bluuebunny/crossref_metadata_2025_split huggingface dataset:
Krónikus pancreatitis miatt végzett pancreasfej-resectiós műtéteink elemzése
Authors: Kelemen Dezső , Deák Rita , Ferencz Sándor , Farkas Nelli , Horváth Örs Péter , Vereczkei András 
Published: September 2023

BevezetésA krónikus pancreatitisnek gyulladásos pancreasfej-megnagyobbodással járó formájában a sebészi kezelésre többféle beavatkozás is kínálkozik, úgymint a Beger-, Frey-, Whipple-műtét és a berni módosítás. Jelen tanulmány az ezekkel elért eredményeket hasonlítja össze, továbbá a pancreatojejunalis és biliodigesztív anastomosis terén végzett innovációkat is ismerteti.Anyag és módszerek1991 és 2021 között összesen 231 pancreasfej resectiót végeztünk. Az adatokat retrospektíven elemeztük. Kérdőívek útján vizsgáltuk a késői eredményeket is. Eredmények: A statisztikai feldolgozás alapján a berni módosítás és a Frey-műtét előnyösebbnek bizonyult a Whipple- és a Beger-műtétnél az operáció időtartama és a transzfúziós igény (P < 0,001) tekintetében, míg az intenzív osztályos és teljes posztoperatív ápolási idő (P < 0,001) terén a Whipple-műtéthez viszonyítva voltak kedvezőbbek. A korai morbiditás gyakorisága a Whipple-műtétet követően volt a legnagyobb (P = 0,004). Ezek a különbségek szignifikánsak voltak. A reoperáció és a mortalitás aránya hasonló volt a csoportokban. A betegek életminősége elfogadható volt, annak ellenére, hogy az esetek zömében az alkohol és nikotin abúzus megmaradt.KövetkeztetésA Frey-műtét és a berni módosítás volt a legkedvezőbb a korai posztoperatív kimenetel szempontjából, technikailag egyszerűbb volta miatt viszont inkább az utóbbi beavatkozást részesítjük előnyben. Mindkét műtét során a pancreatojejunalis anastomosis készítésére egyrétegű tovafutó varratot, és epepangás esetén annak megoldására egy extrapancreaticusan végzett biliodigesztív összeköttetés létesítését ajánljuk a kedvező tapasztalatok alapján.
Transmesenteriális colon átvezetéses colorectális anasztomózis
Authors: Szabó Károly , Bezsilla János 
Published: September 2023

BevezetésA colorectalis műtétek legfontosabb eleme a megfelelő bélösszeköttetés elkészítése. A varratelégtelenség elkerüléséhez többek között két alapvető tényező szükséges: az anasztomizált bélvégek megfelelő vérellátása, valamint a feszülésmentes varratsor. Kiterjesztett bal oldali vastagbél-resectiók után előfordulhat, hogy a hagyományos módon mobilizált colon feszülésmentesen nem köthető össze a rectumcsonkkal. Ezekben az esetekben javasolják a colon transversum transmesenterialis úton történő levezetését a kismedencébe.MódszerA BAZ Megyei Központi Kórház és Egyetemi Oktatókórház Sebészeti Osztályán végzett transmesenterialis colon átvezetéses colorectalis anasztomózisok eredményeit prezentáljuk, összevetve az irodalmi adatokkal.EredményekNyolc betegnél alkalmaztunk transmesenterialis colon átvezetéses colorectális anasztomózist. Varratelégtelenséget nem észleltünk. Az intraoperatív vérveszteség, intra- és posztoperatív fájdalomcsillapítás, bélműködés beindulása hasonló módon alakult, mint a hagyományos anasztomózisok esetében várható. Öt betegnél laparoszkóposan, három esetben laparoszkópia után conversio során készült el az anasztomózis.KövetkeztetésA bal oldali colonfelet és rectosigmoideális szakaszt érintő kiterjesztett resectiók során előfordulhat, hogy nem megfelelő az anasztomizálni kívánt bélvég hossza. Amikor a mobilizált colon a hagyományos teljes mobilizálást követően sem ér le feszülésmentesen a kismedencébe, alkalmazható a transmesenteriálisan átvezetett colon transversummal történő bélvarrat. Ez a laparoszkóppal is végezhető módszer biztonságos alternatíva lehet a feszülésmentes anasztomózis elkészítésében.
Utilidad de la espirometría en los pacientes hospitalizados por la enfermedad pulmonar obstructiva crónica (EPOC) exacerbada
Authors: Hernández-Ruiz Alfredo , Ortega Héctor José , Aguirre-Acevedo Daniel Camilo 
Published: September 2023

La espirometría es la prueba estándar para confirmar el diagnóstico de la enfermedad pulmonar obstructiva crónica (EPOC). En los servicios de hospitalización es frecuente encontrar pacientes que ingresan con sospecha de esta condición durante una exacerbación. Con base en las guías actuales, existe controversia sobre si se puede o no realizar la espirometría en este escenario.
Objetivo: revisar la utilidad diagnóstica de la espirometría en pacientes hospitalizados con sospecha de EPOC exacerbada.
Metodología: se realizó una revisión no sistemática hasta noviembre del 2019. Las bases de datos consultadas fueron PubMed, Cochrane, EMBASE, LILACS, Google Scholar. Se incluyeron estudios prospectivos en pacientes mayores de 18 años, en idioma inglés y español. Se encontraron 573 artículos y se seleccionaron 20 artículos de relevancia para la discusión.
Conclusiones: en los pacientes hospitalizados por sospecha de EPOC exacerbada, la espirometría es una herramienta útil para confirmar el diagnóstico. El momento para realizarla es previo al egreso, una vez el paciente está estable. Anotamos que el VEF1 no sería útil para establecer la gravedad.
Cetoacidosis diabética: características epidemiológicas y letalidad en adultos atendidos en un hospital universitario en Colombia
Authors: Sierra-Vargas Elsy Cristina , Muñoz-Mejía Óscar Arlex , Zamudio-Burbano Miguel Ángel , Gómez-Corrales Juan David , Builes-Barrera Carlos Alfonso , Román-Gónzález Alejandro 
Published: September 2023

Introducción: la cetoacidosis diabética es una de las complicaciones agudas más graves de la diabetes. Pocos estudios en Latinoamérica describen el perfil clínico y los desenlaces de la población adulta con esta condición. El objetivo de este estudio es determinar las características demográficas y clínicas de los pacientes adultos con esta enfermedad. Para esto se hizo énfasis en los factores precipitantes y en la determinación del porcentaje de letalidad intrahospitalaria por cualquier causa.
Métodos: estudio de cohorte retrospectivo de pacientes mayores de 18 años admitidos por cetoacidosis diabética en el Hospital Universitario San Vicente Fundación de Medellín-Colombia, entre enero de 2012 y diciembre de 2015.
Resultados: se incluyeron 159 pacientes con diagnóstico de cetoacidosis diabética. La mediana de la edad fue de 46 años. 40 individuos (25,2 %) tenían diabetes tipo 1, 107 (67,3 %) diabetes tipo 2 y, 12 (7,6 %), otro tipo de diabetes. El factor precipitante de cetoacidosis diabética más común fue la suspensión del tratamiento hipoglucemiante (36 %), seguida de infección (32 %) y diabetes de novo (28 %). La mediana de la estancia hospitalaria fue de 8 días. 12 pacientes fallecieron.
Conclusión: la evaluación de los casos de cetoacidosis diabética en este estudio demostró diferencias importantes en la presentación clínica de aquellos con diabetes tipo 1 y tipo 2. La suspensión del tratamiento fue el factor precipitante más frecuente, seguido por la infección. La letalidad en este estudio fue de 7,5 %, superior a la tasa de 1 % que tienen los países desarrollados, evidenciando la necesidad de mejorar la atención de estos pacientes.
Clinical and epidemiological characteristics of pediatric patients with post-traumatic open globe injury
Authors: YILDIRIM BİÇER Gamze , ZOR Kürşad Ramazan 
Published: September 2023

Purpose: The aim of this study was to determine the epidemiology and clinical features of pediatric traumatic open globe injuries in our region.
Materials and Methods: Medical records of patients under the age of 18 who were diagnosed with open globe injury between January 2012 and December 2022 were retrospectively reviewed. Demographic data of the patients such as age, gender, time of injury, area of injury, type of injury, and cause of injury were recorded. Initial and final visual acuity and ocular findings at admission were recorded. Factors associated with final visual acuity were evaluated.
Results: The mean age of the patients was 7.62 ±4.22 years. The majority of the patients were male (n=28, 66,7%). The right eye was the most injured (n=30, 71.4%). The initial visual acuity of approximately 72.5% (n=29) of the patients was worse than 20/200. And the final visual acuity of 50% of the patients (n=20) was below 20/200. The most common type of injury was penetrating trauma (n=18, 42.9%). The region with the highest trauma was Zone I (n=30, 71.4%). The most traumatic materials were metallic objects (n=13, 31%). The most common accompanying clinical finding was lens damage (n=18, 42.9%). Iris damage, lens damage, hyphema, vitreous hemorrhage, retinal detachment, endophthalmitis, type of injury, material causing the injury, and injury area were significantly associated with final vision.
Conclusion: In our region, open globe injuries were mostly observed in boys under 12 years in the pediatric age group. Penetrating and cutting metallic objects seem to be the most important cause of trauma. Parents and all caregivers should be informed of the seriousness of open globe injuries to prevent possible injuries.
Comparison of visceral adipose tissue in patients with autonomous cortisol secretion and patients with the nonfunctional adrenal masses
Authors: PİŞKİN Ferhat Can , ODABAŞ Fulya , AKSOYDAN Ulcaz Perihan , AKKUŞ Gamze 
Published: September 2023

Purpose: This study aimed to explore the impact of continuous autonomous cortisol secretion on visceral (VAT), abdominal subcutaneous (SAT) adipose tissue, and total body fat.
Materials and Methods: A total of 57 patients (36 female, 21 male) with adrenal masses, referred to our single center, were included in this study. Among them, 31 patients had adrenal cortical carcinoma (ACS) and 26 had nonfunctional adrenal mass (NFAM). Hormonal evaluation was conducted for all patients. Measurements of total, visceral, and subcutaneous adipose tissue were performed using 3.0 T magnetic resonance imaging (Ingenia, Philips Medical Systems, Best, The Netherlands).
Results: Mean age, gender distribution, and body mass index (BMI) were comparable between patients with ACS and NFAM. Patients with ACS exhibited higher volumes of both total (422.1±131.3 vs. 346.2±86.0 cm3) and visceral adipose tissue (199.9±77.3 vs. 160.6±60.8 cm3) compared to those with NFAM. Incidence rates of diabetes mellitus and hepatosteatosis were similar in both groups. Subcutaneous adipose tissue volumes, visceral-to-subcutaneous ratio, and visceral-to-total fat ratio showed no significant differences between the two groups.
Conclusion: Patients with ACS demonstrated increased total and visceral fat tissue volumes compared to NFAM patients matched for gender, age, and BMI. This observation may elucidate the potential influence of continuous mild autonomous cortisol secretion in ACS patients. Such findings could serve as indicators of heightened cardiovascular risk among ACS patients.
Evaluation of six radiomorphometric indices
Authors: Mosavat Farzaneh , Sinanoglu Alper , Khodadadi Zahra , Sabzevari Zahra Sadeghi 
Published: September 2023

Purpose: Aging is accompanied by the gradual loss of teeth, which can cause several orofacial changes. This study aimed to compare panoramic radiomorphometric indices between dentate and totally edentulous patients.
Materials and Methods: One hundred panoramic radiographs were analyzed to measure six indices using Clinview 9.3 software: the gonial angle (GA), antegonial angle (AGA), condylar height (CH), ramus height (RH), mental index (MI), and mandibular cortical index (MCI). An independent sample t-test and Chi-square was used to compare the means of the measured data between dentate and edentate subjects and genders.
Results: In both genders, dentate people had greater left CH (p=0.05) and left GA (p=0.03). Men had greater RH in the dentate and edentate groups (p<0.001). No correlation was found between groups and genders in MCI scores.
Conclusion: CH index assessment as the function of the masticatory muscles and GA as residual ridge resorption were decreased in edentulous people. The findings highlight the importance of oral hygiene education and prosthetic rehabilitation of the edentulous.
Patrimonio arqueológico en perspectiva: alcances de un siglo formativo en la modernidad del Perú republicano
Authors: Uribe Claudia 
Published: September 2023

El presente artículo discute la construcción de la noción de patrimonio arqueológico desde el Perú del siglo XIX, en el marco de los procesos históricos y sociopolíticos relativos a su formación como estado-nación moderno. Frente a la concentración de reflexiones sobre el origen de los fundamentos y las praxis patrimoniales en la intersección de la arqueología peruana y el nacionalismo en los inicios del siglo XX, este estudio argumenta que dicho periodo marca un hito trascendental en el devenir de una serie de procesos que inician en el Perú decimonónico. Bajo la perspectiva del patrimonio como una construcción social y como proceso, se propone que este atraviesa por un siglo formativo desde los primeros años de la era republicana a partir de tres ejes: el nacionalismo, la perspectiva científica moderna y las instituciones tutelares. Este estudio concluye identificando dos momentos críticos y fundacionales del patrimonio arqueológico en contextos de efervescencia nacionalista estimulados por las élites políticas e intelectuales: el surgimiento del Estado peruano (1821- 1824) y los años posteriores a la Guerra del Pacífico (1879-1884). Del mismo modo, reconoce que la génesis del patrimonio y su naturaleza política no pueden entenderse si no a partir de procesos estrechamente ligados a la modernidad.
El contínuum cultural, metodología para una historia integrada
Authors: Espinoza Pajuelo Pedro , Manrique Patricia , Luján Karen , Morales Santiago , Zela Verónica 
Published: September 2023

La metodología del contínuum cultural fue creada en el 2011 durante la intervención arqueológica y de gestión en el complejo arqueológico Mateo Salado (Cercado de Lima). Dicha metodología propone que todas las actividades evidenciadas en un monumento a lo largo del tiempo tienen el mismo valor como modos de vida, conectando así, en la práctica, a la arqueología prehispánica, la arqueología histórica, la arqueología de lo contemporáneo y la arqueología pública. En este marco, cuestiona que el criterio temporal deba ser determinante, ya que privilegia una época en detrimento de las demás y tiende a seleccionar de ese periodo lo que pueda ser difundido grandilocuentemente al público. El contínuum cultural, asimismo, posibilita abordar temas contemporáneos y polémicos desde un monumento usualmente visto solo como prehispánico. Para ilustrar todos estos aspectos, el artículo desarrolla aplicaciones del contínuum cultural en la investigación, la conservación-restauración, y en la gestión hacia la comunidad en Mateo Salado.
A política social no Brasil: notas sobre sua configuração sob a égide neoliberal
Authors: Pinheiro Silvia Silva Martins , Guimarães Karoline Claudino 
Published: September 2023

This article aims to promote an analysis around the format assumed by social policies in Brazil in the face of the intensification of the neoliberal project, with a view to its contradictions and main characteristics. Therefore, a historical review of its foundations is essential, although brief, as well as an approach to the social issue and its deepening in the current scenario. In fact, through a bibliographic review, in the light of Marxist critical social theory, we also sought to discuss social policy in the Brazilian context of Bolsonaro’s government in the face of Covid-19 pandemic, taking as an example the welfare benefit emergency.
DINÂMICAS SOCIOTERRITORIAIS NAS CIDADES AO DESENVOLVIMENTO REGIONAL DO TERRITÓRIO
Authors: Oliveira Adão Francisco de 
Published: September 2023

Este artigo visa apresentar a trajetória formativa desenvolvida por mim no contexto do Programa de Pós-Graduação em Geografia da UFT do campus de Porto Nacional entre 2013 – ano de meu ingresso como professor no programa – e 2023. Não obstante, intenciona realizar uma análise desse itinerário formativo sob a luz das tendências investigativas que se sucederam no interregno e a sua influência sobre as dissertações produzidas pelos orientados. O ponto de partida da análise é a constituição da primeira disciplina ministrada por mim no programa, Dinâmica Socioterritorial nas Cidades: urbanização e metropolização; a sua revisão, que alterou o subtítulo para “urbanização e regionalização”; a instituição de uma segunda perspectiva investigativa a partir da disciplina Desenvolvimento Regional, Cidades e Educação, alterada posteriormente para Educação, Território e Desenvolvimento Regional; e, por fim, à definição da última disciplina, intitulada Dinâmica Territorial do Cerrado e da Amazônia. Ressalta-se que todas estas disciplinas foram embasadas em leituras materialistas históricas da realidade espacial, com foco nas teorias da produção social do espaço e da educação crítica.
Pemafibrate Improves Alanine Aminotransferase Levels Independently of Its Lipid-lowering Effect
Authors: Watanabe Azuma , Horigome Ryoko , Nakatsuka Yumiko , Terai Shuji 
Published: September 2023

AIM
Non-alcoholic　fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Pemafibrate, a selective peroxisome proliferator-activated receptor α modulator (SPPARMα), has been reported to ameliorate liver function among patients with dyslipidemia. However, there are not many reports of the clinical effects of the pemafibrate. This study aims to summarize the experience of using pemafibrate and analyze the effects on liver function in patients with dyslipidemia.
METHODS
One hundred twelve cases of hyperlipidemia receiving pemafibrate 0.2 mg/day were retrospectively enrolled in this study. Age, gender, BMI, complications, concomitant medications, serum parameters (TG, HDL-C, LDL-C, AST, ALT, γGTP, ALP, platelets, M2BPGi, Cre, eGFR, HbA1c, blood glucose level at any time) were investigated and evaluated.
RESULTS
Pemafibrate administration significantly improved serum TG and HDL-C, but not in LDL-C. Serum AST, ALT, γGTP, and ALP were also significantly improved. The fib-4 index, a liver fibrosis score, did not change significantly, but M2-BPGi, an index of fibrosis, decreased significantly. No correlation was observed between each lipid parameter and ALT, and ALT decreased independently of the lipid parameters.
Conclusions
As we expected, pemafibrate demonstrated a lipid-improving effect without adversely affecting hepatic and renal functions. An unexpected finding was the decrease in ALT that was independent of lipid parameters.
Exploring the Enhancement of Rigless Deployed ESP Technology for Ad-Interim Production
Authors: Al-Shunaiber Fahad , Al-Dossari Ibrahim , Windiarto Yhossie 
Published: September 2023

Abstract
The electrical submersible pump (ESP) change-out using the workover rig contributes to significantly deferred production, including waiting for rig availability, wellsite preparation, and rig mobilization. Finding an alternative ESP deployment method to minimize the deferred production associated with ESP failure is always prioritized during peak global oil demand. This paper focuses on the lessons learned from a temporary slim cable deployed ESP field trial installed for the Ad interim production application.
A temporary thru-tubing ESP deployment concept was adopted to allow producing the well until mobilizing the workover rig to replace the failed permanent ESP. The slim cable deployed ESP system uses an inverted high-speed ESP architecture, and the permanent magnet motor offers a broader ESPs operating range and operational flexibility. The compact design simplifies the ESP installation using a standard slickline operation and well-control procedure.
The slim cable deployed ESP system was successfully installed thru 4-1/2-inch tubing above the failed ESP. The system's performance was observed during the field trial period, including fully rigless deployment capability in a live well, ESP operational flexibility, and well control guidelines.
Enhancing Production from High-Enthalpy Geothermal Wells with New Electric Submersible Pump Technology
Authors: Radov M. , Hamitoglu Y. , Sentürk E. , Tüzen M. K. , Holzmueller J. L. , Goertzen W. K. , Nyayadhish V. , Kulkarni O. S. , Amutha Nilavazhagan V. , Wu J. , Tan P. , Rao A. R. , Usta A. T. 
Published: September 2023

Abstract
This paper presents advancements in electrical submersible pump (ESP) technology that were specifically designed for use in high-enthalpy geothermal wells. It discusses the unique challenges associated with geothermal operations and highlights the opportunities offered by the new ESP technology to enhance production from these wells. The paper also provides a comprehensive overview of the key components of the ESP system, including the motor, protector, pump, power cable, motor lead extension, and downhole sensors. The new ESP system demonstrates improved reliability, power density, and operational efficiency by using high-efficiency permanent magnet motors, innovative encapsulation technologies, and optimized pump designs. The paper also highlights the successful field trial of the newly developed geothermal ESP in Kizildere Field that showcased its enhanced reliability and increased production in a high-temperature environment. The findings from this trial have paved the way for the design and implementation of the new ESP system in additional high-enthalpy wells, further expanding the application of ESP technology to geothermal energy extraction. Overall, this paper underscores the transformative potential of ESP technology in enhancing the use of geothermal resources for sustainable energy production.
Ultra-High-Speed High-Gas-Volume-Fraction Pump Development
Authors: Ejim C. E. , Xiao J. , Shakirov A. , Alexeev Y. , Shkolnyi A. 
Published: September 2023

Abstract
Wellbore conditions below bubble point pressure in high gas-oil-ratio (GOR) wells result in very high amount of free gas at the inlet of Electric Submersible Pumps (ESP). Conventional multiphase pumps have limitations handling free gas exceeding 75% intake gas-volume-fraction (GVF). The objective of this work is to develop and field test a new Ultra-High-Speed High-Gas-Volume-Fraction (UHS HGVF) pump system. The ultimate goal is to facilitate sustained production from wells experiencing high-GVF production challenges.
The UHS HGVF pump is a new type of submersible pump with an architecture being investigated to boost hydrocarbon production from high GOR oil wells. The principle of operation is based on turbulent friction, in which a spatial vortex flow is formed, rotating together with the rotor and moving along its axis. The pump housing diameter is 4.00 inches and operates at a shaft rotational speed in excess of 3.5 times those of conventional pump systems. Hydraulic design, computational fluid dynamics analysis, prototyping and physical testing were performed to optimize the performance of the UHS HGVF pump.
The results show that the new pump architecture is capable of handling gas-liquid mixtures with intake GVF well beyond the 75% GVF limitation of conventional multiphase pumps. This was mainly attributed to the pump features, which impart the required amount of energy and turbulence to the gas-liquid mixture but simultaneously minimizes separation of the gas and liquid phases. These combined effects facilitated thorough mixing of the gas-liquid streams ensuring the pump provided sufficient pressure boost for the downhole setting depths which the system was designed. The system was also observed to have a high capability of sand tolerance and thrust handling. The ruggedized system has the required attributes to withstand operation in gassy field conditions.
This work presents a conceptually new approach to pump development with the aim of overcoming hydrocarbon production challenges in wells with very high free gas at pump intake. The UHS HGVF pump widens the operating envelope to produce a high GOR well, thereby achieving production gains in gassy conditions, where conventional systems are limited. The system therefore serves as an essential artificial lift tool to handle production in increasing numbers of extremely gassy wells.