bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cohort study of postural sway and low back pain: the Copenhagen City Heart Study
Authors: Madsen Anja Lykke , Gyntelberg Finn , Marott Jacob Louis , Schnohr Peter , Astrup Jens 
Published: September 2023

Abstract
Purpose
Low back pain is a significant health problem with a high prevalence. Studies of smaller cohorts of low back pain patients have indicated increased body sway. The present paper tests the hypothesis of an association between low back pain and postural sway in a large randomly selected population.

Methods
The current study used the fifth examination (2011–2015) of The Copenhagen City Heart Study where 4543 participated. The participants answered a self-administered questionnaire regarding pain, physical activity, smoking, alcohol consumption, education, and other lifestyle factors. Measurement of postural body sway was performed using the CATSYS system.

Results
Totally 1134 participants (25%) reported to have low back pain. Subjects with low back pain had higher sway area and sway velocity than subjects without.

Conclusion
When using multivariate statistical analysis, confounding factors such as male gender, higher age, larger body height, low education level, smoking, and low activity level explained the association between low back pain and postural sway.
Clinical evaluation of sodium hypochlorite/amino acids and cross-linked hyaluronic acid adjunctive to non-surgical periodontal treatment: a randomized controlled clinical trial
Authors: Ramanauskaite Egle , Machiulskiene Vita , Shirakata Yoshinori , Dvyliene Urte Marija , Nedzelskiene Irena , Sculean Anton 
Published: September 2023

Abstract
Objectives
To compare the clinical outcomes obtained with either mechanical subgingival debridement in conjunction with a sodium hypochlorite and amino acids containing gel followed by subsequent application of a cross-linked hyaluronic acid gel (xHyA) gel, or with mechanical debridement alone.

Materials and Methods
Fourty-eight patients diagnosed with stages II-III (Grades A/B) generalised periodontitis were randomly treated with either scaling and root planing (SRP) (control) or SRP plus adjunctive sodium hypochlorite/amino acid and xHyA gels (test). The primary outcome variable was reduction of probing depth (PD), while changes in clinical attachment level (CAL), bleeding on probing (BOP) and plaque index (PI) were secondary outcomes. The outcomes were assessed at baseline, at 3 and 6 months following therapy.

Results
All patients completed the 6 months evaluation. At 6 months, the test group showed statistically significantly better results in terms of mean PD reduction (2.9 ± 0.4 vs 1.8 ± 0.6 mm, p < 0.001). Similarly, mean CAL gain was statistically higher in the test group compared to the control one (test: 2.6 ± 0.5 vs control: 1.6 ± 0.6 mm, p < 0.001). Mean BOP decreased from 81.8 ± 16.2% to 48.9 ± 14.5% in control (p < 0.001) and from 83.2 ± 15.5% to 17.6 ± 11.5% in test (p < 0.001) groups with a statistically significant difference favouring the test group (p < 0.001). Mean PI scores were reduced statistically significantly in both groups (from 38.8 ± 26% to 26.5 ± 20.5% in control (p = 0.039) and from 60.6 ± 10.9% to 12.7 ± 8.9% in test group (p < 0.001)), with a statistically significant difference between the groups (p < 0.001). The number of moderate pockets (4–6 mm) were reduced from 1518 (41.2%) to 803 (22.6%) in the control and from 1803 (48.6%) to 234 (7.7%) in the test group with a statistically significant difference between the groups (p < 0.001), while the number of deep pockets (≥ 7 mm) changed from 277 (7.6%) to 35 (1.0%) in the control and from 298 (8.7%) to 4 (0.1%) in test group (p = 0.003).

Conclusion
Within their limits the present data indicate that: a) both treatments resulted in statistically significant improvements in all evaluated clinical parameters, and b) the adjunctive subgingival application of sodium hypochlorite/amino acid and xHyA to SRP yielded statistically significantly higher improvements compared to SRP alone.

Clinical relevance
The combination of sodium hypochlorite/amino acid and xHyA gels to subgingival mechanical debridement appears to represent a valuable approach to additionally improve the outcomes of non-surgical periodontal treatment.
Clinical Trial Registration Number NCT04662216 (ClinicalTrials.gov).
Integrating shallow head measurements and InSAR data to quantify groundwater-storage change in San Joaquin Valley, California (USA)
Authors: Lees M. , Knight R. 
Published: September 2023

AbstractMonitoring groundwater storage is essential for sustainable groundwater management. Storage can be quantified by considering the two main components through which storage change is expressed: saturation changes and deformation of aquifer materials. Here, these components were quantified using a selected area in California’s San Joaquin Valley (USA). First, this involved following existing observational approaches: quantifying the component expressed through saturation changes by identifying head measurements from shallow wells and scaling by specific yield. In the San Joaquin Valley, existing approaches to estimate the deformation component are to ignore it or approximate it with a simple linear relation to measured head. However, head and deformation measurements made at extensometers revealed that assuming a linear relationship between deformation and head might provide a poor estimate, particularly during periods in which measured head is rising. Instead, InSAR-derived surface deformation measurements were used to quantify the deformation component of storage changes. This showed that the two components—saturation and deformation—accounted for storage declines of equal magnitude over 2015–2021, suggesting that the deformation component should not be neglected when estimating storage changes in regions with subsidence. Summing the two calculated components gave a new estimate of the total storage change that captured the major trends seen in independent estimates, while better accounting for the deformation component. An additional benefit is that this method accounts for the deformation component in the unconfined aquifer. This method to quantify total storage change can be a practical and effective tool to support groundwater management.
Disparities in computed tomography utilization for pediatric blunt trauma: a systematic review and meta-analysis comparing pediatric and non-pediatric trauma centers
Authors: Hassankhani Amir , Valizadeh Parya , Amoukhteh Melika , Jannatdoust Payam , Saeedi Nikoo , Sabeghi Paniz , Ghadimi Delaram J. , Johnston Jennifer H. , Gholamrezanezhad Ali 
Published: September 2023

AbstractPediatric blunt trauma is a major cause of morbidity and mortality, and computed tomography (CT) imaging is vital for accurate evaluation and management. Pediatric trauma centers (PTCs) have selective CT practices, while non-PTCs may differ, resulting in potential variations in CT utilization. The objective of this study is to delineate disparities in CT utilization for pediatric blunt trauma patients between PTCs and non-PTCs. A systematic review and meta-analysis were conducted following established guidelines, searching PubMed, Scopus, and Web of Science up to March 3, 2023. All studies examining CT utilization in the management of pediatric (aged < 21 years) blunt trauma and specifying the type of trauma center(s) were included, and data were extracted and analyzed using STATA software version 17.0. An analysis of 30 studies revealed significant variations in CT scan utilization among pediatric blunt trauma patients across different types of trauma centers. PTCs exhibited lower pooled rates of abdominopelvic CT scans (35.4% vs. 44.9%, p < 0.01), cranial CT scans (36.9% vs. 42.9%, p < 0.01), chest CT scans (14.5% vs. 25.4%, p < 0.01), and cervical spine CT scans (23% vs. 45%, p < 0.01) compared to adult or mixed trauma centers (ATCs/MTCs). PTCs had a pooled rate of 54% for receiving at least one CT scan, while ATCs/MTCs had a higher rate of 69.3% (p < 0.05). The studies demonstrated considerable heterogeneity. These findings underscore the need to conduct further research to understand the reasons for the observed variations and to promote appropriate imaging usage, minimize radiation exposure, and encourage collaboration between pediatric and adult trauma centers.
Assessment of exposure to fungi in archives and libraries based on analyses of filter and nasal samples: preliminary investigation
Authors: Cyprowski Marcin , Ławniczek-Wałczyk Anna , Stobnicka-Kupiec Agata , Gołofit-Szymczak Małgorzata , Górny Rafał L. 
Published: September 2023

AbstractThe aim of this study was to characterize the occupational exposure to inhalable dust and airborne fungi among archive and library workers based on qualitative and quantitative analyses of stationary and personal filter samples as well as nasal swabs. The study was carried out in 3 archives and 2 libraries and involved 9 workers of these institutions. Airborne fungi and inhalable dust samples were collected by stationary and personal measurements using filter samplers. Additionally, the nasal swabs from workers were taken after work-shift and microbiologically analysed. The average concentrations of inhalable dust and airborne fungi were 49 µg/m3 (SD = 91) and 299 CFU/m3 (SD = 579), respectively. Both dust and bioaerosol concentrations obtained using personal measurements were significantly higher than that measured by stationary sampling. The correlation analysis showed strong relationships between the concentrations of inhalable dust and airborne fungi (R = 0.57; p < 0.001). The fungal concentrations in swab samples from archive workers (median: 104 CFU/ml) were significantly higher than that in swabs from librarians (median: 1.4 CFU/ml). Among the airborne fungi, the widest spectrum of species was found among Penicillium and Aspergillus (including pathogenic A. fumigatus) genera. However, in samples from archives, yeast-like fungi from Sporidiobolus and Candida (including pathogenic C. albicans) genera predominated among isolated mycobiota. The results of this study revealed that airborne fungi were able to efficiently contaminate the nasal cavity of archive and library employees. The analysis of nasal swabs can be considered as an important analytical tool supporting the assessment of workers’ exposure to bioaerosols.
Virtual Delivery of Parent Coaching Interventions in Early Childhood Mental Health: A Scoping Review
Authors: Hippman Catriona , Mah Janet W. T. , MacFadden Megan 
Published: September 2023

AbstractParent–coaching interventions positively impact child development. Virtual delivery of such interventions is supported by literature reviews and a practice guideline, however, none of these focused on children under age six. A scoping review of virtually-delivered parent-coaching interventions for disruptive behaviour, anxiety, and parent–child relationship concerns in children under age six was conducted between Dec. 15, 2020 and April 22, 2021. Iterative searches of the databases PubMed, CINAHL, and PsycINFO were complemented by reference list searches and clinician expert review (N = 1146). After relevance screening and duplicate removal, collaboratively-developed inclusion criteria were applied to records, followed by data extraction from eligible articles (n = 30). Most literature documented behavioural-based interventions targeting disruptive behaviour which were delivered individually, by therapists, to White, non-Hispanic parents. Evidence supports feasibility and efficacy of virtually-delivered parent-coaching interventions to improve child disruptive behaviour (strong), anxiety (moderate), and parent–child relationship (weak). There is a significant gap in the literature regarding the virtual delivery of attachment-based parent-coaching interventions. In sum, virtual parent coaching can be an efficacious approach for children under age six, particularly for behavioural challenges.
Resilience beyond insurance: coordination in crisis governance
Authors: Platzer Eva Katharina , Knodt Michèle 
Published: September 2023

AbstractThe latest report by the Intergovernmental Panel on Climate Change (IPCC) warns of an increase in heavy rainfall events due to global warming and climate change, which can result in significant economic costs for insurance companies and businesses. To address this challenge, insurance companies are focusing on developing new risk management strategies and offering new products such as flood insurance. However, the article argues that effective and feasible coordination shortens recovery time and can therefore drastically reduce the financial costs of a crisis—that is, the insurance costs. The paper analyses the deficit in crisis management during heavy rain events in Germany, based on the 2021 Ahr valley flood. The analysis is conducted based on document analysis and interviews and focuses on three areas of deficit: coordination between crisis staffs and (1) civil society, (2) emergency responders, and (3) political leaders. The paper highlights the importance of coordination during a crisis, which can help to address the crisis more efficiently and effectively, minimise damage and get communities back on their feet faster. The paper recommends policy changes to improve interface management and disaster management coordination.
The Idea That Digital Remote Learning Can Happen Anytime, Anywhere in Forced Online Teacher Education is a Myth
Authors: Šorgo Andrej , Ploj Virtič Mateja , Dolenc Kosta 
Published: September 2023

AbstractAn involuntary international experiment in which the entire student population was switched to digital remote learning due to the measures to stop COVID-19 put the paradigm of "anytime, anywhere learning" to the test. Online survey responses were obtained from 281 preservice primary and subject teachers. Using Structural Equation Modelling, connections were examined by inspection of path coefficients between constructs quality of personal digital technology, satisfaction, health, well-being, motivation, and physical activity. Problems with the quality of personal digital technology had a moderate influence on all constructs except motivation. Satisfaction influenced all constructs, well-being, and health the most. When comparing responses of the bottom and top third students based on the quality of personal digital technology, it was found that students who did not have the appropriate technology and workspace were less satisfied and suffered more. This is reflected in an increased incidence of problems related to health, well-being, and physical activity, along with a decrease in motivation. At least for the technologically deprived, the paradigm of "anytime, anywhere learning" is a myth. The study highlights the need for educational institutions to provide adequate technology and workspaces for all students in order to support their well-being and motivation during remote learning.
Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry
Authors: Rojas-Restrepo Jessica , Sindram Elena , Zenke Simon , Haberstroh Hanna , Mitsuiki Noriko , Gabrysch Annemarie , Huebscher Katrin , Posadas-Cantera Sara , Krausz Máté , Kobbe Robin , Rohr Jan C. , Grimbacher Bodo , Gámez-Díaz Laura 
Published: September 2023

AbstractVariants of uncertain significance (VUS) in CTLA4 are frequently identified in patients with antibody deficiency or immune dysregulation syndromes including, but not limited to, patients with multi-organ autoimmunity and autoinflammation. However, to ascertain the diagnosis of CTLA4 insufficiency, the functional relevance of each variant needs to be determined. Currently, various assays have been proposed to assess the functionality of CTLA4 VUS, including the analysis of transendocytosis, the biological function of CTLA4 to capture CD80 molecules from antigen presenting cells. Challenges of this assay include weak fluorescence intensity of the internalized ligand, poor reproducibility, and poor performance upon analyzing thawed cells. In addition, the distinction of pathogenic from non-pathogenic variants and from wild-type CTLA4, and the classification of the different VUS according to its level of CTLA4 dysfunction, would be desirable. We developed a novel CD80-expressing cell line for the evaluation of CD80-transendocytosis and compared it to the published transendocytosis assay. Our approach showed lower inter-assay variability and better robustness regardless the type of starting material (fresh or thawed peripheral mononuclear cells). In addition, receiver operating characteristic analysis showed 100% specificity, avoiding false positive results and allowing for a clear distinction between pathogenic and non-pathogenic variants in CTLA4-variant carriers. With our transendocytosis assay, we assessed the pathogenicity of 24 distinct CTLA4 variants from patients submitted to our diagnostic unit. Significantly impaired transendocytosis was demonstrated for 17 CTLA4 variants, whereas seven variants tested normal. In conclusion, our upgraded transendocytosis assay allows a reliable assessment of newly identified variants in CTLA4.
Topological Inference of the Conley Index
Authors: Yim Ka Man , Nanda Vidit 
Published: September 2023

AbstractThe Conley index of an isolated invariant set is a fundamental object in the study of dynamical systems. Here we consider smooth functions on closed submanifolds of Euclidean space and describe a framework for inferring the Conley index of any compact, connected isolated critical set of such a function with high confidence from a sufficiently large finite point sample. The main construction of this paper is a specific index pair which is local to the critical set in question. We establish that these index pairs have positive reach and hence admit a sampling theory for robust homology inference. This allows us to estimate the Conley index, and as a direct consequence, we are also able to estimate the Morse index of any critical point of a Morse function using finitely many local evaluations.
The stability and developmental interplay of word reading and spelling: a cross-linguistic longitudinal study from kindergarten to grade 4
Authors: Furnes Bjarte , Elwér Åsa , Samuelsson Stefan , Treiman Rebecca , Olson Richard K. 
Published: September 2023

AbstractWe investigated the stability and developmental interplay of word reading and spelling in samples of Swedish (N = 191) and U.S. children (N = 489) followed across four time points: end of kindergarten, grades 1, 2, and 4. Cross-lagged path models revealed that reading and spelling showed moderate to strong autoregressive effects, with reading being more predictable over time than spelling. Regarding the developmental interplay, we found a bidirectional relationship between reading and spelling from kindergarten to Grade 1. However, starting in Grade 1, reading predicted subsequent spelling beyond the autoregressor but not the other way around. In all analyses, the findings were similar across the two orthographies. The theoretical and practical implications of these findings are discussed.
Investigating the nexus between authentic leadership, employees’ green creativity, and psychological environment: evidence from emerging economy
Authors: Rehman Fazal Ur , Zeb Ali 
Published: September 2023

AbstractEmployees’ green creativity is the basic input to organizational innovation capabilities, the prime focus of practitioners to stay competitive, and a mean to solve the society’s sustainable issues in dynamic markets. Hence, this study aims to evaluate the nexus between authentic leadership, psychological environment, and employees’ green creativity based on the theoretical lenses of social identity and social exchange theories that have rare application in these domains. Data were collected through questionnaires from 367 operational staff members of different technical training centers of renewable energy projects in Rawalpindi and Islamabad regions at Pakistan. The findings reveal that authentic leadership is a significant precursor of employee’s green creativity and self-efficacy. In addition, self-efficacy mediates while the environment of trust and safety has non-mediating role in the relationship between authentic leadership and employee’s green creativity. This work brings attention to the initiatives in technical training centers for renewable energy projects and contributes to the field of employees’ green creativity in the context of authentic leadership and psychological environment based on the philosophy of social identity and social exchange theories.
Differential behavioral aging trajectories according to body size, expected lifespan, and head shape in dogs
Authors: Turcsán Borbála , Kubinyi Enikő 
Published: September 2023

AbstractThe twofold life expectancy difference between dog breeds predicts differential behavioral and cognitive aging patterns between short- and long-lived dogs. To investigate this prediction, we conducted a cross-sectional analysis using survey data from over 15,000 dogs. We examined the effect of expected lifespan and three related factors (body size, head shape, and purebred status) on the age trajectory of various behavioral characteristics and the prevalence of canine cognitive dysfunction (CCD). Our findings reveal that, although age-related decline in most behavioral characteristics began around 10.5 years of age, the proportion of dogs considered “old” by their owners began to increase uniformly around 6 years of age. From the investigated factors, only body size had a systematic, although not gradual, impact on the aging trajectories of all behavioral characteristics. Dogs weighing over 30 kg exhibited an earlier onset of decline by 2–3 years and a slower rate of decline compared to smaller dogs, probably as a byproduct of their faster age-related physical decline. Larger sized dogs also showed a lower prevalence of CCD risk in their oldest age group, whereas smaller-sized dogs, dolichocephalic breeds, and purebreds had a higher CCD risk prevalence. The identification of differential behavioral and cognitive aging trajectories across dog groups, and the observed associations between body size and the onset, rate, and degree of cognitive decline in dogs have significant translational implications for human aging research, providing valuable insights into the interplay between morphology, physiological ageing, and cognitive decline, and unravelling the trade-off between longevity and relative healthspan.