bluuebunny/crossref_metadata_2025_split huggingface dataset:
Problem-based learning using e-module: Does it effect on student’s high order thinking and learning interest in studying geography?
Authors: Wijayanto Bayu , Sumarmi Sumarmi , Hari Utomo Dwiyono , Handoyo Budi , Aliman Muhammad 
Published: June 2023

High Order Thinking Skills (HOTS) are abilities that students in the 21st century must acquire. Problem-based learning is one of the learning models to improve high order thinking skills. E-module is an innovative teaching tools used in geography education. Geography is the main focus of education in the 21st century, especially related to environmental issues. This study aimed to determine the effect of PBL with e-module based on HOTS to student’s learning interest in studying geography. The research population consisted of second-year students (grade 11) of social class in SMAN 2 Semarang (Public Senior High School). This research used a factorial experimental design. The data was collected using a test measuring HOTS and a questionnaire measuring enthusiasm for learning geography. The data were analysed using statistics, including the normality test, the homogeneity test, and hypothesis testing with the T-test, linear regression, and two-way ANOVA. The results found that: 1) PBL with e-modules had a significant effect on HOTS; 2) student’s interest in studying geography had no significant effect on HOTS; 3) there was no effect between PBL and e-modules with student’s interest in studying geography on HOTS. The HOTS test results were unaffected by the increase or decrease in student’s interest. The HOTS is not influenced by student’s interest in studying geography, but rather by the actual learning; 4) the highest indicator of developing HOTS is the capacity for abstract thought; 5) students conclude that using e-modules in PBL can improve interest for solving environmental issues. The combination of e-module content with project-based learning motivates students to protect the environment.
The Complement-Targeted Inhibitor Mini-FH Protects against Experimental Periodontitis via Both C3-Dependent and C3-Independent Mechanisms
Authors: Li Xiaofei , Wang Hui , Schmidt Christoph Q , Ferreira Viviana P , Yancopoulou Despina , Mastellos Dimitrios C , Lambris John D , Hajishengallis George 
Published: June 2023

Abstract
A minimized version of complement factor H (FH), designated mini-FH, was previously engineered combining the N-terminal regulatory domains (short consensus repeat [SCR]1–4) and C-terminal host-surface recognition domains (SCR19–20) of the parent molecule. Mini-FH conferred enhanced protection, as compared with FH, in an ex vivo model of paroxysmal nocturnal hemoglobinuria driven by alternative pathway dysregulation. In the current study, we tested whether and how mini-FH could block another complement-mediated disease, namely periodontitis. In a mouse model of ligature-induced periodontitis (LIP), mini-FH inhibited periodontal inflammation and bone loss in wild-type mice. Although LIP-subjected C3-deficient mice are protected relative to wild-type littermates and exhibit only modest bone loss, mini-FH strikingly inhibited bone loss even in C3-deficient mice. However, mini-FH failed to inhibit ligature-induced bone loss in mice doubly deficient in C3 and CD11b. These findings indicate that mini-FH can inhibit experimental periodontitis even in a manner that is independent of its complement regulatory activity and is mediated by complement receptor 3 (CD11b/CD18). Consistent with this notion, a complement receptor 3–interacting recombinant FH segment that lacks complement regulatory activity (specifically encompassing SCRs 19 and 20; FH19–20) was also able to suppress bone loss in LIP-subjected C3-deficient mice. In conclusion, mini-FH appears to be a promising candidate therapeutic for periodontitis by virtue of its ability to suppress bone loss via mechanisms that both include and go beyond its complement regulatory activity.
Do Serum Adiponectin Levels Correlate with the Severity of Acne: A Cross-sectional Analysis
Authors: Aggarwal Shivali , Batra Jayati , Singla Aanchal , Gupta Sharang , Chopra Preeyati , Chopra Dimple 
Published: June 2023

Background: Acne vulgaris is a common disorder of pilosebaceous units affecting adolescents and young adults. The various causes include diet, stress, seborrhea, and premenstrual flare. Objective: The objective of this study was to compare lipid profile, insulin, and adiponectin levels in acne and controls. Materials and Methods: Sixty patients of acne from the age group of 12 to 25 years and 20 healthy age- and gender-matched controls were included in the study. Results: Patients with acne showed significantly higher levels of total cholesterol and low-density lipoprotein (LDL), higher levels (although not statistically significant) of triglyceride, and very LDL and significantly lower levels of high-density lipoprotein as compared to controls. Furthermore, individuals with acne had significantly lower levels of serum adiponectin and significantly higher mean levels of fasting serum insulin as compared to controls. Conclusion: Derangements in serum lipid profile, serum insulin, and serum adiponectin levels can predispose to acne in adolescent individuals. Thus, dietary and lifestyle modifications should be recommended in such patients.
Capacity Building in Pediatric Critical Care-Global Health Research and Education: The Blantyre Experience
Authors: Raees Madiha Q. , Chimalizeni Yamikani , Liomba Alice W. Muiruri , Pensulo Paul , Gushu Montfort Benard , Tebulo Andrew , Malenga Albert , Sikorski Michael J. , Holloway Adrian J. , Bhutta Adnan T. , Doctor Allan , Remy Kenneth E. , O’Brien Nicole F. , Postels Douglas G. , Taylor Terrie E. 
Published: June 2023

ABSTRACT.
Pediatric critical care medicine (PCCM), as it is practiced in high-income countries, is focused on specialized medical care for the most vulnerable pediatric patient populations. However, best practices for provision of that care globally are lacking. Thus, PCCM research and education programming can potentially fill significant knowledge gaps by facilitating the development of evidence-based clinical guidelines that reduce child mortality on a global scale. Malaria remains a leading cause of pediatric mortality worldwide. The Blantyre Malaria Project (BMP) is a research and clinical care collaborative that has focused on reducing the public health burden of pediatric cerebral malaria in Malawi since 1986. In 2017, the requirements of a new research study led to the creation of PCCM services in Blantyre, creating the opportunity to establish a PCCM-Global Health Research Fellowship by BMP in collaboration with the University of Maryland School of Medicine. In this perspective piece, we reflect on the evolution of the PCCM-Global Health research fellowship. Although the specifics of this fellowship are out of the scope of this perspective, we discuss the context allowing for the development of this program and explore some early lessons learned to consider for future capacity-building efforts in the future of PCCM-Global Health research.
STUDY OF THE LEVEL OF STRESS AND DEPRESSION AMONG STUDENTS
Authors: Beridze Rusudan , Beridze Ketevan , Varshanidze Eteri , Meskhidze Shorena , Chinba Sofiko 
Published: June 2023

Rusudan Beridze
Email:r.beridze@bsu.edu.ge
Batumi Shota Rustaveli State University Associate Professor
Georgia, Batumi
https://orcid.org/0000-0001-5374-2815

Ketevan Beridze
Email:k.beridze@bsu.edu.ge
Batumi Shota Rustaveli State University Associate Professor
Georgia, Batumi
https://orcid.org/0000-0001-6268-7037

Eteri Varshanidze
Email:eteri.varshanize@bsu.edu.ge
Batumi Shota Rustaveli State University, Assistant
Georgia, Batumi
https://orcid.org/0000-0002-4779-2733

Shorena Meskhidze
Email:shorena.meskhidze@bsu.edu.ge
Batumi Shota Rustaveli State University, Assistant
Georgia, Batumi
https://orcid.org/0000-0001-9801-5347

Sofiko Chinba
Email:sofia.chinba@gmail.com
Master's student of clinical psychology
Georgia, Batumi
https://orcid.org/0000-0002-0329-3908
Modern life is full of stressful situations, so the study of the level of stress in various social groups has become especially relevant in recent years.
The main purpose of our study was to study the level of stress in today's youth. We also found it interesting to compare and determine whether there would be a difference in the level of stress among working and non-working young people who are only engaged in studies. In addition, we wanted to study the situation of young people living in urban and mountainous areas. According to the existing hypothesis, the level of stress among the inhabitants of the highlands should be significantly lower than that of the inhabitants of the city. We also found it interesting to study depression rates, here again on the assumption that depression rates would be significantly higher among urban youth than those living in the regions.
The results obtained allow us to conclude that students who are employed during their studies have an overall stress score almost twice as high as students who are not employed.
As the second stage of the study showed, our assumption that city dwellers would have a significantly higher level of stress was not confirmed. There is a difference, but a minor one.
As for the study of the level of depression, the results showed that the percentage of depressive states among students living in the city and region is very small. However, this study once again confirmed the link between stress levels and depression.
STRATEGIC APPROACHES OF COMPANY’S IMAGE MANAGEMENT IN MODER CONDITIONS
Authors: Mamuladze Gela , Mamuladze Nino 
Published: June 2023

Gela Mamuladze
E-mail: mamuladze.gela@bsu.edu.ge
Doctor of economics, Professor Batumi Shota Rustaveli State University
Georgia, Batumi
https://orcid.org/0000-0003-4194-7025

Nino Mamuladze
E-mail: nino.mamuladze@bsu.edu.ge
Doctor of Business Administration, assistant professor Batumi Shota Rustaveli State University
Georgia, Batumi
https://orcid.org/0000-0003-4159-5381

Abstract. In the modern global world, company’s image and the issues related to the image formation are among the most important task in business. This circumstance is especially relevant in the current period because the consumer has the opportunity to find out complete information about the brand in the shortest time, compare it with comparable products, and make a rational decision during the purchasing process. Image formation is not such an easy process therefore, giving appropriate attention from the company’s management is essential in order to establish a place in the market and gain a competitive advantage.
The image determines the company’s position in the market, outlines from concurrent, attracts the attention of potential customers, and maintains loyal customers. The image of the company significantly impacts its sales.
Based on the relevance of the presented issue, the purpose of our research was to study and investigate the necessary, facilitating, and hindering circumstances for the formation of the company’s image and to formulate relevant proposals.
Methodology/approach. The research methodology is based on the specificity of the research object, subject, goals and objectives. The method of bibliographic research, the logical analysis of relevant materials and data collection, is studying and researching the issues. Also, its presented practical materials, which were obtained based on the interview method used in the research process.
Research tasks. The main tasks and hypotheses of the research can be formulated as follows: identifying the public’s attitude towards the company’s image; identifying factors influencing the formation of a company’s image; and forming concrete issues about the research topic.
Practical value / results. the presented findings can be used by different companies in the process of forming an effective, distinctive and competitive image.
Originality and scientific novelty: the theoretical-practical aspects of the image are studied and ways to identify and eliminate problems related to its formation are proposed.
THE FOURTH INDUSTRIAL REVOLUTION AND STRATEGIC REGULARITIES OF MANAGEMENT AND COMPETITIVENESS IMPROVEMENT OF ECONOMIC ENTITIES
Authors: Halytsia Ihor , Oleksiuk Oleksii , Prokopenko Olha , Abashidze Giorgi , Berezianko Tamara 
Published: June 2023

Ihor Halytsia
E-mail: igalica@ukr.net
Doctor of Economics , Full Professor of National University of Food Technologies
Kyiv, Ukraine
https://orcid.org/0000-0002-1276-5743

Oleksii Oleksiuk
E-mail:oleksiuk@kneu.edu.ua
Doctor of Economics, Full Professor of Kyiv National Economic University named after Vadym Hetman
Kyiv, Ukraine
https://orcid.org/0000-0002-3407-6201

Olha Prokopenko
E-mail: prokopenko.olha.w@gmail.com
Doctor of Economics, Full Professor Sumy State Makarenko Pedagogical University
Sumy, Ukraine
https://orcid.org/0000-0003-1362-478X

Giorgi Abashidze
E-mail: g.abashidze@bntu.edu.ge
Assistant of Batumi Navigation Teaching University
Batumi, Georgia
https://orcid.org/0000-0002-3233-6890

Tamara Berezianko
E-mail: E-mail: tvb-nuft@i.ua
Doctor of Economics, Full Professor National University of Food Technologies
Kyiv, Ukraine
https://orcid.org/0000-0001-9228-4239

Abstract: A virtual intellectual economy is being formed due to the Fourth Industrial Revolution. The main characteristics of this economy are the virtualization of the whole social and economic life, an increase in the share of intellectual spheres of economic management in the real economy, intellectualization of mainly non-intellectual spheres of economic management. The development of the virtual-intellectual economy transforms the management of socio-economic systems and, first of all, of economic entities. New regularities of enterprise management emerge acceleration of the impact of the subject of activity on the object of activity, the impact of the subject of management activity on the object of management activity and event-driven management densification.
CHALLENGES OF HUMAN RESOURCE SELECTION IN GEORGIAN COMPANIES
Authors: Katamadze David , Davitadze Indira 
Published: June 2023

David Katamadze E-mail: qatamadze.davit@bsu.edu.ge Doctor of Economics, Associate Professor of Batumi Shota Rustaveli State University Batumi, Georgia https://orcid.org/0000-0003-2992-9326 Indira Davitadze E-mail: idavitadze91@gmail.com Batumi Shota Rustaveli State University, Phd student Batumi, Georgia https://orcid.org/0000-0002-6506-5273 Abstract: In the modern era, human resource management plays an increasingly important role in the success of a company. It is for this reason that the current nature of the mentioned topic is caused, since the main and driving goal of any organization is to achieve success. "In all types of organizations, whether large or small, manufacturing or service, people management is of prime importance. Without properly selected, positioned and professionally trained human resources, no organization can achieve its goals and survive." Within the competitive environment of the XXI century, where the business has become a rapidly developing field, new organizations are being created every day, the public mission of which is to provide the population with the goods and services it produces, while the goal is to achieve a high level of productivity, however, the success cannot be achieved if the process of selection and recruitment of existing human resources is carried out in the wrong way. The very workforce is the one that gives a company a distinct niche and edge over others. The human resource is the most critical resource that significantly determines the effectiveness of any organization. It is not easy to coordinate and direct the efforts of many people to achieve a common goal. [2] The human resources do not only imply the number of individuals, but also their knowledge, skills, qualifications, intelligence, experience and capabilities. In order the company to reach the international standards in the field of production of goods or sale of services, it is necessary to ensure staffing of personnel department with experienced managers who are responsible for the selection of appropriate and professional staff for the company. [6] Proper selection of human resources, management, and concern of the development is the key to the success of companies involved in business. The purpose of the present study is to develop correct and accurate recommendations for Georgian companies, taking into account the practical examples of international companies, which will allow them to improve the level of human resources management and help raise the level of productivity of employees.
STATE DEBT PORTFOLIO AND ITS MANAGEMENT TRENDS
Authors: Beridze Sophio , Tsintsadze Asie , Oniani Lela 
Published: June 2023

Sophio Beridze
Email:sopho1982@hotmail.com
PhD Students, Batumi Shota Rustaveli State University
Batumi, Georgia
https://orcid.org/0009-0002-7264-2873

Asie Tsintsadze
Email:asie.tsintsadze@bsu.edu.ge
Doctor of Economics, Professor, Batumi Shota Rustaveli State University
Batumi, Georgia
https://orcid.org/0000-0002-4493-8872

Lela Oniani
Email:lela.oniani@bsu.edu.ge
Associate Professor Batumi Shota Rustaveli State University
Batumi, Georgia
https://orcid.org/0000-0002-5960-4015

Coming out from tendency of increasing state debt annually, debt management issues is highly important for many countries of the world. In recent years state debt of Georgia and including foreign debt is at critical limit which makes negative impact on country’s debt rating. The questions arise in society: why does the state take debt? With what conditions? What is the benefits of society from debt? What are the consequences which state takes? Etc.
The goal of this Article is to demonstrate tendency for management issues of debt service indicators and accompanying risks of state debt of Georgia and state foreign debt. The article shows the role of state debt as debt asset and importance in economic development of country as well as historical aspects of state debt policy.
Methodology/Approach The structure and tendency are studied according to the last 20 years statistic data, inter –dependence quality of selected factors is evaluated.
Practical value/Implications - Though necessity for increasing domestic and foreign debt is explained by the necessity of more investment for achieving country development and economic goals, we consider that correct policy of state foreign debt management and high reliability of society it is necessary to elaborate debt necessity research in the form of file, also it should be clear what are the criterion for conferring privilege to existing debtor among alternate debtors. The measures which will promote the process of transforming foreign state debt to GDP to minimal limit, should be planned and elaborated.
AYAZ İSHAKÎ’NİN “SÜNNETÇİ DEDE” ADLI ÖYKÜSÜNDE MEKÂNIN POETİĞİ
Authors: ÇOPUR Gürhan 
Published: June 2023

Tatar aydınlanmasının öncü isimlerinden Ayaz İshakî (1878-1954) eserlerinde millî konuları ve toplumsal meseleleri ele alır. İdil-Ural havzası Türk topluluklarının hakları ve millî bilinci idrak etmesine yönelik politik çalışmaları edebi eserlerine de yansır. Roman, Öykü, Piyes gibi birçok türde eser vermiş olan İshakî, sürgünler ve kovuşturmalarla geçen yaşamını geniş bir külliyatla zenginleştirerek Tatar edebiyatının yönünü belirleyen isimler arasındaki yerini alır. Anlatı türlerinde mekân, yalnızca fizikî özellikler içeren; üzerinde/içerisinde yaşanan bir uzam olarak yer almaz. Anlatı türlerindeki mekân, üzerinde yaşanan, içerisinde barınılan yapısal ve çevresel özellikler içeren nesnel yönünün yanısıra fenomenolojik boyuttaki dikey boyutlu okumalara açık bir unsur olarak anlatı içerisinde etkin bir hale bürünür. Ayaz İshakî öykülerinde toplumsal ve millî konulara değinirken canlı betimlemeler ile mekânı kahramanın serüveninde güçlü bir unsur haline getirir. Toplumsal meseleler etrafında şekillenen öykücülüğü, realist gözlemlerin yardımıyla canlı ve gerçekçi tasvirler oluşturmasına olanak tanır. Bu yönüyle öykülerindeki mekânlar kahramanların karakter özelliklerini içerme/yansılama haricinde psikolojik değişim ve dönüşümlerini de takip eden bir dönüşüm sergilerler.
Bu çalışmada öyküleri, tiyatroları vd. gibi birçok türde verdiği eserler aracılığıyla İdil-Ural sahası Türk edebiyatının öncü kalemlerinden birisi olan Ayaz İshakî’nin Türkiye Türkçe’sine aktarılmış olan “Sünnetçi Dede” başlıklı uzun öyküsü mekânın poetiği bağlamında incelenecektir. Öyküde geçen mekân unsuru, metin içerisinde kazandığı dikey boyut aracılığıyla oluşturduğu sembolik bütünlük incelenirken Başkişi odağındaki kahraman-mekân ilişkisi çözümlenmeye çalışılacaktır.
Factors That Influence Good Governance in The Tanzania Football Federation
Authors: Mrindoko Allen , Issa Faisal H 
Published: June 2023

Effective management of sports activities entail adherence to some key governance tenets by bodies that oversee sports activities at territorial level. Factors for good governance were investigated in this paper to determine their influence on governance practices in Tanzania Football Federation. A cross-sectional descriptive design was adopted to collect quantitative data from 35 TFF staffs at national office, two region offices (Dar es Salaam and Morogoro) and 4 district offices using a structured questionnaire. The findings show that there is high level of transparency and accountability, financial transparency and control, human resources competence, and policy implementation in daily activities of Tanzania Football Federation. The empirical findings and theoretical thinking of this study contribute to a better understanding of the good governance and its significance on administration and development of sports. the results will also help sports federations or associations, clubs, and other stakeholders in their attempt to develop sports industry.
The Implication of the Development of Technology on Land Transportation Law in Indonesia
Authors: Sidiqah Meliyani 
Published: June 2023

Introduction: The emergence of online transportation provides significant changes in various aspects of people's lives. But its success raises protests from several groups for the abolition of online transportation. The rapid technological development of land transportation that cannot be accommodated by Indonesian law can affect the certainty of law. Further, it can provide legal protection to related parties.Purposes of the Research: This research aims to analyse the implication of online transportation as land transportation in Indonesia, and to recommend the accommodation of online transportation in Law Number 22 of 2009 on Road Traffic and Transportation to the Government of Indonesia.Methods of the Research: This research employed the normative juridical method by examining secondary data collected from library research using the statutory approach method analysed by qualitative technique.Results of the Research: The results show that the existence of online transportation as land transportation has positive implications for society such as the easier process, saving time, saves energy, can identify drivers, can track routes and vehicle locations, traffic monitoring, safety standards, lower costs, promos and discounts, efficient payment methods, and driver services. The other benefits are reducing the unemployment rate, increasing people's income, reducing the number of poverties, improving the people's welfare, and increasing the productivity of every institution and company. So, the government of Indonesia must accommodate online transportation in Law Number 22 of 2009 on Road Traffic and Transportation.