bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping ultra-processed foods (UPFs) in India: A formative research to adapt and inform a UPF consumption screening tool for India
Authors: Ghosh-Jerath Suparna , Singh Meenu , Kumar Gaurika , Bhambra Inderdeep Kaur , Kohli Sahiba , Khandpur Neha , Leite Fernanda H. M. , R K. Srinath 
Published: July 2023

Abstract

Background
Increased consumption of ultra-processed foods (UPFs) which are usually high in salt, sugar, fats, preservatives and additives are associated with diet-related non-communicable diseases. In India, there are no standard criteria for identifying UPFs that are similar to Nova food classification (based on extent and purpose of industrial processing). Scientific literature in India classifies foods as unhealthy based on the presence of excessive amounts of specific nutrients which makes it difficult to distinguish UPFs from other commercially available processed foods. The purpose of this paper is to map UPFs in the Indian food market and assess their consumption by Indian population.
Methods
A literature review and online grocery market survey were conducted to map the types of UPFs in the Indian food market, their availability and consumption. In online grocery market survey, the ingredient list of the foods provided on their label were scrutinized for the presence of ultra-processed ingredients. All UPFs identified were free-listed, followed by saliency analysis to understand preferred UPFs by Indian consumers. Findings were then triangulated to develop Indian UPF sub-categories to inform a UPF screening tool.
Results
UPFs lack uniform definition in India; hence proxy names such as junk-foods, fast-foods, ready-to-eat foods, instant-foods, processed-foods, packaged-foods, high-fat-sugar-and-salt foods are used for denoting UPFs. Our data showed that the current literature from India does not clearly differentiate between processed culinary ingredients (Nova food group 2), processed foods (Nova food group 3) and UPFs (Nova food group 4). Saliency analysis showed sugar-sweetened beverages (e.g. sodas and cold-drinks) are the most preferred UPFs while frozen ready-to-cook/eat foods (e.g. chicken nuggets and frozen kebabs) are least preferred. Online grocery market survey also revealed that traditional recipes are transitioning into UPFs. Based on our data, a screening tool for UPF consumption consisting of twenty-four UPF sub-categories were listed and divided into three sections: drinks and beverages, ready-to-eat and ready-to-cook foods was developed.
Conclusion
India needs to adapt Nova food classification and systematically define Indian food categories based on level of processing, followed by an assessment of the extent of UPF consumption in India. Clear policy guidelines and regulations around UPF consumption should be devised to address the impact of UPF consumption on NCDs.
Attitudes of vaccination workers toward COVID-19 vaccination in patients with chronic liver disease
Authors: Tang Yong-Zhi , Huang Chun-Lian , Ling Xiao-Qing , Ye Xiao-Hong , Xu Guang-Ming , Ying Chen-Qian , Deng Jing-Shan , Tung Tao-Hsin , Zhu Jian-Sheng 
Published: July 2023

Abstract
Objectives
Vaccination workers play an important role in the acceptance of various vaccines in patients with chronic liver diseases. We mainly investigated the attitude of vaccination workers toward COVID-19 vaccination in patients with chronic liver disease.
Methods
An anonymous, population-based, cross-sectional online survey were completed by 721 out of 1008 (71.5%) vaccination workers from July 1st to July 14th, 2022, in patients with chronic liver disease in Taizhou, China. The data were uploaded to Wen-Juan-Xing, one of the largest online platforms for collecting survey data.
Results
We found that only 51.9% of vaccination workers recommended all chronic liver diseases vaccinations. 81% of vaccination workers fully recommended vaccination in patients with fatty liver and chronic hepatitis B, while 53.1% of them fully recommended in patients with cirrhosis and liver cancer. Logistic regression analysis showed that vaccination workers who had undergone systematic training were more likely to recommend that patients with four chronic liver diseases get vaccinated (OR: 1.59; 95% CI: 1.05–2.43, p = 0.030). Vaccination workers that believed it is safe to vaccinate against patients with four chronic liver diseases were likely to recommend (OR: 8.12; 95% CI: 1.84–35.88, p = 0.006).
Conclusion
Vaccination workers who hold a positive attitude towards recommending vaccination for patients with chronic liver disease needs to be improved. Strengthening the training of vaccination workers could improve vaccine immunization coverage.
Taxonomy and molecular phylogeny of black flies (Diptera: Simuliidae) in Africa and Europe by using mitochondrial Cox1 and nuclear ITS2 markers
Authors: Kamtsap Pierre , Ngoufo Flore Nguemaïm , Ekale David , Yilak Abebual , Schnell Rahel , Akafyi Danlami Elisha , Garbi Mohamed , Kamgno Joseph , Djeunga Hugues C. Nana , Fouamno Henri Lucien Kamga , Paguem Archile , Renz Alfons 
Published: July 2023

Abstract
Background
Black flies are present worldwide and are represented by 2,348 species (2,331 living species and 17 fossils) classified under 31 genera. In Africa, 124 species of black flies have been described, of which 55 are known to occur in Cameroon. However, these identifications are all based on morphology and, for S. damnosum only, on cytotaxonomic studies. Little has yet been achieved by modern molecular genetic techniques. In this study, we have applied DNA-based techniques to investigate the diversity and evolution of Simulium flies to improve vector control.
Methods
Simulium larvae and pupae were randomly collected from various Simulium breeding sites in rivers from five countries (Cameroon, Ethiopia, Tunisia, Nigeria and Germany). Adult Simulium flies were caught on humans in Cameroon, Nigeria and Ethiopia. Pupal gills were examined and photographed in a drop of polyvinyl-lactophenol. Genomic DNA was extracted and the CoxI and ITS2 genes were targeted by the polymerase chain reaction. The amplification products were sequenced and trees were drawn. Sequences were refined using Geneious Prime and evolutionary analyses were conducted in Mega-X 10.5.
Results
More than 54 sample collections were included in this study, of which about 1,000 individual larvae, pupae or adult flies from the various sites were examined. Twenty-five species were identified on the basis of their morphology and DNA-sequencing: Simulium damnosum s.l.; S. unicornutum; S. katangae; S. hisurtum; S. cervicornutum; S. schoutedeni; S. alcocki; S. dentulosum (A; B and C); S. ruficorne; S. hargreavesi v. medusaeforme; S. hargreavesi; S. adersi; S. pseudequinum; S. (Eusimulium) latipes; S. (Odagmia) ornatum; S. (Wilhelmia) equinum; S. vorax; S. nigritarsis duboisi; S. kenyae; S. velutinum; S. aureum; S. angustipes; S. bovis; S. tuberosum; S. rodhaini). Sequences of the previously undescribed species are deposited in GenBank.
Conclusions
We show, for the first time, the relationship between the morphology and molecular data of some black flies from Cameroon, Ethiopia, Nigeria, Tunisia and Germany. These data are important for understanding the transmission and life-cycles of Simulium-borne parasites: Moreover, knowledge concerning the various members of the S. damnosum complex in the rainforest and savannah is a prerequisite for the successful elimination of the parasite Onchocerca volvulus in Africa.
Co-Culture of Acinetobacter johnsonii and Shewanella putrefaciens contributes to ABC transporter that impacts cold adaption in aquatic food storage environment
Authors: Wang Xin-Yun , Yan Jun , Xie Jing 
Published: July 2023

Abstract
Background: Acinetobacter johnsonii and Shewanella putrefaciens were identified as specific spoilage organisms in aquatic food. The interactions among specific spoilage organisms under cold stress have a significant impact on the assembly of microbial communities, which play crucial roles in spoilage and cold adaptation processes. The co-culture of Acinetobacter johnsonii and Shewanella putrefaciens under cold stress was determined at protein and metabolism levels, which remain largely unknown, leading to a poor understanding of the interactions between A. johnsonii and S. putrefaciens in the mediated cold adaptation mechanism.
Results The results of 4D-quantitative proteomic analysis showed that co-culture of A. johnsonii and S. putrefaciens responds to low temperatures through ABC transporter proteins, resulting in phospholipid transport and inner membrane components. Based on KEGG enrichment analysis, SapA and FtsX proteins were significantly up-regulated, while LolC, LolD, LolE, PotD, PotA, PotB, PotC proteins were significantly down-regulated, respectively. Furthermore, data from metabolomeassays revealed that metabolites of Glutathione, Spermidine/Putrescin were significantly up-regulated, while metabolites of Arginine/Lysine/Ornithine were significantly down-regulated involved in ABC transporter metabolism. The co-culture of A. johnsonii and S. putrefaciens under cold stress significantly increased the activities of Alkaline phosphatase (AKP) and ATPase, resulting in substantial changes in membrane properties in response to cold stress. The scanning electron microscopy (SEM) and transmission electron microscope (TEM) results showed that co-culture in A. johnsoniiand S. putrefaciens surface combined with the presence of the leakage of intracellular contents, suggesting that the bacteria was severely damaged and wrinkled to absorb metabolic nutrients and adapt to cold temperatures.
Conclusions: Our study sheds new light on the significance of co-culturing A. johnsonii and S. putrefaciens under cold stress, as evidenced by proteomic and metabolomic analyses, as well as ultramicroscopic morphology. Based on the co-culture of A. johnsonii and S. putrefaciens, the ABC transporter exhibited the ability to enhance cold adaptation and facilitate microbial protein and metabolic interactions in the aquatic food storage environment.
Cost Effective Analysis and role of Liv-52 and Ursodeoxycholic acid in Anti-Tubercular induced Hepatotoxicity: A Randomized Open Controlled Monocentric Study
Authors: Reshu Kumari , Murti Krishna , Meenakshi Sarasa , Kumar Nitesh , Dhingra Sameer , Ravichandiran V , Vishwas Gopal , Pandey Krishna 
Published: July 2023

Abstract
Background
Anti-tubercular medications can cause hepatic degradation in patients on first-line therapy. However, the hepatoprotective medications used as an encounter therapy to protect the patients. Hepatoprotective drugs like Ursodeoxycholic acid (UDCA) and Liv-52 are proven safe and effective, the high cost of UDCA raises concerns for prescribing. This study aimed to compare UDCA's cost-effectiveness with Liv-52.
Materials & Methods
A randomized open-label controlled trial conducted at Rajendra Memorial Institute of Medical Sciences (RMRIMS), Patna. The study participants were recruited based on the inclusion criteria and were randomly divided into two groups, i.e., Group A (n = 28) and Group B (n = 27), where Liv-52 and UDCA drugs were prescribed. To compare the cost-effectiveness of this regimens LFT and cost related data were gathered from each patient, Incremental Cost Effective Ratio (ICER) was used to combine the results. SPSS v28 was used for final data analysis.
Results
A total of 80 patients were recruited initially, fifty seven patient data were included in the final analysis. The outcome measures included total bilirubin, alanine aminotransferase, aspartate aminotransferase, and alkaline Phosphatase. All the LFT clinical parameters are clinically significant but not statistically. But the Incremental cost-effectiveness ratio of Liv-52 and UDCA related to the change in Liver function test profile is statistically significant (p < 0.05) where UDCA is more costly than Liv-52.
Conclusion
The results demonstrated that the patients treated with Liv-52 and UDCA for 6 months had significantly better hepatoprotective activity and normal liver enzyme levels. We conclude that Liv-52 and UDCA possess hepatoprotective effects in tuberculosis patients, and when it related to cost effectiveness, Liv-52 is cheaper for the patients.
WITHDRAWN: A Microphase-Separated Design Toward an All-Round Ionic Hydrogel with Discriminable and Anti-Disturbance Multisensory Functions
Authors: Liang Jiajie , Liu Xue , JI Xinyi , Zhu Rongjie , Gu Jianfeng 
Published: July 2023

Abstract
Stretchable ionic hydrogels with superior all-round properties that can detect multimodal sensations with high discriminability to decouple multiple stimuli and high robustness against external disturbances are highly required for artificial electronic skin applications. However, some of the critical material parameters exhibit intrinsic tradeoffs with each other for most ionic hydrogels. Here, we demonstrate a microphase-separated hydrogel design by combining three strategies: (1) the use of a low crosslinker/monomer ratio to obtain highly entangled polymer chains as the first network; (2) the introduction of zwitterions into the first network; (3) the synthesis of a ultrasoft polyelectrolyte as the second network. This approach creates an all-round elastic ionic hydrogel with a skin-like Young’s modulus (< 60 kPa), large stretchability (> 900%), high resilience (> 95%), low hysteresis (< 5%), unique strain-stiffening behavior, excellent fatigue tolerance, high ionic conductivity (> 2.0 S/m), and anti-freezing capability, which were not achieved with previous ionic hydrogels. These comprehensive properties allow the ionic hydrogel to operate as a stretchable multimodal sensor that can detect and decouple multiple stimuli (temperature, pressure, and proximity) with both high discriminability and sensitivity. It also shows strong sensing robustness against large strains and subzero temperature perturbations. The ionic hydrogel sensor exhibits great potential for intelligent electronic skin applications such as reliable health monitoring and accurate object identification.
Perception of Female Staff Towards the Involvement of Obstetrics and Gynecology Patients in Medical Students’ Training
Authors: Aljunaid Linda 
Published: July 2023

Abstract
Objectives: To determine the perception of female healthcare providers towards the involvement of medical students in obstetrics and gynecology training.
Methods: This was an anonymous, self-administered questionnaire to female healthcare providers regarding medical students’ training in the Obstetrics and Gynecology department in 2013 (n=114) and repeated in 2021 (n=105). Descriptive analyses were done. Comparison of the variables between 2013 and 2021 was performed using a paired t-test. The p-value was considered significant if p<0.05.
Results: A total of 219 healthcare providers participated in the study. Their perception regarding femalepatients’ acceptance of medical students was low. This increased from 81.6% (n=114) in 2013 to 93.3% (n=105) in 2021 towards male students (p=0.01). Similar findings were perceived towards female medical students. Agreement on the use of simulation-based training for male medical students increased from 53.5% (n=114) to 70.5% (n=105) (p=0.01). The percentage of healthcare providers who disagreed with having a vaginal examination by a male obstetrician increased from 39.5% (n=114) to 54.3% (n=105) (p=0.02).
Conclusions:
The study raises concerns regarding the clinical exposure of medical students during OBGYN training. Male medical students remain at a disadvantage during their training. Greater attention might be needed towards educating healthcare providers to encourage patients’ engagement during clinical training sessions. Simulation-based training should be incorporated within medical curriculums.
“I’m getting it!”: How Parents Describe Change Following Attendance at Mindfulness- Enhanced Behavioral Parent Training
Authors: Donovan Mark O. , Barkus Emma , Pickard Judy A. , Risi Alixandra , Herbert Jane S. 
Published: July 2023

AbstractMany parents feel overwhelmed and seek professional assistance in response to their child’s behaviors. Mindfulness-enhanced parenting programs offer an increasingly popular alternative to the traditional gold standard behavioral parent training (BPT). This study explored parents’ descriptions of change following attendance at a mindfulness-enhanced behavioral parent training group program (MeBPT). Our aim was to examine how mindfulness and behavioral components are featured in parents’ change narratives. Semistructured interviews were conducted with parents (N = 9) of 3–12-year-old children, who attended the program 6 months earlier. Transcripts were analyzed using reflexive thematic analysis. Identified themes were triangulated with qualitative comments fromN = 266 postgroup parent evaluations and relevant theory. Four themes characterized parents’ change narratives: noticing the struggle, being a mindful parent, trying to implement behavioral strategies, and the importance of the relationship. Parents integrated both mindfulness and behavioral principles in their change narratives, varied in which components were most highly valued, and reported mixed success in applying behavioral parenting strategies. Themes supported the construct validity of mindful parenting mechanisms and measures. Integrating mindfulness components within BPT programs appears to be valued by parents and may represent the next evolution in parenting interventions.
WITHDRAWN: Novel splicing variants in ARR3 gene cause the female- limited early-onset high myopia
Authors: Niu Jianing , Zhu Weili , Jin Xiaoying , Teng Xiaoming , Zhang Junyu 
Published: July 2023

Abstract
X-linked heterozygous variants in ARR3 have been associated with the development of female-limited early-onset high myopia (eoHM). However, the clinical validity of this gene-disease association has yet to be systematically assessed. In this study, we identified two novel ARR3 splicing variants in two Chinese families affected by eoHM. Using minigene approach and RNA analyses, we found that both variants result in aberrant mRNA fragments, retaining a segment of the adjacent intron. The aberrant mRNA produced by c.39 + 1G > A variant and c.100 + 4A > G variant were both predicted to introduce a premature termination codon, resulting in a truncated protein. Additionally, we curated the clinical validity of ARR3 and eoHM as as "Definitive" using the ClinGen Gene Curation Framework. Thus, our study not only demonstrated that two novel ARR3 splicing variants are associated with eoHM but also confirmed the clinical validity of ARR3 and eoHM.
Sensitive electrochemical detection of L-Cysteine in milk sample based on Cobalt-CNT composite modified screen-printed gold electrode
Authors: Xiang Miao , Li Yiyi , Liu Jin , Xiao Ling , Pei Jiameng , Yang Biru , Liao Tangbin , Tang Li-Na 
Published: July 2023

Abstract
The detection and quantification of cysteine in various food industries is crucial. An electrochemical sensor was developed using a screen-printed gold electrode (GE) that was modified with a nanocomposite of carbon nanotubes (CNTs) and cobalt phthalocyanine (CoPC) (CoPC/CNTs) for sensitive detection of L-Cysteine in milk. The CoPC/CNTs nanocomposite was synthesized using ultrasound, and then deposited onto the polished surface of the GE using an electrochemical method. The designed sensor was highly sensitive and specific, owing to the favorable catalytic properties of CoPC and the excellent electron transport capacity of CNTs. The results demonstrated that the CoPC/CNTs sensor was capable of real-time detection of L-Cysteine from 1 µM to 1 mM with a low detection limit of 0.52 µM and excellent selectivity and stability. Moreover, the developed electrodes were used to detect cysteine in milk samples, achieving a recovery rate of 95%-98%. This work provides reliable technical support for the field of food analysis and detection.
Analog circuit fault diagnosis based on feature attention
Authors: Du Xianjun , Cao Lei 
Published: July 2023

Abstract
Aiming at the troubles of effective extraction of fault features, large model calculation, low-accuracy diagnosis and poor stability, this paper proposes an analog circuit fault diagnosis method that is based on an improved CNN-Transformer model. To achieve comprehensive and effective extraction of fault features, one-dimensional convolution is implemented to obtain the local features in the data, and multi-head attention is employed to catch the global features. A Sallen-Key band-pass filter, a fourth-order state-variable filter and a Butterworth low-pass filter circuits are applied as the experimental subjects for comparison to verify the effectiveness and advancement of the proposed CNN-Transformer method. The results indicate that of the suggested CNN-Transformer model is able to effectively enhance diagnostic accuracy and stability, achieve accurate diagnosis and localization of circuit fault components, which could be a helpful reference for engineering practice in analog circuit fault diagnosis.
Identification and designed QTL breeding of reliable QTLs for milling quality and grain shape in the reciprocal introgression lines in rice
Authors: Emelin Mwenda , Qiu Xianjin , Fan Fangjun , Alami Md. , Faruquee Muhiuddin , Hu Hui , Xu Junying , Yang Jie , Xu Haiming , Ali Jauhar , Liu Bailong , Shi Yumin , Li Zhikang , Zhang Luyan , Zheng Tianqing , Xu Jianlong 
Published: July 2023

Abstract
Milling quality (MQ) and grain shape (GS) of rice (Oryza sativa L.) are correlated traits and both determining farmers’ final profit. More than one population under multiple environments may provide valuable information for breeding selection on this MQ-GS correlations. However, suitable analytical methods for reciprocal introgression lines with linkage map for this kind of correlation remains unclear. In this study, our objectives were (1) to provide a set of reciprocal introgression lines (composed by two BC2RIL populations) suitable for mapping by linkage mapping using markers/bins with physical positions; (2) to test mapping effect by MQ-GS correlation dissection by different mapping methods; (3) to perform genetic and breeding simulation to pyramid favorite alleles of QTLs for representative MQ-GS traits. Finally, with four analysis methods and data collected under five environments, we identified about 28.4 loci in average for MQ-GS traits. It’s notable that 52.3% of these loci were commonly detected by different methods and eight loci were novel. There were also nine regions harboring loci for different MQ-GS traits which may be underlying the MQ-GS correlations. Background independent (BI) loci were also found for each MQ and GS trait. All these information may provide useful data for rice molecular breeding.