bluuebunny/crossref_metadata_2025_split huggingface dataset:
Аналіз перебігу госпітального періоду захворювання в пацієнтів з невідкладною серцево-судинною патологією та супутньою інфекцією СOVID-19: реєстр одного центру
Authors: Lutay Ya. M. , Parkhomenko O. M. , Khomyakov D. V. , Irkin O. I. , Kushnir S. P. , Kornatskyi Yu. V. 
Published: January 2023

The aim – to analyze in-hospital mortality in pts with acute cardiovascular pathology (ACP) and a co-infection with COVID-19.Materials and methods. 139 pts with ACP who were diagnosed with COVID-19 were examined. 69 (49.6 %) pts had ACS (47 pts with AMI), 33 (23.7 %) pts – hypertensive urgency, 24 (17.3 %) pts – ADHF, 9 (6.5 %) pts – tachysystolic paroxysm of atrial fibrillation, 2 (1.4 %) pts – acute pulmonary embolism, and 2 (1.4 %) pts – syncope. The average age was 67.9±12.7 y.o., 70 (50.4 %) pts were male. Concomitant arterial hypertension was found in 87.1 %, DM – 20.9 %, CHF – 30.9 %, COPD – 9.4 % of pts, history of AMI – 20.1 % and ischemic stroke – 9.4 % of pts. In 79 (56.8 %) pts COVID-19 was diagnosed and laboratory confirmed before hospitalization (hospitalized in 5.3±3.6 days after symptoms onset). 31 (22.3 %) pts were diagnosed with COVID-19 upon admission, and 29 (20.9 %) – during their stay in the hospital. 20 (15.6 %) pts were vaccinated against COVID-19. The initial SpO2 level was 91.6±10.3 %, while more than half of pts (53.2 %) had SpO2 < 95 % and almost every fourth (23.2 %) patient had SpO2 < 90 %.Results and discussion. During the hospital period, 20 (14.4 %) pts died. The mortality rate was 28.0 % in pts with ADHF, 19.1 % in pts with AMI and significantly less in pts hospitalized for unstable angina, hypertensive urgency or atrial fibrillation – 5.2 % (p<0.05 in comparison with pts with AMI or ADHF). The main cause of death was the development of cardiopulmonary failure – 14 (70.0 %) pts. 4 (20.0 %) pts died from AMI complications, 1 – from pulmonary embolism and 1 – from acute ischemic stroke. Two critical periods of in-hospital mortality can be distinguished: 1 – the first two days of hospitalization (mainly complications of acute cardiovascular pathology and thrombotic events); 2 – from 7 to 10 days after hospitalization (development of multiple organ failure due to hypoxia and heart failure progression). The mortality rate of patients with ACP and COVID-19 was significantly higher than that of simultaneously hospitalized patients without comorbid respiratory infection (14.4 % vs. 6.4 %, p=0.012) and patients who were hospitalized before the pandemic (14.4 % vs. 2.9 %, p<0.001). Vaccinated patients were significantly less likely to develop acute kidney injury, acute hypoxic delirium, had higher average blood SpO2, and less often required non-invasive ventilation. Only 1 vaccinated patient died from the development of cardiogenic shock against the background of anterior AMI and multivessel coronary artery disease (mortality – 15.7 % in unvaccinated pts vs 5.0 % in vaccinated, p=0.076).Conclusions. Co-infection with COVID-19 worsens treatment outcomes and in-hospital mortality of patients with ACP. Vaccination significantly reduces the likelihood of complications and tends to reduce mortality.
Mix design programming for normal concrete using cubic equation
Authors: Baggio Eugene Yudhistira , Bagio Toni Hartono , Tistogondo Julistyana 
Published: January 2023

<p>A computer programming requires inputs and processes to produce output, good data processing requires a formula, in programming when using tables is very inefficient, so an approach is needed in this case the existing table tables are converted into formulas, making it easier to process programming. Mix Design for normal concrete, in general, always use tables that have SNI (ACI), the tables are modified with Polynomial Regression to be equations, tables in SNI (ACI) that are transformed into equations. The equation produced, using polynomial regression, with a value of R² ≈ 1. The equation to find weight of mixing water (Ww) = y1j, y2j, with main variable aggregate maximum, additional variables are slump, the second equation is volume air content (VAC) = y3i, additional variables are exposures, water cement ratio (WCR) = y4i, with aggregate maximum variables, while additional variables are air requirements in concrete (non-air entrained/air entrained),weight of coarse aggregate (WCA) = y5i, with two variables aggregate maximum and FM (Finest Modulus), and initial estimates of fresh concrete weight (WFC) = y6i</p>
Family Empowerment In Efforts To Prevent And Overcome Anemia In Pregnant Women
Authors: Tutik Hidayati Tutik Hidayati , Riska Faraswati  
Published: January 2023

Seorang wanita hamil akan mengalami peningkatan volume darah, hal ini menyebabkan kebutuhan akan zat besi juga meningkat. Berdasarkan data remat berkembang Association of southeast Asian Nations (ASEAN) angka kejadian anemia pada ibu hamil diperkirakan antara 20-89% dan angka kejadian anemia tertinggi di Indonesia sekitar 70%. Anemia memiliki dampak pada ibu hamil dan bayi yang akan dilahirkan. Anemia pada ibu hamil dapat menyebabkan abortus, kurang tenaga saat melahirkan, kelahiran premature, BBLR, serta janin mengalami kekurangan gizi saat dalam kandungan dan bisa juga terjadi cacat bawaan terhadap bayinya. Pengabdian Masyarakat ini bertujuan untuk meningkatkan pemberdayaan keluarga dalam mencegah dan menanggulangi anemia. Pemberdayaan ini di ikuti 34 orang dan dilakukan dengan membekali keluarga terlebih dahulu dengan pengetahuan mengenai masalah dan besaran masalah anemia, dampak anemia, faktor penyebab, menu makanan pencegahan anemia dan tablet tambah darah. Tahap selanjutnya adalah mendampingi keluarga dalam mengaplikasikan mencegah dan menanggulangi anemia dengan pemberian kacang hijau. Berdasarkan hasil pengabdian didapatkan bahwa ada peningkatan pengetahuan tentang anemia pada keluarga. Hasil observasi menunjukkan adanya peningkatan rata-rata pengetahuan keluarga antara pre test dan post test dengan pemberian kacang hijau pada ibu hamil untuk mencegah dan menanggulagi anemia.Disarankan ibu hamil untuk meningkatkan asupan zat besi melalui makanan dalam mencegahan anemia
Assistance School Program Sman 02 Batu: Through The Pancasila Student Profile Strengthening Project (P5) In Health Promotion
Authors: Nur Melizza  , Dwi Kurnia Anggraini , Lailatul Masruroh Nur , Hariyati Sri , Hardianti  , Ridwan Muhammad , Nopy Ruthmitasai Ade , Nursanti Ingga 
Published: January 2023

Profil Pelajar Pancasila dirancang untuk menjawab satu pertanyaan besar, yaitu “Pelajar dengan profil (kompetensi) seperti apa yang ingin dihasilkan oleh sistem Pendidikan Indonesia?”. Pernyataan ini berkaitan dengan dua hal, yaitu kompetensi untuk menjadi warga negara Indonesia yang demokratis dan untuk menjadi manusia unggul dan produktif di Abad ke-21. Projek penguatan Profil Pelajar Pancasila memberikan kesempatan kepada peserta didik untuk “mengalami pengetahuan” sebagai proses penguatan karakter sekaligus kesempatan untuk belajar dari lingkungan sekitarnya. Dalam kegiatan projek ini, peserta didik memiliki kesempatan untuk mempelajari tema-tema atau isu penting seperti perubahan iklim, antiradikalisme, kesehatan mental, budaya, wirausaha, teknologi, dan kehidupan berdemokrasi sehingga peserta didik bisa melakukan aksi nyata dalam menjawab isu-isu tersebut sesuai dengan tahapan belajar dan kebutuhannya. Tujuan dari pengabdian ini adalah untuk memberikan pelatihan dan pendampingan kepada siswa dalam mempersiapkan dan melakukan promosi Kesehatan. Metode pelaksanaan pengabdian masyarakat ini berupa penyuluhan, demonstrasi dan diskusi yang dilaksanakan secara luring atau tatap muka. Kegiatan ini terdiri dari 2 sesi, pada sesi 1 materi yang disampaikan adalah cuci tangan, oral hygiene, bullying, kesehatan reproduksi, serta penyusunan satuan acara penyuluhan (SAP). Kemudian, pada sesi kedua dilakukan penguatan informasi terkait materi yang telah diberikan. Hasil kegiatan ini adalah berupa peningkatan pengetahuan terkait materi cuci tangan, oral hygiene, bullying, kesehatan reproduksi, serta penyusunan satuan acara penyuluhan (SAP). Hasil menunjukkan untuk pretest dengn kategori kurang sebanyak 12,5%, cukup 16,7%, baik 70,8%. Pada posttest pengetahuan peserta meningkat menjadi kategori kurang menurun menjadi 8,3%, cukup menurun menjadi 12,5%, dan baik meningkat menjadi 79,2%
OF CHAMPOR ON SEVERAL RICE SEED VARIETIES (Oryza sativa L.) AND THEIR EFFECTS ON MORTALITY IN SEED POWDER PESTS (Rizhopertha dominica
Authors: Nayogi Fendy , Suharjono Suharjono 
Published: January 2023

Penelitian ini bertujuan untuk mengetahui efektivitas champor dengan bahan aktif Naftalen terhadap mortalitas hama Rizhopertha dominica hama serbuk biji dan pengaruh varietas terhadap intensitas serangan hama gudang Rizhopertha dominica dan pengaruh varietas terhadap intensitas serangan. Penelitian dilakukan dengan menggunakan Rancangan Acak Lengkap Faktorial (RAL) dengan 3 ulangan dan 24 kombinasi. Faktor pertama adalah dosis kapur barus (C) yang terdiri dari 4 level C1 = 0 mg / 0,5 kg; C2 = 0,5 mg / 0,5 kg; C3 = 1 mg / 0,5 kg; C4 = 1,5 / 0,5 kg. Faktor kedua adalah jenis varietas (V) dengan 3 level, yaitu V1 = Ciherang; V2 = Sintanur; V3 = Situbagendit. Hasil penelitian berdasarkan analisis uji Annova dengan tingkat 5% menyatakan bahwa aplikasi interaksi dengan varietas kapur barus berpengaruh nyata terhadap mortalitas Rizhopertha dominica. Hasil pengujian lebih lanjut Duncan Multiple level 5%, Aplikasi kapur barus dengan nilai mortalitas tertinggi pada level C2 0,5 mg / 0,5 kg benih padi dengan berbeda sangat nyata dari dosis lainnya. Varietas secara signifikan mempengaruhi intensitas serangan hama gudang Rizhopertha dominica dengan intensitas serangan rendah pada varietas V3 Situbagendit, Ciherang V1 dan V2 Sintanur. Varietas secara signifikan mempengaruhi intensitas serangan hama, kombinasi terbaik dari masing-masing faktor pertama dan faktor kedua adalah Ciherang 0,5 mg / 0,5 kg (C2V1); Sintanur dengan dosis 0,5 mg / 0,5 kg (C2V3); Situbagendit dengan dosis 1 mg / 0,5 kg (C3V3).
HUBUNGAN PENGETAHUAN PERSONAL HYGIENE DENGAN KEJADIAN KEPUTIHAN PADA REMAJA PUTRI DI SMA NEGERI 03 KOTA BENGKULU TAHUN 2022
Authors: Herman Cendy peronika , Destariyani Elvi , Yanniarti Sri 
Published: January 2023

Di Indonesia angka keputihan setiap tahunnya selalu meningkat hingga mencapai 70% pada tahun 2018, dan masalah kesehatan reproduksi yang sering terjadi pada masa remaja putri yaitu terjadinya keputihan. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan personal hygiene dengan kejadian keputihan di SMA Negeri 03 Kota Bengkulu Tahun 2022.
Desain penelitian yang digunakan adalah cross sectional. Populasi dalam penelitian ini adalah siswa perempuan kelas XI di SMA Negeri 03 Kota Bengkulu yang diambil secara teknik purposive sampling dan di dapatkan jumlah responden sebanyak 67 siswa. Data dianalisis menggunakan uji chi squeare.
Hasil penelitian menunjukkan dari 67 responden yang mempunyai pengetahuan baik 19 orang (28,4%), responden yang berpengetahuan cukup 21 orang (31,3%) dan responden yang memiliki pengetahuan kurang sebanyak 27 orang (40,3%). Berdasarkan hasil penelitian dari 67 responden yang mengalami keputihan sebanyak 31 orang (46,3%) dan responden yang tidak mengalami keputihan sebanyak 36 orang (53,7%). Berdasarkan hasil analisis Bivariat chi squere menunjukkan ρ= 0,020 (< α= 0,05) hal ini berarti terdapat hubungan antara pengetahuan personal hygiene terhadap kejadian keputihan di SMA Negeri 03 Kota Bengkulu Tahun 2022.
Diharapkan bagi SMA Negeri 03 Kota Bengkulu mampu mengaktifkan lagi kegiatan PIK-R sehingga penyuluhan mengenai pengetahuan personal hygiene bisa terlaksana.

Kata Kunci : pengetahuan personal hygiene dengan kejadian keputihan
Shift in the submucosal microbiome of diseased peri-implant sites after non-surgical mechanical debridement treatment
Authors: Sun Fei , Wei Yiping , Li Siqi , Nie Yong , Wang Cui , Hu Wenjie 
Published: January 2023

ObjectivesThe object of this prospective study was to assess the submucosal microbiome shifts in diseased peri-implant sites after non-surgical mechanical debridement therapy.Materials and methodsSubmucosal plaques were collected from 14 healthy implants and 42 diseased implants before and eight weeks after treatment in this prospective study. Mechanical debridement was performed using titanium curettes, followed by irrigation with 0.2% (w/v) chlorhexidine. Subsequently, 16S rRNA gene sequencing was used to analyze the changes in the submucosal microbiome before and after the non-surgical treatment.ResultsClinical parameters and the submucosal microbiome were statistically comparable before and after mechanical debridement. The Alpha diversity decreased significantly after mechanical debridement. However, the microbial richness varied between the post-treatment and healthy groups. In network analysis, the post-treatment increased the complexity of the network compared to pre-treatment. The relative abundances of some pathogenic species, such as Porphyromonas gingivalis, Tannerella forsythia, Peptostreptococcaceae XIG-6 nodatum, Filifactor alocis, Porphyromonas endodontalis, TM7 sp., and Desulfobulbus sp. HMT 041, decreased significantly following the non-surgical treatment.ConclusionsNon-surgical treatment for peri-implant diseases using mechanical debridement could provide clinical and microbiological benefits. The microbial community profile tended to shift towards a healthy profile, and submucosal dysbiosis was relieved following mechanical debridement.
Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis
Authors: Hong Christin G. , Florida Elizabeth , Li Haiou , Parel Philip M. , Mehta Nehal N. , Sorokin Alexander V. 
Published: January 2023

BackgroundLow-density lipoprotein cholesterol (LDL-C) is an established marker for cardiovascular disease (CVD) and a therapeutic target. Oxidized LDL (oxLDL) is known to be associated with excessive inflammation and abnormal lipoprotein metabolism. Chronic inflammatory diseases confer an elevated risk of premature atherosclerosis and adverse cardiovascular events. Whether oxLDL may serve as a potential biomarker for CVD stratification in populations with chronic inflammatory conditions remains understudied.ObjectiveTo perform a systematic review and meta-analysis evaluating the relationship between oxLDL and CVD (defined by incident CVD events, carotid intima-media thickness, presence of coronary plaque) in patients with chronic inflammatory diseases.MethodsA systematic literature search was performed using studies published between 2000 and 2022 from PubMed, Cochrane Library, Embase (Elsevier), CINHAL (EBSCOhost), Scopus (Elsevier), and Web of Science: Core Collection (Clarivate Analytics) databases on the relationship between oxLDL and cardiovascular risk on inflamed population. The pooled effect size was combined using the random effect model and publication bias was assessed if P &lt; 0.05 for the Egger or Begg test along with the funnel plot test.ResultsA total of three observational studies with 1,060 participants were ultimately included in the final meta-analysis. The results demonstrated that oxLDL is significantly increased in participants with CVD in the setting of chronic inflammatory conditions. This meta-analysis suggests that oxLDL may be a useful biomarker in risk stratifying cardiovascular disease in chronically inflamed patients.
Outcomes of thoracic endovascular aortic repair with fenestrated surgeon-modified stent-graft for type B aortic dissections involving the aortic arch
Authors: Li Xiaoye , Zhang Lei , Song Chao , Zhang Hao , Xia Shibo , Yang Yang , Zhu Longtu , Guo Wenying , Lu Qingsheng 
Published: January 2023

ObjectivesThis retrospective analysis aimed to evaluate the early and midterm outcomes of thoracic endovascular aortic repair (TEVAR) with fenestrated surgeon-modified stent-graft (f-SMSG) for type B aortic dissections (TBAD) involving the aortic arch.MethodsFrom March 2016 to April 2021, 47 consecutive patients were treated using TEVAR with f-SMSG. All patients were diagnosed with TBAD involving the aortic arch.ResultsIn total, 47 patients with TBAD involving the aortic arch were treated with f-SMSGs. There were 21 zone 1 and 26 zone 2 TEVAR, and 65 arteries were revascularized successfully with fenestrations. Technical success was achieved in 46 patients (97.88%). The 30-day estimated survival (± SE) and reintervention was 93.6 ± 1.0% (95% Confidence Interval [CI], 92.6–94.6%) and 91.5 ± 1.2% (95% CI, 90.3–92.7%), respectively. During a median follow-up of 51 months (range, 16–71 months), 1 patient died of rupture of aortic dissection (AD) and 3 patients died of non-aortic-related reasons. Reintervention was performed for four patients, including two patients of type IA entry flow and two patients of type IB entry flow. No occlusion of the supra-aortic trunk was observed. The estimated survival and reintervention (± SE) at 4 years was 88.7 ± 1.4% (95% CI, 87.3–90.1%) and 84.8 ± 1.5% (95% CI, 83.3–86.3%), respectively.ConclusionThoracic endovascular aortic repair with f-SMSG is an alternative treatment option for TBAD involving the aortic arch in high-volume centers.
Evaluation of urban resilience level and analysis of obstacle factors: A case study of Hunan Province, China
Authors: Chen Na , Guo Hongxia , Xiang Hui 
Published: January 2023

Resilient city is an ideal goal and model of urban development proposed in response to today’s complex and dynamic environmental changes. In this study, a resilient city evaluation framework of “social resilience-economic resilience-urban infrastructure and service-urban governance” was built upon the multi-dimensionality of the urban system; the entropy weight method was used to measure the level of urban resilience in Hunan Province while an obstacle degree model was used to identify any obstacle factor restricting to the development of resilience. The results show that the level of urban resilience in Hunan Province has grown slowly over the past 10 years, and there is an obvious regional difference in it. There are more and more highly resilient cities, but medium/low-resilience cities still dominate the province, forming a spatial process of evolution from “medium/high-level dispersion” to “medium/high-level aggregation” in the Changsha-Zhuzhou-Xiangtan Urban Agglomeration. The level of urban resilience is predominantly hindered by the social and economic systems; at the index layer, most obstacle factors are moving from the economic system to the social-economic-urban infrastructure and service system.
Numerical simulation of mechanical compaction and pore evolution of sandstone considering particle breakage
Authors: Jia Tong , Zhang Liqiang , Chen Cai , Wang Zuotao , Yan Yiming , Li Junjian 
Published: January 2023

Mechanical compaction is an important diagenetic process in sandstone reservoirs. Particle breakage, which commonly occurs during mechanical compaction, plays a significant role in controlling the physical properties of the reservoir. However, existing numerical simulation methods have limitations in simulating mechanical compaction when considering particle breakage. In this study, a discrete element simulation method of mechanical compaction was proposed based on particle cutting, and the experimental results reported in the literature were used to calibrate the simulation parameters. Finally, this method was applied to the simulation of the mechanical compaction of sandstone to analyze the pore evolution process. The results show that the new simulation method has high computational efficiency and can reflect the process of particle breakage. The simulation results coincide well with the experimental results. In the simulated mechanical compacted process of coarse sandstone, particle breakage is strong in the high-stress stage with a vertical stress of 30 MPa–50 MPa. The porosity and mean radii of pores and throats decreased rapidly, and the number of pores and throats increased rapidly in the high-stress stage. When the vertical stress reached 50 MPa, compared to the simulation results without considering particle breakage, the porosity difference rate caused by particle breakage was 4.63%; the radius difference rates of pores and throats were 2.78% and 6.8%, and the number difference rates of pores and throats were 4.95% and 8.74%, respectively. In the process of mechanical compaction, the pore evolution of the reservoir is controlled by the filling of the pre-existing pore space by the fragments generated through particle breakage and the generation of microfractures. Additionally, the simulation method presented in this study can be applied to complex geological conditions and can be combined with other reservoir simulation methods. The simulation results can provide rich training samples for artificial intelligence and other emerging technologies.
Study on erosion and stability of the ecological slope
Authors: Tao Hu , Lei Shao-Wei , Gong Li , Shi Xi , Zhang Meng-Meng , Yang Guo-Qiang 
Published: January 2023

Rainfall is the main influencing factor causing slope erosion, landslide, and instability in loess; thus, it is vital to comprehend the process of rainfall erosion on various slope surfaces and water penetration inside the slope. In this paper, the loess sample is from Heifangtai in Gansu Province, and triaxial shear tests were conducted on loess with roots under varying water contents to evaluate the slope-reinforcing impact of roots. The slope surface erosion process was analyzed using a soil moisture sensor and matric suction meter to monitor the variation of matric suction in the middle slope and slope foot in response to varying precipitation levels. The numerical simulation approach is utilized to analyze the fluctuation of slope stability under the effect of varying rainfall intensities and humid heat, and the analytical solution of the safety factor is compared to the model solution. The results indicate that the shortest generation time for bare slope runoff is 6 min, whereas the greatest generation time for the Bermuda grass slope is 12 min; the shorter the period, the less water penetration and the simpler it is to reach the slope erosion stage. The slope’s rise increases runoff velocity, strengthening water resistance on the slope surface. When the test slope is 30°, the maximum mass of scouring sediment on the bare slope is 15.2 g from 24 to 36 min, compared to 14.7 g from 24 to 36 min when the test slope is 60°. The amount of scouring reduces as the slope increases. The slope safety factor declined from 3.51 to 2.84 after 24 h of heavy rain, and the loss rate accelerated as the rainfall intensity increased.