bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of Biosynthesis Silver Nanoparticle on Oxidative Stress Parameters in Model Organism Artemia salina (Linnaeus, 1758)
Authors: ÜNAL İlkay , GÜRKAN selin ERTÜRK 
Published: January 2023

Abstract
As a result of the release of nanomaterials into the ecosystem, the possibility of living things being exposed to these nanostructures has also increased. For this reason, nanotoxicology studies have gained importance. Evaluation of the effects of nanomaterials in various habitats and living groups is increasing with in vitro and in vivo studies. This study aims to describe a biological procedure to synthesize silver nanoparticles using an extract of Marrubium astracanicum and to determine the aquatic environment's oxidative stress on Artemia salina. Silver nanoparticle formation was visually observed with color change. Its structural properties, such as size, shape, morphology, and stability, were characterized by UV-Vis spectrophotometer, TEM, SEM, XRD, and DLS analyses. The effects of biosynthesized silver nanoparticles at different concentrations(control,0.2, 1, 5, 10, 25, and 50 mg/mL) and exposure times (24, 48 and 72 hours) on total glutathione and lipid peroxidation levels were investigated on the Artemia salina organism, which is one of the most common saltwater organisms frequently used in ecotoxicity tests.
Impact of Allopurinol on early and one-year outcomes of patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: A randomized controlled trial
Authors: Daviran Nilgoon , Nateghian Hooman , Separham Ahmad , Ghaffari Samad , Sohrabi Bahram , Aslanabadi Naser , Raadi Mehrdad , Asbagh Amirhosein Ghafouri 
Published: January 2023

Abstract
Purpose: Due to the potential benefits of allopurinol in ischemic reperfusion injury, this randomized control trial was performed to evaluate the pretreatment allopurinol effect on major adverse cardiovascular events (MACE) in patients undergoing primary percutaneous coronary intervention (pPCI).
Methods: A randomized controlled trial was performed on 170 first-time STEMI patients undergoing pPCI. Before the pPCI, patients in intervention group (n=85) received 300 mg dose of allopurinol and control group (n=85) received placebo. Then, for the next 28 days, 100 mg of allopurinol was given to allopurinol group and placebo to the other group. Patients were compared regarding the baseline characteristics, clinical findings and one-year MACE.
Results: Our findings showed that patients receiving allopurinol had significantly longer door-to-balloon time than the control group (60.76 ± 19.38 vs. 50.06 ± 16.38 P-value: 0.001). During one year of follow-up, HF, CVA and mortality occurred more frequently in allopurinol group but differences were not statistically significant. No significant difference was also seen between the two groups regarding MACE during follow-up or hospitalization (p-value: 0.179, 0.330 respectively). Kaplan-Meier curve could not show a significant difference between the two groups in terms of mortality and MACE (P-value: 0.317 and 0.128 respectively).
Conclusion: According to findings of this trial allopurinol had no cardioprotective effect against adverse cardiovascular events or death in patients undergoing pPCI.
Nonlinear Optical Properties of Gold with Intense Femtosecond Laser Excitations above the Damage Threshold
Authors: Wang Zibo , Kan Zhe , Shen Mengyan 
Published: January 2023

Abstract
The nonlinear optical properties of gold thin films have been studied under the irradiation of destructive laser pluses. The transmissivity and the reflectivity of a 100-nm-thick gold film are measured with femtosecond laser irradiations up to 106 J/m2 fluence, which is much higher than the damage threshold of gold. The nonlinearity is calculated with Fresnel loss equations. The real part of the complex refractive index is calculated to have a peak at ~ 10 kJ/m2, which is close to the damage threshold. The complex third-order nonlinear susceptibility χ3 is estimated to be (3.87−6.64𝑖)×10−21𝑚2/𝑉2, which agrees the trend in previous reports that it decreases as pulse duration decreases. This nonlinearity is further studied with a plasmon-photon exchange (PPE) model, where laser induced plasmons and absorbed photons are strongly correlated. The result of the simulation with the PPE model is in good agreement with the experimental transmissivity above the damage threshold. The model predicted an interaction time between photons and plasmons to be about 500 fs. This model is found to be essential in understanding such nonlinear optical processes under both extremely high and conventionally low laser irradiations.
The importance of guided physical activity in the first 48 months: differences in motor skills
Authors: Rebelo Miguel , Serrano João , Paulo Rui , Duarte-Mendes Pedro , Santos Jorge , Honório Samuel , Petrica João 
Published: January 2023

Abstract
Objective: The aim of this study was to verify whether there were differences in the development of motor skills (global and fine) comparing children who have oriented physical activity and children who do not, in day care centers and kindergartens.
Methods: In this study, 400 children of both sexes (28.14 ± 7.23 months) participated. Two groups were created (the group that has oriented physical activity and the group that does not have oriented physical activity) and for a better understanding they were divided into 3 age groups (12-23, 24-35 and 36-48 months). Motor skills were assessed using the PDMS-2 test battery scales. For data analysis we used descriptive and inferential statistics. The Kolmogorov-Smirnov test and the Mann-Whitney test were applied. The method of inferences based on the magnitude of the effects was also performed.
Results: The results obtained indicate that it is only after 36 months that most children practice oriented physical activity, and in all age groups, it is this group that obtains, on average, better results in all motor skills, with greater emphasis in the age group of 24-35 months.
Conclusions: However, the most important conclusion is that it is in the first months (up to 36) that there are greater differences, but it is also where there are fewer children to perform guided physical activity, this is an important factor, to make institutions aware of the importance of physical activity, especially in the first few months, noting that physical activity classes at the day care center are a privileged moment to stimulate fundamental motor skills.
The compared study about femoral stem alignment with or without the special curve rasp during DAA total hip arthroplasty
Authors: Lin Bei , Lan Yiping , Lu Zhiming , Xie Shiwei , Lin Feitai , Weng Yan , Feng Eryou , Chen Jinhua 
Published: January 2023

Abstract
Objective
To investigate whether the application of a curved rasp on the femoral side is effective in reducing the incidence of stem valgus-varus in total hip replacement with direct anterior approach (DA-THA), followed by the analysis of the independent risk factors affecting stem alignment.
Methods
Retrospective analysis was carried out covering 160 patients undergoing DA-THA from January 2019 to December 2021, with Tri-lock (BPS) stem applied in all 120 patients were screened according to inclusion and exclusion criteria. The data of gender, age, body mass index, FAR ratio, pelvic morphology ratio, femoral stem placement angle, use of curved rasp, intraoperative complications, WOMAC scores, were analyzed to explore the independent factors influencing the valgus-varus of the femoral prosthesis implantation. Then data of patients were divided into group A and group B according to whether the curved rasp was taken during the operation. The chi-square test was performed to compare the incidence of femoral malalignment between the two groups.
Results
There revealed two independent risk factors: BMI and FAR score that affected femoral stem alignment. The increased BMI was associated with a higher probability of stem malalignment (p < 0.05), FAR score < 1, with 44.00% of stem malalignment. Further analysis of subgroups revealed a 27.5% incidence of stem malalignment in patients with intraoperative application of curved rasp, the incidence of stem malalignment was significantly increased to 48.8% without curved rasp (p = 0.02). All prosthesis placement angles in group A were more illustrious than group B, especially in the statistically significant differences moderate (9.10%)/severe (8.30%) valgus and varus (p < 0.05). There found no significant difference in intraoperative complications and last follow-up assessment of WOMAC scores between the two groups of patients.
Conclusions
In DA-THA, BMI and FAR act as the independent risk factors for femoral stem malalignment.Intraoperative use of an curved rasp significantly reduces the incidence of malalignment of the femoral stem.
Petrogenesis of juvenile pelletal lapilli in ultramafic lamprophyres: A new type of “melt inclusions”
Authors: Prokopyev Ilya , Doroshkevich Anna , Starikova Anastasia , Kovalev Semen , Izokh Andrey , Nugumanova Yazgul 
Published: January 2023

Abstract
The Chadobets alkaline-carbonatite complex (Siberian craton) is a natural laboratory for all varieties of ultramafic lamprophyres, including damtjernites formed by fluid-explosion mechanisms, which contain a large number of pelletal lapilli. Data obtained from comprehensive mineralogical, structural and chemical studies of these pelletal lapilli show strong similarity with the main magmatic mineral assemblage of damtjernites, suggesting a juvenile composition for them. The composition of phlogopite, carbonate and fluorapatite in pelletal lapilli is mostly constrained toward primitive compositions (beginning) of mineral crystallization trends in ultramafic lamprophyres. According to the petrographic and mineralogical features found in pelletal lapilli from damtjernites, these can be divided into three types based on the conditions and depth they were formed at. Estimated late magmatic temperatures of pelletal lapilli mica and fluorapatite formation vary from 815–990°C. The distinct composition and genesis of juvenile pelletal lapilli allows us to propose them as a new type of melt inclusions in ultramafic lamprophyres.
Prognosis prediction of patients with gastric cancer by a risk model based on immunogenic cell death-related genes
Authors: Wu Jianli , Li Le , Cheng Zhenyun 
Published: January 2023

Abstract
Immunogenic cell death (ICD) plays an important role in cancer. We aimed to classify patients with gastric cancer based on ICD gene-expression levels and construct a risk model to predict patient prognosis. A total of 33 ICD genes were obtained from a previously published study. Gene expression and clinical data of stomach adenocarcinoma (STAD) patients were downloaded from The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases. ConsensusClusterPlus analysis was used to cluster the patients based on ICD-gene expression. Kaplan–Meier curves were used to compare the prognosis of patients in different clusters. Differentially-expressed genes (DEGs) within the two ICD clusters were screened. LASSO and stepwise Cox regression analyses were performed to construct the prognosis-related risk model. Finally, a nomogram was constructed based on the independent factors. There was a difference in ICD gene-expression patterns between tumor and normal samples. Patients in the C1 cluster had a significantly better prognosis compared to those in the C2 cluster. Apolipoprotein D (APOD), collagen, type VIII, alpha 1 (COL8A1), collagen triple helix repeat containing 1 (CTHRC1), fibrillin 1 (FBN1), follistatin-related protein 1 (FSTL1), heat shock protein beta-8 (HSPB8), and secreted frizzled related protein 2 (SFRP2) genes were used to construct the risk model. Additionally, patients in the high-risk group had a significantly worse prognosis than those in the low-risk group. Age, stage, and risk groups were incorporated into the nomogram model. This nomogram showed great predictive value. Clusters of patients with gastric cancer based on ICD gene-expression levels had a predictive prognosis value. The risk score model constructed using APOD, COL8A1, CTHRC1, FBN1, FSTL1, HSPB8, and SFRP2 was an independent factor for poor prognosis in gastric cancer patients.
Similar growth responses to climatic variations in Norway spruce (Picea abies) and European beech (Fagus sylvatica) at the northern range limit of beech
Authors: Lie Marit H , Asplund Johan , Göhl Matthias , Ohlson Mikael , Nybakken Line 
Published: January 2023

Abstract
In south-east Norway, in the hemiboreal vegetation zone, the beech reaches its northern distribution limit and typically occupy the same type of sites as spruce. Under future climate change, this area is projected to fall within the temperate zone and beech to increase its distribution towards north at the expense of spruce. However, such forecasts are based on very broad scale estimates and the knowledge of climatic adaptation and the competitive potential of the beech and spruce populations at these latitudes is scarce. Here, we use a dendrochronological approach to study the growth performance of neighbouring spruce and beech trees to climate variability over a period of 70 years. The two species responded quite similarly to variation in climate in the study area. Both showed increased incremental growth in response to high precipitation both in previous and present year June, indicating that water is a limiting resource. In addition, beech showed a negative response to high temperatures in previous July and August, which is probably connected with growth reductions due to masting. Overall, spruce and beech in the hemiboreal zone show comparable responses to climatic variations as in the temperate zone. Due to the different drought-handling strategies of the two species, we suggest that the intensity of summer droughts and the variability between years are likely factors that would be decisive for which of them that will be more successful under future climatic conditions.
Importance of 24 Hours Ambulatory Blood Pressure Monitoring in Patients With Acromegaly and Correlation With Cardiac Magnetic Resonance Findings
Authors: Rocha Paula , Barroso Julia , Carlos Fernanda , Muxfeldt Elizabeth , Gadelha Monica , Kasuki Leandro 
Published: January 2023

Abstract
Arterial hypertension (AH) is prevalent in acromegaly, but few studies using 24-hour ambulatory blood pressure monitoring (24h-ABPM) suggest that its frequency may be different from office blood pressure (OBP). Left ventricular hypertrophy (LVH) is one of the most frequent cardiac abnormalities. Cardiac magnetic resonance (CMR) is considered the gold standard to evaluate the heart.
OBJECTIVES: To compare the frequency of AH when measured by 24h-ABPM and by OBP and to correlate BP with cardiac mass.
METHODS: Patients over 18 years of age with acromegaly underwent OBP evaluation and were later referred to the 24h-ABPM. Treatment-naïve patients were submitted to CMR.
RESULTS: We evaluated 96 patients. From 29 non hypertensive patients by OBP, 9 had AH on 24h-ABPM. In the group of patients with a previous diagnosis of AH by OBP, 25 had controlled BP and 42 had abnormal BP on 24h-ABPM when analyzed by OBP there were 28 with controlled BP. We observed a positive correlation between diastolic BP measured in 24h-ABPM and IGF-I levels, but we do not observe the same correlation with age, sex, body mass index and GH levels. The CMR was performed in 11 patients. We found a positive correlation of left ventricular mass (LVM) and BP of 24h-ABPM. In contrast, there was no correlation of OBP with CMR parameters.
CONCLUSIONS: We observed, that 24h-ABPM in acromegaly allows the diagnosis of AH in some patients with normal BP in OBP and also to allow a better treatment. 24h-ABPM shows a better correlation with VM by CMR.
We observed that 24h-ABPM in acromegaly is important because it allows the diagnosis of arterial hypertension in some patients with normal blood pressure in OBP and also to allow a better management of drug treatment in patients previously diagnosed with AH. Also, it shows a better correlation with ventricular mass when assessed by the gold-standard method CMR. Therefore, we think our study can contribute to the management of patients with acromegaly, highlighting the importance of using 24h-ABPM and not only OBP in these patients.
A low-rank update for relaxed Schur complementpreconditioners in fluid flow problems
Authors: Beddig Rebekka S. , Behrens Jörn , Borne Sabine Le 
Published: January 2023

Abstract
The simulation of fluid dynamic problems often involves solving large-scale saddle-point systems.Their numerical solution with iterative solvers requires efficient preconditioners. Low-rank updates canadapt standard preconditioners to accelerate their convergence. We consider a multiplicative low-rank cor-rection for pressure Schur complement preconditioners that is based on a (randomized) low-rank approxi-mation of the error between the identity and the preconditioned Schur complement. We further introducea relaxation parameter that scales the initial preconditioner. This parameter can improve the initial pre-conditioner as well as the update scheme. We provide an error analysis for the described update method.Numerical results for the linearized Navier-Stokes equations in a model for atmospheric dynamics on twodifferent geometries illustrate the action of the update scheme. We numerically analyze various parametersof the low-rank update with respect to their influence on convergence and computational time.
MSC codes. 65F08, 65F10, 65N22, 65F55
Evaluation of the Effectiveness of Different Treatment Approaches in Preventing Coronal Discoloration Caused By Regenerative Endodontic Treatment
Authors: Ateş Melis Oya , Aydın Z. Uğur 
Published: January 2023

Abstract
Objectives
This study aimed to evaluate the effectiveness of Teethmate desensitizer, a dentin bonding agent (DBA), Nd:YAG laser, and Er:YAG laser, which provides dentin tubule occlusion in the pulp chamber with different mechanisms, in preventing tooth discoloration due to regenerative endodontic treatment.
Materials and Methods
One hundred five extracted maxillary human incisors with single roots and single canals were included in the study. The apical third of each tooth was resected below the enamel-cementum junction (CEJ) to obtain a standard root length as 10 ± 1 mm. Root canal preparation was performed using the ProTaper Next files up to X5. Root canals were prepared with Gates Glidden (# 2–4) burs to simulate the immature root apex and an apical diameter of 1.1 ± 0.1 mm was obtained. The teeth were randomly divided into 7 groups (n = 15): DBA, Teethmate, Nd:YAG, Er:YAG, Biodentine, Blood, and Negative Control. Relevant dentin tubule occlusion methods were applied to DBA, Teethmate, Nd:YAG, and Er:YAG groups. Biodentine was placed on the blood clot after filling the root canals with blood up to 4 mm below the CEJ in all groups, except for blood and Biodentine applications only. Color measurement was performed with the spectrophotometer Vita Easyshade Advance before treatment, immediately after treatment, and at days 7, 30, and 90. Data were converted to L*a*b color values of Commission International de I'Eclairage (CIE L*a*b) and ΔE values were calculated. Two-way Anova and Post-Hoc Tukey test (p = 0.05) were performed for statistical analysis.
Results
A clinically detectable color change was observed in all groups except for the negative control (ΔE ≥ 3,3). It was observed that Biodentine used alone has a potential for discoloration. It was determined that as the contact time with blood increased, tooth discoloration increased. However, no significant difference was found between dentin tubule occlusion methods in preventing color change (p > 0.05).
Conclusions
It was determined that no dentin tubule occlusion method could 100% prevent discoloration caused by RET.
Clinical Relevance
DBA and Teethmate, which do not have a significant difference in terms of preventing color change, are considered to be suitable for dentin tubule occlusion due to their ease of application and low cost compared to Nd:YAG laser and Er:YAG laser.
A Context-Aware Personalized Recommendation System for Smart Home Automation based on Unsupervised and Supervised Learning Algorithms
Authors: Dilekh Tahar , Benharzallah Saber , Mokeddem Ayoub , Kerdoudi Saoueb 
Published: January 2023

Abstract
Current home automation systems allow remote monitoring and control of smart home devices. However, the problem caused by autonomous or self-controlled home automation is that predicting inhabitant behaviour and desires in every situation with 100% accuracy is unrealistic, at least for now. Therefore, the actual implementation of autonomous home automation may prove daunting and rigid for some users. Additionally, inhabitants want to be in control and want control over when and how things are done, this is due to their anxiety about losing control in favor of autonomous home automation. A personalized recommendation system for smart home residents with a certain degree of confidence is therefore ideal. This paper proposes a methodology to build a context-aware personalised recommender system for smart home automation. We suggest a predictive model for useful automation services of relevant smart home devices that smart home residents’ may wish to perform, by capturing the user’s current state and contextual preferences at that time. This is done by applying, in the first stage, an unsupervised algorithm to extract rules of behavior based on the resident’s previous interactions and passively captured in their daily lives by IoT-enabled sensors, and then, in the second stage, applying a supervised algorithm to recommend automation services in future instances when the actual behaviour of the user and context matches the established rules. Evaluations of smart home datasets show that the system produces correct recommendations with an average accuracy of 86.99%, a recall of 76.06%, and a precision of 82.67%.
Salvage McKeown esophagectomy for patients with squamous cell carcinoma of the thoracic esophagus with a history of total pharyngolaryngectomy and free jejunal graft reconstruction
Authors: Sugawara Kotaro , Fukuda Takashi , Kishimoto Yutaka , Oka Daiji , Shirakura Satoru , Kawashima Yoshiyuki 
Published: January 2023

Abstract
A 64-year-old man, who had previously undergone definitive chemoradiotherapy (dCRT) and endoscopic resections for metachronous multiple esophageal squamous cell carcinoma (ESCC) and had also received total pharyngolaryngectomy (TPL) for hypopharyngeal cancer, was diagnosed with ESCC in the middle thoracic esophagus (cT3N0M0). Salvage surgery was performed via thoracoscopy. Although the tumor was tightly adherent to the thoracic duct and both main bronchi, they were successfully mobilized. In order to maintain the blood supply to the trachea, we preserved the bilateral bronchial arteries and avoided prophylactic peritracheal lymph node dissection. Cervical end-to-side anastomosis between the jejunum and a gastric conduit was performed. Minor pneumothorax was managed conservatively, and the patient was discharged 44 days after the surgery. Overall, thoracoscopic salvage McKeown esophagectomy was safely performed in a patient with a history of TPL and dCRT. Surgeons should be very careful to prevent tracheobronchial ischemia by optimizing the extent of lymph node dissection.