bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histamine Recognition by Carbon Dots from Plastic Waste and Development of Cellular Imaging: Experimental and Theoretical Studies
Authors: Muro-Hidalgo Jessica M. , Bazany-Rodríguez Iván J. , Hernández José Guadalupe , Pabello Victor Manuel Luna , Thangarasu Pandiyan 
Published: March 2023

AbstractThe present work highlights the sustainable approach for the transformation of plastic waste into fluorescent carbon dots (CDs) through carbonization and then they were functionalized with L-cysteine and o-phenylenediamine. CDs which were characterized by different analytical techniques such as X-ray diffraction (XRD), thermogravimetric analysis (TGA), Scanning electron microscopy (SEM), and transmission electron microscopy (TEM) are employed to recognize Cu2+, Fe2+, and Hg2+ ions. The results show that the fluorescence emission was considerably quenched, and it is consistent with the interference and Jobs plots. The detection limit was found to be 0.35µM for Cu(II), 1.38 µM for Hg(II), and 0.51µM Fe(III). The interaction of CDs with metal ions enhances the fluorescence intensity detecting histamine successfully. It shows that plastic waste-based CDs can be applied clinically to detect toxic metals and biomolecules. Moreover, the system was employed to develop the cellular images using Saccharomyces cerevisiae cells with the support of a confocal microscope. Furthermore, theoretical studies were performed for the naphthalene layer (AR) as a model for C-dots, then optimized its structure and analyzed by using the molecular orbital. The obtained TD-DFT spectra coincided with experimental spectra for CDs/M2+/histamine systems.
Graphical Abstract
An approach to measure resilience of communities to climate change: a case study in Calabria (Southern Italy)
Authors: Antronico Loredana , Carone Maria Teresa , Coscarelli Roberto 
Published: March 2023

Abstract
Climate change effects already represent a serious challenge for people and environment. In particular, changes in precipitation, temperature, and weather systems are increasing the occurrence frequency of natural phenomena such as floods and landslides with consequent negative impacts in exposure and vulnerability of population living in risk areas. Hence, it is important to assess the social vulnerability and the community resilience which describe the ability of social systems to prepare for, absorb, and adapt to risks induced by climate change. In two sample areas located along the Tyrrhenian side of Calabria (Amantea and Lago municipalities, Southern Italy), we performed a multi-criteria decision analysis (MCDA) of community resilience. Based on previous literature, we have selected five macro-indicators of social resilience (awareness, knowledge, information, trust, and social background). As sub-indicators for the characterization of these macro-indicators, we used the answers of the questions on climate change effects of a questionnaire submitted to citizens living in the sample areas, and, then, a specific weight was assigned to each sub-indicator, as well as to the macro-indicators. The multi-criteria analysis allowed to the classification of the studied areas in terms of an index of social resilience and to the individuation of the most influential macro-indicators for each of them. The results show that the two areas, which have similar resilience’s values, are influenced by different macro-indicators: knowledge and awareness for Amantea and information and trust for Lago. The findings of this study can be considered very useful for the management of vulnerable areas to climate change, because they are able to underline the aspects needing attention. In fact, providing information about the nuances of the resilience of community exposed to risks may help decision-makers in adopting and implementing more effective preventive measures to mitigate negative effects of climate change, fitting on local characteristics.
The pattern of photosynthetic response and adaptation to changing light conditions in lichens is linked to their ecological range
Authors: Osyczka Piotr , Myśliwa-Kurdziel Beata 
Published: March 2023

AbstractEpiphytic lichens constitute an important component of biodiversity in both deforested and forest ecosystems. Widespread occurrence is the domain of generalist lichens or those that prefer open areas. While, many stenoecious lichens find shelter only in a shaded interior of forests. Light is one of the factors known to be responsible for lichen distribution. Nevertheless, the effect of light intensity on photosynthesis of lichen photobionts remain largely unknown. We investigated photosynthesis in lichens with different ecological properties in relation to light as the only parameter modified during the experiments. The aim was to find links between this parameter and habitat requirements of a given lichen. We applied the methods based on a saturating light pulse and modulated light to perform comprehensive analyses of fast and slow chlorophyll fluorescence transient (OJIP and PSMT) combined with quenching analysis. We also examined the rate of CO2 assimilation. Common or generalist lichens, i.e. Hypogymnia physodes, Flavoparmelia caperata and Parmelia sulcata, are able to adapt to a wide range of light intensity. Moreover, the latter species, which prefers open areas, dissipates the excess energy most efficiently. Conversely, Cetrelia cetrarioides considered an old-growth forest indicator, demonstrates definitely lower range of energy dissipation than other species, although it assimilates CO2 efficiently both at low and high light. We conclude that functional plasticity of the thylakoid membranes of photobionts largely determines the dispersal abilities of lichens and light intensity is one of the most important factors determining the specificity of a species to a given habitat.
Does the Ownership of Water Utilities Influence Water-Saving Advice Provided to Service Users? An Analysis of the Spanish Water Sector
Authors: López-Ruiz Samara , Ibáñez-Rueda Nazaret , Guardiola Jorge , González-Gómez Francisco 
Published: March 2023

AbstractThis paper addresses the need to ensure the sustainable use of water, in line with the United Nations’ Sustainable Development Goals. Using statistical methods, this paper analyses whether the ownership of the water utility is an explanatory factor for (1) the provision of water conservation advice on utilities’ websites; and (2) how comprehensive this advice is in terms of tips on (i) installing efficient technology and (ii) adopting sustainable habits and behaviours. The paper focuses on the Spanish water industry, which is considered particularly appropriate for the analysis due to the coexistence of utilities with different ownership structures. The results reveal statistically significant differences according to the ownership of the operator and the size of the population served. For example, more private companies provide some advice on their websites, while public companies offer more tips per online advice section. The evidence should encourage national governments and regulatory authorities to pass a regulation that establishes guidelines on how these companies, both public and private, should provide water conservation advice on their websites.
Salinity and temperature influence removal levels of heavy metals and chloride from water by wetland plants
Authors: Schück Maria , Greger Maria 
Published: March 2023

Abstract
Stormwater with low temperatures and elevated salinity, common in areas where deicing salt is used, might affect the removal of heavy metals by plants in stormwater treatment systems such as floating treatment wetlands. This short-term study evaluated the effects of combinations of temperature (5, 15, and 25 °C) and salinity (0, 100, and 1000 mg NaCl L−1) on the removal of Cd, Cu, Pb, and Zn (1.2, 68.5, 78.4, and 559 μg L−1) and Cl− (0, 60, and 600 mg Cl− L−1) by Carex pseudocyperus, C. riparia, and Phalaris arundinacea. These species had previously been identified as suitable candidates for floating treatment wetland applications. The study found high removal capacity in all treatment combinations, especially for Pb and Cu. However, low temperatures decreased the removal of all heavy metals, and increased salinity decreased the removal of Cd and Pb but had no effect on the removal of Zn or Cu. No interactions were found between the effects of salinity and of temperature. Carex pseudocyperus best removed Cu and Pb, whereas P. arundinacea best removed Cd, Zu, and Cl−. The removal efficacy for metals was generally high, with elevated salinity and low temperatures having small impacts. The findings indicate that efficient heavy metal removal can also be expected in cold saline waters if the right plant species are used.
New Psychoactive Substances in the Homeless Population: A Cross-Sectional Study in the United Kingdom
Authors: Coombs Thomas , Ginige Tilak , Van Calster Patrick , Abdelkader Amor , Corazza Ornella , Assi Sulaf 
Published: March 2023

Abstract
The last few years have seen the emergence of new psychoactive substance among the homeless population, specifically synthetic cannabinoid receptor agonists. The purpose of this study is to investigate the knowledge and experiences of new psychoactive substances amongst users from the homeless population. An explanatory research design was applied using a semi-structured questionnaire with the focus on gaining insights on the prevalence, motivations and effects. Participants were recruited through convenience sampling from support organisations and charities UK-wide. Descriptive statistics and logistic regression were applied to analyse the data obtained from participant surveys. A total of 105 participants met the inclusion criteria and were in the age range of 18 to 64 years old. Almost 70% consumed new psychoactive substance products, which “Spice” was the most prevalent substance. Homeless users had consumed new psychoactive substance to escape reality and to self-treat themselves and stopped consumption due to the adverse effects. Adverse events were reported from the majority of the participants and led to more than 20% of the participants requiring medical treatment following hospitalisation. Findings from this study can contribute to the development of guidelines and policies that specifically address the needs of the homeless population who use new psychoactive substances.
Digital Sequence Information and the Access and Benefit-Sharing Obligation of the Convention on Biological Diversity
Authors: Akpoviri Frank Irikefe , Baharum Syarul Nataqain , Zainol Zinatul Ashiqin 
Published: March 2023

AbstractWith the advent of synthetic biology, scientists are increasingly relying on digital sequence information, instead of physical genetic resources. This article examines the potential impact of this shift on the access and benefit-sharing (ABS) regime of the Convention on Biological Diversity (CBD) and the Nagoya Protocol. These treaties require benefit-sharing with the owners of genetic resources. However, whether “genetic resources” include digital sequence information is unsettled. The CBD conceives genetic resources as genetic material containing functional units of heredity. “Material” implies tangibility, and for some scholars, “functional units of heredity,” undefined in both treaties, mean full-coding sequences. This article argues that digital sequence information obtained from physical genetic resources, full-coding or not, should be treated as genetic resources. Literal construction of the CBD risks eroding its usefulness and the ABS regime. This is because through bioinformatics, sequence information can easily be obtained from genetic resources for utilization, without physically moving them or concluding ABS agreement with owners. The CBD must evolve with scientific progress also because sequence functionality depends on the state of knowledge. These arguments are vindicated by domestic ABS laws equating genetic information with genetic resources; Nagoya Protocol provisions deeming research exploiting the genetic composition of genetic resources as utilization of genetic resources; and CBD provisions requiring the sharing of benefits from the utilization of genetic resources. Moreover, treaty interpretation and case law demand that generic, scientific terms, such as “genetic resources” and “functional units of heredity” be interpreted in an evolutionary manner to capture scientific developments.
The role of digitalization in business and management: a systematic literature review
Authors: Calderon-Monge Esther , Ribeiro-Soriano Domingo 
Published: March 2023

AbstractDigitalization is a powerful engine for economic growth in the world. In 2018, digitally transformed firms represented 13.5 billion US dollars of global GDP and, towards the end of 2023, they are expected to represent 53.3 billion US dollars, over half of the general nominal GDP (Statista, Nominal GDP driven by digitally transformed and other enterprises worldwide 2018–2023.https://www.statista.com/statistics/1134766/nominal-gdp-driven-by-digitally-transformed-enterprises/, 2022). The main objective of this study is to provide information (highlighting principal research topics and research agendas) from the literature on state-of-the-art digitalization within firms through a Systematic Literature Review (SLR). In all, 119 review articles on the most mature functional areas of the firm are analyzed: management, marketing, and finance and accounting, published in the WOS over the period 2018-April 2022. In this study, key relevant tendencies are identified in the most mature areas of the firm, which are the impact of digital technologies on the analysis of consumer behavior; digitalization and green innovation within organizations; and blockchain technology applied to financial services. The main contributions of this work are as follows: (1) to provide the most complete and up-to-date review of digitalization from a global perspective, summarizing the current state of knowledge within an integrated framework; (2) to reduce the complexity of digitalization by offering structure and clarity; and (3) to offer links between digitalization and established points of view in the literature on management, marketing, finance, and accounting. The novelty of this paper is centered on a joint analysis of digitalization, digital transformation, and digital technologies, taking into account the most mature functional areas of the firm.
The role of management control and integrated information systems for the resilience of SMEs
Authors: Roffia Paolo , Dabić Marina 
Published: March 2023

AbstractThis paper investigates the resilience of small and medium-sized enterprises (SMEs) in relation to the COVID-19 pandemic, particularly the influence exerted by certain factors related to management control, integrated information systems (enterprise resource planning [ERP]), information and communication technology (ICT) systems, and financial resources. For this purpose, leveraging from the dynamic capability theory, in late spring 2020, a questionnaire was sent to limited-liability SMEs in Verona and Vicenza provinces in Italy operating in the manufacturing, construction, and distribution sectors. Respondents were asked to answer a set of questions and to evaluate the resilience of their firms as of January 1, 2020; May 1, 2020; and one year later, as of July 2021. Using a multivariate regression model to analyze data from the 143 questionnaires received, we found a positive influence of budgeting, business continuity tools, availability of supplementary financial resources, and resilience of the entrepreneur on both COVID-19 resilience and the organizational resilience of SMEs. SMEs with a high intention to use ERP systems also had high resilience levels. ICT use for smart working was not statistically significant. Despite the limitations concerning the sample and period considered, we believe that this study contributes to both academic debate, by illustrating the influence of certain managerial and organizational factors on the resilience of SMEs, and practice, by supporting a greater empirical use of management control tools, such as budgets and contingency plans, and integrated information systems (ERP). Our study supports the creation of financial buffers and strengthening the entrepreneur’s resilience for improving SME resilience.
Clinical characteristics of pediatric allogeneic hematopoietic stem cell transplantation-associated thrombotic microangiopathy (TA-TMA): a retrospective single-center analysis
Authors: Luo Linlin , Xiong Hao , Chen Zhi , Yang Li , Sun Ming , Lu Wenjie , Tao Fang , Wang Zhuo , Li Jianxin , Li Zuofeng , Tang Sujie 
Published: March 2023

Abstract
Objectives
To investigate the clinical features of thrombotic microangiopathy associated with allogeneic hematopoietic stem cell transplantation in children.

Methods
A retrospective analysis of continuous clinical data from HSCT received in the Department of Hematology and Oncology of Wuhan Children's Hospital from August 1, 2016 to December 31, 2021.

Results
During this period, 209 patients received allo-HSCT in our department, 20 (9.6%) of whom developed TA-TMA. TA-TMA was diagnosed at a median of 94 (7–289) days post-HSCT. Eleven (55%) patients had early TA-TMA within 100 days post-HSCT, while the other 9 (45%) patients had TA-TMA thereafter. The most common symptom of TA-TMA was ecchymosis (55%), while the main signs were refractory hypertension (90%) and multi-cavity effusion (35%). Five (25%) patients had central nervous system symptoms (convulsions and lethargy). All 20 patients had progressive thrombocytopenia, with 16 patients receiving transfusion of platelets that was ineffective. Ruptured red blood cells were visible in only two patients with peripheral blood smears. Cyclosporine A or Tacrolimus (CNI) dose was reduced once TA-TMA was diagnosed. Nineteen cases were treated with low-molecular-weight heparin, 17 patients received plasma exchange, and 12 patients were treated with rituximab. TA-TMA-related mortality percentage in this study was 45% (9/20).

Conclusion
Platelet decline and/or ineffective transfusion post-HSCT should be considered an early indicator of TA-TMA in pediatric patients. TA-TMA in pediatric patients may occur without evidence of peripheral blood schistocytes. Aggressive treatment is required once diagnosis is confirmed, but the long-term prognosis is poor.
Physical activity habits and their effects on quality of life in patients with addiction: data from the Czech Republic
Authors: Köhlerová Michaela Zahrádka , Fišerová Zdeňka , Páv Marek 
Published: March 2023

AbstractAddiction, including substance use disorder (SUD), is a complex condition that can cause serious health problems and negatively affect patient quality of life. Physical activity is known to improve the physical and mental health of patients with SUD. This study aims to determine the relationship between regular physical activity (RPA) and quality of life in SUD patients enrolled in inpatient SUD treatment (n = 159). We divided patients into four groups based on their RPA before and during hospitalization. The SF-36 self-report questionnaire was used to assess quality of life. We found that SUD patients had worse quality of life than a representative sample of the Czech population. Furthermore, we demonstrated that RPA before and during hospitalization and changes during hospitalization affect the perception of quality of life of patients with SUDs. Additionally, physically active patients showed significantly better quality of life than inactive patients. However, patients who initiated RPA during hospitalization reported worse quality of life than those who did not; in addition, this group of patients reported the worst quality of life across the most monitored parameters. We suggest that these patients represent the most vulnerable group. Changes in physical activity habits could be considered an indicator for a more intensive therapeutic focus.
Humiliation and state anxiety as predictors of attenuated psychosis in a community sample
Authors: Toh Wei Lin , Lee Stuart J. , Rancie Tim , Penita Phaybian , Moseley Peter , Rossell Susan L. 
Published: March 2023

AbstractExisting literature suggests that humiliation experiences, coupled with a negative family context, significantly predicts persecutory ideation in non-clinical participants. Whether this may also be linked to attenuated psychotic experiences is unknown. The current study aimed to assess whether familial adversity and humiliation may be related to hallucination-like experiences (HLEs) and other psychotic symptoms, and if state anxiety significantly contributed to these relationships. This cross-sectional study recruited a community sample of 93 adults (38% male; mean age = 27.3 years, standard deviation = 10.8 years), who completed measures of maladaptive familial environments, past and anticipated humiliation experiences, state anxiety and attenuated psychotic symptoms. Correlations and hierarchical regressions tested for direct and indirect relationships amongst study variables. A maladaptive family context, and humiliation (past and anticipated) were positively correlated with HLEs, and facets of attenuated psychotic symptoms. Anxiety uniquely predicted audio-visual and multisensory HLEs. Past humiliation and anxiety jointly predicted cognitive-perceptual disturbance and disorganisation, whereas fear of humiliation and anxiety jointly predicted interpersonal difficulty. Elevated state anxiety, coupled with humiliation, may increase attenuated psychotic symptoms in adulthood. Future research is needed to ascertain if these relationships hold true in clinical cohorts to examine the clinical significance of these data.
Merging Minds: The Conceptual and Ethical Impacts of Emerging Technologies for Collective Minds
Authors: Lyreskog David M. , Zohny Hazem , Savulescu Julian , Singh Ilina 
Published: March 2023

AbstractA growing number of technologies are currently being developed to improve and distribute thinking and decision-making. Rapid progress in brain-to-brain interfacing and swarming technologies promises to transform how we think about collective and collaborative cognitive tasks across domains, ranging from research to entertainment, and from therapeutics to military applications. As these tools continue to improve, we are prompted to monitor how they may affect our society on a broader level, but also how they may reshape our fundamental understanding of agency, responsibility, and other key concepts of our moral landscape.In this paper we take a closer look at this class of technologies – Technologies for Collective Minds – to see not only how their implementation may react with commonly held moral values, but also how they challenge our underlying concepts of what constitutes collective or individual agency. We argue that prominent contemporary frameworks for understanding collective agency and responsibility are insufficient in terms of accurately describing the relationships enabled by Technologies for Collective Minds, and that they therefore risk obstructing ethical analysis of the implementation of these technologies in society. We propose a more multidimensional approach to better understand this set of technologies, and to facilitate future research on the ethics of Technologies for Collective Minds.