bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of eco-efficiency in Vietnam during 1990-2017 under Tapio decoupling analysis and Malmquist productivity index approach
Authors: Tạ Thị Hương 
Published: July 2023

The relationship between economic development accompanied by environmental friendliness, and ecological balance is the top concern of the strategic planners of sustainable development in each country. Based on Tapio decoupling analysis and measure productivity index from Malmquist - Data Envelopment Analysis Vietnam’s eco-efficiency during 1990-2017 was investigated. The outstanding results are as follows: Since 2004 onwards, the changes have been recorded in the relationship between affluence and the environment - the ecosystem under the gradual diversity of degrees: expansive decoupling; weak decoupling; expansive coupling, and strong decoupling under Tapio decoupling analysis. At the same time, the Malmquist productivity index has improved slightly with 4.4% over 28 studied years. It shows that Vietnam gradually approaching and implementing strategies for improving the quality of the environment and the ecosystem. However, there is still an upward trend in the amount of emission with an annual emission growth rate of 43.4% while the economic development rate has not shown balance and similarities. Therefore, the reform of management policy, scientific strategy, and updating of technology system should be considered and implemented synchronously to maintain this change and promote the development in a more positive direction.
Effects of performance appraisals on employee productivity in the banking sector in Kenya
Authors: Bula Hannah Orwa , Kamaru Samuel Kimani 
Published: July 2023

Banks have implemented performance appraisals to enhance employee productivity whichwas triggered by the high targets set across the industry. The aim of this study was todetermine the effects of appraisals in line with the impact of performance appraisal criteria,feedback, and reward and competence assessment on employee productivity in these banks.The significance of the study is therefore of great importance to the Banks managementteams and the Banks employees. This research was based on three theories which include theAdam‘s Equity Theory, Goal Setting theory and the implicit theory which underpins thisstudy.
This research applied descriptive research design. The target population was all commercialbanks in Kenya. The sampled banks were selected from a list of banks in Kenya as per theCentral Bank
Classification using the systematic sampling technique. Primary data was collected using aquestionnaire which was coded and entries made into Statistical package for social sciencesfor analysis. Both descriptive and inferential analyses were carried out. The study concludedthat the main performance appraisal indicators used significantly influence employeeproductivity in Kenya‘s banking sector. It is therefore recommended that the salary receivedby the employees be commensurate with their job description and employees should receivepromotion based on their productivity and that they should be taken for further trainingfrequently.
Poster Tiga Bahasa untuk Meningkatkan Motivasi Belajar-Mengajar
Authors: Akbar Taufiq , Andrijanto M. Sjafei 
Published: July 2023

Tujuan kegiatan abdimas adalah membuat poster menggunakan 3 bahasa untuk sarana memotivasi proses belajar-mengajar bagi guru. Metode pelaksanaan melalui beberapa kegiatan, di antaranya survei dan observasi, menentukan konten poster, pembuatan poster, dan penempatan media. Hasil dari kegiatan abdimas adalah 3 poster yang didesain dengan menggunakan 2 software desain yang berbeda fungsi, pertama adalah software Adobe Illustrator dan Adobe Photoshop. Software adobe ilustrator digunakan untuk membuat desain penunjang, yang berbasis vektor, sedangkan adobe photoshop digunakan untuk mengatur tata letak ilustrasi dan tipografi yang diterapkan pada desain poster tersebut. Bahasa yang dipakai dalam poster adalah dilihat dari kepragmatisan sebuah bahasa. Bahasa poster lebih mengutamakan fungsi daripada struktur gramatikalnya. Hal itu sesuai dengan prinsip bahasa dalam poster adalah singkat, padat, jelas, dan mudah diingat. Hasil poster adalah kertas dengan ukuran A3 (30x40cm) dan (40x60cm). Menggunakan ilustrasi yang menggambarkan betapa pentingnya memahami ayat-ayat dalam Al-Quran ditunjukkan dengan memunculkan ilustrasi bulan sabit. Bulan sabit, dalam agama Islam dimaknai penghargaan dengan waktu. Warna hijau daun pisang, dipilih sesuai filosofi warna yang memvisualkan warna kehidupan, keteduhan, yang disesuaikan dengan konsep yang diusung pada poster edukasi tiga bahasa yang membahas tentang anjuran kebaikan dalam bersosialisasi pada keseharian di lingkungan sekolah bagi para santri SDIT Nurul Yaqien
PERCEPTION AND PRACTICES REGARDING COVID-19 VACCINE AMONG MBBS STUDENTS
Authors: Admin Prof. Dr. Sahibzada Masood Us Syed , Syeda Sara Sherazi  , Imran Idrees Butt  , Akram Saeed  , Mahnoor  , Hadia Chaudry  , Nayab Zahid  , Nayab Zulfiqar  , Meherbano Mirza  , Tehreem Fatima  , Nukhba Basra  , Sahar Feroz  , Javeria Abbas  , Mohammad Arslan Naveed  , Hassan Mir  , Umair Humayun  , Ali Raza Chaudhry  
Published: July 2023

To determine the perception and practices regarding COVID-
19 vaccines among the students of Sialkot Medical College, Sialkot.
Custom-Made Ethyl Vinyl Acetate Insoles with Arch Support Could Improve Static Balance in Diabetic Women with Neuropathic Foot
Authors: Hemmati Fatemeh , Tafti Nahid , Nourouzi Ehsan , Turk Sajad Bayat , Karimi Mohammad Taghi , Sharifmoradi Keyvan , Kashani Reza Vahab 
Published: July 2023

Background: Individuals with diabetic neuropathy may experience plantar ulcers and postural instability. Although use of an insole with arch support has the potential to decrease the incidence of plantar ulcers, the choice of proper design and material density concerning postural stability is challenging. The objective of this pilot study was to conduct a preliminary evaluation of the immediate effects of custom-made ethyl vinyl acetate insoles with arch support and Shore A values of 30 or 50 on static balance in patients with diabetes and neuropathic foot/feet.
Methods: Ten women with diabetes participated in this study. Static balance was analyzed while in double-limb standing with eyes closed and eyes open and while standing on a dominant limb with eyes open wearing shoes only and wearing shoes and insoles with Shore A values of 30 and 50.
Results: With insole, the mean values of center of pressure excursions decreased significantly while standing on double limbs with eyes closed. The improvement in static balance was greater while using the insole with greater density; however, the difference was not statistically significant.
Conclusions: An insole with arch support made of ethyl vinyl acetate Shore A of 30 and 50, which could decrease plantar pressure concentration, had no negative effect on the static balance of diabetes. Therefore, further research on the long-term effects of such insoles on the static balance of diabetes is suggested.
Effect of Phosphorus Levels and Micronutrients on Growth and Yield of Babycorn
Authors: Reddy K. Sai Harinath , Singh Shikha , Nawhal Anu 
Published: July 2023

A field experiment was conducted during kharif season (2022) at Crop Research Farm, Department of Agronomy, SHUATS, Prayagraj (U.P.). The treatments consisted of 3 levels of Phosphorous (30, 40, 50 kg ha-1) and 3 levels of micronutrients (Zn-0.5%), (B-0.5%) (Fe-0.5%). The experiment was laid out in Randomized Block Design with 10 treatments and replicated thrice. The results reported that the application of 50kg ha-1 Phosphorous + 0.5% Zinc (treatment -7) recorded maximum plant height (160.7 cm), Maximum plant dry weight (74.60 g plant-1), No. of corns per plant (1.77), corn length (19.3 cm), corn yield (10.06 t ha-1), green fodder yield (28.43 t ha-1). Maximum gross return (1,20501.00 INR ha-1), net return (77,444.00 INR ha-1) and B:C ratio (1.80) were recorded in (treatment -7) that is with 50 kg ha-1 Phosphorous + 0.5% Zinc.
Assessment of US Food and Drug Administration–Approved Digital Medical Devices for Just-in-Time Interventions
Authors: Phi Ngan Thi Thuy , Oikonomidi Theodora , Ravaud Philippe , Tran Viet-Thi 
Published: July 2023

ImportanceJust-in-time interventions (JITIs) are a type of digital therapeutic intervention that combines remote monitoring tools and algorithms to personalize the delivery of specific interventions at the right time. The US Food and Drug Administration (FDA) regulatory approval documents are often the only available source of information on the effectiveness of therapeutic interventions based on these devices.ObjectiveTo systematically review the publicly available information from the FDA on all recently approved medical devices used in JITIs to (1) assess how they operate to deliver JITIs and (2) appraise the evidence supporting their performance and clinical effectiveness.Evidence ReviewTwo reviewers systematically searched the Premarket Notifications (510(k)), Premarket Approvals, De Novo, and Humanitarian Device Exemption databases from January 2019 to December 2021 for all entries associated with devices that monitored patients’ data over time to personalize the delivery of interventions to treat, prevent, or mitigate health conditions or events. They assessed whether the product summaries (1) enabled an understanding of how the device operated to deliver a JITI (eg, the nature, type, and frequency of the monitoring, the nature of the decision algorithm, and the nature and intended receiver of the intervention); (2) informed about the performance and effectiveness of the JITI; and (3) included information on data security and ownership.FindingsIn total, 38 devices were included in this review. These were mainly intended for cardiac conditions (12 [31.6%]), diabetes (10 [26.3%]), and neurological diseases (4 [10.5%]). Monitoring devices ranged from wearable (18 of 28 [64.4%]; eg, smartwatches) to implanted sensors (6 of 28 [21.4%]; eg, inserted electrocardiographic sensors). Only 10 of 38 product summaries (26.3%) allowed a full understanding of how the device operated to deliver a JITI. Similarly, only 12 of 28 (42.9%), 12 of 36 (33.3%), and 5 of 38 (13.2%) reported the assessment of the performance of the monitoring device, assessment of the decision algorithm, and results of clinical studies assessing the effectiveness of the JITI, respectively. Finally, 14 of 36 product summaries (38.9%) included some information on data security, but none included information on data ownership.Conclusion and RelevanceThe results of this systematic review suggest that the information publicly available in the FDA databases on the performance and effectiveness of digital medical devices used in JITIs is heterogeneous.
Reasons for Discontinuation or Change of Selective Serotonin Reuptake Inhibitors in Online Drug Reviews
Authors: Golder Su , Medaglio Dominique , O’Connor Karen , Hennessy Sean , Gross Robert , Gonzalez Hernandez Graciela 
Published: July 2023

ImportanceSelective serotonin reuptake inhibitors (SSRIs) are a commonly prescribed medication class to treat a variety of mental disorders. However, adherence to SSRIs is low, and uncovering the reasons for discontinuation among SSRI users is an important first step to improving medication persistence.ObjectiveTo identify the reasons SSRIs are discontinued or changed, as reported by patients and caregivers in online drug reviews.Design, Setting, and ParticipantsThis qualitative study used natural language processing and machine learning to extract mentions of changes in SSRI intake from 667 drug reviews posted on the online health forum WebMD from September 1, 2007, to August 31, 2021. The type of medication change, including discontinuation, switch to another medication, or dose change and the reason for the change were manually annotated. In each instance in which an adverse event was reported, the event was categorized using Medical Dictionary for Regulatory Activities primary system organ class (SOC) codes, and its relative frequency was compared with that in spontaneous reporting systems maintained by the US Food and Drug Administration and the UK Medicines and Healthcare Products Regulatory Agency.Main Outcomes and MeasuresReasons for SSRI medication change as assessed using SOC codes.ResultsIn total, 667 reviews posted by 659 patients or caregivers (516 [78%] of patients were female; 410 [62%] 25-54 years of age) were identified that indicated a medication change: 335 posts indicated SSRI discontinuation, 188 posts indicated dose change, and 179 posts indicated switched medications. Most authors 625 (95%) were patients. The most common reason for medication discontinuation or switching was adverse events experienced, and the most common reason for dose change was titration. Both uptitration and downtitration were initiated by either a health care professional or patient. The most common adverse events were classified by SOC codes as psychiatric disorders, including insomnia, loss of libido, and anxiety. Compared with those in regulatory data, psychiatric adverse events, adverse events recorded by investigations (mostly weight gain) and adverse events associated with the reproductive system (mostly erectile dysfunction) were reported disproportionately more often.Conclusions and RelevanceThis qualitative study of online drug reviews found that useful information was provided directly by patients or their caregivers regarding their medication behavior, specifically, information regarding SSRI treatment changes that may inform interventions to improve adherence. These findings suggest that these reported adverse events may be associated with SSRI persistence and that people may feel more inclined to report such events on social media than to clinicians or regulatory agencies.
Workforce Attrition Among Male and Female Physicians Working in US Academic Hospitals, 2014-2019
Authors: Chen Ya-Wen , Orlas Claudia , Kim Tommy , Chang David C. , Kelleher Cassandra M. 
Published: July 2023

ImportanceRetaining female physicians in the academic health care workforce is necessary to serve the needs of sociodemographically diverse patient populations.ObjectiveTo investigate differences in rates of leaving academia between male and female physicians.Design, Setting, and ParticipantsThis cohort study used Care Compare data from the Centers for Medicare &amp;amp; Medicaid Services for all physicians who billed Medicare from teaching hospitals from March 2014 to December 2019, excluding physicians who retired during the study period. Data were analyzed from November 11, 2021, to May 24, 2022.ExposurePhysician gender.Main Outcome and MeasuresThe primary outcome was leaving academia, which was defined as not billing Medicare from a teaching hospital for more than 1 year. Multivariable logistic regression was conducted adjusting for physician characteristics and region of the country.ResultsThere were 294 963 physicians analyzed (69.5% male). The overall attrition rate from academia was 34.2% after 5 years (38.3% for female physicians and 32.4% for male physicians). Female physicians had higher attrition rates than their male counterparts across every career stage (time since medical school graduation: &amp;lt;15 years, 40.5% vs 34.8%; 15-29 years, 36.4% vs 30.3%; ≥30 years, 38.5% vs 33.3%). On adjusted analysis, female physicians were more likely to leave academia than were their male counterparts (odds ratio, 1.25; 95% CI, 1.23-1.28).Conclusions and RelevanceIn this cohort study, female physicians were more likely to leave academia than were male physicians at all career stages. The findings suggest that diversity, equity, and inclusion efforts should address attrition issues in addition to recruiting more female physicians into academic medicine.
Mimicking Antioxidases and Hyaluronan Synthase: A Zwitterionic Nanozyme for Photothermal Therapy of Osteoarthritis
Authors: Yu Peng , Li Yanyan , Sun Hui , Zhang Hongbo , Kang Han , Wang Peng , Xin Qiangwei , Ding Chunmei , Xie Jing , Li Jianshu 
Published: July 2023

AbstractRestoring joint homeostasis is crucial for relieving osteoarthritis (OA). Current strategies are limited to unilateral efforts in joint lubrication, inhibition of inflammation, free radicals scavenging, and cartilage regeneration. Herein, by modifying molybdenum disulfide (MoS2) with Mg2+‐doped polydopamine and coating with polysulfobetaines, a dual‐bionic photothermal nanozyme (MPMP) is constructed to mimic antioxidases/hyaluronan synthase for OA therapy. Photothermally enhanced lubrication lowers the coefficient of friction (0.028) in the early stage of OA treatment. The antioxidases‐mimicking properties of MPMP nanozyme contribute to eliminating reactive oxygen and nitrogen species (ROS/RNS) (over 90% of scavenging ratio for H2O2/·OH/O·2–/DPPH/ABTS+) and supplying O2. With NIR irradiation, the MPMP nanozyme triggers thermogenesis (upregulating HSP70 expression) and Mg2+ release, which promotes the chondrogenesis in inflammatory conditions by deactivating NF‐κB/IL‐17 signaling pathways and enhancing MAPK signaling pathway. Benefiting from HSP70 and Mg2+, MPMP‐NIR shows HAS‐mimicking activity to increase the intracellular (twofold) and extracellular (3.12‐fold) HA production. Therefore, MPMP‐NIR demonstrates superior spatiotemporally therapeutic effect on OA in mice model, in terms of osteophytes (83.41% of reduction), OARSI scores (88.57% of reduction), and ACAN expression (2.70‐fold of increment). Hence, insights into dual‐bionic nanozymes can be a promising strategy for OA therapy or other inflammation‐related diseases.
Thermoplastic Elastomers for Wireless, Skin‐Interfaced Electronic, and Microfluidic Devices
Authors: Wu Yunyun , Liu Claire , Lapiere Mia , Ciatti Joanna L. , Yang Da Som , Berkovich Jaime , Model Jeffrey B. , Banks Anthony , Ghaffari Roozbeh , Chang Jan‐Kai , Nuzzo Ralph G. , Rogers John A. 
Published: July 2023

AbstractWireless, skin‐interfaced electronic and microfluidic devices have the potential to replace wired, bulky, and cumbersome technologies for personal and clinical health monitoring, allowing care to extend from hospital settings to the home. For use on skin, these devices commonly employ silicone‐based thermoset elastomers (TSEs) as layers that encapsulate the electronics or serve as molded microchannels for biofluid (e.g., sweat) capture, storage, and analysis. Barriers to commercial adoption of such devices include difficulties in use of these elastomers in conventional practices for mass manufacturing. Their relatively high cost and inability to allow for recycling represent additional disadvantages. By contrast, thermoplastic elastomers (TPEs) are fully compatible with industrial‐scale manufacturing processes, low in cost, and recyclable. Like TSEs, TPEs are soft, stretchable, flexible, and optically transparent, while possessing other properties well‐suited for applications in wireless, skin‐interfaced devices. Herein, the characteristics, processing, and application techniques for three commercially available TPEs, including two thermoplastic polyurethanes as encapsulation layers for a wireless skin hydration sensor and one thermoplastic styrenic block copolymer for a microfluidic sweat analysis platform, are reported. The results demonstrate that TPEs can be effectively integrated into these classes of devices, as a compelling alternative to TSEs, as a mass‐manufacturable, sustainable materials option.
Comparative floral development in male and female plants of Palmer amaranth (Amaranthus palmeri)
Authors: Wu Wenzhuo , Jernstedt Judy , Mesgaran Mohsen B. 
Published: July 2023

AbstractPremiseCharacterizing the developmental processes in the transition from hermaphroditism to unisexuality is crucial for understanding floral evolution. Amaranthus palmeri, one of the most devastating weeds in the United States, is an emerging model system for studying a dioecious breeding system and understanding the biological traits of this invasive weed. The objectives of this study were to characterize phases of flower development in A. palmeri and compare organogenesis of flower development in female and male plants.MethodsFlower buds from male and female plants were dissected for light microscopy. Segments of male and female inflorescences at different stages of development were cut longitudinally and visualized using scanning electron microscopy.ResultsPistillate flowers have two to three styles, one ovary with one ovule, and five obtuse tepals. Staminate flowers have five stamens with five acute tepals. Floral development was classified into 10 stages. The distinction between the two flower types became apparent at stage four by the formation of stamen primordia in staminate flowers, which developed female and male reproductive organs initially, as contrasted to pistillate flowers, which produced carpel primordia only. In staminate flowers, the putative carpel primordia changed little in size and remained undeveloped.ConclusionsTiming of inappropriate organ termination varies across the two sexes in A. palmeri. Our study suggests that the evolution of A. palmeri from a cosexual ancestral state to complete dioecy is still in progress since males exhibited transient hermaphroditism and females produced strictly pistillate flowers.
Profile of a flower: How rates of morphological evolution drive floral diversification in Ericales and angiosperms
Authors: Herting Julian , Schönenberger Jürg , Sauquet Hervé 
Published: July 2023

AbstractPremiseRecent studies of floral disparity in the asterid order Ericales have shown that flowers vary strongly among families and that disparity is unequally distributed between the three flower modules (perianth, androecium, gynoecium). However, it remains unknown whether these patterns are driven by heterogeneous rates of morphological evolution or other factors.MethodsHere, we compiled a data set of 33 floral characters scored for 414 species of Ericales sampled from 346 genera and all 22 families. We conducted ancestral state reconstructions using an equal‐rates Markov model for each character. We estimated rates of morphological evolution for Ericales and for a separate angiosperm‐wide data set of 19 characters and 792 species, creating “rate profiles” for Ericales, angiosperms, and major angiosperm subclades. We compared morphological rates among flower modules within each data set separately and between data sets, and we compared rates among angiosperm subclades using the angiosperm data set.ResultsThe androecium exhibits the highest evolutionary rates across most characters, whereas most perianth and gynoecium characters evolve more slowly in both Ericales and angiosperms. Both high and low rates of morphological evolution can result in high floral disparity in Ericales. Analyses of an angiosperm‐wide floral data set reveal that this pattern appears to be conserved across most major angiosperm clades.ConclusionsElevated rates of morphological evolution in the androecium of Ericales may explain the higher disparity reported for this floral module. Comparing rates of morphological evolution through rate profiles proves to be a powerful tool in understanding floral evolution.
Late‐Stage Aryl C−H Bond Cyclopropenylation with Cyclopropenium Cations
Authors: Tu Hang‐Fei , Jeandin Aliénor , Bon Corentin , Brocklehurst Cara , Lima Fabio , Suero Marcos G. 
Published: July 2023

AbstractHerein, we disclose the first regio‐, site‐ and chemoselective late‐stage (hetero)aryl C−H bond cyclopropenylation with cyclopropenium cations (CPCs). The process is fast, operationally simple and shows an excellent functional group tolerance in densely‐functionalized drug molecules, natural products, agrochemicals and fluorescent dyes. Moreover, we discovered that the installation of the cyclopropene ring in drug molecules could not only be used to shield against metabolic instability but also as a synthetic tool to reach medicinally‐relevant sp3‐rich scaffolds exploiting the highly‐strained nature of the cyclopropene ring with known transformations.