bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Tanda dan Makna pada Desain Logo Sanggar Tari Puspitasari
Authors: Nurfitri Rina 
Published: January 2023

Logo tersebut memiliki nilai estetika sesuai dengan unsur-unsur seni yang terdapat pada desainnya. Keunikan dari logo puspitasari adalah berhubungan dengan ciri khas dari sanggar tersebut. Logo menjadi penentu atau bahkan sebagai simbol keberadaan suatu tempat pelatihan. Logo yang digunakan pada Puspitasari terdiri dari logotype dan logogram. Hal ini terlihat pada penggunaan teknik lettering yang dikombinasikan dengan elemen gambar. Logo Pupitasari didominasikan oleh tulisan karena mengandung kata, huruf, slogan. Dari klasifikasi bentuk yang terdapat pada logo, dai segi konstruksinya Puspitasari termasuk pada picture mark sekaligus lettermark. Tanda tersebut saling melengkapi dengan kombinasi penggunaan logogram dan logotype sudah dapat dikatakan mewakili dari identitas sanggar tari Puspitasari. Ciri khas yang ditampilkanpada logo tersebut mewakili dari bentuk tubuh sang penari dan lambing kelopak bunga mewakili dari nama sanggar tari tersebut yaitu sanggar tari Puspitasari.
Retrospective Analysis of COVID-19 Vaccination in a University Hospital and the Relationship with the Epidemic Rate
Authors: Alıravcı Işıl Deniz , Gümüşer Fatma , Şener Alper 
Published: January 2023

It was aimed to make a retrospective analysis of the vaccines administered in the vaccine unit of our hospital since the beginning of the COVID-19 pandemic. The study was carried out retrospectively from the vaccination records our hospital, 14 January 2021 to 01 July 2022. In the 18-month period, a total of 75079 (100%) vaccines were administered, 59386 (79%) were Biontech and 15693 (21%) were Sinovac vaccines. Only Sinovac was available until June, therefore, 66% of the Sinovac vaccines were administered in the first five months period. After the Biontech vaccine started to be applied in our hospital, the rates of Sinovac vaccination have declined drastically. When the epidemic and vaccination graphs were examined separately, inverse correlation was found between the peak points of the epidemic and vaccine graphics. Biontech was found to be the most preferred vaccine by individuals against COVID-19 in this study.
Суспільно-політична діяльність поляків Уманського повіту початку ХХ ст. у висвітленні газети «Киевлянин»
Authors: Kuznets Tetiana 
Published: January 2023

Метою статті є аналіз виявлених у губернській газеті «Киевлянин» публікацій про суспільно-політичну діяльність поляків Уманського повіту початку ХХ ст. Це сприятиме кращому розумінню глибинної сутності польсько-російського антагонізму, який посилювала імперська влада для зменшення польських політичних впливів.
Наукова новизна роботи полягає у тому, що увиразнено оцінку консервативною (у досліджуваних хронологічних межах) губернською газетою «Киевлянин» російської імперської політики щодо суспільно-політичної активності поляків у роки виборів до Державної думи та формування виборних земств. З’ясовано, що на шпальтах газети акцентувалась увага на прагненні імперської влади обмежити участь поляків у політичному процесі, залишивши їм єдине поприще вияву активності – діяльність у місцевих земствах.
Висновки. З’ясовано, що губернська газета «Киевлянин», яка виходила великим накладом і поширювалась по усьому Південно-Західному краєві, публікувала матеріали про російсько-польський антагонізм на інкорпорованих українських територіях. Публікації про суспільно-політичну діяльність поляків на початку ХХ ст. у межах одного повіту дали підстави зробити висновок, що русифікаторська політика імперії була спрямована на зменшення польських політичних впливів. Сприятливим часом для розвитку активності поляків були роки виборів до Державної думи – першого представницького органу влади в Російській імперії та формування виборних органів місцевого самоврядування – земств. Опубліковані у 1906-1912 рр. на шпальтах «Киевлянина» матеріали про участь поляків повіту у цих процесах доповнюють знання про сутність політики деполонізації. Участь поляків у суспільно-політичному житті регулювалася такими важелями як заборона укладання угод під час виборів до Державної думи та запровадження польської та російської курії під час формування виборних земств. Російська влада для активної діяльності поляків залишала тільки участь у місцевих земствах. Риторика газетних публікацій з цього приводу вказує на співчутливу оцінку консервативним «Киевлянином» можливостей участі поляків у суспільно-політичному житті на українських землях початку ХХ ст.
Стратегії виживання єврейського духовенства в радянській Україні в 1920–1930-х роках
Authors: Savchuk Tetiana , Ihnatusha Olexandr 
Published: January 2023

Мета дослідження – визначити зміст і зміни стратегій виживання юдейського духовенства в радянській Україні в умовах суспільних трансформацій 1920–30-х рр.
Методологія дослідження включає поєднання макро- та мікроісторичних підходів для реконструкції повсякдення єврейського духовенства. Застосовано біографічний метод для показу життєвих траєкторій окремих представників юдейського духовенства та з’ясування впливу суспільно-політичних подій на формування їх соціальної поведінки.
Наукова новизна полягає в історичній реконструкції стратегій виживання юдейського духовенства в Україні протягом 1920-30-х рр. Показано залежність зміни цих стратегій від форм і способів тиску державно-політичної влади та сили етноконфесійних традицій у середовищі єврейської спільноти.
Висновки. На формування стратегій виживання юдейського духовенства в Україні протягом 1920-30-х рр. впливало посилення й урізноманітнення суспільно-політичних викликів, що були результатом зміцнення тоталітарної системи. Особливо відчутними в середовищі юдейського духовенства були зміни соціальної та національної політики у формі голодоморів, пониження соціальних стандартів, посилення антирелігійного тиску, політичних репресій. У 1920-х рр. умови суспільно-політичного життя були ще відносно сприятливими для малочисельного єврейського духовенства. Затребуваність релігійних послуг, авторитет рабинів і канторів у громадах були факторами підтримки соціального становища служителів.
Основними стратегіями виживання юдейського духовенства визначено: слідування етнокультурним традиціям всупереч наростаючому політичному тиску, пошук додаткових господарських занять, отримання допомоги від громади та родини. Культ родини в єврейському соціумі обумовлював тісні взаємозв’язки її членів, що мінімізувало психологічний та економічний тиск атеїзованого суспільства.
Форсування політичного наступу влади на єврейську спільноту на межі 1920-30-х рр. формувало нові стратегії фізичного самозбереження. Юдейське духовенство вимушено відмовлялося від релігійної діяльності, інтенсивно шукало допомоги за кордоном, однак державне адміністрування та репресії комуністичної влади, руйнація нею етноконфесійної інфраструктури стали чинниками обмеження зв’язку євреїв України із закордоном, а відтак – і обсягів їх зовнішньої економічної підтримки. Одним із основних шляхів виходу юдейського духовенства з політичного безправ’я стала еміграція, на яку наважувалися, передусім, члени родин юдейського духовенства. У 1930-х рр. влада заблокувала цей гуманітарний коридор, формуючи тоталітарне суспільство в котлі сталінської модернізації.
Cyclodextrin-Based Nanosponges: Overview and Opportunities
Authors: Utzeri Gianluca , Matias Pedro M. C. , Murtinho Dina , Valente Artur J. M. 
Published: January 2023

Nanosponges are solid cross-linked polymeric nano-sized porous structures. This broad concept involves, among others, metal organic frameworks and hydrogels. The focus of this manuscript is on cyclodextrin-based nanosponges. Cyclodextrins are cyclic oligomers of glucose derived from starch. The combined external hydrophilicity with the internal hydrophobic surface constitute a unique “microenvironment”, that confers cyclodextrins the peculiar ability to form inclusion host‒guest complexes with many hydrophobic substances. These complexes may impart beneficial modifications of the properties of guest molecules such as solubility enhancement and stabilization of labile guests. These properties complemented with the possibility of using different crosslinkers and high polymeric surface, make these sponges highly suitable for a large range of applications. Despite that, in the last 2 decades, cyclodextrin-based nanosponges have been developed for pharmaceutical and biomedical applications, taking advantage of the nontoxicity of cyclodextrins towards humans. This paper provides a critical and timely compilation of the contributions involving cyclodextrins nanosponges for those areas, but also paves the way for other important applications, including water and soil remediation and catalysis.
Ionization of HCCI Neutral and Cations by Strong Laser Fields Simulated With Time Dependent Configuration Interaction
Authors: Schlegel H. Bernhard , Hoerner Paul , Li Wen 
Published: January 2023

Graphical AbstractTime-dependent configuration interaction simulations of the electron dynamics in coherent superpositions of the X and A cation states of HCCI show marked differences in the strong field ionization rates by intense, 2 cycle probe pulses that depend on the initial phase of the superposition and on the carrier envelope phase.
Oxygen Plasma Modified Carbon Cloth with C=O Zincophilic Sites as a Stable Host for Zinc Metal Anodes
Authors: Jiang Baozheng , Liu Wenbao , Ren Zhilong , Guo Rongsheng , Huang Yongfeng , Xu Chengjun , Kang Feiyu 
Published: January 2023

Aqueous zinc-ion batteries (ZIBs) are currently receiving widespread attention due to their merits of environmental-friendly properties, high safety, and low cost. However, the absence of stable zinc metal anodes severely restricts their potential applications. In this work, we demonstrate a simple oxygen plasma treatment method to modify the surface state of carbon cloth to construct an ideal substrate for zinc deposition to solve the dendrite growth problem of zinc anodes. The plasma treated carbon cloth (PTCC) electrode has lower nucleation overpotential and uniformly distributed C=O zincophilic nucleation sites, facilitating the uniform nucleation and subsequent homogeneous deposition of zinc. Benefiting from the superior properties of PTCC substrate, the enhanced zinc anodes demonstrate low voltage hysteresis (about 25 mV) and stable zinc plating/stripping behaviors (over 530 h lifespan) at 0.5 mA cm−2 with 15% depth of discharge (DOD). Besides, an extended cycling lifespan of 480 h can also be achieved at very high DOD of 60%. The potential application of the enhanced zinc anode is also confirmed in Zn|V10O24·12H2O full cell. The cells with Zn@PTCC electrode demonstrate remarkable rate capability and excellent cycling stability (95.0% capacity retention after 500 cycles).
Rapid diagnosis of non-tuberculous mycobacterial pulmonary diseases by metagenomic next-generation sequencing in non-referral hospitals
Authors: Wang Jing , Xu Huan , Wang Xi , Lan Jian 
Published: January 2023

ObjectivesThe incidence of non-tuberculous mycobacterial pulmonary disease (NTM-PD) has increased steadily globally, but the current culture-based diagnosis of NTM-PD is difficult and time-consuming, leading to a high possibility of misdiagnosis. Therefore, new methods should be introduced to improve the processes for clinical diagnosis of this disease.MethodsOur retrospective observational study enrolled 12 NTM-PD patients who were identified by way of metagenomic next-generation sequencing (mNGS), as well as the characteristic radiological presentation of slowly progressed, usually concomitant bronchiectasis, small cavitary opacity, and multiple nodules that respond poorly to empirical antibiotic therapy. These patients received the recommended drug regimen based on the identified non-tuberculous mycobacteria (NTM) species. Clinical data, including symptoms, laboratory tests, dynamic computed tomography imaging, treatment, and outcome, were recorded and analyzed.ResultsThe results of mNGS were all positive, with the standard specifically mapped read numbers (SDSMRN) of NTM ranging from 1 to 766; this was confirmed in six patients via quantitative polymerase chain reaction (qPCR) analysis. The duration fromsample collection tomNGS results was 1–4 days. Among our 12 patients (except for one lost to follow-up) the CT imaging for 11 patients showed significant absorption of lesions.ConclusionsOur results draw attention to NTM infection as a possible cause of community-acquired pneumonia, especially in patients with suggestive radiological presentation and poor responses to empirical antibiotic therapy. Our study also indicated that mNGS represented a potentially effective tool for the rapid identification of NTM in the respiratory sample. Improved clinician awareness combined with the utilization of mNGS could guide earlier diagnosis and targeted treatment, and finally improved the prognoses of patients with NTM-PD.
Evaluation of contemporary echocardiographic and histomorphology parameters in predicting mortality in patients with endomyocardial biopsy-proven cardiac AL amyloidosis
Authors: Koutroumpakis Efstratios , Niku Adam , Black Christopher K. , Ali Abdelrahman , Sadaf Humaira , Song Juhee , Palaskas Nicolas , Iliescu Cezar , Durand Jean-Bernard , Yusuf Syed Wamique , Lee Hans C. , Buja L. Maximilian , Deswal Anita , Banchs Jose 
Published: January 2023

IntroductionThis study examined the role of echocardiographic and cardiac histomorphology parameters in predicting mortality in patients with cardiac AL amyloidosis.MethodsPatients with endomyocardial biopsy-proven cardiac AL amyloidosis treated at MD Anderson Cancer Center between 6/2011 and 6/2020 were identified. Stored echocardiographic images and endomyocardial biopsy samples were processed for myocardial strain analysis and a detailed histomorphology characterization.ResultsOf 43 patients; 44% were women and 63% white. Median age was 65 years; 51% underwent stem cell transplantation (SCT). Thirty patients (70%) died during follow up (median follow up: 4.1 years). Lower LA strain (&lt;13.5%) and absence of SCT as a time-varying covariate were significantly associated with increased risk of death in the multivariate cox regression analysis. Higher LV mass and lower RV tricuspid annular plane systolic excursion were associated with increased odds of having ≥5% interstitial amyloid deposition on biopsy in the multivariate logistic regression analysis.ConclusionLower LA strain independently predicted mortality in our cohort, and its performance in the routine assessment of AL amyloidosis may be beneficial. Furthermore, SCT for cardiac AL amyloidosis was associated with improved OS. These findings need to be confirmed by larger studies in the era of contemporary systemic therapies.
Comparison of S-Detect and thyroid imaging reporting and data system classifications in the diagnosis of cytologically indeterminate thyroid nodules
Authors: Zhou Ling , Zheng Lin-lin , Zhang Chuan-ju , Wei Hong-fen , Xu Li-long , Zhang Mu-rui , Li Qiang , He Gao-fei , Ghamor-Amegavi Edem Prince , Li Shi-yan 
Published: January 2023

PurposeThe aim of this study was to investigate the value of S-Detect for predicting the malignant risk of cytologically indeterminate thyroid nodules (CITNs).MethodsThe preoperative prediction of 159 CITNs (Bethesda III, IV and V) were performed using S-Detect, Thyroid Imaging Reporting and Data System of American College of Radiology (ACR TI-RADS) and Chinese TI-RADS (C-TIRADS). First, Linear-by-Linear Association test and chi-square test were used to analyze the malignant risk of CITNs. McNemar’s test and receiver operating characteristic curve were used to compare the diagnostic efficacy of S-Detect and the two TI-RADS classifications for CITNs. In addition, the McNemar’s test was used to compare the diagnostic accuracy of the above three methods for different pathological types of nodules.ResultsThe maximum diameter of the benign nodules was significantly larger than that of malignant nodules [0.88(0.57-1.42) vs 0.57(0.46-0.81), P=0.002]. The risk of malignant CITNs in Bethesda system and the two TI-RADS classifications increased with grade (all P for trend&lt;0.001). In all the enrolled CITNs, the diagnostic results of S-Detect were significantly different from those of ACR TI-RADS and C-TIRADS, respectively (P=0.021 and P=0.007). The sensitivity and accuracy of S-Detect [95.9%(90.1%-98.5%) and 88.1%(81.7%-92.5%)] were higher than those of ACR TI-RADS [87.6%(80.1%-92.7%) and 81.8%(74.7%-87.3%)] (P=0.006 and P=0.021) and C-TIRADS [84.3%(76.3%-90.0%) and 78.6%(71.3%-84.5%)] (P=0.001 and P=0.001). Moreover, the negative predictive value and the area under curve value of S-Detect [82.8% (63.5%-93.5%) and 0.795%(0.724%-0.855%)] was higher than that of C-TIRADS [54.8%(38.8%-69.8%) and 0.724%(0.648%-0.792%] (P=0.024 and P=0.035). However, the specificity and positive predictive value of S-Detect were similar to those of ACR TI-RADS (P=1.000 and P=0.154) and C-TIRADS (P=1.000 and P=0.072). There was no significant difference in all the evaluated indicators between ACR TI-RADS and C-TIRADS (all P&gt;0.05). The diagnostic accuracy of S-Detect (97.4%) for papillary thyroid carcinoma (PTC) was higher than that of ACR TI-RADS (90.4%) and C-TIRADS (87.8%) (P=0.021 and P=0.003).ConclusionThe diagnostic performance of S-Detect in differentiating CITNs was similar to ACR TI-RADS and superior to C-TIRADS, especially for PTC.
Identification of microtubule-associated biomarkers in diffuse large B-cell lymphoma and prognosis prediction
Authors: Wu Wenqi , Liu Su , Tian Linyan , Li Cheng , Jiang Yanan , Wang Jinhuan , Lv Yangyang , Guo Jing , Xing Donghui , Zhai Yixin , Sun Huimeng , Li Yuhang , Zhang Luying , He Xiang , Luo Kaiping , Zhan Hongjie , Zhao Zhigang 
Published: January 2023

Background: Diffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous disease with a complicated prognosis. Even though various prognostic evaluations have been applied currently, they usually only use the clinical factors that overlook the molecular underlying DLBCL progression. Therefore, more accurate prognostic assessment needs further exploration. In the present study, we constructed a novel prognostic model based on microtubule associated genes (MAGs).Methods: A total of 33 normal controls and 1360 DLBCL samples containing gene-expression from the Gene Expression Omnibus (GEO) database were included. Subsequently, the univariate Cox, the least absolute shrinkage and selection operator (LASSO), and multivariate Cox regression analysis were used to select the best prognosis related genes into the MAGs model. To validate the model, Kaplan-Meier curve, and nomogram were analyzed.Results: A risk score model based on fourteen candidate MAGs (CCDC78, CD300LG, CTAG2, DYNLL2, MAPKAPK2, MREG, NME8, PGK2, RALBP1, SIGLEC1, SLC1A1, SLC39A12, TMEM63A, and WRAP73) was established. The K-M curve presented that the high-risk patients had a significantly inferior overall survival (OS) time compared to low-risk patients in training and validation datasets. Furthermore, knocking-out TMEM63A, a key gene belonging to the MAGs model, inhibited cell proliferation noticeably.Conclusion: The novel MAGs prognostic model has a well predictive capability, which may as a supplement for the current assessments. Furthermore, candidate TMEM63A gene has therapeutic target potentially in DLBCL.
Association of iKIR-mismatch model and donor aKIRs with better outcome in haploidentical hematopoietic stem cell transplantation for acute myeloid leukemia
Authors: Zhang Yu , Ye Chenjing , Zhu Haojie , Zhuang Youran , Chen Shaozhen , Weng Yingxi , Ren Jinhua , Luo Xiaofeng , Zheng Jing , Zheng Xiaoyun , Li Jing , Lan Lingqiong , Xie Yongxin , Han Zhongchao , Hu Jianda , Yang Ting 
Published: January 2023

ObjectivesKiller cell immunoglobulin like receptor (KIR) can trigger the alloreactivity of NK cells. However, there is no clear consensus as to their function. Here, we investigated the potential influence of KIR mismatch and KIR alleles on the outcome of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) in acute myeloid leukemia (AML) patients.MethodData from 79 AML patients treated with haplo-HSCT were retrospectively analyzed. HLA-C genotyping was determined by the PCR-rSSO method. KIR, HLA-A and HLA-B genotyping was performed by the PCR-SSP method. Cox proportional hazards model and Kaplan-Meier survival curves were used for analysis.ResultsBoth KIR ligand mismatch (KLM) group and KIR receptor-ligand mismatch (RLM) group were associated with a decreased risk in aGVHD and relapse rate (RR), and better overall survival (OS) compared to the KIR ligand matching and receptor-ligand matching groups, respectively (aGVHD: KLM: p=0.047, HR:0.235; RLM: p&lt;0.001, HR:0.129; RR: KLM: p=0.049, HR:0.686, RLM: p=0.017, HR:0.200;OS:KLM: p=0.012, HR: 0.298, RLM: p=0.021, HR:0.301). RLM was more accurate at predicting relapse and aGVHD compared with KLM (aGVHD: p=0.009; RR: p=0.039). Patients with greater number of donor activating KIRs (aKIR) had a lower incidence of aGVHD and relapse, and the benefits correlated with the increase in the number of donor aKIRs (aGVHD: p=0.019, HR:0.156; RR: p=0.037, HR:0.211). Patients with RLM and the highest number of donor aKIRs had the lowest RR, lowest incidence of aGVHD and best OS.ConclusionsBoth KLM and RLM reduced the risk of aGVHD and relapse after haplo-HSCT in AML patients, and RLM showed superiority in predicting HSCT outcome. The synergistic effects of RLM and donor aKIRs can provide a better donor selection strategy to improve haplo-HSCT outcome in AML patients.
Intravenous iron supplementation in heart failure patients induces temporary endothelial dysfunction with release of endothelial microvesicles
Authors: Mause Sebastian F. , Berger Martin , Lim Hwee Ying , Vogt Felix , Brandenburg Vincent , Stöhr Robert 
Published: January 2023

BackgroundIntravenous iron supplementation is an established therapy for patients with heart failure (HF) and concomitant iron deficiency reducing the risk of HF hospitalization. However, concerns persist regarding potential adverse vascular effects, since iron may induce oxidative stress, inflammation, and apoptosis of endothelial cells. To assess endothelial health following ferric carboxymaltose (FCM) administration, we analyzed the profile of circulating endothelial microvesicles (EMVs) and endothelial progenitor cells (EPCs) in a cohort of 23 HF patients using flow cytometry.ResultsCompared to healthy subjects, baseline levels of CD31+/CD41- EMVs were higher and EMVs featured a more apoptotic phenotype in HF patients. Following FCM administration, EMV levels showed a rapid but transient increase and displayed an altered phenotype profile with dominant augmentation of EMVs expressing inducible markers CD62E and CD54, indicating endothelial inflammatory activation and injury. Levels of circulating vasoregenerative CD45lowCD34+KDR+ EPCs were lower in HF patients and FCM application resulted in an early decrease of EPCs followed by substantial mobilization into the circulation after one week. Levels of EMVs and EPCs returned to baseline values within two and four weeks, respectively. HF patients with additional chronic kidney disease showed an elevated EMV/EPC ratio and diminished EPC mobilization, suggesting impaired vascular repair capacity. Providing a mechanistic link, in vitro experiments with cultured endothelial cells revealed that FCM dose-dependently promotes endothelial apoptosis, increases expression of adhesion molecules and CXCL12, and triggers generation of EMVs.ConclusionIntravenous iron supplementation with FCM in HF patients induces a biphasic response with initial increased release of CD62E+ and CD54+ enriched EMVs and subsequent mobilization of EPCs, indicating endothelial dysfunction upon FCM and suggesting consecutive engagement of a defense program aimed to reconstitute vascular health.