bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deficiencies in the Recognition and Reporting of Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus; A Hungarian Nationwide Analysis
Authors: Ladányi Erzsébet , Salfer Balázs , Balla József , Kárpáti István , Reusz György , Szabó Lilla , Andriska Péter , Németh László , Wittmann István , Laczy Boglárka 
Published: August 2023

Objectives: Recognition of chronic kidney disease (CKD) is crucial in type 2 diabetes mellitus (T2DM). We conducted a nationwide epidemiological study to evaluate T2DM-associated CKD in Hungary between 2016 and 2020.Methods: Annual incidence and prevalence rates of registered CKD amongst all pharmacologically treated T2DM patients were analyzed in different age-groups by the central database of the Hungarian Health Insurance Fund Management. Statistical methods included Poisson regression, Bonferroni test, Chi-square test.Results: We found 499,029 T2DM patients and 48,902 CKD patients in 2016, and 586,075 T2DM patients and 38,347 CKD patients in 2020. The majority of all prevalent T2DM and CKD patients were older (aged 60–69 years: 34.1% and 25.8%; ≥70 years: 36.1% and 64.4%, respectively). The annual incidence of T2DM and incidence rates of CKD in T2DM decreased in 2017–2020 (p &lt; 0.001). The annual prevalence of T2DM increased (p &lt; 0.01), the prevalence rates of CKD in T2DM were low and decreased from 9.8% to 6.5% in 2016–2020 (p &lt; 0.001).Conclusion: Incidence and prevalence of T2DM-associated CKD decreased significantly in Hungary in 2016–2020. Lower prevalence rates of CKD may suggest under-recognition and/or under-reporting.
Evaluation of Bacillus spp. as Potent Probiotics with Reduction in AHPND-Related Mortality and Facilitating Growth Performance of Pacific White Shrimp (Litopenaeus vannamei) Farms
Authors: Proespraiwong Porranee , Mavichak Rapeepat , Imaizumi Kentaro , Hirono Ikuo , Unajak Sasimanas 
Published: August 2023

Acute hepatopancreatic necrosis disease (AHPND) is a serious bacterial disease affecting shrimp aquaculture worldwide. In this study, natural microbes were used in disease prevention and control. Probiotics derived from Bacillus spp. were isolated from the stomachs of AHPND-surviving Pacific white shrimp Litopenaeus vannamei (22 isolates) and mangrove forest soil near the shrimp farms (10 isolates). Bacillus spp. were genetically identified and characterized based on the availability of antimicrobial peptide (AMP)-related genes. The phenotypic characterization of all Bacillus spp. was determined based on their capability to inhibit AHPND-causing strains of Vibrio parahaemolyticus (VPAHPND). The results showed that Bacillus spp. without AMP-related genes were incapable of inhibiting VPAHPND in vitro, while other Bacillus spp. harboring at least two AMP-related genes exhibited diverse inhibition activities. Interestingly, K3 [B. subtilis (srfAA+ and bacA+)], isolated from shrimp, exerted remarkable inhibition against VPAHPND (80% survival) in Pacific white shrimp and maintained a reduction in shrimp mortality within different ranges of salinity (75–95% survival). Moreover, with different strains of VPAHPND, B. subtilis (K3) showed outstanding protection, and the survival rate of shrimp remained stable among the tested groups (80–95% survival). Thus, B. subtilis (K3) was further used to determine its efficiency in shrimp farms in different locations of Vietnam. Lower disease occurrences (2 ponds out of 30 ponds) and greater production efficiency were noticeable in the B. subtilis (K3)-treated farms. Taking the results of this study together, the heat-shock isolation and genotypic-phenotypic characterization of Bacillus spp. enable the selection of probiotics that control AHPND in Pacific white shrimp. Consequently, greater disease prevention and growth performance were affirmed to be beneficial in the use of these probiotics in shrimp cultivation, which will sustain shrimp aquaculture and be environmentally friendly.
Impact of Diabetic Lesions on Pathology, Treatment, and Outcomes of Glomerular Diseases
Authors: Kim Young Ho , Saha Manish K. , Hu Yichun , Kumar Srikar , Poulton Caroline J. , Hogan Susan L. , Nachman Patrick , Jennette J. Charles , Nast Cynthia C. , Mottl Amy K. 
Published: August 2023

Key Points

People with glomerular disease (GD) and comorbid diabetes have similar baseline characteristics irrespective of superimposed diabetic lesions.Immunosuppression for GD with comorbid diabetes is the same regardless of superimposed diabetic glomerular lesions.ESKD or death is more rapid in GD and comorbid diabetes only in the presence of moderate-severe diabetic glomerular lesions.

Background
We aimed to evaluate whether concomitant diabetic glomerulosclerosis (DGS) and its severity affect the treatment and outcomes of primary glomerular diseases (GDs) with comorbid diabetes.

Methods
We conducted a retrospective review of people with diabetes and GD. We searched the GD Collaborative Network for biopsies from 2008 to 2015 among persons with diabetes and any of the following diagnoses: FSGS, IgA nephropathy, minimal change disease, membranous nephropathy, or antineutrophil cytoplasmic autoantibody GN. Data were abstracted from health records and histologic diabetic glomerular class scored. The primary composite end point was ESKD or death. Multivariable Cox regression models tested whether any or the severity of diabetes histopathology affected the primary end point.

Results
Data from 134 cases were available for analysis (78 DGS+GD and 56 GD alone). Diabetes duration and glycemic control were similar between the two groups (P = 0.2; P = 0.09, respectively). Use of immunosuppression did not differ between the two groups (P = 0.3). The composite end point was significantly higher in DGS+GD (22.5 cases per 100 person-years [95% confidence interval (CI), 16.6 to 30.5]) versus GD alone (10.2 cases per 100 person-years [95% CI, 6.4 to 16.2]). Regression analyses demonstrated that compared with the GD-alone group, the risk for the composite end point was similar in the group with mild DGS+GD (DGS class 1, 2a) (hazard ratio, 1.15 [95% CI, 0.54 to 2.43]) while the group with severe DGS+GD (DGS class 2b, 3, 4) had a greater risk (hazard ratio, 3.60 [1.79 to 7.22]).

Conclusions
Among people with diabetes and GD, mild diabetic glomerular lesions on biopsy do not affect outcomes, but moderate-severe lesions increase the risk for ESKD and death. Whether use of immunosuppression, particularly glucocorticoids, is less successful in inducing GD remission in people with moderate-severe diabetic lesions will be a focus of future study in a larger population.
A Distinct Nasal Microbiota Signature in Peritoneal Dialysis Patients
Authors: Khan Iman , Wu Sylvia , Hudson Anika , Hughes Clayton , Stryjniak Gabriel , Westblade Lars F. , Satlin Michael J. , Tedrow Nicholas , Uhlemann Anne-Catrin , Kraft Colleen , Dadhania Darshana M. , Silberzweig Jeffrey , De Vlaminck Iwijn , Li Carol , Srivatana Vesh , Lee John Richard 
Published: August 2023

Key Points

Staphylococcus, Corynebacterium, Streptococcus, and Anaerococcus are the most common genera in the anterior nares.The nasal abundance of Staphylococcus is inversely correlated with the nasal abundance of Corynebacterium.Peritoneal dialysis patients have a distinctly diverse representation of Staphylococcus and Streptococcus in their anterior nares.

Background
The nasal passages harbor both commensal and pathogenic bacteria that can be associated with infectious complications. The nasal microbiome in peritoneal dialysis (PD) patients, however, has not been well characterized. In this study, we sought to characterize the anterior nasal microbiota in PD patients and assess its association with PD peritonitis.

Methods
In this study, we recruited 32 PD patients, 37 kidney transplant (KTx) recipients, and 22 living donor/healthy control (HC) participants and collected their anterior nasal swabs at a single point in time. We followed the PD patients for future development of peritonitis. We performed 16S ribosomal RNA (rRNA) gene sequencing of the V4–V5 hypervariable region to determine the nasal microbiota. We compared nasal abundance of common genera among the three groups using Wilcoxon rank-sum test with Benjamini–Hochberg adjustment. DESeq2 was also used to compare the groups at the amplicon sequence variant levels.

Results
In the entire cohort, the most abundant genera in the nasal microbiota included Staphylococcus, Corynebacterium, Streptococcus, and Anaerococcus. Correlational analyses revealed a significant inverse relationship between the nasal abundance of Staphylococcus and that of Corynebacterium. PD patients have a higher nasal abundance of Streptococcus than KTx recipients and HC participants. PD patients have a more diverse representation of Staphylococcus and Streptococcus than KTx recipients and HC participants. PD patients who concurrently have or who developed future Staphylococcus peritonitis had a numerically higher nasal abundance of Staphylococcus than PD patients who did not develop Staphylococcus peritonitis.

Conclusions
We find a distinct nasal microbiota signature in PD patients compared with KTx recipients and HC participants. Given the potential relationship between the nasal pathogenic bacteria and infectious complications, further studies are needed to define the nasal microbiota associated with these infectious complications and to conduct studies on the manipulation of the nasal microbiota to prevent such complications.
Структура розвитку голосової культури майбутнього вчителя
Authors: Перетяга Людмила 
Published: August 2023

У статті обґрунтовується сутність голосової культури майбутнього вчителя та структуру, яка представлена єдністю чотирьох взаємопов’язаних структурних блоків: професійно-педагогічного, технічного, гігієнічного, психологічного. Новизна дослідження полягає в цілісному виділенні функціональних компонентів, що забезпечують реалізацію структурних компонентів голосової культури, а їх виділення розкриває процесуальну сторону цього питання. Встановлено, що голосова культура має складну структуру, яка представлена єдністю чотирьох взаємопов’язаних блоків: професійно-педагогічного, технічного (забезпечення підготовки голосового апарату до підвищеного голосового навантаження),гігієнічного (підтримка голосового апарату у здоровому та працездатному стані), психологічного (спрямовання на досягнення взаєморозуміння з іншими суб’єктами педагогічного процесу шляхом урахування особливостей голосоутворення). Виділені структурні блоки представлені єдністю чотирьох універсальних для кожного структурного блоку компонентів: мотиваційно-аксіологічного, когнітивного, діяльнісно-практичного та рефлексивного. Виходячи зі специфіки діяльності вчителя та варіативності його взаємин, визначено основні функції: пізнавальна, гностична, ціннісно-орієнтаційна, прогностично-орієнтована, прогностично-профілактична, комунікативна, розвивально-виховна, енергетична, розподільна, захисна, рефлексивна. Доведено, що оволодіння вчителем культурою голосу дозволяє зменшити негативний вплив факторів професійної діяльності на стан голосового апарату вчителя та підтримувати стан голосового апарату в здоровому та працездатному стані. Сформульовано припущення, що розвиток вокальної культури допомагає досягти кращої взаємодії з оточуючими і з мінімальними наслідками для стану свого голосового апарату.
Aplikasi Mudah Alih bagi Pembelajaran Simpulan dan Ikatan Pengakap Muda
Authors: Jaffri Mohd Iqmal , Abdul Rahman Mohd Hishamuddin 
Published: August 2023

Kajian ini dilaksanakan untuk membina aplikasi mudah alih My Scouting Skill bagi sukatan pembelajaran Simpulan dan Ikatan Pengakap Muda dengan menggunakan model ADDIE dan seterusnya mengenalpasti kesahan dan kebolehgunaan aplikasi ini. Tahap kesahan dan kebolehgunaan aplikasi ini dilihat dari aspek penggunaan dan aplikasi yang disediakan. Kajian dijalankan ke atas 30 orang responden yang terdiri daripada Pemimpin Pelatih Pengakap dan nilai min yang diperolehi adalah melebih 3.00 iaitu diantara 3.01 - 4.00. Data diperolehi melalui kaedah kuantitatif untuk mendapatkan maklumat. Instrument kajian yang digunakan adalah borang soal selidik. Hasil kajian menunjukkan aplikasi My Scouting Skill mempunyai kesahan dan kebolehgunaan yang memuaskan. Kesimpulannya, persediaan alat bantu mengajar yang sesuai dapat menarik perhatian murid dalam pengajaran dan pembelajaran (PdP). Diharapkan dengan pembinaan aplikasi mudah alih ini membantu murid dan meningkatkan pemahaman murid dalam topik Simpulan dan Ikatan Pengakap Muda.

Building a Mobile Application for Learning of "Simpulan dan Ikatan Pengakap Muda"
Abstract: This study was implemented to build the My Scouting Skill mobile application for the Young Scout Knot and Bond learning syllabus by using the ADDIE model and further identify the validity and usability of this application. The level of validity and usability of this application is seen from the aspect of use and the application provided. The study was conducted on 30 respondents consisting of Scout Trainee Leaders and the mean value obtained was more than 3.00 which is between 3.01-4.00. Data were obtained through quantitative methods to obtain information. The research instrument used was a questionnaire. The results show that the My Scouting Skill application has satisfactory validity and usability. In conclusion, the preparation of appropriate teaching aids can attract students in teaching and learning (PdP). It is hoped that with the construction of this mobile application it helps the students and enhances the students understanding in the topic of Knots and Young Scout Bonds.
Keywords: ADDIE, Mobile Application, Teaching and Learning.
Memperkenalkan Tool Perisian Adobe Photoshops dalam Kalangan Pelajar Multimedia menggunakan Augmented Realiti
Authors: Intang Ezra , Ahmad Zaki Nadia Akma , Yani Achmad 
Published: August 2023

Aplikasi ini memperkenalkan tools perisian Adobe Photoshop dalam kalangan pelajar Multimedia, yang dibangunkan adalah bertujuan untuk membantu pelajar Multimedia untuk mengenali tools perisian Adobe Photoshop dengan cara yang lebih moden iaitu menggunakan AR. Reka bentuk aplikasi ini dibangunkan dengan menggunakan elemen multimedia seperti audio, video, grafik, animasi dan teks. Kajian ini dijalankan bagi mengetahui persepsi pengguna yang ianya merangkumi kebolehgunaan, keberkesanan dan reka bentuk responden terhadap hasil produk akhir yang telah dibangunkan. Pembangunan aplikasi ini dibangunkan menggunakan ADDIE Model. Dapatan kajian menunjukkan min yang terkumpul bagi responden kajian ialah 3.50 bagi persepsi kebolehgunaan, 3.33 bagi min persepsi keberkesanan dan 3.57 bagi persepsi reka bentuk aplikasi. Secara keseluruhannya, hasil kajian yang diperolehi oleh responden kajian menunjukkan skor min yang tinggi.

Appliying Augmented Reality to Introduce Adobe Photoshop Software Tools Among Secondary School Multimedia Students
Abstract: This application is introducing Adobe Photoshop software tools among multimedia students; it was developed to help multimedia students to recognize Adobe Photoshop software tools in a more modern way that is using AR. The design of this application is developed using multimedia elements such as audio, video, graphics, animation, and text. This study was conducted to find out consumer perceptions which include the usability, effectiveness, and design of respondents to the final product that has been developed. The development of this application was developed using the ADDIE Model. The findings of the study showed that the cumulative mean for the study respondents was 3.50 for the perception of usability, 3.33 for the mean of the perception of effectiveness, and 3.57 for the perception of application design. Overall, the results obtained by the study respondents showed a high mean score.
Keywords: ADDIE, Adobe Photoshop, Augmented Reality, Teaching and Learning Aids.
STUDY BAKING QUALITY OF SOME BREAD WHEAT GENOTYPES UNDER WATER STRESS
Authors: L. A. Hussain  , M. S. Hamdalla  , S. A. Yousif  
Published: August 2023

This study was aimed to investigate baking quality of some bread wheat and water stress. A field experiment was carried out at the fields of the College of Agricultural Engineering Sciences - University of Baghdad during the seasons 2018-2019 and 2019-2020. Five local cultivars and 20 entrance genotypes were planted, during first season and the best 9 genotypes for baking ability were selected and tested in the second season, under moisture depletion levels of 50, 70, and 90% of field capacity, RCBD was used for the first season, with a split-plot design for the second season, with three replications for both seasons. The levels of moisture depletion occupied the main plots and the genotypes of the sub plots. In the second season, the results showed that reducing the moisture depletion to the level of 50% of the available water produced the highest grain yield, while the 90% moisture depletion level exceeded 90% produced the highest means of the protein%. It could be concluded that the availability of the appropriate quantities of irrigation water reflected positively on grain yield and that the decrease in the quantities of irrigation water improved protein%.
THE USE OF TEST-DAY MILK YIELD AND LAMBS WEIGHT FOR PREDICTION OF SOME PRODUCTIVE TRAITS IN AWASSI SHEEP
Authors: Muthanna F. A. Al-Juwari  
Published: August 2023

This study was included 155 records of Awassi ewes and 199 records of lambs born during two seasons (2011-2012), belonging to the College of Agriculture and Forestry, Mosul University. The effect of year was highly significant on all traits except for weight gain from weaning to 180 days (GW180d). Age of dam was significantly affected daily milk yield (DMY), birth weight (BW), weaning weight (WW) and gain from birth to weaning (GBW). Type of birth had significant effect on DMY, BW,WW and weight at 180 days. The effect of lamb sex on WW, GBW was significant. Significant correlations coefficient were observed between DMY and total milk yield (TMY), months weight of lambs, GBW and GB180d being ranged from 0.46 to 0.99 and -0.44 to 0.99 respectively. The R2 values of prediction equations were high and ranged between 0.81 to 0.99 to predict TMY, and 0.97 to predict lamb weight at 180 days.
المضامين التعليمية الرئيسية بين شاهنامه الفردوسي والإلياذة والأوديسة لهوميروس – دراسة مقارنة
Authors: شاهوردي إلهام , وندي الأستاذ المساعد الدكتور مسعود 
Published: August 2023

تُعَدُّ الشاهنامه للفردوسي والإلياذة والأوديسة لهوميروس من أعظم روائع الأدب الفارسي والإغريقي . قد قامت بدراسة البعد الملحمي في الدراسة المقارنة لهذين الأثرين، وكان البعد التعليمي فيهما مغفولاً عند الباحثين لذلك كان من الضروري دراسة البعد التعليمي في الأثرين. ومن أهمّ اسباب التقارب بين الأمم هو الأدب المقارن وهو علم يبحث عن القواسم المشتركة واحتمالية التأثير والتأثير في إنتاجين أدبيين أو أكثر في شعبين مختلفين، بلغتين مختلفتين ثم يحللها تحليلاً تاماً. كانت لغة هوميروس في الإلياذة والأوديسا هي لغة التراث الأدبي والملحمي ولهذا يجب أن يستخدم لغة الشاهنامه الملحمية والكلمات الشائعة في الشعر الفارسي لقرب أكثر من المبدأ الإغريقي.
في هذا البحث، قمنا بدراسة العناصر التعليمية السباعية في الشاهنامه للفردوسي والإلياذة والأوديسة لهوميروس، وهي: تكريم الصديق وحفظ إحترامه، وكتمنان السرّ والمحبة والتقوى والمضياف والتجنب عن العار والتجنب عن الاستبداد. بعد الدراسة الوصفية ـ التحليلية، تشير النتائج إلى أن هذه المكونات التعليمية في ملحمة الشاهنامه واضحة وشفافة للغاية ولها تطور في الفكر. بينما أنّ هذه المؤلفات قليلة و غير واضحة في أعمال هوميروس ومن حيث التطور الفكري للإنسان، تكون في بداية المسار.
جماليات المطلق والمقيد في التصوير الاسلامي
Authors: الغزالي المدرس الدكتور حسن 
Published: August 2023

البحث بدراسة (جماليات المطلق والمقيد في التصوير الاسلامي ) واعتمد الباحث منهجية المباحث ، اذ خصص المبحث الاول منه لبيان مشكلة البحث ، والمبحث الثاني اهميته والحاجة اليه وهدف البحث وحدوده وتحديد اما المبحث الثالث فقد اهتم بالمصطلحات الواردة فيه .
تناولت مشكلة البحث موضوعة جماليات المطلق والمقيد في التصوير الاسلامي والذي انعكست في اعمال فناني المنمنمات الاسلامية بتمثيل الاشكال الفنية بحدود اللامتناهي والمحدود المقيد في صور المجتمع وعاداته في العصر الاسلامي حيث كان الفن قائم على التوثيق الصوري لفعاليات الروح الانسانية منذ بداية الحضارات القديمة ولهذا الوقت .
اما المبحث الخامس فقد اهتم بإجراءات البحث المتكونة من مجتمع البحث واختيار عينته البالغة ثلاث منمنمات فنية مثلت عينة البحث . وشمل المبحث الاخير على نتائج البحث ، واستنتاجاته واهم التوصيات والمقترحات . هذا ما جاء بالبحث اضافة الى المصادر المراجع العربية وملخص اللغة الانكليزية .
أثر القرآن الكريم في إنتقال الدلالة بسبب المجازالمرسل
Authors: علیخان الباحث جاسم 
Published: August 2023

موضوع هذا البحث من الموضوعات التي لها إرتباط وثيق بالقرآن الكريم ودراسة ظاهرة التطور في اللغة التي تبنها البعض في عصرنا الحاصر لرفع راية عدم القدرة للوصول إلى مقاصد صاحب النص التأريخي لبعد الزمن وحصول التغير والتطور في الأنسان والمجمتع، و ينتمي- هذا البحث- إلى الدراسات اللغوية والمباحث اللفظية في علم اللغة بشكل خاص وغيره من العلوم المرتبطة به التي جعلت اللغة والألفاظ محوراً لها؛ و يعالج الموضوع مسألة (المجاز المرسل) ودوره في التطور الدلالي من خلال تتبع الأمثلة لبعض الالفاظ في القرآن الكريم ويحاول الإجابة عن التساؤلات المطروحة حول مسألة البحث ويهدف البحث من وراء ذلك إستجلاء دور (المجاز المرسل) بإعتبارها مظهرا للتطور الدلالي في القرآن الكريم من جهة إنتقال الدلالة لبعض الألفاظ من دلالتها اللغوية إلى دلالة جديدة جاء بها القرآن الكريم.
وقد تم معالجة ذلك كله وفق منهج إستقرائي عقلي تحليلي، من خلال محاولة إستقراء بعض الألفاظ الواردة في آي الذكر الحكيم وآراء علماء اللغة والتفسير فيما يتعلق في هذا الحقل وما يقتضيه المنطق العلمي.
A new way of Presbyopia Treatment in Young People (20-40) years by Physical Exercises of the Eye Muscles.
Authors: Sameen Shuker Mundher 
Published: August 2023

Examination of degree of vision for patient to determine presbyopia in young people before and after therapeutic exercises and to know the amount of improvement in each session after taking a history of the patient and identification of treatment methods according the prescription with the eye moving to all directions and push it forward to reduce pressure on the eye muscle about 20 mints during the exercises (1-6) session in order to stimulate the weak eye.
The appearance of presbyopia among young people from new cases because concentration for long periods and for more than 4 hours using the modern devices, which caused the occurrence phenomenon among young people and need for reading glasses. All patients were treated of and improved in the degree of consideration each session with therapeutic exercises after identifying and moving the weak eye muscle and found the examination and do not need to use any glasses to read during the examination and get visual acuity (VA=6/6 or 6/9).
Identification study for suspected women with Trichomonas vaginalis by PCR technique in AL-Najaf AL-Ashraf province
Authors: Khteer Al-Hadraawy Saleem , R. Al-Katib Sami , M. H. Al-Awady Haithem 
Published: August 2023

The study was conducted on 450 out patients and 30 healthy women, whom have visited the department of infertility at Al-Sadder medical city and Al-Zahra Hospital in Najaf Province during the period from January till August, 2012. The infection with T.vaginalis in clinical suspected women determine by using PCR technique, the infection women numbers and percent by PCR test gave 58 and 12.88% respectively. DNA of T.vaginalis parasite was determined by PCR was using five specific primers (BTUB 9/2, BGL 1/2, TVA 5/6, TV 1/2 and OP 1/2) whereas the number, percent and sensitivity of infected women of these primers were 58 (12.88%) (100%), 56 (12.44%) (96.55%), 53 (11.77%) (91.37%) and 52 (11.55%) (89.65%) respectively, from comparing between these primers to evaluate the efficiency in diagnostic of T.vaginalis .Indicated that BTUB 9/2, BGL 1/2 the highest primers and OP 1/2 the lowest primers in diagnostic efficiency.