bluuebunny/crossref_metadata_2025_split huggingface dataset:
The efficacy and safety of complementary and alternative medicine in the treatment of nausea and vomiting during pregnancy: A systematic review and meta-analysis
Authors: Tan Mo-Yao , Shu Shi-Hong , Liu Run-Lei , Zhao Qian 
Published: March 2023

BackgroundComplementary and alternative medicine (CAM) therapies are widely used for nausea and vomiting during pregnancy (NVP) due to the limitations of conventional medicine. However, their efficacy and safety remain controversial. Therefore, this meta-analysis was performed to assess the improvement of CAM therapy on NVP.MethodsRandomized controlled trials (RCTs) were searched for where the trial group was CAM and the control group was a conventional medicine or a placebo for NVP. This was done via 8 databases, including PubMed, EMBASE, the Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, SinoMed, and VIP, from inception to October 25, 2022. The Grades of Recommendation, Assessment, Development and Evaluation (GRADE) was used to assess the quality of evidence. The Stata 15.0 software was used to perform the meta-analysis.ResultsThirty-three RCTs were included in this study. The acupuncture treatment was superior to conventional medicine at the effective rate [RR = 1.71, 95% CI (1.02, 2.86), P = 0.042; Low-quality evidence]. Ginger had more significant effects than conventional medicine at the Rhodes index [WMD = −0.52, 95% CI (−0.79, −0.24), P ≤ 0.001; Moderate-quality evidence] and it had the same effect as drugs to relieve vomiting [SMD = 0.30, 95% CI (−0.12, 0.73), P = 0.160; Low-quality evidence]. Compared with placebo, ginger had a higher effective rate [RR = 1.68, 95% CI (1.09, 2.57), P = 0.018; Low-quality evidence], and lower Visual analog scale (VAS) of Nausea [WMD = −1.21, 95% CI (−2.34, −0.08), P = 0.036; Low-quality evidence]. Ginger had the same antiemetic effect as placebo [WMD = 0.05, 95% CI (−0.23, 0.32), P = 0.743; Low-quality evidence]. Acupressure was superior to conventional medicine at the reduction of antiemetic drugs [SMD = −0.44, 95% CI (−0.77, −0.11), P = 0.008; Low-quality evidence], and at the effective rate [RR = 1.55, 95% CI (1.30, 1.86), P ≤ 0.001; Low-quality evidence]. Acupressure had the same effect as placebo at the effective rate [RR = 1.25, 95% CI (0.94, 1.65), P = 0.124; Low-quality evidence]. Overall, CAM therapy was safer than conventional medicine or a placebo.ConclusionThe results showed that CAM therapies were able to alleviate NVP. However, due to the low quality of existing RCTs, more RCTs with large sample sizes are needed to validate this conclusion in the future.
Characterization of interventional clinical trials for monkeypox; systematic review of ClinicalTrials.gov database
Authors: Alorfi Nasser M. , Alshehri Fahad S. , Haseeb Abdul 
Published: March 2023

BackgroundMonkeypox (mpox), a zoonotic viral infection, poses a global threat that is being acknowledged at the national and international levels. This systematic review aims to identify and characterize interventional clinical trials for mpox.MethodAll interventional clinical trials registered at ClinicalTrials.gov for mpox were searched up to January 6, 2023. We described the characteristics of interventional clinical trials, and drug interventions (including drugs and vaccines).ResultsAs of January 6, 2023, there were 10 clinical trials in the ClinicalTrials.gov registry that met our criteria. Most of the interventional clinical trials were focused on the treatment (N = 4, 40%) and prevention (N = 4, 40%) of mpox. From the 10 trials, 50% used random treatment allocation, and six (60%) chose the parallel assignment intervention model. All 10 studies were blinded, and six were open-label blinded. The largest proportion of the clinical trials (N = 4, 40%) were registered in Europe, followed by America (N = 3, 30%) and Africa and others (N = 3, 30%). The JYNNEOS vaccine (40%), followed by Tecovirimat (30%) were the most frequently studied drugs used against mpox.ConclusionA limited number of clinical trials have been registered on ClinicalTrials.gov since the first case of mpox was reported. Therefore, there is an urgent need to conduct large-scale randomized clinical trials to assess the safety and efficacy of the drugs and vaccines being used against the mpox virus.
The medium-term perceived impact of work from home on life and work domains of knowledge workers during COVID-19 pandemic: A survey at the National Research Council of Italy
Authors: Bodini Antonella , Leo Carlo Giacomo , Rissotto Antonella , Mincarone Pierpaolo , Fusco Stanislao , Garbarino Sergio , Guarino Roberto , Sabina Saverio , Scoditti Egeria , Tumolo Maria Rosaria , Ponzini Giuseppe 
Published: March 2023

ObjectiveThe study aimed to investigate perceptions and determinants of the overall impact on life and work domains among a community of knowledge workers after 18 months of forced work from home due to the pandemic.MethodsA cross-sectional study with a retrospective assessment was conducted early in 2022 at the National Research Council of Italy. Five single-item questions explored the perceived impact on life domain while a 7-item scale the impact on the work domain. Bivariate analyses and multivariate regressions were used to evaluate the associations between impacts and some key factors defined by 29 ad hoc closed questions.ResultsMore than 95% of the 748 respondents reported a perceived change in at least one item of the life domain. For each of these items, although a large group of subjects has reported that working from home had no impact (from 27 to 55%), in the rest of the sample the positive evaluation (from 30 to 60%) clearly prevailed over the negative one. Overall, most of the subjects (64%) rated the impact on the work experience positively. Relationship with colleagues and participation in the work context were the items where the greatest number of negative rates was concentrated (27 and 25%, respectively). On the other hand, positive perceptions prevailed over both negative perceptions and lack of impact perceptions on the subjects of organizational flexibility and quality of work. The frequency of work-room sharing, home-work commute time and changes in sedentary lifestyle, have been identified as common explanatory factors of perceived impacts on both domains.ConclusionOverall, respondents reported positive rather than negative perceived impacts of forced work from home in both their lives and work. The obtained results suggest that policies to promote the physical and mental health of employees, strengthen inclusion and maintain a sense of community are necessary to improve workers' health and prevent the effects of perceived isolation on research activities.
Effects of dietary camelina, flaxseed, and canola oil supplementation on inflammatory and oxidative markers, transepidermal water loss, and coat quality in healthy adult dogs
Authors: Richards Taylor L. , Burron Scarlett , Ma David W. L. , Pearson Wendy , Trevizan Luciano , Minikhiem Debbie , Grant Caitlin , Patterson Keely , Shoveller Anna K. 
Published: March 2023

IntroductionCamelina oil contains a greater concentration of omega-3 (n-3) a-linolenic acid (C18:3n-3; ALA) than omega-6 (n-6) linoleic acid (C18:2n-6; LA), in comparison to alternative fat sources commonly used to formulate canine diets. Omega-3 FAs are frequently used to support canine skin and coat health claims and reduce inflammation and oxidative stress; however, there is a lack of research investigating camelina oil supplementation and its effects on these applications in dogs. The objective of this study was to evaluate the effects of camelina oil supplementation on coat quality, skin barrier function, and circulating inflammatory and oxidative marker concentrations.MethodsThirty healthy [17 females; 13 males; 7.2 ± 3.1 years old; 27.4 ± 14.0 kg body weight (BW)] privately-owned dogs of various breeds were used. After a 4-week wash-in period consuming sunflower oil (n6:n3 = 1:0) and a commercial kibble, dogs were blocked by age, breed, and size, and randomly assigned to one of three treatment oils: camelina (n6:n3 = 1:1.18), canola (n6:n3 = 1:0.59), flaxseed (n6:n3 = 1:4.19) (inclusion level: 8.2 g oil/100 g of total food intake) in a randomized complete block design. Transepidermal water loss (TEWL) was measured using a VapoMeter on the pinna, paw pad, and inner leg. Fasted blood samples were collected to measure serum inflammatory and oxidative marker concentrations using enzyme-linked immunosorbent assay (ELISA) kits and spectrophotometric assays. A 5-point-Likert scale was used to assess coat characteristics. All data were collected on weeks 0, 2, 4, 10, and 16 and analyzed using PROC GLIMMIX in SAS.ResultsNo significant changes occurred in TEWL, or inflammatory and oxidative marker concentrations among treatments, across weeks, or for treatment by week interactions. Softness, shine, softness uniformity, color intensity, and follicle density of the coat increased from baseline in all treatment groups (P &lt; 0.05).DiscussionOutcomes did not differ (P &gt; 0.05) among treatment groups over 16-weeks, indicating that camelina oil is comparable to existing plant-based canine oil supplements, flaxseed, and canola, at supporting skin and coat health and inflammation in dogs. Future research employing an immune or exercise challenge is warranted, as the dogs in this study were not subjected to either.
Increased IL-17A Serum Levels and Gastric Th17 Cells in Helicobacter pylori-Infected Patients with Gastric Premalignant Lesions
Authors: Della Bella Chiara , D’Elios Sofia , Coletta Sara , Benagiano Marisa , Azzurri Annalisa , Cianchi Fabio , de Bernard Marina , D’Elios Mario Milco 
Published: March 2023

Background: Helicobacter pylori infection is characterized by an inflammatory infiltrate that might be an important antecedent of gastric cancer. The purpose of this study was to evaluate whether interleukin (IL)-17 inflammation is elicited by gastric T cells in Helicobacter pylori patients with gastric intestinal metaplasia and dysplasia (IM/DYS). We also investigated the serum IL-17A levels in Helicobacter pylori patients with gastric intestinal metaplasia and dysplasia, and patients with Helicobacter pylori non-atrophic gastritis (NAG). Methods: the IL-17 cytokine profile of gastric T cells was investigated in six patients with IM/DYS and Helicobacter pylori infection. Serum IL-17A levels were measured in 45 Helicobacter pylori-infected IM/DYS patients, 45 Helicobacter pylori-infected patients without IM/DYS and in 45 healthy controls (HC). Results: gastric T cells from all IM/DYS patients with Helicobacter pylori were able to proliferate in response to Helicobacter pylori and to produce IL-17A. The Luminex analysis revealed that IL-17A levels were significantly increased in Helicobacter pylori IM/DYS patients compared to healthy controls and to Helicobacter pylori gastritis patients without IM/DYS (452.34 ± 369.13 pg/mL, 246.82 ± 156.06 pg/mL, 169.26 ± 73.82 pg/mL, respectively; p < 0.01, p < 0.05). Conclusions: the results obtained indicate that Helicobacter pylori is able to drive gastric IL-17 inflammation in IM/DYS Helicobacter pylori-infected patients, and that IL-17A serum levels are significantly increased in Helicobacter pylori-infected patients with IM/DYS.
Major Emerging Fungal Diseases of Reptiles and Amphibians
Authors: Schilliger Lionel , Paillusseau Clément , François Camille , Bonwitt Jesse 
Published: March 2023

Emerging infectious diseases (EIDs) are caused by pathogens that have undergone recent changes in terms of geographic spread, increasing incidence, or expanding host range. In this narrative review, we describe three important fungal EIDs with keratin trophism that are relevant to reptile and amphibian conservation and veterinary practice. Nannizziopsis spp. have been mainly described in saurians; infection results in thickened, discolored skin crusting, with eventual progression to deep tissues. Previously only reported in captive populations, it was first described in wild animals in Australia in 2020. Ophidiomyces ophidiicola (formely O. ophiodiicola) is only known to infect snakes; clinical signs include ulcerating lesions in the cranial, ventral, and pericloacal regions. It has been associated with mortality events in wild populations in North America. Batrachochytrium spp. cause ulceration, hyperkeratosis, and erythema in amphibians. They are a major cause of catastrophic amphibian declines worldwide. In general, infection and clinical course are determined by host-related characteristics (e.g., nutritional, metabolic, and immune status), pathogens (e.g., virulence and environmental survival), and environment (e.g., temperature, hygrometry, and water quality). The animal trade is thought to be an important cause of worldwide spread, with global modifications in temperature, hygrometry, and water quality further affecting fungal pathogenicity and host immune response.
La comunidad marginal: Un enfoque con preferencia al caso cubano
Authors: Villalva Heredia Carlos Iván , Cruz Betancourt Raquel 
Published: March 2023

El presente artículo tiene como objetivo, evaluar el fenómeno de la marginalidad económica y social con un enfoque que prioriza el caso cubano. Se analiza la marginalidad desde la perspectiva económica y cultural. Se analizan variedad de percepciones y aspectos de la marginalidad, sobre todo, los que hacen de esta una identificación con la exclusión y la subcultura. También se presenta una descripción de los tipos de comunidades marginales en Cuba, así como argumentos que demuestran el derecho a la participación política y social en Cuba, cosa que aleja a la comunidad marginal cubana de la exclusión social. Esto permitió una nueva percepción sobre marginalidad cuando se aplican proyectos de vida que permiten paliar las dificultades económicas, sociales y culturales que el fenómeno de la marginalidad implica.
CALCULATION OF FORCES ON THE PROPULSION AND STEERING COMPLEX WHEN MODELING SEA TOWING ON THE EXAMPLE OF THE TANKER «ARKHANGELSK»
Authors: Ischeykin G. 
Published: March 2023

For modeling sea towing, it is required to enter parameters into the mathematical model of the vessel that
determine the influence of both external and internal factors. This article presents the calculation of the forces
on the propulsion and steering complex on the example of the tanker «Arkhangelsk». The calculation results
and fragments of the program in the MathCad computing environment clearly represent the changes in the
parameters of the propulsion and steering complex during the movement of the tanker. The presented software
calculation methods can also be used when conducting model experiments with models of various types of
vessels
REDUCING CARBON DIOXIDE EMISSIONS FROM MARINE DIESEL ENGINES BY OPTIMIZING FUEL SUPPLY AND COMBUSTION
Authors: Ignatenko G. , Turkin V. , Sviderskaya O. , Belyaev V. , Zubko S. 
Published: March 2023

The simulation of the working processes of the MAN D&T MC series marine diesel engine was carried out in
order to reduce carbon dioxide emissions with exhaust gases. The purpose of the simulation was to find design
and operational solutions that affect CO2 emissions. When performing a computational study, a mathematical
model of a combined internal combustion engine implemented in the DIESEL-RK computer program was used. The studied variables are the compression ratio, the advance angle and the duration of fuel injection, the values
of which can be set without making significant changes to the engine design. Mathematical models are obtained
in the form of regression equations that describe the effect of the studied fuel supply parameters (compression
ratio, fuel injection advance angle and fuel injection duration) on the target functions - specific carbon dioxide
emission and effective power of the 6S60MC diesel engine. To determine the coefficients of the regression
equation, planning of a complete factorial experiment of the second order is implemented. In order to find the
minimum value of carbon dioxide emissions using the generalized reduced gradient method, the problem of
choosing the optimal values of the compression ratio, fuel injection duration and fuel injection advance angle
for a given effective power of a 6S60MC marine diesel engine is solved. It is shown that, for example, with an
engine power of 10,000 kW, the reduction in carbon dioxide emissions by optimizing the specified fuel supply
parameters will be 7.37%
SHIP SYSTEM FOR CLEANING ENGINE EXHAUST GASES FROM CARBON, SULFUR AND NITROGEN OXIDES
Authors: Ignatenko G. , Turkin Vladimir Antonovich , Belyaev V. , Sviderskaya O. , Zubko S. 
Published: March 2023

To clean the exhaust gases of engines from carbon, nitrogen and sulfur oxides, a method and device are proposed,
the principle of which is based on the fact that the exhaust gases pass through an absorber, where they
are cleaned of nitrogen and sulfur oxides, and then through adsorption sections filled with granules of slag
pumice and are purified from carbon oxides as a result of their adsorption. Carbon dioxide, interacting with
water particles in the pores of the granules, forms carbonic acid. Then the diluted carbonic acid condensate
after cleaning in the separator from solid impurities is discharged overboard. The composition of a shipboard
system for continuous laser monitoring and control of emissions of carbon, nitrogen and sulfur oxides contained
in the exhaust gases of engines by adjusting their adjustment parameters, as well as using a device for complex
exhaust gas purification, is proposed. An algorithm for solving the problem of fulfilling the requirements of
regulation 20 "Achievable EEDI" of Appendix VI of the MARPOL 73/78 Convention on carbon oxide emissions
has been developed. The implementation of the proposed algorithm is possible using a system for cleaning
combustion products from harmful oxides
DEVICE FOR MONITORING ADDITIONAL LOSSES OF A SHIP TRANSFORMER BASED ON A TEMPERATURE MODEL
Authors: Grinek A , Boychuk Igor , Tinyakov D. , Marchenko N. , Aleksyanc S. , Slonov E. 
Published: March 2023

The article considers a way to improve the efficiency of ship transformers. A temperature control system is
used. In the process of changing the voltage in the ship's system, thermal losses of copper in the iron core and
coil usually often occur. Thus, overloading will cause excessive heating and may affect the operation of the
transformer. The calculation of the thermal parameters of the transformer is given. The mathematical model in
Matlab is shown. The article proposes a functional diagram of the device. The control system monitors the
temperature inside the transformer when operating under overload conditions. It is shown that the installation
of the device will improve the performance o f the transformer and save its service life
ANALYSIS OF MANAGEMENT AND ADMINISTRATION TOOLS LINUX AND WINDOWS OPERATING SYSTEMS
Authors: Al'-Hanani M. , Sokolova I. , Puchkov A. 
Published: March 2023

In this scientific article, the market research o f modern management and administration tools o f the Linux and
Windows OS family is carried out, a comparative analysis o f the most popular and demanded o f them is carried
out. The basic requirements for management and administration tools are formulated, their main features are
highlighted.
To date, there are many OS management and administration tools. Each o f them has its advantages and disadvantages.
Therefore, it is sometimes very difficult to choose the right tool
APPLICATION OF ARTIFICIAL NEURAL NETWORK APPARATUS FOR SECURINGNAVIGATIONAL AND ECOLOGICAL SAFETY IN COMPLICATED DYNAMIC SITUATION
Authors: Borodin E , Bidenko S , Bengert A. , Muchkaeva I. , Kirilenko A , Hramov I. , Bidenko S. 
Published: March 2023

Particulars o f factors o f navigational and ecological safety on the example o f the Obb Bay when sailing in areas
with the situation quickly changed. Apparatus o f artificial neural networks for operational situation appraisal
in the nearest marine ship's zone has been suggested. Basic types o f neural network architecture suitable for
analysis o f dynamic territorial situation has been also advised. Comparison o f artificial neural structure on
parameter o f fast acting and exactness applicable for the task o f situation appraisal has been made. It shows the
advantage o f recurrent neural network
Advances in and Issues With Minimally Invasive Surgery for Rectal Cancer in Elderly Patients
Authors: Shiraliev R. M.-A. , Polovinkin V. V. , Murashko R. A. , Kaushanskiy V. B. , Doronin N. V. , Gumenyuk S. E. 
Published: March 2023

Colorectal cancer ranks third after breast cancer in terms of incidence and second after lung cancer in terms of mortality.Management of rectal cancer requires a multidisciplinary approach, with the surgical management playing the main role. There are currently three resective techniques that complement the traditional open surgery: laparoscopic surgery, robotic surgery, and transanal total mesorectal excision.Rectal cancer in elderly patients is particularly hard to diagnose and treat surgically due to multiple comorbidities and limited functional reserve. Treatment of such patients may be associated with poorer outcomes after both open and minimally invasive surgery.This article reviews the current state of advances in minimally invasive surgery for rectal cancer in general and in elderly patients in particular.
Can We Detect Peritoneal Adhesions With MRI and CT Prior to Abdominal Surgery?
Authors: Armashov V. P. , Belousov A. M. , Vavshko M. V. , Gorskiy V. A. , Pavlenko V. V. , Matveev N. L. 
Published: March 2023

This article is part 2 of our review assessing diagnostic modalities. In the first part, we analyzed the ultrasonography capabilities to detect abdominal adhesions. The second part assesses the effectiveness of MRI and CT.MRI and CT modalities are much less commonly used in detecting adhesions than ultrasonography. MRI has approximately the same prognostic capabilities as ultrasonography in detecting adhesions between the viscera and the abdominal wall, and it additionally detects adhesions between the abdominal organs. Yet, MRI is significantly more time-consuming and highly dependent on the radiologist experience. Like ultrasonography, MRI determines the extent of adhesions but not the type.Native CT does not visualize abdominal adhesions, though its findings in artificial pneumoperitoneum are superior in diagnostic value to those of ultrasonography and MRI, so this modality should be considered.
Impact of the split-off band on the tunneling current at metal/heavily-doped p-type SiC Schottky interfaces
Authors: Kitawaki Takeaki , Hara Masahiro , Tanaka Hajime , Kaneko Mitsuaki , Kimoto Tsunenobu 
Published: March 2023

Abstract
Ni/p-type SiC Schottky barrier diodes with various acceptor densities (N
A = 5 × 1015 to 3 × 1019 cm−3) are fabricated and the measured current–voltage characteristics are analyzed by numerical calculation of tunneling current. The tunneling current is calculated taking account of multiple valence bands. It is revealed that tunneling of holes in the split-off band, which has a light effective mass (0.21m
0), is the dominant conduction mechanism at metal/heavily-doped p-type SiC Schottky interfaces.
ЗАЛЕЖНІСТЬ КОЕФІЦІЄНТА ВИТРАТИ ВІД ДІАМЕТРА ПРОХІДНОГО ОТВОРУ ГОДИННИКОВИХ КАМЕНІВ ЯК ЗВУЖУВАЛЬНИХ ПРИСТРОЇВ ГАЗОДИНАМІЧНИХ МІКРОВИТРАТОМІРІВ ГАЗУ
Authors: Стасюк І. Д.  , Ділай І. В.  , Брилинський Р. Б.  
Published: March 2023

У роботі на основі опрацювання та аналізу експериментально визначених значень коефіцієнта витрати α годинникових каменів з різними діаметрами d їхнього прохідного отвору отримано аналітичну залежність між коефіцієнтом α та значенням діаметра d годинникових каменів. Отримана залежність забезпечує спрощення процедури визначення коефіцієнта витрати α годинникових каменів як звужувальних пристроїв газодинамічних витратомірів та дає можливість з високою точністю за відомим значенням діаметра d прохідного отвору конкретного годинникового каменя обчислювати значення його коефіцієнта α. Відхилення обчисленого значення коефіцієнта витрати α від експериментально визначеного не перевищує 0,45 %.