bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comprehensive Integrated Dataset on Brazilian Health Facilities: from 2005 to 2021
Authors: Salles Rebecca , Ribeiro Victor de Paula Dornellas , Gritz Raquel , Cardoso Carlos Leonardo Souza , Paixão Balthazar , Carraro Lucas , Cruz Sérgio Ricardo de Borba , Kreischer Vinicius , Bonifácio Carmen Lúcia Corrêa , Saldanha Raphael de Freitas , Souto Gabriel , Miloski Matheus , Zirondi Leandro , Alencar Gizelton Pereira , Alves Ariane Camilo Pinheiro , Neto Nelson Niero , Lima Jefferson da Costa , Pedroso Marcel , Alves Ronaldo Fernandes Santos , Boccolini Patricia de Moraes Mello , Boccolini Cristiano Siqueira 
Published: December 2022

Abstract
Objectives
The National Registry of Healthcare Facilities is a system with the registry of every healthcare facility in Brazil with information on the capacity building and healthcare workforce regarding its public or private nature. Despite being publicly available, it can only be accessed in separated disjoint tables, with different primary units of analysis. The objective is to offer an interoperable dataset containing monthly data from 2005 to 2021 with information on healthcare facilities, including their physical and human resources, services and teams, enriched with municipal information.
Data description
Database with historical data and geographic information for each health facility in Brazil. It is composed by 5 distinct tables, organized according to combinations of time, space, and types of resources, services and teams. This database opens up a range of possibilities for research topics, from case studies in a single health facility and period, analysis of a group of health facilities with characteristics of interest, to a broader study using the entire dataset and aggregated data by municipality. Furthermore, the fact that there is a row for each health facility/month/year facilitates the integration with other datasets from the Brazilian healthcare system. In addition to being a potential object of study in the health area, the dataset is also convenient in data science, especially for studies focused on time series.
On the role of history-dependent adsorbate distribution and metastable states in switchable mesoporous metal-organic frameworks
Authors: Walenszus Francesco , Bon Volodymyr , Evans Jack D. , Krause Simon , Getzschmann Jürgen , Kaskel Stefan , Dvoyashkin Muslim 
Published: December 2022

Abstract
A unique feature of metal-organic frameworks (MOFs) in contrast to rigid nanoporous materials is their structural switchabilty offering a wide range of functionality for sustainable energy storage, separation and sensing applications. This has initiated a series of experimental and theoretical studies predominantly aiming at understanding the thermodynamic conditions to transform and release gas, but the nature of sorption-induced switching transitions is still not fully understood yet. Here we report experimental evidence for fluid metastability and history-dependent states during sorption trigerring the structural change of the framework and leading to a counterintuitive phenomenon of negative gas adsorption (NGA) in flexible MOFs. Preparation of two isoreticular MOFs differing by structural flexibility and performing direct in situ diffusion studies aided by in situ X-ray diffraction, scanning electron microscopy and computational modelling, allowed assessment of n-butane molecular dynamics, phase state, and the framework response and obtaining microscopic picture for each step of the soprtion process.
SARS-CoV-2 viremia but not respiratory viral load is associated with ventilator complications
Authors: Chen Lingye , Olson Lyra B. , Naqvi Ibtehaj A. , Sullenger Bruce A. , Nair Smita K , Que Loretta G. , Denny Thomas N. , Kraft Bryan D. 
Published: December 2022

Abstract
COVID-19 can cause acute respiratory distress syndrome (ARDS) associated with high morbidity and mortality. Previous studies have shown an association between plasma viral load (VL) of severe acute respiratory distress (SARS-Cov2) and disease severity. This study is one of the first to measure endotracheal aspirate (ETA) VL in addition to plasma VL in patients admitted to the medical intensive care unit with COVID-19. Viral load from both plasma and ETA decreased over time. Subjects with high plasma VL experienced a greater number of adverse events, including ventilator-associated pneumonia (VAP), increased number of days on mechanical ventilation, and increased number of days in hospital. There was no association between ETA VL and adverse events.
Knowledge, perception, reasons, and suggested measures for mitigating academic dishonesty among healthcare students in a Nigerian University
Authors: Orok Edidiong , Adeniyi Funmilayo , Williams Tonfamoworio , Dosunmu Oyebode , Ikpe Favour , Orakwe Clifford 
Published: December 2022

AbstractThis study aimed to assess the knowledge, perception, influencing factors as well as suggested strategies to reduce academic dishonesty among healthcare students. A cross-sectional design that employed a self-administered online questionnaire was used to collect data among healthcare students in Afe Babalola University, Ado-Ekiti, Nigeria. Purposive and simple random sampling techniques were used in selecting the respondents. Knowledge was categorised into poor (< 50%), fair (50–69%) and good (≥ 70%) while perception was classified as positive (≥ 50%) and negative (< 50%). Association between student demographics, and perception of academic dishonesty was analysed using Chi-Square and Fisher Exact tests. Differences in knowledge between demographics was analysed using independent sample T-test and One way Analysis of variance. 335 students were enrolled in this study of which 83.3% were female and the mean age of the respondents was 19.33 years. 29.8% and 94.9% of the students showed good knowledge and positive perception of academic dishonesty respectively. There was a significant difference in knowledge based on students’ level of study (p < 0.001) and departments (p < 0.001). Fear of failure (77.0%), social stigma and peer pressure (37.0%) were commonly identified reasons for academic dishonesty among students while strict punishment (18.3%) and proper invigilation (16.2%) were the most suggested strategies (n = 178) to control academic dishonesty among students. Poor to fair knowledge and positive perception towards academic dishonesty was shown by majority of the students. Educational intervention in form of training and proper implementation of suggested strategies is warranted to improve knowledge, reduce misconceptions and ultimately reduce academic dishonest behaviours among students.
The Weinstein transform associated with generalized distributions
Authors: Upadhyay Santosh Kumar , Yadav Sitaram 
Published: December 2022

Abstract
Björck [4], and Hörmander [8], investigated the linear partial differential operators and generalized distributions associated with the Fourier transform by utilizing the convolution properties on the spaces of types Dω(Rn), Eω(Rn), and Sω(Rn). Motivated by above results the present paper examined various properties of the Wein-stein transform over generalized distributions Dω (R+n+1) and other spaces. The convolution properties of generalized distributions associated with the Weinstein transform on space Dω (R+n+1) ) are discussed.
Mathematics Subject Classification (2010). 46F05. 46F10. 46F12. 42A85.
Identification and Experimental Validation of Parkinson’s Disease with Major Depressive Disorder Common Genes
Authors: Wang Huiqing , Dou Shanshan , Gao Wenming , Cheng Baohua , Yan Fuling 
Published: December 2022

Abstract
Parkinson's disease (PD) is the second most common neurodegenerative disease that affects about 10 million people worldwide. Non-motor and motor symptoms usually accompany PD. Major depressive disorder (MDD) is one of the non-motor manifestations of PD it remains unrecognized and undertreated effectively. MDD in PD has complicated pathophysiologies and remains unclear. The study aimed to explore the candidate genes and molecular mechanisms of PD with MDD. PD (GSE6613) and MDD (GSE98793) gene expression profiles were downloaded from Gene Expression Omnibus (GEO). Above all, the data of the two datasets were standardized separately, and differentially expressed genes (DEGs) were obtained by using the Limma package of R. Take the intersection of the two differential genes and remove the genes with inconsistent expression trends. Subsequently, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were investigated to explore the function of the common DEGs. Additionally, the construction of the protein-protein interaction (PPI) network was to search the hub genes, and then the least absolute shrinkage and selection operator (LASSO) regression was used to further identify the key genes. GSE99039 for PD and GSE201332 for MDD were performed to validate the hub genes by the violin plot and receiver operating characteristic (ROC) curve. Last but not least, immune cell dysregulation in PD was investigated by immune cell infiltration. As a result, a total of 45 common genes with the same trend. Functional analysis revealed that they were enriched in neutrophil degranulation, secretory granule membrane, and leukocyte activation. LASSO was performed on 8 candidate hub genes after CytoHubba filtered 14 node genes. Finally, AQP9, SPI1, and RPH3A were validated by GSE99039 and GSE201332. Additionally, the three genes were also detected by the qPCR in vivo model with the same phenomenon. The co-occurrence of PD and MDD can be attributed to AQP9, SPI1, and RPH3A genes. Neutrophils and monocytes infiltration play important roles in the development of PD and MDD. Novel insights may be gained from the findings for the study of mechanisms.
Do the Total Received of Zakat Funds and Total Received of Infak/Alms Funds Affect the Number of Poor Populations? an Evidence from Indonesia
Authors: Sobiyanto Ahmad 
Published: December 2022

Abstract
This research was conducted to find out whether there was any influence from the total receipt of zakat funds and receipt of infaq/alms funds on the number of poor people in Indonesia in 2017-2019. Secondary data comes from the financial reports of the National Amil Zakat Agency or BAZNAS of the Republic of Indonesia and the Central Bureau of Statistics of the Republic of Indonesia for 2017-2021. The results of multiple linear regression indicate that the amount of zakat funds received and the amount of infaq/alms funds received simultaneously has no significant effect on the variable number of poor people in Indonesia. The amount of receipt of zakat funds and the amount of receipt of infaq/alms funds partially have no significant effect on the number of poor people in Indonesia.
Assessment of on-road High Nox Emitters by Using Machine Learning Algorithms for Heavy-duty Vehicles
Authors: KAZAN Filiz , Thiruvengadam Arvind , Besch Marc 
Published: December 2022

Abstract
The aim of this study was to develop a model structure and to train a model based on chassis dynamometer datasets and subsequently use the trained model in conjunction with portable emission measurement system (PEMS) datasets in order to identify vehicles as possible high-NOx emitting vehicles. The long-short term memory (LSTM) model developed based on a single reference vehicle (i.e., Vehicle A) dataset was applied to the entire 12 diesel vehicle PEMS datasets in order to identify high-NOx emitters. The results showed that the vehicles that were manually identified as high emitting vehicles (i.e., control subjects) were also identified by the LSTM model to exceed real-world NOx emissions. Similarly, a random forest (RF) model was developed for a reference CNG vehicle (i.e., Vehicle N) and subsequently applied to 11 CNG vehicles with a 0.2 g/bhp-hr NOx regulation limit using PEMS data in order to identify any possible high NOx emitting vehicles. The results showed that the vehicles that were manually labeled as high emitters were also identified by the RF model to exhibit high real-world NOx emissions beyond any properly working vehicle. The prediction results show that high NOx emitting vehicles had a ratio of predicted versus measured NOx emissions that were lower than unity.
Boundary Lipschitz Regularity and the Hopf Lemma for Fully Nonlinear Elliptic Equations
Authors: Lian Yuanyuan , Zhang Kai 
Published: December 2022

Abstract
In this paper, we study the boundary regularity for viscosity solutions of fully non-linear elliptic equations. We use a unified, simple method to prove that if the domain Ω satisfies the exterior C1,Dini condition at x0 ∈ ∂Ω (see Definition 1.2), the solution is Lipschitz continuous at x0; if Ω satisfies the interior C1,Dini condition at x0 (see Definition 1.4), the Hopf lemma holds at x0. The key idea is that the curved boundaries are regarded as perturbations of a hyperplane. Moreover, we show that the C1,Dini conditions are optimal.
2010 MSC: 35B65, 35J25, 35J60, 35D40
How to adjust the expected waiting time to improve patients' satisfaction？
Authors: Zhang Hui , Ma Wei-Min , Zhu Jing-jing , Wang Li , Guo Zhenjie , Chen xiangtang 
Published: December 2022

Abstract
Background
Long waiting time in hospital leads to patients’ low satisfaction. In addition to reducing the actual waiting time (AWT), we can also improve satisfaction by adjusting the expected waiting time (EWT). Then, what degree should medical institutions adjust patients' EWT to in order to improve patient’s satisfaction more effectively?
Methods
A total of 303 patients who were treated by the same doctor from August 2021 to April 2022 voluntarily participated in this study. The patients were randomly divided into six groups: a control group (n = 45) and five experimental groups (n = 252). Each group answered different questionnaires to explore the impact of different degrees of EWT extension on patient’s satisfaction. Each participant only participated in filling out one questionnaire. 297 valid questionnaires were obtained from the 303 questionnaires given.
Results
The experimental groups had significant differences between the initial EWT (T0) and extended EWT (T1) under the effect of unfavorable information (20.0 [10.0, 30.0] vs. 30.0 [10.0, 50.0], Z = -4.086, P < 0.001). There was no significant difference between sex, age, education level and hospital visit history (χ2 = 3.198, P = 0.270; χ2 = 2.177, P = 0.903; χ2 = 3.988, P = 0.678; χ2 = 3.979, P = 0.264) in extended EWT (T1). Compared with the control group, significant differences were found in patient’s satisfaction when T1 = 80 min (χ2 = 13.511, P = 0.004), T1 = 90 min (χ2 = 12.207, P = 0.007) and T1 = 100 min (χ2 = 12.941, P = 0.005). However, no significant difference was found when T1 = 70 min (χ2 = 7.747, P = 0.052) and T1 = 110 min (χ2 = 4.382, P = 0.223). When T1 = 90 min (T1 = Ta), 69.4% (34/49) of the individuals felt “very satisfied”. This proportion is not only significantly higher than that of the control group (34/ 49 vs. 19/52, χ2 = 10.916, P = 0.001), but also the highest among all groups.
Conclusions
Providing unfavorable information prompts can extend the EWT, but the extension needs to be based on the actual number of patients. Only when the extended EWT is close to the AWT can the patients’ satisfaction level be remarkably improved. Therefore, medical institutions can adjust the EWT of patient’s through information release according to the AWT of hospitals to improve patient’s satisfaction.
Hemispheric asymmetries and brain size: A cross-species meta-regression
Authors: Ocklenburg Sebastian , Basbasse Yasmin El , Ströckens Felix , Müller-Alcazar Anett 
Published: December 2022

Abstract
Hemispheric asymmetries differ considerably across species, but the neurophysiological base of this variation is unclear. It has been suggested that hemispheric asymmetries evolved to bypass interhemispheric conduction delay when performing time critical tasks. This implies that large brains should be more asymmetric. We performed preregistered cross-species meta-regressions with brain mass and neuron number as predictors for limb preferences, a behavioral marker of hemispheric asymmetries. Brain mass and neuron number showed positive associations with rightward limb preferences but negative associations with leftward limb preferences. No significant associations were found for ambilaterality. These results are only partly in line with the idea that conduction delay is the critical factor that drives the evolution of hemispheric asymmetries. They suggest that larger-brained species tend to shift towards more right-lateralized individuals. Therefore, the need for coordination of lateralized responses in social species needs to be considered in the context of the evolution of hemispheric asymmetries.
Purinergic Signaling In Vivo Phenotypic Validation of Adenosine Receptor-Dependent Activity of Non-adenosine Drugs
Authors: Xiao Cuiying , Gavrilova Oksana , Liu Naili , Lewicki Sarah A. , Reitman Marc L. , Jacobson Kenneth A. 
Published: December 2022

Abstract
Some non-adenosinergic drugs are reported to also act through adenosine receptors (ARs). We used mouse hypothermia, which can be induced by agonism at any of the four ARs, as an in vivo screen for adenosinergic effects. An AR contribution was identified when a drug caused hypothermia in wild type mice that was diminished in mice lacking all four ARs (quadruple knockout, QKO). Alternatively, an adenosinergic effect was identified if a drug potentiated adenosine-induced hypothermia. Four drugs (dipyridamole, nimodipine, cilostazol, cyclosporin A) increased the hypothermia caused by adenosine. Dipyridamole and nimodipine probably achieved this by inhibition of adenosine clearance via ENT1. Two drugs (cannabidiol, canrenoate) did not cause hypothermia in wild type mice. Four other drugs (nifedipine, ranolazine, ketamine, ethanol) caused hypothermia, but the hypothermia was unchanged in QKO mice indicating non-adenosinergic mechanisms. Zinc chloride caused hypothermia and hypoactivity; the hypoactivity was blunted in the QKO mice. Interestingly, the antidepressant amitriptyline caused hypothermia in wild type mice that was amplified in the QKO mice. Thus, we have identified adenosine-related effects for some drugs, while other candidates do not affect adenosine signaling by this in vivo assay. The adenosine-modulating drugs could be considered for repurposing based on predicted effects on AR activation.
Learning Control of a Laser-Driven Locomotive Microrobot for Dry Environments
Authors: Yang Zhong , Alqatamin Moath , Sherehiy Andriy , Zhang Ruoshi , Hudibi Mojtaba Al , Chowdhury Sri Sukanta , Popa Dan O. 
Published: December 2022

Abstract
In this paper, we introduce the SerpenBot, a microrobot smaller than 1mm in size, powered by laser energy, and designed to operate in dry environments. The microrobot achieves locomotion on a Si substrate by selective coupling of laser energy between two legs that move the robot forward and steer it. The laser energy coupling mechanism is achieved by selective energy-time irradiation of the microrobot’s body and legs to initiate the gait. Complex multi-physics models developed in our past work are simplified to a differential drive kinematic model that approximates the robot behavior and is used to formulate a deep learning controller that can steer the robot to desired locations on the silicon substrate. Simulations predict the robot position regulation achieved by deep learning of the inverse robot Jacobian. Experimental results are presented confirming that the microrobot can be automatically steered to a goal location.
Economic Giants of the East and Debt Accumulation in Sub Saharan Africa
Authors: Gamette Pius , Avorkpo Eric Atsu , Opoku Alexander 
Published: December 2022

Abstract
This study investigates the level to which Chinese Loan Financiers’ contribute to debt pile up in Sub Sahara Africa countries (SSA). Using a panel data from 45 SSA countries from 2000 to 2017 and adopting the Pooled Ordinary Least Sqaure (OLS) regression method, the findings suggested that credit disbursement from Commercial Development Bank (CDB) and Suppliers Credit to SSA countries each has a significant positive impact on SSA debt accumlation. However, credit from Eximbank has a significant negative impact on debt accumulation in SSA. In terms of sectorial contribution to debt stock, the Envrionmental sector was the highest recipient of Chinese loans compared to Multisector, Food and Unallocated sectors in SSA. The useful implication is that to minimise debt stock in SSA countries, policy makers within the sub region must efficiently take debt miimising decisions after analysing the tradeoff between pressing development needs and the debt accumulation. As an input to existing literature, this study makes available an imperative contribution for deliberations on the relevance of external borrowing and debt accumulation in SSA.
JEL: C23, G51, H6
Fast start-up and enhancement of CANON process for the low-strength wastewater treatment: tactic and action of ultrasonic
Authors: Zhang Li , Luo Di , Huang Diannan , Qian Jie , Ma Xingguan , Zhang Lei , Li Jiaxin , Gao Yunan 
Published: December 2022

Abstract
In this study, the CANON (Completely Autotrophic Nitrogen-removal Over Nitrite) process was successfully started-up inoculate by anammox sludge which was under cold preservation for three-months, and the stable operation of CANON process for low-strength wastewater treatment were achieved through ultrasonic enhancement. In accordance with the optimal parameters determined in batch tests, which controlled (DO=0.3-1.5mg/L, HRT=4.0-12h and pH 7.5±0.3) three critical factors to repressed the NOB (Nitrite-Oxidizing Bacteria). The CANON process was started-up within 15 days. Subsequently, effect of ultrasonic was gradually added to the CANON system to investigate its impact. Results showed that, through ultrasonic (intensity of 0.3 w/cm2, act on time 4 min/d), the NH4 +-N and TN removal efficiency were 95% and 76.7% in the CANON process(~50 mg N.L-1), respectively. The 16S rRNA analysis showed that the abundance of dominanted phylum has remarkablely conversion after ultrasonic enhancement. The relative abundance of AOB were increased form 12.15% to 24.14%. Moreover, the NOB were decreased from 2.97% to 1.64%. The relative abundance of Candidatus brocadia and Candidatus Kuenenia were accounted for 27.07% and 11.52%, respectively. The Nitrosomonas was also enriched to 12.15% significantly. In general, a certain intensity of ultrasonic (intensity of 0.3 w/cm2, act on time 4 min/d) could provides an effective promotion for AOB and suppression for NOB. The results provide technical assistance for the starting-up and stably performance in the mainstream CANON system.