bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ruthenium‐Assisted Tellurium Abstraction in Bis(thiophen‐2‐yl) Ditelluride
Authors: Taimisto Marjaana , Poropudas Merja J. , Rautiainen J. Mikko , Oilunkaniemi Raija , Laitinen Risto S. 
Published: February 2023

AbstractThe reaction of [RuCl2(CO)3]2 and Te2Tpn2 (Tpn=thiophen‐2‐yl, C4H3S) in the absence of light resulted in the formation of cct‐[RuCl2(CO)2(TeTpn2)2] (1) [cis(Cl)‐cis(CO)‐trans(TeTpn2)] and TeTpn2 (2) together with the precipitation of tellurium. The complex 1 and the monotelluride 2 were characterized by NMR spectroscopy and single‐crystal X‐ray diffraction. The decomposition of Te2Tpn2 to TeTpn2 has been monitored by 125Te NMR spectroscopy and seemed to be faster than the ligand substitution in [RuCl2(CO)3]2 by TeTpn2. A catalytic cycle is proposed for the decomposition of Te2Tpn2 to TeTpn2 based on the PBE0‐D3/def2‐TZVP calculations.
The Impact of Fat Deterioration on Formation of Acrylamide in Fried Foods
Authors: Gertz Christian , Aladedunye Felix , Popp Martin , Matthäus Bertrand 
Published: February 2023

AbstractThe current study investigates to what extent the reaction products of thermal degradation directly influence acrylamide formation in French fries. The frying tests at 170 and 180 °C are carried out with rapeseed oil for 32 h with 128 frying cycles. Acrylamide content in French fries is determined by LC‐MS/MS. Oxidative and thermal degradation is followed by measuring total polar compounds (TPC), di‐ and polymerized triacylglycerols (DPTG), monomer oxidized triacylglycerols (MONOX), p‐anisidine value (AnV), mono and di‐acyl‐glycerols (MAG and DAG), acid value (AV), epoxy fatty acids, iodine value (IV), saponification value, and fatty acid composition. During frying, the nature and degradation level of the frying medium have a direct impact on acrylamide formation. It can be shown that the pH‐dependent reaction is strongly inhibited at acid values above 0.5 mg KOH g−1 oil. Acidity measured as AV or FFA is mainly caused by oxidation, and less so by hydrolysis of triacylglycerols (TAG) as assumed up to now. Obviously, acid functional groups formed by oxidation of unsaturated fatty acids bound in TAG can act not only as catalyst for dimerization of TAG but also interact with asparagine as most important precursor for acrylamide formation so that no reaction with carbonyl groups for the formation of acrylamide is necessary.Practical applications: The same acidic functional groups that are known to catalyze the formation of dimeric TAG under frying conditions (160–190 °C, access of oxygen) in a nonradical mechanism apparently can also deactivate asparagine by protonization as a potential precursor for the formation of acrylamide. It is recommended not to reduce acidity of used frying oil by active filter aids below AV ≥ 0.5 as it helps to reduce acrylamide contamination of fried food.
Pain and Parkinson's disease: Current mechanism and management updates
Authors: Viseux Frederic J. F. , Delval Arnaud , Simoneau Martin , Defebvre Luc 
Published: February 2023

AbstractThe aim of this comprehensive review was to provide an overview of pain in Parkinson's disease (PD) by identifying different clinical features and potential mechanisms, and presenting some data on the evaluation and management of pain in PD. PD is a multifocal degenerative and progressive disease, which could affect the pain process at multiple levels. Pain in PD has a multifactorial aetiology, with a dynamic process based on pain intensity, complexity of symptoms, pain pathophysiology and presence of comorbidities. In fact, pain in PD responds to the concept of multimorphic pain, which can evolve, in relation to the different factors, whether they are linked to disease and its management. Understanding the underlying mechanisms will help in guiding of treatment choices. Providing scientific support useful for clinicians and health professionals involved in management of PD, the aim of this review was to bringing practical suggestions and clinical perspectives on the development of a multimodal approach guided by a multidisciplinary clinical intervention through a combination of pharmacological and rehabilitative approaches, to manage pain to improve the quality of life on individuals with PD.
Pain modulates early sensory brain responses to task‐irrelevant emotional faces
Authors: Xu Qianru , Ye Chaoxiong , Li Xueqiao , Zhao Guoying , Astikainen Piia 
Published: February 2023

AbstractBackgroundPain can have a significant impact on an individual's life, as it has both cognitive and affective consequences. However, our understanding of how pain affects social cognition is limited. Previous studies have shown that pain, as an alarm stimulus, can disrupt cognitive processing when focal attention is required, but whether pain also affects task‐irrelevant perceptual processing remains unclear.MethodsWe examined the effect of laboratory‐induced pain on event‐related potentials (ERPs) to neutral, sad and happy faces before, during and after a cold pressor pain. ERPs reflecting different stages of visual processing (P1, N170 and P2) were analysed.ResultsPain decreased the P1 amplitude for happy faces and increased the N170 amplitude for happy and sad faces compared to the pre‐pain phase. The effect of pain on N170 was also observed in the post‐pain phase. The P2 component was not affected by pain.ConclusionsOur results suggest that pain alters both featural (P1) and structural face‐sensitive (N170) visual encoding of emotional faces, even when the faces are irrelevant to the task. While the effect of pain on initial feature encoding seemed to be disruptive and specific to happy faces, later processing stages showed long‐lasting and increased activity for both sad and happy emotional faces.SignificanceThe observed alterations in face perception due to pain may have consequences for real‐life interactions, as fast and automatic encoding of facial emotions is important for social interactions.
The effect of high versus low cognitive load on the development of nociceptive hypersensitivity: The roles of sympathetic arousal, sex and pain‐related fear
Authors: Meyers Elke , Vlaeyen Johan W. S. , van den Broeke Emanuel N. , von Leupoldt Andreas , Palmer Andrew J. , Torta Diana M. 
Published: February 2023

AbstractBackgroundAccording to limited‐capacity theories of attention, less attentional resources remain available when engaging in a high‐ versus a low‐demanding cognitive task. This may reduce the perceived intensity and the evoked cortical responses of concomitant nociceptive stimuli. Whether and how the competition for limited attentional resources between a cognitive task and pain impacts the development of long‐lasting hypersensitivity is unclear.MethodsEighty‐four healthy participants were randomized into a low or high cognitive load group. Low‐frequency electrical stimulation (LFS) of the skin was used to induce secondary hypersensitivity. We hypothesized that performing the high‐load task during LFS would reduce the development of hypersensitivity. We examined whether painfulness, nonpain‐related sympathetic arousal, or sex related to hypersensitivity, by assessing intensity and unpleasantness of mechanical pinprick stimulation. During task execution, we recorded steady‐state evoked potentials evoked by LFS and skin conductance level for sympathetic arousal. Afterwards, participants reported task difficulty and LFS‐related fear. For the primary outcomes, we used mixed analysis of variances.ResultsThe results confirmed the difference in cognitive load. Although LFS successfully induced hypersensitivity, the high‐load task did not reduce its development. Next, the steady‐state evoked potentials did not differ between groups. Hypersensitivity correlated positively with pain‐related fear and negatively with skin conductance level before LFS, despite the lack of group differences in skin conductance level. We did not find any sex differences in hypersensitivity.ConclusionsThese results do not confirm that high cognitive load or sex modulate hypersensitivity, but show associations with pain‐related fear and non‐pain‐related sympathetic arousal.SignificancePrevious research has mainly focused on cognitive load effects on the perception of acute painful stimuli. Yet this study extends our understanding by investigating cognitive load effects on the development of long‐lasting secondary hypersensitivity, a common aspect in numerous persistent pain conditions. As cognitive tasks are presented during a painful procedure inducing secondary hypersensitivity, we test the long‐lasting effects of cognitive load. Additionally, we used psychophysiological measurements to explored potential underlying mechanisms involving limited attentional resources and sympathetic arousal
Hybrid porous Ni(OH)2‐MnO2 nanosheets/plasma‐grafted MWCNTs for boosted supercapacitor performance
Authors: Chai Ai‐Wen , Wang Cheng‐Chien , Chen Chuh‐Yung 
Published: February 2023

AbstractThe utilization of nickel hydroxide and manganese dioxide solely as high‐performance supercapacitive materials is hindered by their low capacitance retention and electrical conductivity. As Ni(OH)2 and MnO2 give a synergistic effect, porous Ni(OH)2‐MnO2 nanosheets with a thickness of 9 nm are successfully grown on carbon fiber (CF) via a single‐step hydrothermal co‐deposition method. Multi‐walled carbon nanotubes (CNT) are grafted with maleic anhydride (MA) through plasma‐grafted process, followed by thiol‐ene reaction to synthesize CNT‐MA−S (CMS) to increase their aqueous dispersion behavior. The electrochemical properties of Ni(OH)2‐MnO2 are further enhanced by dip‐coating CMS on nanosheets. The composition and morphology of CMS and Ni(OH)2‐MnO2 nanosheets are characterized using scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), electron spectroscopy for chemical analysis (ESCA), transmission electron microscopy (TEM), thermogravimetric analyses (TGA), nuclear magnetic resonance (NMR), and Raman spectroscopy. The electrochemical characteristics of fabricated electrodes are analyzed using cyclic voltammetry and chronopotentiometry methods. CF−Ni(OH)2‐MnO2/CMS electrode is successfully synthesized without using any binder, exhibited ultrahigh specific capacitance (2049 F g−1 at a current density of 1 A g−1), and excellent capacitance retention (>80 %) at 2 A g−1 charge/discharge rate after 5000 cycles.
Analytically pricing exchange options with stochastic liquidity and regime switching
Authors: He Xin‐Jiang , Lin Sha 
Published: February 2023

AbstractWe investigate the valuation of exchange options when the market is affected by changing economic conditions as well as liquidity risks. The volatility and expected returns of both stocks are assumed to be controlled by a continuous‐time Markov chain to reflect the effects of varying economic conditions, and a liquidity discounting factor is employed to capture the impact of market liquidity on stock prices. Once the model has been established, we construct a risk‐neutral measure with the use of regime‐switching Esscher transform, and the characteristic function is then derived in an analytical form, so that a closed‐form formula for exchange options can be presented. We further analyze the effects of the two considered factors on exchange option prices numerically.
The trend of change in cervical tumor size and time to death of hospitalized patients in northwestern Ethiopia during 2018–2022: Retrospective study design
Authors: Aguade Aragaw E. , Gashu Chalachew , Jegnaw Tigist 
Published: February 2023

AbstractBackground and AimsCervical cancer is the fourth most common cause of cancer‐related death in the world. The objective of this study was to determine factors that affect the longitudinal change of tumor size and the time to death of outpatMethodsA retrospective follow‐up study was carried out among 322 randomly selected patients with cervical cancer at the University of Gondar Referral Hospital from May 15, 2018 to May 15, 2022. Data were extracted from the patient's chart from all patients' data records. Kaplan–Meier estimator, log‐rank test, the Cox proportional‐hazard model, and the joint model for the two response variables simultaneously were used.ResultsAmong 322 outpatients with cervical cancer, 148 (46%) of them were human immunodeficiency virus (HIV) positive and 107 (33.3%) of them died. The results of joint and separate models show that there is an association between survival and the longitudinal data in the analysis; it indicates that there is a dependency between longitudinal terms of cervical tumor size and time‐to‐death events. A unit centimeter square rise in tumor size, corresponding to an exp(0.8502) = 2.34 times, significantly raised the mortality risk.ConclusionThe study showed that HIV, stage of cancer, treatment, weight, history of abortion, oral contraceptive use, smoking status, and visit time were statistically significant factors for the two outcomes jointly.ImplicationsAs a result, adequate health services and adequate resource allocations are critical for cervical cancer control and prevention programs. Therefore, the government should provide adequate funding and well‐trained health professionals to hospitals to sustain screening programs with appropriate coverage of cervical cancer patient treatments.
Support needs and experiences of young people living in families with mental illness
Authors: Budden Timothy , Hafizuddin Ahmad , Dimmock James A. , Law Kwok Hong , Furzer Bonnie J. , Jackson Ben 
Published: February 2023

AbstractIntroductionChildren and adolescents living in families affected by mental illness are at elevated risk of developing mental health problems. A range of interventions have been designed to help these young people; however, the effectiveness of these programs is, in some cases, mixed. Our aim was to understand in detail the support needs and experiences of a group of Australian children and adolescents living in families with mental illness.MethodsOur study is a qualitative in nature. In 2020−2021, we interviewed 25 Australian young people (Mage = 13.60, SD = 2.26, 20 females and 5 males) living with family members affected by mental illness to understand their (the young people's) experiences, and to identify the types of support that these young people considered important or effective. We conducted reflexive thematic analyses of interview data, underpinned by interpretivist assumptions.ResultsWe identified seven themes within two higher‐order categories reflecting our aims to understand (1) lived experiences within families affected by mental illness (i.e., increased responsibilities, missing out, and stigmatization), and (2) support experiences, needs, and preferences (i.e., respite, shared experiences with like‐minded others, education, and flexibility).ConclusionsOur findings hold substantial practical value by informing services, interventions, and conversations that better support young people living in families affected by mental illness.
Revisiting the effect of growing up in a recession on attitudes towards redistribution
Authors: Bietenbeck Jan , Thiemann Petra 
Published: February 2023

SummaryGiuliano and Spilimbergo (2014) show that individuals who experienced a recession when young are more likely to favor redistribution in the short and long run. We revisit their analysis in three ways. First, we conduct a narrow replication in the General Social Survey and the World Values Survey; we successfully replicate the original results for outcomes that directly measure preferences for redistribution, but the results for other outcomes are less clear‐cut. Second, adding recent survey waves yields results similar to the narrow replication. Third, a wide replication in a different dataset (International Social Survey Programme) corroborates the original results.
Catalyst‐free, one‐pot three‐component synthesis of N,3‐diphenybenzo[d]imidazo[2,1‐b]thiazoles and oxybis(1‐phenyl‐2‐(phenylamino)ethanones)
Authors: Hajipour Mina , Mehrabi Hossein 
Published: February 2023

AbstractThe present work, highlights a highly effective unique procedure for the synthesis of N,3‐diphenybenzo[d]imidazo[2,1‐b]thiazoles and oxybis(1‐phenyl‐2‐(phenylamino)ethanones) via the one‐pot three‐component reaction between aryl glyoxal, aryl amine, and 2‐aminobenzothiazole under catalyst‐free conditions. The present mild and green method uses EtOH without catalyst at reflux conditions. No catalyst with high yields, availability of the starting materials, operational simplicity, cleaner reaction profile, no harmful byproducts, and the isolated products in pure form are the advantages of this protocol. Structures of all the freshly synthesized products have been deduced by their FT‐IR, 1H‐NMR, 13C‐NMR, and elemental analysis.
Risk‐based versus universal PrEP delivery during pregnancy: a cluster randomized trial in Western Kenya from 2018 to 2019
Authors: Kinuthia John , Dettinger Julia C. , Stern Joshua , Ngumbau Nancy , Ochieng Ben , Gómez Laurén , Abuna Felix , Watoyi Salphine , Marwa Mary , Odinga Daniel , Wagner Anjuli D. , Richardson Barbra A. , Pintye Jillian , Baeten Jared M. , John‐Stewart Grace 
Published: February 2023

AbstractIntroductionIntegrating pre‐exposure prophylaxis (PrEP) delivery for pregnant and postpartum women within maternal and child health (MCH) clinics is feasible and acceptable. It is unknown whether a risk‐guided model would facilitate appropriate PrEP use among MCH attendees better than universally offering PrEP.MethodsThe PrEP Implementation for Mothers in Antenatal Care (PrIMA) study was a cluster randomized trial to assess two models for PrEP delivery among pregnant women seeking routine MCH care at 20 public clinics in Kenya between January 2018 and July 2019 (NCT03070600). In the Universal arm, all participants received PrEP counselling and self‐selected whether to initiate PrEP. In the Targeted arm, participants underwent an HIV risk assessment, including an objective risk‐scoring tool and an offer of HIV self‐tests for at‐home partner testing; those determined to be at high risk received a PrEP offer. Participants were followed through 9 months postpartum. Primary outcomes included incident HIV and appropriate PrEP use (defined as PrEP uptake among those at high risk and no PrEP uptake for those not at risk). Outcomes were compared using intention‐to‐treat analyses, adjusting for baseline HIV risk and marital status.ResultsAmong 4447 women enrolled, the median age was 24.0 years (interquartile range [IQR]: 20.9, 28.3), and most were married (84.8%). The median gestational age at enrolment was 24 weeks (IQR: 20, 30). Women in the Targeted arm were more likely to be at high risk for HIV acquisition at baseline (51.6% vs. 33.3%). During 4638 person‐years (p‐yr) of follow‐up, there were 16 maternal HIV infections with no difference in maternal HIV incidence between arms: 0.31/100 p‐yr (95% CI: 0.15, 0.65) Targeted and 0.38/100p‐yr (95% CI: 0.20, 0.73) Universal (adjusted relative risk [aRR]: 0.85 [CI: 0.28, 2.55]). There was no significant difference in the frequency of appropriate PrEP use between the arms (68.2% vs. 59.1% in Targeted vs. Universal, respectively) (aRR: 1.03 [CI: 0.96, 1.10]).ConclusionsGiven comparable maternal HIV incidence and PrEP uptake in Universal and Targeted approaches, and the simplicity that universal PrEP offers, our findings suggest that universal PrEP counselling is optimal for integrating PrEP in MCH systems.
Sex differences in atrial fibrillation ablation in‐hospital outcomes from the National Inpatient Sample database 2016–2019
Authors: Shrestha Biraj , Fraga Julian Diaz , Poudel Bidhya , Donato Anthony 
Published: February 2023

AbstractBackgroundResearch has shown mixed results when comparing in‐hospital complications following atrial fibrillation ablation in women compared to men.ObjectivesTo better quantify sex differences and in‐hospital outcomes in atrial fibrillation ablation procedures and identify factors associated with poorer outcomes.MethodsWe queried the NIS database from 2016 to 2019 for hospitalizations with a primary diagnosis of atrial fibrillation ablation and excluded patients with any other arrhythmias, ICD/pacemaker placement. We assessed demographics, in‐hospital mortality, and complications of women compared to men.ResultsAdmissions for atrial fibrillation were more common in females than males (849 050 vs. 815 665; p < .001). However, females were less likely to receive ablation (1.65% vs. 2.71%, OR: 0.60; 95% confidence interval: 0.57–0.64, p < .001), which persisted after adjusting for cardiomyopathy (adjusted OR: 0.61; 95% confidence interval: 0.58–0.65, p < .001). The primary outcome of in‐hospital mortality was not statistically different in univariate analysis (0.39% vs. 0.36%, OR: 1.09, 95% CI: 0.44–2.72, p = .84), finding that did not change when adjusted for comorbidities (adjusted OR: 0.94, 95% CI: 0.36–2.49). The complication rate in hospitalized patients following ablation was 8.08%. The total unadjusted complication rate was higher for females than males (9.58% vs. 7.09%, p = .001); however, it was not significant when adjusted for risks (adjusted OR: 1.23, 95% CI: 0.99–1.53, p = .06).ConclusionFemale sex is not associated with increased complications or death in a real‐world study of catheter ablation when results are adjusted for risks. However, females admitted with atrial fibrillation receive ablation less often than males during hospital admission.
Why do researchers co‐author evidence syntheses with librarians? A mixed‐methods study
Authors: Logan Judith 
Published: February 2023

AbstractLibrarians and information specialists are experts in designing comprehensive literature searches, such as those needed for Evidence Syntheses (ES). The contributions of these professionals to ES research teams have several documented benefits, especially when they collaborate on the project. However, librarian co‐authorship is relatively rare. This study explores researcher motivations for working with librarians at the co‐author level through a mixed methods design. Interviews with researchers identified 20 potential motivations that were then tested through an online questionnaire sent to authors of recently published ES. Consistent with previous findings, most respondents did not have a librarian co‐author on their ES, though 16% acknowledged one in their manuscript and 10% consulted one but did not document the contribution. Search expertise was the most common motivation both to and not to co‐author with librarians. Those that had or were interested in co‐authoring stated that they wanted the librarians' search expertise, while those who had not or were not interested stated that they already had the necessary search expertise. Researchers who were motivated by methodological expertise and availability were more likely to have co‐authored their ES with a librarian. No motivations were negatively associated with librarian co‐authorship. These findings provide an overview of the motivations that influence researchers to bring a librarian into an ES investigatory team. More research is needed to substantiate the validity of these motivations.