bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benthic Invertebrates on the Move: A Tale of Ocean Warming and Sediment Carbon Storage
Authors: Bianchi Thomas S. , Brown Craig J. , Snelgrove Paul V. R. , Stanley Ryan R. E. , Cote David , Morris Corey 
Published: January 2023

AbstractOngoing effects of climate change create a dual challenge of shifting distributions of organisms and concerns about the fate of organic carbon in nature. Marine sediments store vast amounts of organic carbon, but the fate of that material hinges on the biology of organisms associated with the seafloor and how they influence rates of carbon decomposition and burial. Shifts in large megafauna that disturb and thus help to oxygenate sediments could have important ramifications regarding whether sediments release or store carbon for long periods of time. We consider snow crab and lobster, two commercially important seafloor species in the Northeastern Atlantic, and the potential effects of ongoing changes in their distributions and that of their fisheries for future climate scenarios. These ongoing biogeographic shifts, considered in tandem with areas of seabed legislatively protected from fishing impacts and thus not confounded by cumulative effects of fishing gear disturbance, offer an opportunity to study how newly arrived species that disturb large areas of the seafloor might influence the global carbon cycle.
A flexible block classical Gram–Schmidt skeleton with reorthogonalization
Authors: Zou Qinmeng 
Published: January 2023

AbstractWe investigate a variant of the reorthogonalized block classical Gram–Schmidt method for computing the QR factorization of a full column rank matrix. Our aim is to bound the loss of orthogonality even when the first local QR algorithm is only conditionally stable. In particular, this allows the use of modified Gram–Schmidt instead of Householder transformations as the first local QR algorithm. Numerical experiments confirm the stable behavior of the new variant. We also examine the use of non‐QR local factorization and show by example that the resulting variants, although less stable, may also be applied to ill‐conditioned problems.
The equivocal image of young social enterprises—How self‐ versus other‐oriented values influence external perceptions
Authors: Yahyaoui Yasmine , Jakob Eva A. , Steinmetz Holger , Wehner Marius C. , Isidor Rodrigo , Kabst Rüdiger 
Published: January 2023

AbstractSocial enterprises follow the dual mission of achieving social aims as well as attaining financial sustainability and therefore elude easy categorization into either a non‐profit or for‐profit organization. Consequently, social enterprises might struggle with their image since external stakeholders (e.g., job applicants and customers) could hold back their support when the enterprise's dual aims seem unusual to them. Despite the importance of the image to gain stakeholder support, factors that determine how individuals perceive social enterprises are underexplored, especially in their early life stages before they have developed reputational capital and brand recognition. Following human value theory, we propose that stakeholders' self‐transcendence (“other‐oriented”) versus self‐enhancement (“self‐centered”) values explain how they evaluate social versus commercial enterprises. In a vignette study with 945 individuals, we reveal that social enterprises are more likely to attract self‐transcendent individuals whereas individuals with stronger self‐enhancement values are less likely to feel attracted to social enterprises. Moreover, our findings show that individuals' values were more strongly related to the image of social enterprises than to the image of commercial enterprises. Thus, external individuals' values lead to stronger and more contrasting reactions regarding social compared to commercial enterprises. The findings indicate that the image of social enterprises is more equivocal and distinct compared to commercial enterprises and therefore might require a different theoretical understanding and careful management as it depends on stakeholders' deep‐seated values.
Understanding China's political will for sustainability and conservation gains
Authors: Cheung Hubert , Feng Yutong Phoenix , Hinsley Amy , Lee Tien Ming , Possingham Hugh P. , Smith Stephen N. , Thomas‐Walters Laura , Wang Yifu , Biggs Duan 
Published: January 2023

AbstractPolitical will is a critical determinant of the success or failure of environmental policies and interventions. Harnessing the political will necessary to implement environmental solutions can be challenging because environmental priorities may compete with other societal interests in policymaking.Environmental solutions are more politically feasible if fundamentally aligned with the core interests of key policymakers. Understanding the political agendas of decision‐makers enables conservationists to identify where political will already exists, and allows environmental objectives to piggyback on the motivation to deliver results.In this paper, we explore the core interests of the Chinese leadership to uncover opportunities to leverage Beijing's political will for sustainability and conservation gains. China's growing influence on ecosystems and natural resource use both within and beyond its borders makes an analysis of its leadership's political will valuable and timely.Read the freePlain Language Summaryfor this article on the Journal blog.
Feasibility, acceptability, and preliminary findings of a school‐based intervention for recently arrived immigrant middle‐school students
Authors: Ma Pei‐Wen W. , Torres Aileen , Akoto Marsha A. 
Published: January 2023

AbstractThe Cultural Adjustment Group is a pilot school‐based group intervention for recently arrived immigrant middle school students. This study examined the feasibility, acceptability, and provided preliminary assessment data to guide future intervention research. Seventy (Male, n = 43; Female, n = 27) immigrant students who were Spanish‐speaking, Arabic‐speaking, and Bangla‐speaking (ages 10–16, M = 13.17) from an urban school district in the Northeastern United States participated in this intervention. Pre and postgroup surveys and exit‐group interviews were conducted to evaluate the program. The findings demonstrated this intervention has good feasibility and high acceptability by the participants. The Bangla‐speaking group reported higher levels of clinical symptoms and perceived discrimination at pretest and reported a clinically significant reduction in clinical symptoms and acculturative stress at posttest. There were no clinically significant changes in the other two groups. The results offer guidance for future implementation of school‐based intervention for newcomer students.
CO2‐based amphiphilic block copolymers: Facile one‐step synthesis and aqueous self‐assembly
Authors: Qu Rui , Wei Zhenyu , Suo Hongyi , Gu Yanan , Wang Xue , Xin Zhirong , Qin Yusheng 
Published: January 2023

AbstractConstruction of CO2‐based amphiphilic block copolymers (ABCs) is an efficient method for providing CO2‐based polycarbonates with self‐assembly properties in aqueous media. It is challenging to construct CO2‐based ABCs by one‐step strategies from mixed monomers because hydrophilic blocks, usually composed of polar monomers, have negative effects on the synthesis of polycarbonates. In this work, we report a one‐step method to construct CO2‐based ABCs obtained by simultaneous ring‐opening copolymerization (ROCOP) of CO2/epoxides and reversible addition‐fragmentation chain transfer (RAFT) polymerization of N‐isopropyl acrylamide (NIPAM). A trithiocarbonate/carboxy compound was used as the bifunctional chain transfer agent, and an aluminum porphyrin complex was used as the catalyst for ROCOP, which proved to be efficient in CO2 copolymerization even in the presence of NIPAM with strong polarity. This strategy allows flexible control over the molecular weight (5–16 kg/mol) and the hydrophilic‐hydrophobic balance (HLB 9–18) of the ABCs, and ensures narrow polydispersity Đ (1.1–1.3) of the polymers. The ABCs can further self‐assemble into micelles in water with controllable diameters and reversible phase transformation behavior with temperature changes from 25 to 40 °C. This simple route to CO2‐based ABCs with multiple functions has large potential in biomedical applications.
Docetaxel versus abiraterone for metastatic hormone‐sensitive prostate cancer with focus on efficacy of sequential therapy
Authors: Yanagisawa Takafumi , Hata Kenichi , Narita Shintaro , Hatakeyama Shingo , Mori Keiichiro , Yata Yuji , Sano Takayuki , Otsuka Takashi , Hara Shuhei , Miyajima Keiichiro , Enei Yuki , Fukuokaya Wataru , Nakazono Minoru , Matsukawa Akihiro , Miki Jun , Habuchi Tomonori , Ohyama Chikara , Shariat Shahrokh F. , Kimura Takahiro 
Published: January 2023

AbstractPurposeWe aimed to assess the oncologic efficacy of combining docetaxel (DOC) versus abiraterone (ABI) with androgen deprivation therapy (ADT) in patients with high‐risk metastatic hormone‐sensitive prostate cancer (mHSPC), with a focus on the efficacy of sequential therapy, in a real‐world clinical practice setting.MethodsThe records of 336 patients who harbored de novo high‐risk mHSPC, based on the LATITUDE criteria, and had received ADT with either DOC (n = 109) or ABI (n = 227) were retrospectively analyzed. Overall survival (OS), cancer‐specific survival (CSS), progression‐free survival (PFS), including time to castration‐resistant prostate cancer (CRPC), time to 2nd‐line progression (PFS2), and 2nd‐ and 3rd‐line PFS, were compared. We used one‐to‐two propensity score matching to minimize the confounders. The differential efficacy of 2nd‐line therapy based on agents in each arm was evaluated using the unmatched cohort as an additional interest.ResultsAfter propensity score matching, 86 patients treated with DOC + ADT and 172 with ABI + ADT were available for analyses. The 3‐year OS and CSS for DOC versus ABI were 76.2% versus 75.1% (p = 0.8) and 78.2% versus 78.6% (p = 1), respectively. There was no difference in the median PFS2 (49 vs. 43 months, p = 0.39), while the median time to CRPC in patients treated with ABI was significantly longer compared to those treated with DOC (42 vs. 22 months; p = 0.006). The median 2nd‐line PFS (14 vs. 4 months, p < 0.001) and 3rd‐line PFS (4 vs. 2 months, p = 0.012) were significantly better in the DOC group than in the ABI group. Among the unmatched cohort, after ABI for mHSPC, the median 2nd‐line PFS did not differ between the patients treated with DOC and those treated with enzalutamide as 2nd‐line therapy (both 3 months, p = 0.8).ConclusionsADT with DOC or ABI has comparable oncologic outcomes in terms of OS, CSS, and PFS2 in patients with de novo high‐risk mHSPC. Compared to DOC, ABI resulted in longer time to CRPC but worse 2nd and 3rd‐line PFS. Further studies are needed to clarify the optimal sequence of therapy in the upfront intensive treatment era.
Design, synthesis, and fungicidal activities of novel piperazine thiazole derivatives containing oxime ether or oxime ester moieties
Authors: Peng Xing‐Jie , Tian Xue‐Rong , Yu Shu‐Jing , Zhao Tong‐Tong , Bian Qiang , Zhao Wei‐Guang 
Published: January 2023

AbstractBACKGROUNDTo study the effect of changing the piperidine ring of oxathiapiprolin on the fungicidal activity, we designed and synthesized novel piperazine thiazole derivatives containing oxime ether or oxime ester moieties, and studied their fungicidal activities against Phytophthora capsici in vitro.RESULTSThese derivatives showed moderate to good fungicidal activities against Phytophthora capsici, two oxime ether derivatives showed higher fungicidal activity in vitro than dimethomorph (EC50 = 0.1331 μg mL−1) and comparable to oxathiapiprolin (EC50 = 0.0042 μg mL−1). Oxime ester derivatives showed significantly reduced activities compared with oxime ether derivatives. Most of these derivatives showed broad‐spectrum fungicidal activity against the other eight kinds of fungi. Moreover, four derivatives exhibited good antifungal activities in vivo against Phytophthora capsici, Pseudoperonospora cubensis, and Phytophthora infestans. The hyphae morphology study showed that compound 10d might cause mycelial abnormalities of Phytophthora capsici.CONCLUSIONThe activity of 10b against Phytophthora infestans was better than that of mandipropamid, and compound 10d exhibited higher fungicidal activities against Pseudoperonospora cubensis and Phytophthora infestans than mandipropamid. These two derivatives emerged as promising candidates for antifungal drugs. © 2023 Society of Chemical Industry.
Dengue fever ophthalmic manifestations: A review and update
Authors: Lucena‐Neto Francisco Dias , Falcão Luiz Fabio Magno , Moraes Evelly Christinne da Silva , David Joacy Pedro Franco , Vieira‐Junior Adolfo de Souza , Silva Camilla Costa , de Sousa Jorge Rodrigues , Duarte Maria Irma Seixas , Vasconcelos Pedro Fernando da Costa , Quaresma Juarez Antônio Simões 
Published: January 2023

AbstractDengue fever, the most common arbovirus disease, affects an estimated 390 million people annually. Dengue virus (DENV) is an RNA virus of the Flaviviridae family with four different serotypes. Dengue haemorrhagic fever is the deadliest form of dengue infection and is characterised by thrombocytopaenia, hypotension, and the possibility of multi‐system organ failure. The mechanism hypothesised for DENV viral replication is intrinsic antibody‐dependent enhancement, which refers to Fcγ receptor‐mediated viral amplification. This hypothesis suggests that the internalisation of DENV through the Fcγ receptor inhibits antiviral genes by suppressing type‐1 interferon‐mediated antiviral responses. DENV NS1 antibodies can promote the release of various inflammatory mediators in the nuclear transcription factor pathway (NF‐κB‐dependent), including monocyte chemoattractant protein (MCP)‐1, interleukin (IL)‐6, and IL‐8. As a result, MCP‐1 increases ICAM‐1 expression and facilitates leukocyte transmigration. In addition, anti‐DENV NS1 antibodies induce endothelial cell apoptosis via a nitric oxide‐regulated pathway. A chain reaction involving pre‐existing DENV heterotypic antibodies and innate immune cells causes dysfunction in complement system activity and contributes to the action of autoantibodies and anti‐endothelial cells, resulting in endothelial cell dysfunction, blood‐retinal barrier breakdown, haemorrhage, and plasma leakage. A spectrum of ocular diseases associated with DENV infection, ranging from haemorrhagic to inflammatory manifestations, has been reported in the literature. Although rare, ophthalmic manifestations can occur in both the anterior and posterior segments and are usually associated with thrombocytopenia. The most common ocular complication is haemorrhage. However, ophthalmic complications, such as anterior uveitis and vasculitis, suggest an immune‐mediated pathogenesis.
Research Process on Photodetectors based on Group‐10 Transition Metal Dichalcogenides
Authors: Ahmad Waqas , Wu Jiang , Zhuang Qiandong , Neogi Arup , Wang Zhiming 
Published: January 2023

AbstractRapidly evolving group‐10 transition metal dichalcogenides (TMDCs) offer remarkable electronic, optical, and mechanical properties, making them promising candidates for advanced optoelectronic applications. Compared to most TMDCs semiconductors, group‐10‐TMDCs possess unique structures, narrow bandgap, and influential physical properties that motivate the development of broadband photodetectors, specifically infrared photodetectors. This review presents the latest developments in the fabrication of broadband photodetectors based on conventional 2D TMDCs. It mainly focuses on the recent developments in group‐10 TMDCs from the perspective of the lattice structure and synthesis techniques. Recent progress in group‐10 TMDCs and their heterostructures with different dimensionality of materials‐based broadband photodetectors is provided. Moreover, this review accounts for the latest applications of group‐10 TMDCs in the fields of nanoelectronics and optoelectronics. Finally, conclusions and outlooks are summarized to provide perspectives for next‐generation broadband photodetectors based on group‐10 TMDCs.
Bis(pentafluorophenyl)borane Induced Tandem Hydroboration‐Carboboration of Cyclooctatetraene
Authors: Müller Tizian , Hasenbeck Max , Becker Jonathan , Gellrich Urs 
Published: January 2023

AbstractWe report here the formation of the bridged boracycle 1 upon reaction of cyclooctatetraene with bis(pentafluorophenyl)borane. Computations indicate that the reaction commences with a hydroboration and that the high Lewis acidity of the bis(pentafluorophenyl)borane then induces a rearrangement with cleavage of a carbon–carbon bond via a nonclassical zwitterion and a final 1,1‐carboboration. An intermediate of the reaction was captured as tri‐tert‐butylphosphine adduct.
Generalized volume-complexity for two-sided hyperscaling violating black branes
Authors: Omidi Farzad 
Published: January 2023

Abstract
In this paper, we investigate generalized volume-complexity $$ \mathcal{C} $$
C
gen for a two-sided uncharged HV black brane in d + 2 dimensions. This quantity which was recently introduced in [48], is an extension of volume in the Complexity=Volume (CV) proposal, by adding higher curvature corrections with a coupling constant λ to the volume functional. We numerically calculate the growth rate of $$ \mathcal{C} $$
C
gen for different values of the hyperscaling violation exponent θ and dynamical exponent z. It is observed that $$ \mathcal{C} $$
C
gen always grows linearly at late times provided that we choose λ properly. Moreover, it approaches its late time value from below. For the case λ = 0, we find an analytic expression for the late time growth rate for arbitrary values of θ and z. However, for λ ≠ 0, the late time growth rate can only be calculated analytically for some specific values of θ and z. We also examine the dependence of the growth rate on d, θ, z and λ. Furthermore, we calculate the complexity of formation obtained from volume-complexity and show that it is not UV divergent. We also examine its dependence on the thermal entropy and temperature of the black brane. At the end, we also numerically calculate the growth rate of $$ \mathcal{C} $$
C
gen for the case where the higher curvature corrections are a linear combination of the Ricci scalar, square of the Ricci tensor and square of the Riemann tensor. We show that for appropriate values of the coupling constants, the late time growth rate is again linear.
Compact Minimal Submanifolds in a Large Class of Riemannian Manifolds
Authors: Herrera J. , Rubio R. M. , Salamanca J. J. 
Published: January 2023

AbstractThrough a new technique, we provide uniqueness, rigidity and non-existence results for compact minimal submanifolds of arbitrary dimension in a large class of Riemannian manifolds, which include between others, Riemannian double-twisted and warped products. Moreover, we show that our results can be applied in particular, to space forms and Cartan–Hadamard manifolds, re-obtaining several classic results in a different approach. Interesting applications to Geometric Analysis are also showed.
Bottom-up proteomics analysis for adduction of the broad-spectrum herbicide atrazine to histone
Authors: Chu Shaogang , Letcher Robert J. 
Published: January 2023

AbstractHistones are the major proteinaceous components of chromatin in eukaryotic cells and an important part of the epigenome. The broad-spectrum herbicide atrazine (2-chloro-4-[ethylamino]-6-[isopropylamino]-1, 3, 5-triazine) and its metabolites are known to form protein adducts, but the formation of atrazine–histone adducts has not been studied. In this study, a bottom-up proteomics analysis method was optimized and applied to identify histone adduction by atrazine in vitro. Whole histones of calf thymus or human histone H3.3 were incubated with atrazine. After solvent-based protein precipitation, the protein was digested by trypsin/Glu-C and the resulting peptides were analyzed by high-resolution mass spectrometry using an ultra-high-performance liquid chromatograph interfaced with a quadrupole Exactive-Orbitrap mass spectrometer. The resulting tryptic/Glu-C peptide of DTNLCAIHAK from calf thymus histone H3.1 or human histone H3.3 was identified with an accurate mass shift of  +179.117 Da in atrazine incubated samples. It is deduced that a chemical group with an elemental composition of C8H13N5 (179.1171 Da) from atrazine adducted with calf thymus histone H3.1 or human histone H3.3. It was confirmed by MS/MS analysis that the adduction position was at its cysteine 110 residue. Time- and concentration-dependent assays also confirmed the non-enzymatic covalent modification of histone H3.3 by atrazine in vitro. Thus, the potential exists that atrazine adduction may lead to the alteration of histones that subsequently disturbs their normal function.
Graphical abstract
Failure induces task-irrelevant exploration during a stencil task
Authors: van der Kooij Katinka , van Mastrigt Nina M. , Cashaback Joshua G. A. 
Published: January 2023

AbstractDuring reward-based motor tasks, performance failure leads to an increase in movement variability along task-relevant dimensions. These increases in movement variability are indicative of exploratory behaviour in search of a better, more successful motor action. It is unclear whether failure also induces exploration along task-irrelevant dimensions that do not influence performance. In this study, we ask whether participants would explore the task-irrelevant dimension while they performed a stencil task. With a stylus, participants applied downward, normal force that influenced whether they received reward (task-relevant) as they simultaneously made erasing-like movement patterns along the tablet that did not influence performance (task-irrelevant). In this task, the movement pattern was analyzed as the distribution of movement directions within a movement. The results showed significant exploration of task-relevant force and task-irrelevant movement patterns. We conclude that failure can induce additional movement variability along a task-irrelevant dimension.
Comparison of the effect of DLI according to cell sources in relapsed AML after allogeneic stem cell transplantation
Authors: Park Woochan , Byun Ja Min , Hong Junshik , Kim Inho , Shin Dong-Yeop , Park Seonyang , Koh Youngil , Yoon Sung-Soo 
Published: January 2023

AbstractFor relapsed acute myeloid leukemia (AML) patients who received allogeneic hematopoietic stem cell transplantation, donor lymphocyte infusion (DLI) is an effective therapy. However, the cell source of DLI remains a topic of debate. In this study, we aimed to compare the efficacy and safety of G-CSF mobilized cells (G-DLI) with conventionally collected DLI (C-DLI). A total of 81 patients (50 C-DLI vs. 31 G-DLI) were assessed for clinical outcomes. There were no statistically significant differences in the baseline characteristics between the two groups including AML risk, donor types, interval from relapse to DLI, and infused CD3+ cell count. Although not statistically significant, complete remission (CR) and chimerism conversion rates were higher in G-DLI than in C-DLI: 51.6% vs. 28.0%, P = 0.057 and 42.3% vs. 28.2%, P = 0.363, respectively. There was no difference in acute graft-versus-host disease (GVHD) incidence and severity of acute GVHD between the two groups. The median overall survival (OS) of the G-DLI and C-DLI groups was 139 days and 106 days, respectively (P = 0.58). In conclusion, G-DLI appears to be a safe and an equally efficacious substitute for C-DLI, which is more readily available.