bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eksplorasi, Identifikasi, dan Bioesai Jamur Entomopatogen terhadap Spodoptera frugiperda dari Kabupaten Purbalingga
Authors: Suroto Agus , Soesanto Loekas , Bahrudin Muhamad 
Published: September 2023

The goals of this study were to explore and identify entomopathogenic fungi, as well as determine the most effective application techniques to control S. frugiperda from exploration of infected Spodoptera frugiperda larvae in Purbalingga Regency. The research was carried out at the Plant Protection Laboratory, Faculty of Agriculture, Jenderal Soedirman University, from January to May 2022. Samples were collected by purposive random method. The study used a Complete Randomized Design, consisting of two factors, namely the type of entomopathogenic fungus and the application technique, with 9 combinations and 3 replications. Observed variables include mortality, feeding activity, growth, and reproduction of larvae. The results showed that (1) the results of exploration of entomopathogenic fungi were from the genus Metarhizium sp. and Penicillium sp. (2) single treatment of Metarhizium sp. is more effective than Penicillium sp. in killing S. frugiperda larvae. Fungi Metarhizium sp. and Penicillium sp. decreased feeding activity, length of three-instar larval period, and number of eggs, respectively 24.99 and 15.99%, 4.71 and 2.46%, 9.18 and 8.04% against controls. (3) single treatment of feed soaking method decreased mortality by 55.18% than other methods. Spraying the larval body decreased mortality by 44.84% compared to other methods. The method of application did not affect the feeding, growth and fecundity activity of larvae. (4) The combined treatment of Metarhizium sp., spraying the larval body, and soaking feed had a mortality percentage of 60%. Interaction treatment of the fungus Metarhizium sp. and the method of application lowered the feed power by 16%. The decrease in the period of three instar larvae to pupae and the largest number of eggs in the combination treatment of Metarhizium sp. and spraying of larval bodies was 6.34% and 11.20% respectively compared to controls.

Keywords: bioassay, entomopathogenic fungi, Spodoptera frugiperda, Purbalingga
Evaluasi Arachis pintoi sebagai Biomulsa dalam Memperbaiki Kesuburan Tanah pada Pertanaman Jagung di Kemiringan Lahan yang Berbeda
Authors: Sumiahadi Ade , Chozin Muhamad Ahmad , Guntoro Dwi 
Published: September 2023

Expanding agricultural land by using sloping dry land can be detrimental to the environment due to soil erosion and degradation. However, cover crops can be one of the technologies applied to reduce these risks. Arachis pintoi is one of cover crops that can be used as bio mulch on agricultural land. The study aimed to evaluate the effect of A. pintoi bio mulch on soil nutrient contents and maize plant growth at different slopes. A nested randomized block design was used in the study. Two levels of land used as the main factor and the type of mulch consisting of five levels (without mulch with weeding, without mulch without weeding, silver-black plastic mulch, straw mulch, and A. pintoi bio mulch) were used as the second factor. The results showed that A. pintoi bio mulch significantly increased the P content of the soil and could potentially increase several other macronutrients, especially C-organic, N, and Ca. The use of A. pintoi bio mulch with a cover technique that was left to cover the entire soil surface suppressed the growth and yield of maize plants compared to the control treatment.

Keywords: cover crops, mulch, ornamental peanut, soil fertility, rice straw
Effectiveness of Hydrilla verticillata as Bioaccumulator Against Soil Contamination in Flooded Rice Cultivation
Authors: Ferdiansah Iqbal Bayu , Ubaidillah Mohammad 
Published: September 2023

Soil pollution can occur due to agricultural waste, one of which is the excessive use of pesticides. Contaminants that are often found are heavy metal of copper (Cu). Rice plants will absorb and store heavy metal elements in polluted soil and waters, and these heavy metals will undergo a process of bioaccumulation in plants that affect plant growth. Efforts to deal with heavy metal contaminants have been carried out. In its application, plants such as hydrilla plant (Hydrilla verticillata) can be used to reduce pollution in the environment. This study aims to determine the effectiveness of using hydrilla plants in reducing heavy metal pollutant copper in flooded rice cultivation. This research was conducted from May-November 2022 at the Agrotechnology Greenhouse, and for laboratory testing it was carried out at the CDAST Laboratory, University of Jember. This research was conducted using a completely randomized design consisting of one factor with four replications. Giving hydrilla did not significantly affect the morphology of rice plants but had a significant effect on the increasing levels of chlorophyll. The concentration of copper in rice plants decreased after treatment with hydrilla plants compared to negative controls without hydrilla plants. In this study, it can be concluded that the use of hydrilla was able to reduce the levels of copper metal present in rice plants and did not affect the growth of rice plants morphologically.

Keywords: copper, hydrilla, paddy, soil contamination
La disrupción tecnológica en el ámbito sanitario europeo: implicaciones de la telemedicina pública en la protección de datos de los pacientes
Authors: Rodríguez Ayuso Juan Francisco 
Published: September 2023

El presente trabajo de investigación indaga en torno a la noción y naturaleza jurídica de la telemedicina como servicio de intermediación en línea que, merced a la configuración de aplicaciones móviles implementadas por plataformas digitales, posibilita la prestación telemática del derecho de los pacientes a ser atendidos sanitariamente. Fruto de este análisis, se propone una aproximación al marco normativo aplicable, sobre la base de la necesaria distinción entre el servicio médico prestado y el medio virtual a través del cual se presta, fundamental para indagar en el entramado legal y la ferviente multiplicación de reglas orientadas a disciplinar figuras, como esta, surgidas al amparo de las TIC. Finalmente, se aborda una cuestión no menos relevante: la implicación que este tratamiento masivo de información altamente sensible tiene en el derecho fundamental de los interesados a la protección de sus datos, siendo preciso atender a aspectos tan importantes como la propia noción de datos de salud, la regla que prohíbe su tratamiento, la relevancia que presenta el consentimiento del paciente como elemento habilitador del mismo, los fines perseguidos por las apps de eHealth o las medidas a adoptar para garantizar una seguridad acorde al elevado riesgo que conllevan este tipo de operaciones.
Recibido: 22 febrero 2023Aceptado: 18 mayo 2023
Camino hacia la integración de Ucrania en la UE: la política cultural europea
Authors: Perales García José Luis 
Published: September 2023

Una de las consecuencias inmediatas de la guerra de Rusia contra Ucrania ha sido el reconocimiento taxativo de que Ucrania «forma parte de la familia europea». El inicio de este conflicto puede retrotraerse, sin embargo, hasta marzo de 2014. Poco después de las protestas de Euromaidán, la UE firmó en 2014 con Ucrania el Acuerdo de Asociación que ha servido para enmarcar la política de vecindad con este país y posibilitar sus reformas. Tras el impacto de la pandemia del COVID-19, la invasión rusa de Ucrania a gran escala de 2022 ha supuesto el despertar de una UE geopolítica más asertiva en un mundo más inestable. Como consecuencia de ello, la UE ha relanzado las negociaciones de adhesión con los países de los Balcanes Orientales y ha admitido como candidatos a Ucrania y Moldavia. En este contexto ha nacido la Comunidad Política Europea, que podría servir de antesala a la adhesión de estos países a la UE. Sin embargo, sin un final de la guerra en el horizonte, Ucrania podría avanzar en el camino hacia la plena integración en la UE negociando el capítulo dedicado a la cultura entendiendo esta en sentido amplio, y beneficiándose de los programas e iniciativas comunitarios como otros Estados miembros por medio de una integración diferenciada.
Recibido: 20 abril 2023Aceptado: 7 junio 2023
Multi-objective scheduling in dynamic of household paper workshop considering energy consumption in production process
Authors: Zhang Zhenya , He Xiuli , Man Yi , He Zhenglei 
Published: September 2023

Aim: The uncertainty and complexity of the production process of household paper are growing sharply in modern factories. Due to the influence of rising energy costs and environmental policies, the demand for reducing production costs and energy consumption is also increasing. Therefore, it is studied that the dynamic shop scheduling problem of household paper production considering simultaneously the cost with energy consumption.
Methods: A mathematical model of the multi-objective and multi-constraint household paper scheduling problem is established first. The multi-objective scheduling process is transformed into a multi-agent Markov game process by assigning each objective to each agent. Upon which, a multi-agent game model is constructed for the household paper scheduling problem based on deep reinforcement learning; it is a proposed D3QN algorithm and Nash equilibrium strategy, and the state characteristics and action selection space are proposed according to the characteristics of the household paper production. The model performance has been verified by the actual production data.
Results: Results show that the proposed method not only achieves better performance than traditional scheduling methods but also persists in its advantages even when the configuration of the manufacturing system changes.
Conclusion: Multi-agent deep reinforcement learning in the Markov game has a good prospect in solving multi-objective dynamic scheduling problems for household paper production.
Comparison of microalgal hydrochar and pyrochar: production, physicochemical properties, and environmental application
Authors: Park Chaerin , Kim Eun Jung 
Published: September 2023

Abstract
Microalgal biomass has been considered the third-generation biofuel production feedstock, but microalgae-derived biochar still needs to be thoroughly understood. This study aims to evaluate the production and physicochemical properties of microalgae-derived hydrochar by comparison with pyrochar for environmental applications. Microalgal biochar was produced with commercially available Chlorella Vulgaris microalgae using hydrothermal carbonization (HTC) and dry thermal carbonization (DTC) processes under various temperature conditions. Pyrochar presented higher pH, ash contents, porosity, and surface area than hydrochar. Hydrochar gave more oxygen-containing functional groups on the surface and higher lead adsorption than pyrochar, making the microalgal hydrochar applicable in soil amendment and various environmental remediation. HTC could be an economically feasible thermochemical process for microalgal biochar production. It can produce hydrochar with high production yield from wet microalgae at low temperatures without a drying process.
Direct and indirect association of domestic violence against women and severe maternal morbidity: a case control study
Authors: Sahebi Mahdieh , Abdollahpour Sedigheh , Sadeghi Masoumeh , Miri Hamid Heidarian 
Published: September 2023

Abstract
Introduction
Along with the reduction in maternal mortality, severe maternal morbidity (SMM) is getting more popular for the evaluation of maternal health programs. To prevent severe maternal morbidity we should know the risk factors which are similar to maternal mortality. the goal of this study is the investigation of direct association of domestic violence and indirect association of this exposure through pregnancy, delivery and neonatal risk factors with severe maternal morbidity as outcome.
Method
The target population of this case-control study is all women who gave birth in the hospitals of Torbat Heidarieh university of medical science in 2017(1397).
123 mothers with severe maternal morbidity (SMM) according to WHO criteria were selected as cases and 127 mothers who did not have WHO criteria were selected as a control group. Data were analyzed by STATA14 and mediation packages with the counterfactual approach.
Result
The odds ratio of pure direct effect for physical violence through pregnancy and neonatal risk factor are 2.26 and 2.29, respectively. The odds ratio of social violence through pregnancy, delivery and neonatal risk factors are 2.54, 267, and 2.57 and for economicalal violence through neonatal risk factors is 1.99. also the interaction between physical and social violence and pregnancy risk factors increase the risk of severe maternal morbidity by 394.6% and 360%, respectively.
conclusion
Domestic violence against women has direct association with SMM which has a significant effect on outcome as exposure. Physical and social violence have significant interaction with SMM. It is recommended to consider domestic violence screening as one of the effective interventions to prevent SMM and to improve the health of mothers by applying control strategies.
On the Time-Frequency Dynamics of Growth Cycles in Brazil
Authors: Matos Paulo , Alves Douglas , Monteiro Valdeir 
Published: September 2023

Abstract
We add to the empirical literature on growth, by addressing instrumentalized co-movements between the quarterly variation of real GDP per capita versus fiscal, monetary, and credit variables in Brazil. We use partial wavelet coherency to analyze time-frequency growth dependency on macro variables: net debt to GDP, primary balance to GDP, inflation, SELIC rate, household, and enterprise credit to GDP. We also use partial phase difference and partial gain to identify and measure the lead-lag relationship between growth and these macro variables. We provide a set of new stylized facts about the recent history of growth in Brazil over the period from 2004 and 2022, a period marked by three recessions. To summarize, in periods of expansion, primary balance cycles lead in-phase growth cycles, while inflationary and household credit cycles use to lead out-of-phase growth cycles. During recessions, we find a relevant positive role played by the enterprise credit, and a negative leadership of SELIC on economic growth cycle.
JEL classification: C02, O42, H60
Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer
Authors: Simpkins Fiona , Kinose Yasuto , Xu Haineng , Kim Hyoung , Kumar Sushil , Shan Xiaoyin , Geroge Erin , Wang Xiaolei , Medvedev Sergey , Ferman Benjamin , Gitto Sarah , Whicker Margaret , D.Andrea Kurt , Wubbenhorst Bradley , Hallberg Dorothy , O'Connor Mark , Schwartz Lauren , Hwang Wei-Ting , Nathanson Katherine , Mills Gordon , Velculescu Victor , Wang Tian-Li , Brown Eric , Drapkin Ronny 
Published: September 2023

Abstract
ARID1A, an epigenetic tumor suppressor, is the most common gene mutation in clear-cell ovarian cancers (CCOCs). CCOCs are often resistant to standard chemotherapy and lack effective therapies. We hypothesized that ARID1A loss would increase CCOC cell dependency on chromatin remodeling and DNA repair pathways for survival. We demonstrate that combining BRD4 inhibitor (BRD4i) with DNA damage response inhibitors (ATR or WEE1 inhibitors; e.g. BRD4i-ATRi) was synergistic at low doses leading to decreased survival, and colony formation in CCOC in an ARID1A dependent manner. BRD4i-ATRi caused significant tumor regression and increased overall survival in ARID1AMUT but not ARID1AWT patient-derived xenografts. Combination BRD4i-ATRi significantly increased γH2AX, and decreased RAD51 foci and BRCA1 expression, suggesting decreased ability to repair DNA double-strand-breaks (DSBs) by homologous-recombination in ARID1AMUT cells, and these effects were greater than monotherapies. These studies demonstrate BRD4i-ATRi is an effective treatment strategy that capitalizes on synthetic lethality with ARID1A loss in CCOC.
Lymphatic drainage patterns of malignant skin tumors in the head and neck region: a single-center retrospective study
Authors: Nishio Takuya , Maeda Taku , Ishikawa Kosuke , Murao Naoki , Fuyama Kanako , Yamamoto Yuhei , Hayashi Toshihiko 
Published: September 2023

Abstract
Background
This study aimed to clarify the relationship between primary site and lymphatic drainage pattern for malignant skin tumors in the head and neck region. Malignant melanoma and squamous cell carcinoma in the head and neck region are known to have poor prognosis because of lymph node metastasis. Nevertheless, numerous aspects of lymphatic drainage patterns remain elusive.
Methods
We statistically analyzed data of 47 patients with malignant skin tumors in the head and neck region. Information was collected on the patients' clinical characteristics, primary tumor site, and lymphatic drainage patterns.
Results
The parotid lymph nodes drained the greatest amount of lymph from skin tumors of the head and neck. Important lymphatic drainage pathways were the superficial cervical nodes for primary tumors in the buccal/nasal region, level IA and level IB nodes for primary tumors in the lip region, the occipital nodes, posterior auricular nodes, and level VA nodes in the parietal/occipital region, and the preauricular nodes in the auricular region.
Conclusion
These findings have considerable significance in terms of understanding lymphatic drainage patterns for malignant skin tumors in the head and neck and may be useful for clinical decision-making and when planning treatment. Further research and clinical applications are expected to contribute to an improved prognosis in patients with cutaneous head and neck malignancies.
Jordanian Population Knowledge, Attitude and Practices on the Uses of Antidiabetics for Weight Loss Purposes: A Cross Sectional Study
Authors: Abutaima Rana , Barakat Muna , Sawan Hana Abu , ALomari Shatha , Mhaidat Nizar 
Published: September 2023

Abstract
Background Obesity became a recent pandemic, especially, during the Corona Virus Pandemic of 2019 (COVID-19) lockdown. Therefore, people started to adopt effortless methods to lose weight such as certain antidiabetic medications.Objectives To evaluate Jordanian population knowledge, attitude and practices towards the use of antidiabetic medications such as (Ozempic®), (Saxenda®), (Mounjaro®) and (Glucophage®) for weight loss.Method A self-administered validated online questionnaire was developed and disseminated to public. Data were extracted to examine descriptive statistics. Linear regression was performed to evaluate predictors of knowledge and attitude. A P-value ≤ 0.05 was chosen to indicate statistical significance.Results Total of 389 responses were analyzed, 65.6% females, 54.2% married, 78.1% living in the center of Jordan, 35.5% overweight and 26.5% have > 1000 Jordanian Dinars (JOD) monthly income. 57% think that antidiabetics could be used for weight loss. 47.27%, 44.55%, 68.18% recognized (Ozempic®), (Saxenda®), (Mounjaro®) and (Glucophage®) use for weight loss, respectively and 12.3% of participants used medications to lose weight. Neutral attitude was observed. Gender and body mass index (BMI) were significant predictors of knowledge (P < 0.001, P = 0.002, respectively).Conclusion Use of (Ozempic®), (Saxenda®) and other antidiabetics to lose weight become a common practice. The results of this study suggests supervising prescription and dispensing to avoid misuse, especially, in people who are contraindicated to use them.
A method to enhance the nonlinear magnetic plucking for vibration energy harvesters
Authors: Rosso Michele , Cuccurullo Simone , Perli Filippo Pietro , Maspero Federico , Corigliano Alberto , Ardito Raffaele 
Published: September 2023

Abstract
In this work, a technique to improve the magnetic plucking phenomenon for frequency up-converting piezoelectric energy harvesters is presented. The technique involves using shielded magnets with Neodymium-iron-boron alloy polarized in the opposite direction on a main magnet. The phenomenon is investigated both at the computational and the experimental level. Subsequently, simulations on a mesoscale piezoelectric energy harvester are presented which demonstrate a gain of 17 times if the magnets are shielded in comparison with the classical plucking (i.e. without shielding). The technique finds useful applications and benefits in the field of low-speed and low-frequency vibration energy harvesting, such as in actuation and sensing.
Effect of Gravity Orientation on Flickering Characteristics of Premixed Conical Flame
Authors: Qian Chenghao , Yang Yao , Wang Gaofeng , Kirkunova Anastasia , Hu Keqi 
Published: September 2023

Abstract
Experimental and numerical simulation methods were employed to investigate the effect of gravity orientation on the dynamics of premixed conical flames. The study focused on a typical propane-air flame established on a Bunsen burner. Experiments and simulations were conducted under normal gravity (+ g), reverse gravity (-g), and transverse gravity (⊥g). In the initial phase of the research, the time-averaged shape of the flame under these gravity orientations was examined using flame chemiluminescence imaging. Particle Image Velocimetry (PIV) experiments and Direct Numerical Simulation (DNS) were performed to capture transient information, allowing for the visualization of the flame's flickering motion. The Dynamic Mode Decomposition (DMD) method was applied to analyze the velocity results, providing further insights into the mode and phase characteristics of flame dynamics. Additionally, the frequencies of flame flickering were determined through heat release signal experiments, revealing the relationship between gravity direction and flickering frequency. The study also validated a well-known empirical correlation for the + g case and attempted to adopt a formula for the ⊥g case.
Clinical features analysis of 75 deceased donors maintained in ICU
Authors: YAO Zhiyuan , LIU Yu , ZHAN Liying , QIU Tao , LI Guang , CHEN Zhongbao , FANG Xiaoyu , LIU Zhou , WU Wei , LIAO Zhaomin , XIA Wenfang 
Published: September 2023

Abstract
Objective
To summarize and analyze the integrated management program of 75 deceased donors maintained in ICU of our hospital, so as to promote the development of organ transplantation.
Methods
The data deceased donors maintained in ICU of our hospital from June 2020 to January 2022 were collected. The basic data, laboratory examination results, disease distribution and maintenance measures were retrospectively studied.
Results
75 patients were included, with a sex ratio (M/F) of 90.67% vs 9.33%, a median age of 55, a median ICU length of 4 days. Donors with higher APACHE II scores tended to enter the donation process faster (P=0.001). The primary disease of donors was mainly cerebral hemorrhage (53, 70.67%). 53 pathogens were detected in 58 patients (infection rate: 77.33%), mainly bacteria (42, 79.25%, Gram-negative mainly), Klebsiella pneumoniae, Acinetobacter baumannii and Escherichia coli were the most detected. 96.00% (72/75) donors successfully completed donation, mainly donation after cardiac death (65, 86.67%). 229 large organs and tissues were obtained from 72 donors, with an acquisition ratio of 1:3.14. The acquisition ratio of donors of different ages was statistically different (P<0.001). The overall organ utilization rate was 96.51% (221/229), and the kidney utilization rate in our hospital was 95.14% (137/144).
Conclusion
ICU plays an irreplaceable role in organ transplantation. ICU staffs familiarize the integrated management program of deceased donors, which is helpful to promote the development of organ transplantation.