bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migräne in speziellen hormonellen Situationen
Authors: Segerer Sabine , Evers Stefan , Israel-Willner Heike , Raffaelli Bianca 
Published: May 2023

ZUSAMMENFASSUNGBei der menstruellen Migräne gibt es verschiedene spezifische Therapieoptionen. So kann ca. 4–5 Tage vor dem erwarteten Menstruationsbeginn ein Östradiolpflaster mit 50 µg pro Tag für wenigstens 7 Tage als Kurzzeitprophylaxe ausprobiert werden; bei Unwirksamkeit kann dies mit 100 µg pro Tag wiederholt werden. Eine hormonelle Kontrazeption mit einem Mischpräparat oder Mehrphasenpräparat kann probatorisch abgesetzt werden. In besonderen Fällen ist eine durchgehende hormonelle Kontrazeption bis zu 2 Jahre sinnvoll.Patientinnen mit Migräne und Endometriose zeigen während der Menstruation höhere CGRP-Werte als in der Zyklusmitte, wohingegen dies bei Frauen ohne Migräne und Kontrollprobandinnen umgekehrt ist. Dies deutet auf eine mögliche Rolle von CGRP in den perimenstruellen Schmerzattacken hin. Weiterhin ist die Lebensqualität bei Patientinnen mit Migräne und Endometriose deutlich stärker beeinträchtigt als bei nur einer Erkrankung. Daher ist es klinisch relevant, diese Komorbidität zu berücksichtigen.Eine hormonelle Frau-zu-Mann-Transition geht mit signifikant mehr Kopfschmerzen einher als die umgekehrte Transition. Bei der Mann-zu-Frau-Transition scheint sich dagegen häufiger eine Migräne zu bilden, insbesondere mit Aura. Die Behandlung der Kopfschmerzen und der Migräne erfolgt wie bei anderen Betroffenen auch, allerdings muss die erhöhte Thromboseneigung durch die Hormonbehandlung berücksichtigt werden.
Ökologische Transformation der medizinischen Rehabilitation:
Was können wir wissen und was müssen wir tun?
Authors: Worringen U , Becker P , Reusch A , Küffner R , Reudelsterz C , Pawel A , Weimann E. 
Published: May 2023

ZusammenfassungKlimakrise und schwindende Biodiversität haben auch eine Bedeutung
für die medizinische Rehabilitation in Deutschland.
Rehabilitationseinrichtungen haben zum einen die Folgen der Naturzerstörung
und des Wildtierhandels zu bewältigen, tragen zum anderen aber durch ihr
Verhalten auch zur Erderwärmung und abnehmenden Artenvielfalt bei. National
und international wurden in den letzten Jahrzehnten Handlungsstrategien entwickelt,
um die Klimakrise auszubremsen und deren Folgen zu mildern.
Rehabilitationseinrichtungen haben nur noch wenige Jahre Zeit, um ihren Anteil zu
leisten, der irreversiblen Vernichtung unserer natürlichen Lebensgrundlagen
entgegenzuwirken. Die Deutsche Rentenversicherung als Kosten- und
Leistungsträger der medizinischen Rehabilitation kann die
Rehabilitationseinrichtungen bei dieser großen Herausforderung finanziell
und strategisch unterstützen. Gelingt die ökologische Transformation
nicht, wird Krisenmanagement auch den Rehabilitationsalltag langfristig
bestimmen.
Early Muscle MRI Findings in a Pediatric Case of Emery-Dreifuss Muscular Dystrophy Type 1
Authors: Panicucci Chiara , Casalini Sara , Traverso Monica , Brolatti Noemi , Baratto Serena , Raffaghello Lizzia , Pedemonte Marina , Doglio Luca , Derchi Maria , Tasca Giorgio , Damasio Beatrice M. , Fiorillo Chiara , Bruno Claudio 
Published: May 2023

AbstractEmery-Dreifuss muscular dystrophy (EDMD) is a rare disease characterized by early contractures, progressive muscle weakness, and cardiac abnormalities. Different subtypes of EDMD have been described, with the two most common forms represented by the X-linked EDMD1, caused by mutations in the EMD gene encoding emerin, and the autosomal EDMD2, due to mutations in the LMNA gene encoding lamin A/C. A clear definition of the magnetic resonance imaging (MRI) pattern in the two forms, and especially in the rarer EDMD1, is still lacking, although a preferential involvement of the medial head of the gastrocnemius has been suggested in EDMD2. We report a 13-year-old boy with mild limb girdle muscle weakness, elbow and ankle contractures, with absence of emerin at muscle biopsy, carrying a hemizygous frameshift mutation on the EMD gene (c.153dupC/p.Ser52Glufs*9) of maternal inheritance. Minor cardiac rhythm abnormalities were detected at 24-hour Holter electrocardiogram and required β-blocker therapy. MRI scan of the thighs showed a mild diffuse involvement, while tibialis anterior, extensor digitorum longus, peroneus longus, and medial gastrocnemius were the most affected muscles in the leg. We also provide a review of the muscular MRI data in EDMD patients and highlight the relative heterogeneity of the MRI patterns found in EDMDs, suggesting that muscle MRI should be studied in larger EDMD cohorts to better define disease patterns and to cover the wide disease spectrum.
Eco-tourism, climate change, and environmental policies: empirical evidence from developing economies
Authors: Shang Yunfeng , Bi Chunyu , Wei Xinyu , Jiang Dayang , Taghizadeh-Hesary Farhad , Rasoulinezhad Ehsan 
Published: May 2023

AbstractDeveloping ecotourism services is a suitable solution to help developing countries improve the status of sustainable development indicators and protect their environment. The primary purpose of this paper is to find out the effects of green governance variables and carbon dioxide emissions on ecotourism for 40 developing economies from 2010 to 2021. The results confirmed a uni-directional causal relationship between the green governance indicator and the inflation rate of the ecotourism indicator. In addition, with a 1% improvement in the green governance index of developing countries, the ecotourism of these countries will increase by 0.43%. In comparison, with a 1% increase in the globalization index of these countries, ecotourism will increase by 0.32%. Moreover, ecotourism in developing countries is more sensitive to macroeconomic variables changes than in developed economies. Geopolitical risk is an influential factor in the developing process of ecotourism. The practical policies recommended by this research are developing the green financing market, establishing virtual tourism, granting green loans to small and medium enterprises, and government incentives to motivate active businesses.
Influence of the charge transport layers on charge extraction and interface recombination in quasi-two-dimensional perovskite solar cells
Authors: Ling Qin , Dai Qing , Yang Liu , Wang Xu , Huang Like , Liu Xiaohui , Zhang Houcheng , Zhang Jing , Zhu Yuejin , Hu Ziyang 
Published: May 2023

Abstract
The identification of electronic processes at the charge-selective contact buried interface is very important for photovoltaic research. The main loss of perovskite solar cell (PeSCs) is generally bound up with its charge transfer layer. Especially, the current record for the highest power conversion efficiency of quasi-two-dimensional (quasi-2D) PeSCs is achieved by inverted device configurations, compared with the efficiency of upright structures. This study investigated, the carrier recombination and charge extraction in quasi-2D PeSCs by leveraging scanning probe microscope technology, steady-state photoluminescence (PL) measurements, and time-resolved PL spectroscopy. The built-in potential in quasi-2D bulk perovskite can be regarded as a budget to hinder energy loss in inverted device configurations. Interface photogenerated recombination in quasi-2D PeSCs can be fully comprehended only when the complete device is under consideration. Our work underlines the significance of considering restructuring loss from the perspective of the complete device instead of individual layers or interfaces in quasi-2D PeSCs.
XQC and CSR constraints on strongly interacting dark matter with spin and velocity dependent cross sections
Authors: Li Yonglin , Liu Zuowei , Xue Yilun 
Published: May 2023

Abstract
Dark matter that interacts strongly with baryons can avoid the stringent dark matter
direct detection constraints, because, like baryons, they are likely to be absorbed when
traversing the rocks, leading to a suppressed flux in deep underground labs. Such strongly
interacting dark matter, however, can be probed by dark matter experiments or other experiments
operated on the ground level or in the atmosphere. In this paper we carry out systematic analysis
of two of these experiments, XQC and CSR, to compute the experimental constraints on the strongly
interacting dark matter in the following three scenarios: (1) spin-independent and spin-dependent
interactions; (2) different velocity dependent cross sections; (3) different dark matter mass
fractions. Some of the scenarios are first analyzed in the literature. We find that the XQC
exclusion region has some non-trivial dependencies on the various parameters and the limits in the
spin-dependent case is quite different from the spin-independent case. A peculiar region in the
parameter space, where the XQC constraint disappears, is also found in our Monte Carlo
simulations. This occurs in the case where the interaction cross section is proportional to the
square of the velocity. We further compare our XQC and CSR limits to other experimental
constraints, and find that a large parameter space is allowed by various experiments if the dark
matter mass fraction is sufficiently small, fχ
≲ 10-4.
Inferring redshift and energy distributions of fast radio bursts from the first CHIME/FRB catalog*
Authors: Tang Li , Lin Hai-Nan , Li Xin 
Published: May 2023

Abstract
We reconstruct the extragalactic dispersion measure – redshift (

) relation from well-localized fast radio bursts (FRBs) using Bayesian inference. Then, the

relation is used to infer the redshift and energy of the first CHIME/FRB catalog. We find that the distributions of the extragalactic dispersion measure and inferred redshift of the non-repeating CHIME/FRBs follow a cut-off power law but with a significant excess at the low-redshift range. We apply a set of criteria to exclude events that are susceptible to the selection effect, but the excess at low redshifts still exists in the remaining FRBs (which we call the gold sample). The cumulative distributions of fluence and energy for both the full sample and the gold sample do not follow the simple power law, but they can be well fitted by the bent power law. The underlying physical implications require further investigation.
High-power Fixed-Field Accelerators
Authors: Winklehner D , Adelmann A. , Alonso J.R , Calabretta L , Okuno H , Planche T , Haj Tahar M 
Published: May 2023

Abstract
We report the state of the field of High-Power Fixed-Field
Accelerators (with an emphasis on cyclotrons) as discussed by
international experts during a three-day workshop of the same name
in 2021. The workshop was part of the Snowmass'21 Community
Planning Exercise. Here, we take stock of the world inventory of
high-power fixed-field accelerators, assess available beam currents
and beam powers, and investigate limitations. Furthermore, we
evaluate the role of these machines in particle physics,
directly used or as injectors to other machines, and in industry, as
drivers for (medical) isotope production and, potentially, for
accelerator-driven systems and sub-critical reactors. Finally, we
discuss novel concepts and cutting-edge developments to push the
available current higher at several energy scales, thereby
increasing relative power. Highlights include new spiral inflector
types, direct RFQ injection, H2
+ acceleration,
utilizing vortex motion, and self-extraction schemes. We also
discuss modern computational frameworks to optimize accelerators
more efficiently, and better describe the relevant physical
processes in simulations.
Green Agriculture and Food Security, a Review
Authors: Nwachukwu C. S. 
Published: May 2023

Abstract
Green Agriculture is sustainable farming based on environment conservative philosophies, policies and practices to prevent the degrading of the ecosystem and as such, a traditionally subsistent agricultural-mindset that aims at achieving food security. Green Solutions (GS) in agriculture for food security therefore, is the concept that focuses on environmental sustainability and guides business activities against disruption of nature’s ecological system and biodiversity while ensuring that population growth is unaffected by hunger and food price inflation. The objective of this paper is to enquire on the relevance and feasibility of Green solutions in agriculture to optimally secure the ecosystem in a changing global economy without hunger in the ever increasing world’s population. This research used secondary data in a descriptive research and found that Green Agriculture is improved through sustainable green technological advancement in food production, where renewable energy and organic fertilizers power adequate agricultural productions. The research found that food security for ever-increasing global population therefore, constantly demands a global green solutions’ HMSA-1 (hybrid mode subsistence-agribusiness) concept, through research and development (R&D), for an improved sustainable green agriculture powered by renewable energy.
Equilibrium isotherm investigation on the sequestration of ciprofloxacin from solution via adsorption onto yam peel powder
Authors: Akpomie Kovo G , Ofomatah Anthony C , Chukwuemeka-Okorie Helen O , Ani Julius U , Agbo Sunday C , Odewole Olufemi A , Ojo Francis K , Alum Ogechi L. , Conradie Jeanet 
Published: May 2023

Abstract
In this work, the adsorption of ciprofloxacin onto yam peel biosorbent was studied by batch method. The equilibrium isotherm analysis of the adsorption process was evaluated to provide insight into the removal mechanism. A decrease in the percentage removal (75.0 – 60.8%) and an increase in adsorption capacity (6.0 – 24.3 mg/g) with an increase in ciprofloxacin concentration from 20 – 100 mg/L was obtained. The isotherm was analyzed by the Langmuir, Temkin, Freundlich, and Scatchard models, and the best fit was obtained for the Freundlich model with a R2 of 0.9918. The separation factor in the range of 0.238 – 0.609 and the Freundlich adsorption intensity of 1.492 indicated a favorable adsorption of ciprofloxacin on yam peel. A monolayer adsorption capacity of 42.81 mg/g was obtained for yam peel which was higher than other efficient adsorbents. The Scatchard model gave a linear fit to the uptake data with R2 of 0.9653 and sum square error of 0.008. The isotherm analysis revealed complex adsorption involving multi mechanisms in the overall process. The results of this investigation showed that yam peel could be utilized as an efficient agricultural waste for the adsorption of ciprofloxacin from wastewater.
Estimation of rain attenuation effect on radio wave propagation for broadband communication over northern Nigeria.
Authors: Orji P O , Chiemeka I U , Obiegbuna D C , Eze C M 
Published: May 2023

Abstract
Rain induced effect on propagated signal was studied in this work. The weather parameters of two (2) locations representing two (2) climate zones in Northern Nigeria were employed, using the International Telecommunications Union (ITU-R P.618) rain attenuation model, to investigate the rain effect on strength of propagated signal ranging from Ku-band to V-band of the communication spectrum. The weather data were obtained from the Nigerian Meteorological Agency (NIMET) for a period of 10years (2009-2018) and assimilated into the model using 1-minute integration time rain rate. An elevation angle of 42.5°, which is the conventional elevation angle of systems to NIGCOMSAT-1R over the Atlantic Ocean region, was used. The results showed that annual rainfall amounts trends varied slightly with the different locations and climate zones, having 2018 and 2010 as the highest rain years within the studied years at Maiduguri and Sokoto respectively. Also, the difference between maximum and minimum 0.01% attenuation for the two locations are 2dB-3dB, 3dB-6dB for horizontal polarization and 1dB-1.5dB and 2dB-4dB for vertical polarization respectively at the two locations respectively. Rain attenuation can be managed well for propagated Ku-band signal with sophisticated sensors but above Ku-band, signal strength attenuation induced by rain could be really alarming.
Measurements of Terrestrial Gamma Dose Rate Distributions along Idiroko Road, Ota, Ogun State, Nigeria: Health Implications on Roadside Dwellers
Authors: Omeje M. , Chijuo C. , Okafor I. F. , Adewoyin O. O. , Joel E. S. , Ekwueme B. N. , Nwankwo M. C. , Bello O. O. 
Published: May 2023

Abstract
An extensive study concerning the terrestrial gamma dose rates of the surface soils from Canaanland entrance Road, Ota to Eleha Complex along Idiroko Road, Ota has been carried out to cover the road running across both areas. The In-situ measurements of gamma dose rates and radionuclides were carried out using the Gamma detector (Super Spec RS 125). The result shows that the average outdoor gamma dose rate in the study area is 73.57 nGyh−1. The average values of the radionuclides obtained were 32.9 Bq/kg for 238U, 68.4 Bq/kg for 232Th, and 328.7 Bq/kg for 40K. The background dose rate of 113.3 nGy/h was found in station 9 and is twice higher than the recommended permissible limit of 59 nGy/h suggested by UNCSEAR, 2000, and ICRP, 1999, respectively. Results were obtained based on radiological parameters for the outdoor absorbed dose rate (Dout) with a mean value of 73.57 nGyh−1, the indoor absorbed dose rate (Din) with a mean value of 131.84 nGyh−1, the annual effective dose rate (AEDR) with a mean value of 0.74, the radium equivalent (Raeq) with a mean value of 156.0, the internal hazard index (Hin) with a mean value of 0.51, the external hazard index (Hex) with a mean value of 0.42 and the excess lifetime cancer risk (ELCR) with a mean value of 2.57. Similarly, results obtained from estimated radiological parameters show that the station with the highest value for radium equivalent (Raeq), external hazard index (Hex), internal hazard index (Hin), and annual effective dose rate (AEDR) is Station 9 at 237.91 Bq/Kg, 0.64, 0.72 and 1.13 mSvy−1 respectively while the station with the lowest value for radium equivalent (Raeq), external hazard index (Hex), internal hazard index (Hin) and annual effective dose rate (AEDR) is Station 17 at 85.58 Bq/Kg, 0.23, 0.27 and 0.40 mSvy−1 respectively. This study will serve as a guide on assessing the road construction materials on radioactive contents before application to reduce the exposure risks to the populace along the busy roadsides.
The influence of marinating with red ginger (Zingiber officinale var rubrum) biomass on the physical quality and sensory properties of buffalo meat
Authors: Patriani P , Rosadi  
Published: May 2023

Abstract
Red ginger has active chemical compounds that are beneficial for health. Besides being abundantly available, red ginger also has potential as a natural preservative. The content of active chemical compounds, antimicrobial activity, and protease enzyme support natural preservation methods in the food industry. This study aimed to determine the effect of red ginger concentration on the physical and organoleptic qualities of buffalo meat. The research method was experimental using a completely randomized design with 4 treatments and 5 replications. The treatment consisted of R0 = 0%; R1 = marinade using 20% red ginger concentration; R2 = marinade using 40% red ginger concentration; R3 = marinade using 60% red ginger concentration. The results showed that red ginger concentration had a significant effect (P<0.05) on cooking loss and colour. Red ginger concentration had a very significant effect (P<0.01) on the pH value, tenderness, and aroma but had no significant effect (P>0.05) on the water content of buffalo meat. This research concludes that marinating using red ginger biomass can improve the physical and sensory qualities of buffalo meat during storage. Red ginger biomass had the potential as a spice that can be applied sustainably to improve the buffalo meat quality.
Silica Synthesis from Oil Palm Mill Boiler Ash Under Different Concentration of NaOH and Extraction Time
Authors: Adha Firda Ferdianita , Warsiki Endang 
Published: May 2023

Abstract
Boiler ash from palm oil mill contains high SiO2compound. The boiler ash used in this study was from PKS Cikasungka PTPN VIII, Bogor. The research objectives were to (i) optimize the conditions of silica synthesis process from boiler ash, (ii) analyze the silica content of the synthesis, (iii) and analyze the performance of silica as a moisture absorber. This research was designed using a central composite design (CCD) and the variables were optimized using the response surface method (RSM), silica was synthesis using sol-gel method and silica content was measured using XRF. The performance of silica as a moisture absorber was also studied to determine the appropriate adsorption kinetics at 32%, 64%, 75%, 85% and 97% RH conditions. The results showed that the optimum process conditions that produced the highest silica yield (41.17%) were solvent concentration of 7.39 M and extraction time 78.13 minutes. The silica gel produced is a white powder with SiO2content of 79.20%. The results showed that the water vapor adsorption kinetics at 64% RH was simulated with a first order model, while other treatments with 32%, 75%, 85% and 97% RH were simulated with a second order pseudo model. At 32% RH had a higher k value of 0.086 g/g/day than the 97% RH of 0.011 g/g/day.
Determination of Chemical Content of Vanilla Pods (Vanilla planifolia) Non-destructively Using NIR Spectroscopy
Authors: Budiastra I W , Ramadhana H , Nurfadila N 
Published: May 2023

Abstract
This study aims to assess Near infrared (NIR) spectroscopy to predict vanillin and moisture content non-destructively. Twenty-four samples of vanilla pods (@55 grams/sample) from Sumatra and Sulawesi Island were tested. The reflectance spectra of vanilla pod were measured using a NIRFlex N-500 spectrometer at the wavelength of 1000-2500 nm. After that, the vanillin and moisture content were measured using the reference method. The reflectance spectra were transformed to absorbance spectra and several pre-treatment methods of NIR spectra were applied, and the results were calibrated with chemical data using principal component regression (PCR) and partial least square (PLS) methods. The best estimation for vanillin content using absorbance spectra with OSC pre-treatment at 3 PLS factors with the accuracy parameters of r = 0.91, SEC = 1.31%, SEP = 1.34%, CV = 45.60%, RPD = 2.30 with a consistency of 97.96%. The best prediction of vanillin content using PCR method was obtained with SNV pre-treated spectra at 6 PCR factors with the accuracy parameters of r = 0.89, SEC = 1.47%, SEP = 1.49%, CV = 43.21%, RPD = 2.09 and 101.40% consistency. The best estimation for water content using the PLS method is using the SNV pre-treatment spectra with a PLS factor of 5 with the accuracy parameters of r = 0.99, SEC = 2.11%, SEP = 2.13%, CV = 6.12%, RPD = 7.98 with consistency = 98.86%. While using the PCR method, the best estimation for moisture content was also obtained by SNV pre-treated spectra at 4 PCR factors with the accuracy values of r = 0.99, SEC = 2.33%, SEP = 2.25%, CV = 6.25%, RPD = 7.58 and consistency = 103.90%. The PLS calibration provide a better accuracy than the PCR. The NIR spectroscopy associated with the selected pre-treatments and factor numbers of PLS and PCR can be used for determination of chemical content of vanilla pods.