bluuebunny/crossref_metadata_2025_split huggingface dataset:
Empirical Raman calibration of trioctahedral ferromagnesium chlorite minerals
Authors: Lamm Sarah N. , Lacroix Brice , Marshall C. P. , Lahfid Abdeltif , Gasda Patrick J. , Kempton Pamela D. , Trincal Vincent , Buatier Martine , Lanari Pierre , Vennemann Torsten 
Published: September 2023

AbstractChlorite is a common hydrated‐aluminous phyllosilicate mineral group that forms in most geological environments (e.g., hydrothermal, igneous, sedimentary, and metamorphic). The chemical composition of chlorite depends on several factors including temperature, pressure, fluid, and bulk rock composition. Raman spectroscopy is proposed as a quick and cost‐effective alternative to scanning electron microscopy and electron probe micro‐analysis, which involve complex sample preparation. In this paper, we demonstrate that Raman spectroscopy is a viable technique to determine the chemical composition of chlorite. Our results show that chlorite's Raman spectra changes quantitatively as a function of its chemical composition. Iron (Fe) and magnesium (Mg) content (APFU) is linearly correlated with the peak positions of three bands: Band 1 (99–104 cm−1), Band 8 (546–553 cm−1), and Band D (3,570–3,580 cm−1). In contrast, silicon (Si) and tetrahedral aluminum (AlIV) are correlated with a single band's position, Band 9b (663–679 cm−1). We derived 18 empirical rules from these correlations, aiding geoscientists in accurately identifying and determining chlorite composition using Raman spectroscopy. Moreover, this technique holds potential for determining chlorite's chemical composition during planetary exploration, leveraging existing Raman spectrometers deployed on Mars and for future space missions.
Muir–Torre syndrome and recent updates on screening guidelines: The link between colorectal tumors and sebaceous adenomas in unusual locations
Authors: Shaker Nada , Shaker Nuha , Abid Abdul , Shah Sahrish , Shakra Rafat Abu , Sangueza Omar P. 
Published: September 2023

AbstractBackgroundMuir–Torre syndrome (MTS) is a rare genetic disorder that is caused by mismatch repair (MMR) protein mutations. MTS increases the risk of developing skin and gastrointestinal tumors such as sebaceous adenomas (SAs), sebaceous carcinomas, colorectal cancer, endometrial cancer, and ovarian cancer. The risk of developing these types of tumors varies depending on the involved mutation and the individual's family history risk.Case PresentationA 47‐year‐old male presented with multiple skin lesions on the scalp, face, flank, and back. The examination revealed well‐circumscribed, dome‐shaped papules with a yellowish appearance with white oily material in the center. Histopathologic examination showed a well‐circumscribed sebaceous neoplasm consistent with a mixture of basaloid cells and lobules of bland‐appearing mature adipocytes that communicate directly to the surface epithelium. Focal cystic changes and peritumoral lymphocytic infiltrate were noted. Increased mitotic figures were seen in the basaloid cell component. The overall findings were consistent with the diagnosis of SAs. MMR staining showed preserved expression in MLH1 and PMS2 proteins, while MSH2 and MSH6 staining showed loss of protein expression. A screening colonoscopy showed numerous colon and rectal tumors, prompting concerns about the likelihood of MTS. Surgical intervention was pursued for complete resection. Histology revealed a diagnosis of mucinous adenocarcinoma/adenocarcinoma with mucinous features of the colon. The diagnosis of MTS was supported by molecular testing that revealed MSH2 germline mutation. The increased likelihood of MTS was attributed to the occurrence of SAs in unusual locations of the head and neck regions, unlike typical cases.ConclusionMTS is a rare clinical condition that necessitates prompt thorough evaluation and periodic surveillance. When SA is encountered in atypical locations, it is important to consider additional testing supported by immunohistochemical staining, molecular testing, and regular screening to exclude the likelihood of MTS.
Performance of Ultrasonography in the Diagnosis of Acute Colonic Diverticulitis
Authors: Perysinakis Iraklis , Klontzas Michail E. , Psaroudakis Ioannis G. , Karantanas Apostolos H. , de Bree Eelco , Vassalou Evangelia E. 
Published: September 2023

ObjectivesComputed tomography is regarded as the reference‐standard imaging modality for the assessment of acute left‐sided colonic diverticulitis (ALCD). However, its utility may be impaired by cost issues, limited availability, radiation exposure, and contrast‐related adverse effects. Ultrasonography is increasingly advocated as an alternative technique for evaluating ALCD, although there is variation regarding its accuracy in disease diagnosis and staging and in determining alternative diagnoses. The aim of this study was to assess the performance of ultrasonography in diagnosing ALCD, differentiating complicated from non‐complicated disease and defining alternative diseases related to left lower quadrant pain.MethodsWithin a 2‐year period, all consecutive adult patients with clinically suspected ALCD and available abdominal computed tomography were prospectively evaluated and planned to undergo an abdominal ultrasonographic examination, tailored to the assessment of left lower quadrant. Computed tomography (CT) was regarded as the reference standard.ResultsA total of 132 patients (60 males, 72 females; mean age: 61.3 ± 11 years) were included. The sensitivity, specificity, and area under curve of ultrasonography for diagnosing ALCD were 88.6, 84.9, and 86.8%, with positive and negative predictive values of 89.7 and 83.3%, respectively. The method had sensitivity, specificity, and area under curve of 77.8, 100, and 88.9%, respectively, for defining complicated disease. The area under the curve for the identification of alternative diseases in patients with left lower quadrant pain was 90.9%.ConclusionsUltrasonography has high diagnostic accuracy for diagnosing ALCD, differentiating complicated from non‐complicated disease and establishing alternative diagnoses related to left lower quadrant pain. A low threshold to get a CT should be maintained as not to miss cases that may mimic ALCD.
Ultrasound‐Guided Coccygeal Nerve Radiofrequency Ablation and Steroid Injection: Combination Therapy for Coccydynia
Authors: Can Ezgi , Yildiz Gokhan , Akkaya Ömer Taylan , Perdecioğlu Gevher Rabia Genç , Yürük Damla 
Published: September 2023

ObjectivesCoccydynia is characterized by pain in tailbone region, which affects the quality of life. Various interventional procedures are performed for coccydynia that is unresponsive to conservative treatment. This study aimed to evaluate the efficacy of ultrasound (US)‐guided radiofrequency ablation (RFA) and steroid injection of the coccygeal nerve in patients with idiopathic and traumatic coccydynia.MethodsIn this prospective study, 32 patients with coccydynia unresponsive to conservative treatments underwent US‐guided RFA of the coccygeal nerve. Coccygeal nerves were visualized at the level of the coccygeal cornua with US, 1 mL lidocaine 2% was injected into both areas and radiofrequency ablation was performed at 90°C for 60 seconds. After RFA, 2 mL dexamethasone and 2 mL bupivacaine 0.5% were injected. Visual Analog Scale (VAS) and Paris scales were used to evaluate the effect of treatment on pain and functionality before and at 1, 4, and 12 weeks after treatment.ResultsWe found that 54% of the patients had a >50% reduction in VAS score and 66% of the patients had a >50% reduction in Paris scores measured between baseline and week 12. Additionally, the main effect of time on the VAS and Paris scores was statistically significant (P < .001) in all measurements. Baseline P and VAS scores were higher than the post‐treatment measurements (P < .001).ConclusionsOur study showed that US‐guided steroid injection and RFA of the coccygeal nerve for chronic coccydynia significantly improved pain and function scores at weeks 1, 4, and 12. RFA also results in a lower rate of adverse events. This study is the first clinical trial of ultrasound‐guided coccygeal nerve RFA in patients with coccydynia. We believe that this new less invasive method may be an alternative to other interventional treatments.
Quality of Life Improvement in Concurrent Septorhinoplasty and Endoscopic Sinus Surgery
Authors: Bulut Olcay Cem , Lippert Burkard M. , Riedel Frank , Plath Michaela , Hohenberger Ralph 
Published: September 2023

ObjectivesSeptorhinoplasty (SRPL) and functional endoscopic sinus surgery (FESS) are two frequently performed surgeries to improve quality of life (QoL) in patients with nasal symptoms. It has been demonstrated as a safe combination regarding complication rates, but patient satisfaction in concurrent surgery has not been adequately studied yet.MethodsPatients undergoing sole FESS due to chronic rhinosinusitis (n = 57), sole SRPL (n = 148), and concurrent surgery (n = 62) were prospectively evaluated for their disease‐specific QoL before and one year after surgery. Each procedure was performed by the same surgeon (OCB). For SRPL, the patient‐reported outcome measures Rhinoplasty Outcomes Evaluation (ROE) and Functional Rhinoplasty Outcome Inventory (FROI‐17) were utilized, and for chronic rhinosinusitis, the Sino‐Nasal Outcome Test‐22 (SNOT22).ResultsAll three groups showed significant improvement in the postoperative QoL measurements (all p < 0.01). The postoperative improvements were slightly smaller in the concurrent surgery group compared with the single surgery groups measured with ROE (combined: +55.2 ± 9.3, single: +58.8 ± 9.8, p = 0.02), FROI total score (combined: +47.6 ± 5.2, single: +49 ± 5.4; p = 0.08) and SNOT22 (combined: +33.1 ± 6.7, single +34.5 ± 7, p = 0.26).ConclusionsSRPL, FESS, and combined surgery improve disease‐specific QoL. When applicable, surgeons may offer the benefits of a combined procedure without compromising the QoL gain.Level of Evidence3 Laryngoscope, 134:1239–1245, 2024
On complemented copies of the space c0 in spaces Cp(X,E)$C_p(X,E)$
Authors: Bargetz Christian , Kąkol Jerzy , Sobota Damian 
Published: September 2023

AbstractWe study the question for which Tychonoff spaces X and locally convex spaces E the space of continuous E‐valued functions on X contains a complemented copy of the space , both endowed with the pointwise topology. We provide a positive answer for a vast class of spaces, extending classical theorems of Cembranos, Freniche, and Domański and Drewnowski, proved for the case of Banach and Fréchet spaces . Also, for given infinite Tychonoff spaces X and Y, we show that contains a complemented copy of if and only if any of the spaces and contains such a subspace.
A Polymer Acceptor with Grafted Small Molecule Acceptor Unit for Efficient All Polymer Organic Solar Cells
Authors: Shi Wendi , Huang Yuzhong , Ma Kangqiao , Si Xiaodong , Feng Wanying , Wang Ruohan , Guo Jiaxin , Ma Wei , Wang Shijie , Clulow Andrew , Barnsley Lester , Yao Zhaoyang , Li Chenxi , Wan Xiangjian , Chen Yongsheng 
Published: September 2023

AbstractA polymer acceptor, named PX‐1, is designed and synthesized using a polymerization strategy with grafted small molecule acceptors. This design approach allows for the freedom of end groups while maintaining efficient terminal packing, enhancing π–π interactions, and facilitating charge transport. All‐polymer organic solar cells based on PM6: PX‐1 demonstrate a promising efficiency of 13.55%. The result presents an alternative pathway for the design of high‐efficiency polymer acceptors through the careful regulation of small molecule acceptor monomers and linker units.
Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions
Authors: Ye Jiatian , Zheng Lan , He Yuedong , Qi Xiaorong 
Published: September 2023

AbstractHuman papillomavirus (HPV) is the most prevalent sexually transmitted virus globally. Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical cancer, with 70% of cervical cancer cases associated with high‐risk types HPV16 and 18. HPV infection imposes a significant financial and psychological burden. Therefore, studying methods to eradicate HPV infection and halt the progression of precancerous lesions remains crucial. This review comprehensively explores the mechanisms underlying HPV‐related cervical lesions, including the viral life cycle, immune factors, epithelial cell malignant transformation, and host and environmental contributing factors. Additionally, we provide a comprehensive overview of treatment methods for HPV‐related cervical precancerous lesions and cervical cancer. Our focus is on immunotherapy, encompassing HPV therapeutic vaccines, immune checkpoint inhibitors, and advanced adoptive T cell therapy. Furthermore, we summarize the commonly employed drugs and other nonsurgical treatments currently utilized in clinical practice for managing HPV infection and associated cervical lesions. Gene editing technology is currently undergoing clinical research and, although not yet employed officially in clinical treatment of cervical lesions, numerous preclinical studies have substantiated its efficacy. Therefore, it holds promise as a precise treatment strategy for HPV‐related cervical lesions.
Impacts of platform coupons and power structure on an e‐commerce supply chain
Authors: Wan Nana 
Published: September 2023

AbstractThis paper considers an e‐commerce supply chain consisting of a manufacturer and an online platform and investigates the manufacturer's pricing decisions without and with platform coupons and the online platform's coupon decision under different power structures. In the manufacturer (platform) Stackelberg power structure, issuing platform coupons cannot (can) always stimulate the demand and benefit the manufacturer, the online platform, and the entire system. In the vertical Nash power structure, issuing platform coupons can always stimulate demand and benefit the manufacturer and the entire system but cannot always benefit the online platform.
Optimization of signal‐to‐noise ratio of laser heterodyne radiometer
Authors: Sun Chunyan , He Xinyu , Xu Ruoyu , Lu Sifan , Pan Xueping , Bai Jin 
Published: September 2023

AbstractThe ground‐based laser heterodyne radiometer (LHR), which exhibits the advantages of small size, high spectral resolution, and easy integration, has been used for the remote sensing detection of several gases to meet a wide range of needs. This study aims to optimize the laser heterodyne system for detecting CO2 gas by focusing on existing research. Firstly, using the all‐fiber laser heterodyne detection system built by our research group, the power spectrum associated with the radio frequency signals of the detection system is discussed under different conditions: under no irradiation, under sunlight only, under sunlight and laser irradiation at the absorption peak, and under a filter in the spectrum range of 185–270 MHz. Signal‐to‐noise ratios (SNRs) of the high‐resolution spectrum have been obtained using different filter bands of 185–270, 225–270, and 225–400 MHz. Finally, the filter in the 225–270 MHz band, which has the highest SNR, is selected. Consequently, the resolution is improved and the system is further optimized. Furthermore, an optical fiber attenuator is used to change the power of the local oscillator light entering the system, and hyperspectral spectra with varying percentages of input energy and total energy are obtained. When the laser attenuation reaches 40%, the optimal SNR of the system is 486 and can be further improved to meet the expected requirements. This study will provide insights for improving the applicability of laser heterodyne technology in atmospheric sounding.
A characterization of cardiac‐induced noise in R2* maps of the brain
Authors: Raynaud Quentin , Di Domenicantonio Giulia , Yerly Jérôme , Dardano Thomas , van Heeswijk Ruud B. , Lutti Antoine 
Published: September 2023

AbstractPurposeCardiac pulsation increases the noise level in brain maps of the transverse relaxation rate R2*. Cardiac‐induced noise is challenging to mitigate during the acquisition of R2* mapping data because its characteristics are unknown. In this work, we aim to characterize cardiac‐induced noise in brain maps of the MRI parameter R2*.MethodsWe designed a sampling strategy to acquire multi‐echo 3D data in 12 intervals of the cardiac cycle, monitored with a fingertip pulse‐oximeter. We measured the amplitude of cardiac‐induced noise in this data and assessed the effect of cardiac pulsation on R2* maps computed across echoes. The area of k‐space that contains most of the cardiac‐induced noise in R2* maps was then identified. Based on these characteristics, we introduced a tentative sampling strategy that aims to mitigate cardiac‐induced noise in R2* maps of the brain.ResultsIn inferior brain regions, cardiac pulsation accounts for R2* variations of up to 3 s−1 across the cardiac cycle (i.e., ∼35% of the overall variability). Cardiac‐induced fluctuations occur throughout the cardiac cycle, with a reduced intensity during the first quarter of the cycle. A total of 50% to 60% of the overall cardiac‐induced noise is localized near the k‐space center (k < 0.074 mm−1). The tentative cardiac noise mitigation strategy reduced the variability of R2* maps across repetitions by 11% in the brainstem and 6% across the whole brain.ConclusionWe provide a characterization of cardiac‐induced noise in brain R2* maps that can be used as a basis for the design of mitigation strategies during data acquisition.
Activation of the classical complement pathway in myasthenia gravis with acetylcholine receptor antibodies
Authors: Ozawa Yukiko , Uzawa Akiyuki , Onishi Yosuke , Yasuda Manato , Kojima Yuta , Kuwabara Satoshi 
Published: September 2023

AbstractIntroduction/AimsMyasthenia gravis (MG) is an autoimmune disease affecting the neuromuscular junction (NMJ) of skeletal muscle. Complement activation is one of the mechanisms by which anti–acetylcholine receptor (anti‐AChR) autoantibodies reduce synaptic transmission at the NMJ. In this study, we aimed to examine the activation of the complement pathways, including the classical pathway, as potential contributors to the pathogenesis of MG with anti‐AChR antibodies.MethodsIn this single‐center, observational study of 45 patients with anti‐AChR–antibody‐positive generalized MG, serum concentrations of major components of the complement pathways, including C1q, C5, C5a, soluble C5b‐9 (sC5b‐9), Ba, and complement factor H, were measured using an enzyme‐linked immunosorbent assay. A total of 25 patients with a non‐inflammatory neurological disorder served as controls. In addition, the relationships of complement activation with clinical characteristics were examined.ResultsThe patients with MG exhibited lower serum levels of C5 (p = .0001) and higher serum levels of sC5b‐9 (p = .004) compared with the control group. At about 6 months (range, 172–209 days) after the start of immunotherapy, serum levels of Ba were significantly higher than baseline levels (p = .002) and were associated with improvement in MG clinical scores.DiscussionHerein, we provide evidence for the activation of the classical complement pathway and its association with disease activity in anti‐AChR–antibody‐positive generalized MG.
A displacement‐driven approach to frictional contact mechanics
Authors: Rahmi Diah Puspita , Fleischhauer Robert , Kaliske Michael 
Published: September 2023

SummaryThe contribution at hand aims at a numerical method to represent contact between two or more different solid bodies. The proposed computational contact algorithm is based on a displacement‐driven approach to describe the geometrical constraint resulting from the impenetrability of the solid bodies in contact. A solution method of contact between one deformable and one rigid body is assumed for the initial computationally fast implementation of the underlying equations. Elastic or inelastic material behavior can be considered for the deformable body. Furthermore, the proposed approach is capable of finite deformations. Moreover, a node‐to‐segment (NTS) formulation is utilized for contact element discretization. Various numerical examples are presented to demonstrate the numerical method's applicability for different contact mechanics tasks. First, the presented examples verify the displacement‐driven approach by investigating its convergence behavior and consistency. Then, comparisons of solutions by the proposed formulation to the analytical solution and the penalty method are provided to validate its accuracy. Moreover, the stick and slip condition of large sliding motion in a frictional contact problem is successfully depicted.
Analysis of influencing factors of job demands of healthcare workers working in mobile cabin hospitals in China
Authors: Yi Hongmei , Wei Sha , Song Jingyan , Xiao Mingzhao , Huang Huanhuan , Luo Di , Zhao Qinghua 
Published: September 2023

AbstractAimTo explore the job demands of healthcare workers (HCWs) working in mobile cabin hospitals in Shanghai and identify the influencing factors.DesignThe study had a cross‐sectional design.MethodsUsing the convenience sampling method, we selected 1223 HCWs (medical team members) working in these mobile cabin hospitals during April–May 2022. The findings of the general information questionnaire and the hierarchy scale of job demands of HCWs working in mobile cabin hospitals were used for the investigation.ResultsThe total score of job demands of the included HCWs was 132.26 ± 9.53; the average score of the items was 4.73 ± 0.34. Multivariate linear regression analyses showed that the following HCWs had significantly higher job demands: female HCWs and HCWs who received psychological training or intervention during the COVID‐19 pandemic, were satisfied with the doctor/nurse–patient relationship, received support from family members/friends/colleagues, believed that the risk of working in mobile cabin hospitals was high, had adapted to the working environment of mobile cabin hospitals and had college/undergraduate level of education. They would benefit from increased social support and better training in terms of psychological coping mechanisms(both theoretical knowledge and applicable skills) and COVID‐19 prevention,control and treatment abilities.
Development of the Japanese version of the 30‐item Mystical Experience Questionnaire
Authors: Yonezawa Kengo , Tani Hideaki , Nakajima Shinichiro , Uchida Hiroyuki 
Published: September 2023

AbstractIntroductionPsychedelics have garnered increased attention as potential therapeutic options for various mental illnesses. Previous studies reported that psychedelics cause psychoactive effects through mystical experiences induced by these substances, including an altered state of consciousness. While this phenomenon is commonly assessed by the Mystical Experiences Questionnaire (MEQ30), a Japanese version of the MEQ30 has not been available. The aim of this study was to develop the Japanese version of the MEQ30.MethodsWe adhered to the “Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient‐Reported Outcomes (PRO) Measures: Report of the ISPOR Task Force for Translation and Cultural Adaptation” in our translation process. Two Japanese psychiatrists independently performed forward translations, from which a unified version was derived through reconciliation. This version was subsequently back‐translated into English and reviewed by the original authors for equivalency. The iterative revision process was carried out through ongoing discussions with the original authors until they approved the final back‐translated version.ResultsThe final, approved back‐translated version of the MEQ30 is presented in the accompanying figure. Additionally, the authorized Japanese version of the MEQ30 is included in the Appendix A.ConclusionsIn this study, we successfully developed a Japanese version of the MEQ30. This scale will facilitate the assessment of mystical experiences associated with psychedelic‐assisted therapy among Japanese speakers. Further research is warranted to evaluate the reliability and validity of this newly translated scale.