bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of the sodium fluorescein and YELLOW 560 nm filter for the resection of pediatric posterior fossa lesions
Authors: Ott Christian , Proescholdt Martin , Friedrich Monika , Hoehne Julius , Rosengarth Katharina , Schmidt Nils-Ole , Schebesch Karl-Michael 
Published: December 2022

Abstract
Purpose
This study aimed to verify the feasibility, safety, and benefit of using fluorescein sodium (FL) and a YELLOW 560 nm filter in posterior fossa tumors in children.

Methods
All cases of pediatric posterior fossa tumors that have undergone surgery using fluorescein (2018–2022) have been included and were examined retrospectively. In those cases where resection of the tumor was planned, a blinded neuroradiologist distinguished gross total resection and subtotal resection according to the postoperative MRI findings. The surgical report and medical files were reviewed regarding the intraoperative staining grade and adverse events. The grade of fluorescent staining of the targeted lesion was assessed as described in the surgical reports. The screening was conducted for any reference to the degree of fluorescent staining: “intense,” “medium,” “slight,” and “no staining.”

Results
19 cases have been included. In 14 cases, a complete resection was initially intended. In 11 of these cases, a gross total resection could be achieved (78.6%). Staining was described as intense in most cases (58.8%). Except for yellow-colored urine, no side effects obviously related to FL were found throughout the observation period.

Conclusion
In combination with a specific filter, FL is a reliable, safe, and feasible tool in posterior fossa surgery in children.
Individual differences in resilience to stress are associated with affective flexibility
Authors: Rademacher Lena , Kraft Dominik , Eckart Cindy , Fiebach Christian J. 
Published: December 2022

AbstractCognitive flexibility is frequently linked to resilience because of its important contribution to stress regulation. In this context, particularly affective flexibility, defined as the ability to flexibly attend and disengage from affective information, may play a significant role. In the present study, the relationship of cognitive and affective flexibility and resilience was examined in 100 healthy participants. Resilience was measured with three self-report questionnaires, two defining resilience as a personality trait and one focusing on resilience as an outcome in the sense of stress coping abilities. Cognitive and affective flexibility were assessed in two experimental task switching paradigms with non-affective and affective materials and tasks, respectively. The cognitive flexibility paradigm additionally included measures of cognitive stability and spontaneous switching in ambiguous situations. In the affective flexibility paradigm, we explicitly considered the affective valence of the stimuli. Response time switch costs in the affective flexibility paradigm were significantly correlated to all three measures of resilience. The correlation was not specific for particular valences of the stimuli before or during switching. For cognitive (non-affective) flexibility, a significant correlation of response time switch costs was found with only one resilience measure. A regression analysis including both affective and cognitive switch costs as predictors of resilience indicated that only affective, but not cognitive switch costs, explained unique variance components. Furthermore, the experimental measures of cognitive stability and the rate of spontaneous switching in ambiguous situations did not correlate with resilience scores. These findings suggest that specifically the efficiency of flexibly switching between affective and non-affective information is related to resilience.
Psychosocial distress in young adults surviving hematological malignancies: a pilot study
Authors: Wittwer Andreas , Sponholz Kristin , Frietsch Jochen J. , Linke Paul , Kropp Peter , Hochhaus Andreas , Hilgendorf Inken 
Published: December 2022

Abstract
Purpose
Survivors of cancer during young adulthood face multiple psychosocial challenges following treatment. This study explores psychosocial distress and unmet needs among young adult survivors treated of hematological malignancies.

Methods
A total of 85 young adults aged between 18 and 39 years at time of diagnosis, were invited to join the survey after the completion of treatment with curative intent. Sociodemographic data and the need for advice were gathered with a self-report questionnaire. A set of standardized questionnaires for quality of life (EORTC QLQ-C30), psychosocial stressors (PHQ-S), fear of progression (PA-F-KF), cancer-related fatigue (EORTC QLQ-FA12), and symptoms of anxiety (GAD-7) or depression (PHQ-9) was employed. Descriptive statistics and multivariate analysis were conducted.

Results
Forty-seven young adult cancer survivors responded. A quarter of patients (26%) reported depressive symptoms, 15% suffered from anxiety, 36% from fear of progression, and 21% reported increased psychosocial stressors. They had a lower QoL than the general population and reported poorer outcomes on all single-item and multi-symptom scales. Employment was significantly associated with lower levels of psychosocial distress, anxiety, fatigue, and better QoL.

Conclusion
Young adult cancer survivors exhibited a high disposition for psychosocial distress. They reported excessive demands in everyday life and resumption of work. However, a longitudinal study of young adult cancer survivors is needed to confirm the results of this pilot study. In future, psycho-oncological and social support need to become an inherent part of the aftercare of survivors of young adult cancer survivors.
Treatment with head-lift exercise in head and neck cancer patients with dysphagia: results from a randomized, controlled trial with flexible endoscopic evaluation of swallowing (FEES)
Authors: Dotevall Hans , Tuomi Lisa , Petersson Kerstin , Löfhede Helena , Bergquist Henrik , Finizia Caterina 
Published: December 2022

Abstract
Background
This randomized study aimed to evaluate the effects of the Shaker head-lift exercise (HLE) to improve dysphagia following oncologic treatment for head and neck cancer (HNC).

Methods
Patients with dysphagia following oncologic treatment for HNC were randomly assigned to intervention (n = 23) or control (standard dysphagia management, n = 24) groups. Swallowing was evaluated at baseline and at 8-week follow-up using flexible endoscopic evaluation of swallowing (FEES) and self-perceived swallowing with the Eating Assessment Tool (EAT-10). Analysis was performed regarding secretion, initiation of swallow, residue after swallowing, and penetration/aspiration.

Results
Few statistically significant differences were found in the FEES analysis. Some improvement of self-perceived swallowing function was found in both groups. Adherence to training was high.

Conclusions
This randomized study regarding the effect of the HLE demonstrated that swallowing outcome measures used in assessment of FEES did not improve in patients treated with radiotherapy for patients with dysphagia following HNC.
Postural instability-induced compensative movements in virtual reality
Authors: Kállai János , Zsidó András Norbert , Tamás István , Topa Kristóf , Kállai Kata M. , Páll Tamás 
Published: December 2022

AbstractDuring virtual reality usage, two egocentric mental representations are constructed simultaneously. The first representation is rooted in the physical reality in which VR is set up, and the second originates from the mental construction of a computer-generated virtual environment. In both cases, participants configure their posture based on multimodal stimuli while responding to environmental cues. In most cases, the postural cues provided by the digital and real environment may be conflicting. In this study, 50 right-handed volunteers were enrolled. In a pre-test session, attentional focus-related personality bias (perspective-taking) was assessed, and afterward, postural movements and presence experiences were measured while the participants performed a spatial orientation task in VR. Participants were placed in an upright position with their right hands positioned in front of a physically real point on the laboratory wall. Afterward, participants were exposed to a VR environment in which they performed a room-tilting task. Participants with higher hand-related presence scores showed decreased compensatory hand drift in the VR environment. The rate of contralateral hand drift showed a reversed association with the intensity of the perspective-taking trait. VR-induced postural instability can be attenuated by the compensative hand drift that alleviates the conflicts between the two rival inner VR and outer VR environments that compete for attention and provide different reference cues.
High performance of the automated ADVIA Centaur Systems SARS-CoV-2 Antigen Assay in nasopharyngeal samples with high viral load
Authors: Ríos Esther , Medrano Sara , Alvarez Mar , Valderrama María José , Vallejo Luis , Delgado-Iribarren Alberto , Culebras Esther 
Published: December 2022

AbstractADVIA Centaur SARS-CoV-2 Antigen (COV2Ag) Assay (Siemens Healthineers) was evaluated for SARS-CoV-2 detection. A total of 141 nasopharyngeal samples were analyzed by this technique and results were compared with those obtained by quantitative reverse-transcription polymerase chain reaction (RT-PCR). The overall sensitivity and specificity of the test were 68.70% and 70%, respectively. Regarding cycle threshold (Ct) values, the COV2Ag test showed a sensitivity of 93.75% and 100% for nasopharyngeal samples with Ct < 25 and < 20, respectively. ADVIA Centaur COV2Ag Assay is a useful, automated, and rapid technique for early SARS-CoV-2 diagnosis and isolation of the infected individuals, avoiding its transmission.
Comparing magnetic resonance liver fat fraction measurements with histology in fibrosis: the difference between proton density fat fraction and tissue mass fat fraction
Authors: Bawden Stephen James , Hoad Caroline , Kaye Philip , Stephenson Mary , Dolman Grace , James Martin W. , Wilkes Emilie , Austin Andrew , Guha Indra Neil , Francis Susan , Gowland Penny , Aithal Guruprasad P. 
Published: December 2022

Abstract
Objective
Magnetic resonance spectroscopy (MRS) provides a powerful method of measuring fat fraction. However, previous studies have shown that MRS results give lower values compared with visual estimates from biopsies in fibrotic livers. This study investigated these discrepancies and considered whether a tissue water content correction, as assessed by MRI relaxometry, could provide better agreement.

Materials and methods
110 patients were scanned in a 1.5 T Philips scanner and biopsies were obtained. Multiple echo MRS (30 × 30 ×  30 mm volume) was used to determine Proton Density Fat Fraction (PDFF). Biopsies were assessed by visual assessment for fibrosis and steatosis grading. Digital image analysis (DIA) was also used to quantify fat fraction within tissue samples. T1 relaxation times were then used to estimate tissue water content to correct PDFF for confounding factors.

Results
PDFF values across the four visually assessed steatosis grades were significantly less in the higher fibrosis group (F3–F4) compared to the lower fibrosis group (F0–F2). The slope of the linear regression of PDFF vs DIA fat fraction was ~ 1 in the low fibrosis group and 0.77 in the high fibrosis group. Correcting for water content based on T1 increased the gradient but it did not reach unity.

Discussion
In fibrotic livers, PDFF underestimated fat fraction compared to DIA methods. Values were improved by applying a water content correction, but fat fractions were still underestimated.
Cognitive science meets the mark of the cognitive: putting the horse before the cart
Authors: Gough Joe 
Published: December 2022

AbstractAmong those living systems, which are cognizers? Among the behaviours of, and causes of behaviour in, living systems, which are cognitive? Such questions sit at the heart of a sophisticated, ongoing debate, of which the recent papers by Corcoran et al. (2020) and Sims and Kiverstein (2021) serve as excellent examples. I argue that despite their virtues, both papers suffer from flawed conceptions of the point of the debate. This leaves their proposals ill-motivated—good answers to the wrong question. Additionally, their proposals are unfit to serve the legitimate roles for characterizations of cognition.
Support Theorem for Lévy-driven Stochastic Differential Equations
Authors: Kulyk Oleksii 
Published: December 2022

AbstractWe provide a support theorem for the law of the solution to a stochastic differential equation (SDE) with jump noise. This theorem applies to quite general Lévy-driven SDEs and is illustrated by examples with rather degenerate jump noises, where the theorem leads to an informative description of the support.
A paradigm-based explanation of trust
Authors: Bieber Friedemann , Viehoff Juri 
Published: December 2022

AbstractThis article offers a functionalist account of trust. It argues that a particular form of trust—Communicated Interpersonal Trust—is paradigmatic and lays out how trust as a social practice in this form helps to satisfy fundamental practical, deliberative, and relational human needs in mutually reinforcing ways. We then argue that derivative (non-paradigmatic) forms of trust connect to the paradigm by generating a positive dynamic between trustor and trustee that is geared towards the realization of these functions. We call this trust’s proleptic potential. Our functionalist approach does not only provide important insights into the practice of trust and its place in the broader web of social life, but also illuminates existing philosophical debates. First, pointing out how opposing theoretical accounts of trust each capitalise on only one of its functions, our paradigm-based approach reveals why they each contain a kernel of truth but are also deficient: the optimal realization of each function is tied to the existence of the other functions as well. Second, we show how a functionalist re-orientation can illuminate two recent disputes regarding (i) the question whether trust is explanatorily two- or three-place and (ii) whether (and to what extent) we can decide to trust others.
Armut, Hunger, Hilfe
Authors: Schoneville Holger 
Published: December 2022

ZusammenfassungVor dem Hintergrund der aktuellen Steigerungen der Kosten des alltäglichen Lebens, insbesondere auch im Bereich der Ernährung, beschäftigt sich der Beitrag mit Fragen von Armut und Essen im Kontext der Sozialen Arbeit. Dabei wird der Versuch einer Einordnung und Diskussion von Hilfsangeboten im Feld der Sozialen Arbeit vorgenommen, die als Ernährungshilfen verstanden werden können. Der Beitrag zielt auf eine Einordnung des Feldes sowie kritische Diskussion der Armutshilfen und ringt dabei um eine professionspolitische Positionierung.
Peritoneal Surface Malignancies Originating From Urachal Carcinoma: Case Reports and Review of the Literature
Authors: Van Breusegem Paulien , Verswijvel Geert , Fransis Sabine , Van der Speeten Kurt 
Published: December 2022

AbstractUrachal carcinoma (UC) is a rare and aggressive tumor arising from the urachal remnants, with the potential for peritoneal dissemination. Patients diagnosed with UC often have a poor prognosis. To date, there is no standardized treatment. Our objective is to present two cases of patients with peritoneal carcinomatosis (PC) secondary to an UC, who were treated with cytoreductive surgery (CRS) and hyperthermic peroperative intraperitoneal chemotherapy (HIPEC). A review of the literature on CRS and HIPEC in UC suggests CRS and HIPEC to be a safe and viable treatment option. Two patients with PC of UC underwent CRS and HIPEC in our institution. All available data were gathered and reported on. A literary search was carried out to find all available cases of patients with PC secondary to UC treated with CRS and HIPEC. Both patients underwent CRS and HIPEC and are currently free of recurrence. Literature research revealed nine other publications adding up to a total of 68 additional cases. CRS and HIPEC can provide satisfactory long-term oncological outcome with acceptable morbidity and mortality rates in patients with PC of urachal origin. It should be considered as a safe and feasible treatment option with curative potential.
Mechanical Hamiltonian systems with respect to linear Poisson structures and Jacobi–Reeb dynamics
Authors: Iglesias Ponte D. , Marrero J. C. , Padrón E. 
Published: December 2022

AbstractIn this paper, we present a relation between Jacobi–Reeb dynamics and the dynamics associated with a mechanical Hamiltonian system with respect to a linear Poisson structure on a vector bundle. For this purpose, we will use the so-called Jacobi bundle metrics induced by the mechanical Hamiltonian system. These constructions extend classical results on the relation between standard mechanical Hamiltonian systems on cotangent bundles and Reeb dynamics.
New possibilities for engaging school teachers in widening participation: professional development to support student aspirations
Authors: Prieto Elena , Sincock Kristina , Patfield Sally , Fray Leanne , Gore Jennifer 
Published: December 2022

AbstractAccess to higher education remains elusive for many young people despite substantial investment in outreach interventions, most of which target students in underrepresented equity groups. This paper explores an alternative approach to widening participation in Australia that focuses on teacher professional development to support student aspirations. We examine school teachers’ responses to a course designed to develop their conceptual understanding of aspirations and provide a framework for developing aspirations-related initiatives with their students and colleagues. The course pilot was evaluated drawing on surveys (N = 49) and interviews (N = 21). Teachers reported that they gained the following: (1) access to robust evidence of factors affecting aspirations; (2) relevant theoretical perspectives to conceptualise aspirations in new ways; and (3) insights on practical strategies with which they might nurture student pathways to higher education. To support widening participation in higher education, we argue that the scope of current outreach initiatives offered by universities must broaden to capitalise on the untapped potential of teachers.
Experimental investigation and development of a deep learning framework to predict process-induced surface roughness in additively manufactured aluminum alloys
Authors: Muhammad Waqas , Kang Jidong , Ibragimova Olga , Inal Kaan 
Published: December 2022

AbstractA deep learning framework is developed to predict the process-induced surface roughness of AlSi10Mg aluminum alloy fabricated using laser powder bed fusion (LPBF). The framework involves the fabrication of round bar AlSi10Mg specimens, surface topography measurement using 3D laser scanning profilometry, extraction, coupling, and streamlining of roughness and LPBF processing data, feature engineering to select the relevant feature set and the development, validation, and evaluation of a deep neural network model. A mix of core and contour-border scanning strategies are employed to fabricate four sets of specimens with different surface roughness conditions. The effects of different scanning strategies, linear energy density (LED), and specimen location on the build plate on the resulting surface roughness are discussed. The inputs to the deep neural network model are the AM process parameters (i.e., laser power, scanning speed, layer thickness, specimen location on the build plate, and the x,y grid location for surface topography measurements), and the output is the surface profile height measurements. The proposed deep learning framework successfully predicts the surface topography and related surface roughness parameters for all printed specimens. The predicted surface roughness ($${S}_{a}$$

S
a

) measurements are well within 5% of experimental error for the majority of the cases. Moreover, the intensity and location of the surface peaks and valleys as well as their shapes are well predicted, as demonstrated by comparing roughness line scan results with corresponding experimental data. The successful implementation of the current framework encourages further applications of such machine learning-based methods toward AM material development and process optimization.
eImmunonkologie: Development and Launch of a Virtual Education Platform for the Immunotherapy of Cutaneous Neoplasms
Authors: Kaufmann Matthias D. , Steeb Theresa , Wessely Anja , Meyerolbersleben Marion , French Lars E. , Berking Carola , Heppt Markus V. 
Published: December 2022

AbstractThe use of immunotherapies in clinical practice has significantly expanded treatment options and improved the prognosis of patients with advanced cancers over the past decade. We have developed a virtual teaching module entitled “eImmunonkologie” which is the first interdisciplinary virtual course on immuno-oncology for medical students in German-speaking countries.
Pilot-Scale Test of Flue Gas Recirculation for The Silicon Process
Authors: Andersen Vegar , Solheim Ingeborg , Gaertner Heiko , Sægrov-Sorte Bendik , Einarsrud Kristian Etienne , Tranell Gabriella 
Published: December 2022

AbstractFlue gas recirculation (FGR) for the silicon process may facilitate increasing the CO2 concentration in the off-gas, which will be beneficial for potential future carbon capture. Lower oxygen concentration in the combustion gas will also reduce NOX emissions. An existing 400 kVA Submerged Arc Furnace (SAF) pilot setup was modified to be able to recirculate flue gas and equipped with gas analysis to monitor both the flue gas and the mixed combustion gas entering the furnace. Over a running period of 80 h, including 32 h of startup, twelve different combinations of FGR ratios and flow rates were tested using typical industrial raw materials. Increased CO2 flue gas concentrations were successfully demonstrated with concentrations over 20 vol % CO2. Emissions of NOX were shown to be reduced when isolating stable comparable periods within each tapping cycle.
Graphical Abstract
Identifying key sectors in the regional economy: a network analysis approach using input–output data
Authors: DePaolis Fernando , Murphy Phil , De Paolis Kaluza M. Clara 
Published: December 2022

AbstractBy applying network analysis techniques to large input–output system, we identify key sectors in the local/regional economy. We overcome the limitations of traditional measures of centrality by using random-walk based measures, as an extension of Blöchl et al. (Phys Rev E 83(4):046127, 2011). These are more appropriate to analyze very dense networks, i.e. those in which most nodes are connected to all other nodes. These measures also allow for the presence of recursive ties (loops), since these are common in economic systems (depending to the level of aggregation, most firms buy from and sell to other firms in the same industrial sector). The centrality measures we present are well suited for capturing sectoral effects missing from the usual output and employment multipliers. We also develop and make available an R implementation for computing the newly developed measures.