bluuebunny/crossref_metadata_2025_split huggingface dataset:
PVC Kan Torbalarının Antimikrobiyal Özelliklerinin ve Biyouyumluluğunun Fiziksel Adsorpsiyon Tekniği ile Artırılması
Authors: ARSLAN Gülşah , KARADEMİR Fikret , AYHAN Fatma 
Published: September 2023

Tek kullanımlık kan torbaları içine alınan kan dondurulmadan en fazla 1 hafta dayanıklıdır. Kan torbalarının içinde antikoagülan olarak sodyum sitrat bulunur. Dondurulduktan sonra çözülerek hastalara verilen kan vücut tarafından etkin şekilde değerlendirilememektedir. Hasta vücutlarının verilen kanı daha etkin bir şekilde kullanabilmesi adına ve kanın daha uzun süre dayanım kazanması ve dondurulup-çözülen kanın şekilli kan hücrelerinde bozulmaları engellemek amacıyla kan torbası iç yüzeyinde bazı yüzey modifikasyon işlemleri yapılmıştır. Dondurulmadan verilecek kanın hastanın iyileşme sürecine etkisinin daha büyük olacağı açıktır. Ticari kan torbalarının biyouyumluluğun arttırılması ve antibakteriyel özellik kazanımı için yüzey modifikasyonu gerçekleştirilmiştir. Bu amaçla, Medikal özellikli Polivinil klorürden (medical grade PVC) üretilmiş tek kullanımlık kan torbalarının kan ile temas halinde olan yüzeylerinin özelliklerinin değiştirilmesinde fiziksel adsorpsiyon yöntemi kullanılmıştır. Konvansiyonel kimyasal adsorbsiyon yöntemleri ile gelen safsızlıkların ve toksisite faktörlerinin azaltılması ve yüzey adsorbsiyon kapasitesinin arttırılması amacıyla bu yöntem seçilmiştir. Sonraki yüzey modifikasyon işlemlerinde fiziksel adsorbsiyon kullanılmıştır. Bu bağlamda kan torbalarının iç yüzeyleri üç farklı yöntem ile modifiye edilmiştir. Fiziksel adsorpsiyon yönteminde biyomalzeme yüzeyleri PEG, AgNP ve PEG+AgNP olmak üzere üç farklı şekilde modifiye edilmişlerdir. Araştırmada Muğla yöresi Liquidambar orientalis Mill. (Sığla ağacı) bitkisinin yaprak özütü kullanılarak gümüş nanoparçacık sentezi gerçekleştirilmiştir. FTIR spektrumları ile yüzeyde oluşan fonksiyonel grup değişimleri belirlenmiş, biyouyumlu malzeme olan PEG’in de biyomalzeme yüzeyindeki varlığı benzer şekilde fonksiyonel gruplar ile doğrulanmıştır. Modifiye edilen yüzeylerin antimikrobiyal aktivitelerini belirlemek amacı ile nazokomyal mikroorganizmaların üremeleri Disk difüzyon yöntemi ile belirlenmiştir. Bakteriler (P. aeruginosa, E. coli, S. aureus, K. pneumoniae, Metisilin dirençli S. aureus) Nutrient besi ortamında, C. albicans ise Saboraud dekstroz besi ortamında aktifleştirildikten sonra Muller Hinton agar bulunan Petri kutularına ekilmişlerdir. Yüzey özellikleri değiştirilen ve belli büyüklükte hazırlanan biyomalzemeler 2 cm aralıklarla besiyerine yerleştirilip inkübasyona bırakılarak süre sonunda inhibisyon zonları ölçülmüştür.
İşlem görmemiş yüzeylerde antimikrobiyal aktivite % 50 iken Fiziksel adsorpsiyon denemerinde bu değer % 89’a ulaşmıştır. Sonuç olarak önerilen Fiziksel adsorpsiyon yöntemi ile nazokomyal mikroorganizma türlerine karşı antimikrobiyal aktivite kazandırmak için kullanılabileceği belirlenmiştir.
Pemanfaatan Lembar Kerja Peserta Didik Berbasis Aplikasi Liveworksheet Sebagai Upaya Meningkatkan Keaktifan dan Prestasi Belajar
Authors: Yulismar Yulismar , Nuzulia Rahma 
Published: September 2023

Permasalahan yang dihadapi oleh guru mata pelajaran di kelas adalah kurangnya minat peserta didik dalam mengerjakan tugas dan banyaknya peserta didik yang tidak hadir dalam pembelajaran. Hal ini tentu akan berdampak pada hasil belajar peserta didik. Guna mengatasi permasalah tersebut, maka peneliti sebagai kepala sekolah melakukan penelitian tindakan dengan memanfaatkan LKPD berbasis liveworksheet guna meningkatkan keaktifan belajar dan prestasi belajar peserta didik. Penelitian tindakan ini terdiri dari 2 siklus. Setiap siklus terdiri dari 4 uraian kegiatan, diantaranya perencanaan, pelaksanaan, pengamatan, dan refleksi. Jumlah guru mata pelajaran yang terlibat adalah 8 orang yang terdiri dari Pendidikan Agama Islam (PAI), PPKn, Bahasa Indonesia, Matematika, IPA, IPS, Seni Budaya serta Bimbingan Konseling (BK). Sedangkan jumlah keseluruhan siswa adalah 287. Analisis data dalam penelitian ini adalah menggunakan metode deskriptif kualitatif. Hasil penelitian tindakan menunjukkan adanya peningkatan persentase keaktifan siswa dalam hal mengerjakan tugas dan kehadiran yang dilihat pada siklus I dan II. Rata-rata kehadiran peserta didik di dalam pembelajaran dari 87% meningkat menjadi 95%, dan rata-rata keaktifan mengerjakan tugas pada siklus dari 79% menjadi 94%. Nilai rata-rata hasil belajar menggunakan LKPD berbasis liveworksheet dari 85 menjadi 92.

The problems in learning are that students frequently did not attend the class and do the exercises or homework. These problems will influence students’ achievement average scores, so the researcher does the school action research for problem-solving by utilizing the Lifeworksheet-based-student worksheet. This action research consists of 2 cycles. Each cycle consists of 4 descriptions of activities, including planning, implementation, observation, and reflection. The number of teachers involved is eight teachers consisting of Islamic Religious Education (PAI), PPKn, Indonesian Language, Mathematics, Science, Social Studies, Cultural Arts, and Counseling Guidance (BK). The total of students are 287. In the Data analysis, the researcher uses qualitative descriptive methods. The results showed an increase in students' percentage of activity in terms of doing assignments and attendance seen in cycles I and II. The average score of learning outcomes using life worksheet-based worksheets increased from 85 to 92. The students' average attendance in online learning from 87% increased to 95%, and the average activity of doing assignments in the cycles from 79% to 94%.
Penanganan Keterlambatan Berbicara Melalui Dongeng Fabel Menggunakan Media Boneka Jari
Authors: Rosida Sisi , Ritonga Ristra Sandra , Losi Rizky Vita 
Published: September 2023

Masalah terlambat berbicaraipada anak prasekolah saat ini menjadi momok utama setiap orang tua. Setiap tahunnya, kasus keterlambatan bicara dipastikan mengalami peningkatan. Anakiyangimengalamii lambat bicara akan menghadapi beberapa hambatan pada iproses ibelajarnya pada sekolah, idiantaranya kesulitan belajar, membaca, imenulis, serta rangkaian problematika kecerdasan. Adapun upaya yang dilakukan buat mengatasi konflik tersebut melalui dongeng fabel memakai boneka jari. Penelitian ini bertujuan mengetahui proses penggunaan dongeng fabel memakai boneka jari dalam menangani keterlambatan bicara di anak. iPenelitian inii memakai metode penelitian lapangan yangi sifatnya naratif kualitatif. Hasil penelitian mendeskripsikan upaya yang dimplementasikan pendidik mengatasi keterlambatan bicara anakiyaitu memakai metode fabel melalui boneka jari. Pemberian ransangan dengan “bermain peran” memakai boneka jari sebagai media yang menumbuhkan rasa percaya diri si anak, melahirkan interaksii secara ilangsung antara anak serta guru yang menganyam komunikasi serta stimulus pada anak. iPerlahan anak yang mengalami iketerlambatan bicara mulai membukai dirinya, mengucapkan kata-kata singkat meskipun ia masih terbata-bata.
Implementasi Pembelajaran Langsung Pendekatan Problem Posing dalam Meningkatkan Hasil Belajar Ikhtisar Siklus Akuntansi Perusahaan Dagang
Authors: Meliwati Meliwati 
Published: September 2023

Ikhtisar siklus akuntansi perusahaan dagang merupakan salah satu kompetensi dasar yang dibahas pada mata pelajaran Ekonomi. Ikhtisar ini termasuk materi esensial yang harus dikuasai siswa karenan elalu keluar dalam soal-soal ujian nasional. Namun, siswa kurang menguasai materi tersebut. Dilihat dari hasil ujian yang rendah. Hal ini dikarenakan siswa pasif kurang responsif selama proses pembelajaran berlangsung. Oleh karena itu, guru memilih model pembelajaran baru untuk meningkatkan keterlibatan siswa melalui pendekatan Problem posing. Tujuan penelitian ini adalah untuk mengetahui peningkatan hasil belajaralam proses pembelajaran, dan mengukur perbedaan hasil belajar setiap siklus dalam proses pembelajaran ikhtisar siklus akuntansi perusahaan dagang dengan pendekatan Problem posing. Hasil penelitian menunjukkan hasil belajar siswa meningkat dengan model pembelajaran Problem posing yang ditunjukkan dari nilai ketuntasan belajar siswa rata-rata di siklus I 66,67 % dan siklus II sebesar 92,86 %.
Pemanfaatan Video Pembelajaran dengan Mengintegrasikan Profil Pelajar Pancasila Melalui Pembelajaran Jarak Jauh pada Program Kampus Mengajar di SD Negeri Jatimulyo 02 Kota Malang
Authors: Muslichah Maria , Mahardhani Ardhana Januar , Azzahra Aisyah Fitri Nur , Safitri Dea Ekwa Cahya , Hardiansyah Hardiansyah , Amala Istiqomah Ahsanu , Nabila Syafira Nur 
Published: September 2023

Penelitian ini bertujuan mengembangkan lingkungan belajar dengan menggunakan video pembelajaran yang interaktif, menyenangkan, dan kompetitif yang menyediakan metode dan konsep sistematis dengan mengintegrasikan profil pelajar Pancasila. Metode yang digunakan dalam penelitian ini adalah studi literatur dengan menelaah berbagai jurnal dan rujukan lain. Hasil dari menelaah berbagai literatur dijadikan acuan peneliti dalam menginovasi video pembelajaran yang berguna mengintegrasikan profil pelajar Pancasila. Kesimpulan dalam penelitian diketahui bahwa dengan video pembelajaran, peserta didik dapat belajar melalui pembelajaran jarak jauh dan memahami tentang profil pelajar Pancasila.
Strategi Ecolip (Ecology Line Up) dalam Pembentukan Sikap Peduli Lingkungan
Authors: Sukmawati Fatma 
Published: September 2023

Masalah kerusakan lingkungan dewasa ini terus mengalami peningkatan yang serius. Salah satu cara untuk mengurangi ancaman kerusakan lingkungan adalah dengan mengubah cara pandang dan sikap siswa untuk lebih peduli terhadap lingkungan. Seiring dengan permasalahan lingkungan yang semakin kompleks, gerakan lingkungan semakin digencarkan dalam konteks pendidikan seperti penggunaan strategi permainan Ecology Line Up (Ecolip) dalam proses pembelajaran. Penelitian ini bertujuan untuk mendeskripsikan pengaruh penerapan strategi ecolip di SMP Kasatrian 1 Surakarta terhadap sikap peduli lingkungan siswa. Peneltian ini merupakan penelitian eksperimen, dengan desain Non equivalent Control Group Design. Sampel penelitian sebanyak 50 peserta didik yang terbagi menjadi dua kelompok, yaitu 25 siswa di kelompok eksperimen dan 25 siswa di kelompok control. Hasil penelitian menggambarkan bahwa penerapan strategi Ecolip berpengaruh terhadap pembentukan sikap peduli lingkungan siswa di sekolah. Kesimpulan dari penelitian ini adalah penerapan strategi permainan Ecolip berpengaruh terhadap sikap peduli lingkungan peserta didik. Penggunaan strategi Ecolip yang dilaksanakan sekolah harus mengacu pada prinsip-prinsip pelestarian lingkungan dan pengendalian pencemaran lingkungan.
Noninvasive assessment of glymphatic dysfunction in idiopathic normal pressure hydrocephalus with diffusion tensor imaging
Authors: Georgiopoulos Charalampos , Tisell Anders , Holmgren Rafael T. , Eleftheriou Andreas , Rydja Johanna , Lundin Fredrik , Tobieson Lovisa 
Published: September 2023

OBJECTIVE
Diffusion tensor imaging (DTI) along the perivascular space (ALPS) (DTI-ALPS)—by calculating the ALPS index, a ratio accentuating water diffusion in the perivascular space—has been proposed as a noninvasive, indirect MRI method for assessing glymphatic function. The main aim of this study was to investigate whether DTI-ALPS would reveal glymphatic dysfunction in idiopathic normal pressure hydrocephalus (iNPH) and whether the ALPS index was associated with disease severity.

METHODS
Thirty iNPH patients (13 men; median age 77 years) and 27 healthy controls (10 men; median age 73 years) underwent MRI and clinical assessment with the Timed Up and Go test (TUG) and Mini-Mental State Examination (MMSE); only the patients were evaluated with the Hellström iNPH scale. MRI data were analyzed with the DTI-ALPS method and Radscale screening tool.

RESULTS
iNPH patients showed significantly lower mean ALPS index scores compared with healthy controls (median [interquartile range] 1.09 [1.00–1.15] vs 1.49 [1.36–1.59], p < 0.001). Female healthy controls showed significantly higher ALPS index scores than males in both hemispheres (e.g., right hemisphere 1.62 [1.47–1.67] vs 1.33 [1.14–1.41], p = 0.001). This sex difference was not seen in iNPH patients. The authors found a moderate exponential correlation between mean ALPS index score and motor function as measured with time required to complete TUG (r = −0.644, p < 0.001), number of steps to complete TUG (r = −0.571, p < 0.001), 10-m walk time (r = −0.637, p < 0.001), and 10-m walk steps (r = −0.588, p < 0.001). The authors also found a positive linear correlation between mean ALPS index score and MMSE score (r = 0.416, p = 0.001). Simple linear regression showed a significant effect of diagnosis (B = −0.39, p < 0.001, R2 = 0.459), female sex (B = 0.232, p = 0.002, R2 = 0.157), and Evans index (B = −4.151, p < 0.001, R2 = 0.559) on ALPS index. Multiple linear regression, including diagnosis, sex, and Evans index score, showed a higher predictive value (R2 = 0.626) than analysis of each of these factors alone.

CONCLUSIONS
The ALPS index, which was significantly decreased in iNPH patients, could serve as a marker of disease severity, both clinically and in terms of neuroimaging. However, it is important to consider the significant influence of biological sex and ventriculomegaly on the ALPS index, which raises the question of whether the ALPS index solely reflects glymphatic function or if it also encompasses other types of injury. Future studies are needed to address potential confounding factors and further validate the ALPS method.
Zabramski classification in predicting the occurrence of symptomatic intracerebral hemorrhage in sporadic cerebral cavernous malformations
Authors: Wang Jie , Yu Qi-Feng , Huo Ran , Sun Ying-Fan , Jiao Yu-Ming , Xu Hong-Yuan , Zhang Jun-Ze , Zhao Shao-Zhi , He Qi-Heng , Wang Shuo , Zhao Ji-Zong , Cao Yong 
Published: September 2023

OBJECTIVE
The authors aimed to investigate the evolutionary characteristics of the Zabramski classification of cerebral cavernous malformations (CCMs) and the value of the Zabramski classification in predicting clinical outcome in patients with sporadic CCM.

METHODS
This retrospective study consecutively included cases of sporadic CCM that had been untreated from January 2001 through December 2021. Baseline and follow-up patient information was recorded. The evolution of the Zabramski classification of a sporadic CCM was defined as the initial lesion type changing into another type for the first time on MRI follow-up. The primary outcome was the occurrence of a hemorrhage event, which was defined as a symptomatic event with radiological evidence of overt intracerebral hemorrhage.

RESULTS
Among the 255 included cases, 55 (21.6%) were classified as type I CCM, 129 (50.6%) as type II CCM, and 71 (27.8%) as type III CCM, based on initial MRI. During a mean follow-up of 58.8 ± 33.6 months, 51 (20.0%) patients had lesion classification transformation, whereas 204 (80.0%) patients maintained their initial type. Among the 51 transformed lesions, 29 (56.9%) were type I, 11 (21.6%) were type II, and 11 (21.6%) were type III. Based on all follow-up imaging, of the initial 55 type I lesions, 26 (47.3%) remained type I and 27 (49.1%) regressed to type III because of hematoma absorption; 91.5% of type II and 84.5% of type III lesions maintained their initial type during MRI follow-up. The classification change rate of type I lesions was statistically significantly higher than those of type II and III lesions. After a total follow-up of 1157.7 patient-years, new clinical hemorrhage events occurred in 40 (15.7%) patients. The annual cumulative incidence rate for symptomatic hemorrhage in all patients was 3.4 (95% CI 2.5–4.7) per 100 person-years. Kaplan-Meier survival analysis showed that the annual cumulative incidence rate for symptomatic hemorrhage of type I CCM (15.3 per 100 patient-years) was significantly higher than those of type II (0.6 per 100 patient-years) and type III (2.3 per 100 patient-years).

CONCLUSIONS
This study suggests that the Zabramski classification is helpful in estimating clinical outcome and can assist with surgical decision-making in patients with sporadic CCM.
Normal growth curve of choroid plexus in children: implications for assessing hydrocephalus due to choroid plexus hyperplasia
Authors: Hashimoto Hiroaki , Takemoto Osamu , Nishimoto Keisuke , Moriguchi Gento , Nakamura Motoki , Chiba Yasuyoshi 
Published: September 2023

OBJECTIVE
Pediatric hydrocephalus requires evaluation while accounting for growth of the intracranial structures, but information on choroid plexus growth in children is lacking. This study aimed to create normal growth curves for intracranial volume, choroid plexus volume, and lateral ventricles volume. Additionally, the authors aimed to objectively assess the degree of hydrocephalus caused by choroid plexus hyperplasia (CPH) and to examine the impact of surgical procedures.

METHODS
This retrospective study analyzed the head CT scans of pediatric patients with minor head trauma treated at Osaka Women’s and Children’s Hospital between March 2006 and May 2023. The study segmented and calculated intracranial, choroid plexus, and lateral ventricles volumes. The study also calculated the correlation coefficients among these 3 parameters. Patients aged 0 to 10 years were divided into 15 age-related clusters, and mean ± SD values were calculated for each cluster. Growth curves were created by plotting mean values sequentially. Volume obtained from patients with CPH were z-normalized using mean and SD values and compared.

RESULTS
A total of 229 CT scans (94 from females) were analyzed, and positive correlations were observed among intracranial volume, choroid plexus volume, and lateral ventricles volume, with the strongest correlation between the choroid plexus and lateral ventricles volumes. The growth rate of intracranial volume was rapid until approximately 20 months of age, while those of choroid plexus volume and lateral ventricles volume increased rapidly until approximately 1 year of age. Subsequently, choroid plexus volume and lateral ventricles volume plateaued at 1.5 ml and 10 ml, respectively. Three patients with CPH were enrolled and quantitatively evaluated on the basis of the z-normalized volume. Notable abnormal volumes of the choroid plexus (range z-normalized values 24.11–51.17) and lateral ventricles (46.78–122.36) were observed. In 2 patients, improvements in the z-normalized values of intracranial volume and lateral ventricles volume were observed after surgical interventions. Additionally, in 1 patient, choroid plexus volume was reduced by approximately 24% (range z-normalized values 51.17–38.93) after bilateral endoscopic plexus coagulation.

CONCLUSIONS
This study provides normal growth curves for intracranial volume, choroid plexus volume, and lateral ventricles volume. Knowledge of these normal values holds the potential for objective assessment of abnormal values associated with hydrocephalus and choroid plexus diseases such as CPH.
Strategies of Controlling Iron Deficiency among Pregnant Women in the Peripheral Health Zones of Kinshasa, Democratic Republic of the Congo
Authors: Tamundele Luhunu , Kasongo Yumba , Mufeng Mutinsumu , Mbokoso Mwanamoki , Mbenza Luvandu , Mugangu Bashimbe , Nsutier Oscar K. , Tshiama Claudine , Bongo Gédéon N. 
Published: September 2023

Anemia is the most widespread nutritional problem in the world. Its incidence rate is higher in South Asia and sub-Saharan Africa, where it affects a large proportion of women and children. The problem is accentuated where intestinal parasitic infection and malaria are common and this increases the morbidity and mortality rate. The current study attempted to evaluate the effectiveness of strategies involved in the control system of iron deficiency anemia in pregnant women. This study comprised of a quantitative, cross-sectional, and analytical design. Two reference health structures were chosen, namely Kimbanseke General Reference Hospital and Kinkole General Reference Hospital. The sample size consisted of 250 pregnant women. The data collection involved hemoglobin, thick drop, and stool analysis to assess the hematological and health status of surveyed pregnant women. Moreover, a questionnaire was used to collect socio-demographic data. The chi-square test was used to compare the variables and logistic regression was used to determine the effectiveness of applied strategies in order to control iron deficiency. Respondents were assured about the confidentiality of their responses and interviews were conducted in a secluded setting. The findings showed that the predominant age group was 20-24 years (34.0%), while most respondents were in the second semester of pregnancy (49.6%). Furthermore, most respondents had a secondary education (69.2%), their main activity was selling (47.2%), and most of them were married (84.0%). The level of hemoglobin was less than 11g/dl in most of the respondents (55.6%), while 66% were multigravida with the space between pregnancy of 12-24 months (57.8%). The stool analysis of most respondents showed the presence of yeast (24%), although the presence of some parasites were observed as well. For the thick drop, most respondents were diagnosed with malaria (77.6%). The iron supplementation, deworming, and counseling during the antenatal sessions proved effective against iron deficiency anemia. Given the seriousness of the situation in pregnant women, it is necessary that these strategies of effectiveness must be applied for a good management of anemia.
¿Qué es una revista depredadora?
Authors: Escobar Andres 
Published: September 2023

En la comunidad académica existen consensos con relación a la existencia en el mundo editorial de revistas que aprovechan el modelo de acceso abierto con fines de lucro, sin el cumplimiento de los estándares mínimos de publicación científica (Bertoglia y Aguila, 2018; Escobar, 2019a; Escobar, 2019b), Cobey et al, 2019). Esto es particularmente relevante dados los diferentes incentivos existentes entre países, sean estos a nivel individual o incluso institucional. La búsqueda de recursos para financiar las investigaciones, tanto a nivel nacional como internacional, ha generado una alta competencia entre individuos e instituciones.

Hoy en día, en el mundo científico se evalúa la productividad científica a partir de diferentes métricas cuantitativas, tales como el numero individual de publicaciones, las citaciones, índices que reflejan distintas combinaciones, factores de impacto, número de patentes, entre otros (Carpenter et al 2014). Lo anterior determina el prestigio académico individual como también el prestigio científico de las instituciones, las cuales además son evaluadas por diferentes entidades a partir de métricas de su productividad académica.