bluuebunny/crossref_metadata_2025_split huggingface dataset:
Actual Conditions and Related Factors of Best Practice/Policy Transfer by Public Health Nurses in Japan: Cross-sectional Nationwide Survey
Authors: Fujioka Mana , Okamoto Reiko , Miyamoto Keiko , Koide Keiko , Kageyama Masako , Saeki Kazuko , Hirokane Kazue , Nagano Fusami , Takemura Shinji 
Published: June 2023

Abstract
Background:
The workload of public health nurses (PHNs) working for local governments has been increasing as health issues become more diverse and complicated. Amidst the ongoing administrative and fiscal reforms, however, making it imperative to find out how to implement projects effectively and efficiently. The objective of this research was to elucidate the actual conditions of best practice/policy transfer (BPT) and analyze related factors.
Methods:
An anonymous postal and self-administered questionnaire survey was conducted among PHNs working at 334 sites, including the local government offices and health centers across Japan, and analysed through statistical analysis.
Results:
One hundred eighty-five of the 334 institutions (55.4%) agreed to participate, and of the 966 questionnaire forms distributed, 709 forms (73.4%) were collected, of which 702 responses (72.7%) were valid. Although less than half (43.2%) have experience in BPT in project development, more than 80% are willing to act going forward. Significant factors for both the group with experience in BPT and the group with willingness to act include an organizational culture that promotes transfer, as well as multiple elements of the workplace environment and facilitating factors related to knowledge and learning. The experienced group recognised the needs for criteria to evaluate the adaptability of best practice/policy, while the willing group, to evaluate the quality of practice/policy.
Conclusions:
Through a nationwide survey, this research elucidated for the first time the actual conditions of BPT by PHNs in Japan and related factors. The results indicated the importance of developing a system to promote BPT at the workplace level, also highlighted the importance for practitioners and experts, including researchers, to work together to develop practical guidelines. Urgent actions are needed to develop a system to promote BPT from diverse perspectives, building on the findings of this research.
Privacy Awareness and Online Behavior of Indian Users: An Analytical Study
Authors: Ingole Chetan Umesh , Bandela Manav , Tanna Dev , Solanki Saurav Kumar , Dhotre Prashant , Patil Rajkumar 
Published: June 2023

Abstract
The rise of mobile and wireless technology has fundamentally changed how people interact, work together, and compute, giving them quick access to a variety of services that have had a significant impact on their lifestyles. Technology is developing quickly, but this has also raised questions about user privacy, which is important for protecting personal information (PIP). In order to assess the attitudes and understanding of user privacy among 221 Indian internet users, a survey was undertaken. The results are presented in this paper. The results show that users usually have a poor opinion of PIP and have different opinions on issues related to privacy than other people. The paper emphasises the need for a PIP protection system that is user-centric and gives users control over their personal data rather than only depending on service providers. A privacy awareness tool's implementation is also identified as essential for building trust between customers and service providers. The study also examines the motivating factors for these beliefs and investigates potential mitigating strategies for the creation of a strong privacy protection system.
Investigation of the Role of Molecules in DNA Repair Process in Coronary Artery Patients
Authors: Malikova Narmina , Karadağ Bilgehan , Durmaz Eser , Ikitimur Baris , Cimci Murat , Guven Mehmet 
Published: June 2023

Abstract
Background The role of DNA damage in the progression of coronary artery disease (CAD) is widely recognized. Among the factors that determine the extent of DNA damage, genetic factors may be one of the determining factors in the pathogenesis of CAD.
Methods & Results In our research, we investigated the expression levels of BRCA1 and PARP1, which are involved in the DNA repair process, as well as the regulators of gene expression for these molecules, namely miR-21-5p, miR-193b-3p, and miR-484, in lymphocyte samples collected from 55 patients with CAD and 55 healthy controls. The fold changes of BRCA1, PARP1, miR-21-5p, miR-193b-3p and miR-484 expression levels in the patient group, as determined by the 2−ΔΔCT calculation, were found to be 0.353, 0.332, 0.734, 0.876, and 1.231, respectively. In the patient group, a statistically significant negative correlation was observed only between PARP1 and miR-21 (r=-0.66, p=0.0001).
ConclusionsThe expression levels in molecules related to the DNA repair systems of CAD patients are clearly related to the pathogenesis of the disease, and considering this situation, measures to be taken would be beneficial.
Flexible Silica/MXene/Natural Rubber film strain sensors with island chain structure for Healthcare Monitoring
Authors: Xue Rong , Wang Chouxuan , Zhao zhongguo , Chen YanHui , Yang Jie , Feng Changping 
Published: June 2023

Abstract
The demand for flexible strain sensors with high sensitivity and durability has increased significantly. However, traditional sensors are limited in terms of their detection ranges and fabrications. In this work, a space stacking method was proposed to fabricate natural rubber (NR)/MXene (Ti3C2Tx)/silica (SiO2) films that possess exceptional electrical conductivity, sensitivity and reliability. The introduction of SiO2 into the NR/MXene composite enabled the construction of an "island-chain structure", which promoted the formation of conductive pathways and significantly improved the conductivity of the composite. Specifically, the electrical conductivity of the NR/MXene/10wt%SiO2 composite was enhanced by about 200 times compared to that of the NR/MXene composite alone (from 0.07 to 13.4 S/m). Additionally, the "island-chain structure" further enhanced the sensing properties of the NR/MXene/10wt%SiO2 composite, as evidenced by its excellent sensitivity (GF = 189.2), rapid response time (102 ms), and good repeatability over 10000 cycles. The fabricated device demonstrates an outstanding mechanical sensing performance and can accurately detect human physiological signals. Specifically, the device serves as a strain detector, recognizing different strain signals by monitoring the movement of fingers, arms, and thighs. This study provides critical insights into composite manufacturing with exceptional conductivity, flexibility, and stability, essential for creating high-performance flexible sensors.
Prevalence and first molecular-phenotypic description of Sarcocystis species in the feces of Egyptian domestic dogs (Canis familiaris)
Authors: Elshahawy Ismail S. , Fawaz Marwa , Gomaa Aya , Mohammed Eman 
Published: June 2023

Abstract

Background
Sarcocystis species are obligatorily heteroxenous protozoan parasites with predator-prey cycle. Global and national Knowledge about the epidemiology and the distribution pattern of different Sarcocystis species in dog feces are very scarce. Therefore, the current investigation was executed to declare the occurrence of Sarcocystis in the fecal specimens of the most common canids in Egypt, the domestic dogs and to recognize the species using parasitological and phenotypic approaches.
Methods
A total of 100 dog fecal samples were gathered and screened using sugar flotation for the presence of Sarcocystis oocysts/sporocysts. Additionally, thirty samples (30) were used for genomic DNA extraction. The 18S rRNA gene fragment was the target of primers for a PCR, followed by purification and sequencing of the amplicons.
Results
Currently, the results obtained appraised that 4% of fecal samples were positive for Sarcocystis spp. Under LM, the sporocysts of the canine S. tenella isolate measured 13.2–16.0 × 9.4–11 µm. Additionally, Sarcocystis spp. were verified in sixteen dogs (53.3%) using PCR and subsequent sequencing protocols. Statistically, insignificant difference in frequency of sarcocystosis relative to age and gender was noticed. Based on 18S rRNA gene, sequencing analysis of amplicons from sporocysts DNA revealed 99.82% nucleotide homology with already reported sequences of S. tenella from sheep in Iraq and Iran.
Conclusions
This is the first molecular evidence in support of the final host role of domestic dogs in the life cycle of S. tenella in Egypt, which provides a precious diagnostic tool for further epidemiological studies and for the assessment of the effectiveness of control measures for this disease.
Annona muricata L. leaves extract loaded on chitosan nanoparticles combined with methotrexate induce Cytotoxicity in A549 cancer cell line
Authors: Muhammad Nada A.E. , Elbeltagy Rasha S. , Diab Marwa S.M. , Gardouh Ahmed R. , El-Habit Ola H. 
Published: June 2023

Abstract
Annona muricata Linn (AM) and methotrexate (MTX)-loaded chitosan (Ch) as a natural cationic, bio-degradable and biocompatible polymer were investigated for their genotoxic and cytotoxic effects in their normal and nano form. The AM-ChNP and MTX-ChNP were analyzed and characterized according to fourier transform infrared spectroscopy (FTIR), particle size, Zeta potential, transmission electron microscope (TEM) and encapsulation efficiency. The chitosan concentration (3:1) was found to be an important parameter for optimizing the dispersion of AM-ChNPs and of MTX-ChNPs nanocomposites over long time. The efficiency was found to be 87.3% and size of 100–200 nm. The stabilty of the nanocomposites offers a good sign in cancer cell line treatment. Seven groups were prepared using the A549 lung cell line: control group, A. muricata leaf extract (AM), Methotrexate (MTX), AM-ChNPs, MTX-ChNPs, AM + MTX, and AM-ChNPs + MTX-ChNPs. 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide ( MTT) assay for testing cell cytotoxicity; gene expression of Caspase- 3; Bcl- 2; TNF- α; and Cyclin A genes. Cell cycle progress and the percentages of apoptosis and necrosis additionally were assessed. The combination of AM-ChNPs and MTX-ChNPs revealed clear action against A549 cancer cell line. The IC50 values for AM-ChNPs + MTX-ChNPs nano-group compared to AM + MTX group increased by 1.7 folds. Moreover, the apoptotic Caspase-3 gene expression was significantly upregulated by 8 folds. However, antiapoptotic Bcl-2 gene expression was unsignificantly downregulated by 0.16 folds. The inflammatory TNF-α gene expression was significantly upregulated by 6 folds, and the Cyclin A gene expression was downregulated by 0.29 folds, in the combination group of AM-ChNPs + MTX-ChNPs. An increase was discovered through flow cytometric analysis in the G2/M phase cell population driven into apoptosis. This study highlights on the combined effects on genotoxicity and cytotoxicity for both AM-ChNPs and MTX-ChNPs and their free forms; as well as their apoptogenic activities.
Vermicompost and Organic Manure Interactions: Effects on Heavy Metal Concentrations, Nitrification Activity, Comammox Nitrospira inopinata, and Archaea/Bacteria
Authors: Huda Nazmul , Rana Md. Rasel , Rahman M. Mizanur , Huq Md. Amdadul , Easmin Laboni , Rahman Shabiha Tasbir , Rahman Fahida , Rafi Meherab Hossain , Rauf Mamoona , Arif Muhammad 
Published: June 2023

Abstract
Vermicompost is a substantial source of nutrients, promotes soil fertility, and maintains or increases soil organic matter levels. Potentially toxic elements (PTEs) in vermicompost impact on nitrification activity. However, it is yet unknown how vermicompost affects nitrifying bacteria and archaea, comammox Nitrospira inopinata (complete ammonia oxidizers), net nitrification rates (NNRs), and PTEs. The effects of vermicompost application on NNRs, potential nitrification rates (NPs), PTEs, and the abundances of comammox N. inopinata bacteria, nitrite-oxidizing bacteria (NOB) and ammonia-oxidizing bacteria (AOB)/archaea (AOA) were studied. NNRs and NPs were significantly higher (p<0.05) in fresh cow-dung vermicompost (stored for 40 days) as compared with other organic manure. The level of PTEs (Cu2+, Fe2+, Pb2+, Cd2+, and Zn2+) was significantly lower (p<0.05)) in vermicompost as compared with compost of waste material with Trichoderma and cow-dung. Comammox N. inopinata, NOB, AOB, and AOA were significantly higher (p<0.05) in stored cow-dung vermicompost (more than one year) as compared with other organic manure. The results of the Scatter plot matrix analysis suggested that Fe2+, total nitrogen (TN), soil organic carbon (SOC), and total carbon (TC) were linearly correlated (p<0.001) with NNRs and NPs in vermicompost and organic manure. Similarly, comammox N. inopinata bacteria, NOB, AOB, and AOA were linearly correlated (p<0.001) with NNR and NP. It may be concluded that the influence of vermicompost, which played a great role in PTEs concentrations reduction, increased chemical and biological properties, increased the growth rate of nitrifying bacteria/ archaea and the nitrogen cycle.
CT Radiomics to Differentiate Between Wilms Tumor and Clear Cell Sarcoma of the Kidney in Children
Authors: Yaxin Deng , Ling He 
Published: June 2023

Abstract
Objective: To find out the role of contrast-enhanced CT radiomics in distinguishing pediatric Wilms' tumor (WT) from clear cell sarcoma of the kidney (CCSK).
Materials and Procudres: We retrospectively gathered the clinical information and preoperative CT images of 83 children with WT and 33 children with CCSK. In the renal parenchymal phase of contrast-enhanced CT, the maximum tumor diameter, the ratio of the maximum CT value of the solid portion of the tumor to the mean CT value of the contralateral renal vein (CTmax/CT renal vein), and the dilated peritumoral cysts were analyzed.
To extract radiomics features from arterial phase CT images, all patients were randomly divided into a training set (n=81) and a test set (n=35) in the ratio of 7:3.Sampling Technique (SMOTE) was used to handle imbalanced datasets, these radiomics features were then filtered using Pearson correlation coefficient and LASSO algorithm, and the filtered features were built into a machine learning based classifier model to calculate receiver operating characteristic curve (ROC), area under the ROC curve (AUC), 95% confidence interval (CI), accuracy, sensitivity and specificity.
Results: While there was no statistically significant difference between WT and CCSK in the test set (P>0.05), there was a statistical difference between the maximum tumor diameter (p=0.021) and dilated peritumoral cyst (p=0.005) in the training set. Nine radiomics features were used to develop the radiomics model, and machine learning based on logistic regression was chosen to build it.The cross-validation AUC was 0.888 (95% CI: 0.804-0.972), accuracy was 0.864, sensitivity was 0.826, and specificity was 0.879. The AUC for the test set was 0.784 (95% CI: 0.604-0.964), accuracy was 0.829, sensitivity was 0.600, and specificity was 0.920.The AUC for the training set was 0.901 (95% CI: 0.826-0.976), accuracy 0.889, sensitivity 0.826.
Conclusion: Radiomics of contrast-enhanced CT images is of diagnostic value in analyzing and differentiating WT and CCSK in children.
Multi-Step cutting parameter optimization method based on machining mechanism research of SiCp/Al
Authors: Zhang Xu , Hu Liangfei , Ge Jia , Xie Chaoyu , Zhang Xuechang 
Published: June 2023

Abstract
SiCp/Al composites are widely used in aerospace, automotive and other fields due to their excellent properties such as high dimensional stability and high specific strength. But, the large hardness of SiCp particles makes the processing of SiCp/Al difficult .The position of SiC particles relative to the cutting path determines the interaction bet ween the tool and the particles, which affects the cutting process of SiCp/Al. However, there is a lack of study on the position of SiC particles relative to the cutting path. We study the processing mechanism of SiCp / Al under multistep cutting and propose a model of the relative position of the cutting path and the SiCp particle. To reduce particle damage during the cutting process, a quantitative relationship between cutting depth and the diameter of SiC particles is established for the first time in this paper. Finite element models considering particle shape, distribution, and cohesive element are established based on the above model. The particle removal mechanisms, cutting force characteristics, and surface quality are compared in detail for multi-step and single-step cutting. The simulation model is validated through experiment. The results show that the optimized multi-step cutting parameters can change the removal mode of particles from overall debonding to local fracture, effectively reduce the machining defects, and finally improve the surface quality of the workpiece. The Ra and SSD depths are reduced by 41.1% and 27.9%, respectively, when compared to single-step cutting.
Biopolymer-amended-kaolin as a Barrier for Tailing Disposal Facilities
Authors: Yadav Himanshu , Venkata Bharat Tadikonda 
Published: June 2023

Abstract
Mining waste in tailing storage facilities contains high ionic strength salts that pose a potential threat to the environment. Kaolin clays are receiving great interest recently for engineered barriers as minimal shrinkage cracks occur in these 1:1 clays. The present study evaluates the hydraulic, volume-change, diffusion, and retardation characteristics of kaolin clay and xanthan gum amended clay under the hydro-chemo-mechanical loading conditions pertinent to the mine storage applications. A biopolymer, Xanthan Gum, was explored to amend the kaolin for the application of barrier to address the environmental concern. The barrier design parameters for tailing disposal facilities such as diffusion and retardation characteristics, were evaluated using the through-diffusion experiment. Diffusion tests were conducted on the samples obtained from the hydraulic permeation tests under mechanical loading to simulate the field conditions. Theoretical concentration profiles for both kaolin and xanthan gum amended kaolin barriers were obtained by the numerical simulation of the advection-diffusion equation using the finite difference method. The xanthan gum improved the chemical compatibility, reduced the hydraulic infiltration rate, and reduced diffusion rates significantly. The results from the study suggested the suitability of xanthan gum amended kaolin barrier for attenuation of contaminants and as a sustainable alternative in tailing disposal facilities.
Indigenous Land-based Activities as a Form of Health Resiliency: A Racialized Immigrant Family-based Learning
Authors: Datta Ranjan , Chapola Jebunnessa , Datta Prarthona , Datta Prikriti 
Published: June 2023

Abstract
Many visible minority immigrants and refugee communities are already experiencing inadequate access to education, and healthcare, lack of sufficient food, significantly higher rates of communicable and non-communicable diseases, and lack of access to essential services. Even when vulnerable communities can access healthcare services, they face stigma and discrimination. There is limited cross-cultural research examining the lived experiences of immigrant communities. Following a relational research framework, this study explores how learning and practicing Indigenous land-based practices were critical in building resilience for many racialized immigrant families during the pandemic. Our study shows Indigenous Land-based Mental Health Resiliency from Indigenous Elders and Knowledge-keeper’s land-based stories, traditional knowledge, resiliency, and practice may have many health benefits and positive outcomes in response to mental health disaster resiliency. Hope this study helps deconstruct the static vision of mental health disaster recovery and reconstruct community-led resiliency to the pandemic. It offers multiple mental health benefits and decolonizes mental health resiliency.
Exploring Access, Barriers, and Opportunities in Digital Health to Improve Sexual and Reproductive Health amongst Youths in Bamenda, Cameroon during Conflict: A Qualitative Study
Authors: Fonkwo Jaqueline Ngong , Agbor-Ntoh George Ashu , Besong Michael , Nouko Ariane , Akih Sinet , Wacha Roosevelt , Ngong Justin 
Published: June 2023

Abstract
Background:There exists several unmet sexual and reproductive health needs in sub-Saharan African countries like Cameroon. Youths in Bamenda, Northwest Region of Cameroon face particular difficulties accessing sexual and reproductive health services fully. This is partly due to the ongoing socio-economic crisis in the region which has disrupted provision of health care services, but also due to other issues that youths must contend with to access sexual and reproductive healthcare.
Methods: To explore this topic, we conducted a qualitative study. Two focus group discussions were done in Bamenda: One with boys and another with girls aged between 15-24 years old. Questions focused on access and use of sexual and reproductive health services like contraception, pregnancy, menstrual hygiene, sexually transmitted diseases, HIV, and gender-based violence. A thematic data analysis grouped data into themes and sub-themes.
Results: Twelve youth leaders participated in the focus group discussions: Three boys and nine girls. In this study, we found that several sexual and reproductive health services are available to youths. However, their ability to fully access these services is compromised by certain fundamental barriers like stigma and equally the socio-political crisis.
Conclusion: There are several barriers to sexual and reproductive services amongst youths in the conflict-affected town of Bamenda. Digital health can significantly bridge the gap to improve access to sexual and reproductive health.
Efficiacy of activated PMS/PDS by different methods in inactivating E.coli and P.aeroginosa
Authors: Eleren Sevil Çalışkan , Yavaş Ebru 
Published: June 2023

Abstract
The aim of the present study was to evaluate to efficacy of peroxydisulfate(PDS)/peroxymonosulfate(PMS) activated by different methods in inactivating E.coli and P.aeruginosa. The UV-A, UV-A/PDS or PMS and NaOH/PDS processes were used to inactivate E.coli and P.aeruginosa. Three different sulfate salts (K2S2O8, Na2S2O8 and Oxone) were used to activate with UV-A radiation and the inactivation effects were determined. During 30 minutes of UV A radiation, the addition of 3 mM K2S2O8, Na2S2O8, and Oxone increased the removal efficiency of E. coli by 1.76, 1.51, and 2.47 log, respectively. For P. aeruginosa, there was an increase of 1.44, 1.62, and 2.55 logs, respectively. The highest removal efficiency was obtained with oxone+UV-A on E.coli and P.aeroginosa. In order to examine the inactivation effect of alkaline (NaOH) activated peroxydisulfate on microorganisms, studies were carried out using two different doses of K2S2O8 (2 and 3 mmol/L). With the increase of PDS concentration, the removal efficiency for both bacteria increased. Higher removal efficiency was obtained at high base/PDS ratios. When the PDS concentration is increased from 2mM to 3mM at the same NaOH/PDS (0.25) ratio, the time required for 4 log bacteria removal is reduced by 33% for E.coli, while there is a decrease of more than 44.2% for P.aeroginosa.