bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infectious Complications of Targeted Therapies for Solid Cancers or Leukemias/Lymphomas
Authors: Pilmis Benoît , Kherabi Yousra , Huriez Pauline , Zahar Jean-Ralph , Mokart Djamel 
Published: March 2023

Background: Infections are well known complications of some targeted drugs used to treat solid organ cancer and hematological malignancies. Furthermore, Individual patient risk factors are associated with underlying pathologies, concomitant immunosuppressive treatment, prior treatment and use of anti-infective prophylaxis. Immune-related adverse events (irAEs) are frequent among patients treated with new targeted drugs. Objectives: In this narrative review, we present the current state of knowledge concerning the infectious complications occurring in patients treated with immune checkpoint inhibitors (ICIs), Bruton’s tyrosine kinase (BTK) inhibitors, phosphatidylinositol 3-kinase (PI3K) inhibitors, antiapoptotic protein BCL-2 inhibitors, Janus kinase inhibitors or CAR-T cell infusion. Sources: We searched for studies treating infectious complications of ICIs, BTK inhibitors, PI3K inhibitors, antiapoptotic protein BCL-2 inhibitors and CAR-T cell therapy. We included randomized, observational studies and case reports. Content: Immune-related adverse events (irAEs) are frequent among patients treated with new targeted drugs. Treatment of irAEs with corticosteroids and other immunosuppressive agents can lead to opportunistic infections. Bruton’s tyrosine kinase (BTK) inhibitors are associated with higher rate of infections, including invasive fungal infections. Implications: Infections, particularly fungal ones, are common in patients treated with BTK inhibitors even though most of the complications occurring among patients treated by ICIs or CART-cells infusion are associated with the treatment of side effects related to the use of these new treatments. The diagnosis of these infectious complications can be difficult and may require extensive investigations.
Novel Insights in the Potential of Halogenated Polyketide–Peptide Molecules as Lead Compounds in Cancer Drug Discovery
Authors: Pellicioni Valentina , Esposito Germana , Greco Giulia , Cruz-Chamorro Ivan , Ferrini Fabio , Sestili Piero , Teta Roberta , Fimognari Carmela , Costantino Valeria 
Published: March 2023

In this interdisciplinary study, we selected two compounds, namely, smenamide A, a peptide–polyketide, and smenolactone D, a polyketide, as models because they are representative of two different classes of molecules isolated from the marine sponge Smenospongia aurea. The organic extract of Smenospongia aurea was analyzed using a combination of high-resolution LC-MS/MS and molecular networking, a recently developed method for automated LC-MS data analysis. The analyses were targeted to highlight clusters made by chlorinated compounds present in the extracts. Then, the two model compounds were analyzed for their bioactivity. Data reported here show that smenamide A did not exhibit a cytotoxic effect, while smenolactone D was cytotoxic on different tumor cell lines and was able to induce different types of cell death, including ferroptosis and apoptosis.
Differential Susceptibility of Coleomegilla maculata and Scymnus creperus Larvae to Aggression by Solenopsis invicta Workers
Authors: Riddick Eric W. , Wu Zhixin , Chen Jian 
Published: March 2023

The biological control of aphids by aphidophagous coccinellids is often hampered by aphid-tending ants or aggressive, invasive ants foraging for food. Aggressive species such as the imported fire ant Solenopsis invicta Buren may attack and kill coccinellid larvae. This study tested the hypothesis that wax-secreting Scymnus creperus Mulsant larvae are less susceptible than non-wax-secreting Coleomegilla maculata (DeGeer) larvae to S. invicta aggression. Laboratory experiments were set up using bird cherry-oat aphid Rhopalosiphum padi (L.) nymphs and adults (as prey for coccinellids) on barley leaves in arenas with either coccinellid species and with or without S. invicta workers. The presence of S. invicta reduced aphid predation by C. maculata but not Sc. creperus. The frequency of S. invicta attack was greater for C. maculata than Sc. creperus; mortality was significantly greater for C. maculata than Sc. creperus. The wax covering on Sc. creperus reduced S. invicta aggression. Unexpectedly, Sc. creperus larvae with the wax cover removed did not suffer more S. invicta attacks or increased mortality. In conclusion, the wax cover and, perhaps, the volatile or non-volatile compounds in the wax and on the integument of Sc. creperus larvae reduce S. invicta aggression. Further research could identify the wax compounds and determine their functionality as semiochemicals against S. invicta.
D-Wave Superconducting Gap Symmetry as a Model for Nb1−xMoxB2 (x = 0.25; 1.0) and WB2 Diborides
Authors: Talantsev Evgeny F. 
Published: March 2023

Recently, Pei et al. (National Science Review2023, nwad034, 10.1093/nsr/nwad034) reported that ambient pressure β-MoB2 (space group: R3¯m) exhibits a phase transition to α-MoB2 (space group: P6/mmm) at pressure P~70 GPa, which is a high-temperature superconductor exhibiting Tc=32 K at P~110 GPa. Although α-MoB2 has the same crystalline structure as ambient-pressure MgB2 and the superconducting critical temperatures of α-MoB2 and MgB2 are very close, the first-principles calculations show that in α-MoB2, the states near the Fermi level, εF, are dominated by the d-electrons of Mo atoms, while in MgB2, the p-orbitals of boron atomic sheets dominantly contribute to the states near the εF. Recently, Hire et al. (Phys. Rev. B2022, 106, 174515) reported that the P6/mmm-phase can be stabilized at ambient pressure in Nb1−xMoxB2 solid solutions, and that these ternary alloys exhibit Tc~8 K. Additionally, Pei et al. (Sci. China-Phys. Mech. Astron. 2022, 65, 287412) showed that compressed WB2 exhibited Tc~15 K at P~121 GPa. Here, we aimed to reveal primary differences/similarities in superconducting state in MgB2 and in its recently discovered diboride counterparts, Nb1−xMoxB2 and highly-compressed WB2. By analyzing experimental data reported for P6/mmm-phases of Nb1−xMoxB2 (x = 0.25; 1.0) and highly compressed WB2, we showed that these three phases exhibit d-wave superconductivity. We deduced 2Δm(0)kBTc=4.1±0.2 for α-MoB2, 2Δm(0)kBTc=5.3±0.1 for Nb0.75Mo0.25B2, and 2Δm(0)kBTc=4.9±0.2 for WB2. We also found that Nb0.75Mo0.25B2 exhibited high strength of nonadiabaticity, which was quantified by the ratio of TθTF=3.5, whereas MgB2, α-MoB2, and WB2 exhibited TθTF~0.3, which is similar to the TθTF in pnictides, A15 alloys, Heusler alloys, Laves phase compounds, cuprates, and highly compressed hydrides.
Complicaciones postoperatorias en fractura de órbita: experiencia en el Hospital del Trabajador de Santiago
Authors: Andrades Cvitanic Patricio , Grass Briones Bastián , Zang Jonathan , Rios Vergara Marcos , Rodriguez Schneider Diego , Borel Baeza Claudio 
Published: March 2023

Objetivo: Describir la experiencia del equipo de cirugía maxilofacial del Hospital del Trabajador en el manejo de las fracturas de órbita.Materiales y método: Estudio retrospectivo de 42 pacientes consecutivos operados por fractura de órbita en el Servicio de Cirugía Maxilofacial del Hospital del Trabajador entre enero de 2016 y diciembre de 2017. Se tabularon datos demográficos, información del trauma, tipo de fractura, fracturas asociadas, tratamiento y seguimiento. Resultado: De los 42 pacientes, la mayoría eran hombres (73,8%) con edad promedio de 40±12,24 años. Los principales síntomas al ingreso fueron equimosis (64,3%), edema periocular (54,8%), hemorragia subconjuntival (33,3%) y diplopía (26,2%). La pared orbitaria más frecuentemente afectada fue el piso de la órbita (85,7%). Las fracturas se presentaron de forma aislada en 35,7% de los casos y asociada a otra fractura de la cara en 64,3%. Post cirugía, la tasa de complicación fue de 16,7%, producto de diplopía y enoftalmos leves que solo requirieron tratamientos conservadores para su resolución. Discusión: La baja tasa de complicaciones se debe a la experiencia del equipo médico con un seguimiento a largo plazo, la medición de volúmenes orbitarios, imagenología intraoperatoria, utilización de malla prefabricada y asistencia endoscópica.Conclusiones: Un adecuado diagnóstico y evaluación son fundamentales para el tratamiento de la fractura de órbita. Los datos demográficos, las características de las fracturas y las complicaciones descritas fueron muy similares a lo reportado por otras experiencias, mientras que la tasa de complicaciones fue menor.
Growth of (100) β-Ga2O3 single crystal by controlling the capillary behaviors in EFG system
Authors: Shin Yun-Ji , Lim Su-Min , Jeong Woon-Hyeon , Cho Seong-Ho , Choi Mee-Hi , Lee Won-Jae , Jeong Seong-Min , Bae Si-Young 
Published: March 2023

Abstract
In this study, a numerical simulation of edge-defined film-fed growth (EFG) was performed to determine the appropriate capillary conditions for Ga2O3 melt. Meniscus and capillary rise were significantly influenced by the design of the die in the EFG system. The ratio of the seed crystal and die width was >0.73 for a die width of 4.4 mm. Narrower slit width resulted in higher capillary rise with longer process time compared with wider slit width. Under conditions consistent with the simulation results, highly crystalline (100) β-Ga2O3 single crystals were successfully achieved.
In situ electrical monitoring of SiO2/Si structures in low-temperature plasma using impedance spectroscopy
Authors: Morozumi Junki , Goya Takahiro , Kuyama Tomohiro , Eriguchi Koji , Urabe Keiichiro 
Published: March 2023

Abstract
To investigate the electrical properties and degradation features of dielectric materials during plasma exposure, we developed an in situ impedance spectroscopy (IS) system. We applied the proposed system to monitor SiO2/Si structures exposed to Ar plasma. By analyzing the measured data based on an equivalent circuit model considering the plasma and SiO2/Si structures, we obtained the resistance (R) and capacitance (C) values for the SiO2 film and SiO2/Si interface. In a cyclic experiment of in situ IS and high-energy ion irradiation, we characterized dielectric degradation by ion irradiation based on the variations in the R and C values of the SiO2 film. A continuous in situ IS measurement revealed temporal variations in the electrical properties of the film and interface independently. The thickness-dependent degradation observed for the RC variation was analyzed and compared with the results of previous ex situ measurement studies. This study demonstrates that the in situ IS measurement technique is promising for monitoring plasma-assisted dry processes.
On modules over the mod 2 Steenrod algebra and hit problems
Authors: Võ Phúc Đặng 
Published: March 2023

<p>Let us consider the prime field of two elements, $\mathbb F_2.$ The classical "hit problem" in Algebraic Topology, which is widely considered to be an important and fascinating open problem that has yet to be resolved, asks for a minimal set of generators for the polynomial algebra, $\mathcal P_m:=\mathbb F_2[x_1, x_2, \ldots, x_m]$, on $m$ variables $x_1, \ldots, x_m$, each of which has degree one, regarded as a connected unstable $\mathscr A$-module. The algebra $\mathcal P_m$ is the cohomology with $\mathbb F_2$-coefficients of the product of $m$ copies of the Eilenberg-MacLan complex $K(\mathbb F_2, 1)$. Despite extensive study over the past three decades, the hit problem remains unresolved for $m\geq 5$. </p>
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<p>In this article, we develop our previous work [Commun. Korean Math. Soc. \textbf{35} (2020), 371-399] on the hit problem for $\mathscr A$-module $\mathcal P_5$ in the generic degree $n_s = 5(2^{s}-1) + 18.2^{s}$ with $s$ an arbitrary non-negative integer. As a consequence, a localized variation of the Kameko conjecture, which concerns the dimension of the cohit space $\mathbb F_2\otimes_{\mathscr A}\mathcal P_m$ in relation to parameter vectors, has been claimed to be veracious in the instance where $m = 5$ and the degree is $n_s.$ Also, we show that this conjecture also holds for any $m\geq 1$ and degrees $\leq 12.$ This study has two important applications: (1) it establishes the dimension result for the cohit space $\mathbb F_2\otimes_{\mathscr A}\mathcal P_m$ for $m = 6$ in the generic degree $5(2^{s+4}-1) + n_1.2^{s+4}$ with $s > 0;$ and (2) it describes the representations of the general linear group of rank $5$ over $\mathbb F_2.$ As a result, we prove that the algebraic transfer, defined by W. Singer [Math. Z. \textbf{202} (1989), 493-523], is an isomorphism in bidegrees $(5, 5+n_s)$ with $s\geq 0.$ Besides, we obtain new results on the behavior of this algebra transfer for all homological degrees $m$. Specifically, we demonstrate that Singer's transfer is a trivial isomorphism in bidegree $(m, m+12)$ for any $m > 0$.</p>
EEG-to-EEG: Scalp-to-Intracranial EEG Translation using a Combination of Variational Autoencoder and Generative Adversarial Networks
Authors: Abdi-Sargezeh Bahman , valentin antonio , Alarcon Gonzalo , Sanei Saeid 
Published: March 2023

<p>A generative adversarial network (GAN) enables mapping a data sample from one domain to another one. It has extensively been employed in image-to-image and text-toimage translation. We propose an EEG-to-EEG translation model based on a GAN structure in which a conditional GAN (cGAN) is combined with a variational autoencoder (VAE), named as VAE-cGAN. Scalp EEG (sEEG) is plagued by noise and suffers from low resolution. On the other hand, intracranial EEG (iEEG) recordings enjoy high resolution. Here, we consider the task of mapping the sEEG to iEEG to enhance the sEEG resolution. <br>
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Investigation of the main (10) causes of infertility in women (Epidemiological study in Baghdad)
Authors: J. Hasan Baqer , Fadhil Zainab , Oneeis Souhayla 
Published: March 2023

The research demonstrated to epidemiological field study about the causes of infertility in women, where infertility affects the female’s life physically and psychologically and this study aims to uncover the causes of infertility, infertility can be divided into two types, temporary and permanent infertility, and our study showed that infertility might be an epidemic that’s spread through the whole province of Baghdad and we found that out through our visits to doctors in all Baghdad’s areas for two consecutive months and we collected 9860 samples and we made two tables explaining the causes of infertility and we found out that the main cause was hormonal disturbances with 21.64%, Cystic ovaries took the second place as the second most common cause with 18.5% and the least common cause was tubal obstruction with 2.25% and we conclude that infertility is a dangerous epidemic that we all should be more aware and careful.
Alternative Treatment of Bacterial Wound Infections
Authors: Motaweq Zahraa Yosif , Majeed Al Rufaie Mohauman Mohammad 
Published: March 2023

Topical and systemic antibiotic treatment are essential in the prevention and treatment of wound infections. Systemic antibiotics, on the other hand, are strongly linked to mechanisms of resistance, which jeopardize the treatment process. The direction of systemic antibiotics to the eschar becomes less reliable the deeper the burn and the thicker the eschar becomes for local wound care . As a result, topical antibiotics appear as a viable treatment option, as they help to maintain a “high and sustained concentration of the antimicrobial at the infection site.
Every year, wound treatment develops a high urgent clinical problem, as The requirement for wound care has an influence on a significant percentage of the global population. The system of healthcare in the United States spends $20 million a year on wounds . An Incisional, acute, and chronic wounds are all examples of wounds that can become infected and lead to more complications.
Incisional wounds and deep lacerations are often troublesome, and they account for a significant portion of the annual cost of wound healing products. While Wounds from incisions heal more quickly than chronic wounds, they always have challenges with appropriate closure as well as the formation of granulation tissue, which might lower one's quality of life. Wounds from incisions are also susceptible to infection, necessitating further care. Antiseptics, antibiotics, as well as silver dressings have traditionally is always used to treat wounds, however each of these therapies is ineffective against a wide range of microorganisms often present in wounds.
The genesis of architecture and civil construction in Poland as a base for housing for soldiers
Authors: KOŚCIELECKI Tomasz , BARYŁKA Adam 
Published: March 2023

This article presents a problem that, on a daily basis, seems to be imperceptible to unfamiliar people. It outlines the issue of accommodation for soldiers of the Armed Forces of the Republic of Poland and describes how the issue was dealt with in the past. Having a place to live is one of the most important factors for a person. The fulfillment of this condition significantly influences the sense of his / her security - the second most important need of every individual.
Technical safety of buildings around polish quarries against harmful seismic vibrations caused by rock blasting
Authors: Chrzan Tadeusz , SOBOTKA Jerzy 
Published: March 2023

This paper presents the results of measurements of the elliptical distribution of seismic vibrations generated during rock blasting.The technical safety of a building in the area of seismic vibrations is determined by the vibration velocity that does not exceed the line B included in zone II of the scale of dynamic influences [SWD]. The hypothesis proved in the paper is that for both elliptical and circular distributions of the vibration velocity in rock mining with blasting material [BM] there is a directionality of the horizontal radial component Vx and the tangential component Vy of the vibration velocity.The magnitude of the components Vx and Vy of the vibration velocity at the same distance from the vibration source depends on the directional angle "α" between the line of the blast holes and the line connecting the centre of the surface of the rock block being mined with [BM] and the place of measurement. The elliptical shapes of the graphs Vx and Vy obtained during the mining of the BM of the basalt deposit, which depend on the value of the directional angle, were compared with the shape of the circular velocity graphs Vx and Vy. New correlations are given that take into account the directional angle when calculating the maximum vibration velocity values needed to determine the damage caused to a bulding by the SWD.A dynamic impact scale [SWD] for the assessment of building damage as the vibration velocity acting on the building increases is given and discussed. Vibration velocity diagrams measured during the excavation of BM rock are presented for circular distributions in accordance with theoretical predictions. A vibration velocity diagram for an elliptical distribution, inconsistent with a circular distribution, measured during the excavation of BM rock is presented. It is shown that the directionality of the horizontal radial and tangential components of vibration velocity exists for both circular and elliptical distribution of vibration velocity in rock excavation with BM. In the conclusions, for the elliptical velocity field of the vibrations, the conditions to be observed in order to be able to direct the smallest vibrations towards the built up area are given.
Revising Properties of Planet–Host Binary Systems. III. There Is No Observed Radius Gap for Kepler Planets in Binary Star Systems*
Authors: Sullivan Kendall , Kraus Adam L. , Huber Daniel , Petigura Erik A. , Evans Elise , Dupuy Trent , Zhang Jingwen , Berger Travis A. , Gaidos Eric , Mann Andrew W. 
Published: March 2023

Abstract
Binary stars are ubiquitous; the majority of solar-type stars exist in binaries. Exoplanet occurrence rate is suppressed in binaries, but some multiples do still host planets. Binaries cause observational biases in planet parameters, with undetected multiplicity causing transiting planets to appear smaller than they truly are. We have analyzed the properties of a sample of 119 planet-host binary stars from the Kepler mission to study the underlying population of planets in binaries that fall in and around the radius valley, which is a demographic feature in period–radius space that marks the transition from predominantly rocky to predominantly gaseous planets. We found no statistically significant evidence for a radius gap for our sample of 122 planets in binaries when assuming that the primary stars are the planet hosts, with a low probability (p < 0.05) of the binary planet sample radius distribution being consistent with the single-star population of small planets via an Anderson–Darling test. These results reveal demographic differences in the planet size distribution between planets in binary and single stars for the first time, showing that stellar multiplicity may fundamentally alter the planet formation process. A larger sample and further assessment of circumprimary versus circumsecondary transits is needed to either validate this nondetection or explore other scenarios, such as a radius gap with a location that is dependent on binary separation.