bluuebunny/crossref_metadata_2025_split huggingface dataset:
Binuclear Cu complex catalysis enabling Li–CO2 battery with a high discharge voltage above 3.0 V
Authors: Sun Xinyi , Mu Xiaowei , Zheng Wei , Wang Lei , Yang Sixie , Sheng Chuanchao , Pan Hui , Li Wei , Li Cheng-Hui , He Ping , Zhou Haoshen 
Published: February 2023

AbstractLi–CO2batteries possess exceptional advantages in using greenhouse gases to provide electrical energy. However, these batteries following Li2CO3-product route usually deliver low output voltage (<2.5 V) and energy efficiency. Besides, Li2CO3-related parasitic reactions can further degrade battery performance. Herein, we introduce a soluble binuclear copper(I) complex as the liquid catalyst to achieve Li2C2O4products in Li–CO2batteries. The Li–CO2battery using the copper(I) complex exhibits a high electromotive voltage up to 3.38 V, an increased output voltage of 3.04 V, and an enlarged discharge capacity of 5846 mAh g−1. And it shows robust cyclability over 400 cycles with additional help of Ru catalyst. We reveal that the copper(I) complex can easily capture CO2to form a bridged Cu(II)-oxalate adduct. Subsequently reduction of the adduct occurs during discharge. This work innovatively increases the output voltage of Li–CO2batteries to higher than 3.0 V, paving a promising avenue for the design and regulation of CO2conversion reactions.
Single-exonuclease nanocircuits reveal the RNA degradation dynamics of PNPase and demonstrate potential for RNA sequencing
Authors: Yang Zhiheng , Liu Wenzhe , Zhao Lihua , Yin Dongbao , Feng Jianfei , Li Lidong , Guo Xuefeng 
Published: February 2023

AbstractThe degradation process of RNA is decisive in guaranteeing high-fidelity translation of genetic information in living organisms. However, visualizing the single-base degradation process in real time and deciphering the degradation mechanism at the single-enzyme level remain formidable challenges. Here, we present a reliable in-situ single-PNPase-molecule dynamic electrical detector based on silicon nanowire field-effect transistors with ultra-high temporal resolution. These devices are capable of realizing real-time and label-free monitoring of RNA analog degradation with single-base resolution, including RNA analog binding, single-nucleotide hydrolysis, and single-base movement. We discover a binding event of the enzyme (near the active site) with the nucleoside, offering a further understanding of the RNA degradation mechanism. Relying on systematic analyses of independent reads, approximately 80% accuracy in RNA nucleoside sequencing is achieved in a single testing process. This proof-of-concept sets up a Complementary Metal Oxide Semiconductor (CMOS)-compatible playground for the development of high-throughput detection technologies toward mechanistic exploration and single-molecule sequencing.
Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease
Authors: Phelan Jody , Gomez-Gonzalez Paula Josefina , Andreu Nuria , Omae Yosuke , Toyo-Oka Licht , Yanai Hideki , Miyahara Reiko , Nedsuwan Supalert , de Sessions Paola Florez , Campino Susana , Sallah Neneh , Parkhill Julian , Smittipat Nat , Palittapongarnpim Prasit , Mushiroda Taisei , Kubo Michiaki , Tokunaga Katsushi , Mahasirimongkol Surakameth , Hibberd Martin L. , Clark Taane G. 
Published: February 2023

AbstractThe genetics underlying tuberculosis (TB) pathophysiology are poorly understood. Human genome-wide association studies have failed so far to reveal reproducible susceptibility loci, attributed in part to the influence of the underlying Mycobacterium tuberculosis (Mtb) bacterial genotype on the outcome of the infection. Several studies have found associations of human genetic polymorphisms with Mtb phylo-lineages, but studies analysing genome-genome interactions are needed. By implementing a phylogenetic tree-based Mtb-to-human analysis for 714 TB patients from Thailand, we identify eight putative genetic interaction points (P < 5 × 10−8) including human loci DAP and RIMS3, both linked to the IFNγ cytokine and host immune system, as well as FSTL5, previously associated with susceptibility to TB. Many of the corresponding Mtb markers are lineage specific. The genome-to-genome analysis reveals a complex interactome picture, supports host-pathogen adaptation and co-evolution in TB, and has potential applications to large-scale studies across many TB endemic populations matched for host-pathogen genomic diversity.
Zhang-Rice singlets state formed by two-step oxidation for triggering water oxidation under operando conditions
Authors: Peng Chun-Kuo , Lin Yu-Chang , Chiang Chao‐Lung , Qian Zhengxin , Huang Yu-Cheng , Dong Chung-Li , Li Jian‐Feng , Chen Chien-Te , Hu Zhiwei , Chen San-Yuan , Lin Yan-Gu 
Published: February 2023

AbstractThe production of ecologically compatible fuels by electrochemical water splitting is highly desirable for modern industry. The Zhang-Rice singlet is well known for the superconductivity of high-temperature superconductors cuprate, but is rarely known for an electrochemical catalyst. Herein, we observe two steps of surface reconstruction from initial catalytic inactive Cu1+ in hydrogen treated Cu2O to Cu2+ state and further to catalytic active Zhang-Rice singlet state during the oxygen evolution reaction for water splitting. The hydrogen treated Cu2O catalyst exhibits a superior catalytic activity and stability for water splitting and is an efficient rival of other 3d-transition-metal catalysts. Multiple operando spectroscopies indicate that Zhang-Rice singlet is real active species, since it appears only under oxygen evolution reaction condition. This work provides an insight in developing an electrochemical catalyst from catalytically inactive materials and improves understanding of the mechanism of a Cu-based catalyst for water oxidation.
Whole-genome sequencing identifies potential candidate genes for egg production traits in laying ducks (Anas platyrhynchos)
Authors: Sun Yanfa , Zhang Yeqiu , Wu Qiong , Lin Rulong , Chen Hongping , Zhang Min , Lin Jiaqi , Xu Enrong , Li Meng , Cai Yicheng , Deng Fan , Yue Wen , Pan Haozhe , Jiang Xiaobing , Li Yan 
Published: February 2023

AbstractEgg production traits are economically important in laying ducks. Genetic molecular mechanisms and candidate genes underlying these traits remain unclear. In this study, whole genome variants were identified through whole-genome resequencing using three high-egg producing (HEN) and three low-egg producing (LEN) laying ducks. The gene ontology (GO) terms and Kyoto Encyclopedia of Genes and Genome (KEGG) pathways for the genes of common differential variants between HEN and LEN ducks were determined. Frizzled class receptor 6 (FZD6) was further genotyped using the Sequenom MassARRAY iPLEX platform. The association of FZD6 gene polymorphisms with 73 egg production and weight traits in 329 female ducks were estimated. A total of 65,535 single nucleotide polymorphisms (SNPs) and 4,702 indels were identified across the genome. Fourteen GO terms and 14 KEGG pathways were determined for the genes of common differential variants, including MAPK signaling, Wnt signaling, melanogenesis and calcium signaling pathways, which are key functional pathways for poultry egg production reported in previous reports. Further analysis showed that 27 SNPs of FZD6 were associated with three early egg production of duck and egg weight traits, including egg production at 17 weeks (EP17), 18 weeks (EP18) and 19 weeks (EP19) and egg weight at 59 weeks (EW59). The FZD6 should be considered a novel candidate gene for egg production traits in laying ducks.
Data-driven audiogram classifier using data normalization and multi-stage feature selection
Authors: Elkhouly Abeer , Andrew Allan Melvin , Rahim Hasliza A , Abdulaziz Nidhal , Malek Mohd Fareq Abd , Siddique Shafiquzzaman 
Published: February 2023

AbstractAudiograms are used to show the hearing capability of a person at different frequencies. The filter bank in a hearing aid is designed to match the shape of patients’ audiograms. Configuring the hearing aid is done by modifying the designed filters’ gains to match the patient’s audiogram. There are few problems faced in achieving this objective successfully. There is a shortage in the number of audiologists; the filter bank hearing aid designs are complex; and, the hearing aid fitting process is tiring. In this work, a machine learning solution is introduced to classify the audiograms according to the shapes based on unsupervised spectral clustering. The features used to build the ML model are peculiar and describe the audiograms better. Different normalization methods are applied and studied statistically to improve the training data set. The proposed Machine Learning (ML) algorithm outperformed the current existing models, where, the accuracy, precision, recall, specificity, and F-score values are higher. The reason for the better performance is the use of multi-stage feature selection to describe the audiograms precisely. This work introduces a novel ML technique to classify audiograms according to the shape, which, can be integrated to the future and existing studies to change the existing practices in classifying audiograms.
Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation
Authors: Kim Dongkyun , Kim Sohee , Kang Myung-su , Yin Zhinan , Min Booki 
Published: February 2023

AbstractIL-27 is an IL-12 family cytokine with immune regulatory properties, capable of modulating inflammatory responses, including autoimmunity. While extensive studies investigated the major target cells of IL-27 mediating its functions, the source of IL-27 especially during tissue specific autoimmune inflammation has not formally been examined. IL-27p28 subunit, also known as IL-30, was initially discovered as an IL-27-specific subunit, and it has thus been deemed as a surrogate marker to denote IL-27 expression. However, IL-30 can be secreted independently of Ebi3, a subunit that forms bioactive IL-27 with IL-30. Moreover, IL-30 itself may act as a negative regulator antagonizing IL-27. In this study, we exploited various cell type specific IL-30-deficient mouse models and examined the source of IL-30 in a T cell mediated autoimmune neuroinflammation. We found that IL-30 expressed by infiltrating and CNS resident APC subsets, infiltrating myeloid cells and microglia, is central in limiting the inflammation. However, dendritic cell-derived IL-30 was dispensable for the disease development. Unexpectedly, in cell type specific IL-30 deficient mice that develop severe EAE, IL-30 expression in the remaining wild-type APC subsets is disproportionately increased, suggesting that increased endogenous IL-30 production may be involved in the severe pathogenesis. In support, systemic recombinant IL-30 administration exacerbates EAE severity. Our results demonstrate that dysregulated endogenous IL-30 expression may interfere with immune regulatory functions of IL-27, promoting encephalitogenic inflammation in vivo.
Facile fabrication of a novel self-healing and flame-retardant hydrogel/MXene coating for wood
Authors: Zhao Xiaojiong , Tian Min , Wei Ruichao , Jiang Saihua 
Published: February 2023

AbstractTo improve flame retardancy of wood, a novel high-water-retention and self-healing polyvinyl alcohol/phytic acid/MXene hydrogel coating was developed through facile one-pot heating and freeze–thaw cycle methods, and then painted on wood surface. The coating exhibit excellent self-healing property and significantly enhanced water-retention property (water content ≥ 90 wt%), due to the increased hydrogen bonds within the coating system with the presence of MXene nanosheets. Compared to pristine wood, the flame retardancy of coated wood is greatly improved, such as passed V0 rating in UL-94 test, increasing time to ignition (TTI, from 32 to 69 s), and decreased heat release rate and total heat release by 41.6% and 36.14%. The cooling effect and large thermal capacity of high-water-retention hydrogel, and physical barrier effects for flammable gas products, heat and oxygen by MXene nanosheets and the compact char layer formed during combustion play key roles in the flame retardancy enhancements of the wood. High thermal stability of MXene nanosheets is another beneficial factor. The detailed flame-retardant and self-healing mechanisms were proposed.
Monitoring storm evolution using a high-density seismic network
Authors: Diaz J. , Ruiz M. , Udina M. , Polls F. , Martí D. , Bech J. 
Published: February 2023

AbstractData acquired by a dense seismic network deployed in the Cerdanya basin (Eastern Pyrenees) is used to track the temporal and spatial evolution of meteorological events such as rainfall episodes or thunderstorms. Comparing seismic and meteorological data, we show that for frequencies above 40 Hz, the dominant source of seismic noise is rainfall and hence the amplitude of the seismic data can be used as a proxy of rainfall. The interstation distance of 1.5 km provides an unprecedented spatial resolution of the evolution of rainfall episodes along the basin. Two specific episodes, one dominated by stratiform rain and the second one dominated by convective rain, are analyzed in detail, using high resolution disdrometer data from a meteorological site near one of the seismic instruments. Seismic amplitude variations follow a similar evolution to radar reflectivity values, but in some stratiform precipitation cases, it differs from the radar-derived precipitation estimates in this region of abrupt topography, where radar may suffer antenna beam blockage. Hence, we demonstrate the added value of seismic data to complement other sources of information such as rain-gauge or weather radar observations to describe the evolution of ground-level rainfall fields at high spatial and temporal resolution. The seismic power and the rainfall intensity have an exponential relationship and the periods with larger seismic power are coincident. The time intervals with rain drops diameters exceeding 3.5 mm do not result in increased seismic amplitudes, suggesting that there is a threshold value from which seismic data are no longer proportional to the size of the drops. Thunderstorms can be identified by the recording of the sonic waves generated by thunders, with. Single thunders detected to distances of a few tens of kilometers﻿.﻿ As the propagation of these acoustic waves is expected to be strongly affected by parameters as air humidity, temperature variations or wind, the seismic data could provide an excellent tool to investigate atmospheric properties variations during thunderstorms.
Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study
Authors: Takahashi Takuya , Yoshii Toshitaka , Mori Kanji , Kobayashi Shigeto , Inoue Hisashi , Tada Kurisu , Tamura Naoto , Hirai Takashi , Sugimura Nobuhiro , Nagoshi Narihito , Maki Satoshi , Katsumi Keiichi , Koda Masao , Murata Kazuma , Takeuchi Kazuhiro , Nakashima Hiroaki , Imagama Shiro , Kawaguchi Yoshiharu , Yamazaki Masashi , Okawa Atsushi 
Published: February 2023

AbstractTo evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the facet joint and SIJ were evaluated in 111 patients who were diagnosed with DISH and 27 patients with AS on the whole spine CT. The number of anterior bridging and shape of bridging (candle-wax-type/ smooth-type) were also evaluated. We further evaluated patients with DISH and AS by matching their age and sex. Complete SIJ fusion was more common in AS, whereas anterior and posterior bony bridging around SIJ was more common in DISH. However, 63% of patients with DISH had a partial or complete fusion. In spinal anterior bony bridging, the majority of patients with AS had the smooth-type, whereas those with DISH had the candle-wax-type. However, some of the patients with DISH (11%) had smooth-type. Intervertebral facet joint fusion is more common in AS. The number of anterior spinal bony bridging was greater in AS than in DISH, especially in the lumbar spine. These results are useful in differentiating DISH from AS and should therefore be considered when making a diagnosis.
NHANES cross sectional study of aspirin and fractures in the elderly
Authors: Swed Sarya , El-Sakka Amro A. , Abouainain Yasmeen , Lee Ka Yiu , Sawaf Bisher , Albuni Mhd Kutaiba , Battikh Elias , Ahmad Eman Mohammed sharif , Elkalagi Nashaat Kamal Hamdy , Abbas Kirellos Said , Hafez Wael , Rakab Amine 
Published: February 2023

AbstractBone fractures are a global public health concern, yet no thorough investigation of low-dose aspirin usage to prevent fractures in the elderly has been conducted. Many interventional human and animal studies have tried to detect the correct role of low-dose aspirin on fractures in elderly persons. The literature doesn't consist of a retrospective observational study that includes a large number of older individuals and evaluates the accurate effect of aspirin on the fractures post falling from low heights. This cross-sectional includes 7132 elderly persons and aimed to detect if there was a link between taking low-dose aspirin to prevent fractures in the elderly. Data was extracted from the National Health and Nutrition Examination Survey (NHANES) database for 2017–2020 and 2013–2014. Demographic and examination data were collected during in-home interviews and study visits to a mobile examination center. Standardized questionnaires were used to collect information such as age, gender, race, educational level, and family income-to-poverty ratio. Body mass index (BMI), weight, standing height, upper leg length, upper arm length, arm circumference, and wrist circumference were all measured during the examination. The study examined 8127 patients, with 7132 elderly patients suitable for data analysis. The odds ratio of fractures due to a fall from standing height or less was 0.963 (95 percent confidence interval 0.08–1.149) in low-dose aspirin users, while having parents with osteoporosis had a related risk of 1.23. (95 percent confidence interval 0.81–1.8). The total number of fractures was 1295; with hip fractures constituting up to 13.82%, wrist fractures of 66.56%, and spine fractures of 19.61%. There was no significant difference in femur and spine bone mineral density (BMD) in the two groups (use low dose aspirin and don't use). Females had a 5.6 times greater fracture risk related to a fall from standing height or less (1 time or more) than males (P-value < 0.001). Furthermore, taking aspirin had no effect on the occurrence of fractures from standing height or less in older people (P-value = 0.468). In addition, the logistic regression after performing the propensity matching score confirmed that there was no impact of taking aspirin on the occurrence of fractures (P-value > 0.05). This cross-sectional study reveals that taking low-dose aspirin to prevent fractures in the elderly is statistically insignificant. However, fractures are more common in older persons, especially in older women; thus, more widespread injury prevention initiatives and access to osteoporosis prevention and diagnosis for older people should improve to minimize the overall burden.
Ubiquitous spin freezing in the superconducting state of UTe2
Authors: Sundar Shyam , Azari Nasrin , Goeks Mariah R. , Gheidi Shayan , Abedi Mae , Yakovlev Michael , Dunsiger Sarah R. , Wilkinson John M. , Blundell Stephen J. , Metz Tristin E. , Hayes Ian M. , Saha Shanta R. , Lee Sangyun , Woods Andrew J. , Movshovich Roman , Thomas Sean M. , Butch Nicholas P. , Rosa Priscila F. S. , Paglione Johnpierre , Sonier Jeff E. 
Published: February 2023

AbstractIn most superconductors electrons form Cooper pairs in a spin-singlet state mediated by either phonons or by long-range interactions such as spin fluctuations. The superconductor UTe2 is a rare material wherein electrons are believed to form pairs in a unique spin-triplet state with potential topological properties. While spin-triplet pairing may be mediated by ferromagnetic or antiferromagnetic fluctuations, experimentally, the magnetic properties of UTe2 are unclear. By way of muon spin rotation/relaxation (μSR) measurements on independently grown UTe2 single crystals we demonstrate the existence of magnetic clusters that gradually freeze into a disordered spin frozen state at low temperatures. Our findings suggest that inhomogeneous freezing of magnetic clusters is linked to the ubiquitous residual linear term in the temperature dependence of the specific heat (C) and the low-temperature upturn in C/T versus T. The omnipresent magnetic inhomogeneity has potential implications for experiments aimed at establishing the intrinsic low-temperature properties of UTe2.
The Chemistry of Textile Fibres
Authors: Mather Robert R , Wardman Roger H 
Published: February 2023

Textiles are ubiquitous materials that many of us take for granted in our everyday lives. We rely on our clothes to protect us from the environment and use them to enhance our appearance. Textiles also find applications in transport, healthcare, construction, and many other industries.
The revised and updated 2nd Edition of The Chemistry of Textile Fibres highlights the trend towards the synthesis, from renewable resources, of monomers for making synthetic fibres. It contains new information on the influence of legislation and the concerns of environmental organisations on the use of chemicals in the textile industry. New sections on genetically modified cotton, anti-microbial materials and spider silk have been added as well as a new chapter covering functional fibres and fabrics.
This book provides a comprehensive overview of the various types of textile fibres that are available today, ranging from natural fibres to the high-performance fibres that are very technologically advanced. Readers will gain an appreciation of why particular types of fibre are used for certain applications through understanding the chemistry behind their properties.
Students following ‘A’ level courses or equivalent and first-year undergraduate students reading textile technology subjects at university will find this book a valuable source of information.
Green Analytical Chemistry
Authors: Koel Mihkel , Kaljurand Mihkel 
Published: February 2023

Chemical analysis requires solvents, reagents and energy and generates waste. The main goal of green analytical chemistry is to avoid or reduce the undesirable environmental side effects of chemical analysis, while preserving the classic analytical parameters of accuracy, sensitivity, selectivity and precision.
This book portrays the current and changing situation concerning adoption of the principles of green chemistry as applied to analysis. It begins by looking at the advantages of and problems associated with on-site analysis and how analytical techniques can lead to increased productivity, efficiency and accuracy, and thereby reduce the consumption of materials. It then focuses on sample preparation techniques minimising solvent consumption or using alternative solvents, concepts and methods of improving the ‘greenness’ of instrumental analysis where miniaturization is an important part, separation methods from the perspective of green analytical chemistry and chemometrics approaches, which can reduce or can even remove the need for conventional steps in chemical analysis.
Aimed at graduates and novices just entering the field, managers of analytical research laboratories, teachers of analytical chemistry and green public policy makers, this title will be a useful addition to any analytical scientist's library.