bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scholarship on LGBTQIA+ migrants in the social work field: A scoping review
Authors: Matharu Gurleen Kaur , Tri Thomas , Gonzalez Benson Odessa , Palova Katerina , Kassan Anusha 
Published: January 2025

Abstract
In social work and related practice fields, studies tend to treat LGBTQIA+ and migrant communities as distinct groups, overlooking the unique challenges faced by those at their intersection. This study uses an intersectional lens to examine social work scholarship on LGBTQIA+ migrants in order to map trends and identify gaps. We examined scholarship along various dimensions, including (1) geography, temporality, and methodology; (2) migrant and gender and sexuality identities; and (3) a range of topics. Findings suggest that literature is skewed towards health and mental health as a topic, qualitative methods, and the Global North as the location of first authors and research sites. Economic migrants receive more attention than vulnerable groups such as asylum seekers and undocumented migrants. Regarding sexual and gender identities, the bulk of literature is focused on men who have sex with men, followed by gay, lesbian, and bisexual identities. Also, the number of identities examined has greatly increased over time, while LGBTQIA+ migrant youth emerged as understudied. Findings in this scoping review point to heightened intersectional perspectives in the study of LGBTQIA+ migrants in the social work field.
A review of secondary intention healing in dermatology and dermatological surgery: part 1
Authors: Potluru Aparna , Pawlik Olga , Barlow Richard , Veitch David , Wernham Aaron 
Published: January 2025

Abstract
Secondary intention healing (SIH) describes wounds healing from the base upwards, without direct closure. This starts with granulation of the wound, followed by re-epithelialization and contraction. The surgeon and patient need to weigh up the advantages and disadvantages of SIH vs. other reconstruction methods. There are limited studies directly comparing SIH with skin grafts; however, SIH looks to be a robust alternative in specific settings. Well-established sites for SIH include concave areas such as the nose, eye, ear and temple, as these areas give rise to the best cosmetic outcomes. However, SIH has proven to be a successful repair method in several convex locations, including the dorsa of the hands, digital extremities, scalp, lips and eyelids. SIH can be supplemented by other surgical techniques, including purse-string sutures and postoperative de-epithelialization.
Safety, Efficacy, and Pharmacokinetics of Daily Optimized Doses of Rifampicin for the Treatment of Tuberculosis: A Systematic Review and Bayesian Network Meta-Analysis
Authors: Espinosa-Pereiro Juan , Aguiar Ana , Nara Eva , Medina Angelica , Molinas Gladys , Tavares Margarida , Tortola Teresa , Ghimire Samiksha , Alfenaar Jan-Willem C , Sturkenboom Marieke G G , Magis-Escurra Cecile , Sánchez-Montalva Adrián , Barros Henrique , Duarte Raquel 
Published: January 2025

Abstract

Background
Higher than standard doses of rifampicin could improve the treatment outcome of drug-susceptible tuberculosis (TB) without compromising the safety of patients.

Methods
We performed a systematic review of prospective clinical studies including adults with pulmonary and extrapulmonary TB receiving rifampicin doses above 10 mg/kg/day. We extracted the data on overall adverse events (AE), hepatic AE, sputum culture conversion (SCC) at week 8, recurrence, mortality, and pharmacokinetics. We performed a Bayesian network meta-analysis (NMA) using a random-effects model.

Results
In 19 studies, 2033 out of 3654 participants received rifampicin doses higher than 10 mg/kg/day. The NMA showed an increased risk of overall and hepatic AE for the 40 mg/kg/day dose (risk ratio [RR] 4.8, 95% credibility interval [CrI]: 1.1, 25, and 15.00; 95% CrI: 1.1, 58.0, respectively), but no other doses, including 50 mg/kg/day showed such an increase. Increasing doses improved sputum culture conversion at week 8 (RR 1.3, 95% CrI: 1.1, 1.7 for SCC with 35 mg/kg/day).

Conclusions
Optimal doses of rifampicin may be between 25 and 35 mg/kg/day, but should be tailored at the individual or, at least, at the population level.
Impact of COVID-19 pandemic on the incidence and prevalence of postural orthostatic tachycardia syndrome
Authors: Dulal Dharmindra , Maraey Ahmed , Elsharnoby Hadeer , Chacko Paul , Grubb Blair 
Published: January 2025

Abstract

Background
Individuals recovering from COVID-19 infection have reported experiencing symptoms of postural orthostatic tachycardia syndrome (POTS). These observations have raised concerns about COVID-19 as a significant precipitating factor in the development of post-viral POTS. Given the increasing number of POTS cases reported after COVID-19, we sought to examine the baseline characteristics of POTS patients before and after COVID-19.

Methods
We conducted an interrupted time series analysis on data obtained from the TriNetX database, which included a cohort of 65 141 065 patients aged 18 and older across 64 healthcare organizations. Monthly data on incidence rates (IR), incidence cases (IC), and prevalence cases (PC) of POTS were collected from January 2018 to June 2024, with 1 March 2020 defined as the cutoff date for pre- and post-COVID analysis.

Results
There was a significant increase in the IR of POTS post-COVID (P &lt; 0.0001), with the IR increasing from 1.42/1000 000 to 20.3/1000 000 cases per person-year. Similarly, the monthly IC trend showed a significant rise from 4.21 to 22.66 cases (P &lt; 0.001). The month-to-month prevalence showed an initial decline after COVID with a robust increase starting January 2023. Additionally, the prevalence of autonomic nervous system disorders and related comorbidities significantly decreased in the post-COVID cohort.

Conclusion
Our findings demonstrate a significant increase in the incidence of POTS following the COVID-19 pandemic, suggesting a potential association between COVID-19 infection and the development of post-viral POTS. Future research should explore the underlying mechanisms and treatment strategies for POTS in the context of post-COVID recovery.
Telomere-to-telomere genome and resequencing of 254 individuals reveal evolution, genomic footprints in Asian icefish, Protosalanx chinensis
Authors: Zhou Yanfeng , Wang Chenhe , Wang Binhu , Xu Dongpo , Zhang Xizhao , Ge You , Jiang Shulun , Tang Fujiang , Chen Chunhai , Li Xuemei , Jian Jianbo , You Yang 
Published: January 2025

Abstract
The Asian icefish, Protosalanx chinensis, has undergone extensive colonization in various waters across China for decades due to its ecological and physiological significance as well as its economic importance in the fishery resource. Here, we decoded a telomere-to-telomere (T2T) genome for P. chinensis combining PacBio HiFi long reads and ultra-long ONT (nanopore) reads and Hi-C data. The telomere was identified in both ends of the contig/chromosome. The expanded gene associated with circadian entrainment suggests that P. chinensis may exhibit a high sensitivity to photoperiod. The contracted genes’ immune-related families and DNA repair associated with positive selection in P. chinensis suggested the selection pressure during adaptive evolution. The population genetic analysis reported the genetic diversity and genomic footprints in 254 individuals from 8 different locations. The natural seawater samples can be the highest diversity and different from other freshwater and introduced populations. The divergent regions’ associated genes were found to be related to the osmotic pressure system, suggesting adaptations to alkalinity and salinity. Thus, the T2T genome and genetic variation can be valuable resources for genomic footprints in P. chinensis, shedding light on its evolution, comparative genomics, and the genetic differences between natural and introduced populations.
Pseudo-prospective earthquake forecasting experiment in Italy based on temporal variation of the b-value of the Gutenberg–Richter law
Authors: Biondini E , D'Orazio F , Lolli B , Gasperini P 
Published: January 2025

SUMMARY
We present the BVAL method, designed to forecast potentially damaging earthquakes (Mw ≥ 5.0) in Italy based on temporal variations of the b-value of the Gutenberg–Richter frequency–magnitude distribution. The b-value is used as an indicator of stress within the Earth's crust, with lower b-values associated with higher stress levels and an increased likelihood of significant seismic events. This method issues alarms when the b-value falls below a critical threshold. It is optimized using the HOmogenized instRUmental Seismic catalogue data from 1990 to 2004 and validated pseudo-prospectively using data from 2005 to 2022. Our analysis uses the recently developed b-positive (b+) method to compute the b-value from magnitude differences, providing resilience against data incompleteness. We compare the performance of the BVAL method with two established models: the Epidemic Type Aftershock Sequence (ETAS) model, which forecasts earthquake rates based on the epidemic principle that each shock triggers subsequent shocks, and the FORE model, which relies on the occurrence of strong foreshocks. Additionally, we evaluate two ensemble models that combine BVAL and FORE through additive (EADD) and multiplicative (EMUL) strategies to balance false alarms and missed events. The EADD model declares an alarm when either BVAL or FORE signals it, while the EMUL model triggers alarms only when both methods agree. We assess the predictive efficiency of these models using the area skill score, derived from Molchan diagrams, which plot the miss rate against the fraction of space-time occupied by alarms. Our results demonstrate that BVAL is less effective than FORE and ETAS at high space-time fractions, but it outperforms ETAS at low fractions ($\tau \ $ &lt; 2–4 per cent), indicating its potential utility in scenarios where minimizing false alarms is critical. This comprehensive comparison highlights the strengths and limitations of each method, suggesting that integrating multiple forecasting strategies can enhance the reliability of earthquake preparedness and response efforts in Italy.
Honeybee toxicity of pesticides used in United States maize and soybean production, 1998–2020
Authors: Kniss Andrew R , De Stefano Andrea , Arnold Elyssa , Douglass Cameron , Myers Clayton , Paisley-Jones Claire , Ranville Michelle 
Published: January 2025

Abstract
Pesticides are widely used around the world and have demonstrated benefits to crop production. However, pesticides have also been associated with negative impacts to nontarget organisms, including pollinators. Here, we combined pesticide usage and toxicity data to create a toxicity index, which shows that pesticide hazard to honeybees (Apis mellifera) has changed substantially in U.S. maize (Zea mays) and soybean (Glycine max) production between 1998 and 2020. To reduce potential risks to honeybees and increase the eco-efficiency of crop production, efforts should be made to refine management strategies for pests that contribute most to the honeybee toxicity index. In maize, Coleoptera and Lepidoptera pests drive pesticide usage most responsible for hazard to honeybees, although the relative hazard from targeting those pests has decreased over time. In soybean, hemipteran pests were the largest relative contributor to insecticide honeybee hazard. Specific pests that contributed to honeybee toxicity hazard included corn rootworm species (Diabrotica spp.), silk-eating insects, and cutworms in maize, and stink bugs (family Pentatomidae) and aphid species (Family Aphididae) in soybean. We combined crop yield data with the toxicity index to quantify the eco-efficiency, a measure of crop yield per unit of toxicity hazard. While crop yield for both maize and soybean increased steadily throughout the study period, eco-efficiency decreased in both crops between 2012 and 2020, suggesting increases in crop yield have failed to keep pace with increases in insecticide hazard to honeybees.
Efficacy of cleaning, disinfection, and sterilization modalities for addressing infectious drug-resistant fungi: a review
Authors: Garvey Mary , Kremer Terra A , Rowan Neil J 
Published: January 2025

Abstract
This is a timely and important review that focuses on the appropriateness of established cleaning, disinfection, and sterilization methods to safely and effectively address infectious fungal drug-resistant pathogens that can potentially contaminate reusable medical devices used in healthcare environment in order to mitigate the risk of patient infection. The release of the World Health Organization (WHO) fungal priority pathogen list (FPPL) in 2022 highlighted the public health crisis of antimicrobial resistance (AMR) in clinically relevant fungal species. Contamination of medical devices with drug-resistant fungal pathogens (including those on the FPPL) in healthcare is a rare event that is more likely to occur due to cross-transmission arising from lapses in hand hygiene practices. Established disinfection and sterilization methods decontaminate fungal pathogens on single-use and reusable medical devices; however, there are assumptions that reusable devices destined for semi-critical use are appropriately cleaned and do not harbour biofilms that may undermine the ability to effectively decontamination these type devices in healthcare. International standards dictate that manufacturer’s instructions for use must provide appropriate guidance to healthcare facilities to meet safe reprocessing expectations that include addressing drug-resistant fungal pathogens. Increased environmental monitoring and vigilance surrounding fungal pathogens in healthcare is advised, including adherence to hand hygiene/aseptic practices and appropriate cleaning encompassing the simplification of reusable device features for ‘ease-of-reach’. There are emereging opportunities to promote a more integrated multiactor hub approach to addressing these sophisticated challenges, including future use of artificial intelligence and machine learning for improved diagnostics, monitoring/surveillance (such as healthcare and wastewater-based epidemiology), sterility assurance, and device design. There is a knowledge gap surrounding the occurrence and potential persistence of drug-resistant fungal pathogens harboured in biofilms, particularly for ascertaining efficacy of high-level disinfection for semi-critical use devices.
Assessing the lethal effects of pesticide residue exposure on beneficial parasitoids and their host, Halyomorpha halys (Stål) (Hemiptera: Pentatomidae)
Authors: Luo Zheng-Yu , Gao Li-Ping , Li Wen-Jing , Chen Ju-Hong , Ali Muhammad Yasir , Zhang Feng , Li Feng-Qi , Wang Xiang-Ping , Zhang Jin-Ping 
Published: January 2025

Abstract
Chemical control is currently the main strategy for managing brown marmorated stink bug, Halyomorpha halys (Stål). However, chemical pesticides can harm nontarget species, including natural enemies of H. halys. Pesticides with high toxicity to H. halys and low toxicity to its parasitoids need to be identified to support H. halys management. This is not only for natural biological control but also for preemptive classical biological control of H. halys by parasitoids. Here, we assessed the contact toxicity of residues of eight insecticides against H. halys and three of its main parasitoid species (Anastatus japonicus Ashmead (Hymenoptera: Eupelmidae), Trissolcus japonicus Ashmead (Hymenoptera: Scelionidae), Trissolcus cultratus Mayr (Hymenoptera: Scelionidae)). This study aims to provide valuable insights for preemptive classical biological control of H. halys using these parasitoids. Our results showed that A. japonicus exhibited higher tolerance to the tested pesticides, while T. japonicus was the most sensitive species. Among the pesticides, chlorantraniliprole had the lowest overall impact on all three parasitoid species. Additionally, acetamiprid, azadirachtin, and rotenone were found to be harmless to A. japonicus. Acetamiprid, however, was slightly harmful to T. cultratus. The remaining pesticides showed moderate to significant harmful effects on the parasitoids. For H. halys adults and fifth instars, the pesticides tested caused no mortality within the 24 h exposure. However, young nymphs were susceptible to the tested pesticides. Fenpropathrin had the highest toxicity to H. halys, killing 83.3%, 52.8%, and 19.4% of second, third, and fourth instars in a 24 h exposure. Fenpropathrin, acetamiprid, cyfluthrin, azadirachtin, and dinotefuran were all slightly harmful to the first instar nymphs. The other pesticides were harmless to H. halys in a 24 h exposure. Halyomorpha halys mortality increased with the contact time with the residue. Mortality of fourth and fifth instars of H. halys was &gt;70% for fenpropathrin, cyfluthrin, dinotefuran, abamectin-aminomethyl, and acetamiprid if exposure continued for 7 d. Acetamiprid was effective in controlling H. halys nymphs but exhibited varying levels of toxicity towards the three tested parasitoid species, depending on the residue age and exposure time. Azadirachtin showed lower overall toxicity to beneficial insects, suggesting that these materials could be used to manage H. halys while minimizing harm to key beneficial species.
A comparison of shrinkage estimators of the cosmological precision matrix
Authors: Looijmans Marnix J , Wang Mike (Shengbo) , Beutler Florian 
Published: January 2025

ABSTRACT
The determination of the covariance matrix and its inverse, the precision matrix, is critical in the statistical analysis of cosmological measurements. The covariance matrix is typically estimated with a limited number of simulations at great computational cost before inversion into the precision matrix; therefore, it can be ill-conditioned and overly noisy when the sample size n used for estimation is not much larger than the data vector dimension. In this work, we consider a class of methods known as shrinkage estimation for the precision matrix, which combines an empirical estimate with a target that is either analytical or stochastic. These methods include linear and non-linear shrinkage applied to the covariance matrix (the latter represented by the so-called NERCOME estimator), and the direct linear shrinkage estimation of the precision matrix which we introduce in a cosmological setting. By performing Bayesian parameter inference and using metrics like matrix loss functions, the Kullback–Leibler divergence and the eigenvalue spectrum, we compare their performance against the standard sample estimator with varying sample size n. We have found the shrinkage estimators to significantly improve the posterior distribution at low n, especially for the linear shrinkage estimators either inverted from the covariance matrix or applied directly to the precision matrix, with an empirical target constructed from the sample estimate. Our results are particularly relevant to the analyses of Stage-IV spectroscopic galaxy surveys such as the Dark Energy Spectroscopic Instrument and Euclid, whose statistical power can be limited by the computational cost of obtaining an accurate precision matrix estimate.
Photometry of (162173) Ryugu and its artificial crater as inferred by Hayabusa2/ONC images
Authors: Longobardo A , Angrisani M , Palomba E , Dirri F , Yokota Y , Kouyama T ,   the Hayabusa2/ONC Team
Published: January 2025

ABSTRACT
The JAXA/Hayabusa2 rendezvoused with the (162 173) Ryugu asteroid from June 2018 to November 2019, performing an artificial impact experiment on 5th April 2019. The goal of this work is to study the photometric properties’ variation of the target area (latitude 7–10°N; longitude 303–305°E) after the artificial impact experiment. This is done by applying an empirical method based on the statistical analysis of the Optical Navigation Camera (ONC)’s data set (in particular, of the v band, centred at 0.55 $\mu$m), similar to that applied to other asteroids explored by space missions and to the NIRS3 data set of Ryugu. The method was firstly applied on the entire data set acquired between March and April 2019, covering most of the Ryugu surface. The retrieved average phase function of Ryugu is very similar to that obtained on the NIRS3 data set, according to the similar visible and near-infrared albedo values. Nevertheless, this phase function is flatter than other asteroids belonging to the same Ryugu taxonomic class. This can be attributed to the higher spatial resolution of Hayabusa2 observations, which flattens the phase function of dark asteroids by minimizing the effects of shadowing, as confirmed by photometric studies of other asteroids. Then, the photometric properties of the artificial impact crater area revealed a slight phase function steepening and narrowing after the impact: this could indicate that the exposed surface has a larger roughness and more porous particles.
A pilot study to quantify and describe personal social networks in patients with glioblastoma
Authors: Rhee John Y , Mastrangelo Carissa , Miller Paul J , Youssef Gilbert , Tentor Zachary , Rothfeld-Wehrwein Zachary R , Dhongade Vrushali A , Nakhate Vihang , Batchelor Tracy , Dhand Amar 
Published: January 2025

Abstract

Background
Patients with glioblastoma experience high physical and psychosocial symptom burden. Poor social relationships have been shown to increase the risk of neurologic illnesses and decline, and conversely, strong personal social networks (PSN) have been shown to reduce the risk of mortality and improve quality of life. The aim of this pilot study is to determine the feasibility of measuring PSN in glioblastoma patients.

Methods
We recruited 25 adult glioblastoma patients between the initial diagnosis and the first cycle of adjuvant chemotherapy from March to September 2023 in the outpatient neuro-oncology clinic and adapted PERSNET, a quantitative PSN assessment tool, to this population. We collected demographics, tumor measures, treatment courses, and the European Organization for Research and Treatment of Cancer QOL for Patients with Brain Tumors (EORTC QLQ-BN20) and conducted qualitative interviews.

Results
The average age was 64.5 years old, 56% were female, and 84% had a Karnofsky Performance Status of 70 or higher. Patients had large network sizes (total size of patient’s PSN; mean = 8.8). Participants stressed the importance of social support and how different people filled different roles in their oncology care. Behavioral and/or cognitive changes resulted in delayed presentation, and children, especially daughters, were important in advocating for presentation to the hospital.

Conclusion
This is the first proof-of-concept study showing that PSN can be measured in patients with glioblastoma. Qualitative data showed that patients felt social support was very important, and different people in their networks addressed different domains of care: physical, emotional, and logistical.