bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intention affects fairness processing: Evidence from behavior and representational similarity analysis of event‐related potential signals
Authors: Xu Qiang , Hu Jiali , Qin Yi , Li Guojie , Zhang Xukai , Li Peng 
Published: February 2023

AbstractIn an ultimatum game, the responder must decide between pursuing self‐interest and insisting on fairness, and these choices are affected by the intentions of the proposer. However, the time course of this social decision‐making process is unclear. Representational similarity analysis (RSA) is a useful technique for linking brain activity with rich behavioral data sets. In this study, electroencephalography (EEG) was used to measure the time course of neural responses to proposed allocation schemes with different intentions. Twenty‐eight participants played an ultimatum game as responders. They had to choose between accepting and rejecting the fair or unfair money allocation schemes of proposers. The schemes were offered based on the proposer's selfish intention (monetary gain), altruistic intention (donation to charity), or ambiguous intention (unknown to the responder). We used a spatiotemporal RSA and inter‐subject RSA (IS‐RSA) to explore the connections between event‐related potentials (ERPs) after offer presentation and intention presentation with four types of behavioral data (acceptance, response time, fairness ratings, and pleasantness ratings). The spatiotemporal RSA results revealed that only response time variation was linked with the difference in ERPs at 432–592 ms after offer presentation on the posterior parietal and prefrontal regions. Meanwhile, the IS‐RSA results found a significant association between inter‐individual differences in response time and differences in ERP activity at 596–812 ms after the presentation of ambiguous intention, particularly in the prefrontal region. This study expands the intention‐based reciprocal model to the third‐party context and demonstrates that brain activity can represent response time differences in social decision‐making.
Using the Ophelia (Optimising Health Literacy and Access to Health Services) process as a practical tool for health promotion program delivery in various Philippine communities
Authors: Tan Abigail Lim , Co Stephanie Anne L. , Modina Cheyenne Ariana Erika M. , Espinosa Christine Ingrid M. , Fowler Krizelle Cleo , Wong John Q. 
Published: February 2023

AbstractIssue AddressedThe Ophelia (Optimising Health Literacy and Access to Health Services) process can be used as a practical tool for effective health promotion program delivery because of its multi‐sector and pragmatic approach to designing health interventions. An initial case study showed how its first phase was successfully adapted in a pilot community in Leyte, Philippines. In this study, the three phases of the Ophelia process were implemented in Leyte, along with additional communities in Mindoro and Surigao.MethodsAfter conducting needs assessment and community profiling in phase 1, the results were transformed into vignettes, hypothetical personas representing the health needs of the community. These were used in phase 2, which involved focus group discussions and workshops to cocreate intervention ideas with government organisations, practitioners, and community representatives. A rapid realist review was conducted in phase 3 to check for the feasibility of interventions.ResultsThrough this, the top evidence‐based health interventions for each life stage were listed and presented for prioritisation. Program implementation and impact evaluation plans were created for the top health intervention prior to implementation.ConclusionsThe Ophelia process ensured that health promotion interventions addressed community needs and were designed using community resources and the wisdom of health practitioners that have been immersed in the local health system.So What?The study demonstrated the usefulness of vignettes in presenting data to lay people and how the rapid realist review approach is a practical tool for policy‐makers to ensure that program plans designed by the communities and health practitioners are evidence‐based without sacrificing the timeliness of implementation.
Denosumab Treatment Does Not Halt Progression of Bone Lesions in Multicentric Carpotarsal Osteolysis Syndrome
Authors: Lerman Melissa A. , Francavilla Michael , Waqar‐Cowles Lindsay , Levine Michael A. 
Published: February 2023

ABSTRACTHere we report the use of denosumab, a monoclonal antibody against receptor activator of nuclear factor κB ligand (RANKL), as monotherapy for multicentric carpotarsal osteolysis syndrome (MCTO) in an 11.5‐year‐old male with a heterozygous missense mutation in MAFB (c.206C>T; p.Ser69Leu). We treated the subject with 0.5 mg/kg denosumab every 60–90 days for 47 months and monitored bone and mineral metabolism, kidney function, joint range of motion (ROM), and bone and joint morphology. Serum markers of bone turnover reduced rapidly, bone density increased, and renal function remained normal. Nevertheless, MCTO‐related osteolysis and joint immobility progressed during denosumab treatment. Symptomatic hypercalcemia and protracted hypercalciuria occurred during weaning and after discontinuation of denosumab and required treatment with zoledronate. When expressed in vitro, the c.206C>T; p.Ser69Leu variant had increased protein stability and produced greater transactivation of a luciferase reporter under the control of the PTH gene promoter than did wild‐type MafB. Based on our experience and that of others, denosumab does not appear to be efficacious for MCTO and carries a high risk of rebound hypercalcemia and/or hypercalciuria after drug discontinuation. © 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
Identification of key events and regulatory networks in the formation process of primordial germ cell based on proteomics
Authors: Zuo Qisheng , Gong Wei , Yao Zeling , Xia Qian , Zhang Yani , Li Bichun 
Published: February 2023

AbstractCurrently, studies have analyzed the formation mechanism of primordial germ cell (PGC) at the transcriptional level, but few at the protein level, which made the mechanism study of PGC formation not systematic. Here, we screened differential expression proteins (DEPs) regulated PGC formation by label‐free proteomics with a novel sampling strategy of embryonic stem cells and PGC. Analysis of DEPs showed that multiple key events were involved, such as the transition from glycolysis to oxidative phosphorylation, activation of autophagy, low DNA methylation ensured the normal formation of PGC, beyond that, protein ubiquitination also played an important role in PGC formation. Importantly, the progression of such events was attributed to the inconsistency between transcription and translation. Interestingly, MAPK, PPAR, Wnt, and JAK signaling pathways not only interact with each other but also interact with different events to participate in the formation of PGC, which formed the PGC regulatory network. According to the regulatory network, the efficiency of PGC formation in induction system can be significantly improved. In conclusion, our results indicate that chicken PGC formation is a complex process involving multiple events and signals, which provide technical support for the specific application in PGC research.
Inter‐domain role transitions and work‐family life balance: The mediating effect of integration and segmentation preferences
Authors: Avolio Beatrice , Charles Vincent , Bautista Martha Liliana Albán 
Published: February 2023

AbstractDespite growing research on boundary management through role transitions, there is still a lack of understanding of the strategies individuals use to achieve work‐family life balance, and there is little research on the relationship between role transitions and work‐family life balance. This article aims to determine the extent to which inter‐domain role transitions affect work‐family life balance using segmentation and integration preferences as mediating variables. To achieve this objective, we conducted an empirical study in which data were collected from a sample of 311 executives (directors) from Ecuadorian higher education institutions. Using structural equation modeling, the direction and strength of the proposed relationships were determined. Findings show that family domain integration preference and family domain segmentation preference mediate the relationship between family‐to‐work role transitions and work‐family life balance. On the other hand, work domain segmentation preference and work domain integration preference were found to have no mediating effect between work‐to‐family role transitions and work‐family life balance. The findings have practical implications for managing work and family life boundaries. This research contributes to a better understanding of the mediating effect played by segmentation and integration preferences between inter‐domain role transitions and work‐family life balance from an individual perspective.
Simultaneous determination of 10 first‐generation histamine h1 receptor blockers in feeds by ultra‐high‐performance liquid chromatography triple quadrupole ion trap hybrid mass spectrometer
Authors: Decheng Suo , Xia Fan , Zhiming Xiao , Yang Li , Shi Wang 
Published: February 2023

A method for simultaneous determination of 10 first‐generation histamine H1 receptor blockers in feeds by ultra‐high‐performance liquid chromatography triple quadrupole mass spectrometry combined with solid phase extraction. Instrument conditions, extraction solvents, and purification methods have been optimized. Under the optimum conditions, these analytes were separated effectively at 6 min. These feeds have been extracted by acid acetonitrile and purified by mixed cation exchange solid‐phase extraction. The performance of this method meets the requirements of veterinary residue detection in feeds in China. It is appropriate for the confirmatory monitoring and quantitative analysis of 105 feed samples, five kinds of histamine H1 receptor blockers have been detected in 10 samples.
Adjuvant Radiation and Survival Following Surgical Resection of Sinonasal Adenocarcinoma
Authors: Vedula Sudeepti , Kheir Lena , Hu Patrick , Patel Aman M. , Roden Dylan F. , Park Richard C. 
Published: February 2023

ObjectivesThis study aims to investigate the utility of adjuvant radiation in patients who undergo surgical resection for the management of node‐negative sinonasal adenocarcinoma (SNAC).Study DesignRetrospective database review.MethodsThe 2004–2016 National Cancer Data Base (NCDB) was used to extract patients with surgically resected node‐negative SNAC. Kaplan–Meier survival analysis and Cox‐Proportional Hazards Modelling were used to analyze the impact of adjuvant radiation on overall survival (OS) following surgery.Results349 patients with SNAC underwent surgical resection. Of these patients, 154 (44.1%) received adjuvant radiotherapy (RT). Although there was no significant difference in race, age, or sex of those receiving RT, those receiving RT have more advanced diseases and are more likely to have positive margins. Kaplan Meier analysis showed no significant difference in 5‐year OS in patient who received adjuvant RT in comparison to those who underwent surgical resection alone (65.7% vs. 72.6%, respectively; p = 0.378). In addition, when looking at only patients with positive margins, 5‐year OS still did not have a significant difference (73.8% vs. 61.6%, respectively; p = 0.101). Only patients with clinical AJCC T4 showed a statistically significant survival benefit with adjuvant RT (56.9% vs. 29.9%, respectively; p = 0.009).ConclusionsAdjuvant RT does not appear to provide a significant survival benefit in patients with resected SNAC, with the exception of those with clinically AJCC T4 disease.Level of Evidence4 Laryngoscope, 133:2603–2612, 2023
Optical and Microwave Metrology at the 10−18 Level with an Er/Yb:glass Frequency Comb
Authors: Nardelli Nicholas V. , Leopardi Holly , Schibli Thomas R. , Fortier Tara M. 
Published: February 2023

AbstractOptical frequency combs are essential tools for precision metrology experiments ranging in application from remote spectroscopic sensing of trace gases to the characterization and comparison of optical atomic clocks for precision time‐keeping and searches for physics beyond the standard model. Presented here is a description of the architecture and a full characterization of a telecom‐band, self‐modelocking frequency comb based on a free‐space laser with an Er/Yb co‐doped glass gain medium. The laser provides a robust and cost‐effective alternative to Er:fibre laser based frequency combs, while offering stability and noise performance similar to Ti:sapphire laser systems. Finally, the utility of the Er/Yb:glass frequency comb is demonstrated in high‐stability frequency synthesis using two ultra‐stable optical references at 1157 nm and 1070 nm and in low‐noise photonic microwave generation by dividing these references to the microwave domain.
Uncertainty Qualification for Metasurface Design with Amendatory Bayesian Network
Authors: Zhang Jie , Qian Chao , Chen Jieting , Wu Bei , Chen Hongsheng 
Published: February 2023

AbstractHaving a prophetic ability to evaluate the uncertainty of deep learning is important to enable the critical reception of the output result. This is especially pronounced in the emerging domain of intelligent metasurfaces, due to the ubiquitous uncertainties from realistic fabrication and network modeling. Despite the great advancements that have mutated the design and working modality of metasurfaces, this enticing ability remains elusive. Here, a new paradigm to quantify the uncertainty in metasurface design is proposed by generalizing the Bayesian neural network. The uncertainty generally originates from the network model part and data part, the latter of which is imitated by the topologically‐distorted encoding method. The conventional Bayesian neural network is revised by embedding physical‐inspired elements to make it exclusive for metasurface design case. Taking a microwave metasurface as an example, such an approach is benchmarked by simultaneously yielding predicted results and specific uncertainty and also providing experimental reliability for different metasurface manufacturers. This work ushers in a fathomable tool to help users make better decisions for deep learning output, meriting other research domains of optics and materials science.
Evaluation of a two‐dimensional Moire‐free antiscatter grid for cone‐beam computed tomography
Authors: Kim Jongkuk , Kang Yoonseok , Hwang Taesoon , Park Myungkyu , Chung Woohyun 
Published: February 2023

AbstractBackgroundScatter radiation is a traditional problem in cone‐beam computed tomography (CBCT). Accordingly, numerous methods have been researched for scatter reduction in terms of software‐ or hardware‐based solutions. The concept of a two‐dimensional antiscatter grid (2D‐ASG) has been shown to provide a solution to the scatter reduction in CBCT. However, the use of an ASG makes it challenging to use in clinical CBCT systems because it causes Moire artifacts of the image.PurposeWe have developed a Moire‐free 2D‐ASG that was designed to solve the Moire artifact and the scatter radiation problems. We provide the experimental results pertaining to the image quality measurements from the evaluation of the 2D‐ASG compared with those obtained from a one‐dimensional antiscatter grid (1D‐ASG) and no antiscatter grid (No‐ASG) to demonstrate the quantitative extent of the improvements.MethodsThe 2D‐ASG, fabricated based on a sawing process with a graphite body, was prepared to evaluate image quality improvements. Projection images for Pro‐CT MK II phantom were acquired using the CBCT testbed of sample rotation type and reconstructed by Feldkamp–Davis–Kress (FDK) algorithm without any filters. We measured the contrast‐to‐noise ratio (CNR) and uniformity index for the cupping artifacts of the 2D‐ASG, 1D‐ASG, and No‐ASG cases.Results2D‐ASG considerably reduced the cupping artifacts owing to the scatter reduction compared with the 1D‐ASG and No‐ASG cases. The cupping artifacts were reduced by 85% in the 2D‐ASG compared with No‐ASG, while the cupping artifacts were reduced by 63% in 1D‐ASG compared with No‐ASG. The 2D‐ASG also yielded a CNR improvement. The average CNR improvements for eight insert materials were 47% in the 2D‐ASG compared with No‐ASG, while the CNR was improved by 36% in the 1D‐ASG compared with No‐ASG.ConclusionsWe demonstrated that the Moire‐free 2D‐ASG improved the image quality by removing scatter radiation in CBCT compared with 1D‐ASG and No‐ASG. We believe that the Moire‐free 2D‐ASG can become one of the effective ways to solve the scatter radiation problem in CBCT images because it provides usability and has the potential to have synergistic effects on other methods, such as bow‐tie filter and scatter correction.
Т1 mapping of rat lungs in 19F MRI using octafluorocyclobutane
Authors: Pavlova Olga S. , Gulyaev Mikhail V. , Gervits Lev L. , Hurshkainen Anna A. , Nikulin Anton V. , Puchnin Viktor M. , Teploukhova Ekaterina D. , Kuropatkina Tatyana A. , Anisimov Nikolay V. , Medvedeva Nataliya A. , Pirogov Yury A. 
Published: February 2023

PurposeTo demonstrate the feasibility of using octafluorocyclobutane (OFCB, c‐C4F8) for T1 mapping of lungs in 19F MRI.MethodsThe study was performed at 7 T in three healthy rats and three rats with pulmonary hypertension. To increase the sensitivity of 19F MRI, a bent‐shaped RF coil with periodic metal strips structure was used. The double flip angle method was used to calculate normalized transmitting RF field (B1n+) maps and for correcting T1 maps built with the variable flip angle (VFA) method. The ultrashort TE pulse sequence was applied for acquiring MR images throughout the study.ResultsThe dependencies of OFCB relaxation times on its partial pressure in mixtures with oxygen, air, helium, and argon were obtained. T1 of OFCB linearly depended on its partial pressure with the slope of about 0.35 ms/kPa in the case of free diffusion. RF field inhomogeneity leads to distortion of T1 maps built with the VFA method, and therefore to high standard deviation of T1 in these maps. To improve the accuracy of the T1 maps, the B1n+ maps were applied for VFA correction. This contributed to a 2–3‐fold decrease in the SD of T1 values in the corresponding maps compared with T1 maps calculated without the correction. Three‐dimensional T1 maps were obtained, and the mean T1 in healthy rat lungs was 35 ± 10 ms, and in rat lungs with pulmonary hypertension – 41 ± 9 ms.ConclusionOFCB has a spin‐rotational relaxation mechanism and can be used for 19F T1 mapping of lungs. The calculated OFCB maps captured ventilation defects induced by edema.
Jumble judging: Cognitive and affective outcomes of intercollegiate collaboration at a soil judging competition
Authors: Young Rebecca A. , Turk Judith K. , Jelinski Nicolas A. , Anderson Amber D. , Clark Kerry M. , Dere Ashlee , Moorberg Colby J. , Osterloh Kristopher , Presley DeAnn 
Published: February 2023

AbstractStudent–student interactions are influential parts of field experiences. While competitive judging events are a fun way to engage students in field‐based learning, the focus on competition leads to an atmosphere that discourages collaboration between students. The objective of this study was to evaluate the cognitive and affective learning outcomes resulting from intercollegiate collaboration at a soil judging competition. Teams with students from two to three different universities were assigned and referred to as jumble judging teams. Jumble judging was held for the first time in the 2021 Region 5 Collegiate Soil Judging Contest. Learning outcomes were assessed using a pre‐ and postsurvey, as well as group and individual reflections completed in the field. Student responses were generally positive, with 70% of students expressing agreement or strong agreement that they would like jumble judging to be included in future contests, 54% citing jumble judging as one of the best parts of the contest, and 93% identifying learning outcomes or describing an affective learning experience resulting from jumble judging. Evidence of both cognitive and affective learning were identified through student surveys and reflections. Overall, the event created a collaborative and collegial atmosphere and increased interaction between students from different universities, while maintaining the competitive nature of the event that motivates many students to get involved with judging teams.
Overfat cutoffs and the optimal combination of body fat indices for detecting cardiometabolic risk among school‐aged children
Authors: Dong Hongbo , Cheng Hong , Liu Junting , Yan Yinkun , Zhao Xiaoyuan , Shan Xinying , Huang Guimin , Mi Jie ,   the China Child and Adolescent Cardiovascular Health (CCACH) collaboration members
Published: February 2023

AbstractObjectiveThis study aimed to develop cutoffs and the optimal combination for body fat indices for screening cardiometabolic risk (CMR) among the pediatric population.MethodsThis cross‐sectional study consisted of 8710 (50.3% boys) Chinese children aged 6 to 18 years. Body fat indices, including fat mass index (FMI), body fat percentage, trunk to leg fat ratio (TLR), and android to gynoid fat ratio, were derived from dual‐energy x‐ray absorptiometry scans. The area under the receiver operating characteristic curve was used to determine the best combination and optimal cutoffs of body fat indices to identify CMR.ResultsCompared with anthropometry‐based obesity measures, i.e., BMI and waist circumference, the FMI + TLR combination presented statistically higher area under the receiver operating characteristic curve values for discriminating CMR and its clustering. The optimal overfat cutoffs of FMI and TLR were respectively determined at the 75th percentile in boys and at the 80th percentile of FMI and the 75th percentile of TLR in girls. Moreover, simplified thresholds derived from age‐group‐merged cutoffs showed similar performance as optimal cutoffs in detecting CMR.ConclusionsBoth the optimal and simplified overfat cutoffs were provided for the Chinese pediatric population. The use of FMI and TLR together allows for adequate screening of CMR and its clustering.
Revealing the Nanoarchitectonics of Amyloid β‐Aggregation on Two‐Dimensional Biomimetic Membranes by Surface‐Enhanced Infrared Absorption Spectroscopy
Authors: Zhu Manyu , Zeng Li , Li Zihao , Wang Chen , Wu Lie , Jiang Xiue 
Published: February 2023

AbstractThe in vivo folding of amyloid β (Aβ) is influenced by many factors among which biomembrane interfaces play an important role. Here, using surface‐enhanced infrared absorption (SEIRA) spectroscopy and atomic force microscopy (AFM), the adsorption, structure, and morphology of Aβ42 aggregating on different two‐dimensional interfaces were investigated. Results show that interfaces facilitate the aggregation of Aβ42 and are conducive to the formation of homogeneous aggregates, while the aggregates vary on different interfaces. On hydrophobic interfaces, strong hydrophobic interactions with the C‐terminus of Aβ42 result in the formation of small oligomers with a small proportion of the β‐sheet structure. On hydrophilic interfaces, hydrogen‐bonding interactions and electrostatic interactions promote the formation of large aggregate particles with β‐sheet structure. The hydration repulsion plays an important role in the interaction of Aβ42 with interfaces. These findings help to understand the nature of Aβ42 adsorption and aggregation on the biomembrane interface and the origin of heterogeneity and polymorphism of Aβ42 aggregates.