bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the economic impacts of severe skeletal anomalies in Mediterranean hatcheries culturing seabream and seabass
Authors: Cantillo Javier , Martín Juan Carlos , Román Concepción 
Published: July 2023

AbstractThe economic impact of skeletal anomalies in aquaculture farming is a significant issue for the industry, as deformed fish are frequently discarded because of their low survival rate and a variety of other disadvantages, including increased costs, consumer distrust of aquaculture products, and ethical concerns. The goal of this article is to propose a method for calculating the direct costs of severe skeletal anomalies in typical Mediterranean seabream and seabass aquaculture hatcheries using a deterministic static model programmed in MATLAB that simulates their annual operation. Our findings suggest that larger hatcheries experience higher direct costs associated with severe skeletal anomalies but have better financial stability and significantly higher expected profits. Mean results indicate that the annual economic losses of severe skeletal anomalies for seabream and seabass Mediterranean aquaculture are 22.88 million euros per year for a scenario of low severe skeletal anomalies, 65.34 million euros per year for a scenario of medium severe skeletal anomalies, and 115.98 million euros per year for a scenario of high severe skeletal anomalies. Furthermore, some options for increasing the financial stability of the hatcheries are to increase the sale price of fingerlings, reduce the feed conversion ratio, and reduce the feed unit cost.
Crustal structure of the Lazufre volcanic complex and the Southern Puna from 3-D inversion of magnetotelluric data: Implications for surface uplift and evidence for melt storage and hydrothermal fluids
Authors: Unsworth Martyn , Comeau Matthew J. , Diaz Daniel , Brasse Heinrich , Heit Benjamin , Favetto Alicia , Pomposiello Cristina , Barcelona Hernan , Peri Giselle , Ticona Faustino 
Published: July 2023

Abstract
The Central Andes are unique in the global system of subduction zones in that a significant, high-altitude plateau has formed above a subduction zone. In this region, both subduction and the associated magmatism have been shown to vary in both space and time. Geophysical data have been invaluable in determining the subsurface structure of this region. Extensive seismic studies have determined the regional-scale distribution of partial melt in the crust and upper mantle. Magnetotelluric studies have been effective in providing independent constraints on the quantity and composition of partial melt in the crust and upper mantle. Geodetic studies have shown that a small number of volcanic centers exhibit persistent, long-term uplift that may indicate the formation of plutons or future eruptions.
This paper describes a detailed study of the Southern Puna using magnetotelluric (MT) data. This region is located at the southern limit of the Central Andes in a region where a recent transition from flat-slab subduction to normal subduction has caused an increase in magmatism, in addition to hypothesized lithospheric delamination. It is also a region where an extensive zone adjacent to the volcanic arc is undergoing surface uplift, located near Volcán Lastarria and Cordon del Azufre (collectively called Lazufre). The main goals of the work are to define the crustal structure and to investigate processes that may cause surface uplift of relatively large regions not associated with active volcanism.
As part of the PLUTONS project, MT data were collected on an east-west transect (approximately along 25°S) that extended across the Southern Puna, from Lazufre to north of Cerro Galan. The data were combined with previously collected MT data around Lazufre and inverted to give a 3-D resistivity model of the crust. The low resistivity of the crust resulted in limited sensitivity to mantle structure. A number of major crustal conductors were detected and included (1) a mid-crustal conductor extending eastward from the volcanic arc as far as the Salar de Antofalla; (2) an upper- to mid-crustal conductor located north of Cerro Galan; and (3) a conductor that rises westward from (1) and terminates directly beneath the region of surface uplift at Lazufre. These conductors are broadly coincident with the location of crustal low shear-wave anomalies. The conductive features were interpreted to be due to zones of partial melt stored in the crust, and petrological data were used to estimate melt fractions. Below Lazufre, it is likely that aqueous fluids contribute to the high conductivity, which is observed within the depth range of the inflation source, giving evidence that the surface uplift may be associated with both magmatic and hydrothermal processes.
MAω1(S)[S] does not imply 𝒦2
Authors: Peng Yinhe , Wu Liuzhen 
Published: July 2023

We construct a model in which MA[Formula: see text] holds and [Formula: see text] fails. This shows that MA[Formula: see text] does not imply [Formula: see text] and answers an old question of Larson and Todorcevic in [Katetov’s problem, Trans. Amer. Math. Soc. 354(5) (2002) 1783–1791]. We also investigate different strong colorings in models of MA[Formula: see text].
Functional equations for the stochastic exponential
Authors: Chikvinidze Besik , Mania Michael , Tevzadze Revaz 
Published: July 2023

In this paper, we consider two versions of functional equations for the stochastic exponential. One equation for a function of a semimartingale and its square characteristic and the second for non-anticipative functionals. A martingale characterization of the general solutions of these equations is given.
Primary Prevention and Interception Studies in RAS-Mutated Tumor Models Employing Small Molecules or Vaccines
Authors: Dragnev Konstantin H. , Lubet Ronald A. , Miller Mark Steven , Sei Shizuko , Fox Jennifer T. , You Ming 
Published: July 2023

Abstract
Therapeutic targeting of RAS-mutated cancers is difficult, whereas prevention or interception (treatment before or in the presence of preinvasive lesions) preclinically has proven easier. In the A/J mouse lung model, where different carcinogens induce tumors with different KRAS mutations, glucocorticoids and retinoid X receptor (RXR) agonists are effective agents in prevention and interception studies, irrespective of specific KRAS mutations. In rat azoxymethane-induced colon tumors (45% KRAS mutations), cyclooxygenase 1/2 inhibitors and difluoromethylornithine are effective in preventing or intercepting KRAS-mutated or wild-type tumors. In two KRAS-mutant pancreatic models multiple COX 1/2 inhibitors are effective. Furthermore, combining a COX and an EGFR inhibitor prevented the development of virtually all pancreatic tumors in transgenic mice. In the N-nitroso-N-methylurea-induced estrogen receptor–positive rat breast model (50% HRAS mutations) various selective estrogen receptor modulators, aromatase inhibitors, EGFR inhibitors, and RXR agonists are profoundly effective in prevention and interception of tumors with wild-type or mutant HRAS, while the farnesyltransferase inhibitor tipifarnib preferentially inhibits HRAS-mutant breast tumors. Thus, many agents not known to specifically inhibit the RAS pathway, are effective in an organ specific manner in preventing or intercepting RAS-mutated tumors. Finally, we discuss an alternative prevention and interception approach, employing vaccines to target KRAS.
Barriers to digital government and the COVID-19 crisis – A comparative study of federal government entities in the United States and Austria
Authors: Moser-Plautz Birgit 
Published: July 2023

Digital government has been an evolving topic in research and practice, and during the COVID-19 crisis, different tools emerged as crucial elements in tackling the crisis. Comparing the federal level in the United States (Anglo-Saxon public interest culture) and in Austria (continental European rule-of-law culture), this article looks at how different barriers to digital government were affected by the COVID-19 crisis. Fourteen semi-structured interviews with experts in United States departments and their Austrian counterparts are conducted. The results show strong similarities between the United States and Austria in cultural barriers (bureaucratic culture, resistance to change, risk aversion) but also in structural barriers (political commitment and resources, workforce) to digital government. The main difference lies in laws and regulations as structural barriers, stemming from the different administrative traditions. Furthermore, the study highlights the dynamic nature of barriers. It shows that a crisis can result in the lowering of both structural as well as cultural barriers. Deliberate removal of structural barriers in experimentation spaces may therefore enhance digital government in ‘orderly’ times as well. Points for practitioners Knowing how to overcome certain barriers is essential in innovation processes. This study shows that windows of opportunity can be opened by a crisis, but also provides key learnings for policy measures that can be taken in ‘orderly’ times. Public administrations require space where structural barriers are deliberately removed in order to experiment and learn, which can lower cultural barriers to digital government as well.
Enhancement of Tendon-to-Bone Healing: Choose a Monophasic or Hierarchical Scaffold?
Authors: Zhang Xuancheng , Han Kang , Fang Zhaoyi , Cho Eunshinae , Huangfu Xiaoqiao , Zhao Jinzhong 
Published: July 2023

Background: To enhance the healing of tendon to bone, various biomimetically hierarchical scaffolds have been proposed. However, the fabrication of such scaffolds is complicated. Furthermore, the most significant result after a routine repair is loss of the transition zone between the tendon and bone, whose main components are similar to fibrocartilage. Purpose: To compare tendon-to-bone healing results in a rabbit model using a monophasic graft (decellularized fibrocartilage graft; DFCG) and hierarchical graft (decellularized tendon-to-bone complex; DTBC) that contain the native hierarchical enthesis. Study Design: Controlled laboratory study. Methods: DFCG and DTBC were harvested from allogenic rabbits. A rabbit model of a chronic rotator cuff tear was established, and 3 groups were assessed: direct repair or repair with DFCG or DTBC fixed between the tendon and bone. Hierarchical evaluations of the repaired tendon-to-bone interface were performed with regard to the tendon zone, transition zone, and bone zone using histological staining and micro–computed tomography scanning. Biomechanical analysis was performed to evaluate the general healing strength. Results: The healing results in the tendon zone exhibited no significant difference among the 3 groups at any time point. In the transition zone, the grade in the direct repair group was significantly lower than that in the DFCG and DTBC groups at 4 weeks, and the grade in the DFCG group was significantly lower than that in the DTBC group at this time point. However, any significant difference between the DFCG group and DTBC group could no longer be detected at 8 and 16 weeks, which was inconsistent with the results of the biomechanical analysis. Micro–computed tomography analysis showed no significant difference among the 3 groups with regard to bone mineral density at 16 weeks. Conclusion: A monophasic DFCG was able to achieve enhanced tendon-to-bone healing similar to that with hierarchical DTBC over the long term, with regard to both histological and biomechanical properties. Clinical Relevance: Fabrication of a monophasic scaffold instead of a hierarchical scaffold to promote regeneration and remodeling of a transition zone, which was mainly composed of fibrocartilaginous matrix between the tendon and bone, may be sufficient to enhance tendon-to-bone healing.
Effects of Senility on Disease Burden: Panel Analysis Using 2010 to 2019 OECD Health Data
Authors: Kim Heesun , Kim Eun-Jung 
Published: July 2023

Background: In this study, the geniatric status of OECD (Organisation for Economic Co-operation and Development) countries was measured, and the effects of aging status on disease patterns in each country were quantitatively assessed. A theoretical model explaining the effects was suggested, and the implications were discussed. Methods: Data used in this study were the OECD Health Statistics data and WHO Global Burden of Disease data. The values for each country were paired with disability-adjusted life years (DALYs) presented by the WHO and Institute for Health Metrics and Evaluation (IHME). A cross-country panel analysis was conducted to analyze the effects of senility on the burden of disease in OECD countries. Results: Geniatric status had effects on the burden of disease ( P = .048). Total health expenditure significantly reduced the burden of disease ( P = .001). In the panel model with YLL (Year of Life Lost) as the outcome variable, geniatric status had twice greater effects on the burden of disease than that in the model with DALY ( P = .003). Conclusions: In medical insurance-related policies, the characteristics of the disease should be considered. In particular, chronic diseases have not received much attention compared to their risk. However, the disease that actually affects the burden of disease is a disease that becomes chronic and requires long-term treatment rather than a disease with a high fatality rate. And, as a result of this study, the higher the level of resource consumption for treatment in OECD countries, where aging is progressing, the burden of disease was rather reduced. Therefore, if there is institutional support to receive appropriate treatment, it will be possible to reduce the national burden of disease.
Development of a model for the optimization of the main factors influencing a 162kW wheeled tractor driver’s whole body vibration
Authors: Sun Liming , Shang Tansu , Chen Hongtao , Wang Zhipeng , Wang Chuqiao , Luo Fuqiang 
Published: July 2023

The vibration tests were carried out using a 162kW wheeled tractor to evaluate the Whole-body vibration while the tractor working in the field, driving on concrete road and in-parking state. The tractor ride comfort was analyzed using the joint weighted acceleration of seat surface vibration from 1 to 80 Hz as the evaluation indicator, according to ISO2631 standard suggestions. During field work, the combined acceleration of the driver’s whole body vibration is 1.39, and the subjective feeling is extremely uncomfortable. Based on the multi-body dynamics analysis software, a tractor dynamics simulation model including the seat, cab mounts, chassis, tyre and road coupling system was established. By changing the model parameters, the influence of the tractor driver’s whole body vibration under the condition of the artificial test track was further analyzed. The analysis shows that the factors that have a greater impact on the driver’s whole body vibration when driving on the artificial runway are the vertical stiffness of the tyre, the vertical stiffness of the seat suspension, and the damping coefficient of the tyre.
Developing a Healthy Lifestyle Program for Recent Kidney Transplant Recipients
Authors: Gibson Cheryl A. , Gupta Aditi , Naik Abhijit , Sullivan Debra K. , Doshi Mona , Backes Jim , Harvey Susan , Lee Jaehoon , Mount Rebecca , Valentine Heather , Shaffer Kelly 
Published: July 2023

Introduction Many kidney transplant recipients experience weight gain in the first year after transplantation. Research Question The objective of this research study was to assess the desires of recent kidney transplant patients about the design features of a healthy lifestyle program to counter unnecessary weight gain. Design In this descriptive study, recent recipients at 2 transplant centers were invited to participate in an online survey. Survey items included sociodemographic information, current medications, health conditions, weight change posttransplant, diet behaviors, physical activity participation, and desired features of a lifestyle program. Results Fifty-three participants, mean age 60.5 (11.2) years, primarily males, completed surveys. Forty percent gained weight posttransplantation with many indicating struggling with their diet. Physical activity levels stayed the same (17%) or decreased (40%) posttransplantation. Eighty-seven percent of participants indicated they would participate in an online lifestyle program and 76% wanted online physical activity and nutrition sessions to meet at least once weekly. Suggestions about the type of information and activities, included eating strategies (eg, how to eat healthfully at restaurants, grocery shopping tips, and recipes), resources for at-home physical activities, access to cooking classes, and apps to track both activity and food intake. Conclusion Recent kidney transplant recipients would benefit from and desired to join a lifestyle program featuring tailored nutrition education and physical activity coaching. Gathered information will be used to inform and tailor a lifestyle program. Identifying features for the prevention of unnecessary weight gain with patients’ input is essential for promoting and sustaining healthy behaviors.
The Associations between Helicobacter Pylori immunoglobulin G seropositivity and body mass index in adults
Authors: Huang Jinke , Zhang Kunli , Wang Fengyun , Tang Xudong 
Published: July 2023

Abstract
Objectives
Inconsistent evidence currently exists regarding the associations between Helicobacter Pylori (H. pylori) infection and body mass index (BMI). The goal of the current study was to examine independent associations of H. pylori immunoglobulin G (IgG) seropositivity and BMI in a U.S.-based population sample.

Methods
The US National Health and Nutrition Examination Survey (NHANES) with 2,576 subjects from 1999 to 2000 were analyzed. Using multivariate logistic regression models, associations between H. pylori IgG seropositivity and BMI were calculated after potential confounders were taken into account. Subgroup analyses were conducted furtherly stratified by sex, age, and race.

Results
H. pylori IgG seropositivity was not associated with BMI in the general population (OR = 0.998; 95% CI = 0.977–1.019; P = 0.842). In the subgroup analyses stratified by race, a negative correction was found between the H. pylori IgG seropositivity and BMI among other races (OR = 0.873; 95% CI = 0.795–0.959; P = 0.004) except non-Hispanic white (OR = 1.006, 95% CI 0.966 to 1.048, P = 0.762), non-Hispanic black (OR = 1.021, 95% CI 0.979 to 1.065, P = 0.335), and Mexican American (OR = 1.010, 95% CI 0.966 to 1.055, P = 0.665).

Conclusions
In the general population, H. pylori IgG seropositivity is not associated with increased BMI, which provides a new perspective on obesity management.
“Danmu” preference, problematic online video watching, loneliness and personality: An eye-tracking study and survey study
Authors: Yan Zhihao , Yang Zeyang , Griffiths Mark D. 
Published: July 2023

Abstract‘Danmu’ (i.e., comments that scroll across online videos), has become popular on several Asian online video platforms. Two studies were conducted to investigate the relationships between Danmu preference, problematic online video watching, loneliness and personality. Study 1 collected self-report data on the study variables from 316 participants. Study 2 collected eye-tracking data of Danmu fixation (duration, count, and the percentages) from 87 participants who watched videos. Results show that fixation on Danmu was significantly correlated with problematic online video watching, loneliness, and neuroticism. Self-reported Danmu preference was positively associated with extraversion, openness, problematic online video watching, and loneliness. The studies indicate the potential negative effects of Danmu preference (e.g., problematic watching and loneliness) during online video watching. The study is one of the first empirical investigations of Danmu and problematic online video watching using eye-tracking software. Online video platforms could consider adding more responsible use messaging relating to Danmu in videos. Such messages may help users to develop healthier online video watching habits.
Cost and affordability of a healthy diet for urban populations in Thailand and the Philippines before and during the COVID-19 pandemic
Authors: Mwambi Mercy , Schreinemachers Pepijn , Praneetvatakul Suwanna , Harris Jody 
Published: July 2023

Abstract
Background
The coronavirus disease 2019 (COVID-19) pandemic severely affected global food security, but analyses of its impact on the cost and affordability of a healthy diet are limited. This study examines the immediate effect of the COVID-19 pandemic on the cost and affordability of a healthy diet among urban households in Bangkok, Thailand and Manila, the Philippines.

Methods
We used official food price and household income and food expenditure data from the national statistics offices. The cost of recommended diet (CoRD) method was employed to assess the minimum cost of a healthy diet, following the healthy diet recommendations provided in the national food-based dietary guidelines of the specific countries. Regression discontinuity design was estimated to determine the COVID-19 effect on food prices and scenario analysis done to determine the effect of reduced food budgets with and without government relief programs.

Results
The results show that the average cost of the recommended diet was US$ 1.55 per person/day in Bangkok and US$ 3.76 in Manila (2019 prices in purchasing power parities) immediately before the pandemic. This diet is generally affordable for all households in Bangkok, but only for 37% of households (4.98 million people) in Manila, indicating much higher poverty in the latter. The pandemic and associated government measures decreased the cost of the recommended diet with 6.5% in Bangkok (p = 0.001) but not in Manila (p = 0.167). Assuming contractions in people’s food budgets of 15–20%, the recommended diet became unaffordable for 0.08–0.12 million people in Bangkok and 6.32–7.73 million people in Manila during the pandemic. Government relief largely compensated for this loss in Bangkok, but relief payments in Manila were not enough to compensate the effect.

Conclusion
These results show that the main effect of the COVID-19 pandemic on the affordability of healthy diets was through the effect on reduced incomes of the poor rather than through prices. Government relief measures should target low-income households to give them the means to purchase healthy food items.
Diagnostic value of cervical vertebral maturation stages for midpalatal suture maturation assessment: a study in the Chinese population
Authors: Liu Henglang , Feng Linjing , Wang Lili 
Published: July 2023

Abstract
Purpose
To evaluate the correlation between cervical vertebral maturation stages (CVMS) and midpalatal suture maturation stages (MPSMS), and to analyze the diagnostic value of CVMS for the assessment of MPSMS.

Methods
Cone beam computed tomography (CBCT) images of 233 subjects (8–20 years) were selected. The CVMS was determined using the McNamara and Franchi method, while the MPSMS was evaluated using the Angelieri method. Spearman rank correlation was used to analyze the results, and positive likelihood ratios were calculated to evaluate the diagnostic value of CVMS in identifying MPSMS.

Results
Spearman rank correlation results showed a strong positive correlation (r = 0.867, P < 0.001) between CVMS and MPSMS. The positive likelihood ratios of CS12, CS4, and CS56 for the identification of stages AB, C, and DE were 12.17, 7.64, and 7.79, respectively. The values of the positive likelihood ratios of the other groups were less than five.

Conclusion
CS12 of the CVMS can be used as a reliable indicator for the assessment of MPSMS stage AB. From CVMS stage 4 forward, midpalatal suture maturation should be evaluated using CBCT.