bluuebunny/crossref_metadata_2025_split huggingface dataset:
The light at the end of the tunnel: marketing to seniors
Authors: Hirsch Peter Buell 
Published: March 2023

Purpose
This paper aims to address the continuing absence of older individuals portrayed across the advertising spectrum.

Design/methodology/approach
A selective citation of research about seniors as a powerful wealth segment and growing demographic contrasted with their almost complete absence from any advertising/marketing other than for products for the “aged.”

Findings
The research clearly demonstrates that older people are active buyers of consumer products, especially digital products and that stereotypes about the behaviors and opinions of classic generational cohorts are invalid.

Research limitations/implications
This viewpoint is based on selective citations from the relevant literature and makes no claim to being a comprehensive review.

Practical implications
If the recommendations suggested in the viewpoint are adopted, people should see more older people depicted sensitively in a wider range of product categories from cell phones to detergent.

Social implications
If the viewpoints expressed in the article being widely known and understood, people should see a reduction in the careless stereotyping of Boomers, Millennials and other cohorts, leading to greater empathy and understanding.

Originality/value
The viewpoint brings together many disparate threads around marketing to seniors and generational cohort stereotyping in a way that has not been done before, to the best of the author’s knowledge.
The interplay between corporate social responsibility and knowledge management strategies for innovation capability development in dynamic environments
Authors: González-Ramos M. Isabel , Donate Mario J. , Guadamillas Fátima 
Published: March 2023

Purpose
This paper aims to analyze unexplored connections between economic, environmental and social dimensions of corporate social responsibility (CSR) and knowledge management (KM) strategies (exploration, exploitation), also considering environmental dynamism as an influencing variable on these connections. The predicted CSR-KM interplay suggests, from stakeholder and knowledge-based views of the firm, the existence of ideal configurations between CSR and KM strategies that generate differentiated impacts on companies’ innovation capabilities, especially in dynamic environments.

Design/methodology/approach
Structural equation modeling by means of the partial least squares technique was used to test the study’s hypotheses after collecting survey data from Spanish companies of the renewable energy sector.

Findings
The study findings show that in highly dynamic environments, companies will tend to commit prominently in CSR, although their orientation (economic, environmental, social) and effects on innovation capabilities will depend mainly on the selected KM strategies. Social and environmental CSR are found to be highly related to KM exploration, whereas economic CSR is highly related to KM exploitation. Nevertheless, while a significant indirect effect of economic CSR by means of the KM exploitation strategy on innovation capabilities is found, the proposed indirect effect of both environmental and social CSR through the KM exploration strategy on innovation capabilities is not significant.

Practical implications
The results suggest that company managers should be aware of the advantages of following specific paths of investment in KM and CSR initiatives in highly dynamic environments, as there is a potential payoff in terms of innovation capability improvement. The results also suggest that “good” relationships with stakeholders, built from specific CSR investments, make firms able to get valuable knowledge that it is useful to develop KM strategies for innovation capability development.

Originality/value
Previous studies do not consider the interplay between KM strategies and CSR as a catalyzer for developing a firm’s innovation capabilities. This paper contributes to the KM and innovation literatures by introducing CSR into the conversation about how to improve innovation capabilities in dynamic and sustainable industries by using configurations of KM strategies and specific CSR investments in economic, social and environmental areas.
Beyond Relevance and towards Utilization: Academic Perspective Taking and the Experience of Surprise as a Proposed Indicator of Impact on Practice
Authors: Paterson Ted A. , Harms Peter D. , Erin Bass Andrea 
Published: March 2023

AbstractWe propose that a pluralistic conceptualization of scholarly impact includes surprise in addition to the more established relevance construct. We identify competing perspectives on the nature of the relevance–surprise relationship and test these perspectives empirically. Results suggest that when managers rate research findings, there is a very strong negative relationship between relevance and surprise; however, when rated by academics attempting to predict managerial responses, the relationship is orthogonal. We also find that academics are generally adept at predicting managers’ ratings of relevance and surprise when presented with academic research findings. Our findings are encouraging in that they suggest that academics are adept at perspective taking; however, they simultaneously highlight a challenge for academics because their most surprising research findings may be dismissed as irrelevant by managers.
The origins of hospital food: Where does it come from and what do staff, patients and suppliers think about local food?
Authors: Carino Stefanie , Misale Georgia , Egan Meredith , Collins Jorja 
Published: March 2023

AbstractAimsTo identify the origin of fresh and minimally processed foods served to hospital patients, and explore the challenges and enablers to local food procurement in hospitals.MethodsA mixed methods study was conducted in a healthcare network in Victoria, Australia. Packaging labels and product information were used to audit fresh and minimally processed foods purchased in 1 week. Processed food items and meals made offsite were not audited. Interviews were conducted with patients, staff and suppliers to explore their perspectives towards local food in hospitals. Framework analysis was used to identify themes.ResultsOf 105 food products audited, 32% were imported, 25% were ‘local’ from Victoria and the remaining 43% were from within Australia (excluding Victoria). Qualitative interviews revealed several challenges including: increased cost of local food items, inconsistent supply and variable quality of local produce, difficulty accessing origin information, and lack of autonomy for hospitals to make food procurement choices. Enablers included: conducting a food origin audit to increase awareness, group purchasing organisation prioritising local food suppliers, and suppliers valuing local produce.ConclusionA food origin audit and interviews with stakeholders provided a rich understanding of current practices and how to increase local food procurement.
Fabrication and design of poly(l‐lactic acid) membrane for passive MAP packaging of Brassica chinensis L
Authors: Yun Xueyan , Lu Hao , Zhou Ziyi , Yuan Shuai , Wang Yangyang , Dong Tungalag 
Published: March 2023

AbstractPLDxL copolymers were synthesized from physically stable rigid poly(l‐lactic acid) (PLLA) and a few different molecular weights of polydimethylsiloxane (PDMS) to increase the O2 and CO2 permeabilities of PLLA films and make them acceptable for packaging highly respirable products. The effect of PDMS on the morphology, mechanical properties, and gas permeability of PLDxL was investigated. Copolymers showed approximately 10 times the fracture strain and 1.7 times the CO2 and O2 permeabilities of neat PLLA. Additionally, PLDxL maintained an increased CO2/O2 perm‐selectivity consistent between 5 and 40°C. Passive modified atmosphere packaging of Brassica chinensis L was developed to assess the membrane's impact on headspace gas inside the package. The results showed that poly(amide)/poly(ethylene) packaging with 48 cm2 PLD1.8L membrane as a breathing window can provide 50 g B. chinensis L. with a healthy atmosphere of 3%–8% O2 and 5%–8% CO2 between 6 and 22 days. Vegetables packaged in PLD1.8L had the lower respiration rate, lower nitrite contents, and less proliferation of microorganisms. Moreover, a suitable atmosphere kept vegetables with higher ascorbic acid and a good appearance after more than 2 weeks of storage at 5°C.Practical ApplicationThe permeability of the PLLA‐based membrane can be adjusted for the breathable window membrane of sealed fresh products. In the future, several types of film could be developed to match the respiratory and metabolic characteristics of different kinds of products. Such PLLA‐based specialized membranes can refine the fresh‐keeping function and be more attractive to the customer.
Factors related to COVID‐19 mortality among three Swedish intensive care units—A retrospective study
Authors: Taxbro Knut , Hammarskjöld Fredrik , Nilsson Mats , Persson Magnus , Chew Michelle S. , Sunnergren Ola 
Published: March 2023

AbstractBackgroundMortality due to acute hypoxemic respiratory failure (AHRF) in patients with coronavirus disease‐19 (COVID‐19) differs across units, regions, and countries. These variations may be attributed to several factors, including comorbidities, acute physiological derangement, disease severity, treatment, ethnicity, healthcare system strain, and socioeconomic status. This study aimed to explore the features of patient characteristics, clinical management, and staffing that may be related to mortality among three intensive care units (ICUs) within the same hospital system in South Sweden.MethodsWe retrospectively analyzed ICU patients with COVID‐19 and AHRF in Region Jönköping County, Sweden. The primary outcome was the 90‐day mortality rate. We used univariate and multivariable logistic regression analyses to investigate the relationship of predictors with outcomes.ResultsBetween March 15, 2020, and May 31, 2021, 331 patients with AHRF and COVID‐19 were admitted to the three ICUs. There were differences in disease severity, treatments, process‐related factors, and socioeconomic factors between the units. These factors were related to 90‐day mortality. After multivariable adjustment, age, severity of acute respiratory distress syndrome, and the number of nurses per ICU‐bed independently predicted 90‐day mortality.ConclusionAge, disease severity, and nurse staffing, but not treatment or socioeconomic status, were independently associated with 90‐day mortality among critically ill patients with AHRF due to COVID‐19. We also identified variations in care related processes, which may be a modifiable risk factor and warrants future investigation.
Do small businesses adjust their capital structure? Evidence from the global financial crisis in Japan
Authors: Tsuruta Daisuke 
Published: March 2023

AbstractWe investigate the extent to which small businesses adjust their capital structures to target levels when their leverage increases substantially during a financial crisis. We examine Japan's Emergency Credit Guarantee (ECG) program during the 2008 global financial crisis. The increased leverage from the use of the ECG program during the crisis increased the probability of default. Additionally, small businesses adjusted their leverage ratios to the target range before the crisis. However, such adjustments were weak during and after the crisis, particularly for target firms in the ECG program.
Country environmental, social and governance performance and economic growth: The international evidence
Authors: Wang Jiazhen , Yu Jing , Zhong Rui 
Published: March 2023

AbstractThis study documents a significant and positive impact of country‐level environmental, social and governance (ESG) improvement on economic growth using an international sample of 109 countries through improving energy efficiency, promoting human‐capital accumulation and attracting foreign investments. The economic benefits of country‐level ESG improvement are robust after alleviating possible endogeneity concerns. Further analysis shows that the positive influence of country ESG performance on economic growth is most pronounced in high‐income countries and for high‐greenhouse gas emitters but weaker in countries whose national income relies on natural resources. Our findings provide policy implications for promoting sustainable economic growth.
Topographic anatomy and vascularization of the glandula thyroidea in rats
Authors: Nur Ismail Hakki , Pérez William , Rutland Catrin Sian 
Published: March 2023

AbstractTopographical anatomy and detailed measurements of the glandula thyroidea (thyroid gland) and the glandula parathyroidea (parathyroid gland) were determined in rats, with significant differences identified between the sexes. In the rats (N = 10 male, 10 female), the glandula thyroidea were positioned at the level of the C1 and C2 vertebrae. One glandula parathyroidea was present in each glandula thyroidea lobe, localized in the cranial part of the lateral lobes in 60% of the animals. There was no glandula thyroidea left lobe in one female and no isthmus in two females. Both the A. thyroidea cranialis and the A. pharyngea ascendens originated from the A. carotis externa, which acted as a common trunk. On the left, the A. thyroidea caudalis originated from the truncus brachiocephalicus in all rats and on the right side was found to originate from both the truncus costocervicalis and the A. subclavia dextra in three females, and only from the truncus costocervicalis in seven females. The V. thyroidea cranialis opened into the V. jugularis interna in the neck region and at the level of the apertura thoracis cranialis, and the V. jugularis interna united with the V. thyroidea caudalis. In addition, on the right, the V. thyroidea cranialis joined the V. jugularis interna, at the level of the A. subclavia. The veins on both sides opened into the V. cava cranialis. Significant differences were observed between the sexes and detailed anatomical analysis of the glandula thyroidea and the glandula parathyroidea, and related vasculature and innervation, have been described in this paper.
Relationship between residential aged care facility characteristics and breaches of the Australian aged care regulatory standards: non‐compliance notices and sanctions
Authors: Alan Janine , Randall Sean , Ferrante Anna , Porock Davina 
Published: March 2023

AbstractObjectivesTo examine the relationship between structural characteristics of Australian residential aged care facilities (RACFs) and breaches of the aged care quality standards.MethodsFacility‐level analysis of audits, sanctions and non‐compliance notices of all accredited Australian RACFs between 2015/16 and 2018/19. Structural factors of interest included RACF size, remoteness, ownership type and jurisdiction. Two government data sources were joined. Each outcome was analysed to calculate time trends, unadjusted rates and relative risks.ResultsNon‐compliance notices were imposed on 369 RACFs (13%) and 83 sanctions on 75 RACFs (3%). Compared with New South Wales (NSW), non‐compliance notices were less likely in Victoria, Queensland and the Northern Territory (NT), more likely in South Australia (SA), and comparable in Western Australia (WA), Tasmania and the Australian Capital Territory (ACT). RACFs with more than 100 beds and RACFs located in remote and outer regional areas (vs. major cities) also increased the likelihood of non‐compliance notices. Compared with NSW, sanctions were less likely in Victoria, Queensland, NT and WA and comparable in SA, Tasmania and ACT. Additionally, the likelihood of sanctions was higher for RACFs with more than 40 beds. For both non‐compliance notices and sanctions, no significant relationship was found with RACF ownership type.ConclusionsWe partially confirmed other Australian findings about the relationship between RACF structural characteristics and regulatory sanctions and reported new findings about non‐compliance notices. Routine and standardised public reporting of RACF performance is needed to build trust that Australia's latest aged care reforms have led to sustained quality improvements.
Incidence and risk factors for neoplasia in inflammatory bowel disease
Authors: Garcia Joana Lemos , Rosa Isadora , da Silva João Pereira , Moleiro Joana , Claro Isabel 
Published: March 2023

AbstractIntroductionInflammatory Bowel Disease (IBD) patients may have an increased risk of neoplasia. The aim was to evaluate the incidence of malignant neoplasia in IBD patients, associated risk factors and therapy adjustments.MethodsUnicentric retrospective cohort study. All patients followed for IBD in a tertiary portuguese hospital and oncological centre during 2015–2020 were included.Results318 patients were included female 55.0%, age at diagnosis = 37.24(±15,28), Crohn's disease 52.5%, Primary Sclerosing Cholangitis n = 7, family history of cancer n = 12, previous diagnosis of neoplasia n = 23(7.2%). 42 cancers were diagnosed in 35 patients (11.0%) ‐ median of 12.0(IQR = 7.5‐21.0) years after IBD diagnosis. Most affected organs were the skin (n = 15 in 11 patients; melanoma = 1), colon/rectum (n = 8 in 6 patients), prostate (n = 4), breast (n = 3) and anal canal (n = 2). In those with non‐melanoma skin cancer, 6 were under active treatment with azathioprine and 2 had stopped it for more than two years. In the univariate analysis, the occurrence of neoplasia was positively associated with tobacco exposure (p = 0.022), age at IBD diagnosis (p = 0.021), and negatively with infliximab exposure (p = 0.046). In 9 cases, cancer treatment was different because of the IBD, while IBD treatment was changed in 9 patients. In those affected by cancer, in the univariate analysis, its cure/remission was negatively associated with tobacco exposure (p = 0.004) and positively with salicylates use (p = 0.007).ConclusionIn IBD patients, cancer mostly affected the skin and the lower digestive system. As in the general population, tobacco exposure was a risk factor for the development of neoplasia.
The therapeutic effects of berberine for gastrointestinal cancers
Authors: Davoodvandi Amirhossein , Sadeghi Sahand , Alavi Seyed Mohammad Amin , Alavi Seyedeh Shaghayegh , Jafari Ameneh , Khan Haroon , Aschner Michael , Mirzaei Hamed , Sharifi Mehran , Asemi Zatollah 
Published: March 2023

AbstractCancer is one of the most serious human health issues. Drug therapy is the major common way to treat cancer. There is a growing interest in using natural compounds to overcome drug resistance, adverse reactions, and target specificity of certain types of drugs that may affect several targets with fewer side effects and be beneficial against various types of cancer. In this regard, the use of herbal medicines alone or in combination with the main anticancer drugs is commonly available. Berberine (BBR), a nature‐driven phytochemical component, is a well‐known nutraceutical due to its wide variety of pharmacological activities, including antioxidant, anti‐inflammatory, antibacterial, antifungal, antiparasitic, antidiabetic, antihypertensive, and hypolipidemic. In addition, BBR exerts anticancer activities. In present article, we summarized the information available on the therapeutic effects of BBR and its mechanisms on five types of the most prevalent gastrointestinal cancers, including esophageal, gastric, colorectal, hepatocarcinoma, and pancreatic cancers.
Immune response evolution in peanut epicutaneous immunotherapy forpeanut‐allergicchildren
Authors: Bastin Marie , Carr Warner W. , Davis Carla M. , Fleischer David M. , Lieberman Jay A. , Mustafa S. Shahzad , Helleputte Thibault , Bois Timothée , Campbell Dianne E. , Green Todd D. , Greenhawt Matthew 
Published: March 2023

AbstractBackgroundEpicutaneous immunotherapy with investigational Viaskin™ Peanut 250 μg (DBV712) has demonstrated statistically superior desensitization versus placebo in peanut‐allergic children in clinical trials. It is unclear whether serologic biomarkers predict response.MethodsSerum‐specific IgG4 and IgE (whole peanut and components) from subjects enrolled in the phase 3 Efficacy and Safety of Viaskin Peanut in Children With IgE‐Mediated Peanut Allergy study were examined by exploratory univariate and multivariate analyses to determine trajectories and predictors of treatment response, based upon peanut protein eliciting dose (ED) at Month (M) 12 double‐blind placebo‐controlled food challenge.ResultsAmong Viaskin Peanut‐treated subjects, peanut sIgG4 significantly increased from baseline through M12 and peanut sIgE peaked at M3 and fell below baseline by M12, with sIgG4 and sIgE peanut components mirroring these trajectories. Placebo subjects had no significant changes. By univariate analysis, M12 peanut sIgG4/sIgE was higher in treatment responders (p < 0.001) and had highest area under the curve (AUC) for predicting ED ≥300 mg and ≥1000 mg (AUC 69.5% and 69.9%, respectively). M12 peanut sIgG4/sIgE >20.1 predicted M12 ED ≥300 mg (80% positive predictive value). The best performing component was Ara h 1 sIgE <15.7 kUA/L (AUC 66.5%). A multivariate model combining Ara h 1 and peanut sIgG4/sIgE had an AUC of 68.2% (ED ≥300 mg) and 67.8% (ED ≥1000 mg).ConclusionsPeanut sIgG4 rise most clearly differentiated Viaskin Peanut versus placebo subjects. sIgG4/sIgE ratios >20.1 and the combination of Ara h 1 and peanut sIgG4/sIgE had moderate ability to predict treatment response and could potentially be useful for clinical monitoring. Additional data are needed to confirm these relationships.
Involuntary childlessness: Lessons from interactionist and ecological approaches to disability
Authors: Lee Ji‐Young 
Published: March 2023

AbstractBecause many involuntarily childless people have equal interests in benefitting from assisted reproductive technologies like in vitro fertilization as a mode of treatment, we have normative reasons to ensure inclusive access to such interventions for as many of these people as is reasonable and possible. However, the prevailing eligibility criterion for access to assisted reproductive technologies—'infertility'—is inadequate to serve the goal of inclusive access. This is because the prevailing frameworks of infertility, which include medical and social infertility, fail to precisely capture and unify the relevance of certain involuntarily childless experiences as warranting assisted reproductive technology (ART) treatment. I argue that the least we can do for those who have an interest in accessing ARTs is to conceptualize involuntarily childless experiences in dialogue with interactionist and ecological models of disability, to outline a unified and more inclusive eligibility criterion.