bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Few-shot Object Detection Algorithms: A Survey with Performance Comparison
Authors: Liu Tianying , Zhang Lu , Wang Yang , Guan Jihong , Fu Yanwei , Zhao Jiajia , Zhou Shuigeng 
Published: May 2023

The generic object detection (GOD) task has been successfully tackled by recent deep neural networks, trained by an avalanche of annotated training samples from some common classes. However, it is still non-trivial to generalize these object detectors to the novel long-tailed object classes, which have only few labeled training samples. To this end, the Few-Shot Object Detection (FSOD) has been topical recently, as it mimics the humans’ ability of
learning to learn
and intelligently transfers the learned generic object knowledge from the common heavy-tailed to the novel long-tailed object classes. Especially, the research in this emerging field has been flourishing in recent years with various benchmarks, backbones, and methodologies proposed. To review these FSOD works, there are several insightful FSOD survey articles [
58
,
59
,
74
,
78
] that systematically study and compare them as the groups of fine-tuning/transfer learning and meta-learning methods. In contrast, we review the existing FSOD algorithms from a new perspective under a new taxonomy based on their contributions, i.e., data-oriented, model-oriented, and algorithm-oriented. Thus, a comprehensive survey with performance comparison is conducted on recent achievements of FSOD. Furthermore, we also analyze the technical challenges, the merits and demerits of these methods, and envision the future directions of FSOD. Specifically, we give an overview of FSOD, including the problem definition, common datasets, and evaluation protocols. The taxonomy is then proposed that groups FSOD methods into three types. Following this taxonomy, we provide a systematic review of the advances in FSOD. Finally, further discussions on performance, challenges, and future directions are presented.
Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model Via Induction of Apoptosis
Authors: Unachukwu Uchenna , Sonett Jarrod , Woode Denzel , Shiomi Takayuki , Chada Kiran , D'Armiento Jeanine M. 
Published: May 2023

Abstract
Tuberous sclerosis complex (TSC) tumors are presently incurable despite a cytostatic response to mTOR pathway inhibition because recurrence of disease occurs after treatment is discontinued. Here, we explored the hypothesis that inhibiting tyrosine kinase activity in mesenchymal lineage-specific platelet-derived growth factor receptor β (PDGFRβ) signaling in TSC tumors is cytocidal and attenuates tumorigenesis at significantly higher levels than treatment with an mTOR inhibitor. Rapamycin-induced versus tyrosine kinase inhibitor (TKI)–induced renal angiomyolipoma (AML) and pulmonary lymphangioleiomyomatosis (LAM) tumor cells were comparatively analyzed using cell survival assays, RNA sequencing, and bioinformatics to distinguish tumoricidal mechanisms adopted by each drug type. The efficacy of imatinib therapy was validated against spontaneously developing renal cystadenomas in tuberous sclerosis Tsc2+/− mouse models (C57BL/6J mice; N = 6; 400 mg/kg/d; oral gavage) compared with Tsc2+/− mice treated with PBS (C57BL/6J mice; N = 6). Our study revealed that TKIs imatinib and nilotinib were cytocidal to both pulmonary LAM and renal AML cell cultures through the downregulation of the glycoprotein GPVI pathway and resultant disruption in mitochondrial permeability, increased cytosolic cytochrome C, and caspase 3 activation. Importantly, renal tumor growth was significantly attenuated in imatinib-treated Tsc2+/− mice compared with PBS treatment. The preclinical studies reported here provide evidence documenting the effectiveness of TKIs in limiting LAM and AML cell growth and viability with important clinical potential. Furthermore, these drugs elicit their effects by targeting a PDGF pathway-dependent apoptotic mechanism supporting the investigation of these drugs as a novel class of TSC therapeutics.
Le manuscrit Sinaï géorgien N 88
Authors: Outtier Bernard 
Published: May 2023

Résumé
On donne ici l’editio princeps du fragment de Lectionnaire géorgien N 88 du nouveau fonds découvert en 1975 au saint Monastère Sainte-Catherine du Sinaï, Égypte. Le fragment est comparé aux autres témoins géorgiens et arméniens de la liturgie de Jérusalem.
The Principal Contradictions in the History of Capitalism
Authors: Lauesen Torkil 
Published: May 2023

Abstract
This article aims to analyze the development of capitalism over a period of 500 years by the use of Mao’s concept: “The principal contradiction.” It is not an article about philosophy; the principal contradiction is presented as a working tool for analyzing and development of strategy. The article distills history into epochs characterized by changing principal contradictions. The correct identification of the principal contradiction and its interaction with secondary contradictions is the starting point of the development of a strategy, which can influence the aspect of the contradiction, in the desired direction. Finally is the relation between the contradiction in the capitalist mode of production and its expression in the changing principal contradictions discussed.
Engaging Public Health Alumni in the Tracking of Career Trends: Results From a Large-Scale Experiment on Survey Fielding Mode
Authors: Leider Jonathon P. , Rockwood Todd H. , Mastrud Heidi , Beebe Timothy J. 
Published: May 2023

Objective: We sought to understand the relative impact of fielding mode on response rate among public health alumni. Methods: As part of the 2021 Career Trends Survey of alumni from the University of Minnesota School of Public Health, we designed a fielding mode experiment to ascertain whether a paper survey, a postcard with a custom survey link (“postcard push-to-web”), a mobile telephone call or text (mobile), or an email invitation would garner the highest response rates. Invitations were randomly assigned from available contact information. Results: Of 8531 alumni invited, 1671 alumni (19.6%) completed the survey. Among the initial fielding modes, the paper survey had the highest response rate (28%), followed by mobile (19%), email (10%), and postcard push-to-web (10%). More robust recent engagement with alumni relations, paper survey invitation or mode switch, and recent graduation were all significantly associated with a higher likelihood of response. Conclusions: Paper and mobile invitations had the highest response rates to our survey among public health alumni. Findings from this fielding mode experiment are relevant to schools and programs of public health seeking to capture similar information among their alumni, especially given current trends in investment in the public health workforce.
Sense of School Belonging Among Asian American and Pacific Islander Students in U.S. High Schools: A Critical Quantitative Intersectionality Analysis
Authors: Jang Sung Tae 
Published: May 2023

Background/Context: The sense of belonging to a school is important for students, in terms of various short- and long-term developmental and academic outcomes. The inequities in the sense of school belonging among Asian American and Pacific Islander (AAPI) students may reveal a severe lack of opportunities or serious process gaps for these students. Purpose/Objective: This study investigated the nuances and complexities involved in the sense of school belonging among AAPI students in U.S. high schools, and particularly how such perceptions relate to various demographic characteristics (i.e., ethnicity, gender, socioeconomic status, and immigration status) and their intersectionalities. The study disaggregated this group into subgroups based on their ethnicities, with the aim of challenging the model minority stereotype that generalizes the experiences of AAPI students. Research Design: This study used base-year data of the High School Longitudinal Study of 2009 (HSLS:09) provided by the National Center for Education Statistics (NCES). Linear mixed-effects modeling was used to analyze a nationally representative sample. Multiple statistical interaction terms were used to identify the specific contributions (intersectionality) of AAPI students’ converging demographic characteristics. Findings/Results: This study found that the sense of school belonging was stronger for South Asian students and weaker for East Asian students when compared to the overall level, with other demographic characteristics held constant. The intersectionality model using disaggregated data revealed that the convergence of AAPI students’ ethnicity and gender creates additional nuances in their sense of school belonging, particularly for Southeast Asian and East Asian students. Conclusions/Recommendations: The findings support the call for more accurate narratives and a deeper understanding of intersectionality among AAPI students. The study suggests to policymakers and school leaders that a universal strategy for encouraging students’ sense of school belonging may not effectively address the nuanced intersectional disparities that AAPI students experience. Instead, the intersection of students’ ethnicity and gender indicates that responsive strategies that address their unique needs can better promote their perceptions of belonging to their schools.
Characteristic CT angiography findings and clinical value of catheter-related central venous thrombosis in hemodialysis patients with end-stage renal disease
Authors: Chen Yushu , Li Wanjiang , Bai Hongli , Zhang Yiteng , Lu Chunyan 
Published: May 2023

Background Central catheter-related thrombosis (CRT) is the most common catheter-related complication in patients with end-stage renal disease (ESRD) but is often underappreciated and misdiagnosed by radiologist. Purpose To find the computed tomography angiography (CTA) characteristics of central CRT, then raise the diagnosis of this disorder. Material and Methods A total of 301 eligible patients with ESRD who experienced both chest multi-phase multidetector CTA (MDCTA) and digital subtraction angiography were enrolled in the final analysis. The location, shape, and related signs of the central CRT in MDCTA images were evaluated. Independent-samples T test, chi-square test, and binary logistic regression were analyzed using SPSS software. Results In total, 166 patients were found to have CRT using MDCTA, and this was verified by DSA. Central CRT was usually irregular in the superior vena cava segment, and the angle of the contact area between central CRT and catheter was <180° (all P < 0.05). Age, collateral circulation, and venous stenosis were shown to have significant differences when compared to patients without CRT (all P < 0.05), but there were no significant differences about the sex or catheter insertion site. In addition, age and collateral circulation were the factors found to be significantly associated with thrombosis ( P < 0.05). In particular, the thrombosis was 2.213 times more likely to be found in those patients with collateral circulation (odds ratio = 2.213, 95% confidence interval = 1.236–3.961). Conclusion Chest multi-phase MDCTA can effectively reduce the missed diagnosis and misdiagnosis of central CRT. It is worth paying more attention to the central CRT especially when the collateral circulation is observed.
Medicare Benefits Schedule item numbers for transcranial magnetic stimulation (TMS): Questions arising
Authors: Pridmore Saxby , Pridmore William 
Published: May 2023

ObjectiveFour Medicare Benefits Schedule item numbers for Transcranial Magnetic Stimulation (TMS) treatment of unresponsive MDD were declared in Australia in 2021. They are accompanied by rules/conditions. The aim is to consider these rules/conditions in light of recent research and real-world experience.ConclusionsWhile evidence supports some listed rules/conditions, others lack clinical justification and deserve to be reconsidered. These include (a) ineligibility of patients who have previously received TMS, (b) a lifetime total limit of 50 treatments, (c) a second/final course being unavailable for 4 months following the completion of the first course, and (d) the second/final course being limited to 15 treatments.
Topical tacrolimus in high-risk corneal transplants
Authors: Bernardes Luís , Gil João , Costa Esmeralda , Tavares Cristina , Rosa Andreia , Quadrado Maria João , Murta Joaquim 
Published: May 2023

Purpose The purpose of this study was to assess the use of topical tacrolimus ointment in preventing rejection in high-risk corneal grafts, when added to the standard immunosuppressive regimen. Methods We conducted an observational, retrospective study using clinical data of high-risk patients subjected to penetrating keratoplasty, who were treated with topical tacrolimus ointment 0.2 mg/g twice a day plus topical dexamethasone 0.1 mg/ml 6 id and compared it with a similar control group treated with topical dexamethasone 0.1 mg/ml 6 id alone. High-risk status was attributed to patients with previous ipsilateral corneal graft failure, two or more quadrants with corneal neovascularization or an infectious or inflammatory corneal disease. Results We analysed 53 patients in the trial group versus 53 patients in the control group, with similar age, baseline diagnosis and risk factors, and median follow-up times of 30 and and 24 months, respectively. Survival analysis showed a higher graft survival rate at all follow-up periods for patients treated with topical tacrolimus ( p < 0.01). No adverse reactions were reported. Discussion This study shows that topical tacrolimus ointment increases the survival rate of the graft if added to the previous topical steroid regimen in high-risk patients. Conclusion Topical tacrolimus is safe and effective in prolonging graft survival in high-risk patients.
The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review
Authors: Kanda Yutaro , Kakiuchi Yuji , Yurube Takashi , Takeoka Yoshiki , Miyazaki Kunihiko , Kuroda Ryosuke , Kakutani Kenichiro 
Published: May 2023

Background: Primary spinal osteosarcoma is a rare and intractable disease. Although en bloc resection is favorable for longer survival, it is not always achievable. Separation surgery, a partial resection with circumferential separation to safely deliver high-dose irradiation including intensity-modulated radiation therapy (IMRT), has been recently indicated for patients with spinal cord compression secondary to solid tumor metastases. However, little evidence regarding this combination approach to spinal osteosarcoma exists. Case presentation: We report a 55-year-old male patient with a T1 tumor who underwent urgent decompression surgery for epidural spinal cord compression. Pathological findings revealed primary osteosarcoma. Separation surgery, IMRT, and adjuvant chemotherapy were applied to reduce the symptoms of epidural spinal cord compression. The patient was alive without local recurrence at the 5-year follow-up. Conclusions: Separation surgery with IMRT can be a relatively safe and effective treatment option in patients with osteosarcoma adjacent to spinal cord when en-bloc resection is challenging.
Bare Stent Fracture After TEVAR With the Modified Restrictive Bare Stent (RBS) Technique in Type B Aortic Dissections
Authors: Lescan Mario , Andic Mateja , Bonorden Constantin , Schano Julia , Hahn Julia , Schlensak Christian , Mustafi Migdat 
Published: May 2023

Purpose: The aim was to assess the mid-term aortic remodeling and bare-metal stent (BMS) integrity of the restricted bare stent (RBS) technique reconstruction in aortic dissections. Materials and Methods: This retrospective cohort study included prospectively collected patients treated with the modified RBS technique between 2017 and 2020. The preoperative, postoperative, and last follow-up computed tomographic (CT) scans were analyzed in the centerline at the mid-descending, celiac trunk (CeT), and the mid-abdominal levels for false lumen (FL) patency, aortic diameter, and true lumen (TL) diameter changes. Bare-metal stent integrity was assessed in the 3-dimensional multiplanar reformats. Results: The median follow-up of the cohort (n=17) was 26 (11, 45) months. The procedure was mainly performed with the Relay NBS endograft (15/17; 88%) + E-XL BMS (17/17; 100%). Postoperative mortality, paraplegia, stroke, renovisceral vessel loss, and type I and III endoleaks were not observed. BMS fractured in 6 patients (6/17; 36%), damaged the dissection flap in 4/17 (24%), and led to the reperfusion of the FL and re-interventions with TEVAR (4/17; 24%). Two patients without FL reperfusion showed stable CT follow-ups 13 and 17 months after the fracture diagnosis. The TL expansion was seen at all landmarks and peaked in the thoracic aorta (+10; 6, 15; p<0.001). The FL thrombosis after modified RBS was only relevant in the thoracic aorta (p<0.001) and at CeT (p=0.003). The aortic diameter was stable in the thoracic aorta and increased at distal landmarks (CeT [+5; 1, 10; p=0.001]; mid-abdominal [+3; 1, 5; p=0.004]). Conclusion: The modified RBS technique could not stop aortic growth below the diaphragm and prevent new membrane rupture due to the fractures of the BMS and consecutive flap damage with the reperfusion of the FL. Clinical Impact The treatment of complicated type B aortic dissections with TEVAR has become a standard. Particularly, patients with true lumen collapse and malperfusion may benefit from a more aggressive treatment strategy including proximal TEVAR and distal bare-metal stent implantation to re-open the true lumen and to prevent distal stent-induced new entry. However, this study reports the challenges of this approach with a high rate of bare-metal stent fractures during the follow-up. The fractures that occurred at the site of vertical nitinol bridges led to the dissection membrane ruptures and the reperfusion of the false lumen with consecutive dilatation. A close follow-up is mandatory to detect this complication and to treat the patients with TEVAR extension.
Social engagement and loneliness in school-age autistic girls and boys
Authors: Dean Michelle , Chang Ya-Chih , Shih Wendy , Orlich Felice , Kasari Connie 
Published: May 2023

Objectives: This study examines the relationship between social engagement and loneliness in female and male autistic children and adolescents in school-based social settings. Secondary aims sought to explore the emergence of loneliness across different age groups and differences in social engagement and loneliness between genders. Methods: This study conducted an analysis of previously collected data from two multi-site randomized control trials. This study included 58 autistic students (29 females, 29 males) between the ages 6 through 18 years. Female and male participants were matched on age and intelligence quotient. Concurrent mixed methods were used to examine participants’ social engagement and loneliness. Results: Findings revealed a significant relationship between joint engagement and loneliness, such that autistic students reported more loneliness when they were mutually engaged with social groups than when they were isolated or alone. Positive correlations between joint engage and loneliness were identified in elementary-age girls and secondary-age boys, suggesting that being mutually engaged with peers leads to increased loneliness. Negative correlations between parallel and loneliness identified in secondary-age boys suggested that boys in close proximity to peers felt less lonely than boys who were mutually engaged with peers. Qualitative analysis of social behaviors indicated that elementary girls and secondary boys were more likely to be mutually engaged or in close proximity to activities, but they had difficulty sustaining this engagement throughout the entire social period. Secondary girls and elementary boys, on the other hand, were more likely to be solitary and less likely to engage with peer groups. Conclusion: Study findings highlight the relationship between social engagement and loneliness in school-based autistic populations, and that more engagement itself can lead to more loneliness for younger girls and older boys. The influence of age and gender on engagement and loneliness highlights a need to tailor social interventions to leverage existing social strengths.
User experience evaluation of a 3D virtual reality educational program for illegal drug use prevention among high school students: Applying the decomposed theory of planned behavior
Authors: Guo Jong-Long , Chang Ying-Chieh , Lin Fen-He , Fan Ching-Chih , Lai Tzu-Ming , Huang Chiu-Mieh 
Published: May 2023

Objective To evaluate user acceptability of an immersive three-dimensional virtual reality program for preventing illegal drug use and identify factors associated with continuous usage intention of three-dimensional virtual reality learning among high school students based on the decomposed theory of planned behavior. Methods In this cross-sectional observational study, we developed five educational modules and serious games based on three-dimensional virtual reality technology. Ninety student-participants’ experiences were assessed by a structured questionnaire based on the decomposed theory of planned behavior variables. We applied partial least squares structural equation modeling to examine the correlates of continuous usage intention. Results The proposed model demonstrated an acceptable fit to the observed data. Eight of the 11 hypotheses based on the decomposed theory of planned behavior were supported. Continuous usage intention was significantly associated with attitudes, subjective norms, and perceived behavioral control; these variables explained 55.4% of the variance in continuous usage intention. Perceived usefulness and compatibility were significant antecedents of attitude. The significant antecedent of subjective norms was support from school staff. Self-efficacy and resource-facilitating conditions were significant antecedents of perceived behavioral control. Conclusions Our findings support the applicability of the decomposed theory of planned behavior as a framework for evaluating a three-dimensional virtual reality program for illegal drug use. We recommend that the program be included as teaching material for illegal drug prevention education in senior high schools.