bluuebunny/crossref_metadata_2025_split huggingface dataset:
TRAV26-2 T-Cell Receptor Expression Is Associated With Mucosal Lymphocyte Response to Wheat Proteins in Patients With Functional Dyspepsia
Authors: Burns Grace L. , Potter Michael , Mathe Andrea , Bruce Jessica , Minahan Kyra , Barnes Jessica L. , Pryor Jennifer , Nieva Cheenie , Sherwin Simonne , Cuskelly Annalisa , Fairlie Thomas , Cameron Raquel , Bollipo Steven , Irani Mudar Zand , Foster Robert , Gan Lay T. , Shah Ayesha , Koloski Natasha , Foster Paul S. , Horvat Jay C. , Walker Marjorie M. , Powell Nick , Veysey Martin , Duncanson Kerith , Holtmann Gerald , Talley Nicholas J. , Keely Simon 
Published: September 2023

INTRODUCTION:
An association between functional dyspepsia (FD) and wheat-containing foods has been reported in observational studies; however, an adaptive response has not been demonstrated. We examined whether antigens present in wheat could provoke a response from FD duodenal lymphocytes.

METHODS:
Lamina propria mononuclear cells (LPMCs) were isolated from duodenal biopsies from 50 patients with FD and 23 controls. LPMCs were exposed to gluten (0.2 mg/mL) or gliadin (0.2 mg/mL) for 24 hours. Flow cytometry was performed to phenotype lymphocytes. Quantitative PCR was used to measure the expression of gliadin-associated T-cell receptor alpha variant (TRAV)26-2.

RESULTS:
In response to gliadin (but not gluten) stimulation, the effector Th2-like population was increased in FD LPMCs compared with that in controls and unstimulated FD LPMCs. Duodenal gene expression of TRAV26-2 was decreased in patients with FD compared with that in controls. We identified a positive association between gene expression of this T-cell receptor variant and LPMC effector Th17-like cell populations in patients with FD, but not controls after exposure to gluten, but not gliadin.

DISCUSSION:
Our findings suggest that gliadin exposure provokes a duodenal effector Th2-like response in patients with FD, supporting the notion that food antigens drive responses in some patients. Furthermore, these findings suggest that altered lymphocyte responses to wheat proteins play a role in FD pathogenesis.
Investigating pyrolysis characteristics of Shengdong coal through Py-GC/MS
Authors: Su Xiaoping , Wang Xiangtong , Li Ning , Shen Tao , Zhang Ping , Sun Ming , Ma Xiaoxun 
Published: September 2023

Abstract
Shengdong coal was single-step and multi-step pyrolyzed by pyrolysis-gas chromatography/mass spectrometry. In the single-step pyrolysis process, Mono-ring aromatics contents reach a maximum value at 800°C, while phenolic contents are significantly reduced, which might be attributed to the dehydroxylation of phenolics. Naphthalene content also reaches a maximum value at 800°C in the single-step pyrolysis process; however, naphthalene was not detected in the multi-step pyrolysis process. So naphthalene might come from the ring-opening of multi-ring aromatics or the cyclization of mono-ring aromatics in the single-step pyrolysis process. Only phenol and o-cresol were detected, but no p-cresol in the multi-step pyrolysis process; however, p-cresol content reaches a maximum value at 800°C, meanwhile, phenol content was decreased and o-cresol was disappeared in the single-step pyrolysis process, which suggests that p-cresol may be derived from isomerization of o-cresol or alkylation of phenol. It provides an idea for strengthening more basic research related to the rapid pyrolysis of coal.
On the quadratic residues and their distribution properties
Authors: Liu Xiaoge , Meng Yuanyuan 
Published: September 2023

Abstract
The main purpose of this article is to use elementary methods and properties of classical Gauss sums to determine identities for the number of residue systems of

a

a

mod

p

p

such that

a

a

,

a
+

a

¯

a+\bar{a}

, and

a
−

a

¯

a-\bar{a}

are all quadratic residues, improving on results of Wang and Lv.
Research on absolute ranging technology of resampling phase comparison method based on FMCW
Authors: Sun Bin , Song Junfang , Wang Chao , Li Lanlan , Tan Linqiu 
Published: September 2023

Abstract
As an advanced optical precision ranging method, FMCW (frequency-modulated continuous-wave) laser interferometric ranging technology can achieve a large-scale and high-precision absolute distance measurement, so it has high research and application value in the field of coordinate measurement in large space. How to improve the resolution and stability of laser interferometry is a research difficulty in this technology. Based on FMCW laser interferometry relative distance technology, a method for achieving absolute distance measurement through phase comparison after repeated sampling is proposed. Using the FMCW laser distance measuring system, two interference optical paths of measuring interferometer and auxiliary interferometer are constructed, respectively. Synchronous sampling is performed on two interference signals, and the phase ratio of the two interference signals is obtained through the extracted frequency information. The optical path difference of the unknown measurement interferometer is derived from the known auxiliary interferometer information. This method uses a triangular wave modulation laser to reduce the influence of Doppler frequency shift and eliminate quantization errors. By using the fixed-point repeated sampling, the optical path difference information is quickly extracted, and the nonlinear error of laser interference frequency modulation is effectively reduced.
Wetting behaviour of ionic surfactants on the aluminium foil
Authors: Rai Summi , Rauniyar Bishnu Shau , Bhattarai Ajaya 
Published: September 2023

Abstract
Aluminium foil is a versatile material used in various industries, but its inherent low wettability limits its application. Surfactant can be used as effective agents for enhancing the wettability, enabling improved surface interactions and performance. In this study, we investigated the wettability of anionic (SDS and AOT) and cationic (CTAB) surfactants prepared in water as well as in isopropanol-water solvents with the four different volume fractions (0.1, 0.2, 0.3 and 0.4) on aluminium foil surfaces by measuring the contact angle. As the volume fraction of isopropanol on aluminium foil increases, the contact angle of SDS, CTAB, and AOT increases whereas the surface free energy decreases, indicating the hydrophobic nature of the surface. This trend is observed with the increasing concentrations of various solvents used. The adhesion work exhibits a linear increase with alcohol surface tension. A curvilinear variation is observed in the plots between cos

θ

$\theta $

and 1/

γ
SL

$\sqrt{{\gamma }_{\text{SL}}}$

. The plots of adhesion work versus contact angles show non-linear variation. Additionally, the plot of cos

θ

$\theta $

against the surface tension of alcohol and adhesion work against log C exhibit curvilinear variation. With these results, the article aims to provide valuable insights into the application of surfactants for improving the wettability of aluminium foil.
Characterization of Born Carbide and Rice Husk Ash Reinforced Aluminum Alloy Composites
Authors: Muralimohan R. , Kempaiah U. N. , Veeresh Kumar G. B. 
Published: September 2023

Abstract
The remarkable characteristics of aluminum alloys, like their hardness, strength-to-weight ratio, fatigue, corrosion resistance, play a decisive role in the aeronautical and automotive industries. However, scientists are on the lookout for substantial advancements in the wear resistance of the composites under varied service situations. This investigation focuses on the characteristics of hybrid metal matrix composites with regards to optical, physical, mechanical, tribological, and corrosion behavior of ADC12 alloy reinforced by born carbide and rice husk ash (RHA) particulates. The liquid metallurgy process with the stir casting technique was used to produce the hybrid composites, which were then compared to monolithic materials. In the fabrication, reinforcement RHA was added from 0 to 12 % while maintaining a born carbide content of 5 %. Following ASTM standards, the resulting composites were put through optical, several physical, mechanical, wear, and corrosion testing. The experimental findings were then analyzed. With a rise in the amount of reinforcement in the base alloy, physical and mechanical characteristics greatly improved, whereas the percentage of elongation was seen to decline. The effects of exposure time were studied on the hybrid composites on corrosion behavior in acidic environments. The composites are exposed to the hydrochloric acid solution, and weight loss over various periods, from 12 to 72 h, is measured in steps of 12 h. It was discovered that the corrosion resistance increased as the reinforcing content increased. By using a pin-on-disc apparatus, the wear tests were conducted, and the outcomes indicated the composites’ superior wear resistance. Composites with a higher percentage of reinforcement displayed superior characteristics. Following the tensile testing, broken surfaces, wear, and corrosion morphology are examined in scanning electron microscope images. The research findings are thoroughly examined, and careful interpretations have been made.
The Arousal-Related “Central Thalamus” Stimulation Site Simultaneously Innervates Multiple High-Level Frontal and Parietal Areas
Authors: Morais Paulo L. A. G. , Rubio-Garrido Pablo , de Lima Ruthnaldo M. , Córdoba-Claros Angélica , de Nascimento Expedito S. , Cavalcante Jeferson S. , Clascá Francisco 
Published: September 2023

In human and nonhuman primates, deep brain stimulation applied at or near the internal medullary lamina of the thalamus [a region referred to as “central thalamus,” (CT)], but not at nearby thalamic sites, elicits major changes in the level of consciousness, even in some minimally conscious brain-damaged patients. The mechanisms behind these effects remain mysterious, as the connections of CT had not been specifically mapped in primates. In marmoset monkeys (Callithrix jacchus) of both sexes, we labeled the axons originating from each of the various CT neuronal populations and analyzed their arborization patterns in the cerebral cortex and striatum. We report that, together, these CT populations innervate an array of high-level frontal, posterior parietal, and cingulate cortical areas. Some populations simultaneously target the frontal, parietal, and cingulate cortices, while others predominantly target the dorsal striatum. Our data indicate that CT stimulation can simultaneously engage a heterogeneous set of projection systems that, together, target the key nodes of the attention, executive control, and working-memory networks of the brain. Increased functional connectivity in these networks has been previously described as a signature of consciousness.SIGNIFICANCE STATEMENTIn human and nonhuman primates, deep brain stimulation at a specific site near the internal medullary lamina of the thalamus [“central thalamus,” (CT)] had been shown to restore arousal and awareness in anesthetized animals, as well as in some brain-damaged patients. The mechanisms behind these effects remain mysterious, as CT connections remain poorly defined in primates. In marmoset monkeys, we mapped with sensitive axon-labeling methods the pathways originated from CT. Our data indicate that stimulation applied in CT can simultaneously engage a heterogeneous set of projection systems that, together, target several key nodes of the attention, executive control, and working-memory networks of the brain. Increased functional connectivity in these networks has been previously described as a signature of consciousness.
Evaluación de un anuncio digital para un nuevo producto de cosmética natural
Authors: Salgado-Beltran Lizbeth , Mendoza Canales Juan Ramón 
Published: September 2023

La comunicación es elemento clave en las acciones del marketing. Comprender cómo los consumidores interactúan emocionalmente por el canal para decidir la compra es esencial para el diseño de las estrategias de la organización. Esta investigación tiene como finalidad valorar la reacción emocional de un anuncio digital para un nuevo producto dermofarmacéutico. El estudio de enfoque mixto se realizó en cuatro fases: i) producto seleccionado, ii) técnicas aplicadas (focus groups, encuesta y diseño del anuncio digital), iii) elaboración del instrumento y iv) análisis de datos (conteo de palabras, descriptivo y factorial). Como resultado hay inclinación de sentimientos positivos por parte de los participantes; provoca confianza, encanto, y las hace sentir atractivas. Los sentimientos negativos se encuentran en un término intermedio como ambiguo, debido posiblemente al origen natural del artículo, y los sentimientos de relajado se inclinan al factor cálido. Esto evidencia que las respuestas que llegan a la mente del individuo al estar expuesto a un estímulo no solo son cognitivas, sino también emocionales. Los principales resultados muestran que la utilización de formatos emocionales por parte de las organizaciones puede ser de utilidad al integrar el mensaje del producto con distintas actividades. Como limitaciones, se establece la baja cuota de respuesta en las redes sociales.
“You are always left with doubts”: information access among HPV-positive women in Greater Buenos Aires
Authors: Szwarc Lucila , Sánchez Antelo Victoria , Paolino Melisa , Arrossi Silvina 
Published: September 2023

Objetivos Las mujeres con resultado positivo de test de Virus de Papiloma Humano (VPH) y resultados negativo o normal de Papanicolau (VPH+/Pap-) presentan un riesgo alto de desarrollar lesiones en el cuello del útero, pero tienen muy bajos niveles de adherencia al seguimiento en Argentina. Este estudio se propuso identificar las necesidades de información, las fuentes de información y las barreras de acceso a la información de mujeres con VPH positivo y Pap normal o negativo luego de haber recibido los resultados del tamizaje.
Métodos Con una estrategia de investigación cualitativa, se realizaron 22 entrevistas virtuales semiestructuradas a mujeres con VPH positivo y Papanicolaou normal o negativo (VPH+/Pap-). Las mujeres elegibles tenían entre 30 y 64 años y residían en un área suburbana de Buenos Aires. Los datos de las entrevistas fueron analizados temáticamente utilizando los módulos de la guía de entrevistas. Se codificaron las categorías emergentes como subtemas, lo cual posibilitó un análisis temático.

Resultados Existen necesidades de información percibidas entre las mujeres con VPH positivo y Papanicolaou normal o negativo. Estas necesidades incluyen información sobre: la transmisión sexual del virus (desmontando la asociación con la infidelidad y considerando la posibilidad de transmisión no sexual), el significado del diagnóstico y su relación con el cáncer, asícomo el seguimiento y la ausencia de tratamiento. Por otro lado, existen necesidades de información no percibidas, como la asociación entre el resultado y otros problemas de salud ginecológicos, y las ideas erróneas socioculturales sobre el VPH. Las fuentes de información comunes para estas mujeres son la visita médica, la consulta en internet y el diálogo con los familiares. Sin embargo, existen barreras que dificultan el acceso a la información, como la información inexacta en internet, la falta de información proporcionada por los profesionales y las dificultades para hacer preguntas durante la consulta médica.
Conclusiones Es fundamental reforzar los procesos de entrega de resultados y considerar nuevos formatos para proporcionar información a las mujeres VPH+, tanto con Pap normal como anormal.
Meal Provision in Schools and in the Street. The Historical Roots of School Catering in Budapest
Authors: Umbrai Laura 
Published: September 2023

AbstractThe introduction of school meals in the 20th century has its roots in several parallel but independent initiatives. The common source of these initiatives was the practice of philanthropy and charity, based on religious upbringing. Public catering for children was first institutionalized in Budapest by a charitable organization, the Children's Society (Gyermekbarátok Egyesülete), after which several denominational associations followed suit. In the early 20th century, the City of Budapest itself also took the initiative, setting up its first daycare centers where needy children were not only fed but also participated in educational and recreational activities. Resources for social welfare were eroded during the war, thus foreign aid organizations stepped in to help the children of Budapest immediately after the war, while childcare became the sole responsibility of the public authorities from the 1920s. From then on, the state covered the entire costs of providing meals, similar to the system of soup kitchens established specifically for supplying food to destitute adults.
Antibiotic-related adverse events and risk factors in hospitalized patients: a prospective cohort study
Authors: SOYSAL Orcun , ŞENCAN İrfan , KORKMAZ Nesibe 
Published: September 2023

Purpose: The objective of this study is to identify antibiotic-related adverse events and risk factors in hospitalized patients.
Materials and Methods: This prospective cohort study included 776 inpatients who received antibiotic treatment between January 2019 and December 2020. Patients who experienced "definite" or "probable" adverse drug events (ADE) were examined using the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria. The definition and severity criteria for antibiotic-related adverse events were determined according to the Common Terminology Criteria for Adverse Events (CTCAE).
Results: The overall rate of antibiotic-associated ADE was 7.9 (95%CI, 6.8-9.1) per 1000 person-days. The study identified a total of 152 adverse events in 125 patients who experienced ADE. Among the 152 adverse events, 63 (41.4%) were severe, and 89 (58.6%) were non-severe. Independent risk factors for ADE included the number of comorbidities (up to 4 times higher increased risk), number of drugs used, and duration of antibiotic administration (up to 12.3 times higher and 8% increased risk for each additional day). The most common side effects were hematological, with 45 (29.6%) cases reported in the hematological system advers events.
Conclusion: The management of antibiotic durations, which is a controllable factor in the development of antibiotic-related adverse events, is crucial. Rational use of antibiotics is essential, not only in terms of preventing the development of resistance but also in terms of reducing the frequency of adverse events that may become life-threatening.
The protective effect of tangeretin and pomegranate separately and in combination on ethanol-induced acute gastric ulcer model
Authors: SUSAM Solmaz , İLHAN Nevin , TEDİK Fatma , BERK Buket , İLHAN Ayşe Şebnem 
Published: September 2023

Purpose: This study was designed to find an answer to the question, "Is it beneficial to use pomegranate (POM) and tangeretin (TAN) separately or in combination, for the prevention of acute gastric ulcer?".
Materials and Methods: The gastroprotective effect of tangeretin and pomegranate was determined by measuring the levels of the selected inflammatory cytokines [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1β and IL-10], lipid peroxides, and enzymatic activities of antioxidants in gastric tissue samples.
Results: When all groups are written as control, gastric ulcer, POM+EtOH, TAN+EtOH and POM+TAN+EtOH, respectively; IL-1β cytokine levels were measured as 0.147, 0.24, 0.228, 0.195 and 0.182 pg/g protein. IL-6 levels; 16,857, 25,923, 19,797, 18,838 and 17,896 pg/mg protein. TNF-α levels were 39,916, 49.97, 44,678, 41,673 and 40,844 pg/mg protein. Finally, IL-10 levels were measured as 33,496, 28,071, 29,693, 30,073 and 30,008 pg/mg protein. SOD activities were determined as 18,038, 13,731, 15,506, 14,439, and 15,943. CAT activities were 674,638, 639,964, 673,382, 664,691, and 671,203. Protein carbonyl levels were measured as 26,799, 40,30, 33,052, 34,579 and 32,79. Finally, MDA levels were found as 5,239, 9,814, 6,695, 5,771 and 5,836. Briefly, POM and TAN showed their antioxidant functions by decreasing the levels of malondialdehyde (MDA), and protein carbonyl and increasing the activity of superoxide dismutase (SOD) and catalase (CAT). And also, these protective agents exhibited their anti-inflammatory functions by decreasing the content of TNF-α, IL-6, and IL-1β, and increasing the IL-10 levels.
Conclusion: Tangeretin and pomegrenate have a potential gastroprotective effect against ethanol-induced acute gastric ulcer and that the combined treatment is more beneficial than the effect of POM or TAN alone. In addition, this effect is thought to be due to the fact that both selected flavonoids can show a synergistic effect, reducing the levels of inflammation parameters and increasing antioxidant levels.
Comparison of the prevalence of sexual dysfunction in panic disorder patients in terms of gender
Authors: TÜNEL Munever 
Published: September 2023

Purpose: The aim of this study is to evaluate the frequency of sexual dysfunction in male and female panic disorder (PD) patients and to make a comparison between genders.
Materials and Methods: A total of 57 cases, including 33 females aged 36±6 years and 24 males aged 35±7 years, who were sexually active, did not use psychotropic drugs, with primary diagnosis of PD according to DSM-5, were included in the study. Individual information collection forms and the Arizona Sexual Experiences Scale (ASEX) were applied to all cases, and sexual dysfunctions (SD) were questioned.
Results: According to the suggested cut-off score of the Turkish version of the Arizona Sexual Experiences Scale, 77.2% of all participants had SD. SD was detected in 81.8% of women and 70.8% of men. There was a significant difference between men and women in terms of ASEX total scores. There was no significant difference between men and women in terms of sexual desire and orgasm satisfaction. Sub-dimension scores of arousal, lubrication/erection, and reaching orgasm were significantly higher in females. Sexual reluctance was the most common in both genders, with 30.4% of women and 36.5% of men.
Conclusion: Sexual dysfunction is common among PD patients. Sexual reluctance is the most common in male and female patients with PD. Arousal and orgasm problems are more common in female PD patients than in male PD patients.