bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of HRCT pattern on six-minute walk test in patients with interstitial lung disease—An observational study
Authors: Saxena Puneet , Singh Itishree , Kumar Abhishek , Kartik S , Malik Virender , Tiwari Saurabh , Akhil KR , Pattanayak Somali , Velangi Vaibhavi G. , Jain Harsh 
Published: August 2023

ABSTRACT

Background:
Forced vital capacity (FVC) and six-minute walk distance (6MWD) are robust markers in interstitial lung diseases (ILD) to assess severity and prognosis. It is unknown whether high-resolution computed tomography pattern has any independent effect on the exercise capacity in ILD. We compared six-minute walk test (6MWT) parameters between usual interstitial pneumonia (UIP) and non-UIP ILD after adjusting for FVC.

Methods:
Data from a tertiary care ILD clinic were retrospectively analysed. Based on HRCT, patients were classified as UIP and non-UIP. 6MWT parameters and FVC were recorded for enrolled patients. 6MWD, distance-saturation product (DSP) and exertional desaturation were compared between UIP and non-UIP, using analysis of covariance (ANCOVA), with per cent predicted FVC as covariate. Patients were grouped as mild (≥70%), moderate (51%–69%) and severe (≤50%) based on FVC severity.

Results:
Out of 169 patients enrolled, only patients with all three data points: spirometry, 6MWT and HRCT were included in the analysis (n = 139). UIP group comprised 56 (40.3%), while non-UIP group had 83 (59.7%) patients. More females and lesser smokers were present in non-UIP group. Mean predicted FVC% was similar between the two HRCT groups (P = 0.611) and had a statistically significant, though very weak to weak correlation with 6MWT parameters {6MWD (r = 0.138); pred 6MWD% (r = 0.170); desaturation (r = -0.227); DSP index (r = 0.166)}. Analysis of covariance showed no statistically significant difference in the 6MWT parameters between UIP and non-UIP groups for similar FVC levels.

Conclusion:
For a similar level of lung function, exercise capacity was similar for patients with UIP and non-UIP pattern ILD.
A complete spectrum of congenital cystic adenomatoid malformation of the lung deceptive clinical presentations and histological surprises; a single institutional study from a tertiary care hospital in North India
Authors: Walvir Nazia Manzoor , Makhdoomi Rumana , Abeer Inara , Ganaie Farooq , Maqsood Shadab 
Published: August 2023

ABSTRACT

Background:
Congenital Cystic Adenomatoid Malformations (CCAM) are rare congenital anomalies of the lungs characterised by bronchopulmonary foregut malformations due to a sudden arrest in the development of the bronchial tree in the first trimester of the gestational period.

Aim:
The present study was aimed to describe the clinical and histopathological profiles of the patients and study patient outcomes after 1 year of surgical resection.

Methods:
All patients diagnosed with CCAM by histological examination of tissue obtained on surgical resection during the study period were included in the study. Data, such as patient demographics and clinical, radiological and histopathological findings, were recorded, and follow-up information was taken on OPD follow-up till 1 year after surgery regarding respiratory infections, haemoptysis or mortality.

Results:
Out of 21 patients, 11 were female and included in the study between the ages of 1 month and 32 years, with >50% younger than 2 years. Most patients in the study had recurrent pneumonia, with difficulty in breathing being the second most common presenting complaint. All patients had undergone computed tomography (CT) of the lungs, which was able to diagnose cystic lesions accurately in >80% of cases. Histologically, all cases were classified based on recent Strocker’s classification, and Type 1 was the most commonly observed with 13 cases, followed by Type 2 in five and Type 3 in three patients. There was no evidence of malignant transformation in any of the cases. There was 100% survival at the end of 1 year, with six patients having respiratory infections and none of the patients getting hospitalised over 1 year after surgery.

Conclusion:
CCAM is a rare congenital anomaly associated with significant morbidity and may present at any age. It can be histologically classified into three subtypes, with Type 1 being the most common. Early surgical management is mandatory to prevent complications such as recurrent infections, respiratory distress, pneumothorax, lung abscess and malignant transformation. All patients included in the study had undergone surgical resection, and there was 100% survival at 1-year follow-up.
Association between 25-hydroxy vitamin D and lung function (FEV1, FVC, FEV1/FVC) in children and adults with asthma: A systematic review
Authors: Abi-Ayad Meryem , Nedjar Imane , Chabni Nafissa 
Published: August 2023

ABSTRACT
Asthma is a chronic respiratory disease that poses significant individual, social, financial and healthcare burdens. Physicians and researchers have recommended 25-hydroxy vitamin D supplementation, in combination with prescribed medication, as a potential means of reducing asthma severity. This systematic review focuses on the association between 25-hydroxy vitamin D levels and lung function in both children and adults with asthma. We identified published work by searching MEDLINE via PubMed, using regular search terms related to 25-hydroxy vitamin D and asthma. Fourteen studies were screened out of 643 eligible citations from MEDLINE research that involved 65 children and 951 adults. A strong positive association was observed in four studies, whereas five showed a moderate association, and two had no correlation. The majority of studies found a negative correlation between 25-hydroxy vitamin D deficiency and mild, uncontrolled and partly controlled asthma. 25-hydroxy vitamin D 25 OH values were below 20 ng/ml in the majority of studies, and those with uncontrolled severe asthma showed the lowest values.
Safety, utility and clinical efficacy of cryobiopsy of lung in paediatric population—A single centre experience
Authors: Chandra Tejaswi , Srikanta J. T , Madhusudan Manoj , Mohite Kaustubh , Arigela Karthik 
Published: August 2023

ABSTRACT

Background:
Surgical lung biopsy (SLB) or video-assisted thoracic surgery (VATS) has been the traditional gold standard modality for diagnosing paediatric interstitial lung diseases. Cryobiopsy of the lung has recently been shown to be a novel technique with very good sensitivity and specificity in the diagnosis of various interstitial lung disorders in adults. Although there are a few case reports of the same in children, pediatric cryo lung biopsies are rarely performed due to the lack of the necessary equipment and the lack of expertise.

Methods:
A retrospective single-centre study was conducted with twelve consecutive children with diffuse parenchymal lung disease diagnosed both clinically and on high-resolution computed tomography (HRCT) of the chest which were included in the study between October 2020 and September 2022 to measure the diagnostic yield and safety of the procedure. The site from where cryobiopsy was to be done was chosen after a multidisciplinary meeting with the paediatric radiologist.

Results:
Twelve children (eight males and four females) were included in the study who underwent a cryobiopsy in the duration of two years. The mean age of the cases involved was 8 years and 3 months. With the youngest and oldest being 12 days and 15 years, respectively, all children underwent cryobiopsy as mentioned above. Diagnostic yield was achieved in 92% of cases.

Conclusion:
Cryobiopsy is a valuable diagnostic tool in childhood interstitial lung diseases, which offers a less invasive option for obtaining lung tissue samples with a better yield which can aid in accurate diagnosis, a good safety profile and a shorter hospital stay. Our study emphasizes that in trained centres, TBCB is a safe, effective and less invasive way to obtain tissue diagnosis in children with ChILD.
Primary pulmonary botryomycosis. Report of a case and literature review
Authors: Benavides-Huerto Miguel A. , Mier-Briseño Antonio , Lagunas-Rangel Francisco A. 
Published: August 2023

ABSTRACT
Botryomycosis is a rare chronic suppurative infection characterised by a granulomatous inflammatory response to bacterial pathogens. Among the two forms, the visceral form is an even rarer finding that mainly affects the lungs and whose main causative agents are Staphylococcus aureus and Pseudomonas aeruginosa, although many other non-filamentous bacteria have been identified. Here, we present a case of primary pulmonary botryomycosis, which to our knowledge is the first case of this type reported in Mexico. In addition, we review the 18 cases of primary pulmonary botryomycosis reported in the literature, where we focus on evaluating the clinical characteristics, predisposing factors, causative agents and treatments used in these patients. This helps physicians to improve the differential diagnosis of this disease.
Clinico-cytological Analysis of Conjunctiva and Ocular Surface Symptoms of Patients on Topical Anti-glaucoma Medications Attending Lagos University Teaching Hospital, Lagos, Nigeria: A Case–Control Study
Authors: Aribaba Olufisayo Temitayo , Adenekan Olusesan Adetunji , Alabi Adegboyega Sunday , Aina Mobolaji Taiwo , Anunobi Charles Chidozie , Onakoya Adeola Olukorede 
Published: August 2023

Background:
The long-term use of topical anti-glaucoma medications is often associated with ocular surface toxicity that can affect the patient’s drug compliance and quality of life. This study assessed the effect of these medications, using cytological changes of the conjunctiva and ocular surface symptoms.

Materials and Methods:
This was a clinic-based, case–control study that was conducted at the Lagos University Teaching Hospital that compared glaucoma patients on topical medications with age–sex-matched controls. The controls were non-glaucoma patients, who were not on any topical ocular medications at least 6 months prior to the study. The Ocular Surface Disease Index (OSDI) questionnaire was used to assess ocular surface symptoms. Schirmer’s I test, tear film break-up time (TBUT) test and corneal fluorescein staining of the ocular surface were used for ocular surface disease (OSD) assessment and conjunctival impression cytology (CIC) for histological assessment and grading.

Results:
Six hundred and ninety-six eyes of 348 respondents, 174 cases and 174 controls, were assessed for OSD. The mean ages of the case and control groups were 56.3 ± 12.9 years and 55.5 ± 13.2 years, respectively, with no statistical difference (P = 0.589). All ocular parameters assessed were significantly abnormal in the case group compared to the control group. The use of topical anti-glaucoma medications was significantly associated with abnormal TBUT (P < 0.001), Schirmer’s test (P < 0.001), ocular surface staining (P < 0.001), CIC (P < 0.001) and OSDI scores (P = 0.001). A significant association was seen between abnormal TBUT and the number of medications (P = 0.044, odds ratio [OR] =0.79, 95% confidence interval [CI]: 0.44–1.14), between abnormal ocular surface staining and duration of anti-glaucoma medications usage (P = 0.0104, OR = 1.2, 95% CI: 1.04–1.43) and between abnormal CIC and the duration of anti-glaucoma medications (P = 0.0007, OR = 0.7, 95% CI: 0.59–0.86).

Conclusion:
The study demonstrates that prolonged use of topical anti-glaucoma medications may be associated with damage to the ocular surface structures.
COVID-19 in 16 West African Countries: An Assessment of the Epidemiology and Genetic Diversity of SARS-CoV-2 after Four Epidemic Waves
Authors: Ndiaye Anna Julienne Selbé , Beye Mamadou , Sow Aissatou , Lo Gora , Padane Abdou , Sokhna Cheikh , Kane Coumba Touré , Colson Philippe , Fenollar Florence , Mboup Souleymane , Fournier Pierre-Edouard 
Published: August 2023

ABSTRACT.
West Africa faced the COVID-19 pandemic in early March 2020 and, as of March 31, 2022, had more than 900,000 confirmed cases and more than 12,000 deaths. During this period, SARS-CoV-2 genomes evolved genetically, resulting in the emergence of distinct lineages. This review was conducted to provide the epidemiological profile of COVID-19, the mutational profile of SARS-CoV-2, and the dynamics of its lineages in the 16 west African countries by analyzing data from 33 studies and seven situation reports. For a more complete representation of the epidemiology and genetic diversity of SARS-CoV-2, we used reliable public data in addition to eligible studies. As of March 31, 2022, the 16 west African countries experienced four epidemic waves with variable intensities. Higher mortality was noted during the third wave with a case fatality rate (CFR) of 1.9%. After these four epidemic waves, Liberia recorded the highest CFR (4.0%), whereas Benin had the lowest CFR (0.6%). Through mutational analysis, a high genetic heterogeneity of the genomes was observed, with a predominance of mutations in the spike protein. From this high mutational rate, different lineages emerged. Our analysis of the evolutionary diversity allowed us to count 205 lineages circulating in west Africa. This study has provided a good representation of the mutational profile and the prevalence of SARS CoV-2 lineages beyond the knowledge of the global epidemiology of the 16 African countries.
DIGITALIZED BRIEFS: REFRAMING THE INFLUENCE OF THE DIGITAL ENVIRONMENT ON READERS' ENGAGEMENT WITH FLASH FICTION
Authors: Rahmeh Hassan 
Published: August 2023

The proliferation of digital platforms has redefined readers' engagement patterns, especially with concise narratives like flash fiction This research delves into a thorough analysis of the distinctive characteristics of flash fiction, a form that is currently gaining popularity and widespread acceptance due to the enjoyment it gets from the digital environment. Embracing the essence of brevity, flash fiction thrives on conciseness and magnetizes its audience within a limited word count. With the advent of digital platforms and technological advancement, the boundaries of traditional storytelling have expanded, providing a fertile and dynamic environment for the growth of flash fiction. The research employs an interdisciplinary approach, interweaving threads from psychology, media analysis, and literary criticism to investigate the specific aspects of the digital milieu that are crucial to the heightened engagement and enjoyment felt by flash fiction enthusiasts. This study seeks to shed light on the fundamental mechanisms that contribute to the magnetic pull of flash fiction in the digital domain by analyzing a variety of dimensions, including interaction, accessibility, social connection, and creativity. A fundamental component of this exploration is to unravel the core processes that elevate the appeal of flash fiction in the digital world. By dissecting these aspects, the research illuminates how the combination of these factors works in unison to enhance the charm of flash fiction in the digital age.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0049/a.php" alt="Hit counter" /></p>
Implementasi Undang-Undang Nomor 30 Tahun 1999 tentang Arbitrase dan ADR
Authors: Ramdhany Memmy Fatiyanti Deri 
Published: August 2023

Penelitian ini bertujuan untuk mengetahui Alternatif Penyelesaian Sengketa (APS) adalah penyelesaian sengketa yang diluar pengadilan sesuai dengan kesepakatan para pihak yang dilakukan dengan cara konsiliasi, mediasi, negosiasi dan penilaian ahli. Hal ini tertuang dalam UU No. 30 Tahun 1999, sedangkan terkait mekanisme upaya penyelesaian menggunakan alternatif penyelesaian sengketa. Jenis penelitian hukum yang dilakukan adalah penelitian yuridis, yang menggunakan pendekatan peraturan perundang-undang, hasil penelitian menunjukkan bahwa implementasi UU No. 30 Tahun 1999 terimplementasi dengan baik dalam melaksanakan upaya penyelesaian sengketa, Hasil dari permasalahan kedua yaitu, peneliti menemukan ada beberapa aturan yang dapat menjadi dasar hukum pemberlakuan Mediasi Penal di Indonesia. Beberapa peraturan perundang-undangan tersebut dapat menjadi rujukan dalam membantu kerja-kerja penegak hukum dalam menyelesaikan perkara pidana. permaafan yang ada di dalam masyarakat. Praktek penyelesaian perkara pidana di luar pengadilan selama ini tidak ada landasan hukum formalnya (norma kosong). Sering terjadi suatu kasus yang secara informal telah ada penyelesaian damai, namun tetap saja diproses ke pengadilan sesuai hukum yang berlaku.
Effective and aesthetic results of horizontal right axillary minithoracotomy for congenital heart defects repair in children
Authors: Nguyen Sinh Hien , Nguyen Huu Phong , Nguyen Dang Hung , Dang Quang Dai , Nguyen Hai Dang , Nguyen Thi Minh Phuong 
Published: August 2023

Background: horizontal right axillary minithoracotomy is one of the treatment options for many simple congenital heart defects. This approach shows many aesthetic advantages besides effectiveness and safety. This study aims to: comment on the technical characteristics and early results of horizontal right axillary minithoracotomy in children at Hanoi Heart Hospital.
Methods: a descriptive cross-sectional study. We retrospectively reviewed 156 patients who underwent horizontal right axillary minithoracotomy at Hanoi Heart Hospital from January 2022 to December 2022.
Results: horizontal axillary approach could be applied even for children with low weight, average weight was 12.22 ± 8.67 kg, the lowest was 2.6 kg and the highest was 51.0 kg. A wide range of congenital heart defects were repaired, including ventricular septal defect closure (84 patients), secundum atrial septal defect closure (22 patients), ventricular septal defect with stenosis repair (31 patients), partial atrio-ventricular septal canal repair (6 patients), repair of atrial septal defect with partial abnormal return of the pulmonary veins (3 patients), repair of ventricular septal defect and atrial septal defect (4 patients), Cor triatriatum sinister repair (4 patients), mitral valve repair (1 patient), atrial septal defect and pulmonary valve stenosis repair (1 patient). Cannulation of the aorta and vena cavae was performed through the main incision, whose size ranged from 3.5 to 5.5cm. The average postoperative hospital stay was 7.34 ± 2.16 days, the rate of severe complications and hospital mortality were 0%.
Conclusion: horizontal right axillary minithoracotomy was a good approach to correct many simple congenital heart defects in children. This technique is being applied at Hanoi Heart Hospital safely and provided outstanding advantages in terms of aesthetics.
Micro-CT Evaluation of Centering Ability and Canal Transportation of Protaper Ultimate and RevoS+ Rotary File Systems in Simulated Curved Canals
Authors: BÜYÜKSUNGUR Arda , ONCU Aysenur , CELİKTEN Berkan , HUANG Yan 
Published: August 2023

Purpose
A successful root canal preparation is to remove infected dentin and pulp tissue and to obturate the canal three-dimensionally. This study aimed to compare the centering ability of Protaper Ultimate and RevoS+ rotary file systems in curved canals of printed mandibular first molars by using micro-computed tomography (micro-CT).
Materials and Methods
In this in-vitro study, 16 mandibular molar teeth were printed from resin with 45° mesial root curvature. Root canal preparation was performed according to the specified groups, either Protaper Ultimate or RevoS+. The pre-and post-preparation images were repositioned in all three spatial planes by DataViewer. All images were imported into the CTAn software for the calculation of the centering ability and transportation values.
Results
The results showed no significant differences between the Protaper Ultimate and RevoS+ groups in terms of the centering ratio in the most inclined part of the canal. There were also no significant differences between the groups in canal transportation. (p>0.05)
Conclusions
Protaper Ultimate and RevoS+ rotary file systems showed similar ability in centering ratio and canal transportation in curved canals from printed mandibular molars.
A Arte urbana e o Turismo: uma proposta contradiscursiva sobre as práticas artísticas no espaço público urbano e os impactos do turismo
Authors: Goes Diogo 
Published: August 2023

A intervenção artística no espaço público urbano, no uso de um discurso específico sobre arte contemporânea e do exercício de práticas curatoriais, carece de uma identificação com o "lugar" - espaço habitado e vivencial, no qual se criam hábitos - e com a sua envolvente situacional e social, bem como, do reconhecimento de um contexto identitário, histórico e social, subjacente à especificidade do desenvolvimento urbano herdado e sobre aquele que se projeta para o futuro, da pós-intervenção. Não sendo consensual, todas as diferentes perspetivas possíveis, sobre a consideração de hipóteses de uma objetualização da intervenção artística, num sentido utilitário dessa intervenção, é de extrema importância que as mesmas sejam as mais adequadas e de acordo com um referencial histórico e cultural, adequado à especificidade de cada "lugar" ocupado, território de Turismo. Torna-se fundamental contextualizar cada intervenção, tida por artística, com outras práticas discursivas sobre o espaço público, ao nível internacional, mais bem-sucedidas, verificando os impactos, se existentes no turismo e nas áreas conexas. Pretende-se analisar, não só uma "pura" vertente da intervenção artística, no seu enquadramento conceptual e de revisão bibliográfica das melhores práticas em termos da Arte, mas também analisar os diferentes impactos que a mesma produz no turismo cultural das cidades e no desenvolvimento social e humano na sociedade onde está inserida. Concluiu-se que arte no espaço público urbano está intimamente ligada a um discurso político que procura contemporanizar as cidades, de modo a constituí-las como marca global e polo de atração turística. Para isso a arte no espaço público urbano, tem vindo a ser interpretada não pela sua capacidade discursiva, mas pelo deleite estético, não respondendo por isso às reais necessidades de reabilitação urbana quer no domínio arquitetónico, quer no social. Conclui-se que, por hipótese, a arte ao tentar responder às premissas do Turismo, autodetermina-se subvertendo a lógica da sua conceção e em vez de potenciar a inclusão social, poderá tornar-se fator de exclusão.
THEORETICAL FOUNDATIONS OF THE DEVELOPMENT OF A BULLDOZER DESIGN THROUGH THE USE OF MULTIVARIATE PARAMETRIC ANALYSIS
Authors: Suleev Bakhtiar , Kurmasheva Bakyt 
Published: August 2023

The article presents the scope, purpose and design of the bulldozer. The main brands of bulldozers used in our republic are given. Their main characteristics are considered, such as: weight, power, blade width and blade height. As a result of the analysis of parametric information, the standard deviation, average value, coefficient of variation, asymmetry and kurtosis were determined. A correlation matrix has been compiled that describes the relationship between the parameters of the machines. Based on the results obtained, a cluster analysis was carried out in the StatGraphics Centurion software. A histogram of the distribution of bulldozer indicators is constructed, with the determination of the left and right boundaries, and the number of models in the interval. Using the obtained parametric analysis data, the equations for determining the coefficient of the technical level were formed. Using the obtained equation, the coefficient of the technical level and the prospective values of the machine parameters are determined.