bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional gradient perturbation in Wilson disease correlates with structural lesions and transcriptomic specializations
Authors: Hu Sheng , Li Chuanfu , Wang Yanming , Wei Taohua , Wang Xiaoxiao , Dong Ting , Yang Yulong , Ding Yufeng , Qiu Bensheng , Yang Wenming 
Published: June 2023

AbstractFunctional dysregulations in multiple regions are caused by excessive copper deposition in the brain for Wilson disease (WD). While the biological mechanism of these dysregulations was thought to be the absent or reduced expression of the ATP7B protein in the liver, mechanisms for such gene impacting brain function remain unexplored. Here, we used a large cohort of resting-state fMRI data (105 WD patients and 93 healthy controls) to derive the functional connectome gradient, and its WD-related alterations were further evaluated. Then, we used Neurosynth, clinical data, and whole-brain gene expression to examine the meta-analytic cognitive function, clinical phenotypes, and transcriptional specializations related to WD gradient alterations. In parallel, spatial correlation between gradient and gray matter volume was accessed for both WD patients and healthy controls. Compared to controls, WD patients exhibited principal gradient alterations in both global and system levels and regional alterations mainly distributed in the sensorimotor, visual, ventral attention, subcortical, and default mode networks. Meta-analytic terms and clinical characters showed the correlations of these gradient alterations in motor-related processing, higher-order cognition, neurological symptom, and age. Results of spatial correlation revealed structure-function decoupling in multiple networks, especially in subcortical and visual networks. Within the cortex, the gradient alterations derived transcriptional specializations of WD that mainly display properties indicative of ion homeostasis, neural development, and motor controls. Within the subcortical regions, we for the first time characterized the role of the ATP7B gene impacting subcortical function. Transcriptional specializations of WD within both cortex and subcortical regions were also associated with neurological and psychiatric disorders, explaining the mechanism underlying complex clinical symptoms from the biological level for WD. In addition, we further illustrated that structural lesion and gradient perturbation shared similar transcriptional specializations in both cortex and subcortical regions for WD. These findings bridged functional gradient perturbation to structural lesions and transcriptional profiles in WD, possibly promoting our understanding of the neurobiological underpinnings underlying the emergence of complex neurological and psychiatric phenotypes.
Genetic analysis of 42 Y-STR loci in Han and Manchu populations from the three northeastern provinces in China
Authors: Song Wenqian , Zhou Shihang , Yu Weijian , Fan Yaxin , Liang Xiaohua 
Published: June 2023

AbstractBackgroundY-STR polymorphisms are useful in tracing genealogy and understanding human origins and migration history. This study aimed to fill a knowledge gap in the genetic diversity, structure, and haplogroup distribution of the Han and Manchu populations from the three northeastern provinces in China (Liaoning, Jilin, and Heilongjiang).MethodsA total of 1,048 blood samples were collected from unrelated males residing in Dalian. Genotyping was performed using the AGCU Y37+5 Amplification Kit, and the genotype data were analyzed to determine allele and haplotype frequencies, genetic and haplotype diversity, discrimination capacity, and haplotype match probability. Population pairwise genetic distances (Fst) were calculated to compare the genetic relationships among Han and Manchu populations from Northeast China and other 36 populations using 27 Yfiler Plus loci set. Multi-dimensional scaling and phylogenetic analysis were employed to visualize the genetic relationships among the 40 populations. Moreover, haplogroups were predicted based on 27 Yfiler Plus loci set.ResultsThe Han populations from Northeast China exhibited genetic affinities with both Han populations from the Central Plain and the Sichuan Qiang population, despite considerable geographical distances. Conversely, the Manchu population displayed a relatively large genetic distance from other populations. The haplogroup analysis revealed the prevalence of haplogroups E1b1b, O2, O3, and Q in the studied populations, with variations observed among different ethnic groups.ConclusionThe study contributes to our understanding of genetic diversity and history of the Han and Manchu populations in Northeast China, the genetic relationships between populations, and the intricate processes of migration, intermarriage, and cultural integration that have shaped the region’s genetic landscape.
The effect of a visual arts and exercise program on communication and social skills of students with autism spectrum disorders
Authors: Broupi Alexandra Eleftheria , Kokaridas Dimitrios , Tsimaras Vasileios , Varsamis Panagiotis 
Published: June 2023

Purpose
Individuals with autism spectrum disorders (ASD) present challenges in their social and communication skills such as difficulties in developing interpersonal relationships and verbal and nonverbal communication; repetitive and restricted behaviors concerning resistance to environmental change, stereotyped movements and unusual reactions to sensory stimuli; and significant delays in motor development and performance. The purpose of this study was to investigate the effect of a combined visual arts and exercise program on the communication and social behavior skills of people with ASD.

Design/methodology/approach
The research was conducted in a Creative Employment Center of People with Disabilities, and the sample consisted of 18 participants with ASD divided randomly into a control group (CG) (n = 8) and an experiment group (EG) (n = 10). The Social Communication Questionnaire (SCQ) was used prior and after the implementation of the intervention program. EG participants attended an intervention program, whereas CG individuals followed their daily routine activities, and they only completed the SCQ prior and after the program.

Findings
EG demonstrated statically significant improvements in communication skills and social behavior, compared to the results of the CG. Furthermore, participants with Asperger’s syndrome showed a higher improvement rate compared to participants with autism, while no statistically significant differences were noticed concerning gender and age of the participants.

Originality/value
To the best of the authors’ knowledge, this is the first paper to investigate the effect of a combined visual arts and adapted physical activity program on the social and communication skills of people with ASD.
A partial solution for the replication crisis in economics
Authors: Briggs William M. 
Published: June 2023

PurposeImportant research once thought unassailable has failed to replicate. Not just in economics, but in all science. The problem is therefore not in dispute nor are some of the causes, like low power, selective reporting, the file drawer effect, publicly unavailable data and so forth. Some partially worthy solutions have already been offered, like pre-registering hypotheses and data analysis plans.Design/methodology/approachThis is a review paper on the replication crisis, which is by now very well known.FindingsThis study offers another partial solution, which is to remind researchers that correlation does not logically imply causation. The effect of this reminder is to eschew “significance” testing, whether in frequentist or Bayesian form (like Bayes factors) and to report models in predictive form, so that anybody can check the veracity of any model. In effect, all papers could undergo replication testing.Originality/value The author argues that this, or any solution, will never eliminate all errors.
How business process management culture supports digital innovation: a quantitative assessment
Authors: Distel Bettina , Plattfaut Ralf , Kregel Ingo 
Published: June 2023

PurposeCurrent research suggests culture as a driving force of successful digital innovation (DI) that may not only built an organization's capability to digitally innovate but also reduce impeding factors within the organization. Only few empirical accounts support this hypothesis so far. Details of how culture supports DI are yet under-researched. This article aims to investigate the relationship between culture, organizational DI capabilities and DI barriers.Design/methodology/approachThe authors address this issue by using survey data from German municipalities (n = 668), build a structural equation model (SEM) and analyze data using partial least squares SEM.FindingsResults indicate that the business process management (BPM) culture dimensions continuous improvement and process innovation support DI capabilities. Barriers exist that partially mediate the impact of culture on capabilities.Originality/valueThe results of this study show that BPM culture is not a uniform construct and that its dimensions have both positive and negative impact on the building of organizational digitalization capabilities.
Customer experience in five-star hotel businesses: is it an “experience” for customers?
Authors: Şanlıöz-Özgen H. Kader , Kozak Metin 
Published: June 2023

PurposeConcerning the development of “experience” as an economic phenomenon, this study aims to analyse customers' evaluations of their experiences in five-star hotel businesses and to identify if the hospitality experience is evaluated as an “experience” by its specific aspects.Design/methodology/approachStructural and thematic narrative analyses in a multi-dimensional setting were applied to stories from 107 participants who stayed in five-star hotel businesses.FindingsCustomers evaluate their overall experience as an “experience” reflected by experiential statements. However, they demonstrate higher cognitive orientation at the sub-experience levels (food and beverage, rooms, etc.).Research limitations/implicationsThe paper sheds light on the fact that customers may evaluate their experiences with cognitive and experiential aspects. The study focuses on participants' lived experiences to understand the customer perspective with the “experience” concept leading to the memorability of customer experiences in hotel businesses. Further research is required with a larger sample group, mixed-methods implementation and longitudinal and comparable examination to understand seasonal, motivational and cultural differences.Practical implicationsThe paper reveals various aspects of customer experiences in five-star hotel businesses around the variety of their offerings evaluated by cognitive and experiential perceptions so that dedicated efforts of the managers will be enhanced with a better and strategic understanding of the “experience” concept to achieve business goals.Originality/valueThe study offers insightful findings relating to customers’ service- and experience-based experiences and how “experience” is perceived by customers from various angles in the five-star hotel businesses.
Enhancing effectiveness of online training program through assessment of participant engagement index
Authors: Wavre Shrikant Prabhakar , Kuknor Sunaina 
Published: June 2023

Purpose
This study focuses on the identification of key attributes to measure participant engagement in an online training program (OTP) to improve training effectiveness through active and positive learning engagement with learners learning ownership.

Design/methodology/approach
As a qualitative study, 18 semi-structured interviews were conducted with corporate and L&D (learning and development) experts from multinational companies operating in India. The interviews were transcribed, and the data was analyzed using content analysis. One focused group discussion was conducted for validity.

Findings
The study found six factors for developing the participant engagement index (EI) namely, 1. Quality of questions, 2. Attention to details, 3. Quality of output during training activities, 4. Connecting to practical examples, 5. Professional approach (adhering to guidelines), 6. Team dynamics. Each identified attribute pertaining to these factors was further validated into cognitive, behavioral, and emotional engagement components forming a part of the EI.

Practical implications
This study provides insights for HRD managers, functional managers, L&D experts, and participants to leverage engagement measurement attributes for collaborative learning in OTP for effective learner ownership and learning outcomes. Further, this study will assist trainers to focus and prioritize their efforts to increase participant involvement and engagement in OTP.

Originality/value
It contributes to the growing field of virtual training for enhancing learning engagement, learning enhancement, and learner accountability. The author's contribution to this study is to evaluate the key attributes of the participant’s EI for meeting training goals, which is unique to the study
The nail in the coffin? Pandemic and social dialogue in Poland
Authors: Czarzasty Jan , Mrozowicki Adam 
Published: June 2023

PurposeIn the context of debates on the role of social partners in shaping anti-crisis policies, the article explores the developments of social dialogue in Poland following the outbreak of the pandemic. The central research question is whether the crisis has helped to revitalise social dialogue or has it further revealed its weaknesses that were apparent before it.Design/methodology/approachThe paper is based on the combination of literature review and the analysis of primary data derived from 22 expert interviews with the representatives of trade unions, employers and ministries collected in 2020–2021 in four essential industries (education, health care, social care and logistics).FindingsThe analysis suggests that the pandemic led to reinforcement of “illusory corporatism” in Poland, deepened mistrust among social partners and triggered a shift to informal channels of influencing policymaking. The weakness of the social partners and the strong position of the right-wing populist government meant that fears of recession and a health crisis were insufficient to develop “crisis” corporatism. While business interests were represented better than labour in policymaking, limited labour-friendly outcomes have been achieved as a result of workers’ mobilisation and unilateral decisions of the government rather than tripartite social dialogue.Originality/valueBased on original empirical research, the article contributes to the discussion on the impact of the crisis on social dialogue under patchwork capitalism. It points to the role of strong governments and informality in circumventing tripartite structures and the importance of essential workers’ mobilisation in response to the lack of social dialogue.
When causal attribution meets cuisine type: how consumer power and moral identity moderate virtual kitchen patronage
Authors: Leung Xi Yu , Cai Ruiying , Zhang Huiying , Bai Billy 
Published: June 2023

Purpose
Virtual kitchens are a new business phenomenon, and how customers react to the new business model is still a largely unexplored topic. The purpose of this study is to examine the underlying mechanisms of consumers’ different responses to their reasoning of the new and disruptive business model of the virtual kitchen.

Design/methodology/approach
Based on the attribution theory and situated focus theory of power, this study conducts three online experiments to test the proposed framework. A total of 487 US residents who had prior experience with restaurant food delivery participated in the studies.

Findings
The results indicate that external attribution (vs internal attribution) and ethnic cuisine (vs mainstream cuisine) are more likely to elicit customers’ empathy and justice, leading to higher purchase intentions with virtual kitchens. A mainstream virtual kitchen is better off attributing itself to external factors. The significant effects of causal attribution and cuisine type on purchase intention only exist with powerful customers and those with high moral identity.

Research limitations/implications
The results of this study provide valuable insight to virtual kitchen businesses to better position and market themselves to gain customers’ support. The findings also suggest that ethnic and mainstream restaurants should strategize their marketing communications about virtual kitchens differently.

Originality/value
To the best of the authors’ knowledge, this study is one of the first to provide in-depth insight into the growing phenomenon of virtual kitchens. It also contributes to the extant literature on attribution theory and situated focus theory of power.
Characteristics of crises resilient organizations in the hospitality and tourism industry
Authors: Aydogan Merve , de Esteban Curiel Javier , Antonovica Arta , Cetin Gurel 
Published: June 2023

Purpose
COVID-19, like many previous crises, proved once more that some hospitality and tourism organizations are more crises resilient than others. Despite increasing frequency and magnitude of crises, little is known about the features of crises resilient organizations and mitigation strategies they adopt. If the characteristics of such resiliency are identified, those strengths might be targeted. Hence, the purpose of this study is to identify characteristics of crises resilient organizations by analyzing the interface between different organizational characteristics, recovery strategies they adopted and impacts of COVID-19 on individual hospitality and tourism organizations.

Design/methodology/approach
A global sample of 202 respondents from 20 countries and four continents, representing different sectors of the hospitality and tourism industry, participated in the survey. Descriptive analysis and cluster analysis were used to rank the items and group hospitality and tourism organizations based on their crises resiliency.

Findings
Service quality, loyal customers, branding, high paid in capital, domestic market base, hygiene and safety image, information and communication technology adoption, product and market diversification and restructuring debts emerged as major characteristics and strategies of crises resilient organizations. Using cluster analysis, four different groups of organizations were identified. Based on the impacts of COVID-19 on these organizations, Cluster-1 emerged as significantly more crises resilient, whereas Cluster-4 organizations were significantly more vulnerable to crises. Their characteristics and mitigation strategies they adopted were discussed.

Research limitations/implications
The paper not only identified features of crises resilient organizations and successful mitigation strategies but also measured their impact on various performance indicators. Future studies might use characteristics, mitigation strategies and performance indicators identified in this study.

Practical implications
Based on the findings, tourism organizations would focus on strengthening characteristics and implementing strategies that make crises resilient organizations. Public bodies and destination management would also set their decision criteria based on these findings to create a more resilient tourism industry.

Originality/value
This research not only identifies how hospitality and tourism organizations are affected by COVID-19 but also how these impacts change based on different organizational characteristics and strategies. Understanding which organizational characteristics affect the crises vulnerability of hospitality and tourism organizations might inform risk and crises management literature and structural design elements in tourism businesses, hence offer both theoretical and practical implications.
Research on parametric design of men's suit lapel based on knowledge
Authors: Lin Kai , Liu Kaixuan 
Published: June 2023

PurposeThe purpose of this paper is to improve the efficiency of pattern-making for suit lapels in the apparel industry, to master the perceptual knowledge of suit lapels and to establish a mapping relationship between suit lapel styles and perceptual judgment.Design/methodology/approachIn this paper, notch lapel, peak lapel and shawl lapel are studied, and the authors extract the structural features in the order of drafting as the input values for model training. At the same time, after the expert screening, four perceptual evaluation dimensions based on a priori knowledge are selected as output values, which are finally classified using a decision tree algorithm.FindingsThe results show that different design parameters produce different perceptions of people's vision and, thus, different perceptual judgments. The decision tree model can effectively classify the perceptual judgment of the lapel shape.Originality/valueThe findings of this study help garment factories to provide optimal judgment of basic parameters before the production of a suit lapel and to improve the efficiency of the design.
Managing Norwegian public libraries as civil public spheres: recent controversies
Authors: Larsen Håkon 
Published: June 2023

PurposeThis paper contains a theoretically inspired discussion of recent Norwegian controversies related to the management of public library space as a civil public sphere.Design/methodology/approachThis study engages with theories of civil public spheres and their application within a Nordic context. The theories are applied in discussions of recent controversies related to the management of Norwegian public libraries as civil public spheres, as represented in professional journals and press articles.FindingsThrough the discussion, it becomes apparent that the value of neutrality and librarians' inclusive practices on the part of societal minorities might be conflicting when managing public libraries as civil public spheres.Originality/valueThis paper engages with recent library controversies in Norway and discusses them in light of recent scholarly work on library activism in a Nordic context, as well as recent theorizations of civil public spheres in the Nordic countries. It thus connects ongoing discussions among Norwegian librarians with recent library research and ongoing theorization of civil public spheres within the Nordic model.
Why do consumers leave fast fashion stores? Role of shoppers' confusion
Authors: Hwang Joohye , Tung Tracie , Cho Hira 
Published: June 2023

PurposeThe study aims to examine fast fashion consumers' negative in-store experiences focusing on the effect of the two store environment factors, product overload and store ambiance, on their confusion and consequent shopping avoidance behavior.Design/methodology/approachA research model of fast fashion consumers' confusion and store avoidance behavior is proposed using the Stimulus–Organism–Response framework. A pretest and the main online survey with 281 samples are analyzed, and the structural equation modeling (SEM) is conducted to test the proposed model.FindingsThe SEM results support the proposed paths statistically. Consumers' confusion, measured with the two dimensions, inefficiency and helplessness, is significantly influenced by their perceived product overload and negative perception of store ambiance in the fast fashion shopping environment. Subsequently, fast fashion consumers' confusion results in less time spent in the store.Originality/valueThe study sheds light on utilitarian shopping value in the fast fashion shopping environment by focusing on the fast fashion consumers' confusion in association with overloaded information caused by too many products and store ambiance.Research limitations/implicationsThe study implies that improving fast fashion stores' inherent issues with too many products and store ambiance might help consumers mitigate their confusion and prevent customer attrition. However, the study includes only two factors. Future studies may include other various fast fashion store factors. Additionally, one of the dimensions of confusion, irritation, did not emerge in this study. More work is needed to investigate fast fashion consumers' confusion, such as using a multigroup analysis by age.