bluuebunny/crossref_metadata_2025_split huggingface dataset:
The matrilineal society of Meghalaya: trends of family planning and its implications on maternal health
Authors: Shullai Wansalan Karu , Singh A. Santa , Agarwal Manika 
Published: June 2023

Background: The key health indicators pertaining to maternal health are TFR, contraceptive usage and MMR. As per the NFHS V, the use of any contraceptive method is 27.4% and total fertility rate is 2.9 in Meghalaya, which reflects on the poor performance of the state towards achieving the goals set by the National Health Policy 2017. The current MMR of Meghalaya is 211/1 lakh live birth, one of the highest amongst the Indian states. The two most important causes of maternal mortality in Meghalaya are post-partum haemorrhage and anaemia- both avoidable causes of maternal mortality related to higher order pregnancies and lack of adequate spacing between two consecutive pregnancies, thereby increasing the importance of contraceptive use. The aim of the study was to identify factors associated with poor uptake of contraceptive measures and their implications on maternal health in a matrilineal society.
Methods: A cross sectional study was conducted in the department of obstetrics and gynaecology, NEIGRIHMS where 200 patients, indigenous to Meghalaya, were recruited over a period of one year and were interviewed using a validated questionnaire pertaining to family planning practices.
Results: Factors such as number of live births, religion and residence were seen to influence the utilization of contraceptive methods.
Conclusions: There is still a wide gap to be filled- more sincere and dedicated efforts are needed to empower women to make informed decisions by increasing awareness about the importance of family planning and its implications on maternal health.
Port site tuberculosis: is an epidemic on shore?
Authors: Ovi Mir Rasekh Alam , Hossain As Saba , Nasrin Shamima , Salahuddin Gazi Muhammad , Mustafa A. S. M. Feroz , Sagar SM Iftekhar Uddin , Hasan Tanvir 
Published: June 2023

Background: Bangladesh has to carry an extensive burden of tuberculosis in varied form of presentation. In the era of minimally invasive surgery (MIS) port site tuberculosis is usually a rare incidence. Among all the infections it has been identified as a prolong burden for both patients and surgeons. This study was done to notify such rare complication of MIS and tried to find out is there really an upsurge of this infection in Bangladesh.
Methods: This retrospective study was done an urban area of Bangladesh during September 2020 to June 2021. 483 laparoscopic surgeries were done by six different surgeons in 5 different hospitals during September 2020 to January 2021. All surgeons have minimum five years experiences in laparoscopic surgery. 20 minutes emersion of the laparoscopic instruments into activated glutaraldehyde solution 2% (CIDEX) was used as method of chemical sterilization. Other surgical instruments were sterilized by conventional autoclave method.
Results: Among them 87 patients developed port infections. 66 (75.86%) patients of this 87 developed non-healing ulcer. Biopsy from the ulcer showed granulomatous tissue in 56 patients and the other 10 was nonspecific inflammation. CAT I anti-TB chemotherapy was initiated to all the patients and all improved by this therapy. Use of 3.54% glutaraldehyde instead of 2% or immersion of instruments for a longer period (more than 20 minutes) could be tried in larger scale to prove its efficacy.
Conclusions: National tuberculosis control program (NTP) should give more emphasis on cutaneous tuberculosis as the morbidity of this disease is high. Surgeons of Bangladesh should admit and report such incidences as, if it is documented in other areas of the country, it may need to develop a national guideline to prevent and treat port site tuberculosis.
Pozycja prawna i zadania Kościelnego Inspektora Ochrony Danych w świetle unijnych i polskich regulacji
Authors: Ciechanowska Justyna 
Published: June 2023

RODO jest aktem prawnym Unii Europejskiej, który wyznacza nowe standardy ochrony danych osobowych związane z ich przetwarzaniem. Przyjęte w nim rozwiązania są celowe i stanowią solidny fundament ochrony danych osobowych obywateli państw członkowskich Unii Europejskiej. Biorąc pod uwagę niezależność i autonomię Kościoła katolickiego przewidzianą m.in. w Konstytucji RP oraz Konkordacie między Stolicą Apostolską a Rzecząpospolitą Polską z dnia 28 lipca 1993 r., autor ma na celu przedstawienie statusu, sposobu wybierania, uprawnień i kompetencji Kościelnego Inspektora Ochrony Danych. Celem niniejszej analizy jest również odpowiedź, czy KIOD jako organ nadzoru w zakresie ochrony danych osobowych wykonuje zadania w sposób niezależny, tj. bez jakiegokolwiek wpływu z zewnątrz w toczące się postępowania.
Dyskryminacja ze względu na religię w zatrudnieniu z perspektywy relacji Państwo-Kościół – wybrane zagadnienia
Authors: Driczinski Sławomir 
Published: June 2023

Opracowanie dotyczy wybranych aspektów funkcjonowania zasady niedyskryminacji ze względu na religię w zatrudnieniu. W tekście zostały poruszone tematy związane z samym pojęciem dyskryminacji ze względu na religię. Zasygnalizowano znaczenie orzecznictwa sądów międzynarodowych w polskim wewnętrznym porządku prawnym. Scharakteryzowano podstawowe regulacje prawne odnoszące się do podjętego tematu z częściowym uwzględnieniem dosyć ubogiego orzecznictwa. Dokonano też odniesienia do regulacji australijskiej zagadnienia dyskryminacji ze względu na religię, w kontekście potrzeby uporządkowania i poszerzenia przedmiotowej regulacji w polskim (a być może także europejskim) porządku prawnym.
ВПЛИВ ІНДУСТРІЇ 4.0 НА РІВЕНЬ КОНКУРЕНТОСПРОМОЖНОСТІ КРАЇН СВІТУ
Authors: Косич М. В. , Александрова О. Ю. 
Published: June 2023

Для України нагальною необхідністю є посилення процесів пошуку чинників підвищення національної конкурентоспроможності. Сьогодні у світі ми спостерігаємо процеси переходу до четвертої промислової революції, яка пропонує не тільки поєднання інформаційно-комунікаційних технологій з промисловим виробництвом, а використання кіберфізичних систем, штучного інтелекту, 3D-друк і т.д.Найбільшою перепоною у впровадженні досягнень Індустрії 4.0 в Україні є недостатнє фінансування наукових досліджень та розробок, скорочення кількості дослідницьких організацій та самих дослідників. В Україні на розвиток Індустрії 4.0 має вплив державна політика у галузі інновацій й науково-технологічного розвитку, поточний рівень розвитку освіти, науки та технологій.
IMPLEMENTATION OF TECHNOLOGY FOR IMPROVING THE QUALITY OF SEGMENTATION OF MEDICAL IMAGES BY SOFTWARE ADJUSTMENT OF CONVOLUTIONAL NEURAL NETWORK HYPERPARAMETERS
Authors: Prochukhan Dmytro 
Published: June 2023

Background. The scientists have built effective convolutional neural networks in their research, but the issue of optimal setting of the hyperparameters of these neural networks remains insufficiently researched. Hyperparameters affect model selection. They have the greatest impact on the number and size of hidden layers. Effective selection of hyperparameters improves the speed and quality of the learning algorithm. It is also necessary to pay attention to the fact that the hyperparameters of the convolutional neural network are interconnected. That is why it is very difficult to manually select the effective values of hyperparameters, which will ensure the maximum efficiency of the convolutional neural network. It is necessary to automate the process of selecting hyperparameters, to implement a software mechanism for setting hyperparameters of a convolutional neural network. The author has successfully implemented the specified task.
Objective. The purpose of the paper is to develop a technology for selecting hyperparameters of a convolutional neural network to improve the quality of segmentation of medical images..
Methods. Selection of a convolutional neural network model that will enable effective segmentation of medical images, modification of the Keras Tuner library by developing an additional function, use of convolutional neural network optimization methods and hyperparameters, compilation of the constructed model and its settings, selection of the model with the best hyperparameters.
Results. A comparative analysis of U-Net and FCN-32 convolutional neural networks was carried out. U-Net was selected as the tuning network due to its higher quality and accuracy of image segmentation. Modified the Keras Tuner library by developing an additional function for tuning hyperparameters. To optimize hyperparameters, the use of the Hyperband method is justified. The optimal number of epochs was selected - 20. In the process of setting hyperparameters, the best model with an accuracy index of 0.9665 was selected. The hyperparameter start_neurons is set to 80, the hyperparameter net_depth is 5, the activation function is Mish, the hyperparameter dropout is set to False, and the hyperparameter bn_after_act is set to True.
Conclusions. The convolutional neural network U-Net, which is configured with the specified parameters, has a significant potential in solving the problems of segmentation of medical images. The prospect of further research is the use of a modified network for the diagnosis of symptoms of the coronavirus disease COVID-19, pneumonia, cancer and other complex medical diseases.
Quaternion Quantum Mechanics II: Unraveling the Mysteries of Gravity and Dirac Equation within the Planck-Kleinert Crystal
Authors: Danielewski Marek , Sapa Lucjan , Roth Chantal 
Published: June 2023

The correspondence between classical and quaternion quantum equations, permits considering the universe (vacuum) as an ideal elastic solid. Elementary particles would have to be standing or soliton-like waves. Tension induced by the compression and twisting of the elastic medium would increase the energy density, consequently generate a gravity forcing and affect the wave speed. Consequently the gravity could be described by an index of refraction.
Theory was created by combining the Cauchy model of the elastic continuum with the Planck-Kleinert crystal hypothesis. The quaternion-imaginary Lagrange’an, the quaternion motion equation and the quaternionic oscillator allowed deriving:
- The Schrödinger equation from the functional integral, which identifies the quaternion-imaginary quantum Hamiltonian.
- The 2nd order wave equation system describing both the bosons and the gravity in terms of quaternionic Poisson equation.
- The first order quaternionic wave equation system.
- The family of the second order wave equation systems describing both the particles and the generated quaternionic force-fields (four-potentials).
- The fundamental Planck and gravity constants.
-	The quaternionic continuity equation in an ideal elastic solid.
Efficient degradation of phenanthrene by biocharsupported nano zero-valent iron activated persulfate: Performance evaluation and mechanism insights
Authors: ZHOU Lai , Wang Yichen , LI Danqiong , Zhang Jiehui , Zhu Xueqiang 
Published: June 2023

Abstract

Biochar-supported nano zero-valent iron (BC@ nZVI) is a novel and efficient non-homogeneous activation material. This study aimed to identify the primary pathways, the degradation performance and mechanism of phenanthrene (PHE) with persulfate activated by BC@ nZVI (BC@ nZVI/PS). BC@ nZVI as an activation material for PS was prepared by liquid phase reduction method. BC@ nZVI was characterized using scanning electron microscopy, transmission electron microscopy, and X-ray diffractometer. The effects of the Fe-to-carbon mass ratio and BC@ nZVI dosage were investigated, and a pseudo-first-order kinetic model was used to evaluate the PHE degradation. The results showed that BC supported nano zero-valent iron and inhibited the agglomeration of nZVI, which improved the activation efficiency for PS. The most suitable ratio of Fe to C (Fe/C = 1:4) and the optimum dosages of BC@ nZVI (0.6 g/L) were determined. It was determined by radical quenching and electron paramagnetic resonance (EPR) that the oxidative radicals in the BC@ nZVI/PS system were mainly SO4-· and ·OH, where the dominant free radical under acidic and neutral conditions is SO4-·, and under alkaline conditions is ·OH. This study can provide mechanism insights of PHE degradation in water with BC@ nZVI activation of the Na2S2O8 system.
Effect of integrated use of nutrients on foliar nutrient content, fruit nutrient uptake, soil properties, yield and economics of Papaya (Carica papaya L.) cv. Coorg Honey Dew
Authors: Sethy Bijaya , Ranjan Ranjan. Kumar Tarai. , Subrat Subrat Kumar Behera , Narayan Narayan Panda , Mishra Prabhanjan Mishra , Sanjay Sanjay Kumar Pradhah 
Published: June 2023

Abstract

An experiment was conducted during the year 2015–2016 and 2016–2017 at the experimental plot, College of Agriculture, Chiplima, Odisha University of Agriculture and Technology, Sambalpur, Odisha to find out the effect of integrated use nutrients (organic, inorganic and biofertilizers ) on foliar nutrient content, fruit nutrient uptake, soil properties and economics of papaya cv. Coorg Honey Dew. The cumulative fruit yield was found highest (55.89 kg/plant) in T7which was closely followed by (53.91 kg/plant) under treatment T8. The nutrient content in leaf ranges from 1.07–2.13% (N), 0.14–0.27% (P) and 1.98–2.98% (K) after final harvest of the fruits. The uptake of nutrients by papaya fruits per hectare was observed to be 340 kg nitrogen, 104 kg phosphorus and 451 kg potassium in 100% RDF + PSB + AZS + AZO and minimum (18,9 and 49 kg) obtained in control. The NPK content in soil was maximum in100% RDF + PSB + AZS + AZO (158 kg, P 28 kg and K 133 kg per ha) and minimum was recorded in control (124,11 and 113 kg). Similarly higher organic carbon (0.58g/kg soil) was obtained in 100% RDF + PSB + AZS + AZO with lower (0.39 g/kg) in control. The soil microbial population was found to be maximum in 100% RDF + PSB + AZS + AZO. Highest B: C ratio (3.30) was noticed in 75% RDF + PSB + AZS + AZO followed by 100% RDF + PSB + AZO (3.25) and 100% RDF + PSB + AZS (3.24).
Intermediate filaments promote glioblastoma cell invasion by controlling cell deformability and mechanosensitive gene expression
Authors: Etienne-Manneville Sandrine 
Published: June 2023

Abstract
Cancer invasion turns a locally growing tumour into a live-threatening disease. Unravelling the molecular signature of invasive cells and their mechanisms of invasion is essential to identify therapeutic targets. While the cytoskeleton is known to support cell mechanical properties required for invasion, the role of intermediate filaments (IFs) is often overlooked. Here we investigated the role of IFs in glioblastoma (GBM), the most common and aggressive primary brain tumour, which is characterized by its high invasive capacity, allowing it to evade classical treatments. Following in silico analysis of published single cell RNA sequencing data of GBM samples which shows that high expression of IF genes correlates with pro-migration markers, we generated IF-depleted GBM cells to demonstrate that the cytoplasmic IF network promotes GBM cell invasion in vitro and in vivo. Mechanical measurement and biochemical analyses show that IFs influence cell invasion by increasing cell stiffness, limiting nuclear deformations, and controlling mechanosensitive gene expression and matrix degradation. Our results reveal the crucial role of IFs in tumour cell mechanics and invasion and suggest that the IF expression pattern can serve as a molecular marker of cells driving glioblastoma invasion.
Does silicon inEugenia myrcianthes Nied. seedlings under water stress contribute in the tolerance and recovery?
Authors: Foresti Andressa Carolina , Scalon Silvana de Paula Quintão , Santos Cleberton Correia , Reis Lucas Coutinho , Linné Jéssica Aline 
Published: June 2023

Abstract

Purpose: Silicon (Si) could contribute to the stability of photosystem II processes and gas exchange. Moreover, it can increase antioxidant enzyme activity, maintaining the growth of E. myrcianthes under water fluctuation, favoring seedling tolerance and recovery after stress suspension. This study aimed to evaluate the silicon effect on E. myrcianthes subjected to water fluctuation and the potential recovery of photosynthetic and enzymatic metabolism and seedling growth after stress suspension.
Methods: Two water regimes: continuous irrigation (I), with 75% of the water retention capacity of the substrate, and water stress (E), with irrigation suspension followed by flooding. The water regimes were associated with different Si concentrations: 0, 2, and 4 mmol L-1. The seedlings were evaluated in five periods: Time zero (T0), with initial evaluations and irrigation suspension; First photosynthesis close to zero under water deficit - 1st P0; First recovery - 1st REC; Second photosynthesis close to zero under flooding - 2nd P0; Second recovery - 2nd REC.
Results: Water fluctuation negatively affected the photosynthetic and enzymatic metabolism of E. myrcianthes. However, we observed 100% survival of all seedlings, suggesting the physiological plasticity of the species. Applying 2 mmol L-¹ of silicon to the seedlings helped them tolerate the stressful effect of water fluctuation.
Conclusion: Water stress decreased the development of E. myrcianthes seedlings, damaging the photochemical and biochemical metabolism of photosynthesis, increasing antioxidant enzyme activity, and reducing root growth and seedling quality. However, Si application at concentrations of 2 mmol L-¹ mitigated water stress effects, favoring seedling development and tolerance to water fluctuation. The species can adjust to stressful conditions and shows potential for survival and tolerance at this developmental stage, recovering its metabolism and growth after stress.
A study of a narrative approach in environmental planning of Amirabad neighborhood in Tehran,Iran
Authors: Allahyari Hadis , Zebardast Lobat 
Published: June 2023

Abstract
One way to study the human mind, including collective memory, is to determine the effects of the environment on humans. One of the ways to identify these effects on humans to some degree is to study the mental narratives of the inhabitants of a place. Therefore, the aim of this study was to analyze the experiences of the residents over time in relation to their role in changing the environment of the neighborhood. Therefore, this research was conducted using the method of cognitive narratology and oral interviews were used in this context. Fourteen residents of the Amirabad neighborhood were selected who had lived in the neighborhood for at least 20 years and were at least 45 years old. The purpose of the narrative and a significant instrument related to the environmental qualities associated with the collective memory of the residents were determined to explain the narratives of the residents by analyzing the items extracted from them. The analysis of the results shows that residents' narratives provide planners with indicators that planners should ultimately evaluate together with the people themselves. This study shows that in Amirabad neighborhood, the factor of needs has been ignored and regardless of this factor, the memorable elements of people are forgotten due to land use changes due to population growth and the increase of special land uses.
Associations of urinary caffeine and caffeine metabolites with metabolic syndrome in U.S. adults
Authors: Qin Linyuan , Zhou Jianli 
Published: June 2023

Abstract
The relationship between caffeine and metabolic syndrome (MetS) has only been evaluated from the perspective of caffeine intake, however, the association between urinary caffeine and MetS is still unclear. This study examines the associations between urinary caffeine and its metabolites and MetS and its components among adults. Data from the US National Health and Nutrition Examination Survey (NHANES) 2011–2014 was analyzed. NHANES is a stratified, multi-stage survey of all non-institutionalized persons in the United States. A total of 2394 subjects without missing data and aged ≥18 years were selected in this study. Urinary caffeine and 14 of its metabolite levels are quantified by the use of high-performance liquid chromatography-electrospray ionization-tandem quadrupole mass spectrometry (HPLC-ESI-MS/MS) with stable isotope-labeled internal standards. We performed principal components analysis (PCA) to investigate the underlying correlation structure of these fifteen features of urinary caffeine and its metabolites and used these principal components (PCs) as independent variables to conduct logistic regression analysis with or without restricted cubic splines (RCS) terms to explore the associations between caffeine metabolites and MetS. Two main PCs that derived from PCA explained 90.67% of the total variance of caffeine and its metabolites. The first PC (PC1, strongly correlated with 1-MU, 1,3-DMU, 1,7-DMU, 1,3,7-TMU, 1-MX, 1,3-DMX, 1,7-DMX, 1,3,7-TMX and AAMU) was positively correlated with risk of MetS (OR=1.27, P<0.001) and all its components (all ORs>1, all P-values<0.001) in the unadjusted models, while in the adjusted models, it was positively correlated with MetS (OR=1.16, P=0.042) and central obesity (OR=1.22, P<0.001). In the unadjusted model, there were significant associations between the second PC (PC2, correlated with 3-MU, 7-MU, 3,7-DMU, 3-MX, 7-MX and 3,7-DMX) and MetS (OR=1.11, P=0.030) and central obesity (OR=1.16, P<0.001), while in the adjusted models, PC2 was positively associated with MetS (OR=1.15, P=0.035) and central obesity (OR=1.15, P=0.005), and negatively associated with raised triglycerides (TG) (OR=0.84, P=0.008). Moreover, we observed U-shaped associations between PC1 and the risk of raised TG both in unadjusted (Pnon-linear = 0.017) and adjusted (Pnon-linear = 0.014) models. Urinary caffeine metabolites were positively associated with the risk of MetS and its components through a variety of linear or non-linear patterns. Excessive consumption of coffee increases the risk of developing MetS and its related diseases.
ZmHMA3 enhances heavy mental Zn stress tolerance and mediates Zn transport in Maize
Authors: Lv Gui-Hua , Li You-Qiang , Chen Jian-Jian , Wu Zhen-Xing , Wu Wen-Mei , Wu Xiao-Hong , Lin Hai-Jian , Wang Tingzhen 
Published: June 2023

Abstract
Maize ((Zea mays L.) is one of the three major grains in the world, widely cultivated globally. Heavy metal Zn pollution poses great risks to corn growth and food security, posing a serious threat to the environment and human health. HMA belongs to the transport protein of the heavy metal ATPase family and can transport Zn2+ and Cd2+ across membranes. To identify the gene function of maize ZmHMA3 in response to Zn pollution, this study constructed a CRISPR-Cas9 mediated ZmHMA3 knockout mutant, using maize inbred line B104 as the genetic background. Under heavy metal Zn stress, gene specific expression, subcellular localization, agronomic traits, root morphology indicators, antioxidant indicators, and Zn content in various parts and subcellular components of cells were measured. Zmhma3 reduced various growth indicators (plant height, fresh weight, dry weight, and water content) and root morphology indicators of maize, decreased antioxidant enzyme activity, increased membrane permeability, and increased zinc accumulation. Various parameters indicate that under Zn stress, Zmhma3 exhibits weaker tolerance than WT, demonstrating the positive regulatory role of the ZmHMA3 gene in Zn stress. These have laid the foundation for exploring the regulatory mechanisms of plants in response to Zn pollution in the future. Key worlds Maize; HMA; heavy metal pollution; Zn; CRISPR-Caas9; gene function