bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehension of conversational implicatures in L3 Mandarin
Authors: Köylü Yılmaz 
Published: January 2025

Abstract
The current research is an extension and partial replication of Köylü (2018. Comprehension of conversational implicatures in L2 English. Intercultural Pragmatics 15(3). 373–408.) and it investigates the development of conversational implicatures in third language (L3) Mandarin. More specifically, this study explores whether learners with a first language (L1) Cantonese and second language (L2) English background are able to comprehend implied meaning in L3 Mandarin. 14 L1 Cantonese L2 English L3 Mandarin participants with a high intermediate level of Mandarin proficiency took part in the study. There was also a control group of 11 native speakers of Mandarin. Quantitative results based on a 20-item audiovisual interpretation task demonstrate that the L3 learners of Mandarin were not on a par with native speakers of Mandarin in arriving at an intended implicature for the test items. A qualitative analysis of learner responses indicates that the learners’ interpretation of conversational implicatures in L3 Mandarin, although usually successful, was also characterized by repetitions, literal comprehension, and recognition of a gap between the literal and the implied meaning, as well as unintended implicatures.
Germ cell quantification in human fetal and prepubertal testis tissues: a comparison of current methodologies
Authors: Kearney Emma , Greenald David , Matilionyte Gabriele , Lane Sheila , Tharmalingam Melissa D , Davies Jill , Stukenborg Jan-Bernd , Forsyth Grace , Mitchell Rod T 
Published: January 2025

Abstract
Methods to quantify germ cell number in human immature testicular tissues are essential to evaluate the impact of chemotherapy exposures and to optimise cryopreservation protocols used in fertility preservation for prepubertal boys. Established quantification methods rely on the presence of round tubules within the tissue. However, round tubular cross sections are limited in human prepubertal testicular tissues, especially when using in vitro culture. We aimed to assess whether an alternative method of germ cell quantification would provide similar results to recently established methods, without the requirement for round tubules. Human testicular samples included fetal tissue (exposed in vitro to cisplatin, carboplatin or control) or prepubertal tissue (fresh, cryopreserved, fresh in vitro cultured or cryopreserved in vitro cultured). Immunofluorescence assessed AP2γ (gonocytes) and MAGE-A4 ((pre)spermatogonia) expression. Germ cells were quantified by tubular germ cell density (Method 1), which was compared to methods that require round tubules, including spermatogonial number per round tubular cross section (S/T) (Method 2), fertility index (Method 3) and round tubular germ cell density (Method 4). A correlation analysis between methods was performed. Method 1 is strongly and significantly correlated with Method 2 (r = 0.838, P < 0.0001; r = 0.833, P < 0.0001), Method 3 (r = 0.752, P < 0.001; r = 0.802, P < 0.0001) and Method 4 (r = 0.863, P < 0.0001; r = 0.914, P < 0.0001) for fetal and prepubertal tissues, respectively. Given that Method 1 assess tubules irrespective of shape, it may increase the total number of germ cells available for quantification, validating its use for quantification of human testicular tissue samples where the amount of tissue or presence of round tubules is limited.

Lay summary
Chemotherapy can damage cells in the testicles that are required to make sperm, often leading to infertility in males. While options to preserve fertility in adult males are available, there are no established methods for young boys. To investigate how chemotherapy damages these cells and to explore approaches to preserve fertility, we require methods to count the number of cells that can develop into sperm. Existing counting methods involve only counting some of the cells in the tissue, but in young boys, it is often necessary to count all of the cells because the amount of tissue is limited. To overcome this, we counted cells in small pieces of human fetal and prepubertal testicles using an alternative method, which allows all cells to be counted. We found similar results using our method compared to three existing methods, making our method useful for counting cells in fetal and prepubertal testicle samples.
АКТУАЛИЗАЦИЯ РЕГИОНАЛЬНЫХ ШКАЛ ПОЖАРНОЙ ОПАСНОСТИ ПО ЛЕСНЫМ РАЙОНАМ КРАСНОЯРСКОГО КРАЯ
Authors: ИВАНОВ В.А. , ИВАНОВА Г.А. , БАКШЕЕВА Е.О. 
Published: January 2025

В связи с интенсивным промышленным освоением территории Красноярского края произошли значительные перемены в растительном покрове и увеличилось количество источников огня. Вследствие изменения климата также возросло количество молниевых разрядов, являющихся основной причиной лесных пожаров на малоосвоенных северных территориях края. Разработка региональной шкалы пожарной опасности по условиям погоды вызвана тем, что существующая единая федеральная шкала пожарной опасности по условиям погоды недостаточно точно характеризует пожарную опасность лесных участков региона и не позволяет рационально регламентировать работы лесопожарных служб и маневрировать силами лесничеств и авиаотделений. На основе данных о количестве и площади лесных пожаров и о причинах их возникновения нами выполнены обобщения и анализ приуроченности пожаров и причин возникновения возгораний по лесным районам Красноярского края. Установлено, что в современных условиях территория края характеризуется увеличением пожарной активности. Ввиду сложности рельефа, разнообразия климатических и лесорастительных условий для каждого лесного района нами были построены региональные шкалы пожарной опасности по условиям погоды и проведено их сравнение с единой федеральной шкалой. Использование разработанных нами шкал пожарной опасности для лесных районов Красноярского края позволит своевременно проводить обнаружение и тушение лесных пожаров.
Due to the intensive industrial development of the territory of Krasnoyarsk Krai, significant changes have taken place in the vegetation cover and the number of fire sources has increased. Due to climate change, the number of lightning discharges, which are the main cause of forest fires in the underdeveloped northern territories of the region, has also increased. The development of a regional fire hazard scale for weather conditions is caused by the fact that the existing unified federal fire hazard scale for weather conditions does not accurately characterize the fire hazard of forest areas in the region and does not allow rationally regulating the work of forest fire services and forestry. On the basis of data on the number and area of forest fires and the causes of their occurrence, generalizations and analysis of the timing of fires and the causes of fires in the forest areas of Krasnoyarsk Krai were performed. It is revealed, that in modern conditions the area of the region is characterized by an increase in fire activity. Due to the complexity of the relief, the diversity of climatic and forest conditions for each forest area, we have constructed regional fire hazard scales for weather conditions and compared them with the unified federal scale. The use of fire hazard scales developed by us for the forest areas of the Krasnoyarsk Krai will allow timely detection and extinguishing of forest fires and, consequently, reduce damage from forest fires.
Prácticas de lectura y escritura en la formación de profesores de educación primaria
Authors: Noriega Jacob Mirián Adriana 
Published: January 2025

The main purpose of this text is to study how students in teacher training read and write, as well as the challenges they face in these practices, since this is still a pending task for educational research. In this way, this work intends to contribute to the discussion on academic literacy processes in teacher training based on two focus groups, in which 14 third-semester students of the Bachelor's Degree in Elementary Education from two Teacher Training Colleges participated, one of them directed to the rural context and the other to the urban one. The focus groups made it possible to explore what students read and write most frequently, the difficulties they have with these practices, their attitudes in relation to these processes, strategies for reading and writing, as well as possible alternatives to accompany them in the academic literacy process. The results show the importance of the accompaniment of the trainer of trainers to join their discursive community, and its close relationship for academic performance, thus showing that the teacher's role is not only to promote meaningful learning but also to facilitate dialogues.
Ζήτει, ‘cerca!’: un copista alla ricerca del lamento della Vergine (Ciclo della Passione cipriota, Vat. Pal. gr. 367)
Authors: Ghidoni Andrea 
Published: January 2025

AbstractBetween the end of the 13th century and the early decades of the following century, the manuscript now marked Vat. Pal. gr. 367 was compiled in Cyprus. On folios 33v–39v, it includes the text known today as the Cypriot Passion Cycle. The article focuses primarily on the episode of the Crucifixion (Περὶ τῆς σταυρώσεως), where the text presents some interpretative issues, including a blank space precisely where the Virgin Mary should utter her lament. How should this gap be interpreted? Beyond the nature of the threnos that should have been inserted (impossible to determine precisely), attention here is shifted to the fact that the need to insert a lament at this point could only have come from Western models.
تصويتُ الصَّوامتِ في العربيَّةِ بينَ الوصفِ النُّطقيِّ والبياناتِ الرَّقميَّةِ
Authors: المومني هاجر 
Published: January 2025

الملخص
تهدفُ هذهِ الدِّراسةُ إلى:
•	التقريبِ بينَ المفاهيمِ في وصفِ عمليَّةِ التَّصويتِ بينَ الدَّرسِ الصَّوتيِّ في التُّراثِ والدَّرسِ الصَّوتيِّ المعاصرِ.
•	الحصولِ على المعاييرِ الفيزيائيَّةِ لكلِّ صامتٍ في العربيَّةِ.
•	الوصولِ إلى تصنيفِ صوامتِ العربيَّةِ منْ حيثُ معاييرِها الفيزيائيَّةِ.
هذا البحثُ قائمٌ على المنهجِ الوصفيِّ التَّحليليّ. وبمقتضاهُ وُصِفَتِ الصَّوامتُ العربيَّةُ وصفًا نطقيًّا في الجزءِ النَّظريِّ منَ البحثِ. وقد اختيرَ للجزءِ التَّطبيقيِّ الرَّقميّ مئتانِ وستّونَ كلمةٍ، تمثِّلُ مواقعَ الصَّوامتِ السِّتَّةِ والعشرين، واستُخدِمَ البرنامج (CSL) بنطقٍ واحدٍ لأجلِ هذهِ الدِّراسةِ.
توصَّلتِ الدِّراسةُ إلى نتائجَ كلِّيَّةٍ تحقَّقَ بها الهدفُ الأساسيُّ الأوَّلُ والثَّلاثَةُ الأخرى المتفرِّعةُ عنْهُ؛ فقد توصَّلَ البحثُ إلى التَّقريبِ بينَ مفهومِ التَّصويتِ بفرعَيْهِ الهمسِ والجهرِ بينَ التَّوصيفِ التُّراثيِّ والتَّوصيفِ المعاصرِ. كما توصَّلَ إلى قياسِ كلِّ صامتٍ، وأُجريَت تصنيفًا للصَّوامتِ العربيَّةِ. وتوصَّلتِ الدِّراسةُ كذلكَ إلى الكشفِ عنْ صفاتٍ خاصَّةٍ ببعضِ الصَّوامتِ العربيَّةِ.
الكلمات المفتاحيّة: التّصويت، سعة التّصويت، الصّوامت العربيّة
Various methods affect the flexural strength of repairing the denture base
Authors: Alfahdawi Ibrahim H. 
Published: January 2025

Background: The assembly of replacement teeth to mimic natural ones remains a challenge for dentists, particularly regarding the surface characteristics of prosthetic teeth. Purpose: To evaluate various surface mechanical techniques that affect the flexural stress of a repaired denture base. Methods: Six sets (n = 10) of sixty heat-polymerized acrylic resin bar-shaped samples have been produced. Samples were divided into halves to give a 1-mm clearance, with the exception of the group under positive control (group PC). Also taken into account was a negative control group (group NC) that received no skin treatment. Other groups received a variety of surface treatments, including group Er:YAG laser therapy, group abrasion by airborne particles (APA), group APA + Laser, and group Bur grinding. All sectioned samples were repaired by auto-polymerizing acrylic resin, which was then thermocycled after surface roughness was measured with a profilometer. A global testing device conducted a three-point bending test. Results: The mean surface roughness of all study groups was considerably greater than group NC's (P<0.05). With the exception of group Bur, group PC's flexural strength was considerably greater than that of all other groups (P=0.999). The bending strength of groups Bur and Laser among all surface-treated groups was significantly greater than that of group NC (P=0.001 and P=0.015, respectively). Conclusion: All surface treatments enhanced surface roughness in comparison to the untreated group, but bur grinding and Er:YAG laser exposure also significantly raised the flexural strength of the sectioned groups. Sectioned polymethyl methacrylate’s flexural strength was significantly increased by bur grinding.
Effect of cocoa pod husk (Theobroma cacao L.) extract on alveolar socket post tooth extraction
Authors: Rahayu Yani Corvianindya , Yuwono Budi , Syafriadi Mei , Amin Muhammad Nurul , Kumala Efa Ayu Ratnaning 
Published: January 2025

Background: Cocoa pod husk (CPH) of Theobroma cacao L. contains tannins, alkaloids, saponins, and flavonoids triterpenoids that have antibacterial, anti-inflammatory, and antioxidant activities that can accelerate wound healing and alveolar bone regeneration. Purpose: This study aimed to analyze the effect of CPH extract gel on the number of fibroblasts, osteoblasts, and osteoclasts in Wistar rats’ sockets after tooth extraction. Methods: The samples used were 36 male Wistar rats divided into three groups: the negative control group (placebo gel), the positive control group (Alveogyl; Septodont, UK), and the treatment group (100 mg/ml CPH extract gel), which in each application was given for three, seven, and fourteen days on the mandibular first molar post-extraction socket. The samples were sacrificed and tissue was processed on days 4, 8, and 15. The amount of fibroblasts, osteoblasts, and osteoclasts was identified and determined by the Image J software. Results: The Mann-Whitney U analysis showed significant differences (p<0.05) between groups. Fibroblasts and osteoblasts in the treatment group were significantly higher than the control groups. Osteoclasts in the treatment group were significantly lower than the control group. Conclusion: Ethanol extract gel of CPH significantly increased fibroblasts on days 3 and 5 and osteoblasts on days 7 and 14 and decreased osteoclasts on day 14 in post-extraction socket of Wistar rats.
Expression characteristics, immune signatures, and prognostic value of the KIF family members identified across cancers
Authors: Zhang Xuewei , Zhang Yawei , Zheng Guoxing , Yang Ronghua 
Published: January 2025

Aim: The overexpression of Kinesin superfamily proteins (KIFs) has been increasingly recognized as a critical factor associated with unfavorable prognostic outcomes across a spectrum of cancers. This study aims to elucidate the multifaceted role of KIFs within the tumor immune microenvironment and explore their potential as targets for precision cancer therapy.
Methods: Utilizing comprehensive genomic datasets from the Cancer Genome Atlas and Genotype-Tissue Expression databases, we systematically analyzed KIF expression patterns and their potential oncogenic functions. To investigate the functional impact of KIF3A in hepatocellular carcinoma (HCC), we synthesized siKIF3A and transfected it into HepG2 cells, followed by a series of functional assays. Cell proliferation was meticulously evaluated using EdU incorporation, CCK8, and colony formation assays, while cell migration was assessed through scratch wound healing and Transwell migration assays. Quantitative analysis of gene and protein expression levels was performed using RT-PCR and Western blot techniques, respectively.
Results: Our findings reveal that KIFs exhibit remarkably high mutation frequencies across multiple cancer types. Furthermore, we identified significant genomic and epigenetic modifications of KIFs in various tumors, with specific oncogenic mutations in certain cancers potentially serving as regulatory mechanisms for KIFs expression. Notably, tumor-derived KIFs demonstrate a strong association with immune cell infiltration patterns, suggesting their potential as novel therapeutic targets in cancer immunotherapy. Importantly, the majority of KIF family genes show significant correlations with patient prognosis, underscoring their clinical relevance. Specifically, KIF3A emerges as a promising prognostic marker for HCC, demonstrating significantly higher expression levels in HCC tissues compared to adjacent non-cancerous tissues (P < 0.05). This overexpression strongly correlates with poor survival outcomes and established risk factors. Functional studies reveal that knockdown of KIF3A significantly inhibits the proliferation and migration capabilities of HCC cells (P < 0.05), highlighting its critical role in tumor progression. Our findings suggest that KIF3A not only serves as a valuable prognostic biomarker but also represents a potential therapeutic target for HCC patients, particularly through its involvement in tumor immune regulation mechanisms.
Conclusion: This comprehensive study provides novel insights into the role of KIFs, particularly KIF3A, in cancer biology and offers promising avenues for the development of targeted therapies in hepatocellular carcinoma. The integration of genomic analysis with functional validation underscores the potential of KIFs as both diagnostic markers and therapeutic targets in cancer management.
PERBEDAAN UKURAN GIGI MOLAR PERTAMA MAKSILA DAN KANINUS MANDIBULA PERMANEN ANTARA MAHASISWA LAKI-LAKI DAN PEREMPUAN (Tinjauan pada Mahasiswa PSKG Suku Banjar)
Authors: Rahmah Siti Aulia , Sukmana Bayu Indra , D.H Irnamanda 
Published: January 2025

ABSTRACTBackground: Natural disasters occur frequently in Indonesia. Gender identification is one of the important things in determining the identity of the victim. Gender can be identified based on the size of the teeth. Differences in tooth size are caused by differences in gender and race. Objective: To determine mean difference in the size of maxillary first molar teeth and mandibular caninus between males and females in Banjar tribe PSKG students. Methods This research is a analytic observational method. This study used 40 male and 40 female dental models that measured the mesiodistal and buccolingual width of the maxillary first molar and mandibular canine teeth using digital caliper. Results: The results of the normality test of normally distributed data, followed by an independent t-test, obtained a p value = 0.0001 <0.05 which shows that the hypothesis is accepted or there is a significant difference in the size of the mesiodistal and buccolingual teeth in the maxillary first molar and mandibular canine between male and female students of the Banjar tribe. Conclusion: There is a difference in the mesiodistal and buccolingual means of maxillary first molar and mandibular canine teeth between males and females in Banjar tribe PSKG students.Keywords: Sex identification, tooth size, mesiodistal, buccolingual, maxillary first molar, mandibular caninus ABSTRAKLatar Belakang : Bencana alam sering terjadi di Indonesia. Identifikasi jenis kelamin adalah salah satu hal penting dalam menentukan identitas korban. Jenis kelamin dapat diidentifikasi berdasarkan ukuran gigi geligi. Perbedaan ukuran gigi disebabkan oleh adanya perbedaan jenis kelamin dan ras. Tujuan: Untuk mengetahui perbedaan rerata ukuran gigi molar pertama maksila dan kaninus mandibula antara laki-laki dan perempuan pada mahasiswa PSKG suku Banjar. Metode: Penelitian ini merupakan metode observasional analitik. Penelitian ini menggunakan 40 model gigi laki-laki dan 40 model gigi perempuan yang diukur lebar mesiodistal dan bukolingual gigi molar pertama maksila dan kaninus mandibula menggunakan kaliper digital. Hasil: Hasil uji normalitas data berdistribusi normal, dilanjutkan dengan uji t-test independent didapatkan nilai p=0.0001<0.05 yang menunjukkan hipotesis diterima atau terdapat perbedaan signifikan ukuran gigi mesiodistal dan bukolingual pada gigi molar pertama maksila dan kaninus mandibula antara mahasiswa laki-laki dan perempuan suku Banjar. Kesimpulan: Terdapat perbedaan rerata ukuran gigi mesiodistal dan bukolingual pada gigi molar pertama maksila dan kaninus mandibula antara laki-laki dan perempuan pada mahasiswa PSKG suku Banjar. Kata kunci: Kaninus Mandibula, Bukolingual, Mesiodistal, Maksila, Jenis Kelamin, Ukuran Gigi.
OPTIMALISASI PENILAIAN DIRI DAN SEJAWAT DALAM MENINGKATKAN KEMAMPUAN MENDESAIN MODUL AJAR BAGI MAHASISWA CALON GURU FISIKA
Authors: Zainuddin Zainuddin , Salam Abdul , Miriam Sarah , Saifuddin Anwar Rahmat , Al Farej Ansari Rahmat , Khairiyah Nor 
Published: January 2025

Proses penyederhanaan Rencana Pelaksanaan Pembelajaran ke dalam bentuk modul ajar dalam implementasi kurikulum merdeka di sekolah masih menimbulkan banyak kendala di lapangan. Kendala ini juga dirasakan oleh mahasiswa calon guru ketika menjalani praktik mengajar di sekolah. Penelitian ini bertujuan untuk mengatasi permasalahan yang muncul sehubungan dengan pengembangan modul ajar dengan mengoptimalkan metode self dan peer assessment bagi mahasiswa calon guru fisika. Penelitian ini melibatkan seluruh mahasiswa pendidikan fisika dari Universitas Lambung Mangkurat (ULM) yang mengikuti program Asistensi Mengajar pada tahun 2023. Data penelitian diambil dari portofolio modul ajar yang dibuat oleh mahasiswa selama pelaksanaan asistensi mengajar, termasuk hasil karya mereka setelah menerapkan self dan peer assessment. Hasil analisis menunjukkan peningkatan yang signifikan dalam kemampuan mahasiswa merancang modul ajar, dengan rata-rata awal sebesar 62,0 meningkat menjadi 82,8. Jika dinyatakan dalam gain score, peningkatannya adalah sebesar 0,52 (berkategori sedang). Penelitian ini memberikan kontribusi dalam upaya terus-menerus untuk menyempurnakan implementasi Kurikulum Merdeka dan meningkatkan keterampilan pedagogis para calon pendidik Fisika, serta memberikan kontribusi berharga dalam bidang pendidikan.
Kata kunci: Mahasiswa Calon Guru Fisika, Modul Ajar, Penilaian Diri dan Sejawat.

Simplifying the Lesson Plans into Teaching Modules within implementing the Merdeka Curriculum in schools continues to encounter various challenges. Student teachers also experience these challenges during their teaching practice. This research aims to address the issues arising from the development of teaching modules by optimizing the methods of self and peer assessment for prospective Physics teachers. The study involves all Physics Education students from Universitas Lambung Mangkurat (ULM) participating in the Teaching Assistance program in 2023. Research data is derived from teaching module portfolios created by students during the teaching assistance period, including their work after implementing self and peer assessment. The analysis reveals a significant improvement in students' ability to design teaching modules, with an initial average score of 62.0, increasing to 82.8. Expressed as a gain score, this represents an improvement of 0.52 (categorized as moderate). This research contributes to the ongoing efforts to refine the implementation of the Merdeka Curriculum and enhance the pedagogical skills of future Physics educators, providing valuable insights into the field of education.
Keywords: Physics Teacher Candidates, Teaching Module, Self and Peer Assessment.