bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two Concepts One Issue: A Bibliometric Analysis of Climate Change and Climate Crisis Concepts
Authors: Güney İsmet , Çelik Mehmet Ali , Rijsdijk Kenneth F. , çelik Emrah 
Published: January 2023

Abstract
This research aims to analyse and discuss the different conceptualization of anthropogenic global warming (AGW) in academic publications. The main question is to understand how different approaches to climate change is addressed in the literature. In order to answer this research question, a sample was created from Scopus literature database. Analysis was performed using the VOSviewer program on a data set consisting of keywords and citation information. The findings show that the perspectives of the studies that adress the same topic with different terms such as “climate change” and “climate crisis” are fundamentally different. Studies using the concept of “climate change” take a more techno-scientific methodological approach linking AGW to concepts such as drought, sea level changes, extreme weather events and agriculture. In contrast studies that use the concept of “climate crisis” relate the AGW to climate justice and concepts such as neoliberalism. It is noteworthy that studies using the concept of “climate crisis” are mostly studies carried out by social sciences studies that deal with the problem in an interdisciplinary political and social context whereas “climate change” is used by physical science studies including climatology, earth science and ecology. Given the traditional separation of these disciplines it is not surprising that two different nomenclatures were used to address the AGW problem. We argue that the concept “climate crisis” is capturing the urgency of the AGW and that in order to find interdisciplinary solutions both insights from physical and humanity sciences must be combined.
Architecture of Smart Hospital Information Systems based on IoT and Blockchain
Authors: Alihamidi Imam , Deroussi Anass , Charaf Lalla Amina , REOUKADJI Dior MASRANE , Madi Abdessalam Ait , addaim Adnane 
Published: January 2023

Abstract
Nowadays, information represents an important resource for any organization and to ensure its management, it is important to set up an information system. The latter being essential in various fields, it can bring improvements in the care of patients and in the quality of health services. However, the use of information and communication technologies on the quality of health services was exclusive in developed countries. It is with this in mind that we have focused our study on the proposal of architecture to make hospital intelligent based on the Internet of Things (IoT) and the Blockchain. To do this, we used three databases namely Scopus, Web of Science and PubMed. First, we collected references to open-source Hospital Information Systems (OS HIS) and we were able to extract thirteen popular projects of which seven are active and 6 are not. Then, we continued our study with the seven active projects. Second, we collected references to IoT architectures for healthcare and after extensive reading we opted for a three-layer architecture (perception layer, network layer and application layer). Third, we collected references to lightweight blockchains and after in-depth reading of the documents found, we selected the Hyperledger foundation which was created to ensure the promotion of blockchain through an open-source ecosystem. As a result, we were able to come up with a three-layer architecture which is on the concepts of IoT and Blockchain. The proposed work is promising and can be used as a reference for the deployment of a hospital information system in an environment with limited resources.
Superposition extreme high-altitude exposure (8848m) forms episodic memory of LIPN and PLCH1 genes associated
Authors: Zhang Shixuan , Duoji Zhuoma , Yang La , Qiangba Danzeng , De Yang , Hu Xiaoxi , Jiang Zeyu , Hou Dandan , Hu Zixin , Basang Zhuoma 
Published: January 2023

Abstract
Background: Extreme environmental stress interactions with DNA methylation may produce episodic memory for environmental adaptation.
Methods: In the present study, 64 volunteers born and living at an altitude of 4,700 m were recruited, including 32 volunteers who were repeatedly exposed to high altitudes (up to 8,848 m, up to 11 times). We explored the changes in the genes hosting 741,489 CpG loci as well as 39 physiological phenotypes under superposition extreme high-altitude exposure (SEH).
Results: 13 CpG for 11 genes were identified with tightly linked networks to five phenotypes. Bayesian causal network analysis suggests network properties of 15 SEH-related phenotypic networks and MP-SSN, reflected in increased robustness with an increasing number of SEH exposures, suggesting environmental resistance. In addition, we explored the characteristics under SEH of the MP-SSN network nodes in populations with significant differences in SpO2 (n High-adaptability= 28; n Low-adaptability= 36) and found concomitant changes in five phenotypes and CpG methylation, while the changes occurred earlier in the high SpO2 population (Climbing age = 5 times).
Conclusion: Considering evidence from the literature and database validation, we suggest that the promoter and enhancer regions of the LIPN and PLCH1 genes may be influenced by methylation memory generated by light environment exposure during SEH exposure. Methylation memory may have an effect on the phenotype by influencing the action of the pathway in which the gene is located, thus advancing the environmental adaptation status of SEH, such as SpO2 and SP.
Z-number Decision Tree and Its Appliction
Authors: Fang Yue , Wu Tao , Liu Shuai , Zhang Zui 
Published: January 2023

Abstract
Fuzzy decision tree(FDT) is an expansion and improvement of decision tree, which expands the application scope of decision tree to deal with the uncertainty and extracts classification rules efficiently. However, there are some problems in the process of sample attributes fuzzifying, such as information loss and the influence of strong personal subjectivity on the results. To solve these problems, a fuzzy decision tree algorithm based on Z-number(Z-FDT) is put forward. we propose a method to construct Z-number, first, membership functions is defined to fuzzify the data set and describe the size of the probability measure of the fuzzy set, then the cluster centers of multi-dimensional data are extracted ,using the fuzzy clustering algorithm., the membership function and cluster centers of different categories fuzzy partition the sample data set based on the features of the sample, and obtain the fuzzy sets. Finally, based on the definition of Z-number, fuzzy sets are constructed into Z-numbers. After the multidimensional data set is transformed into Z-numbers, the uncertainty measure of Z-number is used to select appropriate features to partition the data set, until the stop condition is met. Z-FDT can directly classify and predict samples with continuous attribute values, and has good generalization ability and relatively stable results, at the last, this will be confirmed through the comparative experiment with ID3, Cart and Fuzzy ID3.
Do the Academician Independent Directors Promote Green Innovation in Enterprises?
Authors: Zhang Luxiu , Zhang Yingjie , Li Ning , Zhang Qianwen 
Published: January 2023

Abstract

Using the manually collated data on the employment of academicians as independent directors by Shanghai and Shenzhen A-share listed firms from 2010 to 2020,the role and impact mechanism of academician independent directors on enterprise green innovation were empirically analyzed. The research shows that the academician independent directors promote green innovation of enterprises by alleviating corporate financing constraints,increasing corporate R&D investment and alleviating managerial myopia, and their role in promoting green invention patents is greater than that of green utility model patents.The academician independent directors will improve the green innovation level of enterprises in non-heavy polluting industries and enterprises in the eastern region,and the nature of propert rights and the degree of marketization will strengthen their role in promoting green innovation.
Computed tomography imaging features and diagnostic points for epithelium angiomyolipoma：a retrospective analysis
Authors: Yang Yuling , Yu Shuiquan , Zou Bin , Chen Qifeng , Lin Zilang , Guo Yongfei 
Published: January 2023

Abstract
Background The incidence of epithelium angiomyolipoma is extremely low, and the accurate diagnosis of pre-treatment imaging is clinically significant for treatment choice and patient prognosis. This study analyzed the computed tomography (CT) imaging features of patients with epithelium angiomyolipoma (EAML) and explored the causes of misdiagnosis to improve the accuracy of imaging diagnosis.
Methods This study was a retrospective analysis of the clinical manifestations, imaging data, and characteristics of 13 patients (14 lesions) with EAML in our hospital from March 2011 to March 2021; further, we performed a review of the domestic and international literature on its CT imaging characteristics.
Results The clinical presentations included abdominal pain, abdominal discomfort, or physical examination findings. All patients had a single lesion, except for one patient with one lesion in each kidney and one patient with additional renal vascular smooth muscle lipomas. Half of the lesions occurred in the left/right kidney, eight occurred in the middle of the kidney (57.1%), five (42.9%) occurred in the lower pole, 10 (71.4%) occurred mainly in the renal cortex, 10 (71.4%) showed exophytic growth, four (28.5%) were intraparenchymal, nine (64.3%) showed equal or slightly high density, eight (57.1%) had measurable fat components, 13 (92.9%) lacked calcification, 11 (84.6%) were round or oval, and 10 (71.4%) showed wedge-shaped signs on three-dimensional reconstruction. Seven lesions showed an early washout pattern (50.0%), seven (50.0%) showed a prolonged enhancement pattern, 10 (71.4%) showed inhomogeneous enhancement, and eight (57.1%) showed tumor neovascularization on enhancement scans. No lesions were correctly diagnosed preoperatively as epithelioid vascular smooth muscle lipoma. Four were mentioned in the differential diagnosis as requiring differentiation from fat-depleted vascular smooth muscle lipoma.
Conclusions The diagnostic accuracy of EAML imaging is low, the clinical manifestations are non-specific, and the imaging manifestations are difficult to distinguish from renal cancer or vascular smooth muscle lipoma. Lesions showed equal or slightly high density on CT scans, starting from the renal cortex, with exophytic growth, “wedge sign,” and prolonged enhancement patterns. This disease should be considered in cases with early washout patterns with more uniform enhancement or intratumoral neoplasia in the lesion.
High capacity clinical SARS-CoV-2 molecular testing using combinatorial pooling
Authors: Zismanov Shosh , Shalem Bar , Margolin-Miller Yulia , Rosin-Grunewald Dalia , Adar Roy , Keren-Naus Ayelet , Amichay Doron , Ben-Dor Anat , Shemer-Avni Yonat , Porgador Angel , Shental Noam , Hertz Tomer 
Published: January 2023

Abstract

The SARS-CoV-2 pandemic led to unprecedented testing demands, causing significant testing delays globally. One strategy used for increasing testing capacity was pooled-testing, using a two-stage technique first introduced during WWII. Here we report the development, validation and clinical application of P-BEST - a single-stage pooled-testing strategy that was approved for clinical use in Israel. P-BEST was clinically evaluated using 3,636 side-by-side tests and was able to correctly detect all positive samples and accurately estimate their Ct value. P-BEST was then used to clinically test 837,138 samples using 270,095 PCR tests - a 3.1 fold reduction in the number of tests. Importantly, P-BEST was also used during the Alpha and Delta waves, when positivity rates exceeded 10%, rendering traditional pooling non-practical. We also describe a tablet-based solution that allows performing manual single-stage pooling in settings where liquid dispensing robots are not available. Our data provides a proof-of-concept for large-scale clinical implementation of single-stage pooled-testing for continuous surveillance of multiple pathogens with reduced test costs, and as an important tool for increasing testing efficiency during pandemic outbreaks.
Crystallization of Hydrogenated Amorphous Silicon Thin Films Using Combined Continuous Wave Laser and Thermal Annealing
Authors: Shariah Adnan 
Published: January 2023

Abstract

Hydrogenated amorphous silicon (a-Si:H) films were deposited using the plasma-enhanced chemical vapor deposition (PECVD) process on Corning glass substrates. An aluminum overcoat was deposited on the films. The specimens were irradiated with a continuous wave Ar + laser beam of varying power density and duration. The samples were then annealed at 250 oC for 15 minutes to convert the amorphous silicon into polysilicon film. The grain size of the polycrystalline silicon films varies by varying the laser power density and the exposure time. The polysilicon grains acquired diameters ranging from 0.4 to 1.25 µm when the laser power density was set between 74.7 W/cm2 and 94.3 W/cm2. The grains with a size ranging between 1 and 2.5 µm showed plate-like and dendritic-like configurations when laser power densities changed between 31.4 and 74.7 W/cm2. The XRD analysis revealed polycrystalline silicon with expected relative strengths.
Uncontrolled Blood Pressure and Associated Factors in Adult Hypertensive Patients Undergoing Follow-Up at Public Health Facility Ambulatory Clinics in Bishoftu Town, Ethiopia: A Multi-Center Study
Authors: Solomon Menawork , Bekele Nardos Tilahun , Getahun Mihiret Shawel , Negussie Yohannes Mekuria , Gurara Abenet Menene 
Published: January 2023

Abstract
Introduction

Uncontrolled blood pressure is an important medical and public health problem in developing countries like Ethiopia. Improving the management of hypertension requires a better comprehension of the factors influencing blood pressure control and the application of interventions. But in clinical practice, blood pressure is still not adequately controlled. Thus, this study aimed to assess uncontrolled blood pressure and associated among adult hypertensive patients on follow-up at public health facility ambulatory clinics in Bishoftu, Ethiopia.

Methods

A hospital-based cross-sectional study was conducted among 398 adult hypertensive patients from April 1 to May 31, 2022. Systematic random sampling was used to select study participants. Data were collected using an interviewer-administered, semi-structured questionnaire and chart review. The collected data were entered into Epi-info version 7 and analyzed by Statistical Package for Social Science (SPSS) version 26. Binary logistic regression analysis was used to model the association between dependent and independent variables. An adjusted odds ratio and 95% confidence interval were used to measure the strength of the association. Finally, the statistical significance was declared at a p-value < 0.05.

Result

Of the total study participants, 249(62.6%) were male. The mean age was 62.26 ± 11.55 years. The overall proportion of uncontrolled blood pressure was 58.8% (95% CI: 54–64). Salt intake (AOR = 2.51; 95% CI: 1.49–4.24), lack of physical activity (AOR = 1.40; 95% CI: 1.20–9.62), habitual coffee consumption (AOR = 4.52; 95% CI: 2.67–7.64), higher BMI (AOR = 2.08; 95% CI: 1.24–3.49), and non-adherence to antihypertensive medications (AOR = 2.31; 95% CI: 1.3–3.89) were independent predictors of uncontrolled blood pressure.

Conclusion

More than half of the hypertensive patients in this study had uncontrolled blood pressure. Healthcare providers and other accountable stakeholders should urge patients to follow salt restriction, physical activity, and antihypertensive medication regimes. Reduced coffee consumption and weight maintenance are other crucial blood pressure control measures.
MicroRNAs (miRNAs) Role in Hypertension: Pathogenesis and Promising Therapeutics
Authors: Shaheen Nour , Diab Rehab Adel , Desouki Mariam Tarek , Shaheen Ahmed , Elmasry Mohamed , Rebei Mayssa , Swed Sarya 
Published: January 2023

Abstract
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a crucial role in regulating various cellular processes, including cell proliferation, differentiation, apoptosis, and disease development. Recent studies have highlighted the importance of miRNAs in the development and progression of essential hypertension, a common form of high blood pressure that affects millions of individuals worldwide. The molecular mechanisms by which miRNAs regulate hypertension are complex and multifaceted. MiRNAs target the 3' untranslated regions of mRNA molecules, thereby regulating the synthesis of specific proteins involved in cardiovascular function. For instance, miRNAs are known to regulate the expression of genes involved in blood vessel tone, cardiac function, and inflammation.
The growing body of research on miRNAs in hypertension has highlighted their potential as therapeutic targets for managing this condition. Studies have shown that miRNA-based therapies can modulate the expression of key genes involved in hypertension, leading to improvements in blood pressure and cardiovascular function. However, more research is needed to fully understand the mechanisms of miRNA-mediated hypertension and to develop effective therapeutic strategies.
In summary, this review highlights the current understanding of the role of miRNAs in essential hypertension, including their molecular mechanisms and potential therapeutic applications. Further research is needed to fully understand the impact of miRNAs on hypertension and to develop new treatments for this common and debilitating condition.
Preliminary insights into the molecular mechanism of energy metabolism on sex differentiation in chickens based on transcriptome sequencing
Authors: Zhao Zongyi , Zuo Qisheng , Cheng Fufu , Hu Cai , Wu Yuhui , Geng Qingqing , Wu Rongfeng , Wang Yingjie , Zhang Wenhui , Niu Yingjie , Sun Hongyan , Jin Kai , Li Bichun , Zhang Yani 
Published: January 2023

Abstract
Mammalians sex determination is well-known, and sophisticated mechanisms to sex control have been developed. However, effective sex control in poultry has not yet been developed. Through RNA-sequencing of the male gonads and ovarian tissues of chicken embryos up to 18.5 days, we identified the primary metabolic factors affecting male and female sex differentiation and gonadal development. Pkm2, an essential glycolysis-related protein, influences sex differentiation in chickens via Gapdh, a crucial hormone gene. Glycolysis-related sex regulation also involves epigenetic alterations such as transcription factor (Srf, Myb, Tead1), acetylation (Hdac3), and phosphorylation (Nfkbia, Ikbkb) modifications. Our findings support the concept that glycolysis and oxidative phosphorylation contribute upstream to sexual phenotypic development and maintenance.
Fe-Ti oxides/carbon composites derived from temperature-dependent solid-state reaction between MOFs core and TiO2 shell for broadband microwave absorption
Authors: Liu Wei , Cao Ronggan , Duan Pengtao , Ding Yue , Su Hailin , Zhang Xuebin , Zou Zhongqiu , Wang Jinzhi 
Published: January 2023

Abstract

Regulating phase composition and dispersion state of oxide particles inside metal-organic frameworks-derived carbon composite holds enormous potential in enhancing dielectric property and microwave absorption performance. Herein, solid state reaction between Fe-bdc nanorod and TiO2 shell has been used to synthesize a series of Fe-Ti oxides/carbon (FTO/C) composites at different annealing temperatures. The results show that with the increase of temperature, the grain size of oxide particles, which tend to distribute in the center of carbon rod, has increased, resulting in the formation of continuous conductive surface caron layer. Meanwhile, the aspect ratio of carbon rod would decrease, which would hinder the construction of conductive path in paraffin matrix. At lower temperature, internal oxide particles are less crystallized (Fe2.5Ti0.5)1.04O4, which may induce obvious dipole polarization. While at higher temperature, phase conversion from (Fe2.5Ti0.5)1.04O4 to Fe2TiO4 and FeTiO3 would bring about more interfaces, which generate strong interfacial polarization. Therefore, dielectric loss of as-prepared FTO/C composites would be enhanced with rising temperature until 700 oC, and impedance matching condition would always be improved with increasing temperature, in terms of lowest matching thickness in whole Ku or X bands. Consequently, S-700 owns a broad effective absorption bandwidth (EAB) of 6.84 GHz at 2.2 mm, covering whole Ku band and S-800 owns a large EAB of 4.16 GHz at 2.8 mm, covering whole X band. This work may provide novel insights into the design of metal-organic frameworks-derived carbon composite with desired dielectric properties through controlling the composition and dispersion of inner oxide particles.
Acceptance and utilization efficiency of a purple durum wheat genotype by Sitophilus granarius (L.)
Authors: D'Isita Ilaria , Palma Antonella Marta Di , De Vita Pasquale , Germinara Giacinto Salvatore 
Published: January 2023

Abstract
The granary weevil, Sitophilus granarius (Coleoptera, Curculionide) is one of the most damaging primary pest of stored cereals worldwide. Flavonoids are a major class of secondary plant metabolites which modulate feeding response and growth rate in insects. In the present study, the susceptibility to the granary weevil of the durum wheat T1303, an anthocyanin-rich purple genotype, in comparison with the yellow commercial durum (Ofanto) and bread (Mec) wheat varieties was evaluated. Moreover, to investigate the feeding response and food utilisation efficiency by adult insects, nutritional indices were calculated by means of flour disk bioassays. The total number of F1 progeny, the female parental offspring, and mean food consumption by an insect recorder for the T1303 genotype were significantly lower compared to yellow wheat varieties indicating different level of susceptibility to S. granariusattacks. Actually, T1303 induced positive values of Food Deterrence Index (FDI) indicating deterrence. Besides, Relative Grow Rate (RGR) and Efficiency Conversion of Ingested Food (ECI) indices were negative for T1303 and positive for both yellow wheat varieties indicating a decrease and an increase of insect body weight during the experiment, respectively. Finally, adult mortality of insects fed on T1303 whole flour disks was significantly higher than those observed for insects feed on yellow wheat varieties after six-day exposure. These results strongly suggested antifeedant and toxic effects of anthocyanins accumulated in the pericarp of T1303 kernels against granary weevils offering new insights into the mechanism of host acceptance and food utilization by this pest. This information would be useful to identify antifeedant flavonoids as well as in breeding programs aimed at developing varietal resistance-based strategies against stored-product insect pests.