bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative efficacy of apneic oxygenation with face mask versus face mask alone pre-oxygenation to Prevent desaturation during endotracheal intubation of elective Pediatric surgical patients at St. Peter hospital, Addis Ababa Ethiopia:A single center prospective cohort study
Authors: Gesso Ashenafi Seifu , Regasa Tsion Lemma , Goshu Eyayalem Melese , Woldemariam Lemlem Getachew , Fekede Mulualem Sitot 
Published: July 2023

Abstract

Background
Apneic oxygenation using a nasal cannula is used to deliver oxygen continuously during the apneic period of endotracheal intubation to prevent desaturation. Pre-oxygenation using face mask alone technique may be insufficient to provide a safe apnea period in pediatric patients who are at high risk for rapid desaturation compared to added apneic oxygenation. This study compared the efficacy of apneic oxygenation with a face mask (AO) versus a face mask alone (FMA) pre-oxygenation to prevent desaturation during endotracheal intubation in elective pediatric surgical patients.

Methods
A prospective cohort study was conducted on two equal groups of elective pediatric patients observed in either use of apneic oxygenation with a face mask (AO) or face mask alone(FMA) pre-oxygenation during endotracheal intubation at the study hospital from early December 2021 to late March 2022. The data were collected using a structured questionnaire. The primary outcome variable was the desaturation SpO2 (<94%) observed during endotracheal intubation. The categorical data were analyzed using a χ2-test. Parametric data were analyzed using an independent t-test or one-way ANOVA as appropriate with a 95% CI and a p-value of < 0.05 was considered statistically significant. The Bonferroni post hoc analysis was employed to test the significance of means between the groups.

Results
The mean desaturation level was (SpO2 = 95.74 ± 2.99) in apneic oxygenation with face-mask group and (SpO2 = 93.96 ± 3.74) in the face-mask alone group(p = 0.006) with medium effect size (Cohan’s d = 0.06). A one-way ANOVA showed a statistically significant difference in the mean (±SD) of desaturation level with the number of attempts at endotracheal intubation within the groups (P = 0.005). The Bonferroni pairwise comparison within groups, showed that the mean (±SD) desaturation level during endotracheal intubation for the participant with >2 attempts is significantly lower than for participants with only 1 attempt (p-value = 0.004).

Conclusion and recommendation
A continuous administration of apneic oxygenation (5-l/min) by nasal cannula during endotracheal intubation significantly reduced desaturation in pediatrics. We recommend the use of apneic oxygenation (AO) in pediatrics during intubation time.

Highlights
Reductive Evidentialism and the Normativity of Logic
Authors: Shoaibi Nader 
Published: July 2023

Abstract‘Reductive Evidentialism’ seeks to explain away all ‘structural’ requirements of rationality—including norms of logical coherence—in terms of ‘substantive’ norms of rationality, i.e., responsiveness to evidence. While this view constitutes a novel take on the source of the normativity of logic, I argue that it faces serious difficulties. My argument, in a nutshell, is that on the assumption that individuals with the same evidence can have different rational responses (interpersonal permissivism), the view lacks the resources to maintain its central tenet that an individual’s body of evidence cannot make it rationally permissible for the individual to believe logical inconsistencies (intrapersonal nonpermissivism).
South African university students’ experiences of online group cognitive behavioural therapy: Implications for delivering digital mental health interventions to young people
Authors: Hunt Xanthe , Jivan Dionne C. , Naslund John A. , Breet Elsie , Bantjes Jason 
Published: July 2023

Abstract
Mental disorders are common among university students. In the face of a large treatment gap, resource constraints and low uptake of traditional in-person psychotherapy services by students, there has been interest in the role that digital mental health solutions could play in meeting students’ mental health needs. This study is a cross-sectional, qualitative inquiry into university students’ experiences of an online group cognitive behavioural therapy (GCBT) intervention. A total of 125 respondents who had participated in an online GCBT intervention completed a qualitative questionnaire, and 12 participated in in-depth interviews. The findings provide insights into how the context in which the intervention took place, students’ need for and expectations about the intervention; and the online format impacted their engagement and perception of its utility. The findings of this study also suggest that, while online GCBT can capitalise on some of the strengths of both digital and in-person approaches to mental health programming, it also suffers from some of the weaknesses of both digital delivery and those associated with in-person therapies.
Democracy and Bad Government in Latin America
Authors: Langston Joy K. 
Published: July 2023

This essay reviews the following works:Los últimos años de la reforma agraria mexicana, 1971–1991: Una historia política desde el noroeste. By Luis Aboites Aguilar. Mexico City: El Colegio de Mexico Press, 2022. Pp. 333. Paperback. $280.00. ISBN: 9786075643199.Non-Policy Politics: Richer Voters, Poorer Voters, and the Diversification of Electoral Strategies. By Ernesto Calvo and Maria Victoria Murillo. New York: Cambridge University Press, 2019. Pp. vii + 300. Hardcover. $85.00. ISBN: 97811087497008.97.The Volatility Curse: Exogenous Shocks and Representations in Resource-Rich Democracies. By Daniela Campello and Cesar Zucco. New York: Cambridge University Press, 2021. Pp. vii + 240. Paperback. $39.99. ISBN: 9781108795357.Hybrid Regimes within Democracy: Fiscal Federalism and Subnational Rentier States. By Carlos Gervasoni. New York: Cambridge University Press, 2018. Pp. vii + 290. Paperback. $29.99. ISBN: 9781316510735.Life in the Political Machine: Dominant-Party Enclaves and the Citizens They Produce. By Jonathan Hiskey and Mason Mosely. New York: Oxford University Press, 2020. Pp. vii + 282. Hardcover. $82.00. ISBN: 9780197500408.Conservative Party-Building in Latin America: Authoritarian Inheritance and Counterrevolutionary and Struggle. By James Loxton. New York: Oxford University Press, 2021. Pp. xii + 304. Hardcover. $74.00. ISBN: 9780197537527.Votes for Survival: Relational Clientelism in Latin America. By Simeon Nichter. New York: Cambridge University Press, 2018. Pp. ix + 324. Paperback. $32.99. ISBN: 9781108449502.Local Mexico: Democratic Transitions in an Authoritarian Context. By Patricia Olney. Boulder, CO: First Forum, Lynne Rienner Press, 2018. Pp. 351. Hardcover. $89.95. ISBN: 978-1-62637-683-0.
A speleothem record of seasonality and moisture transport around the 8.2 ka event in Central Europe (Vacska Cave, Hungary)
Authors: Demény Attila , Czuppon György , Kern Zoltán , Hatvani István Gábor , Topál Dániel , Karlik Máté , Surányi Gergely , Molnár Mihály , Kiss Gabriella Ilona , Szabó Máté , Shen Chuan-Chou , Hu Hsun-Ming , May Zoltán 
Published: July 2023

AbstractA stalagmite was collected in northern Hungary from the Vacska Cave, where monitoring and ventilation-based site selection had been conducted. The stalagmite covers the 10–8 ka (relative to AD 1950) period, including the so-called 8.2 ka event, and showed preceding signs of climate change that were evaluated by petrographic observations, 14C activities, Sr concentrations, and stable isotope compositions of calcite and inclusion-hosted water. Comparisons of speleothem records show that isotope peaks at ca. 8.5 ka are related to a regional climate anomaly, rather than to a continental-scale event. In accordance with regional proxy records, the 8.2 ka event was associated with a series of temperature and precipitation amount changes, starting with cooling and a reduction in the winter-to-summer precipitation ratio, and then becoming a humid and warm phase at 8.15 ka. X-ray diffraction-based crystallinity parameter (FWHM) values provided evidence for diagenetic alteration of the stable oxygen isotope compositions of inclusion waters. Nevertheless, the stable hydrogen isotope compositions of inclusion waters and the oxygen isotope values of the host calcite revealed elevated d-excess values, and therefore increased Mediterranean moisture contribution during the 8.2 ka event, which indirectly indicate the southward displacement of moisture transport from the Atlantic Ocean.
Localising linguistic citizenship in England
Authors: Rampton Ben , Cooke Melanie , Bryers Dermot , Winstanley Becky , Leung Constant , Tomei Anthony , Holmes Sam 
Published: July 2023

AbstractWhat's the relevance of ‘Linguistic Citizenship' (LC), a concept developed in southern Africa, to language education in England? LC is committed to democratic participation and voice, to linguistic diversity and the value of sociolinguistic understanding (Stroud 2001), and it provides a framework for contesting linguistic conditions in England, where vernacular multilingualism faces monolingual language education policies and an officially ‘hostile environment for migrants'. In fact, LC lines up with four sources of opposition to this: civil society and small-scale community organisations cultivating heritage language multilingualism; experience of system-wide ‘hospitality to diversity' in education in England in the 1970s & 1980s; c.50 years of linguistics research in Britain; and universities themselves. Drawing on LC's pedigree in sociolinguistics, we then turn to the Hub for Education & Language Diversity, a collaboration between King's and non-profit language organisations which approaches LC as a multi-dimensional programme of language development. This includes BA & MA classes; teacher training (with resonant concepts like ‘diasporic local'); and efforts to broaden ideas about university ‘impact’. Overall, Linguistic Citizenship invites us to reassess the lie of the land in language education, and suggests an array of practical but principled initiatives at different points of the language teaching/university interface.
Dynamic modeling and characterization of compliant cable-driven parallel robots containing flexible cables
Authors: Peng Miaojiao , Xiao Longhai , Chen Qinglin , Wei Guowu , Lin Qi , Zhuo Jiayong 
Published: July 2023

AbstractFlexible cables in cable-driven parallel robots (CDPRs) are easy to be excited and vibrate. Cable vibration will react on the end-effector, causing attitude deviation of the end-effector. The main objective of this study is to accurately model axially moving flexible cables and characterize the dynamic behaviors of associated compliant CDPRs. Firstly, a model for transverse vibration of the axially moving length-variable cable is developed. On this basis, an original nonlinear dynamic model of the CDPRs able to capture the vibration of the cables and the dynamics of the end-effector is proposed. Secondly, the frequency–amplitude relationship of the CDPR is obtained. Moreover, the significance of the excitation effect caused by the axially moving length-variable cables is demonstrated, by comparing the results with and without excitation effect at different frequencies. It turns out that, as the oscillation frequency of the end-effector increases, the end-effector and cables exhibit the dynamics process from steady state to unstable large-amplitude vibration and finally to stable small-amplitude vibration. This indicates that the dynamics of the CDPR exhibit non-linear characteristics, due to the influence of flexible cables. Finally, the proposed dynamic model of compliant CDPRs is validated by experiments performed in the laboratory.
Importance de la nature, des opportunités d’activités, de leur accessibilité et de leur publicisation pour favoriser la santé positive, la participation sociale et l’équité en santé d’Estriens âgés
Authors: Maclure Macha , Bouffard Alyssa , Morin Marie-Kristine , Renaud Clémence , Tessier-Buisson Isabelle , Levasseur Mélanie 
Published: July 2023

RésuméCette étude visait à explorer comment les composantes clés de l’environnement des communautés favorisent les résultantes de santé d’Estriens âgés, plus précisément leur santé positive, leur participation sociale et leur équité en santé. Une étude de cas multiples a été réalisée auprès de cinq communautés estriennes (cas) à l’aide de groupes de discussion focalisée (1/communauté) regroupant un total de 49 participants connaissant bien les communautés respectives, soit 47 aînés, 1 conseillère municipale et 1 technicienne en loisir. En rendant accessible et équitable la réalisation d’activités importantes pour les aînés, la nature, une offre d’activités variée, des moyens de communication efficace et les mesures favorisant l’équité avaient une influence positive sur les résultantes de santé. Des facteurs individuels tels qu’un niveau élevé de scolarité et un statut socioéconomique favorable avaient aussi une influence positive. Ces résultats permettent d’outiller les décideurs souhaitant favoriser un vieillissement actif et en santé.
Metastatic breast cancer to oesophagus: a case report and review of the literature
Authors: J Bhuvana , Pandya Akash , Mehta Maitrik , U Suryanarayana 
Published: July 2023

Abstract

Background:
Secondary oesophageal carcinoma from a breast primary is an infrequent phenomenon. Given the rarity of this presentation, there is a general lack of consensus on management guidelines.

Materials and methods:
Herein, we report a case of a 65-year-old female presented with dysphagia, 14 years post-surgery for breast cancer. She was diagnosed with oesophageal metastases and was treated with combination of systemic chemotherapy, hormonal therapy and local radiotherapy. Our patient tolerated the treatment well and achieved a significant symptomatic improvement post-radiotherapy. We also performed a review of literature on oesophageal metastases from breast primary, aiming to improve the diagnostic accuracy and treatment efficacy in this rare presentation.

Conclusions:
We conclude that patients who present with persistent dysphagia post-breast cancer treatment should undergo an endoscopic ultrasound (EUS)-guided fine-needle biopsy (FNB) to rule out oesophageal metastasis. We suggest systemic chemotherapy with hormonal therapy and radiotherapy for local control as a management of choice in this condition. Even though prognosis is difficult to predict in these patients, this combined modality of treatment seems to achieve better overall survival.
Impact of adherence to exercise interventions on effectiveness in a randomized controlled trial in improving sleep in advanced lung cancer patients: A comparison between aerobic exercise and Tai Chi
Authors: Takemura Naomi , Cheung Denise Shuk Ting , Fong Daniel Yee Tak , Lin Chia-Chin 
Published: July 2023

AbstractObjectivesAdherence plays a vital role in the effectiveness of non-pharmacological interventions. The disappearance of interventions’ effects at follow-up was caused by inadequate self-practice beyond intervention period. The purpose of this study is to examine the factors associated with adherence to aerobic exercise and Tai Chi and the impact of adherence on the short- and long-term effectiveness in improving sleep in patients with advanced lung cancer.MethodsThis study analyzed data collected in a clinical trial that evaluated the effects of aerobic exercise and Tai Chi in patients with advanced lung cancer. Two types of exercises were maintained at the same intensity but with different dosage. A total of 99 patients with advanced lung cancer who were recruited between 2018 and 2020 were included. Data were collected using self-report questionnaires.ResultsFifty participants were randomly assigned to aerobic exercise and 49 to Tai Chi intervention. Higher levels of satisfaction and lower levels of depression were significantly associated with higher attendance and compliance in both groups. Low fatigue levels contributed to higher attendance in Tai Chi. Both attendance and compliance were significantly associated with long-term sleep improvement.Significance of resultsHigher levels of satisfaction and lower levels of depression were important characteristics of attendance and compliance with home-based practice in both groups, whereas lower levels of fatigue uniquely contributed to higher attendance in Tai Chi. Better exercise adherence improves long-term effectiveness of sleep in patients with advanced lung cancer. Adopting strategies is imperative to promote exercise adherence in patients with greater levels of depression and fatigue.
Rip Currents Off Rocky‐Shore Surge Channels
Authors: MacMahan Jamie , Thornton Ed , Patria Nick , Gon Casey , Denny Mark 
Published: July 2023

AbstractMore than half the world's coastlines are rocky, but rip‐current dynamics on these topographically complex shores have not been studied. Field experiments on a typical rocky shore using video, drifters, and in‐situ current meters and pressure sensors reveal that incoming narrow‐banded swells result in incident wave groups that force breakpoint low‐frequency (LF) waves, which act in phase inside the surf zone to generate set‐up, run‐up, overtopping, and mass flux, pooling water atop the shore. Set‐up is enhanced by the change in momentum of the LF waves owing to dissipation by bottom friction over the rough seafloor, and by depth‐limited breaking, evidenced by low reflection. A 1D momentum balance results in a mean bottom‐drag coefficient of 1 owing to the rough bottom and vegetation. During wave‐group minima, the hydraulic head of the pooled water forces a return flow through a network of incised feeder channels that converge to a primary surge channel, directing flow offshore. The rip current extends three surf‐zone widths offshore with a maximum velocity of 1 m/s, and (in contrast to sandy shores) flow exits the surf zone, augmenting cross‐shore transport. Rip current strength is a function of channel hypsometry, overtopping, and exit constriction, factors that vary with the tide. As the tide rises, the mean flow decreases as the hydraulic head decreases and the constriction diminishes. Similar to rip currents on sandy beaches, rip currents on rocky shores are modulated by tides and sea‐swell, but they differ in geometric scale and forcing mechanism.
Using Lunar Granulites to Constrain Re‐Equilibration Timescales of Contact Thermal Metamorphism on the Moon
Authors: Pernet‐Fisher J. F. , Joy K. H. , Hartley M. E. 
Published: July 2023

AbstractRocks of the lunar granulite suite are the product of high‐temperature metamorphism within the Moon's crust. However, to date, their formation conditions have few constraints. Here, we combine Ti‐in‐pyroxene element diffusion modeling and two‐pyroxene thermometry with thermal modeling of the lunar crust in order to assess potential heat sources that could generate granulite metamorphism within the lunar highland crust. For the samples investigated in this study, the pyroxene crystals experienced peak metamorphic temperatures between ∼1,027 and 1,091°C over timescales ranging from ∼153 years to ∼15.1 Kyrs. To best satisfy these temperature and timescale constraints, hot (∼2,300°C) impact melt sheets with thickness ranging from 350 m to 3.35 km—equating to impact crater diameters between ∼60 and 280 km—have the potential to heat the underlying anorthositic crust. Deep (>20 km) igneous bodies, such as the large (>10 km thick) sills observed by the GRAIL mission near the base of the lunar crust, also have the potential to generate the required peak metamorphic temperatures; however, the thermal equilibration timescales in this scenario are modeled to be much larger (>100 Kyrs) than was witnessed by the granulites investigated. Our modeling highlights that while lunar granulites are only a minor component within the Apollo and meteorite collection, they are likely an important and ubiquitous lithology within the lunar highland crust.
Investigating Whistler‐Mode Wave Intensity Along Field Lines Using Electron Precipitation Measurements
Authors: Tsai Ethan , Artemyev Anton , Angelopoulos Vassilis , Zhang Xiao‐Jia 
Published: July 2023

AbstractElectron fluxes in Earth's radiation belts are significantly affected by their resonant interaction with whistler‐mode waves. This wave‐particle interaction often occurs via first cyclotron resonance and, when intense and nonlinear, can accelerate subrelativistic electrons to relativistic energies while also scattering them into the atmospheric loss cone. Here, we model Electron Losses and Fields INvestgation’s (ELFIN) low‐altitude satellite measurements of precipitating electron spectra with a wave‐electron interaction model to infer the profiles of whistler‐mode intensity along magnetic latitude assuming realistic waveforms and statistical models of plasma density. We then compare these profiles with a wave power spatial distribution along field lines from an empirical model. We find that this empirical model is consistent with observations of subrelativistic (<200 keV) electron precipitation events, but deviates significantly for relativistic (>200 keV) electron precipitation events at all MLTs, especially on the nightside. This may be due to the sparse coverage of wave measurements at mid‐to‐high latitudes which causes statistically averaged wave power to be likely underestimated in current empirical wave models. As a result, this discrepancy suggests that intense waves likely do propagate to higher latitudes, although further investigation is required to quantify how well this high‐latitude population can account for the observed relativistic electron precipitation.
The JAK1/2 inhibitor ruxolitinib in patients with COVID-19 triggered hyperinflammation: the RuxCoFlam trial
Authors: Hammersen J. , Birndt S. , Döhner K. , Reuken P. , Stallmach A. , Sauerbrey P. , La Rosée F. , Pfirrmann M. , Fabisch C. , Weiss M. , Träger K. , Bremer H. , Russo S. , Illerhaus G. , Drömann D. , Schneider S. , La Rosée P. , Hochhaus A. 
Published: July 2023

AbstractDysregulated hyperinflammatory response is key in the pathogenesis in patients with severe COVID-19 leading to acute respiratory distress syndrome and multiorgan failure. Whilst immunosuppression has been proven to be effective, potential biological targets and optimal timing of treatment are still conflicting. We sought to evaluate efficacy and safety of the Janus Kinase 1/2 inhibitor ruxolitinib, employing the previously developed COVID-19 Inflammation Score (CIS) in a prospective multicenter open label phase II trial (NCT04338958). Primary objective was reversal of hyperinflammation (CIS reduction of ≥25% at day 7 in ≥20% of patients). In 184 patients with a CIS of ≥10 (median 12) ruxolitinib was commenced at an initial dose of 10 mg twice daily and applied over a median of 14 days (range, 2–31). On day 7, median CIS declined to 6 (range, 1–13); 71% of patients (CI 64–77%) achieved a ≥25% CIS reduction accompanied by a reduction of markers of inflammation. Median cumulative dose was 272.5 mg/d. Treatment was well tolerated without any grade 3–5 adverse events related to ruxolitinib. Forty-four patients (23.9%) died, all without reported association to study drug. In conclusion, ruxolitinib proved to be safe and effective in a cohort of COVID-19 patients with defined hyperinflammation.