bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of dielectric breakdown in liquid xenon with XeBrA: The xenon breakdown apparatus
Authors: Watson J. , Olcina I. , Soria J. , McKinsey D. N. , Kravitz S. , Deck E. E. , Bernard E. P. , Tvrznikova L. , Waldron W. L. , Riffard Q. , O’Sullivan K. 
Published: January 2023

Maintaining the electric fields necessary for the current generation of noble liquid time projection chambers (TPCs), with drift lengths exceeding 1 m, requires a large negative voltage applied to their cathode. Delivering such high voltage is associated with an elevated risk of electrostatic discharge and electroluminescence, which would be detrimental to the performance of the experiment. The Xenon Breakdown Apparatus (XeBrA) is a 5-l, high voltage test chamber built to investigate the contributing factors to electrical breakdown in noble liquids. In this work, we present the main findings after conducting scans over stressed electrode areas, surface finish, pressure, and high voltage ramp speed in the medium of liquid xenon. Area scaling and surface finish were observed to be the dominant factors affecting breakdown, whereas no significant changes were observed with varying pressure or ramp speed. A general rise in both the anode current and photon rate was observed in the last 30 s, leading up to a breakdown, with a marked increase in the last couple of seconds. In addition, the position of breakdowns was reconstructed with a system of high-speed cameras and a moderate correlation with the Fowler–Nordheim field emission model was found. Tentative evidence for bubble nucleation being the originating mechanism of breakdown in the liquid was also observed. We deem the results presented in this work to be of particular interest for the design of future, large TPCs, and practical recommendations are provided.
Atmospheric turbulence and wildland fires: a review
Authors: Heilman Warren E. 
Published: January 2023

The behaviour of wildland fires and the dispersion of smoke from those fires can be strongly influenced by atmospheric turbulent flow. The science to support that assertion has developed and evolved over the past 100+ years, with contributions from laboratory and field observations, as well as modelling experiments. This paper provides a synthesis of the key laboratory- and field-based observational studies focused on wildland fire and atmospheric turbulence connections that have been conducted from the early 1900s through 2021. Included in the synthesis are reports of anecdotal turbulence observations, direct measurements of ambient and fire-induced turbulent flow in laboratory and wildland environments, and remote sensing measurements of fire-induced turbulent plume dynamics. Although considerable progress has been made in advancing our understanding of the connections between atmospheric turbulence and wildland fire behaviour and smoke dispersion, gaps in that understanding still exist and are discussed to conclude the synthesis.
Visual function impairment in patients suffering from visually induced motion sickness. A preliminary observational longitudinal study
Authors: Gabriele Leonardo , De Angelis Sara , Roncagli Vittorio , Tramontano Marco , Manzari Leonardo , Gabriele Domenico 
Published: January 2023

Objective
Visually induced Motion Sickness (VIMS) is a side effect induced by the physical motion of the person or visual motion that adversely affects otherwise individuals and decreases safety in situations that require high levels of concentration. The exact mechanisms behind the emergence of VIMS are still unknown but can be triggered by direct or indirect stimuli due to mismatches in the visual-vestibular autonomic pathways. The aim of this preliminary study was to explore the presence of visual dysfunctions in patients suffering from VIMS and then evaluate the potential role of a customized visual training (VT) on their perceived sickness symptoms.

Methods
A total of 9.675 medical records of patients who referred motion sickness were reviewed; 455 patients with a diagnosis of VIMS were included. A total of 95 patients (86 females and 9 males, mean age of 37,68 ± 9.20 years) met the inclusion criteria and were enrolled in this study. Two evaluation sessions were carried out immediately before (T0) and after 16 weeks (T1) of visual training (VT). The main goal of VT was to facilitate the visual center-periphery integration. VT was performed 1 day/week/16 weeks under therapist supervision in the Optometric centre and 5 days/week/16 weeks at home without supervision.

Results
The within-subjects comparison at times T0–T1 showed significant improvement of the symptoms in all the included patients.

Conclusion
Our results support the hypothesis that patients suffering from VIMS may present also a visual function impairment that can increase the dizziness-related symptoms. Furthermore, visual training can help patients with VIMS and visual dysfunction in reducing capture discomfort, stomach awareness, and nausea.
Burst Phase Distribution of SGR J1935+2154 Based on Insight-HXMT
Authors: Lu Xue-Feng , Song Li-Ming , Ge Ming-Yu , Tuo You-Li , Zhang Shuang-Nan , Qu Jin-Lu , Cai Ce , Xie Sheng-Lun , Liu Cong-Zhan , Li Cheng-Kui , Fu Yu-Cong , Xu Ying-Chen , Li Tian-Ming 
Published: January 2023

Abstract
On 2020 April 27, the soft gamma-ray repeater SGR J1935+2154 entered its intense outburst episode again. Insight-HXMT carried out about one month observation of the source. A total number of 75 bursts were detected during this activity episode by Insight-HXMT, and persistent emission data were also accumulated. We report on the spin period search result and the phase distribution of burst start times and burst photon arrival times of the Insight-HXMT high energy detectors and Fermi/Gamma-ray Burst Monitor (GBM). We find that the distribution of burst start times is uniform within its spin phase for both Insight-HXMT and Fermi/GBM observations, whereas the phase distribution of burst photons is related to the type of a burst’s energy spectrum. The bursts with the same spectrum have different distribution characteristics in the initial and decay episodes for the activity of magnetar SGR J1935+2154.
Effects of long-term annealing-induced microstructure evolution on mechanical performance and deuterium release behavior of Li4SiO4 pebbles
Authors: Gu S. , Ji B. , Wang C. , Qi Q. , Zhou H.-S. , Zhang Y. , Luo G.-N. 
Published: January 2023

Abstract
Lithium-based ceramic breeder Li4SiO4 will suffer long-term high temperature during operation. That may lead to changes to its microstructure, chemical phase, composition elements, and further impacts its mechanical performance and hydrogen isotope release behavior. In the present work, long-term annealing at 900 °C in He incl. 0.1 vol% H2 flow atmosphere for designated times was conducted. Li4SiO4 pebbles with poor or excellent mechanical performance (abbr. “poor pebbles” and “excellent pebbles”) have porous or dense microstructure, respectively. Coarsening process that grains and pores get larger as a function of annealing time was observed for Li4SiO4 poor pebbles. Li4SiO4 excellent pebbles can maintain its microstructure stability, and only slight grain growth was observed after 1000 h of annealing. Oxygen and lithium element loss was demonstrated over annealing time. Compression tests and Weibull analysis indicate that the distinct degradation of mechanical performance of Li4SiO4 pebbles mainly occur in the initial 100 h of annealing, and then the degradation process slows down. Thermal desorption spectroscopy reveals that 1000 h of annealing caused the disappearance of high temperature release peak (665 °C) and the shift of low temperature release peaks (around 300 °C) to lower temperature. The former is mainly attributed to decomposition of carbon impurities (Li2CO3) and the latter is attributed to carbon impurities and the transition from closed to open pores.
Mapping electric vehicle impacts: greenhouse gas emissions, fuel costs, and energy justice in the United States
Authors: Vega-Perkins Jesse , Newell Joshua P , Keoleian Gregory 
Published: January 2023

Abstract
The transition to electric vehicles (EVs) will impact the climate, the environment, and society in highly significant ways. This study compares EVs to vehicles with internal combustion engines for three major areas: greenhouse gas emissions (GHGs), fuel costs, and transportation energy burden (i.e. percentage of income spent on vehicle fuels). Excluded in the analysis is the purchase cost of the vehicles themselves. The results reveal that over 90% of vehicle-owning U.S. households would see reductions in both GHGs and transportation energy burden by adopting an EV. For 60% of households these savings would be moderate to high (i.e. >2.3 metric tons of CO2e reduction per household annually and >0.6% of energy burden reduction). These reductions are especially pronounced in the American West (e.g. California, Washington) and parts of the Northeast (e.g. New York) primarily due to a varying combination of cleaner electricity grids, lower electricity prices (relative to gas prices), and smaller drive-cycle and temperature-related impacts on fuel efficiency. Moreover, adopting an EV would more than double the percentage of households that enjoy a low transportation energy burden (<2% of income spent on fuel annually). This equates to 80% of all vehicle-owning U.S. households. Nevertheless, over half of the lowest income households would still have a high EV energy burden (>4% income spent on fuel annually), and if at-home charging is unavailable, this rises to over 75 percent. Addressing this inequity hinges on three major interventions: 1) targeted policies to promote energy justice in lower-income communities, including subsidizing charging infrastructure; 2) strategies to reduce electricity costs; and 3) expanding access to low-carbon transport infrastructure (e.g. public transit, biking, and car sharing).
Younger facial looks are associate with a lower likelihood of several age-related morbidities in the middle-aged to elderly
Authors: Mekić Selma , Pardo Luba M , Gunn David A , Jacobs Leonie C , Hamer Merel A , Ikram M Arfan , Vinke Eline J , Vernooij Meike W , Haarman Annet E G , Thee Eric F , Vergroesen Joelle E , Klaver Caroline C W , Croll Pauline H , Goedegebure Andre , Trajanoska Katerina , Rivadeneira Fernando , van Meurs Joyce B J , Arshi Banafsheh , Kavousi Maryam , de Roos Emmely W , Brusselle Guy G O , Kayser Manfred  , Nijsten Tamar 
Published: January 2023

Abstract

Background
Looking older for one’s chronological age is associated with a higher mortality rate. Yet it remains unclear how perceived facial age relates to morbidity and the degree to which facial ageing reflects systemic ageing of the human body.

Objectives
To investigate the association between ΔPA and age-related morbidities of different organ systems, where ΔPA represents the difference between perceived age (PA) and chronological age.

Methods
We performed a cross-sectional analysis on data from the Rotterdam Study, a population-based cohort study in the Netherlands. High-resolution facial photographs of 2679 men and women aged 51.5–87.8 years of European descent were used to assess PA. PA was estimated and scored in 5-year categories using these photographs by a panel of men and women who were blinded for chronological age and medical history. A linear mixed model was used to generate the mean PAs. The difference between the mean PA and chronological age was calculated (ΔPA), where a higher (positive) ΔPA means that the person looks younger for their age and a lower (negative) ΔPA that the person looks older. ΔPA was tested as a continuous variable for association with ageing-related morbidities including cardiovascular, pulmonary, ophthalmological, neurocognitive, renal, skeletal and auditory morbidities in separate regression analyses, adjusted for age and sex (model 1) and additionally for body mass index, smoking and sun exposure (model 2).

Results
We observed 5-year higher ΔPA (i.e. looking younger by 5 years for one’s age) to be associated with less osteoporosis [odds ratio (OR) 0.76, 95% confidence interval (CI) 0.62–0.93], less chronic obstructive pulmonary disease (OR 0.85, 95% CI 0.77–0.95), less age-related hearing loss (model 2; B = −0.76, 95% CI −1.35 to −0.17) and fewer cataracts (OR 0.84, 95% CI 0.73–0.97), but with better global cognitive functioning (g-factor; model 2; B = 0.07, 95% CI 0.04–0.10).

Conclusions
PA is associated with multiple morbidities and better cognitive function, suggesting that systemic ageing and cognitive ageing are, to an extent, externally visible in the human face.
Management of patients with hidradenitis suppurativa having underlying genetic variation: a systematic review and a call for precision medicine
Authors: Mintoff Dillon , Pace Nikolai P , Borg Isabella 
Published: January 2023

Abstract
Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the pilosebaceous unit characterized by inflammation and hyperkeratinization. A small but significant proportion of patients with HS have a strong genetic susceptibility to (or a syndromic form of) the disease. Current HS treatment guidelines prioritize patients who manifest classic HS and may therefore not be suitable for the minority of patients harbouring genetically driven forms of disease. In this manuscript, we review the extant literature with regards to therapeutic strategies used for patients with HS having disease-associated genetic variants and syndromic forms of the condition. The findings of this review suggest that patients with HS harbouring underlying genetic variants may not be adequately represented in current European and British HS treatment guidelines. Moreover, these patients may be less responsive to the recommended therapeutic options. We therefore make recommendations for future therapeutic guidelines to incorporate considerations for the management of this patient subset.
Review of dermatofibrosarcoma protuberans
Authors: Lim Su X , Ramaiya Arjun , Levell Nick J , Venables Zoe C 
Published: January 2023

Abstract
The clinical features, histological subtypes and management of dermatofibrosarcoma protuberans (DFSP) are reviewed in this article. DFSP is an uncommon cutaneous sarcoma first described in 1890. It has a high local recurrence rate, low metastatic rate and low mortality. The crude incidence rate in England in 2019 was reported as 3.0 per million person-years. A fusion of platelet-derived growth factor subunit B (PDGFB) and COL1A1, t(17;22)(q22;q13), has been found in over 90% of people with DFSP. This fusion is thought to upregulate PDGFB expression, stimulating cell growth by activation of Ras mitogen-activated protein kinases and PI3K–AKT–mTOR, potentiating oncogenesis. DFSP usually presents as an asymptomatic flesh-coloured, thickened, rubbery plaque or nodule with an uneven surface. The most common sites are the trunk followed by lower limbs, head and neck and upper limbs. Larger tumours can infiltrate underlying local structures and around 1% metastasize. Key histological features in DFSP are spindle cells arranged in a storiform pattern with intense CD34 staining. Histological subtypes include classical DFSP, Bednar, myxoid, giant cell fibroblastoma, atrophic and DFSP–fibrosarcomatous. The gold standard management for localized tumours is surgical: current recommendations favour Mohs micrographic surgery over wide local excision. Adjuvant radiotherapy may be offered after surgery. Imatinib can be used as neoadjuvant therapy and in patients with inoperable or metastatic tumours. Further research should be conducted to better understand pathogenesis of DFSP, identify associated risk factors and standardize management.
Individual-level functional connectomes predict the motor symptoms of Parkinson’s disease
Authors: Shi Zhongyan , Jiang Bo , Liu Tiantian , Wang Li , Pei Guangying , Suo Dingjie , Zhang Jian , Funahashi Shintaro , Wu Jinglong , Yan Tianyi 
Published: January 2023

Abstract
Abnormalities in functional connectivity networks are associated with sensorimotor networks in Parkinson’s disease (PD) based on group-level mapping studies, but these results are controversial. Using individual-level cortical segmentation to construct individual brain atlases can supplement the individual information covered by group-level cortical segmentation. Functional connectivity analyses at the individual level are helpful for obtaining clinically useful markers and predicting treatment response. Based on the functional connectivity of individualized regions of interest, a support vector regression model was trained to estimate the severity of motor symptoms for each subject, and a correlation analysis between the estimated scores and clinical symptom scores was performed. Forty-six PD patients aged 50–75 years were included from the Parkinson’s Progression Markers Initiative database, and 63 PD patients were included from the Beijing Rehabilitation Hospital database. Only patients below Hoehn and Yahr stage III were included. The analysis showed that the severity of motor symptoms could be estimated by the individualized functional connectivity between the visual network and sensorimotor network in early-stage disease. The results reveal individual-level connectivity biomarkers related to motor symptoms and emphasize the importance of individual differences in the prediction of the treatment response of PD.
Dissociable salience and default mode network modulation in generalized anxiety disorder: a connectome-wide association study
Authors: Li Rong , Shen Fei , Sun Xiyue , Zou Ting , Li Liyuan , Wang Xuyang , Deng Chijun , Duan Xujun , He Zongling , Yang Mi , Li Zezhi , Chen Huafu 
Published: January 2023

Abstract
Generalized anxiety disorder (GAD) is a common anxiety disorder experiencing psychological and somatic symptoms. Here, we explored the link between the individual variation in functional connectome and anxiety symptoms, especially psychological and somatic dimensions, which remains unknown. In a sample of 118 GAD patients and matched 85 healthy controls (HCs), we used multivariate distance-based matrix regression to examine the relationship between resting-state functional connectivity (FC) and the severity of anxiety. We identified multiple hub regions belonging to salience network (SN) and default mode network (DMN) where dysconnectivity associated with anxiety symptoms (P &lt; 0.05, false discovery rate [FDR]-corrected). Follow-up analyses revealed that patient’s psychological anxiety was dominated by the hyper-connectivity within DMN, whereas the somatic anxiety could be modulated by hyper-connectivity within SN and DMN. Moreover, hypo-connectivity between SN and DMN were related to both anxiety dimensions. Furthermore, GAD patients showed significant network-level FC changes compared with HCs (P &lt; 0.01, FDR-corrected). Finally, we found the connectivity of DMN could predict the individual psychological symptom in an independent GAD sample. Together, our work emphasizes the potential dissociable roles of SN and DMN in the pathophysiology of GAD’s anxiety symptoms, which may be crucial in providing a promising neuroimaging biomarker for novel personalized treatment strategies.
Cortical thickness, gray matter volume, and cognitive performance: a crosssectional study of the moderating effects of age on their interrelationships
Authors: de Chastelaine Marianne , Srokova Sabina , Hou Mingzhu , Kidwai Ambereen , Kafafi Seham S , Racenstein Melanie L , Rugg Michael D 
Published: January 2023

Abstract
In a sample comprising younger, middle-aged, and older cognitively healthy adults (N = 375), we examined associations between mean cortical thickness, gray matter volume (GMV), and performance in 4 cognitive domains—memory, speed, fluency, and crystallized intelligence. In almost all cases, the associations were moderated significantly by age, with the strongest associations in the older age group. An exception to this pattern was identified in a younger adult subgroup aged &lt;23 years when a negative association between cognitive performance and cortical thickness was identified. Other than for speed, all associations between structural metrics and performance in specific cognitive domains were fully mediated by mean cognitive ability. Cortical thickness and GMV explained unique fractions of the variance in mean cognitive ability, speed, and fluency. In no case, however, did the amount of variance jointly explained by the 2 metrics exceed 7% of the total variance. These findings suggest that cortical thickness and GMV are distinct correlates of domain-general cognitive ability, that the strength and, for cortical thickness, the direction of these associations are moderated by age, and that these structural metrics offer only limited insights into the determinants of individual differences in cognitive performance across the adult lifespan.
US–China Economic Rivalry and the Reshoring of Global Supply Chains
Authors: Gur Nurullah , Dilek Serif 
Published: January 2023

Abstract
Since the Global Financial Crisis (GFC) of 2008, the USA has changed its economic priorities and policy preferences in a concerted effort to bolster its weight in the global economy, reduce over-reliance on global supply chains, and create more employment within its borders. This change has become more apparent in the wake of the Trump presidency and the COVID-19 pandemic. Reviving the manufacturing industry through reshoring is now the main goal of US politicians. This article analyses the two strategies, in light of heightened technological competition with China, that the USA has brought into effect to reshore its factories from the People's Republic of China and so revitalise the American manufacturing industry. They are neo-protectionism and smart automation. Arguing that neo-protectionist policies and smart automation technologies are interrelated factors that have been used strategically to bring American multinational companies in China back to the USA, we examine whether or not these two strategies—each elements of the US–China tech war—can support the reshoring and revitalisation of the American manufacturing industry. We find that increased neo-protectionist measures and proliferation of smart automation technologies alone will not empower the USA sufficiently to consolidate its technological superiority over China, add impetus to its manufacturing investments, and create well-paying jobs for the broader segments of American society through the reshoring of manufacturing activities. To achieve these goals, the USA should instead implement an integrated policy framework that spans industrial policies to technology policies and tax policies to labour market policies. Otherwise, even though reshoring may gain a certain momentum, new industrial facilities will not expand productivity enough to raise the competitiveness of the US economy to satisfactory levels, and such investments might not provide enough new job opportunities to remediate socioeconomic problems.
Masking the Strangulation of Opposition Parties as Pandemic Response: Austerity Measures Targeting the Local Level in Hungary
Authors: Kovarek Daniel , Dobos Gábor 
Published: January 2023

AbstractWhile a large literature studies the various tools of autocratic survival, targeting opposition actors with austerity measures in electoral autocracies is hitherto understudied. This paper argues that the COVID-19 pandemic has provided a rare opportunity for Hungary’s Fidesz party to disarm opposition parties via cutting off resources of municipalities led by opposition mayors and eliminating any remnants of local governments’ fiscal autonomy. Analysing original data from government decrees on local transfers, this study contributes to the existing literature by conceptualising fiscal strangulation as part of electoral authoritarian regimes’ toolbox to discredit opposition parties and their ability to govern locally.