bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gaussian mixture model based radio environment mapping for an underlay Device‐to‐Device network
Authors: Sengar Aditya Singh , Gangopadhyay Ranjan , Debnath Soumitra 
Published: March 2023

AbstractEfficient management of the scant radio resources in densely deployed Device‐to‐Device (D2D) and IoT networks in 5G+ and 6G wireless era would require continuous and reliable information feedback regarding the actual on‐ground resource utilization. Toward that goal, radio environment maps (REM) are becoming increasingly important as they provide critical information relevant for network management. REM essentially entails the estimation of the radio environment at unsampled locations using the values measured by a few dedicated REM sensors by interpolation. Hence, the accuracy of REM is dependent upon two major factors (1) the sensor deployment and (2) the interpolation scheme. So far, the ordinary Kriging (OK) with randomly deployed sensors is the most prevalent method of REM creation. However, the underlying assumption in OK is that the radio environment conforms to a Gaussian spatial random field (GSRF). In reality, the spatial random field generated by a D2D network displays non‐Gaussian characteristics. Hence, a variational Bayesian based Gaussian mixture model enabled Kriging (VK) method has been proposed in this work which achieves better interpolation accuracy than OK with a lower run‐time computational complexity. A comparison of various sensor deployment schemes on the basis of REM accuracy in fading channel conditions has also been conducted. Additionally, a spatial‐correlation based method has been proposed to estimate the minimum number of required REM sensors to ensure reliable REM performance. The simulation results indicate a superiority of hexagonal deployment of sensors over other schemes and establish VK as a more accurate interpolation algorithm than OK.
Young children's use of blue spaces and the impact on their health, development and environmental awareness: A qualitative study from parents' perspectives
Authors: George Phoebe , Murray Kevin , Christian Hayley 
Published: March 2023

AbstractIssue AddressedThis study examined how families with young children access and use different types of blue spaces and the health and development benefits, and potential negative effects.MethodsParents(n = 25) of young children across four coastal communities in Western Australia were recruited via purposive sampling to participate in interviews. A generic qualitative study design grounded in the pragmatism paradigm was utilised.ResultsBeaches were the most frequently used blue space for families all year around, however families did not necessarily attend their closest beach. This appears due to certain beach features making them more or less attractive for use regardless of the distance from home. Parents perceived blue spaces as health promoting due to the increased physical activity children did in and around these spaces. They also reported blue spaces could be positive for child development, contributing to the development of identity. Blue spaces were also perceived to promote children's environmental awareness and environmentally friendly behaviours. However, blue spaces could also be potentially risky environments for families with young children.ConclusionsThe findings highlight blue spaces are an important setting for supporting children's health, development and environmental consciousness.So What?It is important to protect natural outdoor environments such as blue spaces for future generations. The findings can be used by governments and policy makers to improve the quality (features and amenities) of blue spaces and positively impact how often families (including those with dogs) use blue spaces and the benefits they experience.
Characteristics and treatment analysis of young acute coronary syndrome patients in a tertiary care hospital: A cross‐sectional retrospective study
Authors: Murugan Jagannaathan , Balasubramaniyan Jayanty Venkata , Mathiyalagan Praveen Kumar , Ramesh Yashwanth , Selvam Meera , Charley Chris , Muralidharan Harini , Venati Rishitha , Dhanasekaran Indrani Devi , Rajanandh Muhasarparur Ganesan 
Published: March 2023

AbstractBackground and AimsThe prevalence of acute coronary syndrome (ACS) has been rising in the younger population worldwide. To fully comprehend the effects of the condition, it is crucial to examine the evolving characteristics and treatment options. The purpose of this study is to evaluate the characteristics and treatment analysis for young ACS patients in a tertiary care setting.MethodsThis cross‐sectional, retrospective, single‐center study included a random sample of patients who had been hospitalized for ACS over the period of a year. We collected and analyzed data on risk factors, diagnoses, angiographic patterns, and potential treatments.ResultsThe study involved 198 young ACS patients in total. The majority of patients (57%) had no risk factors, and the majority of them (44%) had ST‐elevation myocardial infarction (STEMI) as their diagnosis. The most common type (48%) was single‐vessel disease (SVD). Statins and antiplatelet medications made up the majority of the patients’ nonsurgical treatments (88% and 87%, respectively). A statistically significant difference exists between young and older ACS patients with gender (p < 0.01). However, it is not clinically relevant.ConclusionMen were the majority of young ACS patients, and STEMI, SVD were more prevalent. The majority of young ACS patients had no significant risk factors. To determine the risk factors of young ACS patients, a more thorough case–control study is critically needed.
Experimental study for comparison of thermal comfort and air age between two combined ventilation systems with chilled ceiling considering occupant density
Authors: Nayyef Dhuha Radhi , Mahdi Ala'a Abbas 
Published: March 2023

AbstractDue to the global spread of diseases and epidemics, the need to maintain a clean indoor atmosphere has received increasing attention in recent years. Therefore, there will be a need to clearly estimate and define the areas that affect human exposure to pollutants, taking into account the occupied density, which is the primary importance of this research. The capacity of the chilled ceiling combined with mixing ventilation and personal ventilation systems has been studied and compared to the chilled ceiling with mixing ventilation in terms of mean air age, temperature distribution, CO2concentration, and thermal efficiency, with the best flow rate of the proposed system considering the occupied density in a thermally insulated office room experimentally in the climate of Iraq (Hilla, a hot and dry climate). Twelve tests were performed for four different cooling loads with cooled ceilings (0%, 0.25%, 50%, and 80%), at a constant supply air flow rate with two PV airflow modifiers for three cases. As the cooling load treated by a chilled ceiling increased, the average air temperature increased with height in all cases. The lowest values of average air age appeared in the occupied area in the case of a chilled ceiling with mixing ventilation. This study shows that the chilled ceiling combined with a mixing ventilation and personal ventilation system with a flow rate of 7.5 L/s provides thermal comfort and higher air quality in the occupied area. based on the values of air exchange efficiency and occupants’ air exchange efficiency. As a result, a flow rate of 7.5 L/s is the best option for protecting occupants from direct pollution in the breathing zone and in the surrounding microclimate, because the lower the ventilation rate, the less air is changed for occupants.
超音波検査が診断に有用であった心嚢気腫による心タンポナーデの1例(Ultrasonographic diagnosis of cardiac tamponade due to pneumopericardium: a case report)
Authors: 広登 坂本 , 憲市 新田 , 保瑛 前田 , 雄二朗 濱野 , 通太郎 市川 , 勝徳 望月 , 浩 今村 
Published: March 2023

要旨　鋭的胸部外傷に伴う心嚢気腫は稀であるが，閉塞性ショックを生じうる緊急性の高い病態である。症例は80歳の男性。自殺企図による頸部刺創，胸部刺創でドクターヘリが要請された。病院前医療で気管損傷，左開放性血気胸に対して，気管挿管，刺創部の3点テーピング，左胸腔ドレナージを施行し当院へ搬送となった。来院後に血圧が低下し超音波検査で心嚢気腫による心タンポナーデを来していると考え，刺創部より用指的に緊急脱気を行い，速やかに血圧の上昇を得た。同日に永久気管孔を作成した。その後，心電図上ST上昇が見られたが，心筋逸脱酵素の上昇はなく冠動脈造影では冠動脈損傷などの所見はなかった。第12病日に胸腔ドレーンを抜去し，第21病日に耳鼻咽喉科へ転科し，第39病日に独歩で自宅退院した。本症例では，鋭的胸部外傷で来院後，超音波検査で心嚢気腫を疑い，心タンポナーデを来したが速やかに用指的に解除できたことが救命につながったと考えられる。
神経学的後遺症を残した電撃型脂肪塞栓症候群の1例～文献レビューと予後調査～(A case of fulminant fat embolism syndrome with neurological deficit: literature review and prognosis research)
Authors: 雄一 齋坂 , 龍一郎 奥田 , 泰明 山川 , 比呂人 伊與田 , 浩平 宮下 , 篤史 盛實 , 朋子 杉村 
Published: March 2023

要旨電撃型脂肪塞栓症候群（電撃型FES）は外傷後短時間で発症し，致死的転帰をたどり生命予後も不良と報告されているがまとまった報告はない。神経学的後遺症を残した電撃型FESの1例を生命予後・神経学的予後を調査した文献レビューとともに報告する。症例は18歳の男性。交通事故により受傷し，救出後に当院救急搬送となった。来院時ショックはなく，意識レベルはGCS E3V4M6で軽度の不穏を認めた。顔面挫滅創を認めたがCTで頭蓋内損傷はなく，右肘開放性脱臼骨折および右大腿骨骨幹部骨折を認めた。受傷後8時間で骨折に対する緊急手術を行った。術中より血圧低下あり，術後に低酸素状態・意識レベル不良であり，再挿管・人工呼吸器管理となった。直後に行ったCTで肺野のすりガラス影の出現と脳浮腫を認め，翌日には点状出血の出現を認めたため電撃型FESの診断となった。集学的治療を行ったが，けいれんの出現があり，受傷後22日に撮像した頭部MRIでは多発性の陳旧性脳梗塞像を認めた。受傷後35日の転院時E3VTM3と意思疎通は困難であった。受傷後1年の時点で追視は可能だが意思疎通困難で，随意的な四肢運動は不可能である。文献レビューでは電撃型FESは日本語文献26例，英語文献14例の症例報告があり，死亡率は43～50%で，神経学的後遺症発生率は43～56%であった。
In vitro and in vivo suppression of SARS‐CoV‐2 replication by a modified, short, cell‐penetrating peptide targeting the C‐terminal domain of the viral spike protein
Authors: Kim Dongbum , Kim Jinsoo , An Seungchan , Kim Minyoung , Baek Kyeongbin , Kang Bo Min , Maharjan Sony , Kim Suyeon , Hwang Seok Young , Park In Guk , Park Sangkyu , Suh Jun Gyo , Park Man‐Seong , Noh Minsoo , Lee Younghee , Kwon Hyung‐Joo 
Published: March 2023

AbstractPeptides are promising therapeutic agents for COVID‐19 because of their specificity, easy synthesis, and ability to be fine‐tuned. We previously demonstrated that a cell‐permeable peptide corresponding to the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Spike C‐terminal domain (CD) inhibits the interaction between viral spike and nucleocapsid proteins that results in SARS‐CoV‐2 replication in vitro. Here, we used docking studies to design R‐t‐Spike CD(D), a more potent short cell‐penetrating peptide composed of all D‐form amino acids and evaluated its inhibitory effect against the replication of SARS‐CoV‐2 S clade and other variants. R‐t‐Spike CD(D) was internalized into Vero cells and Calu‐3 cells and suppressed the replication of SARS‐CoV‐2 S clade, delta variant, and omicron variant with higher potency than the original peptide. In hemizygous K18‐hACE2 mice, intratracheal administration of R‐t‐Spike CD(D) effectively delivered the peptide to the trachea and lungs, whereas intranasal administration delivered the peptide mostly to the upper respiratory system and stomach, and a small amount to the lungs. Administration by either route reduced viral loads in mouse lungs and turbinates. Furthermore, intranasally administered R‐t‐Spike CD(D) mitigated pathological change in the lungs and increased the survival of mice after infection with the SARS‐CoV‐2 S clade or delta variant. Our data suggest that R‐t‐Spike CD(D) has potential as a therapeutic agent against SARS‐CoV‐2 infection.
Excess acute diarrhoea cases attributed to norovirus variants in Beijing, China between 2011 and 2018
Authors: Liu Baiwei , Wang Yu , Wang Xiaoli , Jia Lei , Tian Yi , Yan Hanqiu , Li Weihong , Shen Lingyu , Wang Quanyi , Gao Zhiyong 
Published: March 2023

AbstractNew norovirus (NoV) variants emerge often leading to increased acute gastroenteritis outbreaks and outpatient visits. However, these increases are rarely quantified. Between September 2011 and August 2018, we included a total of 133 131 acute diarrhoea cases in 11 enteric disease outpatient clinics which were open all year round in Beijing. Over the same period, the etiology surveillance for acute diarrhoea was conducted, a total of 13 139 specimens were collected and tested, and 16.84% (2213/13 139) of all specimens were NoV‐positive. The partial VP1 genes were successfully sequenced in 965 NoV strains. GII.4 Sydney, GII.17, and GII.2 predominated in 2012–2013, 2014–2015, and 2016–2017, respectively. We estimated the excess NoV‐associated acute diarrhoea cases using the adjusted Serfling regression model, and three excess periods were found, corresponding to the predominance periods of GII.4 Sydney, GII.17 and GII.2, respectively, represented increases of 180.5% (95% confidence interval [CI]: 115.0%–246.0%), 114.7% (95% CI: 66.4%–163.1%) and 152.6% (95% CI: 100.2%–205.0%), compared with the baseline level. New NoV variants often caused an excess in their first year of predominance, and the excess periods of NoV‐associated acute diarrhoea cases coincided with the predominance periods of NoV variants.
Impact of drought conditions on air pollution over Turkey
Authors: Baltaci Hakki , Tumay Gozde , Labban Abdulhaleem H. 
Published: March 2023

AbstractAs a natural disaster, drought affects many sectors such as agriculture and hydrology, as well as having an effect on air quality. In terms of air pollution, drought can reduce wet scavenging of pollutants and change their chemical production/loss and lifetime. This study investigates the relationship between drought events and air pollutants in Turkey. As a drought indicator, the Standardized Precipitation‐Evapotranspiration Index (SPEI)‐1 monthly values for dry (SPEI < −0.99), normal (−0.99 < SPEI < 0.99) and wet (SPEI < 0.99) conditions were used to investigate the changes in PM10, PM2.5, O3 concentration levels. Monthly mean PM10 values of 80 stations for the period 2010–2018, PM2.5 and O3 values of 10 and 12 stations, respectively, were used for the analysis throughout the 2014–2018 period. According to the results, while frequency occurrence of normal conditions decreased in the last period (2010–2018) when compared to the first (1901–2009), drought conditions have significantly increased in each region of Turkey in the last decade. Highest increase in drought events occurred in the inner/southern parts of Turkey. In dry events, while PM10 levels of the stations show above‐normal values, highest regional increase in PM10 was found in the Central Anatolia (CAR), Mediterranean (MeR), Aegean (AR) and Marmara (MR) regions of the country. In fall, high daily temperatures and cloudless days in CAR and MeR regions are seen under deep surface low over continental Europe and surface high over Caspian Sea, which result in severe dryness events and associated high PM10 values in the air quality stations. On the other hand, as a consequence of the expanding Asiatic monsoon low to the eastern part of Turkey, significant amount of moisture is transferred from the Eastern Mediterranean Sea surface to the CAR and MeR regions by southerly flows (wetness SPEI conditions in fall) and cause to appear below‐normal PM10 values in the southern stations.
The Role of Substance P Receptor Antagonists in Allergic Rhinitis: Ovalbumin‐Induced Rat Model
Authors: Becerik Çağrı , Karaca Çiğdem T. , Özcan Zühal , Kul Selim , Toros Sema Z. 
Published: March 2023

ObjectiveSubstance P is a peptide from the tachykinin family, which is found in peripheral and central nervous systems, causing vasodilation and increased secretion in the nasal mucosa. In this study, we aimed to investigate whether the experimental model of allergic rhinitis will cause allergic changes in the larynx and to compare the effects of aprepitant, a substance P antagonist, on nasal symptoms in allergic rhinitis, and histopathological changes in the nasal and laryngeal mucosa with antihistamine and leukotriene receptor antagonists (LTRA).Study DesignAn experimental animal study.MethodThe study was carried out on 34 healthy 8–12 weeks old female Sprague Dawley rats in 5 groups. The rats in which an experimental allergic rhinitis model was created with ovalbumin were scored by observing their nasal symptoms, and nasal and laryngeal mucous membranes included in the study were evaluated histopathologically after medications.ResultsAs a result of the analysis of the data obtained from the study, antihistamine and LTRA significantly reduced the symptoms of nose scratching and sneezing, while aprepitant did not affect nasal symptoms. In the histopathological examination of the larynx, effects that would make a significant difference were found in the allergy group when compared to the control group. On the larynx, aprepitant reduced pseudostratification significantly compared to the allergy group.ConclusionAprepitant provides histopathological changes in the treatment of allergic rhinitis, but does not have sufficient effect on nasal symptoms. The effect of aprepitant on the larynx has not been clearly demonstrated.Level of EvidenceNA Laryngoscope, 133:2891–2897, 2023
Men engage in self‐deceptive enhancement, whereas women engage in impression management
Authors: Lalwani Ashok K. , Lee Hyejin , Shrum L. J. , Viswanathan Madhu 
Published: March 2023

AbstractConsumer surveys are integral to marketers' understanding of consumers' judgments, preferences, and choices. However, consumers often respond in socially desirable ways, making it difficult to accurately ascertain their true preferences and reactions. In this regard, research has produced conflicting findings on who engages more in socially desirable responding: men or women. Our research is at the intersection of psychology and marketing to understand the effect of gender differences on socially desirable responding. We tested hypotheses regarding the types of socially desirable responding of men versus women and the underlying motivations. Across three studies, we show that men (compared to women) have a greater tendency to engage in self‐deceptive enhancement—the tendency to provide inflated and honestly held self‐descriptions in response to questions—and a promotion focus mediates this relationship. In contrast, women (compared to men) have a greater tendency to engage in impression management—the tendency to distort responses to present themselves most positively to maintain a favorable image—and a prevention focus mediates this relationship. Consequently, gender differences in promotion versus prevention focus are likely to have important theoretical implications for a gender‐based explanation of different behaviors associated with regulatory focus. From a practical standpoint, marketers can utilize priming techniques to temporarily heighten gender identity and influence preferences for products that provide self‐enhancement or image‐protection benefits.
Carbazolic Conjugated Microporous Polymers for Photocatalytic Organic Transformations
Authors: Zhang Weijie , Shu Caihua , Cui Haishuai , Wan Quan , Au Chak‐Tong , Yi Bing , Yang Hai 
Published: March 2023

AbstractHeterogeneous photocatalysis have been deemed as a versatile and colorful platform for exploring efficient transformation systems. Henceforth, the design of photocatalysts underpins a wide range of research interests. By virtue of synthetic versatility, stability, non‐toxicity, purely organic properties, tunable semiconductive structures, and remarkable visible‐light absorbance, conjugated microporous polymers (CMPs) have emerged as an attractive new class of semiconductor materials that show great potential for tackling important energy and environmental challenges. Over the past decade, immense efforts have been devoted toward the construction of CMPs‐based photocatalysts for versatile photocatalytic transformations. This review aims to summarize the latest representative advances in the field of carbazolic CMPs, focusing on various design strategies for the construction of tailor‐made skeletons that have direct impact on their charge dynamics and thus photocatalytic performances, especially on their specific photocatalytic efficiency for organic transformations. Scrutinizing the photocatalytic features and elucidating the related design principles, it is fully described how structure modification of polycarbazoles could have an effect on optical properties, and thus on photocatalytic performance. Furthermore, the bottlenecks that need to be addressed, and the future research directions of CMPs are identified in the area of photocatalysis.
The Effect of Inulin‐Type Fructans on Plasma Trimethylamine N‐Oxide Levels in Peritoneal Dialysis Patients: A Randomized Crossover Trial
Authors: Xiong Qianqian , Li Li , Xiao Yonghua , He Shuiqing , Zhao Jing , Lin Xuechun , He Yuqin , Wang Jinxue , Guo Xiaolei , Liang Wangqun , Zuo Xuezhi , Ying Chenjiang 
Published: March 2023

ScopeTrimethylamine N‐oxide (TMAO), an important proatherogenic uremic toxin, is oxidized by hepatic‐flavin monooxygenases from gut microbiome‐generated trimethylamine (TMA). The present study aims to explore whether manipulating the gut microbiota by inulin‐type fructans (ITFs) can reduce circulating TMAO levels in peritoneal dialysis patients.Methods and resultsThis is a randomized, double‐blind, placebo‐controlled, crossover trial with 10 g day−1 ITFs intervention for 3 months in continuous ambulatory peritoneal dialysis patients. The gut microbiome is measured, and TMA‐producing gene clusters are annotated using shotgun metagenomic sequencing. Fecal and plasma TMA, plasma TMAO, and daily urine excretion and dialysis removal of TMAO are measured. Finally, 22 participants complete the trial. The daily intake of macronutrients and TMAO precursors is comparable during the prebiotics, washout, and placebo interventions. The ITFs intervention increases the Firmicutes/Bacteroidetes (F/B) ratio (p = 0.049) of gut microbiome. However, no significant influences are observed on fecal TMA content, circulating TMAO levels, or TMA‐producing gene clusters, including choline TMA‐lyase (CutC/D), carnitine monooxygenase (CntA/B), and betaine reductase (GrdH).ConclusionsIntervention with 10 g day−1 of ITFs for 3 months is not sufficient to reduce plasma TMAO levels in peritoneal dialysis patients, but it improves the gut microbiome composition.
Technical note: Measurement of the bunch structure of a clinical proton beam using a SiPM coupled to a plastic scintillator with an optical fiber
Authors: García Díez Miguel , Espinosa Rodriguez Andrea , Sánchez Tembleque Victor , Sánchez Parcerisa Daniel , Valladolid Onecha Victor , Vera Sanchez Juan A. , Mazal Alejandro , Fraile Luis Mario , Udias Jose Manuel 
Published: March 2023

AbstractBackgroundRecent proposals of high dose rate plans in protontherapy as well as very short proton bunches may pose problems to current beam monitor systems. There is an increasing demand for real‐time proton beam monitoring with high temporal resolution, extended dynamic range and radiation hardness. Plastic scintillators coupled to optical fiber sensors have great potential in this context to become a practical solution towards clinical implementation.PurposeIn this work, we evaluate the capabilities of a very compact fast plastic scintillator with an optical fiber readout by a SiPM and electronics sensor which has been used to provide information on the time structure at the nanosecond level of a clinical proton beam.Materials and methodsA 3 × 3 × 3 mm3 plastic scintillator (EJ‐232Q Eljen Technology) coupled to a 3 × 3 mm2 SiPM (MicroFJ‐SMA‐30035, Onsemi) has been characterized with a 70 MeV clinical proton beam accelerated in a Proteus One synchrocyclotron. The signal was read out by a high sampling rate oscilloscope (5 GS/s). By exposing the sensor directly to the proton beam, the time beam profile of individual spots was recorded.ResultsMeasurements of detector signal have been obtained with a time sampling period of 0.8 ns. Proton bunch period (16 ns), spot (10 μs) and interspot (1 ms) time structures could be observed in the time profile of the detector signal amplitude. From this, the RF frequency of the accelerator has been extracted, which is found to be 64 MHz.ConclusionsThe proposed system was able to measure the fine time structure of a clinical proton accelerator online and with ns time resolution.