bluuebunny/crossref_metadata_2025_split huggingface dataset:
The characteristics of spelling difficulties for Chinese students
Authors: Zhao Ningning , Li Yanhua , Li Ping , Zhong Kunlin , Desoete Annemie , Zhang Qiuling 
Published: July 2023

Abstract
The study explored the characteristics of students with spelling difficulties in China. According to the international classification of diseases and related health problems Tenth Edition (ICD-10) on the spelling difficulties, there were 7 students with spelling difficulties (means of age = 107.71 months old) selected from total 146 students (means of age = 107.59 months old). The results showed that, spelling difficulties group had more no response errors than the typical speller group. And the SD group and TS group had the same patterns in the no response answers considering the orthographic structure. But the SD group could not make use of the implicitly orthographic structure for the detail while TS group could do. The results confirmed that the SD group had deficit in orthographic-phonographic connections and the information of orthographic structure might work in the whole characters level for SD group. It gave some suggestions for the impairment for the SD group.
The punishment is the reward – why elite Chinese students take supplementary Chinese literacy tutoring despite viewing it as ineffective
Authors: (雨婷 张)  , (小颖 许)  
Published: July 2023

Abstract
Reward and punishment are basic concepts in psychology. To survive better, humans and animals often need to maximize rewards and minimize punishments and threats. The human brain makes judgments about rewards and punishments based on distinguishing among complex environmental factors and makes decisions about future actions accordingly. Chinese students have spent more than a decade of primary and secondary school education with purposeful, fine-grained time management learning with the goal of success on the college entrance exam (Gaokao). The relationship between rewards and punishments for literacy tutoring at the primary and secondary school levels and the decision-making behavior of students and parents is therefore a question worth exploring. The purpose of this paper is to explore the decision-making mechanisms of elite Chinese students’ participation in or withdrawal from literacy tutoring in Chinese and the factors behind the reward and punishment mechanisms through grounded method analysis. The results show that most elite students and their parents do not believe that language literacy tutoring will significantly improve their chances for better college entrance exam scores, but there is a complex relationship between their decision-making behavior in tutoring and the reward and punishment mechanisms. Literacy improvement, emotional values, parent-child support obligations and even face-saving culture all contribute to students’ and parents’ decision-making behaviors. Choosing tutoring that is not seen as likely to improve test scores is a common phenomenon, which suggests that the punishment itself provides the reward that drives decisions to pursue literacy tutoring.
Investigating the effects of varying Accelerative Integrated Method instruction on spoken recall accuracy: a case study with junior primary learners of French
Authors: Carey Michael D. , Rugins Ojars , Grainger Peter R. 
Published: July 2023

Abstract
This study investigated the effect of using the Accelerative Integrated Method (AIM), with or without additional revision and video-guided practice, on junior primary students’ spoken recall accuracy in French. The same beginner AIM French activities were taught by a language specialist to 12 classes in four junior primary levels. Three different conditions of instruction were used each week: (1) one session of AIM instruction, (2) one session of AIM instruction plus one session of revision, and (3) one session of AIM instruction, plus one session of revision, and three sessions of video input. The instruction and revision sessions were facilitated by a language teacher, whereas the video sessions were played by the main class teacher. A two-way ANOVA revealed that Year 1 students benefited from a revision session with the language teacher, but Prep and Year 1 did not benefit from further video exposure. Conversely, the Years 2 and 3 students did not benefit from extra revision with the language teacher, but they did benefit from additional video exposure. Direct observation of the student response to the AIM suggested that the pace of the program needed to be slower for the younger learners.
Modulation of glucose metabolism-related genes in diabetic rats treated with herbal synthetic anti-diabetic compound (α-HSA): insights from transcriptomic profiling
Authors: Khurana Nikhil , Sharma Suman Bala 
Published: July 2023

Abstract

Objectives
Eugenia jambolana is a medicinal plant traditionally used for treating diabetes. The bioactive compound FIIc, which is derived from the fruit pulp of E. jambolana, has been identified and purified as α-HSA. Previous studies have demonstrated that administration of α-HSA for 6 weeks improved glycemic index and dyslipidemia in rats with T2D. This study investigated the molecular mechanism underlying the potential therapeutic effects of α-HSA in experimentally induced diabetic rats.

Methods
Male Wistar rats were divided into four groups: diabetic control, diabetic treated with FIIc, diabetic treated with α-HSA, and diabetic treated with glibenclamide. Over a 6-week experimental period, transcriptomic analysis was conducted on liver, skeletal, and pancreatic tissue samples collected from the rats.

Results
The study findings revealed significant upregulation of genes associated with glucose metabolism and insulin signaling in the groups treated with FIIc and α-HSA, compared to the diabetic control group. Moreover, pro-inflammatory genes were downregulated in these treatment groups. These results indicate that α-HSA has the potential to modulate key metabolic pathways, improve glucose homeostasis, enhance insulin sensitivity, and alleviate inflammation.

Conclusions
This study provides compelling scientific evidence supporting the potential of α-HSA as a therapeutic agent for diabetes treatment. The observed upregulation of genes related to glucose metabolism and insulin signaling, along with the downregulation of pro-inflammatory genes, aligns with the pharmacological activity of α-HSA in controlling glucose homeostasis and improving insulin sensitivity. These findings suggest that α-HSA holds promise as a novel therapeutic approach for managing diabetes and its associated complications.
Dynamic response of a two-story steel structure subjected to earthquake excitation by using deterministic and nondeterministic approaches
Authors: Dows Mustafa Qasim , Al-Baghdadi Hayder A. 
Published: July 2023

Abstract
An earthquake is a random phenomenon in its intensity and frequency content. Since the earthquake is a signal that contains a band of frequencies, each frequency has a different energy. This means that the response of buildings to earthquakes depends not only on the intensity of the earthquake but on its frequency content as well. In this study, two different approaches have been used: deterministic approach which is the time history analysis to show how the intensity of earthquakes affects the building response, and the nondeterministic random vibration approach, which is to clarify the response in the frequency domain and to show the effect of dominant frequencies of the earthquake. Both a prototype and a 1:6 scaled model was used to simulate a two-story steel building. In the experiential part, a shaking table was used to simulate a 1:6 scaled El-Centro 1940 NS earthquake as a base excitation with different intensities (0.05, 0.15, and 0.32g). In the theoretical part, Abaqus software was adopted to simulate the numerical model of the building. The results showed that the deterministic approach may be a non-conservative approach.
Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway
Authors: Duan Qi , Wu Junxia 
Published: July 2023

Abstract
Dihydroartemisinin (DHA) has been found to inhibit the expression of von Willebrand factor (VWF), a marker of endothelial cell injury, but its mechanism in cerebral ischemia/reperfusion (I/R) injury remains obscure. In this study, I/R model was constructed through middle cerebral artery occlusion (MCAO) in rats, followed by DHA administration. The effect of DHA on rat cerebral I/R injury was investigated by 2,3,5-triphenyltetrazolium chloride staining, hematoxylin and eosin staining, TUNEL staining, and Western blot. Brain microvascular endothelial cells (BMVECs) isolated from newborn rats were exposed to oxygen–glucose deprivation/reoxygenation (OGD/R), and then treated with DHA. The results showed that MCAO treatment induced infarction, nerve cell apoptosis, and brain tissue impairment in rats, which was mitigated by DHA. OGD/R inhibited viability and accelerated apoptosis of BMVECs, which was alleviated by DHA. I/R procedures or OGD/R up-regulated expressions of VWF, ATG7, Beclin1, and LC3-II/LC3-I ratio, while down-regulating Occludin, Claudin-5, ZO-1, P62, SIRT1, and FOXO1 expressions in vivo and in vitro; however, these effects of I/R procedures or OGD/R were offset by DHA. VWF overexpression reversed the above effects of DHA on OGD/R-induced BMVECs. In summary, DHA ameliorates cerebral I/R injury in rats by reducing VWF level and activating autophagy-mediated SIRT1/FOXO1 signaling pathway.
Production of high content of N-methyldiethanolamine di-ester via heterogeneous transesterification
Authors: Aziz Haliza Abdul , Yusoff Rozita , Cheng Ngoh Gek , Idris Zainab , Syahirah Ramli Nur Aainaa 
Published: July 2023

Abstract
A heterogeneous transesterification over a Zn-doped CaO catalyst was developed as a new alternative route to conventional homogeneous catalysis for the production of N-methyldiethanolamine-based esterquats. In this study, the optimum heterogeneous transesterification conditions for the production of N-methyldiethanolamine di-ester, a precursor of esterquats, in high yield were determined. At a temperature of 143 °C, a vacuum of 288 mbar, a molar ratio of 2:1 (methyl ester:N-methyldiethanolamine) and a catalyst dosage of 6 %, a maximum N-methyldiethanolamine di-ester yield of 83 % was obtained. The reused catalyst showed consistent activity in three consecutive runs, demonstrating the robustness of the Zn-doped CaO catalyst in the transesterification process. This route can reduce production costs due to the reusability of the catalyst and the elimination of water consumption in the neutralisation process for catalyst removal.
ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein
Authors: Szabo Leonora , Cummins Nadia , Paganetti Paolo , Odermatt Alex , Papassotiropoulos Andreas , Karch Celeste , Götz Jürgen , Eckert Anne , Grimm Amandine 
Published: July 2023

AbstractAbnormal tau protein impairs mitochondrial function, including transport, dynamics, and bioenergetics. Mitochondria interact with the endoplasmic reticulum (ER) via mitochondria‐associated ER membranes (MAMs), which coordinate and modulate many cellular functions, including mitochondrial cholesterol metabolism. Here, we show that abnormal tau loosens the association between the ER and mitochondria in vivo and in vitro. Especially, ER‐mitochondria interactions via vesicle‐associated membrane protein‐associated protein (VAPB)—protein tyrosine phosphatase‐interacting protein 51 (PTPIP51) are decreased in the presence of abnormal tau. Disruption of MAMs in cells with abnormal tau alters the levels of mitochondrial cholesterol and pregnenolone, indicating that conversion of cholesterol into pregnenolone is impaired. Opposite effects are observed in the absence of tau. Besides, targeted metabolomics reveals overall alterations in cholesterol‐related metabolites by tau. The inhibition of GSK3β decreases abnormal tau hyperphosphorylation and increases VAPB–PTPIP51 interactions, restoring mitochondrial cholesterol and pregnenolone levels. This study is the first to highlight a link between tau‐induced impairments in the ER‐mitochondria interaction and cholesterol metabolism.
Computational wind analysis of an open air-inflated membrane structure
Authors: Pool-Blanco Sherly Joanna , Hincz Krisztián 
Published: July 2023

AbstractThe current research aimed to obtain mean pressure distribution over an air-inflated membrane structure using Computational Wind Engineering tools. The steady-state analysis applied the Reynolds-Averaged Navier-Stokes equations with the standard turbulence model. The pressure coefficients were compared with former experimental results to validate the numerical solution. Significant errors were detected close to the critical flow separation points when comparing the numerical results with the wind tunnel tests. However, these errors are local, and the numerical methodology provides accurate results in those areas with minor turbulence motion influence. In general, the numerical solution provided good approximation of the pressure coefficient fields.
ISOLATION AND PURIFICATION OF ISOPRENE FROM CYCLOPENTADIENE
Authors: Shevlyakov Fedor B. , Kildibekova Karina R. , Terechshenko Nikita V. , Litvyakov Ivan S. , Samarkina Aleksandra B. 
Published: July 2023

Isoprene is a basic monomer in the petrochemical industry. It is used in the synthetic rubber production for the manufacture of rubber products for the electrical, aviation and engineering industries, for the manufacture of food and medical products. In the Republic of Bashkortostan, Sintez-Kauchuk OJSC (Sterlitamak) produces isoprene by the two-stage dehydrogenation of isopentane with an annual product output of hundreds of thousands of tons. The disadvantage of this technology for producing isoprene is the significant content of impurities in raw isoprene, which seriously affect the kinetics of polymerization and the quality of the final product. Of all the impurities present in the monomer, cyclopentadiene is the most detrimental to the stereoregular polymerization process. Its content in isoprene should not exceed 0.0001 % wt. Due to the urgency of the problem, a technical solution was developed to remove cyclopentadiene impurities from monomers.Currently, there is a problem of accumulation of cyclopentadiene in the system of purification and treatment of isoprene at the operating production. The paper proposes to purify isoprene from cyclopentadiene before the stage of extractive distillation. This purification method allows to reduce the content of cyclopentadiene in the isoprene-isoamylene fraction from 0.10 % wt. to 0.00014 % wt, which reduces its concentration in all recycle flows of the isoprene isolation and purification system. To implement this solution, laboratory experiments were carried out to purify the isoamylene-isoprene fraction formed at the second stage of isopentane dehydrogenation. In order to assess the energy efficiency of the studied method for reducing cyclopentadiene, a computer model of the isoprene isolation and purification process was built in the Honeywell Unisim Design software environment.
Digitalization in maxillofacial prosthodontics- A review
Authors: Bhujbal Rushikesh Bhau , Bakrolwala Husbana , Jurel Sunit Kumar , Chand Pooran , Singh Raghuwar Dayal 
Published: July 2023

Maxillofacial deformities that result from trauma, developmental abnormalities, destructive cancer surgeries, surgically operated mucormycosis can be difficult for a person to deal with as it affects the esthetics and functions and further degrades their quality of life. Hence, maxillofacial prosthesis not only corrects the deformity but also boost the self-confidence so that the patient can live his/ her life to the fullest. The creation of prostheses is currently undergoing a revolution, crediting the new, cutting-edge technologies including 3D modelling, printing, and imaging. These innovative methods are replacing the manual, labour-intensive, and expensive traditional methods of producing prosthetics with faster, less expensive methods that enable the creation of patient-specific prostheses. Our research aim to provide an update on the digital workflow of fabricating a maxillofacial prosthesis, highlighting the data collecting techniques at hand for extraoral, intraoral, and complex maxillofacial abnormalities, as well as evaluating the software’s used for data processing and designing. Also as the demand for a digital approach to craniofacial rehabilitation increases, it may be seen that the work of software designers will be at demand to help create accessible and user-friendly modules similar to those used in dental laboratories. As the demand for a digital approach to craniofacial rehabilitation is increasing, it has been noticed that assistance from the software designer will be required in future to produce user-friendly and accessible modules comparable to those used in dentistry laboratories
Comparative evaluation of inter-commisural width, combined mesio-distal width of anterior teeth and their association with gender in school going children of Ranchi city -A pilot study
Authors: Ahuja Annapurna , Ahuja Vipin , Swati Murmu  , Agrawal Rohit 
Published: July 2023

The aim of the present study was to evaluate and determine the correlation between the intercommisural width, combined mesiodistal width of the maxillary and mandibular anterior teeth, its site variation with gender in school going children with permanent dentition. A total number of 32 children aged 12 to 15 years were selected for the study. The children were randomly selected using lottery method out of 50 school students fulfilling inclusion criteria. The participants were comfortably seated on a dental chair in an upright position and were asked to relax during the measurement. The inter-commisural width was measured between left and right commissure of mouth using metallic scale. The maxillary and mandibular impressions were recorded; study models with bases were made. The combined mesiodistal width of the maxillary and mandibular anterior teeth were recorded using digital vernier caliper. The parameters were analyzed with gender and compared. Data collected was tabulated and statistical analysis was performed in SPSS software version 20.0 Descriptive statistics were calculated (mean and standard deviation) and for inferential statistics, Pearson’s correlation coefficient was applied; P value &#60;0.05 was considered to be significant. There is a definite correlation between intercommisural width and combined mesiodistal width of the maxillary and mandibular anterior teeth with gender.
Pedagogical implications of a blended learning model at Temouchent University
Authors: Fehaima Amaria 
Published: July 2023

With the expansion of technology and the rapid spread of Internet use around the world, the supply and demand for education have shifted. In some cases, demographic changes have led to population increases, posing challenges to higher education in terms of demand and supply of education, especially given the global challenges of Covid19. Higher education institutions are researching and adopting pedagogical approaches to meet the changing needs of education in response to various challenges, especially with Covid19. E-learning is one of these modes. This work aims to explore the effectiveness of this new model (mixed education) in English language departments, in particular for third-Year students. It explores the pedagogical issues of e-learning in education for development thus it offers a descriptive study between face-to-face and distance education, which highlights the characteristics and difficulties encountered by EFL Learners. As a result of the study, students found obstacles that hinder course continuity, and they are detailed in the study.
Keywords: Blended learning; EFL Learners; higher education; students’ achievement.
A psycholinguistics view on a child’s speech production in babbling stage: A case study
Authors: Suryanto Puput Jianggimahastu Larastika , Husaini Rizqi 
Published: July 2023

This study aims to examine a baby's babbling child's speech production seen from psycholinguistics view. It also aims to reveal the phonological organization, contextualize meaning, and decipher meaning of the baby’s babbling stage. The participant was an infant who was at the stage of babbling at eight months old. This study used case study as the research design. Moreover, the data was collected by using direct observation, document and parents’ interview. The results shows that there were 99 patterns in the baby’s babbling stage. Furthermore, the babbling topic occurred in several contexts, with each babbling having a varied meaning depending on the situation.
PENGEMBANGAN VIDEO PENYULUHAN BAHASA KASIH REMAJA PUTRI MENGGUNAKAN CANVA DI PUSAT PEMBELAJARAN KELUARGA KOTA BANDUNG
Authors: Razmuliani Novia , Achdiani Yani , Ana Ana 
Published: July 2023

The study was set against a background of the development of digital technology that supported the quality of spreading information in outreach activities at the Bandung family learning center. Multifaceted technological developments provide ease for the medium of counseling videos. The purpose of this study aims to develop fatherhood videos on the language of love using the canva in the family learning center to teach fathers the socialization needed to educate fathers in order to understand and express their relationships with young women in order to enhance the relationship of fatherhood and child in order to secure the relationship of fatherless to unfurl the growing emotional mental growth of fatherless A child as well as father's diversity in the family, this can be conveyed by counseling. The study used to research and development (r&d) methods with planning, production, and development models (PPE). The data-gathering technique was done with demand analysis, interviews, and expert judgment with two media experts, one materials expert, and one dad school practitioner. The findings of research on judgment point out that the study on the language of young women's love development used canva in the Bandung family study center was deemed worthy of both material and media, so that it could be used as a medium to educate father's school activities in PUSPAGA.

Abstrak
Penelitian ini dilatarbelakangi oleh perkembangan teknologi digital yang mendukung kualitas penyebaran informasi dalam kegiatan penyuluhan di Pusat Pembelajaran Keluarga Kota Bandung. Perkembangan teknologi yang beragam memberikan kemudahan pada media penyuluhan berupa video penyuluhan. Tujuan penelitian ini bermaksud untuk mengembangkan video penyuluhan terkait peran ayah terhadap remaja putri mengenai Bahasa Kasih menggunakan canva di Pusat Pembelajaran Keluarga untuk memberikan sosialisasi pada ayah yang perlu diajarkan dalam rangka mengedukasi para ayah agar dapat memahami dan mengekspresikan afeksinya pada remaja putri guna mempererat hubungan kedekaatan ayah dan anak agar terhidar dari fatherless yang mengakibatkan tidak maksimalnya tumbuh kembang mental emosi dari seorang anak serta keberfungsian fathering dalam keluarga, hal ini dapat disampaikan melalui penyuluhan. Penelitian ini menggunakan metode Research and Development (R&D) dengan model Planning, Production, and Evaluation (PPE). Teknik pengumpulan data dilakukan dengan analisis kebutuhan, wawancara dan expert judgment dengan dua orang ahli media, satu orang ahli materi, dan satu orang praktisi Sekolah Ayah. Hasil temuan penelitian yang diperoleh dari hasil expert judgment menunjukan bahwa penelitian yang berjudul Pengembangan Video Bahasa Kasih Remaja Putri Menggunakan Canva di Pusat Pembelajaran Keluarga Kota Bandung dinyatakan dengan kriteria layak, baik segi materi maupun media, sehingga dapat digunakan sebagai media penyuluhan dalam kegiatan Sekolah Ayah di PUSPAGA.