bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant and hypoglycemic potential of phytogenic cerium oxide nanoparticles
Authors: Khan Maarij , Sohail  , Raja Naveed Iqbal , Asad Muhammad Javaid , Mashwani Zia-ur-Rehman 
Published: March 2023

AbstractPlants provide humans with more than just food and shelter; they are also a major source of medications. The purpose of this research was to investigate the antioxidant and hypoglycemic potential of green synthesized CeONPs usingMentha royleanaleaves extract. The morphological and physicochemical features of CeONPs were evaluated by UV–Visible spectrophotometry, Scanning Electron Microscopy, Energy Dispersive X-rays and Fourier-transform infrared spectrometry, Dynamic light scattering, Atomic Force Microscopy, Zeta Potential. The average size range of synthesized CeONPs diameter between 46 and 56 nm, crystalline in shape, with Polydispersity index value of 0.2 and subatomic particles mean diameter was 4.5–9.1 nm. The antioxidant capability of CeONPs was assessed using DPPH, ABTS+, hydrogen peroxide, hydroxyl radical scavenging, and reducing power tests. The hypoglycemic potential of CeONPs was investigated using alpha-amylase, alpha-glucosidase, glucose absorption by yeast cells, and antisucrase. The effective concentrations were 500 and 1000 µg/ml found good in suppressing radical species. To explore the hypoglycemic potential of CeONPs, alpha-amylase, alpha-glucosidase, glucose absorption by yeast cell, and antisucrase assays were performed. Glucose absorb by yeast cells assay was tested for three distinct glucose concentrations: 5 mmol/L, 10 mmol/L, and 25 mmol/L. Green synthesize CeONPs showed a dose-dependent response, higher concentrations of CeONPs imposed a stronger inhibitory impact on the catalytic site of enzymes. This study suggest that CeONPs could possibly binds to the charge carrying species and act as competitive inhibitor which slow down the enzyme substrate reaction and prevents enzymatic degradation. The study’s findings were outstanding, which bodes well for future medicinal applications of CeONPs.
Nonreciprocal forces enable cold-to-hot heat transfer between nanoparticles
Authors: Loos Sarah A. M. , Arabha Saeed , Rajabpour Ali , Hassanali Ali , Roldán Édgar 
Published: March 2023

AbstractWe study the heat transfer between two nanoparticles held at different temperatures that interact through nonreciprocal forces, by combining molecular dynamics simulations with stochastic thermodynamics. Our simulations reveal that it is possible to construct nano refrigerators that generate a net heat transfer from a cold to a hot reservoir at the expense of power exerted by the nonreciprocal forces. Applying concepts from stochastic thermodynamics to a minimal underdamped Langevin model, we derive exact analytical expressions predictions for the fluctuations of work, heat, and efficiency, which reproduce thermodynamic quantities extracted from the molecular dynamics simulations. The theory only involves a single unknown parameter, namely an effective friction coefficient, which we estimate fitting the results of the molecular dynamics simulation to our theoretical predictions. Using this framework, we also establish design principles which identify the minimal amount of entropy production that is needed to achieve a certain amount of uncertainty in the power fluctuations of our nano refrigerator. Taken together, our results shed light on how the direction and fluctuations of heat flows in natural and artificial nano machines can be accurately quantified and controlled by using nonreciprocal forces.
Assessing compatibility and viral fitness between poultry-adapted H9N2 and wild bird-derived neuraminidases
Authors: Wasberg Anishia , Faria Inês R. , Bergholm Julia , Petric Philipp P. , Mostafa Ahmed , Pleschka Stephan , Schwemmle Martin , Lundkvist Åke , Ellström Patrik , Naguib Mahmoud M. 
Published: March 2023

AbstractExchange of viral segments between one or more influenza virus subtypes can contribute to a shift in virulence and adaptation to new hosts. Among several influenza subtypes, H9N2 is widely circulating in poultry populations worldwide and has the ability to infect humans. Here, we studied the reassortant compatibility between chicken H9N2 with N1–N9 gene segments of wild bird origin, either with an intact or truncated stalk. Naturally occurring amino acid deletions in the NA stalk of the influenza virus can lead to increased virulence in both mallard ducks and chickens. Our findings show extended genetic compatibility between chicken H9Nx gene segments and the wild-bird NA with and without 20 amino acid stalk deletion. Replication kinetics in avian, mammalian and human cell lines revealed that parental chH9N2 and rH9N6 viruses with intact NA-stalk replicated significantly better in avian DF1 cells compared to human A549 cells. After introducing a stalk deletion, an enhanced preference for replication in mammalian and human cell lines could be observed for rH9N2Δ(H6), rH9N6Δ and rH9N9Δ compared to the parental chH9N2 virus. This highlights the potential emergence of novel viruses with variable phenotypic traits, warranting the continuous monitoring of H9N2 and co-circulating subtypes in avian hosts.
Durable superhydrophobic/superoleophilic melamine foam based on biomass-derived porous carbon and multi-walled carbon nanotube for oil/water separation
Authors: Shayesteh Hadi , Khosrowshahi Mobin Safarzadeh , Mashhadimoslem Hossein , Maleki Farid , Rabbani Yahya , Emrooz Hosein Banna Motejadded 
Published: March 2023

AbstractIn the present study, fabrications of two eco-friendly superhydrophobic/superoleophilic recyclable foamy-based adsorbents for oil/water mixture separation were developed. Hierarchically biomass (celery)-derived porous carbon (PC) and multi-walled carbon nanotube (MWCNT) were firstly synthesized and loaded on pristine melamine foam (MF) by the simple dip-coating approach by combining silicone adhesive to create superhydrophobic/superoleophilic, recyclable, and reusable three-dimensional porous structure. The prepared samples have a large specific surface area of 240 m2/g (MWCNT), 1126 m2/g (PC), and good micro-mesoporous frameworks. The water contact angle (WCA) values of the as-prepared foams, PC/MF and MWCNT/MF, not only were 159.34° ± 1.9° and 156.42° ± 1.6°, respectively but also had oil contact angle (OCA) of equal to 0° for a wide range of oils and organic solvents. Therefore, PC/MF and MWCNT/MF exhibited superhydrophobicity and superoleophilicity properties, which can be considered effective adsorbents in oil/water mixture separations. In this context, superhydrophobic/superoleophilic prepared foams for kind of different oils and organic solvents were shown to have superior separation performance ranges of 54–143 g/g and 46–137 g/g for PC/MF and MWCNT/MF, respectively, suggesting a new effective porous material for separating oil spills. Also, outstanding recyclability and reusability of these structures in the ten adsorption-squeezing cycles indicated that the WCA and sorption capacity has not appreciably changed after soaking into acidic (pH = 2) and alkaline (pH = 12) as well as saline (3.5% NaCl) solutions. More importantly, the reusability and chemical durability of the superhydrophobic samples made them good opportunities for use in different harsh conditions for oil-spill cleanup.
Effect of heat treatment atmospheres on microstructure evolution and corrosion resistance of 2205 duplex stainless steel weldments
Authors: Mohamed Abdelkarim Yousif , Mohamed Ahmed Hussein Abdelraheem , Abdel Hamid Z. , Farahat Ahmed Ismail Zaky , El-Nikhaily A. E. 
Published: March 2023

AbstractThe effects of post heat treatment atmosphere on microstructure and corrosion resistance of duplex stainless steel welded joints were investigated. Post weld heat treatment (PWHT) was carried out with and without protective atmospheres. Nitrogen and argon are used as protective gases individually. Detailed microstructure examination (optical and SEM) demonstrates that nitrides precipitates are highly observed in the welded zones for nitrogen protected samples. An observed drop of ferrite volume fraction in post weld heat treated samples compared with welded samples without heat treatment leading to corrosion resistance enhancement of heat treated welded joints. An exception for using nitrogen as heat treatment atmosphere a decreased corrosion resistance of weldments is investigated due to nitride precipitates. An increase in the weld zone hardness for post weld heat treated samples compared with base alloy. The initial hardness of duplex stainless steel was 286 Hv while average hardness of weld zone was 340, 411, 343, and 391 Hv for as welded, PWHT using air, argon, and nitrogen atmospheres, respectively. Weld zone hardness increased to 33, 44, 20, and 37%. A significant decrease in the ultimate tensile strength and elongation after PWHT. The initial Ultimate tensile strength duplex stainless steel base material was 734.9 MPa while Ultimate tensile strength of the welded joints was 769.3, 628.4, 737.8, and 681.4 MPa for the following conditions: as welded, PWHT using air, argon, and nitrogen atmospheres, respectively.
Married women with children experience greater intrasexual competition than their male counterparts
Authors: Benenson Joyce F. , Markovits Henry 
Published: March 2023

AbstractHuman males are considered to be more competitive than females. However, females must also compete for resources necessary for their own and their offsprings’ survival. Since females use more indirect forms of competition than males, comparing observable forms of competition may be misleading. One critical driver of competition is resource asymmetry. Since competition occurs primarily within sex, reactions to resource asymmetry with same-sex peers should provide an important measure of competitiveness. We asked 596 married participants, 25–45 years of age with at least one child from three different countries to evaluate how same-sex individuals they know would react to a target individual who had a valuable resource that the same-sex individuals did not have. Half the participants evaluated reactions to same-sex targets, while the other half evaluated reactions to other-sex targets. Participants reported that women would react more negatively than men to resource asymmetry with same-sex targets, but not other-sex targets. These results suggest that women may be even more competitive than men in contexts when important resources related to reproductive success are at stake.
CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain
Authors: Rege Sanket V. , Teichert Arnaud , Masumi Juliet , Dhande Onkar S. , Harish Reema , Higgins Brett W. , Lopez Yesenia , Akrapongpisak Lily , Hackbart Hannah , Caryotakis Sofia , Leone Dino P. , Szoke Balazs , Hannestad Jonas , Nikolich Karoly , Braithwaite Steven P. , Minami S. Sakura 
Published: March 2023

AbstractTargeting immune-mediated, age-related, biology has the potential to be a transformative therapeutic strategy. However, the redundant nature of the multiple cytokines that change with aging requires identification of a master downstream regulator to successfully exert therapeutic efficacy. Here, we discovered CCR3 as a prime candidate, and inhibition of CCR3 has pro-cognitive benefits in mice, but these benefits are not driven by an obvious direct action on central nervous system (CNS)-resident cells. Instead, CCR3-expressing T cells in the periphery that are modulated in aging inhibit infiltration of these T cells across the blood-brain barrier and reduce neuroinflammation. The axis of CCR3-expressing T cells influencing crosstalk from periphery to brain provides a therapeutically tractable link. These findings indicate the broad therapeutic potential of CCR3 inhibition in a spectrum of neuroinflammatory diseases of aging.
Synthesis, fabrication and characterization of 2-naphthyloxy group-substituted bis(2-pyridylimino)isoindoline and its derivatives as a positive electrode for vanadium redox flow battery applications
Authors: Gümrükçü Selin , Özçeşmeci Mukaddes , Koçyiğit Nilüfer , Kaya Kerem , Gül Ahmet , Şahin Yücel , Özçeşmeci İbrahim 
Published: March 2023

The ease of synthesis, readily modifiable structure and high stability of 1,3-bis(2-pyridylimino)isoindole (BPIs) compounds make pincer ligands suitable candidates for many potential applications.
Multi‐objective optimal planning of a residential energy hub based on multi‐objective particle swarm optimization algorithm
Authors: Davoudi Mehdi , Barmayoon Mohammad Hossein , Moeini‐Aghtaie Moein 
Published: March 2023

AbstractWith the increasing rate of population in big cities around the world, the tendency to build new buildings in the suburb of main cities or to build large apartments in the main cities has been highlighted. In this regard, building residential complexes has seen a dramatic increase in these areas as it makes it possible to build a large number of residential units within a reasonable space. Although these complexes have brought numerous benefits, they are some challenges regarding their construction processes. One main concern associated with these complexes is how to optimally install energy components such as transformers, combined heat and power (CHP) units, boilers etc., in the shared area of apartments in the residential complex. To address this issue, this paper models the energy system of a residential complex as an energy hub and proposes a novel framework to obtain the optimal planning of such an energy hub. In order to address the conflicting desires of the residential complex's builders and the future residents of the residential units, a multi‐objective (MO) optimization problem has been considered in the proposed method that simultaneously optimizes the investment costs, operation costs, and the reliability of energy supply. In this regard, a Multi‐objective Particle Swarm Optimization (MOPSO) algorithm combined with classical linear programming (LP) optimization method has been proposed to solve the MO optimization problem. In order to demonstrate the effectiveness of the proposed method, a case study including a residential complex with 300 residential units is considered, and the proposed method is implemented in this case study. The numerical results show that the proposed framework can appropriately optimize investment costs, operation costs, and the reliability index simultaneously, and the obtained Pareto frontier gives the investors the freedom to opt for any point from this surface.
TOI-1442 b and TOI-2445 b: Two potentially rocky ultra-short period planets around M dwarfs
Authors: Morello G. , Parviainen H. , Murgas F. , Pallé E. , Oshagh M. , Fukui A. , Hirano T. , Ishikawa H. T. , Mori M. , Narita N. , Collins K. A. , Barkaoui K. , Lewin P. , Cadieux C. , de Leon J. P. , Soubkiou A. , Abreu Garcia N. , Crouzet N. , Esparza-Borges E. , Fernández Rodríguez G. E. , Galán D. , Hori Y. , Ikoma M. , Isogai K. , Kagetani T. , Kawauchi K. , Kimura T. , Kodama T. , Korth J. , Kotani T. , Krishnamurthy V. , Kurita S. , Laza-Ramos A. , Livingston J. H. , Luque R. , Madrigal-Aguado A. , Nishiumi T. , Orell-Miquel J. , Puig-Subirà M. , Sánchez-Benavente M. , Stangret M. , Tamura M. , Terada Y. , Watanabe N. , Zou Y. , Benkhaldoun Z. , Collins K. I. , Doyon R. , Garcia L. , Ghachoui M. , Gillon M. , Jehin E. , Pozuelos F. J. , Schwarz R. P. , Timmermans M. 
Published: March 2023

Context. Exoplanets with orbital periods of less than one day are known as ultra-short period (USP) planets. They are relatively rare products of planetary formation and evolution processes, but especially favourable for characterisation with current planet detection methods. At the time of writing, 125 USP planets have already been confirmed.
Aims. Our aim is to validate the planetary nature of two new transiting planet candidates around M dwarfs announced by the NASA Transiting Exoplanet Survey Satellite (TESS), registered as TESS Objects of Interest (TOIs) TOI-1442.01 and TOI-2445.01.
Methods. We used TESS data, ground-based photometric light curves, and Subaru/IRD spectrograph radial velocity (RV) measurements to validate both planetary candidates and to establish their physical properties.
Results. TOI-1442 bis a validated exoplanet with an orbital period of P = 0.4090682 ± 0.0000004 day, a radius of Rp = 1.15 ± 0.06 R⊕, and equilibrium temperature of Tp,eq = 1357−42+49 K. TOI-2445 b is also validated with an orbital period of P = 0.3711286 ± 0.0000004 day, a radius of Rp = 1.33 ± 0.09 R⊕, and equilibrium temperature of Tp,eq = 1330−56+61 K. Their physical properties align with current empirical trends and formation theories of USP planets. Based on the RV measurements, we set 3σ upper mass limits of 8 M⊕ and 20 M⊕, thus confirming the non-stellar, sub-Jovian nature of both transiting objects. More RV measurements will be needed to constrain the planetary masses and mean densities, and the predicted presence of outer planetary companions. These targets extend the small sample of USP planets orbiting around M dwarfs up to 21 members. They are also among the 20 most suitable terrestrial planets for atmospheric characterisation via secondary eclipse with the James Webb Space Telescope, according to a widespread emission spectroscopy metric.
MPI-AMRVAC 3.0: Updates to an open-source simulation framework
Authors: Keppens R. , Popescu Braileanu B. , Zhou Y. , Ruan W. , Xia C. , Guo Y. , Claes N. , Bacchini F. 
Published: March 2023

Context.Computational astrophysics nowadays routinely combines grid-adaptive capabilities with modern shock-capturing, high resolution spatio-temporal integration schemes in challenging multidimensional hydrodynamic and magnetohydrodynamic (MHD) simulations. A large, and still growing, body of community software exists, and we provide an update on recent developments within the open-sourceMPI-AMRVACcode.Aims.Complete with online documentation, theMPI-AMRVAC 3.0release includes several recently added equation sets and offers many options to explore and quantify the influence of implementation details. While showcasing this flexibility on a variety of hydro-dynamic and MHD tests, we document new modules of direct interest for state-of-the-art solar applications.Methods.Test cases address how higher-order reconstruction strategies impact long-term simulations of shear layers, with and without gas-dust coupling effects, how runaway radiative losses can transit to intricate multi-temperature, multiphase dynamics, and how different flavors of spatio-temporal schemes and/or magnetic monopole control produce overall consistent MHD results in combination with adaptive meshes. We demonstrate the use of super-time-stepping strategies for specific parabolic terms and give details on all the implemented implicit-explicit integrators. A new magneto-frictional module can be used to compute force-free magnetic field configurations or for data-driven time-dependent evolutions, while the regularized-Biot-Savart-law approach can insert flux ropes in 3D domains. Synthetic observations of 3D MHD simulations can now be rendered on the fly, or in post-processing, in many spectral wavebands.Results.A particle module as well as a generic field line tracing module, fully compatible with the hierarchical meshes, can be used to do anything from sampling information at prescribed locations, to following the dynamics of charged particles and realizing fully two-way coupled simulations between MHD setups and field-aligned nonthermal processes. We provide reproducible, fully demonstrated tests of all code functionalities.Conclusions.While highlighting the latest additions and various technical aspects (e.g., reading in datacubes for initial or boundary conditions), our open-source strategy welcomes any further code usage, contribution, or spin-off development.
Handheld Ultrasound (HHUS): Potential for Home Palliative
Care
Authors: Lo Hendra , Eder Nicole , Boten David , Jenssen Christian , Nuernberg Dieter 
Published: March 2023

AbstractDue to the severity of their disease, palliative care patients often present
complex clinical symptoms and complaints like pain, shortness of breath, nausea,
loss of appetite, and fatigue. Solely relying on the information available from
the history and physical examination often causes uncertainty among palliative
care physicians regarding treatment decisions during home visits, potentially
leading to unnecessary hospitalizations or transfer to cross-sectional imaging
in radiological practices. A rational approach is essential to avoid diagnostic
aggressiveness while still providing the imaging information required for
optimal palliative care. Bedside use of handheld ultrasound (HHUS) has the
potential to expand the diagnostic and therapeutic spectrum in the case of
symptom exacerbation but is still underutilized. In this review, we evaluate the
potential uses of HHUS in home care settings to provide a more accurate
diagnosis of the most common symptoms in palliative patients and to guide
bedside interventions such as bladder catheterization, thoracentesis,
paracentesis, venous access, and regional anesthesia. Specific training programs
for ultrasound in palliative care are currently not available. Adequate
documentation is warranted but fraught with technological and privacy issues.
Expert supervision and quality assurance are necessary. Despite its limitation
and challenges, we suggest that HHUS leads to improved clinical decision-making,
expedited symptom relief, and reduced complications without burdening of the
patient and costly transfer to hospital or specialty consultations.
Regular Voluntary Running is Associated with Increased Tumor
Vascularization and Immune Cell Infiltration and Decreased Tumor Growth in
Mice
Authors: Esteves Mário , Silva Carina , Bovolini António , Pereira Sofia S. , Morais Tiago , Moreira Ângela , Costa Madalena M. , Monteiro Mariana P , Duarte Jose Alberto 
Published: March 2023

AbstractTumors present dysfunctional vasculature that limits blood perfusion and hinders
immune cells delivery. We aimed to investigate if regular voluntary running
promotes tumor vascular remodelling, improves intratumoral immune cells
infiltration and inhibits tumor growth. Tumors were induced in C57BL/6
male mice (n=28) by subcutaneous inoculation in the dorsal region with a
suspension of RM1 cells (1.5×105
cells/500 µL PBS) and randomly allocated into two
groups: sedentary (n=14) and voluntarily exercised on a wheel
(n=14). Seven mice from each group were sacrificed 14 and 28 days after
cells’ inoculation to evaluate tumor weight, microvessel density,
vessels’ lumen regularity and the intratumoral quantity of NKG2D
receptors, CD4+and CD8+T cells, by
immunohistochemistry. The statistical inference was done through a two-way
ANOVA. Exercised mice developed smaller tumors at 14 (0.17±0.1 g
vs. 0.48±0.2 g, p<0.05) and 28
(0.92±0.7 g vs. 2.09±1.3 g, p<0.05)
days, with higher microvessel density (21.20±3.2 vs. 15.86±4.0
vessels/field, p<0.05), more regular vessels’ lumen
(1.06±0.2 vs. 1.43±0.2, p<0.05), and higher
CD8+T cells (464.95±48.0 vs. 364.70±49.4
cells/mm2, p<0.01), after 28 days. NKG2D
expression was higher in exercised mice at 14 (263.27±25.8
cells/mm2, p<0.05) and 28 (295.06±56.2
cells/mm2, p<0.001) days. Regular voluntary
running modulates tumor vasculature, increases immune cells infiltration and
attenuates tumor growth, in mice.