bluuebunny/crossref_metadata_2025_split huggingface dataset:
Imaging in patients with ST-segment elevation myocardial infarction - a case report
Authors: Gniot Marcelina , Jankiewicz Marek 
Published: March 2023

Introduction and purpose: Intravascular ultrasound (IVUS) facilitates 3-dimensional visualization of the blood vessels. Nowadays, it becomes increasingly supportive in percutaneous coronary intervention (PCI) guiding in patients with acute myocardial infarction (AMI). This report presents IVUS-guided PCI performed on 43-year-old patient with ST-segment elevation myocardial infarction (STEMI).
Brief description of the state of knowledge: IVUS is an established intracoronary imaging technique that can be used in patients with AMI. It allows assessment of the plaque nature, stent selection and optmisation. An increasing body of evidence shows that IVUS-guided PCI is correlated with reduction in number of major adverse cardiovascular events (MACE), stent thrombosis and with less contrast use. Studies show, that IVUS can be used in patient with STEMI, as it is presented in this report.
Conclusion: This case illustrates IVUS-guided PCI performed on the patient with STEMI. It shows that it is crucial to consider using this technique in every patient with AMI, as it provides beneficial outcome of the treatment. It is particularly important in patients with complicated anatomy of the blood vessels and in patients with contraindications to the considerable contrast use.
Kidney Stones - What should You know?
Authors: Szymańska Ewa , Ostaszewska Sandra , Świąder Kinga , Augustynowicz Kinga , Chrzanowski Jakub 
Published: March 2023

Introduction: Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or attached to the renal papillae. The risk of developing kidney stones is 10 to 15 percent in the United States and Europe, although this number is trending higher. Contributing risk factors for kidney stones are obesity, insulin resistance, gastrointestinal pathology, living in warmer climates, certain dietary patterns and medications. In this article we reviewed the epidemiology, symptoms and treatment of acute and chronic kidney stones and also prevention of stones formation in urinary tract. Material and methods: The work was based on medical articles collected in PubMed, websites and medical books. The research was conducted by looking at keywords such as: "Kidney Stones", "Renal Colic" and “Rirs”.

Conclusions: The interdisciplinary approach, education of the patient and multiple endourological techniques can provide us with many solutions in the treatment of this contition.

Doctors should adjust treatment to provide the best therapeutic effects.
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors
Authors: Bai Zhibiao , Shou Zeyu , Hu Kai , Yu Jiahuan , Meng Hongming , Chen Chun 
Published: March 2023

AimsThis study was performed to explore the effect of melatonin on pyroptosis in nucleus pulposus cells (NPCs) and the underlying mechanism of that effect.MethodsThis experiment included three patients diagnosed with lumbar disc herniation who failed conservative treatment. Nucleus pulposus tissue was isolated from these patients when they underwent surgical intervention, and primary NPCs were isolated and cultured. Western blotting, reverse transcription polymerase chain reaction, fluorescence staining, and other methods were used to detect changes in related signalling pathways and the ability of cells to resist pyroptosis.ResultsWestern blot analysis confirmed the expression of cleaved CASP-1 and melatonin receptor (MT-1A-R) in NPCs. The cultured NPCs were identified by detecting the expression of CD24, collagen type II, and aggrecan. After treatment with hydrogen peroxide, the pyroptosis-related proteins NLR family pyrin domain containing 3 (NLRP3), cleaved CASP-1, N-terminal fragment of gasdermin D (GSDMD-N), interleukin (IL)-18, and IL-1β in NPCs were upregulated, and the number of propidium iodide (PI)-positive cells was also increased, which was able to be alleviated by pretreatment with melatonin. The protective effect of melatonin on pyroptosis was blunted by both the melatonin receptor antagonist luzindole and the nuclear factor erythroid 2–related factor 2 (Nrf2) inhibitor ML385. In addition, the expression of the transcription factor Nrf2 was up- or downregulated when the melatonin receptor was activated or blocked by melatonin or luzindole, respectively.ConclusionMelatonin protects NPCs against reactive oxygen species-induced pyroptosis by upregulating the transcription factor Nrf2 via melatonin receptors.Cite this article:Bone Joint Res 2023;12(3):202–211.
Hybrid spatial–temporal Mueller matrix imaging spectropolarimeter for high throughput plant phenotyping
Authors: Kudenov Michael W. , Krafft Danny , Scarboro Clifton G. , Doherty Colleen J. , Balint-Kurti Peter 
Published: March 2023

Many correlations exist between
spectral reflectance or transmission with various phenotypic responses
from plants. Of interest to us are metabolic characteristics, namely,
how the various polarimetric components of plants may correlate to
underlying environmental, metabolic, and genotypic differences among
different varieties within a given species, as conducted during large
field experimental trials. In this paper, we overview a portable
Mueller matrix imaging spectropolarimeter, optimized for field use, by
combining a temporal and spatial modulation scheme. Key aspects of the
design include minimizing the measurement time while maximizing the
signal-to-noise ratio by mitigating systematic error. This was
achieved while maintaining an imaging capability across multiple
measurement wavelengths, spanning the blue to near-infrared spectral
region (405–730 nm). To this end, we present our optimization
procedure, simulations, and calibration methods. Validation results,
which were taken in redundant and non-redundant measurement
configurations, indicated that the polarimeter provides average
absolute errors of (5.3±2.2)×10−3 and (7.1±3.1)×10−3, respectively. Finally, we provide
preliminary field data (depolarization, retardance, and diattenuation)
to establish baselines of barren and non-barren Zea maize hybrids (G90 variety), as captured from various
leaf and canopy positions during our summer 2022 field experiments.
Results indicate that subtle variations in retardance and
diattenuation versus leaf canopy position may be present before they
are clearly visible in the spectral transmission.
Serum fetuin-A is decreased in cirrhotic patients with Wilson’s disease
Authors: Vörös Krisztián , Márkus Bernadett , Atzél Klára , Szalay Ferenc , Gráf László , Németh Dániel , Masszi Tamás , Torzsa Péter , Kalabay László 
Published: March 2023

Introduction
Wilson’s disease may lead to cirrhosis, but timely medical treatment could slow down its progression. Clinical markers helping early diagnosis are essential. Decreased fetuin-A concentration has been reported in cirrhosis of different etiologies. The aim of this study was to investigate whether decreased serum fetuin-A concentration could identify patients with Wilson’s disease who developed cirrhosis.

Materials and methods
In this cross-sectional study we determined the serum fetuin-A concentration of 50 patients with Wilson’s disease. We analyzed the data of patients with liver involvement, comparing cirrhotic and non-cirrhotic patients.

Results
Among patients with liver involvement those with cirrhosis had significantly lower fetuin-A and albumin level, white blood cell and platelet count. Fetuin-A negatively correlated with disease duration, bilirubin level, positively with total protein and albumin concentration, but not with copper and ceruloplasmin concentrations or markers of systemic inflammation. In multivariate analysis with fetuin-A and the Nazer score or its parameters only fetuin-A was a significant determinant of having cirrhosis. In receiver operator curve analysis among patients with liver involvement the fetuin-A level of 523 μg/ml was associated with cirrhosis with 82% sensitivity and 87% specificity. The presence of the H1069Q mutation was not associated with alteration in fetuin-A concentration.

Conclusions
The serum concentration of fetuin-A is a sensitive marker of liver cirrhosis in Wilson’s disease, independently of the H1069Q mutation, ceruloplasmin concentration or systemic inflammation.
Alluring Monsters: The Pontianak and Cinemas of Decolonization, Rosalind Galt (2021)
Authors: Mather Philippe 
Published: March 2023

Review of: Alluring Monsters: The Pontianak and Cinemas of Decolonization, Rosalind Galt (2021)
New York: Columbia University Press, 312 pp.,
ISBN 978-0-23120-133-9, p/bk, $35.00
Contesting Cyberspace in China: Online Expression and Authoritarian Resilience, Rongbin Han (2018)
Zoning China: Online Video, Popular Culture, and the State, Luzhou Li (2019)
Authors: Moskowitz Marc L. 
Published: March 2023

Review of: Contesting Cyberspace in China: Online Expression and Authoritarian Resilience, Rongbin Han (2018)
New York: Columbia University Press, 315 pp.,
ISBN 978-0-23118-475-5, p/bk, $32.00

Zoning China: Online Video, Popular Culture, and the State, Luzhou Li (2019)
Boston, MA: MIT Press, 296 pp.,
ISBN 978-0-26204-317-5, h/bk, $40.00
Clinical value of multi-omics-based biomarker signatures in inflammatory bowel diseases: challenges and opportunities
Authors: Bourgonje Arno R. , van Goor Harry , Faber Klaas Nico , Dijkstra Gerard 
Published: March 2023

Abstract
Inflammatory bowel diseases (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), are complex and heterogeneous diseases characterized by a multifactorial etiology, therefore demanding a multimodal approach to disentangle the main pathophysiological components driving disease onset and progression. Adoption of a systems biology approach is increasingly advocated with the advent of multi-omics profiling technologies, aiming to improve disease classification, to identify disease biomarkers and to accelerate drug discovery for patients with IBD. However, clinical translation of multi-omics-derived biomarker signatures is lagging behind, since there are several obstacles that need to be addressed in order to realize clinically useful signatures. Multi-omics integration and IBD-specific identification of molecular networks, standardization and clearly defined outcomes, strategies to tackle cohort heterogeneity, and external validation of multi-omics-based signatures are critical aspects. While striving for personalized medicine in IBD, careful consideration of these aspects is however needed to adequately match biomarker targets (e.g. the gut microbiome, immunity or oxidative stress) with their corresponding utilities (e.g. early disease detection, endoscopic and clinical outcome). Theory-driven disease classifications and predictions are still governing clinical practice, while this could be improved by adopting an unbiased, data-driven approach relying on molecular data structures integrated with patient and disease characteristics. In the foreseeable future, the main challenge will lie in the complexity and impracticality of implementing multi-omics-based signatures into clinical practice. Still, this could be achieved by developing easy-to-use, robust and cost-effective tools incorporating omics-derived predictive signatures and through the design and execution of prospective, longitudinal, biomarker-stratified clinical trials.
Bilingual education in China: a qualitative synthesis of research on models and perceptions
Authors: Liu Qi , Chong Sin Wang 
Published: March 2023

Abstract
Bilingual education has become increasingly popular in China, with a subsequent growth in research, particularly research with a qualitative component that examines learners’ and teachers’ experiences and perspectives. These studies have mostly been conducted in individual classroom settings where contexts and learners differ, making findings less transferrable to other educational settings. To address this need, we conducted a qualitative synthesis of research that aims to provide a holistic and rich description of bilingual education in China. Our focus is on the implementation of bilingual education in different educational contexts, learners’ and teachers’ perceptions of bilingual education, and the research instruments used for the evaluation of bilingual education. Following a discipline-specific methodological framework for conducting qualitative research synthesis (Chong, Sin Wang & Luke Plonsky. 2021. A primer on qualitative research synthesis in TESOL. TESOL Quarterly 55(3). 1024–1034), we identified suitable studies using a pre-determined search string within various databases. Search results were screened based on a set of inclusion criteria and relevant information was extracted from the included studies using a piloted data extraction form. The extracted data were synthesised using grounded theory to identify new themes and sub-themes. Our findings point to the need for more fine-grained classifications of bilingual education models, despite the fact that Chinese learners generally show positive attitudes towards bilingual education. The study ends with an analysis of limitations, as well as recommendations for future research and practice.
Impact of AMSU-A and MHS radiances assimilation on Typhoon Megi (2016) forecasting
Authors: Liu Chaoshun , Gong Junqiang 
Published: March 2023

Abstract
To better understand the assimilation contribution and influence mechanism of different satellite platforms and different microwave instruments, the radiance data of Advanced Microwave Sounding Unit-A (AMSU-A) and the Microwave Humidity Sounder (MHS) onboard NOAA-15 and NOAA-18 are assimilated to investigate various assimilation effects on the prediction of path and intensity of Typhoon Megi (2016) based on Weather Research and Forecasting (WRF) three-dimensional variation and the WRF model. The community radiative transfer model is employed as the forward operator. The quality control and bias correction procedures before the radiance data assimilation (DA) are performed to improve the simulations.
Impact of AMSU-A and MHS radiances assimilation on Typhoon Megi (2016)’s path and intensity is investigated by six experiments (without and with AMSU-A and MHS DA) with initial conditions at 1200 UTC on 25 September 2016 and 60 h forecast integration.
The results are compared to the observational data from the China Meteorological Administration tropical cyclone database. The impact mechanisms of DA adjustments to the initial fields and assimilation increment analysis of each physical quantity field are investigated in detail. The findings show that NOAA-15 AMSU-A assimilation produces the best output over the course of the 60 h simulation, demonstrating that assimilation satellite data from multiple platforms is not always better than assimilation satellite data from a single platform. In comparison, MHS assimilation has a favorable effect on short-term path and strength forecasts, but has a negative impact on long-term forecasts. The effect of MHS DA needs to be further investigated.
Optimization-based control strategy for a large-scale polyhydroxyalkanoates production in a fed-batch bioreactor using a coupled PDE–ODE system
Authors: Tawai Atthasit , Sriariyanun Malinee , Panjapornpon Chanin 
Published: March 2023

Abstract
Control strategy development for fed-batch bioreactor (FBBR) plays an important role in the improvement of polyhydroxyalkanoate (PHA) production. To develop a feeding strategy for PHA production in a large-scale FBBR, an optimization-based control scheme that considers nutrient dispersion is proposed in this work. A coupled partial differential equations and ordinary differential equation model is proposed to describe the axial-dispersed nutrient and well-dispersed microbial dynamics with process constraints. An analytical model predictive control (AMPC) method that applies integrated variables of nutrients is employed to develop the real-time control system. The control objective is to regulate the PHA concentration at the updated set points by adjusting the nutrient feed rates; a process disturbance is introduced to evaluate the control robustness. Simulation experiments of a fed-batch operation are conducted to investigate the performance of the developed controller; the controlled output is designed to track the updated set points corresponding to the biomass concentration. Results of closed-loop and regulatory systems showed that the proposed control strategy could provide more productivity (33–38%) compared to the applied PI controller. The performance test demonstrates that the developed control system could apply the biomass concentration for updating set points, provide the optimal control actions that promote PHB accumulation and handle the disturbance effectively.
Does God Micromanage the World? Learning about the Cosmos from the Book of Job
Authors: Jančovič Jozef 
Published: March 2023

Abstract
The biblical book of Job contains more extensive discussion of the cosmos and God’s role in it than any other book in the Bible with the possible exception of Psalms. The main issue of the book is God’s justice towards the sorely tried protagonist, Job. The major distinction between the book of Job and the thinking of the general ancient Near Eastern culture is the role of God’s justice and wisdom in the operations of the cosmos. This paper will focus on the key passages about the cosmos in Job in order to define the specific message of the book concerning the relations of God and men to the world, and determine how the book of Job views a control of the world in the overall context of the book. First, we will consider the context and structure of the book. Then the passages about the cosmos and creation themselves will be summarized in an attempt to determine what they are communicating, especially in regard to God’s control of the world. Finally, we will draw conclusions about the overall role that biblical creation imagery plays in the drama of Job.
Effects of boron waste as a reinforcement in the production of Al composite foams
Authors: Kılıç Gökçe , Körpe Neşe Öztürk 
Published: March 2023

Abstract
In this study, the effect of using boron products in the production of aluminium composite foam on the formation of pores and mechanical properties of the material was investigated. Metallic foam was produced by powder metallurgy method by adding borogypsum to the Al matrix and using boric acid (H3BO3) as a pore former. Samples containing 5, 10 and 20 wt% borogypsum were prepared at initial pressing pressures of 420 MPa and 630 MPa and sintered at 550 °C for 3 h. As a result of microhardness measurements taken from the cell wall of foam samples with ∼40% porosity, it was determined that the hardness value increased as the borogypsum ratio increased. According to the results of the quasi-static compression test performed at a deformation rate of 10−3 s−1 at room temperature, the hardness and strength values of 20 wt% borogypsum reinforced Al composite foam prepared at 630 MPa pressure increased. In addition, mechanical properties such as plateau tension and elastic modulus for each sample were theoretically determined with the Gibson–Ashby approach.
Investigation of glass/epoxy laminate composites reinforced with bio-particles under mechanical loading
Authors: Kandas Halis , Ozdemir Okan 
Published: March 2023

Abstract
In this paper, the effects of particle reinforcement on the tensile, compression and flexural properties, as well as the influence of cross head speed on the quasi-static punch shear properties of glass/epoxy composites are investigated. Laminated composites, which are manufactured by hand lay-up method consist of six layers of stitched glass fibers. As the particle reinforcement materials, pinecone and acorn powders with 1, 2, 3, 4 and 5 wt% ratios are used for the manufacturing of composites. The quasi-static punch shear behaviour of composites is elucidated at a room temperature through the force – deformation curves and the energy graphs at different test speeds (i.e., 1, 10 and 20 mm min−1). According to the experimental findings of quasi-static punch shear tests, it is concluded that the maximum contact force of each composite increases along with the punch shear test speed. Compressive strength of the acorn reinforced specimens shows their highest compressive value at the particle amount of 5 wt%, while pinecone-reinforced composites exhibit their highest compressive strength at the particle ratio of 2 wt%.
Meta-analysis of the influence of the substitution of maize with cassava on performance indices of broiler chickens
Authors: Ogbuewu Ifeanyi Princewill , Mbajiorgu Christian Anayo 
Published: March 2023

Abstract
There are growing numbers of publications on the effect of substitution of maize with cassava (Manihot esculenta Crantz) on growth indices of broiler chickens with variable results. The purpose of this meta-analysis was to explore the influence of substitution of maize with dietary cassava on growth traits (i.e., average daily feed intake [ADFI], body weight gain [BWG] and feed conversion efficiency [FCE]) of broilers. Search done in PubMed, Google scholar and Scopus databases yielded 303 studies of which 27 were suitable for the analysis. Heterogeneity was explored by subgroup and meta-regression analyses using the following moderator variables: publication year, study continent, processing methods, cassava form, substitution level, broiler strain, number of birds per groups and treatment durations. Results show that dietary cassava reduced ADFI (mean difference [MD] = −5.19 g/day; 95% confidence interval [CI]: −8.60, −1.79; I
2 = 99%) and BWG (MD = −8.49 g/day; 95% CI: −9.65, −7.33; I
2 = 98%) and increased FCE (MD = 0.29; 95% CI: 0.24, 0.35; I
2 = 99%) in broilers compared to controls. Publication year, broiler strain, treatment durations and substitution level) influenced the outcomes of the study and explained some of the sources of heterogeneity. In conclusion, our results suggested that dietary cassava inclusion at 5% (minimum) and 62% (maximum) reduced growth performance in broiler chickens. However, more effective methods for increasing the nutrient value of cassava roots for broiler chicken feeding as well as the cassava inclusion levels for optimal productivity are required.
How Local Communities Overcome Disaster and Crisis
Authors: Maeva Mila 
Published: March 2023

Abstract
The study considers disaster as a social phenomenon that affects individuals, communities, and societies. It focuses on a specific technological catastrophe—a train explosion in the village of Hitrino in Shumen region, Bulgaria, that killed seven, left 23 injured, and demolished 23 houses. The article describes and analyses the local community’s reactions based on fieldwork, i.e. ethnographic and sociological surveys conducted in 2018 to 2019. Attention is paid to the behaviour, management, and methods of coping with the short-term and long-term consequences of the disaster on individual, group, and institutional levels, as well as to the changes in social and ethnic relations. Hitrino is defined as a community in crisis in relation to the degree of its ability to develop a local strategy in advance, and due to the experience it accumulated. The study shows that disaster recovery strategies must include work with local communities which play a key role in reducing the negative impact of catastrophe.