bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of biogum thickener and properties of recoverable fracturing fluid based on environmental protection
Authors: Zhou Chengyu , Zeng Linghao , Zhao Jing , Mei Qixiang , Zhou Min , Xiao Ying , Zhang Qian , Fan Yuzhu , Zhang Peng 
Published: March 2023

AbstractA recyclable biogum thickener was developed and employed as the main agent to compound a fracturing fluid system in order to address the issue of the problematic recovery of fracturing fluid system. By using infrared (IR), nuclear magnetic resonance (NMR), X‐ray diffraction (XRD), and scanning electron microscopy (SEM), the physical characteristics and microstructure were examined. By using a rheometer, dynamic filtration loss, and an acid‐etching fracture conductivity device, respectively, the system's temperature and shear resistance, dynamic filtration loss, and fracture conductivity damage were studied. The system's gum‐breaking performance, formation water compatibility, and anti‐expansion performance were then measured in accordance with standards. As a result of shearing at 170 s−1 and 120°C for 2 h, the 4% biogum system's performance outperformed the other two systems in every way, according to the experimental findings. Its viscosity could also exceed 70 mPa · s. After breaking, the solution had a viscosity of 2.5 mPa · s, which was very compatible with the formation water. The system has a 90% anti‐swelling rate, a filtration loss coefficient of 5.14 × 10−5, strong infiltration ability, and negligible formation damage. The biogum system's recovery rate after field application is discovered to be around 50%.
Drawbacks of phase change models in simulating flashing of steam with a subsaturation downstream boundary condition
Authors: John Stanley , Lange Carlos F. 
Published: March 2023

AbstractThe development of phase change models applicable to a wide range of temperatures, pressures, and mass flow rates is primarily limited by the metastable or partially stable behaviour of the fluid. Due to this, the fluid does not change phase even after crossing saturation conditions. Most liquid–vapour phase change models have been developed primarily for the cavitation process where the phase change is not sustained, occurs in a very narrow region of space, or occurs under equilibrium conditions. In this paper, the mechanism of phase change is discussed along with the review of three different computational fluid dynamics (CFD)‐based phase change methods available in OpenFOAM, which are used to simulate flashing of steam, in applications related to steam assisted gravity drainage (SAGD) systems. The first method is based on barotropic compressibility (BC) used with the realizable turbulence model, the second combination is of mass transfer model (MTM) with the realizable turbulence model, and the third one is based on two fluid (TF) method along with a family of turbulence models. These methods are tested on a converging–diverging nozzle with pressure driven phase change. It is demonstrated that these methods are not able to adjust their physics to different depressurization rates, do not account for liquid to be in superheated conditions, and have significant discrepancies with experimental results. In the end, better approaches to model this category of phase change are discussed.
Manganese‐based polyanionic cathodes for sodium‐ion batteries
Authors: Niu Yubin , Zhao Yanan , Xu Maowen 
Published: March 2023

AbstractOwing to abundant resources and low cost, sodium‐ion batteries (SIBs) are sweeping the world at a rapid pace. The cathode is the key to determining the energy density of the battery, and polyanionic compounds have become a representative class of cathode materials due to their stable three‐dimensional framework structure, high operating voltage, and good safety. Vanadium‐based and iron‐based polyanionic compounds are highly regarded in academic communities, but environmental hazards or low energy densities have once overshadowed them in the practical arena. In contrast, manganese (Mn)‐based polyanion is one of the potential candidates in terms of cost, voltage, and environmental friendliness, besides, many noteworthy advances have been recorded in recent years. This review summarizes the current research progress of Mn‐based polyanions and discusses the challenges they face while looking forward to the future development of such materials and ideas to solve the key problems. It is expected to have a positive effect, that is, to attract more practitioners to focus on the practical way out of such materials.
Effect of biomaterial stiffness on cardiac mechanics in a biventricular infarcted rat heart model with microstructural representation of in situ intramyocardial injectate
Authors: Motchon Y. D. , Sack Kevin L. , Sirry M. S. , Kruger M. , Pauwels E. , Van Loo D. , De Muynck A. , Van Hoorebeke L. , Davies Neil H. , Franz Thomas 
Published: March 2023

AbstractIntramyocardial delivery of biomaterials is a promising concept for treating myocardial infarction. The delivered biomaterial provides mechanical support and attenuates wall thinning and elevated wall stress in the infarct region. This study aimed at developing a biventricular finite element model of an infarcted rat heart with a microstructural representation of an in situ biomaterial injectate, and a parametric investigation of the effect of the injectate stiffness on the cardiac mechanics. A three‐dimensional subject‐specific biventricular finite element model of a rat heart with left ventricular infarct and microstructurally dispersed biomaterial delivered 1 week after infarct induction was developed from ex vivo microcomputed tomography data. The volumetric mesh density varied between 303 mm−3 in the myocardium and 3852 mm−3 in the injectate region due to the microstructural intramyocardial dispersion. Parametric simulations were conducted with the injectate's elastic modulus varying from 4.1 to 405,900 kPa, and myocardial and injectate strains were recorded. With increasing injectate stiffness, the end‐diastolic median myocardial fibre and cross‐fibre strain decreased in magnitude from 3.6% to 1.1% and from −6.0% to −2.9%, respectively. At end‐systole, the myocardial fibre and cross‐fibre strain decreased in magnitude from −20.4% to −11.8% and from 6.5% to 4.6%, respectively. In the injectate, the maximum and minimum principal strains decreased in magnitude from 5.4% to 0.001% and from −5.4% to −0.001%, respectively, at end‐diastole and from 38.5% to 0.06% and from −39.0% to −0.06%, respectively, at end‐systole. With the microstructural injectate geometry, the developed subject‐specific cardiac finite element model offers potential for extension to cellular injectates and in silico studies of mechanotransduction and therapeutic signalling in the infarcted heart with an infarct animal model extensively used in preclinical research.
Oxygen Vacancy Promoted Generation of Monatomic Oxygen Anion over Ni2+‐Doped MgO for Efficient Glycolysis of Waste PET**
Authors: Lin Yuheng , Yang Deshuai , Meng Chaoyu , Si Chunying , Zhang Quanxing , Zeng Guixiang , Jiang Wei 
Published: March 2023

AbstractDeveloping efficient and eco‐friendly catalysts for selective degradation of waste polyethylene terephthalate (PET) is critical to the circular economy of plastics. Herein, we report the first monatomic oxygen anion (O−)‐rich MgO−Ni catalyst based on a combined theoretical and experimental approach, which achieves a bis(hydroxyethyl) terephthalate yield of 93.7 % with no heavy metal residues detected. DFT calculations and electron paramagnetic resonance characterization indicate that Ni2+ doping not only reduces the formation energy of oxygen vacancies, but also enhances local electron density to facilitate the conversion of adsorbed oxygen into O−. O− plays a crucial role in the deprotonation of ethylene glycol (EG) to EG− (exothermic by −0.6 eV with an activation barrier of 0.4 eV), which is proved effective to break the PET chain via nucleophilic attack on carbonyl carbon. This work reveals the potential of alkaline earth metal‐based catalysts in efficient PET glycolysis.
Soil surface treatments and precipitation timing determine seedling development across southwesternUSrestoration sites
Authors: Farrell Hannah L. , Munson Seth M. , Butterfield Bradley J. , Duniway Michael C. , Faist Akasha M. , Gornish Elise S. , Havrilla Caroline A. , Larios Loralee , Reed Sasha C. , Rowe Helen I. , Laushman Katherine M. , McCormick Molly L. 
Published: March 2023

AbstractRestoration in dryland ecosystems often has poor success due to low and variable water availability, degraded soil conditions, and slow plant community recovery rates. Restoration treatments can mitigate these constraints but, because treatments and subsequent monitoring are typically limited in space and time, our understanding of their applicability across broader environmental gradients remains limited. To address this limitation, we implemented and monitored a standardized set of seeding and soil surface treatments (pits, mulch, and ConMod artificial nurse plants) designed to enhance soil moisture and seedling establishment across RestoreNet, a growing network of 21 diverse dryland restoration sites in the southwestern USA over 3 years. Generally, we found that the timing of precipitation relative to seeding and the use of soil surface treatments were more important in determining seeded species emergence, survival, and growth than site‐specific characteristics. Using soil surface treatments in tandem with seeding promoted up to 3× greater seedling emergence densities compared with seeding alone. The positive effect of soil surface treatments became more prominent with increased cumulative precipitation since seeding. The seed mix type with species currently found within or near a site and adapted to the historical climate promoted greater seedling emergence densities compared with the seed mix type with species from warmer, drier conditions expected to perform well under climate change. Seed mix and soil surface treatments had a diminishing effect as plants developed beyond the first season of establishment. However, we found strong effects of the initial period seeded and of the precipitation leading up to each monitoring date on seedling survival over time, especially for annual and perennial forbs. The presence of exotic species exerted a negative influence on seedling survival and growth, but not initial emergence. Our findings suggest that seeded species recruitment across drylands can generally be promoted, regardless of location, by (1) incorporation of soil surface treatments, (2) employment of near‐term seasonal climate forecasts, (3) suppression of exotic species, and (4) seeding at multiple times. Taken together, these results point to a multifaceted approach to ameliorate harsh environmental conditions for improved seeding success in drylands, both now and under expected aridification.
Metapopulation regulation acts at multiple spatial scales: Insights from a century of seabird colony census data
Authors: Jeglinski Jana W. E. , Wanless Sarah , Murray Stuart , Barrett Robert T. , Gardarsson Arnthor , Harris Mike P. , Dierschke Jochen , Strøm Hallvard , Lorentsen Svein‐Håkon , Matthiopoulos Jason 
Published: March 2023

AbstractDensity‐dependent feedback is recognized as important regulatory mechanisms of population size. Considering the spatial scales over which such feedback operates has advanced our theoretical understanding of metapopulation dynamics. Yet, metapopulation models are rarely fit to time‐series data and tend to omit details of the natural history and behavior of long‐lived, highly mobile species such as colonial mammals and birds. Seabird metapopulations consist of breeding colonies that are connected across large spatial scales, within a heterogeneous marine environment that is increasingly affected by anthropogenic disturbance. Currently, we know little about the strength and spatial scale of density‐dependent regulation and connectivity between colonies. Thus, many important seabird conservation and management decisions rely on outdated assumptions of closed populations that lack density‐dependent regulation. We investigated metapopulation dynamics and connectivity in an exemplar seabird species, the Northern gannet (Morus bassanus), using more than a century of census data of breeding colonies distributed across the Northeast Atlantic. We developed and fitted these data to a novel hierarchical Bayesian state‐space model, to compare increasingly complex scenarios of metapopulation regulation through lagged, local, regional, and global density dependence, as well as different mechanisms for immigration. Models with conspecific attraction fit the data better than the equipartitioning of immigrants. Considering local and regional density dependence jointly improved model fit slightly, but importantly, future colony size projections based on different mechanistic regulatory scenarios varied widely: a model with local and regional dynamics estimated a lower metapopulation capacity (645,655 Apparently Occupied Site [AOS]) and consequently higher present saturation (63%) than a model with local density dependence (1,367,352 AOS, 34%). Our findings suggest that metapopulation regulation in the gannet is more complex than traditionally assumed, and highlight the importance of using models that consider colony connectivity and regional dynamics for conservation management applications guided by precautionary principles. Our study advances our understanding of metapopulation dynamics in long‐lived colonial species and our approach provides a template for the development of metapopulation models for colonially living birds and mammals.
Association between MMP2 gene polymorphisms and dilated cardiomyopathy in a Chinese Han population
Authors: Li Shiyang , Zeng Xiaobin , Wang Shihai , Xie Xiaoshuang , Lan Jianjun 
Published: March 2023

AbstractAimsDilated cardiomyopathy (DCM) belongs to the common types of cardiomyopathies. The pathogenesis remains unclear despite the fact that various genes have been found associated with DCM. MMP2 is a zinc‐dependent and calcium‐containing secreted endoproteinases, which could cleave a broad spectrum of substrates including extracellular matrix components and cytokines. It has proved to play an important role in the cardiovascular diseases. This study aimed to investigate the potential role of MMP2 gene polymorphisms in DCM susceptibility and prognosis in a Chinese Han population.Methods and resultsA total of 600 idiopathic DCM patients and 700 healthy controls were enrolled. Patients with contact information were followed up for a median period of 28 months. Three tagged single nucleotide polymorphisms (rs243865, rs2285052, and rs2285053) in the promoter of MMP2 gene were genotyped. A series of function analysis were conducted to illuminate the underlying mechanism. The frequency of rs243865‐C allele was increased in DCM patients when compared with healthy controls (P = 0.001). Genotypic frequencies of rs243865 were associated with the susceptibility of DCM in the codominant, dominant, and overdominant models (P < 0.05). Besides, rs243865‐C allele presented a correlation with the poor prognosis of DCM patients in both dominant (HR = 2.0, 95% confidence interval [CI] = 1.14–3.57, P = 0.017) and additive (HR = 1.85, 95% CI = 1.09–3.13, P = 0.02) model. The statistical significance remained after adjustment for sex, age, hypertension, diabetes, hyperlipidaemia, and smoking status. There were significant differences in left ventricular end‐diastolic diameter and left ventricular ejection fraction between rs243865‐CC and CT genotypes. Functional analysis indicated that rs243865‐C allele increased luciferase activity and the mRNA expression level of MMP2 by facilitating ZNF354C binding.ConclusionsOur study suggested that MMP2 gene polymorphisms were associated with DCM susceptibility and prognosis in the Chinese Han population.
Genes-to-Pathways Species Conservation Analysis: Enabling the Exploration of Conservation of Biological Pathways and Processes Across Species
Authors: Rivetti Claudia , Houghton Jade , Basili Danilo , Hodges Geoff , Campos Bruno 
Published: March 2023

Abstract
The last two decades have witnessed a strong momentum toward integration of cell-based and computational approaches in safety assessments. This is fueling a global regulatory paradigm shift toward reduction and replacement of the use of animals in toxicity tests while promoting the use of new approach methodologies. The understanding of conservation of molecular targets and pathways provides an opportunity to extrapolate effects across species and ultimately to determine the taxonomic applicability domain of assays and biological effects. Despite the wealth of genome-linked data available, there is a compelling need for improved accessibility, while ensuring that it reflects the underpinning biology. We present the novel pipeline Genes-to-Pathways Species Conservation Analysis (G2P-SCAN) to further support understanding on cross-species extrapolation of biological processes. This R package extracts, synthetizes, and structures the data available from different databases, that is, gene orthologs, protein families, entities, and reactions, linked to human genes and respective pathways across six relevant model species. The use of G2P-SCAN enables the overall analysis of orthology and functional families to substantiate the identification of conservation and susceptibility at the pathway level. In the present study we discuss five case studies, demonstrating the validity of the developed pipeline and its potential use as species extrapolation support. We foresee this pipeline will provide valuable biological insights and create space for the use of mechanistically based data to inform potential species susceptibility for research and safety decision purposes. Environ Toxicol Chem 2023;42:1152–1166. © 2023 UNILEVER GLOBAL IP LTD. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Modification of rheological properties of animal and vegetable proteins treated with high‐intensity ultrasound: A review
Authors: Flores‐Jiménez Nitzia Thalía , Ulloa José Armando , Urías‐Silvas Judith Esmeralda , Hidalgo‐Millán Antonio 
Published: March 2023

AbstractThe rheological properties of proteins play a role important in the fluid flow, pump selection, equipment design, and product development. In addition, it has been observed that the texture and mouthfeel of foods depend on the viscoelastic properties of their ingredients, especially those that show both elastic and viscous behavior, such as proteins. To improve the functional properties, including the rheological ones, proteins have been subjected to some physical treatments, such as ultrasound, which is considered an emerging green technology. Changes in the properties of proteins by high‐intensity ultrasound vary according to the equipment used, power, frequency, and time of sonication, as well as the intrinsic characteristics of the studied proteins. As pretreatment, ultrasound affects the rheological properties of proteins such as viscosity and storage and loss moduli due to the structural modification of its polypeptide chain, as a consequence of the cavitation phenomenon. In this review, we present the main results of the effect of high‐intensity ultrasound on the rheological properties of animal and vegetable proteins subjected to different conditions such as ultrasound device, power, frequency, wave amplitude, and exposure time mainly. In this context, the information from studies of the impact of ultrasound on the rheological properties of proteins from animal and vegetable sources is important to diversify its possible use as a food ingredient.
A minimal model for the influence of equilibrium positions on brake squeal
Authors: Koch Sebastian , Gräbner Nils , von Wagner Utz 
Published: March 2023

AbstractThe phenomenon brake squeal has been an ongoing topic for decades, both in the automotive industry and in science. Although there is agreement on the excitation mechanism of brake squeal, namely self‐excitation due to frictional forces between the disk and the pad, in the subject of squeal it is very complex to discover all relevant effects and to take them into account. Several of these problems are related to nonlinearities, for example, in the contact between pad and disk or drum or in the behavior of the brake pad material. One of these nonlinear effects, which has been almost completely neglected so far, is that the brake can engage, mainly due to the bushing and joint elements within the brake, different equilibrium positions. This in fact has serious influence on the noise behavior as shown in experimental studies. For example, it is observed in experiments that, despite identical operating parameters, squeal sometimes occurs and sometimes not. In initial experimental studies, this could be related to the engaged equilibrium position. Following these experimental studies, the present paper introduces a minimal model by extending the well‐known minimal model by Hoffmann et al. by corresponding elements and nonlinearities allowing the system to engage different equilibrium positions. As will be presented, the stability behavior strongly depends on the engaged equilibrium position. Therefore, the minimal model represents the key experimentally observed issues. Additionally, a limit cycle behavior can also be observed.
The role of glial cells in Zika virus‐induced neurodegeneration
Authors: Quincozes‐Santos André , Bobermin Larissa Daniele , Costa Naithan Ludian Fernandes , Thomaz Natalie K. , Almeida Rômulo Rodrigo de Souza , Beys‐da‐Silva Walter O. , Santi Lucélia , Rosa Rafael L. , Capra Daniela , Coelho‐Aguiar Juliana M. , DosSantos Marcos Fabio , Heringer Manoela , Cirne‐Lima Elizabeth O. , Guimarães Jorge Almeida , Schuler‐Faccini Lavínia , Gonçalves Carlos‐Alberto , Moura‐Neto Vivaldo , Souza Diogo Onofre 
Published: March 2023

AbstractZika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated with microcephaly in neonates. However, clinical and experimental evidence indicate that ZIKV also affects the adult nervous system. In this regard, in vitro and in vivo studies have shown the ability of ZIKV to infect glial cells. In the central nervous system (CNS), glial cells are represented by astrocytes, microglia, and oligodendrocytes. In contrast, the peripheral nervous system (PNS) constitutes a highly heterogeneous group of cells (Schwann cells, satellite glial cells, and enteric glial cells) spread through the body. These cells are critical in both physiological and pathological conditions; as such, ZIKV‐induced glial dysfunctions can be associated with the development and progression of neurological complications, including those related to the adult and aging brain. This review will address the effects of ZIKV infection on CNS and PNS glial cells, focusing on cellular and molecular mechanisms, including changes in the inflammatory response, oxidative stress, mitochondrial dysfunction, Ca2+ and glutamate homeostasis, neural metabolism, and neuron–glia communication. Of note, preventive and therapeutic strategies that focus on glial cells may emerge to delay and/or prevent the development of ZIKV‐induced neurodegeneration and its consequences.