bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanomaterials for hyperpolarized nuclear magnetic resonance and magnetic resonance imaging
Authors: Saul Philip , Schröder Leif , Schmidt Andreas B. , Hövener Jan‐Bernd 
Published: February 2023

AbstractNanomaterials play an important role in the development and application of hyperpolarized materials for magnetic resonance imaging (MRI). In this context they can not only act as hyperpolarized materials which are directly imaged but also play a role as carriers for hyperpolarized gases and catalysts for para‐hydrogen induced polarization (PHIP) to generate hyperpolarized substrates for metabolic imaging. Those three application possibilities are discussed, focusing on carbon‐based materials for the directly imaged particles. An overview over recent developments in all three fields is given, including the early developments in each field as well as important steps towards applications in MRI, such as making the initially developed methods more biocompatible and first imaging experiments with spatial resolution in either phantoms or in vivo studies. Focusing on the important features nanomaterials need to display to be applicable in the MRI context, a wide range of different approaches to that extent is covered, giving the reader a general idea of different possibilities as well as recent developments in those different fields of hyperpolarized magnetic resonance.This article is categorized under:
Therapeutic Approaches and Drug Discovery > Emerging Technologies
Diagnostic Tools > In Vivo Nanodiagnostics and Imaging
Research on the Integration Technology of Structural Performance Evaluation and 3D Design for Spatial Steel Structure Bridges
Authors: Zhu Kewei , Li Bing 
Published: February 2023

AbstractWith the increase of steel structure bridges, the design of steel structure bridges begin to evolve in the direction of high quality, high precision, and short design period. In order to improve the design quality and efficiency of spatial steel structure bridges, the integration technology of structural performance evaluation and 3D design of spatial steel structure bridges is studied. Firstly, the 3D design is carried out based on the rapid design method, and then the finite element simulation is conducted by software to analyze its structural performance and optimize the 3D design model. The research results link the rapid design and structural analysis software systematically, so as to realize the integrated design of spatial irregular bridge components with BIM and FEM technology.
Study on the Properties of Concrete with Different Admixtures in Acid Corrosive Environment
Authors: Yu Lei , Zhao Tianyuan , Wang Zhi 
Published: February 2023

AbstractTo study the deteriorating law and find a proper admixture to enhance the durability of the concrete in the acid corrosion environment, the corrosion and deterioration of concrete with different types and proportions of admixtures were studied. The appearance morphology, strength, chloride penetration depth, and porosity of ordinary concrete and concrete with different types of admixtures under water curing and corrosion solution erosion were compared. The results show that in terms of improving the corrosion resistance of concrete, the single-mixed mineral powder shows excellent performance. The addition of fly ash significantly increases the content of 10–100 nm pores, and the strength is low at an early age, but the strong growth is limited at the later stage.
Analysis on Reinforcement of Statically Indeterminate Truss
Authors: Liang Ziyi , Wei Mingjun , Yu Long 
Published: February 2023

AbstractWith the slowdown of the urbanization rate and new buildings in China, the old houses have different degrees of safety problems. Therefore, the importance of reinforcement and reconstruction of old houses has become increasingly apparent. This paper intends to study statically indeterminate trusses in buildings. Based on the finite element analysis, the paper compares the influence of the method of increasing section area on the original truss structure by establishing the reconstruction scheme of the same statically indeterminate truss. The numerical simulation results show that the ultimate bearing capacity of the structure is increased to achieve the purpose of strengthening.
Aseismic Design of an Out-of-Code High-Rise Building in Shanghai
Authors: Ren Hongmei , Zhu Jianping , Lv Yanyan , Qin Weiwei 
Published: February 2023

AbstractProper structural system and performance-based seismic design are the key issues in designing high-rise building structures. This project has unique building facade shape and complex plane function layout, and the structural plane and vertical layout are irregular. The superstructure adopts assembled integral concrete frame-shear wall structure, which is judged as out-of-code high-rise building by seismic review. Firstly, the site conditions, foundation design and structural form selection are introduced. Then, YJK software is used to calculate and analyze the seismic force of the superstructure, and the seismic performance indexes of the structure can meet the requirements of the code. Finally, the regularity of each structural unit of the superstructure is judged, and the corresponding main seismic strengthening measures are put forward.
Analysis on Migration Mechanism of Chloride Ions in Concrete Close-End Pipe Piles
Authors: Yang Bo. 
Published: February 2023

AbstractDifferent migration mechanisms of chloride in concrete are introduced and various kinds of influences on diffusion coefficient, including temperature, relative humidity and age are also elaborated. Based on Fick second law and the boundary condition of close-end pipe pile, the analytical solution to chloride migration equation due to the process of both diffusion and convection is deduced. Applying this result to a typical jacked PHC pile, the chloride concentration is analyzed and the effect, which the seepage velocity, thickness of pipe pile and the diffusion coefficient have on distribution of chloride concentration, is also discussed. This example provides a computational basis for the corrosion of steel bar and some reference values for durability design of pipe pile.
Numerical Simulation Research for Rock Stability of Ventilation and Safety Tunnel of Karuma Hydropower Plant
Authors: Li Hua , Liu An , Shi Ting , Niu Meifeng 
Published: February 2023

AbstractAccording to the latest physical mechanical parameter of rock, crustal stress, section style and support parameter, rock stability of intersection of EVT- Ventilation Tunnel 2-1 and Ventilation Shaft 2 is analyzed and verified through FLAC3D on the base of actual geology parameter and test value of crustal stress.
The External Prestress Effect of Curved Tendons on the Natural Vibration Characteristics of Steel Beams
Authors: Xu Zhi-wei , Lin Li-xia , Ding Nan-hong , Chen Lei 
Published: February 2023

AbstractIn order to explore the external prestress effect of the curved tendons on the stiffness and natural vibration characteristics of the steel beam, this paper deduced the calculation equation of the natural frequency on the external prestressed simply supported steel beam of the curved arrangement, which was based on the Hamilton principle. The natural frequency is calculated by combining the example of I-shaped simply supported steel beam, which was analyzed and verified by establishing the finite element model. The results show that: the calculation of the equation is well demonstrated by the finite element results, and the validity of model equation was verified. When the applied prestress increases, the natural vibration frequency decreases and the change range is not large, which indicates that the magnitude of the prestress has little effect on the natural frequency of simply supported steel beams.
Research on Damage Mechanism and Structural Optimization of Joints in Cavity Shear Wall Structure
Authors: Tian Yong , Shi Guanghui , Zhang Bo , Guo Kun , Luo Fajiang , Chen Shengjie , Bai Yibo 
Published: February 2023

AbstractAfter pouring concrete precast cavity shell structure has been developing rapidly in recent years, compared with cast-in-place structure, the new fabricated structure has low cost, high construction efficiency, and the advantages of green environmental protection, the shear wall structure is most widely used, which includes the prefabricated plate shell, annular tendon layout, cast-in-situ construction important process. But by several times with the stress of the casting of concrete and the overall disposable pouring forms have obvious differences, including the layered interface, the material interface, the cross section of damage caused by the stiffness degradation, and eventually results in the decrease of carrying capacity. In this paper, the damage mechanism of precast shear wall with cavity is analyzed, and the optimization method of connecting parts is studied and discussed.
Research on Restoring Force Model of Built-in Steel Tube Reinforced STRC Column Joints
Authors: Zhang Jiahao , Wang Qiuwei 
Published: February 2023

AbstractIn the circular steel tube confined reinforced concrete (STRC) column frame structure, because there is no effective restraint of steel tube in the joints area, it becomes a relatively weak part. Therefore, this paper proposes a STRC column joints with a section of steel tube built in the joints area, and expounds the structural form of the new joints. ABAQUS finite element analysis software is used to simulate the quasi-static test of joints. On the basis of verifying the rationality and reliability of the finite element analysis method, six joints models of build-in steel tube reinforced STRC columns with different lengths are established. Based on the model skeleton curve obtained by simulation analysis, the eigenvalues of each loading stage are fitted to obtain the skeleton curve model regression equation and stiffness degradation law. The three fold restoring force model of steel tube STRC column joints with different lengths is established. The skeleton curves of restoring force model and finite element calculation results are compared and analyzed to verify the correctness of restoring force model. The results show that the restoring force model is in good agreement with the finite element analysis results. The established restoring force model can provide a reference for the elastic-plastic change and seismic analysis of build-in steel tube reinforced STRC column joints.
One-loop amplitudes in Einstein-Yang-Mills from forward limits
Authors: Porkert Franziska , Schlotterer Oliver 
Published: February 2023

Abstract
We present a method to compute the integrands of one-loop Einstein-Yang-Mills amplitudes for any number of external gauge and gravity multiplets. Our construction relies on the double-copy structure of Einstein-Yang-Mills as (super-)Yang-Mills with the so-called YM+ϕ3 theory — pure Yang-Mills coupled to bi-adjoint scalars — which we implement via one-loop Cachazo-He-Yuan formulae. The YM+ϕ3 building blocks are obtained from forward limits of tree-level input in external gluons and scalars, and we give the composition rules for any number of traces and orders in the couplings g and κ. On the one hand, we spell out supersymmetry- and dimension-agnostic relations that reduce loop integrands of Einstein-Yang-Mills to those of pure gauge theories. On the other hand, we present four-point results for maximal and half-maximal supersymmetry where all supersymmetry cancellations are exposed. In the half-maximal case, we determine six-dimensional anomalies due to chiral hypermultiplets in the loop.
On interim performance evaluations and interdependent period outcomes
Authors: Lukas Christian 
Published: February 2023

AbstractPerformance feedback is an integral element of an accounting system, and firms provide this feedback at varying frequencies to their employees. This paper explicates the impact of an interim performance evaluation on the principal’s surplus using a dynamic two-period agency model. Two settings are discussed: single-purpose use, wherein accounting information is used solely for control purposes, and dual-purpose use, in which accounting information is used for production and control. Results demonstrate that the optimality of interim performance evaluations depends on the use of information and the interdependence of period outcomes. Furthermore, neither setting entails strict dominance with regard to carrying out interim evaluations or not. It implies that an interim evaluation can be optimal even if the optimal course of action does not depend on it. It further suggests that refraining from the interim review can be optimal even if that information is required to determine the optimal effort level.
The prognostic value of CZT SPECT myocardial blood flow (MBF) quantification in patients with ischemia and no obstructive coronary artery disease (INOCA): a pilot study
Authors: Zhang Han , Caobelli Federico , Che Wenliang , Huang Yan , Zhang Yu , Fan Xin , Hu Xueping , Xu Chong , Fei Mengyu , Zhang Jiajia , Lv Zhongwei , Shi Kuangyu , Yu Fei 
Published: February 2023

Abstract
Background
Despite the demonstrated adverse outcome, it is difficult to early identify the risks for patients with ischemia and no obstructive coronary artery disease (INOCA). We aimed to explore the prognostic potential of CZT SPECT in INOCA patients.

Methods
The study population consisted of a retrospective cohort of 118 INOCA patients, all of whom underwent CZT SPECT imaging and invasive coronary angiography (ICA). Dynamic data were reconstructed, and MBF was quantified using net retention model. Major adverse cardiovascular events (MACEs) were defined as cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, heart failure, late coronary revascularization, or hospitalization for unstable angina.

Results
During a median follow-up of 15 months (interquartile range (IQR) 11–20), 19 (16.1%) MACEs occurred; both stress myocardial blood flow (sMBF) ($$p<0.001$$

p
<
0.001

) and coronary flow reserve (CFR) ($$p<0.001$$

p
<
0.001

) were significantly lower in the MACE group. Optimal thresholds of sMBF<3.16 and CFR<2.52 were extracted from the ROC curves, and both impaired sMBF (HR: 15.08; 95% CI 2.95–77.07; $$p=0.001$$

p
=
0.001

) and CFR (HR: 6.51; 95% CI 1.43–29.65; $$p=0.01$$

p
=
0.01

) were identified as prognostic factors for MACEs. Only sMBF<3.16 (HR: 11.20; 95% CI 2.04–61.41; $$p=0.005$$

p
=
0.005

) remained a robust predictor when sMBF and CFR were integrated considered. Compared with CFR, sMBF provides better prognostic model discrimination and reclassification ability (C-index improvement = 0.06, $$p=0.02$$

p
=
0.02

; net reclassification improvement (NRI) = 0.19; integrated discrimination improvement (IDI) = 0.10).

Conclusion
The preliminary results demonstrated that quantitative analysis on CZT SPECT provides prognostic value for INOCA patients, which may allow the stratification for early prevention and intervention.
Trismus, health-related quality of life, and trismus-related symptoms up to 5 years post-radiotherapy for head and neck cancer treated between 2007 and 2012
Authors: Aghajanzadeh Susan , Karlsson Therese , Tuomi Lisa , Engström My , Finizia Caterina 
Published: February 2023

Abstract
Purpose
Radiotherapy-induced trismus is present in up to 40% of patients treated radiotherapeutically for head and neck cancer (HNC) and impacts health-related quality of life (HRQL) negatively. This prospective study aimed to investigate the development of trismus and its influence on HRQL and trismus-related symptoms in HNC patients for up to 5 years post-radiotherapy completion as no such follow-up studies exist.

Methods
Patients (n = 211) were followed prospectively from pre-radiotherapy to 12 and 60 months post-radiotherapy. At each follow-up, maximum interincisal opening (MIO) was measured, and patients filled in the European Organization for Treatment of Cancer Quality-of-Life Questionnaire Core-30 (EORTC QLQ-C30), Head and Neck-35 (EORTC QLQ-HN35), and Gothenburg Trismus Questionnaire (GTQ). Trismus was defined as an MIO ≤ 35 mm.

Results
At 1 year post-radiotherapy, a total of 27% met the trismus criterion, and at 5 years post-radiotherapy, the corresponding figure was 28%. Patients in the trismus group scored significantly worse compared to the patients without trismus on 8/15 domains at 1 year post-radiotherapy on EORTC QLQ-C30, further worsening in 11/15 domains at 5 years post-radiotherapy. Similar results were found for EORTC QLQ-HN35. Patients with trismus reported more trismus-related symptoms according to the GTQ at both timepoints compared to those without trismus.

Conclusion
This study highlights that HNC patients suffering from radiotherapy-induced trismus report poorer HRQL and more trismus-specific symptoms compared to patients without trismus. These differences persist and increase up to at least 5 years following treatment completion. Hence, our results highlight that radiotherapy-induced trismus affects long-term HRQL, jaw symptoms, and pain, further stressing the need for early and structured intervention.
Long-term effects of chronic stress models in adult mice
Authors: Tran Inès , Gellner Anne-Kathrin 
Published: February 2023

AbstractNeuropsychiatric disorders, such as major depression, anxiety disorders, and post-traumatic stress disorder, tend to be long-term conditions in whose development and maintenance stress are central pathogenic factors. Translational mouse models are widely used in neuropsychiatric research, exploiting social and non-social stressors to investigate the mechanisms underlying their detrimental effects. However, most studies focus on the short-term consequences of chronic stress, whereas only a few are interested in the long-term course. This is counterintuitive given the human conditions that preclinical models are designed to mimic. In this review, we have summarized the limited work to date on long-term effects of chronic stress in mice models. First, the different models are presented and a definition of short- vs. long-term sequelae is proposed. On this basis, behavioral, endocrine, and vegetative effects are addressed before examining data on cellular and molecular alterations in the brain. Finally, future directions for research on the long-term effects of stress are discussed.
Anxiety and depression in keratotic oral lichen planus: a multicentric study from the SIPMO
Authors: Adamo Daniela , Calabria Elena , Canfora Federica , Coppola Noemi , Leuci Stefania , Mignogna Martina , Muzio Lorenzo Lo , Spirito Francesca , Giuliani Michele , Azzi Lorenzo , Dani Marta , Colella Giuseppe , Colella Chiara , Montebugnoli Lucio , Gissi Davide Bartolomeo , Gabriele Mario , Nisi Marco , Sardella Andrea , Lodi Giovanni , Varoni Elena Maria , Giudice Amerigo , Antonelli Alessandro , Gambino Alessio , Antonucci Giuliana , Vescovi Paolo , Meleti Marco , Majorana Alessandra , Bardellini Elena , Campisi Giuseppina , Panzarella Vera , Spadari Francesco , Garagiola Umberto , Pentenero Monica , Sutera Samuele , Biasotto Matteo , Ottaviani Giulia , Gobbo Margherita , Nardini Luca Guarda , Romeo Umberto , Tenore Gianluca , Serpico Rosario , Lucchese Alberta , Lajolo Carlo , Gioco Gioele , Aria Massimo , D’Aniello Luca , Mignogna Michele Davide ,   SIPMO (Italian Society of Oral Pathology, Medicine)
Published: February 2023

Abstract

Objectives
Oral lichen planus with exclusive keratotic reticular, papular, and/or plaque-like lesions (K-OLP) is a clinical pattern of OLP that may be associated with a complex symptomatology and psychological alteration. The aim of the study was to evaluate the prevalence of anxiety (A) and depression (D) in patients with K-OLP, analyzing the potential predictors which can affect mental health status.

Methods
Three hundred K-OLP patients versus 300 healthy controls (HC) were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), and Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A) were administered.

Results
The K-OLP patients showed statistically higher scores in the NRS, T-PRI, HAM-D, and HAM-A compared with the HC (p-value < 0.001**). A and D were found in 158 (52.7%) and 148 (49.3%) K-OLP patients. Strong linear correlations were identified between HAM-A, HAM-D, NRS, T-PRI, and employment status and between HAM-D, HAM-A, NRS, T-PRI, employment status, and female gender. Multivariate logistic regression revealed that HAM-D and HAM-A showed the greatest increase in the R2 value for A and D in the K-OLP patients, respectively (DR2 = 55.5% p-value < 0.001**; DR2 = 56.5% p-value < 0.001**).

Conclusions
The prevalence of A and D is higher in the K-OLP patients compared with the HC, also found in K-OLP subjects without pain, suggesting that the processing of pain may be in a certain way independent of the processing of mood.

Clinical relevance
Mood disorders and pain assessment should be carefully performed in relation to K-OLP to obtain a complete analysis of the patients.
Elastic similarity and distance measures for multivariate time series
Authors: Shifaz Ahmed , Pelletier Charlotte , Petitjean François , Webb Geoffrey I. 
Published: February 2023

AbstractThis paper contributes multivariate versions of seven commonly used elastic similarity and distance measures for time series data analytics. Elastic similarity and distance measures can compensate for misalignments in the time axis of time series data. We adapt two existing strategies used in a multivariate version of the well-known Dynamic Time Warping (DTW), namely, Independent and Dependent DTW, to these seven measures. While these measures can be applied to various time series analysis tasks, we demonstrate their utility on multivariate time series classification using the nearest neighbor classifier. On 23 well-known datasets, we demonstrate that each of the measures but one achieves the highest accuracy relative to others on at least one dataset, supporting the value of developing a suite of multivariate similarity and distance measures. We also demonstrate that there are datasets for which either the dependent versions of all measures are more accurate than their independent counterparts or vice versa. In addition, we also construct a nearest neighbor-based ensemble of the measures and show that it is competitive to other state-of-the-art single-strategy multivariate time series classifiers.