bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real‐world analysis of patients with haemophilia A and haemophilia A carriers in the United States: Demographics, clinical characteristics and costs
Authors: Batt Katharine , Xing Shan , Kuharic Maja , Bullano Michael , Caicedo Jorge , Chakladar Sreya , Markan Riddhi , Farahbakhshian Sepehr 
Published: May 2023

AbstractIntroductionFemales with haemophilia A (HA [FHAs]) and HA carriers (HACs) have an increased risk of bleeding and complications compared to the general population.AimTo examine the characteristics, billed annualised bleed rates (ABRb), costs and healthcare resource utilisation for males with HA (MHAs), FHAs and HACs in the United States.MethodsData were extracted from the IBM® MarketScan® Research Databases (Commercial and Medicaid) for claims during the index period (July 2016 to September 2018) and analysed across MHAs, FHAs and HACs.ResultsDual diagnosis females (DDFs; both HA and HAC claims) were grouped as a separate cohort. MHAs were generally younger than females (all cohorts) by up to 19 years (Commercial) and 23 years (Medicaid). ABRb >0 was more frequent in females. Factor VIII claims were higher for MHAs versus female cohorts. Joint‐related health issues were reported for 24.4 and 25.6% (Commercial) and 29.3 and 26.6% (Medicaid) of MHAs and FHAs, respectively; lower rates were reported in the other two cohorts. Heavy menstrual bleeding claims occurred for approximately a fifth (Commercial) to a quarter (Medicaid) of female cohorts. All‐cause emergency department and inpatient visits in FHAs and DDFs were similar to, or more frequent than, those in MHAs; bleed‐related inpatient visits were infrequent. In MHAs (Commercial), mean all‐cause total costs ($214,083) were higher than in FHAs ($40,388), HACs ($15,647) and DDFs ($28,320) with similar trends for Medicaid patients.ConclusionsFHAs and HACs may be undermanaged and undertreated. Further research is needed to fully understand these cohorts' bleeding rates, long‐term complications and costs.
The post‐annealing effect on tribological and corrosion behaviors of CrN/AlCrN multilayered coating applied by CAE‐PVD
Authors: Lotfi‐Khojasteh Erfan , Elmkhah Hassan , Nouri Meisam , Imantalab Omid , Fattah‐Alhosseini Arash 
Published: May 2023

AbstractThe present study investigated the wear and electrochemical behaviors of CrN/AlCrN multilayered coatings post‐annealed at 300, 450, and 600°C temperatures. The cathodic arc evaporation technique has been utilized to deposit the coatings. Scanning electron microscope, field emission SEM, energy‐dispersive X‐ray, grazing incidence X‐ray diffraction, and Rockwell‐C indenter methods were used to characterize the coatings and to investigate the interdiffusion between the multilayered CrN/AlCrN and the H13 base metal. The results showed that the sharp interface of the CrN and AlCrN layers was blurred by the annealing process supporting the interdiffusion of the layers. The reciprocating wear test and the microhardness tester were used to evaluate the coatings’ mechanical behavior. The hardness and roughness of the coatings were increased by increasing the post‐annealing temperature. The smallest wear rates were observed for the samples treated at 300 and 450°C, which were approximately 17 times and 12 times smaller than the wear rate of the sample annealed at 600°C. Electrochemical testing was used to study the corrosion behavior of the coatings. The results showed that by increasing annealing temperature, corrosion resistances of the coatings are improved. As a result, the corrosion current density of the 600°C annealed coating was approximately 434 times smaller than as‐deposited coatings.
Early finishers: How EFL students bring tasks to early completion and what happens next
Authors: Stone Paul 
Published: May 2023

AbstractIn classrooms that use small‐group tasks, some groups may finish earlier than others and there may be concern that early finishers will become disengaged. However, early finishing remains relatively under‐examined. This paper uses conversation analysis to investigate how EFL students in a Japanese university finish tasks early. It describes a set of practices students use to finish tasks and reveals how students orient to the achievement of task outcomes. The study finds that students may have more to say on task topics than a task allows, and early finishers may develop these topics in post‐task talk in the target language. The paper argues that early finishing may lead to useful language practice and teachers should therefore be cautious when assigning extra work to early finishers.
Female patient violence experienced by female qualified nurses working in an inpatient psychiatric department
Authors: Alanazi Badriah , McAndrew Sue , Warne Tony 
Published: May 2023

AbstractWhilst there is an increasing prevalence of healthcare staff facing aggression, psychiatric nurses are thought to be most at risk; with such events being a hazard to their physical, emotional and psychological health. This study explored how patient violence is experienced by qualified nurses employed in an in‐patient psychiatric facility in the Kingdom of Saudi Arabia (KSA). As male and female patients and nurses are segregated in Saudi healthcare settings, this study focused on female patient violence against female psychiatric nurses. Both the immediate and more long‐term impacts were explored, together with approaches that could potentially facilitate avoiding, reducing and managing aggression within the work setting. The study adopted a qualitative descriptive design and used purposive sampling to recruit nine psychiatric nurses working in an in‐patient setting, from a single KSA medical facility. Inclusion criteria required participants to be licensed, registered nurses, who, during the last 10 years, had worked in an acute in‐patient psychiatric ward for adult females, and to have experienced some form of patient aggression. Semi‐structured, one‐to‐one interviews were used to gather data, which was then subjected to thematic analysis. Two dominant themes were identified: (i) occurrence of violence and (ii) determination of violence. It was concluded that female psychiatric nurses were adversely affected by aggression towards them from female patients. Although the nurses considered this behaviour to be part of their nursing role, they reported minimal support from institutional managers, peers and their relatives.
A critical re‐evaluation of Mohs micrographic surgery for a facial basal cell carcinoma in older adults: Should we waive this treatment in certain patients?
Authors: Van Coile Laura , Brochez Lieve , Verhaeghe Evelien , Boone Barbara , Meertens Annick , Ongenae Katia , Hoorens Isabelle 
Published: May 2023

AbstractBackgroundSkin cancer incidences are increasing. Treatment for basal cell carcinomas (BCCs) can be questioned in certain patients. Treatment options are various, but Mohs micrographic surgery (MMS) has the highest cure rate. It is, however, time‐consuming and results in high logistical burden and treatment costs for both patients and society.ObjectivesThis study critically re‐evaluates MMS for facial BCCs in older adults. The main objective is to examine all clinical, tumour and patient characteristics in relation to safety and survival to detect a subgroup in which MMS was not the best choice. The overall aim is to identify characteristics that support clinical decision‐making in daily practice.MethodsPatients that received MMS between November 1998 and December 2012 were included. Only patients >75 years with a facial BCC were withheld for analysis. This is a retrospective cohort study, since evaluating the outcome of MMS in accordance with life expectancy is the main objective. Patient charts were evaluated towards comorbidities, complications and survival.ResultsThis cohort comprises 207 patients. Median survival was 7.85 years. The age‐adjusted Charlson comorbidity index (aCCI) was divided into low/medium scores (aCCI < 6) and high scores (aCCI ≥ 6). Median survival was 11.58 years in the low aCCI group and 3.60 years in the high aCCI group (p < 0.001). There was a very strong association between high aCCI and survival (HR, 6.25; 95% CI, 3.83–10.21). Other characteristics were not associated with survival.ConclusionsClinicians should assess the aCCI in older patients presenting with a facial BCC before deciding if MMS is an eligible treatment option. High aCCI has shown to be an indicator for low median survival, even in MMS patients with usually high functional status. MMS should be waived as treatment in older patients with high aCCI scores in favour of other, less intensive and less expensive treatment options.
Life history of the endemic Hawaiian hogfish Bodianus albotaeniatus: age, growth and reproduction
Authors: Wiley John , Pardee Cassandra 
Published: May 2023

AbstractGrowth rate, longevity, maturity and spawning seasonality were estimated for the endemic Hawaiian hogfish Bodianus albotaeniatus. The sex‐specific von Bertalanffy growth parameters are L∞ = 339 mm fork length (LF) and K = 0.66 year−1 for females and L∞ = 417 mm LF and K = 0.33 year−1 for males. The maximum age is 22 years. Histological gonad analysis and the absence of small and young males indicate a monandric protogynous hermaphrodite. Size and age at maturity for combined sexes are L50 = 238 mm LF and A50 = 1.6 years.
Evaluation of antimicrobial activity and mechanism of Mentha longifolia L. essential oil
Authors: Li Shengjie , Cheng Feng , Cao Xueqin , Mahinur Bakri , Maiwulanjiang Maitinuer 
Published: May 2023

AbstractAs the interest in “natural” and “safe” products grows, the use of natural products instead of synthetic preservatives to combat food spoilage and poisoning caused by microorganisms during processing and storage has become a prioritized option. The present research evaluated the antibacterial activity of the Mentha longifolia L. essential oil (MLEO) against several pathogenic bacteria, and the mechanism of action against methicillin‐resistant Staphylococcus aureus (MRSA). Gas Chromatography Quadrupole Time‐of‐Flight Mass Spectrometry (GC‐Q‐TOF MS) analysis suggested that main components of MLEO were carvone (47.39%) and limonene (12.48%). The oil showed considerable antibacterial activity with MIC values of 0.394–1.576 mg/mL, and could be a promising bactericide. Non‐targeted metabolomics analysis based on GC‐Q‐TOF MS identified 66 different metabolites, and Kyoto Encyclopedia of Genes and Genomes enrichment analysis of these metabolites revealed that MLEO achieves the effects by affecting amino acid metabolism in MRSA.
It's not the rotten apples!Why family scholars should adopt a structural perspective on racism
Authors: Bonilla‐Silva Eduardo 
Published: May 2023

AbstractIn this article, I urge family scholars to anchor their race work on the structural racism perspective. First, I provide some limitations of the prejudice problematic used by most family scholars. Second, I discuss the basic components of my structural theory, which I call the racialized social system approach. Third, I bolster my original theorization with a new conceptual map to make the structure intelligible—to account for why actors, for the most part, behave in ways that reproduce the racial order. In this discussion, I highlight the importance of the “white habitus” in shaping the lives and behaviors of White people. Lastly, I conclude by summarizing my claims and asking family scholars to continue deepening their work on structural racism and families, as well as on fighting how it shapes their own fields and lives.
Ustekinumab is a promising option for the treatment of postoperative recurrence of Crohn's disease
Authors: Macaluso Fabio Salvatore , Grova Mauro , Mocciaro Filippo , Di Mitri Roberto , Privitera Antonino Carlo , Distefano Maria Emanuela , Vitello Alessandro , Camilleri Salvatore , Ferracane Concetta , Pluchino Dario , Belluardo Nunzio , Giangreco Emiliano , Fries Walter , Viola Anna , Cappello Maria , D'Amato Livia , Bertolami Carmelo , Ventimiglia Marco , Renna Sara , Casà Angelo , D'Antonio Elvira , De Vivo Simona , Orlando Ambrogio ,   Sicilian Network for Inflammatory Bowel Disease (SN‐IBD)
Published: May 2023

AbstractBackground and AimPostoperative recurrence (POR) following ileocolonic resection is a major concern in patients with Crohn's disease (CD). The role of ustekinumab (UST) in this setting is poorly known.MethodsAll consecutive CD patients with a baseline colonoscopy at 6–12 months from ileocolonic resection showing POR (Rutgeerts score ≥ i2) who were treated with UST after the baseline colonoscopy and with an available post‐treatment endoscopy, were extracted from the cohort of the Sicilian Network for Inflammatory Bowel Diseases (SN‐IBD). The primary outcome was endoscopic success, defined as reduction of at least one point of Rutgeerts score. The secondary outcome was clinical success, assessed at the end of follow‐up. Reasons for clinical failure included mild clinical relapse (Harvey–Bradshaw index 5–7), clinically relevant relapse (Harvey–Bradshaw index > 7), and need for new resection.ResultsForty‐four patients were included (mean follow‐up: 17.8 ± 8.4 months). The baseline postoperative colonoscopy showed severe POR (Rutgeerts score i3 or i4) in 75.0% of patients. The post‐treatment colonoscopy was performed after a mean of 14.5 ± 5.5 months following initiation of UST. Endoscopic success was reported in 22 out of 44 (50.0%) patients, of whom 12 (27.3%) achieved a Rutgeerts score i0 or i1. Clinical success at the end of follow‐up was reported in 32 out of 44 patients (72.7%); none of the 12 patients with clinical failure had achieved endoscopic success at post‐treatment colonoscopy.ConclusionsUstekinumab could be a promising option for the treatment of POR of CD.
Optimal Sequential Selling Mechanism and Deal Protections in Mergers and Acquisitions
Authors: CHEN YI , WANG ZHE 
Published: May 2023

ABSTRACTWe study the dynamic profit‐maximizing selling mechanism in a merger and acquisitions (M&A) environment with costly bidder entry and without entry fees. Depending on the parameters, the optimal mechanism is implemented by a standard auction or by a two‐stage procedure with exclusive offers to one bidder followed by an auction potentially favoring that bidder. The optimal mechanism may involve common deal protections like termination fees, asset lockups, or stock option lockups. Our proposed procedures resemble sales of targets filing Chapter 11 bankruptcy or M&A involving public targets, and they shed light on how to use deal protections in practice.
The Problem of Inclusion: Feminist Critique in Religious Ethics
Authors: Bialek Fannie 
Published: May 2023

ABSTRACTReligious ethics was founded on a commitment to inclusion, welcoming projects from and about different religious and philosophical traditions. This paper argues that the increasing welcome of feminist ethics in the JRE also reveals a tension in the field between inclusion and critique: where feminist ethics is included as another tradition of ethical inquiry, its critical claims can be escaped by appeal to difference from the traditions it seeks to engage. The response to feminist critique should not be to applaud its inclusion without responding to its claims. Where this occurs, religious ethicists must renegotiate the terms of inclusion and the borders of difference. Feminist critique thus requires a return to founding questions of this journal, and the field, about the terms on which different traditions can be discussed and engaged in a common, critical conversation of religious ethics.
Genetic variation and identification of Meloidogyne graminis populations from golf fields in Antalya province of Türkiye
Authors: Uysal Gülsüm , Mıstanoğlu Ibrahim , Devran Zübeyir 
Published: May 2023

AbstractRoot‐knot nematodes (RKNs), belonging to genus Meloidogyne, cause economically damage on turfgrasses areas worldwide. Many RKN species have been identified in studies conducted in golf courses around the world. However, no study has been carried out on RKNs in golf fields so far in Türkiye. In this study, root and soil samples were taken from different golf courses in Antalya which has the biggest golf areas of Türkiye. Meloidogyne graminis (Sledge & Golden, 1964) Whitehead, 1968 was identified in six of forty‐five samples by using species‐specific primers. In addition, SRAP primers were used to investigate polymorphism among M. graminis populations and other RKN species. The number of average polymorphic fragments per primer was 10.18. The mean polymorphism information content and coph.corr (r) value is .88 and .88, respectively. Phylogenetic analysis showed that M. graminis populations grouped different distant to other trophic and temperate RKNs. This is the first report on presence of M. graminis in Türkiye.
Trust in God: The COVID‐19 Pandemic's Impact on Religiosity in China
Authors: Ruan Rongping , Vaughan Kenneth R. , Han Dan 
Published: May 2023

AbstractEmerging research shows the COVID‐19 pandemic has made substantial changes to the religious climate of several nations. Surprisingly, China, the outbreak center of the pandemic, has been scarcely researched. Our study investigates how the COVID‐19 pandemic has evoked new religious disaster responses and provided psychological coping mechanisms during the pandemic. We also explore how the pandemic explains surprising rates of religiosity in China. Scholars have long proposed that religious resurgence in China has been a result of individuals seeking stability in turbulent times. We bridge parallel Literatures in these areas and treat the pandemic as a natural experiment for evaluating religious behavior over time as conditioned by heightened risk perception. Utilizing a difference‐in‐differences estimation strategy with panel data, our study reveals that the pandemic has led to a significant increase in religiosity in China, particularly in religious areas most affected by the pandemic. We propose that even in a highly regulative religious environment, with most of its population being religiously unaffiliated, religion is a significant resource for coping in China. We take an innovative approach to demonstrate this by utilizing online search data. Our research speaks to the sociology of religion, the social psychology of risk perception, and makes application to emerging research on the unfolding COVID‐19 pandemic.
Safety and effectiveness of the sodium‐glucose cotransporter inhibitor bexagliflozin in cats newly diagnosed with diabetes mellitus
Authors: Hadd Michael J. , Bienhoff Stephen E. , Little Susan E. , Geller Samuel , Ogne‐Stevenson Jennifer , Dupree Thomas J. , Scott‐Moncrieff J. Catharine 
Published: May 2023

AbstractBackgroundBexagliflozin is a sodium‐glucose cotransporter 2 (SGLT2) inhibitor. A pilot study has shown that bexagliflozin can decrease dependence on exogenous insulin in cats with diabetes mellitus (DM).ObjectiveTo evaluate the safety and effectiveness of bexagliflozin as a monotherapy for DM in previously untreated cats.AnimalsEighty‐four client‐owned cats.MethodsHistorically controlled prospective open‐label clinical trial. Cats were dosed PO with 15 mg bexagliflozin once daily for 56 days, with a 124‐day extension to evaluate safety and treatment effect durability. The primary endpoint was the proportion of cats experiencing a decrease in hyperglycemia and improvement in clinical signs of hyperglycemia from baseline on day 56.ResultsOf 84 enrolled cats, 81 were evaluable on day 56, and 68 (84.0%) were treatment successes. Decreases in mean serum glucose, fructosamine, and β‐hydroxybutyrate (β‐OHB) concentrations were observed, and investigator assessments of cat neurological status, musculature, and hair coat quality improved. Owner evaluations of both cat and owner quality of life were favorable. The fructosamine half‐life in diabetic cats was found to be 6.8 days. Commonly observed adverse events included emesis, diarrhea, anorexia, lethargy, and dehydration. Eight cats experienced serious adverse events, 3 of which led to death or euthanasia. The most important adverse event was euglycemic diabetic ketoacidosis, diagnosed in 3 cats and presumed present in a fourth.Conclusion and Clinical ImportanceBexagliflozin decreased hyperglycemia and observed clinical signs in cats newly diagnosed with DM. As a once‐daily PO medication, bexagliflozin may simplify management of DM in cats.
Medical causes of poor performance and their associations with fitness in Standardbred racehorses
Authors: Lo Feudo Chiara M. , Stucchi Luca , Conturba Bianca , Stancari Giovanni , Zucca Enrica , Ferrucci Francesco 
Published: May 2023

AbstractBackgroundPoor performance is a multifactorial syndrome of racehorses, commonly associated with subclinical disorders, which can be diagnosed by exercise testing.ObjectivesDescribe the prevalence of medical causes of poor performance in Standardbreds unassociated with lameness, and evaluate their relationships with fitness variables measured by exercise treadmill test.AnimalsHospital population of 259 nonlame Standardbred trotters referred for poor performance.MethodsThe horses' medical records were retrospectively reviewed. Horses underwent a diagnostic protocol including resting examination, plasma lactate concentration, treadmill test with continuous ECG and assessment of fitness variables, creatine kinase activity, treadmill endoscopy, postexercise tracheobronchoscopy, bronchoalveolar lavage (BAL), and gastroscopy. The prevalence of different disorders was evaluated, including cardiac arrhythmias, exertional myopathies, dynamic upper airway obstructions (DUAOs), exercise‐induced pulmonary hemorrhage (EIPH), moderate equine asthma (MEA), and gastric ulcers (EGUS). The associations of these disorders with fitness variables were investigated individually and using multivariable models.ResultsModerate equine asthma and EGUS were the most common disorders, followed by EIPH, DUAOs, cardiac arrhythmias, and exertional myopathies. Hemosiderin score was positively correlated with BAL neutrophils, eosinophils, and mast cells; increased creatine kinase activity was associated with BAL neutrophilia, DUAOs, premature complexes, and squamous gastric disease. Treadmill velocity at a plasma lactate concentration of 4 mmol/L and at heart rate of 200 beats per minute was negatively affected by BAL neutrophilia, multiple DUAOs, exertional myopathies, and squamous gastric disease.ConclusionsThe multifactorial nature of poor performance was confirmed, with MEA, DUAOs, myopathies and EGUS representing the main diseases involved in fitness impairment.
Introduction to symposium on Philosophy and the art of writing by Richard Shusterman
Authors: Kramer Eli 
Published: May 2023

AbstractThis introductory piece provides context for this symposium on Richard Shusterman's new book, Philosophy and the Art of Writing. The piece reflects on the symposium genre from Plato's classic dialogue to its form today. It claims that Shusterman's work asks us to take this kind of philosophical writing more seriously, and for that reason the symposium itself has taken on a different structure. The piece discusses how each of the contributors responding to the book (with Shusterman leading the way), Eli Kramer, Randall Auxier, and Charles Johnson, have engaged in practicing, nurturing, and supporting broad modes of philosophical writing, and in turn why they have chosen to do so in this context.