bluuebunny/crossref_metadata_2025_split huggingface dataset:
How I got here: Career influences on healthcare professionals who work with persons with intellectual and developmental disabilities
Authors: McCann Hannah P. , Smith Sydnie E. , Urbano Richard C. , Dykens Elisabeth M. , Hodapp Robert M. 
Published: May 2023

AbstractAlthough increasing the healthcare workforce serving those with intellectual and developmental disabilities (IDD) remains critical, we know little about how current healthcare workers began serving this population. Surveying 153 U.S.‐based healthcare professionals who work with persons with IDD, this study examined the presence, influence, and nature of their disability‐related experiences. The most common and influential experiences involved pre‐ and post‐professional disability training. Less frequent, albeit influential, experiences included being a sibling or having other family members with disabilities and working at disability‐related camps. First encounters with persons with IDD occurred during the child and adolescent (i.e., preprofessional) years for 38% of respondents, with slightly lower percentages occurring earlier (34%, involving family) or later (28%, during pre‐ or post‐professional training). Those with family or child–adolescent first encounters more often also reported disability experiences in subsequent periods. Respondents spoke of the formative effects of hands‐on disability training as well as of family and child–adolescent experiences, although some disability‐related careers also featured an element of chance. Practical and policy implications are discussed.
Business as usual? Donald Trump and US hegemony through the lens of dollar diplomacy in Argentina
Authors: Rowley Jude 
Published: May 2023

AbstractThe Trump presidency was an unwavering source of controversy and attention for four years; it can now be evaluated for its legacy. This article assesses the Trumpian contribution to US foreign policy, turning to the case study of US policy toward Argentina. Situating it in the wider historical context of traditional US “dollar diplomacy,” it argues that, despite warnings from the US foreign policy elite, Trump has not weakened US hegemony in Latin America, but conversely, has acted as an indicator of its strength. We contextualize Trump's influence on US hegemony by suggesting that the occupant of the White House had less of an effect on transforming the broader contours of US foreign policy than the deep‐rooted structural factors shaping it. By viewing US hegemony as a complex adaptive system, able to absorb changes such as the shift from Obama to Trump, it is possible to reconceptualize the way foreign policy is understood and evaluated in both the Latin American and the global context.
A multicentre external quality assessment: A first step to standardise PCR protocols for the diagnosis of histoplasmosis and coccidioidomycosis
Authors: Wilmes Dunja , Hagen Ferry , Verissimo Cristina , Alanio Alexandre , Rickerts Volker , Buitrago Maria José 
Published: May 2023

AbstractBackgroundIn‐house real‐time PCR (qPCR) is increasingly used to diagnose the so‐called endemic mycoses as commercial assays are not widely available.ObjectivesTo compare the performance of different molecular diagnostic assays for detecting Histoplasma capsulatum and Coccidioides spp. in five European reference laboratories.MethodsTwo blinded external quality assessment (EQA) panels were sent to each laboratory that performed the analysis with their in‐house assays. Both panels included a range of concentrations of H. capsulatum (n = 7) and Coccidioides spp. (n = 6), negative control and DNA from other fungi. Four laboratories used specific qPCRs, and one laboratory a broad‐range fungal conventional PCR (cPCR) and a specific cPCR for H. capsulatum with subsequent sequencing.ResultsqPCR assays were the most sensitive for the detection of H. capsulatum DNA. The lowest amount of H. capsulatum DNA detected was 1–4 fg, 0.1 pg and 10 pg for qPCRs, specific cPCR and broad‐range cPCR, respectively. False positive results occurred with high concentrations of Blastomyces dermatitidis DNA in two laboratories and with Emergomyces spp. in one laboratory. For the Coccidioides panel, the lowest amount of DNA detected was 1–16 fg by qPCRs and 10 pg with the broad‐range cPCR. One laboratory reported a false positive result by qPCR with high load of Uncinocarpus DNA.ConclusionAll five laboratories were able to correctly detect H. capsulatum and Coccidioides spp. DNA and qPCRs had a better performance than specific cPCR and broad‐range cPCR. EQAs may help standardise in‐house molecular tests for the so‐called endemic mycoses improving patient management.
Two cases of KRT1 mutation‐associated epidermolytic ichthyosis without typical epidermolytic hyperkeratosis in the neonatal skin lesions
Authors: Kim Taehee , Kim Soo‐Chan , Lee Sang Eun 
Published: May 2023

AbstractEpidermolytic ichthyosis (EI) is a rare genetic disorder of keratinization caused by mutations in either KRT1 or KRT10. Histopathologically, epidermolytic hyperkeratosis (EHK) is a hallmark of EI. Here, we report two EI cases in which KRT1 mutation was confirmed by molecular study, but without typical EHK present on skin biopsies performed within 1 week of age. Our cases demonstrate that EHK may not be evident in EI if skin biopsy is performed during the neonatal period.
Transcriptome profiling of Nephelium lappaceum: Sodium nitroprusside‐induced delays of postharvest browning
Authors: Zhang Ruining , Jiang Fan , He Xinrui , Yuan Zhouyu , Chen Ping , Zheng Zhongbing 
Published: May 2023

AbstractSodium nitroprusside (SNP), as a nitric oxide donor, is widely used in postharvest fruit physiology and metabolism. Our previous study has indicated that SNP plays a crucial role in postharvest browning control of rambutan, but the molecular mechanism underlying this process is still unclear. In this research, we investigated the gene expression and function of postharvest rambutan in response to SNP during browning. We found 7336 differentially expressed genes (DEGs), among which 2206 were upregulated and 5130 were downregulated. Gene Ontology (GO) enrichment as well as Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed, and the real‐time quantitative PCR (qPCR) data were consistent with transcriptome data. The DEGs relevant to rambutan pericarp browning were mainly involved in anthocyanin biosynthesis, phenolic oxidation, reactive oxygen species (ROS) production, and energy supply. It was shown that SNP regulated the synthesis and degradation of anthocyanins, accumulation of phenols, level of ROS and energy metabolism to suppress the postharvest browning of rambutan. Also, one WRKY transcription factor involved in ROS metabolism was observed to be differentially regulated. These findings add to our insights into the molecular mechanisms of the SNP‐induced browning delays of rambutan, which has implications for subsequent studies on molecular mechanisms of fruit browning.
Deep neural network classifier for multidimensional functional data
Authors: Wang Shuoyang , Cao Guanqun , Shang Zuofeng ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: May 2023

AbstractWe propose a new approach, called as functional deep neural network (FDNN), for classifying multidimensional functional data. Specifically, a deep neural network is trained based on the principal components of the training data which shall be used to predict the class label of a future data function. Unlike the popular functional discriminant analysis approaches which only work for one‐dimensional functional data, the proposed FDNN approach applies to general non‐Gaussian multidimensional functional data. Moreover, when the log density ratio possesses a locally connected functional modular structure, we show that FDNN achieves minimax optimality. The superiority of our approach is demonstrated through both simulated and real‐world datasets.
A new fossil family of aculeate wasp sheds light on early evolution of Apoidea (Hymenoptera)
Authors: Rosa Brunno B. , Melo Gabriel A. R. 
Published: May 2023

AbstractIn the present work, we describe a new fossil family of Apoidea supported by phylogenetic analyses involving both fossil and extant groups. †Burmasphecidae fam.n. is based on †Burmasphex Melo & Rosa, a genus described from Burmese amber. We include in this family the monotypic genus †Decasphex Zheng, Zhang & Rasnitsyn also from Burmese amber. Additionally, we describe two new genera and four new species in †Burmasphecidae fam.n.: †Burmasphex mirabilis sp.n.; †Simplisphex gen.n., containing S. scutellatus sp.n. and †S. burmensis sp.n.; and †Callisphex robustus gen. et sp.n. In our phylogenetic study, we extended a pre‐existing matrix of morphological data and analysed it under parsimony and Bayesian inference. In the Bayesian inference analyses, the morphological dataset was partitioned under a homoplasy criterion. We postulate the first phylogenetic hypotheses for the placement of †Angarosphecidae based on the type species, †Angarosphex myrmicopterus Rasnitsyn, plus a new Burmese amber taxon, †A. alethes sp.n. We demonstrate that †Burmasphecidae fam.n. clearly belongs to Apoidea and has a sister relationship with the other representatives of the superfamily. Our results indicate that †Burmasphecidae fam.n. and †Angarosphecidae are distinct lineages, with the second clearly more derived than the first. We discuss the phylogenetic relationships of these fossil lineages with extant groups of both Apoidea and other Aculeata, and present morphological evidence for the first time supporting the Formicidae + Apoidea clade. Finally, we indicate some considerations about the paleoenvironment and the nature of the Burmese amber biota, suggesting an alternative hypothesis to the island endemism described in previous works.
Holocene slip rates and their implications for seismic hazard along the Himalayan Frontal Thrust in western Himalayan Nahan salient
Authors: Kaushal Rahul Kumar , Dey Saptarshi , Guha Shantamoy , Chauhan Naveen , Singh Ajit 
Published: May 2023

AbstractProtracted interseismic locking of the low‐angle décollement of the Himalaya causes strain accumulation and results in growing slip deficit with time. Unlocking the frontal splay of the décollement during high‐magnitude earthquakes (Mw ≥6.5) may cause surface ruptures along the Himalayan Frontal Thrust (HFT). According to Paleoseismic investigations and observations on undeformed fluvial strath surfaces, the HFT in Nahan Salient has not experienced coseismic slip at least for the last six to seven centuries. Our new observations and chronological assessments on folded and faulted fluvial strath surfaces on the hanging wall of the HFT indicates a maximum slip rate of 10.4 ± 0.8–12.2 ± 0.8 mm/a (averaged over the last 7–8 ka). Seismic quiescence of 600–700 a results in a ~6.2–8.5 m slip deficit on the HFT which could trigger a Mw ≥7.7 earthquake. Our findings underline an enormous seismic risk prevailing in the Nahan area.
A multidisciplinary comparison of transfusion and perioperative support for high‐risk cardiac surgery at three large academic centres in North America
Authors: Jacobs Jeremy W. , Shih Andrew W. , Lombard Frederick W. , Bartoszko Justyna , Mullane Darren , Cserti‐Gadzewich Christine , Eichbaum Quentin 
Published: May 2023

AbstractCardiac surgery is associated with numerous peri‐ and post‐operative haemostatic complications and blood transfusion requirements. Complex procedures such as redo‐sternotomy heart transplantation or type A aortic dissection repairs are at high‐risk for severe coagulopathy and significant transfusion requirements. However, current practice guidelines do not specifically address high‐risk surgeries, resulting in variable practice. To optimise outcomes, a multidisciplinary approach to blood transfusion and haemostasis is critical. How individual institutions construct these multidisciplinary teams, delegate responsibilities, and build procedures may differ depending on the institution and availability of resources. In this article, we compare how the transfusion medicine services support their cardiac surgery and transplant programs at three large medical centres—Vanderbilt University Medical Center (the largest heart transplant centre in the world by volume in 2021), Toronto General Hospital‐University Health Network (a quaternary‐care centre in Canada's most populous city, performing more >20 heart transplants annually), and Vancouver General Hospital (a quaternary‐care centre that performs numerous high‐risk cardiac surgeries). This article discusses management from multiple perspectives, including the blood bank and perioperative environments, and highlights how institutions have evolved their programs in accordance with nation‐specific policies and provisions.
Sentinel lymph node mapping in the modern management of gynaecological malignancy
Authors: Collins Anna , Phillips Andrew 
Published: May 2023

Key content
Sentinel lymph node (SLN) biopsy is an alternative to systematic lymphadenectomy in the surgical staging of gynaecological malignancy. It is recommended in the management of vulval cancer and is increasingly used in endometrial and cervical cancer.
SLN failed mapping algorithms require that side‐specific lymphadenectomy should be performed in the case of failed mapping, and that suspicious lymph nodes are removed.
Ultrastaging protocols improve detection of lymph‐node metastasis and should be used for the pathological processing of SLNs.
Learning objectives
To understand the rationale, use and evidence for SLN biopsy in women with vulval, cervical and endometrial malignancy.
To appreciate the concepts behind the technical performance of SLN biopsy.
To understand the pathological processing of SLN samples and the implications this may have for the interpretation of results and adjuvant therapy.
Ethical issues
How to manage adjuvant therapy decisions in the context of micrometastases or isolated tumour cells in positive pelvic SLNs in cervical or endometrial cancer when the evidence‐base is limited.
Association between serum prostacyclin and cerebrovascular reactivity in healthy young and older adults
Authors: Corkery Adam T. , Miller Kathleen B. , Loeper Carissa A. , Tetri Laura H. , Pearson Andrew G. , Loggie Nicole A. , Howery Anna J. , Eldridge Marlowe W. , Barnes Jill N. 
Published: May 2023

AbstractPlatelet activation may contribute to age‐related cerebrovascular dysfunction by interacting with the endothelial cells that regulate the response to vasodilatory stimuli. This study evaluated the relationship between a platelet inhibitor, prostacyclin, and cerebrovascular reactivity (CVR) in healthy young (n = 35; 25 ± 4 years; 17 women, 18 men) and older (n = 12; 62 ± 2 years; 8 women, 4 men) adults, who were not daily aspirin users, before and after cyclooxygenase inhibition. Prostacyclin was determined by levels of 6‐keto‐prostaglandin F1α (6‐keto PGF1α) in the blood. CVR was assessed by measuring the middle cerebral artery blood velocity response to hypercapnia using transcranial Doppler ultrasound before (CON) and 90 min after cyclooxygenase inhibition with indomethacin (INDO). In young adults, there were no associations between prostacyclin and middle cerebral artery CVR during CON (r = −0.14, P = 0.415) or INDO (r = 0.27, P = 0.118). In older adults, associations between prostacyclin and middle cerebral artery CVR during CON (r = 0.53, P = 0.075) or INDO (r = –0.45, P = 0.136) did not reach the threshold for significance. We also evaluated the relationship between prostacyclin and the change in CVR between conditions (ΔCVR). We found no association between ΔCVR and prostacyclin in young adults (r = 0.27, P = 0.110); however, in older adults, those with higher baseline prostacyclin levels demonstrated significantly greater ΔCVR (r = –0.74, P = 0.005). In conclusion, older adults with higher serum prostacyclin, a platelet inhibitor, may rely more on cyclooxygenase products for cerebrovascular reactivity to hypercapnia.
Method to Establish Sound and Acceleration Levels of High Pressure Reducing Valves
Authors: Baumann Hans D. 
Published: May 2023

Abstract
Severe service control valves or better, high-pressure reducing valves can see inlet pressures in excess of 4000 psi. Such valves are found in industries ranging from gas or petroleum wells, to chemical plants and steam-producing power plants (Goodwin, “Specifying Control Valves for Severe Service Conditions”, INTECH FOCUS, November (2022), p. 20). Such valves convert high levels of kinetic energy through a process of conversion of sound-producing turbulence to a reduced pressure level. Less desired by-products such as conversion are sound pressure levels that can exceed 120 decibels, a sound that is comparable to standing next to a jet plane taking off. Part of this energy conversion manifests itself as mechanical vibration which can cause undesirable high pipe acceleration which, over time, could severely damage piping (Almasi. “Flow Induced Vibrations in Piping Systems”. P.I. PROCESS INSTRUMENTATION, July, 2020; Blake, 1986, “Mechanics of Flow Induced Sound and Vibrato,” Vol. II, Complex Flow-Structure Interactions, Academic Press, Orlando, FL). Proposed here is an easy computer programmable method to check the sound and acceleration levels associated with noisy valves. It is believed such a paper harmonizing all aspects of aerodynamic valve noise, such as sound pressure, sound power, vibration, and acceleration can be of value. The purpose of this paper is to explain how such acceleration levels are estimated. There are four steps involved: (1) calculate the sound pressure level (SPL) from given process data, (2) convert sound pressure level into sound power level (Lwi), and (3) find the associated maximum pipe internal peak frequency (fp). (4) Based on the sound power level and the peak frequency of the sound, calculate the acceleration of the pipe (in m/second2).
Introducing Empowered Consent to Deal With the Current Challenges in Applied Sport Psychology
Authors: Feddersen Niels Boysen 
Published: May 2023

There has been a paucity of literature discussing how to address consent procedures as part of ethics, practitioner development, and best practice in applied sport psychology. Several researchers have addressed ethical challenges (e.g., out-of-session contact, overidentification, time, and space). However, none have substantially considered the sport-specific issues related to consent, which sits at the heart of best practice. The scarcity of discussing consent is limiting sport psychology’s potential to establish itself as a more recognized profession. This article highlights some contextual issues that challenge the idea and efficacy of informed consent. It proposes adapting consent procedures in the collaboration between sport psychology practitioners and clients to better address the current contextual challenges in applied sport psychology. In doing so, the current paper introduces Empowered Consent, which is specifically designed to empower athletes and address challenges related to choosing interventions, contractual obligations, visibility in the environment, and staff trying to gain insights into confidential information. The author offers a model to enhance applied practice for those collaborating with athletes and other clients in sport.
Effects of Wearing Slippers While Obstacle Crossing in Healthy Young Adults: Strategy for Toe Clearance Enhancement and Prevention of Slipper Loss
Authors: Tanaka Kento , Sekiguchi Yusuke , Honda Keita , Izumi Shin-ichi 
Published: May 2023

Wearing loose footwear, such as slippers, poses a risk factor for tripping. Previous studies have examined obstacle crossing to find strategies to avoid tripping. However, the effect of wearing slippers on the likelihood of tripping remains unclear. Therefore, this study aimed to determine whether wearing slippers while level walking and obstacle crossing affects kinematic characteristics and muscle activity. Sixteen healthy, young adults performed two tasks (a) while wearing slippers and (b) while barefoot: (1) level walking and (2) crossing a 10-cm obstacle. Toe clearance, joint angles, muscle activity, and cocontraction were measured for both the leading and trailing lower limbs. In the slipper-wearing condition, knee flexion and hip flexion angles were significantly increased in the swing phase for the leading limb (p < .001 and p < .001, respectively) and trailing limb (p < .001 and p = .004, respectively) compared with the barefoot condition. Tibialis anterior activity (p = .01) and muscle cocontraction of the tibialis anterior and the medial head of the gastrocnemius (p = .047) were significantly increased in the swing phase of the trailing limb for the slipper-wearing condition compared with the barefoot condition in the obstacle crossing task. Wearing slippers increased knee and hip flexion angles, and muscle cocontraction of the tibialis anterior and medial head of gastrocnemius increased during obstacle crossing. The results revealed that obstacle crossing while wearing slippers would require foot fixation adjustment in addition to increased knee and hip flexion to avoid toe collision.
Effect of cognitive–behavioural therapy on resilience and relapse in adult patients with substance use disorder: a systematic review protocol
Authors: Mhaidat Ibraheem , Taherian Mohammad Reza , Hashemi Nazari Seyed Saeed , Mosavi-Jarrahi Alireza , Yeganeh Haniye , Al-Yateem Nabeel , Al Marzouqi Amina M , Rahman Syed Azizur 
Published: May 2023

IntroductionApproximately 0.5 million fatalities per year are attributed to substance use disorder (SUD). SUD is refractory to therapy and has a high relapse rate. Cognitive deficits are also common in patients with SUD. Cognitive–behavioural therapy (CBT) is a promising treatment that may build resilience and reduce relapse among people with SUD. Our planned systematic review aims to clarify the effect of CBT on resilience and the relapse rate in adult patients with SUD compared with treatment as usual or no intervention.Methods and analysisWe will search the Scopus, Web of Science, PubMed, Medline, Cochrane, EBSCO CINAHL, EMBASE and PsycINFO databases from inception to July 2023 for all relevant randomised controlled or quasiexperimental trials published in English. The follow-up period of included studies must be at least 8 weeks. The PICO (Population, intervention, control, and outcome) format was used to develop the search strategy. Search terms will be combined using boolean operators and have been customised for different databases. The Cochrane tool for randomised controlled trials will be used to assess the risk of bias in included studies. Extracted data will include bibliographic data, sample size, intervention method, summary of the findings, follow-up duration and effect sizes with standard errors. A random effects model will be used to combine effect measures. Subgroup analyses will be performed by CBT type, sex and SUD subtype, as applicable. I2statistics will be used to evaluate heterogeneity, and funnel plots will be used to address publication bias. If we detect significant heterogeneity, the findings will be reported as a systematic review without a meta-analysis.Ethics and disseminationEthical approval is not required for this study. The findings will be submitted for publication in a peer-reviewed journal.PROSPERO registration numberCRD42022344596.