bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward Holistic Digital Material Description During Press-Hardening
Authors: Wesselmecking Sebastian , Ackermann Marc , Blankart Charline , Wang Jing , Brasche Frederike , Plum Tobias , Qin Siyuan , Pütz Felix , Münstermann Sebastian , Broeckmann Christoph , Hirt Gerhard , Ulrich Krupp 
Published: July 2023

AbstractPress hardening of manganese-boron steels is one of the most widely used production processes for high-strength automotive components. The low residual formability of these parts is a decisive disadvantage. The low formability originates from a strong, but brittle martensitic microstructure transformed during quenching in the press-hardening tool. In contrast, medium manganese steels (MMnS) contain high fractions of ductile retained austenite improving press-hardened parts toward promising candidates for crash-relevant car body components. Disadvantages include a more complex alloy design, a highly sensitive production process, and more demanding requirements on the tool due to higher strength during press-hardening.A detailed description of the entire production process along the process chain including the material and the press-hardening tool is important for tailoring the properties. Combined information is required to enable a precise control of the production process and its influences on the final properties of the part. Maximum economic use of the material is achieved by digitally describing MMnS as well as the tool along the entire process chain (casting, forging, hot rolling, cold rolling, galvanizing and press hardening including Q&P). To link the process steps and to describe the changes of the material, a new material database structure (idCarl) was developed. All production parameters are recorded and processed as a digital material twin. Ultimately, deviations occurring during production process can be deduced from in-line data analysis and counteracted. These can then be counteracted by adapted process control and the product can be brought back into the required parameter field of properties. Clear identification of the component and the used material allows conclusions about steps responsible for errors in the production process that become apparent during use.
Digital Shadows: Infrastructuring the Internet of Production
Authors: van der Aalst Wil M. P. , Jarke Matthias , Koren István , Quix Christoph 
Published: July 2023

AbstractDigitization in the field of production is fragmented in very different domains, ranging from materials to production technology to process and business models. Each domain comes with specialized knowledge, often incorporated into mathematical models. This heterogeneity makes it hard to naively exploit advances in data-driven machine learning that could facilitate situation adaptation and experience transfer. Innovative combinations of model-driven and data-driven solutions must be invented but also made comparable and interoperable to avoid ending up in information silos. In future World Wide Labs (WWLs), experiences can be shared, aggregated, and used for innovation. WWLs will be complex, evolving socio-technical networks of interconnected devices, software, data stores, and humans as users and contributors of expert knowledge and feedback. Integrating a large number of research labs, engineering, and production sites requires a capable cross-domain Internet of Production (IoP) infrastructure. The IoP project claims Digital Shadows (DSs) to offer a shared conceptual foundation for infrastructuring the IoP. In engineering, DSs were introduced as the data provision link to Digital Twins, whereas in computer science, DSs generalize the well-established concept of database views. In this chapter, we elaborate on the roles of DSs in infrastructuring the IoP from three perspectives: analytic functionality, conceptual organization, and technical networking. As an example where an integrative DS-like approach is already highly successful, we showcase the approach and infrastructure of the process mining field.
Challenges for Participation and Empowerment. Six Youth Dialogue Projects in Comparative Perspective
Authors: Treimer Swantje , Lorenz Astrid 
Published: July 2023

AbstractYouth work aimed at empowering people to be active citizens is demanding in organisational and didactic terms, and because of diverse contexts and EU perceptions which have to be respected. This chapter compares the practical challenges encountered by organisers of six youth dialogue projects in post-socialist regions of the European Union funded by Erasmus+ in 2019. It identifies typical challenges, including varying attitudes toward the EU and EU citizenship, a low interest in politics, challenging living conditions, underdeveloped youth work opportunities in remote rural areas, the difficulties in reaching a target group, the unstable motivation of young people, a lack of prior knowledge, no systematic consideration of the youth dialogue results by decision-makers, the unclear long-term effects of the projects and problems with funding. It also discusses the findings in light of previous studies on youth work and European citizenship that did not specifically focus on our region of interest.
A Building Block of an Overall Strategy for Political Education: Decide on Europe
Authors: Tadzhetdinova Amaliia , Gutzer Grete 
Published: July 2023

AbstractThis chapter deals with the Erasmus+ funded project Decide on Europe and how it was established as a transnational project between the Czech Republic and Slovakia to teach and inform secondary school students about European policy and the possibilities to participate in youth initiatives. Furthermore, challenges and problems, such as being able to reach out to students from rural areas, but also success factors, for example being able to be involved in a well-known project, with more and more participants each time, are addressed to provide an informative overview regarding the project.
Even Successful Projects Must End? Lessons Learned from the Project The Best Is Yet to Come
Authors: Bockelmann Henrieke , Samstag Svenja 
Published: July 2023

AbstractThis chapter reports about the transnational youth project The Best is yet to Come and the processes and challenges the organisers faced when creating a voice for young people from rural areas. The project also aimed at preparing a “European Rural Youth Parliament”, which brings together young people from different European countries to discuss and exchange ideas on life in rural areas. It was funded within the EU’s Erasmus+ framework. The chapter presents the framework conditions for such a project, as well as the benefits of involving youth. The sustainability of such and similar projects is critically considered, with an additional focus on network building and administrative processes. The chapter reveals that even if young people are enthusiastic and interested in creating a common European youth voice in rural areas, the structures to support these ambitions might not be sufficient to involve them systematically and can be strengthened.
Perspectives for Digital Participation in Rural Areas: Evidence from German Regions
Authors: Stein Veronika , Pentzold Christian 
Published: July 2023

AbstractThe shortcomings of top-down policies for rural development underscore the importance of local potentials and the role of citizens who are perceived as taking a more active role in shaping the future of rural areas. The engagement of the local population is facilitated by digitally-supported forms of civic participation. These technological services, in particular, should reach younger target groups. This shift toward citizen-centred approaches in rural development is manifested on the EU level in programs like LEADER, as well as in country-specific or regional initiatives. In our contribution, we draw on three case studies from Germany in order to make suggestions for local actors on how to foster citizen participation in a ‘smart’ way.
EU Citizenship and the Young People in the Peripheral Areas of East Central Europe: Three Recommendations for Research on Citizenship
Authors: Karolewski Ireneusz Paweł 
Published: July 2023

AbstractEU citizenship is a specific case of citizenship, which transnationally expands nation-state citizenship by focusing on cross-border mobility and transnational participation rights. The chapter argues that the key issue with EU citizenship remains the equality of status, especially when it comes to young people in peripheral areas of East Central Europe. The chapter sketches some key issues of citizenship research including EU citizenship. It also problematizes them concerning peripheral (especially rural) areas and young citizens. Against this backdrop, it formulates three recommendations for the research on citizenship, specifically EU citizenship with regard to rural areas in East Central Europe. The recommendations focus on (1) the difference between urban and rural citizenship, (2) direct social rights, and (3) the EU citizenship as nested and enacted citizenship.
No Strong Sense of Belonging and the EU as a Security-Provider: How Young People in Rural Poland Perceive EU Citizenship
Authors: Stosik Jolanthe , Sekunda Tomasz 
Published: July 2023

AbstractThis chapter analyses how students in secondary and vocational schools in peripheral areas in Poland perceive the EU and EU citizenship. It shows that most students do not feel particularly connected to other EU citizens. However, a security-providing EU could create a certain basis for a sense of belonging, as for example through health services, the joint protection of the EU’s external borders in Poland or in providing a guaranteed workplace. Most of the students reported that the EU seems to be very distant while national issues are much more present in the media, and thus perceived as more important. Yet, the majority considered EU elections important and expressed a desire to learn more about the EU and the EP elections through a comprehensible information campaign enabling young people to understand what is at stake.
Low Attachment to an EU that Is Associated with Mobility. Students’ EU Perceptions in Two Romanian Peripheral Towns
Authors: Ferenczi Andreea , Micu Cornel 
Published: July 2023

AbstractIn Romania, the EU accession was overwhelmingly supported by the people but over time the support, although still high, started to dwindle. As a contribution to understand the opinions regarding the EU in Romanian society, this chapter reports the empirical findings of group discussions with students aged 16 and 17 in two Romanian small towns in peripheral areas. The two selected towns, Moreni in the southern part of Romania and Caransebeș in Transylvania, are rather different with regard to their general layout and history. Despite these differences, the students viewed the debated issues in broadly the same way. As the report reveals, they emphasised the lack of information regarding the EU and the rights associated with EU citizenship, and expressed interest in learning more about these topics. They didn’t fully relate to the European identity values and prioritised their national or local identity instead.
Pedagogical Experimentalism and the Principle of Verification. A Quest for Non-affirmative Educational Research
Authors: Su Hanno , Bellmann Johannes 
Published: July 2023

AbstractStarting from the ongoing debate over whether education should take a non-affirmative stance towards reality, we pose the question of whether adopting a non-affirmative theory of education necessarily calls for a non-affirmative concept of educational research. We argue that dominant paradigms of both qualitative and quantitative research on education, respectively, assume a specific affirmative stance, which not only leads them to ignore the productive freedom of the practice of education that they investigate but also reproduces a dichotomy between education and research instead of inscribing themselves in the project of verification of the principles that are at stake in education. We do so by revisiting, first, Benner’s early outline of Pedagogy as a practically experimenting science as an alternative to dominant research paradigms, second, Mollenhauer’s critical pedagogy and its attempt to conceptualize non-affirmative educational research, and, third, Rancière’s interventional empiricism with a particular focus on the concept of practical “verification.” In this vein, we aim to contribute to the contemporary concept of non-affirmative educational research, which allows for a more precise understanding of the ways in which such an approach is at the same time affirmative with respect to the principles which are “verified” in the practice of education.
On the Normativity of Data-Driven Curriculum Policy-Making: A Discursive and Non-affirmative Approach
Authors: Nordin Andreas 
Published: July 2023

AbstractThis paper raises a critical argument on the normativity of data-driven curriculum policy-making in shaping and reshaping education at all levels along an evaluative rationale. The critique evolves in two steps, the first step is deconstructive in character and draws on the work of Porter (Trust in numbers: The pursuit of objectivity in science and public life. Princeton University Press, Princeton, 1995) and research on data-driven education. The second step is reconstructive in character, making use of the non-affirmative theory in education (Benner, On affirmativity and non-affirmativity in the context of theories of education and Bildung. In M. Uljens (Ed.), Non-affirmative Theory of Education and Bildung. Springer, 2023; Uljens, Revista Tempos e Espaços em Educação 18(9): 121–132, 2016; Trans Curric Inquiry 15(2): 4–25, 2018; Uljens & Ylimaki, Nord J Stud Educ Policy 1, 30–43, 2015; Bridging educational leadership, curriculum theory and didaktik: Non-affirmative theory of education. Springer, Cham, 2017) to elaborate on a more reflexive position. The critical examination shows how competitiveness, objectivity, and distance operate as educational ideals within the discourse of data-driven curriculum policy-making, narrowing the educational imagination to what can be expressed in league tables and ranking lists and promoting easy answers to complex questions of what works. These ideals are challenged by non-affirmative theory, which proposes a more reflexive approach to curriculum policy-making, emphasising process rather than outcome and questions rather than answers as drivers of such processes.
Netzwerkanalyse
Authors: Jünger Jakob , Gärtner Chantal 
Published: July 2023

ZusammenfassungDieses Kapitel führt in die Methode der Netzwerkanalyse ein. Sie lernen Grundbegriffe und Kennwerte der Netzwerkanalyse kennen und erlernen Techniken zur Erhebung, Aufbereitung und Analyse von Netzwerkdaten.Im Online-Repositorium unter https://github.com/strohne/cm finden Sie begleitend zum Kapitel weitere Materialien, auf die wir im Text mit ☛ verweisen.
Programmierung
Authors: Jünger Jakob , Gärtner Chantal 
Published: July 2023

ZusammenfassungDieses Kapitel führt in die Programmierung mit R und Python ein. Sie erlernen die Grundlagen der beiden Programmiersprachen, um erste Erfahrungen mit der Datenaufbereitung und -analyse zu sammeln.Im Online-Repositorium unter https://github.com/strohne/cm finden Sie begleitend zum Kapitel weitere Materialien, auf die wir im Text mit ☛ verweisen.
Textanalyse
Authors: Jünger Jakob , Gärtner Chantal 
Published: July 2023

ZusammenfassungDieses Kapitel führt in die automatisierte Textanalyse ein. Sie lernen, wie man Wortfrequenzanalysen durchführt und Texte mithilfe von Diktionären analysiert. Zudem werden grundlegende Konzepte von automatisierten Inhaltsanalysen sowie von Natural Language Processing vorgestellt.Im Online-Repositorium unter https://github.com/strohne/cm finden Sie begleitend zum Kapitel weitere Materialien, auf die wir im Text mit ☛ verweisen.
Catalytic antibodies in arrhythmogenic cardiomyopathy patients cleave desmoglein 2 and N-cadherin and impair cardiomyocyte cohesion
Authors: Yeruva Sunil , Stangner Konstanze , Jungwirth Anna , Hiermaier Matthias , Shoykhet Maria , Kugelmann Daniela , Hertl Michael , Egami Shohei , Ishii Norito , Koga Hiroshi , Hashimoto Takashi , Weis Michael , Beckmann Britt-Maria , Biller Ruth , Schüttler Dominik , Kääb Stefan , Waschke Jens 
Published: July 2023

Abstract
Aims
Arrhythmogenic cardiomyopathy (AC) is a severe heart disease predisposing to ventricular arrhythmias and sudden cardiac death caused by mutations affecting intercalated disc (ICD) proteins and aggravated by physical exercise. Recently, autoantibodies targeting ICD proteins, including the desmosomal cadherin desmoglein 2 (DSG2), were reported in AC patients and were considered relevant for disease development and progression, particularly in patients without underlying pathogenic mutations. However, it is unclear at present whether these autoantibodies are pathogenic and by which mechanisms show specificity for DSG2 and thus can be used as a diagnostic tool.

Methods and Results
IgG fractions were purified from 15 AC patients and 4 healthy controls. Immunostainings dissociation assays, atomic force microscopy (AFM), Western blot analysis and Triton X-100 assays were performed utilizing human heart left ventricle tissue, HL-1 cells and murine cardiac slices. Immunostainings revealed that autoantibodies against ICD proteins are prevalent in AC and most autoantibody fractions have catalytic properties and cleave the ICD adhesion molecules DSG2 and N-cadherin, thereby reducing cadherin interactions as revealed by AFM. Furthermore, most of the AC-IgG fractions causing loss of cardiomyocyte cohesion activated p38MAPK, which is known to contribute to a loss of desmosomal adhesion in different cell types, including cardiomyocytes. In addition, p38MAPK inhibition rescued the loss of cardiomyocyte cohesion induced by AC-IgGs.

Conclusion
Our study demonstrates that catalytic autoantibodies play a pathogenic role by cleaving ICD cadherins and thereby reducing cardiomyocyte cohesion by a mechanism involving p38MAPK activation. Finally, we conclude that DSG2 cleavage by autoantibodies could be used as a diagnostic tool for AC.
Digital twins for the rapid startup of manufacturing processes: a case study in PVC tube extrusion
Authors: Bovo Enrico , Sorgato Marco , Lucchetta Giovanni 
Published: July 2023

AbstractIn this work, a soft sensor–based digital twin (DT) was developed to reduce the startup time in manufacturing plastic tubes and enable real-time product quality monitoring, i.e., the weight per unit length and the inner and outer diameters of the tube. An experimental campaign was conducted on a real tube extrusion line using three polyvinyl chloride (PVC) compounds and different process conditions, and machine learning regression algorithms were trained and tested to create the models of the extruder and the extrusion die the DT is based on. The characterization of the considered material, whose properties were given as input to the digital models, was carried out according to a procedure based only on the data collected by the production line. The DT was tested for the startup of the production of a single-layer tube and allowed to achieve the specified customer requirements (thickness and weight) in a few minutes. The proposed solution thus proved to be a valuable tool for reducing the setup time, thus increasing the efficiency of the process.
Rechtsmedizin im „forensischen Medienmarkt“
Authors: Ritz-Timme S. , Paganini C. , Duttge G. , Hansson N. , Turnsek A. , Fangerau H. 
Published: July 2023

ZusammenfassungDie „breite Öffentlichkeit“ zeigt ein großes Interesse an der Rechtsmedizin, die dadurch in den Fokus des Medienmarktes rückt. Zunehmend gewähren Rechtsmedizinerinnen und Rechtsmediziner auch Einblicke in die Realität des Faches, mittlerweile auch in selbst produzierten Beiträgen in den Social Media. Diese Entwicklung (die „Mediatisierung der deutschen Rechtsmedizin“) ist Gegenstand von Forschung anderer Disziplinen.Danach besitzt die Rechtsmedizin ein großes „mediales Kapital“, das sowohl aus dem Interesse der Öffentlichkeit an Einblicken in das Tätigkeitsfeld an sich wie auch an den bearbeiteten Fällen (True Crime) resultiert. Die Nutzung dieses Kapitals mit der öffentlichen „Vermarktung“ rechtsmedizinischer Inhalte und von Bildern Verstorbener wirft Fragen nach Grenzen des juristisch und ethisch Zulässigen auf.Rechtliche Fragen betreffen insbesondere die Zulässigkeit der Nutzung von im Rahmen einer Sachverständigentätigkeit erlangten Informationen oder Bildern für eine Präsentation in (Massen‑)Medien. Aus ethischer Sicht werden u. a. die kommerzielle Nutzbarmachung der Faszination von Gewalttaten, bei Einsatz von Bildern auch die Risiken einer emotionalen Überforderung des Publikums und eine „Objektwerdung“ Verstorbener kritisiert. Da der Erfolg eines Formates mit dem Grad effektheischender Präsentation steigt, resultiert die Gefahr einer schiefen Ebene weg von der Information zur Sensation. Eine primär sensationsgetriebene Präsentation rechtsmedizinischer Inhalte wird problematisch gesehen.Die Nutzung des medialen Kapitals der Rechtmedizin hat Implikationen für die Außenwahrnehmung des Faches. Deshalb sollte die Mediatisierung der Rechtsmedizin nicht nur von anderen Disziplinen beforscht und diskutiert werden, sondern Gegenstand eines Diskurses auch innerhalb des Faches sein.
Sudden cardiac death of a 16-year-old boy with Wolff-Parkinson-White syndrome and hypertrophic cardiomyopathy
Authors: Bohnert Simone , Heinsen Helmut , Preiß Ulrich , Bohnert Michael 
Published: July 2023

AbstractIn Europe, 350,000 people die suddenly and unexpectedly every year. The majority of sudden deaths are caused by cardiac alterations and known as sudden cardiac death (SCD). The interpretation of medicolegal findings is especially difficult in those SCDs where there is no morphological correlate and no antemortem electrocardiograms or relevant medical history are available. The Wolff-Parkinson-White (WPW) syndrome, in which an accessory electrical conduction pathway exists between the atrium and the ventricle in addition to the physiological conduction system, is mostly a benign disease of the heart, which may lead to cardiac arrhythmia. A 16-year-old boy with a known history of WPW syndrome since the second year of life had consumed alcohol before death and was found sitting on the toilet fully dressed. The autopsy performed on the deceased 3 days postmortem showed a marked mass increase of the heart with left ventricular concentric hypertrophy and macroscopic signs of cardiomyopathy. In the microscopic examination, the right and left ventricles and the atria were found to have a regular structure with normal vessels. Hematoxylin-eosin (HE) and elastica-van-Gieson (EvG) staining disclosed a thin accessory muscle bridge connecting the left atrium with the left ventricle as a possible morphological correlate of a fatal cardiac arrhythmia.