bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, attitudes, and practices towards seasonal influenza vaccination among pregnant women and healthcare workers: A cross‐sectional survey in Afghanistan
Authors: Shahid Shahira , Kalhoro Shafi , Khwaja Hajra , Hussainyar Mohammad Asif , Mehmood Junaid , Qazi Muhammad Farrukh , Abubakar Abdinasir , Mohamed Shaza , Khan Wasiq , Jehan Fyezah , Nisar Muhammad Imran 
Published: March 2023

AbstractBackgroundDespite recommendation by the World Health Organization (WHO), influenza vaccination coverage among high‐risk groups remains suboptimal in Afghanistan. This study aims to document the knowledge, attitudes, and practices of seasonal influenza vaccine uptake among two priority groups, pregnant women (PWs) and healthcare workers (HCWs).MethodsThis cross‐sectional study enrolled PWs and HCWs in Kabul, Afghanistan, from September to December 2021. Data on vaccine intention and uptake, knowledge, and attitudes towards vaccination were collected. Simple linear regression was used to predict the impact of sociodemographic characteristics on the KAP score.ResultsA total of 420 PWs were enrolled in Afghanistan. The majority (89%) of these women had never heard of the influenza vaccine but 76% intended to receive the vaccine. Of the 220 HCWs enrolled, 88% were unvaccinated. Accessibility and cost were factors which encouraged vaccination among HCWs. Fear of side effects and affordability were identified as key barriers. HCWs reported high level of vaccine intention (93%). PWs aged under 18 years (β: 6.5, P = 0.004), between 18 and 24 years (β: 2.9, P = 0.014), currently employed (β: 5.8, P = 0.004), and vaccinated against COVID‐19 (β: 2.8, P = 0.01) were likely to have a higher attitude score. Among HCWs, being female was a predictor for poor vaccination practice (β: −1.33, P < 0.001) whereas being vaccinated against COVID‐19 was a predictor for higher practice score (β: 2.4, P < 0.001).ConclusionTo increase influenza vaccination coverage among priority groups, efforts should be made to address issues such as lack of knowledge, limited availability, and cost barriers.
Synthesis of passively prelithiated SiOx nanoparticles for Li‐ion battery anode
Authors: Kim Nakwon , Lee Wooyoung , Kim Joonsoo , Kim Daeil , Jang Boyun 
Published: March 2023

AbstractA new concept of passive prelithiation to SiOx nanoparticles is introduced and evaluated by investigating their nanostructures and electrochemical properties. Specifically, Li is incorporated into SiOx nanoparticles during the nanoparticle synthesis. We obtain Si‐Li‐O‐based nanoparticles, which we call SILIO; these are much larger than SiOx particles and have totally different nanostructures. Due to nanostructures with various phase distributions, SILIO nanoparticles show enhanced electrochemical properties. The initial reversible capacity (IRC) and initial columbic efficiency (ICE) of SILIO nanoparticles are 946 to 1107 mAh/g and 72% to 77%, respectively, while SiOx exhibits 1,064 mAh/g of IRC only with 41.5% of ICE. In addition, the stability of SILIO in the air is evaluated to guarantee no unstable phases such as Li2Ox (x = 0–2) are present in SILIO. Through our findings, we suggest a new nanostructure model composed of crystalline Si, amorphous SiOx, and lithium silicate.
Potential impact of ADAM‐10 genetic variants with the clinical features of oral squamous cell carcinoma
Authors: Chen Yi‐Tzu , Lin Chiao‐Wen , Chou Ying‐Erh , Su Shih‐Chi , Chang Lun‐Ching , Lee Chia‐Yi , Hsieh Ming‐Ju , Yang Shun‐Fa 
Published: March 2023

AbstractA disintegrin and metalloproteinase domain‐containing protein 10 (ADAM‐10) involves in the tumour progression, but the impacts of single‐nucleotide polymorphism (SNP) of ADAM‐10 on oral squamous cell carcinoma (OSCC) remain unclear. The aim of this study was to investigate the influence of SNP of ADAM‐10 on the clinical features of OSCC in male Taiwanese. Five loci of ADAM‐10 SNPs including rs653765 (C/T), rs2305421 (A/G), rs514049 (A/C), rs383902 (T/C) and rs2054096 (A/T) were genotyped by TaqMan allelic discrimination in 1138 OSCC patients and 1199 non‐OSCC individuals. The ADAM‐10 SNP rs2305421 GG (AOR: 1.399, 95% CI: 1.045–1.874, p = 0.024) and G allele (AOR: 1.170, 95% CI: 1.012–1.351, p = 0.034) illustrated a significantly higher genotypic frequencies in the OSCC group compared to the distribution of the ADAM‐10 SNP rs2305421 AA wild type. In the subgroup analysis, the ADAM‐10 SNP rs383902 TC+CC was significantly correlated to tumour size larger than T2 in betel quid chewer (AOR: 1.375, 95% CI: 1.010–1.872, p = 0.043), while the ADAM‐10 SNP rs653765 CT+TT was significantly associated with tumour size larger than T2 in cigarette smoker (AOR: 1.346, 95% CI: 1.023–1.772, p = 0.034). The results from The Cancer Genome Atlas revealed highest ADAM‐10 mRNA level in T2 stage of current smokers with head and neck squamous cell carcinoma (HNSCC). In conclusions, the ADAM‐10 SNP rs2305421 G allele is associated with the presence of OSCC, and the ADAM‐10 SNP rs383902 TC+CC and ADAM‐10 SNP rs653765 CT+TT correlates to large tumour size in specific conditions.
Breastfeeding duration is associated with larger cortical gray matter volumes in children from the ABCD study
Authors: Núñez Christian , García‐Alix Alfredo , Arca Gemma , Agut Thais , Carreras Nuria , Portella Maria J. , Stephan‐Otto Christian 
Published: March 2023

BackgroundDespite the numerous studies in favor of breastfeeding for its benefits in cognition and mental health, the long‐term effects of breastfeeding on brain structure are still largely unknown. Our main objective was to study the relationship between breastfeeding duration and cerebral gray matter volumes. We also explored the potential mediatory role of brain volumes on behavior.MethodsWe analyzed 7,860 magnetic resonance images of children 9–11 years of age from the Adolescent Brain Cognitive Development (ABCD) dataset in order to study the relationship between breastfeeding duration and cerebral gray matter volumes. We also obtained several behavioral data (cognition, behavioral problems, prodromal psychotic experiences, prosociality, impulsivity) to explore the potential mediatory role of brain volumes on behavior.ResultsIn the 7,860 children analyzed (median age = 9 years and 11 months; 49.9% female), whole‐brain voxel‐based morphometry analyses revealed an association mainly between breastfeeding duration and larger bilateral volumes of the pars orbitalis and the lateral orbitofrontal cortex. In particular, the association with the left pars orbitalis and the left lateral orbitofrontal cortex proved to be very robust to the addition of potentially confounding covariates, random selection of siblings, and splitting the sample in two. The volume of the left pars orbitalis and the left lateral orbitofrontal cortex appeared to mediate the relationship between breastfeeding duration and the negative urgency dimension of the UPPS‐P Impulsive Behavior Scale. Global gray matter volumes were also significant mediators for behavioral problems as measured with the Child Behavior Checklist.ConclusionsOur findings suggest that breastfeeding is a relevant factor in the proper development of the brain, particularly for the pars orbitalis and lateral orbitofrontal cortex regions. This, in turn, may impact impulsive personality and mental health in early puberty.
Sex‐specific paternal age effects on offspring quality in Drosophila melanogaster
Authors: Aguilar Prem , Dag Berfin , Carazo Pau , Sultanova Zahida 
Published: March 2023

AbstractAdvanced paternal age has been repeatedly shown to modulate offspring quality via male‐ and/or female‐driven processes, and there are theoretical reasons to expect that some of these effects can be sex‐specific. For example, sex allocation theory predicts that, when mated with low‐condition males, mothers should invest more in their daughters compared to their sons. This is because male fitness is generally more condition‐dependent and more variable than female fitness, which makes it less risky to invest in female offspring. Here, we explore whether paternal age can affect the quality and quantity of offspring in a sex‐specific way using Drosophila melanogaster as a model organism. In order to understand the contribution of male‐driven processes on paternal age effects, we also measured the seminal vesicle size of young and older males and explored its relationship with reproductive success and offspring quality. Older males had lower competitive reproductive success, as expected, but there was no difference between the offspring sex ratio of young and older males. However, we found that paternal age caused an increase in offspring quality (i.e., offspring weight), and that this increase was more marked in daughters than sons. We discuss different male‐ and female‐driven processes that may explain such sex‐specific paternal age effects.
Consequences of adaptation to larval crowding on sexual and fecundity selection in Drosophila melanogaster
Authors: Narasimhan Aaditya ,   Jigisha, Kapila Rohit , Meena Abhishek ,   Santhosh, Prasad Nagaraj Guru 
Published: March 2023

AbstractSexual selection is a major force influencing the evolution of sexually reproducing species. Environmental factors such as larval density can manipulate adult condition and influence the direction and strength of sexual selection. While most studies on the influence of larval crowding on sexual selection are either correlational or single‐generation manipulations, it is unclear how evolution under chronic larval crowding affects sexual selection. To answer this, we measured the strength of sexual selection on male and female Drosophila melanogaster that had evolved under chronic larval crowding for over 250 generations in the laboratory, along with their controls which had never experienced crowding, in a common garden high‐density environment. We measured selection coefficients on male mating success and sex‐specific reproductive success, as separate estimates allowed dissection of sex‐specific effects. We show that experimental evolution under chronic larval crowding decreases the strength of sexual and fecundity selection in males but not in females, relative to populations experiencing crowding for the first time. The effect of larval crowding in reducing reproductive success is almost twice in females than in males. Our study highlights the importance of studying how evolution in a novel, stressful environment can shape adult fitness in organisms.
Maxillary midline diastema closure with sectional feldspathic porcelain veneers: A case series followed 1 to 4 years
Authors: Chen Cui‐Ting , Yang Bin , Yin Ya‐Xiong , Wang Xiao‐Dong , Zhao Ke 
Published: March 2023

AbstractObjectiveTo evaluate clinical outcome of maxillary midline diastema closure using sectional feldspathic porcelain veneers up to 4 years.Materials and MethodsFive female patients with stable maxillary midline diastema were included in the current study and restored with minimal invasive sectional feldspathic porcelain veneers under dental microscope. Esthetic, functional, as well as biologic properties of sectional veneers were evaluated according to the World Dental Federation (FDI) criteria after 1 to 4 years' follow‐up.ResultsBased on FDI criteria, all five cases were evaluated as clinically excellent to satisfactory during a mean observation period of 26.4 months. Slight to moderate cervical marginal staining was observed in two cases after 3 to 4 years' follow‐up. Slight white line or ditching of labial surface margin was found in most cases, but it is not easy to be noticed with saliva covering the margins.ConclusionsSectional feldspathic porcelain veneers presented satisfying clinical outcome with potential long‐term esthetic risk for maxillary midline diastema closure.Clinical Significance1. Sectional feldspathic porcelain veneers presented satisfying short to medium term clinical performance when applied to close maxillary midline diastema.2. The exposure of labial surface margin may increase a long‐term potential esthetic risk.
Impact of cross‐sectional orientation in one‐dimensional hydrodynamic modeling on flood inundation mapping
Authors: Jesna Ismail , Bhallamudi S. M. , Sudheer K. P. 
Published: March 2023

AbstractFlood management activities require development of flood maps that depict the spatial and temporal extent of floods with the help of hydrodynamic models. Two‐dimensional (2‐D) hydrodynamic models are frequently employed for flood inundation modeling and mapping with the help of high‐end computational resources and high‐resolution terrain information such as LiDAR (light detection and ranging) data. However, LiDAR data are either unavailable or not freely accessible in many parts of the world, especially in nations belonging to Global South. Hence, one‐dimensional (1‐D) models are still in practice owing to their lesser computational cost and data requirement. Nonetheless, the successful application of a 1‐D model depends mainly on the representation of the natural river and floodplain geometry, which is the primary input in the form of discrete cross‐sections. The assumed flow directions on floodplains while orienting the cross‐sections in 1‐D models induce some uncertainty in the model simulations. This study aims to evaluate the variability in the model simulations caused by the cross‐sectional orientations. Flood simulations were performed using a 1‐D hydrodynamic model for six different cross‐sectional realizations for three river reaches, having distinct morphological and topographical characteristics, and were compared with the simulations of a 2‐D hydrodynamic model and available reference inundation maps. The study suggests that the simulations of flood inundation extent and maximum flow depth variation are influenced by the cross‐sectional orientation on flood plains in river reaches characterized by broad flood plains with complex local topographical variations. In contrast, for reaches with relatively less wide and complex terrains, 1‐D models can generate robust simulations of flood inundation extent and spatial variation in maximum flood depth (R2 and NSE greater than 0.89) for high flood events.
Healthcare professionals' perspectives on dietary advice provided to people with an ileostomy
Authors: Mitchell Alexandra , Herbert Georgia , England Clare , Atkinson Charlotte , Searle Aidan 
Published: March 2023

AbstractBackgroundDiet is a common concern among people with an ileostomy as it can be associated with serious and burdensome complications, for example, dehydration and obstruction, and dietary advice is often unsatisfactory. In this study, we explored healthcare professionals' (HCPs) perspectives on dietary advice for ileostomy management.MethodsSemi‐structured interviews were conducted with HCPs, from multiple professions, who provide dietary advice to patients with an ileostomy. A framework approach to thematic analysis was used to understand and compare HCPs' experiences, beliefs and attitudes that influence how dietary advice is provided and the effectiveness of dietary management.ResultsFindings from interviews with 21 HCPs, across 3 hospitals, related to 7 key themes: tailoring of dietary advice to the patient, patient autonomy and communication, HCP knowledge and understanding, patient pathway, mixed messages, access to formal and social support and patient understanding and relationship with dietary advice. Profession was a strong determinator of what and how dietary advice is provided; however, closer team working increased consistency in dietary advice. Lack of scientific research and consensus contributes to mixed messages and reduced confidence in dietary advice for people with an ileostomy. Due to individual differences between patients, experiential learning with diet is key to self‐management and is encouraged in a controlled way by HCPs; however, a lack of ‘one‐size‐fits‐all’ guidance can be difficult for some.ConclusionThe study findings should inform HCPs caring for patients with an ileostomy, and researchers designing and evaluating interventions, to improve how patients receive dietary advice for ileostomy management.
The transcriptional regulator JAZ8 interacts with the C2 protein from geminiviruses and limits the geminiviral infection in Arabidopsis
Authors: Rosas‐Diaz Tabata , Cana‐Quijada Pepe , Wu Mengshi , Hui Du , Fernandez‐Barbero Gemma , Macho Alberto P. , Solano Roberto , Castillo Araceli G. , Wang Xiao‐Wei , Lozano‐Duran Rosa , Bejarano Eduardo R. 
Published: March 2023

ABSTRACTJasmonates (JAs) are phytohormones that finely regulate critical biological processes, including plant development and defense. JASMONATE ZIM‐DOMAIN (JAZ) proteins are crucial transcriptional regulators that keep JA‐responsive genes in a repressed state. In the presence of JA‐Ile, JAZ repressors are ubiquitinated and targeted for degradation by the ubiquitin/proteasome system, allowing the activation of downstream transcription factors and, consequently, the induction of JA‐responsive genes. A growing body of evidence has shown that JA signaling is crucial in defending against plant viruses and their insect vectors. Here, we describe the interaction of C2 proteins from two tomato‐infecting geminiviruses from the genus Begomovirus, tomato yellow leaf curl virus (TYLCV) and tomato yellow curl Sardinia virus (TYLCSaV), with the transcriptional repressor JAZ8 from Arabidopsis thaliana and its closest orthologue in tomato, SlJAZ9. Both JAZ and C2 proteins colocalize in the nucleus, forming discrete nuclear speckles. Overexpression of JAZ8 did not lead to altered responses to TYLCV infection in Arabidopsis; however, knock‐down of JAZ8 favors geminiviral infection. Low levels of JAZ8 likely affect the viral infection specifically, since JAZ8‐silenced plants neither display obvious developmental phenotypes nor present differences in their interaction with the viral insect vector. In summary, our results show that the geminivirus‐encoded C2 interacts with JAZ8 in the nucleus, and suggest that this plant protein exerts an anti‐geminiviral effect.
Traditional Chinese medicine–based integrated health interventions for depression: A systematic review and meta‐analysis
Authors: Ruan Jiayin , Chen Shucheng , Liang Jiagui , Ho Fiona Yan Yee , Cheung Teris , Ho Janice Yuen Shan , Chan Wai Chi , Chen Haiyong , Au Dennis Cheuk Wing , Lee Rebecca Wing Yan , Mak Yim Wah , Yeung Wing Fai 
Published: March 2023

AbstractBackgroundSome traditional Chinese medicine (TCM)–based integrated health interventions have been used for depression, but pooled efficacy remains unknown.Aims and ObjectivesThis study aimed to systematically evaluate the efficacy of TCM‐based integrated health interventions for relieving depression.DesignSystematic review and meta‐analysis.MethodsA comprehensive literature search was conducted on 17 databases from inception up to June 2022. Randomised controlled trials (RCTs) that examined an integrated health intervention based on TCM theory for depression were included. The risk of bias was assessed using the second version of the Cochrane risk‐of‐bias tool for randomised trials, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation system.ResultsEighteen RCTs with a total of 1448 depressed participants were included. Health care providers, mainly nurses (14 studies), implemented TCM‐based integrated health interventions. The pooled results showed that TCM‐based integrated health interventions had larger effects on reducing depressive symptoms (15 studies; standardised mean difference = −2.05; 95% CI: −2.74, −1.37; p < .00001) compared with usual care at posttreatment but showed no significant difference contrasted to cognitive behavioural therapy (two studies, p = .31). However, the overall evidence was low.ConclusionsThe meta‐analysis results indicated that TCM‐based integrated health interventions were effective in reducing depression. However, the results should be interpreted with caution because of the low quality of the included studies. Future RCTs with rigorous designs should be conducted to provide robust evidence of the efficacy of TCM‐based integrated health interventions in treating depression.Relevance to clinical practiceTCM‐based integrated health interventions might be a potentially effective alternative for depression. Nurses could play an important role in designing and providing TCM‐based integrated nursing interventions for patients with depression.No patient or public contributionThis is a systematic review and meta‐analysis based on data from previous studies.
The Impact of Trustworthiness on the Association of Corporate Social Responsibility and Irresponsibility on Legitimacy
Authors: Hadani Michael 
Published: March 2023

AbstractResearch on corporate social responsibility (CSR) and corporate social irresponsibility (CSIR) has long argued both affect firms' legitimacy, for good or bad. Such research has ignored how ex‐ante corporate trustworthiness and associated attributions affect the association of CSR and CSIR on corporate normative legitimacy. Focusing on two unique aspects of corporate normative legitimacy evaluations – affect and misconduct – we argue that ex‐ante perceptions of firm trustworthiness moderate the associations among CSR and CSIR and different aspects of normative legitimacy. Utilizing comprehensive panel‐data analytical approaches for S&P 500 firms from 2000 to 2015, MSCI‐KLD data, mass‐media‐based measures of firm trustworthiness, including normative affect‐based legitimacy, and normative misconduct‐related‐legitimacy, our proposition is mostly supported, with surprising caveats. A post‐hoc analysis shows these associations vary based on public versus investors' affective‐legitimacy views. The findings of this study critically challenge extant scholarship and call for a nuanced view of the impact of CSR and CSIR on firm legitimacy.