bluuebunny/crossref_metadata_2025_split huggingface dataset:
The identification of high-performing antibodies for Secreted frizzled-related protein 1 (sFRP-1) for use in Western Blot and immunoprecipitation
Authors: Ayoubi Riham , Southern Kathleen , Laflamme Carl ,   NeuroSGC/YCharOS collaborative group
Published: March 2023

Secreted frizzled-related protein 1 (sFRP-1) is a secreted protein, belonging to the secreted glycoprotein SFRP family. As a modulator of the Wnt/β-catenin signalling pathway, sFRP-1 has implications in human cancers and neurologic diseases. If the community had access to well-characterized anti-sFRP-1 antibodies, the reproducibility of sFRP-1 research would be enhanced. In this study, we characterized 11 sFRP-1 commercial antibodies for Western Blot and immunoprecipitation, using a standardized experimental protocol based on comparing read-outs in knockout cell lines and isogenic parental controls. We identified many well-performing antibodies and encourage readers to use this report as a guide to select the most appropriate antibody for their specific needs.
EXPLORING STOICISM IN LEADERSHIP: A Comparison with Emotional Intelligence in Undergraduate Leadership Students
Authors: Brown Amy M. C. , Sowcik Matthew , Stedman Nicole L. P. , Bunch James C. 
Published: March 2023

This study was the first to examine two related constructs within the context of leadership. Stoicism is an ancient philosophy offering practical advice for a virtuous and eudaemonic life. As a method to examine one’s emotional experiences (Sellars, 2006), leaders such as Roman Emperor Marcus Aurelius and Teddy Roosevelt (Aurelius, ca. 160 A.D., 2002) practiced Stoicism, yet mentions of it within the field of leadership research have been scant. Leadership academics contrast desirable emotional intelligence behaviors with Stoicism (Grewal & Salovey, 2005; Mayer et al., 2008). Regardless, these two constructs are both concerned with effectively managing emotions, practicing self-awareness, high levels of motivation, and sensitivity to the expression of emotion in others (Goleman, 2005; Pigliucci, 2017; Salzgeber, 2019).
Undergraduate students in a leadership minor (_N_ = 445) at a public university completed the Emotional and Social Competency Inventory - University and the Liverpool Stoicism Scale. Analysis included a description of assessment results, an examination or the relationship between variables and differences in participant’s scores based on race, gender, and age. Stoicism and emotional self-awareness showed a moderate, statistically significant negative correlation (_r_ = - 0.391, _p_ = .05). A low, statistically significant negative relationship was reported between stoicism and the relationship management competency of teamwork (p = .003, r = -.018), and a low statistically significant positive relationship between self-management competencies, adaptability (p = .043, r = .189) and emotional self-control (p = .039, r = .192). Student’s Stoicism scores were significantly correlated with gender (_t_(113) = 2.479; _p_ = .015, _d_ = .564).
The research findings provided baseline statistics for continued exploration of Stoicism within the context of leadership. Future research that better aligns with the original doctrines of the philosophy is recommended, particularly in the interest of leadership development.
A MULTI-DISCIPLINARY MULTI-DEGREE STUDY OF WORKFORCE AND LEADERSHIP COMPETENCIES WITHIN POSTSECONDARY ACCREDITING ORGANIZATIONS
Authors: Seemiller Corey , Rosch David M. 
Published: March 2023

In conducting a multi-disciplinary, multi-degree study of all 83 higher education accrediting organizations in the United States and the 605 academic programs associated with them, our goal was to uncover patterns in the presence of leadership and general workforce competencies identified within the stated learning outcomes employed by these accrediting organizations. Our findings suggest strong variability across categories of leadership competence related to workforce competencies, where skills related to reasoning and communication were emphasized much more heavily than others such as intrapersonal development. These findings emerged across all postsecondary degree levels, from pre-baccalaureate to graduate programs, raising important questions for the leadership development of post-secondary students. Keywords: outcomes assessment, student leadership, professional development, leadership education, workforce development, competencies.
While colleges and universities often make the case that preparing students for future career success is critical, studies that examine the empirical support for the assertion curiously lag behind the advanced rhetoric. This paper will showcase research findings based on an analysis of 36,327 learning outcomes addressed within all 83 higher education accrediting organizations in the United States, representing 605 distinct postsecondary academic programs. Our goal was to uncover any patterns of emphasis in particular workforce and leadership competencies embedded within those learning outcomes and examine the extent to which those competencies are represented similarly across postsecondary degree levels.
Predictive Analytics and Ship-Then-Shop Subscription
Authors: Choi W. Jason , Liu Qihong , Shin Jiwoong 
Published: March 2023

This paper studies an emerging subscription model called ship-then-shop. Leveraging its predictive analytics and artificial intelligence (AI) capability, the ship-then-shop firm curates and ships a product to the consumer, after which the consumer shops (i.e., evaluates product fit and makes a purchase decision). The consumer first pays the up-front ship-then-shop subscription fee prior to observing product fit and then pays the product price afterward if the consumer decides to purchase. We investigate how the firm balances the subscription fee and product price to maximize its profit when consumers can showroom. A key finding is the ship-then-shop firm’s nonmonotonic surplus extraction strategy with respect to its prediction capability. As prediction capability increases, the firm first switches from ex ante to ex post surplus extraction (by lowering fees and raising prices). However, if the prediction capability increases further, the firm reverts to ex ante surplus extraction (by raising fees and capping prices). We also find that the ship-then-shop model is most profitable when (i) the prediction capability is advanced, (ii) the search friction in the market is large, or (iii) the product match potential is large. Finally, we show that the marginal return of AI capability on the firm’s profit decreases in search friction but increases in product match potential. Taken together, we provide managerially relevant insights to help guide the implementation of the innovative subscription model. This paper was accepted by Dmitri Kuksov, marketing. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2023.4723 .
Occlusal splints: the role and fabrication of stabilization splints
Authors: Mehta Shamir B , Banerji Subir 
Published: March 2023

Occlusal splints are a useful adjunct in the management of temporomandibular disorders, bruxism and the protection of the natural or restored dentition. Along with a video to accompany the text, this article gives an overview of the role and fabrication of occlusal splints. Indications as well as the clinical and laboratory protocol required for the construction of a full-coverage, hard acrylic splint are covered, along with the current role of CAD/CAM. A video accompanies this article. CPD/Clinical Relevance: The ability to provide a full-coverage, hard acrylic splint will be useful in selected cases.
Acrylic dentures: fill the gap. Part 3: the most common acrylic denture cases
Authors: Heran Jasmeet , Leyssen Wouter , Walmsley AD 
Published: March 2023

Acrylic partial dentures often do not receive the same attention to detail when being planned compared to cobalt–chromium prostheses. However, if a system of design is followed when planning acrylic dentures, retention, stability and support of the prostheses can be improved, increasing patient satisfaction. The aim of the third part of this series is to demonstrate how the design principles can be put into practice using a series of examples of the most common partially dentate situations encountered at the Birmingham Dental Hospital. CPD/Clinical Relevance: Knowledge of the principles of denture design for mucosal-borne partial dentures as applied to cmmon saddle situations.
Extending the role of the dental professional in the management of non-melanoma skin cancer
Authors: Bradley Hannah , Carnegie David , Keys William 
Published: March 2023

Non-melanoma skin cancer is the most frequently diagnosed malignancy worldwide and regularly presents in the head and neck region. As a result, dental professionals are in a key position to identify suspected cases and provide an onward referral. The specialist management of these patients requires a team approach. Although surgery is the mainstay of treatment, radiotherapy may be employed as a definitive or adjuvant treatment modality. This article provides an overview of the epidemiology, presentation and management of non-melanoma skin cancer as well as the interdisciplinary work between the restorative consultant and radiotherapy department to provide an innovative custom-made radiotherapy bolus. CPD/Clinical Relevance: To raise awareness of the presentation and management of non-melanoma skin cancer and the role of the restorative dentist within the multidisciplinary team.
Comparison of the outcome after anterior cervical ossified posterior longitudinal ligament en bloc resection versus posterior total laminectomy and fusion in patients with ossification of the cervical posterior longitudinal ligament: a prospective randomized controlled trial
Authors: Cao Bing , Chen Jingxuan , Yuan Bo , Sun Yanqing , Zhou Shengyuan , Zhao Yin , Xu Zheng , Tang Yifan , Chen Xiongsheng 
Published: March 2023

AimsThe optimal procedure for the treatment of ossification of the posterior longitudinal ligament (OPLL) remains controversial. The aim of this study was to compare the outcome of anterior cervical ossified posterior longitudinal ligament en bloc resection (ACOE) with posterior laminectomy and fusion with bone graft and internal fixation (PTLF) for the surgical management of patients with this condition.MethodsBetween July 2017 and July 2019, 40 patients with cervical OPLL were equally randomized to undergo surgery with an ACOE or a PTLF. The clinical and radiological results were compared between the two groups.ResultsThe Japanese Orthopaedic Association (JOA) score and recovery rate in the ACOE group were significantly higher than those in the PTLF group during two years postoperatively, provided that the canal occupying ratio (COR) was > 50%, or the K-line was negative. There was no significant difference in JOA scores and rate of recovery between the two groups in those in whom the COR was < 50%, or the K-line was positive. There was no significant difference in the Cobb angle between C2 and C7, sagittal vertical axis, cervical range of motion (ROM), and complications between the two groups.ConclusionCompared with PTLF, ACOE is a preferred surgical approach for the surgical management of patients with cervical OPLL in that it offers a better therapeutic outcome when the COR is > 50%, or the K-line is negative, and it also preserves better cervical curvature and sagittal balance. The prognosis of ACOE is similar to that of PTLE when the COR is < 50%, or the K-line is positive.Cite this article: Bone Joint J 2023;105-B(4):412–421.
Long-term functional outcome of secondary shoulder surgery in brachial plexus birth palsy patients
Authors: de Joode Stijn G. C. J. , Meijer Remco , Samijo Steven , Heymans Marion J. L. F. , Chen Neal , van Rhijn Lodewijk W. , Schotanus Martijn G. M. 
Published: March 2023

AimsMultiple secondary surgical procedures of the shoulder, such as soft-tissue releases, tendon transfers, and osteotomies, are described in brachial plexus birth palsy (BPBP) patients. The long-term functional outcomes of these procedures described in the literature are inconclusive. We aimed to analyze the literature looking for a consensus on treatment options.MethodsA systematic literature search in healthcare databases (PubMed, Embase, the Cochrane library, CINAHL, and Web of Science) was performed from January 2000 to July 2020, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The quality of the included studies was assessed with the Cochrane ROBINS-I risk of bias tool. Relevant trials studying BPBP with at least five years of follow-up and describing functional outcome were included.ResultsOf 5,941 studies, 19 were included after full-text screening. A total of 15 surgical techniques were described. All studies described an improvement in active external rotation (range 12° to 128°). A decrease in range of motion and Mallet score after long-term (five to 30 years) follow-up compared to short-term follow-up was seen in most studies.ConclusionThe literature reveals that functional outcome increases after different secondary procedures, even in the long term. Due to the poor methodological quality of the included studies and the variations in indication for surgery and surgical techniques described, a consensus on the long-term functional outcome after secondary surgical procedures in BPBP patients cannot be made.Cite this article: Bone Joint J 2023;105-B(4):455–464.
Notes on Rayleigh scattering in lidar signals: erratum
Authors: Adam Mariana 
Published: March 2023

In this erratum Eqs. (10) and (11) are corrected. Note that the routines created to perform the calculations were correct and thus, all the calculations in the paper [Appl. Opt. 51, 2135 (2012)APOPAI0003-693510.1364/AO.51.002135] were correct.
Estonian adverse events study for multimorbid patients using Estonian Trigger Tool (MUPETT—MUltimorbid Patients—Estonian Trigger Tool). Development of Estonian trigger tool for multimorbid patients. A study protocol for mixed-methods study
Authors: Kannukene Angela , Orrego Carola , Lember Margus , Uusküla Anneli , Põlluste Kaja 
Published: March 2023

Introduction
It is widely recognized that providing healthcare may produce harm to the patient. Different approaches have been developed to measure the burden of adverse events (AEs) to plan and measure the effects of interventions. One of the most widely used instruments is the Trigger Tool, which has previously been modified to be used on various settings and translated into many languages.
Multimorbidity complicates care and may increase the number of AEs patients experience. Currently there is no instrument designed to measure AEs in multimorbid patients. In Estonia, there is currently no validated instrument to measure the burden of AEs.

Aims
The aim of this study will be evaluating the characteristics and ocurrence of AEs in multimorbid patients in hospitalised internal medicine patients of Estonia, and describes the development of a trigger tool for this purpose.

Methods and analysis
We will search for the evidence on measuring AEs in the population of multimorbid patients focusing on trigger tools, and synthesize the data. Data collection of the triggers from the literature will be followed by translating triggers from English to Estonian. An expert multidisciplinary panel will select the suitable triggers for this population. Trigger tool will be pre-tested to assess agreement among professionals and usability of the tool. Validation will be done using 90 medical records. A cross-sectional study in internal medicine departments of two Estonian tertiary care hospitals will be performed to identify the frequency and characteristics of AEs in 960 medical records. We will also provide preventability potential and influencing factors.

Dissemination
Results will be disseminated to healthcare providers and stakeholders at national and international conferences, and as a doctoral medical thesis.
Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population
Authors: Castle Alison C. , Hoeppner Susanne S. , Magodoro Itai M. , Singh Urisha , Moosa Yumna , Bassett Ingrid V. , Wong Emily B. , Siedner Mark J. ,   on behalf of the Vukuzazi Study Team
Published: March 2023

Objective
Tuberculosis (TB) may predispose individuals to the development of diabetes. Such a relationship could have an outsized impact in high-prevalence TB settings. However, few studies have explored this relationship in populations heavily burdened by diabetes and TB.

Methods
We analyzed data from a community-based population cohort that enrolled adults in rural South Africa. Individuals were considered to have prior TB if they self-reported a history of TB treatment. We fitted sex-specific logistic regression models, adjusted for potential clinical and demographic confounders, to estimate relationships between dysglycemia (HBA1c ≥6.5%) and prior TB. Propensity score-matched cohorts accounted for the differential age distributions between comparator groups. We examined the interactions between sex, prior TB, and HIV status.

Results
In the analytic cohort (n = 17,593), the prevalence of prior TB was 13.8% among men and 10.7% among women. Dysglycemia was found in 9.1% of the population, and HIV prevalence was 34.0%. We found no difference in dysglycemia prevalence by prior TB (men OR 0.96, 95% CI 0.60–1.56: women OR 1.05, 95% CI 0.79–1.39). However, there was a qualitative interaction by HIV serostatus, such that among men without HIV, those with a history of TB had a greater prevalence of dysglycemia than those without prior TB (10.1% vs. 4.6%, p = 0.0077). An inverse relationship was observed among men living with HIV (prior TB 3.3% vs. no TB 7.3%, p = 0.0073).

Conclusions
Treated TB disease was not associated with dysglycemia in an HIV-endemic, rural South African population. However, we found a significant interaction between prior TB and HIV status among men, suggesting distinct pathophysiological mechanisms between the two infections that may impact glucose metabolism. Longitudinal studies are needed to better establish a causal effect and underlying mechanisms related to resolved TB, HIV, and diabetes.
Development of clinical prediction rule for the requirement of endoscopic papillary large balloon dilation (EPLBD) on endoscopic CBD stone clearance
Authors: Wongkanong Chote , Patumanond Jayanton , Ratanachu-ek Thawee , Junrungsee Sunhawit , Tantraworasin Apichat 
Published: March 2023

Introduction
To develop a simplified scoring system for clinical prediction of difficulty in CBD stone removal to assist endoscopists working in resource-limited settings in deciding whether to proceed with an intervention or refer patients to a center capable of performing additional procedures and interventions.

Methods
This study included patients with CBD stones who underwent ERCP at Pattani Hospital between August 2017 and December 2021. Retrospective cohort data was collected and patients were categorized into two groups: bile duct stones successfully treated by endoscopic biliary sphincterotomy and extraction compared to the former method combined with EPLBD. We explored potential predictors using multivariable logistic regression. The chosen logistic coefficients were transformed into a scoring system based on risk with internal validation via bootstrapping procedure.

Results
Among the 155 patients who had successful endoscopic therapy for bile duct stones, there were 79 (50.97%) cases of endoscopic biliary sphincterotomy, EPLBD and extraction versus 76 (49.03%) cases without EPLBD. The factors used to derive a scoring system included the size of CBD stones >15 mm, the difference between the stone and distal CBD diameter >2mm, distal CBD arm length <36 mm and stone shape. The score-based model’s area under ROC was 0.88 (95% CI: 0.83, 0.93). For clinical use, the range of scores from 0 to 16, was divided into two subcategories based on CBD stone removal difficulty requiring EPLBD to derive the PPV. For scores <5 and ≥ 5, the PPV was 23.40 (p <0.001) and 93.44 (p <0.001) respectively. The Bootstrap sampling method indicated a prediction ability of 0.88 (AuROC, 95% CI: 0.83, 0.94).

Conclusion
This scoring system has acceptable prediction performance in assisting endoscopists in their choice of stone removal procedure.
Comparing the Intelligibility of Different Varieties of English Through Predicting Learners Comprehension: A Phonetic Experimental Approach
Authors: Wu Chao , Gao Fang 
Published: March 2023

Abstract
In this paper, we focus on the need for measuring the intelligibility of English pronunciation using an automated speech system, and the system proceeded in this feasibility study was tested with 18 speakers coming from six countries representing six types of English (China, Vietnam, Egypt, India, South Africa and the Philippines). Those test candidates were selected carefully to stand for a series of intelligibility, two different approaches, transcription and nonsense, were utilized to test and measure their intelligibility. An automated computer pattern developed for speaking proficiency scoring based on suprasegmental measures was set to predict intelligibility scores. The Pearson’s correlation was 0.743 for transcription construct and 0.819 for the nonsense construct between the human assessed and computer predicted scores. The reliable inter-rater Cronbach’s alpha for the transcription scores was 0.943 and 0.945 for the nonsense intelligibility scores. Basing on the type of intelligibility measure, the computer utilized different suprasegmental measures to predict the score. The computer used 11 measures for the nonsense intelligibility score and eight for the transcription score. Only two features were common to both constructs. These analyses and results of this computer experimental pattern can provide researchers of L2 different perspectives of measuring intelligibility in research afterwards.
Dialogic Learner and Identity Changes in the English Majors at a University for Liberal Arts
Authors: Bian Yongwei 
Published: March 2023

Abstract
This is qualitative research on the development of learner identity (Norton, 2013) via “dialogic learner”—a newly-constructed teaching model. Research subjects were two groups of English majors in 2015 and 2016, each respectively in their first year at a university for liberal arts. Data collection includes learning reflections, interviews and questionnaires. Research findings demonstrate two trajectories of identity changes: The first, found in the first and second groups, was from being one-dimensional learners to becoming multi-dimensional ones; the second, emerging among the second group, was from being passive learners to becoming more active and adequately-prepared ones. This trajectory might further encourage the students in their exploration of multidimensional thinking—the early stage in the evolution of the symbolic competence (Kramsch, 2009), with the possibility of life-long self-education (Gao, 2001).