bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does physical fitness affect cognitive functions differently across adulthood? An advantage of being older
Authors: Gajewski Patrick D. , Golka Klaus , Hengstler Jan G. , Kadhum Thura , Digutsch Jan , Genç Erhan , Wascher Edmund , Getzmann Stephan 
Published: June 2023

IntroductionThere is a large interindividual variability in cognitive functioning with increasing age due to biological and lifestyle factors. One of the most important lifestyle factors is the level of physical fitness (PF). The link between PF and brain activity is widely accepted but the specificity of cognitive functions affected by physical fitness across the adult lifespan is less understood. The present study aims to clarify whether PF is basically related to cognition and general intelligence in healthy adults, and whether higher levels of PF are associated with better performance in the same or different cognitive functions at different ages.MethodsA sample of 490 participants (20–70 years) was analyzed to examine this relationship. Later, the sample was split half into the young to middle-aged group (YM; 20–45 years; n = 254), and the middleaged to older group (MO; 46–70 years; n = 236). PF was measured by a quotient of maximum power in a bicycle ergometry test PWC-130 divided by body weight (W/kg), which was supported by a self-reported level of PF. Cognitive performance was evaluated by standardized neuropsychological test batteries.ResultsRegression models showed a relationship between PF and general intelligence (g-factor) and its subcomponents extracted using structural equation modeling (SEM) in the entire sample. This association was moderated by age, which also moderated some specific cognitive domains such as attention, logical reasoning, and interference processing. After splitting the sample into two age groups, a significant relationship was found between cognitive status, as assessed by the Mini Mental State Examination (MMSE), and PF in both age groups. However, apart from cognitive failures in daily life (CFQ), no other association between PF and specific cognitive functions was found in the YM group. In contrast, several positive associations were observed in the MO group, such as with selective attention, verbal memory, working memory, logical reasoning, and interference processing.DiscussionThese findings show that middle-aged to older adults benefit more from PF than younger to middle-aged adults. The results are discussed in terms of the neurobiological mechanisms underlying the cognitive effects of PF across the lifespan.Clinical trial registration:https://clinicaltrials.gov/ct2/show/NCT05155397, identifier NCT05155397.
Factors influencing acceptance and trust of chatbots in juvenile offenders’ risk assessment training
Authors: Raiche Ann-Pierre , Dauphinais Léanne , Duval Manon , De Luca Gino , Rivest-Hénault David , Vaughan Thomas , Proulx Catherine , Guay Jean-Pierre 
Published: June 2023

IntroductionResearch has identified simulation-based training with chatbots and virtual avatars as an effective educational strategy in some domains, such as medicine and mental health disciplines. Several studies on interactive systems have also suggested that user experience is decisive for adoption. As interest increases, it becomes important to examine the factors influencing user acceptance and trust in simulation-based training systems, and to validate applicability to specific learning tasks. The aim of this research is twofold: (1) to examine the perceived acceptance and trust in a risk assessment training chatbot developed to help students assess risk and needs of juvenile offenders, and (2) to examine the factors influencing students’ perceptions of acceptance and trust.MethodsParticipants were 112 criminology students in an undergraduate course in a Canadian university. Participants were directed to use a custom-designed chatbot with a virtual 3D avatar for juvenile offenders’ risk assessment training, to complete online questionnaires and a risk assessment exercise.ResultsResults show satisfactory levels of acceptance and trust in the chatbot. Concerning acceptance, more than half appeared to be satisfied or very satisfied with the chatbot, while most participants appeared to be neutral or satisfied with the benevolence and credibility of the chatbot.DiscussionResults suggest that acceptance and trust do not only depend on the design of the chatbot software, but also on the characteristics of the user, and most prominently on self-efficacy, state anxiety, learning styles and neuroticism personality traits. As trust and acceptance play a vital role in determining technology success, these results are encouraging.
Social visual preference mediates the effect of cortical thickness on symptom severity in children with autism spectrum disorder
Authors: Chen Jierong , Wei Zhen , Xu Chuangyong , Peng Ziwen , Yang Junjie , Wan Guobin , Chen Bin , Gong Jianhua , Zhou Keying 
Published: June 2023

BackgroundEvidence suggests that there is a robust relationship between altered neuroanatomy and autistic symptoms in individuals with autism spectrum disorder (ASD). Social visual preference, which is regulated by specific brain regions, is also related to symptom severity. However, there were a few studies explored the potential relationships among brain structure, symptom severity, and social visual preference.MethodsThe current study investigated relationships among brain structure, social visual preference, and symptom severity in 43 children with ASD and 26 typically developing (TD) children (aged 2–6 years).ResultsSignificant differences were found in social visual preference and cortical morphometry between the two groups. Decreased percentage of fixation time in digital social images (%DSI) was negatively related to not only the thickness of the left fusiform gyrus (FG) and right insula, but also the Calibrated Severity Scores for the Autism Diagnostic Observation Schedule-Social Affect (ADOS-SA-CSS). Mediation analysis showed that %DSI partially mediated the relationship between neuroanatomical alterations (specifically, thickness of the left FG and right insula) and symptom severity.ConclusionThese findings offer initial evidence that atypical neuroanatomical alterations may not only result in direct effects on symptom severity but also lead to indirect effects on symptom severity through social visual preference. This finding enhances our understanding of the multiple neural mechanisms implicated in ASD.
Walking activity increases physical abilities and subjective health in people with seven different types of disabilities
Authors: Selanon Pattamon , Chuangchai Warawoot 
Published: June 2023

IntroductionPeople with disabilities have a great risk of physical inactivity, which causes several diseases, dependency, and long-term care. Walking helps to increase physical activity, which leads to better overall health and independence. However, less research attention has focused on walking for people with disabilities, and even fewer studies have been considered for different types of disabilities. The present study aimed to demonstrate how walking distance was associated with people with seven different types of disabilities— including visual, hearing, physical/mobility, intellectual, learning, autism, and emotional/behavioral disabilities—in terms of their physical abilities and subjective health.MethodsA total of 378 participants (aged 13–65) were gathered from seven national organizations in Thailand. A survey questionnaire on aspects of physical abilities (i.e., walking distance or manually rolling wheelchair distance; body balance; weightlifting; exercise duration and frequency); and subjective health (i.e., health status and satisfaction) was completed online by all participants.ResultsThe walking distance was partially positive and associated with exercise duration, weightlifting, exercise frequency, and health status (all p values &lt; 0.001), as well as body balance and health satisfaction (p = 0.001 and 0.004, respectively), after controlling for age, sex, and types of disability. This demonstrated that increasing the amount of distance walked could well lead to a more positive body and mind.DiscussionThe present study suggests that the possibility of having a walk and/or encouraging people with disabilities to walk for greater distances can have a significant impact on both their physical and subjective health outcomes.
Is sub-national healthcare social protection sufficient for protecting rare disease patients? the case of China
Authors: Xu Juan , Yu Mingren , Zhang Zhiguo , Gong Shiwei , Li Bingqin 
Published: June 2023

BackgroundFailing to provide social support to cover healthcare costs for rare diseases would lead to great financial distress for the patients and their families. People from countries without a well-developed health safety-net are particularly vulnerable. Existing literature on rare diseases in China focuses on the unmet needs for care of the patients and the difficulties of caregivers and physicians. Very few studies examine the state of social safety-net, the unresolved issues and whether the current localized arrangements are sufficient. This study aimed to gain in-depth knowledge of the current policy system and make sense of the local varieties, which would be essential for developing strategies for future policy changes.MethodsThis systematic policy review focuses on the provincial level policies on subsidizing the healthcare costs for people with rare diseases in China. The cut-off point for the policies was March 19, 2022. The researchers coded the healthcare cost reimbursement policies and identified the different provincial level models based on the usage of reimbursement components in each provinces reimbursement arrangements.Results257 documents were collected. Five provincial level models (Process I, II, III, IV and V) have been identified with the five components across the country: Basic Medical Insurance for Outpatient Special Diseases (OSD), Catastrophic Medical Insurance for Rare Diseases (CMIRD), Medical Assistance for Rare Diseases (MARD), Special Fund for Rare Diseases (SFRD) and Mutual Medical Fund (MMF). The local health safety-net in each region is a combination of one or more of the five processes. Regions vary greatly in their rare diseases coverage and reimbursement policies.ConclusionIn China, the provincial health authorities have developed some level of social protection for rare disease patients. However, there are still gaps regarding coverage and regional inequality; and there is room for a more integrated healthcare safety-net for people suffering from rare diseases at the national level.
Top of the podium, at what cost? injuries in female international elite climbers
Authors: Grønhaug G. , Joubert L. M. , Saeterbakken A. H. , Drum S. N. , Nelson M. C. 
Published: June 2023

ObjectivesCompetitive sport climbing has made its way to the Olympic stage. This prestige has brought about route setting and training alterations which presumably affect injury epidemiology. Most of the climbing injury literature contains male climbers and lacks high performing athletes. Studies with both female and male climbers, rarely included separate analyses for performance level or sex. Therefore, injury concerns for elite female competitive climbers are impossible to discern. A former study examined the prevalence of amenorrhea in elite international female climbers (n = 114) and reported that 53.5% had at least one injury in the past 12 months, but injury details were excluded. This study's aim was to report these injury details and their associations with BMI, menstrual status and eating disorders of the cohort.MethodsOnline survey was emailed to competitive female climbers recruited through the IFSC database between June and August 2021. Data was analyzed using Mann–Whitney U, χ2 and logistic regression.Results229 registered IFSC climbers opened the questionnaire and 114 (49.7%) provided valid responses. Respondents (mean ± SD; age = 22.9 ± 5 year) represented 30 different countries and more than half (53.5%, n = 61) reported an injury in the prior 12 months with the majority in shoulders (37.7%, n = 23) and fingers (34.4%, n = 21). Injury prevalence in climbers with amenorrhea was 55.6% (n = 10). BMI was not a significant predictor of injury risk (OR = 1.082, 95% CI: 0.89, 1.3; p = 0.440) while accounting for current ED over the past 12 months. However, the odds ratio for having an injury was doubled for those with an ED (OR = 2.129, 95% CI: 0.905, 5.010; p = 0.08).ConclusionWith over half reporting recent injuries (&lt;12 months) mostly to shoulders and fingers, development of new strategies for injury prevention in competitive female climbers are warranted. In addition, climbers with disordered eating behaviors and/or menstrual disturbances might be more prone to injury. More research in this population is required. Suitable screening to prevent these health issues and proper monitoring of these athletes are paramount to long-term athlete success.
Systematic Characterization of GATA Transcription Factors in Liriodendron chinense and Functional Validation in Abiotic Stresses
Authors: Hwarari Delight , Radani Yasmina , Guan Yuanlin , Chen Jinhui , Liming Yang 
Published: June 2023

The Liriodendron chinense in the Magnoliaceae family is an endangered tree species useful for its socio-economic and ecological benefits. Abiotic stresses (cold, heat, and drought stress), among other factors, affect its growth, development, and distribution. However, GATA transcription factors (TFs) respond to various abiotic stresses and play a significant role in plant acclimatization to abiotic stresses. To determine the function of GATA TFs in L. chinense, we investigated the GATA genes in the genome of L. chinense. In this study, a total of 18 GATA genes were identified, which were randomly distributed on 12 of the total 17 chromosomes. These GATA genes clustered together in four separate groups based on their phylogenetic relationships, gene structures, and domain conservation arrangements. Detailed interspecies phylogenetic analyses of the GATA gene family demonstrated a conservation of the GATAs and a probable diversification that prompted gene diversification in plant species. In addition, the LcGATA gene family was shown to be evolutionarily closer to that of O. sativa, giving an insight into the possible LcGATA gene functions. Investigations of LcGATA gene duplication showed four gene duplicate pairs by the segmental duplication event, and these genes were a result of strong purified selection. Analysis of the cis-regulatory elements demonstrated a significant representation of the abiotic stress elements in the promoter regions of the LcGATA genes. Additional gene expressions through transcriptome and qPCR analyses revealed a significant upregulation of LcGATA17, and LcGATA18 in various stresses, including heat, cold, and drought stress in all time points analyzed. We concluded that the LcGATA genes play a pivotal role in regulating abiotic stress in L. chinense. In summary, our results provide new insights into understanding of the LcGATA gene family and their regulatory functions during abiotic stresses.
Retrospectıve Analysis Of Risk Factors In The Development Of Biliary Fistula After Liver Hydatid Cyst Surgery
Authors: KARA Salih , KORKUT Ercan , AKSUNGUR Nurhak , ALTUNDAŞ Necip , ÖZTÜRK Gürkan 
Published: June 2023

Abstract
Background: Cystic echinococcosis (CE) of the liver is a parasitic disease caused by the larvae of Echinococcus granulosus. Although CE is a disease with benign characteristics, its morbidity is high in the presence of complicated cysts. The most important complications are fistulization of the biliary tract and intraperitoneal cyst ruptures
Material Methods: Patients who underwent surgery for CE in Atatürk University Research Hospital between 2011 and 2021 were analyzed retrospectively. Demographic information, CE localization, cyst size, CE classification, surgical techniques and hospitalization time of all operated patients were recorded. The effect of all data types on the categorical variable was analyzed using binary logistic regression.
Results: Of the patients, 299 (60.2%) were female, and 198 (39.8%) were male. The mean age was 41 ± 15.48 and 41 ± 15.36 years in the group with and without bile fistula, respectively. We found a significant difference in mean cyst sizes between the two groups. Cyst location and cyst type according to WHO classification had a statistically significant effect on the cysto biliary communication (p: 0.00, p: 0.00, respectively. Analysis by cyst types showed that CE 1, CE2, CE3A, and CE3B cysts were statistically significantly effective on biliary fistula formation. CE 1 type cysts were more effective than other cyst types. CE 2, CE3A, and CE 3B cysts were less effective than CE1
Conclusion: The risk of bile leakage is higher in hepatic hydatid cysts located in the left lobe and in CE1 cysts. The incidence of bile leakage increases in large cysts.
Kinematik Analiz İle Belirlenen İn-Toeing ve Out-Toeing Adım Açısı Bozukluklarının Bazı Anaerobik Egzersiz Parametrelerine Etkisi
Authors: ŞERARE Serdar , ŞENEL Ömer , HAZAR Serkan , PAZARCI Ozhan , AKYOL Betül 
Published: June 2023

Giriş ve Amaç: Popülasyonun % 40’ında patolojik olmayan ayak deformitesi görülmektir ve birçok sporcuda rastlanması muhtemeldir. Bu çalışmanın amacı içe dönük İn-Toeing (TOE-İN) ve dışa dönük Out-Toeing (TOE-OUT) ayak adım açısı bozukluklarının bazı anaerobik egzersiz parametrelerine etkilerini tespit etmektir.
Gereç ve Yöntemler: Kadın ve erkek denek gurupları kinematik analiz ve kesitsel tarama yöntemi ile belirlenerek guruplara ayrılan, 18-25 yaş aralığında, lisanlı spor yaşantısı bulunmayan bireylerden oluşmaktadır. Bağımsız ayak guruplarına Anaerobik Güç Testlerinden olan Dikey Sıçrama Testi (DST), Çift Ayak Yatay Sıçrama Testi (YST) ve Tek Ayak Penta (beşli) Sıçrama Testi (PST) uygulandı. Bağımsız ikiden fazla grubun parametrik test ile karşılaştırması ANOVA varyans analizi ve Tukey (postoc) testleri ile gerçekleştirildi.
Bulgular: DST'inde erkek gurupları arasında anlamlı farklılık bulunmazken kadın TOE-OUT'un DST değeri TOE-İN göre anlamlı bulunmuştur (p
Menelusuri Jejak Nilai Iman Kristen dalam Kepemimpinan Tallu Lalikan di Lembang Limbong Sangpolo
Authors: Devisa Orin , Sumule Linus 
Published: June 2023

Abstract: Community life is strongly influenced by the order and values ​​prevailing in that society. The value itself is the biggest contribution to the growth and development of society. In Lembang, Sangpolo uses Tallu Lalikan. Tallu Lalikan itself is a stone kitchen stove, numbering three. Tallu Lalikan in this context is not about religious views but rather on the organizational structure of society, namely Religion or Aluk, Adat or ada' and Government. The role of Tallu Lalikan itself is how the collaboration of Christian faith and community growth is played by certain figures. In this study, a qualitative approach was used with library research and field research data collection techniques, namely data observation and interviews. The aim of this research is to find out the traces of the value of the Christian Faith in the Tallu Lalikan leadership in Lembang Limbong Sangpolo. Through this research it is hoped that it will provide results regarding the positive influence of the value of the Christian faith in leadership on the life order of the Tallu Lalikan Community in Lembang Limbong Sangpolo. Tallu Lalikan leadership will build good relationships and will produce quality social life. Keywords: Christian faith, Leadership, Governance and Tallu Lalikan

This work is licensed under a Creative Commons Attribution- -ShareAlike 4.0 International (CC BY-SA 4.0)

Abstrak: Kehidupan bermasyarakat sangat dipengaruhi oleh tatanan dan nilai-nilai yang berlaku dalam Masyarakat tersebut. Nilai itu sendiri yang menjadi sumbangsi terbesar dalam pertumbuhan dan perkembangan Masyarakat. Di Lembang Sangpolo diterapkan Tallu Lalikan. Tallu Lalikan itu sendiri adalah batu tungku dapur yang berjumlah tiga buah. Tallu Lalikan dalam konteks ini bukanlah mengenai pandangan religius tetapi lebih kepada tatanan organisasi Masyarakat, yaitu Agama atau Aluk, Adat atau ada’ dan Pemerintahan. Peranan dari Tallu Lalikan sendiri adalah bagaimana Kolaborasi iman Kristen dan pertumbuhan Masyarakat yang diperankan oleh tokoh-tokoh tertentu. Dalam penelitian ini mengunakan pendekatan Kualitatif dengan teknik pengumpulan data Library research dan field research yaitu data observasi dan wawancara. Dari penelitian ini memiliki tujuan yakni mengetahui jejak nilai Iman Kristen dalam kepemimpinan Tallu Lalikan di Lembang Limbong Sangpolo. Hasil dari penelitian berdasarkan obvervasi dan wawancara, pemimpin dari tiga unsur tersebut, memiliki hati seperti hamba, integritas, spiritual iman kristen dan bertanggung jawab. Kepemimpinan Tallu Lalikan akan membangun relasi yang baik dan akan menghasilkan kehidupan bermasyarakat yang berkualitas.

Kata Kunci: Iman Kristen, kepemimpinan, pemerintahan dan tallu lalikan
Формирование ароматического профиля пивоваренной продукции
Authors: Грибкова Ирина Николаевна , Лазарева Ирина Валерьевна 
Published: June 2023

Введение. В данном обзоре проанализированы современные исследования (с 2015 по 2022 гг.), посвященные вопросу создания ароматического профиля пивоваренной продукции при условии соблюдения всех требований, предъявляемых к готовой продукции в рамках действующих в отрасли стандартов качества.Цель. Целью обзора являлся анализ влияния применяемого растительного сырья, а также микроорганизмов на формирование ароматического профиля пива, в отношении положительных и отрицательных моментов с точки зрения качества готовой пивоваренной продукции. Материалы и методы. Для обзора использованы научные публикации российских и за¬рубежных авторов по вопросам формирования ароматического и вкусового профила пивоваренной продукции за счет органических соединений зернового и растительного сырья. Поиск научных материалов (опубликованных статей) по исследуемой теме на русском и английском языках осуществлялся в базах данных Wed of Science Core Collection, Scopus и eLibrary.ru. В качестве метода исследования использовано обобщение результатов.Результаты. Рассмотрен ограниченный перечень зернового немодифицированного сырья, вклад его органических соединений в ароматический профиль пива. Отмечено положительное влияние разнообразных классов соединений, влияющих на образование летучего профиля пива, с одной стороны, и недостаток низкомолекулярных соединений, обеспечивающих активную бродильную активность микроорганизмов. Рассмотрено влияние специфических органических соединений модифицированного зернового сырья, их вклад в формирование различных ароматических оттенков, что расширяет ассортимент пивоваренной продукции. Рассмотрены нежелательное влияние недостатка низкомолекулярных углеводных и азотистых соединений, а также наличие свободных фенольных форм веществ, способных оказывать негативное влияние на качество пива. Приводится информация о влиянии штаммов дрожжей, их разнообразном метаболизме и вкладе в формирование профиля пивоваренной продукции. Отмечен исследовательский интерес к расширению перечня гибридных штаммов для создания новых органолептических оттенков, которые могут иметь нежелательный характер и привносить в пиво посторонние тона. Выводы. Авторами отмечается, что в рамках действующих требований в рамках ГОСТ 31711-2012, ограничивающих перечень применяемого растительного сырья для производства пива, вопрос формирования различных ароматов все еще остается открытым, несмотря на ощутимые научные достижения в области разнообразия сырьевой базы.