bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using meta‐research to foster diverse, equitable, and inclusive collaborative research networks
Authors: Stevens Elizabeth R. , Brody Abraham A. , Epps Fayron , Sloan Danetta H. , Sherman Scott E. 
Published: December 2022

AbstractFostering diverse, equitable, and inclusive collaborative research networks is important for advancing the field of aging research. Despite sizeable investment in research consortia and career development programs, there has been only moderate progress toward diversifying the research workforce studying aging. Without critically examining what works and what does not, continuing to place more resources into these same strategies may not result in a substantial improvement in diversity or the creation of collaborative networks. Using meta‐research to rigorously evaluate potential strategies to promote diversity and collaboration may yield important insights that can be used to improve upon current efforts. For this reason, we sought to describe meta‐research and highlight how its principles can be used to achieve the aging research community's collaboration and diversity goals.
Three‐point sectional‐cast digital method for transferring the interocclusal relationship for full‐mouth rehabilitation of worn dentition
Authors: Liu Xiaoqiang , Zhou Ti , Gao Hanqi , Zhou Jianfeng , Li Deli , Tan Jianguo 
Published: December 2022

AbstractFor full‐mouth rehabilitation of worn dentition, “diagnostic” interim restorations are required to reestablish the interocclusal relationship. It is important but challenging to transfer the interocclusal relationship and to map the basic form and contour of interim restorations to the final restorations. Alignment of interim restorations and working casts is difficult when using digital workflows because of a lack of consistent hard tissue reference points. The digital workflow presented in this study used a “3‐point sectional‐cast digital cross‐mounting method” to transfer the interocclusal relationship during full‐mouth rehabilitation. An intermediate cast was made with three interim restorations: one on an incisor and two on molars. The interocclusal relationship and occlusal morphologies of the diagnostic interim prostheses were transferred and aligned to working casts using the 3‐point sectional casts.
Phylogenomics, divergence time estimation, and adaptive evolution in the Polygonoideae (Polygonaceae)
Authors: Cao Dong‐Ling , Zhang Xue‐Jie , Qu Xiao‐Jian , Fan Shou‐Jin 
Published: December 2022

AbstractPrevious phylogenetic analyses indicated that Polygonoideae, the largest subfamily in the Polygonaceae, is monophyletic. Phylogenetic relationships within the Polygonoideae have been substantially controversial. We collected 160 samples representing all currently recognized tribes for a more comprehensive phylogenetic analysis of the subfamily. Here, we reconstructed phylogenetic relationships of the Polygonoideae, inferred ancestral character states, and estimated the divergence time with a dense taxon sampling. This study corroborated and expanded previous results regarding the phylogenetic relationships of the Polygonoideae clade, and resolved the phylogenetic status of some controversial taxa by integrating molecular and morphological evidence. Phylogenetic analyses based on the complete plastomes suggested strong support for six primary clades that correspond to the most recent circumscription of tribes: Polygoneae, Rumiceae, Calligoneae, Pteroxygoneae, Fagopyreae, and Persicarieae. In addition, we provided further morphological data and assessed characters that supported different clades. The 3‐colpate pollen, 5‐parted perianth, and 3 styles were inferred to be the ancestral states of Polygonoideae. Divergence time estimation revealed that Polygonoideae originated around the late Cretaceous, and diversification was concentrated in the Eocene and Miocene. Time estimation indicated that the rapid uplift of the Tibetan Plateau and the intensification of the Asian monsoons might be potential driving forces for the diversification of Polygonoideae. Overall, this study advances our understanding of the phylogeny and diversification of the Polygonoideae and highlights the adaptive evolution of the taxa.
Metabolic dysfunction associated fatty liver disease identifies subjects with cardiovascular risk better than non‐alcoholic fatty liver disease
Authors: Chun Ho Soo , Lee Minjong , Lee Jae Seung , Lee Hye Won , Kim Beom Kyung , Park Jun Yong , Kim Do Young , Ahn Sang Hoon , Lee Yong‐Ho , Kim Ji‐Hye , Kim Seung Up 
Published: December 2022

AbstractBackground and AimsCardiovascular disease (CVD) is the main cause of mortality in subjects with non‐alcoholic fatty liver disease (NAFLD). We investigated the association between CVD risk and metabolic dysfunction‐associated fatty liver disease (MAFLD) or NAFLD and the influence of significant liver fibrosis on the CVD risk.MethodsSubjects who underwent a comprehensive medical check‐up were recruited (2014–2019). Significant liver fibrosis was defined using NAFLD fibrosis score, fibrosis‐4 index, aspartate aminotransferase to platelet ratio index, or FibroScan‐aspartate aminotransferase score. High probability of atherosclerotic CVD (ASCVD) was defined as ASCVD risk score > 10%.ResultsOf the study population (n = 78 762), 27 047 (34.3%) and 24 036 (30.5%) subjects had MAFLD and NAFLD respectively. A total of 1084 (4.0%) or 921 (3.8%) subjects had previous CVD history in MAFLD or NAFLD subgroup respectively. The previous CVD history and high probability of ASCVD were significantly higher in MAFLD or NAFLD subgroup with significant liver fibrosis than in the other groups (all p < .001). In multivariable analysis, MAFLD was independently associated with previous CVD history after adjusting for confounders (adjusted odds ratio [aOR] = 1.10, p = .038), whereas NAFLD was not (all p > .05). MAFLD (aOR = 1.40) or NAFLD (aOR = 1.22) was independently associated with high probability of ASCVD after full adjustment respectively (all p < .001). Significant liver fibrosis was independently associated with previous CVD history and high probability of ASCVD after adjustment in MAFLD or NAFLD subgroup respectively (all p < .05).ConclusionMAFLD might better identify subjects with CVD risk than NAFLD. Fibrosis assessment might be helpful for detailed prognostication in subjects with MAFLD.
Assessment of the current trophic state and water quality of Lake Naivasha, Kenya using multivariate techniques
Authors: Yongo Edwine , Agembe Simon W. , Manyala Julius O. , Mutethya Eunice 
Published: December 2022

AbstractLake Naivasha is a tropical freshwater body in Kenya, providing a source of livelihoods to the surrounding communities. The lake ecosystem, however, has become degraded over time because of increasing pollutant loads from multiple sources, including human settlements and agricultural and surface runoff in its basin. Thus, it is vital to study the lake's water quality to determine its current status to inform appropriate management measures. Accordingly, the present study analysed water quality parameters and the trophic state of Lake Naivasha on the basis of water samples collected at eight sampling sites during the dry and wet seasons from December 2019 to May 2020. The physico‐chemical parameters were measured in situ, while nutrients were analysed in the laboratory. The results indicated high turbidity, total nitrogen (TN), ammonium‐nitrogen (NH4+‐N), nitrate‐N (NO3‐N) and total phosphorus (TP) levels during the wet season, and at the Malewa and Karati River mouths, while pH, electrical conductivity (EC) and chlorophyll‐a values were relatively high during the dry season. The water temperature and dissolved oxygen (DO) concentration, however, did not vary between sampling sites or seasons. Cluster analysis (CA) classified the sites into three clusters based on water quality spatial and seasonal variations. Cluster 1 was comprised of the isolated region (Crescent), while clusters 2 and 3 mainly comprised sites sampled during wet and dry seasons, respectively. Similarly, principal component analysis (PCA) revealed spatial and seasonal physico‐chemical variations, indicating nutrient parameters (TN, TP, NO3‐N and NH4+‐N), pH, Secchi depth and turbidity are the major variables influencing water quality variations. Furthermore, factor analysis (FA) identified nutrients, sediment and organic sources as the main lake pollution sources. The trophic state index (TSI = 60–72) indicated the lake varied from a eutrophic to hypertrophic state during the study period. The lake was found to be more eutrophic than reported in previous studies, indicating a progressive deterioration of its water quality. The overall results demonstrated some of the sampling sites in the lake are heavily contaminated with pollutants from various sources, attributable primarily to land use patterns and anthropogenic activities. The results of the present study are useful to inform decisions regarding management of the lake water quality.
The effect of training on coronary artery bypass graft surgery patients
Authors: Olgun Sule , Ozsaker Esma 
Published: December 2022

AbstractBackgroundIn the pre‐operative process, patients who will undergo cardiovascular surgery and their families require planned education and education materials. Education given to patients plays a key role in reducing anxiety, overcoming stress, and accelerating discharge.AimsThis study was conducted to determine the effect of an education booklet in addition to training by nurses on efficacy expectation, pain and anxiety levels in coronary artery bypass grafting (CABG) surgery patients.Study DesignThis quasi‐experimental study was conducted in the cardiovascular surgery service of a university hospital in Izmir, Turkey, between June and October 2018 and involved 60 patients. The patients were divided into two groups: control (n = 30) and intervention (n = 30). The intervention group was patients educated before surgery by using the booklet, but the control group only received routine care by nurses. The data were collected using the Mini‐Mental Test, Patient Information Form, Visual Analogue Pain Scale, Spielberger State‐Trait Anxiety Scale, Barnason Efficacy Expectation Scale, and Education Evaluation Form.ResultsAfter the intervention at discharge, there was a significant difference between the mean scores of anxiety, pain, and efficacy expectation among the intervention group which received booklet education with the control group which received routine care (p <  .05).ConclusionThe booklet education given to patients before CABG surgery was found to have potential effects on patients' post‐operative pain levels, the efficacy expectation, and satisfaction.Relevance to Clinical PracticeIn the pre‐operative process, the use of booklet education in addition to routine care increases the level of efficacy expectation and decreases pain and anxiety in CABG surgery patients. Therefore, nurses can use booklet education to improve self‐efficacy and reduce pain and anxiety in patients who have CABG surgery.
Inappropriate ventricular fibrillation annotation and defibrillator discharge despite the same tachycardia cycle length in ventricular tachycardia‐1 zone in an Abbott defibrillator – What is the mechanism?
Authors: Bera Debabrata , Mani Siddhartha , Sen Ranabrata , Majumder Suchit , Halder Antareep , Ray Adrita 
Published: December 2022

AbstractNewer devices incorporate advanced algorithms to have more accurate delivery of implantable cardioverter‐defibrillator (ICD) therapy. Newer models of Abbott Implantable cardioverter‐defibrillators like Gallant and Entrant have a new ventricular fibrillation (VF) therapy assurance algorithm. This algorithm has a proven role in avoiding under‐detection of VF where some of the smaller electrograms are under‐sensed. We report a case of ventricular fibrillation therapy assurance (VFTA) algorithm malfunction in a 48‐year‐old lady having single chamber Entrant Implantable cardioverter‐defibrillator, where the patient received inappropriate therapies. The VFTA algorithm eventually had to be turned off.
Experiences and Perspectives of College Students With Disabilities Toward Integrated Physical Education in South Korea
Authors: Lee Seo Hee , Hodge Samuel R. 
Published: December 2022

The purpose of the study was to analyze South Korean college students with disabilities’ recollections about their experiences in segregated (self-contained) special education classes and integrated physical education classes during elementary, middle, and/or high school in South Korea. The research design was retrospective multiple-case study. The participants were five South Korean college students matriculating at a university in South Korea. The primary data sources were semistructured interviews and researcher’s journal entries. The data were analyzed using thematic analysis and exposed four interrelated themes, which were (a) isolated, (b) felt not supported, (c) segregated from peers, and (d) felt relieved and safe. Overall, the findings exposed challenges the participants all had experienced in integrated physical education classes, including feeling isolated and excluded from meaningful participation in class activities. In contrast, they reflected on their experiences in the segregated (self-contained) special education classes with a sense of belonging and acceptance.
Career Transitions: Decision-Making Dynamics Regarding Physical Education Teacher Education Doctoral Program Applications and Entry
Authors: Patton Kevin , Parker Melissa 
Published: December 2022

Purpose: This study’s purpose was to explore professional career paths into physical education teacher education. Methods: Participants included 27 physical education teacher educators with an average of 20.2 years of experience selected from among attendees at international conferences, using a combination of convenience and purposive sampling. Data sources included semistructured interviews, living graphs, and participant vitae. Results: Findings describe intrinsic and extrinsic motivating factors to pursue a professional role change and the selection of a doctoral program including: (a) prompted by others, (b) self-initiated, and (c) forced choice. After deciding to pursue a doctoral degree, program choice was predicated by disciplinary and institutional, as well as idiosyncratic and personal considerations. Conclusions: Understanding how and why participants repositioned themselves from their current roles into doctoral education has important implications for further research and practice to enhance the quality of doctoral education.
Hybrid‐Mobile Stroke Unit: Opening the Indication Spectrum for Stroke Mimics and Beyond
Authors: Fassbender Klaus , Phillips Daniel J. , Grunwald Iris Q. , Schottek Andrea , Alam Sajid , Perera Saman , Chakrabarti Annie , Moon Robert , Lesmeister Martin , Wagner Viola , Wheddon Damon , Dommett David , Wells Brittany , Middleton Rheanne , Willis Robert , Bachhuber Monika , Merzou Fatma , Wagenpfeil Stefan , Thottath Jineesh , Bertsch Thomas , Walter Silke ,   for the Hybrid‐MSU Working Group
Published: December 2022

Background
Despite proven benefits, the use of single‐purpose mobile stroke units (MSUs) has raised concerns about their effective and cost‐efficient integration into clinical practice, especially when considered for operation in nonurban areas. The MSU concept may benefit from opening the indication spectrum to include frequent stroke mimics and additional emergencies.

Methods
The current observational study evaluated benefits for the treatment and triage decision‐making of use of an MSU with extended capabilities (Hybrid‐MSU), also including radiography, ultrasonography, extended point‐of‐care laboratory, ECG, electroencephalography, and advanced medications. Apart from patients with a dispatch code for “stroke”, the ambulance was also dispatched to those with codes for “seizures”, “falls with head trauma”, “headache”, “unconsciousness”, “infection and pandemic”, “chest pain”, and “breathing problems”.

Results
For 250 patients treated by the Hybrid‐MSU, but not for 250 conventionally treated patients, the prehospital diagnostic workup allowed, apart from treatment with stroke thrombolytics (n=15), prehospital administration of specific anticonvulsants (n=15), antibiotics (n=5), early secondary stroke prophylaxis with aspirin (n=49), and the Sepsis Six bundle (n=2). Prehospital diagnosis avoided 215 (86.0%) admissions to the emergency department, either by management at home (n=116, 46.4%) or by directly transferring patients to the required specialized wards (n=99, 39.6%).

Conclusion
The current study demonstrates the feasibility of the use of a Hybrid‐MSU and indicates its potential benefits for prehospital treatment and triage decision‐making. Opening the indication spectrum, together with an act‐alone ability, could be a key in the future integration of MSUs into routine health care.
Academic Publishing and the Indian Book Trade
Authors: Chesher Christoph 
Published: December 2022

Abstract
Christoph Chesher joined publishing in 1984 as a sales rep at Blackwell Science (BSP) and built up a sales team ground up in the UK and abroad including India – he had an instant connection with the country and its vibrant books market. In 1993 he joined OUP and came to Routledge/T&F in 1997, where he took the key decision to set up an India liaison office, which has since gone from strength to strength, expanding to a full-scale publisher. Large wholesalers continue to play a big part in servicing the extensive but fragmented Indian market, and levels of discounts, concerns around arbitrage, levels of copyright awareness and an overreliance on print by the key trade partners remain key challenges for publishers in India.
Interventional Strategies in the Ukrainian Dubbing of "The Simpsons Movie" (2007)
Authors: Weston Olena 
Published: December 2022

This article analyses the interventional translation strategies employed in the Ukrainian dubbing of The Simpsons Movie (2007). Based on a parallel corpus of the English original and the Ukrainian dubbing, this paper argues that film translation frequently requires lexical adjustments by the translator in order to maintain the original context or to establish the desired emotional connection with the audience. The interventional strategies chosen for this paper and applied to detected Ukrainian fragments are generalisation, substitution and omission, which are elements of domestication strategies; and specification, which is an element of foreignization strategies. In the process of analysing the parallel corpus for The Simpsons Movie, an additional type of interventional strategy was detected and added as a fifth category: lexical domestication. This strategy relates to elements that have been deliberately created with the aim of introducing foreign replicas closer to the target language.
Greater angiogenic and immunoregulatory potency of bFGF and 5-aza-2ʹ-deoxycytidine pre-treated menstrual blood stem cells in compare to bone marrow stem cells in rat model of myocardial infarction
Authors: Manshori Mahmood , Kazemnejad Somaieh , Naderi Nasim , Darzi Maryam , Aboutaleb Nahid , Golshahi Hannaneh 
Published: December 2022

Abstract
Background
This study is designed to compare the menstrual blood stem cells (MenSCs) and bone marrow stem cells (BMSCs)-secreted factors with or without pre-treatment regimen using basic fibroblast growth factor (bFGF) and 5-aza-2ʹ-deoxycytidine (5-aza) and also regenerative capacity of pre-treated MenSCs and/or BMSCs in a rat model of myocardial infarction (MI).

Methods
BMSCs and MenSCs were pre-treated with bFGF and 5-aza for 48 h and we compared the paracrine activity by western blotting. Furthermore, MI model was created and the animals were divided into sham, MI, pre-treated BMSCs, and pre-treated MenSCs groups. The stem cells were administrated via tail vain. 35 days post-MI, serum and tissue were harvested for further investigations.

Results
Following pre-treatment, vascular endothelium growth factor, hypoxia-inducible factor-1, stromal cell-derived factor-1, and hepatocyte growth factor were significantly increased in secretome of MenSCs in compared to BMSCs. Moreover, systemic administration of pre-treated MenSCs, leaded to improvement of cardiac function, preservation of myocardium from further subsequent injuries, promotion the angiogenesis, and reduction the level of NF-κB expression in compared to the pre-treated BMSCs. Also, pre-treated MenSCs administration significantly decreased the serum level of Interleukin 1 beta (IL-1β) in compared to the pre-treated BMSCs and MI groups.

Conclusions
bFGF and 5-aza pre-treated MenSCs offer superior cardioprotection compare to bFGF and 5-aza pre-treated BMSCs following MI.
Association of Phenotypic Aging Marker with comorbidities, frailty and inflammatory markers in people living with HIV
Authors: Han Win Min , Apornpong Tanakorn , Gatechompol Sivaporn , Ubolyam Sasiwimol , Chattranukulchai Pairoj , Wattanachanya Lalita , Siwamogsatham Sarawut , Kerr Stephen J. , Erlandson Kristine M. , Avihingsanon Anchalee 
Published: December 2022

Abstract
Background
Aging characteristics in people living with HIV (PLWH) are heterogeneous, and the identification of risk factors associated with aging-related comorbidities such as neurocognitive impairment (NCI) and frailty is important. We evaluated predictors of novel aging markers, phenotypic age (PhenoAge) and phenotypic age acceleration (PAA) and their association with comorbidities, frailty, and NCI.

Methods
In a cohort of PLWH and age- and sex-matched HIV-negative controls, we calculated PhenoAge using chronological age and 9 biomarkers from complete blood counts, inflammatory, metabolic-, liver- and kidney-related parameters. PAA was calculated as the difference between chronological age and PhenoAge. Multivariate logistic regression models were used to identify the factors associated with higher (>median) PAA. Area under the receiver operating characteristics curve (AUROC) was used to assess model discrimination for frailty.

Results
Among 333 PLWH and 102 HIV-negative controls (38% female), the median phenotypic age (49.4 vs. 48.5 years, p = 0.54) and PAA (− 6.7 vs. -7.5, p = 0.24) was slightly higher and PAA slightly less in PLWH although this did not reach statistical significance. In multivariate analysis, male sex (adjusted odds ratio = 1.68 [95%CI = 1.03–2.73]), current smoking (2.74 [1.30–5.79]), diabetes mellitus (2.97 [1.48–5.99]), hypertension (1.67 [1.02–2.72]), frailty (3.82 [1.33–10.93]), and higher IL-6 levels (1.09 [1.04–1.15]), but not HIV status and NCI, were independently associated with higher PAA. PhenoAge marker discriminated frailty better than chronological age alone (AUROC: 0.75 [0.66–0.85] vs. 0.65 [0.55–0.77], p = 0.04). In the analysis restricted to PLWH, PhenoAge alone predicted frailty better than chronological age alone (AUROC: 0.7412 vs. 0.6499, P = 0.09) and VACS index (AUROC: 0.7412 vs. 0.6811, P = 0.34) despite not statistically significant.

Conclusions
While PLWH did not appear to have accelerated aging in our cohort, the phenotypic aging marker was significantly associated with systemic inflammation, frailty, and cardiovascular disease risk factors. This simple aging marker could be useful to identify high-risk PLWH within a similar chronological age group.