bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study on the Consumption Patterns of Processed Food Among Individuals With and Without Type 2 Diabetes
Authors: Mahajan Anu , Deshmane Aditi , Muley Arti 
Published: February 2025

ObjectiveThe study aims to analyse the eating patterns and consumption of ultra-processed food (UPFs) among individuals with and without diabetes.MethodsA comparative cross-sectional study was conducted across Pune, India, with 100 individuals with type 2 diabetes (T2D) and 208 without diabetes. A detailed FFQ (Food Frequency Questionnaire) developed by NOVA-UPF Screener with 33 ultra-processed food items was used to evaluate the consumption patterns of UPF.ResultsMost of the participants with diabetes have a habit of eating breakfast daily (68%), prefer lunch from home (72%), and about 20% avoid eating at a restaurant. While only 45.7% of the participants without diabetes have breakfast daily, and 88.4% prefer to eat lunch outside rather than homemade food. Comparative analysis shows that all 33 UPFs were consumed significantly less by individuals with diabetes than those without diabetes (p &lt; 0.001).ConclusionThe reduced intake of UPFs highlights greater dietary caution among individuals with T2D. Therefore, these findings emphasize the importance of promoting healthy eating habits and limiting UPF consumption among the general population to prevent the onset of metabolic conditions like diabetes.
Evaluating Bezlotoxumab-Fidaxomicin Combination Therapy in Clostridioides Infection: A Single-Center Retrospective Study from Aichi Prefecture, Japan
Authors: Hirai Jun , Mori Nobuaki , Hanai Yuki , Asai Nobuhiro , Hagihara Mao , Mikamo Hiroshige 
Published: February 2025

Background/Objectives: Clostridioides difficile infection (CDI) poses a significant healthcare challenge, with recurrence rates reaching 30%, leading to substantial morbidity and costs. Fidaxomicin (FDX) and bezlotoxumab (BEZ) have shown potential in reducing recurrence; however, real-world data on the efficacy of their combination in high-risk CDI patients remain limited. This study aimed to evaluate the efficacy and safety of FDX + BEZ compared with FDX alone in CDI patients with recurrence risk factors. Methods: CDI patients with ≥two recurrence risk factors treated with FDX alone or FDX + BEZ were analyzed. Sixteen factors were evaluated as risk factors for recurrent CDI based on findings from previous studies. Patients with FDX treatment duration <10 days or other CDI treatment prior to FDX were excluded. Outcomes included recurrence within 2 months, global and clinical cure rates, and adverse events. Univariate and multivariate analyses were performed to evaluate efficacy. Results: Among 82 patients, the FDX + BEZ group (n = 30) demonstrated significantly higher global (86.7% vs. 65.4%; p < 0.05) and clinical cure rates (90.0% vs. 69.2%; p < 0.05) compared with the FDX-alone group (n = 52), despite more severe cases in the combination group. Recurrence rates were non-significantly lower in the FDX + BEZ group (3.3% vs. 11.5%). Combination therapy also accelerated diarrhea resolution without additional adverse events. Multivariate analysis identified FDX + BEZ as significantly associated with improved clinical cure (adjusted odds ratio 4.167; 95% CI: 1.029–16.885). Conclusions: FDX + BEZ therapy offers superior efficacy and safety in CDI patients with recurrence risk factors, presenting a promising strategy for optimizing CDI management.
Determination of Heavy Metal Levels and Assessment of L. monocytogenes and Salmonella spp. Presence in Fishery Products and Mussels from the Marmara Region, Türkiye
Authors: Akkaya Esra , Muratoglu Karlo , Tarhan Duygu , Ozsobaci Nural Pastaci , Ercan Alev Meltem , Colak Hilal , Hampikyan Hamparsun , Bingol Enver Baris , Or Mehmet Erman , Andoni Egon , Ozuni Enkeleda , Gobbi Marco , Petrucci Linda , Di Cesare Federica , Cagnardi Petra , Curone Giulio , Balzaretti Claudia Maria , Giaccone Valerio , Castrica Marta 
Published: February 2025

This study evaluated heavy metal levels (Pb, Cd, Hg, As, Cu) and the presence of Salmonella spp. and Listeria monocytogenes in mussels and commonly consumed fishery products from the Marmara region of Türkiye. Health risks were evaluated using total hazard quotient (THQ) and hazard index (HI) values, while microbial risks in fresh and ready-to-eat (RTE) products were estimated via the Risk Ranger tool. Among 625 samples, Hg (36.96%; CI95 = 33.27–48.81), Pb (9.76%; CI95 = 7.67–12.34), and Cd (19.36%; CI95 = 16.45–22.64) exceeded permissible limits, except in crabs, which remained compliant. Anchovy, sardines, bluefish, shrimps, and octopus met EU Cd limits. Shrimps exhibited higher Asin levels than crabs (p < 0.05), while squids had significantly higher Asin than octopus but lower Pb (p < 0.05). Microbiological analysis detected Salmonella spp. in 4.00% of samples (CI95 = 2.50–6.30) and L. monocytogenes in 4.24% (CI95 = 2.70–6.59). Surmullet, bluefish, red mullet, crabs, mussels, and octopus tested negative for both, while anchovy was negative for Salmonella spp. only. THQ and HI assessments emphasized the need for environmental monitoring to mitigate heavy metal contamination. The detection of pathogens highlights the importance of stringent surveillance measures to ensure the safety of fishery products and bivalves.
Update on the Assessment of Glomerular Filtration Rate in Patients with Cancer
Authors: Costa e Silva Verônica T. , Xiong Fei , Mantz Lea , Sise Meghan E. , Herrmann Sandra M. , Kitchlu Abhijat 
Published: February 2025

Abstract
Accurate assessment of glomerular filtration rate (GFR) is key in patients with cancer, to guide drug eligibility, adjust dosing of systemic therapy, and minimize the risks of undertreatment and systemic toxicity. Several aspects of GFR evaluation in patients with cancer have been unclear, such as the choice of the GFR estimating equation and the overall lack of data on the reliability of new filtration markers, such as cystatin C. This uncertainty has led to concerns that inaccurate GFR estimation may have a large impact on clinical practice and research. Recent data have brought important developments to the field. The new and timely KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease raised important considerations and provided guidance on key aspects of GFR evaluation in patients with cancer. The guidelines cover valid estimating equations, incorporation of cystatin C in GFR estimation, drawbacks of using race, and acknowledge that non-GFR determinants of filtration markers may be prominent in certain patients, reducing the accuracy of GFR estimating equations, prompting greater utilization of GFR measurement. The aim of this review is to summarize advances in GFR evaluation in patients with cancer, considering the new KDIGO guidelines and other recent data.
CONSTRUÇÃO DE UMA TECNOLOGIA EDUCACIONAL SOBRE SEXUALIDADE DAS PESSOAS COM LESÃO MEDULAR
Authors: Hencklein Luana Cristina , Silva Ruana Luiz Ferreira da , Emidio Suellen Cristina Dias , Ferreira Adriana Gomes Nogueira , Oliveira-Kumakura Ana Railka de Souza 
Published: February 2025

Objetivo: construir uma tecnologia educacional, do tipo livro digital, para estudantes e profissionais da área da saúde sobre sexualidade das pessoas com lesão medular. Método: pesquisa metodológica baseada no Design Instrucional que seguiu as fases de Análise, Design e Desenvolvimento. Foi realizada análise contextual utilizando instrumentos validados que passaram por Análise de Bardin e categorização segundo os Descritores de Saúde. Posteriormente, foram identificadas as necessidades de aprendizagem e definidos os objetivos de aprendizagem segundo a Taxonomia de Bloom. Ao final, foi executada uma revisão integrativa para subsidiar o conteúdo. Na fase de Design, foi realizado planejamento inicial do livro digital e para fase de Desenvolvimento utilizou-se a ferramenta Canva e o Guidelines for Ebook Design para estruturação do material. Resultados: Para atender a competência de aquisição de conhecimento, foram selecionadas 23 temáticas e estabelecidos 17 objetivos educacionais no livro digital. Isso resultou num material com 66 páginas, distribuídas em 14 capítulos, abordando temáticas que afetam diretamente e indiretamente a sexualidade após a Lesão Medular. Conclusão: A tecnologia educacional construída, conforme o Design Instrucional, é pioneira e foi pautada na prática baseada em evidências. O livro digital aborda os cuidados e intervenções que podem ser utilizados por profissionais e estudantes para atender à sexualidade das pessoas com Lesão Medular.
Pelatihan Pembuatan Pakan Ternak Silase dan Pupuk Bokashi di Desa Jatimulyo Girimulyo Kulon Progo
Authors: Ngadat Ngadat , Mujiyanto Mujiyanto , Siswoyo Eko , Sudarto Sudarto , Setyoko Rahmad , Maryono Ari , Purnomo Danang Try , Sujiono Sujiono 
Published: February 2025

<p>Artikel ini membahasa tentang pelatihan pembuatan pakan ternak Silase dan pupuk Bokasih yang berbasis pada sistem fermentasi pada masyarakat Buddha di Desa Jatimulyo Kabupaten Kulonprogo. Metode yang digunakan dalam kegiatan pengabdian masyarakat ini adalah Asset Based Community Development (ABCD) yaitu model pemberdayaan masyarakat yang menekankan pada pemanfaatan aset dan potensi yang dimiliki oleh masyarakat untuk meningkatkan taraf hidup masyarakat. Memanfaatkan aset lokal secara optimal Bahan Baku Alami: Jerami, daun hijauan, dan kotoran ternak dimanfaatkan sebagai sumber utama, mengurangi ketergantungan pada bahan komersial. Pengetahuan Tradisional: Teknik pengolahan pakan dan pupuk berbasis fermentasi memanfaatkan kearifan lokal yang telah terbukti efektif. Penyuluhan tentang pakan ternak dan manfaat fermentasi dan bokasi, menyebarkan tentang pengetahuan pembuatan pakan ternak dan bokhasi Inovasi dalam formulasi pakan eksperimen dengan kombinasi bahan pakan yang berbeda untuk meningkatkan kandungan gizi atau menurunkan biaya. Meningkatkan produktivitas dan nilai tambah pakan fermentasi: Menambah kandungan nutrisi dan meningkatkan efisiensi pakan, mendukung pertumbuhan ternak yang lebih baik. Bokashi: Mengubah limbah menjadi pupuk organik berkualitas, meningkatkan kesuburan tanah untuk mendukung siklus pertanian. Kolaborasi dan Pemberdayaan komunitas melibatkan berbagai pihak (peternak, tokoh adat, pemuda) memperkuat solidaritas dan kerja sama. Sistem gotong royong dalam pengumpulan bahan baku, pengolahan, dan distribusi produk meningkatkan rasa kepemilikan masyarakat. Mendukung ekonomi berkelanjutan lingkungan: mengurangi limbah organik dengan mendaur ulang menjadi produk yang bermanfaat. Ekonomi: Hasil produksi pakan dan bokashi dapat digunakan sendiri atau dijual, meningkatkan pendapatan masyarakat.</p>
Edukasi Label Pangan Pilihan Lebih Sehat Untuk Mewujudkan Gizi Seimbang di MAN 2 Kota Bogor
Authors: Ramadhan Muhammad Fajar , Dianah Rosyda , Rahma Salma Faudziyah , Sari Astri Viidila , Nurrizqyah Alya , Salsabella Arsabella Alisa , Defina Nathasya Sarah , Andiani Cindy Oktavia 
Published: February 2025

<p>Indonesia saat ini mendapatkan tantangan bonus demografi yang ditandai dengan meningkatnya jumlah usia produktif. Permasalahan ini kerap dijumlah pada remaja terutama dalam kesehatan gizi. Dalam menghadapi permasalahan tersebut perlu adanya memaksimalkan kesehatan gizi pada remaja. Hal ini sejalan dengan tujuan pembangunan berkelanjutan untuk menciptakan sumber daya manusia yang cerdas, kuat, dan unggul. Maka dari itu, Nutrihealer hadir dalam rangka meningkatkan kesadaran dan pengetahuan remaja terhadap kesehatan gizi yang lebih optimal. Salah satu hal yang dapat dilakukan adalah melihat informasi gizi pada label kemasan. Tujuan dari penelitian ini adalah untuk mengukur efektivitas pemberian pendidikan gizi pada remaja MAN 2 Kota Bogor. Penelitian ini menggunakan metode penelitian kuantitatif. Populasi responden yang digunakan dalam penelitian ini sebanyak 30 siswa siswa berusia 16-18 tahun dari XII Fisika 2. Hasil penelitian menunjukkan bahwa p value &lt; 0,05 yang menunjukkan bahwa memberikan pendidikan gizi efektif dan dapat meningkatkan pengetahuan dan pemahaman siswa. Hal tersebut terbukti dari rata-rata pre-test 57,33 meningkatkan pada post-test menjadi 69,00. Disarankan ketika pemberian pendidikan gizi dilakukan secara berkelanjutan dengan melibatkan remaja perempuan dan remaja laki-laki berbasis kesetaraan gender agar memiliki hak yang sama dalam peningkatan kesehatan serta memaksimalkan penggunaan media maupun metode pemberian materi pendidikan gizi untuk menciptakan perilaku remaja yang positif dalam kesehatan.</p>
Assessing the impact of seasonal changes on advertising revenues in the age of digitalization and sustainability: A print-visual media business example
Authors: Camci Aykut , Aksoy Tamer 
Published: February 2025

This study mainly aimed to investigate the impact of seasonal changes on media advertising revenues (AR) in R environment through a visual-print media company example. So, the study primarily aimed to examine whether visual, print and internet ARs were affected by seasonal change. The study also aimed to indicate the trends of visual/ print/ and internet ARs over time in the light of seasonality. Furthermore, it was also aimed to make AR estimates for the next year with the best performing methods covering ARIMA and ETS. Methodologically, R programming language and its libraries were used together with ARIMA and ETS time series models. The data set consisted of a monthly ARs series consisting of 180 rows covering the period between January/2007-December/2021 and having a sufficient number of observations for the application of the models. Data were analyzed with R and next year’s forecasts were done with ARIMA and ETS. The study revealed that all AR types were affected by seasonal changes in the specified period and included seasonality, i.e. specially in the summer months. Additionally, it was observed that AR types have different trends despite containing seasonality. The study found that visual ARs denoted a slight downward trend including seasonality during the period. It was also indicated that print ARs reflected a very rapid and drastic downward trend covering seasonality. The study also revealed that internet ARs showed a very rapid and sharp upward trend compared to the other two AR types despite having seasonality. Furthermore, taking into account the calculated error metrics, it was found that the ARIMA model showed the best estimation performance in both i.e. visual and internet ARs. On the other hand, the ETS model indicated the best estimation performance in print ARs. Accordingly, estimations of the visual/print and internet ARs for the next year were made with the best performing methods. It was pointed out that estimated ARs included seasonality in the summer months and revealed similar results to the previous trends based on historical data.
UPAYA PENINGKATAN PENGETAHUAN DAN PEMERIKSAAN PADA LANSIA BINAAN DI RUMAH SAHABAT LANSIA DESA SIDANEGARA
Authors: Anita Ratna Faoziyah  , Titin Kartiyani  
Published: February 2025

Pada Lansia secara alamiah mengalami kemunduran baik secara fisik maupun psikis. Keluhan banyak bermunculan bersamaan dengan kemunduran tersebut seperti hipertensi,asam urat,diabetes melitu ataupun penyakit di persendian.komponen vital dalam kehidupan manusai salah satunya adalah Kesehatan,jika Kesehatan seseorang terganggu maka keberlangsungan hidup orang tersebut juga tidak akan berjalan baik (Apta,2011).Kegiatan pengabdian ini dilakukan sebagai upaya untuk memantau dan memberikan pendidikan Kesehatan kepada masyarakat umum melalui kegiatan penyuluhan dan pemeriksaan gratis yang ditujukan pada orang tua dan lansia yang berada di” Rumah Sahabat Lansia”, Kecamatan Cilacap Tengah, Kabupaten Cilacap. Kegiatan pengabdian masyarakat ini dilaksanakan setiap 1 bulan sekali pada tanggal 26 Juli 2024 diikuti oleh 78 peserta. Materi penyuluhan meliputi, materi tentang Hipertensi dan makanan sehat untuk menjaga Kesehatan lansia. Sebelum dilakukan kegiatan penyuluhan, terlebih dahulu peserta menjawab pertanyaan yang tedapat di kuesioner pre-test untuk mengetahui tingkat pengetahuan peserta terhadap materi yang akan disampaikan. Dan sebagai bahan evaluasi dilakukan pula penilaian terhadap pengetahuan peserta setelah penyuluhan dilakukan melalui kuesioner post-test. Berdasarkanhasil analisis tersebut diatas terdapat perbedaan yang signifikan antara kedua nilai pengetahuan masyarakat terkait fisioterapi dengan nilai signifikansi (2-tailed) p = 0.000 < 0.05. Kegiatan dilanjutkan dengan adanya pemeriksaan dan pengobatan gratis bagi semua peserta
Unraveling the Mediating Factors in Agricultural Training Transfer for Ugandan Extension Workers
Authors: Mukasa Pontious Mubiru , Miiro Richard , Obaa Bernard , Mutebi Henry , Kizza James , Kiwanuka Joseph 
Published: February 2025

Purpose: This paper investigated the mediation role of transfer work environment and training design on training transfer of agricultural management skills on the population of extension. Work environment and training design are expected to mediate the relationship between trainee characteristics (independent variables) and the transfer of training (dependent variable). Methodology: Data was collected from 281 agricultural extension workers who completed training on holistic agricultural management skills training programs at Makerere universities. This was achieved through a survey questionnaire anchored on a 5-point Likert scale and analyzed using Structural equation modelling using Analysis of Moment of Structures. Findings: Based on the results; we established a positive significant relationship between trainee characteristics, work environment, training design and perceived training transfer as insinuated by the Learning Transfer System Inventory. Additionally, the work environment and training design of extension workers partially mediate the relationship between trainee characteristics and perceived training transfer as well as training design between work environment and perceived training transfer. Implications: To optimize training outcomes, attention should not only be given to individual trainee characteristics but also to the conducive work environment and well-designed training programs. Fostering a supportive work context and tailoring training designs to align with organizational needs become crucial strategies.
Оценка влияния флейворов на анаэробный биоценоз
Authors: Карякин Михаил Александрович , Первова Инна Геннадьевна 
Published: February 2025

В данной статье детально рассмотрен вопрос влияния на анаэробный биоценоз меняющегося качественного режима поступления сточных вод пищевого предприятия. Выполнен эксперимент с использованием лабораторного метанреактора. Приведены сводные графические результаты эксперимента. Смоделирован процесс поступления сточных вод с содержанием основных антибактериальных компонентов (АБК) в сточной воде. Дана динамическая оценка влияния АБК на анаэробный биоценоз с достижением критических значений. Определены основные рекомендации использования анаэробной технологии с учётом поступления АБК.
A Sea of Black Holes: Characterizing the LISA Signature for Stellar-origin Black Hole Binaries
Authors: Ruiz-Rocha Krystal , Holley-Bockelmann Kelly , Jani Karan , Mapelli Michela , Dunham Samuel , Gabella William 
Published: February 2025

Abstract
Observations by the LIGO, Virgo, and KAGRA (LVK) detectors have provided new insights into the demographics of stellar-origin black hole binaries (sBHBs). A few years before gravitational-wave signals from sBHB mergers are recorded in the LVK detectors, their early coalescence will leave a unique signature in the ESA/NASA mission Laser Interferometer Space Antenna (LISA). Multiband observations of sBHB sources between the LISA and LVK detectors opens an unprecedented opportunity to investigate the astrophysical environment and multimessenger early alerts. In this study, we report the sBHB sources that are expected to be present in the LISA data derived directly from the hydrodynamic cosmological simulation Illustris. By surveying snapshots across cosmological volume, metallicity, and lookback time, we calculate the expected sBHBs present in the LISA data for various combinations of mission lifetimes and stellar population models. For stellar population estimates consistent with the LVK rates, we find that only 10 sBHBs across the Illustris snapshots would be detected with significant confidence for a 10 yr LISA mission, while a 4 yr LISA mission would detect only ∼1 sBHB. Our work paves the way for creating LISA mock data and benchmarking LISA detection pipelines directly using cosmological simulations.
Active Galactic Nucleus Feedback in Quiescent Galaxies at Cosmic Noon Traced by Ionized Gas Emission
Authors: Bugiani Letizia , Belli Sirio , Park Minjung , Davies Rebecca L. , Mendel J. Trevor , Johnson Benjamin D. , Khoram Amir H. , Benton Chloë , Cimatti Andrea , Conroy Charlie , Emami Razieh , Leja Joel , Li Yijia , Maheson Gabriel , Mathews Elijah P. , Naidu Rohan P. , Nelson Erica J. , Tacchella Sandro , Terrazas Bryan A. , Weinberger Rainer 
Published: February 2025

Abstract
We analyze ionized gas emission lines in deep rest-frame optical spectra of 14 massive (

log

M

*

>
10.2

M
⊙) quiescent galaxies at redshifts 1.7 < z < 3.5 observed with JWST/NIRSpec by the Blue Jay survey. Robust detection of emission lines in 71% of the sample indicates the presence of ongoing ionizing sources in this passive population. The Hα line luminosities confirm that the population is quiescent, with star formation rates that are at least 10 times lower than the main sequence of star formation at z ∼ 2. The quiescent sample is clearly separate from the star-forming population in line diagnostic diagrams, and occupies a region usually populated by active galactic nuclei (AGN). Analysis of the observed line ratios, equivalent widths, and velocity dispersions leads us to conclude that in most cases the gas is ionized by AGN activity, despite the lack of X-ray detections. We measure generally low values of the bolometric luminosity L
bol ∼ 1044 erg s−1 and Eddington ratio λ ∼ 10−2–10−3 for the central engines, typical of low-luminosity AGN. A subset of the sample also hosts ionized and neutral outflows, with ionized outflow velocities of the order of ∼1000 km s−1. Our results show, for the first time using a representative sample, that low-luminosity AGN are extremely common among quiescent galaxies at high redshift. These low-luminosity AGN may play a key role in quenching star formation and in maintaining massive galaxies quiescent from Cosmic Noon to z ∼ 0.
Tidal Disruptions of Stars by Supermassive and Intermediate-mass Black Hole Binaries: The Effects of the First-order Post-Newtonian Cross Terms
Authors: Wu Xiao-Jun , Luo Yan , Li Jie , Yuan Ye-Fei , Lin Wenbin 
Published: February 2025

Abstract
In the vicinity of galactic nuclei, stars orbiting supermassive black hole (SMBH) binaries can undergo tidal disruption events (TDEs) due to the Lidov–Kozai mechanism and three-body interactions. While numerical simulations have incorporated post-Newtonian (PN) corrections up to 2.5PN order, they have not accounted for the 1PN cross-term effects among the three bodies. In this study, we employ N-body simulations to investigate the impact of the 1PN cross terms on the orbits of stars around an intermediate-mass black hole (IMBH) perturbed by an outer SMBH. Our findings indicate that while the 1PN cross terms do not substantially affect the fractions of stellar outcomes, they can cause considerable variations in the orbits of stars around IMBH–SMBH binaries. Specifically, we find that the inclusion of the 1PN cross terms can lead to more concentrated distributions of semimajor axes. Furthermore, we observe heavy tails in the distributions of temporal shifts in TDEs when these cross terms are included, with the maximum change reaching about 106 yr, approaching the maximum integration time of this study. This investigation underscores the critical importance of incorporating the 1PN cross terms to ensure accuracy in comprehensive simulations of multibody systems in galactic nuclei. Notably, for stars partially disrupted by an SMBH binary, omitting these cross terms could result in erroneous predictions.