bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel framework for analyzing urban water network events and determining the optimal location of urban drinking water relief posts
Authors: Garajeh Mohammad Kazemi 
Published: July 2023

Abstract
Urban water is known as critical sector of urban environments which significantly impacts the life quality and wellbeing of reinstates. In the context of developing sustainable urban drinking system it is critical to analysis network events and develop sufficient systems of water supply. In following this objective, the current study aims to propose an efficient approach for Geospatial based urban water network events analyze and determine the optimal location of urban drinking water relief posts in Zanjan. For this goal, first, we prepared and preprocessed various predisposing variables such as water storage sources, pump stations, traffic density, population density, road network, land use, subscribers, areas with higher water pressure, and accident-prone areas for analyzing the urban water network events and determining the optimal location of urban drinking water relief posts. We then applied an integrated approach of analytical network process (ANP) and deep learning convolutional neural network (DL-CNN) data-driven methods to locate the optimal place of urban drinking water relief posts. Finally, intersection over union and accuracy assessment were employed to evaluate the performance of the results. Our findings show that the DL-CNN performed well with the accuracy of 0.942 than the ANP (0.895) for determining the optimal location of urban drinking water relief posts. The results indicate that the most suitable places for building a relief post are in the center of the city and its surrounding areas might not suitable due to barren lands and sparse population. The results of the study also reveal that areas 5 and 3 are at high risk from the number of urban water network incidents perspective, which require the construction of urban water relief stations.
Can Diode Laser 810 decrease Post Endodontic Pain in Patients with Asymptomatic Necrotic Maxillary Incisors? A Four-Arm Randomized Controlled Trial
Authors: Abbara Mohammad Tamer , Tolibah Yasser Alsayed , Akil Samar , Hamadah Omar , Achour Hassan , Mahayni Ghina 
Published: July 2023

AbstractBackground and aim: In light of the development of modern technologies and the insertion of laser in the context of endodontic treatment, this study aimed to find the best method for applying the 810 diode laser to relieve post-endodontic pain on necrotic maxillary incisors with periapical lesions within a single-visit treatment. Methods: Eighty patients with a necrotic incisor, diagnosed with asymptomatic periodontitis, received standardized cleaning and shaping procedures, then divided equally into four groups: G1: control group with no laser application, G2: applying the diode laser as an irrigation activation system (IAS), G3: applying the diode laser from the buccal and palatal mucosa, G4: applying the diode laser as an IAS and from buccal and palatal mucosa. The postoperative pain (PP) was assessed using the visual analog scale (VAS) 1, 3, 7, and 14 days after the treatment. The mean values of the VAS score were statistically analyzed. Results: During 14 days after treatment, there was a statistically significant difference between mean values of VAS scores in the four groups (P value < 0.05); G1 scored the highest score, whereas G4 showed the lowest one. Moreover, G4 showed favorable outcomes compared with G2 and G3 during the first three days after treatment. Conclusion: Diode laser reduced the PP after necrotic teeth with large-sized apical lesion treatment, whereas using diode laser either as an IAS or LLLT reduced the PP compared with the control group. Moreover, the usage of a diode laser in both previous techniques represents the best protocol for PP relieve during 14 days of treatment.
Factors of geographical variability of antimicrobial use in Japan
Authors: Kitano Taito , Tsuzuki Shinya , Koizumi Ryuji , Aoyagi Kensuke , Asai Yusuke , Kusama Yoshiki , Ohmagari Norio 
Published: July 2023

Abstract
Background
The evidence regarding the factors affecting the geographical variation of antimicrobial use (AMU) is relatively scarce. The study aimed to evaluate factors potentially associated with geographical variability of AMU per day per 1,000 habitants in 47 prefectures of Japan.
Methods
This is an observational ecological study using the Japanese national database in 2019. The outcome was the defined daily doses per 1,000 inhabitants per day by prefecture. The multivariable negative binomial regression analysis was conducted using patient- and physician-level variables.
Results
The study included 605,391,054 defined daily doses of AMU in 2019 from the 47 prefectures. In the multivariable negative binomial regression analyses for the outcome of total AMU, the proportion of females (RR 1.04 [1.01 − 1.08] per 1% increase, p = 0.021), the proportion of upper secondary graduates going to further education (RR 1.01 [1.00 − 1.01] per 1% increase, p = 0.005) and the annual number of diagnoses related with upper respiratory infections (URIs) per 1,000 inhabitants per day (RR 1.21 [1.10 − 1.34], p < 0.001) were significantly correlated with total AMU.
Conclusions
In the ecological study, the variability of total AMU by Japanese prefecture was associated with the proportion of females, the education level and the number of URI diagnoses per population. The results suggest the potential need for additional stewardship efforts to reduce unnecessary antimicrobial prescriptions for URI.
The Effects of Nozzle Diameter and Length on the Resulting Strand Properties for Shotcrete 3D Printing
Authors: David Martin , Freund Niklas , Dröder Klaus , Lowke Dirk 
Published: July 2023

Abstract
Additive Manufacturing in Construction (AMC) enables new design methods and strategies within the construction industry. In particular, Shotcrete 3D Printing (SC3DP) offers a high degree of design freedom by enabling the deposition of concrete at variable layer orientation based on a wet-mix shotcrete process. However, the mechanical properties and geometry of the printed layers are dependent on the material and process parameters used. In this context, the effects of air and concrete flow rates, path planning parameters, and material parameters have been investigated in previous research. The here presented study investigates the influence of the nozzle geometry on the resulting strand properties, e.g. strand geometry, layer bond strength, and compressive strength, to evaluate nozzle diameter and length as control parameters for the SC3DP process. Experimental investigations were performed with fixed nozzle diameters between 10 and 30 mm and nozzle lengths ranging from 100 to 200 mm. The results show a significant influence of the nozzle diameter on the resulting strand geometry as well as the mechanical properties. Finally, concepts for a nozzle with a controllable outlet diameter were developed and evaluated.
Construction of a near infrared fluorescence system for blood flow imaging of biological tissues
Authors: Zhao Xu , Li Shilin , Song Yue , Fan Lianhui 
Published: July 2023

Abstract
Background
Intraoperative real-time imaging of tissue or blood vessels has certain technical advantages for surgical procedures. But due to various reasons, this technology has not been popularized.
Objective
The purpose of this study is to construct an equipment to apply Indocyanine Green Video Angiography (ICGVA) technology to many practical clinical works.
Methods
ICG was injected into bilateral renal pelvises of the 10 male rabbits and the images of the ureter and bladder were captured. ICG was injected into the ear vein of the other 10 male rabbits, and the images of small intestine were captured.
Results
Through this equipment, we obtained visible light image, near-infrared fluorescence image, and fusion image of the ureter, bladder and intestine.
Conclusion
We constructed and optimized a set of portable and flexible vascular and tissue fluorescence imaging equipment. This equipment can be used for animal experiments, determination of the degree of trauma and intraoperative tissue localization and navigation.
Exploring the sustainable reporting practices of universities in relation to the United Nations’ 2030 Agenda for sustainable development
Authors: Nikolaou Ioannis , Tsalis Thomas , Trevlopoulos Nikolaos , Mathea Anna , Avlogiaris Georgios , Vatalis Konstantinos 
Published: July 2023

Abstract

Many universities have recently adopted various practices to promote the aims and principles of sustainable development, such as greening their curriculum, enhancing the environmental performance of their campus and using sustainable criteria in their investment and purchasing behavior. Relatively recently, the definition of the sustainable development was broadened by the introduction of 17 Sustainable Development Goals (SDGs) proposed by the United Nations’ (UN) 2030 Agenda which stipulates the new directions for sustainability at global level. Given this background, this paper examines the level of alignment of universities with the 17 SDGs through an analysis of sustainability reports prepared by universities in order to highlight the issues which are mostly discussed by universities in relation to SDGs. To do so, an empirical analysis was carried out on a sample of 37 sustainability reports using a methodological framework based on scoring techniques to analyze their content. The findings show that the universities have disclosed more information about climate change mitigation and adaptation practices and less about SDGs regarding quality of education and peace, democracy and strong institutions.
Portable visual and electrochemical detection of hydrogen peroxide release from living cells based on dual functional Pt-Ni hydrogels
Authors: Wen Dan , Li Guanglei , Chen Yao , Liu Fei , Bi Wenhua , Wang Chenxin , Lu Danfeng 
Published: July 2023

Abstract
It is of great significance to monitor the intra-/extra-cellular concentration of hydrogen peroxide (H2O2) in biological processes. However, miniaturized devices that realize portable and accurate H2O2 detection are still at an infant stage because of the difficulties to develop facile sensing strategies and further highly-integrated sensing devices. In this work, portable H2O2 sensors are demonstrated based on Pt-Ni hydrogels with excellent peroxidase-like and electrocatalytic activities. Thus, simple and sensitive H2O2 sensing is achieved through both colorimetric and electrochemical strategies. The as-fabricated H2O2 sensing chips exhibit favorable performances such as low detection limits (0.03 μM & 0.15 μM), wide linearity ranges (0.1 μM-10 mM & 0.5 μM-5 mM), outstanding long-term stability (up to 60 days), and excellent selectivity. With the aid of an M5stack development board, portable visual and electrochemical H2O2 sensors are successfully constructed without complicated and expensive equipment as well as professional operators. When applied in the H2O2 detection released from the Hela cells, the obtained results are in good agreement with those from an ultraviolet-visible spectrophotometer (UV-vis) (1.97 μM vs. 2.08 μM) and electrochemical station (1.77 μM vs. 1.84 μM), respectively.
Timing of COVID19 vaccination drives menstrual cycle changes
Authors: Edelman Alison , Boniface Emily , Male Victoria , Cameron Sharon , Benhar Eleonora , Han Leo , Matteson Kristen , Lamsweerde Agathe van , Pearson Jack , darney Blair 
Published: July 2023

Abstract
COVID-19 vaccination temporarily lengthens the menstrual cycle. However, without knowing why this happens, we are limited in our ability to fully address ongoing concerns around menstrual health and COVID-19 vaccination. We assessed whether menstrual cycle timing (follicular or luteal phase) of COVID-19 vaccine administration is driving vaccine-associated cycle length changes. We used prospectively collected (2021-2022) menstrual cycle tracking data from 19,497 reproductive-aged users of the application ‘Natural Cycles’. We identified whether vaccine was delivered in the follicular or luteal phase and also included an unvaccinated control group. Our primary outcome was the adjusted within-individual change in cycle length (in days) from the average of the three menstrual cycles prior to the first vaccination cycle (unvaccinated controls were assigned a notional vaccine date). We also assessed if a clinically significant change in cycle length occurred (8 days or more). Individuals were mostly under age 35 (80.1%), and from North America (28.6%), continental Europe (33.5%) or the UK (31.7%). In the vaccinated group, the majority received an mRNA vaccine (63.8%). Individuals vaccinated in the follicular phase experienced an average 1-day longer adjusted cycle length with both a first or second dose of COVID-19 vaccine compared to their pre-vaccination average [1st dose: 1.00 day (98.75% CI 0.88, 1.13), 2nd dose 1.11 days (98.75% CI 0.93, 1.29)] whereas those vaccinated in the luteal phase and the unvaccinated control group experienced no change in cycle length [respectively, 1st dose -0.09 (-0.26, 0.07), 2nd dose 0.06 (-0.16, 0.29), unvaccinated notional 1st dose 0.08 (-0.10, 0.27), 2nd dose 0.17 (-0.04, 0.38). Those vaccinated during the follicular phase were also more likely to experience a clinically significant change in cycle length (>8 days; 1st dose: 6.8%) than those vaccinated in the luteal phase or unvaccinated (3.3% and 5.0%, respectively; p < 0.001). COVID-19 vaccine-related cycle length increases are associated with receipt of vaccination in the first half of the menstrual cycle (follicular phase) which is consistent with other known immune-related events (e.g. fever) that also cause temporary cycle length changes.
Lagged teleconnections between two types of ENSO and Southeast Asian autumn rainfall anomalies
Authors: Nguyen-Le Dzung , Ngo-Duc Thanh , Matsumoto Jun 
Published: July 2023

Abstract
The lagged teleconnections of the two types of El Niño–Southern Oscillation (ENSO) on Southeast Asian autumn rainfall (SEAAR) anomalies for lagged time varying from 12 to zero months are investigated for the period 1979 to 2019 using Singular Value Decomposition (SVD) and composite analyses. It shows that the first two SVD coupled modes always exhibit the patterns of the two types of ENSO for all lagged times. First, the canonical El Niño (EN) from preceding autumn induces significantly wetter SEAAR, due to the transition from EN to La Niña (LN) in the following year. Thereafter, disparities between ENSO and ENSO Modoki teleconnections on SEAAR are most pronounced for the 6-month lag, in which an El Niño Modoki (EM)/La Niña Modoki (LM) occurring in the preceding spring is a strong indication of a much drier/wetter SEAAR. Subsequently, for 3-month and zero lag, both EN and EM (LN and LM) bring drier (wetter) SEAAR. However, EM leads to drier (wetter) conditions in the north (south). Regarding LN and LM, LM causes significantly less rainfall in the Philippines, northern Indochina, and Sumatra. The differences in SEAAR anomalies under ENSO and ENSO Modoki conditions are linked to a more northward (southward) Walker circulation in EM compared to EN (LM compared to LN). Different evolution patterns, i.e., transition from EM to LM occurs less frequently than EN to LN, particularly with preceding autumn and spring ENSO events, contribute to the distinct lagged teleconnections between the two ENSO types. It also results in longer teleconnection persistence of LM and LN compared to EM and EN.
Derivation of clinical predictive factors (CHIEF) for first recurrent Clostridioides difficile infection
Authors: Mori Nobuaki , Hirai Jun , Ohashi Wataru , Asai Nobuhiro , Shibata Yuichi , Mikamo Hiroshige 
Published: July 2023

Abstract
Purpose: High Clostridioides difficile infection (CDI) recurrence rates pose a significant health threat and economic burden. Effective prevention strategies are crucial, and clinical prediction rules can help identify risk factors for CDI recurrence. However, existing models are limited in accounting for important risk factors. This study aimed to develop a practical clinical prediction rule for CDI recurrence.Methods: This retrospective cohort study was conducted on the medical records of patients with CDI at Aichi University Hospital in Japan. Variables including age, sex, underlying diseases, antibiotic use, acid suppressants, immunosuppressants, and CDI history were analyzed. CDI severity and recurrence rate were also assessed. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to identify significant recurrence predictors.Results: In total, 209 patients were included in the study, 45 of whom developed recurrent CDI. Univariate analyses identified several significant recurrence predictors, including enteral feeding, inflammatory bowel diseases (IBD), community-onset CDI, and severe CDI. Multivariate analysis revealed enteral feeding (odds ratio [OR]: 3.87, 95% confidence interval [CI]: 1.75–8.56) and IBD (OR: 7.08, 95% CI: 1.28–39.06). The CHIEF predictive scoring system was developed using five relevant variables: carbapenem use, hematologic malignancy, IBD, enteral feeding, and fluoroquinolone use. The area under the ROC curve for the CHIEF score was 0.70.Conclusions: The CHIEF score incorporates useful, clinically available factors and could help identify patients at risk of recurrent CDI. These findings contribute to the understanding of recurrence risk factors and support the development of prevention strategies.
Effect of different cervical curvatures on three-dimensional kinematics under physiological load
Authors: Zhang Zizhen , Zhong Yanlong , Luo Shiwei , Yang Jie , Chen Shaofeng , Chen Gongxin , Li Jidong , Li Guoan , Wang Shaobai , Wan Zongmiao 
Published: July 2023

Abstract
Objective: The aim of this study was to measure the 3D motion of cervical vertebra with different curvatures under seven functional postures and investigate the relationship between cervical spine curvatures and the kinematics of each functional motion unit.
Methods: Seventy-five volunteers were classified into 5 curvature groups based on the C1-C7 Cobb angle of sagittal alignment. These were: a normal group, straight group, kyphosis group and hyper and hypolordosis groups. All volunteers underwent cervical spine CBCT scans at 7 functional positions. The range-of-motion (ROM) of each vertebra and the overall cervical spine were measured using a 3D-3D registration technique.
Results: In comparison to the normal group, the ROM of C3-C4 during left-right twisting in the kyphotic group was significantly higher, while the ROM of C1-C2 during left-right bending was also significantly greater. In addition, the ROM of C5-C6 in the straight group was higher during left-right bending in comparison to the normal group. During flexion-extension, the ROM of C4-C5 in kyphotic subjects was significantly lower than in the normal group, while in the C5-C6 segment, the ROM of the straight and the kyphotic groups was significantly greater compared to the normal group. During left-right bending, the global ROM of kyphotic subjects was higher than in the normal group.
Conclusions: 3D kinematics was used to accurately quantify the ROM of cervical spine under different curvatures under physiological load. The data implied that cervical kyphosis may have a greater impact on ROM. Our findings may contribute to prevent cervical spondylosis by early intervention in curvature changes.
Nemabiome metabarcoding shows a high prevalence of Haemonchus contortus and 1 predominance of Camelostrongylus mentulatus in alpaca herds in the northern UK
Authors: Zahid Osama , Butler Meghan , Hopker Andy , Freeman Emily , Júnior Livio M. Costa , Chaudhry Umer , Sargison Neil 
Published: July 2023

Abstract

Gastrointestinal nematodes (GINs) are a common threat faced by pastoral livestock. Since their major introduction to the UK in the early 1990s, South American camelids have been co-grazed with sheep, horses, and other livestock, allowing exposure to a range of GIN species. However, there have been no molecular-based studies to investigate the GIN populations present in these camelids. In the current study, we sampled nine alpaca herds from northern England and southern Scotland and used high-throughput metabarcoded sequencing to study the GIN species. A total of eight known GIN species were found, and 71 amplicon sequence variants (ASVs) were identified. Haemonchus contortus was the most prevalent species found in almost all herds in significant proportions. The identification of H. contortus in other livestock species is unusual in the area, implying that alpacas may be suitable hosts and potential reservoirs for infection in other hosts. In addition, the camelid-adapted GIN species Camelostrongylus mentulatus was identified predominantly on farms with higher faecal egg counts. These findings highlight the importance of applying advanced molecular methods, such as nemabiome metabarcoding to describe the dynamics of gastrointestinal nematode infections in novel situations. The results provide a strong base for further studies involving co-grazing animals to confirm the potential role of alpacas in transmitting GIN species between hosts.
Psychological intervention in parents of children with neurodevelopmental disorders using a brief protocol based on Acceptance and Commitment Therapy
Authors: Lobato David , Montesinos Francisco , Polín Eduardo , Flujas-Contreras Juan Miguel , Becerra Inmaculada Gómez , Budziszewska Lidia 
Published: July 2023

Abstract
Parenting children with neurodevelopmental disorders (NDDs) is associated with higher stress. The emotional coping of parents affects the psychological health of the whole family. 43 parents with children with NDDs and intellectual disabilities participated in two successive studies. A brief psychological intervention in group format based on Acceptance and Commitment Therapy (ACT) was administered. The intervention protocol is described in detail so that it can be used by other therapists. Standardized questionnaires were used to measure parental psychological flexibility, parental stress, thought suppression, and general health status, as well as behavioral self-monitoring of interactions with children for the analysis of family dynamics. The intervention was followed by sustained decreases in both psychological inflexibility and private events suppression and increases in general health. Parental stress was reduced at follow-up. There was a sustained increase in supportive interactions and a decrease in punitive interactions. A significant relationship was found between the level of previous psychological inflexibility and the magnitude of clinical change. The study provides evidence that ACT is particularly useful in coping with stress for parents with higher psychological inflexibility.
“All women in their 40s are miserable” - health care provision throughout the menopause in the UK: a mixed-methods study
Authors: Martin-Key Nayra , Funnell Erin L. , Spadaro Benedetta , Bahn Sabine 
Published: July 2023

Abstract
Background: The UK healthcare system faces a shortage of high-quality menopausal care.
Objective: To understand perspectives regarding the availability and quality of menopause care services in the UK.
Methods: An online survey was generated using Qualtrics XM®. Data from 952 respondents were analysed using a mixed-methods approach.
Results: 74.47% of women sought help for the menopause. Oral (68.83%) and topical medication (17.21%), as well as lifestyle changes (17.21%) were the most common treatment approaches. There was a lack of consistent integration of mental health screening into menopausal care. Open-ended response data from women who reported poor quality of care revealed six themes: consequences of poor care, dismissive or negative attitudes from healthcare professionals (HCPs), poor treatment management, symptom information and misattribution, poor HCP knowledge, and the need for self-advocacy.
Conclusions: The findings underscore the importance of improving HCP knowledge, providing empathetic and supportive care, and involving women in decision-making.