bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accumulation Levels of Available Cu and Cu Absorption in Corn in Ultisolss and Alfisolss After the Addition of Fly Ash and Organic Materials
Authors: Purwanto Benito Heru , Hanudin Eko , Destri Erin 
Published: April 2023

Fly ash was a byproduct of burning coal in thermal power plants that can be used in agriculture as a source of micronutrients. This study aimed to determine the effect of fly ash combined with Biochar and Manure on the chemical properties of the soil, plant growth, and the absorption of Cu corn plants. The study design used a randomized design of factorial groups, with soil type factors namely Alfisols and Ultisols with three repeats. Agronomic observations include plant height, dry weight of roots and headers. Laboratory analysis includes preliminary soil, Fly Ash, Manure, Biochar, soil analysis after harvest, and Cu in leaf. The results showed that the availability of Cu elements in Ultisols was higher by 5.37 mg/kg than Alfisols with an average of 3.90 mg/kg. Cu absorption in maize crops grown in Alfisols soil was greater with an average of 54.7 mg/g when compared to those planted in Ultisols soil by an average of 50.3 mg/g. The treatment between Fly Ash and Manure in a ratio of 1:1 has a tendency to increase Cu absorption with a value of 68 mg/g. Alfisols soil was significantly correlated with organic matter to Cu absorption in Corn plants with a value of R= 0.827. The conclusion of this study was that the availability of Cu elements in Ultisols soil was higher than in Alfisols soil and Cu uptake in corn plants was lower after being treated with the addition of manure and Biochar and corn plant growth was better.
Experience of Using the INTRABEAM System to Determine the Safely Tolerated Dose During Intraoperative Irradiation of Malignant Gliomas
Authors: Gorozhanin A. V. , Soshin Yu. V. , Dreval O. N. , Belyaikin E. V. 
Published: April 2023

Glioblastoma is the most malignant primary brain tumor. For treatment uses a combined regimen that is currently available: surgery, radiation and chemotherapy. However, so far the median survival of patients does not exceed 14 months. In this connection, there is a constant search for effective methods. Improvement in radiation therapy has led to the possibility of its intraoperative, which is a practical and effective method aimed at getting rid of the remaining tumor cells, reducing the spread of the tumor and filling the therapeutic gap between surgery and subsequent chemotherapy and radiation therapy. Intraoperative radiation therapy (IORT) allows you to deliver the required tumoricidal dose exactly to the target, minimally affecting the surrounding healthy tissues.Goal: Establishment of the safety of intraoperative irradiation of patients with malignant gliomas with the INTRABEAM device (Carl ZEISS, Germany) with a dose of up to 40 Gy on the applicator.Material and methods: The study involved 15 patients, the average age of which was 51 years, the ratio of men and women was 4:6, the average Karnofsky index before surgery was 97. After surgical removal of the tumor, an express biopsy was performed. Next, intraoperative irradiation was performed with the INTRABEAM device (Carl ZEISS) at a dose of 40 Gy, followed by an assessment of the Karnofsky index, early postoperative and delayed possible complications.Results: In all patients operated on with intraoperative irradiation and subsequent adjuvant radiochemotherapy, the method was well tolerated, there were no wound healing features or identified complications, there were no cases of wound liquorrhea, wound inflammation.Conclusion: Intraoperative irradiation after surgical removal of the tumor can be recommended as a safe method for the treatment of malignant gliomas in addition to existing combination therapy.
Characteristics of Blood Levels of Vascular Endothelial Growth Factor A (VEGFA) and Its Receptors in Men with Malignant Brain Gliomas with Different Responses to Combination Therapy
Authors: Kaplieva I. V. , Sheiko E. A. , Vlasov S. G. , Sakun P. G. , Frantsiyants E. M. , Engibaryan M. A. , Pogorelova Y. A. , Trepitaki L. K. 
Published: April 2023

Relevance: Glial tumors (GTs) amount for about 60 % of all primary CNS tumors. GTs highly express VEGF. Standard approaches to GT treatment do not involve modification of the radiation therapy plan. Adaptive stereotactic radiotherapy (ASRT) allows such correction. The combination of ASRT with bevacizumab (B) or dexamethasone (D) improves the outcomes of patients with GTs, but the effectiveness of therapy varies from patient to patient. B and D are known to have different effects on malignant glioma cells and components of the VEGF system.Purpose: To reveal specific levels of the VEGF system components in the blood of men with cerebral GTs with different effectiveness of combination ASRT.Material and methods. One month after radical surgery, men with GTs received ASRT with standard fractionation on the Novalis Tx linear accelerator (Varian): single fraction dose = 2 Gy, total dose = 60 Gy, 30 fractions, using a three-layer stereotaxic mask. ASRT was combined with B (i/v, 5 mg/kg, once every 2 weeks), n = 30, and with D (i/m, 4 mg, twice a day during 45 days), n = 30. Blood levels of VEGFA, sVEGFR1 and sVEGFR2 were measured by IFA before and after ASRT.Results: Before treatment (ASRT+D), levels of VEGFA were 1.5 times (р < 0.01) higher, and sVEGFR1 was 3.1 times lower in patients with future progression, compared with patients with other responses to treatment; in partial response, sVEGFR was 1.8 times (р < 0.01) higher than in stabilization. After treatment (ASRT+D), sVEGFR1 levels reduced by 1.4 times (р < 0.001) in stabilization and by 2.2 times in partial response, together with VEGFA increase by 3.0 times in stabilization only; in progression, sVEGFR1 increased by 2.3 times. Before treatment (ASRT+B), levels of VEGFA in patients with partial and complete responses were on average 1.4 times (р < 0.01) lower than in stabilization; sVEGFR1 in partial response was 4.4 times lower than in stabilization and 2.2 times lower than in complete response; sVEGFR2 in complete response was 1.3 times (р < 0.02) lower than in partial response. After treatment (ASRT+B), VEGFA levels elevated: in complete and partial responses on average by 14.8 times, in stabilization by 9.7 times.Conclusions: In men with cerebral GTs, blood levels of the VEGF system components before treatment differed in patients with different future responses to combination ASRT with B or D, which allows prediction of the effectiveness of such therapy even before it is started. This connection is especially obvious for combination ASRT with B.
PSMA‑Targeted Radioligand Therapy with the Radiopharmaceutical <sup>177</sup>Lu‑PSMA‑617 in a Patient with Metastatic Castration‑Resistant Prostate Cancer
Authors: Geliashvili T. M. , Krylov A. S. , Bliganov P. I. , Dolgushin B. I. , Pronin A. I. , Tyulyandina A. S. , Parnas A. V. , Ryzhkov A. D. , Pavlova A. V. 
Published: April 2023

The expression of prostate-specific membrane antigen (PSMA) on the surface of prostate cancer cells is increased with tumor progression, which is the basis for a theranostic approach in the treatment of these patients. The PSMA ligand, labeled with the therapeutic radionuclide lutetium-177 (177Lu), delivers 177Lu beta particle radiation to PSMA-expressing prostate cancer cells. Currently, PSMA-targeted radioligand therapy with the radiopharmaceutical 177Lu-PSMA-617 is approved for the therapy of patients with metastatic castration-resistant prostate cancer (mCRPC). We present a clinical case of successful use of this method of treatment in our center in a patient with mCRPC, progressing after two lines of therapy — hormone therapy with new generation of androgen signal inhibitors (abiraterone, enzalutamide) and chemotherapy with docetaxel.
Central Diabetes Insipidus in Langerhans Cell Histiocytosis: A Case Report
Authors: Lestari Dya Mulya , Eka Agustia Rini  
Published: April 2023

Background: Diabetes insipidus (DI) is part of a group of hereditary or acquired polyuria and polydipsia diseases. Diabetes insipidus can be caused by central and nephrogenic disorders. This study aimed to describe the etiologies, clinical symptoms, and management of central diabetes insipidus in Langerhans cell histiocytosis.
Case presentation: A 4 years 4 months old boy came with excessive and frequent micturition since 9 months ago. The patient drinks 4-5 L per day and still feels thirsty. The patient had a history of Langerhans cell histiocytosis (LCH). During laboratory work-up, urine osmolarity decreased, and serum osmolarity and electrolyte were normal. The patient was diagnosed with central diabetes insipidus with Langerhans cell histiocytosis. The treatment given to the patient is desmopressin.
Conclusion: Langerhans cell histiocytosis may affect any organs of the body. The long-term management of diabetes insipidus in Langerhans cell histiocytosis requires measurement to prevent dehydration and, at the same time to prevent water intoxication. The focus of management is based on the education of the patient about the importance of regulating their fluid intake according to the patient’s hydration status.
Mapeo de la percepción individual y del entorno organizacional para la práctica clínica basada en la evidencia entre enfermeras renales en España
Authors: Cobo-Sánchez José Luis , Cirera-Segura Francisco , García-Martínez Mirian , Vieira-Barbosa Lopes Luis Miguel , Jaume-Riutort Catalina , Hernando-García Julia , Marrero-Fernández Pilar , Moreno García Miguel Ángel , González-García Fernando , Larrañeta-Inda Irene , Ulzurrún-García Ana , Casas-Cuesta Rafael , Ila-García Andrés , Blanco-Mavillard Ian 
Published: April 2023

Objetivo: Analizar la percepción de las enfermeras renales en España en relación con el entorno organizacional para la práctica clínica basada en la evidencia (PCBE); y determinar qué factores profesionales y del contexto influenyen esta percepción.
Material y Método: Estudio observacional transversal multiéntrico, en 15 servicios de nefrología de distitos hospitales en España y 2 centros de diálisis. Se utilizaron los instrumentos Practice Environment Scale of Nursing Work Index (PES-NWI) y Evidence Based Practice Questionnarie (EBPQ). Se realizó un análisis estadístio descriptivo, bivariado (ANOVA, Kruskall-Wallis), y regresión logística con la puntuación total del EBPQ como variable dependiente.
Resultados: Se recibieron 397 encuestas (participación84,28%), tras depuración encuestas, fueron válidas 382 (81,1% población): 82,7% mujeres, edad media 42 años, media de experiencia profesional como enfermera 18,2 años (12,2 años en nefrología), 94,8% clínicas, 81,9% de hemodiálisis. Puntuación media PES-NWI 62,35±15,10 (IC:95% 60,78-48,06). Presentaron menores puntuaciones en algunos factores del PES-NWI las enfermeras de centros >500 enfermeras, que trabajan en hemodiálisis y >11 años de experiencia profesional. Las enfermeras gestoras presentaron mayores puntuaciones en todos los factores del PES-NWI. Puntuación media EBPQ 81,05±21,92 (IC:95% 78,70-83,4). Presentaron mayores puntuaciones en varios factores del EBPQ las enfermeras con menor experiencia profesional, mejor puntuación en PES-NWI y que poseían estudios de postgrado.
Conclusiones: Los factores que más influyen en la percepción de las enfermeras renales en España son la experiencia profesional, el rol dentro de la organización, un contexto favorable y la formación de postgrado.
Pendampingan Branding Produk Sebagai Strategi Graduasi Keluarga Penerima Manfaat Program Keluarga Harapan Di Kelurahan Kepanjen Kidul
Authors: Nafasari Zarin , Mawarni Sutrisna Lala , Susilowati Tiyas , Purwito Lasi 
Published: April 2023

Mahasiswa Kajian dan Praktik Lapangan Universitas Negeri Malang bersama Dinas Sosial Kota Blitar melaksanakan pengabdian kepada masyarakat terkait dengan pendampingan branding produk kue kecipir yang diproduksi oleh Keluarga Penerima Manfaat Program Keluarga Harapanelurahan Kepanjen Kidul Kota Blitar. Motif dibalik pelaksanaan program ini yaitu kurangnya kemampuan sasaran dalam hal branding/marketing sehingga produk kue kecipir belum dikenal oleh masyarakat luas. Tujuan program pendampingan ini adalah membantu mengembangkan usaha kelompok KPM PKH Kelurahan Kepanjen Kidul sebagai salah satu strategi graduasi mandiri. Metode pelaksanaan kegiatan yaitu dengan observasi dan pendampingan praktik. Hasil dari kegiatan ini adalah KPM PKH mampu; 1) merencanakan desain label/stiker sebagai ciri khas produk; 2) membuat slogan; 3) menuliskan identitas KPM PKH Kelurahan Kepanjen Kidul agar diketahui oleh calon konsumen, dan dapat menentukan pilihan desain warna serta kemasan agar semakin menarik sehingga mempermudah promosi dan meningkatkan daya jual produk. Diharapkan program pengembangan pendampingan branding produk kue kecipir dapat terus dilakukan secara merata di wilayah Kota Blitar agar masyarakat sasaran menjadi lebih mandiri secara finansial sehingga mampu membantu pemerintah dalam membangun ekonomi produktif.
Contemporaneous Observations of Hα Luminosities and Photometric Amplitudes for M Dwarfs
Authors: García Soto Aylin , Newton Elisabeth R. , Douglas Stephanie T. , Burrows Abigail , Kesseli Aurora Y. 
Published: April 2023

Abstract
While many M dwarfs are known to have strong magnetic fields and high levels of magnetic activity, we are still unsure about the properties of their starspots and the origin of their magnetic dynamos. Both starspots and chromospheric heating are generated by the surface magnetic field; they produce photometric variability and Hα emission, respectively. Connecting brightness variations to magnetic activity therefore provides a means to examine M-dwarf magnetism. We survey 30 M dwarfs previously identified as fast rotating stars (P
rot < 10 days). We present time-series optical photometry from the Transiting Exoplanet Survey Satellite (TESS) and contemporaneous optical spectra obtained using the Ohio State Multi-Object Spectrograph (OSMOS) on the 2.4 m Hiltner telescope at MDM Observatory in Arizona. We measure rotation periods and photometric amplitudes from TESS light curves using Gaussian Processes. From the OSMOS spectra, we calculate the equivalent width of Hα, and L
Hα
/L
bol. We find a weak positive correlation between Hα luminosity and the semiamplitude, R
var (

p
=

0.005

−
0.005

+
0.075

). We also observe short-term variability (between 20 and 45 minutes) in Hα equivalent widths and possible enhancement from flares consistent to recent literature.
Wave Conversion, Decay, and Heating in a Partially Ionized Two-fluid Magneto-atmosphere
Authors: Cally Paul S. , Gómez-Míguez M. M. 
Published: April 2023

Abstract
A ray-theoretic phase-space description of linear waves in a two-fluid (charges and neutrals) magnetized plasma is used to calculate analytic decay rates and mode transmission and conversion coefficients between fast and slow waves in two dimensions due to finite ion–neutral collision frequencies at an arbitrary ionization fraction. This is relevant to partially ionized astrophysical plasmas, in particular solar and stellar atmospheres. The most important parameter governing collisional effects is the ratio of the wave frequency to the neutral–charges collision frequency, ϵ = ω/ν
nc, with secondary dependence on ionization fraction and wave attack angle. Comparison is made to the one-fluid magnetohydrodynamic case, and it is found that acoustic-to-acoustic and magnetic-to-magnetic transmission through the Alfvén-acoustic equipartition layer is decreased by a term of


(

ϵ

2

)

relative to one-fluid (infinite collision frequency), and correspondingly acoustic-to-magnetic and magnetic-to-acoustic conversion is increased. The neutral-acoustic mode is shown to dissipate rapidly as ν
nc → ∞. Away from the mode conversion region, dissipative decay along the remaining magneto-acoustic rays scales as


(
ϵ
)

and is found to be much more effective on magnetically dominated rays compared to acoustically dominated rays. This produces a steep jump in dissipation in mode conversion regions, where the rays change character, and can produce localized heating there and beyond. Applications to the solar chromosphere are discussed.
Classification of Blazar Candidates of Unknown Type in Fermi 4LAC by Unanimous Voting from Multiple Machine-learning Algorithms
Authors: Agarwal A. 
Published: April 2023

Abstract
The Fermi fourth catalog of active galactic nuclei (AGNs) data release 3 (4LAC-DR3) contains 3407 AGNs, out of which 755 are flat spectrum radio quasars (FSRQs), 1379 are BL Lacertae objects (BL Lac objects), 1208 are blazars of unknown (BCUs) type, while 65 are non-AGNs. Accurate categorization of many unassociated blazars still remains a challenge due to the lack of sufficient optical spectral information. The aim of this work is to use high-precision, optimized machine-learning (ML) algorithms to classify BCUs into BL Lac objects and FSRQs. To address this, we selected the 4LAC-DR3 Clean sample (i.e., sources with no analysis flags) containing 1115 BCUs. We employ five different supervised ML algorithms, namely, random forest, logistic regression, XGBoost, CatBoost, and neural network with seven features: photon index, synchrotron-peak frequency, pivot energy, photon index at pivot energy, fractional variability, ν
F
ν, at synchrotron-peak frequency, and variability index. Combining results from all models leads to better accuracy and more robust predictions. These five methods together classified 610 BCUs as BL Lac objects and 333 BCUs as FSRQs with a classification metric area under the curve >0.96. Our results are significantly compatible with recent studies as well. The output from this study provides a larger blazar sample with many new targets that could be used for forthcoming multiwavelength surveys. This work can be further extended by adding features in X-rays, UV, visible, and radio wavelengths.
Spicules in IRIS Mg ii Observations: Automated Identification
Authors: Herde Vicki L. , Chamberlin Phillip C. , Schmit Don , Bose Souvik , Daw Adrian , Milligan Ryan O. , Polito Vanessa 
Published: April 2023

Abstract
We have developed an algorithm to identify solar spicules in the first ever systematic survey of on-disk spicules exclusively using Mg ii spectral observations. Using this algorithm we identify 2021 events in three Interface Region Imaging Spectrograph (IRIS) data sets with unique solar feature targets spanning a total of 300 minutes: (1) active region, (2) decayed active region/active network, and (3) coronal hole. We present event statistics and relate occurrence rates to the underlying photospheric magnetic field strength. This method identifies spicule event densities and occurrence rates similar to previous studies performed using Hα and Ca ii observations of active regions. Additionally, this study identifies spicule-like events at very low rates at magnetic field intensities below 20 G, and increasing significantly between 100 and 200 G in active regions and above 20 G in coronal holes, which can be used to inform future observation campaigns. This information can be be used to help characterize spicules over their full lifetimes, and compliments existing Hα spectral capabilities and upcoming Lyα spectral observations with the Solar eruptioN Integral Field Spectrograph (SNIFS) sounding rocket. In total, this study presents a method for detecting solar spicules exclusively using Mg ii spectra, and provides statistics for spicule occurrences in the Mg ii h line with respect to the magnetic field strength for the purpose of predicting spicule occurrences.
Pest characteristics of Trigonorhinus sp. (Coleoptera: Anthribidae) and the developmental process of its galls in Caragana liouana Zhao Y. Chang and Yakovlev
Authors: Zhang Yanru , Hu Yaru , Jiang Haiyan , Zhao Shengguo , Lei Jingwen , Wang Ruigang , Chen Yuhong 
Published: April 2023

Abstract
In recent years, a Trigonorhinus sp. (Coleoptera) has caused serious damage to Caragana liouana Zhao Y. Chang and Yakovlev, a major ecological restoration shrub in China. Here, we survey the occurrence and damage pattern of Trigonorhinus sp. and its galls and compare the growth of affected and unaffected plants. Trigonorhinus sp. larvae usually infest the main trunk and lateral branches of the plant, causing the affected branches to become partially swollen and verrucose. Galls develop in stages depending on whether eggs are laid in May or July and proceed in sequence over three years from egg-laying to formation, expansion, dormancy, maturity, dormancy, maturity, and death. Galls inhibit plant development to some extent. On average, six (at least one, and no more than 18; standard error of the mean = 3) larvae occupy each gall, and the number of larvae within a gall did not significantly affect gall size. Gall size significantly affected branch dieback, and large-diameter infested branches had larger galls. This study clarifies the growth dynamics of Trigonorhinus sp. galls and provides a basis for further research into the growth mechanism of the species’ galls.
Perceptions and acceptance of COVID-19 vaccine among pregnant and lactating women in Singapore: a pre-vaccine rollout cross-sectional study
Authors: Jayagobi Pooja Agarwal , Ong Chengsi , Yeo Kee Thai , Lim Caleb Chun Wei , Seet Meei Jiun , Kwek Lee Koon , Ku Chee Wai , Chan Jerry Kok Yen , Mathur Manisha , Chua Mei Chien 
Published: April 2023

Abstract

Introduction:
Vaccination is critical in controlling the coronavirus disease 2019 (COVID-19) pandemic. However, vaccine perception and acceptance among pregnant and lactating women is unknown in Singapore. We aimed to determine the acceptance of COVID-19 vaccination among these two groups of women in Singapore and the factors associated with vaccine acceptance.

Methods:
We conducted an anonymous, online survey on the perceptions of the COVID-19 vaccine and its acceptance by pregnant and lactating women at a tertiary maternal and child hospital in Singapore from 1 March to 31 May 2021. Information on their demographics and knowledge was collected. These factors were assessed for their relationship with vaccine acceptance.

Results:
A total of 201 pregnant and 207 lactating women participated. Vaccine acceptance rates in pregnant and lactating women were 30.3% and 16.9%, respectively. Pregnant women who were unsure or unwilling to take the vaccine cited concerns about safety of the vaccine during pregnancy (92.9%), while lactating women were concerned about its potential long-term negative effects on the breastfeeding child (75.6%). Factors that were positively associated with vaccine acceptance included a lower monthly household income or education level, appropriate knowledge regarding vaccine mechanism and higher perceived maternal risk of COVID-19. Most pregnant (70.0%) and lactating women (83.7%) were willing to take the vaccine only when more safety data during pregnancy and breastfeeding were available.

Conclusion:
COVID-19 vaccine acceptance was low among pregnant and lactating women in Singapore. Addressing the safety concerns when more data are available and education on the mechanism of vaccine action will likely improve acceptance among these women.