bluuebunny/crossref_metadata_2025_split huggingface dataset:
In Situ synthesis of regular channel structure PSC-TiO2 with a remarkably photocatalytic degradation tetracycline efficiency
Authors: LI TAO , Deng Zhihua , Yang Longyan , Huang Jianxiu , Wang Rongfeng , Wang Dawei , Li Huijuan 
Published: September 2023

Abstract
Incorporating carbon doping and regular channel structure peanut shell carbon-TiO2 (PSC-TiO2) is a challenge because the carbon is usually amorphous phase and TiO2 is agglomerated. Here, we propose an in situ synthetic strategy for the regular channel structure PSC-TiO2 by TiCl4 hydrolysis method, and the obtained PSC-TiO2 composites was used for tetracycline (TC) removal. The morphology and structure of as-prepared PSC-TiO2 composites were characterized by X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), Fourier Transform Infrared (FT-IR) and UV-Vis diffuse reflectance spectra (UV-Vis) techniques. All results confirm the regular channel PSC-TiO2 synthesized successfully. As a result of unique channel structure the resulting PSC-TiO2 exhibits remarkably sunlight adsorption-photocatalytic efficiency for the degradation of TC. For 150 mg/L TC solution, the removal efficiency of TC in the PSC-TiO2 (87.0%) was higher than that in the PSC adsorption (39.4%) and pure TiO2 (70.7%) within 60 min. The obtained 15%PSC-TiO2 composite (400 °C, 2h) showed higher light absorption efficiency, C-O-Ti band and regular channel morphological structure, which resulted in the synergistic effect of PSC adsorption and TiO2 photocatalysis performance, and the current study provides a new insight for regular channel PSC-TiO2 preparation and application.
Circulating Calprotectin as a Potential Biomarker of Persistent Olfactory Dysfunctions in Post-COVID-19 Patients
Authors: Francavilla Beatrice , Velletrani Gianluca , Fiorelli Denise , Maurantonio Sara , Passali Francesco Maria , Bernardini Sergio , Girolamo Stefano Di , Nuccetelli Marzia 
Published: September 2023

Abstract

Objective and Design:
This longitudinal prospective study aims to investigate the potential of circulating calprotectin (cCLP) as a biomarker in persistent olfactory dysfunctions following COVID-19 infection.
Materials and Methods
Thirty-six patients with persistent hyposmia or anosmia post COVID-19 were enrolled (HT0) and re-evaluated after three months of olfactory training (HT1). Two control groups included 18 subjects without olfactory defects post COVID-19 (CG1) and 18 healthy individuals (CG2). Nasal and blood samples were collected to assess circulating calprotectin levels.
Results
Higher calprotectin levels were observed in serum and nasal supernatant of hyposmic patients (HT0) compared to control groups (CG1 and CG2). Post-olfactory training (HT1), olfactory function improved significantly, paralleled by decreased calprotectin levels in serum and nasal samples.
Conclusions
Circulating calprotectin holds potential as a biomarker in persistent olfactory dysfunctions after COVID-19. The decrease in calprotectin levels post-olfactory training implies a role in monitoring and evaluating treatment responses. These findings contribute to the growing literature on potential biomarkers in post-COVID-19 olfactory dysfunctions and underscore the importance of investigating novel biomarkers for personalized patient management. Nevertheless, further studies are needed to validate the application of calprotectin assay in nasal diseases and its correlation with nasal cytology.
Association of inflammatory cytokines expression in cerebrospinal fluid with the severity and prognosis of spontaneous intracerebral hemorrhage
Authors: Gu Tianyan , Pan Jingyu , Chen Ling , Li Kai , Wang Li , Zou Zhihao , Shi Qinghai 
Published: September 2023

Abstract
Objective
To investigate the potential diagnostic and prognostic implications of inflammatory cytokine levels in the cerebrospinal fluid (CSF) of Spontaneous intracerebral hemorrhage (SICH) patients upon their initial hospital admission.
Methods
Our cohort comprised 100 patients diagnosed with acute SICH, who presented to the Department of Neurosurgery. Additionally, 50 individuals, devoid of central nervous system (CNS) pathology and treated concomitantly at our facility, were enlisted as controls. CSF specimens, acquired upon hospital entry, underwent quantitative assessment of 10 inflammatory cytokines employing the Mesoscale Discovery Platform (MSD, Rockville, MD, USA) electrochemiluminescence technology, with subsequent validation via enzyme-linked immunosorbent assay (ELISA).
Results
Distinct elevation of IL-6, IL-8, IL-10, and TNF-α levels was evident in the CSF of the SICH subgroup relative to controls. Elevated Glasgow Coma Scale (GCS) scores among SICH patients were concomitantly linked with diminished CSF concentrations of IL-6, IL-8, IL-10, and TNF-α, indicating an inverse relationship. Notably, CSF inflammatory cytokine concentrations were consistently elevated in SICH patients manifesting with hydrocephalus compared to those without. Elevations in IL-6, IL-8, IL-10, and TNF-α in the CSF were significantly pronounced in the poor prognosis cohort (Glasgow Outcome Scale, GOS 1–3) relative to their counterparts with a favorable prognosis (GOS 4–5). The AUC values for the aforementioned cytokines in predicting SICH prognosis were 0.750, 0.728, 0.717, and 0.743, respectively.
Conclusions
The initial CSF levels of IL-6, IL-8, IL-10, and TNF-α upon admission offer significant insights into the severity of neural damage and serve as robust indicators for prognostication in SICH patients.
Study on water injection intensity classification of irregular horizontal-vertical well groups
Authors: Hu Yin , hongjun Qu 
Published: September 2023

Abstract
Horizontal wells with artificial fractures have been proven to be an effective method to develop tight reservoirs. However, inappropriate water injection might lead to non-uniform waterflooding in the group of horizontal producers and vertical injectors. Therefore, the objective of the current study is to optimize the flowrate of vertical injectors in the combination of horizontal and vertical wells. First, a series of numerical models with different relative positions of horizontal and vertical well were built in a tight reservoir. Through numerical simulation and three-dimension (3D) visualization technique, the controlling area of the horizontal well was divided into three areas where injectors follow different flowrates to increase the sweep area and avoid water breakthrough. Then, a numerical model with one horizontal well and three vertical wells was established to study the flowrate ratio between the injectors from different controlling areas. Simulation results show that three injectors with 6:3:1 of flowrate ratio can obtain an extra 2997.6 m3 cumulative oil production than that with 1:1:1 of flowrate ratio.
3-n-Butylphthalide suppresses neuroinflammation through BDNF signaling in postoperative cognitive dysfunction in mice
Authors: miao xiaofei , Zhou Zangong , feng wei , yu ning 
Published: September 2023

Abstract
Aims: Effects of 3-n-Butylphthalide (NBP) on neuroinflammation in postoperative cognitive dysfunction (POCD) have not been well studied. This study aimed to investigate the effects of NBP treatment on surgery-induced cognitive dysfunction in mice.
Methods: Male C57BL/6 mice, aged ten months, were subjected to tibialfracture surgery while under isoflurane anesthesia in order to mimic orthopedic surgery performed on humans. Tests to assess behavior were conducted at the specified time intervals. We observed structural changes in hippocampal neurons, mitochondria and Golgi apparatus by transmission electron microscopy. The expression levels of IBA1, TNF-α, IL-1β, and apoptotic proteins were determined using Western blot and ELISA.
Results: The results indicated that NBP treatment ameliorates surgery-induced cognitive impairment. Moreover, NBP treatment inhibits microglial activation and reverses neuronal, mitochondrial and Golgi damage in the hippocampus of POCD mice. Furthermore, NBP decreases neuroinflammation in the hippocampus of mice with POCD.
Conclusion: Our research indicates that NBP could be a promising target for therapeutic intervention in POCD.
Deep learning tree and forest biomass from sub-meter resolution images
Authors: Li Sizhuo , Brandt Martin , Tong Xiaoye , Oehmcke Stefan , Igel Christian , Gieseke Fabian , Nord-Larsen Thomas , Fensholt Rasmus , Chave Jerome , Ciais Philippe 
Published: September 2023

Abstract
Computational visual intelligence has been shown to be able to comprehend the content of images, which has been widely used to foster a digitized society, but is often underutilized in applications related to the green transition and climate change mitigation. Here, we evaluate the capacity of convolutional neural networks (CNN) to interpret spatial semantic patterns in optical RGB images to directly estimate forest biomass, an essential climate parameter previously assessed from structural measures of trees. Trained with forest inventory plots, the CNN model demonstrates its learning via interpreting the composition of biomass at tree level, differing from traditional approaches reliant on conversions of aggregated parameters without explanatory rationale. The CNN approach yields consistently low bias across wide biomass ranges, whereas traditional models show insufficiency without information on tree height. Visually interpretable models link advanced computational tools with the power of data, facilitating the sustainable management of resources for a carbon-neutral society.
Effect of Zn Content and SPS Process Parameters on the Microstructure and Hardness of Mg-Zn Alloys
Authors: Hashemi Seyed Mahdi , Hosseinpour Mehrnoosh , Salehi Fatemeh , Jafari Hassan , Parvizi Soroush 
Published: September 2023

Abstract
This research investigated the microstructure and hardness of binary Mg-xZn (x=1, 3, 5) alloys produced by the spark plasma sintering process at different temperatures, times, and pressures. Taguchi quality function was used to model the process and obtain the optimal input parameters. Optical and scanning electron microscopes were used to analyze the microstructure and grain size of the alloys. Microstructural analyses revealed that the grain sizes directly increased by the Zn content. Meanwhile, the intermetallic phase of MgZn was formed in the alloys containing 3 and 5 wt. % Zn. Density and hardness measurements were employed for all alloys. The results also indicated that the highest hardness value was 92.5 HV for the alloy containing 1 wt. % Zn, while the highest relative density, 1.21, referred to the alloy containing 5 wt. % Zn, when the temperature, time, and applied pressure had the minimum values. Furthermore, by increasing temperature and pressure, the porosities were reduced. The grain size initially dropped and then ascended by merging the grains to form larger ones due to the enhanced diffusion kinetics.
Patterns of information literacy and their predictors among emergency department nurses: a latent profile analysis based on the Person-Context interaction theory
Authors: Wu Chao , He Chunyan , Yan Jiaran , Du Juan , He Shizhe , Ji Zhaohua , Wang Yifei , Lang Hong-juan 
Published: September 2023

Abstract
Aim To clarify the subtypes of information literacy among nurses in the emergency department and explore the factors affecting profile membership. Methods A cross-sectional study was conducted among a convenience sample of 2490 nurses in the emergency department from April to June 2023. The clinical nurses completed the online self-report questionnaires including the general demographic questionnaire, information literacy scale, self-efficacy scale and social support scale. Data analyses consisted of latent profile analysis, variance analysis, Chi-square test and multivariate logistic regression. Results Four latent profiles were identified: ‘Low information literacy (Class 1)’, ‘Moderate information knowledge (Class 2)’, ‘High information knowledge and support (Class 3)’ and ‘High information literacy (Class 4)’, accounting for 20.14%, 42.11%, 23.36% and 14.39%, respectively. Different information literacy patterns have different characteristics. Age, years of work, place of residence, hospital grade, title, professional knowledge, using databases, reading medical literature, participating in information literacy training, self-efficacy, and social support significantly predicted information literacy profile membership. Conclusions Information literacy has different classification features among emergency department nurses, and over half of the nurses surveyed were at the lower or middle level. Identifying sociodemographic and internal-external predictors of profile membership may be useful for preparing interventions that will be better suited to emergency department nurses’ needs. Nursing managers should actively pay attention to nurses with low information literacy and help them improve their information literacy level. Relevance to clinical practice Insights from the current study of the latent profile analysis are beneficial to hospital managers in understanding the different types of emergency department nurses' information literacy and provide a reference for them to improve nurses’ information literacy levels.
Ultrasound-guided disc pain induction test for diagnosis of discogenic lumbar pain: A cross-sectional study
Authors: Masuda Keisuke , Shigematsu Hideki , Maeda Manabu , Tanaka Masato , Okuda Akinori , Kawasaki Sachiko , Suga Yuma , Yamamoto Yusuke , Tanaka Yasuhito 
Published: September 2023

Abstract
Background: Several methods can be used to diagnose discogenic pain, but only discoblock can diagnose discogenic pain definitively. This study aimed to examine the usefulness of an ultrasound-guided disc pain induction test for a simple and accurate diagnosis of the culprit lesion.
Methods: We included 41 patients with lumbar pain in whom pain was induced by an ultrasound-guided disc pain induction test. All patients had confirmed pain at L1/2 to L5/S1 based on an ultrasound-guided disc pain induction test and underwent X-ray photography and magnetic resonance imaging. Seventeen patients who required injection due to severe pain underwent discoblock procedures for discs with the most intense pain, and visual analog scale (VAS) scores were obtained before and after the procedure for these patients. We analyzed the association between painful discs and radiological findings.
Results: Pain induction was noted in a total of 65 discs, and the pain was induced in 23 patients in only one disc. All patients had disc degeneration of Pfirrmann classification grade 1 or higher, with more significant disc degeneration in painful discs than in painless discs. There was no significant relationship between the presence or absence of pain and Modic type.
The average VAS measurements improved significantly from 9.5 (pre-procedure) to 2.5 (post-procedure). These results suggest that the most painful discs were the causes of discogenic lumbar pain.
Conclusions: Our ultrasound-guided disc pain induction test may help diagnose disc degeneration and identify culprit lesions, even when multiple discs exhibit findings of degeneration.
Molecular epidemiology of carbapenem and colistin resistant Acinetobacter baumanii
Authors: Rout Bidyut Prava , Dash Sumesh Kumar , Otta Sarita , Behera Birasen , Praharaj Ira , Sahu Kundan Kumar 
Published: September 2023

Abstract
Introduction- Acinetobacter baumanii (AB) is a bacterium of concern in the hospital set up due to its ability to thrive in unfavorable conditions as well as rapid emergence of antibiotic resistance. Carbapenem resistance in this organism is disheartening which is further clouded by emergence of colistin resistance.
Aim- The present prospective study aims to note the epidemiology, molecular profile, and clinical outcome of patients with colistin resistance ABinfections in a multispecialty tertiary care set up in Odisha in Eastern India.
Methods- All AB strains received from March 2021 to February 2022 as identified by Vitek2, Biomerieux and confirmed by oxa-51 genes were included. Carbapenem and colistin resistance was identified as per CLSI guidelines. Known mutations for blaOXA-23-like, blaIMP, blaVIM, blaKP, lpxA, lpxC, pmrA, pmrB and plasmid mediated mcr (mcr1-5) were screened by conventional PCR techniques. The clinical outcome was noted retrospectively from case sheets. Data was entered in excel and tabulated using SPSS software.
Results- In the study period, 350 AB were obtained of which 317(90.5%) were carbapenem resistant (CRAB). Among the CRAB isolates 19 (5.9%) were colistin resistant (CR). Most useful antibiotics in the study were tigecycline (65.4% in CI; 31.6% in CR) and minocycline (44.3% in CI; 36.8% in CR). There was significant difference in mortality among ABCoI and ABCoR infections.bla OXA was the predominant cerbapenem resistance genotype while pmrA was the predominant colistin resistant genotype. There were no plasmid mediated mcr genes detected in the present study.
Screening of Drinking Water for Contamination Diarrhoeal Disease Prevalence Among Children Below the Age of Five in Kaduna Metropolis, Kaduna State, Nigeria
Authors: MALGWI DORIS , MALGWI CHARITY , ADOGU PROSPER , NWOKO DEBORAH 
Published: September 2023

Abstract
Access to water supply and sanitation facilities has considerable health and economic benefits for households and individuals. However, lack of access to safe drinking water and inadequate disposal of human excreta is associated with various diseases, including diarrhoea; diarrhoea is the second leading cause of under-five mortality in developing countries and Nigeria in particular. Microbiological water quality is usually assessed by the identification of Escherichia coli (E. coli), a fecal indicator. The hydrogen sulfide (H2S) test is an inexpensive, easy-to-use, and portable alternative field-based water quality test. This study aims to screen drinking water for contamination and prevalence of diarrhoeal diseases among children below five years of age in kaduna metropolis, kaduna state, Nigeria. A descriptive cross-sectional study involving 180 participants was carried out using a Modified WHO cluster sampling technique; semi-structured questionnaires were used to record bio-data and information in line with the objective of the study, drinking water from various sources were collected in orlab Hydrogen sulphide test vials, stored in an ambient temperature of about 25 ⁰ C – 35 0 C for 24hrs to confirm for blackening of water in the vial to identify faecal contamination. The prevalence of diarrhoea was 40.6% in all four local government areas that make up the Kaduna metropolis; 52.8% of the collected samples tested positive for bacteriological contamination using the test kit. 51.6% of the recorded positive test samples were obtained from employed mothers, 32.6% from unemployed mothers, and 15.8% from self-employed mothers. The mother's age was positively associated (p-value 0.00001 significant), the level of the mother's education (p value = 0.000915 significant), source of drinking water also showed a significant association (p-value 0.00001 significant). A high percentage of prevalence, knowledge, contaminated samples were observed. Also, all sociodemographic factors except religion and sex of child are positively associated with diarrhoea diseases.
Concession of airport clusters in Brazil: analysis of operators’ option to capture consumer surpluses
Authors: Oliveira Márcio Pacelli , Pompermayer Fabiano Mezadre , Sobrinho Edson Silveira 
Published: September 2023

Abstract
The presence of competing airports in the same concession cluster enables an environment conducing the capture of consumer surplus by the private operator, who seeks profit and can force demand to be diverted from the smaller, loss-making airport, to the larger and profitable airport. The Brazilian model airport concessions in clusters apparently does not consider the risks of loss of well-being for society and gains from producer surpluses for airports operating in regions with overlapping catchment areas, as in the case of airports in Curitiba, in Paraná, and Joinville, in Santa Catarina, 120 km apart. To assess the effects of the smaller airport’s closure this article carried out the socioeconomic analysis costs and benefits (CBA) and estimated the cost structure of the airports, their demand curves and the result of the joint operation, in addition to the variation in the loss of consumer surplus. For the consumer, the closure of the smaller airport is not interesting given the magnitude of the loss of surplus verified. From a regulatory point of view, preventing or remedying opportunistic actions by the concessionaire is a problem, given the asymmetry of information existing between the regulator and the regulated one.
Integrating transcriptomics, glycomics and glycoproteomics to characterize hepatitis B virus-associated hepatocellular carcinoma
Authors: Li Zhuo , Zhang Na , Dong Zewen , Wang Xin , Zhou Jian , Gao Juan , Yang Yunyun , Li Jing , Guan Feng , Tan Zengqi 
Published: September 2023

Abstract
Background Hepatocellular carcinoma (HCC) ranks as the third most common cause of cancer related death globally, representing a substantial challenge to global healthcare systems. In China, the primary risk factor for HCC is the hepatitis B virus (HBV). Aberrant serum glycoconjugate levels have long been linked to the progression of HBV-associated HCC (HBV-HCC). Nevertheless, few study systematically explored the dysregulation of glycoconjugates in the progression of HBV-associated HCC and their potency as the diagnostic and prognostic biomarker.Methods An integrated strategy that combined transcriptomics, glycomics, and glycoproteomics was employed to comprehensively investigate the dynamic alterations in glyco-genes, N-glycans, and glycoproteins in the initiation and development of HBV- HCC.Results Bioinformatic analysis of Gene Expression Omnibus (GEO) datasets uncovered dysregulation of fucosyltransferases (FUTs) in liver tissues from HCC patients compared to adjacent tissues. Glycomic analysis indicated an elevated level of fucosylated N-glycans, especially a progressive increase in fucosylation levels on IGHA1 and IGHG2 determined by glycoproteomic analysis.Conclusions The findings indicate that the abnormal fucosylation plays a pivotal role in the progression of HBV-HCC. Systematic and integrative multi-omic analysis is anticipated to facilitate the discovery of aberrant glycoconjugates in tumor progression.