bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis, Antimicrobial and Antioxidant Activity of Some New
Pyrazolines Containing Azo Linkages
Authors: Hussein Awaz Jamil 
Published: August 2023

Background:
Pyrazolines and azo-pyrazolines are influential groups of heterocyclic compounds with two nitrogen atoms inside the five-membered ring. They play an important role in a wide range of biological processes, such as antifungal, antioxidant, antimalarial and other antimi-crobial activities.

Objective:
The main objective of this study is to synthesize some new heterocyclic compounds with antioxidant and antimicrobial activity.

Methods:
One-pot three components and traditional synthesis of new azo-pyrazoline compounds were achieved in this work. The preparation process has been started by diazotizing 4-(6-methylbenzothiazol-2-yl) benzamine and its coupling reaction with 4-hydroxy acetophenone pro-ducing azo-acetophenone, followed by benzylation with benzyl chloride to form the starting materi-al, azo-benzyloxy acetophenone. A series of substituted benzaldehydes were reacted with the latter compound via one pot and classical methods, forming new chalcones containing azo linkages and benzyloxy moieties, which were then converted into new target azo-pyrazoline derivatives.

Results:
The structures of the synthesized compounds were confirmed by spectroscopic techniques using FT-IR, 1H-NMR, 13C-NMR, and 13C- DEPT- 135 spectra. Finally, the synthesized compounds were screened for their antioxidant and antimicrobial activities against Staphylococcus aureus and Escherichia coli.

Conclusion:
Overall, the one-pot three-component synthesis of pyrazoline compounds generally provides advantages in terms of efficiency, simplicity, and time-consumption compared to classical synthesis methods. Hence, the study advocates the one-pot method because it eliminates the tedious process of making chalcones, which takes time, materials, and unnecessary effort. Therefore, this is the most convenient and effective approach to green chemistry.
A Tunable Plasmonic Perfect Absorber based on Graphene and Two
Metal-insulator Substructures
Authors: Madadi Zahra , Lafmejani Samaneh Rasoolian 
Published: August 2023

Background:
In recent decades, numerous researchers have been keenly interested in
plasmonic absorbers due to their efficiency in a variety of applications such as solar cells. This is
because the surface plasmons formed at the interface between metal and insulators interact strongly
with light, thereby augmenting electromagnetic (EM) waves. In most cases, plasmonic absorbers
featuring metal-insulated-metal structure (MIM) are favored for their robust absorption rates,
straightforward fabrication process, minuscule size, and portability.

Methods:
This paper proposes a tunable plasmonic perfect absorber (PPA) based on graphene and
two metal-insulator substructure within the 28-60 μm wavelength range. This device is simulated
by 3D finite element analysis using CST software. Also, in our proposed structure, instead of using
a single micro-blade, two micro-blades are arranged opposite of each other in the absorber
structure through which the electric field is locally strengthened and a sharper resonance peak
with greater amplitude is obtained.

Results:
Simulation results demonstrate that a resonance peak is observable in the absorption
spectrum of the structure and that this peak can be shifted between 30μm and 40μm by applying a
gate bias voltage to the graphene nanolayer without modification of the structure's dimensions.

Conclusion:
The features of this absorber make it suitable for sensor applications, which will be
further explored in future research. We also investigated the influence of dimensions on absorption
to take into account the allowable tolerances and sensitivities associated with its fabrication.
Furthermore, we proposed a structure that can enhance absorber performance in the future.
Delphi Survey of Items for the Test of Stuttering Screening in Children (TSSC)
Authors: Varghese Aiswarya Liz , Balasubramanium Radish Kumar , Bajaj Gagan , Karuppali Sudhin , Bhaskaran Unnikrishnan 
Published: August 2023

Purpose:
Stuttering is a fluency disorder that mostly begins in childhood and affects many people in our societies. No standardized screening tools are available to check for stuttering in the Indian school-going population. Thus, the study aimed at developing a screening tool to identify children who stutter among the school-going population using a Delphi-based approach.

Methods:
This study was carried out in four phases. During the first phase, five Speech Language Pathologists (SLPs) were asked about the need for screening and the nature & attributes of a stuttering screening test for school-going children. The second phase involved constructing appropriate stimuli for the screening tool based on expert opinion, relevant literature and students’ academic textbooks. The third phase involved content validation of the speech elicitation stimuli by four teachers, five SLPs and an English Lecturer teaching in a university. The fourth phase encompassed the development of differential diagnosis criteria for stuttering identification in children using a rank analysis of the expert opinions.

Results:
A stuttering screening stimuli comprising age, language and culture-specific reading, picture description and narration tasks for 1st to 10th-standard students was developed. The contents of the tool obtained satisfactory consensus of agreement among the panel of experts. Further, the tool outlined five critical diagnostic criteria which could differentially diagnose school-going children with stuttering from typically speaking counterparts using the developed material.

Conclusion:
The developed screening tool could help practicing clinicians quickly identify stuttering in school-going populations. This would enable early identification and build up the statistical data to estimate the prevalence of stuttering among the school-going population. Further studies examining the psychometric properties of the developed test are in progress.
A Beta-Prototype Chatbot for Increasing Health Literacy of Patients With Decompensated Cirrhosis: Usability Study
Authors: Au Jessica , Falloon Caitlin , Ravi Ayngaran , Ha Phil , Le Suong 
Published: August 2023

Background
Health literacy is low among patients with chronic liver disease (CLD) and associated with poor health outcomes and increased health care use. Lucy LiverBot, an artificial intelligence chatbot was created by a multidisciplinary team at Monash Health, Australia, to improve health literacy and self-efficacy in patients with decompensated CLD.

Objective
The aim of this study was to explore users’ experience with Lucy LiverBot using an unmoderated, in-person, qualitative test.

Methods
Lucy LiverBot is a simple, low cost, and scalable digital intervention, which was at the beta prototype development phase at the time of usability testing. The concept and prototype development was realized in 2 phases: concept development and usability testing. We conducted a mixed methods study to assess usability of Lucy LiverBot as a tool for health literacy education among ambulatory and hospitalized patients with decompensated CLD at Monash Health. Patients were provided with free reign to interact with Lucy LiverBot on an iPad device under moderator observation. A 3-part survey (preuser, user, and postuser) was developed using the Unified Acceptance Theory Framework to capture the user experience.

Results
There were 20 participants with a median age of 55.5 (IQR 46.0-60.5) years, 55% (n=11) of them were female, and 85% (n=17) of them were White. In total, 35% (n=7) of them reported having difficulty reading and understanding written medical information. Alcohol was the predominant etiology in 70% (n=14) of users. Participants actively engaged with Lucy LiverBot and identified it as a potential educational tool and device that could act as a social companion to improve well-being. In total, 25% (n=5) of them reported finding it difficult to learn about their health problems and 20% (n=4) of them found it difficult to find medical information they could trust. Qualitative interviews revealed the conversational nature of Lucy LiverBot was considered highly appealing with improvement in mental health and well-being reported as an unintended benefit of Lucy LiverBot. Patients who had been managing their liver cirrhosis for several years identified that they would be less likely to use Lucy LiverBot, but that it would have been more useful at the time of their diagnosis. Overall, Lucy LiverBot was perceived as a reliable and trustworthy source of information.

Conclusions
Lucy LiverBot was well received and may be used to improve health literacy and address barriers to health care provision in patients with decompensated CLD. The study revealed important feedback that has been used to further optimize Lucy LiverBot. Further acceptability and validation studies are being undertaken to investigate whether Lucy LiverBot can improve clinical outcomes and health related quality of life in patients with decompensated CLD.
Exploring the Benefits for First-Year University Students Joining Peer Groups: A case study of a South African University
Authors: Mntuyedwa Vuyokazi 
Published: August 2023

Abstract
This study focused on the benefits for first-year university students who lived in the university residences at a South African University joining peer groups. A qualitative approach was adopted through a case study research design. Qualitative data were collected from first-year students in 2017 through three focus group interviews with females only, males only and mixed gender in two first-year residences at a selected South African university. The qualitative data were analysed using thematic analysis. The findings reveal the benefits for first-year students joining peer groups in the residences at the South African university, which include gaining a sense of belonging, receiving academic support, developing student leadership roles, and involving co-curricular activities. The study supports the need for implementing enchanted first-year student programs to assist first-year students in transitioning to higher education and decrease dropout rates.
Challenges confronting students during COVID 19: insights from social workers at a University of Technology
Authors: Bhagwan Raisuyah 
Published: August 2023

Abstract

University students were regarded as a vulnerable population, who endured greater levels of mental health problems and financial distress in addition to the academic challenges of transitioning to online learning methodologies during the COVID-19 pandemic. Hence, the tumultuous nature of the pandemic and consequent sheltering in place and other disruptions placed a huger burden on this vulnerable population. Using qualitative research methodologies, this study sought to explore the challenges faced by students, through the lens of social workers who were placed at a University of Technology during the pandemic. Using purposive sampling techniques to recruit these practitioners the study further sought to enquire about what support measures were required to be in place, to enhance the well-being of students during the pandemic. Data was collected using semi-structured interviews and the analysis was guided by thematic analysis. The study found that students encountered an array of psychological problems, together with experiences of stigma, isolation whilst in quarantine which led the sample to call for the reconstruction of the university space into a more supportive one.
Acute kidney injury is common in dogs with septic peritonitis and is associated with increased mortality
Authors: Snipes Mary M. , Schmiedt Chad W. , Lourenço Bianca N. , Grimes Janet A. , Wallace Mandy L. , Sutherland Brian J. , Brainard Benjamin M. 
Published: August 2023

Abstract

OBJECTIVE
To identify the frequency of and risk factors for acute kidney injury (AKI) in dogs undergoing abdominal surgery for septic peritonitis, and to evaluate outcome and kidney-related risk factors for survival to discharge in those dogs.

ANIMALS
77 dogs that underwent abdominal surgery for septic peritonitis.

METHODS
Medical records of dogs that underwent surgery for septic peritonitis from 2012 through 2022 were reviewed. Data regarding signalment, clinical and biochemical findings at presentation, blood creatinine concentration throughout hospitalization, surgery characteristics, postoperative monitoring, and outcome were collected. Dogs were classified based on occurrence of AKI and whether they presented with or developed AKI in-hospital. Perioperative risk factors were evaluated, and outcomes were compared with univariable logistic regression.

RESULTS
31 dogs (40.3%) had AKI diagnosed; 18/77 (23.4%) dogs presented with AKI, 11 (61.1%) of which had it postoperatively, and 13/77 (16.9%) dogs developed AKI postoperatively. Significant factors for presenting with AKI included increasing baseline respiratory rate (OR 2.5 for every 10 beats per minute higher), decreasing systolic blood pressure (OR 0.8 for every 10 mm Hg higher), and increasing body condition score (OR 2.2 for every score greater). No significant factors for developing AKI postoperatively were identified after multiple comparisons adjustment. Sixteen dogs (20.8%) did not survive to discharge; 12 (75.0%) had AKI and 4 (25.0%) did not. Dogs with AKI had decreased odds of survival to discharge (OR 0.2).

CLINICAL RELEVANCE
AKI was common in dogs with septic peritonitis and was a significant risk factor for survival to discharge. Clinical surveillance of AKI is critical in this population.
FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN KEBERHASILAN PEMBERIAN ASI EKSKLUSIF OLEH IBU BEKERJA DI KOTA DENPASAR
Authors: Dewi Made Ayu Puspa , Puspita Luh Mira , Eva Yanti Ni Luh Putu 
Published: August 2023

A working mother is frequently facing barriers in breastfeeding their babies. Several barriers in breastfeeding faced by the working mothers are the long duration of work, the lack of opportunities and support provided by the workplace for mothers to do the breast milk due to the unavailability of breastfeeding facilities such as lactation rooms, and the lack of knowledge of working mothers regarding lactation management. This study aims to determine the factors associated with the success of exclusive breastfeeding by working mothers in Denpasar City. This study was quantitative correlative research by using a cross-sectional design and purposive sampling technique. Data collection was carried out on 97 respondents who visited Puskesmas 1 Denpasar Utara, Puskesmas 1 Denpasar Timur, Puskesmas 2 Denpasar Barat, and Puskesmas 2 Denpasar Selatan. Data collection used knowledge, availability of lactation facilities at work, and husband's support questionnaires. The eta test and contingency coefficient were used for the data analysis. The results showed that there was no correlation between age (p=0,08), parity (p=0,132), baby's gender (p=0,501), socioeconomic status (p=0,111), type of mother's occupation (p=0,70), knowledge (p=0,338), availability of lactation facilities (p=0,3), and husband's support (p=0,180) with exclusive breastfeeding. However, distance (0,019) and duration of work (p=0,044) were associated with exclusive breastfeeding (p<0,05). In conclusion, there is a relationship between distance and duration of work seem as predictors of exclusive breastfeeding by working mothers in Denpasar City. It is expected to increase knowledge of working mothers about the management of expressed breast milk, thus the exclusive breastfeeding can be achieved.
ESTIMASI MEJA DAPUR BETON
Authors: Rintawati Dewi , Hermawan Fahmi , Winoto Susianti , Prasetyo Ryan Faza , Safitri Ristya A. , Bernika Jovani 
Published: August 2023

Kelurahan Bendung Kecamatan Kasemen Kota Serang yang terdiri dari 4 kampung yaitu kampung Ciwedus, kampung lamaran, kampung Cibobomo dan kampung Sungak memiliki jumlah penduduk lebih dari delapan ribu orang. Sebagian besar penduduk wanita berprofesi sebagai ibu rumah tangga dan merangkap pedagang makanan dirumah maupun di pasar yang menghabiskan sebagian dari waktunya berada di dapur. Dapur sebagai bagian dari ruangan di perumahan memiliki peran besar dalam memenuhi kesehatan keluarga dengan menyajikan makanan yang sehat dan bersih. Kebutuhan akan makanan yang sehat dan bersih dihasilkan dari dapur yang memenuhi syarat kesehatan dan kebersihan. Salah satu alternatif yang ditawarkan adalah ruang dapur yang memiliki meja dapur yang terbuat dari material beton. Material beton selain kuat dan tahan lama juga tahan terhadap panas dan kedap air serta mudah pemeliharaannya.Tujuan pengabdian kepada masyarakat ini adalah untuk menambah pengetahuan masyarakat dan memberikan pemahaman tentang pembuatan meja dapur yang sehat, kuat dan tahan lama bagi masyarakat, mengestimasi biaya pembuatan dengan disain sederhana dan mudah dikerjakan serta memenuhi standar perhitungan yang berlaku. Material yang dipakai menggunakan beton sehingga mudah pemeliharaannya dan aman terhadap potensi jika terjadi kebakaran saat memasak. Terkait dengan Mitra maka diharapkan dengan pengetahuan mambangun dan mengestimasi meja dapur dari beton tersebut, masyarakat di Kelurahan Bendung akan mengimplementasikan pengetahuan tersebut dan terus ditularkan kepada masyarakat lain yang membutuhkan untuk menjamin bahwa ruang dapur dalam kondisi bersih, sehat, kuat dan tahan lama.
Access to justice regarding plans and programmes related to the environment – Polish law in the light of Article 9.3 of the Aarhus Convention
Authors: Bar Magdalena 
Published: August 2023

Article 9.3 of the Aarhus Convention grants members of the public (meeting certain requirements, if a Party to the Convention so specifies) access to a review procedure (access to justice) to challenge acts or omissions by private persons or public authorities that contravene provisions of its national law relating to the environment. According to Article 2.4 of the Convention, non-governmental organisations should also be considered as "members of the public".
According to the jurisprudence of the Aarhus Convention Compliance Committee, the activities of public authorities covered by the requirements of Article 9.3 of the Convention include adoption of plans and programmes which may have an impact on the environment.
In accordance with the Polish law (often following the requirements of EU law), administrative authorities adopt a whole range of plans and programmes relating to the environment or having an impact on the environment. These documents are developed either by regional or local authorities (self-governmental authorities or regional government administration) or at the central level.
Polish law provides very limited opportunities to challenge plans or programmes. With respect to documents created at the central level, there are no such possibilities at all, and with respect to documents created at lower levels, certain, limited, rights in this respect are granted only to private entities whose legal interest has been violated. The possibility for NGOs to challenge plans or programmes is completely excluded.
Such a situation should be considered non-compliant with the Aarhus Convention.
RETÓRICA DO ARGUMENTO DA OBJETIVIDADE DECISÓRIA NO STF NAS ADPF’S 701, 810 E 811
Authors: Falcão Pablo Ricardo de Lima 
Published: August 2023

Trata-se da análise retórica de argumentos no processo jurídico de decisão. Problema de pesquisa: quais são as limitações persuasivas do argumento da objetividade decisória no STF? Objetivo geral: desconstruir as cadeias argumentativas que justificaram as decisões judiciais nas ADPF’s 701, 810 e 811 a fim de descrever os mecanismos estratégicos de ocultação das limitações de controle da subjetividade judicante proposta tanto pela doutrina jurídica, quanto pela legislação vigente. Objetivos específicos: contrapor os votos (vencedor e vencido) e descrever como um deles angariou maiores graus de eficácia e legitimidade. Abordagem metodológica: metódica desestruturante. Técnica de pesquisa: bibliográfica. Apresentação dos resultados: quali-quantitativa. Resultado: Os mecanismos discursivos de ocultação da subjetividade judicante não passam despercebidos à metódica desestruturante, contudo, surtem efeitos práticos significativos quando fazem parte de um discurso estrategicamente mais eficaz.
Palavras-Chave: Retórica. Argumentação. Objetividade. STF. ADPF.
Transcatheter Aortic Valve Implantation in Heart Failure Patients with Non-Severe Aortic Valve Stenosis
Authors: Elkammash Amr 
Published: August 2023

Introduction: aortic stenosis (AS) increases the afterload on the left ventricle, leading to structural changes in the heart muscle and gradual progression to heart failure (HF). The clinical guidelines recommend aortic valve replacement (surgical or transcatheter) in patients with HF and severe AS. The evidence on the benefits of Transcatheter aortic valve implantation (TAVI) for patients with less-than-severe AS and HF is still controversial and inconclusive. Methods: the literature was systematically searched on three different scientific databases (PUBMED, Google Scholar, EMBASE) using different combinations of search words (heart failure, non-severe aortic stenosis, less-than-severe aortic stenosis, mild to moderate aortic stenosis, TAVI, TAVR). Results: in heart failure patients, observational studies showed a significant reduction in mortality using TAVI to manage non-severe aortic stenosis compared to medical treatment. However, evidence from randomized controlled trials is still lacking. Conclusion:HF increases the surgical risk of AS patients; therefore, TAVI represents a safer option. The preliminary results indicated the benefit of TAVI in managing AS in HF patients, even if the AS did not reach the severe stage. Doi: 10.28991/SciMedJ-2022-04-04-05 Full Text: PDF
Upaya Pengelolaan Diabetes Mellitus Tipe 2 dengan Pendekatan Pelayanan Kedokteran Keluarga
Authors: Siregar Wina Yunida M , Ikhsan Ridhalul , Ikhsan Maulana , Dewi Rahmia , Muna Zurratul , Zara Noviana , Debbyousha Maulina 
Published: August 2023

Pasien perempuan berusia 30 tahun datang dengan keluhan kaki kesemutan yang dirasakan dalam 1 bulan ini dan memberat dalam 2 minggu ini. Pasien juga mengeluhkan gatal-gatal di seluruh tubuh sejak 2 minggu ini. Pasien merasa jika terjadi luka lama sembuhnya. Pasien merasa sering buang air kecil pada malam hari. Pasien juga merasa sering lapar dan sering haus. Pemerikssaan kadar glukosa darah sewaktu pada pasien didapatkan 353 mg/dl. Perhitungan index massa tubuh didapatkan 21,7 kg/m2 (normal). Data primer diperoleh melalui anamnesis dan pemeriksaan fisik dengan melakukan kunjungan rumah. Penilaian dilakukan berdasarkan diagnosis holistik awal, proses, dan akhir kunjungan. Intervensi yang dilakukan diantaranya adalah edukasi mengenai pentingnya mengonsumsi obat secara teratur untuk mengontrol kadar gula darah dan komplikasi yang dapat terjadi. Pasien juga diedukasi mengenai pola makan, edukasi untuk melakukan aktivitas fisik dan olahraga.