bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional descriptions increase accidental harm punishment and its cortico-limbic signatures during moral judgment in autism
Authors: Fittipaldi Sol , Armony Jorge L. , García Adolfo M. , Migeot Joaquín , Cadaveira Matías , Ibáñez Agustín , Baez Sandra 
Published: January 2023

AbstractIndividuals with autism spectrum disorder (ASD) present difficulties in integrating mental state information in complex moral tasks. Yet, ASD research has not examined whether this process is influenced by emotions, let alone while capturing its neural bases. We investigated how language-induced emotions modulate intent-based moral judgment in ASD. In a fMRI task, 30 adults with ASD and 27 neurotypical controls read vignettes whose protagonists commit harm either accidentally or intentionally, and then decided how much punishment the protagonist deserved. Emotional content was manipulated across scenarios through the use of graphic language (designed to trigger arousing negative responses) vs. plain (just-the-facts, emotionless) language. Off-line functional connectivity correlates of task performance were also analyzed. In ASD, emotional (graphic) descriptions amplified punishment ratings of accidental harms, associated with increased activity in fronto-temporo-limbic, precentral, and postcentral/supramarginal regions (critical for emotional and empathic processes), and reduced connectivity among the orbitofrontal cortex and the angular gyrus (involved in mentalizing). Language manipulation did not influence intentional harm processing in ASD. In conclusion, in arousing and ambiguous social situations that lack intentionality clues (i.e. graphic accidental harm scenarios), individuals with ASD would misuse their emotional responses as the main source of information to guide their moral decisions. Conversely, in face of explicit harmful intentions, they would be able to compensate their socioemotional alterations and assign punishment through non-emotional pathways. Despite limitations, such as the small sample size and low ecological validity of the task, results of the present study proved reliable and have relevant theoretical and translational implications.
An experimental study of magnetic compression technique for ureterovesical anastomosis in rabbits
Authors: An Yingfeng , Zhang Miaomiao , Xu Shuqin , Deng Bo , Shi Aihua , Lyu Yi , Yan Xiaopeng 
Published: January 2023

AbstractThis study aimed to explore the feasibility of the magnetic compression technique (MCT) for ureterovesical anastomosis in a rabbit model with ureteral obstruction. The distal ureteral obstruction model using female New Zealand rabbits was induced by ligating the distal end of the right ureter with silk thread for four weeks. A pair of cylindrical NdFeB magnets (daughter magnet and parent magnet) with a hole in the center was used for the ureterovesical anastomosis. The daughter magnet and the parent magnet were respectively placed close to the obstruction site through the dilated proximal ureter and urethra, and then the daughter-parent magnets pair was attracted together automatically. Postoperative X-rays were taken to confirm the position of the magnets. The anastomotic stoma specimens were obtained two weeks postoperatively, and the anastomotic stoma formation was observed by the naked eye and histological staining. The operation time and the anastomotic burst pressure were measured. The ureter was significantly dilated in the fourth week after ligation, which satisfied the placement of the daughter magnet. The ureterovesical magnet placements were successfully performed in ten experimental rabbits, with an operation time of 36.5 ± 6.09 min. The parent and daughter magnets attracted each other well and were subsequently removed through the urethra two weeks postoperatively, resulting in the establishment of ureterovesical anastomosis. The anastomotic burst pressure was 147.5 ± 14.59 mmHg. Gross specimens and histological examination of the anastomotic stoma showed that the anastomotic stoma healed well. MCT is feasible and simple for ureterovesical anastomosis.
Analysis of vocal communication in the genus Falco
Authors: Griffiths Carole S. , Aaronson Neil L. 
Published: February 2023

AbstractVocal learning occurs in three clades of birds: hummingbirds, parrots, and songbirds. Examining vocal communication within the Falconiformes (sister taxon to the parrot/songbird clade) may offer information in understanding the evolution of vocal learning. Falcons are considered non-vocal learners and variation in vocalization may only be the result of variation in anatomical structure, with size as the major factor. We measured syringes in seven Falco species in the collection at the American Museum of Natural History and compiled data on weight, wing length, and tail length. Audio recordings were downloaded from several libraries and the peak frequency and frequency slope per harmonic number, number of notes in each syllable, number of notes per second, duration of each note, and inter-note duration was measured. Mass, wing length, and syringeal measurements were strongly, positively correlated, and maximum frequency is strongly, negatively correlated with the size. Frequency slope also correlates with size, although not as strongly. Both note and inter-note length vary significantly among the seven species, and this variation is not correlated with size. Maximum frequency and frequency slope can be used to identify species, with the possibility that bird sounds could be used to identify species in the field in real time.
New failure mechanism for evaluating seismic and static undrained bearing capacity adjacent to 2D slope
Authors: Fang Hongwei , Xu Yixiang 
Published: January 2023

AbstractThe seismic or static undrained slip line field theory and Cauchy, Riemann, mixed boundary value problems for undrained soil slopes are derived. A new failure mechanism is proposed to determine the undrained bearing capacity adjacent to slopes. The effects of geometric or strength parameters and seismic forces on static and seismic undrained bearing capacity are investigated. The convergence of the proposed method is proved. The static and seismic undrained bearing capacities predicted by the proposed method are close to those of the currently existing methods. The proposed method does not need to assume or search the failure modes, and a new limit state evaluation index is given.
Detecting geographical clusters of low birth weight and/or preterm birth in Japan
Authors: Rahman Md. Obaidur , Yoneoka Daisuke , Murano Yayoi , Yorifuji Takashi , Shoji Hiromichi , Gilmour Stuart , Yamamoto Yoshiko , Ota Erika 
Published: January 2023

AbstractIn Japan, mean birth weight has significantly decreased from 3152 g in 1979 to 3018 g in 2010 and the prevalence of preterm birth (PTB) has risen to 5.7% in the last thirty years. However, the presence and magnitude of geographical differences in low birthweight (LBW) and/or PTB in Japan is not well understood. We implemented spatial analysis to identify localized clusters and hot spots of LBW and/or PTB during 2012–2016. The Japan national birth database was used in this study. A total of 5,041,685 (male: 2,587,415, female: 2,454,270) births were used for spatial analysis using empirical Bayes estimates of the incidence rate of LBW and/or PTB and spatial scan tests to detect hot-spot areas with p values calculated from Monte Carlo iterations. The most and second likely clusters were located in two areas: (1) the small islands in south-west Japan (Amami and Okinawa, Relative risk = 1.09–1.67 with p < 0.001) and (2) the cities on the base of Mt. Fuji, stretching over three neighboring prefectures of Yamanashi, Shizuoka and Kanagawa (Relative risk = 1.10–1.55 with p < 0.001), respectively. We need to optimize the medical resource allocations based on the evidence in geographical clustering of LBW and/or PTB at specific locations in Japan.
Carcinogenicity and testicular toxicity of 2-bromopropane in a 26-week inhalation study using the rasH2 mouse model
Authors: Goto Yuko , Saito Arata , Takanobu Kenji , Senoh Hideki , Saito Misae , Umeda Yumi , Yamano Shotaro 
Published: January 2023

Abstract2-Bromopropane (2-BP) is a colorless liquid at room temperature and is used in closed systems in factories, mainly as an intermediate for medicines, pesticides, and other chemicals. However, the carcinogenicity of 2-BP is still unknown. The CByB6F1-Tg(HRAS)2Jic (rasH2) transgenic mouse model has been established as an alternative to long-term studies (1.5 years—lifetime) to detect carcinogenicity in as short a time as six months. We performed a 26-week inhalation exposure study of 2-BP using the rasH2 mouse model. Male and female rasH2 mice were exposed to 0, 67, 200, or 600 ppm of 2-BP for 6 h/day, 5 days/week for 26 weeks. All tissues and blood were collected and subjected to biological and histopathological analyses. The results showed a concentration-dependent increase in lung tumor development in male and female rasH2 mice exposed by inhalation to 2-BP, which was significant by Peto’s and Poly-3 trend tests. Furthermore, in male rasH2 mice, 2-BP was found to be a testicular toxin. This study is the first to demonstrate that 2-BP is carcinogenic in male and female mice and a testicular toxin in male mice using the rasH2 mouse model.
Handgrip strength in older adults from Antioquia-Colombia and comparison of cutoff points for dynapenia
Authors: Patiño-Villada Fredy Alonso , Estrada-Restrepo Alejandro , Aristizábal Juan 
Published: January 2023

AbstractHandgrip strength is a predictor of functional impairment and presence of morbimortality in older adults. However, appropriate reference values and cutoff points are required for its optimal use. This study describes handgrip characteristics in the older adult population of Antioquia-Colombia and compares the dynapenia handgrip cutoffs proposed for Colombians with international criteria. A cross-sectional study including 1592 older adults was done. Dynapenia prevalence by handgrip was analyzed using the following cutoffs: European Consensus of Sarcopenia (2018), Asian Working Group for Sarcopenia (2019), Chilean (2018), and Colombian (2019). Handgrip strength significantly decreased with aging, showing a positive and strong association with functional and health parameters. The highest prevalence of dynapenia was found with the Asian Consensus cutoffs (26.1%) and the lowest with the Colombian cutoffs (0.8%). Low agreement was found between the Colombian cutoffs with the European Consensus (kappa = 0.059; p < 0.001), the Asian Consensus (kappa = 0.039; p < 0.001) and the Chilean proposal (kappa = 0.053; p < 0.001). Dynapenia using the Chilean, European, and Asian cutoffs was associated with physical inactivity, presence of multimorbidity, slow gait speed, nutritional risk, and low calf circumference. Meanwhile, the Colombian cutoffs was only associated with slow gait speed and low calf circumference. The handgrip cutoffs proposed for Colombians seems to underestimate the dynapenia prevalence in older people from Antioquia. Furthermore, these cutoff points did not show associations with relevant functional and health parameters. The handgrip cutoffs proposed for Colombians should be used with caution.
The designing and modeling of equal base circle herringbone curved bevel gears
Authors: Zhang Ruiping , Zhang Bo , Fu Shixiang 
Published: January 2023

AbstractBased on the theory of equal base circle bevel gears, a new type of gear, the equal base circle herringbone curved bevel gear, is studied further to reduce the axial force problem of curved bevel gears. Using the principle of equal basis circle herringbone curved bevel gear as a basis, the tooth trace and the tool design of this gear were studied. Based on the principle of space meshing, the process of finger milling cutter enveloping machining gear was analyzed, and a tooth surface equation was calculated; This paper proposes two modeling methods: tooth trace modeling and tooth surface modeling. The gear model is consistent through the analysis and comparison of the two modeling methods. The axial force of the gear contact between the equal base circle herringbone curved bevel gear and Gleason are analyzed and compared, which verified the proper reduction of axial force.
Early warm compress treatment can promote recanalization of vascular embolisms and reduce tissue necrosis after polymethyl methacrylate injection
Authors: Sun Yimou , Jin Mengying , Wang Guanhuier , Xie Hongbin 
Published: February 2023

AbstractInjection of fillers for soft tissue augmentation can lead to a variety of complications, among which vascular occlusion caused by intravascular injection of filler will induce severe or permanent damage. The treatment strategies for intravascular embolization caused by injection include warm compress application, but the exact beneficial effects of this therapy have not been confirmed. The purpose of this study is to construct an intravascular injection embolism model and observe the effectiveness of warm and cold compress through a randomized, controlled trial. Thirty rabbit’s sixty ears were randomly divided into warm compress group, cold compress group, and control group. Polymethyl methacrylate (PMMA) was slowly injected into the central ear artery (CEA) to cause vascular embolism. Warm compress and cold compress treatment were performed respectively. The vascular recanalization and other related indexes were observed at 30 min, 1 day, and 7 days after injection, and the tissue necrosis was analyzed at 7 days. In the early stage of vascular embolization, warm compress can immediately promote vascular dilatation, blood circulation and partial blood flow recovery. One day after intravascular injection, warm compress can reduce intravascular embolization and reduce the incidence of tissue necrosis. At 7 days after intravascular injection, the vessels in the cold compress and control groups were still embolized while the percentage of recanalization in the warm compress group was 47.4% (P < 0.000). Early-stage warm compress after intravascular PMMA injection is conducive to recanalization of vascular embolization and reducing tissue necrosis.
TRPM8 thermosensation in poikilotherms mediates both skin colour and locomotor performance responses to cold temperature
Authors: Malik Hannan R. , Bertolesi Gabriel E. , McFarlane Sarah 
Published: January 2023

AbstractThermoregulation is a homeostatic process to maintain an organism’s internal temperature within a physiological range compatible with life. In poikilotherms, body temperature fluctuates with that of the environment, with both physiological and behavioral responses employed to modify body temperature. Changing skin colour/reflectance and locomotor activity are both well-recognized temperature regulatory mechanisms, but little is known of the participating thermosensor/s. We find that Xenopus laevis tadpoles put in the cold exhibit a temperature-dependent, systemic, and rapid melanosome aggregation in melanophores, which lightens the skin. Cooling also induces a reduction in the locomotor performance. To identify the cold-sensor, we focus on transient receptor potential (trp) channel genes from a Trpm family. mRNAs for several Trpms are present in Xenopus tails, and Trpm8 protein is present in skin melanophores. Temperature-induced melanosome aggregation is mimicked by the Trpm8 agonist menthol (WS12) and blocked by a Trpm8 antagonist. The degree of skin lightening induced by cooling is correlated with locomotor performance, and both responses are rapidly regulated in a dose-dependent and correlated manner by the WS12 Trpm8 agonist. We propose that TRPM8 serves as a cool thermosensor in poikilotherms that helps coordinate skin lightening and behavioural locomotor performance as adaptive thermoregulatory responses to cold.
A vein wall cell atlas of murine venous thrombosis determined by single-cell RNA sequencing
Authors: DeRoo Elise , Zhou Ting , Yang Huan , Stranz Amelia , Henke Peter , Liu Bo 
Published: January 2023

AbstractDeep vein thrombosis (DVT) is a common clinical problem, but its cellular and molecular mechanisms remain incompletely understood. In this study, we performed single-cell RNA sequencing on mouse inferior vena cava (IVC) 24 h after thrombus-inducing IVC ligation or sham operation. 9 cell types composed of multiple subpopulations were identified. Notable transcriptomic changes induced by DVT included a marked inflammatory response, elevated hypoxia, and globally reduced myogenesis. Analysis of individual cell populations revealed increased inflammation and reduced extracellular matrix production across smooth muscle cells and fibroblasts, juxtaposed against an early phenotypic shift in smooth muscle cell populations away from a contractile state. By characterizing the transcriptomic changes in the vein wall during acute venous thrombosis at the single-cell level, this work provides novel insights into early pathological events in the vein wall that may potentiate thrombus formation and result in long term adverse venous remodeling.
Cytotoxicity of Carvotacetones from Sphaeranthus africanus Against Cancer Cells and Their Potential to Induce Apoptosis
Authors: Tran Huyen Thi , Kretschmer Nadine , Huynh Loi , Bauer Rudolf 
Published: January 2023

AbstractThree carvotacetones (1 – 3) isolated from Sphaeranthus africanus were screened in 60 cancer cell lines at the National Cancer Institute (NCI) within the Developmental
Therapeutics Program (DTP). At the concentration of 10−5 M, compound 1 (3,5-diangeloyloxy-7-hydroxycarvotacetone) turned out to be the most active compound against ACHN and
UO-31 renal cancer cell lines with growth percent values of − 100% (all cells dead). Compound 2 (3-angeloyloxy-5-[2″,3″-epoxy-2″-methylbutanoyloxy]-7-hydroxycarvotacetone) showed
strong effects in SK-MEL-5 melanoma and ACHN renal cancer cells with inhibition values of 93% and 97%, respectively. Compound 3
(3-angeloyloxy-5-[3″-chloro-2″-hydroxy-2″-methylbutanoyloxy]-7-hydroxy-carvotacetone) exhibited a quite strong effect on renal cancer cells with a growth inhibitory effect of 96% against
ACHN and UO-31 cells. When treated with five different concentrations of 1 (1 × 10−8, 1 × 10−7, 1 × 10−6, 1 × 10−5, and
1 × 10−4 M), HOP-92 cells were found to be most sensitive with GI50, TGI, and LC50 values of 0.17, 0.40, and 0.96 µM, respectively. When using the ApoTox-Glo
triplex assay to evaluate the apoptosis inducing effects of seven carvotacetones isolated from S. africanus in CCRF-CEM cells, compounds 1 – 6 increased caspase-3/7
activity with 1, 2, and 4 (3-angeloyloxy-5,7-dihydroxycarvotacetone) exhibiting the highest activitiy, indicating induction of caspase-dependent apoptosis.
Magnetic skyrmions in FePt square-based nanoparticles around room-temperature
Authors: Tyrpenou Christos , Stavrou Vasileios D , Gergidis Leonidas N 
Published: January 2023

Abstract
Magnetic skyrmions formed at temperatures around room temperature in square-based parallelepiped magnetic FePt nanoparticles with perpendicular magnetocrystalline anisotropy (MCA) were studied during the magnetization reversal process using micromagnetic simulations. Finite differences method were used for the solution of the Landau–Lifshitz–Gilbert equation. Magnetic configurations exhibiting Néel skyrmionic formations were detected. The magnetic skyrmions can be created in different systems by the variation of external field, side length and width of the squared-based parallelepiped magnetic nanoparticles. Micromagnetic configurations revealed a variety of states which include skyrmionic textures with one distinct skyrmion formed and stabilized for a range of external fields around room-temperature. The size of the nucleated Néel skyrmion is calculated as a function of the external field, temperature, MCA and nanoparticle’s geometrical characteristic lengths which can be adjusted to produce skyrmions on demand having diameters down to 12 nm. The micromagnetic simulations revealed that stable skyrmions in the temperature range of 270–330 K can be created for FePt magnetic nanoparticle systems lacking of chiral interactions such as Dzyaloshinskii–Moriya.
Enhanced generalized nonlinear sparse spectrum based on dual-tree complex wavelet packet transform for bearing fault diagnosis
Authors: Yang Zujie , Zhang Zongzhen , Wang Jinrui , Han Baokun , Liu Zongling , Ma Hao , Xing Shuo 
Published: January 2023

Abstract
The generalized nonlinear sparse spectrum (GNSS), as an improved fast kurtogram (FK) method, effectively suppresses the interference of abnormal signals through nonlinear preprocessing and sparse enhancement. However, the GNSS method inherits the shortcoming of the traditional FK method, using finite impulse response filters to process nonstationary signals, which limits the accuracy of fault extraction. Therefore, more precise filters should be developed to further improve the performance of fault features. Inspired by this, this paper introduces the dual-tree complex wavelet packet transform (DTCWPT) into the sparse spectrum, and proposes an enhanced generalized nonlinear sparse spectrum (EGNSS) for bearing fault diagnosis. Firstly, nonlinear preprocessing is performed on the input signal to weaken the interference of abnormal impacts. Secondly, the generalized pq-mean value of each subband obtained by DTCWPT is calculated. Finally, the sparse spectrum is constructed and the signal reconstruction is performed on the frequency band where the maximum generalized pq-mean value is located for the envelope analysis. Simulation signals and experimental bearing fault signals have been applied to demonstrate the superiority of the proposed EGNSS in improving fault performance and accuracy.
Recent advances and perspectives in GNSS PPP-RTK
Authors: Hou Pengyu , Zha Jiuping , Liu Teng , Zhang Baocheng 
Published: January 2023

Abstract
Precise point positioning-real-time kinematic (PPP-RTK), otherwise known as integer ambiguity resolution-enabled precise pointing positioning, has attracted much attention in recent years and has become state-of-the-art in the global navigation satellite system (GNSS) high-precision positioning community. This work reviews several PPP-RTK methods, outlines a set of PPP-RTK applications, and presents possible future developments. According to the parameterization considered, we clarify the PPP-RTK models into a distinct-clock category and two common-clock categories (common-clock-1 and common-clock-2), in which several ionosphere-free PPP-RTK models can be cast. Compared with the ionosphere-free PPP-RTK model, we emphasize the advantages of the undifferenced and uncombined (UDUC) formulation and recommend the common-clock-1 UDUC PPP-RTK model since it is optimal, flexible, and widely applicable. Based on what kinds of parameters can be estimated by PPP-RTK models, we outline the PPP-RTK applications in several aspects, including position-based applications, time transfer, atmospheric retrieval, and GNSS bias estimation. Despite the huge advances in GNSS PPP-RTK, future research should improve PPP-RTK performances in harsh environments and apply PPP-RTK to mass markets.
Low-interference real-time at-line spectroscopic composition analysis for chemical plants
Authors: Bogatykh Innokentij , Illner Markus , Nagler Franz-Josef , Stein Hendrik , Osterland Thomas , Repke Jens-Uwe 
Published: January 2023

Abstract
A novel system for composition analysis in chemical plants at high temperatures and pressures has been developed. The system uses heated capillaries to extract and transport liquid and gaseous samples to a Fourier-transform-infrared-spectrometer (FTIR) for analysis. The samples are extracted from pressure vessels at temperatures ranging from 20 °C to 190 °C and pressures from 5 to 22 bar and analyzed via FTIR with a dead time of 5–10 s. The system was successfully used to monitor the dehydration reaction of methanol to dimethyl ether in a reactive distillation column in a 170 h long-term experiment. The system has a measurement range of 1 × 10−4 mol mol−1 to 1 mol mol−1 and is accurate and fast enough for real-time product quality assessment and control in high purity chemical processes where inline measurements are challenging due to harsh environments.