bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep cross-domain transfer for emotion recognition via joint learning
Authors: Nguyen Dung , Nguyen Duc Thanh , Sridharan Sridha , Abdelrazek Mohamed , Denman Simon , Tran Son N. , Zeng Rui , Fookes Clinton 
Published: August 2023

AbstractDeep learning has been applied to achieve significant progress in emotion recognition from multimedia data. Despite such substantial progress, existing approaches are hindered by insufficient training data, leading to weak generalisation under mismatched conditions. To address these challenges, we propose a learning strategy which jointly transfers emotional knowledge learnt from rich datasets to source-poor datasets. Our method is also able to learn cross-domain features, leading to improved recognition performance. To demonstrate the robustness of the proposed learning strategy, we conducted extensive experiments on several benchmark datasets including eNTERFACE, SAVEE, EMODB, and RAVDESS. Experimental results show that the proposed method surpassed existing transfer learning schemes by a significant margin.
Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes respectively, exploit ureides differentially to mitigate the deleterious effects of cadmium toxicity
Authors: Zdunek-Zastocka Edyta , Grabowska Agnieszka , Michniewska Beata , Orzechowski Sławomir , Compart Julia , Fettke Joerg , Sagi Moshe 
Published: August 2023

Abstract
Purpose
Ureides, allantoin and allantoate, are N-rich compounds used for N transport in nodulated ureide legumes. Here, we investigated their role in response of Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes, respectively, to Cd toxicity.

Methods
First, ureide content and ureide metabolism in P. vulgaris and P. sativum grown under control conditions and treated with 50 μM CdCl2 for 48 hours was investigated. Then, the effect of exogenous allantoin and its precursor, uric acid, on Cd-related oxidative lesion was examined in both legumes.

Results
Cd increased the content of both ureides only in the leaves of P. vulgaris, which was consistent with transcript levels and activity of ureide metabolic enzymes, and was accompanied by an increase in uric acid content. In P. sativum leaves, Cd increased the activity of ureide biosynthesis enzymes and decreased the activity of ureide degradation enzymes, although the uric acid content did not change, while the allantoin and allantoate contents were significantly reduced. Exogenous uric acid and allantoin suppressed Cd-induced H2O2 and O2 accumulation and alleviated the effects of oxidative damage measured by RNA degradation, chlorophyll and malondialdehyde content in both legumes.

Conclusions
P. sativum use allantoin and uric acid as antioxidant agents to mitigate Cd-related oxidative tissue damage. In P. vulgaris, the involvement of the ureide pathway in Cd-induced N salvage and recycling is rather a priority.
Differences in need-supportive teaching toward students from different socioeconomic backgrounds and the role of teachers’ attitudes
Authors: Bloem Jonne , Flunger Barbara , Stroet Kim , Hornstra Lisette 
Published: August 2023

AbstractAccording to Self-Determination Theory, teachers can enhance their students’ motivation, engagement, and learning through need-supportive teaching, which involves providing autonomy support, structure, and involvement. However, within classes, there appears to be great variation in the degree to which teachers support students’ psychological needs. The current studies aimed to investigate to what extent this differentiation in need support was associated with students’ socioeconomic background. Additionally, we examined whether teachers differentiated their need support more strongly when they had more biased Explicitly or Implicitly measured attitudes toward students from a low socioeconomic background. We conducted two studies: Study 1 was a vignette study representing a fictional student from a high or low socioeconomic background, and Study 2 was a field study where teachers reported on the need support provided to real students from a high and low socioeconomic background from their own class. Findings of both studies indicated that teachers reported lower levels of involvement for students from a low compared to a high socioeconomic background. Moreover, in Study 2, teachers reported to provide students from a low socioeconomic background with less autonomy support and more structure compared to students from a high socioeconomic background. However, these differences in autonomy support and structure seemed to be related to other student characteristics, namely students’ gender, and teachers’ perceptions of students’ academic ability and classroom behavior. Furthermore, we revealed that teachers differentiated their need support more strongly when they had more biased attitudes toward low socioeconomic backgrounds.
JQ1 attenuates contrast-induced acute kidney injury through the upregulation of autophagy and inhibition of inflammation
Authors: Ge Linghong , Chen Juntao , Ren Xueying , Huang Chunqi , Dong Danqing , Yin Zhou 
Published: August 2023

Abstract
Purpose
Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital-acquired AKI. However, there is a paucity of efficacious interventions for the management of CI-AKI. Here, we aim to investigate the effects of JQ1 in CI-AKI and provide theoretical data and a foundation for novel ideas for the clinical treatment of CI-AKI.

Methods
In this study, we performed in vivo and in vitro experiments with mice and HK2 cells injury models respectively. The levels of serum creatinine (Cr) and blood urea nitrogen (BUN) were determined by an automatic analyzer for the measurements of renal function. The viability of HK-2 cells was analyzed using the Cell Counting Kit-8 (CCK-8) kit. Additionally, the kidney changes in the mice were detected using histopathology (H&E) and immunofluorescent staining. The mRNA and protein expressions were assessed using Quantitative real-time PCR and western blot, respectively. Autophagy and apoptosis was analyzed by Transmission electron microscopy (TEM) and TUNEL assay respectively.

Results
The results demonstrated that JQ1 exhibited potency of attenuating CI-AKI in mouse and HK2 cells. JQ1 increased the expression levels of Atg5, Atg7 and LC3B-II, and decreased the protein levels of p62 in the kidney and HK-2 cells. However, the combined use of JQ1 with chloroquine reversed the effects of JQ1. JQ1 also inhibited the inflammatory cells and downregulated the expression of some inflammatory cytokines (IL-6, IL-1β, TNF-α, and IFN-γ).

Conclusion
JQ1 protects against CI-AKI by promoting autophagy and inhibiting inflammation and JQ1 may be a promising therapeutic strategy for CI-AKI.
Non-target ROIMCR LC–MS analysis of the disruptive effects of TBT over time on the lipidomics of Daphnia magna
Authors: Jafari Jamile Mohammad , Casas Josefina , Barata Carlos , Abdollahi Hamid , Tauler Romà 
Published: August 2023

Abstract
Introduction
This study has investigated the temporal disruptive effects of tributyltin (TBT) on lipid homeostasis in Daphnia magna. To achieve this, the study used Liquid Chromatography–Mass Spectrometry (LC–MS) analysis to analyze biological samples of Daphnia magna treated with TBT over time. The resulting data sets were multivariate and three-way, and were modeled using bilinear and trilinear non-negative factor decomposition chemometric methods. These methods allowed for the identification of specific patterns in the data and provided insight into the effects of TBT on lipid homeostasis in Daphnia magna.

Objectives
Investigation of how are the changes in the lipid concentrations of Daphnia magna pools when they were exposed with TBT and over time using non-targeted LC–MS and advanced chemometric analysis.

Methods
The simultaneous analysis of LC–MS data sets of Daphnia magna samples under different experimental conditions (TBT dose and time) were analyzed using the ROIMCR method, which allows the resolution of the elution and mass spectra profiles of a large number of endogenous lipids. Changes obtained in the peak areas of the elution profiles of these lipids caused by the dose of TBT treatment and the time after its exposure are analyzed by principal component analysis, multivariate curve resolution-alternative least square, two-way ANOVA and ANOVA-simultaneous component analysis.

Results
87 lipids were identified. Some of these lipids are proposed as Daphnia magna lipidomic biomarkers of the effects produced by the two considered factors (time and dose) and by their interaction. A reproducible multiplicative effect between these two factors is confirmed and the optimal approach to model this dataset resulted to be the application of the trilinear factor decomposition model.

Conclusion
The proposed non-targeted LC–MS lipidomics approach resulted to be a powerful tool to investigate the effects of the two factors on the Daphnia magna lipidome using chemometric methods based on bilinear and trilinear factor decomposition models, according to the type of interaction between the design factors.
Undisturbed Posidonia oceanica meadows maintain the epiphytic bacterial community in different environments
Authors: Rotini Alice , Conte Chiara , Winters Gidon , Vasquez Marlen I. , Migliore Luciana 
Published: August 2023

AbstractSeagrasses harbour different and rich epiphytic bacterial communities. These microbes may establish intimate and symbiotic relationships with the seagrass plants and change according to host species, environmental conditions, and/or ecophysiological status of their seagrass host. Although Posidonia oceanica is one of the most studied seagrasses in the world, and bacteria associated with seagrasses have been studied for over a decade, P. oceanica’s microbiome remains hitherto little explored. Here, we applied 16S rRNA amplicon sequencing to explore the microbiome associated with the leaves of P. oceanica growing in two geomorphologically different meadows (e.g. depth, substrate, and turbidity) within the Limassol Bay (Cyprus). The morphometric (leaf area, meadow density) and biochemical (pigments, total phenols) descriptors highlighted the healthy conditions of both meadows. The leaf-associated bacterial communities showed similar structure and composition in the two sites; core microbiota members were dominated by bacteria belonging to the Thalassospiraceae, Microtrichaceae, Enterobacteriaceae, Saprospiraceae, and Hyphomonadaceae families. This analogy, even under different geomorphological conditions, suggest that in the absence of disturbances, P. oceanica maintains characteristic-associated bacterial communities. This study provides a baseline for the knowledge of the P. oceanica microbiome and further supports its use as a putative seagrass descriptor.
Association of growth and differentiation factor-15 with coronary artery calcium score and ankle-brachial index in a middle-aged and elderly Caucasian population sample free of manifest cardiovascular disease
Authors: Kiss Loretta Zsuzsa , Nyárády Balázs Bence , Pállinger Éva , Lux Árpád , Jermendy Ádám Levente , Csobay-Novák Csaba , Soós Pál , Szelid Zsolt , Láng Orsolya , Kőhidai László , Dinya Elek , Dósa Edit , Merkely Béla , Bagyura Zsolt 
Published: August 2023

AbstractGrowth and differentiation factor-15 (GDF-15) is a stress-associated cytokine of the transforming growth factor-β superfamily. The inflammatory and angiogenic effects of GDF-15 in atherosclerosis are controversial, and its correlation with the long asymptomatic phase of the disease is not well understood. Coronary artery calcium score (CACS) and ankle-brachial index (ABI) are sensitive markers of subclinical atherosclerosis. To date, only a few studies have examined the impact of GDF-15 on coronary artery calcification, and the association between GDF-15 and ABI has not been evaluated. Therefore, we aimed to investigate the possible relationship between serum GDF-15 concentrations and CACS and ABI in a Caucasian population sample of middle-aged (35–65 years) and elderly (> 65 years) people. In addition to recording demographic and anthropometric characteristics, atherosclerotic risk factors, and laboratory tests including serum HDL-cholesterol, LDL-cholesterol, hemoglobin A1c (HbA1c), high-sensitivity C-reactive protein, and N-terminal pro-B-type natriuretic peptide (NT-proBNP); GDF-15 level, cardiac computed tomography, and ABI measurements were also performed. A total of 269 asymptomatic individuals (men, n = 125; median age, 61.5 [IQR, 12.7] years) formed the basis of this study. Participants were divided into two groups according to their age (middle-aged, n = 175 and elderly, n = 94). Hypertension and diabetes mellitus were significantly more prevalent and CACS values and HbA1c, NT-proBNP, and GDF-15 levels were significantly higher (all p < 0.001) in the elderly group compared to the middle-aged group. Multivariate ridge regression analysis revealed a significant positive association between GDF-15 and CACS (middle-aged group: β = 0.072, p = 0.333; elderly group: β = 0.148, p = 0.003), and between GDF-15 and ABI (middle-aged group: β = 0.062, p = 0.393; elderly group: β = 0.088, p = 0.041) only in the elderly group. Our results show that GDF-15 is not only a useful biomarker of inflammation but can also predict early signs of asymptomatic atherosclerosis, especially in elderly people with chronic systemic inflammation associated with aging (inflammaging).
LCA to evaluate the environmental opportunity cost of biological performances in finfish farming
Authors: Jouannais Pierre , Gibertoni Pier Paolo , Bartoli Marco , Pizzol Massimo 
Published: August 2023

Abstract
Purpose
Mortality and suboptimal biological performance are a widespread problem in finfish farming. The associated losses constitute an environmental opportunity cost that needs to be thoroughly assessed to prioritize actions aiming at reducing the environmental impacts of finfish aquaculture. We here propose and demonstrate the use of a new parameterized and consequential LCA model of sea-trout production designed to assess the environmental opportunity costs of suboptimal biological performances, considering distinct mortalities and biological feed conversion ratios (FCRs) along the rearing process.

Methods
Primary data was collected in Danish and Italian farms to reconstitute the whole production process for sea-reared trouts. The level of detail allowed us to divide this production into seven different growth stages for which mortality and biological FCR can be assessed and modified. Excretion and valorization of fish sludge were modeled with a calibrated mass-balance model. Together with fish sludge, dead fish was modeled as valorized by anaerobic digestion. The foreground system was linked to the consequential version of ecoinvent 3.8 for which the embedded uncertainty was considered in Monte Carlo simulations. The model was used to assess the current environmental opportunity costs and evaluate the effect of losses happening at different timings along the rearing process.

Results and discussion
Results showed a low environmental opportunity cost for the current mortality rate of 5% as suppressing this mortality decreased impacts by 3.5 to 5% across impact categories. Decreasing the biological FCR decreased the environmental impacts proportionally. The timing of the losses was shown to greatly influence the environmental opportunity cost, and the same mortality rate happening in the late stages had substantially more impact than in the first stages. The valorization of the dead fish showed a negligible contribution to the reduction of impacts in the current system but showed a substantial contribution in the case of higher mortalities, such as observed for other farms and foreseen in the future.

Conclusion
The model demonstrated that assessing an opportunity cost by multiplying the lost biomass by a unique impact factor constitutes an oversimplification neglecting the losses timing and the fact that fish biomass is not a marketable product. Even though the current environmental opportunity cost for losses appeared neglectable, suboptimal biological FCR should be tackled. The model and approach can be used to project trout farming within future disease regimes and assess the trade-offs regarding fish health issues and new treatments and practices.
Getting on to the Same Page: War, Moral Fundamentalism, and Convention
Authors: Lang Gerald 
Published: August 2023

AbstractUwe Steinhoff’s The Ethics of War and the Force of Law contains an extended critique of ‘moral fundamentalism’, or the project of uncovering an individualist ‘deep morality’ of war governed by the same moral principles and rules that govern ordinary moral life, as well as a more positive account of war that depicts it as a social practice. Much of Steinhoff’s account is indebted to a series of claims involving the standing to blame, reciprocity, and the necessity and proportionality conditions on self-defence. On all these claims, Steinhoff is open to challenge. First, he is arguably over-dependent on ‘standing to blame’ considerations. Second, his commitment to reciprocity is under-explained. Third, the necessity condition does not clearly explain how conventional elements explain the formation of defensive standards. Fourth, there are problems in explaining how the distinct defensive conventions adopted by distinct communities can actually be made to get on to the same page when these communities go to war with each other.
Basic Properties of Solutions of Boundary Value Problem for the Dirac-Wave Operator
Authors: Marmolejo-Olea Emilio 
Published: August 2023

AbstractWe study local and global properties of solutions of the boundary value problem for the Dirac wave operator. This includes explicit formulas, domain of dependence, range of influence, finite propagation speed and energy estimates. We also introduce the space of Dirac wave homogeneous polynomials and the corresponding Dirac-wave conjugate functions.
Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Authors: Lyytinen Gustaf , Brynedal Amelie , Anesäter Erik , Antoniewicz Lukasz , Blomberg Anders , Wallén Håkan , Bosson Jenny A. , Hedman Linnea , Mobarrez Fariborz , Tehrani Sara , Lundbäck Magnus 
Published: August 2023

AbstractElectronic cigarette (EC) vaping is increasingly popular, despite growing evidence of adverse health effects. To further evaluate the impact of EC use on vascular health, we investigated the effects of brief EC inhalation on flow-dependent thrombus formation and microcirculation in healthy volunteers. The study was performed with a randomised double-blind crossover design. Twenty-two healthy subjects aged between 18 and 45 years with occasional tobacco use were recruited. Subjects inhaled 30 puffs of EC aerosol with and without nicotine on two occasions separated by a wash-out period of at least 1 week. Blood samples were collected at baseline and at 15 and 60 min following exposure and analysed with the Total-Thrombus-formation analysis system evaluating fibrin-rich thrombus formation and platelet thrombus formation in whole blood under flow. Microvascular function was assessed at baseline and 30 min after exposure by laser speckle contrast imaging and iontophoresis of acetylcholine and sodium nitroprusside (SNP) to evaluate the endothelium-dependent and independent pathways of vasodilation. Compared with nicotine free EC aerosol, exposure to EC aerosol with nicotine significantly increased platelet thrombus formation and fibrin-rich thrombus formation at 15 min (p = 0.017 and p = 0.037, respectively) with normalisation after 60 min. Peak SNP-mediated microvascular perfusion, i.e. endothelium-independent vasodilation, was reduced following EC vaping with nicotine compared with baseline (p = 0.006). Thirty puffs of EC aerosol with nicotine increased platelet and fibrin-dependent thrombus formation and reduced microvascular dilatation capacity. No compelling effects of EC vaping without nicotine were observed, indicating nicotine as the main effector. Trial registration: ClinicalTrials.gov Identifier: NCT04175457 URL: https://clinicaltrials.gov/ct2/show/NCT04175457
The influence of firefighters’ perceived stress on job burnout: a moderated mediation model
Authors: Lv Guoqing , Li Jie , Xu Qinghong , Zhang Hong , Wu Wenhui , Fan Xinrong , Wang Zhuo , Liu Haoyu 
Published: August 2023

AbstractTo find the repercussion of firefighters’ perceived stress on job burnout and its psychological mechanism, 488 firefighters were tested with the perceived stress scale, the self-compassion scale, the simplified coping style questionnaire, and the Maslach burnout inventory general survey. The conclusions demonstrated that perceived stress was significantly pertinent to job burnout; both self-compassion and negative coping style acted as intermediaries; the intermediary role of perceived stress in job burnout via self-compassion and negative coping style was moderated by positive coping style. The main findings suggest that firefighters’ perceived stress explicitly predicts job burnout and implicitly influences job burnout via self-compassion and negative coping style. Positive coping style moderated the link involving perceived stress and job burnout and the link encompassing perceived stress and negative coping style.
The influence of sub-technique and skiing velocity on air drag in skating style cross-country skiing
Authors: Elfmark Ola , Docter Heleen , Sandbakk Øyvind , Kocbach Jan 
Published: August 2023

AbstractIn cross-country skiing, velocities range from 2 m $${\textrm{s}}^{-1}$$

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up to more than 20 m $${\textrm{s}}^{-1}$$

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across undulating terrain, and aerodynamics can, therefore, make a large impact on performance. The aim of this study was to investigate the influence of skiing velocity on air drag for skating sub-techniques and downhill postures (tuck). Dynamic and static drag measurements for two athletes were performed in a wind tunnel in relevant velocity ranges for each sub-technique. The drag area decreased with velocity from 2 m $${\textrm{s}}^{-1}$$

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to around 10–12 m $${\textrm{s}}^{-1}$$

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, where it plateaued. No difference in air drag was found between the sub-techniques performed in upright postures (G2–G4) and thereby relatively similar frontal areas. In the G5 sub-technique performed without poling action in a lower posture, the reduced air drag was approximately 28% lower than for G2–G4 at similar velocities, and could even be reduced by an additional 21.7% by keeping the arms tucked in front of the body. In the downhill tucked postures, athletes could reduce air drag by 23% by keeping a low tuck, compared to a high tuck with straight legs. The sub-techniques were tested both dynamically and by averaging the static positions throughout the movements. The air drag was on average 6.1% lower for dynamic movements, indicating that dynamical movements like in cross-country skiing should be tested dynamically when evaluating air drag. Finally, the chosen cycle rate had minimal influence on air drag.