bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assist-linked brief intervention to reduce risky pattern of substance use in male workers employed at a tertiary care hospital in India: A randomized controlled trial
Authors: Prasad Sambhu , Basu Debasish , Mattoo Surendra K. , Subodh B. N 
Published: January 2023

ABSTRACT

Background:
Substance use in workplace leads to adverse effects both on the employees and on the workplace. Existing research focuses on alcohol-related harm, while workplace use of other substances has been neglected. There are no randomized controlled studies of brief interventions in Indian hospital settings.

Aim:
To evaluate the efficacy of World Health Organization (WHO) alcohol, smoking, and substance involvement screening test (ASSIST)-linked brief intervention (ALBI) for reducing risky patterns of substance use in male workers at a tertiary-care hospital in North India.

Material and Methods:
The study was conducted in two phases. In Phase-I, a random list of 400 employees was generated from the entire pool of male hospital workers, of which 360 participated. Data on the ASSIST risk categories (mild, moderate, and high) were generated from Phase I. In Phase-II, moderate- or high-risk subjects (‘ASSIST screen-positive’) were randomized into intervention and control groups, with 35 screen-positive subjects in each group. The intervention group was provided a 15–30-min structured session per ALBI protocol, while the control group was given a 15–30-min general talk on health-related consequences associated with substance use. The subjects were compared on ASSIST score, WHO quality-of-life brief version (WHOQOL-BREF) and readiness to change questionnaire (RCQ) at baseline and at 3-month follow up.

Results:
The prevalence of moderate-to-high-risk use of tobacco, alcohol, and cannabis in the total sample was 28.6%, 27.5%, and 6.9%, respectively. At 3-months postintervention follow-up of the randomized sample, recipients of ALBI had significant reduction of ASSIST scores for all substances compared to the control group (p < 0.001). More participants receiving ALBI were ready to change to RCQ action stage (p values for tobacco, alcohol, and cannabis <0.001, <0.001 and 0.007, respectively). WHOQOL-BREF scores significantly improved in ALBI group across all domains.

Conclusion:
ALBI was effective in reducing risky substance use, increasing readiness to change and improving the QOL of the subjects at workplace setting.
Relationship between serum lipids and depression: A cross sectional survey among adults in Haryana, India
Authors: Mulchandani Rubina , Lyngdoh Tanica , Nangia Ria , Singh Sukriti , Grover Sandeep , Thakur JS 
Published: January 2023

ABSTRACT

Introduction:
Dyslipidemia and mental illnesses are significant contributors to the global noncommunicable disease burden and studies suggest an association between them.

Aim:
Using data from a noncommunicable disease risk factor survey conducted in Haryana, India, we undertook a secondary data analysis to examine the association between lipids and depressive symptoms.

Methods:
The survey involved 5,078 participants and followed the World Health Organisation STEPwise approach to NCD risk factor surveillance approach. Biochemical assessments were undertaken in a subset of participants. Lipid markers were measured using wet chemistry methods. Depressive symptoms were assessed using the Patient Health Questionnaire–9. Descriptive statistics were presented for all variables; logistic regression was used for association analyses.

Results:
The mean age of the study population was 38 years and 55% of them were females. A majority of the participants belonged to a rural background. The mean total cholesterol was 176 mg/dL and approximately 5% of the participants were found to have moderate to severe depression. The association of total cholesterol (odds ratio [OR] 0.99, P = 0.84), LDL-cholesterol (OR = 1.00, P = 0.19), HDL-cholesterol (OR = 0.99, P = .76), and triglycerides (OR 1.00, P = .12) with depressive symptoms was not significant.

Conclusion:
This study did not find any association between lipids and depressive symptoms. However, further investigations using prospective designs are warranted to understand this relationship and complex interactions with other mediating factors better.
Analysis of risk factors related to acute radiation dermatitis in breast cancer patients during radiotherapy
Authors: Liu Di , Zheng Zhewen , Zhang Shuyuan , Zhu Chunmei , Zhang Hongyan , Zhou Yunfeng 
Published: January 2023

Aims:
To investigate the incidence and influencing factors of acute radiation dermatitis (ARD) induced by radiotherapy in postoperative patients with breast cancer.

Methods and Materials:
A retrospective analysis was conducted on 598 patients with breast cancer who received postoperative radiotherapy from November 18, 2014 to September 14, 2019. The radiotherapy technology included two-dimensional radiotherapy, three-dimensional conformal radiotherapy, intensity-modulated radiotherapy, and tomotherapy. The occurrence of ARD in patients was then followed up and recorded. The independent risk factors for radiation-induced dermatitis were analyzed by using an orderly logistic regression model.

Results:
Of the 598 patients, 431 had mild skin reactions, including pigmentation and dry desquamation (grade 1), 151 developed wet desquamation and tender erythema (grade 2), and 16 had severe skin reactions, including flaky wet scaling and erosion (grade 3). There were no grade 4 skin reactions. The severity of ARD was independent of the following factors: Age, diabetes, allergy, quadrant, pathological type, the clinical stage, the tumor stage, triple-negative breast cancer, ki-67 expression, adjuvant chemotherapy, endocrine therapy, targeted therapy, radiotherapy area, and boost irradiation. However, it was found to be dependent on the body mass index, surgery type, radiotherapy technique, node stage, and the prophylactic use of topical agents.

Conclusions:
ARD in response to postoperative radiotherapy in patients with breast cancer is common and mild. Clinicians and patients need to cultivate awareness of the potential risk factors involved and then intervene to alleviate skin reactions and improve the quality of life.
CASP4 and CASP8 as newly defined autophagy-pyroptosis-related genes associated with clinical and prognostic features of renal cell carcinoma
Authors: Li Tao , Liu Ning , Zhang Guangyuan , Chen Ming 
Published: January 2023

Objective:
The rapid discoveries of autophagy and pyroptosis have opened new avenues for treating renal cell carcinoma (RCC). The objective was to identify potential autophagy-pyroptosis-related drug targets and plausible prognostic biomarkers crucial for disease detection.

Materials and Methods:
Gene expression data were downloaded from Gene Expression Omnibus (GSE168845), and autophagy-pyroptosis-related differentially expressed genes (DEGs) were identified. The prognostic values of DEGs were assessed using differential expression analysis and Kaplan–Meier curves, a prognostic nomogram was constructed using the DEG data, and the correlation between DEGs and infiltrating immune cells was evaluated. Additionally, quantitative real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry (IHC) were carried out to verify the expression levels of DEGs.

Results:
CASP4 and CASP8 were identified as RCC-associated autophagy-pyroptosis-related genes, and CASP4 and CASP8 were found to be highly expressed in RCC tumor tissues. High expression of CASP4 and CASP8 was associated with higher pathological staging and poorer prognosis, whereas a prognostic nomogram constructed based on CASP4 and CASP8 could better predict RCC patient survival rates. Additionally, increased expression of CASP4 and CASP8 was highly correlated with the expression levels of multiple infiltrating immune cell types. Moreover, qRT-PCR and IHC validated the increased expression of CASP4 and CASP8 in RCC.

Conclusion:
CASP4 and CASP8 were autophagy-pyroptosis-related genes associated with immunotherapy in RCC. CASP4 and CASP8 were identified as potential targets and effective prognostic biomarkers for RCC.
Serological indices and ultrasound variables in predicting the staging of hepatitis B liver fibrosis
Authors: Xie Daolin , Ying Minghua , Lian Jingru , Li Xin , Liu Fangyi , Yu Xiaoling , Ni Caifang 
Published: January 2023

Objective:
To compare the diagnostic efficacy of serological indices and ultrasound (US) variables in hepatitis B virus (HBV) liver fibrosis staging using random forest algorithm (RFA) and traditional methods.

Methods:
The demographic and serological indices and US variables of patients with HBV liver fibrosis were retrospectively collected and divided into serology group, US group, and serology + US group according to the research content. RFA was used for training and validation. The diagnostic efficacy was compared to logistic regression analysis (LRA) and APRI and FIB-4 indices.

Results:
For the serology group, the diagnostic performance of RFA was significantly higher than that of APRI and FIB-4 indices. The diagnostic accuracy of RFA in the four classifications (S0S1/S2/S3/S4) of the hepatic fibrosis stage was 79.17%. The diagnostic accuracy for significant fibrosis (≥S2), advanced fibrosis (≥S3), and cirrhosis (S4) was 87.99%, 90.69%, and 92.40%, respectively. The area under the curve (AUC) values were 0.945, 0.959, and 0.951, respectively. For the US group, there was no significant difference in diagnostic performance between RFA and LRA. The diagnostic performance of RFA in the serology + US group was significantly better than that of LRA. The diagnostic accuracy of the four classifications (S0S1/S2/S3/S4) of the hepatic fibrosis stage was 77.21%. The diagnostic accuracy for significant fibrosis (≥S2), advanced fibrosis (≥S3), and cirrhosis (S4) was 87.50%, 90.93%, and 93.38%, respectively. The AUC values were 0.948, 0.959, and 0.962, respectively.

Conclusion:
RFA can significantly improve the diagnostic performance of HBV liver fibrosis staging. RFA based on serological indices has a good ability to predict liver fibrosis staging. RFA can help clinicians accurately judge liver fibrosis staging and reduce unnecessary biopsies.
Perceived fear and anxiety as an after effect among coronavirus disease-2019 patients and their treating doctors
Authors: Srivastava Rani , Kumar Ashok , Saran Brijesh , Bhagat Tripta , Bansal Shivani , Tyagi Anita , Srivastava Yashaswini 
Published: January 2023

Introduction:
Coronavirus disease-2019 (COVID-19) represented a human tragedy among the general population and has been an unprecedented challenge for patients, treating doctors, and the entire world. This fact has created continuous fear, anxiety, and many more psychological discomforts such as impairment in healthy happy life, drug abuse, increased religiosity, and hopelessness, and it is also being noticed that women and women-treating doctors are found to be more prone to catch psychological disturbances.

Objective:
Considering all the above challenges, this study was intended to test the general health, level of fear, anxiety, and general well-being of COVID afflicted individuals and their treating doctors.

Methodology:
Here, the general well-being, level of anxiety, stress, and fear of COVID-19 patients and their treating doctors are examined. This study has been counducted online for COVID-19 patients (with Telephonic calls) and direct interview of treating doctors. The patient's details were taken from hospital records to contact them online. On the other side, the faculty of their treating doctors who have been physically involved in this project were examined for psychological testing. This study has been conducted in the Department of Clinical Psychology in collaboration with Medicine, Santosh Medical College, Hospitals, Ghaziabad, UP.

Results and Discussion:
Out of 1325 total cases, only 34% of cases took interest to provide us feedback after recovery. Approximately the similar proportion of cases, i.e., 35% did not respond but rather gave silly rationales as if they did not want to be recognized. One of the smartest groups of such population was who were proved to be highly fake as they furnished all fake identities even during their admission. It was very shocking. COVID patients did not reveal any serious psychopathology. Now if we compare the psychological profile of treating doctors (faculty and PG), their overall health has shown remarkable concerns means their mental health is affected.

Conclusion:
Therefore, this study concludes that the knowledge and perception about this pandemic and factors associated with anxiety/depression among frontline physicians are needed to be taken care of because it is marked among the doctors of Santosh Hospital.
ANALISIS FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEIKUTSERTAAN KELAS IBU HAMIL PADA MASA PANDEMI COVID-19
Authors: Mamlukah Mamlukah , Harmilah Ilah Siti , Febriani Esty 
Published: January 2023

Angka Kematian Ibu (AKI) merupakan salah satu indikator untuk mengukur derajat kesehatan. Salah satu penyebab tidak langsung diantaranya adalah ibu hamil tersebut tidak mengikuti kegiatan kelas ibu hamil. Kelas ibu hamil di Indonesia sudah terbentuk 89,9% kelas ibu hamil dari 9.993 Puskesmas dan rata-rata tingkat partisipasi kelas ibu hamil masih di bawah 75%. Tingkat partisipasi kelas ibu hamil di Puskesmas Sumedang Selatan masih rendah baru mencapai 50%. Tujuan penelitian untuk mengetahui faktor predisposisi dan faktor penguat yang berhubungan dengan keikutsertaan kelas ibu hamil di wilayah kerja Puskesmas Sumedang Selatan pada masa pandemi Covid-19. Rancangan penelitian cross sectional dengan jumlah sampel 90 responden. Analisis dilakukan dengan unvaried, bivariate dan multivariate. Pengumpulan data dengan wawancara menggunakan kuesioner. Analisis bivariate dari 4 variabel yang diteliti didapatkan hasil hubungan pekerjaan dengan keikutsertaan kelas ibu hamil nilai p:0,011, pengetahuan dengan nilai p: 0,019, sikap dengan nilai p : 0,007 dan dukungan suami dengan nilai p : 0,026. Terdapat hubungan antara variabel pekerjaan, pengetahuan, sikap dan dukungan suami dengan keikutsertaan kelas ibu hamil di wilayah kerja Puskesmas Sumedang Selatan pada masa pandemi covid-19. Perlu adanya evaluasi secara berkala dalam pelaksanaan kelas ibu hamil di puskesmas, untuk perbaikan dan tindak lanjut ke depan.
PERENCANAAN STRATEGIS SISTEM INFORMASI PADA SD NEGERI SAMIRONO MENGGUNAKAN METODE WARD AND PEPPARD
Authors: Karismanto Yogi Danar , Tanaem Penidas Fiodinggo 
Published: January 2023

SD Negeri Samirono adalah lembaga pendidikan formal di Republik Indonesia yang bekerja di bawah pengawasan langsung Kementerian Pendidikan dan Kebudayaan. Di era ini organisasi dan perusahaan harus beradaptasi dengan perkembangan teknologi baru untuk tumbuh dan tetap kompetitif. SD Negeri Samirono telah menggunakan teknologi dalam operasionalnya, namun belum sepenuhnya terintegrasi. Perencanaan strategis sangat penting untuk sistem informasi agar lebih berhasil dalam penerapannya dan berkontribusi pada pencapaian tujuan dan visi/misi mereka. Pendekatan Ward dan Peppard telah digunakan selama beberapa dekade sebagai strategi perencanaan strategis untuk sistem informasi. Metode ini mencakup analisis atau kajian lingkungan teknologi informasi internal dan eksternal, serta lingkungan bisnis internal dan eksternal, yaitu dengan menggunakan analisis SWOT dan analisis Value Chain. Output yang dihasilkan dari pendekatan perencanaan strategis ini menghasilkan pembuatan portofolio aplikasi, yang selanjutnya dipetakan menggunakan McFarlan Strategic Grid. Temuan akhir studi ini mencakup rekomendasi untuk pembuatan dan perbaikan aplikasi atau sistem untuk dikembangkan dan diimplementasikan. Antara lain sistem informasi PPDB, sistem informasi akademik, sistem informasi sarana prasarana, website company profile sekolah, e-absensi dan e-learning. Tujuan dari penelitian ini adalah supaya output yang direkomendasikan dapat dijadikan acuan untuk pengembangan dan implementasi sistem informasi pada SD Negeri Samirono. Sehingga melalui acuan tersebut dapat membantu SD Negeri Samirono lebih unggul, kompetitif dan lebih berprestasi.
ANALISIS KEMAMPUAN GURU PENGGERAK PADA JENJANG SEKOLAH DASAR DI WILAYAH PERBATASAN DALAM PERSPEKTIF LITERASI TEKNOLOGI DIGITAL
Authors: Silvester Silvester , Purnasari Pebria Dheni , Aurelly Betrishandi Titia , Gunawan Rendi 
Published: January 2023

Penelitian ini bertujuan untuk menganalisis kemampuan guru penggerak pada jenjang sekolah dasar di wilayah perbatasan dalam perspektif literasi teknologi digital. Penelitian ini merupakan jenis penelitian kualitatif dengan pendekatan kualitatif deskriptif. Sumber data dalam penelitian diperoleh melalui observasi, studi pustaka, dan wawancara yang dilakukan bersama responden. Adapun subjek dalam penelitian ini adalah 5 orang guru penggerak yang berada di wilayah Kabupaten Bengkayang. Teknik pemilihan responden dilakukan dengan menggunakan purposive sampling. Pemilihan subjek tersebut dilatarbelakangi karena tujuan dari penelitian ini yaitu untuk menganalisis kemampuan guru penggerak di Wilayah Perbatasan dalam Perspektif Literasi Teknologi Digital. Teknik analisis data dalam penelitian ini menggunakan analisis data yang dikembangkan oleh Miles dan Huberman yaitu dimulai dengan reduksi data, penyajian data dan penarikan kesimpulan dari data yang sudah dikumpulkan. Untuk menguji keabsahan data dalam penelitian ini digunakan teknik triangulasi. Hasil penelitian yang dilakukan di wilayah perbatasan yakni di Kabupaten Bengkayang menunjukkan bahwa sebagian guru penggerak sudah menguasai literasi teknologi digital, hal ini dapat dilihat dari pemahaman para guru penggerak tentang teknologi digital. Para guru berpendapat bahwa teknologi digital merupakan sebuah perkembangan teknologi yang berinovasi sebagai media atau alat yang dapat membantu penggunanya dalam memberikan dan mendapatkan informasi secara praktis. Para guru juga sudah menggunakan berbagai fasilitas teknologi dan memanfaatkan teknologi digital ini sebagai media pembelajaran dalam proses pembelajaran sebagai pemberian materi dan evaluasi pembelajaran serta dapat dimanfaatkan sebagai sumber belajar bagi para peserta didik dan para guru. Namun belum sepenuhnya para guru memanfaatkan teknologi digital sebagai media pembelajaran maupun evaluasi pembelajaran. Hal ini karena kondisi wilayah perbatasan masih tertinggal dan belum merata dalam aspek infrastruktur pendukung pendidikan.
KAPASITAS NILAI KUAT TEKAN BETON DENGAN HAMMER TEST DAN ULTRASONIC PULSE VELOCITY (UPV) JEMBATAN LOA HAUR
Authors: Tumingan Tumingan , Alwi Salma , H Fendi Ilham 
Published: January 2023

Jembatan Loa Haur merupakan sebuah jembatan tipe rangka baja dengan bentang 60 meter dibangun pada tahun 1992 yang terletak pada Jalan Poros Samarinda – Tenggarong, Desa Bakungan, Kecamatan Loa Janan Kutai Kartanegara Kalimantan Timur. Akibat kondisi lalu lintas dan beban kendaraan yang melintas semakin meningkat di jembatan Loa Haur, untuk keamanan dan kenyamanan pengguna, di perlukan evaluasi struktur jembatannya. Salah satu bagian struktur yang akan dievaluasi pada penelitian ini yakni mutu beton yang terpasang saat ini terhadap standar spesifikasi Bina Marga khususnya sisa kekuatan tekan beton jembatan dengan batas minimal mutu beton 250 Kg/cm2, atau 20 MPa. Pengujian ini mengambil metode non destructive menggunakan alat Hammer test dan alat Ultrasonic Pulse Velocity Test. Pengujian diawali dengan alat rebar locator yang bertujuan untuk mendeteksi diameter dan posisi tulangan dalam elemen beton, serta ketebalan selimut beton dengan memanfaatkan medan elektromagnetik, yang mudah terpengaruh oleh adanya logam/metal berupa tulangan baja di dalam beton, karena alat Ultrasonic Pulse Velocity Test sangat terganggu bila melewati baja tulangan. Dilanjutkan dengan pengujian menggunakan alat Hammer test dengan mengambil sebanyak 120 titik pada abutmentt dan 63 titik pada Pelat lantai. Untuk alat UPV dengan metode Tidak Langsung mengambil sampel sebanyak 49 titik pada abutmentt dan 20 titik pada plat lantai jembatan. Hasil analisis pengujian diperoleh nilai kekuatan tekan beton menggunakan alat Hammer test pada abutment dan pelat lantai jembatan masih memenuhi standar spesifikasi jembatan yaitu sebesar 479 kg/cm2 dan 454 kg/cm2 , sedangkan nilai kekuatan tekan beton hasil uji UPV pada abutment dan pelat lantai juga masih memenuhi standar spesifikasi jembatan yaitu sebesar 265 kg/cm2 dan 243 kg/cm2.
IMAJINASI PEREMPUAN DALAM MEDIA POSTER SINGAPORE GIRL DALAM IKLAN SINGAPORE AIRLINES
Authors: Budiardjo Hardman , Sulistiowati Sulistiowati , Sutikno Sutikno , Setyawan Henry Bambang , Tjandrarini A. B. 
Published: January 2023

Penelitian ini dilakukan untuk mengidentifikasi imajinasi tentang perempuan dalam media poster Singapore Girl yang dilakukan oleh maskapai Singapore Airlines. Penelitian ini dilakukan untuk mengidentifikasi poster tersebut yang berkaitan dengan imajinasi perempuan dalam iklan poster Singapore Girls yang dihubungkan dengan nilai individu dan nilai perusahaan. Penelitian yang berhubungan dengan media above the line dan yang dikaitkan dengan nilai diri belum pernah dilakukan. Penelitian yang ada berhubungan lebih menekankan terhadap nilai individu dan berhubungan dengan nilai perusahaan dan tidak menggunakan media poster. Penelitian yang dilakukan menggunakan metodologi visual dengan site of image it self pada tataran modality social. Site of image it self merupakan pemaknaan dari sudut pandang peneliti. Peneliti dalam hal ini bersifat tunggal tidak berfungsi sebagai audien dalam mengintepretasikan visual image yang dihubungkan dengan konteks. Dengan mendasarkan pada realitas sosial, peneliti harus aktif mengamati gambar, tanda dan mengaitkannya dengan konteks untuk mengidentifikasikan tujuan pesan disampaikan. Penelitian ini menggunakan teori Semiotika Roland Barthes sebagai pisau bedah atau unit analisis. Tahapan dalam penelitian ini dilakukan dengan mengamati poster iklan secara mendalam, yang dilanjutkan dengan mengamati potongan-potongan gambar yang akan dianalisis berdasarkan referensi-referensi yang ada. Hasil penelitian menunjukkan bahwa poster iklan Singapore Girls pada maskapai Singapore Airlines memiliki konotasi great individual value dan great corporate Value pada tataran pertama. Pada tataran kedua great individual value adalah mitos. Inilah gambaran paradoks tentang great individual value dan great corporate value hasil konstruksi media yang tidak terlepas dari politik ekonomi yang berhubungan dengan kapitalis.