bluuebunny/crossref_metadata_2025_split huggingface dataset:
A georeferenced database of the edaphic biota currently available for Argentina
Authors: Sanabria María Cynthia Valeria , Velazco Víctor , Tolosa Gabriel , Falco Liliana , Coviella Carlos 
Published: September 2023

Soils have been studied and classified in terms of their physical and chemical characteristics, while the knowledge about biodiversity and the ecosystem processes that they support is lagging behind. Furthermore, the advance in scientific knowledge contributed by different researchers is dispersed and it is necessary to collect it to bring the big picture into focus. Today it is possible to have the findings and data collected by different researchers, compile them and, based on technological advances, have tools that allow the information to be analyzed in its entirety. The main objective of this work is to compile and systematize all the bibliographic information available on the main organisms that make up biodiversity in the soil: Acari, Collembola and Crassiclitellata in Argentina. A second objective is to link the composition and structure of the soil community with processes and flows in the ecosystem, and to estimate them at different scales and in soils with different anthropic impact. The database presented here gathers presence information on the mentioned taxa, their geographical location for the entire country, while preserving the identity and authorship of each scientific work retrieved. The taxonomic range of the organisms of the edaphic biota collected in this database ranges from class to subspecies, and are registered based on the taxonomic level reported by the original author in their research. The publications were obtained from Google Scholar, Scopus and JSTOR. In addition, records were added from INEDES theses, library searches, information requested from authors cited in other articles and unpublished works. In total, information was collected from 224 scientific publications, as well as personal information requested directly to some authors. The total number of registered individuals so far is 4838 of which 3049 specimens correspond to Acari, 944 to Classiclitellata and 845 belong to Collembola.
This work is the first to gather, in a single publication, the entire dataset for all the Acari, Collembola, and Clitellata recorded for Argentina.
Typologie des stratégies de divulgation de résultats non-GAAP en France : une approche multifactorielle
Authors: Davrinche Grégoire 
Published: September 2023

Les résultats non-GAAP (résultats non conformes aux normes comptables) sont aujourd’hui une composante majeure de la communication volontaire des entreprises. Malgré une littérature importante sur le sujet, très peu de travaux permettent de documenter de façon exhaustive la manière dont sont communiqués ces indicateurs. L’objectif de cet article est donc de dresser une typologie des stratégies de divulgation de résultats non-GAAP adoptées en France. Une Analyse de Correspondances Multiples (ACM) conduite sur un échantillon de 512 firmes-années entre 2011 et 2017 nous a permis de mettre en évidence quatre grands types de stratégies : (i) les stratégies « agressives », (ii) les stratégies « proactives », (iii) les stratégies « conventionnelles » et (iv) les stratégies « normalisées ».
Santé sexuelle, sexualité et cancer : oxymore, aporie, réalité ?
Authors: Arnault Yolande 
Published: September 2023

Comment peut-on penser ce qui de prime abord peut paraître en parfaite contradiction et qui est proposé ici à notre réflexion : « Santé sexuelle, sexualité et cancer » ? Du cancer on en a parlé, on en parle et on en parlera encore… Ce cancer qui vient brutaliser, parfois anéantir, au mieux pour un temps ou au pire de façon durable, la vie des malades. Comment peut-on envisager la santé sexuelle et la sexualité pendant et après l’épreuve imposée par la maladie cancéreuse ? Est-ce une question qui ne peut mener qu’à une impasse ?
La rhétorique du hoquet à texte brisé : enjeux analytiques, poétiques et sonores dans les motets du xiv e siècle
Authors: Roger Kévin 
Published: September 2023

Les motets isorythmiques du xiv e siècle disposent de nombreux procédés impliquant le plus souvent une maîtrise du syllabisme et une cohérence des discours textuel et musical. Cependant, le cas de plusieurs hoquets à texte brisé incite à interroger la place des paroles dans le processus de composition. Face à l’apparent désintérêt pour les vers, qui émane de cette pratique, la littérature musicologique a généralement considéré ces hoquets comme fautifs à l’égard de la rhétorique. Mais la révision de commentaires de la fin du Moyen Âge ainsi que l’analyse de certains motets démontrent que leur réalisation relève de principes poétiques et textuels sous-jacents. En effet, la division supposément arbitraire des mots dissimule diverses stratégies de composition dont l’objectif est d’assurer une diction et une compréhension convenable des paroles.
Le rôle de la Faculté des Sciences d’Alger dans le développement des sciences appliquées en contexte colonial ( xix e - xx e siècle)
Authors: Bettahar Yamina 
Published: September 2023

Cette contribution se fonde sur l’analyse de la Faculté des Sciences d’Alger, créée en 1909 dans le cadre de l’institutionnalisation et le développement d’une université coloniale destinée quasi exclusivement aux Européens. Elle est l’émanation d’un embryon d’enseignement supérieur colonial mis en place dès le milieu du xix e siècle pour servir les impératifs et les besoins de « mise en valeur » de la colonie. Résolument orientée dès sa création vers les sciences appliquées, elle se professionnalise progressivement et prend rang parmi les institutions académiques françaises dès le début du xx e siècle. Une telle étude permet de saisir certaines étapes dans la construction et la mise en place d’un enseignement supérieur colonial compris selon les enjeux du contexte spécifique de sa création et de son développement. Cette étude offre également l’opportunité de faire la distinction entre l’institutionnalisation, l’adaptation, la professionnalisation des disciplines et des enseignants, voire l’autonomie relative des activités scientifiques vis-à-vis des acteurs politiques, dans le cadre d’une socio-histoire d’un territoire particulier.
Du discrédit des partis à la discrétion partisane
Authors: Sainsaulieu Ivan , Sawicki Frédéric , Talpin Julien 
Published: September 2023

La littérature sur les partis politiques est dominée par la question de leur perte de légitimité et d’ancrage social. Sans nier le discrédit dont ils sont l’objet et qui se traduit notamment par l’émergence de nouvelles formes d’entreprises électorales, cet article introductif plaide pour un glissement de la question du discrédit vers celle de la discrétion, glissement qui permet à la fois d’éviter de considérer le discrédit comme un phénomène nouveau et univoque et de concevoir les partis comme passifs à son égard. La question de la discrétion partisane permet d’abord d’interroger la façon dont les responsables et les militants de ces nouvelles entreprises politiques mais aussi des partis installés s’arrangent avec les formes contemporaines de discrédit assez radical qu’ils co-produisent ou qu’ils subissent. Elle permet aussi, en s’interrogeant sur les formes prises par la discrétion partisane hier et aujourd’hui, de souligner que les stratégies discrètes caractérisent également une grande variété de situations (risques de répression, désarmement de la critique adverse, affichages modulés en fonction de compromis sociaux…) et concernent souvent des territoires où la domination des partis est bien établie. Recontextualisée, la discrétion n’apparaît pas seulement comme la forme standard de la politique « professionnelle » contemporaine, mais comme un ensemble de tactiques et de stratégies qui résultent de la tension qui traverse tout parti, pris entre son ou ses dedans et ses dehors.
« La disparition » : les usages de la discrétion dans l’agir de Génération identitaire
Authors: Jacquet-Vaillant Marion 
Published: September 2023

Comment, dans le répertoire tactique identitaire, scandalisation et discrétion se combinent-elles ? Et surtout, pourquoi ? En mobilisant des entretiens avec des militants, des observations et une analyse des archives du mouvement et de revues de presse, cet article montre que, si Génération identitaire est connue pour sa stratégie de scandalisation, celle-ci masque effectivement une stratégie discrète. Elle repose sur un morcellement organisationnel qui permet à l’organisation de disparaître dans certaines situations. Cette stratégie apparaît comme un moyen de gérer le stigmate extrême droitier, facilitant les recrutements et protégeant le mouvement. À partir de cette étude de cas, cet article contribue à une compréhension de ce qu’est la discrétion (en) politique, tout en éclairant l’hybridation des répertoires d’action des mouvements sociaux contemporains.
Le sport, un instrument de la guerre politique de Vladimir Poutine contre l’Occident
Authors: Aubin Lukas 
Published: September 2023

Pour Vladimir Poutine, le sport est un instrument de sa « guerre politique » contre l’Occident. En effet, depuis l’an 2000, le sport participe de la « puissance de l’imaginaire » russe, conçue par le Kremlin pour illustrer son retour au premier plan du concert des nations et influencer la marche du monde. Depuis le 24 février 2022, en raison des sanctions, le président russe est toutefois partiellement privé de cet instrument de puissance de premier plan, héritier des représentations du modèle sportif de l’URSS, de la guerre froide du sport et des glorieuses victoires des athlètes soviétiques. Cependant, le sport est polymorphe et ses usages multiples. Dès lors, comment le régime utilise-t-il le sport en temps de guerre ? Quelles sont ses racines militaires ? Pourquoi le sport power est-il une arme de la guerre politique de Vladimir Poutine contre l’Occident ?
Mitochondrial transplantation confers protection against the effects of ischemic stroke by repressing microglial pyroptosis and promoting neurogenesis
Authors: Sun Li , Zhao Zhaoyan , Guo Jing , Qin Yuan , Yu Qian , Shi Xiaolong , Guo Fei , Zhang Haiqin , Sun Xude , Gao Changjun , Yang Qian 
Published: September 2023

Abstract

JOURNAL/nrgr/04.03/01300535-202406000-00037/inline-graphic1/v/2023-10-30T152229Z/r/image-tiff

Transferring healthy and functional mitochondria to the lateral ventricles confers neuroprotection in a rat model of ischemia-reperfusion injury. Autologous mitochondrial transplantation is also beneficial in pediatric patients with cardiac ischemia-reperfusion injury. Thus, transplantation of functional exogenous mitochondria may be a promising therapeutic approach for ischemic disease. To explore the neuroprotective effect of mitochondria transplantation and determine the underlying mechanism in ischemic stroke, in this study we established a photo-thrombosis-induced mouse model of focal ischemia and administered freshly isolated mitochondria via the tail vein or to the injury site (in situ). Animal behavior tests, immunofluorescence staining, 2,3,5-triphenyltetrazolium chloride (TTC) staining, mRNA-seq, and western blotting were used to assess mouse anxiety and memory, cortical infarct area, pyroptosis, and neurogenesis, respectively. Using bioinformatics analysis, western blotting, co-immunoprecipitation, and mass spectroscopy, we identified S100 calcium binding protein A9 (S100A9) as a potential regulator of mitochondrial function and determined its possible interacting proteins. Interactions between exogenous and endogenous mitochondria, as well as the effect of exogenous mitochondria on recipient microglia, were assessed in vitro. Our data showed that: (1) mitochondrial transplantation markedly reduced mortality and improved emotional and cognitive function, as well as reducing infarct area, inhibiting pyroptosis, and promoting cortical neurogenesis; (2) microglial expression of S100A9 was markedly increased by ischemic injury and regulated mitochondrial function; (3) in vitro, exogenous mitochondria enhanced mitochondrial function, reduced redox stress, and regulated microglial polarization and pyroptosis by fusing with endogenous mitochondria; and (4) S100A9 promoted internalization of exogenous mitochondria by the microglia, thereby amplifying their pro-proliferation and anti-inflammatory effects. Taken together, our findings show that mitochondrial transplantation protects against the deleterious effects of ischemic stroke by suppressing pyroptosis and promoting neurogenesis, and that S100A9 plays a vital role in promoting internalization of exogenous mitochondria.
Neuroprotective effects of chaperone-mediated autophagy in neurodegenerative diseases
Authors: Jia Qi , Li Jin , Guo Xiaofeng , Li Yi , Wu You , Peng Yuliang , Fang Zongping , Zhang Xijing 
Published: September 2023

AbstractChaperone-mediated autophagy is one of three types of autophagy and is characterized by the selective degradation of proteins. Chaperone-mediated autophagy contributes to energy balance and helps maintain cellular homeostasis, while providing nutrients and support for cell survival. Chaperone-mediated autophagy activity can be detected in almost all cells, including neurons. Owing to the extreme sensitivity of neurons to their environmental changes, maintaining neuronal homeostasis is critical for neuronal growth and survival. Chaperone-mediated autophagy dysfunction is closely related to central nervous system diseases. It has been shown that neuronal damage and cell death are accompanied by chaperone-mediated autophagy dysfunction. Under certain conditions, regulation of chaperone-mediated autophagy activity attenuates neurotoxicity. In this paper, we review the changes in chaperone-mediated autophagy in neurodegenerative diseases, brain injury, glioma, and autoimmune diseases. We also summarize the most recent research progress on chaperone-mediated autophagy regulation and discuss the potential of chaperone-mediated autophagy as a therapeutic target for central nervous system diseases.
Dysregulation of RNA modification systems in clinical populations with neurocognitive disorders
Authors: Knight Helen M. , Demirbugen Öz Merve , PerezGrovas-Saltijeral Adriana 
Published: September 2023

Abstract
The study of modified RNA known as epitranscriptomics has become increasingly relevant in our understanding of disease-modifying mechanisms. Methylation of N6 adenosine (m6A) and C5 cytosine (m5C) bases occur on mRNAs, tRNA, mt-tRNA, and rRNA species as well as non-coding RNAs. With emerging knowledge of RNA binding proteins that act as writer, reader, and eraser effector proteins, comes a new understanding of physiological processes controlled by these systems. Such processes when spatiotemporally disrupted within cellular nanodomains in highly specialized tissues such as the brain, give rise to different forms of disease. In this review, we discuss accumulating evidence that changes in the m6A and m5C methylation systems contribute to neurocognitive disorders. Early studies first identified mutations within FMR1 to cause intellectual disability Fragile X syndromes several years before FMR1 was identified as an m6A RNA reader protein. Subsequently, familial mutations within the m6A writer gene METTL5, m5C writer genes NSUN2, NSUN3, NSUN5, and NSUN6, as well as THOC2 and THOC6 that form a protein complex with the m5C reader protein ALYREF, were recognized to cause intellectual development disorders. Similarly, differences in expression of the m5C writer and reader effector proteins, NSUN6, NSUN7, and ALYREF in brain tissue are indicated in individuals with Alzheimer’s disease, individuals with a high neuropathological load or have suffered traumatic brain injury. Likewise, an abundance of m6A reader and anti-reader proteins are reported to change across brain regions in Lewy bodies diseases, Alzheimer’s disease, and individuals with high cognitive reserve. m6A-modified RNAs are also reported significantly more abundant in dementia with Lewy bodies brain tissue but significantly reduced in Parkinson’s disease tissue, whilst modified RNAs are misplaced within diseased cells, particularly where synapses are located. In parahippocampal brain tissue, m6A modification is enriched in transcripts associated with psychiatric disorders including conditions with clear cognitive deficits. These findings indicate a diverse set of molecular mechanisms are influenced by RNA methylation systems that can cause neuronal and synaptic dysfunction underlying neurocognitive disorders. Targeting these RNA modification systems brings new prospects for neural regenerative therapies.
Immune modulation by probiotics in deterring carcinogenesis with an emphasis on oral cancer: A narrative review
Authors: Vasanthi V , Sanjeev Kavitha , Rajkumar Krishnan , Divya Bose , Rameshkumar Annasamy , Swarup Shanti , Ramadoss Ramya 
Published: September 2023

ABSTRACT
Probiotics modulate immune responses, enhance anti-tumoral immune surveillance, promote apoptosis of cancer cells, suppress tumor progression by their cytotoxic activity, and target the epigenetic changes in the cancer cell population. Evidence from the literature suggests that the role of probiotics in oral carcinogenesis is limited as compared to that in colon and gastric cancer. The present review aims to describe the immune modulation by probiotics in deterring carcinogenesis with an emphasis on oral cancer. We searched for relevant articles (in vitro and animal studies) published between January 2011 and December 2022 in PubMed, Scopus, and Google Scholar, both by electronic and manual means with the medical subject headings (MeSH) terms: “probiotics,” “carcinogenesis,” “immune modulation,” and “oral cancer.” The identified studies were analyzed by two independent reviewers according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Eight articles met the requirements and were included. The data suggested that probiotics had immunomodulatory and anti-tumorigenic effects. Clinical studies are required to encourage the assessment of probiotics to inhibit tumor cell proliferation, prevent metastasis, and support anti-cancer therapy.
Novel laparo-endoscopic hybrid technique of management of a rare case of duodeno-duodenal intussusception
Authors: Shenoy K. Ganesh , Gadiyaram Srikanth , Ramesh B. S. 
Published: September 2023

Abstract
We herein report a rare case of duodeno-duodenal intussusception (IS) presenting with obstruction caused by tubulovillous adenoma in an adult with malrotation that was managed by a novel laparoendoscopic hybrid technique. This was done by passing transjejunal nasogastric tube (NG) through one of the ports and manoeuvring it towards the IS. Two hundred and fifty millilitre of saline was flushed by aseptosyringe with pressure connected to the NG. This hydrostatic reduction technique resulted in distension of the jejunal and duodenal loop achieving reduction of IS. Intraoperative endoscopy was performed to exactly localise the mass lesion. The duodenum was kocherised and was delivered through a 4-cm transverse incision. Anterior duodenotomy was performed; the mass was excised; and duodenotomy was closed transversely. An extensive literature search did not show any case report of duodenoduodenal IS being managed by this technique. The combination of novel retrograde decompression and intraoperative endoscopy helped us to manage this rare case by this novel technique.
Outcomes of laparoscopic single-incision caecal pole resection for low-grade appendiceal mucinous neoplasm
Authors: Kwak Han Deok 
Published: September 2023

Abstract

Introduction:
Low-grade appendiceal mucinous neoplasm (LAMN) is a rare disease, and its clinical course varies from an incidental finding without symptoms to pseudomyxoma peritonei. Furthermore, there are few established treatment guidelines. This study was designed to confirm the outcomes in patients diagnosed with LAMN who underwent single-incision laparoscopic caecal pole resection.

Patients and Methods:
This study was conducted on pathologically confirmed LAMNs from patients who underwent surgery at a single centre, a tertiary institution, from July 2016 to August 2022. Patients diagnosed with LAMN as a result of biopsy were included. All surgeries were performed with single-incision laparoscopic caecal pole resection by a single surgeon.

Results:
A total of 70 patients were included. The median age was 65.5 years and 36 (51.4%) patients were female. The baseline carcinoembryonic antigen (CEA) was 8.08 ng/mL (0.76–148.11). The mean maximum diameter was 29.4 mm (7–70) and calcification was seen in 22 cases on pre-operative computed tomography (CT). As a result of histological examination, all patients were marginally negative. The larger the tumour size, the higher the CEA was (P = 0.011), and it was often accompanied by calcification (P = 0.021). In addition, tumour size and CEA showed a positive partial correlation with each other (r = 0.318, P = 0.018). The overall median follow-up period was 22.7 months (2–60). One case had suspected of recurrence on CT scan performed at 33 months following the surgery, but there were no related symptoms.

Conclusion:
Single-port laparoscopic caecal pole resection without margin involvement in LAMN was safe and feasible, and showed a favourable long-term outcome.
The efficacy and feasibility of neoadjuvant immunotherapy plus chemotherapy followed by McKeown minimally invasive oesophagectomy for locally advanced oesophageal squamous cell carcinoma
Authors: Luo Rao-Jun , Li Zhi-Jun , He Zheng-Fu , Yan Pei-Jian , Wang Yun-Zheng , Xu Shao-Hua , Zhu Zi-Yi 
Published: September 2023

Abstract

Introduction:
In immunotherapy, antibodies are activated to block immune checkpoints, resist tumour immunosuppression, shrink tumours and prevent a recurrence. As the science behind tumour immunotherapy continuously develops and improves, neoadjuvant immunotherapy bears more prominent advantages: antigen exposure not only enhances the degree of tumour-specific T-cell response but also prolongs the duration of actions. In this study, we evaluated the efficacy and safety of McKeown minimally invasive oesophagectomy (McKeown MIO) following neoadjuvant immunotherapy combined with chemotherapy (NICT) in patients with locally advanced oesophageal cancer (OC).

Patients and Methods:
In this retrospective study, 94 patients underwent either NICT or neoadjuvant chemotherapy (NCT) followed by MIO at our institution from January 2020 to October 2022. We assessed the therapy-related adverse events and perioperative outcomes and compared them between the two groups.

Results:
After completing at least two cycles of neoadjuvant therapy, all patients underwent McKeown MIO with negative margins within 4–7 weeks. Demographic data of the two cohorts were similar. Regarding perioperative characteristics, the median intraoperative blood loss was 50 ml in the NICT group, lower than that of the NCT group (100 ml, P < 0.05). In addition, the NICT group had significantly more harvested lymph nodes than the NCT group (P < 0.05). No significant differences were found in post-operative complications. The rate of objective response rate in the NICT group was higher than that in the NCT group (88.3% vs. 58.8%). Regarding tumour regression, the number of patients with TRG Grades 1–3 in the NICT group was more than that in the NCT. Adverse events experienced by the two groups included anaemia and elevated transaminase. We found no difference in the adverse events between the two groups.

Conclusions:
This study showed the efficacy and feasibility of NICT followed by McKeown MIO in treating locally advanced OC.