bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rift Valley fever and malaria co‐infection: A case report
Authors: Ali Yousif , Siddig Emmanuel Edwar , Mohamed Nouh , Ahmed Ayman 
Published: September 2023

Key Clinical MessageWe report a case of febrile illness that was presented with mild symptoms. However, laboratory investigation confirmed a malaria and Rift Valley fever co‐infection. Healthcare providers in settings endemic with several infectious diseases should seek rolling out possibilities of other infections prior to starting treatment for achieving effective case management with less resources and better safety of patients.AbstractHere we report a case of febrile illness that confirmed to be a co‐infection of malaria and Rift Valley fever. The patient was initially diagnosed with malaria and started on treatment immediately. However, due to the lack of response to the treatment further laboratory investigations were pursued.
Controlling the Formation of Electroactive Graphene‐Based Cementitious Composites: Towards Structural Health Monitoring of Civil Structures
Authors: Safuta Małgorzata , Ciesielski Artur , Samorì Paolo 
Published: September 2023

AbstractThe development of composites combining multiple components each one imparting a specific function to the ensemble is highly sought after for disruptive applications in chemistry and materials science, with a particular importance for the realization of smart structures. Here, we report on the development of an unprecedented multifunctional cementitious composite incorporating reduced graphene oxide (rGO). By design, this material features significantly enhanced electrical properties while retaining the excellent cement's hydration and microstructure. The multiscale investigation on the chemical and physical properties of the dispersion made it possible to establish an efficient preparation protocol for rGO aqueous dispersion as well as rGO‐based cementitious composites using a commercial poly(carboxylate ether)‐based superplasticizer. The conduction mechanisms within the matrix of rGO containing mortars were unraveled by electrochemical impedance spectroscopy revealing conductive paths originating from bulk cement matrix and rGO nanosheets in composites with rGO loadings as low as 0.075 wt. %. For this rGO loading, we observed the reduction of the resistivity of bulk cement mortar layers from 18.3 MΩ cm to 2.8 MΩ cm. Moreover, the addition of 0.2 wt. % of rGO resulted in the formation of rGO conductive paths with the resistivity of 51.1 kΩ cm. These findings represent a major step forward towards the practical application of graphene‐based materials in structural health monitoring of concrete structures.
Interrelations between Linkage Isomers of an Efficient Square‐planar Nickel(II) Nitrite Photoswitch in the Solid State
Authors: Potempa Kinga , Deresz Krystyna A. , Jankowska Joanna , Jarzembska Katarzyna N. , Krówczyński Adam , Mikhailov Artem , Schaniel Dominik , Kamiński Radosław 
Published: September 2023

AbstractAn efficient nitrite nickel(II) photoswitch, with the 1‐phenyl‐2‐hydroxyimino‐3‐[(2’‐dimethylamino)ethyl]imino‐1‐propanone moiety used as the ancillary ligand, is reported. In the ground‐state (‘dark’) crystal structure, the studied compound exists predominantly as the nitro‐(η1‐N(O)2) isomer, however, traces of the exo‐ and endo‐nitrito‐(η1‐ONO) forms are detected both at 100 K (4–5 % each) and under ambient conditions (~9 % each). When excited with the 405–530 nm LED light, the nitro‐to‐nitrito isomerization takes place. The total conversion exceeds 90 %. The exo‐nitrito linkage isomer constitutes the dominant photo‐generated form, whereas the relative population of both nitrito species depends on temperature. The reaction is fully reversible and reproducible. The photo‐products are stable up to 200 K. The system constitutes a good model case for the reaction mechanism studies. Thus, experimental and theoretical investigations on the photo‐isomerism were conducted and are presented in detail. Eventually, the nitro→exo‐nitrito→endo‐nitrito reaction pathway is proposed.
Visible‐Light‐Promoted Palladium‐Catalyzed Cross‐Couplingof Iodocarboranes with Disulfides and Phenylselenyl Chloride†
Authors: Li Shimeng , Liu Yizhen , Xie Zuowei 
Published: September 2023

Comprehensive SummaryThis work describes a general method for the synthesis of a series of sulfenylated and selenylated carboranes at room temperature using readily available iodocarboranes as starting materials via boron‐centered carboranyl radicals. Such hypervalent boron radicals are generated by a visible‐light‐promoted Pd(0)/Pd(I) pathway. They are useful intermediates and can be trapped by disulfides and phenylselenyl chloride for the convenient construction of B—S/Se bonds.
Application of Mendelian randomization in the discovery of risk factors for coronary heart disease from 2009 to 2023: A bibliometric review
Authors: Zhong Dayuan , Cheng Hui 
Published: September 2023

AbstractCoronary heart disease (CHD) is a life‐threatening condition that poses a significant risk to individuals. Mendelian randomization (MR) is an emerging epidemiological research method that offers substantial advantages in identifying risk factors for diseases. Currently, there are ongoing CHD‐related MR studies. To gain comprehensive insights into the focal areas and trends of CHD‐related MR research, this study utilizes bibliometrics to conduct an in‐depth analysis of CHD‐related MR articles published in the core database of Web of Science (WOS) from 2009 to 2023. A search was performed to identify CHD‐related MR articles published between 2009 and 2023 in WOS. The data, including publication countries, research institutions, journals, citations, and keywords, were analyzed using the Bibliometrix R‐4.0 software package. A total of 111 articles published in 71 journals were included in the analysis. The journal with the highest impact factor (IF) was the New England Journal of Medicine. The articles were distributed across 24 categories within the 71 journals, with the highest number of publications falling under Cardiac & Cardiovascular Systems, Medicine, General & Internal, and Genetics & Heredity. Among the articles, 57 were published in Q1 journals, 42 in Q2 journals, 9 in Q3 journals, and 2 in Q4 journals. The most frequently published journals on CHD‐related MR were Frontiers in Cardiovascular Medicine, Frontiers in Genetics, and the Journal of the American College of Cardiology. A total of 963 authors participated in the 111 articles, with the majority affiliated with institutions in the United Kingdom, the US, and China. The national cooperation network revealed close collaborations between the UK and the US, as well as between the UK and China. The publication of the 111 articles involved 453 research institutions, with Oxford University, Bristol University, and Cambridge University being the most frequently involved institutions. Out of the 111 articles, only 62 were directly related to CHD and MR, with CHD being the outcome factor in 61 of them. These 61 articles investigated 47 exposure factors across eight categories. Among these factors, 10 had been studied in more than 2 articles. The findings concerning the impact of serum uric acid and omega‐6 fatty acids on CHD risk were not entirely consistent. Research in MR related to CHD has been gradually gaining recognition, with an increase in both its academic credibility and collaborative efforts within this field. Indeed, MR has facilitated the identification of risk factors associated with CHD. However, the relationship between these disease risk factors and CHD requires further investigation for clarification. Future MR studies on CHD could prioritize the elucidation and validation of contentious disease risk factors, thereby paving the way for a more comprehensive exploration of additional factors contributing to the onset of CHD.
Volitional inspiration is mediated by two independent output channels in the primary motor cortex
Authors: Helou Leah B. , Dum Richard P. 
Published: September 2023

AbstractThe diaphragm is a multifunctional muscle that mediates both autonomic and volitional inspiration. It is critically involved in vocalization, postural stability, and expulsive core–trunk functions, such as coughing, hiccups, and vomiting. In macaque monkeys, we used retrograde transneuronal transport of rabies virus injected into the left hemidiaphragm to identify cortical neurons that have multisynaptic connections with phrenic motoneurons. Our research demonstrates that representation of the diaphragm in the primary motor cortex (M1) is split into two spatially separate and independent sites. No cortico–cortical connections are known to exist between these two sites. One site is located dorsal to the arm representation within the central sulcus and the second site is lateral to the arm. The dual representation of the diaphragm warrants a revision to the somatotopic map of M1. The dorsal diaphragm representation overlaps with trunk and axial musculature. It is ideally situated to coordinate with these muscles during volitional inspiration and in producing intra‐abdominal pressure gradients. The lateral site overlaps the origin of M1 projections to a laryngeal muscle, the cricothyroid. This observation suggests that the coordinated control of laryngeal muscles and the diaphragm during vocalization may be achieved, in part, by co‐localization of their representations in M1. The neural organization of the two diaphragm sites underlies a new perspective for interpreting functional imaging studies of respiration and/or vocalization. Furthermore, our results provide novel evidence supporting the concept that overlapping output channels within M1 are a prerequisite for the formation of muscle synergies underlying fine motor control.
Preparation of Palladium‐Doped Nickel Phosphide Nanoparticles as Efficient Electrocatalysts for Alkaline Hydrogen Evolution Reaction
Authors: Kim Ju Ho , Kim Suhyeon , Lestarini Dian Tri , Pramadewandaru Respati K. , Hong Jong Wook , Bang Jiwon 
Published: September 2023

AbstractHydrogen production through electrochemical water splitting has gained significant attention owing to its environmental benefits over traditional methods. However, designing an efficient electrocatalyst for the hydrogen evolution reaction (HER) in an alkaline electrolyte remains a significant challenge. In this study, colloidal Pd‐doped Ni2P nanoparticles were prepared via a thermal decomposition‐based strategy and used as electrocatalysts for the hydrogen evolution reaction. The Pd dopant is atomically dispersed within the Ni2P nanoparticles, regulating their electronic structure and providing an efficient active site for hydrogen production. The Pd‐doped Ni2P nanoparticles exhibited excellent electrocatalytic performance with an overpotential of 77 mV at 10 mA cm−2 in an alkaline electrolyte and a small Tafel slope of 46 mV dec−1.
Surface Passivation of Perovskite Solar Cells with Oxalic Acid: Increased Efficiency and Device Stability
Authors: Cheng Nian , Li Weiwei , Zheng Dingshan , Yang Wen‐Xing 
Published: September 2023

AbstractSolution processed perovskite films usually exhibit numerous defect states on the surfaces of the films. Here in this work, oxalic acid (H2C2O4), which has two C=O groups, is selected and used to passivate the surface defects of the two‐step deposited perovskite films via post‐treatment. Strong interaction between H2C2O4 molecule and the Pb2+ ions located on the surface of perovskite film has been confirmed via Fourier transform infrared spectroscopy and X‐ray photoelectron spectroscopy, which can result in an effective suppress of the surface defects. Furthermore, time‐resolved PL spectrum indicates that carrier lifetime is prolonged in the H2C2O4 passivated perovskite film. After optimizing the H2C2O4 concentration, the target perovskite solar cells can demonstrate superior power conversion efficiencies (21.67 % from reverse measurement and 21.54 % from forward measurement) and superior device‐stability.
Regulating the Content of Donor Unit in Donor–Acceptor Covalent Triazine Frameworks for Promoting Photocatalytic H2Production
Authors: He Wei , Zhou Jing , Xu Wenhua , Li Chengbo , Li Jun , Wang Ning 
Published: September 2023

AbstractUsing their own triazine groups as natural receptors, the introduction of various donor units to construct donor‐receptor configuration in covalent triazine frameworks (CTFs) has been shown to be an effective strategy to improve photocatalytic activity. In this work, the effect of donor unit content (D‐content) on the photoelectric properties and photocatalytic activity of CTFs was thoroughly investigated. Four analogous CTFs with different D‐content have been rationally designed and synthesized, in which the bithiophene (Btp) as the donor unit and triazine as the acceptor unit. And CTF‐Btp with the highest D‐content showed the best photocatalytic activity. The experimental and theoretical results indicated this improvement is attributed to stronger visible light absorption capacity and higher photoinduced charge carrier separation efficiency. This study elucidates the relationship between the structural features of CTFs with varying D‐content and their photocatalytic activity, offering a promising strategy for developing efficient photocatalysts.
A novel compact semicircular defected ground structure ultrawideband monopole antenna integrated with Ku band for breast cancer detection
Authors: Subrahmanyam Grandhi Venkata , Krishna Kalva Sri Rama 
Published: September 2023

SummaryA compact and novel ultrawideband (UWB) antenna integrated with Ku band for microwave imaging applications is reported. The reported antenna consists of a novel patch structure along with a tapered feed structure on top of FR‐4 substrate having a compact dimension of 16 × 22 mm2 and novel semicircular defected ground structure (SC‐DGS) etched below the substrate. The proposed antenna covers a wide impedance bandwidth of 15.07 GHz spanning from 3.51 to 18.58 GHz with a fractional bandwidth (FBW) of 136%. The intended antenna performance is analyzed for S11, peak gain, efficiency, and radiation patterns in frequency domain, and group delay, isolation (S21), and linear phase response in time domain. The simulated and measured results of reported antenna are well matched for the usage in practical portable UWB applications. More importantly, the proposed antenna system is simulated for the detection of breast cancer tissue by comparison of S21 results, current densities, and specific absorption rate with and without tumor conditions. These findings show that the radiator and the whole system work well in detecting the breast tumor.
A case of asymptomatic gastric plexiform fibromyxoma followed up for 3 years
Authors: Sugimura Naomi , Kubota Eiji , Sasaki Makiko , Fukusada Shigeki , Mizuno Yusuke , Iwasaki Hiroyasu , Tanaka Mamoru , Ozeki Keiji , Shimura Takaya , Kataoka Hiromi 
Published: September 2023

AbstractPlexiform fibromyxoma is a rare mesenchymal tumor identified in recent years and presents as a gastrointestinal submucosal tumor that is typically located in the gastric antrum. We report a case of gastric plexiform fibromyxoma in which the diagnosis was difficult despite repeated tissue sampling. Before visiting our hospital, the patient had been followed up for 3 years without a definitive diagnosis despite serial examinations, including computed tomography, endoscopy, endoscopic ultrasound, and endoscopic ultrasound‐guided fine‐needle aspiration. Endoscopic ultrasound‐guided fine‐needle aspiration was reperformed, and endoscopic submucosal dissection for deep biopsy was conducted for differential diagnosis of the tumor. However, histological analysis with immunostaining of tumor samples obtained using these techniques cannot provide a reliable diagnosis. Finally, the tumor was resected surgically because of its increasing size, and subsequent microscopic analysis revealed a multinodular plexiform growth pattern of spindle‐like cells with myxoid stroma. Immunohistochemically, the tumor cells were positive for smooth muscle actin but negative for c‐kit, CD34, and S100. Based on these findings, the patient was diagnosed with plexiform fibromyxoma. No evidence of residual or recurrent tumors was observed at 24 months postoperatively.
The practicality of practice: A model of the function of play behaviour
Authors: Mallpress Dave E. W. , Špinka Marek 
Published: September 2023

AbstractThe function of play has been a long‐debated topic in animal behaviour. One popular class of accounts is that play offers practice for serious adult behaviour, but little has been done to model the circumstances where this could be true. In this paper, we model an individual who, over the juvenile and subadult ontogenetic periods, has a choice between three behaviours: foraging, playing and rest, where playing improves an individual's ability in some component of a serious adult behaviour. Using stochastic dynamic programming, we show that even when play is more energetically costly and an inferior form of practice than foraging itself, it still may be optimal to play under a variety of circumstances. We offer several instantiations of the play as practice concept to show the possibility of play improving a variety of different adult abilities: antipredatory, foraging and reproductive behaviour. These models show the environmental conditions where play might be expected, as well as the predicted occurrences of play throughout ontogeny. This is a first step in showing the ecological feasibility of the practice hypothesis of play and raises further questions about why playful activity is more beneficial than more deliberate directed practice.
Maternal dexamethasone exposure does not affect glucose tolerance but alters renal haemodynamics in F1 rats in a sex‐dependent manner
Authors: Malatiali Slava A. , Kilarkaje Narayana , Al‐Bader Maie 
Published: September 2023

AbstractIntroductionPrenatal programming with dexamethasone increases the risk of the development of hyperglycaemia and insulin resistance, leading to diabetes in adulthood. Dexamethasone also causes a decline in renal glomerular filtration in the adult offspring. Sodium‐glucose cotransporter‐2 (SGLT2) plays a significant role in regulating blood glucose and renal haemodynamics in diabetic patients. However, the role of SGLT2 in dexamethasone‐induced programming and the putative sex‐dependent effects on the changes named earlier is unknown. Therefore, this study aimed to investigate the impact of maternal dexamethasone treatment on glucose tolerance, insulin sensitivity, renal perfusion and renal function in adult male and female offspring and the possible contribution of SGLT2 to these changes.Methods and ResultsPregnant Sprague Dawley rats (F0) were treated with either vehicle or dexamethasone (0.2 mg/kg ip) from gestation Day 15 to 20. F1 males and F1 females were randomly selected from each mother at 4 months of age. There was no change in serum Na+, Na+ excretion rate, glucose tolerance or insulin sensitivity in F1 male or female rats. However, dexamethasone caused significant glomerular hypertrophy and decreases in CSinistrin and CPAH indicating decreased glomerular filtration rate and renal plasma flow, respectively, in dexamethasone‐treated F1 male but not female rats. Dexamethasone did not affect SGLT2 mRNA or protein expression in F1 males or females.ConclusionWe conclude that dexamethasone‐mediated prenatal programming of glomerular volume, renal function and haemodynamics is sex‐dependent, occurring only in adult male offspring.
Association of hypoxic burden metrics with cardiovascular outcomes in heart failure and sleep‐disordered breathing
Authors: Huang Boping , Huang Yan , Zhai Mei , Zhou Qiong , Ji Shiming , Liu Huihui , Zhuang Xiaofeng , Zhang Yuhui , Zhang Jian 
Published: September 2023

AbstractAimsHeart failure (HF) and sleep‐disordered breathing (SDB) frequently coexist. We aimed to compare the prognostic value of different nocturnal hypoxic burden metrics in hospitalized HF patients.Methods and resultsHF patients underwent polygraphy screening for SDB in this prospective cohort. Hypoxic burden metrics assessed using pulse oximetry included time < 90% oxygen saturation (T90), proportion of total recording time < 90% oxygen saturation (TRT90), oxygen desaturation index (ODI), and mean oxygen saturation (meanSO2). The prespecified endpoints were the composite of cardiovascular death or admission for worsening HF. This study included 764 hospitalized HF patients, 16.5% and 36.6% of whom had obstructive and central sleep apnoea, respectively. With a median follow‐up time of 2.2 years, endpoint events occurred in 410 (53.7%) patients. In univariate and multivariate analyses, T90, TRT90, and meanSO2 were substantially associated with the composite outcome, whereas ODI was not. After multivariate Cox model adjustment, patients with 5.0 ≤ T90 ≤ 52.0 min [hazard ratio (HR) 1.32, 95% confidence interval (CI): 1.02–1.71, P = 0.034] or T90 > 52.0 min (HR 1.56, 95% CI: 1.21–2.02, P = 0.001) had a greater risk of the composite outcome than those with T90 < 5.0 min. The TRT90 and T90 results were similar. Compared with meanSO2 > 95%, meanSO2 < 93% (HR 1.47, 95% CI: 1.16–1.88, P = 0.002) was correlated with adverse outcomes.ConclusionsThe hypoxic burden metrics T90, TRT90, and meanSO2, but not ODI, were independent predictors of cardiovascular death or readmission for worsening HF. Indicators of duration and severity, not just the frequency of nocturnal hypoxaemia, should be valued and considered for intervention to improve outcomes in HF patients.
Beneficial Effect of Acetic Acid on the Formation of FeIII(OOH) Species and on the Catalytic Activity of Bioinspired Nonheme FeII Complexes.
Authors: Bercy Roxanne , Rebilly Jean‐Noël , Herrero Christian , Guillot Régis , Maisonneuve Hélène , Banse Frédéric 
Published: September 2023

AbstractThree new amine/pyridine FeII complexes bearing pentadentate ligand with one, two or three electron enriched 4‐methoxy‐3,5‐dimethylpyridine were used as catalysts for the oxidation of small organic molecules by hydrogen peroxide. The distribution of products formed suggests that these ligands are not enough electron donating to promote the O−O heterolytic cleavage of the oxidant in order to generate selective FeV(O) species. Using acetic acid in the reaction mixtures results in a significant increase of the efficiency of these catalytic systems. Our investigations show that the use of AcOH leads to the protonation/dissociation of a pyridyl moiety and the formation of (N4)FeII(OAc)(OH) species. These complexes readily react with excess hydrogen peroxide to yield (N4)FeIII(OAc)(OOH) intermediates. These latter intermediates are proposed to evolve into (N4)FeIV(OAc)(O), which are more efficient than the usual (N4)FeIV(O) and (N5)FeIV(O).