bluuebunny/crossref_metadata_2025_split huggingface dataset:
Musical participation and positive youth development in middle school
Authors: Ilari Beatriz , Cho Eun 
Published: January 2023

IntroductionMusic is central in the lives of adolescents. While listening is usually the most common form of engagement, many adolescents also learn music formally by participating in school-based and extracurricular programs. This study examined positive youth development (PYD), school connectedness (SC), and hopeful future expectations (HFE) in middle school students (N = 120) with four levels of musical participation in school-based and extracurricular music programs. Levels of participation were based on students’ engagement in different music programs, including the Virtual Middle School Music Enrichment (VMSME), a tuition-free, extracurricular program that focuses on popular music education and virtual learning. We also investigated student listening preferences, musical tuition, and daily instrumental practicing.MethodStudy participants completed an anonymous, online survey that contained five self-report measures including the very-brief form of the PYD questionnaire, a scale of school connectedness, and a scale of HFE.ResultsFindings revealed significant differences in PYD scores by grade and gender, and associations between levels of musical participation and competence, a PYD component. Liking music and participation in extracurricular activities predicted scores on SC, and starting formal music education before age 8 predicted scores in HFE. We also found VMSME students to stem from neighborhoods with lower HDI than students in the other study groups, which points to issues of access to formal music education.DiscussionFindings are discussed in light of earlier research on PYD, extracurricular activities in adolescence, the ubiquity and functions of music in adolescence, and deficit thinking in education.
Short-term outcomes of physical activity counseling in in-patients with Major Depressive Disorder: Results from the PACINPAT randomized controlled trial
Authors: Cody Robyn , Beck Johannes , Brand Serge , Donath Lars , Faude Oliver , Hatzinger Martin , Imboden Christian , Kreppke Jan-Niklas , Lang Undine E. , Ludyga Sebastian , Mans Sarah , Mikoteit Thorsten , Oswald Anja , Schweinfurth Nina , Zahner Lukas , Gerber Markus 
Published: January 2023

IntroductionA physical activity counseling intervention based on a motivation-volition model was developed and delivered to in-patients with Major Depressive Disorders with the aim of increasing lifestyle physical activity. The aim of this study is to evaluate the short-term outcomes of this intervention.MethodsA multi-center randomized controlled trial was conducted in four Swiss psychiatric clinics. Adults who were initially insufficiently physically active and were diagnosed with Major Depressive Disorder according to ICD-10 were recruited. The sample consisted of 113 participants in the intervention group (Mage = 42 years, 56% women) and 107 in the control group (Mage = 40 years, 49% women). Motivation and volition determinants of physical activity were assessed with questionnaires. Implicit attitudes were assessed with an Implicit Association Test. Physical activity was self-reported and measured with hip-worn accelerometers over 7 consecutive days starting on the day following the data collection.ResultsAccording to accelerometer measures, step count decreased on average 1,323 steps less per day (95% CI = −2,215 to −431, p &lt; 0.01) over time in the intervention group compared to the control group. A trend was recognized indicating that moderate-to-vigorous physical activity decreased on average 8.37 min less per day (95% CI = −16.98 to 0.23, p &lt; 0.06) over time in the intervention group compared to the control group. The initial phase of the intervention does not seem to have affected motivational and volitional determinants of and implicit attitudes toward physical activity.ConclusionPhysical activity counseling may be considered an important factor in the transition from in-patient treatment. Methods to optimize the intervention during this period could be further explored to fulfill the potential of this opportunity.Clinical trial registrationhttps://www.isrctn.com/ISRCTN10469580, identifier ISRCTN10469580.
Virtual reality-based monitoring test for MCI: A multicenter feasibility study
Authors: Jang Sooah , Choi Sun-Woo , Son Sang Joon , Oh Jooyoung , Ha Junghee , Kim Woo Jung , Roh Hyun Woong , Kim Keun You , Lee San , Jung Eunjin , Cha Woojin , Chae Heonjoo , Kang Suzi , Kwon Ji Hye , Kim In-Young , Lee Ju-Yeal , Shin Hyun Kyung , Ryu Jin Sun , Ahn Ryunsup , Hong Chang Hyung , Seok Jeong-Ho 
Published: January 2023

ObjectivesAs the significance of the early diagnosis of mild cognitive impairment (MCI) has emerged, it is necessary to develop corresponding screening tools with high ecological validity and feasible biomarkers. Virtual reality (VR)-based cognitive assessment program, which is close to the daily life of the older adults, can be suitable screening tools for MCI with ecological validity and accessibility. Meanwhile, dehydroepiandrosterone (DHEA) has been observed at a low concentration in the older adults with dementia or cognitive decline, indicating its potential as a biomarker of MCI. This study aimed to determine the efficacy and usability of a VR cognitive assessment program and salivary DHEA for screening MCI.MethodsThe VR cognitive assessment program and the traditional Montreal Cognitive Assessment (MOCA) test were performed on 12 patients with MCI and 108 healthy older adults. The VR program operates in a situation of caring for a grandchild, and evaluates the memory, attention, visuospatial, and executive functions. An analysis of covariance (ANCOVA), a partial correlation analysis, and receiving operating characteristic (ROC) curve analysis were conducted for statistical analysis.ResultsAccording to the ANCOVA, no significant difference in MOCA scores was found between the normal and MCI groups (F = 2.36, p = 0.127). However, the VR total score of the MCI group was significantly lower than that of the normal group (F = 8.674, p = 0.004). There was a significant correlation between the MOCA and VR scores in the total and matched subdomain scores. The ROC curve analysis also showed a larger area under the curve (AUC) for the VR test (0.765) than for the MOCA test (0.598), and the sensitivity and specificity of the VR program were 0.833 and 0.722, respectively. Salivary DHEA was correlated with VR total (R2 = 0.082, p = 0.01) and attention scores (R2 = 0.086, p = 0.009).ConclusionThe VR cognitive test was as effective as the traditional MOCA test in the MCI classification and safe enough for older adults to perform, indicating its potential as a diagnostic tool. It has also been shown that salivary DHEA can be used as a biomarker for MCI.
The association between current smoking and binge drinking among adults: A systematic review and meta-analysis of cross-sectional studies
Authors: Molaeipour Leila , Ghalandari Maryam , Kangavari Hajar Nazari , Alizadeh Zeinab , Jafari Elahe , Gholami Fatemeh , Ghahremanzadeh Neda , Safari Shiva , Mohseni Vahideh , Shahsavan Masoumeh , Motevalian Seyed Abbas 
Published: January 2023

BackgroundThe substantial increasing trend of binge drinking is a global alarm. Our aim was to undertake a systematic review and meta-analysis of cross-sectional studies to explore the association of current smoking with binge drinking among adults.MethodsWe systematically searched Web of Knowledge; PubMed; Scopus; Embase and Ovid (MEDLINE, EMBASE, PsycARTICLES, PsycINFO, PsycEXTRA, and PsycTests) (from inception to 27 May 2020) databases to identify cross-sectional studies of the association between current smoking and binge drinking. Study screening, data extraction, and methodological quality assessment were all carried out by two independent authors. Adjusted odds ratio (AOR) was pooled with 95% confidence intervals (CI) using random effects model in the meta-analysis, followed by the investigation of the heterogeneity via Q-test and I2 statistic. We assessed publication bias using a funnel plot, the Egger’s, and Begg’s tests.ResultsWe identified 3,171 studies and included nine cross-sectional studies with 64,516 participants. A significant association was found between current smoking and binge drinking among both genders (AOR = 2.97; 95% CI = 1.98 to 4.45; I2 = 90.5%). Subgroup analysis showed that this association among women, men, Caucasians, and Asians/Africans were (AOR = 3.68; 95% CI = 1.03 to 13.18; I2 = 98.9%), (AOR = 2.53; 95% CI = 1.87 to 3.42; I2 = 73.1%), (AOR = 1.36; 95% CI: 1.01–1.83, I2 = 47.4%), and (AOR = 3.93; 95% CI: 2.99–5.17, I2 = 61.3%), respectively. There was no evidence of publication bias.ConclusionCurrent smoking is associated with binge drinking and can be used for identifying and screening binge drinkers. Moreover, this association is stronger among men, and Asians/Africans. This meta-analysis estimation was limited to English-language studies, and the full text of about 3.5% of reports for retrieval was not found, then generalization of the results should be done with caution.
Travel scenario workshops for geographical accessibility modeling of health services: A transdisciplinary evaluation study
Authors: Molenaar Lotte , Hierink Fleur , Brun Michel , Monet Jean-Pierre , Ray Nicolas 
Published: January 2023

IntroductionLimited geographical access to quality Emergency Obstetric and Newborn Care (EmONC) is a major driver of high maternal mortality. Geographic access to EmONC facilities is identified by the global community as a critical issue for reducing maternal mortality and is proposed as a global indicator by the Ending Preventable Maternal Mortality (EPMM) initiative. Geographic accessibility models can provide insight into the population that lacks adequate access and on the optimal distribution of facilities and resources. Travel scenarios (i.e., modes and speed of transport) used to compute geographical access to healthcare are a key input to these models and should approximate reality as much as possible. This study explores strategies to optimize and harmonize knowledge elicitation practices for developing travel scenarios.MethodsKnowledge elicitation practices for travel scenario workshops (TSW) were studied in 14 African and South-Asian countries where the United Nations Population Fund supported ministries of health and governments in strengthening networks of EmONC facilities. This was done through a mixed methods evaluation study following a transdisciplinary approach, applying the four phases of the Interactive Learning and Action methodology: exploration, in-depth, integration, and prioritization and action planning. Data was collected in November 2020–June 2021 and involved scoping activities, stakeholder identification, semi-structured interviews (N = 9), an evaluation survey (N = 31), and two co-creating focus group discussions (N = 8).ResultsEstimating realistic travel speeds and limited time for the workshop were considered as the largest barriers. The identified opportunities were inclusively prioritized, whereby preparation; a favorable composition of attendees; validation practices; and evaluation were anticipated to be the most promising improvement strategies, explaining their central place on the co-developed initial standard operating procedure (SOP) for future TSWs. Mostly extensive preparation—both on the side of the organization and the attendees—was anticipated to address nearly all of the identified TSW challenges.ConclusionThis study showed that the different identified stakeholders had contradicting, complementing and overlapping ideas about strategies to optimize and harmonize TSWs. Yet, an initial SOP was inclusively developed, emphasizing practices for before, during and after each TSW. This SOP is not only relevant in the context of the UNFPA EmONC development approach, but also for monitoring the newly launched EPMM indicator and even in the broader field of geographic accessibility modeling.
Relationship between self-care compliance, trust, and satisfaction among hypertensive patients in China
Authors: Zhou Chi , Chen Jingchun , Tan Fang , Lai Sihong , Li Xu , Pu Ke , Wu Jiahui , Dong Yin , Zhao Falin 
Published: January 2023

IntroductionHypertension is a growing public health concern worldwide. It is a leading risk factor for all-cause mortality and may lead to complications such as cardiovascular disease, stroke, and kidney failure. Poor compliance of hypertensive patients is one of the major barriers to controlling high blood pressure. Compliance is not ideal among Chinese patients, and increasing patient self-care compliance with hypertension is necessary.MethodsThis article analyzes the status of self-care compliance, trust, and satisfaction among Chinese hypertensive patients using cross-sectional data from Zhejiang Province. We use a multi-group structural equation model (MGSEM) to compare the interrelationships across genders.ResultsThe study's findings show that the average trust, satisfaction, and compliance scores are 3.92 ± 0.55, 3.98 ± 0.61, and 3.33 ± 0.41, respectively. Female patients exhibit higher average total scores for trust and compliance than male patients. The SEM results indicate that trust has a direct positive association with compliance [β = 0.242, 95% CI: (0.068, 0.402)] and satisfaction [β = 0.260, 95% CI: (0.145, 0.367)], while their satisfaction is not directly associated with compliance. The results of MGSEM show that trust has an indirect effect on compliance in the male group through satisfaction [β = 0.051, P &lt; 0.05, 95% CI: (0.012, 0.116)]. In the female group, trust has a direct effect on satisfaction [β = 0.235, P &lt; 0.05, 95% CI: (0.041, 0.406)] and compliance [β = 0.319, P &lt; 0.01, 95% CI: (0.086, 0.574)].DiscussionThis study reveals the mechanisms of self-care compliance, trust, and satisfaction among Chinese hypertensive patients. Its findings may serve as a reference for guiding primary healthcare providers to improve hypertension patients' compliance and implement gender-targeted health interventions.
Artificial intelligence breast ultrasound and handheld ultrasound in the BI-RADS categorization of breast lesions: A pilot head to head comparison study in screening program
Authors: Huang Xiaoxi , Qiu Youhui , Bao Fangfang , Wang Juanhua , Lin Caifeng , Lin Yan , Wu Jianhang , Yang Haomin 
Published: January 2023

BackgroundArtificial intelligence breast ultrasound diagnostic system (AIBUS) has been introduced as an alternative approach for handheld ultrasound (HHUS), while their results in BI-RADS categorization has not been compared.MethodsThis pilot study was based on a screening program conducted from May 2020 to October 2020 in southeast China. All the participants who received both HHUS and AIBUS were included in the study (N = 344). The ultrasound videos after AIBUS scanning were independently watched by a senior radiologist and a junior radiologist. Agreement rate and weighted Kappa value were used to compare their results in BI-RADS categorization with HHUS.ResultsThe detection rate of breast nodules by HHUS was 14.83%, while the detection rates were 34.01% for AIBUS videos watched by a senior radiologist and 35.76% when watched by a junior radiologist. After AIBUS scanning, the weighted Kappa value for BI-RADS categorization between videos watched by senior radiologists and HHUS was 0.497 (p &lt; 0.001) with an agreement rate of 78.8%, indicating its potential use in breast cancer screening. However, the Kappa value of AIBUS videos watched by junior radiologist was 0.39, when comparing to HHUS.ConclusionAIBUS breast scan can obtain relatively clear images and detect more breast nodules. The results of AIBUS scanning watched by senior radiologists are moderately consistent with HHUS and might be used in screening practice, especially in primary health care with limited numbers of radiologists.
Remote mapping of leafy spurge (Euphorbia esula, L.) in Northwestern Colorado
Authors: Mattilio Chloe M. , Tekiela Daniel R. , Norton Urszula 
Published: January 2023

Leafy spurge (Euphorbia esula L.) has been introduced to the Yampa River in Northwestern Colorado for over 40 years and flood and runoff events transport leafy spurge propagules onto adjacent landscapes. The spread of leafy spurge beyond the river channels has yet to be mapped and recorded, and this research was conducted to map leafy spurge occurrence in the Yampa River Valley. Significant stakeholder mapping efforts took place in the summer of 2019–2021, leading to excellent spatial data on leafy spurge presence and absence along the main channel. In summer 2019, multispectral SPOT seven satellite imagery, stakeholder ground mapping efforts, and bright yellow-green leafy spurge bracts were used to interpret imagery, identify dense, unobscured patches of leafy spurge, and digitize them. Spectral signatures from training samples for leafy spurge and other land cover classes (generalized as “not leafy spurge”) were then used to train a Random Forest machine learning classification. In the summer of 2021, generated classification maps were compared to multispectral satellite imagery and stakeholder ground mapped leafy spurge presence. Mismatches were identified, and 271 validation locations were identified, navigated to, and evaluated for leafy spurge presence. Leafy spurge training samples were classified with 96% accuracy. Correctly classified leafy spurge locations had higher leafy spurge coverage and lower overstory canopy than missed leafy spurge locations. Leafy spurge growing beneath shrub canopy or growing as individual plants along the riverbanks were more likely to be missed. A frequency analysis for other plant species found at validation locations determined that smooth brome (Bromus inermis Leyss.), dandelion (Taraxacum officinale L.), and willow (Salix sp.) were most frequently misclassified as leafy spurge. In conclusion, multispectral satellite imagery was useful at remote detection of leafy spurge in open areas with dense leafy spurge coverage, but more work must be done for identification of sparse and diffuse leafy spurge infestations.
Transnational migrants' philanthropy: Its forms, operations, and implications from the perspectives of Ghanaian residents in Europe
Authors: DeSouza Mercy , Osei Onallia Esther , Idemudia Erhabor Sunday 
Published: January 2023

IntroductionWith the emergence of transnational migration studies in the 1990's, migration studies became involved in showing how migrants maintain transnational connections through money and non-monetary philanthropic contributions in their origin countries. However, there is little evidence about the interconnections between different forms of migrants' philanthropy and how they are developed and sustained over time across international borders.MethodsThis work investigates individual and groups transnational philanthropy and shows how migrants become involved in these forms of philanthropy, highlighting some changes therein over time. We relied on fifty semistructured interviews and six focus group discussions conducted with Ghanaians in the Netherlands, Italy and Germany.Results and discussionOur thematic analyses confirm that transnational migrant philanthropy is about fulfilling certain “moral obligations,” to derive a sense of belonging “here” (destinations) and “there” (origins). In performing the self, religious or culturally imposed sense of responsibility for human welfare and institutional development in the home country, Ghana, involved migrants overcome some challenges. For transnational migrant philanthropy to sustain itself, studied migrants think origin country governments must take necessary steps to remove structural obstacles like tedious procedures for clearing philanthropic goods at the ports and harbors. Involved migrants also suggested a need for a more organized platform to collect relevant information on potential beneficiary needs for their preparations to “give back” to their homeland.
Development, Validation, and Application of a Simple and Rugged HPLC Method for Boswellic Acids for a Comparative Study of Their Abundance in Different Species of Boswellia Gum Resins
Authors: Asteggiano Alberto , Curatolo Loris , Schiavo Valentina , Occhipinti Andrea , Medana Claudio 
Published: January 2023

The resin of Boswellia plant species has been used since ancient times for its several bio-active curative effects. In modern times, extracts of this resin are still widely commercialized on the food supplements and nutraceuticals market. Nowadays the legislation on botanical extracts and the increasing demand for their safety and traceability are setting new standards for their chemical characterization. In this work we present an easy, feasible and rugged HPLC-UV-based approach for the quantitation of boswellic acids in food-supplement-grade resin extracts of Boswellia plant species. This method can be used for quality control purposes as well as for studying their differences in regional origin, years of harvesting and species-related differences. The method employs a C18 (3 × 150 mm, 3 µm) analytical HPLC column, and the separation is carried out through a gradient of acetonitrile/water with 0.1% formic acid. The method was validated following the ICH guidelines and used to quantitate different samples of commercial resin of Boswellia carteri and serrata together with other samples from unknown species. The six known boswellic acids were identified and quantified in all the analyzed samples. The results were used to build a multivariate model to graphically appreciate their difference through their clustering. The model was then augmented by adding further quantitation data for boswellic acids belonging to different species of Boswellia obtained by another scientific publications to increase the number of studied samples.
LINC00941 Promotes Cell Malignant Behavior and Is One of Five Costimulatory Molecule-Related lncRNAs That Predict Prognosis in Renal Clear Cell Carcinoma
Authors: Pan Huafeng , Wei Wei , Fu Guanghou , Pan Jiaren , Jin Baiye 
Published: January 2023

Background and Objectives: A significant role was played by costimulatory molecules in renal cancer. However, the lncRNAs regulating costimulatory molecules have not been fully investigated. Materials and Methods: Data from the next-sequence file and clinical data were downloaded from the Cancer Genome Atlas (TCGA) database. All analyses were conducted using the R and GraphPad Prism software. Results: A total of 1736 costimulatory molecule-related lncRNAs were determined under the threshold of |Cor| > 0.5 and p-value < 0.001. Furthermore, a prognosis prediction signature consisting of five lncRNAs: LINC00941, AC016773.1, AL162171.1, HOTAIRM1, and AL109741.1 was established with great prediction ability. By combining risk score and clinical parameters, a nomogram plot was constructed for better clinical practice. A biological enrichment analysis indicated that E2F targets, coagulation, IL6/JAK/STAT3 signaling, G2/M checkpoint, and allograft rejection pathways were activated in high-risk patients. Furthermore, a higher infiltration level of resting CD4+ T cell, M2 macrophage, and resting mast cells, while a lower CD8+ T cell infiltration was observed in high-risk patients. It is worthy of note that, low-risk patients might respond better to PD-1 checkpoint therapy. A correlation analysis of LINC00941 revealed that it was positively correlated with Th2 cells, Th1 cells, macrophages, and Treg cells, but negatively correlated with Th17 cells. A pathway enrichment analysis indicated that the pathways of the inflammatory response, G2M checkpoint, and IL6/JAK/STAT3 signaling were significantly activated in patients with high LINC00941 expression. In vitro experiments indicated that LINC00941 can enhance the malignant biological behaviors of renal cancer cells. Conclusions: Our study established a costimulatory molecule-related lncRNAs-based prognosis model with a great prediction prognosis. In addition, LINC00941 could enhance the malignant biological behaviors of renal cancer cells.