bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do the effects of the DIP payment reform work for patients in the same city who are not yet covered by the reform? Evidence from Guangzhou, China
Authors: Wang Yuhao , Huang Xiaoqing , Xu Xin , Wang Lina , Lu Nana , Xu Wei 
Published: May 2023

Abstract
Background
The Reform of medical insurance payment methods is one of the crucial measures for controlling irrational medical practices. In China, the National Health Insurance Administration requires a full switch from the existing fee-for-service payment to DRG or DIP payments by 2025. Guangzhou, a city with a more developed economy and abundant medical resources in China, has completed the DIP payment reform for local-insured patients since 2018. However, patients from other-insured-region have not yet been included in the reform and still retain fee-for-service payment. This paper intends to prove that if DIP payment reform for local patients has made some effects and can these effects be simultaneously applied to the other-insured-region patients who are not covered by the payment reform.
Methods
The data in this paper were obtained from the database of basic medical insurance for urban employees of local and the other-insured-region patients in Guangzhou provided by the Guangzhou Healthcare Security Administration from 2017 to 2019. We used the average inpatient cost and the average rate of cost belonging to the medical insurance catalog to evaluate the changes in inpatient costs and reimbursement levels for both groups of patients before and after implementing the DIP payment reform. Single-group and multi-group interrupted time series were used to analyze the indicators.
Results
(1) After the DIP payment reform, local patients’ average inpatient costs fluctuated less between months compared with those before the policy implementation. (2) The average rate of cost belonging to the medical insurance catalog for local patients reflected a short- and long-term decreasing trend after the policy implementation, suggesting that patients’ burden increased and patients failed to enjoy the reform dividends. (3) The average inpatient costs of the other-insured-region patients were higher than those of local patients before and after the policy. The restraining effect on medical costs of the other-insured-region patients was not significant. (4) The average rate of cost belonging to the medical insurance catalog of the other-insured-region patients was lower than that of local patients, and after the implementation of the policy, although this indicator showed a significant downward trend in the long-term trend, but for some diseases was equal to or even higher than that of local patients.
Conclusions
On one hand, DIP payment reform for local patients has achieved some success, but still need further strengthening of regulation. On the other hand, the reform’s effect has not been synchronized with the effect on the other-insuerd-region patients. There is a risk that hospitals will pass on the payment reform cost to the other-insuerd-region patients.
Evaluating the carnivorous efficacy of Utricularia aurea on the larval stages of Anopheles stephensi, Culex quinquefasciatus and Aedes aegypti
Authors: Mohanty Ajeet Kumar , Govekar Abhishek , Souza Charles , Mohapatra Abhipsa , Janarthanam Malapati Kuppuswamy , Vukanti Raja , Nina Praveen Balabaskaran 
Published: May 2023

Abstract
Background The emergence of insecticide resistance in mosquitoes necessitates the exploration, development and validation of alternative and sustainable biological strategies for controlling mosquitoes in their natural environments.Methods We assessed the predatory effect of Utricularia aurea, an aquatic carnivorous plant found in the Indian sub-continent, Japan, and Australia, on four instar (larval) stages of Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus, in the laboratory and field settings.Results In the laboratory, within twelve hours, U. aurea predated ~ 95% of the 1st, 2nd, and 3rd instars of the three mosquito species, ~ 80% of the 4th instars of Ae. aegypti and An. stephensi and ~ 60% of 4th instars of Cx. quinquefasciatus. The predatory effect of U. aurea significantly varied among the three mosquito species and their instar stages. The effect of U. aurea on the instars of Cx. quinquefasciatus differed significantly from that on the instars of Ae. aegypti and An. stephensi. The effect of U. aurea on the 4th instars was significantly lower than that on the 1st, 2nd, and 3rd instars of the mosquitoes. The effect of U. aurea was higher during the first hour when compared to the other time points; within the first hour, U. aurea predated 58, 45, 61% of 1st instars of Ae. aegypti, An. stephensi, and Cx. quinquefasciatus, respectively. In the field settings, at the end of 16 days, U. aurea predated 71 and 76% of the immature Ae. aegypti and An. stephensi respectively.Conclusion Our findings suggest U. aurea can be utilized as a potential bio-larval control agent in natural environments; however, the current claim warrants additional investigations in different natural transmission settings .
Preoperative psychological competitive ability is associated with emotional states six months after anterior cruciate ligament reconstruction with hamstring autograft: A prospective study
Authors: Sengoku Takuya , Nakase Junsuke , Yoshimizu Rikuto , Kimura Mitsuhiro , Kanayama Tomoyuki , Kitaoka Katsuhiko 
Published: May 2023

Abstract
Background
Psychological state has been reported as one of the factors strongly related to return to sports after anterior cruciate ligament (ACL) reconstruction. However, its relationship with the emotional state remains unclear. This study aimed to investigate whether the preoperative psychological competitive ability is related to emotional states preoperatively and six months after ACL reconstruction.
Methods
Patients with a Tegner activity level of six or higher who underwent ACL reconstruction between 2015 and 2020 were divided into two groups according to their scores on the Diagnostic Inventory of Psychological Competitive Ability for Athletes (DIPCA.3) score. The emotional states preoperatively and at six months postoperative were assessed using the Profile of Mood States, 2nd Edition (POMS2) and compared between the groups. In addition, the possibility of returning to sports was compared between the groups based on participation in the entire practice 6 months postoperatively.
Results
Eighty-four patients were included and divided into high (DIPCA.3 score of 4 or higher, n = 23) and low (DIPCA.3 less than 4, n = 61) groups. Vigor-activity and friendliness were significantly higher in the high group than in the low group preoperatively. The difference was even greater at six months after ACL reconstruction. In addition, the high group showed statistically better results postoperatively for fatigue-inertia and total mood disturbance. Return to sports rates did not significantly differ between the groups (high group 56.5% vs. low group 54.1%).
Conclusion
Athletes with higher psychological competitive ability were in a positive emotional state preoperatively and six months after ACL reconstruction. However, psychological competitive ability did not affect the participation rate in the entire practice at 6 months postoperatively.
Non-anatomical double-bundle anterior cruciate ligament reconstruction combined with modified lateral extra-articular tenodesis in high-grade pivot shift anterior cruciate ligament injury：A retrospective study
Authors: Liu Xu , Li Lingzhi , Yang Haibo , Wang Zhaojun , Xie Xin , Li Zhong , Liu Juncai 
Published: May 2023

Abstract
Background: Both the non-anatomical double-bundle (DB) anterior cruciate ligament reconstruction (ACLR) and lateral extra-articular tenodesis (LET) show superior performance in controlling the rotational stability of the knee. However there are few studies published to investigate the curative effect of non-anatomical DB ACLR combined with LET in high-grade pivot shift anterior cruciate ligament ruptures. This study aims to evaluate the short-term clinical and imaging results of the treatment program and summarize the advantages of the surgical technique.
Method: All the 33 patients we reviewed in this study have accepted the non-anatomical DB ACLR with LET surgery from January 2018 to January 2022 in our Department of Orthopedics. Primary demographic data collected include gender (23 males and 10 females), age (16-37 years, average 23.5 years), BMI (21.8-31.2 kg/m2, average 25.7 kg/m2), follow-up period (12-18 months, average 15.2 months) and injury mechanism (25 sports Injuries and 8 traffic accidents). The assessment of clinical outcomes included pre- and post-operative physical examination, knee functional scores and imaging data.
Result: All patients in this study were followed up with an average 16.8-month (range 12-26 months) follow-up period. 23 patients had a grade 3 pivot shift and 10 had a grade 2 pivot shift. Immediate postoperative pivot shift tests were all negative, and only one case had a grade 1 pivot shift at the final follow-up. All the cases preoperatively had a positive Lachman test and turned negative at the final follow-up. The average ROM improved from 63.2°± 17.9° to 132.8°±3.6 °at the last follow-up (p<0.001); The VAS score decreased from 5.6±1.8 to 0.9±0.7 (p<0.001); the average KT-1000 healthy-side to affected-side difference decreased from 9.3±1.6 mm to 2.2 ± 0.5 mm. The comparison of all the knee functional scores ( IKDC, Tegner scores and Lysholom ) at pre-operative and last follow-up showed a significant difference (p<0.001). None of the cases had operation-related complications except one with slight prepatellar pain.
Conclusion: Non-anatomical double-bundle anterior cruciate ligament reconstruction combined with modified lateral extra-articular tenodesis is a reliable and recommended treatment for anterior
cruciate ligament rupture with high-grade pivot shift, showing a striking improvement in knee rotational Stability and function in the short-term follow-up.
Study on the photocatalytic degradation of rhodamine B by g-C3N4 /Bi2Fe4O9 heterojunction photocatalyst
Authors: Qi Shuyan , Guan Ling , Zhang Ruiyan , Wu Shanqiang , Zhang Kaiyao 
Published: May 2023

Abstract
G-C3N4/Bi2Fe4O9 composite photocatalysts were prepared by mechanica mixing-calcination and coprecipitation-hydrothermal method. The heterojunction structure formed by the composite of the two materials made it difficult for photogenerated electrons and holes to reunite, and improved the degradation rate of RhB. At 240 min, 25%-g-C3N4/Bi2Fe4O9 photocatalytic degradation efficiency of 10 mg/L RhB was good, reaching to 87.59%. The reaction rate constant was 0.00674 min-1, which was 2.53 times and 2.32 times that of Bi2Fe4O9 and g-C3N4. Superoxide radical (O2-·) and ·OH were the main active components in the dye degradation process.
Biochemical and molecular fine tuning of antioxidative enzyme in Solanum lycopersicum under the compatible and incompatible interactions with Alternaria solani
Authors: Upadhyay Priti , Singh Prabhash Chandra , Dixit Vineeta 
Published: May 2023

Abstract

Early blight caused by Alternaria solani has been recognised as a serious threat to tomato crop and can adversely affect its productivity worldwide. Studies have been performed to examine the basis of resistance in tomato crop but the progress is still limited. In the current study variations in the antioxidant parameters of three different tomato genotypes with varied resistance (high resistance, moderate resistance and high susceptibility) against Alternaria solani were observed and compared with the healthy non infected plants. Assays of several enzymes and antioxidants, namely Super oxide dismutase (SOD), Catalase (CAT), Ascorbate peroxidase (APX), Guaiacol peroxidase (GPX), and hydrogen peroxide (H2O2) were performed along with the expression analysis of genes encoding these enzymes. The enzymes and metabolites showed differential responses in different genotypes, with the highest concentration of H2O2 in Arka Rakshak (AR) leaves (resistant genotype) after 24 hrs of infection. On the other hand, there were significantly lower levels of H2O2 in CO-3 (highly susceptible genotype) and Pusa Ruby (moderately susceptible genotype). Similarly, SOD, APX, and CAT activities were also found to be highest in the inoculated leaves of the AR genotype. The activity of GPX was highest in Pusa Ruby at 72 hr. Hence, it can be concluded that the early blight tolerance in AR was at least partially due to the increased activities of SOD, APX and CAT under infected state as compared to those of Pusa Ruby and CO-3 genotype. The result suggests that there is a correlation between constitutive induced levels of these enzymes and plant resistance which could be considered as a biochemical markers for studying the plant-pathogen compatible and incompatible interactions.
To sleep perchance to dream - not; Nyctophobia from COVID-19 induced hyposmia: A case report
Authors: Kalita Shweta , Birwatkar Drushti , Mehdiratta Nikita , Cosme Rosario , Hirsch Alan Richard 
Published: May 2023

Abstract
Background: Increase awareness of the correlation between nyctophobia and hyposmia in individuals with COVID-19. Fear of sleep (nyctophobia) has been attributed to various conditions ranging from benign nocturnal panic attacks and Morvan's syndrome. Positional dependent hyposmia as an origin of nyctophobia has not heretofore been described.
Case presentation: This 52-year-old woman presented with sudden onset of loss of smell and taste with COVID-19, which returned to 85% of normal. However, her symptoms worsened when she would lie down to 30% of normal but would improve with standing, moving, and sitting. Requiring her to stand for hours before her sense of smell would return led to her nyctophobia that forced her to move around all the time.
Conclusions: Nyctophobia, a fear of positional dependent loss of smell, highlights the importance of smell to a narcissistic perception of self. This can be understood that the olfactory lobe is anatomically part of the limbic system. Deposition of memory engrams is facilitated as manifest with olfactory evoked nostalgia seen in 84% of the general population. The importance of smell is thus intrinsic to an individual's well-being, and the threat of loss of such sensation with a change in position with sleep was the precipitating event leading to nyctophobia in this subject. Assessing for fear of loss of smell in those with nyctophobia, especially with past COVID-19 infection, allows for an increased understanding of etiology and indicates potential treatment approaches.
Significance of Worst Pattern of Invasion 5 in Early-Stage Oral Cavity Squamous Cell Carcinoma
Authors: Mohamed Shima , Jawad Hadeel , Sullivan Ryan O' , Callanan Deirdre , Sheahan Patrick , Feeley Linda 
Published: May 2023

Abstract
Background
There is an ongoing need to identify pathologic prognosticators in early-stage oral cavity squamous cell carcinoma (OCSCC) to aid selection of patients who may benefit from adjuvant treatment. The objective of this study was to evaluate the prognostic ability of worst pattern of invasion 5 (WPOI-5) defined by the presence of satellite nodules, extratumoural perineural invasion (PNI) and/or extratumoural lymphovascular space invasion (LVI) in low-stage, node negative OCSCC.
Methods
Retrospective study of 160 patients with T1/T2N0 tumours staged using TNM7 treated surgically. Histologyof the primary tumour was re-reviewed as appropriate to assess for the presence of WPOI-5 parameters. Univariate and multivariate analysis assessing impact of pathological features on survival outcomes was performed
Results
On univariate analysis WPOI-5 and it’s 3 constituent components of satellite nodules, extratumoural PNI and extratumoural LVI were all significantly associated with disease-specific survival (DSS) and overall survival (OS). On multivariate analysis satellite nodules (odds ratio, 3.58, 95% CI 1.34, 9.55, p=0.01) and extratumoural LVI (odds ratio 10.94, CI 2.22, 53.79, p=0.003) were independently associated with OS. Postoperative radiotherapy was also significantly associated with OS on multivariate analysis (odds ratio 0.42, CI 0.19, 0.89, p=0.02).
Conclusion
Satellite nodules and extratumoural LVI correlated significantly with survival outcomes in our early-stage OSCC cohort. Further study is required to investigate the benefit of adjuvant treatment in these cases and to ascertain if worst pattern of invasion-5 parameters should be mandatory reporting data elements.
Effect mono-ADP-ribosylation on lipid metabolism of colorectal cancer by regulating IGFBP1 methylation
Authors: Wang ChuanLing , Tang Yi , Zhang ShuXian , Xiao Ming , Li Ming , Yang Lian , Li QingShu , Li Xian , Wang YaLan 
Published: May 2023

AbstractIn the global health community, colon cancer (CRC) is a major concern, with a high rate of incidence. Epigenetics is recognized as one of the causes of CRC development and progression. Mono-ADP-ribosylation (MARylation) is a type of epigenetics, although the modification level and the target protein in CRC remain unclear. We previously reported that the MARylation of arginine-117 of histone 3 (H3R117) promotes the proliferation, upregulates methylation of tumor suppressor gene, and is tightly associated with the metabolic processes in LoVo cells. Lipid metabolism disorder is involved in the development of CRC at the early stage. Our study revealed that MARylation of H3R117 of the LoVo cells modulated lipid metabolism, increased cholesterol synthesis, promoted lipid raft (LR) protein IGF-1R distribution, and inhibited cell apoptosis through IGFBP1. In addition, bioinformatics analyses revealed that the IGFBP1 promoter was hypermethylated in CRC when compared to that in normal tissues. Moreover, H3R117 MARylation upregulated the methylation of IGFBP1 promoter through histone H3 citrullination (H3cit) by increasing the H3K9me2, heterochromatin protein1 (HP1), and DNA methyltransferase 1 (DNMT1) enrichment of IGFBP1 promoter. Accordingly, IGFBP1 may function as a tumor suppressor gene, while H3R117 MARylation may promote CRC development. Our study findings enrich the available data on epigenetics of CRC and provide a new idea and experimental basis for H3R117 MARylation as a target in CRC treatment.
Ultra-broadband illusion acoustics for space and time camouflages
Authors: Liu Chenkai , Ma Chu , Lai Yun , Fang Nicholas 
Published: May 2023

Abstract

Invisibility cloaks that can suppress wave scattering by objects have attracted a tremendous amount of interest in the past two decades. In comparison to prior methods that were severely limited by narrow bandwidths, here we present a practical strategy to suppress sound scattering across an ultra-broad spectrum by leveraging illusion metamaterials. Consisting of a collection of subwavelength tunnels with precisely crafted internal structures, this illusion metamaterial has the ability to guide acoustic waves around the obstacles and accurately recreate the incoming wavefront on the exit surface. Remarkably, two ultra-broadband illusionary effects are produced: “disappearing space” and “time shift”. Sound scatterings are removed at all frequencies below a limit determined by the tunnel width, as confirmed by full-wave simulations and acoustic experiments. Our approach establishes a metamaterial platform that enables the long-desired ultra-broadband sound manipulation such as acoustic camouflage and reverberation control, opening up exciting new possibilities in practical applications.
Contribution of Sentinel-5P satellite images for the monitoring of aerosol particles in Benin
Authors: GBODJINOU Yéhounko Bruno Buffon , ZAKARI Soufouyane , AKOTON Pérugine , IMOROU Ismaïla TOKO 
Published: May 2023

Abstract
This study aims to map aerosol particles on Beninese territory from Sentinel-5P satellite images. In the absence of a ground-based measurement network, remote sensing becomes the tool for monitoring and predicting air quality to understand the environmental and health risks of aerosol particle emissions into the atmosphere. A total of 36 images of the Sentinel-5P's TROPOMI (TROPO spheric Monitoring Instrument) sensor of the year 2019 were acquired. The methodology adopted and based on the calculation of the aerosol index made it possible to extract the aerosol cards. Thus, the results obtained prove the usefulness of Sentinel-5P images in detecting aerosol particles. The maximum value of the aerosol index was recorded in February (AI = 1.859) for a minimum value of -3.3687, recorded in August. The wet June-July-August period impacts on the distribution of these air pollutants related to the leaching process unlike the dry period February-March-April during which concentrations are maximum. Periods of high concentrations of particles thus present a high risk of respiratory diseases, especially in the northern part of Benin. Measures must therefore be taken to limit respiratory risks during these months of drought through a geographical early warning system by combining ground-based measurements with satellite data for real-time monitoring.
Impacts of climate and land use/cover change on mini-hydropower generation in River Kyambura watershed in South Western part of Uganda
Authors: Aruho Tusingwiire Musa , Tumutungire Martin D. , Sempewo Jotham Ivan , Semiyaga Swaib 
Published: May 2023

Abstract

This study explored the combined impacts of climate and land-use change on mini-hydropower generation in the Kyambura watershed. The soil and water assessment tool (SWAT) was used as a hydrological model whereas the statistical downscaling model (SDSM) was used to downscale meteorological data for the Kyambura watershed for the year 2050. The results show that there will be an increase in urban land by 11.89%, barren land by 25.78%, water by 0.49% and a reduction in percentage area coverage of vegetation by 38.17% by the year 2050. A 10.6 and 17.7% increase is anticipated in average annual hydropower generated by the year 2050. There is, therefore, a need to develop governing policies to regulate management practices to preserve the integrity of the watersheds and ensure the reliability of power production.