bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent advances in bioelectrochemical detection of E. coli bacteria in saline buffers and spiked real samples using traditional and nanostructured active substrates
Authors: Ionescu Rodica Elena 
Published: March 2023

AbstractA rapid and cost‐effective method to specifically identify and quantify pathogenic Escherichia coli (E. coli) bacteria in aqueous samples and food products is highly recommended to avoid the degradation of human health that can unfortunately lead to fatal cases. To overcome these borderline situations, portable and easy‐to‐use screening devices are needed for the non‐expert public and confirmed by medical personnel/physicians who can quickly guide/prescribe antibiotic treatments. In such a context, nanotechnologies are very promising and useful tools due to the remarkable optical, chemical and physical properties of biocompatible nanomaterials deposited or synthesized on traditional solid electrodes that greatly improve the detection limit and the selectivity of nanostructured‐based biosensors. With this in mind, this review summarizes the latest advances in the bioelectrochemical detection of E. coli and its related products using different biosensor configurations in saline buffers and spiked real samples, namely food products (milk, fruits, vegetables), body fluids (blood, urine, swine feces) and river water.
Stimulating olfactory epithelium mitigates mechanical ventilation‐induced hippocampal inflammation and apoptosis
Authors: Ghazvineh Sepideh , Salimi Morteza , Dehghan Samaneh , Asemi‐Rad Azam , Dehdar Kolsoum , Salimi Alireza , Jamaati Hamidreza , Raoufy Mohammad Reza 
Published: March 2023

AbstractMechanical ventilation (MV), as a life‐saving procedure in critical patients, is a risk factor to develop of neurocognitive dysfunction and triggers of inflammation and apoptosis in the brain. Since diversion of breathing route to the tracheal tube diminishes brain activity entrained by physiological nasal breathing, we hypothesized that simulating nasal breathing using rhythmic air‐puff (AP) into the nasal cavity of mechanically ventilated rats can reduce hippocampal inflammation and apoptosis in association with restoring respiration‐coupled oscillations. We found that stimulating olfactory epithelium through applying rhythmic nasal AP, in association with reviving respiration‐coupled brain rhythm, mitigates MV‐induced hippocampal apoptosis and inflammation involving microglia and astrocytes. The current translational study opens a window for a novel therapeutic approach to reduce neurological complications induced by MV.
Simulating spatial variability of groundwater table in England and Wales
Authors: Rahman M. , Pianosi F. , Woods R. 
Published: March 2023

AbstractGroundwater is a vital natural resource that affects human life and the environment. Groundwater supplies drinking water, supports irrigation for food production, and helps to sustain flow of water in streams and wetlands during dry periods. Therefore, it is important to assess the variability of groundwater resources and consider it in freshwater management. Numerical modelling is widely used for understanding the variability of groundwater table. However, there is still a lack of large‐scale groundwater flow models. For instance, in the United Kingdom, groundwater modelling efforts so far have focused on aquifer to regional scales. A national scale model would aid the quantification of the available groundwater storage and the assessment of the impacts of climate change and anthropogenic activities on this crucial resource. In this study, we evaluate a numerical groundwater flow modelling approach for entire England and Wales. This model operates at 1 km spatial and 1 day temporal resolution. We force the model with precipitation and potential evapotranspiration, parameterise the subsurface using our estimation of transmissivity and specific yield based on available information, and simulate steady‐state groundwater heads over England and Wales. The results demonstrate that the model can reproduce spatial variability of groundwater table in the region. Because of a two‐dimensional numerical representation of groundwater flow, the computational demand of this model is low, facilitating multiple simulations required for calibration, sensitivity analysis, and quantification of the impacts of environmental changes on groundwater resources.
Pathways by which case managers' match support influences youth mentoring outcomes: Testing the systemic model of youth mentoring
Authors: Karcher Michael J. , Sass Daniel A. , Herrera Carla , DuBois David L. , Heubach Janet , Grossman Jean B. 
Published: March 2023

AbstractKeller's systemic model of youth mentoring posits there are multiple pathways through which all stakeholders in the youth mentoring process, including the program staff who support the match (or case managers), influence youth outcomes. This study examines case managers' direct and indirect contributions to match outcomes and tests how transitive interactions facilitate a theorized sequence of mentoring interactions to effect greater closeness and length, specifically in nontargeted mentoring programs. A structural equations model of case manager contributions to match outcomes was tested using data from 758 mentor‐mentee matches, supported by 73 case managers across seven mentoring agencies. Results reveal direct effects of mentor‐reported match support quality on match length and indirect influences on match length through increasing youth‐centeredness, goal‐focused orientation, and closeness. The findings confirm the presence of multiple pathways of influence, including indirect effects on outcomes via transitive interactions in match support that scaffold youth‐centeredness and goal‐focused interactions in the match. Findings also suggest supervisors' evaluations of case managers may provide little information about how match support influences the nature of mentor–mentee interactions.
Comparison of oxidative stress response of in vitro retinal cells exposed to blue light from emissive versus reflective displays
Authors: Wang Xiaodong , Hertel Dirk , Garone Lynne C. , Rogers Rick A. 
Published: March 2023

AbstractDuring COVID‐19, there was increased use of handheld displays in educational settings. There is growing concern that eye health may be affected by prolonged exposure to the light‐emitting diodes used as frontlights or backlights in handheld displays. The potential impact of light exposure from tablet‐sized devices with different display technologies and various spectral outputs was assessed in an in vitro model using human retinal epithelial (ARPE‐19) cells. Cellular response was quantified by measuring reactive oxidative species (ROS) and by analyzing mitochondrial morphology. Control experiments established a baseline ROS response to hazardous blue light exposure and also that red light resulted in no detectable ROS response. Under identical conditions, ROS response increased with time for all devices. However, different device spectra caused ROS to accumulate at different rates. When operating the devices in the same mode (day or night), cells accumulated ROS two to three times more slowly on exposure to frontlit electronic paper displays compared to backlit liquid crystal displays. With increasing ROS accumulation, mitochondrial morphology shifted from elongate interconnected features typically observed under normal conditions to rounded disconnected features associated with oxidative stress response.
A microwave‐assisted extraction method combined with magnetic ionic liquid‐based dispersive liquid–liquid microextraction for the extraction of chloramine–T from fish samples prior to its determination by high‐performance liquid chromatography
Authors: Alizadeh Panahi Arshia , Javadi Afshin , Afshar Mogaddam Mohammad Reza 
Published: March 2023

In the present work, a combination of microwave‐assisted extraction with magnetic ionic liquid–based dispersive liquid–liquid microextraction was developed for the extraction of chloramine–T from fish samples. In this method, the sample was mixed with a hydrochloric acid solution and exposed to microwave irradiations. By doing so, chloramine–T was converted to p–toluenesulfonamide and extracted from the sample into an aqueous phase. Then, a mixture of acetonitrile (as a dispersive solvent) and magnetic ionic liquid (as an extraction solvent) was rapidly injected into the obtained solution. In the following, the magnetic solvent droplets including the extracted analytes were isolated from the aqueous solution in the presence of an external magnetic field and after diluting with acetonitrile injected into high‐performance liquid chromatography equipped with a diode array detector. Under the optimum extraction conditions, high extraction recovery (78%), low limits of detection (7.2 ng/g) and quantification (23.9 ng/g), good repeatability (relative standard deviations ≤5.8 and 6.8% for intra– and inter‐day precisions, respectively), and wide linear range (23.9–1000 ng/g) were obtained. Finally, various fish samples marketed in Tabriz city (East Azarbaijan, Iran) were analyzed with the suggested method.
The application of targeted muscle reinnervation in lower extremity amputations: A systematic review
Authors: Berger Lauren E. , Shin Stephanie , Haffner Zoë K. , Huffman Samuel S. , Spoer Daisy L. , Sayyed Adaah A. , Franzoni Garrett , Bekeny Jenna C. , Attinger Christopher E. , Kleiber Grant M. 
Published: March 2023

AbstractBackgroundTargeted muscle reinnervation (TMR) is a promising surgical modality for reducing post‐amputation pain. We sought to provide a succinct overview of TMR specific to the lower extremity (LE) amputation population.MethodsA systematic review was performed per PRISMA guidelines. Ovid MEDLINE, PubMed, and Web of Science were queried for records using various combinations of Medical Subject Heading (MeSH) terms such as “LE “amputation,” “below‐knee amputation” (BKA), “above‐knee amputation” (AKA), and “TMR.” Primary outcomes included (1) operative techniques, (2) changes in neuroma, phantom limb pain (PLP), or residual limb pain (RLP), and (3) postoperative complications. Studies were only included if outcomes data were discretely provided for LE patients.ResultsEleven articles examining 318 patients were identified. Average patient age was 47.5 ± 9.3 years, and most patients were male (n = 246, 77.4%). Eight manuscripts (72.7%) described TMR at the index amputation. The average number of nerve transfers performed per TMR case was 2.1 ± 0.8, and the most commonly employed nerve was the tibial (178/498; 35.7%). Nine (81.8%) articles incorporated patient‐reported outcomes after TMR, with common methods including the Numerical Rating Scale (NRS) and questionnaires. Four studies (33.3%) reported functional outcomes such as ambulation ability and prosthesis tolerance. Complications were described in seven manuscripts (58.3%), with postoperative neuroma development being the most common (21/371; 7.2%).ConclusionsThe application of TMR to LE amputations is effective in reducing PLP and RLP with limited complications. Continued investigations are warranted to better understand patient outcomes specific to anatomic location using validated patient‐reported outcome measures (PROM).
Temporal contexts for motion tracking in ultrasound sequences with information bottleneck
Authors: Sun Mengxue , Huang Wenhui , Zhang Huili , Shi Yunfeng , Wang Jiale , Gong Qingtao , Wang Xiaoyan 
Published: March 2023

AbstractBackgroundRecently, deep convolutional neural networks (CNNs) have been widely adopted for ultrasound sequence tracking and shown to perform satisfactorily. However, existing trackers ignore the rich temporal contexts that exists between consecutive frames, making it difficult for these trackers to perceive information about the motion of the target.PurposeIn this paper, we propose a sophisticated method to fully utilize temporal contexts for ultrasound sequences tracking with information bottleneck. This method determines the temporal contexts between consecutive frames to perform both feature extraction and similarity graph refinement, and information bottleneck is integrated into the feature refinement process.MethodsThe proposed tracker combined three models. First, online temporal adaptive convolutional neural network (TAdaCNN) is proposed to focus on feature extraction and enhance spatial features using temporal information. Second, information bottleneck (IB) is incorporated to achieve more accurate target tracking by maximally limiting the amount of information in the network and discarding irrelevant information. Finally, we propose temporal adaptive transformer (TA‐Trans) that efficiently encodes temporal knowledge by decoding it for similarity graph refinement. The tracker was trained on 2015 MICCAI Challenge on Liver Ultrasound Tracking (CLUST) dataset to evaluate the performance of the proposed method by calculating the tracking error (TE) between the predicted landmarks and the ground truth landmarks for each frame. The experimental results are compared with 13 state‐of‐the‐art methods, and ablation studies are conducted.ResultsOn CLUST 2015 dataset, our proposed model achieves a mean TE of 0.81 ± 0.74 mm and a maximum TE of 1.93 mm for 85 point‐landmarks across 39 ultrasound sequences in the 2D sequences. Tracking speed ranged from 41 to 63 frames per second (fps).ConclusionsThis study demonstrates a new integrated workflow for ultrasound sequences motion tracking. The results show that the model has excellent accuracy and robustness. Reliable and accurate motion estimation is provided for applications requiring real‐time motion estimation in the context of ultrasound‐guided radiation therapy.
Identifying patterns of kinesiophobia trajectories among COPD patients: A longitudinal study
Authors: Liang Facun , Liu Mengru , Han Hui , Ru Yunxin , Yin Yanru , Cheng Chen , Xue Meng , Gu Lifang 
Published: March 2023

AbstractAimTo determine differences in kinesiophobia levels among COPD patients at different time points 6 months after discharge；To identify potential subgroups of COPD patients who perceived different levels of kinesiophobia over time；and to evaluate differences in identified subgroups based on demographic and disease‐related characteristicsDesignAn observational longitudinal study.MethodsOPD patients hospitalized in respiratory department of a grade A hospital in Huzhou city from October 2021 to May 2022 were selected as the research objects. TSK scale was used to evaluate the level of kinesiophobia at discharge (T1), 1 month after discharge (T2), 4 months after discharge (T3) and 6 months after discharge (T4). The kinesiophobia level scores at different time points were compared using latent class growth modelling. ANOVA and Fisher's exact tests were used to test differences in demographic characteristics，and univariate analysis and multinomial logistic regression analysis were used to explore the influencing factors.ResultsDuring the first 6 months after discharge, kinesiophobia levels decreased significantly in the entire sample of COPD patients. The best‐fitting group‐based trajectory model described three distinctive trajectories: Low kinesiophobia group (31.4% of sample); Medium kinesiophobia group (43.4% of sample)；and High kinesiophobia group (25.2% of sample). Logistic regression results showed that sex, age, course of disease, pulmonary function, education level, BMI, the level of pain, MCFS and mMRC were influencing factors of kinesiophobia trajectory in COPD patients (p < 0.05).
Effects of crystallographic orientation and strain‐hardening on nanoindentation response of cyclotetramethylene tetranitramine (‐HMX) single crystals
Authors: Paliwal Bhasker , Picu Catalin R. 
Published: March 2023

AbstractMechanical behavior of cyclotetramethylene tetranitramine (HMX) is complex and insufficiently understood, but it is imperative as it affects the initiation of the decomposition reaction though hot spots formation. We present a single‐crystal plasticity model for
‐HMX which accounts for pressure dependence of both the elastic constants and the yield surface. We evaluate the relative importance of pressure sensitivity of the elastic constants and plasticity, and of strain hardening, to the quasi‐static mechanical behavior of HMX, in general, and to indentation, in particular. Further, we study the effect of the in‐plane crystallographic orientations of the substrate with respect to the Berkovich indenter tip on the indentation force‐displacement curve. We conclude that pressure sensitivity of plasticity makes the largest contribution to defining the response to indentation, followed by strain‐hardening, sensitivity of which depends on hardening modulus, while the pressure sensitivity of elastic constants play a smaller role. Both the indentation plane normal orientation and the in‐plane indenter tip rotation may influence properties determined from nanoindentation test (e. g. hardness).
Discovery of diversified cassane diterpenoids as potent antibacterial agents from Caesaplinia pulcherrima and their mechanisms
Authors: Chen Xiu‐Mei , Lu Wang , Zhang Zi‐Han , Wang Pan‐Pan , Zhang Xiu‐Juan , Xiao Chao‐Jiang , Zhang Qiang , Gao Jin‐Ming , Li Chun‐Huan 
Published: March 2023

AbstractBACKGROUNDNatural products play a significant role in the development of novel bactericide candidates. Caesalpinia pulcherrima, a traditional medicine, had anti‐inflammatory, antimicrobial, and antifeedant activities, therefore the previous bioassay results of C. pulcherrima implied that its main active ingredients may have potential to be used as botanical bactericides.RESULTSBio‐guided isolation of C. pulcherrima was conducted to obtain 11 novel cassane diterpenoids (capulchemins A–K) and 10 known sesquiterpenes. Their structures were established by extensive spectroscopic methods and single‐crystal X‐ray diffraction analyses. Capulchemins A–F possess a rare aromatic C ring, while capulchemin K with a 15,16‐degradative carbon skeleton represents a rare group of cassane diterpenes. Capulchemin A exhibited remarkable antibacterial activity against four phytopathogenic bacteria, particularly against Pseudomonas syringae pv. actinidae and Bacillus cereus, with minimal inhibitory concentration values of 3.13 μM. Meanwhile, capulchemin A showed significant control effect on kiwifruit canker in vivo. Further investigation of its mechanism of antibacterial activity revealed that compound 1 was closely related to destroy cell membrane to cause cell death. Additionally, some of those cassane diterpenoids showed potential antifeedant against Mythimna separate walker and Plutella xylostella. Consequently, capulchemin A could have the potential to be used as a template for the development for new eco‐friendly NP‐based bactericides.CONCLUSIONThese data contribute to a better understanding of the antibacterial activity of cassane diterpenes. Cassane diterpenes have been discovered to be leading to broad application prospects in the development as novel botanical bactericides. © 2023 Society of Chemical Industry.
Biological Control of Weeds in turfgrass: opportunities and misconceptions
Authors: Neal Joseph C 
Published: March 2023

AbstractTurfgrass systems may offer opportunities for overcoming some constraints on the successful implementation of weed biocontrol. Of the roughly 16.4 million ha of turfgrass in the USA, ≈60–75% are in residential lawns and 3% are golf turf. Annual expenditures for a standard herbicide treatment regimen for residential turf are estimated to be ≈US$326 ha−1, about 2–3‐fold greater than that for USA corn and soybean growers. Expenditures can be >US$3000 ha−1 for control of certain weeds such as Poa annua in high‐value areas including golf fairways or greens, but those applications are made to far smaller areas. Regulatory actions and consumer preferences are creating market opportunities for alternatives to synthetic herbicides in both commercial and consumer markets, but the size of these markets and willingness‐to‐pay are poorly documented. Turfgrass sites are intensively managed, yet despite the ability to modify site conditions through irrigation, mowing and fertility management, microbial biocontrol agents tested thus far have not provided the consistently high levels of weed control expected in the market. Recent advances in microbial bioherbicide products may offer a path to overcome many of the obstacles to success. No single herbicide will control the diversity of turfgrass weeds, nor will any single biocontrol agent or biopesticide. Successful development of weed biocontrol for turfgrass systems will require numerous, effective biocontrol agents for the many weed species found in turfgrass environments, as well as a deeper understanding of different turfgrass market segments, and weed management expectations for each segment. © 2023 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Multilayer self‐organized aggregation control for large‐scale unmanned aerial vehicle swarms
Authors: Pan Zhenhua , Xia Yuanqing , Sun Zhongqi , Yu Tingting 
Published: March 2023

SummaryThe cooperative control of large‐scale unmanned aerial vehicle (UAV) swarms to establish a complex configuration is one of the most challenging goals. The poor scalability of the network topology, inability to self‐organize the desired configuration and the separation of swarm configuration are the main obstructions that hinder the attainment of the goal. This paper studies the self‐organized aggregation control of large‐scale UAVs by designing a scalable distributed network architecture. We present a novel centerless and scalable multilayer graph model to solve the nonextensible problem of the traditional network topology. A large number of UAVs are organized with several interconnected and globally covered layers, and each layer consists of many undifferentiated clusters. Afterwards, a self‐organized aggregation control law using the potential function method is designed for UAVs to realize autonomous configuration and configuration swarming under the consideration of collision and obstacle avoidance.
Intensification of heat and mass transfer in nanomaterial flow over a rotating channel with chemical reaction: A comparative study
Authors: Rehman Aqeel ur , Abbas Zaheer , Ali Amjad , Alzahrani Abdullah Khamis , Asma Mir 
Published: March 2023

AbstractThe current study scrutinizes the impact of heat and mass transfer on the slip flow of a nanofluid in a rotating system, which is designed by two infinite parallel plates. The effects of a magnetic field, thermal radiation, and chemical reaction are also added to the flow system. Copper oxide (CuO) is considered the nanomaterial with drinking water as the base fluid. The governing partial differential equations are transformed into a system of nonlinear ordinary differential equations with the help of similarity transformations. These equations are solved analytically by employing the least square method (LSM) and the Galerkin method (GM). The results computed by these methods are compared with the numerical method such as the Runge–Kutta method of order four (RK4M). The extensive applications of LSM and GM in comparison with RK4M are also presented. Although the attained outcomes are in good agreement, the results obtained with GM are more accurate than that obtained with LSM. Moreover, the contributions of various fluid parameters on the velocity, temperature, and concentration of the fluid are discussed through graphs. Results reveal that the presence of slip in the boundary declines the fluid velocity. The rotational velocity is enhanced with the increment of the rotation parameter. The magnitude of the skin friction coefficient is reduced by increasing the nanoparticle volume fraction while it grows by rising the magnetic parameter. The Nusselt number shows an enhancement with nanoparticle volume fraction, and it yields a slight reduction by increasing the effect of a magnetic field.