bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of autoclaving-time treatment on physicochemical, antioxidant properties and shelf-life prediction of Indonesian instant cassava leaves porridge
Authors: Iwansyah Ade Chandra , Desnilasari Dewi , Solichah Enny , Agustina Wawan 
Published: April 2023

This study investigated the effects of autoclaving-time treatment (0, 3, 5, and 7 minutes) on the physicochemical and antioxidant properties of Indonesian instant cassava porridge or rowe luwa. The shelf-life prediction of rowe luwa porridge also was determined. The rowe luwa porridge contained nutrition, such as moisture content (4.41%), fat (7.69%), protein (11.77%), carbohydrates (67.15%), energy (384.89 kcal), zinc (2.73 mg/100g), calcium (174.48 mg/100 g), and iron (2.9 mg/100 g). Furthermore, rowe luwa has a complete composition of essential amino acids the body needs. The rehydration time and pH of rowe luwa porridge showed the highest value on autoclaving for 3 minutes (AU3) and decreased with increasing autoclaving time (p < 0.05). The rehydration time was in line with the solubility and WAI values. The rowe luwa porridge with three minutes autoclave time treatment (AU3) also had the highest total phenolic contents (TP) and antioxidant activity (AOA), followed by AU0 > AU5> and AU7 (p < 0.05). Based on the FTIR spectra, the antioxidant of this instant cassava porridge might be
linked to phenolic chemicals. The shelf-life prediction of rowe luwa porridge with aluma packaging is 61 days or two months..
Keywords: autoclaving-time treatment; antioxidant; cassava leaves porridge; Moringa oleifera, shelf-life prediction
Perspectives of Youths on the Ethical Use of Artificial Intelligence in Health Care Research and Clinical Care
Authors: Thai Kelly , Tsiandoulas Kate H. , Stephenson Elizabeth A. , Menna-Dack Dolly , Zlotnik Shaul Randi , Anderson James A. , Shinewald Alexis R. , Ampofo Augustina , McCradden Melissa D. 
Published: May 2023

ImportanceUnderstanding the views and values of patients is of substantial importance to developing the ethical parameters of artificial intelligence (AI) use in medicine. Thus far, there is limited study on the views of children and youths. Their perspectives contribute meaningfully to the integration of AI in medicine.ObjectiveTo explore the moral attitudes and views of children and youths regarding research and clinical care involving health AI at the point of care.Design, Setting, and ParticipantsThis qualitative study recruited participants younger than 18 years during a 1-year period (October 2021 to March 2022) at a large urban pediatric hospital. A total of 44 individuals who were receiving or had previously received care at a hospital or rehabilitation clinic contacted the research team, but 15 were found to be ineligible. Of the 29 who consented to participate, 1 was lost to follow-up, resulting in 28 participants who completed the interview.ExposuresParticipants were interviewed using vignettes on 3 main themes: (1) health data research, (2) clinical AI trials, and (3) clinical use of AI.Main Outcomes and MeasuresThematic description of values surrounding health data research, interventional AI research, and clinical use of AI.ResultsThe 28 participants included 6 children (ages, 10-12 years) and 22 youths (ages, 13-17 years) (16 female, 10 male, and 3 trans/nonbinary/gender diverse). Mean (SD) age was 15 (2) years. Participants were highly engaged and quite knowledgeable about AI. They expressed a positive view of research intended to help others and had strong feelings about the uses of their health data for AI. Participants expressed appreciation for the vulnerability of potential participants in interventional AI trials and reinforced the importance of respect for their preferences regardless of their decisional capacity. A strong theme for the prospective use of clinical AI was the desire to maintain bedside interaction between the patient and their physician.Conclusions and RelevanceIn this study, children and youths reported generally positive views of AI, expressing strong interest and advocacy for their involvement in AI research and inclusion of their voices for shared decision-making with AI in clinical care. These findings suggest the need for more engagement of children and youths in health care AI research and integration.
Antiaggregation of NIR‐II Probe Regulated by Amphiphilic Polypeptide with High Contrast Brightness for Phototheranostics and Vascular Microscopic Imaging under 1064 nm Irradiation
Authors: Teng Changchang , Dang Huiping , Xu Yixuan , Yin Dalong , Yan Lifeng 
Published: April 2023

AbstractThanks to deep penetration and high resolution, the second near‐infrared window (NIR‐II, 1000–1700 nm) fluorescence (FL) imaging is expected to gain favor in clinical applications, including macroscopic imaging for cancer diagnosis and microangiography for vascular‐related disease diagnosis. Nevertheless, most NIR‐II fluorescent probes, especially cyanine, are highly susceptible to self‐quenching in the aggregated state, which severely limits their application in bioimaging. Here, the Br‐modified cyanine dye F4‐Br and the amphiphilic polypeptide poly(oligo[ethylene glycol]methacrylate)‐b‐poly(benzyl‐L‐aspartic acid) (POEGMA‐PBLA) are synthesized. By modulating the self‐assembly of F4‐Br and POEGMA‐PBLA to effectively inhibit the H‐aggregation of F4‐Br in aqueous solutions, nanoprobe F4‐Br@P17 with outstanding antiquenching capability is developed. This prominent feature allows it to perform vascular microscopic imaging with high spatiotemporal resolution and assess hemodynamic characteristics. F4‐Br@P17 nanoparticles (NPs) with good stability and satisfactory biocompatibility also enable high contrast brightness for NIR‐II FL imaging of tumors. Given the efficient enrichment at tumor sites and the promising photothermal conversion efficiency (43.5%), F4‐Br@P17 NPs successfully conduct photothermal therapy and exhibit superior antitumor efficiency under 1064 nm laser irradiation. These remarkable performances reveal the tremendous possibility of F4‐Br@P17 NPs for in vivo microscopic imaging and FL imaging‐guided photothermal therapy in the NIR‐II region.
Structure Design of Soft Magnetic Materials Using Electron‐Beam‐Based Additive Manufacturing
Authors: Yang Jing , Fu Zongwen , Körner Carolin 
Published: April 2023

AbstractFe93.5Si6.5(wt%) soft magnetic materials in toroidal shape are additively manufactured by means of electron beam powder bed fusion (PBF‐EB). Different hatching strategies are applied to realize specific patterns of molten material alternating with non‐molten powder particles. The specimens produced using different hatching strategies show identical relative densities but various structural features resulting in different magnetic properties. The magnetic performance of the specimens is characterized by determining hysteresis loops (B–Hcurves), power losses, and maximum magnetic flux density at frequencies between 50 and 1000 Hz. At constant mass, the different structures induced by using various hatching strategies have a strong influence on the hysteresis losses. These losses can be significantly reduced by applying a targeted structure design. The modified specimens show superior magnetic properties at sub‐kHz compared to some soft magnetic materials fabricated by means of conventional methods and laser powder bed fusion (PBF‐L).
Hollow Hierarchical Cu2O‐Derived Electrocatalysts Steering CO2Reduction to Multi‐Carbon Chemicals at Low Overpotentials
Authors: Li Jinhan , Xu Keqiang , Liu Fangming , Li Youzeng , Hu Yanfang , Chen Xijie , Wang Huan , Xu Wence , Ni Youxuan , Ding Guoyu , Zhao Tete , Yu Meng , Xie Wei , Cheng Fangyi 
Published: April 2023

AbstractThe electrochemical reduction of carbon dioxide into multi‐carbon products (C2+) using renewably generated electricity provides a promising pathway for energy and environmental sustainability. Various oxide‐derived copper (OD‐Cu) catalysts have been showcased, but still require high overpotential to drive C2+production owing to sluggish carbon–carbon bond formation and low CO intermediate (*CO) coverage. Here, the dilemma is circumvented by elaborately devising the OD‐Cu morphology. First, computational studies propose a hollow and hierarchical OD‐Cu microstructure that can generate a core–shell microenvironment to inhibit CO evolution and accelerate *CO dimerization via intermediate confinement and electric field enhancement, thereby boosting C2+generation. Experimentally, the designed nanoarchitectures are synthesized through a heteroseed‐induced approach followed by electrochemical activation. In situ spectroscopic studies further elaborate correlation between *CO dimerization and designed architectures. Remarkably, the hierarchical OD‐Cu manifests morphology‐dependent selectivity of CO2reduction, giving a C2+Faradaic efficiency of 75.6% at a considerably positive potential of −0.55 V versus reversible hydrogen electrode.
Aging Property of Halide Solid Electrolyte at the Cathode Interface
Authors: Kim Wonju , Noh Joohyeon , Lee Sunyoung , Yoon Kyungho , Han Sangwook , Yu Seungju , Ko Kun‐Hee , Kang Kisuk 
Published: May 2023

AbstractHalide solid electrolytes have recently emerged as a promising option for cathode‐compatible catholytes in solid‐state batteries (SSBs), owing to their superior oxidation stability at high voltage and their interfacial stability. However, their day‐ to month‐scale aging at the cathode interface has remained unexplored until now, while its elucidation is indispensable for practical deployment. Herein, the stability of halide solid electrolytes (e.g., Li3InCl6) when used with conventional layered oxide cathodes during extended calendar aging is investigated. It is found that, contrary to their well‐known oxidation stability, halide solid electrolytes can be vulnerable to reductive side reactions with oxide cathodes (e.g., LiNi0.8Co0.1Mn0.1O2) in the long term. More importantly, the calendar aging at a low state of charge or as‐fabricated state causes more significant degradation than at a high state of charge, in contrast to typical lithium‐ion batteries, which are more susceptible to high‐state‐of‐charge calendar aging. This unique characteristic of halide‐based SSBs is related to the reduction propensity of metal ions in halide solid electrolytes and correlated to the formation of an interphase due to the reductive decomposition triggered by the oxide cathode in a lithiated state. This understanding of the long‐term aging properties provides new guidelines for the development of cathode‐compatible halide solid electrolytes.
Research and Application Progress of Conductive Films in Energy Storage Devices
Authors: Zhao Pan , Xiong Lilong , Li Xiang , Guo Yuan , Xie Yuehong , Du Xianfeng 
Published: April 2023

AbstractThe shortage of fossil energy and the environmental pollution caused by its use promote the development of renewable clean new energy. Energy storage devices are the best choice to convert and store them into efficient and convenient electric energy, and the light weight of the conductive film plays an important role in energy storage devices. Conductive films as electronic conduction layers have become a research hotspot due to their high electronic conductivity, environment‐friendly, low cost, flexibility, transmittance, high chemical stability, good film forming, and excellent mechanical properties. The material selection, conductivity, preparation methods, and adhesion to the substrate of the conductive films all affect the performance of the energy storage devices. Herein, the conductive properties of conductive films of metal materials, carbon materials, conductive polymers, metal oxides, metal nitrides, and other compounds are reviewed. The application of conductive films as electron conduction layers in solar cells, supercapacitors, lithium‐ion batteries, and solid aluminum electrolytic capacitors is analyzed. The future development trend of conductive films in energy storage devices is prospected.
TRACE‐Omicron: Policy Counterfactuals to Inform Mitigation of COVID‐19 Spread in the United States
Authors: O'Gara David , Rosenblatt Samuel F. , Hébert‐Dufresne Laurent , Purcell Rob , Kasman Matt , Hammond Ross A. 
Published: April 2023

AbstractThe Omicron wave is the largest wave of COVID‐19 pandemic to date, more than doubling any other in terms of cases and hospitalizations in the United States. In this paper, a large‐scale agent‐based model of policy interventions that could have been implemented to mitigate the Omicron wave is presented. The model takes into account the behaviors of individuals and their interactions with one another within a nationally representative population, as well as the efficacy of various interventions such as social distancing, mask wearing, testing, tracing, and vaccination. We use the model to simulate the impact of different policy scenarios and evaluate their potential effectiveness in controlling the spread of the virus. The results suggest the Omicron wave could have been substantially curtailed via a combination of interventions comparable in effectiveness to extreme and unpopular singular measures such as widespread closure of schools and workplaces, and highlight the importance of early and decisive action.
Particle and Heavy Ion Transport Code System‐Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy
Authors: Shigehira Takafumi , Hanafusa Tadashi , Igawa Kazuyo , Kasai Tomonari , Furuya Shuichi , Nishimori Hisakazu , Maeda Yoshinobu , Michiue Hiroyuki , Fujimura Atsushi 
Published: April 2023

AbstractBoron neutron capture therapy (BNCT) is a radiation therapy that selectively kills cancer cells at the cellular level using the boron neutron capture reaction (BNCR) (10B(n.α)7Li). The amount of boron 10B delivers in boronophenylalanine (BPA)‐BNCT to achieve anti‐tumor effects is ≈15–40 ppm. The same is true for all boron drugs; however, whether the same amount of 10B is required for other boron drugs with different accumulation characteristics has not been intensively investigated. Therefore, herein, a virtual cell model with intracellular organelles is prepared, and the BPA equivalent dose concentration to the cell nucleus is analyzed using particle and heavy ion transport code system‐based microdosimetry. Additionally, the intranuclear minimal region (IMR) is set as a reference for the concept of the intranuclear domain in the microdosimetric kinetic model, and the BPA equivalent dose concentration to the IMR is estimated. The required boron delivery dose greatly varies depending on the dose assessment based on the accumulation characteristics of boron agents in intracellular organelles. Evaluation of the BNCR effect according to the accumulation characteristics without being influenced by the specified value of 15–40 ppm is recommended.
Multicellular Bioprinting of Biomimetic Inks for Tendon‐to‐Bone Regeneration
Authors: Du Lin , Qin Chen , Zhang Hongjian , Han Fei , Xue Jianmin , Wang Yufeng , Wu Jinfu , Xiao Yin , Huan Zhiguang , Wu Chengtie 
Published: April 2023

AbstractTendon‐to‐bone interface has a hierarchical structure and gradient component that are conducive to distributing the stresses to achieve movement. Conventional biomaterials lack the capacity to induce synchronous repair of multiple tissues, resulting in the failure of the interface repair. Biomimetic strategies have attracted enormous attention in the field of complex structure regeneration because they can meet the different physiological requirements of multiple tissues. Herein, a biomimetic ink mimicking tendon/bone tissues is developed by combining tendon/bone‐related cells and Mo‐containing silicate (MS) bioceramics. Subsequently, biomimetic multicellular scaffolds are fabricated to achieve the simulation of the hierarchical structure and cellular composition of tendon‐to‐bone interfaces by the spatial distribution of the biomimetic inks via 3D bioprinting, which is of great significance for inducing the regeneration of complex structures in the interface region. In addition, attributed to the desirable ionic microenvironment created by MS bioceramics, the biomimetic scaffolds possess the dual function of inducing tendon/bone‐related cells tenogenic and osteogenic differentiation in vitro, and promote the integrated regeneration of tendon‐to‐bone interfaces in vivo. The study offers a feasible strategy to construct biomimetic multicellular scaffolds with bifunction for inducing multi‐lineage tissue regeneration, especially for regenerating soft‐to‐hard tissue interfaces.
A community psychology for migrant justice: Critically examining border violence and resistance during the COVID‐19 syndemic
Authors: Esposito Francesca , Rebelo Dora , Olanrewaju Moshood , Vine Megan , Fernandes‐Jesus Maria , Bodden Debi , Kalokoh Aminata , Olson Bradley 
Published: May 2023

AbstractThis article explores the magnifying lenses of the COVID‐19 syndemic to highlight how people racialized as migrants and refugees have been—and continue to be—disproportionally harmed. We use empirical evidence collected in our scholarly/activist work in Europe, Africa, South Asia, and the United States to examine migrant injustice as being produced by a combination of power structures and relations working to maintain colonial global orders and inequalities. This is what has been defined as “border imperialism.” Our data, complemented by evidence from transnational solidarity groups, show that border imperialism has further intersected with the hygienic‐sanitary logics of social control at play during the COVID‐19 period. This intersection has resulted in increasingly coercive methods of restraining people on the move, as well as in increased—and new—forms of degradation of their lives, that is, an overall multiplication of border violences. At the same time, however, COVID‐19 has provided a unique opportunity for grassroot solidarity initiatives and resistance led by people on the move to be amplified and extended. We conclude by emphasizing the need for community psychologists to take a more vigorous stance against oppressive border imperialist regimes and the related forms of violence they re/enact.
Synthesis of Arylamines via a Tandem Petasis Borono‐Mannich/ Nucleophilic Substitution Reaction
Authors: Li Guang‐Lin , Chen Yu , Li Xiang‐Sai , Yang Qi , Gu Ying‐Chun , Yu Ya‐Qin , Xu Da‐Zhen 
Published: May 2023

AbstractAn efficient and practical one‐pot reaction for the synthesis of diarylmethyl anilines from easy available materials of salicylaldehydes, arylboronic acids and aromatic amines has been successfully developed. All the reactions proceed smoothly under transition‐metal‐free conditions via a p‐TSA promoted tandem Petasis borono‐Mannich/ nucleophilic substitution reaction, providing highly functionalized amines with wide functional groups in good to excellent yields. A reasonable explanation for this transformation was suggested.
Cellulose acetate/nanoclay composite membranes with enhanced mechanical properties and improved permeance in gas separation
Authors: Juntadech Nithinart C. , Juntadech Thanate , Niamlang Sumonman , Jongsomjit Bunjerd 
Published: May 2023

AbstractDiethyl ether is a valuable chemical product in petrochemical industry used in different applications. In diethyl ether (DEE) production by the dehydration of ethanol (EtOH), the products from DEE production are commonly mixed with EtOH and the % yield of DEE generally has not exceeded 60%. This contribution describes the preparation and performance of hollow fiber membranes for the separation of gaseous product (DEE) and reactant (EtOH). Cellulose acetate (CA)/nanoclay (NC)‐based hollow fiber composite membranes were prepared using a wet spinning process of CA solution and the addition of hydrophilic NC particles to improve the mechanical properties and permeability. According to the findings, the 20 wt% CA/0.5 wt% NC hollow fiber showed the higher mechanical strength than the 20 wt% CA hollow fiber without NC. Moreover, the 20 wt% CA hollow fiber without NC provided EtOH and DEE permeances of 8.44 × 10−11 and 4.25 × 10−10 mol m−2 s−1 Pa−1, respectively, while the 20 wt% CA/0.5 wt% NC hollow fiber showed higher EtOH and DEE permeances of 6.50 × 10−10 and 8.49 × 10−9 mol m−2 s−1 Pa−1 plausibly because of the higher porosity based on the SEM images. Furthermore, both CA hollow fiber membranes were selective for DEE over EtOH and were more selective with the addition of NC.
Study on the synthesis of soluble copolymer polyarylate from asymmetric bisphenol A derivative (2,2‐bis(4‐hydroxyphenyl)butane/9,9‐bis(4‐hydroxyphenyl)fluorene) monomer
Authors: Wang Zhoufeng , Liu Yingying , Wang Bolin , Long Xiubo , Hu Junwei 
Published: May 2023

AbstractA series of polyarylates composed of different bisphenol monomers were synthesized by interfacial polymerization using 9,9‐bis(4‐hydroxyphenyl)fluorene (BHPF), 2,2‐bis(4‐hydroxyphenyl)butane (BPB), terephthaloyl chloride (TPC), and isophthaloyl chloride (IPC) as raw materials. The DFT calculations showed that the energy required for the reaction of BHPF with TPC/IPC was between 15.82 and 16.04 Kcal/mol, which was higher than the energy required for the reaction of BPB with TPC/IPC of 8.05–8.40 Kcal/mol. The solubility test showed that the solubility of BHPF‐BPB‐type polyarylate was better than that of BPB‐type polyarylate in various organic solvents withTgranging from 199.3 to 215.0°C, indicating that the solubility was improved while increasing theTgof the products. The weight loss (T5%) and maximum weight loss (Tmax) of BHPF‐BPB‐type polyarylates under N2atmosphere ranged from 464.6–489.4°C and 521.7–534.6°C, indicating good thermal stability. The tensile strength of the BHPF‐BPB‐type polyarylates ranged from 53.21 to 61.23 MPa, Young's modulus ranged from 1479.66 to 1867.23 MPa and elongation at break ranged from 19.5% to 30.1%. The mechanical property test showed that the BHPF‐BPB‐type polyarylates have high tensile strength. These characteristics indicate that BHPF‐BPB‐type polyarylates have a very broad potential for application in engineering plastics.
Spectroscopic evidence for adsorption of natural organic matter on microplastics
Authors: Paul Andrea , Reese Michelle , Goldhammer Tobias , Schmalsch Claudia , Weber Jens , Bannick Claus G. 
Published: April 2023

AbstractThe interaction of microcroplastics (MP) with dissolved organic matter, especially humic substances, is of great importance in understanding the behavior of microplastics in aquatic ecosystems. Surface modification by humic substances plays an essential role in transport and interaction of MP with abiotic and biotic components. Previous studies on the interaction between MP and humic substances were largely based on a model compound, humic acid (Sigma‐Aldrich). In our work, we therefore investigated the interaction of natural organic matter (NOM) sampled from a German surface water with low‐density polyethylene particles (LDPE). High‐pressure size exclusion chromatography (HPSEC) and UV/vis absorption and fluorescence spectroscopy were used to characterize the incubation solutions after modifications due to the presence of LDPE, and Raman spectroscopy was used to characterize the incubated microplastics. While the studies of the solutions generally showed only very small effects, Raman spectroscopic studies allowed clear evidence of the binding of humic fractions to MP. The comparison of the incubation of NOM and a lignite fulvic acid which also was tested further showed that specific signatures of the humic substances used could be detected by Raman spectroscopy. This provides an elegant opportunity to conduct broader studies on this issue in the future.