bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of polymyxin B with different administration methods in the critically ill patients with ventilation associated pneumonia: a single-center experience
Authors: Shi Rupeng , Fu Yuanyuan , Gan Yujing , Wu Danying , Zhou Suming , Huang Min 
Published: September 2023

Background: Whether nebulized polymyxin B should be used as an adjunctive therapy or substitution strategy to intravenous polymyxin B for the treatment of ventilator-associated pneumonia (VAP) remains controversial. This study’s aim is to evaluate the efficacy and safety of different administration ways of polymyxin B in the treatment of ventilator-associated pneumonia caused by extensively drug-resistant Gram-negative bacteria(XDR-GNB).Methods: This retrospective cohort study enrolled ventilator-associated pneumonia patients caused by XDR-GNB treated with polymyxin B in the intensive care unit. Patients were categorized by the administration methods as intravenous (IV) group, inhaled (IH) group, and the intravenous combined with inhaled (IV + IH) group. Microbiological outcome and clinical outcome were compared in each group. The side effects were also explored.Results: A total of 111 patients were enrolled and there was no difference in demographic and clinical characteristics among the three groups. In terms of efficacy, clinical cure or improvement was achieved in 21 patients (55.3%) in the intravenous group, 19 patients (50%) in the IH group, and 20 patients (57.1%) in IV + IH group (p = 0.815). All three groups showed high success rates in microbiological eradication, as 29 patients with negative cultures after medication in inhaled group. Among all the patients who had negative bacterial cultures after polymyxin B, the inhaled group had significantly shorter clearance time than the intravenous group (p = 0.002), but with no significant difference in 28-day mortality. Compared with intravenous group, a trend towards a lower risk of acute kidney injury was observed in inhaled group (p = 0.025).Conclusion: From the perspective of minimal systemic renal toxicity, nebulized polymyxin B as a substitution strategy to intravenous polymyxin B for the treatment of ventilator-associated pneumonia caused by XDR-GNB is feasible.
Comparative assessment of the SjSAP4-incorporated gold immunochromatographic assay for the diagnosis of human schistosomiasis japonica
Authors: Mu Yi , Rivera Jonas , McManus Donald P. , Weerakoon Kosala G. , Ross Allen G. , Olveda Remigio M. , Gordon Catherine A. , You Hong , Jones Malcolm K. , Cai Pengfei 
Published: September 2023

BackgroundSchistosomiasis, a disease caused by parasites of the genus Schistosoma, remains a global public health threat. This study aimed to validate the diagnostic performance of a recently developed gold immunochromatographic assay (GICA) for the detection of S. japonicum infection in a rural endemic area of the Philippines.MethodsHuman clinical samples were collected from 412 subjects living in Laoang and Palapag municipalities, Northern Samar, the Philippines. The presence of Schistosoma-specific antibodies in serum samples was tested with the SjSAP4-incorporated GICA strips and the results were converted to fully quantitative data by introducing an R value. The performance of the established GICA was further compared with other diagnostic tools, including the Kato-Katz (KK) technique, point-of-care circulating cathodic antigen (POC-CCA), droplet digital (dd) PCR, and enzyme-linked immunosorbent assays (ELISAs).ResultsThe developed GICA strip was able to detect KK positive individuals with a sensitivity of 83.3% and absolute specificity. When calibrated with the highly sensitive faecal ddPCR assay, the immunochromatographic assay displayed an accuracy of 60.7%. Globally, the GICA assay showed a high concordance with the SjSAP4-ELISA assay. The schistosomiasis positivity rate determined by the GICA test was similar to those obtained with the SjSAP4-ELISA assay and the ddPCR assay performed on serum samples (SR_ddPCR), and was 2.3 times higher than obtained with the KK method.ConclusionThe study further confirms that the developed GICA is a valuable diagnostic tool for detecting light S. japonicum infections and implies that this point-of-care assay is a viable solution for surveying endemic areas of low-intensity schistosomiasis and identifying high-priority endemic areas for targeted interventions.
Expanding the reach of vaccinology training in Africa: leveraging the success of the Annual African Vaccinology Course
Authors: Manga Nayna , Amponsah-Dacosta Edina , Hussey Gregory , Muloiwa Rudzani , Kagina Benjamin M. 
Published: September 2023

IntroductionIt is estimated that one in five African children lack access to recommended life-saving vaccines. This situation has been exacerbated by the COVID-19 pandemic which disrupted routine immunization services in several parts of the region. To better support recovery efforts and get immunization programmes back on track, policy makers, programme managers, immunization providers and academics need continuous upskilling. Unfortunately, the vaccinology training needed by these cadres remains limited and oftentimes inaccessible within our context. In addition, cadres should be continuously updated on advances in vaccinology so as to keep abreast with this rapidly evolving field. This calls for new and accessible approaches to training vaccinologists in Africa where the demand is high.MethodsThe aim of this proof-of-concept study was to ascertain the training needs of alumni of the Annual African Vaccinology Course and assess the effectiveness of an online webinar series in meeting those needs.ResultsWe found that alumni from across Africa required refresher training to gain up-to-date information about new developments in vaccinology, leverage opportunities to reinforce and consolidate their knowledge, and exchange country-specific experiences with their counterparts. A prominent motivation for refresher training was the rapid developments and challenges brought on by the COVID-19 pandemic. Drawing on the expressed needs of our alumni, we developed a webinar training series. This series aimed to provide participants with training on current and emerging trends in vaccinology with a focus on the regional context. Online participation in the webinar series was found to be comparable to previous in-person training, reaching a diverse group of cadres, and allowing for participation of a richer global faculty due to fewer cost constraints. Further to this, a post-training survey indicated that generally, alumni training needs were successfully met.DiscussionThe findings suggest that an online approach can be used to expand the reach of vaccinology training in Africa.
Makna Simbol Pada Koreografi Tari Kedokdok Kabupaten Ciamis
Authors: Putri Anisa Cahya Kemala , Nugraheni Trianti , Munsan Sri Dinar 
Published: September 2023

Artikel ini bertujuan untuk mendeskripsikan makna simbol yang terdapat pada koreografi Tari Kedokdok. Tari Kedokdok merupakan tarian yang berasal dari Kabupaten Ciamis. Masalah difokuskan kepada simbol dan makna yang terdapat di koreografi Tari Kedokdok. Pengumpulan data dilakukan melalui observasi, wawancara dan dokumentasi dengan menggunakan metode analisis deskriptif dan dianalisis secara kualitatif. Untuk mendekati masalah ini, referensi teori dari teori koreografi dan etnokoreologi digunakan. Dari penelitian ini diperoleh hasil bahwa bentuk tari Kedokdok dapat dilihat dari simbol dan makna yang terkandung dalam struktur koreografinya. Gerak dan penataan pada tarian ini tentunya mempunyai makna yang terselubung didalamnya. Gerak pada Tari Kedokdok mempunyai beberapa gerak tari yaitu gerak lampah ,amitan, ngawur, nilampah, natah, nyobaan kedhok, mulas, ngalage, siap karnaval , make kedhok, ngalaga, ngeyed, sodok kedhok, gibrig, ulin, ulin muiran, dan buka kedhok. Di dalam koreografi tarian tersebut terdapat 17 ragam gerak dengan 1 gerak Pure Movement, 9 gerak Locomotion dan 7 gerak Gesture. Penelitian ini penting untuk dilakukan karena dapat bermanfaat untuk menambah rujukan referensi bagi peneliti lain.
Extraction and Optical Study of Natural Dyes for Dye-Sensitized Solar Cell Application
Authors: Musyarofah Musyarofah , Prayitno Budi , Fauziyah Nur Aini , Nuraini Umi , Puspitasari Nurrisma 
Published: September 2023

Extraction and study of the optical properties of natural dyes from several plant parts such as leaves, flowers, tubers, and fruits have been carried out using a simple maceration method and UV-Vis absorption characterization. The samples were divided into several groups in this study, namely the flower group (Tagetes sp., Paeonia sp., Centaure sp., Chrysanthemum sp., Carthamus tinctorius, Gomphrena globosa, Myosotis sylvatica, Lavandula sp., Clitoria ternatea, Matricaria chamomilla, Hibiscus sabdariffa, and Rosa sp.); the leaf group (Mangifera indica, Moringa oleifera, Graptophyllum pictum, Spinacia oleracea, Citrus hystrix, and Terminalia sp.); and the tuber and fruit group (Solanum lycopersicum, Cucurbita moschata, Garcinia mangostana, Curcuma longa, Beta vulgaris, and Caessapina sp.). The extract of natural dyes was successfully produced using a low-cost and simple extraction approach via dehydration, immersion for 2×24 hours in ethanol, and followed by filtration. The optical properties of the dyes in UV and visible light range were observed using a UV-Vis spectrophotometer in the wavelength of 400-700 nm. The absorption behaviour showed dominant peaks at different wavelengths for each group. Potentially, to do a combination of dyes (co-sensitization: using more than a dye with different absorption spectra to achieve a panchromatic response) to widen the wavelength absorption for dye-sensitized solar cell (DSSC) applications.
Studi Pengaruh Temperatur Kalsinasi dalam Pembentukan Nanomagnetite dengan Metode Green Synthesis Ekstrak Daun Nanas
Authors: Putra Parmita Ade Wahyu Yusariarta , Panji  , Dewanto Hizkia Alpha , Sasongko Ashadi , Qulub Fitriyatul , Triana Yunita , Parmita Ade Wahyu Yusariarta Putra 
Published: September 2023

Pada proses sintesis nanopartikel Fe₃O₄ menggunakan metode green synthesis dengan menambahkan FeCl₃.6H₂O dan ekstrak daun nanas. Ekstrak daun nanas digunakan sebagai reduktor alami dimana memiliki kandungan hidroksil dan karbonil, yang bertindak sebagai agen pereduksi FeCl₃.6H₂O yang disintesis. Kemudian setelah presipitat didapatkan maka selanjutnya akan dilakukan kalsinasi. Dimana temperatur kalsinasi dalam sintesis menjadi faktor dalam pembentukan nanopartikel Fe₃O₄. Temperatur kalsinasi yang berbeda yaitu 400℃, 450℃ dan 500℃ diberikan untuk preparasi nanopartikel Fe₃O₄, dengan hasil uji XRD terkonfirmasi bahwa nanopartikel Fe₃O₄ terbentuk. Pada pengujian SEM-EDX variasi yang optimum adalah 400℃ karena rata-rata ukuran partikelnya 150,23 nm dengan bentuk partikel tidak beraturan. Kemudian dilanjutkan hasil SAA dengan luas permukaan 60,125 m²/g. Hasil UV-Vis didapatkan 52,79% pada material kalsinasi 450℃. Hasil dari visual test adsorpsi methylene blue dimana data pada nanopartikel kalsinasi 400℃ dan 450℃ mengalami degradasi dengan waktu hampir bersamaan
ANALISIS TREN PENYEBAB KEMATIAN MATERNAL DI KOTA TANGERANG BERDASARKAN HASIL AUDIT MATERNAL PERINATAL TAHUN 2016 – 2021
Authors: Rusmawati Sisca , Siregar Kemal Nazaruddin 
Published: September 2023

Hasil Long Form Sensus Penduduk 2020 menunjukkan Angka Kematian Ibu (AKI) di Indonesia masih cukup tinggi, sebesar 189/100.000 kelahiran hidup. Meskipun relative lebih baik dari beberapa kabupaten/kota di Provinsi Banten akan tetapi Kota Tangerang belum mampu menurunkan tingkat kematian ke angka zero death. Kebaruan penelitian ini karena meneliti tren penyebab kematian maternal berdasarkan hasil audit maternal perinatal. Tujuan penelitian untuk menganalissi tren dan penyebab kematian maternal di Kota Tangerang tahun 2016-2021. Penelitian ini merupakan penelitian deskriptif, pendekatan studi dokumentasi Audit Maternal Perinatal (AMP) di Kota Tangerang tahun 2016-2021 sebanyak 49 kasus. Kematian ibu di Kota Tangerang tahun 2016-2021 sebanyak 49, penyebab kematian terbanyak karena preeklampsia (51,1%), berdasarkan karakteristik ibu kematian pada rentang usia 20−35 tahun (65,3%); paritas 2−4 (49,0%), jarak kelahiran 2 tahun (89,8%); tanpa penyakit penyerta (79,6%), kunjungan ANC ≥ 4 kali (81,6%); pendidikan SMA (69,4%); periode kematian masa nifas (69,4%) dan tempat kematian di rumah sakit (93,9%); berdasarkan proses rujukan, jarak tempuh ke fasilitas kesehatan ≤ 5 km (98,0%); ketersediaan transportasi (100%); memiliki jaminan kesehatan (73,5%), memanfaatkan sistem komunikasi rujukan (57,1%); (89,8%) kematian maternal seharusnya dapat dicegah, berdasarkan faktor penyebab yang dapat dicegah (68,5%) dari faktor penyedia layanan, berdasarkan rekomendasi AMP 39,1% terbanyak untuk fasilitas kesehatan, berdasarkan kemampuan dalam melakukan tindak lanjut atas rekomendasi AMP Kota Tangerang dikategorikan “menengah” karena tindak lanjut atas rekomendasi sebanyak (59,4%). Kesimpulan bahwa tren kematian maternal di Kota Tangerang tahun 2016-2021 cenderung stagnan, penyebab terbesar kasus kematian maternal karena preeklampsia dan perdarahan.
HUBUNGAN PENGETAHUAN DAN SIKAP PELAJAR DENGAN TINDAKAN PENCEGAHAN DBD PADA SISWA SMA KRISTEN
Authors: Toru Veronika , Radandima Ester , Pekabanda Kartini , Mila Anthonetha R.H , Hara Maria Kareri 
Published: September 2023

Data dari Kementerian Kesehatan Demam Berdarah Dengue (DBD) di Indonesia mencapai 13.683 orang, di NTT yang menderita DBD sebanyak 1.337. Angka tersebut terus meningkat menjadi 1.563 orang. Kebaruan dalam penelitian ini karena menganalisis hubungan pengetahuan dan sikap pelajar dengan tindakan pencegahan DBD pada siswa SMA Kristen. Tujuan penelitian menganalisis hubungan pengetahuan dan sikap pelajar dengan tindakan pencegahan DBD pada siswa SMA Kristen. Metode penelitian kuantitatif dengan rancangan analitik observasional. Teknik Analisa data analisis univariat, bivariat, dan multivariat. Uji dua variabel menggunakan chi-square untuk mengetahui hubungan di antara variabel. Uji banyak variabel menggunakan regresi logistik biner mendapatkan nilai rasio odds (OR), 95% CI, dan nilai p, di mana setiap variabel dengan nilai p 0,25 diikutsertakan dalam uji banyak variabel menggunakan metode ENTER. Hasil analisis univariat menunjukkan sebagian besar mempunyai pengetahuan yang kurang baik yaitu 70%, sikap yang kurang baik yaitu 60%. Analisis bivariat menunjukkan adanya hubungan signifikan (P-value 0,001) antara pengetahuan, sikap dengan tindakan pencegahan DBD pada siswa SMA. Analisis multivariat menunjukkan variabel pengetahuan dan sikap secara statistik berhubungan dengan tindakan pencegahan DBD. Secara berturut-turut variabel yang paling berpengaruh adalah pengetahuan terdiri dari pendidikan yang baik berhubungan 6 kali dengan tindakan yang baik dalam pencegahan DBD (PR: 6,008;95%CI: 2,127-16,967; P-value 0,001), variabel sikap yaitu baik berhubungan 5 kali dengan tindakan yang baik dalam pencegahan DBD (PR: 4,682; 95%CI: 1,784-12,286; P-value 0,002). Kesimpulan terdapat korelasi antara pengetahuan, sikap, dan perilaku dalam mencegah penyakit DBD pada siswa SMA Kristen.
DETERMINAN KEJADIAN KISTA OVARIUM PADA WANITA USIA SUBUR DI RSIA SITTI KHADIDJAH GORONTALO
Authors: Kau Mayangsari , Adam Deysi , Djafar Lisa , Borolla Hendrik , Dengo Moh. Rivandi 
Published: September 2023

Menurut data statistik World Health Organization (WHO) tahun 2020 menunjukkan bahwa hampir semua negara maju memiliki angka kejadian kista ovarium yang tinggi dengan rerata 10 per 100.000 penduduk, kecuali Jepang dengan rerata 6,5 per 100.000 penduduk, kista ovarium adalah tumor jinak yang sering ditemukan pada wanita di usia reproduktif. Kebaruan dalam penelitian ini karena menganalisis faktor-faktor risiko tentang kejadian kista ovarium pada wanita usia subur. Tujuan dalam penelitian ini untuk menganalisis faktor-faktor risiko tentang kejadian kista ovarium pada wanita usia subur di RSIA Sitti Khadijah Gorontalo. Penelitian yang digunakan desain case control dengan sampel sebanyak 144 sampel menggunakan perbandingan 1:2 sehingga jumlah sampel kasus 48 pasien dan kontrol 96 pasien dengan menggunakan matching umur. Teknik pengambilan sampel dalam penelitian ini diambil secara purposive sampling. Hasil penelitian, dismenorea merupakan faktor risiko terhadap kejadian kista ovarium nilai OR 1,923 dengan (nilai LL =0,927 dan nilai UL = 3,988), riwayat keluarga merupakan faktor risiko terhadap kejadian kista ovarium nilai OR 1,145 dengan (nilai LL = 0,557 dan nilai UL = 2,354), lama haid merupakan faktor protektif terhadap kejadian kista ovarium nilai OR 0,664 dengan (nilai LL = 0,591 dan nilai UL = 0,746) sedangkan menarche merupakan faktor protektif terhadap kejadian kista ovarium nilai OR 0,878 dengan (nilai LL = 0,433 dan nilai UL = 1,778). Kesimpulan bahwa dismenorea, riwayat keluarga merupakan faktor risiko terhadap kejadian kista ovarium sedangkan lama haid dan menarche merupakan faktor protektif terhadap kejadian kista ovarium.
ENGARUH WORKPLACE STRECHING EXERCISE (WSE) TERHADAP PENURUNAN KELUHAN MUSKULOSKELETAL DISORDER (MSDs) PADA BIDAN DALAM PERTOLONGAN PERSALINAN
Authors: Retnosari Ekadewi , Fatimah Siti , Miskiyah Miskiyah 
Published: September 2023

Musculoskeletal disorders (MSDs) merupakan masalah kesehatan dan dapat berdampak berbahaya pada produktivitas kerja dan kualitas hidup para bidan dalam menolong persalinan. Hal ini dapat disebabkan posisi kerja yang janggal, manual handling dan berdiri dalam waktu lama. Salah satu upaya yang dapat dilakukan adalah Workplace Streching Exercise (WSE) dengan melakukan peregangan dapat menguragi masalah MSDs. Penelitian ini bertujuan untuk mengetahui pengaruh WSE terhadap penurunan keluhan MSDs pada bidan. Temuan kebaruan penelitian ini penggunaan WSE untuk menurunkan keluah MSDs pada bidan. Desain yang digunakan adalah pre experiment pretest-posttest without control. Subjek penelitian ini adalah Bidan yang melakukan praktik sebagai bidan desa atau Praktik Mandiri Bidan (PMB) di wilayah Kerja Kecamatan Muara Enim yang mengalami keluhan MSDs. Subjek sebanyak 60 orang. Responden melakukan WSE dengan menggunakan checklist WSE. Pengukuran MsDs menggunakan Nordic Body Map Questionare (NBM). Analisis data menggunakan uji Wilcoxon. Hasil penelitian diperoleh rata-rata skor Nordic body map adalah 33,27 (7,20) yang menunjukan keluhan MsDs sebelum penelitian. Rata-rata skor Nordic body map adalah 2,87 (1,84) yang menunjukan keluhan MsDs setelah penelitian. didapatkan penurunan keluhan MSDs sebanyak -30,40 (7,02) setelah dilakukan intervensi WSE, hasil uji statistic menunjukkan bahwa P-value 0,000 yang berarti bahwa ada pengaruh WSE terhadap penurunan keluhan MSDs pada bidan dalam pertolongan persalinan. Disimpulkan WSE dapat berpengaruh dalam menurunkan keluhan MSDs pada bidan dalam pertolongan persalinan. WSE dapat menjadi solusi dalam mengatasi masalah MsDs pada bidan saat menolong persalinan.
Pengaruh Penerapan Pembelajaran Kooperatif Tipe Mind Mapping terhadap Hasil Belajar Siswa Kelas V pada Pembelajaran Tematik
Authors: Rianita Riandini 
Published: September 2023

This study aims to analyze the effect of the application of a mind mapping type cooperative learning model on students' cognitive learning outcomes n thematic learning of grade V of State Elementary School 84 Sngkawang. The method used was an experiment with a quas experimental design type of nonequivalent control group desgn. The population was all students from two classes totaling 45 students. The samples of this study were VA class students totaling 23 students and VB class students totaling 22 students. The data collection technique used was a measurement technque and the data collection tool used was a wrtten test n the form of multiple choice. Based on data analysis, the average final test of the experimental class was 68. 52 and the average fnal test of the control class was 61.59. The results of the hypothesis test using the polled variance-test obtained tcount of 3.05 while ttable (α = 5%; dk = 23 + 22 - 2 = 43) amounted to 1.681 whch means tcount > ttable, then Ha s accepted. This proves that there s a difference n the final test results of students n the experimental and control classes, n other words, t proves that there s an effect of the application of the mind mapping type cooperative learning model on students' cognitive learning outcomes n thematic learning. Based on the results of the calculation of effect size (d), the result d = 0.92 was obtained, which included high criteria. Thus t can be concluded that the application of the mind mapping type cooperative learning model has a huge influence on students' cognitive learning outcomes n thematic learning n grade V of State Elementary School 84 Sngkawang.
An Efficient Method to Estimate Admittance of Black-boxed Inverter-based Resources for Varying Operating Points
Authors: Zhou Weihua , Liu Bin , Mohammed Nabil , Bahrani Behrooz 
Published: September 2023

<p>Admittance frequency responses of inverter-based resources (IBRs) are typically measured in the electromagnetic transient simulation or lab environments when their internal structures and parameters are unknown. Nevertheless, such ad?mittance measurements must be performed repeatedly when the operating point changes, since various non-linear control loops make the IBRs’ admittance models operating-point dependent. To avoid the time-consuming and cumbersome measurements, this letter presents a simple and efficient admittance estimation method for black-boxed IBRs, where the admittance at any arbitrary operating point can be estimated using as few as seven measured admittance data points. Case studies demonstrate that the proposed approach is efficient on various types of IBRs, including both grid-following and grid-forming inverters. The estimation accuracy is satisfying even when non-negligible measurement errors exist. </p>
Exogenous application of biostimulators alleviates water deficient stress on Azadirachta indica plants
Authors: Abou Dahab T.A.M. , Ashour Hossam Ahmed , Saber M.M.H. 
Published: September 2023

Pot experiment was conducted to evaluate the effect of chitosan or brassinolide applications on morphology and physiology parameters of Azadirachta indica grown under water deficient stress. The plants received different irrigation intervals, and were sprayed monthly with either chitosan or barrasenolide each at concentrations of 50, 100 and 200 ppm, while the control plants were sprayed only with tap water. The results showed that water stress reduced all growth parameters, chemical constituents of pigments content, total carbohydrates, N, P and K %, total indoles, while proline and total phenols content were increased. Instead, the plants sprayed with the higher concentrations of chitosan or brassinolide resulted in significant increase in growth parameters, pigments content, total carbohydrates, proline content, N, P and K %, total indoles while reduced total phenols content. Based on the obtained results it can be concluded that, foliar application of chitosan or brassinolide at 200 ppm can alleviate the adverse effects of water deficient stress on the growth and physiology parameters of Azadirachta indica.