bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green human resource management and employee innovative behaviour: does inclusive leadership play a role?
Authors: Shafaei Azadeh , Nejati Mehran 
Published: January 2023

PurposeThis study examines the relationship between green human resource management (green HRM) and employee innovative behaviour. It also investigates the mediating role of job satisfaction to explore the mechanism through which green HRM is related to employee innovative behaviour. Additionally, it examines the moderating role of inclusive leadership to determine the boundary condition of the relationship between green HRM and employee innovative behaviour.Design/methodology/approachThe study used a quantitative research approach using survey and collected 508 responses from full-time employees in Australia.FindingsThe authors have found support for all the hypothesised relationships in the study. Specifically, green HRM is positively related to employee innovative behaviour. This relationship is mediated by job satisfaction and accentuated by inclusive leadership.Originality/valueGreen HRM promotes a green atmosphere in which employees can contribute to a safer and healthier environment. Despite the increasing attention to green HRM in the management literature, little is known about the mechanisms and boundary conditions explaining employees' responses to green HRM.
Carabid beetles have hump‐shaped responses to disturbance and resource gradients within agricultural landscapes
Authors: Muneret Lucile , Ricci Benoit , Vialatte Aude , Aviron Stéphanie , Ducourtieux Chantal , Biju‐Duval Luc , Petit Sandrine 
Published: January 2023

Abstract

Understanding the effects of the huge diversity of cropping systems on local biodiversity is challenging but necessary to implement agroecological systems. Through a functional approach, the translation of cropping systems into resource and disturbance gradients is a promising way to decipher the relationship between cropping systems and biodiversity but has never been implemented for arthropods.

To investigate the contributions of resource and disturbance gradients arising from cropping systems vs environmental context (regional effect, meteorological conditions and landscape characteristics) on beneficial arthropod communities, we used a dataset collected in 60 crop fields from three French areas over a 5‐year period. It includes all farmer interventions, crop sequences, meteorological data, landscape composition and carabid samplings.

We found that environmental context contributed to about 75% of explained carabid variations on average, while resource and disturbance gradients contributed to about 25% of explained carabid variations. The resource and disturbance gradients were particularly important in winter and in the spring preceding the spring–summer period to determine carabid variations.

Moreover, we identified thresholds above which resource and disturbance gradients start being beneficial or detrimental for carabids. For example, increased treatment index in spring decreased the total activity density of carabids during the spring–summer period.

Synthesis and applications. While implementing for the first time a functional approach to understand the effects of different facets of cropping systems on arthropods, our study also allows us to identify periods and thresholds above which specific practices affect carabids. Finally, avoiding bare soils all along the year, keeping pesticide use intensity below the identified thresholds and adopting a wide diversity of tillage strategies at the landscape scale should all contribute to enhance in‐field carabid occurrences and richness.
To be or not to be: The identity work of pharmacists as clinicians
Authors: McDermott Imelda , Astbury Jayne , Jacobs Sally , Willis Sarah , Hindi Ali , Seston Elizabeth , Schafheutle Ellen 
Published: January 2023

AbstractThis study explores how pharmacists legitimise the expansion of their clinical work and considers its impact on pharmacists’ professional identity work. In the context of pharmacy in the English NHS, there has been an ongoing policy shift towards pharmacists moving away from ‘medicines supply’ to patient‐facing, clinical work since the 1950s. Pharmacists are continuously engaging in ‘identity work’ and ‘boundary work’ to reflect the expansion of their work, which has led to the argument that pharmacists lack a clear professional identity. Drawing insights from linguistics and specifically Van Leeuwen's ‘grammar of legitimation’, this study explains how the Pharmacy Integration Fund, a nationally funded learning programme, provides the discursive strategies for pharmacists to legitimise their identity work as clinicians.
Debating the fate of the homemaker: The ERA and the death of the family wage
Authors: Swinth Kirsten 
Published: January 2023

ABSTRACTThis article revisits the campaign to ratify the Equal Rights Amendment (ERA) to the United States Constitution to argue that amendment adversaries fought over the future of women's economic security. Post‐war US economic growth stalled in the 1970s, bringing the family‐wage ideal of male breadwinning and female homemaking down with it. In these unsettled years, how female economic dependence would be addressed was an open question: would it be by propping up male breadwinning, as ERA opponents wanted, or by combining good jobs with fairly compensated domestic labour and government assistance, as supporters believed the ERA promised? A revisionist interpretation of the ERA battle, this article shifts attention from conflict over gender identity and cultural values to economics and capitalist transformation. It examines arguments presented in pamphlets, the media and to Congress about how homemaking women could achieve security in the face of changing economic reality. The ERA's defeat was a Pyrrhic victory for conservatives. The threat to government‐sanctioned male breadwinning appeared to have been vanquished. But the family‐wage system was truly on the rocks, and supporters’ vision of a working‐family norm, with roles based on function, not gender, won out. Without the ERA, however, working mothers shouldered the consequences.
The age of insecuritisation: Insecure young workers in insecure jobs facing an insecure future
Authors: Rydzik Agnieszka , Bal P. Matthijs 
Published: January 2023

AbstractRapid political‐economic changes in recent decades have led to increasingly insecure youth labour markets and the weakening of state protections, resulting in growing precarisation for young people. This article examines how student‐workers from post‐1992 UK universities on zero‐hour contracts in hospitality experience insecuritisation and societal turbulence as a result of continual neoliberal flexibilization of labour markets. It shows how existing personal insecurity—reinforced by limited state protection, inexperience and socio‐economic background—is intensified by the addition of job insecurity, underpinned by transactional employment relations and workplace power asymmetries. It argues that these experiences can further precarisation of already insecure individuals and shape perceptions of future labour market insecurity. Drawing on 35 semi‐structured interviews, the article posits that insecurity is structurally entrenched in the lives of many student‐workers and zero‐hour contract work can further exacerbate it by sustaining existing inequalities, dialling down aspirations and hindering prospects of social mobility.
Reproduction strategy of nocturnal marine molluscs: running for love
Authors: GAO Xiaolong , ZHANG Mo , LIN Shihui , LYU Mingxin , LUO Xuan , YOU Weiwei , KE Caihuan 
Published: January 2023

AbstractThe cost of reproduction is the core driver of life history evolution in animals. This paper demonstrates that the cumulative distance moved and the duration of movement of sexually immature abalones, Haliotis discus hannai, kept in various male and female groups, were significantly higher than those of sexually mature individuals, except when kept in mixed cultures of mature males and females. After mixed‐culture, sexually mature males moved significantly further and for a longer duration than mature female abalones, and even more so than mature male abalones of any other group. Examination of the LC‐MS metabolomics of mature males cultured with sexually mature females (AM) and those cultured with sexually immature females (JM) showed that cyclic adenosine monophosphate (cAMP) acted as a differential metabolic biomarker. After 24‐h uninterrupted sampling, the concentration of 5‐HT and the expression levels of the 5‐HT2 and 5‐HT6 receptors in AM were significantly higher than those in JM. After further injection of 5‐HT2 and 5‐HT6 receptor antagonists, the concentrations of cAMP and PKA rose again, but the cumulative movement duration and distance of male abalones decreased significantly, showing that 5‐HT was involved in the regulation of movement behavior of male abalones through the 5‐HT2 and 5‐HT6 receptor‐activated cAMP‐PKA pathways. The results demonstrated a significant increase in the movement endurance of mature male abalones cultured with mature females, providing a theoretical basis for understanding the adaptive life history strategies of abalones and suggesting ways to protect diverse benthic resources for abalones during the reproductive stage.
Populism à la Carte: The paradoxical political communication of Narendra Modi on Twitter
Authors: Martelli Jean‐Thomas , Jumle Vihang 
Published: January 2023

AbstractHow and where is democracy ‘hacked’? Studies examining the variability of the populist discourse rely on the—often tacit—assumption that global digital platforms are used similarly from one country to the other. By examining political rhetoric on Twitter, we show that populist communication is tailored to a particular audience profile rather than a particular social media (SM). More specifically, we compare Indian Prime Minister Narendra Modi's tweets with his addresses on multiple mediums. We describe how Modi uses wide‐reaching media such as radio to unfold a populist narrative based on institutional disintermediation, layman's language, counselling and the staging of an intimate conversation with the masses. Modi uses more elitist and cosmopolitan SM sites in India, such as Twitter, to mitigate his populist credentials, and introduce himself as a respectable democratic leader favouring multilateral collaborations, banal nationalism and Gandhian peace‐building. The variability of his political rhetoric across seven address formats indicates that Modi is populist tactically rather than ideologically, which complicates the tenets of the dominant ‘ideational’ populist paradigm. To further ground our argument empirically, we venture into comparing Modi's and Trump's tweets. We suggest that due to the popularity of Twitter in the United States, it was strategically useful for the former President of the United States to act populist on the platform, while that is not the case for Modi. This tends to indicate that not enough attention is given to intermedium studies that complement comparisons between states/regions with comparisons nested within a coherent political space.
Assessment of abuse potential of carfentanil
Authors: Wei Jiayun , Lai Miaojun , Li Feng , Chen Yuanyuan , Li Xiangyu , Qiu Yi , Shen Haowei , Xu Peng , Di Bin 
Published: January 2023

AbstractCarfentanil, as a fentanyl analogue, is a potent synthetic opioid. It has been controlled in many countries, and its emergence has been highlighted by many recent reports. However, although discriminative stimulus effects of carfentanil in rats had been reported, its abuse potential has not been fully evaluated. In this study, we evaluated the abuse potential of carfentanil via the tests of conditioned place preference (CPP), drug self‐administration and naloxone‐precipitated opioid withdrawal assay, compared with fentanyl and heroin. Carfentanil exhibited significant place preference at a minimum dose of 1 μg/kg in mice, whereas fentanyl and heroin induced significant place preference at the minimum doses of 100 μg/kg and 1000 μg/kg, respectively. In the drug‐substitution test in heroin self‐administered rats (50 μg/kg/infusion), carfentanil and fentanyl acquired significant self‐administrations above saline levels from 0.05–0.1 and 0.1–10.0 μg/kg/infusion, respectively. Carfentanil induced the maximum number of infusions at 0.1 μg/kg, whereas fentanyl and heroin at 1 and 25 μg/kg, respectively. In short, carfentanil showed the highest potency to induce CPP and self‐administration. Furthermore, repeated treatment with escalating doses of carfentanil, fentanyl or heroin induced typical withdrawal symptoms in mice, including a greater number of jumping and weight loss than saline group. This indicated that carfentanil could produce physical dependence similar to fentanyl and heroin. Taken together, the present study demonstrated the higher abuse potential of carfentanil compared with fentanyl and heroin. The rank order of abuse potential for these compounds is carfentanil > fentanyl > heroin.
Anatomy of the rabbit inner ear using computed tomography and magnetic resonance imaging
Authors: Abd El‐Hameed Zeinab Said , El‐Shafey Anwar Abd El‐Fattah , Metwally Mohamed Attia , Abd El‐Samie Hesham Abd El‐Rahman , Kassab A. 
Published: January 2023

AbstractAnatomically, the inner ear is a highly complex organ of intricate design, composed of a bony labyrinth that encases the same‐shaped membranous labyrinth. It is difficult to study the three‐dimensional anatomy of the inner ear because the relevant structures are very small and embedded within the petrous temporal bone, one of the densest bones in the body. The current study aimed to provide a detailed anatomic reference for the normal anatomy of the rabbit's inner ear. As a study model, ten healthy adults New Zealand White rabbit heads were used. Six heads were used for macroscopic evaluation of the bony and membranous labyrinths. The remaining four heads were evaluated radiographically, where 3D images were generated of the bony and membranous labyrinths using data sets from computed tomography (CT) and magnetic resonance imaging (MRI), respectively. The anatomical structures were identified and labelled according to NominaAnatomicaVeterinaria (NAV). Our study revealed that CT and MRI are the optimal cross‐sectional imaging modalities for investigating such tiny and often inaccessible inner ear structures. As high‐quality scanners are not readily available to veterinarians, the CT and MRI images generated by this research were of lower quality; therefore, high‐quality dissections were used to identify/support structures seen in these images. In conclusion, this study provides one of the first investigations that uses multislice CT scans and MRI to study the rabbit's inner ear and its correlation with the corresponding anatomical images. Both anatomical, CT and MRI images will serve as a reference for interpreting pathologies relative to the rabbit's inner ear.
Effect of di(n‐butyl) phthalate on the blood–testis barrier during puberty onset
Authors: Molele Reneilwe A. , Zakariah Musa , Ibrahim Mohammed I. A. , Mahdy Mohamed A. A. , Fosgate Geoffrey T. , Brown Geoffrey 
Published: January 2023

AbstractDi(n‐butyl) phthalate (DBP) is considered a substance of serious concern because of its reproductive toxicity and endocrine‐disrupting properties. Exposure to DBP causes morphological and functional changes in the male reproductive system of birds and mammals. However, there are no detailed reports on the effects of DBP on the Sertoli cell and junctional complexes of the blood–testis barrier (BTB) in birds. The present study investigated dose‐related ultrastructural changes in Sertoli cells and junctional complexes of the BTB in adult Japanese quail (Coturnix coturnix japonica) exposed to DBP prior to puberty. A total of 25 Japanese quail were used for the study. Exposure to DBP doses of 50, 200 and 400 mg DBP/kg/d caused dose‐related ultrastructural changes in junctional complexes including dilation and separation, while disruption of cytoplasmic membranes and mitochondria was observed in Sertoli cells. There was a significant difference in the sum of vacuoles, vacuole diameter, nuclear width, nuclear length, nuclear area, sum of damaged spherical mitochondria, width of elongated mitochondria and the sum of damaged elongated mitochondria among the five treatment groups (p ˂ 0.05). Prepubertal exposure to DBP at doses of 50, 200 and 400 mg DBP/kg/d for 30 days led to adverse effects in the adult male Japanese quail reproductive system by inducing structural changes in the Sertoli cells and junctional complexes. Such changes might disrupt the BTB and potentially interfere with spermatogenesis. Results indicated that the Sertoli cell is sensitive to DBP exposure and might be an important cellular target for DBP‐induced testicular toxicity.
Staphylococcus aureus causes aberrant epidermal lipid composition and skin barrier dysfunction
Authors: Kim Jihyun , Kim Byung Eui , Berdyshev Evgeny , Bronova Irina , Bin Lianghua , Bae Jaewoong , Kim Seokjin , Kim Hye‐Young , Lee Un Ha , Kim Myoung Shin , Kim Hyunmi , Lee Jinyoung , Hall Clifton F. , Hui‐Beckman Jessica , Chang Yunhee , Bronoff Anna Sofia , Hwang Dasom , Lee Hae‐Young , Goleva Elena , Ahn Kangmo , Leung Donald Y. M. 
Published: January 2023

AbstractBackgroundStaphylococcus (S) aureus colonization is known to cause skin barrier disruption in atopic dermatitis (AD) patients. However, it has not been studied how S. aureus induces aberrant epidermal lipid composition and skin barrier dysfunction.MethodsSkin tape strips (STS) and swabs were obtained from 24 children with AD (6.0 ± 4.4 years) and 16 healthy children (7.0 ± 4.5 years). Lipidomic analysis of STS samples was performed by mass spectrometry. Skin levels of methicillin‐sensitive and methicillin‐resistant S. aureus (MSSA and MRSA) were evaluated. The effects of MSSA and MRSA were evaluated in primary human keratinocytes (HEKs) and organotypic skin cultures.ResultsAD and organotypic skin colonized with MRSA significantly increased the proportion of lipid species with nonhydroxy fatty acid sphingosine ceramide with palmitic acid ([N‐16:0 NS‐CER], sphingomyelins [16:0–18:0 SM]), and lysophosphatidylcholines [16:0–18:0 LPC], but significantly reduced the proportion of corresponding very long‐chain fatty acids (VLCFAs) species (C22–28) compared to the skin without S. aureus colonization. Significantly increased transepidermal water loss (TEWL) was found in MRSA‐colonized AD skin. S. aureus indirectly through interleukin (IL)‐1β, tumor necrosis factor (TNF)‐α, IL‐6, and IL‐33 inhibited expression of fatty acid elongase enzymes (ELOVL3 and ELOVL4) in HEKs. ELOVL inhibition was more pronounced by MRSA and resulted in TEWL increase in organotypic skin.ConclusionAberrant skin lipid profiles and barrier dysfunction are associated with S. aureus colonization in AD patients. These effects are attributed to the inhibition of ELOVLs by S. aureus‐induced IL‐1β, TNF‐α, IL‐6, and IL‐33 seen in keratinocyte models and are more prominent in MRSA than MSSA.
Maternal autonomy and prenatal harm
Authors: Howard Nathan Robert 
Published: January 2023

AbstractThis paper offers an account of why prenatal harms seem particularly objectionable. It identifies structural similarities between key cases of prenatal harm and the recently characterized “all‐or‐nothing” problem from Joe Horton. According to the account defended by the paper, a willingness to parent incurs a duty to protect the fetus from harm. This implication provides independent support for so‐called “voluntarist” or “intentionalist” accounts of parental role obligations, according to which, roughly, a mother's autonomous choice to parent a child suffices for having the obligations distinctive of parenthood toward the child.
Stromal bone marrow fibroblasts and mesenchymal stem cells support acute myeloid leukaemia cells and promote therapy resistance
Authors: Miari Katerina E. , Williams Mark T. S. 
Published: January 2023

The bone marrow (BM) is the primary site of adult haematopoiesis, where stromal elements (e.g. fibroblasts and mesenchymal stem cells [MSCs]) work in concert to support blood cell development. However, the establishment of an abnormal clone can lead to a blood malignancy, such as acute myeloid leukaemia (AML). Despite our increased understanding of the pathophysiology of the disease, patient survival remains suboptimal, mainly driven by the development of therapy resistance. In this review, we highlight the importance of bone marrow fibroblasts and MSCs in health and acute myeloid leukaemia and their impact on patient prognosis. We discuss how stromal elements reduce the killing effects of therapies via a combination of contact‐dependent (e.g. integrins) and contact‐independent (i.e. secreted factors) mechanisms, accompanied by the establishment of an immunosuppressive microenvironment. Importantly, we underline the challenges of therapeutically targeting the bone marrow stroma to improve acute myeloid leukaemia patient outcomes, due to the inherent heterogeneity of stromal cell populations.LINKED ARTICLESThis article is part of a themed issue on Cancer Microenvironment and Pharmacological Interventions. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v181.2/issuetoc
Lenvatinib enhances antitumor immunity by promoting the infiltration of TCF1+CD8+ T cells in HCC via blocking VEGFR2
Authors: Mei Zhibin , Gao Xingxing , Pan Caixu , Wu Qinchuan , Wang Shuai , Qian Junjie , Xu Zhentian , Xu Kangdi , Zhou Lin , Zhen Shushen 
Published: January 2023

AbstractLenvatinib is the favorable treatment for advanced hepatocellular carcinoma (HCC), and it is currently undergoing phase III clinical trials. However, the specific effects of lenvatinib on PD1+ CD8+ T cells in HCC microenvironment have not been systematically studied. Here, we established an orthotopic hepa1‐6 mouse model treated with lenvatinib to investigate CD8+ T cells’ role in the tumor and spleen. We found an increasing proportion of TCF‐1+ in PD1+ CD8+ T cells and proliferation of PD1+ CD8+ T cells after lenvatinib treatment. Meanwhile, lenvatinib treatment upregulated the expression of granzyme B on PD1+ CD8+ T cells both in vitro and in vivo. Lenvatinib activated the endogenous mTOR pathway of exhausted CD8+ T cells, and mTOR pathway blockade eliminated the antitumor effect of lenvatinib and function of PD1+ CD8+ T cells. The effects of the mTOR pathway on PD1+ CD8+ T cells after lenvatinib treatment were mediated by VEGFR2 inhibition. Overall, our work provides insight into the mechanism of lenvatinib's antitumor efficacy through exhausted CD8+ T cells in HCC treatment.