bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Pengetahuan Dengan Kepatuhan Siswa SMA Angkasa Kabupaten Maros Dalam Menerapkan Protokol Kesehatan Pada Masa Pandemi
Authors: Ikhsan Andi Muhammad Nur , Yusriani  , Nurgahayu  
Published: July 2023

Covid-19 masih menjadi ancaman bagi seluruh masyarakat meskipun sekarang kondisi telah membaik akan tetapi masyarakat masih kurang menyadari akan sikap yang harus dilakukan, meskipun sekarang keadaan sudah membaik mestinya masyarakat selalu memperhatikan untuk mematuhi protokol kesehatan 5M, karena sebelum covid-19 muncul masyarakat sudah menggunakan masker. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dengan kepatuhan 5M di SMA ANGKASA Kabupaten Maros dalam menerapkan protokol kesehatan dimasa pandemi tahun 2022. Jenis penelitian ini menggunakan kuantitatif dengan rancangan cross sectional study. Populasi pada penelitian ini yaitu sebanyak 232 siswa. Teknik pengambilan sampel dengan menggunakan random sampling dengan jumlah 100 responden. Data diperoleh dengan menggunakan kuesioner. Data dianalisis dengan uji chi-square pada tingkat kepercayaan 95% (alpha=0.05). Dari hasil penelitian diperoleh bahwa tidak ada hubungan antara pengetahuan dengan kepatuhan 5M bahwa nilai p value =0.121<0.05 di SMA ANGKASA Kabupaten Maros Tahun 2022. Peneliti menyarankan agar sekolah tetap memepertahankan protokol kesehatan dalam menggunakan masker dengan baik dan benar yaitu dengan menutupi hidung dan mulut ketika berbicara dengan orang lain.
Identifikasi Bahaya Baktriologi Pada Makanan Dengan Prinsip HAACCP Di Rumah Makan Padang Kota Makassar
Authors: Latampung Nursyachdewi , Muhammad Ikhtiar  , Rahman  
Published: July 2023

Hazard Analysis Critical Control Point adalah suatu system control dalam upaya pencegahan terjadinya masalah keamanan pangan yang didasarkan atas identifikasi bahaya di dalam tahap penanganan pangan dan proses produksi. Tujuan penelitian ini adalah untuk mengetahui bagaimana identifikasi bahaya bakteriologi pada bahan makanan dengan prinsip Hazard Analisis Critical Control Point (HACCP) di rumah makan Padang Kota Makassar. Jenis penelitian yang digunakan adalah penelitian deskriptif observasional dengan pengujian laboratorium Sampel dalam penelitian ini adalah bahan makanan yaitu daging, sayur yang ada di 5 rumah makan padang di beberapa Kecamatan Kota Makassar. metode analisis data dengan menggunakan analisis univariat. Hasil penelitian ini menunjukan bahwa di lokasi penelitian yaitu 5 rumah makan padang terdapat kandungan bakteri seperti escherhichia coli pada bahan makanan berdasarkan uji laboratorium. Kemudian dari hasil identifikasi bahaya, sumber bahaya biologi yaitu berasal dari personal hygiene penjamah makanan serta sanitasi rumah makan yang kurang baik. Titik kritis ditemukan dalam beberapa tahapan proses pengolahan pangan. Serta dilakukan tindakan perbaikan pada setiap bahaya pada makanan maupun tahapan proses. Penjamah diharapkan dapat mengingat pentingnya penjamah makanan untuk menjaga kebersihan diri dan sanitasi rumah makan agar makanan tidak mudah terkontaminasi oleh bakteri.
Faktor Yang Berhubungan Dengan Tindakan Tidak Aman Pekerja Operator Bongkar Muat Di PT. Pelindo
Authors: Jihan Nabila  , Andi Sani  , Ella Andayanie  
Published: July 2023

Tindakan tidak aman (unsafe action) adalah perilaku atau tindakan manusia yang dapat memungkinkan terjadinya kecelakaan pada diri sendiri maupun orang lain pada saat bekerja, tindakan tidak aman dapat meningkatkan kemungkinan bahaya atau cedera hingga kematian bagi pekerja. Adapun data kecelakaan kerja yang di dapatkan dari PT Pelindo IV (Persero) Makassar New Port dalam pekerja bagian operator bongkar muat pada tahun 2021 bahwa terdapat 7 kasus kecelakaan kerja yang telah terjadi. Hal ini disebabkan oleh pekerja yang tidak berperilaku K3 atau disebabkan karena tindakan serta kondisi lingkungan yang tidak aman. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan tindakan tidak aman (unsafe action ) pada pekerja bagian operator bongkar muat. Jenis penelitian ini merupakan penelitian kuantitatif dengan desain cross sectional study dan pengambilan sampel total sampling. Populasi dalam penelitian ini adalah seluruh operator PT Pelindo IV (Persero) Makassar New Port, yaitu sebanyak 48 operator. Analisis data menggunakan uji bivariat dengan uji kolerasi Chi-square pada tingkat kepercayaan 95% (p=0,05). Hasil penelitian ini menunjukkan bahwa ada hubungan antara masa kerja dengan tindakan tidak aman (p value = 0,001), ada hubungan antara pengetahuan dengan tindakan tidak aman (p value = 0,018), ada hubungan antara kelelahan kerja dengan tindakan tidak aman (p value = 0,000), tidak ada hubungan antara pengawasan K3 dengan tindakan tidak aman (p value = 0,662), tidak ada hubungan antara penggunaan APD dengan tindakan tidak aman ( p value 0,739). Saran peneliti kepada perusahaan untuk mengoptimalkan penerapan keselamatan dan kesehatan kerja melalui pelatihan, meningkatkan pengawasan di lapangan.
Dukungan Teman Sebaya Berhubungan Dengan Konsumsi Tablet Tambah Darah Pada Remaja Putri
Authors: Ilham A. Fasya Tenri Awaru , Yusriani Yusriani , Bur Nurdardiansyah 
Published: July 2023

Sekitar 40% di Negara berkembang berkaitan dengan anemia pada masyarakat dan kebanyakan anemia pada masyarakat khususnya remaja putri yang terjadi disebabkan oleh defisiensi besi. Defisiensi besi dapat dicegah dengan mengkonsumsi suplemen tablet tambah darah diberikan untuk menghindari remaja putri dari anemia. Pemberian Tablet Tambah Darah (TTD) merupakan cara efektif untuk mengatasi masalah anemia, apabila dikonsumsi secara rutin akan terjadi peningkatan pada kadar Hb. Penelitan ini bertujuan untuk mengetahui hubungan dukungan teman sebaya dengan konsumsi tablet tambah darah pada remaja putri di SMP Negeri 1 Mamuju. Jenis penelitian ini menggunakan metode kuantitatif dan rancangan cross-sectional study dengan jumlah sampel 72 responden. Pengolahan data pada penelitian ini menggunakan metode komputerisasi dengan bantuan Software SPSS untuk menghasilkan informasi yang jelas dan benar sesuai dengan tujuan penelitian. Metode analisis data menggunakan Univariat, Bivariat dengan uji Chi-square pada tingkat kepercayaan 95% (α=0,05). Hasil penelitian diperoleh bahwa variabel yang berhubungan terhadap konsumsi Tablet Tambah Darah (TTD) pada remaja putri adalah dukungan teman sebaya. Diharapkan kepada remaja putri untuk meningkatkan konsumsi tablet tambah darah dimasa remaja dan sedini mungkin agar dapat terhindar dari penyakit anemia dan bisa menjadikan remaja putri generasi yang sehat dan cerdas dimasa mendatang.
Morfologi Insang Ikan Lele Mutiara (Clarias gariepinus Burchell, 1822) yang Diberi Paparan Mikroplastik Polietilen (PE) pada Pakan
Authors: Suwartiningsih Nurul , Sunggoro Glady , Dhiaulhaq Raffly Muhammad , Sari Lyly Nur Indah , Maharani Kurnia Suci , Putra Ichsan Luqmana Indra , Setiawan Haris 
Published: July 2023

Microplastics in the body of fish can damage the function of organs. One of the aquatic biota that can be affected by microplastics is Mutiara catfish. The study aimed to compare the gill morphology of Mutiara catfish after being exposed to microplastics. This study was an experimental study consisting of four treatments, feed treatment with microplastic added with a weight of 0.00 mg/0.75 g feed (control); 0.01 mg/ 0.75 g feed (P1); 0.1 mg/0.75 g (P2); and 1 mg/0.75 g (P3). Each treatment was repeated seven times (seven buckets) and each bucket was filled with five fish so that a total of 140 fish were used. The treatment was carried out for 28 days. Observation of growth parameters was carried out on the entire population, 140 fish, while organ preparation was carried out on a sample of three fish from each treatment. Fish samples were taken using a stratified random sampling technique. Research parameters include gill weight, primary lamela length (LP) and secondary lamela lenght (LS). The results showed the highest gill weight at control 1.76 ± 0.47 g and the lowest at P1 1.20 ± 0.25 g, although it did not significantly different. The highest gill weight/ body weight at control 0.06 ± 0.02 g and the lowest P1 and P2 0.04 ± 0.00 g, although it did not significantly different. Primary lamela length (LP) was highest at P3 1250.34 ± 294.81 μm and lowest at Control 894.78 ± 399.10 μm, and it was significantly different. Secondary lamela lenght (LS) was highest at P3 33.69 ± 4.34 μm and lowest at P1 29.12 ± 5.29 μm. Among controls, P2 and P3; LS length did not significantly different. Microplastic PE up to 1.00 mg/ 0.75 g of feed does not result in a decrease of gill weight and elongation of secondary lamela, but results in significant lengthening of primary lamela.
MENINGKATKAN KINERJA PEMASARAN MELALUI CUSTOMER INVOLVEMENT: PENGEMBANGAN SERVICE DOMINANT LOGIC
Authors: Ali Ali 
Published: July 2023

Tujuan penelitian ini untuk pengembangan konsep Service Dominant Logic (SDL) untuk mengatasi kesenjangan hasil penelitian pengaruh inovasi pemasaran dan kapabilitas pemasaran terhadap kinerja pemasaran. Populasi penelitan ini yaitu industri mebel ekspor di Kabupaten Jepara sejumlah 307. Penentuan jumlah sampel dengan rumus Slovin
didapat sebanyak 171. Teknik pemilihan sampel dengan teknik probability sampling dan dipilih simple random sampling. Hasil pengujian hipotesis menunjukkan inovasi pemasaran, kapabilitas pemasaran dan customer involvement berpengaruh signifikan terhadap kinerja pemasaran. Secara implikasi teoritis berdampak pada pengembangan teori Service Dominant Logic bahwa inovasi pemasaran dan kapabilitas pemasaran dan customer involvement berpengaruh terhadap kinerja pemasaran. Implikasi manajerial, industri mebel harus mempunyai kreasi produk dengan variasi desain, melakukan kreasi produk, dan produk-produk baru. Customer involvement mempunyai kontribusi dalam meningkatkan kinerja pemasaran. Keterbatasan penelitian, belum memiliki variabel-variabel baru yang berhubungan dengan perkembangan era digital marketing yang mempengaruhi kinerja pemasaran, belum bisa menjangkau respon seluruh industri mebel di Kabupaten Jepara dan luar Jepara.
PERAN MARKETING MIX PADA UPAYA MENINGKATKAN PENJUALAN DI PT MEDEQ MANDIRI UTAMA
Authors: Lestari Dyah Ayu , Nurwahyudi Muhammad Robi 
Published: July 2023

Abstract

The marketing mix is a modification of the traditional marketing concept which originally only consisted of 4 factors. There is an increasing need for marketing concepts so that the marketing mix develops into 7 factors. Using a type of qualitative research that is descriptive. with the method used to research on natural object conditions, where the researcher is the key instrument, data collection techniques are carried out by triangulation including a combination of observation, interviews and documentation. This research is to determine the role of marketing mix in efforts to increase sales at PT Medeq Mandiri Utama. So the object of this study is the role of the marketing mix in efforts to increase sales. The implemented marketing mix strategy plays a very important role in increasing sales volume, one of which is increasing the number of customers and bringing in profits. Besides that, it can improve product quality, competitive prices and sales promotions.

Keyword: marketing mix, marketing, sales effort

Abstrak

Marketing mix adalah modifikasi dari konsep pemasaran tradisonal yang awalnya hanya terdiri dari 4 faktor. Adanya kebutuhan konsep pemasaran yang semakin meningkat sehingga marketing mix berkembang menjadi 7 faktor. Menggunakan jenis penelitian kualitatif yang bersifat deskriptif. dengan metode yang digunakan untuk meneliti pada kondisi obyek yang alamiah, dimana peneliti merupakan instrument kunci, teknik pengumpulan data dilakukan secara triangulasi meliputi gabungan observasi, wawancara dan dokumentasi Penelitian ini untuk mengetahui peran marketing mix pada upaya meningkatkan penjualan di PT Medeq Mandiri Utama. Maka objek dalam penelitian ini adalah peran marketing mix pada upaya meningkatkan penjualan. Strategi marketing mix yang diimplementasikan berperan sangat penting dalam peningkatan volume penjualan, salah satunya adalah peningkatan jumlah pelanggan dan mendatangkan keuntungan. Selain itu dapat melakukan peningkatan produk yang berkualitas, harga yang bersaing dan promosi penjualan.
Keyword: bauran pemasaran, pemasaran, upaya penjualan
DAMPAK KEBIJAKAN KREDIT, RESIKO ASET, DAN LEVERAGE TERHADAP KINERJA BANK
Authors: Indriastuti Ariyani , Susetyarsi Theresia 
Published: July 2023

The occurrence of the Covid-19 pandemic affected various sectors including banking due to the declining performance and ability to pay credit in the production sector to banks. The purpose of this study was to analyze the effect of the variable lending as measured by LDR, the effect of bank asset risk as measured by RWA, and bank leverage on bank performance. This study was conducted at 23 Commercial Banks in Indonesia, the results found that LDR and RWA had a significant positive effect on profitability. Leverage has a negative and insignificant effect on profitability

Keywords: LDR, RWA, leverage, profitability
Ultrafast laser volume nanostructuring; a limitless perspective
Authors: Stoian Razvan 
Published: July 2023

Ultrafast lasers are now unanimously recognized as processing tools capable of providing utmost precision. This becomes key in the context of material processing as precise feature scales can render a range of new characteristics to the processed materials. These features redesign their properties optically, mechanically, electrically, or from a chemical point of view. Precision is often accompanied by an increase in resolution. The advances in optical beam engineering and irradiation strategies, alongside with controlled material responses, have put in sight the opportunity to reach record small feature sizes, below 100 nm. Is there an intrinsic limit to optical fabrication? What are the new opportunities provided by laser processing on these scales? How one can make light adapt to matter and at the same time control the matter’s response under light on the smallest scales? In this article I intend to provide a brief overview into the latest developments in ultrafast laser volume nanostructuring, fundamentals and applications alike, stressing out the prospective roadmap and the new potential emerging from super-resolved ultrafast smart laser processing technologies.
Electrospun core–sheath PCL nanofibers loaded with nHA and simvastatin and their potential bone regeneration applications
Authors: Qian Chenghui , Liu Yubo , Chen Si , Zhang Chenyang , Chen Xiaohong , Liu Yuehua , Liu Ping 
Published: July 2023

Introduction: Drugs and biocompatible nanoparticles have raised significant potential in advancing the bone regeneration. Electrospinning technology enables the full realization of the value of drugs and nanoparticles.Methods: In this study, we have successfully fabricated core–sheath nanofibers solely composed of polycaprolactone (PCL) polymer. Simvastatin (SIM) was confined to the core of the nanofibers while nanohydroxyapatite (nHA) was loaded on the nanofiber surface.Results: All the prepared nanofibers exhibited a cylindrical micromorphology, and the core–sheath structure was exploited using a Transmission Electron Microscope. X-ray pattern results indicated that SIM was in an amorphous state within nanofibers, while Fourier Transform InfraRed spectroscopy showed excellent chemical compatibility among SIM, nHA, and PCL. The actual loading of nHA within the nanofiber was determined by a thermogravimetric test due to the high melting point of nHA. Core–sheath nanofibers could release SIM for 672 h, which was attributed to the core–sheath structure. Furthermore, nanofibers loaded with SIM or nHA had a positive impact on cell proliferation, with the core–sheath nanofibers displaying the most favorable cell proliferation behavior.Discussion: Such a synergistic facilitation strategy based on materials and nanostructure may encourage researchers to exploit new biomedical materials in future.
Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors
Authors: Neuman Samuel S. , Metzger Jeanette M. , Bondarenko Viktoriya , Wang Yuyuan , Felton Jesi , Levine Jon E. , Saha Krishanu , Gong Shaoqin , Emborg Marina E. 
Published: July 2023

Introduction: Targeted gene editing is proposed as a therapeutic approach for numerous disorders, including neurological diseases. As the brain is organized into neural networks, it is critical to understand how anatomically connected structures are affected by genome editing. For example, neurons in the substantia nigra pars compacta (SNpc) project to the striatum, and the striatum contains neurons that project to the substantia nigra pars reticulata (SNpr).Methods: Here, we report the effect of injecting genome editors into the striatum of Ai14 reporter mice, which have a LoxP-flanked stop cassette that prevents expression of the red fluorescent protein tdTomato. Two weeks following intracerebral delivery of either synthetic nanocapsules (NCs) containing CRISPR ribonucleoprotein targeting the tdTomato stop cassette or adeno-associated virus (AAV) vectors expressing Cre recombinase, the brains were collected, and the presence of tdTomato was assessed in both the striatum and SN.Results: TdTomato expression was observed at the injection site in both the NC- and AAV-treated groups and typically colocalized with the neuronal marker NeuN. In the SN, tdTomato-positive fibers were present in the pars reticulata, and SNpr area expressing tdTomato correlated with the size of the striatal genome edited area.Conclusion: These results demonstrate in vivo anterograde axonal transport of reporter gene protein products to the SNpr following neuronal genome editing in the striatum.
The application and progress of stem cells in auricular cartilage regeneration: a systematic review
Authors: Liu Yu , Wu Wenqing , Seunggi Chun , Li Zhengyong , Huang Yeqian , Zhou Kai , Wang Baoyun , Chen Zhixing , Zhang Zhenyu 
Published: July 2023

Background: The treatment of microtia or acquired ear deformities by surgery is a significant challenge for plastic and ENT surgeons; one of the most difficult points is constructing the scaffold for auricular reconstruction. As a type of cell with multiple differentiation potentials, stem cells play an essential role in the construction of cartilage scaffolds, and therefore have received widespread attention in ear reconstructive research.Methods: A literature search was conducted for peer-reviewed articles between 2005 and 2023 with the following keywords: stem cells; auricular cartilage; ear cartilage; conchal cartilage; auricular reconstruction, regeneration, and reparation of chondrocytes; tissue engineering in the following databases: PubMed, MEDLINE, Cochrane, and Ovid.Results: Thirty-three research articles were finally selected and their main characteristics were summarized. Adipose-derived stem cells (ADSCs), bone marrow mesenchymal stem cells (BMMSCs), perichondrial stem/progenitor cells (PPCs), and cartilage stem/progenitor cells (CSPCs) were mainly used in chondrocyte regeneration. Injecting the stem cells into the cartilage niche directly, co-culturing the stem cells with the auricular cartilage cells, and inducing the cells in the chondrogenic medium in vitro were the main methods that have been demonstrated in the studies. The chondrogenic ability of these cells was observed in vitro, and they also maintained good elasticity and morphology after implantation in vivo for a period of time.Conclusion: ADSC, BMMSC, PPC, and CSPC were the main stem cells that have been researched in craniofacial cartilage reconstruction, the regenerative cartilage performed highly similar to normal cartilage, and the test of AGA and type II collagen content also proved the cartilage property of the neo-cartilage. However, stem cell reconstruction of the auricle is still in the initial stage of animal experiments, transplantation with such scaffolds in large animals is still lacking, and there is still a long way to go.
Effect and possible mechanisms of saponins in Chinese herbal medicine exerts for the treatment of myocardial ischemia-reperfusion injury in experimental animal: a systematic review and meta-analysis
Authors: Sun Jiahao , Fan Jiarong , Yang Fan , Su Xin , Li Xinye , Tian Li , Liu Can , Xing Yanwei 
Published: July 2023

IntroductionPreventing ischemia-reperfusion injury is the main direction of myocardial infarction treatment in the convalescent stage. Some studies have suggested that saponins in Traditional Chinese medicine (TCM) preparations can protect the myocardium by various mechanisms. Our meta-analysis aims to evaluate the efficacy of TCM saponins in treating myocardial ischemia-reperfusion injury (MIRI) and to summarize the potential molecular mechanisms further.MethodsWe conducted a literature search in six electronic databases [Web of Science, PubMed, Embase, Cochrane Library, Sinomed, China National Knowledge Infrastructure (CNKI)] until October 2022.ResultsSeventeen eligible studies included 386 animals (254 received saponins and 132 received vehicles). The random effect model is used to calculate the combined effect. The effect size is expressed as the weighted average difference (WMD) and 95% confidence interval (CI). Compared with placebo, saponins preconditioning reduced infarct size after MIRI significantly (WMD: −3.60,95% CI: −4.45 to −2.74, P &lt; 0.01, I2: 84.7%, P &lt; 0.001), and significantly increased EF (WMD: 3.119, 95% CI: 2.165 to 4.082, P &lt; 0.01, I2: 82.9%, P &lt; 0.0 L) and FS (WMD: 3.157, 95% CI: 2.218 to 4.097, P &lt; 0.001, I2: 81.3%, P &lt; 0.001).DiscussionThe results show that the pre-administration of saponins from TCM has a significant protective effect on MIRI in preclinical studies, which provides an application prospect for developing anti-MIRI drugs with high efficiency and low toxicity.
Estimation of life's essential 8 score with incomplete data of individual metrics
Authors: Zheng Yi , Huang Tianyi , Guasch-Ferre Marta , Hart Jaime , Laden Francine , Chavarro Jorge , Rimm Eric , Coull Brent , Hu Hui 
Published: July 2023

BackgroundThe American Heart Association's Life's Essential 8 (LE8) is an updated construct of cardiovascular health (CVH), including blood pressure, lipids, glucose, body mass index, nicotine exposure, diet, physical activity, and sleep health. It is challenging to simultaneously measure all eight metrics at multiple time points in most research and clinical settings, hindering the use of LE8 to assess individuals' overall CVH trajectories over time.Materials and methodsWe obtained data from 5,588 participants in the Nurses' Health Studies (NHS, NHSII) and Health Professionaĺs Follow-up Study (HPFS), and 27,194 participants in the 2005–2016 National Health and Nutrition Examination Survey (NHANES) with all eight metrics available. Individuals' overall cardiovascular health (CVH) was determined by LE8 score (0–100). CVH-related factors that are routinely collected in many settings (i.e., demographics, BMI, smoking, hypertension, hypercholesterolemia, and diabetes) were included as predictors in the base models of LE8 score, and subsequent models further included less frequently measured factors (i.e., physical activity, diet, blood pressure, and sleep health). Gradient boosting decision trees were trained with hyper-parameters tuned by cross-validations.ResultsThe base models trained using NHS, NHSII, and HPFS had validated root mean squared errors (RMSEs) of 8.06 (internal) and 16.72 (external). Models with additional predictors further improved performance. Consistent results were observed in models trained using NHANES. The predicted CVH scores can generate consistent effect estimates in associational studies as the observed CVH scores.ConclusionsCVH-related factors routinely measured in many settings can be used to accurately estimate individuals' overall CVH when LE8 metrics are incomplete.