bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fostering Positive Stuttering Identities Using Stutter-Affirming Therapy
Authors: Constantino Christopher Dominick 
Published: December 2022

Purpose:
School-age children and adolescents frequently have difficulty developing positive identities around their stuttering. Many students experience both physical and social consequences from stuttering. The great lengths that speakers go to try to hide their stuttering and to speak fluently increase their difficulty. As long as school-age children who stutter try to identify as fluent speakers, they will have difficulty lessening the negative impact of stuttering on their lives. Fortunately, many people who stutter also report positive stuttering experiences. Speech-language pathologists can use these positive experiences to help school-age children grow more comfortable with stuttering. They can also help school-age children reduce some of the speaking effort and social stigma that leads them to try to conceal their stuttering in the first place. To accomplish both these goals, I propose a stutter-affirming therapy.

Method:
This clinical focus article summarizes previous research about identity development in stuttering. I discuss a therapy approach I call stutter-affirming therapy. In elucidating this approach, I discuss practical ways that speech-language pathologists can use to help school-age children develop positive stuttering identities through easier speaking and stuttering. I ground these examples in a case study of a 12-year-old boy who stutters.

Discussion:
stutter-affirming therapy focuses on conditioning the speaker's reaction to stuttering in ways that move toward and embrace stuttering (stutterphilic reactions) rather than in ways that move away from and reject stuttering (stutterphobic reactions). Speech-language pathologists can help school-age children who stutter foster positive stuttering identities using the three priorities of stutter-affirming therapy. First, reject fluency by reducing stutterphobic and increasing stutterphilic reactions to stuttering. Second, value stuttering by discovering what speakers gain from it. Third, create an environment in which it is easier to stutter through education, advocacy, disclosure, and voluntary stuttering.
Robust state and output feedback prescribed performance interval type‐3 fuzzy reinforcement learning controller for an unmanned aerial vehicle with actuator saturation
Authors: Elhaki Omid , Shojaei Khoshnam , Mohammadzadeh Ardashir 
Published: December 2022

AbstractThis paper presents a novel adaptive reinforcement learning control method with interval type‐3 fuzzy neural networks to improve the trajectory tracking control performance of quadrotor unmanned aerial vehicles in challenging flight conditions. The proposed reinforcement learning controller is independent of the system's dynamics, and only relies on measurable signals of the system. An adaptive robust controller in collaboration with the suggested reinforcement learning method is designed to significantly improve the robustness of the control system. The maximum overshoot/undershoot, convergence rate and final tracking accuracy are ensured a priori by the prescribed performance control methodology. To develop the proposed controller and to achieve a high‐performance closed‐loop system, a high‐gain observer is employed in order to estimate the velocity and acceleration of the quadrotor unmanned aerial vehicles system. The uniform ultimate boundedness stability of the proposed control algorithm is achieved by a Lyapunov‐based stability analysis. Finally, in the simulation section, it is shown that the presented intelligent controller with the proposed learning algorithm result in a better performance in contrast to the other kind of conventional control techniques.
Plasma‐activated ethanol solution and it's decontamination effect
Authors: Li YiQian , Liu JiaLin , Zhao Feng , Song Ke , Nie LanLan , Liu DaWei , Lu XinPei 
Published: December 2022

AbstractEthanol solution as a disinfectant has been widely used in various fields. However, it has a significant bactericidal capability only when the volume fraction of ethanol is around 70%–75%. For such high concentration of ethanol solution, it has an irritating smell. When it is used for applications such as wound disinfection, it causes a stinging sensation. Low concentrations of ethanol solution are less irritating, but it is also less effective at killing bacteria. In this study, an idea for producing a green, efficient and less irritating disinfectant is proposed. It is based on a plasma‐activated low‐concentration ethanol solution (PAES). It is found that the plasma‐activated 10% volume fraction of ethanol solution can kill more than seven orders of magnitude of Escherichia coli, while the untreated 10% volume fraction of ethanol solution has no bactericidal effect. Besides, the PAES's activity remains unchanged after being stored at for three days. Further investigation shows that new compositions including peracetic acid, peroxynitrite, hydrogen peroxide and acetic acid are detected in the PAES, which together are playing the main role of the excellent and prolonged bactericidal effect.
Analysis of Flap Failures in Microvascular Head and Neck Reconstructions: 11-Year Single-Center Results
Authors: Jokinen Daria , Kuuskeri Marika , Helminen Mika , Kääriäinen Minna 
Published: December 2022

AbstractBackground Free flap reconstruction is the gold standard in head and neck reconstructions. The current article analyzes failed free flaps in the head and neck region during an 11-year period in a single center aiming to discover factors that could be influenced in order to reduce the risk for flap failure.Methods During the 11-year study period, 336 patients underwent free flap reconstruction at Tampere University Hospital, Tampere, Finland. The patients' average age was 62 years (range 14–92 years). Note that 201 (61.5%) of the patients were women and 135 (38.5%) men. Medical records were reviewed for demographics, comorbidities, neoadjuvant and adjuvant therapies, free flap type, area of reconstruction, and intraoperative and postoperative complications. Statistical analyses were performed.Results Ten (3%) of the 336 free flaps failed. Patients' age, comorbidities, smoking, dosage of anticoagulation, free flap type, or the location of the defect did not influence the risk of flap failure. All lost flaps were postoperatively followed by clinical monitoring only. In contrast, 89% of all flaps had both Licox (Integra LifeSciences Corp, NJ) and clinical follow-up postoperatively. In six (60%) of the failed cases, a second free flap surgery was performed as a salvage procedure, with a survival rate of 83.3%.Conclusion Our free flap success rate of 97% is in accordance with that of other centers that perform head and neck reconstructions. According to our findings, free flap reconstructions can be successfully performed on elderly patients and patients with comorbidities. Smoking did not increase the flap loss rate. We encourage the use of other methods in addition to clinical monitoring to follow the flaps after head and neck free flap reconstructions. All flap types used have high success rates, and reconstruction can be conducted with the most suitable flaps for the demands of the defect.
Preliminary Observation on the Usefulness of Homoeopathic Medicine Lapis albus 30 Centesimal Potency in Hypertriglyceridaemia: A Retrospective Study
Authors: Vinitha Edavattath Ramanan 
Published: December 2022

Abstract
Background Hypertriglyceridaemia is a clinical condition where the serum triglyceride level rises above the normal value of 150 mg/dL. It often leads to cardiovascular diseases, and severe hypertriglyceridaemia increases the risk for pancreatitis. All lipid-lowering drugs used in conventional medicines are reported to have adverse side effects. In this scenario, it is prudent to explore a drug that effectively reduces the triglyceride level, without any side effects, in a relatively shorter time. This study aimed to highlight the action of Lapis albus 30 centesimal (30C) in reducing hypertriglyceridaemia.
Materials and Methods A retrospective study of case records of patients who were under medicine Lapis albus 30C for hypertriglyceridaemia, irrespective of age and gender, in outpatient department of National Homoeopathy Research Institute in Mental Health, Kerala, was done. Pre- and post-intervention fasting lipid profile values were analysed and evaluated for the study.
Result There was a clinically important difference in triglyceride level after administration of Lapis albus 30C in 23 cases out of a total of 25 cases.
Conclusion The present study indicates that the medicine Lapis albus 30C can be useful in reducing hypertriglyceridaemia and lends support for exploring the possibility of this medicine in a larger study sample.
Factor XIII Deficiency Managed With Individualized Homoeopathic Medicine In Intellectually Disabled Child: An Evidence Based Case Report
Authors: Shaikh Afroz , Kundu Tapas , Ghosh Kanjaksha , Kumat Omkar , Mirza Gulfisha 
Published: December 2022

AbstractFactor XIII deficiency is an inherited bleeding disorder, which is rare, ∼1 in 5,000,000, while its combination with an intellectual disability is seldom. It is mostly a result of genetic mutation caused due to consanguineous marriage. Due to deficiency of fibrin stabilising factor, a clot formed is weak and leads to fibrinolysis, which is evident as unstoppable bleeding from umbilical cord stump, epistaxis and bleeding from various organs. The condition is made worst due to intellectual disability as the patient is more prone to injuries due to lack of knowledge of impending dangers. The latest provision of gene therapy is yet to be achieved in such cases and therefore the biggest challenge lies in keeping these patients fit and functional with optimum quality of life. The anxiety of parents is intensified due to the overall condition of the patient. This case report presents homoeopathic management of one such case. The patient was under treatment for almost a decade. Acute homoeopathic medicines efficiently managed acute haemorrhagic episodes. Constitutional medicine Bufo Rana was prescribed in the asymptomatic phase, which helped to reduce the frequency and intensity of bleeding and also helped to improve social quotient of the patient. The social quotient was assessed employing the Vineland Social Maturity Scale, and the result shows that the social quotient of the patient has improved from 8.3 to 41.66. The anxiety of parents also reduced, which was measured using the Family Interview for Stress and Coping in Mental Retardation Scale. The case analysis was done using a paired t-test. The p-value is less than 0.0001 and highly significant. The evaluation of the homoeopathic treatment was done using modified Naranjo criteria for homoeopathy. Homoeopathy medicines efficiently managed the acute episodes of bleeding and also showed improvement in the intellectual disability.
Perinatal Outcomes in Women with Chronic Kidney Diseases
Authors: Zilli Marcus Vinicius Pinheiro , Borovac-Pinheiro Anderson , Costa Maria Laura , Surita Fernanda Garanhani 
Published: December 2022

Abstract
Objective To assess maternal and neonatal outcomes in women with chronic kidney disease (CKD) at a referral center for high-risk pregnancy.
Methods A retrospective cohort of pregnant women with CKD was followed at the Women's Hospital of Universidade Estadual de Campinas, Brazil, between 2012 and 2020. Variables related to disease etiology, treatment duration, sociodemographic variables, lifestyle, other associated diseases, obstetric history, and perinatal outcomes were assessed. The causes of CKD were grouped into 10 subgroups. Subsequently, we divided the sample according to gestational age at childbirth, as preterm and term births, comparing maternal and neonatal outcomes, and baseline characteristics as well as outcomes among such groups.
Results A total of 84 pregnancies were included, in 67 women with CKD. Among them, six pregnancies evolved to fetal death, five to miscarriage, and one was a twin pregnancy. We further analyzed 72 single pregnancies with live births; the mean gestational age at birth was 35 weeks and 3 days, with a mean birth weight of 2,444 g. Around half of the sample (51.39%) presented previous hypertension, and 27.7% developed preeclampsia. Among the preterm births, we observed a higher frequency of hypertensive syndromes, longer maternal intensive care unit (ICU) stay in the postpartum period, higher incidence of admission to the neonatal ICU, higher neonatal death, lower 5-minute Apgar score, and lower birth weight.
Conclusion This study demonstrates increased adverse outcomes among pregnancies complicated by CKD and expands the knowledge on obstetric care among such women in an attempt to reduce maternal risks and identify factors related to prematurity in this population.
Role of Homoeopathy in Managing Chronic Paronychia: A Pretest–Posttest Interventional Study
Authors: Choubey Gurudev , Nahar Laijun , Purkait Rajib , Banerjee Abhiram , Roja Varanasi 
Published: December 2022

Abstract
Background Chronic paronychia (CP), one of the commonest recalcitrant nail disorders, is a troublesome source of considerable discomfort to the patients, which negatively affects the quality of life (QoL) mainly of the housewives reporting in the Indian subcontinent.
Objective The aim of this study is to assess the utility of individualised homoeopathic treatment (IHT) in managing painful episodes with the improvement in QoL of CP patients.
Method A pretest–posttest clinical study was conducted on 40 patients with CP. The Numeric Rating Scale (NRS) and Dermatology Life Quality Index (DLQI) were the outcome measures, assessed at baseline and after 2 months of IHT. Modified Naranjo Criteria (MNC) evaluated the possible causal attribution of IHT.
Results There was a statistically significant reduction in pain NRS score (8.89 ± 0.84 vs 2.97 ± 1.17; 95% confidence interval [CI] = 5.44–6.39; p < 0.01) as well as DLQI score (19.35 ± 2.95 vs 3.59 ± 1.99; 95% CI = 15.06–16.45; p < 0.01) among 37 patients. The large effect size derived (4.17) clinically, substantiates the beneficial effects in managing the painful episodes of CP. The MNC scores (7–10) ascertained the likelihood of improvement due to IHT.
Conclusion IHT significantly reduced the pains due to CP and improved the QoL. Further studies are warranted with enhanced methodology.
Lichen Spinulosus: Successfully Treated with Individualised Homoeopathic Treatment – A Case Report
Authors: Dastagiri P. , Savera Kaushal Kumar 
Published: December 2022

AbstractLichen spinulosus (LS) is a rare skin disorder that belongs to the family of Follicular Keratotic disorder, primarily seen in children. Its prevalence is more in boys, rarely in adults. The aetiology of this condition is still indefinite, but genetic predominance was noted. The skin lesions are follicular hyperkeratotic papules grouped into large patches, mainly on the neck and buttocks, abdomen and the extensor surface of arms and legs. The individual lesions are flat to conical projections, 1 to 3 mm in diameter, which bears a hair-like horny spine, protruding approximately 1 to 2 mm above the surface, which are the characteristics of this disease. This case of an 8-year-old boy was reported in the outpatient department of our institute and diagnosed as LS. This case report aims to show the importance of individualised prescription based on the totality of symptoms (TOS) in homoeopathic treatment; even the name of the disease is not mentioned in the homoeopathic literature. From the constructed TOS and constitution of the patient, Calcarea Phosphoricum 200C medicine was prescribed, which improved this condition successfully without using any topicals.
Review on Ethics in Research – Homoeopathic Perspective
Authors: Sahoo Amulya Ratna , Damodaran Banupriya , Nayak Chaturbhuja , Prusty Umakanta , Ghosh Priyanka 
Published: December 2022

AbstractEthics is a moral principle that governs a system. Research ethics may be defined as doing what is morally and legally right in research. Despite dealing with human beings, homoeopathy research deals with human clinical, pre-clinical (drug proving) trials, preclinical animal studies, veterinary studies and plant studies that demand varied ethical strategies. The importance of ethics in medical research is mandated to avoid adverse events before, during and after the trials. Ethics in medical practice and medical research is based on Nuremberg's Code and Declaration of Helsinki. The two major guidelines in the homoeopathic medical research publications are Reporting data on Homeopathic treatments (RedHot): A supplement to Consolidated Standards for Reporting Trials (CONSORT) for clinical trials and Reporting Experiments in Homeopathic Basic Research (REHBaR). This article discusses the evolution of ethics in medical research, principles of ethics, components to be considered pre-trial, during and post-trial. The evolution of strategies based on the principles of ethics in medical research is correlated.
Information and Data Visualization Needs among Direct Care Nurses in the Intensive Care Unit
Authors: Lindroth Heidi L. , Pinevich Yuliya , Barwise Amelia K. , Fathma Sawsan , Diedrich Daniel , Pickering Brian W. , Herasevich Vitaly 
Published: December 2022

Abstract
Objectives Intensive care unit (ICU) direct care nurses spend 22% of their shift completing tasks within the electronic health record (EHR). Miscommunications and inefficiencies occur, particularly during patient hand-off, placing patient safety at risk. Redesigning how direct care nurses visualize and interact with patient information during hand-off is one opportunity to improve EHR use. A web-based survey was deployed to better understand the information and visualization needs at patient hand-off to inform redesign.
Methods A multicenter anonymous web-based survey of direct care ICU nurses was conducted (9–12/2021). Semi-structured interviews with stakeholders informed survey development. The primary outcome was identifying primary EHR data needs at patient hand-off for inclusion in future EHR visualization and interface development. Secondary outcomes included current use of the EHR at patient hand-off, EHR satisfaction, and visualization preferences. Frequencies, means, and medians were calculated for each data item then ranked in descending order to generate proportional quarters using SAS v9.4.
Results In total, 107 direct care ICU nurses completed the survey. The majority (46%, n = 49/107) use the EHR at patient hand-off to verify exchanged verbal information. Sixty-four percent (n = 68/107) indicated that current EHR visualization was insufficient. At the start of an ICU shift, primary EHR data needs included hemodynamics (mean 4.89 ± 0.37, 98%, n = 105), continuous IV medications (4.55 ± 0.73, 93%, n = 99), laboratory results (4.60 ± 0.56, 96%, n = 103), mechanical circulatory support devices (4.62 ± 0.72, 90%, n = 97), code status (4.40 ± 0.85, 59%, n = 108), and ventilation status (4.35 + 0.79, 51%, n = 108). Secondary outcomes included mean EHR satisfaction of 65 (0–100 scale, standard deviation = ± 21) and preferred future EHR user-interfaces to be organized by organ system (53%, n = 57/107) and visualized by tasks/schedule (61%, n = 65/107).
Conclusion We identified information and visualization needs of direct care ICU nurses. The study findings could serve as a baseline toward redesigning an EHR interface.
Pulmonary function and medication effect in mild-stage subjects with Parkinson's disease
Authors: Oliveira Renata Terra de , Santos Fabiana Maria dos , Ramos Alessandro Gomes , Seki Karla Luciana Magnani , Müller Paulo de Tarso , Christofoletti Gustavo 
Published: December 2022

Abstract
Background Parkinson's disease (PD) causes a series of movement disorders, many of them starting in the early stage.
Objective To analyze the pulmonary function of mild-stage subjects with PD and to investigate the effects of levodopa on it.
Methods We included 21 patients with idiopathic PD and 20 healthy control subjects. The participants were submitted to spirometry and impulse oscillometry assessments. The PD patients were evaluated during the “off” and “on” phases of their anti-PD medication, which was was converted to levodopa in an equivalent daily dose. A statistical analysis was performed with cross-sectional (PD patients “off” medication versus controls) and paired (PD patients “off” medication versus PD patients “on” medication) tests. The effect of levodopa was calculated with partial Eta-squared (η2
ρ). Significance was set at 5%.
Results The PD patients presented normal values in the impulse oscillometry. Regarding spirometry, the results indicated an incipient obstructive ventilatory disorder in the PD group – confirmed by patients' flow-volume curves. The PD patients received a daily dose of 354.7 ± 148.2 mg of levodopa. The paired analyses showed a small effect of anti-PD medication on pulmonary parameters (η2
ρ = 0.197 for spirometry and η2
ρ= 0.043 for impulse oscillometry).
Conclusion Patients with PD in the mild stage of the disease present pulmonary compliance and resistance compatible with normal parameters. The differences regarding the spirometric results indicate an incipient obstructive ventilatory disorder in patients with PD. Levodopa had small effect on pulmonary function in the mild stage of the disease.
A clinical evaluation of gelastic and dacrystic seizures: a multicenter study
Authors: Demir Aylin Bican , Öz Başak Yılmaz , Yıldız Mustafa Onur , Türk Bengi Gül , Tanrıverdi Taner , Bekar Ahmet , Yeni Naz , Bora İbrahim 
Published: December 2022

AbstractBackground Gelastic seizures are extremely rare, short-lasting, unprovoked, and uncontrollable laughing attacks. We conducted this retrospective evaluation to determine whether these symptoms, manifesting in different forms, such as cheerful laughter, laughing, smiling, and sobbing had any value in terms of etiology or localization.Methods A total of 31 patients who exhibited bouts of laughing or crying and who were under follow-up between 2000 and 2019 at tertiary epilepsy centers were included in the study. Laughing seizures were divided into three groups in terms of semiology (i.e., laughter with mirth, laughter without mirth, and smile). Dacrystic seizures were accompanied by some gelastic seizures and were divided into two groups in terms of semiology (i.e., weeping loudly [motor and voice-sobbing] and crying).Results Of the 27 patients with laughing seizures, 12 had seizures that manifested with smiling, 7 had seizures that manifested with laughing and mirth, and 8 had seizures that manifested with laughter without mirth. Dacrystic-gelastic seizures were observed in four patients, among whom 2 patients had crying and laughter without mirth and 2 patients had weeping loudly and laughter without mirth episodes.Conclusion Gelastic and dacrystic seizures often suggest hypothalamic hamartomas, in the literature. This rare ictal behavior can originate from different cortical locations and lesions of a different nature. However, we found that gelastic seizures with smiling were a more homogenous group with regard to location in the temporal lobe, which we aimed to show by evaluating the patients included in this study.