bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phenotypic characteristics and factors associated with Assaf lamb body weight and morphology
Authors: Aljamaeen Azzam K. J , Tabbaa Mohammad J , Al-Atiyat Raed M. , Titi Hosam H. 
Published: August 2023

Abstract

The phenotypic characteristics of animals are result of the complex interaction of a number of genetic and non-genetic factors, which usually act simultaneously and it is difficult to determine the degree of influence of each of them. The goal of this study was to describe Assaf lamb morphology and its relationship with body weight (BW) at various ages, which had not previously been described in Jordan, and only adult Assaf had been described globally. BWs and phonotypical characteristics measurements were taken on 405 lambs, 208 lambs at birth (within three days of birth), 96 lambs at weaning (around 60 days), and 101 lambs at marketing age (around 120 days). The measurements were; withers height (WH), body length (BL), chest girth (CG), chest depth (CD), head length (HL), head width (HW), rump length (RL), RW (RW), shoulder width (SW), shin circumference (SC), foreleg height (FLH), rump height (RH) and rear leg height (RLH). Month of birth (MO) significantly (P < 0.001) affected BW and all morphological characteristics except CD and RW at birth. At weaning BW weight, HL, CG, RL, CD, SW, and RW were significantly (P < 0.001) affected by MO. MO has an effect on BW, HW, CG, SC, BL, RL, CD, SW and RW. Factors such as the sex of the lamb, birth type, and dam age significantly affected different morphological characteristics. Furthermore, BW was positively correlated with different morphological characteristics at different ages. On the other hand, equations were developed to predict BW at birth, weaning, and marketing based on various morphological characteristics while taking high into account.
The effect of craniocervical atherosclerotic stenosis on the occurence of neurologic deterioration of patients with small vessel occlusion stroke and their clinical outcomes
Authors: Han Wei , He Yue , Shao YuanWei , Sibomana Pacifique , Yang Yi , Yu Ming 
Published: August 2023

Abstract

Objective
To explore the effect of craniocervical atherosclerotic stenosis (AS) on the occurrence of ND in SVO stroke patients and on the outcomes of patients with SVO stroke with ND (SVO-ND).
Methods
Patients with SVO stroke were consecutively enrolled. AS was defined as a craniocervical artery with a stenosis of ≥ 50% caused by atherosclerosis.
Results
The presence [adjusted odds ratio (aOR) = 2.75, 95% confidence interval (CI) = 1.25–6.07, p = 0.012] and the number of craniocervical AS (aOR = 2.16, 95% CI = 1.33–3.49, p = 0.002) were associated with the occurrence of ND in patients with SVO stroke, respectively. Compared with those with none craniocervical AS, the risk of ND increased in SVO stroke patients with multiple AS (aOR = 6.56, 95% CI = 2.05–21.01, p = 0.002), and the risk of poor outcome increased in SVO-ND patients (aOR = 47.75, 95% CI = 1.66–375.17, p = 0.024).
Conclusion
An evaluation of the craniocervical AS number is a stratification of ND for SVO stroke patients, and a stratification of poststroke disability for SVO-ND patients.
Cognitive deficits in clinical high risk, genetically at high-risk for psychosis and patients with first-episode schizophrenia
Authors: 董 芳 , Mao Zhen , Wang Lu , Bo Qijing , Li Feng , Wang Chuanyue 
Published: August 2023

Abstract
Background: Cognitive deficits are core characteristics of schizophrenia, which precedes the emergence of psychotic symptoms. Clinical high risk for psychosis (CHR) individuals and genetically high-risk of psychosis (GHR) individuals also exhibit cognitive impairments, but it is not clear which domains of cognitive impairments in these two groups were more similar to those of schizophrenia patients. Moreover, it is not clear whether quality factors contribute to this impairment or the disease state causes it. This study aims to explore the cognitive impairments profiles in CHR, GHR and patients with first episode schizophrenia (FES).
Method: We compared the cognitive functions of three groups and a healthy control group (HCs) using the MATRICS Consensus Cognitive Battery (MCCB). Our sample consisted of 56 patients with FES, 42 individuals at CHR, 26 individuals at GHR, and 62 HCs.
Results: Individuals with FES, GHR, and CHR showed significant impairment in most MCCB domains, with the exception of visual learning, when compared to the HCs. None of the MCCB domains were able to accurately distinguish between CHR and GHR individuals. GHR and CHR individuals had intermediate scores between FES and HCs on the domain of processing speed and attention. However, the impairment levels in working memory and verbal learning were similar across all three groups. The CHR performance in social cognition was comparable to that of the HCs, whereas there was no significant difference in problem-solving scores between the GHR and HC groups.
Conclusion: Our findings suggest that significant cognitive deficits exist in CHR, GHR, and FES individuals, and these deficits vary across domains. Cognitive impairment may be a key feature of individuals with schizophrenia, with processing speed and attention potentially serving as reliable markers for identifying those at risk for psychosis. The damage of reasoning/problem solving may be qualitative trait, while as social recgnition may be state characteristic of schizophrenia.
Validation of the Assessments of Adult Health Literacy: A Rasch Measurement Model Approach
Authors: Fleary Sasha A. 
Published: August 2023

Abstract

Background: Both the World Health Organization and U.S. Department for Health and Human Services have emphasized the importance of health literacy (HL) to improving population health and reducing health disparities. HL includes three core areas/qualities: functional (i.e., health-related reading, writing, and numeracy), interactive/communicative (i.e., skills for interacting with multiple constituents and sources of information and navigating the health environment), and critical (i.e., personal and community advocacy for health). HL is implicated in medical adherence, preventive health, mental health stigma and help-seeking, and health decision-making. Though HL is critical to health and health decision-making, research on HL is still relatively limited, with most research focusing on functional HL. A major gap in research is related to the lack of measurement of interactive and critical HL. To address this gap, this study modified and assessed the validity of the Assessments of Adolescent Health Literacy (AAHL-Adolescent), test-based assessments of adolescents’ functional, interactive, and critical HL, in an adult sample.
Methods: One item from the AAHL-Adolescent item bank was modified to be more appropriate for an adult sample. Adults (n=2346) completed a measurement battery that included the HL item bank (12 functional, 15 interactive, and 9 critical HL questions), Newest Vital Sign (NVS), Single-Item Literacy Scale (SILS), demographics, and questions about HL-related behaviors. The assessments were evaluated and validated using Rasch measurement models. Convergent and criterion validity were assessed.
Results: The final 7-item functional, 10-item interactive, and 7-item critical HL assessments and their composite (24 items) fit their respective Rasch models. Item-level invariance was established for gender, ethnicity, education, and age across all assessments. Differential item functioning for race was noted for two items on the interactive HL assessments. Good convergent validity with the NVS and SILS and good criterion validity with the HL-related behaviors were observed for all assessments.
Conclusions
The AAHL-Adult is the first test-based instrument validated in the U.S. that includes assessments for all three core qualities of HL. These assessments have utility across multiple settings, including public health program planning and evaluation, intervention development and evaluation, and clinical settings.
Small molecules DAPT and Forskolin enhances ganglion cells expression in porcine retinal progenitor cells
Authors: Singh Deepti , Dromel Pierre , Rajkumar Jeevan , Maddison Michael , Young Michael 
Published: August 2023

Abstract
Background
Retinal ganglion cell (RGCs) loss underlies several retinal degenerative diseases, including Glaucoma and NF1-OPG. RGCs are essential cells in the visual pathway. These cells transmit the signal gathered from the retinal photoreceptors to the brain via the optic nerve and loss of these cells leads to permanent loss of vision. Presently there is no treatment, however, in the last decade cell replacement has shown potential to restore vision in these conditions.
Materials and Methods
In this study, we have established protocol with a dose dependent response differentiating porcine retinal progenitors (pRPCs) into retinal ganglion cells (RGC) with DAPT and Forskolin treatments. Cells were initially treated with a known concentration of DAPT and Forskolin that has been widely used to culture RGCs.
Results
We identify the optimal concentration and time course that yields the highest expression of RGCs, pRPCs were cultured for 4 weeks in 25 different concentrations of small molecules. At week 2 and 3 approximately 40% of the pRPCs population expressed the neuronal marker TUJ1 and RGCs markers such as RBPMS and Thy1.1. Differentiated cells showed the lowest proliferative index as indicated by Ki-67 expression.
Conclusion
This data demonstrates that specific concentrations of DAPT and Forskolin can induce RPCs to undergo differentiation into RGCs linage.
Overexpression of SAV111 in Streptomyces avermitilis increases avermectin production by binding to aveA1 gene promoter
Authors: Luo Shuai , Zhu Jianya , Zhang Hucheng , Zhu Hua , Wang Xiaowen , Zhang Rong , Wang Xiaojie , Liu Linying , Deng Lina 
Published: August 2023

Abstract

Background
Avermectin antibiotics from Streptomyces avermitilis are used widely in medicine and agriculture. The LuxR family transcription regulators modulate antibiotic biosynthesis in addition to regulating virulence factor expression, biofilm formation, and the hosts′ immune response. At present, there was no report about the regulation of LuxR family proteins on avermection production.
Results
We investigated the mechanism by which overexpression of SAV111, a LuxR family regulator, promoted avermectin production. Shaking flask fermentation of the SAV111 overexpression strain verified that SAV111 promotes avermectin biosynthesis, and indicated SAV111 stimulates cell growth. Streaking experiments showed earlier emergence of morphological differentiation of the SAV111 overexpression strain. Electrophoretic mobility shift assays indicated that SAV111 mainly affects avermectin production by binding to the promoter region of aveA1, a type I polyketide synthase gene in the avermectin biosynthesis pathway.
Conclusions
Results from this work showed that SAV111 promotes avermectin production, cell growth and morphological differentiation in S. avermitilis. Overexpression of SAV111 improves avermectin production mainly by promoting aveA1 transcription. Our findings will expand the regulation network of avermectin biosynthesis and provide a theoretical basis for constructing high-yield strains.
Flashback to a War Zone: A Qualitative Analysis of Black Women’s Experiences During the Racial Pandemic
Authors: Williams Tiffany R. , Erving Christy L. , Bass Jeffery E. , Mitchell Taeja , Martin Reniece , Blasingame Miaya , Hotz Allison 
Published: August 2023

Abstract

The pandemic in 2020 commenced a particularly turbulent era of racial unrest, social injustice, and violence toward Black women. Drawing from Black feminist and intersectionality theories, this qualitative inquiry explored Black women’s experiences of racism and sexism during the racial pandemic. Two hundred forty-one Black women shared their narratives and reflections. The analysis revealed two major themes: 1) racialized violence and harassment (e.g., stereotypes, dominance) and 2) their psychological consequences (e.g., anxiety, depression, racial trauma). Clinical implications are offered to support and empower Black women.
Potentially toxic elements in consumed indoor shrimp farming associated with diet, water and sediment levels: bioaccumulation in head and body tissues in relation to biometric parameters
Authors: Ramos-Miras José Joaquín , Sanchez-Muros Maria Jose , Renteria Patricio , de Carrasco Carlos Gil , Roca-Perez Luis , Boluda-Navarro Mireia , Pro Javier , Martin Jose Antonio Rodriguez 
Published: August 2023

Abstract

Shrimp production is an important industry for many countries and shrimp consumption is increasing worldwide. Shrimps are a highly nutritional food, but can pose a risk for human health if subject to high levels of environmental contaminants. This work studies the presence of As, Cd, Co, Cr, Cu, Hg, Ni, Pb and Zn in shrimps from Ecuador and compares them to such contents noted in other shrimp-production areas in the world to evaluate the possible risks associated with these elements for consumer health, and to relate them to PTEs contents in water, sediments and diets, and also to animal biometric parameters. The PTEs levels (mg kg− 1DM) obtained are: in the head: As (3.52–6.11), Cd (0.02–0.10), Co (0.14–0.49) Cr (0.23–4.89), Cu (99.9–233.0), Ni (0.52–1.86), Pb (0.24–1.09), Zn (51.8-100.5) and Hg (µg kg− 1DM )(10.00-66.81); in the tail: (0.91–3.21), Cd (0.01–0.02), Co (0.01–0.43) Cr (0.01–6.52), Cu (20.0-72.44), Ni (0.15–2.03), Pb (0.01–0.69), Zn (31.2–66.1) and Hg (µg kg− 1DM)(10.00-67.18). The concentration of all the PTEs is generally lower than the limits set for seafood by European regulations, except for As in the cephalothorax (4.63 mg kg− 1). Different behaviour for PTEs accumulation in shrimps was found, which preferentially tend to accumulate in the cephalothorax, except for Hg (40.13 µg kg− 1DM), which accumulates in muscle (body) and is associated with contents of proteins, lipids and total shrimp weight. Nonetheless, the Target Hazard Quotient (THQ) values for PTEs indicate that the consumption of shrimp muscles from Ecuador does not pose a human health risk because the values of these indices are below 1 in all cases.
Association of exposures to serum terpenes with the prevalence of dyslipidemia: a population-based analysis
Authors: Ba Yanqun , Guo Qixin , Meng Shasha , Tong Guoxin , He Ying , Guan Yihong , Zheng Beibei 
Published: August 2023

Abstract
This study sought to examine hitherto unresearched relationships between serum terpenes and the prevalence of dyslipidemia. Serum terpenes such as limonene, α-pinene and β-pinene from the 2013–2014 National Health and Nutrition Examination Survey (NHANES) were used as independent variables. Continuous lipid variables included total cholesterol [TC], high-density lipoprotein cholesterol [HDL-C], non-HDL-C, triglycerides [TG], low-density lipoprotein cholesterol [LDL-C], residual cholesterol [RC], and apolipoprotein B [Apo B]. Binary lipid variables (elevated TC, ≥ 5.18 mmol/L; lowered HDL-C, < 1.04 mmol/L in men and < 1.30 mmol/L in women; elevated non-HDL-C, ≥ 4.2 mmol/L; elevated TG, ≥ 1.7 mmol/L; elevated LDL-C, ≥ 3.37 mmol/L; elevated RC, ≥ 1.0 mmol/L; and elevated Apo B, ≥ 1.3 g/L) suggest dyslipidaemia. Serum terpene relationships with lipid variables were investigated using multivariate logistic and weighted quantile sum (WQS) regression. The study for TC, HDL-C, and non-HDL-C included a total of 1,621 people, whereas the analysis for TG, LDL-C, RC, and Apo B comprised 761 participants. We found that tertiles of serum terpene were positively associated with binary (elevated TC, non-HDL-C, TG, LDL-C, RC, Apo B, and lowered HDL-C) and continuous (TC, non-HDL-C, TG, LDL-C, RC, and Apo B, but not HDL-C) serum lipid variables. There was no significant correlation between serum α-pinene tertiles and elevated Apo B. A WQS regression analysis revealed that all serum lipid variables were linked with a blend of three serum terpenes. According to our data, the prevalence of dyslipidemia was correlated with serum concentrations of three terpenes both separately and collectively.
The propagation path of Chinese traditional culture in Korea based on artificial intelligence technology
Authors: Piao Shuying 
Published: August 2023

Abstract
In order to optimize the dissemination effect of traditional Chinese culture in South Korea, this paper studies the propagation path of traditional Chinese culture in South Korea based on artificial intelligence technology, and proposes a method for external dissemination of traditional Chinese culture based on artificial intelligence technology. This method takes the network path of culture spreading to Korea as the research core, uses a cultural resource reduction method based on Manhattan distance, reduces traditional cultural resources in the network propagation path, and optimizes the setting of support vector machine parameters through improved Sparrow algorithm to extract excellent traditional cultural resources in a classified manner; A communication model based on the recommendation of excellent traditional cultural resources is used to recommend excellent traditional culture of interest to Korean users in the form of excellent cultural resources recommendation, and optimize the dissemination effect of Chinese traditional culture in Korea. After testing, this method can improve the proportion of excellent resources in the dissemination of traditional Chinese cultural resources in South Korea, and optimize the dissemination effect of traditional culture in South Korea.
Resolving Electron and Hole Transport Properties in Semiconductor Materials by Constant Light Induced Magneto Transport
Authors: Musiienko Artem , Yang Fengjiu , Gries Thomas William , Frasca Chiara , Al-Ashouri Amran , Sağlamkaya Elifnaz , Lang Felix , Kojda Danny , Huang Yi-Teng , Hoye Robert , Ahmadi Mahshid , Kanak Andrii , Abate Antonio 
Published: August 2023

Abstract
The knowledge of minority and majority charge carrier properties allows for tailoring the design of semiconductor devices and controlling the performance of solar cells, transistors, detectors, sensors, and LEDs. At the moment, the detection of minority and majority charge transport properties is challenging which limits the accelerated development of existing and the discovery of new materials and material structures. In this work, we developed the Constant Light Induced Magneto Transport (CLIMAT) method which resolves electron and hole mobility, lifetime, diffusion coefficient and length, and quasi-Fermi level splitting. We demonstrate the implication of the CLIMAT for two different semiconductor materials used in solar cells - silicon and metal halide perovskite (MHP). We resolve the transport properties of electrons and holes by combing with light soaking, electrical current, and magnetic field in the CLIMAT method, which predicts the material's effectiveness for solar cell application without making the full device. The accessibility of fourteen material parameters paves the way for in-depth exploration of causal mechanisms limiting the efficiency and functionality of both existing and novel material structures. To demonstrate CLIMAT's broad applicability across the material science community, we further characterized twelve materials with drift mobilities spanning from 10-3 to 103 cm2V-1s-1 and lifetimes varying between 10-9 to 10-3 seconds. The universality of CLIMAT highlights its potential to advance optoelectronic devices and materials in various technological fields.
The impact of producer services agglomeration on the industrial structure upgrading: Evidence from the four urban agglomerations in China
Authors: Li Hai-yan , Chen Yin-zhong 
Published: August 2023

Abstract
According to different agglomeration patterns of producer services, the paper empirically tests the impact of producer services agglomeration on industrial structure upgrading by using the data of 59 prefecture level cities in China's four major urban agglomerations from 2005 to 2018. The results show that producer services agglomeration in the four urban agglomerations has a significant impact on industrial structure upgrading, and the robustness test show that the research conclusion is reliable, but the impact effects of different agglomeration patterns on industrial structure upgrading are different. Specifically, producer services specialization agglomeration has a "U" shaped effect on industrial structure upgrading, while diversification agglomeration has an inverted "U" shaped effect on industrial structure upgrading. The unbalanced economic development between urban agglomerations determines that there are differences in the impact of producer services agglomeration on industrial structure upgrading. Therefore, the paper further empirically tests the impact of producer services agglomeration on industrial structure upgrading from a regional perspective. The results show that the impact of producer services agglomeration on industrial structure upgrading shows obvious regional differences in action direction, action stage and extreme point, et al. Basing on the conclusions of the research, the paper puts forward relevant policy suggestions to accelerate the industrial structure upgrading of China's four major urban agglomerations from the aspects of accelerating the agglomeration development of producer services and formulating differentiated development strategies.
Direct bandgap emission from strain-doped germanium
Authors: Luo Jun-Wei 
Published: August 2023

Abstract
Drawing inspiration from the significant expansion of Ge volume upon lithiation as a Li-ion battery anode, here, we propose to incorporate Li atoms into the Ge lattice to achieve the desired tensile strain for the transition from an indirect to a direct bandgap. Our first-principles calculations show that a minimal amount of 3 at.% Li can convert Ge from an indirect to a direct bandgap, exhibiting a dipole matrix element comparable to that of typical direct bandgap semiconductors. To enhance compatibility with CMOS technology, we additionally suggest implanting noble gas atoms. We also demonstrate the tunability of the direct-bandgap emission wavelength, enabling coverage of the mid-infrared to far-infrared spectrum through the manipulation of dopant concentration. This novel Si-based light-emitting approach presents exciting prospects for surpassing the physical limitations of silicon technology in the field of photonics.
Ruptured Abdominal Aortic Aneurysm discovered by Pocket-sized ultrasound in low resource settings: A case report
Authors: Alasasfeh Ihab , Abudawood Rawan , Hwidi Bayan E. , Al-Shami Raghad 
Published: August 2023

Abstract
Introduction:
While AAA is a life-threatening condition that manifests suddenly in the Emergency department less is known about the use of hand-held ultrasound to diagnose it, especially in low-resource settings.
Case presentation:
A 78-year old man whose a known case of hypertension, the family reported he complained of severe loin pain then he collapsed at home, upon arrival to the ED patient was unconscious with unrecordable BP, pulses were intact, rapid sequence intubation (RSI) was done, ECG showed no ischemic changes, a few seconds later the patient becomes pulseless 1 cycle of CPR was done and the patient reverted to sinus rhythm then he was started on noradrenaline immediately, a few minutes later the lower limbs were noted to be paler and colder than upper limbs raising the suspicion of ruptured AAA, point of care US was done using hand-held ultrasound connected to a tablet, the ultrasound showed a ruptured AAA around 8 cm with intimal flap, surgical intervention was not available because of vascular surgery unavailability at that time, the patient becomes pulseless again CPR was initiated with no response despite the blood-transfusion, finally death was announced.
Discussion and conclusion:
Ruptured AAA is considered a vascular surgical emergency with a very high mortality rates, this case report highlights the importance of POCUS in emergency departments especially the cheaper models of hand-held ultrasound probes.