bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growing the Forests on Agricultural Land in Russia: Legislative Novelties and Implementation Thereof
Authors: Rodina M. E. , Zakalyuzhnaya N. V. 
Published: July 2023

Introduction. For a long time the application of the extensive land and forest management at the abandoned agricultural land had no respective legislative framework, that would regulate forests growing. The proprietors, who were in despair due to the excessive fines imposed on them for not using the agricultural land, had been burning up the forests on their lands causing considerable damage to themselves, society, the state and nature. In Russia, the area of the abandoned agricultural land suitable for forestry is about 76 million hectares. In 2020 two extremely important regulatory legal documents concerning the forests located on the agricultural land not used in compliance with its intended purpose were adopted – the Russian Federation Government Decree No 1509 of September 21, 2020 (hereinafter – Decree No 1509) and the Russian Federation Government Decree No 1482. The business entities (including the proprietors and forest managers) interested in development of this sector have noted the positive dynamics in the legislation development because of the profound opportunities opened for forests multiplication –– there appeared the opportunities for forest farming and growing the forests on the abandoned agricultural land, setting-up the nursery forests, developing the rural territories, particularly in the Non-Black-Soil zone, all of these can benefit the Russian forests stock, preserve biodiversity and, not the least, improve the overall ecological and climate situation in the country and in the world. By the beginning of 2023, this sector of legal relationships has been significantly amended by the legislators, however it should be noted, that the legal regulation and settlement of many issues in this sector still remain difficult. The aim of the present research is to distinguish the problematic issues in development of the Russian Federation agroforestry legislation and implementation of the Russian Federation Government Decree No 1509 of September 21, 2020.Materials and Methods. In the article, the issue of growing the forests on agricultural land was analysed. The general scientific and specific scientific methods were used in the research. The methodology of the study was based on the dialectical method, as well as on the legalistic, comparative-legal, system-structural kinds of analysis.Results. It was revealed, that the formidable administrative and regulatory barriers have been set forth the agroforestry evolvement and this sector of the legislation development needs serious reassessment. Urgent steps must be taken to identify all the gaps and shortcomings and to rectify the situation.Discussion and Conclusions. The problems caused by adding the numerous amendments to the Decree № 1509, complicating the forests growing on agricultural land, have been revealed. The transit to the intensive management of forests and removal of bureaucratic barriers in development of the agroforestry are deemed necessary.
Neurological manifestations of Degos disease
Authors: Abzalova D. I. , Sinkin M. V. , Kisyel O. V. , Grin A. A. 
Published: July 2023

Degos disease is a rare disease that manifests itself as multifocal vasculopathy, the consequence of which is the defeat of many systems, including the nervous system. This disease is difficult to diagnose, today it does not have a standardized approach to treatment, and it is deadly.In the presented clinical case, the course of BD is described in a 66-year-old patient, whose debut of the disease was a lesion of the skin. The cause of hospitalization of the patient was the defeat of the central nervous system. During the additional examination, the patient was diagnosed with ischemic stroke in the basin of the left middle cerebral artery, posterior cerebral artery, right middle cerebral artery of another established etiology according to TOAST, aseptic leptomeningitis, pachymeningitis. The course of the disease was complicated by damage to the gastrointestinal tract, the cardiovascular system, as well as the addition of a coronavirus infection, which led to death.
Design and Development of Different Applications of PATB (Porous Aerostatic Thrust Bearing): A Review
Authors: CHAKRABORTY MR. BIVASH , CHAKRABORTI DR. PRASUN 
Published: July 2023

In several applications demanding precise and ultra-precision movements, porous aerostatic thrust bearings had been employed as a crucial precision engineering component and enabling technology. By acting as a lubricant between the moving part and the stationary part in aerostatic bearings, pressurized air almost completely eliminates friction. Since air acts as the lubricant, oil-based lubricants leave no debris behind. The air prolongs the life of the substances by preventing them from slipping and wearing. The aerostatic type uses graphite as a porous film to disrupt the air uniformly over the surface, or a tiny hole is drilled through the centre of the bearing to let the air circulate and produce a thin layer between the components. With an increased reliance on computational and mathematical methodologies for design and bearing performance optimization, this review paper aims to present the state-of-the-art in aerostatic bearings advancement and research. It also conducts a critical analysis of their future research directions and development trends in the next ten years and beyond. Air bearings are utilized in the production of tools like lathes, CMM, and grinders because they are highly precise in their operation and decrease mistakes and production time. Air bearings are available in a variety of forms and sizes. The assessment of future trends and obstacles in aerostatic bearings investigation, as well as their prospective applications in the precision engineering sectors, concludes the study.
Effect of Long Extended Working Hours on the Occupational Health and Safety of Oil and Gas Workers in the Sultanate of Oman
Authors: Palathoti Suvarnaraju , Al Aghbari Abdullah Hamed Muhanna , Otitolaiye Victor O. 
Published: July 2023

Introduction: Oil and Gas workers are exposed to numerous hazards which impede their productivity; one such hazard these workers are exposed to is long or extended working hours. Hence, this paper examined the impacts of extended working hours on workers' occupational health and safety at a selected oil and gas company in Oman. Consequently, the workers’ opinions on the impacts of extended working hours at the company were critically analyzed to draw potential inferences and proffer solutions to the problem in Oman. The study aimed to critically identify, assess, and highlight the occupational safety problems associated with extended working hours among workers at a selected oil and gas company in Oman.
Methods: A total of 128 respondents were randomly selected from the 140 employees and company managers through administered questionnaires. Data collection was done between January 25 and February 30, 2022. The questionnaire consisted of five items statements based on the four-agreement or Likert scale of measurement.
Results: A response rate of 91% was derived from the questionnaire administered for the study. Results from data analysis indicated that 73% of the respondents were male while 27% were female. Furthermore, the results indicated that extended working hours have substantial impacts on family life (s=54%), performance (s=68%), productivity, and health of the workers. Extended working hours potentially expose workers to various dangers which bring about numerous adverse effects (stress, fatigue, depression, and loss of concentration) on their occupational health and safety.
Conclusion: It is recommended that oil and gas companies establish occupational health and safety guidelines to limit the work times and duration (i.e., time spent at work) through shorter shifts, longer breaks, or extended leaves. Long working hours should be prohibited except on special occasions or unavoidable circumstances to safeguard the health and well-being of staff, which could ultimately enhance the productivity and output of the company.
ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression
Authors: Lavy Margot , Gauttier Vanessa , Dumont Alison , Chocteau Florian , Deshayes Sophie , Fresquet Judith , Dehame Virginie , Girault Isabelle , Trilleaud Charlène , Neyton Stéphanie , Mary Caroline , Juin Philippe , Poirier Nicolas , Barillé-Nion Sophie , Blanquart Christophe 
Published: July 2023

IntroductionTumor Associated Macrophages (TAM) are a major component of the tumor environment and their accumulation often correlates with poor prognosis by contributing to local inflammation, inhibition of anti-tumor immune response and resistance to anticancer treatments. In this study, we thus investigated the anti-cancer therapeutic interest to target ChemR23, a receptor of the resolution of inflammation expressed by macrophages, using an agonist monoclonal antibody, αChemR23.MethodsHuman GM-CSF, M-CSF and Tumor Associated Macrophage (TAM)-like macrophages were obtained by incubation of monocytes from healthy donors with GM-CSF, M-CSF or tumor cell supernatants (Breast cancer (BC) or malignant pleural mesothelioma (MPM) cells). The effects of αChemR23 on macrophages were studied at the transcriptomic, protein and functional level. Datasets from The Cancer Genome Atlas (TCGA) were used to study CMKLR1 expression, coding for ChemR23, in BC and MPM tumors. In vivo, αChemR23 was evaluated on overall survival, metastasis development and transcriptomic modification of the metastatic niche using a model of resected triple negative breast cancer.ResultsWe show that ChemR23 is expressed at higher levels in M-CSF and tumor cell supernatant differentiated macrophages (TAM-like) than in GM-CSF-differentiated macrophages. ChemR23 activation triggered by αChemR23 deeply modulates M-CSF and TAM-like macrophages including profile of cell surface markers, cytokine secretion, gene mRNA expression and immune functions. The expression of ChemR23 coding gene (CMKLR1) strongly correlates to TAM markers in human BC tumors and MPM and its histological detection in these tumors mainly corresponds to TAM expression. In vivo, treatment with αChemR23 agonist increased mouse survival and decreased metastasis occurrence in a model of triple-negative BC in correlation with modulation of TAM phenotype in the metastatic niche.ConclusionThese results open an attractive opportunity to target TAM and the resolution of inflammation pathways through ChemR23 to circumvent TAM pro-tumoral effects.
A root-knot nematode effector manipulates the rhizosphere microbiome for establishing parasitism relationship with hosts
Authors: Liu Rui , Chen Mengfei , Liu Boliang , Huang Kaiwei , Mao Zhenchuan , Li Huixia , Zhao Jianlong 
Published: July 2023

IntroductionRoot-knot nematode (RKN; Meloidogyne spp.) is one of the most infamous soilborne plant diseases, causing severe crop losses every year. Effector proteins secreted by RKNs play crucial roles during plant-nematode interaction. However, less is known about whether RKN effector proteins can impact the rhizosphere microbial environment.MethodsIn this study, we investigated the rhizosphere microbiome community of MiMIF-2 (a plant immunity-modulating effector) transgenic Arabidopsis thaliana with or without nematode infection using the Illumina high-throughput sequencing analysis.Results and discussionThe results showed that the bacterial species richness index increased, while the fungi species richness index decreased in M. incognita-infected MiMIF-2 transgenic A. thaliana plants. The relative abundance of genera such as Clitopilus, Komagataeibacter, Lactobacillus, Prevotella, Moritella, Vibrio, Escherichia-Shigella, and Pseudomonas was reduced in MiMIF-2 transgenic A. thaliana plants compared to wild type, but was significantly increased after inoculation with M. incognita. The Cluster of Orthologous Genes (COG) function classification analysis revealed a decrease in the relative abundance of defense mechanisms, secondary metabolite biosynthesis, transport, and nematode infection catabolism-related functions in MiMIF-2 lines compared to the wild type. These differences may be the reason for the increased susceptibility of MiMIF-2 transgenic A. thaliana to nematode infection. Our results provide a new insight into RKN effector proteins and their association with the microbial community, host, and plant pathogens, which will lead to the exploration of new innovative ideas for future biological control of RKNs.
Dynamics of PO2 and VO2 in resting and contracting rat spinotrapezius muscle
Authors: Golub Aleksander S. , Song Bjorn K. , Nugent William H. , Pittman Roland N. 
Published: July 2023

This study examined changes in interstitial PO2, which allowed calculation of VO2 during periods of rest, muscle contraction and recovery using an in situ rat spinotrapezius muscle preparation. The PO2 was measured using phosphorescence quenching microscopy and the muscle VO2 was calculated as the rate of O2 disappearance during brief periods of muscle compression to stop blood flow with a supra-systolic pressure. The PO2 and VO2 measurements were made during “5 s compression and 15 s recovery” (CR) cycles. With all three stimulation frequencies, 1, 2 and 4 Hz, the fall in interstitial PO2 and rise in VO2 from resting values occurred within the first 20 s of contraction. The PO2 during contraction became lower as stimulation frequency increased from 1 to 4 Hz. VO2 was higher at 2 Hz than at 1 Hz contraction. With cessation of stimulation, PO2 began increasing exponentially towards baseline values. After 1 and 2 Hz contraction, the fall in muscle VO2 was delayed by one CR cycle and then exponentially decreased towards resting values. After 4 Hz stimulation, VO2 increased for 2 cycles and then decreased. The post-contraction transients of PO2 and VO2 were not synchronous and had different time constants. With further analysis two distinct functional responses were identified across all stimulation frequencies having PO2 during contraction above or below 30 mmHg. The corresponding VO2 responses were different - for “high” PO2, muscle VO2 reached high levels, while for the “low” PO2 data set muscle VO2 remained low. Recovery patterns were similar to those described above. In summary, local microscopic PO2 and VO2 were measured in resting and contracting muscle in situ and the post-contraction transients of PO2 and VO2 were all much slower than the onset transients.
Using the photoplethysmography method to monitor age-related changes in the cardiovascular system
Authors: Djurić Biljana , Žikić Katarina , Nestorović Zorica , Lepojević-Stefanović Danijela , Milošević Nebojša , Žikić Dejan 
Published: July 2023

Introduction: Aging is a physiological process characterized by progressive changes in all organ systems. In the last few decades, the elderly population has been growing, so the scientific community is focusing on the investigation of the aging process, all in order to improve the quality of life in elderly. One of the biggest challenges in studying the impact of the aging on the human body represents the monitoring of the changes that inevitably occur in arterial blood vessels. Therefore, the medical community has invested a great deal of effort in studying and discovering new methods and tools that could be used to monitor the changes in arterial blood vessels caused by the aging process. The goal of our research was to develop a new diagnostic method using a photoplethysmographic sensor and to examine the impact of the aging process on the cardiovascular system in adults. Long-term recorded arterial blood flow waveforms were analyzed using detrended fluctuation analysis.Materials and Methods: The study included 117 respondents, aged 20–70 years. The waveform of the arterial blood flow was recorded for 5 min, with an optical sensor placed above the left common carotid artery, simultaneously with a single-channel ECG. For each cardiac cycle, the blood flow amplitude was determined, and a new time series was formed, which was analyzed non-linearly (DFA method). The values of the scalar coefficients α1 and α2, particularly their ratio (α1/α2) were obtained, which were then monitored in relation to the age of the subjects.Result: The values of the scalar ratio (α1/α2) were significantly different between the subjects older and younger than 50 years. The value of the α1/α2 decreased exponentially with the aging. In the population of middle-aged adults, this ratio had a value around 1, in young adults the value was exclusively higher than 1 and in older adults the value was exclusively lower than 1.Conclusion: The results of this study indicated that the aging led to a decrease in the α1/α2 in the population of healthy subjects. With this non-invasive method, changes in the cardiovascular system due to aging can be detected and monitored.
Adolescent mentalizing and childhood emotional abuse: implications for depression, anxiety, and borderline personality disorder features
Authors: Martin-Gagnon Gabriel , Normandin Lina , Fonagy Peter , Ensink Karin 
Published: July 2023

BackgroundThere is preliminary evidence that childhood emotional abuse (CEA) is a risk factor for adolescent mentalizing difficulties (Uncertainty/Confusion about mental states) and borderline personality features and that Uncertainty/Confusion about mental states mediate the relationship between CEA and adolescent borderline personality features, but these findings need replication. Furthermore, no previous studies have examined the relationship between adolescent mentalizing deficits, anxiety, and depression in the context of CEA.ObjectivesThis study examined the associations between CEA, adolescent borderline personality features, depression and anxiety symptoms and tested a pathway model where Uncertainty/Confusion about mental states mediates the relationships between CEA and adolescent borderline personality features, depression and anxiety symptoms.MethodA clinical sample of 94 adolescents completed the Reflective Function Questionnaire for Youth (RFQY) to assess mentalizing, the Childhood Experiences of Care and Abuse Questionnaire (CECA-Q), the Borderline Personality Disorders Features Scale (BPFS-C), and the Beck Youth Inventories for Depression (BDI-Y) and Anxiety (BAI-Y).ResultsUncertainty/Confusion about mental states partially mediated the relationship between CEA and borderline traits as well as anxiety. In addition, there was an indirect effect where CEA predicted Uncertainty/Confusion about mental states, which then predicted depression.DiscussionThe findings are consistent with the mentalizing model of psychopathology and provide new evidence that Uncertainty/Confusion about mental states might be a critical mentalizing deficit that characterizes the associations between CEA and adolescent BPD features and depression and anxiety symptoms. Uncertainty/Confusion may be a transdiagnostic risk factor for adolescent psychological distress and dysfunction. We discuss the clinical implications.
Physical and mental health conditions account for variability in awareness of age-related changes
Authors: Sabatini Serena , Turner Shelbie , Brooker Helen , Ballard Clive , Corbett Anne , Hampshire Adam 
Published: July 2023

BackgroundThe concept of Awareness of Age-Related Changes captures people’s perceptions of the positive (AARC-gains) and negative (AARC-losses) age-related changes they experience in several life domains, including their health. We investigated the cross-sectional associations of number and type of physical and mental health conditions with AARC-gains and AARC-losses.MethodsThe sample comprised 3,786 middle-aged and older adults (mean age = 67.04 years; SD = 6.88) participating to the UK PROTECT study. We used hierarchical regression models to analyze whether after having included sociodemographic variables (model 1), number of physical (model 2) and of mental (model 3) health conditions explained a significant additional amount of variance in AARC-gains and AARC-losses, and whether the association between number of conditions and AARC depended on participants’ age. We used multiple regression models to analyze the associations of types of physical and mental health conditions with AARC-gains and AARC-losses.ResultsA higher number of physical health conditions was associated with higher AARC-gains and higher AARC-losses, but the association did not depend on participant age. After controlling for the number of physical health conditions, a higher number of mental health conditions was associated with higher AARC-losses but not with AARC-gains, and the association was stronger among older participants. Small effects were found between greater AARC-gains and current cancer and between greater AARC-losses and diagnoses of mild cognitive impairment, Parkinson’s disease, arthritic condition, cancer in full remission, osteoporosis, depression, anxiety disorders, and personality disorder. The remaining health conditions were either negligibly or non-statistically related to AARC-losses.ConclusionMiddle-aged and older adults having more physical health conditions and more mental health conditions may be at higher risk of negative views on their own aging. However, specific physical health conditions, such as arthritis, and certain mental health conditions, such as depression, may make adults particularly vulnerable to negative age-related perceptions.
Factors affecting decreased physical activity during the COVID-19 pandemic: an age-, gender-, and body mass index-matched study
Authors: Shin Jhin-Yi , Lee Jaemoo , Lee Jung-Min , Ho Nam Yoon 
Published: July 2023

PurposeThis study aims to investigate the association between factors affecting decreased physical activity (PA) during the COVID-19 pandemic by matching groups based on age, gender, and BMI variables using public Community Health Survey (CHS) data.MethodsData from the CHS was selected and used to investigate health-related factors related to PA, including demographic, psychological, behavioral characteristics, sociocultural, and chronic disease. Exact group matching was conducted based on age, gender, and BMI variables. Frequency analysis, Chi-square test (χ2 test), and multinominal logistic regression analysis were performed to analyze the data, and odds ratio (OR) and 95% confidence interval (95% CI) were presented. The study also examined the impact of COVID-19 on PA, the fear of PA infection.ResultsThe logistic regression analysis by gender showed that PA decreased in all age groups, males, and females during the COVID-19 pandemic. The decrease in PA was lower in age groups other than those aged 60 or older. Stress experience, residence area, housing type, drinking, smoking, education level, and fear of infection were found to affect decreased PA due to COVID-19. Specifically, experiencing stress (Odds Ratio [OR] = 1.178; 95% Confidence Interval [CI] = 1.054 ~ 1.317) and increased smoking (OR = 1.332; 95% CI = 1.073 ~ 1.653) had a slightly higher impact on decreased PA. Conversely, living in a suburban area (OR = 0.653; CI = 0.585 ~ 0.728), having public housing (OR = 0.836; CI = 0.754 ~ 0.928), having less than a high school education (OR = 0.813; CI = 0.729 ~ 0.907), staying the same with alcohol (OR = 0.567; CI = 0.507 ~ 0.633) and smoking (OR = 0.836; CI = 0.728 ~ 0.959), and having low fear of infection (OR = 0.817; CI = 0.737 ~ 0.905) had a slightly lower impact on decreased PA.ConclusionPA should be maintained or increased, particularly in the context of social distancing measures during the pandemic. To ensure that PA can be sustained, a program should be developed that considers the individual’s geographical location, economic status, lifestyle, and environment.