bluuebunny/crossref_metadata_2025_split huggingface dataset:
In Vitro Study of the Interaction between Ochratoxin A and Human Serum Albumin by Spectroscopic and Molecular Docking Methods
Authors: Vakili Sajedeh , Baher Elham , Vaezi Zahra , Mianabadi Manijeh , Tilami Salma Ehsani 
Published: September 2023

AbstractOchratoxin A (OA) is a mycotoxin that has a potential risk to human health due to its nephrotoxic, immunotoxic and carcinogenic effects. For these reasons the interaction of ochratoxin A with human serum albumin (HSA) was investigated in physiological media by various techniques such as UV‐Vis, fluorescence (FL), circular dichroism (CD), attenuated total reflection (ATR), differential scanning calorimetry (DSC), atomic force microscopy (AFM) and molecular docking study via Auto Dock‐vina software. The fluorescence intensity of tryptophan in HSA was strongly quenched in the present of OA and the quenching constants and binding constant were valued 108 M−1 and 1.04 M−1, respectively. The CD spectra showed alteration in the secondary structure of HSA in the presence of ochratoxin by reducing the regular alpha helical structure and increasing the beta‐sheet structure. By increasing the concentration of OA to 1.25 μM, the intensity of absorption spectrum at 282 nm was increased, indicating the strong interaction of OA and HSA. The enthalpies of these molecular interaction calculated from DSC analysis indicate OA interaction with HAS is exothermic. The docking calculations showed that the amino acids of Lys190, ASP187, LYS519, ARG186 and ARG428 were interacted with OA by hydrogen bonding.
Unveiling LiTFSI Precipitation as a Key Factor in Solid Electrolyte Interphase Formation in Li‐Based Water‐in‐Salt Electrolytes
Authors: Jommongkol Rossukon , Deebansok Siraprapha , Deng Jie , Zhu Yachao , Bouchal Roza , Fontaine Olivier 
Published: September 2023

AbstractA water‐in‐salt electrolyte is a highly concentrated aqueous solution (i.e., 21 mol LiTFSI in 1 kg H2O) that reduces the number of water molecules surrounding salt ions, thereby decreasing the water activity responsible for decomposition. This electrolyte widens the electrochemical stability window via the formation of a solid electrolyte interphase (SEI) at the electrode surface. However, using high concentration electrolytes in Li‐ion battery technology to enhance energy density and increase cycling stability remains challenging. A parasitic reaction, called the hydrogen evolution reaction, occurs when the reaction operates at a lower voltage. It is demonstrated here that a micrometric white layer is indeed a component of the SEI layer, not just on the nanoscale, through the utilization of an operando high‐resolution optical microscope. The results indicate that LiTFSI precipitation is the primary species present in the SEI layer. Furthermore, the passivation layer is found to be dynamic since it dissolves back into the electrolyte during open circuit voltage.
Thermal Emission Manipulation Enabled by Nano‐Kirigami Structures
Authors: Zhao Yinghao , Liang Qinghua , Li Sufan , Chen Yingying , Liu Xing , Sun Haozhe , Wang Chong , Ji Chang‐Yin , Li Jiafang , Wang Yang 
Published: September 2023

AbstractThe nano‐kirigami metasurfaces have controllable 3D geometric parameters and dynamic transformation functions and therefore provide a strong spectral regulation capability of thermal emission. Here, the authors propose and demonstrate a dynamic and multifunctional thermal emitter based on deformable nano‐kirigami structures, which can be actuated by electronic bias or mechanical compression. Selective emittance and the variation of radiation intensity/wavelength are achieved by adjusting the geometric shape and the transformation of the structures. Particularly, a thermal management device based on a composite structure of nano‐kirigami and polydimethylsiloxane (PDMS) thin film is developed, which can dynamically switch the state of cooling and heating by simply pressing the device. The proposed thermal emitter designs with strong regulation capability and multiple dynamic adjustment strategies are desirable for energy and sensing applications and inspire further development of infrared emitters.
Cybercrime in India: An analysis of crime against women in ever expanding digital space
Authors: Sankhwar Shweta , Ahuja Rupali , Choubey Tanya , Jain Priyanshi , Jain Tanusha , Verma Muskan 
Published: September 2023

AbstractThe ever expanding digital space and government initiatives like Digital India have increased connectivity, digitization, remote employment which empowered us with technology and made our lifestyle easy and fast but as digitization is enhancing, cyberattacks are proportionally growing. In the initial stage of this study, it was observed from the data analysis and it was evident that women are particularly a soft target of many cybercriminals and cyber fraudsters. Women feel insecure in cyberspace, hence there is a need to dive deeper into our understanding and statistics of cybercrimes against women in India. It becomes necessary to determine the factors that have led to the clear surge of such crimes in recent years. In recent studies no such analysis is done focusing on geographical factors and top most cybercrime types committed against women. Therefore, in this article, prediction for cybercrime trends against women was performed using statistical tools and techniques to provide a better insight into the current scenario revolving around cybercrimes and women. A regressive statistical analysis of cybercrime data of all states of India to understand the current trend of cybercrimes, identification of the most vulnerable states of India and specific cybercrime with their percentage in whole, also where cybercrime afflicted women stand in those numbers. Further, for preventive measures a robust guidelines is proposed to combat cybercrimes for a better future.
Ein neues Bemessungskonzept für dünnwandig kaltgeformte Stahlprofile
Authors: Ungermann Dieter , Lemański Tim , Brune Bettina 
Published: September 2023

AbstractEs wurde ein neues, Eurocode‐konformes Bemessungskonzept für kaltgeformte Stahlprofile entwickelt. Es sieht vor, die Querschnittstragfähigkeit in Anlehnung an AISI S100‐16 – Direct Strength Method basierend auf numerischen Eigenwertanalysen am Bruttoquerschnitt zu berechnen und diese in das Nachweiskonzept nach DIN EN 1993‐1‐3 für globale oder gekoppelte Instabilitäten zu transferieren. Um dieses neue Bemessungskonzept zu verifizieren, wurden experimentelle Untersuchungen an verschiedenen kaltgeformten Stahlprofilen durchgeführt. Mittels numerischer Simulation wurden zusätzlich Parameterstudien durchgeführt.
Deoxynivalenol exposure induces oxidative stress and apoptosis in human keratinocytes via PI3K/Akt and MAPK signaling pathway
Authors: Xu Xiaoxiang , Xi Ningyuan , Chen Jiashe , Zhou Zhiyu , Liu Mengjie , Yan Guorong , Liu Yeqiang 
Published: September 2023

AbstractDeoxynivalenol (DON) is a mycotoxin frequently occurring in human and animal food worldwide, which raises increasing public health concerns. In the present study, we used human keratinocytes (HaCaT cells) as an in vitro model to explore the cytotoxic effect of DON. The results showed that the cells exhibited varying degrees of damage, including decreased cell number and viability, cell shrinkage and floating, when treated with 0.125, 0.25, and 0.5 μg/mL DON for 6, 12, and 24 h, respectively. Furthermore, exposure to DON for 24 h significantly increased the lactate dehydrogenase (LDH) release and intracellular reactive oxygen species (ROS), and prominently decreased the superoxide dismutase (SOD) and catalase (CAT) activity. Additionally, DON exposure induced mitochondrial damage and cell apoptosis through reducing mitochondrial membrane potential. Then, we performed RNA‐sequencing to investigate the molecular changes in HaCaT cells after DON exposure. The RNA‐sequencing results revealed that DON exposure altered the gene expression involved in apoptosis, MAPK signaling pathway, and PI3K/Akt signaling pathway. Moreover, DON exposure significantly decreased the mRNA and protein expression of Bcl‐2, and increased the mRNA and protein expression of Bax, Caspase 3 and COX‐2, the protein expression of PI3K, and the phosphorylation levels of Akt, ERK, p38, and JNK. Taken together, these findings suggest that DON exposure could induce cell damage, oxidative stress, and apoptosis in HaCaT cells through the activation of PI3K/Akt and MAPK pathways.
2,2′,4,4′‐Tetrabromodiphenyl ether and cadmium co‐exposure activates aryl hydrocarbon receptor pathway to induce ROS and GSDME‐dependent pyroptosis in renal tubular epithelial cells
Authors: Sheng Yating , Zhang Chengpeng , Cai Dandan , Xu Guangtao , Chen Shipiao , Li Weijian , Dong Jingjian , Shen Bin , Tang Jie , Xu Long 
Published: September 2023

AbstractWe have previously found that a mixture exposure of 2,2′,4,4′‐tetrabromodiphenyl ether (BDE‐47) and cadmium (Cd) causes kidney damage; however, the mechanism was not fully understood. The aryl hydrocarbon receptor (AhR) is a ligand–receptor transcription factor that plays an important role in the adaptive response or metabolic detoxification of environmental toxins. Thus, this study aimed to examine the role of AhR in kidney toxicity. BDE‐47 (50 μM) or Cd (5 μM) exposure reduced cell viability in renal tubular epithelial cells (HKC), with a larger effect observed in co‐treatment. The cell morphology presented pyroptotic changes, including swollen cells, large bubbles, and plasma membrane pore formation. The gene expressions of AhR, heat shock protein 90 (Hsp90), AhR nuclear translocator (ARNT), and cytochrome P450 1B1 (CYP1B1) were increased, while CYP1A1 was decreased. Reactive oxygen species (ROS) were generated, which was reduced by the AhR antagonist CH223191. The apoptosis, necrosis, and intracellular lactated hydrogenase (LDH) release was elevated, and this was attenuated by N‐acetylcysteine (NAC). Furthermore, the pyroptosis pathway was activated with increased protein levels of cleaved‐caspase‐3 and gasdermin E N‐terminal (GSDME‐NT), while caspase‐8, caspase‐3, and GSDME were decreased. These effects were alleviated by NAC and CH223191. Our data demonstrate a combined effect of BDE‐47 and Cd on nephrotoxicity by activating AhR to induce ROS contributing to GSDME‐dependent pyroptosis, and retardation of the AhR pathway could reduce this toxicity.
Two New Members of the Lanthanoid Bismuth Oxide Oxidosilicates LnBiO[SiO4] with Ln=La and Gd
Authors: Locke Ralf J. C. , Haag Tanja , Hartenbach Ingo , Kurz Melanie V. , Blaschkowski Björn , Schleid Thomas 
Published: September 2023

AbstractThe isostructural lanthanoid bismuth oxide oxidosilicates with the formula LnBiO[SiO4] (Ln=La and Gd) crystallize in the triclinic space group
with the lattice parameters a=571.04(3) pm, b=681.13(4) pm, c=697.98(4) pm and α=105.805(2)°, β=110.456(2)°, γ=99.871(2)°, Vuc=0.23380(2) nm3 for Ln=La and a=554.12(3) pm, b=670.68(4) pm, c=689.57(4) pm and α=104.619(2)°, β=110.793(2)°, γ=99.560(2)°, Vuc=0.22237(2) nm3 for Ln=Gd with Z=2 for both. Colorless single crystals were serendipitously obtained from the reaction of bismuth sesquioxide, bismuth trifluoride and the lanthanoid sesquioxides at 850 °C in unprotected torch‐sealed silica ampoules as SiO2 source. Their crystal structure features Ln3+ cations surrounded by eight oxygen atoms as distorted square antiprisms [LnO8]13−, which are linked via edges with three further polyhedra of this kind to form layers
{[LnO
O
]7−} within the (010) plane. The oxygen environment of the Bi3+ cations has to be described as ψ1‐octahedral (square pyramids [BiO5]7−) with five oxide ligands and the stereochemically active lone pair. Two of them are edge‐linked to form ψ1‐bioctahedra [Bi2O8]10−. Four out of five oxygen atoms belong to discrete [SiO4]4− tetrahedra, which separate
{[OLn
Bi
]4+} chains of trans‐edge connected [OLn2Bi4]10+ tetrahedral, centered by the fifth oxygen atom propagating along [100] for charge compensation. Furthermore, the magnetic properties of GdBiO[SiO4] were investigated, showing Curie‐Weiss behavior without any magnetic ordering phenomena down to lowest temperatures.
Ontology Engineering to Model the European Cultural Heritage: The Case of Cultural Gems
Authors: Alberti Valentina , Cocco Cinzia , Consoli Sergio , Montalto Valentina , Panella Francesco 
Published: September 2023

AbstractCultural gems is a web application conceived by the European Commission’s Joint Research Centre (DG JRC), which aims at engaging people and organizations across Europe to create a unique repository of cultural and creative places. The main goal is to provide a vision of European culture in order to strengthen a sense of identity within a single European cultural realm. Cultural gems maps more than 130,000 physical places in over 300 European cities and towns, and since 2020 it also lists online cultural initiatives. The new release aims, among other, to increase the interoperability of the application. At this purpose, we provide an overview on the current development of an ontology for Cultural gems used to map cultural heritage in European cities by using Linked Open Data (LOD) standards and making the data FAIR, that is Findable, Accessible, Interoperable and Reusable. We provide an overview of the methodology, presenting the structure of the ontology, and the services and tools we are currently building on top.
Electrochemical sensing platform based on screen-printed carbon electrode modified with plasma polymerized acrylonitrile nanofilms for determination of bupropion
Authors: Madej Maria , Trzcińska Agata , Lipińska Justyna , Kapica Ryszard , Fronczak Maciej , Porada Radosław , Kochana Jolanta , Baś Bogusław , Tyczkowski Jacek 
Published: September 2023

Abstract A original electrochemical sensing platform, based on screen-printed electrodes modification with plasma polymerized acrylonitrile (pp-AN) nanofilms is proposed. For that purpose, plasma-enhanced chemical vapor deposition (PECVD) process was conducted in a parallel plate (13.56 MHz) plasma reactor for 2 min with discharge power of 10 W. The surface topography and electrochemical properties of prepared sensors were investigated by X-ray photoelectron spectroscopy, scanning electron microscopy, energy dispersion spectroscopy, electrochemical impedance spectroscopy, and cyclic voltammetry. The electrochemical characteristics of pp-AN/SPCE and pp-AN/SPAuE sensors was investigated for model redox pair [Fe(CN)6]4−/3−. Conducted research confirmed the excellent chemical stability, durability, wide potential window, high signal-to-noise (S/N) ratio, and, most importantly, the ability to standardize the sensors. The pp-AN/SPCE sensor was applied to the determination of bupropion, an antidepressant drug whose intake has increased dramatically during the COVID-19 pandemic. The voltammetric response of pp-AN/SPCE for BUP was linear in two concentration ranges of 0.63–10.0 and 10.0–50.0 μmol L−1, with a detection limit of 0.21 μmol L−1. Satisfactory recoveries (96.2–102%) and good precision (RSD below 4.1%) obtained for environmental and biological samples confirmed the usefulness of the sensor for the analysis of various kinds of samples.
Graphical Abstract
Self-Induced Large-Scale Motions in a Three-Dimensional Diffuser
Authors: Miró Arnau , Eiximeno Benet , Rodríguez Ivette , Lehmkuhl Oriol 
Published: September 2023

AbstractA direct numerical simulation of a three-dimensional diffuser at Reynolds number Re = 10,000 (based on inlet bulk velocity) has been performed using a low-dissipation finite element code. The geometry chosen for this work is the Stanford diffuser, introduced by Cherry et al. (Int. J. Heat Fluid Flow 29:803–811, 2008). Results have been exhaustively compared with the published data with a quite good agreement. Additionally, further turbulent statistics have been provided such as the Reynolds stresses or the turbulent kinetic energy. A proper orthogonal decomposition and a dynamic mode decomposition analyses of the main flow variables have been performed to identify the main characteristics of the large-scale motions. A combined, self-induced movement of the large-scales has been found to originate in the top-right expansion corner with two clear features. A low-frequency diagonal cross-stream travelling wave first reported by Malm et al. (J. Fluid Mech. 699:320–351, 2012), has been clearly identified in the spatial modes of the stream-wise velocity components and the pressure, associated with the narrow band frequency of $$St \in [0.083,0.01]$$

S
t
∈
[
0.083
,
0.01
]

. This movement is caused by the geometrical expansion of the diffuser in the cross-stream direction. A second low-frequency trait has been identified associated with the persisting secondary flows and acting as a back and forth global accelerating-decelerating motion located on the straight area of the diffuser, with associated frequencies of $$St < 0.005$$

S
t
<
0.005

. The smallest frequency observed in this work has been $$St = 0.0013$$

S
t
=
0.0013

. This low-frequency observed in the Stanford diffuser points out the need for longer simulations in order to obtain further turbulent statistics.
Transformations of glucuronoxylan during acid sulphite pulping of eucalyptus dissolving pulp
Authors: Mendes Inês S. F. , Prates António , Evtuguin Dmitry V. 
Published: September 2023

AbstractXylan is the main contaminant of hardwood sulphite dissolving pulp used for the production of regenerated cellulose. The amount of xylan in pulp should not exceed the minimum allowable values and which is not easy to achieve. To control the pulping process, a basic knowledge of xylan removal is essential. In this study, Eucalyptus globulus glucuronoxylan (GX) conversion during acidic Mg-base acid sulphite pulping of dissolving pulp was assessed for the first time in pilot experiments simulating the industrial process. The kinetics of GX degradation and changes in its structure and molecular weight along all pulping steps were evaluated. According to pentosans analysis, more than 60% of wood xylan was removed already in the heating-up step. A pseudo-first-order reaction for xylan degradation at the final pulping temperature of 140–148 °C was obtained with an activation energy of 133.4 kJ/mol. Removal of residual GX from pulp was hampered by its entrapment in cellulose fibril aggregates. The dynamics of xylan deacetylation and depolymerization during pulping in isolated samples was revealed by 2D NMR and SEC techniques, respectively. Overall, the residual xylan structure in pulp is predetermined by its structural heterogeneity in the cell wall, rather than by structural changes occurring during pulping.
Sea level rise risk interactions with coastal property values: a case study of O‘ahu, Hawai‘i
Authors: Tarui Nori , Urbanski Seth , Lam Quang Loc , Coffman Makena , Newfield Conrad 
Published: September 2023

AbstractClimate change-induced sea level rise (SLR) will affect a range of coastal assets and prompt difficult decisions about coastal land use across the world. Several recent studies find that current and projected SLR is associated with relatively lower property values. We contribute to this growing body of research with a case study of O‘ahu, Hawai‘i, which is famed for its beaches as well as valuable coastal real estate. We leverage a dataset that unpacks multiple types of SLR exposure and coastal parcel attributes. We apply property transaction data for the island of O‘ahu through 2019 to investigate the effect of current and expected SLR exposure on residential property prices. We find that exposed properties have already experienced declines in transaction prices, at 9 to 14%, attributed to expectations of exposure to chronic inundation (as opposed to seasonal flooding). The price declines are mainly for multi-dwelling homes as opposed to single family homes. The market response of residential properties to SLR has important implications for coastal management strategies, in particular the viability and timing of programs for retreat.
When Shepherds Shed: Trajectories of Weight-Related Behaviors in a Holistic Health Intervention Tailored for US Christian Clergy
Authors: Yao Jia , Steinberg Dori , Turner Elizabeth L. , Cai Grace Y. , Cameron Jacqueline R. , Hybels Celia F. , Eagle David E. , Milstein Glen , Rash Joshua A. , Proeschold-Bell Rae Jean 
Published: September 2023

AbstractMaintaining healthy behaviors is challenging. Based upon previous reports that in North Carolina (NC), USA, overweight/obese clergy lost weight during a two-year religiously tailored health intervention, we described trajectories of diet, physical activity, and sleep. We investigated whether behavior changes were associated with weight and use of health-promoting theological messages. Improvements were observed in sleep, calorie-dense food intake, and physical activity, with the latter two associated with weight loss. While theological messages were well-retained, their relationship with behaviors depended on the specific message, behavior, and timing. Findings offer insights into weight loss mechanisms, including the role of theological messages in religiously tailored health interventions.
Establishing the link: Does web traffic from various marketing channels influence direct traffic source purchases?
Authors: Filippou Georgios , Georgiadis Athanasios G. , Jha Ashish Kumar 
Published: September 2023

AbstractMarketing professionals and business owners strive to evaluate the effectiveness of their marketing investments. With multiple marketing channels at their disposal, understanding how these channels interact and influence each other is crucial. Digital analytics tools, such as Google Analytics, tend to measure the isolated success of each marketing channel. However, the intertwined effects and interdependencies between channels are often undervalued. This study, therefore, ventures into this territory. It focuses on the association between website traffic from various digital marketing channels and the purchases made by users visiting websites through direct traffic sources. We analyzed 89,394 purchases from an e-commerce business in Europe. We conclude that three marketing channels can explain 61% of the variance. By shedding light on this overlooked aspect, we aim to guide advertisers toward a more holistic understanding of digital marketing channels.
Auto/biographical research on old Mexican women: a methodological and reflexive account
Authors: Makita Meiko 
Published: September 2023

AbstractWhen it comes to presenting qualitative research in a language other than the participants’ native language the decision-making processes involved are not often fully addressed. Drawing on research with 32 Mexican women aged 60 and over and addressing a significant gap in guidance available to bilingual novice researchers and/or aspiring Ph.D. candidates, this article discusses the complexities of shifting between languages while conducting auto/biographical research. It also explores the researcher’s own positionality as insider/outsider and how these issues impact the research outcomes and knowledge production. It particularly highlights the dual role as researcher and Spanish–English translator and provides details about the methodological decisions undertaken regarding wording selection and interpretation across languages. Ultimately, this article contends that cross-language researchers need to systematically address the unique translation issues involved and make explicit the dilemmas and consequences of moving between languages in which participants’ auto/biographies are analysed, written-up and published.