bluuebunny/crossref_metadata_2025_split huggingface dataset:
Circulating Brain Injury Biomarkers: A Novel Method for Quantification of the Impact on the Brain After Tumor Surgery
Authors: Michaëlsson Isak , Hallén Tobias , Carstam Louise , Laesser Mats , Björkman-Burtscher Isabella M. , Sörbo Ann , Blennow Kaj , Zetterberg Henrik , Jakola Asgeir S. , Skoglund Thomas 
Published: May 2023

BACKGROUND:
Clinical methods to quantify brain injury related to neurosurgery are scarce. Circulating brain injury biomarkers have recently gained increased interest as new ultrasensitive measurement techniques have enabled quantification of brain injury through blood sampling.

OBJECTIVE:
To establish the time profile of the increase in the circulating brain injury biomarkers glial fibrillary acidic protein (GFAP), tau, and neurofilament light (NfL) after glioma surgery and to explore possible relationships between these biomarkers and outcome regarding volume of ischemic injury identified with postoperative MRI and new neurological deficits.

METHODS:
In this prospective study, 34 adult patients scheduled for glioma surgery were included. Plasma concentrations of brain injury biomarkers were measured the day before surgery, immediately after surgery, and on postoperative days 1, 3, 5, and 10.

RESULTS:
Circulating brain injury biomarkers displayed a postoperative increase in the levels of GFAP (P < .001), tau (P < .001), and NfL (P < .001) on Day 1 and a later, even higher, peak of NFL at Day 10 (P = .028). We found a correlation between the increased levels of GFAP, tau, and NfL on Day 1 after surgery and the volume of ischemic brain tissue on postoperative MRI. Patients with new neurological deficits after surgery had higher levels of GFAP and NfL on Day 1 compared with those without new neurological deficits.

CONCLUSION:
Measuring circulating brain injury biomarkers could be a useful method for quantification of the impact on the brain after tumor surgery or neurosurgery in general.
Methodological systems for the preparation and holding of Olympiads and the development of students' intellectual abilities RTU MIREA
Authors: Vyshnyepolskiy Vladimir , Kadykova Nina , Efremov A. , Egiazaryan K. 
Published: May 2023

The paper considers a methodological system for the development of students' intellectual abilities in the process of preparing for Olympiads in descriptive geometry. In accordance with this system, a detailed calendar plan for conducting training sessions for the regional Olympiad in descriptive geometry is presented.
The paper is also about the methodological system for preparing and holding a university, city and regional student Olympiads in graphic disciplines. The requirements for the choice of tasks for university Olympiads in descriptive geometry, instructions for holding university Olympiads are given.
The paper provides information, including historical information, about the Moscow City Olympiad in descriptive geometry, engineering and computer graphics. To assess the level of organization of city and regional student Olympiads, in particular, the Moscow City Olympiads, a criterion and dependence for its determination are proposed.
It was proposed the determination method of the composition of the university team for participation in the regional Olympiad in descriptive geometry is proposed based on four criteria: 1) the sum of points received for solving Olympiad tasks of previous years in the classroom; 2) the sum of points received for solving homework tasks; 3) the sum of points for two rounds of the University Olympiad; 4) integral indicator.
The methodological system of preparation and holding of the All-Russian student Olympiads in graphic disciplines is considered. To assess the level of organization of the All-Russian Student Olympiad, a criterion is proposed, which is determined by the sum of four parameters: 1) the number of participating universities; 2) the number of participating students divided by ten; 3) the number of subjects of the Russian Federation (regions) represented at the Olympiad; 4) the number of federal districts of the Russian Federation represented at the Olympiad.
The All-Russian Student Olympiads in graphic disciplines, which have been held by RTU MIREA since 1999 (until 2015, Moscow State University of Fine Chemical Technologies named after M.V. Lomonosov), are briefly considered. It was noted that 83 universities from the Russian Federation and one foreign university took part in these Olympiads.
Scientific Research at the Department of Engineering Graphics RTU MIREA
Authors: Vyshnyepolskiy Vladimir , Boykov A. , Egiazaryan K. , Efremov A. 
Published: May 2023

Involving students in scientific activities is an important stage in the development of a future scientist. At the same time, the main difficulty is the need to interest the student. One of the factors that can generate such interest is to ensure the spirit of competition in the first attempts at scientific work. To do this, the Department of Engineering Graphics holds two sections in the Scientific and practical conference of students and graduate students of the
RTU MIREA: : "Smart Home", for students of radio engineering specialties, where students are engaged in the design and implementation of prototypes of various radio engineering devices and sensors, and "Descriptive Geometry", for students of all areas of education, where they present their projects to the jury both in the field of research of academic geometric knowledge, as well as in the field of their practical application. The authors of the best projects presented in the sections are given the opportunity to speak at the All-Russian Student Competition "Innovative Developments", which is also organized by the Department of Engineering Graphics as part of the All-Russian Student Olympiad for Students in Descriptive Geometry, Engineering and Computer Graphics. For half a year between these events, students correct the project in accordance with the comments made by the jury, and if there are unrealized plans, they finalize them. The next stage in the development of students - participants of the above-mentioned conference and Competition - is the preparation of a scientific article based on their work in journals indexed in the RSCI. The student gains experience in preparing an articles, after which, as a rule, scientific work continues, and the student takes part in various scientific conferences with reports, where he gains experience in speaking to an audience and interacting with it, and also, under the guidance of a supervisor, prepares a scientific article or a number of articles in peer-reviewed scientific journals, while gaining experience in communicating with reviewers and correcting their comments on the work. This experience gives the student the skill of independence in further scientific work
Where to Cut the Long Tail? The Value of Carrying Inventory in Online Retail
Authors: Baldauf Christoph , Eng-Larsson Fredrik , Isaksson Olov 
Published: May 2023

One advantage of online retail is that a large number of products can be displayed at low cost. However, online retailers must decide which of these products to carry in inventory (stock items) and which to order from suppliers when a customer places an order (nonstock items). In this paper, we empirically investigate how carrying a product in inventory affects its online sales. We use data from a European furniture and interior design retailer consisting of daily sales transactions and inventory data covering 18 months. We use a quasi-natural experiment—random transitions of products in and out of inventory at the retailer’s central warehouse—to estimate the causal effect of carrying inventory on sales. Our results show a strong and statistically significant increase in sales of, on average, 65% associated with having the product available in stock. More interestingly, this effect differs between products and is moderated by the price of the product: sales of more expensive products are less sensitive to the product being in stock. We use these results to draw insights on which types of items to carry in inventory. This paper was accepted by Victor Martínez-de-Albéniz, operations management. Supplemental Material: Data are available at https://doi.org/10.1287/mnsc.2023.4777 .
Consumer Tax Credits for EVs: Some Quasi-Experimental Evidence on Consumer Demand, Product Substitution, and Carbon Emissions
Authors: He Cheng , Ozturk O. Cem , Gu Chris , Chintagunta Pradeep K. 
Published: May 2023

Governments worldwide have spent billions of dollars on monetary incentives for consumers to encourage the adoption of eco-friendly (“green”) products. However, there is little consensus on the effectiveness of delayed monetary incentives with complex structures, such as tax credits in increasing green product adoption and reducing carbon emissions. The literature is also limited on the mechanisms through which monetary incentives work in general. We address these issues by studying the impact of tax credit incentives on green and nongreen vehicle sales in the U.S. auto industry. A tax credit incentive could boost green vehicle sales through cost savings on the vehicle’s price. However, the incentive may prove ineffective because of important barriers to adoption (e.g., long charging times for electric cars). To measure the sales and emissions impacts of tax credits, we study incentive changes in South Carolina and Oregon via various quasi-experimental approaches and assess the generalizability of our key findings to Colorado. Unlike recent studies showing an insignificant or negative correlation between tax credits and electric vehicle adoption, our analyses show that unit sales of incentivized plug-in hybrid electric vehicles (PHEVs) increase by an average of 3.7% (up to 52.7% in some counties) following a $2,000 incentive. In contrast, PHEV sales remain unchanged after the incentive’s termination, implying a positive net sales effect. We also explore the underlying mechanisms for the incentive’s impact by examining various purchase funnel stages. In the awareness stage, the incentive’s positive effect on PHEV demand peaks around the consumers’ tax-filing period. As for the consideration stage, our analyses of online consumer search indicate that the incentive does not expand the consumer pool considering PHEVs. In the conversion stage, the incentive generates more sales for PHEVs in counties where (i) consumers are more likely to have PHEVs in their consideration sets regardless of the incentive (i.e., Democratic counties) and (ii) consumers value cost-saving more (i.e., counties with lower middle income). Also, the heightened demand for PHEVs following the incentive stems from the substitution from gasoline vehicles with high fuel efficiency. We estimate the average cost of reducing carbon emissions through tax credits to be $109 per ton, which is less expensive than tax rebates for conventional hybrids and subsidies for residential solar panels. This paper was accepted by David Simchi-Levi, Special Section of Management Science on Business and Climate Change. Supplemental Material: The online appendix and data are available at https://doi.org/10.1287/mnsc.2023.4781 .
The relationship between psychology practice and complementary medicine in Australia: Psychologists’ demographics and practice characteristics regarding type of engagement across a range of complementary medicine modalities
Authors: Thomson-Casey Carrie , McIntyre Erica , Rogers Kris , Adams Jon 
Published: May 2023

IntroductionMany people with mental health problems utilise a range of complementary medicine (CM) practitioners, products, and practices. Psychologists are likely to consult with clients who are seeking and using CM, in some form, as part of their wider mental health treatment. The aim of this research is to determine how much, and in what ways, Australian psychologists recommend CM products and/or practices, and/or initiate referrals to CM practitioners as part of their clinical practice and to explore if these behaviours have any association with the characteristics of the psychologist or their wider practice.MethodsSurvey data was collected from psychologists in clinical practice who self-selected to participate between February and April 2021. Participation in the study was via an online 79-item questionnaire exploring core aspects of CM engagement in psychology clinical practice.ResultsAmongst the 202 psychologists who completed the survey, mind/body approaches (90.5%) were the most recommended CM and cultural/spiritual approaches the least recommended CM (7.5%). Participants also reported referring to CM practitioners with naturopaths the most common focus of their referrals (57.9%) and cultural and spiritual practitioners the least common focus of their referrals (6.69%). Our analysis shows the demographic and practice characteristics of a psychologist are generally not predictors of a psychologist’s engagement with CM in their clinical practice.ConclusionsSubstantial numbers of psychologists recommend CM products and practices and/or refer clients to CM practitioners. Alongside subjecting CM interventions for mental health to an evidence-base assessment, the broader discipline of psychology needs to also consider psychologist engagement with CM in clinical practice in order to help ensure cultural-sensitivity, client safety and client choice.
Weight loss efficiency and safety of tirzepatide: A Systematic review
Authors: Lin Fei , Yu Bin , Ling Baodong , Lv Guangyao , Shang Huijun , Zhao Xia , Jie Xiaoling , Chen Jing , Li Yan 
Published: May 2023

Objective
Tirzeptide is a novel glucagon-like peptide-1 receptor (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) drug, which shows good efficiency for weight loss. Therefore, we aim to investigate the efficacy and safety of tirzepatide for weight loss in type 2 diabetes mellitus (T2DM) and obesity patients in this meta-analysis study.

Methods
Cochrane Library, PubMed, Embase, Clinical Trials, and Web of Science were searched from inception to October 5, 2022. All randomized controlled trials (RCTs) were included. The odds ratio (OR) was calculated using fixed-effects or random-effects models by Review Manager 5.3 software.

Results
In total, ten studies (12 reports) involving 9,873 patients were identified. A significant loss body weight in the tirzepatide group versus the placebo by -9.81 kg (95% CI (-12.09, -7.52), GLP-1 RAs by -1.05 kg (95% CI (-1.48, -0.63), and insulin by -1.93 kg (95% CI (-2.81, -1.05), respectively. In sub-analysis, the body weight of patients was significantly reduced in three tirzepatide doses (5 mg, 10 mg, and 15 mg) when compared with those of the placebo/GLP-1 RA/insulin. In terms of safety, the incidence of any adverse events and adverse events leading to study drug discontinuation was higher in the tirzepatide group, but the incidence of serious adverse events and hypoglycaemia was lower. Additionally, the gastrointestinal adverse events (including diarrhea, nausea, vomiting and decreased appetite) of tirzepatide were higher than those of placebo/basal insulin, but similar to GLP-1 RAs.

Conclusion
In conclusion, tirzeptide can significantly reduce the weight of T2DM and patient with obesity, and it is a potential therapeutic regimen for weight-loss, but we need to be vigilant about its gastrointestinal reaction.
Are asthma and allergy associated with increased root resorption following orthodontic treatment? A meta-analysis
Authors: Al-Saqi Reem Kais , Athanasiou Athanasios E. , Makrygiannakis Miltiadis A. , Kaklamanos Eleftherios G. 
Published: May 2023

Objective
The aim of this study is to systematically investigate the available evidence from human studies regarding the association of asthma and/or allergy with EARR.

Materials and methods
Unrestricted searches in 6 databases and manual searching were performed up to May 2022. We looked for data on EARR after orthodontic treatment in patients with/without asthma or allergy. Relevant data were extracted, and the risk of bias was assessed. An exploratory synthesis was carried out using the random effects model, and the overall quality of the evidence was assessed with the Grades of Recommendation, Assessment, Development, and Evaluation.

Results
From the initially retrieved records, nine studies met the inclusion criteria (three cohort and six case-control). Overall, increased EARR was observed in the individuals with allergies in their medical history (Standardised Mean Difference [SMD]: 0.42, 95% Confidence Interval [CI]: 0.19 to 0.64). No difference in EARR development was observed among individuals with or without a medical history of asthma (SMD: 0.20, 95% CI: -0.06 to 0.46). The quality of available evidence, excluding studies at high risk, was rated as moderate for the exposure to allergy, and low for the exposure to asthma.

Conclusion
Increased EARR was noted in individuals with allergies compared to the control group, while no difference was observed for individuals with asthma. Until more data become available, good practice would suggest that it is important to identify patients with asthma or allergy and consider the possible implications.
Effect of operators’ proficiency level and patients’ related factors on possible complications, using a high frequency polyamide sonic intracanal irrigation device: A prospective clinical cohort study
Authors: Hahn Tobias , Christofzik David W. , Fawzy El-Sayed Karim , Freitag-Wolf Sandra , Conrad Jonas , Graetz Christian , Größner-Schreiber Birte , Dörfer Christof 
Published: May 2023

ObjectivesSonic/ultrasonic devices are essential tools in today’s endodontics. This prospective trial evaluated for the first time the impact of practitioners’ proficiency levels and patient-related factors on complications associated with a high frequency polyamide sonic irrigant activation device.MethodsIn total 334 patients (females:158, males:176; age:18–95 years) received in the course of their endodontic therapy an intracanal irrigation, using a high frequency polyamide sonic irrigant activation device, by practitioners of different proficiency levels (undergraduate students, general practitioners or endodontists). Intracanal bleeding (yes/no), postoperative pain (0–10 scale), emphysema (yes/no) and polyamide tip fractures (yes/no) were recorded and related to proficiency levels, age, gender, tooth type, smoking-status, systemic conditions affecting healing ability, baseline pain, swelling, fistula, sensitivity to percussion and diagnosis.ResultsIntracanal bleeding was associated with patients’ age (p<0.05), baseline pain level (OR = 1.14, 95%CI = 0.91–1.22) and baseline swelling (OR = 2.73, 95%CI = 0.14–0.99; p<0.05) but not proficiency level, gender, tooth type, smoking, systemic conditions, baseline fistula or sensitivity to percussion (p>0.05). Postoperative pain development was related to proficiency level (p<0.05) and baseline pain level (p<0.001), with no influence of age, gender, tooth type, smoking, systemic conditions, baseline fistula, swelling or sensitivity to percussion (p>0.05). Emphysema and polyamide tip fractures were not reported.ConclusionsWithin the current study’s limitations, younger patients with higher baseline pain and swelling, were associated with higher intracanal bleeding. Apart from higher postoperative pain observed with less experienced practitioners, proficiency level had no influence on bleeding, polyamide tip fracture or emphysema, endorsing the high frequency polyamide sonic irrigation device as a safe therapeutic device.
Juristische Perspektiven auf die Idee der agonistischen Planung
Authors: Durner Wolfgang 
Published: May 2023

Historically, the emergence of planning law and the juridification of planning in Germany did not follow any planning theory, but a logic inherent to the constitutional state. Only in small number of cases did the legislature or the judiciary adopt elements of planning theories, most of which were developed much later. Law defines itself by its strict claim to be obeyed. Therefore, the requirements of planning law may conflict with the recommendations of normative planning theories and then claim precedence over these. Nevertheless, with regard to the viability of some proposals of agonistic planning theories, legal borderlines arise. This paper deals with these borderlines. However, the goal of agonistic theories of planning coincides with the basic function of planning law to pacify conflicting interests and to reach acceptable solutions. Opponents of state planning projects thus are entitled to participate in planning procedures and to file far-reaching lawsuits. However, the legal order also sets limits to legitimate resistance to democratic planning and cannot refrain from distinguishing between legitimate and illegitimate forms of rejection.
Interest Rates, Money, and Fed Monetary Policy in a Markov-Switching Bayesian VAR
Authors: Rich Kenneth M. 
Published: May 2023

Abstract
This paper evaluates the roles of short- and long-term private and government interest rates and inside and outside money in the monetary transmission mechanism. With money and credit markets present, changes in monetary policy set off a chain of relative price and portfolio adjustments affecting output and prices. I study interest rate and money supply rules within this monetary transmission mechanism by estimating several Markov-switching Bayesian vector autoregressions (MS-BVARs) on a quarterly U.S. sample from 1960 to 2018. The best-fit MS-BVAR restricts MS to the impact and lag coefficients of the monetary policy and money demand regressions as well as to the stochastic volatilities (SVs) of the structural shocks. Estimates of this MS-BVAR yield evidence of a SV regime which coincides with NBER-dated recessions. This MS-BVAR also identifies a regime switch in the Fed’s interest rate rule and banks’ demand for outside money around the dot-com bust of 2000 and again from the 2007–2009 recession and financial crisis to the end of the sample. Counterfactual simulations show the 2007–2009 recession and financial crisis would have not been as deep and long-lasting if the fed funds rate had been as low as −8 % in 2009 and remained negative from 2010 through 2016.
Formulaicity and formulaic expressions in Japanese: an introduction
Authors: Shibasaki Reijirou 
Published: May 2023

AbstractFormulaic expressions pervade everyday language. While this has caught the attention of pedagogically oriented researchers due to its benefit in foreign language instruction, the centrality of formulaic expressions in actual language use, along with their emerging nature and plasticity, has only been marginally recognized and thus remains largely unexplored, especially in languages other than English. We propose to fill this gap by highlighting the cognitive and interactional basis of formulaicity in Japanese. We place full weight on formulaic language in actual use, which includes conversational discourse and social networking services such as Twitter posts. Each contribution highlights how formulaic expressions are based on and shaped by usage in context and how they are deployed in unfolding discourse.
The utterance-finaltari siteconstruction in interaction: a general extender as a play stance marker
Authors: Takanashi Hiroko 
Published: May 2023

AbstractRegarding the Japanese utterance-final constructiontari siteas a general extender, this paper discusses the innovative function of this formulaic expression, the non-final form oftari suru‘and/or do’, to mark play stance. I argue that the sequential and interactional context where it is used provides the grounds for this construction to function as such, which contributes to building a play frame intersubjectively. General extenders such as Englishor somethingare highly pragmatic because, by offering a prototypical exemplar that precedes, the speaker invites the listener to infer the implied vague category. My analysis oftari sitein naturally occurring Japanese conversations adds to the existing claim that English fixed expressions are employed to express stances in everyday conversation. Moreover, I found that the play stance markertari siteexpresses the speaker’s positive self-presentation, in contrast to one of the previously claimed general extenders’ functions to convey hedges.