bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Correlation between Leukocytes and Bacterial Number from Urine of Type 2 Diabetes Mellitus Patients Using Urine Analyzer
Authors: Agustina Novia , Pratiwi Diana , Istiqomah Nurul 
Published: July 2023

Diabetes Mellitus (DM) is a chronic metabolic disorder. DM can occur if the pancreas does not produce enough insulin or the insulin that is produced isn’t effectively used. Patients with diabetes mellitus have a high risk for chronic microvascular complications, including infection. This research aimed to determine the correlation between leukocytes and bacterial number from urine of patients with Type 2 Diabetes Mellitus at the X Hospital Blitar. This research used a cross sectional method, with 47 urine samples of Type 2 Diabetes Mellitus patients by purposive sampling, were tested with urine analyzer. The result showed that the number of high leukocytes was 13 (28%) respondents and normal leukocytes was 34 (72%) respondents. While the number of bacteria from respondents was normal 21 (45%) and high number was 26 (55%). Based on the Spearman-rho correlation test on SPSS, it can be concluded that there was a significant relationship between leukocytes with bacterial number of urine from Type 2 Diabetes Mellitus patients, with sig = 0,000 (0,05) and the correlation coefficient = 0,515.
Efek Antelmintik Ekstrak Metanol Kulit Batang Nangka (Artocarpus heterophyllus) terhadap Cacing Ascaris lumbricoides
Authors: Hasan Hamsidar , Ain Thomas Nur , Taupik Muhammad , Potabuga Gita 
Published: July 2023

Jackfruit (Artocarpus heterophyllus) is a type of plant that grows in Indonesia which functions as a food ingredient and as traditional medicine. Generally, this genus contains prenylated flavonoid compounds. This study aimed to determine the anthelmintic effect of jackfruit bark extract against Ascaris lumbricoides worms by utilizing total maceration with methanol solvent as the extraction method, which yielded 6.61%. Roundworm Ascaris lumbricoides are found in pig intestines. The samples were divided into 5 groups, including positive control of 250 mg combantrin solution, negative control of NaCMC and a treatment group of jackfruit bark extract with a concentration of 1%, 3%, and 5%. Each group consisted of three worms, incubated at 37oC for 24 hours with a 6 hours interval. The results showed that at a concentration of 5%, a jackfruit bark extract was efficient as an anthelmintic caused two worms to lyse at 6 hours and one at 12 hours.
Size Dependence of the Bouncing Barrier in Protoplanetary Dust Growth
Authors: Arakawa Sota , Okuzumi Satoshi , Tatsuuma Misako , Tanaka Hidekazu , Kokubo Eiichiro , Nishiura Daisuke , Furuichi Mikito , Nakamoto Taishi 
Published: July 2023

Abstract
Understanding the collisional behavior of dust aggregates is essential in the context of planet formation. It is known that low-velocity collisions of dust aggregates result in bouncing rather than sticking when the filling factor of colliding dust aggregates is higher than a threshold value. However, a large discrepancy between numerical and experimental results on the threshold filling factor was reported so far. In this study, we perform numerical simulations using soft-sphere discrete element methods and demonstrate that the sticking probability decreases with increasing aggregate radius. Our results suggest that the large discrepancy in the threshold filling factor may reflect the difference in the size of dust aggregates in earlier numerical simulations and laboratory experiments.
Illustrated catalogue of sphaeromatoid isopods (Crustacea, Malacostraca) in the Canadian Museum of Nature (CMN)
Authors: Khalaji-Pirbalouty Valiallah , Gagnon Jean-Marc 
Published: July 2023

Zoological collections are major treasures representing the history of animal biodiversity on Earth and are an important resource for biodiversity and conservation research. The Canadian Museum of Nature (CMN) has one of the oldest crustacean collections in North America.
Here, we provide an illustrated catalogue of the superfamily Sphaeromatoidea Latreille, 1825, deposited in the Canadian Museum of Nature’s Crustacea Collection (CMNC). In this paper, we report 18 species, belonging to 3 families and 14 genera. The majority of species belong to the family Sphaeromatidae with 16 species, followed by the Ancinidae and the Tecticipitidae each with one species. We present a bibliography of the original description, current taxonomic status, the type locality, geographic distribution, and an updated illustration for all species.
Note sur l’effet d’une chauffe sur les propriétés électriques de pierres calcaires du Lutétien
Authors: Souffaché Blaise , Tabbagh Alain 
Published: July 2023

Les pierres calcaires du Lutétien ont été largement utilisées aux époques médiévale et moderne pour la construction de monuments dans la partie centrale du bassin de Paris. On présente ici des mesures de leurs propriétés électriques en laboratoire dans la gamme de fréquence [100 Hz – 10 MHz] sur des échantillons extraits des mêmes lits. Les mesures réalisées d’une part à la température ambiante et d’autre part après une chauffe à 600 °C et retour à l’ambiante montrent que la dépendance avec la teneur en eau comme les variations en fréquence sont très peu modifiées. Ceci permet d’affirmer que les propriétés mécaniques seraient conservées après un incendie les ayant portées à cette température et confirme l’intérêt de l’utilisation in situ de la méthode électrostatique pour une caractérisation rapide des différents facies utilisés même après un incendie.
Commémorer et vénérer les martyrs de Perse : le témoignage des passions syriaques
Authors: Brelaud Simon 
Published: July 2023

La célébration des martyrs chrétiens, un des grands phénomènes de l’Antiquité tardive, a été bien étudiée pour l’ouest de l’Euphrate. Si elle n’a pas laissé de traces archéologiques remarquables dans les territoires de l’empire sassanide, l’historien peut s’appuyer néanmoins sur la littérature et notamment les actes des martyrs de Perse afin d’identifier les formes concrètes qu’a pu prendre ce culte dans le passé. Alors que la géographie ecclésiastique et administrative a longtemps intéressé les chercheurs s’appuyant sur l’hagiographie des martyrs de Perse, cet article suggère des pistes de recherche à partir du même corpus ; il vise à mesurer l’évolution géographique du culte des martyrs à travers les territoires perses, avant et après la conquête arabo-islamique. Une géographie mentale des espaces chers aux auteurs des passions syriaques révèle alors une évolution de la présence chrétienne jusqu’au début de l’époque abbasside. Les espaces ruraux et les régions isolées semblent de plus en plus valorisés, ce qui peut s’expliquer par la diffusion du monachisme perse, mais peut‑être aussi par le recul progressif de la présence chrétienne dans les plaines mésopotamiennes.
Al‑Ḥīra au croisement de traditions monastiques
Authors: Jullien Florence 
Published: July 2023

Au regard de la documentation spécialement syriaque, le paysage monastique de la région d’al‑Ḥīra apparaît à la fois multiple et complexe. Différentes formes de vie religieuse s’y sont incarnées en profondeur et dans la durée, dans une variété d’expressions, à la faveur de contextes politiques et socio-religieux propices, sur un espace-frontière réceptacle d’influences croisées. Cette prospection cherche à identifier les principaux courants monastiques qui ont marqué le secteur, leurs spécificités, mais aussi leurs interférences, et montre le déploiement qui s’y produisit autour du viie siècle, qui eut pour corollaire un façonnement de traditions accréditant une stratégie d’appropriation de l’espace.
Gestion des déchets, recyclage et qualité de l’emploi
Authors: Baguelin Olivier , Beir Jean De , Sourisseau Sylvain 
Published: July 2023

La gestion des déchets est centrale dans la transition écologique ; l’étude de ce secteur est donc particulièrement éclairante pour saisir les enjeux de cette transition, notamment en termes d’emploi. Le présent article applique les techniques de la statistique exploratoire aux données sectorielles de l’Insee (Ésane, Alisse) pour mener une analyse comparée, sur la décennie 2010, des diverses activités de gestion des déchets. On considère plus particulièrement deux activités aux implications écologiques opposées : le traitement-élimination (mise en décharge ou incinération, modalité brune) et la récupération-recyclage (modalité verte). En dépit d’interventions publiques favorables à la seconde activité, celle-ci présentait jusqu’en 2015 un emploi de moins bonne qualité. Cela tenait probablement aux économies d’échelle dont bénéficie le traitement-élimination. Elles lui permettaient une productivité du travail et une rémunération du capital supérieures, ces atouts encourageant l’investissement d’opérateurs privés. Sur la décennie 2010, si les deux activités ont en commun un emploi peu dynamique, le traitement-élimination concentre sa masse salariale sur des postes d’ouvriers qualifiés et de techniciens, en lien avec un effort d’équipement visant la production d’énergie. L’analyse met donc au premier plan le rôle de l’investissement dans la qualité de l’emploi.
Quelle professionnalisation dans le réemploi des déchets ?
Authors: Celle Sylvain 
Published: July 2023

Les ressourceries sont aujourd’hui des acteurs importants du réemploi des déchets. Étant majoritairement des associations d’insertion par l’activité économique, elles participent aussi au réemploi des personnes (chômeurs, etc.). Dans ce secteur pionnier dans les solutions pour économiser et réemployer les ressources, la précarité du travail et de l’emploi est encore prédominante. Pour y remédier, les ressourceries revendiquent la professionnalisation du travail de réemploi. Cet article s’intéresse à cette professionnalisation à partir d’une étude de cas, les Ateliers de la Bergerette. Cette association a contribué à valoriser le travail de réemploi par son rôle précurseur dans l’invention du modèle de « recyclerie », mais aussi en défendant, en son sein, des emplois durables et l’autogestion du travail.
The Interaction of Borrelia burgdorferi with Human Dendritic Cells: Functional Implications
Authors: Gutierrez-Hoffmann Maria , Fan Jinshui , O’Meally Robert N , Cole Robert N , Florea Liliana , Antonescu Corina , Talbot C Conover , Tiniakou Eleni , Darrah Erika , Soloski Mark J 
Published: July 2023

Abstract
Dendritic cells bridge the innate and adaptive immune responses by serving as sensors of infection and as the primary APCs responsible for the initiation of the T cell response against invading pathogens. The naive T cell activation requires the following three key signals to be delivered from dendritic cells: engagement of the TCR by peptide Ags bound to MHC molecules (signal 1), engagement of costimulatory molecules on both cell types (signal 2), and expression of polarizing cytokines (signal 3). Initial interactions between Borrelia burgdorferi, the causative agent of Lyme disease, and dendritic cells remain largely unexplored. To address this gap in knowledge, we cultured live B. burgdorferi with monocyte-derived dendritic cells (mo-DCs) from healthy donors to examine the bacterial immunopeptidome associated with HLA-DR. In parallel, we examined changes in the expression of key costimulatory and regulatory molecules as well as profiled the cytokines released by dendritic cells when exposed to live spirochetes. RNA-sequencing studies on B. burgdorferi–pulsed dendritic cells show a unique gene expression signature associated with B. burgdorferi stimulation that differs from stimulation with lipoteichoic acid, a TLR2 agonist. These studies revealed that exposure of mo-DCs to live B. burgdorferi drives the expression of both pro- and anti-inflammatory cytokines as well as immunoregulatory molecules (e.g., PD-L1, IDO1, Tim3). Collectively, these studies indicate that the interaction of live B. burgdorferi with mo-DCs promotes a unique mature DC phenotype that likely impacts the nature of the adaptive T cell response generated in human Lyme disease.
Factors associated with knowledge of diagnosis, prognosis & distress in cancer patients receiving palliative care – A retrospective cohort analysis
Authors: Deenadayalan Sathish Kumar , Balakrishnan Kalpana , Chidambaram Sundaramoorthy 
Published: July 2023

Background & objectives:
Demographic attributes of cancer patients are associated with the awareness of diagnosis, the prognosis of cancer and their associated psychological distress. This study was aimed to assess the knowledge of diagnosis, prognosis and psychological distress among patients reporting to the pain and palliative care department in a tertiary cancer hospital, south India.

Methods:
Data of all patients visiting the palliative care outpatient department of a tertiary cancer centre in south India between January and June 2018 were included in the study (n=754). A structured pro forma was used to collect information on the sociodemographic details and clinical aspects and a distress thermometer was used to assess the level of distress. Information, thus collected, were analysed using descriptive statistics and logistic regression.

Results:
Around 16.2 per cent of the patients were unaware of their diagnosis while two third (68%) were unaware of the prognosis. More than half of the patients reported significant distress (54.1%). Gender, education, not working and being diagnosed with head-and-neck cancers were associated with knowledge of diagnosis, while educational level predicted the knowledge of prognosis. Younger age group, head-and-neck cancer, haematology cancer, state of being unaware of diagnosis and prognosis were found to be associated with distress.

Interpretation & conclusions:
Higher educational levels and better socio-economic status increase the likelihood of patients being aware of their diagnosis and prognosis. Being unaware of the prognosis remains associated with the higher level of distress.
Costs & outcomes of hospitalized scrub typhus infection in a tertiary hospital in south India
Authors: John Kevin John , George Tarun K. , Joy Melvin , John Bimi , Abraham O.C. , Prasad Jasmine 
Published: July 2023

Background & objectives:
Scrub typhus is a rickettsial infection seen along the Asian-Pacific rim and imposes a considerable burden on affected people in low- and middle-income countries. The present study was aimed to determine the direct cost of hospitalization of scrub typhus and its trend over six years.

Methods:
This was a retrospective, observational, hospital based study of individuals admitted to the hospital, diagnosed with scrub typhus over six years, from January 2013 to December 2018. The potential out of pocket expenditure was evaluated.

Results:
A total of 198 patients were included in the study. The median cost of admission (adjusted to INR 2020) for the six years (2013 to 2018) was found to be

JOURNAL/ijmer/04.03/02223309-202306000-00010/559FF03/v/2023-09-02T030054Z/r/image-tiff

37,026 (US $ 490) [interquartile range (IQR) 22,996-64,992]. The median cost for patients admitted to the intensive care unit (ICU) was

JOURNAL/ijmer/04.03/02223309-202306000-00010/559FF03/v/2023-09-02T030054Z/r/image-tiff

128,046 (US $ 1695) (IQR 71,575-201,171), while the cost for patients admitted to the ward-alone was

JOURNAL/ijmer/04.03/02223309-202306000-00010/559FF03/v/2023-09-02T030054Z/r/image-tiff

33,232 (US $ 440) (IQR 19,609-45,373). The multivariable analysis showed that ARDS and SOFA score were the independent predictors of ICU admission.

Interpretation & conclusions:
Hospitalisation for scrub typhus is associated with a substantial healthcare expense. The predictors of increased cost were the presence of acute respiratory distress syndrome (ARDS), shock, increasing sequential organ failure assessment (SOFA) score and duration of hospital stay.
Good anesthetic for good esthetic: Blocks in oculoplasty
Authors: Christy Marem Chionkhumi , Honavar Santosh G , Talloju Shiva Shankar 
Published: July 2023

Background:
A good anesthesia not only makes the patient comfortable during surgery, but also has a huge impact on the postoperative recovery. It also makes the operating surgeon carry out each step of the surgery precisely and beautifully. The art of giving a good local anesthesia is to be learnt and practiced not only by anesthetists, but also by the practicing ophthalmologists.

Purpose:
This video gives an overview of anatomy in terms of the nerve supply of the orbit, the surface marking, and the techniques of giving regional and nerve blocks.

Synopsis:
In this video, we describe the anatomy, the surface marking, the technique of regional anesthesia including peribulbar, retrobulbar, and subtenon blocks and of nerve blocks, specifically of facial, frontal nerve and its branches, infraorbital, nasociliary, infratrochlear, and dorsal nasal nerves, with their application in ocular plastic surgery.

Highlights:
This video highlights the essence of providing appropriate and good anesthesia so that the surgeon works in an optimal field with maximum comfort to the patients.

Video link:
https://youtu.be/h8EgTMQAsyE

Key words: Blocks, oculoplasty, anaesthesia
Pigmented lesions of the conjunctiva: The sheep and the wolf
Authors: Christy Marem C , Honavar Santosh G , Mulay Kaustubh , Talloju Shiva Shankar 
Published: July 2023

Background:
Pigmented lesions in the conjunctiva can be baffling to both the patients and the treating ophthalmologist because of their varied range of presentation and overlapping clinical features. The lesions range from incidental pigment deposition such as mascara and complexion-associated melanosis to malignant melanoma which poses a risk to life. Similarly, the management ranges from observation at regular intervals to aggressive surgery like exenteration.

Purpose:
We wanted to present a crisp and precise video of the good, bad, and ugly pigmented lesions of the conjunctiva, highlighting their specific clinical features important for the diagnosis and their management.

Synopsis:
This video describes the myriad of pigmented conjunctival lesions, their diagnostic characteristics, and management based on oncological principles.

Link:

https://drive.google.com/file/d/1BYJ51rQtqjwM6e73BwrrLqdC1EoXA8Eu/view?usp=sharing.

Highlights:
Pigmented lesions can have variable presentation and close mimics, therefore, it is important to differentiate and identify the lesions accurately. This video highlights different pigmented lesions and their individual characteristic features.

Video link:
https://youtu.be/m9tt7dx9SWc

Key words: Conjunctiva, melanosis, nevus
Mean rate of progression of visual fields in patients with primary open-angle glaucoma and ocular hypertension attending a tertiary care center in South India – A prospective cohort study using FORUM® Glaucoma Workplace software
Authors: Smithin S S , Manju M , Chandran Premanand , Dhavalikar Mrunali , Menaka S V , Balagiri K , Venkataraman Ganesh 
Published: July 2023

Purpose:
To find out the mean rate of progression (MROP) of visual fields (VF) in patients with primary open-angle glaucoma (POAG) and ocular hypertension (OHT) using FORUM® Glaucoma Workplace.

Methods:
Two hundred and one eyes of 105 patients were included in this prospective cohort study. Patients with POAG and OHT were recruited, and VF analysis with 24-2 and or 10-2 was done using SITA standard strategy in Zeiss Humphrey Visual Field Analyzer (HFA). All the previous VFs were identified from FORUM software, and the baseline indices were recorded from the first reliable VF analysis. The present VF analysis was compared to the previous one using FORUM software, and the rate of progression (ROP) in VF was obtained by Guided Progression Analysis.

Results:
MROP of VF in the POAG group was − 0.085 dB/year, ranging from −2.8 to 2.8 dB/year with a standard deviation (SD) of 0.69. In the OHT group, the MROP of VF was −0.003 dB/year, ranging from − 0.8 to 0.5 dB/year with an SD of 0.27. The MROP of VF in medically treated eyes with POAG was −0.14 dB/year with an SD of 0.61 and in surgically treated eyes was −0.02 dB/year with an SD of 0.78. The overall baseline mean VF index (VFI) was 83.19% and the final mean VFI was 79.80%. There was a statistically significant decrease in the mean VFI value from baseline to the final visit (P-value 0.0005).

Conclusion:
The mean ROP of VF in the POAG group was −0.085 dB/year and in the OHT group was − 0.003 dB/year.
Concomitant paracentral acute middle maculopathy and acute macular neuroretinopathy in eyes post-blunt trauma
Authors: Goel Nikita , D’ Souza Zubin , Tripathi Abhishek , Dey Amrita , Sen Ahana , Majumdar Bristi , Thounaojam Sanatombi , Roy Rupak , Saurabh Kumar 
Published: July 2023

Purpose:
To analyze the imaging characteristics and the clinical course of patients showing concomitant paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) post-blunt trauma.

Methods:
PAMM and AMN lesions post-blunt trauma diagnosed on enhanced depth imaging optical coherence tomography (EDI-OCT) were recruited for the study.

Results:
Thirteen eyes of 13 individuals with a history of blunt trauma were included in the study, of whom 11 (85%) were males. Mean age of the patients was 33.62 (range 16–67) years. Mean visual acuity at presentation and the last visit was 1.67 log of minimum angle of resolution (logMAR) and 0.82 logMAR, respectively. Mean interval between trauma and imaging was 5.08 (range 1–15) days. All patients had unilateral involvement, with the right eye being involved in 10 patients (77%). All patients had concomitant PAMM and AMN lesions.

Conclusion:
Presence of coincident PAMM and AMN suggests a common pathophysiologic etiology, but the description of concomitant PAMM and AMN in the setting of blunt trauma to eye is hitherto unreported. Identifying AMN in a setting of PAMM requires meticulous examination of the OCT and OCTA images. It can be a cause of suboptimal visual recovery in such eyes.
Social-emotional issues among children with strabismus higher than among non-strabismus children in Western India
Authors: Prem Kumar SG , Ranpise Dhanaji , Vishwakarma Pankaj , Gend Pravin B , Chavan Shobhana , Kurian Elizabeth 
Published: July 2023

Purpose:
Data on social-emotional aspects among children with strabismus in India are scanty. We compared the emotional symptoms (ES), loneliness and social dissatisfaction (LSD), and self-esteem (SE) and their associated risk factors among children with and without strabismus in India.

Methods:
A cross-sectional case–control study design was used to recruit 101 children with strabismus aged 8 to 18 years and a control group of 101 children that were age- and gender-matched. Interviews were performed using standardized scales to assess ES, LSD, and SE. Variations in the intensity of ES, LSD, and SE were assessed using multiple classification analysis (MCA).

Results:
A total of 202 children participated in the study. The mean ES, LSD, and SE scores were 3.4 (standard deviation [SD] 1.9), 48.4 (SD 3.2), and 22.1 (SD 3.8) for the strabismus group and 1.8 (SD 1.5), 33.3 (SD 3), and 31.3 (SD 2) for the non-strabismus group, respectively. Among the strabismus group, the highest levels of mean ES, LSD, and SE scores were observed among children facing problems in performing daily tasks. Amongst the non-strabismus group, children studying at the primary level and those facing neglect had the highest mean scores. In MCA, being affected with strabismus had the highest effect on the intensity of ES, LSD, and SE with a beta (b) value of 0.223 (P = 0.016), 0.922 (P < 0.001), and 0.853 (P < 0.001).

Conclusion:
A significantly high proportion of children with strabismus deal with elevated levels of ES, LSD problems, and low SE as compared with non-strabismus children, highlighting the need to address the poor social-emotional health of children.