bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Deep Neural Network Modeling Methodology for Extraction of RLGC Parameters in µ-wave and mm-wave Transmission Lines
Authors: Newberry Stephen , Zadehgol Ata 
Published: April 2023

<p>Transmission line geometry is one of the most critical aspects of high-speed digital and radio frequency (RF) printed circuit board (PCB) design. While relatively simple equation-based methods exist to estimate transmission line parameters such as characteristic impedance, they do not hold accuracy beyond certain structural limitations such as track width to dielectric thickness ratios. Electromagnetic field solvers have become far more common in recent times and can deliver exceptional accuracy with relatively low computational cost. This paper describes a proof-of-concept neural net which utilizes five input parameters of an uncoated microstrip transmission line and is able to output the per-unit-length equivalent resistance, inductance, conductance, and capacitance RLGC parameters. The goal of a deep-learning based transmission line tool is to enable accurate microstrip and stripline PCB trace design with computation speeds which allow the engineer to compute hundreds or thousands of iterations in a short period of time with commodity hardware. The final model calculates characteristic impedance with less than ±1.33 Ω error for 100,000 swept samples when the samples are within the middle 90% range of the training data and with a computation speed increase of 14.5 times faster than the benchmark field solver.</p>
Enabling New Generation Services with Multi-Level Delegation Architecture of Slicing Technology
Authors: Dandoush Abdulhalim , Kammoun Amal , diaz gladys , achir nadjib , Tabbane Nabil 
Published: April 2023

<p>5G/6G network slicing is identified as key enabler technology for allowing a diversity of sustainable applications while satisfying user’s requirements. A major problem of the traditional networking technologies is the use of the ”one size fits all” approach that handles all types of services. In this work, we focus on drawing a new architecture born of the need of a multi-level services’ orchestration for seeking flexible intelligent management of the new generation use-cases such as massively deployed cloud and edge-cloud based IoT applications for (i) environment monitoring, (ii) Agriculture development, (iii) and new generation Augmented Reality applications in medicine or e-learning.Thispaperproposesanovelmulti-levelDelegationArchitecture for Network Slicing Orchestration (DANSO). DANSO proposes a multi-level delegation for slices management and optimization framework for resources allocation. Our proposal is based on three pillars: (i) definition of levels to fulfill support of network slicing deployment and management via delegated decisions (ii) split of orchestrator, manager and control roles and (iii) placement-independence of entities in (ii). DANSO has the following advantages. First, it provides an optimization mechanism for the deployment of network slices. second, it takes into consideration a negotiation process for the requested slice. Third, it manages the life-cycle not only for the Virtual Network Function (VNF) level but also for the dynamic deployment and suppression of the whole slices. last, it considers network slicing over several administrative domains. </p>
Antígeno del factor von Willebrand (FVW:Ag)/ Actividad del cofactor de ristocetina (FVW:RCo)/ Multímeros de factor von Willebrand
Authors: Vizcaíno-Carruyo Jennifer C. , Pérez-Monterrosa María Elena , Toro-Montoya Ana Isabel , Franco-Alzate Catalina 
Published: April 2023

La utilidad principal de la prueba antígeno del FVW (FVW:Ag) es diagnosticar la enfermedad de von Willebrand (EVW), la cual es un trastorno hemorrágico causado por una reducción o alteración cualitativa del FVW, que puede ser hereditario en la mayoría de los casos, o adquirido cuando es secundario a otras patologías. Por su parte, la prueba FVW:RCo mide la capacidad del FVW de aglutinar plaquetas exógenas normales fijadas en formaldehído, ante la presencia del cofactor antibiótico ristocetina. La cantidad de aglutinación inducida por la ristocetina está directamente relacionada con la concentración del FVW, y se determina como porcentaje de actividad a través de un agregómetro. Finalmente, la prueba de multímeros de factor von Willebrand se basa en la técnica de electroforesis e inmunofijación en gel de agarosa, que permite evaluar la distribución y presencia de los multímeros del FVW en el plasma de acuerdo a su peso molecular. En el gel, los multímeros son separados e inmunoprecipitados con un antisuero específico anti-FVW. La utilización de un anticuerpo marcado con peroxidasa y un substrato específico, hace que se puedan visualizar las diferentes bandas en el gel.
Distribution and antifungal resistance rate of yeast isolated from various samples
Authors: Özbek Erdal , Bagi Azarkan Ayşe , Temiz Hakan , Atmaca Selehattin 
Published: April 2023

Objective: Yeast causes hospital-acquired infections at increasing rates, which can cause serious mortality, especially in patients with a suppressed immune system. This study aimed to determine the species distribution and antifungal resistance rates of yeast isolated in a hospital.
Material and Methods: Isolated yeasts from clinical specimens of patients who received inpatient treatment in different clinics in our hospital between 1 December 2019 and 30 September 2020 were examined. In all of these isolates, species identification was made with an automated system in addition to classical methods. Additionally, the antifungal susceptibility of yeast against amphotericin B, flucytosine, Fluconazole, micafungin, caspofungin, and Voriconazole was investigated using an automated system.
Results: In the study, yeasts isolated from 183 clinical samples, including 64 vagen, 62 blood, 28 urine, 12 wounds, eight tracheal aspirates, five peritoneal fluids, three catheters and one cerebrospinal fluid (CSF) samples were included. Of these isolates, 93 were Candida albicans (50,82%), 40 were Candida parapsilosis (21,86%), 17 were Candida tropicalis (9,29%), eight were Candida glabrata (4,37%), eight were Stephanoascus ciferrii (4,37%), five were Candida lusitaniae (2,19%), four were Candida famata (2,19%), four were Cryptococcus laurentii (2,19%) and four were Candida krusei ( 2,19%). Antifungal susceptibility testing was performed in 103 of the isolates. The highest resistance was found against Fluconazole, with 16.8%, and the lowest resistance was against flucytosine, with 2.2%. Antifungal resistance rates of Fluconazole, Voriconazole, amphotericin B, flucytosine, caspofungin and micafungin were found as 16.8%, 8.2%, 6.1%, 2.2%, 2.9% and 6.8% respectively.
Conclusion: Due to the increasing frequency of fungal infections due to long-term hospitalization, it has been concluded that identifying the causative species and reporting the antifungal susceptibility status is important in monitoring the change in resistance rates and guiding the treatment.
The role of macrophages, myeloperoxidase, interleukins IL-12, IL-13 in the formation of bronchial response to hyperosmolar stimulus in patients with bronchial asthma
Authors: Pirogov A. B. , Prikhodko A. G. 
Published: April 2023

Introduction.The involvement of macrophages in the realization of oxidative / halogenating stress andthe role of macrophage populations in maintaining the balance of Th1/Th2 cytokines in patients with asthma with osmotic types of bronchial hyperresponsiveness has not been sufficiently studied.Aim.To study the role of macrophages, myeloperoxidase (MPO), IL-12, IL-13 in the formation of the bronchial response to the hyperosmolar trigger in patients with asthma.Materials and methods. The object of the study was asthma patients (n=35). The level of asthma control (Asthma Control Test, points), cellular composition (%) and MPO (pixel) of induced sputum (IS), bronchial response (ΔFEV1IHS, %) after 3-minute ultrasonic inhalation of hypertonic (4.5% NaCl) solution (IHS) were assessed. Before and after the IHS test, exhaled air condensate was collected, in which the concentration of IL-12, IL-12 (pg/mL) was determined.Results.Patients with asthma did not control the disease, ACT was 14 (11; 16.5) points. Group 1 (n=15) included individuals with bronchial hyperresponsiveness to the IHS, group 2 (n=20) included patients with lack of it (ΔFEV1IHS-19.8±1.9 and 1.43±0.72%, respectively, p<0.001). Baseline FEV1 in groups 1 and 2 was 89.5±2.8 and 93.7±2.3%, respectively (p>0.05). The percentage of sputum macrophages in group 1 was lower (40 [15.95; 50.75]%), and the average cytochemical coefficient in phagocytes was higher (141.4±9.7) than in group 2 (50 [42.5; 63.6]; p=0.039 and 98.8±12.3; p=0.013, respectively). IL-12 expression was to be more significant than IL-13 expression in the initiation of airway inflammation and hyperresponsiveness to hyperosmolar stimulus.Conclusion.The lower concentration of macrophages in the bronchi of asthma patients with airway hyperresponsiveness to hyperosmolar stimulus is most likely due to an increase in the secretory function of cells. A high level of MPO activity in these patients depended on the peroxidase function of secreting macrophages, was associated with M1 polarization of macrophages, and indicated a Th1 immune response associated with the participation of IL-12 in the regulation of airway hyperresponsiveness to a hypertonic trigger.
UPAYA MENINGKATKAN PEMAHAMAN PESERTA DIDIK KELAS IV MATERI GAYA DENGAN RANCANGAN UNDERSTANDING BY DESIGN (UbD) MELALUI PENERAPAN MODEL RADEC
Authors: Saodah Siti , Mulyasari Effy , Anggia Rahman Gunawan 
Published: April 2023

Penelitian ini bertujuan untuk mengetahui penerapan model RADEC terhadap peningkatan pemahaman peserta didik dalam pembelajaran IPA. Penelitian ini adalah penelitian tindakan kelas kolaboratif yang terdiri dari 2 siklus yaitu siklus 1 dan siklus 2. Metode yang digunakan yaitu kuantitatif pre-eksprimen dengan desain one-grup pretest-posttest dalam rancangan Understanding by Design (UbD). Subjek penelitian adalah peserta didik kelas IV di SDN 037 Sabang yang berjumlah 28 orang, yaitu 15 laki-laki dan 13 perempuan. Teknik sampel menggunakan simple random sampling. Pengambilan data menggunakan instrumen tes soal kemampuan pemahaman pretest-posttest dan lembar observasi. Hasil penelitian diperoleh nilai rata-rata pretest siklus 1 dan 2 sebesar 38, posttest siklus 1 sebesar 72 dan siklus 2 sebesar 81. Pengolahan data dianalisis menggunakan Ms. Excel dengan uji Paired Sample t-test pada α (0,05) dan diperoleh nilai t hitung (11,77) < t tabel (2,059) pada siklus 1 dan t hitung (15,61) < t tabel (2,059) pada siklus 2. Hal ini menunjukan bahwa terdapat perbedaan yang signifikan antara pretets dan posttest. Nilai N-gain yang diperoleh sebesar 0.5356 pada siklus ke-1 dan 0.6802 pada siklus ke-2 dengan kategori sedang. Hasil lembar observasi pemahaman peserta didik pada siklus 1 dan 2 diperoleh persentase peningkatan kemampuan pemahaman dengan indikator menjelaskan 17,78%, aplikasi 11,57%, perspektif 16,21%, berempati 12,96%, dan mencipta 18,21%. Hal tersebut menunjukan adanya peningkatan pemahaman peserta didik dengan menggunakan model RADEC.
Tolvaptan to Achieving High Urine Output and Avoiding Hyponatremia in COVID-19 with ADHF Patient: Case Report
Authors: Puradipa I Made Bayu , Sinardja Cyndiana Widia Dewi 
Published: April 2023

Background: Pandemic of Coronavirus Disease 2019 (COVID-19) is a world health problem, with rapidly growing infected subjects. Recently, hyponatremia has been found to be associated with increased morbidity and mortality in hospitalized patients with severe acute respiratory syndrome-Coronavirus 2 (SARS-COV2) pneumonia. On the other hand, Acute heart failure (AHF) is a leading cause of hospitalization and readmission in the US. The standard management of AHF is removing the fluid primarily with loop diuretics or ultrafiltration. Unfortunately, the loop diuretics could lead to electrolyte imbalance.
Case Description: A Male 71 years old with confirmed COVID-19 came to emergency room with shortness of breath and history of coronary artery disease (CAD). Unfortunately, the infection leads patient to non-ST Elevation Myocardial Infarction (NSTEMI). During the treatment, patient down to acute decompensated heart failure (ADHF). The congestion did not respond to Furosemide 40mg intravenously and Spironolactone 25mg orally.
Discussion: Arginine‑vasopressin (AVP) levels are elevated in heart failure. AVP acts via V2 cause fluid retention and hyponatremia. Aquaretic (i.e., Tolvaptan) are antagonists of AVP-2 receptors in the renal tubules to promote solute-free water clearance and correct hyponatremia.
Conclusion: Important to avoid hyponatremia to prevent mortality and sepsis in patient COVID-19.
A CASE REPORT ON CERVICAL ECTOPIC PREGNANCY
Authors: Malireddi Ramya , Matcha Mounica , Vedurupaka Sushmasri , Murre Abhishek , Kumar Amit , Y.Annapoorna  
Published: April 2023

Ectopic Pregnancy also termed as extrauterine pregnancy in which the fertilised egg implantation occurs outside the uterus. Cervical ectopic pregnancy is one of the rarest form with an incidence of less than 0.1%.Cervical ectopic pregnancy is life threatening due to the high risk of bleeding if it is not treated correctly. It can be diagnosed through symptoms, ultra sound imaging and serum Hcg levels. Symptoms include bleeding and pelvic pain. Methotrexate is the drug of choice, but still there is no consensus on the most appropriate treatment for this abnormal pregnancy. In this case we discussed about a 30years old pregnant woman presented with chief complaints of bleeding, white discharge, burning micturition and a known case of diabetes and hypertension.
EPIDEMIOLOGICAL AND CLINICAL ASPECTS OF RETINOBLASTOMA IN DEVELOPING COUNTRY
Authors: Randrianarisoa Hoby Lalaina  , RAKOTOARISOA Rivo Tahiry Rabetafika , Andriambelo RH  , S Raonintsoa , NML Rakotomahefa , L Raobela 
Published: April 2023

Introduction:
Retinoblastoma is the most common intraocular tumor in child. Treatment depend on stadification and classification of retinoblastoma. The aim of this study was to describe epidemiological and clinical aspects of retinoblastoma in Madagascar.
Method: We report in this retrospective study 44 cases found during 5 years, from January 2015 to December 2019. We have collected information about epidemiological and clinical aspect, delay of diagnosis. Classification of retinoblastoma was done with Reese Ellsworth classification and International Classification of Intra-ocular Retinoblastoma (ICRB). Data was collected with excel software and analysis was done with R-studio 4.2.2 software. The quantitative variables were expressed as an average and the qualitative variables as a proportion and percentage.
Result: We had collected 44 cases. The incidence was 8.8 cases per year. Sex ratio was 1.3. Mean age was 40 months. Exophthalmos was found in 35% (n=12) of cases. Leukocoria was found in 24% (n=11) children. The delay time before diagnosis was 13 months. In 97.7% of cases, the retinoblastoma was unilateral. Intraocular form was found in 23 patients (52.3%). Among intraocular form 13 patients (57%) presented with grade E, including one patient with meningeal extension 9 patients (39%) with grade D, 1 patient (4%) in grade B. Extra ocular form was found in 21 patients (47.7%) : 17 (77%) had orbital invasion (stage III), 4 (23%) were metastatic (stage IV).
Conclusion: Diagnosis of retinoblastoma was made in advanced stage. Most of patients had extraocular form. Prognosis was worse in Madagascar. Making diagnosis early is necessary to prevent loss of life.
جريمة الاختلاس بين أحكام الشريعة الإسلامية وقانون الوقاية من الفساد ومكافحته
Authors: لحمر نعيمة 
Published: April 2023

Le détournement est la manière la plus efficace de s’emparer du bien public ce crime est le plus répondu et destructeur en comparaison avec les autres crimes de corruption cela est du à la gérance directe de ce dernier par les fonctionnaires ce statut leur permet de s’emparer facilement de l’argent public.
En réalité ce crime est devenu un fléau qui se propage dans le corps des fonctionnaires qui utilisent leurs responsabilités à des fins personnels au lieu de servir la société que le législateur a protégé ses intérêts contre toute agression.
En conséquence, le législateur algérien par le biais de l’article 29 de la loi 06 / 01 qui a remplacé l’article 119 du code pénale qui a été abrogé relatif à la prévention et la lutte contre la corruption.
Ceci dans le but de lutter contre tout fraude et dépassement du fonctionnaire afin qu’il ne perde sa crédibilité et sa solvabilité.
Validation and Testing of the CROBAR 3D Coronal Reconstruction Method with a MURaM Simulation
Authors: Plowman Joseph 
Published: April 2023

Abstract
I report on validation and testing of a novel 3D reconstruction method than can obtain coronal plasma properties from a single snapshot perspective. I first reported on the method in 2021, and I have since named it the Coronal Reconstruction Onto B-Aligned Regions (CROBAR) method. The testing and validation are carried out with a cube from a MURaM 3D MHD simulation, which affords a coronal-like “ground truth” against which the reconstruction method can be applied and compared. I find that the method does quite well, recovering the “coronal veil”−like features recently reported from the MURaM simulations and allaying concerns that these features would thwart recovery of valid 3D coronal structure from a limited number of perspectives. I also find that a second perspective between ∼45° and 90° does significantly improve the reconstructions. Two distinct channels with soft-X-ray-like temperature response (peaking above 5 MK) would suffice for CROBAR’s optically thin observables A suite of AIA-like EUV passbads, with good coverage in the 3–8 MK range, is also well suited to CROBAR.
Total Keratometry Measured With a Swept-Source Optical Biometer Versus Anterior Keratometry: From Planning to Postoperative Results
Authors: Anjou Mickael , Brezin Antoine , Monnet Dominique 
Published: April 2023

Purpose:
To compare the influence of total keratometry (TK) versus anterior keratometry (K) measured with the swept-source optical biometer IOLMaster 700 (Carl Zeiss Meditec AG) on the planning of toric intraocular lenses (IOLs), and the error in predicted residual astigmatism (PRA).

Methods:
This single-center retrospective study included 247 eyes of 180 patients. In eyes undergoing cataract surgery, the optimal toric IOL was calculated based on K or TK measured with the IOLMaster 700. Two formulas were used to estimate IOL power: Holladay and Barrett Toric. Optimal cylinder power and alignment axis change induced by using TK versus K were reported. PRA by each calculation method was compared with manifest refractive astigmatism. Postoperative refractive astigmatism prediction error was calculated using vector analysis.

Results:

The optimal toric IOL based on TK compared with K was different in 39.3% of cases with the Holladay formula and 31.6% of cases with the Barrett Toric formula. The use of TK rather than K reduced the centroid error in PRA when calculated with the Holladay formula (
P
< .001), but not when calculated with the Barrett Toric formula (
P
= .19). The against-the-rule astigmatism subgroup analysis with the Barrett Toric formula showed a statistically significant decrease of centroid error in PRA with the use of TK compared with K (
P
= .01).

Conclusions:
TK compared with K measured with the IOL-Master 700 resulted in a change of optimal toric IOL in almost one-third of cases and decreased the error in PRA in patients with against-the-rule astigmatism.

[
J Refract Surg
. 2023;39(4):257–264.]
Visual and Refractive Outcomes of a Trifocal Toric Intraocular Lens Implanted in Eyes With High Corneal Astigmatism
Authors: Ruiz-Mesa Ramón , Tañá-Sanz Pedro , Tañá-Sanz Santiago , Orts-Vila Paz , Tañá-Rivero Pedro 
Published: April 2023

Purpose:
To analyze the refractive and visual outcomes following cataract surgery and implantation of a trifocal toric intraocular lens (IOL) in eyes with high degrees of corneal astigmatism.

Methods:
A total of 29 eyes from 21 patients who underwent implantation of a trifocal toric IOL (FineVision PODFT; PhysIOL) were evaluated in this study. Phacoemulsification with femto-second laser and intraoperative aberrometry were performed in all cases. All IOLs used exhibited a cylinder power of 3.75 diopters (D) or greater. The main outcome measures were refractive error and corrected distance visual acuity (CDVA) and uncorrected distance visual acuity (UDVA) values. Eyes were evaluated during a follow-up period of 5 years.

Results:
A total of 96.30%, 100%, 95.83%, and 89.47% of eyes were within ±1.00 D at 1, 2, 3, and 5 years postoperatively, respectively. Furthermore, 92.31%, 86.36%, 82.61%, and 84.21% of eyes showed a refractive cylinder value of ±1.00 D at 1, 2, 3, and 5 years postoperatively, respectively. During the entire follow-up period, between 81.48% and 91.30% of eyes showed a CDVA of 20/25 or better. The mean monocular Snellen decimal CDVA values were 0.90 ± 0.12, 0.90 ± 0.11, 0.91 ± 0.11, and 0.90 ± 0.12 at 1, 2, 3, and 5 years postoperatively, respectively. No significant rotation was reported in any eye during follow-up.

Conclusions:
The current study suggests that use of this trifocal toric IOL in eyes with high amounts of corneal astigmatism provides accurate refractive outcomes with good distance visual acuity.

[
J Refract Surg
. 2023;39(4):229–234.]
Long-term Clinical Outcomes After Trifocal Intraocular Lens Implantation: A Retrospective Observational Study
Authors: Jeon Sohee , Moon Kun , Kwon Hyunggoo 
Published: April 2023

Purpose:
To evaluate the long-term stability of the AcrySof IQ PanOptix TFNT00 intraocular lens (IOL) (Alcon Laboratories, Inc).

Methods:
This was a retrospective review of 1,065 eyes (745 patients) who underwent implantation of a PanOptix IOL. A total of 296 eyes (mean age: 58.62 ± 5.63 years and preoperative refractive error: −0.68 ± 3.01 diopters [D]) met inclusion criteria for this study. The objective refraction, uncorrected distance and near visual acuity (UDVA and UNVA), and corrected distance visual acuity (CDVA) were evaluated at postoperative months 1, 2, 6, 12, 24, and 36.

Results:

The refractive error was −0.20 ± 0.36 D at 1 month, −0.20 ± 0.35 D at 2 months (
P
= .503), −0.10 ± 0.37 D at 6 months (
P
< .001), −0.02 ± 0.38 D at 12 months (
P
< .001), 0.00 ± 0.38 D at 24 months (
P
< .001), and 0.03 ± 0.39 D at 36 months (
P
< .001). Multivariate analysis showed long-term, independent associations for young age (beta = −0.122;
P
= .029) and changes in mean keratometry (beta = −0.413;
P
< .001). A greater refractive change was associated with a greater change in UNVA (
r
= 0.134;
P
= .026) but not with UDVA (
r
= −0.029;
P
= .631) or CDVA (
r
= −0.010;
P
= .875).

Conclusions:
Implantation of the PanOptix IOL yields stable clinical outcomes for visual acuity and refractive error for the first 3 years. A slight hyperopic shift, causing decreased near visual acuity, is anticipated for younger patients.

[
J Refract Surg
. 2023;39(4):236–241.]