bluuebunny/crossref_metadata_2025_split huggingface dataset:
O “velho” e o “novo” no projeto de desenvolvimento para o semiárido brasileiro
Authors: Silva José Irivaldo Alves Oliveira , Oliveira John Brehmer de Sousa Alves 
Published: June 2023

O Projeto de Integração do São Francisco (PISF) se apropria em seu discurso de fundamentos e estratégias, de conceitos ambientais relacionados à categoria do desenvolvimento sustentável, expressos em seu Programa de Revitalização (PRSF), nos programas socioambientais e ações compensatórias e promete “novos” tempos de prosperidade para o povo nordestino. Isso ocorre em virtude de pelo menos três fatores: o surgimento da sustentabilidade como imperativo ético e conceito normativo na política local, movimento impulsionado por uma mudança e exigência da política global; a necessidade de maior segurança ambiental ao desenvolvimento econômico e social em um contexto de marcante degradação ambiental; e como forma de legitimá-lo entre setores da sociedade civil organizada no semiárido. A presente pesquisa teve como objetivo geral compreender o lugar do desenvolvimento sustentável no PISF e o processo de modernização ecológica observado sobre o mesmo. Como objetivos específicos a análise sobre seus (a) arranjos institucionais e atuação do Estado na implementação de medidas socioambientais; (b) o jogo das “sustentabilidades" nesse empreendimento; e (c) os discursos, práticas e conflitos em seu entorno.
Keywords: Transposition, Environment, Sustainable development

Abstratc
The São Francisco Integration Project (PISF) is framed on fundamentals and strategies of environmental concepts related to the category of sustainable development expressed in its Revitalization Program (PRSF), in the socio-environmental programs and compensatory actions as well as in promises of a “new” era of prosperity for the people of the Northeast. This occurs due to at least three factors: the emergence of sustainability as an ethical imperative and a normative concept in local politics, a movement driven by change and demand from global politics; the need for greater environmental security for economic and social development in a context of significant environmental degradation; and as a means to be legitimized among sectors of organized civil society in the semi-arid. The present research had as a general objective to understand the place of sustainable development in the PISF and the ecological modernization process observed in it. As specific ones there is the analysis of its (a) institutional arrangements and the State’s actions to implement socio-environmental measures; (b) the game of "sustainability"in this enterprise; what is more (c) the discourses, practices and conflicts around it.
Gestão de recursos hídricos e os comitês de bacia hidrográfica em Minas Gerais
Authors: Matos Fernanda Costa de , Saldanha Cristina Camila Teles , Ckagnazaroff Ivan Beck , Carrieri Alexandre de Pádua 
Published: June 2023

Neste estudo buscou-se analisar quais são desafios enfrentados pelos Comitês de Bacias Hidrográficas em Minas Gerais enquanto instâncias deliberativas de governança para a gestão dos recursos hídricos. A partir das percepções de representantes dos 36 comitês mineiros captados por meio de um survey, foram analisados os seguintes tópicos: i) a compreensão por parte dos representantes dos assuntos tratados nos comitês; ii) a composição dos comitês; iii) estruturas administrativas e organizacionais dos mesmos; iv) principais dificuldades e obstáculos; e v) a influência de atuação dos comitês em outras esferas (legislativo estadual e municipal, sociedade civil, setor produtivo e opinião pública). Concluiu-se que ainda há necessidade de aperfeiçoamento quanto à competência técnica dos representantes de governos locais que ainda carecem de capacitação, melhorias nas estruturas com relação às câmaras técnicas que subsidiem a tomada de decisão dos comitês e nos meios de divulgação, além de obstáculos quanto a disponibilidade de recursos financeiros na presença de representantes nas reuniões, principalmente para municípios distantes e da baixa prioridade política. Outros indicativos foram a participação dos comitês em outras esferas, em especial no âmbito político. Isso dificulta a atuação dos comitês como espaços deliberativos efetivos.
Keywords: Watershed Committees, Governance, Deliberation, Participation

Abstratc
This study is intended to analyze the challenges faced by the Water shed Committees in Minas Gerais as deliberative instances of governance for the management of water resources. Based on the perceptions of representatives of the thirty-six committees collected on a survey, the following topics were analyzed: i) the understanding representatives have of the subjects dealt with in the committees; ii) the composition of the committees; iii) their administrative and organizational structures; iv) main difficulties and obstacles; and v) the influence of the committees' in other spheres (state and municipal legislature, civil society, the productive sector and public opinion). It was observed that there is still need to improve technical competence of representatives of local governments who lack training, as well as the structures of technical chambers that support the committees on decision-making and publicity, in addition to obstacles regarding the availability of financial resources, low participation of representatives in the meetings, mainly concerning distant municipalities and lack of political priority. Other indications were the participation of the committees in other spheres, especially in the political one. Therefore, it has been made difficult for the committees to act as effective deliberative spaces.
Rio das Velhas
Authors: Rodney Evandro 
Published: June 2023

A capa deste número contém fotografia do rio das Velhas de autoria do fotográfo Evandro Rodney e criação e design da Assessoria de Comucação (Ascom). O rio é um dos principais afluentes do rio São Francisco e está localizado no município de Barra do Guaicuí, Minas Gerais.
Avaliação da capacidade de escoamento superficial de uma avenida em um município de médio porte da Bahia
Authors: Santos Bethsaide Souza , Aguiar Lucas Gomes 
Published: June 2023

Com a urbanização e consequente aumento da impermeabilização do solo, os centros urbanos estão cada vez mais sujeitos à ocorrência de diversos problemas nas suas respectivas infraestruturas e, alguns desses estão relacionadas à drenagem pluvial. Nesse contexto, torna-se de extrema importância a adoção de medidas preventivas tomadas na fase de pré-desenvolvimento da bacia urbana, tanto estruturais quanto não estruturais. A área de estudo deste trabalho é a avenida Artêmia Pires na cidade de Feira de Santana (BA), que teve e tem o seu processo de expansão urbana não eficazmente planejado pelas competências públicas. Foi analisado o sistema de drenagem pluvial na avenida, que é representado majoritariamente pelo escoamento superficial irregular. Para o geoprocessamento e determinação de áreas de contribuição, foi utilizado o software QGIS e para o cálculo da vazão de contribuição foi aplicado o método racional, e encontrou-se um valor igual a 8,32 m³/s para a avenida. Foram adotados parâmetros de cálculo e assim foi possível determinar a capacidade de deflúvio superficial e determinar áreas onde essa metodologia é mais insatisfatória. Também foi analisado um cenário futuro de maior impermeabilização do solo, onde foi utilizado o coeficiente de escoamento superficial C = 0,70 pra todas as áreas. Foi encontrada uma vazão igual a 32,42 m³/s, e assim firmou-se que a capacidade de drenagem superficial da avenida Artêmia Pires ficará majoritariamente comprometida.
Keywords: Rain drainage. Urban expansion. Urban planning.

Abstract
“Urbanization and the consequent increase in soil sealing makes urban centers increasingly prone to the occurrence of several problems in their respective infrastructures, being some of these are related to rain drainage. In this context, it is extremely important to adopt preventive measures (structural and non-structural) taken in the pre-development phase of an urban basin. The object studied in this work is Artêmia Pires Avenue in the city of Feira de Santana (BA), which hasn’t had its urban expansion process effectively planned by governmental competences. The avenue drainage system, which is mainly represented by irregular runoff, was analyzed. Geoprocessing and determination of contribution areas were done with QGIS software.Rational method was applied to calculate contribution flow, resulting in 8.32 m³/s. Calculation parameters were adopted. Therefore, it was possible to determine the surface defluviation capacity as well as the areas where this methodology is most unsatisfactory. A future scenario of greater soil impermeability was also analyzed in which runoff coefficient C = 0.70 was used for all areas. A flow of 32.42 m³/s was found and thus the surface drainage capacity of Artêmia Pires Avenue was projected. It is likelyto be mostly compromised in this new scenario.”
Rio São Francisco
Authors: Rodney Evandro 
Published: June 2023

A capa deste número contém fotografia do rio São Francisco de autoria do fotográfo Evandro Rodney e criação e design da Assessoria de Comucação (Ascom). A foto refere-se à porção do "Velho Chico" localizada no município de Ibiaí, Minas Gerais.
Avaliação do potencial da cobrança na bacia hidrográfica do rio Chapecó em Santa Catarina
Authors: Beilfuss Bruno Henrique , Kreutz Cristiane , Consolin Filho Nelson 
Published: June 2023

A cobrança pelo Uso dos Recursos Hídricos, como instrumento de gestão, contribui para o uso racional da água, bem público, escasso e tem como impacto sinérgico a arrecadação de recursos para a execução dos planos de bacia. O Estado de Santa Catarina não implementou a Cobrança, e como forma de avaliar seu potencial arrecadação foram analisados os usos de água e demandas de investimento na bacia do Rio Chapecó. Nesta bacia, e considerando valores usuais, o instrumento da Cobrança permite implementar integralmente as ações de planejamento e gestão de recursos hídricos, o que por si só, se configura em um avanço diante das atuais limitações orçamentárias do setor. A cobrança, porém, não é fonte de recursos capaz de individualmente, suprir todos os investimentos indicados no Plano da Bacia como fundamentais para assegurar água em qualidade e quantidade adequadas.
Comunidade zooplanctônica na área de Influência da UHE Jauru, Mato Grosso (MT)
Authors: Landa Giovanni Guimarães 
Published: June 2023

Este estudo foi realizado na área de influência da UHE Jauru, no rio Jauru (MT). Este trabalho teve como objetivo obter uma caracterização limnológica preliminar da área de influência da futura UHE Jauru, através da composição quali-quantitativa do zooplâncton e alguns parâmetros físico-químicos. A coleta de amostras para as análises da comunidade zooplanctônica foi efetuada durante os meses de setembro e outubro de 1994, com rede de plâncton de 35 micrômetros de malha. Foram filtrados 300 litros de água, com auxílio de balde de capacidade de 10 (dez) litros. A análise quantitativa consistiu na contagem de no mínimo 200 indivíduos por amostra, em câmara de Sedgwick-Rafter, sob microscópio binocular. A densidade foi expressa em número de indivíduos por metro cúbico (ind.m-3). A comunidade zooplanctônica durante os meses de setembro e outubro de 1994, estava representada por 35 táxons, dominada por protozoários tecamebas e rotíferos, tanto em riqueza quanto em densidade. O índice médio de diversidade encontrado foi de 1,56 Bits.ind-1. Pode-se considerar também, que baseado nas espécies mais frequentes e abundantes encontradas, o ambiente está classificado numa faixa de baixo teor de carga orgânica, característica essa também demonstrada pelos parâmetros físico-químicos da água.
Keywords: Zooplankton.Lotic environment.Tropical limnology.

Abstract
This study was carried out in the influence area of Jauruhydroelectric power plant, on the JauruRiver (MT). This work aimed to obtain a preliminary limnological characterization of the influence area of the future Jauruhydroelectric power plant, through qualitative and quantitative composition of zooplankton and some physical-chemical parameters. Sample collection for zooplanktonic community analyzes was carried out during the months of September and October 1994, with a plankton net of 35 micrometers of mesh. 300 liters of water were filtered with the aid of a ten-liter bucket. Quantitative analysis consisted of counting at least 200 individuals per sample, in a Sedgwick-Rafter chamber, under a binocular microscope. Density was expressed in number of individuals per cubic meter (ind.m-3). The zooplanktonic community during the months of September and October 1994 was represented by 35 taxa, dominated by protozoans thecamebas and rotifers, both in richness and density. The average diversity index found was 1.56 Bits.ind-1. Based on the most frequent and abundant species found, it can also be considered that the environment is classified in a range of low organic load, a characteristic also demonstrated by the physical-chemical parameters of the water.
Political ideology and belief change in the face of counterevidence
Authors: Kossowska Małgorzata , Czarnek Gabriela , Szwed Paulina 
Published: June 2023

AbstractThis paper investigates the role of political ideology with regard to changes in beliefs on political and non‐political issues. In line with the political asymmetry hypothesis and threat sensitivity accounts in relation to ideology, it was assumed that right‐wing adherents would change their prior beliefs (on political and non‐political issues) to a lesser extent in response to counterevidence than left‐wing adherents. We also expected that the mechanism responsible for this effect would be accounted for by individual differences in threat sensitivity. To test these hypotheses, we conducted two experimental studies (total N = 576) in which participants holding right‐ and left‐wing views were exposed to new information, inconsistent with their prior beliefs, on political and non‐political issues. Contrary to expectations, we found that individuals with right‐ and left‐wing beliefs did not differ in the degree of change to their prior beliefs in response to counterevidence. Nor did we find evidence indicating that threat sensitivity was responsible for the link between ideology and belief change. The paper's findings contribute to the ongoing discussion around ideological (a)symmetry and the controversies concerning threat‐related ideological differences.
Glucan from Dictyophora rubrovolvata boosts immunity by regulating AKT‐STAT1 pathway to induce dendritic cells maturation and T cells differentiation
Authors: Wu Yu , Zhou Wengan , Feng RuTing , Zhang Duoduo , Yu Yongkang , Huang Zuanyuan , Yin Junyi , Zhou Xingtao , Nie Shaoping 
Published: June 2023

AbstractGlucan from fruit body of Dictyophora rubrovolvata (DRP) exerts immunomodulation activity, but the mechanism is still elusive. The immunoregulatory effects of DRP were evaluated using cyclophosphamide (CTX)‐induced immunosuppression in BALB/c mice. Furthermore, bone marrow dendritic cells were used to investigate the activated effect of DRP on immune cells in vitro. This study pointed out that DRP recuperated CTX‐induced immunosuppression of BALB/c mice and activated dendritic cells (DCs) to increase the secretion of cytokines in vitro. RNA‐sequencing showed that DRP upregulated the C‐type lectin receptor (CLR), AKT‐STAT1, and Th17 cell differentiation pathways in DCs. Furthermore, western blot and immunofluorescence confirmed that DRP increased the phosphorylation of AKT and STAT1 and the nuclear translocation of STAT1. Intriguingly, flow cytometry showed that the activation of DCs by DRP was interrupted by Mincle (a CLR) and STAT1 inhibitor. Furthermore, co‐cultured experiments demonstrated that DRP promoted naïve CD4+ T cell differentiation to Th17 cells via the stimulation of DCs. Hence, this study implied that DRP regulated the AKT‐STAT1 signaling pathway via Mincle in DCs to induce CD4+ T cell proliferation and differentiation, thereby ameliorating CTX‐induced immunosuppression.
Expressing passion for luxury enhances perceived authenticity
Authors: Jung SungJin , Chen Charlene , Yap Andy 
Published: June 2023

AbstractConsumers are often viewed unfavorably when using luxury products. They are seen as seeking status and managing impressions, and therefore judged as inauthentic. How can luxury consumers alleviate these negative social consequences? Our pilot studies suggest that although many consumers are passionate about luxury products and brands, they avoid sharing this passion with others because they fear being judged negatively. However, we propose that publicly expressing one's passion for luxury can mitigate the social costs of luxury consumption. Six experiments (including three supplemental experiments) show that expressing passion for luxury causes others to perceive luxury consumers as more authentic, consequently increasing perceptions of their warmth and trustworthiness, and leading others to demonstrate greater interest in knowing more about them. Expressing passion for luxury enhances perceived authenticity by prompting observers to attribute the luxury consumption more to intrinsic motivation (e.g., consuming luxury for inherent enjoyment and pleasure) rather than extrinsic motivation (e.g., status enhancement). The effects of passion expression are attenuated for non‐luxury consumption because non‐luxury consumption is generally unlikely to elicit inferences about extrinsic motives.
Immune checkpoint blockade therapy for BRAF mutant metastatic colorectal cancer: the efficacy, new strategies, and potential biomarkers
Authors: Zhong Jie , Sun Zijian , Li Sheng , Yang Liu , Cao Yuepeng , Bao Jun 
Published: June 2023

AbstractBRAF mutant metastatic colorectal cancer has long been considered a tumor with a poor prognosis and a poor response to chemotherapy. Despite the efficacy of targeted therapy with multi-targeted blockade of the mitogen-activated protein kinase (MAPK) signaling pathway has brought a glimmer of hope to this group of patients, the need to improve treatment efficacy remains unmet, especially for the microsatellite stability/DNA proficient mismatch repair (MSS/pMMR) subtype. BRAF mutant colorectal cancer patients with high microsatellite instability/DNA deficient mismatch repair (MSI-H/dMMR) have high tumor mutation burden and abundant neoantigen, who are deemed as ones that could receive expected efficacy from immunotherapy. Generally, it is believed that MSS/pMMR colorectal cancer is an immunologically “cold” tumor that is insensitive to immunotherapy. However, targeted therapy combined with immune checkpoint blockade therapy seems to bring light to BRAF mutant colorectal cancer patients. In this review, we provide an overview of clinical efficacy and evolving new strategies concerning immune checkpoint blockade therapy for both MSI-H/dMMR and MSS/pMMR BRAF mutant metastatic colorectal cancer and discuss the potential biomarkers in the tumor immune microenvironment for predicting immunotherapeutic response in BRAF mutant colorectal cancer.
Comparison of the different anti-CD16 antibody clones in the activation and expansion of peripheral blood NK cells
Authors: Kim Jinho , Phan Minh‑Trang Thi , Hwang Ilwoong , Park Jeehun , Cho Duck 
Published: June 2023

AbstractNatural killer (NK) cells are promising tool for cancer treatment. Methods have been developed for large-scale NK cell expansion, including feeder cell-based methods or methods involving stimulation with NK cell activating signals, such as anti-CD16 antibodies. Different clones of anti-CD16 antibodies are available; however, a comprehensive comparison of their differential effects on inducing NK cell activation and expansion has not been conducted among these various clones under the same experimental conditions. Herein, we found that the NK cell expansion rate differed depending on the various anti-CD16 antibodies (CB16, 3G8, B73.1, and MEM-154) coated on microbeads when stimulated with genetically engineered feeder cells, K562‑membrane-bound IL‑18, and mbIL‑21 (K562‑mbIL‑18/-21). Only the CB16 clone combination caused enhanced NK cell expansion over K562‑mbIL‑18/-21 stimulation alone with similar NK cell functionality. Treatment with the CB16 clone once on the initial day of NK cell expansion was sufficient to maximize the combination effect. Overall, we developed a more enhanced NK expansion system by merging a feeder to effectively stimulate CD16 with the CB16 clone.
Risk analyses of nocturia on incident poor sleep and vice versa: the Nagahama study
Authors: Negoro Hiromitsu , Setoh Kazuya , Fukunaga Arinobu , Kawaguchi Takahisa , Funada Satoshi , Yoshino Takayuki , Yoshimura Koji , Mathis Bryan J. , Tabara Yasuharu , Matsuda Fumihiko , Ogawa Osamu , Kobayashi Takashi 
Published: June 2023

AbstractCross-sectional relationships between nocturia and sleep problems have been well evaluated but the risk association for each incidence is scarcely reported. This analysis included 8076 participants of the Nagahama study in Japan (median age 57, 31.0% male) and associations between nocturia and self-reported, sleep-related problems (poor sleep) were evaluated cross-sectionally. Causal effects on each new-onset case were analyzed longitudinally after 5 years. Three models were applied: univariable analysis, adjustment for basic variables (i.e., demographic and lifestyle variables) and full adjustment for basic and clinical variables. The overall prevalences of poor sleep and nocturia were 18.6% and 15.5%, while poor sleep was positively associated with nocturia (OR = 1.85, p < 0.001) and vice versa (OR = 1.90, p < 0.001). Among 6579 good sleep participants, 18.5% developed poor sleep. Baseline nocturia was positively associated with this incident poor sleep (OR = 1.49, p < 0.001, full adjustment). Among 6824 non-nocturia participants, the nocturia incidence was 11.3%. Baseline poor sleep was positively associated with this incident nocturia (OR = 1.26, p = 0.026); such associations were significant only in women (OR = 1.44, p = 0.004) and under-50-year-old groups (OR = 2.82, p < 0.001), after full adjustment. Nocturia and poor sleep associate with each other. Baseline nocturia can induce new-onset poor sleep while baseline poor sleep may induce new-onset nocturia only in women.