bluuebunny/crossref_metadata_2025_split huggingface dataset:
Free-breathing 3D Stack-of-Stars Gradient Echo Sequence in MR-guided Percutaneous Liver Interventions: Evaluation of Workflow and Diagnostic Quality
Authors: Glandorf Julian , Horstmann Dominik , Düx Daniel Markus , Wacker Frank , Gutberlet Marcel , Hensen Bennet 
Published: January 2023

Abstract
Purpose
To evaluate workflow efficiency and diagnostic quality of a free-breathing 3D stack-of-stars gradient echo (Radial GRE) sequence compared to a breath-hold 3D Cartesian gradient echo (Cartesian GRE) sequence for needle position control in MR-guided liver interventions.

Materials and Methods
12 MR-guided liver interventions were performed on a 1.5 T Siemens Aera and analyzed retrospectively. 15 series of the Radial GRE sequence were compared to 14 series of the Cartesian GRE sequence regarding the time interval between two consecutive live-scans for needle tracking (Tracking-2-Tracking-Time). The quality of both sequences was compared by the SNR within comparable slices in liver and tumor ROIs. The CNR was calculated by subtraction of the SNR values. Subjective image quality scores of three radiologists were assessed and inter-rater reliability was tested by Fleiss’ kappa. Values are given as mean ± SD. P-values < 0.05 were considered as significant.

Results
The median Tracking-2-Tracking-Time was significantly shorter for the Radial GRE sequence, 185 ± 42 s vs. 212 ± 142 s (p = 0.04) and the median SNR of the liver and tumor ROIs were significantly higher in the Radial GRE sequence, 249 ± 92 vs. 109 ± 67 (p = 0.03) and 165 ± 74 vs. 77 ± 43 (p = 0.02). CNR between tumor and liver ROIs showed a tendency to be higher for the Radial GRE sequence without significance, 68 ± 48 vs. 49 ± 32 (p = 0.28). Mean subjective image quality was 3.33 ± 1.08 vs. 2.62 ± 0.95 comparing Radial and Cartesian GRE with a Fleiss’ kappa of 0.39 representing fair inter-rater reliability.

Conclusion
A free-breathing 3D stack-of-stars gradient echo sequence can simplify the workflow and reduce intervention time, while providing superior image quality. Under local anesthesia, it increases patient comfort and reduces potential risks for needle dislocations in MR-guided liver interventions by avoiding respiratory arrests for needle position control.
Fetal MRI radiomics: non-invasive and reproducible quantification of human lung maturity
Authors: Prayer Florian , Watzenböck Martin L. , Heidinger Benedikt H. , Rainer Julian , Schmidbauer Victor , Prosch Helmut , Ulm Barbara , Rubesova Erika , Prayer Daniela , Kasprian Gregor 
Published: January 2023

Abstract
Objectives
To assess the reproducibility of radiomics features extracted from the developing lung in repeated in-vivo fetal MRI acquisitions.

Methods
In-vivo MRI (1.5 Tesla) scans of 30 fetuses, each including two axial and one coronal T2-weighted sequences of the whole lung with all other acquisition parameters kept constant, were retrospectively identified. Manual segmentation of the lungs was performed using ITK-Snap. One hundred radiomics features were extracted from fetal lung MRI data using Pyradiomics, resulting in 90 datasets. Intra-class correlation coefficients (ICC) of radiomics features were calculated between baseline and repeat axial acquisitions and between baseline axial and coronal acquisitions.

Results
MRI data of 30 fetuses (12 [40%] females, 18 [60%] males) at a median gestational age of 24 + 5 gestational weeks plus days (GW) (interquartile range [IQR] 3 + 3 GW, range 21 + 1 to 32 + 6 GW) were included. Median ICC of radiomics features between baseline and repeat axial MR acquisitions was 0.92 (IQR 0.13, range 0.33 to 1), with 60 features exhibiting excellent (ICC > 0.9), 27 good (> 0.75–0.9), twelve moderate (0.5–0.75), and one poor (ICC < 0.5) reproducibility. Median ICC of radiomics features between baseline axial and coronal MR acquisitions was 0.79 (IQR 0.15, range 0.2 to 1), with 20 features exhibiting excellent, 47 good, 29 moderate, and four poor reproducibility.

Conclusion
Standardized in-vivo fetal MRI allows reproducible extraction of lung radiomics features. In the future, radiomics analysis may improve diagnostic and prognostic yield of fetal MRI in normal and pathologic lung development.

Key Points
• Non-invasive fetal MRI acquired using a standardized protocol allows reproducible extraction of radiomics features from the developing lung for objective tissue characterization.
• Alteration of imaging plane between fetal MRI acquisitions has a negative impact on lung radiomics feature reproducibility.
• Fetal MRI radiomics features reflecting the microstructure and shape of the fetal lung could complement observed-to-expected lung volume in the prediction of postnatal outcome and optimal treatment of fetuses with abnormal lung development in the future.
Respiratory morbidity in preschool and school-age children born very preterm and its association with parents’ health-related quality of life and family functioning
Authors: Peralta Gabriela P. , Piatti Raffaela , Haile Sarah R. , Adams Mark , Bassler Dirk , Moeller Alexander , Natalucci Giancarlo , Kriemler Susi 
Published: January 2023

AbstractThe purpose of this study is to describe the prevalence and severity of respiratory symptoms in children born very preterm and to assess their association with parents’ health-related quality of life (HRQoL) and family functioning. We conducted a cross-sectional study and recruited children born less than 32 weeks’ gestation between January 2006 and December 2019, in the greater Zurich area, Switzerland. Between May and December 2021, parents were invited to complete an online survey for their preterm child and for a control term born (≥ 37 weeks’ gestation) sibling aged 1 to 18 years. We used a validated questionnaire to assess respiratory symptoms and the
Pediatrics Quality of Life Family Impact Module (PedsQL FIM) to assess parents’ HRQoL and family functioning. The survey was completed for 616 very preterm children (99 with bronchopulmonary dysplasia (BPD)) and 180 controls. Girls made up 45% (46% in controls) of the sample, and 63% (60% in controls) of participants were aged 6 to 18 years (school-age). Very preterm children reported a higher risk of respiratory symptoms than controls, especially preschoolers and those with moderate-to-severe BPD. Parents of children with “mild” and “moderate-severe” respiratory symptoms had on average −3.9 (95%CI: −6.6 to −1.1) and −8.2 (−11.2 to −5.2) lower PedsQL FIM total score, respectively, than parents of children with no symptoms. The same pattern was observed after stratifying by age categories. Conclusions: Our study suggests that respiratory morbidity in very preterm children has a negative impact on parents’ HRQoL and family functioning, even beyond the first years of life.

What is Known:• The burden of respiratory morbidity associated with very premature birth is high and last far beyond the neonatal period.• Respiratory morbidity contributes to lower health-related quality of life (HRQoL) in parents of very preterm children in early infancy.

What is New:• Respiratory morbidity in very preterm children has a negative impact on parents’ HRQoL and family functioning beyond the first years of life.• Parents of very preterm children with moderate and severe respiratory symptoms are the ones who report lower scores, both for preschool and school-age children.
Prognostic value of MR-detected mandibular nerve involvement: potential indication for future individual induction chemotherapy in T4 nasopharyngeal carcinoma
Authors: Huang Wenjie , Li Shuqi , Luo Chao , Liang Zhiying , Zhou Shumin , Li Haojiang , Cai Yi , Liang Shaobo , Ruan Guangying , Cai Peiqiang , Liu Lizhi 
Published: January 2023

Abstract
Purpose
To investigate the prognostic significance of MR-detected mandibular nerve involvement (MNI) and its value for induction chemotherapy (IC) administration in patients with nasopharyngeal carcinoma (NPC) and T4 disease.

Methods
This retrospective study enrolled 792 non-metastatic, biopsy-proven NPC patients. Univariate and multivariate analysis were used to evaluate potential prognosticators. The inter-observer agreement was assessed by the kappa values.

Results
MR-detected MNI was observed in 141 (72.3%) patients among 195 patients with T4 disease, with excellent agreement between the readers (kappa = 0.926). Patients with MR-detected MNI presented better 5-year overall survival (OS) (hazard ratio [HR], 0.40; P = 0.006) than those with MR-negative MNI. Of these patients, IC treatment was verified as an independent factor (HR: 0.35; P = 0.014) with preferable effect on OS.

Conclusion
MR-detected MNI could serve as an independent favorable prognostic predictor for OS in NPC patients with stage T4, which should be considered for stratifying these patients for IC administration.
Telestration with augmented reality improves surgical performance through gaze guidance
Authors: Felinska Eleni Amelia , Fuchs Thomas Ewald , Kogkas Alexandros , Chen Zi-Wei , Otto Benjamin , Kowalewski Karl-Friedrich , Petersen Jens , Müller-Stich Beat Peter , Mylonas George , Nickel Felix 
Published: January 2023

Abstract
Background
In minimally invasive surgery (MIS), trainees need to learn how to interpret the operative field displayed on the laparoscopic screen. Experts currently guide trainees mainly verbally during laparoscopic procedures. A newly developed telestration system with augmented reality (iSurgeon) allows the instructor to display hand gestures in real-time on the laparoscopic screen in augmented reality to provide visual expert guidance (telestration). This study analysed the effect of telestration guided instructions on gaze behaviour during MIS training.

Methods
In a randomized-controlled crossover study, 40 MIS naive medical students performed 8 laparoscopic tasks with telestration or with verbal instructions only. Pupil Core eye-tracking glasses were used to capture the instructor’s and trainees’ gazes. Gaze behaviour measures for tasks 1–7 were gaze latency, gaze convergence and collaborative gaze convergence. Performance measures included the number of errors in tasks 1–7 and trainee’s ratings in structured and standardized performance scores in task 8 (ex vivo porcine laparoscopic cholecystectomy).

Results
There was a significant improvement 1–7 on gaze latency [F(1,39) = 762.5, p < 0.01, ηp2 = 0.95], gaze convergence [F(1,39) = 482.8, p < 0.01, ηp2 = 0.93] and collaborative gaze convergence [F(1,39) = 408.4, p < 0.01, ηp2 = 0.91] upon instruction with iSurgeon. The number of errors was significantly lower in tasks 1–7 (0.18 ± 0.56 vs. 1.94 ± 1.80, p < 0.01) and the score ratings for laparoscopic cholecystectomy were significantly higher with telestration (global OSATS: 29 ± 2.5 vs. 25 ± 5.5, p < 0.01; task-specific OSATS: 60 ± 3 vs. 50 ± 6, p < 0.01).

Conclusions
Telestration with augmented reality successfully improved surgical performance. The trainee’s gaze behaviour was improved by reducing the time from instruction to fixation on targets and leading to a higher convergence of the instructor’s and the trainee’s gazes. Also, the convergence of trainee’s gaze and target areas increased with telestration. This confirms augmented reality-based telestration works by means of gaze guidance in MIS and could be used to improve training outcomes.
Approximation of simplicial complexes using matroids and rough sets
Authors: El Atik Abd El Fattah 
Published: January 2023

AbstractMatroid models are used to approximate complex systems that can be used to solve problems in the real world. The main goal of this paper is to show how matrices and rough sets on simplicial complexes can be used to create new types of matroids called simplicial matroids. We will look at some of their material properties. Because of these results, we are interested in learning about circuit and base axioms, rank functions, and closure operators. We also give more equivalent relations that can be used to make other equivalent simplicial matroids, such as 2-circuit simplicial matroids.
Anxiety and behavioral changes in Japanese patients with inflammatory bowel disease due to COVID-19 pandemic: a national survey
Authors: Nakase Hiroshi , Wagatsuma Kohei , Nojima Masanori , Matsumoto Takayuki , Matsuura Minoru , Iijima Hideki , Matsuoka Katsuyoshi , Ohmiya Naoki , Ishihara Shunji , Hirai Fumihito , Takeuchi Ken , Tamura Satoshi , Kinjo Fukunori , Ueno Nobuhiro , Naganuma Makoto , Watanabe Kenji , Moroi Rintaro , Nishimata Nobuaki , Motoya Satoshi , Kurahara Koichi , Takahashi Sakuma , Maemoto Atsuo , Sakuraba Hirotake , Saruta Masayuki , Tominaga Keiichi , Hisabe Takashi , Tanaka Hiroki , Terai Shuji , Hiraoka Sakiko , Takedomi Hironobu , Narimatsu Kazuyuki , Endo Katsuya , Nakamura Masanao , Hisamatsu Tadakazu 
Published: January 2023

Abstract
Background
Given the increasing health concerns for patients with inflammatory bowel disease (IBD), amidst the COVID-19 pandemic, we investigated the impact of the pandemic on the anxiety and behavioral changes in Japanese patients with IBD.

Methods
We analyzed 3032 questionnaires from patients with IBD, aged 16 years or older visiting 30 hospitals and 1 clinic between March 2020 and June 2021. The primary outcome was the score of the anxiety experienced by patients with IBD during the pandemic.

Results
Participants reported a median age of 44 years; 43.3% of the patients were women. Moreover, 60.6% and 39.4% were diagnosed with ulcerative colitis and Crohn’s disease, respectively, with a median disease duration of 10 years. Participants indicated an average of disease-related anxiety score of 5.1 ± 2.5 on a ten-point scale, with a tendency to increase, 1 month after the number of infected persons per population increased. The top three causes for anxiety were the risk of contracting COVID-19 during hospital visits, SARS-CoV-2 infection due to IBD, and infection by IBD medication. Factors associated with anxiety were gender (women), being a homemaker, hospital visit timings, mode of transportation (train), use of immunosuppressive drugs, and nutritional therapy. Most patients continued attending their scheduled hospital visits, taking their medications, experienced the need for a family doctor, and sought guidance and information regarding COVID-19 from primary doctors, television, and Internet news.

Conclusions
Patients with IBD experienced moderate disease-related anxiety due to the pandemic and should be proactively informed about infectious diseases to relieve their anxiety.
Platelet-rich fibrin vs. buccal advancement flap for closure of oroantral communications: a prospective clinical study
Authors: Hunger Stefan , Krennmair Stefan , Krennmair Gerald , Otto Sven , Postl Lukas , Nadalini Danilo-Marc 
Published: January 2023

AbstractObjectivesThe primary aim was to evaluate the success of the defect closure (tight or open) of oroantral communications (OAC) after treatment with platelet-rich fibrin (PRF) clots or a buccal advancement flap (BAF). Secondary outcome measurements were the evaluation of the wound healing, the displacement of the mucogingival border (MGB), and the pain level.Material and methodsFifty eligible patients with an OAC defect larger than 3 mm were randomly assigned to either PRF (test group,n = 25) or BAF (control group,n = 25) for defect closure. In a prospective follow-up program of 21 days, the defect closure healing process, the wound healing course using Landry’s wound healing index (score: 0–5), the displacement of the MGB, and the postoperative pain score were evaluated.ResultsFive patients in each group were lost to follow-up resulting in 40 patients (20 in each group) for continuous evaluation. On postoperative day 21 (study endpoint), no difference regarding success rate (defined as closure of OAC) was noticed between the test (90%; 18/20) and control group (90%; 18/20). A univariate analysis showed significant differences for age and defect size/height for the use of PRF between successful-tight and open–failed defect healing. At the final evaluation, a significantly (p = 0.005) better wound healing score, a lower displacement of the MGB as well as lower pain-score were seen for the use of PRF.ConclusionsBased on the findings of the current study, the use of platelet-rich fibrin represents a reliable and successful method for closure of oroantral communications. The use of PRF clots for defect filling is associated with lowered pain levels and less displacement of the mucogingival border.Clinical relevanceThe defect size should be taken into account when choosing the number and size of PRF plugs.
Coping Strategies and Symptoms of Mental Health Disorders Among People with HIV Initiating HIV Care in Cameroon
Authors: Parcesepe Angela M. , Filiatreau Lindsey M. , Gomez Amanda , Ebasone Peter Vanes , Dzudie Anastase , Pence Brian W. , Wainberg Milton , Yotebieng Marcel , Anastos Kathryn , Pefura-Yone Eric , Nsame Denis , Ajeh Rogers , Nash Denis 
Published: January 2023

AbstractLittle is known about the coping strategies used among people with HIV (PWH), especially in sub-Saharan Africa, and the extent to which adaptive or maladaptive coping strategies are associated with symptoms of mental health disorders. We interviewed 426 PWH initiating HIV care in Cameroon and reported the prevalence of adaptive and maladaptive coping strategies, overall and by presence of symptoms of depression, anxiety, and PTSD. Log binominal regression was used to estimate the association between each type of coping strategy (adaptive or maladaptive) and symptoms of each mental health disorder, separately. Adaptive and maladaptive coping strategies were commonly reported among PWH enrolling in HIV care in Cameroon. Across all mental health disorders assessed, greater maladaptive coping was associated with higher prevalence of depression, anxiety, and PTSD. Adaptive coping was not associated with symptoms of any of the mental health disorders assessed in bivariate or multivariable models. Our study found that PWH endorsed a range of concurrent adaptive and maladaptive coping strategies. Future efforts should explore the extent to which coping strategies change throughout the HIV care continuum. Interventions to reduce maladaptive coping have the potential to improve the mental health of PWH in Cameroon.
Effects of noise on the accuracy of plasma bulk parameters derived from velocity moments of in-situ observations
Authors: Nicolaou Georgios 
Published: January 2023

AbstractWe expose and quantify the inaccuracies of plasma bulk parameters derived from the calculation of velocity moments of noisyin-situplasma observations. First, we simulate typical solar wind proton plasma observations, obtained by a typical top-hat electrostatic analyzer instrument. We add background noise to the simulated observations and analyze them by applying standard methods to derive the plasma density, speed, and temperature. We then compare the analysis results with the parameters we use to simulate the observations in the first place, in order to quantify the inaccuracies in the calculated plasma parameters as functions of the noise level in the observations. We find that even noise levels that are smaller than 1% of the signal peak, lead to significant inaccuracies in some plasma parameters. The plasma temperature suffers the biggest inaccuracies and the plasma speed the smallest. Our results highlight the importance of removing noise from observations when calculating the moments of the constructed plasma distributions. We finally, evaluate one simple method to remove uniform background noise automatically from measurements, which is useful for future on-board analyses.
Standardized butterfly surveys: comparing transect counts and area-time counts in insect monitoring
Authors: Barkmann Friederike , Huemer Peter , Tappeiner Ulrike , Tasser Erich , Rüdisser Johannes 
Published: January 2023

AbstractThe observed insect decline, which threatens agricultural productivity and ecosystem stability, calls for comprehensive international insect monitoring. Monitoring implementation demands standardisation and the integration of new and innovative methods. Therefore, we compared two quantitative butterfly survey methods – the commonly applied transect counts (or ‘Pollard walks’) and more extensive area-time counts. We evaluated the influence of the two methods on the estimation of biodiversity variables such as species richness and species abundance to examine whether they could be applied alternatively for the calculation of butterfly trend indicators. During 576 surveys we conducted 5-minute transect counts and 25-minute area-time counts simultaneously at 144 different sites in Western Austria. The estimated relative butterfly abundance of the two methods for 119 observed species showed a strong linear relationship. While we found 2.4 times more species per site with the more extensive area-time counts than with the transect counts, we also observed a strong correlation between estimates of local abundance (Pearson’s r = 0.85) and observed species richness (Pearson’s r = 0.81) based on the two methods. Area-time counts provide thorough assessments on a given location, enabling a close connection to specific habitat types and facilitating comparability with other plot-based biodiversity assessments. They are more suitable than transect counts when aiming to analyse the drivers of temporal and spatial variability in butterfly occurrence. Furthermore, area-time counts can be used synergistically for the calculation of international butterfly abundance trends (e.g., European butterfly indicators), as we found strong linear relationships for all applied indicators with both methods.
Interaction between extrinsic and intrinsic online review cues: perspectives from cue utilization theory
Authors: Kakaria Shobhit , Simonetti Aline , Bigne Enrique 
Published: January 2023

AbstractWe examine the interaction effects of linguistic style and verification of online reviews in terms of their valence on purchase intention for search and experiential products. We adopt the cue utilization framework to examine the interplay between the extrinsic cues of online reviews—content style (general versus specific), verified purchase (VP) badge (present versus absent), and valence (positive versus negative)—in two product categories—search product (tablet) and experiential product (trip package)—using an experimental design. The findings of the frequentist and Bayesian analyses show that valence supersedes other attributes’ impacts on purchase intention in both product categories. Variations in the content style of the reviews have minor influences on purchase intention. The presence of a VP badge on a review has a negligible influence on purchase intention across both product categories. Valence-content style and valence-VP badge interactions significantly affect purchase intention. Based on these findings, implications are discussed.