bluuebunny/crossref_metadata_2025_split huggingface dataset:
Partial Excision of a Tibial Sesamoid Fracture Nonunion in a Patient with Congenital Absence of Fibular Sesamoid: A Case Study
Authors: Vesely Bryanna , Sikora Rebecca R. , Dial Dekarlos 
Published: May 2023

Background: Hallucal sesamoid injuries occur in approximately 5% to 10% of foot and ankle injuries. Most cases can be treated conservatively. However, when nonoperative management fails, surgical intervention is warranted.
Methods: The present case involved a 17-year-old female high school senior who presented to the clinic with right hallux pain. Radiographs were obtained and revealed congenital absence of the fibular sesamoid and evidence of a minimally displaced avulsion fracture involving the proximal medial tibial sesamoid. Treatment was complicated by the congenital absence of the fibular sesamoid and by a high activity level.
Results: After conservative treatment failure, the patient underwent partial excision of her tibial sesamoid. She was followed for 1.5 years after initial presentation to our clinic. The patient was able to return to daily activities; however, she was not able to return to softball competitively due to pain.
Conclusions: We hypothesize she was unable to return to softball because the absence of a sesamoid can decrease push-off strength. We recommend that providers treating athletes educate their patients on the possible loss of strength and take this into account when creating a treatment plan.
Morphometric Features of Cells of Cervical Intraepithelial Neoplasia Using Computer Aided Image Analysis
Authors: Olaniyi Olaofe Olaejirinde , Morakinyo Akinyemi Hezekiah , Oluwole Komolafe Akinwumi 
Published: May 2023

Aim: Our goal is to evaluate and compare the different cell morphometric parameters in the various categories of cervical intraepithelial neoplasia (CIN).
Study Design: We conducted a cross-sectional study of all cervical intraepithelial neoplasia identified in some areas of biopsies of cervical carcinomas.
Place and Duration of Study: The study was in the department of histopathology of LAUTECH Teaching Hospital, Osogbo from January 2006 to December 2015.
Materials and Methods: The histologic slides produced were scanned using CS2 APERIO digital slide scanner with standard settings. The scanned slides were then viewed using Qu Path-0.3.2 software. All areas of cervical intraepithelial neoplasia were selected. The perimeter, area, maximum caliper, circularity, eccentricity, and the various measures of hematoxylin optic densities (OD) of the nucleus of the cells were measured. The cytoplasmic morphometric measurements and the nuclear-cell ratio were then estimated.
Results: Two cases of CIN 1, one case of CIN 2 and one case of CIN 3 were seen in the background of the eighty-seven cases of cervical carcinomas seen during the study period. A total of 5,935 cells were in the annotated regions with cervical intraepithelial neoplasia. The cells in CIN 1 area are 3,828, CIN 2 area has 1183 cells and CIN 3 areas has 924 cells. Cells of CIN 3 had higher average nuclei hematoxylin optic density (OD), nuclei hematoxylin OD standard deviation and maximum hematoxylin OD than cells of CIN 2 and CIN 1. Cells of CIN 1 have higher average cell area, cell perimeter, cell circularity and mean cytoplasm eosin OD compared to cells of CIN 2 and 3.
Conclusion: Computer-aided image analysis using Qu Path software can be very instrumental in differentiating the various categories of cervical intraepithelial neoplasia especially in fragmented biopsies.
The Correlation between QRS Dispersion and Coronary Artery Disease Severity in Patients with Non ST Elevation Myocardial Infraction
Authors: Boudhar Zainab , Nehame Sana , El-Jamili Mohammed , El-Karimi Saloua , El-Hattaoui Mustapha 
Published: May 2023

Non ST elevation myocardial infarction (NSTEMI) has been the subject of numerous studies. Risk stratification is a fundamental element for the management of NSTEMI; therefore, several scores have been established in this direction, particularly prognostic markers derived from the ECG.
Aims: The aim of our study is to correlate the dispersion of the QRS with the severity of coronary lesions assessed by the GENSINI score in patients admitted for NSTEMI at the University Hospital of Marrakech.
Methods: A retrospective study was conducted in the cardiology department of Mohammed VI university hospital of Marrakech from January 01, 2022 to March 31, 2022. Data was derived from the hospitalization register, including 30 patients (16 women and 14 men). Age ranged from 56 to 74 years with an average of 64.6 ± 9.3. Data was analyzed by SPSS, the level of significance set at p <0.05.
Results: We found, in our study, a highly significant positive correlation between QRS dispersion (considered important if >20 ms) and admission heart rate (p=0.003) as well as the level of ultrasensitive troponins (p=0.003). There is also a very significant correlation between QRS dispersion and corrected QT interval (p=0.005), Moreover, we concluded that in patients admitted for NSTEMI, the greater the dispersion of the QRS, the higher the score of GENSINI (p<0.0001).
Conclusion: The dispersion of the QRS is a simple marker on the ECG that can have a predictive value in different clinical contexts, particularly in acute ischemic heart disease. Further studies are needed, however, to validate its usefulness in routine practice.
Effect of Moisture Content and Particle Size on Characteristics of Fuel Pellets Using Flat Die Type Pelleting Machine
Authors: Jagtap Abolee , Kalbande Surendra 
Published: May 2023

Fuel pellets are a popular form of biomass energy due to their high energy density, ease of handling, and reduced emissions. The quality of fuel pellets is influenced by various factors, including the moisture content and particle size of the raw materials (Soybean straw and cotton stalk) used during the pelletization process. In this study, the effect of moisture content and particle size on the characteristics of fuel pellets produced using a flat die type pelleting machine was investigated. Different moisture content levels (ranging from 20 to 30%) and particle sizes (ranging from 4 to 8 mm) were used to pelletize a biomass feedstock. The pellet characteristics, including pellet durability, bulk density and water resistance and energy consumption were evaluated. The results showed that both moisture content and particle size significantly influenced the characteristics of the fuel pellets as well as energy consumption. Based on the findings, an optimal moisture content of 25% and particle size of 6 mm were determined for producing fuel pellets with desirable characteristics and low energy consumption was required using the flat die type pelleting machine. These results can provide valuable insights for biomass pellet producers and researchers in optimizing the pelletization process to achieve high-quality fuel pellets with improved properties.
Convergence of Baskakov Durrmeyer Operators in the Reverse Order of q-Analogue
Authors: Garg Sangeeta 
Published: May 2023

This research paper is an introduction to a new type of analogue named as -analogue for well-known Baskakov Durrmeyer operators. This new type of analogue is considered as reverse order of -analogue. In this paper, we establish the direct approximation theorem, a weighted approximation theorem followed by the estimations of the rate of convergence of these new type of operators for functions of polynomial growth on the interval.
Role of Suprachoroidal Anti-VEGF Injections in Recalcitrant Serous Pigment Epithelium Detachment
Authors: Datta Ditsha , Khan Perwez , Khan Lubna , Singh Ankita 
Published: May 2023

Purpose: Retinal pigment epithelial detachments (PEDs) are characterized by a separation between the RPE and the innermost aspect of Bruch's membrane. Many chorioretinal diseases can lead to pigment epithelial detachment of which the most common is age-related macular degeneration; but a significant number of PEDs are idiopathic in etiology. PEDs can be classified as drusenoid, serous, vascularized, or fibrovascular type.
Currently, serous PED has not shown much response to treatment, so no specific treatment guidelines are established. Whereas vascularized PEDs, have several treatment options such as intravitreal anti-Vascular endothelial growth factor (VEGF) therapy, laser photocoagulation, photodynamic therapy (PDT) and intravitreal steroids. Hence, the need of the hour is to formulate a treatment strategy for serous PED.
Methods: We report an original study of thirty patients who were diagnosed with serous pigment epithelial detachment on Spectral-domain optical coherence tomography and fundus fluorescence angiography. All the patients presented to our outpatient department with the chief complaint of diminution of vision, central/paracentralscotoma and metamorphopsia. All of them underwent treatment with suprachoroidal anti-VEGF (bevacizumab).The patients were followed 8 weeks.
Results: BCVA and Amsler grid assessment was recorded on the 3rd day,1st week, 2nd week, 4th week, 6th week, and 8th week. Post-injection SD-OCT macular scan was performed on the 6thweek. Functional improvement (BCVA) was reported by all patients. All the patients had reduced size and height of PED in SD-OCT.
Conclusion: Thus, our result indicates that suprachoroidalbevacizumab is an efficacious treatment for serous PED. It can be hypothesized that as degenerative changes in bruch membrane due to metabolite deposit plays a key role in development of PED; injecting the anti VEGF drug in the suprachoroida space adjacent to the choroid has a superior effect.
A imagem e o processo gerador subjetivo da realidade objetiva: elementos psicológicos e pedagógicos da formação humana à luz da Teoria Histórico-Cultural
Authors: Vieira Saulo , Aguiar Wanda Maria Junqueira de , Ferreira Isabel Cristina Fernandes , Lima Ana Ignez Belém 
Published: May 2023

Esse artigo consiste em um ensaio acerca do processo histórico de construção teórica que envolve o conceito de subjetividade desde os primeiros trabalhos de Vigotski até a extensão de seu legado por meio de Gonzalez-Rey. Aponta a categoria Dimensão Subjetiva da Realidade como elemento analítico central da unidade teórico-metodológica existente entre a Psicologia Histórico-Cultural e a Pedagogia Histórico-Crítica, mais especificamente como condição para reflexão sobre/para uma educação emancipadora para a classe trabalhadora.
A situação social do desenvolvimento infantil
Authors: Bozhovich Lydia , Marília Daefiol Herrero Gomes Tradutora 
Published: May 2023

Neste texto, Bozhovich discute dois conceitos propostos por Vigotski: o conceito psicológico de idade e a situação social do desenvolvimento. Ambos são apresentados como mecanismos que constituem a força motriz do desenvolvimento juntamente com as necessidades básicas das crianças. A segunda parte do capítulo aborda a concepção de Bozhovich a respeito do conceito de perejivanie.
Esta tradução foi realizada com base na seguinte publicação do texto “The social situation of child development” de Lídia Bozhovich publicado no Journal of Russian & East European Psychology. A versão deste mesmo trabalho em espanhol foi utilizada para fins de comparação e para sanar algumas questões de tradução.
Clinical experience in the use of 3D printing as a rapid replacement of traditional radiation therapy immobilization materials
Authors: Ehler Eric D. 
Published: May 2023

AbstractPurposePatient positioning and immobilization devices are commonly employed in radiation therapy. Unfortunately, cases can arise where the devices need to be reconstructed or improved. This work describes clinical processes to use a planning CT, to design and 3D print immobilization devices for reproducible patient positioning within a clinically feasible time frame when traditional methods can no longer be used or are insufficient.Materials/MethodsThree clinical cases required rapid 3D printing of an immobilization device mid‐treatment due to the following: (1) a lost headrest cushion, (2) needed improvement in lumbar spine positioning, and (3) a partially deflated vacuum immobilization mattress.ResultsIn the three cases, the 3D printed immobilization devices were clinically implemented successfully; two of the devices were fully designed and printed in 1 day. The 3D printed immobilization devices achieved a positioning accuracy sufficient to avoid the necessity to repeat the simulation and planning process.ConclusionIf traditional immobilization devices fail or are misplaced, it is feasible to have a 3D printed replacement within the time span of 1 day. The design and fabrication methods, as well as the experiences gained, are described in detail to assist clinicians to implement 3D printing for similar situations.
How Does Exercise, With and Without Diet, Improve Pain and Function in Knee Osteoarthritis? A Secondary Analysis of a Randomized Controlled Trial Exploring Potential Mediators of Effects
Authors: Lawford Belinda J. , Hinman Rana S. , McManus Fiona , Lamb Karen E. , Egerton Thorlene , Keating Catherine , Brown Courtney , Oliver Kathryn , Bennell Kim L. 
Published: May 2023

ObjectiveTo explore the mediators of effects of two 6‐month telehealth‐delivered exercise programs, including exercise with and without weight‐loss diet, on pain and function improvements in knee osteoarthritis (OA).MethodsSecondary analysis of 345 participants from a 3‐arm randomized controlled trial of exercise (Exercise program) and exercise plus diet (Diet + Exercise program) versus information (Control program) was conducted. Outcomes were changes in pain (11‐point numeric rating scale) and function (Western Ontario and McMaster Universities Osteoarthritis Index [score range 0–68]) at 12 months. Potential mediators were change at 6 months in attitudes toward self‐management, fear of movement, arthritis self‐efficacy, weight, physical activity, and willingness for knee surgery. For the Diet + Exercise program versus the Exercise program, only change in weight was evaluated.ResultsPossible mediators of the Exercise program versus the Control program included reduced fear of movement (accounting for –1.11 units [95% confidence interval (95% CI) –2.15, –0.07] improvement in function) and increased arthritis self‐efficacy (–0.40 units [95% CI –0.75, –0.06] reduction in pain, –1.66 units [95% CI –3.04, –0.28] improvement in function). The Diet + Exercise program versus the Control program mediators included reduced fear of movement (–1.13 units [95% CI –2.17, –0.08] improvement in function), increased arthritis self‐efficacy (–0.77 units [95% CI –1.26, –0.28] reduction in pain, –5.15 units [95% CI –7.34, –2.96] improvement in function), and weight loss (–1.20 units [95% CI –1.73, –0.68] reduction in pain, –5.79 units [95% CI –7.96, –3.63] improvement in function). Weight loss mediated the Diet + Exercise program versus the Exercise program (–0.89 units [95% CI –1.31, –0.47] reduction in pain, –4.02 units [95% CI –5.77, –2.26] improvement in function).ConclusionIncreased arthritis self‐efficacy, reduced fear of movement, and weight loss may partially mediate telehealth‐delivered exercise program effects, with and without diet, on pain and/or function in knee OA. Weight loss may partially mediate the effect of diet and exercise compared to exercise alone.
Engaging Multistakeholder Perspectives to Identify Patient‐Centered Research Priorities Regarding Vaccine Uptake Among Adults With Autoimmune Conditions
Authors: Venkatachalam Shilpa , Gavigan Kelly , Banerjee Shubhasree , Gordon Jennifer , Emrich Lisa , Sullivan Hope , Blazer Ashira , Banbury Brittany , Weaver Kimberly N. , Stradford Laura , Dronadula Vandana , Degrassi Angela , Merkel Peter A. , Shaw Dianne G. , Larsen Kalen , Curtis Jeffrey R. , McBurney Robert N. , Kappelman Michael D. , George Michael D. , Nowell W. Benjamin 
Published: May 2023

ObjectiveThe study objective was to prioritize topics for future patient‐centered research to increase uptake of common vaccines, such as for pneumococcal pneumonia, influenza, herpes zoster, human papillomavirus, and severe acute respiratory syndrome coronavirus 2, among adults living with autoimmune conditions.MethodsA steering committee (SC) was formed that included clinicians, patients, patient advocates, and researchers associated with rheumatic diseases (psoriatic arthritis, rheumatoid arthritis, vasculitis), inflammatory bowel disease, and multiple sclerosis. Through a scoping review and discussions, SC members identified research topics regarding vaccine uptake and/or hesitancy for prioritization. A larger multistakeholder alliance that included patients and patient advocates, clinicians, researchers, policy makers, regulators, and vaccine manufacturers conducted a modified Delphi exercise online with three rating rounds and one ranking round. Frequency analysis and comparisons across stakeholder groups were conducted. A weighted ranking score was generated for each item in the ranking round for final prioritization.ResultsThrough the Delphi process, 33 research topics were identified, of which 13 topics were rated as critical by more than 70% of all stakeholders (n = 31). The two highest ranked critical topics per the full stakeholder group were “How well a vaccine works for adults with autoimmune conditions” and “How beliefs about vaccine safety affect vaccine uptake.”ConclusionA multistakeholder group identified key topics as critically important priorities for future research to decrease vaccine hesitancy and improve uptake of vaccines for adults with autoimmune conditions.
Ionic Thermoelectric Properties of Reconstructed Lamellar Vanadium Pentoxide Membranes
Authors: Gogoi Raktim , Madeshwaran Harshan , Ghosh Arnab , Green Yoav , Raidongia Kalyan 
Published: May 2023

AbstractIn recent years, the application of ionic thermoelectric (TE) materials to convert low‐grade waste heat into electricity has become a subject of intense scientific research. However, most of the efforts are focused on organic polyelectrolytes or ionic‐liquids embedded in polymeric gels. Here, for the first time, it is demonstrated that nanofluidic membranes of reconstructed layered materials like vanadium pentoxide (V2O5) exhibit excellent ionic‐TE characteristics. The high Seebeck coefficient (S = 14.5 ± 0.5 mV K‐1) of the V2O5 membrane (VO‐M) is attributed to temperature gradient‐induced unidirectional transport of protons through the percolated network of 2D nanofluidic channels. The TE characteristics of VO‐M show nearly 80% improvement (S = 26.3 ± 0.7 mV K‐1) upon functionalizing its percolated network with ionic polymers like poly(4‐styrenesulfonic acid) (PSS). Further, unlike organic polymer‐based TE systems, VO‐M not only sustains exposure to high temperatures (≈200 °C, 5 min) but also protects the PSS molecules intercalated into its interlayer space. Moreover, V2O5‐based TE materials can self‐repair any damage to their physical structure with the help of a tiny water droplet. Thus, nanofluidic membranes of reconstructed layered materials like VO‐Ms demonstrate vast robustness and great ionic‐TE performance, which can provide a novel platform for scientific studies and futuristic applications.
Functional Textiles with Smart Properties: Their Fabrications and Sustainable Applications
Authors: Zhang Yabin , Xia Xiaohu , Ma Kaikai , Xia Gang , Wu Maoqi , Cheung Yuk Ha , Yu Hui , Zou Bingsuo , Zhang Xiangwu , Farha Omar K. , Xin John H. 
Published: May 2023

AbstractBenefiting from inherent lightweight, flexibility, and good adaptability to human body, functional textiles are attracting tremendous attention to cope with wearable issues in sustainable applications around human beings. In this feature article, a comprehensive and thoughtful review is proposed regarding research activities of functional textiles with smart properties. Specifically, a brief exposition of highlighting the significance and rising demands of novel textiles throughout the human society is begun. Next, a systematic review is provided about the fabrication of functional textiles from 1D spinning, 2D modification, and 3D construction, their diverse functionality as well as sustainable applications, showing a clear picture of evolved textiles to the readers. How to engineer the compositions, structures, and properties of functional textiles is elaborated to achieve different smart properties. All these tunable, upgraded, and versatile properties make the developed textiles well suited for extensive applications ranging from environmental monitoring or freshwater access to personal protection and wearable power supply. Finally, a simple summary and critical analysis is drawn, with emphasis on the insight into remaining challenges and future directions. With worldwide efforts, advance and breakthrough in textile functionalization expounded in this review will promote the revolution of smart textiles for intelligence era.
Electrical Property Enhancement in Orientation‐Modulated Perovskite La‐Doped SrTiO3 Thermoelectric Thin Films
Authors: Zheng Yunpeng , Chen Hetian , Zhou Zhifang , Yang Yueyang , Zou Mingchu , Zhang Wenyu , Wei Bin , Cai Jinghan , Lan Jin‐Le , Yi Di , Nan Ce‐Wen , Lin Yuan‐Hua 
Published: May 2023

AbstractThermoelectric oxide thin films are promising in chip cooling. The issues on the orientation of thin films are essential as they are related to the structures, morphologies, and thermoelectric properties. In this regard, the orientation modulation is conducted on La‐doped SrTiO3 thin films on (LaAlO3)0.3(Sr2TaAlO6)0.7 (LSAT) single crystal substrates. Layer‐by‐layer growth mode is found in (001)‐ and (110)‐ oriented thin films, resulting in few grain boundaries (GBs). In (111)‐oriented films, island growth mode leads to columnar grain boundaries that build up potential barriers for electrons to be strongly scattered and filtered, suppressing electron mobility and increasing effective mass. In addition, the GBs serve as oxygen vacancy diffusion paths when annealing, causing increased carrier concentration and lattice contraction. The weighted mobility of 71.9 cm2 V−1 s−1 and electrical conductivity of ≈600 S cm−1 are realized in the (001)‐oriented film at room temperature. Ultimately, outstanding power factor values of ≈569 µW m−1 K−2 (room temperature) and ≈791 µW m−1 K−2 (573 K) are successfully achieved, outperforming those in polycrystalline ceramics and (111)‐oriented films. This study systematically investigates the influence of grain boundaries and orientations on SrTiO3‐based thermoelectric films, which lays a solid foundation for improving thermoelectric performance in other oxide thin films.
Self‐Folding Graphene‐Based Interface for Brain‐Like Modular 3D Tissue
Authors: Sakai Koji , Teshima Tetsuhiko F. , Goto Toichiro , Nakashima Hiroshi , Yamaguchi Masumi 
Published: May 2023

AbstractElectrophysiology of 3D neuronal cultures is of rapidly growing importance for revealing cellular communications associated with neurodevelopment and neurological diseases in their brain‐like 3D environment. Despite that the brain also exhibits an inherent modular architecture that is essential for cortical processing, it remains challenging to interface a modular network consisting of multiple 3D neuronal tissues. Here, a self‐folding graphene‐based electrode array is proposed that enables to reconstruct modular 3D neuronal tissue and investigate firing dynamics among moduli. A graphene‐sandwiched parylene‐C film self‐folds into a cylindrical structure within which living cells can be encapsulated. Culture of encapsulated cells inside the folded graphene enables to spontaneously construct 3D cell aggregates and ensure firm contact between the graphene surface and encapsulated cells. As the inner graphene surface can be utilized as an electrode, the reliable cell–electrode contact allows for long‐term electrical recording from multiple 3D aggregates. Additionally, the modular network consisting of multiple 3D aggregates exhibits richer firing patterns than a conventional homogenous 2D network, which demonstrates that the approach enables measurements of firing dynamics in complex 3D neuronal networks. The deformable graphene electrode will be a powerful platform for investigating complex cellular communications in brain‐like 3D cultures.