bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personal infection prevention behaviors and campaign to encourage travel during COVID-19: A cross-sectional study
Authors: Shimoda Hayato , Nagata Tomohisa , Ishimaru Tomohiro , Hino Ayako , Ando Hajime , Muramatsu Keiji , Tateishi Seiichiro , Tsuji Mayumi , Mori Koji 
Published: February 2023

IntroductionThe Go To Travel campaign in Japan was launched to subsidize travel and accommodation costs for tourists through vouchers that could be used at domestic destinations. Infection prevention behavior can lead to refraining from travel owing to infection concerns; conversely, taking preventive action can promote travel. There is a lack of information about the association between infection prevention behaviors and desire to travel. During a pandemic of infection, there is the difficult challenge of balancing the promotion of infection prevention behavior with economic revitalization. Thus, we examined the relationship between personal infection prevention behaviors and using Go To Travel.MethodsWe conducted a cross-sectional study of 26,637 workers who responded to a large-scale questionnaire survey about COVID-19 in Japan. We built multilevel logistic regression models adjusted for confounders to assess the association between each personal infection prevention behavior and using Go To Travel. We analyzed the seven infection prevention behavior individually: wearing a mask when among other people; disinfecting hands with alcohol before going indoors; washing hands after using the toilet; gargling upon returning home; opening a window to ventilate a room; carrying an alcohol sanitizer; and disinfecting hands after touching objects outside.ResultsAmong the 26,637 participants, 7,959 (30%) used Go To Travel. For “wearing a mask in the presence of others” and “washing hands after using the toilet,” the majority of respondents answered “almost always: 86.5 and 85.6% respectively. Action “carrying alcohol disinfectant” was the least implemented, with 36.9% of respondents saying “almost never.” Two of the seven preventive behaviors (“disinfecting hands with alcohol before going indoors” and “carrying alcohol disinfectant”) were positively related to using Go To Travel, that is, the more of these actions they took, the more they used Go To Travel (p for trend &lt;0.001).ConclusionsTo balance pandemic preparedness with economic preparedness, it is also necessary to promote travel when the infection situation is calm. However, since human mobility can be a factor that exacerbates the infection situation, it is necessary to promote more infection prevention behaviors among individuals. We confirmed that Go To Travel users were basically doing a good infection prevention behaviors, but they tended not to wash their hands after touching things or carry alcohol sanitizer. It is necessary to encourage these measures to be taken when traveling.
Prevalence and associated factors of cross-sectional and incident self-reported arthritis or rheumatism among a national community sample of middle-aged and older adults in Thailand
Authors: Pengpid Supa , Peltzer Karl 
Published: February 2023

BackgroundThe study aimed to assess the prevalence and associated factors of cross-sectional and incident arthritis or rheumatism among a national community sample of middle-aged and older adults in Thailand.MethodsWe analyzed cross-sectional and longitudinal data from two consecutive waves (2015 and 2017) of the Health, Aging, and Retirement in Thailand (HART) study. Arthritis or rheumatism (SRA) was assessed by self-reported health care provider diagnosis.ResultsThe cross-sectional (baseline) sample included 5,616 participants (≥45 years, median age 66 years, interquartile range 57 to 76 years) and the incident (follow-up) sample included 3,545 participants. The prevalence of SRA in the cross-sectional sample (baseline) was 4.0% and in the incident (follow-up) sample 5.3%. In the cross-sectional multivariable model, obesity class I (aOR: 1.78, 95% CI: 1.19 to 2.67), obesity class II (aOR: 1.82, 95% CI: 1.02 to 3.25), hypertension (aOR: 1.90, 95% CI: 1.35 to 2.66), brain disease and/or psychiatric problems (aOR: 4.79, 95% CI: 2.27 to 10.62), sleep problem (aOR: 1.45, 95% CI: 1.01 to 2.07) and prescription drug use (aOR: 1.63, 95% CI: 1.14 to 2.33) were positively associated, and not in the labor force (aOR: 0.53, 95% CI: 0.34 to 0.84), and employed (aOR: 0.63, 95% CI: 0.41 to 0.99) were negatively associated with SRA. In the incident multivariable model, obesity class I (aOR: 1.78, 95% CI: 1.17 to 3.61), obesity class II (aOR: 2.01, 95% CI: 1.12 to 3.61), poor mental health (aOR: 1.69, 95% CI: 1.19 to 2.41), and functional disability (aOR: 2.04, 95% CI: 1.01 to 4.13) were positively associated, and current alcohol use (aOR: 0.50, 95% CI: 0.25 to 0.99) was negatively associated with SRA.ConclusionThe middle and older Thai adults had a low prevalence and incidence of SRA, and several physical and mental risk factors for cross-sectional and/or incident SRA were identified.
Do changes in working hours increase stress in Japanese white-collar workers?
Authors: Ozawa Masaki , Anzai Tatsuhiko , Yamauchi Takashi , Takahashi Kunihiko 
Published: February 2023

IntroductionHigh stress at work is associated with negative health outcomes for workers, making stress prevention a critical challenge. Overtime work is an influential stress factor. This study, therefore, aimed to longitudinally evaluate how stress increased depending on changes in working hours among Japanese white-collar workers.MethodsWe targeted 3,874 participants who were full-time workers and were recognized as having low stress in a web-based cohort in 2018 (T1) and 2019 (T2). We performed univariate and multivariate logistic regression with the following variables: years of experience, years of education, medical background, income, and roommates.ResultsWe observed a greater increase in stress among female who worked 41–50 h per week at T1 and more than 50 hours per week at T2, and those who worked more than 50 h per week at T1 and 35–40/41–50 h per week at T2, compared to those who worked 41–50 h per week both at T1 and T2, with odds ratios (ORs) and 95% confidence intervals (95% CI) of OR = 2.09, 95% CI (1.18, 3,70); OR =1.86, 95% CI (1.14, 3.03), respectively. However, no association between change in working hours and stress was found among male.DiscussionThese results show that reducing stress requires decreasing working hours as well as identifying factors that lead to high stress.
Association between composite lifestyle factors and cardiometabolic multimorbidity in Chongqing, China: A cross-sectional exploratory study in people over 45 years and older
Authors: Zheng Yuanjie , Zhou Zhongqing , Wu Tingting , Zhong Kailuo , Hu Hailing , Zhang Hengrui , Sun Rong , Liu Weiwei 
Published: February 2023

IntroductionModifiable lifestyle factors are considered key to the control of cardiometabolic diseases. This study aimed to explore the association between multiple lifestyle factors and cardiometabolic multimorbidity.MethodsA total of 14,968 participants were included in this cross-sectional exploratory study (mean age 54.33 years, range 45–91; 49.6% male). Pearson's Chi-square test, logistic regression, and latent class analysis were employed.ResultsWe found that men with 4–5 high-risk lifestyle factors had a 2.54-fold higher risk (95% CI: 1.60–4.04) of developing multimorbidity compared to males with zero high-risk lifestyle factors. In an analysis of dietary behavior, we found that in women compared to men, over-eating (OR = 1.94, P &lt; 0.001) and intra-meal water drinking (OR = 2.15, P &lt; 0.001) were more likely to contribute to the development of cardiometabolic multimorbidity. In an analysis of taste preferences, men may be more sensitive to the effect of taste preferences and cardiometabolic multimorbidity risk, particularly for smoky (OR = 1.71, P &lt; 0.001), hot (OR = 1.62, P &lt; 0.001), and spicy (OR = 1.38, P &lt; 0.001) tastes. Furthermore, “smoking and physical activity” and “physical activity and alcohol consumption” were men's most common high-risk lifestyle patterns. “Physical activity and dietary intake” were women's most common high-risk lifestyle patterns. A total of four common high-risk dietary behavior patterns were found in both males and females.ConclusionsThis research reveals that the likelihood of cardiometabolic multimorbidity increases as high-risk lifestyle factors accumulate. Taste preferences and unhealthy dietary behaviors were found to be associated with an increased risk of developing cardiometabolic multimorbidity and this association differed between genders. Several common lifestyle and dietary behavior patterns suggest that patients with cardiometabolic multimorbidity may achieve better health outcomes if those with certain high-risk lifestyle patterns are identified and managed.
Antimicrobial Resistance and Pathogenicity of Aliarcobacter butzleri Isolated from Poultry Meat
Authors: Oliveira Maria Gabriela Xavier de , Cunha Marcos Paulo Vieira , Moreno Luisa Zanolli , Saidenberg André Becker Simões , Vieira Mônica Aparecida Midolli , Gomes Tânia Aparecida Tardelli , Moreno Andrea Micke , Knöbl Terezinha 
Published: February 2023

Aliarcobacter butzleri (A. butzleri) is an emergent zoonotic food-related pathogen that can be transmitted through the consumption of poultry meat. Data regarding the pathogenicity and resistance of A. butzleri are still scarce, and the presence of virulent MDR strains of this zoonotic pathogen in poultry meat is an issue of particular concern to public health. This study aimed to characterize the pathogenicity and antimicrobial resistance profiles of A. butzleri strains isolated from poultry meat sold at retail markets in São Paulo, Brazil. The minimum inhibitory concentrations of 27 strains were determined using the broth microdilution method. The results showed that 77.7% of the isolates were resistant to clindamycin, 62.9% to florfenicol, 59.2% to nalidixic acid, 11.1% to azithromycin, 7.4% to ciprofloxacin and telithromycin, and 3.7% to erythromycin and tetracycline, although all were susceptible to gentamicin. Moreover, 55.5% of the virulent isolates were also multidrug-resistant (MDR). Three strains were selected for pathogenicity tests in vitro and in vivo. The tested strains expressed weak/moderate biofilm production and showed a diffuse adhesion pattern (3 h) in HeLa cells and toxicity in Vero cells (24 h). Experimental inoculation in 11-week-old chicks induced a transitory inflammatory enteritis. Intestinal hemorrhage and destruction of the intestinal crypts were observed in the rabbit ileal loop test. Considering the fact that Brazil is a major exporter of poultry meat, the data from this study point to the need of improvement of the diagnostic tools, as well as of the adoption of surveillance guidelines and more specific control strategies to ensure food safety, reducing the presence of pathogenic MDR strains in broilers.
Parameter Estimation of a Grid-Tied Inverter Using In Situ Pseudo-Random Perturbation Sources
Authors: Gerber Ian Paul , Mwaniki Fredrick Mukundi , Vermeulen Hendrik Johannes 
Published: February 2023

Inverters are playing an increasingly important role in the electrical utility grid due to the proliferation of renewable energy sources. Obtaining inverter models with accurate parameters is, therefore, essential for grid studies and design. In this paper, a methodology to estimate the output impedance and parameters of a residential grid-tied inverter is proposed. The methodology is first verified through simulation. A sensitivity analysis is conducted to determine the influence of the filter and controller parameters on the output impedance of the inverter. The simulated output impedance, voltage, and current are used in a parameter estimation methodology to obtain filter and controller parameters. It is shown that up to seven parameters can be estimated accurately. The proposed methodology is further investigated through a practical experiment. Two perturbation sources, the pseudo-random binary sequence perturbation and pseudo-random impulse sequence perturbation, are used, in turn, to perturb a residential grid-tied inverter that delivers up to 1.6 kW with the aim of obtaining its output impedance. The output impedances obtained through both pseudo-random sources are compared. It is shown that a pseudo-random binary sequence perturbation source applied in series between the grid and the inverter under test allows for the best estimation of the grid-tied inverter’s output impedance. A black-box modeling approach aimed at estimating an analytical transfer function of the output impedance from experimental data is also discussed.
New Synthetic Operon Vectors for Expressing Multiple Proteins in the Chlamydomonas reinhardtii Chloroplast
Authors: Yeon Jihye , Miller Stephen M. , Dejtisakdi Wipawee 
Published: February 2023

Microalgae are a promising platform for generating valuable commercial products, including proteins that may not express well in more traditional cell culture systems. In the model green alga Chlamydomonas reinhardtii, transgenic proteins can be expressed from either the nuclear or chloroplast genome. Expression in the chloroplast has several advantages, but technology is not yet well developed for expressing multiple transgenic proteins simultaneously. Here, we developed new synthetic operon vectors to express multiple proteins from a single chloroplast transcription unit. We modified an existing chloroplast expression vector to contain intercistronic elements derived from cyanobacterial and tobacco operons and tested the ability of the resulting operon vectors to express two or three different proteins at a time. All operons containing two of the coding sequences (for C. reinhardtii FBP1 and atpB) expressed the products of those genes, but operons containing the other two coding sequences (C. reinhardtii FBA1 and the synthetic camelid antibody gene VHH) did not. These results expand the repertoire of intercistronic spacers that can function in the C. reinhardtii chloroplast, but they also suggest that some coding sequences do not function well in the context of synthetic operons in this alga.
Design, Synthesis, Antifungal Activity, and Molecular Docking of Streptochlorin Derivatives Containing the Nitrile Group
Authors: Liu Jing-Rui , Gao Ya , Jin Bing , Guo Dale , Deng Fang , Bian Qiang , Zhang Hai-Feng , Han Xin-Ya , Ali Abdallah S. , Zhang Ming-Zhi , Zhang Wei-Hua , Gu Yu-Cheng 
Published: February 2023

Based on the structures of natural products streptochlorin and pimprinine derived from marine or soil microorganisms, a series of streptochlorin derivatives containing the nitrile group were designed and synthesized through acylation and oxidative annulation. Evaluation for antifungal activity showed that compound 3a could be regarded as the most promising candidate—it demonstrated over 85% growth inhibition against Botrytis cinerea, Gibberella zeae, and Colletotrichum lagenarium, as well as a broad antifungal spectrum in primary screening at the concentration of 50 μg/mL. The SAR study revealed that non-substituent or alkyl substituent at the 2-position of oxazole ring were favorable for antifungal activity, while aryl and monosubstituted aryl were detrimental to activity. Molecular docking models indicated that 3a formed hydrogen bonds and hydrophobic interactions with Leucyl-tRNA Synthetase, offering a perspective for the possible mechanism of action for antifungal activity of the target compounds.
Revisión bibliográfica: manejo del abdomen agudo por trauma cerrado en pacientes pediátricos
Authors: Mauricio Pin Ponce Rodney , Moran Astrid Elizabeth Arreaga , Alejandro Coello Vera Manuel , Vera Angel Andrés Plúas , Gabriela Vera Fiallos Karem , Stefania Villafañe Quintero , Daniel Ponce Ricardo Otton , Escobar Kissy Moreno 
Published: February 2023

En la población pediátrica el traumatismo se ubica en la segunda causa con elevado índice de mortalidad después del traumatismo craneoencefálico. Entendemos la importancia de una revisión bibliográfica para lograr un rápido diagnóstico y manejo adecuado, de esta manera logrando disminuir las tasas de mortalidad. Dentro de las causas más frecuentes de traumatismo abdominal pediátrico están los accidentes de tránsito, caídas de alturas, golpes directos sobre órganos abdominales.
Associação do tratamento alopático e homeopático em mastocitoma cutâneo em cão- relato de caso
Authors: De Melo Renata Gabriela Ambrosina Silva , Santos Renan Felipe Silva , Van der Linden Lais Albuquerque , Das Chagas Maíra Maria Meira , Silva Flaviane Maria Florêncio Monteiro , De Lima Helvio Rodrigues , Farias Eulina Tereza Nery , De Lima Evilda Rodrigues 
Published: February 2023

O mastocitoma cutâneo é o tumor de pele de maior prevalência em cães com idade entre 8 e 10 anos de comportamento agressivo, com metástase generalizada, de curso rápido, levando muitas vezes o animal a óbito. Diante disso, esse estudo tem como objetivo descrever um relato de caso acerca da homeopatia inserida na terapia complementar em pacientes veterinários oncológicos, tendo como intuito, reunir e identificar os benefícios dessa terapia na remissão tumoral, diminuição dos efeitos adversos provocados pela doença e pela terapia convencional. Foi atendido um animal da espécie canina, fêmea, sem raça definida, de oito anos de idade, apresentando um nódulo único, não ulcerado, aderido, de aproximadamente 2cm de diâmetro. O diagnóstico do mastocitoma foi baseado na citologia e no exame histopatológico da lesão. Em histopatológico foi confirmado Mastocitoma grau III (Patnaik)/grau elevado (Kiupel), caracterizando prognóstico reservado para o quadro. Foi utilizado vimblastina na dose de 2mg/m2, injetável, uma vez na semana por 12 semanas e prednisona na dose de 1mg/kg por via oral totalizando 12 semanas e o Viscum album por via oral na dose de cinco glóbulos três vezes por dia durante seis meses. Foi observado que a utilização desta planta proporcionou melhor qualidade de vida ao animal durante o tratamento quimioterápico afim de evitar o surgimento de metástases a curto prazo e a longo prazo.
Evaluation of the pathogenicity of entomopathogenic fungi isolated from the larvae of the corn stem borer Diatraea grandiosella Dyar (Lepidoptera: crambidae)
Authors: Martínez José Antonio Ramos , Martínez Néstor Bautista , Franco Ariel W. Guzmán , Maciel J. Concepción Rodríguez , Arriaga Francisco Javier Trujillo , Mejía Fernando Tamayo , Loé Javier Hurtado , Zacarías Pedro Eduardo Moreno 
Published: February 2023

Los barrenadores del tallo del género Diatraea son plagas importantes en el cultivo del maíz (Zea mays L.) debido a la dificultad que se tiene en su manejo, ya que éstas barrenan el tallo de la planta y es difícil de presenciar su daño. Los hongos entomopatógenos constituyen una opción para su manejo. Se evaluó la patogenicidad de dos cepas de Beauveria bassiana (BbP 001 y BbP 002) y una de Metarhizium rileyi (MrP 001) con el objetivo de seleccionar la más patogenica sobre larvas del cuarto instar de Diatraea grandiosella. Para determinar la patogenicidad de estas cepas, se empleó una concentración de 1x108 esporas mL-1 para lo cual se utilizó un diseño experimental completamente al azar con cuatro repeticiones, aplicando los tratamientos sobre trozos de tallos de maíz de 5 cm de longitud para posteriormente colocarles una larva a cada tallo (12 tallos y larvas por cada repetición, en total 48 larvas por tratamiento). La mortalidad se analizó mediante un ANOVA y una prueba de Tukey donde se observaron diferencias significativas (α = 0,05) entre los tratamientos, en el cual se presentó un porcentaje de mortalidad del 71%, 50%, 27% ocasionado por las cepas BbP 001, BbP 002, MrP 001 respectivamente. Se seleccionaron las cepas de B. bassiana para determinar la concentración letal 50 mediante un análisis PROBIT con el paquete estadístico SAS 9.0, se evaluaron las concentraciones (conidios mL-1) de 1x106, 1x107, 1x108, 4x108 y 7x108, la cepa más patogénica fue la BbP 001 presentando una CL 50 de 1.8x107 y una CL 90 de 1.3x109, mientras que la cepa BbP 002 fue menos patogénica con una CL 50 de 7.2x108 y una CL90 de 4.5x109. Con base en estos resultados se concluyó que existen hongos entomopatógenos presentes en forma natural que infectan a las larvas de D. grandioella que pueden ser aislados para emplearlos como fuente de control biológico.
Natrinai Based on the Narrative Songs of Tholkaappiyam
Authors: S Sundari , N Dhanarajan , L Bommi 
Published: February 2023

Tolkaappiyam is a comprehensive text on grammar which contains total 1610 sutras in the nurpa meter, it contains three books such as letters, words and subject matter. Tholkaappiyar has explained about the various types of claims both internal and external in subject matter. In particular, he points out the narration in the 15th song out of 34 songs. This article explains the way in which Natrinai songs are composed with special interpretations called narrations. M.S. Rabising explains narrations as follows. A narration where one of the characters is speaking directly to the audience is called poetry. Subjective songs are classified as ``Talaivan Kootru'', a song that sounds like a boy speaking, and ``Thozhi Kootru'', a song that sounds like a friend speaking. In Tiruvalluvar's Kamathuppal, this type of narration or conversationis very famous. In subjective literature, the hero and the heroine are the main character for narration. Therefore, this article reveals the manner in which the narrators follow the internal norms by analyzing the hymns from the perspective of the performers during the times of love making.
MODEL BELAJAR TEKNIK DASAR PENJAGA GAWANG HOCKEY PEMULA PADA PESERTA EKSTRAKURIKULER TINGKAT SEKOLAH MENENGAH ATAS
Authors: Sari Ira Permata , Sari Eka Fitri Novita , Nurulfa Rizky , Sari Zihan Novita 
Published: February 2023

Penelitian ini bertujuan mengembangan variasi model belajar teknik dasar penjaga gawang hockey pemula pada peserta ekstrakurikuler tingkat sekolah menengah atas diharapkan dapat menjadi bentuk pembelajaran yang menyenangkan dan menarik bagi siswa dalam mengikuti kegiatan ekstrakurikuler hockey, sehingga dapat menghilangkan kebosanan dan kejenuhandalam proses pembelajaran. Metode Penelitian ini menggunakan RND dengan model pengembangan ADDIE yang akan menghasilkan produk berupa desain pembelajaran. Model ADDIE memiliki lima Tahapan yaitu sebagai berikut: (1) analisis, (2) perancangan, (3) pengembangan, (4) implementasi, (5) evaluasi. Tahap awal Variasi model belajar teknik dasar penjaga gawang hockey menggunakan 27 model kemudian di validasi oleh ahli menjadi 25 model yang layak, tempat Penelitian menggunakan 4 sekolah di Kab Tanggerang dengan jumlah Subyek 12 siswa di masing-masing sekolah, dengan hasil 95 % dinyatakan sangat baikModel belajar pada teknik dasar penjaga gawang hockey, untuk hasil ketertarikan siswa dalam mengikuti ekstrakurikuler 98,6 % dinyatakan sangat baik untuk pemula pada siswa ekstrakurikuler tingkat sekolah menengah. datas ini dapat dijadikan referensi bagi guru, Pembina, dan pelatih hockey sebagai proses pembelajaran khususnya penjaga gawang. Hasil penelitian ini dapat disimpulkan bahwa setelah melalui uji validasi dengan justifikasi ahli, menghasilkan produk model belajar teknik dasar penjaga gawang hockey pemula pada peserta ekstrakurikuler tingkat sekolah menengahatas sebanyak 25 model.