bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of suicide prevention program for community dwelling elderly
Authors: Kim K. , Yoon B.-H. , Gwon H. , Park S. 
Published: August 2023

IntroductionThe suicide rate in the elderly population is the highest of all ages in Korea. Suicide prevention programs specialized in the elderly are scarce.ObjectivesWe evaluated the effect of the suicidal prevention program named “Nae-an-ae” (means to love oneself
), which was specifically designed for the conditions of the community dwelling elderly.MethodsThe subjects were those who agreed to participate in the Nae-an-ae program among those evaluated as suicide high-risk groups according to the 2021 Jeollanam-do Mental Health Survey. The program consisted of five sessions of simple activities that could be practiced in daily life along with knowledge transfer through education on emotion recognition, stress management, sleep and relaxation, pain and exercise, and depression. This program was conducted by social workers or nurses working at each local community mental health and welfare center. We evaluated the Geriatric Depression Scale-Short Form Korean Version (GDS-SF), suicidal ideation, satisfaction with life scale (SWLS) and brief resilience scale (BRS) which were measured before and after the program and compared them with the control group.ResultsA total of 276 participated in the program, 226 were in the control group. In the program participating group, the frequency of suicidal ideation was significantly decreased from 36.2% to 11.6% after the program. GDS-SF, SWLS and BRS were significantly decreased in active group than control group.Image:Image 2:Image 3:ConclusionsThese findings showed that “Nae-an-ae” program was found to affect not only the control of suicide risk factors such as depression but also positive factors such as life satisfaction and resilience.Disclosure of InterestNone Declared
Supervision as a tool of professional support of specialists
Authors: Dovbysh D. , Bebchuk M. 
Published: August 2023

IntroductionIn recent years, mental health professionals have faced a lot of difficulties and challenges in their work and often need the help of colleagues themselves.ObjectivesTo study the specifics of self-reflection of mental health professionals in different years (January 2020 - October 2022)MethodsSince 2002, Institute of Integrative Family Therapy has been using an approved registration card, which is filled in and handed over after completion of work by all specialists working with families. The maps contain sections describing the progress of work, hypotheses, system parameters of the family, features of the state of the specialist and clients, and so on. We conducted a content analysis of the cards: in 2020, 531 cards were considered, in 2021 - 390, in 2022 - 464 cards.ResultsThere are differences in the subjective assessment by specialists of their condition over the years. In the description for the section “Themes and questions in family work that elicited strong emotional reactions from the therapist(s”), professionals began to mention their reactions of fear and confusion more often than before. So, in 2020, fear was mentioned by 4 and confusion by 17 specialists, in 2021 - by 5 and 16, in 2022 - by 36 and 121, respectively. In the section related to the reasons for changing the working (systemic) hypothesis, specialists changed the hypothesis more often (in 2020 - in 53 cases, in 2021 - 40, in 2022 - 98). “The degree of satisfaction of the specialist (-s) with the results of working with the family (in points from 1 to 10, where 1 - absolutely not satisfied, 10 - satisfaction exceeded all expectations" was assessed in 2022 by specialists lower than in previous years: the average value in 2020 - 8.8; in 2021 - 8.9; in 2022 - 6.2.ConclusionsSupervision, as a form of professional growth and support from a more experienced colleague, is becoming an indispensable component of the work of a specialist helping families in 2022. Assistance in overcoming “dead end” and advising difficult cases due to the experience of the supervisor, on the one hand, allows specialists to understand the situation, offer alternative hypotheses, teach new interventions, on the other hand, it helps the supervised colleague to reflect on the case, analyze its “blind” zones, understand mistakes and summarize the unique experience gained in the psychotherapy of a “difficult” patient.Disclosure of InterestNone Declared
Substance Use Disorders and other Mental Health Disorders associated with sexualized intravenous sbustance use (slamsex)
Authors: Curto Ramos J. , Barrio P. , Ibarguchi L. , García A. , Garde J. , Oliva A. , Dolengevich Segal H. 
Published: August 2023

IntroductionThe intentional use of drugs before or during sexual intercourse (chemsex) is a phenomenon of special importance in the MSM (men who have sex with men) population due to its impact on mental, physical and sexual health.ObjectivesThe objective of this study was to compare the psychopathological characteristics between users whith sexualized intravenous substance use (slamsex) versus those who did not slamsex attended by the non-govenrmental organization Apoyo Positivo in the program “Sex, Drugs and You”.MethodsA cross-sectional descriptive analysis of a sample of users attended by the non-govenrmental organization Apoyo Positivo in the program “Sex, Drugs and You” was performed.Results230 participants were included. Slam was associated with higher risk of having and anxiety or depressive disorder, suicidal ideation, induced psychosis and suicidal behavior, the differences were statistically significant (p<0.05) in all cases.ConclusionsSlamsex is usually reported in our sample. Substance use disorders in slam users are usually associated with other mental disorders. This challenge requires adapt the therapeutical interventions of the professionals who work with patients with chemsex practices, specially with those who practice slamsex.Disclosure of InterestNone Declared
Sex-specific associations of different risk behaviors with socio-demographic, health status and lifestyle factors
Authors: Kose J. , Duquenne P. , Hercberg S. , Galan P. , Touvier M. , Fezeu L. K. , Valentina A. A. 
Published: August 2023

IntroductionKnowledge about concurrent substance use and other risk behaviors - as well as their determinants - in the general population is insufficient.ObjectivesTo investigated socio-demographic, health status, and lifestyle determinants of habit-forming risk behaviors among French men and women.MethodsWe analyzed data collected in 2021–2022 from 32,622 participants (74.5% female; mean age=57.9±14.2 years) of the NutriNet-Santé web-cohort who had completed the Alcohol Use Disorders Identification Test, the 12-item Cigarette Dependence Scale, the modified Yale Food Addiction Scale 2.0, and the Internet Addiction Test. Using established cutoff values, participants were first split into 2 groups (Yes/No) for each risk behavior (alcohol use disorders, nicotine dependence, food addiction, and Internet addiction) and then placed into 3 groups (no risk behavior, 1 risk behavior (reference), and ≥2 risk behaviors) before fitting polytomous logistic regression models according to sex.ResultsYounger age (Odds Ratio: ORmale=2.07; ORfemale=2.04), self-perceived poor health (ORmale=2.06; ORfemale=1.61), having obesity (OR=1.56; ORfemale=1.30), lack of affection during childhood (ORmale=1.56; ORfemale=1.39), and a lifetime prevalence or medication use for a mental disorder (ORmale=1.73; ORfemale=1.38) were significantly associated with having ≥2 versus 1 habit-forming risk behavior in both sexes (all p<0.05). Results for experiencing current financial difficulties (ORfemale=1.34), self-perceived poor dietary quality (ORfemale=3.23), being underweight (ORfemale=1.58) and overweight (ORfemale=1.30) were significant only in females (all p<0.05). The same factors plus current e-cigarette use (ORmale=0.54; ORfemale=0.77) in both sexes, having a higher educational attainment (ORfemale=0.75), being physically active at work (ORfemale=0.78) in females were inversely associated with having none versus 1 risk behavior (all p<0.05).ConclusionsTo our knowledge, this is the first study to explore determinants of concurrent habit-forming risk behaviors among men and women in a large, population-based study. The findings could serve as impetus for future research in this domain and ultimately help guide addiction prevention efforts.Disclosure of InterestNone Declared
Clinical and biological features associated to bipolar disorder with comorbid migraine: results from the FACE-BD cohort
Authors: Patoz M.-C. , Godin O. , Moisset X. , Chabert J. , M’Bailara K. , Etain B. , Belzeaux R. , Dubertret C. , Haffen E. , Schwan R. , Roux P. , Polosan M. , Aubin V. , Leboyer M. , Courtet P. , Olie E. , Llorca P.-M. , Samalin L. 
Published: August 2023

IntroductionMigraine and bipolar disorder (BD) are two chronic and recurrent disorders with a major impact on patient’s quality of life. It is now well known that affective disorders and migraine are often comorbid (Leo et al. Scand J Pain. 2016; 11:136-145). Starting from these observations, we can hypothesis that BD patients with comorbid migraine might have specifical clinical and biological features.ObjectivesThe aim of this study was to estimate the prevalence of migraine in a cohort of French BD patients; determine sociodemographic, clinical, and biological features associated BD-migraine comorbidity.Methods4348 BD patients from the FACE-BD cohort were included from 2009 to 2022. Sociodemographic and clinical characteristics, lifestyle information, and data on antipsychotic treatment and comorbidities were collected, and a blood sample was drawn. The Structured Clinical Interview for DSM-IV Axis I Disorders was used to confirm the diagnosis of BD. Migraine diagnosis was established according to a clinician-assessed questionnaire.Results20.1% of individuals with BD had comorbid migraine. Half of these patients received treatment for migraine. Multivariate logistic regression model showed that risk of migraine in women was nearly twice that in men (OR = 1.758; 95% CI, 1.345-2.298). Anxiety disorder, sleep disturbances and childhood trauma were also associated with an increased risk of migraine comorbidity. Patients receiving antipsychotic treatment had less risk of developing migraine than those not receiving those treatment (OR 0.716, 95% CI, 0.554-0.925), independent of other potential confounders.ConclusionsThe prevalence of migraine in our cohort was lower than those previously reported in other studies. This result might suggest an overestimation of migraine diagnosis in BD patients population studies. However, BD-migraine comorbidity could constitute a subphenotype of bipolar disorder requiring specific treatments.Disclosure of InterestNone Declared
Fecal Short-Chain Fatty Acids as Potential Biomarkers for Attention-Deficit/Hyperactivity Disorder
Authors: Boonchooduang N. , Louthrenoo O. , Likhitweerawong N. , Thonusin C. , Chattipakorn N. , Chattipakorn S. C. 
Published: August 2023

IntroductionGrowing evidence supports a possible link between gut microbiota and attention-deficit/hyperactivity disorder (ADHD) via the gut-brain axis. Short-chain fatty acids (SCFAs), the major metabolites produced by gut microbiota through anaerobic fermentation, may influence gut-brain communication.ObjectivesTo determine the alterations of gut microbiota and fecal SCFAs in children diagnosed with ADHD compared to healthy subjects.MethodsFecal samples were collected from children with ADHD (n=10), and age- and sex-matched healthy controls (n=10) for gut microbiota and SCFAs analysis.ResultsThere were no significant differences in the abundance of any bacterial phyla in feces between groups. However, fecal concentrations of acetic acid, propionic acid, and butyric acid were significantly lower in children with ADHD compared to those of controls (Figure1). Interestingly, acetic acid and propionic acid levels were negatively correlated with ADHD symptoms (
Table 1). Macronutrient and fiber intake, determined from food frequency questionnaires, did not differ between groups.Table 1.The regression analyses predicting ADHD symptoms scores from fecal short-chain fatty acids level.Bp-value95%CIInattention scoreAcetic acid-0.140.009-0.24, -0.04Propionic acid-0.180.006-0.30, -0.06Hyperactive/Impulsive scoreAcetic acid-0.100.031-0.20, -0.01Propionic acid-0.140.018-0.25, -0.03Combined scoreAcetic acid-0.120.014-0.22, -0.03Propionic acid-0.160.008-0.27, -0.05Image:ConclusionsOur findings suggested that gut dysbiosis was possibly developed in children with ADHD, as indicated by a significant decrease in fecal SCFAs. In fact, fecal acetic acid, propionic acid, and butyric acid may potentially be the early detector for ADHD. In addition, fecal acetic acid and propionic acid could be potential biomarkers for the severity of ADHD.Disclosure of InterestNone Declared
Cognitive characteristics in women with mastectomy, mental symptoms and marriage compliance
Authors: Gürcen H. B. , Karaca S. 
Published: August 2023

IntroductionAlthough mastectomy is a treatment for the cleaning of cancer cells in the breast, it can also cause psychological changes in women.ObjectivesThis research was carried out to investigate the cognitive distortions, mental symptoms, and marital adjustment relationships in women with mastectomy.MethodsThe descriptive and comparatice study was conducted in a public hospital with 90 mastectomies and 90 healthy female samples. The data were collected using The Cognitive Distortions Scale (CDS), The Brief Symptom Inventory (BSI), and Marriage Adjustment Scale (MAS) and were evaluated by descriptive statistical analyzes, t test, Mann-Whitney U test and Spearman Correlation Analysis.ResultsWomen with mastectomy scored high in the healthy control group in all sub-dimensions of CDS and BSI and this difference is highly significant (p<0,5). Women with mastectomy scored higher in total agreement sub-dimensions than the healthy control group and the difference between them was statistically significant (p<0,5). There ara positive, very strong and statistically significant relationships between all sub-dimensions of the CDS and the total sub-dimension scores of the BSI (r=,769and, 919). There are positive, strong and statistically significant relationships between the sub-dimensions of the CDS and the sub-dimension of the agreement and the total score of MAS (r=681 and 734). There are strong and statistically significant relationships between the total and sub-dimension scores of the BSI and the sub-dimension and total score of the MAS’s agreement (r=,672 and 778).ConclusionsCognitive distortions and mental symptoms are significantly higher in women with mastectomy, and cognitive distortions are associated with mental symptoms. Cognitive distortions and psychological symptoms scores, marriage adjustment scores and agreement sub-dimension scores increase in women.Disclosure of InterestNone Declared
Descriptive analysis of unfavorable mental health opinions of candidates for bariatric surgery
Authors: Pereira R. C. , Delgado A. , Ferreira F. M. 
Published: August 2023

IntroductionIn recent years, there has been an increase in the number of candidates for bariatric surgery and a decrease in psychiatric contraindications.ObjectivesWe aim to make an descriptive evaluation of unfavorable feedback concerning mental health of the candidates for bariatric surgery of the Local Health Unit of Matosinhos (Porto, Portugal).MethodsDescriptive analysis of unfavorable feedback of mental health of candidates for surgical treatment of obesity.ResultsFrom March 2017 to August 2022, the Mental Health Service of the Local Health Unit of Matosinhos issued 347 pre-surgical feedback. In 63 cases the initial opinion issued was unfavorable: 11 cases due to a psychiatric contraindication (not meeting conditions for intervention) and 52 cases had a conditional opinion (requiring pre-surgical interventions in order to become eligible for the intervention). Regarding contraindications, these were due to alcohol use disorder (n=3), binge eating (n=3), intellectual development disorder (n=2), purgative behavior (n=1), psychotic disorder (n=1) and mood disturbance (n=1). In terms of conditional opinions, the issues mencioned were lack of motivation for surgery (n=22), psychopathology (n=20), doubts about informed consent (n=8) and need for multidisciplinary discussion/coordination (n= 7).ConclusionsThere was an increase in eligibility of candidates for surgical treatment as most of the initial unfavorable opinions were conditional. This could be explained by the decline of complications associated with bariatric surgery, but also because psychiatric disorders are now being viewed as treatable. Notably people with eating disorders are now fit for surgery after a medical or psychotherapeutic intervention.Disclosure of InterestNone Declared
Effect of antidepressant therapy on the severity of COVID 19 symptomatology in the hospitalized patients
Authors: Spirkoska L. , Spasovska Trajkovska A. , Mitik Z. 
Published: August 2023

IntroductionSome studies reported that vaccines are extremely good at preventing serious illness but that many countries have had difficulty vaccinating their citizens, and even some vaccinated people may still be at risk for serious COVID-19 symptoms due to underlying medical illness or reduced immunity over time.ObjectivesSome researches reported that drugs known as selective serotonin-reuptake inhibitors (SSRIs) interacts strongly with the sigma-1 receptor, a protein inside cells that helps regulate the body’s inflammatory response. So its believe that this drug most likely is interacting with the sigma-1 receptor to reduce the production of inflammatory molecules in the body, So treatment with this therapy may be highly effective to reducing severe of COVID symptomatology.MethodsThe cross-section study included two groups of patients (N = 30) of different sex ±49,2 age, all were treated in Covid Centre , Skopje. The study was conducted for 6 months all the patients was writing informed consent. The first group consisted of COVID patients who had previously suffered from psychiatric illness and had been treated with antidepressant therapy (SSRi). The second group are the COVID patients who had not been treated with antidepressant before. The severity of COVID 19 symptomatology (based on medical documentation- classification of disease severity) was determined using the Modified Early Warning Score (MEWS scale) . MEWS score 0-2 mild or asymptomatic (stable patients), 3-4 moderately severe (unstable patients), ≥ 5 highly critical(critical patients). The obtained data were processed by descriptive method and Student t-test.Results. The results in our study show that the patients who were treated with antidepressants before covid disease showed a lower score on the NEWS scale but there is a not statistically significant results p=0,06 when compare with another examination groupConclusions: The results in our study supports considerations about the possible impact of antidepressant therapy on alleviating COVID 19 symptomatology.Disclosure of InterestNone Declared
Social connection and depression: an umbrella review of meta-analyses assessing the magnitude of risk and protection
Authors: Pettorruso M. , Collevecchio R. , Zoratto F. , Collacchi B. , Boffa M. , Santorelli M. , Clerici M. , Martinotti G. , Borgi M. 
Published: August 2023

IntroductionDepression is a severe mental disorder with an estimated 3.8% of the population affected, representing a leading cause of disability worldwide. Being linked to reduced quality of life and individual functioning, medical morbidity and mortality, depression has a huge social and economic impact. A wide range of potentially modifiable factors for depression has been identified. Among these, social factors (e.g. support/engagement) appear to play a major role in the emergence and severity of depression.ObjectivesWe aimed at providing a quantitative synthesis of the consistency and magnitude of the association between measures of social connection and depression. Social connection included both quantitative (i.e. existence/absence of social relationships) and functional (i.e. support provided) measures of social relationships, as well as measures focusing on social inequalities related to participation in community spaces/activities (i.e. social discrimination).MethodsWe searched PubMed, PsycINFO, Cochrane Library and EMBASE. The strength of the association between exposure factors (social measures) and depression was extracted and equivalent odds ratios were computed to compare the strength of the effect sizes among meta-analyses. The quality of each review was assessed using AMSTAR-2.ResultsAs a result of the selection process 47 studies were included in the umbrella review. Social support was found to have a protective role on depression, with an observed moderate/strong effect in peripartum population and a weaker effect in clinical populations (e.g. AIDS/HIV patients). A moderate association between stigma/discrimination and depression emerged in clinical populations (e.g. epilepsy, mental illness, post-stroke), while a weaker effect was found in (ethnic) minorities. There are still few studies quantitatively investigating the link between depression and other social measures (e.g. community connectedness).ConclusionsOur findings align with the literature on social connection and mental health, confirming the role of social determinants in the emergence and severity of depression, particularly in the case of vulnerable populations. Social factors emerge as important modifiable targets in the context of depression prevention. Efforts to counteract disconnection at the societal and individual levels and to reduce stigma should be central to an effective depression prevention agenda.Disclosure of InterestNone Declared