bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of Pt/CNT Catalyst with High Dispersion Structure via Plasma Jet
Authors: Li Shaolong , Gao Fanchuan , chang qiang , Guo Ruiyu , Guo Jiaru , Wang Yixuan , Wu Jingyu , Zhang Ye 
Published: March 2023

Abstract
A plasma jet method based on free arc was carried out to disperse carbon nanotubes (CNTs) in gas phase and produce Pt nanoparticles (Pt-NPs) on them at the same time. The plasma jet is generated through the discharge between the cathode composed of CNTs, PtCl4 and ID water and the anode with a hole. Plasma jet prepares the Pt/CNT catalyst by directly spraying. The CNT carrier in the catalyst have good dispersion by SEM images. The mean size of Pt-NPs estimated by TEM images is 3.41nm with the plasma jet method and about 4.77nm with the commercial Pt/C respectively. It was showed that the bulk of Pt-NPs produced by plasma jet is in metal state in the analysis of XPS measurements. Compared with Pt/C, Pt/CNT have roughly equal catalytic activity and higher durability by cyclic voltammetry measurements. On the basis of these properties, the plasma jet method greatly simplifies the preparation process of the catalyst by simultaneously solving carrier dispersion and metal particle preparation.
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: A retrospective study combined with external validation
Authors: Liu Shuang , Lv Dongmei , Zhao Yixuan 
Published: March 2023

Abstract
Background: Treatment options for T1/2N0M0 anal squamous cell carcinoma include chemotherapy, radiotherapy, chemoradiotherapy, and local excision, although the optimal treatment method has not been determined.
Methods: The National Cancer Institute Surveillance, Epidemiology and Results database was used to search and screen 1,465 patients with cT1/2N0M0 anal squamous cell carcinoma who were clinically diagnosed between 2004 and 2016. Survival analysis was performed using the Kaplan-Meier method and log-rank test. Cox proportional hazards regression analysis was performed to screen independent prognostic factors and build a nomogram survival prediction model. According to the risk score, patients were divided into low, medium, and high risk groups using X-tile software.
Results: Age, sex, grade, size, and cT stage were identified as independent prognostic factors for cT1/2N0M0 anal squamous cell carcinoma and were included in the nomogram to construct a prediction model. The C-index of the model was 0.670 [95% confidence interval (CI), 0.693–0.756], which was higher than the C-index of T stage 0.565 (95% CI, 0.550–0.612). Low risk patients benefited from local resection, medium risk patients benefited from radiotherapy, and high risk patients benefited from radiotherapy or chemoradiotherapy. This was confirmed using external validation data from the center.
Conclusion: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for intermediate risk patients, and radiotherapy or chemoradiotherapy for high risk patients.
Inflammation Induces Endoplasmic Reticulum Stress and Its Pro-apoptotic Effect is Attenuated by Hexokinase 2-mediated Glycolysis in Lymphatic Endothelial Cells: A Potential Role in Lymphatic Malformations
Authors: Li Xuecong , Jiang Hao , Chai Maosheng , Zhu Tianshuang , Liu Jingjing , Huang Congfa , Yang Shaodong , Mou Dongsheng , Zhou Xiaoshun , Zhong Wenqun , Cai Yu 
Published: March 2023

Abstract
Lymphatic malformations(LMs) are a kind of developmental disease most occurring in the head and neck with different symptoms. Clinical experiences showed that the lesion will grow rapidly after infection. Previous studies have shown that inflammation can cause endoplasmic reticulum stress (ER Stress) in many cell lines and would affect the progression of the disease. In this study, we explored the contribution of ER Stress and ER stress-related apoptosis in LMs. Our in vivo and in vitro models showed inflammation could induce the activation of aerobic glycolysis and ER stress, while glycolysis could rescue ER stress-mediated apoptosis in human dermal lymphatic endothelial cells, which is required for the accelerated development of LMs. Besides, our study showed that compared to normal skins, glucose-regulated protein 78 (GRP78/BIP), a key ER stress-associated protein, was up-regulated in lymphatic endothelial cells of LMs, which was closely correlated with the inflected state. In addition, excessively activated ER stress inhibited the progression of LMs in rat models, which implies a promising target for the treatment of LMs.
Analysis on the Evolution of the Green Infrastructure Network Pattern of the Hanjiang Ecological Economic Zone in China
Authors: He Pengfei , Chen Kunlun 
Published: March 2023

Abstract
Context Green Infrastructure (GI) can provide multifunctional ecosystem services to cities and their inhabitants. Among them, it has become a new field to study GI planning from the perspective of landscape ecology.
Objectives To reveal the spatial and temporal evolution characteristics of GI network in the Hanjiang Ecological Economic Zone from 2010 to 2020. it provides an important basis for regional GI planning.
Methods adopting the methods of morphological spatial pattern analysis (MSPA), landscape index, minimum cumulative resistance model (MCR) and network analysis to construct and evaluate the GI network.
Results The area of GI landscape continued to grow, and the Core was the most important landscape category which was densely distributed in the upper reach. the GI connectivity firstly decreased and then increased, which was consistent with results of patch density and contagion index. The comprehensive resistance value decreased from northwest to southeast, but high-resistance area showed a continuous trend of expansion. The α, β and γ values of GI network has decreased first and then increased, which is consistent with the change of the number of GI sources.
Conclusions The GI landscape around city was severely affected by urban expansion. Its area was continually shrinking and structure tended to be simplified. Thereby, there was great challenge to protect and restore it. The network structure presented a pattern of “local connectivity and overall looseness”, which greatly limited the scope of species dispersion and energy flow. The number and area of GI sources were the key to network structure optimization.
Predicting emerging zoonotic disease under resource-limited settings: Case study of Kyasanur Forest Disease using event-based surveillance data and transfer learning
Authors: Keshavamurthy Ravikiran , Charles Lauren E. 
Published: March 2023

Abstract
In recent years, the reports of Kyasanur Forest Disease (KFD) breaking endemic barriers by spreading to new regions and crossing state boundaries is alarming. Effective disease surveillance and reporting systems are lacking for this emerging zoonosis, hence hindering control and prevention efforts. We compared time-series models using weather data with and without Event-Based Surveillance (EBS) information, i.e., news media reports and internet search trends, to predict monthly KFD cases in humans. We fitted Extreme Gradient Boosting (XGB) and Long Short Memory Chain (LSTM) models at the national and regional levels. We utilized the rich epidemiological data from endemic regions by applying Transfer Learning (TL) techniques to predict KFD cases in new outbreak regions where disease surveillance information was scarce. Overall, the inclusion of EBS data, in addition to the weather data, substantially increased the prediction performance across all models. The XGB method produced the best predictions at the national and regional levels. The TL techniques outperformed baseline models in predicting KFD in new outbreak regions. Novel sources of data and advanced machine-learning approaches, e.g., EBS and TL, show great potential towards increasing disease prediction capabilities in data-scarce scenarios and/or resource-limited settings, for better-informed decisions in the face of emerging zoonotic threats.
The effect of hold-melt time of micro-regime precipitation size and hardness in Al-Cu alloy
Authors: Suprapto Wahyono , Irawan Yudy Surya , Suparman Sudjito , Amrullah Muhammad Rafi , Auliasyah Pratama , Ramdhani Aditya Rafi 
Published: March 2023

This study aims to control the characterization and mechanical properties of smelting Al-Cu Alloy through Hold-Melt Time. This research uses aluminum scrap and copper wire scrap to produce quality as-cast ingots, clean the environment, and increase waste utilization. Copper melting point of 1083 °C is immersed in molten aluminum at a temperature of 900 °C for 10–30 minutes causing copper to dissolve in aluminum due to smelting events based on diffusion phenomena. Parameters of temperature and immersion time of copper in molten aluminum in this study are expressed by hold-melt time. In the copper aluminum alloy trade, commonly called Duralumin, it is commonly used for impact loads and is heat-treatable. Resistance to cryogenic temperatures, in the future Duralumin has the potential to replace stainless steel. This study used an electric resistance furnace with the specifications for smelting aluminum 3 kg, electric power 2.5–3.0 kW, electric voltage 220 Volts, maximum temperature 1000 °C. It had been conducted an experiment where copper had been melted under its melting point in duralumin ingot casting. In this study, copper pieces were soaked in liquid aluminum with temperature of 900 °C. After 10–30 minutes of holding melt, the soaked copper became Al-Cu alloys and was called molten Duralumin. After the molten duralumin had been cleaned from dross, it was poured into ingot casting. From specific weight test, more soaking time of the copper in liquid aluminum caused specific weight of ingot duralumin increase from 47.08 % to 57.56 % and its hardness increase from 93 to 113 BHN. This study contributes on melting energy saving and improves the characteristic and hardness of ingot aluminum type 2xxx
Баруун бүсийн зарим аймгуудын усыг борфа-аар судалсан нь
Authors: Ж Баярмаа , Ш Гэрбиш , Б Далхсүрэн , Ц Цэрэнгомбо 
Published: March 2023

Нами было определено содержание некоторых макро и микроэлементов в пробах воды, взятых из более чем 15 рек, озер и колодец находящихся на территории.Западной части Монголии. Макро и микроэлементы исследовались с применением спектрометра РФА с полным внутренним отражением в Центрө ядерных исследований Монгольского Госуниверситета. Концентрация элементоп в исследованных вод сильно различаөтся и поэтому недостаток или их избыток в той или иной степени влияет на живые организмы и может стать причиной их заболеваний.
К вопросу изучения динамики влажности почвы
Authors: Д Аззаяа , Э Эрдэнэбат 
Published: March 2023

Природно-климатические условия Монголии отличаются исключительно специфическими чертами и климат её характеризуется резкой континентальностью. Это обстоятельство обуславливает сильной степени зависимости возделывания сельскохоэяйственных культур и произрастания пастбищной растительности от природно-климатических условий. Водный режим сельскохозяйственных угодий, закономерности его иэменений в зависимости от погоды и агротехники-важная особенность местных условий, без учёта которой невозможно научно обоснованное ведение хозяйства.
A Comparative Analysis on the Model Adequacy of Four Transformation Techniques
Authors:   Department of Mathematics and Statistics University of Port Harcourt Choba, Port Harcourt, Nigeria Email: juanohugo@gmail.com, Anosike Joseph Ugonna ,   uchenna.ogoke@uniport.edu.ng, Ogoke Uchenna Petronilla 
Published: March 2023

ABSTRACT	This study compared four different transformation techniques by applying a simple linear regression on raw and transformed data. The R2 of each model was obtained and a test on the significance of these R2 was carried out. Also, the rxy(coefficient of correlation) were also obtained. The data used is a secondary data consisting of 53years (1964-2016) of the infant mortality rate in Nigeria (https://www.ceicdata.com/en/nigeria/health-statistics/ng-mortality-rate-infant-per-1000-live-births). The rxy were also compared and the results, 95.8%, 95.8%, 96.2%, 93.0%, and 92.9% respectively. The R2 obtained for the raw data, logarithm, square-root, square and inverse are as follows: 91.8%, 91.7%, 92.5%, 86.6% and 86.4% respectively. However, the R2 obtained for the raw data, logarithm, square-root, square and inverse compete favourably but the performance of inverse transformation suits the data most in terms of model accuracy. Key Words: Transformation, Raw data, logarithm, square-root, square, inverse
Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults: A Population-Based Cohort Study in Toronto, Canada
Authors: den Braver Nicolette R. , Beulens Joline W.J. , Wu C. Fangyun , Fazli Ghazal S. , Gozdyra Peter , Howell Nicholas A. , Lakerveld Jeroen , Moin John S. , Rutters Femke , Brug Johannes , Moineddin Rahim , Booth Gillian L. 
Published: March 2023

OBJECTIVECar dependency contributes to physical inactivity and, consequently, may increase the likelihood of diabetes. We investigated whether neighborhoods that are highly conducive to driving confer a greater risk of developing diabetes and, if so, whether this differs by age.RESEARCH DESIGN AND METHODSWe used administrative health care data to identify all working-age Canadian adults (20–64 years) who were living in Toronto on 1 April 2011 without diabetes (type 1 or 2). Neighborhood drivability scores were assigned using a novel, validated index that predicts driving patterns based on built environment features divided into quintiles. Cox regression was used to examine the association between neighborhood drivability and 7-year risk of diabetes onset, overall and by age-group, adjusting for baseline characteristics and comorbidities.RESULTSOverall, there were 1,473,994 adults in the cohort (mean age 40.9 ± 12.2 years), among whom 77,835 developed diabetes during follow-up. Those living in the most drivable neighborhoods (quintile 5) had a 41% higher risk of developing diabetes compared with those in the least drivable neighborhoods (adjusted hazard ratio 1.41, 95% CI 1.37–1.44), with the strongest associations in younger adults aged 20–34 years (1.57, 95% CI 1.47–1.68, P &lt; 0.001 for interaction). The same comparison in older adults (55–64 years) yielded smaller differences (1.31, 95% CI 1.26–1.36). Associations appeared to be strongest in middle-income neighborhoods for younger residents (middle income 1.96, 95% CI 1.64–2.33) and older residents (1.46, 95% CI 1.32–1.62).CONCLUSIONSHigh neighborhood drivability is a risk factor for diabetes, particularly in younger adults. This finding has important implications for future urban design policies.
Relationship of SNPs (rs3212227) in IL-12 with Gynecological and Breast Cancer*
Authors: Jebur Mays Hadi , AL-Shibly Ifad K. , Alrubaye Bushra J. 
Published: March 2023

Cancer refers to any disease among a large number of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to infiltrate and destroy normal body tissues. Cancer often has the ability to spread throughout the body. Cancer is the second leading cause of death in the world
Cancers can occur in any part of the female reproductive system — the vulva, vagina, cervix, uterus, fallopian tubes, or ovaries. These cancers are called gynecologic cancers.
Gynecological cancers can invade directly nearby tissues and organs, or spread (metastasize) through the lymph vessels, lymph nodes (lymph system), or the bloodstream to distant parts of the body.Breast cancer occurs when some breast cells begin to grow in an abnormal way. These cells divide more rapidly than healthy cells and continue to accumulate, forming a lump or tumor. The cells may spread (metastasize) through the breast to the lymph nodes or to other parts of the body.
Interleukin-12 (IL-12) is an anti-inflammatory cytokine that links innate and adaptive immune responses against cancer cells. Single nucleotide polymorphisms (SNPs) in the IL-12 genes have been associated with cancer risk. The role of IL-12 in breast cancer and gynecological risk overall, association of the IL-12 signaling pathway and BC risk in women.
In Vitro Study of Ag2O, MgO Nanoparticles and Sb Drug Cytotoxic Effects on Leishmania donovani
Authors: Esmail Hawraa H. 
Published: March 2023

Background: Leishmania is a parasitic protozoan that causes severe illness in humans. While pentavalent antimony compounds (Sb Drug) are used as antileishmanic drugs but are linked to limitations and many adverse complications.
Objective: Therefore, commitment is still needed to find a new and successful treatment.
Material & methods: In this study, the effect of Ag2O, MgO nanoparticles with mean particles size of (12-28)nm and(7-12)nm respectively on Leishmania was evaluated. Viability percentage of promastigotes following the addition of different concentrations of Ag2O, MgO nanoparticles and Sb drugs (25, 50, 100, 200 and 300 μg / ml ) to the parasite culture, assessed using colorimetric ALAMAR stain in (24,48 72)hours.
Results: The concentration that the number of parasite by half (IC50) value was measured after 24, 48 and 72 hours for Sb, Ag2O NPs and MgO NPs. For Ag2O NPs the IC50 was 2.404 after 72 hours only, and doesn’t reveal any value in 24 hour, 48 hour, in comparison to Sb drug and MgO NPs which doesn't reveal IC50 value in all used concentration and periods.
Conclusion: Our data determine the superiority of Ag2O NPs and MgO NPs over standard in vitro pentostam that's it. Provides the possibility of using these Ag2O NPs and MgO NPs as a drug target for candidates with better antileishmanial efficacy.
The checklist of Impatiens Riv. ex L. (Balsaminaceae) in Nilgiri and Palani Hills of southern Western Ghats (India)
Authors: S Jeevith  , Arigela Ravi Kiran , Rajeev Kumar Singh  , K Althaf Ahamed Kabeer  , C Rajasekar  , C Kunhikannan  
Published: March 2023

A comprehensive checklist of the genus Impatiens Riv. ex L. (Balsaminaceae) in Nilgiri and Palani of southern Western Ghats, India is presented. After thorough field explorations in these areas from 2012 to 2020 in different seasons, 38 species of Impatiens are recorded, in which 6 species are endemic to Western Ghats and 26 species are endemic to southern Western Ghats of India. Horticultural potential of 18 endemic species of balsam is also discussed.
Human Capital in the Context of the Principle of Diminishing Marginal Returns
Authors: Mayilyan F. N. 
Published: March 2023

The article examines the historical prerequisites for the emergence of the concept of the principle of diminishing returns of production factors. The analysis of the manifestation of this principle in the context of all factors of production. As a result of the analysis of the characteristics of human capital, an approach is proposed according to which the principle of diminishing marginal return does not apply to investments in human capital at the macrolevel and in the long term. It is shown that human capital at the macro level and in the long term (in the context of long waves of economic cycles) shows a trend of increasing returns. And it is the increasing return on investment in human capital that prevents the manifestation of diminishing returns on other factors of production. The reasons that determine the increasing return of human capital, as opposed to the physical, are systematized, among which: it, during a certain period of the process of use, improves, grows in quality and accumulates; does not disappear without a trace, contributes to the growth of human capital of other individuals, investments in human capital provide positive externalities, the component of human capital is a resource of knowledge, is inexhaustible and shows an exponential growth trend, the process of investing in human capital is greatly influenced by national, historical, psychological and socio cultural factors, investment in human capital, as a rule, provide a high rate of return.
Music of the 21st century: first results
Authors: Амрахова А.А. , Акопян Л.О. , Савенко С.И. , Селимханов Д. , Цареградская Т.В. 
Published: March 2023

Темой круглого стола стала музыка первых 18 лет XXI столетия. Обсуждению подверглись основные направления современного искусства — авангард, постмодернизм, а также особенности нового мироощущения, выразившиеся в сфере пространственно-временной организации и принципов формообразования музыкальных сочинений.
The theme of the round table focused on the music of the first 18 years of the 21st century. The main directions of contemporary art — avant-garde, postmodernism, as well as the features of the new worldview, expressed in the sphere of space-time organization and principles of form- building of musical compositions, were discussed.
The unknown opera by Edison Denisov
Authors: Григорьева Г.В. 
Published: March 2023

Статья посвящена юношеской опере Эдисона Денисова, ранее неизвестной. Премьера состоялась в 2016 году, для исполнения опера была оркестрована Юрием Каспаровым и поставлена в Томске, на родине композитора. В статье кратко описаны жанр оперы, стилистические истоки, структура, особенности драматургии. Опера рассматривается в связи с традициями русской классической оперы, а также в контексте неофольклоризма — яркого направления отечественной музыки 1950 – 1960-х годов.
The article focuses on the previously unknown оpera by young Edison Denisov. It premiered in 2016, the opera being orchestrated by Yury Kasparov and staged in Tomsk, the composer’s hometown. The article briefly describes the genre of the opera, its stylistic origins, structure, specific features of dramaturgy. The opera is regarded as having ties with the traditions of the Russian classical opera, as well as viewed within the framework of neofolklorism — a powerful artistic movement in the Russian music of the 1950s and 1960s.
Pengembangan dan Pendampingan UMKM Dompet Kulit Melalui Digitalisasi Marketing Berbasis Marketplace Shopee Untuk Menunjang Pemasaran dan Peningkatan Penjualan
Authors: Wusqo Any Urwatul , Fridayanti Biby Eka , Aisyah Siti 
Published: March 2023

UMKM dompet kulit di desa Pucangsari adalah salah satu UMKM pengrajin kulit berpotensi di Kabupaten Pasuruan. UMKM ini telah menggunakan marketplace Shopee sebagai media pemasaran, namun kurangnya pengetahuan dan kemampuan UMKM dalam mengelola marketplace Shopee tersebut membuat pemasaran digital belum berjalan maksimal. Marketplace yang sudah ada belum terkelola dengan baik. Sehingga pemasaran yang dilakukan belum mampu meningkatkan penjualan. Tujuan program pengabdian masyarakat ini selain untuk mengembangkan market place UMKM tersebut, yaitu juga bertujuan untuk pendampingan pengelolaan market place dalam jangka panjang. Metode yang digunakan dalam program pendampingan ini adalah metode PAR. Beberapa kegiatan program pengembangan dan pendampingan ini terdiri darikomunikasi dan koordinasi hingga proses problem solving, dimana kegiatan-kegiatan yang dilakukan terfokus pada pemaksimalan marketplace shoppe milik UMKM dompet kulit. Pengembangan dan pendampingan market place ini akan berpengaruh besar terhadap peningkatan penjualan dan perluasan pemasaran. Selain itu optimalisasi market place dapat menciptakan keunggulan bersaing ditengah pandemi Covid. Harapan adanya pendampingan ini UMKM dapat menambah wawasan mengenai pengelolaan Marketplace Shopee dengan baik. Dengan adanya program pengembangan dan pendampingan ini, UMKM dapat memperluas pemasaran, menambah jumlah pelanggan, dan meningkatkan penjualan.