bluuebunny/crossref_metadata_2025_split huggingface dataset:
Energy gap of topological surface states in proximity to a magnetic insulator
Authors: Wang Jiashu , Wang Tianyi , Ozerov Mykhaylo , Zhang Zhan , Bermejo-Ortiz Joaquin , Bac Seul-Ki , Trinh Hoai , Zhukovskyi Maksym , Orlova Tatyana , Ambaye Haile , Keum Jong , de Vaulchier Louis-Anne , Guldner Yves , Smirnov Dmitry , Lauter Valeria , Liu Xinyu , Assaf Badih A. 
Published: August 2023

AbstractTopological surface-states can acquire an energy gap when time-reversal symmetry is broken by interfacing with a magnetic insulator. This gap has yet to be measured. Such topological-magnetic insulator heterostructures can host a quantized anomalous Hall effect and can allow the control of the magnetic state of the insulator in a spintronic device. In this work, we observe the energy gap of topological surface-states in proximity to a magnetic insulator using magnetooptical Landau level spectroscopy. We measure Pb1-xSnxSe–EuSe heterostructures grown by molecular beam epitaxy exhibiting a record mobility and low Fermi energy. Through temperature dependent measurements and theoretical calculations, we show this gap is likely due to quantum confinement and conclude that the magnetic proximity effect is weak in this system. This weakness is disadvantageous for the realization of the quantum anomalous Hall effect, but favorable for spintronic devices which require the preservation of spin-momentum locking at the Fermi level.
SiO outflows in the most luminous and massive protostellar sources of the southern sky
Authors: Guerra-Varas N. , Merello M. , Bronfman L. , Duronea N. , Elia D. , Finger R. , Mendoza E. 
Published: August 2023

Context.High-mass star formation is far less understood than low-mass star formation. It entails the ejection of matter through molecular outflows, which disturbs the protostellar clump. Studying these outflows and the shocked gas caused by them is the key to a better understanding of this process.Aims.The present study aims to characterise the behaviour of molecular outflows in the most massive protostellar sources in the southern Galaxy by looking for evolutionary trends and associating the presence of shocked gas with outflow activity.Methods.We present APEX SEPIA180 (Band 5) observations (beamwidth ~36″) of SiO(4-3) molecular outflow candidates towards a well-selected sample of 32 luminous and dense clumps, which are candidates for harbouring hot molecular cores. We study the emission of the SiO(4-3) line, which is an unambiguous tracer of shocked gas, and recent and active outflow activity, as well as the HCO+(2-1) and H13CO+(2-1) lines.Results.Results show that 78% of our sample (25 sources) present SiO emission, revealing the presence of shocked gas. Nine of these sources are also found to have wings in the HCO+(2-1) line, indicating outflow activity. The SiO emission of these nine sources is generally more intense (Ta> 1 K) and wider (~61 km s−1FWZP) than the rest of the clumps with SiO detection (~42 km s−1FWZP), suggesting that the outflows in this group are faster and more energetic. This indicates that the shocked material gets dispersed as the core evolves and outflow activity decreases. Three positive linear correlations are found: a weak one (between the bolometric luminosity and outflow power) and two strong ones (one between the outflow power and the rate of matter expulsion and the other between the kinetic energy and outflow mass). These correlations suggest that more energetic outflows are able to mobilise more material. No correlation was found between the evolutionary stage indicator L/M and SiO outflow properties, supporting that molecular outflows happen throughout the whole high-mass star formation process.Conclusions.We conclude that sources with both SiO emission and HCO+wings and sources with only SiO emission are in an advanced stage of evolution in the high-mass star formation process, and there is no clear evolutionary difference between them. The former present more massive and more powerful SiO outflows than the latter. Therefore, looking for more outflow signatures such as HCO+wings could help identify more massive and active massive star-forming regions in samples of similarly evolved sources, and could also help identify sources with older outflow activity.
The socioeconomic status of adult children, intergenerational support, and the well-being of Chinese older adults
Authors: Zheng Zhenhua , Sun Ning , Yang Liu , Liu Wanting , Lu Yingchen , Chu Yusu , Chen Hong 
Published: August 2023

AbstractThe well-being of older adults is significantly influenced by their adult children, especially in countries with less developed welfare systems. We aim to examine the relationship between children’s intergenerational support, children’s socioeconomic status and the well-being of older adults, as well as compare the differences among various elderly groups. The data in our research are from the 2014 China Longitudinal Aging Social Survey. The survey covered 29 provinces, autonomous regions and municipalities in China with 9146 valid samples. We adopted descriptive statistical analysis and structural equation modeling to analyze the data, and the bootstrap method to test the mediating effects. Our results indicate that the children’s education level and intergenerational support do not significantly affect the well-being of all groups of older adults in China. However, the financial conditions of adult children have a significant and direct impact on the well-being of all groups of older adults. From one child to multiple children, the impact of children’s financial condition on the well-being of older adults is 0.360, 0.452, 0.412 in three urban groups and 0.496, 0.468, 0.443 in three rural groups, specifically. The influence of adult children’s financial conditions on the well-being of all groups of older adults in China is significant, surpassing that of children’s education level and intergenerational support. Moreover, the impact of children’s socioeconomic status on the well-being of older adults is primarily through direct effects, with minimal intervention from intergenerational support. For older adults in China, "whether my children are living well" is more important than "what they could give me".
Results of a 12-Month Randomized Controlled Trial Testing the Efficacy of the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) for People Post Stroke (GLB-CVA)
Authors: Driver Simon , McShan Evan , Swank Chad , Calhoun Stephanie , Douglas Megan , Suhalka Alexandria , Bennett Monica , Callender Librada , Ochoa Christa , Mukkamala Sridevi , Kramer Kaye 
Published: August 2023

Abstract

Background
Experience of stroke is associated with an increased risk for diabetes and metabolic syndrome, yet few interventions exist that have been tailored to the population’s unique needs.

Purpose
To examine adherence and efficacy of the Diabetes Prevention Program Group Lifestyle Balance program (DPP-GLB) modified for individuals post stroke (GLB-CVA) using a randomized controlled trial.

Methods
Adults (18–85 years of age), &gt;12 months post stroke, and body mass index ≥25 kg/m2 were included in this study. Sixty-five individuals were assigned to either the GLB-CVA intervention or a 6-month wait-list control. Participants completed the 12-month GLB-CVA intervention, with attendance and assessment of weight, anthropometric, biomarker, functional, and patient reported outcome data collected at baseline, 3, 6, and 12 months.

Results
High attendance (90%) and dietary and activity tracking (71%) suggest high adherence to the 12-month GLB-CVA. Six-month randomized controlled trial data indicate significant weight loss (p = .005) in the GLB-CVA group (7.4 ± 13.6 lbs, 3.65%) compared with the wait-list control (0.1 ± 10.1 lbs, 0%), and improvements in arm circumference (p = .04), high-density lipoprotein (HDL) cholesterol (p = .028), 8-year diabetes risk (p = .011), and pain interference (p &lt; .001). Combined 12-month data showed participants lost 10.1 ± 16.8 lbs (4.88%) and improved waist circumference (p = .001), HbA1c (3.6%), diastolic blood pressure (p &lt; .001), pain (p = .001), social participation (p = .025), and eating practices (p = .01) and habits (p &lt; .001).

Conclusions
Engagement in the GLB-CVA can result in weight loss and improved health for individuals who are overweight or obese following stroke. Future efforts should examine effectiveness in real-world settings and focus on knowledge translation efforts.
Difference of Systolic Blood Pressure Between Arms and Its Influencing Factors Among People Over 35 Years Old in China
Authors: Chen Xuelian , Wang Xin , Zhang Linfeng , Chen Zuo , Li Suning , Ma Mingyan , Zheng Congyi , Zhou Haoqi , Chen Lu , Cao Xue , Hu Jihong , Wang Zeng-wu 
Published: August 2023

Abstract

Background
To investigate the detection of the increase of interarm systolic pressure difference (IASBPD) in people aged ≥35 years in our country and its related factors.

Methods
Stratified multistage sampling method was used to randomly select 262 urban and rural residents from 31 provinces from 2012 to 2015. Further, simple random sampling method was used to select 16 cities and 17 rural residents from eastern, central, and western regions. A total of 34,121 subjects aged ≥35 years were analyzed after removing the missing information. Data were collected by questionnaire, and blood pressure in both arms was measured by ankle–brachial index meter. All data were analyzed by SPSS 23.0 software. Continuous data were expressed as mean ± SD. Comparison between groups was performed using t-test if it was normal distribution, and rank-sum test if it was not. Categorical data were expressed as frequency sum rate or constituent ratio, χ2 test was used for comparison of various rates and constituent ratio, and rank-sum test was used for rank data. Multivariate logistic regression was used to analyze the influencing factors of IASBPD increase.

Results
The detection rates of IASBPD ≥10 and ≥15 mm Hg were 16.31% and 7.55%, respectively. The detection rate of IASBPD ≥10 mm Hg in males was higher than that in females (P &lt; 0.05). Multivariate logistic regression showed that age, family history of hypertension, low HDL-C, hypertension, and abdominal obesity were risk factors for IASBPD ≥10 and 15 mm Hg (all P &lt; 0.05).

Conclusions
The detection rates of IASBPD ≥10 and 15 mm Hg are 16.31% and 7.55%, respectively, in Chinese ≥35 years old people, and age, low HDL-C emia, family history of hypertension, hypertension, and abdominal obesity are the influencing factors of large differences in interarm blood pressure.
Consensus-defined sarcopenia predicts adverse outcomes after elective abdominal surgery: meta-analysis
Authors: Park Brittany , Bhat Sameer , Xia Weisi , Barazanchi Ahmed W H , Frampton Christopher , Hill Andrew G , MacCormick Andrew D 
Published: August 2023

Abstract

Background
Sarcopenia refers to the progressive age- or pathology-associated loss of skeletal muscle. When measured radiologically as reduced muscle mass, sarcopenia has been shown to independently predict morbidity and mortality after elective abdominal surgery. However, the European Working Group on Sarcopenia in Older People (EWGSOP) recently updated their sarcopenia definition, emphasizing both low muscle ‘strength’ and ‘mass’. The aim of this systematic review and meta-analysis was to determine the prognostic impact of this updated consensus definition of sarcopenia after elective abdominal surgery.

Methods
MEDLINE, Embase, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL) databases were systematically searched for studies comparing prognostic outcomes between sarcopenic versus non-sarcopenic adults after elective abdominal surgery from inception to 15 June 2022. The primary outcomes were postoperative morbidity and mortality. Sensitivity analyses adjusting for confounding patient factors were also performed. Methodological quality assessment of studies was performed independently by two authors using the QUality in Prognosis Studies (QUIPS) tool.

Results
Twenty articles with 5421 patients (1059 sarcopenic and 4362 non-sarcopenic) were included. Sarcopenic patients were at significantly greater risk of incurring postoperative complications, despite adjusted multivariate analysis (adjusted OR 1.56, 95 per cent c.i. 1.39 to 1.76). Sarcopenic patients also had significantly higher rates of in-hospital (OR 7.62, 95 per cent c.i. 2.86 to 20.34), 30-day (OR 3.84, 95 per cent c.i. 1.27 to 11.64), and 90-day (OR 3.73, 95 per cent c.i. 1.19 to 11.70) mortality. Sarcopenia was an independent risk factor for poorer overall survival in multivariate Cox regression analysis (adjusted HR 1.28, 95 per cent c.i. 1.13 to 1.44).

Conclusion
Consensus-defined sarcopenia provides important prognostic information after elective abdominal surgery and can be appropriately measured in the preoperative setting. Development of targeted exercise-based interventions that minimize sarcopenia may improve outcomes for patients who are undergoing elective abdominal surgery.
Homomeric interactions of the MPZ Ig domain and their relation to Charcot-Marie-Tooth disease
Authors: Ptak Christopher P , Peterson Tabitha A , Hopkins Jesse B , Ahern Christopher A , Shy Michael E , Piper Robert C 
Published: August 2023

Abstract
Mutations in MPZ (myelin protein zero) can cause demyelinating early-onset Charcot-Marie-Tooth type 1B disease or later onset type 2I/J disease characterized by axonal degeneration, reflecting the diverse roles of MPZ in Schwann cells. MPZ holds apposing membranes of the myelin sheath together, with the adhesion role fulfilled by its extracellular immunoglobulin-like domain (IgMPZ), which oligomerizes.
Models for how the IgMPZ might form oligomeric assemblies has been extrapolated from a protein crystal structure in which individual rat IgMPZ subunits are packed together under artificial conditions, forming three weak interfaces. One interface organizes the IgMPZ into tetramers, a second ‘dimer’ interface links tetramers together across the intraperiod line, and a third hydrophobic interface that mediates binding to lipid bilayers or the same hydrophobic surface on another IgMPZ domain. Presently, there are no data confirming whether the proposed IgMPZ interfaces actually mediate oligomerization in solution, whether they are required for the adhesion activity of MPZ, whether they are important for myelination, or whether their loss results in disease.
We performed nuclear magnetic resonance spectroscopy and small angle X-ray scattering analysis of wild-type IgMPZ as well as mutant forms with amino acid substitutions designed to interrupt its presumptive oligomerization interfaces. Here, we confirm the interface that mediates IgMPZ tetramerization, but find that dimerization is mediated by a distinct interface that has yet to be identified. We next correlated different types of Charcot-Marie-Tooth disease symptoms to subregions within IgMPZ tetramers. Variants causing axonal late-onset disease (CMT2I/J) map to surface residues of IgMPZ proximal to the transmembrane domain. Variants causing early-onset demyelinating disease (CMT1B) segregate into two groups: one is described by variants that disrupt the stability of the Ig-fold itself and are largely located within the core of the IgMPZ domain; whereas another describes a region on the surface of IgMPZ tetramers, accessible to protein interactions. Computational docking studies predict that this latter disease-relevant subregion may potentially mediate dimerization of IgMPZ tetramers.
Effects of heat wave on development, reproduction, and morph differentiation of Aphis glycines (Hemiptera: Aphididae)
Authors: Liu Dailin , Wu Cirui , Wang Qi , Liu Donghao , Tian Zhenqi , Liu Jian 
Published: August 2023

Abstract
As global warming intensifies, heat waves occur frequently in the summer and autumn in Heilongjiang Province, northeast China. The soybean aphid, Aphis glycines Matsumura, is an important pest of soybean in the region, which faces great survival pressure due to high temperature. In this study, A. glycines fed soybean (AgFS) and wild soybean (AgFW) were exposed to diurnal 35 °C for 7 days begin at different developmental stages, and the development, reproduction, and morph differentiation were studied. When AgFS were exposed to heat waves from the second stadium to the adult stage, they performed worse in adult lifespan and fecundity than the control. When AgFW were exposed to heat waves begin at different developmental stages, the adult lifespan and reproduction period were shortened and reproduction ability decreased. When exposed to heat waves, the adult fecundity and intrinsic rate of increase in AgFW were lower than those of AgFS. Lower proportion of males were deposited on day 13, when AgFS and AgFW were exposed to diurnal 35 °C begin at different developmental stages. The results showed that heat waves lasting for 7 days were likely to be useful in the management of A. glycines, which reduced adult reproduction ability and male differentiation proportion in the offspring and significantly affected AgFW compared to AgFS. These results are important for predicting the dynamics of A. glycines in Heilongjiang, northeast China, where the local environmental temperature is increasing and heat waves occur frequently.
Two severe complications post-percutaneous intramyocardial septal radiofrequency ablation in a patient with failed alcohol septal ablation: pulseless electrical activity cardiac arrest and pericardial tamponade—a case report
Authors: Shu Tian , Shen Caijie , Chen Xiaomin , Yu Fei 
Published: August 2023

Abstract

Background
Alcohol septal ablation (ASA) can be recommended for patients with drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). Recently, percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) was reported as a safe and effective treatment for HOCM.

Case summary
We present a case report of pulseless electrical activity (PEA), cardiac arrest, and pericardial tamponade occurring post-PIMSRA. We performed PIMSRA for the patient with HOCM after failed ASA. Two hours post-PIMSRA, transthoracic echocardiography (TTE) revealed that the hypokinetic basal intraventricular septal (IVS) thickness increased with aggravation of systolic anterior motion of the mitral valve. After the occurrence of subsequent PEA cardiac arrest, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support was provided. With sinus rhythm restoration and blood pressure stabilization after ECMO removal, the patient had pericardial tamponade on Day 3 post-PIMSRA. After excluding apparent myocardial perforation and draining haemorrhagic effusion under TTE guidance, her symptoms and haemodynamic status improved. She was asymptomatic at her one-year follow-up. The left ventricular outflow tract gradient (LVOTG) at rest and the thickness of the basal IVS reduced to 5 mmHg and 12 mm, respectively.

Discussion
We assumed that the main causes of PEA cardiac arrest and pericardial tamponade in our case were ablation-related tissue oedema at the basal IVS and blood leakage possibly related to puncture haemorrhage, respectively. While waiting for myocardial oedema to resolve, ECMO was applied as a bridge-to-recovery therapeutic approach. Pericardiocentesis is a strategy for the emergency drainage of pericardial effusion. It is essential to distinguish life-threatening complications with TTE for management planning post-PIMSRA.
Transcoronary mapping using a guidewire during transcoronary ethanol ablation for ventricular tachycardia with a deep intramural substrate: a case report
Authors: Chiba Suguru , Abe Masami , Nakamura Kentaro , Uehara Hiroki 
Published: August 2023

Abstract

Background
Transcoronary ethanol ablation is effective in treating ventricular tachycardia (VT) in the deep myocardium. The selection of the target coronary artery plays an important role in the success of transcoronary ethanol ablation. Transcoronary mapping, using a guidewire, may be effective for identifying the target coronary artery.

Case summary
A 72-year-old man, who had undergone thrombolytic therapy for acute myocardial infarction 40 years ago, was admitted to the emergency department with a chief complaint of syncope. Five years ago, a cardiac resynchronization therapy defibrillator was implanted for a left bundle branch block (QRS duration 153 ms), with New York Heart Association Class Ⅲ and a left ventricular ejection fraction of 30%.
Due to VT, he experienced a critical deterioration in his vital parameters, leading to shock. The first VT ablation was performed on the 3rd day of hospitalization. Activation mapping showed that the earliest activation site was located in the mid-anterior septum of the left ventricle. Mapping from the endocardial surface showed no mid-diastolic potential around the VT. Radiofrequency catheter ablation therapy was performed at the targeted site, resulting in transient termination of VT. However, the VT showed recurrence the next day. A transcoronary ethanol ablation was performed on the 10th day of hospitalization. A 0.014 inch guidewire and microcatheter were advanced into the target coronary septal branch, and the myocardial septum was mapped. The guidewire-assisted transcoronary mapping showed a potential 43 ms ahead of QRS onset during VT. The coronary septal artery branch was considered the target artery, and 0.5 mL of ethanol was injected. No further VT was observed for 12 months after the transcoronary ethanol ablation.

Discussion
Transcoronary ethanol ablation is considered in cases where a deep intramural substrate is suspected or when early activation at the interventricular septum is identified. Guidewire-assisted transcoronary mapping allows mapping of VT with deep intramural substrates and may be useful in selecting target coronary arteries while performing transcoronary ethanol ablation.
OPERA: perception of information in patients with gastroenteropancreatic neuroendocrine tumors on lanreotide autogel
Authors: Hautefeuille Vincent , Walter Thomas , Do Cao Christine , Coriat Romain , Dominguez Sophie , Mineur Laurent , Cadiot Guillaume , Terrebonne Eric , Sobhani Iradj , Gueguen Delphine , Houchard Aude , Mouawad Charbel , Anota Amélie , Hammel Pascal 
Published: August 2023

Abstract

Importance
Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) can affect patient health-related quality of life (HRQoL). Appropriate information may improve their adherence to treatment and quality of life.

Objective
To evaluate the change in patient's perceptions of the level of information at lanreotide (LAN) treatment initiation for GEP-NETs vs after 6 months.

Design
OPERA (NCT03562091) was a prospective, longitudinal, noninterventional study.

Setting
Thirty-one centers in France specialized in the management of patients with NETs.

Intervention
Planned clinical visits at enrollment and end-of-study visits at month 6, with completion of the European Organisation for Research and Treatment of Cancer 25-item Quality of Life Questionnaire—Information Module (QLQ-INFO25) and 30-item Quality of Life Questionnaire—Core.

Main outcome
Absolute change in the patient's perception of the information between baseline and month 6, using the relevant domains of the QLQ-INFO25. Endpoints measured at baseline and month 6 for at least 1 of the 3 targeted QLQ-INFO25 dimensions of the primary endpoint.

Results
Ninety-three of the 115 patients enrolled completed ≥1 primary endpoint information dimension. Mean (SD) scores for the primary endpoint information dimensions were high at baseline (disease, 63.41 [20.71]; treatment, 58.85 [19.00]; supportive care, 26.53 [24.69]; maximum 100). There were no significant changes between baseline (98.34% CI) and 6 months (disease, −2.84 [−8.69, 3.01; P = .24]; treatment, −4.37 [−11.26, 2.52; P = .13]; supportive care, 0.46 [−6.78, 7.70; P = .88]), and in HRQoL between baseline and 6 months.

Conclusions and relevance
The lack of change in patient's perceptions of the disease, treatment, and supportive care information provided over the first 6 months of LAN treatment may suggest that physicians provided adequate information at the treatment initiation.