bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marshbird response to herbicide control of cattail in northwestern Minnesota
Authors: Hill Nina M. , Johnson Douglas H. , Cooper Thomas R. , Archer Althea A. , Andersen David E. 
Published: August 2023

AbstractWetlands provide essential habitat for a wide variety of wildlife species. In the once wetland‐rich Prairie Pothole Region and adjacent areas of central North America, many wetlands have been converted to agricultural production. Many remaining wetlands experience ecological change via the invasion and spread of non‐native plant species, such as non‐native narrowleaf (Typha angustifolia) and hybrid cattail (Typha x glauca), which spread aggressively and displace native vegetation, especially in large, impounded wetlands. Management of wetlands in these landscapes often includes broad‐scale herbicide application intended to break up mats of cattail and restore areas to more wildlife‐friendly conditions. Although restoration of wildlife habitat is a common goal of such management, marshbird response to invasive cattail control is poorly understood. To evaluate the effects of cattail management on wetland wildlife, we conducted standardized call‐broadcast surveys for 5 species of marshbirds at 9 study sites that included survey locations associated with areas treated with herbicide and paired areas not treated with herbicide in wetland impoundments in northwestern Minnesota, USA, using a before‐after, control‐impact study design. We surveyed American bitterns (Botaurus lentiginosus), least bitterns (Ixobrychus exilis), pied‐billed grebes (Podilymbus podiceps), soras (Porzana carolina), and Virginia rails (Rallus limicola) during the breeding season prior to herbicide application (late summer and early autumn of 2015) and during the 3 breeding seasons after herbicide application (2016–2018). We modeled species counts using a generalized linear mixed model with year‐by‐treatment interactions as fixed effects and site as a random effect. Before herbicide application, expected mean counts did not differ between treatment and control survey locations. Three years post‐treatment, we detected significant increases in expected mean counts at treatment compared to control survey locations for soras (t193 = −3.373, P = 0.020) and Virginia rails (t193 = −3.167, P = 0.037), and point estimates for all species except least bittern were higher at treatment survey locations. Overall, our results suggest that these marshbird species responded positively to herbicide control of invasive cattail and that breeding marshbirds in these and similar wetland systems may experience positive population response over a period of at least 3 years following treatment.
18F‐FDG‐PET/CT imaging in diagnostic workup of pediatric precursor B‐cell lymphoblastic lymphoma
Authors: Kroeze Emma , Padilla Laura Arias , Burkhardt Birgit , Attarbaschi Andishe , von Mersi Hannah , Kebudi Rejin , Nievelstein Rutger A. J. , Tolboom Nelleke , Hagleitner Melanie M , Kuiper Roland P , Beishuizen Auke , Loeffen Jan L. C. 
Published: August 2023

Abstract18F‐fluorodeoxyglucose‐positron emission tomography/computed tomography (PET/CT) imaging is currently not used in standard diagnostics for B‐cell precursor lymphoblastic lymphoma (BCP‐LBL), and it is unknown whether PET/CT imaging would lead to agreement between detection of lesions with the gold standard imaging methods. Therefore, we performed a retrospective cohort study in which we included 32 pediatric BCP‐LBL patients and determined localizations by reviewing local imaging reports. There was a disagreement between protocol‐based imaging and PET/CT in 59% of the patients, and the discrepancies mostly comprise of additional lesions detected with PET/CT, typically in lymph node and bone or the absence of bone marrow involvement with PET/CT. If PET/CT was leading in determining definite stage of disease, this would lead to a different stage and therapy branch in 31% and 28% of the patients, respectively.
Factor activity levels and bleeding scores in pediatric hemophilia carriers enrolled in the ATHNdataset
Authors: Puetz John , Hu Brian 
Published: August 2023

AbstractBackgroundMultiple studies have now shown that a significant proportion of hemophilia carriers meet the criteria for having hemophilia and/or report abnormal bleeding. However, to date, investigations of hemophilia carriers have almost exclusively involved women over 18 years of age. Little is known about factor activity levels and bleeding scores in carriers during childhood. We queried a large deidentified database of subjects with bleeding disorders residing in the United States to determine factor activity levels and bleeding scores.ProceduresThe ATHNdataset was queried for hemophilia carriers under 18 years of age. Collected information included demographics, factor activity levels, and bleeding scores.ResultsOver 700 carriers in the pediatric age group were identified, of which 626 submitted factor activity levels. Nearly half had factor activity levels less than 40 IU/dL, thereby meeting criteria for having hemophilia. Of those reporting bleeding scores, only 13.5% reported an abnormal bleeding score for age. The proportion reporting abnormal bleeding scores was higher in those with factor levels less than 40 IU/dL (23%) than those greater than 40 IU/dL (9.7%).ConclusionsThe proportion of pediatric carriers with hemophilia was double of that previously reported for adults. Of those with hemophilia reporting a bleeding score, the majority (77%) did not report an abnormal bleeding score for age. However, nearly 10% of pediatric carriers not meeting criteria for having hemophilia reported abnormal bleeding scores for age. Similar results are reported in adults suggesting that factor activity levels may not be predictive of bleeding symptoms in carriers.
A systematic review of the prevalence of pathogenic or likely pathogenic germline variants in individuals with FOXO1 fusion‐positive rhabdomyosarcoma
Authors: Freycon Claire , Lupo Philip J , Witkowski Leora , Budd Crystal , Foulkes William D. , Goudie Catherine 
Published: August 2023

AbstractSeveral cancer predisposition syndromes (CPS) are reported to predispose to rhabdomyosarcoma, most frequently in children with embryonal rhabdomyosarcoma. There are lingering questions over the role of CPS in individuals with alveolar rhabdomyosarcoma (ARMS), which are frequently driven by FOXO1 fusion oncoproteins. We conducted a systematic review to identify patients with FOXO1 fusion‐positive ARMS (FP‐ARMS) who underwent germline DNA sequencing. We estimated the prevalence of pathogenic/likely pathogenic (P/LP) variants in cancer predisposing genes (CPGs) and of CPSs. We included 19 publications reporting on 191 patients with FP‐ARMS. P/LP variants in CPGs were identified in 26/191 (13.6%) patients, nine (4.9%) of which were associated with a CPS diagnosis. Evidence for causal associations between CPSs and FP‐ARMS could not be assessed with available data from this review. Only one patient was affected with a CPS known to predispose to rhabdomyosarcoma, Li–Fraumeni syndrome. Typical CPS associations with rhabdomyosarcoma are rare, but not nonexistent, in patients with FP‐ARMS. FOXO1 fusion status, alone, is insufficient for clinicians to rely on to distinguish between patients with/without CPS.
Case study: Investigating the effect of the A2 Pasquill atmospheric condition on the dispersion modeling of heavy gases
Authors: Nathani Alia , Ong Chee Seang 
Published: August 2023

AbstractThis study provides a defensible argument for the inclusion of the A2 Pasquill weather parameter in dispersion modeling, in addition to the typical F2 and D5. The A2 parameter conservatively models gas releases that concentrate at ground level, thus allowing for a more robust design of vent heights, surrounding structures/equipment and safety measures. For this investigation, 12 case studies of common hydrocarbon and aromatic gas mixtures were developed in PHAST (Process Hazard Analysis Software Tool) version 8.6. Each case varied in temperature, release pressure (velocity), and molecular weight (MW) to simulate dense gases likely to tend toward ground level. Subsequently, each case study was modeled with the Pasquill Atmospheric Stability Classes, A2, D5, and F2, to visualize the dispersion of dense gases under different weather conditions and evaluate which weather parameter would be most inclusive of high‐severity scenarios. Results demonstrate that dense (colder than dew point, heavy, pressurized) gases yield highest ground‐level concentrations using the A2 atmospheric condition, and the further the release temperature falls below the mixture's dew point, the greater the mixture concentration at ground level. Consequence modeling recommendations are discussed, and specific gas properties are addressed that necessitate using a model that is conservative in its estimation of ground‐level concentrations.
Population pharmacokinetics of ivermectin after mass drug administration in lymphatic filariasis endemic communities of Tanzania
Authors: Fimbo Adam M. , Mlugu Eulambius M. , Kitabi Eliford Ngaimisi , Kulwa Gerald S. , Iwodyah Mohammed A. , Mnkugwe Rajabu Hussein , Kunambi Peter P. , Malishee Alpha , Kamuhabwa Appolinary A. R. , Minzi Omary M. , Aklillu Eleni 
Published: August 2023

AbstractIvermectin (IVM) is a drug of choice used with albendazole for mass drug administration (MDA) to halt transmission of lymphatic filariasis. We investigated IVM pharmacokinetic (PK) variability for its dose optimization during MDA. PK samples were collected at 0, 2, 4, and 6 h from individuals weighing greater than 15 kg (n = 468) receiving IVM (3‐, 6‐, 9‐, or 12 mg) and ALB (400 mg) during an MDA campaign in Tanzania. Individual characteristics, including demographics, laboratory/clinical parameters, and pharmacogenetic variations were assessed. IVM plasma concentrations were quantified by liquid‐chromatography tandem mass spectrometry and analyzed using population‐(PopPK) modeling. A two‐compartment model with transit absorption kinetics, and allometrically scaled oral clearance (CL/F) and central volume (Vc/F) was adapted. Fitting of the model to the data identified 48% higher bioavailability for the 3 mg dose compared to higher doses and identified a subpopulation with 97% higher mean transit time (MTT). The final estimates for CL/F, Vc/F, intercompartment clearance, peripheral volume, MTT, and absorption rate constant for a 70 kg person (on dose other than 3 mg) were 7.7 L/h, 147 L, 20.4 L/h, 207 L, 1.5 h, and 0.71/h, respectively. Monte‐Carlo simulations indicated that weight‐based dosing provides comparable exposure across weight bands, but height‐based dosing with capping IVM dose at 12 mg for individuals with height greater than 160 cm underdoses those weighing greater than 70 kg. Variability in IVM PKs is partly explained by body weight and dose. The established PopPK model can be used for IVM dose optimization. Height‐based pole dosing results in varying IVM exposure in different weight bands, hence using weighing scales for IVM dosing during MDA is recommended.
PLPF‐VSLAM: An indoor visual SLAM with adaptive fusion of point‐line‐plane features
Authors: Yan Jinjin , Zheng Youbing , Yang Jinquan , Mihaylova Lyudmila , Yuan Weijie , Gu Fuqiang 
Published: August 2023

AbstractSimultaneous localization and mapping (SLAM) is required in many areas and especially visual‐based SLAM (VSLAM) due to the low cost and strong scene recognition capabilities conventional VSLAM relies primarily on features of scenarios, such as point features, which can make mapping challenging in scenarios with sparse texture. For instance, in environments with limited (low‐even non‐) textures, such as certain indoors, conventional VSLAM may fail due to a lack of sufficient features. To address this issue, this paper proposes a VSLAM system called visual SLAM that can adaptively fuse point‐line‐plane features (PLPF‐VSLAM). As the name implies, it can adaptively employ different fusion strategies on the PLPF for tracking and mapping. In particular, in rich‐textured scenes, it utilizes point features, while in non‐/low‐textured scenarios, it automatically selects the fusion of point, line, and/or plane features. PLPF‐VSLAM is evaluated on two RGB‐D benchmarks, namely the TUM data sets and the ICL_NUIM data sets. The results demonstrate the superiority of PLPF‐VSLAM compared to other commonly used VSLAM systems. When compared to ORB‐SLAM2, PLPFVSLAM achieves an improvement in accuracy of approximately 11.29%. The processing speed of PLPF‐VSLAM outperforms PL(P)‐VSLAM by approximately 21.57%.
Urban sustainability as a social function of the city: Strategic correlation based on Brazilian legislation with the new urban agenda and sustainable development goals
Authors: Dias Felipe Teixeira , Leite Marcos Esdras , Fernandes Edilaine Neves , Cembranel Priscila , Rita Raíssa Maria , de Andrade Guerra José Baltazar Salgueirinho Osório 
Published: August 2023

AbstractGlobal cities are the arena of several socioenvironmental phenomena. To alleviate the disparities and catastrophes arising from the rapid process of urbanization, several nations have begun to pursue a common aim: sustainable development. In this regard, goals and parameters have been established by the United Nations (UN) to encourage debates aimed at the protection of the planet. Since 1930, discussions have sought to promote actions and rethink urban planning, for example, at the International Congress of Modern Architecture, which produced the Athens Charter. In this context, the study reported herein correlates the New Urban Agenda, which systematizes the UN Sustainable Development Goals (SDGs) together with the social functions of a city, a concept instigated by international legislation, charters and research to consolidate urban sustainability. As a proposed methodology, this study systemizes integrative data processing, with an applicable approach. In addition, a systematic analysis of the literature was carried out to create definitions and concepts on this theme. As a result, it was verified that social functions can and should integrate global urban policies, particularly when articulated with the SDGs and the New Urban Agenda.
The Cleanroom‐Free, Cheap, and Rapid Fabrication of Nanoelectrodes with Low zM Limits of Detection
Authors: Maroli Gabriel , Abarintos Vernalyn , Piper Andrew , Merkoçi Arben 
Published: August 2023

AbstractNanoscale electrodes have been a topic of intense research for many decades. Their enhanced sensitivities, born out of an improved signal‐to‐noise ratio as electrode dimensions decrease, make them ideal for the development of low‐concentration analyte sensors. However, to date, nanoelectrode fabrication has typically required expensive equipment and exhaustive, time‐consuming fabrication methods that have rendered them unsuitable for widespread use and commercialization. Herein, a method of nanoband electrode fabrication using low cost materials and equipment commonly found in research laboratories around the world is reported. The materials' cost to produce each nanoband is less than €0.01 and fabrication of a batch takes less than 1 h. The devices can be made of flexible plastics and their designs can be quickly and easily iterated. Facile methods of combining these nanobands into powerful devices, such as complete three‐electrode systems, are also displayed. As a proof of concept, the electrodes are functionalized for the detection of a DNA sequence specific to SARS‐CoV‐2 and found to display single molecule sensitivity.
Robust Cellulose Nanocrystal‐Based Self‐Assembled Composite Membranes Doped with Polyvinyl Alcohol and Graphene Oxide for Osmotic Energy Harvesting
Authors: Zhang Xin , Li Minmin , Zhang Fusheng , Li Qiongya , Xiao Jie , Lin Qiwen , Qing Guangyan 
Published: August 2023

AbstractOsmotic energy from the salinity gradients represents a promising energy resource with stable and sustainable characteristics. Nanofluidic membranes can be considered as powerful alternatives to the traditional low‐performance ion exchange membrane to achieve high‐efficiency osmotic energy harvesting. However, the development of a highly efficient and easily scalable core membrane component from low‐cost raw materials remains challenging. Here, a composite membrane based on the self‐assembly of cellulose nanocrystals (CNCs) with polyvinyl alcohol (PVA) and graphene oxide (GO) nanoflakes as additives is developed to provide a solution. The introduction of soft PVA polymer significantly improves the mechanical strength and water stability of the composite membrane by forming a nacre‐like structure. Benefiting from the abundant negative charges of CNC nanorods and GO nanoflakes and the generated network nanochannels, the composite membrane demonstrates a good cation‐selective transport capacity, thus contributing to an optimal osmotic energy conversion of 6.5 W m−2 under a 100‐fold salinity gradient and an exemplary stability throughout 25 consecutive days of operation. This work provides an option for the development of nanofluidic membranes that can be easily produced on a large scale from well‐resourced and sustainable biomass materials for high‐efficiency osmotic energy conversion.
Constructing High‐Performance Ternary Device Using Analogous Polymer Donors
Authors: Fang Yu , Deng Xiangmeng , Lu Jiayong , Huang Bin , Chen Shanshan , Liu Kunming , Zhang Jialin , Jeong Seonghun , Yang Changduk , Liu Jinbiao 
Published: August 2023

AbstractBoth ternary copolymerization and ternary blending are effective methods to fine‐tune polymer structure and manipulate thin‐film morphology to improve device performance. In this work, three D‐A‐A‐A (D: donor, A: acceptor) terpolymer donors (FY1, FY2, and FY3) are synthesized by introducing BDD (1,3‐bis(2‐ethylhexyl)‐5,7‐di(thiophen‐2‐yl)benzo[1,2‐c:4,5‐c']dithiophene‐4,8‐dione) units into the D–A alternating copolymer PM6 backbone. Owing to the promoted conjugated planarity and excellent absorption of BDD, the obtained terpolymers display an extended absorption range and enhanced π–π stacking orientation, which is a promising third component in ternary device. As a result, the optimal FY1:PM6:BTP‐eC9‐based ternary device afforded an impressive power conversion efficiency (PCE) as high as 18.52%, owing to the efficient charge transport, negligible energy loss, and suitable domain size. The result provides an efficient method to obtain high‐performance polymer solar cells by using analogous polymer donors in ternary device.
Building Negative‐Thermal‐Expansion Protective Layers on the Grain Boundary of Ni‐rich Cathodes Enables Safe and Durable High Voltage Lithium‐Ion Batteries
Authors: Nie Wei , Tang Yongfu , Cheng Hongwei , Tian Feng , Sun Qiangchao , Lu Xionggang , Zhao Yufeng 
Published: August 2023

AbstractNi‐rich layered oxide cathode materials demonstrate high energy densities for Li‐ion batteries, but the electrochemically driven thermal runaway and mechanical degradation remain their long‐standing challenges in practical applications. Herein, it presents a novel ZrV2O7 (ZVO) coating with negative thermal expansion properties along the secondary particles and primary particle grain boundaries (GBs), to simultaneously enhance the structural and thermal stability of LiNi0.8Co0.1Mn0.1O2 (NCM811). It unveils that, such an architecture can significantly enhance the electronic conductivity, suppress the microcracks of GBs, alleviate the layered to spinel/rock‐salt phase transformation, and meanwhile relieve the lattice oxygen loss by increasing the oxygen vacancy formation energy increased (1.43 vs 1.90 eV). Consequently, the ZVO‐coated NCM811 material demonstrates a remarkable cyclability with 86.5% capacity retention after 100 cycles, and an outstanding rate performance of 30 C under a high‐voltage of 4.6 V, outperforming the state‐of‐the‐art literature. More importantly, the Li+ transportation can be readily blocked at 120 °C by the negative‐thermal‐expansion ZVO coating, thus avoiding the high‐temperature thermal runaway.
Clinical findings, treatment and outcome in cats diagnosed with precursor‐targeted immune‐mediated anaemia in a referral hospital in the UK: 30 cases (2010–2021)
Authors: Maldonado‐Moreno Alba , Seth Mayank , Monti Paola , Miller Rachel 
Published: August 2023

AbstractAimsThis retrospective study aimed to report clinical findings, treatment response and survival in cats diagnosed with precursor‐targeted immune‐mediated anaemia (PIMA) in a referral hospital in the UK.MethodsFeline cases diagnosed with presumed PIMA between January 2010 and February 2021 were retrospectively recruited. Signalment, clinical signs, diagnostic tests, treatment and outcome were recorded. Descriptive analytics were performed. Outcomes were documented according to survival to discharge, 30‐day survival, total survival time, response to immunosuppressive treatment and frequency of relapses.ResultsThirty cats met the inclusion criteria. A higher prevalence of females (19/30) was identified (p = 0.001). Most cats (25/30) presented with haematocrit below 0.15 L/L. Concurrent cytopenias occurred in 18 of 30 cats. Bone marrow diagnosis was erythroid hyperplasia in 24 of 30 cases. Survival to discharge was documented in 26 of 30 cats, of which 23 survived more than 30 days since diagnosis. Initial treatment included blood products (26/30) and prednisolone (26/30) or prednisolone with ciclosporin (3/30); 18 of 30 cats responded to treatment, with a normal haematocrit at a mean of 28 days. The initial haematocrit and the presence of concurrent cytopenia were not statistically different between responders and non‐responders. The median survival time was 140 days (range 1–3930 days).Conclusions and relevanceThe treatment response rate of feline PIMA was high (60%), with a mortality rate of 23% over the 30 days following diagnosis. Relapses occur frequently (77%) but the response rate after treatment modification was high (76%) and therefore ongoing treatment may be justified at that point. Long survival times (up to 3930 days) can be achieved.
Anesthesia for office‐based facial plastic surgery procedures
Authors: Bharadwaj Suhas , Dougherty William 
Published: August 2023

AbstractObjectiveThe objective of this study is to provide a state‐of‐the‐art review on the use of anesthetics for in‐office facial plastic procedures.MethodsA search was performed on PubMed, Embase, Web of Science, and Cochrane Review using the keywords “anesthesia,” “office‐based procedures,” “local anesthesia,” “facial plastics,” “oral sedation,” “moderate sedation,” and “deep sedation.”Results and ConclusionsOver the past few decades, the shift toward in‐office invasive procedures has increased patient convenience and decreased hospital resource utilization. Many tools exist to reduce patient anxiety and discomfort in an office‐based setting. With proper patient selection and technique, facial plastic surgeons can adequately anesthetize patients to perform Mohs reconstruction, cutaneous excisions, blepharoplasty, face‐lifts, and other in‐office procedures.