bluuebunny/crossref_metadata_2025_split huggingface dataset:
studi kasus KEKERASAN TAJAM DENGAN CIDERA VASKULER PADA TIGA KASUS PEMBUNUHAN
Authors: Yanuarti Ainun Fahmi , Suciningtyas Martiana 
Published: January 2025

PENDAHULUAN
Pembunuhan dengan kekerasan tajam merupakan salah satu penyebab kematian utama di beberapa negara. Kekerasan tajam dapat disertai dengan cidera vaskuler pada pembuluh darah yang tanpa adanya pertolongan segera seringkali berakhir pada kematian. Berikut akan didiskusikan tiga kasus pembunuhan dengan kekerasan tajam yang melibatkan cidera vaskuler dan berakhir kematian.
MATERIAL DAN METODE
Materi diskusi berupa tiga kasus pembunuhan dengan kekerasan tajam yang melibatkan cidera vaskuler di Yogyakarta. Kasus pertama adalah laki-laki dengan luka tusuk pada paha kiri, pada pemeriksaan dalam didapatkan srteri dan vena femoralis dalam keadaan terpotong. Kasus kedua adalah seorang laki-laki dengan dua luka bacok pada paha kanan, satu luka pada tungkai bawah kanan dan satu luka bacok pada tungkai bawah kiri. Dari uji bilas pembuluh nadi kanan didapatkan kebocoran pada pembuluh darah tungkai bawah kanan sisi belakang. Kasus ketiga merupakan seorang perempuan dengan beberapa luk tusuk: empat pada leher, satu pada dada kiri, satu pada punggung kiri dan satu pada lengan atas kanan serta satu luka iris pada siku kiri. Dari pemeriksaan dalam terlihat bahwa arteri carotis interna terpotong.
KESIMPULAN
Ketiga kasus memiliki pola luka seperti ciri-ciri luka dalam pembunuhan yakni luka bisa terjadi di sembarang area tubuh, dijumpai luka tangkis dan kerusakan pakaian. Cidera vaskular yang terlibat pada ketiga kasus menghasilkan mekanisme kematian yang sama, yakni perdarahan masif.
Authors: Shofiyulloh M. , Munandar Arif , Wardati Khurul 
Published: January 2025

ABSTRAK. Graf prima koprima atas grup hingga merupakan representasi grup hingga pada graf dengan memandang anggota grup sebagai vertek dari graf dan dua vertek berbeda dan adjacent jika dan hanya jika order dan order adalah bilangan prima atau saling prima. Penelitian ini mengkaji bagaimana karakterisasi graf prima koprima atas grup dihedral. Melalui analisis terhadap pola yang muncul pada graf yang terbentuk, dapat ditemukan sifat sifat dari graf prima koprima atas grup dihedral yang berkaitan dengan karakterisasi graf komplit dan graf Hamilton. Kemudian, penelitian ini diakhiri dengan pembahasan konektivitas vertek pada graf prima koprima atas grup dihedral.
Identifikasi dan Upaya Pemenuhan Kebutuhan Informasi Terkait Pemeliharaan Kesehatan Reproduksi Remaja Melalui Kegiatan Edukasi pada Siswa Sebuah SMP di Kabupaten Cilacap
Authors: Widiartini Catharina , Pribadi Fajar Wahyu , Sutasman Thomas , Kuncoro Prasetyo Tri , Setiawan Agus Budi 
Published: January 2025

Meningkatnya permasalahan kesehatan reproduksi remaja akibat dampak buruk pajanan internet selama masa pembelajaran daring perlu mendapat perhatian kita bersama. Hal ini diperburuk oleh tertutupnya jalur komunikasi dengan orang tua akibat pandangan bahwa pembicaraan kesehatan reproduksi merupakan hal tabu. Permasalahan ini pun relevan bagi SMP Pius, Cilacap, Jawa Tengah. Upaya identifikasi kebutuhan pengetahuan mengenai berbagai aspek kesehatan reproduksi bagi para siswa mengawali langkah selanjutnya berupa kegiatan edukasi. Sebanyak 80 siswa kelas 8 dan 65 siswa kelas 9 (total 145 siswa), dengan rerata usia 13,3 tahun mengikuti kegiatan ini. Penyampaian materi terkait aspek biologis, psikologis dan sosial kesehatan reproduksi remaja dilaksanakan secara langsung melalui ceramah, diskusi interaktif, games dan menonton video edukasi, serta secara tertulis melalui modul yang dibagikan. Rerata persentase siswa yang menjawab benar pada pre-test sebesar 74,31 % dan pada post-test sebesar 74,92%. Terdapat peningkatan pengetahuan siswa pasca pelaksanaan kegiatan yang ditunjukkan dengan adanya peningkatan nilai minimal dan maksimal serta modus pada post-test. Tingkat pengetahuan siswa pada 15 sub topik kesehatan reproduksi memadai, sedangkan pada 10 sub topik kesehatan reproduksi kurang kurang memadai. Kegiatan selanjutnya dapat memprioritaskan upaya peningkatan pengetahuan siswa yang kurang memadai pada beberapa aspek tersebut. Kegiatan ini perlu dirutinkan dengan memperluas sasaran melalui peningkatan kapasitas guru sebagai fasilitator dan narasumber dalam diskusi masalah kesehatan reproduksi remaja dengan siswa.
Pemeriksaan Glukosa Darah Dan Kolesterol Serta Penyuluhan Kesehatan Tentang Hiperkolesteronemia dan Komplikasi Diabetes Mellitus Pada Warga Dengan Overweight Dan Obesitas Di Desa Kalibagor, Kecamatan Kalibagor, Kabupaten Banyumas
Authors: Wahyudin Wahyudin , Arjadi Fitranto , Setyanto Muhamad Rifqi , Pauzi Rizqi Yanuar , Riyanto Slamet , Saad Nursan 
Published: January 2025

Overweight dan obesitas telah menjadi masalah kesehatan global yang serius, termasuk di Indonesia. Kondisi ini tidak hanya mempengaruhi penampilan fisik, tetapi juga meningkatkan risiko berbagai penyakit kronis, seperti diabetes mellitus dan penyakit jantung. Pemeriksaan glukosa darah dan kolesterol secara berkala merupakan langkah penting dalam deteksi dini diabetes mellitus dan hiperkolesteronemia. Diabetes mellitus, suatu kondisi di mana tubuh tidak dapat memproduksi atau menggunakan insulin dengan baik, dapat menyebabkan berbagai komplikasi serius jika tidak ditangani dengan tepat, seperti kerusakan ginjal, saraf, dan penglihatan. Pengabdian masyarakat yang dilakukan yaitu pemeriksaan GDS dan kolesterol total kemudian dilanjutkan dengan penyuluhan kesehatan tentang hiperkolesteronemia dan komplikasi diabetes mellitus. Hasil pemeriksaan diperoleh sebagian besar warga yang hadir mengalami overweight dan obesitas sebanyak 70%, dan sisanya mempunyai berat badan yang normal, yang mengalami diabetes sebanyak 12%. Peningkatan kesadaran masyarakat tentang pentingnya menjaga berat badan dalam rentang normal, bersama dengan pola hidup sehat, dapat membantu menurunkan prevalensi penyakit metabolik di masa depan.
KORELASI USIA DAN JENIS KELAMIN DENGAN GRADING LIMFOMA NON HODGKIN SEL B DI RSUD PROF. DR. MARGONO SOEKARJO PURWOKERTO
Authors: Pangestu Thomas Adi , Sulistyo Hidayat , Djatmiko Wahyu , Novrial Dody , Mardhihusodo Hajid Rahmadianto 
Published: January 2025

Latar Belakang: Limfoma non-Hodgkin (LNH) dibedakan menjadi dua kelompok utama, yaitu limfoma sel B dan limfoma sel T/NK. Tipe LNH paling banyak di dunia adalah LNH sel B. Salah satu cara mengelompokkan LNH sel B yaitu dengan menggunakan pemeriksaan histopatologi untuk membedakan grading menjadi low grade dan high grade. Tingkat kejadian LNH sel B meningkat bertahap berdasarkan usia dan lebih banyak terjadi pada laki-laki. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara usia dan jenis kelamin dengan grading LNH sel B. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional yang dilakukan pada pasien limfoma non-Hodgkin sel B di RSUD Prof. Dr. Margono Soekarjo Purwokerto pada tahun 2019-2021. Analisis data menggunakan uji Chi-square. Hasil: Total sampel yang didapatkan adalah 75 pasien LNH sel B. Sebanyak 47 (62,7%) pasien berusia <60 tahun dan 28 (37,3%) pasien berusia ⩾60 tahun. Pasien laki-laki berjumlah 40 (53,3%) pasien, lebih banyak daripada perempuan yang berjumlah 35%. Hasil analisis menunjukkan bahwa tidak terdapat hubungan antara usia dengan grading (p=0,617), serta jenis kelamin dengan grading (p=0,366). Kesimpulan: Tidak terdapat hubungan antara usia dengan grading LNH sel B. Tidak terdapat hubungan antara jenis kelamin dengan grading LNH sel B.
Parental Factors Associated With Measles–Mumps–Rubella Vaccination in US Children Younger Than 5 Years
Authors: Zhou Eric Geng , Cantor Jonathan , Gertz Autumn , Elbel Brian , Brownstein John S. , Rader Benjamin 
Published: January 2025

Objectives. To determine the association between parental characteristics and MMR (measles–mumps– rubella) vaccination status of children in the United States. Methods. We conducted a cross-sectional study from July 2023 to April 2024 using a digital health survey via OutbreaksNearMe, weighted to target national population characteristics. We analyzed the responses of 19 892 parents of children younger than 5 years to examine the association between self-reported parental characteristics (i.e., sociodemographics, politics, COVID-19 vaccination status) and children’s MMR vaccination rates using logistic regression. Results. Children of parents who received at least 1 dose of the COVID-19 vaccine had higher MMR vaccination rates (80.8%) than did children of unvaccinated parents (60.9%; odds ratio [OR] = 1.84; 95% confidence interval [CI] = 1.68, 2.00). We observed lower MMR vaccination rates among children of parents who identified as Republican versus Democratic (OR = 0.73; 95% CI = 0.64, 0.82), parents on Medicaid or Medicare versus private insurance (OR = 0.85; 95% CI = 0.76, 0.95), and minority (OR = 0.44) versus White (OR = 0.71) parents. We found higher MMR vaccination rates in the Northeast and Midwest United States. Conclusions. Early data indicate that parental sociodemographic characteristics and COVID-19 vaccine status are associated with children’s MMR vaccine uptake, emphasizing the need for further investigations into multipronged public health interventions. ( Am J Public Health. 2025;115(3):369–373. https://doi.org/10.2105/AJPH.2024.307912 )
Emerging trends and hot spots in epigenetic modifications in neurology: A bibliometric analysis
Authors: Xu Shu-Ying , Zhang Siyao , Zeng Chun-Li , Peng Yong-Jun , Xu Min 
Published: January 2025

Abstract

This study employs a bibliometric analysis to examine the evolution and future trajectories in epigenetic modifications in neurology from 2004 to 2024. A total of 12,964 publications were scrutinized via the R bibliometrix package and VOSviewer for network visualization, complemented by Scimagp Graphica to elucidate global collaborative networks. Our extensive review reveals a significant growth in the field of epigenetic neurology studies, driven by an increased output of publications and evidenced by an enhanced focus on epigenetic modifications. The United States and McGill University are recognized as central contributors, with Nature leading as the most prolific journal and J. Mill and E.J. Nestler distinguishing themselves as key authors by publication volume and citation impact, respectively. A detailed keyword analysis highlighted "expression," "DNA methylation," "brain," "gene-expression," and "gene" as the most recurrent terms, indicating core areas of research concentration. Subsequent manual analysis due to software-detected inaccuracies reaffirmed Alzheimer's disease, cancer, and schizophrenia as predominant neurological diseases associated with epigenetic studies. Pathophysiological processes such as DNA methylation, oxidative stress, and synaptic plasticity have been extensively examined in relation to epigenetic modifications in neurology. Synthesis of the reference literature analysis identifies critical themes such as the role of glucocorticoid receptors, the significance of hydroxymethylcytosine in neural DNA, the implications of epigenetic patterns in mental health, and the impact of BDNF gene on memory consolidation. These insights into epigenetic research in neurology indicate a sustained and intensifying trajectory, hinting at expanding horizons for future therapeutic approaches and interventions. Our findings underscore an active and progressing interest in neurological epigenetics, suggesting a continued expansion and specialization in the exploration of epigenetic mechanisms and their clinical relevance.
An ‘Invisible Nerve’ To Block: A Regional Anaesthesia Block Conundrum of Sciatic Nerve for Above-Knee Amputation in A High-Risk Patient
Authors: Baththirange Malaka Munasinghe , Jayasuriya NJASS 
Published: January 2025

Abstract

Background
Above-knee amputation (AKA) under regional anaesthesia alone can pose multiple challenges to anaesthetists. For AKA, ultrasound-guided selective sciatic nerve, posterior femoral cutaneous nerve (PFCN), femoral, lateral femoral cutaneous, and obturator nerve blockade provide satisfactory anaesthesia.
Case Presentation
A 52-year-old woman with ischemic heart disease, atrial fibrillation on therapeutic anticoagulation, chronic kidney disease stage 3, poorly controlled diabetes mellitus, anaemia, and heart failure (ejection fraction 25–30%) was scheduled for an urgent left AKA under regional anaesthesia block due to ascending infection. Considering the high risk, a suprainguinal fascia iliaca block with a perineural catheter was performed under ultrasound. Visualisation of the sciatic nerve and the PFCN was unsuccessful as the neurosonoanatomy was undetectable. The motor response using a nerve stimulator to the suspected sciatic nerve failed, too. 0.5% levobupivacaine 20ml was administered in the area of the suspected nerves using piriformis and other sonoanatomical landmarks. Amputation was carried out without additional analgesia or sedation. Intraoperatively, the sciatic nerve was found to be distorted macroscopically due to liquefactive necrosis. Postoperatively in HDU, her pain control was satisfactory with perineural infusion.
Conclusions
The inability to identify the sciatic nerve due to liquefaction is a peculiar encounter in this patient. Still, it hints at an unusual cause for difficult peripheral nerve visualisation and stimulation. Due to the fact that the sciatic and PFCN lie closer when they exit the sciatic foramen under piriformis, a sufficient volume of local anaesthetic during sciatic nerve block may spread around and anaesthetise PFCN.
Production objectives of smallholder farmers: Implications on beef value chain in livestock development programmes
Authors: Muteyo Enock , Gift Chomuzinda 
Published: January 2025

Abstract

In this current context of production objectives which has shifted from pro commercial to one that is largely dominated by the small to medium cattle producers a case study in beef agro- ecological zones was conducted in Gokwe South and Mount Darwin, two administrative districts in Zimbabwe, to assess its effectiveness in beef value chain (BVC) in livestock development programmes. A total of 100 respondents were randomly drawn from the two districts three villages from Gokwe South and six from Mount Darwin. A structured questionnaire was developed and pretested to ensure that the questions were properly developed and structured. The tool was uploaded on Kobo, a data collection Kit and administered by well-trained enumerators. Key modules of the collected Data included biodata, profiling production systems, objectives of keeping animals, constraints in the production systems, marketing practices, herd dynamics and adaptive mechanism. Data was analyzed by SPSS version 23. The findings showed that smallholder beef farmers in the surveyed districts practice subsistence farming prioritized keeping cattle for draught power, and as a moving bank which also has a positive bearing on their socio-economic status. The study also noticed that breeding was rarely practiced thou pen-fattening was popular production systems among farmers. The marketing of the cattle was random and opportunistic, mainly to solve immediate family problems, with a small niche of farmers adopting business models such as pen fattening. Natural grazing was identified as the main source of feed, with minimal to no rangeland management system in use such as paddocking, this exposed the farmers to seasonal drought risks. Farmers highlighted challenges which they encountered, these ranged from lack of technical know-how due to limited access to advice from extension workers/experts, lack of infrastructure, lack of inputs, and diminishing herd sizes due to drought and diseases. The study concluded that cattle production remained a priority livelihood for the smallholder farmers with multiple roles including direct income and supporting other enterprises such as cropping. The smallholder participation in the BVC remains critical for the livestock development programmes. Recommendations were framed around capacity building efforts, innovations around extension methods, improving market access, herd rationalization and supporting modern farming practices such as breed improvement and feedlots.
Genetically tractable embryonic cell lines from sea urchins
Authors: Bodnar Andrea , Castellano Kate , Manner Carl , Kell Riss , McAtee Reanna , Capozzi Nicole , Wray Gregory 
Published: January 2025

Abstract

Sea urchins have been valuable research models for more than a century, significantly contributing to our knowledge of fundamental biological processes like cell cycle regulation and developmental gene regulatory networks. While an increasing number of functional genomic resources are being developed for sea urchins, in vitro cell culture tools and methods for scalable transgenesis have remained elusive. Here, we successfully established embryonic cell lines from sea urchins (Lytechinus variegatus and Strongylocentrotus purpuratus) which recapitulated aspects of the developmental program in vitro, generating 3D structures and a variety of morphologically and functionally distinct cell types representing all three germ layers. Single-cell transcriptional profiles revealed signatures of stem cells and distinct cell clusters expressing markers of neurons, myocytes, skeletogenic, endodermal, and pigment cells. The ability to genetically manipulate cultured cells was demonstrated using a lentiviral vector, providing a scalable approach for mechanistic studies that significantly expand the utility of this model organism.
Does the preliminary viewing of the embryo to be transferred on the monitor, followed by the ultrasound-guided transfer, lower the patient's stress? A descriptive and observational study
Authors: Baldini G. M , Lot D. , Malvasi A. , Laganà A. S. , Cerbone M. , Baldini D. , Trojano G. 
Published: January 2025

Abstract

The challenges associated with infertility and its treatments impose considerable psychological and physical burdens on patients, highlighting the critical need for patient-centred care to optimise therapeutic outcomes. This observational study assessed patient satisfaction with two specific aspects of in vitro fertilisation (IVF) treatment: ultrasound-guided embryo transfer and the opportunity to view embryos on a screen before transfer. Additionally, we explored the role of continuous care by the same physician in enhancing patients' sense of security and trust. The study was conducted at the IVF MOMO’ FertiLIFE center in Bisceglie, Italy, with 200 patients who completed a structured questionnaire assessing their experiences. Participants’ responses were evaluated using a 5-point Likert scale, specifically focusing on their emotional reactions to the transfer procedure, perceived levels of discomfort, sense of security, and preferences regarding continuity of care with the same physician. Statistical analyses included descriptive statistics, Spearman’s correlations, Friedman’s test, and factor analysis to explore relationships between variables and identify underlying factors. The findings revealed that ultrasound-guided transfer and embryo viewing significantly enhanced patients' emotional well-being, with many reporting increased feelings of calmness and security during the procedure. Continuity of care provided by the same physician was further associated with greater satisfaction and trust. These results underscore the psychological significance of patient-centred approaches, suggesting that integrating advanced technologies and promoting continuity in care could enhance the overall experience of IVF treatments, ultimately contributing to improved patient outcomes.
Social media addiction and its association with sleep quality and anxiety: A school-based cross-sectional study from Nepal.
Authors: Pradhan Laxmi , Adhikari Prakash , Shah Kriti , Bhusal Sandesh , Oli Kamana , Khanal Pratik , Singh Anil Kumar 
Published: January 2025

Abstract

Background
Excessive use of social media is linked with poor sleep quality and negative mental health outcomes. However, studies assessing the interplay of these three components among school children are exceedingly rare. This study aims to assess the levels of social media addiction, poor sleep quality, and anxiety among higher secondary school children, identify associated factors, and explore the correlations among these components.
Methods
This study was conducted among 418 higher secondary school students. Multivariable logistic regression at a significance level of 0.05 was employed to determine factors associated with social media addiction, poor sleep quality, and anxiety. Additionally, a correlation test was used to examine the associations between social media addiction, poor sleep quality, and anxiety.
Results
The prevalence rates of social media addiction, poor sleep quality, and anxiety were 33.5%, 64.4%, and 59.6%, respectively. Female students (aOR: 2.6; 95% CI: 1.6–4.1) and students from private schools (aOR: 3.7; 95% CI: 2.0-6.8) had greater odds of being addicted to social media. Students from the Brahmin/Chhetri ethnic group (aOR: 0.5; 95% CI: 0.3–0.9) had lower odds of experiencing poor sleep quality than the other groups did. Female students (aOR: 2.4; 95% CI: 1.6–3.6) were more likely to experience anxiety. Additionally, sleep quality and anxiety were weakly positively correlated with social media addiction.
Conclusion
Excessive social media use is associated with poor sleep quality and increased anxiety among Nepalese higher secondary students. Interventions such as face-to-face counseling, digital detox programs, and tailored approaches for high-risk groups are essential to address these issues and enhance their overall well-being.
Clinical trial number:
Not applicable
Methodology Development for Capturing Co2 and Precursor Gases of Greenhouse Effect From the Exhaust of Flex-fuel Internal Combustion Engines
Authors: Costa Theles 
Published: January 2025

Abstract

Derived largely from the combustion of fuels used in automotive vehicles, CO2 and precursor gases of greenhouse effect are important emission gases and deserve attention. This paper proposes a method to remove these gases by adsorption, through the capture and separation in exhaustion of vehicles with flex-fuel technology. The technique is feasible because it is based on the solid adsorption capacity and selectivity for CO2 and precursor gases. The characterization of the used adsorbents, natural ZN2040 and synthetic Oxan_X, show unique characteristics, especially the surface area, adsorption at low pressures, stability to wet gases, application at high temperature, high Si/Al ratio in the crystal structure and the presence of elements such as Fe, Ca, K and S. The adsorbents were arranged in a horizontal fixed bed column, installed in the front vehicle noise muffler of the exhaust system. The Oxan_X synthetic zeolite with improved performance, showed reductions in average of 2,20% of CO2 about 17% on the precursor gases, mainly CO, both for Gasoline 22% EAAF (Ethyl Alcohol Anhydrous Fuel) and ethanol burning. In addition, it allowed the reduction of other vehicle pollutants. In the long term, the use of vehicular fixed bed column contributes to a reduction of approximately 764000 tons of CO2 and 23300 t of CO when the vehicle is operating with Gasoline, and 1168000 tons of CO2 and 18000 t of CO when it is operating with Ethanol. Considering the vehicles of motorization 1.4 L to 2.0 L, and employing 2.0 kg of adsorbent.