bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Intra‐Base Pair Proton Transfer on Dissociation and Singlet Oxygenation of 9‐Methyl‐8‐Oxoguanine−1‐Methyl‐Cytosine Base‐Pair Radical Cations
Authors: Moe May Myat , Tsai Midas , Liu Jianbo 
Published: September 2023

Abstract8‐Oxoguanosine is the most common oxidatively generated base damage and pairs with complementary cytidine within duplex DNA. The 8‐oxoguanosine−cytidine lesion, if not recognized and removed, not only leads to G‐to‐T transversion mutations but renders the base pair being more vulnerable to the ionizing radiation and singlet oxygen (1O2) damage. Herein, reaction dynamics of a prototype Watson−Crick base pair [9MOG ⋅ 1MC]⋅+, consisting of 9‐methyl‐8‐oxoguanine radical cation (9MOG⋅+) and 1‐methylcystosine (1MC), was examined using mass spectrometry coupled with electrospray ionization. We first detected base‐pair dissociation in collisions with the Xe gas, which provided insight into intra‐base pair proton transfer of 9MOG⋅+ ⋅ 1MC
[9MOG − HN1]⋅ ⋅ [1MC+HN3′]+ and subsequent non‐statistical base‐pair separation. We then measured the reaction of [9MOG ⋅ 1MC]⋅+ with 1O2, revealing the two most probable pathways, C5‐O2 addition and HN7‐abstraction at 9MOG. Reactions were entangled with the two forms of 9MOG radicals and base‐pair structures as well as multi‐configurations between open‐shell radicals and 1O2 (that has a mixed singlet/triplet character). These were disentangled by utilizing approximately spin‐projected density functional theory, coupled‐cluster theory and multi‐referential electronic structure modeling. The work delineated base‐pair structural context effects and determined relative reactivity toward 1O2 as [9MOG − H]⋅>9MOG⋅+>[9MOG − HN1]⋅ ⋅ [1MC+HN3′]+≥9MOG⋅+ ⋅ 1MC.
Green human resource management: A comprehensive investigation using bibliometric analysis
Authors: Shah Priya , Singh Dubey Richa , Rai Shashikant , Renwick Douglas W. S. , Misra Saurabh 
Published: September 2023

AbstractThis study reviews green human resource management (GHRM) via bibliometric analysis of extant literature in the field of business and management. We used bibliometric, R Studio program for descriptive analysis and network analysis, to analyze 595 documents from the Web of Science and Scopus data. The study aims to provide a comprehensive overview of the evolution of GHRM and the structures that define it. This article discusses the emerging keywords and research area along with the growth patterns in the area of GHRM during 2002–2022. The findings suggest that publication on GHRM began over 25 years ago and has continued to grow since then. The number of publications in this field of study has doubled over the last 10 years. Emerging themes include Green human resource practices, corporate social responsibility (CSR), innovation, environmental performance, circular economy, and sustainable development. Potential research areas have been suggested by drawing a complete picture of the conceptual framework. The study will help policy‐makers, corporates and academicians unravel the practical and theoretical aspects of GHRM and identify pertinent issues that require attention.
What do we know about ESG and risk? A systematic and bibliometric review
Authors: De Giuli Maria Elena , Grechi Daniele , Tanda Alessandra 
Published: September 2023

AbstractEnvironmental, Social and Governance (ESG) issues have become particularly relevant in the agendas of policymakers, investment decisions by companies and asset allocation process of investors. However, the transition to a greener and more sustainable economic system is not without risks. The literature has investigated the relationship between ESG and risk in different ways, through multiple perspectives and approaches. We select all documents with “ESG” and “Risk” in the title, abstracts and keywords available in Scopus and, after removing non‐relevant papers, we are left with a sample of 589 documents published in the period 1983–2022. To provide a view of the most important studies, we also focus on the most cited documents to discuss the methodological approaches and main results. The results show that over time, ESG has gained increasing attention from the literature, but researchers work in isolation and there is no single approach or leading core topic driving academic productivity; a clear taxonomy of ESG risks appears to be missing. To the best of our knowledge, this paper is the first to discuss research on ESG and risk from a financial perspective. The results highlight some existing gaps in the literature that can provide a hint for the development of the topic by researchers. These include a clearer taxonomy of ESG risks that can affect investors' and companies' decisions, a greater effort to evaluate how ESG risks distribute and spill from one sector to another and the inclusion of emerging economies and small and medium‐sized enterprises in the samples.
CSR transmission modes in the buyer–supplier relationship: The case studies of garment companies in Vietnam
Authors: Dinh Ha Le Hai , Le Duong Thuy , Le Thi Thai Ha , Nguyen Minh Hoang , Nguyen Hung Vu 
Published: September 2023

AbstractThis paper investigates the mechanisms under which the transmission of CSR practices and values could be successfully attained in buyer‐supplier relationships, particularly in the context of garment supply chains that involve developing country suppliers. Examining the buyer‐supplier dyadic CSR transmission process through the lens of an inter‐organizational learning perspective rather than the traditional compliance‐based one, this study proposes four distinct CSR transmission modes: Monitoring – Compliance, Capacity building – Internalization, Demonstration – Adaptation, and Role modeling – Imitation. Notably, the findings reveal that without buyers' stringent CSR management techniques, CSR practices and values can still be successfully transmitted to suppliers with the aid of proper learning facilitators. The theoretical and practical contributions of the paper are also provided.
Controllability, reachability, observability performance analysis of ultra‐high voltage converter cascaded systems based on switched linear system model
Authors: Yang Ru , Tao Jintong , Ding Zekang , Hu Wei , Liao Hui 
Published: September 2023

SummaryUltra‐high voltage converters are usually employed to transform low voltage to high voltage in microgrids to produce renewable energy. However, it is challenging to develop control techniques due to the complicated structure of ultra‐high voltage converters and the numerous power switches and circuit components, which leads to poor dynamic characteristics of the system and a marked increase in fault rates. In order to understand the control theoretical characteristics of the ultra‐high voltage converter and provide a theoretical basis for circuit parameter analysis and control strategy design, this paper takes the boost converter cascaded system as an example to establish an accurate switching linear system model, discusses the control theoretical characteristics of the ultra‐high voltage converter in detail, and uses the decision theorem to draw the conclusion that the system is structurally controllable, reachable, and observable, simplifying the difficulty of analysis. The simulation and experimental findings show that the conclusion was drawn correctly. The research findings will give the boost converter cascaded systems modulation approach and circuit parameter design a theoretical foundation.
Predictors of neurofeedback treatment outcome in binge‐eating disorder: An exploratory study
Authors: Rösch Sarah A. , Schmidt Ricarda , Hilbert Anja 
Published: September 2023

AbstractObjectiveKnowledge on predictors for treatment response to psychotherapy in binge‐eating disorder (BED) is mixed and not yet available for increasingly popular neurofeedback (NF) treatment targeting self‐regulation of aberrant brain activity. This study examined eating disorder‐ and psychopathology‐related predictors for NF treatment success in BED.MethodPatients with BED (N = 78) were randomized to 12 sessions of real‐time functional near‐infrared spectroscopy (rtfNIRS)‐NF, targeting individual prefrontal cortex signal up‐regulation, electroencephalography (EEG)‐NF, targeting down‐regulation of fronto‐central beta activity, or waitlist (WL). The few studies assessing predictors for clinical outcomes after NF and evidenced predictors for psychotherapy guided the selection of baseline eating disorder‐related predictors, including objective binge‐eating (OBE) frequency, eating disorder psychopathology (EDP), food cravings, and body mass index (BMI), and general psychopathology‐related predictors, including depressive and anxiety symptoms, impulsivity, emotion dysregulation, and self‐efficacy. These questionnaire‐based or objectively assessed (BMI) predictors were regressed on outcomes OBE frequency and EDP as key features of BED at post‐treatment (t1) and 6‐month follow‐up (t2) in preregistered generalized mixed models (https://osf.io/4aktp).ResultsHigher EDP, food cravings, and BMI predicted worse outcomes across all groups at t1 and t2. General psychopathology‐related predictors did not predict outcomes at t1 and t2. Explorative analyses indicated that lower OBE frequency and higher self‐efficacy predicted lower OBE frequency, and lower EDP predicted lower EDP after the waiting period in WL.DiscussionConsistent with findings for psychotherapy, higher eating disorder‐related predictors were associated with higher EDP and OBE frequency. The specificity of psychopathological predictors for NF treatment success warrants further examination.Public SignificanceThis exploratory study firstly assessed eating disorder‐ and psychopathology‐related predictors for neurofeedback treatment outcome in binge‐eating disorder and overweight. Findings showed an association between higher eating disorder symptoms and worse neurofeedback outcomes, indicating special needs to be considered in neurofeedback treatment for patients with a higher binge‐eating disorder symptom burden. In general, outcomes and assignment to neurofeedback treatment may be improved upon consideration of baseline psychological variables.
Voluntary Regulation by the Pharmaceutical Industry—Which Role for the Shadow of Hierarchy and Social Pressure?
Authors: Töller Annette Elisabeth 
Published: September 2023

In 2004, the voluntary FSA Codex was adopted by part of the German pharmaceutical industry and was revised several times in the subsequent 10 years. The codex—as many others in OECD countries do—addresses the delicate relationship between the pharmaceutical industry and physicians. This article presents a case study of the FSA Codex and addresses the question of why this voluntary regulation was adopted and revised. In doing so, the article challenges a strong position in the literature, that voluntary regulation is dependent on the shadow of hierarchy. In addition, it addresses the question how social pressure can trigger voluntary regulation. For this case, rational‐choice institutionalism and normative institutionalism in combination prove useful for identifying the driving forces and causal mechanisms of voluntary regulation.
Flavonoids contribute most to discriminating aged Guang Chenpi (Citrus reticulata ‘Chachi’) by spectrum‐effect relationship analysis between LC‐Q‐Orbitrap/MS fingerprint and ameliorating spleen deficiency activity
Authors: Sun Xiaoming , Deng Haidan , Shan Baojun , Shan Yunqi , Huang Jiaying , Feng Xinshu , Tang Xiaomin , Ge Yuewei , Liao Peiran , Yang Quan 
Published: September 2023

AbstractTo further explore the mechanism of “the longer storage time, the better bioactivity” of aged Guang Chenpi, the dry pericarp of Citrus reticulata ‘Chachi’ (CRC), a series of activity assessments were performed on spleen deficiency mice. The constituents in CRC with different storage years were analyzed by LC‐Q‐Orbitrap/MS. A total of 53 compounds were identified, and CRC stored for more than 5 years showed higher flavonoid content, especially that of polymethoxyflavones. Anti‐spleen deficiency bioactivity analysis among various CRC with different storage years showed aged CRC (stored for more than 3 years) could significantly alleviate fatigue and depression behaviors much better, increase D‐xylose and gastrin secretion, and upregulate the expression of the linking protein occludin in the colon walls. Results from 16S rDNA sequencing showed that aged CRC could downregulate the abundance of Enterococcus, Gemmata, Citrobacter, Escherichia_Shigella, and Klebsiella, which were significantly overrepresented in the model group. Bacteroides, Muribaculum, Alloprevotella, Paraprevotella, Alistipes, Eisenbergiella, and Colidextribacter were downregulated in the model group but enriched in the CRC groups. At last, the spectrum‐effect relationship analysis indicated that flavonoids such as citrusin III, homoeriodictyol, hesperidin, nobiletin, and isosinensetin in aged CRC showed the highest correlation with better activity in ameliorating spleen deficiency by regulating gut microbiota. Flavonoids contribute most to discriminating aged CRC and could disclose the basis of “the longer storage time, the better bioactivity” of aged Guang Chenpi.
Increased prevalences of head and neck cancers in patients with Sjögren's syndrome
Authors: Yang Tzong‐Hann , Cheng Yen‐Fu , Chen Chin‐Shyan , Lin Herng‐Ching 
Published: September 2023

AbstractObjectiveThis study aimed to investigate prevalences of head and neck cancers in patients with and those without Sjögren's syndrome using a population‐based dataset.MethodsWe retrieved sampled patients from Taiwan's Longitudinal Health Insurance Database. This study included 38 930 patients with Sjögren's syndrome and 155 720 propensity‐score matched comparison patients without Sjögren's syndrome.ResultsChi‐squared tests revealed that there was a statistically significant difference in the prevalences of head and neck cancers between patients with Sjögren's syndrome and comparison patients (1.77% vs. 1.22%, p < 0.001). The odds ratio for head and neck cancers for patients with Sjögren's syndrome relative to the comparison group was 1.452 (95% CI = 1.325–1.592).ConclusionsOur study demonstrated that patients with Sjögren's syndrome face increased odds of head and neck cancers, encompassing several sites including the oral cavity, oropharynx, nasopharynx, and thyroid.
Patterns of spread and anatomical prognostic factors of pre‐auricular cutaneous squamous cell carcinoma extending to the temporal bone
Authors: Schachtel Michael J. C. , Gandhi Mitesh , Bowman James J. , Panizza Benedict J. 
Published: September 2023

AbstractBackgroundImprovements can be made in the management and staging of advanced pre‐auricular cutaneous squamous cell carcinoma (cSCC). We aimed to analyze radiological patterns of spread and clinico‐anatomical prognostic factors.MethodsRetrospective review of 54 patients with pre‐auricular cSCC (cutaneous/nodal) who underwent temporal bone resection with curative intent.ResultsInvolvement of the cartilaginous external auditory canal (EAC) (79.6%) and retromandibular space (63.0%) was common. Styloid process/anterior carotid sheath (ACS) (11.1%) and bony EAC (7.4%) involvement were rare. ACS involvement resulted in high rates of involved surgical margins (100%) and poor outcomes on univariable analysis. Negative prognostic factors on multivariable analysis included salvage surgery and invasion of the bony EAC, mandible, pterygoid muscle(s), and dura.ConclusionThe bony EAC and ACS can form temporary barriers to tumor spread, with the latter representing a potential limit of resectability. Prognostic factors revealed can lead to the development of a more appropriate staging tool.
Measurement of polydoctoring as a crucial component of fragmentation of care among patients with multimorbidity: Cross‐sectional study in Japan
Authors: Ando Takayuki , Sasaki Takashi , Abe Yukiko , Nishimoto Yoshinori , Hirata Takumi , Haruta Junji , Arai Yasumichi 
Published: September 2023

AbstractBackgroundCare fragmentation, characterized by the uncoordinated involvement of multiple healthcare providers, leads to inefficient and ineffective healthcare, posing a significant challenge in managing patients with multimorbidity. In this context, “polydoctoring,” where patients see multiple specialists, emerges as a crucial aspect of care fragmentation. This study seeks to develop an indicator to assess polydoctoring, which can subsequently enhance the management of multimorbidity.MethodsBaseline survey data from the Kawasaki Aging and Wellbeing Project (KAWP) involving independent community‐dwelling older adults aged 85–89 were utilized in this cross‐sectional study. Polydoctoring measure was defined as the number of regularly visited facilities (RVFs). The association of RVF with the Fragmentation of Care Index (FCI) and the outcome measures of polypharmacy and ambulatory care costs were examined as indicators of care fragmentation.ResultsThe analysis comprised 968 participants, with an average of 4.70 comorbid chronic conditions; 65.3% of the participants had two or more RVFs, indicating polydoctoring. A significant correlation between RVF and FCI was observed. Modified Poisson regression analyses revealed associations between higher RVF and increased prevalence ratio of polypharmacy. Likewise, a higher RVF was associated with higher outpatient medical costs.ConclusionsRVF was significantly correlated with FCI, polypharmacy, and higher outpatient medical costs. Unlike complex indices, RVF is simple and intuitively comprehensible. Further research is needed to evaluate the impact of care fragmentation on patient outcomes, considering factors such as RVF thresholds, patient multimorbidity, and social support. Understanding the influence of polydoctoring can enhance care quality and efficiency for patients with multimorbidity.
Explore the optimal timing for administering the second dose of the varicella vaccine in China
Authors: Sun Xiang , Wang Yong , Zhang Lei , Liu Yuanbao , Xu Ling‐Xiao , Chen Qiang , Sun Hui , Wang Fangfang , Wang Zhiguo , Wang Wen 
Published: September 2023

AbstractThe prevalence of varicella in China has been increasing annually, with a relatively high incidence rate of breakthrough cases. Administering two doses of the varicella vaccine (Varv) proves to be the most effective measure. The objective of this study is to assess the immunogenicity of two doses of the Varv at varying intervals and explore the optimal timing for administering the second dose of the Varv. Utilizing a prospective cohort study design, the quantification of varicella immunoglobulin G (IgG) antibodies' geometric mean concentrations (GMC) is conducted through glycoprotein‐based enzyme‐linked immunosorbent assay (gpELISA). A total of 903 infants were included in the per‐protocol population. After completing the first dose of the Varv, the GMC of antibody after 1 month (Group A) was 463.8 (447.6−480.1) mIU/mL. There was a statistically significant difference in GMC and seroconversion rates among the groups (B/C/D) that received the second dose of the Varv (p < 0.05). Multiple comparisons revealed that the group with a 3‐year interval between the two vaccine doses had a higher GMC of 665.2 (622.6−707.8) mIU/mL compared to the group with a 1‐year interval of 611.1 (577.1−645.3) mIU/mL and the group with a 5‐year interval of 564.7 (540.1−589.4) mIU/mL. To effectively prevent and control the varicella epidemic in Jiangsu Province, two dose Varv vaccination is recommended, the optimal time point for the second dose Varv is 3 years after the first vaccination.
Architecture of soil microaggregates: Advanced methodologies to explore properties and functions
Authors: Amelung Wulf , Tang Ni , Siebers Nina , Aehnelt Michaela , Eusterhues Karin , Felde Vincent J. M. N. L. , Guggenberger Georg , Kaiser Klaus , Kögel‐Knabner Ingrid , Klumpp Erwin , Knief Claudia , Kruse Jens , Lehndorff Eva , Mikutta Robert , Peth Stephan , Ray Nadja , Prechtel Alexander , Ritschel Thomas , Schweizer Steffen A. , Woche Susanne K. , Wu Bei , Totsche Kai U. 
Published: September 2023

AbstractThe functions of soils are intimately linked to their three‐dimensional pore space and the associated biogeochemical interfaces, mirrored in the complex structure that developed during pedogenesis. Under stress overload, soil disintegrates into smaller compound structures, conventionally named aggregates. Microaggregates (<250 µm) are recognized as the most stable soil structural units. They are built of mineral, organic, and biotic materials, provide habitats for a vast diversity of microorganisms, and are closely involved in the cycling of matter and energy. However, exploring the architecture of soil microaggregates and their linkage to soil functions remains a challenging but demanding scientific endeavor. With the advent of complementary spectromicroscopic and tomographic techniques, we can now assess and visualize the size, composition, and porosity of microaggregates and the spatial arrangement of their interior building units. Their combinations with advanced experimental pedology, multi‐isotope labeling experiments, and computational approaches pave the way to investigate microaggregate turnover and stability, explore their role in element cycling, and unravel the intricate linkage between structure and function. However, spectromicroscopic techniques operate at different scales and resolutions, and have specific requirements for sample preparation and microaggregate isolation; hence, special attention must be paid to both the separation of microaggregates in a reproducible manner and the synopsis of the geography of information that originates from the diverse complementary instrumental techniques. The latter calls for further development of strategies for synlocation and synscaling beyond the present state of correlative analysis. Here, we present examples of recent scientific progress and review both options and challenges of the joint application of cutting‐edge techniques to achieve a sophisticated picture of the properties and functions of soil microaggregates.
Effect of beef long‐storage under different temperatures and vacuum‐packaging conditions on meat quality, oxidation processes and microbial growth
Authors: Luzardo Santiago , Saadoun Ali , Cabrera María C , Terevinto Alejandra , Brugnini Giannina , Rodriguez Jesica , de Souza Guillermo , Rovira Pablo , Rufo Caterina 
Published: September 2023

AbstractBACKGROUNDThe global beef market demands the meat industry to ensure product quality and safety in markets that are often very distant. The present study aimed to evaluate the effects of chilled (CH, 120 d) and chilled‐then‐frozen (CHF, 28 d + 92 d) storage conditions of beef vacuum packaged (VP) and vacuum packaged with antimicrobial (VPAM) on meat quality, oxidative status and microbial loads. Treatments resulted from the combination of storage condition and packaging type: VP + CH, VP + CHF, VPAM + CH and VPAM + CHF.RESULTSWarner–Bratzler shear force values decreased in all treatments after 28 d of chilling. Except for VP + CH, L* values (lightness) of meat color did not differ in each treatment as the storage time increased. Meat from VP + CH had greater a* values than CHF treatments on day 120 of storage. A consumer panel did not detect differences in tenderness, flavor and overall liking between VP and VPAM beef, but they preferred CHF steaks rather than CH beef. TBARS values did not differ between VP and VPAM and between CH and CHF at any time during the storage period. At the end of storage time, all treatments except VP + CHF presented a greater concentration of thiols than at 48 h post‐mortem. On day 120 of storage, VP + CH had greater catalase enzyme activity than CHF treatments while VP + CH and VP + CHF showed a greater superoxide dismutase activity than VPAM + CHF. Storage condition (CH or CHF) had a greater impact on microbial counts than the type of packaging.CONCLUSIONFreezing meat after an ageing period represents a suitable strategy to extend beef storage life without a detrimental impact on its quality. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.