bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age and liver graft: a systematic review with meta-regression
Authors: Neri Ilaria , Pascale Marco Maria , Bianco Giuseppe , Frongillo Francesco , Agnes Salvatore , Giovinazzo Francesco 
Published: September 2023

AbstractIncreasing organ shortage results in extended criteria donors (ECD) being used to face the growing demand for liver grafts. The demographic change leads to greater use of elderly donors for liver transplantation, historically considered marginal donors. Age is still considered amongst ECD in liver transplantation as it could affect transplant outcomes. However, what is the cutoff for donor age is still unclear and debated. A search of PubMed, Scopus and Cochrane Library was performed. The primary outcome was 1-year graft survival (GS). The secondary outcome was overall biliary complications and 3–5 years of graft and overall survival. A meta-regression model was used to analyse the temporal trend relation in the survival outcome. The meta-analysis included 11 studies. Hazard ratios for 1-year (age cutoff of 70 and 80,) and 5-year GS (I2:0%) were similar irrespectively of the age group. The meta-regression analysis showed a significant correlation between the 1-year graft survival and the year of publication. (coef. 0.00027, 95% CI − 0.0001 to − 0.0003 p = 0.0009). Advanced-age donors showed an increased risk of overall biliary complications with an odd ratio (OR) of 1.89 (95% CI 1–3.65). Liver grafts potentially discharged because of high-risk failure show encouraging results, and GS in ECD has progressively improved with a temporal trend. Currently, the criteria of marginality vary amongst centres. Age alone cannot be considered amongst the extended criteria. First of all, because of the positive results in terms of septuagenarian graft survival. Moreover, the potential elderly donor-related adjunctive risk can be balanced by reducing other risk factors. A prospective multicentre study should investigate a multi-factorial model based on donor criteria, recipient features and new functional biomarkers to predict graft outcome, as proper donor–recipient matching seems to be the critical point for good outcomes.
Exercise in the Management of Metabolic-Associated Fatty Liver Disease (MAFLD) in Adults: A Position Statement from Exercise and Sport Science Australia
Authors: Keating Shelley E. , Sabag Angelo , Hallsworth Kate , Hickman Ingrid J. , Macdonald Graeme A. , Stine Jonathan G. , George Jacob , Johnson Nathan A. 
Published: September 2023

AbstractMetabolic-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease worldwide, affecting 25% of people globally and up to 80% of people with obesity. MAFLD is characterised by fat accumulation in the liver (hepatic steatosis) with varying degrees of inflammation and fibrosis. MAFLD is strongly linked with cardiometabolic disease and lifestyle-related cancers, in addition to heightened liver-related morbidity and mortality. This position statement examines evidence for exercise in the management of MAFLD and describes the role of the exercise professional in the context of the multi-disciplinary care team. The purpose of these guidelines is to equip the exercise professional with a broad understanding of the pathophysiological underpinnings of MAFLD, how it is diagnosed and managed in clinical practice, and to provide evidence- and consensus-based recommendations for exercise therapy in MAFLD management. The majority of research evidence indicates that 150–240 min per week of at least moderate-intensity aerobic exercise can reduce hepatic steatosis by ~ 2–4% (absolute reduction), but as little as 135 min/week has been shown to be effective. While emerging evidence shows that high-intensity interval training (HIIT) approaches may provide comparable benefit on hepatic steatosis, there does not appear to be an intensity-dependent benefit, as long as the recommended exercise volume is achieved. This dose of exercise is likely to also reduce central adiposity, increase cardiorespiratory fitness and improve cardiometabolic health, irrespective of weight loss. Resistance training should be considered in addition to, and not instead of, aerobic exercise targets. The information in this statement is relevant and appropriate for people living with the condition historically termed non-alcoholic fatty liver disease (NAFLD), regardless of terminology.
Effect of SIRT1 gene single-nucleotide polymorphisms on susceptibility to type 1 diabetes in a Han Chinese population
Authors: Li J. , Yang Y. , Xia Y. , Luo S. , Lin J. , Xiao Y. , Li X. , Huang G. , Yang L. , Xie Z. , Zhou Z. 
Published: September 2023

Abstract
Aims
SIRT1 deficiency has been associated with diabetes, and a variant of the SIRT1 gene has been found to be involved in human autoimmune diabetes; however, it is unclear whether this genetic variation exists in Han Chinese with type 1 diabetes (T1D) and whether it contributes to development of T1D. Therefore, we aimed to explore the association of the SIRT1 gene single-nucleotide polymorphisms (SNPs) rs10997866 and rs3818292 in a Han Chinese population with T1D.

Methods
This study recruited 2653 unrelated Han Chinese individuals, of whom 1289 had T1D and 1364 were healthy controls. Allelic and genotypic distributions of SIRT1 polymorphisms (rs10997866 and rs3818292) were determined by MassARRAY. Basic characteristics, genotype and allele frequencies of selected SNPs were compared between the T1D patients and healthy controls. Further genotype–phenotype association analysis of the SNPs was performed on the T1D patients divided into three groups according to genotype. Statistical analyses included the chi-square test, Mann‒Whitney U test, Kruskal‒Wallis H test and logistic regression.

Results
The allelic (G vs. A) and genotypic (GA vs. AA) distributions of SIRT1 rs10997866 were significantly different in T1D patients and healthy controls (P = 0.039, P = 0.027), and rs10997866 was associated with T1D susceptibility under dominant, overdominant and additive models (P = 0.026, P = 0.030 and P = 0.027, respectively). Moreover, genotype–phenotype association analysis showed the GG genotype of rs10997866 and the GG genotype of rs3818292 to be associated with higher titers of IA-2A (P = 0.013 and P = 0.038, respectively).

Conclusion
SIRT1 rs10997866 is significantly associated with T1D susceptibility, with the minor allele G conferring a higher risk of T1D. Moreover, SIRT1 gene rs10997866 and rs3818292 correlate with the titer of IA-2A in Han Chinese individuals with T1D.
A novel group decision-making approach based on partitioned Hamy mean operators in q-rung orthopair fuzzy context
Authors: Rawat Sukhwinder Singh , Komal  , Liu Peide , Stevic Zeljko , Senapati Tapan , Moslem Sarbast 
Published: September 2023

AbstractIn multi-attribute group decision-making (MAGDM), the attributes can be placed into independent groups based on their properties through partitioning. First, the partitioned dual Hamy mean (PDHM) operator is introduced, along with its essential properties. This operator integrates these separate groups while preserving the relationships between the attributes within each group. Furthermore, the partitioned Hamy mean (PHM) and the PDHM operators are also constructed in the generalized orthopair fuzzy environment, namely the q-rung orthopair fuzzy PHM (q-ROFPHM), the q-rung orthopair fuzzy PDHM (q-ROFPDHM), and their weighted forms. Their essential properties are verified to ensure the validity of the proposed aggregation operators (AOs). Subsequently, a new MAGDM approach is developed, employing the proposed AOs. The MAGDM problem of selecting the best person is examined. Moreover, the research includes a sensitivity analysis in three directions and a comparative analysis of the proposed MAGDM approach with five different approaches. The findings indicate that applying attribute partitioning in the proposed approach mitigates the adverse impact of irrelevant attributes, leading to more feasible and reliable outcomes. Additionally, a practical case study focuses on selecting a suitable industry for investment among the five available options. This case study demonstrates the approach’s effectiveness by considering five distinct qualities and results that make the Internet industry the best place to invest. Furthermore, a comparative analysis with four similar papers is also performed, indicating that the developed method’s results are more reliable and consistent.
Primary recognition, morality and AI
Authors: O’Hara Neil 
Published: September 2023

Abstract
This paper aims to show that the experience of ‘primary recognition’ (O’Hara in Moral certainty and the foundations of morality, Palgrave Macmillan, London, 2018) can be extended to human AI interactions. That is, I argue that human beings can (and do) experience non-rational, reflex moral responses to AI and social robots that fit O’Hara’s description of primary recognition. I give two plausible examples, one involving a military mine-sweeping robot and the other, a toy dinosaur called a ‘Pleo’. These experiences of primary recognition do not, however, settle the question of whether any particular AI can be considered a true moral patient or a ‘person’.
History of Avalanches in the Eastern Spanish Pyrenees
Authors: Blasco Mariño Robert , Martínez Iñigo Soteras , Bacardit Montserrat , Zafren Ken , Paal Peter 
Published: September 2023

Avalanches have caused injuries and deaths in mountain areas throughout history. We have examined the historical effects of avalanches on communities in the eastern Spanish Pyrenees. Surviving written records began in the year 1444 when an avalanche destroyed the village of Gessa. Many other avalanches since then have destroyed houses and other buildings and have caused injuries and deaths. In the 20th and 21st centuries, many villages evolved from agrarian areas to destinations for winter sports. The first known deaths during winter recreation likely occurred in 1930. Because of avalanche mitigation efforts, including relocating settlements, physical barriers, avalanche control measures, efforts to increase avalanche awareness, and avalanche warnings, avalanches now seldom affect inhabited areas in the eastern Spanish Pyrenees. Avalanche injuries and fatalities are now mainly limited to backcountry skiers and others traveling out of bounds near avalanche-controlled ski resorts.
Comparison of habitual physical activity in French Bulldogs, Pugs and normocephalic dogs by accelerometry
Authors: Aromaa Mimma , Putro Heikki , Lilja-Maula Liisa , Rajamäki Minna M 
Published: September 2023

AbstractBrachycephalic obstructive airway syndrome (BOAS) is a major welfare concern in flat-faced dog breeds. As BOAS causes respiratory difficulties and exercise intolerance, it can reduce dogs’ daily quality of life (QOL). However, evaluation of QOL in dogs is difficult, and many owners perceive BOAS signs as ‘normal’ for the breed. Accelerometers that measure frequency, duration and intensity of activities can offer an objective way of evaluating dogs’ daily activity and thereby deliver potential insights into QOL. The aim of this study was to assess habitual physical activity of 48 brachycephalic and 23 non-brachycephalic dogs using accelerometers. The accelerometers were used for one week and owners filled in a questionnaire regarding their dog’s well-being and activities. Veterinary-assessed BOAS grading for brachycephalic dogs was determined. Compared with controls, more severely affected French Bulldogs and Pugs had significantly lower total activity counts and spent less time in high activity. In Pugs, mildly affected dogs were also less active, but age can be a contributing factor here, as older age decreased activity in Pugs and controls showed a wider age range. In French Bulldogs, those dogs with no or mild signs of BOAS did not differ from controls regarding their daily activity. In conclusion, accelerometers were easy to use for objective measurement of daily activity in bracycephalic dogs, although a degree of discomfort due to the collar was reported. Results showed that BOAS signs were associated with decreased habitual physical activity. These findings emphasise the importance of actions taken to reduce incidence of BOAS in brachycephalic breeds.
How Surface-Level and Deep-Level Faultlines Influence Team Performance through Subgroup Formation and Team Interaction Quality: A Meta-analytic Review
Authors: Zhang Yue , Chen Hui 
Published: September 2023

AbstractThis article develops a framework to test how surface-level and deep-level faultlines impact team performance through subgroup formation and team interaction quality. We test it with 96 empirical articles on team faultlines from 2002 to 2022, using meta-analytic techniques. Firstly, results suggest that subgroup formation and team interaction quality act as serial mediums through which surface-level and deep-level faultlines exert negative indirect effects on team performance. Secondly, moderator analyses reveal that increasing interaction time will mitigate the effects of surface-level faultlines but enhance the effects of deep-level faultlines. Finally, surface- and deep-level social faultlines and deep-level task faultlines are detrimental to team interaction quality, and these negative effects are mediated by subgroup formation. Surface-level task faultlines are beneficial to team interaction, and this positive effect does not work through subgroup formation.
Replacing red and processed meat with lean or fatty fish and all-cause and cause-specific mortality in Norwegian women. The Norwegian Women and Cancer Study (NOWAC): a prospective cohort study
Authors: Enget Jensen Torill M. , Braaten Tonje , Jacobsen Bjarne Koster , Ibsen Daniel Borch , Skeie Guri 
Published: September 2023

AbstractNordic Nutrition Recommendations recommend reducing red and processed meat and increasing fish consumption, but the impact of this replacement on mortality is understudied. This study investigated the replacement of red and processed meat with fish in relation to mortality. Of 83 304 women in the Norwegian Women and Cancer Study (NOWAC) study, 9420 died during a median of 21·0 years of follow-up. The hazard ratios (HR) for mortality were estimated using Cox proportional hazards regression with analyses stratified on red and processed meat intake due to non-linearity. Higher processed meat (> 30 g/d), red and processed meat (> 50 g/d), and fatty fish consumption were associated with higher mortality, while red meat and lean fish consumption were neutral or beneficial. Among women with higher processed meat intake (> 30 g/d), replacing 20 g/d with lean fish was associated with lower all-cause (HR 0·92, 95 % CI 0·89, 0·96), cancer (HR 0·92, 95 % CI 0·88, 0·97) and CVD mortality (HR 0·82, 95 % CI 0·74, 0·90), while replacing with fatty fish was associated with lower CVD mortality (HR 0·87, 95 % CI 0·77, 0·97), but not with all-cause or cancer mortality. Replacing processed meat with fish among women with lower processed meat intake (≤ 30 g/d) or replacing red meat with fish was not associated with mortality. Replacing processed meat with lean or fatty fish may lower the risk of premature deaths in Norwegian women, but only in women with high intake of processed meat. These findings suggest that interventions to reduce processed meat intake should target high consumers.
Public services and the urban middling sort: the provision of water in Bristol, Chester and Ipswich, 1540–1640
Authors: Winter Mabel 
Published: September 2023

AbstractThis article examines the relationship between public services and the urban middling sort in provincial England from 1550 to 1640 through comparative case-studies of the finance and management of waterworks, the creation of new skilled roles and the cultural import of water systems in Bristol, Chester and Ipswich. It argues that the middling sort were vital in establishing public services and that water provision centred not only on its value as a material and financial resource, but also as an expanding source of patronage and social capital that shaped and entrenched the emergence of middling groups in society.
Automatic enrollment with a 12 percent default contribution rate
Authors: Beshears John , Guo Ruofei , Laibson David , Madrian Brigitte C. , Choi James J. 
Published: September 2023

AbstractWe study a retirement savings plan with a default contribution rate of 12 percent of income, which is much higher than previously studied defaults. Twenty-five percent of employees had not opted out of this default 12 months after hire; a literature review finds that the corresponding fraction in plans with lower defaults is approximately one-half. Because only contributions above 12 percent were matched by the employer, 12 percent was likely to be a suboptimal contribution rate for employees. Employees who remained at the 12 percent default contribution rate had average income that was approximately one-third lower than would be predicted from the relationship between salaries and contribution rates among employees who were not at 12 percent. Defaults may influence low-income employees more strongly in part because these employees face higher psychological barriers to active decision making.
Temporal Variations in Vertical Cloud Structure of Jupiter's Great Red Spot, Its Surroundings and Oval BA From HST/WFC3 Imaging
Authors: Anguiano‐Arteaga Asier , Pérez‐Hoyos Santiago , Sánchez‐Lavega Agustín , Sanz‐Requena José Francisco , Irwin Patrick G. J. 
Published: September 2023

AbstractIn this study, we present the evolution of the properties and vertical distribution of the hazes in Jupiter's Great Red Spot (GRS), its surroundings and Oval BA from 2015 to 2021. To retrieve the main atmospheric parameters, we model the spectral reflectivity of a number of dynamically and/or spectrally interesting regions with a radiative transfer tool that uses an optimal estimator scheme. The spectra of the selected regions are obtained from high‐resolution Hubble Space Telescope Wide Field Camera 3 images that cover the spectral range from 200 to 900 nm. The a priori model atmosphere used to describe the various Jovian regions is taken from Anguiano‐Arteaga et al. (2021, https://doi.org/10.1029/2021JE006996) for each corresponding area. We find that the biggest variations in the GRS occur in the optical thickness of the stratospheric and tropospheric haze layers starting in 2019 and in the mean size of the tropospheric haze particles in 2018. The absorption spectra of both hazes show little variations among the analyzed regions and years, with the stratospheric haze properties seeming compatible with the chromophore proposed by Carlson et al. (2016, https://doi.org/10.1016/j.icarus.2016.03.008). We report a color change of Oval BA from red to white during these years that, according to our models, can be mostly explained in terms of a decrease in the stratospheric haze optical depth.
Changes in Dissolved Inorganic Carbon Across Yangtze River Regulated by Dam and River‐Lake Exchange
Authors: Zhao Chu , Wang Chuan , Li Jianhong , Meng Lize , Xue Jingya , Gao Yang , Huang Tao , Bai Yixin , Li Shuaidong , Yang Hao , Shi Kun , Xu Yuanhui , Huang Changchun 
Published: September 2023

AbstractThe boom in dam construction and continuous river‐lake exchange has had a profound impact on the transmission and transformation of riverine dissolved inorganic carbon (DIC). An in‐depth understanding of the change mechanisms of DIC concentrations and sources driven by dam operation and lake recharge is crucial for regulating greenhouse gas emissions and evaluating the impact of DIC on the global carbon cycle. This study investigated dam‐ and lakes‐driven DIC via the concentration and δ13C of DIC, combined with anions, cations, δD and δ18O in the main stream of the Yangtze River. DIC showed a decreasing trend from upper reach (2,262.31 ± 113.69 μmol kg−1) to lower reach (1,771.61 ± 89.36 μmol kg−1). Carbonate dissolution proportion (from 36.45% to 28.44%) and atmospheric CO2 proportion (from 37.51% to 22.94%) of DIC decreased from upper reach to lower reach, whereas soil CO2 proportion of DIC (from 26.01% to 48.63%) increased. The control of dam operation on DIC biogeochemical process was revealed from different time scales. From the perspective of short‐term seasonal changes (from 2020 to 2021), the mineralization of organic matter in the dry season strengthened CO2 degassing and calcite precipitation, reducing the DIC and increasing the proportion of soil CO2. Meanwhile, longer periods of runoff retention provided sufficient time for water–rock reactions in the wet season and increased the DIC and carbonate dissolution source in the reservoir area. On a long‐term scale (from 2009 to 2021), a decrease in pH driven by sediment mineralization contributed to an annual increase in DIC in the reservoir. The flow of lakes mixed into the mainstream was revealed by the enrichment of δ18O, and river‐communicating recharge decreased the DIC and carbonate dissolution source. We show that dam operation and lake inflow change DIC concentrations and sources and therefore need to be considered in the transmission and transformation processes of DIC in the river‐ocean continuum.
Influence of the Thermal Structure on the Intensification of the Extreme Arctic Cyclone in August 2016
Authors: Qian Qian , Zhong Wei , Yao Yao , Zhang Deyuan 
Published: September 2023

AbstractAs one of the most dangerous weather systems affecting the Arctic region, Arctic cyclones (ACs) significantly affect Arctic shipping routes and navigation safety. This study investigates the evolution and structure characteristics of an extreme AC in August 2016 (AC16) based on the Arctic System Reanalysis version 2 (ASRv2) data set. The key factors affecting the development of AC16 are revealed by diagnosing the pressure tendency equation (PTE), with focus on the influence of thermal structure during two rapid intensification stages. It is found that PTE‐diagnosed results can well reproduce the evolution of AC16. The air‐column virtual temperature change is the decisive contributor decreasing the surface pressure and thus intensifying AC16, while the change in geopotential at upper boundary and the mass change caused by evaporation and precipitation have less effect. Further analysis indicates that at the initial rapid intensification stage, the middle‐lower‐level diabatic heating probably related to condensation latent heat and the upper‐level warm advection influenced by tropopause polar vortices (TPVs) have crucial effects on the air‐column warming, which leads to the AC16 rapid intensification initially. At the secondary rapid intensification stage, the upper‐level warm advection affected by TPVs further increases the air‐column virtual temperature, which is the dominant contributor to the AC16 secondary drastic intensification.