bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing a Screen-Clean-Hydrate bundle of care for improving swallow screening, oral health and hydration in acute stroke: Protocol for a Type 2 hybrid-effectiveness pre-post study
Authors: Murray Joanne , Gunasekaran Sulekha , Doeltgen Sebastian , George Stacey , Harvey Gillian 
Published: May 2023

Abstract
Background
Stroke clinical guidelines recommend care processes that optimise patient outcomes and minimise hospital-acquired complications. However, compliance audits and surveys illustrate that recommended care is not always consistently or thoroughly implemented. This paper outlines the methods for a study implementing and evaluating a new bundle of care, named Screen-Clean-Hydrate, aiming to improve compliance with stroke guidelines in the areas of swallow screening, oral healthcare and hydration.
Methods
The study is a pre-post Type 2 Hybrid Effectiveness/Implementation design with an embedded process evaluation. The integrated-Promoting Action on Research Implementation in Health Services (iPARIHS) framework will be used to guide the study design, conduct and evaluation. The study will be conducted in two acute stroke units in a capital city of Australia. Screen-Clean-Hydrate bundles together recommendations from the Australian Clinical Guidelines for Stroke Management and supplements these with evidence-informed best practice from the literature for: swallow screening within four hours of presentation to hospital (Screen); oral health assessment and delivery of routine oral care (Clean); and hydration assessment and management (Hydrate). Clinical effectiveness will be measured by rates of ICD-10AM coded hospital-acquired complications and proxy measures of cost (length of stay, procedure costs) for 60 patient participants pre- and post-implementation. Implementation outcomes will focus on acceptability, feasibility, uptake and fidelity, and identification of barriers and enablers to implementation through staff interviews, medical record audits and researcher field notes.
Discussion
Bundles of health care processes to target hospital-acquired complications have successfully been implemented in other areas of healthcare. Screen-Clean-Hydrate bundles together and makes explicit the recommendations from the Australian clinical stroke guidelines for swallow screening, oral health and hydration and their importance for functional recovery and avoidance of hospital-acquired complications. Due to its design as a hybrid effectiveness/implementation study, once completed, the study will provide information on both intervention and implementation effectiveness, including details of successful and unsuccessful multidisciplinary implementation strategies. This will inform a larger multi-site effectiveness/implementation trial and promote upscale across other settings for improved compliance with stroke guidelines and therefore stroke outcomes.
The benefit of a glass die relative to a metal die in microforming
Authors: Huang Kuo Ming , Chang Chuan-Hsiang , Ramanuel Joseph 
Published: May 2023

Abstract

This study investigated the application of a glass die in the forming of microproducts. Lower surface friction and better material flow are achieved in the microforming process when using a glass die than when using a metal die. In contrast to metal dies, glass dies need not repeatedly polished or coated to maintain their smooth surface. Moreover, lubrication is required in the microforming process in the case of a metal die but not glass die. We performed simulated and experimental double-cup extrusion tests on glass dies and found that glass dies affect the direction of material flow. Overall, this study demonstrates that a larger contact area between the billet and the die, a lower friction force, better material flow at specific locations, and a smaller difference between internal and external flows can be achieved when using a glass die in the microforming process than when using a metal die in this process.
Water use of a super high density olive orchard submitted to regulated deficit irrigation in Mediterranean environment over three contrasted years
Authors: Ferrara Rossana , Bruno Maria Roberta , Campi Pasquale , Camposeo Salvatore , Carolis Gabriele , Gaeta Liliana , Martinelli Nicola , Mastrorilli Marcello , Modugno Anna Francesca , Mongelli Teresa , Piarulli Mariagrazia , Ruggieri Sergio , Rana Gianfranco 
Published: May 2023

Abstract

The measurement of transpiration at the field level is a challenging topic in crop water use research, particularly for orchards. The super high density olive orchard system is in great expansion all over the world, so these investigations are necessary to assess the trees water use under different irrigation techniques. Here, transpiration at plant and stand scales was measured using the sap flow thermal dissipation method, in an olive orchard (cv. “Arbosana”) subjected to full and regulated deficit irrigation (RDI) with a withholding irrigation period under Mediterranean climate (southern Italy). The measurement method was used after specific calibration and correction for wound effect, azimuthal and gradient errors. Water use efficiency (WUE) and water productivity (WP) were determined over three complete growth seasons (2019–2022). The seasons were submitted to highly contrasted weathers. Measurements of stem water potential and stomatal conductance showed that the RDI trees were under mild-moderate water stress only during the withholding irrigation period. Results showed that seasonal Tr was not significantly different in the two treatments in all seasons (249 and 267 kgm− 2, 249 and 262 kgm− 2, 231 and 202 kgm-2 for FI and RDI in the three seasons, respectively) and that WUE was greater in RDI treatment without any impact on yield. The main conclusion is that, when the available water in the soil is limited, olive trees decrease transpiration under any atmospheric conditions, but when the water in the soil is amply available, drought conditions lead to a decrease in tree transpiration.
A qualitative investigation on experiences concerning breast cancer-related lymphedema in the coastal area of Fukushima, Japan in the long-term aftermath of the 2011 triple disaster
Authors: Kobayashi Naomi , Ozaki Akihiko , Kotera Yasuhiro , Kaneda Yudai , Bhandari Divya , Takamatsu Katsumori , Kasai Tadashi , Arai Megumi , Takasaki Junko , Saito Hiroaki , Sawano Toyoaki , Kanemoto Yoshiaki , Sato Hiroyuki , Tsubokura Masaharu , Kurokawa Tomohiro , Tachibana Kazunoshin , Wada Masahiro , Tanimoto Tetsuya , Ohtake Tohru , Ejiri Tomozo , Shimmura Hiroaki , Kanzaki Norio 
Published: May 2023

Abstract
Disasters could jeopardize breast cancer care, and the 2011 Japan’s triple disaster (earthquake, tsunami, and nuclear accident) has been no exception. However, the information is lacking regarding its details, including that concerning breast cancer-related lymphedema (BCRL). We aimed to explore the process of becoming aware of BCRL among the local patients and the problems faced and the support needed by them. We also aimed to clarify any effects of the 2011 disaster on the experiences related to lymphedema among the target population. Patients who developed BCRL following the breast cancer treatment were recruited in Iwaki City, a municipality located in the southern coastal Fukushima (N = 16). In-depth semi-structured interviews were conducted face-to-face, and the obtained data were appraised with thematic analysis. Five themes related to BCRL were identified: 1) process of becoming aware of BCRL, 2) troubles or worries/concerns due to BCRL, 3) information source regarding BRCA management, 4) strategies to cope with BCRL, 5) adverse impacts of the 2011 disaster on BCRL management. This qualitative analysis clarified the five themes related to BCRL. The themes except for the disaster context were in line with the previous studies conducted in the non-disaster context. There were limited but non-neglectable adverse impacts of the 2011 disaster on the long-term local BCRL management.
Development of Pistia spp.- Based Biochar Filter for the Treatment of Industrial Wastewater: A Green Approach
Authors: Jayathilake Pramod Ihara , Manage Pathmalal Marakkala , Idroos Fathima Sumaiya 
Published: May 2023

Abstract

Biochar (BC) has a viable wastewater treatment agent. The invasive aquatic plant Pistia spp. was used to produce BC. Activated and non-activated BC samples were individually incorporated into a filter. Water quality parameters were measured in the experiment before and after treatment. The control filter was developed using only sand and gravel. The effect of particle sizes of BC (65-125mm and 125-250mm) and repeated treating process on treatment efficiency were carried out as optimization studies for activated BC filter. The filter unit containing activated BC showed a higher treatment efficiency. The results of the optimization study revealed that, the BC integrated filter units could be used to treat wastewater for three consecutive cycles. The BC's small particle size (65-125mm) recorded the highest treatment. This particle size showed turbidity reduction by 99.72 %. It was found that reduction of Total Phosphates, Ammoniacal Nitrogen, TSS, COD, Nitrate, BOD5 and TKN by 97.82 %, 91.49 %, 88.38 %, 88.18 %, 87.44 %, 84.38 %, and 84.38 % respectively. BC derived from Pistia spp. is a promising adsorbent for wastewater treatment. Findings of the study showed a long-term green wastewater treatment method that makes effective use of invasive aquatic plants.
Aspirin use increases risk of immune-related adverse events in cancer patients treated with immunotherapy: analysis of the FAERS database
Authors: yang huaju , Liu Zheran , Li Ruidan , Huang Rendong , Peng Xingchen 
Published: May 2023

Abstract
Background The promise of immunotherapy in cancer treatment is tempered by the occurrence of immune-related adverse events (irAEs). Many patients undergoing immunotherapy also take aspirin, but the impact of aspirin on irAEs is not well understood. This study aimed to investigate the association between aspirin use and irAEs in patients receiving immunotherapy.Methods This study analyzed adverse reaction data associated with the use of immune checkpoint inhibitors (ICIs) in the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database, from the approval date of each drug until October 1, 2022. Multivariate logistic regression was employed to assess the effect of aspirin use on irAEs in patients receiving ICIs. .Results The analysis included 123,104 patients who underwent immunotherapy, of whom 5359 also received aspirin. The results showed that aspirin use was associated with an increased risk of irAEs in the pan-cancer analysis, and this association was more pronounced in specific cancer types such as lung cancer, mesothelioma, and pancreatic cancer. Additionally, aspirin use was correlated with an elevated risk of certain irAEs such as anaemia, colitis, myocarditis, myositis, pancreatitis, pericarditis and pneumonitis.Conclusions These findings suggest that aspirin exposure is associated with a higher risk of irAEs in patients undergoing cancer immunotherapy. Moreover, different cancer types and the ICI types can also impact irAEs.
Transcriptome analysis of harvested okra (Abelmoschus esculentus L.) in response to chilling stress
Authors: Zhu Zhi-peng , Yu Jian-xiang , Tang Xin-hui , Zhu De-wei , Xiong Ai-sheng , Sun Miao 
Published: May 2023

Abstract

Okra (Abelmoschus esculentus L.) is a novel vegetable with high nutritional and medicinal values. However, as a cold-sensitive crop, okra pods are susceptible to chilling injury (CI) during cold chain packaging and transportation, and the molecular mechanism of postharvest okra pods in response to chilling stress has not been elucidated. In this study, after storage at 4 °C for 15 d, okra pods from ‘Hokkaido’ exhibited progressively worseningCI symptoms, as well as continuously elevated CI index and CI incidence. Transcriptomic analysis showed that during low-temperature storage, many unigenes were activated by chilling stress and were mainly enriched in ‘Signal transduction’, ‘Amino acid metabolism’, and ‘Carbohydrate metabolism’. Further studies showed that the biosynthesis and signaling mechanism of ethylene (ETH) and abscisic acids (ABA) was activated by chilling stress, which induced reactive oxygen species (ROS) over-accumulation and up-regulated genes related to membrane lipid peroxidation. Chilling stress also activated genes involved in chlorophyll degradation and reduced chlorophyll a, chlorophyll b, and total chlorophyll content. In addition, 156 transcription factors (TFs) belonging to 12 families were identified from transcript databases. This study gained insight into the chilling transcriptional response mechanism of postharvest okra pods, which will contribute to cold chain management and molecular breeding of okra.
Impact of Hemodialysis on Efficacies of the Antiplatelet Agents in Coronary Artery Disease Patients Complicated with End‑Stage Renal Disease
Authors: Ye Zekang , Ullah Inam , Wang Qin , Lin Qingxia , Wu Tianyu , Yang Mingwen , Fan Yuansheng , Dong Zhou , Wang Tong , Teng Jianzhen , Hua Rui , Tang Yingdan , Li Yule , Gong Xiaoxuan , Yuan Liang , Li Chunjian 
Published: May 2023

Abstract
Background It is controversial whether hemodialysis affects the efficacy of the antiplatelet agents. We aimed to investigate the impact of hemodialysis on efficacies of the antiplatelet agents in coronary artery disease (CAD) patients complicated with end‑stage renal disease (ESRD).
Methods 86 CAD patients complicated with ESRD requiring hemodialysis were consecutively enrolled. After 5-day treatment with aspirin and clopidogrel or ticagrelor, the platelet aggregations induced by arachidonic acid (PLAA) or adenosine diphosphate (PLADP), and the P2Y12 reaction unit (PRU) were measured before and after hemodialysis. The propensity matching score method was adopted to generate a control group with normal renal function from 2439 CAD patients.
Results In patients taking aspirin, the PLAA remained unchanged after hemodialysis. In patients taking clopidogrel, the PLADP (37.26 ± 17.04 vs. 31.77 ± 16.09, p = 0.029) and corresponding clopidogrel resistance (CR) rate (23 [48.9%] vs.14 [29.8%], p = 0.022) significantly decreased after hemodialysis, though PRU remained unchanged. Subgroup analysis indicated that PLADP significantly decreased while using polysulfone membrane (36.8 ± 17.9 vs. 31.1 ± 14.5, p = 0.024). In patients taking ticagrelor, PLADP, and PRU remained unchanged after hemodialysis. ESRD patients had higher incidences of aspirin resistance (AR) and CR compared to those with normal renal function (AR: 16.1% vs. 0%, p = 0.001; CR: 48.4% vs. 24.8%, p = 0.024).
Conclusion Hemodialysis does not have negative effect on the efficacies of aspirin, clopidogrel and ticagrelor in ESRD patients with CAD. On the contrary, clopidogrel response may be improved while using the polysulfone membrane during hemodialysis. ESRD patients have higher incidences of AR and CR compared with those with normal renal function.
Trial registration ClinicalTrials.gov Identifier: NCT03330223.
Temporal and small-scale spatial variation in distribution, abundance, and reproduction of Australian hijiki analogues in southwest Victoria
Authors: Vairo Daniel , Bellgrove Alecia , Biancacci Cecilia 
Published: May 2023

Abstract

Exploration of Australian fucoids for aquaculture production has been limited, despite globally high regional diversity and endemism. Sargassum fusiforme (hijiki in Japanese) is amongst the most highly valued seaweeds worldwide for human consumption, but concerns about high arsenic concentrations limit importation into countries with strict safe-food regulations and standards. We investigated the temporal and small-scale spatial variation in distribution, abundance, growth (estimated by changes in length), reproduction (estimated from the number of fertile conceptacles per receptacle and/or percentage of reproductive branches) and biofouling of two Australian sargassaceous fucoids, Cystophora torulosa and Caulocystis uvifera, that show promise as low-arsenic alternatives to hijiki. Temporal variation was assessed by seasonal surveys in a single year, in which small-scale spatial variation was assessed at a single site for each species, comparing high-shore and low-shore for intertidal C. torulosa and distance from the shore for subtidal C. uvifera. For C. torulosa, no significant variation in distribution, abundance or reproduction was observed; however, growth peaked in winter. Moreover, biofouling of C. torulosa was minimal throughout the study. In contrast, significant temporal variation was observed for C. uvifera with peaks in growth and reproduction in spring, and biofouling in summer. In both species, reproductive output increased with thallus length. Whilst both species might be promising Australian hijiki analogues, the temporal and spatial consistency in reproduction and minimal biofouling may render cultivation of C. torulosa more practical for successful commercialisation than for C. uvifera. However, generality of our findings should be assessed at larger spatial and temporal scales.
Pediatric supracondylar humeral fractures： a safe entry zone of medial pinning based on intraoperative fluoroscopy to avoid iatrogenic ulnar nerve injury
Authors: Liu Hongbin , Zhu Yong , Hu Yi , Li Kaihu , Long Haitao , Lin Zhangyuan , Zhao Ruibo , Sun Buhua , Zhao Shushan , Cheng Liang 
Published: May 2023

Abstract
Background
For children with supracondylar humeral fractures (SHFs), iatrogenic ulnar nerve injury resulting from medial pinning remains a challenge for orthopedic surgeons. This study aims to explore a safe medial pinning zone and assess its efficacy.
Methods
First, the radiographic images of a healthy elbow were reconstructed and mapped by E3d software to display the safe medial pinning zone we summarized. Second, all the pediatric SHF cases treated by our team between May 2014 to May 2020 were retrospectively reviewed to evaluate the safety and efficacy of the pinning zone. Furthermore, we proposed a hand gesture to fast locate the safe medial pin insertion point.
Results
On the anteroposterior (AP) view, the upper 1/2 part of the slope line segment we defined was safe since the ulnar nerve traversed the ulnar groove at the lower 1/2 part. On the lateral view, the diamond zone we defined was a safe entry zone. In the retrospective study, 134 SHF cases were included and divided into two groups. In group A (74 cases), the medial Kirschner wire (K-wire) was inserted from the safe zone at both AP and lateral views, while in group B (60 cases) the medial pinning point was beyond the safe entry zone. The incidence of iatrogenic ulnar nerve injury in group A was significantly lower than in group B (P < 0.01). Moreover, the exploration and neurolysis of the ulnar nerve were performed in patients involving postoperative ulnar nerve dysfunction. A left-hand gesture by the surgeon during operations could help to fast locate the safe insertion point of medial pins.
Conclusion
Medial pinning from the safe entry zone based on intraoperative fluoroscopy is an easy, reliable, and reproducible technique to avoid iatrogenic ulnar nerve injury in children with SHFs.
Investigation of optical properties and chemical structure of Nd2O3 nanoparticles deposited on NaX zeolite powder using plasma focus device
Authors: Seyedhabashi Mir Mohammad Reza , Hosseinpour Hesham , Noori Ehsanollah 
Published: May 2023

Abstract

In this study, nanoparticles of neodymium oxide were deposited on NaX zeolite powder using a 5.3 kJ Mather‒type plasma focus device. The NaX zeolite samples were exposed to the 10, 15, and 20 shot numbers of the plasma focus device at a distance of 14 cm from the anode tip and 0 angular positions with respect to the anode axis. Parent NaX zeolite and NaX:Nd composites with different Nd2O3 percent weights were characterized using different techniques such as; XRF, XRD, SEM, FT‒IR, and UV‒vis. It was shown that the amount of Nd2O3 in the samples increases with increase of the shot number. It was also found from the results that variations in amount of Nd2O3 can have significant effects on the degree of the crystallinity and optical properties of final products such as refractive index, band gap energy, dielectric constant, and absorption coefficients.
Basketball Action Recognition Based on the Combination of YOLO and a Deep Fuzzy LSTM Network
Authors: Khobdeh Soroush Babaee , Yamaghani Mohammad Reza , Sareshkeh Siavash Khodaparast 
Published: May 2023

Abstract
The ability to identify human actions in uncontrolled surroundings is important for human-computer interaction (HCI), especially in the sports areas to offer athletes, coaches, and analysts valuable knowledge about movement techniques and aid referees in making well-informed decisions regarding sports movements. Noteworthy, recognizing human actions in the context of basketball sports remains a difficult task due to issues like intricate backgrounds, obstructed actions, and inconsistent lighting conditions. Accordingly, a method based on the combination of YOLO and deep fuzzy LSTM network is proposed in this paper. YOLO is utilized for detecting players in the frame and the combination of LSTM and fuzzy logic is used to perform the final classification. The reason behind using LSTM along with fuzzy logic refers to its inability in coping with uncertainty which led to the creation of a more transparent, interpretable, and accurate predictive system. The proposed model was validated on SpaceJam and Basketball-51 datasets. Based on the empirical results, the proposed model outperformed all baseline models on both datasets which obviously confirms the priority of our combinational model for basketball action recognition.
Characteristics and Services Utilization by Users of Home Care Services in Catalonia: A Retrospective Cohort-Based Study of a Social Program for Dependent Individuals
Authors: Contel Joan C. , Vila Anna , Vela Emili , Santaeugènia Sebastià J. , Amblàs-Novellas Jordi , Barbeta Conxita , Hilarión Pilar , Plaza Aina , Piera-Jiménez Jordi 
Published: May 2023

Abstract
Introduction:
Home Care Services (HCS) for care-dependent individuals enable their independent lives at home. We aimed to characterize users and evaluate the impact of social HCS for dependent individuals.
Methods:
Retrospective study including all social HCS recipients for individuals with the official recognition of dependency from Catalonia using 2018–2019 data from the Autonomy and Dependency Care System and the Catalan Health Surveillance System. Variables were social and healthcare services utilization and expenditure. HCS recipients were compared to non-recipients. Changes in services utilization and expenditure before and after HCS were estimated.
Results:
The 48,885 individuals who received HCS in 2019 were mostly >84 years, women, and had moderate dependency. Recipients’ prevalence was higher among low-/very-low-income individuals. HCS users had a higher morbidity burden than non-recipients with increased healthcare service utilization and associated expenditures. After HCS initiation, Telecare, day center, and most healthcare services utilization increased. Social and healthcare service-associated expenditures increased from a mean of 535 to 867 €/individual/month after HCS initiation, mostly due to HCS.
Conclusions:
Social HCS dependency recipients were overall very old, with moderate dependency, low-income, high morbidity, and intensive use of healthcare services. HCS is associated with increased social service-associated expenditures and modestly decreased healthcare-associated expenditures.