bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluasi Kesuksesan dan Penerimaan Microsoft Teams Pendekatan Model UTAUT, Delone & Mclean, Hot Fit
Authors: Zulpa Zulpa , Panjaitan Erwin Setiawan 
Published: February 2023

Microsoft TEAMS menjadi salah satu aplikasi yang digunakan oleh para dosen di Universitas Mikroskil sebagai media pembelajaran secara virtual. Dengan diimplementasikanya pembelajaran secara elektronik menggunakan Microsoft TEAMS tersebut, tentunya perlu dilakukan evaluasi untuk mengetahui faktor-faktor apa saja yang mempengaruhi kesuksesan dan penerimaan pengguna terhadap penggunaan Microsoft TEAMS di kalangan dosen Universitas Mikroskil. Oleh karena itu dibutuhkan model evaluasi yang sesuai untuk menilai kesuksesan dan penerimaan terhadap Microsoft TEAMS. Model yang digunakan untuk mengevaluasi kesuksesan dan penerimaan pengguna terhadap Microsoft TEAMS di kalangan dosen Universitas Mikroskil adalah model gabungan yang terdiri dari model UTAUT, model kesuksesan SI DeLone dan McLean, dan model kesesuaian Human-Organization-Technology Fit (HOT Fit). Populasi dalam penelitian ini adalah dosen Universitas Mikroskil yang masih aktif mengajar dan menggunakan Ms. Teams. Besarnya jumlah dosen yang mengisi koesioner dalam penelitian ini yaitu 95 orang. Hasil penelitian menggunakan gabungan ketiga model ini ialah faktor manusia, faktor teknologi mempengaruhi minat, minat menggunakan Microsoft TEAMS berpengaruh terhadap manfaat yang didapatkan dosen, faktor teknologi mempengaruhi kepuasan dosen dalam menggunakan Microsoft TEAMS serta ada hubungan kesesuaian faktor manuasia, teknologi dan organisasi.
Evaluation of Planting Methods for Rice in Rice-Wheat Zone of Sheikhupura, Pakistan
Authors: Hassan Usman , Ali Liaqat , Yonus Muhammad , Qamar Wardah , Chauhdhary Tariq , Hassan Ishtiaq , Hassan Ishtiaq , Hussain Shabir 
Published: February 2023

This study was conducted to evaluate different planting methods for rice crops in the rice wheat zone of Sheikhupura Pakistan for the year 2019-2020. Four planting methods were tested in this study conventional transplanting of rice, 2- Manual transplanting of rice by rope, 3-Mechanical transplanting of rice and 4-Direct seeding of rice. Among all these methods, the mechanical transplanting of rice method proved to perform best in terms of meeting recommended plant population of rice crop, rice crop yield and yield parameters followed by manual transplanting of rice by rope method and direct seeding of rice method. Mechanical transplanting of rice is a mechanized technology for sowing rice crops; solving labor problems and time management. Transplanting of rice by rope method is a laborious method. Direct seeding of rice method also fulfil labour, and plant population issues with proper weeds management, Conventional transplanting of rice method performed poorly in terms of plant population, yield and yield parameters.
DNA methylation differences in monozygotic twins with Van der Woude syndrome
Authors: Petrin A. L. , Zeng E. , Thomas M. A. , Moretti-Ferreira D. , Marazita M. L. , Xie X. J. , Murray J. C. , Moreno-Uribe L. M. 
Published: February 2023

IntroductionVan der Woude syndrome (VWS) is an autosomal dominant disorder responsible for 2% of all syndromic orofacial clefts (OFCs), with IRF6 being the primary causal gene (70%). Cases may present with lip pits and either cleft lip, cleft lip with cleft palate, or cleft palate, with marked phenotypic discordance even among individuals carrying the same mutation. This suggests that genetic or epigenetic modifiers may play additional roles in the syndrome's etiology and variability in expression. We report the first DNA methylation profiling of two pairs of monozygotic twins with VWS. Our goal is to explore epigenetic contributions to VWS etiology and variable phenotypic expressivity by comparing DNAm profiles in both twin pairs. While the mutations that cause VWS in these twins are known, the additional mechanism behind their phenotypic risk and variability in expression remains unclear.MethodsWe generated whole genome DNAm data for both twin pairs. Differentially methylated positions (DMPs) were selected based on: (1) a coefficient of variation in DNAm levels in unaffected individuals &lt;20%, and (2) intra-twin pair absolute difference in DNAm levels &gt;5% (Δβ &gt; |0.05|). We then divided the DMPs into two subgroups for each twin pair for further analysis: (1) higher methylation levels in twin A (Twin A &gt; Twin B); and (2) higher methylation levels in twin B (Twin B &gt;Twin A).Results and DiscussionGene ontology analysis revealed a list of enriched genes that showed significant differential DNAm, including clef-associated genes. Among the cleft-associated genes, TP63 was the most significant hit (p = 7.82E-12). Both twin pairs presented differential DNAm levels in CpG sites in/near TP63 (Twin 1A &gt; Twin 1B and Twin 2A &lt; Twin 2B). The genes TP63 and IRF6 function in a biological regulatory loop to coordinate epithelial proliferation and differentiation in a process that is critical for palatal fusion. The effects of the causal mutations in IRF6 can be further impacted by epigenetic dysregulation of IRF6 itself or genes in its pathway. Our data show evidence that changes in DNAm are a plausible mechanism that can lead to markedly distinct phenotypes, even among individuals carrying the same mutation.
Geochemistry and geochronology of basic igneous rocks in Bairin Right banner, southeastern inner Mongolia, China: Implications for the final closure of the Paleo—Asian Ocean along the Xar Moron suture zone
Authors: Yang Wenpeng , Li Chenglu , Alam Masroor , Fu Anzong , Zheng Bo , Yang Yuanjiang , Hu Xiaofang 
Published: February 2023

This paper reports the first discovery of basic igneous rocks in Bairin Right Banner in southeastern Inner Mongolia, China. To understand the genesis and tectonic evolution of these rocks, we have carried out geochronology and geochemistry research on them. The results show that LA-ICP-MS zircon U-Pb concordant mean ages of massive basalt, diabase, and pillow basalt are 272.0 ± 2.8 Ma, 261.5 ± 3.2 Ma, and 256.5 ± 2.5 Ma, respectively, suggesting their formation during the Late Permian. The massive basalt, diabase, and pillow basalt are tholeiitic with low Mg# values in the ranges of 46.2–66.8, 54.4–71.0, and 53.5–58.2, respectively. They have similar chondrite-normalized rare earth element (REE) patterns. The intensity of REE differentiation is similar to that of typical enriched mid-ocean ridge basalts (E-MORB). The pillow basalts are relatively enriched in Ba and U, while slightly depleted in Rb and Th, and show geochemical affinity to E-MORB. The massive basalts and diabases have the same primitive mantle-normalized patterns and are relatively enriched in Rb, Ba, and U, while depleted in Nb and Ta, similar to the typical island arc magmas. Our new findings indicate that the intra-oceanic subduction of the Paleo-Asian Oceanic slab was still ongoing during the late Permian in the Bairin Right Banner area and, combined with previous studies, it might have been closed during the Late Permian to Early Triassic along the Xar Moron suture zone.
Sequencing technology as a major impetus in the advancement of studies into rheumatism: A bibliometric study
Authors: Huang Runzhi , Tang Jieling , Wang Siqiao , Liu Yifan , Zhang Mengyi , Jin Minghao , Qin Hengwei , Qian Weijin , Lu Yuwei , Yang Yiting , Lu Bingnan , Yao Yuntao , Yan Penghui , Huang Jie , Zhang Wei , Lu Jianyu , Gu Minyi , Zhu Yushu , Guo Xinya , Xian Shuyuan , Liu Xin , Huang Zongqiang 
Published: February 2023

BackgroundRheumatism covers a wide range of diseases with complex clinical manifestations and places a tremendous burden on humans. For many years, our understanding of rheumatism was seriously hindered by technology constraints. However, the increasing application and rapid advancement of sequencing technology in the past decades have enabled us to study rheumatism with greater accuracy and in more depth. Sequencing technology has made huge contributions to the field and is now an indispensable component and powerful tool in the study of rheumatism.MethodsArticles on sequencing and rheumatism, published from 1 January 2000 to 25 April 2022, were retrieved from the Web of Science™ (Clarivate™, Philadelphia, PA, USA) database. Bibliometrix, the open-source tool, was used for the analysis of publication years, countries, authors, sources, citations, keywords, and co-words.ResultsThe 1,374 articles retrieved came from 62 countries and 350 institutions, with a general increase in article numbers during the last 22 years. The leading countries in terms of publication numbers and active cooperation with other countries were the USA and China. The most prolific authors and most popular documents were identified to establish the historiography of the field. Popular and emerging research topics were assessed by keywords and co-occurrence analysis. Immunological and pathological process in rheumatism, classification, risks and susceptibility, and biomarkers for diagnosis were among the hottest themes for research.ConclusionsSequencing technology has been widely applied in the study of rheumatism and propells research in the area of discovering novel biomarkers, related gene patterns and physiopathology. We suggest that further efforts be made to advance the study of genetic patterns related to rheumatic susceptibility, pathogenesis, classification and disease activity, and novel biomarkers.
Adiponectin/leptin ratio as a predictor of acute rejection in early post-transplant period in patients after kidney transplantation
Authors: Graňák Karol , Vnučák Matej , Beliančinová Monika , Kleinová Patrícia , Pytliaková Margaréta , Mokáň Marián , Dedinská Ivana 
Published: February 2023

IntroductionAdipokines are largely involved in the regulation of immune system activity. While leptin is the main pro-inflammatory marker of adipose tissue, adiponectin is characterized by anti-inflammatory effects. The aim of our study was to determine the risk of acute graft rejection in protocol biopsy depending on the adiponectin/leptin (A/L) ratio in patients after kidney transplantation (KT).Materials and methodsA total of 104 patients were included in the prospective analysis, in whom the levels of adipokines were examined pre-transplant, in the 3rd month after KT and the A/L ratio was calculated. In the 3rd month after KT, all patients underwent protocol biopsy of the graft and examination of donor-specific antibodies (DSA) using the Luminex method.ResultsAfter adjusting for differences in the basic characteristics of the donor and recipient, we identified a subgroup with A/L ratio &lt; 0.5 pre-transplant [HR 1.6126, (P = 0.0133)] and 3 months after KT [HR 1.3150, (P = 0.0172)] as independent risk factor for acute graft rejection. In the subsequent specification of the rejection episode, we identified the risk ratio A/L &lt; 0.5 before KT [HR 2.2353, (P = 0.0357)] and 3 months after KT [HR 3.0954, (P = 0.0237)] as independent risk factor for the development of acute humoral rejection with DSA positivity.ConclusionThis is the first study to investigate the relationship between A/L ratio and immunological risk in terms of the development of rejection changes in patients after KT. In our study, we found that A/L ratio &lt; 0.5 is an independent risk factor for the development of acute humoral rejection and de novo DSA production in the third month after KT.
First characterization of cultivable extremophile Chroococcidiopsis isolates from a solar panel
Authors: Baldanta Sara , Arnal Raquel , Blanco-Rivero Amaya , Guevara Govinda , Navarro Llorens Juana María 
Published: February 2023

IntroductionMicroorganisms colonize a wide range of natural and artificial environments. Even though most of them are unculturable in laboratory conditions, some ecosystems are ideal niches for bioprospecting extremophiles with unique properties. Up today, there are few reports concerning microbial communities found on solar panels, a widespread, artificial, extreme habitat. Microorganisms found in this habitat belong to drought-, heat- and radiation-adapted genera, including fungi, bacteria, and cyanobacteria.MethodsHere we isolated and identified several cyanobacteria from a solar panel. Then, some strains isolated were characterizated for their resistance to desiccation, UV-C exposition, and their growth on a range of temperature, pH, NaCl concentration or diverse carbon and nitrogen sources. Finally, gene transfer to these isolates was evaluated using several SEVA plasmids with different replicons to assess their potential in biotechnological applications.Results and discussionThis study presents the first identification and characterization of cultivable extremophile cyanobacteria from a solar panel in Valencia, Spain. The isolates are members of the genera Chroococcidiopsis, Leptolyngbya, Myxacorys, and Oculatella all genera with species commonly isolated from deserts and arid regions. Four of the isolates were selected, all of them Chroococcidiopsis, and characterized. Our results showed that all Chroococcidiopsis isolates chosen were resistant up to a year of desiccation, viable after exposition to high doses of UV-C, and capable of being transformed. Our findings revealed that a solar panel is a useful ecological niche in searching for extremophilic cyanobacteria to further study the desiccation and UV-tolerance mechanisms. We conclude that these cyanobacteria can be modified and exploited as candidates for biotechnological purposes, including astrobiology applications.
Remote scoring models of rigidity and postural stability of Parkinson’s disease based on indirect motions and a low-cost RGB algorithm
Authors: Ma Ling-Yan , Shi Wei-Kun , Chen Cheng , Wang Zhan , Wang Xue-Mei , Jin Jia-Ning , Chen Lu , Ren Kang , Chen Zhong-Lue , Ling Yun , Feng Tao 
Published: February 2023

Background and objectivesThe Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale Part III (MDS-UPDRS III) is mostly common used for assessing the motor symptoms of Parkinson’s disease (PD). In remote circumstances, vision-based techniques have many strengths over wearable sensors. However, rigidity (item 3.3) and postural stability (item 3.12) in the MDS-UPDRS III cannot be assessed remotely since participants need to be touched by a trained examiner during testing. We developed the four scoring models of rigidity of the neck, rigidity of the lower extremities, rigidity of the upper extremities, and postural stability based on features extracted from other available and touchless motions.MethodsThe red, green, and blue (RGB) computer vision algorithm and machine learning were combined with other available motions from the MDS-UPDRS III evaluation. A total of 104 patients with PD were split into a train set (89 individuals) and a test set (15 individuals). The light gradient boosting machine (LightGBM) multiclassification model was trained. Weighted kappa (k), absolute accuracy (ACC ± 0), and Spearman’s correlation coefficient (rho) were used to evaluate the performance of model.ResultsFor model of rigidity of the upper extremities, k = 0.58 (moderate), ACC ± 0 = 0.73, and rho = 0.64 (moderate). For model of rigidity of the lower extremities, k = 0.66 (substantial), ACC ± 0 = 0.70, and rho = 0.76 (strong). For model of rigidity of the neck, k = 0.60 (moderate), ACC ± 0 = 0.73, and rho = 0.60 (moderate). For model of postural stability, k = 0.66 (substantial), ACC ± 0 = 0.73, and rho = 0.68 (moderate).ConclusionOur study can be meaningful for remote assessments, especially when people have to maintain social distance, e.g., in situations such as the coronavirus disease-2019 (COVID-19) pandemic.
Surgical resection of intracranial cavernous hemangioma located at uncommon location: Clinical presentation and management
Authors: Li Jiuhong , Zhang Guisheng , Ma Qiang , Li Xiang , He Jiaojiang 
Published: February 2023

BackgroundIntracranial cavernous hemangiomas (CHs) usually originate from the cerebral and cerebellar hemispheres, while the clinical features and optimum treatment of CHs that originate from atypical locations remain unclear.MethodsWe conducted a retrospective analysis of CHs that originated from the sellar, suprasellar, or parasellar region, the ventricular system, the cerebral falx, or the meninges in patients who underwent surgery from 2009 to 2019 in our department.ResultsIn our study, fourteen patients with pathologically confirmed CHs in uncommon locations (UCHs) were enrolled; 5 were located at the sellar or parasellar region, 3 at the suprasellar region, 3 at the ventricular system, 2 at the cerebral falx, and 1 originated from parietal meninges. The most common symptoms were headache and dizziness (10/14); however, none presented with seizures. All UCHs located in the ventricular systems and 2 of the 3 UCHs located in the suprasellar region manifested as hemorrhagic lesions and shared similar radiological features compared with axial CHs; other locations of UCHs did not have a “popcorn” appearance on T2-weighted image. Nine patients achieved GTR, 2 achieved STR, and 3 achieved PR. Four out of five patients who received incomplete resection underwent adjuvant gamma-knife radiosurgery. During the average follow-up of 71.1 ± 43.3 months, no patient died and one patient encountered recurrence and de novo formation of midbrain CH. Most patients had an excellent KPS score of 90–100 (9 of 14) or a good KPS score of 80 (1 of 14).ConclusionWe suggest that surgery is the optimum therapeutic method for UCHs located at the ventricular system, dura mater, and cerebral falx. Stereotactic radiosurgery plays an important role in the treatment of UCHs located at the sellar or parasellar region and remnant UCHs. Favorable outcomes and lesion control could be achieved by surgery.
Glycemic index and insulin index after a standard carbohydrate meal consumed with live kombucha: A randomised, placebo-controlled, crossover trial
Authors: Atkinson Fiona S. , Cohen Marc , Lau Karen , Brand-Miller Jennie C. 
Published: February 2023

IntroductionKombucha is a complex probiotic beverage made from fermented tea, yet despite extensive historical, anecdotal, and in-vivo evidence for its health benefits, no controlled trials have been published on its effect on humans.MethodsWe conducted a randomised placebo-controlled, cross-over study that examined the Glycemic Index (GI) and Insulin Index (II) responses after a standardised high-GI meal consumed with three different test beverages (soda water, diet lemonade soft drink and an unpasteurised kombucha) in 11 healthy adults. The study was prospectively registered with the Australian New Zealand Clinical Trials Registry (anzctr.org.au: 12620000460909). Soda water was used as the control beverage. GI or II values were calculated by expressing the 2-h blood glucose or insulin response as a percentage of the response produced by 50 g of glucose dissolved in water.ResultsThere was no statistically significant difference in GI or II between the standard meal consumed with soda water (GI: 86 and II: 85) or diet soft drink (GI: 84 and II: 81, (p = 0.929 for GI and p = 0.374 for II). In contrast, when kombucha was consumed there was a clinically significant reduction in GI and II (GI: 68, p = 0.041 and II: 70, p = 0.041) compared to the meal consumed with soda water.DiscussionThese results suggest live kombucha can produce reductions in acute postprandial hyperglycemia. Further studies examining the mechanisms and potential therapeutic benefits of kombucha are warranted.
Effects of high night temperature on soybean yield and compositions
Authors: Yang Lin , Song Wenwen , Xu Cailong , Sapey Enoch , Jiang Dong , Wu Cunxiang 
Published: February 2023

IntroductionSoybean is sensitive to light and temperature. Under the background of global asymmetric climate warming.MethodsThe increase of night temperature may have an important impact on soybean yield. In this study, three varieties with different level of protein were planted under 18°C and 28°C night temperatures for investigating the effects of high night temperatures on soybean yield formation and the dynamic changes of non-structural carbohydrates (NSC) during the seed filling period (R5-R7).Results and discussionThe results indicated that high night temperatures resulted in smaller seed size, lower seed weight, and a reduced number of effective pods and seeds per plant, and thus, a significant reduction in yield per plant. Analysis of the seed composition variations showed carbohydrates were more substantially affected by high night temperature than protein and oil. We observed “carbon hunger” caused by high night temperature increased photosynthesis and sucrose accumulation in the leaves during the early stage of high night temperature treatment. With elongated treated time, the excessive carbon consumption led to the decrease of sucrose accumulation in soybean seeds. Transcriptome analysis of leaves after 7 days of treatment showed that the expression of most sucrose synthase and sucrose phosphatase genes decreased significantly under the high night temperature. Which could be another important reason for the decrease of sucrose. These findings provided a theoretical basis for enhancing the tolerance of soybean to high night temperature.
Is the SES and academic achievement relationship mediated by cognitive ability? Evidence from PISA 2018 using data from 77 countries
Authors: Boman Björn 
Published: February 2023

IntroductionEarlier research has suggested that that the international large-scale assessment, PISA (Programme for International Student Assessment), may be looked upon as a form of school test that is mostly explained by participating students’ socioeconomic status, non-cognitive factors, and various school factors, whereas another strand of research focuses on the similarities between PISA and cognitive ability assessments such as IQ tests. The latter position does also highlight the strong relationships between PISA scores and IQ test scores, typically aggregated to the country level. The current article adds to this scholarly debate by examining the latest PISA survey from 2018.MethodsCorrelation, regression, moderator, and mediation analyses were run for aggregated country-level data (N = 77) from PISA 2018.ResultsThe results indicate that PISA scores indeed are strongly associated with both cognitive ability test scores and socioeconomic status indicators such as average annual national income.DiscussionA more nuanced position suggests that PISA should be labelled a test that measures cognitive school skills rather than a proxy of national IQ, as the link between country-level abilities and school age abilities is neither causal, nor theoretically and empirically palpable, yet partly robust.