bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversity of Red Yeasts in Various Regions and Environments of Poland and Biotechnological Potential of the Isolated Strains
Authors: Kot Anna M. , Sęk Wioletta , Kieliszek Marek , Błażejak Stanisław , Pobiega Katarzyna , Brzezińska Rita 
Published: August 2023

AbstractDue to the growing demand for natural carotenoids, researchers have been searching for strains that are capable of efficient synthesis of these compounds. This study tested 114 red yeast strains collected from various natural environments and food specimens in Poland. The strains were isolated by their ability to produce red or yellow pigments in rich nutrient media. According to potential industrial significance of the carotenoids, both their total production and share of individual carotenoids (β-carotene, γ-carotene, torulene, and torularhodin) were analyzed. The total content of carotenoid pigments in the yeast dry matter ranged from 13.88 to 406.50 µg/g, and the percentages of individual carotenoids highly varied among the strains. Most of the yeast isolates synthesized torulene at the highest amount. Among the studied strains, isolates with a total carotenoid content in biomass greater than 200 µg/g and those containing more than 60% torularhodin were selected for identification (48 strains). The identified strains belonged to six genera: Rhodotorula, Sporidiobolus, Sporobolomyces, Buckleyzyma, Cystofilobasidium, and Erythrobasidium. The largest number of isolates belonged to Rhodotorula babjevae (18), Rhodotorula mucilaginosa (7), Sporidiobolus pararoseus (4), and Rhodotorula glutinis (4).
Effects and plasma proteomic analysis of GLP-1RA versus CPA/EE, in combination with metformin, on overweight PCOS women: a randomized controlled trial
Authors: Liao Mingyu , Li Xing , Zhang Hao , Zhou Ling , Shi Liu , Li Weixin , Shen Rufei , Peng Guiliang , Zhao Huan , Shao Jiaqing , Wang Xiujie , Sun Zheng , Zheng Hongting , Long Min 
Published: August 2023

Abstract
Purpose
Polycystic ovary syndrome (PCOS) is characterized by reproductive dysfunctions and metabolic disorders. This study aims to compare the therapeutic effectiveness of glucagon-like peptide-1 receptor agonist (GLP-1RA) + Metformin (Met) versus cyproterone acetate/ethinylestradiol (CPA/EE) + Met in overweight PCOS women and identify potential proteomic biomarkers of disease risk in women with PCOS.

Methods
In this prospective, open-label randomized controlled trial, we recruited 60 overweight PCOS women into two groups at a 1:1 ratio to receive CPA/EE (2 mg/day: 2 mg cyproterone acetate and 35-μg ethinylestradiol,) +Met (1500 mg/day) or GLP-1 RA (liraglutide, 1.2–1.8 mg/day) +Met (1500 mg/day) for 12 weeks. The clinical effectiveness and adverse effects were evaluated, followed by plasma proteomic analysis and verification of critical biomarkers by ELISA.

Results
Eighty(80%) patients completed the study. Both interventions improved menstrual cycle, polycystic ovaries, LH(luteinizing hormone) and HbA1c(hemoglobin A1c) levels after the 12-week treatment. GLP-1RA + Met was more effective than CPA/EE + Met in reducing body weight, BMI (Body Mass Index), and waist circumference, FBG(fasting blood glucose), AUCI(area under curve of insulin),TC (Total Cholesterol), IL-6(Interleukin-6) and improving insulin sensitivity, and ovulation in overweight women with PCOS, with acceptable short-term side effects. CPA/EE + Met was more effective in improving hyperandrogenemia, including T(total testosterone), LH, LH/FSH(Luteinizing hormone/follicle-stimulating hormone), SHBG(sex hormone-binding globulin) and FAI (free androgen index). By contract, GLP-1RA+Met group only improved LH. Plasma proteomic analysis revealed that the interventions altered proteins involved in reactive oxygen species detoxification (PRDX6, GSTO1, GSTP1, GSTM2), platelet degranulation (FN1), and the immune response (SERPINB9).

Conclusions
Both CPA/EE+Met and GLP-1RA + Met treatment improved reproductive functions in overweight PCOS women. GLP-1RA + Met was more effective than CPA/EE + Met in reducing body weight, BMI, and waist, and improving metabolism, and ovulation in overweight women with PCOS, with acceptable short-term side effects. CPA/EE + Met was more effective in reducing hyperandrogenemia. The novel plasma biomarkers PRDX6, FN1, and SERPINB9, might be indicators and targets for PCOS treatment.

Trial registration ClinicalTials.gov Trial No:
NCT03151005. Registered 12 May, 2017, https://clinicaltrials.gov/ct2/show/NCT03151005.
Armut im Jugendamt
Authors: Hunold Martin 
Published: August 2023

ZusammenfassungDer Allgemeine Soziale Dienst (ASD) im Jugendamt kann die Armut der Welt nicht beseitigen, aber sie konsequent als gesellschaftliche Gewalt analysieren. Im Folgenden wird danach gefragt, wie in und durch Organisation die Armut von jungen Menschen und ihren Familien macht- und gewaltanalytisch reflektiert und den Adressat_innen ermächtigende Hilfen zur Armutsbewältigung angeboten werden können.
Social and dimensional comparison effects in general and domain-specific test anxiety: a nested factor modeling approach
Authors: Talić Irma , Sparfeldt Jörn R. , Möller Jens , Renner Karl-Heinz , Greiff Samuel , Niepel Christoph 
Published: August 2023

AbstractThe generalized internal/external frame of reference (GI/E) model assumes social and dimensional achievement comparisons to form self-perceptions. These domain-specific comparisons have been shown to shape two facets of test anxiety (i.e., worry and emotionality) both directly and indirectly through academic self-concepts. However, examinations of such domain-specific relations have rarely integrated general components, although the hierarchical nature of both test anxiety and academic self-concept is well-known. Thus, the present study implemented a nested factor modeling approach. We examined social and dimensional comparison effects on worry and emotionality as well as mediation effects of academic self-concepts in the math and verbal domains while controlling for general components. We contrasted this approach with the conventionally used first-order factor model where general components were not considered. Data from N = 348 German secondary school students (Mage = 15.3 years, Grades 9–10) were analyzed using structural equation models. Direct negative within-domain and positive cross-domain achievement-anxiety relations emerged, yet, the pattern of cross-domain relations changed across modeling approaches. Only the nested factor model showed indirect cross-domain mediation relations. Our findings suggest the importance of structural representations of hierarchical constructs. The nested factor model approach enhanced predictions within the GI/E model, particularly those related to dimensional comparisons.
Validation of the short grit scale (Grit-S) in Chinese physical education teachers
Authors: Du Yongqing , Yao Cheng-Kui , Chang Siqi , Zeng Xiaojin , Luo Jie 
Published: August 2023

AbstractThe Short Grit Scale (Grit-S) is a popular instrument used to assess trait-level perseverance and passion for long-term goals in students and/or professional populations. This study examined the psychometric properties and construct validity of the Grit-S in a survey sample of Chinese physical education teachers (N = 256, 26.6% females, Mage = 33.96 years, SDage = 6.04 years). Confirmatory factor analysis indicated that the Grit-S scores supported the proposed two-factor model, comprising consistency of interest and perseverance of effort as subscales. Moreover, as expected, the Grit-S subscale scores showed acceptable internal consistency as well as satisfactory convergent and criterion validity, correlating with scores of external criteria variables (e.g., Big Five personality traits, self-control, and work burnout). These findings suggest that the Grit-S is an effective instrument for assessing grit in Chinese physical education teachers.
Non-operative Management and Outcomes of Femoroacetabular Impingement Syndrome
Authors: Pasculli Rosa M. , Callahan Elizabeth A. , Wu James , Edralin Niam , Berrigan William A. 
Published: August 2023

Abstract
Purpose
To serve as a guide for non-operative physicians in the management of femoroacetabular impingement syndrome and provide an algorithm as to when to refer patients for potential surgical management.

Recent Findings
Supervised physical therapy programs that focus on active strengthening and core strengthening are more effective than unsupervised, passive, and non-core-focused programs. There is promising evidence for the use of intra-articular hyaluronic acid and PRP as adjunct treatment options. Recent systematic reviews and meta-analyses have found that in young active patients, hip arthroscopy demonstrates improved short-term outcomes over physical therapy.

Summary
The decision for the management of FAIS is complex and should be specific to each patient. Consideration of the patient’s age, timing to return to sport, longevity of treatment, hip morphology, and degree of cartilage degeneration is required to make an informed decision in the treatment of these patients.
Try to See it My Way: Humans Take the Level-1 Visual Perspective of Humanoid Robot Avatars
Authors: Wahn Basil , Berio Leda , Weiss Matthias , Newen Albert 
Published: August 2023

AbstractVisual perspective taking (VPT) is a fundamental process of social cognition. To date, however, only a handful of studies have investigated whether humans also take the perspective of humanoid robots. Recent findings on this topic are conflicting as one study found no evidence for level 1 VPT (i.e., which object is seen by the agent) and a different study has found evidence for level 2 VPT (i.e., how is the object seen by the agent). The latter study proposed that the human-like appearance of robots triggers VPT and that a mental capacity to perceive the environment is not required (mere-appearance hypothesis). In the present study, we tested whether the mere-appearance hypothesis is also applicable to level 1 VPT. We manipulated the appearance of a humanoid robot by either showing it with a human-like or artificial head, and its mental capacity for perception by presenting it as switched on or off. We found that all manipulations triggered VPT, showing, in contrast to earlier findings, level 1 VPT for robots. Our findings support the mere-appearance hypothesis as VPT was triggered regardless of whether the robot was switched on or off, and also show that the mere-appearance hypothesis is robust with regard to alterations of human-like appearance.
An experimental study of wet-cooking in organic vessels: implications for understanding the evolution of cooking technologies
Authors: Langley Andy , Needham Andy , Kröger Roland , Cifuentes-Alcobendas Gabriel , Adegeest Mette , Cousen Jess , Lance Christopher , Benton Hannah , Mansbridge Amy-Rose , Satchell Amanda , Tomlinson Lewis , Rockall-Birtles Francesca , Lucquin Alexandre , Little Aimée 
Published: August 2023

AbstractThe ability to control and direct fire is a major evolutionary step in the human story. The development of aceramic cooking technologies is less well understood as they rarely survive in the archaeological record. However, inferential evidence such as fire-cracked rocks, earthen pits and heated bones suggest a variety of cooking methods were used prior to the invention of ceramics. Yet there is a paucity of experimental evidence testing the efficacy of perishable organic containers in tasks involving their use with heat. The study presents experimental results of organic containers and their use for heating water related to cooking. Containers were made from deer hide and pig stomach and water was heated using two different techniques: placing the container directly above a fire and placing hot stones into the container. The results suggest that different organic containers and heating types could attain and maintain a sub-boiling cooking temperature; however, not all could reach boiling point. It is argued that these sub-boiling methods may be as, or perhaps more, desirable than boiling, with potential implications for the development of vessels prior to the adoption of ceramics.
Feature dimensionality reduction via homological properties of observability
Authors: Trovati Marcello , Farsimadan Eslam 
Published: August 2023

AbstractFeature selection and its subsequent dimensionality reduction are significant problems in machine learning and it is at the core of several data science techniques. The ‘shape’ of data, or in other words its related topological properties, can provide crucial insights into the corresponding data types and sources and it enables the identification of general properties that facilitate its analysis and assessment. In this article, we discuss an information theoretic approach combined with data homological properties to assess dimensionality reduction, which can be applied to semantic feature selection.
Occupational health professionals’ experiences with telehealth services: usage, perceived usefulness and ease of use
Authors: Nissinen Sari , Pesonen Sanna , Toivio Pauliina , Sormunen Erja 
Published: August 2023

Abstract
Background
In occupational health care, telehealth services implementation requires the professionals to change their way of working because they have had to incorporate the telehealth services into their daily routines. Understanding how occupational health professionals relate to and experience telehealth services may aid in its implementation. However, an overview of telehealth services’ use in occupational health care is lacking. The aim of this study was to provide insight into the telehealth services that are used in occupational health care and identify their factors related to occupational health professionals’ perceived usefulness and perceived ease of use.

Methods
The present cross-sectional descriptive study was conducted in May-June 2022 in Finland. An analysis of variance (ANOVA) was run to test the relationships between demographic variables and the rate of usefulness, and ease of use variables. Scheffe test was used to make comparisons among group means in an analysis of variance (ANOVA) experiment.

Results
According to the results that investigated the ease of use of telehealth services, the respondents mostly felt that using telehealth services was easy and easy to learn. Profession, work experience, and information and communication technology skills were determinants related to perceived usefulness of telehealth services, while profession and information and communication technology skills were related to perceived ease of use, respectively.

Conclusions
In this survey, quite a fair agreement was found among occupational health professionals regarding the perceived usefulness and ease of use of telehealth services. However, the study results suggest that occupational telehealth services are most likely to be useful and easy to use when professionals’ information and communication technology skills are at a good level.
Can Sustainable Development Induce Foreign Direct Investment? Analysis of the Complex Inward and Outward Flows of Investment in European Union Countries
Authors: Caetano Rafaela Vital , Marques António Cardoso , Afonso Tiago Lopes 
Published: August 2023

AbstractThe transfer of polluting industries from developed to developing countries and the often-detrimental effects this has on meeting sustainable development goals is well documented, but an analysis of the underlying reasons for this transfer has not been widely examined in the literature. This study seeks to analyse the complexity of Foreign Direct Investment in developed countries and its environmental impacts, by measuring inward and outward investment. A Panel Quantile Regression was undertaken for 14 European Union countries between 1995 and 2018. The results show that, whether countries are recipients or sources of high levels of FDI, the drivers of inward and outward investment are the same, and that sustainable development and renewable energy are both drivers of FDI. The paper also finds that outward Foreign Direct Investment is not driven by environmental regulation, and the regulatory quality of the European Union countries improves its foreign investment balance.
Application of soft computing and evolutionary algorithms to estimate hydropower potential in multi-purpose reservoirs
Authors: Kayhomayoon Zahra , Arya Azar Naser , Ghordoyee Milan Sami , Berndtsson Ronny , Najafi Marghmaleki Sajad 
Published: August 2023

AbstractHydropower is a clean and efficient technology for producing renewable energy. Assessment and forecasting of hydropower production are important for strategic decision-making. This study aimed to use machine learning models, including adaptive neuro-fuzzy inference system (ANFIS), gene expression programming, random forest (RF), and least square support vector regression (LSSVR), for predicting hydroelectric energy production. A total of eight input scenarios was defined with a combination of various observed variables, including evaporation, precipitation, inflow, and outflow to the reservoir, to predict the hydroelectric energy produced during the experimental period. The Mahabad reservoir near Lake Urmia in the northwest of Iran was selected as a study object. The results showed that a combination of hydroelectric energy produced in the previous month, evaporation, and outflow from the dam resulted in the highest prediction performance using the RF model. A scenario that included all input variables except the precipitation outperformed other scenarios using the LSSVR model. Among the models, LSSVR exerted the highest prediction performance for which RMSE, MAPE, and NSE were 442.7 (MWH), 328.3 (MWH), and 0.85, respectively. The results showed that Harris hawks optimization (HHO) (RMSE = 0.2 WMH, MAPE = 10 WMH, NSE = 0.90) was better than particle swarm optimization (PSO) (RMSE = 0.2 WMH, MAPE = 10 WMH, NSE = 0.90) in optimizing ANFIS during the prediction. The results of Taylor’s diagram indicated that the ANFIS-HHO model had the highest accuracy. The findings of this study showed that machine learning models can be used as an essential tool for decision-making in sustainable hydropower production.
Quantitative evaluation of water-alternative-natural gas flooding in enhancing oil recovery of fractured tight cores by NMR
Authors: Liu Baishuo , Yao Chuanjin , Liu Yaqian , Zhao Jia , Lei Zhengdong , Zhou Yiran , Song Yuyuan , Li Lei 
Published: August 2023

AbstractAs the associated gas of tight reservoirs, natural gas is abundant and noncorrosive, which is more suitable for the development of tight oil reservoirs in China. However, the mechanism of gas injection development is unclear, and the gas channeling is serious in tight reservoirs after fracturing. The water-alternating-gas (WAG) flooding is an effective means to delay gas channeling and improve oil recovery. Therefore, it is significant to clarify the mechanism of preventing gas channeling and recovering oil by water-alternation-natural gas (WANG) flooding. The WANG flooding experiments with different water–gas slugs were conducted in non-fracture and fractured tight cores. Besides, the oil distribution of different pore spaces of cores before and after displacement and the main contribution spaces on oil recovery were quantitatively analyzed by using nuclear magnetic resonance and core mercury porosimetry techniques. The results indicate that compared with natural gas flooding, the WANG flooding can retard gas channeling, increase formation energy, and enhance oil recovery by up to 14.1%, especially in fractured cores. Under the resistance of water slugs, the gas was allowed to enter smaller pores and its swept volume was expanded. Oil is mainly stored in mesopores (0.1–1 μm) and small pores (0.01–0.1 μm), accounting for over 90% of the total volume. The oil recovered mainly comes from mesopores, which accounts for over 75% of the total amount. Moreover, the WANG flooding strengthens the recovery of oil in mesopores and macropores (1–10 μm), but it also squeezes oil into small pores and micropores (0.001–0.01 μm).
Amalgamated algebra along an ideal defined by S-noetherian spectrum-like-conditions
Authors: Issoual Mohammed 
Published: August 2023

AbstractLet $$f:A\longrightarrow B$$

f
:
A
⟶
B

be a ring homomorphism and J be an ideal of B. The subring $$A\bowtie ^{f}J:=\{(a,f(a)+j)/ a\in A\quad \text {et}\quad j\in J\}$$

A

⋈
f

J
:
=

{

(
a
,
f

(
a
)

+
j
)

/
a
∈
A

et

j
∈
J
}

of $$A\times B$$

A
×
B

is called the amalgamation of A with B along with J with respect to f. In this paper we investigate a general concept of ring with Noetherian spectrum, called S-Noetherian spectrum property which was introduced by Hamed, on the $$A\bowtie ^{f}J$$

A

⋈
f

J

for a multiplicative subset S of $$A\bowtie ^{f}J.$$

A

⋈
f

J
.
Hardware acceleration design of the SHA-3 for high throughput and low area on FPGA
Authors: Sideris Argyrios , Sanida Theodora , Dasygenis Minas 
Published: August 2023

AbstractIn sensitive communications, the cryptographic hash function plays a crucial role, including in the military, healthcare, and banking, ensuring secure transmission by verifying data integrity and carrying out other vital tasks. Compared to other cryptographic hash algorithms, such as SHA-1 and SHA-2, the Keccak hash function (SHA-3) boasts superior hardware performance and is more resilient to modern cryptanalysis techniques. Nonetheless, hardware performance enhancements, such as boosting speed or reducing area usage, are constantly required. This research focuses on increasing the Keccak hash algorithm’s throughput rate by introducing a novel architecture that reduces the total number of clock cycles required to obtain the result of a hash function. Additionally, the new simplified structure of the round constant (RC) generator design assures a reasonably low area and achieves the highest throughput and efficiency. Thus, when implemented, it achieved the highest throughput of 19.515 Gbps, 24.428 Gbps, 33.393 Gbps, and 36.358 Gbps on FPGA devices with the Virtex-5, Artix-7, Virtex-6, and Virtex-7, respectively. Finally, our approach is compared to recently published designs.
Translation research on testicular germ cell tumors
Authors: Eleveld Thomas F. , Looijenga Leendert H. J. 
Published: August 2023

AbstractTesticular germ cell tumors are the most common malignancy in men aged 14 to 44 years. Although exceptional cisplatin sensitivity results in cure rates of > 90%, resistance can occur for which there are currently no alternative treatment options. Translational research in recent years has led to various breakthroughs in detection and classification of these tumors. The identification of miRNA-371 expression as a marker of malignant testicular germ cell tumors (with the exception of teratomas) enables significantly more sensitive and specific detection of these cancers in various clinical contexts (primary tumor, residual disease, relapse etc.). Moreover, the identification of several genetic aberrations that are associated with treatment resistance and poor outcome, such as TP53 mutations or copy number gain on chromosome 3p, underlines the necessity of genetic screening for improved risk classification of testicular cancer patients.