bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design, synthesis, and properties of soluble intrinsic black polyimide bearing tetraphenylcyclopentadienone units
Authors: Tan Jinghua , Shen Junyi , Huang Jie , Yuan Jiazhen , Liu Xueyuan , Li Huipeng , Xie Fengyun , Zhao Chunbo , Liu Yiwu 
Published: August 2023

AbstractBlack polyimides (BPIs) have gained increasing attention because of their growing demands in optoelectronic areas. However, the commonly used BPI containing carbon black suffers from the decreases of mechanical and electrical performances. In this work, a soluble intrinsic BPI (TPCPDFPPI) was prepared by the reaction of 4,4′‐(hexafluoroisopropylidene) diphthalic anhydride (6FDA) and a new diamine (TPCPDFPDA) bearing tetraphenylcyclopentadienone (TPCP) connected with benzene and fluorene units. TPCP grafted with benzene and fluorene units acted as a chromophore that shifted the absorption range of PI toward the long‐wave direction. The resulting TPCPDFPPI possessed whole visible‐light absorption characteristic and therefore exhibited high blackness and opacity. Additionally, TPCPDFPPI displayed superior solubility, mechanical and electrical performance. Theoretical calculations exhibited that the visible‐light absorption responsible for the blackness of TPCPDFPPI was chiefly ascribed to the HOMO to LUMO electron transition in the diamines, where the electrons were primarily migrated from the 2,5‐position aryl groups to the cyclopentadienone. This work offers a promising strategy for improving the overall properties of BPIs for photo‐electronic areas.
Advances of phytotherapy in ischemic stroke targeting PI3K/Akt signaling
Authors: Liu Tianlong , Wang Wenjun , Li Xiaolin , Chen Yidan , Mu Fei , Wen Aidong , Liu Minna , Ding Yi 
Published: August 2023

AbstractThe pathogenesis of ischemic stroke is complex, and PI3K/Akt signaling is considered to play a crucial role in it. The PI3K/Akt pathway regulates inflammation, oxidative stress, apoptosis, autophagy, and vascular endothelial homeostasis after cerebral ischemia; therefore, drug research targeting the PI3K/Akt pathway has become the focus of scientists. In this review, we analyzed the research reports of antiischemic stroke drugs targeting the PI3K/Akt pathway in the past two decades. Because of the rich sources of natural products, increasing studies have explored the value of natural compounds, including Flavonoids, Quinones, Alkaloids, Phenylpropanoids, Phenols, Saponins, and Terpenoids, in alleviating neurological impairment and achieved satisfactory results. Herbal extracts and medicinal formulas have been applied in the treatment of ischemic stroke for thousands of years in East Asian countries. These precious clinical experiences provide a new avenue for research of antiischemic stroke drugs. Finally, we summarize and discuss the characteristics and shortcomings of the current research and put forward prospects for further in‐depth exploration.
The aesthetics of sustainable industrial design: Form and function in the circular design process
Authors: Sareh Pooya 
Published: August 2023

AbstractThe relationship between form and function has long been a point of debate in the design community. Particularly, the famous principle ‘form follows function’ has been a focal point of such discussions. Since its introduction, many studies have been undertaken by theorists and practitioners to challenge or disprove this injunction. Furthermore, from the modern perspective of sustainability which has attracted global attention over the past few decades, there is a crucial link between design and sustainability. That is, poor designs, generally, lead to poor products which contribute to environmental and economic degradation. Consequently, understanding the relationship between form and function in design could contribute to a more sustainable environment. In this paper, first, we explore the views of some influential figures of the twentieth century's industrial design on this essentially philosophical, yet practically crucial, axiom of modernism. Then, we propose a design process model for aesthetic‐sustainable industrial design drawing on a theory of design aesthetics and the principles of circular design. This model integrates a circular design module into the industrial designer's theory of aesthetics to complement the design process in terms of sustainability. The proposed design process model could help designers establish an appropriate relationship between the form and the intended function of a product to contribute to lowering its environmental impact.
Evaluation of soil arsenic pollution and phytoaccumulation capabilities of 24 indigenous plant species in Barak Valley, South Assam, India
Authors: Barhai Akan , Das Suchismita 
Published: August 2023

AbstractThis study investigated the concentrations of arsenic (As) in soil and plant biomass from the Barak Valley in South Assam, India. Soil samples showed concentrations ranging from 6.06 ± 0.84 mg/kg to 18.61 ± 1.52 mg/kg, with an average of 10.60 ± 3.15 mg/kg, 41.67% of the sample exceeding uncontaminated ranges (0.1–10 mg/kg). Ecological risk assessments such as contamination factors, pollutant load index, geo‐accumulation index, and anthropogenicity identified varying contamination levels across sampling points. A total of 24 plant species were collected, ferns (two species), shrubs (five species), grass (six species), and herb (11 species). The concentration of As in different plants types decreased in the order of fern (393.45 ± 159.63 mg/kg) > shrub (20.48 ± 7.25 mg/kg) > herb (17.92 ± 13.75 mg/kg) > grass (14.98 ± 13.80 mg/kg). Plant species, namely Pityrogramma calomelanos, Christella dentata, Mimosa pudica, Chromolaena odorata, Leucas aspera, Persicaria decipiens, Melastoma malabathricum, and Clerodendrum infortunatum, accumulated higher concentrations of As in their above‐ground parts compared to roots and were categorized as tolerant accumulators (TF > 1). By incorporating these plant species into phytoextraction strategies, the region can benefit from their unique properties and abilities to effectively remediate arsenic‐contaminated sites, ultimately improving the affected areas' environmental and human health conditions.
Oestrus ovis sinusitis in a dog
Authors: Azoulay Florian , Girard Nicolas , Gatel Laure , Besson Julie , Fritz Julien 
Published: August 2023

AbstractA 2‐year‐old, female Cane Corso was presented for chronic epistaxis, reverse sneezing and purulent nasal discharge. Clinical examination was unremarkable. Bloodwork revealed a mild anaemia. Computed tomography of the nasal cavity was consistent with right frontal sinusitis with suspected foreign bodies. Surgical approach of the right sinus by frontal osteotomy allowed to perform an endoscopically guided extraction of a 15‐mm white ringed worm and multiple black worm‐like structures. The evaluation by an EVPC diplomate confirmed an Oestrus ovis infestation. After endoscopic lavage of the frontal sinus, the dog went home with an ivermectin‐based treatment. It was presented 7 months later for a recurrence of the clinical signs. Tomography and surgical approach to the right frontal sinus revealed persistent presence of the O. ovis infestation. After surgical removal of the parasite and oral isoxazoline treatment, the dog had no signs of clinical recurrence. Follow‐up computed tomography scan confirmed complete resolution of the sinusitis.
An analytical frequency‐domain model of aerodynamic mass and damping of floating wind turbines
Authors: Yang Can , Xiao Longfei , Chen Peng , Cheng Zhengshun , Liu Mingyue , Liu Lei 
Published: August 2023

AbstractThe fore‐aft motion of the rotor‐nacelle assembly (RNA) of a rotating floating wind turbine (FWT) can cause an oscillation in aerodynamic thrust, which may be equivalently treated as frequency‐dependent aerodynamic mass and damping effects. In this study, an explicit frequency‐domain analytical model is proposed to calculate the equivalent aerodynamic mass and damping of FWTs, with proper linearization of control system. Assuming that an FWT operates under steady wind conditions and a forced oscillation is exerted at the RNA along the wind direction, the thrust fluctuations are equivalently represented by the force and moment acting on the nacelle instead of pure aerodynamic loads. Based on the thrust oscillation expression, equivalent aerodynamic mass and damping are derived analytically. After verifying the model by numerical comparison, it is used to demonstrate equivalent aerodynamic mass and damping of three wind turbines (5–15 MW). Effects of wind turbine up‐scaling and controller dynamics are addressed. Results show that equivalent aerodynamic mass and damping present a nonlinear characteristic with oscillation frequency in the below‐rated region, while the relationship is close to linear for higher wind speeds. The effect of wind turbine up‐scaling has a visible impact on equivalent aerodynamic mass and damping, especially at near‐rated wind speed. Controller gains affect equivalent aerodynamic mass and damping and should be tuned reasonably in the controller design for FWTs. Outcomes of our study can be used to establish a frequency‐domain coupled model of FWTs and are beneficial for conceptual design and parameter optimization of the platform of FWTs.
What Makes Problem-Solving Practice Effective? Comparing Paper and AI Tutoring
Authors: Borchers Conrad , Carvalho Paulo F. , Xia Meng , Liu Pinyang , Koedinger Kenneth R. , Aleven Vincent 
Published: August 2023

AbstractIn numerous studies, intelligent tutoring systems (ITSs) have proven effective in helping students learn mathematics. Prior work posits that their effectiveness derives from efficiently providing eventually-correct practice opportunities. Yet, there is little empirical evidence on how learning processes with ITSs compare to other forms of instruction. The current study compares problem-solving with an ITS versus solving the same problems on paper. We analyze the learning process and pre-post gain data from N = 97 middle school students practicing linear graphs in three curricular units. We find that (i) working with the ITS, students had more than twice the number of eventually-correct practice opportunities than when working on paper and (ii) omission errors on paper were associated with lower learning gains. Yet, contrary to our hypothesis, tutor practice did not yield greater learning gains, with tutor and paper comparing differently across curricular units. These findings align with tutoring allowing students to grapple with challenging steps through tutor assistance but not with eventually-correct opportunities driving learning gains. Gaming-the-system, lack of transfer to an unfamiliar test format, potentially ineffective tutor design, and learning affordances of paper can help explain this gap. This study provides first-of-its-kind quantitative evidence that ITSs yield more learning opportunities than equivalent paper-and-pencil practice and reveals that the relation between opportunities and learning gains emerges only when the instruction is effective.
Women’s right to property and the child quantity-quality trade-off: evidence from India
Authors: Tandel Vaidehi , Dutta Arnab , Gandhi Sahil , Narayanan Ashwini 
Published: August 2023

AbstractWe study the effects of a series of state and federal reforms that granted Indian women equal inheritance rights on the quantity and quality of children. Using a difference-in-differences methodology, we find that women who were affected by the state reforms had 0.4 more children. State reforms did not have any effect on children’s heights. To assess the impact of the federal reform, we use panel data on women and a novel treatment based on the timing of their fathers’ deaths. We find that women affected by the reform had on average 0.22 fewer children and had taller children on average. While the federal reform had no effect on the number of daughters born to this group, the number of sons born declined. Thus, we see evidence that granting property rights to women could potentially impact fertility decisions, children’s health outcomes, and gender imbalance.
Influence of the deposition pattern on the interlayer fracture toughness of FDM components
Authors: Lambiase Francesco , Stamopoulos Antonios G. , Pace Francesco , Paoletti Alfonso 
Published: August 2023

AbstractThe present work is aimed at studying the influence of the deposition strategy on the fracture toughness behavior of the inter-layer zone of fused deposition modeling (FDM) 3D-printed parts. Double cantilever beam (DCB) specimens were produced and tested following recognized testing protocols to capture the fracture toughness behavior. The tested conditions involved linear patterns with monodirectional and alternate infill strategies. The difference in the mechanical behavior of the samples was crossed with optical microscopy observations that also enabled the precise quantification of the effective bonding area between consecutive layers. The results indicated that the deposition pattern dramatically influenced the fracture toughness behavior of these components. Monodirectional deposition strategies involved a fracture toughness within 0.75 and 2.4 kJ/m2 for 0° and 90° raster angles, respectively. On the other hand, the fracture toughness of samples manufactured with alternate deposition strategies more than doubled the values mentioned above, being 2 kJ/m2 and 3.9 kJ/m2 for 0/90° and ±45° deposition strategies, respectively, significantly affecting the failure mode as well. These differences become even more evident if the effective bonding area between consecutive layers is considered.
Homogenization and Phase Separation with Space Dependent Wells: The Subcritical Case
Authors: Cristoferi Riccardo , Fonseca Irene , Ganedi Likhit 
Published: August 2023

AbstractA variational model for the interaction between homogenization and phase separation is considered. The focus is on the regime where the latter happens at a smaller scale than the former, and when the wells of the double well potential are allowed to move and to have discontinuities. The zeroth and first order$$\Gamma $$Γ-limits are identified. The topology considered for the latter is that of two-scale, since it encodes more information on the asymptotic local microstructure. In particular, when the wells are non-constant, the first order$$\Gamma $$Γ-limit describes the contribution of microscopic phase separation, even in situations where there is no macroscopic phase separation. As a corollary, the minimum of the mass constrained minimization problem is characterized, and it is shown to depend on whether or not the wells are discontinuous. In the process of proving these results, the theory of inhomogeneous Modica Mortola functionals is strengthened.
Ulam stability of lamplighters and Thompson groups
Authors: Fournier-Facio Francesco , Rangarajan Bharatram 
Published: August 2023

AbstractWe show that a large family of groups is uniformly stable relative to unitary groups equipped with submultiplicative norms, such as the operator, Frobenius, and Schattenp-norms. These include lamplighters$$\Gamma \wr \Lambda $$Γ≀Λwhere$$\Lambda $$Λis infinite and amenable, as well as several groups of dynamical origin such as the classical Thompson groups$$F, F', T$$F,F′,TandV. We prove this by means of vanishing results in asymptotic cohomology, a theory introduced by the second author, Glebsky, Lubotzky and Monod, which is suitable for studying uniform stability. Along the way, we prove some foundational results in asymptotic cohomology, and use them to prove some hereditary features of Ulam stability. We further discuss metric approximation properties of such groups, taking values in unitary or symmetric groups.
Can acetate via FFA receptors contribute to the diabetogenic effect of statins?
Authors: Levy Finn Olav , Osnes Jan-Bjørn 
Published: August 2023

AbstractDespite the proven effects of statins in preventing cardiovascular disease, their diabetogenic effect has caused concern. The mechanism of this diabetogenic effect is unknown. We suggest a novel mechanism that may contribute to the diabetogenic effect of statins, through an effect of statins that has apparently escaped previous consideration. Briefly, by inhibiting HMG-CoA reductase, statins may cause accumulation of acetate, which through FFA2 and FFA3 stimulation may inhibit insulin secretion.
Development of plasmid calibrators for absolute quantification of the β-parvalbumin gene in Lophius piscatorius
Authors: Mukherjee Subham , Hanak Petr , Zdenkova Kamila , Musilova Zuzana , Horka Petra , Jilkova Diliara , Cermakova Eliska 
Published: August 2023

AbstractThe real-time quantitative PCR (qPCR) calibration curves are highly reproducible and allow the generation of specific, sensitive, and reproducible data that can be used for gene quantification. However, it is important to rigorously validate the external calibration curve model in qPCR since absolute quantification is dependent on the standards used. We present a method for standardising qPCR-based quantification of the β-parvalbumin (β-pvalb) gene of Lophius piscatorius, a major fish allergen, using a plasmid DNA (pDNA) calibrator. In parallel experiments, standard curves were generated and compared from the genomic DNA (gDNA) isolated from L. piscatorius and pDNA carrying the target, pvalb. The commutability of pDNA and gDNA calibrators for the quantification of β-pvalb was assessed by employing a TaqMan qPCR, targeting the second intron of the pvalb gene of L. piscatorius. Higher PCR efficiencies, good linearity, and lower standard deviation (S.D.) values were observed with pDNA instead of gDNA calibrants. pDNA calibrants exhibited a lower bias in terms of closeness to the expected value of unknown samples than their genomic counterparts. The assay was specific and sensitive, where the limit of detection (LOD) and limit of quantification (LOQ) were five copies and ten copies per reaction. The short-term stability study of the pDNA calibrants indicated its stability for 60 days at − 20 °C and 30 days at 4 °C. The efficient results indicated a plasmid calibrator as a potential tool for absolute quantification of the pvalb gene and an alternative to conventional gDNA standards.
Pre-pectoral Breast Reconstruction: Surgical and Patient-Reported Outcomes of Two-Stages vs Single-Stage Implant-Based Breast Reconstruction
Authors: Zingaretti Nicola , Piana Michele , Battellino Laura , Galvano Francesca , De Francesco Francesco , Riccio Michele , Beorchia Yvonne , Castriotta Luigi , Parodi Pier Camillo 
Published: August 2023

Abstract
Background
Two-stages pre-pectoral breast reconstruction may confer advantages over direct to implant (DTI) and subpectoral reconstruction in selected patients who have no indication for autologous reconstruction. The primary endpoint of the study was to evaluate and compare the incidence of capsular contracture in the pre-pectoral two-stages technique versus the direct to implant technique. Complications related to the two surgical techniques and patient satisfaction were also evaluated.

Methods
A retrospective review of 45 two stages and 45 Direct-to-implant, DTI patients was completed. Acellular dermal matrix was used in all patients. An evaluation of anthropometric and clinical parameters, surgical procedures and complications was conducted. Minimum follow-up was 12 months after placement of the definitive implant.

Results
There was no statistically significant difference in the rate of capsular contracture in the two groups. Rippling occurred more in DTI reconstruction. In the two-stages reconstruction, lipofilling was applied more often and there was a higher incidence of seroma. Patient satisfaction extrapolated from the Breast Q questionnaire was better for patients submitted to two-stage implant-based breast reconstruction.

Conclusion
Dual-stage pre-pectoral reconstruction with acellular dermal matrix appears to be a good reconstructive solution in patients with relative contraindications for one-stage heterologous reconstruction with definitive prosthesis and no desire for autologous reconstruction.
Comparative In Vivo Study of Solid-Type Pure Hyaluronic Acid in Thread Form: Safety and Efficacy Compared to Hyaluronic Acid Filler and Polydioxanone Threads
Authors: Kim Jong-Ho , Han Man Wong , Lee Myoung-Han , Kweon Dong-Keon , Park Young Jin , Heo Chan Yeong 
Published: August 2023

Abstract
Introduction
Although various products are commonly used for skin rejuvenation, solid-type hyaluronic acid (HA) as an injectable form has not been researched or utilized. This study aimed to demonstrate the safety and efficacy of solid-type HA in thread form, which differs from the conventional gel-type HA commonly used.

Method
Solid-type HA threads, conventional HA fillers, and polydioxanone (PDO) threads were inserted into the dorsal subcutaneous layer of mice. Photographs were taken on days 0, 1, 3, and 7, and on day 7, the samples were harvested for histological analysis. Inflammatory reactions and detection of collagen were confirmed through tissue staining, and real-time PCR was conducted to quantify collagen synthesis.

Results
In the histological analysis, the PDO threads exhibited a greater inflammatory response compared to the HA threads. Masson’s trichrome staining revealed a higher degree of collagen synthesis in the HA thread group compared to the HA filler group. While collagen type 1 expression was significantly higher in the PDO thread group than in the HA thread group, the HA thread group showed higher expression levels of collagen type 3. Furthermore, the PDO thread group demonstrated a statistically significant increase in TGF-β1 compared to the HA group.

Conclusion
This in vivo study demonstrated the stable application of solid-type pure HA threads and their potential for inducing collagen production, while also yielding a low inflammatory response. The findings highlight the promising applications of solid-type HA in the field of cosmetic dermatology.

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