bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Patterned Knitted Fabric with Reversible Gating Stability for Dynamic Moisture Management of Human Body
Authors: Lin Yanyan , Cheng Ningbo , Meng Na , Wang Chao , Wang Xianfeng , Yu Jianyong , Ding Bin 
Published: July 2023

AbstractDeveloping dynamic moisture management of textiles is of great significance for smart clothing. However, the current pore‐actuated fabric suffers from macro‐dimensional deformation in response. Moreover, the fabric is limited in its ability to control the direction and speed of sweat transfer. Herein, a patterned cotton fabric (PCF) is proposed by constructing thermal‐triggered transmission channels on the knitted hydrophobic cotton. The resultant fabric can switch the mode of channels spontaneously depending on ambient temperature. When PCF is exposed to the cold environment, the channels are “closed”, which prevents the intrusion of rainwater, reducing moisture permeability (12.1% lower than cotton) and maintaining human body temperature (0.8 °C higher than cotton). When the weather gets hot, channels are “open”, allowing for efficient transportation of water vapor (18.0% higher than cotton) and directional sweat transportation. This design allows adaptive water vapor gating to synergistically occur with directional liquid transport, maximizing personal warming (when cold and raining) and cooling (when hot and sweating).
Mimosa‐Inspired High‐Sensitive and Multi‐Responsive Starch Actuators
Authors: Hu Hao , Nie Mingzhe , Galluzzi Massimiliano , Yu Xuefeng , Du Xuemin 
Published: July 2023

AbstractArtificial intelligent actuators are extensively explored for emerging applications such as soft robots, human‐machine interfaces, and biomedical devices. However, intelligent actuating systems based on synthesized polymers suffer from challenges in renewability, sustainability, and safety, while natural polymer‐based actuators show limited capabilities and performances due to the presence of abundant hydrogen‐bond lockers. Here this study reports a new hydrogen bond‐mediated strategy to develop mimosa‐inspired starch actuators (SA). By harnessing the unique features of gelatinization and abundant hydrogen bonds, these SA enable high‐sensitivity and multi‐responsive actuation in various scenarios. The non‐gelatinized SA can be irreversibly programmed into diverse shapes, such as artificial flowers, bowl shapes, and helix structures, using near‐infrared light. Furthermore, the gelatinized SA exhibit reversibly multi‐responsive actuation when exposed to low humidity (10.2%), low temperature (37 °C), or low‐energy light (0.42 W cm−2). More importantly, the SA demonstrate robust applications in smart living, including artificial mimosa, intelligent lampshade, and morphing food. By overcoming the hydrogen‐bond lockers inherent in natural polymers, SA open new avenues for next‐generation recyclable materials and actuators, bringing them closer to practical applications.
Interfacial Microenvironment Modulation Boosts Efficient Hydrogen Evolution Reaction in Neutral and Alkaline
Authors: Yang Weiwei , Li Mengyuan , Zhang Bikun , Liu Yazi , Zi Jiangzhi , Xiao Han , Liu Xinyang , Lin Jingkai , Zhang Huayang , Chen Jian , Wan Zhengfen , Li Zhen , Li Guisheng , Li Hexing , Lian Zichao 
Published: July 2023

AbstractThe design of highly efficient and stable electrocatalysts in hydrogen evolution reaction over a wide range of pH, especially in neutral or alkaline conditions, is of great significance but remains· challenging. Herein, a family of single‐atoms and clusters inside the N‐doped porous carbon matrix (NDPCM) are encapsulated. Specifically, the single‐atom platinum (PtSA) and cluster platinum (PtC) in NDPCM exhibited ultralow overpotentials of 20 and 14 mV at −10 mA cm−2 under neutral and alkaline conditions, respectively and superior long‐term durability. Theoretical calculations and operando Raman measurements revealed that the coexistence of PtSA and PtC can provide multiple H adsorption sites, contributing to the extremely low |ΔGH*| of H adsorption and constructing a local acidic microenvironment to trigger a unique H3O+‐induced water reduction in neutral and alkaline conditions This unique configuration significantly promotes the catalytic activity and opens a new avenue for the crafted design of electrocatalysts.
A Universal Descriptor in Determining H2 Evolution Activity for Dilute Aqueous Zn Batteries
Authors: Miao Licheng , Xiao Zhe , Shi Dongjie , Wu Mingli , Liu Dongming , Li Yun , Liu Xueping , Sun Yiling , Zhong Shengkui , Qian Zhengfang , Wang Renheng 
Published: July 2023

AbstractLarge‐scale energy storage with aqueous Zn batteries (AZBs) have bright future, but their practical application is impeded by H2 evolution reaction (HER), which results in poor stability of Zn–metal anodes. Here, using linear sweep voltammetry in dilute salt aqueous electrolytes, it is discovered that as the salt concentration decreases, HER is gradually suppressed, which is contrary to prior beliefs. Combining calculations and experiments, it is demonstrated that HER derives predominantly from the sum of Zn2+‐solvated water rather than the average amount of water in the Zn2+‐solvation structural unit or free water without interaction with Zn2+, which answers the puzzle from above. This result, which differs fundamentally from the previous understandings, sheds new light on the mysterious role of water chemistry in controlling HER and contributes to a more rational design of advanced electrolytes for AZBs.
Anti‐Pan‐Rspo Chimeric Protein‐Conjugated Albumin Nanoparticle Provides Promising Opportunities in Cancer Targeted Therapy
Authors: Zheng Shaoqin , Zhang Xi , Pang Zhongqiu , Liu Jidong , Liu Siyu , Sheng Ren 
Published: July 2023

AbstractRspos (R‐spondins) belong to a family of secreted proteins that causes various cancers via interacting the corresponding receptors. However, targeted therapeutic approaches against Rspos are largely lacking. In this study, a chimeric protein Rspo‐targeting anticancer chimeric protein (RTAC) is originally designed, engineered, and characterized. RTAC shows satisfactory anticancer effects through inhibition of pan‐Rspo‐mediated Wnt/β‐catenin signaling activation both in vitro and in vivo. Furthermore, a conceptually novel antitumor strategy distinct from traditional drug delivery systems that release drugs inside tumor cells is proposed. A special “firewall” nano‐system is designed to enrich on tumor cell surface and cover the plasma membrane, rather than undergoing endocytosis, to block oncogenic Rspos from binding to receptors. Cyclic RGD (Arg‐Gly‐Asp) peptide‐linked globular cluster serum albumin nanoparticles (SANP) are integrated as a vehicle for conjugating RTAC (SANP‐RTAC/RGD) for tumor tissue targeting. These nanoparticles can adhere to the tumor cell surface and enable RTAC to locally capture free Rspos with high spatial efficiency and selectivity to antagonize cancer progression. Therefore, this approach offers a new nanomedical anticancer route and obtains the “dual‐targeting” capability for effective tumor clearance and low potential toxicity. This study presents a proof‐of‐concept for anti‐pan‐Rspo therapy and a nanoparticle‐integrated paradigm for targeted cancer treatment.
Plasma‐driven CO2 hydrogenation to CH3OH over Fe2O3/γ‐Al2O3 catalyst
Authors: Meng Shengyan , Wu Liang , Liu Miao , Cui Zhaolun , Chen Qian , Li Shangkun , Yan Jiahui , Wang Li , Wang Xinkui , Qian Ji , Guo Hongchen , Niu Jinhai , Bogaerts Annemie , Yi Yanhui 
Published: July 2023

AbstractWe report a plasma‐assisted CO2 hydrogenation to CH3OH over Fe2O3/γ‐Al2O3 catalysts, achieving 12% CO2 conversion and 58% CH3OH selectivity at a temperature of nearly 80°C atm pressure. We investigated the effect of various supports and loadings of the Fe‐based catalysts, as well as optimized reaction conditions. We characterized catalysts by X‐ray powder diffraction (XRD), hydrogen temperature programmed reduction (H2‐TPR), CO2 and CO temperature programmed desorption (CO2/CO‐TPD), high‐resolution transmission electron microscopy (HRTEM), scanning transmission electron microscopy (STEM), x‐ray photoelectron spectroscopy (XPS), Mössbauer, and Fourier transform infrared (FTIR). The XPS results show that the enhanced CO2 conversion and CH3OH selectivity are attributed to the chemisorbed oxygen species on Fe2O3/γ‐Al2O3. Furthermore, the diffuse reflectance infrared Fourier transform spectroscopy (DRIFTs) and TPD results illustrate that the catalysts with stronger CO2 adsorption capacity exhibit a higher reaction performance. In situ DRIFTS gain insight into the specific reaction pathways in the CO2/H2 plasma. This study reveals the role of chemisorbed oxygen species as a key intermediate, and inspires to design highly efficient catalysts and expand the catalytic systems for CO2 hydrogenation to CH3OH.
Mapping spatial morbidity patterns for bronchiolitis related to socioeconomic estimators: A spatial epidemiology approach to identify health disparities in Puerto Madryn, Argentina
Authors: Pazos Bruno A. , Morales Arturo L. , Ramallo Virginia , González‐José Rolando , de Azevedo Soledad , Taire Damián L. 
Published: July 2023

AbstractObjectivesTo describe the frequency of hospitalizations of infants under 1 year of age with bronchiolitis in Puerto Madryn, Argentina, and to study the spatial distribution of cases throughout the city in relation to socioeconomic indicators. To visualize and better understand the underlying processes behind the local manifestation of the disease by creating a vulnerability map of the city.MethodsWe performed a cross‐sectional study of all patients discharged for bronchiolitis from the local public Hospital in 2017, considering length of hospital stay, readmission rate, patient age, home address and socioeconomic indicators (household overcrowding). To understand the local spatial distribution of the disease and its relationship to overcrowding, we used GIS and Moran's global and local spatial autocorrelation indices.ResultsThe spatial distribution of bronchiolitis cases was not random, but significantly aggregated. Of the 120 hospitalized children, 100 infants (83.33%) live in areas identified as having at least one unsatisfied basic need (UBN). We found a positive and statistically significant relationship between frequency of cases and percentage of overcrowded housing by census radius.ConclusionsA clear association was found between bronchiolitis and neighborhoods with UBNs, and overcrowding is likely to be a particularly important explanatory factor in this association. By combining GIS tools, spatial statistics, geo‐referenced epidemiological data, and population‐level information, vulnerability maps can be created to facilitate visualization of priority areas for development and implementation of more effective health interventions. Incorporating the spatial and syndemic perspective into health studies makes important contributions to the understanding of local health‐disease processes.
Low‐intensity pulsed ultrasound alleviates doxorubicin‐induced cardiotoxicity via inhibition of S100a8/a9‐mediated cardiac recruitment of neutrophils
Authors: Zhu Hong , He Min , Wang Yong‐Li , Zhang Yuanxin , Dong Jingsong , Chen Bo‐Yan , Li Yu‐Lin , Zhou Lu‐Jun , Du Lin‐Juan , Liu Yuan , Zhang Wu‐Chang , Ta Dean , Duan Sheng‐Zhong 
Published: July 2023

AbstractDoxorubicin (DOX)‐induced cardiotoxicity limits its broad use as a chemotherapy agent. The development of effective and non‐invasive strategies to prevent DOX‐associated adverse cardiac events is urgently needed. We aimed to examine whether and how low‐intensity pulsed ultrasound (LIPUS) plays a protective role in DOX‐induced cardiotoxicity. Male C57BL/6J mice were used to establish models of both acute and chronic DOX‐induced cardiomyopathy. Non‐invasive LIPUS therapy was conducted for four consecutive days after DOX administration. Cardiac contractile function was evaluated by echocardiography. Myocardial apoptosis, oxidative stress, and fibrosis were analyzed using terminal deoxynucleotidyl transferase‐mediated dUTP nick end labelling (TUNEL) staining, dihydroethidium (DHE) staining, and picrosirius red staining assays. RNA‐seq analysis was performed to unbiasedly explore the possible downstream regulatory mechanisms. Neutrophil recruitment and infiltration in the heart were analyzed by flow cytometry. The S100a8/a9 inhibitor ABR‐238901 was utilized to identify the effect of S100a8/a9 signaling. We found that LIPUS therapy elicited a great benefit on DOX‐induced heart contractile dysfunction in both acute and chronic DOX models. Chronic DOX administration increased serum creatine kinase and lactate dehydrogenase levels, as well as myocardial apoptosis, all of which were significantly mitigated by LIPUS. In addition, LIPUS treatment prevented chronic DOX‐induced cardiac oxidative stress and fibrosis. RNA‐seq analysis revealed that LIPUS treatment partially reversed alterations of gene expression induced by DOX. Gene ontology (GO) analysis of the downregulated genes between DOX‐LIPUS and DOX‐Sham groups indicated that inhibition of neutrophil chemotaxis might be involved in the protective effects of LIPUS therapy. Flow cytometry analysis illustrated the inhibitory effects of LIPUS on DOX‐induced neutrophil recruitment and infiltration in the heart. Moreover, S100 calcium binding protein A8/A9 (S100a8/a9) was identified as a potential key target of LIPUS therapy. S100a8/a9 inhibition by ABR‐238901 showed a similar heart protective effect against DOX‐induced cardiomyopathy to LIPUS treatment. LIPUS therapy prevents DOX‐induced cardiotoxicity through inhibition of S100a8/a9‐mediated neutrophil recruitment to the heart, suggesting its potential application in cancer patients undergoing chemotherapy with DOX.
Catalytic Ozonation in Pulp and Paper Industry Wastewater Treatment: A Bibliometric Analysis
Authors: Athar Muhammad , Nawaz Muhammad , Nadeem Humayun , Rashid Muhammad Imran , Umer Asim , Iqbal Javed , Aadil Mahboob Ahmed 
Published: July 2023

AbstractThe pulp and paper industry is one of the most significant industrial water polluters, generating large volumes of wastewater with high levels of organic pollutants, suspended solids, and other contaminants. Catalytic ozonation has emerged as a promising technique for the treatment of pulp and paper industry wastewater. Numerous reviews have presented the research on catalytic ozonation; however, open literature is missing a bibliometric analysis. Therefore, this article presents a bibliometric analysis of the research available on catalytic ozonation in pulp and paper industry wastewater treatment. A total of 578 documents extracted from the Scopus database have been examined via VOSviewer, MS Excel, and Rstudio to identify the research trends, influential authors, and research institutions in the field. The results reveal that the number of publications on the topic has increased significantly in recent years. This study also identified several influential authors, institutions, and highlighted future research directions in the field. Overall, the study provides insights into the state of research on catalytic ozonation in pulp and paper industry wastewater treatment and could help guide future research efforts in this area.
Understanding the link between alcohol dependence and victimisation risk: Is risk explained by peers or alcohol behaviours?
Authors: Wojciechowski Thomas 
Published: July 2023

AbstractBackgroundAlcohol dependence is a risk factor for experiencing victimisation, but little is known about how peer and behavioural mechanisms may explain this relationship.AimsTo test deviant peer association and/or heavy‐episodic drinking frequency as mediators between alcohol dependence and risk for being victimised.MethodsThe Pathways to Desistance data were analysed. Generalised structural equation modelling was used to determine whether either or both of the hypothesised pathways significantly mediated the relationship between alcohol dependence and victimisation.ResultsAlcohol dependence at recruitment (age 14–17) was associated with higher odds of being a victim of some form of violence in Wave 3 (age x–y). This relationship was significantly mediated by deviant peer association but not heavy‐episodic drinking frequency between Waves 2 and 3.ConclusionsThese findings add knowledge about the mechanism of a link between early alcohol dependence and later violent victimisation among young offenders. They suggest that more focus on reducing delinquent peer association, or reducing its impact, is crucial to reducing further harms to these young people, in turn possibly affecting continuing substance use and reoffending risks. Peer mentoring programmes help to provide prosocial modelling and reduce deviant peer ties in some circumstances, and these findings suggest that the next step should be their evaluation specifically among justice‐involved young people with alcohol dependence. Providing additional funding and/or opportunities for involvement in such mentoring programmes may help to reduce the public health and financial costs associated with alcohol dependence in the juvenile justice system.
Papillary muscle rupture after transcatheter aortic valve implantation: A case report and literature review
Authors: Farouk Heba , Schöne Dominik , Witt Constantin , Bayyud Hamid , Kandil Mehmet , Kloppe Axel 
Published: July 2023

AbstractWe present a case of posterior papillary muscle rupture associated with severe eccentric mitral regurgitation following transcatheter aortic valve implantation, that was successfully treated with transcatheter edge to edge mitral repair and review similar cases in literature.
Development of EPAT: An assessment tool for pediatric hematology/oncology training programs
Authors: Moreira Daniel C. , Metzger Monika L. , Antillón‐Klussmann Federico , González‐Ramella Oscar , Gao Yijin , Bazzeh Faiha , Middlekauff Janet , Fox Irwin Leeanna , Gonzalez Miriam L. , Chantada Guillermo , Barr Ronald D. , Garrington Timothy , Hastings Caroline , Kutluk Tezer , Saab Raya , Khan Muhammad Saghir , Saha Vaskar , Rodríguez‐Galindo Carlos , Friedrich Paola 
Published: July 2023

AbstractPurposeIn the absence of a standardized tool to assess the quality of pediatric hematology/oncology training programs, the Education Program Assessment Tool (EPAT) was conceptualized as a user‐friendly and adaptable tool to evaluate and identify areas of opportunity, pinpoint needed modifications, and monitor progress for training programs around the world.MethodsThe development of EPAT consisted of three main phases: operationalization, consensus, and piloting. After each phase, the tool was iteratively modified based on feedback to improve its relevance, usability, and clarity.ResultsThe operationalization process led to the development of 10 domains with associated assessment questions. The two‐step consensus phase included an internal consensus phase to validate the domains and a subsequent external consensus phase to refine the domains and overall function of the tool. EPAT domains for programmatic evaluation are hospital infrastructure, patient care, education infrastructure, program basics, clinical exposure, theory, research, evaluation, educational culture, and graduate impact. EPAT was piloted in five training programs in five countries, representing diverse medical training and patient care contexts for proper validation of the tool. Face validity was confirmed by a correlation between the perceived and calculated scores for each domain (r = 0.78, p < .0001).ConclusionsEPAT was developed following a systematic approach, ultimately leading to a relevant tool to evaluate the different core elements of pediatric hematology/oncology training programs across the world. With EPAT, programs will have a tool to quantitatively evaluate their training, allowing for benchmarking with centers at the local, regional, and international level.
Conceptualizing the chromatic experience of environment: Two case studies using the Color Walk method
Authors: Pyykkö Saara 
Published: July 2023

AbstractDesigning the colors of a new neighborhood without a color definition of facades is challenging task. While there is a wealth of research on color perception and architectural color design, tools and methods are needed to understand the chromatic experience of areas. Thus, this case‐study research aims to explore the chromatic experience by introducing a new ethnographic Color Walk method. The participants are professionals in the fields of architecture and color. Two voice‐recorded and transcribed discussions are examined from two perspectives: the suitability of the Color Walk to conceptualize the chromatic experience of neighborhoods and analyzing the main concepts used by professional participants. The analysis shows that the seven main concepts are: (1) material; (2) light; (3) views in/from/into the area; (4) atmosphere; (5) identity; (6) landscape/nature/landscape architecture; and (7) architecture. Architecture includes four subareas: (a) the color scale of the building design, (b) the color scale of the urban design, (c) the history of architecture, and (d) color trends. The results indicate that the Color Walk method allows conceptualizing how environmental colors are experienced. However, several repetitions are needed to confirm all the concepts. Furthermore, complex facade colors are only one element of the chromatic experience. Thus, other aspects should also be emphasized in environmental color design. The results also show that environmental color design is related to urban design and building design. The findings of this study contribute to existing research by expanding the concepts of urban design to environmental color design.
Implementation of deep learning in liver pathology optimizes diagnosis of benign lesions and adenocarcinoma metastasis
Authors: Kriegsmann Mark , Kriegsmann Katharina , Steinbuss Georg , Zgorzelski Christiane , Albrecht Thomas , Heinrich Stefan , Farkas Stefan , Roth Wilfried , Dang Hien , Hausen Anne , Gaida Matthias M. 
Published: July 2023

AbstractIntroductionDifferentiation of histologically similar structures in the liver, including anatomical structures, benign bile duct lesions, or common types of liver metastases, can be challenging with conventional histological tissue sections alone. Accurate histopathological classification is paramount for the diagnosis and adequate treatment of the disease. Deep learning algorithms have been proposed for objective and consistent assessment of digital histopathological images.Materials and methodsIn the present study, we trained and evaluated deep learning algorithms based on the EfficientNetV2 and ResNetRS architectures to discriminate between different histopathological classes. For the required dataset, specialized surgical pathologists annotated seven different histological classes, including different non‐neoplastic anatomical structures, benign bile duct lesions, and liver metastases from colorectal and pancreatic adenocarcinoma in a large patient cohort. Annotation resulted in a total of 204.159 image patches, followed by discrimination analysis using our deep learning models. Model performance was evaluated on validation and test data using confusion matrices.ResultsEvaluation of the test set based on tiles and cases revealed overall highly satisfactory prediction capability of our algorithm for the different histological classes, resulting in a tile accuracy of 89% (38 413/43 059) and case accuracy of 94% (198/211). Importantly, the separation of metastasis versus benign lesions was certainly confident on case level, confirming the classification model performed with high diagnostic accuracy. Moreover, the whole curated raw data set is made publically available.ConclusionsDeep learning is a promising approach in surgical liver pathology supporting decision making in personalized medicine.