bluuebunny/crossref_metadata_2025_split huggingface dataset:
Animal-based ketogenic diet puts severe anorexia nervosa into multi-year remission: A case series
Authors: Norwitz Nicholas G. , Hurn Michelle , Espi Forcen Fernando 
Published: June 2023

Background: Anorexia nervosa is a devastating condition that increases risk of death over five-fold and is associated with a high rate of relapse. Considering the growing field of metabolic psychiatry, anorexia can be framed as a ‘metabolic-psychiatric’ condition that may benefit from treatment with metabolic health interventions with neuromodulatory properties. Ketogenic diets, very low carbohydrate high-fat diets, are one such neuromodulatory intervention with a long history of use in epilepsy and more recently in other systemic, neurological and mental health conditions.Aim: To describe clinical cases that highlight the potential of ketogenic diets in the treatment of anorexia and the need for further research.Setting: Patient interviews were conducted via telemedicine.Methods: Medical interviews and chart reviews were conducted with three patients with severe anorexia. Written informed consent was provided by all participants.Results: Patients with anorexia, body mass index (BMI) nadirs of 10.7 kg/m2, 13.0 kg/m2 and 11.8kg/m2 and refractory to standard of care therapy, each achieved remission of between 1–5 years to date on a high-fat animal-based ketogenic diet. Patients exhibited not only improvements in weight, with weight gain of over 20 kg each, but also diminution of anxiety and overall enhanced mental well-being.Conclusion: These cases suggest a ketogenic diet may be useful for some patients with anorexia. Further research is needed.Contribution: This case series is the first to document treatment of anorexia with unimodal ketogenic diet intervention and raises provocative questions about the role of this neuromodulatory dietary treatment for patients with anorexia, as well as the neurometabolic nature of the disease itself.
Narrative Review of Systemic Inflammatory Response Mechanisms in Cardiac Surgery and Immunomodulatory Role of Anesthetic Agents
Authors: Maisat Wiriya , Yuki Koichi 
Published: June 2023

ABSTRACT
Although surgical techniques and perioperative care have made significant advances, perioperative mortality in cardiac surgery remains relatively high. Single- or multiple-organ failure remains the leading cause of postoperative mortality. Systemic inflammatory response syndrome (SIRS) is a common trigger for organ injury or dysfunction in surgical patients. Cardiac surgery involves major surgical dissection, the use of cardiopulmonary bypass (CPB), and frequent blood transfusions. Ischemia-reperfusion injury and contact activation from CPB are among the major triggers for SIRS. Blood transfusion can also induce proinflammatory responses. Here, we review the immunological mechanisms of organ injury and the role of anesthetic regimens in cardiac surgery.
Left Main Coronary Artery Aneurysm with Fistula to Superior Vena Cava: A Challenging Case
Authors: Pujara Jigisha , Panda Suvendu , Singh Guriqbal , Harbola Garima , Sachan Pragya , Chhauda Tanya , Vachaparampil Ryan 
Published: June 2023

ABSTRACT
Coronary artery fistulas (CAFs) are rare congenital coronary artery abnormalities, with direct communication between a coronary artery and a cardiac chamber, great vessel or other structure. We report here, a rare case of a 25-year-old male with CAF from the aneurysmal left main coronary artery to the superior vena cava detected on echocardiography and computerized tomography (CT) coronary angiography.
Comparative Study to Assess the Effect of Cartoon Watching and Distraction Card on Physiologic Parameters and Fear Level during Inhalation Therapy in Children
Authors: Jadhav Supriya Suresh , Kevade Harshavardhan Anil , Kadam Harshad Sadashiv , Naregal Prakash Mallikarjun , Mohite Vaishali Rajsinh , Pawar Shivaji Hanamant 
Published: June 2023

Background:
Children are the world’s most valuable resource and its best hope for the future. Distraction is a very common way to distract a child’s attention from a potentially unpleasant procedure, lessen their fear, and help them relax.

Objective:
The objective of this study was to assess the effectiveness of cartoon-watching and distraction cards on physiological parameters and fear levels during inhalation therapy in children.

Materials and Methods:
A quasi-experimental study design was used in this study to monitor 60 children between the ages of 3 and 6 years selected by a simple random sampling method. Each of the cartoon and distraction groups had 30 children. A self-structured demographic performa and a standard Children Fear Scale were used to collect data from children. An unpaired t-test was used to estimate the effectiveness of the cartoon and distraction group among participants receiving inhalation therapy. Using the Chi-square test, the researcher looked at the association between fear and sociodemographic variables.

Results:
The difference between the mean after intervention pulse rates and respiratory rate of both groups was evaluated and it was found statistically significant (P < 0.05). The difference between the mean fear score in the cartoon group and the distraction card group was found to be statistically significant after the inhalation therapy (P < 0.0001).

Conclusion:
It was observed that the cartoon-watching therapy was better than the distraction card therapy in reducing the fear level during inhalation therapy among children. However, cartoon-watching and distraction cards were more significant on physiologic parameters and fear in children during inhalation therapy.
Case Report: Cedecea lapagei Infection: Report of a Case in Peru and Review of the Literature
Authors: Al-kassab-Córdova Ali , Valdiviezo-Polo Patricia , Ulloque-Badaracco Juan R. , Honorio-Arroyo Carlos L. , Hueda-Zavaleta Miguel , Benites-Zapata Vicente A. 
Published: June 2023

ABSTRACT.
Cedecea lapagei is a gram-negative, non-encapsulated, facultative anaerobic bacterium that has been reported in only a few cases with varying clinical presentations, drug susceptibility, and treatment since its first isolation in 1981. This study aimed to describe a case report of C. lapagei in Peru and systematically review the documented case reports of individuals infected with C. lapagei. A 59-year-old man who had become bedridden with Parkinson’s disease and had epilepsy presented with a 1-week history of fever and sore throat and was admitted. Physical examination revealed an obtundation state and abolished vesicular murmur in the right hemithorax. During hospitalization, the patient was diagnosed with various infections, including tuberculosis, for which he received broad-spectrum antibiotics. In the absence of clinical improvement, a urine culture was performed showing C. lapagei (detected by BD Phoenix M50 system, Vernon Hills, IL). The patient received amoxicillin/clavulanate and was discharged. Case reports of C. lapagei were also searched in five databases on January 28, 2023. Twenty cases of C. lapagei were reported worldwide between 2006 and 2022, 16 of which involved adults. Fever was the most common manifestation (75%), and pneumonia was the primary form of presentation (45%). Moreover, 90% of the patients had at least one comorbidity, and 15% died. Also, most of the isolates were sensitive to ciprofloxacin (81%), meropenem (62%), and amikacin (60%). Overall, C. lapagei should be suspected in compromised hosts, particularly those with pneumonia. Although the bacterium can affect various organs and the antibiotic susceptibility pattern is variable, quinolones, tetracyclines, and carbapenems seem to be the first therapeutic option.
Role of serum levels of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in predicting severity of acute appendicitis
Authors: Zülfikaroğlu Barış , Akkurt Gökhan , Akın Merve , Kemal İşman Ferruh , Çınar Yastı Ahmet , Mahir Özmen Mehmet 
Published: June 2023

Objective: One of the most prevalent abdominal crises is acute appendicitis (AA). Clinical diagnosis, even for skilled surgeons, is frequently challenging, as indicated by the high proportion of negative investigations. The purpose of this study was to see if serum TWEAK levels might be used to diagnose acute appendicitis.
Material and Methods: Between June 2017 and May 2019, all patients who had surgery with the original diagnosis of AA were included in the study. TWEAK, WBC, CRP, and bilirubin levels were compared.
Results: The levels of WBC, CRP, and bilirubin were compared to pathology. All three blood indicators increased significantly in AA patients. However, no statistically significant difference in the levels of all three blood indicators was seen between individuals with simple AA and those with severe AA. TWEAK plasma concentrations were considerably greater in patients with severe AA than in the healthy control and NAA groups. TWEAK levels were significantly greater in individuals with severe AA compared to patients with simple AA.
Conclusion: Serum TWEAK levels that are elevated may be used to diagnose acute appendicitis as well as prognostic indicators for the severity of appendicitis.
A retrospective study of diagnosis and management of gallbladder perforation: 10-year experience from a tertiary health care centre
Authors: Wani Ab Hamid , Iqbal Javid , Parihar Satish 
Published: June 2023

Objective: The aim of this study was to perform retrospective analysis of data collected from patients of gallbladder perforations for diagnosis, management and outcome.
Material and Methods: A retrospective analysis of data was carried out for 40 patients of gallbladder perforations from the hospital record of patients who were diagnosed preoperatively and intraoperatively as a case of gallbladder perforation over a period of 10 years and were managed in our surgery unit of a tertiary health care centre. Patients were included irrespective of sex except cases of trauma and patients of the paediatric age group.
Results: Among 40 patients, 26 were females and 14 were males. As per Anderson modification of Neimeier classification, 13 (32.5%) had type 1, 23 (57.5%) had type 2, and four (10%) patients had type 3 perforations and none of the patients had type 4 perforation. Twenty-three patients (57.5%) were found to have fundal perforation, followed by body in 11 patients (27.5%), three (7.5%) in Hartman’s pouch while in three patients (7.5%), there were multiple perforations. All patients of type 1 Neimer classification were diagnosed clinically as cases of biliary peritonitis, whereas most cases of type 2 Neimer classification were diagnosed preoperatively by CECT abdomen 12/23 patients (52%) and ultrasound abdomen 10/23 (43.47%). All patients underwent surgery, and there were three mortalities.
Conclusion: In our study, there was female predominance in patients having gallbladder perforation. Of the patients, 52.5% were diabetic and mean age was 55.9 years. CECT abdomen was the most useful modality for diagnosis of type 2 gallbladder perforations. Timely surgical intervention is mandatory for a better outcome of these cases.
Перспективы изучения химического состава и микробиологического пейзажа сточных вод предприятий
Authors: Аухадиева Э. А. , Аллаярова Г. Р. , Зеленковская Е. Е. , Курилов М. В. , Даукаев Р. А. , Гизатуллина Л. Г. 
Published: June 2023

Целью работы был мониторинг качественного состава сточных вод предприятий г. Уфы. Исследование показало, что сточные воды некоторых предприятий являются загрязненными по содержанию взвешенных веществ, нефтепродуктов, ионов аммония, ХПК. Выявлена значимая корреляция между ХПК и БПК, БПК и содержанием фосфат-ионов, БПК и содержанием ионов аммония, величиной рН и содержанием ионов аммония. Соотношение между показателями ХПК и БПК позволяет судить о составе сточных вод и является подсказкой при подборе наиболее оптимального метода очистки. Несущественная разница между данными параметрами указывает на целесообразность применения биологической очистки, ведь чем больше органики, тем выше показатели БПК. Значительное превышение ХПК, по сравнению с БПК, указывает на большое содержание стойких органических соединений, которые трудно подвергаются биохимическому взаимодействию, и в этом случае правильнее будет использование физико-химических способов очистки. В пробах выделены и идентифицированы грамотрицательные условно-патогенные бактерии семейства Enterobacteriaceae – Escherichia coli, Klebsiella pneumoniae, Salmonella sp., Citrobacter sp., бороться с которыми эффективнее и экологически безопаснее методом ультрафиолетового обеззараживания. Проведенный мониторинг может стать хорошей опорой при подборе наиболее оптимального метода очистки сточных вод.
Reliance of Corrosion Characteristics for Two Iron-Based Alloys on the Water Content in 1-Butyl-3-Methylimidazolium Tetrafluoroborate
Authors: Yan Ying , Li Mengting , Chen Peng , Wang Shuyuan , Shi Chunjie , Zhou Hao , Wu Laiming , Cai Lankun 
Published: June 2023

Although the corrosion of iron-based alloys by ionic liquids (ILs) has been reported, the influence of trace water in ILs on its corrosion mechanism is often ignored. In this work, we investigated the corrosion behavior of Q235 carbon steel (Q235 CS) and 304 stainless steel (304 SS) exposed to 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]BF4) with trace water (0.5 wt% to 4.0 wt%) at 323 K. Electrochemical tests and surface analysis manifested that the increasing water content accelerated corrosion of the two iron-based alloys in [BMIM]BF4. A nontypical passivation zone was observed for Q235 CS, while 304 SS exhibited completely active dissolution and its corrosion situation was not as serious as Q235 CS. The occurrence of pitting corrosion is responsible for 304 SS behaviors in [BMIM]BF4. Some corrosion products accumulated on the surface of both iron-based alloys were similar, including FeF2, FeF3, FeO, Fe2O3, and/or FeOOH. Gas products during corrosion were also monitored to avoid the complicated cathodic depolarization process, and it was found to be composed of BF3, HF, and H2. Finally, the corrosion mechanism of iron-based alloys in ILs with trace water was proposed. The illustrated mechanism would be meaningful for understanding the similar corrosiveness to iron-based alloys.
Women, Slavery, and the Archive: Innovations in Slavery Studies and Contemporary Connections
Authors: Swaminathan Srividhya 
Published: June 2023

“Women, Slavery, and the Archive: Innovations in Slavery Studies and Contemporary Connections”
Early scholarship on slavery, abolition, and the British empire largely ignored the contribution of women of any race to the African Institution. British women who participated in boycotts, produced literary texts against African enslavement, and did the legwork of circulating petitions were relegated to footnotes until well into the twentieth century when women scholars began to create space in the canon for the unrecognized or under-recognized women writers. These new avenues of research evolved through decades to become more inclusive, more critical, and more ground-breaking in bringing the past into the present. I identify four important shifts in our understanding of British enslavement and abolition over the long eighteenth century: 1. recognition of (white) women’s work in the abolitionist campaigns; 2. recognition of the labor of enslaved women and their contributions to resistance; 3. recognition of women’s involvement in supporting as well as resisting slavery; 4. recognition of the erasure of people, and the violence of the archive that only validates recorded experiences. Recovering these various kinds of erasures has opened possibilities for new methods of analysis. The legacy of this work not only opened slavery studies to new methodologies of gender and intersectional analyses, but it also opened the archive to productive critique. The new avenues for slavery studies recovers the voices of silenced women and empowers scholar who wish to challenge established narratives. By reviewing the scholarly legacy of transatlantic slavery studies, we can also better appreciate the influence on the immediate present. Contemporary work on Black Lives Matter (abolition), 1619 Project, and the attempts to ban critical race theory address the importance of the transitions in scholarship and how their legacies can reshape the future.
It’s a Wonderful Life
Authors: Newton Michael 
Published: June 2023

Frank Capra's It's a Wonderful Life is one of the best-loved films of Classical Hollywood cinema, a story of despair and redemption in the aftermath of war that is one of the central movies of the 1940s, and a key text in America’s understanding of itself. This is a film that remains relevant to our own anxieties and yearnings, to all the contradictions of ordinary life, while also enacting for us the quintessence of the classic Hollywood aesthetic. Nostalgia, humour, and a tough resilience weave themselves through this movie, intertwining it with the fraught cultural moment of the end of World War II that saw its birth. It offers a still compelling merging of fantasy and realism that was utterly unique when it was first released, and has rarely been matched since.
Michael Newton's study of the film investigates the source of its extraordinary power and its long-lasting impact. He begins by introducing the key figures in the movie’s production - notably director Frank Capra and star James Stewart - and traces the making of the film, and then provides a brief synopsis of the film, considering its aesthetic processes and procedures, touching on all those things that make it such an astonishing film. Newton's careful analysis explores all those aspects of the film that are fundamental to our understanding of it, particularly the way in which the film brings tragedy and comedy together. Finally, Newton tells the story of the film’s reception and afterlife, accounting for its initial relative failure and its subsequent immense popularity.
Point Blank
Authors: Wilson Eric G. 
Published: June 2023

John Boorman’s Point Blank (1967) has long been recognised as one of the seminal films of the sixties, with its revisionary mix of genres including neo-noir, New Wave, and spaghetti western. Its lasting influence can be traced throughout the decades in films like Mean Streets (1973), Reservoir Dogs (1992), Heat (1995), The Limey (1999) and Memento (2000).
Eric Wilson’s compelling study of the film examines its significance to New Hollywood cinema. He argues that Boorman revises traditional Hollywood crime films by probing a second connotation of ‘point blank’. On the one hand, it is a neo-noir that aptly depicts close range violence, but, it also points toward blankness, a nothingness that is the consequence of corporate America unchecked, where humans are reduced to commodities and stripped of agency and playfulness.
He goes on to reimagine the film’s experimental style as a representation of and possible remedy for trauma. Examining Boorman’s formal innovations, including his favouring of gesture over language and blurring of boundaries between dream and reality, he also positions the film as a grimly comical exploration of toxic masculinity and gender fluidity.
Wilson’s close reading of Point Blank reveals it to be a film that innovatively inflects its own generation and speaks powerfully to our own, arguing that it is this amplitude, which encompasses the many major films it has influenced, that qualifies the film as a classic.
Pelaksanaan Pendidikan Informal Pada Keluarga Suku Anak Rimba di Kampung Kelukup Dusun Dwi Karya Bhakti Kabupaten Bungo
Authors: Sungkowo  , Saputra Yahya 
Published: June 2023

Secara umum hampir 90 % anak rimba tidak memperoleh pendidikan formal dikarenakan tekanan mental dan sosial. Penelitian ini menggunakan pendekatan kualitatif disekripdif dengan teknik observasi, wawancara dan dokumentasi. Permasalahan yang diteliti meliputi: 1) Bagaimana sistem pendidikan informal yang dilakukan oleh masyarakat suku anak rimba di kampung Kelukup Dusun Dwi Karya Bhakti Kecamatan Pelepat Kabupaten Bungo, 2) kendala yang dihadapi oleh masyarakat suku anak rimba dalam melaksanakan pendidikan informal bagi putra-putrinya, 3) Upaya yang dilakukan oleh masyarakat suku anak rimba dalam melaksanakan pendidikan informal bagi putra-putrinya. Hasil penelitian ini sebagai berikut: 1) Sistem pendidikan informal yang dilakukan oleh masyarakat suku anak rimba di kampung Kelukup Dusun Dwi Karya Bhakti meliputi: a) pendidikan besale (perenungan diri dalam proses pengobatan), b) pendidikan berburu, c) pendidikan menghafal mantra, 2) Kendala yang dihadapi oleh masyarakat suku anak rimba dalam melaksanakan pendidikan informal bagi putra-putrinya meliputi: a) kendala strata sosial yang jauh berbeda dengan masyarakat umum menjadi pemyebab mindernya suku anak rimba dalam berinteraksi, b) sikap pesimis yang melekat pada suku anak rimba menjadi penyebab mereka tetap terisolir, 3) Upaya yang dilakukan oleh masyarakat suku anak rimba dalam melaksanakan pendidikan informal bagi putra-putrinya adalah: a) program kerjasama pada persamaan hak dan kewajiban warga Negara, b) program pemberdayaan prempuan, c) program Keluarga Berencana, d) program majelis taklim, e) program pelayanan kesehatan Ibu dan Anak, f) program bina keluarga sejahtera.
Studi Etnofarmasi Tumbuhan Berkhasiat Obat Pada Suku Dayak Di Desa Sungai Bawang Muara Badak Kalimantan Timur
Authors: Dian Kurniawan Fredy , Hamzah Hasyrul , Yudhawan Indra , Nurfitriani A. , Abbas Al Fajri Badrani , Maulana Riza , Mochtar Chaerul Fadly , Fajrianti Nila , Pratama Virgiawan Yoga 
Published: June 2023

Latar Belakang: Tanaman obat masih sering digunakan untuk pengobatan secara tradisional oleh warga yang hidupnya bergantung pada alam seperti Suku Dayak di desa Sungai Bawang Muara Badak. Tujuan dari penelitian ini untuk mengetahui penggunaan tanaman obat apa saja yang digunakan oleh Suku Dayak di Desa Sungai Bawang Muara Badak Kalimantan Timur sebagai pengobatan tradisional.

Metode: Penelitian ini merupakan penelitian deskriptif yang menggunakan metode kualitatif. Teknik pengambilan sampel yakni snowball sampling.. Teknik pengambilan data yang digunakan dalam penelitian ini adalah observasi, angket, dan dokumentasi. Jumlah responden dalam penelitian ini sebanyak 12 warga yang mengetahui dan memanfaatkan tumbuhan obat di Desa Sungai Bawang Muara Badak Kalimantan Timur.

Hasil: Hasil penelitian yang diperoleh yaitu terdapat 20 jenis tanaman obat dari 12 responden yang telah diwawancarai, dan juga nama lokal atau nama tumbuhan, bagian yang digunakan untuk pengobatan, metode pengolahan tumbuhan obat dan cara penggunaan tanaman sebagai obat.

Kesimpulan: Tanaman obat yang digunakan oleh Suku Dayak di Desa Sungai Bawang berjumlah 20 jenis tanaman yang digunakan untuk pengobatan tradisional. Bagian yang dimanfaatkan warga Suku Dayak di Sungai Bawang untuk pengobatan adalah bagian batang, daun, rimpang dan umbi.

Kata kunci: Masyarakat Suku Dayak Desa Sungai Bawang; Obat tradisional; Tumbuhan obat; etnofarmasi