bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiology of birth defects in a national hospital-based birth defect surveillance spot in Southern Jiangsu, China, 2014–2018
Authors: Zhou Ying , Yang Di , Mao Xueqin , Zhou Hua , Wang Li 
Published: September 2023

ObjectiveAs the only hospital-based national surveillance spot of birth defects (BDs) in Changzhou city located in the economically developed eastern part of China, Changzhou Maternal and Child Health Care Hospital has encountered serious challenges in BD prevention. This study aimed to describe the epidemiology of total BDs born in the hospital from 2014 to 2018.MethodsThe data were collected from the national hospital-based birth defect surveillance system. BD prevalence was calculated by Poisson distribution. Trends of prevalence and the associations regarding information with BDs were analyzed by Poisson regression.ResultsThe reported prevalence of total BDs was 313.92 (95% confidence interval [CI]: 299.59–328.76) per 10,000 perinatal infants (PIs), while the perinatal prevalence of BD was 160.19 (95% CI: 150.00–170.89) per 10,000 PIs. A remarkable uptrend in the prevalence of BDs was noticed with a prevalence rate ratio (PRR) of 1.09 (95% CI: 1.04–1.14) and 1.13 (95% CI: 1.09–1.16), respectively. Congenital heart disease (CHD), cleft lip with or without cleft palate (CL/P), congenital malformation of the kidney (CMK), polydactyly, Down syndrome (DS), cystic hygroma, neural tube defect (NTD), and congenital talipes equinovarus (CTE) were common types of total BDs. Mothers living in the urban area (PRR = 1.67, 95% CI:1.50–1.87), male fetuses (PRR = 1.16, 95% CI: 1.05–1.28), and maternal age younger than 20 (PRR = 2.28, 95% CI: 1.60–3.25) and 25 years (PRR = 1.41, 95% CI: 1.22–1.63) or older than 35 years (PRR = 1.18, 95% CI: 1.00–1.40) were risk factors for BD occurrence.ConclusionThe reported prevalence of total BDs was nearly two times higher than the perinatal prevalence of BDs in PIs, and the ranks of total BDs and BDs in PIs were different. Mothers living in the urban area, male fetuses, and maternal ages younger than 25 or older than 35 years were risk factors for BD incidence. Thus, improving prenatal examination technology, expanding the surveillance time quantum of BDs, and keeping maternal health may be warranted.
Effect of a sustained-release formulation of β-alanine on laboratory parameters and paresthesia in recreational trained men: a randomized double-blind placebo-controlled study
Authors: Maestre-Hernández Ana Belén , Pérez-Piñero Silvia , López-Román Francisco Javier , Andreu-Caravaca Luis , Luque-Rubia Antonio J. , Ramos-Campo Domingo J. , Díaz-Silvestre María José , Ávila-Gandía Vicente 
Published: September 2023

IntroductionBeta-alanine is a non-essential amino acid that has been a focus of increasing research by its role as ergogenic aid to improve muscle performance.MethodsA randomized, double-blind and controlled trial was conducted to determine the effect of a nutritional supplement of a sustained-release formulation of β-alanine in recreational trained men. The active product was an innovative sustained-release β-alanine microgranules powder blend, administered at high doses (15 g/day) divided into 3 intakes during 30 days. There were 10 participants in the experimental group and 9 in the placebo group, with a mean age of 22.5 ± 3.3 years. Participants were testing at baseline and at the end of study.ResultsIn the β-alanine group, there were statistically increases in serum triglycerides, LDL-cholesterol, and urea nitrogen at the end of the study as compared with baseline, although there were no differences with the control group. The occurrence of paresthesia, described above all as tickling, was the majority but presented VAS score less than 3/10 in almost all subjects.DiscussionMore studies are required to evaluate the changes in blood parameters that can be caused by high intake of β-alanine during a long period of time.Clinical trial registrationClinicalTrials.gov, identifier (NCT05334121).
Oxidative stress in rat brain during experimental status epilepticus: effect of antioxidants
Authors: Fuchs Marius , Viel Christian , Lehto Alina , Lau Helene , Klein Jochen 
Published: September 2023

Antioxidants have been proposed as a treatment for diseases of the central nervous system. However, few studies actually studied their effects in the brain. To test central actions of antioxidants, we used the lithium–pilocarpine (Li-Pilo) model of status epilepticus (SE) in the rat in which seizures are accompanied by significant oxidative stress. We used in vivo microdialysis to determine isoprostane levels during SE in real time and brain homogenates for other measures of oxidative stress. Six different antioxidants were tested in acute and preventive experiments (vitamin C, vitamin E, ebselen, resveratrol, n-tert-butyl-α-phenylnitrone and coenzyme Q10). None of the antioxidants had an effect when given acutely during SE. In contrast, when antioxidants were given for 3 days prior to seizure induction, vitamins C and E reduced isoprostane formation by 58% and 65%, respectively. Pretreatment with the other antioxidants was ineffective. In brain homogenates prepared after 90 min of seizures, SE decreased the ratio of reduced vs. oxidized glutathione (GSH/GSSG ratio) from 60.8 to 7.50 and caused a twofold increase of 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels and protein carbonyls. Pretreatment with vitamin C or vitamin E mitigated these effects and increased the GSH/GSSG ratio to 23.9 and 28.3, respectively. Again, the other antioxidants were not effective. We conclude that preventive treatment with vitamin C or vitamin E ameliorates seizure-induced oxidative damage in the brain. Several well-studied antioxidants were inactive, possibly due to limited brain permeability or a lack of chain-breaking antioxidant activity in hydrophilic compounds.
Transforming healthcare documentation: harnessing the potential of AI to generate discharge summaries
Authors: Clough Reece Alexander James , Sparkes William Anthony , Clough Oliver Thomas , Sykes Joshua Thomas , Steventon Alexander Thomas , King Kate 
Published: September 2023

BackgroundHospital discharge summaries play an essential role in informing GPs of recent admissions to ensure excellent continuity of care and prevent adverse events; however, they are notoriously poorly written, time-consuming, and can result in delayed discharge.AimTo evaluate the potential of artificial intelligence (AI) to produce high-quality discharge summaries equivalent to the level of a doctor who has completed the UK Foundation Programme.Design & settingFeasibility study using 25 mock patient vignettes.MethodTwenty-five mock patient vignettes were written by the authors. Five junior doctors wrote discharge summaries from the case vignettes (five each). The same case vignettes were input into ChatGPT. In total, 50 discharge summaries were generated; 25 by Al and 25 by junior doctors. Quality and suitability were determined through both independent GP evaluators and adherence to a minimum dataset.ResultsOf the 25 AI-written discharge summaries 100% were deemed by GPs to be of an acceptable quality compared with 92% of the junior doctor summaries. They both showed a mean compliance of 97% with the minimum dataset. In addition, the ability of GPs to determine if the summary was written by ChatGPT was poor, with only a 60% accuracy of detection. Similarly, when run through an AI-detection tool all were recognised as being very unlikely to be written by AI.ConclusionAI has proven to produce discharge summaries of equivalent quality to a junior doctor who has completed the UK Foundation Programme; however, larger studies with real-world patient data with NHS-approved AI tools will need to be conducted.
Fatores associados à qualidade de vida de pessoas com Espinha Bífida
Authors: Lucio Maria Clara Fagundes , Sambe Angélica Yumi , Valenciano Paola Janeiro , Siqueira Emanuely Andreoli , Pellizzari Camila Costa de Araujo , Da Silva Joyce Karla Machado 
Published: September 2023

Introdução. Espinha bífida é um distúrbio neurológico caracterizado pelo desenvolvimento incompleto do tubo neural, sendo a mielomeningocele seu tipo mais comum e grave, no qual possui fatores que impactam em seu estado de saúde, e consequentemente na qualidade de vida. Objetivo. Verificar e reunir fatores que impactam na qualidade de vida de indivíduos com espinha bífida e os principais instrumentos de avaliação utilizados. Método. Trata-se de uma revisão de literatura, com buscas bibliográficas nas bases Science Direct, Lilacs, Pubmed, Cochrane e Scielo, no período de janeiro de 2022 e atualizada em dezembro de 2022. Resultados. Foram incluídos 12 estudos realizados entre 2005 a 2019. O instrumento de avaliação Child Health Questionnaire foi encontrado como o questionário mais utilizado entre os artigos. E os desfechos encontrados que mais impactam na qualidade de vida de indivíduos com espinha bífida foi a incontinência intestinal e urinária. Conclusão. Espinha bífida é uma condição complexa que leva a comprometimento de diferentes componentes do corpo, podendo levar a limitações em atividades e restrições na participação. A presença de incontinência urinária e fecal são os fatores que mostraram impactar de forma negativa a qualidade de vida nessa população, havendo necessidade de maior atenção em ações de educação e manejo. Além disso, definir um instrumento de avaliação e identificar os desfechos em saúde que impactam é essencial para o trabalho multidisciplinar e o tratamento.
THE COMPARISON ANALYSIS OF INDONESIAN COMPANY'S FINANCIAL PERFORMANCE BEFORE AND DURING THE COVID-19 PANDEMIC
Authors: Fujianti Lailah , Mira Munira  , Sri Lestari Tindaon  
Published: September 2023

This study aims to analyze differences in financial performance before and during the covid-19 pandemic in manufacturing companies listed on the Indonesia Stock Exchange in 2019 - 2020 from liquidity, leverage and profitability. The research sample was 138 companies which were selected based on the purposive sampling method. The paired sample t test method was used for data analysis. The results showed that there was no significant difference in the financial performance of manufacturing companies in terms of liquidity and leverage before and during the covid 19 pandemic. In terms of profitability, there was a significant difference, namely the average decrease in profitability.
Keywords: liquidity, leverage, profitability, manufacture
THE INFLUENCE OF GREEN INTELLECTUAL CAPITAL, DIVIDEND POLICY, PROFITABILITY RATIO AND ACTIVITY RATIO ON COMPANY VALUE
Authors: Astuti Tri , Ambarwati Sri , Wibowo Frides Dyah 
Published: September 2023

Abstractk
This study aims to determine the effect of green intellectual capital, dividend policy, profitability ratios and activity ratios on firm value. This study takes a sample of companies listed on the Indonesia Stock Exchange which are included in the Sri-KEHATI Index list for the 2016-2020 period. The sample in this study a sample of 9 companies with a total of 45 observations of observation data for 5 years. A total of 5 outlier data have been removed from the analysis so that the total observations are 40 observational data. The data analysis method used is panel data regression with the help of the Eviews 9 program. The results show that partially green intellectual capital, dividend payout ratio and return on equity have no effect on firm value.
THE EFFECT OF DIGITAL FINANCIAL, CREDIT RISK, OVERHEAD COST, AND NON-INTEREST INCOME ON BANK STABILITY
Authors: Idawati Wiwi , Syafputri Shania Anasthasia 
Published: September 2023

ABSTRACT

This research aims to find out and analyze the influence of digital finance, credit risk, overhead cost, and non-interest income on the stability of banks from the banking industry included in conventional banks listed on the Indonesia Stock Exchange (IDX) in the period 2016 to 2020. Sample selection uses the purposive sampling method. The number of samples used in this study amounted to 40 Conventional Banks registered IDX. The independent variable consists of Digital Finance measured using dummy variables, namely 1 if the bank launches a mobile banking application and 0 if vice versa, Credit Risk measured using Non Performing Loan (NPL), Overhead Cost measured using overhead expense ratio divided by total assets, and Non-Interest Income as measured by non-interest income ratio divided by total operating income. Furthermore, the study's dependent variable is Bank Stability as measured using Z-scores. This study compares two research results based on the COVID-19 Pandemic period, namely research I before COVID-19 with 2016 to 2019 and research II when COVID19 with only 2020. The results showed that Digital Finance had a positive effect on both studies, Credit Risk had a negative effect on both studies, Overhead Cost had no effect, and Non-Interest Income had no effect on the study period I and negatively on the study period II.
Keywords: Digital Finance, Mobile Banking, Credit Risk, NPL, Overhead Cost, Non-Interest Income
APPROACHES TO THE DEVELOPMENT OF A LIGHT FIRE MODULE ROCKET LAUNCHERS SYSTEM ON WHEELED (TRACKED) CHASSIS
Authors: Kapliuk O. , Kirdeі L. , Kaletnik S. , Manzhara O. 
Published: September 2023

Today, in the conditions of russia's open armed aggression against Ukraine and the intense multi-faceted struggle against it - armed, informational, economic, the Armed Forces of Ukraine have to create combat-ready groups of troops (forces) that must be able to ensure the fulfillment of the tasks assigned to them at a given level. Based on the experience of conducting hostilities starting from February 24, 2022, it becomes clear that one of the important components of the effective conduct of hostilities by troops (forces) is the timely and reasonable use of missile forces and artillery.
One of the common effective and promising fire means of the field artillery of the ground forces is the reactive system of volley fire. Shelling from such systems not only destroys manpower and equipment, but also creates a powerful psychological impact on the enemy's personnel. So, despite the appearance of new modern means of destruction, rocket launcher systems will continue to play the role of a strong argument on the battlefield for a long time, and designers will continue to work on their further improvement.
Today, systems of volley fire represent combat platforms that are widely used by the Ground Forces in conducting all forms and types of combat operations. Development of new, improvement of existing systems of volley fire, improvement of their combat effectiveness is an important scientific and technical task.
The most important advantages of reactive systems of volley fire are the surprise of the attack and the high density of fire, which is carried out in a very short time on site targets with a high degree of damage, both offensively and defensively, in any weather, both day and night.
In a number of modern local conflicts, aviation units for unguided air missiles of the S-5 and S-8 types installed on various self-propelled chassis were used as improvised systems of volley fire.
But the lack of developed special sights and sufficient stabilization of unguided aircraft missiles during launch gives low accuracy. Therefore, the issue of increasing the accuracy and efficiency of the use of unguided air missiles from a wheeled (tracked) chassis requires further development.
The article substantiates the need to create a light fire module for the use of unguided aircraft missiles from wheeled (tracked) chassis instead of using standard aviation units of unguided missile weapons, proposed solutions to improve the accuracy and efficiency of application.
METHOD OF CALCULATING THE UNSTATIONARY TEMPERATURE FIELD PARTS OF THE SPHERICAL FORM OF THE STRUCTURE FLIGHT APPARATUS OF UNMANNED AVIATION COMPLEXES
Authors: Orlov S. , Chervotoka О. , Herashchenko M. 
Published: September 2023

The design of unmanned aircraft vehicles during operation is exposed to significant temperature effects, which causes changes in the dielectric characteristics of radio technical elements and can lead to failures of on-board radio electronic equipment, as a result of which the task of determining the amount of temperature change in the compartments where the radio electronic equipment is located is performed. At the same time, some external elements of the aircraft vehicle can have complex structures with shapes close to spherical and different thicknesses in each cross-sectional structure.
There is a need to develop a method for calculating the non-stationary temperature field with the purpose of finding out the real conditions in which all the elements of the aircraft structure work, which would help to determine how the temperature of the structure changes during any flight. At the same time, it is necessary to take into account the three dimensions of temperature gradients on spherical parts of structures of various shapes, namely nose part, rounded wing and others. In them, as a rule, each cross-section of the wall has its own thickness and, according to each cross-section, the temperature distribution along the thickness of the wall will correspond, that is, it is necessary to ensure the redistribution of temperature along the structural element, the calculation of which month. In addition, it is necessary to note that the wall of the aircraft can be multi-layered and the properties of its material can change along with the change in temperature. Considering the fact that it is impossible to take into account all the listed features by analytical methods, when choosing a calculation method, it will be advisable to stop at numerical methods.
One of the most well-known numerical methods is the finite difference method with an implicit calculation scheme, which has an indisputable advantage for modeling - absolute stability with sufficient changes in time and coordinate steps. We will use the level of thermal conductivity in spherical coordinates in order to increase the accuracy of the calculation, for which solution, after finding out the boundary conditions, we will perform a one-dimensional calculation of the temperature by thickness in each mesh section of the structure, and also perform a calculation of the two-dimensional "heat flow" along the solid between the points, that are located on the same thickness, but have a temperature difference. Thus, when calculating the temperature field, the sphericity and multi-lay redness of the structural elements is taken into account, and the property of the material of the aircraft structure changes depending on the temperature.
El fansubbing en contraste con la traducción profesional
Authors: De los santos Contreras Alondra 
Published: September 2023

El presente estudio cualitativo tiene como objetivo analizar de forma contrastada el fansubbing y la traducción profesional, sus connotaciones en las técnicas y herramientas, su conocimiento y aplicación en los aspectos traductológicos y culturales, así como sus similitudes y diferencias, a través de tablas de observación en la que se comparan los tratados de ambos tipos de traducción. El fansubbing, es la práctica de la traducción informal de contenidos hecha por los fans, el nombre de dicha técnica proviene de fan admirador y subbing subtitulado o traslación. En un mundo globalizado la aceptación de la traducción de diferentes productos multimedia ha cobrado popularidad, lamentablemente su disponibilidad en diferentes idiomas es poco e incluso nulo en algunos casos, de ahí la importancia del fansubbing para la traducción profesional. Como resultado, se revela que el fansubbing no representa una amenaza para la traducción profesional sino un impulso para mejorar el traslado de productos audiovisuales.
Propuesta de Modelo Curricular para el Desarrollo y Fortalecimiento de las Competencias Socio Emocionales desde las diferentes áreas del Conocimiento en los Centros Educativos Públicos de Manizales
Authors: Duque Cano Fredie , García Castro Ligia Inés 
Published: September 2023

Los inicios del milenio, cargados de cambios, plantean la necesidad de la re organización de la educación. Al respecto Harari (2018) pregunta “¿Cómo prepararnos y preparar a nuestros hijos para un mundo de transformaciones sin precedentes y de incertidumbres radicales?”. Sin embargo, en la mayoría de los sistemas educativos Latinoamericanos, las transformaciones no se vislumbran; los currículos se inclinan preponderantemente hacia el ámbito intelectual, dejando en un segundo plano lo socio emocional. La ausencia de la inteligencia emocional, ha generado problemas como: agresividad, drogadicción, suicidio, y en el ámbito educativo elevados índices de fracaso y abandono escolar. Todo esto, muestra la necesidad de integrar las competencias emocionales, a los procesos curriculares. Así lo ratifica el Dr. Dirk Voin Damme que expreso: “Las competencias socio emocionales deben ser tratadas e integradas en los sistemas educativos modernos en igualdad de condiciones con las competencias cognitivas, (Organización de las Naciones Unidas para la Educación, la Ciencia y la Cultura [UNESCO], 2018). Por tanto, se ha esbozado la siguiente propuesta que tiene como objetivo diseñar un modelo curricular para la enseñanza y el fortalecimiento de las competencias socio emocionales desde las diferentes áreas del conocimiento. La investigación con un enfoque cualitativo, un diseño de investigación acción y un desarrollo metodológico basado en fases cíclicas o espiral que desencadenan en tres perspectivas fundamentales: la primera una Visión técnica-científica que comprende Ciclos repetitivos de análisis que conducen a conceptualizaciones y redefiniciones del problema; la segunda una Visión deliberativa en donde se realiza la Interpretación de resultados y finalmente una visión emancipadora en donde se generan los cambios.