bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of Bismuth Trioxide Nanoparticles and Evaluating Binding Affinity with Proteins
Authors: Singh Usha , Deotale Anjali J. , Mahns David A. , Hennessy Annemarie , George Laurel , Fanna Daniel J. , Wuhrer Richard , Daswani Ujla , Malladi Chandra S. 
Published: September 2023

AbstractProtein‐nanoparticle conjugation, or protein‐corona, is important for nanomedicine, nano diagnostic, and nano therapy applications. α‐Bismuth oxide nanoparticles (α‐Bi2O3 NPs) were prepared from bismuth nitrate powder using the sol‐gel method and characterized using various techniques, including Energy Dispersive X‐Ray Spectroscopy (EDS), X‐ray Diffraction (XRD), Raman spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), UV‐VIS‐NIR Spectroscopy, and Brunauer‐Emmett‐Teller (BET). X‐ray diffraction studies revealed that NPs are in the alpha phase with a monoclinic structure. The energy band gap, average surface area and crystallite size are 2.81 eV, 2.42 m2, and 15–106 nm, respectively. Transmission electron microscopy revealed particle size is 32.21 nm, with a d‐spacing of 2.529 Å. The surface‐to‐volume ratio is calculated and found to be 2.553×106 m−1. For the first time, a direct protein interaction with NPs was examined with standard proteins such as bovine serum albumin (BSA), carbonic anhydrase, phosphorylase b, and total human serum proteins and analyzed using mass spectroscopy. Proteomic analysis showed that proteins such as BSA, phosphorylase b, and carbonic anhydrase exhibited a strong affinity with Bi2O3 NPs. However, it was found that there was less or no association between Annexin A6, human serum albumin, Zinc finger protein, and Bestrophin‐2 with Bi2O3 NPs.
An Interhalogen‐Based Binary Redox Couple for the Efficiency Enhancement of Type‐II Dye‐Sensitized Solar Cells
Authors: Rahman Md. Mahbubur , Kwaku Asiam Francis , Chandra Deb Nath Narayan , Lee Jae‐Joon 
Published: September 2023

AbstractIn this work, the photovoltaic (PV) performance of dye‐sensitized solar cells (DSSCs), sensitized with salicylic acid (SA) and indole‐3‐acetic (IAA) and mediated by iodide (I−)/tri‐iodide (I3−), binary‐redox system (I−, Br−)/(I3−, I2Br−), and bromide (Br−)/tri‐bromide (Br3−), were investigated. The (I−, Br−)/(I3−, I2Br−) redox electrolyte induced the highest recombination resistance at the TiO2/dye/electrolyte interface for both SA and IAA‐sensitized DSSCs. Concurrently, additive‐free binary electrolyte‐based cells showed enhanced dye regeneration capability and decreased rate of back reaction compared to the cells prepared with additive‐free I−/I3− and Br−/Br3− electrolytes. Energy band alignment of SA and IAA and the optical analyses revealed the direct one‐step electron injection into the conduction band of TiO2 upon photoexcitation. Further, additive‐containing electrolytes showed decreased PV performance compared to the additive‐free electrolytes in both molecules sensitized DSSCs, conceivably due to the increased rate of back reaction with decreased charge collection efficiency. Thus, a maximum power conversion efficiency (PCE) of 0.57 % was attained for SA‐sensitized DSSCs based on additive‐free binary redox mediator, while the PCE values for additive‐free I−/I3− and Br−/Br3− electrolytes‐based identical cells were 0.19 and 0.54 %, respectively. This research suggests that the binary redox couple is a potential candidate for the PCE improvement of type‐II DSSCs.
Titanium Tetrachloride‐Based Ionic Liquids Immobilized on Mesoporous Fe‐MCM‐41 for the Heterogeneous Cooperative Synthesis of Dihydroquinazolinones
Authors: Hu Yu Lin , Rong Qi , Chen Chen , Liang Chen Hong 
Published: September 2023

AbstractIn this study, we report a successful strategy for the generation of a type of multifunctional heterogeneous supported ionic liquids catalysts. The synthesized supported ionic liquids (Fe‐MCM‐41/IL) were used in the catalytic cyclocondensation of 2‐aminobenzamide and various ketones and aldehydes towards the efficient synthesis of the dihydroquinazolinones under green conditions. The influence of the different catalysts and reaction parameters on the catalytic behaviors were sufficiently investigated. The supported catalyst (2)Fe‐MCM‐41/IL(0.6) showed the optimal catalytic efficiency. A hot filtration experiment revealed that the reaction proceeded in a heterogeneous pathway. The catalytic activity of (2)Fe‐MCM‐41/IL(0.6) could be maintained efficiently after recycling up to five consecutive runs under the optimized reaction conditions. Merits of this meticulously designed protocol are the use of novel supported catalyst, easy work‐up process, feasibility and sustainability, indicating its potential industrial application prospect.
Synthesis of a Water‐Soluble Pd‐Based Catalyst with a Thymine‐Modified β‐Cyclodextrin Ligand for Suzuki Coupling Reactions
Authors: Li Rui , Li Mengting , Jiao Caihong , Liu Junhui , Song Yakun , Guo Xuming 
Published: September 2023

AbstractHerein, the synthesis and crystal structure identification of thymine‐modified β‐cyclodextrin (mono‐(6‐Thymine‐6‐deoxy)‐β‐CD, Thy‐CD) are reported. The catalyst system (Pd@Thy‐CD) was prepared by using the thymine‐modified β‐cyclodextrin as ligand and palladium acetate (Pd(OAc)2) as palladium source. The as‐obtained Pd@Thy‐CD catalyst was characterized by NMR, IR, SEM, and XPS analysis. The catalyst can efficiently catalyze the aqueous phase Suzuki coupling reaction in situ. Under mild reaction conditions, the catalyst system provides excellent yields for the Suzuki coupling reaction of aryl halides, including with aryl chlorides and aryl boronic acids in water. The major advantages of this technique are the ease of preparation of the palladium catalyst, the aqueous phase coupling reaction, the broad functional group tolerance, and the easy recyclability.
Ethanol as a ‘Catalyst’ for Effective Phase Transfer and Self‐Assembly of Gold Nanorods
Authors: Zhang Min , Deng Tian‐Song , Cheng Zhiqun 
Published: September 2023

AbstractTransferring gold nanorods (GNRs) from an aqueous solution to a non‐polar solvent enhances self‐assembly, promotes biocompatibility, and boosts surface‐enhanced Raman scattering (SERS). However, the strong attachment ability of toxic hexadecyltrimethylammonium bromide (CTAB) to GNRs presents a significant challenge in the fall of CTAB and combining with other substances for self‐assembly and SERS applications. We propose a solution that employs ethanol as a ‘catalyst’ to lower the critical micelle concentration (CMC) of CTAB and efficiently combine it with the organosilanes formed by the hydrolysis of mercaptopropyltrimethoxysilane (MPS) and octadecyltrimethoxysilane (ODS). The samples were characterized by UV‐vis‐NIR spectroscopy, transmission electron microscopy (TEM), and energy disperse spectroscopy (EDS) mapping. A detailed interpretation of the phase transfer processes was provided. The modified particles were effectively dispersed in toluene and formed thin films at the air‐water interface through self‐assembly, which was confirmed by scanning electron microscopy (SEM) and optical microscopy. These films can serve as a platform for SERS.
A Sensitive Electrochemical Sensor Based on Hollow Spindle Ferric Oxide for the Determination of Hydrogen Sulfide
Authors: Lei Cang , Song Wenyu , Wei Yuantao , He Xiaoping , Zhang Lu , Yang Yuxiao , Xiao Chunhui 
Published: September 2023

AbstractA one‐step hydrothermal synthesis method was used to synthesize ferric oxide nanoparticles with unique hollow spindle microstructure, which were mixed with conductive carbon black (CCB) to construct an electrochemical sensor to realize the highly sensitive detection of trace hydrogen sulfide (H2S) in biological samples. Our findings suggested that hollow spindle ferric oxide (Hs‐Fe2O3) held good electrocatalytic activity toward H2S, which mainly depended on the coupling effect of Fe (III)/Fe (II) significantly reduced the overpotential of electro‐oxidation reaction of H2S. Importantly, the unique structure of the hollow spindle provided more catalytic active sites and more efficient mass transfer process, which effectively improved the detection performance. The proposed sensor had good sensing performances, with excellent sensitivity (2.4 times of commercial Fe2O3/CCB), low detection limit (1.86 μM), wide linear range (7.6~152 μM) and favorable selectivity. Furthermore, quantitative detection of H2S was achieved in fetal bovine serum samples, which confirmed that the sensor could become a promising strategy for detecting H2S in the pathological study of related diseases.
Synthesis, Characterization, Photophysical, Lifetime and NLO Studies of Chromenes
Authors: Palapetta Surya Cholayil , Kaviyarasan R. , Harichandran G. 
Published: September 2023

Abstract2‐Aminobenzochromenes and dihydropyranchromenes represent a unique class of biologically active compounds. We concentrate on the synthesis of biologically active compounds of chromenes using an environmentally friendly, heterogeneous green Amberlite IRA 400‐Cl resin catalyst. These chromene‐structured compounds enable them to be used as fluorescent sensors. The selected chromenes have been used as metal ion sensors to study their photophysical characteristics.
Study on the Morphological Mechanism of MoS2 Growth by NaCl‐Assisted Chemical Vapor Deposition
Authors: Wu Jinchao , Zhang Yandong , Jia Zhiyuan , Ma Zhongge , Song Jinhui 
Published: September 2023

AbstractMonolayer MoS2 is a two‐dimensional transition‐metal dichalcogenide (TMD), and its atomic‐level thickness makes it an appealing research target in beyond‐silicon devices. Future practical uses are intimately related to controllable synthesis of materials at present, and salt‐assisted chemical vapor deposition (SA‐CVD) offers a promising way. However, the specific growth mechanism of alkali metal salts on MoS2 crystal development and their influence on optoelectronic characteristics of the as‐grown MoS2 crystals is not fully identified. Here, based on large amount experiments, we present a vapor‐liquid‐solid (VLS) edge‐adsorbed growth model for synthesizing MoS2 nanoflakes, emphasizing the edge‐adsorbed phenomena of the alkali metal element Na in regulating MoS2 crystal shape. Through controlling flow rate of carrier gas, the MoS2 defective morphology can be effectively suppressed. This study contributes to a better understanding of the role of alkali metal halide salts in TMD development by providing experimental and theoretical evidence, which is critical for synthesizing high quality TMD by alkali metal halide salts catalyst.
Total and Diverted Total Synthesis of Pyrrolo‐Quinazolinone Alkaloids and Their Analogues
Authors: Rasapalli Sivappa , Huang Yanchang , Sammeta Vamshikrishna Reddy , Alshehry Reem , Anver Fazmina , Shivasankar Krishnamoorthy , Chavan Subash P. 
Published: September 2023

AbstractA short and expeditious total and diverted total synthesis of luotonin, vasicinone, and their analogues has been achieved from the key tricyclic quinazolinone intermediate which was accessed from simple substituted anthranilamide obtained from the coupling of β‐alanate with isatoic anhydride followed by Dieckmann condensation chemistry of the resulting diester. The tricyclic ketone exhibited interesting chemical properties, e. g. keto‐enol tautomerism. Friedlander condensation and Fischer‐Indolization were employed for further annulations to access polycyclic alkaloids and their analogues.
Fabrication of Superhydrophobic/Superoleophilic Kitchen Sponge for Removal and Separation of Oil from Water
Authors: He Meiru , Wang Huameng , Cheng Yuanyuan , Niu Qian , He Linlin , Liu Chunxue 
Published: September 2023

AbstractSuperhydrophobic/superoleophilic kitchen sponge has been fabricated successfully with water contact angle (WCA) about 153°, and organic solvent contact angle (CA) almost 0°. Scanning electron microscope (SEM), energy dispersive X‐ray spectra (EDX) and X‐ray photoelectron spectroscopy (XPS) were investigated respectively to characterize the surface morphology and chemical compositions. The superhydrophobic/superoleophilic kitchen sponge can easily remove organic solvent from water, such as chloroform, toluene, hexane, diethyl ether, ethyl acetate, peanut oil, and the adsorption capacity was about 28~59 times of the sponge's own weight. The recyclability of the superhydrophobic/superoleophilic sponge was very good even after 10 times. The absorbed oil can be removed by immersing into ethanol solution for 3 times and drying for 20 min at 50 °C. This superhydrophobic/superoleophilic sponge can also be used to separate various oil from water, such as chloroform and hexane, no matter heavy oil or light oil. Its excellent performance will offer important potential values for various applications and facilitate its industrialization.
One‐Pot Three‐Component Synthesis of 4‐Arylpyrimidin‐2‐amines Using Solid Calcium Carbide as a Surrogate of Gaseous Acetylene
Authors: Liao Haiyan , Li Zheng 
Published: September 2023

AbstractAn efficient method for the synthesis of 4‐arylpyrimidin‐2‐amines by the reactions of various aromatic aldehydes, guanidine and calcium carbide through one‐pot three‐component procedure is described. The salient features for this protocol are the use of an inexpensive and easy‐to‐handle solid calcium carbide instead of flammable and explosive gaseous acetylene as an alkyne source, cheap transition‐metal mediator, commercially available starting materials, wide substrate scope, satisfactory yield, and the simple workup procedure. The related reaction can also be extended to gram scale.
A Novel Bimetallic BaCu2O3 Catalyst for Csp2‐O Cross‐Coupling Reactions of Phenols with Arylhalide
Authors: Panda Subhalaxmi , Kumar Behera Pradyota , Behera Papita , Swain Amlan , Kumar Pradhan Amit , Rout Laxmidhar 
Published: September 2023

AbstractA new oxygen bridged [Cu‐O‐Ba] bimetallic catalyst is synthesized. The novel catalyst is used for Csp2‐O cross‐coupling reactions of phenols with haloarenes. Iodo‐, bromo‐, and unactivated chloro‐arenes could be coupled with aryl phenols efficiently in high yield. Moreover, functional groups were well tolerated using this protocol. The catalyst is Eco‐friendly, air stable, recyclable and efficient.
Catalyst‐ and Solvent‐Free Synthesis of Pentacyclic‐dione Derivatives from 4‐Hydroxythiocoumarin and Aldehyde Using Pseudo‐Three‐Component Reaction
Authors: Goswami Ujjwal Jyoti , Xalxo Anjela , Khan Abu Taleb 
Published: September 2023

AbstractThe synthesis of hitherto unreported pentacyclic‐dione derivatives having three heteroatoms in the ring is reported from 4‐hydroxythiocoumarins and aryl (hetero)/alkyl aldehydes under solvent‐ and catalyst‐free conditions through pseudo‐three‐component reaction. The reaction proceeds through Knoevenagel condensation of 4‐hydroxythiocoumarin with aldehyde followed by Michael addition with another molecule of 4‐hydroxythiocoumarin with the elimination of hydrogen sulfide to furnish the final product. The salient features of this protocol are mild reaction conditions, good yield, broad substrate scope, no need for catalyst or solvent or chromatographic separation, and high atom economy.
Recent Advances in the Anticancer Applications of Benzimidazole Derivatives
Authors: Mavvaji Mohammad , Akkoc Senem 
Published: September 2023

AbstractCancer, one of the most deadly diseases worldwide, is still a crucial challenge to human well‐being. Hence, the design and development of modern protocols to cure diverse kinds of cancer seem highly necessary. On the other hand, benzimidazole, as an essential pharmacophore, exhibits various biological and therapeutic potency. This compound is well‐known for its pharmaceutical features, including antifungal, antiviral, antibacterial, and anticancer activities. Therefore, benzimidazole derivatives have played an essential role due to their outstanding anticancer capability, apoptotic effect, and inhibitory potential. In recent decades, numerous anticancer drug types of research have been concentrated on finding new and practical strategies for employing benzimidazole‐based compounds. This review focuses on the latest advancements and methodologies for exploiting various benzimidazole‐bearing compounds for the treatment of varied sorts of cancer, considering the mechanism of their function against cancer cell lines.
N‐Heterocyclic Thione‐Coordinated Dinuclear Bismuth(III) Trihalides with a Rare Geometry
Authors: Nandeshwar Muneshwar , Mannarsamy Maruthupandi , Adinarayana Mannem , Prabusankar Ganesan 
Published: September 2023

AbstractTwo thione‐coordinated dinuclear bismuth(III) halides were isolated with a rare geometry and characterized using FT‐IR, NMR, and single‐crystal X‐ray diffraction techniques. The sterically less crowded N‐heterocyclic thione ligand gave bismuth(III) chloride‐thione complex in cis isomeric form, while the sterically more crowded N‐heterocyclic thione ligand gave dinuclear bismuth(III) bromide‐thione complex in facial isomeric form. Continuous shape measurement (CShM) revealed that the bismuth centres in cis‐bismuth(III) chloride‐thione complex adopts distorted octahedral geometry with the CShM values of 2.103, which is remarkably different compared to the facial‐dinuclear bismuth(III) bromide‐thione complex (1.071 and 0.391).
GABA–AT Inhibitors: Design, Synthesis, Pharmacological Characterization, Molecular Docking and ADMET Studies
Authors: Seyma Sevincli Zekiye , Bildirici Nurettin , Cetin Adnan , Bildirici Ishak 
Published: September 2023

Abstractγ‐aminobutyric acid (GABA) is the main neuroinhibitory transmitter and a non‐proteinogenic amino acid in the brain. When the brain concentration of GABA diminishes below a threshold level, it can cause excess neuronal excitation and lead to convulsions. γ‐Aminobutyric acid aminotransferase (GABA‐AT) is an enzyme that catalyzes the conversion of GABA to succinic semialdehyde in the GABA shunt pathway and responsible for breaking down GABA in the brain. By inhibiting GABA‐AT activity, it may be possible to increase the levels of GABA in the brain and reduce the likelihood of seizures. Herein, the synthesis and evaluation of α‐pyrazolo‐(aryl/alkyl)methyl‐ketone and pyrazolo[5,1‐a]isoquinoline derivatives were carried out anticonvulsant activity, with a focusing on GABA‐AT inhibition. In total, 20 novel compounds were synthesized, and characterized with binding assays at GABA‐AT receptor, in the 0.060±0.01 to 5.99±0.10 micromolar range. The ADMET predictions and drug‐like characteristics of α‐pyrazolo‐(aryl/alkyl)methyl‐ketone and pyrazolo[5,1‐a]isoquinoline compounds were identified by pharmacokinetic investigations. Furthermore, the predicted analogue‐enzyme complexes with docking scores were in the range of −7.3 to −10.5, and their SAR analysis was found to be significant of α‐pyrazolo‐(aryl/alkyl)methyl‐ketone and pyrazolo[5,1‐a]isoquinoline structures in medicinal chemistry. Our results revealed that this new structural information will be useful for the future design and synthesis of activity‐based GABA‐AT inhibitors.
Synthesis of BODIPY Organophotocatalysts by Boron Functionalization with Quinine Derivatives and Applications in Asymmetric Photooxygenation
Authors: Coutant Corinne , Fischer Jérôme , Nun Pierrick , Coeffard Vincent 
Published: September 2023

AbstractBoron dipyrromethene (BODIPY) derivatives are key dyes owing to their interesting (electro)chemical and spectroscopic properties. These features have been exploited in various scientific domains such as materials science, biomedicine or organic synthesis. In particular, heavy‐atom containing BODIPY photocatalysts have found widespread applications in photoredox and energy transfer catalysis. The covalent attachment of heavy atoms to the boron dipyrromethene core enables the population of the triplet state through intersystem crossing (ISC), which is involved in the generation of singlet oxygen via triplet‐triplet energy transfer. While the functionalization of the dipyrromethene core has been extensively studied, investigations on boron substitution is far less described. In this work, boron functionalization of diiodo‐BODIPY dyes has enabled the grafting of quinine derivatives leading to a new family of chiral photosensitizers. The photophysical properties and the photostability of these photocatalysts have been investigated in dichloromethane and methanol. Preliminary investigations in asymmetric photooxidative processes have demonstrated the synthetic potential of these BODIPY‐quinine dyes in photoorganocatalysis.
Non‐Steady‐State Symmetry Breaking Growth of Multilayered SnSe2 Nanoplates
Authors: Ran Yutong , Zhao Runni , Meng Chen , Shang Nianze , Sun Shuo , Liu Kaihui , Zhu Hongwei 
Published: September 2023

AbstractThe use of non‐equilibrium growth modes with non‐steady dynamics is extensively explored in bulk materials such as amorphous and polycrystalline materials. Yet, research into the non‐steady‐state (NSS) growth of two‐dimensional (2D) materials is still in its infancy. In this study, multilayered tin selenide (SnSe2) nanoplates are grown by chemical vapor deposition under NSS conditions (modulating carrier gas flow and temperature). Given the facile diffusion and inherent instability of SnSe2, it proves to be an apt candidate for nucleation and growth in NSS scenarios. This leads to the emergence of SnSe2 nanoplates with distinct features (self‐growth twisting, symmetry transformation, interlayer decoupling, homojunction, and large‐area 2D domain), exhibiting pronounced second harmonic generation. The authors’ findings shed light on the growth dynamics of 2D materials, broadening their potential applications in various fields.
Brownian Relaxation Shakes and Breaks Magnetic Iron Oxide‐Polymer Nanocomposites to Release Cargo
Authors: Izak‐Nau Emilia , Niggemann Louisa P. , Göstl Robert 
Published: September 2023

AbstractMagnetic nanoparticles (NPs) are widely employed for remote controlled molecular release applications using alternating magnetic fields (AMF). Yet, they intrinsically generate heat in the process by Néel relaxation limiting their application scope. In contrast, iron oxide NPs larger than ≈15 nm react to AMF by Brownian relaxation resulting in tumbling and shaking. Here, such iron oxide NPs are combined with polymer shells where the shaking motion mechanically agitates and partially detaches the polymer chains, covalently cleaves a fraction of the polymers, and releases the prototypical cargo molecules doxorubicin and curcumin into solution. This heat‐free release mechanism broadens the potential application space of polymer‐functionalized magnetic NP composites.
Electrochemical Oxidation of Furfural on NiMoP/NF: Boosting Current Density with Enhanced Adsorption of Oxygenates
Authors: Zeng Zhiwei , Wu Shutao , Huang Xun , Wei Zidong 
Published: September 2023

AbstractSubstituting the low‐value oxygen evolution reaction (OER) with thermodynamically more favored organic oxidation such as furfural oxidation reaction (FOR) is regarded as a perspective approach to decrease energy cost of hydrogen evolution from water splitting. However, the kinetic of FOR can be even more sluggish than OER under large current density. In this work, a strategy is proposed to accelerate FOR by enhancing the adsorption of oxygenates on active sites. Over the prepared NiMoP/NF anode, only 1.46 V versus RHE is required in furfural solution to achieve 500 mA cm−2, significantly better than the OER activity over commercial RuO2/NF under the same current density (1.57 V vs RHE).