bluuebunny/crossref_metadata_2025_split huggingface dataset:
Highly conservative Allen–Cahn-type multi-phase-field model and evaluation of its accuracy
Authors: Aihara Shintaro , Takada Naoki , Takaki Tomohiro 
Published: May 2023

Abstract
In the engineering field, it is necessary to construct a numerical model that can reproduce multiphase flows containing three or more phases with high accuracy. In our previous study, by extending the conservative Allen–Cahn (CAC) model, which is computationally considerably more efficient than the conventional Cahn–Hilliard (CH) model, to the multiphase flow problem with three or more phases, we developed the conservative Allen–Cahn type multi-phase-field (CAC–MPF) model. In this study, we newly construct the improved CAC–MPF model by modifying the Lagrange multiplier term of the previous CAC–MPF model to a conservative form. The accuracy of the improved CAC–MPF model is evaluated through a comparison of five models: three CAC–MPF models and two CH–MPF models. The results indicate that the improved CAC–MPF model can accurately and efficiently perform simulations of multiphase flows with three or more phases while maintaining the same level of volume conservation as the CH model. We expect that the improved CAC–MPF model will be applied to various engineering problems with multiphase flows with high accuracy.

Graphic abstract
Submixing and shift-invariant stochastic games
Authors: Gimbert Hugo , Kelmendi Edon 
Published: May 2023

AbstractWe study optimal strategies in two-player stochastic games that are played on a finite graph, equipped with a general payoff function. The existence of optimal strategies that do not make use of memory and randomisation is a desirable property that vastly simplifies the algorithmic analysis of such games. Our main theorem gives a sufficient condition for the maximizer to possess such a simple optimal strategy. The condition is imposed on the payoff function, saying the payoff does not depend on any finite prefix (shift-invariant) and combining two trajectories does not give higher payoff than the payoff of the parts (submixing). The core technical property that enables the proof of the main theorem is that of the existence of$$\epsilon$$ϵ-subgame-perfect strategies when the payoff function is shift-invariant. Furthermore, the same techniques can be used to prove a finite-memory transfer-type theorem: namely that for shift-invariant and submixing payoff functions, the existence of optimal finite-memory strategies in one-player games for the minimizer implies the existence of the same in two-player games. We show that numerous classical payoff functions are submixing and shift-invariant.
Tiagabine and zonisamide differentially regulate the glial properties in an astrocyte-microglia co-culture model of inflammation
Authors: Ismail Fatme Seval , Faustmann Pedro M. , Förster Eckart , Corvace Franco , Faustmann Timo Jendrik 
Published: May 2023

AbstractDue to the role of astrocytes and microglia in the pathophysiology of epilepsy and limited studies of antiseizure medication (ASM) effects on glial cells, we studied tiagabine (TGB) and zonisamide (ZNS) in an astrocyte-microglia co-culture model of inflammation. Different concentrations of ZNS (10, 20, 40, 100 µg/ml) or TGB (1, 10, 20, 50 µg/ml) were added to primary rat astrocytes co-cultures with 5–10% (M5, physiological conditions) or 30–40% (M30, pathological inflammatory conditions) microglia for 24 h, aiming to study glial viability, microglial activation, connexin 43 (Cx43) expression and gap-junctional coupling. ZNS led to the reduction of glial viability by only 100 µg/ml under physiological conditions. By contrast, TGB revealed toxic effects with a significant, concentration-dependent reduction of glial viability under physiological and pathological conditions. After the incubation of M30 co-cultures with 20 µg/ml TGB, the microglial activation was significantly decreased and resting microglia slightly increased, suggesting possible anti-inflammatory features of TGB under inflammatory conditions. Otherwise, ZNS caused no significant changes of microglial phenotypes. The gap-junctional coupling was significantly decreased after the incubation of M5 co-cultures with 20 and 50 µg/ml TGB, which can be related to its anti-epileptic activity under noninflammatory conditions. A significant decrease of Cx43 expression and cell–cell coupling was found after the incubation of M30 co-cultures with 10 µg/ml ZNS, suggesting additional anti-seizure effects of ZNS with the disruption of glial gap-junctional communication under inflammatory conditions. TGB and ZNS differentially regulated the glial properties. Developing novel ASMs targeting glial cells may have future potential as an “add-on” therapy to classical ASMs targeting neurons.
Estimation of measurement uncertainty for the quantification of protein by ID-LC–MS/MS
Authors: Beasley-Green Ashley , Heckert N. Alan 
Published: May 2023

AbstractThe emergence of mass spectrometry (MS)-based methods to quantify proteins for clinical applications has led to the need for accurate and consistent measurements. To meet the clinical needs of MS-based protein results, it is important that the results are traceable to higher-order standards and methods and have defined uncertainty values. Therefore, we outline a comprehensive approach for the estimation of measurement uncertainty of a MS-based procedure for the quantification of a protein biomarker. Using a bottom-up approach, which is the model outlined in the “Guide to the Expression of Uncertainty of Measurement” (GUM), we evaluated the uncertainty components of a MS-based measurement procedure for a protein biomarker in a complex matrix. The cause-and-effect diagram of the procedure is used to identify each uncertainty component, and statistical equations are derived to determine the overall combined uncertainty. Evaluation of the uncertainty components not only enables the calculation of the measurement uncertainty but can also be used to determine if the procedure needs improvement. To demonstrate the use of the bottom-up approach, the overall combined uncertainty is estimated for the National Institute of Standards and Technology (NIST) candidate reference measurement procedure for albumin in human urine. The results of the uncertainty approach are applied to the determination of uncertainty for the certified value for albumin in candidate NIST Standard Reference Material® (SRM) 3666. This study provides a framework for measurement uncertainty estimation of a MS-based protein procedure by identifying the uncertainty components of the procedure to derive the overall combined uncertainty.
Graphical Abstract
Applying and Assessing Participatory Approaches in an Environmental Flows Case Study
Authors: Mussehl Meghan , Webb J. Angus , Horne Avril , Rumpff Libby , Poff LeRoy 
Published: May 2023

AbstractEnvironmental flows (e-flows) management takes place within a complex social-ecological system, necessitating the involvement of diverse stakeholders and an appreciation of a range of perspectives and knowledge types. It is widely accepted that incorporating participatory methods into environmental flows decision-making will allow stakeholders to become meaningfully involved, improving potential solutions, and fostering social legitimacy. However, due to substantial structural barriers, implementing participatory approaches can be difficult for water managers. This paper assesses the effectiveness of an e-flows methodology that combines elements of structured decision-making and participatory modeling, whilst constrained by project resources. Three process-based objectives were identified by the group at the start of the process: improving transparency, knowledge exchange, and community ownership. We evaluated the success of the approach according to those objectives using semi-structured interviews and thematic analysis. In evaluating how well the participatory approach achieved the process objectives, we found that at least 80% of respondents expressed positive sentiment in every category (n = 15). We demonstrate that the values-based process objectives defined by the participant group are an effective tool for evaluating participatory success. This paper highlights that participatory approaches can be effective even in resource-constrained environments when the process is adapted to fit the decision-making context.
Management and Outcome of Blunt Pancreatic Trauma: A Retrospective Cohort Study
Authors: Lu Xiaozhi , Gao Hao , Jiang Kuirong , Miao Yi , Wei Jishu 
Published: May 2023

AbstractBackgroundPancreatic injury is rare, but it has a high mortality rate and its optimal treatment remains controversial. This study aimed to evaluate the clinical characteristics, management strategies, and outcomes of patients with blunt pancreatic injury.MethodsThis retrospective cohort study was performed on patients with a confirmed blunt pancreatic injury who were admitted to our hospital from March 2008 to December 2020. The clinical characteristics and outcomes of patients receiving different management strategies were compared. The risk factors for in‐hospital mortality were evaluated by performing a multivariate regression analysis.ResultsA total of 98 patients diagnosed with blunt pancreatic injury were identified, with 40 patients having undergone nonoperative treatment (NOT) and 58 patients having undergone surgical treatment (ST). The overall in‐hospital deaths were 6 (6.1%), including 2 (5.0%) and 4 (6.9%) in the NOT and ST groups, respectively. Pancreatic pseudocysts occurred in 15 (37.5%) and 3 (5.2%) of the NOT and ST groups, respectively, showing a significant difference between the two groups (P < 0.001). In the multivariate regression analysis, concomitant duodenal injury (OR = 14.42, 95% CI 1.27–163.52; P = 0.031) and sepsis (OR = 43.47, 95% CI, 4.15–455.75; P = 0.002) were independently associated with in‐hospital mortality.ConclusionsExcept for the higher incidence of pancreatic pseudocysts in the NOT group than in the ST group, there were no significant differences in the other clinical outcomes between the two groups. Concomitant duodenal injury and sepsis were the risk factors for in‐hospital mortality.
Gelatinous versus non-gelatinous zooplankton: their value as food for planktivorous coral reef fishes
Authors: Gahan James , Bellwood David R. , Bellwood Orpha , Schlaefer Jodie 
Published: May 2023

AbstractCoral reefs are highly productive ecosystems, in part due to the productivity of planktivorous fishes. The planktivorous fish community contains two distinct groups which target either the gelatinous or the non-gelatinous fractions of the incoming zooplankton. However, the nutritional value of these prey fractions and, consequently, their potential contribution to planktivorous fish productivity are poorly understood. We explored the zooplankton fractions potential contribution to planktivorous fish productivity (our function of interest), by quantifying the nutritional content a key trait of the gelatinous and non-gelatinous prey fractions which are accessible to reef-associated diurnal planktivores. By combining vertical plankton tows with stoichiometric analyses, we found that the three zooplankton community fractions—gelatinous, > 2 mm non-gelatinous and < 2 mm non-gelatinous—were all relatively good sources of nitrogen, with median C:N values of 4.81:1, 4.22:1 and 4.62:1, respectively. The delivery of gN m−2 to our study reef over a flood tide was then estimated. The abundant < 2 mm non-gelatinous community delivered the largest gN m−2 (median: 0.88 gN m−2 6 h−1), which was estimated to be one to two orders of magnitude greater than the delivery from the > 2 mm non-gelatinous (0.06 gN) and gelatinous (0.03 gN) communities, respectively. Overall, our results highlight the quality of both gelatinous and non-gelatinous zooplankton as prey for planktivorous fishes, emphasizing the potential importance of the often-overlooked gelatinous fraction.
Preparation of para-aramid aerogel fiber structurally colored by light scattering through wet spinning and supercritical drying
Authors: Ajikawa Katsumi , Tabata Isao , Hirogaki Kazumasa 
Published: May 2023

AbstractThis research is an investigation of the preparation conditions for para-aramid aerogel fibers that are structurally colored by Rayleigh scattering, an angle-independent structural color. It is well known that structural color has the angle dependence of colors. However, there is currently a desire for materials with angle-independent structural color. During the fibers’ spinning process, the microstructures of the fibers are generated. The effect of spinning conditions is investigated by measuring the optical properties of the wet gel fibers. The neutralization speed of negatively charged PPTA fibrils has a significant impact on the formation of the dense microstructure. Spinning under the fast neutralization speed condition makes it possible to achieve the blue-colored fiber derived from Rayleigh scattering. The influence of neutralization speed on the microstructure of the fibers is confirmed by FE-SEM characterization. Furthermore, spinning using a narrow inner diameter needle decreases the whiteness component derived from Mie scattering of the fibers, resulting in a more vivid blue color. The angle-independent structurally colored fibers hold great promise for application in clothing, interiors, and industrial materials.
Improving children’s ability to remember intentions: a literature review on strategies to improve prospective memory during childhood
Authors: Cottini Milvia 
Published: May 2023

AbstractChildren often fail to remember executing intentions because prospective memory (PM) does not completely develop until late adolescence or young adulthood. PM failures are often observed in children and can have negative consequences on their everyday lives. Thus, in the last 50 years, various strategies to support children’s PM have been designed and evaluated, such as prompting children to use different encoding modalities, such as verbal, visual, and enacted modalities, or encoding strategies, such as implementation intentions, episodic future thinking (EFT), and performance predictions, as well as providing children with verbal and visual reminders. However, not all these interventions have shown to efficiently enhance PM performance during childhood. The present literature review is aimed at summarizing these interventions and critically examining their effectiveness from a developmental perspective and by considering underlying mechanisms. The type of PM task (event-, time-, and activity-based), cognitive resource demands, and processing overlaps are also considered. Finally, directions for future research and possible applications in everyday life will be discussed.
Reliability and agreement of the timed up and go test in children and teenagers with autism spectrum disorder
Authors: Martín-Díaz Paloma , Carratalá-Tejada María , Molina-Rueda Francisco , Cuesta-Gómez Alicia 
Published: May 2023

AbstractASD patients include a variety of motor deficits; however, these issues have received less scientific attention than other ASD symptoms. Due to understanding and behavioral difficulties, it might be difficult to administer motor assessment measures to children and adolescents with ASD. To evaluate motor challenges in this population, including gait and dynamic balance issues, the timed up and go test (TUG) may be a simple, easy to apply, quick, and inexpensive tool. This test measures in seconds the time it takes for an individual to get up from a standard chair walk 3 m, turn around, walk back to the chair, and sit down again. The study purpose was to evaluate the inter- and intra-rater reliability of TUG test in children and teenagers with ASD. A total of 50 children and teenagers with ASD (43 boys and 7 girls) between 6 and 18 years were included. Reliability was verified by the intraclass correlation coefficient, standard error of measurement, and minimum detectable change. The agreement was analyzed by the Bland–Altman method. A good intra-rater reliability (ICC = 0.88; 95% CI = 0.79–0.93) and an excellent inter-rater reliability (ICC = 0,99; 95% CI = 0.98 to 0.99) were observed. Additionally, Bland–Altman plots demonstrated that there was no evidence of bias in either the replicates or between examiners. Furthermore, the limits of agreement (LOAs) between the testers and test replicates were close, indicating that there was little variation between measurements. Conclusions: The test TUG showed strong intra- and inter-rater reliability values, low proportion of measurement errors, and lack of significant bias based on by test repetition in children and teenagers with ASD. These results could be clinically useful for assessing balance and the risk of falls in children and teenagers with ASD. However, the present study is not free of limitations, such as the use of a non-probabilistic sampling.

What is Known:• People with ASD have a variety of motor deficits that have a prevalence rate almost as common as intellectual disability. In our knowledge, there are no studies that provide data on the reliability of the use of scales or assessment tests in children and adolescents with ASD to measure motor difficulties, such as gait and dynamic balance, in children and teenagers with ASD.• Timed up and go test (TUG) could be a possible tool to measure this motor skills.

What is New:• The reliability and agreement of the Timed up and go test in 50 children and teenagers with autism spectrum disorder showed strong intra- and inter-rater reliability values, low proportion of measurement errors, and lack of significant bias based on by test repetition.
Chemical emasculation in cowpea (Vigna unguiculata (L.) Walp.) and dicotyledonous model species using trifluoromethanesulfonamide (TFMSA)
Authors: Sekiguchi Yuka , Ubi Benjamin Ewa , Ishii Takayoshi 
Published: May 2023

AbstractHybridization plays an indispensable role in creating the diversity associated with plant evolution and genetic improvement of crops. Production of hybrids requires control of pollination and avoidance of self-pollination for species that are predominantly autogamous. Hand emasculation, male sterility genes or male gametocides have been used in several plant species to induce pollen sterility. However, in cowpea (Vigna unguiculata (L.) Walp), a self-pollinated cleistogamous dryland crop, only hand emasculation is used, but it is tedious and time-consuming. In this study, male sterility was effectively induced in cowpea and two dicotyledonous model species (Arabidopsis thaliana (L.) Heynh. and Nicotiana benthamiana Domin) using trifluoromethanesulfonamide (TFMSA). Pollen viability assays using Alexander staining showed that 30 ml of 1000 mg/l TFMSA with two-time treatments of one-week interval at the early stage of the reproductive phase under field or greenhouse conditions induced 99% pollen sterility in cowpea. TFMSA treatment induced non-functional pollen in diploid A. thaliana at two-time treatment of 10 ml of 125–250 mg/l per plant and N. benthamiana at two-time treatment of 10 ml of 250–1000 mg/l per plant. TFMSA-treated cowpea plants produced hybrid seeds when used as the female parent in crosses with non-treated plants used as male parents, suggesting that TFMSA had no effect on female functionality in cowpea. The ease of TFMSA treatment and its effectiveness to induce pollen sterility in a wide range of cowpea genotypes, and in the two model plant species tested in this study, may expand the scope of techniques for rapid pollination control in self-pollinated species, with potential applications in plant breeding and plant reproduction science.
A graph-based approach for minimising the knowledge requirement of explainable recommender systems
Authors: Caro-Martínez Marta , Jiménez-Díaz Guillermo , Recio-Garcia Juan A. 
Published: May 2023

AbstractTraditionally, recommender systems use collaborative filtering or content-based approaches based on ratings and item descriptions. However, this information is unavailable in many domains and applications, and recommender systems can only tackle the problem using information about interactions or implicit knowledge. Within this scenario, this work proposes a novel approach based on link prediction techniques over graph structures that exclusively considers interactions between users and items to provide recommendations. We present and evaluate two alternative recommendation methods: one item-based and one user-based that apply the edge weight, common neighbours, Jaccard neighbours, Adar/Adamic, and Preferential Attachment link prediction techniques. This approach has two significant advantages, which are the novelty of our proposal. First, it is suitable for minimal knowledge scenarios where explicit data such as ratings or preferences are not available. However, as our evaluation demonstrates, this approach outperforms state-of-the-art techniques using a similar level of interaction knowledge. Second, our approach has another relevant feature regarding one of the most significant concerns in current artificial intelligence research: the recommendation methods presented in this paper are easily interpretable for the users, improving their trust in the recommendations.
Recommendation of secure group communication schemes using multi-objective optimization
Authors: Prantl Thomas , Bauer André , Iffländer Lukas , Krupitzer Christian , Kounev Samuel 
Published: May 2023

AbstractThe proliferation of IoT devices has made them an attractive target for hackers to launch attacks on systems, as was the case with Netflix or Spotify in 2016. As the number of installed IoT devices is expected to increase worldwide, so does the potential threat and the importance of securing these devices and their communications. One approach to mitigate potential threats is the usage of the so-called Secure Group Communications (SGC) schemes to secure the communication of the devices. However, it is difficult to determine the most appropriate SGC scheme for a given use case because many different approaches are proposed in the literature. To facilitate the selection of an SGC scheme, this work examines 34 schemes in terms of their computational and communication costs and their security characteristics, leading to 24 performance and security features. Based on this information, we modeled the selection process for centralized, distributed, and decentralized schemes as a multi-objective problem and used decision trees to prioritize objectives.
Identity profiles, motivations for attending university and study-related burnout: differences between Finnish students in professional and non-professional fields
Authors: Mannerström Rasmus , Haarala-Muhonen Anne , Parpala Anna , Hailikari Telle , Salmela-Aro Katariina 
Published: May 2023

AbstractResearch suggests that the reported increase in student mental health issues such as study burnout might be related to students’ identity problems and their motivations for undertaking higher education. The present study added to this line of research by investigating the associations between identity profiles, motives for attending university and study burnout in a sample of Finnish first-year university students (N = 430). Field of study (professional vs non-professional) as a factor was also evaluated because differing occupational prospects might influence one’s sense of identity. The results showed that (1) three identity profiles emerged (i.e. achievement, moderate moratorium and diffusion), (2) students in the achievement profile scored lowest on burnout, (3) the achievement profile was the most common among students studying for entry to a profession and (4) students in the achievement profile scored highest on internal motives for attending university. It is concluded that most students lack a clear sense of identity and that identity measures may be more appropriate in predicting study progression and well-being than motives for attending university or engaging in a field of study.