bluuebunny/crossref_metadata_2025_split huggingface dataset:
La prohibición constitucional de la confiscatoriedad en la denominada “plusvalía municipal”
Authors: Gobierno Local Fundación 
Published: September 2023

El Tribunal Constitucional ha declarado inconstitucionales liquidaciones de plusvalía municipal tanto en situaciones de no concurrencia de incremento de valor (ausencia de hecho imponible) como cuando la cuota tributaria sea igual o superior al incremento (por infracción del principio de no confiscatoriedad).
En relación con cuotas tributarias que absorben todo el aumento de valor producido, el Consejo de Estado anticipó que correspondía al Legislativo determinar qué porcentaje del incremento podía integrar la cuota tributaria del impuesto. Desde luego, no correspondía dicha función al Consejo de Estado.
El Tribunal Supremo, en sentido análogo al parecer del Consejo de Estado, tampoco ha considerado que los tribunales de justicia puedan fijar el importe exigible del impuesto en los casos de que la cuota absorba la totalidad del incremento de valor. En tales supuestos, el tribunal competente solo puede proceder a la anulación de la liquidación practicada.
Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome
Authors: Arellano Buendia Abraham Said , Juárez Rojas Juan Gabriel , García-Arroyo Fernando , Aparicio Trejo Omar Emiliano , Sánchez-Muñoz Fausto , Argüello-García Raúl , Sánchez-Lozada Laura Gabriela , Bojalil Rafael , Osorio-Alonso Horacio 
Published: September 2023

Background
Recent studies have suggested that metabolic syndrome (MS) encompasses a group of risk factors for developing chronic kidney disease (CKD). This work aimed to evaluate the antioxidant and anti-inflammatory effects of allicin in the kidney from an experimental model of MS.

Methods
Male Wistar rats (220–250 g) were used, and three experimental groups (n = 6) were formed: control (C), metabolic syndrome (MS), and MS treated with allicin (16 mg/Kg/day, gastric gavage) (MS+A). MS was considered when an increase of 20% in at least three parameters (body weight, systolic blood pressure (SBP), fasting blood glucose (FBG), or dyslipidemia) was observed compared to the C group. After the MS diagnosis, allicin was administered for 30 days.

Results
Before the treatment with allicin, the MS group showed more significant body weight gain, increased SBP, and FBG, glucose intolerance, and dyslipidemia. In addition, increased markers of kidney damage in urine and blood. Moreover, the MS increased oxidative stress and inflammation in the kidney compared to group C. The allicin treatment prevented further weight gain, reduced SBP, FBG, glucose intolerance, and dyslipidemia. Also, markers of kidney damage in urine and blood were decreased. Further, the oxidative stress and inflammation were decreased in the renal cortex of the MS+A compared to the MS group.

Conclusion
Allicin exerts its beneficial effects on the metabolic syndrome by considerably reducing systemic and renal inflammation as well as the oxidative stress. These effects were mediated through the Nrf2 pathway. The results suggest allicin may be a therapeutic alternative for treating kidney injury induced by the metabolic syndrome risk factors.
Genetical Variability among Ceratocystis fimbriata Isolates Causing Wilt Disease of Pomegranate
Authors: Raja  , Sunkad Gururaj , Amaresh Y. S.  
Published: September 2023

Pomegranate (Punica granatum L.) is an important fruit crop farmed all over the world, notably in the tropical and subtropical zones. It is afflicted by a number of diseases, the most serious of which is Ceratocystis fimbriata. Very little work is done on the genetical variability of C. fimbriata associated with pomegranate wilt in Karnataka and the morphological structures defining this species are reasonably defined, these characteristics are insufficient to recognize emergent grouping within C. fimbriata. The aim of this study is to confirm the identity of C. fimbriata isolates from pomegranate in Karnataka and to compare the DNA sequence of the internal transcribed spacer (ITS-1 and 4 regions) variability is the property of an organism to change its characters from one generation to the other. there is a need to study C. fimbriata based on molecular variability. Fifty isolates of C. fimbriata were amplified with a range of 600-650 bp length, twelve isolates were sequenced and deposited in the GenBank Maryland, USA database under the accession number KY038512- KY038523. All isolates from different districts of Karnataka show specific patterns of similarity according to geographical region.
Modulating the Photoresponsivity of Perovskite Photodetectors through Interfacial Engineering of Self‐Assembled Monolayers
Authors: Chang Ai‐Chun , Wu Ya‐Shuan , Chen Wei‐Cheng , Weng Yi‐Hsun , Lin Bi‐Hsuan , Chueh Chu‐Chen , Lin Yan‐Cheng , Chen Wen‐Chang 
Published: September 2023

AbstractPhotodetectors are one of the most essential optoelectronics nowadays. Perovskites have emerged as one of the potential materials for photodetectors due to their high absorption efficiency over a wide range of wavelengths, high charge mobility, strong mechanical deformability, and solution processability. In this study, interfacial engineering using self‐assembled monolayers (SAMs) is explored to improve the performance of perovskite photodetectors. SAMs with different terminal groups exhibit distinct surface energy, and they all result in a reduced exciton lifetime of the perovskite due to charge transfer between polycrystalline perovskite and the SAMs. In particular, the photodetector modified with (4‐hydroxyphenyl)phosphonic acid (OH) exhibits the highest electron mobility of 0.8 cm2 V−1 s−1 under 450‐nm light illumination. In addition, it shows excellent detector performance with an ultrafast photoresponse of < 14 ms, a high photoresponsivity of 5600 AW−1, and a high specific detectivity of 5.9 × 1010 Jones at a low light intensity of 18 µW cm−2. The excellent photoresponse and device switchability are attributed to the high surface energy of OH, the resulting homogeneous perovskite film morphology, the high charge transfer efficiency, and the favorable energy level alignment. The studies provide new prospects for the development of emerging perovskite photodetectors.
3D Centrifugation‐Enabled Priming of Synaptic Activation Promotes Primary T Cell Expansion
Authors: Jiang Ruoyu , Chen Yu‐Hsi , Parajuli Ritesh , Agrawal Anshu , Lee Abraham P. 
Published: September 2023

AbstractAutologous cell therapy depends on T lymphocyte expansion efficiency and is hindered by suboptimal interactions between T cell receptors (TCR) and peptide‐MHC molecules. Various artificial antigen presenting cell systems that enhance these interactions are often labor‐intensive, fabrication costly, highly variable, and potentially unscalable toward clinical setting. Here, 3D centrifugation‐enabled priming of T cell immune‐synapse junctions is performed to generate tight T cell–Dynabead aggregates at a rate 200‐fold faster than that of conventional 24‐h bulk shaking. Furthermore, by forming T cell–Dynabead aggregates in the starting culture, two‐ to sixfold greater T cell expansion is achieved over conventional T cell expansion for cancer patient‐derived primary T cells while limiting over‐activation. Creating 3D T cell–Dynabead aggregates as the “booster” material enables highly efficient polyclonal T cell expansion without the need for complex surface modification of artificial antigen‐presenting cells (APCs). This method can be modularly adapted to existing T cell expansion processes for various applications, including adoptive cell therapies (ACTs).
Memcapacitor Crossbar Array with Charge Trap NAND Flash Structure for Neuromorphic Computing
Authors: Hwang Sungmin , Yu Junsu , Song Min Suk , Hwang Hwiho , Kim Hyungjin 
Published: September 2023

AbstractThe progress of artificial intelligence and the development of large‐scale neural networks have significantly increased computational costs and energy consumption. To address these challenges, researchers are exploring low‐power neural network implementation approaches and neuromorphic computing systems are being highlighted as potential candidates. Specifically, the development of high‐density and reliable synaptic devices, which are the key elements of neuromorphic systems, is of particular interest. In this study, an 8 × 16 memcapacitor crossbar array that combines the technological maturity of flash cells with the advantages of NAND flash array structure is presented. The analog properties of the array with high reliability are experimentally demonstrated, and vector‐matrix multiplication with extremely low error is successfully performed. Additionally, with the capability of weight fine‐tuning characteristics, a spiking neural network for CIFAR‐10 classification via off‐chip learning at the wafer level is implemented. These experimental results demonstrate a high level of accuracy of 92.11%, with less than a 1.13% difference compared to software‐based neural networks (93.24%).
Tuned Reactivity at the Lithium Metal–Argyrodite Solid State Electrolyte Interphase
Authors: Hao Hongchang , Liu Yijie , Greene Samuel M. , Yang Guang , Naik Kaustubh G. , Vishnugopi Bairav S. , Wang Yixian , Celio Hugo , Dolocan Andrei , Tsai Wan‐Yu , Fang Ruyi , Watt John , Mukherjee Partha P. , Siegel Donald J. , Mitlin David 
Published: September 2023

AbstractThin intermetallic Li2Te–LiTe3 bilayer (0.75 µm) derived from 2D tellurene stabilizes the solid electrolyte interphase (SEI) of lithium metal and argyrodite (LPSCl, Li6PS5Cl) solid‐state electrolyte (SSE). Tellurene is loaded onto a standard battery separator and reacted with lithium through single‐pass mechanical rolling, or transferred directly to SSE surface by pressing. State‐of‐the‐art electrochemical performance is achieved, e.g., symmetric cell stable for 300 cycles (1800 h) at 1 mA cm−2 and 3 mAh cm−2 (25% DOD, 60 µm foil). Cryo‐stage focused ion beam (Cryo‐FIB) sectioning and Raman mapping demonstrate that the Li2Te–LiTe3 bilayer impedes SSE decomposition. The unmodified Li–LPSCl interphase is electrochemically unstable with a geometrically heterogeneous reduction decomposition reaction front that extends deep into the SSE. Decomposition drives voiding in Li metal due to its high flux to the reaction front, as well as voiding in the SSE due to the associated volume changes. Analysis of cycled SSE found no evidence for pristine (unreacted) lithium metal filaments/dendrites, implying failure driven by decomposition phases with sufficient electrical conductivity that span electrolyte thickness. DFT calculations clarify thermodynamic stability, interfacial adhesion, and electronic transport properties of interphases, while mesoscale modeling examines interrelations between reaction front heterogeneity (SEI heterogeneity), current distribution, and localized chemo‐mechanical stresses.
Timing and level of educational attainment and late‐life cognition in the KHANDLE study
Authors: Soh Yenee , Whitmer Rachel A. , Mayeda Elizabeth Rose , Glymour M. Maria , Eng Chloe W. , Peterson Rachel L. , George Kristen M. , Chen Ruijia , Quesenberry Charles P. , Mungas Dan M. , DeCarli Charles S. , Gilsanz Paola 
Published: September 2023

AbstractINTRODUCTIONThe timing of educational attainment may modify its effects on late‐life cognition, yet most studies evaluate education only at a single time point.METHODSKaiser Healthy Aging and Diverse Life Experiences (KHANDLE) Study cohort participants (N = 554) reported educational attainment (dichotomized at any college education) at two time points, and we classified them as having low, high, or later‐life high educational attainment. Linear mixed‐effects models estimated associations between educational attainment change groups and domain‐specific cognitive outcomes (z‐standardized).RESULTSCompared to low educational attainment, high (β= 0.59 SD units; 95% confidence interval [CI]: 0.39, 0.79) and later‐life high educational attainment (β = 0.22; 95% CI: 0.00, 0.44) were associated with higher executive function. Only high educational attainment was associated with higher verbal episodic memory (β = 0.27; 95% CI: 0.06, 0.48).DISCUSSIONLevel and timing of educational attainment are both associated with domain‐specific cognition. A single assessment for educational attainment may inadequately characterize protective associations with late‐life cognition.Highlights
Few studies have examined both level and timing of educational attainment on cognition.
Marginalized populations are more likely to attain higher education in adulthood.
Higher educational attainment in late life is also associated with higher cognition.
Visible‐light‐switchable Chalcone‐Flavylium Photochromic Systems in Aqueous Media
Authors: Maity Manik Lal , Mahato Samyadeb , Bandyopadhyay Subhajit 
Published: September 2023

AbstractThe chalcone‐flavylium photochromic system switches in aqueous media. However, the chalcone→flavylium conversion requires detrimental ultra‐violet (UV) light for the switching which deters their applications in the biological domain. To address this issue, we have synthesized strategically modified chalcone scaffolds that can be reversibly switched to the flavylium forms with visible light ranging from 456 nm (blue) to 640 nm (red).
Promoted Photocatalytic Hydrogen Evolution by Tuning the Electronic State of Copper Sites in Metal‐Organic Supramolecular Assemblies
Authors: Liu Ning , Jiang Jialong , Chen Zhonghang , Wu Boyuan , Zhang Shiqi , Zhang Yi‐Quan , Cheng Peng , Shi Wei 
Published: September 2023

AbstractThe electronic state in terms of charge and spin of metal sites is fundamental to govern the catalytic activity of a photocatalyst. Herein, we show that modulation of the electronic states of Cu sites, without changing the coordination environments, of two metal‐organic supramolecular assemblies based on π⋅⋅⋅π stacking can significantly improve photocatalytic activity. The use of these heterogeneous photocatalysts, without using noble metal cocatalysts, resulted in an increase of the hydrogen production rate from 522 to 3620 μmol h−1 g−1. A systematical analysis revealed that the charge density and spin density of the metal centers are efficiently modulated via the modulation of the coordination fields around active copper (II) centers by the variation of the non‐coordination groups of terminal ligands, leading to the significant enhancement of photocatalytic activity. This work provides an insight into the electronic state of active metal centers for designing high‐performance photocatalysts.
Enantioconvergent Palladium‐Catalyzed Alkylation of Tertiary Allylic C−H Bonds
Authors: Nong Zhong‐Sheng , Chen Xin‐Ran , Wang Pu‐Sheng , Hong Xin , Gong Liu‐Zhu 
Published: September 2023

AbstractEnantioconvergent catalysis enables the conversion of racemic molecules into a single enantiomer in perfect yield and is considered an ideal approach for asymmetric synthesis. Despite remarkable advances in this field, enantioconvergent transformations of inert tertiary C−H bonds remain largely unexplored due to the high bond dissociation energy and the surrounding steric repulsion that pose unparalleled constraints on bond cleavage and formation. Here, we report an enantioconvergent Pd‐catalyzed alkylation of racemic tertiary allylic C−H bonds of α‐alkenes, providing a unique approach to access a broad range of enantioenriched γ,δ‐unsaturated carbonyl compounds featuring quaternary carbon stereocenters. Mechanistic studies reveal that a stereoablative event occurs through the rate‐limiting cleavage of tertiary allylic C−H bonds to generate σ‐allyl‐Pd species, and the achieved E/Z‐selectivity of σ‐allyl‐Pd species effectively regulates the diastereoselectivity via a nucleophile coordination‐enabled SN2′‐allylation pathway.
Hyperbranched Polyborosiloxanes: Non‐traditional Luminescent Polymers with Red Delayed Fluorescence
Authors: He Yanyun , Feng Weixu , Qiao Yujie , Tian Zhixuan , Tang Ben Zhong , Yan Hongxia 
Published: September 2023

AbstractNon‐traditional fluorescent polymers have attracted significant attention for their excellent biocompatibility and diverse applications. However, designing and preparing non‐traditional fluorescent polymers that simultaneously possess long emission wavelengths and long fluorescence lifetime remains challenging. In this study, a series of novel hyperbranched polyborosiloxanes (P1–P4) were synthesized. As the electron density increases on the monomer diol, the optimal emission wavelengths of the P1–P4 polymers gradually red‐shift to 510, 570, 575, and 640 nm, respectively. In particular, P4 not only exhibits red emission but also demonstrates delayed fluorescence with a lifetime of 9.73 μs and the lowest critical cluster concentration (1.76 mg/mL). The experimental results and theoretical calculations revealed that the synergistic effect of dual heteroatom‐induced electron delocalization and through‐space O⋅⋅⋅O and O⋅⋅⋅N interaction was the key factor contributing to the red‐light emission with delayed fluorescence. Additionally, these polymers showed excellent potential in dual‐information encryption. This study provides a universal design strategy for the development of unconventional fluorescent polymers with both delayed fluorescence and long‐wavelength emission.
The Development of Aldehyde Catalytic System
Authors: Chen Jinli , Yang Xiaoqun , Huang Yixian , Zheng Zhiguo , Li Tingting 
Published: September 2023

AbstractAldehyde catalysts have proven to be highly effective in facilitating and accelerating a wide range of challenging transformations in organic chemistry. This article is structured into three main sections, focusing on the utilization of aldehydes as organocatalysts, the aldehydes/transition metals catalytic systems, and photochemical initiators. Finally, we provide a concise summary of the advancements in this fascinating research field, offering our perspectives and insights.
Spearman‐like correlation measure adjusting for covariates in bivariate survival data
Authors: Eden Svetlana K. , Li Chun , Shepherd Bryan E. 
Published: September 2023

AbstractWe propose an extension of Spearman's correlation for censored continuous and discrete data that permits covariate adjustment. Previously proposed nonparametric and semiparametric Spearman's correlation estimators require either nonparametric estimation of the bivariate survival surface or parametric assumptions about the dependence structure. In practice, nonparametric estimation of the bivariate survival surface is difficult, and parametric assumptions about the correlation structure may not be satisfied. Therefore, we propose a method that requires neither and uses only the marginal survival distributions. Our method estimates the correlation of probability‐scale residuals, which has been shown to equal Spearman's correlation when there is no censoring. Because this method relies only on marginal distributions, it tends to be less variable than the previously suggested nonparametric estimators, and the confidence intervals are easily constructed. Although under censoring, it is biased for Spearman's correlation as our simulations show, it performs well under moderate censoring, with a smaller mean squared error than nonparametric approaches. We also extend it to partial (adjusted), conditional, and partial‐conditional correlation, which makes it particularly relevant for practical applications. We apply our method to estimate the correlation between time to viral failure and time to regimen change in a multisite cohort of persons living with HIV in Latin America.
Proportion and number of incident cancer deaths in coronary artery disease
Authors: Liu Jin , Chen Shiqun , Zhou Yang , Huang Haozhang , Li Qiang , Liang Yan , Dong Shaohong , Huang Xiaoyu , Chen Liling , Zheng Xueyan , Meng Ruilin , Jia Congzhuo , Chen Jiyan , Tan Ning , Liu Yong 
Published: September 2023

AbstractBackgroundGlobally, coronary artery disease (CAD) and cancer are the leading causes of death. Studies focusing on the proportion and spectrum of cancer mortality among CAD patients are lacking. We aim to characterize the proportion and spectrum of cancer‐specific mortality among patients with CAD.MethodsWe analyzed 93,797 hospitalized survivors with angiographically documented CAD between 2007 and 2020 (mean age: 62.8 ± 11.1 years, 24.7% female) from Cardiorenal ImprovemeNt II (CIN‐II) cohort.ResultsDuring the median follow‐up of 4.8 years (IQR: 2.6–7.5), 13,162 (14.0%) patients died after discharge. A total of 1223/7703 (15.8% of cause‐specific death) CAD patients died of cancer. The three most common types of cancer‐specific death were lung (36.1%), liver (13.3%), and colorectum cancer (12.8%). Furthermore, male (adjusted HR 2.38, 95% CI: 1.99–2.85) and older (≥60 vs. <60 years, adjusted HR 3.25, 95%CI 2.72–3.88) patients had a significantly increased cancer‐specific mortality.ConclusionsOur data suggest that nearly one‐sixth of death is accounted for cancer among CAD patients within a median follow‐up of 4.8 years. Lung, liver, and colorectum cancer are top three cancer‐specific mortality. Further studies are needed to reduce cancer mortality for CAD patients, especially in older and male ones.Trail Registration(ClinicalTrials.gov NCT05050877).
Sirtuins and autophagy in lipid metabolism
Authors: Sun Xuan , Yang Xiaoting , Gui Wanfei , Liu Songling , Gui Qingjun 
Published: September 2023

AbstractSirtuins are a family of NAD+‐dependent deacetylases that regulate some important biological processes, including lipid metabolism and autophagy, through their deacetylase function. Autophagy is a new discovery in the field of lipid metabolism, which may provide a new idea for the regulation of lipid metabolism. There are many tandem parts in the regulation process of lipid metabolism and autophagy of sirtuins protein family. This paper summarized these tandem parts and proposed the possibility of sirtuins regulating lipid autophagy, as well as the interaction and synergy between sirtuins protein family. Currently, some natural drugs have been reported to affect metabolism by regulating sirtuins, some of which regulate autophagy by targeting sirtuins.
Evaluating insecticide application timings against billbugs (Sphenophorus spp.) using a degree‐day model and calendar‐based approach in the Intermountain West
Authors: Van Dyke Adam , Wickwar Desireè , Dupuy Madeleine M. , Ramirez Ricardo A. 
Published: September 2023

AbstractRecommendations for timing insecticides against billbugs have historically been based on adult activity and a corresponding degree‐day (DD) model that is optimized for the eastern United States. A DD model was recently developed for billbugs in Utah and Idaho that refines predictions of adult activity based on the phenology of species that inhabit the Intermountain West (IMW) region. However, timings still follow eastern US recommendations and have not been verified with field applications in the IMW. We evaluated the synthetic insecticides Merit 75 WP and Acelepryn 1.67 SC and the bioinsecticides Grandevo and Venerate for controlling larvae when using the eastern recommended treatment thresholds of 30% and 50% adult activity (adults collected in pitfall traps) based on the Utah–Idaho model for two years. Applications of insecticides at these adult emergence thresholds provided >75% control of billbug larvae preventively and curatively in Utah, confirming these are appropriate action thresholds to use in the Utah–Idaho model to time insecticides. Insecticides applied at various calendar dates around these recommended timings, but typical for a professional applicator in Utah based on site history and weather, were assigned model‐calculated DD for testing in the Utah–Idaho model. Instances where a professional applicator treated within model‐predicted timings resulted in larval reductions, further validating that the model parameters are good recommendations for the region and should be adopted. Additionally, several calendar‐based applications made earlier or later than optimal timings based on model predictions were effective, suggesting that applicators have flexibility for timing applications when targeting larvae.