bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synovial sarcoma of female urethra: a case report and review of the literature
Authors: Cui Wei , Liao Yuan-Jian , Su Peng , Yang Hua , Zhang Neng 
Published: July 2023

AbstractSynovial sarcoma (SS) is a rare malignant soft tissue sarcoma that originates from primitive mesenchymal cells with epithelial differentiation potential. It is most commonly found in the limbs and trunk. In the urinary system, it is mostly found in the kidneys. However, synovial sarcomas originating from the external urethra are extremely rare. Only one case of synovial sarcoma arising from the vulvar urethral orifice has been reported previously, and we report a second case of synovial sarcoma of the urethral orifice. In addition, a total of 16 vulvar synovial sarcomas were identified and the literature are analyzed in this report reviews from 1966 to the present.
Minimally-invasive approach via percutaneous femoral cannulation for the resection of intra-cardiac masses: a single center experience in the Middle-East
Authors: Aluthman Uthman , Ashour Mohammed A. , Bafageeh Salman W. , Chandrakumaran Abivarma , Alrehaili Taraji S. , Abdulrahman Osama A. , Elmahrouk Ahmed F. , Alaamri Shalan , AlGhamdi Saeed A. , Jamjoom Ahmed A. 
Published: July 2023

Abstract
Background
Intra-cardiac masses are rare and challenging lesions with an overall incidence ranging of 0.02–0.2%. Minimally invasive approaches have been recently introduced for surgical resection of these lesions. Here, we evaluated our early experience using minimally invasive techniques in addressing intra-cardiac lesions.

Methodology
This is a retrospective descriptive study conducted between April 2018 to December 2020. All patients were diagnosed with cardiac tumors and treated via a right mini-thoracotomy with cardiopulmonary bypass through femoral cannulation at King Faisal Specialist Hospital and Research Centre, Jeddah.

Results
Myxoma was the most common pathology representing 46% of cases followed by thrombus (27%), leiomyoma (9%), lipoma (9%) and angiosarcoma (9%). All tumors were resected with negative margins. One patient was converted to open sternotomy. Tumor locations were in the right atrium, left atrium, and left ventricle in 5, 3, and 3 patients, respectively. The median ICU stay was 1.33 days. The median length of hospitalization was 5.7 days. There was no 30-days hospital mortality recorded in this cohort.

Conclusion
Our early experience shows that minimally invasive resection can be performed safely and effectively for intra-cardiac masses. The minimally invasive approach using a mini-thoracotomy with percutaneous femoral cannulation can be an effective alternative in resecting intra-cardiac masses that achieves clear margin resection, quick post-operative recovery, and low rates of recurrence for benign lesions.
Xanthoma of rib: a case report and review of the literature
Authors: Mottola Emilia , Adotti Flavia , Pernazza Angelina , Della Rocca Carlo , D’Amati Giulia , Nardis Piergiorgio , Vannucci Jacopo , Bassi Massimiliano , Venuta Federico , Anile Marco 
Published: July 2023

Abstract
Background
Xanthomas are well-circumscribed benign proliferative lesions seen mainly in soft tissues. Usually, they are found in hyperlipidemia and familial hyperlipoproteinemia. Histologically, are characterized by macrophage-like mononuclear cells, multinucleated giant cells and abundant foam cells. The bone involvement, however, is notoriously rare and rib localization is extremely rare.

Case presentation
A 55-year-old man performed a chest X-ray and a subsequent chest Computed Tomography scan showing a rib lesion that was surgically removed and a diagnosis of rib xanthoma was made. The patient presented an unknown condition of hyperlipidemia.

Conclusion
Rib xanthoma can be discovered accidentally and can be helpful in identifying an unrecognized condition of hyperlipidemia.
BCR::ABL1-like acute lymphoblastic leukaemia: a single institution experience on identification of potentially therapeutic targetable cases
Authors: Płotka Anna , Przybyłowicz-Chalecka Anna , Korolczuk Maria , Kanduła Zuzanna , Ratajczak Błażej , Kiernicka-Parulska Jolanta , Mierzwa Anna , Godziewska Katarzyna , Jarmuż-Szymczak Małgorzata , Gil Lidia , Lewandowski Krzysztof 
Published: July 2023

Abstract
Background
BCR::ABL1-like acute lymphoblastic leukaemia (BCR::ABL1-like ALL) is characterized by inferior outcomes. Current efforts concentrate on the identification of molecular targets to improve the therapy results. The accessibility to next generation sequencing, a recommended diagnostic method, is limited. We present our experience in the BCR::ABL1-like ALL diagnostics, using a simplified algorithm.

Results
Out of 102 B-ALL adult patients admitted to our Department in the years 2008–2022, 71 patients with available genetic material were included. The diagnostic algorithm comprised flow cytometry, fluorescent in-situ hybridization, karyotype analysis and molecular testing with high resolution melt analysis and Sanger Sequencing. We recognized recurring cytogenetic abnormalities in 32 patients. The remaining 39 patients were screened for BCR::ABL1-like features. Among them, we identified 6 patients with BCR::ABL1-like features (15.4%). Notably, we documented CRLF2-rearranged (CRLF2-r) BCR::ABL1-like ALL occurrence in a patient with long-term remission of previously CRLF2-r negative ALL.

Conclusions
An algorithm implementing widely available techniques enables the identification of BCR::ABL1-like ALL cases in settings with limited resources.
Comparison of postural sway in individuals with and without dynamic knee valgus
Authors: Karimi Kimia , Seidi Foad , Mousavi Seyed Hamed , Alghosi Mohammad , Morad Nafiseh Homaie 
Published: July 2023

AbstractBackgroundDynamic knee valgus (DKV) is a multi-planar faulty movement pattern that can cause faulty postural control. The primary objective of this study is to investigate the differences in postural sway (PS) between individuals aged 18–30 years old diagnosed with and without DKV.MethodsIn this cross-sectional study, 62 students (39 males and 23 females) with and without DKV (age: 24.58 ± 2.63 years) were selected and assigned to two groups by conducting the single-leg squat test in the screening stage. The Biodex balance system was then employed to compare the two groups in PS. Mann–Whitney U test was conducted to compare the groups in PS (p ≤ 0.05).ResultsThe study’s findings indicate that individuals with DKV did not exhibit any significant differences, compared to those without, about the anterior-posterior stability index (with p values for both static and dynamic situations at 0.309 and 0.198, respectively), medial-lateral stability index (with p values for both static and dynamic situations at 0.883 and 0.500, respectively), and overall stability index (with p values for both static and dynamic situations at 0.277 and 0.086, respectively).ConclusionThough several possible factors could contribute to the lack of significant differences in postural sway between individuals with and without DKV, such as measurement tool differences, variable sensitivity in postural stability tests, and differences in movement variability and test stance, we recommend analyzing postural sway in more functional tasks and with different methodological patterns in future studies. Such research could help develop targeted interventions for individuals with DKV and offer a better understanding of the relationship between postural control and DKV.
In-silico molecular designs to treat neurologic and ophthalmologic diseases caused by sorbitol excess: engineering the Agrobacterium vitis protein
Authors: Sharma Shonit Nair , Hojati Ashkhan , Gnanasambandam Bhargavee , Yerrabelli Rahul S. , Brozek Joshua 
Published: July 2023

AbstractThis work presents the design of a new protein based on the adenosine triphosphate-binding cassette (ABC) transporter solute binding protein (SBP) derived from Agrobacterium vitis, a gram-negative plant pathogen. The Protein Data Bank in Europe’s dictionary of chemical components was utilized to identify sorbitol and D-allitol. Allitol bound to an ABC transporter SBP was identified in the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB). Wizard Pair Fitting and Sculpting tools in PyMOL were used to replace bound allitol with sorbitol. PackMover Python code was used to induce mutations in the ABC transporter SBP’s binding pocket, and changes in free energy for each protein-sorbitol complex were identified. The results indicate that adding charged side chains forms polar bonds with sorbitol in the binding pocket, thus increasing its stabilization. In theory, the novel protein can be used as a molecular sponge to remove sorbitol from tissue and therefore treat conditions affected by sorbitol dehydrogenase deficiency.
Fixed point theorems and applications in p-vector spaces
Authors: Yuan George Xianzhi 
Published: July 2023

AbstractThe goal of this paper is to develop new fixed points for quasi upper semicontinuous set-valued mappings and compact continuous (single-valued) mappings, and related applications for useful tools in nonlinear analysis by applying the best approximation approach for classes of semiclosed 1-set contractive set-valued mappings in locally p-convex and p-vector spaces for $p \in (0, 1]$
p
∈
(
0
,
1
]
. In particular, we first develop general fixed point theorems for quasi upper semicontinuous set-valued and single-valued condensing mappings, which provide answers to the Schauder conjecture in the affirmative way under the setting of locally p-convex spaces and topological vector spaces for $p \in (0, 1]$
p
∈
(
0
,
1
]
; then the best approximation results for quasi upper semicontinuous and 1-set contractive set-valued mappings are established, which are used as tools to establish some new fixed points for nonself quasi upper semicontinuous set-valued mappings with either inward or outward set conditions under various boundary situations. The results established in this paper unify or improve corresponding results in the existing literature for nonlinear analysis, and they would be regarded as the continuation of the related work by Yuan (Fixed Point Theory Algorithms Sci. Eng. 2022:20, 2022)–(Fixed Point Theory Algorithms Sci. Eng. 2022:26, 2022) recently.
Carriage of ESBL-producing Klebsiella pneumoniae and Escherichia coli among children in rural Ghana: a cross-sectional study
Authors: Akenten Charity Wiafe , Khan Neyaz Ahmed , Mbwana Joyce , Krumkamp Ralf , Fosu Dennis , Paintsil Ellis Kobina , Boahen Kennedy Gyau , Osei-Mensa James , Maiga-Ascofare Oumou , May Jürgen , Obiri-Danso Kwasi , Phillips Richard Odame , Ofori Linda Aurelia , Dekker Denise 
Published: July 2023

Abstract
Background
Extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae (ESBL-KP) and Escherichia coli (ESBL-EC) present a high burden in both communities and healthcare sectors, leading to difficult-to-treat infections. Data on intestinal carriage of ESBL-KP and ESBL-EC in children is scarce, especially in sub-Saharan African countries. We provide data on faecal carriage, phenotypic resistance patterns, and gene variation of ESBL-EC and ESBL-KP among children in the Agogo region of Ghana.

Methods
From July to December 2019, fresh stool samples were collected within 24 h from children < 5 years with and without diarrhoea attending the study hospital. The samples were screened for ESBL-EC and ESBL-KP on ESBL agar and confirmed using double-disk synergy testing. Bacterial identification and an antibiotic susceptibility profile were performed using the Vitek 2 compact system (bioMérieux, Inc.). ESBL genes, blaSHV, blaCTX-M, and blaTEM were identified by PCR and further sequencing.

Results
Of the 435 children recruited, stool carriage of ESBL-EC and ESBL-KP was 40.9% (n/N = 178/435) with no significant difference in prevalence between children with diarrhoea and non-diarrhoea. No association between ESBL carriage and the age of the children was found. All isolates were resistant to ampicillin and susceptible to meropenem and imipenem. Both ESBL-EC and ESBL-KP isolates showed over 70% resistance to tetracycline and sulfamethoxazole-trimethoprim. Multidrug resistance was observed in over 70% in both ESBL-EC and ESBL-KP isolates. The blaCTX-M-15 was the most prevalent ESBL gene detected. blaCTX-M-27, blaCTX-M-14, and blaCTX-M-14b were found in non-diarrhoea stools of children, whereas blaCTX-M-28 was found in both the diarrhoea and non-diarrhoea patient groups.

Conclusions
The carriage of ESBL-EC and ESBL-KP among children with and without diarrhoea in the Agogo community with a high prevalence of blaCTX-M-15 is noteworthy, highlighting the importance of both the population as a possible reservoir. This study reports for the first time the ESBL gene blaCTX-M-28 among the studied populations in Ghana.
The incidence of nosocomial bloodstream infection and urinary tract infection in Australian hospitals before and during the COVID-19 pandemic: an interrupted time series study
Authors: Mitchell Brett G , Stewardson Andrew J , Kerr Lucille , Ferguson John K , Curtis Stephanie , Busija Ljoudmila , Lydeamore Michael J , Graham Kirsty , Russo Philip L 
Published: July 2023

Abstract
Background
The COVID-19 pandemic has had a significant impact on healthcare including increased awareness of infection prevention and control (IPC). The aim of this study was to explore if the heightened awareness of IPC measures implemented in response to the pandemic influenced the rates of healthcare associated infections (HAI) using positive bloodstream and urine cultures as a proxy measure.

Methods
A 3 year retrospective review of laboratory data from 5 hospitals (4 acute public, 1 private) from two states in Australia was undertaken. Monthly positive bloodstream culture data and urinary culture data were collected from January 2017 to March 2021. Occupied bed days (OBDs) were used to generate monthly HAI incidence per 10,000 OBDs. An interrupted time series analysis was undertaken to compare incidence pre and post February 2020 (the pre COVID-19 cohort and the COVID-19 cohort respectively). A HAI was assumed if positive cultures were obtained 48 h after admission and met other criteria.

Results
A total of 1,988 bloodstream and 7,697 urine positive cultures were identified. The unadjusted incident rate was 25.5 /10,000 OBDs in the pre-COVID-19 cohort, and 25.1/10,000 OBDs in the COVID-19 cohort. The overall rate of HAI aggregated for all sites did not differ significantly between the two periods. The two hospitals in one state which experienced an earlier and larger outbreak demonstrated a significant downward trend in the COVID-19 cohort (p = 0.011).

Conclusion
These mixed findings reflect the uncertainty of the effect the pandemic has had on HAI’s. Factors to consider in this analysis include local epidemiology, differences between public and private sector facilities, changes in patient populations and profiles between hospitals, and timing of enhanced IPC interventions. Future studies which factor in these differences may provide further insight on the effect of COVID-19 on HAIs.
Visions of recovery: a cross-diagnostic examination of eating disorder pro-recovery communities on TikTok
Authors: Greene Amanda K. , Norling Hannah N. , Brownstone Lisa M. , Maloul Elana K. , Roe Caity , Moody Sarah 
Published: July 2023

AbstractIndividuals seeking support or inspiration for eating disorder recovery may turn to pro-recovery content on social media sites such as TikTok. While research has thus far treated pro-recovery social media as a fairly homogeneous space, many pro-recovery hashtags single out particular eating disorder diagnoses. This exploratory study used codebook thematic analysis of 241 popular pro-recovery videos on TikTok to compare the presentation of eating disorders and eating disorder recovery across five different diagnosis-specific hashtags: #anarecovery, #arfidrecovery, #bedrecovery, #miarecovery, and #orthorexiarecovery. These hashtags refer to the following eating disorder diagnoses respectively: anorexia nervosa, avoidant restrictive food intake disorder, binge eating disorder, bulimia nervosa, and orthorexia nervosa. Our analysis generated the following qualitative themes across the entire dataset: (1) centrality of food to eating disorders and recovery, (2) what eating disorders look and feel like, (3) recovery as a process, (4) getting and giving help, and (5) negotiating diet culture in recovery. To supplement our qualitative findings and facilitate cross-diagnostic comparisons, we also conducted one-way ANOVAs and chi-square tests to probe for statistically significant differences in audience engagement and code prevalence across the different hashtags. Our results indicate that there are clear differences in how recovery is envisioned on TikTok based on which diagnostic hashtags are employed. Such variations in how different eating disorders are imagined on popular social media demand further investigation and clinical consideration.
Chinese TikTok (Douyin) challenges and body image concerns: a pilot study
Authors: Hu Shuchen , Gan Jasmine , Shi Victoria , Krug Isabel 
Published: July 2023

AbstractBackgroundSocial media content on Western platforms promoting thinness, orthinspiration, has been found to negatively affect body image perception of users. Less is known about non-Western social media use and its effects on body image concerns. Chinese TikTok, known as Douyin, is a popular short video platform with 600 million daily active users. Recent trends on Douyin encourage users to demonstrate thinness through participation in ‘body challenges’. This paper argues that such content is comparable to thinspiration, however, to date hardly any research has been undertaken on these challenges. Thus, this pilot study aimed to analyse the content of three viral challenges and investigate their impact on Douyin users.MethodsThirty most viewed videos were collected for three challenges (N = 90): the Coin challenge, the A4 Waist challenge, and the Spider leg challenge. Videos were coded for variables relating to thin idealisation, including thin praise, sexualisation and objectification, and analysed through content analytic methods. Video comments (N ≈ 5500) were analysed through thematic analysis, and main themes were identified.ResultsPreliminary findings showed that participants who objectified their bodies to a greater extent expressed more negative body image concerns. In addition, comments on the videos had themes of thin praise, self-comparison, and promotion of dieting behaviours. In particular, videos of the A4 Waist challenge were found to incite more negative self-comparison in viewers.ConclusionPreliminary findings suggest all three challenges promote the thin ideal and encourage body image concerns. Further research about the broader impact of body challenges is needed.
Probing shallow subsurface structures in the arc-continent collision suture zone near Hualien in Eastern Taiwan with magnetotelluric methods
Authors: Chang Ping-Yu , Amania Haiyina Hasbia , Fikri Azhar , Puntu Jordi Mahardika , Lin Ding-Jiun , Kuo Chun-Hsiang , Wang Chien-Ying , Chang Wen-Yen 
Published: July 2023

AbstractWe used the magnetotelluric method (MT) to investigate near-surface structures at the northern end of the Longitudinal Valley in Hualien City, eastern Taiwan. This valley is considered the suture zone of the arc-continental collision between the Eurasian plate and the Philippine Sea plate, making it crucial to understand the geological settings at its northern end. We conducted MT measurements along the L2 and L3 lines on the north and south sides of the city, respectively. On the L2 survey line to the north of Hualien City, our inverted image indicates that the Tananao metamorphic complex, with a resistivity of several hundred ohm-m, is in vertical contact with sedimentary rock with a resistivity higher than 1000 Ω-m. This vertical contact zone is consistent with the distribution of the Beipu fault. However, the vast area between L2A and L2E is occupied by airports and military facilities, making it challenging to lay out survey stations to clearly analyze critical regional structures such as the Beipu and Milun faults. The 2D inversion results of the L3 are consistent with past reflection seismic interpretation results. The resistivity of the metamorphic Yuli Formation, which belongs to the continental basement rock in the west, is less than 200 Ω-m. Its top dips eastward, reaching depths greater than 2.5 km at the eastern end of the L3. The rocks above the metamorphic bedrock, composed of material with a resistivity greater than 1000 Ω-meters, are likely to be sedimentary rocks of the foreland basin. The difference in geological structure between the two survey lines, L2 and L3, may suggest the possible existence of an E-W orienting fault structure in the urban area between the two survey lines. Additionally, the rapid thickening of sedimentary rocks north of Hualien City may provide indirect evidence for the detachment model proposed by Shyu et al. (Tectonophysics 692:295-308, 2016). Further studies are required to resolve the resistivity structures and fault orientations in the urban region between the two survey lines.
Greenhouse gases Observing SATellite 2 (GOSAT-2): mission overview
Authors: Imasu Ryoichi , Matsunaga Tsuneo , Nakajima Masakatsu , Yoshida Yukio , Shiomi Kei , Morino Isamu , Saitoh Naoko , Niwa Yosuke , Someya Yu , Oishi Yu , Hashimoto Makiko , Noda Hibiki , Hikosaka Kouki , Uchino Osamu , Maksyutov Shamil , Takagi Hiroshi , Ishida Haruma , Nakajima Takashi Y. , Nakajima Teruyuki , Shi Chong 
Published: July 2023

AbstractThe Greenhouse gases Observing SATellite 2 (GOSAT-2) was launched in October 2018 as a successor to GOSAT (launched in 2009), the first satellite to specialize in greenhouse gas observations. Compared to the GOSAT sensors, the sensors of GOSAT-2 offer higher performance in most respects. The quality and quantity of data from observations are expected to be improved accordingly. The signal-to-noise ratio (SNR) is better in both the SWIR and TIR bands of TANSO-FTS-2, which is the main sensor of GOSAT-2. This improvement ultimately enhances the accuracy of greenhouse gas concentration analysis. Furthermore, because of the improved SNR in the SWIR band, the northern limit at which data are obtainable in high-latitude regions of the Northern Hemisphere in winter, where observation data have remained unavailable because of weak signal strength, has moved to higher latitudes. As better data are obtained in greater quantities, progress in carbon cycle research for high-latitude regions is anticipated. Moreover, the improvement of SNR in the TIR band is expected to be considerable. Particularly, the resolutions of the vertical concentration distributions of CO2and CH4have been improved drastically. The first function introduced for GOSAT-2 that is not in GOSAT is an intelligent pointing mechanism: a cloud area avoidance function using the in-field camera of TANSO-FTS-2. This function can increase the amounts of observation data globally and can improve the accuracy of CO2emissions estimation and measurements of uptake intensity. The effects are expected to be strong, especially for the tropics because cumulus clouds are the most common cloud type. The intelligent pointing system can avoid the clouds effectively. Another important benefit of TANSO-FTS-2 is that the wavelength range of Band 3 of SWIR has been expanded for measuring carbon monoxide (CO). Because CO originates from combustion, it is used to evaluate some effects of human activities in urban areas and biomass burning in fields. Particularly, black carbon-type aerosols can be measured by the sub-sensor, TANSO-CAI-2, to assess biomass burning along with CO2and CO by TANSO-FTS-2.