bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synergism of triazine containing dopamine to flame retardancy, smoke suppression, and mechanical properties of thermoplastic polyurethane/ammonium polyphosphate
Authors: Xu Yao , Wang Bingtao , Guo Zhenghong , Fang Zhengping , Li Juan , Chen Peng 
Published: July 2023

AbstractA dopamine‐triazine compound (TTD) was synthesized by using dopamine and cyanuric chloride. The TTD and ammonium polyphosphate (APP) were combined to improve the flame retardancy of thermoplastic polyurethane (TPU). The flame retardancy, thermal stability and mechanical properties of TPU blends were investigated. TPU containing 8 wt% APP displays a UL‐94 V0 rating and a limiting oxygen index (LOI) of 30.0 vol%. When APP and TTD are combined at a ratio of 7/1 (wt%/wt%), only 5 wt% flame retardant is needed to endow TPU with a UL‐94 V0 rating, suggesting that a good synergistic effect exists between APP and TTD on enhancing flame retardancy of TPU. In addition, TTD reduces the heat release rate of TPU, suppresses the smoke and toxic gas release and promotes the formation of an intumescent char layer with few defects during combustion. In addition, TTD improves the tensile properties of TPU/APP blends.
Osteophilic and Dual‐Regulated Alendronate‐Gene Lipoplexes for Reversing Bone Loss
Authors: Li Junjie , Zhang Ruizhi , Du Yawei , Liu Gongwen , Dong Yu , Zheng Miao , Cui Wenguo , Jia Peng , Xu Youjia 
Published: July 2023

AbstractThe pathogenesis of postmenopausal osteoporosis (PMOP) is mainly determined by the adhesion of osteoclasts to the bone matrix and the involvement of various molecules in bone resorption. The dual regulation strategy of the physical barriers of bone matrix and intracellular gene regulation generated by advanced biomaterials is a decent alternative for the treatment of PMOP. Herein, for the first time, it is identified that hsa‐miR‐378i/mmu‐miR‐378a‐3p are closely associated with PMOP. Then, an osteophilic and dual‐regulated alendronate‐gene lipoplex (antagomir@Aln‐Lipo), composed of medicative alendronate‐functionalized liposomal vehicle and encapsulated specific microRNAs is engineered, for bone‐targeting delivery of genes to achieve combined mitigation of bone loss. Alendronate targets hydroxyapatite in the bone matrix and occupies the adhesion site of osteoclasts, thus providing the “physical barriers”. Antagomir is coupled precisely to specific endogenous microRNAs, thus providing the “genetic signals”. These functionalized lipoplexes exhibited long‐term stability and good transfection efficiency. It is proven that antagomir@Aln‐Lipo could synergistically regulate osteoclastogenesis and bone resorption in vitro and in vivo. Furthermore, intravenous injection of antagomir@Aln‐Lipo efficiently reverses bone loss through a dual mechanism driven by alendronate and antagomir‐378a‐3p. In conclusion, the osteophilic and dual‐regulated antagomir@Aln‐Lipo offers a brand‐new bifunctional strategy for the precise treatment of PMOP.
Prodigiosin pigment from Serratia marcescens MBM‐17 from facial acne as antimicrobial agent
Authors: Pallath Nisha , Johnson Sona , Paul Elizabeth , TA Raslana 
Published: July 2023

AbstractA pigment is a naturally occurring colored substance that is created by plants, animals, and microbes. Pigments are utilized in a variety of industries, including food coloring, pharmaceuticals, fabric dying, cosmetics, ink plastics, coloring paints, and so on. The Natural pigments /Bio pigments are very expensive because mass production is difficult. There are more pigments in nature, but only a small number are available in large enough amounts to be useful for industry. This study is attempted to isolate a bacterial red pigmented organism from facial acne was identified as Serratia marcescens MBM‐17 according to Bergey's manual of determinative bacteriology and molecular characterization and production of red pigment was optimized at various growth factors, maximum pigment production was at pH 4, 72 h and 37 ± 2°C, that is, 15.56 g/ L. The partial purified pigment was characterized by UV–Vis, and maximum absorbance was at 533.5 nm. SEM analysis shows that the surface morphology and FTIR spectroscopy revealed the presence of prodigiosin. Prodigiosin has antibacterial efficacy against gram positive bacterial strains, Staphylococcus aureus, Bacillus sp, and gram negative bacterial strains. Klebsiella sp, Pseudomonas sp, Salmonella sp, antifungal potency against Aspergillus niger, Aspergillus flavus, Penicillium sp, Rhizopus sp, and Mucor sp, and checked the fabric dying effects of pigments. Prodigiosin used as fabric dye is applied on clothes, which shows good color tone. This study is highlighting the production of a natural pigment/drug, Prodigiosin with antimicrobial activity may be used for the manufacture of dyed dress materials and masks having antimicrobial action for public especially health workers in this pandemic situation.
At a fine scale, hardwood patches support wildlife diversity in longleaf pine woodlands
Authors: Sovie Adia R. , Conner L. Mike , McCleery Robert A. 
Published: July 2023

AbstractRestoring and maintaining biodiversity in a changing world is increasingly challenging due to the competing needs of species for suitable space and resources. One ecosystem that has seen considerable anthropogenic changes in extent and structure is the longleaf pine (Pinus palustris) ecosystem. Understanding how wildlife responds to restoration is important to informing forest restoration and conservation. We monitored game birds and mid‐large‐sized mammal occupancy in and around hardwood patches embedded within a longleaf pine woodland at The Jones Center at Ichauway in Newton, GA. We found that 11 species use the transition zone between the longleaf pine and hardwood hammocks. Gray squirrels (Sciurus carolinensis), Virginia opossums (Didelphis virginiana), and nine‐banded armadillos (Dasypus novemcinctus) occupancy increased along the gradient while fox squirrel (Sciurus niger) declined. Our results suggest that oak patches and transitional zones are important to maintaining biodiversity within the longleaf pine ecosystem.
Über das Protokoll hinaus. Zum Verhältnis von Kontingenz und algorithmischer Kontrolle im militärisch-polizeilichen Phantasma der Automation
Authors: Franz Nina 
Published: July 2023

ZusammenfassungKontingent ist, was weder notwendig noch unmöglich ist. Dass Akteure immer auch anders kommunizieren und handeln können, gehört zur Grundkondition moderner Gesellschaften – und lässt den Wunsch aufkommen, diese Dimension zu kontrollieren. Ausgehend von der zentralen Rolle, die dem Problem der Kontingenz im Zusammenhang moderner Kriegsführung zukommt, geht es in diesem Beitrag um eine spezielle automatisierte Form dessen, was als »protocological control« beschrieben wurde und im Zusammenhang heutiger Überwachungsregime um den Begriff des „Pan-Protokollarischen“ ergänzt werden kann. Im Zentrum steht dabei das dialektische Verhältnis von Determiniertheit und Offenheit, das in einem neuen technologisch bedingten Verhältnis von Kontrolle und Kontingenz wieder zu Tage tritt.
Fiktion, Archiv, Funktion. Über Die Protokolle der Weisen von Zion
Authors: Penke Niels 
Published: July 2023

ZusammenfassungDieser Beitrag unternimmt es, den Protokoll-Begriff für die Protokolle der Weisen von Zion auf drei Ebenen zu verfolgen. Zunächst geht es darum, wie Protokolle in ihren historischen Rückbezügen funktionieren: Sie stellen als Ergebnisprotokoll fest, was der Antisemitismus über sein Feindbild, dessen Wesen, Geschichte und Interessen ‚weiß‘. Durch diesen archivalischen Charakter, der es ermöglicht, bei Bedarf hervorgeholt zu werden, um Anklage, Beweisführung und Maßnahmen gleichermaßen zu begründen, wirken die Protokolle zweitens auch funktional als Protokoll: Sie werden als Protokolle rezipiert und verarbeitet. Die dritte Ebene der Untersuchung zielt auf eine (psychologisierende) Erklärung dieser Wirksamkeit, da sich für den Antisemitismus in der Form des Protokolls die Rationalität des bürokratischen und kapitalistischen ‚jüdischen‘ Geistes selbst beweist, den das Ressentiment als typisch annimmt.
›Prot. auf.‹ Kafkas Mitschriften der Bürokratie
Authors: Wolf Burkhardt 
Published: July 2023

ZusammenfassungAls Form und Medium steht das Protokoll am Anfang und am Ende von Franz Kafkas Schreiben. Die maßgeblichen Verfahren und Themen seiner Romane wurden nämlich weniger in seiner angeblich ersten gelungenen Erzählung (dem »Urteil« von 1912) erprobt als vielmehr in seiner (bereits 1911 entstandenen) Mitschrift zum Ereignis und zur Abwicklung eines Verkehrsunfalls. Dieser proto-literarische und proto-protokollarische Text ist eine Art sprachexperimentelles Verlaufsprotokoll, das den Prozess und das Procedere des behördlichen Protokollierens ebenso erfasst wie jene protokollarische Ordnung, die die soziale Beobachtung, Beurteilung und Bewältigung eines öffentlichen Vorfalls, eines Versicherungsfalls oder Verwaltungsvorgangs vorschreibt. Kafkas späte Erzähltexte werden diesen ‚bürokratischen‘ Horizont dann überschreiten: Sie beschränken sich nicht auf die Szenarien des ‚Institutionenromans‘ (Rüdiger Campe), sondern eröffnen auch erste Perspektiven auf die postbürokratische oder ‚panprotokollarische‘ Kontrollgesellschaft von heute. Denn was hier die Verflechtung von Amts- und Lebenswelt zu unüberschaubaren Netzwerken besorgt, sind nicht mehr nur aktenförmige Mitschriften – es sind vielmehr mediale Protokolle im Sinne soziotechnischer protocols.
Administrativ-politische und editorisch-technische Protokolle. Der cisleithanische Ministerrat 1848–1918
Authors: Kurz Stephan 
Published: July 2023

ZusammenfassungDer Beitrag stellt vor, wie die Verwaltung der Habsburgermonarchie und später Cisleithaniens die Protokolle ihrer Ministerratssitzungen führte, wie diese Protokolle überliefert wurden und was die aktuellen Herausforderungen dabei sind, die seit den 1970er Jahren bearbeitete wissenschaftliche Edition der im österreichischen Staatsarchiv bewahrten Dokumente in eine online und gedruckt erscheinende hybride Edition nach den Regeln der Kunst zu überführen. Dabei werden insbesondere die Anforderungen digitaler Edition von Protokollen und zugehörigen Metadaten nach den Vorschlägen der Text Encoding Initiative (TEI) thematisiert, vor allem dort, wo die Edition aufgrund des Justizpalastbrandes von 1927 mit einem überaus löchrigen Bestand und notwendigen Ergänzungen aus anderen Archivbeständen umzugehen hat. Für die Protokollforschung bietet der Beitrag Einblicke in ein 60 Jahre umfassendes und frei verfügbares Korpus an vormals geheimen Regierungsprotokollen und deren Praxis bei der Erfassung, Ordnung und Überlieferung gouvernementalen Wissens, darüber hinaus aber auch in die Daten- und Workflowmodellierung bei dessen Transmission mithilfe aktueller Erschließungs- und Publikationstechnologien.
Interpretation of SLC3A1 and SLC7A9 variants in cystinuria patients: The significance of the PM3 criterion and protein stability
Authors: Lee Beomki , Lee Soo-Youn , Han Deok Hyun , Park Hyung-Doo 
Published: July 2023

AbstractCystinuria is a genetic disorder caused by defects in the b0,+ transporter system, which is composed of rBAT and b0,+AT coded by SLC3A1 and SLC7A9, respectively. Variants in SLC3A1 and SLC7A9 follow autosomal recessive inheritance and autosomal dominant inheritance with reduced penetrance, respectively, which complicates the interpretation of cystinuria-related variants. Here, we report seven different SLC3A1 variants and six different SLC7A9 variants. Among these variants were two novel variants previously not reported: SLC3A1 c.223C > T and SLC7A9 c.404A > G. In silico analysis using REVEL correlated well with the functional loss upon SLC7A9 variants with scores of 0.8560–0.9200 and 0.4970–0.5239 for severe and mild decrease in transport activity, respectively. In addition, DynaMut2 was able to predict a decreased protein expression level resulting from the SLC7A9 variant c.313G > A with a ΔΔGStability −2.93 kcal/mol. Our study adds to the literature as additional cases of a variant allow applying the PM3
criterion with higher strength level. In addition, we suggest the clinical utility of REVEL and DynaMut2 in interpreting SLC3A1 and SLC7A9 variants. While a decreased protein expression level is not embraced in the current variant interpretation guidelines, we believe in silico protein stability predicting tools could serve as evidence of protein function loss.
Combined effects of green tea supplementation and eccentric exercise on nuclear factor erythroid 2-related factor 2 activity
Authors: Thorley Josh , Thomas Craig , Thon Nicolas , Nuttall Hannah , Martin Neil R. W. , Bishop Nicolette , Bailey Stephen J. , Clifford Tom 
Published: July 2023

Abstract
Purpose
This study investigated whether combining eccentric exercise and green tea supplementation synergistically increased nuclear factor erythroid 2-related factor 2 (NRF2) activity, a transcription factor responsible for coordinating endogenous antioxidant expression.

Methods
In a double-blinded, randomized, between-subjects design, 24 males (mean [SD]; 23 [3] years, 179.6 [6.1] cm, 78.8 [10.6] kg) performed 100 drop jumps following a 6 days supplementation period with either green tea (poly)phenols (n = 12; 500 mg·d−1) or a placebo (n = 12; inulin). NRF2/antioxidant response element (ARE) binding in peripheral blood mononuclear cells (PBMCs), catalase (CAT) and glutathione reductase (GR) activity, 8-hydroxy-2′-deoxyguanosine (8-OHdG) excretion, and differential leukocyte counts were measured pre-, post-, 1 h and 24 h post-exercise.

Results
Exercise did not increase NRF2/ARE binding (p = 0.12) (fold change vs rest: green tea = [post] 0.78 ± 0.45, [1 h] 1.17 ± 0.54, [24 h] 1.06 ± 0.56; placebo = [post] 1.40 ± 1.50, [1 h] 2.98 ± 3.70, [24 h] 1.04 ± 0.45). Furthermore, CAT activity (p = 0.12) and 8-OHdG excretion (p = 0.42) were unchanged in response to exercise and were not augmented by green tea supplementation (p > 0.05 for all). Exercise increased GR activity by 30% (p = 0.01), however no differences were found between supplement groups (p = 0.51). Leukocyte and neutrophil concentrations were only elevated post-exercise (p < 0.001 for all).

Conclusion
Eccentric exercise, either performed alone or in conjunction with green tea supplementation, did not significantly increase NRF2 activity in PBMCs.

Trial registration number
osf.io/kz37g (registered: 15/09/21).

Graphical abstract
Comparison of data-driven methods for linking extreme precipitation events to local and large-scale meteorological variables
Authors: Antoniadou Nafsika , Sørup Hjalte Jomo Danielsen , Pedersen Jonas Wied , Gregersen Ida Bülow , Schmith Torben , Arnbjerg-Nielsen Karsten 
Published: July 2023

AbstractExtreme precipitation events can lead to severe negative consequences for society, the economy, and the environment. It is therefore crucial to understand when such events occur. In the literature, there are a vast number of methods for analyzing their connection to meteorological drivers. However, there has been recent interest in using machine learning methods instead of classic statistical models. While a few studies in climate research have compared the performance of these two approaches, their conclusions are inconsistent. To determine whether an extreme event occurred locally, we trained models using logistic regression and three commonly used supervised machine learning algorithms tailored for discrete outcomes: random forests, neural networks, and support vector machines. We used five explanatory variables (geopotential height at 500 hPa, convective available potential energy, total column water, sea surface temperature, and air surface temperature) from ERA5, and local data from the Danish Meteorological Institute. During the variable selection process, we found that convective available potential energy has the strongest relationship with extreme events. Our results showed that logistic regression performs similarly to more complex machine learning algorithms regarding discrimination as measured by the area under the receiver operating characteristic curve (ROC AUC) and other performance metrics specialized for unbalanced datasets. Specifically, the ROC AUC for logistic regression was 0.86, while the best-performing machine learning algorithm achieved a ROC AUC of 0.87. This study emphasizes the value of comparing machine learning and classical regression modeling, especially when employing a limited set of well-established explanatory variables.
Life histories of poeciliid fishes: searching for a size-dependent trade-off between number and size of offspring
Authors: Zúñiga-Vega J. Jaime , Olivera-Tlahuel Claudia , Saleh-Subaie Nabila , Suárez-Rodríguez Monserrat 
Published: July 2023

AbstractA large body of knowledge about life-history traits has arisen from research on viviparous fishes of the family Poeciliidae. Still, the wide variation among species in reproductive strategies provides an excellent opportunity to further explore how life-history traits covary and the causes of covariation patterns. In this study, we provide information on brood size, offspring mass at birth, and total reproductive allotment of six poeciliid species (Gambusia sexradiata, Poeciliopsis latidens, Poeciliopsis viriosa, Priapella intermedia, Pseudoxiphophorus jonesii, and Xiphophorus hellerii). Also, we searched for a trade-off between the number of offspring that females produce and the size of each individual offspring. We tested the hypothesis that this trade-off should be stronger in small females because of the space constraints in the reproductive tract that are inherent to a small body size. If this hypothesis were correct, we expected a strong negative relationship between number and size of offspring in small females and a weaker or undetectable relationship between these two life-history traits in larger females. We found evidence of such a size-dependent trade-off in only one species. Small females of Po. latidens that produced relatively large broods experienced the cost of a reduction in the average size of each offspring. In larger females this negative relationship was weaker. Unexpectedly, we found no evidence of this trade-off in the other five poeciliid species and, in contrast, in one species (Priapella intermedia) females that produced numerous embryos were also capable of producing relatively large embryos. We discuss potential explanations for the different patterns of covariation (or lack of covariation) between number and size of offspring that we detected in these viviparous species.
Latent feature reconstruction for unsupervised anomaly detection
Authors: Lin Jinghuang , He Yifan , Xu Weixia , Guan Jihong , Zhang Ji , Zhou Shuigeng 
Published: July 2023

AbstractAnomalies (or outliers) indicate a minority of data items that are quite different from the majority (inliers) of a dataset in a certain aspect. Unsupervised anomaly detection (UAD) is an important but not yet extensively studied research topic. Recent deep learning based methods exploit the reconstruction gap between inliers and outliers to discriminate them. However, it is observed that the reconstruction gap often decreases rapidly as the training process goes. And there is no reasonable way to set the training stop point. To support effective UAD, we propose a new UAD framework by introducing a Latent Feature Reconstruction (LFR) layer that can be applied to recent UAD methods. The LFR layer acts as a regularizer to constrain the latent features in a low-rank subspace from which inliers can be reconstructed well while outliers cannot. We develop two new UAD methods by implementing the proposed framework with autoencoder architecture and geometric transformation scheme. Experiments on five benchmarks show that our proposed methods can achieve state-of-the-art performance in most cases.
A Research-Informed Approach to Providing Behavioral Healthcare to Women with Extensive Trauma Histories
Authors: Greene Alison , Korchmaros Josephine D. 
Published: July 2023

AbstractTranslating research to behavioral healthcare practice is vital for improving treatment impact but can be challenging. Current and lifetime histories of trauma need to be considered in behavioral healthcare provision as they can significantly affect an individual’s treatment experience. This article provides guidance on how to utilize research findings regarding trauma prevalence and experiences of women who have substance use disorder and who are homeless or near homeless to help guide responsive healthcare and treatment in practice.
Teacher Expectations and Self-Determination Theory: Considering Convergence and Divergence of Theories
Authors: Hornstra Lisette , Stroet Kim , Rubie-Davies Christine , Flint Annaline 
Published: July 2023

Abstract Various theories from the field of educational psychology, including high expectation theory (HET) and self-determination theory (SDT), focus on the classroom conditions which facilitate students’ motivation, learning, and well-being. In the current paper, we aimed to breech the theoretical division between HET and SDT through a synthesis of both theories. We identified multiple areas of convergence and complementarity. The teaching practices that are theorized to support students’ motivation, learning, and well-being put forward by both HET and SDT show a high degree of conceptual overlap. Moreover, findings from both research fields suggest a gap between theory and practice: although the teaching principles put forward by both theories are believed to be effective for all students, not all teachers optimally apply these principles in their teaching or apply them equally for all classes or all students. Both theories acknowledge that teacher beliefs and contextual factors may account for this gap between theory and practice. In the paper, we put forward an integrative model to show how the two theories converge and complement each other. The integration of the two theories offers a way forward in terms of understanding and applying these two theoretical stances to the classroom.
A longitudinal study of relations among apprentices’ nonwork orientation, decent work, and job satisfaction
Authors: Zambelli Camilla , Rossier Jérôme , Marcionetti Jenny 
Published: July 2023

AbstractThe type of nonwork orientation and decent work perception are supposed to be important factors that influence well-being at work. In this study, 196 Swiss apprentices enrolled in a vocational education training were assessed twice during the first 24 months of their apprenticeship. The results showed that there are specific links between nonwork orientations, decent work, and job satisfaction over time. Concerning relations among decent work dimensions, the results highlighted the importance of safe working conditions to predict complementary values perception and the importance of this in predicting adequate compensation perception. Implications for practice are discussed.