bluuebunny/crossref_metadata_2025_split huggingface dataset:
National strategies for coordinating process safety and COVID‐19 pandemic control in China
Authors: Niu Yi , Fan Yunxiao , Liu Xiaobing , Han Dandan , Ju Xing 
Published: August 2023

AbstractDuring the COVID‐19 pandemic, while China blocked the spread of the coronavirus, its process safety status still maintained a positive trend. Hence, an in‐depth exploration of China's experience and lessons in coordinating epidemic control and process safety is an urgent need to exchange knowledge with other countries to prevent similar catastrophes. This paper comprehensively traces China's national strategies in coordinating epidemic control and safety regulation since the end of 2019 through information collection, literature surveys, and investigative interviews. According to the characteristics of these strategies, China's anti‐pandemic process is divided into three stages: outbreak, concentrated resumption of work, and normalization of epidemic prevention. On this basis, the main risks of each stage and the response measures taken by the Chinese government are further subdivided. Furthermore, the changes brought about by COVID‐19 on Chinese safety regulators are also discussed.
Cultural capital and underdevelopment in less developed countries: The case of northern Ghana
Authors: Klutsey Jonas Quashie , Adusei‐Asante Kwadwo , Nunfam Victor Fannam 
Published: August 2023

AbstractDevelopment paradigms under the sustainable development goals (SDGs) identify cultural capital as an indispensable asset for development in less developed countries. However, the phenomenon of culture and underdevelopment nexus has attracted little research attention in Ghana. The study used modernization theory and ethnographic research methodology to explore the role of cultural capital deficits in northern Ghana's underdevelopment. Our findings suggest a close correlation between cultural capital and underdevelopment relative to unethical attitudinal standards, value deficits, and an anti‐development mindset. We recommend the inclusion of cultural reorientation in the design of development intervention programs to uphold high integrity standards. We further suggest that the curriculum and concept of quality education in schools should be broadened to include inculcating high‐value standards. Our study has contributed to academic discourses on cultural capital's role in the search for sustainable development in less developed countries, particularly in implementing the SDGs.
Environmental education for sustainable development in Bangladesh and its challenges
Authors: Uddin Md. Kamal 
Published: August 2023

AbstractEnvironmental Education is very vital to reaching the agenda of Sustainable Development Goals. However, a lack of environmental awareness and gaps in theoretical knowledge and its practices still exists in Bangladesh. Therefore, this research aims to understand the students' perceptions of whether and how their behavior is environment‐friendly to achieve sustainable development goals. It also addresses teachers' perceptions of what are the shortcomings of environmental education in Bangladesh. It uses qualitative and quantitative data collection and analysis techniques based on in‐depth interviews, surveys among different categories of participants, and classroom observation. The article finds that the level of Environmental Education and students' awareness of the environment is inadequate. Some teachers believe that Environmental Education is not better in Bangladesh due to the absence of practical learning of Environmental Education, lack of motivations and actions, institutional weakness, inadequate policies, poor implementation, and cultural and traditional beliefs. Thus, this article argues that Bangladeshi Environmental Education is insufficient to change the students' behavior towards the environment, making it difficult for the country to ensure Sustainable Development.
A systematic review and meta‐analysis of the association between anxiety symptoms and coping in family carers of dependent people aged 18 and over
Authors: Muñoz‐Cruz Juan Carlos , López‐Martínez Catalina , Orgeta Vasiliki , Del‐Pino‐Casado Rafael 
Published: August 2023

AbstractAnxiety symptoms are prevalent in family carers of dependent people. Despite accumulating evidence in the area, there are still inconsistent findings on the association between carer anxiety symptoms and coping strategies. The aim of our study was to systematically analyse the relationship between anxiety symptoms and coping strategies in carers of dependent adults aged 18 years and older, and examine possible sources of heterogeneity in the results. The study design was a systematic review and meta‐analysis. We searched several international databases (Pubmed, CINAHL, PsycINFO and LILACS) from June 2022 up to February 2023. We followed the preferred reporting items for systematic reviews and meta‐analyses statement and performed several subgroup analyses to examine whether study design, cause of dependency and whether or not controlling for various biases influenced results. Forty‐one studies were included in the review. We found significant associations between greater use of dysfunctional coping and higher anxiety symptoms. Greater use of problem‐focused coping was associated with lower anxiety symptoms in carers of frail older people, but higher anxiety in carers of people surviving cancer. Emotion‐focused coping and some of its individual strategies, such as acceptance and positive reappraisal, in probabilistic samples, were associated with lower anxiety symptoms across all groups. Most of the studies included in this review were cross‐sectional. Evidence overall indicates that only specific dimensions and strategies of coping are significantly associated with anxiety symptoms in family carers. These findings should be considered when developing future interventions supporting carers.
SERS Sensing of Dopamine with Fe(III)‐Sensitized Nanogaps in Recleanable AuNP Monolayer Films
Authors: Niihori Marika , Földes Tamás , Readman Charlie A , Arul Rakesh , Grys David‐Benjamin , Nijs Bart de , Rosta Edina , Baumberg Jeremy J 
Published: August 2023

AbstractSensing of neurotransmitters (NTs) down to nmconcentrations is demonstrated by utilizing self‐assembled monolayers of plasmonic 60 nm Au nanoparticles in close‐packed arrays immobilized onto glass substrates. Multiplicative surface‐enhanced Raman spectroscopy enhancements are achieved by integrating Fe(III) sensitizers into the precisely‐defined <1 nm nanogaps, to target dopamine (DA) sensing. The transparent glass substrates allow for efficient access from both sides of the monolayer aggregate films by fluid and light, allowing repeated sensing in different analytes. Repeated reusability after analyte sensing is shown through oxygen plasma cleaning protocols, which restore pristine conditions for the nanogaps. Examining binding competition in multiplexed sensing of two catecholamine NTs, DA and epinephrine, reveals their bidentate binding and their interactions. These systems are promising for widespread microfluidic integration enabling a wide range of continuous biofluid monitoring for applications in precision health.
Engineering 2D MXene and LDH into 3D Hollow Framework for Boosting Photothermal Energy Storage and Microwave Absorption
Authors: Gao Yan , Lin Jinjie , Chen Xiao , Tang Zhaodi , Qin Geng , Wang Ge 
Published: August 2023

Abstract2D MXene is highly preferred for photothermal energy conversion and microwave absorption. However, the aggregation issue, insufficient dielectric loss capacity, and lack of magnetic loss capacity for MXene severely hinder its practical applications. Herein, the authors propose multi‐dimensional nanostructure engineering to electrostatically assemble 2D MXene and layered double hydroxides (LDH) derived from ZIF‐67 polyhedron into a 3D hollow framework (LDH@MXene), and subsequently calcined to construct a Co nanoparticle‐modified 3D hollow C‐LDH@MXene framework to encapsulate a paraffin wax (PW) phase change material (PCM). The 3D hollow C‐LDH@MXene framework not only prevents 2D MXene from aggregation but also contributes a high thermal energy storage density (131.04 J g−1). Benefiting from a 3D conductive network facilitating the rapid transport of photons and phonons from the interface to the interior and the synergistic localized surface plasmon resonance (LSPR) effect of MXene and Co magnetic nanoparticles, the C‐LDH@MXene‐PW composite PCM yielded a high photothermal storage efficiency of 96.52%. Besides, C‐LDH@MXene‐PW composite PCMs also exhibited efficient microwave absorption with a minimum reflection loss of −20.87 dB at 13.30 GHz with a matching thickness of only 2 mm. This distinctive design provides constructive references for the development of integrated composite materials for energy storage and microwave absorption.
Natural Antioxidant‐Based Nanodrug for Atherosclerosis Treatment
Authors: Lu Xiaoluan , He Zhongshan , Xiao Xiao , Wei Xuelian , Song Xiangrong , Zhang Shiyong 
Published: August 2023

AbstractNatural antioxidants are always considered as candidates for the antioxidative therapy of atherosclerosis (AS) due to their good safety profile. However, restricted to their limited reactive oxygen species (ROS) elimination and rapid metabolism, the natural antioxidants’ treatment suffers from the undesirable clinical outcomes. Herein, a new natural antioxidant‐based nanodrug (VC@cLAVs) that can overcome above issues is developed to treat AS by loading natural antioxidant vitamin C (VC) into the natural antioxidant lipoic acid (LA)‐constructed cross‐linked vesicles. This integration not only greatly increases the blood half‐life of natural antioxidants, but also amplifies the antioxidation capacity by the mutual recycling of two redox pairs LA/DHLA (reduced form of LA) and VC/DHA (oxidized form of VC). In vivo results disclose that VC@cLAVs decreases the apolipoprotein E‐deficient mice's plaque area from 52% to 13%, much lower than those of free VC (≈45%) and LA (≈38%). This natural antioxidant‐based nanodrug holds great potential in clinics.
Empirical exploration of critical challenges of requirements implementation in global software development
Authors: Yaseen Muhammad 
Published: August 2023

AbstractRequirements collection is difficult and a critical phase of software development life cycle, in particular in a global software development (GSD) environment. In GSD, clients and vendors are physically separated such that there exist challenges such as lack of face‐to‐face communication, language differences, culture variation, and time zone differences. The objective of current research is to identify critical challenges of requirement engineering in GSD. There is no work done yet to empirically analyze all possible challenges via questionnaire survey from software industries. This research paper empirically investigates and analyze the identified challenges from systematic literature review (SLR) based on a questionnaire survey. For this purpose, 50 respondents from different countries are organized. From this research, 13 challenges during requirements implementation in the context of GSD have been identified previously via SLR. These challenges were then evaluated using an empirical approach of questionnaire survey. The results from respondents were analyzed based on type of respondents, level of experience of respondents, and from client–vendor perspective. Finally, the challenges were prioritized based on its frequency of occurrences from the SLR and the questionnaire survey. The relationships between the challenges and the survey results were evaluated using the Spearman's correlation coefficient. The results produced a 0.835 Spearman's correlation coefficient at significance levelρ = 0.000, which showed a strong positive correlation between the outcome of SLR and survey with no significant difference. The implication of this research work lies in both fundamental and practical perspective. The prioritized set of challenges was provided based on SLR, and questionnaire survey acts as a knowledge base for both researchers and industrial practitioners. This work will help researchers to identify challenges in GSD projects or other software engineering areas.
A framework to support interoperable Game‐based Assessments as a Service (GBAaaS): Design, development, and use cases
Authors: Gomez Manuel J. , Ruipérez‐Valiente José A. , García Clemente Félix J. 
Published: August 2023

AbstractDuring the last few years, there has been increasing attention paid to serious games (SGs), which are games used for non‐entertainment purposes. SGs offer the potential for more valid and reliable assessments compared to traditional methods such as paper‐and‐pencil tests. However, the incorporation of assessment features into SGs is still in its early stages, requiring specific design efforts for each game and adding significant time to the design of Game‐based Assessments (GBAs). In this research, we present a completely novel framework that aims to perform interoperable GBAs by: (a) integrating a common GBA ontology model to process RDF data; (b) developing in‐game metrics to infer useful information and assess learners; (c) integrating a service API to provide an easy way to interact with the framework. We then validate our approach through performance evaluation and two use cases, demonstrating its effectiveness in real‐world scenarios with large‐scale datasets. Our results show that the developed framework achieves excellent performance, replicating metrics from previous literature. We anticipate that our work will help alleviate current limitations in the field and facilitate the deployment of GBAs as a Service.
“Playing with” and “Letting go”: Employing theoretical frameworks and methodologies to examine Black women's experiences in higher education
Authors: Porter Christa J. 
Published: August 2023

AbstractAuthor overviews interdisciplinary and culturally relevant theoretical/conceptual frameworks and methodologies researchers and theorists have employed to examine Black women's experiences in higher education as students, administrators, and faculty. In conversation with literature and her lived experiences, the author offers three lessons for Black women and those seeking to employ critical frameworks and methodologies: (1) do your research; (2) play with theory and let go; and (3) align positionality, epistemology, and praxis.
Shining the light: Black women thriving in graduate school
Authors: Jones Tamara Bertrand , Brewster Brittany , Matthews Dawn Y. 
Published: August 2023

AbstractIn this article, authors examine literature on the enrollment, degree attainment, and experiences of Black women graduate students. Authors use socialization to examine the failures of academia to account for Black women's intersectional identities and identify ways administrators and faculty can further support these women's success.
Ertüchtigung der Rheinbrücke Maxau
Authors: Weidner Philipp , Schneider Lukas , Ruff Daniel C. , Ummenhofer Thomas 
Published: August 2023

AbstractDurch die Belastung aus dem stetig zunehmenden Verkehrsaufkommen traten an der orthotropen Fahrbahnplatte der Rheinbrücke Maxau Ermüdungsschäden auf, die eine Ertüchtigung der Fahrbahn erforderlich machten. Hierzu wurde eine Aufbetonplatte aus hochfestem Beton (HFB) auf dem Deckblech aufgebracht. Die Versuchsanstalt für Stahl, Holz und Steine des Karlsruher Instituts für Technologie (KIT) begleitete die Ertüchtigungsmaßnahme messtechnisch. Dieser Beitrag stellt die erhaltenen Messergebnisse vor, geht auf die erzielten Effekte der Sanierungsmaßnahme ein und zieht Rückschlüsse auf deren Wirksamkeit. Zusätzliche numerische Untersuchungen belegen die durch die Maßnahme erzeugte Reduktion ermüdungswirksamer Beanspruchungen in der orthotropen Fahrbahnplatte, die auf die verbesserte Lastverteilung zurückzuführen ist, die sich mit den messtechnischen Ergebnissen deckt.
Radioprotective efficacy of Astilbin in mitigating radiation‐induced lung injury through inhibition of p53 acetylation
Authors: Liang Lixing , Huang Yaqin , Chen Liuyin , Shi Zhiling , Wang Housheng , Zhang Tingting , Li Zhixun , Mi Jinglin , Fan Ting , Lu Yushuang , Chen Fuli , Huang Weimei , Hu Kai 
Published: August 2023

AbstractRadiation‐induced lung injury (RILI) is a common side effect in thoracic tumor patients undergoing radiotherapy. At present, there is no ideal radio‐protective agent which is widely used in RILI treatment. Astilbin (AST), a bioactive flavonoid, exhibits various biological effects, including anti‐inflammatory, antioxidant, and anti‐fibrotic activities, which partly result from reducing oxidative stress and inflammation in various pathogenic conditions. However, the protective efficacy of AST to ameliorate RILI has not been reported. In this study, we employed network pharmacology, RNA sequencing, and experimental evaluation to reveal the effects and pharmacological mechanism of AST to treat RILI in vivo and in vitro. We observed that AST reduced radiation‐induced apoptosis, DNA damage, inflammatory reactions, and the reactive oxygen species (ROS) level in human normal lung epithelial cells BEAS‐2B. Further study showed that AST treatment significantly ameliorated RILI by reducing the radiation‐induced pathology changes and inflammatory reaction of lung tissue in C57BL/6J mice. Mechanistically, the expression of epithelial‐mesenchymal transition (EMT) markers and radiation‐triggered acetylation of the p53 protein were alleviated by AST treatment. Furthermore, AST alleviated the acetylation of p53 after intervention of Trichostatin A (TSA). Our data indicate that AST can alleviate RILI by inhibiting inflammatory reactions and the EMT process through decreasing the expression of p53 acetylation. In conclusion, our study suggests that AST has great potential to be a new protective and therapeutic compound for RILI.
Improving comparability across cognitive training trials for brain aging: A focus on interoperability
Authors: Turnbull Adam , Seitz Aaron , Lin Feng V. 
Published: August 2023

AbstractCognitive training may promote healthy brain aging and prevent dementia, but results from individual studies are inconsistent. There are disagreements on how to evaluate cognitive training interventions between clinical and basic scientists. Individual labs typically create their own assessment and training materials, leading to difficulties reproducing methods. Here, we advocate for improved interoperability: the exchange and cooperative development of a consensus for cognitive training design, analysis, and result interpretation. We outline five guiding principles for improving interoperability: (i) design interoperability, developing standard design and analysis models; (ii) material interoperability, promoting sharing of materials; (iii) interoperability incentives; (iv) privacy and security norms, ensuring adherence to accepted ethical standards; and (v) interpretability prioritization, encouraging a shared focus on neurobiological mechanisms to improve clinical relevance. Improving interoperability will allow us to develop scientifically optimized, clinically useful cognitive training programs to slow/prevent brain aging.HIGHLIGHTS
Interoperability facilitates progress via resource sharing and comparability.
Better interoperability is needed in cognitive training for brain aging research.
We adapt an interoperability framework to cognitive training research.
We suggest five guiding principles for improved interoperability.
We propose an open‐source pipeline to facilitate interoperability.
Bridging the rodent to human translational gap: Marmosets as model systems for the study of Alzheimer's disease
Authors: Sukoff Rizzo Stacey J. , Homanics Gregg , Schaeffer David J. , Schaeffer Lauren , Park Jung Eun , Oluoch Julia , Zhang Tingting , Haber Annat , Seyfried Nicholas T. , Paten Benedict , Greenwood Anna , Murai Takeshi , Choi Sang Ho , Huhe Hasi , Kofler Julia , Strick Peter L. , Carter Gregory W. , Silva Afonso C. 
Published: August 2023

AbstractIntroductionOur limited understanding of the mechanisms that trigger the emergence of Alzheimer's disease (AD) has contributed to the lack of interventions that stop, prevent, or fully treat this disease. We believe that the development of a non‐human primate model of AD will be an essential step toward overcoming limitations of other model systems and is crucial for investigating primate‐specific mechanisms underlying the cellular and molecular root causes of the pathogenesis and progression of AD.MethodsA new consortium has been established with funding support from the National Institute on Aging aimed at the generation, characterization, and validation of Marmosets As Research Models of AD (MARMO‐AD). This consortium will study gene‐edited marmoset models carrying genetic risk for AD and wild‐type genetically diverse aging marmosets from birth throughout their lifespan, using non‐invasive longitudinal assessments. These include characterizing the genetic, molecular, functional, behavioral, cognitive, and pathological features of aging and AD.ResultsThe consortium successfully generated viable founders carrying PSEN1 mutations in C410Y and A426P using CRISPR/Cas9 approaches, with germline transmission demonstrated in the C410Y line. Longitudinal characterization of these models, their germline offspring, and normal aging outbred marmosets is ongoing. All data and resources from this consortium will be shared with the greater AD research community.DiscussionBy establishing marmoset models of AD, we will be able to investigate primate‐specific cellular and molecular root causes that underlie the pathogenesis and progression of AD, overcome limitations of other model organisms, and support future translational studies to accelerate the pace of bringing therapies to patients.
Topology of SU(N) lattice gauge theories coupled with ℤN 2-form gauge fields
Authors: Abe Motokazu , Morikawa Okuto , Onoda Soma , Suzuki Hiroshi , Tanizaki Yuya 
Published: August 2023

Abstract
We extend the definition of Lüscher’s lattice topological charge to the case of 4d SU(N) gauge fields coupled with ℤN 2-form gauge fields. This result is achieved while maintaining the locality, the SU(N) gauge invariance, and ℤN 1-form gauge invariance, and we find that the manifest 1-form gauge invariance plays the central role in our construction. This result gives the lattice regularized derivation of the mixed ’t Hooft anomaly in pure SU(N) Yang-Mills theory between its ℤN 1-form symmetry and the θ periodicity.