bluuebunny/crossref_metadata_2025_split huggingface dataset:
An investigation on fatigue, fracture resistance, and color properties of aesthetic CAD/CAM monolithic ceramics
Authors: Fouda Ahmed Mahmoud , Atta Osama , Özcan Mutlu , Stawarczyk Bogna , Glaum Robert , Bourauel Christoph 
Published: December 2022

Abstract
Objectives
To evaluate and compare fracture resistance, translucency, and color reproducibility, as well as the effect of aging on the fracture load and color stability of novel monolithic CAD/CAM ceramics.

Materials and methods
One hundred crowns of uniform thickness were milled from five ceramic blocks (n = 20): partially crystallized lithium disilicate (PLD) and fully crystallized lithium disilicate (FLD), lithium metasilicate (LMS), 4Y-TZP (SMZ), and 5Y-TZP (UMZ) monolithic zirconia. PLD crowns were glazed, LMS was fired, and FLD was polished. SMZ and UMZ crowns were sintered and polished. Crowns were adhesively cemented to epoxy dies. Half of the crowns (n = 10) were subjected to 1.200.000 load cycles with thermal cycling. Color space values L, a, b defined by the Commission Internationale de l´Eclairage (CIELAB) were measured before and after aging, and (∆E) was calculated. Both aged and non-aged specimens were loaded until fracture in a universal testing machine and the fracture load was recorded. X-ray diffraction (XRD) and scanning electron microscope (SEM) fractographic analysis were carried out on fractured fragments of representative samples. For translucency and color reproducibility, 50 rectangular-shaped specimens were fabricated and processed as described previously. Color values were measured over black and white backgrounds, and the translucency parameter (TP) was computed. Using the shade verification mode, (∆E) to shade A3 was calculated. Data were statistically analyzed using one-way and two-way ANOVA, and t-test.

Results
Aging did not affect fracture resistance significantly (p > 0.05). The highest mean fracture load was obtained for the SMZ and UMZ. A significant color change was observed after aging in all groups. The highest TP was noted for FLD. SMZ and UMZ had the best shade match.

Conclusions
Zirconia showed higher fracture resistance and color stability than lithium silicate ceramics. Lithium silicate ceramics were more translucent. The experimental FLD demonstrated high translucency.

Clinical relevance
Tested ceramics showed sufficient stability to withstand masticatory forces. Characterization of final restorations might be mandatory for better color match.
Lessons learned in animal acoustic cognition through comparisons with humans
Authors: Hoeschele Marisa , Wagner Bernhard , Mann Dan C. 
Published: December 2022

AbstractHumans are an interesting subject of study in comparative cognition. While humans have a lot of anecdotal and subjective knowledge about their own minds and behaviors, researchers tend not to study humans the way they study other species. Instead, comparisons between humans and other animals tend to be based on either assumptions about human behavior and cognition, or very different testing methods. Here we emphasize the importance of using insider knowledge about humans to form interesting research questions about animal cognition while simultaneously stepping back and treating humans like just another species as if one were an alien researcher. This perspective is extremely helpful to identify what aspects of cognitive processes may be interesting and relevant across the animal kingdom. Here we outline some examples of how this objective human-centric approach has helped us to move forward knowledge in several areas of animal acoustic cognition (rhythm, harmonicity, and vocal units). We describe how this approach works, what kind of benefits we obtain, and how it can be applied to other areas of animal cognition. While an objective human-centric approach is not useful when studying traits that do not occur in humans (e.g., magnetic spatial navigation), it can be extremely helpful when studying traits that are relevant to humans (e.g., communication). Overall, we hope to entice more people working in animal cognition to use a similar approach to maximize the benefits of being part of the animal kingdom while maintaining a detached and scientific perspective on the human species.
The implication of calf circumference and grip strength in osteoporosis and bone mineral density among hemodialysis patients
Authors: Ozawa Moe , Hirawa Nobuhito , Haze Tatsuya , Haruna Aiko , Kawano Rina , Komiya Shiro , Ohki Yuki , Suzuki Shota , Kobayashi Yusuke , Fujiwara Akira , Saka Sanae , Hanaoka Masaaki , Mitsuhashi Hiroshi , Yamaguchi Satoshi , Ohnishi Toshimasa , Tamura Kouichi 
Published: December 2022

Abstract
Background
Chronic kidney disease–mineral and bone disorder (CKD–MBD), nutritional status, and uremia management have been emphasized for bone management in hemodialysis patients. Nevertheless, valuable data on the importance of muscle mass in bone management are limited, including whether conventional management alone can prevent osteoporosis. Thus, the importance of muscle mass and strength, independent of the conventional management in osteoporosis prevention among hemodialysis patients, was evaluated.

Methods
Patients with a history of hemodialysis 6 months or longer were selected. We assessed the risk for osteoporosis associated with calf circumference or grip strength using multivariable adjustment for indices of CKD–MBD, nutrition, and dialysis adequacy. Moreover, the associations between bone mineral density (BMD), calf circumference, grip strength, and bone metabolic markers were also evaluated.

Results
A total of 136 patients were included. The odds ratios (95% confidence interval) for osteoporosis at the femoral neck were 1.25 (1.04–1.54, P < 0.05) and 1.08 (1.00–1.18, P < 0.05) per 1 cm shorter calf circumference or 1 kg weaker grip strength, respectively. Shorter calf circumference was significantly associated with a lower BMD at the femoral neck and lumbar spine (P < 0.001). Weaker grip strength was also associated with lower BMD at the femoral neck (P < 0.01). Calf circumference or grip strength was negatively correlated with bone metabolic marker values.

Conclusion
Shorter calf circumference or weaker grip strength was associated with osteoporosis risk and lower BMD among hemodialysis patients, independent of the conventional therapies.
Comparing three different Phaeodactylum tricornutum strains for the production of chrysolaminarin in flat panel airlift photobioreactors
Authors: Frick Konstantin , Yeh Yen-Cheng , Schmid-Staiger Ulrike , Tovar Günter E. M. 
Published: December 2022

AbstractIn recent years, various applications for algae-based ß-1,3-glucans have been postulated, including animal feed and human nutrition. Chrysolaminarin is a ß-1,3–1,6-glucan produced by diatoms such as Phaeodactylum tricornutum for energy storage. It is accumulated under nutrient-depleted cultivation conditions. In this study, the production of chrysolaminarin in artificially illuminated scalable flat panel airlift photobioreactors (FPA) was investigated by using P. tricornutum in a two-stage production process. In the growth stage primarily biomass is produced, and the subsequent nitrogen-depleted stage induces the accumulation of chrysolaminarin. Three P. tricornutum strains (SAG 1090-1a, SAG 1090-1b, SAG 1090–6) were cultured at laboratory scale in 6 L-FPA reactors under controlled light conditions to characterize the process and identify a production strain. The chrysolaminarin content of the algae strains was analysed and additionally their contents of eicosapentaenoic acid and fucoxanthin, both of which could be involved in a possible co-production. Strain SAG 1090-1b exhibited the highest biomass productivity and chrysolaminarin content (317 ± 9 mg gDW−1) after nitrogen depletion, and thus stood out as the most suitable for chrysolaminarin production in a two-stage process. A co-production of the three compounds is possible. However, during nitrogen depletion there occurred trade-offs between the compounds. As chrysolaminarin was produced, the amount of fucoxanthin in the culture stagnated or even decreased depending on the selected strain.
Pre exposure to enriched environment alleviates brain injury after ischemia-reperfusion by inhibiting p38MAPK/STAT1 pathway
Authors: Shen Xin-Ya , Han Yu , Gao Zhen-Kun , Han Ping-Ping , Bi Xia 
Published: December 2022

Abstract
Background
Stroke is one of the major diseases that endangers human health. It is widely reported that enriched environment (EE) can improve the neurological function in different brain injury models. Recently, relevant researches have indicated that MAPK pathway is closely related to the inflammatory response in nervous system related diseases. However, whether pre exposure to EE (EE pretreatment) has a preventive effect, and its mechanism are not clear. Therefore, this study aimed to determine the possible benefits and related mechanisms of EE in preventing brain injury after acute ischemia-reperfusion.

Methods
Adult Sprague Dawley rats were kept in enriched or standardized environments for 21 days. Then the middle cerebral artery of rats was occluded for one hour and 30 min, and then reperfusion was performed. Then their neurological deficit score was evaluated. Cerebral edema, along with ELISA and protein quantities of p38MAPK, JNK, ERK, IL-1β, TNF-α, and co-localization of Iba1 were assessed. Changes in neuroinflammation and apoptosis were also detected in the penumbra cortex.

Results
Our research showed that EE pretreatment significantly alleviated acute cerebral ischemia-reperfusion injury in rats. Including the reduction of brain edema and apoptosis, and the improvement of neurological scores. In addition, the protein level of p38MAPK was significantly down regulated in EE pretreatment group, and the downstream protein STAT1 had the same trend. In addition, immunofluorescence results showed that Iba1 in EE pretreatment group decreased, the ELISA results showed that the classical proinflammatory cytokines increased significantly, while anti-inflammatory cytokines in EE pretreatment group increased, and the same results were obtained by Western blot analysis.

Conclusion
On the whole, our research demonstrated that EE pretreatment can have a protective effect on the organism by inhibiting the p38 MAPK/STAT1 pathway. Thus, EE can be one of the most promising means of disease prevention. Secondly, p38MAPK/STAT1 pathway may be a latent target for the prevention of acute ischemic stroke.
Person effects in agreement with Icelandic low nominatives: An experimental investigation
Authors: Hartmann Jutta M. , Heycock Caroline 
Published: December 2022

AbstractThis paper investigates agreement—in particular person agreement—in two configurations in Icelandic where there are two potential controllers of agreement and where at least in some cases agreement is with the lower of the two (a “low nominative”). One case is theDative-Nominativeconstruction, where there is a dative subject and a lower nominative argument. The other is theSpecificational Copular Clause (SCC)construction, where there are two nominative arguments. A much-discussed aspect of agreement in the former case is that agreement in number with the low nominative is generally possible, but agreement in person is at best highly restricted, leading in some cases to ineffability. This person effect has been claimed to be ameliorated by syncretism in the agreement paradigm, but there is limited data available substantiating this effect, which is however crucial to deciding between two recent types of account. This paper reports on a pair of experimental rating studies on theDat-Nomand SCC configurations in Icelandic. We show that, taken together, the two sets of data provide evidence against the Person Licensing Condition and in favour of an account of theDat-Nomconstruction in terms of morphological conflict arising from double agreement, although we show that the ameliorating effect of morphological syncretism, while real, is limited. Further, we show that there is no evidence of double agreement in the copular clauses investigated. We argue that full agreement with the low nominative here arises if the first nominal can move out of the domain of agreement entirely. The possibility of agreement with the initial nominal we suggest indicates that nominatives, unlike datives, cause the search of the agreement probe to terminate.
An urban drought categorization framework and the vulnerability of a lowland city to groundwater urban droughts
Authors: Machairas Ilias , van de Ven Frans H. M. 
Published: December 2022

AbstractDue to climate change, droughts will intensify in large parts of the world. Drought and its impacts on nature and agriculture have been studied thoroughly, but its effects on the urban environment is rather unexplored. But also the built environment is susceptible to droughts and estimation of its vulnerability is the first step to its protection. This article is focusing on assessing the vulnerability of a city to groundwater drought, using parts of the lowland city of Leiden, the Netherlands, as a case study. Using a new urban drought categorization framework, groundwater drought is separated from soil moisture drought, open water drought and water supply drought, as each has its own impacts. Vulnerability was estimated as the aggregation of drought exposure and damage sensitivity. Drought deficit and duration were used as exposure indicators. Both a Fixed and Variable threshold method was used to quantify these indicators. To quantify drought vulnerability weights were assessed for selected exposure and damage sensitivity indicators using an Analytical Hierarchy Process (AHP) with a small number of experts. Based on these weights the spatial variation in vulnerability for groundwater drought follows damage sensitivity patterns—rather than exposure ones. And, out of all damage sensitivity indicators used, ‘land use', ‘low income' and ‘monuments’ contributed the most to the spatial variation in vulnerability. Due to the fact that the number of drought experts’ opinions in the AHP was limited these vulnerability results however remain uncertain. The proposed methodology however allows water managers to determine vulnerability of urbanized areas to groundwater drought, identify highly vulnerable areas and focus their mitigating actions.
On resonances and transverse and longitudinal oscillations in a hoisting system due to boundary excitations
Authors: Wang Jing , van Horssen Wim T. 
Published: December 2022

AbstractIn this paper, we study transverse and longitudinal oscillations and resonances in a hoisting system induced by boundary disturbances. The dynamics can be described by an initial-boundary value problem for a coupled system of nonlinear wave equations on a slowly time-varying spatial domain. It will be shown how the boundary excitations and the nonlinear terms influence transverse and longitudinal vibrations of the system. Firstly, due to the slow variation of the cable length, a singular perturbation problem arises. By using an interior layer analysis, many resonance manifolds are detected. Secondly, it will be shown that resonances in the system are caused not only by boundary disturbances but also by nonlinear interactions. Based on these observations, a three-timescales perturbation method is used to approximate the solution of the initial-boundary value problem analytically. It turns out that for special frequencies in the boundary excitations and for certain parameter values of the longitudinal stiffness and the conveyance mass, many oscillation modes jump up from small to large amplitudes in the transverse and longitudinal directions. Finally, numerical simulations are presented to verify the obtained analytical results.
Gay and Straight Men Prefer Masculine-Presenting Gay Men for a High-Status Role: Evidence From an Ecologically Valid Experiment
Authors: Gerrard Benjamin , Morandini James , Dar-Nimrod Ilan 
Published: December 2022

AbstractThere is increased acceptance of gay men in most Western societies. Nevertheless, evidence suggests that feminine-presenting gay men are still disadvantaged compared to gay men who present in a more traditionally masculine way. Though gay men themselves may be complicit in perpetuating this bias, studies that demonstrate this possibility are scant. Whereas most studies on perceptions of feminine-presenting gay men have manipulated gender nonconformity via written descriptions, research suggests that behavioural cues such as voice and body-language can mitigate or exacerbate prejudice toward a stereotyped individual. In the current study, audio-visual stimuli were created to investigate how masculine versus feminine behaviour would impact status endowment from other gay and heterosexual men. In total, 256 men (Mage = 42.73, SD = 14.48: half gay; half heterosexual) cast, from a selection of six video-taped candidates, one gay man to play a lead role in a purported ad for a tourism campaign. In the videos, the actors delivered a script related to the tourism campaign in a manner where their voice and body-language was manipulated to come across as either masculine or feminine-presenting. Findings indicated that gay and heterosexual participants showed a significant preference for the masculine videoclips. For heterosexual men, the preference for masculine-presenting actors was predicted by greater anti-gay sentiment, whereas internalised anti-gay prejudice did not predict a preference for masculine-presentation among gay men. Implications of the findings for discourse and education on intraminority prejudice and suggestions for future research are offered.
Revisiting the gravity laws of inter-city mobility in megacity regions
Authors: Zhao Pengjun , Hu Haoyu , Zeng Liangen , Chen Jun , Ye Xinyue 
Published: December 2022

AbstractInter-city mobility is one of the most important issues in the UN Sustainable Development Goals, as it is essential to access the regional labour market, goods and services, and to constrain the spread of infectious diseases. Although the gravity model has been proved to be an effective model to describe mobility among settlements, knowledge is still insufficient in regions where dozens of megacities interact closely and over 100 million people reside. In addition, the existing knowledge is limited to overall population mobility, while the difference in inter-city travel with different purposes is unexplored on such a large geographic scale. We revisited the gravity laws of inter-city mobility using the 2.12 billion trip chains recorded by 40.48 million mobile phone users’ trajectories in the Jing-Jin-Ji Region, which contains China’s capital Beijing. Firstly, unlike previous studies, we found that non-commuting rather than commuting is the dominant type of inter-city mobility (89.3%). Non-commuting travellers have a travel distance 42.3% longer than commuting travellers. Secondly, we developed more accurate gravity models for the spatial distribution of inter-city commuting and non-commuting travel. We also found that inter-city mobility has a hierarchical structure, as the distribution of inter-city travel volume follows Zipf’s law. In particular, the hierarchy of non-commuting travel volume among the cities is more in line with an ideal Zipf distribution than commuting travel. Our findings contribute to new knowledge on basic inter-city mobility laws, and they have significant applications for regional policies on human mobility.
Modelling crop yield and harvest index: the role of carbon assimilation and allocation parameters
Authors: Camargo-Alvarez Hector , Elliott Robert J. R. , Olin Stefan , Wang Xuhui , Wang Chenzhi , Ray Deepak K. , Pugh Thomas A. M. 
Published: December 2022

AbstractCrop yield improvement during the last decades has relied on increasing the ratio of the economic organ to the total aboveground biomass, known as the harvest index (HI). In most crop models, HI is set as a parameter; this empirical approach does not consider that HI not only depends on plant genotype, but is also affected by the environment. An alternative is to simulate allocation mechanistically, as in the LPJ-GUESS crop model, which simulates HI based on daily growing conditions and the crop development stage. Simulated HI is critical for agricultural research due to its economic importance, but it also can validate the robust representation of production processes. However, there is a challenge to constrain parameter values globally for the allocation processes. Therefore, this paper aims to evaluate the sensitivity of yield and HI of wheat and maize simulated with LPJ-GUESS to eight production allocation-related parameters and identify the most suitable parameter values for global simulations. The nitrogen demand reduction after anthesis, the minimum leaf carbon to nitrogen ratio (C:N) and the range of leaf C:N strongly affected carbon assimilation and yield, while the retranslocation of labile stem carbon to grains and the retranslocation rate of nitrogen and carbon from vegetative organs to grains after anthesis mainly influenced HI. A global database of observed HI for both crops was compiled for reference to constrain simulations before calibrating parameters for yield against reference data. Two high- and low-yielding maize cultivars emerged from the calibration, whilst spring and winter cultivars were found appropriate for wheat. The calibrated version of LPJ-GUESS improved the simulation of yield and HI at the global scale for both crops, providing a basis for future studies exploring crop production under different climate and management scenarios.
Pros and Cons of Biochar to Soil Potentially Toxic Element Mobilization and Phytoavailability: Environmental Implications
Authors: Shaheen Sabry M. , Mosa Ahmed , Natasha  , Arockiam Jeyasundar Parimala Gnana Soundari , Hassan Noha E. E. , Yang Xing , Antoniadis Vasileios , Li Ronghua , Wang Jianxu , Zhang Tao , Niazi Nabeel Khan , Shahid Muhammad , Sharma Gaurav , Alessi Daniel S. , Vithanage Meththika , Hseu Zeng-Yei , Sarmah Ajit K. , Sarkar Binoy , Zhang Zengqiang , Hou Deyi , Gao Bin , Wang Hailong , Bolan Nanthi , Rinklebe Jörg 
Published: December 2022

AbstractWhile the potential of biochar (BC) to immobilize potentially toxic elements (PTEs) in contaminated soils has been studied and reviewed, no review has focused on the potential use of BC for enhancing the phytoremediation efficacy of PTE-contaminated soils. Consequently, the overarching purpose in this study is to critically review the effects of BC on the mobilization, phytoextraction, phytostabilization, and bioremediation of PTEs in contaminated soils. Potential mechanisms of the interactions between BC and PTEs in soils are also reviewed in detail. We discuss the promises and challenges of various approaches, including potential environmental implications, of BC application to PTE-contaminated soils. The properties of BC (e.g., surface functional groups, mineral content, ionic content, and π-electrons) govern its impact on the (im)mobilization of PTEs, which is complex and highly element-specific. This review demonstrates the contrary effects of BC on PTE mobilization and highlights possible opportunities for using BC as a mobilizing agent for enhancing phytoremediation of PTEs-contaminated soils.
Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor
Authors: Achternbosch Moritz , Zibula Lukas , Schmidt Annika , Krieger Waldemar , Kockmann Norbert , Strohmann Carsten 
Published: December 2022

AbstractOrganolithium compounds have been used successfully in flow chemistry since the recent past. Most of the studies dealt with the use in halogen-lithium exchanges. So far, however, there has been a lack of use in substitution reactions. The use of flow microreactors makes the highly reactive organolithium compounds more controllable and thus creates new synthetic possibilities.