bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transdiagnostic MRI Markers of Psychopathology following Traumatic Brain Injury: A Systematic Review and Meta-Analysis Protocol
Authors: Samiotis Alexia , Hicks Amelia J , Ponsford Jennie , Spitz Gershon 
Published: January 2023

AbstractIntroductionPsychopathology following traumatic brain injury (TBI) is a common and debilitating consequence that is often associated with reduced functional and psychosocial outcomes. There is a lack of evidence regarding the neural underpinnings of psychopathology following TBI, and whether there may be transdiagnostic neural markers that are shared across traditional psychiatric diagnoses. The aim of this systematic review and meta-analysis is to examine the association of MRI-derived markers of brain structure and function with both transdiagnostic and specific psychopathology following moderate-severe TBI.Methods and analysisA systematic literature search of Embase (1974–2022), Ovid MEDLINE (1946–2022) and PsycINFO (1806–2022) will be conducted. Publications in English that investigate MRI correlates of psychopathology characterised by formal diagnoses or symptoms of psychopathology in closed moderate-severe TBI populations over 16 years of age will be included. Publications will be excluded that: a) evaluate non-MRI neuroimaging techniques (CT, PET, MEG, EEG); b) comprise primarily a paediatric cohort; c) comprise primarily penetrating TBI. Eligible studies will be assessed against a modified Joanna Briggs Institute Critical Appraisal Instrument and data will be extracted by two independent reviewers. A descriptive analysis of MRI findings will be provided based on qualitative synthesis of data extracted. Quantitative analyses will include a meta-analysis and a network meta-analysis where there is sufficient data available.Ethics and disseminationEthics approval is not required for the present study as there will be no original data collected. We intend to disseminate the results through publication to a high-quality peer-reviewed journal and conference presentations on completion.PROSPERO registration numberCRD42022358358Article SummaryStrengths and limitations of this study:This is a comprehensive review of MRI markers of psychopathology among adults with moderate – severe traumatic brain injuries.We will investigate neural correlates across the spectrum of psychopathology rather than focusing on specific diagnoses, allowing for transdiagnostic investigations of brain structure and function alterations after TBI with comorbid psychopathology.We will be restricting eligible studies to English language.We will capture pre-injury psychopathology where data are available and analyse the associations with post-injury psychopathology and neural correlates.
Light and temperature regulate m6A-RNA modification to regulate growth in plants
Authors: Artz Oliver , Ackermann Amanda , Taylor Laura , Koo Peter K. , Pedmale Ullas V. 
Published: January 2023

ABSTRACTN6-methyladenosine is a highly dynamic, abundant mRNA modification which is an excellent potential mechanism for fine tuning gene expression. Plants adapt to their surrounding light and temperature environment using complex gene regulatory networks. The role of m6A in controlling gene expression in response to variable environmental conditions has so far been unexplored. Here, we map the transcriptome-wide m6A landscape under various light and temperature environments. Identified m6A-modifications show a highly specific spatial distribution along transcripts with enrichment occurring in 5’UTR regions and around transcriptional end sites. We show that the position of m6A modifications on transcripts might influence cellular transcript localization and the presence of m6A-modifications is associated with alternative polyadenylation, a process which results in multiple RNA isoforms with varying 3’UTR lengths. RNA with m6A-modifications exhibit a higher preference for shorter 3’UTRs. These shorter 3’UTR regions might directly influence transcript abundance and localization by including or excluding cis-regulatory elements. We propose that environmental stimuli might change the m6A landscape of plants as one possible way of fine tuning gene regulation through alternative polyadenylation and transcript localization.
Reduced glycolysis links resting zone chondrocyte proliferation in the growth plate
Authors: Kobayashi Tatsuya , Young Cameron , Zhou Wen , Rhee Eugene P. 
Published: January 2023

AbstractA gain-of-function mutation of the chondrocyte-specific microRNA, miR-140-5p, encoded by the MIR140 gene, causes spondyloepiphyseal dysplasia, Nishimura type (SEDN, also known as SED, MIR140 type; MIM, 611894). We reported that a mouse model for SEDN showed a unique growth plate phenotype that is characterized by an expansion of the resting zone of the growth plate and an increase in resting chondrocytes, of which the mechanism of regulation is poorly understood. We found that the miR-140 mutant chondrocytes showed a significant reduction of Hif1a, the master transcription factor that regulates energy metabolism in response to hypoxia. Based on this finding, we hypothesized that energy metabolism plays a regulatory role in resting chondrocyte proliferation and growth plate development. In this study, we show that suppression of glycolysis via LDH ablation causes an expansion of the resting zone and skeletal developmental defects. We have also found that reduced glycolysis results in reduced histone acetylation in the miR-140 mutant as well as LDH-deficient chondrocytes likely due to the reduction in acetyl-CoA generated from mitochondria-derived citrate. Reduction in acetyl-CoA conversion from citrate by deleting Acly caused an expansion of the resting zone and a similar gross phenotype to LDH-deficient bones without inducing energy deficiency, suggesting that the reduced acetyl-CoA, but not the ATP synthesis deficit, is responsible for the increase in resting zone chondrocytes. Comparison of the transcriptome between LDH-deficient and Acly-deficient chondrocytes also showed overlapping changes including upregulation in Fgfr3. We also confirmed that overexpression of an activation mutation of Ffgr3 causes an expansion of resting zone chondrocytes. These data demonstrate the association between reduced glycolysis and an expansion of the resting zone and suggest that it is caused by acetyl-CoA deficiency, but not energy deficiency, possibly through epigenetic upregulation of FGFR3 signaling.
One economy, but different growth regimes: why Germany’s rural east is still lagging
Authors: Margarian Anne , Hundt Christian 
Published: January 2023

Purpose
This study aims to elucidate the quantitative and qualitative differences in employment development between German districts. Building on ideas from competitive development and resource-based theory, the paper particularly seeks to explain enduring East-West differences between rural regions by two different forms of competitive advantage: cost leadership and quality differentiation.

Design/methodology/approach
This study follows a two-step empirical approach: First, an extended shift-share regression is conducted to analyze employment development in Western and Eastern German districts between 2007 and 2016. Second, the competitive share effect and other individual terms of the shift-share model are further examined in additional regressions using regional economic characteristics as exogenous variables.

Findings
The findings suggest that the above-average employment growth of the rural districts in the West is owed to the successful exploitation of experience in manufacturing that has been gathered by firms in the past 100 years or so. While their strategy is largely based on advanced and specialized resources and an innovation-driven differentiation strategy, the relatively weak employment development of Eastern rural districts might be explained by a lack of comparable long-term experiences and the related need to focus on the exploitation of basic and general resources and, accordingly, on the efficiency-based strategy of cost leadership.

Originality/value
This study offers an in-depth empirical analysis of how the competitive share effect, i.e. region-specific resources beyond industry structure, contributes to regional employment development. The analysis reveals that quantitative differences in rural employment development are closely related to qualitatively different levels of input factors and different regimes of competitiveness.
Households’ willingness to adopt solar energy for business use in Uganda
Authors: Nabaweesi Jennifer , Kabuye Frank , Adaramola Muyiwa Samuel 
Published: January 2023

Purpose
The adoption of solar energy by households is an important avenue of protecting the environment and enabling energy access in rural areas, especially in developing countries like Uganda, where energy access is low. Therefore, this study aims to investigate the factors that influence the households’ willingness to adopt solar photovoltaic (PV) energy and how soon the households are willing to adopt solar PV energy for business use in Uganda.

Design/methodology/approach
Heckman’s two-step selection model was used to determine the willingness and urgency of adopting solar PV energy for business use in selected districts in Eastern Uganda. The respondents were selected purposively at the household level at a given point in time.

Findings
Results show that sex, household head estimated income, mode of acquisition and repayment terms of solar technology positively influence both willingness and urgency to adopt solar energy for business use in households. However, financial disclosure only influences willingness to adopt solar. Then, age and energy need only significantly influence how soon the household is willing to adopt solar PV energy for business use.

Research limitations/implications
This study’s findings essentially apply to the individual factors that determine the willingness and urgency to adopt solar PV energy for business use by households. Hence, further research is needed to understand the external and industrial factors which could strengthen the predictive potential of the elements in this study.

Practical implications
This study underscores the need for regulatory enforcement on the supply and usage of quality, reliable and affordable solar equipment which are suitable for business use. Also, the need to promote and finance the usage of solar PV as a green energy source for household businesses has been emphasized.

Originality/value
The study simultaneously examines the willingness and urgency to adopt solar PV energy for household business purposes using Heckman’s two-step selection model. This has hitherto remained unknown empirically.
Use of debriefing following restrictive practices in forensic psychiatric care
Authors: Asikainen Jaana , Vehviläinen-Julkunen Katri , Repo-Tiihonen Eila , Louheranta Olavi 
Published: January 2023

Purpose
Inpatient violence is a substantial problem in psychiatric wards and de-escalation is difficult. When managing instances of violence through verbal techniques fail, mental health-care staff may use restrictive practices. The Six Core Strategies and debriefing exist for managing violence and restrictive practices in different mental health settings. Debriefing is used to get patients’ views on restrictive practices, ensure proper patient care and strengthen the role of patients as experts. This study aims to provide new information on debriefing implementation and how debriefing was used among different patient groups in a forensic hospital.

Design/methodology/approach
Quantitative seclusion time and debriefing reports (n = 524) were examined with Poisson regression analysis. Fisher’s exact test was used to determine the associations between debriefing and seclusion/restraint.

Findings
Debriefing (n = 524) was provided in 93% of violent episodes, which is an excellent result on an international level. There was significant variation in how often debriefing was used (p < 0.001) among different patient groups, i.e. dangerous, difficult-to-treat patients and criminal offenders whose sentences have been waived. Previous debriefing research has rarely specified what types of psychiatric patients have been subjected to seclusion or restraint.

Practical implications
The implementation of debriefing requires multiprofessional work within the organization and wards.

Originality/value
Debriefing seems to stimulate reflection at every level of a health-care organization, which fosters learning and can ultimately change clinical practices. The use of debriefing can strengthen the role of patients as well as professionals.
Halal supply chain: a bibliometric analysis
Authors: Rusydiana Aam Slamet , Irfany Mohammad Iqbal , As-Salafiyah Aisyah , Tieman Marco 
Published: January 2023

Purpose
This paper aims to study research performance in halal supply chains. This study identifies the leading scholars, research themes and leading journals.

Design/methodology/approach
This study adopts the bibliometric method. A total of 228 research publications indexed by Scopus were analysed. The export data are then processed and analysed using the R Biblioshiny application program to find out the bibliometric map of the halal supply chain.

Findings
Research in halal supply chain has experienced fast growth since 2016, dominated by food-centric research by Malaysian universities. Research gaps are topics: halal procurement, halal clusters and halal value chain; industry: non-food; and countries: beyond Malaysia. Future expected halal supply chain trending research areas are: halal blockchains, halal supply chain management, halal performance, halal risk management and sustainability in halal supply chains.

Research limitations/implications
This research paper adopts a bibliometric method based on English publications on the halal supply chain theme from the Scopus database collected on November 1, 2021. Publications in local languages, as well as publications in non-academic journals, are being ignored in this research.

Practical implications
This study shows that halal supply chain management is an emerging requirement, is complex to manage for brand owners and needs new concepts and tools for halal industries to embrace a halal supply chain and value chain approach.

Originality/value
This study provides an objective evaluation of the research progress in halal supply chains; this study highlights the achievements and the research gaps and discusses the contribution to the scientific community.
Truces (re)construction at the boundaries of budgeting routines
Authors: Broman Samantha Luiza de Souza , Rocha-Pinto Sandra Regina da 
Published: January 2023

Purpose
This study aims to contribute to routine dynamics literature and organization process practices. The main objective is to identify different ways organizational members (re)construct truces at the boundaries of budgeting routines where (re)plannings face scarce resources and, consequently, require modifications in routines.

Design/methodology/approach
The research adopted the phenomenographic theoretical-methodological approach to investigate from a process perspective. Twenty-two professionals from 17 companies were interviewed about their experiences with budgeting. Three conceptions and six explanatory dimensions were organized systematically on a conceptual map, which provided insights for three new propositions.

Findings
Three conceptions about truce (re)construction were found: “authority subjection” denotes an obedient behavior toward centralized orders for budget cuttings; “prudent assimilation” explains how some specific routines are preserved from resource reduction; and “participatory interactions” stand for exhaustive and participative efforts for negotiations beyond routine frontiers. Three theoretical propositions are also presented: “awareness of systemic complexity” may strengthen arguments for negotiations; “team’s collective configuration of relationship networks” reinforces collective attributes; and “social-based learning” may be developed through truce (re)construction.

Research limitations/implications
Jorgüen Sandberg, who brought the phenomenographic approach to Organization Studies in 2000, stances that it is not assured that conceptions cover all varied forms of the phenomenon.

Practical implications
Implementing these findings in organizations may improve commitment to ecology of routines and decentralized decisions with a sense of responsibility for financial plans.

Social implications
This study encourages transparency and ideas for cost-efficient resource use.

Originality/value
This study provides advance knowledge about truce in routines while encompassing its ecology.
A compressive review on different surface finishing of cotton fabrics
Authors: Enawgaw Haymanot 
Published: January 2023

Purpose
The purpose of this paper is to give compiled information on previously applied cotton fabric surface modifications. The paper covered most of the modifications done on cotton fabric to improve its properties or to add some functional properties. The paper presented mostly studied research works that brought a significant surface improvement on cotton fabric.

Design/methodology/approach
Different previous works on surface modifications of cotton fabrics such as pilling, wrinkle and microbial resistance, hydrophobicity, cationization, flame retardancy and UV-protection characteristics were studied and their methods of modification including the main findings are well reported in this paper.

Findings
Several modification treatments on surface modification of cotton fabrics indicated an improvement in the desired properties in which the modification is needed. For instance, the pilling tendency, wrinkling, microbial degradation and UV degradation drawbacks of cotton fabric can be overcome through different modification techniques.

Originality/value
To the best of the author’s knowledge, there are no compressive documents that covered all the portions presented in this review. The author tried to cover the surface modifications done to improve the main properties of cotton fabric.
Sericin eco-friendly biomaterial as a spin finish in drawn textured PET yarn production
Authors: Zare Abolfazl 
Published: January 2023

Purpose
This paper aims to extracted sericin from the cocoons of Bombyx mori silkworms, and sericin powder was applied onto drawn textured polyethylene terephthalate (PET) yarns as a spin finish. The reactivity on the surface of PET yarns was analyzed through Fourier transform infrared spectrophotometry–attenuated total reflectance (FTIR-ATR) and dyeing with methylene blue as a reactive dye. Also, investigations were conducted on the effects of sericin, citrc acid (CA) (as a crosslinking agent), and sodium hypophosphite (as a catalyst) concentrations on some properties of false-twist textured PET yarns.

Design/methodology/approach
A false-twist texturing machine (Scragg-Shirley minibulk, England) was used with the draw ratio of 1.05, heating temperature of 120°C, texturing speed of 100 m min−1 and applied twist of 3,000 TPM. The aqueous extraction of sericin was carried out by the boiling of the raw silk in distilled water with L:R: 40:1 for 120 min. The aqueous solution was filtered with a filter paper to remove the impurities and insoluble fibroin. Finally, the sericin solution was freeze-dried to obtain the sericin powder. The sericin solution was applied on the drawn textured PET yarns using the “pad-dry-cure” method.

Findings
Sericin fixation onto the PET yarns was confirmed by FTIR-ATR. The results showed that there were no significant changes in the tensile strength, linear density, crimp contraction and crimp modulus, elongation at break and shrinkage. In contrast, a substantial increase was observed in moisture regain, vertical wicking, dye uptake and ultraviolet protection. There was also a reduction just in the electrical resistivity, in the presence of sericin.

Originality/value
Although sericin has been known to have numerous beneficial properties, its application in textile industry as a spin finish has not been reported yet.
Hair loss after drug reaction with eosinophilia and systemic symptoms (DRESS): A multicentric retrospective case series
Authors: Lee Ji Won , Yu Da‐Ae , Cho Soyun , Youn Sang Woong , Kwon Ohsang 
Published: January 2023

AbstractDrug reaction with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous drug adverse reaction characterized by various cutaneous and systemic manifestations. However, reports on the various patterns of alopecia after DRESS are lacking. Thus, we aimed to describe cases of alopecia after DRESS and review the literature. This multicentric retrospective study reviewed the records of 182 patients diagnosed with DRESS from 2009 to 2021; of these, 10 who had alopecia after DRESS were included. Patients were diagnosed with permanent alopecia (n = 4), telogen effluvium (n = 5), and alopecia areata (n = 1), and were treated with topical minoxidil or alfatradiol (6; 60%), topical corticosteroids (3; 30%), dietary supplements (6; 60%), systemic corticosteroids (1; 10%), and intralesional corticosteroid injection (2; 20%). Although patients with permanent alopecia did not show hair regrowth after 6 months, those with telogen effluvium and alopecia areata experienced marked clinical improvement within 6 months. Various types of alopecia can persist over an extended period, even after the resolution of an acute episode of DRESS.
Trichoblastic carcinosarcoma of the neck: Case report and molecular analysis of a seldom, relapsing entity and a review of the literature
Authors: Weiland Thomas , Sadoghi Birgit , Pondorfer Prisca , Kiss Peter , Brcic Iva , Thurnher Dietmar 
Published: January 2023

AbstractTrichoblastic carcinosarcoma is a seldom biphasic adnexal tumor with malignant epithelial and mesenchymal components. The authors report the first tumor on the neck developed from preexistent trichoblastoma showing aggressive, recurrent behavior. An 82‐year‐old man presented with a solitary 3‐cm exophytic lesion. Histology verified the diagnosis of trichoblastic carcinosarcoma. Four years earlier, a trichoblastic carcinoma arising in a preexisting trichoblastoma was excised at the same location. Despite successful surgical treatments, three local recurrences within 4 years were diagnosed. After the second relapse, the patient agreed on adjuvant radiation. Twelve months later, another relapse was excised in toto. In the last surgical specimen, only the mesenchymal component was found. Copy number variation analysis of the preexisting tumor and two recurrences revealed the same entity and additional chromosomal aberrations in the recurrences. Adnexal carcinosarcomas are seldom, yet presumably underdiagnosed biphasic tumors with aggressive growth potential. They should have adequate preoperative clarification with wide tumor excision, as radiosensitivity seems to be of limited effect.