bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análise numérica para classificação dos Objetivos de Desenvolvimento Sustentável segundo relação com os indicadores "Déficit Habitacional" e "Inadequação Domiciliar"
Authors: Santanna Gabriel Miranda , Nascimento Ana Paula Branco do , Yoshikawa Nestor Kenji 
Published: March 2023

O tema “habitação” demonstra ser uma questão complexa que ultrapassa diferentes formas de compreensão. Sua análise depende do aspecto com que se observa, assumindo diferentes significados ora complementares, ora paradoxais. A denominação no campo da habitação “déficit” representa um aspecto mais metodológico que investiga o número de moradias necessárias para suprir necessidades habitacionais da população mais carente. O objetivo desta pesquisa é identificar quais os Objetivos de Desenvolvimento Sustentável (ODS) possuem maior relação com os indicadores habitacionais. Por meio de três métodos complementares de atribuição de pontos variados às suas 169 metas, foram obtidos scores relacionais classificáveis. Identificou-se que estas relações ocorrem em via dupla de contribuição, sendo os melhores resultados atribuídos aos ODS 1 (Erradicação da pobreza), ODS 6 (Água potável e saneamento), ODS 7 (Energia limpa e acessível) e ODS 11 (Cidades e Comunidades Sustentáveis). Conclui-se que os ODS 1 e 11 tiveram os melhores resultados, confirmando o impacto da redução da pobreza e o desenvolvimento adequado das cidades como forma de aumentar o acesso das pessoas à moradia de qualidade.
PALAVRA-CHAVE: Objetivos de Desenvolvimento Sustentável, Indicadores habitacionais, investigação de relação
Efficacy and safety of segmental spinal anaesthesia in laparoscopic cholecystectomy: A prospective study
Authors: Singhal Geetanjali , Mathur B. L , Mathur A K 
Published: March 2023

Laparoscopic cholecystectomy is usually conducted under general anaesthesia(GA) which has its own limitations and may be associated with certain complications. This single-arm prospective interventional study was done to assess the safety and efficacy of thoracic segmental spinal anaesthesia(TSSA) as a sole anaesthetic procedure in patients undergoing laparoscopic cholecystectomy. TSSA was administered to 50 patients of the American Society of Anaesthesiologists physical status 1, 2, 3, who were scheduled for elective laparoscopic cholecystectomy (1.5 ml of 0.75% ropivacaine with dexmedetomidine 6 µg as an adjuvant was injected in one of the intervertebral spaces between T7- T12). The primary objective of the study was to evaluate the efficacy and safety of TSSA to provide complete surgical anaesthesia in terms of the total number of cases converted to GA. The data was analysed using SciPy(version 1.3.1), a statistical analysis package, in Python programming language (version 3.7.4). Our study revealed that TSSA provided complete surgical anaesthesia in 48 patients and in two patients there was a failure to achieve adequate sensory block and GA had to be administered. The median time for full sensory regression was 90 min and the median time for complete motor regression was 60 min. No major intraop or postop adverse event was noted.TSSA offers safe and satisfying operating conditions for elective laparoscopic cholecystectomy. This technique practised with caution can provide a useful alternative to GA, especially in conditions where GA may have limitations.
A study of the effects of intravenous magnesium sulphate on post-operative atrial fibrillation in patients undergoing off pump coronary artery bypass grafting (CABG)
Authors: Mukherjee Somalia , Pati Gautam , Kumar Palash , Khan Dibyendu , Sengupta Saikat 
Published: March 2023

Atrial fibrillation (AF) occurs in almost 30% of patients undergoing coronary artery bypass grafting (CABG). Around 80% of these patients have decreased levels of total and ionized serum magnesium postoperatively. The association between magnesium deficiency and post CABG AF is still undetermined. Therefore, a large variety of prophylactic strategies have been assessed including perioperative magnesium administration. However, the efficacy is still questionable. The aim of this study was to find out any correlation of serum magnesium levels with the incidence of post-operative atrial fibrillation in patients undergoing off pump CABG and whether magnesium supplementation modifies the incidence. One hundred fifty patients undergoing CABG were selected and divided into treatment and control groups. Perioperative serum magnesium assays were done, and patients were monitored in the postoperative period for occurrence of Atrial Fibrillation. The risk of post CABG atrial fibrillation was more among females, obese patients, patients with EF &#60; 50% and RWMA. Post-operative AF occurred in 5 patients in the treatment group (n = 75) and 11 patients in the control group (n = 75). : The proportion of patients with post-operative atrial fibrillation among cases (6.7%) was lower than that of controls (14.7%) which may indicate an important role of magnesium in prevention of AF following cardiac surgeries. The results however didn’t reach a statistical significance which could be due to sample size, the duration and design of the study and the period of post-operative AF monitoring.
Anaesthetic implications in a case of super obesity with multiple comorbidities: A conundrum of challenges
Authors: Narayanan K Sathya , Ganesan Ilango , Rajan Gowtham , Dhanabal Nithya , Mary Teresa , Aarthy Rajalakshmy 
Published: March 2023

The fast paced lifestyle with no control over diet and lack of exercise has led to rapid rise in obesity in worldwide population. India being a developing country is no exception to this.A body mass index (BMI) ≥50 kg m, referred to as super obese necessitates optimum anaesthetic expertise during perioperative period. We faced a conundrum of challenges while managing a case of necrotizing fascitis in a superobese patient with multiple comorbidities.Peripheral nerve block was an ideal technique for this patient but for local site skin infection and deep nerve location, spinal anaesthesia with 5 inch (12.7 cm) spinal needle was administered.Regional anaesthesia in obese patients comes with a lot of difficulties including localizing the intervertebral space, narrow subarachnoid space, increased pressure, positioning the patient. Restricted fluid intake due to acute kidney injury leading to decreased preload compounds the above factors.
A prospective, post-marketing surveillance (PMS) study to monitor the safety of fixed dose combination of Triprolidine Hydrochloride IP 2.5 mg and Phenylephrine Hydrochloride IP 5 mg [Recofast Tablets] for the symptomatic relief in patients with upper respiratory tract infections
Authors: Kadoo Sachin Madhukar , Patil Preksha Pramod 
Published: March 2023

Upper Respiratory Tract Infection (URTI) is the most frequent illness in humans. The vast majority of acute upper respiratory tract infections are caused by viruses. These cause a variety of patient diseases including acute bronchitis, common cold, influenza, and respiratory distress syndromes.The study was conducted in patients with upper respiratory tract infections to see if the medication provides symptomatic relief in these conditions. Other conditions like allergic rhinitis and influenza were also included in the study for symptomatic relief.This is an open label, multicentric, active Post Marketing Surveillance (PMS) study with an objective to assess safety of fixed dose combination regarding Recofast tablets (Triprolidine Hydrochloride IP 2.5 mg and Phenylephrine Hydrochloride IP 5 mg) which was evaluated in 150 participants from different geographical regions. And then results were documented. A total of 19 (13%) patients recorded minor adverse event from these regions. Out of 150 patients 95 were male & 55 were female. All the patients were in the range of 18-80 years.No significant adverse events were observed during the course of the study, only 13% patients recorded minor adverse events from all regions. Thus this formulation is completely safe and effective in the management of Upper Respiratory Tract Infections and allergies.
STEM Career Pathways for Transition-Age Youth With Disabilities
Authors: Chun Jina , Zhou Kaiqi , Rumrill Stuart , Tittelbach Tracy 
Published: March 2023

Background:Although there is an increasing demand for workers in STEM fields, people with disabilities are underrepresented in STEM educational programs and related occupations. Among those who achieved competitive integrated employment after serving under an Individualized Plan for Employment (IPE) by the state-federal vocational rehabilitation (VR) system, only 5.3% of individuals with disabilities were engaged in STEM jobs/careers during the years 2017–2019. Of those with an employment outcome in STEM fields, 8,348 (40.9%) were transition-age youth aged 14–24.Objective:Using Rehabilitation Service Administration (RSA-911) data for the fiscal years from 2017 to 2019, the current study investigated the characteristics of transition-age youth with disabilities aged 14–24 in the state-federal VR system that predicted employment outcomes in STEM fields.Methods:A logistic regression analysis was used to examine the associations between individual characteristics and STEM career attainment.Findings:Results illustrated that gender, race, living arrangement, and the receipt of general assistance/SSI/SSDI/TANF predicted employment outcomes in STEM fields.Conclusions:The research findings provide support for the understanding of demographic characteristics of transition-age youth with disabilities successfully closed in STEM jobs/careers after serving under an IPE. A discussion of the strategies and interventions associated with promoting career development and decisions toward the STEM field for transition-age youth with disabilities is provided.
Assessment of Resveratrol's Effects Comparatively with Zinc in Experimental Rat Testicular Damage Induced by Cyclophosphamide
Authors: ŞİRİN Cansın , TOMRUK Canberk , KARADADAŞ Elif , DENİZLİOĞLU Burcu , ERCAN Gülinnaz , SUNER Aslı , YILMAZ Özlem 
Published: March 2023

Cyclophosphamide is a well-known alkylating cytotoxic chemotherapeutic agent.
Aim: To investigate protective effects of Resveratrol in combination or comparison with Zinc in experimental testicular injury induced by Cyclophosphamide is studied for the first time in literature.
Materials and Methods: Rats (n=63) were randomly divided into 9 groups. After 21 days of drug administration biochemical and histological analysis were performed. Daily water consumption, body weights and weight of testes were measured. Johnsen’s testicular scoring and sperm morphology were evaluated. Hematoxylin&Eosin, Periodic acid-Schiff and Masson's trichrome stainings and iNOS, eNOS and CD34 antibodies were applied histologically. To determine oxidative stress, MDA and CAT values were determined. Statistically, one-way ANOVA with post Hoc Tukey HSD test for multiple comparisons was performed via IBM SPSS Version 25.0.
Results: Cyclophosphamide caused an increase in testicular MDA levels due to elevated oxidant stress. Testicular MDA levels significantly decreased in Zinc and Resveratrol groups which revealed protective effects related to Cyclophosphamide treatment, while no significant improvement was observed for control and saline groups. However, the most significant decrease was observed in MDA for Cyclophosphamide+Zn+Resveratrol group in comparison to Cyclophosphamide. Telocytes, which are lately defined novel cells, were detected in the interstitium encircling seminiferous tubules as a sheath immunohistochemically.
Conclusion: Not only Resveratrol and Zinc, but also their optimum administration separately protects testes in Cyclophosphamide treatment groups. Clinical adaptations of this in vivo model may lead to novel futuristic ideas in preventing infertility due to cancer chemotherapy.
The Study of Adherence to Drug Therapy at the Stage of Outpatient Follow-up in Patients with Acute Myocardial Infarction (Data from the PROFIL-IM Registry)
Authors: Kalaydzhyan E. P. , Kutishenko N. P. , Lukina Yu. V. , Sichinava D. P. , Martsevich S. Yu. , Drapkina O. M. 
Published: March 2023

Aim. To assess adherence to the recommended therapy at the stage of outpatient follow-up and its impact on long-term outcomes in patients after acute myocardial infarction based on the materials of the prospective PROFILE-IM registry.Material and methods. The PROFILE-IM register included 160 patients who applied to one of the polyclinics in Moscow after a myocardial infarction. The combined endpoint (CE) included death from any cause, cardiovascular events (nonfatal myocardial infarction, nonfatal cerebral stroke), emergency hospitalizations for cardiovascular diseases, significant cardiac arrhythmias. Patients' adherence to therapy was assessed using the original questionnaire "Scale of Adherence of the National Society of Evidence-based Pharmacotherapy" (NODF) and a direct standardized patient survey by a doctor about taking medications. Visits to the doctor were carried out every two months, data from the first year of patient follow-up are presented.Results. In a personal interview with a doctor, the ratio of the proportion of committed, partially committed and non-committed patients did not change significantly over the entire follow-up period, while the proportion of committed patients was 81-85%. The "NODF Adherence Scale" showed that the proportion of non-committed patients was about 10 times higher than with direct patient responses to the doctor, and the proportion of non-committed and partially committed patients remained high at all stages of follow-up (respectively 28% and 10% at the beginning of the study, 18% and 10% at the end of the study). Among the main factors of non-commitment, there was a decrease in the importance of forgetfulness and an increase in factors such as fear of side effects of medications, doubt about the need for long-term use of medications and well-being. A direct relationship of adherence with the male sex, the presence of hypertension, a feedback relationship with alcohol consumption was revealed. The risk of CE in non-committed patients was higher compared to the group of committed and partially committed patients (p<0.01).Conclusion. The proportion of non-committed and partially committed patients remained high at all stages of follow-up. There was a direct relationship between adherence to therapy with the male sex, the presence of hypertension in the anamnesis, and a feedback relationship with alcohol consumption. Low adherence to therapy significantly increased the risk of cardiovascular events.
Ethics Principles for Artificial Intelligence–Based Telemedicine for Public Health
Authors: Tiribelli Simona , Monnot Annabelle , Shah Syed F. H. , Arora Anmol , Toong Ping J. , Kong Sokanha 
Published: March 2023

The use of artificial intelligence (AI) in the field of telemedicine has grown exponentially over the past decade, along with the adoption of AI-based telemedicine to support public health systems. Although AI-based telemedicine can open up novel opportunities for the delivery of clinical health and care and become a strong aid to public health systems worldwide, it also comes with ethical risks that should be detected, prevented, or mitigated for the responsible use of AI-based telemedicine in and for public health. However, despite the current proliferation of AI ethics frameworks, thus far, none have been developed for the design of AI-based telemedicine, especially for the adoption of AI-based telemedicine in and for public health. We aimed to fill this gap by mapping the most relevant AI ethics principles for AI-based telemedicine for public health and by showing the need to revise them via major ethical themes emerging from bioethics, medical ethics, and public health ethics toward the definition of a unified set of 6 AI ethics principles for the implementation of AI-based telemedicine. (Am J Public Health. 2023;113(5):577–584. https://doi.org/10.2105/AJPH.2023.307225 )
Reconstruction of a Pediatric Lateral Femoral Condyle After Septic Necrosis with a Free Vascularized Fibular Epiphysis
Authors: El-Gammal Tarek Abdalla , Refai Omar Ahmed , Morsy Mohamed , Eisa Amr Atef 
Published: March 2023

Case:
A 5-year-old girl presented with severe valgus deformity of the right knee after septic necrosis of the lateral femoral condyle. Reconstruction was performed using the contralateral proximal fibular epiphysis on the anterior tibial vessels. Union was evident after 6 weeks, and full weight bearing was permitted after 12 weeks. Two years of follow-up showed no deformity or length discrepancy and 90° range of motion.

Conclusion:
The pattern of 1 femoral condyle resorption due to osteomyelitis is a rare presentation. The presented method of reconstruction could be implemented as a novel technique to reconstruct the growing knee joint in such a condition.
The critical role of recycling of post-Grenvillian, Neoproterozoic sediments for Phanerozoic Laurentian clastic systems: evidence from detrital-zircon and -monazite geochronology and textures
Authors: Moecher David P. , Zotto Steven C. , Samson Scott D. 
Published: March 2023

ABSTRACTLithic and quartz arenites of the Central Appalachian Basin deposited by late Paleozoic Laurentian fluvial systems are widely interpreted to be sourced by recycling of late Precambrian and early Paleozoic clastic sequences in the Appalachian Orogen. U-Pb and (U-Th)/He age distributions for detrital-zircon and Th-Pb age distributions for detrital-monazite, detrital-zircon and monazite textures (including detrital diagenetic monazite, which prove recycling), sandstone petrology, heavy-mineral abundances, and other detrital proxies are all accounted for by the following: 1) lithic arenite is directly sourced from late Neoproterozoic metasediments in the proximal Appalachian fold and thrust belt via transverse drainages, 2) the late Neoproterozoic sediments were recycled from early Neoproterozoic, post-Grenvillian clastic sequences, 3) Cambrian quartz arenites along the Laurentian margin were recycled from Neoproterozoic sequences with local cratonic input, 4) although dominated by sediment of ultimate Grenvillian age, quartz arenites require ∼ 40% of Paleoproterozoic and Archean input, interpreted to be recycled from late Neoproterozoic to Devonian clastic sequences of the northern Appalachians and/or southern (Scottish–Irish) Caledonides in the distal reaches of a longitudinal drainage system. Ordovician to Mississippian clastic sequences and their metamorphosed equivalents in the Appalachian crystalline core were also likely sediment sources. Quartz arenite does not result from mixing of lithic arenite with other sources because of differences in textural and compositional maturity, and in heavy-mineral characteristics. Input from the Laurentian craton, commonly cited as the source for Paleoproterozoic and Archean detrital zircon in the eastern Laurentian clastic systems, is untenable here because of: 1) the presence of Paleozoic monazite derived from Appalachian Neoproterozoic and early Paleozoic metasediments, 2) abundant detrital chromite, and 3) abundant Paleozoic detrital muscovite. Multiple recycling explains all observed sedimentologic and mineralogic characteristics of the two lithic types. Incorporation of published detrital-zircon data for Paleozoic to modern clastic sequences in eastern Laurentia reveals that Grenville-age zircons experienced at least five and potentially ten recycling events since entering the clastic system in the Neoproterozoic. Recycling also explains the abundance of quartz pebbles in conglomerates of the quartz-arenite lithofacies, and the range of detrital-muscovite 40Ar/39Ar ages in quartz arenites of the Appalachian Basin.
An Investigation of Multicomponent Gas Flow in Porous Media
Authors: Azni Ahmad Shazryz , Tutolo Benjamin , Kantzas Apostolos 
Published: March 2023

AbstractThe complex gas dynamics in tight and shale reservoirs have become an important research topic in the oil and gas industry. This study proposes a steady-state flow test using adsorbing and non-adsorbing gases of single and binary gas components through tight adsorbing and non-adsorbing cores to investigate the true permeability value of its diffusion and slip counterparts.A steady-state flow permeability test was chosen to capture the complex gas dynamics in nanopore throats and the presence of organic matter. 1-D experiments in adsorbing (shale) and non-adsorbing (sandstone) cores are conducted under high overburden pressure at room temperature. The pressure difference and gas flow rates across the cores are measured. Helium (base case) is flowed, followed by adsorbing gases (N2 and CH4). This is followed by flowing gas mixtures to verify whether the single component values can be used in multicomponent systems. The results are compared to existing theoretical and analytical models.The apparent gas permeability for shale and sandstone decreases as the gas changes from non-adsorbing to adsorbing. This observation is not in line with the proposed hypothesis of the current models, where the flow mechanisms in tight and shale formations are treated like parallel resistors, where the total permeability is the addition of each component. The adsorbing gas significantly influences gas permeability when comparing the Klinkenberg plots for single and binary gas. The binary gas permeabilities skewed heavily to the gas with higher adsorbing capacity. Besides that, the adsorbing gas permanently changes the shale pore throat morphology by decreasing the pore radius, which significantly affects the flow mechanisms in shale.The study centered on the dissection of the flow mechanisms (viscous flow, surface diffusion, and Knudsen diffusion) contributing to the permeability calculations. Viscous flow dominates the more permeable porous media, while Knudsen diffusion is in the shale. Besides that, the binary gas mixture in a standard steady-state flow test in permeability estimation is introduced. The binary gas mixture in permeability measurement introduces the effect of gas flooding on the measured permeability. The more adsorbing gas actively displaces the less adsorbing gas and contributes to the surface diffusion permeability.