bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the Organometallic Step: SO2 Insertion into Bi(III)−C(Ph) Bond
Authors: Wong Wing Hei Marco , Guo Xueying , Chan Hok Tsun , Yang Tilong , Lin Zhenyang 
Published: January 2023

AbstractHeavier main‐group element‐catalyzed reactions provide an increasingly attractive tool to perform transformations mimicking the behaviors of transition metal catalysts. Recently, Magre and Cornella reported a Bi‐catalyzed synthesis of aryl sulfonyl fluorides, which involves a fundamental organometallic step of SO2 insertion into the Bi−Ph bond. Our theoretical studies reveal that i) the ability of hypervalent coordination of the Bi(III) center allows facile coordination sphere expansion for the SO2 coordination via one oxygen atom; and ii) the high polarity of the Bi−Ph bond makes the Ph migration from the Bi(III) center feasible. These features enable the heavier main group element to resemble the transition metal having flexibility for ligand association and dissociation. Furthermore, iii) the available π electron pair of the migrating Ph group stabilizes the SO2 insertion transition state by maintaining interaction with the Bi(III) center during migration. The insight helps us better understand the heavier main‐group catalysis.
The opposing impacts of advice use on perceptions of competence
Authors: Palmeira Mauricio , Romero Lopez Marisabel 
Published: January 2023

AbstractWe examine the impact of advice use on perceptions of competence. We propose that advice use sends opposing signals to an advisor regarding the advisee's competence. Greater advice use signals respect for the advisor, which is reciprocated by enhancing competence perceptions. However, greater advice use also indicates a lack of independence in judgment, reducing perceptions of competence. As a result, as advice use increases (i.e., gets closer to the exact advice provided), perceptions of competence first increase but then decrease. We further argue that the impact of advice use on competence is influenced by perceptions of information accessibility, such that when advisor and advisee have access to the same information, lower reliance on advice is more tolerated and less impactful on competence. We show that this effect is conceptually and empirically distinct from advisor's confidence and subsequent preference for advice use.
Agreement between maternal report and medical records on use of medications during early pregnancy in New York
Authors: Howley Meredith M. , Fisher Sarah C. , Fuentes Margueritta A. , Werler Martha M. , Tracy Melissa , Browne Marilyn L. ,   the Birth Defects Study To Evaluate Pregnancy ExposureS
Published: January 2023

AbstractBackgroundStudies evaluating associations between medication use in pregnancy and birth outcomes rely on various sources of exposure information. We sought to assess agreement between self‐reported use of medications during early pregnancy and medication information in prenatal medical records to understand the reliability of each of these information sources.MethodsWe compared self‐reported prescription medication use in early pregnancy to medical records from 184 New York women with deliveries in 2018 who participated in the Birth Defects Study To Evaluate Pregnancy exposureS. We assessed medications used chronically and episodically, and medications within 12 therapeutic groups. We calculated agreement using kappa (κ) coefficients, sensitivity, and specificity. We assessed differences by case/control status, maternal age, education, time to interview, and interview language.ResultsMedications used chronically showed substantial agreement between self‐report and medical records (κ = 0.75, 0.61–0.88), with agreement for therapeutic groups used chronically ranging from κ = 0.61 for antidiabetics to κ = 1.00 for antihypertensives. Prescription medications used episodically showed worse agreement (κ = 0.40, 0.25–0.54), with the lowest agreement for opioid analgesics (κ = 0.20) and anti‐infectives (κ = 0.33). Agreement did not differ by the characteristics examined, although we observed potential differences by interview language.ConclusionsAmong our sample, we observed good agreement between self‐report and medical records for medications used chronically and substantially less agreement for medications used episodically. Differences by source may be due to poor recall in self‐reports, non‐adherence with prescribed medications and lack of complete prescription information within medical records. Limitations should be considered when assessing prescription medication exposures during early pregnancy in epidemiologic studies.
In vitro modeling of liver fibrosis with 3D co‐culture system using a novel human hepatic stellate cell line
Authors: Lee Ho‐Joon , Mun Seon Ju , Jung Cho‐Rok , Kang Hyun‐Mi , Kwon Jae‐Eun , Ryu Jae‐Sung , Ahn Hyo‐Suk , Kwon Ok‐Seon , Ahn Jiwon , Moon Kyung‐Sik , Son Myung Jin , Chung Kyung‐Sook 
Published: January 2023

AbstractHepatic stellate cells (HSCs) play an important role in liver fibrosis; however, owing to the heterogeneity and limited supply of primary HSCs, the development of in vitro liver fibrosis models has been impeded. In this study, we established and characterized a novel human HSC line (LSC‐1), and applied it to various types of three‐dimensional (3D) co‐culture systems with differentiated HepaRG cells. Furthermore, we compared LSC‐1 with a commercially available HSC line on conventional monolayer culture. LSC‐1 exhibited an overall upregulation of the expression of fibrogenic genes along with increased levels of matrix and adhesion proteins, suggesting a myofibroblast‐like or transdifferentiated state. However, activated states reverted to a quiescent‐like phenotype when cultured in different 3D culture formats with a relatively soft microenvironment. Additionally, LSC‐1 exerted an overall positive effect on co‐cultured differentiated HepaRG, which significantly increased hepatic functionality upon long‐term cultivation compared with that achieved with other HSC line. In 3D spheroid culture, LSC‐1 exhibited enhanced responsiveness to transforming growth factor beta 1 exposure that is caused by a different matrix‐related protein expression mechanism. Therefore, the LSC‐1 line developed in this study provides a reliable candidate model that can be used to address unmet needs, such as development of antifibrotic therapies.
New organic ionic plastic crystals based on pyrrolidinium dication for a solid‐phase electrolyte
Authors: Shin Jong Chan , Kim Tae Young , Kim Hwi Jung , Choi U Hyeok , Park Ho Seok , Lee Minjae 
Published: January 2023

AbstractA series of 1,4‐bis(N‐alkylpyrrolidinium)butane salts combined with Br−, I−, PF6−, and Tf2N− anions were newly designed and synthesized. In nonpolar CDCl3 solution, the axial and equatorial proton peaks of the bis‐pyrrolidinium cation ring are distinguished in 1H NMR. Also, the strengths of ion paring could be estimated from the 1H NMR chemical shift changes of the bridge and pyrrolidinium proton peaks. 1,4‐Bis(N‐hepthylpyrrolidinium)butane I− is an organic ionic plastic crystal showing the lowest fusion entropy value (ΔSf = 3.4 J K·mol−1). Softer crystalline morphologies were found by polarized optical microscope images at plastic crystal phase of each sample and the results were corresponding to differential scanning calorimetry results. 1,4‐Bis(N‐ethylpyrrolidinium)butane Tf2N− showed the softest crystal phase. Ionic conductivity changes and electrochemical stabilities of the bis‐pyrrolidinium PF6− and Tf2N− salts were also measured, and they were stable up to 4.3 V (vs. Li/Li+) and expected to be applied as an electrolyte component.
The power of the CEO and environmental decoupling
Authors: Gull Ammar Ali , Hussain Nazim , Khan Sana Akbar , Mushtaq Rizwan , Orij René 
Published: January 2023

AbstractThis paper examines the impact of the power of the chief executive officer (CEO) on environmental decoupling. We define environmental decoupling as a gap between firm's claims about the environmental sustainability and actual environmental sustainability performance. Based on the managerial power theory, we argue that powerful managers are more involved in environmental decoupling and use environmental reporting in a more opportunistic manner than their less powerful peers. We analyse a dataset of 4576 firm‐year observations of US‐listed firms for the period 2002–2017. We find that powerful CEOs decouple firm's environmental performance from environmental reporting. These findings are robust to a battery of analyses and show that powerful CEOs do not show true commitment towards corporate environmental sustainability. The results provide important implications for investors, policymakers and fund managers. Useful future research recommendations are also provided to guide the research in the domain of environmental sustainability.
Developing global supplier competences for supply chain sustainability: The effects of institutional pressures on certification adoption
Authors: Pereira Michele M. O. , Silva Minelle E. , Hendry Linda C. 
Published: January 2023

AbstractDue to institutional pressures faced by companies in their business environment, this paper investigates how sustainability certification adoption affects global suppliers' competences. Using multiple case studies, managers of 20 export‐oriented firms were interviewed, and secondary data were collected and analysed through inductive content analysis. Findings show normative and mimetic pressures as central for sustainability implementation by coffee suppliers. Additionally, we found that as a result of suppliers' sustainability improvement in their own operations, during the certification adoption, new competences emerged going beyond the triple bottom line dimensions, including improvements in aspects of institutional dimension of sustainability. In contrast to previous research in supply chain sustainability that emphasises coercive pressures, this paper demonstrates the role of normative and mimetic institutional pressures in developing new supplier competences. In doing so, we draw on the role of certification adoption in influencing global suppliers and hence sustainability throughout the supply chain.
From linear to a circular economy in the e‐waste management sector: Experience from the transition barriers in the United Kingdom
Authors: Sundar Damini , Mathiyazhagan Kaliyan , Agarwal Vernika , Janardhanan Mukund , Appolloni Andrea 
Published: January 2023

AbstractE‐waste generation is rising apace, and it is estimated that e‐waste production could reach 74.7 Mt by 2030. Hence, it is essential to develop tactics and methodologies for the formal management and treatment of e‐waste. The implementation of the concepts of a circular economy (CE) has been perceived as an efficient methodology for the efficacious management of such waste; however, the transition process from the linear economy to CE still involves several barriers. There are only a few studies that have integrated the concept of CE with e‐waste management for sustainability. This study will focus on the UK's household e‐waste management sector to identify and analyze the key barriers that impede the transition of the UK's e‐waste management sector to the CE model. For this purpose, a team of experts was formulated and their expertise was captured using the Decision‐making trial and evaluation laboratory (DEMATEL) methodology. The DEMATEL technique employs critical evaluation principles, measures the weights of the evaluation criteria, and helps in finding the most critical barriers through a visual structural model. The DEMATEL method also categorizes the factors into cause‐and‐effect groups and utilizes a visualization model to simplify the interdependence and intensity of the impacts of the various factors. The results revealed that the “Lack of processing technologies,” “Lack of returns and profits,” “Lack of expert knowledge,” “Lack of effective guidance and standards for the proper collection methods,” and “Lack of proper knowledge” are the most significant barriers obstructing the adoption of CE in the management of e‐waste in the United Kingdom. Thus, the government needs to take strong actions to give financial support in terms of incentives to the stakeholders for effective e‐waste handling.
5‐step approach for initiating remanufacturing (5AFIR)
Authors: Vogt Duberg Johan , Kurilova‐Palisaitiene Jelena , Sundin Erik 
Published: January 2023

AbstractDespite remanufacturing being a value‐retention process capable of bringing both economic and environmental benefits to original equipment manufacturers (OEMs), the remanufacturing market is small, and the OEM share on the market is even smaller. There are trends in OEMs hesitating to initiate remanufacturing due to the lack of knowledge or often unjustified assumptions about how remanufacturing affects their business‐as‐usual. To further motivate OEMs to initiate remanufacturing, there is a need to extend the remanufacturing initiation theory to showcase how remanufacturing could be initiated in practice. Therefore, this paper aims to describe a remanufacturing initiation and demonstrate the initiation steps for OEMs by developing a remanufacturing initiation framework. The framework is developed based on a remanufacturing initiation led by an OEM of robotic lawn mowers. Based on the case study, a 5‐step approach for initiating remanufacturing (5AFIR) framework—the remanufacturing sapphire—was developed to interpret and visualise the remanufacturing approach taken at the studied OEM. The framework steps consist of the following: (1) Select a product family, (2) involve actors prone to be impacted by remanufacturing, (3) iteratively identify prerequisites and assess the system performance, (4) develop a plan and industrialise remanufacturing, and (5) refine and validate the assessment in Step 3.
Identification of 2‐Methylthio‐methylenethio‐N6‐(cis‐4‐hydroxyisopentenyl)adenosine (msms2io6A37) as a Novel Modification at Adenosine 37 of tRNAs from Salmonella typhimurium
Authors: Libiad Marouane , Douki Thierry , Fontecave Marc , Atta Mohamed 
Published: January 2023

AbstractPost‐transcriptional modifications of tRNA nucleotide are important determinants in folding, structure and function. We have successfully identified and characterized a new modified base named 2‐methylthio‐methylenethio‐N6‐(cis‐4‐hydroxyisopentenyl)adenosine, which is present at position 37 in some tRNAs. We also showed that this new modified adenosine is derived from the known 2‐methylthio‐methylenethio‐N6‐(isopentenyl)adenosine nucleoside by a catalytic cycle of the tRNA‐diiron monooxygenase, MiaE, present in Salmonella typhimurium.
Timing of sedation and patient‐reported pain outcomes during cardiac catheterization: Results from the UNTAP‐intervention study
Authors: Mall Anna , Girton T. Andrew , Yardley Kevin , Ronn Meghan , Cross Elinore , Smith Patrick J. , Rossman Paige , McEwen Tiffany , Ohman E. Magnus , Jones W. Schuyler , Granger Bradi B. 
Published: January 2023

AbstractBackgroundInvasive cardiac catheterization (CC) temporarily increases pain, discomfort, and anxiety. Procedural sedation is deployed to mitigate these symptoms, though practice varies. Research evaluating peri‐procedural patient‐reported outcomes is lacking.Methods and ResultsWe randomized 175 patients undergoing CC to short interval ([SI] group, <6 min) or long interval ([LI] group, ≥6 min) time intervals between initial intravenous sedation and local anesthetic administration. Outcomes included: (1) total pain medication use, (2) patient‐reported and behaviorally assessed pain and (3) patient satisfaction during outpatient CC. Generalized linear mixed effect models were used to evaluate the impact of treatment time interval on total medication utilization, pain, and satisfaction. Among enrollees the mean age was 62 (standard deviation [SD] = 13.4), a majority were male (66%), white (74%), and overweight (mean body mass index = 28.5 [SD = 5.6]). Total pain medication use did not vary between treatment groups (p = 0.257), with no difference in total fentanyl(p = 0.288) or midazolam (p = 0.292). Post‐treatment pain levels and nurse‐observed pain were not statistically significant between groups (p = 0.324 &p = 0.656, respectively. No significant differences with satisfaction with sedation were found between the groups (p = 0.95) Patient‐reported pain, satisfaction and nurse‐observed measures of pain did not differ, after adjustment for demographic and procedural factors. Analyses of treatment effect modification revealed that postprocedure self‐reported pain levels varied systematically between individuals undergoing percutaneous coronary intervention (PCI) (SI = 2.2 [0.8, 3.6] vs. LI = 0.7 [−0.6, 2.0]) compared with participants not undergoing PCI (SI = 0.4 [−0.8, 1.7] vs. LI = 0.7 [−0.3, 1.6]) (p = 0.043 for interaction).ConclusionNo consistent treatment differences were found for total medication dose, pain, or satisfaction regardless of timing between sedation and local anesthetic. Treatment moderations were seen for patients undergoing PCI. Further investigation of how procedural and individual factors impact the patient experience during CC is needed.
Temporary balloon occlusion test can overestimate the risk of acute pulmonary edema after transcatheter atrial septal defect closure
Authors: Nakagawa Koji , Akagi Teiji , Takaya Yoichi , Miki Takashi , Kijima Yasufumi , Nakayama Rie , Toh Norihisa , Nishii Nobuhiro , Nakamura Kazufumi , Morita Hiroshi , Ito Hiroshi 
Published: January 2023

AbstractBackgroundAtrial septal defect (ASD) closure can cause acute pulmonary edema. Before transcatheter closure is performed, temporary balloon occlusion test (BOT) is recommended in patients with left ventricular dysfunction to predict the risk of pulmonary edema. However, the accuracy of BOT has not been verified. This study aimed to compare hemodynamic differences between BOT and transcatheter closure.MethodsA total of 42 patients with a single ASD over age 18 years who underwent BOT before transcatheter ASD closure between October 2010 and May 2020 were analyzed. Pulmonary capillary wedge pressure (PCWP) was measured using a Swan−Ganz catheter placed in the pulmonary artery at baseline, after 10 min of BOT, and after transcatheter closure. Amplatzer septal occluder was used for all transcatheter closures.ResultsMean patient age was 64 ± 18 years (range, 18−78). Mean ASD diameter and pulmonary to systemic flow ratio were 18 ± 5 and 2.8 ± 1.0 mm, respectively. Mean PCWP at baseline, during BOT, and after transcatheter closure was 8.9 ± 2.9, 13.5 ± 4.2, and 9.5 ± 2.6 mmHg, respectively. The difference between BOT and after transcatheter closure values was significant (p < 0.001). During BOT, PCWP increased ≥18 mmHg in 7 patients, whereas after ASD closure, PCWP was <18 mmHg in all 7 and none developed acute pulmonary edema.ConclusionTemporary balloon occlusion of an ASD and transcatheter ASD closure result in different hemodynamic change. BOT overestimates increase of PCWP after transcatheter ASD closure and requires careful interpretation. Well‐designed, larger studies in higher‐risk patients are warranted to verify the clinical implications of BOT in more detail.
A very rare vascular complication of the Edwards expandable eSheath during transcatheter aortic valve replacement
Authors: Savvoulidis Panagiotis , Nadir Adnan M. , Mechery Anthony , Doshi Sagar N. 
Published: January 2023

AbstractTranscatheter aortic valve replacement (TAVR) has revolutionized the management of severe symptomatic aortic valve stenosis. TAVR is now indicated as an alternative to surgical replacement in a wide risk profile ranging from high to low surgical risk. Although vascular complications have decreased in frequency over time, with the introduction of lower profile delivery systems and sheaths, they remain one of the most frequently encountered and serious complications of TAVR. Patient‐specific predisposing factors have been well characterized. However, much less is known about device‐specific complications. Awareness of the possible device‐related complications may lead to earlier identification, prompt management, and better outcomes. We report a previously unreported complication of the Edwards expandable eSheath that lead to avulsion of the external iliac artery following successful TAVR with a 29‐mm Edwards Sapien 3 transcatheter heart valve. Bleeding was promptly controlled with an occlusion balloon and emergency surgical repair was required with a favorable outcome.
Electrochemical oxidation of the increasingly used disinfectant benzalkonium chloride
Authors: Hughes Kara , Han Weiqi , Yargeau Viviane , Omanovic Sasha 
Published: January 2023

AbstractBenzalkonium chloride (BAC) is a key ingredient in many cleaning and disinfectant products due to it being an effective antiviral and biocidal agent. Because of its prolific use, especially following the recent global COVID pandemic, increased levels of BAC have been found in the environment, in particular, in wastewater, where it has negative impacts due to its toxicity. This necessitates an effective treatment for BAC in wastewater to reduce its toxicity. In this work, electrochemical oxidation of BAC on a boron‐doped diamond anode was studied to successfully remove BAC. The electrochemical measurements performed at different current densities confirmed that BAC was completely oxidized within 20 min of treatment at 50 mA/cm2. However, chemical oxygen demand (COD) measurements showed that around 50% of the initial BAC was completely mineralized after 1 h of degradation at 50 mA/cm2, while the remaining electrooxidation of BAC resulted in the production of transformation products.
Energy efficiency optimization routing decision scheme in three‐dimensional wireless ad hoc network
Authors: Liu Dakun , Chen Guifen , Wang Yijun 
Published: January 2023

SummaryIn recent years, many realistic wireless ad hoc networks (WANETs) have taken on three‐dimensional characteristics due to the implementation of various structures such as viaducts, tunnels, and overpasses. An increasing amount of work has also been devoted to studying the challenges posed by 3D vanet scenarios. And research on routing methods for 3D vanet scenarios is a hot topic. However, the three‐dimensional scene routing decision schemes have some problems, such as low data transmission efficiency, high energy consumption, and low end‐to‐end delays. Therefore, an energy efficiency optimization routing decision system is proposed based on the establishment of a three‐dimensional Voronoi polygon topology model. First, we define a node state‐related attribute parameter that determines whether the source node and the forward node are linked. The data forwarding node is determined by comparing attribute differences. Then, a power control mechanism based on received signal strength is proposed to solve the energy consumption, which includes deterministic and random parts. Finally, the specific state of the network node is monitored by comparing the attribute decision matrix to ensure basic maintenance of network operation and improve network transmission reliability. The simulation results show that the proposed scheme not only ensures the communication performance index in WANETs but also improves the reliability of the network.