bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using sediment geochemical records to infer past lake-water total phosphorus concentrations at a site with high internal P loading, Lake Søbygaard, Denmark
Authors: Boyle John , Moyle Madeleine , Søndergaard Martin , Jeppesen Erik 
Published: January 2023

AbstractIn lakes where phosphorus (P) supply is dominated by external loads, long-term mean lake-water total phosphorus (TP) concentrations can be successfully reconstructed from sediment P profiles and dating using the Sediment-Inferred lake-water Total Phosphorous (SI-TP) mass balance model. However, it has not yet been shown that the model is applicable at lakes with high internal P loading, where sediment diagenesis releases P to the water column and degrades the sediment P record. Here we apply the SI-TP model to Lake Søbygaard in Denmark, a shallow lake with exceptionally high internal P loading for several decades since the external loading was reduced by 80–90% in 1982. Our aim was to test the impact of this sediment degradation on P record integrity. Using six published sediment P records collected over the period 1985–2004, we applied the model without site-specific calibration. Degradation of the sediment P record by diagenesis was observed, and occurred at a rate consistent with theoretical models, offering a potential approach to correct for degradation. Even neglecting degradation, the resulting SI-TP record was found to be similar in magnitude and temporal trend to the corresponding monitored TP values. From this test of SI-TP model performance at Lake Søbygaard we conclude that the model has the potential to be more widely applied at lakes with high internal P loading.
Comprehensive INGO Accountability to Strengthen Perceived Program Effectiveness: A Logical Thing?
Authors: Hengevoss Alice 
Published: January 2023

AbstractThe accountability of international nongovernmental organizations (INGOs) has come under closer public and academic scrutiny. Critics call for a more comprehensive approach to accountability—one that addresses a wider set of stakeholders, and beneficiaries in particular. There is an increase in empirical evidence suggesting that comprehensive accountability has positive implications for the organizational performance. This article develops a framework for comprehensive INGO accountability and tests its implications on program effectiveness. The framework describes three accountability meta-logics: the resource logic, outcome assessment logic, and discursive logic. Applying partial least squares structural equation modeling, the impact of these meta-logics on perceived program effectiveness as well as their drivers is tested. The analysis is based on a unique data set from an international survey among 201 INGO leaders from 21 countries. The findings suggest that comprehensive accountability indeed strengthens the perceived program effectiveness. The study emphasizes the managerial argument that implementing comprehensive accountability, not only is the “right thing” to do, but also has the strategic advantage of strengthening perceived mission achievement.
The osteoporosis treatment gap in Switzerland between 1998 and 2018
Authors: Lippuner Kurt , Moghadam Bita Yousefi , Schwab Patrick 
Published: January 2023

Abstract

Summary

The annual number of patients treated for osteoporosis between 1998 and 2018 in Switzerland increased until 2008 and steadily decreased thereafter. With a continuously growing population at fracture risk exceeding an intervention threshold, the treatment gap has increased and the incidence of hip fractures has stopped declining in the past decade.

Introduction

The existence of an osteoporosis treatment gap, defined as the percentage of patients at risk for osteoporotic fractures exceeding an intervention threshold but remaining untreated, is widely acknowledged. Between 1998 and 2018, new bone active substances (BAS) indicated for the treatment of osteoporosis became available. Whether and if so to what extent these new introductions have altered the treatment gap is unknown.

Methods

The annual number of patients treated with a BAS was calculated starting from single-drug unit sales. The number of patients theoretically eligible for treatment with a BAS was estimated based on four scenarios corresponding to different intervention thresholds (one based solely on a bone mineral density T score threshold and three FRAX-based thresholds) and the resulting annual treatment gaps were calculated.

Results

In Switzerland, the estimated number of patients on treatment with a BAS increased from 35,901 in year 1998 to 233,381 in year 2018. However, this number grew regularly since 1998, peaked in 2008, and steadily decreased thereafter, in timely coincidence with the launch of intravenous bisphosphonates and the RANKL inhibitor denosumab. When expressed in numbers of untreated persons at risk for osteoporotic fractures exceeding a given intervention threshold, the treatment gaps were of similar magnitude in 1998 (when the first BSAs just had become available) and 2018. There was a strong association, which does not imply causation, between the proportion of patients treated and hip fracture incidence.

Conclusion

In Switzerland, the osteoporosis treatment gap has increased over the past decade. The availability of new BAS has not contributed to its decrease.
Pre-reduction of United Manganese of Kalahari Ore in CO/CO2, H2/H2O, and H2 Atmospheres
Authors: Davies J. , Tangstad M. , Schanche T. L. , du Preez S. P. 
Published: January 2023

Abstract
The incorporation of hydrogen, which is a relatively unexplored reductant used during ferromanganese (FeMn) production, is an attractive approach to lessen atmospheric gaseous carbon release. The influence of hydrogen on the pre-reduction of carbonate-rich United Manganese of Kalahari (UMK) ore from South Africa was investigated. Experiments were performed in 70 pct CO 30 pct CO2 (reference), 70 pct H2 30 pct H2O, and 100 pct H2 gas atmospheres at 700 °C, 800 °C, and 900 °C. Calculated phase stability diagrams and experimental results showed good correlation. The pre-reduction process involved two reactions proceeding in parallel, i.e., the pre-reduction of higher oxides and the decomposition of carbonates present in the ore. A thermogravimetric (TG) furnace was employed for the pre-reduction of the ore in various atmospheres. The calculated weight loss percentage was used to determine the degree and rate of pre-reduction. It was found that the oxidation state of higher Fe- and Mn-oxides was lowered when treated in 70 pct H2 30 pct H2O and 70 pct CO 30 pct CO2, whereas FeO was metalized when using 100 pct H2. As for the intrinsic carbonates, the majority thereof were decomposed in the CO/CO2 atmosphere at 900 °C, and ≥ 700 °C in the H2/H2O and H2 atmospheres. Additionally, the degree and rate of reduction were accelerated by increasing the pre-reduction temperature and by employing a hydrogen-containing gas atmosphere (70 pct H2 30 pct H2O, and 100 pct H2). Scanning electron microscopy and electron microprobe analysis revealed the presence of three phases in the pre-reduced ore: (i) Mn- and Fe-rich, (ii) Mg- and Ca-rich, and (iii) Mg-, Si-, K-, and Na-rich. It was also found that there were no appreciable differences in porosity and decrepitation of the ores treated in the CO/CO2 and hydrogen-containing atmospheres. The use of a hydrogen atmosphere showed potential for the pre-reduction of carbonate-containing manganese ores as it accelerated the decomposition of the carbonates as well as facilitated the metallization of Fe-oxides present in the ore.
Have Therapeutics Enhanced Our Knowledge of Axial Spondyloarthritis?
Authors: Harrison S. R. , Marzo-Ortega H. 
Published: January 2023

Abstract
Purpose of Review

An overview of how the treatment landscape of axial spondyloarthritis (axSpA) has shaped our understanding of the disease.

Recent Findings
Prior to the millennium, non-steroidal anti-inflammatory drugs (NSAIDs) were the only treatment for axSpA, yet only 30% of patients responded and many developed side effects. In 2003, the first biological disease-modifying drug (bDMARD) was licensed for axSpA which substantially improved outcomes in comparison to NSAIDs. In 2022, there are now several bDMARDs for axSpA; however, they too are not universally efficacious in treating axial inflammation and may have deleterious effects on extramusculoskeletal manifestations. Nevertheless, successful or not, each bDMARD gives invaluable insight into axSpA immunobiology.

Summary
This review discusses how much we have learned from the use of bDMARDs in axSpA, how this has redefined our understanding of the disease, and how we might use this knowledge to develop new and better treatments for axSpA in the future.
Valorization of faba bean (Vicia faba) by-products
Authors: Krenz Lina Maja Marie , Grebenteuch Sandra , Zocher Kathleen , Rohn Sascha , Pleissner Daniel 
Published: January 2023

AbstractFrom
harvesting to consumption of the faba bean (Vicia faba), different plant residues such as stems, leaves, pods, and seed husks remain as by-products. The harvest residues constitute about 50% (w/w) of the whole aboveground biomass, while the empty pods and the seed husks account for 11% and 6% (w/w) on average, respectively. Due to the environmental and dietary benefits, the global production of faba beans is most likely to increase in the future. Concomitantly, the amounts of by-products will rise as well. So far, mainly the harvest residues have been widely studied, whereas the pods and husks have received less consideration. Therefore, the aim of this review was to provide an overview of the composition of the faba bean plant residues and to illustrate their potential of being used as feedstock in food, feed, or even non-food applications. This literature survey clearly reveals that all the residual materials of faba beans contain valuable compounds and might be suitable for a multitude of different applications. The residual material should thus not be disposed of but further valorized in order to exploit the full potential of the biomass.
Emerging MoS2 Wafer-Scale Technique for Integrated Circuits
Authors: Ye Zimeng , Tan Chao , Huang Xiaolei , Ouyang Yi , Yang Lei , Wang Zegao , Dong Mingdong 
Published: January 2023

AbstractAs an outstanding representative of layered materials, molybdenum disulfide (MoS2) has excellent physical properties, such as high carrier mobility, stability, and abundance on earth. Moreover, its reasonable band gap and microelectronic compatible fabrication characteristics makes it the most promising candidate in future advanced integrated circuits such as logical electronics, flexible electronics, and focal-plane photodetector. However, to realize the all-aspects application of MoS2, the research on obtaining high-quality and large-area films need to be continuously explored to promote its industrialization. Although the MoS2 grain size has already improved from several micrometers to sub-millimeters, the high-quality growth of wafer-scale MoS2 is still of great challenge. Herein, this review mainly focuses on the evolution of MoS2 by including chemical vapor deposition, metal–organic chemical vapor deposition, physical vapor deposition, and thermal conversion technology methods. The state-of-the-art research on the growth and optimization mechanism, including nucleation, orientation, grain, and defect engineering, is systematically summarized. Then, this review summarizes the wafer-scale application of MoS2 in a transistor, inverter, electronics, and photodetectors. Finally, the current challenges and future perspectives are outlined for the wafer-scale growth and application of MoS2.
Synthesis, characterization, safety design, and application of NPs@BC for contaminated soil remediation and sustainable agriculture
Authors: Zheng Tong , Ouyang Shaohu , Zhou Qixing 
Published: January 2023

AbstractBiochar (BC) and nanoparticle-decorated biochar (NPs@BC) have emerged as potential high-performance function materials to facilitate simultaneous soil remediation and agricultural production. Therefore, there is an urgent need to incorporate environmental sustainability and human health targets into BC and NPs@BC selection and design processes. In contrast to extensive research on the preparation, modification, and environmental application of BC to soil ecosystems, reports about the adapted framework and material selection strategy of NPs@BC under environmental and human health considerations are still limited. Nevertheless, few studies systematically explored the impact of NPs@BC on soil ecosystems, including soil biota, geochemical properties, and nutrient cycles, which are critical for large-scale utilization as a multifunctional product. The main objective of this systematic literature review is to show the high degrees of contaminant removal for different heavy metals and organic pollutants, and to quantify the economic, environmental, and toxicological outcomes of NPs@BC in the context of sustainable agriculture. To address this need, in this review, we summarized synthesis techniques and characterization, and highlighted a linkage between the evolution of NPs@BC properties with the framework for sustainable NPs@BC selection and design based on environmental effects, hazards, and economic considerations. Then, research advances in contaminant remediation for heavy metals and organic pollutants of NPs@BC are minutely discussed. Eventually, NPs@BC positively acts on sustainable agriculture, which is declared. In the meantime, evaluating from the perspective of plant growth, soil characterizations as well as carbon and nitrogen cycle was conducted, which is critical for comprehending the NPs@BC environmental sustainability. Our work may develop a potential framework that can inform decision-making for the use of NPs@BC to facilitate promising environmental applications and prevent unintended consequences, and is expected to guide and boost the development of highly efficient NPs@BC for sustainable agriculture and environmental applications.
Graphical Abstract
On the role of inertia in channel flows of finite-size neutrally buoyant particles
Authors: Yousefi Ali , Costa Pedro , Picano Francesco , Brandt Luca 
Published: January 2023

We consider suspensions of finite-size neutrally buoyant rigid spherical particles in channel flow and investigate the relevance of different momentum transfer mechanisms and the relation between the local particle dynamics and the bulk flow properties in the highly inertial regime. Interface-resolved simulations are performed in the range of Reynolds numbers

$3000 \leq Re \leq 15\ 000$

and solid volume fractions

$0 \leq \phi \leq 0.3$

. The Lagrangian particle statistics show that pair interactions are highly inhomogeneous and dependent on the distance from the wall: in their vicinity, the underlying mean shear drives the pair interactions, while a high degree of isotropy, dictated by more frequent collisions, characterizes the core region. Analysis of the momentum balance reveals that while the particle-induced stresses govern the dynamics in dense conditions,

$\phi =0.3$

, and moderate Reynolds numbers,

$Re <10\ 000$

, the turbulent stresses take over at higher Reynolds numbers. This behaviour is associated with a reduced particle migration toward the channel core, which decreases the importance of the particle-induced stress and increases the turbulent activity. Our results indicate that Reynolds stresses and the associated velocity fluctuations, characteristics of near-wall turbulence, prevail at high inertia over the resistance to deformation presented by the particles for volume fractions lower than 30 %.
COVID-19, the Global Financial Crisis, and the Regulation of Labor Migration
Authors: Yaroshenko Oleg M. , Harashchuk Volodymyr М. , Moskalenko Olena V. , Melnychuk Nataliia O. , Burniagina Yuliia M. 
Published: January 2023

AbstractThe development of globalization processes in the world economy allows reconciling supply and demand for staff regardless of the employee's country of origin and leads to international labor migration. The experience of highly developed countries shows that a country's economy and its subsequent growth largely depend on the effective recruitment and use of skilled labor. The COVID-19 pandemic has led to a drastic restriction on population mobility and, consequently, worsened the economic and social situations in countries where labor migration was a widespread phenomenon. The ensuing economic crisis has not only altered trends in labor migration but has also brought new challenges to its legal regulation. The article aims to determine the features of migration trends and policy in the COVID-19 environment, examine them in the context of new regulations adopted to protect the labor rights of migrants under the current circumstances, suggest effective measures to regulate the situation in the labor market, and address the economic crises in the countries of destination and origin. The examination of this issue involved a complex methodological framework where the general scientific dialectical method was central to the research. The conducted research provides a foundation for overcoming the social and economic crises caused by COVID-19, which contributes to its practical significance.
Gothic visibilities and International Relations: Uncanny icons, critical comics, and the politics of abjection in Aleppo
Authors: Windfeld Frederik Carl , Hvithamar Marius Hauge , Hansen Lene 
Published: January 2023

AbstractThe war in Syria has been communicated to global audiences through images of dead and injured children, decapitated and tortured bodies, and ruined cities. The article shows how news media coverage of the war's impact on the city of Aleppo invoked a Gothic tradition. Drawing on Kristeva and Freud's concepts of the abject and the uncanny, the article argues that the Gothic tradition can further International Relations research on the constitution of Selves and Others. The Gothic Other is constituted through the (Gothic) Self's repulsion, fascination, and desire, and the Gothic tradition revolves around an understanding of the invisible as an in-between space of fear and anticipation. The ability to recognise Gothic themes in an image depends on one's familiarity with the Gothic tradition, hence images are theorised as having a Gothic potentiality. The article focuses on how the Anglo-Saxon Gothic tradition enabled Western readers to identify Gothic themes in news coverage of the war in Aleppo. The article adopts a multimethod strategy including a content analysis of 457 images published by Western news media; a discourse analysis of news stories; an analysis of three Gothic, uncanny iconic motifs; and an author-created comic drawing on Gothic elements from the published photographs.
Optimal robotic assembly sequence planning with tool integrated assembly interference matrix
Authors: Champatiray Chiranjibi , Raju Bahubalendruni M. V. A. , Mahapatra Rabindra Narayan , Mishra Debasisha 
Published: January 2023

Abstract
Manufacturing industries are looking for efficient assembly planners that can swiftly develop a practically feasible assembly sequence while keeping costs and time to a minimum. Most assembly sequence planners rely on part relations in the virtual environment. Nowadays, tools and robotic grippers perform most of the assembly tasks. Ignoring the critical aspect renders solutions practically infeasible. Additionally, it is vital to test the feasibility of positioning and assembling components while employing robotic grippers and tools prior to their implementation. This paper presents a novel concept named by considering both part and tool geometry to propose “tool integrated assembly interference matrices” (TIAIMs) and a “tool integrated axis-aligned bounding box” (TIAABB) to generate practically feasible assembly sequence plans. Furthermore, the part-concatenation technique is used to determine the best assembly sequence plans for an actual mechanical component. The results show that the proposed approach effectively and efficiently deals with real-life industrial problems.
Clinical stakeholder preferences for paediatric cardiac surgery outcome reporting in Australia and New Zealand
Authors: Suna Jessica M. , Marathe Supreet P. , Venugopal Prem , Justo Robert , Alphonso Nelson , Merlo Gregory , Hall Lisa 
Published: January 2023

AbstractBackground:Outcome reporting is an essential element of quality assurance. Evaluation of the information needs of stakeholders of outcome reporting is limited. This study aimed to examine stakeholder preferences for the content, format, and dissemination of paediatric cardiac surgery performance data in Australia and New Zealand.Methods:Semi-structured interviews were completed with a purposive sample of Queensland stakeholders to evaluate their attitudes and expectations regarding reporting of paediatric cardiac surgery outcomes. The interviews were audio-recorded and transcribed. Two researchers used an interpretive description approach to analyse the transcripts qualitatively.Results:Nineteen stakeholders were interviewed including fifteen clinicians, four parents, one hospital administrator, and one consumer advocate were interviewed. Mortality was highlighted as the area of greatest interest in reports by clinical and consumer groups. The majority preferred hospital rather than individual/clinician-level reporting. Annual reports were preferred by clinicians who requested reports be distributed electronically.Conclusions:The evidence generated from outcome reporting in paediatric cardiac surgery is highly desired by clinicians, administrators, parents, families, and advocacy groups. Clinical users prefer information to assist in clinical decision-making, while families seek personalised information at crucial time points in their clinical journey.
Patient-reported outcome measures in congenital heart surgery: a systematic review
Authors: Francis Jeevan , Prothasis Sneha , George Joseph , Stoica Serban 
Published: January 2023

AbstractBackground:Patient-reported outcome measures are commonly used to evaluate the effectiveness of treatments. CHD remains the most common congenital malformation. There has been a gradual shift in evaluating the outcome of surgery for CHD from mortality to morbidity and now to self-reported outcomes.Aims:We aimed to review studies assessing patient-reported outcome measures as a useful marker of outcome for patients, both children and adults, who underwent surgery for CHD.Methods:A systematic database search was conducted of original articles that explored the application of patient-reported outcome measures in the CHD surgical setting in PubMed and SCOPUS from inception to February 2022.Results:Our search yielded 1511 papers, of which six studies were included in this review after screening abstract and full-text, with a total sample size of 5734 patients. The main areas of discussion were the utility of patient-reported outcome measures, determinants of patient-reported outcome measures, and the need for a congenital cardiac surgery-specific patient-reported outcome measure for paediatric patients and their parents/guardians and adult patients.Conclusion:This systematic review reports the use of patient-reported outcome measures to be a useful indicator to gain insight into the patients’ perspective to provide holistic and patient-centred management. However, further studies are required to assess the utility of patient-reported outcome measures in a congenital cardiac surgical setting.