bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving supply chain resilience from the perspective of information processing theory
Authors: Lu Qiang , Jiang Yu , Wang Yu 
Published: April 2023

PurposeSupply chain resilience (SCR) has attracted much attention in the context of the high uncertainty caused by the coronavirus disease 2019 (COVID-19), local regional conflicts and natural disasters. Based on information processing theory (IPT), this study investigates the role of supply chain information processing capability in enhancing SCR through supply chain governance (SCG), under different conditions of environmental uncertainty.Design/methodology/approachThe hypothetical model is tested by using hierarchical regression on the primary samples collected from the Chinese manufacturing industry.FindingsThe results indicate that supply chain information processing capability has a significant positive effect on SCR. Also, SCG plays a mediating role between supply chain information processing capability and SCR. Furthermore, environmental uncertainty positively moderates the effect of supply chain information acquisition and supply chain information analysis on relational governance. However, environmental uncertainty only positively moderates the effect of supply chain information analysis on contractual governance.Originality/valueThis is the first study to explain the effect of information processing capability on SCR from the supply chain perspective, while also exploring the mediating role of SCG between SCR and supply chain information processing capacity, based on IPT.
Exploring drivers of business performance in web-enabled supply chains: the role of web technology training and supply chain integration
Authors: Mora-Monge Carlo A. , Fatoki Jimoh , Arslan Faruk , Rauniar Rupak 
Published: April 2023

PurposeGrounded on the resource-based and dynamic capability views and the contingency theories, this study examines the direct and indirect effects of web technology training (WTT) and web-enabled transaction use (WTU) on business performance (BPE) through internal supply chain integration (ISCI) and supplier supply chain integration (SSCI).Design/methodology/approachBased on survey data collected from a sample of 175 respondents in the USA, the authors used structural equation modeling with AMOS 24.0 to test the measurement model for validity, reliability and the conceptual model for hypothesized structural relationships.FindingsThe results reveal that WTT significantly impacts WTU, which, in turn, has a significant direct relationship with BPE. Further, WTU indirectly affects BPE through SSCI. Additionally, ISCI has a significant direct effect on SSCI.Practical implicationsThe findings support the relationship between WTT and BPE via WTU SCI. Managers are advised to develop ongoing capabilities in WTT to maximize the value of WTU to enhance the ISCI and SSCI operations, thus leading to improvements in BPE.Originality/valueThe research contributes to the supply chain literature by empirically demonstrating the usefulness of WTT in improving WTU use and BPE through effective ISCI and SSCI.
Robotising, but how? Evidence from the automotive sector in South Africa
Authors: Anzolin Guendalina , Andreoni Antonio 
Published: April 2023

PurposeThis paper focuses on understanding firm-level determinants of industrial robots' adoption and how these determinants result in heterogenous processes of robotisation across firms within the same sector. The paper presents results from in-depth case studies of final assemblers in the South African automotive sector.Design/methodology/approachThe research has been conducted through multiple case studies with a focus on final assemblers. During the case studies, as well as before and after it, data coming from in-depth semi-structured interviews were triangulated with secondary data available from the international database on industrial robots' adoption and documents provided by firms and institutions.FindingsThis paper identifies three firm-level determinants of robotisation – i.e. modularity of the production process, flexibility in the use of technology and stability in product design. The results also showed that firms' robotisation depend on each of these determinants as well as their interdependence. The authors introduce a framework to study interdependence between these technology–organisational choices, which reveals heterogenous patterns of technology deployment and related managerial implications.Originality/valueThis research introduces a new framework on factors driving industrial robotisation – a key digital production technology – and offers empirical evidence of the heterogenous deployment of this technology. The authors identify two main manufacturing approaches to robotisation in the automotive sector: one in which the firm designs a robotised process around a certain product design – i.e. the German/American way and one in which the firm designs its product based on certain robotised processes – i.e. the Japanese way. These findings are valuable for both industry, operational research and the scientific community as they reveal heterogeneity on the “how” of robotisation and implications for manufacturing technology management.
Microfoundations of dynamic capabilities: a systematic review and a multilevel framework
Authors: Chen Yantai , Liu Lu , Li Weiwen , Xie Zaiyang , Wei Chenchen 
Published: April 2023

PurposeMicrofoundations have become an effective approach for capability scholars to explore the heterogeneity of organizational results. Since the early pioneering work of scholars such as Felin and Foss, the microfoundations of strategic organization had not been extensively studied until 2010. The theoretical and empirical literature associated with the microfoundations of dynamic capabilities has developed rapidly. However, the diversity and fragmentation of micro-elements lead to a lack of a relatively consistent understanding of microfoundations, the study purpose is to aggregate the associated scattered terminology into a cohesive discussion.Design/methodology/approachA systematic literature review was conducted on research papers published between 2000 and 2022 using a hybrid methodology that included bibliometric and content analysis.FindingsThe authors suggest that this line of research can be divided into three stages. The study further develop a framework delineating the main components and mechanism involved in the microfoundations of dynamic capabilities, which in turn help us distill research gaps and opportunities for future work.Originality/valueThe authors construct a framework that can serve as a coherent research platform for further knowledge development. In the framework, the authors highlight that the research of group constructs, culture and leadership, data-driven topics are valuable for our understanding of the microfoundations of dynamics capabilities.
Bringing the Emigration State Back In
Authors: Foks Freddy 
Published: April 2023

AbstractThe decades between 1948 and 1980 are often remembered as a time of mass immigration, yet almost 2 million more people left Britain than arrived in those years. Mass emigration has been an enduring part of Britain's modern history and this article explores its effects on British politics. The two world wars, the turn to tariffs, joining the EEC and leaving the EU: at these critical junctures, Britain's overseas diaspora was mobilised to reshape domestic politics and to transform the UK's global political economy. Charting the rise, fall and afterlife of Britain's ‘emigration state’ can contribute to our understanding of these events and help researchers analyse the effects of racism and empire on modern British politics.
Interactional power and support in digital inclusion of an adult with intellectual disabilities: a case study analysis
Authors: Chadwick Darren D. , Buell Susan 
Published: April 2023

AbstractDigital inclusion of people with intellectual disabilities is not commensurate with those without disabilities. Societal, political, financial, individual and interpersonal barriers help explain this disparity. Caregivers can act as both support and gatekeeper to internet access and use by adults with intellectual disabilities. This study investigated micro‐level interpersonal factors influencing access and use of the internet by an adult with intellectual disabilities to explore the balance and interplay of power and support around the processes of digital inclusion and online risk taking. Taking a case study approach, perspectives of three key stakeholders were gathered via interviews: the person with intellectual disabilities, his mother and a paid support worker. Perspectives and experiences were contrasted using systemic functional linguistic analysis of discourse to explore the ways power and support were represented in the language of negotiated digital inclusion. Dynamics between the parent and person with intellectual disabilities and between the parent and paid staff clearly influenced processes of digital inclusion and were affected by varying priorities, positions and perceptions of power to allow, disallow and monitor access and use of the internet. These had the power to shape and drive internet access. Language choices by the person with intellectual disabilities showed that he was not fully aware of the risks involved in engaging with certain aspects of digital inclusion but how he spoke about the internet indicated some autonomy in technology use. Supporting the development of digital competence, confidence and resilience in people with learning disabilities should be combined with support to increase self‐awareness regarding digital risk. Those supporting people with intellectual disabilities towards digital inclusion need additional guidance on how to do this effectively for the people they support.
The emerging role of auxins as bacterial signal molecules: Potential biotechnological applications
Authors: Krell Tino , Gavira José A. , Roca Amalia , Matilla Miguel A. 
Published: April 2023

AbstractMicroorganisms are exposed in their natural niches to a wide diversity of signal molecules. Specific detection of these signals results in alterations in microbial metabolism and physiology. Auxins like indole‐3‐acetic acid are key phytohormones that regulate plant growth and development. Nonetheless, auxin biosynthesis is not restricted to plants but is ubiquitous in all kingdoms of life. This wide phylogenetic distribution of auxins production, together with the diversity of regulated cellular processes, have made auxins key intra‐ and inter‐kingdom signal molecules in life modulating, for example microbial physiology, metabolism and virulence. Despite their increasing importance as global signal molecules, the mechanisms by which auxins perform their regulatory functions in microorganisms are largely unknown. In this article, we outline recent research that has advanced our knowledge of the mechanisms of bacterial auxin perception. We also highlight the potential applications of this research in aspects such as antibiotic production, biosensor design, plant microbiome engineering and antivirulence therapies.
Robust rhythm reporting will advance ecological and evolutionary research
Authors: Hersh Taylor A. , Ravignani Andrea , Burchardt Lara S. 
Published: April 2023

Abstract

Rhythmicity in the millisecond to second range is a fundamental building block of communication and coordinated movement. But how widespread are rhythmic capacities across species, and how did they evolve under different environmental pressures? Comparative research is necessary to answer these questions but has been hindered by limited crosstalk and comparability among results from different study species.

Most acoustics studies do not explicitly focus on characterising or quantifying rhythm, but many are just a few scrapes away from contributing to and advancing the field of comparative rhythm research. Here, we present an eight‐level rhythm reporting framework which details actionable steps researchers can take to report rhythm‐relevant metrics. Levels fall into two categories: metric reporting and data sharing. Metric reporting levels include defining rhythm‐relevant metrics, providing point estimates of temporal interval variability, reporting interval distributions, and conducting rhythm analyses. Data sharing levels are: sharing audio recordings, sharing interval durations, sharing sound element start and end times, and sharing audio recordings with sound element start/end times.

Using sounds recorded from a sperm whale as a case study, we demonstrate how each reporting framework level can be implemented on real data. We also highlight existing best practice examples from recent research spanning multiple species. We clearly detail how engagement with our framework can be tailored case‐by‐case based on how much time and effort researchers are willing to contribute. Finally, we illustrate how reporting at any of the suggested levels will help advance comparative rhythm research.

This framework will actively facilitate a comparative approach to acoustic rhythms while also promoting cooperation and data sustainability. By quantifying and reporting rhythm metrics more consistently and broadly, new avenues of inquiry and several long‐standing, big picture research questions become more tractable. These lines of research can inform not only about the behavioural ecology of animals but also about the evolution of rhythm‐relevant phenomena and the behavioural neuroscience of rhythm production and perception. Rhythm is clearly an emergent feature of life; adopting our framework, researchers from different fields and with different study species can help understand why.
Ubiquitin C‐terminal hydrolase L1 after out‐of‐hospital cardiac arrest
Authors: Wihersaari Lauri , Reinikainen Matti , Tiainen Marjaana , Bendel Stepani , Kaukonen Kirsi‐Maija , Vaahersalo Jukka , Romppanen Jarkko , Pettilä Ville , Skrifvars Markus B. ,   The FINNRESUSCI Study Group
Published: April 2023

AbstractBackgroundWe studied the prognostic ability of serum ubiquitin C‐terminal hydrolase L1 (UCH‐L1) after out‐of‐hospital cardiac arrest (OHCA), compared to that of neuron‐specific enolase (NSE).MethodsIn this post‐hoc analysis of the FINNRESUSCI study, we measured serum concentrations of UCH‐L1 in 249 OHCA patients treated in 21 Finnish intensive care units in 2010–2011. We evaluated the ability of UCH‐L1 to predict unfavourable outcome at 12 months (defined as cerebral performance category 3–5) by assessing the area under the receiver operating characteristic curve (AUROC), in comparison with NSE.ResultsThe concentrations of UCH‐L1 were higher in patients with unfavourable outcome than for those with favourable outcome: median concentration 10.8 ng/mL (interquartile range, 7.5–18.5 ng/mL) versus 7.8 ng/mL (5.9–11.8 ng/mL) at 24 h (p < .001), and 16.2 ng/mL (12.2–27.7 ng/mL) versus 11.5 ng/mL (9.0–17.2 ng/mL) (p < .001) at 48 h after OHCA. For UCH‐L1 as a 12‐month outcome predictor, the AUROC was 0.66 (95% confidence interval, 0.60–0.73) at 24 h and 0.66 (0.59–0.74) at 48 h. For NSE, the AUROC was 0.66 (0.59–0.73) at 24 h and 0.72 (0.65–0.80) at 48 h. The prognostic ability of UCH‐L1 was not different from that of NSE at 24 h (p = .82) and at 48 h (p = .23).ConclusionConcentrations of UCH‐L1 in serum were higher in patients with unfavourable outcome than in those with favourable outcome. However, the ability of UCH‐L1 to predict unfavourable outcome after OHCA was only moderate and not superior to that of NSE.
Buildup from birth onward of short telomeres in human hematopoietic cells
Authors: Lai Tsung‐Po , Verhulst Simon , Savage Sharon A. , Gadalla Shahinaz M. , Benetos Athanase , Toupance Simon , Factor‐Litvak Pam , Susser Ezra , Aviv Abraham 
Published: April 2023

AbstractTelomere length (TL) limits somatic cell replication. However, the shortest among the telomeres in each nucleus, not mean TL, is thought to induce replicative senescence. Researchers have relied on Southern blotting (SB), and techniques calibrated by SB, for precise measurements of TL in epidemiological studies. However, SB provides little information on the shortest telomeres among the 92 telomeres in the nucleus of human somatic cells. Therefore, little is known about the accumulation of short telomeres with age, or whether it limits the human lifespan. To fill this knowledge void, we used the Telomere‐Shortest‐Length‐Assay (TeSLA), a method that tallies and measures single telomeres of all chromosomes. We charted the age‐dependent buildup of short telomeres (<3 kb) in human hematopoietic cells from 334 individuals (birth‐89 years) from the general population, and 18 patients with dyskeratosis congenita‐telomere biology disorders (DC/TBDs), whose hematopoietic cells have presumably reached or are close to their replicative limit. For comparison, we also measured TL with SB. We found that in hematopoietic cells, the buildup of short telomeres occurs in parallel with the shortening with age of mean TL. However, the proportion of short telomeres was lower in octogenarians from the general population than in patients with DC/TBDs. At any age, mean TL was longer and the proportion of short telomeres lower in females than in males. We conclude that though converging to the TL‐mediated replicative limit, hematopoietic cell telomeres are unlikely to reach this limit during the lifespan of most contemporary humans.
The One Health approach for allergic diseases and asthma
Authors: Jutel Marek , Mosnaim Giselle S. , Bernstein Jonathan A. , del Giacco Stefano , Khan David A. , Nadeau Kari C. , Pali‐Schöll Isabella , Torres Maria J. , Zemelka‐Wiacek Magdalena , Agache Ioana 
Published: April 2023

AbstractThe One Health approach is a collaborative and interdisciplinary strategy with focal point on human, animal, and environmental health interconnections. One Health can support the advanced management of allergic diseases and asthma, as complex, multifactorial diseases driven by interactions between the resilience response to the exposome. According to the One Health concept allergic diseases and asthma arising from exposures to a wide range of allergens, infectious agents and irritants (such as pollutants) occurring indoors and outdoors can be heavily influenced by environmental health (air, water, and soil quality) intermingled with animal health. These are currently heavily impacted by climate change, land use, urbanization, migration, overpopulation, and many more. Thus, a coordinated response to address the underlying factors that contribute to the development of allergic diseases and asthma needs to focus on the environment, human, and animal health altogether. Collaborative efforts across multiple sectors, including public health, veterinary medicine, environmental science, and community engagement are thus needed. A wide range of activities, including monitoring and surveillance of environmental and health data, targeted interventions to reduce exposures to allergens and irritants, and research on the underlying mechanisms that drive the development of allergic diseases and asthma are needed to move the field forward. In this consensus document elaborated by the European Academy of Allergy and Clinical Immunology (EAACI) and American Academy of Allergy, Asthma, and Immunology (AAAAI) under the practical allergy (PRACTALL) series, we provide insights into the One Heath approach aiming to provide a framework for addressing the complex and multifactorial nature of allergic diseases and asthma.
Ethicizing history. Bioethical representations of Nazi medicine
Authors: Schütz Mathias , Braswell Harold 
Published: April 2023

AbstractThe article presents and analyzes different approaches of U.S. bioethicists in comprehending the Nazi medical crimes after 1945. The account is divided into two sections: one dealing with discussions on research ethics and the Nuremberg Code up until the 1970s and the other ranging from the 1970s to the present and highlighting bioethics' engagement with Nazi analogies. The portrayal of different bioethical scholars, institutions, and documents—most notably Henry K. Beecher, Jay Katz, the Belmont Report, the Hastings Center, Arthur L. Caplan, and Robert M. Veatch—provides a nuanced interpretation of the motives that bioethicists held and the strategies that they applied to establish an understanding of the Nazi medical crimes and their relation to contemporary bioethical issues. In this, the different approaches shared a common goal: To integrate the Nazi medical crimes into an ethical framework by means of selective acknowledgments and representation of their history.
Ethics of live uterus donor compensation
Authors: Lee Ji‐Young 
Published: April 2023

AbstractIn this paper, I claim that live uterus donors ought to be considered for the possibility of compensation. I support my claim on the basis of comparable arguments which have already been applied to gamete donation, surrogacy, and other kinds of organ donation. However, I acknowledge that there are specificities associated with uterus donation, which make the issue of incentive and reward a harder ethical case relative to gamete donation, surrogacy, and other kinds of organ donation. Ultimately, I contend that while reimbursement for the costs incurred by live uterus donors should be treated as a necessary ethical minimum, how much further we ought to remunerate uterus donations remains an open question.
The effects of MYC on exosomes derived from cancer cells in the context of breast cancer
Authors: Celikkaya Busra , Durak Taner , Farooqi Ammad Ahmad , Inci Kubilay , Tokgun Pervin Elvan , Tokgun Onur 
Published: April 2023

AbstractMYC amplification and overexpression in breast cancer occur 16% and 22%, respectively, and MYC has a linchpin role in breast carcinogenesis. Emerging evidence has started to shed light on central role of MYC in breast cancer progression. On the contrary, tumor‐derived exosomes and their cargo molecules are required for the modulation of the tumor environment and to promote carcinogenesis. Still, how MYC regulates tumor‐derived exosomes is still a matter of investigation in the context of breast cancer. Here, we investigated for the first time how MYC affects the biological functions of normal breast cells cocultured with exosomes derived from MYC‐expression manipulated breast cancer cells. Accordingly, exosomes were isolated from MCF‐7 and MDA‐MB‐231 cells that MYC expression was manipulated through siRNAs or lentiviral vectors by using exosome isolation reagent. Then, normal breast epithelial MCF‐10A cells were treated with breast cancer cell‐derived exosomes. The cellular activity of MCF‐10A was investigated by cell growth assay, wound healing assay, and transwell assay. Our results suggested that MCF‐10A cells treated with exosomes derived from MYC‐overexpressing breast cancer cells demonstrated higher proliferation and migration capability compared with nontreated cells. Likewise, MCF‐10A cells treated with exosomes derived from MYC‐silenced cancer cells did not show high proliferation and invasive capacity. Overall, MYC can drive the functions of exosomes secreted from breast cancer cells. This may allow exploring a new mechanism how tumor cells regulate cancer progression and modulate tumor environment. The present study clears the way for further researches as in vivo studies and multi‐omics that clarify exosomal content in an MYC‐dependent manner.