bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual Trigger in IVF—A SWOT Analysis
Authors: Manivasagam Aruna , Samanta Jayeeta , Mathur Raj 
Published: January 2025

The typical agent used for final oocyte maturation and resumption of meiosis in in-vitro fertilisation (IVF) has been human chorionic gonadotropin (hCG). This acts as a surrogate for the physiological spontaneous luteinising hormone (LH) surge. Gonadotropin-releasing hormone agonist (GnRH-a) has been used as an alternative trigger in cycles where endogenous LH control is achieved using GnRH-antagonist and has been shown to be an effective method of reducing the risk of OHSS. However, GnRHa trigger is associated with poor corpus luteum function, leading to impaired endometrial receptivity.
A combination of a GnRHa and hCG (dual trigger) was proposed to improve IVF cycle outcomes, especially in poor and normo-responder patients. Dual trigger aims to provide a more physiological alternative to HCG-only trigger while obviating some of the problems associated with GnRHa alone. Clinical evidence now supports the value of dual trigger where there has been a previous low proportion of mature eggs or where there is a suboptimal LH response to GnRHa alone. In poor responders, dual triggers could be considered as an effective first line. Dual trigger allows for comparable outcomes in normal and high responders, allowing the possibility of fresh embryo transfer with good clinical pregnancy and live birth rates while minimising OHSS risk.
ПОЧВЕННЫЕ ИССЛЕДОВАНИЯ В КОЛОНИЗАЦИОННЫХ ЭКСПЕДИЦИЯХ ПОД РУКОВОДСТВОМ К. Ф. МАЛЯРЕВСКОГО НА ТЕРРИТОРИИ АВТОНОМНОЙ ОБЛАСТИ КОМИ (1926-1929)
Authors: ЕГОРОВА С Л. , СУСЛОВА Н Г. 
Published: January 2025

В статье на основе документов Научного архива Коми НЦ УрО РАН и Национального архива Республики Коми представлены задачи, маршруты, условия работы, результаты обследований обширного Печорского края колонизационной экспедицией К.Ф. Маляревского (1926-1929), особое внимание уделено почвенным исследованиям.
Based on documents from the Scientific Archive of the Komi Science Centre of the Ural Branch of the Russian Academy of Sciences and the National Archive of the Komi Republic, the article presents the tasks, routes, working conditions, and results of surveys of the vast Pechora Region by the colonization expedition of K.F. Malyarevsky (1926-1929), with special attention paid to the soil studies.
Hand hygiene for prevention and control of viral infections: the role of Amuchina Gel Xgerm
Authors: Cermelli Claudio , Blasi Elisabetta , Capezzone de Joannon Alessandra , Roselli Maria Ilaria , Frollano Daniele , Procaccini Michela 
Published: January 2025

Introduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation.
Methods: In this study, viral suspensions composed by the test virus, an interfering substance, and the test product, were exposed to Amuchina Gel Xgerm (100 g of the product contains 74 g of ethanol 96%; Angelini Pharma S.p.A) at 80% dilution in water, according to the European Standard EN14476:2013+A2:2019 – quantitative suspension test for the evaluation of virucidal activity in the medical area – for chemical disinfectants and antiseptics, in the presence of bovine serum albumin 0.3 g/L. The residual viral titers were measured.
Results: Sixty second exposures to the product determined a ≥4 log10 reduction of virus titer in all cases. For adenovirus type 5, human coxsakievirus, herpesvirus 1 and influenza virus A H1N1, a ≥4 log10 reduction of virus titer was obtained already after 30 s. Amuchina Gel Xgerm demonstrated effectiveness against seven virus families, including both enveloped and non-enveloped viruses.
Conclusion: Amuchina Gel Xgerm is a preventive measure against infection spread in healthcare and community settings, contributing to improved healthcare management.
“I learned a lot about me as a person”: University students’ development as non-formal education professionals
Authors: Simpson Amber , McCann Jada , Murtaugh Diana , Miroff Laurie E. 
Published: January 2025

IntroductionThe role of non-formal educational professionals has implications for the growth and development of the children they interact with. This group of professionals includes university students who volunteer their time in educational and youth-service organizations.MethodsIn this collective case study, we utilized Cultural-Historical Activity Theory to (a) understand how undergraduate and graduate students negotiated their development as a non-formal educational professional within an afterschool program and (b) consider how contradictions influenced their growth as educators, if at all. Three forms of data were collected from 10 graduate and undergraduate students as they volunteered their time as an educator in a 10-week afterschool program in partnership with two rural middle schools.ResultsResults highlighted shared contradictions among university students, such as lack of content knowledge and being viewed as friend versus being viewed as an educator, as they individually and collectively reflected upon their development and growth as non-formal educators within the afterschool program. Results also underscored how being a part of the afterschool program and reflecting on practice supported only some of the university students’ initial goal(s) for volunteering their time.DiscussionWe conclude with implications of this study for universities to consider in supporting the professional growth and development of their students as active learners and future educational professionals.
Assessment of interocular symmetry of choroidal vascularity index and thickness in patients with systemic sclerosis: a prospective study
Authors: Raciborska Anna , Pieklarz Barbara , Gińdzieńska-Sieśkiewicz Ewa , Zonenberg Agnieszka , Kowal-Bielecka Otylia , Konopińska Joanna , Dmuchowska Diana A. 
Published: January 2025

PurposeSystemic sclerosis (SSc) affects blood vessels, internal organs, and skin. In ophthalmology, SSc impacts the choroid. The choroidal vascularity index (CVI) measures the vascular component of the choroid and may serve as a biomarker for the disease staging and prognosis. Studies have reported reduced choroidal thickness and altered CVI in SSc, which supports the theory of vascular damage. This study aimed to examine interocular symmetry in choroidal parameters among SSc patients. It has provided the insight into the disease symmetry and assessed the representativeness of examining one eye.MethodsThis prospective single-center cross-sectional study included 33 patients with SSc and 40 healthy controls. The patients underwent ophthalmological examination (including refraction, visual acuity, IOP, biometry, slit-lamp biomicroscopy, dilated fundus examination, and spectral-domain optical coherence tomography) and rheumatological evaluation. Various parameters of the choroid in the macular and peripapillary regions were analyzed, including choroidal thickness, choroidal volume, and CVI. The interocular asymmetry in the choroidal parameters was quantified using signed and absolute differences. The correlation analysis between the left and right eyes was based on the intraclass correlation coefficient (ICC), Spearman’s correlation coefficient, and paired Wilcoxon test.ResultsThere were no significant differences in the macular and peripapillary choroidal parameters between fellow eyes in both SSc patients and controls (p &gt; 0.05). The parameter that showed the lowest correlation among those examined was CVI—in both groups, as well as in both examined areas. The interocular correlation of choroidal parameters was stronger in the peripapillary area than in the macular area in both groups. In general, the results were confirmed in subgroup analyses stratified according to sex, SSc subtype, Scl70 antibody positivity and previous and/or active digital ulcers.ConclusionThere is interocular symmetry of the choroidal parameters in patients with SSc and controls included in our study. The parameters from one eye are representative of the fellow eye of a given patient. This conclusion may contribute to the design and interpretation of future studies. It also broadens our knowledge of SSc pathophysiology.
Human rights violations are associated with forcibly displaced population’s mental health—a systematic review and meta-analysis
Authors: Sisenop Felix , Chatarajupalli Pallavi , Bain Paul A. , Kaade Hanna , Lindert Jutta 
Published: January 2025

BackgroundLittle is known about the mental health consequences of human rights violations in forcibly displaced populations. Objective: The objectives of this systematic review are to examine: (1) the prevalence of mental health conditions among forcibly displaced persons; (2) to investigate methodological factors contributing to mental health conditions; and (3) associations between mental health conditions and human rights violations.MethodsWe conducted a systematic review with meta-analyses on the prevalence of anxiety, depression, and posttraumatic stress disorder among forcibly displaced populations and factors contributing to it by searching in databases MEDLINE (Ovid), Embase, Web of Science Core Collection (Clarivate), PsycINFO (EBSCO), Sociological Abstracts (ProQuest), and PTSDPubs (ProQuest). Additionally, we assessed the Global Peace Index. Pooled associations were calculated using a random-effects meta-analysis model. Subgroup analyses were performed for the Global Peace Index, sampling methodology, also we assessed risk of bias.ResultsOf the 8,555 records screened, 55 with n = 31,573 participants met the inclusion criteria (n = 15,714 males, females, n = 15,859 females). Most studies were cross-sectional (n = 49). The pooled prevalence rates were 38.90% (95% CI: 29.63; 48.17) for anxiety, 38.16% (95% CI: 32.16; 44.15) for depression and 39.62% (95% CI: 32.87; 46.36) for posttraumatic stress disorder. Analyses by level of human rights violations show anxiety, and depression prevalence rates were higher in countries with very low Global Peace Index than countries with high, moderate and low Global Peace Index (39.84% vs. 16.09%; 41.07% vs. 26.67%). Analyses by risk of bias indicate that the prevalence rate of PTSD was higher in studies with a high risk of bias compared to those with a very high risk of bias (49.27% vs. 29.79%). For anxiety, the prevalence rate was greater with random sampling compared to convenience sampling (44.71% vs. 36.87%). Depression and PTSD prevalence rates were higher with convenience sampling than with random sampling (38.67% vs. 37.70%; 42.83% vs. 35.50%).ConclusionOur review suggests that systematic continuous human rights violations are associated with mental health conditions in forcibly displaced persons. To prevent mental health conditions, it is necessary to reduce exposure to human rights violations in the countries forcibly displaced persons come from.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42017076535, PROSPERO registration: CRD42017076535.
Implementasi Pendekatan Activity Relationship Chart dalam Perancangan Tata Letak Gudang Baru untuk Memperpendek Perpindahan Material di UD. M
Authors: Divibriani Mentari , Herlina Herlina 
Published: January 2025

This research discusses the issues faced by UD M, which produces crispy brownie chips, where the finished goods warehouse often becomes overcrowded due to production reaching 253 boxes, while the warehouse capacity is only 48 boxes. Due to other factors as well, the owner decided to move all activities, starting from raw material storage, production, and finished goods storage, to another location. The problem is the absence of a layout for the new warehouse. With this issue, the author designed the factory layout based on the Shared Storage method, considering material handling and the FIFO picking system. This research aims to provide the owner of UD M with considerations for arranging the facility layout in the new building. In addition to changing the layout of the finished goods warehouse, the owner plans to relocate the factory. The author reorganized the new factory of UD. M based on the results of the Activity Relationship Chart.(ARC). The research results show that the raw material warehouse, which initially measured 11.30 m², has been reduced to 10.32 m². Then, the finished goods warehouse, which initially could only hold 48 boxes, can now hold up to 123 boxes per day. By changing the layout of the production area, the production flow also becomes more organized and systematic.
Keywords: ARC, FIFO, Production Flow, Share Storage, Warehouse
Familles et individus à l’épreuve
Authors: Soulas Nicolas 
Published: January 2025

Comment devient-on « Montagnard » et ami intime de Robespierre ? Comment une famille d’anciens protestants, menacée de déclassement après la révocation de l’édit de Nantes, trouve-t-elle les moyens de se réinventer tout au long du xviiie siècle ? Quels sont les outils et les stratégies qui permettent aux individus de s’approprier le virage révolutionnaire, de s’adapter, et de s’affirmer dans le nouvel ordre institutionnel ? Comment la Révolution est-elle vécue en coulisses, dans l’intimité de la cellule familiale et des relations sociales ? Comment, enfin, survivre au 9 thermidor et se recycler dans la société postrévolutionnaire lorsque l’on est marqué du sceau infamant de « robespierriste » et renvoyé à une identité « terroriste » lourdement condamnée ? C’est à toutes ces questions que se propose de répondre cet ouvrage en suivant la trajectoire de quatre générations de la famille Payan, originaire de Saint-Paul-Trois-Châteaux dans la Drôme, entre 1685 et 1852.
Implementation of sustainability in human resource management: A literature review
Authors: Banga Chantal M. , Gobind Jenika 
Published: January 2025

Orientation: Truly, organisations face the challenge of implementing sustainability in their daily activities.Research purpose: This article examines the ways in which sustainability has been implemented in human resource management (HRM).Motivation for the study: Sustainability has become increasingly important in organisations, particularly regarding HRM.Research approach/design and method: This study used qualitative methodology and collected data by means of an integrative literature review that retrieved appropriate and relevant journal articles from the Business Source Ultimate database, as one of the EBSCOhost databases.Main findings: The findings suggest that green human resource management (GHRM) was the most frequently implemented concept and was combined with rare cases of corporate social responsibility (CSR) implementation. Sustainable human resource management (SHRM) was seldom implemented.Practical/managerial implications: Interestingly, contemporary studies revealed the circular economy (CE) as an economic sustainability dimension in HRM, and likewise, the ascendance of sustainable development goals (SDGs) in HRM. Regarding the process of sustainability implementation in HRM, some links have been established between sustainability dimensions and HRM, but the incorporation of sustainability into HRM was not evident from the reviewed literature.Contribution/value-add: This article ends with a discussion of some insights for future research. Moreover, the selection of sustainability and HRM in this article was significant given that sustainability can contribute towards a way of addressing and solving environmental, social and economic problems associated with organisations’ activities that could be fixed by HR. This demonstrates the existing strong compatibility between sustainability and HRM because HRM could fit in each sustainability dimension.
A Review of Paediatric Radiation Exposure from Diagnostic Imaging in Saudi Arabia
Authors: Aleid Abdulsalam Mohammed , Alzahrani Bayan , Sindi Mase , Alharbi Raghad , Alghamdi Shatha , Alaradi Lujain Mohammed , Almutairi Abdulmajeed , Alawad Fatema Hani , Alwahhabi Aljohara , Alsubhi Mohammed Ahmed 
Published: January 2025

Abstract

Background:
The use of diagnostic imaging in paediatrics has continued to rise which has raised concerns amongst healthcare professionals and researchers on the effects of ionising radiation in the treatment process, especially on the children. This review thus summarises what is known to date about paediatric radiation exposure in the KSA, and worldwide, the type, degree and frequency of imaging procedures employed, potential health risks involving radiation exposure and current trends. Diagnostic imaging in paediatric has been on the increase in the recent past and this has raised many questions on the impact of using ionising radiation amongst children. It is aimed at identifying the types and numbers of imaging prepped in the KSA, and globally, the level of radiation involved in these procedures and the related potential risks and trends. The main objective is to systematically and meta-analysis the literature data of the Saudi children flying to radiation. At the same time, the work analyses the gaps in knowledge, potential for further research and cases where Saudi practices can be considered non-compliant.

Methods:
The PubMed, Scopus and Web of Science were used to search for articles using the following keywords: paediatric imaging, radiation exposure, Saudi Arabia, paediatric radiation exposure, paediatric health implications and paediatric imaging safety measures.

Results:
Research has shown that there is a high use of high-dose diagnostic imaging in children with a higher likelihood of carcinogenic and neurotoxic effects such as leucaemia and impaired memory. The review also finds out that there are no detailed protocols of radiation precautions employed in the health care sector in Saudi Arabia, which is an area of concern as it may result in overexposure to radiation.

Conclusions:
The findings of the research indicate a need for policy change as well as increased education on ways of minimising the risks of paediatric diagnostic imaging in Saudi Arabia. It is also about the time that the healthcare organisations in the KSA emulate the best practices applicable in the management of patient safety from other regions to lessen the uptake of ionising radiation.
Bisphosphonates and Fracture Healing Efficacy: A Cross-sectional Study on Bone Health in Adults Over 50 in Saudi Arabia
Authors: Aleid Abdulsalam Mohammed , Alguizzani Nada Yousef , Al Anazi Mousa Musaad , Alburayman Kawther Yousif , Busaleh Hassan Abdulkhleq , Alhathlol Hussam Ali , Aldanyowi Saud Nayef 
Published: January 2025

Abstract

Introduction:
The study begins with a broad context of osteoporosis, a systemic skeletal disorder characterised by reduced bone mass and deterioration of bone tissue, presenting a significant public health challenge worldwide. Bisphosphonates, drugs that inhibit bone resorption, have emerged as a cornerstone in the management of osteoporosis. However, the efficacy of bisphosphonates significantly hinges on patient adherence to medication. The objective of this study is to ascertain the extent to which bisphosphonate adherence influences fracture healing time and changes in bone mass density, particularly considering the diverse responses observed in various populations.

Methods:
This cross-sectional study was conducted in Saudi Arabia from July to November 2023. The study population consisted of 1488 individuals aged 50 years and older who were undergoing bisphosphonate therapy. Data were collected through structured questionnaires and dual-energy X-ray absorptiometry (DXA) scans. The inclusion criteria were patients aged 50 and older, residing in Saudi Arabia, undergoing bisphosphonate therapy, adhering to their medication and having a history of fractures. Exclusion criteria applied to those who did not meet these conditions and those who declined to participate.

Results:
The study surveyed 1488 individuals, revealing key demographic characteristics. The results highlighted the significant impact of bisphosphonate therapy on fracture risk reduction and improved bone mineral density (BMD). Key findings include the relationship between bisphosphonate use and fracture healing, the prevalence of fracture amongst participants and the association between bisphosphonate therapy and BMD.

Conclusion:
This study emphasises the significant impact of bisphosphonate therapy on reducing fracture risk and improving BMD amongst adults over 50 in Saudi Arabia. It also highlights the importance of patient adherence to medication, suggesting a need for comprehensive patient education and adherence strategies. Bisphosphonates show promise in enhancing fracture healing and bone health, contributing to better clinical outcomes.
A Systematic Review and Meta-analysis Evaluating the Efficacy of Modified Aktin Diet in Patients with Epilepsy
Authors: Alqahtani Wasan Ibrahim , Alenazi Sarah Fahad , Alhajooj Manar Matar , Alamri Lujain Saleh A. , Al Jarad Alhanouf Awad , Majrashi Ashwaq Bishi , Alnasser Mohammed Nasser , Alhodibi Mostafa Habeeb 
Published: January 2025

Abstract

Background:
Since the 1920s, the ketogenic diet (KD), which is high in fat and low in carbohydrates, has been utilised to treat refractory epilepsy. Less stringent KDs, such as the modified Atkins diet (MAD), have garnered increased attention in the last few decades (MAD).

Methods:
We conducted this systematic review and meta-analysis in accordance with the guidelines outlined in the Cochrane Handbook for Systematic Reviews of Interventions as well as adhering to the recommendations set forth by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.

Results and Conclusion:
There is a statistically significant difference between KD group in comparison to the control group P = 0.0001 regarding the reduction of seizure frequency.
Bioactive components of <i>Syzygium aromaticum</i> bud and their effects on selected pathogenic bacteria
Authors: Mohammed A. , Ahssana H.J. , Balogu T.V. , Mohammed I.L. , Badeggi U.M. , Mohammed Sulaiman 
Published: January 2025

Background: The decline in the effectiveness of common antibiotics is due to microbial resistance and has sparked research interest in discovering new antimicrobial agents from plants. The objective of this study was to evaluate the effectiveness of clove extracts on selected pathogenic bacteria and identify the active antibacterial components.
Methodology: The active components of Syzygium aromaticum (clove) buds were extracted using methanol and ethyl acetate and identified by Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Antibacterial screenings against selected pathogenic bacteria were conducted using the agar-well diffusion method.
Results: The extracts showed activities against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa at 100 mg/ml, so that the diameters of the methanol extracts were 4.00-25.00 mm, 3.00-26.00 mm and 0.00 -16.00 mm, while the ethyl acetate extracts were 3.00-24.00 mm, 4.00-22.00 mm and 0.00-14.00 mm respectively. The ethyl acetate extract showed higher MIC and MBC at 3.125 and 6.5 mg/mL and 12.5 mg/mL, indicating a more lethal effect than the methanol extract. Nineteen bioactive compounds were identified the extracts.
Conclusion: The study justifies the use of the clove plant by traditional herbalists to treat bacterial infections due to the presence and synergy of the plant's various bioactive components.