bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fluctuations of immigration salience: testing alternative explanations of policy salience among US Latinos
Authors: Gomez-Aguinaga Barbara , Morín Jason L. , Sanchez Gabriel R. 
Published: February 2023

AbstractWhat makes immigration a salient issue among Latinos? We focus on immigration – one of the most pressing issues facing the United States (US) – and evaluate the factors that motivate immigration salience among Latinos over several election cycles. Although immigration policy has been linked with the Latino electorate over the period of our study due to high foreign-born rates and mixed-status families within this community, immigration policy has actually not been the dominant issue for the majority of Latino voters over this time period. Using survey responses from the 2008, 2012 and 2016 elections, we test multiple theories of issue salience by exploring social, political and individual determinants of policy salience among Latino voters. We find that in addition to nativity, consumption of ethnic media and group identity are associated with reporting immigration as a salient issue. These findings provide a valuable addition to literature of public opinion on immigration and the origins of policy issue salience among ethno-racial minorities in the US.
Robotic spray painting path planning for complex surface: boundary fitting approach
Authors: Wu Hongrui , Tang Qing 
Published: February 2023

AbstractCurrently, most of the robot path planning methods for spray painting are based on slicing the Computer-Aided Design model of the target surface to generate a series of path points. They usually neglect the geometric boundary of the model and the smoothness of the generated path, leading to a non-uniform coating thickness. To ameliorate it, an improved “boundary fitting approach” is proposed. In this method, the upper and lower boundaries of the target surface are firstly detected based on the topology of the stereolithography model. For each pass, several sample points are extracted with a uniform length interval from the intersection points generated by the basic slicing method. The path pass is then described by a fourth-order polynomial curve. It fits the boundary points and sample points for the
$z$
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$t$
and
$y$
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$t$
relationships, respectively. Based on the spray gun’s motion direction and spray direction, the orientation of each path point is also defined. The parameters of the path pass are optimized by particle swarm optimization to get the optimal uniformity of the resulting coating thickness. Both of the global uniformity and the local uniformity between two adjacent passes are considered. The strength of the proposed approach is validated by comparing the simulation with the basic and other typical algorithms. The results denote that boundary fitting approach could improve the uniformity of coating thickness. It brings about a better performance for the painted workpiece.
Public health interventions successfully mitigated multiple incursions of SARS-CoV-2 Delta variant in the Australian Capital Territory
Authors: Hall Robyn N , Jones Ashley , Crean Emma , Marriott Victoria , Pingault Nevada , Marmor Alexandra , Sloan-Gardner Timothy , Kennedy Karina , Coleman Kerryn , Johnston Vanessa , Schwessinger Benjamin 
Published: February 2023

AbstractThe COVID-19 pandemic has presented a unique opportunity to understand how real-time pathogen genomics can be used for large-scale outbreak investigations. On 12 August 2021, the Australian Capital Territory (ACT) detected an incursion of the SARS-CoV-2 Delta (B.1.617.2) variant. Prior to this date, SARS-CoV-2 had been eliminated locally since 7 July 2020. Several public health interventions were rapidly implemented in response to the incursion, including a territory-wide lockdown and comprehensive contact tracing. The ACT has not previously used pathogen genomics at a population level in an outbreak response; therefore, this incursion also presented an opportunity to investigate the utility of genomic sequencing to support contact tracing efforts in the ACT. Sequencing of >75% of the 1793 laboratory-confirmed cases during the 3 months following the initial notification identified at least 13 independent incursions with onwards spread in the community. Stratification of cases by genomic cluster revealed that distinct cohorts were affected by the different incursions. Two incursions resulted in most of the community transmission during the study period, with persistent transmission in vulnerable sections of the community. Ultimately, both major incursions were successfully mitigated through public health interventions, including COVID-19 vaccines. The high rates of SARS-CoV-2 sequencing in the ACT and the relatively small population size facilitated detailed investigations of the patterns of virus transmission, revealing insights beyond those gathered from traditional contact tracing alone. Genomic sequencing was critical to disentangling complex transmission chains to target interventions appropriately.
Evaluation of a state-wide intervention on salt intake in primary schoolchildren living in Victoria, Australia
Authors: Grimes Carley A , Bolton Kristy A , Trieu Kathy , Reimers Jenny , Armstrong Sian , Bolam Bruce , Beckford Kelsey , Santos Joseph Alvin , Rosewarne Emalie , Dunford Elizabeth K , Jan Stephen , Webster Jacqui , Neal Bruce , Nowson Caryl , Woodward Mark 
Published: February 2023

AbstractObjective:In 2015, the Victorian Salt Reduction Partnership launched a 4-year multifaceted salt reduction intervention designed to reduce salt intake by 1 g/d in children and adults living in Victoria, Australia. Child-relevant intervention strategies included a consumer awareness campaign targeting parents and food industry engagement seeking to reduce salt levels in processed foods. This study aimed to assess trends in salt intake, dietary sources of salt and discretionary salt use in primary schoolchildren pre- and post-delivery of the intervention.Design:Repeated cross-sectional surveys were completed at baseline (2010–2013) and follow-up (2018–2019). Salt intake was measured via 24-h urinary Na excretion, discretionary salt use behaviours by self-report and sources of salt by 24-h dietary recall. Data were analysed with multivariable-adjusted regression models.Setting:Victoria, Australia.Participants:Children aged 4–12 yearsResults:Complete 24-h urine samples were collected from 666 children at baseline and 161 at follow-up. Mean salt intake remained unchanged from baseline (6·0; se 0·1 g/d) to follow-up (6·1; 0·4 g/d) (P = 0·36), and there were no clear differences in the food sources of salt and at both time points approximately 70 % of children exceeded Na intake recommendations. At follow-up, 14 % more parents (P = 0·001) reported adding salt during cooking, but child use of table salt and inclusion of a saltshaker on the table remained unchanged.Conclusion:These findings show no beneficial effect of the Victorian Salt Reduction Partnership intervention on children’s salt intake. More intensive, sustained and coordinated efforts between state and federal stakeholders are required.
Audiovisual Warfare: Music and International Persuasion in Documentary Films during the Spanish Civil War
Authors: LÓPEZ GÓMEZ LIDIA 
Published: February 2023

AbstractDuring the Spanish Civil War, cinema became one of the most powerful weapons of propaganda. The music of the films, full of anthems and political references, was an essential tool for displaying the documentary's intentions and for influencing spectators’ reactions. Between 1936 and 1939, there was a surge in the production of documentaries targeting international audiences, as they were an invaluable resource for engaging the European countries that had signed the Non-Intervention Agreement against involvement in the Spanish conflict. The objective of this article is to analyse the music of the documentaries set in Spain that were exhibited internationally during the years of the war. We will study the politically tendentious uses of anthems and popular songs on the soundtracks, as well as the importance of the figure of the composer – for those documentaries with original music – attending to the social and political circumstances surrounding their participation in the production.
Three distinct symptom profiles among older adults with severe dementia: A latent class analysis
Authors: Malhotra Chetna , Chaudhry Isha , Shafiq Mahham , Malhotra Rahul 
Published: February 2023

AbstractObjectivesOlder adults with severe dementia experience multiple symptoms at the end of life. This study aimed to delineate distinct symptom profiles of older adults with severe dementia and to assess their association with older adults’ and caregiver characteristics and 1-year mortality among older adults.MethodsWe used baseline data from a cohort of 215 primary informal caregivers of older adults with severe dementia in Singapore. We identified 10 indicators representing physical, emotional, and functional symptoms, and responsive behaviors, and conducted latent class analysis. We assessed the association between delineated older adults’ symptom profiles and their use of potentially burdensome health-care interventions in the past 4 months; older adults’ 1-year mortality; and caregiver outcomes.ResultsWe delineated 3 profiles of older adults – primarily responsive behaviors (Class 1; 33%); physical and emotional symptoms with responsive behaviors (Class 2; 20%); and high functional deficits with loss of speech and eye contact (Class 3; 47%). Classes 2 and 3 older adults were more likely to have received a potentially burdensome intervention for symptoms in the past 4 months and have a greater hazard for 1-year mortality. Compared to Class 1, caregivers of Class 2 older adults were more likely to experience adverse caregiver outcomes, that is, higher distress, impact on schedule and health, anticipatory grief, and coping and lower satisfaction with care received (p<0.01 for all).Significance of resultsThe 3 delineated profiles of older adults can be used to plan or optimize care plans to effectively manage symptoms of older adults and improve their caregivers’ outcomes.
The role of social deprivation and depression in dementia risk: findings from the longitudinal survey of health, ageing and retirement in Europe
Authors: Hofbauer L. M. , Rodriguez F. S. 
Published: February 2023

Abstract

Aims
Knowledge on the link of individual social deprivation with dementia is incomplete. We thus aimed to see whether an association with dementia risk can be observed using a recently developed Social Deprivation Index (SoDep Index). Further, as deprivation is related to depression, we investigated the role of depression in the association.

Methods
We analysed data of 11 623 Survey of Health, Ageing and Retirement in Europe (SHARE) respondents. Social deprivation status was determined by SoDep Index score. Dementia was determined by self-reported diagnosis. Dementia risk by social deprivation status was estimated using Cox proportional hazard models, including relevant covariates (gender, marriage status, chronic conditions). Depressive symptom status was added in a second step. Further, we completed subgroup analyses by social deprivation status and analysed the relevance of depressive symptoms in dementia risk in each deprivation group. In an additional sensitivity analyses we corrected for mortality and used impaired cognitive testing performance as an alternative outcome.

Results
High (v. low) social deprivation status was associated with an increased dementia risk (hazard ratio (HR) = 1.79 [95% CI 1.31–2.45]) in the Cox analysis adjusted for covariates only. Further adjustment for depressive symptom status indicated a largely direct association between social deprivation status and dementia risk. Moreover, compared to not having experienced depressive symptoms in the past or at baseline, those with past (HR = 1.67 [95% CI 1.23–2.25]), baseline (HR = 1.48 [95% CI 1.04–2.10]) or stable depressive symptoms (HR = 2.96 [95% CI 2.12–4.14]) had an increased dementia risk. The association between stable depressive symptom status and dementia risk was in the high social deprivation subgroup particularly pronounced. Sensitivity analyses replicated results.

Conclusions
Results add to a growing body of evidence indicating that a public health approach to dementia prevention must address socioeconomic inequity. Results suggest a largely direct association between social deprivation and dementia risk. Adults who experience high social deprivation appear particularly affected by detrimental effects of depressive symptomatology on dementia risk and need intervention.
Multi-Seed Zea Pellets (MSZP) for increasing agroecosystem biodiversity
Authors: Westbrook Anna S. , Amirkhani Masoume , Taylor Alan G. , Loos Michael T. , Losey John E. , DiTommaso Antonio 
Published: February 2023

AbstractIntensive agricultural crop production is typically associated with low biodiversity. Low biodiversity is associated with a deficit of ecosystem services, which may limit crop yield (e.g., low pollination of insect-pollinated crops) at the individual field level or exacerbate the landscape-level impacts of intensive agriculture. To increase biodiversity and enhance ecosystem services with minimal loss of crop production area, farmers can plant desirable non-crop species near crop fields. Adoption of this practice is limited by inefficiencies in existing establishment methods. We have developed a novel seed-molding method allowing non-crop species to be planted with a conventional corn (Zea mays L.) planter, reducing labor and capital costs associated with native species establishment. Common milkweed (Asclepias syriaca L.) was selected as a model native species, because Asclepias plants are the sole food source for monarch butterfly (Danaus plexippus L.) larvae. Stratified A. syriaca seeds were added to a mixture of binder (maltodextrin) and filler (diatomaceous earth and wood flour) materials in a 3D-printed mold with the dimensions of a corn seed. The resulting Multi-Seed Zea Pellets (MSZP), shaped like corn seeds, were tested against non-pelleted A. syriaca seeds in several indoor and outdoor pot experiments. Molding into MSZP did not affect percent emergence or time to emergence from a 2-cm planting depth. Intraspecific competition among seedlings that emerged from an MSZP did not differ from competition among seedlings that emerged from a cluster of non-pelleted seeds. These findings demonstrate the potential of MSZP technology as a precise and efficient method for increasing agroecosystem biodiversity.
Equatorial Undercurrent Influence on Surface Seawater δ18O Values in the Galápagos
Authors: Conroy Jessica L. , Murray Nicole K. , Patterson Gillian S. , Schore Aiden I. G. , Ikuru Ima , Cole Julia E. , Chillagana David , Echeverria Fernando 
Published: February 2023

AbstractStable isotopes of oxygen (δ18O) in seawater reflect the combined influences of ocean circulation and atmospheric moisture balance. However, it is difficult to disentangle disparate ocean and atmosphere influences on modern seawater δ18O values, partly because continuous time series of seawater δ18O are rare. Here we present a nearly nine‐year, continuous record of seawater δ18O values from the Galápagos. Seawater δ18O values faithfully track sea surface salinity and salinity along the equator at 50 m depth. Zonal current velocity within the Equatorial Undercurrent (EUC), directly west of the Galápagos, is strongly correlated with Galápagos surface seawater δ18O values with a 1‐month lag. Reconstructions of Galápagos seawater δ18O values could thus provide a window into past variations in the strength of the EUC, an important influence on large‐scale tropical Pacific climate.
Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer’s disease patients are associated with cognitive impairment
Authors: Xicota Laura , Lagarde Julien , Eysert Fanny , Grenier-Boley Benjamin , Rivals Isabelle , Botté Alexandra , Forlani Sylvie , Landron Sophie , Gautier Clément , Gabriel Cecilia , Bottlaender Michel , Lambert Jean-Charles , Chami Mounia , Sarazin Marie , Potier Marie-Claude 
Published: February 2023

AbstractMorphological alterations of the endosomal compartment have been widely described in post-mortem brains from Alzheimer’s disease (AD) patients and subjects with Down syndrome (DS) who are at high risk for AD. Immunostaining with antibodies against endosomal markers such as Early Endosome Antigen 1 (EEA1) revealed increased size of EEA1-positive puncta. In DS, peripheral cells such as peripheral blood mononuclear cells (PBMCs) and fibroblasts, share similar phenotype even in the absence of AD. We previously found that PBMCs from AD patients have larger EEA1-positive puncta, correlating with brain amyloid load. Here we analysed the endosomal compartment of fibroblasts from a very well characterised cohort of AD patients (IMABio3) who underwent thorough clinical, imaging and biomarkers assessments. Twenty-one subjects were included (7 AD with mild cognitive impairment (AD-MCI), 7 AD with dementia (AD-D) and 7 controls) who had amyloid-PET at baseline (PiB) and neuropsychological tests at baseline and close to skin biopsy. Fibroblasts isolated from skin biopsies were immunostained with anti-EEA1 antibody and imaged using a spinning disk microscope. Endosomal compartment ultrastructure was also analysed by electron microscopy. All fibroblast lines were genotyped and their AD risk factors identified. Our results show a trend to an increased EEA1-positive puncta volume in fibroblasts from AD-D as compared to controls (p.adj = 0.12) and reveal enhanced endosome area in fibroblasts from AD-MCI and AD-AD versus controls. Larger puncta size correlated with PiB retention in different brain areas and with worse cognitive scores at the time of biopsy as well as faster decline from baseline to the time of biopsy. Finally, we identified three genetic risk factors for AD (ABCA1, COX7C and MYO15A) that were associated with larger EEA1 puncta volume. In conclusion, the endosomal compartment in fibroblasts could be used as cellular peripheral biomarker for both amyloid deposition and cognitive decline in AD patients.
Adaptive photoperiod interpretation modulates phenological timing in Atlantic salmon
Authors: Oldham Tina , Oppedal Frode , Fjelldal Per Gunnar , Hansen Tom Johnny 
Published: February 2023

AbstractPhotoperiod, the portion of 24-h cycle during which an organism is exposed to illumination, is an important phenological cue in many animals. However, despite its influence on critical biological processes, there remain many unknowns regarding how variations in light intensity translate into perceived photoperiod. This experiment examined how light intensity variations affect perceived photoperiod in Atlantic salmon (Salmo salar) to determine whether photoperiod interpretation is, a) fixed such that anything above a minimum detection threshold is regarded as ‘illumination’, or b) adaptive and varies with recent light exposure. To do this we compared the frequency of smoltification and sexual maturation between groups of male parr which were exposed to one of eight light regimes on a 12:12 cycling regime (12-hour day/12-hour night). The eight regimes were divided into two treatments, four with ‘High’ daytime light intensity and four with ‘Low’ daytime light intensity. The ‘High' and ‘Low' intensity treatments were each sub-divided into four groups for which the subjective ‘night’ light intensity was 100%, 10%, 1% and 0% of the daytime light intensity, with four replicate tanks of each treatment. The results show that above a minimum detection threshold, Atlantic salmon have adaptive photoperiod interpretation which varies with recent light exposure, and that adaptive photoperiod interpretation modulates the timing of the parr-smolt transformation and sexual maturation. Further, we show that photoperiod interpretation varies between closely related families. Given the influence of phenological timing on species survival, our results reveal a critical role for integration of photoperiod interpretation in attempts to understand how geographically shifting thermal niches due to climate change will affect future populations.
Machine learning determination of motivators of terminal extubation during the transition to end-of-life care in intensive care unit
Authors: Waldauf Petr , Scales Nathan , Shahin Jason , Schmidt Matous , van Beinum Amanda , Hornby Laura , Shemie Sam D. , Hogue Melania , Wind Tineke J. , van Mook Walther , Dhanani Sonny , Duska Frantisek 
Published: February 2023

AbstractProcedural aspects of compassionate care such as the terminal extubation are understudied. We used machine learning methods to determine factors associated with the decision to extubate the critically ill patient at the end of life, and whether the terminal extubation shortens the dying process. We performed a secondary data analysis of a large, prospective, multicentre, cohort study, death prediction and physiology after removal of therapy (DePPaRT), which collected baseline data as well as ECG, pulse oximeter and arterial waveforms from WLST until 30 min after death. We analysed a priori defined factors associated with the decision to perform terminal extubation in WLST using the random forest method and logistic regression. Cox regression was used to analyse the effect of terminal extubation on time from WLST to death. A total of 616 patients were included into the analysis, out of which 396 (64.3%) were terminally extubated. The study centre, low or no vasopressor support, and good respiratory function were factors significantly associated with the decision to extubate. Unadjusted time to death did not differ between patients with and without extubation (median survival time extubated vs. not extubated: 60 [95% CI: 46; 76] vs. 58 [95% CI: 45; 75] min). In contrast, after adjustment for confounders, time to death of extubated patients was significantly shorter (49 [95% CI: 40; 62] vs. 85 [95% CI: 61; 115] min). The decision to terminally extubate is associated with specific centres and less respiratory and/or vasopressor support. In this context, terminal extubation was associated with a shorter time to death.