bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spin-orbit coupling effects on transmission and absorption of electromagnetic waves in gapped graphene armchair nanoribbon
Authors: Rezania H. , Abdi A 
Published: August 2023

Abstract
We compute the optical absorption, density of states and optical coefficients of graphene armchair nanoribbon under spin-orbit coupling effects. Kane-Mele model Hamiltonian has been applied for obtaining electronic band structure of graphene armchair nanoribbon in the presence of magnetic field and gap parameter. The effects of magnetic field and spin-orbit coupling strength on the frequency behavior of optical absorption of graphene armchair nanoribbon have been investigated. Also the frequency behavior of optical absorption of gapped graphene armchair nanoribbon has been studied due to magnetic field, spin-orbit coupling and gap parameter. Linear response theory and Green’s function approach have been exploited to obtain the frequency behavior of optical behavior of the structure. Moreover, the transmissivity and reflectivity of electromagnetic wave between two media separated by a graphene armchair nanoribbon are given. Our numerical results indicate that the frequency dependence of optical absorption includes a peak due to applying magnetic field. Also the frequency dependence of transmissivity and reflectivity of electromagnetic wave between two media separated by graphene armchair nanoribbon for normal incidence has been investigated due to effects of magnetic fields and spin-orbit coupling.
Comparision of Romberg and Fixed Tolerance Gaussian Quadrature Over Imaginary Exponent Functions
Authors: Kumar Tanmay 
Published: August 2023

Abstract
This research paper presents an extensive comparative investigation of two numerical integration techniques: Romberg1and Fixed Tolerance Gaussian quadrature,2 when applied to functions with Imaginary exponents. The main objective is to evaluate the accuracy and efficiency of these methods in approximating definite integrals over functions with imaginary powers. The study involves systematic analyses of the computational requirements and precision achieved by each method over multiple intervals. QUADPACK's3 adaptive quadrature is utilized as a benchmark. Through this study, valuable insights are offered into the performance of these quadrature techniques when dealing with integrals involving Imaginary exponents.
Letrozole Plus Misoprostol versus Misoprostol Alone in Induction of Anembryonic Missed Abortion: A Randomized Controlled Trial
Authors: Zekry Ramy Heshmat , Fouda Usama , Zaki Sherif Sameh , abdalla marwa 
Published: August 2023

Abstract
Background: letrozole is a third-generation aromatase inhibitor approved for breast cancer therapy. According to many recent studies, letrozole given for three days before the administration of misoprostol was more effective than misoprostol alone at inducing abortion. Our study compared the efficacy of various letrozole regimens (10 mg/d for three days and a single dose of 20 mg) combined with misoprostol vs. misoprostol alone in inducing abortion.
Methodology: Using a computer-generated randomization list and sequentially numbered sealed envelopes, we randomly divided 96 patients with anembryonic missed abortions into three equal groups (a single-dose letrozole group, a multiple-dose letrozole group, and a misoprostol-only group). Age, BMI, gestational age according to LMP, complete abortion rate, incomplete abortion rate, missed abortion rate, and induction-to-abortion interval were all collected.
Results: The complete abortion rate was significantly higher in the single-dose letrozole and the multiple-dose letrozole groups than in the misoprostol group (p-values = 0.0455 and 0.001, respectively). On the other hand, there was no significant difference in the complete abortion rate between the single-dose group and the multiple-dose letrozole group (p-value = 0.1713).
The time to complete abortion was significantly shorter in the single-dose and multiple-dose letrozole groups than in the misoprostol group (p-values = 0.0036 and 0.0049, respectively). On the other hand, there was no significant difference in the time to complete abortion between the single-dose letrozole group and the multiple-dose letrozole group (P = 0.532).
Conclusion: Single- and multiple-dose letrozole regimens followed by misoprostol had a higher rate and a shorter time to complete abortion than misoprostol alone. Administering a single-dose regimen of letrozole has the benefit of being more convenient and may improve patient compliance, but for its universal use, there is a need for more randomized controlled trials.
Trial registration: The trial is registered at gov with the name " Letrozole and abortion" and the identifier " NCT05198050." The date of registration was April 1, 2022, registered prospectively. URL: https://register.clinicaltrials.gov/prs/app/action/ViewOrUnrelease?uid=U0004GED&ts=25&sid=S000BPDQ&cx=43mobl
Environmental influence on feeding and biodeposition rates of Pacific oysters (Crassostrea gigas) throughout its culture cycle in a coastal lagoon with upwelling influence
Authors: Samperio_Ramos Guillermo Alberto , Vidal-Nieves Carlo , García-Esqu ZaúL , Herzka Sharon Z , Gil José Miguel Sandoval , Camacho-Ibar Víctor Froylan 
Published: August 2023

Abstract

Suspended oysters employ physiological strategies to adjust their metabolic needs with the available food resources. Using the biodeposition method, the feeding and processing behavior of Pacific oysters (Crassostrea gigas) was investigated with a field study comparing four periods (May, July, October, and December 2016) with different upwelling intensities in the coastal lagoon of San Quintin Bay (Mexico). We calculated physiological feeding responses throughout the culture cycle, including the clearance rate, filtration rate (FR), net organic ingestion rate (NOIR), net organic absorption rate (NOAR), net organic selection efficiency, and net absorption efficiency, as well as the ammonium excretion rate (AER). The dietary quality predictors showed large fluctuations in terms of total particulate material, organic fraction of seston, and chlorophyll concentration. Unlike the pumping activity, FR, NOIR, and NOAR were related to upwelling conditions, and C. gigas removed 2-fold, ingested 4-fold, and assimilated 5-fold more of the organic suspended material during the upwelling season compared with periods of weak upwelling. C. gigas showed the potential of depositing nearly twice the organic biodeposits to the sediments during intense upwelling. The highest AER was recorded in July and October, suggesting that seasonal temperature variation is the most important exogenous factor regulating nitrogen metabolism. Also, mechanistic models incorporating dietary quality predictors to the feeding and processing response functions of C. gigas were performed. We conclude that coastal upwelling plays an important bottom-up control on oysters’ feeding and processing activity, and our results facilitate further studies of the carrying capacity of embayments influenced by eastern boundary current systems.
Aqueous extract of CAP-ash: An innovative approach for Suzuki-Miyaura coupling reaction in palladium catalyzed ligand-free condition
Authors: Patil Rupesh C. , Patil Suresh S. 
Published: August 2023

AbstractA green and highly efficient Pd(OAc)2catalyzed Suzuki-Miyaura (SM) coupling reaction using an aqueous extract of CAP-ash (AECAP) at ambient temperature is reported to synthesize a variety of biphenyls. The analytical reports showed the presence of oxides which are probably extracted in water produces corresponding hydroxides, which provide alkaline media in water as a dual performance (solvent and base) for said cross-coupling transformation. The catalytic system is generated in situ based on aqueous extract and Pd(OAc)2which requires no external base and ligand. The custard apple peels were found to be natural agro-waste, highly cost-effective, operationally convenient, and easily recyclable.
Mid-to-late Holocene climate variability in coastal East Asia and its impact on ancient Korean societies
Authors: Park Jungjae , Bhak Junbeom , Park Jinheum , Kim Hyejin , Choi Jieun 
Published: August 2023

Abstract
The sustainability of human societies is contingent upon our ability to accurately predict the effects of future climate change on the global environment and humanity. Wise responses to forthcoming environmental alterations require extensive knowledge from historical precedents. However, in coastal East Asia, a region with a long history of agriculture, it is challenging to obtain paleoenvironmental proxy data without anthropogenic disturbances that can be used to assess the impact of late Holocene climate change on local communities. This study introduces a high-resolution multi-proxy sedimentary record from an isolated crater in Jeju Island, Korea, to elucidate the mechanisms underlying mid-to-late Holocene climate change and its impacts on ancient societies. Our findings suggest that hydroclimate changes were predominantly governed by sea surface temperature fluctuations in the western tropical Pacific, with low-frequency variability in solar activity and a decrease in summer insolation identified as primary drivers of temperature change. Moreover, ancient societies on the Korean peninsula were significantly affected by recurring cooling events, including the 2.8 ka event, 2.3 ka event, Late Antique Little Ice Age, maunder minimum, and others.
The Histomorphological and Stereological Assessment of Rat Dorsal Root Ganglion Tissues After Various Types of Sciatic Nerve Injury
Authors: Delibaş Burcu , KAPLAN Süleyman 
Published: August 2023

Abstract
Peripheral nerve injuries lead to significant changes in the dorsal root ganglia, where the cell bodies of the damaged axons are located. The sensory neurons and the surrounding satellite cells rearrange the composition of the intracellular organelles to enhance their plasticity for adaptation to changing conditions and responding to injury. Meanwhile, satellite cells acquire phagocytic properties and work with macrophages to eliminate degenerated neurons. These structural and functional changes are not identical in all injury types. Understanding the cellular response, which varies according to the type of injury involved, is essential in determining the optimal method of treatment. In this research, we investigated the numerical and morphological changes in primary sensory neurons and satellite cells in the dorsal root ganglion 30 days following chronic compression, crush and transection injuries using stereology, high-resolution light microscopy, immunohistochemistry, and behavioral analysis techniques. Electron microscopic methods were employed to evaluate fine structural alterations in cells. Stereological evaluations revealed no statistically significant difference in terms of mean sensory neuron numbers (p > 0.05), although a significant decrease was observed in sensory neuron volumes in the transection and crush injury groups (p < 0.05). Active caspase-3 immunopositivity increased in the injury groups compared to the sham group (p < 0.05). While crush injury led to desensitization, chronic compression injury caused thermal hyperalgesia. Electromyography parameters exhibited a significant decrease in the compression and crush injury groups compared to the sham group (p < 0.05). Macrophage infiltrations were observed in all injury types. Electron microscopic results revealed that the chromatolysis response was triggered in the sensory neuron bodies from the transection injury group. An increase in organelle density was observed in the perikaryon of sensory neurons after crush-type injury. This indicates the presence of a more active regeneration process in crush-type injury than in other types. The effect of chronic compression injury is more devastating than that of crush-type injury, and the edema caused by compression significantly inhibits the regeneration process.
Machine learning-based hub gene identification of pyroptosis-related nonalcoholic fatty liver disease
Authors: yang luping , Liu Shiyi , Zhou Run , Shi Junping 
Published: August 2023

Abstract
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive lipid deposition and metabolic imbalance in hepatocytes, which may lead to the occurrence and development of a variety of diseases (various chronic liver diseases, cirrhosis, etc.). Pyroptosis is a programmed cell death, and its role in NAFLD remains unclear. This paper aimed to explore the hub genes and involved biological processes related to NAFLD diagnosis and pyroptosis by machine learning methods and further analyze the differences in immune infiltration between healthy obesity and NAFLD from the perspective of transcriptome data. The results showed that IL32, TREM2 and PANX1 were potentially closely related to NAFLD by random forest algorithm. We verified the diagnostic performance of the three genes in the internal and external test sets, respectively. T Its AUC in the internal test set reached 0.850, and the AUC in the external test set reached 0.803. In addition, the correlation between three genes and immune cells was analyzed in detail, and three genes were found to evaluate the immune microenvironment of patients. This study provided a basis for revealing the molecular mechanism associated with NAFLD.
From disease to people-centred pandemic management: organized communities, community oriented primary care and health information systems
Authors: Leyns Christine , Willems Sara , Powell Richard A. , Camacho Vivian , Fabrega Ricardo , De Maeseneer Jan , Rawaf Salman , Mangtani Punam , El-Osta Austen 
Published: August 2023

Abstract
Background
The COVID-19 pandemic exposed the health equity gap within and between countries. Western countries were the first to receive vaccines and mortality was higher among socially deprived, minority and indigenous populations within countries. Surprisingly, many sub-Saharan countries presented low excess mortalities. These countries share experience with community organization and participation in health. The aim is to analyse if and how this central role of people can promote a successful pandemic response.
Methods
This analysis is partly based on local and national experiences shared during an international and Latin American conference on person-and people-centred care in 2021. Additionally, excess mortality data and data relevant for pandemic control as well as literature on the pandemic response of countries with an unexpected low excess mortality were consulted.
Results
Togo, Mongolia, Thailand, and Kenya had a seven times lower mean excess mortality for 2020 and 2021 than the United States of America. More successful pandemic responses were seen in settings with experience in managing epidemics like Ebola and HIV, well-established community networks, a national philosophy of mutual aid, financial government assistance, more human resources for primary care and paid community health workers.
Discussion
Since trust in authorities and health needs vary greatly, local strategies are needed to complement national and international pandemic responses. Three key levers were identified to promote locally tailored pandemic management: (1) well-organized communities, (2) community-oriented primary care and (3) health information systems. An organized community structure stems from a shared ethical understanding of humanity as being interconnected with each other and the environment. This structure facilitates mutual aid and participation in decision making. Community-oriented primary care includes attention for collective community health and ways to improve health from its roots. A health information system supports collective health and health equity analysis by presenting health needs stratified for social deprivation, ethnicity, and community circumstances.
Conclusions
The difference in excess mortality between countries during the COVID-19 pandemic and various country experiences, demonstrate the potential of the levers in promoting a more just and effective health emergency response. These same levers and strategy can promote more inclusive and socially just health systems.
ACSL4 Inhibition Prevents Macrophage Ferroptosis and Alleviates Fibrosis in Bleomycin-induced Systemic Sclerosis Model
Authors: Cao Dianyu , Zheng Jina , Li Zheng , Yu Yong , Chen Zengrui , Wang Qiang 
Published: August 2023

Abstract
Background.
Systemic sclerosis (SSc), with unclear pathophysiology, is a paradigmatic rheumatic disease of immunity dysfunction driven multi-organ inflammation and ultimate fibrosis. Pathogenesis breakthroughs are urgently needed for available treatments halting its unremitting stiffness. This study aims to investigate whether ferroptosis can regulate the progressive SSc fibrosis.
Methods
In vivo, bleomycin (BLM) -induced mice model were subjected to ferroptosis detection using western blotting, malondialdehyde (MDA) and glutathione (GSH) assays. Pharmacological inhibitor of the acyl-CoA synthetase long-chain family member 4 (ACSL4) was utilized to explore its potential therapeutic effects for fibrosis, from histological, biochemical, proteomic and molecular analyses. In vitro, bone marrow-derived macrophages (BMDM) was activated into inflammatory phenotype and then evaluated the relationship between activation level and ferroptosis sensitivity in lipopolysaccharide(LPS)incubation with gradient concentration. The potential calpain/ACSL4 axis was analyzed after calpain knockdown or over-expression in Raw264.7.
Results.
A wild rage of tissue ferroptosis was present in SSc mice with enhanced ACSL4 expression, while ACSL4 inhibition effectively halted fibrosis progressing and provides protection from inflammatory milieu. Meanwhile, a positive regulation relationship between LPS-induced macrophage activity and ferroptosis sensitivity can be observed. After calpain knockdown, both inflammatory macrophage ferroptosis sensitivity and ACSL4 expression decreased, while its over-expression renders ACSL4-envoking condition. Also, calpain pharmacological inhibition reduced both ferroptosis and fibrosis aptitude in mice.
Conclusions.
ACSL4 induces inflammatory macrophage ferroptosis to aggravate fibrosis progressing. ACSL4 and its up-regulators of calpains may be potential therapeutic targets for BLM model of SSc.
Obsolete Solar Panels Recycling and Economic Growth
Authors: Vita Giuseppe Di 
Published: August 2023

Abstract
In this paper we investigate the impact of obsolete solar panels recycling on the economic growth rate and the optimal time of depletion of exhaustible resource. Using a simple growth model where the solar panels constitutes the physical capital, the labor and exhaustible resource, we study how the recycling of obsolete solar panels impacts the growth rate and the optimal exhaustion time of this kind of natural input. The optimal switching point of time is derived, from the regime where primary and secondary input are used together, to the regime in which the exhaustible resource is completely depleted and only secondary material is used.
JEL classification: O44; Q32.
Genomic Characterization of Transgenic Wheat (Triticum Aestivum L.) Using Fluorescence IN SITU Hybridization
Authors: Auteri Micol , Nieves Mariela , Fradkin Maia , Giardini María Cecilia , Faccio Paula , Beznec Ailin , Bossio Ezequiel 
Published: August 2023

Abstract
Fluorescence in situ hybridization (FISH) is a powerful tool to visualize specific DNA fragments in cultured cells, tissue sections or whole-mount preparations. The cytogenetic slides that serve as a target for the labeled DNA probe might be prepared using any approach suitable for obtaining cells with appropriate morphology for imaging and analysis. In mitotic metaphases, this technique allows to detect the presence of chromosomes and/or introgressive chromosomal segments. This study was conducted to identify the transgene copy number by FISH in transgenic wheat (Triticum aestivum L.) lines previously obtained and compared the accuracy of this methodology to the traditional Southern blot technique. We obtain chromosomal preparations and evaluated mitotic metaphases testing four FISH protocols on a set of two transgenic wheat lines. A total of 24 experiments (three experiments for two transgenes in each transgenic line, and the control line) were conducted. FISH analyses of individual transgenic events revealed multiple insertions of transgene fragments. The results obtained in this work showed that FISH allows determining the number of the transgene insertions in the genome of transgenic wheat plants in an accurate way and emerges as a viable alternative to replace the traditional technique of hybridization, Southern Blot.
A piecewise thickness-function to the interferometric measurement of the optically transparent thin films
Authors: Gasca-Figueroa Davidd , García-Rodríguez Francisco J. , Castro-Beltrán Rigoberto , Perez-Pinal Francisco J. , Vélez-García Rogelio D. , Gutiérrez-Juárez Gerardo 
Published: August 2023

Abstract
A new piecewise thickness-function to determine the thickness of extremely transparent thin films, through the monochromatic-light-interferometric data, is proposed. The piecewise thickness-function is based on the gray values interference patterns, studied as a piecewise function as well. In the gray value piecewise function each subfunction corresponds to an interferometric branch, which is related to reflectivity from where a new rescaled gray value piecewise function is proposed to obtain the piecewise thickness function. The rescaled gray-values piecewise function is in the interval [0,1], which avoids divergences on the reflectivity function. The thickness function approach was tested by obtaining the meniscus thickness of a water droplet. We got an adsorbed layer thickness of \(21\pm 2.2 \text{n}\text{m}\). In addition, we demonstrated numerically that our proposal includes or improves other methods previously reported. The process was validated in two ways, i) numerical simulation and ii) comparison with previous works. Finally, the application of our data analysis procedure to obtain dynamic meniscus thickness in real-time is discussed.
Release of soybean (Glycine max L.) polyphenols by solid-state fermentation with Eurotium cristatum and its effect on glycemic index
Authors: Shi Shuo-shuo , Hu Ting 
Published: August 2023

Abstract
In this study, soybean (Glycine max L.) by using solid-state fermentation (SSF) technology and was fermented by Eurotium cristatum. The influence of SSF on the composition of free polyphenols (FP), bound polyphenols (BP), total polyphenols (TP) and FP in soybean before and after fermentation was investigated. The results showed that the content of FP and TP increased significantly during SSF process. After 12 days of SSF, FP, BP and TP in soybean were approximately 3.98-, 1.38-, 3.16 higher, respectively. HPLC-MS/MS analysis detected 10 kinds of substances were newly formed in the FP during SSF process. Furthermore, SSF with E. cristatum considerably scaveng effects against ABTS·+ and DPPH radical, reducing power, and chelating ability of soybeans, and its hypoglycemic activity was significantly enhanced. And the FP of soybeans after fermentation can reduce the glycemic index (GI) of common foods. This research demonstrated that solid-state bioprocessing with E. cristatum is an effective way to increase polyphenols content and hypoglycemic ability of soybeans. Compared with unfermented soybean, fermented soybean products might have great potential in hypoglycemic agents or be used as a new natural source applied in hypoglycemic.