bluuebunny/crossref_metadata_2025_split huggingface dataset:
MgO-MgAl2O4: An Efficient Catalyst for Multicomponent Synthesis of
Substituted 4H-pyran
Authors: Dib Mustapha , Kacem Marieme , Talbi Soumaya , Ouchetto Hajiba , Ouchetto Khadija , Essoumhi Abdellatif , Hafid Abderrafia , Khouili Mostafa 
Published: June 2023

Background:
The 4H-pyran compounds are an important class of heterocyclic compounds
due to their diverse biological and pharmaceutical properties. Moreover, 4H-pyran is a crucial structural
component commonly encountered in the pharmaceutical industry. Thus, it has recently gained
significant attention from industry researchers and academic organizations. Herein, we report an efficient
and eco-friendly one-pot strategy to synthesize bioactive compounds containing 4H-pyran motifs
via a multicomponent reaction. This reaction occurs by reacting equimolar amounts of ethyl acetoacetate,
malononitrile, and substituted aldehyde under mild conditions in the presence of a solid catalyst,
MgO-MgAl2O4. This latter, was obtained by heat treatment, at 800°C, of a layered double hydroxide
with the metal cation ratio of Mg2+/Al3+ = 3:1, and it was characterized by some techniques including
XRD, TG-DTA, FT-IR and N2 adsorption-desorption. Therefore, bioactive compounds containing the
pyran unit may possess intriguing biological properties. The synthetic protocol offers advantages such
as a simple procedure, good to excellent yields, and easy catalyst separation from the reaction mixture.

Methods:
Substituted 4H-pyran derivatives were prepared by the condensation reaction of substituted
aldehydes, ethyl acetoacetate and malononitrile using MgO-MgAl2O4 catalyst under mild conditions.
This study aims to develop an efficient methodology for synthesizing 4H-pyran heterocyclic compounds
that have potential applications in biological sciences. The study utilizes MgO-MgAl2O4 as a
highly effective heterogeneous catalyst.

Results:
The present research details the synthesis of 4H-pyran bioactive compounds using sustainable
reaction conditions, which resulted in high yields and facilitated the easy separation of the catalyst
from the reaction mixture.

Conclusion:
In summary, the MgO-MgAl2O4 spinel nanostructure has been successfully prepared and
fully characterized by using different physicochemical techniques such as XRD, TG-DTA, FT-IR and
N2 adsorption-desorption. Afterwards, its catalytic activity was investigated through the one-pot condensation
of aryl aldehyde, malononitrile and ethyl acetoacetate. Moreover, it exhibits good catalytic
activity for the synthesis of 4H-pyran derivatives under green conditions. These latter have many benefits,
such as simple procedure, good to excellent yields and easy separation of the catalyst from the
reaction mixture.
Pendampingan Digitalisasi Arsip Melalui Metode In – On – In untuk Meningkatkan Kemampuan Tenaga Administrasi Sekolah (TAS) dalam Pelestarian Arsip
Authors: Isbianti Pandit , Arbaatun Latifah Nur , Bintang Eka , Nur Cahyaning Dwi , Chanabillah Nur 
Published: June 2023

Abstrak: Penelitian ini bertujuan untuk menggali proses pendampingan digitalisasi arsip berikut dampaknya bagi Tenaga Administrasi Sekolah (TAS). Tenaga administrasi sekolah bertugas memberikan layanan administrasi sekolah dalam hal urusan kepegawaian, keuangan, sarana prasarana, humas, persuratan dan kearsipan, kesiswaan, kurikulum, dan administrasi umum. Kegiatan administrasi tersebut akan bermuara pada terciptanya arsip sebagai asset sekolah yang harus dilestarikan. Sayangnya, kemampuan TAS dalam melestarikan arsip masih kurang dikarenakan ketidak sesuaian latar belakang pendidikan dengan bidang tugas dan minimnya kegiatan peningkatan kompetensi pengelolaan arsip. Sehubungan dengan hal tersebut, dilakukanlah pendampingan digitalisasi arsip melalui metode In-on_in untuk meningkatkan kemampuan TAS dalam pelestarian arsip. Penelitian ini merupakan penelitian kualitatif dengan sumber data tenaga administrasi sekolah. Hasil penelitian ini mencakup proses pendampingan yang meliputi in the job training 1, on the job training dan in the job training 2 serta dampak kegiatan pendampingan berupa meningkatnya kemampuan TAS dalam pelestarian arsip. Assistance in Archive Digitization Through The In-On-In Method to Improve The Ability of School Administration Personnel (TAS) in Archive PreservationAbstract: This study aims to explore the process of assisting archive digitization and its impact on School Administration Staff (TAS). School administration staff are tasked with providing school administrative services in terms of personnel affairs, finance, infrastructure, public relations, correspondence and archives, student affairs, curriculum, and general administration. These administrative activities will lead to the creation of archives as school assets that must be preserved. Unfortunately, TAS 'ability to preserve archives is still lacking due to the incompatibility of educational background with the field of work and the lack of activities to increase archive management competence. In connection with this, assistance was carried out on digitizing archives through the method In-on-in to improve TAS ability to preserve archives. This research is qualitative research with data sources of school administration staff. The results of this study include the mentoring process which includes in the job training 1, on the job training and in the job training 2 as well as the impact of mentoring activities in the form of increasing TAS ability to preserve archives.
Pemberdayaan Masyarakat melalui Pendidikan Nonformal di PKBM Tiara Dezzy Samarinda
Authors: Lukman Andi Ismail 
Published: June 2023

Abstrak: Penelitian ini bertujuan untuk melihat proses pemberdayaan yang dilakukan pada PKBM Tiara Dezzy. Penelitian ini menggunakan metode kualitatif dengan jenis penelitian deskriptif. Teknik pengumpulan data berupa observasi, wawancara, dan dokumentasi. Hasil dari penelitian ini, yaitu: Pertama. Tahap penyadaran tidak dilakukan oleh pihak PKBM Tiara Dezzy. Penyelenggara PKBM langsung mendata dan memanggil masyarakat untuk bergabung dan mengikuti program pemberdayaan. Kedua. Tahap transformasi pengetahuan, materi/bahan pembelajaran tidak semuanya bersifat potensi lokal. Pelaksanaan pembelajaran atau pelatihan bersifat partisipatif sehingga masyarakat turut aktif dalam pembelajaran, dan jadwal pembelajaran ditentukan sendiri oleh warga belajar. Ketiga. Tahap peningkatan pengetahuan untuk kemandirian masyarakat, warga belajar belum mandiri. Akan tetapi, terjadi perbaikan pendidikan dan perbaikan tindakan. PKBM Tiara Dezzy belum melakukan pemberdayaan secara tuntas karena hanya melakukan tahap transformasi pengetahuan. Penyelenggara PKBM memaknai pemberdayaan masyarakat sama dengan pengembangan kapasitas, padahal tidak demikian karena pengembangan kapasitas hanya bagian dari proses pemberdayaan masyarakat. Community Empowerment through Non-Formal Education in Tiara Dezzy Community Learning Center Samarinda Abstract: This study aims to see the empowerment process carried out at CLC Tiara Dezzy. This research uses qualitative method with descriptive research type. Data collection techniques were observation, interviews, and documentation. The results of this study, namely: First. The awareness stage was not carried out by CLC Tiara Dezzy. CLC organizers immediately record and call the community to join and participate in the empowerment program. Second. The transformation stage of knowledge, learning materials/materials are not all local potential. The implementation of learning or training is participatory so that the community is actively involved in learning, and the learning schedule is determined by the learning residents themselves. Third. The stage of increasing knowledge for community independence, learning residents are not yet independent. However, there has been improvement in education and improvement in action. CLC Tiara Dezzy has not done empowerment completely because it only performs the knowledge transformation stage. CLC organizers interpret community empowerment as the same as capacity building, even though this is not the case because capacity building is only part of the community empowerment process.
Pembelajaran Partisipatif Sebagai Metode dalam Meningkatkan Hasil Belajar Mahasiswa
Authors: Alisalman Muhamad 
Published: June 2023

Abstrak: Tujuan penelitian ini adalah untuk mengetahui penerapan metode pembelajaran partisipatif dalam meningkatkan hasil belajar mahasiswa Stiper Berau. Jenis Penelitian adalah penelitian tindakan kelas. Sumber data diperoleh dari, wawancara, observasi dan analisis dokumen. Tehnik analisis data menggunakan reduksi data, display data dan verifikasi data. Penerapan metode pembelajaran partisipatif dilakukan pada mata kuliah sosiologi pedesaan. Hasil penelitian menunjukkan terdapat beberapa tahapan yang dilakukan seperti, 1). Perencanaan: menyusun RPP, Silabus, materi dan bahan perkuliahan, 2). Pelaksanaan: perkenalan dosen dengan mahasiswa, penjelasan mengenai gambaran umum mata kuliah, dosen mempelajari latar belakang mahasiswa, terjadi komunikasi aktif antara dosen dengan mahasiswa, diskusi mahasiswa, dosen menjadi moderator yang mengatur jalannya diskusi, dosen melakukan konfirmasi ketika terjadi kesalahan mahasiswa dalam memahami isi materi, setiap pertemuan mahasiswa memiliki tingkat keaktifan yang tinggi, kecuali pada saat pembelajaran online, pemberian motivasi di akhir perkuliahan, 3). Penilaian: kemampuan mahasiswa meningkat (khususnya keaktifan berbicara, cara berpikir kritis, dan problem solving Participatory Learning as A Method to Increase Student Learning OutcomesAbstract: The purpose of this study was to determine the application of participatory learning methods in improving student learning outcomes of Stiper Berau. This type of research is descriptive qualitative research. Sources of data obtained from interviews, observations and document analysis. The data analysis technique uses data reduction, data display and data verification. The application of participatory learning methods is carried out in rural sociology courses. The results showed that there were several stages carried out such as, 1). Planning: preparing lesson plans, syllabus, lecture materials and materials, 2). Implementation: introduction of lecturers with students, explanation of the general description of the course, lecturers study the background of students, active communication occurs between lecturers and students, student discussions, lecturers become moderators who regulate the course of discussions, lecturers confirm when students make mistakes in understanding the content of the material , every student meeting has a high level of activity, except during online learning, giving motivation at the end of the lecture, 3). Assessment: students' abilities have increased (especially active speaking, critical thinking, and problem solving
Model Pengembangan Pendidikan Karakter untuk Meningkatkan Perilaku Positif
Authors: Purnomo Sidiq , Widodo Hendro 
Published: June 2023

Abstrak: Salah satu tantangan permasalahan sosial yang ada di masyarakat adalah kenakalan remaja. Fenomena perilaku negatif atau kenalan remaja sebenarnya dapat diminimalisir dengan adanya kerja sama dari berbagai pihak. Selama ini pendidikan karakter hanya disisipkan sebagai program tambahan di luar pendidikan Agama dan Pendidikan Kewarganegaraan. Sehingga pendidikan karakter belum mencapai yang diharapkan, terbukti masih banyak sikap dan tingkah laku para pelajar yang menunjukkan karakter yang negatif. Penelitian ini bertujuan untuk mengembangkan model pendidikan karakter yang sampai pada teknis penerapannya. Metode yang digunakan diadaptasi dari langkah pengembangan yang dikembangkan oleh Borg Gall. Prosedur pengembangan yaitu pengumpulan data, tahap perencanaan, tahap pengembangan produk awal, validasi ahli dan produk akhir. Teknik pengumpulan data wawancara, angket, observasi dan dokumentasi. Teknik analisis data yaitu analisis deskriptif kualitatif dan analisis kuantitatif. Hasil penelitian menunjukkan bahwa buku panduan yang dikembangkan berkategori layak menurut para validator. Implikasi produk dapat digunakan oleh guru sebagai acuan atau pedoman untuk menanamkan nilai karakter pada siswa secara sistematis dan terstruktur. Character Development Model for Improving Positif CharacterAbstract: One of the challenging social problems in our society is juvenile delinquency. It can be decreased with partnership from various parties. So far, character education has only been inserted as an additional program outside of religious education and citizenship education. So that character education has not reached what is expected, it is proven that there are still many attitudes and behaviors of students who show negative characters. This study aimed to develop a character education model until the implementation technique. Method used was adapted from development stage by Borg Gall. The development procedure was data collection, planning stage, initial product development stage, expert validation and final product. Data collection techniques were interviews, questionnaires, observation and documentation. Data analysis techniques were descriptive qualitative analysis and quantitative analysis. The result is the guide book has a decent category according to the experts. The implication is can be used for the teacher as guide for planting the character value to the students systematically.
Literasi Digital: Pemberdayaan Perempuan pada Kelompok Dasa Wisma di Kabupaten Banyuwangi
Authors: Susanti Lusi Dwi , Indrianti Deditiani Tri , Hilmi Muhammad Irfan , Handayani Silvia Mariah 
Published: June 2023

Abstrak: Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan bagaimana peran literasi digital dalam gerakan perempuan di kelompok Dasa Wisma di Kabupaten Banyuwangi. Penelitian ini menggunakan jenis penelitian deskriptif dengan pendekatan kualitatif. Tempat penelitian berlokasi di Dusun Balerejo, RT/RW 03/02, Desa Bumiharjo, Kecamatan Glenmore, Kabupaten Banyuwangi. Penentuan informan dari penelitian ini menggunakan teknik snowball sampling. Teknik pengumpulan data yang digunakan yaitu wawancara, observasi, dan dokumentasi. Analisis data menggunakan model Miles and Hubberman yaitu pengumpulan data, reduksi data, dan tahap penarikan kesimpulan. Hasil penelitian menunjukkan bahwa pengetahuan literasi digital anggota Dasa Wisma dilakukan dengan pendekatan secara konseptual yang berfokus pada aspek pengembangan kognitif dan sosial emosional. Pengetahuan dan kemampuan literasi digital berperan penting bagi kelompok Dasa Wisma dalam upaya memberdayakan perempuan, yakni upaya peningkatan kesejahteraan, memberikan akses agar lebih memiliki produktivitas, konsientisasi anggota, partisipasi di setiap kegiatan, dan kesetaraan dalam kekuasaan yang belum memiliki kontrol atau kuasa dalam pengambilan keputusan. Digital Literacy: Empowering Women in the Dasa Wisma Group in Banyuwangi RegencyAbstract: This research aims to identify and describe the role of digital literacy in the women's movement in the Dasa Wisma group in Banyuwangi Regency. This research uses a descriptive type of research with a qualitative approach. The research location is in Balerejo Hamlet, RT/RW 03/02, Bumiharjo Village, Glenmore District, Banyuwangi Regency. Determination of informants from this research using snowball sampling technique. Data collection techniques used are interviews, observation, and documentation. Data analysis used the Miles and Hubberman model are data collection, data reduction, and drawing conclusions. The results showed that the digital literacy knowledge of Dasa Wisma members was carried out with a conceptual approach that focused on aspects of cognitive and social emotional development. Digital literacy knowledge and skills play an important role for the Dasa Wisma group in efforts to empower women, namely efforts to improve welfare, provide more productive access, raise awareness of members, participate in every activity, and equality in power that does not have control or power in decision making.
TELEMED: Database on Evidence-Based Telemedicine in a Hospital Setting
Authors: Wagner Svendsen Ida , Kidholm Kristian 
Published: June 2023

Background
The use of telemedicine services has increased worldwide during recent years as a result of national strategies for the digitalization of health care and the COVID-19 pandemic. However, health care professionals often express uncertainty regarding the evidence and effectiveness of telemedicine interventions. Therefore, the Centre for Innovative Medical Technology at Odense University Hospital introduced the TELEMED database, an evidence-based telemedicine database.

Objective
This study aimed to ensure that hospital managers, health care professionals, and other stakeholders gain access to information about scientific studies of telemedicine interventions and their effectiveness.

Methods
The database constitutes a structured literature search in PubMed for randomized controlled trials or controlled trials on the effect of telemedicine for somatic diseases treated at hospitals. The search was conducted by staff members in the Health Technology Assessment unit at the Centre for Innovative Medical Technology. First, identified studies were sorted by screening titles and abstracts and, subsequently, by reading full-text versions. The data extracted from the studies included the setting, intervention, patient group, type of telemedicine, clinical effect, patient perception, and implementation challenges. Finally, the value of each study was assessed with respect to effectiveness.

Results
A total of 518 articles were included for data extraction and assessment. The database provides results from 22 different specialties and can be searched using the following criteria: medical specialty, country, technology, clinical effect, patient experience, and economic effect. The database serves as a platform for the dialogue with clinical departments who wish to implement telemedicine services and has a large potential for supporting the digital transformation during COVID-19 as evidence-based information on patient groups, relevant technologies, and their effect is easily accessible.

Conclusions
The TELEMED database provides an easily accessible overview of existing evidence-based telemedicine services. The database is freely available and is expected to be continuously improved and broadened over time.

Conflicts of Interest
None declared.
Graphical User Interface Development for a Hospital-Based Predictive Risk Tool: Protocol for a Co-Design Study
Authors: Marlow Nicholas , Eckert Marion , Sharplin Greg , Gwilt Ian , Carson-Chahhoud Kristin 
Published: June 2023

Background
This co-design research method details the iterative process developed to identify health professional recommendations for the graphical user interface (GUI) of an artificial intelligence (AI)–enabled risk prediction tool. Driving the decision to include a co-design process is the belief that choices regarding the aesthetic and functionality of an intervention are best made by its intended users and that engaging these users in its design will promote the tool’s adoption and use.

Objective
The aim of this research is to identify health professional design and uptake recommendations for the GUI of an AI-enabled predictive risk tool.

Methods
We will hold 3 research phases, each consisting of 2 workshops with health professionals, between mid-2023 and mid-2024. A total of 6 health professionals will be sought per workshop, resulting in a total enrollment of 36 health professionals at the conclusion of the research. A total of 7 workshop activities have been scheduled across the 3 workshops; these include context of use, notifiers, format, AI survey–Likert, prototype, AI survey–written, and testing. The first 6 of these activities will be repeated in each workshop to enable the iterative development and refinement of GUI. The last activity (testing) will be performed in the final workshop to examine health professionals’ thoughts on the final GUI iteration. Qualitative and quantitative results data will be produced from tasks in each research activity. Qualitative data will be examined through inductive thematic analysis or deductive thematic analysis in accordance with the Nonadoption, Abandonment, and Challenges to the Scale-up, Spread, and Sustainability (NASSS) framework; visual data will be examined in accordance with “framework of interactivity;” and quantitative data will be examined using descriptive statistics.

Results
Project registration with the Australia and New Zealand Clinical Trial Registry has been requested (#384098). Finalized design recommendations are expected in early to mid-2024, with a results manuscript to be submitted in mid-2024. This research method has human research ethics approval from the South Australian Department of Health and Wellbeing (#2022/HRE00131) as well as from the Human Research Ethics Committee of the University of South Australia (application ID#204143).

Conclusions
Understanding whether an intervention is needed in a particular situation is just the start; designing an intervention so that it is used within that situation is paramount. This co-design process engages end users to create a GUI that includes the aesthetic and functional details they need in a manner that aligns with their existing work practices. Indeed, interventions that fail to do this may be disliked, and at worst, they may be dangerous.

International Registered Report Identifier (IRRID)
PRR1-10.2196/47717
In Silico Analysis of Antibiotics Resistance Genes in Lactobacillus plantarum Kita-3 isolated from Halloumi Cheese
Authors: Wattimury Angelia , Suroto Dian Anggraini , Utami Tyas , Wikandari Rachma , Rahayu Endang Sutriswati 
Published: June 2023

Previous studies found that antibiotics resistance genes on plasmids in Lactobacillus make them unsafe for food purposes due to the capability of genes to transfer to pathogenic microorganisms. In contrast, Lactobacillus is widely used as a probiotic. This study assessed the antibiotics susceptibility of Lactobacillus plantarum Kita-3 isolated from Halloumi cheese using eight antibiotics. Genome sequencing was performed using the NovaSeq 6000 sequencing platform to detect the presence of antibiotics resistance genes on chromosomes and plasmids. L. plantarum Kita-3 was resistant to clindamycin, streptomycin, chloramphenicol and susceptible to tetracycline, ampicillin, kanamycin, erythromycin, ciprofloxacin. Genome sequencing of the L. plantarum Kita-3 verified the presence of the tetracycline, fluoroquinolones, β-lactamase resistance genes, and multidrug resistance efflux. Kita-3 did not have transposable elements, gene transfer agents, and plasmid-related functions. Overall, this study resulted in the antibiotics resistance profile of L. plantarumKita-3 to assess the risk of antibiotics resistance genes transfer to other bacteria. This study can provide essential data on the safe use of Lactobacillus plantarum Kita-3 as probiotics.
Analisis kadar mineral mikro tembaga dan besi pada biji durian
Authors: Lestari Ayu , Said Irwan 
Published: June 2023

This study aims to determine the levels of copper and iron contained in durian seeds, determine the levels of copper and iron using Atomic Absorption Spectrophotometer (AAS). The results showed that the analysis of the water content of durian seeds obtained 37.382%, ash content 17.782% and mass 44.835%. Analysis of the iron content measured at the copper wavelength of 248,3 nm, at the wavelength of 249,2, the results obtained respectively 49.244 ± 116.076 mg/100g for copper and 66.495± 15.753 mg/100g for iron. The results of this study are expected to be one of the alternative food ingredients that can be processed into food to meet the copper and iron substances in the body.