bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioengineered Living Entities in Art: Aliveness, Duration, and Movement in Bricolage
Authors: O’Reilly Ziggy , Chau Christina , Thompson Nathan , Ben-Ary Guy 
Published: March 2023

Abstract
Bricolage is a kinetic biological artwork first exhibited at the Perth International Arts Festival in 2020. The artists used stem cell technologies to create bioengineered living entities from donated human heart muscle cells. These living entities are suspended in an incubator from the ceiling and are made visible to gallerygoers, who watch the performance of cells generating and moving independently. This paper considers how the assemblage, animation, and performance of cells embedded in Bricolage highlight questions around the conceptualizations and perceptions of life, duration, animation, and aliveness.
Cartography of Touch: Transformation of Touch through Anatomical Projections
Authors: Pokojná Hana 
Published: March 2023

Abstract
Both the conception of how people connect changes with the evolution of technology and the circumstances under which we interact changed drastically with the onset of the global COVID-19 pandemic and have changed again during the decline of the pandemic threat. With the art installation Cartography of Touch, the author uses digital and physical media (3D printing and projection mapping of human physiology) to demonstrate the need for human touch. The installation depicts response to touch as the joining of the technological age and the need for essential human interaction through physical touch, which cannot be replaced, using plastic human hands with artificial responses.
Population size and diurnal activity patterns of Bohor reedbuck (Redunca redunca Pallas, 1767) in the compound of Alage Agricultural College, Central Rift Valley of Ethiopia
Authors: Derebe Yonas , Girma Zerihun , Alemkere Azmeraw 
Published: March 2023

Abstract
Bohor reedbuck is a medium-sized, even-toed ungulate species endemic to Africa. Its population is gradually declining, and an estimation of Meta populations is required to determine its current population status and as an input for conservation action. To this end, this study aimed to investigate this species’ population size and diurnal activity patterns in the compound of Alage Agricultural College, Central rift valley of Ethiopia. A total count was conducted to determine the population size of Bohor reedbuck by dividing the study area into different blocks. Continuous focal animal observations were used to collect data on activity patterns by recording group activities with five minutes intervals. The results revealed that the mean population size of Bohor reedbuck counted during the study period was (SE) with a density of 1.74 per km2. Females formed the dominant group in the population. From the mean total population size of Bohor reedbucks, 47.42% were adults. The mean group size of Bohor reedbuck was (SE). Feeding (, 45.81%) was the dominant mean diurnal activity pattern of Bohor reedbuck, followed by Resting (, 31.91%), whereas grooming (, 3.51%) was the least performed activity. There was a significant difference between the diurnal activities performed by Bohor reedbuck (). The studied compound is an important refuge for this species, and minimum management interference can increase the population size of Bohor reedbuck in the area.
Bulk Microphysical Characteristics of a Heavy-Rain Complex Thunderstorm System in the Taipei Basin
Authors: Jung Chi-June , Jou Ben Jong-Dao 
Published: March 2023

Abstract
Severe rainfall has become increasingly frequent and intense in the Taipei metropolitan area. A complex thunderstorm in the Taipei Basin on 14 June 2015 produced an extreme rain rate (>130 mm h−1), leading to an urban flash flood. This paper presents storms’ microphysical and dynamic features during the organizing and heavy rain stages, mainly based on observed polarimetric variables in a Doppler radar network and ground-based raindrop size distribution. Shallower isolated cells in the early afternoon characterized by big raindrops produced a rain rate > 10 mm h−1, but the rain showers persisted for a short time. The storm’s evolution highlighted the behavior of merged convective cells before the heaviest rainfall (exceeding 60 mm within 20 min). The columnar features of differential reflectivity (ZDR) and specific differential phase (KDP) became more evident in merged cells, which correlated with the broad distribution of upward motion and mixed-phase hydrometeors. The KDP below the environmental 0°C level increased toward the ground associated with the melted graupel and resulted in subsequent intense rain rates, showing the contribution of the ice-phase process. Due to the collision–breakup process, the highest concentrations of almost all drop sizes and smaller mass-weighted mean diameter occurred during the maximum rainfall stage.
Improving National Blend of Models Probabilistic Precipitation Forecasts Using Long Time Series of Reforecasts and Precipitation Reanalyses. Part II: Results
Authors: Stovern Diana R. , Hamill Thomas M. , Smith Lesley L. 
Published: March 2023

Abstract
This second part of the series presents results from verifying a precipitation forecast calibration method discussed in the first part, based on quantile mapping (QM), weighting of sorted members, and dressing of the ensemble. NOAA’s Global Ensemble Forecast System, version 12 (GEFSv12), reforecasts were used in this study. The method was validated with preoperational GEFSv12 forecasts from December 2017 to November 2019. The method is proposed as an enhancement for GEFSv12 precipitation postprocessing in NOAA’s National Blend of Models. The first part described adaptations to the methodology to leverage the ∼20-yr GEFSv12 reforecast data. As shown here in this part, when compared with probabilistic quantitative precipitation forecasts from the raw ensemble, the adapted method produced downscaled, high-resolution forecasts that were significantly more reliable and skillful than raw ensemble-derived probabilities, especially at shorter lead times (i.e., <5 days) and for forecasts of events from light precipitation to >10 mm (6 h)−1. Cool-season events in the western United States were especially improved when the QM algorithm was applied, providing a statistical downscaling with realistic smaller-scale detail related to terrain features. The method provided less value added for forecasts of longer lead times and for the heaviest precipitation.
hMSH2 coordinated with the expression of E2F1 promotes platinum response in epithelial ovarian cancer
Authors: Hu Xiao-qian , Zhang Bao-ying , Hua Tian 
Published: March 2023

Objective To explore underlying mechanisms that regulate hMSH2 expression and drug susceptibility in epithelial ovarian cancer (EOC). Methods Using data from the Cancer Genome Atlas (TCGA) we used bioinformatical analysis to predict transcription factors (TFs) that potentially regulate hMSH2. RT-qPCR, Western blot, and luciferase assays were undertaken using ovarian cancer cell lines to verify the identified TF. Expressions of the TF were modulated using overexpression or knockdown, and the corresponding cellular responses to cisplatin were examined. Results The TF, E2F1, was found to regulate the hMSH2 gene. The expression level of E2F1 correlated with cisplatin susceptibility in vitro. Kaplan-Meier analysis of 77 patients with EOC showed that low E2F1 expression was associated with worse survival. Conclusions To our knowledge, this is the first report of E2F1 regulated MSH2 expression playing a role in drug resistance of platinum-based treatments for patients with EOC. Further work is need to confirm our results.
“I think I could have coped if I was sleeping better”: Sleep across the trajectory of caring for a family member with dementia
Authors: Gibson Rosemary , Helm Amy , Ross Isabelle , Gander Philippa , Breheny Mary 
Published: March 2023

Dementia-related sleep changes can lead to disruptions among families living with dementia which can jeopardise carers’ wellbeing and ability to provide support. This research explores and represents the sleep of family caregivers across the trajectory of caring, before, during, and after the key period of their care recipient moving into residential care. The focus of this paper is viewing dementia caregiving as a trajectory, characterised by care needs which change over time. Semi-structured interviews were conducted with 20 carers whose family member with dementia had transitioned into residential care within the prior 2 years. Themes constructed from these interviews indicated that sleep was linked to earlier life course patterns as well as to significant moments of transition in the caregiving journey. As dementia progressed, carers’ sleep progressively worsened in relation to the less predictable nature of dementia-symptoms, difficulty maintaining routines, and constant responsibilities creating a state of high alert. Carers attempted to facilitate better sleep and wellbeing for their family member, often sacrificing their own self-care. Around the care transition period, some cares reported not realising how sleep deprived they were; for others the busy momentum continued. After the transition, many carers acknowledged that they were exhausted, although many had not realised this while providing home-based care. Post-transition, many carers reported ongoing sleep disruptions associated with poor sleep habits established whilst caring, insomnia or nightmares and grief. Carers were optimistic that their sleep would improve with time and many were enjoying sleeping according to their own preferences. The sleep experience of family carers is unique and includes tensions between their essential need for sleep and the experience of care as self-sacrifice. Findings have implications for timely support and interventions for families living with dementia.
Technical Pitfalls for Fenestrated-Branched Endovascular Aortic Repair Following PETTICOAT
Authors: Baghbani-Oskouei Aidin , Tenorio Emanuel R. , Dias-Neto Marina , Vacirca Andrea , Mirza Aleem K. , Saqib Naveed , Mendes Bernardo C. , Ocasio Laura , Macedo Thanila A. , Oderich Gustavo S. 
Published: March 2023

Purpose: The Provisional Extension to Induce Complete Attachment Technique (PETTICOAT) uses a bare-metal stent to scaffold the true lumen in patients with acute or subacute aortic dissections. While it is designed to facilitate remodeling, some patients with chronic post-dissection thoracoabdominal aortic aneurysms (TAAAs) require repair. This study describes the technical pitfalls of fenestrated-branched endovascular aortic repair (FB-EVAR) in patients who underwent prior PETTICOAT repair. Technique: We report 3 patients with extent II TAAAs who had prior bare-metal dissection stents treated by FB-EVAR. Two patients required maneuvers to reroute the aortic guidewire, which was initially placed in-between stent struts. This was recognized before the deployment of the fenestrated-branched device. A third patient had difficult advancement of the celiac bridging stent due to a conflict of the tip of the stent delivery system into one of the stent struts, requiring to redo catheterization and pre-stenting with a balloon-expandable stent. There were no mortalities and target-related events after a follow-up of 12 to 27 months. Conclusion: FB-EVAR following the PETTICOAT is infrequent, but technical difficulties should be recognized to prevent complications from the inadvertent deployment of the fenestrated-branched stent-graft component in-between stent struts. Clinical Impact The present study highlights a few maneuvers to prevent or overcome possible complications during endovascular repair of chronic post-dissection thoracoabdominal aortic aneurysm following PETTICOAT. The main problem to be recognized is the placement of the aortic wire beyond one of the struts of the existing bare-metal stent. Moreover, encroachment of catheters or the bridging stent delivery system into the stent struts may potentially cause difficulties.
The impact of funding on the quality and interpretation of systematic reviews of mechanical thrombectomy in stroke patients
Authors: Ghozy Sherief , El-Qushayri Amr Ehab , Gbreel Mohamed Ibrahim , Farahat Ramadan Abdelmoez , Azzam Ahmed Y. , Elfil Mohamed , Kobeissi Hassan , Dmytriw Adam , Al-Mufti Fawaz , Kadirvel Ramanathan , Kallmes David F. 
Published: March 2023

Background Funding may impact the quality and findings of systematic reviews (SRs). We aimed to compare the methodological quality of funded and non-funded SRs that investigated the outcomes in ischemic stroke patients undergoing mechanical thrombectomy. Methods We conducted a comprehensive search strategy in different databases, including Ovid Cochrane Central Register of Controlled Trials, Ovid Embase, Ovid Medline (including epub ahead of print, in-process & other non-indexed citations), PubMed, Scopus and Web of Science Core Collection to retrieve all relevant SRs. Random sequence generation matched each funded SR with a non-funded one. A Measurement Tool to Assess Systematic Reviews (AMSTAR)-2 tool was used to assess the bias and quality of the included SRs. We also used uni- and multivariate analysis to perform our analysis, and results were expressed in odds ratio (OR) and 95% confidence interval (CI). Results We retrieved 150 articles, which were randomized and matched into 100 SRs, including 50 funded and 50 non-funded studies. By multivariate analysis, we found that including randomized clinical trials (RCTs) (OR: 5.7; 95% CI: 1.8–17.8; p = 0.003) and reporting conflict of interests (OR: 5.2; 95 CI: 1.1–24; p = 0.036) were the only significant differences between funded and non-funded SRs. No significant differences were found regarding the overall confidence for low-quality (OR: 0.54; 95% CI: 0.09–3.2; p = 0.49) and moderate/high-quality SRs (OR: 0.17; 95% CI: 0.02–1.87; p = 0.14). Conclusion Funded studies tend to include RCTs more often and report conflict of interests with no significant impact on overall confidence.
Electroencephalographic patterns in a mechanically ventilated cat with permethrin intoxication
Authors: Okonji Samuel , Bulgarelli Cecilia , Troìa Roberta , Pontiero Alessandra , Foglia Armando , Giunti Massimo , Gandini Gualtiero 
Published: March 2023

Case summary A 1-year-old male castrated domestic shorthair cat was presented in a condition of status epilepticus following incidental permethrin spot-on administration by its owner. General anaesthesia and mechanical positive pressure control ventilation were necessary to control the epileptic seizures and a progressive condition of hypoventilation. The cat was managed with an intravenous constant rate infusion of midazolam, propofol and ketamine associated with a low-dose intravenous lipid emulsion. A condition of non-convulsive status epilepticus was detected by serial continuous electroencephalogram (cEEG) monitoring. Initial cEEG showed paroxysmal epileptiform discharges; thus, antiseizure treatment with phenobarbital was added and a bolus of hypertonic saline solution was administered to treat suspected intracranial hypertension. A second cEEG performed 24 h later showed the presence of rare spikes and a burst-suppression pattern, so the decision was made to discontinue propofol. A third cEEG, 72 h post-hospitalisation, showed a normal encephalographic pattern; therefore, anaesthetic drugs were progressively tapered, and the patient was extubated. Five days after admission the cat was discharged on phenobarbital treatment, which was gradually tapered during the following months. Relevance and novel information This is the first reported case to describe cEEG monitoring during hospitalisation for feline permethrin intoxication. cEEG should be encouraged in cats with altered mental status that have previously suffered cluster seizures or status epilepticus, which could guide clinicians in the choice of antiseizure drugs.
Effects of volatile sesquiterpenes from Japanese cedarwood on visual processing in the human brain: an event-related potential study
Authors: Nakashima Taisuke , Sun Minkai , Honden Akiyoshi , Yoshimura Yuri , Nakagawa Toshinori , Ishikawa Hiroya , Nagano Jun , Yamada Yuki , Okamoto Tsuyoshi , Watanabe Yuichiro , Yasunari Shinji , Ohnuki Koichiro , Fujimoto Noboru , Shimizu Kuniyoshi 
Published: March 2023

AbstractOdor environments in living spaces can influence human physiological and psychological states. To elucidate the effect of volatile organic compounds (VOCs) of wood in living spaces on the modulations of cognitive processing, we built two experimental huts to simulate wooden construction living spaces. One hut was made of cedarwood (Cryptomeria japonica), and the other was made of resin. We used cedarwood and resin, because they are often used as construction materials in Japan. In both huts, we measured the participants’ first positivity in the early visual cortex (P1), the third positivity elicited by voluntary attention (P3b), and the automatic occipital negativity to infrequent visual stimuli in event-related potentials (ERPs), while they performed a visual discrimination task. The VOCs in both huts were measured by gas chromatography–mass spectrometry. The concentration of volatile sesquiterpenes was significantly increased in the cedarwood hut. Neither P1 nor P3b was affected by the cedarwood hut. Compared to the resin hut, we observed significantly larger occipital negativities to the infrequent stimuli in the cedarwood hut in the time windows of 280–300 ms at the mid-occipital region. These findings suggest that the increased concentration of volatile sesquiterpenes emitted from cedarwood facilitates the human brain’s response to changes in visual stimuli.
Differential responses of contrasting low phosphorus tolerant cotton genotypes under low phosphorus and drought stress
Authors: Iqbal Asif , Huiping Gui , Qiang Dong , Xiangru Wang , Hengheng Zhang , Xiling Zhang , Meizhen Song 
Published: March 2023

Abstract
Background
Drought is one of the main reasons for low phosphorus (P) solubility and availability.

Aims
The use of low P tolerant cotton genotypes might be a possible option to grow in drought conditions.

Methods
This study investigates the tolerance to drought stress in contrasting low P-tolerant cotton genotypes (Jimian169; strong tolerant to low P and DES926; weak tolerant to low P). In hydroponic culture, the drought was artificially induced with 10% PEG in both cotton genotypes followed by low (0.01 mM KH2PO4) and normal (1 mM KH2PO4) P application.

Results
The results showed that under low P, PEG-induced drought greatly inhibited growth, dry matter production, photosynthesis, P use efficiency, and led to oxidative stress from excessive malondialdehyde (MDA) and higher accumulation of reactive oxygen species (ROS), and these effects were more in DES926 than Jimian169. Moreover, Jimian169 alleviated oxidative damage by improving the antioxidant system, photosynthetic activities, and an increase in the levels of osmoprotectants like free amino acids, total soluble proteins, total soluble sugars, and proline.

Conclusions
The present study suggests that the low P-tolerant cotton genotype can tolerate drought conditions through high photosynthesis, antioxidant capacity, and osmotic adjustment.
The transversus abdominis plane block in conjunction with intrathecal morphine use after cesarean section in women with severe pre-eclampsia: a randomized controlled trial
Authors: Yan Zhi-rong , Chen Li-juan , Zhang Su-jing , Zhang Long-xin , Lu Huan , Zhang Li , Liu Ming , Zhou Min , Lin Li-hua 
Published: March 2023

Abstract
Background
The transversus abdominis plane (TAP) block in conjunction with intrathecal morphine has been demonstrated to provide more superior postcesarean analgesia to intrathecal morphine alone. However, the analgesia efficacy of their conjunction has not been demonstrated in patients with severe pre-eclampsia. The study aimed to compare the postcesarean analgesia of TAP block in conjunction with intrathecal morphine versus intrathecal morphine alone in women with severe pre-eclampsia.

Methods
Pregnant women with severe pre-eclampsia undergoing planned cesarean section were randomly allocated into 2 groups to receive TAP block with 20 ml of 0.35% Ropivacaine (TAP group) or with the same volume of 0.9% saline (Sham group) after undergoing elective cesarean section under spinal anaesthesia with 15 mg of 0.5% Ropivacaine plus 0.1 mg of morphine. The outcomes for this analysis include the visual analog scale (VAS) pain score at rest and with movement at 4,8,12,24 h after TAP block was performed, times of use of intravenous patient-controlled analgesia (PCA) within 12 h after anesthesia, the occurrence of maternal side effects, maternal satisfaction, and Apgar score at 1 and 5 min of newborns.

Results
119 subjects receive TAP block with 0.35% Ropivacaine (n = 59)or 0.9% saline (n = 60). At 4,8, 12 h after TAP block, the TAP group reported lower VAS score at rest [at 4 h: 1(0,1) vs. 1(1,2), P < 0.001; at 8 h:1(1,1) vs. 1(1.5,2),P < 0.001; at 12 h:1(1,2) vs. 2(1,2),P = 0.001] and higher satisfaction [53(89.9%) vs.45(75.0%), P < 0.05]. There were no differences between groups in VAS score at 24 h at rest and at all time points above with movement, times of use of PCA within 12 h after anesthesia, maternal side-effect, and Apgar score at 1 and 5 min of newborns.

Conclusions
In conclusion, The TAP block performed in conjunction with intrathecal morphine may not reduce opioid consumption, but it could reduce VAS scores at rest in the first 12 h after cesarean section in women with severe pre-eclampsia, and improve maternal satisfaction, which is worthy of clinical promotion.

Trial registration
Registered at Chinese Clinical Trial Registry(http://www.chictr.org.cn) on 13/12/2021: ChiCTR2100054293.
Analysis of carotid vulnerable plaque MRI high-risk features and clinical risk factors associated with concomitant acute cerebral infarction
Authors: Tang Yongxiang , Zhang Jinping , Liu Weizhou , Jin Wei , Li Shijian , Qian Zhen , Kong Xiaoquan , Zhang Ran , HU Juanjuan , LI Baolin , Yuan Weiming , Zhang Yifan 
Published: March 2023

Abstract
Background
This study aimed to investigate the correlation between the high-risk characteristics of high-resolution MRI carotid vulnerable plaques and the clinical risk factors and concomitant acute cerebral infarction (ACI).

Methods
Forty-five patients diagnosed with a single vulnerable carotid plaque by MRI were divided into two groups based on whether they had ipsilateral ACI. The clinical risk factors and the observation values or frequency of occurrence of high-risk MRI phenotypes of plaque volume, LRNC, IPH and ulcer were statistically compared between the two groups.

Results
A total of 45 vulnerable carotid artery plaques were found in 45 patients, 23 patients with ACI and 22 patients without ACI. There were no significant differences in age, sex, smoking, serum TC, TG and LDL between the two groups (all P > 0.05), but the ACI group had significantly more patients with hypertension (P < 0.05) and the without ACI group coronary heart disease (P < 0.05). The volume of vulnerable carotid plaque in the group with ACI (1004.19 ± 663.57 mm3) was significantly larger than that in the group without ACI (487.21 ± 238.64 mm3) (P < 0.05). The phenotype of vulnerable carotid artery plaque was 13 cases of LRNC, 8 cases of LRNC + IPH, 5 cases of LRNC + Ulcer, and 19 cases of LRNC + IPH + Ulcer. There was no significant difference in this distribution between the two groups (all P > 0.05) with the exception of LRNC + IPH + Ulcer. The 14 cases of LRNC + IPH + LRNC + IPH + Ulcer (60.87%) in the group with ACI and was significantly greater than the 5 (22.73%) in patients without ACI (P < 0.05).

Conclusion
It is preliminarily thought that hypertension is the main clinical risk factor for vulnerable carotid plaques with ACI and the combination of plaque volume with vulnerable carotid plaque and LRNC + IPH + Ulcer is a high-risk factor for complicated ACI. It has high clinical therapeutic value due to the accurate diagnosis of responsible vessels and plaques with high-resolution MRI.