bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fabrication of new proton conducting membrane for fuel cell applications based on porous polyimide Matrimid® and hydrophobic protic ionic liquid
Authors: Rogalsky Sergiy , Tarasyuk Oksana , Babkina Natalia , Makhno Stanislav , Pertko Olexandra , Povazhnyi Volodymyr , Cherniavska Tetiana , Fatyeyeva Kateryna 
Published: February 2023

AbstractA new proton conducting membrane has been developed by impregnation of porous polyimide Matrimid® (PI) with hydrophobic protic ionic liquid triethylammonium bis(trifluoromethylsulfonyl)imide (TEA‐TFSI). According to the results of dynamic mechanical analysis (DMA), PI/TEA‐TFSI membrane has satisfactory viscoelastic properties in the temperature range 25–100°C. However, the sharp drop in storage modulus (E') occurs at higher temperatures that is probably caused by the plasticizing effect of ionic liquid. To improve the mechanical properties of PI matrix, it was impregnated with the solution of polyetheramine Jeffamine® D‐400 in the TEA‐TFSI. This approach allowed to obtain a partially cross‐linked PI which is more resistant to deformation at elevated temperatures. Thus, DMA study revealed a storage modulus around 400 MPa for PI/Jeffamine/TEA‐TFSI membrane up to 150°C, like neat porous Matrimid®. Thermogravimetric analysis results indicate high thermal stability of PI/Jeffamine/TEA‐TFSI composite with thermal degradation point of 343°C. The ionic conductivity of the composite membrane is 4·10−3 S/cm at room temperature and reaches the level of 10−2 S/cm above 100°C. Overall, the results of this study indicate that partially cross‐linked porous PI impregnated with hydrophobic protic ionic liquid is a promising polymer electrolyte membrane for fuel cells operating at elevated temperatures in water‐free conditions.
Bauphysikalische Untersuchungen an Myzel‐basierten Materialien für den Einsatz als Wärmedämmmaterial
Authors: Kotan Engin , Ibuk Attila , Dehn Frank 
Published: February 2023

AbstractUm die Verwendbarkeit von Materialien auf Pilzmyzel‐Basis als Baustoff bewerten zu können, wurden Versuche zu deren Eignung als Wärmedämmstoff durchgeführt. Hierzu wurden im Rahmen erster Tastversuche einem Basissubstrat verschiedene Zusätze (Buchenholz, Reisspelzen, Kaffee‐Silberhäutchen, Perlitgestein) beigemischt, um deren Einfluss auf bauphysikalische Materialeigenschaften zu ermitteln. Im Hinblick auf die Einsatzmöglichkeiten im Bauwesen hat sich gezeigt, dass Materialien auf Pilzmyzel‐Basis durchaus vielversprechende Eigenschaften aufweisen. Die erzielten Wärmeleitfähigkeiten sind mit denen von marktüblichen ökologischen Dämmstoffen konkurrenzfähig. Allerdings sind weitere, systematische Untersuchungen erforderlich, um die Möglichkeiten zur Optimierung der wesentlichen Materialeigenschaften zu erforschen und die Reproduzierbarkeit von Myzel‐Materialien mit möglichst homogenen Eigenschaften sicherstellen zu können.
Luminescence properties of Ce‐doped ZrO2 phosphors synthesized by combustion method
Authors: Lokesha H. S. , Nagabhushana K. R. , Tatumi S. H. , Rocca R. R. , Singh Fouran 
Published: February 2023

AbstractZr1−xCexO2 with x = 0.005, 0.01, 0.02, and 0.03 samples were synthesized using a combustion technique. The X‐ray diffraction results revealed that Ce‐doped ZrO2 nanoparticles were in a monoclinic structure up to 1 mol% Ce concentration. The increase in the Ce concentration caused more distortion in the monoclinic structure of zirconia. The samples showed a mixed phase (monoclinic + tetragonal) beyond 1 mol% Ce content. The crystallite size (D) and strain (ε) were calculated from the Williamson–Hall equation. The D decreased from 25 ± 1 to 20 ± 1 nm and ε increased from 0.03 to 0.28% with an increase in Ce concentration. Photoluminescence (PL) spectra of Zr1−xCexO2 showed emission in the blue region under an excitation wavelength of 290 nm. Zr0.995Ce0.005O2 showed the highest PL intensity with an average lifetime of 0.93 μs, and the PL intensity decreased with the increase in the Ce concentration. Thermoluminescence (TL) glow curves of Zr1−xCexO2 were measured after gamma irradiation (500 Gy) with a heating rate of 5 K s−1. The TL curve of Zr0.995Ce0.005O2 showed two prominent peaks at 412 K (peak 1) and 600 K (peak 2). The first TL glow peak was shifted towards a higher temperature at 440 K above 1 mol% Ce concentration. Repetitive TL measurements on the same aliquot exhibited excellent repeatability. Kinetic parameters associated with the TL peaks were calculated using the curve fitting method. Peak 1 followed non‐first‐order kinetics. The value of the activation energy of the 440 K peak was found to be 0.95 ± 0.01 eV for Zr0.99Ce0.01O2. These findings showed that Zr1−xCexO2 might be used in lighting and radiation dosimeter applications.
“That is just your stuff”: The potential use and abuse of congruence in counselling and psychotherapy practice and training
Authors: Jones Callum 
Published: February 2023

AbstractThis piece discusses the potential use and misuse of congruence within counselling training and practice. A definition of congruence is provided, and how deliberate misuse of congruence could result from two separate emotional communications (bullying and gaslighting) is discussed. Current representations and misrepresentations of congruence in counselling and psychotherapy have been highlighted. A new term of “Intentional Congruence Misuse” was coined to explain this position (not to be confused with incongruence). “Intentional Congruence Misuse” is the deliberate bullying of another individual using terms related to congruence. A discussion has been provided to emphasise the evident implications for counselling, psychotherapy practice and training. The author acknowledges that this opinion piece will be from a biased perspective. Still, it does not aim to detract from others who have found their therapy and counselling training beneficial.
SCAI stage reclassification at 24 h predicts outcome of cardiogenic shock: Insights from the Altshock‐2 Registry
Authors: Serrao Gregory , Dangas George 
Published: February 2023

Key points
SCAI Shock staging is dynamic and reclassification is expected to occur over time.
SCAI Shock classification at 24 hours is an independent predictor of in‐hospital mortality.
Further studies investigating the role of early invasive hemodynamic monitoring and mechanical circulatory support are still needed.
Utilization of TandemHeart in cardiogenic shock: Insights from the THEME registry
Authors: Megaly Michael , Gandolfo Chaun , Zakhour Samer , Jiang Mei , Burgess Kristie , Chetcuti Stanley , Ragosta Michael , Adler Eric , Coletti Andrew , O'Neill Brian , Alaswad Khaldoon , Basir Mir B. 
Published: February 2023

AbstractBackgroundTandemHeart has been demonstrated to improve hemodynamic and metabolic complications in cardiogenic shock (CS). Contemporary outcomes have not been reported.ObjectivesTo evaluate the outcomes of the TandemHeart (LivaNova) in contemporary real‐world use.MethodsWe analyzed baseline characteristics, hemodynamic changes, and outcomes of all patients treated with TandemHeart who were enrolled in the THEME registry, a multicenter, prospective, observational study.ResultsBetween May 2015 and June 2019, 50 patients underwent implantation of the TandemHeart device. 22% of patients had TandemHeart implanted within 12 h, 32% within 24 h, and 52% within 48 h of CS diagnosis. Cardiac index (CI) was significantly improved 24 h after implantation (median change 1.0, interquartile range (IQR) (0.5−1.4 L/min/m2). In survivors, there was a significant improvement in CI (1.0, IQR (0.5−2.25 L/min/m2) and lactate clearance −2.3 (−5.0 to −0.7 mmol/L). The 30‐day and 180‐day survival were 74% (95% confidence interval: 60%−85%) and 66% (95% confidence interval: 51%−79%), respectively. Survival was similarly high in those in whom TandemHeart has been used as a bridge to surgery (85% 180‐day survival).ConclusionIn a contemporary cohort of patients presenting in CS, the use of TandemHeart is associated with a 74% 30‐day survival and a 66% 180‐day survival.
Synthesis and Densification of Mo/Mg Co‐Doped Apatite‐type Lanthanum Silicate Electrolytes with Enhanced Ionic Conductivity
Authors: Li Jing , Cai Qiong , Horri Bahman Amini 
Published: February 2023

AbstractApatite‐type lanthanum silicate (LSO) electrolyte is one of the most promising candidates for developing intermediate‐temperature solid oxide electrolysis cells and solid oxide full cells (IT‐SOECs and SOFCs) due to its stability and low activation energy. However, the LSO electrolyte still suffers from unsatisfied ionic conductivity and low relative density. Herein, a new co‐doped method is reported to prepare highly purified polycrystalline powders of Mg−Mo co‐doped LSO (Mg/Mo‐LSO) electrolytes with high excellent densification properties and improved ionic conductivity. Introducing the Mo6+ and Mg2+ ions into the LSO structure can increase the number of interstitial oxide ions and improve the degree of densification at lower sintering temperatures, more importantly, expand the migration channel of oxide ions to enhance the ionic conductivity. As a result, the relative density of the fabricated Mo/Mg‐LSO electrolytes pellets could achieve more than 98 % of the theoretical density after sintering at 1500 °C for 4 h with a grain size of about 1–3 μm and the EIS results showed the ionic conductivity increased from 0.782 mS ⋅ cm−1 for the pristine LSO to 33.94 mS ⋅ cm−1 for the doped sample La9.5Si5.45Mg0.3Mo0.25O26+δ at 800 °C. In addition, the effect of different Mo6+ doping contents was investigated systematically, in which La9.5Si5.45Mg0.3Mo0.25O26+δ possessed the highest ionic conductivity and relative density. The proposed Mo/Mg co‐doped method in this work is one step forward in developing apatite‐structured electrolytes offering excellent potential to address the common issues associated with the fabrication of dense, highly conductive, and thermochemically stable electrolytes for solid oxide electrolysers and fuel cells.
Artificial neural network to predict the power number of agitated tanks fed by CFD simulations
Authors: Bibeau Valérie , Barbeau Lucka , Boffito Daria Camilla , Blais Bruno 
Published: February 2023

AbstractThe power consumption of the agitator is a critical variable to consider in the design of a mixing system. It is generally evaluated through a dimensionless number known as the power number . Multiple empirical equations exist to calculate the power number based on the Reynolds number and dimensionless geometrical variables that characterize the tank, the impeller, and the height of the fluid. However, correlations perform poorly outside of the conditions in which they were established. We create a rich database of 100 k computational fluid dynamics (CFD) simulations. We simulate paddle and pitched blade turbines in unbaffled tanks from 1 to 100 and use an artificial neural network (ANN) to create a robust and accurate predictor of the power number. We perform a mesh sensitivity analysis to verify the precision of the values given by the CFD simulations. To sample the 100 k mixers by their geometrical and physical properties, we use the Latin hypercube sampling (LHS) method. We then normalize the data with a MinMax transformation to put all features in the same scale and thus avoid bias during the ANN's training. Using a grid search cross‐validation, we find the best architecture of the ANN that prevents overfitting and underfitting. Finally, we quantify the performance of the ANN by extracting 30% of the database, predicting the using the ANN, and evaluating the mean absolute percentage error. The mean absolute error in the ANN prediction is 0.5%, and its accuracy surpasses correlations even for untrained geometries.
Hetero‐Polar Sextuple Bond: A Relativistic Quantum Chemical Study**
Authors: Kalita Amlan J. , Gohain Namrata , Bordoloi Abhik , Bania Kusum K. , Guha Ankur K. 
Published: February 2023

AbstractNumber of bonds formed by sharing an electron pair between two atoms is not restricted to one, it can go beyond four and six is the maximum. While homopolar sextuple bond in Mo2and W2has been reported, such a high bond order in heteropolar diatomics has remained elusive. In the pursuit of the sextuple bond in polar diatomics, the present study depicts the existence of such multiple bonds in Rhodium‐Scandium hetero‐diatom based on relativistic quantum chemical calculations. The bonding comprises of three normal electron sharing covalent bonds and three dative covalent bonds.
Comparative anticonvulsant activity of the GABAkine KRM‐II‐81 and a deuterated analog
Authors: Ping Xingjie , Meyer Michelle J. , Zahn Nicolas M. , Golani Lalit K. , Sharmin Dishary , Pandey Kamal P. , Revanian Sepideh , Mondal Prithu , Jin Xiaoming , Arnold Leggy A. , Cerne Rok , Cook James M. , Divović Branka , Savić Miroslav M. , Lippa Arnold , Smith Jodi L. , Witkin Jeffrey M. 
Published: February 2023

AbstractA series of imidazodiazepines has been developed that possess reduced sedative liabilities but retain efficacy in anticonvulsant screening models. The latest of these compounds, (5‐(8‐ethynyl‐6‐(pyridin‐2‐yl)‐4H‐benzo[f]imidazole[1,5‐α][1,4]diazepin‐3‐yl) oxazole known as KRM‐II‐81) is currently awaiting advancement into the clinic. A deuterated structural analog (D5‐KRM‐II‐81) was made as a potential backup compound and studied here in comparison to KRM‐II‐81. In the present study, both compounds significantly prevented seizures in mice induced by 6 Hz (44 mA) electrical stimulation without significantly altering motoric function on a rotarod after intraperitoneal administration. Both compounds also significantly prevented clonic seizures, tonic seizures, and lethality induced by pentylenetetrazol in mice when given orally. D5‐KRM‐II‐81 had a slightly longer duration of action against clonic and tonic seizures than KRM‐II‐81. Oral administration of 100 mg/kg of either KRM‐II‐81 or D5‐KRM‐II‐81 was significantly less disruptive of sensorimotor function in mice than diazepam (5 mg/kg, p.o.). The present report documents that D5‐KRM‐II‐81 represents another in this series of imidazodiazepines with anticonvulsant activity at doses that do not impair sensorimotor function.
Mobilising change in cities: A capacity framework for understanding urban energy transition pathways
Authors: Cheung Ting Ting Tracy , Fuller Sara , Oßenbrügge Jürgen 
Published: February 2023

AbstractThe role of cities in mobilising transformative change has gained increasing attention in global discourses on climate change and sustainability. Through the lens of urban energy transitions, this paper focuses on how this form of change within the urban energy system can be mobilised. Capacity is an emergent concept and has been adopted to identify areas for change and assess the transformative potential of cities. Connecting three dimensions of capacity: capacity for what, capacity of whom and the process of capacity building, we present a new conceptual framework to understand diverse transition pathways. To interrogate the capacity framework in practice, we explore the illustrative cases of Hamburg and Hong Kong. The paper demonstrates that capacity is connected to specific changes in political, material, institutional and other energy‐related societal contexts. Understanding the variety of dependencies and underlying challenges within urban energy systems , as well as the kinds of actor coalitions that are capable of addressing such complexity and mobilising change, enables the development of specific socio‐technical solutions for urban energy transition pathways. Our focus on local capacity to act and how such capacity can be expanded or diminished contributes to a deeper understanding of the power relations embedded in urban energy systems and the role local actors can play in enabling and hindering processes for change. Such examination of how complex trajectories for change are defined and shaped allows significant insights into plausible futures of urban development.
Signaling mechanisms in red blood cells: A view through the protein phosphorylation and deformability
Authors: Cilek Neslihan , Ugurel Elif , Goksel Evrim , Yalcin Ozlem 
Published: February 2023

AbstractIntracellular signaling mechanisms in red blood cells (RBCs) involve various protein kinases and phosphatases and enable rapid adaptive responses to hypoxia, metabolic requirements, oxidative stress, or shear stress by regulating the physiological properties of the cell. Protein phosphorylation is a ubiquitous mechanism for intracellular signal transduction, volume regulation, and cytoskeletal organization in RBCs. Spectrin‐based cytoskeleton connects integral membrane proteins, band 3 and glycophorin C to junctional proteins, ankyrin and Protein 4.1. Phosphorylation leads to a conformational change in the protein structure, weakening the interactions between proteins in the cytoskeletal network that confers a more flexible nature for the RBC membrane. The structural organization of the membrane and the cytoskeleton determines RBC deformability that allows cells to change their ability to deform under shear stress to pass through narrow capillaries. The shear stress sensing mechanisms and oxygenation‐deoxygenation transitions regulate cell volume and mechanical properties of the membrane through the activation of ion transporters and specific phosphorylation events mediated by signal transduction. In this review, we summarize the roles of Protein kinase C, cAMP‐Protein kinase A, cGMP‐nitric oxide, RhoGTPase, and MAP/ERK pathways in the modulation of RBC deformability in both healthy and disease states. We emphasize that targeting signaling elements may be a therapeutic strategy for the treatment of hemoglobinopathies or channelopathies. We expect the present review will provide additional insights into RBC responses to shear stress and hypoxia via signaling mechanisms and shed light on the current and novel treatment options for pathophysiological conditions.
The area‐reconstruction h‐dome technique and its efficient Python implementation for improved particle size image analysis
Authors: Geng Xiang , Liu Andong , Chen Yan'an , Meyers Greg 
Published: February 2023

AbstractThe traditional watershed segmentation methods usually suffer from over segmentation for irregularly shaped particles. This is because the distance map of an irregularly shaped particle contains multiple local maxima, and over segmentation would happen if these local maxima were used as seeds for watershed segmentation. In this work, several methods based on morphological reconstruction, including h‐dome transform, h‐maxima, and area‐reconstruction h‐dome transform, are introduced to merge, or erase redundant local maxima, and the performance of these methods in avoiding over segmentation is compared. The results show that the area‐reconstruction h‐dome transform is the most effective method in controlling over segmentation among the evaluated methods. However, the area‐reconstruction h‐dome transform is achieved by superposition of binary reconstructions at each grayscale level, which is extremely time‐consuming and impractical for batch processing. A hybrid pixel‐queue algorithm is applied to accelerate the area‐reconstruction h‐dome transform, and the algorithm is implemented in Cython to further improve the computational efficiency. For a 2592 × 1944 pixel image, on a PC with an Intel Core i5 2.4GHz processor and 8 GB RAM, the processing time of the area‐reconstruction h‐dome transform after acceleration is about 549 ms, which is 249 times faster than the unaccelerated algorithm and 4 times faster than the reconstruction function in the Scikit‐image library (an open‐source image processing library for the Python programming language) which performs reconstruction by dilation. The accelerated area‐reconstruction h‐dome transform algorithm was successfully applied to the segmentation of rubber particles in a thermoplastic polyolefin (TPO) compound.Research Highlights
Techniques for segmenting particles with irregular shapes based on morphological reconstruction are reviewed.
A fast algorithm for area‐reconstruction h‐dome transform is introduced based on Vincent's first approach combined with the pixel queue algorithm and Cython acceleration. The accelerated reconstruction algorithm is 249 times faster than the unaccelerated algorithm.
The fast area‐reconstruction h‐dome transform algorithm is successfully applied to rubber particle segmentation of a thermal plastic polyolefin.
Gaps in Depression Symptom Management for Patients With Head and Neck Cancer
Authors: Noel Christopher W. , Sutradhar Rinku , Chan Wing C. , Fu Rui , Philteos Justine , Forner David , Irish Jonathan C. , Vigod Simone , Isenberg‐Grzeda Elie , Coburn Natalie G. , Hallet Julie , Eskander Antoine 
Published: February 2023

ObjectiveTo understand practice patterns and identify care gaps within a large‐scale depression screening program for patients with head and neck cancer (HNC).Study DesignRetrospective cohort study.MethodsThis was a population‐based study of adults diagnosed with a HNC between January 2007 and October 2020. Each patient was observed from time of first symptom assessment until end of study date, or death. The exposure of interest was a positive depressive symptom screen on the Edmonton Symptom Assessment System (ESAS). Outcomes of interest included psychiatry/psychology assessment, social work referral, or palliative care assessment. Cause specific hazard models with a time‐varying exposure were used to investigate the exposure‐outcome relationships.ResultsOf 14,054 patients with HNC, 9016 (64.2%) reported depressive symptoms on at least one ESAS assessment. Within 60 days of first reporting depressive symptoms, 223 (2.7%) received a psychiatry assessment, 646 (7.9%) a social work referral, and 1131 (13.9%) a palliative care assessment. Rates of psychiatry/psychology assessment (HR 3.15 [95% CI 2.67–3.72]), social work referral (HR 1.83 [95% CI 1.64–2.02]), and palliative care assessment (HR 2.34 [95% CI 2.19–2.50]) were higher for those screening positive for depression. Certain patient populations were less likely to receive an assessment including the elderly, rural residents, and those without a prior psychiatric history.ConclusionA high proportion of head and neck patients report depressive symptoms, though this triggers a referral in a small number of cases. These data highlight areas for improvement in depression screening care pathways.Level of Evidence3 Laryngoscope, 133:2638–2646, 2023
Chimeric SCIP flap with iliac bone for reconstruction of foot first ray in a radiated surgical bed: A case report
Authors: Torrano Laura , Zamora Alarcón Paúl , Ibarra Andreé , Masiá Jaume , Sisternas Hernández Lucía , Fernández‐Garrido Manuel 
Published: February 2023

AbstractSurgical management of sarcoma has evolved from amputation to limb salvage. Nevertheless, subsequent resections in previously irradiated feet are still challenging to reconstruct. First foot ray functional reconstruction is relevant due to its function in weight‐bearing and gait. The reconstruction should include a thin, pliable and non‐shearing skin paddle with vascularized long cortical bone to mimic the first metatarsal. A clinical case of a 37‐year‐old patient with a second sarcoma recurrence of the first metatarsal is presented. The patient was irradiated before this new recurrence and had a previous reconstruction with fibula allograft, but subsequently developed a first metatarsal pseudoarthrosis. A wide resection was performed (3.5 cm bone defect) and immediate soft tissue and bone reconstruction with a chimeric SCIP flap with a 17 × 8 cm skin paddle and 3.5 × 1.5 cm iliac bone (cSCIP‐IB). At 7 months post‐operatively, the patient was able to resumed full weight‐bearing. Three years later, remains without disease progression. CSCIP‐IB is a good option for foot first ray reconstruction in irradiated beds. This flap has low donor site morbidity and a higher ossification success rate compared to bone allografts.