bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular detection of novel herpesviruses and adenoviruses in two species of Australian freshwater turtles
Authors: Okoh God’spower Richard , Ariel Ellen , Wirth Wytamma , Whitmore David , Horwood Paul F. 
Published: July 2023

AbstractCutaneous lesions were observed in a wild population of freshwater turtles during routine disease surveillance at Alligator Creek, Townsville, Australia. Previous attempts to identify the causative agent of these lesions were unsuccessful; however, existing evidence suggests viral etiology. To further investigate these events, blood samples and lesion, oral and cloacal swabs collected from 128 freshwater turtles at two locations (Alligator Creek and Ross River) were screened for herpesvirus, adenovirus, poxvirus and papillomavirus by polymerase chain reaction. We detected three novel herpesviruses (chelid herpesvirus 1–3) as well as three adenoviruses (saw-shelled turtle adenovirus 1–3). Phylogenetic analyses showed that the herpesviruses formed a distinct clade with the tumour-associated chelonid alphaherpesvirus 5 (Scutavirus chelonidalpha5) within the subfamily Alphaherpesvirinae. The adenoviruses clustered with members of the genus Testadenovirus. Although the novel herpesviruses and adenoviruses could not be linked to the occurrence of cutaneous lesions, further characterisation will help provide better insights into their clinical, epidemiological and conservation significance.
The Influence of Processing Temperature on the Tensile Properties of Melt-Spun PLA Fibres and their Self-Reinforced Composites
Authors: Goutianos Stergios , Beauson Justine 
Published: July 2023

AbstractThe temperature during the consolidation of self-reinforced PLA composites has a significant effect on their mechanical properties. In the present work, the effect of the consolidation or processing temperature on the properties of melt-spun, highly oriented PLA fibres is experimentally studied through single fibre tests. It is shown that the Young’s modulus and strain to failure of PLA fibres increases with exposure to consolidation / processing temperature, and the strength decreases more drastically. Using these data and findings from earlier studies, it is demonstrated that the dependence of the tensile properties of self-reinforced PLA composites on the processing temperature can be directly predicted from the single PLA fiber properties as a function of the processing temperature. This prediction holds true provided that the tensile properties of both the PLA fibers and self-reinforced PLA composites are measured using the same cross-head speed or strain rate.
The Between-Day Reliability of Correlation Properties of Heart Rate Variability During Running
Authors: Van Hooren Bas , Bongers Bart C. , Rogers Bruce , Gronwald Thomas 
Published: July 2023

AbstractThe short-term scaling exponent of detrended fluctuation analysis (DFA-a1) of heart rate variability may be a helpful tool to assess autonomic balance as a prelude to daily, individualized training. For this concept to be useful, between-session reliability should be acceptable. The aim of this study was to explore the reliability of DFA-a1 during a low-intensity exercise session in both a non-fatigued and a fatigued condition in healthy males and females. Ten participants completed two sessions with each containing an exhaustive treadmill ramp protocol. Before and after the fatiguing ramp, a standardized submaximal low-intensity exercise bout was performed during which DFA-a1, heart rate, and oxygen consumption (VO2) were measured. We compared between-session reliability of all metrics prior to the ramps (i.e., non-fatigued status) and after the first ramp (i.e., fatigued status). Intraclass correlation coefficients (ICC) with 95% confidence intervals (CI), the standard error of measurement, and the smallest worthwhile change (SWC) were determined. The ICC and SWC pre fatiguing ramp were 0.85 (95% CI 0.39–0.96) and 5.5% for DFA-a1, 0.85 (0.38–0.96) and 2.2% for heart rate, and 0.84 (0.31–0.96) and 3.1% for VO2. Post fatiguing ramp, the ICC and SWC were 0.55 (0.00–0.89) and 7.9% for DFA-a1, 0.91 (0.62–0.98) and 1.6% for heart rate, and 0.80 (0.17–0.95) and 3.0% for VO2. DFA-a1 shows generally acceptable to good between-session reliability with a SWC of 0.06 and 0.07 (5.5–7.9%) during non-fatigued and fatigued conditions. This suggests that this metric may be useful to inform on training readiness.
Efficacy of combined inactivated vaccines against Vibrio alginolyticus and Streptococcus agalactiae infections in Nile tilapia in Egypt
Authors: Abotaleb Mahmoud M. , Soliman Heba M. , Tawfik Rasha G. , Mourad Ahlam , Khalil Riad H. , Abdel-Latif Hany M.R. 
Published: July 2023

AbstractVibrio alginolyticus and Streptococcus agalactiae are important bacterial pathogens that yielded high losses in Nile tilapia in Egypt. The present study aimed to check the protective efficacy of inactivated whole-cell bivalent vaccines against these pathogens using incomplete Freund’s adjuvant and Montanide™ IMS 1312 VG as adjuvants. The antibody titers have been determined at different weeks post-vaccination (WPV). Moreover, the protection levels against the challenged bacterial pathogens have also been examined in relation to the time-dependent protection at different WPV. The results revealed that serum antibodies were generated in all immunized fish at 1st WPV, peaked at 4th WPV, continued, and gradually decreased from 6th WPV to 14th WPV in all vaccinated groups. In addition, vaccines induced significantly higher protection of the immunized tilapia, manifested by higher survival rates. We noticed that the antibody levels and survival rates of the vaccinated fish by a vaccine adjuvanted by Montanide™ IMS 1312 VG were higher than those produced by a vaccine adjuvanted by incomplete Freund’s adjuvant at different time points. Moreover, no external clinical signs, visceral adhesions, or internal lesions were recorded in the vaccinated tilapia, demonstrating the safety of the formulated vaccines. According to the aforementioned findings, we could suggest that the prepared bivalent vaccines, using the two adjuvant types, are safe and highly protective and could be utilized as promising candidate vaccines to increase the resistance of Nile tilapia against V. alginolyticus and S. agalactiae infections. Moreover, Montanide™ IMS 1312 VG enhanced the immuno-protectivity and exhibited optimum immune response and earlier protection compared to the vaccine adjuvanted by incomplete Freund’s adjuvant, demonstrating its added value during the preparation of tilapia vaccines.
QUARE: towards a question-answering model for requirements elicitation
Authors: Calle Gallego Johnathan Mauricio , Zapata Jaramillo Carlos Mario 
Published: July 2023

AbstractRequirements elicitation is a stakeholder-centered approach; therefore, natural language remains an effective way of documenting and validating requirements. As the scope of the software domain grows, software analysts process a higher number of requirements documents, generating delays and errors while characterizing the software domain. Natural language processing is key in such a process, allowing software analysts for speeding up the requirements elicitation process and mitigating the impact of the ambiguity and misinterpretations coming from natural-language-based requirements documents. However, natural-language-processing-based proposals for requirements elicitation are mainly focused on specific domains and still fail for understanding several requirements writing styles. In this paper, we present QUARE, a question-answering model for requirements elicitation. The QUARE model comprises a meta-ontology for requirements elicitation, easing the generation of requirements-elicitation-related questions and the initial structuration of any software domain. In addition, the QUARE model includes a named entity recognition and relation extraction system focused on requirements elicitation, allowing software analysts for processing several requirements writing styles. Although software analysts address a software domain at a time, they use the same kind of questions for identifying and characterizing requirements abstractions such as actors, concepts, and actions from a software domain. Such a process may be framed into the QUARE model workflow. We validate our proposal by using an experimental process including real-world requirements documents coming from several software domains and requirements writing styles. The QUARE model is a novel proposal aimed at supporting software analysts in the requirements elicitation process.
Traditional prescribed burning of coastal heathland provides niches for xerophilous and sun-loving beetles
Authors: Kerdoncuff Morgane , Måren Inger Elisabeth , Eycott Amy Elizabeth 
Published: July 2023

AbstractIn Western Norway, farmers have traditionally used fire as a management tool in coastal heathlands to enhance the fodder quality for livestock. Rotational prescribed burning increases landscape heterogeneity by creating a mosaic of different regeneration stages of heather. Ground beetle (Coleoptera: Carabidae) responses to fire in traditionally managed coastal heathland have already been studied, but less is known about other beetle groups in this system. We compared the beetle activity between patches of mature and recently burnt heath, by looking at diversity indices, species composition and ecological preferences and traits. Contrary to previous studies, we did not find an increase in beta diversity after disturbance, but we found that prescribed burning offers micro-environmental conditions which enhanced the activity of sun-loving and xerophilous species. We also identified new indicator species for both mature and pioneer heath in five beetle families: Carabidae, Staphylinidae, Curculionidae, Leiodidae, and Scirtidae. Rotational prescribed burning was confirmed to be an efficient conservation tool for specialists without affecting the overall diversity of the site. We recommend the use of several taxa, ecological preferences and traits to assess the impact of prescribed burning and to monitor the condition of traditionally managed coastal heathlands.
COVID-associated complications after reconstructive breast surgery: a retrospective cohort study
Authors: Bubberman J. M. , Claessen J. , Feijen M. M. W. , Meesters-Caberg M. A. J. , Van Kuijk S. M. J. , Van der Hulst R. R. W. J. , Tuinder S. M. H. 
Published: July 2023

Abstract
Purpose
The COVID pandemic significantly influenced reconstructive breast surgery regimens. Many surgeries were cancelled or postponed. COVID entails not only respiratory, but also coagulative symptoms. It, therefore, potentially increases the risk of postoperative complications. The incidence of perioperative COVID infection and its influence on postoperative recovery after reconstructive breast surgery is still unknown.

Methods
This dual center retrospective cohort study included patients that underwent reconstructive breast surgery between March 2020 and July 2021. Post-mastectomy autologous or implant-based breast reconstruction (ABR; IBR), as well as post-lumpectomy oncoplastic partial breast reconstruction (PBR) were eligible. Patient data were extracted from electronic medical records. Data regarding COVID-19 infection was collected through a questionnaire. The primary outcome was complication rate.

Results
The ABR, IBR and PBR groups consisted of 113 (12 COVID-positive), 41 (2 COVID-positive) and 113 (10 COVID-positive) patients. In the ABR and PBR groups, postoperative complications occurred significantly more often in patients with perioperative COVID-infection. Especially impaired wound healing occurred significantly more often in the ABR and PBR breasts, but also at the donor site of ABR patients with perioperative COVID.

Conclusion
Perioperative COVID-infection increases susceptibility to complicated wound healing after reconstructive breast surgery. A possible explanation lies in the dysregulation of haemostasis by the virus, and its direct effects on microvasculature. A hypercoagulable state results. We recommend to postpone elective breast surgery for 4–6 weeks after COVID-19 infection. Also, precautionary measures remain important to minimize the risk of perioperative COVID-19 infection.
Resveratrol as sensitizer in colorectal cancer plasticity
Authors: Brockmueller Aranka , Sajeev Anjana , Koklesova Lenka , Samuel Samson Mathews , Kubatka Peter , Büsselberg Dietrich , Kunnumakkara Ajaikumar B. , Shakibaei Mehdi 
Published: July 2023

Abstract
Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to significant side effects and chemoresistance that can be linked to several resistance-activating biological processes, including an increase in inflammation, cellular plasticity, multidrug resistance (MDR), inhibition of the sentinel gene p53, and apoptosis. As a consequence, tumor cells can escape the effectiveness of chemotherapeutic agents. This underscores the need for cross-target therapeutic approaches that are not only pharmacologically safe but also modulate multiple potent signaling pathways and sensitize cancer cells to overcome resistance to standard drugs. In recent years, scientists have been searching for natural compounds that can be used as chemosensitizers in addition to conventional medications for the synergistic treatment of CRC. Resveratrol, a natural polyphenolic phytoalexin found in various fruits and vegetables such as peanuts, berries, and red grapes, is one of the most effective natural chemopreventive agents. Abundant in vitro and in vivo studies have shown that resveratrol, in interaction with standard drugs, is an effective chemosensitizer for CRC cells to chemotherapeutic agents and thus prevents drug resistance by modulating multiple pathways, including transcription factors, epithelial-to-mesenchymal transition-plasticity, proliferation, metastasis, angiogenesis, cell cycle, and apoptosis. The ability of resveratrol to modify multiple subcellular pathways that may suppress cancer cell plasticity and reversal of chemoresistance are critical parameters for understanding its anti-cancer effects. In this review, we focus on the chemosensitizing properties of resveratrol in CRC and, thus, its potential importance as an additive to ongoing treatments.

Graphical abstract
Wetting of native and acetylated cellulose by water and organic liquids from atomistic simulations
Authors: Sridhar Arun Srikanth , Berglund Lars A. , Wohlert Jakob 
Published: July 2023

AbstractWetting of cellulose by different liquids is interesting from the point of view of the processing of cellulose-based nanomaterials. Here, the contact angles formed by water and several organic liquids on both native and acetylated cellulose were calculated from molecular dynamics simulations. It was found that liquid surface tension was crucial for their wetting behavior. Acetylation decreases the work of adhesion to most liquids investigated, even non-polar ones, while others are not affected. Water has the highest affinity to cellulose, both native and acetylated. The results have implications for liquid infiltration of nanocellulose networks and the interaction of cellulose with different liquids in general.
Highly hydrophobic cellulose acetate mats modified with poly(ethylene oxide-b-propylene oxide-b-ethylene oxide) triblock copolymer and TiO2 nanoparticles by electrospinning
Authors: Gomez-Hermoso-de-Mendoza Joseba , Gutierrez Junkal , Tercjak Agnieszka 
Published: July 2023

AbstractCellulose acetate (CA) mats modified with poly(ethylene oxide-b-propylene oxide-b-ethylene oxide) (PEO-b-PPO-b-PEO or EPE) and sol–gel synthesised titanium oxide (TiO2) nanoparticles were successfully fabricated by using electrospinning technique. Under the same preparation conditions, higher spinnability was achieved for EPE triblock copolymers modified mats. All fabricated mats showed a micrometric multilayer structure, which enabled layer-by-layer peeling. The addition of TiO2 nanoparticles facilitated the peeling process. The diameter of the fibres was ~ 3 times lower after the incorporation of sol–gel synthesised TiO2 nanoparticles. TEM images confirmed that under electrospinning conditions the PPO block domains were able to microphase separated from the PEO block/CA phase. Additionally, the introduction of sol–gel synthesised TiO2 nanoparticles led to an inorganic network formation with nanoparticle size equal to ~ 8 nm in diameter. Moreover, the addition of TiO2 nanoparticles increased the hydrophobicity of the mats and their self-cleaning ability, being more effective for TiO2/CA than for TiO2-EPE/CA due to the partial absorption of water by EPE triblock copolymer. Young’s modulus of fabricated mats improved drastically with the addition of TiO2 nanoparticles, as well as their physical integrity in polar and nonpolar solvents. Fabricated mats with enhanced spinnability, which maintain CA mat features as well as the properties associated with sol–gel synthesised TiO2 nanoparticles, can find a wide range of applications.
Fostering pre-service teachers’ technology acceptance – does the type of engagement with tool-related information matter?
Authors: Özbek Tugce , Wekerle Christina , Kollar Ingo 
Published: July 2023

AbstractPre-service teachers’ often suboptimal use of technology in teaching can be explained by low levels of technology acceptance. The present study aims to investigate how technology acceptance can be promoted. Based on the Technology Acceptance Model by Davis (1986), we hypothesized that encouraging pre-service teachers to constructively engage with rather than passively reading tool-related information should increase their assessments of the tool’s perceived usefulness, perceived ease of use, intention to use and actual use in lesson plans. In an experimental study, N = 53 pre-service teachers were either asked to read a blog post about the potential of a mind mapping tool (passive condition) or to work on small tasks covering the same information as the blog post (constructive condition). Finally, all participants were instructed to develop lesson plans. Contrary to our hypothesis, analyses of variance showed that passive engagement had stronger positive effects on technology acceptance than constructive engagement, i.e., reading a blog post significantly increased pre-service teachers’ perceived ease of use (partial η2 = .15) compared to working constructively on open-ended tasks (p < .01). Exploratory analyses indicated that deeper engagement with the tasks in the constructive condition was associated with lower technology acceptance (r = [–.37; –.27], p < .05). Nevertheless, both conditions yielded a significant increase in intention to use over time, indicating that engagement with information about a tool in general can foster pre-service teachers’ technology acceptance.
Stated Product Choices of Heterogeneous Agents are Largely Consistent with Standard Models
Authors: Dees Bart , Nijman Theo , van Soest Arthur 
Published: July 2023

AbstractIn this paper we analyze how stated choices for the amount of risk in pension assets of Dutch participants in DC pension products vary with their characteristics. We find strong evidence that this variation is in line with standard portfolio choice models. Heterogeneity in age, risk aversion, loss aversion, non-pension financial wealth, the relative importance of DC pension wealth and educational attainment leads to differences in product choice that are largely in line with standard theory. This applies to investment choices in the accumulation phase as well as in the retirement phase.
Full-Scale Fire Resistance Testing and Two-Scale Simulations of Sandwich Panels with Connections
Authors: Xu Qingfeng , Hofmeyer Hèrm , Maljaars Johan , van Herpen Ruud A. P. 
Published: July 2023

AbstractTo understand sandwich panel behaviour under fire, expensive full-scale tests, or potentially more efficient fire-structure simulations can be carried out. However, these simulations have only been demonstrated to work for specific applications, either on the global scale (a fire on a simple panel) or on the small scale (a temperature load on a single screw connection), often loaded by a standard fire curve. In this paper, the quality of simulations for combined situations is investigated, i.e. a furnace fire on a set of panels including details and connections. First two existing tests are introduced, a sandwich panel façade test and a studs bolt test, followed by the presentation of their basic fire-structure simulations. In general, the heat transfer analyses agree well with the tests, whereas the structural response analyses need investigation: For the first test, out-of-plane deflections are overestimated at the beginning of the test. A parameter study indicates that this is most likely due to adhesive decomposition, resulting in face delamination and related instabilities. For the second test, the basic simulation does not show any failure, whereas the test failed by vertical bearing. However, with a two-scale model the ultimate load is estimated, and increasing vertical displacements and the onset of vertical bearing are predicted. It is concluded that future tests should include more simulation-relevant measurements. Also, global-scale models need to include features specific to the structure to be simulated, only known after tests and basic simulations, and connections may be decisive for global-scale behaviour, which can be incorporated by a two-scale model. Finally, the tests exhibited complex behaviour across different scales, and modifications and improvements of the simulations increased their fidelity. Therefore fire-structure simulations should always be verified with tests and compared with basic simulations, and modifications in the simulation models should be anticipated.
Knowledge power or diplomacy? University alliances and the Belt and Road Initiative
Authors: Chou Meng-Hsuan , Demiryol Tolga 
Published: July 2023

AbstractThe growing importance of China as a major actor in international order has generated tremendous interest among social scientists, but scholarly debates remain in their disciplinary confines. Our study connects existing international relations research on China and the Belt and Road Initiative with two concepts in higher education studies—knowledge powerandknowledge diplomacy—to reveal the multi-faceted approach that China applies towards its “outward-oriented” internationalization activities in the knowledge domain. By studying two instances of university alliance-building through the Belt and Road Initiative, an empirically less examined area in both international relations and higher education studies, we demonstrate how China embraces aknowledge diplomacyapproach in the case of the University Alliance of the Silk Road andknowledge powerin the case of the Asian Universities Alliance. We argue that the co-existence of the two approaches points to the aim of China’s multi-faceted approach to its external relations in the knowledge domain. By combining alternative organizational structures and logics embodied in different university alliances, this approach presents a non-hegemonic attempt to normalize China’s network centrality in an interdependent world. We conclude that China’s Belt and Road Initiative university alliance-building efforts should open up a rich analytical space that encourages further exploration through a world-centeredtianxiaheuristic.