bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Wound Healing Activity of Polyherbal Skin Care Cream
Authors: Dwivedi Abhinay Kumar , Sharma Hemant Kumar 
Published: December 2022

Plants have long history of use to cure and prevention of various human ailments. In the present study Azadirachta indica, Ocimum sanctum, Centella asiatica and Hibiscus rosa sinensis extracts have been used to formulate skin care cream with varied proportion of individual extract. The formulations F3 and F4 have been selected for evaluation of wound healing study on the basis of preliminary evaluation results of parameter evaluated for Polyherbal cream. The formulation F3 and F4 were compared with negative control and standard treated group. It was found that the formulation F4 has greater wound contraction and efficiently reduced the time of epithelization campared to negative control with significant level P<0.050 and P>0.001, results indicated that the formulation F4 could be used as effective agent in wound healing.
Keywords: Herbal cream, Wound healing, Flavonoids, Phytochemical
Impact of IVIG in the Management of Guillain-Barre Syndrome: A Case Series from South India
Authors: Singh Daniel Sundar , Harshidha D , Divya T , Ektha Promoth Kumar , Dinesh Kumar G , Dinesh T 
Published: December 2022

In Guillain-Barré syndrome, the body's immune system attacks part of the peripheral nervous system. We present a case series of four cases with different variants. Three cases have been diagnosed with nerve conduction studies, one case with positive lumbar puncture test with albumino-cytological dissociation. Each patient was treated with Intravenous Immunoglobulin (IVIG) and improved clinically. This series is being delivered in order to clinically inform individuals on the early diagnosis of GBS and its management.
Keywords: GBS, IVIG, Lower limb, Lumbar puncture test, Nerve conduction studies, Radiating pain.
Curso de pedagogia a distância
Authors: Lopes Yuna Lélis Beleza , Rivas Noeli Prestes Padilha , Pedroso Cristina Cinto Araújo 
Published: December 2022

Organizado como um ensaio, este artigo tem como objetivo analisar implicações da educação a distância (EaD) na formação de pedagogos, tendo como referência as políticas oficiais. Se situa na linha de pesquisa “Políticas Curriculares para a formação de professores: Educação Superior e Cursos de Licenciatura”. A discussão se desenvolve fundamentada na perspectiva dialética-histórica, contextualizada e situada, entendendo que as contradições se explicitam no movimento histórico. O estudo de natureza bibliográfica tem como principais objetos de análise as concepções, teorias e normativas que na atualidade regulam os cursos de Pedagogia propostos na modalidade a distância. A análise desse material evidencia o jogo das forças que atuam no tecido social que está condicionado pelos contextos econômico, social, cultural e político. Além disso, mostra que o discurso de democratização do acesso ao ensino superior tem fortalecido as políticas públicas alinhadas à educação a distância sem que ocorra, no entanto, o debate das contradições e das suas implicações para a qualidade da formação dos professores e da educação. Assim, este texto debate as reverberações e desdobramentos da formação inicial do pedagogo/professor a distância, com o intuito de desmistificar a ideia de que essa modalidade promove a democratização do ensino superior para as camadas populares tendo em vista seu processo laboral.
Prurigo Reduces Propofol Requirement under General Anesthesia
Authors: Yorulmaz İlknur Suidiye , Ersoy Karka Özlem 
Published: December 2022

Studies, including fMRI, show that neurodegeneration or a decrease in neuron count occurs in certain brain regions of patients with chronic itchy lesions. In these studies attention was also drawn to increased GABAA receptor sensitivity.

In 3 patients suffering from chronic stress-induced non-histaminergic pruritus for more than 6 weeks, who underwent elective orthopedic surgery under total intravenous general anesthesia with bispectral index monitoring, it has been determined that total propofol consumption was 50, 78 and 58 micrograms/kg/min respectively. All three operations lasted more than 2 hours, were completed without any complications or awareness and all 3 patients were hemodynamically stable among the operation. From this point of view, we observed that GABA receptor sensitivity increased in patients with chronic itching. Also the need for propofol during general anesthesia, which acts on GABA receptors, decreased to doses equivalent to average sedation doses. We consider that administering drugs acting on these receptors at optimum doses (using EEG-based monitoring) is important for patient safety especially in patients with chronic itching.
Five Methods of Quran Memorization in Tahfidz House of Fastabiqul Khairat Indonesia
Authors: Engkizar Engkizar , Sarianti Yulia , Namira Silva , Budiman Setria , Susanti Hendra , Albizar Albizar 
Published: December 2022

Degradation of morals or moral decadence has attacked young generations, especially college students. Therefore, this paper aims to find out forms of moral decadence found in college students. This research uses a qualitative method with a case study approach, the data were collected through direct interviews with ten informants (college students) by using the purposive sampling technique. To strengthen interview data, the writer performed passive participation observation by coming directly to the observed location. All results of the interview were analyzed using Milles and Hauberman’s pattern. The research found nine forms of moral decadence in college students. They are: i) negligent in worship, ii)sexual promiscuity, iii) involved in drug abuse, iv) hedonism, v) revealing awrah, vi) lack of ethics, vii) impolite speaking, viii) dishonest in academics and ix) lack of time management. The results of this research can be used as initial data for future research investigating similar problems in different contexts and issues.
The effect of blade density variation to cocopeat mass that produce by Poltesa cocopeat machine
Authors: Santoso Pande Putu Agus , Sanubary Iklas , Mahmuda Diah 
Published: December 2022

Cocopeat machines that have been developed today, were carried out with variations in the speed of rotation, blade length, blade shape, and treatment of objects (coconut coir immersion). There has been no development of a cocopeat machine that focuses on variations of blade density. It is suspected that the blade density affects to the difference of cocopeat mass produced. This study was a true experiment. The dependent variable was cocopeat mass. The independent variables were blade density, consisting of σ1 (84/210π), σ2 (42/210π) and σ3 (21/210π). For each variation of the independent variable was conducted 10 experiments. The study sample was 30 pieces of coconut coir. The mass of each coconut coir was 50 grams. The engine's spin speed, length and blade shape, are the same for all samples. The data was analyzed using the t test at a significance level of 5%. The average mass values of cocopeat were σ1 ( = 16.5430; S1 = 1.9674), σ2 ( = 12.2650; S2 = 1.8341) and σ3 (μ3 = 10.0988; SD = 1.8943). The t test showed that the difference in the average value of cocopeat mass between groups were to12 = 5,030; to23 = 2,598; and to13 = 7,462. If t-table value for ν = 18 was 2,101, so . Ho was rejected and H1 accepted, so there was a difference of cocopeate mass that produced by poltesa cocopeat machine, which is effected by variations of blade density.
Wikipedia y la gobernanza de pares
Authors: Zanotti Agustín 
Published: December 2022

Wikipedia es una enciclopedia libre,​ políglota y colaborativa. En 2021 celebró su 20 aniversario, siendo destacada como un caso de éxito en la producción entre pares de bienes comunes. Se basa en una plataforma wiki en constante evolución, que permite a usuarios-editores coordinar el trabajo de creación y mejora de entradas. El proyecto es sostenido por una fundación junto a una red de organizaciones locales, siendo uno de los únicos mayores sitios de Internet gobernados por un modelo sin fines de lucro.
El artículo se basa en el concepto de gobernanza de pares. Concebido inicialmente para proyectos FLOSS, el término permite comprender procesos de participación y toma de decisión en la producción abierta de bienes informacionales. Se identifican tres niveles de gobernanza referidos a: 1. el proyecto (su evolución, organización e infraestructura); 2. la comunidad (su despliegue, institucionalidad y actividades); 3. el ecosistema (relaciones con actores externos e inserción).
Sobre la base de un abordaje documental, se propone un recorrido por momentos clave en el desarrollo de Wikipedia y sus iniciativas hermanas. Con ello se apunta a generar una comprensión panorámica del proyecto, al interior de un entramado dinámico y concentrado de medios conectivos.
Los resultados analizan el desarrollo de Wikimedia como una trayectoria sociotécnica. Sus primeros años marcan un despliegue exponencial, en los orígenes de la Web 2.0. El desarrollo comunitario fue una prioridad en la última década, con énfasis en la mayor equidad entre regiones, grupos y géneros, propiciando procesos de descentralización. Se consolidaron asimismo articulaciones con instituciones educativas, académicas y culturales, organismos internacionales y empresas de tecnología. Ello dio lugar a relaciones de cooperación y oposición, al tiempo que el proyecto sentó posicionamientos en la gobernanza global de Internet.
Philosophical Foundations of the Legal Language
Authors: DIDIKIN Anton , NOCHEVNAYA Viktoriya 
Published: December 2022

This paper analyzes the essence of the philosophical foundations of the legal language as it is used in certain theories in the legal philosophy. The purpose of the paper is to provide a full study of the legal language theory to determine its place in modern philosophical legal thought.
The paper used methods of the history of philosophy, especially the method of rational reconstruction, and is based on the interpretation of the classical philosophical and legal texts (W. Waismann, J. L. Austin, H. Kelsen, H. Hart).
The main result of the paper is the justification that the unity of logic and epistemology became the ground of application of the analytical method in the field of legal knowledge from the legal language point of view.
The main conclusion of this paper is that the linguistic analysis of legal concepts for the justification of the legal decisions and their consequences expands the horizons of analytical legal philosophy and allows us to reveal the essence of legal reality in a new way.
The paper was carried out within the framework of the Narikbayev KAZGUU University research project “Readability of Law”.
Pengaruh Iklan Pada Aplikasi Tik Tok Terhadap Minat Beli Mahasiswa Manajemen Bisnis Syariah IAIN Palopo
Authors: Murjiati Wahyu 
Published: December 2022

Paper ini tentang Pengaruh Iklan Dan Aplikasi Tik Tok Terhadap Minat Beli Mahasiswa IAIN Palopo. Penelitian ini bertujuan untuk mengetahui: (1) pengaruh iklan terhadap minat beli mahasiswa, (2) untuk mengetahui pengaruh aplikasi Tik Tok terhadap minat beli mahasiswa, (3) untuk mengetahui pengaruh iklan dan aplikasi Tik Tok terhadap minat beli mahasiswa. Jenis penelitian ini menggunakan penelitian kuantitatif. Sampel pada penelitian ini adalah program studi manajemen bisnis syariah IAIN Palopo sebanyak 63 orang responden ditentukan dengan teknik purposive sampling. Instrument penelitian ini menggunakan kuesioner dan teknik analisis data pada penelitian ini menggunakan uji instrument, uji persyaratan analisis, uji hipotesis, serta metode dari analisis yang digunakan adalah metode analisis linear berganda. Hasil penelitian ini menunjukkan bahwa: (1) Iklan berpengaruh positif dan signifikan terhadap minat beli mahasiswa, dengan nilai t tabel 1,295 dan tingkat signifikan 0,000 < 0,05. (2) Aplikasi Tik Tok berpengaruh terhadap minat beli beli mahasiswa, dengan nilai t tabel 1,295 dan tingkat signifikan 0,000 < 0,05. (3) Iklan dan aplikasi Tik Tok secara bersama-sama berpengaruh positif dan signifikan terhadap minat beli mahasiswa, dengan nilai F hitung 47,386 > F Tabel 2,39 dan tingkat signifikan 0,000 < 0,05. Besarnya pengaruh iklan dan aplikasi Tik Tok terhadap minat beli mahasiswa sebesar 61,2%.
Faktor-Faktor Determinasi Purchasing Decision Laptop Merek Apple (Studi Pada Pengunjung Paragon Mall Semarang)
Authors: Rohman Dwi Noor , Adinugraha Hendri Hermawan 
Published: December 2022

There are many brands of laptop, such as Acer, Toshiba, HP, Apple, Dell, Asus and Lenovo, etc which each has advantage and disadvantage also has its own enthusiasts. Based on market share in 2014-2016, all brands are fluctuating, but Apple, during the period 2014-2016 continues to decline from 7.4% in 2014 to 5.2% in 2015 even lower and lower it's 3.3% in 2016. That shows the consumers awarenes on Apple is also low. Many factors can influence on purchasing decisions of Apple Laptops, such as product quality, brand awareness, brand image and trust. The purpose of this study is to analyze the impact of product quality, brand awareness, brand image and trust toward purchasing decision of Apple Brand Laptops in Semarang. The population in this study were consumers who purchased Apple's brand laptop in Semarang city by 100 respondents as sample. The type of data used the primary data. Sampling techique used non-random type of purposive sampling. The data method collection using questionnaires and analysis techniques used multiple regression. The result shows that product quality, brand awareness, brand image, consumer trust has a positive and significant influence simultantly on purchasing decisions.
Qualitative and Quantitative Analysis of Nicotine, Nicotine Derivatives, and Nicotine-Related Alkaloid Optical Isomers: A Review
Authors: Perfetti Thomas A. , Dube Michael F. , Coleman William M. 
Published: December 2022

Summary
During the last 35 years technologies and hardware for the separation of enantiomers have advanced tremendously. Today, complete resolution of the enantiomers of nicotine and related compounds can effectively be attained within a few seconds and most often less than 10 minutes. In some unique cases, enantiomeric separation for nicotine-related compounds having a wide variety of functional groups has been demonstrated. Particularly, the successful wedding of short HPLC and SFC columns containing very small particle size materials bonded to chiral stationary phase materials coupled with information-rich detectors like electrospray ionization mass spectrometry/mass spectrometry has facilitated this remarkable transition. Taken collectively the HPLC and SFC technologies will allow for very rapid (seconds), reliable, and reproducible (% RSD routinely < 5%) for nicotine and related alkaloid enantiomers.
Design of Spaceflight Hardware for Plant Growth in a Sealed Habitat for Experiments on the Moon
Authors: Bowman Robert N. , McKay Christopher P. , Kiss John Z. 
Published: December 2022

Abstract
Plant growth experiments on near-term lunar landers need to be relatively small, lightweight, and self-contained. Here, we report on the design of a ~1 liter volume (1U Cubesat size) hermetically sealed habitat suitable for plant growth experiments during the first 10 days of seedling development of Arabidopsis thaliana and Brassica nigra. Images from a single interior camera show germination and provide quantitative data on seedling height, leaf area, and circumnutations. After 10 days with illumination from LEDs, the photosynthetic area of Arabidopsis cotyledons per seedling reached 300 mm2. Seedling height, inferred from the overhead camera using reference markers, reached was 15 ± 5 mm. Robust circumnutation in seedlings was observed. CO2 increased as expected due to respiration in the seeds during germination reaching levels of 5000 ppm after 3 days before declining to 3000 ppm on day 10 due to photosynthetic uptake. No CO2 was added to the sealed chamber during the experiments. These results show that fundamental studies of germination and initial growth can be conducted in a small volume (1 L) hermetically sealed unit with only an overhead camera and CO2 sensor. Hardware based on this approach would be suitable for lunar experiments on robotic landers.
PEDANG PENINGGALAN PRABU SILIWANGI DARI PANJALU, CIAMIS, JAWA BARAT
Authors: Tendi Tendi 
Published: December 2022

Pedang Sanghyang Borosngora adalah pedang yang diyakini oleh sebagian masyarakat Panjalu sebagai pemberian Sayyidina Ali kepada Prabu Borosngora. Pedang yang sekarang disimpan di Bumi Alit, Panjalu, dan merupakan artefak penting dalam sejarah masyarakat Ciamis dan Sunda, karena memuat nilai-nilai kultural masa lalu yang dapat diidentifikasi sebagai sumber penulisan sejarah. Informasi yang bias tentang Pedang Sanghyang Borosngora adalah masalah utama penelitian ini. Penelitian ini bertujuan untuk menarasikan sejarah Pedang Prabu Siliwangi dan bagian-bagiannya secara detail sesuai dengan pakem. Metode yang digunakan dalam penelitian ini adalah literatur review dengan menelaah sumber arsip, dan melakukan observasi langsung. Hasil penelitian menunjukkan bahwa sumber-sumber tradisional yang dianggap otoritatif oleh masyarakat terkait narasi sejarah Pedang Sanghyang Borosngora mengalami perubahan sejak awal abad ke-20 Masehi. Hal tersebut terjadi karena sejak masa itu Pedang Sanghyang Borosngora mulai dikenal sebagai Pedang Sayyidina Ali, padahal sebelumnya pedang itu diriwayatkan sebagai pedang pemberian Prabu Siliwangi kepada Raja Panjalu. Selain itu, ditemukan kesamaan yang spesifik dari pedang ini dengan pedang-pedang lain yang berasal dari Kerajaan Sunda. Dengan demikian, Pedang Sanghyang Borosngora lebih cocok untuk disebut sebagai Pedang Prabu Siliwangi.
The Sanghyang Borosngora sword is believed by some Panjalu people to have been given by Sayyidina Ali to King Borosngora. The sword is now stored in Bumi Alit, Panjalu, and is known as an important artifact in the history of the Ciamis and Sundanese people due to its old cultural values which can be identified as a source of historical writing. Biased information about the sword of Sanghyang Borosngora is the main issue of this research. This study aims to narrate the history of King Siliwangi's sword and its parts in detail according to its standard narration. The method used in this study was literature reviews by examining archival sources and making direct observations. The study suggests that traditional sources which are considered authoritative by the community regarding the historical narrative of the sword of Sanghyang Borosngora have changed since the early 20th century. Such a circumstance occurred because since the early 20th century the Sanghyang Borosngora Sword began to be known as the Sayyidina Ali Sword, even though previously the sword was narrated as a sword given by Prabu Siliwangi to King Panjalu. Additionally, specific similarities were found between this sword and other swords originating from the Kingdom of Sunda. Thus, the Sanghyang Borosngora Sword is more suitable to be called the Prabu Siliwangi Sword.
IDENTIFIKASI DAN PEMANFAATAN TANAMAN MASA JAWA KUNA: STUDI KASUS RELIEF RAMAYANA DAN KRESNAYANA CANDI PRAMBANAN
Authors: Setyawan Hari 
Published: December 2022

Kerajaan Mataram Kuno di Jawa Tengah merupakan kerajaan agraris yang berkembang pada masa Jawa Kuno abad ke-8-10 M. Salah satu data arkeologi yang monumental dari masa tersebut adalah Candi Prambanan yang memiliki pahatan relief naturalis dengan tema cerita Ramayana dan Kresnayana. Pada relief tersebut juga digambarkan tanaman yang dapat diidentifikasi jenisnya. Penggambaran tanaman pada relief Ramayana dan Kresnayana dapat digunakan sebagai petunjuk kondisi lingkungan Jawa Kuno di kawasan Prambanan pada masa lalu. Penelitian ini dilakukan dengan metode pengamatan langsung terhadap data yang dijaring secara purposive sampling. Sampel data yang diidentifikasi adalah tanaman-tanaman yang dipahatkan pada relief-relief Candi Prambanan. Hasil identifikasi data selanjutnya diinterpretasikan merujuk pada prasasti-prasasti dan naskah kesusastraan Jawa Kuno yang relevan. Sintesis penelitian ini menunjukkan bahwa pengelompokan dalam pengelolaan tanaman di kawasan Prambanan pada masa Jawa Kuno adalah tanaman pangan, tanaman komersial, tanaman keras, tanaman obat, dan tanaman hias. Lebih lanjut, dipahami pula bahwa pengelolaan tanaman pada masa Jawa Kuno sangat diperhatikan oleh penguasa. Aspek praktis penelitian ini memberikan peluang bagi tanaman-tanaman tersebut untuk dapat dibudidayakan kembali pada masa kini sebagai upaya konservasi lingkungan.
The Ancient Mataram Kingdom in Central Java was an agrarian state that developed during the ancient Javanese era of the 8th-10th century. One of the monumental archaeological data from that period is the Prambanan Temple which has naturalist relief sculptures with themes of the Ramayana and Kresnayana Epics. The reliefs also depict identifiable plants of that period. The depiction of plants in the reliefs of Ramayana and Kresnayana indicate the environmental conditions of Ancient Java in the Prambanan region in the past. This research was conducted by directly observing the data collected by purposive sampling. The data samples identified were plants carved on the reliefs of the Prambanan Temple. The results of data identification were then interpreted by referring to the relevant Old Javanese inscriptions and literary texts. The research synthesis shows that the grouping in the management of plants in the Prambanan area during the Old Javanese period were food plants, cash crops, perennials, medicinal plants, and ornamental plants. Furthermore, it is also understood that the management of plants during the Old Javanese period was highly considered by the authorities. The practical aspect of this research provides an opportunity for these plants to be cultivated again today as an environmental conservation effort.
ВПЛИВ Zn2+ ВОДНОГО СЕРЕДОВИЩА НА ДОБОВУ ЦИКЛІЧНІСТЬ ДИХАННЯ АЛОВИДІВ PLANORBARIUS CORNEUS S. L. (MOLLUSCA, GASTROPODA, PLANORBIDAE)
Authors: Babych Yu. V. 
Published: December 2022

We investigated the impact of the different concentrations of Zn2+ in the water (in the 0.5 MPL – 3 MPL range) on the chronological features of lung and direct diffusive respiration in representatives of superspecies complex of ramshorns Planorbarius corneus s. l. (“eastern” and “western” allospecies) from the Ukrainian river network. They have a bimodal respiration. Atmospheric oxygen goes into their true lungs through the breathing pore – pneumostome, – during the periodical rises up to the water surface tension film. And the oxygen soluble in the water is acquired by the osmosis through the epithelial body coverings and the surface of adaptive gill. Both ways are almost equally important for the oxygen supply of mollusks’ organisms.
Zn2+ ions are the powerful toxins of local effect for ramshorns. The excess of the MPL may lead to the impairment of stable homeostasis. Both P. corneus allospecies s. l. have clearly expressed diurnal cyclicality of their lung respiration (in the “day-night” rhythm). They perform 1.2–1.3 times more “inhales” during the day with the shorter (1.3–1.4 times) intervals. This apparently is the consequence of physiological activity increasing in the period of their most intensive life-giving metabolic processes occurring.
Under the 0.5 MPL of Zn2+ there were no statistically significant changes in lung and direct diffusive respirations indexes (comparing to the control) in both allospecies during the latent phase of their intoxication process. “Inhales” during the day were 1.1 time longer than during the night in experimental animals. This let mollusks replenish the amount of oxygen they underreceived due to the decreased number of night “inhales”.
Under MPL Zn2+ level the respirational indexes of ramshorns (number, length and volume of “inhales” and intervals between them) increased in average 1.1 times. Their feeding and moving behaviors visibly activated, which promoted the increasing of the daily frequency of their respiration rhythm. Under the 2 MPL concentration of Zn2+ there was further significant increasing (p