bluuebunny/crossref_metadata_2025_split huggingface dataset:
Additional value of microvascular flow imaging in the assessment of cystic and solid renal lesions
Authors: Járay Ákos , Farkas Péter István , Semjén Dávid , Battyáni István , Botz Bálint 
Published: February 2023

AbstractBackgroundContrast enhanced ultrasound (CEUS) is increasingly used in the evaluation of renal lesions, however, its availability remains limited. Thus, sensitive noncontrast ultrasound evaluation of renal lesion vascularity is an unmet need.MethodsIn this single-center, retrospective study we assessed microvascular flow imaging (MV-flow) compared to CEUS in the evaluation of complex renal cysts and solid lesions. Out of 92 patients 28 were evaluated with both CEUS and MV-flow. Color Doppler, CEUS, and MV-flow was performed in 13 cases, whilst MV-flow, CEUS, and contrast-enhanced MV-flow (CE-MV-flow) was done in 16 cases. The CEUS diagnosis was considered gold standard.ResultsMV-flow showed a substantial agreement with the CEUS diagnosis (weighted Kappa = 0.806), excluding equivocal lesions (Bosniak 2F). MV-flow substantially outperformed color Doppler (weighted Kappa = 0.77 vs. 0.133). The agreement of CE-MV-flow and MV-flow was comparable (weighted Kappa = 0.79 vs. 0.69).ConclusionMV-flow significantly improves evaluation of renal lesion vascularity compared to conventional techniques. However, the sensitivity is limited for equivocal lesions (e.g. Bosniak 2F cysts). Thus, MV-flow should be used as an ancillary technique, not as a substitute to CEUS. Current MV-flow presets are ill-suited for postcontrast imaging, therefore specific presets optimized for this purpose are needed to establish its potential.
Delayed Cardiac Metastasis from Renal Cell Carcinoma Caused by VHL Mutation
Authors: Sudduth Christopher L. , Castagno Anthony , Maggs Peter 
Published: February 2023

Cardiac metastasis caused by renal cell carcinoma (RCC) without vena caval involvement is rare. No mutation has been associated with this unique phenotype. A 77-year-old male presented to our clinic with a symptomatic right ventricular mass after nephrectomy for clear cell RCC (ccRCC). The mass was resected, and metastatic disease was confirmed. Targeted exon sequencing identified a VHL mutation (c.494T > G, p.V165G) in the resected specimen. While more than half of ccRCC cases are associated with VHL mutations, this case is the first to show the association between delayed, isolated cardiac metastasis and VHL V165G mutation. The phenotype presented 12 years after nephrectomy and localized to the right ventricular apex. Further genomic characterization of cases with cardiac metastases may provide clues regarding unique mutations noted. Patients exhibiting delayed spread of RCC to the heart must be screened for this mutation.
Muzeum-Rezerwat „Bitwa pod Stalingradem” – historia i nowoczesność
Authors: Ivanyuk Sergey , Skorchenko Irina 
Published: February 2023

The article is dedicated to issues connected with the foundation and functioning of a leading the Russian museum-outpost – the Museum “The Battle of Stalingrad” in Volgograd. In years 1942–1943 in Volgograd, called Stalingrad at that time, and on its suburbs one of most important battles of World War II took place; for more than five months Red Army, with the huge cost of human losses, beat off the attack of German armies aiming to overtake this strategically important place. Memory about those events is cultivated by the Museum “The Battle of Stalingrad”. The museum is not only a place of constant and temporary exhibitions; it is also a place of educational and informational activity. Everything what is connected with the heroic defence of Stalingrad – the all military equipment, banners, documents, photographs and other souvenirs coming from the period of World War II can be seen in several departments of the museum located in the city; about 2 000 000 people visit the place each year.
Artysta Bolesław Jarosław Cybis: krótki szkic życia i twórczości do 1939 roku wraz z wyborem źródeł
Authors: Żwanko Lubow 
Published: February 2023

A sketch of life of an outstanding, but a little forgotten, artist Bolesław Jarosław Cybis, who lived in years 1895– 1957, is presented in the article, but the author discusses only period till 1939. On the basis of an analyses of materials five stages in his biography have been separated: Crimean-Petersburg (1895–1912), Kharkov (1912–1919), Istanbul (1920–1923), Varsovian (1923–1939) and American (1939–1957). The article has been based on sources that have been unknown so far. The materials are stored in the Archive of Academy of Fine Arts in Warsaw, and they are connected with studies, employment, and the artist’s private life. Special attention has been paid to Kharkov time which became the time of choosing an occupation and also time of avant-garde, a dominating arts movement at that time, which became also his style of creating.
Impact of circuit rhythms disturbances on the clinical picture of the disease in patients with metabolic syndrome
Authors: Gribanov I. A. , Zarubina E. G. 
Published: February 2023

The purpose of this study was to evaluatey the effect of dark deprivation of various durations on the course of the metabolic syndrome (MS).Material and research methods. To achieve this aim, based on WHO criteria, we selected patients with MS and disturbed circadian rhythms – a total of 102 people (all men) from among people who constantly work at night, in whom a decrease in melatonin levels was recorded at a preliminary stage. In accordance with the tasks set, 102 patients (all men) of working age (young age according to WHO criteria) were divided into three groups of 33, 37 and 32 people, respectively, according to the criterion "duration of work at night and duration of history of MS": 0–5, 5–10 and over 10 years. In the first group, the mean age was 30.1 ± 1.4 years; in the second group, the mean age was 36.5 ± 1.5 years; in the third group, the mean age did not exceed 40.3 ± 0.9 years. As a control group, 45 patients with MS were examined, comparable with the main groups in terms of background pathology and age and different duration of MS history.Results. It was found that the main symptom of MS - abdominal type of obesity (waist circumference more than 80 cm for men) was detected in 100% of patients of the main and control groups of observation. At the same time, it was found that the severity of abdominal obesity is combined with an increase in body mass index (BMI) and tends to increase in patients in the main groups, compared with patients from the control group. In the control group, 35.5% of the examined patients had grade 1-2 hypertension, and another 15.6% had elevated normal blood pressure.Conclusions: In patients with MS, against the background of violations of regulatory mechanisms, the disease is more severe than in patients with a similar history of MS, but without violations of circadian rhythms. The severity of the course of MS against the background of a decrease in the level of melatonin increases with the duration of the violation of regulatory mechanisms.
The results of bacterial contamination of dangerous and borderline cases of burns
Authors: Tolstov A. V. , Novikov I. V. , Milyudin E. S. , Yunusov R. R. , Kivaeva O. I. 
Published: February 2023

The aim is to study the microbiological picture of purulent inflammation of superficial local burns in the center of thermal lesions of Samara.Material and methods. The etiological structure of local burn infection was analyzed in 29 patients with limited, borderline burns of I-II degree in all phases of the wound process. The collection of wound material was carried out in accordance with the requirements of the Methodological Guidelines of MU 4.2.2039-05 "Technique of collecting and transporting biomaterials to microbiological laboratories". The material was delivered to the laboratory in test tubes with a transport medium under isothermal conditions at a temperature of 20–22 °C within a day after collection.Results. The analysis of the etiological structure of burn infection showed that staphylococcus (St. aureus, St. warneri, St. gallinarium, St. spp, St. epidermidis) plays a leading role in microbiological examination – in 26 patients (89.6 %) and E. coli (E. coli) in 11 (37.9 %). There were no significant differences in the studied signs in the comparison groups (p > 0.05, p = 0.55, χ2 = 3.841).Conclusion. The obtained results of the etiological structure of purulent inflammation of limited burns are statistically reliable and can be used in the development of antibacterial agents for the treatment of burn infection.
Clavicular Fractures in the Adolescent
Authors: Patel Midhat , Heyworth Benton E. , Dehghan Niloofar , Mehlman Charles T. , McKee Michael D. 
Published: February 2023

➤ Current evidence suggests that the majority of clavicular fractures in adolescents can and should be treated nonoperatively.➤ Although rare, in certain patients or fracture patterns, nonoperative management may be associated with delayed healing, prolonged disability, and/or poor functional outcome requiring secondary reconstruction.➤ When warranted, primary open reduction and internal fixation with plate and screw application has consistently good outcomes with a low complication rate, with the most common complication being implant-related symptoms requiring a secondary surgical procedure for implant removal.➤ Prospective, comparative studies examining operative and nonoperative treatment, including measures of early return to function, injury burden, return to athletic activity, complication and reoperation rates, and shoulder-girdle-specific, long-term outcome measures are warranted to further elucidate which fractures may benefit from primary fixation.
Consecuencias psicosociales de la regulación del cannabis: un estudio cualitativo
Authors: Molina-Fernández Antonio , Medrano Chapinal Paula , Comellas Sanz Pol 
Published: February 2023

Introducción: Las diferentes legalizaciones de uso de cannabis terapéutico y recreativo han intensificado la presencia de este tema en los ámbitos científico, político y social. La regulación del consumo de cannabis recreativo debería tener en cuenta cuáles pueden ser sus consecuencias psicosociales y los enfoques utilizados. El estudio de dichas consecuencias psicosociales es el principal objetivo de esta investigación. Método: Metodología cualitativa: revisión bibliográfica y entrevistas a expertos, con diseño de investigación-acción. Resultados: La regulación debe plantearse desde un enfoque de salud pública y derechos humanos, no desde posturas socioeconómicas o de libertades individuales. Las consecuencias para la población general se integran sobre todo la salud mental y los accidentes, tanto laborales como de tráfico. El principal grupo de riesgo son los jóvenes, especialmente la combinación de fracaso escolar, dificultades en el ámbito laboral y el descenso del riesgo percibido del consumo de cannabis. La respuesta ante una regulación debe ser proporcional, estructurada y con acciones desde la prevención e intervención temprana. Conclusiones: contemplar el impacto psicológico sobre la salud mental de los consumidores. Se señala el problema que representa la ineficacia de los programas actuales de prevención y tratamiento para los consumidores de cannabis de riesgo.
“Sir, you’re hurting me!”: The perspectives of survivors of interpersonal violence and breast cancer
Authors: Simon-Plumb Casey Lu , Hamdan Kate , Fikre Tsion , Singerman Amanda , Bair-Merritt Megan , Rothman Emily F. , Ko Naomi Y. 
Published: February 2023

Abstract
Background
Studies suggest that experiences of interpersonal violence victimization (i.e., partner violence, childhood sexual or physical abuse, and sexual assault) might play a role in breast cancer diagnosis and treatment. To address gaps in knowledge, our study aimed to understand how prior interpersonal trauma affects breast cancer. We conducted 20 semi-structured in-person interviews and asked patients how their interpersonal trauma affected their breast cancer experience and if they had suggestions to improve breast cancer care.
Methods
Patients were recruited through flyers or from providers to whom they had previously disclosed a history of interpersonal violence. One-on-one interviews lasted approximately one hour each. Results were thematically coded in an iterative fashion and analyzed for main themes.
Results
Three themes addressed the relatedness of interpersonal violence and cancer care: 1) perceptions that violence caused the cancer or led to worse outcomes, 2) how breast cancer diagnosis and treatment can trigger interpersonal violence memory (triggers), and 3) difficulty trusting. In addition, three suggestions emerged that related to improving care: the importance of female providers, improved provider communication, and the potential benefits of a buddy system to pair newly diagnosed breast cancer patients with a history of interpersonal violence with breast cancer survivors with a similar background.
Conclusion
Interpersonal violence can influence how women feel about their breast cancer diagnoses, interactions with health care providers, and receiving care for cancer. Improving trauma-informed health care practice would be beneficial for women with breast cancer.
Electronic health records to capture primary outcome measures: two case studies in HIV prevention research
Authors: Dunn David , McCabe Leanne , White Ellen , Delpech Valerie , Kirwan Peter , Khawam Jameel , Croxford Sara , Ward Denise , Brodnicki Elizabeth , Rodger Alison , McCormack Sheena 
Published: February 2023

Abstract
Background

There is increasing interest in the use of electronic health records (EHRs) to improve the efficiency and cost-effectiveness of clinical trials, including the capture of outcome measures.

Main Text

We describe our experience of using EHRs to capture the primary outcome measure – HIV infection or the diagnosis of HIV infection – in two randomised HIV prevention trials conducted in the UK. PROUD was a clinic-based trial evaluating pre-exposure prophylaxis (PrEP), and SELPHI was an internet-based trial evaluating HIV self-testing kits. The EHR was the national database of HIV diagnoses in the UK, curated by the UK Health Security Agency (UKHSA). In PROUD, linkage to the UKHSA database was performed at the end of the trial, and identified five primary outcomes in addition to the 30 outcomes diagnosed by the participating clinics. Linkage also produced an additional 345 person-years follow-up, an increase of 27% over clinic-based follow-up. In SELPHI, new HIV diagnoses were identified either by participant self-report (through internet surveys) or via UKHSA linkage. Rates of survey completion were low, and only 14 of the 33 new diagnoses recorded in the UKHSA database were also self-reported. Thus UKHSA linkage was essential for capturing HIV diagnoses and therefore the successful conduct of the trial.

Conclusions

Our experience of using the UKHSA database of HIV diagnoses as a source of primary outcomes in two randomised trials in HIV prevention was highly favourable, and encourages the use of a similar approach in future trials in this disease area.
Impact of Neurofibromatosis Type 1 on Quality of Life Using the Skindex-29 Questionnaire Quality of Life in Nf1
Authors: Rivera Ana M. Cieza , Fuertes Carlos Lobato , Fernández-Villa Tania , Martín Vicente , Atallah Isis 
Published: February 2023

Abstract
Background: Neurofibromatosis type 1 (NF1) is the most common genodermatose which predisposed affected patients to melanic lesions and benign tumors. NF1 is associated with considerable esthetic and functional burden affecting negatively patients’ quality of life (QoL). This study aims to assess the clinical features of NF1 patients and evaluate their impact on QoL. NF1 patients were identified from a public health database of a region in Spain. All patients underwent clinical and ophthalmological evaluation for NF1 features. QoL was measured with the Spanish version of the Skindex-29. Logistic regression was performed to determine the factors associated with quality of life.
Results: Fourty patients fulfilling NF1 National Institute of Health criteria were recruited (40.95 years ± 16.1 SD). The mean total Skindex-29 score was 14 ± 11 (emotion: 20 ±18, symptoms 10±11, functioning 9±10).Woman, NF1 patients with lower educational level or macrocephaly were associated with poorer quality of life scores. Itching, headaches and sleep troubles were identified to negatively influence quality of life of NF1 patients.
Conclusion: NF1 considerably influences the psychological well-being of NF1 patients. We observed that female patients, low-educated patients and macrocephalic patients scored higher on the emotional dimension of the skindex-29 and could therefore be more at risk of depression. We also pointed out some “minor symptoms” that negatively impacts NF1 patients QoL such as itching, sleep troubles or headache which could be treated if seek by doctors.
Synthetic Aperture Sensing for Occlusion Removal with Drone Swarms
Authors: Nathan Rakesh John Amala Arokia , Kurmi Indrajit , Bimber Oliver 
Published: February 2023

Abstract
We demonstrate how efficient autonomous drone swarms can be in detecting and tracking occluded targets in densely forested areas, such as lost people during search and rescue missions. Exploration and optimization of local viewing conditions, such as occlusion density and target view obliqueness, provide much faster and much more reliable results than previous, blind sampling strategies that are based on pre-defined waypoints. An adapted real-time particle swarm optimization and a new objective function are presented that are able to deal with dynamic and highly random through-foliage conditions. Synthetic aperture sensing is our fundamental sampling principle, and drone swarms are employed to approximate the optical signals of extremely wide and adaptable airborne lenses.
Janus Porous Polylactic Acid Membranes with Versatile Metal-Phenolic Interface for Biomimetic Periodontal Bone Regeneration
Authors: Li Jianhua , Ge Shaohua , Zhang Yaping , Chen Yi , Ding Tian , Zhang Yandi , Yang Daiwei , Zhao Yajun , Liu Jin , Ma Baojin , Bianco Alberto 
Published: February 2023

Abstract
Conventional treatment to periodontal and many other bone defects requires the use of barrier membranes to guided tissue regeneration (GTR) and guided bone regeneration (GBR). However, current barrier membranes normally lack of the ability to actively regulate the bone repairing process. Herein, we proposed a biomimetic bone tissue engineering strategy enabled by a new type of Janus porous polylactic acid membrane (PLAM), which was fabricated by combining unidirectional evaporation-induced pore formation with subsequent self-assembly of a bioactive metal-phenolic network (MPN) nanointerface. The prepared PLAM-MPN simultaneously possesses barrier function on the dense side and bone-forming function on the porous side. In vitro, the presence of MPN nanointerface potently alleviated the proinflammatory polarization of rat bone marrow-derived macrophages (BMDMs), induced angiogenesis of human umbilical vein endothelial cells (HUVECs), and enhanced the attachment, migration and osteogenic differentiation of periodontal ligament stem cells (PDLSCs). The implantation of PLAM-MPN into rat periodontal bone defects remarkably enhanced bone regeneration. This bioactive MPN nanointerface within a Janus porous membrane possesses versatile capacities to regulate cell physiology favoring bone regeneration, demonstrating great potential as GTR and GBR membranes for clinical applications.
Performance analysis of vacation interruption queue with balking and reneging
Authors: Majid Shakir , Vijaya Laxmi Pikkala , Angelika Bouchentouf Amina , M Aijaz 
Published: February 2023

Abstract
This paper presents a comprehensive study of an infinite buffer M/M/1 queue with variant working vacations subjected to Bernoulli schedule vacation interruption wherein the customers balk with a probability. The server commences a working vacation as soon as the system becomes empty and resumes a regular busy period by interrupting the working vacation with probability 1 − p if the system is non-empty at a service completion instant or continues the vacation with probability p. The customers may renege due to slow service rate during the working vacation. The inter-arrival times, service times (both during regular busy period and working vacation periods), vacation times and reneging times are mutually independent and exponentially distributed. We derive the probability generating function of the steady-state probabilities and obtain the closed form expressions of the system size for different server states. Various performance measures and the monotonicity on some performance measures with respect to K are discussed, and a cost optimization problem through quadratic fit search method has been considered. The stochastic decomposition structures of the mean queue length and mean waiting time are verified.
Mathematics Subject Classification (2000) 60K25 · 68M20 · 90B22
A Practical Approach for Employing Tensor Train Decomposition in Edge Devices
Authors: Kokhazadeh Milad , Keramidas Georgios , Kelefouras Vasilios , Stamoulis Iakovos 
Published: February 2023

Abstract
Deep Neural Networks (DNN) have made significant advances in various fields including speech recognition and image processing. Typically, modern DNNs are both compute and memory intensive, therefore their deployment in low-end devices is a challenging task. A well-known technique to address this problem is Low-Rank Factorization (LRF), where a weight tensor is approximated by one or more lower-rank tensors, reducing both the memory size and the number of executed tensor operations.
However, the employment of LRF is a multi-parametric optimization process involving a huge design space where different design points represent different solutions trading-off the number of FLOPs, the memory size, and the prediction accuracy of the DNN models. As a result, extracting an efficient solution is a complex and time-consuming process. In this work a new methodology is presented that formulates the LRF problem as a (FLOPs vs. memory vs. prediction accuracy) Design Space Exploration (DSE) problem. Then, the DSE space is drastically pruned by removing inefficient solutions. Our experimental results prove that the design space can be efficiently pruned, therefore extract only a limited set of solutions with improved accuracy, memory, and FLOPs compared to the original (non-factorized) model. Our methodology has been developed as a stand-alone, parameterized module integrated into T3F library of TensorFlow 2.X.
WITHDRAWN: Non-interference patterns evolving to orthogonal interference patterns in same wave experiment
Authors: Peng Hui 
Published: February 2023

Abstract

Young’s double slit experiments revived the wave theory of light. The interpretation is that light behaves as waves before and after passing through the double slit. In this article, we study the evolution of the patterns of the wave experiments. The experiments show the novel universal phenomena: (1) Within a certain macroscopic distance from the diaphragm, light behaves as photons and produces a non-interference pattern; while near the screen, the photons produce an interference pattern; namely the nature and characteristics of the patterns are distance-dependent; (2) The non-interference patterns evolves to the orthogonal interference patterns gradually in the same wave experiment; (3) The convex lens stops the evolution of the patterns at the position where it is placed. We suggest that a complete theory should be able to interpret the non-interference pattern, the interference pattern, and the evolution from one pattern to another.