bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of life in patients with progressive keratoconus treated with corneal collagen crosslinking
Authors: Steinberg Johannes , Fischer Paul , Frings Andreas , Druchkiv Vasyl , Katz Toam , Linke Stephan J 
Published: July 2023

Abstract
Purpose
To analyze the vision-related quality of life (vr-QoL) in keratoconus (KC) patients after corneal crosslinking (CXL).
Methods
In this prospective clinical study, next to comparing the morphology and functional parameters of KC patients, we applied the “National Eye Institute Visual Functioning Questionnaire” (NEI-25) and the “Keratoconus Outcomes Research Questionnaire” (KORQ) to analyze the vr-QoL in 41 patients before, three and six months after CXL. Rasch analyses was applied to verify the measurement precision of the KORQ in our study population.
Results
We did not find statistically significant changes of the corneal morphology and the best corrected visual acuity after CXL. The NEI-25 questionnaires did not show statistically significant changes throughout the follow-up period. Except from single items, the main scores of the KORQ also did not demonstrate statistically significant changes. Rasch analyses revealed a high measurement precision of the KORQ within our population.
Conclusion
We could demonstrate a stable (not-improving) vr-QoL after CXL in patients with progressive KC. Based on our findings we suggest very early CXL treatment in KC patients that are at high risk of progression.
Prediction of Hydration Properties and Microstructure Development of Cement Mortar Using Virtual Cement and Concrete Testing Laboratory
Authors: Rastogi Hrishika , Moharana Sumedha , Subhash Smrithy 
Published: July 2023

Abstract
Hydration of cement is a complex phenomenon involves a simultaneous interaction between various compounds at the microscopic level. The proper monitoring of the hydration process of cement provides a better understanding of the hydration mechanism of build concrete along with increased workability, durability, and strength. The experimental techniques adopted for determining hydration and mechanical properties of cement compounds can be modelled using computational modelling tools such as the Virtual Cement and Concrete Testing Laboratory (VCCTL). This study mainly aims to predict the properties of ordinary Portland and pozzolanic cement mortar indigenous to India using VCCTL. The material data required as input parameters for creating virtual cement and fly ash are obtained from the previous studies. The calculated hydration and strength properties, such as heat of hydration, chemical shrinkage, degree of hydration, compressive strength and microstructure development of previous studies are validated using the VCCTL.
What exactly does the PfK13 mutation in Plasmodium falciparum change?
Authors: Si Wenwen , Zhao Yuemeng , Qin Xixi , Huang Yixuan , Yu Jing , Liu Xiao , Li Yanna , Yan Xiaoli , Zhang Qingfeng , Sun Jun 
Published: July 2023

Abstract
The emergence and development of artemisinin resistance threaten global malaria control and elimination goals, thereby prompting research on the mechanisms of malaria parasite resistance. The mutation of Plasmodium falciparum Kelch 13 ( PfK13) protein is associated with artemisinin resistance, but the unique or common mechanism by which it leads to this resistance is unclear. By analyzing the different effects of PfK13 mutation on the P. falciparum transcriptome and proteome at the different stages, we found that PfK13 mutation did not significantly change glycolysis, TCA, pentose phosphate pathway (PPP) and oxidative phosphorylation but reduced the expression of reproduction- and DNA synthesis-related genes. Moreover, the reduced number of the merozoite, decreased amount of hemozoin, and slowed growth of P. falciparum 3D7C580Y were consistent with the changes, suggesting that the PfK13 mutation reduces hemoglobin ingestion, leading to artemisinin resistance, likely by decreasing the parasites' need for haem and iron. This study helps elucidate the mechanism of artemisinin resistance caused by the PfK13 mutation.
Robust adaptive Control for the DC-DC Buck-Boost Converter
Authors: Oucheriah Said 
Published: July 2023

Abstract
A robust adaptive nonlinear controller is developed to tightly regulate the output voltage of the inverting buck- boost converter, a non-minimum phase system that presents major challenges in the design of stabilizing controllers. An observer is used to estimate the unknown load conductance. A rigorous stability analysis of the nonlinear closed-loop system is performed. The output of the converter is always guaranteed to converge to the desired voltage by a judicious choice of the initial conditions of the estimator. Simulation results are presented to validate the effectiveness of the proposed controller and to compare its performance against a novel robust proportional- integral (PI)-type controller
Results Relating to the Existence of Solutions for Partial Differential-difference Fermat Type Equations in Cn
Authors: MONDAL RANA , KAISH IMRUL 
Published: July 2023

Abstract
Our study looks into the non-existence of transcendental entire solutions for partial differential-difference equation of Fermat typef(z)∂f(z)∂z1+∂f(z)∂z2+ .... +∂f(z)∂znm+ f(z + c)l = 1,where l, m are positive integers and c = (c1, c2, ...., cn) ∈ Cn\{0} with finite order constraintin Cn. Additionally, using the Nevanlinna theory of meromorphic functions in various complex variables, this article examines the existence and an explicit form of solutions to several Fermat-type partial differential-difference equations in Cn. We obtain conclusions about the existence and form of transcendental entire solutions for specific class of functional equation of the type of Fermat with more general form ofαf(z) + β1∂f(z)∂z1+ β2∂f(z)∂z2+ .... + βn∂f(z)∂zn2+ f(z + c)2 = eg(z),where α, βj (j = 1, 2, ..., n) are constants in C and g(z) form a polynomial in Cn with a finite order constraint. The conclusions offered as solutions to these equations have significantly improved the theorems previously proposed by Xu, Cao, Liu, Wang, Zhang, and Zheng [17, 32, 33, 34, 35]. The method used in this article is different from the one used in previous ones. The existence conditions and forms of transcendental entire solutions with a finite order of such equations are demonstrated by providing several examples.
2010 Mathematics Subject Classification. 30D35.
A Probabilistic Framework for Post-Disaster Recovery Modeling of Buildings and Utility Networks in Developing Countries
Authors: Opabola Eyitayo , Galasso Carmine 
Published: July 2023

Abstract
Post-disaster recovery is a significant challenge, especially in developing countries. Various technical, environmental, socioeconomic, political, and cultural factors substantially influence post-disaster recovery. As a result, methodologies relevant in developed nations may not be directly applicable in Global South contexts. This study introduces a probabilistic framework for modeling the post-disaster recovery of buildings and utility networks in developing countries. The proposed framework combines a building-level assessment of individual assets with a community-level assessment of utility networks to evaluate the post-disaster functionality state of a building portfolio. As part of the framework, a stochastic network analysis approach is proposed to estimate the recovery time of damaged buildings while accounting for technical, environmental, socioeconomic, political, and cultural factors, quantified using data gathered from past events. Similarly, a probabilistic modeling approach is proposed to quantify the utility network’s initial post-disaster outage levels. Specifically, empirical formulations for estimating the recovery time of an electric power network as a function of its initial post-disaster outage levels are calibrated using post-event data from developing countries. A case study is presented to illustrate the application of the proposed framework to model the post-earthquake recovery of a synthetic low-income residential community. The analysis showed that negative technical, environmental, socioeconomic, political, and cultural factors could amplify the reconstruction time of damaged buildings by a factor of almost three. The proposed framework can support decision-makers in disaster planning and management strategies for vulnerable low-income communities.
An algorithm for generating uplink complex nonorthogonal multiple access spreading codes to reduce execution time
Authors: amir  
Published: July 2023

Abstract
Non-orthogonal multiple access (NOMA)-assisted 5G wireless communication networks in uplink and downlink transmissions can provide the high demands of low latency, high data rate, massive connectivity, and high access speed without compromising security. Algorithms to produce minimal coherence (cross-correlation) codebooks are desired in various applications. The authors built an algorithm capable of generating complex NOMA spreading codes based on the equiangular tight frame (ETF) method. Execution time is one of the computer science terms that refer to the various stages of running software programs and determining the performance of programs. The created algorithm was reasonably fast to find a sufficient number of NOMA spreading codes that have the minimum cross-correlation. It modified the initial value with the algorithm to reduce execution time and generate complex value-spreading codes. This algorithm achieved the optimal cross-correlation for multiple access and implemented the lowest running time compared to the "best complex antipodal spherical code" (BCASC) method, the "approximate nearest neighbors’ best complex antipodal spherical code" (ANN BCASC) method, the "Dhillon et al" method, the "Medra et al" method, the "coherence-based Grassmannian codebook" (CBGC) method, the “Grassmannian package” method, the “original best complex antipodal spherical code" (ORIG-BCASC) method, and the "Grassmannian package" method. The algorithm achieved optimal coherence (maximum cross-correlation) for matrix dimension (m, n), where m, n denotes the size of the collection set of vectors in the Frame. The optimal coherence (maximum cross-correlation) is 0.4472 for (3, 6), 0.4714 for (3, 7), 0.3536 for (4, 7), 0.3780 for (4, 8), 0.4472 for (4, 16), 0.3333 for (5, 10), 0.3464 for (5, 11), 0.4082 for (5, 25), 0.2500 for (6, 9), 0.2887 for (6, 11), 0.3015 for (6, 12), and 0.3333 for (7, 28) with an enhancement the parameters number of iterations and tolerance value in time less than one second. Also, superior to the “Grassmannian package” method in execution time, also the execution time for BCASC, CBGC, and ORIG-BCASC methods was more than one second. The performed simulations verified the uplink spectral efficiency and total capacity rate after applying the spreading codes generated from the suggested algorithm. In conclusion, the proposed algorithm for generating NOMA spreading codes tokens based on complex ETFs and exported from our algorithm provided better performance and capacity than other multi-access signatures.
Inklusionssensible Lehrer*innenbildung goes digital. Forschung, Entwicklung und Strukturbildung von digitalisierten Aus-, Fort- und Weiterbildungsangeboten an der Universität Bielefeld
Authors: Schuldt Alessa , Lütje-Klose Birgit , Streblow Lilian , Heinrich Martin 
Published: July 2023

In den vergangenen Jahren hat die fortschreitende Digitalisierung sämtliche Bereiche des gesellschaftlichen Lebens nachhaltig beeinflusst und verändert. Dies hat auch Auswirkungen auf unser Bildungssystem und geht mit vielfältigen Fragestellungen einher. So verwundert es aufgrund der zunehmenden Aktualität der Thematik nicht, dass ein reger bildungspolitischer und erziehungswissenschaftlicher Diskurs entfacht wurde, der sich mit den Herausforderungen und Chancen von digitaler Bildung befasst. Da durch den Einsatz digitaler Medien die Möglichkeit besteht, gesellschaftliche Teilhabebarrieren zu minimieren, werden die Themen Inklusion und Digitalisierung in jüngster Zeit immer häufiger im Verbund diskutiert. In Bezug auf die Lehrer*innenbildung stellt dabei vor allem die digitalgestützte Qualifikation für Inklusion noch ein Desiderat dar. Hieran anknüpfend stellt der folgende Beitrag Strategien der Digitalisierung in der inklusionssensiblen Lehrer*innenbildung an der Universität Bielefeld vor. Ausgehend von den standortunabhängigen wie auch -spezifischen Ausgangslagen sowie den Einstellungen und Interessen von Lehramtsstudierenden gegenüber dem Thema Digitalisierung wird der aktuelle Ist-Zustand an digitalen Aus-, Weiter- und Fortbildungsmaßnahmen am Hochschulstandort Bielefeld skizziert und der Stellenwert von digitalen Medien im Kontext der hochschulinternen Strukturentwicklung hervorgehoben.

Abstract
During the past few years the impact of digitalisation has had a huge impact on all areas of social life as our education system, for instance. Thus, it is not surprising that a lively discussion is being held that deals with the challenges and opportunities of digital education is conducted in the fields of education policy and educational sciences. Since the use of digital media offers the possibility of minimising barriers to participation in society, it might be meaningful to combine the discourses facing the topics of inclusion and digitalisation in terms of teacher education. However, digitally supported (pre-service) teacher trainings for an inclusive teacher education is a significant research gap which should attract more attention and research efforts. Based on this the following article presents strategies for the digitisation of an inclusion-sensitive teacher education as they are developed and used at Bielefeld University. So, the article gives a practical overview of how to combine the issues of digitisation and inclusion in order to build up a digital infrastructure for teacher education purposes.
Ecología trófica y reproductiva del bagresito endémico Trichomycterus nigromaculatus (Siluriformes: Trichomycteridae) en el río Gaira, Colombia
Authors: Ibarra-Trujillo Eduardo J. , García-Alzate Carlos A. 
Published: July 2023

El río Gaira, en Minca, SNSM, sufre una transformación acelerada de sus paisajes naturales, fomentada por actividades como el turismo y la agricultura. Esto es preocupante considerando que allí habita una diversidad de especies endémicas como el pez Trichomycterus nigromaculatus. El objetivo del trabajo fue analizar aspectos de la dieta y la reproducción de T. nigromaculatus. Para ello, se realizaron siete muestreos abarcando periodos hidroclimáticos del área de estudio. Los peces fueron capturados empleando una red de arrastre y una atarraya, y las variables fisicoquímicas se midieron in situ. Durante el estudio se analizó el contenido estomacal de 245 ejemplares de T. nigromaculatus a través de métodos numéricos, volumen y frecuencia de ocurrencia. Se calcularon factores como el índice de importancia alimentaria, el coeficiente de vacuidad, la amplitud del nicho trófico, el factor de condición y la sección reproductiva. Asimismo, se determinaron la proporción de sexos, índice gonadosomático, fecundidad, tallas mínima y media de madurez sexual y diámetro de los ovocitos. El río Gaira, considerado mesotrófico con tendencia a la eutrofización, presentó un aumento del pH y la conductividad eléctrica del agua. Con respecto a la dieta de T. nigromaculatus, el coeficiente de vacuidad de los ejemplares fue de 13,88 %, y se observó un comportamiento omnívoro con principal consumo de larvas Simulium sp. e insectos. El factor de condición indicó que la especie estuvo bien alimentada. Se identificó una proporción sexual 1:1,5, con 73 machos y 50 hembras. Los machos alcanzaron la talla media de madurez sexual a los 90,46 mm (LE), y las hembras, a los 63,0 mm (LE ). La relación gonadosomática indicó tres eventos reproductivos, en los que la fecundidad fue menor en bajas lluvias, con 194 ovocitos, y mayor en altas lluvias, con 369. El diámetro del ovocito fue de 0,07 mm en promedio.
Recent Update on the Protective Potentials of Resveratrol against
Cisplatin-induced Ototoxicity: A Systematic Review
Authors: Alsaikhan Fahad , Jasim Saade Abdalkareem , Margiana Ria , Opulencia Maria Jade Catalan , Yasin Ghulam , Hammid Ali Thaeer , Nasretdinova Makhzuna Tahsinovna , Mahdi Ahmed B. , Farhood Bagher , Abedi-Firouzjah Razzagh , Jamialahmadi Tannaz , Sahebkar Amirhosein 
Published: July 2023

Introduction:
Although cancer treatment with cisplatin is effective, dose-dependent adverse
effects such as ototoxicity occurs often, which limits its clinical use. The use of resveratrol
may alleviate the cisplatin-induced ototoxic effects. This study is aimed to review the potential otoprotective
effects of resveratrol against cisplatin-induced ototoxicity.

Method:
According to the PRISMA guideline, a systematic search was accomplished to identify
all relevant scientific papers on “the role of resveratrol against cisplatin-induced ototoxicity” in different
electronic databases up to May 2021. Fifty-five articles were screened based on a predefined
set of inclusion and exclusion criteria. Eight eligible studies were finally included in the
current systematic review. The in-vitro findings revealed that cisplatin administration significantly
decreased the HEI-OC1 cell viability compared to the untreated cells; however, resveratrol co-treatment
(in a dose-dependent manner) could protect HEI-OC1 cells against cisplatin-induced decrease
in cell viability.

Results:
Furthermore, the in-vivo finding showed a decreased value of DPOAE, and increased values
of ABR threshold, ABR-I, ABR-IV, and ABR I-IV interval in cisplatin-treated animals; in contrast,
resveratrol co-administration demonstrated an opposite pattern on these parameters.

Conclusion:
Thus, it can be mentioned that resveratrol co-treatment alleviates cisplatin-induced
ototoxicity. Mechanically, resveratrol exerts its otoprotective effects through various mechanisms
such as anti-oxidant, anti-apoptosis, and anti-inflammatory.
Group A β-hemolytic Streptococcal Pharyngitis: An Updated Review
Authors: Leung Alexander K.C. , Lam Joseph M. , Barankin Benjamin , Leong Kin F. , Hon Kam L. 
Published: July 2023

Background:
Group A ß-hemolytic Streptococcus (GABHS) is the leading bacterial cause of acute pharyngitis in children and adolescents worldwide.

Objective:
This article aims to familiarize clinicians with the clinical manifestations, evaluation, diagnosis, and management of GABHS pharyngitis.

Methods:
A search was conducted in December 2022 in PubMed Clinical Queries using the key term “group A β-hemolytic streptococcal pharyngitis”. This review covers mainly literature published in the previous ten years.

Results:
Children with GABHS pharyngitis typically present with an abrupt onset of fever, intense pain in the throat, pain on swallowing, an inflamed pharynx, enlarged and erythematous tonsils, a red and swollen uvula, enlarged tender anterior cervical lymph nodes. As clinical manifestations may not be specific, even experienced clinicians may have difficulties diagnosing GABHS pharyngitis solely based on epidemiologic or clinical grounds alone. Patients suspected of having GABHS pharyngitis should be confirmed by microbiologic testing (e.g., culture, rapid antigen detection test, molecular point-of-care test) of a throat swab specimen prior to the initiation of antimicrobial therapy. Microbiologic testing is generally unnecessary in patients with pharyngitis whose clinical and epidemiologic findings do not suggest GABHS. Clinical score systems such as the Centor score and McIssac score have been developed to help clinicians decide which patients should undergo diagnostic testing and reduce the unnecessary use of antimicrobials. Antimicrobial therapy should be initiated without delay once the diagnosis is confirmed. Oral penicillin V and amoxicillin remain the drugs of choice. For patients who have a non-anaphylactic allergy to penicillin, oral cephalosporin is an acceptable alternative. For patients with a history of immediate, anaphylactic-type hypersensitivity to penicillin, oral clindamycin, clarithromycin, and azithromycin are acceptable alternatives.

Conclusion:
Early diagnosis and antimicrobial treatment are recommended to prevent suppurative complications (e.g., cervical lymphadenitis, peritonsillar abscess) and non-suppurative complications (particularly rheumatic fever) as well as to reduce the severity of symptoms, to shorten the du-ration of the illness and to reduce disease transmission.
THE IMPLEMENTATION OF VIRTUAL REALITY (VR) TECHNOLOGY IN REAL ESTATE INDUSTRY
Authors: Sahray Kholim , Sukereman Anis Syazwani , Rosman Siti Hasniza , Jaafar Nur Hanis 
Published: July 2023

COVID-19 pandemic impact has accelerated the real estate industry to adopt technology evolution quickly. Due to the normalisation changes from the pandemic, all the physical real estate selling processes, including housing tours, sales, and purchase agreements, could not be effectively done as before. In this situation, Virtual Reality (VR) has become a prominent approach for real estate agents to improve their marketing strategies. This prospective study was designed to investigate the potential activities needed in VR implementation and to explore the importance of VR in influencing real estate marketing. Primary data was gathered from 60 real estate respondents using purposive sampling and descriptively analysed using SPSS software. The findings indicate that VR tours of the property, 360-degree visualisations, and visualisations of room furniture are the most potential activities needed in VR implementation. While VR is important because it indicates detailed information about the property, provides high-quality photos, and is a good investment opportunity. Overall, this study provides insights into how VR technology can help realtors survive in the evolving real estate industry.
Rapid Expansion of a Teledermatology Web Application for Digital Dermatology Assessment Necessitated by the COVID-19 Pandemic: Retrospective Evaluation
Authors: Muthiah Shareen , Craig Fiona E , Sinclair Siobhan , Wylie Grant , Torley Donna , Wong Terence H , Morton Colin A 
Published: July 2023

Background
The COVID-19 pandemic necessitated a change in the provision of outpatient care in dermatology.

Objective
A novel, asynchronous, digital consultation platform was codeveloped with 2 National Health Service dermatology teams to improve access and enhance choice in outpatient care.

Methods
The rollout of the platform was accelerated during the initial COVID-19 lockdown, and its wider use across 2 Scottish health boards was retrospectively evaluated. Integrated with the hospital booking system and electronic patient record, the platform provides an alternative to face-to-face consultations, using information and images submitted by the patients.

Results
In total, 297 new patient consultations and 108 return patient consultations were assessed, and 80% (324/405) of the images submitted were of satisfactory quality. The consultations were, on average, 3 minutes shorter than equivalent face-to-face interactions, and a total of 5758 km of patient travel was avoided. Outcomes included web-based reviews (66/405, 16.3%), face-to-face reviews (190/405, 46.9%), biopsies (46/405, 11.4%), discharge (89/405, 22%), and other treatments or investigations (14/405, 3.5%). High levels of patient satisfaction (92/112, 82.1%) were reported.

Conclusions
Digital dermatology assessments are now included in the choices for consultation types that are available to patients, helping to augment service capacity during pandemic recovery.