bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of anaemia in pregnancy using ‘test and treat’ strategy: hospital based open randomized study
Authors: Ramachandran Prema , Sharma Anshu , Ravinder P , Nair Madhavan , Kalaivani K 
Published: August 2023

In India, prevalence of nutritional anaemia due to iron, folic acid and vitamin B12 deficiency is high. National anaemia control programme envisaged detection and treatment of anaemic pregnant women. Prevalence of anaemia continues to be high because this strategy was not operationalised and coverage and compliance with iron folic acid supplementation remains low. : The present study aimed at: 1. Operationalizing Hb estimation in urban maternity center, 2. assessing prevalence of iron, folic acid and vitamin B12 deficiency, 3. undertaking an open randomized study in women with Hb between 8.0 and 10.9 g/dL to assess impact of supplementation with iron and folic acid (Group 1) or iron, folic acid and vitamin B 12 (Group 2). The ‘Test and treat’ strategy was operationalized in urban maternity center. At enrolment 100% of women were anaemic, 60% had ferritin &#60;12ng/ml, 5% had folic acid &#60;3ng/ml and 1/3 had vitamin B12 &#60;200pg/ml. After eight weeks of supplementation, there was an increase in mean Hb (&#62;1.0 g/dL), mean ferritin and folic acid in both Gr 1 and 2. There was a fall in mean vitamin B12 at 8 weeks in Gr 1 women who received 5 mg folic acid. Addition of vitamin B12 to IFA does not improve mean Hb or vitamin B12.With assured regular supply and supportive supervision, iron folic acid supplementation for 8 weeks reduces prevalence of anaemia in pregnancy by 50%; with continued supplementation till 38 weeks of pregnancy, there was 70% reduction in prevalence of anaemia.
Assessment of Nigerian journalists’ preparedness for reporting election results and disputes
Authors: Abimbola Raphael Olugbenga 
Published: August 2023

Electoral process in Africa especially in Nigeria is a long route which often times leads to results being disputed in the courts and sometimes end in crisis. The media play a significant role in this process given their enormous influence on the public. This study examined Nigerian journalists’ preparedness for covering election results and disputes with a focus on the 2023 general elections. Anchored on symbolic interactionism theory, the study adopted survey to gauge the opinions of journalists from the six states of southwest Nigeria which form study population. A structured questionnaire was administered on 300 respondents of 50 per state selected through non-proportional quota sampling. Findings revealed that majority of the journalists are well conscious of their role in reporting election results and disputes and that their respective media organisations prepare them for such duties through training and supply of tools with less provision of funds to facilitate their task on the field. Most of the respondents also agreed that other bodies like the Nigerian Press Council, Nigeria Union of Journalists, Civil societies and international organisations, prepare them better for election coverage than their media organisations through training, funding, and tools. The study concludes that Nigerian journalists, being aware of their role in reporting elections, are more prepared for the task by external bodies other than employers and recommends that media organisations should deploy more resources to preparing their reporters for the job.

Keywords: Agenda-setting, Election Results, Election Disputes, Nigerian Journalists, Symbolic interactionism
Dissociation and Subsequent Stable Malrotation of Femoral Stem Within Sleeve After Sivash-Range of Motion Total Hip Arthroplasty
Authors: Pathak Neil , McDonald Erik , Radford Zachary J. , Gibson David H. 
Published: August 2023

Case:
A 78 year-old man fell 6 months after Sivash-range of motion (S-ROM) total hip arthroplasty (THA), after which he developed hip pain and external rotation deformity. Imaging showed stem malrotation in relative retroversion. Revision THA was delayed because of medical issues, occurring 1.5 years after the fall. No corrosion was observed intraoperatively at the stem-sleeve interface. His symptoms resolved after revision THA.

Conclusion:
We present a rare complication of S-ROM THA—dissociation of the femoral stem from the proximal sleeve, with subsequent re-engagement in static malrotation. No corrosion was observed, suggesting that the stem had stably reseated within the sleeve.
Femoral Magnetic Lengthening After Distal Femur Endoprosthetic Reconstruction in a Pediatric Patient
Authors: Tran Tina H. , Hanna Sarah M. , Gundle Kenneth R. , Yang Scott 
Published: August 2023

Case:
A 10-year-old boy with osteosarcoma of the left distal femur underwent resection with compressive osseointegration endoprosthetic reconstruction, gradually resulting in a 4.5-cm leg-length difference with significant predicted progression. Two years after resection, he underwent right distal femur and proximal tibia epiphysiodesis and placement of a left femoral magnetic lengthening nail. At 2 years after lengthening and skeletal maturity, the patient has symmetric limb lengths, no pain, and returned to sports.

Conclusion:
A magnetic lengthening nail with contralateral epiphysiodesis is a viable option for correcting limb-length discrepancy after distal femur endoprosthetic reconstruction in a pediatric patient.
Posterior Wall Acetabular Fracture After Low-Energy Trauma Masquerading as Infection
Authors: Compton Tyler , Credille Kevin , Loeffler Taylor , Graf Alexander , Van Valin Scott 
Published: August 2023

Case:
A 12-year-old adolescent boy presented after a low-energy fall with groin pain, inability to bear weight, painful passive range of motion, fever, elevated inflammatory markers, and upper respiratory symptoms. Initial radiographs did not demonstrate any abnormality, and magnetic resonance imaging suggested infection. Posterior wall acetabular fracture was not diagnosed until a computed tomography–guided biopsy was performed.

Conclusion:
Pediatric acetabular fractures are exceedingly rare. They can be difficult to diagnose after low-energy trauma as symptoms mimic infectious hip pathologies. Children presenting with infectious hip symptomology and a history of trauma may benefit from more extensive trauma imaging before costly and invasive infectious diagnostic procedures.
Damping Identification From Subsea Logger Axial Riser Response Data
Authors: Lim HyeongUk , McNeill Scot , Kluk Daniel , Stahl Matthew , Puskarskij Konstantin , Hansen Kristian 
Published: August 2023

Summary
For decades, it has been known that, as drilling riser deployment depths increase, the potential for excessive hookload response will also increase. Using data collected from a drilling riser deployed to a record-setting water depth, nearly 12,000 ft, this paper provides insight that significantly reduces uncertainty about the severity of this resonant response.
The typical drilling riser and blowout preventer (BOP) stack, disconnected from the wellhead, has its first axial resonant period at approximately 1 second for every 2,000 ft of deployed length, thus 5 seconds for 10,000 ft, 6 seconds for 12,000 ft, and so on. Therefore, vessel heave response can incite a significant, adverse axial resonant condition in very deep water. Damping reduces resonant response. Historically, the true amount of damping has been uncertain, and damping has been applied in the form of hydrodynamic drag. This typically produces a predicted response with total damping that is well under 1% of critical. This can lead to the prediction of a large dynamic hookload that can produce significant restrictions on riser configuration (running weight) and seastate for BOP stack deployment as well as storm hang-off of the riser and lower marine riser package (LMRP).
A recent drilling riser deployment to the record-setting water depth of 11,903 ft produced a unique opportunity to collect high-quality data that reduces damping uncertainty. This paper describes damping ratio and natural frequency identification for the first few axial riser modes for this deployment. The data were collected during deployment and retrieval using subsea vibration data loggers (SVDLs) installed on the BOP stack, drillship, and riser. These measurements reveal damping that is between 2% and 3% of critical. This result can be used to provide more accurate predictions of dynamic hookload response.
Role of Reservoir Brine and Rock in Modulating Asphaltene Stability: Insights from Experimental Analysis
Authors: Punase Abhishek Dinesh , Hascakir Berna 
Published: August 2023

Summary
The stability of asphaltenes in crude oil is influenced by various factors, including interactions with reservoir components such as brine and rock formations. While previous research has focused on pressure and temperature effects, a comprehensive understanding of the combined impact of brine and reservoir rock on asphaltene stability is lacking. This study investigates the individual and combined influences of brine and rock formations on asphaltene stability.
First, 11 crude oil samples from diverse locations were characterized using API gravity, viscosity, and saturates, aromatics, resins, and asphaltenes (SARA) fraction analysis. The elemental composition of the crude oils, including carbon, hydrogen, nitrogen, and various metals, was determined. The surface properties of asphaltenes were analyzed using scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM-EDS). The interaction between asphaltenes and deionized water was examined through zeta potential, particle size, conductivity, and pH measurements. The behavior of asphaltenes in an 8,000 ppm NaCl solution was also investigated.
The SEM analysis revealed the presence of inorganic content on the surfaces of asphaltenes, indicating interactions between asphaltenes and reservoir rock. A strong correlation between the zeta potential and sulfur content of asphaltenes was observed, highlighting the influence of sulfur compounds on surface charge and stability in heavy crudes. Additionally, the correlation between total dissolved solids (TDS) content and alkaline Earth metals and alkali metals in asphaltenes confirmed interactions between asphaltenes and reservoir brine. This interaction is likely influenced by the composition and properties of both the brine and reservoir rock. The presence of electrical charges on the asphaltene surfaces, as determined by zeta potential measurements, further supports the role of electrostatic interactions in asphaltene stability. The low precipitation tendency observed for most asphaltene samples, coupled with the abundance of negatively charged particles, underscores the importance of electrical charges in controlling stability.
This study provides novel insights into asphaltene stability, highlighting the significance of surface charge and elemental composition. The results demonstrate the substantial impact of both reservoir brine and rock formations on asphaltene stability in crude oil. Further research is needed to unravel the complex mechanisms underlying these interactions and their implications in diverse reservoir environments.
The organizational dimension in rare diseases care management: an application of RarERN Path© methodology in the rare neurological diseases Ataxia, Dystonia and Phenylketonuria
Authors: Cannizzo Sara , Quoidbach Vinciane , Benson Monika , Federico Antonio , Filla Alessandro , Gilroy Bernadette Sheehan , Giunti Paola , Graeßner Holm , Greenfield Julie , Hagedorn Tobias , Hermida Alvaro , Hunt Barry , McDonald Anita , Morgante Francesca , Oertel Wolfgang , Pastores Gregory , Pauly Martje , Reinhard Carola , Relja Maja , Treacy Eileen , Spronsen Francjan Van , Vallortigara Julie , Turchetti Giuseppe 
Published: August 2023

Abstract
Background. The organization of care has a deep impact on the variability in the quality of care provided to patients and on the equity of care access. The lack of coordination of care, the lack of communication among health care providers, healthcare professionals and patients, the duplication of many services that are provided to the patients, represent some paradigmatic examples of organizational barriers and crucial issues to manage in the achievement of delivering high quality patient-centered care and the promotion of equitable access to healthcare services everywhere in Europe independently from the place where the patients live. This work represents the first application of the RarERN Path©methodology for the re(design) of Patient Care Pathways (PCP) outside the rare and complex connective tissue and musculoskeletal diseases (rCTDs) covered by ERN ReCONNET where the methodology was developed, through a productive collaboration between the group of Health Economics of the Institute of Management of Scuola Superiore Sant’Anna and the Value of Treatment (VOT) for Rare Brain Disorders (Ataxia, Dystonia and Phenylketonuria) research project undertaken in 2019-2022 by the European Brain Council (EBC).
Results. Ataxia, Dystonia and Phenylketonuria (PKU) all share similar challenges: delayed diagnosis, barriers to access specialized care and treatment options, psychological burden, transition from pediatric care to adult care. The application of some of the phases of RarERN Path methodology enabled the translation of the good practices already in place in the centres of expertise into a common optimized PCP, one for each or the three rare neurological diseases, integrating the expertise of some reference centers of excellence members of ERN RND and MetabERN with the patients’ perspectives, and principally focusing on the organization of care for Ataxia, Dystonia and PKU.
Conclusions. The PCPs proposed for Ataxia, Dystonia and PKU are the results of a co-designed optimized process integrating a) the good practices of the centers of excellence and expertise in Ataxia, Dystonia and PKU, also belonging to two of the 24 European Reference Networks for rare diseases (ERN RND and MetabERN), with b) the perspectives of the patients’ representatives. This integrated approach allowed to re-design and to optimize the organizational dimensions of the patients care pathways.
Anticancer analysis of CD44 targeted Cyclosporine loaded thiolated chitosan nanoformulations for sustained release in triple-negative breast cancer.
Authors: Abduh Maisa Siddiq 
Published: August 2023

Abstract
Cyclosporine (CsA), a potent immunosuppressive chemotherapeutic medication, treats numerous cancers, particularly malignant carcinoma, acute leukemia, and triple-negative breast cancer (TNBC). A specified polymeric nanoformulation (N.F.) based drug delivery technique with ligand alteration at the surface was developed to improve active moiety delivery at the intended area and boost the efficacy of prolonged treatment. We produced and characterized N.F. of encapsulated Cyclosporine in thiolated chitosan (T.C.) with the outermost coating of hyaluronic acid (H.A.). Research in-silico verified that H.A. binds to the receptor CD44 at docking locations A and B in triple-negative breast cancer cells. When a pharmaceutical substance interacts with a polymeric compound, zeta examination reveals a particle size of 192nm, a PDI of 0.433, and zeta potential of 38.9 mV. FTIR and Raman's investigations also support the existence of hydrophobic groups, porous surfaces, and clumping characteristics. While XRD verified its crystallographic nature, which renders N.F. particularly helpful in localized drug delivery systems (DDS), SEM and TEM revealed circular nanoparticles with sleek exteriors. DSC demonstrated that N.F. was stable at high temperature. The NF showed 85% drug encapsulation, and a kinetics investigation of drug release revealed that the N.F. obeyed the Higuchi model for dispersion at low pH. In contrast to typical CsA's immediate release in under 12 hours, the in-vitro investigation demonstrated prolonged continuous dissolution at pH 7.4 and 6.8 for a maximum of 72 hours. When compared to raw Cyclosporine, the in-vitro tumor prevention properties of the ThC-HA encapsulated with Cyclosporine were tested using an MTT test on normal breast epithelial cells and triple-negative breast cancer cells. It showed the synthesized N.F.'s robust cytotoxic potential at reduced concentrations and its effectiveness for normal cells. These characteristics improve the long-term viability, effectiveness, and active targeting of prepared novel N.F.s as an effective pharmaceutical component and potent therapeutic moiety against cancer.
Proteins of Pycnoporus sanguineus have nematicide activity and induce resistance to Meloidogyne spp. in Micro-Tom tomato plants
Authors: BRITO OLIVIA DIULEN COSTA , Schons Bruna Caroline , Cecatto Roberto , DALEVEDOVE DIEGO BORGES , Fujimoto JULIANA Habitzreuter , Stangarlin José Renato 
Published: August 2023

Abstract
The aim of this research was to get protein-fractions from the aqueous extract of P. sanguineus through gel filtration chromatography (GFC) to induce resistance to Meloidogyne spp. in Micro-Tom tomato plants. Precipitation of protein from the aqueous extract (AE) of basidiocarps was performed based on increasing ethanol gradients 20%, 40%, 60%, 80% and 95%, which were individually centrifuged. Each ethanol-protein precipitate (EPP) was fractionated by using GFC, and isolated proteins (IP) were identified based on molecular mass. Each EPP and IP were tested in vitro for nematicide and nematostatic activity against M. incognita and M. javanica, through motility and mortality evaluation. Regarding resistance induction assays, root samples were also collected for the analysis of defense enzymes peroxidase (POX), polyphenoloxidase (POL) and phenylalanine ammonia-lyase (FAL). Six IP (named as I, II, III, IV, V and VI) were obtained through GFC, which molecular weights were 4.81, 47.98, 0.17, 25.78, 4.25 and 4 KDa, respectively. P. sanguineus basidiocarps contain proteins with no nematicide/nematostatic effects but capable of reducing M. javanica infection in Micro-Tom tomato plants, which can occur by resistance induction involving peroxidase activity.
WITHDRAWN: Fabrication of a novel hydrophilic ion-imprinted polymer based on silica-modified magnetic graphene oxide as a sensitive sorbent for the fast separation of silver ions from aqueous media
Authors: Taghizadeh Majid , Shafizadeh Fatemeh 
Published: August 2023

Abstract
This paper aimed to evaluate the co-precipitation preparation of a novel magnetic graphene oxide ion-imprinted polymer for the recognition and separation of silver ions in aqueous solutions. The synthesis of this adsorbent was established by thermal copolymerization of 4-vinyl pyridine (4-VP) as a functional monomer, salen as a ligand, silver ions as a template ion, ethylene glycol dimethacrylate (EGDMA) as the crosslinking agent, acetonitrile and chloroform as the solvents, 2,2-azobisisobutyronitrile (AIBN) as an initiator by coating on the surface of magnetic graphene oxide as a magnetic core. The prepared polymer was morphologically characterized by the use of several characterization techniques. A batch-wise adsorption investigation was carried out to determine favorable conditions for proper adsorption, likewise selectivity and reusability. The kinetics of the adsorption process was pseudo-second order and followed the Langmuir isothermal model. The maximum adsorption capacity was 77.6 mg g− 1 at a pH of 4. The involvement of other competing ions revealed that the adsorbent benefits from the selective property of the imprinted cavities.
Dynamic Evolution Mechanism of Dual-Channel Supply Chain for Green New Products Based on Equilibrium Price
Authors: Zhao Hua , Feng Yu , Li Ping , Wu Zhuoran 
Published: August 2023

Abstract
As public awareness of green environments grows and environmental protection regulations strengthen, the production and sales of environmentally friendly products have become crucial for traditional manufacturers. In this paper, we examine the pricing problem and coordination strategy between a manufacturer and a traditional retailer in a dual-channel supply chain of green products. The manufacturer sells both traditional and new green products through respective offline and online channels. Using a dynamic model to analyze the price game of the dual-channel supply chain, we investigate the effects of delay time lag, price adjustment speed, and green input level on the equilibrium price of the new green product. We obtain the Nash equilibrium point and stability region through the eigenvalue method and conduct numerical simulations. Our study shows that the trajectory of the product price evolution depends on system parameters, and that an optimal level of green input exists to maximize the manufacturer's profit. Our research emphasizes the importance of pricing strategies and coordination between manufacturers and retailers in the dual-channel supply chain of new green products. Overall, our findings provide valuable insights for traditional manufacturers seeking to leverage the growing demand for environmentally friendly products.
“Cold turkey meds again”: Access to community HIV/AIDS services during public health emergencies
Authors: Whittaker Darby , Monette Erynn , Bisung Elijah 
Published: August 2023

Abstract

Background
This paper works to explore the experiences of people living with HIV (PLWH) in relation to the closure of AIDS Service Organizations (ASOs) in Ontario, Canada during the COVID-19 pandemic and offers reflections on how to ensure a continuum of care for PLWH during public health emergencies like COVID-19.
Methods
Semi-structured in-depth interviews were conducted with PLWH (n = 8) and ASO service providers (n = 8). Participants discussed their experiences with HIV services throughout the pandemic.
Results
Of the PLWH interviewed, individuals shared experiences of worsening mental health outcomes, difficulties accessing resources, disruption in medical care, and increased feelings of isolation. ASO service providers identified changes in their functions, increased barriers in service provision, and staff fatigue as challenges to their work.
Conclusion
The results from this study demonstrate the need for reimagining HIV/AIDS and other service provision during pandemics to ensure that resources remain accessible for PLWH and other marginalized populations. Essential ASO services to maintain a continuum of care during pandemic circumstances include prioritizing mental health supports, regular access to nutritious food, clothing, and financial support, and consistent check-ins between clients and service providers.