bluuebunny/crossref_metadata_2025_split huggingface dataset:
EDUCAÇÃO DE JOVENS E ADULTOS, ENSINO DE BIOLOGIA, TEORIA HISTÓRICO-CULTURAL E PEDAGOGIA HISTÓRICO-CRÍTICA: RELAÇÕES EM PESQUISAS DE PÓS-GRADUAÇÃO
Authors: Martins de Avelar Lucas , De Deus Paranhos Rones 
Published: April 2023

Este estudo é o desdobramento de uma investigação de mestrado e objetiva analisar as relações entre a Educação de Jovens e Adultos, o Ensino de Biologia, a Teoria Histórico-Cultural (THC) e a Pedagogia Histórico-Crítica (PHC) em pesquisas de pós-graduação brasileiras com propostas de intervenção didática. Empregou-se a metodologia do Estado do Conhecimento, com recorte temporal de 1997 a 2019 e seleção das produções no Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). Foram selecionadas e analisadas 15 dissertações. Os resultados indicam que a THC e PHC não se configuram nos principais referenciais das pesquisas e seu emprego ocorre de forma majoritariamente incidental. Os nexos estabelecidos pelos trabalhos são insipientes e focalizam o cotidiano e as experiências de vida dos sujeitos. Defende-se a necessidade de uma abordagem teórico-epistemológica a partir do Materialismo Histórico-Dialético, na qual a Teoria Histórico-Cultural e a Pedagogia Histórico-Crítica sejam mediação viva para os vínculos sintéticos entre o conhecimento biológico e a modalidade, em uma perspectiva de organização do ensino-aprendizagem para o desenvolvimento humano omnilateral.
Palavras-chave: EJA. THC. PHC. Conhecimento biológico. Estado do conhecimento.

ABSTRACT
Este estuThis study is the unfolding of a master's investigation and aims to analyze the relationships between Youth and Adult Education, Biology Teaching, Historical-Cultural Theory (THC) and Historical-Critical Pedagogy (PHC) in postgraduate research. Brazilian undergraduate courses with didactic intervention proposals. The State of Knowledge methodology was used, with a time frame from 1997 to 2019 and selection of productions in the Catalog of Theses and Dissertations of the Coordination for the Improvement of Higher Education Personnel (CAPES). Fifteen dissertations were selected and analyzed. The results indicate that THC and PHC are not the main research references and their use is mostly incidental. The connections established by the works are incipient and focus on the subjects' daily life and experiences. The need for a theoretical-epistemological approach based on Historical-Dialectic Materialism is defended, in which Historical-Cultural Theory and Historical-Critical Pedagogy are living mediation for the synthetic links between biological knowledge and modality, in a perspective organization of teaching and learning for omnilateral human development.
Keywords: EJA. THC. PHC. Biological knowledge. State of knowledge.
KEMAMPUAN MANAJERIAL TERHADAP KINERJA PENGURUS BUMDES
Authors: Rusdi Muhammad , Madaling Madaling , Said Sunandar 
Published: April 2023

Pembangunan bertujuan untuk meningkatkan kemandirian taraf hidup dan kesejahteraan masyarakat, termasuk pembangunan perdesaan. Badan Usaha Perdesaan (BUMDes) adalah badan usaha komersial yang didirikan oleh pemerintah desa untuk merevitalisasi dan mengembangkan perekonomian pedesaan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kemampuan manajemen terhadap kinerja manajemen BUMDes di Kabupaten Sidenreng Rappang. Metode penelitian yang digunakan dalam penelitian ini adalah kuantitatif dengan pendekatan cross sectional. Subjek penelitian ini adalah pengelola utama BUMDes di Kabupaten Sidenreng Rappang. Pengumpulan data dilakukan dengan menggunakan alat bantu berupa kuesioner. Selain itu, data dianalisis dengan menggunakan analisis regresi linier sederhana. Hasil penelitian ini menunjukkan bahwa terdapat pengaruh yang signifikan dan positif kemampuan manajemen terhadap kinerja BUMDes di Kabupaten Sidenreng Rappang. Kata kunci: BUMDes, kemampuan manajerial, kinerja ABSTRACT Development aims to improve the independence of living standards and social well-being, including the development of rural areas. Village Enterprises (BUMDes) are commercial enterprises established by village governments to revitalize and develop the rural economy. The purpose of this study was to determine the effect of management ability on management performance of BUMDes in Sidenreng Rappang Regency. The research method used in this study is a quantitative, cross-sectional approach. The subject of this study is the principal manager of BUMDes at the Sidenreng Rappang Regency. Data were collected using the tool in the form of a questionnaire. In addition, data were analyzed using simple linear regression analysis. The results of this study showed that there was a significant and positive impact of management ability on the performance of BUMD in Sidenreng Rappang Regency. Keywords: BUMDes, Managerial Ability, Performance.
DAMPAK NILAI PERUSAHAAN YANG DIPENGARUHI KEPUTUSAN INVESTASI, STRUKTUR MODAL, DAN KEBIJAKAN DIVIDEN
Authors: Yunaningsih Yuyun , Widhiastuti Susanti 
Published: April 2023

Penelitian ini bertujuan untuk menguji dampak nilai perusahaan yang dipengaruhi keputusan investasi, struktur modal, dan kebijakan dividen pada perusahaan sektor industri dasar dan kimia yang terdaftar di Bursa Efek Indonesia periode 2017-2020. Data dalam penelitian menggunakan data sekunder dari 15 perusahaan sektor industri dasar dan kimia yang terdaftar di BEI. Teknik analisis menggunakan regresi linier berganda yang diolah menggunakan SPSS. Hasil penelitian ini ialah keputusan investasi berdampak positif signifikan terhadap nilai perusahaan, sementara kebijakan dividen dan struktur modal berdampak positif tidak signifikan terhadap nilai perusahaan. Kata kunci: kebijakan dividen, keputusan investasi, nilai perusahaan, struktur modal ABSTRACT This study aims to examine the impact of firm value on investment decisions, capital structure and dividend policy on basic and chemical industrial sector companies listed on the Indonesia Stock Exchange for the 2017-2020 period. The data in this study uses secondary data from 15 basic and chemical industrial sector companies listed on the IDX. The analysis technique uses multiple linear regression which is processed using SPSS. The results of this study are that investment decisions have a significant positive impact on firm value, while dividend policy and capital structure have an insignificant positive impact on firm value. Keywords: capital structure, dividend policy, firm value, investment decision
IMPAK GAYA KEPEMIMPINAN DAN MOTIVASI KERJA ATAS KINERJA KARYAWAN PADA INDUSTRI PADAT KARYA DI BOGOR
Authors: Mulyana Dede , Utama Angka , Widodo Widodo , Cecep Cecep 
Published: April 2023

Tujuan dari peneltian ini untuk melakukan uji impak gaya kepemimpinan juga motivasi kerja atas kinerja karyawan di industri padat karya di Bogor. Maka pada pelaksanaannya digunakan metode deskriptif, melakukan uji (butir pernyataan, korelasi, regresi simpel dan ganda, determinan, serta parsial, simultan). Keluaran regresi diperoleh ada impak yang nyata antara gaya kepemimpinan atas variabel kinerja karyawan. Kesimpulannya adalah gaya kepemimpinan yang baik mampu menaikan kinerja karyawan. Motivasi berpengaruh kuat atas kinerja karyawan. Hasil uji regresi diperoleh ada impak yang nyata (signifikan) motivasi atas kinerja karyawan. Artinya semakin baiknya motivasi akan meningkat pula kinerja karyawan. Gaya kepemimpinan, motivasi kerja secara simultan memiliki dampak positif atas kinerja karyawan. Kata kunci: gaya kepemimpinan, motivasi kerja, kinerja karyawan ABSTRACT The influence of leadership style and work motivation on employee performance manufacturing industry in Bogor. To apply these objectives, descriptive analysis methods, validity tests, reliability tests, correlation tests, simple regression, multiple regression, determinant tests, and partial and simultaneous tests are used. Regression obtained that there is a strong effect between leadership style on employee performance variable. A good leadership style will improve employee performance. Motivation has a significant effect on employee performance. The results of the regression analysis obtained that there is a significant (significant) influence on the motivation variable on the employee performance variable. Keywords: corporate social responsibility, entrepreneurship orientation, SME innovation
PENINGKATAN KAPASITAS SDM DAN PEMASARAN DIGITAL DENGAN MEDIASI MODAL INTELEKTUAL TERHADAP KINERJA USAHA AGRIBISNIS
Authors: Wicaksana Indrajit , Budiningsih Susilowati , Triastuti Yuli , Jayadi Jayadi 
Published: April 2023

Pandemi covid-19 memberikan dampak besar bagi usaha skala mikro, kecil, dan menengah. Kebijakan pembatasan sosial yang berskala besar akibat covid-19 berdampak pada turunnya aktivitas ekonomi, termasuk di bidang agribisnis. Strategi yang diterapkan untuk penguatan usaha di masa pandemi ini salah satunya adalah memperkuat kapasitas sumber daya manusia agar tetap bertahan dan berinovasi. Penelitian ini ditujukan untuk mengetahui pengaruh langsung dan tidak langsung peningkatan kapasitas sumber daya manusia (capacity building) dan pemasaran digital (digital marketing) terhadap peningkatan kinerja usaha agribisnis di masa pandemi covid-19 melalui mediasi modal intelektual (intellectual capital). Sampel penelitian ini mencakup 50 usaha agribisnis. Melalui penelitian ini akan diketahui pengaruh langsung dan tidak langsung capacity building pada kinerja usaha agribisnis saat covid-19. Kata kunci: agribisnis, kinerja, modal intelektual, pemasaran digital, peningkatan kapasitas ABSTRACT The Covid-19 pandemic has had an impact on micro, small and medium scale businesses. The large-scale social restriction policy due to Covid-19 has had an impact on decreasing economic activity, including in the agribusiness sector. One of the strategies implemented to strengthen business during this pandemic is to strengthen the capacity of human resources to survive and innovate. This study aims to determine the direct and indirect effects of increasing the capacity of human resources and digital marketing on improving the performance of agribusiness businesses during the Covid-19 pandemic through the mediation of intellectual capital. The sample of this research includes 50 agribusiness enterprises. Through this research, it will be known the direct and indirect effects of capacity building on the performance of agribusiness during Covid-19. Keywords: agribusiness, capacity building, digital marketing, intellectual capital, performance
PERAN KEPERCAYAAN DALAM MEMEDIASI PROMOSI ONLINE DAN BRAND IMAGE TERHADAP LOYALITAS MAHASISWA DI JAKARTA
Authors: Herlina Elin , Mulyanto Heru 
Published: April 2023

Penelitian ini untuk mengetahui peran kepercayaan dalam memediasi promosi online dan brand image terhadap loyalitas mahasiswa. Penelitian dilakukan pada mahasiswa perguruan tinggi di jakarta. Sampel diambil dengan metode random sampling dengan membagikan kuesioner kepada 87 mahasiswa. Data dari kuesioner dianalisis menggunakan software Smart-PLS. Promosi Online berpengaruh positif terhadap kepercayaan. Brand Image berpengaruh positif terhadap kepercayaan. Kepercayaan berpengaruh positif terhadap loyalitas. Kepercayaan memediasi promosi online secara positif pada loyalitas. Kepercayaan memediasi secara positif brand image pada loyalitas. Berdasarkan temuan tersebut, untuk meningkatkan loyalitas mahasiswa, disarankan agar institusi meningkatkan kepercayaan mahasiswa dengan meningkatkan Promosi Online dan Brand Image. Kata kunci: brand image, kepercayaan, loyalitas, promosi online ABSTRACT This research is to determine the role of trust in mediating the influence of online promotion and brand image on student loyalty. Research was conducted on students at universities in Jakarta. Samples were taken using the random sampling method by distributing questionnaires to 87 students. Data from the questionnaire was analyzed using smart PLS software. This study resulted in findings that: 1) Online Promotion positively affects trust; 2) Brand Image positively affects trust; 3) Trust positively affects loyalty; 4) Trust mediates online promotion positively on loyalty; 5) Trust positively mediates brand image on loyalty. To increase student loyalty, it is recommended that institutions increase student trust by increasing Online Promotion and Brand Image. Keywords: brand image, loyalty, online promotion, trust.
Clinical features and “early” corticosteroid treatment outcome of pediatric mycoplasma pneumoniae pneumonia
Authors: Liu Jinrong , He Ruxuan , Zhang Xiaoyan , Zhao Fei , Liu Liyong , Wang Heng , Zhao Shunying 
Published: April 2023

BackgroundMany children with mycoplasma pneumoniae (MP) pneumonia (MPP) developed sequelae such as bronchiolitis/bronchitis obliterans (BO). Early corticosteroid therapy might prevent disease progression. This study aimed to use “early” corticosteroid and observe the treatment outcome in patients with MPP.MethodsPatients who had pulmonary infiltrations on chest imaging within 5 days of the disease course and were suspected of having MP infection on admission were enrolled. Among them, patients whose disease course was within 10 days on admission were ultimately enrolled. We analyzed their data including the clinical features, the starting time and dose of corticosteroid therapy, and the treatment outcome. According to chest imaging, we divided patients into two groups (Group A: bronchiolitis-associated lesions or ground-glass opacities; Group B: pulmonary segmental/lobar consolidation).ResultsA total of 210 patients with confirmed MPP were ultimately enrolled. There were 59 patients in Group A and 151 patients in Group B. Patients in Group A were more prone to have allergy histories, hypoxemia, wheezing sound, and wet rales on auscultation than those in Group B. Corticosteroid treatment was initiated between 5 and 10 days of disease onset in all patients and 6–7 days in most patients. Methylprednisolone was prescribed in all patients within 10 days of disease onset, and the highest prescribed dose was at least 2 mg/kg/day. In Group A, methylprednisolone &gt;2 mg/kg/day was prescribed in 22 patients, and among them, 8 patients with diffuse bronchiolitis-associated lesions received high-dose methylprednisolone therapy. After 3 months, lung CT revealed slightly segmental ground-glass opacity in three patients. In Group B, methylprednisolone &gt;2 mg/kg/day was prescribed in 76 patients, and among them, 20 patients with pulmonary lobar consolidation received high-dose methylprednisolone therapy. After 3 months, chest imaging revealed incomplete absorption of pulmonary lesions in seven patients. Among them, five patients with consolidation in more than one pulmonary lobe ultimately had slight BO.ConclusionIn hospitalized patients with MPP, particularly severe MPP, the ideal starting time of corticosteroid treatment might be 5–10 days, preferably 6–7 days, after disease onset. The initial dosage of corticosteroid therapy should be decided according to the severity of the disease. MPP patients with diffuse bronchiolitis-associated lesions/whole lobar consolidation on imaging might require high-dose corticosteroid therapy.
A new permanent, low-cost, low-power SO2 camera for continuous measurement of volcanic emissions
Authors: Wilkes Thomas Charles , Pering Tom David , Aguilera Felipe , Layana Susana , Nadeau Patricia , Kern Christoph , McGonigle Andrew John Samuel , Aguilera Mauricio , Zhu Chengxi 
Published: April 2023

Since its introduction to volcanology in the mid-2000 s, the SO2 camera has become an important instrument for the acquisition of accurate and high time-resolution SO2 emission rates, aiding in hazard assessment and volcanological research. However, with the exception of a few locations (Stromboli, Etna, Kīlauea), hitherto the majority of measurements have been made on discrete field campaigns, which provide only brief snapshots into a volcano’s activity. Here, we present the development of a new, low-cost, low-power SO2 camera for permanent deployment on volcanoes, facilitating long-term, quasi-continuous (daylight hours only) measurements. We then discuss preliminary datasets from Lascar and Kīlauea volcanoes, where instruments are now in continuous operation. Further proliferation of such instrumentation has the potential to greatly improve our understanding of the transient nature of volcanic activity, as well as aiding volcano monitoring/eruption forecasting.
Roles of sex hormones in mediating the causal effect of vitamin D on osteoporosis: A two-step Mendelian randomization study
Authors: Du Yongwei , Xie Baohui , Wang Maoyuan , Zhong Yanbiao , Lv Zhimai , Luo Yun , He Qiwei , Liu Zhen 
Published: April 2023

BackgroundAlthough 25-hydroxyvitamin D [25(OH)D] is a risk factor for osteoporosis, it is not clear whether sex hormones mediate this casual association. We aimed to explore how sex hormones affect the association between 25(OH)D and osteoporosis to provide meaningful insights on the underlying mechanisms from a genetic perspective.MethodsGenetic variations in 25(OH)D, total testosterone (TT), androstenedione (A4), estradiol (E2), and testosterone/17β-estradiol (T/E2) were determined through summary statistics. Taking osteoporosis as the outcome (FinnGen biobank, 332,020 samples), we conducted a Mendelian randomization (MR) analysis to establish the association between 25(OH)D and these sex hormones. The two-step MR analysis quantified the mediatory effects of sex hormones on osteoporosis. The results were further verified by pleiotropy and heterogeneity analyses.ResultsMR results showed that 25(OH)D (OR= 1.27, p = 0.04) and TT (OR= 1.25, p = 0.04) had a causal effect on osteoporosis. No significant associations were observed between the other sex hormones (A4, E2, and T/E2) and osteoporosis (p&gt;0.05). Sensitivity analysis (p&gt;0.05) confirmed the robustness of the MR results. The two-step MR analysis provided evidence that the mediatory effect of TT was 0.014 (the percentage of TT mediation was 5.91%). Moreover, the direct effect of 25(OH)D on osteoporosis was 0.221. A4, E2, and T/E2 were not considered as potential mediators of the role of 25(OH)D as a risk factor for OP.ConclusionThis study, through MR analysis, showed that TT mediates the causal effect of 25(OH)D on osteoporosis. Interventions targeting TT, therefore, have the potential to substantially reduce the burden of osteoporosis attributable to high 25(OH)D.
Root-specific flavones and critical enzyme genes involved in their synthesis changes due to drought stress on Scutellaria baicalensis
Authors: Li Ping , Ren Guangxi , Wu Fei , Chen Jiaxin , Jiang Dan , Liu Chunsheng 
Published: April 2023

IntroductionScutellaria baicalensis is rich in bioactive flavonoid, which are widely used in clinical therapy. Many environmental factors, such as water and temperature, affect gene expression and secondary metabolites accumulation in plants.MethodsIn this study, to explore the effect of drought stress on the accumulation of flavonoids and gene expression in S. baicalensis seedlings, 4-week-old Scutellaria baicalensis seedlings were treated with different concentrations of PEG6000 to simulate drought stress. The contents of four root-specific flavones (baicalein, wogonin, baicalin, and wogonoside) in samples under different treatments were quantitatively analyzed by high performance liquid chromatography (HPLC). The expression levels of flavonoid biosynthesis-related genes (PAL1, PAL2, CHS, and UBGAT) were determined by real-time quantitative PCR (qRT-PCR). Also, a correlation analysis between flavonoid contents and gene expression levels was made.ResultsThe HPLC results revealed that 5 and 10% PEG6000 treatments significantly increased the content of four flavonoids, with 5% PEG 6000 treatment being the most beneficial to the flavonoids accumulation. The qRT-PCR results showed that PAL2 and CHS gene expressions differed significantly in different organs, while PAL1 and UBGAT had poor organ-specific. For genes in roots, the expression of PAL1 and UBGAT was the highest in 5% PEG6000 treatment, and PAL2 and CHS were the highest in 10% PEG6000 treatment. Compared with other concentrations of PEG6000, 5 and 10% PEG6000 were more advantageous for gene expression. Collectively, PEG6000 at a low concentration promoted the accumulation of flavonoids and the expression of related genes. Additionally, the correlation results demonstrated that PAL1, PAL2, CHS, and UBGAT genes in roots stimulated the formation and accumulation of the four flavonoids to varying degrees, while the exception of PAL2 gene expression in roots was negatively correlated with wogonin content.DiscussionThis study for the first time investigated the effect of drought stress on the downstream gene UBGAT in S.baicalensis seedlings as well as the correlation between gene expression and flavonoid content in S. baicalensis seedlings under drought stress, providing a new sight for studying the effects of drought stress on flavonoid accumulation and related gene expression in S. baicalensis.
Integrating multiple machine learning algorithms for prognostic prediction of gastric cancer based on immune-related lncRNAs
Authors: Li Guoqi , Huo Diwei , Guo Naifu , Li Yi , Ma Hongzhe , Liu Lei , Xie Hongbo , Zhang Denan , Qu Bo , Chen Xiujie 
Published: April 2023

Background: Long non-coding RNAs (lncRNAs) play an important role in the immune regulation of gastric cancer (GC). However, the clinical application value of immune-related lncRNAs has not been fully developed. It is of great significance to overcome the challenges of prognostic prediction and classification of gastric cancer patients based on the current study.Methods: In this study, the R package ImmLnc was used to obtain immune-related lncRNAs of The Cancer Genome Atlas Stomach Adenocarcinoma (TCGA-STAD) project, and univariate Cox regression analysis was performed to find prognostic immune-related lncRNAs. A total of 117 combinations based on 10 algorithms were integrated to determine the immune-related lncRNA prognostic model (ILPM). According to the ILPM, the least absolute shrinkage and selection operator (LASSO) regression was employed to find the major lncRNAs and develop the risk model. ssGSEA, CIBERSORT algorithm, the R package maftools, pRRophetic, and clusterProfiler were employed for measuring the proportion of immune cells among risk groups, genomic mutation difference, drug sensitivity analysis, and pathway enrichment score.Results: A total of 321 immune-related lncRNAs were found, and there were 26 prognostic immune-related lncRNAs. According to the ILPM, 18 of 26 lncRNAs were selected and the risk score (RS) developed by the 18-lncRNA signature had good strength in the TCGA training set and Gene Expression Omnibus (GEO) validation datasets. Patients were divided into high- and low-risk groups according to the median RS, and the low-risk group had a better prognosis, tumor immune microenvironment, and tumor signature enrichment score and a higher metabolism, frequency of genomic mutations, proportion of immune cell infiltration, and antitumor drug resistance. Furthermore, 86 differentially expressed genes (DEGs) between high- and low-risk groups were mainly enriched in immune-related pathways.Conclusion: The ILPM developed based on 26 prognostic immune-related lncRNAs can help in predicting the prognosis of patients suffering from gastric cancer. Precision medicine can be effectively carried out by dividing patients into high- and low-risk groups according to the RS.