bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heliocentric distance dependence of zodiacal light observed by Hayabusa2#
Authors: Tsumura Kohji , Matsuura Shuji , Sano Kei , Iwata Takahiro , Yano Hajime , Kitazato Kohei , Takimoto Kohji , Yamada Manabu , Morota Tomokatsu , Kouyama Toru , Hayakawa Masahiko , Yokota Yasuhiro , Tatsumi Eri , Matsuoka Moe , Sakatani Naoya , Honda Rie , Kameda Shingo , Suzuki Hidehiko , Cho Yuichiro , Yoshioka Kazuo , Ogawa Kazunori , Shirai Kei , Sawada Hirotaka , Sugita Seiji 
Published: August 2023

AbstractZodiacal light (ZL) is sunlight scattered by interplanetary dust particles (IDPs) at optical wavelengths. The spatial distribution of IDPs in the Solar System may hold an important key to understanding the evolution of the Solar System and material transportation within it. The number density of IDPs can be expressed as $$n(r) \sim r^{-\alpha }$$

n

(
r
)

∼

r

-
α

, and the exponent $$\alpha \sim 1.3$$

α
∼
1.3

was obtained by previous observations from interplanetary space by Helios 1/2 and Pioneer 10/11 in the 1970s and 1980s. However, no direct measurements of $$\alpha $$
α
based on ZL observations from interplanetary space outside Earth’s orbit have been performed since then. Here, we introduce initial results for the radial profile of the ZL at optical wavelengths observed over the range 0.76$$-$$
-
1.06 au by ONC-T aboard the Hayabusa2# mission in 2021-2022. The ZL brightness we obtained is well reproduced by a model brightness, although there is a small excess of the observed ZL brightness over the model brightness at around 0.9 au. The radial power-law index we obtained is $$\alpha = 1.30 \pm 0.08$$

α
=
1.30
±
0.08

, which is consistent with previous results based on ZL observations. The dominant source of uncertainty arises from the uncertainty in estimating the diffuse Galactic light (DGL).
Graphical Abstract
Management of chronic and neuropathic pain—journey mapping in Egypt
Authors: Khaled Sherif Ahmed Radwan , Nasef Nasef Mohamed , Arifeen Shams , Youssef Mina , Nessim Sameh , Yazicioğlu Mehmet Cüneyt 
Published: August 2023

Abstract
Background
Epidemiological studies on the prevalence and management of chronic low back pain (CLBP), osteoarthritis (OA), and diabetic peripheral neuropathy (DPN) are limited in Egypt. This review aimed to map and identify data gaps in the patient journey touchpoints for CLBP, OA, and DPN.

Main body of the abstract
An evidence-based mapping approach using MEDLINE, Embase, and Biosis databases were used to identify records between January 2010 and December 2019. Quantitative data synthesis was performed using simple mean or weighted mean, whereas qualitative information was synthesized using a narrative summary. For CLBP, of the 79 records retrieved, 11 were eligible for final analysis (7 CLBP and 4 OA records), and for DPN, of 42 records identified, 13 studies were eligible. For CLBP, data available for prevalence, awareness, and treatment were 34.3%, 39.5%, and 70.0%, respectively. The prevalence of OA was 43.0%. The majority (98.6%) of patients with OA adhered to the treatment, and in 96.2% of the patients’ symptoms were controlled. The prevalence of DPN was estimated to be 42.7%, synthesized evidence indicated that 14.1% of patients were aware of DPN and 22.7% underwent screening.

Conclusion
As the existing literature is limited, further evidence-based studies are required to accurately understand the complexity of patient journey touchpoints in Egypt. Although the studies on musculoskeletal chronic pain syndrome are limited, the high prevalence of chronic low back pain, osteoarthritis and peripheral neuropathy should urge the health care system to organize the research groups and health care facilities to focus on these disorders and to consider them in the global health care plans.
Simulation of CuO-water nanofluid natural convection in a U-shaped enclosure with a T-shaped baffle
Authors: Zemani Farah , Ladjedel Omar , Sabeur Amina 
Published: August 2023

AbstractThe effect of aspect ratio and baffle shape on natural convection patterns in a U-shaped cavity filled with CuO water-based nanofluid is examined in detail, with a T-shaped baffle attached to the cold wall. To solve the coupled continuity, momentum, and energy equations, a finite volume method is used, and the pressure–velocity coupling is iteratively solved with the SIMPLE algorithm. The study investigates the impact of Rayleigh number (104–106), cavity aspect ratio (Ar = 0.4, 0.6), and nanoparticle volume fraction (0 ≤ ϕ ≤ 0.05) on flow pattern and heat transfer features. The results are presented graphically in the form of streamlines, isotherms, mean, and local Nusselt numbers. It is observed that the mean Nusselt number increases with an increase in Rayleigh number, nanoparticle volume fraction, and aspect ratio, resulting in an improvement in heat transfer. The T-shaped baffle enhances heat transfer compared to other baffles. Though changing the aspect ratio (0.4 ≤ Ar ≤ 0.6) does not alter the flow pattern, an increase in Ar leads to an enhancement in the heat transfer rate.
Folic acid prescription and suicide attempt prevention: effect of past suicidal behaviour, psychiatric diagnosis and psychotropic medication
Authors: Mann J. John , Hur Kwan , Lavigne Jill E. , Gibbons Robert D. 
Published: August 2023

Summary
We previously showed that folic acid prescriptions for any indication were associated with lower rates of suicidal behaviour. Given that future randomised clinical trials are likely to focus on psychiatric disorders carrying elevated risk for suicide, we now report on the moderating effects of prior suicidal behaviour, psychiatric diagnoses and psychotropic medications on potential antisuicidal effects of folic acid. Data were obtained from the MarketScan Commercial Claims and Encounters databases that cover 164 million insured persons from 2005–2017, from which a cohort of 866 586 patients was derived. Analysis revealed no significant moderation effects on the antisuicidal effect of folic acid. These findings indicate that the potential benefit of folic acid for preventing suicidal behaviour is comparable in psychiatric populations at higher risk of suicide and that it may be additive to any benefit from psychotropic medications.
CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity
Authors: Ford Matthew J. , Harwalkar Keerthana , Kazemdarvish Hengameh , Yamanaka Nobuko , Yamanaka Yojiro 
Published: August 2023

ABSTRACT
The epithelium lining the oviduct or fallopian tube consists of multiciliated and secretory cells, which support fertilization and preimplantation development, however, its homeostasis remains poorly understood. CD133/Prom1 expression has been used as a marker to identify adult stem cell populations in various organs and often associated with cancer cells that have stem-like properties. Using an antibody targeted to CD133 and a Cre recombinase-based lineage tracing strategy, we found that CD133/Prom1 expression is not associated with a stem/progenitor population in the oviduct but marked predominantly multiciliated cells with a low generative capacity. Additionally, we have shown that CD133 is disparately localised along the oviduct during neonatal development, and that Prom1 expressing secretory cells in the ampulla rapidly transitioned to multiciliated cells and progressively migrated to the ridge of epithelial folds.
Effects of particle size and thickness of quartz sand on the webbed foot kinematics of mallard (Anas platyrhynchos)
Authors: Han Dianlei , Liu Hairui , Hu Jinrui , Yang Qizhi 
Published: August 2023

ABSTRACT
The webbed foot structure of mallards (Anas platyrhynchos) exhibits effective anti-subsidence properties when walking on soft ground. To investigate the effects of quartz sand particle size and thickness on joint angles and the movement patterns of webbed feet, we created a testing substrate with quartz sand and utilized high-speed cameras and kinematic analysis tools for data acquisition. Mallards mainly adjusted the tarsometatarso-phalangeal joint (TMTPJ) during touch-down and lift-off stages in response to increasing particle size or enhanced ground roughness. Conversely, adjustments to the intertarsal joint (ITJ) predominantly took place during mid-stance. Conversely, mallards predominantly adjusted the ITJ during touch-down and lift-off when coping with increased quartz sand thickness, with TMTPJ adjustments mainly occurring at touch-down. As quartz sand particle size increased, the TMTPJ angle increased, the ITJ angle decreased, toe closure advanced, and the duty factor decreased throughout the entire stride cycle. In contrast, increasing quartz sand thickness led to more delayed TMTPJ adjustments, slower webbed foot closure, and an increased duty factor throughout the stride cycle. Mallards modify their leg posture to notably decrease the touch-down foot angle upon encountering sandy terrain. This action subsequently forms a depression beneath their feet, contributing to sand consolidation and limiting flow. During the stance phase, the mallard's weight is distributed across the webbed foot, generating minimal pressure and preventing significant subsidence while walking on sandy ground.
Ageism and Its Impact on Quality of Life Among Older Persons Experiencing Difficulties with Activities of Daily Living
Authors: Sandoval Garrido Felipe Alfonso , Bolt Timothy , Taniguchi Yuta , Lloyd-Sherlock Peter 
Published: August 2023

Background: As the number of older persons increases globally, so does ageism, or being discriminated against because of their age. The overlap between ageism and ableism, which is discrimination based on impairments or disability may put persons having difficulties with their basic (ADL) or instrumental activities of daily living (IADL) at a higher risk of discrimination. Discrimination leads to poorer quality of life. However, ageism remains understudied, particularly in the UK. Methods: Data from the English Longitudinal Study of Ageing (ELSA) collected in the 2010-2011 period (Wave 5) was used to assess ageism, ADL/IADL status, and quality of life (CASP-19) at baseline. Multivariable linear regression was used to estimate the changes in the quality of life while adjusting for covariates and their baseline values in two following periods: 2016-2017 (Wave 7) and 2018-2019 (Wave 9). Results: At baseline, quality-of-life scores were significantly lower among individuals dealing with difficulties (33.6 points) compared to those without them (41.5 points), with a difference of 7.9 points (p < .001). In the following waves, age discrimination was found to have a negative effect on the quality of life of all the participants regardless of ADL/IADL difficulties (B: -1.106, p=<0.001), and also among those without difficulties (B=-1.401, p=<0.001). However, among those with difficulties, no such association was found in any of the analyses. Conclusions: Discrimination has a detrimental effect on quality of life, but this effect may be mediated by characteristics of the older persons suffering from loss of independence, such as coping mechanisms, resilience, social support, personality, and other latent characteristics that may be associated with ADL/IADL difficulties not included in this study. These findings underscore the importance of understanding the driving elements of quality of life among older persons to effectively inform future intervention strategies, especially for those at risk of ageism.
Auditing cesarean section indications in women of Groups 1 to 4 of Robson's Ten-Group Classification System: A descriptive study at a university hospital in Thailand
Authors: Witsawapaisan Waratchaya , Komwilaisak Ratana , Sothornwit Jen , Kongwattanaku Kiattisak , Jampathong Nampet , Dumont Alexander , Pilar Betrán Ana , Robson Michael , Duangkum Chatuporn , Saksiriwuttho Piyamas , Chaiyarach Sukanya , Lumbigano Pisake 
Published: August 2023

Aim: To determine the appropriateness of indication for cesarean section in women at term with a single fetus in cephalic presentation without previous CS irrespective of parity and how labor started (Robson's Ten-Group Classification System [RTGCS] groups 1-4). Methods: This was a descriptive study assessing medical records of 311 women in RTGCS groups 1- 4, between 1st January 2020 and 31st December 2020 who underwent a CS in Srinagarind Hospital, a university hospital, Khon Kaen, Thailand. Appropriateness of CS indications was assessed using criteria developed by our institute. Indications were classified into three categories: cephalopelvic disproportion (CPD), fetal indications, and other maternal indications. Results: The overall appropriate rate of CS indications in RTGCS groups 1-4 was 32.5% (95% CI 26.8% – 38.7%). The appropriate rates of CS indications in RTCGS group 1, 2a, 2b, 3, 4a, and 4b were 43.0% (95% CI 35.2% - 51.2%), 10.6% (95% CI 0.0% - 24.9%), 11.7% (95% CI 0.0% - 25.0%), 50.0% (95% CI 32.1% - 68.6%), 0% (95% CI 0.0% - 100%), and 40.0% (95% CI 20.0% - 74.8%) respectively. Conclusion: Low appropriateness in CS indications in RTGCS groups 1-4 leads to high CS rates. Increasing appropriateness of CS indications in this population will reduce unnecessary CS. Interventions focusing on increasing appropriateness in CS indications are urgently required to achieve appropriate use of CS.
The impact of childbirth on women's sexuality and methods of treating its disorders
Authors: Matkowski Igor , Bigos Paula , Dendys Konrad , Bieniasz Jan , Kuźnicki Wojciech , Potyrała Piotr 
Published: August 2023

Postpartum sexual disorders can significantly impact individuals and their partner relationships, affecting a considerable percentage of women, with reduced libido being the most common symptom. Factors such as breastfeeding, postpartum depression, and communication issues with partners increase the risk of experiencing these disorders.
This review aimed to explore scientific reports on the frequency, contributing factors, and treatment options for postpartum sexual disorders. The analysis was conducted by reviewing literature available in PubMed.
The mode of delivery (natural or cesarean) does not significantly differ in its impact on postpartum sexual disorders.
Non-pharmacological treatments encompass psychotherapy, from which mindfulness-based cognitive is the most effective and physical exercises. Engaging in regular physical exercises contributes to enhanced sexual experiences, notably in terms of sexual arousal and offers other health benefits. Moreover, Kegel exercises have been demonstrated as a method to increase sexual satisfaction.
Medications used to treat libido dysfunction include flibanserin, bremelanotide, and bupropion. For women experiencing depression and sexual dysfunction, antidepressants with a lesser impact on sexual function may be considered.
Vaginal dryness can be effectively addressed with moisturizing gels, globules, and lubricants.
When considering pharmacotherapy, it is essential to evaluate the severity of symptoms, potential side effects for both the woman and her child being breastfed, and psychological discomfort. Physicians play a vital role, as women with sexual disorders may find it challenging to express their concerns. Partner support is crucial in improving a woman's sexual life.
D-Optimal Data Fusion: Exact and Approximation Algorithms
Authors: Li Yongchun , Fampa Marcia , Lee Jon , Qiu Feng , Xie Weijun , Yao Rui 
Published: August 2023

We study the D-optimal Data Fusion (DDF) problem, which aims to select new data points, given an existing Fisher information matrix, so as to maximize the logarithm of the determinant of the overall Fisher information matrix. We show that the DDF problem is NP-hard and has no constant-factor polynomial-time approximation algorithm unless P = NP. Therefore, to solve the DDF problem effectively, we propose two convex integer-programming formulations and investigate their corresponding complementary and Lagrangian-dual problems. Leveraging the concavity of the objective functions in the two proposed convex integer-programming formulations, we design an exact algorithm, aimed at solving the DDF problem to optimality. We further derive a family of submodular valid inequalities and optimality cuts, which can significantly enhance the algorithm performance. We also develop scalable randomized-sampling and local-search algorithms with provable performance guarantees. Finally, we test our algorithms using real-world data on the new phasor-measurement-units placement problem for modern power grids, considering the existing conventional sensors. Our numerical study demonstrates the efficiency of our exact algorithm and the scalability and high-quality outputs of our approximation algorithms. History: Accepted by Andrea Lodi, Area Editor for Design & Analysis of Algorithms—Discrete. Funding: Y. Li and W. Xie were supported in part by Division of Civil, Mechanical and Manufacturing Innovation [Grant 2046414] and Division of Computing and Communication Foundations [Grant 2246417]. J. Lee was supported in part by Air Force Office of Scientific Research [Grants FA9550-19-1-0175 and FA9550-22-1-0172]. M. Fampa was supported in part by Conselho Nacional de Desenvolvimento Científico e Tecnológico [Grants 305444/2019-0 and 434683/2018-3]. F. Qiu and R. Yao were supported in part by the U.S. Department of Energy Advanced Grid Modeling Program under [Grant DE-OE0000875]. Supplemental Material: The e-companion is available at https://doi.org/10.1287/ijoc.2022.0235 .
Identifying the Bottleneck Unit: Impact of Congestion Spillover in Hospital Inpatient Unit Network
Authors: Kim Song-Hee , Zheng Fanyin , Brown Joan 
Published: August 2023

Because a hospital is an interconnected, interdependent network of care units, allocating resources—beds, nurses, and improvement initiatives—to one unit to reduce its congestion may have spillover effects on other units. If such congestion spillover is substantial, ignoring it may lead to unintended consequences and missed opportunities. We use data collected over five years from a hospital with 16 inpatient units to empirically examine whether and how much congestion propagates through the network of inpatient units. Our estimation result suggests that the magnitude of the congestion spillover is indeed substantial in our study hospital. For example, increasing one inpatient unit’s utilization by 10 percentage points today can increase its neighboring inpatient unit’s utilization by up to 4.33 percentage points tomorrow. Using counterfactual analyses, we estimate the effect of adding a bed to each unit. We find that due to congestion spillover, adding one bed to the bottleneck unit can free up 4.14 beds in the hospital, which translates to 383.53 more hospital visits per year or a 3% increase in hospital throughput. This effect is about three times bigger in magnitude compared with what one can achieve by naively choosing which unit to add a bed to. Hospitals and other manufacturing and service systems with complex interdependence across resources can use our empirical framework to examine the spillover effect of resources on performance metrics and leverage such understanding to effectively improve their operations. This paper was accepted by Vishal Gaur, operations management. Funding: This work was supported by the Creative-Pioneering Researchers Program through Seoul National University. Supplemental Material: The data files and online appendices are available at https://doi.org/10.1287/mnsc.2023.4887 .
Knockdown resistance mutations are common and widely distributed in Xenopsylla cheopis fleas that transmit plague in Madagascar
Authors: Hutton Shelby M. , Miarinjara Adelaide , Stone Nathan E. , Raharimalala Fara N. , Raveloson Annick O. , Rakotobe Harimanana Ravo , Harimalala Mireille , Rahelinirina Soanandrasana , McDonough Ryelan F. , Ames Abbe D. , Hepp Crystal , Rajerison Minoarisoa , Busch Joseph D. , Wagner David M. , Girod Romain 
Published: August 2023

BackgroundPlague, caused by the bacteriumYersinia pestis, remains an important disease in Madagascar, where the oriental rat flea,Xenopsylla cheopis, is a primary vector. To control fleas, synthetic pyrethroids (SPs) have been used for >20 years, resulting in resistance in manyX.cheopispopulations. The most common mechanisms of SP resistance are target site mutations in the voltage-gated sodium channel (VGSC) gene.Methodology/Principal findingsWe obtained 25 collections ofX.cheopisfrom 22 locations across Madagascar and performed phenotypic tests to determine resistance to deltamethrin, permethrin, and/or dichlorodiphenyltrichloroethane (DDT). Most populations were resistant to all these insecticides. We sequenced a 535 bp segment of the VGSC gene and identified two different mutations encoding distinct substitutions at amino acid position 1014, which is associated with knockdown resistance (kdr) to SPs in insects.Kdrmutation L1014F occurred in all 25 collections; a rarer mutation, L1014H, was found in 12 collections. There was a significant positive relationship between the frequency ofkdralleles and the proportion of individuals surviving exposure to deltamethrin. Phylogenetic comparisons of 12 VGSC alleles in Madagascar suggested resistant alleles arose from susceptible lineages at least three times. Because genotype can reasonably predict resistance phenotype, we developed a TaqMan PCR assay for the rapid detection ofkdrresistance alleles.Conclusions/SignificanceOur study provides new insights into VGSC mutations in Malagasy populations ofX.cheopisand is the first to report a positive correlation between VGSC genotypes and SP resistance phenotypes in fleas. Widespread occurrence of these two SP resistance mutations inX.cheopispopulations in Madagascar reduces the viability of these insecticides for flea control. However, the TaqMan assay described here facilitates rapid detection ofkdrmutations to inform when use of these insecticides is still warranted to reduce transmission of plague.