bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rescue therapy for local tumor progression after radiofrequency ablation of small hepatocellular carcinoma: a comparison between repeated ablation and transcatheter arterial chemoembolization
Authors: Cha Dong Ik , Lee Min Woo , Ahn Soo Hyun , Song Kyoung Doo , Kang Tae Wook , Sinn Dong Hyun , Rhim Hyunchul 
Published: April 2023

Objective: To compare the therapeutic outcomes of repeated radiofrequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) as rescue therapy for the treatment of local tumor progression (LTP) after initial RFA for hepatocellular carcinoma (HCC). Methods: This retrospective study evaluated 44 patients who had LTP as initial tumor recurrence after RFA and underwent repeated RFA (n = 23) or TACE (n = 21) for local disease control. Local disease control and overall survival rates were evaluated using the Kaplan–Meier method. A Cox proportional-hazards regression model was used to identify the independent prognostic factors. The local disease control rate after the first rescue therapy and the number of rescue therapies applied until the last follow-up were also evaluated. Results: Local disease control after rescue therapy for LTP was significantly higher with repeated RFA than with TACE (p < 0.001). Treatment type was a significant factor for local disease control (p < 0.001). The overall survival rates after rescue therapy were not significantly different between the two treatments (p = 0.900). The local disease control rate after the first rescue therapy was significantly higher with RFA than with TACE (78.3% vs 23.8%, p < 0.001). The total number of rescue therapies applied was significantly higher in the TACE group than that in the repeated RFA group (median 3 vs 1, p < 0.001). Conclusion: Repeated RFA as rescue therapy for LTP after initial RFA for HCC was more efficient and had significantly better local disease control than TACE. Advances in knowledge: Even if LTP occurs after initial RFA, it should not be considered a failure of RFA, and repeated RFA should be performed over TACE if possible for more effective local disease control.
Oral hygiene as a cardiovascular risk factor - review of the literature
Authors: Chiżyński Adam , Łęgocka Weronika , Andryszczak Paweł 
Published: April 2023

Introduction and Objective. Cardiovascular diseases are the main cause of death in Poland and around the world. An important aspect of managing patients with cardiovascular diseases is their proper diagnosis and treatment. An important element is also the prevention of cardiovascular diseases. Prevention of the occurrence of cardiovascular diseases mentioned above consists of the elimination of so-called cardiovascular risk factors. A relatively unknown risk factor for cardiovascular disease is the lack of oral hygiene. The authors of the work analyze what elements are related to the lack of oral hygiene affect the cardiovascular risk and try to present the mechanisms of the oral cavity condition that may affect the cardiovascular system.

Review Methods. A review of the recent literature was conducted using PubMed, Google Scholar databases.

Brief description of the state of knowledge. The oral cavity is a site colonised by many species of microorganisms.Bacteria from periodontal pockets can travel to other systems as well as enter the bloodstream, and that way to distant organs. A normal endocardial endothelium provides a barrier for bacteria and prevents colonisation and the development of inflammation. However, in cases where it is damaged, it can provide a gateway for microorganisms to infect the valve, which may lead to the development of infective endocarditis.

Summary. In case of periodontitis in patient with ischemic heart disease, myocardial infarction or stroke, active dental or periodontal treatment should be undertaken. Bacteria from periodontal pockets can travel to other systems causing pathological changes in them.

Key words

Oral hygiene, periodontitis, infective endocarditis
High prevalence of malaria in pregnancy among women attending antenatal care at a large referral hospital in northwestern Uganda: A cross-sectional study
Authors: Mangusho Caleb , Mwebesa Edson , Izudi Jonathan , Aleni Mary , Dricile Ratib , Ayiasi Richard M. , Legason Ismail D. 
Published: April 2023

Background
Malaria in pregnancy contributes to substantial morbidity and mortality among women in Uganda. However, there is limited information on the prevalence and factors associated with malaria in pregnancy among women in Arua district, northwestern Uganda. We, therefore, assessed the prevalence and factors associated with malaria in pregnancy among women attending routine antenatal care (ANC) clinics at Arua regional referral hospital in north-western Uganda.

Methods
We conducted an analytic cross-sectional study between October and December 2021. We used a paper-based structured questionnaire to collect data on maternal socio-demographic and obstetric factors and malaria preventive measures. Malaria in pregnancy was defined as a positive rapid malarial antigen test during ANC visits. We performed a modified Poisson regression analysis with robust standard errors to determine factors independently associated with malaria in pregnancy, reported as adjusted prevalence ratios (aPR) and 95% confidence intervals (CI).

Results
We studied 238 pregnant women with a mean age of 25.32±5.79 years that attended the ANC clinic, all without symptomatic malaria. Of the participants, 173 (72.7%) were in their second or third trimester, 117 (49.2%) were first or second-time pregnant women, and 212 (89.1%) reported sleeping under insecticide-treated bednets (ITNs) every day. The prevalence of malaria in pregnancy was 26.1% (62/238) by rapid diagnostic testing (RDT), with the independently associated factors being daily use of insecticide-treated bednets (aPR 0.41, 95% CI 0.28, 0.62), first ANC visit after 12 weeks of gestation (aPR1.78, 95% CI 1.05, 3.03), and being in the second or third trimester (aPR 0.45, 95% CI 0.26, 0.76).

Conclusion
The prevalence of malaria in pregnancy among women attending ANC in this setting is high. We recommend the provision of insecticide-treated bednets to all pregnant women and early ANC attendance to enable access to malaria preventive therapy and related interventions.
DNA Barcoding and Morphological Characters of Two Trevally Fish species (Caranx Spp.) Collected from Youtefa Bay, Papua, Indonesia
Authors: Kainama Tamara Louraine Jeanette , Wijayanti Diah Permata , Sabdono Agus , Dirgantara Dio 
Published: April 2023

Trevally fish (Caranx spp,) or Kuwe fish (local name) are small pelagic fish that are mostly caught in the waters of Youtefa Bay. There are two types of Kuwe fish that are difficult to distinguish due to morphological similarities. These Kuwe fish have no scientific species identification so they have several different local names. Accordingly, it is necessary to identify and find out the proper naming of the two Kuwe fish. DNA barcoding is a technique used to speed up and simplify the process of identifying organisms. Hence, the purpose of this research was to identify the proper scientific name of the two Kuwe species in Youtefa Bay waters, as well as the kinship between these two types by applying a DNA barcoding technique. Nineteen Kuwe fish were sampled at Youtefa Bay, Jayapura, Papua in July 2022. Samples were studied morphologically, then carried directly to the Integrated Laboratory of Diponegoro University for molecular studies. DNA extraction, amplification, and DNA sequencing were carried out to further validate the species’ identification. The results showed that in the initial assessment of the specimens using taxonomic keys, 10 specimens were identified as Caranx sexfasciatus and 9 specimens were identified as Caranx tille. The relationship between length and weight of C. sexfasciatus and C. tille have resulted in b = 2.5754 with R2 = 0.8564 and = 1.7119 with R2 = 0.6705, respectively. All identifications were confirmed as correct based on BLASTn results. The BLAST analysis demonstrated that 10 samples were closely related to C. sexfasciatus (99%-100% in similarity) and 9 samples were similar to C. tille (97%- 99%). The genetic distance between individuals in C. sexfasciatus and C. tille has a value ranging from 0% - 0.2%, and the phylogenetic tree exposed that the two species are included in different clades. This study revealed that there are two species of Kuwe fish (C. sexfasciatus and C. tille) in Youtefa Bay, Papua, Indonesia.
PRODUKSI DAN UJI PERFORMANSI MESIN PEMBUAT BUBUR KERTAS KAPASITAS 960 LITER/JAM
Authors: Supraptono Supraptono , Kriswanto Kriswanto , Rozikin Ahmad , Fatoni Muhamad Hasan , Hasyim Fuad , Wijayanto Bagus 
Published: April 2023

Tujuan penelitian ini adalah memproduksi mesin pembubur kertas dan menganalisis hasil pengujian performansi mesin bubur kertas dengan variasi jenis kertas dan lama waktu produksi. Penelitian ini merupakan penelitian terapan dimana pembuatan mesin menggunakan proses manufaktur sedangkan pengujian performansi mesin menggunakan metode eksperimen. Metode ekperimen dalam penelitian ini dengan melakukan uji coba performansi mesin bubur kertas dimana variabel bebas adalah jenis bahan kertas, dan waktu produksi, sedangkan variabel terikatnya adalah ukuran partikel, dan kapasitas produksi. Hasil uji performansi selanjutnya diamati menggunakan pemeriksaanmakroscopik menggunakan aplikasi infinity analyz. Hasil penelitian ini mendapatkan prototype mesin pembuat bubur kertas kapasitas 6 liter/jam dengan spesifikasi: panjang 1,29 m; lebar 0.646 m; tinggi 1,119 m; daya 1,5 HP. pengujian kapasitas produksi bubur kertas pada variasi waktu 3 menit yaitu sebesar 60 kg/jam, sedangkan hasil pemeriksaan partikel makrodidapatkan ukuran partikel besar lebih dari 1 mm hanya terdapat pada beberapa titik (minor) yang mungkin disebabkan dari bubur kertas yang terlempar ke dinding atas tabung sehinggatidak terproses.
Analisis Variasi Kecepatan Potong Dan Kedalaman Potong Terhadap Nilai Kekasaran Permukaan Dan Getaran Pada Pembubutan Silindris Material Baja ST 60
Authors: Rosandi Anwar , Sumbodo Wirawan , Yudiono Heri , Kriswanto Kriswanto 
Published: April 2023

Mesin bubut konvensional masih sering dipakai, tetapi permasalahannya mesin bubut konvensional sulit mendapatkan kualitas produk yang benar-benar baik (dimensi geometri, kekasaran permukaan dan reflektif geometri yang sesuai) Disebabkan karena faktor dari manusia, parameter pemotongan yang digunakan dan faktor kondisi mesin itu sendiri. Tujuan dalam penelitian ini untuk mengetahui untuk mengetahui seberapa besar pengaruh kecepatan potong dan kedalaman potong terhadap getaran dan kekasaran permukaan pada proses pembubutan silindris. Penelitian ini termasuk jenis penelitian kuantitatif menggunakan metode eksperimen. Untuk pengumpulan data menggunakan teknik metode observasi dan dokumentasi. Teknik analisis data menggunakan teknik analisis regresi. Hasil penelitian yang telah didapatkan, diketahui nilai getaran mesin yang tertinggi adalah 5.4 m/s2 dan yang terendah adalah 1.8 m/s2. Nilai getaran rumah pahat yang paling tinggi adalah 5 m/s2 dan yang terendah adalah 1 m/s2. Dan untuk yang kekasaran permukaan yang paling tinggi adalah 5.0 Âµm dan yang terendah adalah 2.33 Âµm. Serta dapat disimpulkan bahwa semakin tinggi kecepatan potong dan kedalaman potong maka getaran mesin, getaran rumah pahat dan kekasaran akan semakin tinggi.
Take the plunge
Authors: Garcia Rosa Rodrigo 
Published: April 2023

Phraseology has proven to be an important aspect of languages; as such, linguistic theories were forced to reshape their explanatory tools so as to incorporate this important aspect of language to their descriptive models. In light of this, analogous areas such as first and second language acquisition theories have all acknowledged the importance of speakers’ phraseological knowledge in real communication, both in L1 and L2 acquisition settings and in general language use. Nevertheless, despite being a relatively well-known phenomenon in theoretical studies, little has been said about the relationship between phraseology and syntax. More specifically, the idea of using phraseology as a starting point for the teaching of schematic grammatical structures seems to be a promising area of application and investigation. This paper aims to contribute to this area by presenting some ideas on how phraseology can be used as a springboard for the teaching of grammar.
EFFECT OF A SCANDIUM ADDITION ON ANODIZING AlMg ALLOYS
Authors: Karpe Blaž , Kern Katarina , Kovač Janez , Klanjšek Gunde Marta , Nagode Aleš , Bizjak Milan , Zorc Matija 
Published: April 2023

Scandium (Sc) is known to be one of the most effective alloying elements of aluminum alloys. The only drawback is its high price, but that could change quickly due to the promising results of recent research on its extraction. However, the data on how it affects anodic oxidation are very scarce. In this research, we analyzed how a micro-addition of Sc to the AlMg alloy affects the growth mechanism and properties of the protective aluminium oxide layer depending on the anodization parameters. For comparison, alloy AA5083 with a similar magnesium content was also anodized with the same anodizing parameters. In all experiments, sulfuric acid (VI) with concentrations of 1.72 M or 2.2 M at temperatures of 21 °C or 35 °C was used as the electrolyte. Potentiostatic (18 V) and galvanostatic (20 mA/cm2) anodizing methods were applied. The results (SED-EDS) show that scandium is uniformly intercalated in the matrix of the oxide layer and decreases its resistivity, which increases the oxide growth rate during potentiostatic anodizing and decreases the pore density and pore diameters during galvanostatic anodizing. Moreover, it increases the mobility of cations through the oxide layer, thus accelerating the oxidation reaction in concentrated sulfuric acid electrolytes. On the other hand, the increased cation mobility considerably increases the sensitivity to the temperature of the electrolyte, which can change the growth mechanism of the oxide layer and thus its morphology.
MULTI-ELECTRODE TRANSCUTANEOUS ELECTRICAL STIMULATION OF THE HUMAN EXTERNAL EAR
Authors: Pečlin Polona , Rozman Janez , Janež Renata , Emri Anja , Ribarič Samo , Mirković Tomislav 
Published: April 2023

This article reviews the development of a new concept for crafting and testing a multi-electrode set-up for selective transcutaneous auricular nerve stimulation (tANS) using particular superficial regions of the external ear (EE). The purpose of the work is to assess the mechanical properties of the set-up to ensure the optimum conditions for the users, and to test the ability to affect vital physiological functions. The set-up consisted of eight cap-like platinum simulating cathodes (S = 14.58 mm2) that were embedded in the left and right silicone ear plugs. The plugs were mounted onto the frame of dummy headphones and inserted into the EE, while a common anode (anode) (S = 4500 mm2) was placed at the nape of the neck. The mechanical performance was assessed by measuring the axial force Fx acting on each cathode against the bending of the dummy headphone frame while simulating the conditions of the set-up being mounted onto the head. The functionality was tested by applying stimuli onto four predefined sites at the EE to modify particular vital physiological functions of female volunteers. The preliminary results show that during the tANS, the bi-nasal respiration became shorter but more frequent with steeper inspiration and a lower airflow. The results also show that during the tANS, the heart rate was slightly diminished along with the respiratory sinus arrhythmia. Finally, a dicrotic notch within the toe photoplethysmogram was masked by the waves with a frequency of approximately 300 min–1. The presented work has implications for the multi-electrode set-up design and the prediction of efficient tANS used to modify physiological functions.
Computational Approach for Mining Simple Sequence Repeats in Expressed Sequence Tags
Authors: Saini Umang , Bharti P K , Husain Akhtar 
Published: April 2023

Expressed sequence tags, the short sequences of cDNA are mined for identifying and characterizing simple sequence repeats for studying genetic variations. Web-based tools due to lack of server maintenance, become unusable; also few available stand-alone tools lack processing adequateness. Therefore with the intent to process multiple expressed sequence tag files without size limitations, proper validations, and the ability to retrieve more genome-related features; a simple to use, speed efficient portable standalone tool has been developed. The algorithm is implemented in Java using microsatellite search algorithm, with dictionary-based approach MISA – Perl script, called via command line for data mining. Another parallel module retrieves additional information from GenBank files. In the pipeline primer 3 was invoked for designing batch primers. This algorithm with an extended interface in Java Net Beans provides naïve users with a simple interactive tool for mining microsatellites, statistical analysis, and primer designing on one platform in the form of a stand-alone application. The number of repeats/ interruptions parameters can be reset through the graphical interface. This tool has interactive modules with proper validations; batch processing and cost-effective analysis of tandem repeats as compared to peers, the source code can be upgraded in the future.
The effect of video assisted teaching programme on knowledge regarding prevention and management of black fungus among staff nurse
Authors: Khuntia Sudhir Kumar , Thakur Reena 
Published: April 2023

A dangerous fungal infection that has recently emerged as a hazard for COVID-19 survivors, mucormycosis was first identified in Bangladesh on May 8, 2021, and is now commonly referred to as "black fungus" in the COVID-19 period. During the COVID-19 epidemic, black fungi are eighty times more common in India. The COVID-19 black fungi has spread to numerous nations, including Bangladesh, Pakistan, Russia, Iran, and Brazil. Being physically close to India, Bangladesh is concerned about the worrisome rise in COVID-19-related black fungus infections in India, which have a high fatality rate of about 50%. Pre-experimental design with one-group pre-test and post-test study method was used to examine staff nurses' understanding of black fungus avoidance and control; the participants were chosen through handy sampling. The data collected was analyzed using descriptive and inferential statistics in terms of frequency, mean, standard deviation, and associated by chi square test. Among 60 staff nurse in pre-test, 29 (48.33%) have poor knowledge, 27 (45%) have average knowledge, 4 (6.67%) having good, and in post-test 44 (33.33%) having good knowledge, 16 (26.67%) having average knowledge.Under Pre-test the Mean of the Scores was 8.3 (55.33%) under the Post- test the Mean was observed as 12.2 (81.33%).
Body fat percentage utility over lipid profile as marker of dyslipidemia in type 2 diabetes mellitus
Authors: Aruna Vaddiparti , Chowdeswari N , Murthy Tummalagunta Nrusimha 
Published: April 2023

Obesity, Metabolic syndrome and dyslipidaemia are gaining prevalence as noncommunicable causes of health hazards like CVD, IHD. National surveys under the leadership of ICMR were in progress to detect causes of high fat content in the body and means to detect the same early are underway. We made an attempt to know the importance of body fat percentage in Type 2 Diabetes Mellitus as marker of dyslipidaemia. : To study relationship of BMI, body fat percent (BFP) and lipid profile in type 2 Diabetes Mellitus.: 35 Type2DM (normotensive) subjects in the age group of 30-55yrs in both sexes and 35 age & sex matched healthy controls were selected for the study after obtaining informed consent. Anthropometric data was recorded. Their fasting venous blood samples were analysed for sugar & Lipid profile ERBA Chem 5 semiautoanalyser. BMI and BFP were calculated.: BFP was well above normal levels in both cases and controls (38.03±12.13 &44.9±7.66 respectively) for the age group of 30-55yrs normal limits being 19,3% -26.3% according to Jackson & Pollard. The mean BMI of cases was 33.22±8.59 compared to 37.07±4.1 of controls, indicating both groups were class II obese individuals. BMI & BFP showed statistically significant correlation between cases and controls by Student’s ‘t’ test (p &#60;0.009 & &#60;0.003 respectively) and also within the groups (P &#60;0.00001) by way of ANOVA. Analysis was done to detect gender difference. In males and females there was strongly positive correlation of BMI as detected by Pearson’s Correlation coefficient (r = 0.914 & 0.976). TC, TG & HDL showed weak positive correlation with BMI & BFP in diabetic subjects, whereas LDL correlated negatively with BMI & BFP.: We could not conclude superiority of BFP over BMI in assessing dyslipidaemia. Nevertheless, the study can be done using other methods of evaluation of BFP in T2DM like ultrasound, computerised tomography.
Role of circulating C-peptide in the Indian population with Type 2 diabetics with nephropathy: A triangular relationship between C-peptide, HbA1C and microalbuminuria
Authors: Ganesan Vinothkumar , Vijayam Balaji , Balaji Taarika , Balaji Madhuri S , Veerasamy Seshiah 
Published: April 2023

C-peptide levels can initially be normal or increased in type 2 diabetes mellitus (T2DM), which is connected to insulin resistance; however, as the condition progresses, these levels may fall. According to studies, kidney failure has diabetes as its primary cause, accounting for 44% of all new cases. In addition, it's critical to strictly regulate blood sugar levels and lower protein intake. Along with insulin, the pancreas produces a molecule called C-peptide. The hormone insulin regulates the body's glucose levels. A total of 300 subjects divided into 150 CKD progression diabetic nephropathy and 150 non-progressions diabetic nephropathy based on clinical parameter assessment. All patients had their body weight and body mass index (BMI) assessed. Fasting serum C peptide, HbA1C, serum creatinine, blood urea nitrogen, urine albumin, and creatinine were among the laboratory tests performed. Using the MDRD algorithm, creatinine clearance was determined from serum creatinine value. The parameters were statistically compared with respective subjects. The small case-control study found a no relationship between serum C-peptide levels and both microalbuminuria and HbA1C. Risk of microalbuminuria may be higher in patients with low serum C peptide levels. In patients with T2DM, replacing C-peptide and administering insulin may be useful. The possibility that C-peptide may play a part in the prevention and treatment of diabetic nephropathy will need to be investigated in studies including longer-term C-peptide administration.