bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leaders' power construal influences malevolent creativity: The mediating role of organizational conspiracy beliefs
Authors: Fousiani Kyriaki , Xu Sylvia , van Prooijen Jan‐Willem 
Published: January 2025

AbstractHow employees perceive their leaders' power can influence their view and treatment of organizations. This study examines how employees' perceptions of their leaders' power construal—primarily as responsibility (PaR) or primarily as opportunity (PaO)—influence employee malevolent creativity towards the organization, with organizational conspiracy beliefs mediating this relationship. We hypothesized that when leaders' power is perceived primarily as responsibility, it diminishes employee endorsement of conspiracy beliefs and, in turn, reduces malevolent creativity. Conversely, perceiving leaders' power mainly as opportunity was expected to amplify conspiracy beliefs and subsequently malevolent creativity. Study 1, a three‐wave study among employees, showed that increased PaO was positively related to employee malevolent creativity through increased organizational conspiracy beliefs. Moreover, PaR was negatively related to malevolent creativity through organizational conspiracy beliefs. Study 2 (preregistered) experimentally tested these relationships and provided support for all hypotheses. Study 3 (also preregistered) manipulated exposure to organizational conspiracy theories (the mediator) to address the ‘measurement‐of‐mediation’ issue and found that conspiracy theories increase malevolent creativity. This study demonstrates the adverse consequences of leader's power construal as opportunity through employee's organizational conspiracy beliefs.
Outcome of Screening Questions for Temporomandibular Disorders and Related Treatment in Adult Patients Attending the Public Dental Service
Authors: Hjort Sofia , Hedenberg‐Magnusson Britt , Jasim Hajer 
Published: January 2025

ABSTRACTBackgroundApproximately 30% of the adult population experiences symptoms under the concept of temporomandibular disorder (TMD). To identify patients with TMD who may require further evaluation, three screening questions (3Q/TMD) have been introduced.ObjectivesThe aim of this study was to explore the prevalence of self‐reported TMD and the amount of treatment received by patients in the Public Dental Service in Stockholm and how many were referred to an orofacial pain specialist.MethodsHealth declarations from 402 012 patients 18 and older were included. Answers to the 3Q/TMD, gender, performed treatment, and referrals were extracted from the patients' records.ResultThe prevalence of affirmative answers to 3Q/TMD was 4.6% and higher in the 20–29 age group compared to the 60–69 group. Affirmative answers in general led to more treatment, and an affirmative answer to Q1 gave the highest probability of treatment (OR 5.13; 4.87, 5.41) with occlusal splint therapy being the most common. Age did not significantly predicting the amount of treatment (p = 0.05), although there was a tendency towards less treatment in older age groups. In total, 0.74% of the study population were referred to an orofacial pain specialist, with a higher probability of referral for those who answered affirmatively (p < 0.001).ConclusionThe prevalence of self‐reported TMD among patients in the Public Dental Service aligns with findings from similar studies. Patients who answered affirmatively to one or more of the screening questions were more likely to receive treatment or a referral. The 3Q/TMD effectively identifies patients who may benefit from further evaluation and referral, although the rate of treatment remains low.
Potential interaction between clorsulon and ivermectin for malaria vector control
Authors: Hongsuwong Thitipong , Khemrattrakool Pattarapon , Phanphoowong Theerawit , Sriwichai Patchara , Poovorawan Kittiyod , Tarning Joel , Kobylinski Kevin C. 
Published: January 2025

AbstractMass ivermectin (IVM) treatment of livestock (MITL) is under consideration as a malaria control tool as IVM‐treated livestock are lethal to blood‐feeding Anopheles mosquitoes. MITL is routinely used as a prophylaxis in livestock to reduce the burden and transmission of helminth infections. Recently, there has been a shift in the veterinary IVM market in Southeast Asia wherein nearly all standard IVM formulations are now co‐formulated with clorsulon (CLO). CLO is used to treat the trematode liver fluke, Fasciola hepatica. Thus, the co‐administration of IVM and CLO simultaneously targets multiple livestock infections. Additionally, F. hepatica frequently afflicts human populations in endemic areas, making control of F. hepatica in livestock beneficial for One Health. CLO interrupts glycolysis in F. hepatica, but its potential effect against Anopheles mosquitoes has never been evaluated. Anopheles dirus mosquitoes were blood‐fed CLO across a range of concentrations (1–10,000 nM; 0.38–3807 ng/mL), and mosquito survival was monitored for 10 days. Co‐feeding experiments were also performed with An. dirus blood‐fed on IVM at two concentrations (4 and 6 ng/mL) without and with CLO corresponding to peak concentration in cattle (Cmax) (2700 ng/mL) and five times the Cmax (13,500 ng/mL), and mosquito survival was monitored for 10 days. CLO had no mosquito‐lethal effect on An. dirus. The IVM and CLO co‐feed experiment did not indicate any altered effect of IVM on mosquito survival when co‐fed with CLO. IVM‐CLO livestock co‐formulations would not likely alter the Anopheles mosquito‐lethal effect of MITL. The use of MITL‐CLO for malaria control would have health benefits for livestock, treating helminth and liver fluke infections, and additional One Health benefits by reducing transmission risk of liver flukes to humans.
The comparison of spread of methylene blue after the Pericapsular Nerve Group block and a double injection selectively targeting the articular branches to the anterior hip capsule in human cadavers
Authors: Smits Rachel J. H. , Tan Edward C. T. H. , van den Bersselaar Luuk R. , de Bruijn Anne , Hendriksen Eva , Vissers Kris C. P. , Olde Dubbelink Kim T. E. , van der Wal Selina E. I. 
Published: January 2025

AbstractObjectivesIn this study, the spread of methylene blue was compared between an ultrasound‐guided Pericapsular Nerve Group (PENG) block and a double injection technique, where the approach towards the inferomedial acetabulum was added to the latter.MethodsThe two techniques were performed in 11 fresh frozen cadavers. The spread was measured after anatomical dissection in which the supplying femoral and obturator nerves were identified.Results and ConclusionOur study demonstrates adequate staining of the iliac bone with comparable distal and medial spread in both techniques, indicating that the PENG block with a single injection is adequate in blocking the hip capsule with 10 mL local anesthetics. Staining of the femoral nerve occurred in 2/6 specimens after the PENG block, and staining of the obturator nerve in 1 specimen in each group.
Enhancing Tolerance to Combined Heat and Drought Stress in Cool‐Season Grain Legumes: Mechanisms, Genetic Insights, and Future Directions
Authors: Priya Manu , Farooq Muhammad , Siddique Kadambot H. M. 
Published: January 2025

ABSTRACTThe increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L.), and common vetch (Vicia sativa L.). These legumes play a vital role in sustainable agricultural systems due to their nitrogen‐fixing ability and high nutritional value. This review synthesizes current knowledge of the impacts and tolerance mechanisms associated with combined heat and drought stresses in these crops. We evaluate physiological and biochemical responses to combined heat and drought stress, focusing on their detrimental effects on growth, development, and yield. Key genetic and molecular mechanisms, such as the roles of osmolytes, antioxidants, and stress‐responsive genes, are explored. We also discuss the intricate interplay between heat and drought stress signaling pathways, including the involvement of Ca2+ ions, reactive oxygen species, transcription factor DREB2A, and the endoplasmic reticulum in mediating stress responses. This comprehensive analysis offers new insights into developing resilient legume varieties to enhance agricultural sustainability under climate change. Future research should prioritize integrating omics technologies to unravel plant responses to combined abiotic stresses.
Functional characterisation of WRKY transcription factor CrWRKY48 involved in regulating seed abortion of Ponkan (Citrus reticulata)
Authors: Lu Liqing , Gao Xiong , Qi Yongjie , Zha Zixian , Gao Zhenghui , Ma Na , Wu Juxun , Yang Haijian , Yi Hualin 
Published: January 2025

AbstractCitrus fruits are one of the most important fruits in the world, and their seedless character is favored by consumers. WRKY is a plant‐specific transcription factor family involved in all aspects of plant growth and development. However, the molecular mechanism of seedless fruit formation in citrus and the role of the WRKY gene family in seed abortion are still poorly understood. In this study, we identified 47 WRKY family genes in the citrus fruit Citrus reticulata and comprehensively characterized the WRKY gene family through gene structure and evolutionary relationships. The expression patterns and protein interaction networks of the WRKY gene family were analyzed based on citrus seed abortion transcriptome data, and several WRKY genes that may be involved in the seed abortion regulation were excavated. Furthermore, CrWRKY48 was verified to regulate seed abortion positively in Arabidopsis thaliana, and the rate of seed abortion caused by overexpression of CrWRKY48 reached 45.48%. Using terminal deoxynucleotidyl transferase‐mediated dUTP nick‐end labelling assays, DNA affinity purification sequencing and yeast‐one‐hybrid assays, we found that CrWRKY48 activated excessive programmed cell death by regulating the expression of programmed cell death‐related genes such as SOBIR1. Our results show the potential regulation of the WRKY gene family for citrus seed abortion and provide novel insights into the role of CrWRKY48 in mediating citrus seed abortion by activating programmed cell death.
The spatiotemporal changes of metabolites in Pinellia ternata at different development stages by MALDI‐MSI
Authors: Pei Yifei , Feng Xue , Liu Ziyi , Chen Jialei , Wang Jialu , Zhang Xiangyu , Liu Haitao , Li Xiwen 
Published: January 2025

AbstractPinellia ternata is an herb species in the Pinellia genus with significant economic value due to its medicinal properties. Understanding the accumulation and spatial distribution characteristics of metabolites during the development of the medicinal part, the rhizome of P. ternata (PR), provides a basis for targeted metabolic regulation and quality evaluation. In this study, we used matrix‐assisted laser desorption/ionization mass spectrometry imaging (MALDI) and MS/MS to analyse metabolites at 5 representative stages (S1 to S5) of rhizome development in cross and longitudinal sections of the rhizome. A total of 168 metabolites were detected, with 13 being metabolites previously reported in PR. Additionally, Venn analysis revealed 12 bioactive differential metabolites during the growth process. Their spatial distribution and composition were analyzed, showing that alkaloids and amino acids were significantly distributed throughout the entire region and had higher relative contents compared to other metabolites. Flavonoids were more distributed in the outer regions of PR, potentially playing a greater role in combating biotic or abiotic stresses. Specifically, in cross‐sections, arginine, nicotinamide, and 2‐pentylpyridine showed a clear trend of accumulation from the outer to the inner from S1 to S5, while trigonelline, adenosine, cytidine, 3,4‐dihydroxycinnamyl alcohol, raffinose, choline alfoscerate, liquiritin, and apii exhibited the opposite trend. For longitudinal sections, trigonelline, 2‐pentylpyridine, choline alfoscerate and baicalein showed a trend of accumulation from the area of bud end to the far region during S1 to S5, while arginine showed opposite distribution trends. These findings deepen our understanding of the metabolic processes involved in the development of PR and have potential implications for variety improvement and quality control.
Insiders and Outsiders: The Role of Human Agents and Networks in System Change
Authors: Forsyth Miranda , Roberts Anthea 
Published: January 2025

ABSTRACTThis article focuses on the roles of insiders or outsiders in order to theorize the role that human agents play in systems change. It asks: (1) what strengths and weaknesses do insiders and outsiders have respectively as agents of change; and (2) what strategies are available to use these insights to increase, or to limit, the prospects of significant and lasting change? Drawing on an interdisciplinary range of scholarship, it develops a general theoretical framework for identifying the strengths and weaknesses of insiders and outsiders in terms of innovation (generating new ideas) and diffusion (promoting the adoption of new ideas). It identifies two strategies to leverage the strengths of both: (1) complexifying our understanding of change agents through identifying the special roles played by “insider–outsiders” and “outsider–insiders”; and (2) connecting insiders and outsiders through a process we refer to as “inside‐outside networked change.”
Efficacy of Supportive Care Interventions for Improving Posttraumatic Stress Symptoms and Resilience in Family Caregivers of Cancer‐Affected Children: A Meta‐Analysis of Randomized Controlled Trials
Authors: Yan Qianwen , Li Xia , Chen Yang , Li Linna , Hu Xiaolin 
Published: January 2025

ABSTRACTBackgroundThe diagnosis of pediatric cancer is a major shock to family caregivers, and posttraumatic stress symptoms (PTSSs) emerge as the most prevalent adverse psychological outcomes. However, not all family caregivers have sufficient resilience to cope with these challenges; thus, supportive care interventions are necessary. These interventions, which include psychosocial support, education, and other forms of assistance, are designed to enhance the well‐being of those affected by disease. In the past few years, more research has been delving into supportive care interventions for family caregivers of cancer‐affected children, yet there is still a variance in the results.ObjectiveTo investigate the impacts of supportive care interventions on PTSSs and resilience in family caregivers of cancer‐affected children, also focusing on the impacts of prerecruitment time to diagnosis, duration, type of intervention, and recruitment area on the outcomes.MethodsNine databases (Cochrane Library, Ovid MEDLINE, CINAHL Plus with Full Text, Embase, CNKI, Sinomed, WANFANG, VIP, and Web of Science) were searched from their inception to February 21, 2024. The revised Cochrane Risk of Bias tool and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method were used to evaluate the quality of evidence. To gauge the effectiveness of the interventions, we computed the standard mean difference (SMD) and the 95% confidence interval (CI) utilizing StataCorp (version 16.0). Sensitivity analysis and Egger's test were also conducted.ResultsSupportive care interventions significantly improved the PTSSs (SMD = −0.86, 95% CI [−1.39, −0.33], p < 0.01, I2 = 94.95%) and resilience (SMD = 0.85, 95% CI [0.26, 1.44], p < 0.01, I2 = 88.3%) among family caregivers of cancer‐affected children. Subgroup analyses revealed that early interventions for family caregivers after the diagnosis of children and the short‐term interventions were associated with improvements in their PTSS and resilience. Moreover, cognitive behavioral interventions were the most common type of interventions and were effective in supporting family caregivers. Additionally, supportive care interventions did not improve PTSSs among family caregivers in middle‐income countries.Linking Evidence to ActionSupportive care interventions have demonstrated efficacy in improving PTSSs and resilience among family caregivers of cancer‐affected children. This research proved the imperative of providing prompt supportive care to family caregivers early after the pediatric cancer diagnosis. Additionally, it is also necessary to further study and explore the optimal way to combine different intervention components based on caregivers' need and to develop regionally adapted and culturally sensitive supportive care interventions to better improve health outcomes for family caregivers.
Cable Force Distribution and Motion Control for a Cable-Driven Super-Redundant Robot Under Stiffness Constraints
Authors: Tuo Guiben , Wang Yongqing , Li Te , Shang Zhenye , Li Xu , Liu Haibo 
Published: January 2025

Abstract
Cable-driven super-redundant robots (CDSSR) with slender and flexible bodies have wide application potential in narrow spaces. However, the control accuracy of the robot is affected by the instability of the operating stiffness during motion, which is related to the diversity of the cable tension distribution solutions. To solve this problem, an analytical stiffness model of the cable-driven super-redundant robot is first constructed based on the virtual work principle. Then, an optimal cable tension distribution model based on energy optimization and stiffness constraint is proposed. Third, a motion control framework of cable-driven super-redundant robot with stiffness constraints is proposed. Finally, constant stiffness control experiments and repeated positioning accuracy experiments of robot end under different end stiffness conditions are carried out on a 21-DOF cable-driven super-redundant robot. The results show that the proposed control strategy can achieve constant stiffness control. When the stiffness of the robot is adjusted from 200 N/m to 300 N/m, the repeated positioning accuracy in the X, Y, and Z directions is increased by 40.00%, 27.62%, and 53.09%, respectively. When the end stiffness is adjusted from 300 N/m to 400 N/m, the repeated positioning accuracy in the X, Y, and Z directions is increased by 40.81%, 58.08%, and 64.99%, respectively. The experimental results show that the proposed cable force distribution model and control strategy are effective.
The Effects of Floor Isometric Trunk Extension Exercise on Muscle Thickness and Activation Vary Between Different Combinations of Duration and Repetition Number
Authors: Kellis Eleftherios , Konstantopoulos Athanasios , Ellinoudis Athanasios 
Published: January 2025

Context: Intermittent floor trunk extensions are popular exercises in group fitness programs. The aim of this study was to investigate whether fewer repetitions of longer isometric trunk extension efforts compared with more repetitions of shorter isometric contractions have different acute effects on muscle thickness and activation as well as perceived exertion. Design: This study followed a cross-sectional design. Methods: Twenty healthy young males performed floor prone trunk extension exercises using 3 different exercise protocols of repetition and duration: 10 × 5 seconds (D10 × 5), 2 × 25 seconds (D2 × 25), and 5 × 10 seconds (D5 × 10). Ultrasound multifidus thickness and rate of perceived exertion on a 10-point scale were measured immediately after each protocol. Electromyographic activation from the erector spinae, multifidus, and gluteus maximum during each protocol was measured using bipolar surface electrodes. Results: The longer duration (D2 × 25) protocol showed a significant greater rate of perceived exertion (6.22 [0.73]) and rest multifidus thickness change (median: 8.04%) compared with the other protocols (P < .05). Within each protocol, root mean square of all muscles increased from trial to trial in the D2 × 25 and D5 × 10 (P < .05), but not during the D10 × 5 protocol (P > .05). The maximum root mean square was achieved in the shorter duration (D10 × 5) protocol compared with the other ones (P < .05). Conclusion: If trunk extension exercises on the floor are used in a training setting, then using exercises with long duration and fewer repetitions may elicit a greater metabolic response.
‘Fighting every day’: exploring caregiver quality of life and perspectives on healthcare services for children with dementia – a cross-sectional, mixed-methods study
Authors: Djafar Jason , Nevin Suzanne , Smith Nicholas , Ardern-Holmes Simone , Bhattacharya Kaustuv , Dale Russell , Ellaway Carolyn , Grattan Sarah , Johnson Alexandra , Kandula Tejaswi , Kariyawasam Didu S , Lewis Katherine , Meagher Christian Elias , Mohammad Shekeeb , Farrar Michelle Anne 
Published: January 2025

ObjectiveTo explore quality of life outcomes for caregivers of children with childhood dementia including the positive and negative impact of caregiving. The secondary aim was to explore caregivers’ perspectives on healthcare services for children with dementia.DesignCross-sectional, mixed-methods study with analyses of quantitative and qualitative data collected via online survey.SettingAustralian tertiary referral children’s hospitals, clinics and community advocacy groups.Patients40 caregivers of children with dementia.InterventionsThe survey was developed by a multidisciplinary team of clinicians including paediatric neurologists and behavioural scientists with experience in caring for families with childhood dementias and mixed-methods research.Main outcome measuresSurveys assessed caregiver-reported health-related quality of life, psychological distress, the impacts of caregiving and perspectives on healthcare services and how they may be improved for children with dementia.ResultsPsychological distress was reported by 72.5%, caregiver stress by 67%, chronic pain or discomfort by 43% and for 87.5% their child’s condition had a moderate or severe impact on their ability to do regular daily activities. Caregivers voiced a desire for more integrated care, increased general awareness and education around childhood dementia and a greater need for more trained support services.ConclusionsCaregivers of children with dementia experience high levels of psychological distress, physical and social consequences. This study highlights the need for integrated care and psychosocial support to efficiently connect children and families with appropriate healthcare services and resources.
Giant sigmoid diverticulum
Authors: Ong Ming San Elaine , Ali Mafas , Sprakes Michael Bramwell , Burr Nicholas Ewin 
Published: January 2025

Giant colonic diverticulum is an uncommon presentation of colonic diverticular disease. It is characterised by the presence of a diverticulum exceeding 4 cm in size, with approximately 90% of the cases involving the sigmoid colon. Typically, diagnosis relies on CT of the abdomen and pelvis (CTAP). The preferred treatment approach is sigmoid resection with a primary colonic anastomosis. However, in complicated or emergency cases, proctosigmoidectomy with end colostomy (Hartmann’s procedure) is often considered the safest surgical option.We present an atypical case of a symptomatic patient with a giant sigmoid diverticulum that had increased in size and symptoms over several years. Initial diagnosis by CTAP revealed an incidental 6 cm sigmoid diverticulum. Over approximately 6 years, the diverticulum enlarged substantially, reaching 20 cm in size. This caused compression of the stomach and splinting of the left hemidiaphragm, resulting in nutritional failure. He was admitted with a plan to optimise for curative surgery; however complications such as nutritional failure and frailty developed, leading to a decision for palliative care.