bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Prophylactic Vitamin D Supplementation on Postoperative Pain and Sedation in Children with Mental Motor Retarded Who Undergoing Dental Treatment Introduction
Authors: BİRİCİK Ebru , ALPAY Nilgün , KARACAER Feride , CİFTCİ Volkan , ILGINEL Murat Türkeün , GORUROGLU OZTURK Ozlem , ÖZCENGİZ Dilek 
Published: March 2023

The frequency of vitamin D deficiency is higher in children with mental motor retardation(MMR). We aimed to investigate the effect of vitamin D supplementation on postoperative pain in children with MMR who underwent dental treatment under general anesthesia.
Materials-Methods: Dental treatment was planned for a total of 62 patients with MMR, aged 7-17 years. Participants were divided into two groups. Children were prescribed vitamin D (600 IU of vitamin D per day) or Saline. Serum vitamin D levels were measured. Participants continued to intake oral vitamin D 600 IU (Group D) or 2ml saline (Group C) throughout 12 weeks. All participants were observed postoperative 1st hour, and Non-communicating Children's Pain Checklist–Postoperative Version (NCCPC-PV), Ramsay sedation scores, length of stay in post-anesthesia care unit, and analgesic requirements were recorded.
Results: The study was completed with fifty children (35 in Group D, 15 in Group C). Serum vitamin D levels were higher in Group D than Group C at 12 weeks(p=0.007). Vitamin D deficiency was found at 13 patients (37.1%) and 6 (40%), and vitamin D sufficiency was found 18 (51.4%) and 7 (46.7%) in Groups D and C, respectively at first admission. There was statistically significant difference between groups in NCCPC-PV score at 15th, 30th and 60th minutes in PACU(p
ENERGY COLLOCATION METHOD FOR THE TRUSS FUNDAMENTAL FREQUENCY ESTIMATION
Authors: Кирсанов М.Н. 
Published: March 2023

Предлагается вариант метода Рэлея для расчета первой собственной частоты колебаний фермы. Используется приближенная оценка потенциальной и кинетической энергии системы. Если потенциальная энергия рассчитывается по сумме потенциальных энергий всех масс, то суммарная кинетическая энергия масс заменяется приближенным выражением, рассчитанным по максимальной кинетической энергии одного из узлов. Для примера приводится вывод формулы для первой собственной частоты плоской статически определимой балочной фермы с треугольной решеткой с произвольным числом панелей. Предполагается, что колебания масс, расположенных в узлах фермы, происходят только по вертикали. Жесткость фермы рассчитывается по формуле Максвелла – Мора. Сравниваются результаты, полученные по предлагаемому методу, методу Рэлея и методу Донкерлея. Все преобразования производятся в аналитическом виде с использованием системы компьютерной математики Maple. Результаты обобщаются на произвольное число панелей методом индукции. Показано хорошее совпадение предложенного метода с методом Рэлея и первой частотой, найденной численно с учетом всех степеней свободы фермы.
A variant of the Rayleigh method for calculating the first natural frequency of the truss oscillations is proposed. An approximate estimate of the potential and kinetic energy of the system is used. If the potential energy is calculated from the sum of the potential energies of all masses, then the total kinetic energy of all masses is replaced by an approximate expression calculated from the maximum kinetic energy of one of the nodes. A recommendation is given on the choice of this node. For example, the derivation of the formula for the first natural frequency of a plane statically determined truss with a triangular lattice is given. It is assumed that the oscillations of the masses located in the truss nodes occur only along the vertical. Truss stiffness is calculated using the Maxwell – Mohr formula. The results obtained by the proposed method, the Rayleigh method and the Dunkerley method are compared. All transformations are performed in an analytical form using the Maple computer mathematics system. The results are generalized to an arbitrary number of panels by induction. A good agreement between the proposed method and the Rayleigh method and the first frequency found numerically, taking into account all degrees of freedom of the truss, is shown.
EXPERIMENTAL STUDY OF THE AERODYNAMIC CHARACTERISTICS OF THE LARGE-SPAN BUILDING
Authors: Сатанов А.А. , Симонов А.В. , Хазов П.А. 
Published: March 2023

Приводятся и анализируются результаты исследования распределения аэродинамических коэффициентов по поверхности большепролетного криволинейного покрытия проектируемого здания. Геометрическая форма покрытия здания не совпадает с предложенными в нормативных документах, вследствие чего для определения аэродинамических характеристик был выбран метод проведения эксперимента с макетом здания в аэродинамической трубе. Были получены изополя распределения аэродинамических коэффициентов по покрытию здания. Результаты эксперимента показывают, что на покрытие действует преимущественно отрицательное давление, значения коэффициентов распределяются крайне неравномерно в связи с наличием сложных изгибов его поверхности, а также имеет место взаимное влияние разновысотных частей здания друг на друга.
The results of the study of the distribution of aerodynamic coefficients over the surface of a long-span curvilinear roofing of the designed building are given and analyzed. The geometric shape of the building roofing does not match with the ones presented in the regulatory documents, so the method of conducting an experiment with a building model in a wind tunnel was chosen to determine the aerodynamic characteristics. The isofields of the distribution of aerodynamic coefficients over the roofing of the building were obtained. The results of the experiment show that the roofing is mainly affected by negative pressure, the values of the coefficients are distributed extremely unevenly due to the presence of complex bends of its surface, and there is a mutual influence of parts of the building of different heights on each other.
PROBABILISTIC RELIABILITY ASSESSMENT OF NORMAL SECTION OF A BENDED REINFORCED CONCRETE BEAM WITH STEEL FIBER
Authors: Сафронов В.С. , Киселев Д.А. 
Published: March 2023

Описывается и апробируется методика нелинейного деформационного расчета прочности нормального сечения изгибаемой железобетонной балки со стальной фиброй с использованием кусочно-линейной диаграммы деформирования сталефибробетона и стержневой арматуры. Исследуется влияние на несущую способность процентного содержания фибры в балке прямоугольного поперечного сечения. Предложенный алгоритм применяется для вероятностной оценки надежности усиленной стальными волокнами железобетонной балки с учетом разброса прочностных характеристик сталефибробетона и стержневой арматуры. Приводятся графики изменения логарифмического показателя надежности нормального сечения в зависимости от процентного содержания фибры и коэффициента вариации прочности сталефибробетона.
The methodology of non-linear deformation calculation of the normal section of the bending reinforced concrete beam with steel fiber using a piece of line-linearity of steelfibrite reinforcement and core reinforcement is described and tested. The impact on the bearing capacity of the percentage of the fiber in the beam of a rectangular cross section The proposed algorithm is used for probabilistic assessment of reliability reinforced by steel fibers of the reinforced concrete beam, taking into account the spread of the strength characteristics of steelfibrite concrete and rod reinforcement. Graphs of changes in the logarithmic indicator of the reliability of the normal section depending on the percentage of the fiber and the coefficient of variation of the strength of steelfibrite concrete.
Representation of Nigerian Internet Scamsters in selected Nigerian and International News Reports
Authors: Olawe Opeyemi Emmanuel 
Published: March 2023

Linguistic studies on Nigerian internet scamsters have dwelt on the aspects of language use. These studies focused on the linguistic features, slangy expressions, discourse and persuasive strategies used by scamsters in scam messages. However, the aspect of media representation of the social actors of Nigerian internet fraud has not been given adequate attention. This study, therefore, explores the representation of social actors of Nigerian internet fraud in Nigerian and international news reports. Headlines and news contents are purposively sampled from forty-five news articles published between 2019 and 2021, from two Nigerian newspapers and two international news media. Guided by Halliday’s Systemic Functional Grammar (SFG) and Van Leeuwen’s early work on social actor representation (1996), ten forms of representations were identified. Nigerian Internet Scamsters were represented as educated, role models, imposters, parentally supported, abductors, wrong ambassadors/negative nationals, friends to the security agents, desperate/money ritualists, guilty and convicted, exploiters and victimizers. The negative connotation of these labels indicates that the media are not neutral in their representation of scammers. This study shows that the representation of the social actions and actors in internet fraud are linguistically and discursively framed to fit their ideology.
Enchondroma Presenting with an Acutely Painful Hand
Authors: Jose Tom , Mathew Thomas , Iqbal Awais 
Published: March 2023

Enchondromas are intramedullary cartilage neoplasms with benign imaging features that constitute approx. 90% of benign tumours in the hands.
We present a 25-year-old previously fit and well female patient with Enchondroma of the metacarpal bone with characteristic imaging and pathologic fracture to increase its awareness for early diagnosis and treatment.
Éclairages sur la protection de l’eau en période de conflit armé : pour un renouvellement de l’approche juridique
Authors: Tagus Charlotte 
Published: March 2023

À plus forte raison au regard du visage que prennent les conflits armés contemporains, les enjeux que pose la protection de l’eau en période de conflit armé (Peca) mettent en évidence le caractère lacunaire du droit international humanitaire (DIH) en la matière. Cet article en étudie les facteurs déterminants et, partant, la nécessité de renouveler l’approche juridique afférente. À la croisée du droit international des droits de l’homme et du droit international de l’eau, nous envisagerons la perspective d’une approche plus spécifique et intégrée du DIH, à la lumière du droit de la paix pertinent au renforcement de la protection de la ressource.
Entre tensions électriques et géopolitiques : les enjeux énergétiques et de ressources en Asie centrale au prisme du minage de cryptomonnaies
Authors: Estecahandy Hugo 
Published: March 2023

Le minage de cryptomonnaies, activité numérique énergivore lorsqu’elle est déployée à l’échelle industrielle, qui consiste à utiliser de la puissance de calcul informatique pour sécuriser des réseaux financiers alternatifs, a été grandement développé en Asie centrale et notamment au Kazakhstan. La hausse de la consommation électrique engendrée par l’industrie serait, d’après les autorités locales, à l’origine de la crise énergétique traversée par la région. En étudiant les dynamiques géopolitiques qui ont entraîné le développement du minage au sein de cet espace, cet article met en lumière des enjeux d’énergie et de ressources intrinsèques à la région, menaçant la stabilité de ces pays interdépendants. Cette analyse met en avant que, si le développement du minage a effectivement pu contribuer à augmenter la consommation énergétique régionale, il a été facilité par une certaine corruption également responsable de la désuétude du réseau électrique partagé entre le Kazakhstan, l’Ouzbékistan et le Kirghizistan.
Changement climatique et crise énergétique : nouvelle donne pour le nucléaire civil mondial
Authors: Lewandowski Cédric 
Published: March 2023

L’article propose un état des lieux de l’énergie nucléaire civile dans le monde et des enjeux géopolitiques associés. Deuxième source d’électricité bas carbone dans le monde, la première au sein de l’UE, elle constitue un atout majeur pour lutter contre le changement climatique. Elle contribue également, dans la durée, à la sécurité d’approvisionnement en électricité et au développement économique des pays qui l’utilisent. C’est à l’aune de ces différents critères que s’apprécie le « retour en grâce » du nucléaire observé dans plusieurs pays européens depuis 2020. La « diplomatie nucléaire » est dès lors plus active que jamais : alors que le barycentre du nouveau nucléaire est aujourd’hui en Russie et en Chine, les États-Unis sont très engagés pour retrouver leur leadership en soutenant massivement leur recherche et leur industrie nationale, notamment dans le domaine des petits réacteurs modulaires, et en développant leurs partenariats internationaux. Dans ce contexte, la réussite de la reprise de la grande aventure du nucléaire civil en France passe par un grand projet national autorisant une mobilisation humaine, industrielle et financière qui lui permettra de recouvrer sa vocation de puissance nucléaire.
De l’annexion de la Crimée en 2014 à l’invasion de l’Ukraine en 2022 : extension et application des normes européennes au Nord Stream 2
Authors: Ramdani Sami 
Published: March 2023

En réaction au développement du Nord Stream 2, la Commission européenne a proposé d’amender la directive gaz en 2017. Dans un premier temps, nous resituons le processus ayant vu émerger cet amendement jusqu’à son adoption en 2019. Puis, nous analysons les multiples tentatives de Nord Stream 2 AG pour contourner l’application des normes européennes. Certaines de ces procédures ont été suspendues par l’invasion de l’Ukraine, d’autres sont toujours en cours. Enfin, nous concluons en constatant l’impact qu’a eu cet amendement. Cette évolution législative visant des objectifs stratégiques marque une nouvelle étape de l’usage géopolitique du droit par la Commission européenne.
Epidermal Growth Factor Receptor in Hepatic Endothelial Cells Suppresses MCP-1–Dependent Monocyte Recruitment in Diabetes
Authors: Zhang Xinyi , Ohayon-Steckel Lee , Coppin Emilie , Johny Ebin , Dasari Ankush , Florentin Jonathan , Vasamsetti Sathish , Dutta Partha 
Published: March 2023

Abstract
Insulin resistance is a compromised response to insulin in target tissues such as liver. Emerging evidence shows that vascular endothelial cells (ECs) are critical in mediating glucose metabolism. However, how liver ECs can regulate inflammation in the setting of insulin resistance is still unknown. Using genome-wide transcriptome analysis of ECs isolated from diabetic mice, we found enrichment of the genes involved in epidermal growth factor receptor (Egfr) signaling. In line with this, hepatic sinusoidal ECs in diabetic mice had elevated levels of Egfr expression. Interestingly, we found an increased number of hepatic myeloid cells, especially macrophages, and systemic glucose intolerance in Cdh5Cre/+Egfrfl/fl mice lacking Egfr in ECs compared with littermate control mice with type II diabetes. Egfr deficiency upregulated the expression of MCP-1 in hepatic sinusoidal ECs. This resulted in augmented monocyte recruitment and macrophage differentiation in Cdh5Cre/+Egfrfl/fl mice compared with littermate control mice as determined by a mouse model of parabiosis. Finally, MCP-1 neutralization and hepatic macrophage depletion in Cdh5Cre/+Egfrfl/fl mice resulted in a reduced number of hepatic macrophages and ameliorated glucose intolerance compared with the control groups. Collectively, these results demonstrate a protective endothelial Egfr signaling in reducing monocyte-mediated hepatic inflammation and glucose intolerance in type II diabetic mice.
Investigating Thymic Epithelial Cell Diversity Using Systems Biology
Authors: Chiu Honyin , Linsley Peter S , Ziegler Steven F 
Published: March 2023

Abstract
The thymus is an intricate organ consisting of a diverse population of thymic epithelial cells (TECs). Cortical and medullary TECs and their subpopulations have distinct roles in coordinating the development and selection of functionally competent and self-tolerant T cells. Recent advances made in technologies such as single-cell RNA sequencing have made it possible to investigate and resolve the heterogeneity in TECs. These findings have provided further understanding of the molecular mechanisms regulating TEC function and expression of tissue-restricted Ags. In this brief review, we focus on the newly characterized subsets of TECs and their diversity in relation to their functions in supporting T cell development. We also discuss recent discoveries in expression of self-antigens in the context of TEC development as well as the cellular and molecular changes occurring during embryonic development to thymic involution.
Three-Dimensional Human Bone Marrow Organoids for the Study and Application of Normal and Abnormal Hematoimmunopoiesis
Authors: de Janon Alejandro , Mantalaris Athanasios , Panoskaltsis Nicki 
Published: March 2023

Abstract
Hematoimmunopoiesis takes place in the adult human bone marrow (BM), which is composed of heterogeneous niches with complex architecture that enables tight regulation of homeostatic and stress responses. There is a paucity of representative culture systems that recapitulate the heterogeneous three-dimensional (3D) human BM microenvironment and that can endogenously produce soluble factors and extracellular matrix that deliver culture fidelity for the study of both normal and abnormal hematopoiesis. Native BM lymphoid populations are also poorly represented in current in vitro and in vivo models, creating challenges for the study and treatment of BM immunopathology. BM organoid models leverage normal 3D organ structure to recreate functional niche microenvironments. Our focus herein is to review the current state of the art in the use of 3D BM organoids, focusing on their capacities to recreate critical quality attributes of the in vivo BM microenvironment for the study of human normal and abnormal hematopoiesis.
The Qualitative Study of Gender Bias in Medicine: The Cyclic Effect
Authors: Sharma Neeraj , Sharma Ananya , Sharma Chetna 
Published: March 2023

ABSTRACT

Background:
The development of a medical workforce that enables universal access to safe, just, and equitable healthcare is hampered by gender-related inequality and disparity.

Aim:
Our goal in this study is to comprehend how gender prejudice has a cyclical impact that spreads from the fields of education and research to clinical practice.

Materials and Methods:
We conducted a qualitative study in which we collected information from faculty members and MBBS students through individual interviews. The transcripts of the interviews were analyzed thematically.

Results and Discussion:
The participants reported a culture that reinforces gendered standards in both education and clinical practice. There is a gender bias in mentoring, learning support, and reading materials offered to students, which often spills into clinical practice and impacts how healthcare is delivered.

Conclusion:
According to our research, there is a cyclic effect of women’s exclusion in medical education, research, and clinical practice that is caused by gender bias. These results highlight the need for gender-just systems of education, research, and clinical care to successfully address gender prejudice.
AS PERCEPÇÕES DE GÊNERO, O ACOLHIMENTO INSTITUCIONAL DE CRIANÇAS E O SERVIÇO SOCIAL
Authors: Petroski Machado Gabriele , Rolim de Moura Reidy 
Published: March 2023

A desigualdade de gênero é um elemento que deve ser considerada ao deparar-se com a realidade das crianças acolhidas institucionalmente no que tange o contexto familiar dessas crianças e os papéis sociais do homem e da mulher na família. Trata-se de um estudo qualitativo de natureza descritiva e exploratória, construído a partir da pesquisa bibliográfica, revisão documental e das vivências de uma estagiária de serviço social na Vara da Infância e Juventude de Ponta Grossa e pesquisadora da temática de gênero. Este artigo é fruto da pesquisa realizada para o Trabalho de Conclusão de Curso de umas das autoras e tem como principal objetivo apresentar de que forma se expressam as questões de gênero no processo de acolhimento institucional de crianças no município de Ponta Grossa/PR. Os principais resultados obtidos demonstraram que a condição de gênero está relacionado com os motivadores geradores do acolhimento institucional da crianças, ainda que não explicitamente, porém os dados demonstram que a desigualdade de gênero está presente neste processo. A sobrecarga da mulher nos cuidados domésticos e dos filhos é um fator que chama atenção para este processo, além do histórico familiar que reflete a repetição da violência nas famílias, mulheres que também viveram o abandono, negligências e violências em suas infâncias, acabam reproduzindo com seus filhos e diante desta realidade se reconhece a importância da atuação do serviço social no combate à violação dos direitos das crianças e também das mulheres e promover ações e serviços que atendam as demandas das garantias dos direitos.
Penegakan Hukum Hak Cipta Terhadap Download Film Pada Situs Ilegal
Authors: Hahury Arixellis Juan Efraim , Narwadan Theresia Nolda Agnes , Labetubun Muchtar Anshary Hamid 
Published: March 2023

Introduction: Copyright is the exclusive right of the creator that arises automatically based on declarative principles after a work is realized in a tangible form, without reducing restrictions in accordance with the provisions of laws and regulations. Copyright has been protected by Law Number 28 of 2014. But in reality, there are still many copyright violations such as downloading movies on sites on illegal sites.Purposes of the Research: This study aims to determine Copyright Law Enforcement Against Downloading Films on Illegal Sites. Methods of the Research: The type of research used in this thesis is the type of empirical research. The data collection method used is the method of observation, interviews and literature then the data obtained were analyzed descriptively qualitatively so as to reveal the expected results and conclusions on the problem.Results of the Research: The results of the study show that the enforcement of copyright law on downloading films on illegal sites has not been carried out in accordance with applicable law. This is based on the fact that copyright law enforcement is influenced by several factors, namely legal factors, law enforcement, infrastructure, society and culture. Legal factors, in this case the Law, have contained regulations related to copyright, but law enforcement factors have not been effective in carrying out their duties. In addition, the infrastructure factor in this case is related to the lack of support for communication facilities which is an obstacle related to reporting copyright infringement. Then the community factor and cultural factor, in this case the community still commits violations related to film copyright.