bluuebunny/crossref_metadata_2025_split huggingface dataset:
INVESTIGATION OF THE LOADING AT THE KNEE JOINT COMPLEX USING AN EMG-BASED CONSTITUTIVE LAW FOR SKELETAL MUSCLE FORCE
Authors: KNODEL NATHAN B. , CALVERT L. BRIE , BYWATER EMILY A. , LAMIA JOSEPH P. , PATEL SHIV N. , NAUMAN ERIC A. 
Published: July 2023

This study investigated the predictive ability of the skeletal muscle force model presented by Knodel et al. [Knodel NB, Lawson LB, Nauman EA, “An emg-based constitutive law for force generation in skeletal muscle-part i: Model development,” J Biomech Eng (in press), doi: 10.1115/1.4053568] on the knee joint. It has previously been validated on the ankle joint [Knodel NB, Calvert LB, Bywater EA, Lamia JP, Patel SN, Nauman EA, “An emg-based constitutive law for force generation in skeletal muscle-part ii: Model validation on the ankle joint complex,” Submitted for Publication] and this paper aimed to identify how well it, and the solution process, performed on a more complex articulation. The knee joint’s surrounding musculoskeletal tissue loading was also identified. Ten subjects (five male and five female) performed six exercises targeting the muscles that cross the knee joint. Motion capture, electromyography, and force plate data was collected during the exercises for use in the analysis program written in MATLAB and magnetic resonance images were used to observe subject-specific ligament and tendon data at the knee articulation. OpenSim [Delp, SL, Anderson FC, Arnold AS, Loan P, Habib A, John CT, Guendelman E, Thelen DG, “Opensim: Open-source software to create and analyze dynamic simulations of movement,” IEEE Trans Biomed Eng 54(11):1940–1950, 2007, doi: 10.1109/TBME.2007.901024] was used for scaling a generic lower extremity anatomical model of each subject. Five of the six exercises were used to calculate each muscle’s constant, [Formula: see text] [Knodel NB, Lawson LB, Nauman EA, “An emg-based constitutive law for force generation in skeletal muscle-part i: Model development,” J Biomech Eng (in press), doi: 10.1115/1.4053568; Knodel NB, Calvert LB, Bywater EA, Lamia JP, Patel SN, Nauman EA, “An emg-based constitutive law for force generation in skeletal muscle-part ii: Model validation on the ankle joint complex,” Submitted for Publication], and the sixth was used as a testing set to identify the model’s predictive ability. Average percent errors ranged from 9.4% to 26.5% and the average across all subjects was 20.6%. The solution process produced physiologically relevant muscle forces and the surrounding tissue loading behaved as expected between the various exercises without approaching respective tensile strength values.
Optimization of Multi-Component Topology and Material Orientation Design of Composite Structures Using AI
Authors: Srivastava Neeraj 
Published: July 2023

Composite materials offer a wide range of advantages in terms of strength, weight, and versatility, making them a popular choice for structural applications. The performance of composite structures depends not only on the material constituents but also on the topology and arrangement of these components. However, designing an optimal configuration that maximizes the desired performance metrics can be a challenging task due to the large design space and complex interactions between the components. It presents a novel approach for optimizing the multi-component topology and material orientation design of composite structures using artificial intelligence (AI) techniques. The objective is to develop an automated and efficient methodology that can identify the most optimal configuration for a given set of performance requirements. The proposed methodology combines AI algorithms, such as genetic algorithms and machine learning, with advanced computational modeling techniques. The genetic algorithms are employed to explore the design space and search for the best combination of topology and material orientations. Concurrently, machine learning techniques are utilized to model the complex relationships between the design variables and performance metrics, enabling the identification of design patterns and accelerating the optimization process.
To achieve this, a comprehensive framework is established, encompassing the generation of an initial population of candidate designs, evaluation of their performance using numerical simulations or experimental testing, application of genetic algorithms to iteratively evolve the population by selecting the fittest designs and introducing variations, and utilization of machine learning models to predict the performance of new designs and guide the optimization process. The effectiveness of the proposed methodology is demonstrated through a case study involving the design of a composite aerospace structure. The results reveal that the AI-based optimization approach significantly outperforms traditional trial-and-error methods, leading to improved performance metrics such as strength, stiffness, and weight.
The findings have significant implications for the design and manufacturing of composite structures in various industries, including aerospace, automotive, and civil engineering. The automated optimization process enabled by AI techniques can efficiently explore the design space, identify innovative solutions, and ultimately enhance the overall performance of composite structures.
User identification system based on 2D CQT spectrogram of EMG with adaptive frequency resolution adjustment
Authors: Kim Jae Myung , Choi Gyu Ho , Pan Sungbum 
Published: July 2023

Abstract
User identification systems based on electromyogram (EMG) signals, generated inside the body in different signal patterns and exhibiting individual characteristics based on muscle development and activity, are being actively researched. However, nonlinear and abnormal signals constrain conventional user identification using EMG signals in improving accuracy by using the 1-D feature from each time and frequency domain. Therefore, multidimensional features containing time-frequency information extracted from EMG signals have attracted much attention to improving identification accuracy. We propose a user identification system using constant Q transform (CQT) based 2D features whose time-frequency resolution is customized according to EMG signals. The proposed user identification system comprises data preprocessing and normalization, CQT-based 2D image conversion, convolutional feature extraction, and classification by convolutional neural network. The experimental results showed that the accuracy of the proposed user identification system using CQT-based 2D spectrograms was 97.5%, an improvement of 15.4% and 2.1% compared to the accuracy of 1D features and short- time Fourier transform-based user identification, respectively.
Health Outcomes in Postmenopausal Women with Polycystic Ovary Syndrome History: Systematic review and meta-analysis
Authors: Wu han , Fan Lina , Sun Lixia , Wang Haoran , Liu Mengchen , Sun Xianchang , Zhang Wenjuan 
Published: July 2023

Abstract
Backgrounds
Polycystic ovary syndrome (PCOS) is one of the most common reproductive and endocrine diseases that can impact a woman's health status throughout her life. Concerns have always been focused on women at adolescent or reproductive age, however the outcomes of PCOS occurring at their postmenopausal age have not been clarified.
Methods
We conducted this systematic review and meta-analysis to identify the association between health outcomes of postmenopausal women and their experiences of PCOS. The relevant literature was searched from Embase databases, Cochrane Library and PubMed. The quality of included studies was assessed using the Newcastle-Ottawa Scale (NOS). The weighted mean differences (WMDs) and their 95% confidence intervals (CIs) of relevant health parameters were calculated between postmenopausal women with PCOS history and the healthy controls. Pooled odds ratio (OR) was used to evaluate the association between PCOS and specific health outcome.
Results
Our study included 15 studies with 757 postmenopausal women with history of PCOS and 4211 controls. Compared to the controls, the following parameters were significantly higher among postmenopausal women with PCOS history: body mass index (BMI) (WMD = 3.28, 95%CI: 1.24 to 5.31, I2 = 96%, P = 0.002), waist circumference (WMD = 7.01, 95%CI: 3.24 to 10.78, I2 = 76%, P < 0.001), waist/hip ratio (WHR) (WMD = 0.03, 95%CI: 0.00 to 0.06, I2 = 93%, P = 0.030), triglycerides (WMD = 0.40, 95%CI: 0.04 to 0.77, I2 = 75%, P = 0.030), total testosterone (WMD = 0.16, 95%CI: 0.09 to 0.22, I2 = 51%, P < 0.001) and free androgen index (FAI) (WMD = 1.82, 95%CI: 1.05 to 2.59, I2 = 91%, P < 0.001). In addition, PCOS history was significantly associated with the outcomes of type 2 diabetes (OR = 4.09, 95%CI: 1.62 to 10.33, I2 = 72%, P = 0.003) and metabolic syndrome (OR = 3.93, 95%CI: 1.17 to 13.22, I2 = 67%, P = 0.030).
Conclusions
This study illustrated that women exposed to PCOS might have higher risk of health problems at their postmenopausal age. Our findings shed light on requirement of early intervention among women with PCOS, as well as targeted health supports to postmenopausal women who have a history of PCOS.
Experience of Mass Switching to Biosimilar Drugs in Patients with Immune-Mediated Inflammatory Rheumatic Diseases. Effectiveness and Safety. Intercambiosim Project
Authors: Corredor David Castro , Pascual Luis Ángel Calvo , Águila Vera Lucía Áreas del , Manzanedo Verónica Salas , Huaranga Marco Aurelio Ramírez , Peñas Marina González , Romero Javier Seoane , López Lourdes Martín de la Sierra , Evrard Eva Revuelta , Sánchez María Dolores Mínguez , Moya Elena Palacios , Degayon Elena Torres , Carrascosa Carlos Cebrián , Huertas Marcos Alfredo Paulino 
Published: July 2023

Abstract
Background A biosimilar is a biological medicine that contains a version of the active principle of a previously authorized original biological medicine (reference drug).Objective To evaluate the efficacy and safety of biosimilars in the treatment of immune-mediated inflammatory rheumatic diseases.Methods Retrospective observational and descriptive study of patients diagnosed with immune-mediated inflammatory rheumatic disease. Patients who had switched from a biological medicine to a biosimilar antiTNF and rituximab, for at least 24 weeks were included. Statistical tests such as the chi-square test were used to assess the independence of categorical variables, and Mann-Whitney U test was used to assess the independence between categorical and numerical variables, considering the heteroscedasticity of the groups.Results 364 patients who met the inclusion criteria were selected. 29.95% of patients discontinued treatment with the biosimilar: inefficacy in 87 patients (52 with primary failure and 35 with secondary failure), adverse effects in 18 patients and 4 patients discontinued it by their own decision. The mean disease activity at the beginning of the medication switch was 1.73 (± 0.93) in ASDAS, 8.73 (± 12.20) in DAPSA, and 2.60 (± 1.20) in DAS28, while at 24 weeks after the switch, the mean activity was 1.79 in ASDAS, 8.39 in DAPSA, and 2.62 in DAS28.Conclusions In our study, it was observed that 29.95% of the participants had to discontinue the use of the biosimilar drug, mainly due to its lack of efficacy, which exceeds the average reported in the current literature. Only 18 patients experienced some type of adverse effect, of which only 2 cases were severe. The mean activity levels measured by ASDAS, DAPSA, and DAS28 remained similar both at the beginning and at 24 weeks after the treatment switch, although patients with higher activity at the beginning of the switch presented higher activity levels at 24 weeks. Our data obtained in a real-life setting suggest that biosimilar drugs can be considered an effective and safe option in the treatment of inflammatory rheumatic diseases. However, it is important to note that there is a significant rate of discontinuation of biosimilar use.
Effectiveness of Recovery Strategies after Training and Competition in Endurance Athletes - an Umbrella Review
Authors: Li Shuting , Kempe Matthias , Brink Michel , Lemmink Koen 
Published: July 2023

Abstract
Background
Recovery strategies are used to enhance performance and reduce injury risk in athletes. In previous systematic reviews, individual recovery strategies were investigated to clarify their effectiveness for mixed groups of athletes. However, the current evidence is ambiguous, and a clear overview of (training) recovery for endurance athletes is still lacking.
Methods
We conducted an umbrella review based on a literature search in PubMed, Cochrane Database of Systematic Reviews, and Web of Science. Reviews published in English and before December 2022 were included. Systematic reviews and meta-analyses were eligible if they investigated the effectiveness of one or more recovery strategies compared with a placebo or control group after a training session in endurance athletes.
Results
Twenty-two reviews (nine systematic reviews, three meta-analyses, and ten systematic reviews with meta-analyses included) met the inclusion criteria. In total, sixty-three studies with 1100 endurance athletes were included in our umbrella review. Out of the sixty-three studies, eight provided information on training recovery time frame for data synthesis. Among them, cryotherapy and compression garments showed positive effects, while applying massage showed non-effect. In general, none of the included recovery strategies showed consistent beneficial effects for endurance athletes.
Conclusion
There is not a particular recovery strategy that can be advised to enhance recovery between training sessions or competitions in endurance athletes. However, individual studies suggest that compression garments and cryotherapy are effective training recovery strategies. Further research should improve methodology and focus on the different time courses of the recovery process.
Registration
The review protocol was registered with the International Prospective Register of Systematic Reviews with the number CRD42021260509.
Causal effects of Atorvastatin on the improvement of erectile dysfunction:A two-sample Mendelian randomization study
Authors: Yan Qingxin , Zhou Wenjing , Chen Yan , Zhu Yinghong 
Published: July 2023

Abstract
Background and aim: There are currently no clear conclusions about whether Atorvastatin can improve ED.In the study, we found the causal relationship between atorvastatin use and the improvement of erectile dysfunction by using Mendelian randomization (MR) analysis.
Methods: Single-nucleotide polymorphisms (SNPs) associated with atorvastatin use and erectile dysfunction were selected from the MRC IEU Open Genome Wide Association Study (GWAS) project.After standardized selection, the remaining SNPs were used as Instrumental variables estimation (IVs) of atorvastatin use for the following MR tests to evaluate the relationship between atorvastatin use predicted by genetics and the improvement of ED. In the study, the random-effect inverse-variance weighted (IVW) method was selected as the primary analysis. At the end of the study, Cochran's Q test,MR-Egger regression, funnel plots，Leave-one-out method and MR-pleiotropic residual sum and outlier were used for sensitivity analysis.
Results: Genetically predicted atorvastatin use was strongly associated with improvement in ED in the IVW analyses(OR = 23.91, 95% CI 1.57–364.25; p = 0.022). No evidence of pleiotropy, heterogeneity, or outlier single-nucleotide polymorphisms was found in the sensitivity analyses.
Conclusion: The results of this study found a causal relationship between atorvastatin use and the improvement of ED, providing evidence for clinical diagnosis and treatment.
Characteristics of bulk and monolayer VTe, including magnetic, phonon, and optical as affected by an electric field and biaxial strain
Authors: Jaafar. Mustafa M. , Al-zyadi Jabbar M. Khalaf 
Published: July 2023

Abstract
The generalized gradient approximation of density functional theory was employed to evaluate the electrical, magnetic, and optical characteristics of the bulk and monolayer phases of the zinc-blende VTe compound. According to phonon calculations, this compound is dynamically stable. The compound displays half metallicity in the bulk phase when the lattice constant is at equilibrium at 8.54 Å, in addition to a gap in the energy of 1.19 eV in the spin-down channel. It maintains the half-metallic property once transitioning to the monolayer with an assumed energy gap of 0.36 eV at the equilibrium lattice constant of 12.1 Å. The half-metallic property can still be preserved for strong strains. The electric fields have a considerable influence on the monolayer and a remarkable outcome on the size of the energy gap. Moreover, the optical characteristics of the spin channels have semiconductor properties and can be used in optoelectronic devices. The outcomes demonstrate that this compound has potential for use in spintronic applications.
Library resource library management based on modern information technology and reconfigurable mobile information systems
Authors: Zhang Fengbin 
Published: July 2023

Abstract
Library resource library management based on modern information technology and reconfigurable mobile information systems have attracted much attention from researchers of academia. As a typical application of reconfigurable mobile information systems, the construction of digital library, the introduction of computer automation technology into the field of library resource management, and the realization of automatic classification of book information are of great significance to the realization of digitalization and sharing of book resources. Library resource management is the one and complex tasks in library work. It has been done manually by book authors or book cataloguers for a long time. However, number of books has surged, and the domain knowledge involved in the books has become more and more extensive. It is impossible to manage the library resources manually. In the context of building a digital library, the introduction of computer automation technology into the field of library resource management to realize automatic classification of books and information, and is of great significance to the realization of digitization and sharing of book resources. They have been proven to be advantageous in various fields, including the field of natural language processing. This paper introduces the LSTM model into the field of Chinese library resource management, and tries to propose a classification system with practical application value. The main research work :The Chinese library resource is designed LSTM model, and three experiments are designed on this basis: the coarse-grained book single classification experiment, different measures on the classification results; the fine-grained book single classification experiment, to compare The advantages and disadvantages of direct classification and layer-by-layer classification; coarse-grained book multi-classification experiments to explore the feasibility of multi-classification. After analyzing the experimental results, the model has achieved a good classification effect, and overcomes some deficiencies in the library resource library predecessors, and has a strong practical application value.
Improvement studies for building capacity at Bali State Poly-technic
Authors: Suasira I Wayan , Suardika I Nyoman , Jaya I Made , Yuni Ni Kadek Sri Ebtha , Yuliana Ni Putu Indah 
Published: July 2023

Bali State Polytechnic has 6 majors, with 32 study programs. As many prospective students are interested in studying at the Bali State Polytechnic, it is not in line with the addition of classrooms. Until the 2021, PNB ideally needs 214 classrooms, while the number of available rooms is 142 classrooms. Thus PNB in 2021 still has a shortage of 72 learning rooms. In this study, a case study was taken in a Civil Engineering lecture building with a study of increasing space capacity through adding floors to existing buildings. The research was conducted by analyzing the strength of the building in terms of structure. The methods used are field studies and data analysis. Field studies are carried out through testing on the strength of existing structures, then from the results of field studies continued by analyzing additional designs. The capacity of the lecture building at the Bali State Polytechnic can be increased because the strength of the existing lecture building structure is able to bear the load due to the addition of space capacity from 2 floors to 3 floors.
IDENTIFIKASI JENIS JENIS MANGROVE DI PANTAI YA`ANG DESA LABUHAN KECAMATAN BRODONG KABUPATEN LAMONGAN
Authors: Raka  , Nor Sa’adah  , Perdana Ixbal Spanton M  , Amir Yarkhasy Yuliardi  
Published: July 2023

ABSTRAK
Kecamatan Brondong Kabupaten Lamongan memiliki banyak jenis mangrove di wilayah pesisi pantai dan memiliki garis pantai mencapai 47 km Kabupaten Lamongan dan wilayah hutan mangrove sekitar 53.37 Ha. Penelitian ini ditujukan untuk mengetahui jenis-jenis dan ciri-ciri mangrove. Metode yang digunakan yaitu survey eksploratif. Hasil Penelitian menunjukkan hasil bahwa Kecamatan Brodong Kabupaten Lamongan memiliki berbagai jenis- jenis mangrove sebanyak 6 jenis mangrove terdiri atas Avicennia marina, Avicennia alba, Rhizopora mucronata Rhizopora stylosa, Bruguiera gymnorrhiza, Sonneratia alba.
Kata Kunci : Jenis Mangrove, ciri ciri mangroe, Ekosistem Mangrove
ВИМІРЮВАННЯ ВИКИДІВ NOх ГАЗОВИХ КОТЛІВ
Authors: ІВАСЕНКО Віталій 
Published: July 2023

Розглянуто проблему контролю та максимальної ефективності роботи паливовикористовуючого обладнання (котли), що працюють на природному газу. Cеред токсичних газів, що містять димові гази енергетичних об’єктів (ТЕЦ, котельні), значне місце посідають оксиди азоту (NO, NO2, NOx). Аналіз відхідних газів дозволяє визначити концентрацію забруднюючих речовин і максимально налаштувати оптимальну роботу обладнання, досягнувши скорочення викидів та відповідність затвердженим державним екологічним нормам. Шляхом до оптимальної роботи обладнання є встановлення об’єму повітря, що подається на горіння. Все це потребує використання інструментального контролю (газоаналізаторів). Розглянуто принципи єдності вимірювання, що включають в себе подання результатів вимірювання в стандартних одиницях (ppm, мг/м3). Наведено перерахунок з об’ємної концентрації (ppm) в масову (мг/м3). Також необхідність вимірювання вмісту кисню у відхідних димових газах при перерахунку значень концентрацій з «ppm» в «мг/м3», для паливовикористовуючого обладнання. Розглянуто принципи виробу місця для проведення вимірювання концентрацій та параметрів відхідних газів. Виконання цих умов дозволяє підвищити точність вимірювання. Проведені вимірювання концентрації оксидів азоту, в перерахунку на діоксид азоту в залежності від надлишку кисню в паливовикористовуючому обладнанні. Досліджено утворення концентрації оксидів азоту, в перерахунку на діоксид азоту в залежності від навантаження при різних значеннях теплопродуктивності котла, що працює на природному газу. Розглянуті додаткові фактори (вологість та надлишку кисню), які можуть впливати на результати вимірювання викидів паливовикористовуючого обладнання. Обґрунтовано використання газоаналізаторів з одночасним вимірюванням оксидів азоту та кисню у вихідних димових газах для контролю дотримання нормативних викидів та ефективної роботи паливовикористовуючого обладнання.