bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Evaluation of Green Growth in Selected OECD Countries
Authors: Kasztelan Armand 
Published: January 2023

Green growth is a relatively new concept, which has appeared in the international discussion in response to the increasing environmental threats and also as a potentially effective means to deal with the outcomes of the financial crisis of 2008. According to the OECD (2011a), green growth means taking measures conducive to growth and economic development, while ensuring that natural assets continue to provide the resources and environmental services that contribute to the countryâ€™s prosperity. The purpose of this article is to analyze the level of green growth in selected OECD countries. Research was carried out based on Hellwigâ€™s method, which enabled the construction of a synthetic measure of â€œgreeningâ€ of the growth. The adopted method made it possible to evaluate the studied phenomenon as a whole, providing grounds for assigning the selected countries into four groups, characterized by similar levels of green growth. In Group I, showing the highest level, there is only one countryâ€”Denmark. Conversely, 12 of the 21 countries analyzed were assigned to Group IVÂ Keywords: green growth; sustainable development; environmental protection; OECD; taxonomic methods; Hellwigâ€™s method;
Canopy management through crop forcing impacts grapevine cv. ‘Touriga Nacional’ performance, ripening and berry metabolomics profile
Authors: L. Cabral Inês , Teixeira António , Ferrier Manon , Lanoue Arnaud , Valente Joana , Rogerson Frank S. , Alves Fernando , M. P. Carvalho Susana , Gerós Hernâni Varanda , Queiroz Jorge 
Published: January 2023

Climate changes are speeding up the maturation of grapes in numerous areas of the world, including in the Mediterranean basin, but warmer temperatures often uncouple technical and phenolic maturity, resulting in unbalanced wines. We tested the efficacy of crop forcing (CF) in delaying the maturation of cv. ‘Touriga Nacional’ vines of the Douro Region, and their impacts on plant performance, berry quality attributes and metabolome were also evaluated. In two consecutive seasons (2019 and 2020), CF was conducted 15 (CF1) and 30 (CF2) days after fruit set by hedging growing shoots to five nodes and removing summer laterals, leaves and clusters. Results showed that while CF2 delayed ripening up to 51 days till first autumn rainfall, which compromised optimal sugar ripeness, CF1 delayed the technical maturation by one month, but both treatments severely impacted the production, mainly CF1, which reduced grapevine yield up to 90 %. The effect of CF in protecting vines against drought stress was not evident, judging by the values of leaf pre-dawn water potential measured along both seasons. CF1 and CF2 resulted in berries with lower pH and higher titratable acidity than controls, while total phenolics content increased by up to 48 % in 2020. A UPLC–MS-based targeted metabolomic analysis showed that CF increased the relative abundance of key metabolites like flavan-3-ols (i.e., catechin gallate increased by up to 661 %), trihydroxylated anthocyanins (i.e., delphinidin-3-O-glucoside increased by up to 656 % after CF2) and stilbenes (resveratrol increased by up to 700 % after CF2) with potential positive impacts in wine quality.
SYSTEM ANALYSIS OF THE SULFATION PROCESS IN THE PRODUCTION OF SURFACTANT SUBSTANCES
Authors: Dzevochko O. , Podustov M. , Dzevochko A. 
Published: January 2023

Data on the use of surface-active substances in various areas of Ukrainian industry are given. The rapid development of the production of surface-active substances is shown. The main stages of the production of surface-active substances are given. It is shown that the sulfation stage is the main one, at which high quality indicators of the obtained products are achieved.
The main disadvantages and advantages of sulfating agents in the technology of surface-active substances (surfactants) are given. The characteristics of the equipment and technological schemes of the sulfation process of organic substances are given.
It is claimed that the use of tubular film absorbers with a downward flow of phases is currently the most promising for use in industrial conditions.
Convective diffusion equations for the simplified models of Lewis – Whitman, Levich, Higby, Dankverts are given.
It is proposed to present the process of sulfation in a tubular film absorber with the following stages: the process of mass transfer of gaseous sulfur trioxide to the surface of the interface, the process of absorption of sulfur trioxide by an organic substance with the passage of an exothermic chemical reaction, the process of heat exchange between the liquid phase and the gaseous air flow, the process of heat exchange between the liquid phase and the flow of cooling water. The equation for calculating the mass transfer coefficient is given, which allows obtaining data close to Gutierrez's experimental data. The passage of successive chemical reactions during the absorption of sulfur trioxide by organic raw materials is shown. Kinetic equations and methods of calculating the degree of sulfation and color of the obtained products are given. Basic equations for calculating heat transfer coefficients and heat transfer coefficients are given.
The results of mathematical modeling of the sulfation process in a tubular film absorber are given.
The possibility of achieving high quality indicators of the obtained product is shown: the degree of sulfation is 97,9 %, the color is 1 unit on the iodine scale.
Olecranon Fractures
Authors: Hamoodi Zaid , Duckworth Andrew D. , Watts Adam C. 
Published: January 2023

» Olecranon fractures account for 10% of all elbow fractures and are more likely to result from a low-energy injury. A displaced fracture with a stable ulnohumeral joint (Mayo type 2) is the most common type of injury.» The management of an isolated olecranon fracture is based on patient factors (age, functional demand, and if medically fit to undergo surgery) and fracture characteristics including displacement, fragmentation, and elbow stability.» Nonoperative management can be successfully used in undisplaced fractures (Mayo type 1) and in displaced fractures (Mayo type 2) in frail patients with lower functional demands.» Patients with displaced olecranon fractures with a stable ulnohumeral joint without significant articular surface fragmentation (Mayo type 2A) can be managed with tension band wiring, plate osteosynthesis (PO), intramedullary fixation, or suture repair.» PO is advocated for multifragmentary fractures and fractures that are associated with ulnohumeral instability. It is essential to consider the variable anatomy of the proximal ulna during surgery.
Hybrid Deterministic-Stochastic Rainfall-Flow Model for Projecting Seasonal and Annual Flows in Sub-Basins of the State of Paraná
Authors: Magerski Juliane Macedo , Filho Jorim Sousa das Virgens 
Published: January 2023

Abstract
Estimating and simulating hydroclimatological variables is important for regional water management, since it has the purpose of mitigating socioeconomic and environmental effects. In this context, rainfall-flow models based on seasonal and annual periods can be an important tool for management of regional water resources. The objective of this work was to develop a hybrid deterministic-stochastic rainfall-flow model based on historical hydroclimatological records of the Lower Ivai River and Upper Tibagi River sub-basins, in the state of Paraná, Brazil. Monthly fluviometric and pluviometric data of 10 locations were obtained from the Paraná Waters Institute, and converted into seasonal and annual periods. The concept of equivalent flow was applied to develop a regressive model between the observed and estimated accumulated flows. The results were evaluated by the Shapiro-Wilk (S-W), Komogorov-Smirnov (K-S), Wilcoxon (WCX), and Brown-Forsythe (B-F) tests at 5% level. Significant differences in homogeneity were found for the estimated data series; thus, statistical procedures were carried out for correcting bias through stochastic simulation. The S-W, K-S, WCX, and B-F tests were carried out again, indicating very good results, as the observed and projected flow distributions, means, and variances were very similar. In addition, a graphical analysis showed that the data of observed and projected flows presented the same trend. Thus, the rainfall-flow model proposed showed a simple applicability, presenting no deformities due to local factors, as the sub-basins are in different climatic regions.
Associations Between the Retinal/Choroidal Microvasculature and Carotid Plaque in Patients with CHD: An Optical Coherence Tomography Angiography Study
Authors: Wang Zhiliang , jiang jing , Wang Jin , Wang Yucen , Wang Luoziyi , Qian Yiwen 
Published: January 2023

AbstractBackgroundTo investigate the associations between retinal/choroidal microvasculature and carotid plaque in patients with CHD assessed by optical coherence tomography angiography (OCTA).MethodsThis study included 127 CHD patients with and 79 without carotid plaque. Each patient had both OCTA taken and digitized to determine retinal/choroidal thickness, vessel density and flow area and carotid ultrasound for carotid plaque size and stability measurement. SCP, DCP, out retina and choriocapillaris vessel density, out retina and choriocapillaris flow area, and full retina thickness were analyzed in the fovea centered 6 × 6 mm area. The association between OCTA measurements and carotid plaque characteristics in patients with CHD were evaluated.ResultsThe duration of hypertension and DM was significantly longer in CHD patients with carotid plaque than that without (p < 0.001). The mean values for vessel density SCP and DCP (except fovea zone), and choriocapillaris nasal zone were significantly lower in plaque group (p < 0.05). Negative correlations between the carotid plaque width and vessel density SCP and DCP (except fovea zone) (p < 0.05) were also found in this study.ConclusionsIn patients with CHD, carotid plaque, a risk factor and marker of atherosclerosis and stenosis, is significantly and independently associated with retinal and choroidal microvascular changes by OCTA.
Fenofibrate enhances radiotherapy efficacy by elevating HDL levels to induce tumor cell ferroptosis in NSCLC with brain metastasis
Authors: Dong Xiaorong , Bin yawen , kuang bohua , Tong Fan , liu lichao , li huanhuan , Rao Xinrui , peng ling , ding peng 
Published: January 2023

Abstract
The brain is a common site of lung cancer metastasis with an extremely poor prognosis. Improving the efficacy of available therapeutics is very important. By analyzing clinical data, we found that HDL and total cholesterol levels in blood are potentially correlated with the efficacy of brain radiotherapy. And we found that fenofibrate can promote the synthesis of HDL by targeting PPARα and lipidomics results demonstrated that fenofibrate could also alter the intracellular lipid composition of tumor cells and increase the ratio of PUFAs/MUFAs, thus increasing the oxidative substrate for ferroptosis. Thereby promotes radiation-induced ferroptosis in tumor cells. Flow cytometry, immunofluorescence and elisa show that ferroptotic tumor cells further increase the infiltration of CD8 + T cells in the tumor microenvironment and the secretion of IFN-γ. In vivo experiment also verify that combination of fenofibrate and radiotherapy can enhancing the efficacy of immunotherapy. Thus, the combination of fenofibrate and radiotherapy could provide a new therapeutic strategy for non-small cell lung cancer patients with brain metastases.
Extracorporeal shockwave therapy improves pain and function in subjects with chronic low back pain: a systematic review and meta-analysis of randomized clinical trials
Authors: Liu kun , Zhang Qingyu , Chen Lili , Zhang Haoran , Xu Xiqiang , Yuan Zenong , Dong Jun 
Published: January 2023

Abstract
Background: Extracorporeal shock wave therapy (ESWT) has been widely used for pain control in musculoskeletal disorders. Whether ESWT can relieve chronic low back pain and improve lumbar function is still controversial. Therefore, we designed a meta-analysis based on relevant studies to comprehensively analyze and determine the efficacy and safety of ESWT for chronic low back pain.
Methods:PubMed, Embase, Cochrane Library, and Web of Science were systematically searched for randomized controlled trials (RCT) studies on extracorporeal shock wave therapy for chronic low back pain from inception to September 2022. The quality of the included literatures was evaluated according to Cochrane systematic review criteria, relevant data were extracted, and meta-analysis was performed using RevMan 5.4 software.
Results:12 RCTs involving 632 patients were included to this investigation. In terms of pain relief, ESWT was associated with lower VAS scores in patients receiving ESWT in comparison with controls at 4 weeks (WMD =−1.04; 95% CI =−1.44 to −0.65; P <0.001) and 12 weeks (WMD =−0.85; 95% CI =−1.30 to −0.41; P <0.001). In terms of improvement of dysfunction index, ESWT significantly increased ODI score in comparison with control group at 4 weeks (WMD =−4.22; 95% CI =−7.55 to −0.89; P <0.001) and 12 weeks (WMD =−4.51; 95% CI =−8.58 to −0.44; P = 0.03). For mental health, there was no significant difference in the ESWT group compared with the control group after 4 weeks of intervention (SMD =1.17; 95% CI =−0.10 to 2.45; P = 0.07).
Conclusion: ESWT can relieve pain and improve lumbar dysfunction in patients with chronic low back pain, but has no significant effect on patients' mental health.
Boomerang packet testing to mitigate wormhole attack in MANET
Authors: K Rajkumar , Shalinie S mercy 
Published: January 2023

Abstract
MANET is an infrastructure-less wireless technology used in various critical infrastructure areas such as the military environment, disaster management, etc. MANET is also subject to various security breaches. One such attack is the wormhole attack. Wormhole attackers can unleash a great deal of damage like dropping data packets, manipulating data, disrupting routing, etc. In this paper, we have proposed a novel wormhole mitigation security framework. Our security framework utilizes the attack model to detect an active wormhole attack in MANET. The crux of our framework is that an admin node is chosen from a list of trustable nodes. The admin node periodically relays a boomerang packet across the network. The boomerang packet is the packet destined to return to the admin node itself. Based on the state of the boomerang packet, when it returns admin decides if the packet has been subject to a wormhole attack. If it is subject to a wormhole attack, preventive measures are taken to mitigate the attack. We conducted exhaustive experiments in the NS-3.26 simulator and compared the results with state-of-the-art solutions. Our strategy was able to detect the wormhole nodes at an accuracy of 97%. The packet loss rate was also less when compared to other state-of-the-art solutions during the wormhole attack. This was because of the early and accurate detection of the wormhole attack in MANET.
Co-composted faecal sludge as organic fertilizer to restore crude oil- contaminated soil
Authors: Okoh Elechi , Patrick Indianamowei Olaowei , Yelebe Zekieni Robert , Oruabena Bernard 
Published: January 2023

Abstract
Several developmental challenges, including natural resource depletion, environmental degradation, solid waste management, and the dumping of untreated faecal sludge into the environment, are issues facing developing countries and damaging their economic well-being. Crude oil pollution of arable land and water resources concerns several oil-producing communities whose land is degraded daily by oil spills. Although it contains nutrients and organic matter needed for improved plant growth, Faecalwaste poses a severe environmental concern as it also has pathogens. Co-composting is considered a reasonable, low-cost waste treatment option that can allow the recycling of faecal sludge and other organic wastes from various waste streams with the double advantage of combined sanitation, nutrient recovery, and income generation. This work developed a biostimulant for crude oil-polluted soil remediation using dewatered faecal sludge co-composted with organic kitchen waste. By mixing dewatered faecal sludge with organic kitchen waste using structural material (sawdust) as a bulking agent in a co-composting process, a sanitised compost devoid of enteric pathogens was produced. The composting product's quality was assessed by monitoring the composting system's physicochemical parameters. The reduction in faecal indicators was remarkable using sawdust matrix as a structural material, and T.N., T.P., T.K., and C: N ratios were all significant. These results showed the feasibility of co-composting dewatered faecal sludge with kitchen waste and sawdust as a matrix to generate compost usable in agriculture and crude oil-contaminated soil remediation.
First description of NDM-1 and IMP-1 producing carbapenem-resistant Pseudomonas mendocina
Authors: Fang Jianhua , Yang Jie , Kang Xiuhua , Mei Yanfang , Liu Jing , Xiong Xiaofeng , Xiang， Tianxin 
Published: January 2023

Abstract
Objective: To describe NDM-1 and IMP-1 producing carbapenem-resistant Pseudomonas mendocina.
Methods: Antimicrobial susceptibility test was performed on carbapenemase-producing P.mendocinaclinical isolate. Whole genome sequencing data were analyzed using comparative genomics. The virulence of P. mendocina strain was analyzed by string test, serum killing assay and biofilm formation assay. Conjugation experiment and whole genome sequencing (WGS) was used to determine the transferability of plasmid co-producing NDM-1 and IMP-1 genes.
Case presentation: A middle-aged woman's urine culture sample confirmed Pseudomonas Mendoza infection. Piperacillin/tazobactam was discontinued based on the drug susceptibility results. Biapenem in combination with etimicin was used as an anti-infection therapy for a week.
Results: The P. mendocina strain had intrinsic resistance to most clinical antibiotics, including aminoglycosides, beta-lactams,sulfonamides, tetracyclines, aztreonam and fosfomycin. Serum resistance and biofilm array had indicated moderate virulence. The conjugation assay showed that the NDM-1 gene was located on a conjugable plasmid. WGS revealed that the P. mendocina strain had a 5.62832Mb chromosome (62.47% GC content) and a 172.851 Kb plasmid (56.83% GC content). Additionally, it showed that the isolates carried the NDM-1 and IMP-1 resistance genes.
Conclusion: This is the first descriptive study of a P. mendocina strain producing NDM-1 and IMP-1 carbapenemases.The findings of this study suggest that medical staff in clinical and laboratory departments should pay close attention to the isolation, identification, and pathogenecity of the rare bacteria during routine examinations, and immediately adopt infection control measures to prevent its spread.
Hydroxyurea Ulcers of Unusual Location: A Case Report and Review of the Literature
Authors: Mansilla-Polo Miguel , Navarro-Mira Miguel Ángel , Botella-Estrada Rafael 
Published: January 2023

Abstract
Introduction
Hydroxyurea is a cytotoxic drug that has been used for decades for the treatment of various entities, mostly hematological, especially polycythemia vera.
Its side effects are varied, including dermatological ones, ranging from skin xerosis, hyperpigmentation, lesions like dermatomyositis, and even a relationship with premalignant processes (actinic keratosis) and non-melanoma cancer (squamous, basal cell, Merkel, and oral tumors).
Case presentation
In this paper, we report a clinical case of a relatively frequent adverse effect of hydroxyurea, ulcers, but of extraordinary localization and clinical presentation. Specifically, in our patient, the location was both hands, associated dermatomyositis-like lesions and nail hyperpigmentation, skin changes also related to hydroxyurea. The therapeutic response with withdrawal was spectacular.
Conclusions
The association of ulcers with taking hydroxyurea is well known. Most of the time, these appear in the lower limbs, and in patients with chronic vascular pathology. However, in some patients in some patients, it can present atypically. Knowledge of this condition is vitally important for the hematologist and the dermatologist to ensure adequate care.
Sub-national variation in indicators of maternal mortality in Kenya requires targeted interventions to fast-track SDG attainment
Authors: Mwaura Hellen M. , Kamanu Timothy K. , Kulohoma Benard W. 
Published: January 2023

Abstract
Background
One in four deaths among females of reproductive age is maternal or pregnancy related, thereby making maternal mortality a major global health concern. A disproportionate number of these deaths occur in developing countries. In Kenya, maternal mortality ratio (MMR) has declined from 708 to 378 deaths per 100,000 live births between 2000 and 2021. However, the Sustainable Development Goal (SDG-3.1) target is to reduce global MMR to less than 70 deaths per 100,000 live births by 2030. Here, we quantify and highlight indicators that contribute to differentiated MMR across different geographic regions in Kenya. We anticipate that this will inform targeted interventions and resource allocation for each specific region and fast-track SDG-3 attainment.
Methods
We leveraged data from the demographic and health survey for Kenya. The correlation in the patterns of the indicators and MMR across the counties and the regions was analyzed and the cumulative contribution by multiple indicators for each county was determined. We then compared the performance of the regions to the national average by calculating the rate ratios.
Results
Our results highlight how variation in socio-demographic characteristics influence maternal mortality rates across Kenya. We observed a high antenatal clinic attendance rate, but on the contrary very low rates of uptake of modern contraceptives. Infectious diseases (Malaria, TB, and HIV) exhibited an overlap in geographic distribution in coastal counties and counties around lakes. There was a significant correlation between prevalence of malaria and HIV (Pearson’s correlation coefficient r = 0.59), and a moderate positive correlation between prevalence of HIV and TB (Pearson’s correlation coefficient r = 0.41). Gender-based violence during pregnancy was highest in an urban setting (18.1%), and lowest in marginalized rural areas (2.7%). Female genital mutilation had higher rates among those who practice Islam (51.1%), live in rural settings (25.9%), with no education (13%), and in the lowest wealth quintile (6.2%).
Conclusion
These findings suggest a wide spectrum of direct, indirect, cultural and socio-economic factors collectively contributing to elevated MMR. We disaggregate sub-national disparities and highlight that customized interventions for different sub-populations are required to curtail maternal mortality, and accelerate the attainment of the SDG-3.1 target.