bluuebunny/crossref_metadata_2025_split huggingface dataset:
Malignant pleural mesothelioma with constrictive pericarditis as the first manifestation: A case report
Authors: He Cheng‐Peng , Tu Di‐Wei , Zhang Ting‐Wei , Zhang Qian , Zhang Qiang , Kang Di , Wang Ying‐Ying , Li Ying‐Ying , Zhang Bin , Han Sha‐Sha , Li Hong‐Bo 
Published: June 2023

AbstractPleural mesothelioma (PM) with pericardial involvement is extremely rare. We now report a rare case of malignant PM with constrictive pericarditis as the first presentation. A 59‐year‐old male diagnosed with constrictive pericarditis underwent pericardiectomy and pericardial pathology revealed mesothelial hyperplasia. Eight months after surgery, the patient was admitted to the hospital with chest tightness and wheezing for 5 days. Computed tomography scan of the chest showed a left lung expansion insufficiency, limited bilateral pleural thickening, pericardial thickening with a small amount of pericardial effusion, and multiple enlarged lymph nodes in the mediastinum, bilateral supraclavicular fossa, bilateral cervical roots, and right axilla. The pleural malignancy should be possibly considered. Pathology after pleural puncture showed malignant PM. Pathology after left supraclavicular lymph node puncture biopsy showed metastatic malignant mesothelioma. The diagnosis of this patient was clear. Although malignant PM rarely involves the pericardial constriction, we cannot ignore the fact that malignant PM involves the pericardium. The patient has been diagnosed with constrictive pericarditis, accompanied by pleural thickening and pleural effusion. Without other pathogenic factors, pleural biopsy should be aggressively performed in patients with constrictive pericarditis to determine the cause.
A case report of a 16‐year‐old male with extrapulmonary tuberculosis presenting as multiloculated mediastinal, pleural, and paravertebral fluid collections with chest pain, Eldoret, Kenya
Authors: Maleche Maureen Aleyo , Sirera Betty , Masika Kennedy Barasa , Keitany Kibbet Kobor , Oduor Chrispine , Diero Lameck 
Published: June 2023

Key Clinical MessageExtrapulmonary TB presenting as multiloculated pleural fluid collections is rare in persons less than 18 years of age, but it can occur. High index of suspicion is important in establishing early diagnosis and treatment to reduce morbidity and mortality.AbstractWe present a case report of an immunocompetent African young man who presented with persistent chest pain and fever, and was diagnosed with extrapulmonary tuberculosis (EPTB) following chest CT scan, pleural biopsy histopathology examination, and Ziehl–Neelsen (ZN) staining, and pleural fluid Gene Xpert studies.
Percutaneous deep venous arterialization with balloon angioplasty salvaged a life‐threatening critical limb in a hemodialysis patient after repeated pedal angioplasty failed: A case report
Authors: Takagi Tomonari , Miyamoto Akira , Ohura Norihiko , Yamauchi Yasutaka 
Published: June 2023

AbstractChronic limb‐threatening ischemia (CLTI) with severe below‐the‐ankle (BTA) lesions is often difficult to revascularize with endovascular treatment (EVT) and surgical treatment. We present a case of successful limb salvage using percutaneous deep venous arterialization (pDVA) in a patient with CLTI whose BTA lesion reconstruction failed. A 57‐year‐old man with diabetes mellitus and end‐stage renal failure on maintenance hemodialysis was referred to our hospital because of gangrene in the second and third toes of his left foot. EVT was repeated for the anterior tibial artery, posterior tibial artery (PTA), dorsal foot artery, and plantar artery lesions; however, revascularization below the ankle was unsuccessful. As the infection had spread to the sole of the foot, below‐the‐knee amputation was indicated, but the patient refused. Therefore, we performed pDVA on the left PTA simultaneously with a Lisfranc amputation. An arteriovenous fistula was created at the ankle joint using a Venous Arterialization Simplified Technique and a guidewire was inserted into the plantar vein. Balloon dilatation from PTA to the plantar vein was performed to complete the pDVA. Although repeated EVT was required to maintain blood flow in the pDVA, skin grafting was performed 3 months after the pDVA, the wound completely healed, and he was discharged 6 months after the DVA. The pDVA can be an option for limb salvage in patients with no‐option CLTI who are confronted by imminent amputation.
Effective treatment of choreaballism due to an MT‐CYB variant with haloperidol, tetrabenazine, and antioxidants
Authors: Finsterer Josef , Ghosh Ritwik 
Published: June 2023

Key Clinical MessageHypokinetic and hyperkinetic movement disorders are a common phenotypic feature of mitochondrial disorders. Choreaballism has been reported particularly in patients with mitochondrial encephalopathy, lactic acidosis, and stroke‐like episodes syndrome and in maternally inherited diabetes and deafness syndrome. The pathophysiological basis of movement disorders in mitochondrial disorders is the involvement of the basal ganglia or the midbrain. Haloperidol and mitochondrial cocktails have proven beneficial in some of these cases. Here we present another patient with mitochondrial choreaballism who benefited significantly from symptomatic therapy. The patient is a 14‐year‐old male with a history of hypoacusis, ptosis, and focal tonic–clonic seizures of the upper/lower limbs on either side since childhood. Since this time he has also developed occasional, abnormal involuntary limb movements, choreaballism, facial grimacing, carpopedal spasms, and abnormal lip sensations. He was diagnosed with a non‐syndromic mitochondrial disorder after detection of the variant m.15043G > A in MT‐CYB. Seizures have been successfully treated with lamotrigine. Hypocalcemia was treated with intravenous calcium. For hypoparathyroidism calcitriol was given. Choreaballism was treated with haloperidol and tetrabenazine. In addition, he received coenzyme Q10, L‐carnitine, thiamine, riboflavin, alpha‐lipoic acid, biotin, vitamin‐C, vitamin‐E, and creatine‐monohydrate. With this therapy, the choreaballism disappeared completely. This case shows that mitochondrial disorders can manifest with cognitive impairment, seizures, movement disorder, hypoacusis, endocrinopathy, cardiomyopathy, neuropathy, and myopathy, that choreaballism can be a phenotypic feature of multisystem mitochondrial disorders, and that choreaballism favorably responds to haloperidol, tetrabenazine, and possibly to a cocktail of antioxidants, cofactors, and vitamins.
Metal‐Organic Gels of Tris‐tetrazole‐tri‐amido Molecule with Co(II) and Ni(II) as Effective Electrocatalysts for Oxygen Evolution Reaction: Effect of Metal Ion, Porosity and Morphology on the Catalytic Activity of MOGs
Authors: Moi Rajib , Nath Karabi , Ghosh Debanjali , Biradha Kumar 
Published: June 2023

AbstractDevelopment of efficient and low cost electrocatalysts has been an important area of research in the field of materials chemistry. In this regard metal‐organic gels (MOGs) are one of the promising materials and they are being utilized for various materials applications including energy conversion and storage. Electrochemical applications of the MOGs are still in its infancy and further studies are required for exploration of structure‐property correlation that is crucial for targeted and efficient materials design. Herein we report multi stimuli responsive MOGs containing a tris‐tetrazole‐tri‐amido based organic ligand. The self‐assembly of the threefold symmetric ligand with Co(II)/Ni(II) acetates results in the MOGs with distinct morphological and structural characteristics, regardless of containing the same organic ligand. These MOGs were synthesized by direct mixing of the precursors under ambient conditions. The xerogels of these MOGs (Co‐MOG′ and Ni‐MOG′) exhibit excellent OER performance as the Co‐MOG′ and Ni‐MOG′ shows the overpotential of 312 mV and 418 mV at 10 mA/cm2 in an alkaline electrolyte. Electrocatalytic performance of the xerogels were correlated to their structural features like distinct morphology and porosity of the material that facilitates the mass transfer and maximum exposure to the electrochemical active sites. Importantly, this work demonstrates the functional application of MOGs as electrocatalysts for OER and the effect of metal ion, porosity and morphology on their overall performance.
Influence of Glycyl‐L‐Glutamic Acid Dipeptide on Calcium Pyrophosphate Dihydrate Crystallization
Authors: Polat Sevgi , An Qi , Eral Huseyin Burak 
Published: June 2023

AbstractThe increasing prevalence of calcium pyrophosphate dihydrate (CPPD) deposition disease, a form of arthritis with high inflammatory potential, has triggered considerable interest in the search for additives to prevent CPPD crystal formation, particularly in the field of biomineralization. In this context, CPPD crystallization in aqueous solution with and without glycine, glutamic acid, or glycyl‐L‐glutamic acid as crystal‐growth modifier was experimentally investigated. The produced crystals were characterized structurally, morphologically, and in terms of their surface charge. In addition, the thermal degradation profiles of CPPD crystals obtained with and without the modifiers were characterized by TGA‐FTIR, and the major volatile product was H2O.
Durable hierarchical phosphorus‐doped biphase MoS2 electrocatalysts with enhanced H* adsorption
Authors: Qian Yongteng , Yu Jianmin , Lyu Zhiyi , Zhang Qianwen , Lee Tae Hyeong , Pang Huan , Kang Dae Joon 
Published: June 2023

AbstractPhase engineering is an efficient strategy for enhancing the kinetics of electrocatalytic reactions. Herein, phase engineering was employed to prepare high‐performance phosphorous‐doped biphase (1T/2H) MoS2 (P‐BMS) nanoflakes for hydrogen evolution reaction (HER). The doping of MoS2 with P atoms modifies its electronic structure and optimizes its electrocatalytic reaction kinetics, which significantly enhances its electrical conductivity and structural stability, which are verified by various characterization tools, including X‐ray photoelectron spectroscopy, high‐resolution transmission electron microscopy, X‐ray absorption near‐edge spectroscopy, and extended X‐ray absorption fine structure. Moreover, the hierarchically formed flakes of P‐BMS provide numerous catalytic surface‐active sites, which remarkably enhance its HER activity. The optimized P‐BMS electrocatalysts exhibit low overpotentials (60 and 72 mV at 10 mA cm−2) in H2SO4 (0.5 M) and KOH (1.0 M), respectively. The mechanism of improving the HER activity of the material was systematically studied using density functional theory calculations and various electrochemical characterization techniques. This study has shown that phase engineering is a promising strategy for enhancing the H* adsorption of metal sulfides.
Integration of machine learning and data analysis for the SAGD production performance with infill wells
Authors: Huang Ziteng , Yang Min , Chen Zhangxin 
Published: June 2023

AbstractThere have been numerous studies on predicting the production performance of the steam assisted gravity drainage (SAGD) process by data‐driven models with different machine learning algorithms since their introduction into industry. Similar efforts on SAGD infill wells, nevertheless, remain rare for this advanced alteration in improving the classical SAGD performance. On the other hand, predictive tools to optimize an infill well start time is useful in maximizing bitumen production and minimizing its costs. In this paper, a series of SAGD infill well models are constructed with selected ranges of operational conditions. Three SAGD infill well production performance indicators, namely, an increased ratio (), a total steam–oil ratio (SORtotal), and a stolen ratio () for each SAGD infill well, are calculated based on simulated infill well cases and control models. Five different machine learning algorithms (an artificial neural network [ANN] algorithm, three gradient boosting decision tree [GBDT] algorithms, and a support vector machine [SVM] algorithm) are trained, tested, and evaluated for their effectiveness in predicting those three indicators as output parameters, given seven SAGD relevant parameters as input parameters. Comparisons of different data sets show that the ANN is the best in predicting all three performance indicators under different infill well start times among all the above machine learning algorithms, while the GBDT algorithms have a better ability to learn a variation trend in the SAGD infill well performance.
Less is more – an efficient photoreactor on the nanoscale
Authors: Petersen Malte , Nau Roland E. P. , Pannwitz Andrea , Wilke Timm 
Published: June 2023

AbstractPhotochemische Prozesse sind die Grundlage des Lebens auf der Erde. In der aktuellen Forschung wird Sonnenlicht verstärkt genutzt, um “grünen” Wasserstoff zu erzeugen. Hierfür werden Photosysteme entwickelt, die möglichst effizient und langlebig arbeiten sollen. Eine innovative Methode zur Leistungssteigerung ist der Einschluss solcher Photosysteme in sogenannte Liposom‐Nanoreaktoren. Durch die räumliche Nähe können lokal hohe Konzentrationen der Reaktanden gebildet und Leistungsfähigkeit, Lebensdauer sowie Effizienz deutlich gesteigert werden. Die vorgestellte Experimentalreihe knüpft an aktuellen wissenschaftlichen Forschungen im Bereich der Photochemie an und erschließt das zentrale Prinzip für die Schulen und Schülerlabore. Hierfür wird ein photochemisches System aus Eosin Y und NADH in Liposom‐Nanoreaktoren bestehend aus Lecithin eingeschlossen und die Leistung mit einem System ohne Nanoreaktoren verglichen. Bereits nach 5 Minuten Belichtungszeit zeigt das System eine signifikant bessere Leistung, die sogar mit dem Vorbild aus der Forschung vergleichbar ist.
Spatial Patterning of Micromotor Aggregation and Flux
Authors: Rivas David P. , Sokolich Max , Das Sambeeta 
Published: June 2023

AbstractUsing a spatially varying light pattern with light activated semi‐conductor based magnetic micromotors, we study the difference in micromotor flux between illuminated and non‐illuminated regions in the presence and absence of an applied magnetic field. We find that the magnetic field enhances the flux of the motors which we attribute to a straightening of the micromotor trajectories which decreases the time they spend in the illuminated region. We also demonstrate spatially patterned light‐induced aggregation of the micromotors and study its time evolution at various micromotor concentrations. Although light induced aggregation has been observed previously, spatial patterning of aggregation demonstrates a further means of control which could be relevant to swarm control or self‐assembly applications. Overall, these results draw attention to the effect of trajectory shape on the flux of active colloids as well as the concentration dependence of aggregation and its time dependence within a spatially patterned region, which is not only pertinent to self‐assembly and swarm control, but also provides insight into the behavior of active matter systems with spatially varying activity levels.
In vitro comparison of the physical and mechanical properties of an ormocer with an ormocer‐based composite and a nanocomposite restorative material
Authors: Jansen van Rensburg Karien , Kritzinger Dorette , Arnold Samantha , Buchanan Glynn D. 
Published: June 2023

AbstractObjectivesTo compare an ormocer with a first generation ormocer‐based composite and a nanocomposite in terms of surface roughness, surface hardness, and microleakage.Materials and MethodsAn ormocer (Admira Fusion), a first generation ormocer‐based composite (Admira) and a nanocomposite (Filtek Z350 XT) were prepared strictly in accordance with the manufacturer's instruction and recommendation to provide optimal material properties. Twelve disk samples of each material were evaluated to assess both surface roughness and surface hardness. For surface roughness, all samples were finished, polished, and Ra values measured with a profilometer. For surface hardness, samples were stored in an incubator, polished and a Vickers diamond indenter was used to record values. For microleakage, 36 standardized, Class V cavities were prepared and randomly divided into three groups. Restored teeth were thermally fatigued, immersed in 2% methylene blue solution for 48 h, sectioned, and scored for occlusal and gingival microleakage.ResultsStatistical significance was set at p < .05. The one‐way analysis of variance identified no significant difference in terms of surface roughness between the three material groups (p > .05). A significantly higher surface hardness was identified for the nanocomposite compared to both the ormocer (p < .001) and ormocer‐based composite (p < .001). Fisher's exact test identified no significant difference in terms of occlusal microleakage (p = .534) and gingival microleakage (p = .093) between the three material groups.ConclusionsNo significant differences in terms of surface roughness or microleakage were noted. The nanocomposite was significantly harder than the ormocer materials.
Peer influence, market power, and enterprises' green innovation: Evidence from Chinese listed firms
Authors: Gu Jiafeng 
Published: June 2023

AbstractIn the era of a green economy, green innovation has become a way for enterprises to gain competitive advantage, and it is of great theoretical and practical significance to explore the driving force of enterprises' green innovation. This study explores the peer effect of an enterprise's green innovation and conducts an empirical test using data from 3338 Chinese listed companies in 2020. The results show a significant positive peer effect of enterprises' green innovation, and the green innovation of individual enterprises increases by 0.869 for each unit increase in industry‐average green innovation. Further research shows that market power is the channel by which peer influence affects an enterprise's green innovation. Moreover, regional heterogeneity exists in the strength of the peer effect, which varies according to firm maturity and board size. These findings provide a reference for enterprises and governments to promote green transformation.
Distribution changes of non‐self‐test cells and self‐tunic cells surrounding the outer body during Ciona metamorphosis
Authors: Totsuka Nozomu M. , Kuwana Satoshi , Sawai Satoshi , Oka Kotaro , Sasakura Yasunori , Hotta Kohji 
Published: June 2023

AbstractBackground: Ascidians significantly change their body structure through metamorphosis, but the spatio‐temporal cell dynamics in the early metamorphosis stage has not been clarified. A natural Ciona embryo is surrounded by maternally derived non‐self‐test cells before metamorphosis. However, after metamorphosis, the juvenile is surrounded by self‐tunic cells derived from mesenchymal cell lineages. Both test cells and tunic cells are thought to be changed their distributions during metamorphosis, but the precise timing is unknown.Results: Using a metamorphosis induction by mechanical stimulation, we investigated the dynamics of mesenchymal cells during metamorphosis in a precise time course. After the stimulation, two‐round Ca2+ transients were observed. Migrating mesenchymal cells came out through the epidermis within 10 min after the second phase. We named this event “cell extravasation.” The cell extravasation occurred at the same time as the backward movement of posterior trunk epidermal cells. Timelapse imaging of transgenic‐line larva revealed that non‐self‐test cells and self‐tunic cells temporarily coexist outside the body until the test cells are eliminated. At the juvenile stage, only extravasated self‐tunic cells remained outside the body.Conclusions: We found that mesenchymal cells extravasated following two‐round Ca2+ transients, and distributions of test cells and tunic cells changed in the outer body after tail regression.
Evolutionary history shapes grassland productivity through opposing effects on complementarity and selection
Authors: Larkin Daniel J. , Glasenhardt Mary‐Claire , Williams Evelyn W. , Karimi Nisa , Barak Rebecca S. , Leavens Emma , Hipp Andrew L. 
Published: June 2023

AbstractPhylogenetic diversity (PD), the evolutionary history of the organisms comprising a community, is increasingly recognized as an important driver of ecosystem function. However, biodiversity–ecosystem function experiments have rarely included PD as an a priori treatment. Thus, PD's effects in existing experiments are often confounded by covarying differences in species richness and functional trait diversity (FD). Here we report an experimental demonstration of strong PD effects on grassland primary productivity that are independent of FD, which was separately manipulated, and species richness, which was planted uniformly high to mimic diverse natural grasslands. Partitioning diversity effects demonstrated that higher PD increased complementarity (niche partitioning and/or facilitation) but lowered selection effects (probability of sampling highly productive species). Specifically, for every 5% increase in PD, complementarity increased by 26% on average (±8% SE), while selection effects decreased more modestly (8 ± 16%). PD also shaped productivity through clade‐level effects on functional traits, that is, trait values associated with particular plant families. This clade effect was most pronounced in the Asteraceae (sunflower family), which, in tallgrass prairies, generally comprises tall, high‐biomass species with low phylogenetic distinctiveness. FD also reduced selection effects but did not alter complementarity. Our results show that PD, independent of richness and FD, mediates ecosystem function through contrasting effects on complementarity and selection. This adds to growing evidence that consideration of phylogenetic dimensions of biodiversity can advance ecological understanding and inform conservation and restoration.
ILAE Genetic Literacy Series: Postmortem Genetic Testing in Sudden Unexpected Death in Epilepsy
Authors: Bagnall Richard D. , Perucca Piero ,   for the ILAE Genetics Commission
Published: June 2023

AbstractA 24‐year‐old man with non‐lesional bitemporal lobe epilepsy since age 16 years was found dead in bed around midday. He was last seen the previous night when he was witnessed to have a tonic–clonic seizure. Before his death, he was experiencing weekly focal impaired awareness seizures and up to two focal‐to‐bilateral tonic–clonic seizures each year. He had trialed several antiseizure medications and was on levetiracetam 1500 mg/day, lamotrigine 400 mg/day, and clobazam 10 mg/day at the time of death. Other than epilepsy, his medical history was unremarkable. Of note, he had an older brother with a history of febrile seizures and a paternal first cousin with epilepsy. No cause of death was identified following a comprehensive postmortem investigation. The coroner classified the death as “sudden unexpected death in epilepsy” (SUDEP), and it would qualify as “definite SUDEP” using the current definitions.1 This left the family with many questions unanswered; in particular, they wish to know what caused the death and whether it could happen to other family members. Could postmortem genetic testing identify a cause of death, provide closure to the family, and facilitate cascade genetic testing of first‐degree family members who may be at risk of sudden death? While grieving family members struggle with uncertainty about the cause of death, we as clinicians also face similar uncertainties about genetic contributions to SUDEP, especially when the literature is sparse, and the utility of genetic testing is still being worked out. We aim to shed some light on this topic, highlighting areas where data is emerging but also areas where uncertainty remains, keeping our case in mind as we examine this clinically important area.