bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ukrainian Orthodox Church Facing the Challenge of War (February – early June 2022)
Authors: Bureha Volodymyr 
Published: January 2025

The article is dedicated to the processes in the Ukrainian Orthodox Church (UOC) during the first three months of the escalation of the Russian-Ukrainian war. The author reconstructs the key events of church life over the course of February-May 2022 and shows that the Primate of the UOC consistently took a patriotic position, condemning Russian aggression from the first day of the escalation. The Church launched a wide range of humanitarian activities aimed at helping refugees and internally displaced persons and regularly provided assistance to the Armed Forces of Ukraine. To the contrary, the Moscow Patriarch Kirill unequivocally sided with the aggressor, which caused mass indignation among the parish clergy of the UOC and led to a movement calling against commemorating Patriarch Kirill during the service, which eventually developed into calls for the complete separation of the UOC from the Moscow Patriarchate. Consequentially, the most determined part of the clergy (more than 430 people) appealed to the heads of all the autocephalous Churches of the world with a call to bring Patriarch Kirill to the church court. The beginning of the war also caused a noticeable aggravation of state-church relations. Local authorities began to make decisions on banning the activity of UOC communities. An assembly of bishops, clergy, and laity was called by the Holy Synod of the UOC on May 27 in Kyiv, which grew into the UOC Council, which made fundamental changes to the UOC Statute and severed the connection of the UOC with the Moscow Patriarchate. While this constitutes a serious breakthrough for the UOC,, the author concludes that the status of the Ukrainian Orthodox Church can only be fully resolved only after the end of the war.
Hydrochemical Assessment of Water Quality and Risks Related to the Use of Groundwater Resources in the Urban Area of Niamey and Nearby Rural Areas in the Regions of Dosso and Tillabery in Niger
Authors: Mohamed MOUNKAILA , Zeinabou MAHAMADOU , Abdoulatif ABASS SALEY , Moussa RABILOU SOULEY , Maman INOUSSA Maarouhi , Salifou SOUMANA 
Published: January 2025

Groundwater continues to be useful as the main source of drinking water in semi-arid and arid regions of sub-Saharan Africa. The main goal of this work is to assess the health risks associated to the consumption of borehole water in urban and peri-urban areas of Niamey in Niger. Hydrochemical analyses were carried out from water samples of 16 boreholes using standard methods (AFNOR). The parameter measured are pH, Electric conductivity (EC), HCO3-, NO3-, NO2-, Cl-, SO42-, F-, Na+, K+, Ca2+, Mg2+, Fe2+ and Mn2+. 80% of the samples are very risky for the populations. About 56% of boreholes have a nitrate concentration < 30 mg/L and 44% of samples have more than 50 mg/L corresponding the limit standard set by the WHO. High nitrite contents (NO2-) were determined from the same borehole water samples and contain more than 10 mg/L, and are considered unfit. Main causes are the lack of good urban wastes managements, and the uncontrolled use fertilizers in the agricultural sectors. The sites containing between 2 and 3 mg/L of Fe2+ are located in areas of lateritic soils. About 12% of samples contain Mn2+ above the WHO standard (0.4 mg/L). This study of few boreholes from Niamey and its close rural areas demonstrates that nitrate, nitrite and manganese contents may cause major risks, in particular gastric, cardiovascular, carcinogenic and neurological diseases. With the growing population and urbanization, the lack of sanitation and of good management of urban waste, monitoring of groundwater quality is urgently need to preserve human health. Regular, rapid and less costly monitoring of the pH and electrical conductivity of urban borehole waters can help to prevent the risk of poisoning by nitrate, nitrite and by heavy metals such as manganese.
Super‐priority lien challenged for its state constitutionality in the United States of America
Authors: Nishiura Sadatsugu 
Published: July 2023

AbstractThis note focuses on super‐priority liens (SPLs), which allow homeowner associations to foreclose a property over its mortgage. Twenty‐two states have so far implemented such liens, hoping to balance the interests of mortgage creditors and homeowner associations. The state of Nevada has been facing more challenges from both mortgage creditors and homeowner associations regarding the constitutionality of non‐judicial foreclosure than other states. This paper summaries the cases since 2000 and discusses the three major decisions that the Supreme Court of Nevada made involving SPLs' non‐judicial constitutionality, tender‐extinguishing SPLs, and federal creditors' role in SPLs.
Predictive factors and diagnostic significance of CT findings for anastomotic leak after gastric cancer surgery: A retrospective analysis
Authors: Sah Birendra Kumar , Zhang Yang , Li Jian , Li Chen , Zhang Huan , Yan Min , Zhu Zheng Gang 
Published: July 2023

AbstractBackgroundAnastomotic leak following radical gastrectomy poses a significant risk to patients. Despite previous studies, effective methods for diagnosing anastomotic leaks after gastric cancer surgery remain elusive. In this study, we aimed to assess the overall burden of anastomotic leaks and investigate diagnostic factors, particularly radiological signs on postoperative computed tomography (CT), that may facilitate early detection.MethodsWe included a total of 70 gastric cancer patients who underwent curative gastrectomy and underwent CT examination post‐surgery. Among them, 35 patients with anastomotic leak were matched with 35 patients without anastomotic leak. We compared the rates of various types of postoperative complications between the two groups and conducted univariate and multivariate analyses to identify predictive variables for postoperative diagnosis.ResultsPatients with anastomotic leaks experienced significantly longer postoperative hospital stays and higher overall expenditures (p < 0.001). Logistic regression analysis revealed that extraluminal gas at the anastomosis site, fever (T ≥ 38.5°C), and neutrophilia (NE ≥ 78%) on postoperative days 4–7 were independent diagnostic factors for anastomotic leaks (p < 0.05).ConclusionsThe diagnostic factors identified in this study offer valuable insights into early detection of anastomotic leaks. We recommend early CT examination for patients exhibiting consistent fever and neutrophilia between postoperative days 4 and 7 following gastric cancer surgery.
A comprehensive study of skeletal muscle imaging in FHL1‐related reducing body myopathy
Authors: Mohassel Payam , Yun Pomi , Syeda Safoora , Batra Abhinandan , Bradley Andrew J. , Donkervoort Sandra , Monges Soledad , Cohen Julie S. , Leung Doris G. , Munell Francina , Ortez Carlos , Sánchez‐Montáñez Angel , Karachunski Peter , Brandsema John , Medne Livija , Chaudhry Vinay , Tasca Giorgio , Foley A. Reghan , Udd Bjarne , Arai Andrew E. , Walter Glenn A. , Bönnemann Carsten G. 
Published: July 2023

AbstractObjectiveFHL1‐related reducing body myopathy is an ultra‐rare, X‐linked dominant myopathy. In this cross‐sectional study, we characterize skeletal muscle ultrasound, muscle MRI, and cardiac MRI findings in FHL1‐related reducing body myopathy patients.MethodsSeventeen patients (11 male, mean age 35.4, range 12–76 years) from nine independent families with FHL1‐related reducing body myopathy underwent clinical evaluation, muscle ultrasound (n = 11/17), and lower extremity muscle MRI (n = 14/17), including Dixon MRI (n = 6/17). Muscle ultrasound echogenicity was graded using a modified Heckmatt scale. T1 and STIR axial images of the lower extremity muscles were evaluated for pattern and distribution of abnormalities. Quantitative analysis of intramuscular fat fraction was performed using the Dixon MRI images. Cardiac studies included electrocardiogram (n = 15/17), echocardiogram (n = 17/17), and cardiac MRI (n = 6/17). Cardiac muscle function, T1 maps, T2‐weighted black blood images, and late gadolinium enhancement patterns were analyzed.ResultsMuscle ultrasound showed a distinct pattern of increased echointensity in skeletal muscles with a nonuniform, multifocal, and “geographical” distribution, selectively involving the deeper fascicles of muscles such as biceps and tibialis anterior. Lower extremity muscle MRI showed relative sparing of gluteus maximus, rectus femoris, gracilis, and lateral gastrocnemius muscles and an asymmetric and multifocal, “geographical” pattern of T1 hyperintensity within affected muscles. Cardiac studies revealed mild and nonspecific abnormalities on electrocardiogram and echocardiogram with unremarkable cardiac MRI studies.InterpretationSkeletal muscle ultrasound and muscle MRI reflect the multifocal aggregate formation in muscle in FHL1‐related reducing body myopathy and are practical and informative tools that can aid in diagnosis and monitoring of disease progression.
Bioconjugation in Materials Science
Authors: Bednarek Christin , Schepers Ute , Thomas Franziska , Bräse Stefan 
Published: July 2023

AbstractWith the advent of bioconjugation chemistry in the last two decades, highlighted by the Nobel Prize 2022, the quest for possible novel applications has been greatly intensified, broadening the prospects of these mostly simple, specific, and high‐yield reactions. The advancement of bioconjugation methods is anticipated to expand the scope of bioinstructive and bioadaptive materials science in the future. This perspective article will discuss the reactions developed in this research area over the last 10 years for coupling various biological entities such as polysaccharides, oligonucleotides, peptides, and proteins. Building on this, the impact of bioconjugation reactions in materials science and 3D printing, including their challenges and requirements is shown. Established procedures for modifying molecular structures such as Covalent and Metal Organic Frameworks (COF/MOF) or hybrid materials for biomedical applications and the scope for future research and optimization will be presented.
Biomanufacturing of 3D Tissue Constructs in Microgravity and their Applications in Human Pathophysiological Studies
Authors: Ren Zhanping , Harriot Anicca D. , Mair Devin B. , Chung Michael K. , Lee Peter H. U. , Kim Deok‐Ho 
Published: July 2023

AbstractThe growing interest in bioengineering in‐vivo‐like 3D functional tissues has led to novel approaches to the biomanufacturing process as well as expanded applications for these unique tissue constructs. Microgravity, as seen in spaceflight, is a unique environment that may be beneficial to the tissue‐engineering process but cannot be completely replicated on Earth. Additionally, the expense and practical challenges of conducting human and animal research in space make bioengineered microphysiological systems an attractive research model. In this review, published research that exploits real and simulated microgravity to improve the biomanufacturing of a wide range of tissue types as well as those studies that use microphysiological systems, such as organ/tissue chips and multicellular organoids, for modeling human diseases in space are summarized. This review discusses real and simulated microgravity platforms and applications in tissue‐engineered microphysiological systems across three topics: 1) application of microgravity to improve the biomanufacturing of tissue constructs, 2) use of tissue constructs fabricated in microgravity as models for human diseases on Earth, and 3) investigating the effects of microgravity on human tissues using biofabricated in vitro models. These current achievements represent important progress in understanding the physiological effects of microgravity and exploiting their advantages for tissue biomanufacturing.
Global Literature Analysis of Organoid and Organ‐on‐Chip Research
Authors: Shoji Jun‐ya , Davis Richard P. , Mummery Christine L. , Krauss Stefan 
Published: July 2023

AbstractOrganoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical, physiological, or pathological states of tissues and organs. These technologies are widely regarded by academia, the pharmacological industry and regulators as key biomedical developments. To map advances in this emerging field, a literature analysis of 16,000 article metadata based on a quality‐controlled text‐mining algorithm is performed. The analysis covers titles, keywords, and abstracts of categorized academic publications in the literature and preprint databases published after 2010. The algorithm identifies and tracks 149 and 107 organs or organ substructures modeled as organoids and organ‐on‐chip, respectively, stem cell sources, as well as 130 diseases, and 16 groups of organisms other than human and mouse in which organoid/organ‐on‐chip technology is applied. The analysis illustrates changing diversity and focus in organoid/organ‐on‐chip research and captures its geographical distribution. The downloadable dataset provided is a robust framework for researchers to interrogate with their own questions.
Long Lifetime Delayed Fluorescent Materials with Water and Temperature Tolerability Based on Charge Separation States
Authors: Lu Peng , Zhou Mengdie , Gu Danyu , Yuan Yongjie , Yu Yan , Zhang Hailiang 
Published: July 2023

AbstractLong lifetime delayed fluorescent materials have great potential applications in bioimaging, anti‐counterfeiting encryption, lighting, and other fields. However, the preparation of functionalized long lifetime fluorescent materials with simple chemical structure and tunable luminescent behavior still poses significant challenges. In this article, a simple and effective method to prepare a series of long lifetime delayed fluorescent copolymers with temperature and humidity tolerance is presented. This method involves the copolymerization of 2‐bromo‐5‐hydroxybenzaldehyde derivative monomer (M1), which contains electron‐withdrawing groups, with naphthalimide derivative fluorescent monomer (M2), which contains electron‐donating groups. The results demonstrate that long‐range charge transfer occurs between the two components in copolymers, forming charge‐separated states that emit long lifetime delayed fluorescence after exciton recombination. The delayed luminescent behavior of the copolymer is directly influenced by the content of the M2 component. The maximum delayed fluorescence lifetime can reach 13.7 ms, and the fluorescence quantum yield is 39%. Interestingly, the polymer film of P3 can emit a maximum afterglow of 1.00 s after photoactivation. Even after being immersed in water for 49 days, the afterglow remains unchanged. Besides, the afterglow of P3 can exist for ≈0.43 s at 323 K. Even at 373 K, the afterglow for 0.2 s can still be observed.
High‐Capacity Sub‐Nano Divalent Silicon from Biosilicification
Authors: Liu Zi'ang , Wang Xuanpeng , Hu Jingwen , Meng Jiashen , Niu Chaojiang , Liu Fang , Cui Lianmeng , Yu Ruohan , Mai Liqiang 
Published: July 2023

AbstractIn terms of high capacity and reliable safety, low‐valent silicon‐based composites with small grain sizes are practicable anode materials for lithium‐ion batteries. However, robust tetravalent silicon precursors make the synthesis hard to be green. Using biosilicification in water hyacinth (Eichhornia crassipes), it is found to be a superior natural precursor of low‐valent silicon. The biogenic sub‐nano (0.5 nm) siliceous dots composite (EC‐SiOC) shows a reversible conversion mechanism between Si─O and C─O bonds, unlike previous lithium storage mechanisms associated with alloying reactions. Due to the homogeneous biogenic structure facilitating the solid‐phase reaction, the normalized energy consumption of pyrolytic EC‐SiOC is about 80% lower than the carbothermic reduction of silica, similar to molten salt electrolysis. Statistically, the sampling survey of EC‐SiOC from different regions shows a high average capacity of 749.9 mAh g−1under a current density of 100 mA g−1. This study reveals the great potential of biomass precursors for synthesizing Si─O─C materials.
Updates in chronic graft‐versus‐host disease management
Authors: Malard Florent , Mohty Mohamad 
Published: July 2023

AbstractChronic graft‐versus‐host disease (cGvHD) remains the most important long‐term complication of allogeneic hematopoietic cell transplantation (allo‐HCT), but the field has seen significant changes in the last decade. Remarkable advances in the understanding of the biological pathways of cGvHD, lead to the development of targeted therapy with novel drugs thereby minimizing the exposure to harmful corticosteroids, preserving function and mobility, preventing disability, and improving quality of life (QoL) and overall survival (OS). Steroid‐refractory cGvHD management has recently experienced significant improvement since ibrutinib and ruxolitinib were approved for patients that failed at least one line of treatment and belumosudil for patients that failed two lines. These recently approved drugs will be discussed in this review, along with perspectives regarding cGVHD management and additional promising drug in development.
Pneumoconiosis incidence and prevalence among US Medicare beneficiaries, 1999–2019
Authors: Kurth Laura , Casey Megan L. , Mazurek Jacek M. , Blackley David J. 
Published: July 2023

AbstractBackgroundPneumoconiosis is a group of occupational lung diseases caused by dust and fiber exposure. This study analyzes Medicare claims to estimate the burden of pneumoconiosis among fee‐for‐service (FFS; Medicare Parts A and B) Medicare beneficiaries during 1999–2019 in the United States.MethodsClaim and enrollment information from 81 million continuously enrolled FFS Medicare beneficiaries were analyzed. Beneficiaries with any pneumoconiosis and cause‐specific pneumoconiosis (e.g., asbestosis, silicosis) were identified using three case definitions (broad, intermediate, and narrow) with varying diagnostic criteria based on claim International Classification of Diseases, Clinical Modification (ICD‐CM) diagnosis codes and Healthcare Common Procedure Coding System codes. Results are presented as ranges of values for the three case definitions.ResultsThe 21‐year prevalence range for any pneumoconiosis was 345,383–677,361 (412–833 per 100,000 beneficiaries) using the three case definitions. The highest prevalence was among those ≥75 years of age, males, Whites, and North American Natives. Most claims (70.0%–72.5%) included an ICD‐CM diagnosis code for asbestosis. The broad pneumoconiosis prevalence rate increased significantly (p < 0.001) during 2002–2009 by 3%–10% annually and declined significantly by 3%–5% annually starting in 2009. The average annual broad incidence rate declined significantly by 7% annually during 2009–2019.ConclusionsDespite the decline in rate for any pneumoconiosis among Medicare beneficiaries, which is primarily attributed to a decline in asbestosis, pneumoconiosis is prevalent among FFS Medicare beneficiaries.
Electrophilic Sulfenylation/Cyclization of N‐Aryl and N‐Benzyl Propynamides: Synthesis of Sulfenyl Quinolinones and 3H‐Benzo[c]azepin‐3‐ones
Authors: Yang Ping , Tang Meizhong , Liu Yankui , Zhang Weijun , Wang Ye‐Xin , Wang Jia , Xie Lan‐Gui 
Published: July 2023

AbstractQuinolinones and benzo[c]azepinones are important cores in biologically active molecules. We report the cyclization of N‐substituted propynamides, initiated by readily available electrophilic sulfenylating agent, enabling the synthesis of quinolinones and benzo[c]azepinones in exceedingly simple conditions. The approach shows excellent generality to the substrates and tolerability of functional groups. The anti‐inflammatory effect of the newly synthesized 3‐sulfenyl quinolinone and the 4‐sulfenyl benzo[c]azepinone products are tested, and two compounds are confirmed to have inhibitive effect on TNF‐α expression.
Feeling a bit peckish: Seasonal and opportunistic insectivory for wild gorillas
Authors: Auger Claire , Cipolletta Chloé , Todd Angelique , Fuh Terence , Sotto‐Mayor Andrea , Pouydebat Emmanuelle , Masi Shelly 
Published: July 2023

AbstractObjectivesInsectivory likely contributed to survival of early humans in diverse conditions and influenced human cognitive evolution through the need to develop harvesting tools. In living primates, insectivory is a widespread behavior and frequently seasonal, although previous studies do not always agree on reasons behind this. Since western gorillas (Gorilla gorilla) diet is largely affected by seasonal variation in fruit availability, we aimed to test three non‐mutually exclusive hypotheses (habitat use, frugivory and rainfall) to explain seasonality in termite feeding across age/sex classes in three habituated groups (Nindividuals = 27) in Central Africa.Materials and MethodsWe used 4 years of ranging, scan and continuous focal sampling records of gorillas (Nranging days = 883, Nscans = 12,384; Nhours = 891) in addition to 116 transects recording vegetation and termite mound distribution.ResultsDepending on the age/sex classes, we found support for all three hypotheses. Time spent in termite‐rich vegetation positively impacted termite consumption in all age/sex classes, but subadults. Lengthier travels increased termite feeding in females but decreased it in subadults. Frugivory decreased termite consumption in adults. Daily rainfall had a positive effect on termite feeding and foraging in silverbacks and juveniles, but a negative effect in subadults. For females, rainfall had a positive effect on termite feeding, but a negative effect for termite foraging.DiscussionIn great apes, seasonal insectivory seems to be multifactorial and primarily opportunistic with important differences among age/sex classes. While insectivory has potentials to be traditional, it likely played a crucial role during primate evolution (including ours), allowing diet flexibility in changing environments.
Reactivity Umpolung of Tertiary Amide Enabled by Catalytic Reductive Stannylation
Authors: Shi Qiu , Liu Wenbo H. 
Published: July 2023

AbstractReactivity umpolung is an important concept in organic chemistry. Established reactivity umpolung mainly focuses on the aldehyde and umpolung of amide carbonyl group is not known. In this report, we describe a process to obtain the umpolung reactivity of tertiary amide. This process hinges on the efficient reductive stannylation catalyzed by Ir/silane and facile Sn−Li exchange. By leveraging this umpolung reactivity, drug Fluoxetine was derivatized to 12 different analogues via reacting with various electrophiles and four biologically active molecules were prepared concisely. This unlocked umpolung reactivity of tertiary amide is expected to find applications to synthesize complex amines from amides.
Preparation and characterization of red mud/liquid silicon rubber with good thermal‐stability and processability
Authors: Wang Dingsong , Qin Jingjing , Liu Jiaming , Wu Mengqin , Fu Lifu , Liu Xiaohong , Shi Min , Liang Liyan , Dong Yonglu 
Published: July 2023

AbstractAs reported herein, a novel addition‐type liquid silicone rubber (LSR)/red mud (RM) composite has been synthesized. Triethoxyvinylsilane (KH151) was used as a surface modification agent to treat RM and form hydrophobic surfaces. The optimal formulation of the composite was determined by the mechanical properties of the LSR that were prepared at different crosslinker and filler contents. The reinforcement mechanism of modified RM on LSR was revealed by combining Fourier transform infrared (FTIR) spectroscopy, x‐ray photoelectron spectroscopy and mechanical property tests. Thermal degradation behavior of RM/LSR at elevated temperature was investigated by the thermogravimetric analysis (TG), TG‐FTIR and alteration of mechanical properties after thermal aging. The results of the experiment indicate that modified RM increased the tensile strength and Young's modulus of LSR dramatically and provides superior thermal stability to the LSR. With 100 phr RM added, the tensile strength of RM/LSR composite was almost 12 times greater than that of pure LSR, and pure LSR degrades completely after aging at 300°C for 24 h while RM/LSR retains its mechanical properties.