bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relation between religious attitude, psychological resilience and hope in female heads of households in Sirjan, Iran
Authors: Sadeghi Reza , Abolghaseminejad parniya , Borhaninejad Vahidreza , Amir Mohammad Moqaddasi , Zeidabadi Batool 
Published: July 2023

Abstract
Background
Female heads of households struggle with many problems and may encounter a lot of psychological pressure. Religious attitude may alleviate psychological pressures, and improve resilience. This study aimed to determine the relation between religious attitude, psychological resilience and hope in female heads of households in Sirjan in 2021.
Methods
This descriptive-analytical study used convenience sampling to enroll 400 eligible female heads of households covered by the Imam Khomeini relief committee in Sirjan in 2021. The Golriz-Barahani religious attitude questionnaire, the Connor-Davidson resilience scale, and the Snyder’ hope scale were used to collect information. Data were analyzed using SPSS 26, and descriptive statistics and Spearman's correlation coefficients were reported.
Results
The mean age of the participants was 43.22 ± 9.78 years. The mean scores of religious attitude, resilience, and hope were 66.03 ± 7.57 (from 100), 75.74 ± 8.93 (from 100), and 32.22 ± 3.50 (from 60), respectively. The results showed a significant positive relation between religious attitude and psychological resilience (P < 0.001) and between religious attitude and hope (P < 0.001).
Conclusions
Increasing religious attitude may help improve resilience and hope among female heads of households.
Hepatic ketogenesis regulates lipid homeostasis via ACSL1-mediated fatty acid partitioning
Authors: Ramakrishnan Sadeesh , Mooli Raja Gopal Reddy , Han Yerin , Fiorenza Ericka , Kumar Suchita , Bello Fiona , Nallanagulagari Anoop , Karra Shreya , Teng Lihong , Jurczak Michael 
Published: July 2023

Abstract

Liver-derived ketone bodies play a crucial role in fasting energy homeostasis by fueling the brain and peripheral tissues. Ketogenesis also acts as a conduit to remove excess acetyl-CoA generated from fatty acid oxidation and protects against diet-induced hepatic steatosis. Surprisingly, no study has examined the role of ketogenesis in fasting-associated hepatocellular lipid metabolism. Ketogenesis is driven by the rate-limiting mitochondrial enzyme 3-hydroxymethylglutaryl CoA synthase (HMGCS2) abundantly expressed in the liver. Here, we show that ketogenic insufficiency via disruption of hepatic HMGCS2 exacerbates liver steatosis in fasted chow and high-fat-fed mice. We found that the hepatic steatosis is driven by increased fatty acid partitioning to the endoplasmic reticulum (ER) for re-esterification via acyl-CoA synthetase long-chain family member 1 (ACSL1). Mechanistically, acetyl-CoA accumulation from impaired hepatic ketogenesis is responsible for the elevated translocation of ACSL1 to the ER. Moreover, we show increased ER-localized ACSL1 and re-esterification of lipids in human NASH displaying impaired hepatic ketogenesis. Finally, we show that L-carnitine, which buffers excess acetyl-CoA, decreases the ER-associated ACSL1 and alleviates hepatic steatosis. Thus, ketogenesis via controlling hepatocellular acetyl-CoA homeostasis regulates lipid partitioning and protects against hepatic steatosis.
Knowledge and Associated Factors towards Early Management of Acute Myocardial Infarctions among Nurses Working in the Adult Emergency Department of Selected Public Hospitals in Addis Ababa, Ethiopia
Authors: Kebede Roba , Kefyalew Merahi , Michael Mebrat , Kebede Kumela 
Published: July 2023

Abstract
Background
Acute myocardial infarction is a life-threatening condition and the leading cause of death that influences the individual's physical, psychological, and social dimensions. The increasing burden of myocardial infarction remains a low priority for public health in many countries. So, it is essential to determine the nurse’s knowledge of early management of myocardial infarction for life-threatening. Therefore, this study aimed to assess the knowledge and associated factors toward early management of acute myocardial infarction among nurses working in adult emergency rooms at selected public hospitals in Addis Ababa, Ethiopia. 2022
Method
An institution-based cross-sectional study design was conducted with 168 nurses working in adult emergency at selected public service hospitals in Addis Ababa, Ethiopia. The data were collected from April 15 to May 15, 2022 by self-administered questionnaire. The data were analyzed by using SPSS version 26 software.
Result
A total of 168 participants were included in the study, out of which 74(44%) participants had good knowledge of early management of acute myocardial infarction. In multivariable logistic regression analysis showed BSc degree (AOR = 0.06 95%CI (0.007–0.528)), Diploma nurses (AOR = 0.05 95%CI (0.004–0.48)), management guideline of acute myocardial infarction in a unit (AOR = 2.24 95%CI (1.02–4.9)), and training toward early management of acute myocardial infarction (AOR = 4.03 95%CI 1.68–9.69) were the factors significantly associated with the level of ED nurses knowledge towards early management of AMI.
Conclusion and Recommendation:
This study result indicates participants had inadequate knowledge of early management of acute myocardial infarction among nurses working in an adult emergency. Generally, I recommend that the upgrading education level the program must give for ED nurses, training programs should be provided for ED nurses on early AMI management, and AMI management guidelines/standard tools should be designed to improve ED nurses' knowledge.
C α −ruled surfaces respect to direction curve in fractional differential geometry
Authors: Has Aykut , Yılmaz Beyhan , Ayvacı Kebire Hilal 
Published: July 2023

Abstract
Conformable fractional calculus is a relatively new branch of mathematics that seeks to extend traditional calculus to include non-integer order derivatives and integrals. This new form of calculus allows for a more precise description of physical phenomena, such as those related to fractal geometry and chaos theory. It also offers new tools for solving problems in physics, engineering, finance, and other areas. By using conformable fractional calculus, researchers can gain insight into the behavior of systems that would otherwise be difficult or impossible to analyze. In this article, we will discuss the fundamentals of conformable fractional calculus and its applications in various fields. For this purpose ruled surfaces are studied with conformable fractional calculus. The ruled surface is rearranged concerning the conformable surface definition and geometric properties are investigated.
MSC Classification: 53A04 , 53A05 , 26A33
Folate-mediated Transport of Nanoparticles across the Placenta
Authors: Kalashnikova Irina , Patrikeeva Svetlana , Nanovskaya Tatiana N. , Andreev Yaroslav A. , Ahmed Mahmoud S. , Rytting Erik 
Published: July 2023

Background:
In this study, a prototype of a targeted nanocarrier for drug delivery for prenatal
therapy of the developing fetus was developed and examined in vitro and ex vivo. The folate
transport mechanism in the human placenta was utilized as a possible pathway for the transplacental delivery
of targeted nanoparticles.

Methods:
Several types of folic acid-decorated polymeric nanoparticles were synthesized and characterized.
During transport studies of targeted and non-targeted fluorescent nanoparticles across the placental
barrier, the apparent permeability values, uptake, transfer indices, and distribution in placental tissue
were determined.

Results:
The nanoparticles had no effect on BeWo b30 cell viability. In vitro, studies showed significantly
higher apparent permeability of the targeted nanoparticles across the cell monolayers as compared
to the nontargeted nanoparticles (Pe = 5.92 ± 1.44 ×10-6 cm/s for PLGA-PEG-FA vs. 1.26 ± 0.31
×10-6 cm/s for PLGA-PEG, P < 0.05), and the transport of the targeted nanoparticles was significantly
inhibited by excess folate. Ex vivo placental perfusion showed significantly greater accumulation of the
targeted nanoparticles in the placental tissue (4.31 ± 0.91%/g for PLGA-PEG-FA vs. 2.07 ± 0.26%/g for
PLGA-PEG).

Conclusion:
The data obtained suggested different mechanisms for the uptake and transplacental transfer
of targeted versus nontargeted nanoparticles. This targeted nanoformulation may be a promising
strategy for fetal drug therapy.
Emotional Intelligence and Academic Achievement Among Management and Science University’s (MSU) School of Education and Social Sciences (SESS) students
Authors: Afandi Nur Sabrina , Abu Bakar Abu Yazid 
Published: July 2023

This study aims to look at the existing level of emotional intelligence among Management and Science University’s (MSU) School of Education and Social Sciences (SESS) students. It will also look at the relationship between intrapersonal and interpersonal level among SESS students. The sample is 100 students that divide by 50 males and 50 females. In this research, it used a survey tool which Emotional Competencies Inventories (ECI). In this research it used inventory with 40 items in it. It is divided to two parts, intrapersonal and interpersonal abilities. First is to recognize emotions categories of self. Second is emotional self-management and lastly personal motivation. Interpersonal part is consists of two categories, which is the ability to recognize others feelings and the ability to handle relationships effectively. This researcher analyzes the data using the Statistical Package for the Social Science (SPSS) version 17.0. The reliability for this instrument (Emotional Intelligent Inventory) is .791. The data was process by using the descriptive statistics of the mean score and the standard deviation. Pearson correlation coefficient is used to measure the relationship between the construct of intrapersonal and interpersonal relationships among the students. The results showed that each of the questions and objectives of the study have been answered. The results of the study also illustrate the level of emotional intelligence among SESS students are at moderate level. This study also discusses the results of the study, future research recommendations and limitations of the study
Tepung Umbi Gadung (Dioscorea hispida Dennst) Sebagai Alternatif Media Pengganti Media PDA (Potato Dextrose Agar)
Authors: Halimah Nur , Apriani Ike , Sunarti Riri Novita 
Published: July 2023

Fungus belong to eukaryotic prosthetic organisms that are chemohypertrophic. When studying the properties of fungus, a material is needed as a nutritional source to grow or isolate fungus known as the media. The most commonly used media for fungal culture is instant PDA media. The relatively high price of instant PDA media is a common problem. That's why we need alternative media that are more economical. The aim of this research is to test whether the gadung tuber flour media can be used as an alternative to PDA. Method used in this study is the experimental method and design used, fully randomized design with 6 treatments and 4 replicates. Concentrations of gadung tuber flour used were 5%, 10%, 15%, 20% and 25%. The data obtained was analyzed with Annova with a confidence level of 95%. The results showed that the grading tuber meal alternative media had a significant effect on the growth of Candida albicans. Fungus can grow in alternative media at a concentration of 5% to 25% with the highest number of colonies at a concentration of 25%, namely 155.3 in 100 µl.AbstrakJamur termasuk organisme prostetik eukariotik yang bersifat kemohipertrofik. Dalam mempelajari sifat-sifat jamur diperlukan suatu bahan sebagai sumber nutrisi untuk menumbuhkan atau mengisolasi jamur yang dikenal dengan media. Media yang paling umum digunakan untuk kultur jamur adalah media PDA instan. Harga media PDA instan yang relatif mahal merupakan masalah yang umum. Untuk itu diperlukan media alternatif yang lebih ekonomis. Penelitian ini bertujuan untuk menguji apakah media tepung umbi gadung dapat digunakan sebagai alternatif pengganti PDA. Metode yang digunakan dalam penelitian ini adalah metode eksperimen dan desain yang digunakan, Rancangan Acak Lengkap dengan 6 perlakuan dan 4 ulangan. Konsentrasi tepung umbi gadung yang digunakan adalah 5%, 10%, 15%, 20% dan 25%. Data yang diperoleh dianalisis dengan Annova dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa grading media alternatif tepung umbi berpengaruh nyata terhadap pertumbuhan Candida albicans. Jamur dapat tumbuh pada media alternatif pada konsentrasi 5% sampai 25% dengan jumlah koloni tertinggi pada konsentrasi 25% yaitu 155,3 dalam 100 µl
The Chesapeake and Ohio (C&O) Canal’s Role in Developing the District of Columbia’s Ports
Authors: Laurie Trevor W. 
Published: July 2023

While the how and why of the Chesapeake and Ohio (C&O) Canal’s birth are important, and it is with much thanks that students of inland waterways (few are we in number) are able to access this accumulated knowledge, it is somewhat shocking that the major role this canal played in developing the Potomac River valley and, most importantly, the country’s capital region, is overlooked. This article will address the pivotal role the C&O Canal played in forming and developing the two main ports that serviced the greater District of Columbia area (encompassing northern Virginia), and, to a lesser extent, the middle Atlantic region.
Bien que le comment et le pourquoi des débuts du canal Chesapeake et Ohio (C&O) soient importants et que les amateurs des voies navigables intérieures (peu nombreux sommes-nous) soient très reconnaissants de pouvoir accéder aux connaissances acquises, il est étonnant que le rôle majeur qu’ait joué ce canal dans le développement de la vallée de la rivière Potomac et, plus important encore, de la région de la capitale nationale des États-Unis ait été laissé de côté. Cet article traite du rôle central du canal C&O dans la formation et le développement des deux principaux ports qui desservaient la grande région du district de Columbia (comprenant le nord de la Virginie) et, dans une moindre mesure, la région de l’Atlantique-Centre.
Barreras, retos y recomendaciones en la formación académica de los ingenieros civiles en Colombia
Authors: Salinas Guayacundo Daniel Ricardo 
Published: July 2023

Los ingenieros civiles diseñan construyen y mantienen la infraestructura de la sociedad moderna. Su formación académica y desempeño competente y ético debe ser considerado como prioritario para cualquier país. Desde una metodología mixta apoyada en aspectos cualitativos y datos cuantitativos, en el presente artículo de reflexión, se describen algunas barreras y retos presentes en la formación académica y ejercicio profesional de los ingenieros civiles en Colombia. A pesar de que en las últimas décadas, se ha avanzado en los procesos de Acreditación de Alta Calidad de las universidades y programas académicos en Colombia, se ha identificado que todavía hay mucho camino por recorrer. Aproximadamente, una de cada tres universidades y programas académicos de ingeniería civil ha recibido Acreditación de Alta Calidad por parte del Consejo Nacional de Acreditación de Colombia. Además, a pesar de que los profesores de ingeniería civil deben estar a la vanguardia de formación profesional, se registran algunas atipicidades que demandan atención especial por parte del gobierno colombiano y las universidades. Finalmente, se presentan una serie de recomendaciones enfocadas a mejorar la calidad de la educación en ingeniería civil en Colombia.
A Magnetic Field-Controlled Elastomer Composite Based on Porous Polydimethylsiloxane
Authors: Amirov A. A. , Kaminskiy A. S. , Arkhipova E. A. , Cherkasova N. A. , Tovpinets A. O. , Leucine V. N. , Pyatakov A. P. , Zhivulin V. E. , Rodionova V. V. 
Published: July 2023

Abstract
Magnetic elastomers are obtained using polydimethylsiloxane polymer filled with barium hexaferrite microparticles that have a homogeneous and porous microstructure. The microstructure and magnetic and mechanical properties of the synthesized samples are studied. The way of leaching the filler yields magnetic elastomers with a porosity of ~58%. It is shown that the porous microstructure reduces the Young’s modulus of the samples from 0.63 MPa (homogeneous) to 27 kPa (porous) and does not appreciably alter their magnetic properties.
PENGUATAN LITERASI DIGITAL MELALUI MATA KULIAH UMUM PENDIDIKAN PANCASILA UNTUK MENGANTISIPASI BERKEMBANGNYA BERITA HOAX
Authors: Suryaningsih Anis , Hidayah Yayuk , Pratomo Wachid 
Published: July 2023

Students are easily influenced by hoax news, so many students are easily provoked and become victims of hoax news (fraud). This study aims to determine the role of Pancasila education courses in improving digital literacy and Pancasila course strategies in anticipating the development of hoax news on social media. The research approach used in this study is qualitative and uses literature-based research methods. The data collection technique used is document study, and the data analysis used in this study is content analysis. The results showed that Pancasila Education plays a role in strengthening digital literacy by maximizing the competence of lecturers who teach Pancasila Education courses (professional, pedagogic, personality, and social). An effective strategy for strengthening digital literacy by building knowledge, skills, and character based on Pancasila This is done by utilizing digital technology and being encouraged to actively access information from digital technology, which then analyzes the information wisely. In addition, it is not easy to be provoked by fake news, which indirectly maintains the existence of Pancasila as the ideology of the Indonesian nation. Through this strategy, students can become good and smart digital citizens. AbstrakMahasiswa merupakan salah satu kalangan yang mudah terpengaruh dengan berita hoax, sehingga banyak mahasiswa yang mudah terprovokasi dan menjadi korban berita hoax (penipuan). Penelitian ini memiliki tujuan untuk mengetahui peran mata kuliah pendidikan Pancasila dalam meningkatkan literasi digital dan strategi mata kuliah Pancasila dalam mengantisipasi berkembangnya berita hoax di media sosial. Pendekatan penelitian yang digunakan dalam penelitian ini ialah kualitatif dan menggunakan metode penelitian kepustakaan. Teknik pengumpulan data yang digunakan adalah studi dokumen dan analisis data yang digunakan dalam penelitian ini ialah analisis konten. Hasil penelitian menunjukkan bahwa peran pendidikan Pancasila dalam penguatan literasi digital dengan memaksimalkan pemanfaatan kompetensi dosen yang mengampu mata kuliah Pendidikan Pancasila (profesional, pedagogik, kepribadian, dan sosial). Strategi yang efektif dalam penguatan literasi digital dengan membangun pengetahuan, keterampilan dan karakter berdasarkan Pancasila. Hal tersebut dilakukan dengan cara memanfaatkan teknologi digital dan didorong untuk aktif mengakses informasi dari teknologi digital yang kemudian menganalisis informasi tersebut dengan bijak. Selain itu, dengan tidak mudahnya terprovokasi dengan berita bohong pada dasarnya secara tidak langsung dapat menjaga eksistensi Pancasila sebagai ideologi bangsa Indonesia. Melalui strategi tersebut mahasiswa dapat menjadi warga digital yang baik dan cerdas.
The interactions between agonist-to-antagonist muscle strength performance and plantar pressure distribution, foot contact area, and impulse in novice ballet dancers
Authors: Arinli Yağmur , Umutlu Gökhan , Pehlevan Zekai 
Published: July 2023

BACKGROUND: Hip, trunk, knee, and ankle/foot muscles may lead to increased variability in the components of balance and plantar pressure distribution (PPD) analysis. However, the role of these muscle groups in the PPD of different ballet techniques in novice ballet dancers has not previously been studied. OBJECTIVE: Our objective was to examine whether balance and PPD vary among five different ballet techniques and correlate with the agonist-to-antagonist strength performance of trunk, knee, hip, and ankle muscles in adolescent ballet dancers. METHODS: The anthropometric parameters, muscle strength performance, balance, and PPD of sixty healthy female ballet dancers (age: 14.36 ± 2.18 y) were measured at 48-h intervals. RESULTS: The forefoot’s PPD was significantly greater than the midfoot and rearfoot for all techniques (p= 0.000). The percent plantar load of forefoot during développé à la seconde (side, front, back), passé, and penché was greater than midfoot (166.56%, 161.51%, 168.11%, 165.14%, 174.04%) and rearfoot (47.75%, 32.84%, 43.83%, 48.73%, 49.66) for all techniques, respectively. The forefoot’s PPD, impulse, and contact area during all techniques were significantly correlated with the trunk muscle strength ratio (p< 0.05). CONCLUSION: Ballet dancers with higher trunk muscle strength imbalance showed a greater percentage difference in pressure load between the left and right foot in the anterior and posterior directions, poor balance, aggravated trunk imbalance, increased PPD, contact area, and impulse in the forefoot during each technique.
Epidermal growth factor alters silica nanoparticle uptake and improves gold-nanoparticle-mediated gene silencing in A549 cells
Authors: Susnik Eva , Bazzoni Amelie , Taladriz-Blanco Patricia , Balog Sandor , Moreno-Echeverri Aura Maria , Glaubitz Christina , Brito Oliveira Beatriz , Ferreira Daniela , Viana Baptista Pedro , Petri-Fink Alke , Rothen-Rutishauser Barbara 
Published: July 2023

Introduction: Delivery of therapeutic nanoparticles (NPs) to cancer cells represents a promising approach for biomedical applications. A key challenge for nanotechnology translation from the bench to the bedside is the low amount of administered NPs dose that effectively enters target cells. To improve NPs delivery, several studies proposed NPs conjugation with ligands, which specifically deliver NPs to target cells via receptor binding. One such example is epidermal growth factor (EGF), a peptide involved in cell signaling pathways that control cell division by binding to epidermal growth factor receptor (EGFR). However, very few studies assessed the influence of EGF present in the cell environment, on the cellular uptake of NPs.Methods: We tested if the stimulation of EGFR-expressing lung carcinomacells A549 with EGF affects the uptake of 59 nm and 422 nm silica (SiO2) NPs. Additionally, we investigated whether the uptake enhancement can be achieved with gold NPs, suitable to downregulate the expression of cancer oncogene c-MYC.Results: Our findings show that EGF binding to its receptor results in receptor autophosphorylation and initiate signaling pathways, leading to enhanced endocytosis of 59 nm SiO2 NPs, but not 422 nm SiO2 NPs. Additionally, we demonstrated an enhanced gold (Au) NPs endocytosis and subsequently a higher downregulation of c-MYC.Discussion: These findings contribute to a better understanding of NPs uptake in the presence of EGF and that is a promising approach for improved NPs delivery.