bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perancangan Tekstil Dengan Sumber Ide Griffin Untuk Fesyen Komunitas Solo Kick’s Up
Authors: Pradana Bagus Firman , Rizali Nanang 
Published: May 2023

This design developed Griffin as a basis for making textiles and functioned in the sneakerhead community fashion named Solo Kick’s Up, this activity was an introduction to a nature and identity, depicting the digital world while offering unique and interesting visuals. The purpose of this design is to develop an illustration design motif with popular visual art processing with consideration of the fashion function for the Solo Kick’s Up community. The method used consists of; design methods, design concepts and visualizations. The design method goes through the stages of problem analysis, problem solving strategies, data collection, testing, and determining the initial design ideas. The design concept includes the rationale for designing textiles. Visualization is the stage of visualizing the concept of a design plan.The results of this textile design are as follows: (1) Greek mythological creature Griffin as a source of textile design ideas in order to increase the value of textiles, The results of the design succeeded in making 7 textile designs. (2) The application of Griffin textile design as a community fashion produces outer fashion products that are memorable, attractive, unique and different from the others.
Gambar Pitutur Punakawan sebagai Inspirasi Penciptaan Video Kanal Tunggal
Authors: Triadiputra Stephanus Andre , Waskito Setyo Bagus 
Published: May 2023

The rapid development of technology makes the world has no real boundaries. Dissemination of information occurs very quickly and easily. Modern society at all ages, most of them have equipment that allows them to be directly connected to information, entertainment and knowledge that comes from anywhere. As a result, clash of local values with foreign or external values is unavoidable. Javanese proverbs that often appear through pictures of pitutur clowns (Semar, Gareng, Petruk, and Bagong) in glass paintings have noble values that are useful for character building, especially for Javanese people. Pitutur pictures usually contain suggestions and prohibitions in life. Video illustration of the existing pitutur images, made with the chroma key (green screen) technique as the creation method used for its embodiment. As a result, single channel videos which are illustrations of pitutur images can be used as a medium for spreading the noble values of Javanese culture in the current millennial era.
Color Grading sebagai Pembangun Mood pada Setting Waktu dalam Web Series Rewrite
Authors: Yanaayuri Shabira Almaas , Agung I Putu Suhada 
Published: May 2023

Color grading can be used to support the film’s narrative by creating an atmosphere or mood that complements the storyline. This study aims to analyze and describe color grading as a mood builder that is applied to time settings in Web Series Rewrite. The results of this study found that color grading in several scenes at each time setting in Web Series Rewrite is used to build the mood or atmosphere in the story. The colors that are widely used include blue and brown with a mixture of other colors, namely: red, gray and black. Light blue is used to build the atmosphere of a scene that seems cold and melancholy, brown is used to build the atmosphere of a scene that seems warm, and dark brown and reddish brown tend to build a dark atmosphere and angry conflict. The use of gray color gives a gloomy and sad impression.
Penerapan Struktur Penceritaan pada Film Dua Garis Biru Berdasarkan Pendekatan Sequence
Authors: Apriyono Angga Setyo , Setiawati Sri Wastiwi 
Published: May 2023

This study aims to describe the application of the story structure in the film Dua Garis Biru based on Paul Joseph Gulino’s sequence approach. The research method used is qualitative research. The results showed that the structure of the story used in the film Dua Garis Biru uses an eight-sequence story structure approach. Sequence 1 begins with the introduction of the main characters Dara and Bima with their lives, and there is a point of attack when it is confirmed that Dara is pregnant due to having sex with Bima. Sequence 2 introduces the limitations of Dara and Bima which affect the way they will run to overcome the problem by covering up Dara’s pregnancy. Sequence 3 Bima and Dara began to carry out their plan but an unexpected obstacle appeared that made Dara’s pregnancy revealed which resulted in Dara having to be expelled from school and expelled from the house. Sequence 4 shows how poorly prepared the characters are and the midpoint culmination appears. Sequence 5 shows the consequences of the midpoint culmination which makes Bima finally married to Dara, although a bigger problem arises. Sequence 6 shows the consequences of a big problem at the end of sequence 5 leading Dara to realize that they have not been able to become parents, which makes Dara and Bima do the last resort which is risky. At the beginning of sequence 7 an unexpected problem arose from Dara and Bima’s final plan, which made them aware of the importance of the role of parents in children’s growth, then led to a twist, namely Bima finally chose to take care of his own child. Sequence 8 problems were finally resolved, Bima took care of his son and Dara went to Korea.
Visualisasi Feminisme dalam Film Jelita Sejuba: Mencintai Kesatria Negara melalui Karakter Syarifah
Authors: Septiana Agnes , Sjafi'i Achmad 
Published: May 2023

Jelita Sejuba movie: Loving the Knights of the Country is examined in terms of visualizing the feminism of the film’s main character, namely Syarifah. Although not a feminist movie, there are indications of feminism features expressed by Syarifah’s character through visual language. The purpose of this research is to describe the visualization of feminism through shots, scenes, gestures, and dialogues. This qualitative descriptive study applies a purposive sampling method by selecting the most appropriate scene as a sample. The analysis of feminism in this study is seen from the scenes which contain the visualization of feminism. The results of this study conclude that feminism can be presented through shots in movies that summarize scenes, gestures, and dialogues. The visualization of feminism presented in the movie shows Syarifah’s attitude toward gaining the right to choose life according to her preferences.
Cervical Cancer Screening and Prevention in Low- and Middle-Income Countries: A Perspective from Bangladesh
Authors: Deeba Iztiba Mallik , Hossain Mohammad Sorowar 
Published: May 2023

Cervical cancer is a major public health concern for women worldwide, particularly in low- and middle-come countries (LMICs). Despite a large number of women (nearly 58 million) are at risk of this preventable cancer, the issue of cervical cancer has not become a public health priority in Bangladesh. The understanding of the challenges and opportunities in Bangladesh about cervical cancer would provide valuable insights for other LMICs also. In this article, we review the epidemiology, risk factors, awareness and treatment of cervical cancer in the context of Bangladesh. Due to lack of awareness and an organized national screening program, the majority of patients are generally diagnosed at the advantaged stages of disease, in spite of having a big window of screening opportunity at precancer stage. Most LMICs lack resources for developing a parallel health service system dedicated for cancer prevention and management. In this context, we propose some recommendations including a cost-effective screening strategy by capitalizing available resources of COVID-19 diagnostic and GenXpert labs, and an innovative female-centric primary healthcare workers and high school-based approaches for generating awareness on cervical cancer risk factors, screening and vaccination. Our proposed strategy could also be effective for other similar settings in LMICs.
Bangladesh J Microbiol, Volume 39, Number 2, December 2022, pp 76-82
Encephaloceles frontoethmoidal: revisão bibliográfica
Authors: Nunes Laura Andrezza de Barros , Mota Américo , Santana Aquino , Valois Rafael 
Published: May 2023

A encefalocele é uma doença de característica congênita, quando relacionada a um defeito no tubo neural e formação de sacos herniários que variam de composição e se formam externamente ao crânio por consequência a algum defeito ósseo ou adquirida, em decorrência de traumas, tumores e lesões iatrogênicas. O seu tipo varia de acordo com a localização das alterações. A etiologia dessa patologia ainda não é muito bem esclarecida. Tendo em vista a escassez de estudos atualizados em torno dessa temática, esse trabalho trata-se de uma revisão de literatura que tem como objetivo contribuir, com base em uma revisão de literatura, reunindo os principais achados dessa patologia, integrando aspectos clínicos, radiológicos e terapêuticos. Foi realizado uma revisão narrativa de literatura nos meses de março e abril de 2023, por meio de pesquisa em base de dados: PubMed, SciELO e Google Acadêmico. Os descritores utilizados foram Frontoethmoidal encephaloceles, Frontoethmoidal encephaloceles diagnosis e Frontoethmoidal encephaloceles radiology filtrados nos últimos 10 anos. O seu diagnóstico pode ser feito através de métodos como RM em sequências ponderadas em T1 e T2 em planos sagital, axial, coronal e FLAIR, além da TC. Quadros de encefalocele anterior podem ainda cursar com obstrução nasal, fenda nasal, rinorreia de LCR, telecanto e anomalia orbitária. Portanto, ao analisarmos as manifestações encontradas na encefalocele frontoetmoidal, podemos inferir que é de suma importância reconhecer os sinais clínicos dessa patologia, bem como incentivar novos estudos para esclarecer o assunto em questão.
A novel model for predicting a composite outcome of major complications after valve surgery
Authors: Cheng Zhenzhen , Wang Yishun , Liu Jing , Ming Yue , Yao Yuanyuan , Wu Zhong , Guo Yingqiang , Du Lei , Yan Min 
Published: May 2023

BackgroundOn-pump valve surgeries are associated with high morbidity and mortality. The present study aimed to reliably predict a composite outcome of postoperative complications using a minimum of easily accessible clinical parameters.MethodsA total of 7,441 patients who underwent valve surgery were retrospectively analyzed. Data for 6,220 patients at West China Hospital of Sichuan University were used to develop a predictive model, which was validated using data from 1,221 patients at the Second Affiliated Hospital of Zhejiang University School of Medicine. The primary outcome was a composite of major complications: all-cause death in hospital, stroke, myocardial infarction, and severe acute kidney injury. The predictive model was constructed using the least absolute shrinkage and selection operator as well as multivariable logistic regression. The model was assessed in terms of the areas under receiver operating characteristic curves, calibration, and decision curve analysis.ResultsThe primary outcome occurred in 129 patients (2.1%) in the development cohort and 71 (5.8%) in the validation cohort. Six variables were retained in the predictive model: New York Heart Association class, diabetes, glucose, blood urea nitrogen, operation time, and red blood cell transfusion during surgery. The C-statistics were 0.735 (95% CI, 0.686–0.784) in the development cohort and 0.761 (95% CI, 0.694–0.828) in the validation cohort. For both cohorts, calibration plots showed good agreement between predicted and actual observations, and ecision curve analysis showed clinical usefulness. In contrast, the well-established SinoSCORE did not accurately predict the primary outcome in either cohort.ConclusionsThis predictive nomogram based on six easily accessible variables may serve as an “early warning” system to identify patients at high risk of major complications after valve surgery.Clinical Trial Registration[www.ClinicalTrials.gov], identifier [NCT04476134].
A plasma proteomic approach in patients with heart failure after acute myocardial infarction: insights into the pathogenesis and progression of the disease
Authors: Liu Yan , Huang Da , Li Zhile , Zhou LiuFang , Cen Tuan , Wei Baomin , Wei Liuqing , Wu Hongying , Su Liye , Sooranna Suren R. , Pan Xinshou , Huang ZhaoHe 
Published: May 2023

AimsThe pathogenesis of disease progression targets for patients with heart failure after acute myocardial infarction was investigated by using plasma proteomics.MethodsThe plasma proteomes of acute myocardial infarction patients with (MI-HF) and without (MI-WHF) heart failure were compared. Each group consisted of 10 patients who were matched for age and sex. The peptides were analyzed by 2-dimensional liquid chromatography coupled to tandem mass spectrometry in a high definition mode. Parallel reaction monitoring (PRM) verified the selected target proteins.ResultsWe identified and quantified 2,589 and 2,222 proteins, respectively, and found 117 differentially expressed proteins (DEPs) (≥1.5-fold), when the MI-HF and MI-WHF groups were compared. Of these 51 and 66 were significantly up-regulated and down-regulated, respectively. The significant DEPs was subjected to protein–protein interaction network analysis which revealed a central role of the NF-κB signaling pathway in the MI-HF patients. PRM verified that MB, DIAPH1, VNN1, GOT2, SLC4A1, CRP, CKM, SOD3, F7, DLD, PGAM2, GOT1, UBA7 and HYOU1 were 14 proteins which were highly expressed in MI-HF patients.ConclusionsThese findings showed a group of proteins related to the NF-κB signaling pathway in the pathogenesis of patients with poor outcomes after experiencing MI-HF. These proteins may be useful candidate markers for the diagnosis of MI-HF as well as help to elucidate the pathophysiology of this major cause of mortality in older patients.
Impact of pacing mode and different echocardiographic parameters on cardiac output (PADIAC)
Authors: Blessberger Hermann , Kammler Juergen , Kellermair Joerg , Kiblboeck Daniel , Nahler Alexander , Hrncic Denis , Saleh Karim , Schwarz Stefan , Reiter Christian , Fellner Alexander , Eppacher Christian , Sheldon Todd J. , Steinwender Clemens 
Published: May 2023

IntroductionThe extent of the hemodynamic benefit from AV-synchronous pacing in patients with sinus rhythm and AV block is not completely understood. Thus, we systematically investigated the association of an array of echocardiographic and epidemiological parameters with the change in cardiac output depending on the stimulation mode (AV-synchronous or AV-asynchronous pacing).MethodsPatients in sinus rhythm after previous dual chamber pacemaker implantation underwent a thorough basic echocardiographic assessment of diastolic and systolic left ventricular function, and atrial function (26 echo parameters, including novel speckle tracking strain measurements). Then, stroke volume was measured with AV-synchronous (DDD) and AV-asynchronous (VVI) pacing. Each patient represented their own control, and the sequence of stroke volume measurements was randomized.ResultsIn this prospective single-center study (NCT04068233, registration August 22nd 2019), we recruited 40 individuals. The stroke volume was higher in all patients when applying AV-synchronous DDD pacing [median increase 12.8 ml (16.9%), P &lt; 0.001]. No echo parameter under investigation was associated with the extent of stroke volume increase in a linear regression model. Of all epidemiological variables, a history of acute myocardial infarction (AMI) was associated with an attenuated stroke volume gain in a univariate and a multivariate regression model that adjusted for confounders. A- and S-wave velocities were reduced in the AMI group.DiscussionIn our cohort of patients, each subject benefited from AV-synchronous DDD pacing. No single echo parameter could predict the amount of stroke volume increase. The beneficial effect of AV-synchronous pacing on stroke volume was attenuated after prior acute myocardial infarction.ClinicalTrials.gov identifier (NCT number): NCT04068233.
Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers
Authors: Zhong Ce , Wu Chen , Lin Yuan , Lin Dongxin 
Published: May 2023

Objectives: This study aimed to explore cell type level expression quantitative trait loci (eQTL) in adenocarcinoma at the gastroesophageal junction (ACGEJ) and identify susceptibility and prognosis markers.Methods: Whole-genome sequencing (WGS) was performed on 120 paired samples from Chinese ACGEJ patients. Germline mutations were detected by GATK tools. RNA sequencing (RNA-seq) data on ACGEJ samples were taken from our previous studies. Public single-cell RNA sequencing (scRNA-seq) data were used to produce the proportion of epithelial cells. Matrix eQTL and a linear mixed model were used to identify condition-specific cis-eQTLs. The R package coloc was used to perform co-localization analysis with the public data of genome-wide association studies (GWASs). Log-rank and Cox regression tests were used to identify survival-associated eQTL and genes. Functions of candidate risk loci were explored by experimental validation.Results: Refined eQTL analyses of paired ACGEJ samples were performed and 2,036 potential ACGEJ-specific eQTLs with East Asian specificity were identified in total. ACGEJ-gain eQTLs were enriched at promoter regions more than ACGEJ-loss eQTLs. rs658524 was identified as the top eQTL close to the transcription start site of its paired gene (CTSW). rs2240191–RASAL1, rs4236599–FOXP2, rs4947311–PSORS1C1, rs13134812–LOC391674, and rs17508585–CDK13-DT were identified as ACGEJ-specific susceptibility eQTLs. rs309483–LINC01355 was associated with the overall survival of ACGEJ patients. We explored functions of candidate eQTLs such as rs658524, rs309483, rs2240191, and rs4947311 by experimental validation.Conclusion: This study provides new risk loci for ACGEJ susceptibility and effective disease prognosis biomarkers.
The importance of chest CT severity score and lung CT patterns in risk assessment in COVID-19-associated pneumonia: a comparative study
Authors: Szabó Miklós , Kardos Zsófia , Kostyál László , Tamáska Péter , Oláh Csaba , Csánky Eszter , Szekanecz Zoltán 
Published: May 2023

IntroductionChest computed tomography (CT) is suitable to assess morphological changes in the lungs. Chest CT scoring systems (CCTS) have been developed and use in order to quantify the severity of pulmonary involvement in COVID-19. CCTS has also been correlated with clinical outcomes. Here we wished to use a validated, relatively simple CTSS to assess chest CT patterns and to correlate CTSS with clinical outcomes in COVID-19.Patients and methodsAltogether 227 COVID-19 cases underwent chest CT scanning using a 128 multi-detector CT scanner (SOMATOM Go Top, Siemens Healthineers, Germany). Specific pathological features, such as ground-glass opacity (GGO), crazy-paving pattern, consolidation, fibrosis, subpleural lines, pleural effusion, lymphadenopathy and pulmonary embolism were evaluated. CTSS developed by Pan et al. (CTSS-Pan) was applied. CTSS and specific pathologies were correlated with demographic, clinical and laboratory data, A-DROP scores, as well as outcome measures. We compared CTSS-Pan to two other CT scoring systems.ResultsThe mean CTSS-Pan in the 227 COVID-19 patients was 14.6 ± 6.7. The need for ICU admission (p &lt; 0.001) and death (p &lt; 0.001) were significantly associated with higher CTSS. With respect to chest CT patterns, crazy-paving pattern was significantly associated with ICU admission. Subpleural lines exerted significant inverse associations with ICU admission and ventilation. Lymphadenopathy was associated with all three outcome parameters. Pulmonary embolism led to ICU admission. In the ROC analysis, CTSS&gt;18.5 significantly predicted admission to ICU (p = 0.026) and CTSS&gt;19.5 was the cutoff for increased mortality (p &lt; 0.001). CTSS-Pan and the two other CTSS systems exerted similar performance. With respect to clinical outcomes, CTSS-Pan might have the best performance.ConclusionCTSS may be suitable to assess severity and prognosis of COVID-19-associated pneumonia. CTSS and specific chest CT patterns may predict the need for ventilation, as well as mortality in COVID-19. This can help the physician to guide treatment strategies in COVID-19, as well as other pulmonary infections.
Functional limitation as a mediator of the relationship between multimorbidity on health-related quality of life in Australia: evidence from a national panel mediation analysis
Authors: Lee John Tayu , Ishida Marie , Haregu Tilahun , Pati Sanghamitra , Zhao Yang , Palladino Raffaele , Anindya Kanya , Atun Rifat , Oldenburg Brian , Marthias Tiara 
Published: May 2023

ObjectiveThe inverse relationships between chronic disease multimorbidity and health-related quality of life (HRQoL) have been well-documented in the literature. However, the mechanism underlying this relationship remains largely unknown. This is the first study to look into the potential role of functional limitation as a mediator in the relationship between multimorbidity and HRQoL.MethodsThis study utilized three recent waves of nationally representative longitudinal Household, Income, and Labor Dynamics in Australia (HILDA) surveys from 2009 to 2017 (n = 6,814). A panel mediation analysis was performed to assess the role of functional limitation as a mediator in the relationship between multimorbidity and HRQoL. The natural direct effect (NDE), indirect effect (NIE), marginal total effect (MTE), and percentage mediated were used to calculate the levels of the mediation effect.ResultsThis study found that functional limitation is a significant mediator in the relationship between multimorbidity and HRQoL. In the logistic regression analysis, the negative impact of multimorbidity on HRQoL was reduced after functional limitation was included in the regression model. In the panel mediation analysis, our results suggested that functional limitation mediated ~27.2% (p &lt; 0.05) of the link between multimorbidity and the composite SF-36 score for HRQoL. Functional limitation also mediated the relationship between the number of chronic conditions and HRQoL for each of the eight SF-36 dimensions, with a proportion mediated ranging from 18.4 to 28.8% (p &lt; 0.05).ConclusionFunctional status has a significant impact on HRQoL in multimorbid patients. Treatment should concentrate on interventions that improve patients' functioning and mitigate the negative effects of multimorbidity.
Aniline-induced production of aniline-containing polyketides and related bicyclic polyketides by the Yellow River wetland-derived fungus Talaromyces funiculosus
Authors: Wang Zhenhui , Li Zhanlin , Niu Chao , Yang Lanping , Zhai Yangyang , Li Dehai , Wu Guangwei , Zhang Zhenzhen , He Xueqian 
Published: May 2023

Introduction and MethodsSilencing gene activation can effectively enrich the diversity of fungal secondary metabolites.Results and DiscussionCultivation of the Yellow River wetland-derived fungus Talaromyces funiculosus HPU-Y01 with aniline led to the isolation of one new aniline-containing polyketide tanicutone A (1), two new bicyclic polyketides tanicutones B-C (2–3), a new related trienoic acid 8-methyldeca-2,4,6-trienoic acid (5), and a known compound 4. The planar structures and configurations of 1–5 were determined by NMR, MS, and ECD calculations. Compound 2 featured a key aldehyde group and showed promising inhibitory activity against Vibrio parahaemolyticus with a minimum inhibitory concentration (MIC) value of 0.17 μg/mL. This is a rare report of aniline-induced fungal production of tetrahydronaphthone polyketides.