical stain. Results: GLP-2 receptor positivity of colon neuroendocrine tumor group was 30% (4/13) and colon control group was %100. GLP-2 receptor positivity of pancreas neuroendocrine tumor group was 25% (3/12) while it was 100% in pancreas control group. The comparison of colon neuroendocrine tumor and control group showed significant difference (p: 0.003). The comparison of pancreas neuroendocrine tumor and control group also showed statistically significant difference (p < 0.001). The comparison of gastric neuroendocrine tumor with the control yielded comparable results (p: 0.22). Conclusions: We concluded that GLP-2 receptor cannot be as useful as somatostatin receptors in diagnosis and treatment of these tumors. More studies are needed on this subject with different methods.
Early diagnosis of placenta accreta in case of mid trimester postabortal haemorrhage with previous 3 cesarean sections
Authors: Gautam Arti , Malik Neeru , Jain Sandhya 
Published: August 2023

: To know the risk and management of postabortal haemorrhage in patients with previous caesarean delivery to prevent maternal mortality. : Placenta accreta is an emergency life threatening obstetric situation may also complicate first trimester and midtrimester abortion and encountered as profuse vaginal bleeding and difficulty in placenta removal at delivery. The incidence of placenta accreta increased from 1 in 30,000 pregnancies in 1960 to 1 in 533 pregnancies in 2000. Placenta accreta developed in 55 of 590 women with placenta previa and 7 of 156080 without placenta previa. Increased incidence of caesarean increases the incidence of placenta accreta. Multiple caesarean deliveries are largest risk factor for placenta accreta. On the basis of a high risk factor, suspected case of placenta accreta spectrum, must be diagnose and be in charge of a multidisciplinary team with better maternal and fetal outcome. A 36 years old patient, P3L3A1 had prior 3 LSCS with retained placenta with profuse bleeding per vaginum with history of expulsion of fetus (18 week) on the way to hospital, presented to labor room. Patient was unbooked and uninvestigated. Initial resuscitation done along with oxytocic given but no sign of placental separation was there and bleeding was continued. On the basis of torrential bleeding and history of previous three caesarean deliveries, patient is immediately shifted to the operation theatre for exploratory laparotomy in view or provisional diagnosis of a morbidly adherent placenta with torrential haemorrhage. On laparotomy, the anterior surface of lower uterine segment of uterus accompanied by numbers of engorged blood vessels. Bladder was spared. Decision of exploratory laparotomy taken into consideration of morbidly adherent placenta, and procedure was ended with Subtotal hysterectomy, haemostasis achieved. 2 units PCV transfused intraoperatively and patient was shifted to intensive care unit for observation postoperatively. Her postoperative duration was uneventful; she got discharged on postoperative day6 under satisfactory condition. The specimen was sent for histopathological examination. Vigilant monitoring and timely intervention in obstetric emergencies can avoid maternal mortality. We wish to highlight the vigilant monitoring and timely decision, active collaboration by multidisciplinary team improve outcomes in patient of postabortal haemorrhage in midtrimester with previous caesarean delivery with placenta accreta spectrum.
The Prevalence of Obstructive Sleep Apnea in Bariatric Surgery Patients
Authors: ANNAKKAYA Ali Nihat , GÜLEÇ BALBAY Ege , PEHLİVAN Mevlüt , BALBAY Öner 
Published: August 2023

Objective: Obesity is one of the most important risk factors and also consequences of obstructive sleep apnea (OSA). Weight loss and positive airway pressure therapy are the main approaches in the treatment of OSA. In this study, it was aimed to evaluate the prevalence of OSA in obesity patients scheduled for bariatric surgery.
Methods: In the University Hospital Obesity Center, 141 consecutive patients who were candidates for bariatric surgery in 2015 were clinically evaluated preoperatively for sleep-related respiratory disorders. Preoperative polysomnographic examination was recommended to all cases.
Results: Of 141 bariatric surgery candidates with a mean age of 37±10 years, and 103 (73%) were female. The mean body mass index of the cases was 46.9±6.4 kg/m2. Among the major symptoms of OSA, snoring was present in 119 (84.4%), daytime sleepiness in 63 (44.7%) and witnessed apnea in 49 (34.8%) patients. OSA was detected because AHI>5/hour was found in 75.7% (84/111) of the patients who accepted the polysomnographic evaluation. 24.3% (27/111) of the cases who underwent polysomnography had non OSA, 29.7% (33/111) mild OSA, 17.1% (19/111) moderate OSA, and 28.8% (32 /111), severe OSA was detected. AHI was positively correlated with age (p=0.003), neck and waist diameter (p
Pandemia trouxe oportunidades para mais inclusão na ciência
Authors: Oliveira Monique Batista de , Barata Germana Fernandes , Hafiz Mariana , Marshall Melanie Benson , Pinfield Stephen 
Published: August 2023

Introdução: A pandemia da Covid-19 produziu um grande volume de dados científicos e fomentou práticas abertas de ciência em função do compartilhamento de dados para o controle do vírus Sars-CoV-2. Tal cenário gerou oportunidades para o movimento da Ciência Aberta (CA). Objetivo: O intuito deste artigo é mapear as narrativas circulantes sobre práticas de CA durante a pandemia – com destaque aos debates sobre acesso público ao conhecimento e a práticas e valores características de Equidade, Diversidade e Inclusão (EDI). Metodologia: Realizou-se análise documental e temática de 30 artigos científicos, notícias na imprensa, posts de blogs e materiais institucionais publicados em português obtidos mediante busca por palavras-chave no SciELO, Google e bibliotecas da Câmara e do Senado. Resultados: Observou-se que 36,6% (11) dos documentos mencionaram valores de EDI, enquanto 70% (21) incluíram discussões sobre acesso público e universal ao conhecimento. Os textos poderiam apresentar ambas as temáticas, sendo contabilizados tanto na categoria de EDI quanto de acesso público. Da amostra, 23% (7) não mencionaram nenhuma dessas duas categorias e 77% apresentaram ao menos uma delas. Conclusão: De modo geral, o uso da ciência aberta foi associado à rápida produção de respostas para a pandemia, o que levanta questões sobre a continuidade de práticas abertas em períodos em que essa urgência não esteja presente. Quanto ao debate sobre EDI, embora ainda incipiente, a pandemia apresenta oportunidades de coprodução do conhecimento e práticas mais inclusivas — com experiências de debates públicos em tempo real da construção de evidências.
The Principles of Knee Joint Preservation: Operative Treatment Strategies
Authors: Kraeutler Matthew J. , McCulloch Patrick C. , Sherman Seth L. , Vidal Armando F. 
Published: August 2023

➤ Joint alignment, meniscal status, and ligament stability are codependent factors involved in knee joint preservation, and any injury or imbalance can impact the knee articular cartilage status and can result in adverse clinical outcomes.➤ Cartilage preservation procedures in the knee will not result in optimal outcomes if there is joint malalignment, meniscal deficiency, or ligamentous instability.➤ Lower-extremity varus or valgus malalignment is a risk factor for the failure of an anterior cruciate ligament (ACL) reconstruction. It represents an indication for a high tibial osteotomy or distal femoral osteotomy in the setting of failed ACL reconstruction, and may even be considered in patients who have an initial ACL injury and severe malalignment.➤ An elevated posterior tibial slope increases the risk of failure of ACL reconstruction, whereas a decreased posterior tibial slope increases the risk of failure of posterior cruciate ligament reconstruction.
Long-Term Follow-up (14 to 25 Years) Following Closed Reduction and Early Movement for Simple Dislocation of the Elbow
Authors: Mackinnon Thomas , Samuel Thomas D. , Hayter Edward , Lee George , Huntley Daniel , Hardman John , Anakwe Raymond E. 
Published: August 2023

Background:
We have previously reported on the midterm outcomes after a nonoperative protocol to treat simple dislocations of the elbow that included a short period of splinting followed by early movement. We have now performed extended follow-up of the original patient group from the prior study to determine whether the excellent results that previously had been reported were maintained in the long term and also to determine the rate of and need for any late surgical intervention.

Methods:
We attempted to contact all of the patients from the original study group. We requested that they complete the Oxford Elbow Score (OES) survey, the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, and a validated patient satisfaction questionnaire. Patients also were requested to attend a face-to-face assessment to have a clinical examination that included neurovascular, range-of-motion, and ligamentous stability assessments.

Results:
Seventy-one patients from the original patient group agreed to participate in the new study. The mean duration of follow-up was 19.3 years. At the time of the final follow-up, patients reported excellent functional outcome scores and a preserved functional range of movement in the injured elbow. The mean OES was 91.6 points, the mean DASH score was 5.22 points, and the mean satisfaction score was 90.9 points. None of the patients had undergone delayed or secondary surgery for instability during the interval period.

Conclusions:
This study demonstrated that the original excellent outcomes following treatment with a protocol of a short period of splinting and early movement remained excellent and were maintained into the very long term.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Supine Lobenhoffer Approach Optimizes PCL Reconstruction with Tibial Inlay in Knee Dislocations
Authors: Doan Hoi , Holy Tomas , Richter Dustin L. , Campos Tulio , Held Michael , Del Castillo Juan , Schenck Robert C. 
Published: August 2023

Case:
A 47-year-old man suffered a knee dislocation while skiing with associated damage to the anterior cruciate, posterior cruciate, medial collateral, and medial patellofemoral ligaments. The patient underwent a multiple-ligament knee reconstruction using the supine Lobenhoffer approach, which resulted in remarkable outcomes that persisted throughout the 56-month follow-up period.

Conclusion:
The utilization of this approach can prevent inappropriate graft tension and iatrogenic damage, reduce surgical time, and minimize airway complications by eliminating the need for the prone position. Optimizing these factors enhances the patient's chances for long-term outcomes; thus, surgeons should consider this approach in managing multiple-ligament knee injuries.
Watchful Eye Prevents Catastrophe in Case of Malignant Hyperthermia
Authors: Brenner Joseph , Cage Emily , Andrews Kyle 
Published: August 2023

Case:
A 49-year-old woman presented with a displaced left posterior wall acetabular fracture-dislocation and a left comminuted intra-articular distal radius fracture sustained in a motor vehicle accident. Fifteen minutes after anesthesia induction for operative fixation of the fractures, the patient experienced severe hypertension, increased end-tidal carbon dioxide, and fever. A diagnosis of malignant hyperthermia (MH) was made before incision. The patient was medically stabilized, and her acetabular fracture-dislocation was placed in skeletal traction until she was deemed fit for surgery 4 days later.

Conclusion:
This case report highlights the importance of early recognition of MH and perioperative management.
The Value of Computer-Assisted Navigation for Glenoid Baseplate Implantation in Reverse Shoulder Arthroplasty
Authors: Velasquez Garcia Ausberto , Abdo Glen , Sanchez-Sotelo Joaquin , Morrey Mark E. 
Published: August 2023

Background:
Glenoid baseplate malpositioning during reverse total shoulder arthroplasty can contribute to perimeter impingement, dislocation, and loosening. Despite advances in preoperative planning, conventional instrumentation may lead to considerable inaccuracy in implant positioning unless patient-specific guides are used. Optical navigation has the potential to improve accuracy and precision when implanting a reverse shoulder arthroplasty baseplate. This systematic review aimed to analyze the most recent evidence on the accuracy and precision of glenoid baseplate positioning using intraoperative navigation and its potential impact on component selection and surgical time.

Methods:
We conducted a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. The PubMed, Scopus, and EMBASE databases were queried in July 2022 to identify all studies that compared navigation vs. conventional instrumentation for reverse shoulder arthroplasty. Data of deviation from the planned baseplate version and inclination, the use of standard or augmented glenoid components, and surgical time were extracted. Quantitative analysis from the included publications was performed using the inverse-variance approach and Mantel-Haenszel method.

Results:
Of the 2,048 records identified in the initial query, only 10 articles met the inclusion and exclusion criteria, comprising 667 shoulders that underwent reverse total shoulder arthroplasty. The pooled mean difference (MD) of the deviation from the planned baseplate position for the clinical studies was −0.44 (95% confidence interval [CI], −3.26; p = 0.76; I2 = 36%) for version and −8.75 (95% CI, −16.83 to −0.68; p = 0.02; I2 = 83%) for inclination, both in favor of navigation. The odds ratio of selecting an augmented glenoid component after preoperative planning and navigation-assisted surgery was 8.09 (95% CI, 3.82-17.14; p < 0.00001; I2 = 60%). The average surgical time was 12 minutes longer in the navigation group (MD 12.46, 95% CI, 5.20-19.72; p = 0.0008; I2 = 71%).

Conclusions:
Preoperative planning integrated with computer-assisted navigation surgery seems to increase the accuracy and precision of glenoid baseplate inclination compared with the preoperatively planned placement during reverse total shoulder arthroplasty. The surgical time and proportion of augmented glenoid components significantly increase when using navigation. However, the clinical impact of these findings on improving prosthesis longevity, complications, and patient functional outcomes is still unknown.

Level of Evidence:

Level III, systematic review and meta-analysis. See Instructions for Authors for a complete description of levels of evidence.