bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aneurysmal Subarachnoid Haemorrhage and Sex Difference: Analysis of Epidemiology, Outcomes and Risk Factors
Authors: Peng Chao , Zhao Yan , Li Fan , Guo Tie-zhu , Wang Xiang-dong , Wang Bang-yue , Li Jian , Zhang Heng-rui , Yang Yi-fan , Liu Qing-guo , Ren Xin-liang , yang xinyu 
Published: September 2023

Abstract
Background and Purpose
The differences in outcomes after aneurysmal subarachnoid haemorrhage (aSAH) between the different sexes remains controversial. This study aimed to study the differences in epidemiology, outcomes and risk factors between male and female aSAH patients.
Methods
We performed a multicentre retrospective study of aSAH patients from 2017 to 2020. We investigated epidemiology differences between the two sexes. Propensity score matching (PSM) was used to compare short-term outcomes in different sexes. Binary logarithmic regression was performed to investigate the odds ratio for dependent survival in different sexes.
Results
A total of 5407 consecutive aSAH patients were included in this study, and the female-to-male ratio was 1.8:1. The peak incidence of aSAH occurred in the 6th and 7th decade in males and females, respectively. Female patients had more ICA/PCoA aneurysms (53.2%), and male patients had more ACA/ACoA aneurysms (43.2%). The incidence of multiple aneurysms was higher in female patients (21.5% vs. 14.2%, P<0.001). There was no significant difference in outcomes before and after PSM at discharge. The dependent survival risk was only related to the clinical condition upon admission in females. In addition, age of more than 50 years (OR, 1.88; 95% CI, 1.17-3.02; P=0.01) and hypertension (OR, 1.81; 95% CI, 1.25-2.61; P=0.002) were also risk factors in male patients.
Conclusions
The number of female patients was higher than that of male patients. Most aneurysm locations were different between the two groups. There was no significant difference in discharge outcomes before and after PSM. The risk factors for dependent survival were different in female and male patients.
The ChickenGTEx atlas: the genetic regulation of multi-tissue and single-cell transcriptome signatures in chickens
Authors: Fang Lingzhao , Guan Dailu , Bai Zhonghao , Zhu Xiaoning , Zhong Conghao , Hou Yali , Li Houcheng , Lan Fangren , Diao Shuqi , Yao Yuelin , Zhao Bingru , Zhu Di , Li Xiaochang , Pan Zhangyuan , Gao Yahui , Wang Yuzhe , Zou Dong , Wang Ruizhen , Xu Tianyi , Sun Congjiao , Yin Hongwei , Teng Jinyan , Xu Zhiting , Lin Qing , Shi Shourong , Shao Dan , Degalez Fabien , Lagarrigue Sandrine , Wang Ying , Wang Ming-Shan , Peng Minsheng , Rocha Dominique , Charles Mathieu , Smith Jacqueline , Watson Kellie , Buitenhuis Albert , Sahana Goutam , Lund Mogens , Warren Wesley , Frantz Laurent , Larson Greger , Lamont Susan , Si Wei , Zhao Xin , Li Bingjie , Zhang Haihan , Luo Chenglong , Shu Dingming , Qu Hao , Luo Wei , Li Zhenhui , Nie Qing-Hua , Zhang Xiquan , Xiang Ruidong , Liu Shuli , Zhang Zhe , Zhang Zhang , Liu George , Cheng Hans , Yang Ning , Hu Xiaoxiang , Zhou Huaijun 
Published: September 2023

Abstract

Chicken is a valuable model for understanding fundamental biology and vertebrate evolution, as well as a major source of nutrient-dense and lean-protein-enriched food globally. Although it is the first non-mammalian amniote genome to be sequenced, the chicken genome still lacks a systematic characterization of functional variation. Here, through integrating bulk RNA-Seq of 7,015 samples, single-cell RNA-Seq of 127,598 cells and 2,869 whole-genome sequences, we presented an atlas of regulatory variants across 28 chicken tissues and 43 cell types, including millions of regulatory effects on primary expression (protein-coding genes, lncRNA and exon) and post-transcriptional modifications (alternative splicing and 3’ untranslated region alternative polyadenylation). We highlighted distinct molecular mechanisms underlying these regulatory variants and their context dependence and utility in interpreting genome-wide associations of 108 chicken complex traits. Finally, we illustrated lineage-specific features of gene regulation between chickens and mammals, and demonstrated how this resource can assist with cross-species gene mapping of complex traits.
Adaptive Learning Gain based Resilient Control of Multiagent Systems with Partial Uncertain Control Coefficients Under FDI Attacks
Authors: Yang Xiaowu , Long Fei , Lei Bangjun 
Published: September 2023

Abstract
This paper presents a novel approach to security resilient control in collective multiagent systems, incorporating an adaptive learning gain mechanism. The proposed method addresses challenges posed by bounded external disturbances, partial false-data-injection (FDI) attacks on the actuators, and partial unknown time-varying control coefficients. The presented synthesized control consists of following parts. Specifically, a robust adaptive control law with implicit learning is proposed to address the modeling parameterized uncertainties and disturbances. An adaptive learning gain-based control technique is designed to reduce the adversarial effect caused by mismatched disturbances with time-varying parameters, which curbs the cooperative errors to the assigned field. A resilient control approach is established to mitigate the detrimental impact of malicious attacks on actuators. An adaptive control strategy, utilizing a novel congelation of variables, is implemented to address the control issue pertaining to partially unknown control coefficients. This technique ensures that control inputs align with the practical actuators by establishing feasible control bounds. The property of the resulting closed-loop error multiagent systems is analyzed. Finally, the efficacy of the designed controller is illustrated by providing an illustrative example.
Chiral Kirigami for Bend-Tolerant Real-Time Reconfigurable Holograms
Authors: Choi Won Jin , Lee Sang Hyun , Cha Minjeong , Kotov Nicholas 
Published: September 2023

Abstract
Despite the commonality of static holograms, the holography with multiple information layers and reconfigurable grey-scale images at communication frequencies remain a confluence of scientific challenges1-4. One well-known difficulty is the simultaneous modulation of phase and amplitude of electromagnetic wavefronts with a high modulation depth5,6. A less appreciated challenge is scrambling of the information and images with hologram bending7,8. Here, we show that chirality-guided pixelation of plasmonic kirigami sheets enables tunable multiplexed holography at terahertz frequencies needed for 6G communications. The convex and concave structures with slanted Au strips exhibit gradual variations in local chirality facilitating modulation of light ellipticity reaching 40 deg. Real-time switching between three-dimensional images of the letter “M” and the Mona Lisa demonstrate the possibility of complex grey-scale information content. Unexpectedly, the microscale chirality of each pixel experiences little change with bending while retaining controllable reconfigurability upon stretching. The remarkable resilience of chiral holograms to bending and the simplicity of their design with local chirality measures open the door to information technologies with fault-tolerant THz encryption and wearable holographic devices.
Can a New National System Policy for Science and Technology Promote Industrial Restructuring in China's National Innovation Center Cities?
Authors: Song Zhendong , Xu Geni , Jiao Bing , Qu Chen 
Published: September 2023

Abstract
We establish two types of difference-in-difference(DID) models to study the effects of the policy shocks of the new national system of science and technology on the rationalization and advancedization of industrial structure of national innovation center(NIC) cities. Meanwhile, considering the differences in resource endowment between NIC cities and general cities, we use propensity matching analysis(PSM) to establish matching data on the basis of benchmark data to empirically demonstrate the effect of this policy shock on the industrial structure of NIC cities. The study shows that the policy shock has a promoting effect on the level of industrial structure rationalization in the NIC cities, but not significant effect on the industrial structure advancedization, the improvement of the financing environment can promote the development of industrial structure advancement, the growth of personal wealth has a promoting effect on the industrial structure rationalization, and the increase of the government investment is not conducive to the advancement of industrial structure although it can promote the rationalization of the industrial structure in China's NIC cities. Compared with the eastern NIC cities, this policy shock has a greater effect on the rationalization of industrial structure in the Central-western NIC cities of China. In addition, the financing environment and per capita income of NIC cities have a moderating effect on the rationalization of industrial structure under the policy shock. Therefore, NIC cities should actively promote the promotion effect of this policy on the rationalization of industrial structure.
Multi-Task Unsupervised Question Retrieval Method with Enhanced Keyword Features
Authors: Aiguo SHANG , Xinjuan ZHU 
Published: September 2023

Abstract
Currently, a large number of question retrieval solutions rely on supervised methods, which require expensive manual annotations. However, existing unsupervised question retrieval methods lack the reinforcement of keyword features in question representations. To address this issue, this paper proposes an unsupervised question retrieval method called QRTM (Question Retrieval based on Topic Filtering and Multi-Task Learning). Firstly, a topic filtering algorithm called GF is designed, which calculates the distribution of topics and keywords using topic models. It sequentially extracts the topic keywords from the questions to construct unsupervised learning corpus data. Secondly, a multi-task learning approach is adopted to build the question retrieval model. Three tasks are designed in this paper: a short question contrastive learning task; a question generation task with corresponding sequential topic keywords; and the SDN (Similarity Distribution Network) task, which combines autoencoders and attention mechanisms to measure the similarity between questions and sequential topic keywords. These three tasks are trained in parallel to obtain enhanced embeddings of topic keywords in question representations, capturing accurate semantic information of the questions. Comparative and ablation experiments on publicly available question datasets validate that the proposed QRTM method outperforms baseline methods. When using the BERT pre-trained model, the P@1, MAP, and MRR metrics are respectively improved by 8.5%, 5.4%, and 5.0% compared to the baseline model. When using the Roberta model, the corresponding metrics are improved by 4.8%, 4.3%, and 4.4%. QRTM can be applied to transfer learning with pre-trained models such as BERT and RoBERTa, effectively enhancing the accuracy of unsupervised similar question retrieval, with the retrieved similar questions appearing at a higher rank.
Incorporation of Compost and Biochar Enhances Yield and Medicinal Compounds in Seeds of Water-stressed Trigonellia foenum-graecum L. Plants Cultivated in Saline Calcareous Soils
Authors: Shaaban Ahmed , Hemida Khaulood , El-Mageed Taia Abd , Semida Wael , AbuQamar Synan , El-Tarabily Khaled , El-Saadony Mohamed , Al-Elwany Omar 
Published: September 2023

Abstract

Background The combination of compost and biochar (CB) plays an important role in soil restoration and mitigation strategies against drought stress in plants. In this study, the impact of CB was determined on the characteristics of saline calcareous soil and medicinal productivity of fenugreek plants (Trigonella foenum-graecumL.). The field trials examined CB rates (CB0,CB10and CB20corresponding to 0, 10, and 20 t ha‒1, respectively) under deficit irrigation (DI0%, DI20%and DI40%receiving 100, 80 and 60% ETc, respectively) conditions on growth, seed yield (SY), quality, and water productivity (WP) of fenugreek grown in saline calcareous. Results In general, DI negatively affected the morpho-physio-biochemical responses in plants cultivated in saline calcareous soils. However, amendments of CB10or CB20improved soil structure under DI conditions. This was evidenced by the decreased pH, ECe and bulk density but increased organic matter, macronutrient (N, P and K) availability, water retention, and total porosity; thus, maintaining better water and nutritional status. These soil modifications improved chlorophyll, tissue water contents, cell membrane stability, leaf PSII efficiency, and nutritional homeostasis in leaves of drought-stressed plants. This was also supported by increased osmolytes, non-enzymatic, and enzymatic activities under DI conditions. Regardless of DI regimes, SY was significantly improved by 40.0 and 102.5%, seed alkaloids by 87.0 and 39.1%, trigonelline content by 43.8 and 16.7% and WP by 40.9 and 104.5% in plants treated with CB10and CB20, respectively. Conclusions Overall, application of organic amendments of CB can be a promising sustainable solution for improving saline calcareous soil properties, mitigating negative effects of DI stress, and enhancing crop productivity in arid and semi-arid agro-climates.
Development of a practical engineering tool for axially loaded piles calculation
Authors: Doghman Mirna , Mroueh Hussein , Burlon Sébastien 
Published: September 2023

Abstract

The assessment of the head load-displacement response of a pile under axial loading is the key aspect for analysing the pile behaviour under such type of loading. Therefore, an adequate modelling of the soil-pile interface makes it possible for numerical investigations to give a relevant prediction of the pile response. The commonly used approaches for displacement analysis either consider that the soil resistance can be simulated by a series of discrete springs, or that the soil is a continuum. However, the use of either approaches presents some drawbacks related to the disregard of the rheological aspect of the problem, or to the need of time-consuming numerical techniques. This paper presents a practical 1D approach, based on the finite element method, for soil-pile interface modelling. This approach is coupled with a simplified flow rule, used to simulate the interface response, based on the analogy between the behaviour of the soil-pile interface and the interface of a direct shear test. The response of a theoretical pile using the developed approach is compared to results of a load-transfer analysis and results of a 3D analysis using the commercial finite difference software (FLAC3D). The results allow to estimate the change in pile shaft resistance induced by normal stress variations along the pile.
Relationship between paravertebral muscle degeneration and spinal -pelvic sagittal parameters in patients with lumbar disc herniation
Authors: BAO TIANLIAN , ZHAO KEYU , WANG CHUNMEI , YANG WUPENG , WANG YONGJIANG , WANG TIANTIAN , ZHANG QINGXIN , GAO FENG , LIU HAO , TAO XIAOYANG , GAO GANG , ZHANG TINXIN 
Published: September 2023

Abstract
Lumbar disc herniation (LDH) is a clinically common degenerative disease of the spine, and spinal–pelvic sagittal balance and paravertebral muscle degeneration have been a research focus in recent years. To explore the relationship between the degeneration of paravertebral muscle and the changes in the spinal–pelvic sagittal parameters in LDH patients, 105 LDH patients (experimental group) and 63 healthy volunteers (control group) hospitalized in Ordos Central Hospital from January 2020 and January 2023 were included as study subjects. All the patients underwent lumbar magnetic resonance imaging and spinal X-ray using uniform criteria. The correlation between the paravertebral muscle and sagittal–pelvic sagittal parameters of the patients with LDH was obtained from two imaging examinations, and the data were organized and grouped to explore the correlation between these parameters. No significant difference in general data existed between the groups (P > 0.05). In the L4/5 LDH patients group, the ratio of fat infiltration (FIR) in the healthy side (multifidus (MF) and erector spinae (ES)) was negatively correlated with the lumbar lordosis (LL)(r = -0.461, r = -0.486, P < 0.05). The relative cross-sectional area (RCSA) of the bilateral MF was positively correlated with the pelvic tilt (r = 0.549, r = 0.515, P < 0.05). The bilateral ES RCSA was negatively correlated with the sagittal vertical axis (r = -0.579, r = -0.621, P < 0.05). A positive correlation existed between the RCSA and thoracic kyphosis in the healthy side ES (r = 0.614, P < 0.05). In the L5/S1 LDH patients group, a negative correlation existed between the FIR and LL in the healthy side ES (r = -0.579, P < 0.05). Thus, the paravertebral muscle parameters were correlated with the spinal–pelvic sagittal parameters in the patients with LDH.
Ecological Correlates and Predictors of Lassa Fever Incidence in Ondo State, Nigeria 2017 - 2021: An Emerging Urban Trend
Authors: Cadmus Simeon , Taiwo Olalekan , Akinseye Victor , Cadmus Eniola , Famokun Gboyega , Fagbemi Stephen , Ansumana Rashid , Omoluabi Anddy , Ayinmode Adekunle , Oluwayelu Daniel , Odemuyiwa Solomon , Tomori Oyewale 
Published: September 2023

Abstract

Lassa fever (LF) is a highly prevalent disease in many West African countries, including Nigeria. Efforts to combat the disease have primarily focused on rural areas where interactions between rodents and humans are common. However, recent studies indicate a shift in the occurrence of LF from rural to urban areas. We analysed secondary data of reported LF outbreaks from 2017 to 2021 in Ondo State, Nigeria, to identify the distribution pattern, ecological variations, and other determinants of disease spread from the ward level. Data utilised include LF incidence, ecological variables involving elevation, population, nighttime light intensity, vegetation, temperature, market presence, road length, and building area coverage. ArcGIS Pro 3.0 software was employed for spatial analysis. Results revealed a spatio-temporal clustering of LF incidents between 2017 and 2021, with an increasing trend followed by a decline in 2021. All wards in Owo Local Government Area were identified as hotspots for LF. The ecological variables exhibited significant correlations with the number of LF cases in the wards, except for maximum temperature. Notably, these variables varied significantly between wards with confirmed LF and those without. Therefore, it is important to prioritise strategies for mitigating LF outbreaks in urban areas of Nigeria and other West African countries.
Compliance with follow-up in patients with testicular cancer receiving adjuvant chemotherapy: A novel study
Authors: Erkan Anil , Keten Tanju , Guzel Ozer , Barali Deniz , Basboga Serdar , Kilic Metin , Caglayan Volkan , Koc Akif , Tuncel Altug 
Published: September 2023

Abstract
Purpose
The aim of this study was to investigate the compliance with follow-up in patients receiving adjuvant chemotherapy (ACT) for testicular cancer at two academic hospitals.
Methods.
The study analyzed 104 patients with testicular tumors who had undergone surgery at least a year before and received ACT between March 2017 to March 2022. The mean follow-up was 29.2 ± 16.2 (12–73) months. Patients were classified as fully compliant (100% compliance), moderately compliant (50–99%), poorly compliant (1–49%), and non-compliant (no attendance) according to their compliance with the follow-up schedule.
Results
At the end of the first year, 76% of patients were fully compliant. By the end of the second year, this number dropped to 50%. Furthermore, 25% of patients were identified as non-compliant in the second year, and only 4.3% in the third year. When comparing patients who were compliant and non-compliant at first and second-year follow-up, no statistically significant difference was found according to age, tumor size, disease stage, or ACT regimen (p = 0.938, p = 0.784, p = 0.867, and p = 0.282, respectively).
Conclusion and Implications for Cancer Survivors
This study showed that full compliance with follow-up gradually decreased over the years and that the factors examined were not able to predict this decrease. Prospective studies can help to design individualized education and follow-up programs, taking into account the tumor stage of each patient.
Antimicrobial and antibiofilm activity of pyrazolone based Sm(III) and Dy(III) metal chelates against Staphylococcus aureus and Candida albicans
Authors: Philip Surya , Mohanan Kochukittan 
Published: September 2023

Abstract
Staphylococcus aureus and Candida albicans are most common bacterial and fungal agents responsible for blood stream infections. The studies have shown that about 20% of all Candida albicans infections occur with Staphylococcus aureus and are polymicrobial in nature. These species can lead to hospital-acquired infections as they have the ability to form persistent biofilms in medical devices. Development of novel therapeutic agents are required to target these polymicrobial infections. The present work focuses on synthesis, characterization, antimicrobial and antibiofilm activity of pyrazolone based lanthanide metal chelates. The Sm(III) and Dy(III) complexes showed promising antimicrobial and antibiofilm activity towards Staphylococcus aureus and Candida albicans respectively.
Role of hypermethylated SLC5A8 in follicular thyroid cancer diagnosis and prognosis prediction
Authors: Yang Yan , Liao Chenjin , Yang Qian , Li Yuxia , Tang Yunxiang , Xu Bin 
Published: September 2023

Abstract

OBJECTIVE Thyroid cancer is one of the most frequently reported endocrine system malignancies. It is difficult to distinguish follicular thyroid cancer (FTC) from follicular thyroid adenoma (FTA) during pathological diagnosis in patients without lymph nodes or distant metastases. Therefore, we conducted a retrospective study to investigate the significance of SLC5A8 methylation and expression in the diagnosis and prognosis of FTC. METHODS We used 165 tissue samples, including FTC (n = 58), thyroid tumors of uncertain malignant potential (TT-UMP, n = 40), and FTA (n = 67), to explore the differences in SLC5A8 methylation and mRNA transcription in different pathological types. Survival analysis was conducted to evaluate the recurrence rate at a five-year follow-up. RESULTS The SLC5A8 methylation positive rate was higher in patients with thyroglobulin ≥ 40 µg/l and Chol ≥ 5.17 mmol/l, and it was higher in patients with FTC (n = 42, 72.4%) than those with FTA (n = 27, 40.3%) and TT-UMP (n = 23, 57.5%). The relative concentration of SLC5A8 mRNA was lower in patients with FTC than in those with FTA (p < 0.05). At five-year follow-ups, patients that were SLC5A8 methylation-positive had a higher recurrence rate than those who were methylation-negative. CONCLUSIONS Our current study indicates that SLC5A8 gene methylation occurs more commonly in patients with FTC than in those with FTA. The differences in SLC5A8 methylation and expression among FTA, FTC, and TT-UMP provide an important basis for further exploration of epigenetic changes in the occurrence, development, and prognosis of thyroid cancer. Our findings need to be further validated in larger populations with long-term follow-up in the future.