bluuebunny/crossref_metadata_2025_split huggingface dataset:
The frequency of hypertension and other risk factors in patients undergoing large joint arthroplasty: a real-world study
Authors: Okisheva E. A. , Madoyan M. D. , Fidanyan S. E. , Semenova A. I. , Panferov A. S. , Mironova O. Iu. , Lychagin A. V. , Fomin V. V. 
Published: March 2023

Background. The population of patients undergoing large joints arthroplasty has a high prevalence of comorbidities, such as hypertension and other cardiovascular diseases, obesity, diabetes, chronic kidney disease, etc., that are independent risk factors for the postoperative complications, especially of the thromboembolic events.Aim. To evaluate the prevalence of hypertension and other risk factors in patients undergoing large joint arthroplasty in real-world practice.Materials and methods. The study included an unselected sample of patients (n=82) who underwent arthroplasty of large joints in December 2022 at the Clinic of Traumatology, Orthopedics and Joint Pathology of the I.M. Sechenov First Moscow State Medical University. A detailed history was collected from all patients and, if necessary, a laboratory and instrumental examination was performed to assess the presence of target organ damage.Results. Sixty-two patients (81.7%) had hypertension; among them 12.6% had no previous antihypertensive therapy. The average body mass index (BMI) was 31.3±5.2 kg/m2 confirming the high prevalence of obesity in this population. All obese patients had concomitant hypertension (n=62), and 6 people (7.3%) with a BMI over 40 kg/m2 had signs of obstructive sleep apnea syndrome. Diabetes mellitus (DM) was diagnosed in 13 people (15.9%); in all cases it was type 2 diabetes. Chronic kidney disease (CKD) stage 2-4 was diagnosed in 67 people (81.7%), and all these patients had concomitant obesity and hypertension.Conclusion. Based on the analysis of published literature and a sample of patients from real-world practice, the main population undergoing the arthroplasty of large joints include elder patients, and the vast majority of them have multiply comorbidities (obesity, hypertension, CKD) that are not only the independent risk factors for poor prognosis, but also exacerbate the other concomitant conditions and further increase the risk of complications. It is necessary to conduct large prospective studies with specific evaluation of various cohorts of patients undergoing arthroplasty of large joints including a pharmacoeconomic analysis to determine the need and scope of further examination in this population with a high risk of perioperative complications.
Psychédélisme raté. De quelques relations entre musique expérimentale, sommeil et autosabotage
Authors: Dunoyer de Segonzac Thomas 
Published: March 2023

Si vous avez eu la chance de dormir debout pendant un concert dans une salle comme les Instants Chavirés (Paris), le Buffet Froid (Grenoble) ou la Cave 12 (Genève), ou de laisser votre esprit chavirer jusqu’à ne plus rien remarquer de ce qui se jouait vraiment sur scène, vous vous en souvenez peut-être aussi, comme nous, comme l’un de vos meilleurs souvenirs de musique. Recevoir ce texte de Thomas Dunoyer de Segonzac, auteur pour Revue & Corrigée et taulier du label No Lagos, fut un petit moment d’émotion en plein lent déconfinement, à rapprocher du visionnage du documentaire « Le rock aux Instants Chavirés (ou comment en finir avec le jazz) » d’Yves-Marie Mahé (disponible en ligne). La musique est parfois là pour abolir la musique. On peut habiter avec elle un espace où la poésie, l’émeute, la conscience modifiée, et la conversation d’à côté ne sont plus dans les marges — et où ces marges ont envahi le centre. On y est bien.
De l’ œconomia à l’échange volontaire : la délimitation de l’activité économique chez Thomas d’Aquin
Authors: Januard Pierre 
Published: March 2023

La pensée économique de Thomas d’Aquin est connue pour son apport concernant le juste prix ou l’usure, mais sa délimitation épistémologique de l’activité économique retient peu l’attention des commentateurs. L’Aquinate hérite d’Aristote de la notion d’ œconomia , gestion familiale se distinguant à la fois du politique, qui concerne la cité, et de l’activité du marchand, pour « le gain » ou « pour l’argent ». La délimitation de l’activité économique se fait donc par l’agent et par la finalité. Jusqu’à la Somme de théologie , le traitement des activités économiques est dispersé dans ses œuvres. La Somme fait œuvre novatrice en adoptant une typologie objectiviste, par la nature de l’opération, ici l’échange. Elle regroupe ces activités d’échange, à savoir le commerce et le prêt, en deux questions contiguës et leur donne un prologue commun. Elle les réunit comme échanges volontaires et nomme les péchés qui s’y rapportent. Thomas délimite ainsi l’activité économique, qui doit étre un échange et un acte volontaire. Ce cadre est à la fois extensif et restrictif : il permet de rendre compte des cas limites comme l’échange de biens non marchands, mais il exclut ce qui se rapporte à un don sans contrepartie, ou à un échange effectué avec secret (vol) ou violence (rapine). Ces critères, loin de constituer des évidences, viennent interroger les lectures économiques de l’œuvre thomasienne et la compréhension des rapports asymétriques entre co-contractants.
Shaping, and disinfecting abilities of ProTaper Universal, ProTaper Gold, and Twisted Files: A correlative microcomputed tomographic and bacteriologic analysis
Authors: Sivakumar Malavika , Nawal Ruchika Roongta , Talwar Sangeeta , Baveja CP , Kumar Rega , Yadav Sudha , Kumar S Santosh 
Published: March 2023

ABSTRACT

Aim:
The purpose of this study was to assess the canal shaping ability and reduction of Enterococcus faecalis (E. faecalis) by ProTaper Universal (PTU), ProTaper Gold (PTG), and Twisted File (TF) systems, using microcomputed tomography (µCT).

Methods:
Distobuccal canals of 36 extracted human maxillary molars were inoculated with E. faecalis American Type Culture Collection 29212 for 28 days. Thirty-three specimens (three excluded due to contamination) were randomly divided into three groups with 11 specimens in each group, according to the instrumentation system that was utilized: PTU, PTG, and TF. Sterile distilled water was used as the irrigant during preparation. Paper points had been used to collect samples from the root canals both pre- and postpreparation, and bacterial quantification was done to examine the bacterial reduction. Pre- and postinstrumentation µCT scanning of roots were done to analyze the shaping ability.

Results:
After preparation, all three techniques significantly lowered the amount of E. faecalis while also significantly increasing the canal volume (P < 0.001). Intergroup comparison of the % of bacterial reduction and uninstrumented area disclosed no significant differences (P > 0.05), whereas the increase in canal volume of the PTU was significantly higher than PTG and TF, and that of the PTG was significantly higher than TF.

Conclusion:
It may be concluded, within the constraints of this in vitro study, that PTG and TF had better shaping ability than PTU, whereas no difference was found in their ability to reduce bacterial load.
Comparative evaluation of fracture resistance of simulated immature teeth restored with apical plugs of mineral trioxide aggregate, Biodentine, and bone cement: An in vitro study
Authors: Gudapati Swapnika , Satish R Kalyan , Sajjan Girija S , Varma K Madhu , Kumar V Santosh , Kumar M Sitaram 
Published: March 2023

ABSTRACT

Aim:
This in vitro study aimed to compare the fracture resistance of simulated immature permanent teeth restored with apical plugs of mineral trioxide aggregate (MTA), Biodentine, and bone cement.

Methods:
Forty-eight single-rooted human maxillary central incisors were selected and decoronated 6 mm above and 9 mm below the cementoenamel junction to simulate the immature teeth. Based on weight and homogeneity, the samples were distributed into three experimental groups (n = 12) and one control group (n = 12). In all the experimental group samples, a peeso reamer size 5 was stepped out 1 mm beyond the apex to enlarge the apices to a diameter of 1.5 mm. Apical plugs of MTA Plus (Prevest DenPro Limited, India), Biodentine (Septodont, France), and Bone cement (Surgical Simplex P, Stryker, Australia) were placed to 4 mm, and obturation was done using gutta-percha and AH Plus® sealer (Dentsply DeTrey, Konstanz, Germany). The force was applied at 45° angulation until fracture, using the universal testing machine. The results were analyzed using a one-way analysis of variance followed by Tukey’s post hoc test at a 95% confidence level.

Results:
The Biodentine group showed a statistically higher fracture resistance value than the MTA Plus and bone cement group (P = 0.014 and P = 0.016, respectively). No statistically significant difference was reported between MTA Plus and the bone cement group.

Conclusion:
Within the limitations of this study, using Biodentine as an apical plug increases the fracture resistance of immature teeth. Bone cement can be used as a viable alternative to MTA.
Estimating the Burden of Tuberculosis in India: A Modelling Study
Authors: Mandal Sandip , Rao Raghuram , Joshi Rajendra 
Published: March 2023

Background:
Measurements TB incidence and mortality are crucial for monitoring progress towards SDG goals for TB. Until recently, WHO estimated TB burden in India with applied simple, transparent equilibrium models to data from Gujarat, an Indian state where the first state-level prevalence survey was conducted in 2011. However, since then there has been several interventions in India including national TB prevalence survey, infection survey, sub-national survey & certification which gives opportunity for national and sub-national estimates for TB incidence and mortality.

Methods:
We developed a model is a compartmental, deterministic framework, taking account of TB natural history, as well as India’s healthcare system including health care seeking from public and private sector. To address changes in TB burden owing to COVID disruptions, we followed same model that used by WHO in the global TB Report 2022 with additional impact of delta wave in 2021. Major sources of data included National TB Prevalence survey, trends in caseloads in public and private sector including their contribution and mortality information.

Results:
We estimated total TB incidence of 2.77 million in the year 2022 as against 2.97 in the year 2015 and corresponding TB mortality of 0.32 and 0.36 million respectively. In terms of rate per 1,00,000 TB incidence in 2022 was 196 as compared to 225 in the year 2015 and mortality was 23 and 27 respectively. TB incidence estimates are similar to what was estimated by WHO, while mortality estimates appear different in our estimates due to different calibration targets depending on in-country published data.

Conclusion:
Even if TB burden is infeasible to measure directly, a range of data can nonetheless offer indirect evidence for its estimation: mathematical modelling can be a helpful tool for bringing together these diverse sources of evidence, and deriving estimates that are consistent with them all. While the RGI reported mortality is an important source of information, its quality and coverage for medically certified cause of deaths requires improvement in India.
The Economic Freedom Fighters of South Africa:What do they Stand for, and who Votes for them?
Authors: Mtimka Ongama , Prevost Gary 
Published: March 2023

The Economic Freedom Fighters (EFF) have emerged as a significant force in South African politics during the past eight years. Still, only a few scholarly studies have been published analysing its ideology, strategy, and tactics, who is voting for the party, and why. The authors argue that the EFF had emerged as a challenger to the African National Congress (ANC) by positioning itself to the left of the ruling party with a set of ideas and policy proposals that emerged from the ANC Youth League when current EFF leader Julius Malema led it. Survey and exit polling data analysed by the authors indicate that the EFF is gaining traction election by election with younger black voters in the townships on issues of land and jobs and, in the process, threatens the single-party dominance of the ANC in future South African elections. However, despite a good start, the party appears to have lost some momentum after the fall of former President Jacob Zuma and made some tactical mistakes.
Comparative impact of Covid-19 and common diseases on poverty in Cameroon and sustainable response strategies
Authors: Defo Charles Michel Chomssem 
Published: March 2023

In the context of a developing country like Cameroon characterized by the scarcity of financial resources and the appearance of Covid-19, this article shows that this pandemic was not more important than the pre-existing health problems to the point of giving it more importance in funding compared to strengthening the health system. The theoretical elasticity model of the poverty rate to growth is used to estimate the impact of Covid-19 and the incidence of impoverishing health expenditure is used for the impact of common diseases. It is estimated through direct health payments that common diseases push about 340,865 people into extreme poverty annually. The Covid-19, through the loss of growth generated between 4.8 and 6.6 points according to the optimistic or pessimistic scenarios, would impoverish between 224,193 and 398,565 people: impact on the number of poor ranging from 0.7 to 1.2 times that of all common diseases, i.e., equivalent on average, but sensitive to the speed of spread of the virus and the duration of the crisis while the impact of common diseases is structural and linked to the poorly performing health system. The solutions proposed are endogenous and linked to the impact mechanisms.
Assessment Of Adenoid Nasopharyngeal Ratio In Children With Symptoms Suggestive Of Obstructive Adenoid Disease
Authors: Dahilo E.A. , Itanyi U.D. , Yikawe S.S. , Folorunsho D.F. , Ibekwe T.S. 
Published: March 2023

Background: Adenoid hypertrophy (AH) is a common childhood illness that occurs due to obstruction of the nasopharynx by enlarged adenoids. Lateral nasopharyngeal X-ray is used for diagnosis and assessment of patency of the nasopharyngeal air column by assessing the Adenoid Nasopharyngeal Ratio (ANR). This study aims to assess the ANR of symptomatic patients with AH that presented to Ear, Nose and Throat/ Head and Neck Surgeon (ENT/HNS) Department of the University of Abuja Teaching Hospital (UATH).
Methodology: This was a retrospective study conducted in the ENT/HNS Department of UATH, Gwagwalada from January 2019 to December 2021. The case notes and lateral nasopharyngeal xrays of 112 children aged between 3 months to 15 years, diagnosed with Adenoid Hypertrophy, were retrieved. Relevant information such as demographics, and Lateral Nasopharyngeal X-ray measurements were extracted.
Results: A total number of 112 participants were enrolled into this study. Out of these, 77 (68.8%) were males and 35 (31.2%) were females. The mean age of participants was 3.86 0.27 years, and age range was 3 months to 15 years. Most participants were between 0 – 5 years. The mean ANR among participants was 0.69 0.02. The minimum ANR was 0.03, and the maximum ANR was 1.00 Majority of participants had ANR 0.69. None of the participants between 10 – 15 years had an ANR > 0.79. Regression analysis showed statistically significant correlation between ANR and Age (p = 0.05).
Conclusion: We observed an Adenoidal Nasopharyngeal Ratio that was lower than the benchmark of ANR considered for AH, this may probably be due to our inability to control the timing for obtaining the radiographs from clinic visit and some may have commenced treatment
Hàm Cobb-Douglas hay hàm Translog? Nghiên cứu thực nghiệm tại Việt Nam
Authors: Cảnh Trần Quang , Phức Vũ Trực 
Published: March 2023

Trong kinh tế học và kinh tế lượng, hàm sản xuất Cobb-Douglas và hàm Translog thường được sử dụng rộng rãi để biểu thị mối quan hệ kỹ thuật giữa lượng của hai hoặc nhiều yếu tố đầu vào và lượng đầu ra. Tuy nhiên, theo khảo lược từ các nghiên cứu trước thì đa phần đều sử dụng hàm Cobb-Douglas, cũng có một số nghiên cứu sử dụng hàm Translog hoặc cả hai hàm trong một nghiên cứu. Tuy nhiên, việc so sánh kết quả phân tích của hai dạng hàm này hầu như chưa được đề cập đến.
Bài viết này sử dụng số liệu thống kê đầu vào là GDP Việt Nam từ 2009 - 2019, thực hiện phân tích bằng cả hai hàm Cobb-Douglas và Translog. Kết quả nghiên cứu cho thấy từ việc so sánh độ lệch chuẩn, so sánh đồ thị giá trị dự báo với đồ thị của giá trị thực tế và các chỉ số Mean Absolute Error (MAE), Mean Abs. Percent Error (MASE), Root Mean Squared Error (RMSE), Theil Inequality Coefficient (Theil) đều thể hiện kết quả dự báo bằng hàm Translog cho kết quả đáng tin cậy hơn so với dự báo bằng hàm Cobb-Douglass.
Effects of Nutrient Media Including Heavy Metals at Different Concentrations in In Vitro Conditions on the Growth of Squash (Cucurbita pepo L.)
Authors: MANCAK Zeki , BAKTEMUR Gökhan 
Published: March 2023

Squash (Cucurbita pepo L.) is a vegetable species that is appreciated and consumed in
the Türkiye world and in the world. Its cultivation is carried out both in the open field and
greenhouse. Heavy metals create adverse conditions for all living things due to their toxic effects.
In this study, key heavy metals like aluminum (Al), cadmium (Cd), cobalt (Co), lead (Pb) and nickel
(Ni) were added to the nutrient medium (Murashige and Skoog-MS)at different concentrations (0,
100, 200, 300, 400 and 500 μM). Squash seeds were germinated under in vitro conditions. During
the research, the number of leaves and roots, stem and root lengths were determined. According to
the results, the number of leaves was the highest in the control group for all heavy metals. The
number of roots decreased as the heavy metal concentration increased. While stem length reached
the highest number in all heavy metals in the control group, root lengths had the lowest levels at 400
and 500 μM doses. Considering these results, it has been revealed that as the dose of heavy metals
increases, the growth of the plant is retarded.
Discovery in Balinese Shadow Puppet Shows
Authors: Marajaya I Made 
Published: March 2023

The purpose of this article is to examine discovery in relation to the creativity of Balinese shadow puppet show agents. Since time immemorial, there has been nothing new in the creativity of Balinese shadow puppet shows. However, it turns out that there is novelty and discovery in the development of Balinese shadow puppet shows. The problems are: 1) Why does the puppeteer innovate in the Balinese shadow puppet show?; 2) What is the form of discovery in the Balinese shadow puppet show?; 3) Is there an impact of discovery in the Balinese shadow puppet show? This problem has been investigated using qualitative methods. Discovery elements related to creativity in Balinese shadow puppet performances have been observed, and a literature study has been carried out based on publications about Balinese shadow puppets. All data were analyzed qualitatively using practical theory and aesthetic theory from a cultural studies perspective. The results of the study show that: 1) responding to market demands, cultural influences from modern society, technological sophistication, and the need for creativity and artist training for Balinese shadow puppet performances; 2) there is a condensation of the performance structure accompanied by a simplification of the language of the puppeteers, variations in the movements of the puppet characters, variations of light, variations of sound, and new apparatus are discoveries in Balinese shadow puppet performances; and 4) the discovery of the Balinese shadow puppet show has had an impact on Balinese puppet artists and art.
Keywords : Discovery, Creativity, Shadow Puppet Show, Bali.
Topological Data Analysis of COVID-19 Using Artificial Intelligence and Machine Learning Techniques in Big Datasets of Hausdorff Spaces
Authors: Onyango Allan , Okelo Benard , Omollo Richard 
Published: March 2023

In this paper, we carry out an in-depth topological data analysis (TDA) of COVID-19 pandemic using artificial intelligence (AI) and Machine Learning (ML) techniques. We show the distribution patterns of pandemic all over the world when it was at its peak with respect to big data sets in Hausdorff spaces. The results show that the world areas which experience a lot of cold seasons were affected most.

Received: 31 January 2023 | Revised: 6 March 2023 | Accepted: 21 March 2023

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
No effects on heart rate variability in depression after treatment with dorsomedial prefrontal intermittent theta burst stimulation
Authors: Bengtsson Johan , Olsson Erik , Persson Jonas , Bodén Robert 
Published: March 2023

Background: The purpose of this study was to investigate whether treatment of a depressive episode with intermittent theta burst stimulation (iTBS) over the dorsomedial prefrontal cortex (DMPFC) had any effects on heart rate variability (HRV). We also investigated if changes in HRV covaried with symptom change after iTBS and if HRV could predict symptom change.
Methods: We included 49 patients with a current depressive episode. All were randomized to receive a double-blind treatment course with active or sham iTBS over the DMPFC. HRV data were obtained from 1 h of night data before and after the iTBS. The standard deviation of the RR interval (SDNN) was chosen as primary outcome measure. Depressive, negative, and anxiety symptoms as well as self-rated health were assessed by clinicians or by self-report.
Results: The group×time linear mixed model revealed no effect of iTBS on SDNN (estimate = −1.8, 95% confidence interval [CI]: −19.9 to 16.2). There were neither correlations between HRV and depressive, negative, or anxiety symptom change after iTBS nor with self-assessed health. No predictive value of HRV was found.
Conclusions: Treatment for depression with dorsomedial iTBS had neither negative nor positive effects on the cardiac autonomic nervous system.
KHẢO SÁT ĐỘT BIẾN GEN FLT3, NPM1, CEBPA Ở NGƯỜI BỆNH BẠCH CẦU CẤP DÒNG TỦY MỚI CHẨN ĐOÁN TẠI BỆNH VIỆN TRUYỀN MÁU HUYẾT HỌC VÀ BỆNH VIỆN CHỢ RẪY
Authors: Lại Thị Thanh Thảo , Châu Thúy Hà , Nguyễn Trường Sơn , Phù Chí Dũng , Hoàng Anh Vũ , Phan Thị Xinh 
Published: March 2023

Đặt vấn đề: Bạch cầu cấp dòng tủy (BCCDT) là bệnh lý ác tính của tế bào đầu dòng tủy và là bệnh không đồng nhất cả về hình thái lẫn tiên lượng. Các bất thường gen và nhiễm sắc thể giúp phân nhóm nguy cơ trước điều trị. Khảo sát đột biến các gen FLT3, NPM1 và CEBPA ở người bệnh bạch cầu cấp dòng tủy có ý nghĩa thực tiễn và khoa học. Đối tượng và phương pháp: Mẫu tủy xương hoặc máu ngoại biên của 248 người bệnh BCCDT mới chẩn đoán tại bệnh viện Truyền máu Huyết học và bệnh viện Chợ Rẫy được thu nhận để khảo sát đột biến gen FLT3, NPM1 và CEBPA bằng kỹ thuật giải trình tự Sanger. Kết quả: Chúng tôi ghi nhận tỉ lệ người bệnh mang đột biến NMP1, FLT3 và CEBPA lần lượt là 29,4%, 24,2% và 19,8%. Đột biến FLT3 gồm 14,9% là FLT3-ITD, 6,5% là FLT3-TKD và 2,4% là đột biến khác. Đột biến FLT3-ITD có đoạn lặp và vị trí chèn đoạn đa dạng. Đột biến type A của gen NPM1 gặp trong đa số các trường hợp (83%). Trong các ca mang đột biến CEBPA, có 11,6% trường hợp mang 1 loại đột biến và 8,2% người bệnh mang 2 kiểu đột biến. Có 11/23 người bệnh mang 2 kiểu đột biến CEBPA được chuyển gen vào T-vector để xác định đột biến trên 1 hay 2 alen, và ghi nhận có 5/11 người bệnh (45,5%) mang đột biến trên 2 alen. Các đột biến gen FLT3, NPM1, CEBPA có thể xuất hiện riêng lẻ hoặc xuất hiện đồng thời. Kết luận: Đây là 3 gen có tần suất đột biến cao ở người bệnh BCCDT. Việc xuất hiện đột biến của chúng mang ý nghĩa tiên lượng, vì vậy cần triển khai khảo sát thường quy trong thực hành lâm sàng để phân nhóm tiên lượng và lựa chọn điều trị thích hợp.