bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of leukapheresis and leukapheresis with additional cytoreduction in acute leukemia with hyperleukocytosis
Authors: ALP KIRKIZLAR Tuğcan , DEMİR Ahmet Muzaffer 
Published: July 2023

Background Hyperleukocytosis is a high-mortality emergency that must be diagnosed and treated promptly. The treatment options are low-dose cytosine arabinoside, hydroxyurea, steroids and leukapheresis. The risks and benefits of leukapheresis and leukapheresis with cytoreductive drugs in hyperleukocytosis are unclear. Therefore, we aimed to evaluate the efficacy of leukapheresis and the effect of adding cytoreductive drugs to leukapheresis in reducing leukocyte count and mortality in our patients.
Material and Methods Thirty-four adult patients with acute leukaemia who underwent leukapheresis were included in this retrospective study.
Results The median age was 66.5 years old, and 88.2% of the patients were acute myeloid leukaemia. The total number of leukapheresis was 69 cycles, and the median number of the procedure was 2. The most common symptoms were associated with the pulmonary system (67.6%). The median follow-up was 17.5 days. The mean reduction of leukocyte count was 69,112/mm3, and the efficacy of leukapheresis was 40.9%. The decrease in leukocyte and platelet counts was statistically significant when compared before and after leukapheresis. The mortality rate was 76.5% during hospitalization. While 24 patients received concomitant cytoreductive drugs with leukapheresis, ten did not. There was no statistically significant difference between these groups regarding reducing leukocyte count, efficiency of leukapheresis and mortality (p values 0.857, 0.562 and 0.553).
Conclusions In our study, we showed the efficacy of leukapheresis in hyperleukocytosis but failed to show any difference in leukocyte reduction or mortality with additional cytoreductive drugs. Leukapheresis with concomitant cytoreduction does not abolish or increase mortality.
The Analysis Influence Economy Growth, Labor Education Level and Interest Rate on Investment in Maluku Province
Authors: Leasiwal Teddy Christianto , Honoeboen Bin Raudha A. 
Published: July 2023

Investment in Maluku from year to year grows slowly, compared to its potential. To overcome the obstacles that hinder investment, the policies established by the regional government include accelerating the development and preparation of infrastructure supporting investment activities, creating a more conducive investment and business climate in the regions, developing human resources, both government and business actors in the regions. There are three variables, namely Economic Growth, Education and Interest Rates . The method of analysis used is multiple linear regression analysis. On result regression seen that the growth variable economy have connection positive , this is indicated by score coefficient as big as 5.363299 and has a significant influence significant to investment with a probability value of 0.0005. There is a positive relationship between the education level of the workforce and the level of investment with a coefficient value of 0.160310 . and very significant with a probability value of 0.0001. The interest rate has a negative effect on investment, with a coefficient value of -1.333418 meaning that an increase in the interest rate by 1% will also reduce investment by -1.333418 although the coefficient value is not significant.
Vol. 4, N.º 2, Jul-Dez 2023 - "Inovações com impacto na Radiologia"
Authors: Editorial Conselho 
Published: July 2023

Sétima publicação da ROENTGEN - Revista Científica das Técnicas Radiológicas, com especial destaque para a temática "Inovações com impacto na Radiologia".
Neste número da ROENTGEN pretendemos explorar o tema das inovações na Radiologia e os efeitos dessas transformações na sociedade, na saúde e, mais importante ainda, na qualidade de vida dos pacientes.
EDUKASI MASYARAKAT TENTANG GIZI SEIMBANG DAN PERILAKU HIDUP SEHAT (PHBS) SEBAGAI UPAYA PENCEGAHAN PENYAKIT DI RW 01 KELURAHAN KOTA BAMBU UTARA JAKARTA BARAT
Authors: Abna Inherni Marti , Amir Mellova , Rahayu Sri Teguh , Marseli Zahra , Alam Raihaque Fahd , Husna Bella Nur , Mursalina Diana , Wetenrisui Walunari , Prasetyo Jesisca Endah Artati 
Published: July 2023

Indonesia sebagai negara berkembang menghadapi berbagai masalah penyakit menular dan penyakit tidak menular sehingga menurunkan kualitas kesehatan masyarakat. Penyakit menular (PM) maupun penyakit tidak menular (PTM) dapat dicegah dengan menerapkan pola gizi seimbang dan membiasakan perilaku hidup bersih dan sehat (PHBS) di masyarakat. Hal ini mendorong dilaksanakannya pengabdian masyarakat di RW 01 Kelurahan Kota Bambu Utara Jakarta Barat dengan tujuan untuk meningkatkan kesadaran masyarakat tentang pentingnya penerapan pola gizi seimbang dan perilaku hidup bersih dan sehat (PHBS), agar masyarakat mendapatkan kualitas kesehatan yang lebih baik. Metode yang digunakan dalam program pengabdian masyarakat ini adalah memberikan edukasi secara langsung dengan penyuluhan metoda ceramah, turun ke rumah-rumah warga dan metode edukasi tidak langsung dengan penyampaian informasi melalui media sosial. Hasil dari kegiatan pengabdian masyarakat ini adalah bertambahnya pemahaman masyarakat tentang pentingnya pola gizi seimbang dan perilaku hidup bersih dan sehat (PHBS) .Kata Kunci: gizi, penyakit,penyuluhan
From Entertainment to Agnoisation: Social Media Impact on Students’ Life during COVID 19 Pandemic
Authors: Ahmed Fahad , Siddiqui Danish , Khan Atiya , Khan Danish , Akhter Javeria , Parvez Aithisham 
Published: July 2023

Purpose: According to “Global Statshot Report” indicating 4.65 billion Social Media (SM) consumers in Oct 2021, its numbers present almost 57.6 percent of the world population. SM scrolling, video calling texting, browsing on Google, and other internet surfing are causing numerous health issues like headache, earache, neck pain, tinnitus, painful fingers, fatigue, eye symptoms, morning temporary state, restlessness, and sleep disturbances developed in users. With this concept, this study aims to find out the association of SM effects on student’s physical health and cognitive skills. Excessive use of SM causes negative effects on both cognitive skills and physical health.
Methodology: This analytical cross-sectional study has been conducted at Indus University of Health and Science, Korangi Crossing, Karachi over 01-year timeline (Feb 2021 to Jan 2022). The sample size of 167-170 was targeted on both male and female age group (16 to 35) who were active user of social media and electronic gadgets Any discipline (nursing, allied health, biosciences, medical technology, etc.) enrolled in this study. Any person with a mental and physical disorder or under psychological therapy was excluded beforehand.
Findings: Excessive use of SM affects cognitive skills, Forgetfulness, Distractibility and False Triggering mean score was high in the second group of high users. Statistical associations were found between Forgetfulness and Distractibility in both groups.
Recommendations: This study will provide awareness to students and society regarding the negative effects of SM on health.
The Climate Policy of the Member States of the Eurasian Economic Union: Synchronizing with the Global Climate Change Agenda
Authors: Zhiltsov Sergey , Murashko Marina 
Published: July 2023

The paper deals with the climate agenda in the Eurasian Economic Union. Particularly, it analyzes the current stage of implementation of green finance principles in the member states of the EAEU. In the article, the authors identify the key problems for the social and economic development of the member states in the context of the global environmental transformation and examine most relevant policy documents to address climate challenges. At present, all EAEU member states are committed to the Paris Agreement. They are developing framework for sustainable finance system at the national levels and made efforts to introduce green finance principles within the organization. However, for the most part, little progress has been made. The authors stress that different timelines and trajectories will hinder the EAEU to achieve carbon neutrality, so, in the first place, the issue of the contingency of national climate policies within the Union should be addressed.

Received: 8 March 2023 | Revised: 25 June 2023 | Accepted: 20 July 2023

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
Data available on request from the corresponding author upon reasonable request.
The effect of trehalose administration on the serum expression levels of microRNAs associated with lipid metabolism and autophagy process in patients with myocardial infarction - the post-hoc analysis of the TREAT-IR trial.
Authors: Ganjali Shiva , Mansouri Atena , Reiner Željko , Jamialahmadi Tannaz , Moallem Seyed Adel , Salehabadi Sepideh , Banach Maciej , Sahebkar Amirhossein 
Published: July 2023

IntroductionThis study aimed to evaluate the TRE-induced changes in the serum expression levels of miRNAs associated with lipids metabolism and autophagy process in MI patients to assess the potential protective effects of TRE in these patients.Material and methodsThis post hoc investigation was performed on serum samples obtained from a pilot randomized, double blind, placebo-controlled clinical trial that recruited 14 men (aged 18-80) who had MI and systemic inflammation. The patients were randomized in a 2:1 ratio to either TRE (15 g/week, intravenous (IV) ad-ministration) (N=10) or placebo groups (equal volume of saline 0.9 %) (N=4) for a period of 12 weeks. To measure the relative serum expression levels of miRNA-155, miRNA-221, and miRNA-33, the SYBR Green qPCR method was used.ResultsmiRNA-155 showed significantly higher serum expression levels in the TRE group (2.772±0.73; P=0.009) when compared to the placebo group. Also, significant reductions in miRNA-155 (0.171±0.03; P=0.016), miRNA-221 (0.116±0.07; P=0.013), and miRNA-33a (0.076±0.07; P=0.025) were observed in the placebo group at the end of the study. Nevertheless, the reduction (normalized to the baseline) of the serum expres-sion levels of miRNA-221 (FC:0.87±0.20 vs FC:0.18±0.08; P=0.009) and miRNA-33a (FC:0.73±0.22 vs FC:0.13±0.08; P=0.025) were significantly less in TRE group than in the placebo group.ConclusionsIV TRE administration did not reduce the expression of miRNA-221 and miRNA33a as much as placebo. Keeping a steady state of the serum expression levels of these miRNAs associated with lipoproteins metabolism and autophagy in the TRE group might have protective effects in patients with MI.
Relationship of Blood Groups to the Incidence of Hyperuricemia and Hyperglycemia
Authors: Gata Abbas Mehsen , Kasim Sumayah Faruq , Mohammed Sarah Mohssen , Samanje Jaleel 
Published: July 2023

Several experiments have been carried out to estimate the relationship between blood grouping types and the occurrence of diabetes, but not hyperuricemia. The effects of the potential correlation between the ABO blood groups and the incidence of these cases have been recorded in this study. The aim of this study is to see whether there is a connection between ABO blood groups and the occurrence of hyperuricemia and hyperglycemia among samples of Iraqi patients. This research was carried out in Educational Laboratories/Medical City (Baghdad Governorate). The research was carried out of the ABO blood with age range (40-70) years, ABO blood group was performed by the sliding method, while uric acid and glucose blood levels were measured by utilizing an enzymatic procedure. There are significant differences in the levels of uric acid between blood groups (A and AB) and blood groups (A and O), while the levels of serum glucose were highly significant between blood groups (B and AB) and blood groups (AB and O). It is concluded that blood groups type AB could be the most vulnerable to the occurrence of hyperuricemia and hyperglycemia. However, further investigations with consideration to Rhesus factor Rh are required.
The Design Idea and its Application in the Inner Space (Refreshments Shops as Sample)
Authors: Ghazal Naderah Abdul Razzaq 
Published: July 2023

The inner or architect faces difficulty in choosing his applicable design, so that the research presents a study based on scientific and practical components to find out a design idea as an objective study and the mechanisms of application by utilizing modern technology and the products of the digital world to achieve a sustainable and balanced environment participates in upgrading the inner designs so it comes with the concept of the design idea and means of cognitive processing that take part in its application in real life to reach the title of the research “The design idea and its application in the inner space ‘’ the study as a necessity resulted from a need to increase design awareness in finding out a link between the application of the design idea and precept it.
The research problem ‘’ does the design idea and its application in the inner space (Refreshments Shops) as a sample have sensible and perception values participate in achieving connection with the recipient?
The target of the research aims at uncovering the role of the design idea and its application in the inner space and its importance in being discussed in a study resulted from a necessity to improve the level of inner designs of refreshments shops in the city of Baghdad, the objective limits ‘’The design idea and its application in the inner space’’, and the place and time limits of it from Al Fiqma refreshments shop at Al Karrada \ Al Fiqma refreshments shop at Al Sidiyah from (1983-2013), insure the conceptual framework the design idea and perception processing to apply the design idea.
There are a number of indications resulted from the research and adopted in the samples analyzing form and discussing the previous studies close to the subject of the research.
The research methodology and procedures come to reach the results and conclusions and lead to a number of conceptualization pillars.
Comparison between Sevoflurane and Isoflurane Effects on Hemodynamic Status
Authors: Hama Adel Amen 
Published: July 2023

Back ground: Volatile anaesthetics are known to cause hypotension because of its effects on the central nervous system and autonomic nervous system, on the myocardium as well as its direct action on vascular smooth muscle.
Aim of study: is to compare between sevoflurane and isoflurane effects on pulse rate and mean blood pressure during general anaesthesia.
Patients and methods: this prospective study was carried out at Al-Hilla Teaching Hospital/Babylon as well as Balad General Hospital/Salah Al-Din, from 2nd (March) 2021-20th (May) 2021. Thirty patients between the ages 7- 68 years were enrolled in this study, 13 Male and 17 females. All patients fasted for 8-10 hours before proposed time of surgery. In all selected patients, pulse rate and mean blood pressure was recorded at baseline, at intubation at (5 Minute), (10 Minute), (15 Minute), (20 Minute), (25 Minute), (30Minute), (40 Minute) of the time of operation, extubation, and recovery.
Results: showed that non-significant differences between inhalation agent (sevoflurane and isoflurane) and hemodynamic status (pulse rate and Mean blood pressure) at different time. The Groups according to their gender, showed high percentage of 38.5% in males at age group of 36-50. While 50.0% of females at age group 21-35 years. The most patients which received Isoflurane as inhalational agent were female groups (52.9%) versus (46.2%) for male groups, the female group which received Sevoflurane inhalational agent were (47.1%) versus (53.8%) for male groups.
Conclusion: it conclude that the sevoflurane and isoflurane is more anesthetic stable gas on heart rate and mean blood pressure.
O lúdico no quilombo: um ensaio fotoetnográfico sobre a situação do brincar no Quilombo Urbano da Liberdade
Authors: Santos Camila Andrade dos 
Published: July 2023

As diferenças relacionadas a fatores de classe e raciais, as desigualdades e formas de exclusão também são observadas em espaços e equipamentos públicos lúdicos dedicados às infâncias na cidade de São Luís. No quilombo da Liberdade, esses ambientes refletem o descaso do poder público: são centralizados, não sendo facilmente acessados ao conjunto da população do Bairro, encontram-se em péssimas condições de manutenção e diferem-se estética e formalmente dos espaços lúdicos das áreas com metros quadrado mais caros da cidade. Este ensaio fotoetnográfico é oriundo de um experimento social realizado com crianças no bairro da Liberdade, por meio de oficina de fotografia, visita de campo guiada pelas crianças, jogos de imaginação de cenários futuros, expressão por meio do desenho e desenvolvimento de maquetes. Com o olhar voltado para o brincar, o experimento objetivou fomentar a participação ativa das crianças no planejamento de espaços e equipamentos de caráter lúdico, além de trabalhar os conceitos de participação cidadã, protagonismo infantil, democracia, sustentabilidade, direito à cidade e direto de brincar na cidade. O ensaio retratou a situação do bairro e a percepção das crianças sobre seu lugar de brincadeira, durante o experimento.
Yabani Zeytinde Vermikompost, Deniz Yosunu Özü ve Gibberellik Asit Uygulamalarının Çimlenme ve Çöğür Gelişimine Etkisi
Authors: GÜNERİ Murat 
Published: July 2023

Özet:
Bu çalışmada deniz yosunu özü ve gibberellik asit (GA3) priming uygulamaları ile vermikompost uygulamasının yabani zeytin tohumlarında bitki çıkış oranı ve çöğür gelişimine etkisinin belirlenmesi amaçlanmıştır. Tohumlar 12 Şubat 2021 tarihinde ekilmiş, ilk bitki çıkışları 15 Aralık 2021 tarihinde başlamıştır. Bitki çıkış oranı, % 34.67 (20 g l-1 deniz yosunu özü) – % 62.67 (% 20 vermikompost) arasında tespit edilmiştir. Çöğür gelişim parametrelerinde uygulamalar arasındaki fark önemli olup, sürgün sayısı dışındaki diğer parametrelerde en düşük değerler kontrol bitkilerinde en yüksek ise % 40 vermikompost uygulamasında tespit edilmiştir. Zeytin fidanı üretim sürecinde, başta vermikompost olmak üzere, deniz yosunu özü ve GA3 kullanımının yararlı olabileceği sonucuna varılmıştır.
ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT ĐIỀU TRỊ GÃY KÍN 1/3 GIỮA XƯƠNG ĐÒN BẰNG NẸP VÍT KHÓA TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ VINH
Authors: Trường Nguyễn Hồng , Hiếu Nguyễn Trọng , Chỉnh Dương Đình , Long Nguyễn Thanh 
Published: July 2023

Mục tiêu: Đánh giá kết quả phẫu thuật điều trị gãy kín 1/3 giữa xương đòn bằng nẹp vít khóa tại Bệnh viện Đa khoa thành phố Vinh.
Đối tượng và phương pháp: Nghiên cứu mô tả ở 54 bệnh nhân gãy kín 1/3 giữa xương đòn được phẫu thuật tại Bệnh viện Đa khoa Thành phố Vinh từ tháng 1/2021 đến tháng 4/2023.
Kết quả: 92,6% bệnh nhân xương thẳng trục hết di lệch chiếm 92,6%, không có trường hợp nào xương còn di lệch nhiều sau nắn chỉnh; Liền vết mổ kỳ đầu chiếm 98,1%, 1,9% bị nhiễm trùng vết mổ; 48/49 bệnh nhân can xương chiếm 98%, can xương tốt có tỉ lệ là 85,7%, can xương xấu là 12,3%, có 2% không liền xương; không có biến chứng trong mổ, 87,7% có kết quả tốt về phục hồi chức năng vận động khớp vai theo thang điểm Constant – Murley; 85,8% có kết quả chung tốt.
Kết luận: Bệnh nhân gãy xương đòn được phẫu thuật nẹp vít khóa có tỉ lệ hết di lệch rất cao, liền vết mổ tốt, can xương tốt ở phần lớn các bệnh nhân, chức năng vận động khớp và kết quả chung chiếm tỉ lệ cao, ít biến chứng.
ĐÁNH GIÁ CHẤT LƯỢNG CUỘC SỐNG SAU CAN THIỆP “TUỔI GIÀ KHOẺ MẠNH” TẠI CHÍ LINH, HẢI DƯƠNG VÀ KIM BÔI, HOÀ BÌNH NĂM 2018-2021
Authors: Anh Nguyễn Đình , Đức Dương Minh , Hà Bùi Thị Thu 
Published: July 2023

Đặt vấn đề: Việt Nam tiến tới điểm ngoặt với quy mô dân số già vào năm 2015. Nhưng người cao tuổi (NCT) tại Việt Nam chưa thực sự khoẻ mạnh.
Mục tiêu: Bài báo này nhằm đánh giá sự thay đổi chất lượng cuộc sống của NCT trước và sau khi can thiệp (giai đoạn 2018-2021) của mô hình “Già hoá khoẻ mạnh” đã được triển khai tại 4 xã của thành phố Chí Linh, Hải Dương và huyện Kim Bôi, Hoà Bình.
Phương pháp: Nghiên cứu sử dụng thiết kế bán thử nghiệm với so sánh trước và sau can thiệp nhằm đánh giá hiệu quả của can thiệp. Tổng số NCT tham gia là 1260 người với 2 khoảng thời gian thu thập số liệu là tháng 1-4/2018 và tháng 1-4/2022.
Kết quả: Kết quả cho thấy điểm chất lượng cuộc sống (CLCS) dao động trong khoảng 5,96 cho tới 8,09 với điểm CLCS chung ở nhóm can thiệp (7,20) cao hơn có ý nghĩa thống kê so với nhóm chứng (6,96). Kết luận: Mô hình can thiệp “Tuổi già khoẻ mạnh” là một mô hình hiệu quả giúp tăng cường CLCS của người cao tuổi.
KẾT QUẢ ĐIỀU TRỊ KHÁNG SINH KẾT HỢP DẪN LƯU ÁP XE GAN TẠI BỆNH VIỆN NGUYỄN TRI PHƯƠNG
Authors: Long Huỳnh Thanh , Khiêm Nguyễn Mạnh , Khương Phạm Việt 
Published: July 2023

Đặt vấn đề: Dẫn lưu áp xe gan qua da là phương pháp điều trị ban đầu được lựa chọn cho những ổ áp xe có kích thước lớn hơn 5 cm đã hóa lỏng âm từ lâu đã được áp dụng tại nhiều bệnh viện tại Việt Nam.
Mục tiêu: Đánh giá hiệu quả điều trị áp xe gan bằng kháng sinh kết hợp dẫn lưu dưới hướng dẫn siêu âm.
Phương pháp nghiên cứu: Nghiên cứu hồi cứu các bệnh nhân (BN) áp xe gan đã được điều trị kháng sinh vừa kết hợp dẫn lưu ổ áp xe dưới hướng dẫn siêu âm tại Bệnh viện Nguyễn Tri Phương từ tháng 01/2017 đến tháng 12/2022.
Kết quả: Có 61 BN được đưa vào nghiên cứu. Tỷ lệ nam/nữ là 1,65/1; trung bình 56,1 ± 12,3 tuổi, tiền sử đái tháo đường chiếm 32,8%; triệu chứng lâm sàng nổi bật là sốt (88,5%), đau hạ sườn phải (85,2%). Ổ áp xe gan nằm ở gan phải chiếm 73,4%, đa phần là đơn ổ (78,7%). Kháng sinh điều trị đầu tay là Cephalosporin thế hệ III kết hợp Metronidazol truyền tĩnh mạch, đa số nhạy với Cephalosporin thế hệ III (49,2%), 8,2% là vi khuẩn đa kháng tiết ESBL sử dụng Carbapenems. Tỷ lệ điều trị thành công cao (96,7%).
Kết luận: Điều trị áp xe gan bằng kháng sinh kết hợp dẫn lưu dưới hướng dẫn siêu âm là một biện pháp hiệu quả và an toàn. Hầu hết các trường hợp đều chỉ can thiệp thủ thuật 1 lần với tỷ lệ thành công cao.
Career development planning in women's handball elite players – middle ranking countries specifics
Authors: Bon Marta , Wilson Gahan Susan , Pori Primož , Doupona Mojca 
Published: July 2023

The purpose of this qualitative research was to study the outcomes of career development of women’s handball players through longitudinal systematic observation. The purpose was to identify the sociocultural factors and personal characteristics that enabled athletes from geographically small countries with middle-ranking national handball teams to fulfil their quality of life aspirations and trajectories in combination with professional sporting career goals.
Data collection commenced in 2012 when all athletes participated in semi structured interviews. A total of fourteen interviews were conducted – eight with Slovenian women’s national team athletes and six with Swiss national team athletes. All athletes were ranked in the top ten players in their national teams, all had played more than 50 international matches.

Systematic observation of the athletes also commenced in 2022 and continued for seven years with records made of the career development of each player and their migration patterns, and their respective career transitions. At the conclusion of the observation phase, the eight migrant players who were still actively playing handball were re-interviewed.
The study concluded that access to dual career prospects, represent key points of successful career development in women’s handball players from geographically small countries with middle-ranking national handball teams. The model of a successful female athletes from geographically small countries with middle-ranking national handball team identified several key factors for success. These factors included excellent handball skills; a successful dual career pattern; an adequate level of education and, a migration experience, and realisation of their quality of life aspirations and trajectories as significant factors in evaluating their success, both as athletes and on a personal level external to sport.