bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chronic Tracheoesophageal Fistula Successfully Treated Using an Amplatzer Closure Device Under Endoscopic Visualization
Authors: Stawinski Peter M. , Dziadkowiec Karolina N. , Henkes Nichole C. , McMillan Natasha , Rosenkranz Laura A. 
Published: February 2023

ABSTRACT
In patients with severe comorbidities or those who are critically ill, chronic or recurrent tracheoesophageal fistulas may be successfully closed using an Amplatzer device. We present the case of a chronic tracheoesophageal fistula causing dysphagia and aspiration pneumonia, which was successfully repaired using an Amplatzer device.
Left-Sided Colonic Tuberculosis Presenting as Colonic Stricture: A Rare Presentation of a Common Disease
Authors: Abdul Jabbar Shabana , Selvakumar B. , Varshney Vaibhav Kumar , Sharma Indu , Khera Sudeep , Hussain Sabir 
Published: February 2023

ABSTRACT
Gastrointestinal tuberculosis (TB) mainly presents as an ileocecal disease, and colonic TB is more often seen with terminal ileal involvement. Isolated involvement of the descending colon by TB is uncommon and usually presents with chronic colitis. An acute presentation as intestinal obstruction because of tubercular stricture of the descending colon has not been reported. We encountered a young woman who presented with features of acute bowel obstruction. On evaluation, she was diagnosed with a case of descending colon stricture with a provisional diagnosis of malignant colonic stricture. Left hemicolectomy was performed, and histopathology revealed it to be tubercular stricture. Antitubercular therapy was given for 9 months, and she is doing well at follow-up. A differential diagnosis of TB at an unusual location should always be considered even when presented with atypical symptoms, especially for patients from the endemic zone of TB.
Dampak Variabilitas Iklim Inter-Annual (El Niño, La Niña) Terhadap Curah Hujan dan Anomali Tinggi Muka Laut di Pantai Utara Jawa Tengah
Authors: Yustiana Meida , Zainuri Muhammad , Sugianto Denny Nugroho , Batubara Mahardiani Putri Naulia , Hidayat Anistia Malinda 
Published: February 2023

El Niño dan La Niña memiliki pengaruh signifikan terhadap dinamika cuaca di wilayah Indonesia. Oleh karena itu, penelitian ini bertujuan untuk mengetahui dampak fenomena tersebut terhadap curah hujan (CH) dan anomali tinggi muka laut (TML) di Pantai Utara Jawa Tengah meliputi wilayah Brebes, Pemalang, Pekalongan dan Semarang menggunakan analisis kuantitatif deskriptif selama 1993 – 2020. Data yang digunakan pada penelitian ini adalah anomali TML, anomali suhu permukaan laut, dan data observasi CH bulanan dari pos hujan Pusdataru dan BMKG. Data tersebut ditampilkan dalam bentuk grafik anomali CH dan grafik overlay indeks Nino 3.4 dan anomali TML yang dikelompokkan berdasarkan data komposit 3 bulan. Hasil analisis menunjukkan bahwa pada periode pengamatan terjadi 2 kali El Niño sangat kuat pada November 1997 dan November 2015 dan juga 2 kali La Niña kuat pada Januari 2000 dan Januari 2008 dengan periode perulangan rerata setiap 8 tahun. Hubungan signifikan antara El Niño dan La Niña yang diwakili oleh indeks Nino 3.4 terhadap CH di Indonesia terjadi pada periode September-Oktober-November (SON), dengan nilai koefisien korelasi -0.53692 – (-0.7304). Masih dalam periode yang sama, hubungan anomali CH dan anomali TML juga menunjukkan nilai koefisien korelasi tertinggi di Semarang, Pekalongan dan Pemalang sebesar 0.546202 - 0.676914. El Niño and La Niña are two of several components of climate variability which has significant influence toward weather dynamics over Indonesia, including on the North Coast of Central Java. For this reason, this research aims to determine the impact of these two phenomena on rainfall and sea level anomaly (SLA) on the North Coast of Central Java covering Brebes, Pemalang, Pekalongan, and Semarang Regions using descriptive quantitative analysis using data from 1993 – 2020. The data used in this study were SLA, sea surface temperature anomaly in the Nino 3.4 region, and monthly rainfall observation data from the Pusdataru and BMKG rain posts, displayed in the form of a rainfall anomaly graph and an overlay graph of the Nino 3.4 index and SLA and grouped based on 3 months composite data. The analysis result showed that during the observation period there were two strong El Niño, in November 1997 and 2015, and also two strong La Niña in January 2000 and 2008 with a repeating period every eight years. The significant relationship between El Niño and La Niña represented by the Nino index 3.4 on rainfall in Indonesia occurred in September-October-November (SON), with a correlation coefficient of -0.53692 – (-0.7304). Still in the same period, the relationship between rainfall anomaly and SLA also showed that the highest correlation coefficient value occurs in the SON month in Semarang, Pekalongan, and Pemalang at 0.546202 - 0.676914.
Ideophonic patterns in Kiranti languages and beyond
Authors: Lahaussois Aimée 
Published: February 2023

AbstractThis article looks at descriptions of ideophones in Kiranti (Sino-Tibetan, Eastern Nepal) languages. It will do so by first providing a description of the ideophones of Thulung, for which four distinct ideophone types are identified, on the basis of a 10 h narrative corpus. Next, the results of this analysis will be compared to descriptions of ideophonic lexemes in sources on other Kiranti languages. In order to place these topics within an areal perspective, descriptions of the same phenomena in Nepali, the contact language for the linguistic area in question, will also be looked at. The goal of the article is to present data on the ideophonic patterns found in the Kiranti linguistic area and to consider the question of borrowing for ideophones in the Himalayas.
An open-label extension of a phase 2 dose-finding study of once-weekly somatrogon vs. once-daily Genotropin in children with short stature due to growth hormone deficiency: results following 5 years of treatment
Authors: Zadik Zvi , Zelinska Nataliya , Iotova Violeta , Skorodok Yulia , Malievsky Oleg , Mauras Nelly , Valluri Srinivas Rao , Pastrak Aleksandra , Rosenfeld Ron 
Published: February 2023

Abstract

Objectives
Somatrogon is a long-acting recombinant human growth hormone (GH) employed as a once-weekly treatment for children with GH deficiency (GHD). A 12-month, phase 2 study of once-weekly somatrogon vs. once-daily GH (Genotropin®) was initiated, after which participants could enroll into an open-label extension (OLE) evaluating the safety and efficacy of long-term somatrogon treatment.

Methods
There were five study periods, Periods I and II were 6 months each while Periods III, IV, and V were 12 months each. In the main study (Periods I and II), 53 prepubertal children with GHD were randomized to once-weekly somatrogon (0.25, 0.48, or 0.66 mg/kg/week) or once-daily Genotropin (0.034 mg/kg/day); 48 continued into the OLE, consisting of Period III (original somatrogon dose; Genotropin recipients randomized to one of three somatrogon doses), Period IV (somatrogon 0.66 mg/kg/week), and Period V (prefilled somatrogon pen [0.66 mg/kg/week]).

Results
At the end of Period III, the mean ± SD annual height velocity (HV) for 0.25, 0.48, and 0.66 mg/kg/week somatrogon groups was 7.73 ± 1.89, 7.54 ± 1.28, and 8.81 ± 1.12 cm/year, respectively; HV was sustained during Periods IV/V. Height SD scores (SDS) showed progressive improvement throughout the OLE, regardless of initial cohort assignment, approaching the normal range (−0.69 ± SD 0.87) at the end of Period V Year 1. Mild or moderate treatment-emergent adverse events were reported in 81.3% of participants, most unrelated to study drug.

Conclusions
Up to 5 years of once-weekly somatrogon was well tolerated and resulted in sustained improvement in height SDS and delta height SDS in prepubertal short children with GHD.
PEMBERDAYAAN BERBASIS PARIWISATA MELALUI HOMESTAY DI DESA WISATA BATULAYANG KECAMATAN CISARUA KABUPATEN BOGOR JAWA BARAT
Authors: Maulana Dimas Firli , Hermansah Tantan 
Published: February 2023

AbstractThere are various ways to empower oneself in the village. One of them is to make the need for community tourism a trigger for empowerment. By making some of the space in his house a place for tourists to stay, the residents of Batulayang Village make their house as a homestay. Through this homestay, villagers have become a tourist service business in the lodging sector, which then they mine profits that can help meet some of their needs. This study is based on the following research questions; (a) What is the process of homestay-based economic empowerment in Batulayang Tourism Village, and (b) How are the results of homestay-based economic empowerment in Batulayang Tourism Village. The results of the study show that the Batulayang tourism village homestay has tourism potential in economic empowerment by increasing people's income. The tourism-based economic empowerment process involves the active participation of the community which aims to create asustainable and independent tourist village.Keywords: community development; homestay; tourismAbstrakAda beragam cara memberdayakan diri di desa. Salah satunya adalah dengan menjadikan kebutuhan berwisata masyarakat sebagai pemantik pemberdayaan.Dengan menjadikan sebagian ruang di rumahnya untuk tempat menginap para wisatawan, warga Desa Batulayang menjadikan rumahnya sebagai homestay.Melaluihomestay ini, warga desa menjadi memiliki usaha jasa wisata di bidang penginapan, yang kemudian mereka menambang keuntungan yang bisa membantu memenuhi sebagian kebutuhannya.Studi ini didasarkan pada pertanyaan penelitian sebagai berikut; (a) Bagaimana proses pemberdayaan ekonomi berbasis homestay yang berada di Desa Wisata Batulayang, dan (b) Bagaimana hasil pemberdayaan ekonomi berbasis homestay di Desa Wisata Batulayang.Hasil dari penelitian menunjukkan bahwa homestayDesa Wisata Batulayang memiliki potensi pariwisata dalam pemberdayaan ekonomi dengan meningkatkan pendapatan masyarakat. Proses pemberdayaan ekonomi berbasis pariwisata pada dasarnya melibatkan peran partisipasi aktif masyarakat yang bertujuan untuk terciptanya desa wisata yang berkelanjutan dan mandiri.Kata kunci: pemberdayaan ekonomi; pariwisata; homestayDOI-
Remote Sensing of Primary Producers in the Bay-Delta
Authors:   University of California, Merced, Hestir Erin , Dronova Iryna ,   University of California, Berkeley
Published: February 2023

Remote-sensing methods are being used to study a growing number of issues in the San Francisco Estuary, such as (1) detecting the optical properties of chlorophyll-a concentrations and dissolved organic matter to assess productivity and the nature of carbon inputs, (2) creating historical records of invasive aquatic vegetation expansion through space and time, (3) identifying origins and expansions of invasions, and (4) supporting models of greenhouse-gas sequestration by expanding restoration projects. Technological capabilities of remote sensing have likewise expanded to include a wide array of opportunities: from boat-mounted sensors, human-operated low-flying planes, and aerial drones, to freely accessible satellite imagery. Growing interest in coordinating these monitoring methods in the name of collaboration and cost-efficiency has led to the creation of diverse expert teams such as the Remote Imagery Collaborative, and monitoring frameworks such as the Interagency Ecological Program Aquatic Vegetation Monitoring Framework and Wetland Regional Monitoring Program. This paper explores the emerging technologies and applications of various methods for studying primary producers, with an emphasis on remote sensing.
Cztery kategorie analogii i ich relacja do zagadnienia paradoksu w myśli Hansa Ursa von Balthasara
Authors: Wołowski Lech 
Published: February 2023

W artykule opisane zostały cztery kategorie analogii w refleksji Hansa Ursa von Balthasara: analogia entis, analogia fidei, analogia libertatis i analogia caritatis. Każda z tych kategorii została przeanalizowana w perspektywie towarzyszących jej paradoksów: paradoks jedności-wielości (nieudzielności-udzielności), paradoks universale concretum, paradoks wolności skończonej i nieskończonej, paradoks krzyża i zstąpienia do piekieł. Zasada analogii została tu skonfrontowana z metodą dostrzegania paradoksu i związanej z nim tajemnicy. Każde z zagadnień omówione zostało z uwzględnieniem źródeł myśli Balthasara (Anzelm, Przywara, Barth, de Lubac, von Speyr) i ze szczególnym uwzględnieniem jego oryginalnej refleksji. Pozwoliło to wyciągnąć wniosek dotyczący centralnego miejsca analogii miłości w koronnym dziele Balthasara, zwanym Trylogią.
Śmierć w dobie pandemii. Analiza przeżywania zjawiska śmierci w ujęciu egzystencjalizmu
Authors: Bańka Aleksander Ryszard 
Published: February 2023

Pandemia koronawirusa (COVID-19), która w 2020 roku rozlała się na cały świat, w bo-leśnie skonfrontowała współczesnego człowieka z doświadczeniem śmierci i straty. Zagrożenie własnego życia oraz odejście osób bliskich, pokonanych przez śmiertelną chorobę, dla wielu stało się wydarzeniem traumatycznym, które zmusza do ponowne-go postawienia pytania o sens życia i śmierci. Czy można zmierzyć się z tym pytaniem, przyjmując perspektywę filozoficznego egzystencjalizmu? To właśnie w ramach tego nurtu zrodziły się przecież dwa główne podejścia — ateistyczne i chrześcijańskie — pro-ponujące pewien sposób rozumienia kondycji człowieka dotkniętego dramatem śmierci. Niniejszy artykuł, opierając się na refleksji wybranych przedstawicieli obu kierunków i metodzie jej systematycznej analizy, stanowi próbę opisu egzystencjal-nej sytuacji człowieka czasów pandemii oraz odpowiedzi na pytanie, co doświadcze-nie śmierci może wnieść do jego sposobu rozumienia życia. W tym kontekście artykuł ukazuje wartość chrześcijańskiej koncepcji samoudzielenia się Boga w Chrystusie.
Pathogenicity of Human Anti-PLA2R1 Antibodies in Minipigs: A Pilot Study
Authors: Reinhard Linda , Wiech Thorsten , Reitmeier Aline , Lassé Moritz , Machalitza Maya , Heumann Asmus , Ferru Nicoletta , Loreth Desiree , Schröder Marie-Luise , Hutzfeldt Arvid , Stahl Felix R. , Peine Sven , Gröne Hermann-Josef , Meyer-Schwesinger Catherine , Rinschen Markus M. , Stahl Rolf A.K. , Hoxha Elion 
Published: February 2023

Significance Statement
Membranous nephropathy (MN) is an autoimmune kidney disease characterized by immune deposits in the glomerular basement membrane. Circulating anti-phospholipase A2 receptor 1 (PLA2R1) antibodies are detectable in 70%–80% of patients with MN, but experimental evidence of pathogenicity has been lacking. This study demonstrates the pathogenicity of human anti-PLA2R1 antibodies in minipigs, a model for MN that intrinsically expresses PLA2R1 on podocytes. After passive transfer of human anti-PLA2R1 antibody-containing plasma from patients with PLA2R1-associated MN to minipigs, antibodies were detected in the minipig glomeruli, but not in response to plasma from healthy controls. The minipigs developed histomorphological characteristics of MN, local complement activation in the glomeruli, and low-level proteinuria within 7 days, showing that human anti-PLA2R1 antibodies are pathogenic.

Background
Primary membranous nephropathy (MN) is an autoimmune kidney disease in which immune complexes are deposited beneath the epithelium in the glomeruli. The condition introduces a high risk for end-stage kidney disease. Seventy percent to 80% of patients with MN have circulating antibodies against phospholipase A2 receptor 1 (PLA2R1), and levels correlate with treatment response and prognosis. However, experimental evidence that human anti-PLA2R1 antibodies induce MN has been elusive.

Methods
In passive transfer experiments, minipigs received plasma or purified IgG from patients with PLA2R1-associated MN or from healthy controls. Anti-PLA2R1 antibodies and proteinuria were monitored using Western blot, ELISA, and Coomassie staining. Kidney tissues were analyzed using immunohistochemistry, immunofluorescence, electron microscopy, and proteomic analyses.

Results
Minipigs, like humans, express PLA2R1 on podocytes. Human anti-PLA2R1 antibodies bound to minipig PLA2R1 in vitro and in vivo. Passive transfer of human anti-PLA2R1 antibodies from patients with PLA2R1-associated MN to minipigs led to histological characteristics of human early-stage MN, activation of components of the complement cascade, and low levels of proteinuria. We observed development of an autologous, later phase of disease.

Conclusions
A translational approach from humans to minipigs showed that human anti-PLA2R1 antibodies are pathogenic in MN, although in the heterologous phase of disease only low-level proteinuria developed.
EFFECTS OF FACEBOOK ON EXAM PERFORMANCE OF SOCIAL SCIENCES STUDENTS: A CASE STUDY OF THE UNIVERSITY OF MALAKAND
Authors: Khan Asif Nawaz , Ali Sajjad , Amin Salman , Irfan Muhammad 
Published: February 2023

Purpose of the Study: As various researchers found, Facebook is one of the most popular social media platforms among students. The purpose of this study was to assess the effect of Facebook on students' exam performance.
Methodology: For this Study, data was collected from the regular students of BS social sciences at the University of Malakand. The researcher used quantitative methodology to obtain fruitful results. A questionnaire was designed to assess the effect of Facebook usage on students, and data was collected from 182 students' by simple random sampling technique. The analysis of the results was carried out through Statistical Package for Social Sciences (SPSS).
Main Findings: The Study found that the Usage of Facebook affects students' exam performance in Malakand. The study's results supported the hypothesis that the more the students used Facebook, their exam performance would be poor.
Application of the Study: This Study is essential to encourage students, parents and teachers to use Facebook for educational and learning purposes because most students use it for leisure time and relaxation. This study will help the students to manage Facebook usage time during exam days and to use it for refreshing and revealing boredom. It will help aware teachers and parents about the adverse effects of Facebook. The study will contribute a little to the existing literature gap on understanding the hurdle and blessing opportunities of Facebook in the exam environment.
The study's novelty: This is an exciting study involving university students and will discover the effects of Facebook on exam performance. The study will be helpful by bringing awareness among university students that Facebook Usage affects their exam performance. The study will also find out the relationship between Facebook usage and achievements in the exam. The students will come to know how spending more time on Facebook during exam days will affect their studies.
BIOCIDAL EFFECTS OF METABOLITES OF STREPTOMYCES GLOBISPORUS 3-1 AND STREPTOMYCES CYANOGENUS S136 STRAINS
Authors: Golembiovska S. L. , Polishchuk L. V. , Bambura O. I. 
Published: February 2023

Research of the biocide action of streptomycete-antagonist metabolites on the causative agent of bacterial canker of tomato and on the host-plant fertility is the actual question.
Aim. To determine the action of metabolites of Streptomyces globisporus 3-1 and Streptomyces cyanogenus S136 on the phytopathogen Clavibacter michiganensis 102 in vitro and on seed germination, growth and yield of tomatoes in vivo.
Methods. Microbiological methods in laboratory conditions and descriptive-comparative analysis of growth and development of tomatoes in hothouse conditions were used.
Results. S. globisporus 3-1 and S. cyanogenus S136 metabolites inhibited the growth of the phytopathogen C. michiganensis 102 with the formation of clean zones 45 and 35 mm in vitro, respectively. Pre-sowing treatment with metabolites of S. globisporus 3-1 and S. cyanogenus S136 of tomatoes Lana seeds reduced germination by 27% for both and led to defects in leaf shape and plant sterility, respectively. Treatment by metabolites of both Streptomyces strains of phytopathogen infected seeds did not improve germination, growth, and yield compared to grown plants from infected seeds, though it were visually not defective, sterile and with signs of bacterial canker of tomato.
Conclusion. It was found that metabolites of S. globisporus 3-1 and S. cyanogenus S136 had a biocide action on the phytopathogen C. michiganensis 102 in vitro and on Lana tomatoes in hothouse conditions.
Appraisal of E-Learning and students’ academic performance: A perspective from secondary schools
Authors: Olusegun Adebayo Adeokun , Uranta Elnathan , Ukhurebor Kingsley Eghonghon , Jokthan Grace , Nalwadda Dorothy 
Published: February 2023

This study investigated the effects of electronic learning (e-learning) on the academic performance (AP) of students in selected secondary (high) schools. A cross-sectional survey was used in this study to get data regarding students’ AP. The study was limited to three e-learning platforms (Zoom, WhatsApp, and Google Classroom) which were used by the participants in the survey during the COVID-19 pandemic-induced lockdown. A quantitative statistical analysis was carried out on the gathered data using SPSS. Analyses showed that e-learning had a negative effect on the attitudes of students. Furthermore, the analysis revealed that the e-learning systems were not as effective as traditional face-to-face teaching due to factors such as poor network connectivity and lack of collaborative activities. Furthermore, it was discovered that the e-learning materials were not widely available and accessible to the participants. Finally, suggestions that would guide further studies and improve student AP were also recommended.
Keywords: Academic performance, E-learning, Learning, Student, School
The impact of internet use on tertiary institution students’ academic performance: An exploratory study
Authors: Emeka Egbo Philip , Okoza Jolly , Ukhurebor Kingsley , Onwodi Gregory , Bayonle Fadayomi , Nyagblordjro Joshua 
Published: February 2023

This study investigates the impact of internet use on tertiary institution students’ academic performance (AP). The objectives of the study are to ascertain the impact of internet usage on the AP of students in tertiary institutions, find out some of the difficulties encountered in the utilization of the internet by students in tertiary institutions, and determine some of the benefits of internet usage to students in tertiary institutions. The sample size for this research consists of 300 students whose data were collected through the administration of questionnaires. The study employed the survey research method and the Chi-square (X2) method to analyse and test the various hypotheses formulated. Findings from the study show that there is a significant relationship between internet usage and the AP of students in tertiary institutions. Even though internet usage makes work faster and easier, there are various difficulties encountered in the utilization of the internet by students in tertiary institutions, and the study recommends some ways that will assist to mitigating these difficulties, as well as ways to improving internet use by tertiary institution students.
Keywords: Academic performance, Institution, Learning, Student, Teaching
Subacromial-Subdeltoid Bursitis With Rice Bodies After Rotator Cuff Repair With a Collagen Scaffold Implant
Authors: Root Kevin T. , Wright Jonathan O. , Mandato Nicholas , Stewart Brian D. , Moser Michael W. 
Published: February 2023

Case:
We report the second-known case of subacromial-subdeltoid bursitis with rice bodies after rotator cuff repair with a Smith + Nephew REGENETEN bovine-derived bioinductive collagen scaffold implant. After the removal of rice bodies and a portion of implant that had not incorporated, the patient recovered well and made a full return to work and recreational activities.

Conclusion:
This case demonstrates that persistent pain, swelling, or decreased range of motion for several months after rotator cuff repair with the use of a collagen implant may warrant a relatively early magnetic resonance imaging to evaluate for underlying pathology. It also provides a framework for physicians who may see similar patients in the future.