bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of induced stress on reactive and proactive control in depression
Authors: Masuyama Akihiro 
Published: January 2025

Background
Depression, a widespread mental health issue, is often marked by impaired cognitive control, particularly in managing proactive and reactive processes. The Dual Mechanisms of Control (DMC) framework differentiates between these two modes of cognitive control: proactive control involves sustained goal maintenance, while reactive control is more stimulus-driven and transient. Stress, known to exacerbate cognitive dysfunction in depression, may influence the balance between these control processes, though the specific effects remain poorly understood. This study aimed to investigate how acute stress influences proactive and reactive control in individuals with depressive symptoms.

Methods
A total of 142 participants were divided into high-stress and control conditions and further categorized based on their depression levels, measured using the Beck Depression Inventory-II (BDI-II). Cognitive control was assessed using the AX-Continuous Performance Task (AX-CPT), both before and after exposure to a stress-inducing anagram task, which was designed to differentiate between high-stress and low-stress conditions.

Results
Participants exposed to the high-stress condition reported significantly greater stress and fatigue levels compared to the control group, validating the stress manipulation. Although the balance between reactive and proactive control, as measured by the Proactive Behavioral Index (PBI), did not show significant changes, depressive individuals in the high-stress condition exhibited a significant decline in their ability to retain contextual information, as indicated by a reduction in the d’-context index. This suggests that depressive individuals may be more prone to stress-induced difficulties in proactive control.

Discussion
These findings highlight the selective impact of stress on proactive cognitive control in individuals with depressive symptoms, shedding light on a potential cognitive vulnerability in depression. While the balance between reactive and proactive control remained stable, the impaired retention of contextual information post-stress points to a specific deficit in proactive control. This could have implications for targeted cognitive interventions, such as cognitive control training, aimed at enhancing resilience against stress in depressive populations. Future research should explore the long-term effects of stress on cognitive control, particularly in clinically diagnosed individuals.
Management of Leaf Blight and Node Blight Diseases Indian Barnyard Millet (Echinochloa frumentacea (Roxb)
Authors: Paramasivan M. , Deivamani M. , Thangeswari S. , Ramjegathesh R. , Thangam A. , Senthilkumar M. , Malathi S. , Satya V.K. 
Published: January 2025

A study on the management of important diseases of rainfed kuthiraivali was carried out through biological control and fungicides in combination with seed treatment and foliar application methods and different intervals of diseases incidence. The leaf blight pathogen was isolated from the affected leaf; the isolated fungus's dark grayish-colored, fluffy mycelia were observed on the PDA medium. The mycelium was grey to olivaceous green, profusely branched, and septate. Conidiophores were single or in small groups, straight to flexuous, septate, smooth, and dark brown. Measuring 3.5 µm x 0.865 µm (1 µm), The disease incidence was observed at 15-day intervals using the percent disease index. Among three years, the seed treatment (10gm/kg) of Pseudomonas fluorescens (TNAU Pf1) followed by foliar application of Carbendazim + Mancozeb 2 gm/lit decreases the leaf blight diseases (63.63% reduction over control) and also recorded an increased yield of 1075 kg/ha of kuthiraivali. Seed treatment with Pseudomonas fluorescens Pf1 combined with foliar fungicide sprays significantly enhances yield and cost-benefit ratio under rainfed conditions while effectively managing seed-borne and foliar diseases.
Impact of Heterotic Potential in Rice (Oryza sativa L.) for Certain Yield and its Contributing Traits in Salt-Affected Soil
Authors: Yadav P. K. , Singh P. K. , Verma O. P. , Kumar Ashwani 
Published: January 2025

The present investigation was undertaken with the objectives to estimate genetic variability for yield and yield contributing components. The experimental materials of rice for this investigation comprised of 22 genotypes as lines (female) and three testers (male) viz., Narendra Usar 3, NDR 359 and CSR 36. Each of the three testers was crossed with 22 lines during Kharif, 2013. The experiment was based on the evaluation of a line × tester set of 66 hybrids (F1s) along with their 22 parents and check varieties viz., Narendra Usar 3 and Arize 6444, for twelve quantitative trait in salt affected soil in randomized block design with three replications. The analysis of variance revealed that all the treatments, parents, parent vs crosses, crosses, lines and lines x testers were highly significant for majority of the yield and its contributing traits indicated sufficient variation among the treatment/materials under study.In the present investigation, a wide range of variation in estimates of heterobeltiosis and standard heterosis in positive and negative directions was observed for grain yield per plant and its contributing components. In case of grain yield per plant heterobeltiosis ranged from -1.76 per cent (IR 47427-2B-2-2B-1-1× Narendra Usar 3)to 100.14 per cent (Kashturi Chandauli× NDR 359), standard heterosis over SV1varied from -30.85 per cent (AGAMI MI× CSR 36) to 50.84 per cent (Kashturi Chandauli× NDR 359) while over it ranged from -3677 per cent (AGAMI MI× CSR 36) to 37.92 per cent (Kashturi Chandauli× NDR 359). Kashturi Chandauli× NDR 359, IR 74095 AC 5 × NDR 359, Narendra 6096 × NDR 359, Sarjoo 52 × Narendra Usar 3 and Kashturi Chandauli× Narendra Usar 3 were found highly significant over BP, while Kashturi Chandauli× NDR 359, IR 74095 AC 5 × NDR 359, Narendra 6096 × NDR 359, Sarjoo 52 × Narendra Usar 3 and Jaya × Narendra Usar 3 had highly significant over standard variety SV1. Further Kashturi Chandauli × NDR 359, IR 74095 AC 5 × NDR 359, Narendra 6096 × NDR 359, Sarjoo 52 × Narendra Usar 3 and Jaya × Narendra Usar 3 were found to be highly significant over SV2 for grain yield per plant. The estimates of heterosis were attributed to genetic interaction arising from both additive as well as high degree of non additive gene action for major physiological traits. Two physiological traits viz., biological yield per plant and harvest index followed by spikelets per panicle, 1000- grain weight, L: B ratio and flag leaf area remained as major contributors to heterobiltiosis and standard heterosis. It reflects that emphasis should be given to select these traits to enhance the production and productivity in salt affected soil.
Evaluation of the In vitro Anthelmintic Activity of Melia azedarach and Swertia chirata Aqueous Extracts Against Haemonchus contortus
Authors: Das Supradip , Hembram Ananta , Jas Ruma , Ganganapalli Mary Sunanda , Haque Rakibul , Pandit Soumitra 
Published: January 2025

Aim: This research intended to assess the in vitro anthelmintic properties of Mahaneem leaves (Melia azedarach) and whole plant of Chirata (Swertia chirata).
Study Design: In vitro study was conducted aganist Haemonchus contortus eggs and adult stage by egg hatch assay (EHA) and adult motility inhibition test (AMIT).
Place and Duration of Study: This study was conducted in the departement of Veterinary Parasitology, WBUAFS, Kolkata-37 between November,2023 to August, 2024
Methodology: The aqeous extract of Mahaneem and Chirata whole plants were prepared by decoction method, dried and desolved in 2% Dimethyl Sulfoxide to make desirable concentration of extract solutions. Adult Haemonchus contortus was collected from freshly slaughter abomasum of sheep for separation of eggs and active motile adult was used for AMIT. Each EHA and AMIT was performed in triplicate.
Results: The results revealed that both Chirata and Mahaneem extracts shows anthelmintic activity against Haemonchus contortus. Chirata extract had better efficacy against both eggs and adult stage of Haemonchus contortus compare to Mahaneem leave extract. In EHA, Chirata extract efficacy at the dose of 50 mg/ml and 25 mg/ml was more statistically significant (p<0.05) than Mahaneem extract. In AMIT, also Chirata shows significantly more efficacy at 50mg/ml and 25 mg/ml than Mahaneem,but at the dose rate of 10 mg Mahaneem shows better efficacy (38.88 2.22) than Chirata (31.11 2.22) extract. At 50 mg/ml concentration after 10 hours of experiment Chirata shows higest efficacy (82.22 2.22) compare to Mahaneem (57.77 2.22).
Conclusion: Both Chirata and Mahaneem aqueous extract can potentially be effective against Haemonchus contortus and other GINs in small rumunats when administer properly with selected doses.
Effect of Ninety-day Repeated Adiministration of Leaf Extract of Solanum anomalum on Rats
Authors: Okokon Jude E. , Etuk Idongesit C. , Udobang John A , Osigwe Chinyelu C. , Florence Uwaeme Ugonma , ISE Uduak P. 
Published: January 2025

The leaves and fruits of Solanum anomalum Thonn. ex Schumach are used locally for the treatment of pains, fever and malaria among others. Effect of 90-day repeated administration of S. anomalum leaf extract on rats was investigated. Oral administration of the leaf extract (70, 140 and 210 mg/kg) to rats (male and female) was carried out daily for 90 days and the rats were sacrificed after being anaesthesized with light diethyl ether at the completion of the administration. Oral treatment of rats subchronically with S. anomalum leaf extract had no significant (p>0.05) effect on rats’ body weights, hemoglobin concentration, WBC, RBC, platelets counts, percentages of PCV and eosinophils relative to control. However, percentages of neutrophils, monocytes and basophils were elevated significantly (p <0.05-0.01) at the highest dose (210 mg/kg), while lymphocytes percentage was reduced. The leaf extract had no significant (p>0.05) effect on bleeding and clotting times relative to control. The leaf extract non dose-dependently caused significant (p<0.05) lowering of ALT, AST and ALP levels. However, total and direct bilirubin levels were elevated significantly (p<0.01-0.001) only at raised leaf extract’ doses (140 and 210 mg/kg). The leaf extract exerted no significant (p>0.05) changes on uric acid, bicarbonate, chloride, potassium and sodium levels, but lowered urea, creatinine, total cholesterol, triglyceride, HDL, VLDL and LDL levels of rats significantly (p<0.05) relative to control. There was no observable distortion of heart, testis and spleen histologies. Distortion in the histology of livers, kidneys, ovaries and brains of rats were observed at raised extract doses (140 and 210 mg/kg). High doses of the leaf extract should be avoided to prevent serious toxic effects.
Evaluation of the Microbiological Quality of Bathing Waters in the Mamou Region, Republic of Guinea
Authors: DIALLO Souleymane , BAH Boubacar Sidy Sily , DIALLO Mohamed , BALAMOU Ouo-Ouo 
Published: January 2025

The bacteriological quality of bathing water is a major public health issue. The aim of this study is to assess the correlation between the bacteriological quality of bathing water and the risk of disease outbreaks. The study was prospective in nature, and ran from June to December 2022. Fifty-nine (59) samples were taken from water sources used for bathing. The membrane filtration method and the direct inoculation method were used. In Mamou, the results showed that EI and E. coli exceeded WHO threshold values in rivers and streams, with 2/4 (20%) and 8/11 (80%) respectively. Whereas in Pita, Enterococci had exceeded these standards in 25% of backwater and 75% of streams, and E. coli in 14.28 and 85.71% of rivers and streams respectively. E. coli (streams: 66.66% and backwater: 33.33%) and E. coli (streams: 83.33% and backwater: 16.66%) values exceeded WHO thresholds in Dalaba. Many sites had bacterial loads above WHO thresholds. This would be an important element to say that these water sources constitute a real public health issue.
Exposure to Arsenic and Subclinical Cardiovascular Disease in 9- to 11-Year-Old Children, Syracuse, New York
Authors: Gump Brooks B. , Heffernan Kevin , Brann Lynn S. , Hill Dustin T. , Labrie-Cleary Charlotte , Jandev Vikrant , MacKenzie James A. , Atallah-Yunes Nader H. , Parsons Patrick J. , Palmer Christopher D. , Roberts Austin A. , Bendinskas Kestutis 
Published: June 2023

ImportanceStudies in adults have demonstrated associations between arsenic exposure and clinical and subclinical cardiovascular disease (CVD). No studies to date have considered potential associations in children.ObjectiveTo examine the association between total urinary arsenic levels in children and subclinical indicators of CVD.Design, Setting, and ParticipantsThis cross-sectional study considered 245 children, a subset from the Environmental Exposures and Child Health Outcomes (EECHO) cohort. Children from the Syracuse, New York, metropolitan area were recruited from August 1, 2013, until November 30, 2017, with enrollment throughout the year. Statistical analysis was performed from January 1, 2022, to February 28, 2023.ExposuresTotal urinary arsenic was measured using inductively coupled plasma mass spectrometry. Creatinine concentration was used to adjust for urinary dilution. In addition, potential exposure routes (eg, diet) were measured.Main Outcomes and MeasuresThree indicators of subclinical CVD were assessed: carotid-femoral pulse wave velocity, carotid intima media thickness, and echocardiographic measures of cardiac remodeling.ResultsThe study sample included 245 children aged 9 to 11 years (mean [SD] age, 10.52 [0.93] years; 133 [54.3%] female). The geometric mean of the creatinine-adjusted total arsenic level in the population was 7.76 μg/g creatinine. After adjustment for covariates, elevated total arsenic levels were associated with significantly greater carotid intima media thickness (β = 0.21; 95% CI, 0.08-0.33; P = .001). In addition, echocardiography revealed that elevated total arsenic was significantly higher for children with concentric hypertrophy (indicated by greater left ventricular mass and greater relative wall thickness; geometric mean, 16.77 μg/g creatinine; 95% CI, 9.87-28.79 μg/g) relative to the reference group (geometric mean, 7.39 μg/g creatinine; 95% CI, 6.36-8.58 μg/g). With respect to exposure source, significant geographic clustering of total arsenic was found in 1 urban area of Syracuse, New York.Conclusions and RelevanceThese findings suggest a significant association between arsenic exposure and subclinical CVD in children. Elevated total arsenic levels were found in an area of Syracuse with known elevations of toxic metals from industrial waste, suggesting historical pollution as a possible source. Given the novelty and potential importance of this association, further research is needed to confirm our findings. Any potential effect of urinary arsenic exposure in childhood on actual clinical CVD outcomes in adulthood remains to be determined.
Peptide‐Enabled Thrombus‐Targeting Nanoparticles for Highly Effective Targeted CT Imaging and Eradication of Thrombi
Authors: Lu Leihao , Bao Qing , Miao Yao , Cheng Qichao , Chen Yuyin , Yang Shuxu , Mao Chuanbin , Yang Mingying 
Published: June 2023

AbstractThrombotic disease poses a significant threat to human health as it blocks blood vessels and leads to severe symptoms. Effective treatment requires targeted therapy and precise localization of the thrombus, but traditional drugs are limited in their targeting ability and ability to locate the thrombus. To overcome these issues, a nanoparticle capable of both thrombus targeting and computed tomography (CT) imaging is developed. Phage display technology is used to screen for the thrombus‐targeting peptide termed GK, which is then linked to the surface of macroporous silica (Mp‐SiO2) with a Bi core to create Mp‐Bi@SiO2‐GK. The large pores of Mp‐Bi@SiO2‐GK enable the transport of the drug Urokinase (UK), while the Bi core provides the capabilities of CT imaging and photothermal therapy. The Mp‐Bi@SiO2‐GK nanoparticles precisely target thrombi in mouse carotid arteries and locate them via CT imaging. Furthermore, the combination of Bi‐enabled photothermal therapy and UK‐induced chemotherapy enhance the thrombolysis efficiency. Treatment with Mp‐Bi@SiO2‐GK nanoparticles do not harm tissues/organs or affect liver/kidney metabolism. These results show that Mp‐Bi@SiO2‐GK exhibits precise thrombus targeting and efficient imaging/treatment capability, making it a promising tool for the diagnosis and treatment of thrombosis.
Overcoming Charge Confinement in Perovskite Nanocrystal Solar Cells
Authors: Yang Wenqiang , Jo Seung‐Hyeon , Tang Yipeng , Park Jumi , Ji Su Geun , Cho Seong Ho , Hong Yongseok , Kim Dong‐Hyeok , Park Jinwoo , Yoon Eojin , Zhou Huanyu , Woo Seung‐Je , Kim Hyeran , Yun Hyung Joong , Lee Yun Seog , Kim Jin Young , Hu Bin , Lee Tae‐Woo 
Published: June 2023

AbstractThe small nanoparticle size and long‐chain ligands in colloidal metal halide perovskite quantum dots (PeQDs) cause charge confinement, which impedes exciton dissociation and carrier extraction in PeQD solar cells, so they have low short‐circuit current density Jsc, which impedes further increases in their power conversion efficiency (PCE). Here, a re‐assembling process (RP) is developed for perovskite nanocrystalline (PeNC) films made of colloidal perovskite nanocrystals to increase Jsc in PeNC solar cells. The RP of PeNC films increases their crystallite size and eliminates long‐chain ligands, and thereby overcomes the charge confinement in PeNC films. These changes facilitate exciton dissociation and increase carrier extraction in PeNC solar cells. By use of this method, the gradient‐bandgap PeNC solar cells achieve a Jsc = 19.30 mA cm−2 without compromising the photovoltage, and yield a high PCE of 16.46% with negligible hysteresis and good stability. This work provides a new strategy to process PeNC films and pave the way for high performance PeNC optoelectronic devices.
Lactate Efflux Inhibition by Syrosingopine/LOD Co‐Loaded Nanozyme for Synergetic Self‐Replenishing Catalytic Cancer Therapy and Immune Microenvironment Remodeling
Authors: Wu Shengming , Xu Lehua , He Chenlong , Wang Peng , Qin Jingwen , Guo Fangfang , Wang Yilong 
Published: June 2023

AbstractAn effective systemic mechanism regulates tumor development and progression; thus, a rational design in a one‐stone‐two‐birds strategy is meant for cancer treatment. Herein, a hollow Fe3O4 catalytic nanozyme carrier co‐loading lactate oxidase (LOD) and a clinically‐used hypotensor syrosingopine (Syr) are developed and delivered for synergetic cancer treatment by augmented self‐replenishing nanocatalytic reaction, integrated starvation therapy, and reactivating anti‐tumor immune microenvironment. The synergetic bio‐effects of this nanoplatform stemmed from the effective inhibition of lactate efflux through blocking the monocarboxylate transporters MCT1/MCT4 functions by the loaded Syr as a trigger. Sustainable production of hydrogen peroxide by catalyzation of the increasingly residual intracellular lactic acid by the co‐delivered LOD and intracellular acidification enabled the augmented self‐replenishing nanocatalytic reaction. Large amounts of produced reactive oxygen species (ROS) damaged mitochondria to inhibit oxidative phosphorylation as the substituted energy supply upon the hampered glycolysis pathway of tumor cells. Meanwhile, remodeling anti‐tumor immune microenvironment is implemented by pH gradient reversal, promoting the release of proinflammatory cytokines, restored effector T and NK cells, increased M1‐polarize tumor‐associated macrophages, and restriction of regulatory T cells. Thus, the biocompatible nanozyme platform achieved the synergy of chemodynamic/immuno/starvation therapies. This proof‐of‐concept study represents a promising candidate nanoplatform for synergetic cancer treatment.
Thermal behaviors of ethylene vinyl acetate encapsulants in fielded silicon photovoltaic modules
Authors: Palmiotti Elizabeth C. , Roberts Christine C. , King Bruce H. 
Published: June 2023

AbstractAging of silicon photovoltaic (PV) module packaging is one of the greatest limiters of PV module service lifetimes. Module characterization typically focuses on power degradation metrics, which do not convey the complexities of often simultaneous degradation mechanisms. In this work, PV modules with pristine references and known fielding histories were investigated by non‐destructive and destructive methods. Modules from Canadian Solar, Mission Solar, and Hanwha Q‐Cells were fielded for up to three years; select modules were removed from fielding each year for coring to allow for characterization of the encapsulant. Modules are commonly encapsulated with two protective layers of partially‐crystalline ethylene vinyl acetate (EVA) polymer that must undergo a crosslinking reaction to achieve desired properties. The extent of crystallinity of the encapsulants as studied by differential scanning calorimetry showed differences between manufacturers and over time. Some encapsulants showed different magnitudes of crystal sizes which changed after fielding; encapsulants with the monodisperse crystal sizes did not change with fielding. This is due to differences in thermal history. These results have implications for stress development during module aging, since EVA crystal melting and crosslinking reactions can result in encapsulant density changes.
3D printed heterogeneous cation exchange membrane processed using stereolithography
Authors: Zárybnická Lucie , Meloun Zbyšek , Šafka Jiří , Truxová Veronika , Dvořák Karel , Machotová Jana 
Published: June 2023

AbstractMembrane chemistry belongs to the field in which 3D printing can advantageously also be used because of enabling the production of prototypes with precisely defined dimensions. The presented work aimed to develop new polymeric compositions for heterogeneous cation exchange membranes manufactured using stereolithography (SLA) from commercially available materials. Three types of photo‐curable thermoset resins (acrylic resin and two types of epoxy resins) were used as polymer matrixes in combination with strong acid cation exchange resin (CER) powder. The membrane production consisted of several stages, namely mixing the photo‐curable resin with finely ground CER powder, processing using SLA, and appropriate post‐curing using UV light and elevated temperature. The work aimed to monitor the influence of the photo‐curable resin type and post‐curing on the microstructural, electrochemical, and mechanical properties of resulting membrane objects. The results revealed that heterogeneous cation exchange membranes could be processed using SLA from the mixture of the acrylic photo‐curable resin and CER powder (weight ratio of 60/40) without the need for post‐curing. These products exhibited high permselectivity (93%), high ion exchange capacity (2.23 meq⋅g−1), and sufficiently low electrical resistance (2200 Ω⋅cm), which predetermines them for efficient electrophoretic separation.