bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of calf muscular vein thrombosis on the prognosis within one year postoperatively of geriatric hip fracture patients: a propensity score-matched analysis
Authors: Jiang Jiabao , Xing Fei , Luo Rong , Chen Zhao , Liu Hao , Duan Xin , Xiang Zhou 
Published: May 2023

Abstract
Introduction:
Calf muscular vein thrombosis (CMVT) is a type of distal deep vein thrombosis, which is common in geriatric hip fracture patients. However, studies focusing on whether the orthopedic operation has an impact on the prognosis of geriatric hip fracture patients with CMVT are very limited. Therefore, the aim of this study was to explore whether geriatric hip fractures with CMVT affect the mortality of patients within one year postoperatively. The difficulty of the operation, postoperative complications, the status of thrombosis, and long-term function were also compared.
Materials and Methods
Geriatric hip fracture patients who underwent surgery between January 2019 and January 2021 were included. Patients were divided into groups with and without CMVT by preoperative color Doppler ultrasound examination. Propensity score-matching (PSM) was performed in a ratio of 1:1 between the patient with and without CMVT groups. Baseline characteristics, laboratory results, perioperative indicators and prognosis of patients were collected retrospectively. Intraoperative and long-term postoperative comparisons were conducted between patients with and without CMVT.
Results
Two hundred and sixty geriatric hip fracture patients were included. Eighty-nine patients in each group were matched after PSM. There was no significant difference in mortality between the two groups at one-month, three-month, six-month, and one-year postoperatively. However, patients with CMVT had longer hospital stays, a higher incidence of postoperative complications, and a higher incidence of thrombosis progression than patients without CMVT in long-term follow-up.
Conclusion
CMVT in Chinese geriatric hip fracture patients is not associated with mortality within one year postoperatively. In addition, when orthopedic surgeons treat geriatric hip fracture patients with CMVT, enhanced postoperative rehabilitation, meticulous nursing, and thrombosis management are recommended to achieve better clinical outcomes and long-term prognosis.
Trial registration:
Chinese Clinical Trial Registry (ChiCTR2300069411). Registered March 15, 2023, https://www.chictr.org.cn/showproj.html?proj=192079
4CAC: 4-class classifier of metagenome contigs using machine learning and assembly graphs
Authors: Pu Lianrong , Shamir Ron 
Published: May 2023

Abstract
Microbial communities usually harbor a mix of bacteria, archaea, phages, plasmids, and microeukaryotes. Phages, plasmids, and microeukaryotes, which are present in low abundance in microbial communities, have complex interactions with bacteria and play important roles in horizontal gene transfer and antibiotic resistance. However, due to the difficulty of identifying phages, plasmids, and microeukaryotes in microbial communities, our understanding of these minor classes lags behind that of bacteria and archaea. Recently, several classifiers have been developed to separate one or two minor classes from bacteria and archaea in metagenome assemblies, but none can classify all of the four classes simultaneously. Moreover, existing classifiers have low precision on minor classes.
Here, we developed for the first time a classifier called 4CAC that is able to identify phages, plasmids, microeukaryotes, and prokaryotes simultaneously from metagenome assemblies. 4CAC generates an initial four-way classification using several sequence length-adjusted XGBoost algorithms and further improves the classification using the assembly graph. Evaluation on simulated and real metagenome datasets demonstrates that 4CAC substantially outperforms existing classifiers and combinations thereof on short reads. On long reads, it also shows an advantage unless the abundance of the minor classes is very low. 4CAC runs 1-2 orders of magnitude faster than the other classifiers. The 4CAC software is available at https://github.com/Shamir-Lab/4CAC.
An Alternating Direction Implicit Finite Element Galerkin Method for the Linear Schrödinger Equation
Authors: Khebchareon Morrakot , Pani Amiya , Fairweather Graeme , Fernandes Ryan 
Published: May 2023

Abstract
We formulate and analyze a fully-discrete approximate solution of the linear Schrödinger equation on the unit square written as a Schrödinger-type system. The finite element Galerkin method is used for the spatial discretization, and the time-stepping is done with an alternating direction implicit extrapolated Crank-Nicolson method. We demonstrate the existence and uniqueness of the approximation, and prove that the scheme is of optimal accuracy in the L2 , H1 and L∞ norms in space and second–order accurate in time. Numerical results are presented which support the theory.
Policy, system and service design influence on healthcare inequities for people with end-of-life chronic obstructive airways disease, their support people and health professionals.
Authors: Landers Amanda , Pitama Suzanne G , Palmer Suetonia C , Beckert Lutz 
Published: May 2023

AbstractBackground: People with end-of-life chronic obstructive pulmonary disease (COPD) experience debilitating physical limitations, with a high mortality rate. Our research has shown health system design and delivery leads to inequitable outcomes. Enabling people with end-of-life COPD, their support people, and health professionals to partner in setting the agenda for resource allocation may inform health service improvement.Design: Qualitative methodology utilising focus groups including patients, family, friends, informal support people, health care workers and professionals.Methods: The analysis, utilising critical theory and Actor-Network theory, positioned people with severe COPD, their support people and health professionals as experts in end-of-life care. Analyses triangulated these perspectives, and were reviewed by the research investigators and an expert reference group.Results: Participants (n=74) in seven focus groups reported their experiences of inequity within the healthcare system. Equity was an overarching phenomenon identified by participants, with three specific themes being described: policy design, system design, and service design.Conclusion: Experiences of patients, their support people and health professionals as experts in end-of-life COPD care can inform health systems and health service design to address current inequities in funding and delivery of care for end-of-life COPD.
Success factors of telemedicine startup in Vietnam: the roadmap to transform healthcare customer behavior
Authors: Long Hoang Cuu , Thuan Do Le Duc 
Published: May 2023

Abstract
Telemedicine has become a breakthrough solution in improving access to healthcare services. In Vietnam, telemedicine is the key national program which was motivated to develop by the ministry of health and the government. However, the implementation process encountered many challenges and the number of successful businesses in this field was still limited. This study integrated the technology acceptance model and the extended valance framework to develop an efficient behavioral model for investigating the relationship among trust in provider, perceived ease of use, perceived benefit, perceived risk on usage intention. The proposed framework was verified by in depth interview with three experts in Vietnam health technology market and was tested by 246 participants via web-based survey. Generally, the findings showed that perceived ease of use, perceived benefit positively and significantly affected the usage intention, while perceived risk negatively and significantly influenced the usage intention. Trust in provider positively and significantly influenced the usage intention and perceived benefit, but negatively influenced perceived risk (β = -0.677, p = 0.000). Perceived ease of use significantly and positively affected perceived benefit, while the effect of perceived ease of use on perceived risk was not statistically significant (p = 0.128). The proposed hypothetical model offered empirical insights to healthcare professionals, service providers and authorities. Moreover, it could serve as a theoretical basis for future researches.
Electrochemical Determination of Endrin from Fruit Juice Samples at Glassy Carbon Electrode Modified with Fe Doped ZnO Nanomaterial
Authors: Teshome Toleshi , Kitte Shimeles Addisu , Gonfa Guta , Gure Abera 
Published: May 2023

Abstract
In this study, iron doped ZnO nanomaterial was synthesized by co-precipitation method and its surface properties were studied using Fourier transform infrared (FTIR), X-ray diffraction (XRD), Scanning electron microscopy (SEM) and UV-Vis spectroscopy. The characterization results confirmed that the synthesized Fe-ZnO nanoparticle exhibits good crystalline nature possessing wurtzite hexagonal phase and good optical properties. The synthesized Fe-ZnO nanomaterial modified glassy carbon electrode (Fe-ZnO/GCE) was used for the electrochemical determination of endrin pesticide in fruit juice samples. Compared to the bare glassy carbon electrode, the modified electrode, Fe-ZnO/GCE, showed remarkable electro-catalytic properties and an enhanced sensitivity for the determination of target analyte. It also exhibited a good linear response to endrin in the concentration ranging from 0.1 to 70 µM. The limit of detection (LOD) and limit of quantification (LOQ) of the method were 0.019 µM and 0.065 µM, respectively. Moreover, Fe-ZnO/GCE was selective for endrin analysis. It has also showed long-term stability, good repeatability and within-lab reproducibility. The practical utility of Fe-ZnO/GCE was applied for the determination of endrin in mango and orange juice samples. The relative recoveries of the real samples were ranged from 91.4-106.5%. The developed method could be used as good candidate for monitoring of endrin pesticides in food samples and other similar matrixes.
Prognostic value of lymphocyte-to-C-reactive-protein ratio in cancers
Authors: Liu Rongqiang , Ma Wangbin , Zi Liuliu , Zhang Lilong , Qiu Zhengdong , Wang Kunpeng , Zhao Kailiang , Hu Baohong , Wang Weixing 
Published: May 2023

Abstract
Background
Systemic inflammation and immune nutritional status affect tumor progression and patient survival. Lymphocyte-to-C-reactive-protein ratio(LCR) as inflammatory immune index has been reported to be associated with prognosis of various cancers. However, the results are controversial. Therefore, the aim of this study was to comprehensively evaluate the clinical value of LCR in cancers through a meta-analysis.
Methods
A comprehensive search of relevant studies was performed by scrutinizing the databases until March 31, 2023. The pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated to evaluate overall survival (OS), disease-free survival (DFS), recurrence free survival (RFS), progression-free survival (PFS) and cancer-specific survival (CSS).
Results
A total of 31 studies from 29 articles involving 11429 patients were included in the study. The pooled analysis showed that patients with high LCR was significantly associated with favorable OS (HR: 0.51,95% CI:0.48–0.55),DFS (HR: 0.55,95% CI:0.43–0.70),RFS (HR:0.57,95% CI:0.48–0.67),PFS (HR: 0.50,95% CI:0.27–0.92) and CSS (HR:0.53,95% CI:0.42–0.67).Sensitivity analysis confirmed the reliability of these results.
Conclusions
LCR can be used as an effective prognostic marker in cancers.
Influencing Factors of Art Painting Based on Computer Vision Technology
Authors: Cui Hanshi 
Published: May 2023

Abstract
In view of the problems existing in the artistic creation of modern art painting, such as poor composition, limited tools and materials, and improper color matching, this article proposed to apply computer vision technology to the art of art painting. Computer vision technology can simulate the visual process of living things, by sensing the environment, and using the relevant technologies contained therein to create two-dimensional (2D) images into three-dimensional (3D) information. Therefore, a comparative experiment was set up. The experimental results showed that when the sample images processed by computer vision technology were presented to the creator for viewing, the time taken by creator A and creator B to complete the artistic composition was 3.54 minutes and 3.66 minutes, respectively. When presenting the original unprocessed sample image to Creator C and Creator D for viewing, the time it took them to complete the artistic composition was 7.31 minutes and 8.63 minutes, respectively. It can be seen that the two creators of the former spend less time than the two creators of the latter, confirming that combining computer vision technology with artistic creation of art painting can not only expand the path of art painting materials, but also expand the thinking space of creators and improve creative efficiency. This article hoped that the application of computer vision technology in the creation of art painting can effectively promote the creative inspiration of creators, and explore new ideas for the art of art painting. This article provided a reference for the future development of art painting and artistic creation.
Right-sided infective endocarditis or thrombus? Report of two cases diagnosed by transthoracic echocardiography
Authors: Ge Wenjing , Wu Bijun , Wang Zhen , Zhang Haichun 
Published: May 2023

Abstract
Background
Right-sided infective endocarditis (RSIE) occurs less commonly but is sometimes difficult to diagnose depending on the developing site and causative organism, especially when differentiated from thrombus. There are few reports describing the diagnostic and analytical ideas of tricuspid valve infective endocarditis and pulmonary artery infective endocarditis.
Case presentation
We present two cases of RSIE, one in the tricuspid valve and one in the pulmonary artery, which was misdiagnosed as thrombus by computed tomography angiography.
Conclusions
Vegetation and thrombus can be distinguished according to the nature of the mass, the location of attachment, and the clinical manifestation. Echocardiography enables real-time dynamic observation of the mass, the structural changes of the heart, and cardiac hemodynamic changes caused by various complications and can effectively differentiate vegetation from thrombus.
Perspectives on using ethanol as an internal standard for the quantification of volatile compounds in alcoholic products by headspace SPME–GC/FID without sample preparation
Authors: Korban Anton , Zavoralová Lucie , Čabala Radomír , Egorov Vladimir 
Published: May 2023

Abstract
For the first time, the beneficial "Ethanol as Internal Standard (IS)" method developed for the analysis of alcoholic products was tested in headspace mode of solid-phase microextraction gas chromatography with flame ionization detector (SPME-GC/FID) and compared with the traditional IS method. The extraction and separation conditions were optimized for the analysis of 10 volatile congeners prescribed in European legislation. To evaluate the accuracy of the compared methods, three real alcoholic product samples with ethanol content of 20%, 40%, and 80% v/v were spiked with gravimetrically prepared standard solutions to calculate recoveries. The obtained data indicates that the suggested method can be employed as a robust and accurate tool for SPME analysis of alcoholic products with low ethanol content, such as wines. It was also observed that an increase in ethanol content in the matrix affects the accuracy of the "Ethanol as IS" method, potentially due to non-linearity of analyte extraction. However, in the case of wine sample, the "Ethanol as IS" method showed significantly better results compared to the traditional approach. The precision of the suggested method, evaluated using relative standard deviations (RSD) of obtained concentrations was found to be comparable to that of the traditional method.
Understanding the impact of congenital infections and perinatal viral exposures on the developing brain using white matter magnetic resonance imaging: A scoping review
Authors: Nyakonda Charmaine N , Wedderburn Catherine J , Williams Simone R , Stein Dan J , Donald Kirsten A 
Published: May 2023

AbstractBackground Magnetic Resonance Imaging (MRI)-based imaging techniques are useful to assess white matter (WM) structural and microstructural integrity in the context of infection and inflammation. The purpose of this scoping review was to examine current existing published literature exploring WM neuroimaging approaches to understand the impact of congenital and perinatal viral infections or exposures on the developing brain. Methods This scoping review was conducted according to the Arksey and O’ Malley framework. A literature search was performed in Web of Science, Scopus and PubMed for primary research articles published from database conception up to January 2022. Studies evaluating the use of MRI-based WM imaging techniques in congenital and perinatal viral infections or exposures were included. Results were grouped by age and infection status. Results A total of 826 articles were identified for screening and 28 final articles were included. Congenital and perinatal infections represented in the included studies were cytomegalovirus (CMV) infection, human immunodeficiency virus (HIV) infection and exposure, and herpes simplex virus (HSV) infection. The MRI-based WM imaging methods represented in the included studies were structural MRI and diffusion-weighted and diffusion tensor MRI (DWI/ DTI). The most frequently reported regions with diffusion parameter group differences included the cerebellar region, corticospinal tract and association fibre WM tracts in both children with HIV infection and children who are HIV-exposed uninfected, although there were fewer studies in the latter group. In qualitative imaging studies, WM hyperintensities were the most frequently reported brain abnormality in children with CMV infection and children with HSV infection. Scoping review findings suggested that diffusion parameters have the potential to be specific markers of impairment or damage of WM in viral infections. Conclusion There was evidence to suggest that WM imaging techniques can play a role as diagnostic and evaluation tools, while metrics of quantitative WM imaging modalities have the potential to be specific markers of impairment or damage.
A 3D multi-scale hygro-mechanical model of oak wood
Authors: Livani M. A. , Suiker A. S.J. , Crivellaro A. , Bosco E. 
Published: May 2023

Abstract
A multi-scale framework is proposed for the prediction of the macroscopic hygro-elastic properties of oak wood. The distinctive features of the current multi-scale approach are that: i) four different scales of observation are considered, which enables the inclusion of heterogeneous effects from the nano-, micro-, and meso-scales in the effective constitutive behaviour of oak at the macro-scale, ii) the model relies on three-dimensional material descriptions at each considered length scale, and iii) a moisture-dependent constitutive assumption is adopted at the nano-scale, which allows for recovering the moisture dependency of the material response at higher scales of observation. In the modelling approach, oak wood is considered homogeneous at the macro-scale. The meso-scale description considers the cellular structure of individual growth rings with three different densities. At the micro-scale, the heterogeneous nature of cell walls is described by the characteristics of the primary and secondary cell wall layers. Finally, the nano-scale response is determined by cellulose micro-fibrils embedded in a matrix of hemicellulose and lignin. The oak properties at the four length scales are connected via a three-level homogenization procedure, whereby, depending on the geometry of the fine-scale configuration, an asymptotic homogenization procedure or Voigt averaging procedure is applied at each level to determine the effective hygro-elastic properties at the coarse scale. In addition, the moisture ad-sorption isotherms at each scale are constructed from a volume-weighted averaging of the moisture adsorption characteristics at the scale below. The computational results demonstrate that the moisture-dependent, hygro-elastic behaviour of oak wood is predicted realistically at each considered length scale, thereby revealing the influence of the material density, the micro-fibril orientation, and the hygro-elastic properties at the underlying scales. The computed macro-scale properties of oak are in good agreement with experimental data reported in the literature.
Associations between utilization of dental care and oral health outcomes in the U.S. using the National Health and Nutrition Examination Survey (2017-2020)
Authors: Archer Hannah R. , Li Nicky (Huan) , Kennedy Erinne , Aldosari Muath A. 
Published: May 2023

Abstract
Background
This analysis aims to evaluate the association between the time since and reason for a patient's last dental appointment across clinical oral health outcomes.
Methods
We used data from the 2017–2020 National Health and Nutrition Examination Survey (NHANES), a cross-sectional nationally-representative of US noninstitutionalized adults. The predictors were the time since last dental appointment and the reason for the last dental appointment (routine vs. urgent). We examined the presence and number of missing teeth and teeth with untreated coronal and root caries. Multivariable regression models were used to assess the interaction between time since last dental appointment and reason of the appointment on clinical oral health outcomes.
Results
Two-thirds of the US population had a dental appointment within a year, while 53 million individuals did not visit a dentist for the last three years. The odds of having teeth with untreated coronal or root caries increased with the length of time since the last routine appointment. Compared to those who had a dental appointment within a year, individuals who had their last dental appointment more than 3 years ago had 0.44 times the odds of having missing teeth among routine users (95%CI = 0.33, 0.59) and 0.67 times the odds among urgent users (95%CI = 0.45, 0.98).
Conclusions
Recent routine dental appointments are associated with improved oral health outcomes. Disparities exist in access to care for low-income and/or members of racial/ethnic minorities. The outcomes reiterate how social determinants of health impact access to oral health care and subsequent oral health outcomes.
Instability of deep-sea currents over tidal and seasonal timescales
Authors: Clare Michael , Hunt James , Kane Ian , Miramontes Elda , Fonnesu Marco , Argiolas Ricardo , Malgesini Giuseppe , Wallerand Regis , Bailey Lewis 
Published: May 2023

Abstract

Seafloor currents, including episodic sediment-laden turbidity flows and more sustained thermohaline-driven bottom currents, control the ultimate fate of sediment, carbon and pollutants in the deep-sea. Collectively, these currents form the largest sediment accumulations on Earth, from which past climate records are reconstructed. A long-standing view has been that thermohaline-driven bottom currents are persistent and stable; however, a paucity of direct near-seabed monitoring means this remains untested at field-scale. Here, using the most spatially-extensive and long-duration (4-yrs) monitoring of bottom currents at 34 deep-sea instrumented moorings, we show that such currents are far from steady and continuous. Bottom currents instead show dynamic, spatial variability in velocity and direction over tidal and seasonal timescales, being strongly influenced by local seabed morphology. Prior lower resolution monitoring has underestimated this spatio-temporal variability of bottom currents; hence our results highlight a need for near-bed measurements to more robustly quantify deep-sea sediment, carbon and pollutant fluxes.