bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nationwide representative serosurvey of third-grade school children to evaluate the hepatitis B vaccination impact in Kyrgyzstan, 2022
Authors: Brandl Michael , Zhumagulova Gulnara , Ishenapysova Gulbara , Nurmatov Zuridin , Kuchuk Tatiana Enverovna , Zamirbekova Nurzhan , Sattarova Gulsunai , Temirbekova Saikal , Bekenova Zhanara , Gassowski Martyna , Mosina Liudmila , Mozalevskis Antons , Dudareva Sandra , Datta Siddhartha Sankar 
Published: January 2025

Abstract

Background
Kyrgyzstan introduced universal hepatitis B childhood vaccination in 1999 to reduce the burden of hepatitis B. In 2016, aligned with the goal of controlling hepatitis B in the WHO European Region, a regional target of 0.5% was set for seroprevalence of hepatitis B surface antigen (HBsAg) among targeted birth cohorts. We conducted a representative nationwide serosurvey to assess the HBsAg prevalence among third-grade school children in Kyrgyzstan in 2022.

Methods
We sampled numbers of children proportional to the population size and stratified the sample by region and urbanization level (urban/rural). We applied multistage cluster sampling with school classes as clusters. Identified participants in the survey were tested for HBsAg, using Enzyme-linked Immunosorbent Assay (ELISA), and positive samples confirmed with neutralization tests. Data on vaccination coverage for hepatitis B birth dose (HepB BD), including timing, and three doses of hepatitis B vaccine (HepB3) were collected from medical vaccination records. We calculated crude and weighted proportions for HBsAg seroprevalence and HepB BD and HepB3 coverage.

Results
From the target sample size of 3,352 children, a total of 3,183 children (95%) participated in the survey. The majority of children were 9 or 10 years old (2,964; 93%) with almost equal numbers of girls and boys (1,606; 50% boys) and rural and urban participants (1,624; 51% urban). Five participants tested positive for HBsAg in confirmatory tests. The weighted HBsAg seroprevalence was 0.12% (95% CI 0.04–0.35%). Weighted coverage for HepB BD was 88% (95% CI 86–90%) and for HepB3 90% (95% CI 86–93%). Results from crude and weighted analysis did not differ statistically.

Conclusions
Our study demonstrates the impact of a successfully implemented hepatitis B vaccination programme in Kyrgyzstan. High hepatitis B vaccination coverage has resulted in very low HBsAg seroprevalence among vaccinated birth cohorts, paving the way towards the achievement of regional hepatitis B control targets. Maintaining high vaccination uptake plus additional measures like screening of pregnant women and treatment of those infected will be key to achieve elimination of vertical transmission of hepatitis B in Kyrgyzstan.
An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy
Authors: Hammer Maximilian , Ie Amanda , Eibenberger Katharina , Auffarth Gerd Uwe , Xue Kanmin 
Published: January 2025

Abstract

Purpose
Proliferative vitreoretinopathy (PVR) is a complication of retinal detachment which requires multiple vitreoretinal surgical interventions and frequent use of oil endotamponade. In this study, we conducted an in-depth analysis of complications associated with the use of heavy silicone oil in the management of inferior PVR.

Methods
A retrospective cohort study of 20 eyes that underwent vitrectomy for inferior PVR with use of heavy silicone oil (Densiron 68) between March 2021 and October 2022 at Oxford Eye Hospital. Complications were classified into major categories relating to intraocular pressure, inflammation, lens, and oil emulsification/migration. Visual outcomes and surgical success rate were also evaluated.

Results
Fill-induced pressure spikes (> 30 mmHg) within 14 days post-surgery were common after Densiron tamponade, especially in patients previously on glaucoma drops. The number of glaucoma drugs were increased in 45% of patients during Densiron tamponade. In 20% of cases, an increased medication was continued long-term after Densiron removal. Significant cataract progression occurred in all phakic patients. In 25% of pseudophakic cases, posterior capsule opacification was noted. Inflammatory complications, such as anterior uveitis, were rare and any cystoid macular oedema was transient. No unexplained acute loss of vision following Densiron removal was encountered. The anatomical success rate at 30 days after Densiron removal was 70%. The mean (± SD) best-corrected visual acuities were 1.04 (± 0.79), 0.85 (± 0.62) and 0.50 (± 0.51) logMAR prior, during and after Densiron tamponade, respectively.

Conclusion
The outcomes in this cohort treated with Densiron 68 were comparable to previously reported anatomical and functional results in cases with inferior PVR. IOP and lens-related complications require additional treatment during or after Densiron tamponade. Inflammatory complications rarely occurred over tamponade durations of around three months.

Trial registration
Analyses were conducted as an internal quality improvement audit and as such did not require external IRB review.
A single-site randomized controlled trial of partner navigation to HCV treatment for people who inject drugs: a study protocol for the You’re Empowered for Treatment Initiation (YETI) partner trial
Authors: Morris Meghan D. , Tan Judy Y. , McDonell Claire C. , Scarpetta Maia , Nguyen Tiffany N. , Price Jennifer C. , Neilands Torsten B. 
Published: January 2025

Abstract

Background
Disparities persist in testing and treatment for hepatitis C virus (HCV), leaving socially marginalized populations, including people who inject drugs (PWID), less likely to benefit from curative treatment. Linkage services are often insufficient to overcome barriers to navigating the medical system and contextual factors.

Methods
The You’re Empowered for Treatment Initiation (YETI) Partner trial is a single-site randomized controlled trial evaluating the efficacy of a two-session behavioral intervention that engages injecting partners as peer navigators for HCV treatment. We aim to recruit 250 PWID and their primary injecting partners in San Francisco, California, randomizing them 1:1 to either a control or intervention group. The primary outcome is the initiation of HCV treatment, with secondary outcomes including treatment completion and sustained virologic response 12 weeks post-treatment. Data will be collected through questionnaires and electronic health records and analyzed using intention-to-treat and mixed-effects models.

Discussion
This trial will provide evidence of a new HCV treatment linkage intervention leveraging the support of primary injecting partners to initiate HCV treatment. If successful, the intervention could inform public health strategies and policies to address HCV in marginalized populations.

Trial registration
ClinicalTrials.gov NCT06179498. Registered on December 22, 2023.
Internalizing and externalizing symptoms in individuals with neurofibromatosis type 1: a systematic review and meta-analysis
Authors: Liu Dan , Yu Liyan , Wu Xian , Moreira Julia , Mujica Benjamin Felipe , Mukhopadhyay Elora Shelly , Novotney Angelena , Rietman André B. , Hou Yang 
Published: January 2025

Abstract

Background
Individuals with neurofibromatosis type 1 (NF1) frequently report psychosocial problems, among which internalizing and externalizing symptoms are the most poorly understood due to limited research and inconsistent evidence. This hinders the overall attendance of their psychosocial needs and has a major impact on their quality of life. Thus, this systematic review and meta-analysis was conducted to synthesize existing findings on the degree to which individuals with NF1 experience internalizing and externalizing symptoms, compared with the unaffected population, and explore moderators of the group disparities.

Methods
Scopus, PsycINFO, Web of Science, PubMed, and ProQuest were searched from inception to March 26th, 2024, which identified 59 eligible studies (N of NF1 = 3182, mean ages 2.38 to 46.4 years). Hedges’ g was calculated for differences in internalizing and externalizing symptoms between the NF1 group and the unaffected controls. Study effect sizes were pooled using robust variance estimation and random-effects models. Moderators of group differences were tested using meta-regression.

Results
Random-effects meta-analyses indicated that compared with unaffected controls, individuals with NF1 showed more severe depressive (k = 21; g = 0.43; 95% CI [0.21, 0.65]), anxiety (k = 24; g = 0.27; 95% CI [0.01, 0.54]), somatic (k = 27; g = 0.56; 95% CI [0.30, 0.83]), total internalizing (k = 75; g = 0.50; 95% CI [0.33, 0.67]), aggression (k = 33; g = 0.33; 95% CI [0.08, 0.58]), delinquency, (k = 37; g = 0.43; 95% CI [0.26, 0.60]), and total externalizing symptoms (k = 47; g = 0.24; 95% CI [0.13, 0.35]). Studies that included more participants with NF1 who had ADHD or a lower verbal IQ reported greater group disparities in total internalizing symptoms or aggression.

Conclusions
Findings highlight the importance of promptly recognizing internalizing and externalizing symptoms in individuals with NF1 for timely interventions. Future research should identify predictors of internalizing and externalizing symptoms within the NF1 population to inform our knowledge and intervention development. Other implications for future research were also discussed.

Systematic review registration
The study protocol of this meta-analysis was registered at PROSPERO (CRD42023478258).
Using Optimization Techniques on Mechanical Characteristics and Sustainability Assessment of Rubberized Concrete Blended with PVA Fiber Through Response Surface Methodology
Authors: Bheel Naraindas , Baikerikar Abhijeet Vidyadhar , Mohammed Bashar S. 
Published: January 2025

Abstract
The construction sector is promoting eco-friendly materials to combat global warming. Researchers use crumb rubber (CR) in concrete due to its ductility and hardness, but studies show it can decrease strength. Therefore, the addition of PVA fiber improves the mechanical properties of CR concrete. The research aims to assess the mechanical and physical characteristics of concrete by utilizing RSM modeling and optimization, comparing the effects of CR replacement for sand and PVA fiber by volume fraction. It has been observed that the optimum compressive, tensile and flexural strengths were observed by 49 MPa, 4.31 MPa, and 5.88 MPa at 10% of sand replaced with CR and 1.5% of PVA fiber together at 28 days, respectively. In addition, water absorption improves with increased CR and PVA fiber in concrete, while dry density decreases with increased CR and PVA fiber quantity in concrete at 28 days, respectively. Moreover, RSM was utilized to develop response prediction models with R2 coefficients ranged from 97 to 99%. Furthermore, the enhancement of embodied carbon is seen when the volume percent of PVA fiber and CR increases in concrete. Additionally, using 10% CR instead of sand and adding 1.5% PVA fiber has been proven to deliver favourable outcomes for the construction sector therefore it is recommended for construction purpose.
Semaglutide, type 2 diabetes, and the risk of nonarteritic anterior ischemic optic neuropathy
Authors: Malerbi Fernando K. , Bertoluci Marcello C. 
Published: January 2025

Abstract
In the last months, conflicting evidence on a possible association between the use of semaglutide and incident nonarteritic anterior ischemic optic neuropathy (NAION) has emerged. A recently published study, which evaluated all patients with type 2 diabetes in Denmark, has shown with robustness that once-weekly semaglutide doubles the five-year risk of NAION. In this comment, the new evidence is discussed, along with practical implications for type 2 diabetes patients. The possibility of ophthalmological evaluation regarding optic disc morphology is suggested, before initiation of semaglutide treatment or, for those patients already under treatment, during a follow-up ophthalmological visit. If a disc-at-risk pattern is detected, such information could be brought to the attention of the attending clinician involved with diabetes control and discussed with patients for a shared decision-making approach. A new risk-benefit discussion weighing the undoubted benefits of semaglutide in reducing cardiovascular mortality and cardiovascular events, heart failure hospitalization, and renal protection must be started and carefully balanced against a rare but devastating condition such as NAION.
Burden of depressive and anxiety disorders in China and its provinces, 1990–2021: findings from the Global Burden of Disease Study 2021
Authors: Tian Wei , Yan Guangcan , Xiong Shangzhi , Zhang Jing , Peng Junyi , Zhang Xinyi , Zhou Yuanzhong , Liu Tao , Zhang Yafeng , Ye Pengpeng , Zhao Wenran , Tian Maoyi 
Published: January 2025

Background
Depressive and anxiety disorders constitute a major component of the disease burden of mental disorders in China.

Aims
To comprehensively evaluate the disease burden of depressive and anxiety disorders in China.

Method
The raw data is sourced from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. This study presented the disease burden by prevalence and disability-adjusted life years (DALYs) of depressive and anxiety disorders at both the national and provincial levels in China from 1990 to 2021, and by gender (referred to as 'sex' in the GBD 2021) and age.

Results
From 1990 to 2021, the number of depressive disorder cases (from 34.4 to 53.1 million) and anxiety disorders (from 40.5 to 53.1 million) increased by 54% (95% uncertainty intervals: 43.9, 65.3) and 31.2% (19.9, 43.8), respectively. The age-standardised prevalence rate of depressive disorders decreased by 6.4% (2.9, 10.4), from 3071.8 to 2875.7 per 100 000 persons, while the prevalence of anxiety disorders remained stable. COVID-19 had a significant adverse impact on both conditions. There was considerable variability in the disease burden across genders, age groups, provinces and temporal trends. DALYs showed similar patterns.

Conclusion
The burden of depressive and anxiety disorders in China has been rising over the past three decades, with a larger increase during COVID-19. There is notable variability in disease burden across genders, age groups and provinces, which are important factors for the government and policymakers when developing intervention strategies. Additionally, the government and health authorities should consider the potential impact of public health emergencies on the burden of depressive and anxiety disorders in future efforts.
Investigating the associations between personality functioning, cognitive biases, and (non-)perceptive clinical high-risk symptoms of psychosis in the community
Authors: Rinaldi Giulia , Lerch Stefan , Schultze-Lutter Frauke , Schmidt Stefanie Julia , Cavelti Marialuisa , Kaess Michael , Michel Chantal 
Published: January 2025

Abstract

Background
Beyond psychosis prediction, clinical high-risk (CHR-P) symptoms show clinical relevance by their association with functional impairments and psychopathology, including personality pathology. Impaired personality functioning is prioritized in recent dimensional personality disorder models (DSM-5, ICD-11), yet underexplored in CHR-P, as are associations with cognitive biases, which early studies indicate as possibly linking CHR-P-symptoms and personality pathology.

Methods
A community sample (N = 444, 17–60 years, 61.8% female) was assessed via clinical telephone interview and online questionnaires. Using zero-inflated Poisson models, we explored associations of personality functioning, cognitive biases, current psychopathology, and psychosocial functioning with likelihood and severity of overall CHR-P, as well as perceptive (per-) and non-perceptive (nonper-)CHR-P-symptoms distinctly.

Results
Higher nonper-CHR-P-symptom likelihood was associated with more impaired personality functioning and psychosocial functioning, while more severe cognitive biases were associated with higher CHR-P- and per-CHR-P-symptom likelihood, alongside higher CHR-P- and nonper-CHR-P-symptom severity. Further, more axis-I diagnoses were linked to higher CHR-P-, per-CHR-P-, and nonper-CHR-P-symptom likelihood, and younger age to higher CHR-P- and per-CHR-P-symptom severity, with CHR-P-symptom severity appearing higher in females. In an exploratory analysis, personality functioning elements identity and self-direction, and cognitive biases dichotomous thinking, emotional reasoning, and catastrophizing, respectively, showed multifaceted associations with nonper-CHR-P-symptom likelihood and overall CHR-P-symptom expression.

Conclusions
Our study supports the association of CHR-P-symptoms with multiple mental health factors. Findings suggest intricate associations between personality functioning impairments and cognitive biases with CHR-P-symptom expression in non-help-seeking populations, possibly contributing to different per-CHR-P- and nonper-CHR-P-symptom expression patterns. Therefore, they should be targeted in future longitudinal studies, aiming at better understanding CHR-P-manifestations to inform preventive intervention.
It Is You and Allah
Authors: Alkorani Joud 
Published: January 2025

Abstract
This article examines how Muslim women living in Dubai are invited into a distinct relationship with God. Highlighting the role of God in constituting the self, it complicates narratives of self-making that presume a bounded and agentive self, as seen in prior accounts of Islamic piety and neoliberal subjectivity. Through the accounts of women attending Al-Noor Islamic Center, the centrality of God to self-making—“Godly self-making”—becomes apparent. It is by way of God that women make sense of their own selves and interactions with others—and by way of others that they make sense of God. This Godly self-making is entrenched within the circumstances in which it transpires, shaped by Dubai's present-day socioeconomic and political dynamics. As a result, it is premised upon three elements: 1) a personal connection with God; 2) a pious self produced through continuous divine tests; and 3) an emphasis on tawakkul (reliance) upon God. In all three elements, the agency, role, and responsibility of other humans and institutions in shaping one's world are backgrounded, obscuring the politics inherent to divine-human relations and the power struggles that suffuse such exchanges.
Recovering a Hindu Tradition
Authors: Gandhi Supriya 
Published: January 2025

Abstract
Around 1867, North Indian religious reformer Kanhaiyalal Alakhdhari completed a translation into Urdu of fifty-two Upanishads. Alakhdhari, who later played a key role in establishing the Arya Samaj in the Punjab, wished for Hindus to emulate Christians and Muslims in giving centrality to their sacred texts. His translation was based on the Persian Sirr-i akbar produced by the Mughal prince Dara Shukoh (d. 1659), who had claimed that the Upanishads held the key to the Quran's mysteries. How did this imperial project of translation infused with an Islamic interpretive framework come to inform a Hindu revivalist project in the nineteenth century? Through examining Alakhdhari's career and writings, this article explores the entangled histories of Mughal Indology and colonial-era public Hinduism. Alakhdhari's oeuvre illuminates overlooked strands of the genealogy of modern Hinduism: namely, the production of Persian Indological writings during Mughal as well as colonial rule, and the emergence of an Urdu public sphere for Hindus of nineteenth-century North India, especially in the Punjab.
Schisms in the History of Hindu Law
Authors: Srikantan Geetanjali 
Published: January 2025

Abstract
It has been well documented that the marriage, inheritance, and succession laws of Hindus as a religious community in India are a product of British colonial intervention and engagement with Sanskritic legal traditions. However, what has been relatively ignored are the writings and the views of colonial administrator James Henry Nelson on the lack of a Brahmanical Hindu law in the Madras Presidency. Nelson's controversial viewpoints brought him into confrontation with Justice Lewis Charles Innes, a Madras High Court judge. The elements of this confrontation lays bare the fractured nature of Hindu law and its dependence on colonial legal conceptions. This article sheds light on the jurisprudential basis of this debate and concludes by looking at the consequences for Hindu law as a legal entity.
Out of the Ground
Authors: Saleh Elizabeth 
Published: January 2025

Abstract
This article thinks ethnographically with phylloxera, an insect with a lethal proclivity for Vitis vinifera. The infamous louse traveled from North America to Eurasia during the nineteenth century. Fatefully, this tiny bug's journey to Lebanon overlapped with the Jesuit Return Mission to the Orient, which began in 1831. Around 1882, Jesuits successfully imported “French” grape vines that would eventually displace local varieties as well as the bodies of knowledge and taxonomies about them. The tiny bug, barely visible to the naked eye, crept into Jesuit correspondence about these plantations. Creepy-crawly feelings of phylloxera also plagued the oral histories and conversations of residents across the Bekaa Valley that the author documented during fieldwork between 2006 and 2008. By examining these entwined disjointed feelings forged over generations, the article explores how humans and bugs appeared to one another as they sensed dislocating worlds that surfaced in the political afterlife of colonialism. By doing so, it traces the seemingly incorporeal legacy of the Jesuits across Lebanon's viniculture landscape to a colonial logic aimed at generating life in terms of its properties.
The Formation of a Waliullahi Public in Eighteenth-Century India
Authors: Morgan Daniel Jacobius 
Published: January 2025

Abstract
Shah Waliullah of Delhi, the famous eighteenth-century Naqshbandi, is widely recognized as a major figure in the emergence of Islamic reformist discourse in South Asia, but we still have little sense of the first audiences who engaged with his ideas. This article seeks to further our understanding of the crystallization of this reform-oriented Waliullahi public by recreating the fragmentary biography of his lifelong companion and disciple Nurullah Budhanwi. While he didn't write any books that survive, accounts of Nurullah's life and reports of his oral statements are scattered throughout texts produced by Waliullah's circle, and provide insight into the conflicting intellectual, ethical, and affective responses to Waliullah's thought in his own lifetime. This article demonstrates that Nurullah felt deep concern about what his acceptance of Waliullahi reformist ideas might mean for his material and spiritual life, suggesting that the formation of this new reform-oriented public was a fraught process entailing contestation and negotiation. Nurullah's biography shows us that intellectual histories that rely on discussions of abstract ideas of famous thinkers or the simplistic reconstruction of scholarly networks fail to do justice to the complex life of ideas in the world.
Afterword
Authors: Moll Yasmin 
Published: January 2025

Abstract
How should we understand the complex and often contradictory role the other-and-more-than-human occupies in the lives and imaginations of people in the Middle East? Adopting a self-consciously post-secular stance on this question, the contributors of this special section convincingly show the theoretical and narrative possibilities of methodological attunement to the other-worldly and transcendent, to the divine. As I finished reading the section, I was struck by how the ethnographic task of reckoning with God seemed to end up meaning mostly reckoning with theology, with people talking about God. But if to take God seriously anthropologically is above all to pay attention to how our interlocutors themselves take God seriously as they grapple with the range of social, political and economic forces shaping their lives, where does that leave the issue's broader aim of going beyond an anthropocentric anthropology?