bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solution of Homogeneous Linear Fractional Differential Equations Involving Conformable Fractional Derivative
Authors: TYAGI ANUJ , Chandel Jyotsna 
Published: August 2023

In this paper, we have found the solution of linear sequential fractional differential equations involving conformable fractional derivatives of order with constant coefficients. For this purpose, we first discussed fundamental properties of the conformable derivative and then obtained successive conformable derivatives of the fractional exponential function. After this, we determined the analytic solution of linear sequential fractional differential equations (L.S.F.D.E.) in terms of a fractional exponential function. We have demonstrated this developed method with a few examples of homogeneous linear fractional differential equations. This method gives a conjugation with the method to solve classical linear differential equations with constant coefficients.
Fixed Point Theorem for Fuzzy B-type Contractions in Fuzzy Metric Spaces
Authors: Singh Vizender , Singh Bijender , Ahlawat Anil 
Published: August 2023

Recently, in 2021, Bijender et al. proposed the establishment of -contraction. Such sort of contraction is a genuine generalization of the standard contraction in the study of metric fixed point theory. The aim of the present study is the establishment of the novel concept of the fuzzy B-type contraction in the settings of fuzzy metric space and such contractions are also used to establish a few fixed point theorems.
Analysing Moderating Effects of Demographic Variables on Customer Satisfaction: A Study of Quick Service Restaurant
Authors: Shandilya Gautam , Dubey Ajitabh , Srivastava Praveen 
Published: August 2023

Customers' perceptions of service quality are essential for service companies' survival in today’s challenging business environment. While much research has been conducted on service quality, relatively few have examined how demographic variables influence the connection between the quality of service and price on customer satisfaction in the fast-food outlets or what is now known as Quick Service Restaurant (QSR). The present study attempts to gain a deeper insight into the association of Customer Satisfaction (CS) with Service Quality (SQ) and Pricing (value). Simultaneously, the current study also explores how the demographic variables moderate the relationship between the constructs described above.
It is a quantitative research that used a standardized, self-administered online questionnaire and a random sample technique to collect data from 360 customers of QSR in India. SPSS and Smart PLS were used to analyze the data obtained. Smart PLS was used to ascertain the impact of price and SQ on CS and the effect of moderating variables.
The finding suggests that both price and SQ have a positive and significant relation with CS. The demographic variables moderate the relationship between price and customer satisfaction; however, only income moderates the relationship between SQ and CS. These results suggest that restaurant QSR managers/owners should strengthen Service Quality to enhance Customer Satisfaction. Hence, the manager/owner should provide value for money and quality service to their customer to satisfy them.
Misappropriation of Trade Secrets Under the Indian Legal Framework: An Analytical Study
Authors: T. N. Veena 
Published: August 2023

The main purpose of this paper is to examine the aspects of the misappropriation of trade secrets under the Indian legal framework, and how this can be prevented. The paper also tries to understand the nature of trade secrets, the reasons for protecting them, and the practical challenges in identifying and protecting them as there is no legal framework in India to protect trade secrets from misappropriation. The paper concludes by highlighting the challenges to the Indian legal framework, in handling and protecting the misappropriation of trade secrets.
Pathological personality traits from ICD-11 and attachment – Comparison of 10 models of attachment dimensions
Authors: Siczek Anna , Cieciuch Jan 
Published: August 2023

Cel pracyCelem badania była analiza związków między zaburzeniami osobowości w nowym dymensjonalnym ujęciu ICD-11 a przywiązaniem różnie konceptualizowanym w dziesięciu modelach i operacjonalizowanym w siedmiu kwestionariuszach.MetodaBadanie zostało przeprowadzane online i uczestniczyła w nim grupa niekliniczna N = 391 (68% kobiet, 30% mężczyzn i 2% osób które zaznaczyły kategorie ,,inna’’ w wieku od 16 do 65 lat; M = 24,91; SD = 7,8). Przywiązanie mierzone było za pomocą siedmiu kwestionariuszy, a do pomiaru zaburzeń osobowości wykorzystano polską adaptację Kwestionariusza PICD (pomiar zaburzeń osobowości wg ICD-11).WynikiPrzeprowadzona analiza regresji ujawniła spójny obraz związków między przywiązaniem pozabezpiecznym (niezależnie od modelu) a zaburzeniami osobowości. Negatywny Afekt i Rozhamowanie wiążą się z przywiązaniem lękowym a Izolacja oraz Dyssocjalność z unikającym. Anankastyczność wykazała jedynie sporadyczny związek z przywiązaniem.WnioskiPrzywiązanie kształtujące się w dzieciństwie ma istotny związek z występowaniem zaburzeń osobowości u dorosłych. W przeprowadzonym badaniu uzyskano spójny obraz zależności dzięki zastosowaniu wielu konceptualizacji i operacjonalizacji przywiązania.
Neck weakness in individuals with motor neurone disease: an insight into head support
Authors: Sheehy Timothy P , Connors Karol A , Wools Christine A 
Published: August 2023

Background/Aims Neck weakness and head drop can occur in individuals with motor neurone disease, further contributing to disability and lower quality of life. The aims of this study were to explore the characteristics of neck weakness in motor neurone disease and the different types of head support used by patients. Methods A cross-sectional study was performed, where 33 participants with motor neurone disease-related neck weakness answered a 17-item questionnaire. The questions covered their neck weakness and the types of head support they used at the time. Results All participants reported that their quality of life was negatively impacted by their neck weakness. Of the participants, 51.5% reported forward head drop and 42.4% reported that their head dropped both forward and to the side. The most common head support strategy was tilting their chair backwards, followed by the soft neck collar and a rigid collar (Aspen Vista). The majority used either two or three head support strategies in a given day. A total of 26 participants used neck collars, with 11 requiring modifications to their neck collars and 13 reporting not being able to use their neck collar for as long as they wished. Conclusions This study identified the negative impact that neck weakness has on the quality of life for people living with motor neurone disease, and how varied people’s experiences are of living with and attempting to manage this symptom. This is a complex symptom for allied health professionals to manage and an individualised approach is required.
Assessment of progression and clinical relevance of stress-shielding around press-fit radial head arthroplasty
Authors: Giannicola Giuseppe , Amura Andrea , Sessa Pasquale , Prigent Sebastien , Cinotti Gianluca 
Published: August 2023

AimsThe aim of this study was to analyze how proximal radial neck resorption (PRNR) starts and progresses radiologically in two types of press-fit radial head arthroplasties (RHAs), and to investigate its clinical relevance.MethodsA total of 97 patients with RHA were analyzed: 56 received a bipolar RHA (Group 1) while 41 received an anatomical implant (Group 2). Radiographs were performed postoperatively and after three, six, nine, and 12 weeks, six, nine, 12, 18, and 24 months, and annually thereafter. PRNR was measured in all radiographs in the four radial neck quadrants. The Mayo Elbow Performance Score (MEPS), the abbreviated version of the Disabilities of the Arm, Shoulder, and Hand questionnaire (QuickDASH), and the patient-assessed American Shoulder and Elbow Surgeons score - Elbow (pASES-E) were used for the clinical assessment. Radiological signs of implant loosening were investigated.ResultsThe mean follow-up was six years (2 to 14). PRNR started after a mean of 7.5 weeks (SD 2.1) and progressed significantly during the first two years, by the end of which the bone resorption stabilized. PRNR was detected in 81% (n = 45) of patients in Group 1 and 88% (n = 36) in Group 2. The final mean PRNR was 3.0 mm (SD 2.3) in Group 1 and 3.7 mm (SD 2.5) in Group 2. The mean MEPS, QuickDASH, and pASES-E were 95.9 (SD 11.5), 4.4 (SD 9.2), and 94.8 (SD 10.9) in Group 1 and 92.2 (SD 16.2), 9.9 (SD 21.5), and 90.8 (SD 15) in Group 2, respectively. No significant differences were observed between groups in the clinical and radiological outcomes. No correlations were found between PRNR and the clinical results.ConclusionPRNR after press-fit RHA is a common radiological finding that develops in the first 24 months before stabilizing definitively. PRNR does not affect the clinical results or implant survival in the mid term.Cite this article: Bone Joint J 2023;105-B(8):905–911.
Association between additional weekend rehabilitation and in-hospital mortality in patients with hip fractures
Authors: Ogawa Takahisa , Onuma Ryo , Kristensen Morten T. , Yoshii Toshitaka , Fujiwara Takeo , Fushimi Kiyohide , Okawa Atsushi , Jinno Tetsuya 
Published: August 2023

AimsThe aim of this study was to investigate the association between additional rehabilitation at the weekend, and in-hospital mortality and complications in patients with hip fracture who underwent surgery.MethodsA retrospective cohort study was conducted in Japan using a nationwide multicentre database from April 2010 to March 2018, including 572,181 patients who had received hip fracture surgery. Propensity score matching was performed to compare patients who received additional weekend rehabilitation at the weekend in addition to rehabilitation on weekdays after the surgery (plus-weekends group), as well as those who did not receive additional rehabilitation at the weekend but did receive weekday rehabilitation (weekdays-only group). After the propensity score matching of 259,168 cases, in-hospital mortality as the primary outcome and systemic and surgical complications as the secondary outcomes were compared between the two groups.ResultsThe plus-weekends group was significantly associated with lower in-hospital mortality rates compared with the weekdays-only group (hazard ratio 0.86; 95% confidence interval 0.8 to 0.92; p < 0.001). Systemic complications such as acute coronary syndrome, heart failure, renal failure, and sepsis were significantly lower in the plus-weekends group, whereas urinary tract infection (UTI) and surgical complications such as surgical site infection and haematoma were significantly higher in the plus-weekends group.ConclusionAdditional weekend rehabilitation was significantly associated with lower in-hospital mortality, as well as acute coronary syndrome, heart failure, renal failure, and sepsis, but was also significantly associated with a higher risk of UTI and surgical complications. This result can facilitate the effective use of the limited rehabilitation resources at the weekend and improve the clinical awareness of specific complications. To establish more robust causal associations between additional rehabilitation over the weekend and clinical outcomes, further prospective studies or randomized controlled trials with larger sample sizes are warranted.Cite this article: Bone Joint J 2023;105-B(8):872–879.
Outcomes in Ankle Replacement Study (OARS)
Authors: Smith Toby O. , Dainty Jack , Loveday David T. , Toms Andoni , Goldberg Andrew J. , Watts Laura , Pennington Mark W. , Dawson Jill , van der Meulen Jan , MacGregor Alexander J. 
Published: August 2023

AimsThe aim of this study was to capture 12-month outcomes from a representative multicentre cohort of patients undergoing total ankle arthroplasty (TAA), describe the pattern of patient-reported outcome measures (PROMs) at 12 months, and identify predictors of these outcome measures.MethodsPatients listed for a primary TAA at 19 NHS hospitals between February 2016 and October 2017 were eligible. PROMs data were collected preoperatively and at six and 12 months including: Manchester-Oxford Foot and Ankle Questionnaire (MOXFQ (foot and ankle)) and the EuroQol five-dimension five-level questionnaire (EQ-5D-5L). Radiological pre- and postoperative data included Kellgren-Lawrence score and implant position measurement. This was supplemented by data from the National Joint Registry through record linkage to determine: American Society of Anesthesiologists (ASA) grade at index procedure; indication for surgery, index ankle previous fracture; tibial hind foot alignment; additional surgery at the time of TAA; and implant type. Multivariate regression models assessed outcomes, and the relationship between MOXFQ and EQ-5D-5L outcomes, with patient characteristics.ResultsData from 238 patients were analyzed. There were significant improvements in MOXFQ and EQ-5D-5L among people who underwent TAA at six- and 12-month assessments compared with preoperative scores (p < 0.001). Most improvement occurred between preoperative and six months, with little further improvement at 12 months. A greater improvement in MOXFQ outcome postoperatively was associated with older age and more advanced radiological signs of ankle osteoarthritis at baseline.ConclusionTAA significantly benefits patients with end-stage ankle disease. The lack of substantial further overall change between six and 12 months suggests that capturing PROMs at six months is sufficient to assess the success of the procedure. Older patients and those with advanced radiological disease had the greater gains. These outcome predictors can be used to counsel younger patients and those with earlier ankle disease on the expectations of TAA.Cite this article: Bone Joint J 2023;105-B(8):895–904.
A prospective radiostereometric analysis of the stability of a metal-backed glenoid component/autograft composite in reverse shoulder arthroplasty
Authors: Cunningham Lindsay J. , Walton Mike , Bale Steve , Trail Ian A. 
Published: August 2023

AimsReverse total shoulder arthroplasty (rTSA) can be used in complex cases when the glenoid requires reconstruction. In this study, a baseplate with composite bone autograft and a central trabecular titanium peg was implanted, and its migration was assessed for two years postoperatively using radiostereometric analysis (RSA).MethodsA total of 14 patients who underwent a rTSA with an autograft consented to participate. Of these, 11 had a primary rTSA using humeral head autograft and three had a revision rTSA with autograft harvested from the iliac crest. The mean age of the patients was 66 years (39 to 81). Tantalum beads were implanted in the scapula around the glenoid. RSA imaging (stereographic radiographs) was undertaken immediately postoperatively and at three, six, 12, and 24 months. Analysis was completed using model-based RSA software. Outcomes were collected preoperatively and at two years postoperatively, including the Oxford Shoulder Score, the American Shoulder and Elbow Score, and a visual analogue score for pain. A Constant score was also obtained for the assessment of strength and range of motion.ResultsRSA analysis showed a small increase in all translation and rotational values up to six months postoperatively, consistent with settling of the implant. The mean values plateaued by 12 months, with no evidence of further migration. In four patients, there was significant variation outside the mean, which corresponded to postoperative complications. There was a significant improvement in the clinical and patient-reported outcomes from the preoperative values to those at two years postoperatively (p < 0.001).ConclusionThese findings show, using RSA, that a glenoid baseplate composite of a trabecular titanium peg with autograft stabilizes within the glenoid about 12 months after surgery, and reinforce findings from a previous study of this implant/graft with CT scans at two years postoperatively, indicating that this type of structural composite results in sound early fixation.Cite this article: Bone Joint J 2023;105-B(8):912–919.
The association between lead exposure and crime: A systematic review
Authors: Talayero Maria Jose , Robbins C. Rebecca , Smith Emily R. , Santos-Burgoa Carlos 
Published: August 2023

Prior research has demonstrated an association between lead exposure and criminal behavior at the population-level, however studies exploring the effect of lead exposure on criminal behavior at the individual-level have not been reviewed systematically. The intent of this study is to complete a systematic review of all studies assessing individual-level exposures to lead and the outcomes of crime and antisocial behavior traits. We included peer reviewed studies that were published prior to August 2022 and were classified as cohort, cross-sectional, or case-control. Studies measuring the outcomes of crime, delinquency, violence, or aggression were included. The following databases were searched using a standardized search strategy: ProQuest Environmental Science Database, PubMed, ToxNet and the Public Affairs Information Service (PAIS). Seventeen manuscripts met our inclusion criteria. Blood lead was measured in 12 studies, bone lead in 3 studies, and dentine lead levels in 2 studies. This systematic review identified a wide range of diverse outcomes between exposure to lead at multiple windows of development and later delinquent, criminal and antisocial behavior. A review of all potential confounding variables included within each study was made, with inclusion of relevant confounders into the risk of bias tool. There is limited data at the individual level on the effects of prenatal, childhood, and adolescent lead exposure and later criminal behavior and more evidence is necessary to evaluate the magnitude of the associations seen in this review. Our review, in conjunction with the available biological evidence, suggests that an excess risk for criminal behavior in adulthood exists when an individual is exposed to lead in utero or in the early years of childhood. The authors report no conflict of interest and no funding source.
Clinical trial registration: PROSPERO ID: CRD42021268379.
Development of ankylosing spondylitis in patients with ulcerative colitis: A systematic meta-analysis
Authors: Lin Aitao , Tan Yongyi , Chen Jinxia , Liu Xiaoyu , Wu Jinyu 
Published: August 2023

Background
Ulcerative colitis (UC) is a manifestation of inflammatory bowel disease (IBD), which can cause inflammation of the intestinal tract. Ankylosing spondylitis (AS) is an inflammatory disease of the sacroiliac joints. Many studies have found that some UC patients progress to AS. In this study, we conducted a literature search and meta-analysis to investigate the prevalence of AS among UC patients during follow-up.

Methods
The studies related to the AS among patients with UC were obtained from PubMed, Web of Science, Embase, and Cochrane Library databases since its inception-December 2022. The literature was screened strictly according to inclusion and exclusion criteria. Forest plots were used to detect the overall incidence of AS in UC and to compare the risk ratios for the development of AS in the UC. The heterogeneity of studies was assessed using I2 statistical methods.

Results
1) 17 studies with 98704 UC patients were included. 2)700 UC patients developed AS during follow-up (1.66%, 95% CI: 0.89–2.62%). Human leukocyte antigen B27 (HLA-B27) was reported in 3 studies. HLA-B27 positivity was significantly higher than the incidence of HLA-B27 negativity in AS patients (68.29% vs 31.71%, P < 0.0001). There was significantly increased risk of AS development in HLA-B27 positive IBD patients (RR: 22.17, 95% CI: 11.79–41.66, P < 0.0001). 3)The definite follow-up time was reported in 12 studies (range: 0.3–40 years). After follow-up for ≥5 years, the incidence of AS among patients with UC was 1.75% (95% CI: 0.62–3.37%). Meanwhile, after follow-up for <5 years, the incidence of AS among patients with UC was 1.41% (95% CI: 0.65–2.37%) which was significant.

Conclusion
Patients with UC are more likely to develop AS in the future. Furthermore, the IBD patients are at a higher risk of AS who have positive HLA-B27. The incidence of AS increased with longer follow-up time.
Biochemical phenotyping of paroxysmal nocturnal hemoglobinuria reveals solute carriers and β-oxidation deficiencies
Authors: Yamakawa Patricia Eiko , Fonseca Ana Rita , Guerreiro da Silva Ismael Dale Cotrim , Gonçalves Matheus Vescovi , Marchioni Dirce Maria , Carioca Antonio Augusto Ferreira , Michonneau David , Arrais-Rodrigues Celso 
Published: August 2023

Introduction
Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal disease of hematopoietic cells with a variable clinical spectrum characterized by intravascular hemolysis, high risk of thrombosis, and cytopenias. To understand the biochemical shifts underlying PNH, this study aimed to search for the dysfunctional pathways involved in PNH physiopathology by comparing the systemic metabolic profiles of affected patients to healthy controls and the metabolomic profiles before and after the administration of eculizumab in PNH patients undergoing treatment.

Methods
Plasma metabolic profiles, comprising 186 specific annotated metabolites, were quantified using targeted quantitative electrospray ionization tandem mass spectrometry in 23 PNH patients and 166 population-based controls. In addition, samples from 12 PNH patients on regular eculizumab maintenance therapy collected before and 24 hours after eculizumab infusion were also analyzed.

Results
In the PNH group, levels of the long-chain acylcarnitines metabolites were significantly higher as compared to the controls, while levels of histidine, taurine, glutamate, glutamine, aspartate and phosphatidylcholines were significantly lower in the PNH group. These differences suggest altered acylcarnitine balance, reduction in the amino acids participating in the glycogenesis pathway and impaired glutaminolysis. In 12 PNH patients who were receiving regular eculizumab therapy, the concentrations of acylcarnitine C6:1, the C14:1/C6 ratio (reflecting the impaired action of the medium-chain acyl-Co A dehydrogenase), and the C4/C6 ratio (reflecting the impaired action of short-chain acyl-Co A dehydrogenase) were significantly reduced immediately before eculizumab infusion, revealing impairments in the Acyl CoA metabolism, and reached levels similar to those in the healthy controls 24 hours after infusion.

Conclusions
We demonstrated significant differences in the metabolomes of the PNH patients compared to healthy controls. Eculizumab infusion seemed to improve deficiencies in the acyl CoA metabolism and may have a role in the mitochondrial oxidative process of long and medium-chain fatty acids, reducing oxidative stress, and inflammation.