bluuebunny/crossref_metadata_2025_split huggingface dataset:
All‐Inorganic Perovskite‐Based Monolithic Perovskite/Organic Tandem Solar Cells with 23.21% Efficiency by Dual‐Interface Engineering
Authors: Sun Shuang‐Qiao , Xu Xiuwen , Sun Qi , Yao Qin , Cai Yating , Li Xin‐Yi , Xu Yan‐Lin , He Wei , Zhu Min , Lv Xuan , Lin Francis R. , Jen Alex K.‐Y. , Shi Tingting , Yip Hin‐Lap , Fung Man‐Keung , Xie Yue‐Min 
Published: February 2023

AbstractMonolithic perovskite/organic tandem solar cells (POTSCs) have significant advantages in next‐generation flexible photovoltaics, owing to their capability to overcome the Shockley–Queisser limit and facile device integration. However, the compromised sub‐cells performance challenges the fabrication of high‐efficiency POTSCs. Especially for all‐inorganic wide‐bandgap perovskite front sub‐cells (AIWPSCs) based n‐i‐p structured POTSCs (AIPOTSCs), for which the power conversion efficiency (PCE) is much lower than organic–inorganic mixed‐halide wide‐bandgap perovskite based POTSCs. Herein, an ionic liquid, methylammonium formate (MAFm), based dual‐interface engineering approach is developed to modify the bottom and top interfaces of wide‐bandgap CsPbI2Br films. In particular, the Fm− group of MAFm can effectively passivate the interface defects, and the top interface modification can facilitate the formation of uniform perovskite films with enlarged grain size, thereby mitigating the defects and perovskite grain boundaries induced carrier recombination. As a result, CsPbI2Br‐based AIWPSCs with a high PCE of 17.0% and open‐circuit voltage (VOC) of 1.347 V are achieved. By integrating these dual‐interface engineered CsPbI2Br‐based front sub‐cells with the narrow‐bandgap PM6:CH1007‐based rear sub‐cells, a record PCE of 23.21% is obtained for AIPOTSCs, illustrating the potential of AIPOTSCs for achieving high‐efficiency tandem solar cells.
Revealing the spacing effect of neighboring side‐chains in modulating molecular aggregation and orientation of M‐series acceptors
Authors: Ma Yunlong , Luan Shaoxin , Cai Dongdong , Zhang Shu‐Quan , Wang Jin‐Yun , Tu Qisheng , Zhu Yuhang , Zheng Qingdong 
Published: February 2023

AbstractControlling the aggregation of small‐molecule acceptors (SMAs) is essential to obtain an optimal morphology and to improve the photovoltaic performance of polymer solar cells (PSCs). However, reducing intermolecular aggregation of SMAs is usually accompanied by the disruption of compact molecular packing thereby leading to their decreased electron mobilities. Here, two novel M‐series SMAs (MD1T and MD2T) based on ladder‐type heterononacenes with neighboring side‐chains separated by one or two thiophene rings are designed and synthesized. It is found that shortening the spacing of the neighboring side‐chains of the SMAs can greatly alleviate the intermolecular aggregation and alter the molecular orientation from bimodal edge‐on/face‐on to predominant face‐on while maintaining the compact molecular packing. As a result, a more favorable morphology with smaller domain sizes is formed for the MD1T‐based blend films, which greatly improves the charge generation and charge transport for the corresponding PSCs. The best‐performing MD1T‐based device affords an efficiency of 12.43%, over seven times higher than that of the MD2T‐based device. This work reveals the importance of the spacing between the neighboring side‐chains in modulating the molecular aggregation and active layer morphology, and the obtained structure‐performance relationships shall provide important guidance for designing highly efficient SMAs.
Updated imaging and phylogenetic comparative methods reassess relative temporal lobe size in anthropoids and modern humans
Authors: Pearson Alannah , Bruner Emiliano , Polly P. David 
Published: February 2023

AbstractObjectivesTwo decades ago, Rilling and Seligman, hereafter abbreviated to RAS Study, suggested modern humans had relatively larger temporal lobes for brain size compared to other anthropoids. Despite many subsequent studies drawing conclusions about the evolutionary implications for the emergence of unique cerebral specializations in Homo sapiens, no re‐assessment has occurred using updated methodologies.MethodsWe reassessed the association between right temporal lobe volume (TLV) and right hemisphere volume (HV) in the anthropoid brain. In a sample compiled de novo by us, T1‐weighted in vivo Magnetic Resonance Imaging (MRI) scans of 11 extant anthropoid species were calculated by‐voxel from the MRI and the raw data from RAS Study directly compared to our sample. Phylogenetic Generalized Least‐Squares (PGLS) regression and trait‐mapping using Blomberg's K (kappa) tested the correlation between HV and TLV accounting for anthropoid phylogeny, while bootstrapped PGLS regressions tested difference in slopes and intercepts between monkey and ape subsamples.ResultsPGLS regressions indicated statistically significant correlations (r2 < 0.99; p ≤ 0.0001) between TLV and HV with moderate influence from phylogeny (K ≤ 0.42). Bootstrapped PGLS regression did not show statistically significant differences in slopes between monkeys and apes but did for intercepts. In our sample, human TLV was not larger than expected for anthropoids.DiscussionUpdated imaging, increased sample size and advanced statistical analyses did not find statistically significant results that modern humans possessed a disproportionately large temporal lobe volume compared to the general anthropoid trend. This has important implications for human and non‐human primate brain evolution.
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN‐derived networks and highlights causal links in Alzheimer's disease
Authors: Shi Liu , Xu Jin , Green Rebecca , Wretlind Asger , Homann Jan , Buckley Noel J. , Tijms Betty M. , Vos Stephanie J. B. , Lill Christina M. , Kate Mara ten , Engelborghs Sebastiaan , Sleegers Kristel , Frisoni Giovanni B. , Wallin Anders , Lleó Alberto , Popp Julius , Martinez‐Lage Pablo , Streffer Johannes , Barkhof Frederik , Zetterberg Henrik , Visser Pieter Jelle , Lovestone Simon , Bertram Lars , Nevado‐Holgado Alejo J. , Proitsi Petroula , Legido‐Quigley Cristina 
Published: February 2023

AbstractIntroductionThis study employed an integrative system and causal inference approach to explore molecular signatures in blood and CSF, the amyloid/tau/neurodegeneration [AT(N)] framework, mild cognitive impairment (MCI) conversion to Alzheimer's disease (AD), and genetic risk for AD.MethodsUsing the European Medical Information Framework (EMIF)‐AD cohort, we measured 696 proteins in cerebrospinal fluid (n = 371), 4001 proteins in plasma (n = 972), 611 metabolites in plasma (n = 696), and genotyped whole‐blood (7,778,465 autosomal single nucleotide epolymorphisms, n = 936). We investigated associations: molecular modules to AT(N), module hubs with AD Polygenic Risk scores and APOE4 genotypes, molecular hubs to MCI conversion and probed for causality with AD using Mendelian randomization (MR).ResultsAT(N) framework associated with protein and lipid hubs. In plasma, Proprotein Convertase Subtilisin/Kexin Type 7 showed evidence for causal associations with AD. AD was causally associated with Reticulocalbin 2 and sphingomyelins, an association driven by the APOE isoform.DiscussionThis study reveals multi‐omics networks associated with AT(N) and causal AD molecular candidates.
Sex differences in dementia risk and risk factors: Individual‐participant data analysis using 21 cohorts across six continents from the COSMIC consortium
Authors: Gong Jessica , Harris Katie , Lipnicki Darren M. , Castro‐Costa Erico , Lima‐Costa Maria Fernanda , Diniz Breno S. , Xiao Shifu , Lipton Richard B. , Katz Mindy J. , Wang Cuiling , Preux Pierre‐Marie , Guerchet Maëlenn , Gbessemehlan Antoine , Ritchie Karen , Ancelin Marie‐Laure , Skoog Ingmar , Najar Jenna , Sterner Therese Rydberg , Scarmeas Nikolaos , Yannakoulia Mary , Kosmidis Mary H. , Guaita Antonio , Rolandi Elena , Davin Annalisa , Gureje Oye , Trompet Stella , Gussekloo Jacobijn , Riedel‐Heller Steffi , Pabst Alexander , Röhr Susanne , Shahar Suzana , Singh Devinder Kaur Ajit , Rivan Nurul Fatin Malek , Boxtel Martin van , Köhler Sebastian , Ganguli Mary , Chang Chung‐Chou , Jacobsen Erin , Haan Mary , Ding Ding , Zhao Qianhua , Xiao Zhenxu , Narazaki Kenji , Chen Tao , Chen Sanmei , Ng Tze Pin , Gwee Xinyi , Numbers Katya , Mather Karen A. , Scazufca Marcia , Lobo Antonio , De‐la‐Cámara Concepción , Lobo Elena , Sachdev Perminder S. , Brodaty Henry , Hackett Maree L. , Peters Sanne A. E. , Woodward Mark ,   for the Cohort Studies of Memory in an International Consortium (COSMIC)
Published: February 2023

AbstractIntroductionSex differences in dementia risk, and risk factor (RF) associations with dementia, remain uncertain across diverse ethno‐regional groups.MethodsA total of 29,850 participants (58% women) from 21 cohorts across six continents were included in an individual participant data meta‐analysis. Sex‐specific hazard ratios (HRs), and women‐to‐men ratio of hazard ratios (RHRs) for associations between RFs and all‐cause dementia were derived from mixed‐effect Cox models.ResultsIncident dementia occurred in 2089 (66% women) participants over 4.6 years (median). Women had higher dementia risk (HR, 1.12 [1.02, 1.23]) than men, particularly in low‐ and lower‐middle‐income economies. Associations between longer education and former alcohol use with dementia risk (RHR, 1.01 [1.00, 1.03] per year, and 0.55 [0.38, 0.79], respectively) were stronger for men than women; otherwise, there were no discernible sex differences in other RFs.DiscussionDementia risk was higher in women than men, with possible variations by country‐level income settings, but most RFs appear to work similarly in women and men.
Endogenous Enzyme‐Operated Spherical Nucleic Acids for Cell‐Selective Protein Capture and Localization Regulation
Authors: Liu Qing , Huang Yuanyu , Li Lele , Li Zhengping , Li Mengyuan 
Published: February 2023

AbstractPrecise regulation of protein activity and localization in cancer cells is crucial to dissect the function of the protein‐involved cellular network in tumorigenesis, but there is a lack of suitable methodology. Here we report the design of enzyme‐operated spherical nucleic acids (E‐SNAs) for manipulation of the nucleocytoplasmic translocation of proteins with cancer‐cell selectivity. The E‐SNAs are constructed by programmable engineering of aptamer‐based modules bearing enzyme‐responsive units in predesigned sites and further combination with SNA nanotechnology. We demonstrate that E‐SNAs are able to regulate cytoplasmic‐to‐nuclear shuttling of RelA protein efficiently and specifically in tumor cells, while they remain inactive in normal cells due to insufficient enzyme expression. We further confirmed the generality of this strategy by investigating the enzyme‐modulated inhibition/activation of thrombin activity by varying the aptamer‐based design.
Cd/Pt Precursor Solution for Solar H2 Production and in situ Photochemical Synthesis of Pt Single‐atom Decorated CdS Nanoparticles
Authors: Sharma Pankaj , Sharma Monika , Dearg Malcolm , Wilding Martin , Slater Thomas J. A. , Catlow C. Richard A. 
Published: February 2023

AbstractDespite extensive efforts to develop high‐performance H2 evolution catalysts, this remains a major challenge. Here, we demonstrate the use of Cd/Pt precursor solutions for significant photocatalytic H2 production (154.7 mmol g−1 h−1), removing the need for a pre‐synthesized photocatalyst. In addition, we also report simultaneous in situ synthesis of Pt single‐atoms anchored CdS nanoparticles (PtSA‐CdSIS) during photoirradiation. The highly dispersed in situ incorporation of extensive Pt single atoms on CdSIS enables the enhancement of active sites and suppresses charge recombination, which results in exceptionally high solar‐to‐hydrogen conversion efficiency of ≈1 % and an apparent quantum yield of over 91 % (365 nm) for H2 production. Our work not only provides a promising strategy for maximising H2 production efficiency but also provides a green process for H2 production and the synthesis of highly photoactive PtSA‐CdSIS nanoparticles.
Manipulation of the Buried Interface for Robust Formamidinium‐based Sn−Pb Perovskite Solar Cells with NiOxHole‐Transport Layers
Authors: Zhou Yuan , Wang Zhen , Jin Junjun , Zhang Xiang , Zou Junjie , Yao Fang , Zhu Zhenkun , Cui Xiaxia , Zhang Dan , Yu Yanhua , Chen Cong , Zhao Dewei , Cao Qiang , Lin Qianqian , Tai Qidong 
Published: February 2023

AbstractLow band gap tin‐lead perovskite solar cells (Sn−Pb PSCs) are expected to achieve higher efficiencies than Pb‐PSCs and regarded as key components of tandem PSCs. However, the realization of high efficiency is challenged by the instability of Sn2+and the imperfections at the charge transfer interfaces. Here, we demonstrate an efficient ideal band gap formamidinium (FA)‐based Sn−Pb (FAPb0.5Sn0.5I3) PSC, by manipulating the buried NiOx/perovskite interface with 4‐hydroxyphenethyl ammonium halide (OH‐PEAX, X=Cl−, Br−, or I−) interlayer, which exhibits fascinating functions of reducing the surface defects of the NiOxhole transport layer (HTL), enhancing the perovskite film quality, and improving both the energy level matching and physical contact at the interface. The effects of different halide anions have been elaborated and a 20.53 % efficiency is obtained with OH‐PEABr, which is the highest one for FA‐based Sn−Pb PSCs using NiOxHTLs. Moreover, the device stability is also boosted.
Transesterification of waste cooking oil with a commercial liquid biocatalyst: Key information revised and new insights
Authors: Mateos Paula S. , Casella Mónica L. , Briand Laura E. , Matkovic Silvana R. 
Published: February 2023

AbstractThe transesterification of the waste cooking oil (WCO) with various linear alcohols (C1 to C4) using the commercial biocatalyst Eversa® Transform in its liquid form is addressed in this investigation. The influence of the amount of the liquid formulation of lipase Eversa® Transform, nature of alcohol, oil to alcohol molar ratio and water addition in the transesterification of fresh sunflower oil and WCO was investigated. In addition, an innovative combination of that fungal based biocatalyst with a native vegetable lipase, known as Araujia sericifera (ASL), in a liquid formulation fashion was investigated. The assays carried out at 35°C for 24 h, an oil: alcohol molar ratio of 1:6.8, 2% v/w water added and 1% v/w of biocatalyst allowed to obtain up to 90% conversion and yield towards fatty acid methyl, ethyl and propyl esters. In the particular case of 1‐butanol (C4) a 79% conversion and 72% yield to the esters was obtained. The biocatalyst maintains about 60% of its activity in the conversion of glycerides and yield towards the esters. The combination of process using Eversa® Transform and then the ASL lipase in the transesterification of the WCO probed efficient in the conversion of triglycerides using 1‐butanol. A shift from 73 wt % of fatty acid butyl esters (FABE) towards 90 wt % was achieved.
Improved early and late continence following robot‐assisted radical prostatectomy with concurrent bladder neck fascial sling (RoboSling)
Authors: Leslie Scott , Jackson Stuart , Broe Mark , van Diepen Danielle C. , Stanislaus Christina , Steffens Daniel , McClintock George , Kim Sia , Jeffery Nicola , Fallot Jeremy , Ahmadi Nariman , Vasilaras Arthur , Sved Paul , Chan Lewis , Thanigasalam Ruban 
Published: February 2023

AbstractObjectiveTo describe a novel RoboSling technique performed at the time of robot‐assisted radical prostatectomy (RARP) and its utility for enhancing urinary function recovery postoperatively.Materials and MethodsThe surgical technique involves harvesting a vascularised, fascial flap from the peritoneum on the posterior aspect of the bladder. Following completion of prostatectomy, the autologous flap is tunnelled underneath the bladder and incorporated into the rectourethralis and vertical longitudinal detrusor fibres at the posterior bladder neck with a modified Rocco suture. After urethra‐vesical anastomosis is completed, the corners of the flap are hitched up to Cooper's ligament bilaterally with V‐Loc sutures, tensioned and secured creating a bladder neck sling. A prospective, longitudinal cohort study was performed of 193 consecutive patients undergoing RARP between December 2016 and September 2019. The first 163 patients underwent standard RARP, and the last 30 patients had the RoboSling technique performed concurrently. Continence outcomes were the primary outcomes assessed using pad number and Expanded Prostate Cancer Composite (EPIC)‐urinary domain questionnaire. Operative time (OT), estimated blood loss (EBL), complications and oncological outcomes were secondary outcomes.ResultsThe two groups were comparable for demographics and clinicopathological variables. At 3 months, zero pad usage (p = 0.005) and continence rates, defined as EPIC score ≥ 85 (p = 0.007), were both higher in the RoboSling group. EBL, complication rate and positive surgical margin rate did not differ between the two groups. Superior zero pad usage was observed at 1 year in the RoboSling group (p = 0.029). The RoboSling technique added on average 16 min to OT.ConclusionsThe RoboSling procedure at the time of RARP was associated with earlier return to continence without negatively impacting other postoperative outcomes. This improvement in continence outcomes was maintained long term.
Stratifying the risk of ovarian cancer incidence by histologic subtypes in the Korean Epithelial Ovarian Cancer Study (Ko‐EVE)
Authors: Sung Soseul , Hong Youjin , Kim Byoung‐Gie , Choi Ji‐Yeob , Kim Jae Weon , Park Sang‐Yoon , Kim Jae‐Hoon , Kim Yong‐man , Lee Jong‐Min , Kim Tae Jin , Park Sue K. 
Published: February 2023

AbstractIntroductionThis study aimed to verify the association between ovarian cancer (OC) and reproductive‐ and lifestyle‐related risk factors stratified by the subtype of OC.MethodsIn this matched case–control study derived from the Korean epithelial ovarian cancer study (Ko‐EVE), we calculated the risk of OC subtypes using odds ratios (ORs) and 95% confidence intervals (95% CIs) in a logistic regression model.ResultsAs a result of matching, 531 cases and 2,124 controls were selected. Smoking had positive association with high‐grade serous (HGS) OC (OR = 2.69, 95% CI = 1.15–6.30), whereas alcohol consumption had positive association with mucinous type (MUC) (OR = 3.63, 95% CI = 1.39–9.49). Obesity (≥30 kg/m2) was associated with clear cell type (CLC) (OR = 4.57, 95% CI = 1.06–19.77). Spontaneous abortion was negatively associated with CLC (OR = 0.34, 95% CI = 0.13–0.90), in contrast to HGS (OR = 1.43, 95% CI = 0.96–2.15). Tubal ligation, hysterectomy, and oophorectomy were associated with decreased risk of HGS (OR = 0.14, 95% CI = 0.05–0.39; OR = 0.23, 95% CI = 0.07–0.73; OR = 0.28, 95% CI = 0.08–0.97, respectively). Early menarche was strongly associated with increased risk of CLC, but not MUC (OR = 6.11, 95% CI = 1.53–24.42; OR = 3.23, 95% CI = 0.98–10.86). Further, childbirth (≥2 times) was negatively associated with endometrioid type OC and CLC (OR = 0.11, 95% CI = 0.04–0.35; OR = 0.12, 95% CI = 0.02–0.37, respectively). Oral contraceptives and hormone replacement therapy were negatively associated with OC (OR = 0.61, 95% CI = 0.40–0.93; OR = 0.51, 95% CI = 0.32–0.80, respectively), and similar negative associations were also observed in HGS (OR = 0.69; OR = 0.60, respectively). Associations between family history of breast cancer and OC, regular exercise (≥5/week), and artificial abortion and OC were similar across all subtypes (OR = 3.92; OR = 0.41; OR = 0.72, respectively).ConclusionA heterogeneous association between some risk factors and the incidence of each subtype of epithelial OC was observed, suggesting that the carcinogenic mechanisms of each subtype may be partly different.
Design of Multicationic Copper‐Bearing Layered Double Hydroxides for Catalytic Application in Biorefinery
Authors: Awan Iqra Zubair , Ho Phuoc Hoang , Beltrami Giada , Gimello Olinda , Cacciaguerra Thomas , Gaudin Pierrick , Tanchoux Nathalie , Albonetti Stefania , Martucci Annalisa , Cavani Fabrizio , Tichit Didier , Di Renzo Francesco 
Published: February 2023

AbstractEthanol has been used as a renewable hydrogen‐donor in the conversion of a lignin model molecule in subcritical conditions. Noble metal‐free porous mixed oxides, obtained by activation of Cu−Ni−Al and Cu−Ni−Fe layered double hydroxide (LDH) precursors, have been used as heterogeneous catalysts for Meerwein‐Ponndorf‐Verley (MPV) hydrogen transfer and further hydrogenation by ethanol dehydrogenation products. Both the Cu/(Cu+Ni) ratio and the nature of the trivalent cation (Al or Fe) affect the activity of the catalysts, as well as the selectivity towards the different steps of the hydrogenation reactions and the cleavage of lignin‐like phenylether bonds. Accounting for the peculiar behaviour of Cu2+ and M(III) cations in the synthesis of LDHs, the coprecipitation of the precursors has been monitored by titration experiments. Structural and textural properties of the catalysts are closely related to the composition of the LDH precursors.
Heterophenoquinones: Tuning Optoelectronics and Electrochromicity
Authors: Amberg Willi M. , Intorp Sebastian N. , Dmitrieva Evgenia , Popov Alexey A. , Rominger Frank , Freudenberg Jan , Bunz Uwe H. F. 
Published: February 2023

AbstractWe report the synthesis and optoelectronic properties of 16 thiophene‐based heterophenoquinones. These compounds were accessed in a convergent and modular approach, allowing for their efficient synthesis. Tuning of the optical band gap was achieved through π‐extension by annulation of a benzene or tropone moiety to the thiophene, oxidation, change of the heteroatom or by attachment of a donor substituent to the thiophene core. The resulting compounds display intense colors covering the entire visible spectrum. We identified structure‐property relationships and their impact on the HOMO and LUMO levels. Additionally, these materials change color upon reduction and according to in situ ultraviolet‐visible‐near infrared (UV‐vis‐NIR) and electron paramagnetic resonance (EPR) spectro‐electrochemistry, they are promising electrochromes with cathodic color changes. Seven different electrochromic devices were constructed which all displayed a change in color upon reduction, demonstrating the potential of these new dyes in for example tintable glass.