bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transient Neonatal Myasthenia Gravis: A Case Report
Authors: Ristovska Sanja , Stomnaroska Orhideja , Dimitrioska Renata 
Published: July 2023

Abstract
Transient neonatal myasthenia gravis (TNMG) is a neuromuscular disorder that occurs in infants born from mothers with myasthenia gravis (MG) due to transplacental transfer of antibodies against the acetylcholine receptor. TNMG is a rare form occurring in 10-15% of infants born from mothers with MG.
We present a case of a newborn with TNMG with generalized hypotonia and respiratory distress. The newborn shows symptoms of hypotonia, weakened reflexes, poor crying, difficult sucking and potentiated tachydyspnea after 24 hours of birth and needs of assisted mechanical ventilation. Based on the mother’s positive history of MG and the high titer of mother’s (8.43nmol/l) and newborn’s (9.088nmol/l) anti-AChR antibodies, TNMG was diagnosed. The baby was treated with assisted mechanical ventilation and neostig-mine until the anti-AChR antibody titer was negative. Adequate management of the newborn resulted in a positive outcome and evident withdrawal of the symptoms.
Although TNMG is one of the rare neuromuscular disorders in newborns that can be treated, a multidisciplinary approach in the management of pregnant women with MG and newborns through timely diagnosis and early appropriate treatment, results in successful resolution of this condition.
Peripheral Insulin Edema and Pericardial Effusion in a 12-Year-Old Newly Diagnosed Girl with Type 1 Diabetes
Authors: Janchevska Aleksandra , Jovanovska Valentina , Jordanova Olivera , Beqiri-Jashari Ardiana , Krstevska-Konstantinova Marina , Tasic Velibor , Gucev Zoran S. 
Published: July 2023

Abstract

Introduction: Insulin induced edema (IIE) is a rare condition, usually found in newly diagnosed diabetes patients, either after insulin treatment initiation or after dose increment. It is a self-limited process, rarely associated with serosal effusions. Teenage girls with type 1 diabetes (T1DM) are most commonly affected.

Patient and Methods: A 12-year-old girl was diagnosed with ketoacidosis (DKA). Seven days after initiation of the insulin treatment, at a stable total daily dose of insulin (TDDI) of 0.55 IU/kg, she came with two kilograms weight gain in only two days and edema of the feet and calves. Ultrasound of the heart found a 7 mm pericardial effusion. The diagnostic workout included clinical examination, biochemical, hormonal, allergen analyses and imaging which excluded other known causes of swelling. Conclusions: We describe an adolescent girl with newly diagnosed T1DM and a rare association of peripheral insulin-induced edema and pericardial effusion. Short-term diuretic treatment and salt restriction resolved this rare complication of insulin treatment.
Uncommon Cases of Venous Thromboembolism
Authors: Bosevski Marijan , Bojovski Ivica , Vuchinikj Aleksandra Gulevska , Anguseva Tanja , Taleski Jane , Dimitrovska Biljana , Sheshoska Hristina Chamovska , Taneska Natasa , Jovchevska Simona , Konjanovski Tomi , Zhaku Vegim , Jovanoski Mario. , Ilieva Anastasija , Tsonev Svetlin , Petkoska Danica , Jordanova Savetka Paljoskovska 
Published: July 2023

Abstract
There is a growing incidence of new cases of venous thromboembolismworldwide.Some of these patients do have a predisposition to the development of thrombosis, some of them do however have various risk factors associated with this event, but few of them have unrecognized etiology. This paper aimsto describe different scenarios of venous thromboembolism.
Role of Cardiac Magnetic Resonance in Diagnosis and Treatment of Ball Thrombus in Left Atrium – Trust But Verify! – Case Report
Authors: Trajcheski Ted , Brovina Lulzim , Zafirova Biljana , Josimovski Saso 
Published: July 2023

Abstract
Male patient with left atrial cardiac mass was in need of a quick diagnosis for individualized and effective treatment. Transthoracic echocardiography showed presence of а giant left atrial cardiac mass with atypical location for thrombus. Cardiac Magnetic Resonance (CMR) Imaging was performed for histological discrimination, and showed a large cardiac mass wall attached in the left atrium, homogeneous, with diameter of 3.4cm x 3.2cm. Late Gadolinium Enhancement sequences revealed black avascular tissue without signal, confirming the characterization of a thrombus.
The patient refused hospital initiation of low molecular weight heparin treatment and started treatment with Rivaroxaban. Six weeks later he presented with NYHA class II, almost complete dissolving of the thrombus on CMR scan. Seven months from the initial CMR scan, echocardiography screen was done showing complete absence of the left atrial mass. With this case report we have demonstrated the significance of the CMR as one step further in the precise diagnostics of cardiac masses, solving critical clinical dilemma.
Web Platform for Gathering and Analyzing Data from the Neurogame Mobile Application
Authors: Loleska Sofija , Pop-Jordanova Nada 
Published: July 2023

Abstract
Today’s cell phones are now smartphones, providing a wide range of possibilities for their use, much more than just simple phones. The custom application for the Android operating system, based on an open-source platform for mobile devices is intended for the examination of cognitive functions: attention, concentration and fine motor skills in children of different age groups. The Neurogame application for mobile devices and web platform development is used for retrieving and analyzing mobile application data, providing relevant indicators for the executive functions of the respondents.

Material and methods: The research included 50 children with the developmental disorders ADHD and dyslexia (study group) and 50 healthy children (control group), randomly selected, evenly represented by gender and age. Using the application, we determine attention, concentration and motor skills (reaction speed) as part of the executive functions of the respondents.
The web platform has the purpose of gathering and processing the data from the mobile application, as well as their automatic visual representation.

Results: The ANOVA test showed that there are no gender differences in all the studied groups. A statistical correlation analysis showed that age does not affect the results in healthy school children. In children with dyslexia, age affects positively for total hits and negatively for total misses. In children with ADHD, there is a positive correlation with age for all variables except total hits (t H). Student’s T-test showed that there were significant differences for the variables’ total hits (t H) and total reaction time (t h) in milliseconds between healthy school children and children with dyslexia. Additionally, Student’s t-test indicated that there were significant differences for the variables’ total tries (t T) and total hits (t H) between healthy school children and children with ADHD. Finally, Student’s t-test indicated that there were significant differences for the variable total tries (t T) between children with dyslexia and children with ADHD. Multiple Regression Results showed a significant difference between healthy school children, children with ADHD and children with dyslexia for all variables (total tries (t T), total hits (t H), total misses (t M) and total reaction time in milliseconds (t h)).

Conclusion: The Neurogame application provides a opportunity to assess the motor skills and concentration level, as well as the focus of the target population by measuring the total number of tries, the total number of hits, the total number of misses and the reaction time expressed in milliseconds which are defined as monitoring variables. The development of the web platform and the connection to the application enabled easier access and distribution of the analyzed results to the stakeholders (parents, teachers, therapists or health professionals) in order to further treat the ascertained condition.
Sustaining a Mars Colony through Integration of Single-Cell Oil in Biological Life Support Systems
Authors: Spalvins Kriss , Kusnere Zane , Raita Svetlana 
Published: July 2023

Abstract
As humanity sets its sights on establishing a sustainable and prosperous colony on Mars, the main challenges to be overcome are ensuring a reliable and nutritious food supply for settlers, feedstock for 3D printing, fuel and pharmaceuticals. While various solutions for production of essential products on Mars have been proposed, there is growing interest in the use of microorganisms as the main production units. This scientific review article proposes a novel concept of using single cell oil (SCO) as a versatile feedstock for various applications in a bioregenerative life support system (BLSS) for space missions. The authors suggest using outputs from autotrophic systems, such as cyanobacteria biomass and oxygen, to cultivate SCO-producing microorganisms from the class Labyrinthulomycetes. The produced SCO can be used for food, fuel, 3D printing materials, and pharmaceuticals. This approach can potentially reduce the importance of carbohydrates in space foods, offering various benefits, including a reduction in food weight, simpler, lightweight, more compact bioreactors, launch cost reduction, potentially improved mental and cognitive performance, and reduced fatigue for the crew. The authors also suggest using SCO as the feedstock for the production of 3D printable filaments and resins and as a supplementary fuel source for space colonies. While the concept is hypothetical, the theoretical foundation is solid, and this approach could potentially become an important element required for the establishment of a successful Mars colony.
Individual Adaptability to Work: Scale Validation on the Romanian Population
Authors: Botezat Elena Aurelia , Crisan Daniela , Fotea Silvia Liana , Fotea Ioan Stefan 
Published: July 2023

Abstract
This study aimed to validate the I-ADAPT scale to assess the individual adaptability to work within the Romanian population. Both a pilot study and a main study were conducted on a total sample of 966 Romanians. Following the application of standard scale validation procedures, the results of our study indicated that the I-ADAPT measure of work adaptability has good psychometric properties on the Romanian population. Our findings provide evidence that I-ADAPT continues to explain the unique variance in adaptability to work even if work patterns in the Covid-19 pandemic context moved more and more from a traditional to a virtual work environment. ROa I-ADAPT measure has excellent properties concerning convergent, discriminant, and criterion-related validity. One main finding was that the “Physical” dimension of adaptability to work had no empirical support in the Romanian population. Moreover, our results indicate that the “interpersonal adaptability” and the “cultural adaptability” dimensions cannot be empirically separated in the Romanian population. To our knowledge, this is the first validated instrument that can be used to assess the individual adaptability of Romanians in the context of work. Our study is relevant for decision-makers in Romania and such actors in other EU-member countries where Romanians represent the largest group of working-age EU citizens.
Integration of Digital Technology in Enterprises
Authors: Ionescu Luiza , Founanou Mathurin , Toma Maria 
Published: July 2023

Abstract
This study analyzes the main indicators regarding integrating digital technology in enterprises, in the context of sustainable digital transformation in the European Union (EU). The purpose of this analysis is to group indicators into three levels of importance. Thus, using the semaphore technique, the indicators will be delimited by three colors: green, yellow, and red. Depending on the three colors, future measures will be taken and strategies will be established regarding the indicators thus delimited. This research methodology is based on comparative analysis and case studies.
Mathematical Modelling Designed for Monitoring Traceability and Quality Statistical Control in Romanian SMEs
Authors: Mircea Raul Bogdan , Lile Ramona , Tucu Dumitru , Gal Lucian , Babanatsas Theoharis 
Published: July 2023

Abstract
The paper presents a confirmed case of a factory in the west of the country, where the stochastic modeling generated by the software was implemented into SAP. This project was born out of necessity. Thus, to keep the processes under control and contribute to their improvement, they must be monitored, measured and analyzed regularly. As long as the main process indicators are monitored, the need to take corrective or improvement actions (whether reorganization or additional investment is needed) can be detected in time so that the company’s performance does not decrease to the level where the customer is no longer satisfied of the quality of the delivered products or too high non-quality costs appear that will no longer allow the achievement of the established objectives (Besterfield, D. H. et al., 2011). The program is presented in detail, starting with the introduction of collected data, the processing and generation of indicator graphs. The indicators have high accuracy and greatly help in making decisions. Finally, an improvement in production can be observed following the use of this software (Bourne, M., & Bourne, P., 2012). The purpose of our study is to create a stochastic mathematical model. Starting from a specific condition in SMEs from Romania, this study presents possibilities of innovation in operational structures specialized in quality monitoring, traceability and statistical control based on integrated modules in general software. The innovation process is based on data collected and monitored in real-time from the manufacturing process in conditions where the system ensures quality compliance at all stages of production. Through its modern functionalities, blockages are eliminated, waste of time is avoided, materials and money are saved, and it strengthens the business partnerships and the company’s position in the market. Results regarding particular implementations are preserved. Data is collected and monitored in real-time and the system ensures quality compliance at all stages of production.
From Digitization to Artificial Intelligence in External Public Audit
Authors: Lazăr Pleşa Teodora , Popescu Constanța , Pleşa Iliodor Tiberiu 
Published: July 2023

Abstract
Digitization is one of the main concerns in contemporary society, this phenomenon being accentuated with the emergence of the COVID-19 pandemic, which forced everyone to use technology under the conditions imposed by the new reality based on social distancing. The paper aims to analyze the use of digitization at the level of supreme audit institutions, the transition to artificial intelligence, as well as its impact on performance management, both in terms of performance at the level of these institutions and in terms of the public sector, in its whole. At the same time, the paper aims to pinpoint a series of tools based on artificial intelligence that could be used in the external public audit and, in particular, with regard to the audit of public procurement, given the importance of the funds allocated to the area of public procurement.
The Impact of Monetary Policy on Bank Lending in Romania in the Context of Covid-19
Authors: Drăgoi Violeta Elena , Preda Larisa Elena , Dincă Diaconu Lavinia Roxana , Dincu Ana-Mariana 
Published: July 2023

Abstract
This study explores the impact of the monetary policy of the National Bank of Romania, with its instruments and objectives during the Covid-19 pandemic, on the banks lending in Romania, considering the data provided by the NBR for the last 6 years. Overall, our findings confirm that the increasing bank lending channel for global monetary policy was active during the pandemic crisis.
Pollen Viability and Germination Levels with Amount of Pollen Production of Some Important Olive Cultivars in Türkiye
Authors: Dölek Gencer Cansu , Özkaya Mücahit Taha , Eti Sinan , Karabıyık Şenay , Taskin Madrigal Fletcher Neslihan 
Published: July 2023

This research was carried out to determine the pollination abilities of Domat, Gemlik and Sarı Ulak olive cultivars. Pollen viability rate, germination rate and amount of pollen production were examined during the periods when 25%, 50% and 75% of the flowers were opened. According to the results obtained from three years’ experimental study, the highest percentages of pollen viability were found in Gemlik (81.51%) and Domat (81.50%), whereas Sarı Ulak cultivar (77.41%) showed the lowest viability. In pollen germination percentages, the highest values on the basis of cultivars were determined 59.85% (Domat), 59.74% (Gemlik) and 52.12% (Sarı Ulak). The highest amount of pollen production in a flower was found in the Sarı Ulak cultivar (329,046) while it was followed by Domat (319,693) and Gemlik (306,385). Despite the high pollen production in Sarı Ulak cultivar, the pollen viability and germination rates were found to be low. In Gemlik and Domat cultivars, all values were obtained relatively near. In addition, it had been noted that the values related to pollen viability, germination and production amount were higher during 50% and 75% flowering periods than 25%.
Frequency Domain Analysis of Load Frequency Control Using PIDTune Model Standard
Authors: Laksono Heru Dibyo , ‘Aisya Rohadatul 
Published: July 2023

The load frequency control system aims to regulate the frequency in the electric power system at a normal value with a predetermined tolerance limit. In practice, the load frequency control system does not always operate optimally, therefore a controller is needed to be added to the load frequency control system. The controller designed is a variation of the combination of Proportional-Integral-Differential (PID) controllers with the standard model PIDTune method consisting of proportional (P) controller, proportional integral (PI) controller, proportional differential (PD) controller, Proportional Integral Differential (PID) controller, Proportional Differential controller with first-order filter on differential section (PDF), and Proportional Integral Differential controller with first-order filter on differential section (PIDF). This study is aiming to carry out simulation and analysis in the frequency domain and then analyze the robustness of the reheat type power frequency control system and then design a PID controller for the reheat type power frequency control system in basic configuration, filter configuration, feedback configuration, feedforward configuration, and cascade configuration using PIDtune Model Standard on Matlab software. From the results of simulation and analysis, the controller that complies the design criteria and can make the reheat type of load frequency control system work optimally based on frequency domain analysis and robustness analysis is a proportional-integral (PI) controller in a feedback configuration with gain margin (Kg) equals to 38.11 dB, phase margin equals to 59.6°, infinity bandwidth, peak resonance value (Mr) equals to 1.19, maximum sensitivity peak value (MS) equals to 1.24, and complementary maximum sensitivity peak value (MT) equals to 1,17.
Treatment outcome of appendicitis in Azare
Authors: Bwala Kefas John , Giade Abdullahi Sani , Yusuf Stephen , Adamu Sani , Umar Aminu Muhammed , Busayo Jatto Kabir , Okoruwa Oaikhena John 
Published: July 2023

Objectives:
Appendicitis is and has remained one of the most common abdominal surgical emergencies the world over. Its procedure and appendectomy is also a very common and regularly done surgical procedure and, thus, a very important disease to describe in totality. Hence, we set out to describe the pattern of presentation and management outcome of this condition in our environment.

Materials and Methods:
Data were collected retrospectively of all patients with the clinical diagnosis of appendicitis during the study period and analyzed.

Results:
A total of 62 patients had a clinical diagnosis of appendicitis over the period under review. M: F was 1:1.1. Age ranged from 3 years to 47 years with a mean of 21.50 ± 10.07. All (100%) patients presented with right iliac fossa pain. Other symptoms were anorexia (45.2%), nausea (61.3%), and vomiting (40.3%). All (100%) of patients went on to have an appendectomy. Twelve (19.40%) patients had surgical site infection and 2 (3.20%) developed enterocutaneous fistula. Duration of hospital stay ranged from 1 to 30 days. One patient who had uncontrolled diabetes mellitus died giving a mortality rate of 1.6.

Conclusion:
Typical clinical features of acute appendicitis were lower abdominal quadrant pain associated with nausea, anorexia, and vomiting. It goes without saying that diagnosis can still be made comfortably on clinical grounds and treatment outcome is generally good.
Herbal Products Sold in Sikkim Himalaya Region – India: A Mini Survey
Authors: Bhutia Karma Namgyal , Basnett Dhan Kumari , Bhattarai Abhishek , Bhutia Sonam 
Published: July 2023

Objective:
The present survey aimed to interact with the vendors, analyze, examine, and document the herbal medicinal products sold in retail stores, pharmacies, AYUSH stores, generally closed and open markets in the local area of Sikkim, mainly rural towns – Gangtok, Ranipool, Singtam, and Rangpo. It was a first of its kind study on the selected topic in Sikkim – India.

Material and Methods:
The methodology followed during the survey was a cross-sectional study, open ended semi-structured questionnaire, and survey data collection tools were employed; descriptive and inferential statistics were done.

Results:
The results were summarized in the different tables. From, it was found that old age (46+) uses most of the herbal products (66.6%), adult (20–45 years) uses 42.6% of herbal products, adolescent (13–19) uses 16.6%, and child (1–12) uses 14.5%. Females use more herbal products than males at 57%, and males at 43%. It was found that a large number of herbal products in Sikkim are manufactured outside Sikkim (98%) and 2% of the products were manufactured in Sikkim. Herbal product packaging is mostly secondary (66%), followed by primary (28%) and tertiary packaging (6%). It was found that a large number of solid dosage (47%) form of herbal products is available in the market followed by liquid dosage form (38%). According to brand wise or company wise, Patanjali (41%) products accounted for a big share on the market followed by Baidyanath (19%), other brands (15%), AYUSH (11%), Himalaya (8%), and Dabur (6%). Based on diseases treated, digestion, and metabolism (21%) followed by bone and joint pain (17%), diabetes mellitus (14%), cough and cold (12%), piles (11%), hypertension (7%), thyroid (3%), and other other common diseases categories represents about 15%. Highlights the situation after the COVID-19 pandemic indicating drastic increases in market value (in Lakhs) and the sale of herbal products in Sikkim.

Conclusion:
The data highlighted above were the first of its kind in a study done in Sikkim – India; no data were available in any scientific repositories to date.