bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors and Surgical Site Infection in Patients with Surgical Antibiotic Prophylaxis in the Indian Population: A Prospective Cohort Study
Authors: Sankar Karthik , Anbalagan Deepika , Baskaran Balaswetha , Segaran Vysali , Prabakar Yogitha , Raghu Sridhar , Krishna Vidhya , Singaram Venkatesan , Santhiyagu Xavier , Rajanandh Muhasaparur Ganesan 
Published: July 2023

Objective: To assess the risk factors and Surgical Site Infections (SSI) in patients with surgical antibiotic prophylaxis (SAP) within the Indian population. Material and Methods: A prospective cohort study, consisting of 1,362 patients, with the age of 18 and above; admitted for various surgical procedures, and prescribed with SAP were included. In order to determine the significance of categorical data, the chi-square test, and Multiple binary logistic regression via the backward wald method was used to identify the risk factors. Various risk factors and their association to SSI were assessed, with a probability value of ≤0.05 being considered as a significant level. Result: In total, 171 SSI were observed; with an incidence of 12.6% [95% CI=11.1-16.6] among all study patients (1,362). Cefotaxime was the most prescribed SAP in this study. In total 59.6% had gram-positive organisms and 40.4% had gram-negative organisms. Type of surgery, female gender, smoking and alcohol, diabetes with hypertension, microbial growth, American Society of Anesthesiologists (ASA) score (class III), hospital guidelines, and pre-operative hospital stays (>7 days) were the significant risk factors (p-value<0.05) associated with SSI. There was no significant association with drain use, nor redosing (p-value>0.05). Conclusion: This study emphasizes the significant risk factors; such as age, female gender, types of surgery, ASA score, nonadherence to hospital guidelines, monomicrobial and polymicrobial growth and poor compliance to SAP being associated with SSI in surgical patients. These risk factors allow a better understanding related to SSI, which may have therapeutic implications.
Systematization of Cyber Threats in Maritime Transport
Authors: Polikarovskykh Oleksiy , Daus Yurii , Larin Dmytro , Tkachenko Mariia 
Published: July 2023

The paper proposes a classification of cyber-attacks at the present stage of maritime transport development. A classification system for ship blocks and port infrastructure has been developed. The vulnerabilities of the global navigation satellite system are analyzed; this system is the most important subcategory of maritime vehicles and may be a target for cyber-attacks. The paper shows that the rapid spread of cybercrime occurs due to the rapid development of new technologies and their integration into ship and port infrastructures. The main elements of the maritime transport infrastructure are considered: port infrastructure and ship infrastructure. IoT and Big Data can be examples of the spread of such systems. The ship's IT infrastructure, ship's electromechanical and electronic systems, communication systems, automatic identification systems, ship information system are considered. In the port infrastructure, port security systems, port equipment systems, port communication systems are analyzed. The main types of cyber-attacks to which the ship and port parts of the industry are exposed are considered. The signs of attacks on the Internet of things systems on ships and in ports are considered. The trend towards greater system integration cannot be reversed for economic reasons. Such integration makes it possible to reduce the size of the team, build autonomous ships, work in the smart ports system, and makes it possible to save various resources (time, human, fuel and organizational). The paper considers the practical directions and challenges facing the industry in terms of improving the security of maritime transport in cyberspace.
Relationships between technological and nutritional meat quality traits in native Mexican Guajolote (M. g. gallopavo)
Authors: Portillo Salgado Rodrigo , Herrera Haro José Guadalupe , Bautista Ortega Jaime , Cigarroa Vázquez Francisco Antonio 
Published: July 2023

Objective: To evaluate the relationships between some technological and nutritional meat quality traits in native Mexican Guajolote (M. g. gallopavo).
Design/methodology/approach: In the study, a total of 35 carcasses from male native guajolotes (32-40 weeks old; approximately 2.9 kg carcass weight) were used. Some technological [pH, colour (L*, a*, b*), water-holding capacity (WHC), drip loss (DP), and cooking loss (CL)] and nutritional [dry matter (DM), crude protein (CP), crude fat (CF), crude ash (CA) and energy content (EC)] properties of breast and leg meat were evaluated. Pearson correlation of SAS software was used for data analysis.
Results: In breast meat, moderate to high positive correlations (P < 0.01; 0.35 [pH45min vs pH24h] ≤ r ˂ 0.82 [DM vs EC]) were observed, but highly and negatively correlations (P < 0.01; -0.36 [CF vs CA] ≤ r < -0.77 [b* vs DL]) also were found. Similarly, technological and nutritional quality traits in leg meat also showed moderate to high positive correlations (P < 0.01; 0.38 [pH24h vs L*] ≤ r < 0.74 [DM vs CF]); however, high negative correlations (P < 0.01; -0.42 [pH24h vs CL] ≤ r < -0.69 [a* vs b*]) were observed.
Limitations on study/implications: Studies on the factors that affect the technological and nutritional characteristics of meat quality in this poultry species should be carried out
Findings/conclusions: The results could be used as an important benchmark of the current state of Guajolote meat quality to develop selection and breeding programs in its genetic improvement.
Bentuk dan Konstruksi Pendidikan Politik pada Organisasi Mahasiswa Kesatuan Aksi Mahasiswa Muslim Indonesia (KAMMI) dan Ikatan Mahasiswa Muhammadiyah (IMM) di Kota Pangkalpinang
Authors: Pratama Imam Alfikri 
Published: July 2023

This study aimed to find out how, what kind of ways, methods and the political education basic conducted and how the role of political education conducted KAMMI and IMM student organizations in PangkalpinanG. This study used a qualitative approach with descriptive study method. Data collection techniques used were interviews, observation, documentation studies and literature studies. The results revealed that student KAMMI and IMM in Pangkalpinang looked at education as an effort to build political understanding in the context of civilization politics. Besides, the political education could establishing student leadership in managing student organizations. The ways for creating political education are through political education cadre, and training organization; The methods used are training, self-learning, study material, internal discussions and public discussion on the organization.

Keywords: Political Education, Student Organization
Investigasi Etnomedisin pada Masyarakat Desa Blang Pase, Kota Langsa, Aceh
Authors: Wijaya Gadis Arsinta , Nurjannah Nurjannah , Rezeki Juli Trianda Sri , Fijannah Reva Riski , Navia Zidni Ilman 
Published: July 2023

Etnobotani pemanfaatan tumbuhan sebagai obat tradisional sudah dikenal sejak lama oleh masyarakat khususnya masyarakat Blang Pase Kota Langsa dan diwariskan secara turun-temurun, namun semakin berkembangnya zaman diera modern tradisi ini mulai menurun. Tujuan dari penelitian ini adalah untuk mengetahui jenis-jenis tumbuhan yang dimanfaatkan oleh masyarakat Desa Blang Paseh Kecamatan Langsa Kota, cara pemanfaatan tumbuhan obat, dan bagian tumbuhan mana saja yang dimanfaatkan untuk obat. Penelitian ini dilaksanakan pada 15 November hingga 30 Desember 2021 di 5 Dusun, Penelitian Ini dilakukan secara deskriptif eksploratif dengan teknik survei, wawancara semi terstruktur dan Kuisioner. Analisis data dilakukan menggunakan Use value (UV), dimana setiap jenis tumbuhan obat dihitung berdasarkan rumus Phillips dan Gentry. Berdasarkan hasil penelitian, diketahui terdapat 14 spesies yang dimanfaatkan sebagai obat tradisional. Bagian tumbuhan yang dominan digunakan sebagai obat yaitu daun 42% dan jenis tumbuhan obat yang telah dibudidayakan sebesar 85.7%. Tumbuhan yang memiliki nilai UV tertinggi dan responden terbanyak adalah Zingiber officinale Roscoe dengan nilai UV 0.7.
Pengaruh Model Pembelajaran Generatif pada Pembelajaran Biologi Materi Sistem Indra Berbasis Qur’ani terhadap Hasil Belajar Siswa
Authors: Ujung Pajar Ainun , Rasyidah  , Syahputra Irwan 
Published: July 2023

Model pembelajaran generatif memfokuskan pada peran aktif peserta didik dalam memecahkan masalah dengan membangun pengetahuan lama dengan pengetahuan baru. Dalam mempelajari sistem indera berbasis Al-Qur'an dapat dilakukan dengan memadukan teori dengan nilai-nilai dalam Al-Qur'an untuk menciptakan sensibilitas Islami. Metode penelitian yang digunakan adalah Quasi Experiment yang dilakukan di MAN Dairi pada Januari 2022 dengan populasi 92 siswa yang terdiri dari dua kelas dengan sampel purposive sampling dimana menggunakan kelas eksperimen dan kelas kontrol.Hasil belajar biologi materi sistem indra berbasis Qur`ani siswa kelas eksperimen (XI IPA-1) dengan menggunakan model generatif diperoleh nilai rata-rata 82,33 sedangkan kelas kontrol (XI IPA-3) dengan menggunakan model konvensional diperoleh nilai rata-rata 75,63. Berdasarkan hasil belajar siswa terdapat pengaruh penggunaan model pembelajran generatif pada proses pembelajaran dan hasil belajar. Sehingga dapat disimpulkan bahwa model pembelajaran generatif berbasis Qur’ani dapat meningkatkan hasil belajar siswa
Empleabilidad de los terapeutas respiratorios egresados de la Facultad de Ciencias de la Salud de la Fundación Universitaria del Área Andina, Pereira, Risaralda, 2021
Authors: Blanco Vanegas Angélica María , Cardona José Gerardo , Rojas Galvis Santiago 
Published: July 2023

La terapia respiratoria (TR) es una profesión vital para los servicios asistenciales hospitalarios. Esta es una disciplina básica dentro del equipo médico e impacta positivamente el estado de salud de los pacientes en las diferentes patologías cardiorrespiratorias mediante la aplicación de diversas modalidades de intervención11. El área de terapia respiratoria se ha expandido y ha impactado a la sociedad con la implementación de sus conocimientos y diversos procedimientos clínicos con el fin de ofrecer una adecuada atención en salud a los pacientes2. Actualmente, la legislación nacional y los requerimientos de los profesionales especializados en el cuidado respiratorio toma fuerza no solo por las demandas del mercado sino también por el aporte que estos generan en la atención y reducción de costos a un sistema de salud en crisis3. Objetivo: identificar la empleabilidad de los terapeutas respiratorios en Pereira, Risaralda, 2021. Materiales y métodos: la investigación observacional, descriptiva con enfoque cuantitativo, la evaluación de las variables reportadas de una encuesta anónima realizada por la oficina de egresados de la Fundación Universitaria del Área Andina, aplicada a 135 egresados del programa de Terapeutas Respiratorios de la sede Pereira. La captura y procesamiento básico de información según las variables del estudio se hizo a través de Excel y el programa SPSS. Resultados: se pudo apreciar que, de un total de 135 egresados, 117 que corresponden al 86 % de la población, manifestaron que se encuentran laborando como terapeutas respiratorios actualmente; solo el 6,6 % (9 personas) reportan estar desempleados y los demás registran ocupaciones laborales tales como independientes, empresarios y trabajos fuera del país. Conclusiones: este estudio evidencia la necesidad de realizar nuevas investigaciones sobre este campo ocupacional, además se confirmaron cambios en el perfil ocupacional a causa del SARS-CoV-2.
An Observational Study on Levels of Serum Fibrin Degradation Product (FDP), D-Dimer and Procalcitonin in Burn Sepsis
Authors: Begum Nurunnahar , Hasan Mahbub , Ahmed Tanveer , Kalam Md Abul 
Published: July 2023

Background: Despite improvements in burn management, infection is still the biggest challenge in major burn cases globally. Burn causes extensive tissue destruction, immune dysfunction, increases the risk of infection and septicemia with high morbidity and mortality. The aim of this study was to observe the levels of serum fibrin degradation product (FDP), D-dimer and procalcitonin in patients with burn sepsis treated in intensive care unit (ICU).
Materials & Methods: This observational study was carried out in Department of Burn and Plastic Surgery, Dhaka Medical College Hospital, Dhaka from February 2018 to January 2019. Forty (40) patients with major burns, from (15% to 50% total body surface area burn) with burn sepsis, were recruited for the study. In all cases, plasma level of fibrin degradation product (FDP), D-dimer and procalcitonin were measured and recorded.
Result: Male predominance (57.5%) was observed in our study. Eighty five percent (85%) patients had total body surface area burn (TBSA) 20% to 50%. Sixteen patients (40%) suffered from flame burn, 13 (32.5%) patients from scalds and 11 (27.5%) patients had high voltage electric burn. The value of FDP was raised in 62.5% patients, D- dimer in 67.5% patients. Serum procalcitonin level was high (> 2ng/ml), indicating burn sepsis in 47.5% cases but it was not significant (2 sample t – test reveals no significant relationship between rise of serum level of procalcitonin and presence of burn sepsis)
Conclusion: Fibrin degradation product (FDP) and D- dimer were raised in two-thirds of burn cases while procalcitonin in two-fifths cases. Measurement of serum level of FDP, Ddimer and procalcitonin may give an idea regarding early onset of bacterial infection and burn sepsis and can serve as an indicator for burn sepsis.
J Bangladesh Coll Phys Surg 2023; 41: 193-197
Literature and Medicine in the Nineteenth-Century Periodical Press
Authors: Coyer Megan 
Published: July 2023

In the early nineteenth century, Edinburgh was the leading centre of medical education and research in Britain. It also laid claim to a thriving periodical culture. Literature and Medicine in the Nineteenth-Century Periodical Press investigates how Romantic periodicals cultivated innovative literary forms, ideologies and discourses that reflected and shaped medical culture in the nineteenth century. It examines several medically-trained contributors to Blackwood's Edinburgh Magazine, the most influential literary periodical of the time, and draws upon extensive archival and bibliographical research to reclaim these previously neglected medico-literary figures. Situating their work in relation to developments in medical and periodical culture, the book advances our understanding of how the nineteenth-century periodical press cross-fertilised medical and literary ideas. In the case of Blackwood’s, it is argued that the magazine’s distinctive Romantic ideology and experimental form enabled the development of an overtly ‘literary’ and humanistic popular medical culture, which participated in a wider critique of liberal Whig ideology in post-Enlightenment Scotland.
Preliminary landscape of Candidatus Saccharibacteria in the human microbiome
Authors: Naud Sabrina , Valles Camille , Abdillah Abdourahim , Abou Chacra Linda , Mekhalif Fatima Zouina , Ibrahim Ahmad , Caputo Aurelia , Baudoin Jean-Pierre , Gouriet Frédérique , Bittar Fadi , Lagier Jean-Christophe , Ranque Stéphane , Fenollar Florence , Tidjani Alou Maryam , Raoult Didier 
Published: July 2023

IntroductionCandidate Phyla Radiation (CPR) and more specifically Candidatus Saccharibacteria (TM7) have now been established as ubiquitous members of the human oral microbiota. Additionally, CPR have been reported in the gastrointestinal and urogenital tracts. However, the exploration of new human niches has been limited to date.MethodsIn this study, we performed a prospective and retrospective screening of TM7 in human samples using standard PCR, real-time PCR, scanning electron microscopy (SEM) and shotgun metagenomics.ResultsUsing Real-time PCR and standard PCR, oral samples presented the highest TM7 prevalence followed by fecal samples, breast milk samples, vaginal samples and urine samples. Surprisingly, TM7 were also detected in infectious samples, namely cardiac valves and blood cultures at a low prevalence (under 3%). Moreover, we observed CPR-like structures using SEM in all sample types except cardiac valves. The reconstruction of TM7 genomes in oral and fecal samples from shotgun metagenomics reads further confirmed their high prevalence in some samples.ConclusionThis study confirmed, through their detection in multiple human samples, that TM7 are human commensals that can also be found in clinical settings. Their detection in clinical samples warrants further studies to explore their role in a pathological setting.
Ground subsidence associated with mining activity in the Ningdong coal base area, northwestern China revealed by InSAR time series analysis
Authors: Tang Wei , Wang Mingliang , Li Peixian , Wang Guorui , Yan Yueguan , Yan Weitao 
Published: July 2023

Ningdong coal base area located in northwestern China is one of the largest coal-producing bases in China. The aim of this work is to investigate a regional-scale mining subsidence over the Ningdong coal base area, by using both conventional and advanced Differential Synthetic Aperture Radar Interferometry (DInSAR) methods. Fifteen L-band SAR images from ALOS-2 satellite and 102 C-band images from Sentinel-1A satellite spanning between November 2014 and July 2019 were used for the analysis. To increase the spatial extent of the displacement signal because of decorrelated effects, we modified the traditional Small Baseline Subset (SBAS) method to incorporate the coherence into the inverse problem, hereafter we call it coherence-based SBAS method. Instead of excluding decorrelated pixels present in the interferograms, we keep all the pixels in the time series analysis and down-weighted the decorrelated pixels with coherence. We performed the coherence-based SBAS method to both the two SAR datasets to obtain the subsidence rate maps and displacement time-series over the mining areas, and compared the results with that from the traditional stacking InSAR method. We evaluated the effectiveness of L-band and C-band DInSAR for monitoring mining subsidence by comparing differential interferograms and displacements derived from SBAS method between ALOS-2 and Sentinel-1A data. Compared to C-band, L-band SAR are less affected by phase aliasing due to large displacement gradients. The most significant subsidence was found at Maliantai mine with −264 mm/year detected by SBAS method from Sentinel-1 data. We validated the InSAR displacement accuracy by comparing both ALOS-2 and Sentinel-1 results with 18 GPS stations above five active mining regions. The average RMSE between InSAR and GPS measurements is 28.4 mm for Sentinel-1 data and 21 mm for ALOS-2 data. Our results demonstrate that the combined exploitation of L-band and C-band SAR data through both conventional and advanced DInSAR methods could be crucial to monitor ground subsidence in mining areas, which provides insights into subsidence dynamics and determine the characteristic surface response to longwall advance.
Causality between inflammatory bowel disease and the cerebral cortex: insights from Mendelian randomization and integrated bioinformatics analysis
Authors: He Shubei , Peng Ying , Chen Xiaofang , Ou Ying 
Published: July 2023

BackgroundInflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic, progressive, and recurrent intestinal condition that poses a significant global health burden. The high prevalence of neuropsychiatric comorbidities in IBD necessitates the development of targeted management strategies.MethodsLeveraging genetic data from genome-wide association studies and Immunochip genotype analyses of nearly 150,000 individuals, we conducted a two-sample Mendelian randomization study to elucidate the driving force of IBD, UC, and CD on cortical reshaping. Genetic variants mediating the causality were collected to disclose the biological pathways linking intestinal inflammation to brain dysfunction.ResultsHere, 115, 69, and 98 instrumental variables genetically predicted IBD, UC, and CD. We found that CD significantly decreased the surface area of the temporal pole gyrus (β = −0.946 mm2, P = 0.005, false discovery rate-P = 0.085). Additionally, we identified suggestive variations in cortical surface area and thickness induced by exposure across eight functional gyri. The top 10 variant-matched genes were STAT3, FOS, NFKB1, JAK2, STAT4, TYK2, SMAD3, IL12B, MYC, and CCL2, which are interconnected in the interaction network and play a role in inflammatory and immune processes.ConclusionWe explore the causality between intestinal inflammation and altered cortical morphology. It is likely that neuroinflammation-induced damage, impaired neurological function, and persistent nociceptive input lead to morphological changes in the cerebral cortex, which may trigger neuropsychiatric disorders.
Unveiling efferocytosis-related signatures through the integration of single-cell analysis and machine learning: a predictive framework for prognosis and immunotherapy response in hepatocellular carcinoma
Authors: Liu Tao , Li Chao , Zhang Jiantao , Hu Han , Li Chenyao 
Published: July 2023

BackgroundHepatocellular carcinoma (HCC) represents a prominent gastrointestinal malignancy with a grim clinical outlook. In this regard, the discovery of novel early biomarkers holds substantial promise for ameliorating HCC-associated mortality. Efferocytosis, a vital immunological process, assumes a central position in the elimination of apoptotic cells. However, comprehensive investigations exploring the role of efferocytosis-related genes (EFRGs) in HCC are sparse, and their regulatory influence on HCC immunotherapy and targeted drug interventions remain poorly understood.MethodsRNA sequencing data and clinical characteristics of HCC patients were acquired from the TCGA database. To identify prognostically significant genes in HCC, we performed the limma package and conducted univariate Cox regression analysis. Subsequently, machine learning algorithms were employed to identify hub genes. To assess the immunological landscape of different HCC subtypes, we employed the CIBERSORT algorithm. Furthermore, single-cell RNA sequencing (scRNA-seq) was utilized to investigate the expression levels of ERFGs in immune cells and to explore intercellular communication within HCC tissues. The migratory capacity of HCC cells was evaluated using CCK-8 assays, while drug sensitivity prediction reliability was determined through wound-healing assays.ResultsWe have successfully identified a set of nine genes, termed EFRGs, that hold significant potential for the establishment of a hepatocellular carcinoma-specific prognostic model. Furthermore, leveraging the individual risk scores derived from this model, we were able to stratify patients into two distinct risk groups, unveiling notable disparities in terms of immune infiltration patterns and response to immunotherapy. Notably, the model’s capacity to accurately predict drug responses was substantiated through comprehensive experimental investigations, encompassing wound-healing assay, and CCK8 experiments conducted on the HepG2 and Huh7 cell lines.ConclusionsWe constructed an EFRGs model that serves as valuable tools for prognostic assessment and decision-making support in the context of immunotherapy and chemotherapy.