bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unusual Transport Properties with In-plane Magnetic Field in SrxBi2Se3 Single Crystals
Authors: Zu Y. , Matsumae T. , Pyon S. , Tamegai T. 
Published: August 2023

Abstract
A topological insulator Bi2Se3 becomes a topological superconductor by doping Cu or Sr. Due to the nematicity of these Ax
Bi2Se3 (A = Cu, Sr) materials, physical quantities show two-fold rotational symmetry as a function of in-plane magnetic field angle φ despite their three-fold structural symmetry in the plane. In this study, single crystals of Sr
x
Bi2Se3 (0.0 ≤ x ≤ 0.17) were grown by the self-flux method. Using these crystals, extensive measurements of the magnetoresistivity as a function of φ (ρ(φ)) were performed. Angular dependence of magnetoresistance shows an unusual cos(φ) term, which can be related to the c-axis current as well as higher harmonics components. Origins of higher harmonics components of ρ(φ) are discussed.
Turbulent Structure and Characterization of ‘11’-type Iron-based Superconductors by Magneto-optical Imaging
Authors: Ren T , Sun Y , Pyon S , Tamegai T 
Published: August 2023

Abstract
Magneto-optical imaging is employed to investigate the vortex penetration modes in ‘11’-type iron-based superconductors (IBSs) Fe(Te0.6Se0.4) and FeSe single crystals. In Fe(Te0.6Se0.4), vortices penetrate mostly homogeneously from all edges, forming an unstable turbulent interface with pre-existing anti-vortices, where ‘Meissner hole’ emerges as those have been reported in ‘122’-type IBSs. In FeSe, however, the penetration is restricted to numerous mesoscopic stripe-like regions. Further experiments revealed an inhomogeneous vortex propagation pattern, where vortices are most likely to be channeled along the twin boundaries.
Current-voltage characteristics of 100-pixel 200-μm-square superconducting tunnel junction X-ray detector array
Authors: Shiki Shigetomo , Fujii Go 
Published: August 2023

Abstract
The superconducting tunnel junction (STJ) X-ray detector is an important tool for materials analysis because of its high energy resolution and high counting rate. In this work, the current-voltage (I-V) characteristics were investigated for a 100-pixel STJ array with a pixel size of 200 μm having a layer structure of Nb-Al/AlO
x
/Al-Nb and working at 0.3 K. The fabrication yield of the 200-μm STJ reached approximately 90%. A series of I-V curves for a single pixel in different cooling runs showed a discrete excess current, possibly due to the trapping of single fluxoids. With a reduction of the ambient magnetic field during cooling, larger STJ pixels can be used.
Thermal Characteristic Analysis of Fully Superconducting Motors Employing Dilute Gas Rotor Cooling Structure
Authors: Akasaka Kazuki , Terao Yutaka , Ohsaki Hiroyuki , Okai Keiichi , Taguchi Hideyuki 
Published: August 2023

Abstract
We have proposed a rotor cooling structure using dilute gas for a fully superconducting motor for aircraft application. Numerical analysis was performed to investigate the feasibility of the proposed cooling method and structure, which can make a fully superconducting motor lighter and more compact than a partially superconducting motor. The helium gas pressure in the gap, the rotor rotational speed, and the rotor loss are key parameters of the cooling, and thermal analysis was performed to clarify the dependence of the field winding temperature on these parameters. In the analysis, the motor model has the maximum output of 5.5 MW and the maximum speed of 5000 rpm. The superconducting armature windings are cooled down to 20 K by conduction cooling with liquid hydrogen, and the superconducting field winding is cooled down to about 50 K indirectly using helium gas in the gap. Numerical analysis results indicate that the helium gas pressure should be increased when the rotor loss is larger, but if the pressure is increased too much, the temperature of the field winding becomes higher due to wind loss. When the rotor loss is several hundred watts, the helium gas pressure should be in the range of 104 to 105 Pa.
Enhanced bone regeneration using Antheraea mylitta silk fibroin and chitosan based scaffold: in-vivo and in-vitro study
Authors: Ray Sambit , Nandi Samit Kumar , Dasgupta Sudip 
Published: August 2023

Abstract
In this study, highly interconnected porous scaffolds from Antheraea mylitta silk fibroin (SF) and chitosan (CH) were fabricated using the freeze-drying method. The weight ratios of SF to CH were varied from 90:10 (SF90/CH10) to 50:50 (SF50/CH50) to prepare the scaffolds from the aqueous suspension of the protein-polysaccharide mix. From the initial optimization of scaffold composition with respect to their microstructure, porosity, and mechanical properties, the SF80/CH20 scaffold exhibited the most suitable properties for bone tissue engineering application as compared to others compositions. Hence in-vitro hemocompatibility, protein adsorption, and MG-63 cell culture studies were carried out for SF80/CH20 scaffold. The fabricated SF80/CH20 scaffold showed a more controlled swelling percentage of 42.8%, with high BSA protein adsorption of 0.39 mg of BSA per gm of the scaffold at 24 h incubation period. Furthermore, in-vitro MG-63 cell culture study onto the fabricated SF80/CH20 scaffold elicited excellent MG-63 cell attachment with better biocompatibility and cell viability with increased F-action production from day 3 to day 7 of the cell culture period. In vivo bone defect healing in a rabbit tibia model revealed excellent bone healing capacity in SF80/CH20 scaffold implanted specimens compared to control ones, as evident from histology and fluorochrome labeling analysis.
Symmetric hypergraph states: entanglement quantification and robust Bell nonlocality
Authors: Nöller Jan , Gühne Otfried , Gachechiladze Mariami 
Published: August 2023

Abstract
Quantum hypergraph states are the natural generalization of graph states. Here we investigate and analytically quantify entanglement and nonlocality for large classes of quantum hypergraph states. More specifically, we connect the geometric measure of entanglement of symmetric hypergraphs to their local Pauli stabilizers. As a result we recognize the resemblance between symmetric graph states and symmetric hypergraph states. This explains both the exponentially increasing violation of local realism for infinitely many classes of hypergraph states and robustness towards particle loss.
Association Between Incident Type 2 Diabetes and Opium Use: Mediation by Body Mass and Adiposity
Authors: Nalini Mahdi , Poustchi Hossein , Roshandel Gholamreza , Kamangar Farin , Khoshnia Masoud , Gharavi Abdolsamad , Brennan Paul , Boffetta Paolo , Dawsey Sanford M , Abnet Christian C , Malekzadeh Reza , Etemadi Arash 
Published: August 2023

Abstract
Opiates can affect glucose metabolism and obesity, but no large prospective study (to our knowledge) has investigated the association between long-term opium use, body mass index (BMI; weight (kg)/height (m)2), and incident type 2 diabetes mellitus (T2DM). We analyzed prospective data from 50,045 Golestan Cohort Study participants in Iran (enrollment: 2004–2008). After excluding participants with preexisting diseases, including diabetes, we used adjusted Poisson regression models to estimate incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for T2DM in opium users compared with nonusers, using mediation analysis to assess the BMI-mediated association of opium use with incident T2DM. Of 40,083 included participants (mean age = 51.4 (standard deviation, 8.8) years; 56% female), 16% were opium users (median duration of use, 10 (interquartile range), 4–20) years). During follow-up (until January 2020), 5,342 incident T2DM cases were recorded, including 8.5% of opium users and 14.2% of nonusers. Opium use was associated with an overall decrease in incident T2DM (IRR = 0.83, 95% CI: 0.75, 0.92), with a significant dose-response association. Most (84.3%) of this association was mediated by low BMI or waist circumference, and opium use did not have a direct association with incident T2DM (IRR = 0.97, 95% CI: 0.87, 1.08). Long-term opium use was associated with lower incidence of T2DM, which was mediated by low body mass and adiposity.
Population Attributable Fraction of Nonvaccination of COVID-19 Due to Vaccine Hesitancy, United States, 2021
Authors: Nguyen Kimberly H , Zhao Ruitong , Chen Siyu , Vaish Akhil K , Bednarczyk Robert A , Vasudevan Lavanya 
Published: August 2023

Abstract
Understanding the extent of coronavirus disease 2019 (COVID-19) nonvaccination attributable to vaccine hesitancy versus other barriers can help prioritize approaches for increasing vaccination uptake. Using data from the Centers for Disease Control and Prevention’s Research and Development Survey, a nationally representative survey fielded from May 1 to June 30, 2021 (n = 5,458), we examined the adjusted population attribution fraction (PAF) of COVID-19 vaccine hesitancy attributed to nonvaccination according to sociodemographic characteristics and health-related variables. Overall, the adjusted PAF of nonvaccination attributed to vaccine hesitancy was 76.1%. The PAF was highest among adults who were ≥50 years of age (87.9%), were non-Hispanic White (83.7%), had a bachelor’s degree or higher (82.7%), had an annual household income of at least $75,000 (85.5%), were insured (82.4%), and had a usual place for health care (80.7%). The PAF was lower for those who were current smokers (65.3%) compared with never smokers (77.9%), those who had anxiety or depression (65.2%) compared with those who did not (80.1%), and those who had a disability (64.5%) compared with those who did not (79.2%). Disparities in PAF suggest areas for prioritization of efforts for intervention and development of messaging campaigns that address all barriers to uptake, including hesitancy and access, to advance health equity and protect individuals from COVID-19.
Validity and Reproducibility of a Semiquantitative Food Frequency Questionnaire for Measuring Intakes of Foods and Food Groups
Authors: Gu Xiao , Wang Dong D , Sampson Laura , Barnett Junaidah B , Rimm Eric B , Stampfer Meir J , Djousse Luc , Rosner Bernard , Willett Walter C 
Published: August 2023

Abstract
We evaluated the validity and reproducibility of a semiquantitative food frequency questionnaire (FFQ) for measuring intakes of 149 foods and 25 food groups among 736 participants of the Women’s Lifestyle Validation Study (WLVS, 2010–2012) and 649 participants of the Men’s Lifestyle Validation Study (MLVS, 2011–2013). Validity of the FFQ compared with two 7-day dietary records measured 6 months apart and the reproducibility between 2 FFQs administered 1 year apart (FFQ1 and FFQ2) were assessed using Spearman correlations and intraclass correlation coefficients. The average 1-year reproducibility of FFQ-measured foods was 0.64 in both the WLVS and MLVS. Reproducibility of the food groups (mean = 0.71 among women and 0.72 among men) was generally higher than that for individual foods. Among women, the average validity correlation for individual foods was 0.59 when comparing FFQ2 with the 7-day dietary records. Among men, the corresponding average validity correlation was 0.61. Compared with individual foods, food groups had slightly higher validity correlations in both women (range, 0.45–0.92; mean = 0.61) and men (range, 0.46–0.88; mean = 0.65). This study reaffirms that the FFQ performs well in measuring most foods and food groups and provides data to adjust for measurement errors in epidemiologic studies of foods and food groups.
Utilization rates and predictors of sodium glucose cotransporter 2 inhibitor use in patients with heart failure with or without type 2 diabetes
Authors: Bermudez Sarah R , Anderson Joe R , Bos Alexander J , Ray Gretchen M 
Published: August 2023

Abstract

Purpose
Sodium glucose cotransporter 2 (SGLT2) inhibitors have been demonstrated to reduce cardiovascular deaths and heart failure (HF) hospitalizations in patients with HF. Despite this, utilization remains low. The purpose of this study was to characterize SGLT2 inhibitor utilization rates and predictors of use in a population of patients with or without type 2 diabetes (T2D).

Methods
This was a retrospective, single-center, descriptive chart review study. Individuals 18 years of age or older with HF were eligible for inclusion. Charts were reviewed between August 2021 and February 2022. The primary objective was to identify rates of SGLT2 inhibitor prescribing for patients with HF within a large academic medical center. Logistic regression analyses were conducted to identify potential SGLT2 inhibitor utilization predictors (demographic characteristics, medical history, laboratory results, specialty provider visits, medication use, and medication coverage).

Results
A total of 800 patients with HF were included: 377 with HF with reduced ejection fraction (HFrEF), 88 with mildly reduced EF, and 335 with preserved EF. Key baseline characteristics were as follows: 43% female; 47% Hispanic; 42% with T2D; 49% with established atherosclerotic cardiovascular disease; and mean age, 65 years. SGLT2 inhibitor utilization was 6.5% overall. Key predictors of utilization were as follows: T2D (odds ratio [OR], 33.4; 95% CI, 8.01-139.55), HFrEF (OR, 2.8; 95% CI, 1.45-5.51), HF clinic visit (OR, 2.5; 95% CI, 1.40-4.60), visit with pharmacist with prescriptive authority (OR, 5.8; 95% CI, 3.14-10.88), and enrollment in the hospital patient assistance program (OR, 2.3; 95% CI, 1.08-4.97).

Conclusion
Despite guideline recommendations, SGLT2 inhibitors are underutilized in patients with HF with or without T2D.
A Cohort Analysis of Early Outcomes After AlloDerm, FlexHD, and SurgiMend Use in Two-Stage Prepectoral Breast Reconstruction
Authors: Chu Jacqueline J , Nelson Jonas A , Kokosis George , Haglich Kathryn , McKernan Cayla D , Rubenstein Robyn , Vingan Perri S , Allen Robert J , Coriddi Michelle R , Dayan Joseph H , Disa Joseph J , Mehrara Babak J , Matros Evan 
Published: August 2023

Abstract

Background
Acellular dermal matrix (ADM) is frequently utilized in prepectoral breast reconstruction, but few studies have examined the role of ADM type in complication risk.

Objectives
This study was performed to determine the impact of ADM type on early complication rates in 2-stage alloplastic prepectoral breast reconstruction.

Methods
We performed a cohort examination of all patients who underwent mastectomy with immediate 2-stage alloplastic prepectoral breast reconstruction with ADM support at Memorial Sloan Kettering Cancer Center from 2018 to 2021. ADM types utilized included AlloDerm (LifeCell Corporation, Branchburg, NJ), FlexHD (MTF Biologics, Edison, NJ), and SurgiMend (Integra LifeSciences Corporation, Princeton, NJ). Complication rates based on the number of tissue expanders (TEs) were determined for each ADM type. Performance of multivariate logistic regression determined the impact of ADM type on complication risk after accounting for confounders.

Results
Overall, 726 patients (1054 TEs: 194 AlloDerm, 93 FlexHD, 767 SurgiMend) were included. The 3 cohorts differed in terms of mastectomy type (nipple-sparing: 23.5% of AlloDerm, 33.3% of FlexHD, 19.1% of SurgiMend, P = .038); ADM perforation (perforated: 94.8% of AlloDerm, 98.2% of FlexHD, 100% of SurgiMend, P &lt; .001); and ADM size (AlloDerm: 153.2 cm2 [37.6], SurgiMend: 198.7 cm2 [10.4], FlexHD: 223.7 cm2 [37.9], P &lt; .001). On univariate examination, no differences existed between ADM types for seroma, infection, exposure, malposition, or TE loss. Additionally, after adjustment for confounders with multivariate regression, no ADM type had higher odds of TE loss.

Conclusions
In this large cohort of prepectoral reconstruction patients, ADM type did not significantly affect the risk of complications. Additional prospective studies are warranted to better evaluate ADM choice for prepectoral breast reconstruction.

Level of Evidence: 4
Submuscular Buttock Augmentation With Silicone Implants in 80 Female Patients
Authors: Elsaftawy Ahmed , Bonczar Tomasz , Stolarski Mateusz , Gabryszuk Kamil 
Published: August 2023

Abstract

Background
Over the past 4 decades, gluteal augmentation has increased enormously in popularity, and numerous techniques have been developed to provide patients with the best possible outcomes. The submuscular technique has been shown to be a reliable option for a broad cohort of patients.

Objectives
The main objective of this retrospective study was to describe the characteristics and clinical outcomes of a group of patients who underwent gluteal augmentation by the submuscular technique.

Methods
A retrospective analysis was conducted on 80 female patients who underwent submuscular gluteal augmentation with silicone implants between August 2019 and May 2022. All of the patients were operated on by the authors of the present study.

Results
Information about patient demographics, implants, complications, and treatments was analyzed. Moreover, the satisfaction of the patients was assessed by means of a short survey. The most frequent complication was wound dehiscence. Only 7 patients required surgical revisions, and 2 required isolated antibiotic therapy. All complications were effectively addressed and no implants had to be removed. Furthermore, the retrospective analysis revealed a noteworthy association between the size of the implant and the occurrence of complications.

Conclusions
The submuscular method provides the best aesthetic results and adequate safety for patients. It significantly minimizes the possibility of complications, such as fluid collection due to muscle fiber dissection or implant exposure/extrusion.

Level of Evidence: 4
iCpG-Pos: an accurate computational approach for identification of CpG sites using positional features on single-cell whole genome sequence data
Authors: Park Sehi , Rehman Mobeen Ur , Ullah Farman , Tayara Hilal , Chong Kil To 
Published: August 2023

Abstract

Motivation
The investigation of DNA methylation can shed light on the processes underlying human well-being and help determine overall human health. However, insufficient coverage makes it challenging to implement single-stranded DNA methylation sequencing technologies, highlighting the need for an efficient prediction model. Models are required to create an understanding of the underlying biological systems and to project single-cell (methylated) data accurately.

Results
In this study, we developed positional features for predicting CpG sites. Positional characteristics of the sequence are derived using data from CpG regions and the separation between nearby CpG sites. Multiple optimized classifiers and different ensemble learning approaches are evaluated. The OPTUNA framework is used to optimize the algorithms. The CatBoost algorithm followed by the stacking algorithm outperformed existing DNA methylation identifiers.

Availability and implementation
The data and methodologies used in this study are openly accessible to the research community. Researchers can access the positional features and algorithms used for predicting CpG site methylation patterns. To achieve superior performance, we employed the CatBoost algorithm followed by the stacking algorithm, which outperformed existing DNA methylation identifiers. The proposed iCpG-Pos approach utilizes only positional features, resulting in a substantial reduction in computational complexity compared to other known approaches for detecting CpG site methylation patterns. In conclusion, our study introduces a novel approach, iCpG-Pos, for predicting CpG site methylation patterns. By focusing on positional features, our model offers both accuracy and efficiency, making it a promising tool for advancing DNA methylation research and its applications in human health and well-being.
Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer’s disease mutations
Authors: Keramidis Iason , McAllister Brendan B , Bourbonnais Julien , Wang Feng , Isabel Dominique , Rezaei Edris , Sansonetti Romain , Degagne Phil , Hamel Justin P , Nazari Mojtaba , Inayat Samsoon , Dudley Jordan C , Barbeau Annie , Froux Lionel , Paquet Marie-Eve , Godin Antoine G , Mohajerani Majid H , De Koninck Yves 
Published: August 2023

Abstract
Disinhibition during early stages of Alzheimer's disease is postulated to cause network dysfunction and hyperexcitability leading to cognitive deficits. However, the underlying molecular mechanism remains unknown. Here we show that, in mouse lines carrying Alzheimer's disease-related mutations, a loss of neuronal membrane potassium-chloride cotransporter KCC2, responsible for maintaining the robustness of GABAA-mediated inhibition, occurs pre-symptomatically in the hippocampus and prefrontal cortex.
KCC2 downregulation was inversely correlated with the age-dependent increase in amyloid-β 42 (Aβ42). Acute administration of Aβ42 caused a downregulation of membrane KCC2. Loss of KCC2 resulted in impaired chloride homeostasis. Preventing the decrease in KCC2 using long term treatment with CLP290 protected against deterioration of learning and cortical hyperactivity. In addition, restoring KCC2, using short term CLP290 treatment, following the transporter reduction effectively reversed spatial memory deficits and social dysfunction, linking chloride dysregulation with Alzheimer's disease-related cognitive decline.
These results reveal KCC2 hypofunction as a viable target for treatment of Alzheimer's disease-related cognitive decline; they confirm target engagement, where the therapeutic intervention takes place, and its effectiveness.
Do Consumers Really Pay for SDGs? Re-Evaluating Consumer Behaviour Using Surveys in the USA, Germany, and Japan
Authors: Nakamura Eri , Nishitani Kimitaka , Mizutani Fumitoshi 
Published: August 2023

Abstract
This study investigates the relationship between consumers’ evaluation on sustainable development goal (SDG)-related characteristics and the actual payment for these values, while revealing effective governmental policies and business activities to enhance sustainable consumption. Using survey data from the USA, Germany, and Japan, the following results were obtained. First, the relative importance of the core element is 35–41% and that of the elements related to SDGs 8, 9, 12, and 13 dominates 52–58% of the overall product value. Second, effective approaches to enhance sustainable consumption differ among product characteristics. Third, lifestyle influences only the long-term and the medium-term goods. Fourth, while consumers rely on their experience in the choice of short-term goods, they make more deliberate decisions considering their condition factors for the medium-term and long-term goods. Based on these results, some practical implications were derived. First, active advertisement emphasizing the importance of economic aspects and actions for economic goals could be effective. Second, describing the idea that underlies the concept of SDGs could be effective rather than emphasizing each SDG. Third, incentive schemes focusing on daily goods rather than durable goods could enhance sustainable consumption further, as consumers still exhibit limited concern for daily goods. (JEL codes: D12; M20; M30; Q01; Q56; and Q58)