bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge Domain and Global Tendency in Publication Ethics Research: Bibliometric Review and Mapping Analysis
Authors: Zhang Mingyue , Li Yanming , Xu Caihua , Liu Ming , Xu Jianguo , Zheng Qingyong , Zhao Liang , Zhang Jun , Fu Hui , Wu Songlin , Qi Wen’an , Zhang Junhua , Tian Jinhui 
Published: April 2023

Abstract

ObjectiveThe purpose of the present study was to gain a deeper understanding of research status and future prospects in the field of publication ethics.MethodsA bibliometric analysis was performed to identify published researches about publication ethics. Searching from the Web of Science database and publication ethics guidelines website. The VOSviewer 1.6.18, CiteSpace 6.1.R3, R-bibliometric, HistCite 12.03.17 and Excel 2021 softwares were used to visually analyze information.ResultsIn total, 659 articles of publication ethics were identified, and the first indicated literature appeared in 1972. A total of 762 institutions from 67 countries participated in this field research, and the United States of America contributed the largest publication output. The most productive institution was Sideview, and Wager Elizabeth who had posted the most articles. TheSci Eng Ethics(29 articles) was the most prolific and highest citation journal. Related topics of the research on publication ethics of biomedical journals is a hot and high maturity research topic. Misconduct in scientific publishing is a hot theme and development trend in the future.ConclusionThis study summarized the publication information of publication ethics from 1972–2022, including countries, institutions, authors, journals and references. The research hot topics were pointed out, and the collaboration between countries, authors and institutions need to be further strengthened in the future. In order to improve the quality and efficiency of research output, the integration of scientific research and resources, as well as scientific collaboration are needed.
Repositioning Dislocated One-Piece IOLs by Modified Scleral Suture Fixation
Authors: Lin Binwu , Huang Weilan , Ou Yang 
Published: April 2023

Abstract
Purpose: To evaluate the efficacy and safety of intraocular lens (IOL) repositioning by modified scleral suturing of 1-piece IOLs.
Methods: ​The surgical database of 1 surgeon was reviewed for consecutive cases of IOLs dislocated into the vitreous from April 2019 to January 2022, where a modified scleral suture-fixation technique was used with a minimum follow-up of 3 months. Preoperative and postoperative ophthalmic evaluation included the best-corrected visual acuity (BCVA), intraocular pressure (IOP), and detailed slit-lamp examinations.
Results: The eyes of 11 consecutive patients with in-bag dislocated IOLs were included. The etiological distribution of the 11 study subjects was as follows: 3 eyes undergoing prior vitrectomy, 3 high-myopia eyes, 2 eyes implanted with a capsular tension ring (CTR), 1 eye with trauma and 2 eyes with unknown etiologies. The interval between the original cataract surgery and the dislocation ranged from 3 to 120 months (48.09±44.48 months). The mean follow-up time was 14.55±5.34 months. At the most recent follow-up visit, all IOLs were stable with no significant lens tilt, and the mean BCVA of all patients improved significantly from 0.49±0.26 to 0.29±0.17 (logMAR, p<0.05, t =2.204). Surgical complications in this research included elevated lOP (2 eyes) and CME (1 eye), which all could be resolved by topical use of eyedrops.
Conclusion: Repositioning 1-piece IOLs in this modified manner is a simple, effective, and safe method that may also be suitable for other types of IOLs with similar structures.
Significance of Prolific Specified Expectant Mothers’ Acceptance of New Pregnancies
Authors: Yamaguchi Natsuki , Nakagomi Satoko 
Published: April 2023

Abstract
Background The study aims to describe the experience of grand multiparas in Japan who have been identified as specified expectant mothers to accept unexpected new pregnancies and decide to give birth and raise their newborns. The results of this study show potential implications for improvements in childbirth as a happy experience, safe and inclusive abortion care, a support for resolving health issues from financial difficulties to promote a financially stable life, or improvements in the quality of sexual and reproductive health and rights in Japan.Methods Specified expectant mothers visiting X hospital underwent a series of semi-structured interviews during their pregnancy. The interview entailed the living conditions of expectant mothers, the circumstances of their current pregnancy and the process of its acceptance, and their decisions or feelings regarding giving birth and raising their newborns. A phenomenological approach was employed as the analysis method.Results Participants included seven grand multiparas in their early 30s to early 40s, all of whom were expecting at least their fourth child. Three lived with their partners, and four were separated. Regarding their financial status, two of them received welfare support, and five of them were either employed or suspended/retired temporarily from their jobs. Three themes were identified as follows in the results of this study investigating the responses on unexpected pregnancies of grand multiparas identified as specified expectant mothers; 1) actual pregnancy under unintended circumstances with possibilities of pregnancy; 2) encouragement for delivery; and 3) live in relationship with someone irreplaceable.Conclusions The seven grand multiparas identified as specified expectant mothers had certain issues, including unmarried pregnancy, receiving public assistance, and financial difficulties from non-regular employment while raising three or more children. Despite these, they decided to give birth and raise the newly conceived newborns owing to the positive welcome from their partners or other children who appreciated their motherhood.
Three-dimensional electrical impedance tomography (EIT) to study regional ventilation/perfusion (V/Q̇ ) ratios in anesthetized pigs
Authors: Larrabee Shannon , Nugen Sarah , Bruhn Alejandro , Stowe Symon , Adler Andy , Martin-Flores Manuel , Araos Joaquin 
Published: April 2023

Abstract
This study aimed to develop a 3D method for assessing V/Q̇ ratios in a pig model of hemodynamic perturbations using electrical impedance tomography (EIT). In order to evaluate whether the physiological coherence of changes in EIT-derived V/Q̇ ratios, global EIT-derived V/Q̇ mismatch were compared with global gold-standards. The study found regional heterogeneity in the distribution of V/Q̇ ratios in both the ventrodorsal and craniocaudal directions. Although global EIT-derived indices of V/Q̇ mismatch consistently underestimated both low and high V/Q̇ mismatch compared to global gold standards, the direction of the change was similar. We have made the software available at no cost for other researchers to use. Future studies should compare regional V/Q̇ ratios determined by our method against other regional, high-resolution methods such as SPECT or PET scan.
Tele-robotic distal gastrectomy with lymph node dissection on a cadaver
Authors: Ebihara Yuma , Hirano Satoshi , Kurashima Yo , Takano Hironobu , Murakami Soichi , Shichinohe Toshiaki , Morohashi Hajime , Oki Eiji , Hakamada Kenichi , Ikeda Norihiko , Mori Masaki 
Published: April 2023

Abstract
Purpose Robotic telesurgery is growing in popularity; however, it has not yet been validated for gastrointestinal cancer surgery. The purpose of this study is to evaluate the performance of tele-robotic distal gastrectomy (tele-RDG) with lymph node dissection (LND) using a novel Japanese-made surgical robot hinotori™ (Medicaroid, Kobe, Japan) in a cadaver with a presumptive gastric cancer.Methods The Cadaveric Anatomy and Surgical Training laboratory (CAST-Lab.) at Hokkaido University and Kushiro City General Hospital (KCGH) are connected by a guaranteed type line (1 Gbps), and the distance between the two facilities is 250 km. The communication system was conducted over a commercial general line and used hinotori™. A patient cart was installed at CAST-Lab, and a surgeon cockpit was installed at KCGH. Tele-RDG with D2 LND was performed on an adult human cadavers. The evaluation methods included round-trip time (RTT), operation time, Robot Usability Score (RUS), system usability scale (SUS), Global Evaluative Assessment of Robotic Skills (GEARS), and System and Piper Fatigue Scale-12 (PFS-12).Results In all surgical processes, the communication environment was stable without image degradation, and the mean RTT was 40 ms (36.5–55 ms). For tele-RDG with D2 LND, the operation time was 199 min. without any organ injury or technical problems, and the technical evaluation scores (GEARS:28, GOALS:23), usability scores (RUS:34, SUS:82.5), and surgeon fatigue scores (PFS-12:26) were acceptable.Conclusion Tele-RDG with LND using hinotori ™ was feasible and similar to local robotic RDG.
Arthroscopic scapholunate ligament repair and dorsal capsulodesis with suture anchor in acute scapholunate dissociation
Authors: Lee YuCheng , Shih Juitien 
Published: April 2023

Abstract
Purpose
The objective of this study was to investigate the potential of arthroscopic scapholunate repair and dorsal capsulodesis with suture anchor as a treatment option for patients experiencing symptomatic acute scapholunate instability in the absence of wrist advanced degenerative changes.
Methods
From Jan. 2017 to Jan 2020, 19 wrists with acute tears of the SL ligament with symptomatic instability, were treated with arthroscopic SL repair and dorsal capsulodesis with suture anchor and scapholunate joint fixation with K-wires. All patients underwent wrist MRI and arthroscopy to confirm the diagnosis and exclude arthritis. The study included 16 men and 3 women with an average age of 24.5 years (range, 19 to 27 years). The average time from injury to operation was 8.8 weeks (range, 4 to 11 weeks). All patients underwent follow-up at our clinic regularly for an average of 26.5 months (range, 24 to 32 months).
Results
All 19 patients had rupture and dissociation of the SL ligament in the radiocarpal joint. Modified Mayo wrist scores revealed the following functionality: the total arc of wrist motion in the flexion-extension plane loss averaged 5.1° (P > .01). Grip force improved significantly, with 14.7% improvement of that on the normal side (P < .01). The Wilcoxon signed-rank test was used to compare the results: the postoperative scores were significantly better than the preoperative scores (P < .01). Sixteen patients (84.2%) were fully satisfied with the results and returned to their preinjury activity. Only one patient (5.3%) had mild laxity of the scapholunate ligament joint.
Conclusions
At a minimum of two years' follow-up, patients with acute symptomatic dissociation of scapholunate ligament instability who underwent arthroscopic scapholunate ligament repair and dorsal capsulodesis with suture anchor treatment had satisfactory results.
Level of Evidence
Level IV, case series.
Complementing or competing with public transit? Evaluating the parameter sensitivity of potential Mobility-as-a-Service (MaaS)urban users in Germany, the Czech Republic,Poland, and the United Kingdom with a mixed choice model
Authors: Matowicki Michal , Pecherkova Pavla , Amorim Marco , Kern Mira , Nagy Ivan , Motzer Nicolaj , Pribyl Ondrej 
Published: April 2023

Abstract

In this study we conduct a large survey (n=6,405) on urban daily commuters in four European countries (Germany, the United Kingdom, Poland, and the Czech Republic), we add richness to our understanding of who will use Mobility-as-a-Service (MaaS) options and what relationship MaaS has with public transit in terms of choosing how to travel. We explored how sensitive participants were to changes in pricing and travel times, and also examined how likely different kinds of participants, grouped into segments (user groups) with similar characterizes, were to public transportation, MaaS, or private cars. We concluded that the basic mobility factors such as price and travel time can increase the likelihood of using a certain option, as we notably observed in the “Unspecified Users” group. Our complex approach, combining several mathematical modelling tools, provided insight into the choices people make into choosing among different travel options, and our findings may be leveraged by decision makers to create better, more informed approaches towards promoting sustainable alternatives to car use in urban settings.
Amlodipine besylate solubility in polyethylene glycol 400 + ethanol at different temperatures: Thermodynamic analysis and data modeling
Authors: Sayad Taher , Moradi Milad , Jafari Parisa , Rahimpour Elaheh , Jouyban Abolghasem 
Published: April 2023

Abstract
In the present study, the solubility values of amlodipine besylate (AMB) in the binary mixtures of polyethylene glycol 400 and ethanol were determined using the shake-flask method at 293.2 to 313.2 K under atmospheric pressure (≈ 85 kPa) and correlated to some cosolvency and activity coefficient models. The accuracy of each model was marked by the mean relative deviations (MRD%) of the back-calculated solubility data. Also, the apparent thermodynamic properties of AMB dissolution were computed by the van't Hoff and Gibbs equations.
Clinicopathological features and prognosis of colorectal cancer patients with chronic schistosomiasis
Authors: Ge Heming , Liu Xionglin , Zheng Linyi , Tao Zui , Li Yuqiang , Pei Haiping 
Published: April 2023

Abstract
Background: Schistosomiasis, as the second largest parasitic disease in the world, has infected more than 200 million people. Previous studies have found a correlation between schistosomiasis and the occurrence and development of colorectal cancer. However, there is still a lack of large-scale studies reporting whether schistosomiasis affects the prognosis of colorectal cancer and the treatment standards for schistosomiasis-associated colorectal cancer. This study aims to investigate the clinicopathological characteristics and prognosis of colorectal cancer patients with chronic schistosomiasis (CRCS+).Methods: We collected data from 94 CRCS+ patients diagnosed at Xiangya Hospital of Central South University between January 1, 2014 and December 31, 2019. Using propensity score matching, we selected 94 colorectal cancer patients without chronic schistosomiasis (CRCS−) and retrospectively analyzed the clinical and pathological data of both groups.Results: Compared to CRCS− patients, CRCS+ patients exhibited distinct clinicopathological features such as regional clustering, advanced age, severe liver function impairment, and a lower positive rate of fecal monoclonal blood tests. Calcification was a characteristic feature of CRCS+ patients. Overall survival was worse for colorectal cancer patients with chronic schistosomiasis.Conclusions: Schistosomiasis may be considered an independent risk factor for colorectal cancer.
Insights into the genetic influences of the microbiota on the life span of a host
Authors: Zhang Fang , Wang Liying , Jin Jiayu , Pang Yulu , Shi Hao , Fang Ziyi , Du Yujie , Hu Yufan , Zhang Yingchun , Ding Xiaoyue , Zhu Zuobin , Wang Han 
Published: April 2023

Abstract
Escherichia coli (E. coli) mutant strains have been reported to extend the life span of Caenorhabditis elegans (C. elegans). However, the specific mechanisms through which the genes and pathways affect aging are not yet clear. In this study, we fed Drosophila melanogaster (fruit fly) various E. coli single-gene knockout strains to screen mutant strains with an extended lifespan. The results showed that D. melanogaster fed with E. coli purE had the longest average lifespan, which was verified by C. elegans. We conducted a whole-genome sequencing and analysis of C. elegans fed with E. coli purE (a single-gene knockout mutant) to further explore the underlying molecular mechanism. We used the differential gene analysis (DGA), enrichment analysis, and gene set enrichment analysis (GSEA) to screen vital pathways and modules with significant changes in overall expression and two differential genes (cfz-2 and catp-4) associated with known longevity pathways. Our results suggest that E. coli mutant strains may affect the host lifespan by regulating the protein synthesis rate (cfz-2) and ATP level (catp-4). To conclude, our study could provide new insights into the genetic influences of the microbiota on the life span of a host and a basis for developing anti-aging probiotics and drugs.
Stage and location related intratumoral microbiota are associated with patient prognosis and immune infiltration in colorectal cancer
Authors: Zhao Mengyu , Zhang Xiang , Wang Fuhao , Hu Xiaoyu , Xue Zhuang , Chen Ming , Yue Jinbo 
Published: April 2023

Abstract

Purpose:The colorectal intratumoral microbiome and its association with immune infiltration remain poorly characterized. Our study aims to investigate the relationship between intratumoral microbiota with immune infiltration, patient prognosis, and potential signal pathways.Methods:We collected biopsy samples of tumor and paracancerous tissue from 92 patients with colorectal cancer (CRC), and acquired microbiota profiling using 16S rRNA sequencing. Meanwhile, the immune markers including CD8, FOXP3, CD163, PD-1 and PD-L1 were stained by immunohistochemistry (IHC) to identify the immune infiltration in tumors. Furthermore, we used The Cancer Genome Atlas databases to conduct analysis on intratumoral flora and patient survival, tumor gene expression profile and potential downstream pathways.Results:We discovered that the β-diversity of bacterial composition differed considerably by CRC stage (earlyvs.advanced stage,P= 0.049) and location (leftvs.right colon,P= 0.04). Stage-related flora cluster (Porphyromonas, Lachnoclostridium, Bacteroides, Aggregatibacter,andHungatella) were associated with poor prognosis in CRC patients (HR=1.79,P=0.015). By IHC staining, we found that expression of PD-1 and FOXP3 was significantly reduced at low abundance of stage-related bacterial cluster (P<0.05). Besides, tumor-location related flora cluster (BacteroidesandBlautia) were associated with good prognosis in CRC patients (HR=0.52,P=0.011). Expression of CD163 was decreased at high abundance of location-related bacterial cluster (P<0.05). Furthermore, we identified probable pathways connected to three distinct genera (Blautia,Hungatella, andBacteroides).Conclusion:Our study elucidates the relationships among intratumoral microbiota, immune infiltration, patient prognosis, and potential signal pathways, thereby providing new data for future intratumoral microbiota research.
A new perspective into the discovery of diversity of sea cucumbers (Echinodermata: Holothuroidea)
Authors: Martins Luciana , Costa Karen , Toledo Felipe 
Published: April 2023

Abstract
The study of disarticulated ossicles of recent sea cucumbers from Campos Basin, Rio de Janeiro, Brazil, from various Holocene strata, obtained by micropaleontological methods, resulted in the identification of at least eight holothurian taxa, belonging to the four of the seven orders of Holothuroidea: Apodida (Synaptidae, Chiridotidae), Dendrochirotida (Psolidae and Cucumariidae), Holothuriida (Holothuria) and Molpadiida (Molpadiidae, Eupyrgidae). Our paper endorses the importance of studies of recent fauna based on isolated ossicles for taxonomy, biostratigraphy, and ecology. This study represents the first effort at the study of recent fauna of sea cucumbers based on the analysis of preserved ossicles in marine sediments.
Investigation of water environment monitoring and evaluation based on water ecological function zoning
Authors: Liu Yuyong 
Published: April 2023

AbstractThis paper expounds the establishment of the water environment evaluation system and the water environment monitoring (EM) countermeasures and discusses the water environment security evaluation index system. The establishment of a water environment-sensitive monitoring area was proposed, and the establishment of a water EM network system was studied. The construction of water EM and evaluation based on the entropy weight method was carried out, and the analysis of water EM and evaluation elements of ecological function zoning were proposed. The research was carried out from two aspects, namely the problems solved by water EM and evaluation based on water ecological function zoning, and the water environment evaluation system based on water ecological function zoning. According to the experiment and investigation, the entropy weight method was introduced into the framework of the water EM and evaluation system, and a new water EM and evaluation system was constructed, which was 19% more satisfactory than the traditional water EM and evaluation system.
Phthalate esters: occurrence, toxicity, bioremediation, and advanced oxidation processes
Authors: Kumari Madhu , Pulimi Mrudula 
Published: April 2023

Abstract

Phthalic acid esters are emerging pollutants, commonly used as plasticizers that are categorized as hazardous endocrine-disrupting chemicals (EDCs). A rise in anthropogenic activities leads to an increase in phthalate concentration in the environment which leads to various adverse environmental effects and health issues in humans and other aquatic organisms. This paper gives an overview of the research related to phthalate ester contamination and degradation methods by conducting a bibliometric analysis with VOS Viewer. Ecotoxicity analysis requires an understanding of the current status of phthalate pollution, health impacts, exposure routes, and their sources. This review covers five toxic phthalates, occurrences in the aquatic environment, toxicity studies, biodegradation studies, and degradation pathways. It highlights the various advanced oxidation processes like photocatalysis, Fenton processes, ozonation, sonolysis, and modified AOPs used for phthalate removal from the environment.