bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contrast–enhanced ultrasound imaging of the optic nerve sheath diameter – a proof of concept study
Authors: Bergauer Andrej , Prosen Gregor , Kobilica Nina , Flis Vojko , Jevšek Marko , Šeruga Tomaž 
Published: February 2023

Purpose: The present proof of concept study was performed to evaluate the consistency between measurements of the optic nerve sheath taken using contrast– enhanced sonography and high– resolution magnetic resonance imaging (MRI). The main goal was to devise a novel candidate method to measure the optic nerve sheath diameter that is easy to perform, straightforward to interpret, and highly reproducible.
Methods: The approval of the National Medical Ethics Committee of the Republic of Slovenia was obtained; the study was registered under No. 30/03/12. Nine healthy young adults were examined with high–resolution MRI and contrast–enhanced ultrasound (CEUS). Measurements of the optic nerve sheath diameter were performed 3 mm behind the bulb, using both methods. The datasets were anonymized and the readers, blinded. Statistical analysis included evaluation of agreement using Bland–Altman plots. The assessment of inter– rater reliability was achieved by calculation of the intra class correlation coefficient.
Results: Bland–Altman plots showed favorable overall agreement between both methods, with clinically acceptable limits of agreement. The intra class correlation coefficient calculated for both methods suggests that the CEUS method was at least as reproducible as high–resolution MRI.
Conclusion: The described method, using CEUS to measure the optic nerve sheath diameter, facilitates the identification of the surrounding anatomy. When CEUS is employed, the measurement points can be easily and reliably set, and retro bulbar artifacts are less confounding. Based on results from a relatively small sample, this method seems to be comparable with high–resolution MRI. Evaluation of the method on a larger sample of healthy subjects and patients with increased intracranial pressure is needed.
Assessment of left ventricular impairment by calculating left ventricular impairment index using doppler echocardiography in chronic heart failure patients
Authors: Krajnc Igor , Sinkovič Andreja 
Published: February 2023

Purpose: In order to assess global left ventricular impairment in chronic heart failure (HF) patients, it is necessary to consider both functional and structural changes of the left ventricle (LV), in particular, stroke volume (SV) and left ventricular end-diastolic diameter (LVEDD). Based on SV as a marker of LV function, LVEDD as a simple indicator of structural LV changes, and height of an individual patient (H), the left ventricular impairment index (iLVI) can be calculated. The purpose of this study was to assess the diagnostic value of iLVI in chronic HF patients.
Methods: This prospective study included a total of 50 chronic HF patients and 50 healthy individuals, whounderwent standard two-dimensional echocardiography. The iLVI was calculated according to the formula: iLVI = SV x H / LVEDD2 (mL/cm). Results:The iLVI accurately separated healthy subjects from patients (AUC = 0.989), with the highest sensitivity and specificity for proper identification of HF (96.0% each),in comparison with ejection fraction (EF), stroke volume index (SVI), and SV/H. The iLVI effect was strong (Cohen’s d=3.2), exceeding that of EF, SVI, and SV/H.
Conclusion: The study concluded that the iLVI, which can be readily calculated, represents an excellent clinical marker for global functional and/or structural LV impairment in chronic HF patients.
A Novel Capacitive Method for Urodynamic Measurements That is Suitable for Home Use
Authors: Nikolić Gregor , But Igor , Stožer Andraž , Kramberger Iztok 
Published: February 2023

Purpose: Urinary incontinence is highly prevalent in both women and men. Urodynamic testing is essential for diagnosis, but a gap exists in the usefulness of simple assessments that do not provide sufficient data, and devices that provide the necessary data, but are used primarily in clinics and clinical trials. This study considered the existing methods of urodynamics testing and developed a device that was both effective and suitable for home use.
Methods: A review of existing urodynamic methods led to development of a capacitive device. We created a device with sensor electrodes placed on the outside of a specimen container. The functionality of the electrodes and performance of the novel capacitive device were compared with that of a gravimetric device (Dorado KT, Laborie Medical Technologies, Mississauga, ON, Canada) used at the University Clinical Center, Maribor.
Results: Measurements of fluid volume (p = 0.936), maximum (p = 0.327), and mean (p = 0.136) flow observed with the two devices were not significantly different. Graphical analysis of collected volumes and flow variation over time show a high degree of overlap.
Conclusion: Compared with previously developed urodynamics testing devices, the capacitance method and the performance of this device represent an advance. The precision of the measurements needs improvement and did not fully address the recommendations of the International Continence Society, but he use of additional sensor electrodes is expected to improve performance. Extending the functionality as a standalone capacitive device for home use and upgrading with wireless access by mobile systems would allow for additional benefits beyond current voiding diaries.
Percutaneous balloon aortic valvuloplasty: palliative treatment for inoperable patients?
Authors: Dovč Klemen , Markota Andrej , Kanič Vojko , Bombek Mirko , Prosen Gregor 
Published: February 2023

Purpose: The number of elderly patients with severe aortic stenosis and comorbidities is increasing in the aging populations of “developed” countries. Unacceptably high perioperative mortality and morbidity makes the decision to undertake surgical aortic valve replacement in this group of patients difficult and unlikely. Development of less invasive procedures such as balloon aortic valvuloplasty and transcatheter aortic valve replacement is emerging as another treatment option.
Case report: A 84-year-old female with previous left-sided hemiparesis after stroke and severe aortic stenosis presented with pulmonary edema to our institution. Non-invasive ventilation and inotropic support were unsuccessful. Balloon aortic valvuloplasty was done as as emergency procedure and she improved immediately. She was discharged after 25 days of inhospital treatment. She died 8 weeks later of unrelated reasons (infected decubitus and sepsis).
Conclusion: Balloon aortic valvoluplasty might be used as temporary and interim therapeutical options for patients with severe aortic stenosis and acute left ventricular failure who have unacceptably high risks when aortic valve replacement or emergency transcatheter aortic valve implantation is considered. Balloon aortic valvuloplasty may be used as a bridge to both procedures.
Arthroscopic anatomy and pathoanatomy of anterior cruciate ligament ruptures: clinical study with 94 patients
Authors: Hussein Mohsen , Čretnik Andrej , Dinevski Dejan , Rupreht Mitja , Vogrin Matjaž 
Published: February 2023

Purpose: To arthroscopically evaluate the size variability of the Anterior cruciate ligament (ACL) insertion sites and to determine whether there are variations in rupture patterns of the two ACL bundles.
Material and Methods: Ninetyfour patients undergoing ACL reconstruction between June 2008 and June 2009 were included inour study. The average age of the patients was 26.7 ± 8.3 years (range, 16–48 years). Only patients with an ACL rupture less than 120 days old were included as unpublished data revealed difficulty in distinguishing between AM and PL bundles in older ACL ruptures.
Results: The femoral ACL insertion site length ranged from 11 to 20 mm (15.9 ± 2.2). On the tibial side, the length of the tibial ACL insertion site ranged from 9 to 20 mm (16.0 ± 2.1). On the femoral side, the width of the ACL insertion site ranged from 6 to 11 mm (8.3 ± 1.2). On the tibial side, the width of the entire ACL insertion site ranged from 6 to 12 mm (8.7 ± 1.1). The most frequent injury pattern was found to be the proximal rupture of both bundles; seen in 74 patients (78.7%).
Conclusion: Both hypotheses were confirmed, and this may be clinically relevant in anatomic ACL reconstruction.
The outcome of cataract surgery in eyes with end–stage glaucoma
Authors: Gračner Tomaž , Pahor Dušica 
Published: February 2023

Purpose: To evaluate the outcome of phacoemulsification and intraocular lens implantation (PHACO IOL) in eyes with end–stage glaucoma.
Methods: Eighteen eyes of 18 patients with end–stage glaucoma in which PHACO IOL was performed were included in this prospective clinical study. Intraocular pressure (IOP) was measured before and 1 week, and 1, 3, 6, and 12 months after PHACO IOL. The best corrected visual acuity (BCVA), the number of antiglaucoma medications and the visual field (VF) test results before PHACO IOL and at the end of follow–up were evaluated.
Results: The follow–up period after PHACO IOL was 12 months for all eyes. The mean IOP before surgery was 13.5 mmHg (SD 2.6). There were no differences between the mean IOP measurements before and after surgery during the entire follow– up period (P>0.05). The mean preoperative BCVA was 0.65 (SD 0.3) logMAR, improving to a mean of 0.19 (SD 0.1) logMAR postoperatively (P<0.0001). The mean number of antiglaucoma medications before surgery was 1.8 (SD 1.4), and it was 2.0 (SD 1.3) postoperatively (P=0.104). The mean value of the mean deviation in 7 eyes on automated perimetry was –23.57 dB (SD 3.9) preoperatively and –22.87 dB (SD 4.1) postoperatively (P=0.105). The mean VF island in 11 eyes on Goldmann perimetry was 17.0° (SD 7.2) preoperatively, improving to 20.4° (SD 9.0) postoperatively (P=0.033).
Conclusion: PHACO IOL in eyes with end–stage glaucoma resulted in a stable IOP and a significantly improved BCVA without worsening of the VF.
Detection of vkorc1 polymorphism: comparison of polymerase chain reaction/restriction fragment length polymorphism (pcr + rflp) with allele–specific polymerase chain reaction
Authors: Stangler Herodež Špela , Stankovič Nastja , Zagradišnik Boris , Erjavec Škerget Alenka , Kokalj Vokač Nadja 
Published: February 2023

Purpose: The VKORC1 polymorphism is an important genetic factor affecting warfarin dose requirement. Patients require different warfarin doses in order to achieve the target therapeutic anticoagulation. The aim of our study was to determine the frequency of single nucleotide polymorphisms (SNP) in the VKORC1 gene in the general population, using a simple, rapid, and economical method.
Methods: For genotyping, the restriction fragment length polymorphism (RFLP) of polymerase chain reaction (PCR)–amplified DNA was used and compared to allele– specific polymerase chain reaction. We genotyped 441 DNA samples obtained from the healthy general population in North–Eastern Slovenia. Genotypes for the tested group were evaluated to determine whether the population followed the Hardy–Weinberg equilibrium. The genotypes and allele frequencies were calculated.
Results: The results obtained using the allele–specific polymerase chain reaction were consistent with those obtained using the PCR + RFLP method. The G allele frequency (0.62) was higher than the A allele frequency (0.38) in the general population from North–Eastern Slovenia.
Conclusions: The PCR+RFLP method involved additional manipulation of the PCR products at the expense of analysis time, consumption of reagents and equipment. The allele–specific polymerase chain reaction was a simple and rapid method for the detection of SNP in the VKORC1 gene, and is available in any laboratory with the minimum of equipment and reagents required.
Pengembangan Kawasan Wisata Alam Berbasis Partisipasi Masyarakat (Studi Kasus Air Terjun Jagir Desa Kampunganyar Kabupaten Banyuwangi)
Authors: Krismawati Piping Dwi , Hayati Nunung Nuring , Alfiah Rindang 
Published: February 2023

Air Terjun Jagir adalah wisata alam yang berada di Desa Kampunganyar, Kecamatan Glagah. Kabupaten Banyuwangi, Provinsi Jawa Timur. Kawasan wisata alam Air Terjun Jagir menjadi destinasi pilihan wisatawan yang berkunjung ke Kabupaten Banyuwangi. Namun pada kondisi eksistingnya, dengan jumlah pengunjung yang banyak wisata Air Terjun Jagir tidak diimbangi dengan fasilitas penunjang wisata yang sesuai. Dalam hal pengembangan wisata sebagian masyarakat sudah mengetahui mengenai pengembangan wisata dan menanggapi secara baik, namun masih banyak juga masyarakat yang belum mengetahui bahkan tidak berpartisipasi terhadap wisata alam Air Terjun Jagir. Penelitian ini memiliki tujuan untuk mengetahui faktor penentu pengembangan kawasan wisata alam Air Terjun Jagir, mengetahui bentuk partisipasi masyarakat Desa Kampunganyar, dan merumuskan arahan pengembangan kawasan wisata alam Air Terjun Jagir berdasarkan partisipasi masyarakat. Penelitian ini menggunakan 2 metode analisis data untuk mencapai tujuan yang diinginkan. Pertama, menggunakan metode Analisis Delphi untuk menentukan faktor-faktor penentu pengembangan Air Terjun Jagir. Kedua, menggunakan Analisis Deskriptif untuk menentukan bentuk-bentuk partisipasi masyarakat Desa Kampunganyar dan untuk menentukan arahan pengembangan kawasan wisata alam Air Terjun Jagir. Hasil penelitian ini yaitu terdapat 6 faktor penentu yang mempengaruhi pengembangan Air Terjun Jagir. Sedangkan bentuk partisipasi yang diberikan masyarakat Desa Kampunganyar terbanyak yaitu partisipasi tenaga dan tingkat partisipasinya berada di tingkat consultation yang tergolong dalam Tokenis. Serta arahan pengembangannya ditentukan berdasarkan faktor attraction, accessibility, amenities, ancillary, sumberdaya manusia, dan lingkungan yang disesuiakan dengan kebijakan atau teori yang berkaitan.
MATRIK TRANSFORMASI PADA RUANG BARISAN ORLICZ
Authors: Haryadi Haryadi 
Published: February 2023

In this study will be characterized a matrix that maps the space of the Orlicz sequence space to the space of the bounded sequence and the convergence sequence. This study is carried out by generalized the matrix mapping on lp space, 1<=p<\infty, to the Orlicz sequence space. This results establishes a necessary and sufficient conditions for a matrix that maps the Orlicz sequence space to the bounded sequence space, convergence to sequence space and the convergence sequence space.
Indeks Kepuasan Masyarakat (IKM) Pada Mal Pelayanan Publik Kota Banjarbaru Tahun 2022
Authors: Rizky Subhan Rizky Subhan 
Published: February 2023

In this study, the Banjarbaru City Public Service Mall will be the object of this study. The research aims to analyze the community satisfaction index (IKM). Provisions regarding the community satisfaction index (IKM), according to the Minister of Administrative Reform where there is a decree number 14 of 2017 concerning general guidelines for compiling the community satisfaction index for government agency service units. The approach used in this study is a quantitative method approach, with measurements using a Likert Scale. The sample used in this study was 150 respondents, with the sampling technique of probability sampling. Data analysis techniques in this study were analyzed beforehand by testing the validity and reliability tests then processing the data with a data tabulation system to draw conclusions about the community satisfaction index. The overall community satisfaction index for all indicators obtained an IKM value of 3.94 and an IKM conversion value of 78.8 which is in the category of service quality B and is in the good performance category. This shows that the services provided by public service mall officers are carried out properly. So that people are satisfied with the performance of the Banjarbaru city public service mall. Keywords: Public Service, Community Satisfaction, Community Satisfaction Index, Public Service Mall
STRYCHNOS SPINOSA LAM: COMPREHENSIVE REVIEW ON ITS MEDICINAL AND NUTRITIONAL USES.
Authors: Tittikpina Nassifatou Koko , Atakpama Wouyo , Hoekou Yao , Diop Yerim Mbagnick , Batawila Komlan , Akpagana Komlan 
Published: February 2023

Background: Most of the people living in developing countries rely on local remedies from traditional medicines to take care of their healthcare needs. In recent years, the use of medicinal plants increased considerably. Consequently, studies on medicinal plants are necessary to produce more effective drugs with fewer side-effects. This work aims to compile the dispersal data on Strychnos spinosa Lam., a medicinal plant with great therapeutic potential in traditional medicine, on its ethnobotanical uses, chemical compounds, as well as its pharmacological and nutritional effects.
Material and Methods: To achieve the aforementioned aim, electronic databases such as Pubmed, Science Direct, Google scholar, Scopus and SciFinder were scanned.
Results: Literature survey revealed that S. spinosa is used in the treatment of microbial infections, malaria, trypanosomiasis, intestinal worms, tuberculosis, infertility, gastrointestinal disorders, snake bite, hypertension, and diabetes mellitus among other ailments. The plant is also used as food material. S. spinosa contains many chemical compounds, such as alkaloids, terpenes, sterols, fatty acids, flavonoids, saponin, and others. The fruits are a source of important nutrients such as carbohydrates, sugars, proteins, vitamins and fibres. Experimental studies have shown numerous pharmacological properties, including antimicrobial, antiplasmodial, anti-trypanosomal, anti-leishmanial, anti-nematicidal, anti-inflammatory, anti-oxidant, antidiabetic and other activities.
Conclusion: This review article provides comprehensive information on S. spinosa and its various extracts. Due to the promising effects of the plant extracts on various diseases and its nutritional values, there is a need for toxicity studies and clinical trials to assess the effects of its identified bioactive compounds.
Experiment and Simulation Analysis of the Vibration Response of the Rotor-bearing System
Authors: Qian Bing , Ran Yinkang , Ding Qiang , Sun Weipeng , Ma Chenyuan 
Published: February 2023

Abstract
The unbalanced mass of the rotor-bearing system may cause abnormal vibration of the rotor-bearing system, which may affect the safe operation of the system in severe cases. In this paper, the rotor-bearing system fault simulation test bench and MADYN 2000 were used to test and simulate the single-disk shafting rotor mass unbalance fault. The research analyzes the influence of speed, unbalanced mass, support stiffness, and phase of unbalanced mass on the vibration response of the rotor-bearing system. The results show that when the speed is higher than the first-order critical speed, after the rotor starts, the amplitude gradually increases with the speed, reaches the peak at the first-order critical speed, and then gradually decreases to a stable value. Due to the anisotropy of the bearing support, the rotor has different amplitudes in each direction, but the change trend is the same, the support stiffness is small, and the stable value is reached faster. When the rotation speed and the unbalanced mass phase are the same, the rotor amplitude and the rotor unbalanced mass have a linear relationship. When the speed and unbalanced mass are the same, the rotor amplitude fluctuates with the change of the loading phase, and the fluctuation period is π. The research results have certain reference significance for the fault diagnosis and dynamic characteristics analysis of the unbalanced response of the rotor-bearing system.
A Neuromechanical Control Model For Rhythmic and Discrete Movements Based on Central Pattern Generator (CPG)
Authors: Nia Nafiseh Ghaffar , Bahrami Fariba , Kaplanoglu Erkan , Nasab Ahad 
Published: February 2023

Abstract

Movement is one of the essential characteristics of living beings. Despite the diversity of animal species and the apparent differences, standard features exist between their movement systems that follow a particular pattern. The movements can mainly be divided into discrete and rhythmic categories controlled by the central nervous system. Scientists usually consider these two types of motion separately in the control system and use different methods and resources to produce and model them. Proposing a unified and comprehensive model for generating and controlling rhythmic and discrete movement with the same control system is more valuable, albeit challenging. The present study provides a single neuromechanical control model for producing and controlling rhythmic and discrete movements. This model consists of a neural oscillator, the central pattern generator (CPG), coupled with inhibitory and excitatory paths to drive the flexor and extensor muscles. The computational model of this study follows the Hodgkin-Huxley (HH) equations. The structure of the model, the factors involved in creating the motion, and the oscillation were analyzed in great detail. It was found that supraspinal input and motor neuron feedback, as the motor control parameters, play an essential role in the activity and directly impact the production and control of rhythmic and discrete movements. According to these parameters, a neuromechanical model that can create both rhythmic and discrete movement is presented. The model also addresses the switching mechanism between rhythmic and discrete states.
Klebsiella michiganensis: A nitrogen-fixing endohyphal bacterium from Ustilago maydis
Authors: Liang Pengyu , Jiang Jianwei , Sun Zhengxiang , Li Yanyan , Yang Chunlei , Zhou Yi 
Published: February 2023

Abstract

Ustilago maydis is a pathogenic fungus in Basidiomycota causing corn smut disease. A strain of U. maydis YZZF202006 was isolated from the tumor of corn smut collected from Jingzhou city in China. The intracellular bacteria were confirmed inner hyphal of the strain YZZF202006 by PCR amplification and fluorescence in situ hybridization (FISH) and SYTO-9. An endohyphal bacterium YZUMF202001 was isolated from the protoplasts of the strain YZZF202006. It was gram-negative, short rod-shaped with smooth light yellow colony. The endohyphal bacterium was genomic evidenced as Klebsiella michiganensis on the basis of average nucleotide identity (ANI) analysis and the phylogram. And then K. michiganensis was GFP-Labeled and reintroduced into U. maydis, which confirmed the bacterium can live in hpyphal of U.maydis. The bacterium can grow on N-free culture media. Its nitrogenase activity was reached av. 646.25 ± 38.61 nmol·mL−1·h−1 C2H4 by acetylene reduction assay. A cluster of nitrogen fixation genes (nifJHDKTXENXUSVWZMFLABQ) was found from its genome. The endohyphal K. michiganensis may play an important role to help nitrogen fixation for fungi in the future.