bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oocyte dynamics for Atlantic bluefin tuna (Thunnus thynnus) in the southern Gulf of Mexico: A comparative assessment of Mediterranean spawners using two stereological methods
Authors: Cruz‐Castán Roberto , Saber Sámar , Meiners‐Mandujano César , Gómez Vives María José , Curiel‐Ramirez Sergio , Galindo‐Cortes Gabriela , Macías David 
Published: July 2023

AbstractAlthough most research focused on the northern Gulf of Mexico for western Atlantic bluefin tuna, the histological records of reproductive activity of this species in the southern Gulf of Mexico (Mexican waters) have been presented for the first time. This work is the first to study oocyte dynamics in Atlantic bluefin tuna caught in the southern Gulf of Mexico by assessing and comparing them with Mediterranean stock (BFT‐E) through stereology using two different methods. Regardless of Atlantic bluefin tuna females returning to their respective spawning grounds at different months in the southern Gulf of Mexico and the Mediterranean, both stocks arrived reproductively inactive and remained in these zones during periods of similar length; they were reproductively active until March for the southern Gulf of Mexico and May for the Mediterranean females. The comparison of the size structure between the two stocks examined using kernel density estimators demonstrated a quite remarkable difference in mean fork lengths between stocks. The ovarian oocyte density, that is, the number of oocytes per gram of ovary, for each gonad stage predicted using the Weibel and Gomez and oocyte packing density (OPD) methods did not significantly differ between stocks and showed that advanced vitellogenic oocytes from spawning‐capable females are an appropriate indicator to estimate potential fecundity, presenting values of c. 1273 and ~1355 eggs per gram for the southern Gulf of Mexico and Mediterranean females, respectively. Females caught in Mexican waters (southern Gulf of Mexico) were larger than those caught in the Mediterranean; however, it was demonstrated that the length and weight of females did not affect ovarian oocyte density production. In addition, densities estimated for each gonad stage using W&G and OPD methods did not differ between stocks and presented equal patterns in their oocyte dynamics. These findings contribute to a better understanding of the reproductive biology of Atlantic bluefin tuna, especially in the southern Gulf of Mexico, due to the lack of information regarding this zone, and may allow to support strategies for proper assessment, management, and conservation.
A mobile health application for patients eligible for statin therapy: app development and qualitative feedback on design and usability
Authors: Cao Weidan , Li Lang , Mathur Puneet , Thompson John , Milks M. Wesley 
Published: July 2023

Abstract
Background
Cardiovascular disease is the leading cause of death in the United States (US). Despite the well-recognized efficacy of statins, statin discontinuation rates remain high. Statin intolerance is a major cause of statin discontinuation. To accurately diagnose statin intolerance, healthcare professionals must distinguish between statin-associated and non-statin-associated muscle symptoms, because many muscle symptoms can be unrelated to statin therapy. Patients’ feedback on muscle-related symptoms would help providers make decisions about statin treatment. Given the potential benefits and feasibility of existing apps for cardiovascular disease (CVD) management and the unmet need for an app specifically addressing statin intolerance management, the objectives of the study were 1) to describe the developmental process of a novel app designed for patients who are eligible for statin therapy to lower the risk of CVD; 2) to explore healthcare providers’ feedback of the app; and 3) to explore patients’ app usage experience.

Methods
The app was developed by an interdisciplinary team. Healthcare provider participants and patient participants were recruited in the study. Providers were interviewed to provide their feedback about the app based on screenshots of the app. Patients were interviewed after a 30 days of app usage.

Results
The basic features of the app included symptom logging, vitals tracking, patient education, and push notifications. Overall, both parties provided positive feedback about the app. Areas to be improved mentioned by both parties included: the pain question asked in symptom tracking and the patient education section. Both parties agreed that it was essential to add the trend report of the logged symptoms.

Conclusions
The results indicated that providers were willing to use patient-reported data for disease management and perceived that the app had the potential to facilitate doctor-patient communication. Results also indicated that user engagement is the key to the success of app efficacy. To promote app engagement, app features should be tailored to individual patient’s needs and goals. In the future, after it is upgraded, we plan to test the app usability and feasibility among a more diverse sample.
Comparison between corn and potato starch-based bioplastic :
thermal variation
Authors: Soni Praveen 
Published: July 2023

Abstract
The development in the field of bioplastic has become the revolutionary step against the use of
conventional plastic. Bioplastic has been prepared from plants, bacterial and algal sources and
commonly bioplastic is made by starch sources i.e. potato, rice ,maize , jackfruit and corn.
However, the existing property of bioplastic has not been completely replenished over the use
of plastic. Both starch sources (potato and corn) were used to prepare bio-plastic under similar
conditions. Similar ingredients are to be used so that variation in the properties can be easily
identified. The potato starch based bio-plastic specimen shows comparable better ease in
molding and takes less time to thicken than the corn starch. The observation suggests that
bioplastic preparation can be optimized as per the requirements such as time , molding expenses
with temperature variation.
Gender differences in sensory sensitivity in ASD patients aged 2 to 15
Authors: Amiri Niloufar Mohtasham , Alizadeh Mehdi 
Published: July 2023

Abstract
Background
Despite the high prevalence of sensory processing difficulties in children with autism spectrum disorder (ASD), research with a focus on the sex differences in sensory processing is limited contributing to later diagnosis, referral, and interventions. This study aimed to assess the gender differences in sensory sensitivity in ASD children.
Methods
190 youth with ASD,(age range 2–15 years,131 male and 59 female) were assessed in the Iran Autism Association clinic. The proportions of sensitivity present in Tactile / Taste Smell / Movement/ Visual and Auditory items and also the TOTAL SCORE were analyzed as a binomial outcome and compared between females and males. Patients were divided into four age groups and sensitivity by age group plots also were analyzed.
Results
In taste smell sensitivity and visual auditory sensitivity higher scores (indicating higher sensitivity) were found in females compared to males. Although movement sensitivity in females at younger ages was less than in males, at older ages it has been found that females are more sensitive to movement.ASD females showed higher scores at tactile sensitivity than males at older ages, compared to younger ages between 9 to 11 years.
Conclusion
Sex differences in sensory sensitivity were observed in ASD children aged 2 to 15, with females being more sensitive to ST/VA than males. On the other hand in total score and movement sensitivity, females got more scores at older ages. These findings reinforce the need to take a developmental approach to understand sex differences which may have diagnostic, prognostic and treatment implications.
The complete mitochondrial genome assembly of Capsicum pubescens reveals key evolutionary characteristics of mitochondrial genes of two Capsicum subspecies
Authors: Li Lin , Lu Xu , Fu Huizhen , Wang Zhiwei 
Published: July 2023

Abstract
Pepper (Capsicum pubescens), one of the five domesticated pepper species, boasts unique characteristics such as numerous hairs on the epidermis of its leaves and stems, black seeds, and vibrant purple flowers. Previously, no studies have reported on the complete assembly of the mitochondrial genome (mitogenome) of C. pubescens. Understanding the mitogenome is crucial for further research on C. pubescens. In our study, we successfully assembled the first mitogenome of C. pubescens, which has been assigned the GenBank accession number OP957066. This mitogenome has a length of 454,165 bp and exhibits the typical circular structure observed in most mitogenomes. We have annotated a total of 70 genes, including 35 protein-coding genes (PCGs), 30 tRNA genes, 3 rRNA genes, and 2 pseudogenes. Compared to the other three pepper mitogenomes (KJ865409, KJ865410, and MN196478), C. pubescens OP957066 exhibits 4 unique PCGs (atp4, atp8, mttB, and rps1), while 2 PCGs (rpl10 and rps3) are absent. It's worth mentioning that each of the three pepper mitogenomes (KJ865409, KJ865410, and MN196478) experienced the loss of 4 PCGs (atp4, atp8, mttB, and rps1). To further explore the evolutionary relationships, we reconstructed a phylogenetic tree using the mitogenomes of C. pubescens and fourteen other species. The structural comparison and synteny analysis of the above four pepper mitogenomes showed that C. pubescens has a higher sequence similarity with KJ865409, and C. pubescens experienced rearrangements with the other three pepper mitogenomes. Interestingly, we observed 72 homologous sequences between the mitochondrial and chloroplast genomes, which accounted for 12.60% of the mitogenome, with a total length of 57,207 bp. These sequences encompassed 12 tRNA genes and the rRNA gene (rrn18). Remarkably, selective pressure analysis suggests that the nad5 gene underwent obvious positive selection. Furthermore, the single base mutation in three genes (nad1, nad2, and nad4) resulted in amino acid change. This study has provided a high-quality mitogenome of pepper, offering valuable molecular data for future investigations into the genetic information exchange between organelle genomes in pepper.
A theoretical study on gas-phase reactions of Acrolein with NO 3 : mechanism, kinetics and insights
Authors: Zhang Yunju , Zhao Meilian , Liu Mingxing , Zuo Qiwen , Wang Zhiguo , Song Ruojing , Sun Yuxi , Song Lini , Xiaokun Gou 
Published: July 2023

Abstract
The explicit reaction mechanism and dynamics of acrolein (CH2 = CHCHO) with NO3 were researched. NO3 might add to the carbon atom of C = C double bond of CH2 = CHCHO to generate IM1 (CH2ONO2CHCHO) and IM2 (CH2CHONO2CHO), and IM1 and IM2 could mutual transformation. Moreover, IM1 and IM2 could also generate a five-membered ring adducts (IM3), and then generate corresponding products. In addition, NO3 could abstract the H atom of acrolein, and the most pathway is abstracted the H atom of the -CHO group to generate h-P3 (CH2CHCO + HNO3). The H-abstraction reactions are more feasible than the addition reaction in energy. The subsequent reactions of IM1 (CH2ONO2CHCHO), IM2 (CH2CHONO2CHO) and h-P3 were detailed investigated. The computed total rate constant increase with the temperature raising from 200–3000 K, and the rate constant is 1.43 ×10− 15 cm3 molecule− 1 s− 1 at 298 K, which is consistent with the experimental values. The lifetime of Acrolein oxidized by NO3 radicals is estimated to be 14.20 days. Our theoretical investigations are of significant in understanding the oxidation process of unsaturated aldehyde by NO3.
Environmental Landscape Art Design Based on Visual Neural Network Model in Rural Construction
Authors: Wang Lu-Yao , He Yi-Ping 
Published: July 2023

Abstract
As the resources of social development continue to tilt to the countryside, the speed of rural construction continues to accelerate. In recent years, because of the higher quality of lifestyles, the demand of rural environment landscape art has gradually increased. In order to assist rural construction and improve the artistic quality of its environmental landscape, this paper proposes an environmental landscape art design method based on a visual neural network model. Firstly, the Swin Transformer text encoder is used to characterise the landscape art demand in rural construction. Then, the text feature vector of landscape art demand is input into the GAN model to generate the image content of rural construction. Finally, to better evaluate the landscape art level of the above methods in this paper, we propose an evaluating method for the landscape designing tasks. We conduct the experiments and achieve the FID value of 15.23, which can demonstrate that our method can effectively carry out an environmental landscape design for rural construction and simplify the process of rural construction. The landscape design evaluation method can evaluate the environmental landscape design accurately by the accuracy of over 80 %, and further improve and optimise the acceptance link of rural construction.
Integrated analysis of plasma proteome and cortex single-cell transcriptome reveals the novel biomarkers during cortical aging
Authors: Niu Rui-Ze , Feng Wan-Qing , Yu Qing-Shan , Shi Lan-Lan , Qin Qing-Min , Liu Jia 
Published: July 2023

BackgroundWith the increase of age, multiple physiological functions of people begin gradually degenerating. Regardless of natural aging or pathological aging, the decline in cognitive function is one of the most obvious features in the process of brain aging. Brain aging is a key factor for several neuropsychiatric disorders and for most neurodegenerative diseases characterized by onset typically occurring late in life and with worsening of symptoms over time. Therefore, the early prevention and intervention of aging progression are particularly important. Since there is no unified conclusion about the plasma diagnostic biomarkers of brain aging, this paper innovatively employed the combined multi-omics analysis to delineate the plasma markers of brain aging.MethodsIn order to search for specific aging markers in plasma during cerebral cortex aging, we used multi-omics analysis to screen out differential genes/proteins by integrating two prefrontal cortex (PFC) single-nucleus transcriptome sequencing (snRNA-seq) datasets and one plasma proteome sequencing datasets. Then plasma samples were collected from 20 young people and 20 elder people to verify the selected differential genes/proteins with ELISA assay.ResultsWe first integrated snRNA-seq data of the post-mortem human PFC and generated profiles of 65,064 nuclei from 14 subjects across adult (44–58 years), early-aging (69–79 years), and late-aging (85–94 years) stages. Seven major cell types were classified based on established markers, including oligodendrocyte, excitatory neurons, oligodendrocyte progenitor cells, astrocytes, microglia, inhibitory neurons, and endotheliocytes. A total of 93 cell-specific genes were identified to be significantly associated with age. Afterward, plasma proteomics data from 2,925 plasma proteins across 4,263 young adults to nonagenarians (18–95 years old) were combined with the outcomes from snRNA-seq data to obtain 12 differential genes/proteins (GPC5, CA10, DGKB, ST6GALNAC5, DSCAM, IL1RAPL2, TMEM132C, VCAN, APOE, PYH1R, CNTN2, SPOCK3). Finally, we verified the 12 differential genes by ELISA and found that the expression trends of five biomarkers (DSCAM, CNTN2, IL1RAPL2, CA10, GPC5) were correlated with brain aging.ConclusionFive differentially expressed proteins (DSCAM, CNTN2, IL1RAPL2, CA10, GPC5) can be considered as one of the screening indicators of brain aging, and provide a scientific basis for clinical diagnosis and intervention.
Health-Related Quality of Life and Adherence to Physical Activity and Screen Time Recommendations in Schoolchildren: Longitudinal Cohort Ciao Corona
Authors: Haile Sarah R. , Gunz Samuel , Peralta Gabriela P. , Ulytė Agnė , Raineri Alessia , Rueegg Sonja , Yasenok Viktoriia , Radtke Thomas , Puhan Milo A. , Kriemler Susi 
Published: July 2023

Objectives: We investigated changes in adherence to physical activity (PA) and screen time (ST) recommendations of children and adolescents throughout the pandemic, and their association with health-related quality of life (HRQOL).Methods: 1,769 primary (PS, grades 1–6) and secondary (SS, 7–9) school children from Ciao Corona, a school-based cohort study in Zurich, Switzerland, with five questionnaires 2020–2022. HRQOL was assessed using the KINDL questionnaire. PA (≥60 min/day moderate-to-vigorous PA) and ST (≤2 h/day ST) recommendations followed WHO guidelines.Results: Adherence to PA recommendations dropped in 2020 (83%–59% PS, 77%–52% SS), but returned to pre-pandemic levels by 2022 (79%, 66%). Fewer children met ST recommendations in 2020 (74% PS, 29% SS) and 2021 (82%, 37%) than pre-pandemic (95%, 68%). HRQOL decreased 3 points between 2020 and 2022, and was 9.7 points higher (95% CI 3.0–16.3) in March 2021 in children who met both versus no recommendations.Conclusion: Adherence to WHO guidelines on PA and ST during the pandemic had a consistent association with HRQOL despite longitudinal changes in behavior.
Efectos de tres tecnicas de riego sobre los rendimientos y eficiencia en el uso del agua por la vid (Vitis vinifera L.) En el valle de Guadalupe, Bajacalifornia
Authors: Valenzuela-Solano César , Díaz Gerardo Martínez , Moreno Víctor M. Rodríguez , Hernández-Martínez Rufina 
Published: July 2023

En la costa de Ensenada en Baja California, se elaboran los vinos de mayor calidad y se producen el 90% de los vinos mexicanos. Actualmente esta importante actividad vitivinícola enfrenta una seria crisis de falta de agua para el riego debido al agotamiento de los mantos acuíferos. La escasez de agua pone en riesgo la producción de la vid y el vino, y el bienestar de los habitantes de la zona. Dada la baja disponibilidad de agua, es imperativo incrementar la eficiencia de uso en el viñedo. con el fin de contribuir a la rentabilidad y sustentabilidad de la viticultura. Una opción es encontrar técnicas de riego alternativas a la que generalmente usan los viticultores. En el presente estudio se evaluaron las siguientes: 1) Riego de goteo convencional; 2) Secado Parcial de la Zona Radicular y 3) Riego Subsuperficial modificado, bajo un diseño de bloques al azar con cinco repeticiones. Las variables medidas fueron: rendimiento de frutos, peso por fruto, eficiencia en el uso del agua, longitud de brotes, y °Brix y pH en los frutos. A las variables se les corrieron análisis de varianza y la prueba DMS. Las técnicas de riego no afectaron significativamente los rendimientos de frutos. La técnica secado parcial redujo significativamente la longitud de los brotes, y los °Brix y pH en los frutos. Esta misma técnica promovió una mayor eficiencia en el uso del agua, al requerirse 199 lt para producir un kg de frutos, esto es 10% menos agua que es el convencional.
A Medicina Veterinária Forense na identificação de Puma concolor (Linnaeus, 1771) vítima de atropelamento com base em parâmetros morfométricos inerentes a espécie
Authors: Dallabrida Vanessa Eloisa , Calixto Suellen Rodrigues , Koslinski Aline , Companhonhi Lucas Ryan Silverio , Grassi Humberto Atílio , De Souza Rodrigo Antônio Martins , Peres Jayme Augusto 
Published: July 2023

Enquanto a medicina veterinária forense relaciona os conhecimentos científicos referentes à profissão, às leis e às atividades judiciais relacionadas à saúde e bem-estar animal, a tanatologia forense procura estabelecer a identificação do cadáver, o mecanismo e a causa da morte, bem como, o diagnóstico diferencial médico-legal. A onça-parda possui ampla distribuição no Brasil e ocorre em quase todos os biomas. No entanto, a supressão e fragmentação de seus habitats leva a retaliação destes animais por predação de animais domésticos, por caçadores e atropelamentos. O presente trabalho relata o caso de um animal da espécie Puma concolor, vítima de atropelamento, encaminhado ao Laboratório de Anatomia Patológica da Universidade Estadual do Centro-Oeste (UNICENTRO) para identificação e realização de exame necroscópico, visando confirmar a espécie e a causa mortis, sob a ótica da medicina veterinária legal e da tanatologia forense. A identificação do animal ocorreu baseada em padrões de coloração de pelagem, formato da cabeça, orelha, órbitas oculares, dentição e características das patas, dispostos em literatura. Identificar espécies silvestres, mesmo que em procedimentos necroscópicos, é importante para o levantamento da fauna local, permitindo catalogar as espécies de ocorrência e as problemáticas que afetam a vida selvagem. Desta forma, de acordo com o observado na literatura e comparando com os achados em necrópsia, permitiu-se classificar o animal como pertencente a espécie Puma concolor, o qual teve a sua causa mortis ocasionada por choque hipovolêmico e colapso cardiorrespiratório oriundo de processo traumático, em decorrência do atropelamento sofrido.
Ethnosurvey of Medicinal Plants Used in Treatment of Diabetes by the People of Nsukka, South Eastern-Nigeria
Authors: Odoh Uchenna Estella , Ezema Constance , Osadebe Patience Ogoamaka , Uzor Philip Felix , Akunne Theophine Chinwuba , Ezugwu Christopher Obodike , Chukwuma Michael Onyegbulam , Onyekere Peculiar Feena , Longinus Odoh , William Agubata Chuka , Chukwuemeka Ugwoke Christopher 
Published: July 2023

Introduction: Diabetes Mellitus is a widely prevailing Disease condition. Prior to the advancement of synthetic medicine, local remedies have been used in different parts of the world for the management of this disease. This study aims to identify the plants used by the people of Nsukka Local Government Area of Enugu State, Nigeria in the management of diabetes, and document all relevant information on them.
Methodology: A survey was conducted using semi-structured and personal oral interview methods. Consent was obtained from a total of 130 respondents, (women and men) who were interviewed on the plants used in the management of diabetes in the local government area. Available literature was searched for information on the identified plants.
Results: The study revealed 41 plant species belonging to 29 families are commonly used for treatment of diabetes in Nsukka LGA. Annonaceae, Liliaceae and Rubiaceae were the families most represented, with 3 species each. The leaves of the plant were mostly used (37.7%), and Decoction was the main mode of preparation (58.5%).
Conclusion: The forests and bushes of Nsukka Local Government Area, South Eastern-Nigeria is habitat to more than 40 plants belonging to 29 families that are used in ethnomedicinal practice as anti-diabetic agents. The plants have medicinal (including antidiabetic) uses in other places. Some of these plants have been scientifically evaluated for phytochemical composition and pharmacologically screened for anti-diabetic, and other activities.
Experimental determination of static characteristics of loads in nodes of a 6 kv power supply system
Authors: Bigun Alexander Ya. , Vladimirov Leonid V. 
Published: July 2023

Subject of research: static characteristics of nodes of 6 kV power supply systems with asynchronous load.
Purpose of research: experimental determination of static characteristics by active and reactive power, calculation of the reserve coefficient by static stability of a node with asynchronous load.
Object of research: power supply systems with a complex load, which includes asynchronous motors.
Main results of research: the results of an active experiment to determine the static characteristics of the load node are presented. The measurements were carried out using devices that record the quality of electricity. Voltage regulation was carried out by the RPN device, the current transformers on the input switch were selected as the connection point of the device. Static characteristics of active and reactive power were constructed using interpolation and extrapolation tools. The critical voltage of the load node is determined. The coefficient of static stability margin is determined.