bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cronkhite-Canada Syndrome Masquerading as Inflammatory Bowel Disease
Authors: Leong Justin Wen Hao , Wang Lai Mun , Li James Weiquan , Ang Tiing Leong , Kwek Boon Eu Andrew , Ong Jeannie Peng Lan 
Published: September 2023

ABSTRACT
Cronkhite-Canada syndrome (CCS) is a rare nonhereditary gastrointestinal polyposis syndrome. We illustrate a case with clinical presentation of dysgeusia, chronic diarrhea and weight loss, and endoscopic features of diffuse gastric mucosa nodularity with circumferential nodular pancolitis and a solitary colonic polyp initially mimicking inflammatory bowel disease. After multidisciplinary discussion, the diagnosis of CCS was made. The patient received steroids with resultant clinical, endoscopic, and histological improvement. We discuss the treatment and risk of neoplasia in CCS.
Lenvatinib-Induced Tumor Lysis Syndrome in Advanced Hepatocellular Carcinoma
Authors: Goyal Manjeet Kumar , Singh Arshdeep , Kumar Gupta Yogesh , Kaur Dhaliwal Kanwarpal , Sood Ajit 
Published: September 2023

ABSTRACT
This case report describes a 48-year-old man with hepatocellular carcinoma who developed tumor lysis syndrome (TLS) after 7 days of starting lenvatinib therapy. The patient was hospitalized and received appropriate interventions, including aggressive hydration, allopurinol, rasburicase, and electrolyte management. The patient's condition improved, and he was eventually discharged from the hospital. This case highlights the potential risk of TLS in patients with hepatocellular carcinoma receiving lenvatinib therapy, even after a short duration, and emphasizes the importance of early recognition and management of TLS to prevent serious complications.
Nutzer*innenzentriert und interaktiv: Methoden zur Evaluierung von FID-Portalen am Beispiel des FID Darstellende Kunst
Authors: Schlebbe Kirsten , Bressel Paulina , Greifeneder Elke , Voß Franziska 
Published: September 2023

Zusammenfassung
Der vorliegende Artikel beschäftigt sich mit der Frage, welche Methoden genutzt werden können, um eine Evaluierung von Services und Angeboten von Fachinformationsdiensten nutzer*innenzentriert und interaktiv umzusetzen. Als Beispiel dient der Fachinformationsdienst Darstellende Kunst, bereitgestellt von der Universitätsbibliothek Johann Christian Senckenberg in Frankfurt am Main. Drei unterschiedliche Methoden werden in diesem Zusammenhang näher vorgestellt und ihre Anwendbarkeit für die Evaluierung von FID-Portalen oder vergleichbaren Rechercheportalen reflektiert: Leitfaden-Interviews mit Think-Aloud-Elementen, virtuelle Fokusgruppen sowie ein digitaler Card-Sorting-Ansatz.
Panax ginseng leaf aqueous extract mediated green synthesis of AgNPs under ultrasound condition and investigation of its anti-lung adenocarcinoma effects
Authors: Ni Jingli , Negm Sally , El-kott Attalla F. , Ghamry Heba I. , Karmakar Bikash 
Published: September 2023

Abstract

Panax ginseng has many therapeutic uses in medicine. In the recent research, silver nanoparticles (AgNPs) were formulated by the Panax ginseng aqueous extract. The synthesized AgNPs’ characterization was analyzed using UV-Vis spectrophotometry, energy dispersive X-ray spectroscopy, scanning electron microscopy, fourier transformed infrared spectroscopy, transmission electron microscopy, and elemental mapping. The AgNPs were analyzed for their surface morphology by SEM. The successful synthesis of AgNPs was evident with TEM images. The AgNPs had a uniform distribution and homogenous spherical shaped morphology with mean diameter in the range of 20–30 nm. The cytotoxic and anti-lung adenocarcinoma ‎potentials of biologically formulated AgNPs‎ against NCI-H1563‎, NCI-H1437‎, NCI-H1299‎, and NCI-H2126 cells were determined. The anti-lung adenocarcinoma ‎ properties of the AgNPs ‎ removed NCI-H1563‎, NCI-H1437‎, NCI-H1299‎, and NCI-H2126 cells. The AgNPs’ IC50‎ were 193, 156, 250, and 278 µg/mL against NCI-H1563‎, NCI-H1437‎, NCI-H1299‎, and NCI-H2126 cells, respectively. Also, AgNPs presented high antioxidant potential.
Organic compounds as corrosion inhibitors for reinforced concrete: a review
Authors: Alvarez Leonardo X. , Troconis de Rincón Oladis , Escribano Jorge , Rincon Troconis Brendy C. 
Published: September 2023

Abstract
With the goal of preventing concrete deterioration by means of destructive corrosion processes, the use of single organic compounds or mixtures as organic corrosion inhibitors (OCIs) instead of inorganic chemicals is becoming a very attractive practice. As OCIs are more ecologically friendly in their production and environmental fate, they have several advantages over well-known inorganic additives such as metallic nitrites, chromates, or arsenates. In this article, the application of different single organic compounds (of either natural or synthetic origin) as well as mixtures that have been used to lengthen the lifespan of concrete structures is reviewed. After a small exemplification of the use of single organic compounds bearing amino, hydroxy, formyl, or carboxylic functionalities, the more often used OCIs are reviewed according to their principal functional group. Afterward, the application of compound mixtures of either synthetic or natural origin, the use of natural extracts, and biomass are surveyed. Finally, the effects of functional groups within the top 10 inhibitor molecules, the toxicity of OCIs, their effects on the physical-mechanical properties of concrete, and their long-term performance are discussed.
Discursive Fluctuations of the School Library Program in Chile: A Critical Policy Analysis
Authors: García-González Macarena , Velázquez-Burgos Rodrigo , Véliz Soledad , Oyarzún Juan de Dios , Saona Ignacia 
Published: September 2023

AbstractIn Latin America, school libraries were founded based on the hopes of fostering democracy and reducing social and educational inequalities. Nevertheless, current dominant discourses relate school libraries more closely to the demand to improve academic results. In this article, we explore what we consider to be an intensification of neoliberal discourses about school libraries by studying the case of the Learning Resource Centres (Centros de Recursos para el Aprendizaje,CRA) in Chile, a program that has been exemplary compared to other Latin American countries. With a Critical Policy Analysis (Bacchi 2009.Analysing Policy: What’s the Problem Represented to be?Australia: Pearson, 2012.Engaging with Carol Bacchi. Strategic Interventions and Exchanges. Adelaide: University of Adelaide Press, 2015. “The Turn to Problematization: Political Implications of Contrasting Interpretive and Poststructural Adaptations.”Open Journal of Political Science5 (1): 1–12), we question the problems that the CRA produce and aim to solve and their transformations through time. We focus on four public policy documents tracing how school libraries are related to the global educational reforms of the late 1980s and the 1990s and how they are assessed in the 2010s. We read the documents sketching out three exclusions that, we argue, lay the foundation for a neoliberal intensification of the CRA program: the exclusions of pedagogical innovation, of other learning resources beyond books, and of the local community.
Locus Coeruleus Integrity Is Linked to Response Inhibition Deficits in Parkinson's Disease and Progressive Supranuclear Palsy
Authors: Ye Rong , Hezemans Frank H. , O'Callaghan Claire , Tsvetanov Kamen A. , Rua Catarina , Jones P. Simon , Holland Negin , Malpetti Maura , Murley Alexander G. , Barker Roger A. , Williams-Gray Caroline H. , Robbins Trevor W. , Passamonti Luca , Rowe James B. 
Published: September 2023

Parkinson's disease (PD) and progressive supranuclear palsy (PSP) both impair response inhibition, exacerbating impulsivity. Inhibitory control deficits vary across individuals and are linked with worse prognosis, and lack improvement on dopaminergic therapy. Motor and cognitive control are associated with noradrenergic innervation of the cortex, arising from the locus coeruleus (LC) noradrenergic system. Here we test the hypothesis that structural variation of the LC explains response inhibition deficits in PSP and PD. Twenty-four people with idiopathic PD, 14 with PSP-Richardson's syndrome, and 24 age- and sex-matched controls undertook a stop-signal task and ultrahigh field 7T magnetization-transfer-weighted imaging of the LC. Parameters of “race models” of go- versus stop-decisions were estimated using hierarchical Bayesian methods to quantify the cognitive processes of response inhibition. We tested the multivariate relationship between LC integrity and model parameters using partial least squares. Both disorders impaired response inhibition at the group level. PSP caused a distinct pattern of abnormalities in inhibitory control with a paradoxically reduced threshold for go responses, but longer nondecision times, and more lapses of attention. The variation in response inhibition correlated with the variability of LC integrity across participants in both clinical groups. Structural imaging of the LC, coupled with behavioral modeling in parkinsonian disorders, confirms that LC integrity is associated with response inhibition and LC degeneration contributes to neurobehavioral changes. The noradrenergic system is therefore a promising target to treat impulsivity in these conditions. The optimization of noradrenergic treatment is likely to benefit from stratification according to LC integrity.SIGNIFICANCE STATEMENTResponse inhibition deficits contribute to clinical symptoms and poor outcomes in people with Parkinson's disease and progressive supranuclear palsy. We used cognitive modeling of performance of a response inhibition task to identify disease-specific mechanisms of abnormal inhibitory control. Response inhibition in both patient groups was associated with the integrity of the noradrenergic locus coeruleus, which we measuredin vivousing ultra-high field MRI. We propose that the imaging biomarker of locus coeruleus integrity provides a trans-diagnostic tool to explain individual differences in response inhibition ability beyond the classic nosological borders and diagnostic criteria. Our data suggest a potential new stratified treatment approach for Parkinson's disease and progressive supranuclear palsy.
Effectiveness of a web-based self-help tool to reduce problem gambling: A randomized controlled trial
Authors: Boumparis Nikolaos , Baumgartner Christian , Malischnig Doris , Wenger Andreas , Achab Sophia , Khazaal Yasser , Keough Matthew T. , Hodgins David C. , Bilevicius Elena , Single Alanna , Haug Severin , Schaub Michael P 
Published: September 2023

AbstractBackground and AimsProblem gambling constitutes a public health concern associated with psychopathological comorbidity, substance use, and financial difficulties. Most individuals with gambling problems avoid counseling services due to perceived stigma and their preference for self-reliance. Treatment accessibility could be improved through web-based interventions.MethodsWe recruited 360 individuals with gambling problems and randomized them to a web-based intervention (n = 185) or an active control group consisting of a self-help manual for problem gambling (n = 175). The primary outcome was the number of days of gambling in the last 30 days. Secondary outcomes included money spent in the last 30 days, time gambling in the last 7 days, gambling-related problems, consumption of alcohol and cigarettes, and psychopathological comorbidity measured at posttreatment and 6-month follow-up.ResultsThe primary outcome decreased significantly for both groups, with no significant difference between the groups. There were significant group × time interactions according to the Gambling Symptom Assessment Scale (F = 8.83, p <0 .001), the Problem Gambling Severity Index (F = 3.54, p = 0.030), for cigarettes smoked in the last 7 days (F = 26.68, p < 0.001), the Patient Health Questionnaire-9 (F = 19.41, p <0 .001), and the Generalized Anxiety Disorder-7 (F = 41.09, p <0 .001) favoring the intervention group. We experienced an overall high dropout rate (76%).ConclusionsWin Back Control seems to be an effective low-threshold treatment option for individuals with gambling problems that might otherwise be unapproachable for outpatient treatment services. Nevertheless, the high dropout rate should be considered when interpreting the study results, as they may have introduced a degree of variability.
Injusticia ambiental y violaciones de los derechos humanos en Jalisco, México
Authors: Venegas-Sahagún Beatriz Adriana , Gran-Castro Juan Alberto 
Published: September 2023

La injusticia ambiental trastoca los derechos humanos de las poblaciones. Este artículo se centra en el estado de Jalisco, México, territorio en el que se registraron el 70 % de las violaciones a los derechos humanos en materia ambiental entre 2016 y 2019. El objetivo es analizar las recomendaciones emitidas por la Comisión Estatal de Derechos Humanos de Jalisco en términos de violación de los derechos a un medioambiente sano, desde el 2000 al 2022. Para ello, se realizó un análisis cualitativo a través de datos hemerográficos de esta institución, los cuales se sistematizaron en categorías analíticas según el tipo de injusticia ambiental. Aunado a esto, se presentaron tres casos emblemáticos de violación a los derechos humanos en la materia. Los hallazgos muestran que las recomendaciones se vinculan con situaciones de contaminación de los cuerpos de agua y con la falta de suministro y su privatización; con la pérdida de la biodiversidad o con afectaciones a esta; y con el mal manejo de los residuos sólidos urbanos. Estos problemas se dan particularmente a través de procesos de distribución desigual de los impactos ambientales y de la exclusión de las personas afectadas en la toma de decisiones. Los resultados evidencian el lento proceso de reconocimiento a nivel institucional para señalar la transgresión al derecho a tener un ambiente sano en Jalisco.
Occupational therapists' acceptance of 3D printing
Authors: Barter Shelley Louise , Williams Alexandra Jean , Rencken Gina , Ndaba Nonjabulo , Govender Pragashnie 
Published: September 2023

INTRODUCTION: In occupational therapy, three-dimensional printing is being explored as an alternative design and manufacturing technique to the conventional fabrication of orthotics and assistive devices. The global applications and literature are rapidly growing, but the South African - specific literature is deficient. The Technology Acceptance Model depicts that one's perception of any particular technology is a significant determinant of their acceptance of it, determining whether the technology system is successfully adopted or disregarded AIM: To determine the perceived acceptance of three-dimensional printing technology amongst occupational therapists in KwaZulu-Natal and whether exposure to the technology system, in the form of a three-dimensional printing workshop, influences their perception of the technology METHOD: The study followed a multi-method design consisting of two phases; phase one involved the creation of the intervention tool (workshop), which was developed through a process guided by Design-Based Research. Phase two involved the implementation of the intervention and data collection. Therapists documented their perceptions in a questionnaire before and after exposure; following a pre and post-test design, enabling comparison. The questionnaires were based on the Technology Acceptance Model, including 13 questions scored on a seven-point Likert scale and five open-ended questions. The quantitative data were analysed descriptively, and qualitative data were analysed thematically RESULTS: All four categories of the Technology Acceptance Model-based questionnaire displayed a significant change (p < 0.05) between the pre and post-test responses, with a medium effect size CONCLUSION: Exposure to three-dimensional printing influences therapists' perception of the technology IMPLICATIONS FOR PRACTICE • The application of Three-Dimensional Printing (3DP) in occupational therapy practice has the potential to enable increased accuracy and precision of items fabricated by therapists; enabling customisation and individualisation to the exact specifications of a patient. • 3DP can open doors to a broad spectrum of items that are not easily accessible, affordable, or not even available, accessing ideas and blueprints from a global pool of resources through open-source sites. • With the process of fabrication being digital, not only does this reduce manual labour, but fabricating without touching the patient can reduce pain and prevent disruption of a repair/ surgical site/ wound. • The digital process also allows patients to see and visualise the product during the design process, enabling input prior to printing, contributing to reduced wastage.
Lógica digital y tecnología de computadores. Un enfoque práctico mediante simulación con Logisim
Authors:   Universidad de Castilla-La Mancha, Salido Terceroi Jesús 
Published: September 2023

Esta obra está concebida como manual docente para la asignatura de primer curso Tecnología de Computadores impartida en el grado en Ingeniería Informática de la Universidad de Castilla-La Mancha, aunque puede ser empleado en otras titulaciones para materias relacionadas con el Diseño y Análisis de Sistemas Digitales. El texto se divide en tres partes:	I.- Representación de información y lógica booleana (Caps. 1 a 3),	II.- Sistemas Combinacionales (Caps. 4 a 6), y	III.- Sistemas Secuenciales (Caps. 7 a 9). El rasgo diferenciador de esta obra reside en su enfoque práctico mediante utilización intensiva de simulación lógica de circuitos digitales. De este modo se facilita la experimentación inmediata e intuitiva de los circuitos digitales, independientemente de su complejidad. En una primera aproximación, la simulación lógica de los circuitos permite obviar los aspectos prácticos de su realización física, otorgando más relevancia a los aspectos formales de su análisis y diseño lógico. La herramienta de simulación opensource elegida en esta obra ha sido Logisim [1] (www.cburch.com/logisim), un programa multiplataforma de software libre. En los nueve capítulos de esta obra se incluyen 122 ejemplos prácticos explicados que cubren tanto el análisis como diseño de sistemas lógicos, y alrededor de 170 circuitos lógicos elaborados con Logisim, que se pueden recrear fácilmente. Cada capítulo finaliza con una sección de problemas propuestos, hasta un total de 174, cuya resolución se aborda en una obra complementaria.
Hubungan Keragaman Pangan Individu dan Status Gizi Anak 2-5 Tahun di Desa Batur Kecamatan Getasan Kabupaten Semarang
Authors: Prasetyo Age , Davidson Sarah Melati , Sanubari Theresia Pratiwi Elingsetyo 
Published: September 2023

Latar Belakang: Dalam konteks pedesaan, permasalahan ketahanan pangan cenderung masih menjadi tantangan. Keadaan tersebut muncul karena kurangnya keragaman diet dan berakibat pada gizi keluarga, terutama pada anak balita.
Tujuan: Penelitian ini dilakukan untuk mengetahui hubungan keragaman pangan individu dan status gizi anak 2-5 tahun di Desa Batur, Kabupaten Semarang.
Metode: Penelitian ini merupakan penelitian observasional dengan desain cross-sectional. Responden adalah keluarga yang memiliki balita usia 2-5 tahun yang tergabung di Posyandu Desa Batur wilayah kerja Puskesmas Getasan. Instrumen penelitian ini menggunakan kuesioner food recall 1x24 jam dan diolah berdasarkan Individual Dietary Diversity Score (IDDS). Pengambilan sampel dilakukan dengan teknik simple random sampling dan sebanyak 95 balita yang sesuai kriteria. Status gizi dinilai berdasarkan indikator TB/U, BB/U, dan BB/TB. Data yang dikumpulkan selanjutnya diolah menggunakan uji spearman.
Hasil: Keragaman pangan signifikan berhubunagn dengan status gizi balita berdasarkan indikator TB/U (r=0,618; p<0,001), BB/U (r=0,545; p<0,001), dan BB/TB (r=0,325; p=0,001). Tingkat korelasi yang kuat ditunjukkan antara keragaman pangan IDDS dengan status gizi indikator TB/U dengan nilai (r=0,618).
Kesimpulan: Keragaman pangan merupakan faktor yang berhubungan dengan terjadinya masalah gizi pada balita di Desa Batur.
Hubungan Tingkat Konsumsi Makan dan Aktivitas Fisik dengan Status Gizi Anggota Ekstrakurikuler Paskibraka
Authors: Hidayanti Fitria , Soeyono Rahayu Dewi 
Published: September 2023

Latar Belakang: Indonesia memiliki pasukan pengibar bendera pada kegiatan upacara kemerdekaan yang dikenal sebagai Paskibraka. Status gizi baik merupakan salah satu syarat yang harus dipenuhi untuk menjadi Paskibraka. Tingkat konsumsi makan dan aktivitas fisik menjadi faktor yang berpengaruh terhadap status gizi.
Tujuan: Kajian ini bertujuan untuk melihat korelasi tingkat konsumsi makan dan aktivitas fisik terhadap status gizi anggota ekstrakurikuler Paskibraka SMAN 1 Bangkalan, Indonesia.
Metode: Penelitian ini merupakan jenis penelitian kuantitatif korelasional menggunakan pendekatan cross-sectional. Metode total sampling mengambil sampel sebanyak 56 siswa ekstrakurikuler Paskibraka, berusia 15-16 tahun. Variabel bebas penelitian meliputi tingkat konsumsi makan dan aktivitas fisik, variabel terikatnya yaitu status gizi. Instrumen yang digunakan yaitu kuesioner identitas responden, kuesioner SQ-FFQ (Semi Quantitative Food Frequency Questionnaire) dan kuesioner GPAQ (Global Physical Activity Questionnaire. Data dianalisis menggunakan korelasi Rank Spearman.
Hasil: Tingkat konsumsi makan siswa normal (energi=76,8%, protein=58,9%, lemak=73,21%, karbohidrat=69,64%) dengan 75% sampel memiliki aktivitas fisik sedang dan 89,29% sampel memiliki status gizi baik. Tingkat konsumsi makan (energi p=0.011, lemak p=0.024 dan karbohidrat p=0.003) memiliki korelasi terhadap status gizi, tetapi tingkat konsumsi protein (p=0.141) dan aktivitas fisik (p=0.626) tidak memiliki korelasi terhadap status gizi siswa.
Kesimpulan: Tingkat konsumsi makan (energi, lemak dan karbohidrat) memiliki korelasi terhadap status gizi, tetapi tingkat konsumsi protein dan aktivitas fisik tidak. Penting bagi seorang siswa ekstrakurikuler Paskibraka untuk selalu memperhatikan tingkat konsumsi makan dan aktivitas fisik disetiap harinya agar memiliki status gizi yang baik.
Apakah Asupan Natrium Berlebih Merupakan Faktor Risiko Overweight?: Tinjauan Sistematis
Authors: Furqonia Annisaa Wulida , Farapti Farapti , Notobroto Hari Basuki 
Published: September 2023

Latar Belakang: Konsumsi garam dunia melebihi hingga 200% dari rekomendasi harian. Obesitas merupakan masalah kesehatan terbesar ketiga didunia. Berbagai penelitian mulai menggali mekanisme potensial hubungan antara asupan natrium dengan peningkatan berat badan, risiko kelebihan berat badan dan obesitas.
Tujuan: Menganalisis hubungan antara asupan natrium dengan risiko kelebihan berat badan ditinjau dari status gizi, obesitas sentral dan komposisi tubuh pada populasi dewasa.
Metode : Penelitian ini merupakan tinjauan sistematis. Proses pengumpulan data menggunakan database Pubmed dan Science Direct dengan kata kunci “obese” OR “overweight” OR “adiposity” AND “sodium” OR “salt intake” AND “adult”. Artikel dipilih melalui seleksi judul dan abstrak yang kemudian diseleksi kembali sesuai dengan kriteria inklusi dan eksklusi.
Ulasan: Terdapat 11 literatur terkait status gizi, 10 literatur terkait obesitas sentral, 3 literatur terkait komposisi tubuh. Asupan natrium berhubungan dengan peningkatan berat badan dan risiko kelebihan berat badan peningkatan berat badan hingga 2,75 kg, peningkatan lingkar pinggang hingga 2,15 cm dan peningkatan massa lemak hingga 0,91 kg. Mekanisme potensial yang mendasari hubungan ini antara lain dimediasi dengan asupan energi, peningkatan volume ekstraseluler, peningkatan adipositas, dan perubahan leptin plasma.
Kesimpulan: Terdapat hubungan konsumsi garam berlebih dengan peningkatan berat badan dan faktor risiko kelebihan berat badan dilihat dari status gizi, obesitas sentral dan komposisi tubuh pada populasi orang dewasa. Namun, mekanisme terjadinya hubungan tersebut masih perlu dipelajari lebih lanjut.