bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis
Authors: Sharma Supriya , Singh Swati , Shanbhag Swapna S. 
Published: July 2023

Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring and thinning. Presentation of case: A 59-year-old gentleman had poor visual recovery in the right eye (RE) following accidental carbide blast, 1-year before presenting to us. The visual acuity was counting fingers and clinical examination revealed cicatricial entropion involving the upper eyelid, total LSCD, corneal scarring with a central descemetocele and cataract in the RE. Prior to ocular surface reconstruction, entropion correction was performed. Three months later, penetrating keratoplasty combined with cataract surgery and intraocular lens implantation (penetrating keratoplasty (PK) triple), with autologous simple limbal epithelial transplantation (SLET) was performed. The visual acuity was 20/100, 18 months after the surgery, with a clear well-epithelized corneal graft and stable ocular surface. Discussion: LSCD is caused by a decrease in the population and /or function of the limbal epithelial stem cells. Limbal stem cell transplantation (LSCT) is warranted in eyes with total LSCD. In eyes with coexisting corneal scarring, LSCT alone may be inadequate to restore the vision. These eyes require simultaneous or sequential lamellar or full-thickness corneal transplantation for visual rehabilitation. Though, the existing literature favors a sequential approach, where LSCT is performed first followed by corneal transplantation, under certain circumstances such as a thin underlying cornea like in our case, corneal transplantation may have to be combined with LSCT to achieve optimal outcomes. Conclusion: Combining autologous SLET with PK can be performed for visual rehabilitation in eyes with unilateral total LSCD and underlying corneal thinning. Corneal and limbal graft survival is prolonged if existing adnexal comorbidities are addressed before any surgical intervention is planned and adequate time interval is allowed for the surface inflammation to subside.
Development of the lexicon, trained panel validation and sensory profiling of new ready-to-eat plant-based "meatballs" in tomato sauce
Authors: Talens Clara , Lago Maider , Illanes Eder , Baranda Ana , Ibargüen Mónica , Santa Cruz Elena 
Published: July 2023

Background: Providing educational content for children and parents can promote healthy nutritional habits. During the TITAN project, a pilot digital contest where participants have to developed ready-to-eat meatballs in sauce, using only plant-based ingredients, will be tested. The objective of this study was to develop the lexicon needed to objectively assess the sensory profile of this product. Methods: Eight judges were recruited and trained. Thirteen 1-hour sessions took place over three months. The steps followed were the selection of commercial reference, generation of descriptors, training of the panel, validation of the trained panel and product characterisation. The judges chose one commercial reference (using simple hedonic evaluation) to serve as a reference. The accepted intensity scale for the generated descriptors was from 0 (low intensity) to 9 (very intense). To test the first versions of the game, food product developers involved in the project, acted as participants, and used a mix of lentils, quinoa, and oats to enhance the commercial version. R-project software was used to analyse the performance of the panel and the sensory profiles. Results: A glossary with 14 descriptors was generated. The discriminatory capacity of the panel was confirmed by examining the significance of the product effect (p < 0.05). The product–judge interaction was not significant (p > 0.05) for most of the evaluated attributes, indicating a good degree of panel agreement. Overall, the panel was considered reproducible after 9 sessions. Although the appearance, firmness, fragility and chewiness were considered similar to the reference, juiciness and taste (understood as meaty flavour) of the new product were deemed improved. Conclusions: According to the panel, two of the most appreciated attributes associated with meat analogues, juiciness and taste, were improved compared to the commercial reference. Therefore, the first approach for further development of the contest/game was validated.
Context effects on object recognition in real-world environments: A study protocol
Authors: Nicholls Victoria I. , Alsbury-Nealy Benjamin , Krugliak Alexandra , Clarke Alex 
Published: July 2023

Background: The environments that we live in impact on our ability to recognise objects, with recognition being facilitated when objects appear in expected locations (congruent) compared to unexpected locations (incongruent). However, these findings are based on experiments where the object is isolated from its environment. Moreover, it is not clear which components of the recognition process are impacted by the environment. In this experiment, we seek to examine the impact real world environments have on object recognition. Specifically, we will use mobile electroencephalography (mEEG) and augmented reality (AR) to investigate how the visual and semantic processing aspects of object recognition are changed by the environment. Methods: We will use AR to place congruent and incongruent virtual objects around indoor and outdoor environments. During the experiment a total of 34 participants will walk around the environments and find these objects while we record their eye movements and neural signals. We will perform two primary analyses. First, we will analyse the event-related potential (ERP) data using paired samples t-tests in the N300/400 time windows in an attempt to replicate congruency effects on the N300/400. Second, we will use representational similarity analysis (RSA) and computational models of vision and semantics to determine how visual and semantic processes are changed by congruency. Conclusions: Based on previous literature, we hypothesise that scene-object congruence would facilitate object recognition. For ERPs, we predict a congruency effect in the N300/N400, and for RSA we predict that higher level visual and semantic information will be represented earlier for congruent scenes than incongruent scenes. By collecting mEEG data while participants are exploring a real-world environment, we will be able to determine the impact of a natural context on object recognition, and the different processing stages of object recognition.
Nash Equilibrium Problems of Polynomials
Authors: Nie Jiawang , Tang Xindong 
Published: July 2023

This paper studies Nash equilibrium problems that are given by polynomial functions. We formulate efficient polynomial optimization problems for computing Nash equilibria. The Moment-sum-of-squares relaxations are used to solve them. Under generic assumptions, the method can find a Nash equilibrium, if there is one. Moreover, it can find all Nash equilibria if there are finitely many ones of them. The method can also detect nonexistence if there is no Nash equilibrium. Funding: J. Nie was supported by the National Science Foundation [Grant DMS-2110780].
Managing Competition from Within and Outside: Using Strategic Inventory and Network Externality to Combat Copycats
Authors: Jin Chen , Wu Chenguang (Allen) , Chen Ying-Ju 
Published: July 2023

Problem definition: Prior studies have identified the role of downstream retailers’ strategic inventory in mitigating double marginalization within decentralized supply chains. Our work adds to this literature by introducing two relevant features that naturally appear in a dynamic environment: network externality and copycatting. We demonstrate how strategic inventory and network externality can be used to manage competition from within and outside the supply chain. Methodology/results: We develop a game-theoretical model to capture the strategic interaction within a brand-name supply chain, which enjoys positive externalities from early-period sales but faces competition from copycats in later periods. We show that copycats, on the one hand, deter the retailer’s strategic inventory by exerting external competition and on the other hand, can amplify the benefit of the retailer’s strategic inventory in allaying internal double marginalization and enhancing the supply chain’s external competitiveness. We further show that network externality, on the one hand, brings immediate gains to the supply chain’s external battle with copycats and on the other hand, creates internal inefficiency in the form of cross-period double marginalization best exhibited under the supplier’s dynamic contract. When network externality and strategic inventory are optimized jointly, we find that they are always complementary in increasing the supplier’s payoff but can be substitutive to the retailer under a large inventory cost and weak network externality. Managerial implications: Our work provides firms ways of managing decentralized supply chains in the face of copycats. We propose strategic inventory and network externality to combat copycats and provide normative guidance on their operating mechanisms. Funding: C. Jin received financial support from the Singapore Ministry of Education Academic Research Fund [Tier 1 Grant 251RES2101]. Y.-J. Chen received financial support from Hong Kong RGC [Grants GRF 16500821 and HKUST C6020-21GF]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2021.0182 .
Respuesta a la carta al editor de “Comentario al Estudio de reactogenicidad de la vacuna ARNm de COVID-19”
Authors: Ingles Torruella Joan , Gil Soto Rosa Maria , Sabaté Aguila Esther , García Grau Mercé , Pons Boronat Nina , Rubio Civit Adelaida , Bandera Baez Miriam , Moreno Martín Gustavo 
Published: July 2023

Querido editor,
Nuestro estudio tiene por objetivo, comparar los efectos adversos a corto plazo y sus consecuencias entre las vacunas RNAm, Commirnaty® (Pfizer) y Spikevax® (Moderna), así como, estos efectos adversos a corto plazo y sus consecuencias entre la primera y la segunda dosis de las citadas vacunas entre sí. Los posibles efectos adversos a largo plazo no eran objeto de nuestro estudio…
Effects of Rotary Tine Tool Velocity on Soil Reaction Forces, Power, and Energy Intensity
Authors: Kshetri Safal , Steward Brian L. , Tekeste Mehari Z. 
Published: July 2023

Highlights

Draft force and torque on a vertical rotary tine tool were studied for various longitudinal velocities and speed ratios.

Draft force increased with longitudinal velocity but decreased with speed ratio, and soil reaction torque increased with both longitudinal velocity and speed ratio.

Total power required by the tool increased with speed ratio, and energy intensity increased with speed ratio and longitudinal velocity, with substantial changes observed at higher velocities.

Abstract. Studying soil-tool interaction can provide valuable information on the actuation force and energy requirements of a weeding tool operating in soil. Soil-tine interaction was investigated for a vertical rotary tine tool that was intended to be used as a weeding tool for an automated mechanical intra-row weeder. The main objective of the research was to investigate the effects of linear and rotational velocities on soil reaction forces and power associated with actuation of the rotary tine tool in soil. A series of soil bin experiments were conducted in loam soil. Soil horizontal (draft) force and torque on the tool were measured at three longitudinal/travel velocities of 0.09 m s-1, 0.29 m s-1, and 0.5 m s-1 that were used to move the tool linearly across the soil bin length. The speed ratio, defined as the ratio of the longitudinal velocity to the peripheral velocity of the rotary tines, determined the rotational speeds required for the study. The draft force and torque were evaluated at four speed ratio levels (0, 1, 1.5, and 2). An Analysis of Variance (ANOVA) performed for statistical analysis using p &lt; 0.05 showed that both longitudinal velocity and speed ratio had significant main and interaction effects on the draft force and torque. In most cases, the draft force decreased while torque increased with increasing speed ratios for the different longitudinal velocities used in the study. Power and energy intensity were also calculated using draft force and torque measurements for different experimental settings. For increases in speed ratios, the power requirements for tool draft force decreased, whereas the power requirements for rotating the tool increased for each longitudinal velocity. At the highest test travel speed of 0.5 m s-1, the power decreased from 66 W to 28 W for draft and increased from 0 W to 76 W for rotation of the tool at increasing speed ratios. The maximum total power calculated for the tool was 110 W at 0.5 m s-1 and a speed ratio of 2. The study shows the changes in power and energy requirements of a vertical rotary tine tool for different operating parameters for weed control. This information could be valuable for optimizing the physical weeding process. Keywords: Energy intensity, Power, Rotary tool, Soil-tine interaction, Weed control.
Effects of mobile device use on emotional and behavioral problems in the CBCL among preschoolers: Do shared reading and maternal depression matter?
Authors: Wu Hsin-Yi , Lin Wen-Yi , Huang Jian-Pei , Lin Chen-Li , Au Heng-Kien , Lo Yu-Chun , Chien Ling-Chu , Chao Hsing Jasmine , Chen Yi-Hua 
Published: July 2023

Introduction
Although mobile devices are used ubiquitously, studies on their detrimental effects on preschoolers are limited. Furthermore, no study has considered shared reading and mobile device usage simultaneously. Therefore, this study examined the effects of mobile devices and shared reading on preschoolers’ development along with the effects of maternal depression on this association.

Materials and methods
Mothers of 202 children aged 2–5 years were recruited in Taiwan. Maternal self-reported questionnaires on mobile device usage, shared reading, and child’s emotional and behavioral development were collected. Multiple linear regression models were used for analyses.

Results
Mothers’ higher usage time on mobile devices and an education level of college or less were significantly associated with the child’s exceeding recommended use of mobile devices. Particularly among depressed mothers, preschoolers’ exceeding recommended use of mobile devices was associated with more sleep (β = 9.87, 95% confidence interval [CI] = 1.34, 18.40) and attention (β = 7.20, 95% CI = 1.50, 12.91) problems, whereas shared reading was associated with less somatic complaints (β = −16.19, 95% CI = −32.22, −0.15) and withdrawn (β = −21.50, 95% CI = −40.52, −2.47), compared with their respective counterparts.

Conclusion
Our study suggested the beneficial effects of shared reading. Moreover, we highlighted the adverse effects of preschoolers’ exceeding recommended use of mobile device on sleep and attention problems, especially for children of mothers with depression.
Third-trimester persistent maternal hypotension effects on late-onset small for gestational age and adverse perinatal outcomes
Authors: Eraslan Sahin Mefkure , Sahin Erdem , Kirlangic Mehmet Mete 
Published: July 2023

Introduction
The purpose of the current study was to examine whether third-trimester persistent maternal hypotension is related to small for gestational age (SGA) and adverse perinatal outcomes.

Methods
In this large retrospective cohort study, 6560 pregnant women were enrolled and divided into two groups according to maternal tension status: a normotensive group (n: 6290) and a persistent maternal hypotensive group (n: 270). Persistent maternal hypotension was defined as an SBP <100 mmHg and/or DBP <60 mmHg at three antenatal visits: visit 1 (260/7–296/7 gestation weeks), visit 2 (300/7–336/7 gestation weeks), and visit 3 (340/7–366/7 gestation weeks). Following the Delphi consensus criteria, a fetal growth restriction diagnosis was employed. The presence of an SGA neonate was the primary outcome of the study. SGA was defined as fetal abdominal circumference below the 10th percentile or fetal birth weight below the 10th percentile in the absence of abnormal Doppler findings. The secondary outcomes were defined as the presence of other adverse perinatal outcomes.

Results
The baseline characteristics of the study population were similar. We found that SGA rates were 6.3% in the control group and 7.0% in the persistent maternal hypotension group, which were statistically similar. In the present study, the secondary outcomes which prematurity, low 5-min Apgar score, and NICU admission were similarly between groups.

Discussion
Our results indicate that third-trimester persistent hypotension is not associated with SGA neonates or adverse perinatal outcomes. Hence, it can be concluded that third-trimester persistent hypotension is a physiological phenomenon during pregnancy that should not cause anxiety in mothers.
Nutritional status of tribal and non-tribal adults in rural Bangladesh: A comparative study
Authors: Karim Md. Reazul , Mamun Abu Sayed Md. Al , Hossain Md. Ripter , Islam Md. Nurul , Rana Md. Masud , Wadood Md. Abdul , Bose Kaushik , Bharati Premananda , Hossain Md. Golam 
Published: July 2023

Background
Nutritional status is an important indicator of health status among adults. However, to date, there exists scanty information on the nutritional status of tribal populations of Bangladesh. The aim of the study was to investigate the nutritional status of tribal (T) and non-tribal (NT) adult people living in the rural area of Rajshahi district, Bangladesh.

Methods
A total of 420 (72 T and 348 NT) households were studied. The samples were selected using multistage stratified sampling with proportional allocation. The nutritional status of adults was measured using body mass index (BMI). Descriptive statistics, t-test, ANOVA and Z-proportional test were utilized for data analysis.

Results
The study revealed that 8.3% and 9.2% of T and NT men were suffering from under nutrition respectively, while the corresponding figures in women were 12.5% and 10.1% respectively. Overall, 11.1% and 27.0% men, and 13.9% and 29.3% women T and NT were over-nourished respectively. The rate of over nutrition among T was significantly (p<0.05) higher than NT for both sexes. The mean weight and BMI of the NT men were significantly (p<0.01) higher than T men. The mean weight, height and BMI of NT women were higher (p<0.05) than T women. ANOVA demonstrated that the variation in BMI among education levels of NT men and the variation among occupation for both ethnicities were significant (p<0.01). The variation in BMI among education levels and occupation of T and NT women were significant (p<0.05), moreover ordinal logistic regression model demonstrated that hygienic toilet facilities and father’s occupation were predictors of nutritional status. The interaction effects of education and occupation, and education and household monthly income on BMI were significant (p<0.01) for T men and both T and NT women (p<0.05).

Conclusions
The prevalence of over-nutrition among NT is higher than T for both sexes. Some socio-economic and demographic factors were found as predictors of malnutrition. At least 12 of the 17 Sustainable Development Goals (SDGs) contain indicators that are highly related to nutrition, our findings can help Bangladesh Government for achieving SDGs by 2030. Appropriate nutritional intervention and awareness programmes can be initiated by the Government to ameliorate the burden of malnutrition among adults in the country.
Malaria infection and its association with socio-demographics, long lasting insecticide nets usage and hematological parameters among adolescent patients in rural Southwestern Nigeria
Authors: IBRAHIM Azeez Oyemomi , Agbesanwa Tosin Anthony , AREMU Shuaib Kayode , BELLO Ibrahim Sebutu , ELEGBEDE Olayide Toyin , GABRIEL-ALAYODE Olusegun Emmanuel , AJETUNMOBI Oluwaserimi Adewumi , ADEWOYE Kayode Rasaq , OLANREWAJU Temitope Moronkeji , ARIYIBI Ebenezer Kayode , OMONIJO Adetunji , SANNI Taofeek Adedayo , ALABI Ayodele Kamal , OLUSUYI Kolawole 
Published: July 2023

Background
There is increasing evidence suggesting that adolescents are contributing to the populations at risk of malaria. This study determined the prevalence of malaria infection among the adolescents and examined the associated determinants considering socio-demographic, Long Lasting Insecticide Nets (LLINs) usage, and hematological factors in rural Southwestern Nigeria.

Methods
A hospital-based cross-sectional study was conducted between July 2021 and September 2022 among 180 adolescents who were recruited at a tertiary health facility in rural Southwestern Nigeria. Interviewer administered questionnaire sought information on their socio-demographics and usage of LLINs. Venous blood samples were collected and processed for malaria parasite detection, ABO blood grouping, hemoglobin genotype, and packed cell volume. Data were analyzed using SPSS version 20. A p-value <0.05 was considered statistically significant.

Results
The prevalence of malaria infection was 71.1% (95% CI: 68.2%-73.8%). Lack of formal education (AOR = 2.094; 95% CI: 1.288–3.403), being a rural residence (AOR = 4.821; 95% CI: 2.805–8.287), not using LLINs (AOR = 1.950; 95% CI: 1.525–2.505), genotype AA (AOR = 3.420; 95% CI: 1.003–11.657), genotype AS (AOR = 3.574; 95%CI: 1.040–12.277), rhesus positive (AOR = 1.815; 95% CI:1.121–2.939), and severe anemia (AOR = 1.533; 95% CI: 1.273–1.846) were significantly associated with malaria infection.

Conclusion
The study revealed the prevalence of malaria infection among the adolescents in rural Southwestern Nigeria. There may be need to pay greater attention to adolescent populations for malaria intervention and control programs.
A new scoring system with simple preoperative parameters as predictors of early recurrence of pancreatic ductal adenocarcinoma
Authors: Shimagaki Tomonari , Sugimachi Keishi , Mano Yohei , Tomino Takahiro , Onishi Emi , Nakashima Yuichiro , Sugiyama Masahiko , Yamamoto Manabu , Morita Masaru , Shimokawa Mototsugu , Yoshizumi Tomoharu , Toh Yasushi 
Published: July 2023

Background
Pancreatic ductal adenocarcinoma (PDAC) often recurs early after radical resection, and such early recurrence (ER) is associated with a poor prognosis. Predicting ER is useful for determining the optimal treatment.

Methods
One hundred fifty-three patients who underwent pancreatectomy for PDAC were divided into an ER group (n = 54) and non-ER group (n = 99). Clinicopathological factors were compared between the groups, and the predictors of ER and prognosis after PDAC resection were examined.

Results
The ER group had a higher platelet count, higher platelet-to-lymphocyte ratio (PLR), higher preoperative CA19-9 concentration, higher SPan-1 concentration, larger tumor diameter, and more lymph node metastasis. The receiver operating characteristic (ROC) curve analysis identified cut-off values for PLR, carbohydrate antigen 19–9 (CA19-9), SPan-1, and tumor diameter. In the multivariate analysis, a high PLR, high CA19-9, and tumor diameter of >3.1 cm were independent predictors of ER after resection (all p < 0.05). When the parameter exceeded the cut-off level, 1 point was given, and the total score of the three factors was defined as the ER prediction score. Next, our new ER prediction model using PLR, CA19-9 and tumor diameter (Logit(p) = 1.6 + 1.2 × high PLR + 0.7 × high CA19-9 + 0.5 × tumor diameter > 3.1cm) distinguished ER with an area under the curve of 0.763, a sensitivity of 85.2%, and a specificity of 55.6%.

Conclusions
ER after resection of PDAC can be predicted by calculation of a score using the preoperative serum CA19-9 concentration, PLR, and tumor diameter.