bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine perfusion preservation with hemoglobin based oxygen vesicles alleviate ultrastructural damages in porcine liver donated after cardiac death
Authors: Zin Nur Khatijah Mohd , Bochimoto Hiroki , Kondoh Daisuke , Ishihara Yo , Iwata Hiroyoshi , Shonaka Tatsuya , Obara Hiromichi , Sakai Hiromi , Furukawa Hiroyuki , Matsuno Naoto 
Published: September 2023

AbstractMidthermic machine perfusion (MMP) of post‐circulatory arrest donor liver grafts has the advantage of preserving the functional ultrastructure of hepatocytes in donor grafts. It was reported that oxygenation during MMP reduces portal venous resistance and increases bile production. The MMP with hemoglobin‐based oxygen vesicles (HbV) keeps the lower aspartate aminotransferase level (an indicator of liver injury) and maintains the functional ultrastructure of mitochondria in the hepatocytes. To evaluated differences of ultrastructural damages in donor livers between the MMP with and without HbV, porcine liver grafts after 60 min of warm ischemia were perfused at 22°C for 4 h with or without HbV, and a part of liver grafts were analyzed by transmission electron microscopy (TEM) and osmium‐maceration scanning electron microscopy (OM‐SEM). The remaining grafts were perfused with autologous blood at 38°C for 2 h in an isolated liver reperfusion model (IRM) that mimics the inside of the body after transplantation, and then analyzed by TEM and OM‐SEM. Hepatocytes after MMP had small round mitochondria with rod‐shaped cristae and reticulovesicular rough endoplasmic reticulum (rER) in both HbV(+) and HbV(−) livers. After IRM of HbV(+) livers, the well‐developed lamellar rER was often found in hepatocytes. Liver sinusoidal endothelial cells (LSECs) after MMP contained some large vacuolar structures containing amorphous garbage in the cytoplasm, and their size along with appearance frequency were smaller and lower, respectively, in HbV(+) livers than HbV(−). Oxygenation during the MMP by using HbV suppressed the ultrastructural damages in donor livers, in particular for the LSECs.Research Highlights
Liver sinusoidal endothelial cells after midthermic machine perfusion had large vacuolar organelles with amorphous garbage.
Oxygenation during the perfusion made them less and smaller, ultrastructurally supporting its utility.
Daytime Variation in Kidney Perfusion, Oxygenation, and Sodium Concentration Assessed by Multiparametric MRI in Healthy Volunteers
Authors: Rasmussen Camilla W. , Bøgh Nikolaj , Ringgaard Steffen , Birn Henrik , Vaeggemose Michael , Schulte Rolf F. , Laustsen Christoffer 
Published: September 2023

BackgroundMRI can provide information on kidney structure, perfusion, and oxygenation. Furthermore, it allows for the assessment of kidney sodium concentrations and handling, allowing multiparametric evaluation of kidney physiology. Multiparametric MRI is promising for establishing prognosis and monitoring treatment responses in kidney diseases, but its intraindividual variation during the day is unresolved.PurposeTo investigate the variation in multiparametric MRI measurements from the morning to the evening.Study TypeProspective.PopulationTen healthy volunteers, aged 29 ± 5 without history of kidney disease.Field Strength/Sequence3 T/T1 mapping, blood‐oxygen level dependent imaging, arterial spin labeling perfusion imaging, diffusion weighted imaging, and sodium imaging.AssessmentA multiparametric MRI protocol, yielding T1, R2*, ADC, renal blood flow and renal sodium levels, was acquired in the morning, noon, and evening. The participants were fasting prior to the first examination. Urine biochemical analyses were performed to complement MRI data. The cortex and medulla were analyzed separately in a semi‐automatic fashion, and gradients of total sodium concentration (TSC) and R2* gradients were calculated from outer cortex to inner medulla.Statistical TestAnalyses of variance and mixed‐effects models to estimate differences from time of day. Coefficients of variation to assess variability within and between participants. A P‐value <0.05 was considered statistically significant.ResultsThe coefficients of variation varied from 5% to 18% for proton‐based parametric sequences, while it was 38% for TSC over a day.Data ConclusionMultiparametric MRI is stable over the day. The coefficients of variation over a day were lower for proton multiparametric MRI, but higher for sodium MRI.Evidence Level2Technical EfficacyStage 2
Dietary supplementation of ark clams protects gut health and modifies gut microbiota in d‐galactose‐induced aging rats
Authors: Tong Tao , Guo Jingya , Wu Ying , Sharma Divya , Sangar Madhuri , Sangpreecha Neeracha , Song Doyoung , Unno Tatsuya , Ham Kyung‐Sik , Kang Seong‐Gook 
Published: September 2023

AbstractBackgroundArk clams, a seafood abundant in various nutrients, are widely consumed worldwide. This study aimed to investigate the protective benefits of two common ark clams in Korea, Scapharca subcrenata (SS) and Tegillarca granosa (TG), on gut health in d‐galactose (d‐gal)‐induced aging rats.ResultsThirty‐two Wistar rats (11 weeks old) were randomly allocated into four groups: a CON group (normal diet + saline intraperitoneal (i.p.) injection), a CD group (normal diet + d‐gal i.p. injection), an SS group (normal diet with 5% SS supplementation + d‐gal i.p. injection), and a TG group (normal diet with 5% TG supplementation + d‐gal i.p. injection). After 12 weeks of treatment, histopathological results showed that gut barrier damage was alleviated in rats of the SS and TG groups, as evidenced by increases in mucus layer thickness and goblet cell numbers. Meanwhile, the two groups supplemented with ark clams showed an evident reduction in oxidative stress biomarkers (malondialdehyde and protein carbonyl content levels in the colon) and an increase in the immune‐related factor (immunoglobulin A level in the plasma) in rats. The 16S ribosomal RNA analysis revealed that SS and TG ark clams significantly increased the proliferations of Bacteroidetes at the phylum level and Parabacteroides at the genus level. Additionally, the levels of the three main short‐chain fatty acids in the cecal contents were also significantly increased in the SS and TG groups.ConclusionOur results indicated a potent preventive effect of SS and TG ark clams on d‐gal‐induced gut injury, suggesting that ark clams may be a promising dietary component for intervening in aging. © 2023 Society of Chemical Industry.
Understanding the impacts of intensive student internships at a campus agricultural project
Authors: Biang JoHannah H. , Brooks Shannon O. , Herles Cecilia M. , Borron Abigail S. , Berle David C. , Thompson Jennifer Jo 
Published: September 2023

AbstractCampus agricultural projects (CAPs) are campus farms or gardens where students learn to grow food. With at least 286 CAPs at institutions of higher education across the United States, this study seeks to understand the impact that participation in intensive internships at CAPs has on students and how student experiences align with the missions of CAPs. We used mixed ethnographic methods to collect rich, longitudinal data with 23 students enrolled in semester‐long internships at one particular CAP over the course of three semesters. Drawing on thematic analysis, we identify themes that capture what students are learning and experiencing in these spaces. Results from this study demonstrate that students participating in these internships gain not only agricultural and horticultural skills from hands‐on learning, but also interpersonal skills (i.e., teamwork and communication) and practical skills (i.e., changing a tire). Over the course of the semester, we see students gain confidence from these skills and develop self‐efficacy in their ability to face challenges and tackle new tasks in the future. Notably, students also develop a strong sense of community within these spaces. Finally, although students express a lingering disconnect between their work and its specific contribution to the community, we find that students can gain insights into service and community engagement in a service‐learning focused CAP.
The traditional approach is no longer sufficient
Authors: Lisouski Taras 
Published: September 2023

AbstractOptical coatings play an enormous role both in our daily life and in advanced research. Virtually any optical element – from a simple lens to the ones used in the sophisticated laser systems, space instruments or data transmission cabinets – have optical coatings. New designs of the coatings and new applications require an upgraded and often designed‐from‐scratch technology to meet the continuously growing thin film optical metrology specifications.
So weit das Auge trägt
Authors: Vollmer Michael 
Published: September 2023

ZusammenfassungSichtweiten in der Atmosphäre reichen von wenigen Metern im Nebel bis zu einigen hundert Kilometern bei extrem guten Fernsichtbedingungen. Die zugrundeliegende Physik geht vom Wahrnehmungskontrast aus. Dieser ändert sich mit der Entfernung entlang der Sichtlinie zwischen Objekt und Auge aufgrund von Lichtstreuung und Absorption an den Bestandteilen der Atmosphäre. Dazu kommt bei der Fernsicht die Refraktion, die es erlaubt, auch über den durch die Kugelform der Erde geometrisch bedingten Horizont hinaus zu sehen.
Transient perivascular inflammation of the carotid artery: Ultrasonography and magnetic resonance imaging findings
Authors: Atik Irfan , Atalar Mehmet 
Published: September 2023

AbstractTransient perivascular inflammation of the carotid artery (TIPIC) syndrome is a rare cause of atypical neck pain. The etiology of TIPIC is not fully known and is characterized by transient inflammation around the carotid artery. Ultrasonography (US) and especially magnetic resonance imaging (MRI) are the most important evaluation methods in the diagnosis and follow‐up of the disease. In this article, we report a 25‐year‐old male patient who presented with unilateral neck pain and was diagnosed with TIPIC in the light of his clinical and radiological findings.
Exploring the colour palette of Wasily Kandinsky: The case study of Spitz‐Rund (1925)
Authors: Ricci Chiara , Ponza Valeria , Romano Francesco Paolo , Caliri Claudia , Conti Claudia , Botteon Alessandra , Possenti Elena , Scalarone Dominique , Cardinali Michela , Bassi Alessandra , Abram Sara , Avataneo Luca , Demonte Daniele , Di Iorio Federico , David Melissa , Miliani Costanza , Previtali Angela Fabrizia , Piccirillo Anna 
Published: September 2023

AbstractThe study and conservation of a painting by Wasily Kandinsky, titled Spitz‐Rund and dated to 1925, was carried out at the Centro per la Conservazione ed il Restauro dei Beni Culturali “La Venaria Reale” 2018 and 2021. This work, owned by the Galleria d'Arte Moderna e Contemporanea of Bergamo (GAMeC), was created with oil paints on cardboard, and later glued onto a wooden support. A first phase of the project entailed a thorough scientific investigation of the artist's materials and techniques by means of a multi‐analytical approach, including both non‐invasive and micro‐invasive techniques. The present contribution discusses some of the most relevant results obtained from scientific analyses on Kandinsky's masterpiece. The painting stratigraphy and colour palette were investigated using multispectral imaging, spot XRF and in situ Raman analyses. Micro‐samples were also taken and analysed with FTIR spectroscopy, Py‐GC/MS, optical microscopy and SEM–EDX. Additional investigations using MA‐XRF provided further insight into the distribution of various chemical elements, proving essential to deepen our knowledge of the painting and to integrate the information obtained from other analytical techniques. The study highlighted several similarities between Spitz‐Rund and other Kandinsky's artworks and made it possible to gain a broader understanding of the artist's technique during the Bauhaus period (1922–1933).
On Incremental Pre-processing for SMT
Authors: Bjørner Nikolaj , Fazekas Katalin 
Published: September 2023

AbstractWe introduce a calculus for incremental pre-processing for SMT and instantiate it in the context of z3. It identifies when powerful formula simplifications can be retained when adding new constraints. Use cases that could not be solved in incremental mode can now be solved incrementally thanks to the availability of pre-processing. Our approach admits a class of transformations that preserve satisfiability, but not equivalence. We establish a taxonomy of pre-processing techniques that distinguishes cases where new constraints are modified or constraints previously added have to be replayed. We then justify the soundness of the proposed incremental pre-processing calculus.
Incremental Rewriting Modulo SMT
Authors: Whitters Gerald , Nigam Vivek , Talcott Carolyn 
Published: September 2023

AbstractRewriting Modulo SMT combines two powerful automated deduction techniques (1) rewriting and (2) SMT-solving. Rewriting enables the specification of behavior of systems using rewriting rules, while SMT theories specify system properties. Rewriting Modulo SMT is enabled by combining existing tools, such as Maude and SMT solvers. Search algorithms used for carrying out Rewriting Modulo SMT, however, cannot exploit the incremental solving features available in SMT solvers as they are based on breadth-first search. This paper addresses this limitation by proposing Incremental Rewriting Modulo SMT Theories, which is a syntactical restriction to rewriting rules. This restriction turns out to naturally be used in several applications of Rewriting Modulo SMT, including the verification of algorithms, cyber-physical systems, and security protocols. Moreover, we propose a Hybrid-Search algorithm for Incremental Rewriting Modulo SMT Theories that combines breadth-first search and depth-first search, thus enabling incremental SMT-solving. We demonstrate through a collection of existing benchmarks that the Hybrid-Search algorithm can achieve a 10 times performance improvement in verification times.
Lagrangians manifesting color-kinematics duality in the NMHV sector of Yang-Mills
Authors: Ben-Shahar Maor , Garozzo Lucia , Johansson Henrik 
Published: September 2023

Abstract
Scattering amplitudes in Yang-Mills theory are known to exhibit kinematic structures which hint to an underlying kinematic algebra that is dual to the gauge group color algebra. This color-kinematics duality is still poorly understood in terms of conventional Feynman rules, or from a Lagrangian formalism. In this work, we present explicit Lagrangians whose Feynman rules generate duality-satisfying tree-level BCJ numerators, to any multiplicity in the next-to-MHV sector of pure Yang-Mills theory. Our Lagrangians make use of at most three pairs of auxiliary fields (2, 1, 0-forms) — surprisingly few compared to previous attempts of Lagrangians at low multiplicities. To restrict the Lagrangian freedom it is necessary to make several non-trivial assumptions regarding field content, kinetic terms, and interactions, which we discuss in some detail. Future progress likely hinges on relaxing these assumptions.
Listeria monocytogenes detection on food contact surfaces: suitability of different swab materials
Authors: Hillig Nadja , Hamedy Ahmad , Koethe Martin 
Published: September 2023

AbstractThe high binding capacity of Listeria monocytogenes to food contact surfaces increases the risk of cross-contamination in food. In addition to appropriate cleaning and disinfection procedures, a suitable sampling plan and technique for the earliest possible detection are necessary for prevention. This paper evaluates the sensitivity of 3 swab materials (cotton, viscose and nylon-flocked) for the qualitative and quantitative detection of L. monocytogenes on food contact surfaces (100 cm2). A L. monocytogenes cocktail of 3 serotypes (IIa, IIb and IVb) was applied to stainless steel, polyvinyl chloride, polytetrafluoroethylene and high-density polyethylene surfaces at a concentration of approx. 1.0 × 101-1.0 × 102 CFU/100 cm2 and approx. 4.0 × 104 CFU/100 cm2. The surfaces were sampled after 15 min of incubation by 3 different swabs using the double-swab technique, and then stored for 4 and 24 h until processing. The results of the qualitative and quantitative tests showed a few statistically significant differences in the detectability of L. monocytogenes by different swab materials, which implies that the detection rate of L. monocytogenes on a certain food contact surfaces can be increased by using the respective most suitable swab.
The impact of process parameters and pin-to-shoulder diameter ratio on the welding performance of polycarbonate in FSW
Authors: Vidakis Nectarios , Mountakis Nikolaos , Moutsopoulou Amalia , David Constantine , Nasikas Nektarios K. , Petousis Markos 
Published: September 2023

AbstractThe utilization of friction stir welding (FSW) for the joining of polymers and composites is gaining increasing recognition due to its capabilities. In this study, the weldability of 4 mm thick polycarbonate (PC) plates in FSW is examined. Statistical modeling tools were employed to investigate the effect of four control parameters, i.e., rotational speed, travel speed, weld tool shoulder, and pin diameter, on the geometrical characteristics (residual thickness) of the weld region and the mechanical performance of the weld components under flexural and tensile loads. A screening experimental procedure with an L9 Taguchi was initially performed to calibrate the control parameter levels. During the welding procedure, the temperature profiles were continuously recorded to verify the materials’ solid state. The welding efficiency of the joint was also assessed, with a 90% welding efficiency achieved in the study. The morphological characteristics of the welded zones were assessed through optical and scanning electron microscopy. The samples welded with 4 mm/min travel speed, 10 mm shoulder diameter, 1000 rpm rotational speed, and 3 mm pin diameter had the highest mechanical performance. Overall, a shoulder-to-pin diameter ratio between 2.5 and 3 achieved the best results. The findings provide valuable information for the weld performance optimization of PC sheets, which can be employed successfully in real-life uses.
Graphical abstract
Notes on the conservation threats to the western lesser spot-nosed monkey (Cercopithecus petaurista buettikoferi) in the Bijagós Archipelago (Guinea-Bissau, West Africa)
Authors: Colmonero-Costeira I. , Sá R. M. , Djaló M. L. , Cunha N. , Cunha J. , Minhós T. , Russo I.-R. M. , Bruford M. W. , Costa S. , Ferreira da Silva M. J. 
Published: September 2023

AbstractThe lesser spot-nosed monkey (Cercopithecus petaurista) is a widely distributed West African guenon, which is generally considered less vulnerable to local extinctions than many sympatric primate species. Guinea-Bissau harbours the westernmost populations of the species, which is thought to be very rare or even extinct on the mainland, but to have putative populations on some islands of the Bijagós Archipelago. However, due to a lack of regional studies, baseline information on these insular populations is missing. We collected baseline data on the anthropogenic activities that possibly threaten the long-term conservation of this primate by using non-systematic ethnographic methodologies. The species was reported to be decreasing in number or rare by locals on two of the islands, and we identified two main conservation threats to it: generalised habitat loss/degradation, and hunting. While subsistence hunting has been recorded before in these areas, we report, to the best of our knowledge for the first time for these islands, the presence of a semi-organised commercial wild meat trade. The carcasses of western lesser spot-nosed monkeys were observed being stored and shipped from seaports to be sold at urban hubs (Bissau and Bubaque Island). The effect of commercial trade on the species could be severe, considering the small, naturally occurring, carrying capacities typical of insular ecosystems. The results of this study highlight the importance of understanding the leading social drivers of wild meat hunting of lesser spot-nosed monkeys on the Bijagós Archipelago, and the need to conduct baseline research on these insular populations, for which qualitative and quantitative methods could be combined.
Breast cancer and incidence of type 2 diabetes mellitus: a systematic review and meta-analysis
Authors: Jordt Nanna , Kjærgaard Kasper Aalbæk , Thomsen Reimar W. , Borgquist Signe , Cronin-Fenton Deirdre 
Published: September 2023

Abstract
Purpose
Breast cancer and its treatments may increase the risk of type 2 diabetes (T2D). We conducted a systematic review and meta-analysis to investigate the association between breast cancer and the incidence of T2D overall, and according to breast cancer treatments.

Methods
We searched PubMed, Embase and references of relevant papers for studies on breast cancer, breast cancer treatment, and subsequent T2D risk. Using random-effects models, we calculated effect estimates and associated 95% confidence intervals of the association between breast cancer, adjuvant breast cancer treatments (i.e., endocrine therapy (tamoxifen, aromatase inhibitors, and combined) and chemotherapy), and subsequent T2D. We used funnel plots to assess publication bias.

Results
Among 15 eligible studies, 10 reported on T2D risk after breast cancer, chemotherapy, or endocrine therapy; five studies investigated more than one association. Compared with patients without breast cancer, those with breast cancer and those who received any endocrine therapy had elevated risk of incident T2D (EE = 1.23, 95% CI = 1.13–1.33 and EE = 1.23, 95% CI = 1.16–1.32, respectively). Among breast cancer patients only, the risk of T2D was higher for those who received tamoxifen compared with those who did not receive tamoxifen (EE = 1.28, 95% CI = 1.18–1.38). Due to few studies, analyses investigating T2D risk after treatment with aromatase inhibitors or chemotherapy were inconclusive.

Conclusion
Our findings suggest an elevated risk of T2D in breast cancer survivors, particularly after tamoxifen therapy. Further research is needed to determine the impact of aromatase inhibitors, and chemotherapy on the incidence of T2D after breast cancer.
Implications of the Theory of Basic Human Values for the Second Demographic Transition: Interdependence and Individualism in the Era of Self-Fulfillment
Authors: Smallenbroek Oscar 
Published: September 2023

AbstractI examine the implications of a modern psychological theory of values for the Second Demographic Transition (SDT). The SDT derives its values theory and measurement from Maslow, who noted that resource-rich environments cause value shifts towards personal-focused growth values. However, Maslow has been replaced by the theory of basic human values (TBHV) which distinguishes person and social-focused growth values. This distinction has two important implications for the SDT. First, some individualistic and self-expressive values identified by the SDT are not growth but basic need motivated and therefore functions of resource-poor environments. Second, the TBHV values on interdependence and independence are strongly influenced by gender and reflect preferences for family and care or career. Therefore, these values can be used to address critiques of the SDT based on the stalled gender revolution. I show that distinguishing values as described in the TBHV can be useful for the SDT. I find that benevolence (interdependence) is positively and openness to change (autonomy/stimulation) is negatively related to marriage in the Netherlands using longitudinal panel data and discrete event history models.