bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemanfaatan Limbah Rumah Tangga Berbasis Eco Enzyme dan Aplikasinya dalam Pembuatan Liquid Detergent di SMAN 1 Parakan Salak, Sukabumi
Authors: Rizkita Aden Dhana , Saputra Reza Pratama , Firmansyah Azhari 
Published: March 2023

Eco enzyme adalah cara mengolah limbah sampah menjadi produk yang bermanfaat secara efektif. Eco enzyme atau garbage enzyme adalah cairan hasil fermentasi sampah organik seperti sisa-sisa sayuran dan buah-buahan yang belum busuk. Tahap pertama pada saat memulai kegiatan pengabdian kepada masyarakat dilakukan pemaparan materi, didalam pemaparan materi ditonjolkan tanya jawab seputar pengenalan eco enzyme, cara pembuatannya, kegunaannya, aplikasi dalam produk kefarmasian, dan pemilihan bahan baku limbah rumah tangga. Pada pengabdian masyarakat kali ini dapat dilihat hasil peningkatan pengetahuan tentang eco enzyme mulai dari pengertian, cara pembuatan, fungsinya, dan juga aplikasi yang bisa di buat dari grafik hasil pre tes dan post tes sebelum pemaparan materi. Hasil pengabdian kepada masyarakat menunjukan bahwa adanya peningkatan kemampuan yang dimiliki siswa dan guru SMAN 1 Parakan salak tentang pemanfaatan limbah menjadi Eco enzyme dan aplikasinya dalam pembuatan deterjen cair ditandai dengan peningkatan pengetahuan tentang definisi Eco enzyme dari 13,33% menjadi 86,66%., Pengetahuan tentang cara pembuatan Eco enzyme dari 6,67% menjadi 93,33%., Pengetahuan tentang pembuatan dteterjen cair dari 33,34% menjadi 100%.
Edukasi Proses Reintegrasi Bagi Korban Perdagangan Manusia di Kecamatan Sajingan Besar Kabupaten Sambas
Authors: Alunaza Hardi , Maryuni Sri , Suwarso Widha Anistya , Rusdiono  , Pardi Pardi , Umniyah Annisa , Cantika Suci 
Published: March 2023

Kegiatan pengabdian ini dilaksanakan di Kecamatan Sajingan Besar mengusung tema proses reintegrasi bagi bagi korban perdagangan orang. Kegiatan pengabdian ini dilaksanakan mulai dari September hingga Oktober dengan bentuk pelaksanaan kegiatan terdiri dari ceramah penyampaian materi, sosialisasi, diskusi dengar pendapat. Sementara evaluasi yang dilakukan dalam kegiatan PKM berbentuk analisis hasil pelaksanaan dalam bentuk analisis kuantitatif dari diskusi dengar pendapat. Berdasarkan kegiatan pengabdian yang dilaksanakan di Desa Sebunga Kecamatan Sajingan Besar, dapat disimpulkan bahwa masyarakat masih belum mengetahui dan memiliki pemahaman yang baik mengenai proses reintegrasi yang seharusnya diterima oleh korban perdagangan manusia. Namun, sosialisasi dan edukasi yang diberikan oleh tim pengabdian dapat membantu masyarakat dalam memahami bentuk perlindungan terhadap kejahatan perdagangan orang. Masyarakat juga mendapatkan edukasi yang baik terkait identifikasi korban, proses recovery, rehabilitasi sosial hingga proses reintegrasi secara komprehensif.
Penyuluhan Peningkatan Akreditasi RS Dengan Kepuasan Pasien Pada Pelayanan Rehabilitatif Dalam Masyarakat
Authors: Kusumawardhani Oktavy Budi , Widyastuti Kristina , Rejeki Mirah 
Published: March 2023

Akreditasi adalah komitmen wajib rumah sakit (RS) dalam peningkatan keselamatan & kesehatan pasien. Lingkungan pelayanan rumah sakit aman dan minim risiko untuk pasien serta staf RS. Penyuluhan ditujukan untuk meningkatkan upaya sosialisasi Akreditasi RS dengan kepuasan pasien pada pelayanan rehabilitative dalam masyarakat. Pengabdian ini dilakukan secara offline dan sasaran pada pasien serta masyarakat pengguna rumah sakit. Didapatkan nilai hasil 7,760848 (t hitung) > 2,048 (t table) dari perbandingan t hitung > t table dapat disimpulkan maka data sign untuk taraf signifikansi 0,05%. Dari uji sign dapat diketahui sosialisasi peningkatan akreditasi RS dengan kepuasan pasien pada pelayanan rehabilitative dalam masyarakat menunjukkan adanya peningkatan hasil dan menunjukkan bahwa sosialisasi peningkatan Akreditasi RS dengan kepuasan pasien pada pelayanan rehabilitative dalam masyarakat meningkatkan pengetahuan peserta. Penelitian dapat meningkatkan sosialisasi upaya akreditasi RS dengan kepuasan pasien pada pelayanan rehabilitative dalam masyarakat.
Peningkatan Kemampuan Menghitung BEP dan Pemasaran Melalui E-Commerce pada Usaha ”Aprilla Puding and Cake”
Authors: Robiansyah Anton , Daurrohmah Eka Wirajuang , Suryani Pesi , Kharis Selly Anastassia Amellia , Zubir Edward 
Published: March 2023

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan mahasiswa dalam menghitung Break Event Point (BEP) dan cara memasarkan produk melalui marketplace. Kegiatan dilaksanakan melalui pelatihan dan pendampingan, tahap pertama dilakukan pelatihan menghitung Break Event Point (BEP) dan penyusunan laporan keuangan, pelatihan membuat packaging atau kemasan yang menarik, dan pelatihan pemasaran produk melalui e-commerce. Tahap kedua dilakukan pendampingan perhitungan BEP dan pembuatan packaging yang menarik. Setelah mengikuti kegiatan ini diharapkan mitra dapat menghitung BEP produknya dengan tepat, mampu membuat packaging yang menarik dan mampu memasarkan produknya melalui marketplace sehingga dapat meningkatkan penjualan produk. Mitra dalam kegiatan pengabdian ini adalah unit UMKM milik mahasiswa Jurusan Akuntansi UPBJJ-UT Jakarta yang bernama Isnaini Ulfa Aprilla dengan nama usaha “Aprilla Pudding and Cake”. Luaran yang yang diharapkan dari kegiatan PkM ini adalah adanya peningkatan omset penjualan, kualitas packaging produk dan kemampuan marketing mitra.
Sosialisasi Penggunaan Tool Mendeley Kepada Mahasiswa STIE Ganesha
Authors: Saefullah Aep , Candra Hendra , Agustina Ika , Syahreza Arief , Fatahillah Umar Syahid , Misbah Ibah 
Published: March 2023

Menghindari budaya plagiat memerlukan upaya dan komitmen semua pihak. Pengabdian masyarakat ini bertujuan memberikan pengetahuan kepada 85 mahasiswa STIE Ganesha penggunaan aplikasi mendeley. Kegiatan berlangsung selama empat bulan dari Oktober 2022 hingga Januari 2023 melalui sosialiasi, pelatihan, ceramah, diskusi, pre-test, post test dan praktikum langsung. Hasil penelitian bahwa mahasiswa mengapresiasi kegiatan dengan baik dan positif ditandai dengan antuasiasnya selama kegiatan. Kegiatan ini bermanfaat dan turut membantu mahasiswa dalam tugas perkuliahan. Mahasiswa lebih produktif dalam membuat karya tulis ilmiah. Mahasiswa dapat praktik langsung dan mengoperasikan mendeley mulai mendownload aplikasi, mencari daftar pustaka dan menginput sumber berbagai refrensi baik dari buku, jurnal, dan situs. Kendala yang ditemukan yaitu mahasiswa tidak konsisten dalam penggunaan mendeley, oleh karena itu diperlukan pendampingan dosen yang berkelanjutan pasca kegiatan sosialisasi. Peran dosen sangat signifikan untuk meningkatkan kualitas karya ilmiah mahasiswa. Pihak kampus perlu membuat program guna menunjang skill menulis mahasiswa seperti coaching dan workshop penulisan karya ilmiah.
New technologies in the surgical management of endometriosis
Authors: Massimello Francesca , Di Spiezio Sardo Attilio , Bifulco Giuseppe , Angioni Stefano , Cela Vito 
Published: March 2023

Introduction: Endometriosis is a very common disease that affects up to 10% of the female population. Although medical therapy represents the first-line treatment for endometriosis, it does not always manage to control symptoms. Laparoscopy represents the standard surgical treatment in endometriosis. Robotic-assisted laparoscopy is an innovative mini-invasive surgical technique. Its application in gynecological surgery and in endometriosis has increased in the last decade. Our purpose is to offer an overview of the role of robotic-assisted laparoscopy in the surgical treatment of endometriosis.
Methods: We evaluated studies dealing with the new technique in surgery for endometriosis with a focus on robotic surgery. We performed a compressive literature research on PubMed and the Cochrane Library in December 2022.
Expert opinion: Robotic-assisted surgery is a feasible and safe approach to endometriosis surgery and is superimposable to laparoscopy in terms of complication rate, blood loss, hospitalization, and long-term improvement of symptoms.
The effect of robotic-assisted surgery on operative time is still contradictory and needs to be further investigated. Robotic-assisted laparoscopic surgery can provide particular benefit in the management of women with severe endometriosis secondary to its advantage in surgical precision and ergonomics.
Indocyanine green fluorescence angiography could be useful to assist in the vascularization of ureters and bowel anastomosis, to prevent postoperative complication and leakage.
PEMBUATAN PROFIL INSTANSI BALAI PENYULUHAN PERTANIAN KECAMATAN BELIK BERBASIS WEB MENGGUNAKAN FRAMEWORK CODEIGNITER
Authors: Muhamad Zen Shidqi 
Published: March 2023

Belik Subdistrict Agricultural Extension Center (BPP Belik) is a government extension agency that fosters farmers in Belik village. Every month at BPP Belik many activities are carried out. Both indoor activities and outdoor activities. The PPL (Field Agricultural Extension) officers provide a lot of training and coaching to farmers in Belik Village. However, the involvement of the participating farmers is still very limited, considering that BPP Belik has very limited funds and time. This makes information not spread evenly to farmers in Belik Village. Dissemination of information in the form of training or articles evenly will certainly increase agricultural production. Based on the existing problems, it is necessary to have a new information system, namely the creation of a website profile of the Belik District Agricultural Extension Center as an effort to provide alternative solutions for PPLs in disseminating information to farmers.
The development of information systems on the website profile of the Belik District Agricultural Extension Center is using the waterfall method. Which consists of the analysis process, system design, design and implementation. The data analysis stage was obtained from interviews. Creating a website profile for BPP Belik agencies using the PHP programming language and MySql database. As well as using the php Codeigniter framework.
The system trial on the BPP Belik Agency profile website is using the black box method. This test was carried out by 2 admins and writers at BPP Belik. The tests carried out are testing the appearance / user interface on the admin page and on the main page of the website.
Social media and internet search data to inform drug utilization: A systematic scoping review
Authors: Keller Roman , Spanu Alessandra , Puhan Milo Alan , Flahault Antoine , Lovis Christian , Mütsch Margot , Beau-Lejdstrom Raphaelle 
Published: March 2023

IntroductionDrug utilization is currently assessed through traditional data sources such as big electronic medical records (EMRs) databases, surveys, and medication sales. Social media and internet data have been reported to provide more accessible and more timely access to medications' utilization.ObjectiveThis review aims at providing evidence comparing web data on drug utilization to other sources before the COVID-19 pandemic.MethodsWe searched Medline, EMBASE, Web of Science, and Scopus until November 25th, 2019, using a predefined search strategy. Two independent reviewers conducted screening and data extraction.ResultsOf 6,563 (64%) deduplicated publications retrieved, 14 (0.2%) were included. All studies showed positive associations between drug utilization information from web and comparison data using very different methods. A total of nine (64%) studies found positive linear correlations in drug utilization between web and comparison data. Five studies reported association using other methods: One study reported similar drug popularity rankings using both data sources. Two studies developed prediction models for future drug consumption, including both web and comparison data, and two studies conducted ecological analyses but did not quantitatively compare data sources. According to the STROBE, RECORD, and RECORD-PE checklists, overall reporting quality was mediocre. Many items were left blank as they were out of scope for the type of study investigated.ConclusionOur results demonstrate the potential of web data for assessing drug utilization, although the field is still in a nascent period of investigation. Ultimately, social media and internet search data could be used to get a quick preliminary quantification of drug use in real time. Additional studies on the topic should use more standardized methodologies on different sets of drugs in order to confirm these findings. In addition, currently available checklists for study quality of reporting would need to be adapted to these new sources of scientific information.
Association of obesity with the development of end stage renal disease in IgA nephropathy patients
Authors: Wang Siqing , Qin Aiya , Dong Lingqiu , Tan Jiaxing , Zhou Xiaoyuan , Qin Wei 
Published: March 2023

Background and aimImmunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. We aimed to evaluate whether obesity is a risk factor for IgAN patients.MethodsA total of 1054 biopsy-proven IgAN patients were analyzed in this retrospective study. Patients were divided into four groups according to their body weight index (BMI) at the period of renal biopsy: underweight group (BMI&lt; 18.5, N=75), normal weight group (18.5≤BMI&lt;24, N=587), overweight group (24≤BMI&lt;28, N=291) and obesity group (28≤BMI, N=101). The endpoint of our study was end stage renal disease (ESRD: eGFR &lt;15 mL/min/1.73 m2 or having renal replacement treatment). Kaplan-Meier analyses and Cox proportional hazard models were performed to evaluate renal survival. Propensity-score matching (PSM) was performed to get the matched cohort to evaluate the role of obesity in IgAN patients. Besides, the effect modification of obesity and hypertension in IgAN patients was clarified by the synergy index.ResultsIgAN patients complicated with obesity had more severe renal dysfunction at the time of renal biopsy than those with optimal body weight. In addition, patients with obesity tended to have higher risk of metabolic disorders, such as hyperuricemia (64.4% vs 37%, p&lt;0.001), hypertriglyceridemia (71.3% vs 32.5%, p&lt;0.001) and hypercholesterolemia (46.5% vs 35.6%, p=0.036). It was observed that obesity patients had higher rate of unhealthy behaviors, such as smoking (27.7% vs 16.4%, p=0.006) and alcohol drinking (29.7% vs 19.9%, p=0.027). Although obesity was not confirmed as an independent risk factor for IgAN patients, we found that IgAN patients with obesity presented with higher incidence of hypertension, as well as lower event-free renal survival rate (log-rank p &lt; 0.001), especially in patients with 24-h urine protein ≥ 1g (log-rank p =0.002). In addition, the synergy index showed that there was positive interaction between obesity and hypertension in IgAN.ConclusionObesity is an important risk factor for IgAN patients when combined with hypertension. Hypertension appears to be common in obese IgAN patients.
Study on the influence of magnetic field on the performance of a 5 kW hall thruster
Authors: Yang L. , Wang P. Y. , Wang T. 
Published: March 2023

Hall thruster is a kind of plasma optics device, which is used mainly in space propulsion. To study the influence of magnetic field on the performance of a 5 kW hall thruster, a two-dimensional PIC-MCC model was built. The Bohm diffusion was modeled by using a Brownian motion instead of the Bohm collision method and the near-wall conduction was modeled by a secondary electron emission model. When the mass flow rate is 5 mg/s, the thruster performance like thrust, efficiency and discharge current was simulated under a discharge voltage from 300 to 1,000 voltage. At first, the performance under constant magnetic field was simulated. The results showed that the magnetic field could not restrain the electrons as the discharge voltage increased. Later, the performance under varied magnetic field was simulated. The results showed that increasing the magnetic field strength with the increasing discharge voltage could restrain the electrons more efficiently, which proved that increasing the magnetic field strength is necessary for high specific impulse operation of hall thruster. At last, the performance measurement experiment of the thruster was carried out, and the experimental results verified the accuracy of the simulation results.
The management of acne vulgaris in young people in primary care: A retrospective cohort study
Authors: Moosa Aminath Shiwaza , Lim Shu Fen , Koh Yi Ling Eileen , Aau Wai Keong , Tan Ngiap Chuan 
Published: March 2023

BackgroundAcne vulgaris (acne) is common among young persons (YPs). Clinical practice guidelines are available for acne management to minimize their physical and psychological impact. However, evidence of adherence to these guidelines is sparse in primary care practices. The study aimed to determine the demographic profile of YPs who sought primary care consultations for acne, their related prescriptions and referrals to specialists for further management.MethodA retrospective study was conducted using data from a cluster of eight public primary care clinics in Singapore. Demographic, clinical, prescription, and referral data were extracted from the electronic health records of YPs aged 10–29 years with a documented diagnosis of acne (ICD-10 classification) from 1st July 2018 to 30th June 2020. The data were reviewed, audited for eligibility criteria, and de-identified before analysis.ResultsComplete data from 2,700 YPs with acne were analyzed. Male (56.1%) YPs and those of Chinese ethnicity (73.8%) had the most frequent attendances for acne. The mean and median age at presentation was 19.2 (standard deviation = 4.3) and 19 (interquartile range = 16–22) years, respectively. Only 69.7% of YPs received an acne-related medication; 33.5% received antibiotic monotherapy; 53.0% were prescribed oral doxycycline, 35.0% acne cream (combination of sulfur, salicylic acid, and resorcinol), and 28.4% benzoyl peroxide 5% gel; 54.3% of those treated with antibiotics were prescribed with a shorter duration than recommended; 51.3% were referred to a dermatologist on their first visit, and 15.8% had more than one visit.ConclusionAcne management for YPs can be enhanced with refresher training among primary care physicians for better adherence to its clinical practice guidelines.
Fasting blood glucose-to-glycated hemoglobin ratio for evaluating clinical outcomes in patients with ischemic stroke
Authors: Shao Tengfei , Liu Hui , Yang Guochao , Wang Huan , Li Di , Ni Huanyu , Xu Yun , Zhang Jinping 
Published: March 2023

BackgroundStress hyperglycemia frequently occurs in patients with acute ischemic stroke (AIS). The influence of stress hyperglycemia on the outcomes of patients with AIS remains ambiguous.MethodsData from our institution on patients with AIS between June 2020 and June 2021 were retrospectively analyzed. The severity of the stroke was assessed using the National Institutes of Health Stroke Scale (NIHSS) at admission, and the primary endpoint was functional outcomes. Stress hyperglycemia was measured by the glucose-to-HbA1c ratio. In the multivariable analysis, two models that retained or excluded the NIHSS were adopted to explore the relationship between stress hyperglycemia and outcomes. The receiver operating characteristic curve (ROC) was calculated to determine an optimized cutoff value.ResultsThe optimal cutoff value was 1.135. When all patients were included, model 1 did not find an association between the glucose-to-HbA1c ratio and functional outcomes. In model 2, the glucose-to-HbA1c ratio×10 (Glucose-to-HbA1c ratio ×10) was the independent predictor of functional outcomes (OR 1.19, 95% CI 1.07–1.33, p &lt; 0.01). Separately, in patients without diabetes, the glucose-to-HbA1c ratio×10 was the independent predictor of functional outcomes in both model 1 (OR 1.37, 95% CI 1.08–1.73, p = 0.01) and model 2 (OR 1.48, 95% CI 1.22–1.79, p &lt; 0.01), but not in patients with diabetes. In addition, the glucose-to-HbA1c ratio×10 was the independent predictor of stroke severity (OR 1.16, 95% CI 1.05–1.28, p &lt; 0.01).ConclusionThe glucose-to-HbA1c ratio was associated with more severe AIS. Specifically, the glucose-to-HbA1c ratio was associated with the functional outcomes in patients without diabetes but not in patients with diabetes.
Copeptin adaptive response to SGLT2 inhibitors in patients with type 2 diabetes mellitus: The GliRACo study
Authors: Berton Alessandro Maria , Parasiliti-Caprino Mirko , Prencipe Nunzia , Bioletto Fabio , Lopez Chiara , Bona Chiara , Caputo Marina , Rumbolo Francesca , Ponzetto Federico , Settanni Fabio , Gasco Valentina , Mengozzi Giulio , Ghigo Ezio , Grottoli Silvia , Maccario Mauro , Benso Andrea Silvio 
Published: March 2023

IntroductionIn type 2 diabetes mellitus (T2DM), the antidiuretic system participates in the adaptation to osmotic diuresis further increasing urinary osmolality by reducing the electrolyte-free water clearance. Sodium glucose co-transporter type 2 inhibitors (SGLT2i) emphasize this mechanism, promoting persistent glycosuria and natriuresis, but also induce a greater reduction of interstitial fluids than traditional diuretics. The preservation of osmotic homeostasis is the main task of the antidiuretic system and, in turn, intracellular dehydration the main drive to vasopressin (AVP) secretion. Copeptin is a stable fragment of the AVP precursor co-secreted with AVP in an equimolar amount.AimTo investigate the copeptin adaptive response to SGLT2i, as well as the induced changes in body fluid distribution in T2DM patients.MethodsThe GliRACo study was a prospective, multicenter, observational research. Twenty-six consecutive adult patients with T2DM were recruited and randomly assigned to empagliflozin or dapagliflozin treatment. Copeptin, plasma renin activity, aldosterone and natriuretic peptides were evaluated at baseline (T0) and then 30 (T30) and 90 days (T90) after SGLT2i starting. Bioelectrical impedance vector analysis (BIVA) and ambulatory blood pressure monitoring were performed at T0 and T90.ResultsAmong endocrine biomarkers, only copeptin increased at T30, showing subsequent stability (7.5 pmol/L at T0, 9.8 pmol/L at T30, 9.5 pmol/L at T90; p = 0.001). BIVA recorded an overall tendency to dehydration at T90 with a stable proportion between extra- and intracellular fluid volumes. Twelve patients (46.1%) had a BIVA overhydration pattern at baseline and 7 of them (58.3%) resolved this condition at T90. Total body water content, extra and intracellular fluid changes were significantly affected by the underlying overhydration condition (p &lt; 0.001), while copeptin did not.ConclusionIn patients with T2DM, SGLT2i promote the release of AVP, thus compensating for persistent osmotic diuresis. This mainly occurs because of a proportional dehydration process between intra and extracellular fluid (i.e., intracellular dehydration rather than extracellular dehydration). The extent of fluid reduction, but not the copeptin response, is affected by the patient’s baseline volume conditions.Clinical trial registrationClinicaltrials.gov, identifier NCT03917758.