bluuebunny/crossref_metadata_2025_split huggingface dataset:
The status and childcare management of overweight and obesity among preschool children in Hangzhou
Authors: Hu Ye , Qian Xia , Chen Jinqing , Huang Dan 
Published: August 2023

Abstract

Objectives
This study aims to investigate the prevalence of overweight and obesity in preschool children in Hangzhou and assess the impact of childcare management. By examining the characteristics and predicting the trends of overweight and obesity, we hope to emphasize the significance of childcare management in primary community health service centers and the use of Electronic Health-care System in kindergartens. This study also seeks to provide evidence for intervention measures and effective prevention and control management of childhood obesity.

Methods
From 2020 to 2022, kindergarten children aged 3–6 years old were selected as the research objects in kindergartens in Hangzhou. The Electronic Health-care System will be utilized to facilitate the management of childhood obesity and provide guidance and training to pediatricians and Primary Care Physicians.

Results
The overall detection rates of overweight and obesity were 7.27 % and 3.55 %, respectively, among children aged 3–6 years in Hangzhou. The rates of simple obesity in Hangzhou preschool children aged 3–6 years were 4.25 , 3.42, and 3.04 % from 2020 to 2022, respectively; the overweight detection rates of children were 8.27 , 7.28, and 6.34 %, respectively, and the difference was statistically significant (p<0.05). The detection rates of overweight and obesity in 2022 were significantly lower than those in 2020 (p<0.05). The prevalence of obesity in children increased with age. Boys had a significantly higher incidence rate of obesity than girls (p<0.05). The proportion of children with moderate and severe obesity showed a downward trend. Intervention measures for childhood obesity in primary community health service centers and kindergartens are constantly being implemented.

Conclusions
The prevalence of obesity in preschool children aged 3–6 years in Hangzhou exhibited a decreasing tendency. This research has identified that child care administration, particularly the implementation of the Electronic Health-care System, demonstrates effectiveness in handling overweight and obesity amongst children.
Deep learning empowering design for selective solar absorber
Authors: Ma Wenzhuang , Chen Wei , Li Degui , Liu Yue , Yin Juhang , Tu Chunzhi , Xia Yunlong , Shen Gefei , Zhou Peiheng , Deng Longjiang , Zhang Li 
Published: August 2023

Abstract
The selective broadband absorption of solar radiation plays a crucial role in applying solar energy. However, despite being a decade-old technology, the rapid and precise designs of selective absorbers spanning from the solar spectrum to the infrared region remain a significant challenge. This work develops a high-performance design paradigm that combines deep learning and multi-objective double annealing algorithms to optimize multilayer nanostructures for maximizing solar spectral absorption and minimum infrared radiation. Based on deep learning design, we experimentally fabricate the designed absorber and demonstrate its photothermal effect under sunlight. The absorber exhibits exceptional absorption in the solar spectrum (calculated/measured = 0.98/0.94) and low average emissivity in the infrared region (calculated/measured = 0.08/0.19). This absorber has the potential to result in annual energy savings of up to 1743 kW h/m2 in areas with abundant solar radiation resources. Our study opens a powerful design method to study solar-thermal energy harvesting and manipulation, which will facilitate for their broad applications in other engineering applications.
The coordination chemistry and supramolecular interactions of 2-(2′-Pyridyl)imidazole ligand: a comprehensive review with theoretical insight
Authors: Singha Debabrata , Halder Sasthi Charan , Jana Atish Dipankar , Pal Nilasish 
Published: August 2023

Abstract
This review explores the role of 2-(2′-Pyridyl)imidazole (PyimH) as a coordinating ligand and also its role as a supramolecular agent through hydrogen bonding and π⋯π interaction. Two N coordination sites make 2-(2′-Pyridyl)imidazole an analogous ligand to 2,2′-bipyridine. The syn orientation of imidazole and pyridine sp

2
nitrogen makes it a bidentate chelating ligand. PyimH mainly produces discrete coordination complexes (0D), but in a few cases, 1D coordination polymers are observed due to bridging co-ligands like oxalate, dicyanamide, tricyanomethanide, croconate, thiocyanate, and iso-thiocyanate. These discrete coordination units and co-ligand bridged 1D coordination polymers are further augmented to higher dimensional supramolecular systems having linear, zig-zag, ladder-shaped, ribbon-like, and helical geometry. These supramolecular structures are stabilized by intermolecular hydrogen bonding interaction (N–H⋯N, N–H⋯O, O–H⋯N, O–H⋯O, and C–H⋯O) and π⋯π interaction capability of PyimH ligand. PyimH generally acts as an excellent chelating ligand for a range of metal ions and is also a capable supramolecular glueing agent due to hydrogen bonding and π-stacking ability.
JAM’ AL TAKSĪR DALAM AL QUR’AN JUZ 1-10 (ANALISIS MORFOSINTAKSIS).
Authors: Maghfiroh Luthfirif'atul , Elmubarok Zaim , Multazam Multazam 
Published: August 2023

Jama' taksīr included the classification of Arabic nouns in number. The jama' taksīr classification in morphogenetic studies discuss processes of formation, cases, changes in grammatical bookmarks, and syntax functions. The research aims to describe the form of jama' taksīr in the qur 'an in juz 1-10 and explain the jama' taksīr analysis in the juz 1-10 of qur'an reviewing morphogenetic studies. It is a descriptive study with a qualitative approach. The study used content analysis as a research study. The data in this study is the written data of fragments of qur'an containing the jama' taksīr. Data collection techniques are conducted with predetermined elemental computing techniques, their tools being the mental effects of researchers. Research instruments are the researchers themselves aided by data cards. The study uses inductive data analysis techniques. The research found 94 data of jama' taksīr, consisting of 33 data of qillah (minor plural), 43 data of 'kasrah (major plural). According to syntax function, there are three cases in the JAM’ AL TAKSĪR analysed data, comprise 23 counts, 33 archivists, and 38 genetical-case data
Molecular characterization of the follicular development of BMP15-edited pigs
Authors: Jiao Yafei , Jiang Tiantuan , Lin Qiyuan , Guo Jinming , Bei Chang , Cong Peiqing , Mo Delin , Liu Xiaohong , Chen Yaosheng , He Zuyong 
Published: August 2023

In brief
The regulatory role of BMP15 on porcine ovarian follicular development still remains unclear. This study reveals that biallelic editing of BMP15 impairs SMAD signaling and inhibits granulosa cell proliferation, resulting in porcine follicular development arrest and ovarian hypoplasia.

Abstract
Bone morphogenetic protein 15 (BMP15) is a member of the transforming growth factor beta (TGF-β) superfamily, which is critical for facilitating ovarian folliculogenesis in mono-ovulatory mammalian species but is not essential in polyovulatory mice. Our previously established BMP15-edited pigs presented varied female reproductive phenotypes, suggesting the important role of BMP15 in ovarian folliculogenesis in polyovulatory pigs. To understand the regulatory mechanism underlying the effect of BMP15 on porcine ovarian follicular development, we molecularly characterized infertile biallelic-BMP15-edited gilts with ovarian hypoplasia. We found that an absence of BMP15 proteins in biallelic-BMP15-edited gilts can lead to premature activation of primordial follicles, possibly through the upregulation of KITLG-KIT-PI3K-AKT signaling pathways. However, this absence severely impaired SMAD (Sma and Mad proteins from Caenorhabditis elegans and Drosophila, respectively) signaling, causing severely reduced granulosa cell proliferation, leading to the arrest of follicular development during the preantral stage and ovarian hypoplasia, resulting in complete infertility. Our study expands the understanding of the molecular functions of BMP15 in nonrodent polyovulatory mammals.
Murine models of advanced maternal age: a systematic review and meta-analysis
Authors: Dalton-O’Reilly Jessica , Heazell Alexander E P , Desforges Michelle , Greenwood Susan , Dilworth Mark 
Published: August 2023

In brief
Animal models have been developed to aid understanding of the increased incidence of adverse pregnancy complications observed in women of advanced maternal age (AMA). This systematic review of murine models of AMA demonstrates consistent effects of decreased litter size and fetal weight; this supports the future use of these models to determine pathophysiological mechanisms and test therapeutic strategies to improve poor pregnancy outcomes in AMA.

Abstract
Advanced maternal age (AMA; ≥35 years of age) is associated with an increased risk of adverse pregnancy outcomes. To explore causes of adverse pregnancy outcomes in AMA, and to test candidate therapies, an increasing number of murine AMA models have been developed. The aim of this study was to systematically review the literature to assess whether murine AMA models demonstrate a reproducible effect on pregnancy outcomes. PubMed, Ovid, Web of Science and Google Scholar were searched. Studies that reported on pregnancy outcomes in AMA mice and rats were included; the SYstematic Review Centre for Laboratory animal Experimentation (SYRCLE) tool evaluated the risk of bias. Eleven mouse and six rat studies were included. AMA mice and rats had reduced litter size (standardised mean difference (SMD): −1.59, 95% confidence interval (CI): −1.84, −1.34 for mice; SMD: −1.66, 95% (CI): −2.09, −1.23 for rats) and reduced fetal weight (SMD: −0.87, 95% CI: −1.24, −0.49 for mice; SMD: −1.05, 95% CI: −1.40, −0.69 for rats). Placental weight was increased in AMA mice (SMD: 0.62, 95% CI: 0.16, 1.08). Subgroup analysis indicated that C57Bl/6 mice had less heterogeneity than other, mostly outbred, mouse strains with regards to litter size (C57 strain I2 = 68.2% vs other strain types I2 = 85.7%). The risk of bias was high, mostly due to the lack of methodological detail and unclear reporting of findings. Murine models of AMA demonstrate similar adverse pregnancy outcomes to those observed in large human epidemiological studies. The reproducible phenotypes in AMA murine models allow the exploration of mechanisms underpinning poor pregnancy outcomes and the pursuit of therapeutic interventions.
Principios de desarrollo de Índices de Ancestralidad para taxones biológicos
Authors: Espósito Sandoval Elián M. 
Published: August 2023

Antecedentes. Históricamente en biología ha habido discrepancias a la hora de considerar a ciertos taxones dentro de las categorías “nativo” o “exótico” en determinadas áreas geográficas.
Preguntas y/o hipótesis. ¿Tienen los taxones cualidades inherentes que permitan establecer formalismos concordantes con un principio de prioridad como criterio para resolver los problemas derivados de la categorización “nativo-exótico”?
Sitio y años de estudio: Tres áreas asociadas geográficamente pero con características discordantes fueron seleccionadas. Este trabajo se realizó entre 2017 y 2022.
Métodos: Se proponen dos tipos de índices complementarios. El “Índice de Ancestralidad Binario”, que parte de la distinción clásica de especie “nativa-exótica” y se codifica en forma binaria. El “Índice de Ancestralidad Escalar”, que se basa en el desarrollo de dos criterios: uno espacial (“distancia al área de origen”) y otro temporal (“tiempo de permanencia”).
Resultados: Se obtuvieron tablas con los índices mencionados para las especies y áreas elegidas.
Conclusiones: Estos índices resultarán útiles, por ejemplo, cuando sea necesario tomar decisiones que puedan afectar negativamente a los ecosistemas, considerando la historia e identidad del sitio. Los índices también serían fundamentales como estímulo a investigaciones de temáticas asociadas y para componerlo que se propone como estratigrafía ecológicade un área.
Estado del arte de las Investigaciones en Proyectos Ambientales Escolares (PRAE) en Colombia
Authors: Espinosa Rojas Diana , Castaño Barrera Óscar Mauricio 
Published: August 2023

En Colombia, desde 1974 se inicia la incorporación de la educación ambiental en el sector formal educativo; desde el 2002 el país cuenta con la Política Nacional de Educación Ambiental (PNEA) que direcciona los Proyectos Ambientales Escolares (PRAE) en las instituciones de educación básica y media que fueron instituidos originalmente en el decreto 1743 de 1994. El objetivo de éste artículo es presentar una revisión del estado del arte de las investigaciones realizadas alrededor de los Proyectos Ambientales Escolares (PRAE) para visualizar un panorama general de las mismas, los campos investigativos emergentes y los vacíos de conocimiento frente a este respecto. Esta no es una revisión de los PRAE sino de las investigaciones que se han llevado a cabo cuyo objeto de investigación hayan sido los PRAE.
Para lograr este objetivo, se realizó la búsqueda de artículos científicos y tesis publicados en bases de datos de internet desde el 2002 (fecha en la cual es emitida la PNEA) utilizando como descriptor principal el concepto de “Proyecto Educativo Ambiental”. Se realizó una clasificación preliminar de los artículos de acuerdo con sus objetivos principales y se encontraron seis categorías. Se encontró que la mayor cantidad de publicaciones se han realizado sobre “propuestas” y “caracterizaciones y diagnósticos” y las de menos publicaciones son las de “Propuestas de evaluación” y “experiencias de transversalización”.
Aprendizaje Significativo de las interacciones ecológicas que se presentan entre los organismos vivos en los ecosistemas de la Institución Educativa Barrio Santa Margarita (IEBSM)
Authors: Galeano Marín Juan David 
Published: August 2023

El presente artículo da cuenta de una estrategia de enseñanza fundamentada en la Teoría del Aprendizaje Significativo Crítico (TASC), de Moreira (2010) y secuenciada según el Ciclo Didáctico propuesto por Jorba y Sanmartí (1996). El referente conceptual correspondiente a las interacciones ecológicas, se construye a partir de una síntesis de las propuestas de Audesirk, Audesirk, & Byer (2013) y Curtis, & Schnek (2008).

Los estudiantes se organizaron en equipos de trabajo con roles específicos, tratando de propiciar el trabajo colaborativo en el desarrollo de una unidad de aprendizaje con actividades diversas como la lectura, la construcción de un mapa mental, el recorrido por las zonas verdes y la grabación y edición de un video tipo documental sobre las interacciones biológicas que se observaron en los ecosistemas de la Institución Educativa Barrio Santa Margarita.

La estrategia de enseñanza es potencialmente motivante, debido a que se usaron diversos materiales y estrategias educativas, mediante las cuales los estudiantes pudieron asumir un papel más activo en su proceso de aprendizaje. Debido a que los participantes tuvieron la posibilidad de percibir y representar en su contexto las interacciones ecológicas, considerando su importancia para el equilibrio de los ecosistemas, la propuesta, puede constituirse en un aporte a la enseñanza de una ética ambiental o un sistema de valores ambientales, lo cual puede conllevar a la construcción de nuevos modelos mentales que sean más coherentes con el respeto por todos los seres vivos y los ecosistemas. Adicionalmente, el uso de recursos TIC puede favorecer un Aprendizaje Significativo Crítico (ASC), en tanto posibilita diversificar los recursos educativos y las estrategias didácticas. Es aceptable que las TIC por si solas no constituyen una razón para lograr un aprendizaje significativo, pero cuando están inmersas en un contexto favorable facilitan el logro de los objetivos propuestos (Cobo, 2010).
Blockchain Enabled Decentralized Application for Securing Electronic Medical Records with Smart Contracts
Authors: PAKKALA RITHESH , B SHAMANTHA RAI , R AKHILA THEJASWI , RAI PRAKHYATH 
Published: August 2023

Abstract
The Electronic Medical Records of patients maintained needs to be ensured that privacy is preserved and must be accessible to authorized users such as doctors. Most of the health care systems use the traditional centralized database platforms for these data management; which is neither secure nor easy to maintain. These platforms can be replaced by distributed, efficient, and much more secure platforms which are backed by blockchain technology. In this work, a Decentralized application (dApp) is developed which allows users to upload and download medical data to and from the distributed file storage system. The application’s logic is written in solidity programming language in the smart contract. The application uses IPFS – Interplanetary File System, which is a distributed file storage system to store the medical records. Each file is broken down into pieces and each piece is given a hash which is stored on the blockchain. The user with right authentication has the privilege to access these hashes on the blockchain helping them in downloading the desired file. The application is tested through different nodes on the network which successfully resulted in securely storing and downloading the files from the distributed network. The results envision that the data stored in the IPFS is immutable, distributed across its network which makes it impossible for anyone to just access it. The dApp developed is tested with two performance metrics i.e. the number of transactions per unit time and the time taken to search records in the blockchain network and also the scalability issue pertaining to blockchain is also discussed.
Multi-temporal morphological analysis coupled to seismic survey of a mass movement from southern Italy: a combined tool to unravel the history of complex slow-moving landslides
Authors: Gioia Dario , Corrado Giuseppe , Amodio Antonio Minervino , Schiattarella Marcello 
Published: August 2023

Abstract
Impressive and large-scale slow-moving landslides with a long-term evolutionary history of activity and dormancy are a common landform in the southern Apennines mountain belt. The spatial and temporal evolution of a multi-stage complex landslide located in a catchment of the frontal sector of the southern Apennine chain was reconstructed by multitemporal geomorphological analysis, near-surface seismic survey, and DEM comparison. The Tolve landslide shows a multi-decadal evolution characterized by intermittent periods of activity and dormancy. Geomorphological evidences suggest that the initial failure of the large-scale landslide has a multi-millennial age and can be related to a roto-translational movement that evolved in an earthflow. Recent evolution is associated with a major reactivation event in the middle and lower sectors of the larger complex landslide, which probably is related to a heavy rainfall event occurred in January 1972. Recent evolution is mainly associated with minor movements in the source area, toe advancements, and widespread shallow landslides along the flank of the earthflow. Our results demonstrate the need to integrate traditional geomorphological analysis with multi-source data to reconstruct the evolution of slow-moving landslides and to identify their main predisposing and triggering factors.
Statistical analysis plan for the phaco TIp position during clear corneal Phacoemulsification Surgery (TIPS) randomized controlled trial
Authors: Kaup Soujanya , Kondal Dimple , Shivalli Siddharudha , Buchan John 
Published: August 2023

Abstract
Background
Cornea is the most important refractive media in the eye and damage to the corneal endothelium is one of the most common causes of poor visual outcome following cataract surgery, particularly in those with predisposing factors. The role of phaco tip position during phacoemulsification on corneal endothelial damage is ambiguous and there is no consensus regarding the most cornea-friendly phaco tip position (bevel-up or bevel-down). The objective of the trial is to compare the effect of phaco tip position (bevel-up vs. bevel-down) during phacoemulsification using direct chop technique on corneal endothelial cell count.
Methods and design
TIPS is a randomised, multicentre, parallel-group, triple-masked (participant, outcome assessor, and statistician) trial with 1:1 allocation ratio. A total of 480 eligible participants, aged >18 years with immature cataract will be randomly allocated into bevel-up and bevel-down groups at two centres. Randomisation will be stratified according to the cataract grade. The primary outcome is postoperative endothelial cell count at one month. Secondary outcomes are central corneal thickness on postoperative days 1, 15, and 30, and difference in intraoperative complications.
Conclusion
In this paper, we describe the detailed statistical analysis plan (SAP) for the TIPS trial, which was prepared prior to database lock. The SAP includes details of planned analyses and unpopulated tables, which will be reported in the publications. We plan to lock the database in July 2023 and publish the results later in the same year.
SAP Version 0.1 (Dated:28.04.2023)
Protocol version:2.0
Trial registration
Clinical Trial Registry of India CTRI/2019/02/017464. Registered on 5 February 2019;
https://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=29764&EncHid=&userName=2019/02/017464
Experiment and optimization of axial air-suction roller seed metering device
Authors: Zhang Yuqian , Yang Wencai , Zhang Chengyao , Zhang Haidong 
Published: August 2023

Abstract
The seed metering device construction is adjusted to improve the negative pressure at the seed metering device type hole and hence the seed suction efficiency. To explore the link between the structural parameters of the seed metering device and the negative pressure of the type hole, the Response Surface Methodology (RSM) is integrated with Computational Fluid Dynamics (CFD). Grid independence was tested to assure the solution's dependability. The internal flow field of the seed metering device was investigated, and the negative pressure at the type hole's input was 56.71 Pa. The Central Composite Design (CCD) in the response surface method was employed to generate a more perfect negative pressure at the suction of the type hole. The diameter of the air chamber channel, the draft angle of the type hole, and the number of fan blades were employed as design factors, and the major target function was the negative pressure at the entrance of the type hole. According to regression research, the optimal point occurs when the air chamber channel diameter is 59.26mm, the draft angle of the type hole is 14.28°, and the number of fan blades is 9. The objective function predicts a negative pressure of 69.41 Pa at the type hole's inlet. The Central Composite Design (CCD) in the response surface method was employed to generate a more perfect negative pressure at the suction of the type hole. The diameter of the air chamber channel, the draft angle of the type hole, and the number of fan blades were employed as design factors, and the major target function was the negative pressure at the entrance of the type hole. According to regression research, the optimal point occurs when the air chamber channel diameter is 59.26mm, the draft angle of the type hole is 14.28°, and the number of fan blades is 9. The objective function predicts a negative pressure of 69.41 Pa at the type hole's inlet.