bluuebunny/crossref_metadata_2025_split huggingface dataset:
The compositional diversity and temporal evolution of an active andesitic arc stratovolcano: Tongariro, Taupō Volcanic Zone, New Zealand
Authors: Pure Leo R. , Wilson Colin J. N. , Charlier Bruce L. A. , Gamble John A. , Townsend Dougal B. , Leonard Graham S. 
Published: April 2023

AbstractNew geochemical data, including Sr–Nd–Pb isotopes for whole-rock and groundmass samples, are reported for edifice-forming eruptives at Tongariro volcano, New Zealand, which span its ~ 350 ka to late Holocene history. Tongariro eruptives are medium-K basaltic-andesites to dacites (53.0–66.2 wt% SiO2) that evolved via assimilation-fractional crystallisation (AFC) processes partly or mostly in the uppermost 15 km of the crust. When ordered chronologically using a high-resolution 40Ar/39Ar-dated eruptive stratigraphy, the compositional data show systematic 10–130 kyr cycles. Mafic replenishment events inferred from MgO values occurred at ~ 230, ~ 151, ~ 88 and ~ 56 ka and in the late Holocene, with high-MgO flank vents erupting at ~ 160, ~ 117, ~ 35 and ~ 17.5 ka. Cycles in Sm/Nd, 87Sr/86Sr, 143Nd/144Nd and Pb isotopic ratios, which are decoupled from MgO, K2O and Rb/Sr cycles, indicate periods of prolonged crustal residence of magmas from ~ 230 to ~ 100 ka and ~ 95 to ~ 30 ka. AFC modelling shows that intermediate and silicic melt compositions, with r-values between 0.1 and 1, are needed to reproduce Tongariro compositional arrays. AFC models also indicate that ~ 20% of the average Tongariro magma comprises assimilated (meta)sedimentary basement material. Locally, Tongariro and adjacent Ruapehu volcanoes attain their most crust-like 87Sr/86Sr and 143Nd/144Nd compositions at ~ 100 and ~ 30 ka, paralleling with zircon model-age crystallisation modes at the rhyolitic Taupō volcano ~ 50 km to the NNE. These coincidences suggest that the timing and tempo of magma assembly processes at all three volcanoes were contemporaneous and may have been tectonically influenced since at least 200 ka.
CREB fusion–associated epithelioid mesenchymal neoplasms of the female adnexa: three cases documenting a novel location of an emerging entity and further highlighting an ambiguous misleading immunophenotype
Authors: Trecourt Alexis , Macagno Nicolas , Ngo Carine , Philip Charles-André , Lopez Jonathan , Ferreira Joana , Alves-Vale Catarina , Ray-Coquard Isabelle , Genestie Catherine , Agaimy Abbas , Devouassoux-Shisheboran Mojgan 
Published: April 2023

AbstractEWSR1/FUS-CREB-rearranged mesenchymal neoplasms are an emerging heterogeneous group of soft tissue tumors that encompasses low-grade lesions (angiomatoid fibrous histiocytoma/AFH) and a group of predominantly intra-abdominal aggressive sarcomas with epithelioid morphology and frequent keratin expression. Both entities occasionally harbor EWSR1::ATF1 fusions as alternate to the more frequent EWSR1/FUS::CREB1/CREM fusions. Although EWSR1/FUS-CREB-rearranged epithelioid malignant neoplasms have been described in diverse intra-abdominal sites, none involved the female adnexa. Herein, we describe three cases involving uterine adnexa in young females (41, 39, and 42-year-old); two associated with constitutional inflammatory symptoms. The tumors presented as a serosal surface mass of the ovary without parenchymal involvement (Case 1), as circumscribed nodule within ovarian parenchyma (Case 2), and as a periadnexal mass extending into the lateral uterine wall with lymph node metastasis (Case 3). They were composed of sheets and nests of large epithelioid cells with numerous stromal lymphocytes and plasma cells. The neoplastic cells expressed desmin and EMA, and variably WT1. One tumor expressed in addition AE1/AE3, MUC4, synaptophysin, chromogranin, and ALK. None expressed sex cord-associated markers. RNA sequencing identified EWSR1::ATF1 fusions in two cases and an EWSR1::CREM fusion in one. Exome-based RNA capture sequencing and clustering methods showed high transcriptomic proximity of tumor 1 with soft tissue AFH. This novel subset of female adnexal neoplasms should be included in the differential diagnosis of any epithelioid neoplasm involving female adnexa. Their aberrant immunophenotype can be misleading, underlining a wide spectrum of differential diagnosis.
Note on modular equations in the theory of signature 4
Authors: Kumar B. R. Srivatsa , Guruprasad P. S. , Udupa N. V. Sayinath , Raksha  
Published: April 2023

AbstractIn 2009, M. S. M. Naika et al. obtained Schl$$\ddot{a}$$

a
¨

fli type modular equations of degree 4. Motivated by their work, in the present work, we prove a class of modular equations in Ramanujan’s alternative theory of elliptic functions using theory of signature 4. In particular, the composite degrees of modular equations {1, 2, 4}, {1, 3, 9}, {1, 5, 25} and {1, 7, 49}.
Promoting physical activity among cancer survivors: an umbrella review of systematic reviews
Authors: Qiu Lin , Ye Maodie , Tong Yang , Jin Yongmei 
Published: April 2023

Abstract

Purpose
Exercise is the core element of rehabilitation for cancer patients. However, most of the patients’ exercise levels failed to meet the indicators recommended by the guidelines or even decreased. Therefore, this umbrella review aims to provide an overview of review articles addressing the evidence of interventions to promote physical activity behavior change and increase physical activity among cancer patients.

Methods
We searched nine databases from inception to 12 May 2022 to obtain systematic reviews and meta-analyses of interventions to promote physical activity among cancer patients. The AMSTAR-2 was used for the quality assessment.

Results
Twenty-six individual systematic reviews including 13 studies performed meta-analyses. A total of 16 studies’ designs were all in randomized controlled trial. Most reviews included studies that were mainly delivered in home settings. The most frequent and mean duration of the interventions was 12 weeks. Interventions mainly included electronic, wearable health technology-based, behavior change techniques (BCTs), and theory-based strategies.

Conclusions
Electronic, wearable health technology-based, BCTs, and theory-based interventions were effective and feasible in promoting physical activity in cancer survivors. Clinical practitioners should take corresponding intervention measures according to the characteristics of patients in different groups.

Implications for cancer survivors
Future research may benefit cancer survivors by more comprehensively applying electronic, wearable health technology-based, BCTs, and theory-based interventions.
Analyzing the potential of active learning for document image classification
Authors: Saifullah Saifullah , Agne Stefan , Dengel Andreas , Ahmed Sheraz 
Published: April 2023

AbstractDeep learning has been extensively researched in the field of document analysis and has shown excellent performance across a wide range of document-related tasks. As a result, a great deal of emphasis is now being placed on its practical deployment and integration into modern industrial document processing pipelines. It is well known, however, that deep learning models are data-hungry and often require huge volumes of annotated data in order to achieve competitive performances. And since data annotation is a costly and labor-intensive process, it remains one of the major hurdles to their practical deployment. This study investigates the possibility of using active learning to reduce the costs of data annotation in the context of document image classification, which is one of the core components of modern document processing pipelines. The results of this study demonstrate that by utilizing active learning (AL), deep document classification models can achieve competitive performances to the models trained on fully annotated datasets and, in some cases, even surpass them by annotating only 15–40% of the total training dataset. Furthermore, this study demonstrates that modern AL strategies significantly outperform random querying, and in many cases achieve comparable performance to the models trained on fully annotated datasets even in the presence of practical deployment issues such as data imbalance, and annotation noise, and thus, offer tremendous benefits in real-world deployment of deep document classification models. The code to reproduce our experiments is publicly available at https://github.com/saifullah3396/doc_al.
Virulence, antimicrobial resistance, and molecular characteristics of carbapenem-resistant Klebsiella pneumoniae in a hospital in Shijiazhuang City from China
Authors: Guo Yumei , Liu Faqiang , Zhang Yulan , Wang Xiaoli , Gao Weili , Xu Baohong , Li Yuxue , Song Ning 
Published: April 2023

Abstract
Carbapenem-resistant Klebsiella pneumoniae (CRKP), as one of the most common drug-resistant bacteria threatening human health, is hyper-resistant to multiple antimicrobial drugs and carbapenems, which can be dealt with only limited clinical treatment options. This study described the epidemiological characteristics of CRKP in this tertiary care hospital from 2016 to 2020. Specimen sources included blood, sputum, alveolar lavage fluid, puncture fluid, secretions from a burn wound, and urine. Among the 87 carbapenem-resistant strains, ST11 was the predominant isolate, followed by ST15, ST273, ST340, and ST626. These STs were in broad agreement with the STs defined by pulsed-field gel electrophoresis clustering analysis in discriminating clusters of related strains. Most CRKP isolates contained the blaKPC-2 gene, some isolates carried the blaOXA-1, blaNDM-1, and blaNDM-5 genes, and the isolates carrying carbapenem resistance genes were more resistant to the antimicrobials of β-lactams, carbapenems, macrolides, and fluoroquinolone. The OmpK35 and OmpK37 genes were detected in all CRKP strains, and the Ompk36 gene was detected in some CRKP strains. All detected OmpK37 had 4 mutant sites, and OmpK36 had 11 mutant sites, while no mutant sites were found in OmpK35. More than half of the CRKP strains contained the OqxA and OqxB efflux pump genes. The virulence genes were most commonly combined with urea-wabG-fimH-entB-ybtS-uge-ycf. Only one CRKP isolate was detected with the K54 podoconjugate serotype. This study elucidated the clinical epidemiological features and molecular typing of CRKP, and grasped the distribution of drug-resistant genotypes, podocyte serotypes, and virulence genes of CRKP, providing some guidance for the subsequent treatment of CRKP infection.
Insights into the primate trade into the European Union and the United Kingdom
Authors: Svensson Magdalena S. , Nijman Vincent , Shepherd Chris R. 
Published: April 2023

AbstractIllegal and/or unsustainable trade is a major obstacle to effective primate conservation. The wildlife trade in the European Union (EU) and the United Kingdom (UK) is significant, but for many species, such as primates, the trade is poorly understood and sparsely reported. All EU countries are Party to the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES); all primates are listed on Appendix I or II of CITES and are included on Annex A or B of Regulation (EC) No 338/97. We here combine data from several databases (CITES, UN Comtrade, TRAFFIC WiTIS) and seizure reports, to provide a narrative of the trade in primates into and within Europe. The legal import of live primates (2002–2021) amounted to 218,000–238,000 individuals (valued at US$ 869 million), with France, the UK, and Spain as the main importers and Mauritius, Vietnam, and China as the main exporters. Over 21,000 primate parts (trophies, skulls, bodies) were imported mainly from African countries, and UN Comtrade data suggests that ~ 600 tonnes of primate meat was imported mainly from Asia. The vast majority of live primates are either captive-born or captive-bred, and this proportion has increased over time. Reports of the illegal primate trade are far from complete, but the illegal trade of specific species or primate meat can have negative impacts of wild populations of already imperiled species. Stronger policies and more effective enforcement in consumer countries, such as the EU, would also aid in, and garner support for, better protecting primates in primate range states.
Revisiting the upper Visean mud mounds from Derbyshire (UK): the role of brachiopods in their growth
Authors: Carniti Alessandro P. , Della Porta Giovanna , Banks Vanessa J. , Stephenson Michael H. , Angiolini Lucia 
Published: April 2023

AbstractSeveral brachiopod-rich mud mounds occur in the upper Visean (Brigantian) of the Derbyshire Carbonate Platform succession in UK. The re-evaluation of the lithofacies architecture of a Derbyshire mud mound complex, developed in an intraplatform middle-ramp environment, led to the recognition of three lithofacies associations: (a) a 10 m thick basal unit of automicrite boundstone with siliceous sponge spicules and brachiopod–bryozoan packstone to wackestone beds; (b) a 10 m thick, 250 m wide, lens-shaped, convex-up massive core of clotted peloidal micrite and fenestellid bryozoan boundstone with sponge spicules; (c) inclined brachiopod–bryozoan–crinoid packstone flank beds. In the mud mound complex core, most of the carbonate mud with clotted peloidal and structureless micrite fabric is the result of biologically induced and influenced in-situ precipitation processes (automicrite). Brachiopods are not, as previously thought, limited to storm-scoured “pockets” in the mud mound complex core but are abundant and diverse in all lithofacies and lived on the irregular mud mound complex surface concentrating in depressions sustained by automicrite boundstone and the growth of bryozoans and sponges. The upper Visean Derbyshire mud mounds are, thus, representatives of a newly defined fenestellid bryozoan–brachiopod–siliceous sponge mud mound category, occurring in various middle–upper Visean Western European sites, a sub-type of the fenestellid bryozoan–crinoid–brachiopod Type 3 buildups of Bridges et al. (1995). These mud mounds, and other types of brachiopod-rich buildups, developed in carbonate platform settings between fair-weather and storm wave base, in dysphotic environments with dispersed food resources during the Visean. Brachiopod mud mound colonisation was favoured by moderate water depth, availability of food resources, and diverse substrates.
Tetrahydrocurcumin (THC) enhanced the clearance of Cryptococcus deneoformans during infection in vivo
Authors: He Tianli , Jin Zhiran , Hu Wei , Xia Xiaoxue , Li Donghui , Yao Weiyun , Li Guangnan , Zhou Xuefeng , Song Guoqiang 
Published: April 2023

AbstractCryptococcal species often cause lung infections and are the main cause of fungal meningitis. Claudin-4 appears to be a major structural component that maintains a tight alveolar barrier and prevents fluid and electrolyte leakage into the alveolar space. We aimed to determine whether S7-tetrahydrocurcumin (THC) could clearance of C. deneoformans and regulate claudin-4 expression during C. deneoformans infection. We investigated the effect of THC on C. deneoformans infection and its possible mechanism in vivo. Transmission electron microscopy was used to observe the ultrastructure of the lung tissue and the invasion of Cryptococcus. To clarify the effect of THC, we examined claudin-4, c-Jun, and Smad2 expression. We also measured claudin-4 expression in pulmonary specimens from clinical patients. THC reduced cryptococcal cell invasion in the lungs, improved alveolar exudation, and reduced inflammation. Pretreatment with THC suppressed c-Jun and Smad2 expression, resulting in significantly increased claudin-4 levels. In contrast, the expression of claudin-4 in clinical specimens from patients with cryptococcal infection was higher than that in normal specimens. THC enhanced the clearance of C. deneoformans during infection in vivo. We investigated the expression of claudin-4 and the possible mechanism of THC against C. deneoformans infection.
Tilapia aquaculture, emerging diseases, and the roles of the skin microbiomes in health and disease
Authors: Debnath Sanjit Chandra , McMurtrie Jamie , Temperton Ben , Delamare-Deboutteville Jérôme , Mohan Chadag Vishnumurthy , Tyler Charles R. 
Published: April 2023

AbstractAquaculture is playing an increasingly important role in global food security, especially for low-income and food-deficit countries. The majority of aquaculture production occurs in freshwater earthen ponds and tilapia has quickly become one of the most widely adopted culture species in these systems. Tilapia are now farmed in over 140 countries facilitated by their ease of production, adaptability to a wide range of environmental conditions, fast growth, and high nutritional value. Typically, tilapia have been considered a hardy, disease resilient species; however, the disease is increasing with subsequent threats to the industry as their production is intensified. In this review, we discuss tilapia production, with a focus on Bangladesh as one of the top producing countries, and highlight the problems associated with disease and treatment approaches for them, including the misuse of antimicrobials. We address a key missing component in understanding health and disease processes for sustainable production in aquaculture, specifically the role played by the microbiome. Here we examine the importance of the microbiome in supporting health, focused on the symbiotic microbial community of the fish skin mucosal surface, the abiotic and biotic factors that influence the microbiome, and the shifts that are associated with diseased states. We also identify conserved taxa of skin microbiomes that may be used as indicators of health status for tilapia offering new opportunities to mitigate and manage the disease and optimize environmental growing conditions and farming practices.
Informative Feedback and Explainable AI-Based Recommendations to Support Students’ Self-regulation
Authors: Afzaal Muhammad , Zia Aayesha , Nouri Jalal , Fors Uno 
Published: April 2023

AbstractSelf-regulated learning is an essential skill that can help students plan, monitor, and reflect on their learning in order to achieve their learning goals. However, in situations where there is a lack of effective feedback and recommendations, it becomes challenging for students to self-regulate their learning. In this paper, we propose an explainable AI-based approach to provide automatic and intelligent feedback and recommendations that can support the self-regulation of students’ learning in a data-driven manner, with the aim of improving their performance on their courses. Prior studies have predicted students’ performance and have used these predicted outcomes as feedback, without explaining the reasons behind the predictions. Our proposed approach is based on an algorithm that explains the root causes behind a decline in student performance, and generates data-driven recommendations for taking appropriate actions. The proposed approach was implemented in the form of a dashboard to support self-regulation by students on a university course, and was evaluated to determine its effects on the students’ academic performance. The results revealed that the dashboard significantly enhanced students’ learning achievements and improved their self-regulated learning skills. Furthermore, it was found that the recommendations generated by the proposed approach positively affected students’ performance and assisted them in self-regulation
Preferences for Types of Inclusive Family Violence Services Among LGBTQ People in Australia
Authors: Amos Natalie , Hill Adam O , Lusby Stephanie , Carman Marina , Parsons Matthew , McNair Ruth , Lyons Anthony , Bourne Adam 
Published: April 2023

Abstract
Purpose
LGBTQ people are less likely to seek support and face significant barriers in accessing affirmative family violence support services. Efforts to improve family violence service access must be grounded in the preferences of LGBTQ people themselves.

Method
Data from a large nationwide Australian survey of the health and wellbeing of LGBTQ adults were analysed. 4,148 participants expressed a preference for family violence service provision. Multivariable logistic regressions were used to identify factors associated with preferences for family violence service provision, comparing mainstream services that are not known to be inclusive, mainstream services that are known to be LGBTQ-inclusive, and LGBTQ-specific services.

Results
In total, 8.8% (n = 363) of participants indicated a preference for mainstream services, 57.5% (n = 2,383) for mainstream services that are known to be LGBTQ-inclusive and 33.8% (n = 1,402) for LGBTQ-specific services. Trans and non-binary identified people were more likely to prefer LGBTQ-specific services than cisgender participants, while bisexual, pansexual and asexual people were more likely to prefer mainstream LGBTQ-inclusive services. Participants with a regular general practitioner were more likely to prefer LGBTQ-inclusive services. Participants who had not felt supported the most recent time they reported an experience of family violence were more likely to prefer LGBTQ-specific services.

Conclusion
Family violence and healthcare services require training in LGBTQ issues to provide inclusive and affirming care. The findings have implications for policy and practice in family violence care and illustrate an urgent need to reform the current narrative of family violence, which frequently excludes LGBTQ communities.
A conceptual framework for sustainable waste management in small municipalities: the cases of Langebaan, South Africa and Swakopmund, Namibia
Authors: Kadhila Timoteus , de Wit Martin P. , Schenck Rinie 
Published: April 2023

AbstractMunicipal waste management is a major challenge for local governments in South Africa and Namibia, as in other developing countries. The circular economy concept in waste management is an alternative sustainable development framework that has the potential to combat resource depletion, pollution, and poverty while achieving the SDGs. The purpose of this study was to investigate the current waste management systems in Langebaan and Swakopmund municipalities resulting from municipal policies, procedures, and practices in the context of a circular economy. A mixed method approach was used to collect qualitative and quantitative data through structured in-depth interviews, document analyses, and direct observation. The study found that the Langebaan and Swakopmund municipalities have not yet fully implemented the circular economy concept into their waste management systems. A mix of waste consisting of papers, plastics, cans, tyres, and organic products is dumped into landfills weekly at a rate of about 85%. The main challenges to implementing the circular economy concept include: lack of technical solutions, inadequate regulatory frameworks, insufficient financial resources, lack of private sector involvement, insufficient human resource capacity, and inadequate information and knowledge. A conceptual framework was therefore proposed to guide the municipalities of Langebaan and Swakopmund in implementing the circular economy concept in their waste management systems.
Labellable Phylogenetic Networks
Authors: Francis Andrew , Steel Mike 
Published: April 2023

AbstractPhylogenetic networks are mathematical representations of evolutionary history that are able to capture both tree-like evolutionary processes (speciations) and non-tree-like ‘reticulate’ processes such as hybridization or horizontal gene transfer. The additional complexity that comes with this capacity, however, makes networks harder to infer from data, and more complicated to work with as mathematical objects. In this paper, we define a new, large class of phylogenetic networks, that we call labellable, and show that they are in bijection with the set of ‘expanding covers’ of finite sets. This correspondence is a generalisation of the encoding of phylogenetic forests by partitions of finite sets. Labellable networks can be characterised by a simple combinatorial condition, and we describe the relationship between this large class and other commonly studied classes. Furthermore, we show that all phylogenetic networks have a quotient network that is labellable.