bluuebunny/crossref_metadata_2025_split huggingface dataset:
The “best practices for farming” successfully contributed to decrease the antibiotic resistance gene abundances within dairy farms
Authors: Salerno Barbara , Cornaggia Matteo , Sabatino Raffaella , Di Cesare Andrea , Mantovani Claudio , Barco Lisa , Cordioli Benedetta , Bano Luca , Losasso Carmen 
Published: January 2025

IntroductionFarms are significant hotspots for the dissemination of antibiotic-resistant bacteria and genes (ARGs) into the environment and directly to humans. The prevalence of ARGs on farms underscores the need for effective strategies to reduce their spread. This study aimed to evaluate the impact of a guideline on “best practices for farming” aimed at reducing the dissemination of antibiotic resistance.MethodsA guideline focused on prudent antibiotic use, selective therapy, and hygienic and immune-prophylactic practices was developed and provided to the owners of 10 selected dairy farms and their veterinarians. Fecal samples were collected from lactating cows, dry cows, and calves both before and after the implementation of the guideline. ARGs (blaTEM, ermB, sul2, and tetA) were initially screened by end-point PCR, followed by quantification using digital droplet PCR. ARG abundance was expressed in relative terms by dividing the copy number of ARGs by the copy number of the 16S rRNA gene.ResultsThe ARG abundances were higher in lactating cows compared to other categories. Despite similar levels of antibiotic administration (based on veterinary prescription data from the sampled farms) in both sampling campaigns, the total abundance of selected ARGs, particularly blaTEM and tetA, significantly decreased after the adoption of the farming guidelines.DiscussionThis study highlights the positive impact of prudent antibiotic use and the implementation of farming best practices in reducing the abundance of ARGs. The lactating cow category emerged as a crucial point of intervention for reducing the spread of antibiotic resistance. These findings contribute to ongoing efforts to address antibiotic resistance in farm environments and strengthen the evidence supporting the adoption of good farming practices.
Mechanical evaluation of mandibular fractures stabilized with absorbable implants or intraoral splints in cats
Authors: Castejon-Gonzalez Ana C. , Friday Chet S. , Hast Michael W. , Reiter Alexander M. 
Published: January 2025

IntroductionThe goal of this cadaver study in cats was to compare the mechanical properties of intact mandibles (C) with mandibles whose simulated fracture was located between the third and fourth premolar teeth and repaired with four possible treatments: (1) Stout multiple loop interdental wiring plus bis-acryl composite intraoral splint (S); (2) modified Risdon interdental wiring plus bis-acryl composite intraoral splint (R); (3) ultrasound-aided absorbable fixation plate (P); and (4) ultrasound-aided absorbable fixation mesh (M).Materials and methodsThirty feline mandibles were randomly assigned to the control and treatment groups. Mandibles were loaded by cantilever bending on the canine tooth, first in non-destructive cyclic loading followed by destructive ramp-to-failure loading.ResultsCyclic loading showed no differences between the treatment groups in angular deflection (a measure of sample flexion under non-destructive loads); however, the R group had significantly higher angular deflection than the C group. In destructive testing, no differences in mechanical properties were found between the treatment groups; however, all treatment groups demonstrated significantly lower maximum bending moment, bending stiffness, energy to failure, and maximum force when compared to the control group. The main mode of failure of the intraoral splint groups (S and R) was fracture of the bis-acryl composite (50%), and the main mode of failure of the absorbable fixation groups (P and M) was fracture of the pins (91.7%).DiscussionIntraoral splint and absorbable fixation methods have low strength and stiffness. The four treatments tested provided similar stabilization of mandibular fractures located between the third and fourth premolar teeth.
Synergetic Effects of Coffea liberica and Curcuma zanthorrhiza: Study of Sensory Profile, Proximate, and Chemical Compound
Authors: Latief Madyawati , Muntasir Retno Widya , Wijaya Dhian Eka , Tarigan Indra Lasmana , Sutrisno Sutrisno 
Published: January 2025

Liberica coffee (Coffea liberica) thrives on peat soil, unlike Arabica and Robusta, making it an essential commodity in Jambi, Indonesia, where it is known as Liberika Tungkal Komposit (Libtukom) and serves as a primary livelihood. This low-caffeine coffee has a higher economic value than high-caffeine varieties. Adding spices such as temulawak (Curcuma zanthorrhiza) to Liberica coffee can create a unique, functional beverage with new aromas and health benefits, thanks to the curcuminoid antioxidants in Curcuma zanthorrhiza (C. zanthorrhiza). This research aims to develop a spice-infused Liberica coffee with enhanced sensory qualities and health benefits. Methods include spice coffee formulation; sensory evaluation; phytochemical screening; and analysis of phenolics, flavonoids, antioxidants, caffeine, and chlorogenic acid levels. Statistical analysis (ANOVA and Duncan’s post hoc test) reveals that C. zanthorrhiza-enhanced Liberica coffee is preferred by panelists, with spice coffee outperforming plain Liberica in sensory tests. This study showed that Liberica coffee mixed with C. zanthorrhiza affected the sensory performance of Liberica coffee, where the coffee most favored by panelists was spice coffee. Based on the cupping test results, spice coffee had excellent results, while Liberica coffee had very good results. The phytochemical analysis revealed that coffee–C. zanthorrhiza exhibited higher concentrations of total phenolics, flavonoids, and antioxidant activity than the original Liberica coffee. However, the caffeine and chlorogenic acid levels in all spiced coffee were lower compared to the original Liberica coffee.
Crown Gall Induced by a Natural Isolate of Brucella (Ochrobactrum) pseudogrignonense Containing a Tumor-Inducing Plasmid
Authors: Hooykaas Marjolein J. G. , Hooykaas Paul J. J. 
Published: January 2025

Crown gall disease in plants is caused by “Agrobacteria”, bacteria belonging to the Rhizobiaceae family, which carry a tumor-inducing (Ti) plasmid. Unexpectedly, we found evidence that a natural isolate from a rose crown gall, called NBC51/LBA8980, was a bacterium that did not belong to the Rhizobiaceae family. Whole-genome sequencing revealed that this bacterium contained three large DNA circles with rRNA and tRNA genes, representing one chromosome and two chromids, respectively, and two megaplasmids, including a Ti plasmid. Average nucleotide identity (ANIb, ANIm) and genome-to-genome distance (GGDC) values above the thresholds of 96% and 70%, respectively, showed that NBC51/LBA8980 belonged to the species Brucella (Ochrobactrum) pseudogrignonense. Its Ti plasmid was almost identical to certain succinamopine Ti plasmids previously identified in Agrobacterium strains, suggesting that this Ti plasmid may have been recently acquired by NBC51/LBA8980 in the tumor environment.
Determinación de la calidad de la leche del ganado bovino en el municipio de Tarímbaro Michoacán
Authors: Cedeño José Luis Carlos Bedolla , Domínguez Rodolfo Lucio , Hernández Ángel Raúl Cruz , Sandoval Jorge Arturo Arana , Chávez Manuel Chávez , García José Carlos Bedolla , Izquierdo Alejandro Córdova 
Published: January 2025

El objetivo del presente trabajo fue determinar la calidad de la leche del ganado bovino en el municipio de Tarímbaro, Michoacán. El trabajo se realizó de Septiembre a Diciembre de 2012 en el municipio de Tarímbaro, Michoacán con 100 hatos lecheros de la raza Holstein Friesian y criollo. Se tomó una muestra de leche del bote de recepción de cada hato, las cuales fueron transportadas al laboratorio de bacteriología de la FMVZ de la UMSNH para su procesamiento. Se encontró que el 70% de las muestras cumplen con lo establecido en la Norma NMX-F-700-COFOCALEC-2004, mientras que el resto (30%) no cumple. Respecto a la Norma México Calidad Suprema 2007, el 29% de las muestras cumple con lo que ésta señala, no así el resto (61%). Se concluye que la calidad de la leche en este municipio de acuerdo a la norma F 700 es en un 70% de buena calidad, y de acuerdo a la norma México Calidad Suprema, solamente el 29% es apta para su consumo.
Assessing the Vitamin-D (Calciferol) Supplementation Impact on Glycemic Levels among Patients with Type-2 Diabetes (DM-2); A Quasi-Experimental Trial
Authors: Ghafoor Adnan , Sarfraz Maria , Kalsoom Maria , Noureen Sadaf , Fatima Hareem , Hasan Kazmi Syed Kumail 
Published: January 2025

Background: Calciferol has vital role in maintenance of glucose levels by its action on VDR receptors which are located on beta cells of the pancreas after that leading to the surge in insulin secretion as well as improvement of insulin sensitivity offered by an increased expression of insulin receptors
Objective: To determine the effect of Vitamin-D (calciferol) on the control of blood glucose (measured in terms of mean reduction of ≥1 in HbA1c) in calciferol deficient and insufficient diabetics, who have poorly controlled DM-2
Methodology: A Quasi-Experimental trial at the Department of Medicine, Fauji Foundation Hospital, Rawalpindi for 06 months was conducted after, meeting inclusion and exclusion criteria. 115 patients were enrolled and effect of calciferol on levels of blood glucose was assessed by measuring HbA1c levels, and pre-& post calciferol supplementation.
Results: Results showed mean of ages was 57.80 ± 7.64 years, 39(33.91%) patients were male and 76(66.09%) patients were females. On pre-intervention, the mean HbA1C of the patients who participated was 7.99 ± 0.48 while on post-intervention the mean HbA1C of the patients was 7.97 ± 0.48 (p-value=0.7523).
Conclusion: Effect of calciferol on glycemic control (measured in terms of mean reduction of ≥1 in HbA1c) in calciferol-deficient and insufficient diabetics was insignificant. Therefore, vitamin D supplementation appears to have no effect on blood glucose control in diabetes individuals who have low levels of calciferol—both inadequate and deficient—both of which are low.

Keywords: Calciferol (Vitamin-D), Levels of blood sugar, Poorly Controlled Type-2 Diabetes
Sistem Pendukung Keputusan Pemilihan Hanphone Menggunakan Metode Oreste
Authors: Radika Radika , Kiswanto Rahmat H. , Irjanto Nourman S. 
Published: January 2025

<p><em>Thedevelopment of mobile phones is very rapid in the city of Jayapura, it is undeniable that the daily lives of people from various professions are very dependent on mobile phones. Some mobile phone users admit to choosing the wrong mobile phone because they do not know what they should consider when choosing the right mobile phone for their needs. This study aims to build a mobile phone selection decision support system so that consumers can choose mobile phones better and more efficiently. The method used in this study is the Oreste Method with the selection of weighted criteria such as price, ram / rom, camera, chipset, screen, and battery to determine consumer selection. The results of this study are expected to help recommend to consumers in the selection of mobile phones according to consumer wishes such as the selection of Redmi M4 pro mobile phones as the mobile phones with the best selection on this system with a preference value of 7.52465857</em></p><p><strong><em>Keyword</em></strong><strong><em>:</em></strong><em> Decision Support System; Oreste Method; Selection Cellphone</em></p><p align="right"><em> </em></p><p align="center"><strong>Abstrak</strong></p><p>Perkembangan <em>handphone</em> sangat pesat di kota Jayapura, sulit dipungkiri bahwa kehidupan sehari-hari orang-orang dari berbagai profesi sangat bergantung pada <em>handphone</em>. Beberapa pengguna <em>handphone</em> mengaku salah memilih <em>handphone </em>karena mereka tidak tahu apa yang harus mereka pertimbangkan saat memilih <em>handphone</em> yang tepat untuk kebutuhan mereka. Maka Penelitian ini bertujuan untuk membangun sistem pendukung keputusan pemilihan <em>handphone</em> agar para konsumen dapat memilih <em>handphone</em> dengan lebih baik dan efisien. Metode yang digunakan pada penelitian ini adalah Metode <em>Oreste</em> dengan pemilihan bobot kriteria seperti harga, ram/rom, kamera, <em>chipset</em>, layar, dan baterai untuk menentukan pemilihan konsumen. Hasil dari penelitian ini Diharapkannya dapat membantu merekomendasikan pada konsumen dalam pemilihan <em>handphone</em> sesuai keinginan konsumen seperti terpilihnya <em>handphone Redmi</em> M4 pro sebagai <em>handphone</em> dengan pemilihan terbaik pada sistem ini dengan nilai preferensi 7.52465857.</p><p> </p>
Penerapan Customer Relationship Management Pada Klinik K-Skincare Berbasis Android
Authors: Erlansyah Deni , Hersani Rizal 
Published: January 2025

<p><em>Currently, the K-Skincare Clinic has not fully used information technology, for example to make reservations, marketing and maintain relationships between clinics and customers. To overcome this, it is necessary to have an application that can implement Customer Relationship Management (CRM) which is able to provide solutions to maintain quality and customer loyalty at the K-Skincare Clinic and make it easier to access information. This study aims to create an android-based K-Skincare Clinic application using the Extreme Programming (XP) method which is expected to be able to provide solutions to maintain quality and customer loyalty at the K-Skincare Clinic and make it easier to access information through the K-Skincare Clinic application. The results obtained are the Android-based K-Skincare Clinic application which can be used for product purchases, treatment reservations, chats, customer reviews, my favorites and notifications.</em></p><p><strong><em>Keywords:</em></strong><em> system; Customer Relationship Management (CRM); androids; K-Skincare Clinic</em></p><p><em> </em></p><p align="center"><strong><em>Abstrak</em></strong></p><p>Saat ini Klinik K-Skincare belum sepenuhnya menggunakan teknologi informasi contohnya untuk melakukan reservasi, pemasaran dan menjaga hubungan antara klinik dan pelanggan saat ini hanya mengandalkan sosial media seperti <em>facebook, instagram </em>dan <em>whatsApp</em> yang dirasa masih kurang efektif yaitu keterbatasan mengelola data pelanggan dan transaksi. untuk mengatasi hal tersebut diperlukan adanya aplikasi yang dapat menerapkan <em>Customer Relationship Management (CRM)</em> yang mampu memberikan solusi mempertahankan kualitas dan loyalitas terhadap pelanggan pada Klinik K-Skincare dan mempermudah dalam mengakses informasi. Penelitian ini bertujuan untuk membuat aplikasi Klinik K-Skincare berbasis android dengan menggunakan metode <em>Extreme Programming (XP)</em> yang diharapkan mampu memberikan solusi mempertahankan kualitas dan loyalitas terhadap pelanggan pada Klinik K-Skincare dan mempermudah dalam mengakses informasi melalui aplikasi Klinik K-Skincare. Hasil yang didapat adalah aplikasi Klinik K-Skincare berbasis android yang dapat digunakan untuk pembelian produk, reservasi <em>treatment, chatt, customer review, favorit saya dan notifikasi</em>.</p><p> </p>
Perancangan Aplikasi Point of Sales Restoran Berbasis Web untuk Perusahaan Summerrice
Authors: Frederick Thomas , Trisnawarman Dedi , Perdana Novario Jaya 
Published: January 2025

<p><em>Summerrice is a small-scale SME (Small and Medium-sized Enterprise) engaged in the Japanese food and beverage industry. Summerrice restaurant has been in operation since 2018 until 2023. Despite its four years of operation, the restaurant still relies on manual operational records for transactions, inventory, and employee attendance, resulting in a chaotic operational system and significant data loss due to the physical record-keeping that is prone to misplacement. To solve this, a Point of Sales application has been designed to streamline Summerrice restaurant's operational processes, enabling it to run and grow more efficiently with the assistance of this information system program. The development of this program will follow the System Development Life Cycle (SDLC) waterfall model and use the PHP programming language with the CI4 framework, and the database used is MySQL. The application design includes features that facilitate various aspects of the business operations, such as transaction recording, inventory management, and employee attendance.</em></p><p><strong><em>Keywords</em></strong><strong><em>:</em></strong><em> Summerrice; Point of Sales; business operations; information systems; effectiveness</em></p><p align="center"><strong> </strong></p><p align="center"><strong>Abstrak</strong></p><p>Summerrice adalah perusahaan kecil berskala UMKM yang bergerak di bidang makanan dan minuman Jepang. Restoran Summerrice sudah berjalan semenjak tahun 2018 hingga tahun 2023, walaupun restoran Summerrice sudah berjalan selama 4 tahun namun untuk pencatatan operasional masih dilakukan secara manual seperti transaksi, bahan, dan absensi sehingga membuat sistem pekerjaan sisi operasional dari restoran ini berantakan bahkan banyak data yang hilang dikarenakan pencatatan berbentuk fisik yang mudah hilang. Maka dari itu dirancang sebuah aplikasi <em>Point of Sales</em> untuk dijadikan sistem yang membantu operasional dari restoran Summerrice sehingga restoran dapat berjalan dan berkembang lebih cepat dengan bantuan program sistem informasi ini. Pembuatan program ini akan menggunakan <em>System Development Life Cycle</em> (SDLC) model <em>Waterfall</em> dan menggunakan bahasa pemrograman PHP dengan framework CI4 dan database yang digunakan adalah MySQL.Rancangan aplikasi ini memiliki fitur fitur yang membantu sisi operasional bisnis seperti pencatatan transaksi, bahan bahan, absensi pegawai.</p><p> </p>
Implementation Unified Modeling Language in the Development E-mail Application System
Authors: Aprijal Aprijal , Hindarto Djarot 
Published: January 2025

<p><em>In the era of globalization, which is influenced by advances in technology and information, several government institutions, such as Bank XYZ Head Office, still use a semi-computerized approach in the archiving process, especially in documenting incoming and outgoing letters. As a result, data entry errors often occur, resulting in inaccurate reports. To overcome this problem, the author proposes a new method that involves analysis, planning, and design procedures using the PHP programming language and MySQL database, as well as an object-oriented approach by utilizing the Unified Modeling Language during the implementation stage. With this new system, errors in recording incoming and outgoing mail will be reduced, and data processing will become more efficient so that reporting can be consistent with existing data. Application system testing is carried out to determine that the system designed and developed meets the needs of users and company management. From testing these modules, success = 93,33% and failure = 6,67%</em><em>.</em></p><p><strong><em>Keyword</em></strong><strong><em>:</em></strong><em> PHP programming language; Unified Modeling Language; MySQL database </em></p><p align="center"><em> </em></p><p align="center"><strong>Abstrak</strong></p><p><em>Di era globalisasi yang dipengaruhi oleh kemajuan teknologi dan informasi, beberapa institusi pemerintahan seperti Kantor Pusat Bank XYZ masih menggunakan pendekatan semi komputerisasi dalam proses pengarsipan, khususnya dalam pendokumentasian surat masuk dan keluar. Akibatnya, kesalahan entri data sering terjadi sehingga menghasilkan laporan yang tidak akurat. Untuk mengatasi masalah ini, penulis mengusulkan metode baru yang melibatkan prosedur analisis, perencanaan, dan desain menggunakan bahasa pemrograman PHP dan database MySQL serta pendekatan berorientasi objek dengan memanfaatkan Unified Modeling Language selama tahap implementasi. Dengan sistem baru ini diharapkan kesalahan dalam pencatatan surat masuk dan keluar akan berkurang, dan pengolahan data menjadi lebih efisien sehingga pembuatan laporan dapat konsisten dengan data yang ada. Pengujian system aplikasi dilakukan untuk mengetahui bahwa system yang dirancang dan dikembangkan sudah memenuhi kebutuhan user dan manajemen perusahaan. Dari pengujian modul-module tersebut sukses = 93,33% dan gagal = 6,67%.</em></p><p> </p>
Identification of The Causes of Base Rot Disease of Palm Oil in Two Villages in Kampar and Siak Districts of Riau Province
Authors: Elfina Yetti , Irfandri  , Sabirunah Aisyah , Ningsih Widya 
Published: January 2025

Palm oil (Elaeis guineensis Jacq.) is an important plantation crop in Indonesia including in Riau Province. Palm oil productivity in Riau has decreased due to several factors, one of which is disease. An important disease in palm oil plantations is stem base rot (BPB) caused by the fungus Ganoderma sp. This study aims to identify the causes of BPB disease of palm oil in Deli Makmur Village, Kampar Regency and Jati Baru Village, Siak Regency. This research was conducted using survey and observation methods in palm oil plantations in two villages in Kampar and Siak Districts. The identification of pathogens was carried out based on morphological characteristics by making macroscopic and microscopic observations. Initial diagnosis based on symptoms and signs palm oil plants found in Deli Makmur Village and in Jati Baru Village showed symptoms of stem base rot (BPB). The results of morphological identification show that the pathogen causing BPB disease is Ganoderma sp. The macroscopic and microscopic characteristics of the two Ganoderma sp. fungal isolates are slightly different, where the fungal isolate from Deli Makmur Village mycelium grows sideways, has a smooth and very thick texture, there are concentric rings, crystals and cuticular cells. While the mushroom isolate from Jati Baru Village mycelium grows sideways, has a fine texture, is quite thick, and there are no ring-shaped concentric, crystals and cuticular cells.
PENGARUH PERSEPSI DAN RELIGIUSITAS MASYARAKAT TERHADAP MINAT MENABUNG DI BANK SYARIAH
Authors: Nurholisah Salsa , Chumairo Dewy Rahmadanty Musrifa , Permana Rusma 
Published: January 2025

Penelitian ini bertujuan untuk menguji pengaruh secara parsial maupun simultan dari persepsi dan religiusitas masyarakat terhadap minat menabung di bank syariah. Penelitian ini menggunakan metode kuantitatif. Program aplikasi yang digunakan untuk mengolah data yaitu SPSS versi 25. Dalam penelitian ini sampel yang ditetapkan sebanyak 98 orang dengan menggunakan rumus slovin dan pengambilan sampel menggunakan metode probability sampling dengan teknik cluster sampling yang cara pengambilan sampel acak berdasarkan area atau wilayah. Data yang digunakan adalah data primer yang diperoleh dari pembagian kuesioner terhadap masyarakat desa Sukaraja sesuai dengan karakteristik responden yang peneliti tentukan. Pengukuran variabel menggunakan skala Likert dengan skala 1 sampai 5. Pengujian hipotesis dalam penelitian ini menggunakan regresi linear berganda.
Hasil penelitian menunjukan bahwa persepsi berpengaruh secara signifikan terhadap minat menabung masyarakat desa Sukaraja didapat hasil thitung > ttabel (7,048 > 1,984) dengan tingkat signifikansi sebesar 0,000 < 0,05 (5%), religiusitas berpengaruh signifikan terhadap minat menabung masyarakat desa Sukaraja didapat hasil thitung > ttabel (4,060 > 1,984) dengan tingkat signifikansi sebesar 0,000 < 0,05 (5%), persepsi dan religiusitas secara simultan berpengaruh signifikan terhadap minat menabung masyarakat desa Sukaraja didapat hasil fhitung > ftabel yaitu 65,783 > 3,09. Dengan demikian perbankan syariah sangat mudah meningkatkan sosialisasi kepada masyarakat tentang keuangan syariah agar dapat diterima dan dimengerti oleh seluruh masyarakat desa Sukaraja.