bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and psychometric appraisal of Head Nurse Research Leadership Scale
Authors: Guo Yuanli , Ma Keke , Guo Lina , Dong Xiaofang , Yang Caixia , Wang Min , Gao Huanhuan , Lv Peihua 
Published: January 2023

AbstractAimTo develop a Head Nurse Research Leadership Scale and evaluate its reliability and validity.DesignA psychometric instrument validation study was conducted in two phases.MethodsThe item tool was generated based on a literature review, semi‐structured interview and brainstorming. Twenty experts validated the content of the initial version for two rounds. Thirty‐nine clinical nurses conducted the HNRLS‐v3 to test the readability of the items in pilot study I. Items were screened based on the critical ratio, correlation coefficient analysis, Cronbach's α coefficient and factor analysis using the data collected from 265 nurses in pilot study II. A cross‐sectional survey was conducted in six hospitals to evaluate the reliability and validity between 4 January 2022 and 15 January 2022. Three hundred and sixteen nurses participated in this survey, and 60 completed the questionnaire to validate the test–retest reliability between 1 February and 6 February.ResultsA 15‐item Head Nurse Research Leadership Scale based on 5 dimensions was developed, and the content validity was satisfied. The 15 items accounted for 77.9% of the variance. Confirmatory factor analysis showed acceptable convergent validity and discriminant validity. The Cronbach's α coefficient, split‐half reliability and test–retest reliability of the scale were 0.966, 0.9633 and 0.927, respectively.
Stories of being a new nurse academic at a nursing education institution
Authors: Mutenga Linda , Downing Charlené , Kearns Irene J. 
Published: January 2023

AbstractObjectivesThe objectives of this study were to explore and discover the best moments of being a new nurse academic at nursing education institutions.AimThe purpose of this study was to define, discover and learn about the experiences of being a new nurse academic.DesignA qualitative design with inspiration from Appreciative Inquiry (AI) was used.MethodPurposive and snowball sampling was used. Data collection was done using semi‐structured individual interviews. Data were analysed using Giorgi's method. The COREQ guidance was used for reporting of this study.ResultsFour themes were identified. (1) The emphasis was their transition from clinical setting into the world of academics, which was challenging, overwhelming and exciting all at the same time. (2) Participants were fulfilled and influenced to achieve more. (3) Participants expressed what they wished for. (4) Participants shared recommendations for job security, employment and retainment of new nurse academics.
Discovery of novel (N‐aryl‐4‐methylpiperidinyl)pyrazoles: a new class of potent lepidopteran insecticides
Authors: Pahutski Thomas F. , Ahmad Omar K. , Marshall Eric A. , Joraski Kathleen , Barry James D. , Keathley Craig , Cordova Daniel , Benner Eric , Nesnow David , Christianson Laurie , Slack Rachel D. , Lahm George P. 
Published: January 2023

AbstractBACKGROUNDInsects of the order Lepidoptera are among the most destructive global pests, causing billions of dollars in damage annually. A new class of N‐arylpyrazole‐4‐methylpiperidines with potent activity on lepidopteran species has been discovered.RESULTSIn a high‐throughput insecticide screen compound 1 was identified to possess modest activity on the lepidopteran insect Plutella xylostella. Optimization of 1 to compound 42 resulted in a compound with excellent activity on Spodoptera exigua, Spodoptera frugiperda, and Helicoverpa zea with median lethal concentrations values of 2.8, 1.4, and 12.5 ppm respectively. Although the mode of action remains unknown, these compounds do not appear to work by many of the known biochemical mechanisms of insect control.CONCLUSIONN‐Arylpyrazole‐4‐methylpiperidines represent a new class of insecticides with excellent activity on a broad spectrum of lepidopteran pests. Studies to date indicate the potential for a novel mode of action; however, the target site is unknown at present. © 2023 Society of Chemical Industry.
Functional characterization of chemosensory proteins in response to artificial light treatment in Thalassodes immissaria
Authors: Yao Qiong , Liang Zhantu , Quan Linfa , Chen Bingxu 
Published: January 2023

AbstractBACKGROUNDChemosensory proteins (CSPs) play a vital role in the response to environmental stimuli in insects. However, the involvement of insect CSPs in the stress response to night‐time environmental changes has not been examined.RESULTSIn the current study, four TiCSP genes were first cloned from Thalassodes immissaria by transcriptome and RACE‐PCR techniques. TiCSPs had typical characteristics of insect CSPs, including a highly conserved four‐cysteine motif and olfactory‐specific protein D (OS‐D) or OS‐D superfamily domains. TiCSP1–4 were clustered classified within different clades in a phylogenetic analysis and were differentially expressed at all developmental stages. Under night‐time artificial light stress, the expression levels of TiCSP1 in males were significantly decreased at 24 h, and those of TiCSP2 were decreased in both adult sexes at 48 h. In a molecular docking analysis, TiCSPs showed relatively higher binding affinities with sex pheromone components than with host plant volatile molecules.CONCLUSIONTaking the reduced expression levels of TiCSPs and binding affinities into account, TiCSP1 and TiCSP2 are involved in the stress response processes of T. immissaria under light treatment. Our study supplies basic data for the evaluation of the effects of light interference control technology – an emerging physical control measure on nontarget pests of lychee orchards. © 2023 Society of Chemical Industry.
Indolizine: A Promising Framework for Developing a Diverse Array of C−H Functionalized Hybrids
Authors: Priyanka  , Rani Payal , Kiran  , Sindhu Jayant 
Published: January 2023

AbstractC−H functionalized indolizines have emerged as a modern sustainable protocol, as it offers robust applications in the field of agriculture, medicine and pharmaceutical sciences. In recent times, a number of effective methods for the C−C, C−P and C−S bond formation via C−H functionalization of indolizines have been established. The present review article provides a thorough assessment of recent developments in the C−H functionalization of indolizines. The review has been categorized based on C−C, C−P and C−S bond formation using conventional as well as non‐conventional methodologies. Moreover, the reaction mechanism has been discussed in elaborated form.
Blue Fluorescent Nitrogen‐Doped Carbon Dots for the Specific Detection of Mn2+
Authors: Li Yanrong , Li Haohao , Xu Yang 
Published: January 2023

AbstractManganese is one of vital elements related to various diseases. Nowadays, few works can specifically respond to Mn2+ alone. Hence, it is still challenging for specific detection of Mn ion. In this work, nitrogen‐doped carbon dots (N‐CDs) with blue luminescence properties was prepared using nitrated pyrene and diethylenetriamine (DETA) via one‐step solvothermal process. N‐CDs were applied as a fluorescent probe for specific detection of Mn2+ because of their high selectivity and sensitivity. No apparent fluorescence interferences can be observed with various amino acids and metal ions. The minimum concentration detected was 5 nM. The quenching mechanism maybe attributed to dynamic quenching processes. Notably, in this work, a visual early‐warning of Mn content exceeding the standard in drinking water in the light of fluorescence quenching of N‐CDs was achieved, and the practical sensing of N‐CDs which performed in environmental water samples demonstrated the detection performance of N‐CDs in real samples.
Effect of maternally derived antibodies on two commercial vaccines in changes of serum antibody titres against distemper in puppies
Authors: Shams Farzane , Pourtaghi Hadi 
Published: January 2023

AbstractBackgroundMaternally derived antibodies (MDA) have protection against canine distemper virus (CDV) in the first weeks of puppies’ life. However, MDA decreases with age. The most important and effective factor on immunization is timely vaccination. But in recent years, there were some outbreaks of CDV among puppies in Iran and this problem could be related to vaccine failure.ObjectivesThe aim of this study is to evaluate the possible effect of MDA titre on vaccines against CDV and the efficacy of two commercial vaccines by using the enzyme‐linked immunosorbent assay (ELISA).MethodsIn this regard, 24 healthy 8‐week old terrier puppies were selected and divided into three identical groups based on a randomized, double‐blind comparative trial. The control group was injected normal saline, and group A was vaccinated by the vaccine namely Biocan L (Bioveta, Czech Republic), and the group B was vaccinated by the other vaccine called Duramune Max 5 + LCI/GP (Fort Dodge Animal Health, USA). The vaccines were used for the puppies between 8 and 16 weeks of age and in every 4 weeks.ResultsThe results showed that the response of both vaccines was satisfactory, and no significant difference was observed between them. Moreover, the MDA in the control group reached an unprotective level in all puppies prior to their 14 weeks of age. In the vaccinated groups, after the second vaccine, all puppies in both groups reached protective levels.DiscussionThis is the first study on evaluation of two commercial vaccines in changes of serum antibody titres against distemper in puppies in Iran.ConclusionIt is recommended that veterinarians during consulting use the ELISA to measure antibody titres to optimize the vaccination schedule and reduce the cost of vaccination failure. This is of paramount importance for puppies.
Investigating nocturnal UAS treatments in an applied context to prevent gulls from nesting on rooftops
Authors: Pfeiffer Morgan B. , Pullins Craig K. , Beckerman Scott F. , Hoblet Joshua L. , Blackwell Bradley F. 
Published: January 2023

AbstractRing‐billed (Larus delawarensis) and herring (L. argentatus) gulls are numerous and widespread in North America. These gulls rank among the top 9 species for risk of bird‐aircraft collisions (hereafter strikes). The ubiquitous presence of gulls in urban coastal environments, including rooftop nesting behavior, are factors impacting strike risk. Our purpose was to assess gull response to a small uncrewed aircraft system (UAS) in hazing flights at night during the nest‐building phase. We hypothesized that nocturnal UAS operation, like nocturnal predator disturbance, might reduce gull numbers and, thus, strike risk to aircraft. In spring 2021, we conducted UAS treatments over target roofs at least once every hour from 2000 until 0200, weather permitting, for 15 min and over a 14‐day period for each site. The UAS flew directly above (~4 m) and then descended (~4 m/s) within 1 m of loafing gulls. No gulls interacted with the UAS and most flushed within 6 minutes. Generally, the first treatment of a night dispersed all gulls (min–max = 1–130 individuals) from the target roof for an extended period. Our operations were often grounded because of weather and our gull response data were limited because of few individuals present. We discuss our observations with particular attention to feasibility and possible implications such as shifting birds to other sites which, potentially, could be counterproductive for management.
Short time existence for coupling of scaled mean curvature flow and diffusion
Authors: Abels Helmut , Bürger Felicitas , Garcke Harald 
Published: January 2023

AbstractWe prove a short time existence result for a system consisting of a geometric evolution equation for a hypersurface and a parabolic equation on this evolving hypersurface. More precisely, we discuss a mean curvature flow scaled with a term that depends on a quantity defined on the surface coupled to a diffusion equation for that quantity. The proof is based on a splitting ansatz, solving both equations separately using linearization and a contraction argument. Our result is formulated for the case of immersed hypersurfaces and yields a uniform lower bound on the existence time that allows for small changes in the initial value of the height function.
Singular modules for affine Lie algebras, and applications to irregular WZNW conformal blocks
Authors: Felder Giovanni , Rembado Gabriele 
Published: January 2023

AbstractWe give a mathematical definition of irregular conformal blocks in the genus-zero WZNW model for any simple Lie algebra, using coinvariants of modules for affine Lie algebras whose parameters match up with those of moduli spaces of irregular meromorphic connections: the open de Rham spaces. The Segal–Sugawara representation of the Virasoro algebra is used to show that the spaces of irregular conformal blocks assemble into a flat vector bundle over the space of isomonodromy times à la Klarès, and we provide a universal version of the resulting flat connection generalising the irregular KZ connection of Reshetikhin and the dynamical KZ connection of Felder–Markov–Tarasov–Varchenko.
Overcoming obstacles in insect utilization
Authors: Baigts-Allende Diana K. , Stathopoulos Constantinos 
Published: January 2023

AbstractEdible insects have long been part of human diets in some countries, and they are expected to become an important alternative food source because of their nutritional value and favorable environmental impact. However, insects’ consumption safety and consumer acceptance are still significant barriers to market positioning, mainly in Western regions. Therefore, several processing technologies have been applied to develop insect-based food products and derivatives to increase consumer safety, shelf-life, and sensorial properties, including appearance. The processing pathway for insects as food might then be focused on eliminating such concerns. However, even though there is enough information related to processing techniques for edible insects, the use of the treated material has been limited as a substitute rather than a main constituted nutritional component. Moreover, there is little information about novel technologies and uses of insect derivatives compared to the minimally processed insect, as in the case of flours. This review presents the food safety (biological and chemical hazards) and cultural aspects of difficulties of eating insects and the role of processing raw material, extraction of insect derivatives (lipids and proteins), and food prototypes development on safety and consumer acceptance.
Graphical abstract
Kardar–Parisi–Zhang Equation from Long-Range Exclusion Processes
Authors: Yang Kevin 
Published: January 2023

AbstractWe prove here that the height function associated to non-simple exclusion processes with arbitrary jump-length converges to the solution of the Kardar–Parisi–Zhang SPDE under suitable scaling and renormalization. This extends the work of Dembo and Tsai (Commun Math Phys 341(1):219–261, 2016) for arbitrary jump-length and Goncalves and Jara (Stoch Process Appl 127(12):4029–4052, 2017) for the non-stationary regime. Thus we answer a "Big Picture Question" from the AIM workshop on KPZ and also expand on the almost empty set of non-integrable and non-stationary particle systems for which weak KPZ universality is proven. We use an approximate microscopic Cole-Hopf transform like in Dembo and Tsai (2016) but we develop tools to analyze local statistics of the particle system via local equilibrium and work of Goncalves and Jara (2017). Local equilibrium is done via the one-block step in Guo et al. (Commun Math Phys 118:31, 1988) for path-space/dynamic statistics.
Overexpression of the Persimmon Abscisic Acid DkUGT3 Gene Alters Plant/Fruit Development in Transgenic Tomato
Authors: Wang Juan , Xu Yandan , Yin Zhaonan , Peng Liangyu , Li Qian , Leng Ping 
Published: January 2023

AbstractPersimmon (Diospyros kaki Thunb.) contains numerous uridine diphosphate glucosyltransferases (UGT), and their roles in fruit development and quality formation have not been well studied because of limited genetic information. This study investigated a persimmon DkUGT3 which is highly expressed in young fruits and leaves during development. DkUGT3 can catalyze ABA glycosylation to form ABA-GE, thereby reducing free ABA. Tomato with overexpressed (OE) DkUGT3 significantly induces pale green color phenotypes in both transgenic young plants and fruits. DkUGT3-OE significantly weakens the tomato ABA signaling which affects the expressions of ABA-inducible transcriptional factors (TFs), such as GLK1 and GLK2 and their downstream target genes involved in chlorophyll synthesis, chloroplast development, sugar metabolism and transport, and photosynthesis, thereby impeding leaf and fruit development and quality. Conversely, DkUGT3-RNAi-treatment recovered the OE tomato fruits from yellowing phenotype to green color. This study found that chlorophyll accumulations and ABA level were increased by DkUGT3-RNAi-treatment in young persimmon leaves. These results demonstrate that DkUGT3 plays crucial roles in ABA-mediated leaf and fruit development. This study provides new evidence for the regulation of ABA in early development.
Are we still too late? Timing of orchidopexy
Authors: Schmedding Andrea , van Wasen Felix , Lippert Ralf 
Published: January 2023

AbstractAn undescended testis is the most common genitourinary disease in boys. The German guidelines, first published in 2009, proposed the timing of orchidopexy to be before 12 months of age. The aim of the study was to analyze the implementation of these guidelines 10 years after publication. The national cumulative statistics of hospital admissions, provided by the Institute for the Remuneration System in Hospitals (InEK), and the statistics concerning procedures performed in private pediatric surgical practices of the professional association of pediatric surgeons (BNKD) regarding the time of surgeries for the year 2019 were analyzed. Data from InEK included all German hospital admissions. Data from BNKD included data from 48 private pediatric surgical practices. The hospitals treated 6476 inpatients with undescended testis, and 3255 patients were operated in private practices. Regarding the age at treatment, 15% of the hospital patients and 5% of the private practice patients were younger than 1 year and fulfilled the guideline recommendations. Forty percent of the hospital patients and 29% of the private practice patients were 1 or 2 years of age. All other patients were 3 years of age or older at the time of orchidopexy. Conclusions: The rate of orchidopexy within the first 12 months of life is remarkably low even 10 years after the publication of the guidelines. Awareness of the existing guideline must be increased for both referring pediatric and general practitioners.

What is Known:• In Germany, orchidopexy is performed by pediatric surgeons and urologists either in hospital settings or in private practices.• Most international guidelines set the age for surgical treatment of undescended testis between 12 and 18 months of age. The German guidelines, published in 2009, sets the time-limit at one year of age. Until five years after publication of the German guidelines, the number of patients treated before the first year of life was low; studies show an orchidopexy ratebetween 8% and 19% during this time.

What is New:• This study the first to cover all administered hospital patients in Germany and a large group of patients treated in private practices. It contains the largest group of German patients with undescended testis.• Although almost all children participate in the routine check-up at the age of seven months, which includes investigation for undescended testis, adherence to the orchidopexy guidelines is still low. Only 15% of the hospital patients and 5% of the patients in private practice were treated before their first birthdays.
Ein Kupferbeil aus der frühen Kupferzeit vom Heuberg bei Ohlstadt, Deutschland
Authors: Pechtl Joachim , Strobl Susanne , Haubner Roland 
Published: January 2023

ZusammenfassungEin am Heuberg bei Ohlstadt gefundenes Flachbeil aus Kupfer, welches typologisch dem frühen Jungneolithikum respektive der frühen Kupferzeit und somit der Zeit um 4000 v. Chr. zuzuordnen ist, wird im Rahmen der Studie materialkundlich untersucht. Eine RFA-Analyse ergab nahezu reines Kupfer mit geringen Mengen an Fe, P, Si, Ni und Al. Die Elemente As, Sb, S und Pb, die in derartigen Kupfergegenständen oft zu finden sind, waren nicht nachweisbar. Die metallographische Untersuchung zeigt ein sehr gleichmäßiges Gefüge mit feinem Cu-Cu2O Eutektikum. Aufgrund der Menge an Eutektikum wird der O Gehalt im Metall auf etwa 0,3 Gew. % geschätzt.Die einzelnen Kupferkörner sind mit einer Größe zwischen 300–400 µm als grob zu bezeichnen. Auffallend ist, dass im Bereich der Beilschneide eine deutliche Verformung des Gefüges feststellbar ist. Diese dürfte durch gezieltes Hämmern entstanden sein. Aufgrund des Fehlens von S und As im Kupfer kann davon ausgegangen werden, dass nur oxydische Erze für die Kupfergewinnung verwendet wurden.
Evaluation of a city-wide physical activity pathway for people affected by cancer: the Active Everyday service
Authors: Humphreys Liam , Frith Gabriella , Humphreys Helen , Crank Helen , Dixey Joanne , Greenfield Diana M , Reece Lindsey J 
Published: January 2023

Abstract
Purpose
The primary goal of this article is to present an evaluation of a UK-based city-wide physical activity pathway for patients with a cancer diagnosis, the Active Everyday service. Active Everyday was a co-produced physical activity service for people affected by cancer. The service was underpinned by a behaviour change care pathway model developed by Macmillan Cancer Support charity.

Methods
This was a retrospective evaluation assessing physical activity levels and changes to outcome measures (fatigue, perceived health, and self-efficacy) over 6 months. Each participant self-reported their levels of physical activity for the previous 7 days at three-time points: baseline (T1), at 12-week exit from the scheme (T2), and at 6-month follow-up (T3).

Results
The Active Everyday service received 395 referrals, of which 252 attended a baseline assessment. Participants’ fatigue and self-efficacy improved between T1 and T2 and T1 and T3. Perceived health improved across all time points. Participant exercise levels showed significant differences between T1 and T2.

Conclusion
The service, provided over 3 years, resulted in positive health and wellbeing outcomes in people affected by cancer who engaged in the service. Future services must routinely include exercise referrals/prescriptions as a standard part of care to help engage inactive individuals. Services should focus on targeted promotion to people from ethnic minority groups, and a wide socioeconomic population.