bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chronic myelogenous leukemia presenting with Morel Lavallée lesion: A case report of a rare presentation
Authors: Mohamed Sara S. I. , Qasim Hana Mahmoud , Mahfouz Ahmed , Osman Maab A. , Ahmed Ashraf O. E. , Al‐Azewi Safa H. , Yassin Mohamad A. , Fareed Shehab 
Published: December 2022

AbstractChronic myelogenous leukemia is a myeloproliferative neoplasm characterized by the BCR‐ABL1 fusion gene and the development of the Philadelphia chromosome, which leads to an increase in granulocytes and bone marrow myeloid precursors in the blood, it can lead to many possible complications depending on the disease stage at the time of diagnosis. The Morel‐Lavallée lesion (MLL) is a closed traumatic soft‐tissue degloving injury, that results from the separation of the hypodermis from the underlying fascia, with resultant hemo‐lymphatic fluid collection between the tissue layers. We report a case of a 48‐year‐old male patient, with no chronic illnesses, who presented with 2 weeks history of posterior chest wall pain and swelling. Initial investigation showed a white blood cell count of 364.4 × 103/μl. Bone marrow pathology report findings were consistent with chronic myeloid leukemia (CML), and the BCR‐ABL test came positive. CT chest with contrast showed a large chest wall lesion, suggestive of a Morel‐Lavallee lesion. Ultrasound‐guided aspiration of the lesion yielded 20 mm of fluid from the thick hematoma. Histopathology of the fluid showed Necrotic debris with mixed inflammation. Patient's condition improved, and he was discharged on Dasatinib with follow‐up in hematology and surgery clinics.
Essential Role of Pulping Route on Thermal Stability Performance of Rice Straw‐Based Nanocelluloses
Authors: Basta Altaf H. , Lotfy Vivian F. 
Published: December 2022

AbstractThere is a strong interest in production of thermally stable nanocelluloses for further applications. Despite the enormous success achieved in preparing cellulose nanocrystals (CNCs) by acid catalyst technique, these products remain a major challenge due to the lack of thermal stability which till now could not be solved. This work deals with assessing the role of alkali, neutral, acid, and organosolvent pulping agents on thermal stability performances of produced rice straw (RS)‐based CNCs. This property was estimated by thermogravimetric analysis. The data obtained indicated that employing a pulping to RS > 4.75 mm with sodium hydroxide in the presence of anthraquinone‐sodium borohydride can help address these challenges by providing CNCs with highest activation energy as well as a lower aspect length‐to‐width ratio according to transmission electron microscopy images.
A Nitrogen‐Doped Porous Carbon Supported Copper Catalyst from a Scalable One‐Step Method for Efficient Carbon Dioxide Electroreduction
Authors: Vijayakumar Amruthalakshmi , Zhao Yong , Wang Kezhong , Chao Yunfeng , Chen Haiqun , Wang Caiyun , Wallace Gordon G. 
Published: December 2022

AbstractIn this work, a scalable one‐step glucose blowing method has been used to prepare a porous N‐doped carbon supported Cu nanoparticles (Cu‐NC) composite catalyst for CO2 electroreduction. This Cu‐NC catalyst demonstrates efficient catalytic activity for CO2‐to‐C1 product (CO and formate) conversion, with a high efficiency of 69 % at an overpotential of 590 mV. The excellent catalytic activity is correlated to the structure of this composite and the N‐species (pyridinic and graphitic nitrogen) in the carbonaceous matrix that may promote the CO2 adsorption and subsequent formation of reduction reaction intermediates and products.
Electrochemical Synthesis of 5‐Benzylidenebarbiturate Derivatives and Their Application as Colorimetric Cyanide Probe
Authors: El‐Dash Yara S. , Mahmoud Amr M. , El‐Mosallamy Sally S. , El‐Nassan Hala B. 
Published: December 2022

AbstractA highly efficient, fast, catalyst‐free, and atom economical method was developed for the synthesis of 5‐benzylidenebarbiturates. Thus, reacting barbituric acid and aldehydes in water as a green solvent under electrochemical conditions afforded the synthesis of the target compounds in six minutes and in highly pure forms. The effects of solvent, reaction time, temperature, electrolyte, and electrode material were studied to optimize the reaction conditions. The scope of the reaction was broadened by the synthesis of 5‐(arylidene)barbiturate derivatives 3 a–3 q using different aldehydes. Calculation of the green chemistry metrics proved the efficiency of the reaction in terms of E‐factor, mass intensity, mass productivity, and reaction mass efficiency. Compound 3 g [5‐(4‐(dimethylamino)benzylidene) barbiturate] was used for the colorimetric detection of cyanide ion over dynamic linear range 1–25 μM with limit of detection (LOD) of 0.86 μM.
LiNi0.5Mn1.5O4 Thin Films Grown by Magnetron Sputtering under Inert Gas Flow Mixtures as High‐Voltage Cathode Materials for Lithium‐Ion Batteries
Authors: Darjazi Hamideh , Madinabeitia Iñaki , Zarrabeitia Maider , Gonzalo Elena , Acebedo Begoña , Javad Rezvani S. , Fernández‐Carretero Francisco José , Nobili Francesco , García‐Luis Alberto , Muñoz‐Márquez Miguel Ángel 
Published: December 2022

AbstractDelivering a commercial high‐voltage spinel LiNi0.5Mn1.5O4 (LNMO) cathode electrode for Li‐ion batteries would result in a significant step forward in terms of energy density. However, the structural ordering of the spinel and particle size have considerable effects on the cathode material's cyclability and rate capability, which are crucial challenges to address. Here, a novel mid‐frequency alternating current dual magnetron sputtering method was presented, using different Ar‐N2 gas mixtures ratios for the process gas to prepare various LNMO thin films with highly controlled morphology and particle size; as determined from X‐ray diffraction, Raman spectroscopy and electron microscopy. It resulted in enhanced cycling and rate performance. This processing method delivered N‐containing LNMO thin film electrodes with up to 15 % increased discharge capacity at 1 C (120 mAh g−1) with respect to standard LNMO (grown under only Ar gas flow) thin film electrodes, along with outstanding rate performance up to 10 C (99 mAh g−1) in the operating voltage window 3.5–4.85 V vs. Li+/Li. Besides, electrochemical impedance spectroscopy results showed that the intricate phase transitions present in standard LNMO electrodes were almost suppressed in N‐containing LNMO thin films grown under different Ar‐N2 gas flow mixtures.
Understanding PFOS Adsorption on a Pt Electrode for Electrochemical Sensing Applications
Authors: Gogoi Pratahdeep , Yao Yu , Li Yuguang C. 
Published: December 2022

AbstractPer‐ and polyfluroalkyl substances (PFAS) are drawing increasing attention in the research community due to their wide spread applications and their toxicity to animals and humans. Effective early detection method of PFAS chemicals in aqueous environment is important to reduce exposure and mitigate the potential toxic effects. This study focuses on the electrochemical detection of per‐fluoro octane sulfonate (PFOS) with differential pulse voltammetry and electrochemical impedance spectroscopy on a bare platinum electrode. We observe three distinct regions of adsorption behaviors with respect to PFOS concentration from 0–1000 nM, reflecting changes in the modes of adsorption due to different adsorbate‐adsorbate interactions on a bare electrode. The adsorption isotherm constant for PFOS adsorption on a Pt electrode is calculated to be 1.6×1012 cm3 mol−1 from fitting the electrochemical data with a modified Langmuir isotherm model.
Ni3Se4 Nanostructure as a Battery‐type Positive Electrode for Hybrid Capacitors
Authors: Reddy Inta Harish , Koppisetti Heramba V. S. R. M. , Ghosh Sourav , Roy Avishek , Mahalingam Venkataramanan 
Published: December 2022

AbstractBattery‐type supercapacitors have drawn significant attention due to their high charge storage ability resulted from the combined surface and intercalation redox phenomenon. In this regard, nickel chalcogenides are expected to deliver high specific capacity accompanied by their dominant battery‐type supercapacitor features. Herein, we have developed a facile one step solvothermal route to prepare pure phase Ni3Se4 nanostructures and attempted to understand the synthetic factors such as solvent and Ni/Se ratio on the formation of Ni3Se4 phase. The obtained Ni3Se4 nanostructures were subjected to the supercapacitor performance evaluation by loading them onto carbon paper and found that the electrode materials are able to store the charge through dominant intercalation redox process (battery‐type storage mechanism). Among them, Ni3Se4 (NS‐15E(1)) synthesized in water/ethanol (2 : 3) mixture with Ni/Se (1 : 1) ratio has displayed a high specific capacity of 376 C g−1 (104 mA hg−1) at a current density of 1 A g−1 in 2 m KOH. The superior charge storage of NS‐15E(1) could be attributed to the improved redox process facilitated by the easier diffusion of electrolyte ions into the bulk of the material. Furthermore, a hybrid device fabricated by using Activated charcoal (AC) and NS‐15E(1) as negative and positive electrodes, respectively has showed an extended voltage window of 1.6 V and achieved a high energy density ∼20 Wh Kg−1 at a power density of 329 W kg−1.
Potential‐Modulated Ion Distributions in the Back‐to‐Back Electrical Double Layers at a Polarised Liquid|Liquid Interface Regulate the Kinetics of Interfacial Electron Transfer
Authors: Gamero‐Quijano Alonso , Manzanares José A. , Ghazvini Seyed M. B. H. , Low Paul J. , Scanlon Micheál D. 
Published: December 2022

AbstractBiphasic interfacial electron transfer (IET) reactions at polarisable liquid|liquid (L|L) interfaces underpin new approaches to electrosynthesis, redox electrocatalysis, bioelectrochemistry and artificial photosynthesis. Herein, using cyclic and alternating current voltammetry, we demonstrate that under certain experimental conditions, the biphasic 2‐electron O2 reduction reaction can proceed by single‐step IET between a reductant in the organic phase, decamethylferrocene, and interfacial protons in the presence of O2. Using this biphasic system, we demonstrate that the applied interfacial Galvani potential difference
provides no direct driving force to realise a thermodynamically uphill biphasic IET reaction in the mixed solvent region. We show that the onset potential for a biphasic single‐step IET reaction does not correlate with the thermodynamically predicted standard Galvani IET potential and is instead closely correlated with the potential of zero charge at a polarised L|L interface. We outline that the applied
required to modulate the interfacial ion distributions, and thus kinetics of IET, must be optimised to ensure that the aqueous and organic redox species are present in substantial concentrations at the L|L interface simultaneously in order to react.
Theoretical and Experimental Investigations of Stable Arylfluorene‐Based Radical‐Type Mechanophores
Authors: Sugita Hajime , Lu Yi , Aoki Daisuke , Otsuka Hideyuki , Mikami Koichiro 
Published: December 2022

AbstractRadical‐type mechanophores (RMs) can undergo homolytic cleavage of their central C−C bonds upon exposure to mechanical forces, which affords radical species. Understanding the characteristics of these radical species allows bespoke mechanoresponsive materials to be designed and developed. The thermal stability of the central C−C bonds and the oxygen tolerance of the generated radical species are crucial characteristics that determine the functions and applicability of such RM‐containing mechanoresponsive materials. In this paper, we report the synthesis and characterization of two series of arylfluorene‐based RM derivatives, that is, 9,9’‐bis(5‐methyl‐2‐pyridyl)‐9,9’‐bifluorene (BPyF) and 9,9’‐bis(4,6‐diphenyl‐2‐triazyl)‐9,9’‐bifluorene (BTAF). BPyF and BTAF derivatives were synthesized without generating any peroxides initially, albeit that BPyF slowly converted to the corresponding peroxide in solution. DFT calculations revealed the importance of the thermodynamic stability and the values of the α‐SOMO levels of the corresponding radical species for their thermal stability and oxygen tolerance. Furthermore, the mechanochromism of BTAF was demonstrated by ball‐milling a BTAF‐centered polymer, which was synthesized by atom‐transfer radical polymerization (ATRP).
Investigating the agreement between polarized and unpolarized densitometry in offset lithography printing
Authors: Schneider Devin J. , Myers Bruce L. , Altay Bilge Nazli 
Published: December 2022

AbstractAutomated color measurement systems have become significant components of offset lithographic printing presses for better process control and reduced job waste. Some European press manufacturers are known to offer automated color measurement equipment that is confined to polarized density readings, which is uncommon in US. Introducing polarized densitometry into an environment where unpolarized densitometry is utilized can be problematic. Print professionals are on the lookout for a solution that is evidenced by a recent feature in a post from the IDEAlliance G7 Professionals forum seeking for a methodology to convert polarized to unpolarized readings. The present study applies the Bland–Altman method together with other statistical analyses to determine if a conversion between polarized and unpolarized densitometry can be established within a limited set of parameters. Three spectrodensitometers were used to record densitometric readings of wet and dry process inks on coated and uncoated drawdown proofs. The results showed that coated papers had significantly less variation between instruments compared to uncoated papers. Wet inks had more minor variations compared to dry inks. Furthermore, pure difference values and a Mann–Whitney U test indicated differences between unpolarized and polarized densitometric readings in all cases. Finally, t‐tests performed on the resulting difference data for both unpolarized versus polarized and unpolarized versus predicted polarized that showed fixed bias by means of the computed p‐values.
Pharmacokinetics, Bioequivalence, and Safety Evaluation of Two Formulations of 0.2‐g Ibuprofen Granules
Authors: Su Jianfen , Zhang Canhua , Su Yue , Huang Chen , Zhao Jinlong , Yang Hui , Xu Zuoheng , Li Jianhao , Yang Xinchun 
Published: December 2022

AbstractIbuprofen is a nonsteroidal anti‐inflammatory agent. In this study, we compared the pharmacokinetic properties, bioequivalence, and safety of a newly developed generic formulation (test) and a branded formulation (reference) of 0.2 g ibuprofen granules in healthy Chinese participants in fasting and fed arms. The randomized, single‐dose, open‐label, two‐preparation, two‐sequence, two‐period crossover study had a washout period of 7 days between each period. It was conducted in 72 participants, 24 in the fasting arm and 48 in the fed arm. The concentration of ibuprofen in the plasma was determined using high‐performance liquid chromatography‐tandem mass spectroscopy. The primary pharmacokinetic parameters were calculated using a noncompartmental model. Safety assessments were performed throughout the study. The mean values of Cmax, AUC0‐t, and AUC0‐∞ for the test and reference preparations of ibuprofen were 19 295 and 21 101 ng/mL, 70 795 and 70 558 ng * h/mL, and 72 023 and 71 647 ng * h/mL, respectively, in the fasting arm and 11 299 and 11 605 ng/mL, 70 983 and 69 157 ng * h/mL, and 73 279 and 71 267 ng * h/mL, respectively, in the fed arm. For all parameters, bioequivalence was within acceptable limits. No serious adverse reactions were reported in this study. This study demonstrated that the 2 formulations of ibuprofen granules were bioequivalent in healthy Chinese volunteers under fasting and fed conditions.
Ransomware prevention using moving target defense based approach
Authors: Khan Muhammad Mubashir , Hyder Muhammad Faraz , Khan Shariq Mahmood , Arshad Junaid , Khan Muhammad M. 
Published: December 2022

AbstractOver the past decade, there has been a rapidly rising trend of malware (ransomware) that limits user access by encrypting the data and demanding the ransom against the decryption key. In most cases, such encryption may lead to a permanent data loss. In order to prevent this unwanted encryption, we propose a method based on Moving Target Defense (MTD) approach. Our method is based on the alteration of the attack surface to reduce the attack success ratio. We have used multiple layers of MTD. The first layer generates random extensions that hide the existing known file extensions. This will protect user files against those ransomware variants which encrypt files having some specific extensions. Our second layer of protection uses event‐based MTD in which tasks are scheduled to change file extensions at the occurrence of specific events which mostly occur due to the execution of ransomware in the system. As a result of our proposed method, we have successfully protected user files against well‐known ransomware variants such as WannaCry, Cerber, Locky, Tesla, Revil, Bitlocker, Darkside, Ranzy.
Toward intelligent resource management in dynamic Fog Computing‐based Internet of Things environment with Deep Reinforcement Learning: A survey
Authors: Gupta Shally , Singh Nanhay 
Published: December 2022

SummaryFog computing has already started to gain a lot of momentum in the industry for its ability to turn scattered computing resources into a large‐scale, virtualized, and elastic computing environment. Resource management (RM) is one of the key challenges in fog computing which is also related to the success of fog computing. Deep learning has been applied to the fog computing field for some time, and it is widely used in large‐scale network RM. Reinforcement learning (RL) is a type of machine learning algorithms, and it can be used to learn and make decisions based on reward signals that are obtained from interactions with the environment. We examine current research in this area, comparing RL and deep reinforcement learning (DRL) approaches with traditional algorithmic methods such as graph theory, heuristics, and greedy for managing resources in fog computing environments (published between 2013 and 2022) illustrating how RL and DRL algorithms can be more effective than conventional techniques. Various algorithms based on DRL has been shown to be applicable to RM problem and proved that it has a lot of potential in fog computing. A new microservice model based on the DRL framework is proposed to achieve the goal of efficient fog computing RM. The positive impact of this work is that it can successfully provide a resource manager to efficiently schedule resources and maximize the overall performance.
Classical versus reinforcement learning algorithms for unmanned aerial vehicle network communication and coverage path planning: A systematic literature review
Authors: Mannan Abdul , Obaidat Mohammad S. , Mahmood Khalid , Ahmad Aftab , Ahmad Rodina 
Published: December 2022

SummaryThe unmanned aerial vehicle network communication includes all points of interest during the coverage path planning. Coverage path planning in such networks is crucial for many applications, such as surveying, monitoring, and disaster management. Since the coverage path planning belongs to NP‐hard issues, researchers in this domain are constantly looking for optimal solutions for this task. The speed, direction, altitude, environmental variations, and obstacles make coverage path planning more difficult. Researchers have proposed numerous algorithms regarding coverage path planning. In this study, we examined and discussed existing state‐of‐the‐art coverage path planning algorithms. We divided the existing techniques into two core categories: Classical and reinforcement learning. The classical algorithms are further divided into subcategories due to the availability of considerable variations in this category. For each algorithm in both types, we examined the issues of mobility, altitude, and characteristics of known and unknown environments. We also discuss the optimality of different algorithms. At the end of each section, we discuss the existing research gaps and provide future insights to overcome those gaps.
Identification ofHSPA8as an interacting partner ofMAB21L2and an important factor in eye development
Authors: Seese Sarah E. , Muheisen Sanaa , Gath Natalie , Gross Jeffrey M. , Semina Elena V. 
Published: December 2022

AbstractBackgroundPathogenic variants in humanMAB21L2result in microphthalmia, anophthalmia, and coloboma. The exact molecular function of MAB21L2 is currently unknown. We conducted a series of yeast two‐hybrid (Y2H) experiments to determine protein interactomes of normal human and zebrafish MAB21L2/mab21l2 as well as human disease‐associated variant MAB21L2‐p.(Arg51Gly) using human adult retina and zebrafish embryo libraries.ResultsThese screens identified klhl31, tnpo1, TNPO2/tnpo2, KLC2/klc2, and SPTBN1/sptbn1 as co‐factors of MAB21L2/mab21l2. Several factors, including hspa8 and hspa5, were found to interact with MAB21L2‐p.Arg51Gly but not wild‐type MAB21L2/mab21l2 in Y2H screens. Further analyses via 1‐by‐1 Y2H assays, co‐immunoprecipitation, and mass spectrometry revealed that both normal and variant MAB21L2 interact with HSPA5 and HSPA8. In situ hybridization detected co‐expression ofhspa5andhspa8withmab21l2during eye development in zebrafish. Examination of zebrafish mutanthspa8hi138Tgidentified reducedhspa8expression associated with severe ocular developmental defects, including small eye, coloboma, and anterior segment dysgenesis. To investigate the effects ofhspa8deficiency on themab21l2Arg51_Phe52delallele, corresponding zebrafish double mutants were generated and found to be more severely affected than single mutant lines.ConclusionThis study identifies heat shock proteins as interacting partners of MAB21L2/mab21l2 and suggests a role for this interaction in vertebrate eye development.