bluuebunny/crossref_metadata_2025_split huggingface dataset:
ALHAMAT: analysing materiality of the Alhambra to elucidate the Nasrid dynasty's power in the Emirate of Granada
Authors: Cardell Carolina , García-Contreras Guillermo , Koffler Teresa , Ríos-Jiménez Juan Manuel , García-Porras Alberto , Alejandre-Sánchez Javier , Sánchez-Mesa Domingo , De La Torre-Espinosa Mario , Mattei Luca , Rodríguez-Sánchez David , Cano-Padilla Emilio , Losilla Nicolás , Cardell Esther , Nieto José Miguel , Martínez-Avila Fernando 
Published: January 2025

Abstract
The Nasrid emirate of southern Iberia emanated power through architecture; this project aims to better understand how this was made possible, via an interdisciplinary exploration of the Alhambra monument and other Al-Andalus constructions. Initial results of archaeological campaigns, structure chronologies and communication plans undertaken in 2021 and 2022 are presented.
Contando Contágios: Arqueologia e História em Tempo(s) de Epidemia(s)
Authors: Wagner Gustavo Peretti , Da Silva Lucas Antônio 
Published: January 2025

Na presente proposta desenvolvemos uma reflexão acerca das epidemias e doenças que marcaram a história da humanidade. Através de uma abordagem de interlocução entre a arqueologia e a história, propusemos uma narrativa processual que abarcasse as epidemias, suas origens, dispersão e impactos nas transformações sociais: contamos contágios.
CONCEPTS ON ASYMPTOMATIC BACTERIAL VAGINOSIS
Authors: K. Telbiyska  , M. Angelova M. Angelova 
Published: January 2025

Bacterial vaginosis is a state of imbalance of the vaginal microbiota with prevalence of anaerobes and a relative lactobacilli deficit. The main pathogens are Gardnerella vaginalis species of heterogeneous phenotypic characteristics and virulence, forming a bacterial polymicrobial biofilm on vaginal epithelial cells.
A symptomatic infection clinically manifested by a homogeneous grey-white vaginal discharge with a fishy smell by all means requires a treatment regimen.
The concepts on asymptomatic bacterial vaginosis have not reached a definite consensus regarding the fact whether treatment is required – the interpretation of its sexual transmission is ambivalent and it is unclear whether there are any differences in the pathogenesis and levels of complications between the two clinical manifestations of bacterial vaginosis.
An early therapeutic approach is available for asymptomatic pregnant women; however, it does not demonstrate a significant difference in the incidence of obstetric complications.
Fluctuations and transitoriness in vaginal microbiota composition, manifested by spontaneous transition to verified lack of infection destabilizes the view point that treatment is mandatory in asymptomatic non-pregnant women. Recommendations are available concerning preoperative regimens, prevention of gynaecological and obstetric complications aiming at prevention of sexual transmission and infection with other sexually transmitted diseases.
The treatment approaches to verified bacterial vaginosis involving combined standard and alternative regimens have shown unsatisfactory long-term results, and the evidence so far is insufficient to absolutely confirm or refute the usefulness of treating an asymptomatic infection.
STUDY ON ANIMAL BONE MATERIAL EXCAVATED FROM AN ARCHEOLOGICAL SITE FROM THE EARLY CHALCOLITH AND THE LATE IRON AGE NEAR THE VILLAGE OF SREDETS, BULGARIA
Authors: D. Kostov  , D. Takorova  , P. Stoyanova  , H. Hristov  , D. Vladova  
Published: January 2025

The aim of the present research was to perform an archaeozoological analysis of animal bone material obtained from excavations near the village of Sredets, Stara Zagora region, Bulgaria. The osteoarchaeological finding was species-determined by morphological methods. The osteological material contained an entire skeleton of a sacrificed horse and 1015 species-determined bones and bone fragments belonging to a total of nine species of mammals of domestic and wild origin. The osteological finding from domestic mammals was predominant, amounting to 941 pieces of bones. The cattle bones took up a leading position of the total number of identified bones – 49,80% from the Early Chalcolithic Age and 58,14% from the Late Iron Age. The greater part comprised food remains from ancient inhabitants, indicated by the strong fragmentation of the animal bones, and traces of a mechanical impact as a result of an interaction with hard objects (portioning), as well as traces of thermal processing (burning). In a ritual pit from the Late Iron Age, a skeleton of a sacrificial horse was found. The horse was part of the livelihood and economic activity in these lands, marked the high social status of its owner, and, therefore, was sacrificed during funerals or other rituals.
PREVALENCE OF THE RESPIRATORY SYNCYTIAL VIRUS INFECTION IN THE WINTER AND SPRING MONTHS AMONG BULGARIAN CHILDREN YOUNGER THAN 2 YEARS OF AGE
Authors: E. Kostadinova  , S. Angelova  
Published: January 2025

Lower respiratory tract infections (LRTIs) in children from 2 months to 5 years of age are significant for clinical practice and researchers because of their high incidence, risk of severe clinical course, and development of chronic complications. About 60% of LRTIs are caused by viral infections. PURPOSE: To make an etiological diagnosis of viral infections of the lower respiratory tract-acute bronchiolitis and viral pneumonia. To present an epidemiological characterization in relation to the identified viral agents. METODS: The subjects of the prospective study were 101 children aged 2 months to 5 years, hospitalized in the Clinic of Pediatrics with clinical manifestations of viral LRTI`s with bronchial obstruction. Clinical material was analyzed according to the main epidemiological parameters: sex, age, place of residence, season, etiological agent of infection, etiological diagnosis according to season, presence of risk factors from family history and comorbidities. Etiological diagnosis of viral LRTIs was made by RT-PCR analysis. RESULTS: Epidemiological characteristics of the diagnosed viral LRTIs are presented. The prevalence of male sex was found to be higher (without statistical significance), more frequent among urban children and the highest incidence of viral LRTIs in the age up to 2 years. The etiological diagnosis made shows that respiratory syncytial virus (RSV) is the most common etiological cause of acute bronchiolitis in children under 2 years of age, both alone and in co-infections. CONCLUSIONS: RSV is the most common statistically significant etiological cause in winter and spring. Rhinovirus (RV) is the leading etiological cause in summer and autumn. Co-infections involving RSV and RV also have a high incidence during these seasons.
Temporal attentional bias to visual game stimuli in Internet gaming disorder
Authors: Hu Mengjian , Ku Yixuan , Liu Lu 
Published: January 2025

AbstractBackground and aimsUncontrollable gaming behavior is a core symptom of Internet Gaming Disorder (IGD). Attentional bias towards game-related cues may contribute to the difficulty in regulating online gaming behavior. However, the context-specific attentional bias and its cognitive mechanisms in individuals with IGD have not been systematically investigated.MethodsWe compared individuals with IGD to healthy controls (HC) using a rapid serial visual presentation (RSVP) task to measure temporal attentional bias. By applying game-related and neutral stimuli as targets, we specifically assessed how attentional resources were allocated to game-related stimuli compared to neutral stimuli.ResultsThe IGD group showed enhanced attentional blink effect when a game-related stimulus was the first target and a neutral target was the next, reflecting IGD's difficulty in disengaging from game-related stimuli. Both IGD and HC individuals exhibited decreased accuracy in identifying a neutral first target followed by a game-related second target at shorter lags, indicating increased attentional engagement with game-related stimuli in general.DiscussionThe results provide a cognitive basis for recurrent and uncontrollable gaming behaviors in individuals with IGD. Game cues have priority in the allocation of attentional resources in individuals with IGD. The results shed new light on the development of specific treatments for IGD.
Analysis of the persistent photoconductivity in composite nanocrystalline ZnO/Si films produced by co-sputtering at room temperature
Authors: Ortiz Vázquez Jonathan , Paredes Rubio Gabriel Romero , Arellano Miguel Galván , Castro Ontiveros Erick Ismael , Peña Sierra Ramón 
Published: January 2025

AbstractThe persistent photoconductivity (PPC) behavior in composite nanocrystalline films ZnO(RF)/Si(DC) films grown by co-sputtering was studied. The studied films were produced by fixing the ZnO RF magnetron power at 120 Watts and varying the DC power for the Si target from 0 to 80 Watts. The produced films were structural, optical, and electrical characterized; n-type films were produced for all the composition range. The PPC behavior was studied in samples grown with the composition formed with the ZnO (RF = 120 W)/Si (DC = 20 W) power condition, and by exposing the sample surfaces under continuous or pulsed ultraviolet (UV) radiation (390–400 nm). After applying an extended cleansing period, the PPC characteristic time constants, τ.63, were obtained; the turn-off time constant varied from 16.8 to 22.8 s, while the turn-on time constant changed from 24 to 30 s. These periods are linked to the UV light lattice absorption and the corresponding energy relaxation mechanisms.
Graphical abstract
Acute Decompensated Heart Failure: Structural and Functional Changes in Mitochondria
Authors: Garganeeva A. A. , Kuzheleva E. A. , Tukish O. V. , Vitt K. N. , Kondratiev M. Yu. , Syromyatnikova E. E. , Andreev S. L. , Arsenieva Yu. A. , Korepanov V. A. , Afanasiev S. A. 
Published: January 2025

Aim. Comparative assessment of structural changes in cardiomyocyte mitochondria of the right atrial appendage and the mitochondrial respiratory function in peripheral blood leukocytes in a cohort of patients after acute decompensated heart failure (ADHF) and with stable chronic heart failure of ischemic etiology with reduced ejection fraction (CHFrEF) or moderately reduced ejection fraction (CHFmrEF) of the left ventricle.Material and methods. The study analyzed 40 micrographs of right atrial appendage cardiomyocytes obtained from 12 patients with CHFrEF and CHFmrEF. The study protocol was registered on ClinicalTrials.gov: NCT05770349. Electron microscopy was performed with a JEM-1400 transmission electron microscope (Subdiffraction Microscopy Collective Use Center at the Electron Microscopy Department of the Belozersky Research Institute of Physico-Chemical Biology, Lomonosov Moscow State University). The total area of interfibrillar mitochondria was calculated as a ratio of the total surface area of mitochondria located between the cardiomyocyte contractile fibers to the total area of the interfibrillar space. The respiratory activity of isolated mitochondria was assessed in oxygenated standard incubation media. Patients were divided into two groups based on the occurrence of an ADHF episode within 12 months before inclusion in the study: Group 1 (n=19), patients without ADHF and Group 2 (n=21), patients with an episode of ADHF.Results. Most of the clinical and anamnestic parameters were comparable between the study groups. Analysis of the mitochondrial respiratory function in peripheral blood leukocytes showed reduced values of the respiratory control level (RCL) in both study groups, 2.14 [2; 2.32] and 2.55 [1.36; 2.84] conv. units. The total area of interfibrillar mitochondria was 41.7 [32; 58]% in the group without ADHF and 33 [21; 46]% in patients with ADHF (p=0.048); significant correlations were found between this parameter and the distance walked in the 6-min walk test (r=0.482; p=0.002) and the peak oxygen consumption during exercise (r=0.395; p=0.012). A ROC analysis was used to determine a threshold value of the total area of interfibrillar mitochondria in patients with ADHF: the cutoff point was 32%.Conclusion. A decrease in the total area of interfibrillar mitochondria of the right atrial appendage cardiomyocytes of less than 32% as measured by electron microscopy is characteristic of patients with a previous episode of ADHF with reduced and moderately reduced left ventricular ejection fraction. The study results confirm the development and persistence of ultrastructural changes in cardiomyocytes after ADHF.
Oxidized alkaline biochar and phosphate solubilizing bacteria mixture enhances direct seeded maize yield in an acid soil
Authors: Tusar Hachib Mohammad , Uddin Md. Kamal , Mia Shamim , Kasim Susilawati , Abd. Wahid Samsuri Bin , Makino Tomoyuki , Solaiman Zakaria 
Published: January 2025

Maize is an important cereal in many developed and developing countries of the world. One of the primary challenges for maize cultivation is soil acidity. Acidic soil is a major constrain in achieving food security requiring sustainable solutions. Biochar, a pyrogenic carbon-rich material, carries reactive surfaces (i.e., high surface area and variable surface charges). Therefore, it facilitates nutrient retention in soil and gradual release to plants, thereby supporting crop growth. However, the combine effects of functionalized biochar with microbes on phosphorus (P) bioavailability and plant performance remain unclear. This study investigates the application of different oxidized biochars (i.e.,fresh rice husk biochar (RHB), pH adjusted oxidized RHB and control) and phosphate solubilizing bacteria (i.e., <em>Pseudomonas aeruginosa</em>, and control) on soil properties including phosphorus dynamics and the performance of maize grown in an acid soil. Biochar was oxidized using 10% hydrogen peroxide while the pH was adjusted to 8.5. Maize was grown in pots having 20 kg of soil or soil-biochar mixture. Overall, biochar and microbes treatments increased soil phosphorus bioavailability and maize yield with a greater effects in the oxidized biochar giving a significant biochar × microbes interactions. Specifically, oxidized biochar when applied with <em>Pseudomonas aeruginosa</em> increased P availability by 380 % which then contributed to yield increment (291%). We also observed a significant reduction in available aluminum (Al) concentration (40% ) compare to the control. These improvement in yield might have occurred due to an increase soil pH, P bioavailability (r<sup>2</sup>= 0.74), and a reduction in Al toxicity (r<sup>2</sup>= 0.36).Findings of this study could have significant implications for crop production in acidic soil.
PERINGKASAN TEKS BERBAHASA INDONESIA MENGGUNAKAN TEKNIK EKSTRAKSI DENGAN ALGORITMA LATENT SEMANTIC ANALYSIS (LSA) DENGAN VARIASI TF-IDF UNTUK PERINGKASAN SINGLE DOCUMENT
Authors: Deki Riana  , Widodo  , Murien Nugraheni  
Published: January 2025

Perkembangan teknologi menyebabkan masyarakat mudah untuk mencari dan mendapatkan informasi. Banyaknya informasi yang disajikan menyebabkan masyarakat memerlukan penggalian informasi yang mencakup keseluruhan dokumen secara ringkas. Peringkasan dokumen dapat menyajikan inti dari dokumen secara singkat tanpa mengurangi esensi dokumen. Peringkasan single dokumen adalah peringkasan yang diekstrak dari satu dokumen. Terdapat banyak algoritma yang dapat digunakan untuk membuat sistem peringkas single dokumen otomatis. Salah satu algoritma tersebut adalah Latent semantic analysis (LSA). Serta algoritma yang umum digunakan dalam Text Processing adalah TF-IDF. Penelitian ini bertujuan untuk mengetahui kegunaan algoritma LSA dan TF-IDF untuk peringkasan single dokumen ilmiah berbahasa Indonesia. Bahan yang digunakan untuk penelitian ini adalah jurnal ilmiah berbahasa Indonesia sebanyak lima puluh (50) dokumen dengan topik yang sama yaitu “Natural language processing”. Penelitian ini menggunakan library NLTK dan Sastrawi untuk library corpus, stopword, dan stemming berbahasa Indonesia, kemudian hasil peringkasan menggunakan algoritma Latent semantic analysis (LSA) dengan variasi TF-IDF dievaluasi menggunakan Recall-Oriented Understudy for Gisting Evaluation (ROUGE-n). Hasil penelitian yang didapatkan menggunakan ROUGE-1 dari peringkasan otomatis oleh sistem menggunakan algoritma LSA dengan variasi TF-IDF adalah nilai presisi 0,713, recall 0,718, dan f-measure 0,715 untuk kompresi sebanyak 5 kalimat. Selanjutnya hasil optimal pada kompresi sebanyak 10 kalimat algoritma LSA dengan variasi TF-IDF didapatkan nilai optimal untuk presisi 0,680, recall 0,698, dan f-measure 0,689. Untuk kompresi sebanyak 20 kalimat algoritma LSA dengan variasi TF-IDF didapatkan hasil nilai optimal untuk presisi 0,752, recall 0,739, dan f-measure 0,745. Dapat disimpulkan ROUGE-1 didapatkan hasil pengujian optimal tertinggi dengan kompresi sebanyak 20 kalimat dengan nilai rata-rata presisi 0,529, recall 0,562, dan f-measure 0,538. Kemudian hasil optimal dihasilkan dengan kompresi sebanyak 10 kalimat dengan nilai rata-rata nilai presisi 0,493 recall 0, 518 dan f-measure 0, 499.
Total Elbow Arthroplasty for a Complex Proximal Radius and Ulna Fracture—A Case for Expanding Indications
Authors: Rees Andrew B. , Hodgens Blake H. , Connor Patrick M. 
Published: January 2025

Case:
We present a 79-year-old woman with a complex elbow fracture including a comminuted proximal ulna fracture, coronoid process fracture, and comminuted radial head fracture treated with primary total elbow arthroplasty (TEA). The patient completed an early therapy protocol and had complete healing. At 15 months postoperatively, she had full pronosupination and elbow arc of motion from 10 to 135° with no reported pain.

Conclusion:
Primary treatment of unstable, complex fractures of the proximal ulna and radius with TEA has not been previously reported in the literature. This case reports suggests that indications for primary TEA for traumatic elbow injuries in the elderly could be expanded.
Treatment of a Rare Case of Longitudinal Forearm Instability
Authors: Joseph Elias G , Cunningham Bryce A 
Published: January 2025

Case:
A 41-year old man fell from height sustaining displaced radial shaft and ulnar styloid fractures underwent open reduction internal fixation of the radius with early recognition of a radiocapitellar dislocation and longitudinal forearm instability in the early postoperative period. Revision surgery was performed 13 days postoperatively involving annular ligament reconstruction, elbow spanning external fixation, and distal radioulnar joint stabilization. Favorable functional and radiographic outcomes are shown at 1-year follow-up.

Conclusion:
Longitudinal forearm instability is associated with multiple patterns of forearm fractures. Early recognition of the injury with appropriate anatomic reconstruction likely results in improved outcome.
Radical Resection of a Radial Ewing Sarcoma and Ulnar Centralization in a 10-Month-Old Girl
Authors: Rehal Michael , Giacalone Joseph D. , Farrell Steven , Matalon Julia , Kopeld Jacob , Valverde Jorge , Rogers Michael P. , Wittig James C. 
Published: January 2025

Case:
We outline the management of a 10-month-old girl with an Ewing sarcoma involving the entire radius. The patient was treated with neoadjuvant chemotherapy resulting in almost a complete response. A limb-sparing procedure was performed consisting of a radical resection of the entire radius and centralization of the carpus to the ulna.

Conclusion:
This case is the first to describe an Ewing sarcoma of the entire radius in a 10-month-old girl treated with a radical resection of the radius and centralization of the carpus on the ulna. Over 2 years postoperatively, the construct remains stable with a very good functional and aesthetic outcome.
Comparison of Constrained Life Cycle Production Optimization Algorithms Based on Stochastic Simplex Approximate Gradients
Authors: Toktas Omer Lutfu , Nguyen Quang Minh , Onur Mustafa 
Published: January 2025

Summary
This study focuses on the optimization of net present value (NPV) with respect to well controls, such as injection rates and producing bottomhole pressures (BHPs), subject to the nonlinear constraints of field liquid production rate (FLPR) and water rate for producers (WWPR). The core challenge is to maximize NPV while adhering to both linear and nonlinear constraints, crucial for effective reservoir management. The research presents a detailed comparison of three sequential quadratic programming (SQP)-based optimizers—the Tulsa University nonlinearly constrained production optimizer (TU-NLCPO), our in-house nonlinear production optimizer, and two publicly available optimizers, namely sequential least squares programming optimizer (SLSQP), and sparse nonlinear optimizer (SNOPT)—highlighting their application in constrained life cycle production optimization, a key aspect of closed-loop reservoir management. These optimizers are evaluated based on their ability to handle optimization variables, such as BHPs and well injection rates, over fixed control steps. Stochastic simplex approximate gradient (StoSAG) is applied across the three algorithms for a fair comparison. This comparison is performed using the Brugge model for waterflooding, providing a rigorous real-world assessment of each optimizer’s performance. Our findings reveal that TU-NLCPO consistently achieves higher NPV compared with SLSQP and SNOPT, indicating its superior optimization capability. Additionally, TU-NLCPO and SLSQP are found to be robust against different initial guesses, demonstrating consistent NPV values, whereas SNOPT shows variability despite reasonable overall performance. Regarding optimization with nonlinear state constraints, the performances of three optimizers are highly dependent on the initial guesses. The study also explores the impact of varying the number of perturbations for stochastic gradient generation on optimizer performance, noting an improvement across all methods with more perturbations. In general, our results show that SNOPT requires more accurate gradients, that is, more StoSAG perturbations required, than the other two optimizers, SLSQP often requires scaling of the objective function, while TU-NLCPO is more robust as compared with SLSQP and SNOPT to different initial guesses with nonlinear state constraints.
WITHDRAWN: Agaricus blazei extract FA2bβ enhances the sensitivity of K562/ADR cells through the PI3K/Akt/mTOR signalling pathway
Authors: wang dongping , ge wanwen , sun yanqing 
Published: January 2025

Abstract

The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Coral records exaggerate past decadal tropical climate variability
Authors: Dolman Andrew , McPartland Mara , Felis Thomas , Laepple Thomas 
Published: January 2025

Abstract

Geochemical tracers measured in corals are a key archive for reconstructing past variations in tropical climate and provide unique information on the complex nature of global climate dynamics. However, reconstructions from tropical corals contain much greater decadal to centennial climate variability than evident from models or instrumental records, suggesting either biases in climate models or enhanced preindustrial climate variability. Using a method to distinguish climate from non-climate variations, on a global coral dataset, we show that records from single corals contain a strongly autocorrelated non-climate noise component. This noise inflates the reconstructed temperature variability by a factor of two to three across a large range of timescales, implying that past studies may have exaggerated decadal to centennial temperature variations.