bluuebunny/crossref_metadata_2025_split huggingface dataset:
Number of Stairs at Home Does Not Influence Discharge Disposition following Elective Total Hip Arthroplasty
Authors: Murtaugh Taylor , Held Michael B , Levitsky Matthew M , Iorio Richard , Neuwirth Alexander L , Geller Jeffrey A , Cooper H. John , Shah Roshan P 
Published: August 2023

Background Pragmatic challenges of the patient’s home environment, specifically the number of stairs (NOS) required to enter or navigate a patient’s home may influence discharge destination (DD) and length of stay (LOS) following primary Total Hip Arthroplasty (THA). Questions/purposes This study investigates whether the NOS at home predicts discharge to a post-acute-care-facility (PACF) following THA. Methods 548 consecutive THA patients at a single urban arthroplasty center between 2011-2014 were reviewed. Patient factors including age, sex, BMI, length of stay, operative time, Anesthesia Score Assessment (ASA), the Risk-Assessment-and-Prediction-Tool (RAPT) and NOS stairs were analyzed. Logistic regression was performed to identify predictors for disposition to PACF. Groups were cohorted by number of stairs, and incidence of PACF discharge was determined. Results 238 (43.4%) patients were discharged to PACF. The NOS at home had no impact on discharge to PACF (OR 1.02, 95% CI .993-1.04, p=0.209). Older age (OR 1.09, 95% 1.07-1.10, p<0.0001), LOS (OR 1.23, 95% 1.08-1.39, p=0.001), higher ASA (OR 1.74, 95% 1.19-2.53, p=0.004), and lower RAPT score (OR 0.0.865, 95% 0.781-0.958, p=0.005) were significant predictors for disposition to PACF (p<0.005). Female sex was protective in discharge to PACF (OR 0.391, 95% 0.260-0.587, p<0.0001). The incidence of PACF discharge was similar between groups of unavoidable stairs at home. Conclusion The NOS at home did not influence discharge destination following THA. This retrospective study helps discharge planning and in setting expectations for patients undergoing THA by supporting a home discharge in the setting of unavoidable stairs.
Surgical Repair and Augmentation of a Large Type-2 Re-tear of the Rotator Cuff with a Novel Biocomposite Scaffold: A Case Report
Authors: Mc Millan Sean , Ford Elizabeth , Sigman Scott 
Published: August 2023

Case A 55-year-old female presented with pain and weakness in her right shoulder after a new traumatic event occurred. She had undergone a rotator cuff repair to this right shoulder 4 months earlier with dermal strip augmentation secondary to poor tissue quality at the time of index surgery. For historical context, her contralateral shoulder had undergone a previous primary rotator cuff repair with xenograft, which failed, and was ultimately revised to a full thickness repair 2 years prior. A repeat MRI demonstrated a recurrent large type-II rotator cuff tear with grade 3 Goutallier fatty infiltration. A novel biocomposite scaffold (BioBrace™) was used to augment a revision double row bridge repair with margin convergence. MRI at three and eight months after surgery suggested functional remodeling and growth of new tissue. At 10 months, arthroscopy was performed to evaluate bicipital pain and arthroscopic images demonstrated full incorporation of the biocomposite scaffold within the underlying native tendon and an intact repair. The source of bicipital pain was unrelated to the implant and a biceps tenodesis was performed to resolve the pain. Clinical outcomes were assessed preoperatively and at 1 year postoperatively using the Visual Analog Scale (VAS), American Shoulder and Elbow Surgeons (ASES) Shoulder Score, and Single Assessment Numeric Evaluation (SANE). Conclusion The use of a novel biocomposite scaffold augmentation for revision rotator cuff repair demonstrated evidence of healing, incorporation, and remodeling at 10 months post-procedure. VAS, ASES, and SANE pre- and post-operative outcome scores were analyzed at 1 year demonstrating significant improvement across all metrics. This case report suggests the use of a novel biocomposite rotator cuff augment can provide a via option for revision rotator cuff repair.
Robotic Assisted Total Knee Arthroplasty in Arthrofibrosis or the Preoperatively Stiff Knee: A Case Report
Authors: Passano Brandon , Becker Jacob , Koenig Jan A. 
Published: August 2023

Total knee arthroplasty (TKA) for arthrofibrosis or preoperatively stiff knees can present a set of difficult problems that challenge both the patient and surgeon. Patients with limited preoperative range of motion (ROM) are inherently at risk for worse outcomes. Prior literature has demonstrated the utility of robotic-assisted TKA (raTKA) regarding gap balancing and coronal deformity, however it has not been previously described in context of the preoperatively stiff knee. Here, we report a case of a patient undergoing primary TKA for severe osteoarthritis with significant preoperative stiffness resulting in severely limited ROM of only 5 degrees. This was performed with the use of a navigated raTKA system in conjunction with dynamic predictive balancing technology. With this method, the knee was balanced through bony cuts without the need for extensive soft tissue releases. This patient had excellent improvement in ROM and KOOS Scores at 3-month follow up. This patient’s early post-operative results demonstrate the potential benefits of utilizing raTKA for preoperative stiff knees and may lay groundwork for future literature.
New reconstructive option in chronic distal biceps ruptures. A case report.
Authors: Tovar-Bazaga Miguel , Pérez-Cuesta Llaneras Maria , Badia Alejandro 
Published: August 2023

Introduction Distal biceps ruptures usually present as an acute injury. Difficulties in treatment happen when the presentation is delayed, becoming a real challenge. Description of the issue We present a case report of a young bodybuilder who suffered a distal biceps rupture with 35 days of treatment’s delay. Treatment A surgical distal biceps reconstruction was performed. Due to prolonged chronology, a surgical repair was not possible. An acellular dermal matrix was used as a graft in order to reconstruct the retracted and frayed tendon. Intraoperative and one year follow-up clinical photos are presented showing full range of motion. Discussion Chronic distal biceps rupture is a challenging issue. A sterile acellular dermal matrix, used with a meticulous surgical technique, has shown a strong reconstruction with promising functional outcomes.
Biomechanical Effect of Ankle Ligament Injury in AO Type 44B2.1 Lateral Malleolus Fractures After Lateral Plate Fixation: A Finite Element Analysis
Authors: Olçar Hacı Ali , Mutu Halil Burak , Özer Alaettin , Kuru Tolgahan , Aydın Davut , Korkmaz Murat 
Published: August 2023

Background: Distal fibula fractures at the ankle level are common and are usually accompanied by ligament injuries. This study aims to evaluate the effects of ankle ligament ruptures on ankle joints, fracture instability, and plate stress after distal fibula fracture fixed with a plate created by finite element analysis modeling and loading applied to ligament rupture models that may accompany this fracture.
Methods: A finite element model consisting of three-dimensional fibula, tibia, foot bones, and ankle ligaments was designed to investigate the effects of ligament injuries accompanying plate-detected AO type 44B2.1 fractures on fracture detection, fixation material, and ankle joints. Then, the results were evaluated by modeling ligament rupture in six different ways.
Results: In the modeling where the deltoid and talofibular ligaments are broken together, instability is highest in the ankle (2.31 mm) and fracture line (0.15 mm). The rupture of the anterior and posterior tibiofibular ligaments associated with syndesmosis caused less instability in the fracture and ankle than the single-ligament rupture models of both the deltoid and talofibular ligaments.
Conclusions: In the finite element modeling of AO type 44B2.1 fractures detected with plate, the importance and potential effects of often-overlooked ankle ligament injuries are pointed out. Note that when treating ankle injuries, the ankle should be treated as a whole, with both bone and soft tissue. In some cases, the fracture may represent the visible tip of the iceberg.
Analysis of Salicylic Acid in Tobacco Leaves Using Capillary Zone Electrophoresis with UV Detection
Authors: Chen Wei-Ting , Wang Chiung-I , Fu Shih-Feng , Lin Yang-Wei 
Published: August 2023

AbstractA simple and inexpensive capillary zone electrophoresis (CZE) with UV detection method was used to determine salicylic acid (SA) and six structural analogs (benzoic acid, 3-hydroxybenzoic acid, 4-hydroxybenzoic acid, acetylsalicylic acid, methyl salicylate, and jasmonic acid). All of the compounds were successfully separated within a migration period of 6 min, with a high number of theoretical plates (>37,000, calculated using the width at the base of the SA peak), in 20.0 mmol L-1 Na2HPO4/H3BO3 buffer (pH 9.0) containing 2.0% methanol and 2.0% acetonitrile. The regression line for SA was linear over the range 0.5–200 µmol L-1. Both the intra- and inter-day precisions of the migration time (relative standard deviations, RSDs, 0.6% and 4.7%, respectively) and peak area (RSDs 0.9% and 7.3%, respectively) were acceptable. The proposed method was used to determine the SA concentrations in tobacco leaves ( Nicotiana tabacum L.) from the Xanthi-nc ( NN genotype) and the Nt-NahG mutant strains that had been irradiated with UV (254 nm) for 20 min and the ones that had not been irradiated. Rapid separation (<6 min), good reproducibilities (RSDs < 11.9%), and good recoveries (94.7–118%) were obtained in the tobacco leaf analyses.
Effect of Surfactant Tail Structure on Phase Behavior of Branched and Linear Alkylbenzene Sulfonate in Water and Oil Ternary Systems
Authors: Al Bawab Abeer , Bozeya Ayat , Odeh Fadwa 
Published: August 2023

AbstractSystematic investigations into the phase behavior of a ternary system of linear alkyl benzene sulfonate (LAS) or branched alkyl benzene sulfonate (BAS) in oil (corn or olive oil) and water were carried out. The study showed that there is a relationship between the surfactants’ chemical structure, aggregation properties, and the formation of micelles. The aggregation properties were dramatically affected by small structural variations of the hydrophobic group at constant carbon number. Micelles formation was found to be correlated with the extent of chain branching by affecting oil-water interfacial tension, where the branched alkyl tail has significantly more ability to form micelles than the linear one. It was found possible to distinguish between LAS and BAS based on their phase behavior.
Characterization of Phytic acid in Tempered Canned Red kidney beans (Phaseolus vulgaris) using Raman Spectroscopy
Authors: Kassama Lamin S. , Sanusi Temitope O. 
Published: August 2023

AbstractRapid and non-invasive analytical method for quality control is a priority for the food industry, hence the objective of this study is to use Raman spectroscopy (RS) to identify phytic acid in RKB. Phytic Acid was extracted from treated ground dry RKB, while standard concentration of PA was prepared from a PA solution 50% w/w. Extracted samples and standard solutions were analyzed using the RS. The laser light beams focused on the PA samples generated molecular bond vibrations which resulted to inelastic scattering of photons in the light beam. The result showed that P-O-C, and P=O which are bonds identified with PA emitted light intensities at wavelength 858.13, and 1198.04 nm, respectively. Correlation (0.93) was established between results obtained for the standard RAMAN spectroscopy method and UV spectrophotometric method. Canned BL treatments showed increased concentration with blanched samples with lowest concentration (0.1175 g/mL) for P-O-C. Thus, the correlation established is indicative that the RS has potential applications in the food industry.
Adaptive Fuzzy Sliding Mode Controller for Attitude Coordinated Control in Spacecraft Formation
Authors: Xin Wen , Shasha Zhu , Xingwang Zhang 
Published: August 2023

AbstractThe attitude coordinated control problem of a spacecraft formation in leader-follower approach is considered in this paper. An adaptive fuzzy sliding mode control scheme is designed to achieve tracking and synchronization in spacecraft formation in the presence of model uncertainties and external disturbances. The proposed control law consists of two parts: equivalent control and switching control. In order to attenuate high-frequency chattering caused by the switching control, the adaptive fuzzy control is utilized to approximate the sign function of the switching control. Moreover, fuzzy rules are employed to smooth the switching control based on the sliding surface. Lyapunov theory is applied to proof the stability of the closed-loop system. Finally, simulation results and comparative analysis are carried out to demonstrate the effectiveness of the proposed method.
Utilization and Spending With Preventive Drug Lists for Asthma Medications in High-Deductible Health Plans
Authors: Sinaiko Anna D. , Ross-Degnan Dennis , Wharam J. Frank , LeCates Robert F. , Wu Ann Chen , Zhang Fang , Galbraith Alison A. 
Published: August 2023

ImportanceHigh-deductible health plans with health savings accounts (HDHP-HSAs) incentivize patients to use less health care, including necessary care. Preventive drug lists (PDLs) exempt high-value medications from the deductible, reducing out-of-pocket cost sharing; the associations of PDLs with health outcomes among patients with asthma is unknown.ObjectiveTo evaluate the associations of a PDL for asthma medications on utilization, adverse outcomes, and patient spending for HDHP-HSA enrollees with asthma.Design, Setting, and ParticipantsThis case-control study used matched groups of patients with asthma before and after an insurance design change using a national commercial health insurance claims data set from 2004-2017. Participants included patients aged 4 to 64 years enrolled for 1 year in an HDHP-HSA without a PDL in which asthma medications were subject to the deductible who then transitioned to an HDHP-HSA with a PDL that included asthma medications; these patients were compared with a matched weighted sample of patients with 2 years of continuous enrollment in an HDHP-HSA without a PDL. Models controlled for patient demographics and asthma severity and were stratified by neighborhood income. Analyses were conducted from October 2020 to June 2023.ExposuresEmployer-mandated addition of a PDL that included asthma medications to an existing HDHP-HSA.Main Outcomes and MeasuresOutcomes of interest were utilization of asthma medications on the PDL (controllers and albuterol), asthma exacerbations (oral steroid bursts and asthma-related emergency department use), and out-of-pocket spending (all and asthma-specific).ResultsA total of 12 174 participants (mean [SD] age, 36.9 [16.9] years; 6848 [56.25%] female) were included in analyses. Compared with no PDL, PDLs were associated with increased rates of 30-day fills per enrollee for any controller medication (change, 0.10 [95% CI, 0.03 to 0.17] fills per enrollee; 12.9% increase) and for combination inhaled corticosteroid long-acting β2-agonist (ICS-LABA) medications (change, 0.06 [95% CI, 0.01 to 0.10] fills per enrollee; 25.4% increase), and increased proportion of days covered with ICS-LABA (6.0% [0.7% to 11.3%] of days; 15.6% increase). Gaining a PDL was associated with decreased out-of-pocket spending on asthma care (change, −$34 [95% CI, −$47 to −$21] per enrollee; 28.4% difference), but there was no significant change in asthma exacerbations and no difference in results by income.Conclusions and RelevanceIn this case-control study, reducing cost-sharing for asthma medications through a PDL was associated with increased adherence to controller medications, notably ICS-LABA medications used by patients with more severe asthma, but was not associated with improved clinical outcomes. These findings suggest that PDLs are a potential strategy to improve access and affordability of asthma care for patients in HDHP-HSAs.
Ultra‐Thin Ceramic Substrates for Improved Heat sinking for MicroLEDs
Authors: McGinn Christine K. , Kumar Vikrant , Noga Megan , Lamport Zachary , Kymissis Ioannis 
Published: August 2023

AbstractMicro light emitting diodes (MicroLEDs) provide unrivaled luminance and operating lifetime, which has led to significant activity using devices for display and non‐display applications. The small size and high power density of microLEDs, however, causes increased adverse heating effects that can limit performance. A new generation of electrically insulating high thermal conductivity materials, such as alumina, is proposed to mitigate these thermal effects when used as a substrate as an alternative to glass. This strategy can then be used as a method of passive heat sinking to improve the overall performance of the microLED. In this work, a newly available material, an 80 micron thick alumina ceramic substrate, is shown to yield a 30 % improvement on average in the maximum current drive over a glass substrate.
High‐Performance Neutral Zinc‐Air Batteries Based on Hybrid Zinc/Carbon Nanotube Fiber Anodes
Authors: Chen Hao , Li Luhe , Wang Lie , Li Fangyan , Wang Jiacheng , Jiao Yiding , Zhang Ye 
Published: August 2023

AbstractNeutral zinc‐air batteries are considered potential wearable energy storage devices due to their high theoretical energy density, superior safety, and low cost. However, the current performance of neutral zinc‐air batteries is severely influenced by the zinc anodes. The pure zinc anode can be comminuted during charge and discharge cycles due to its unstable electrode structure, resulting in the failure of electrical contact. As a result, the battery exhibits low capacity and short cycle life. In addition, the pure zinc anodes show slow reaction kinetics in neutral electrolytes, which causes the battery to perform low power density and poor energy efficiency. Besides, pure zinc anodes own high bending stiffness, which cannot meet the demands for powering flexible electronics. Herein, a new kind of hybrid zinc/carbon nanotube fiber anode with a stable electrode structure, high reaction activity, as well as high flexibility is proposed to produce high‐performance neutral zinc‐air batteries. The fabricated fiber battery showed a high specific capacity and maximum power density of 645.3 mAh g−1 and 615.8 mW g−1, respectively. Furthermore, a high energy efficiency of 71% is achieved, the highest among the reported neutral zinc‐air batteries. The entire fiber battery is highly flexible, highlighting its potential for wearable energy storage applications.
Derivatives Based on Cyclodextrin Structure for Adsorption of Heavy Metal Ions and Organic Pollutants in Wastewater
Authors: Shang Wanchuan , Wang Xueyin , Zhang Xiaoning , Zhang Caidi , Huang Xueli , Li Kaihong 
Published: August 2023

AbstractThis study provides a solution for the treatment of heavy metal ions as well as common organic pollutants in water by adsorption, which contributes to the achievement of sustainable development goals. In this work, a new adsorption material, β‐cyclodextrin‐acrylic acid‐acrylamide (CD‐AA‐AM‐MBA), is synthesized. The structure of the materials is characterized and analyzed using fourier transform infrared spectroscopy (FT‐IR), Xray diffraction spectroscopy(XRD), scanning electron microscopy(SEM) and thermogravimetric analysis(TGA). The effects of initial ion concentration, contact time, and different pH values on the adsorption performance are studied. Under the optimized conditions, the adsorption capacity in CD‐AA‐AM‐MBA of Cu2+, Pb2+, Cd2+, Methylene Blue(MB), Methyl Orange(MO), phenol, m‐cresol and p‐cresol are 58.66, 326, 48.5, 58.27, 51.34, 6.63, 3.7 and 5.91 mg g−1.
Local and global gas–liquid mass transfer in a micro‐packed bed reactor utilizing a noninvasive colorimetric technique
Authors: Liu Wei , Xie Bingqi , Luo Jing , Zhang Chenghao , Zhang Jisong 
Published: August 2023

AbstractMicro‐packed bed reactor (μPBR) presents great potential in the field of multiphase reactions due to the features of safety and high efficiency. However, the deeper cognition of mass transfer needs to be taken into consideration that is the foundation of reactor design. In this work, local and global gas–liquid mass transfer in the μPBR were studied utilizing a noninvasive colorimetric technique. In reactor level, the qualitative and quantitative comparisons were conducted; in particle level, liquid flow and mass transfer textures were assessed for the first time. The diversities of local mass transfer characteristics from temporal and spatial dimensions were obtained, and the heterogeneity of local and global mass transfer was revealed. The predicted correlations of in μPBR with churn flow and pseudo‐static flow were established with deviations generally within ±18%. This study contributes to improve the understanding of mass transfer and points out the process intensification direction of μPBR.
AT(N) biomarker profiles and Alzheimer's disease symptomology in Down syndrome
Authors: Hartley Sigan L. , Handen Benjamin , Tudorascu Dana , Lee Laisze , Cohen Annie , Schworer Emily K. , Peven Jamie C. , Zammit Matthew , Klunk William , Laymon Charles , Minhas Davneet , Luo Weiquan , Zaman Shahid , Ances Beau , Preboske Gregory , Christian Bradley T. ,   the Alzheimer Biomarker Consortium – Down Syndrome
Published: August 2023

AbstractINTRODUCTIONDown syndrome (DS) is a genetic cause of early‐onset Alzheimer's disease (AD). The National Institute on Aging–Alzheimer's Association AT(N) Research Framework is a staging model for AD biomarkers but has not been assessed in DS.METHODData are from the Alzheimer's Biomarker Consortium–Down Syndrome. Positron emission tomography (PET) amyloid beta (Aβ; 15 mCi of [11C]Pittsburgh compound B) and tau (10 mCi of [18F]AV‐1451) were used to classify amyloid (A) –/+ and tau (T) +/–. Hippocampal volume classified neurodegeneration (N) –/+. The modified Cued Recall Test assessed episodic memory.RESULTSAnalyses included 162 adults with DS (aged M = 38.84 years, standard deviation = 8.41). Overall, 69.8% of participants were classified as A–/T–/(N)–, 11.1% were A+/T–/(N)–, 5.6% were A+/T+/(N)–, and 9.3% were A+/T+/(N)+. Participants deemed cognitively stable were most likely to be A–T–(N)– and A+T–(N)–. Tau PET (T+) most closely aligning with memory impairment and AD clinical status.DISCUSSIONFindings add to understanding of AT(N) biomarker profiles in DS.Highlights
Overall, 69.8% of adults with Down syndrome (DS) aged 25 to 61 years were classified as amyloid (A)–/tau (T)–/neurodegeneration (N)–, 11.1% were A+/T–/(N)–, 5.6% were A+/T+/(N)–, and 9.3% were A+/T+/(N)+.
The AT(N) profiles were associated with clinical Alzheimer's disease (AD) status and with memory performance, with the presence of T+ aligned with AD clinical symptomology.
Findings inform models for predicting the transition to the prodromal stage of AD in DS.
Rhodium‐Catalyzed Asymmetric Arylation‐Induced Glycolate Aldol Additions of Silyl Glyoxylates
Authors: Turman Nolan C. , Smith Kendrick L. , Crawford Evan T. , Robins Jacob G. , Weber Kathryn M. , Liu Shubin , Johnson Jeffrey S. 
Published: August 2023

Abstract(Diene)Rh(I) complexes catalyze the stereoselective three‐component coupling of silyl glyoxylates, arylboronic acids, and aldehydes to give glycolate aldol products. The participation of Rh‐alkoxides in the requisite Brook rearrangement was established through two component Rh‐catalyzed couplings of silyl glyoxylates with ArB(OH)2 to give silyl‐protected mandelate derivatives. The intermediacy of a chiral Rh‐enolate was inferred through enantioselective protonation using a chiral Rh‐catalyst. Diastereoselective three‐component couplings with aldehydes as terminating electrophiles to give racemic products were best achieved with a bulky aryl ester on the silyl glyoxylate reagent. Optimal enantioselective couplings were carried out with the tert‐butyl ester variant using an anisole‐derived enantiopure tricyclo[3.2.2.02,4]nonadiene ligand.