bluuebunny/crossref_metadata_2025_split huggingface dataset:
The mechanisms of plugging due to scaling and fines migration and the change characteristics of relative permeability curve after CO2 flooding
Authors: liu yiwen , fu meilong , wang changquan , xu shijing , meng fankun , shen yanlai 
Published: April 2023

Abstract
Since the exploitation of Block 8 of Jinglou Oilfield, owing to the constant increase in water influx, coupled with low system pressure (8.9 MPa), the water influx affected by the water injection wells every year has been near 2×104 m3, the formation pressure has exhibited a year-by-year ascending trend, and the contradiction of water injection well plugging removal has been increasingly prominent. In view of these problems, the following experiments were carried out: the experiment on scaling laws of inorganic scale under the interactions of CO2 at different concentrations with formation water, the experiment on laws of plugging due to fines migration caused by CO2 flooding, the experiment on mechanisms of plugging by organic scale after CO2 flooding and on plugging removal, and the evaluation experiment on oil-water relative permeability curve after CO2 flooding. The results show that there is a CaCO3 scaling trend existing between CO2 and formation water in the flooding process under reservoir conditions. After CO2 flooding, there is plugging effect due to conglomeration of inorganic scale, organic scale and fines, causing the seepage capacity of the reservoir to become poor, with a loss of core permeability of 69.6%. After the reservoir is washed with toluene and absolute alcohol, its seepage capacity is recovered slightly, with a recovery of core permeability of 42.2%. It can be discerned from the shape of the relative permeability curves that the change characteristics of two-phase relative permeability curves before and after CO2 flooding exhibit rightward shift for all cores with different permeability values, with the bound water saturation increasing (more than 35%), indicating that the CO2-water-rock karstification caused by CO2 flooding enlarges the pore space and seepage channels, enhancing the water injectivity. This study is of great theoretical and practical significance for plugging removal and augmented injection in water injection wells.
Clostridioides difficile infection in frail older patients, quality in treatment and care: the CLODIFRAIL study protocol for a multicentre randomised controlled trial
Authors: Rubak Tone , Veilbæk Hanne , Gregersen Merete , Asferg Malene , Barat Ishay , Johnsen Joanna Secher , Riis Mikael Groth , Rosenbæk Jeppe , Ørum Marianne , Vinding Rita Stockholm , Sørensen Carl Aksel Kragh , Steves Claire J , Baunwall Simon Mark Dahl , Hvas Christian Lodberg , Damsgaard Else Marie Skjøde 
Published: April 2023

Abstract

Background:Clostridioides difficileinfection (CDI) is complex and associated with adverse clinical outcomes in older patients, including increased mortality rates. Effective transition of care for patients with CDI is critical to improve survival and health outcomes and to reduce recurrence rates. The aim of this study is to investigate the effects of a geriatric tailored intervention for older patients with CDI on patient survival, compared with older patients with CDI who receive usual care.Methods: This is a quality improvement study, comparing two organisational pathways. We include 216 patients aged 70 years or more and diagnosed with CDI. Patients with a positiveClostridioides difficiletoxin PCR test are randomised 1:1 to either 1) a geriatric tailored assessment and intervention (the CLODIFRAIL intervention) or 2) usual care at the treating physician’s discretion. The intervention consists of three main parts: 1) a clinical geriatric assessment; 2) a clinical evaluation of indication for and treatment with faecal microbiota transplantation (FMT); 3) weekly clinical assessments during eight weeks. The follow-up period is 90 days. The primary outcome is 90-day survival from the date of positive CDI PCR test. Patient-related secondary outcome measures include quality of life measured by EQ-5D-5L and by the Overall Quality of Life Depression List (OQoL-DL) and functional status measured by the Functional Recovery Score (FRS). Quality-related secondary outcome measures include time-to-treatment with FMT, time-to-treatment with vancomycin, CDI recurrence, readmission, and days in hospital.Discussion: This study will provide new knowledge on the effects of a geriatric tailored intervention for older patients with CDI, including an early assessment of the indication for FMT.Trial registration: The study was pre-registered at ClinicalTrials.gov on 28 June, 2022. Study identifier: NCT05447533.
Sharp coefficients bounds for Starlike functions associated with Gregory coefficients
Authors: Kazımoğlu Sercan , Deniz Erhan , Srivas H. M. 
Published: April 2023

Abstract
In this paper we introduced the class SG* of analytic functions which is related with starlike functions and generating functionof Gregory coefficients. By using bounds on some coefficient functionals for the family of functions with positive real part, we obtain several sharp coefficient bounds on the first six coeffcients and also further sharp bounds on the corresponding Hankel determinants for functions in the class SG*. Additionally, the sharp bounds for logarithmic and inverse coefficients of functions belonging to the considered class SG* were estimated.
Mathematics Subject Classification (2010). Priminary 30C45; Secondary 30C50, 30C80.
Gender versus sex in predicting outcomes of traumatic brain injury: A cohort study utilizing large administrative databases
Authors: Teterina Anastasia , Zulbayar Suvd , Mollayeva Tatyana , Chan Vincy , Colantonio Angela , Escobar Michael 
Published: April 2023

Abstract

Understanding the factors associated with elevated risks and adverse consequences of traumatic brain injury (TBI) is an integral part of developing preventive measures for TBI. Brain injury outcomes differ based on one’s sex (biological characteristics) and gender (social characteristics reflecting norms and relationships), however, whether it is sex or gender that drives differences in early (30-day) mortality and discharge location post-TBI event are unknown. In the absence of gender variable in existing data, we developed a method for “measuring gender” in 276,812 residents of Ontario, Canada who entered the emergency department and acute care hospitals with a TBI diagnostic code between April 1st, 2002 and March 31st, 2020. We analysed differences in diagnostic codes between the sexes to derive gender score that reflected social dimensions. Sex had a significant effect on early mortality after severe TBI with a rate ratio (95% confidence interval (CI)) of 1.54 (1.24-1.91). Gender had a more significant effect than sex on discharge location. A person expressing more female-like characteristics have lower odds of being discharged to rehabilitation versus home with odds ratio (95% CI) of 0.54 (0.32-0.88). The method we propose offers an opportunity to measure gender effect independently of sex on TBI outcomes.
Adoption of global circular waste management systems is crucial to cut leakage of waste into aquatic environments
Authors: Sanabria Adriana Gomez , Lindl Florian 
Published: April 2023

Abstract

Waste leakage has become a major global concern due to the negative impacts on aquatic ecosystems and human health. By contrasting baseline with mitigation scenarios, our study combines spatial analysis with the Shared Socioeconomic Pathways storylines to develop plausible future waste leakage mitigation strategies up to 2040. Our study indicates that the leakage of MSW to the aquatic environments is highly dependent on population size, populated area (urban – rural), physical environment presence, length and area of aquatic systems, waste generation and composition, and level of waste management systems. We found that not necessarily countries exhibiting the highest amounts of uncollected waste coincide with countries having the highest waste leakage in the aquatic environments. The results show that the adoption of circular waste management systems would be an active mitigation strategy that could stop waste from entering the aquatic ecosystems in the first place. However, even in a scenario representing a sustainable world in which technical, social, and financial barriers are overcome and public awareness and participation to reduce, reuse and recycling waste exists, it would be impossible to mitigate and eliminate waste leakage before 2030. This translates into a failure to meet the waste-related Sustainable Development Goals.
Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line
Authors: Lončarić Marija , Stojanović Nikolina , Justament Anja Rac , Coopmans Kaatje , Majhen Dragomira , Humphries Jonathan D , Humphries Martin J , Ambriovic-Ristov Andreja 
Published: April 2023

Abstract

BackgroundFocal adhesions (FAs) are integrin-containing, multi-protein structures that link intracellular actin to the extracellular matrix and trigger multiple signaling pathways that control cell proliferation, differentiation, survival and motility. Microtubules (MTs) are stabilized in the vicinity of FAs through interaction with the components of the cortical microtubule stabilising complex (CMSC). KANK (KN motif and ankyrin repeat domains) family proteins within the CMSC, KANK1 or KANK2, bind talin within FAs and thus mediate actin-MT crosstalk. We previously identified in MDA-MB-435S cells, which preferentially use integrin αVβ5 for adhesion, KANK2 as a key molecule enabling the actin-MT crosstalk. KANK2 knockdown also resulted in increased sensitivity to MT poisons, paclitaxel (PTX) and vincristine and reduced migration. Here, we aimed to analyze whether KANK1 has a similar role and to distinguish which talin isoform binds KANK2.MethodsThe cell model consisted of human melanoma cell line MDA-MB-435S and stably transfected clone with decreased expression of integrin αV (3αV). For transient knockdown of talin1, talin2, KANK1 or KANK2 we used gene-specific siRNAs transfection. Using previously standardized protocol we isolated integrin adhesion complexes. SDS-PAGE and Western blot was used for protein expression analysis. The immunofluorescence analysis and live cell imaging was done using confocal microscopy. Cell migration was analyzed with Transwell Cell Culture Inserts. Statistical analysis using GraphPad Software consisted of either one-way analysis of variance (ANOVA), unpaired Student’s t-test or two-way ANOVA analysis.ResultsWe show that KANK1 is not a part of the CMSC associated with integrin αVβ5 FAs and its knockdown did not affect the velocity of MT growth or cell sensitivity to PTX. The talin2 knockdown mimicked KANK2 knockdown i.e. led to the perturbation of actin-MT crosstalk, which is indicated by the increased velocity of MT growth and increased sensitivity to PTX and also reduced migration.ConclusionWe conclude that KANK2 functionally interacts with talin2 and that the mechanism of increased sensitivity to PTX involves changes in microtubule dynamics. These data elucidate a cell-type-specific role of talin2 and KANK2 isoforms and we propose that talin2 and KANK2 are therefore potential therapeutic targets for improved cancer therapy.
Machinability Study of Super Duplex Stainless Steel S32750 with Magnetorheological Fluid Assisted Nano Finished Cutting Tool Inserts
Authors: Thiyagu M. , Anbuchezhiyan G. , Elanchezhian J. , Palani Kumaran , Narendranathan S.K 
Published: April 2023

Abstract
To improve tribological properties in the tool chip contact zone, coated carbide tool insert surfaces are nano-finished using magnetorheological fluid (MRF) with diamond abrasives. In order to polish surfaces without significantly increasing the danger of damage to the tool's cutting blades, the configuration of the magnetic particle chain feeding the abrasives is essential. The CNMG 120408-F3M IC807 ISCAR make coated carbide inserts as received have an average surface roughness of 90 nm on the rake face and 110 nm on the flank surface. This unique MRF-assisted tool finishing process results in surface roughness of the tool inserts of less than 30 nm on the flank and less than 48 nm on the rake face. Turning super duplex stainless steel under dry cutting circumstances encourages the use of environmentally friendly machining methods. The machinability characteristics of the nano finished inserts are investigated in the dry turning of S32750 super duplex stainless steel based on surface roughness, cutting force, and tool wear. Compared to unprocessed tools, MRF-assisted nano finished tools demonstrated up to 30% longer tool life spans. The average tool life for nano-polished inserts is 27 mins, compared to 19 mins for unprocessed inserts for a tool life criterion of max. flank wear land, VB = 500 µm, at a cutting speed of 108 m/min, a feed rate of 0.212 mm/rev, and a depth of cut of 1.2 mm. Turning an S32750 super duplex stainless steel material has also seen an 18% reduction in cutting forces attributed to the use of nano polished inserts that also provide excellent lubricity. In terms of cutting forces, flank wear, and surface roughness, the results show that nano polished inserts perform better than conventional inserts.
Effects of insecurity on inflation in Burkina Faso
Authors: SIRY Abdoulaye , TRAORE Inoussa 
Published: April 2023

Abstract
The price increase has been exacerbated in Burkina Faso compared to other member countries of the West African Economic and Monetary Union. According to the existing literature, plausible explanations for this galloping inflation include the recent health crisis and the economic policy measures taken. However, inflation persists, although the health crisis has subsided. This paper highlights persistent insecurity's effects on inflation in Burkina Faso. ARDL modeling on monthly data from January 2019 to April 2022 was used. The analysis results show that the influx of internally displaced persons (IDPs) and deteriorating agro-climatic conditions drive inflation in Burkina Faso in the short and long term. The marginal effects of IDPs on inflation are about 0.09640, 0.08917, 0.1043, and 0.07827 percent after three, two, one month, and at the current time, respectively. It is recommended that short-term actions support IDPs, such as food allocations and long-term actions. Actions to improve agro-climatic conditions, such as irrigation techniques, should be supported. Indeed, any anti-inflationary policy should take into account non-monetary and monetary factors.
JEL Classification : E31 • J15 • J61 • Q15
Nursing Management of Patients Dealing with Spina Bifida: from the Prenatal Diagnosis to Adulthood / Nursing Intervention for the Improvement of the Impact of Urinary and Fecal Incontinence on the Quality of Life of People Dealing with Spina Bifida
Authors: Calabrese Fabiana , Poziello Antonio , Spiezia Gennaro , Rotunno Tiziana , Chervino Ciro , Iannicelli Anna Maria 
Published: April 2023

Abstract
Background Urinary and fecal incontinence in people dealing with spina bifida, has inevitably an influence on the quality of life. In this analysis, the degree of education on how to manage incontinence and retention is studied, as well as the problems those might create and the consequential degree of autonomy and independence reached into the management of those. The main goal is to increase both nursing assistance and the education of the people dealing with spina bifida.Methods 125 people affected by spina bifida, belonging to the ASBI (Associazione Spina Bifida Italia) decided to file a survey concerning the bowel and bladder management. The survey was done through the “Google Docs” platform, with a link that was then shared to the members of the association by the secretariat of the association itself.Results out of 125 participants, 80 were females and 25 males. The questions concerned the level of deambulation (the 35,2% was autonomous, the 30,4% were people who use wheelchairs while the 34,4% is aid-supported), urinary incontinence, with great concern to the self-catheterization technique (the 80,8% claimed to be autonomous in performing self-catheterization, unlike the remaining 19,2%) and the impact of the said incontinence on social life (the 59,2% claimed they do not feel restrained because of their bladder incontinence or retention, unlike the remaining 40,8%). Lastly, we focused on fecal constipation and incontinence (the 57,6% claimed to struggle with incontinence, the 12% claimed they don’t and the 30,4% struggles with both conditions), on the ability of the people dealing with this to intervene to prevent unpleasant situations, in particular by using trans-anal irrigation (the 57,6% doesn’t feel autonomous in performing it).Conclusion urinary and fecal incontinence have, of course, an impact on the quality of life of people dealing with spina bifida. Nevertheless, we can observe that it is possible to improve the quality of life of these people, letting them feel confident enough to take part in social activities, through education from an incredibly young age, supplied by the medical staff and mostly by the parents (previously educated by the medical staff as well).
Qualitative interviews with Doctor of Pharmacy Graduates on Care Provision to Patients with Mental Illness after a Psychiatric Rotation
Authors: Zolezzi Monica , Ghanem Rawan , Elamin Shahd , Eltorki Yassin 
Published: April 2023

Abstract

Background:Pharmacists are vital to optimizing therapy of patients with mental illness. However, lack of knowledge in mental health, decreased confidence, and stigma could add to pharmacists’ reluctance to provide pharmaceutical care to patients with mental illness. Advanced Practice Pharmacy Experiences in mental health practice can provide valuable learning opportunities and potentially aid in overcoming these barriers to safe and effective mental health care upon graduation.Aim:This study aims to explore the attitudes of PharmD graduates towards provision of pharmaceutical care to patients with mental illness after undergoing a psychiatric rotation.Methods:A qualitative design was used. PharmD graduates who had completed a psychiatric rotation during their PharmD studies were invited to participate in a semi-structured interview. Interviews were recorded, transcribed, and analysed inductively using thematic analysis.Results:Interviews with PharmD graduates revealed five themes that revolved around prior familiarity to mental health, impression of the rotation, views on stigma, barriers to the rotation, and the positive impact of the rotation while in practice. Although participants started the mental health rotation with low confidence and a sense of fear, they described their experience as unique, eye-opening, and insightful. The participants limited knowledge and familiarity with mental health patients and conditions prior to initiating the rotation were perceived as challenges to achieve full confidence in the provision of mental health care during practice.Conclusion:For the most part, APPE rotation in psychiatry was viewed as a positive opportunity for enhancing the PharmD graduates’ insight, knowledge and skills for the provision of pharmaceutical care to patients with mental illness.
Multiscale Relevance of Natural Images
Authors: Lakhal Samy , Darmon Alexandre , Mastromatteo Iacopo , Marsili Matteo , Benzaquen Michael 
Published: April 2023

Abstract
We use an agnostic information-theoretic approach to investigate the statistical properties of natural images. We introduce the Multiscale Relevance (MSR) measure to assess the robustness of images to compression at all scales. Starting in a controlled environment, we characterize the MSR of synthetic random textures as function of image roughness $\text H$ and other relevant parameters. We then extend the analysis to natural images and find striking similarities with critical ($\text{H}\approx 0$) random textures. We show that the MSR is more robust and informative of image content than classical methods such as power spectrum analysis. Finally, we confront the MSR to classical measures for the calibration of common procedures such as color mapping and denoising. Overall, the MSR approach appears to be a good candidate for advanced image analysis and image processing, while providing a good level of physical interpretability.
Experiences of Hospital Clinical Nurse Educator Role Adaptation: A Meta- Synthesis
Authors: Kim Jeonghyun 
Published: April 2023

Abstract
Background: Hospital clinical nurse educators are becoming important in helping experienced nurses improve their professionalism and facilitating transition of new nurses. Because becoming a nurse educator requires a variety of competencies, hospital clinical nurse educators experience stress and lack of control during the transition from general nurse to educator.
Purpose: To synthesize experiences of hospital clinical nurse educators in the process of role adaptation.
Method: A qualitative meta‐synthesis was conducted according to thematic synthesis methods of Thomas and Harden. Systematic literature review flow chart of Preferred Reporting Items for Systematic Reviews and Meta-Analysis was used for literature search and selection. Quality appraisal was performed according to Joanna Briggs Institute Qualitative Assessment and Review Instrument.
Results:Hospital clinical nurse educator's experience of role adaptation from four studies appeared in a total of seven themes synthesized into the following: 1) getting out of comfort zone to the unknown; 2) unfamiliar relationships in familiar environments; and 3) growing together through teaching and learning.
Conclusion: Supports are needed to promote transition of hospital clinical nurse educators to improve the quality of nursing education.
Waste Reduction via Computer Vision-based Inspection: Towards Lean Systems in Metal Production
Authors: Shahin Mohammad , Chen F. Frank , Hosseinzadeh Ali , Maghanaki Mazdak 
Published: April 2023

Abstract
The global steel demand continues to increase, with steel being used in various industries, including construction, automobile, national defense, and machinery. However, steel production is a delicate process that can result in different defects on the steel surface, negatively affecting the quality of the steel products. Therefore, recognizing metal surface defects is critical in the metal production industry. Manual detection of these defects is the standard method, but it is time-consuming, labor-intensive, and prone to subjective factors, leading to low accuracy and unreliable results. Automated defect detection using computer vision methods can replace or supplement manual detection. In recent years, machine learning algorithms, particularly Convolutional Neural Networks (CNNs), have shown great promise in achieving high accuracy rates in this task. In addition, image classification algorithms can contribute to Lean metal production by identifying defects or anomalies in the manufacturing process, which can be used to reduce waste and increase efficiency. However, the performance and cost of different CNN architectures can vary widely, making it challenging for decision-makers to select the most suitable model. This paper analyzes various CNN-based image classification algorithms, including MobileNet, ShuffleNet, DenseNet, RegNet, and NasNet, in classifying steel surface defects in the NEU-CLS-64 dataset. We evaluate their performance using metrics such as accuracy, precision, sensitivity, specificity, F1 score, and G-mean, and benchmark these models against each other. Our findings revealed that RegNet achieved the highest accuracy, precision, sensitivity, specificity, F1 score, and G-mean performance but at a higher cost than other models. Meanwhile, MobileNet had the lowest performance. The results provide decision-makers with valuable insights into selecting the most suitable CNN model for steel surface defect detection based on their performance.