bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting Generalized Anxiety Disorder From Impromptu Speech Transcripts Using Context-Aware Transformer-Based Neural Networks: Model Evaluation Study
Authors: Teferra Bazen Gashaw , Rose Jonathan 
Published: February 2023

Background
The ability to automatically detect anxiety disorders from speech could be useful as a screening tool for an anxiety disorder. Prior studies have shown that individual words in textual transcripts of speech have an association with anxiety severity. Transformer-based neural networks are models that have been recently shown to have powerful predictive capabilities based on the context of more than one input word. Transformers detect linguistic patterns and can be separately trained to make specific predictions based on these patterns.

Objective
This study aimed to determine whether a transformer-based language model can be used to screen for generalized anxiety disorder from impromptu speech transcripts.

Methods
A total of 2000 participants provided an impromptu speech sample in response to a modified version of the Trier Social Stress Test (TSST). They also completed the Generalized Anxiety Disorder 7-item (GAD-7) scale. A transformer-based neural network model (pretrained on large textual corpora) was fine-tuned on the speech transcripts and the GAD-7 to predict whether a participant was above or below a screening threshold of the GAD-7. We reported the area under the receiver operating characteristic curve (AUROC) on the test data and compared the results with a baseline logistic regression model using the Linguistic Inquiry and Word Count (LIWC) features as input. Using the integrated gradient method to determine specific words that strongly affect the predictions, we inferred specific linguistic patterns that influence the predictions.

Results
The baseline LIWC-based logistic regression model had an AUROC value of 0.58. The fine-tuned transformer model achieved an AUROC value of 0.64. Specific words that were often implicated in the predictions were also dependent on the context. For example, the first-person singular pronoun “I” influenced toward an anxious prediction 88% of the time and a nonanxious prediction 12% of the time, depending on the context. Silent pauses in speech, also often implicated in predictions, influenced toward an anxious prediction 20% of the time and a nonanxious prediction 80% of the time.

Conclusions
There is evidence that a transformer-based neural network model has increased predictive power compared with the single word–based LIWC model. We also showed that the use of specific words in a specific context—a linguistic pattern—is part of the reason for the better prediction. This suggests that such transformer-based models could play a useful role in anxiety screening systems.
Ratifikasi Perjanjian Penyesuaian Wilayah Informasi Penerbangan antara Indonesia dan Singapura: Pilihan Rasional atau Status Quo?
Authors: Sutrisno Nandang , Romdoni Rafi Nasrullah Muhammad 
Published: February 2023

The ratification of the Agreement on Realignment of Flight Information Region (FIR) between Indonesia and Singapore by Presidential Regulation Number 109 of 2022 produced controversies. Such controversies occurred between the Indonesian government on one side, and the academicians and practitioners on another. The former claims that the ratification indicates the hard work of the Indonesian government to take over the FIR that has been delegated to Singapore. However, the latter questions the status of Indonesia as a sovereign state and its security that would potentially be arose from the ratification. It is because Singapore still takes control over Indonesia’s airspace from 0-37.000 feets. This article studies and analyzes whether the ratification was the best choice taken by Indonesia. The discussion shows that it was not the best yet rational and realistic. It was not, because the possibility of harm and threat to Indonesia’s national security are bigger than the advantages arising from the agreement. It was rational and realistic because it was not ratified, the control of FIR would be status quo and return fully to Singapore without limitation of time.
Abstrak
Pengesahan Perjanjian Penyesuaian Wilayah Informasi Penerbangan (Flight Information Region/FIR) antara Pemerintah Indonesia dan Pemerintah Singapura melalui Peraturan Presiden Nomor 109 Tahun 2022 menuai polemik. Hal tersebut terjadi antara pihak pemerintah dengan pihak akademisi serta praktisi. Pada satu sisi, pihak pemerintah mengklaim bahwa pengesahan tersebut mengindikasikan kerja keras pemerintah dalam mengambil alih FIR yang didelegasikan kepada Singapura. Oleh karena itu, kini kedaulatan ruang udara dikontrol penuh Indonesia. Namun di sisi lain, para akademisi dan praktisi mempersoalkan status kedaulatan dan juga keamanan yang berpotensi timbul dari pengesahan ini. Hal tersebut dikarenakan Singapura sebenarnya masih memiliki kontrol di ruang udara Indonesia pada ketinggian 0-37.000 kaki. Artikel ini akan mempelajari dan menganalsis apakah pengesahan perjanjian tersebut merupakan langkah yang tepat. Hasil dari kajian artikel ini menunjukkan bahwa pengesahan perjanjian tersebut bukan merupakan langkah terbaik, namun rasional dan realistis. Ia bukan langkah terbaik, disebabkan peluang kerugian dan ancaman terhadap keamanan negara tampak lebih besar dibandingkan keuntungan yang diperoleh dari persetujuan tersebut. Meski demikian, pengesahan ini juga rasional dan realistis, dikarenakan jika tidak disahkan, status FIR akan status quo, tetap sepenuhnya kembali ke Singapura tanpa batas waktu.
Penerapan Ekonomi Sirkular melalui Pembuatan Lilin Aroma Terapi Dari Minyak Bekas
Authors: Emalia Zulfa , Awaluddin Imam , Fajarini Dian , Perdana Ferdi Septiawan 
Published: February 2023

Pengabdian kepada masyarakat ini bertujuan untuk mensosialiasikan konsep ekonomi sirkular dan menerapkannya melalui pembuatan lilin aroma terapi dari minyak goreng bekas. Kegiatan pengabdian kepada masyarakat ini menggunakan metode sosialisasi langsung melalui ceramah, diskusi, dan praktik secara langsung kepada siswa sekolah sasar sebagai sasaran utama. Teknis kegiatan acara sosialisasi yaitu : 1. Survei lokasi. 2. Tim Pelaksana menyiapkan gambaran utama program kerja. 3. Menyiapkan alat penelitian. 4. Evaluasi kegiatan. Kegiatan pengabdian kepada masyarakat ini berjalan lancar dan siswa SDN 10 Tegineneng sangat antusias mengikuti kegiatan. Kegiatan ini juga dapat meningkatakan kreativitas dengan memanfaatkan minyak bekas atau jelantah tersebut menjadi lilin aroma terapi yang bernilai ekonomis dan ramah lingkungan serta memiliki potensi untuk mendukung konsep dari ekonomi sirkular.
Nutrition of Wafer Produced from Silage of Cabbage Vegetable Waste and Rice Brain With Different Packaging Types
Authors: Adelina Triani , Harahap Anwar Efendi , Ali Arsyadi , Harianti Fitri 
Published: February 2023

The wafer packaging process is necessary in maintaining quality during storage and transportation. This study aimed to evaluate the nutritional quality of the wafers produced by silage from various combinations of cabbage vegetable waste and rice bran which were stored using different types of packaging. This research method used factorial design (4x2) with 2 replications. The first (A) factor was the composition of the silage of cabbage and rice bran waste (A0: 100% cabbage waste; A1: 75% cabbage waste + 25% rice bran; A2: 50% cabbage waste + 50% rice bran; A3: 25% cabbage waste + 75% rice bran), while second factor (B)was the type of packaging (B0: plastic packaging; B1: gunny sack packaging). The results showed that the composition of the silage of cabbage and rice bran waste had a very significant effect (P <0.01) Dry matter, crude protein, crude fiber and BETN content of wafers produced. The type of packaging was also had a very significant effect(P <0.01) on dry matter, crude protein, and crude fiber content of the wafer and there was an interaction between materials composition of silage and types of packaging in producing wafer ash. The conclusion of this research is that the substrate composition of 25% cabbage vegetable waste + 75% rice bran and gunny sack packaging could maintain the nutritional quality of the wafers.
The Effect of Altitude on Broiler’s Litter Microbical Quality that Cultivated at Closed House
Authors: Utama Cahya Setya , Sulistiyanto Bambang , Mustofa Alfian 
Published: February 2023

This study aims to assess the quality of microbiology which includes the number of bacteria, mould, gram-positive and gram-negative bacteria found in broiler chicken litter kept in closed-house. The material used is chicken litter taken from 15 farms in Demak (0-100 masl), Semarang (100-300 masl), and Kendal (300-500 masl). This study used a completely randomized design (CRD) with 3 treatments and 5 replications. The results showed that height had a significant effect (P <0.01) on total bacteria and mould in broiler chicken litter. The types of gram-positive bacteria found in the chicken litter are rods (Lactobacillus, and Bacillus), round stems (Clostridium), and coccus (Streptococcus thermophilus). A type of gram-negative bacteria found on rod-shaped stretchers belong to the Coliform and Pseudomonas families. The conclusion of this study is that land elevation has an effect on the microbiological quality of broiler chickens kept in closed cages.
The Effects of New Service Development Antecedents On New Service Performance: A Research On E-Commerce Businesses
Authors: SÖNMEZAY Mine 
Published: February 2023

Purpose: The purpose of this dissertation is to determine the dimensions of e-commerce businesses in service innovation and to reveal the effects of these dimensions on new service performance, along with the effects of new service accomplishment on the marketing performance of e-commerce businesses.
Method: The research was conducted between June 18, 2020 - September 20, 2020. The convenience sampling method was used in the study. The data collected from the research conducted on e-commerce companies were analyzed by Structural Equation Modeling (SEM).
Findings: According to the results of the analysis, it has been found that the exogenous variables of strategic investment, service innovation experience, information technology experience, and competitive environment have a significant and positive impact on the new service performance of e-commerce businesses. However, exogenous variables of risk tolerance, collaboration, and consumer demand did not substantially affect the service innovation performance of e-commerce businesses. In addition, as a result of the analysis, service innovation performance on marketing performance has also been found to have a significant and positive impact.
Discussion: It can be stated that it is essential for e-commerce businesses to gain experience in service innovations, to analyze the competitive environment correctly, and focus on information technologies and their strategic investments in service innovations.
D-dimer PERBEDAAN PENINGKATAN KADAR D-DIMER PADA DEWASA DAN LANSIA YANG TERKONFIRMASI COVID-19 DI RS SWASTA BINTARO
Authors: Amelia  
Published: February 2023

Coronavirus Disease 2019 (COVID-19) merupakan penyakit yang disebabkan oleh virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Manifestasi klinis yang disebabkan oleh infeksi SARS-CoV-2 beragam dimulai dari gejala asimtomatik sampai simtomatik yang dapat menyebab kematian. Salah satu manifestasi klinis yang ditimbulkan yaitu peningkatan parameter koagulasi seperti D-Dimer. Tujuan penelitian mengetahui perbedaan peningkatan kadar D-Dimer pada pasien dewasa dan lansia yang terkonfirmasi COVID-19 di salah satu rumah sakit swasta daerah Bintaro. Jenis penelitian yaitu penelitian sekunder dengan desain cross sectional. Metode pengambilan data yang digunakan yaitu purposive sampling dan metode analisis uji Mann-Whitney. Waktu penelitian dilakukan pada 15 Maret 2021 dengan periode data yang diambil sejak September 2020 hingga Februari 2021. Kriteria inklusi yaitu pasien menderita COVID-19 terkonfirmasi PCR, dewasa (rentang usia 26 – 45 tahun), dan lansia (rentang usia 46 – 65 tahun), memiliki kadar D-Dimer >500 ng/ml dan tidak terapi antikoagulan. Kriteria eksklusi yaitu pasien dalam kondisi hamil. Hasil pengambilan data diperoleh sebanyak 86 sampel yang terdiri dari kelompok dewasa sebanyak 46 sampel dan kelompok lansia sebanyak 40 sampel. Data hasil pemeriksaan kadar D-Dimer sebanyak 86 sampel dengan rata-rata kenaikan kadar D-Dimer pada kelompok dewasa yaitu 1151.53 ng/ml dan kelompok lansia yaitu 1416.86 mg/ml. Hasil uji normalitas menunjukkan data tidak berdistribusi normal maka dilanjutkan uji komparatif Mann-Whitney. Hasil uji Mann Whitney didapatkan nilai p= 0.795, berarti pada α= 0.05 terlihat tidak ada perbedaan yang signifikan peningkatan D-Dimer pada kelompok dewasa dan lansia yang terkonfirmasi COVID-19. Peningkatan kadar D-Dimer pada infeksi COVID-19 tidak dipengaruhi usia melainkan respon inflamasi sistemik yang menyebabkan gangguan koagulasi.
Kata kunci : D-Dimer , Dewasa, Lansia, COVID-19, dan Koagulasi.
A novel rat model for longitudinal electrophysiological evaluation after cold-induced brain injury
Authors: Maeda Yuyo , Mitsuhara Takafumi , Takeda Masaaki , Kawate Ayano , Kawano Reo , Shimizu Kiyoharu , Kuwabara Masashi , Hosogai Masahiro , Yuge Louis , Horie Nobutaka 
Published: February 2023

OBJECTIVE
Cerebral contusion models of cold-induced injury are widely used in animal studies. However, owing to the difficulty of longitudinal recording of electrical stimulation transcranial motor evoked potential (tcMEP) in brain injury models of incomplete paralysis, to the authors’ knowledge there have been no multimodal evaluations of cold-induced brain injury models that have included motor function and electrophysiological and histological evaluations. Therefore, in this study the authors aimed to perform a multimodal evaluation of a rat model of brain injury.

METHODS
A brain injury model in female rats and a tcMEP recording technique based on the authors’ previous study were established to enable multifaceted analysis, including longitudinal electrophysiological evaluation.

RESULTS
The model showed incomplete paralysis of the right forelimb. Motor function showed recovery over time, and histological evaluation showed tissue changes associated with cerebral contusion. In addition, stable tcMEP waveforms were recorded before and after surgery and up to 4 weeks after injury. The tcMEP amplitude decreased significantly after injury and recovered over time. Furthermore, the amplitudes at 1, 7, and 14 days after injury were significantly lower than those at preinjury (p < 0.0006, p < 0.0007, and p < 0.0067, respectively).

CONCLUSIONS
In the present study, the authors established a novel cold-induced brain injury rat model and technique that allowed for the evaluation of longitudinal tcMEP recording and demonstrated that multimodal evaluation for brain injury can be performed. This model can potentially be applied in future investigations of various therapies for brain injury.
Single-session stereotactic radiosurgery for large perioptic meningiomas
Authors: El-Shehaby Amr M. N. , Reda Wael A. , Abdel Karim Khaled M. , Nabeel Ahmed M. , Emad Eldin Reem M. , Tawadros Sameh R. 
Published: February 2023

OBJECTIVE
Meningiomas close to the optic pathway are commonly candidates for microsurgical decompression, more so if they are large perioptic meningiomas. However, microsurgery itself imposes risk to vision, and the larger the tumor, the more the risk and the lower the possibility of postoperative visual recovery. Fractionated stereotactic radiotherapy is usually reserved for such cases. The purpose of this study was to assess the long-term efficacy and safety of single-session stereotactic radiosurgery (SRS) for large (≥ 10 cm3) perioptic intracranial benign meningiomas.

METHODS
This retrospective study included 175 patients with large perioptic benign meningiomas (≥ 10 cm3) who were treated by single-session SRS. Perioptic meningiomas were defined as meningiomas touching, compressing, or within 3 mm of the optic pathway. The median tumor volume was 15 cm3 (range 10–57.3 cm3, IQR 8.4 cm3). The median prescription dose was 12 Gy (range 9–14 Gy, IQR 1 Gy).

RESULTS
The median follow-up period was 72 months (range 13–217 months, IQR 65 months). The tumor control rate was 92%. The progression-free survival rates at 5 and 10 years were 97% and 80%, respectively. Favorable (better/stable) visual outcome was reported in 169 patients (97%) and unfavorable (worse) outcome in 6 patients (3%). Temporary adverse radiation effects were observed in 21 patients (12%), but only 7 patients (4%) were symptomatic. Sixty-three patients had a blind/nonuseful eye according to the pretreatment visual field examination. Visual improvement was observed in the blind/nonuseful eye in 17 patients (27%), while vision remained unchanged in 46 patients (73%). Ocular nerve palsy improved in 36 patients (61%). Tumor shrinkage was not a prerequisite for cranial nerve improvement.

CONCLUSIONS
SRS provides an effective and safe treatment option for large perioptic meningiomas.
Cerebellar deep brain stimulation for the treatment of movement disorders in cerebral palsy
Authors: Cajigas Iahn , Morrison Melanie A. , Luciano Marta San , Starr Philip A. 
Published: February 2023

OBJECTIVE
Cerebral palsy (CP) represents the most common childhood physical disability that encompasses disorders of movement and posture attributed to nonprogressive disturbances that occurred in the developmental fetal or infant brain. Dyskinetic CP (DCP), the second most common type of CP after spastic forms, refers to a subset of patients in whom dystonia and choreoathetosis are the predominant motor manifestations. Most children with CP have abnormal brain MRI studies indicative of cortical and deep gray matter damage consistent with hypoxic ischemic encephalopathy, which may preclude or suggest decreased efficacy of standard deep brain stimulation (DBS) targets. The cerebellum has been posited as an attractive target for treatment of DCP because it is frequently spared from hypoxic ischemic damage and has shown promise in alleviating patient symptoms both in early work in the 1970s and in more recent case series with DBS.

METHODS
The authors performed bilateral cerebellar DBS implantation, targeting the dentate nucleus (DN) and cerebellar outflow pathway, in 3 patients with DCP. Leads were connected to a pulse generator that senses local field potentials during chronic continuous DBS. The authors report their surgical methods, examples of chronic cerebellar local field potential recordings, and preliminary clinical outcomes. Motor outcomes were assessed using the Burke-Fahn-Marsden Dystonia Rating Scale.

RESULTS
Three patients 14–22 years old with DCP and MRI evidence of structural damage to the basal ganglia were offered cerebellar stimulation targeting the DN. All patients tolerated the procedure well and demonstrated improvement in subjective motor function as well as objective improvement in the Burke-Fahn-Marsden Dystonia Rating Scale movement subscale, although the range of responses was variable (19%–40%). Patients experienced subjective improvement in motor function including ease of hand movements and coordination, gait, head control, speech, decreased overflow, and diminished muscle tightness.

CONCLUSIONS
DBS of the dentate nuclei in patients with DCP appears to be safe and shows preliminary evidence of clinical benefit. New chronic sensing technology may allow for determination of in vivo mechanisms of network disruption in DCP and allow for further understanding of the effects of neuromodulation on brain physiology. Larger studies with long-term follow up will be required to further elucidate the clinical benefits of this therapy. This report addresses a gap in the literature regarding the technical approach to image-based stereotactic targeting and chronic neural recording in the DN.
Introduction to Islamic Characters through Children's Karawitan at KB Among Putro Jangkang Sleman
Authors: Muarofakh Muarofakh 
Published: February 2023

Indonesia's diverse culture is unique to each region, especially Javanese culture. Javanese society that is thick in its character becomes an ancestral heritage that must be preserved. The large number of young people who are not interested in Javanese culture, it is very important to preserve it starting with introducing karawitan in early childhood. This research uses a qualitative descriptive approach with the research subjects of KB Among Putro Jangkang Sleman students aged 3-6 years.
The results of the study showed that karawitan can introduce Islamic characters to children by collaborating with various school stakeholders such as heads, teachers and parents of guardians of students. The character is introduced through a dolanan song and sung along with a gamelan instrument. The child easily understands the song and the meaning contained in the song..
Terapias dirigidas a Janus quinasa en las diferentes enfermedades reumatológicas autoinmunes un enfoque basado en mecanismos
Authors: Pucha Aguinsaca Karina Fernanda , Cedillo Prado Jennifer Giomara , Jimenez Jara Jayleen Stefanny , Mora Flores Jeimi Adriana , Ramirez Nieto Xavier Ernesto , Zamora Montealegre Fernanda Alejandra 
Published: February 2023

Introducción: La terapia dirigida a Janus quinasa (JAK) se ha convertido en un enfoque prometedor en el tratamiento de algunas patologias reumatológicas autoinmunes, incluyendo la A.R, espondilitis anquilosante, artritis psoriásica, etc. Objetivo: Evaluar el papel de las terapias que emplean Janus quinasa en el tratamiento de enfermedades reumatológicas autoinmunes y comprender el mecanismo de acción de estas terapias. Metodología: Se empleo una recopilación de información en revistas científicas, utilizando herramientas de investigación de bibliotecas, bases de datos y motores de búsqueda. Resultados: Las terapias dirigidas a la Janus quinasasa han demostrado seguras y efectivas en el tratamiento de la artritis reumatoide, la espondilitis anquilosante, lupus eritematoso sistémico y la vasculitis. Se recomienda monitorear a los pacientes durante el tratamiento. Conclusión: Los estudios clínicos han demostrado que estos medicamentos son seguros y efectivos en estas enfermedades demostrando también resultados prometedores en otras enfermedades autoinmunes. Sin embargo, es esencial continuar investigando para determinar la eficacia y seguridad a largo plazo. Área de estudio: medicina