bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optical-spectroscopic analysis of colorimetric changes in meat during its storage
Authors: Shkabrou A. U. , Chernukha I. M. , Raznichenka V. D. , Lazovikava L. U. 
Published: July 2023

The colorimetric and spectral characteristics of meat and their changes during the period of storage were researched. It was shown that spectral methods of analysis can potentially be used to assess the properties of meat during its storage in order to define the degree of autolytic changes which occur in the meat along with its histological-structural and proteomic changes. The work studies the quality characteristics of meat on the base of an array of its parameters and a correlation between them. Considerable attention is paid to the determination of colorimetric and spectral characteristics of autolytic and other changes in meat during its storage. The possibility of using the method of optical spectrometry for assessing the quality of meat is considered. The data obtained by processing the absorption spectra of aqueous extracts from muscle tissue confirm the promising prospects of using this method in a comprehensive study of the raw meat materials properties. The work proves possibility of classifying raw meat according to the degree of its autolysis for further assessment of its colorimetric characteristics, the value of extinction coefficients and the relative area of peaks at the wavelength λ415, λ525, λ542, λ555, and λ582.
Solar distillation of human urine to recover non-potable water and metal phosphate mineral
Authors: Bucholtz Pippin , Steele McKenzie , Tripathi Vedika , Graham Cole , Crane Lucas , Boyer Treavor H. 
Published: July 2023

Abstract

Human urine is a readily available nutrient source that can complement commercial fertilizer production, which relies on finite mineral resources and global supply chains. This study evaluated the effectiveness of a simplified solar distillation process for urine to recover phosphorus (P) and nitrogen for agricultural use and water for non-potable purposes. Synthetic fresh, synthetic hydrolyzed, real fresh, and real hydrolyzed urine were exposed to direct sunlight for 6 h in a simple distillation apparatus, which produced distillation bottoms and distillate. Metal phosphate precipitation in the distillation bottoms was evaluated to recover P. The non-potable water was recovered as distillate. Hydrolyzed urine recovered more metal phosphate solid in the distillation bottoms and had a higher conductivity in the distillate than fresh urine. Hydrolyzed urine also achieved greater distillate volume recovery than fresh urine. Hydrolyzed urine had a greater presence of UV-absorbing organics in the distillate than fresh urine and therefore produced a lower-quality product water. There was no significant correlation between the daily high air temperature and the volume of distillate recovered. This study provides a comprehensive data set on simplified solar distillation of human urine considering the fate of nutrients and water for different types of urine.
Prebiotics Modulate Gut Microbiota-mediated T-cell Immunity to Enhance the
Inhibitory Effect of Sintilimab in Lewis Lung Adenocarcinoma Model Mice
Authors: Yan Qin , Su Shitong , Dai Gangyi , He Lang 
Published: July 2023

Background:
Sintilimab (Sin) helps the body to restore the anti-tumor response of T lymphocytes. However,
in clinical use, the treatment process is more complicated due to adverse effects and different dosing regimens. It is
not clear whether prebiotics (PREB) have a potentiating effect on Sin for lung adenocarcinoma, and this study intends
to investigate the inhibitory effect, safety and possible mechanism of Sin combined with PREB on lung adenocarcinoma
from animal experiments.

Methods:
Lewis lung adenocarcinoma cells were inoculated into the right axilla of mice subcutaneously to prepare the
Lewis lung cancer mouse model and treated in groups. The volume of transplanted tumors was measured, the histopathology
of the liver and kidney of mice was observed by H&E staining, the levels of ALT, AST, UREA, CREA,
WBC, RBC, and HGB in blood were analyzed biochemically; the ratio of T-cell subpopulations in blood, spleen, and
bone marrow was detected by flow cytometry, the expression of PD-L1 in tumor tissue was detected by immunofluorescence
staining, and 16S rRNA to analyze the diversity of fecal flora.

Results:
Sin inhibited tumor growth and regulated immune cell homeostasis in lung adenocarcinoma mice, but liver
and kidney histopathology showed different degrees of damage after Sin treatment, while the addition of PREB reduced
liver and kidney damage in lung adenocarcinoma mice and promoted Sin's regulation of immune cells. In addition,
the beneficial effects of Sin were associated with changes in intestinal flora diversity.

Conclusion:
The mechanism by which Sintilimab combined with prebiotics inhibits tumor volume and regulates immune
cell subpopulation balance in lung adenocarcinoma mice may be related to gut microbes.
Woman in niqab and contestation of piety show-off in the media
Authors: Akalili Awanis , Udasmoro Wening , Noviani Ratna 
Published: July 2023

HIjrah is not only limited on human relation with God, but also how hijrah discourse existence is delivered in the media as discourse battle arena. Niqab is a characteristic of a woman going through hijrah. By using multimodality of Gunther Kress and Theo van Leuween, this critical discourse digs deeper on phenomena of woman in niqab and contestation of piety show-off in the media. Based on analysis performed on four accounts of woman with niqab in Instagram, narration found that the most massive show-off action of piety are performed by niqabis, that is in the act of religious activities, such as reading Al-Qur'an, praying, suggestion on sadaqa and five-times prayer. Moreover, piety representation is also performed by using quotes in Arabian language and Arabian woman figure as illustration to legitimate the hijrah journey of a woman in niqab. Piety, not only it displays woman in covering clothes, but also intersection with popular culture. It’s existence is put together with the incidentally profane Korean wave love romance This phenomena shows a paradox where there is incorporation of religious sacredness with the often considered profane Korean wave.
Presencia de mastocitoma en el pabellón auricular en un canino
Authors: Olivares-Muñoz Angelica , Cervantes-Perez Paloma , Vanegas-Casallas David , Canales-Rubio Miguel , Bravo-Ramos Jose L , Espín-Iturbe Teresa 
Published: July 2023

Los mastocitos cutáneos y subcutáneos son neoplasias compuestas por mastocitos que forman parte de la piel en los caninos. Es un tumor muy común y el tratamiento va enfocado a la agresividad que pudiera presentar. Ocasionalmente se puede administrar un tratamiento local, sin embargo, este no debe considerarse en pacientes con metástasis. La estadificac ión del tumor es de gran importancia para dar un diagnóstico, tratamiento y pronóstico para aquellos pacientes afectados por esta patología. En este trabajo se presenta el caso clínico de un canino Pastor Alemán de 11 años con la presencia de una estructura ulcerada en el pabellón auricular derecho. Se realizó diagnóstico por citología e histopatológico de mastocitoma canino grado II y baja malignidad de acuerdo con la clasificación de Pakiel. Al paciente se le realizó una resección parcial del pabellón auricular con presencia de bordes limpios en los resultados del estudio histopatológico. El objetivo de este trabajo es reportar un caso clínico con la presencia de mastocitoma en el pabellón auricular en un perro doméstico.
Degradasi Moral Pendidikan Di Era Modernisasi Dan Globalisasi
Authors: Hairiyah Hairiyah , Hayani Aida , Susilowati Ika Tri 
Published: July 2023

<p class="abstrak">Globalisasi dan moderniasi membawa dampak pada penurunan moral. Globalisasi dan modernisasi erat kaitannya dengan perkembangan teknologi dan informasi, secara khusus internet memberi peluang dan mempermudah masyarakat dalam mengerjakan berbagai aktivitas. Akan tetapi di balik kelebihan internet, nyatanya ada dampak negatif dari internet itu sendiri, yang berakibatkan pada degradasi moral yang di sebabkan oleh hadirnya <em>game online, </em>video-video yang tidak mendidik, dan lain sebagainya. Hasil penelitian menunjukkan dalam menghadapi degradasi moral pendidikan adalah keluarga. Peranan keluarga dan masyarakat sangat berpengaruh terhadap keberhasilan suatu pendidikan. Karena baik dan burukanya anak akan dilihat dari lingkungan keluarga dan lingkungan masyarakatnya. Dampak dari kurangnya keteladanan dari keluarga dan masyarakat adalah terjadinya berbagai macam problem degradasi moral, antara lain: penyalahgunaan narkoba, terjadinya sex bebas, kecanduan terhadap <em>game online, </em>diantara problem di atas yang paling akut adalah pornografi yang mana akan berdampak pada rusaknya mental anak. Untuk mengawal moralitas anak, orang tua perlu memahami metode pendidikan Islam dengan baik dan benar. Orang tua yang memahami metode Abdullah Nashih Ulwan secara menyeluruh dan dengan pemahaman yang mendalam. Akan berdampak baik pada pendidikan karakter anak yang menjadi benteng dalam menghadapi degradasi moral yang terjadi di era globalisasi saat ini</p>
Perancangan Sistem Informasi Pembayaran Keuangan Sekolah Berbasis Web Di SMA Negeri 1 Sungai Rumbai
Authors: Oktavia Desi 
Published: July 2023

Manajemen keuangan sekolah di SMA Negeri 1 Sungai Rumbai memiliki permasalahan dalam perhitungan data, pembuatan laporan, serta saat proses administrasi pembayaran SPP dan komite secara tunai yang dilakukan dengan jumlah nominal yang berbeda dengan buku yang berbeda pula, lalu diketik ulang sehingga membutuhkan waktu yang lama. Berdasarkan permasalahan tersebut maka diracanglah sistem informasi Pembayaran Keuangan Sekolah Berbasis Web dengan menggunakan model Unified Modeling Language (UML) dengan metode System Development Life Cycle (SDLC) yang mana pada model ini memiliki beberapa tahapan yaitu Analysis, Design, Implementasi, Testing, Development dan Maintenance. Dari penelitian ini, pengujian Sistem informasi dilakukan dengan pengujian blackbox testing sebanyak 3 menu pengujian yang mendapat hasil yang valid dan pengujian beta sebanyak 78,12% presentase penilaian. sistem ini berjalan dengan baik dan dapat mempermudah pengelolaan pembayaran keuangan siswa.
Statins in combination with Ibrutinib bypasses resistance to Ibrutinib in mantle cell lymphoma
Authors: Al-Zebeeby Aoula , Abbas Ali 
Published: July 2023

Objective: In this study, we report that a novel combination therapy of different statins with Ibrutinib can overcome such resistance.
Methods: For this, we generated a cell line model, exhibiting resistance to Ibrutinib, by repeated exposure of mantle cell lymphoma cell line to Ibrutinib. Apoptosis was assessed by the extent of phosphatidylserine externalisation.
Results: Our results indicated that resistance to Ibrutinib could be overcome by targeting a key enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in the cholesterogenesis pathway.
Conclusion: Reusing different statins in combination with Ibrutinib could improve therapy and enhance sensitivity to Ibrutinib mediated apoptosis.
Effect of Adipose Derived Stromal Vascular Fraction on The Early Inflammatory Phase of Burn Wound Healing in Male Rat Model
Authors: Noori Laura , Fakiha Khloud , Aljahdali Anan 
Published: July 2023

Objectives: Severe burn treatment remains challenging. Research has investigated the efficacy of stem cells and stromal vascular fraction (SVF) in many types of injuries. SVF has advantages for its heterogenous population of cells and avoidance of culturing and ethical issues. SVF can be isolated either enzymatically or mechanically. Enzymatically isolated SVF reduced inflammation and enhanced neovascularization and re-epithelization in the treatment of burn injury. This study highlighted the efficacy of applying mechanically isolated SVF on the early inflammatory phase of deep partial-thickness burn by investigating toll-like receptor 4 (TLR4) signaling pathway.
Methods: 30 male Wistar rats with deep partial-thickness burns were assigned into: the control group, silver sulfadiazine (SSD) cream group, and mechanically isolated SVF group. Morphological, histopathological evaluation of inflammation, and immunohistochemical analysis for (TLR4, TNF-α, IL‐1β, and IL-6) were evaluated for the first eight days post-treatment.
Results: Morphologically, the SVF group significantly reduced edema and increased wound bed dryness on day one compared to the control group (P=0.0001) and to the SSD group (P=0.001). Histopathologically, the SVF group significantly reduced inflammation four days post-treatment compared with the control group (P=0.045). The SVF group significantly reduced TLR4 protein expression on days four and eight post-treatment compared with the control group (P= 0.001, P= 0.042, respectively). The TNF-α protein expression in the SVF group was significantly lower on days four and eight post-treatment compared with the control group (P= 0.046, P= 0.046, respectively) and with the SSD group (P= 0.008, P= 0.001, respectively). The IL‐1β expression was significantly reduced in the SVF group compared to the control group on day four post-treatment (P= 0.017). There were no significant differences in IL-6 expressions between all groups on both days.
Conclusion: The mechanical isolation of SVF has an early anti-inflammatory impact on deep partial-thickness burn injury. This effect could be through inhibiting TLR4, TNF-α, and IL‐1β pathways. This could partially explain the mechanism behind SVF efficacy in the healing process of burn injury.
Effectiveness of radial Extracorporeal Shock Wave Therapy in Reduces muscle spasms in Stroke Patients; A Systematic Review and Meta-Analysis
Authors: Hameedi Isam Ali , Shadmehr Azadeh , Alsaadawi Tahir 
Published: July 2023

Objectives: Effectiveness of radial extracorporeal shock wave therapy (rESWT) on pain, range of motion and muscle tone in patients with stroke injuries.
Methods: PubMed, EMBASE, Cochrane Library and VIP information were used to collect information for research conducted between the beginning of 2013 and the end of 2022. These studies were randomized controlled trials that used rESWT for muscle spasm in stroke patients with conventional treatments as controls. There are no specific restrictions on the duration of treatment, the type of reESWT, or the severity of symptoms. These studies must have assessed at least one of the following outcome mesurements: visual analog scale (VAS) for pain, Ashwerth measure for muscle tone or external rotation range of motion (ER ROM). RevMan 5.3 software was used to check the quality of included studies. For continuous variables, mean difference (MD) or standardized MD (SMD) with CI 95% were derived. For dichotomous data, event proportions and sample sizes were extracted.
Results: In the conducted investigations, it was found that 7 studies investigated the effectiveness of rESWT treatments after the intervention in comparison with conventional treatment in terms of reducing pain intensity. In total, all 7 studies showed that the rESWT intervention was effective in reducing pain intensity compared to conventional treatments (MD, –0.97 [95% CI, –2.13 to –0.42], P < .00001, I2 = 71%). Compared with traditional treatments, the effectiveness of rESWT plus routine treatments on muscle tone after intervention was assessed in terms of Ashwerth critrion in 4 trials (SMD, 1.13 [95% CI, 0.46-1.23], P < .00001, I2 = 59%). ER ROM was used to reflect the ROM, which was assessed in 4 RCTs. Because of the limited number of studies, ER ROM was measured immediately after treatment in all included studies. The pooled result of the included studies showed that the heterogeneity was high and unacceptable (MD, 10.31 [95% CI, 2.47–16.18], P < .003, I2 = 81%).
Conclusion: The results of this research indicated that rESWT treatment can be used as a safe and non-invasive method to quickly reduce spasticity and increase joint range of motion in stroke patients. But more research on the long-term effects of rESWT as well as the factors influencing its effectiveness to reduce spasticity and comparison with other new treatment protocols is suggested.
Physiological Effects of Calprotectin and B Cell Activating Factor in COVID-19 Patients
Authors: Balaky Hazhar M. , Mustafa Akam Jasim , Ismail Parween Abdulsamad , Yousif Araz Muhammad 
Published: July 2023

Objectives: This study set out to determine how Calprotectin and B cell activating factor contributes to early COVID-19 patient severity prediction.
Methods: The study included 25 healthy controls and 52 patients with SARS-COV2 infection who were clinically diagnosed with COVID-19 illness and were between the ages of 23 and 35. The serum levels of CALP and BAFF were measured using the ELISA method. To gauge CRP levels, an immunoturbidometric assay was performed.
Results: Variations in serum levels of CALP and BAFF were found to be statistically insignificant in the study (P=0.7109 & P=0.7575, respectively). When compared to the control group (103.95±36.67 ng/mL; 403.03±1.03), COVID-19 patients had non-significantly raised levels of CALP and BAFF (106.5±4.67 ng/mL; 436.9±12.77 pg/mL, respectively). According to ROC curve analysis, the area under the receiver operating characteristics curve (AUC) for CALP and BAFF was (0.5170) and (0.5259), respectively. (r=0.6923; P=0.0001). There was a significant positive correlation between serum CALP and BAFF levels. The connection between serum CRP levels and CALP (r=0.3010; P=0.1271) and BAFF levels (r=0.2912; P=0.1406) was insignificantly positive.
Conclusion: The current study's findings suggested that serum CALP and BAFF concentrations were increased in COVID-19 patients, suggesting that these inflammatory markers may be helpful indicators of the severity of COVID-19.
Análise da produção do conhecimento na área da avaliação da qualidade da educação superior nos Grupos de Estudos e Pesquisas sobre Educação Superior (GEPES)
Authors: Guerra Margareth Da Silva , Lima Lucas Borges de , Rocha Elielson Borges da 
Published: July 2023

Neste artigo, um recorte da produção acadêmica, trata-se do campo das políticas de avaliação e asseguramento da qualidade da educação superior nos Grupos de Estudos e Pesquisas sobre a Educação Superior (GEPES), visando identificar movimentos de resistência epistemológica com produção de diferentes cosmovisões contra-hegemônicas. A coleta de dados foi feita no Banco de Dados da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), combinada com o diretório dos grupos de pesquisa do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPQ). Os dados revelam que os estudos consultados norteiam as entrelinhas da hegemonia, da meritocracia, do produtivísmo, evidenciando a significativa importância dos movimentos de resistência epistemológica na produção de diferentes cosmovisões contra-hegemônicas.
ANALISIS BUTIR SOAL USBN MATA PELAJARAN BAHASA INDONESIA DI SMA KABUPATEN ACEH BARAT
Authors: Lasmy Lasmy , Yusrizal Yusrizal , Razali Razali 
Published: July 2023

This study aims to find out the validity, reliability, difficulty level, differentiation, and function item problem of USBN casting in Bahasa Indonesia subjects at SMA Aceh Barat. The approach in this study is a quantitative approach. This research uses a type of quantitative descriptive research. The sample of this study amounted to 5 schools and this research data is 40 question from the answer sheet of 50 students in each school. Data collection techniques with document studies. The data analysis techniques in this study used the AnatesV4.02 program. Analysis of problem items with a computer is a quantitative review of the question item whose calculations use the anates V4.02 application. The results of this study showed that the validity of USBN problems in Bahasa Indonesia subjects at SMA Aceh Barat district obtained 74valid questions with a validity level of 0.32-0.40 and 126 invalid questions with a degree of invalidity of 0.20. This invalidity is caused by the inaccuracy of explanation of each material by the teacher in the school so that students are unable to understand about the essence of the sentence. Reliability of USBN subjects in Bahasa Indonesia at SMA West Aceh district shows 0.61-0.73 in high reliability category. High school that gained the low reliability category was SMA Woyla of value 0.31. This is because the low understanding of students so as to cause problems classified in is very difficult. The difficulty level of USBN problems in Bahasa Indonesia subjects in SMA Kabupaten Aceh Barat can be seen from the difficulty index between 0.00 to 1.0. The degree of difficulty that dominates the difficulty level in each question studied is in the moderate category. The difficulty of this medium problem is influenced by the inaccuracy of the material provided by the teacher so that the student is not able to understand it completely. In addition, the question that is used as an evaluation is born from materials that are not taught by the teacher. The differentiation of USBN subjects in Bahasa Indonesia at SMA Aceh Barat district shows the percentage value includes a very good differentiation question 2 questions, good 56 questions, enough 71, and bad 71 questions. A series of differentiating power quality levels of this question appears that the differentiation of problems with very good quality is less compared to the quality of the differentiation of the problem with the category of good, sufficient, and bad. This quality difference because each question does not go through a validation and reliable process so as to have an effect on the differentiating power of each question. The casting function of USBN subjects in Bahasa Indonesia at SMA Aceh Barat consists of five levels including very good
MAKNA KIDUNG SINGGAH-SINGGAH PADA RITUAL BEDHOL PUSAKA SATU SURO DI PONOROGO
Authors: A. Madani  , N.W. Sartini  , D. Mayangsari  , P.K. Hadi  
Published: July 2023

Penelitian ini merupakan kajian etnolinguistik yang bertujuan untuk menganalisis makna Kidung Singgah-Singgah yang terdapat dalam ritual Bedhol Pusaka Satu Suro di Ponorogo. Ritual Bedhol Pusaka merupakan bentuk napak tilas atau mengenang terbentuknya Ponorogo. Ritual ini dilakukan dengan mengambil tiga pusaka Bathoro Katong, pendiri sekaligus adipati pertama Ponorogo. Pengumpulan data dilakukan menggunakan metode simak dengan teknik rekam dan teknik catat. Sumber data instrumen penelitian berupa data lisan dan tulisan yang diperoleh melalui informan yang terlibat dalam penelitian, yaitu pelaku ritual tersebut. Data lisan berupa Kidung Singgah-Singgah yang dituturkan dalam ritual tersebut. Analisis data menggunakan metode kontekstual melalui konteks turunan penutur dengan lawan tutur. Penelitian ini mengkaji Kidung Singgah-singgah yang dilantunkan oleh pelaku ritual tersebut dengan memfokuskan pada aspek makna. Adapun metode penyajian hasil menggunakan metode deskriptif, formal, dan informal. Teori yang digunakan adalah makna konseptual dan asosiatif Geoffrey Leech. Hasil penelitian menunjukkan bahwa Kidung Singgah-Singgah menggunakan tiga bahasa yakni bahasa Jawa, Jawa Kuno, dan Arab. Adapun jenis makna yang ditemukan dalam Kidung Singgah-Singgah terdapat makna asosiatif, yaitu makna konotatif, afektif, kolokatif, dan reflektif. Namun jenis makna yang mendominasi adalah makna konotatif dan afektif yang terdapat pada keempat bait kidung. Secara keseluruhan, makna Kidung Singgah-Singgah tersebut yaitu sebagai upaya tolak bala dan mengingatkan manusia untuk selalu mengingat dan menyembah Tuhannya.