bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estruturas de interação no tratamento psicodinâmico de uma paciente com Transtorno de Personalidade Borderline
Authors: Nardi Suzana Catanio dos Santos , Feijó Luan Paris , Bittencourt Aline Alvares , Serralta Fernanda Barcellos , Benetti Silvia Pereira da Cruz 
Published: February 2023

Estruturas de interação são padrões repetitivos que ocorrem entre terapeuta e paciente, mesmo que não sejam conscientes por ambos. Na pesquisa empírica, elas ajudam a compreender como se estabelece o processo de mudança em psicoterapia. Nesse sentido, esta investigação utilizou 68 sessões de psicoterapia psicanalítica de um caso do uma jovem paciente com Transtorno de Personalidade Borderline (TPB) com o objetivo de identificar as estruturas de interação e sua correlação com o tempo de tratamento. Os dados foram gravados em vídeo e posteriormente codificadas através do Psychotherapy Process Q-Set (PQS), por duplas de juízes treinados na metodologia Q-Sort. A partir desses dados, foi realizada a análise fatorial do tipo Q de componentes principais que indicou quatro estruturas de interação, sendo Fator 1: Colaborativo; Fator 2: Resistência; fator 3: Aliança/Ruptura e fator 4: Apoio/Encorajamento. As estruturas indicaram que a interação se voltou para o trabalho de manutenção da interação colaborativa, através de uma posição empática do terapeuta, direcionado para o reconhecimento dos estados internos do paciente. Apesar do trabalho colaborativo, a resistência também surgiu como um padrão repetitivo. O terapeuta se tornou diretivo com intervenções estruturadas e questionando o paciente, desta forma contribuindo para o desenvolvimento da capacidade de mentalização. Implicações sobre o processo psicoterápico e indicações para estudos futuros são apresentados com o intuito de contribuir na compreensão sobre o tratamento de pacientes com TPB em psicoterapia psicodinâmica.
MRI assessment of femoral head docking following closed reduction of developmental dysplasia of the hip
Authors: Fu Zhe , Zhang Zhongli , Deng Shuzhen , Yang Jianping , Li Bing , Zhang Huadong , Liu Jun 
Published: February 2023

Aims Eccentric reductions may become concentric through femoral head ‘docking’ (FHD) following closed reduction (CR) for developmental dysplasia of the hip (DDH). However, changes regarding position and morphology through FHD are not well understood. We aimed to assess these changes using serial MRI. Methods We reviewed 103 patients with DDH successfully treated by CR and spica casting in a single institution between January 2016 and December 2020. MRI was routinely performed immediately after CR and at the end of each cast. Using MRI, we described the labrum-acetabular cartilage complex (LACC) morphology, and measured the femoral head to triradiate cartilage distance (FTD) on the midcoronal section. A total of 13 hips with initial complete reduction (i.e. FTD < 1 mm) and ten hips with incomplete MRI follow-up were excluded. A total of 86 patients (92 hips) with a FTD > 1 mm were included in the analysis. Results At the end of the first cast period, 73 hips (79.3%) had a FTD < 1 mm. Multiple regression analysis showed that FTD (p = 0.011) and immobilization duration (p = 0.028) were associated with complete reduction. At the end of the second cast period, all 92 hips achieved complete reduction. The LACC on initial MRI was inverted in 69 hips (75.0%), partly inverted in 16 hips (17.4%), and everted in seven hips (7.6%). The LACC became everted-congruent in 45 hips (48.9%) and 92 hips (100%) at the end of the first and second cast period, respectively. However, a residual inverted labrum was present in 50/85 hips (58.8%) with an initial inverted or partly inverted LACC. Conclusion An eccentric reduction can become concentric after complete reduction and LACC remodelling following CR for DDH. Varying immobilization durations were required for achieving complete reduction. A residual inverted labrum was present in more than half of all hips after LACC remodelling. Cite this article: Bone Joint J 2023;105-B(2):140–147.
What are the resection accuracy and guide-fitting errors associated with 3D-printed, patient-specific resection guides for bone tumour resections?
Authors: Lee Seung H. , Kim Wanlim , Lee Jong S. 
Published: February 2023

Aims This study aimed to analyze the accuracy and errors associated with 3D-printed, patient-specific resection guides (3DP-PSRGs) used for bone tumour resection. Methods We retrospectively reviewed 29 bone tumour resections that used 3DP-PSRGs based on 3D CT and 3D MRI. We evaluated the resection amount errors and resection margin errors relative to the preoperative plans. Guide-fitting errors and guide distortion were evaluated intraoperatively and one month postoperatively, respectively. We categorized each of these error types into three grades (grade 1, < 1 mm; grade 2, 1 to 3 mm; and grade 3, > 3 mm) to evaluate the overall accuracy. Results The maximum resection amount error was 2 mm. Out of 29 resection amount errors, 15 (51.7%) were grade 1 errors and 14 (38.3%) were grade 2 errors. Complex resections were associated with higher-grade resection amount errors (p < 0.001). The actual resection margins correlated significantly with the planned margins; however, there were some discrepancies. The maximum guide-fitting error was 3 mm. There were 22 (75.9%), five (17.2%), and two (6.9%) grade 1, 2, and 3 guide-fitting errors, respectively. There was no significant association between complex resection and fitting error grades. The guide distortion after one month in all patients was rated as grade 1. Conclusion In terms of the accurate resection amount according to the preoperative planning, 3DP-PSRGs can be a viable option for bone tumour resection. However, 3DP-PSRG use may be associated with resection margin length discrepancies relative to the planned margins. Such discrepancies should be considered when determining surgical margins. Therefore, a thorough evaluation of the preoperative imaging and surgical planning is still required, even if 3DP-PSRGs are to be used. Cite this article: Bone Joint J 2023;105-B(2):190–197.
Three to six tissue specimens for histopathological analysis are most accurate for diagnosing periprosthetic joint infection
Authors: Sigmund Irene K. , Yeghiazaryan Lusine , Luger Markus , Windhager Reinhard , Sulzbacher Irene , McNally Martin A. 
Published: February 2023

Aims The aim of this study was to evaluate the optimal deep tissue specimen sample number for histopathological analysis in the diagnosis of periprosthetic joint infection (PJI). Methods In this retrospective diagnostic study, patients undergoing revision surgery after total hip or knee arthroplasty (n = 119) between January 2015 and July 2018 were included. Multiple specimens of the periprosthetic membrane and pseudocapsule were obtained for histopathological analysis at revision arthroplasty. Based on the Infectious Diseases Society of America (IDSA) 2013 criteria, the International Consensus Meeting (ICM) 2018 criteria, and the European Bone and Joint Infection Society (EBJIS) 2021 criteria, PJI was defined. Using a mixed effects logistic regression model, the sensitivity and specificity of the histological diagnosis were calculated. The optimal number of periprosthetic tissue specimens for histopathological analysis was determined by applying the Youden index. Results Based on the EBJIS criteria (excluding histology), 46 (39%) patients were classified as infected. Four to six specimens showed the highest Youden index (four specimens: 0.631; five: 0.634; six: 0.632). The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of five tissue specimens were 76.5% (95% confidence interval (CI) 67.6 to 81.4), 86.8% (95% CI 81.3 to 93.5), 66.0% (95% CI 53.2 to 78.7), and 84.3% (95% CI 79.4 to 89.3), respectively. The area under the curve (AUC) was calculated with 0.81 (as a function of the number of tissue specimens). Applying the ICM and IDSA criteria (excluding histology), 40 (34%) and 32 (27%) patients were categorized as septic. Three to five specimens had the highest Youden index (ICM 3: 0.648; 4: 0.651; 5: 0.649) (IDSA 3: 0.627; 4: 0.629; 5: 0.625). Conclusion Three to six tissue specimens of the periprosthetic membrane and pseudocapsule should be collected at revision arthroplasty and analyzed by a pathologist experienced and skilled in interpreting periprosthetic tissue. Cite this article: Bone Joint J 2023;105-B(2):158–165.
Total hip arthroplasty versus hemiarthroplasty for treatment of femoral neck fractures
Authors: Tohidi Mina , Mann Stephen M. , Groome Patti A. 
Published: February 2023

Aims This study aimed to describe practice variation in the use of total hip arthroplasty (THA) for older patients with femoral neck fracture and to determine the association between patient, surgeon, and institution factors and treatment with THA. Methods We performed a cross-sectional analysis of 49,597 patients aged 60 years and older from Ontario, Canada, who underwent hemiarthroplasty or THA for femoral neck fracture between 2002 and 2017. This population-based study used routinely collected healthcare databases linked through ICES (formerly known as the Institute for Clinical Evaluative Sciences). Multilevel logistic regression modelling was used to quantify the association between patient, surgeon, and institution-level variables and whether patients were treated with THA. Variance partition coefficient and median odds ratios were used to estimate the variation attributable to higher-level variables and the magnitude of effect of higher-level variables, respectively. Results Over the study period, 9.4% of patients (n = 4,638) were treated with THA. Patient factors associated with higher likelihood of treatment by THA included: younger age, male sex, and diagnosis with rheumatoid arthritis. Long-term care residence, use of home care services prior to hip fracture, diagnosis of dementia, higher comorbidity burden, and the most marginalized group were negatively associated with treatment by THA. Treating surgeon and institution accounted for 54.2% and 17.8% of the total variation in treatment with THA, respectively. Surgeon volume of THA procedures in the 365 days prior to surgery was the strongest higher-level predictor of treatment with THA. Specific treating surgeons and institutions still accounted for significant proportions of the variability in treatment with THA (40.3% and 19.5% of total observed variation, respectively) after controlling for available patient, surgeon, and institution-level variables. Conclusion The strongest predictors for treatment of patients with femoral neck fracture with THA were patient age, treating surgeon, and treating institution. This practice variation highlights differential access to care for patients. Cite this article: Bone Joint J 2023;105-B(2):180–189.
February 2023 Pulmonary Case of the Month: SCID-ing to a Diagnosis
Authors:   Mayo Clinic Arizona, Phoenix, AZ USA, Wesselius Lewis 
Published: February 2023

History of Present Illness A 40-year-old man was referred for management of respiratory symptoms of cough, sputum production and shortness of breath. He has a history of respiratory infections that began in early childhood. Sputum cultures were positive for Pseudomonas. He is currently using oxygen at night and occasionally during the day. Past Medical History, Family History and Social History •	Childhood diagnosis of asthma. •	Multiple colds and pneumonias in the past. •	No family history of a similar problem. •	He has never smoked. •	Denies any occupational exposure. Physical Examination •	Vital Signs: O2 Sat 88% on RA •	Chest: diminished breath sounds, no wheezes •	Heart: regular rate and rhythm without murmur •	Extremities: mild clubbing present, no edema Pulmonary Function Testing Pulmonary function testing (PFTs) was performed with results as below (Figure 1). Thoracic CT Scan A thoracic CT was performed (Figure 2). Which of the following is/are true? 1.	PFTs show severe obstructive …
PENSANDO UM CURRÍCULO ESCOLAR QUEER MESTIÇO: AS CONTRIBUIÇÕES DA TEORIA QUEER ARTICULADA A METODOLOGIA INTERSECCIONAL
Authors: Carvalho Rubem Viana  de , Silva Luiz Felipe de Oliveira , Lage Allene Carvalho 
Published: February 2023

Neste trabalho refletimos sobre as contribuições da teoria queer articulada à metodologia interseccional como possibilidade de pensarmos outros currículos escolares que sejam comprometidos com o questionamento e enfrentamento à normatividade, cisheteronormatividade, ao racismo e as LGBTfobias, ou seja, currículos múltiplos e não únicos. Para tanto, levantamos a seguinte questão: como a teoria queer pensada a partir de uma metodologia interseccional pode contribuir para pensarmos currículos escolares antirracistas e anti-LGBTfóbicos comprometidos com a multiplicidade? Para nos ajudar a compreender essas relações utilizamos como referencial teórico ideias de Foucault (1988), Butler (2003), Scott (1975), Rubin (2017), Louro (2001), Miskolci (2017) e Borba (2020), além de autores/as como Crenshaw (2002) e Oliveira e Sabino (2020), propondo implementações à teoria queer a partir da proposição da necessidade de articular às categorias de gênero e sexualidades, a categorias como raça e classe para pensarmos as singularidades do Brasil e da América Latina. Enquanto metodologia a análise é qualitativa feita a partir de uma revisão bibliográfica de caráter exploratória. Enquanto procedimento de análise utilizamos a perspectiva de análise de conteúdo de Bardin (1977). As conclusões apontam que pensar o currículo escolar a partir de uma perspectiva queer mestiça dentro de uma pluralidade geocultural pode contribuir para a criação de currículos mais próximos as diferenças, assim como com a formação de identidades abertas, que podem desafiar preconceitos como o racismo e as LGBTfobias, questionando os modelos hegemônicos e propondo alternativas criativas a partir da torção das opressões.
On projections of free semialgebraic sets
Authors: Drescher Tom , Netzer Tim , Thom Andreas 
Published: February 2023

Abstract
We examine to what extent a projection theorem is possible in the non-commutative (free) setting. We first review and extend some results that count against a full free projection theorem. We then obtain a weak version of the projection theorem: projections along linear and separated variables yield semialgebraically parametrised free semi-algebraic sets.
Multiple ECG segments denoising autoencoder model
Authors: Samann Fars , Schanze Thomas 
Published: February 2023

Abstract

Objectives
Denoising autoencoder (DAE) with a single hidden layer of neurons can recode a signal, i.e., converting the original signal into a noise-reduced signal. The DAE approach has shown a good performance in denoising bio-signals, like electrocardiograms (ECG). In this paper, we study the effect of correlated, uncorrelated and jittered datasets on the performance of the DAE model.

Methods
Vectors of multiple concatenated ECG segments of simultaneously recorded Einthoven recordings I, II, III are considered to establish the following dataset cases: (1) correlated, (2) uncorrelated, and (3) jittered. We consider our previous work in finding the optimal number of hidden neurons receiving the input signal with respect to signal quality and computational burden by applying Akaike’s information criterion. To evaluate DAE, these datasets are corrupted with six types of noise, namely mix noise (MX), motion artifact noise (MA), electrode movement (EM), baseline wander (BW), Gaussian white noise (GWN) and high-frequency noise (HFN), to simulate real case scenario. Spectral analysis is used to study the effects of noise whose power spectrum may overlap with the power spectrum of the wanted signal on DAE performance.

Results
The simulation results show (a) that the number of hidden neurons to denoise multiple correlated ECG is much lower than for jittered signals, (b) QRS-complex based ECG alignment preferable, (c) noises with slightly overlapping power spectrum, like BW and HFN, can be easily removed with sufficient number of neurons, while the noise with completely overlapping spectrum, like GWN, requires a very low-dimensional and thus coarser reduction to recover the signal.

Conclusions
The performance of DAE model in terms of signal-to-noise ratio improvement and the required number of hidden neurons can be improved by utilizing the correlation among simultaneous Einthoven I, II, III records.
Assessment of humoral and cellular immunity after bivalent BNT162b2 vaccination and potential association with reactogenicity
Authors: Salvagno Gian Luca , Pighi Laura , Henry Brandon M. , Valentini Myriam , Tonin Beatrice , Bragantini Damiano , Gianfilippi Gianluca , De Nitto Simone , Plebani Mario , Lippi Giuseppe 
Published: February 2023

Abstract

Objectives
This study investigated the feasibility and clinical value of using a novel, automated and high-throughput SARS-CoV-2 Interferon Gamma Release Assay (IGRA), combined with total anti-SARS-CoV-2 antibodies assessment, for evaluating the immune response after bivalent BNT162b2 vaccination.

Methods
A cohort of healthcare workers, who already underwent primary vaccination and boosting with monovalent BNT162b2 vaccine, received a booster dose of the new BNT162b2 bivalent formulation. Blood samples were taken immediately before vaccination (T0) and 1 month afterwards (T1). Humoral and cellular immunity were assayed with Roche Elecsys Anti-SARS-CoV-2 and Roche Elecsys IGRA SARS-CoV-2, respectively.

Results
The study population consisted of 51 subjects (median age: 43 years; 51% females). Total anti-SARS-CoV-2 antibodies and IGRA SARS-CoV-2 values increased at T1 from 9,050 to 25,000 BAU/mL (p<0.001), and from 0.44 to 0.78 IU/mL (p=0.385), accounting for median increase of 2.0 and 1.6 folds, respectively. Increased T1 values of total anti-SARS-CoV-2 antibodies and IGRA SARS-CoV-2 were recorded in 100% and 68.6% subjects, respectively. In those with baseline values below the median, post-vaccine levels displayed larger increases of 3.3 and 5.1 folds for anti-SARS-CoV-2 total antibodies and IGRA SARS-CoV-2, respectively. The variation of total anti-SARS-CoV-2 antibodies was inversely associated with their T0 values (r=−0.97; p<0.001), whilst that of IGRA SARS-CoV-2 was inversely associated with its T0 value (r=−0.58; p<0.001). No other signifcant associations were found with demographical or clinical variables, including side effects.

Conclusions
The bivalent BNT162b2 vaccine booster enhances humoral and cellular immunity against SARS-CoV-2, especially in recipients with lower baseline biological protection.
Diagenesis and evolution of deep tight reservoirs: A case study of the fourth member of Shahejie Formation (cg: 50.4-42 Ma) in Bozhong Sag
Authors: Zhang Juan , Wang Chenchen , Jia Yunqian , Wu Qianyu 
Published: February 2023

Abstract
This study focused on the deep tight sandstone reservoir (DTSR) of the fourth member of the Shahejie Formation in the Bozhong Sag, Bohai Bay Basin, a special type of reservoir. To reveal the diagenesis and evolution of the reservoir in the study area, cores observation, thin section identification, scanning electron microscopy, grain size analysis, and petrophysical properties measurements are available to analyze the mechanics of diagenesis and densification processes. The recognition is agreed on that (1) the lithology of the fourth member is mainly composed of lithic arkose and feldspathic lithic sandstone with low compositional maturity, and grain sizes vary from middle to coarse; (2) the porosity of reservoir ranges from 4 to 11.5% (av. 6.8%), which belongs to the medium low porosity sandstone reservoir; the pore structure is complex and the type of pore spaces is mainly secondary pore, while original pores are less developed due to the deep distribution of strata; (3) based on the quantitative calculation of porosity of the DTSR, it was identified that compaction is the main reason for sandstone reservoir densification, with an average porosity reduction of 62%, followed by cementation filling intergranular pores with an average pore reduction rate of 25.1%. Dissolution plays a constructive role in improving porosity, with an average increase rate of 18.5%.
Antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection
Authors: Chukwu Ifeoma L. , Ugwu Malachy C. , Iroha Ifeanyi R. , Mbagwu Ikechukwu S. , Okafor Ugochukwu U. , Ajaghaku Amara A. 
Published: February 2023

Abstract

Background
This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.

Methods
The whole plant was cold-macerated with methanol. The liquid–liquid partitioning of the extract with n-hexane, ethyl acetate, butanol, and water produced various fractions of the extract. Infection was established by the inoculation of T. brucei brucei-infected red blood cells in the animals. Treatment with the extract and fractions was done orally for 5 days postinfection at 200 and 400 mg/kg doses. Diminazene aceturate 3.5 mg/kg and 5 mL/kg 10% Tween 80 served as standard and vehicle control, respectively. Parasite load, packed cell volume (PCV), animal body weight, and survival as well as serum liver function enzymes’ activities were also assessed.

Results
The extract and the n-hexane fraction showed the presence of all the tested phytocompounds except tannins and cardiac glycosides, respectively. The extract showed a reduction in parasitemia while the order of activity for the fractions was n-hexane ≫ water ≫ butanol ≫ ethyl acetate. The n-hexane fraction produced complete protection against parasite-induced mortality just like the reference standard and a higher increase in PCV compared with the reference standard. The extract, n-hexane, and water fractions showed protection against infection-induced liver damage with a significant (P < 0.05) difference when compared to the vehicle control group.

Conclusion

A. mexicana showed antitrypanosomal activity which may be attributed to the presence of phytocompounds particularly saponins, which were present in the extract and fractions that showed antitrypanosomal activity but absent in fractions that showed no or weak antitrypanosomal activity.
The role of prior exposure in the likelihood of adopting the Intentional Stance toward a humanoid robot
Authors: Roselli Cecilia , Marchesi Serena , De Tommaso Davide , Wykowska Agnieszka 
Published: February 2023

Abstract
One of the key questions in human–robot interaction research is whether humans perceive robots as intentional agents, or rather only as mindless machines. Research has shown that, in some contexts, people do perceive robots as intentional agents. However, the role of prior exposure to robots as a factor potentially playing a role in the attribution of intentionality is still poorly understood. To this end, we asked two samples of high school students, which differed with respect to the type of education they were pursuing (scientific/technical vs. artistic) to complete the InStance Test, measuring individual tendency to attribute intentionality toward robots. Results showed that, overall, participants were more prone to attribute intentionality to robots after being exposed to a theoretical lecture about robots’ functionality and use. Moreover, participants’ scientific/technical education resulted in a higher likelihood of attribution of intentionality to robots, relative to those with artistic education. Therefore, we suggest that the type of education, as well as individually acquired knowledge, modulates the likelihood of attributing intentionality toward robots.