bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and Properties of a Novel Thermally Conductive Pressure‐Sensitive Adhesive with UV‐Responsive Peelability
Authors: Cui Xiaohua , Liu Jiaming , Zhang Ending , Gong Ziyang , Liang Liyan , Shi Jun , Hao Xiaopeng , Hu Jiwen , Lu Mangeng 
Published: February 2023

AbstractThermally conductive pressure‐sensitive adhesive (PSA) has received a great amount of attention in recent years, but the traditional PSA hardly loses adhesion properties after UV irradiation or heating. Therefore, endowing thermally conductive adhesive with UV‐responsive peelability becomes a design strategy. Herein, vinyl‐functionalized graphene (AA‐GMA‐G) is prepared by modifying graphene with acrylic acid and subsequently reacting with glycidyl methacrylate. Then, the UV‐curable acrylate copolymer is synthesized by grafting glycidyl methacrylate. Finally, the novel thermally conductivity PSA with UV‐responsive peelability is obtained by blending the copolymer with AA‐GMA‐G and photoinitiator. The results show that the PSA at 2 wt% AA‐GMA‐G loading exhibits an excellent thermal conductivity (0.74 W m−1 K−1) and a relatively strong peel strength, increasing by 15% compared with pristine graphene/PSA. Interestingly, the peel strength of AA‐GMA‐G/PSA can achieve a dramatic drop after UV treatment, and the decrease rate is 96.7%. Therefore, the novel thermally conductive PSA with UV‐responsive peelability has potential applications in certain electronic devices.
Crosslinked and Multi‐Responsive Polymeric Vesicles as a Platform to Study Enzyme‐Mediated Undocking Behavior: Toward Future Artificial Organelle Communication
Authors: Wang Dishi , Moreno Silvia , Boye Susanne , Voit Brigitte , Appelhans Dietmar 
Published: February 2023

AbstractVarious cellular functions are successfully mimicked, opening the door to the next generation of therapeutic approaches and systems biology. Herein, the first steps are taken toward the construction of artificial organelles for mimicking cell communication by docking and undocking of cargo in the membrane of swollen artificial organelles. Stimuli‐responsive and crosslinked polymeric vesicles are used to allow docking processes at acidic pH at which ferrocene units in the swollen membrane state can undergo desired specific host–guest interaction using β‐cyclodextrin as model cargo. The release of the cargo mediated by two different enzymes, glucose oxidase and α‐amylase, is investigated, triggered by distinct enzymatic undocking mechanisms. Different release times for a useful transport are shown that can be adapted to different communication pathways. In addition, Förster resonance energy transfer (FRET) experiments further support the hypotheses of host–guest inclusion complexation formation and their time‐dependent breakdown. This work paves a way to a platform based on polymeric vesicles for synthetic biology, cell functions mimicking, and the construction of multifunctional cargo delivery system.
Effects of safe handling education on cognition, compliance and stress handling of antineoplastic drugs in clinical nurses
Authors: Jun Eun‐Mi , Kang Se‐Won 
Published: February 2023

AbstractTo evaluate the effects of safe‐handling education on the cognition, practice and stress handling of antineoplastic drugs in clinical nurses. This study uses a quasi‐experimental, non‐equivalent control group pre‐test and post‐test design. The experimental and control groups had 30 nurses each, who handled antineoplastic drugs from three institutions. This study examines the safe handling of antineoplastic drugs six times, for two hours each over two weeks. To verify the homogeneity of the experimental and control groups and the effectiveness of safe‐handling education about antineoplastic drugs, a chi‐square test and independent samples t‐test were performed. The results were statistically significant in both groups (cognition [t = 6.84, p < 0.001], practice [t = 5.86, p < 0.001], and the stress of handling antineoplastic drugs [t = 5.15, p < 0.001]). Education on ways to safely handle antineoplastic drugs improves cognition, practice and stress handling of these drugs; moreover, proper education minimizes exposure.
Synthesis, characterization, and applications of cobalt bismuth layered double hydroxide nanoparticles: Physical insights towards a potential material as fuel additive and photocatalyst
Authors: Jamil Saba , Alvi Afaaf Rahat , Bibi Shamsa , Jahan Nazish , Naqvi Syed Ali Raza , Khan Shanza Rauf , Zia Khalid Mahmood , Janjua Muhammad Ramzan Saeed Ashraf 
Published: February 2023

AbstractIn present research, novel cobalt bismuth layered double hydroxides (Co/Bi‐LDHs) were fabricated by urea hydrolysis approach at laboratory scale in mixed solvent of water and ethylene glycol. Synthesized product was analyzed by different techniques such as powder X‐ray diffraction (PXRD), scanning electron microscopy (SEM), and Fourier transmission infrared spectroscopy (FTIR). Cobalt oxide (Co3O4) was obtained after calcinations in nanometer range, which showed excellent catalytic characteristics. Calcined LDHs were used as photocatalyst to degrade Congo Red (CR) under different conditions of catalyst and hydrogen peroxide. Different parameters such as flash point, fire point, cloud point, pour point, kinematic viscosity, and specific gravity were also studied in order to check the efficiency of commercial diesel at different concentrations of catalyst.
Predicting binding affinity changes from long‐distance mutations using molecular dynamics simulations and Rosetta
Authors: Wells Nicholas G. M. , Smith Colin A. 
Published: February 2023

AbstractComputationally modeling how mutations affect protein–protein binding not only helps uncover the biophysics of protein interfaces, but also enables the redesign and optimization of protein interactions. Traditional high‐throughput methods for estimating binding free energy changes are currently limited to mutations directly at the interface due to difficulties in accurately modeling how long‐distance mutations propagate their effects through the protein structure. However, the modeling and design of such mutations is of substantial interest as it allows for greater control and flexibility in protein design applications. We have developed a method that combines high‐throughput Rosetta‐based side‐chain optimization with conformational sampling using classical molecular dynamics simulations, finding significant improvements in our ability to accurately predict long‐distance mutational perturbations to protein binding. Our approach uses an analytical framework grounded in alchemical free energy calculations while enabling exploration of a vastly larger sequence space. When comparing to experimental data, we find that our method can predict internal long‐distance mutational perturbations with a level of accuracy similar to that of traditional methods in predicting the effects of mutations at the protein–protein interface. This work represents a new and generalizable approach to optimize protein free energy landscapes for desired biological functions.
Distributed secure balancing control for battery energy storage systems subject to random denial‐of‐service attacks
Authors: Lu Kunjie , Tian Engang , Wang Licheng 
Published: February 2023

SummaryThis paper is concerned with the distributed secure balancing control problem for battery energy storage systems (BESSs) in a Direct Current (DC) microgrid. The Denial‐of‐service (DoS) attacks, which appear in a random way, are taken into account during the data exchange of individual BESS units. By introducing a well‐designed compensation term, an improved distributed consensus algorithm is developed to deal with the state‐of‐charge (SOC) balance issue in the presence of randomly occurring cyber attacks. With the aid of the Lyapunov stability theory, sufficient conditions are established for the networked control system such that the balance of the SOC for each BESS unit is achieved under certain constraints. The effectiveness of the proposed balance scheme is verified by a series of illustrative simulation experiments.
Engineered Cobalt Single‐Atoms@BiFeO3 Heteronanostructures for Highly Efficient Solar Water Oxidation
Authors: Djatoubai Essossimna , Khan Muhammad Shuaib , Haq Sajjad ul , Heidari Golnaz , Dong Chung‐Li , Nga Ta Thi Thuy , Chen Jeng‐Lung , Shen Shaohua 
Published: February 2023

AbstractEfficient charge–carrier separation and their utilization are the key factors in overcoming sluggish four‐electron reaction kinetics involved in photocatalytic oxygen evolution. Here, a novel study demonstrates the significance of Na2S2O8 as a sacrificial agent in comparison to AgNO3. Resultantly, BiFeO3 (BFO) and titanium doped‐oxygen deficient BiFeO3 (Ti‐BFO‐R) nanostructures achieve ≈64 and 44.5 times higher O2 evolution in the presence of Na2S2O8 compared to AgNO3 as a sacrificial agent, respectively. Furthermore, the presence of Co single atoms (Co‐SAs) deposited via immersion method on BFO and Ti‐BFO‐R nanostructures led to achieving outstanding O2 evolution at a rate of 16.11 and 23.89 mmol g−1 h−1, respectively, which is 153 and 227.5 times higher compared to BFO (in the presence of AgNO3), the highest O2 evolution observed for BFO‐based materials to date. The successful deposition of Co‐SAs is confirmed by aberration‐corrected high‐angle annular dark‐field scanning transmission electron microscopy (AC HAADF‐STEM) and X‐ray absorption near‐edge structure (XANES). The charge transfer investigations confirm the significance of Co‐SAs on BFO‐based photocatalysts for improved charge–carrier separation, transport, and utilization. This novel study validates the excellent role of Na2S2O8 as a sacrificial agent and Co‐SAs as a cocatalyst for BFO‐based nanostructures for efficient O2 evolution.
Correction of direction reduction factors of extreme wind speed considering the Ekman spiral in the wind load estimation of super high‐rise buildings with heights of 400–800 m
Authors: He Bin , Quan Yong , Gu Ming , Chen Jialu 
Published: February 2023

SummaryThe wind direction in the atmospheric boundary layer (ABL) twists with height due to the Coriolis force; this phenomenon is called the Ekman spiral. However, this phenomenon is generally not considered in the present wind load estimation of super high‐rise buildings, which may lead to an incorrect estimation and affect the safety of structures. Therefore, this study considers and analyzes the influence of the Ekman spiral phenomenon in the wind direction reduction effect (WDRE) of the wind load of super high‐rise buildings. First, this paper proposes an empirical fitting equation for the twisted wind direction angle for a height of 100–800 m according to the classical Ekman spiral theory model (CE model). Subsequently, on the basis of twisted wind, this paper proposes a method for the correction of the wind direction reduction factors (WDRFs) of strong winds considering the influence of the Ekman spiral phenomenon in the design wind load estimation of super high‐rise buildings with heights of 400–800 m. A high‐frequency balance force measurement test of a square‐section super high‐rise building model was performed to analyze the influence of the Ekman spiral phenomenon on the WDRE of the aerodynamic force and wind‐induced response. Three Chinese cities (i.e., Beijing, Wuhan, and Kunming) are selected as case studies to illustrate the importance and necessity of the correction method. The results demonstrate that the proposed empirical fitting equation accurately determines the twisted wind direction angle at different latitudes and altitudes. Furthermore, estimating the design wind load while considering the WDRE and neglecting the influence of the Ekman spiral phenomenon may lead to a significant underestimation of the wind load of super high‐rise buildings, rendering the designed building structure more dangerous.
The evaluation of the effect of tafluprost on the intraocular pressure of healthy male guinea pigs under different light‐and‐darkness regimes
Authors: Armin Arghavan , Arfaee Farnoosh , Ozmaie Saeed , Asghari Ahmad 
Published: February 2023

AbstractBackgroundOcular hypertension is one of the most underdiagnosed ocular abnormalities among guinea pigs around the world.ObjectivesThe current study investigates the effect of 0.0015% preservative‐free tafluprost ophthalmic solution (Zioptan) on the intraocular pressure of 16 healthy male guinea pigs (Cavia porcellus) under different light/darkness regimes.MethodsAll guinea pigs received a single drop of tafluprost at 5:30 in the right eye, whereas the contralateral eyes served as control to receive a placebo. Then, the animals were randomly divided into two groups; group A was exposed to light, whereas group B was placed in darkness from 5:30 to 18:00. Rebound tonometry (TonoVet) was instrumented to measure IOP values at 5:30 (baseline), 6:00, 7:00, 8:00, 9:00 and then every 3 h until 18:00.ResultsThe maximum IOP reduction associated with tafluprost was observed at 6:00 by −1.4 ± 1.1 mmHg (p‐value = 0.026) and −2.5 ± 1.2 mmHg (p‐value = 0.011) in group A and B, respectively (repeated measure ANOVA test). There was a significant difference between the mean right and left eye IOP values in both groups at 5:30, 6:00, 7:00 and 8:00 (p‐value <0.05), which was greater in amount in group B compared to group A due to the effect of darkness on IOP reduction.ConclusionsIt is suggested that the variations of IOP in different light/dark conditions be taken into consideration when applying ocular hypotensive agents on guinea pigs’ eyes.
Emergence of [GAR+] cells in yeast from sake brewing affects the fermentation properties
Authors: Tanabe Koichi , Maeda Natsumi , Okumura Honoka , Shima Jun 
Published: February 2023

AbstractIn the traditional (kimoto) method of sake (Japanese rice wine) brewing, Saccharomyces cerevisiae yeast cells are exposed to lactate, which is produced by lactic acid bacteria in the seed mash. Lactate promotes the appearance of glucose‐repression‐resistant [GAR+] cells. Herein, we compared the resistance to glucose repression among kimoto, industrial, and laboratory yeast strains. We observed that the frequencies of the spontaneous emergence of [GAR+] cells among the kimoto strains were higher than those among the industrial and laboratory strains. The fermentation ability of a kimoto yeast (strain U44) was lower than that of an industrial strain (K701), as [GAR+] cells generally showed slower ethanol production. The addition of lactate decreased the fermentation abilities of the K701 strain by increasing the number of [GAR+] cells, but it did not affect those of the U44 strain. These results suggest that lactate controlled fermentation by promoting the appearance of [GAR+] cells in the industrial sake strains but not in the kimoto strains.
Improving detection performance of hepatocellular carcinoma and interobserver agreement for liver imaging reporting and data system on CT using deep learning reconstruction
Authors: Okimoto Naomasa , Yasaka Koichiro , Kaiume Masafumi , Kanemaru Noriko , Suzuki Yuichi , Abe Osamu 
Published: February 2023

Abstract
Purpose
This study aimed to compare the hepatocellular carcinoma (HCC) detection performance, interobserver agreement for Liver Imaging Reporting and Data System (LI-RADS) categories, and image quality between deep learning reconstruction (DLR) and conventional hybrid iterative reconstruction (Hybrid IR) in CT.

Methods
This retrospective study included patients who underwent abdominal dynamic contrast-enhanced CT between October 2021 and March 2022. Arterial, portal, and delayed phase images were reconstructed using DLR and Hybrid IR. Two blinded readers independently read the image sets with detecting HCCs, scoring LI-RADS, and evaluating image quality.

Results
A total of 26 patients with HCC (mean age, 73 years ± 12.3) and 23 patients without HCC (mean age, 66 years ± 14.7) were included. The figures of merit (FOM) for the jackknife alternative free-response receiver operating characteristic analysis in detecting HCC averaged for the readers were 0.925 (reader 1, 0.937; reader 2, 0.913) in DLR and 0.878 (reader 1, 0.904; reader 2, 0.851) in Hybrid IR, and the FOM in DLR were significantly higher than that in Hybrid IR (p = 0.038). The interobserver agreement (Cohen’s weighted kappa statistics) for LI-RADS categories was moderate for DLR (0.595; 95% CI, 0.585–0.605) and significantly superior to Hybrid IR (0.568; 95% CI, 0.553–0.582). According to both readers, DLR was significantly superior to Hybrid IR in terms of image quality (p ≤ 0.021).

Conclusion
DLR improved HCC detection, interobserver agreement for LI-RADS categories, and image quality in evaluations of HCC compared to Hybrid IR in abdominal dynamic contrast-enhanced CT.

Graphical Abstract
The archaeobotany of Qaratepe, Azerbaijan 2nd–13th century
Authors: Stone David 
Published: February 2023

AbstractThis paper presents the results of an archaeobotanical analysis of plant macro-remains recovered during excavations of a rural tepe site at Qaratepe, Azerbaijan, occupied during the Sasanian and Islamic periods between the 2nd and 13th centuriesad. The material derives from a 4 year Oxford University expedition which occurred between 2015 and 2018, ‘The Archaeological Exploration of Barda Project (AEB)’, established to investigate the provincial structure of the eastern Caucasus region in the Late Antique and early Islamic periods. Traditionally, archaeological practice in Azerbaijan has not embraced environmental archaeological techniques and despite the region’s importance to the understanding of early agriculture and the diffusion of crop species during the Islamic period, little archaeobotanical research has been conducted there to date. This assemblage therefore forms a rare and unique contribution to the field of archaeobotany in the Late Antique and Islamic periods in Azerbaijan and provides the first archaeobotanical evidence of crop husbandry at a rural settlement during these periods. In total, 8,676 carbonised plant remains representing a minimum of 60 species were recorded from 80 samples analysed, providing important insights into plant utilisation in Azerbaijan (Full taxonomic list available in on-line supplementary material (ESM)). Archaeobotanical evidence has revealed the range of crops cultivated and consumed at the site between the 2nd and 13th centuries. Results demonstrate that naked wheat (Triticum aestivum/durum/turgidum), barley (Hordeum vulgare), and broomcorn millet (Panicum miliaceum) were the primarily cultivated crops between the 2nd and 6th centuries, key crops that have been present in the Southern Caucasus for several millennia. The study has also identified the cultivation of rice (Oryza sativa), watermelon (Citrullus lanatus), and melon (Melo sativa) in the 13th century, indicating a change in agricultural production in the Islamic period and the introduction of several new cultivars and agricultural adaptions.
A mathematically rigorous proof on the decoupling of the plate and disc problem
Authors: Meyer-Coors Michael , Kienzler Reinhold , Schneider Patrick 
Published: February 2023

AbstractThe three-dimensional problem of linear elasticity (linear 3D problem) can be derived from the elastic and dual potential using the calculus of variations and integration by parts in all three dimensions. For the special geometry of a thin cuboid solid, the application of integration by parts only in two dimensions and the use of Taylor series expansions yields the quasi-two-dimensional problem (quasi-2D problem). We show in a mathematically rigorous way that this problem can be separated into the plate and disc subproblem. Further, we prove that the decoupling behaviour of both subproblems depends on the sparsity scheme of the elasticity tensor. As a consequence of our mathematically rigorous proofs, the (decoupled) subproblems are together equivalent to the linear 3D problem. At the end, we discuss the implications of our results based on an example.
Structure and dynamics of old-growth Pinus nigra stands in Southeast Europe
Authors: Nagel Thomas A. , Cerioni Matteo 
Published: February 2023

AbstractPinus nigra has a scattered but widespread distribution across Mediterranean mountain regions, where it has often been planted to restore degraded sites, yet few studies have examined the dynamics of natural P. nigra stands. Old-growth P. nigra stands often occur on precipitous, rugged locations in the Southeastern Alps and Dinaric Mountain range, providing unique opportunities to study their natural dynamics and disturbance history. We quantified the structure and composition and used dendroecological methods to reconstruct disturbance history, including samples of fire-scarred trees, in two old-growth stands located in Slovenia and Bosnia-Herzegovina. The study stands were dominated by P. nigra, but also included a number of other thermophilic tree species, as well as shade-tolerant species common in the surrounding mountain forests. Both sites had an irregular uneven-age structure with several pulses of recruitment, perhaps indicating the influence of past fire events, and P. nigra regeneration was relatively abundant (> 3000 stems ha−1). The most recent fires at each site burned in 1947 and 1969, and there was evidence of post-fire recruitment at the study sites. However, although tree cores sampled from fire-scarred trees suggest there were scattered, but infrequent fires over the past few centuries, we did not find evidence suggesting a regime of frequent recurring surface fires. The results suggest that rare surface fires may play a role in preventing successional replacement of P. nigra on productive sites, whereas steep, rocky sites likely support persistent populations in the absence of fire.
Climate justice in higher education: a proposed paradigm shift towards a transformative role for colleges and universities
Authors: Kinol Alaina , Miller Elijah , Axtell Hannah , Hirschfeld Ilana , Leggett Sophie , Si Yutong , Stephens Jennie C. 
Published: February 2023

AbstractMoving beyond technocratic approaches to climate action, climate justice articulates a paradigm shift in how organizations think about their response to the climate crisis. This paper makes a conceptual contribution by exploring the potential of this paradigm shift in higher education. Through a commitment to advancing transformative climate justice, colleges and universities around the world could realign and redefine their priorities in teaching, research, and community engagement to shape a more just, stable, and healthy future. As inequitable climate vulnerabilities increase, higher education has multiple emerging opportunities to resist, reverse, and repair climate injustices and related socioeconomic and health disparities. Rather than continuing to perpetuate the concentration of wealth and power by promoting climate isolationism’s narrow focus on technological innovation and by prioritizing the financial success of alumni and the institution, colleges and universities have an opportunity to leverage their unique role as powerful anchor institutions to demonstrate climate justice innovations and catalyze social change toward a more equitable, renewable-based future. This paper explores how higher education can advance societal transformation toward climate justice, by teaching climate engagement, supporting impactful justice-centered research, embracing non-extractive hiring and purchasing practices, and integrating community-engaged climate justice innovations across campus operations. Two climate justice frameworks, Green New Deal-type policies and energy democracy, provide structure for reviewing a breadth of proposed transformational climate justice initiatives in higher education.