bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial light impairs local attraction to females in male glow-worms
Authors: Moubarak Estelle M. , David Fernandes A. Sofia , Stewart Alan J. A. , Niven Jeremy E. 
Published: June 2023

ABSTRACTThe negative effects of artificial lighting at night (ALAN) on insects are increasingly recognised and have been postulated as one possible cause of declines in insect populations. Yet, the behavioural mechanisms underpinning ALAN effects on insects remain unclear. ALAN interferes with the bioluminescent signal female glow-worms use to attract males, disrupting reproduction. To determine the behavioural mechanisms that underpin this effect of ALAN, we quantified the effect of white illumination on males' ability to reach a female-mimicking LED within a Y-maze. We show that as the intensity of illumination increases, the proportion of males reaching the female-mimicking LED declines. Brighter illumination also increases the time taken by males to reach the female-mimicking LED. This is a consequence of males spending more time: (i) in the central arm of the Y-maze; and (ii) with their head retracted beneath their head shield. These effects reverse rapidly when illumination is removed, suggesting that male glow-worms are averse to white light. Our results show that ALAN not only prevents male glow-worms from reaching females, but also increases the time they take to reach females and the time they spend avoiding exposure to light. This demonstrates that the impacts of ALAN on male glow-worms extend beyond those previously observed in field experiments, and raises the possibility that ALAN has similar behavioural impacts on other insect species that remain undetected in field experiments.
Personalized Healthcare Outcome Analysis of Cardiovascular Surgical Procedures
Authors: Wang Guihua , Li Jun , Hopp Wallace J. 
Published: June 2023

Problem definition: This study addresses three important questions concerning personalized healthcare: (1) Are outcome differences between hospitals heterogeneous across patients with different features? (2) If they are, how do the best quality hospitals identified using patient-centric information differ from those identified using population-average information? (3) How much will hospitals’ pay-for-performance reimbursements change if their performance is measured based on patient-centric information? Methodology/results: Using patient-level data from 35 hospitals for six cardiovascular surgeries in New York State, we identify patient groups that exhibit significant differences in outcomes with a recently developed instrumental variable tree approach. We find outcome differences between hospitals are heterogeneous not only across procedure types, but also along other dimensions such as patient age and comorbidities. For around 80% of patients, the best quality hospitals indicated by patient-centric information are different from those indicated as best according to population-average information. Managerial implications: We compare potential outcomes when patients are treated at the best quality hospitals based on the two types of information and find complications could be reduced by using patient-centric information instead of population-average information. We also use our model to illustrate how patient-centric information can enhance pay-for-performance programs offered by payers and guide hospitals in targeting quality-improvement efforts.History: This paper was a finalist in the 2017 MSOM Student Paper Competition.Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.1227 .
Emotional intelligence and conflict resolution styles among nurse managers: a cross-sectional study
Authors: Assi Mohammad Dar , Eshah Nidal F 
Published: June 2023

Background/AimsEmotional intelligence may help nurse managers to deal with conflicts. However, the relationship between emotional intelligence and conflict resolution is still not clearly understood. This study aimed to explore nurse managers' emotional intelligence levels and conflict resolution styles, and to identify any associations between these factors.MethodsA cross-sectional study design was used, with a convenience sample of 197 nurse managers recruited from five public and two university hospitals. Data were collected on emotional intelligence and conflict resolution using two specialised self-reported scale-based questionnaires. The Statistical Package for Social Sciences (version 25) was used to analyse data, with P<0.05 indicating statistical significance.ResultsThe nurse mangers' average emotional intelligence scores ranged from 80–139 and 40% had low levels of work-related emotional intelligence. The integrating style was the most commonly used approach to conflict resolution, while the avoiding style was the least used. Higher levels of emotional intelligence were significantly associated with integrating, obliging and compromising styles, and were able to predict the use of integrating and compromising styles of conflict resolution.ConclusionsNurse managers with higher levels of emotional intelligence are more likely to use the integrating and compromising styles of conflict resolution. Training programmes aiming to improve managers' conflict resolution skills should focus on assessing and increasing emotional intelligence.
Scan-free time-of-flight-based three-dimensional imaging through a scattering layer
Authors: Deng Rujia , Jin Xin , Du Dongyu , Li Zhiheng 
Published: June 2023

Reconstructing an object’s three-dimensional shape behind a scattering layer with a single exposure is of great significance in real-life applications. However, due to the little information captured by a single exposure while strongly perturbed by the scattering layer and encoded by free-space propagation, existing methods cannot achieve scan-free three-dimensional reconstruction through the scattering layer in macroscopic scenarios using a short acquisition time of seconds. In this paper, we proposed a scan-free time-of-flight-based three-dimensional reconstruction method based on explicitly modeling and inverting the time-of-flight-based scattering light propagation in a non-confocal imaging system. The non-confocal time-of-flight-based scattering imaging model is developed to map the three-dimensional object shape information to the time-resolved measurements, by encoding the three-dimensional object shape into the free-space propagation result and then convolving with the scattering blur kernel derived from the diffusion equation. To solve the inverse problem, a three-dimensional shape reconstruction algorithm consisting of the deconvolution and diffractive wave propagation is developed to invert the effects caused by the scattering diffusion and the free-space propagation, which reshapes the temporal and spatial distribution of scattered signal photons and recovers the object shape information. Experiments on a real scattering imaging system are conducted to demonstrate the effectiveness of the proposed method. The single exposure used in the experiment only takes 3.5 s, which is more than 200 times faster than confocal scanning methods. Experimental results show that the proposed method outperforms existing methods in terms of three-dimensional reconstruction accuracy and imaging limit subjectively and objectively. Even though the signal photons captured by a single exposure are too highly scattered and attenuated to present any valid information in time gating, the proposed method can reconstruct three-dimensional objects located behind the scattering layer of 9.6 transport mean free paths (TMFPs), corresponding to the round-trip scattering length of 19.2 TMFPs.
Migraine and risk of premature myocardial infarction and stroke among men and women: A Danish population-based cohort study
Authors: Hvitfeldt Fuglsang Cecilia , Pedersen Lars , Schmidt Morten , Vandenbroucke Jan P. , Bøtker Hans Erik , Sørensen Henrik Toft 
Published: June 2023

Background
Migraine carries risk of myocardial infarction (MI) and stroke. The risk of premature MI (i.e., among young adults) and stroke differs between men and women; previous studies indicate that migraine is mainly associated with an increased risk of stroke among young women. The aim of this study was to examine impact of migraine on the risk of premature (age ≤60 years) MI and ischemic/hemorrhagic stroke among men and women.

Methods and findings
Using Danish medical registries, we conducted a nationwide population-based cohort study (1996 to 2018). Redeemed prescriptions for migraine-specific medication were used to identify women with migraine (n = 179,680) and men with migraine (n = 40,757). These individuals were matched on sex, index year, and birth year 1:5 with a random sample of the general population who did not use migraine-specific medication. All individuals were required to be between 18 and 60 years old. Median age was 41.5 years for women and 40.3 years for men.
The main outcome measures to assess impact of migraine were absolute risk differences (RDs) and hazard ratios (HRs) with 95% confidence intervals (CIs) of premature MI, ischemic, and hemorrhagic stroke, comparing individuals with migraine to migraine-free individuals of the same sex. HRs were adjusted for age, index year, and comorbidities. The RD of premature MI for those with migraine versus no migraine was 0.3% (95% CI [0.2%, 0.4%]; p < 0.001) for women and 0.3% (95% CI [−0.1%, 0.6%]; p = 0.061) for men. The adjusted HR was 1.22 (95% CI [1.14, 1.31]; p < 0.001) for women and 1.07 (95% CI [0.97, 1.17]; p = 0.164) for men. The RD of premature ischemic stroke for migraine versus no migraine was 0.3% (95% CI [0.2%, 0.4%]; p < 0.001) for women and 0.5% (95% CI [0.1%, 0.8%]; p < 0.001) for men. The adjusted HR was 1.21 (95% CI [1.13, 1.30]; p < 0.001) for women and 1.23 (95% CI [1.10, 1.38]; p < 0.001) for men. The RD of premature hemorrhagic stroke for migraine versus no migraine was 0.1% (95% CI [0.0%, 0.2%]; p = 0.011) for women and −0.1% (95% CI [−0.3%, 0.0%]; p = 0.176) for men. The adjusted HR was 1.13 (95% CI [1.02, 1.24]; p = 0.014) for women and 0.85 (95% CI [0.69, 1.05]; p = 0.131) for men.
The main limitation of this study was the risk of misclassification of migraine, which could lead to underestimation of the impact of migraine on each outcome.

Conclusions
In this study, we observed that migraine was associated with similarly increased risk of premature ischemic stroke among men and women. For premature MI and hemorrhagic stroke, there may be an increased risk associated with migraine only among women.
The Worcester Herbal Glossary: Edition and Commentary
Authors: Cataldi Claudio 
Published: June 2023

Abstract
This study offers the first full edition of a late thirteenth-century herbal glossary preserved in Worcester, Cathedral Library, F 157, as well as a preliminary commentary of textual problems and analogues. This glossary (henceforth: Worcester Herbal Glossary) originally included around 130 Latin plant names with English equivalents; a few entries are lost today because of a lacuna in the manuscript. So far, only a partial – and at times inaccurate – edition of the glossary appeared in Floyer and Hamilton (1906: 184–185). Since then, this lexicographic collection of plant names has been almost wholly ignored by scholars. Remarkably, the Worcester Herbal Glossary seems to originate from a substantial batch of entries from the chapter on the names of herbs in Ælfric’s Glossary. This batch was expanded by means of other material which must have circulated in the Early Middle English period. This additional material parallels entries found in other botanical glossaries of the period – such as that preserved in London, British Library, Harley 978 – and, above all, finds striking analogues in the Middle English recension of the Salernitan medico-botanical glossary known as Alphita (Mowat 1887).
Thermal vibration of perforated nanobeams with deformable boundary conditions via nonlocal strain gradient theory
Authors: Kafkas Uğur , Uzun Büşra , Yaylı Mustafa Özgür , Güçlü Gökhan 
Published: June 2023

Abstract
Due to nonlocal and strain gradient effects with rigid and deformable boundary conditions, the thermal vibration behavior of perforated nanobeams resting on a Winkler elastic foundation (WEF) is examined in this paper. The Stokes transformation and Fourier series have been used to achieve this goal and to determine the thermal vibration behavior under various boundary conditions, including deformable and non-deformable ones. The perforated nanobeams’ boundary conditions are considered deformable, and the nonlocal strain gradient theory accounts for the size dependency. The problem is modeled as an eigenvalue problem. The effect of parameters such as the number of holes, elastic foundation, nonlocal and strain gradient, deformable boundaries and size on the solution is considered. The effects of various parameters, such as the length of the perforated beam, number of holes, filling ratio, thermal effect parameter, small-scale parameters and foundation parameter, on the thermal vibration behavior of the perforated nanobeam, are then illustrated using a set of numerical examples. As a result of the analysis, it was determined that the vibration frequency of the nanobeam was most affected by the changes in the dimensionless WEF parameter in the first mode and the changes in the internal length parameter when all modes were considered.
Dicer structure and function: conserved and evolving features
Authors: Zapletal David , Kubicek Karel , Svoboda Petr , Stefl Richard 
Published: June 2023

AbstractRNase III Dicer produces small RNAs guiding sequence‐specific regulations, with important biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference (RNAi) and microRNA (miRNA) pathways, which employ distinct types of small RNAs. Small interfering RNAs (siRNAs) for RNAi are produced by Dicer from long double‐stranded RNA (dsRNA) as a pool of different small RNAs. In contrast, miRNAs have specific sequences because they are precisely cleaved out from small hairpin precursors. Some Dicer homologs efficiently generate both, siRNAs and miRNAs, while others are adapted for biogenesis of one small RNA type. Here, we review the wealth of recent structural analyses of animal and plant Dicers, which have revealed how different domains and their adaptations contribute to substrate recognition and cleavage in different organisms and pathways. These data imply that siRNA generation was Dicer's ancestral role and that miRNA biogenesis relies on derived features. While the key element of functional divergence is a RIG‐I‐like helicase domain, Dicer‐mediated small RNA biogenesis also documents the impressive functional versatility of the dsRNA‐binding domain.
Nicotine exposure disrupts placental development via the Notch signaling pathway
Authors: Sun Qiao-Ran , Wu Dan-Ya , Zhang Jing-Jing , Wu Lin-Hui , Zhang Xia , Zhou Jilong , Miao Yi-Liang 
Published: June 2023

In brief
Normal gene expression during early embryonic development and in the placenta is crucial for a successful pregnancy. Nicotine can disrupt normal gene expression during development, leading to abnormal embryonic and placental development.

Abstract
Nicotine is a common indoor air pollutant that is present in cigarette fumes. Due to its lipophilic nature, nicotine can rapidly transport through membrane barriers and spread throughout the body, which can lead to the development of diseases. However, the impact of nicotine exposure during early embryonic development on subsequent development remains elusive. In this study, we found that nicotine significantly elevated reactive oxygen species, DNA damage and cell apoptosis levels with the decrease of blastocyst formation during early embryonic development. More importantly, nicotine exposure during early embryonic development increased placental weight and disrupted placental structure. In molecular level, we also observed that nicotine exposure could specifically cause the hypermethylation of Phlda2 promoter (a maternally expressed imprinted gene associated with placental development) and reduce the mRNA expression of Phlda2. By RNA sequencing analysis, we demonstrated that nicotine exposure affected the gene expression and excessive activation of the Notch signaling pathway thereby affecting placental development. Blocking the Notch signaling pathway by DAPT treatment could recover abnormal placental weight and structure induced by nicotine exposure. Taken together, this study indicates that nicotine causes the declining quality of early embryos and leads to placental abnormalities related to over-activation of the Notch signaling pathway.
Co-seismic displacements of the 1994 Northridge, California, earthquake
Authors: Hudnut K. W. , Shen Z. , Murray M. , McClusky S. , King R. , Herring T. , Hager B. , Feng Y. , Fang P. , Donnellan A. , Bock Y. 
Published: June 2023

AbstractThe 17 January 1994 Northridge, California, earthquake significantly deformed the Earth's crust in the epicentral region. Displacements of 66 survey stations determined from Global Positioning System (GPS) observations collected before and after the earthquake show that individual stations were uplifted by up to 417 ± 5 mm and displaced horizontally by up to 216 ± 3 mm. Using these displacements, we estimate parameters of a uniform-slip model. Fault geometry and slip are estimated independent of seismological information, using Monte Carlo optimization techniques that minimize the model residuals. The plane that best fits the geodetic data lies 1 to 2 km above the plane indicated by aftershock seismicity. Modeling for distributed slip on a coplanar, yet larger model fault indicates that a high-slip patch occurred up-dip and northwest of the mainshock hypocenter and that less than 1 m of slip occurred in the uppermost 5 km of the crust. This finding is consistent with the lack of clear surface rupture and with the notion that the intersection with the fault that ruptured in 1971 formed the up-dip terminus of slip in the Northridge earthquake. Displacements predicted by either of these simple models explain most of the variance in the data within 50 km of the epicenter. On average, however, the scatter of the residuals is twice the data uncertainties, and in some areas, there is significant systematic misfit to either model. The co-seismic contributions of aftershocks are insufficient to explain this mismatch, indicating that the source geometry is more complicated than a single rectangular plane.
Remote Monitoring of the QT Interval During Polychemotherapy
Authors: Fashafsha Z. Z.A. , Chomakhidze P. Sh. , Mesitskaya D. F. , Novikova A. I. , Potemkina N. A. , Suvorov A. Yu. , Tyukanova E. S. , Fatyanova A. S. , Agakina Yu. S. , Sekacheva M. I. , Poddubskaya E. V. , Kopylov Ph. Yu. 
Published: June 2023

Aim To evaluate the incidence of prolonged corrected QT interval (QTc) by remote single-channel electrocardiogram (ECG) monitoring in primary oncological patients with elective polychemotherapy (PCT).Material and methods This study included 49 oncological patients with elective PCT. A single-channel portable CardioQVARK electrocardiograph was used to record single-channel, one-lead ECG between the first and second courses of PCT.Results Analysis of QTc interval detected a prolonged QTc interval >500 msec in 8.2 % of cases, prolonged QTc >480 msec in 18.3 % f cases, and prolonged QTc interval >60 msec compared to baseline in 12.2 % of cases.Conclusion Remote recording of single-channel ECG using a portable electrocardiograph is an effective method for recording and detecting various forms of heart rhythm disorders.
Comparison of Two Different Intervals of Misoprostol Administration in Second Trimester Abortions
Authors: Gupta Anjali , Gautam Sarika , Chanana Shelly , Sangwan Neetu , Singhal Savita Rani , Anand Smriti , Dahiya Sonia 
Published: June 2023

Objective: Comparison of two different intervals of misoprostol administration after mifepristone in second trimester abortions.
Materials and methods: This 12-month prospective study was conducted at a tertiary care facility. Only pregnancies with congenital deformity or sterilisation failure were included in the study's recruitment of 100 women who visited the hospital for a second trimester abortion between 12 and 20 weeks; cases with scarred uteri were omitted. In a systematic random selection of 50 women in each group, the administration of 200 mg of mifepristone orally was followed by two distinct intervals of intravaginal misoprostol administration at 24- and 48-hour intervals. After 24 hours, group A women received intravaginal 400 mcg misoprostol three hourly, up to a maximum of five doses, while group B received the same doses after 48 hours. Induction abortion interval noted on various parameters and paired t test and chi square test applied.
Results: The mean IAI following misoprostol administration was 8.14 2±.03 hours in group A and 7.71 ±2.56 hours in group B. This difference was statistically insignificant. Average misoprostol doses for group A were 1.68±0.71 and for the group, B were 1.68±0.84; both doses were found to be statistically insignificant when used to induce abortion. All women aborted successfully in each group. There was no significant difference in side effects in both groups.
Conclusion: Based on the results it was observed that shorter interval between mifepristone and misoprostol i.e., 24 hours can be chosen to decrease the hospital stay as there was no significant difference was seen after intravaginal misoprostol in terms of induction abortion interval, number of doses and side effects.
Effect of Insulin Therapy on Traumatic Patients: A Scoping Review
Authors: Harorani Mehdi , Masmouei Behnam , Zarei Ali , Jahangiri Fereidoun , Bazrafshan Mohammad Rafi , Karimi Zahra , Akbari Mehran 
Published: June 2023

Background: Trauma is one of the most important causes of death in. Therefore, proper management and treatment of these patients can be very beneficial. Therefore, the aim of this literature was to investigate the extent, scope and nature of researches on the effect of insulin therapy on the treatment efficacy of traumatic patients.Methods: This study is a scoping review of research that was conducted by searching in Scopus, PubMed, Embase and ScienceDirect databases with keywords related to insulin therapy and trauma. In this study, all reports with human and animals as well as cohort and clinical trial studies were reviewed.Results: Of the 4365 studies, 73 studies met the inclusion criteria and were evaluated, most studies examining the effect of insulin on traumatic brain injury and immune system and the fewest were in trunk trauma patients, especially chest trauma. The findings of this study showed the effect of insulin therapy on decreasing levels of IL-6, IL-8, IL-10 and TNF-α thus decreasing the inflammatory response in trauma patients. Insulin therapy can reduce the risk of infection in patients with trauma and burns thereby reducing the number of days spent in intensive care units and dependence on ventilation. Conclusion: Insulin therapy can be useful in treating trauma patients but increases the rate of hypoglycemic episodes that require careful monitoring of patients’ blood glucose which can have a negative impact on treatment outcomes.