bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytical performance of the FDA-cleared Parsortix® PC1 system
Authors: Templeman Amy , Miller M. Craig , Cooke Martin J. , O'Shannessy Daniel J. , Gurung Yuwaraj , Pereira Tiago , Peters Samuel G. , De Piano Mario , Teo Manilyn , Khazan Negar , Kim Kyukwang , Cohen Evan , Lopez Heather B. , Alvarez Franklin , Ciccioli Mariacristina , Pailhes-Jimenez Anne-Sophie 
Published: September 2023

Introduction: The Parsortix® PC1 system, Food and Drug Administration (FDA) cleared for use in metastatic breast cancer (MBC) patients, is an epitope-independent microfluidic device for the capture and harvest of circulating tumor cells from whole blood based on cell size and deformability. This report details the analytical characterization of linearity, detection limit, precision, and reproducibility for this device.
Methods: System performance was determined using K2-EDTA blood samples collected from self-declared healthy female volunteers (HVs) and MBC patients spiked with prelabeled cultured breast cancer cell lines (SKBR3, MCF7, or Hs578T). Samples were processed on Parsortix® PC1 systems and captured cells were harvested and enumerated.
Results: The system captured and harvested live SKBR3, MCF7, and Hs578T cells and fixed SKBR3 cells linearly between 2 and ~100 cells, with average harvest rates of 69%, 73%, 79%, and 90%, respectively. To harvest ≥1 cell ≥95% of the time, the system required 3, 5 or 4 live SKBR3, MCF7 or Hs578T cells, respectively. Average harvest rates from precision studies using 5, 10, and ~50 live cells spiked into blood for each cell line ranged from 63.5% to 76.2%, with repeatability and reproducibility percent coefficient of variation (%CV) estimates ranging from 12.3% to 32.4% and 13.3% to 34.1%, respectively. Average harvest rates using ~20 fixed SKBR3 cells spiked into HV and MBC patient blood samples were 75.0% ± 16.1% (%CV = 22.3%) and 68.4% ± 14.3% (%CV = 21.1%), respectively.
Conclusions: These evaluations demonstrate the Parsortix® PC1 system linearly and reproducibly harvests tumor cells from blood over a range of 1 to ~100 cells.
Menopoz Eş Desteği Ölçeği’ni Türkçe’ye Uyarlama Çalışması: Menopozda Eş Desteği
Authors: TESKERECİ Gamze , SÜMEN Adem 
Published: September 2023

Amaç: Bu çalışma, Menopoz Eş Desteği Ölçeği’nin (MEDÖ) Türk kültüründe geçerlik ve güvenirliğini test etmek amacıyla yapılmıştır.
Gereç ve Yöntemler: Çalışma metodolojik tipte gerçekleşmiştir. Araştırmada olasılıksız örnekleme yöntemlerinden amaçlı örnekleme yöntemi kullanılmıştır. Çalışmaya Türkiye’nin güneyinde yer alan bir ilçedeki 45-65 yaş arası toplam 335 kadın katılmıştır. Araştırma verileri Kişisel Bilgi Formu ve Menopoz Eş Desteği Ölçeği kullanılarak, yüz yüze toplanmıştır. MEDÖ’nün psikometrik özelliklerini tespit etmek için kapsam ve yapı geçerliği ve iç tutarlık güvenirliği analiz yöntemlerinden yararlanılmıştır.
Bulgular: MEDÖ’nün 17 maddelik Türkçe formuna uygulanan açıklayıcı faktör analizi sonucuna göre dört boyutlu olduğu doğrulanmıştır. Faktör yükleri 0,553-0,881 arasında değişmektedir. Doğrulayıcı faktör analizine göre modelin, CFI, NFI değerleri bakımından iyi uyuma; χ2/sd, GFI, TLI, RMSEA değerleri bakımından kabul edilebilir uyuma sahip olduğu görülmüştür. Ölçeğin tümü için Cronbach Alfa katsayısı toplamda 0,958, alt boyutlarında ise 0,844-0,927 olarak bulunmuştur. Katılımcıların MEDÖ toplam puan ortalaması 102,03±37,54 ve ölçek alt boyut puanları arasındaki pearson korelasyon katsayısı 0,534-0,850 arasındadır.
Sonuç: Türk kültürüne uyarlanan MEDÖ menopozdaki kadınların eş desteğini belirlemede geçerli ve güvenilir bir ölçme aracıdır. Ölçek, hemşireler ve diğer sağlık hizmeti sunucuları tarafından birinci veya ikinci basamak sağlık hizmetlerinde, toplum çalışmalarında, menopoz dönemindeki kadınlara yönelik müdahale programlarında, bilimsel araştırmalarda ve eşten hangi tür destekleyici davranışların gerekli olduğunu belirlemede kullanılabilir.
Bariatrik Cerrahi Hastalarının Sağlıklı Yeme İndeksi ile Diyet Kalitelerinin Değerlendirilmesi
Authors: IŞIK Yasin , ERDEM Nihal Zekiye , SEVEN AVUK Hande , DEMİREL Birsen 
Published: September 2023

Amaç: Bu çalışmada, Sağlıklı Yeme İndeksi (SYİ) ile bariatrik cerrahi hastalarında diyet kalitelerinin değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Araştırma Kasım 2018 – Mart 2019 tarihlerinde Sleeve Gastrektomili (SG), en az 3 ayını doldurmuş, toplam 44 (%75’i kadın, %25’i erkek) gönüllü birey üzerinde 40 sorudan oluşan anket formu ile yüz yüze görüşme yöntemiyle yapılmıştır. Bireylerin diyet kaliteleri Sağlıklı Yeme İndeksi-2010 ile değerlendirilmiştir.
Bulgular: SYİ toplam puan ortalaması 62,15±6,13’tür ve cinsiyetler arasında farklılık görülmemiştir (p=0,586). SYİ alt gruplarına göre süt, protein ve sebze, meyve grubu yiyecekleri yüksek diyet kalitesinde ve tam tahıllı yiyecekleri ise düşük diyet kalitesinde tükettikleri saptanmıştır. Cerrahi sonrasında beslenme desteği alanların diyet kalitesinde toplam sebze puan ortancası, beslenme desteği almayanlardan daha yüksek; yağ asitleri puanı ise daha düşük bulunmuştur (p=0,038, p=0,019). Kadınların günlük enerji alım ortalaması 963,2±134 kkal, protein alımı 45,2±9,1 g iken erkeklerin sırasıyla 1049,8±121,5 kkal ve 53,5±5,3 g olarak bulunmuştur. Erkek bireylerin günlük protein alım miktarı kadınlardan istatistiksel olarak önemli fazla saptanmıştır (p=0,007). Her iki cinsiyette folat, D vitamini ve tiamin günlük alımının yetersiz olduğu saptanmıştır. Günlük kalsiyum, folat, sodyum alım düzeyinin erkeklerde; çinko alım düzeyinin ise kadınlarda daha fazla olduğu belirlenmiştir (p
İşitme Engelli ve Normal Gelişim Gösteren Çocuklara Sahip Ailelerin Sosyal Destek, Yılmazlık ve Tükenmişlik Düzeylerinin İncelenmesi
Authors: NAZİK Ayşenur , DOĞAN Özcan , PALANCI Mehmet 
Published: September 2023

Amaç: Yapılan araştırma işitme engelli ve normal gelişim gösteren çocuklara sahip ailelerde sosyal destek, tükenmişlik ve yılmazlık düzeylerinin karşılaştırmalı incelenmesi amacıyla yürütülmüştür.
Gereç ve Yöntemler: Özel eğitim gerektiren çocuklara sahip olmak travmatik stres bozukluğu, duygu durumuna ilişkin sorunlar ve evlilik sürecine ilişkin yaşam sorunları üretebilmektedir. Bu yaşantılara neden olabilecek aracı değişkenlerin tür, düzey ve ilişkilerinin ortaya konulması çocuk gelişim süreci ve ailelere sağlanacak çok yönlü destek için destek sağlayacaktır. Bu amaçlara erişmek için kurgulanan araştırmada her iki gruba düşen ebeveynlere Yenilenmiş Anne-Baba Sosyal Destek Ölçeği (YABSDÖ), Aile Yılmazlık Ölçeği (AYÖ) ve Maslach Tükenmişlik Ölçeği (MTÖ) uygulanmıştır. Araştırıma grubunu Samsun, Trabzon, Ordu, Rize ve Ankara il merkezlerinde yaşayan takvim yaşı 5-17 arası olan, işitme engeli olan ve normal gelişim gösteren çocukların aileleri oluşturmuştur. Araştırma grubunu 315 anne baba oluşturmaktadır. İstatistiksel hesaplamalarda iki grup arasındaki karşılaştırma için t testi, ailelerin yılmazlık düzeylerini sosyal destek ve tükenme düzeyi ile ortak bir model içerisinde yordamak içinse korelasyon ve aşamalı regresyon analizinden yararlanılmıştır.
Bulgular: Araştırma sonuçları, işitme engelli ve normal gelişim gösteren çocuğa sahip ebeveynlerin sosyal destek (YABSDÖ), yılmazlık (AYÖ) ve tükenmişlik (MTÖ) puanlarının anlamlı düzeyde farklılık gösterdiğini; işitme engelli çocuğa sahip ebeveynlerin normal gelişim gösteren çocuğa sahip ebeveynlere kıyasla sosyal destek ve yılmazlık düzeylerinin anlamlı ölçüde daha düşük, tükenmişlik düzeylerinin anlamlı ölçüde daha yüksek olduğunu göstermektedir.
Sonuç: İşitme engelli olan ve normal gelişim gösteren çocuğa sahip ailelerin yılmazlık düzeylerini yordamak için gerçekleştirilen aşamalı regresyon analizinde sosyal destek ve tükenmişlik değişkenlerinin yılmazlık için anlamlı bir yordayıcı olduğu ortaya koyulmuştur.
Dr. Ersin Arslan Eğitim ve Araştırma Hastanesi Mikrobiyoloji Laboratuvarı’nda 2016-2022 Yılları Arasında Saptanan Bağırsak Parazitlerinin Dağılımı; Pandemi Öncesi ve Sonrası Değerlendirme
Authors: ÖZKEKLİKÇİ Ahmet , CİRİT Osman Sezer 
Published: September 2023

Amaç: Bu çalışmada, Gaziantep Dr. Ersin Arslan Eğitim ve Araştırma Hastanesi mikrobiyoloji laboratuvarına 1 Ocak 2016-31 Aralık 2022 tarihleri arasında çeşitli gastrointestinal şikayetlerle başvuran hastaların dışkı örneği incelenmiştir. Bağırsak parazitlerinin yıllar içindeki dağılımı ve COVID-19 pandemisinin parazit dağılımına etkisinin araştırılması amaçlanmıştır.
Gereç ve Yöntemler: Çalışmada 15107 dışkı ve 164 selofan bant örneğinin sonuçları retrospektif olarak araştırıldı. Makroskobik incelemeden sonra nativ-lugol ve tuzlu su yüzdürme yöntemleriyle 100’lük ve 400’lük büyütmelerde dışkı örnekleri incelendi. Entamoeba histolytica veya şüpheli protozoon içeren örnekler ise trikrom boyama yöntemi ile incelendi.
Bulgular: Toplam1673 dışkı örneğinde bir veya birden fazla parazit saptanmıştır. Erkek hastaların (n=875) %10,54’ünde, kadın hastaların (n=798) %11,73’ünde parazit saptanmıştır. En sık rastlanan parazit %4,67 (n=712) Blastocystis hominis olarak tespit edilmiştir. Parazit saptanan olguların 369’unda (%2,42) Entamoeba coli, 215’inde (%1,41) Giardia intestinalis, 182’sinde (%1,19) E. histolytica/dispar olduğu tespit edilmiştir. Pozitif saptadığımız dışkı örneklerinin 139’unda (%8,3) birden fazla parazit bir arada görülmüş olup, en sık E. histolytica/dispar-B. hominis birlikteliği saptanmıştır. Toplam 164 selofan bant örneğinin 32’sinde (%19,51) helmint yumurtası saptanmıştır (19’u Enterobius vermicularis, 13’ü Taenia spp. yumurtası). Yıllara göre parazit görülme oranı incelendiğinde 2016’da %13,77 olan oranın 2022’de %8,36’ya düştüğü tespit edilmiştir.
Sonuç: Sosyoekonomik alanlardaki gelişmelere ve yerel yönetimlerin sanitasyon alanlarındaki yatırımlarına rağmen paraziter hastalıklar ilimizde önemli bir halk sağlığı sorunu olarak varlığını göstermektedir.
The Effect of Probiotic Consumption Status and Quality of Life in Patients with Fibromyalgia
Authors: CELİK YALCİN Seher , PASİN Tuğçe , ANKARALİ Seyit 
Published: September 2023

Aim: Recent studies have suggested that disruptions in the gut microbiota could potentially contribute to the pathogenesis of chronic pain and fibromyalgia syndrome (FMS) by affecting the gut microbiota-brain axis. The increasing prevalence of fibromyalgia syndrome has prompted investigations into the impact of probiotic food consumption, which regulates the microbiota, on quality of life.
Material and Methods: The study included 99 patients diagnosed with fibromyalgia syndrome who presented to our Physical Medicine and Rehabilitation outpatient clinic. A questionnaire was administered to assess the patients' knowledge and consumption of probiotic foods, and the Short Form-12 Health Survey(SF-12) was used to gather data and assess health-related quality of life.
Results: Of the 99 patients who completed the questionnaire, 89 were female and 10 were male. In response to the question, "Do you know what probiotics are?"7.4% of primary school graduates,64.7% of high school graduates, and 78.6% of university graduates answered affirmatively. When asked, "Have you experienced any benefits from probiotic foods?" 21.2% responded positively, and among those who experienced benefits, the most common accompanying issue (37.04%) was Irritable Bowel Syndrome(IBS). Fibromyalgia syndrome patients who consumed yogurt as a probiotic had higher physical function subdomain scores on the SF-12 Health Survey.
Conclusion: The high level of education in FMS patients increased the awareness of probiotics. Probiotic consumption may have a improving effect on irritable bowel syndrome and constipation associated with FMS.Training on probiotics and increasing the frequency of use of probiotics, the quality of life of FMS patients can be increased and accompanying symptoms can be reduced.
HAMBATAN KOMUNIKASI INTERAKSIONAL PADA DPAC PDIP DI KECAMATAN BATU AJI KOTA BATAM
Authors: Muarif Dwi Safitri Rahmadani 
Published: September 2023

Indonesia is a country that uses a democratic system, so political communication is one of the main keys to the establishment of politics in this democratic country. Communication can be in the form of conveying information to the public by political party candidates to convey their goals to become a politician. Political communication is also intended as a vessel for channeling people's aspirations to prospective political members who will advance as power holders in a democratic country like Indonesia. Therefore the purpose of this study is to find out how the communication barriers that occur in the Batu Aji sub-district community are carried out by the Indonesian Democratic Party of Struggle and to find out what causes the delay in the political communication process. This study used descriptive research with qualitative research methods located in Batu Aji District. Data collection techniques used were observation and interview techniques and continued with documentation. The results of the discussion obtained are that the success achieved by political actors depends on how political communication goes well and smoothly without any obstacles, by building relationships with the community and building trust so that there is no miscommunication that occurs in politics.

Keywords: Obstacles, Politic, Communication, Democratic
Medial opening-wedge high tibial osteotomy with microfracture in treatment of varus medial compartmental knee osteoarthritis: clinical outcomes and second-look arthroscopic results
Authors: Bai Yunpeng , Lin Binhui , Wang Miao , Ding Haoliang , Sun Weibing , Sun Jian 
Published: September 2023

Objective: This study aimed to investigate the clinical outcomes of medial opening high tibial osteotomy (MOWHTO) combined with arthroscopic microfracture in the treatment of varus medial compartmental knee osteoarthritis and to assess cartilage regeneration using second-look arthroscopy.Methods: This study involved 86 patients (86 knees) who underwent MOWHTO and microfracture from August 2016 to August 2020, including 15 men and 71 women with an average age of 55.3 ± 7.6 years (range, 42–71 years). The patients underwent a second-look arthroscopy to evaluate the status of cartilage regeneration at the time of plate removal, an average of 2 years after the initial osteotomy. Clinical and radiological examinations were performed preoperatively and at the final follow-up visit. The radiologic evaluation included the weight-bearing line ratio (WBL ratio), mechanical femorotibial angle (FTA), medial proximal tibial angle (MPTA), posterior tibial slope angle (PTS) and Kellgren-Lawrence (KL) grade. Clinical outcomes were assessed using the Knee Society score (KSS) and International Knee Documentation Committee (IKDC) scores. Arthroscopic findings were assessed by macroscopic evaluation of cartilage repair according to the International Cartilage Repair Society (ICRS) grading system.Results: The mean KSS and IKDC scores significantly improved at the final follow-up compared to the scores obtained preoperatively (p &lt; 0.05). At the time of plate removal, a second-look arthroscopic examination showed that the ICRS grade of the medial femoral condyle was as follows: grade I −11 cases, grade II -56, grade III-12, and grade IV-7, and cartilage regeneration was seen in 85% of knees (73/86). The ICRS grade of medial tibial plateau was grade I-12 cases, grade II-44, grade III-22, and grade IV-8, and cartilage regeneration was seen in 63% of knees (54/86). Significant differences were observed between cartilage regeneration and clinical outcomes (p &lt; 0.05). Clinical results were better in the good cartilage regeneration group (grades I and II) than were in the poor cartilage regeneration group (grades III and IV).Conclusion: MOWHTO combined with arthroscopic microfracture can effectively improve clinical outcomes in the treatment of varus medial compartmental knee osteoarthritis. Cartilage regeneration can be promoted by correcting varus deformities, which affect clinical outcomes.
Role of lamp type in conventional batch and micro-photoreactor for photocatalytic hydrogen production
Authors: Meinhardová Vendula , Dubnová Lada , Drobná Helena , Matějová Lenka , Kočí Kamila , Čapek Libor 
Published: September 2023

The use of an irradiation source with a homogeneous distribution of irradiation in the volume of the reaction mixture belongs to the essential aspects of heterogeneous photocatalysis. First, the efficacy of six lamps with various radiation intensity and distribution characteristics is contrasted. The topic of discussion is the photocatalytic hydrogen production from a methanol-water solution in the presence of a NiO-TiO2 photocatalyst. The second section is focused on the potential of a micro-photoreactor system–the batch reactor with a micro-reactor with a circulating reaction mixture, in which the photocatalytic reaction takes place using TiO2 immobilized on borosilicate glass. Continuous photocatalytic hydrogen generation from a methanol-water solution is possible in a micro-photoreactor. This system produced 333.7 ± 21.1 µmol H2 (252.8 ± 16.0 mmol.m−2, the hydrogen formation per thin film area) in a reproducible manner during 168 h.
Analysis of genetic variability in Turner syndrome linked to long-term clinical features
Authors: Suntharalingham Jenifer P. , Ishida Miho , Cameron-Pimblett Antoinette , McGlacken-Byrne Sinead M. , Buonocore Federica , del Valle Ignacio , Madhan Gaganjit Kaur , Brooks Tony , Conway Gerard S. , Achermann John C. 
Published: September 2023

BackgroundWomen with Turner syndrome (TS) (45,X and related karyotypes) have an increased prevalence of conditions such as diabetes mellitus, obesity, hypothyroidism, autoimmunity, hypertension, and congenital cardiovascular anomalies (CCA). Whilst the risk of developing these co-morbidities may be partly related to haploinsufficiency of key genes on the X chromosome, other mechanisms may be involved. Improving our understanding of underlying processes is important to develop personalized approaches to management.ObjectiveWe investigated whether: 1) global genetic variability differs in women with TS, which might contribute to co-morbidities; 2) common variants in X genes - on the background of haploinsufficiency - are associated with phenotype (a “two-hit” hypothesis); 3) the previously reported association of autosomal TIMP3 variants with CCA can be replicated.MethodsWhole exome sequencing was undertaken in leukocyte DNA from 134 adult women with TS and compared to 46,XX controls (n=23), 46,XX women with primary ovarian insufficiency (n=101), and 46,XY controls (n=11). 1) Variability in autosomal and X chromosome genes was analyzed for all individuals; 2) the relation between common X chromosome variants and the long-term phenotypes listed above was investigated in a subgroup of women with monosomy X; 3) TIMP3 variance was investigated in relation to CCA.ResultsStandard filtering identified 6,457,085 autosomal variants and 126,335 X chromosome variants for the entire cohort, whereas a somatic variant pipeline identified 16,223 autosomal and 477 X chromosome changes. 1) Overall exome variability of autosomal genes was similar in women with TS and control/comparison groups, whereas X chromosome variants were proportionate to the complement of X chromosome material; 2) when adjusted for multiple comparisons, no X chromosome gene/variants were strongly enriched in monosomy X women with key phenotypes compared to monosomy X women without these conditions, although several variants of interest emerged; 3) an association between TIMP3 22:32857305:C-T and CCA was found (CCA 13.6%; non-CCA 3.4%, p&lt;0.02).ConclusionsWomen with TS do not have an excess of genetic variability in exome analysis. No obvious X-chromosome variants driving phenotype were found, but several possible genes/variants of interest emerged. A reported association between autosomal TIMP3 variance and congenital cardiac anomalies was replicated.
Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
Authors: Bayartai Munkh-Erdene , Luomajoki Hannu , Tringali Gabriella , De Micheli Roberta , Grugni Graziano , Sartorio Alessandro 
Published: September 2023

IntroductionSpinal kinematics/motion are reported to be altered in adolescents and adults with essential obesity, while no information is available in patients with Prader-Willi syndrome so far. The aim of this study was to examine cross-sectionally the characteristics of spinal postures and mobility in 34 patients with PWS, in 35 age- and sex-matched adults with essential obesity, and in 37 normal-weight individuals.MethodsSpinal posture and mobility were assessed using a radiation-free back scan, the Idiag M360 (Idiag, Fehraltorf, Switzerland). Differences in spinal posture and mobility between the three groups were determined using a two-way analysis of variance.ResultsAdults with Prader-Willi syndrome had greater thoracic kyphosis [difference between groups (Δ) = 9.60, 95% CI 3.30 to 15.60, p = 0.001], less lumbar lordosis (Δ = -6.50, 95% CI -12.70 to -0.30, p = 0.03) as well as smaller lumbar and hip mobility than those with normal weight.DiscussionAlthough the characteristics of the spine in patients with Prader-Will syndrome appear to be similar to that found in subjects with essential obesity, Prader-Willi syndrome was found to influence lumbar movements more than thoracic mobility. These results provide relevant information about the characteristics of the spine in adults with Prader-Willi syndrome to be taken into careful consideration in the management of spinal conditions. These findings also highlight the importance of considering the musculoskeletal assessment of spinal postures and approaches targeting spinal and hip flexibility in adults with Prader-Willi syndrome.
Iodine-induced thyroid dysfunction: a scientometric study and visualization analysis
Authors: Gong Boshen , Wang Xichang , Wang Chuyuan , Yang Wanyu , Shan Zhongyan , Lai Yaxin 
Published: September 2023

ObjectiveIodine is essential in thyroid hormone production. Iodine deficiency is associated with serious complications (i.e miscarriage and stillbirth), whereas excess can cause thyroid dysfunction (i.e hyperthyroidism, hypothyroidism, thyroid autoimmunity). We conducted this scientometric study to visualize hot spots and trends in iodine-induced thyroid dysfunction over past two decades. The aim of this paper was to help scholars quickly understand the development and potential trend in this field, and guide future research directions.MethodsArticles on iodine-induced thyroid dysfunction from 2000 to 2022 were retrieved from the Web of Science Core Collection (WoSCC) using the following search terms: (((((TS=(hypothyroid*)) OR TS=(hyperthyroid*)) OR TS= (“TSH deficiency”)) OR TS= (“thyroid stimulating hormone deficiency”)) AND TS=(Iodine)) NOT TS=(radioiodine). Only publications in English were selected. CiteSpace, VOSviewer, Tableau, Carrot2, and R software were used to analyze the contribution and co-occurrence relationships of different countries, institutes, keywords, references, and journals.ResultsA total of 2986 publications from 115 countries and 3412 research institutions were included. From 2000 to 2022, research on iodine-induced thyroid dysfunction progressed over a three-stage development period: initial development (2000-2009), stable development (2010-2016), and rapid development (2016-2022) period. The Journal of Clinical Endocrinology and Metabolism had the most co-citations followed and China Medical University (n=76) had the most publications. The top three clusters of co-citation references were isolated maternal hypothyroxinemia, subclinical hyperthyroidism, and brain development. Various scientific methods were applied to reveal acknowledge structure, development trend and research hotspots in iodine-induced thyroid dysfunction.ConclusionOur scientometric analysis shows that investigations related to pregnant women, epidemiology surveys, and iodine deficiency are promising topics for future iodine-induced thyroid dysfunction research and highlights the important role of iodine on thyroid function.