bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative evaluation of fracture resistance using different techniques for the reattachment of fractured maxillary central incisor – an in vitro study
Authors: Rashmi Saini , Kumar Saini V. 
Published: July 2023

Objective
To comparatively evaluate fracture resistance of different techniques for the reattachment of fractured maxillary central incisors.

Materials and Methods
Sixty intact freshly extracted permanent maxillary central incisors were selected and randomly divided into four groups of 15 each one of control (I) and three experimental groups (II, III, IV) according to the technique of reattachment. The incisal third of the experimental groups were sectioned horizontally. Group I: the teeth were kept intact without sectioning. Group II: an internal dentinal groove (1 mm deep and 1 mm wide). Group III: a pinhole (1.5 mm depth and 1.5 mm diameter). Fractured fragments in group II and group III were reattached using composite resin. Group IV: two vertical grooves (1 mm deep, 1 mm wide, and 4 mm length) with fiber-reinforced composite post (Everstick, GC America). After 24 h of restoration, all samples in each group were then subjected to thermocycling at 5±1 and 55±1°C for 500 cycles each cycle. All the samples were mounted on the universal testing machine (instron). The force was then applied at an angle of 45° of each tooth in a labial to palatal direction at a cross-head speed of 1 mm/min until fractured occurred and the obtained values were subjected to statistical analysis.

Results
The results showed that the mean fracture resistance of group I was the highest followed by group III, group IV, and group II the least (group II < group IV < group III < group I). Comparing the mean fracture resistance of four groups, analysis of variance showed significantly different fracture resistance among the groups (F = 22.93, P < 0.001).

Conclusion
No material and technique can restore the strength of intact tooth. However, reattachment techniques can be considered as an alternate method, when the fractured fragment is available with adequate size and appropriately preserved margins.
Evaluation of intraarticular injection of hyaluronic acid with platelet rich plasma for treatment of temporomandibular joint anterior disc displacement with and without reduction
Authors: Abd ElMonem Arboud Karim A. , Shoushan Mohamed M. , El Sharif Ahmed M. 
Published: July 2023

Background
For patients who failed to respond to conservative measures for temporomandibular joint (TMJ) internal derangement after arthrocentesis, several intraarticular injections have been shown to be an effective treatment modality to reduce pain, improve joint movement and range of motion.

Purpose
Our study aim was to evaluate the efficacy of intraarticular injection of hyaluronic acid (HA) and platelet rich plasma (PRP) in the treatment of TMJ anterior disc displacement with (DDwR) and without (DDwoR) reduction after arthrocentesis.

Patients and methods
This prospective clinical study involved 20 patients with TMJ anterior disc displacement, assigned into two equal groups. Group 1 included 10 patients with DDwR and group 2 included 10 patients with DDwoR. Both groups were treated with arthrocentesis and intraarticular injection of 1 ml of equal amount of HA and PRP into the superior joint space. Visual analog scale (VAS), maximum mouth opening (MMO), lateral jaw movements and joint clicking sounds were assessed at each follow up period (1 week, 1 month, 3 months, and 6 months) for both groups. The collected data was then statistically analyzed.

Results
Pain intensity decreased in both groups; in group 1, mean VAS decreased from 6.9 to 0.6 while in group 2, VAS decreased from 6.8 to 0.8. MMO mean for group 1 increased from 32.4 to 44.9 mm. In group 2, MMO increased from 24 to 34.6 mm. TMJ lateral movement for group 1 increased from 6 to 8.7 mm and for group 2, it increased from 5.5 to 7.2 mm. Number of patients with TMJ clicking in group 1 decreased from 8 to 1 while in group 2, patients had no clicking sounds from the start. MRIs showed no change before and after study in both groups as disc remained at same position.

Conclusions
Intraarticular injection of HA and PRP mixture was found to be clinically effective in the treatment of TMJ disorders in both anterior DDwR and DDwoR groups; however, no significant difference was noticed on the disc position on the MRI.
Prevalence of selected dental anomalies in children and adolescents in Turkey
Authors: Bodrumlu Ebru Hazar , Tazegül Fulden Senyurt 
Published: July 2023

Aim
This study aims to evaluate the prevalence of dental anomalies and the tendency of dental anomalies among the teeth in Turkey.

Patients and methods
This retrospective study was designed on panoramic radiographs of randomly selected 4105 patients that applied to Zonguldak Bulent Ecevit University, Faculty of Dentistry. In the study, nine types of dental anomalies were analyzed statistically on the panoramic radiography images of the patients, including one supernumerary teeth, odontoma, congenitally missing teeth, ectopic eruption, rotation, impacted teeth, fusion, dilaceration, and morphological defects.

Results
The prevalence of a dental anomaly among all evaluated patients was 26.7%. The most common anomaly was found to be congenital missing teeth with a prevalence of 14.2%. Odontoma was found to be the least common anomaly with a prevalence of 01%. Congenital missing teeth were most frequently observed in the mandibular second premolar.

Conclusion
The prevalence of dental anomalies in the study population was very high. Nine different anomalies were detected and congenitally missing teeth are the most common developmental dental anomaly in the study. The prevalence of dental anomalies may vary and early diagnosis of dental anomalies is important for treatment planning and success.
Confinement width and inflow-to-sediment discharge ratio control the morphology and braiding intensity of submarine channels: insights from physical experiments and reduced-complexity models
Authors: Huang Sam Y. J. , Lai Steven Y. J. , Limaye Ajay B. , Foreman Brady Z. , Paola Chris 
Published: July 2023

Abstract. Submarine channels conveying sediment gravity flows are often topographically confined, but the effect of confinement width on channel morphodynamics is incompletely understood. We use physical experiments and a reduced-complexity model to investigate the effects of confinement width (B) and the inflow-to-sediment discharge ratio (Qin/Qs) on the evolution of submarine braided channels. The results show that a larger confinement width results in increased active braiding intensity (BIA) and that BIA takes longer to stabilize (i.e., a longer critical time; tc). At a fixed confinement width, a higher Qin/Qs slightly decreases the BIA. Digital elevation models of difference (DoD) of the experiments allow measurement of the morphological active width (Wa) of the submarine channels and the bulk morphological change (Vbulk) within an experiment, defined as the sum
of total erosion and deposition. We find that Wa and Vbulk are proportional to B. We further confirm that BIA is proportional to both dimensionless sediment–stream power (ω**) and dimensionless stream power (ω*). These trends are consistent for submarine braided channels both with and without confinement width effects. Furthermore, we built a reduced-complexity model (RCM) that can simulate flow bifurcation and confluence of submarine braided channels. The simulated flow distribution provides reliable predictions of flow depth and sediment transport rate in the experiments. Using kernel density estimation (KDE) to forecast the probability and trends of cross-sectional flow distribution and corresponding BIA under extreme events, we find that
skewness of the flow distribution decreases as discharge increases. The
development of braided submarine channels, shown here to extend to
conditions of topographic confinement, suggests that factors not modeled
here (e.g., fine sediment) may be necessary to explain the abundance of
single-thread submarine channels in nature.
Engineering Atom‐Scale Cascade Catalysis via Multi‐Active Site Collaboration for Ampere‐Level CO2 Electroreduction to C2+ Products
Authors: Jin Chenghao , Lin Yue , Wang Yanan , Shi Jingbo , Li Ren , Liu Yijiang , Yue Zongye , Leng Kunyue , Zhao Yafei , Wang Yi , Han Xiao , Qu Yunteng , Bai Jinbo 
Published: January 2025

AbstractElectrochemical reduction of CO2 to value‐added multicarbon (C2+) productions offers an attractive route for renewable energy storage and CO2 utilization, but it remains challenging to achieve high C2+ selectivity at industrial‐level current density. Herein, a Mo1Cu single‐atom alloy (SAA) catalyst is reported that displays a remarkable C2+ Faradaic efficiency of 86.4% under 0.80 A cm−2. Furthermore, the C2+ partial current density over Mo1Cu reaches 1.33 A cm−2 with a Faradaic efficiency surpasses 74.3%. The combination of operando spectroscopy and density functional theory (DFT) indicates the as‐prepared Mo1Cu SAA catalyst enables atom‐scale cascade catalysis via multi‐active site collaboration. The introduced Mo sites promote the H2O dissociation to fabricate active *H, meanwhile, the Cu sites (Cu0) far from Mo atom are active sites for the CO2 activation toward CO. Further, CO and *H are captured by the adjacent Cu sites (Cu&+) near Mo atom, accelerating CO conversion and C─C coupling process. Our findings benefit the design of tandem electrocatalysts at atomic scale for transforming CO2 to multicarbon products under a high conversion rate.
Inflammation Targeting‐Triggered Healing Hydrogel for In Situ Reconstruction of Colonic Mucosa
Authors: Chen Gaoxian , Li Xinyi , Xu Wei , Wang Haoze , Jiang Yichao , Shi Ruofan , Zhu Chengying , Xiao Zeyu 
Published: January 2025

AbstractInflammatory bowel disease (IBD) is characterized by intestinal mucosal damage that exacerbates inflammation and promotes disease recurrence. Although hydrogel‐based therapies have shown potential for mucosal repair, challenges remain due to inadequate targeting and low hydrogel density, leading to ongoing infiltration of harmful substances and delayed mucosal healing. In this study, an inflammation‐targeting‐triggered healing hydrogel (ITTH hydrogel) is developed, composed of polyvinyl alcohol‐alginate microgels (PALMs) and a cyclodextrin polymer crosslinker (CPC). This hydrogel specifically targets inflamed colonic sites and crosslinks in situ to form a dense network. The results demonstrate that the ITTH hydrogel adheres effectively to inflamed colonic tissue in both IBD mouse models and human samples. The dense crosslinked network acts like the mucosal barrier, preventing the penetration of detrimental substances such as bacteria and small molecules, thereby protecting the underlying mucosal tissue. Furthermore, the ITTH hydrogel significantly improved therapeutic outcomes in mice with dextran sulfate sodium (DSS)‐induced colitis. These findings suggest that the ITTH hydrogel is a promising candidate for in situ reconstruction of colonic mucosa and the treatment of IBD.
Diagnosing Epilepsy with Normal Interictal EEG Using Dynamic Network Models
Authors: Myers Patrick , Gunnarsdottir Kristin M. , Li Adam , Razskazovskiy Vlad , Craley Jeff , Chandler Alana , Wyeth Dale , Wyeth Edmund , Zaghloul Kareem A. , Inati Sara K. , Hopp Jennifer L. , Haridas Babitha , Gonzalez‐Martinez Jorge , Bagíc Anto , Kang Joon‐yi , Sperling Michael R. , Barot Niravkumar , Sarma Sridevi V. , Husari Khalil S. 
Published: January 2025

ObjectiveWhereas a scalp electroencephalogram (EEG) is important for diagnosing epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of routine EEGs show interictal epileptiform discharges (IEDs) and overall misdiagnosis rates of epilepsy are 20% to 30%. We aim to demonstrate how network properties in EEG recordings can be used to improve the speed and accuracy differentiating epilepsy from mimics, such as functional seizures – even in the absence of IEDs.MethodsIn this multicenter study, we analyzed routine scalp EEGs from 218 patients with suspected epilepsy and normal initial EEGs. The patients’ diagnoses were later confirmed based on an epilepsy monitoring unit (EMU) admission. About 46% ultimately being diagnosed with epilepsy and 54% with non‐epileptic conditions. A logistic regression model was trained using spectral and network‐derived EEG features to differentiate between epilepsy and non‐epilepsy. Of the 218 patients, 90% were used for training and 10% were held out for testing. Within the training set, 10‐fold cross validation was performed. The resulting tool was named “EpiScalp.”ResultsEpiScalp achieved an area under the curve (AUC) of 0.940, an accuracy of 0.904, a sensitivity of 0.835, and a specificity of 0.963 in classifying patients as having epilepsy or not.InterpretationEpiScalp provides an accurate diagnostic aid from a single initial EEG recording, even in more challenging epilepsy cases with normal initial EEGs. This may represent a paradigm shift in epilepsy diagnosis by deriving an objective measure of epilepsy likelihood from previously uninformative EEGs. ANN NEUROL 2025
Ultrahochfester Beton für die Instandsetzung und Verstärkung von Brücken – Teil 1
Authors: Schmidt Michael , Leutbecher Torsten , Fehling Ekkehard , Middendorf Bernhard 
Published: January 2025

AbstractEine zunehmende Zahl an Straßenbrücken in Deutschland weist Defizite hinsichtlich Standsicherheit und Dauerhaftigkeit auf. Ein Ersatz der Bauwerke durch Neubauten ist kostenintensiv und bindet erhebliche materielle und personelle Ressourcen. Wie ein Blick in die Nachbarländer zeigt, stellt die Instandsetzung bzw. Verstärkung von Brückenüberbauten mittels dünner bewehrter Deckschichten aus ultrahochfestem Beton (UHFB) eine kostengünstige und vor allem dauerhafte Alternative zum Ersatzneubau dar. Im ersten Teil dieses Beitrags werden die grundsätzlichen Anwendungsmöglichkeiten von UHFB im Brückenbestand vorgestellt und Konstruktionsweisen erläutert. Die besondere Eignung von UHFB für dieses Einsatzgebiet resultiert aus der Dichtigkeit seines Gefüges und seinem Widerstand gegen jede Form chemischen und physikalischen Angriffs, sodass UHFB ohne weitere Schutzmaßnahmen auch im Fahrbahnbereich eingesetzt werden kann. UHFB unterscheidet sich in seinen Stoffeigenschaften grundlegend von normalfestem und hochfestem Beton. Daher werden diese Aspekte im Detail vergleichend beleuchtet. Des Weiteren werden die wichtigsten mechanischen Eigenschaften dargestellt. Die Informationen können bspw. als Grundlage für eine Zustimmung im Einzelfall, für die Entwicklung oder Ergänzung technischer Regelwerke oder für die technischen Inhalte des Bauvertrags genutzt werden. Auf Aspekte der Ausführung und der Qualitätssicherung wird im zweiten Teil dieses Beitrags eingegangen.
Steigerung der Bearbeitungsgenauigkeit von Betonoberflächen durch robotergestütztes Fräsen
Authors: Hägle Marius , Stöhr Ben , Stark Alexander 
Published: January 2025

AbstractDie Automatisierung von Prozessen im Bauwesen erlangt zunehmend an Bedeutung, um präzise materialeffiziente Bauteile herstellen zu können und dem Fachkräftemangel entgegenzuwirken. Ein vielversprechender Anwendungsbereich ist die robotergestützte Nachbearbeitung von modularen oder wiedergewonnenen Stahlbetonbauteilen. Für modulare Fertigteilkonstruktionen oder im Sinne der Kreislaufwirtschaft sind insbesondere Trockenfugen mit sehr hoher Genauigkeit erforderlich, um die Bildung von Spannungsspitzen zu vermeiden und die Fertigungstoleranzen im Fügeprozess einzuhalten. Der Einsatz robotergestützter Bearbeitungsverfahren erfordert hierfür eine genaue Kenntnis der Arbeitsgenauigkeit. In diesem Beitrag wird die Arbeitsgenauigkeit für das Betonfräsen mit Industrierobotern zur Nachbearbeitung von Betonbauteilen systematisch untersucht und Einflussfaktoren identifiziert. Mithilfe von Beschleunigungsmessungen wird die Veränderung des Schwingungsverhaltens des Werkzeugs während des Fertigungsprozesses erfasst. Dies ermöglicht eine einfache und schnelle Qualitätskontrolle der gefrästen Oberflächen.
Green Synthesis of ZnO Nanoparticles Using Ficus benghalensis for Visible Light–Driven Photocatalytic Degradation of Crystal Violet and Antibacterial and Antibiofilm Activities
Authors: Karthiga Perumal , Chitra Kethrabalan , Wadaan Mohammad Ahmad , Mythili R. , Lee Jintae , Bharathi Devaraj 
Published: January 2025

ABSTRACTCrystal Violet (CV) is a vibrant and harmful dye known for its toxicity to aquatic life and potential carcinogenic effects on humans. This study explores the removal of CV through photocatalysis driven by visible light, as well as examining the antibacterial and antibiofilm characteristics of zinc oxide nanoparticles (ZnO NPs) synthesized from the aerial roots of Ficus benghalensis. Various characterization techniques were employed to confirm the optical properties, crystal lattices, and morphology of ZnO NPs. TEM images showed that the ZnO NPs had a spherical shape, with an average size of 40 to 80 nm. The photocatalytic analysis revealed that the synthesized ZnO NPs exhibited substantial activity under visible light, effectively degrading 90.6% of CV in an aqueous solution. The antibacterial activity of synthesized ZnO NPs was evaluated against clinically relevant bacterial strains such as Pseudomonas aeruginosa and Bacillus subtilis, revealing notable zones of inhibition. Moreover, the ZnO NPs exhibited antibiofilm activity of 96.8 ± 0.5% and 98.3 ± 0.3% against P. aeruginosa and Staphylococcus aureus, respectively. In conclusion, this study demonstrated the potential of the synthesized ZnO NPs as a sustainable solution for wastewater treatment and antibacterial applications.
Potential Role of Nonverbal Synchrony in Psychotherapy: A Meta‐Analysis
Authors: Gregorini Camilla , De Carli Pietro , Parolin Laura Antonia Lucia , Tschacher Wolfgang , Preti Emanuele 
Published: January 2025

ABSTRACTBackgroundInterpersonal synchrony entails the coordination of verbal and nonverbal features underlying communicative patterns. However, the strength of the association between the synchronisation of nonverbal features (movements and vocal tones) and therapeutic alliance and outcome remains unclear.ObjectivesThis meta‐analysis aimed to investigate the strength of (1) the association between nonverbal synchrony and perception of alliance reported by the patients, (2) the association between nonverbal synchrony and therapeutic outcome, and (3) the moderating role of the type of psychotherapeutic approach.MethodsThis meta‐analysis included 11 studies. Inclusion criteria were studies that utilised a quantitative measure of nonverbal synchrony in association with measures of therapeutic alliance and outcome.ResultsRandom effects model indicated that nonverbal synchrony was significantly associated with the alliance perceived by the patient (r = 0.19; 95% CI: 0.02–0.35; z = 2.18, p = 0.02); however, it was not significantly associated with the therapeutic outcome (r = 0.22; 95% CI: −0.04 to 0.47; z = 1.65, p = 0.09). No moderating effects were observed for the type of therapeutic approach.ConclusionsThese findings support the view that nonverbal synchrony is a central aspect of psychotherapy and highlight the possible interdependence between nonverbal synchrony and therapeutic alliance.
A Delphi Study Exploring Psychotherapeutic Priorities for Third and Fourth Generation Holocaust Survivors
Authors: Olstein Justin , Sheen Jade , Reupert Andrea 
Published: January 2025

ABSTRACTBackgroundThe intergenerational effects of the Holocaust have been far‐reaching, with recent research demonstrating effects with regard to the survivors' grandchildren (third generation) and great‐grandchildren (fourth generation). However, little is known about how these effects should be broached by mental health clinicians.AimsThis study aimed to develop a preliminary consensus around the Holocaust‐related areas most prioritised for discussion by third and fourth generation members in a psychotherapeutic context.Materials and MethodsA two‐round online Delphi survey was used to facilitate this, and 29 third and fourth generation descendants participated. In round one, participants responded to open‐ended questions concerning how the intergenerational impacts of the Holocaust might be explored in therapy. In round two, participants rated statements derived from round one data in terms of their perceived importance.ResultsTen therapeutic priorities were identified, revolving around a need for clinicians to explore the potential for intergenerational traumatisation and fears relating to experiencing antisemitism.Discussion and ConclusionThe study's results indicate that the spectre of the Holocaust remains a prominent fixture in the lives of third and fourth generation descendants, requiring clinicians working with them to have particular skills and knowledge.
Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report
Authors: Babaee Marzieh , Javadzadeh Mohsen , Hazeghi Ali 
Published: January 2025

ABSTRACTIntrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplinary management are crucial. Vigilant neurological monitoring is essential for pediatric acute lymphoblastic leukemia patients receiving intrathecal chemotherapy.
A Real‐World Disproportionality Analysis of Histamine H2‐Receptors Antagonists (Famotidine): A Pharmacovigilance Study Based on Spontaneous Reports in the FDA Adverse Event Reporting System
Authors: Zhang Dongdong , Cai Ying , Sun Yixin , Zeng Peiji , Wang Wei , Wang Wenhui , Jiang Xiaohua , Lian Yifan 
Published: January 2025

ABSTRACTFamotidine is an H2 receptor antagonist and is currently used on a large scale in gastroenterology. However, Famotidine may also cause severe toxicity to organ systems, including the blood system, digestive system, and urinary system. The objective of this study was to scientifically and systematically investigate the adverse events (AEs) of Famotidine in the real world through the FDA Adverse Event Reporting System (FAERS) database. A disproportionality analysis was used to quantify the signals of AEs associated with Famotidine in FAERS data from the first quarter of 2004 to the first quarter of 2023. The clinical features, onset time, oral and intravenous administration and severe consequences of Famotidine induced AEs were further analyzed. Among the four tests, we found several AEs that were not mentioned in the drug label. For example, abdominal pain upper, abdominal discomfort, dyspepsia, liver disorder, gastrooesophageal reflux disease, and rhabdomyolysis. These AEs are consistent with the drug instructions. Interestingly, we found several unreported AEs, such as: cerebral infarction, hypocalcaemia, hallucination, visual, hypomagnesaemia, hypoparathyroidism, diabetes insipidus, vulvovaginal candidiasis, retro‐orbital neoplasm, neuroblastoma recurrent, and malignant cranial nerve neoplasm. Most of our findings are consistent with clinical observations and drug labels, and we also found possible new and unexpected AEs signals, which suggest the need for prospective clinical studies to confirm these results and explain their relationships. Our findings provide valuable evidence for further safety studies.