bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of inflammatory and infectious diseases of the pituitary gland in patients undergoing transsphenoidal surgery
Authors: Naser Paul Vincent , Papadopoulou Penelope , Teuber Jan , Kopf Stefan , Jesser Jessica , Unterberg Andreas W. , Beynon Christopher 
Published: June 2023

Abstract
Purpose
Inflammatory and infectious diseases of the pituitary gland (IIPD) are rare lesions often misdiagnosed preoperatively. Immediate surgery is indicated especially in cases of neurological impairment. However, (chronic) inflammatory processes can mimic other pituitary tumors, such as adenomas, and data on the preoperative diagnostic criteria for IIPD are sparse.

Methods
We retrospectively reviewed medical records of 1317 patients who underwent transsphenoidal surgery at our institution between March 2003 and January 2023. A total of 26 cases of histologically confirmed IIPD were identified. Patient records, laboratory parameters, and postoperative course were analyzed and compared with an age, sex, and tumor volume-matched control group of nonfunctioning pituitary adenomas.

Results
Pathology confirmed septic infection in ten cases, most commonly caused by bacteria (3/10) and fungi (2/10). In the aseptic group, lymphocytic hypophysitis (8/26) and granulomatous inflammation (3/26) were most frequently observed. Patients with IIPD commonly presented with endocrine and/or neurological dysfunction. No surgical mortality occurred. Preoperative radiographic findings (cystic/solid tumor mass, contrast enhancement) did not significantly differ between IIPD and adenomas. At follow-up, 13 patients required permanent hormone substitution.

Conclusion
In conclusion, correct preoperative diagnosis of IIPD remains challenging, as neither radiographic findings nor preoperative laboratory workup unequivocally identify these lesions. Surgical treatment facilitates decompression of supra- and parasellar structures. Furthermore, this low-morbidity procedure enables the identification of pathogens or inflammatory diseases requiring targeted medical treatment, which is crucial for these patients. Establishing a correct diagnosis through surgery and histopathological confirmation thus remains of utmost importance.
Follow-up von Menschen mit diabetischem Fußsyndrom sowie Trends von Amputationen in Deutschland und international
Authors: Kvitkina Tatjana , Claessen Heiner , Narres Maria , Icks Andrea 
Published: June 2023

ZusammenfassungFußkomplikationen bei Menschen mit Diabetes sind mit beeinträchtigter Lebensqualität, erhöhter Sterblichkeit und hohen Kosten verbunden. Rund 90 % der Betroffenen werden in hausärztlichen Praxen, weniger als die Hälfte in spezialisierten Fußambulanzen betreut. Es wird von einer inadäquaten Versorgung ausgegangen. Mögliche Gründe dafür sind Defizite bei der Umsetzung der Versorgungsempfehlungen, nicht berücksichtigte Bedürfnisse der PatientInnen sowie Barrieren bei der Kommunikation der verschiedenen beteiligten Akteure. Zudem spielt die aktive Beteiligung der Menschen mit Fußkomplikationen eine zentrale Rolle: Studienresultate deuten darauf hin, dass die Einbeziehung von PatientInnen in ein multidisziplinäres Versorgungsmodell mit häufiger Nachsorge und Patientenaufklärung dazu beitragen kann, das Risiko für Fußprobleme zu verringern. Die Lebensqualität stuften Menschen mit einer Fußläsion als insgesamt schlecht ein, mit eingeschränkter Mobilität und Schmerzen.Die Amputationsrate bei Menschen mit Diabetes sank über die Zeit signifikant, ist aber im Vergleich zu denjenigen ohne Diabetes immer noch deutlich erhöht. Der Rückgang der Amputationen könnte möglicherweise an einer Verbesserung der Versorgung und der Einführung neuer chirurgischer Technologien liegen. Im COVID-19-Pandemiejahr (COVID: „coronavirus disease“) 2020 zeigten sich im Vergleich zu den Jahren davor (2017–2019) eine signifikante Reduktion von Krankenhausaufenthalten mit diabetischen Fußproblemen, jedoch ein signifikanter Anstieg an Hospitalisierungen wegen Beinamputationen.Weitere Forschung sollte sich auf Basis praxisbasierter und populationsbezogener Daten der Untersuchung patientenrelevanter Endpunkte sowie der Entwicklung von Versorgungsmodellen und Präventionskonzepten für Menschen mit diabetischen Fußproblemen widmen.
Cerebral microhaemorrhage count is related to processing speed, but not level of symptom reporting, independently of age, psychological status and premorbid functioning, after first-ever mild traumatic brain injury
Authors: Anderson Jacqueline F.I. , Higson Lana , Wu Michelle H. , Seal Marc L. , Yang Joseph Yuan-Mou 
Published: June 2023

AbstractCerebral microhaemorrhage is a commonly identified neuropathological consequence of mild traumatic brain injury (mTBI) and can be identified in vivo using susceptibility weighted imaging (SWI). This study aimed to determine whether SWI-detected microhaemorrhages are more common in individuals after a single, first-ever, mTBI event relative to trauma controls (TC) and to investigate whether a linear relationship exists between microhaemorrhage numbers and cognition or symptom reporting in the post-acute period after injury, independently of age, psychological status and premorbid level of functioning. Microhaemorrhagic lesions were identified by expert clinical examination of SWI for 78 premorbidly healthy adult participants who were admitted to hospital after a traumatic injury and had suffered a first-ever mTBI (n = 47) or no head strike (n = 31). Participants underwent objective cognitive examination of processing speed, attention, memory, and executive function as well as self-reported post-concussion symptomatology. Bootstrapping analyses were used as data were not normally distributed. Analyses revealed that the mTBI group had significantly more microhaemorrhages than the TC group (Cohen’s d = 0.559). These lesions were only evident in 28% of individuals. The mTBI participants demonstrated a significant linear association between number of microhaemorrhages and processing speed, independently of age, psychological status, or premorbid level of functioning. This study shows that a single mTBI causes cerebral microhaemorrhages to occur in a minority of premorbidly healthy individuals. Greater microhaemorrhage count is independently associated with slower processing speed, but not symptom reporting, during the post-acute injury period.
Investigation into the operation of an autothermal two-section subbituminous coal fluidized bed gasifier
Authors: Abaimov Nikolay , Ryzhkov Alexander , Dubinin Alexey , Ding Lu , Tuponogov Vladimir , Alekseenko Sergey 
Published: June 2023

AbstractUsing a newly developed experimental setup, the features and advantages of an autothermal single-casing atmospheric subbituminous coal fluidized bed air-blown gasifier, combining a combustion and gasification section, and mixing the dispersed phase (inert material, char) and heat exchange between them through an annular transfer device, have been revealed. To increase the efficiency of the gasifier, an experimental-computational method was developed find the conditions for optimal operation, combining changing the annular flow’s geometry and regulating the primary air for gasification. A simple and reliable multizone thermodynamic calculation model makes it possible to predict the composition of char and syngas in the gasification section with acceptable accuracy. This method confirmed that a two-section fluidized bed gasifier can provide efficient gasification of solid fuels and is suitable for use in small-scale cogeneration plants. Syngas with a heating value of 3.6–4.5 MJ/m3 and CGE of 38.2%–42.3% was obtained in the experimental setup without optimizing the primary air flow rate. With optimization, the indicators increased to the heating value of syngas of 5.20–5.34 MJ/m3 and CGE of 42.5%–50.0%. With heat regeneration of 0.8, CGE increases to 70%.
Visualization facilitates uncertainty evaluation of multiple-point geostatistical stochastic simulation
Authors: Huang Qianhong , Chen Qiyu , Liu Gang , Cui Zhesi 
Published: June 2023

AbstractStochastic simulation is an essential method for modeling complex geological structures in geosciences. Evaluating the uncertainty of the realizations of stochastic simulations can better describe real phenomena. However, uncertainty evaluation of stochastic simulation methods remains a challenge due to the limited data from geological surveys and the uncertainty in reliability estimation with stochastic simulation models. In addition, understanding the sensitivity of the parameters in stochastic simulation models is invaluable when exploring the parameters with a higher influence on the uncertainty associated with predictions generated from stochastic simulation. To facilitate uncertainty evaluation in stochastic simulation methods, we use the circular treemap as an interactive workflow to explore prediction uncertainty in and the parameter sensitivity of multiple-point geostatistical (MPS) stochastic simulation methods. In this work, we present a novel visualization framework for assessing the uncertainty in MPS stochastic simulation methods and exploring the parameter sensitivity of the MPS methods. We present a new indicator to integrate multiple metrics that characterize geospatial features and visualize these metrics to assist domain experts in making decisions. Parallel coordinates-scatter matrix plots and multi-dimensional scaling (MDS) plots are used to analyze the parametric sensitivity of MPS stochastic simulation methods. The realizations and parameters of two MPS stochastic simulation methods are used to test the applicability of the proposed visualization workflow and the visualization methods. The results demonstrate that our workflow and the visualization methods can assist experts in finding the model with less uncertainty and improve the efficiency of parameter adjustment using different MPS stochastic simulation methods.
Trade-offs between indigenous forest and exotic production forest in New Zealand
Authors: Walsh Patrick J. , Soliman Tarek , Daigneault Adam 
Published: June 2023

AbstractWith its varied landscape of hills and mountains, New Zealand has an abundance of marginal land on its slopes. This land is currently used in a variety of enterprises, such as pasture and farmland. However, marginal land is typically associated with higher rates of erosion, shallow topsoil, expensive fencing, and other issues like livestock deaths from falls. There is currently interest in deploying these marginal lands to different uses to align with several environmental and production-related goals. This paper contributes to the discussion on marginal land by exploring three different scenarios related to afforestation in the Manawatu catchment area. To analyze these scenarios, we bring together several complex and spatially explicit data sets which are linked using economic modeling tools and benefits transfer methods. The combination of these tools and data sets allows us to produce several important quantitative and qualitative outputs. Where possible, quantitative predictions are monetized, allowing a benefit-cost analysis of the proposed scenarios.
Exploration-exploitation-based trajectory tracking of mobile robots using Gaussian processes and model predictive control
Authors: Eschmann Hannes , Ebel Henrik , Eberhard Peter 
Published: June 2023

AbstractMobile robots are a key component for the automation of many tasks that either require high precision or are deemed too hazardous for human personnel. One of the typical duties for mobile robots in the industrial sector is to perform trajectory tracking, which involves pursuing a specific path through both space and time. In this paper, an iterative learning-based procedure for highly accurate tracking is proposed. This contribution shows how data-based techniques, namely Gaussian process regression, can be used to tailor a motion model to a specific reoccurring reference. The procedure is capable of explorative behavior meaning that the robot automatically explores states around the prescribed trajectory, enriching the data set for learning and increasing the robustness and practical training accuracy. The trade-off between highly accurate tracking and exploration is done automatically by an optimization-based reference generator using a suitable cost function minimizing the posterior variance of the underlying Gaussian process model. While this study focuses on omnidirectional mobile robots, the scheme can be applied to a wide range of mobile robots. The effectiveness of this approach is validated in meaningful real-world experiments on a custom-built omnidirectional mobile robot where it is shown that explorative behavior can outperform purely exploitative approaches.
Secure from the World’s Contagions: Settlement House Summer Camping in the Progressive Era
Authors: Meier Dustin 
Published: June 2023

AbstractThroughout the Progressive Era, settlement houses in the urban Northeast and Midwest operated robust summer camp programs for the children of their neighborhoods. Each summer, campers enjoyed two weeks of hiking, swimming, nature study, and relaxation. This article argues that summer camps exemplified the environmental agenda of settlement-house workers during the Progressive Era. Unlike smoke abatement, sanitation reform, or playground construction, which addressed isolated components of the urban environment, camps allowed them to articulate a deeply ecological critique of the industrial city. Settlement-house workers constructed camp landscapes and daily programming in response to problems endemic to atmosphere, city streets, and immigrants’ homes, providing children with a total environmental change while meanwhile pursuing slower and more piecemeal reforms back in the city. Settlement house leaders and other Progressive Era reformers discerned an intimate connection between landscapes and morality, which summer camps allowed them to address since they could reform individual behavior in addition to combatting structural inequities. Summer camps demonstrate that settlement-house workers’ environmental philosophy permeated their reform agendas, influencing social work and recreation in addition to politics and public health.
E‐Field Effects on Day‐To‐Day Variations of Geomagnetic Mid‐Latitude Sporadic E Layers
Authors: Andoh Satoshi , Saito Akinori , Shinagawa Hiroyuki 
Published: June 2023

AbstractThis study investigates the effects of the electric fields (E‐fields) on day‐to‐day variations in geomagnetic mid‐latitude sporadic E layers (EsLs) using a numerical ionospheric model. It is widely accepted that geomagnetic mid‐latitude EsL dynamics depend largely on wind shear variations. In contrast, E‐field effects on geomagnetic mid‐latitude EsLs have not been investigated extensively and are still little known. Previous observations have reported that E‐fields change EsL heights by only several kilometers. However, no studies have investigated E‐field effects on day‐to‐day EsL variations. Recently, our numerical ionospheric model succeeded generally in reproducing day‐to‐day EsL variations driven by winds at geomagnetic mid‐latitudes. In this study, using the ionospheric model, we conducted EsL simulations including both E‐fields and winds, to elucidate how E‐fields affect day‐to‐day EsL variations at geomagnetic mid‐latitudes. It was found that zonal and meridional/vertical E‐fields change the vertical EsL dynamics above ∼110 km. Below ∼130 km, where most Es layers appear, vertical/meridional E‐fields are more effective for EsL dynamics than zonal E‐fields. During the day, E‐fields pump metal ions from the lower ionosphere to more than 110 km. Pumping facilitates the formation of daytime EsLs above ∼110 km. In the evening, E‐fields drive downward ion motion and increase the descending EsL density and occurrence. E‐fields affect day‐to‐day EsL variations at geomagnetic mid‐latitudes by altering background metal ion distribution and transport.
Variability and Remote Controls of the Warm‐Water Halo and Taylor Cap at Maud Rise
Authors: Gülk Birte , Roquet Fabien , Naveira Garabato Alberto C. , Narayanan Aditya , Rousset Clément , Madec Gurvan 
Published: June 2023

AbstractThe region of Maud Rise, a seamount in the Weddell Sea, is known for the occurrence of irregular polynya openings during the winter months. Hydrographic observations have shown the presence of a warmer water mass below the mixed layer along the seamount's flanks, commonly termed the warm‐water Halo, surrounding a colder region above the rise, the Taylor Cap. Here we use two observational data sets, an eddy‐permitting reanalysis product and regional high‐resolution simulations, to investigate the interannual variability of the Halo and Taylor Cap for the period 2007–2022. Observations include novel hydrographic profiles obtained in the Maud Rise area in January 2022, during the first SO‐CHIC cruise. It is demonstrated that the temperature of deep waters around Maud Rise exhibits strong interannual variability within the Halo and Taylor Cap, occasionally to such an extent that the two features become indistinguishable. A warming of deep waters by as much as 0.8°C is observed in the Taylor Cap during the years preceding the opening of a polynya in 2016 and 2017, starting in 2011. By analyzing regional simulations, we show that most of the observed variability in the Halo is forced remotely by advection of deep waters from the Weddell Gyre into the region surrounding Maud Rise. Our highest‐resolution simulation indicates that mesoscale eddies subsequently transfer the properties of the Halo's deep waters onto the Taylor Cap. The eddies responsible for such transfer originate in an abrupt retroflection along the inner flank of the Halo.
Subtropical Gyre Nutrient Cycling in the Upper Ocean: Insights From a Nutrient‐Ratio Budget Method
Authors: Xiang Yang , Quay Paul D. , Sonnerup Rolf E. , Fassbender Andrea J. 
Published: June 2023

AbstractWe use a nutrient‐ratio budget method to investigate the relative importance of different nutrient source and sink terms at time‐series Station ALOHA and Bermuda Atlantic Time‐series Study (BATS) in the North Pacific and North Atlantic subtropical gyres, respectively. At mean state conditions over annual and multi‐year time scales, vertical phosphate () supply from the subsurface accounts for ∼60% of the total phosphorus supply at both sites. Dissolved organic matter transport and zooplankton excretion are more important phosphorous export pathways than sinking particles at Station ALOHA and BATS. The nutrient‐ratio budget approach provides quantitative, observation‐based constraints on nutrient sources and sinks in the surface ocean, which helps improve our understanding of the biological carbon pump in oligotrophic oceans.
Photoferrotrophic Bacteria Initiated Plate Tectonics in the Neoarchean
Authors: Zhang Shengxing , Li Yiliang , Leng Wei , Gurnis Michael 
Published: June 2023

AbstractPlate tectonics distinguishes Earth from the other terrestrial planets but its initiation mechanism and onset time are debated. We propose plate tectonics was initiated by the deposition of magnetite‐rich banded iron formations (BIFs) through biogeochemical iron cycling in Neoarchean oceans. In the photic zone of proto‐continental margins, photoferrotrophic bacteria efficiently oxidized the dissolved Fe(II) and induced massive precipitation of ferric oxyhydroxide, which would rapidly react with Fe(II)‐rich hydrothermal fluids from coeval vigorous volcanism in Neoarchean oceans to produce magnetite‐rich BIFs. Mechanical models demonstrate that the localization of high‐density BIF deposition near proto‐continents induces collapse of the lithosphere and can initiate the earliest subduction. The peak deposition of BIFs in 2.75–2.40 Ga provides a time constraint on the inception of plate tectonics.
Health literacy of people with spinal cord injury: a systematic review
Authors: Silva Francine A. R. , Barbosa Maria A. , Prudente Cejane O. M. , Morais Letícia A. , Moraes Katarinne L. , Vila Vanessa S. C. , Porto Celmo C. 
Published: June 2023

Abstract
Study design
Systematic review.

Objective
To systematically review the evidence on health literacy (HL) of people diagnosed with spinal cord injury (SCI).

Methods
PubMed, Cochrane Library, Web of Science and Embase databases were used to identify studies published from 1974 to 2021. Two reviewers independently carried out the study selection process and assessed the methodological quality of the studies. The risk of bias in the studies was classified according to the Joanna Briggs Institute (JBI).

Results
In total, 1398 studies were identified from the initial search, and 11 were selected for reading thoroughly. After screening, five studies were included. All had a cross-sectional design, and most scientific production was from the United States. In the studies, people with SCI received assistance in rehabilitation services. The results were heterogeneous compared to the HL: reasonable HL; suitable HL; Inadequate HL. Better HL was identified in individuals from the white population compared to the black population with SCI.

Conclusion
Studies on HL in the SCI population are limited. Guidance and personalized education provided in rehabilitation programs seem to have an influence on HL levels in this population. More research is needed to broaden the understanding of HL in the rehabilitation process of people diagnosed with SCI.
Computational model for lipid binding regions in phospholipase (Ves a 1) from Vespa venom
Authors: Pattaranggoon Nawanwat C. , Daduang Sakda , Rungrotmongkol Thanyada , Teajaroen Withan , Tipmanee Varomyalin , Hannongbua Supot 
Published: June 2023

AbstractThe Thai banded tiger wasp (Vespa affinis) is a dangerous vespid species found in Southeast Asia, and its stings often result in fatalities due to the presence of lethal phospholipase A$$_{1}$$

1

, known as Vespapase or Ves a 1. Developing anti-venoms for Ves a 1 using chemical drugs, such as chemical drug guide, remains a challenging task. In this study, we screened 2056 drugs against the opening conformation of the venom using the ZINC 15 and e-Drug 3D databases. The binding free energy of the top five drug candidates complexed with Ves a 1 was calculated using 300-ns-MD trajectories. Our results revealed that voxilaprevir had a higher binding free energy at the catalytic sites than other drug candidates. Furthermore, the MD simulation results indicated that voxilaprevir formed stable conformations within the catalytic pocket. Consequently, voxilaprevir could act as a potent inhibitor, opening up avenues for the development of more effective anti-venom therapeutics for Ves a 1.