bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Voltage Spinel and Li2MnO3 Composite Structure Construction in LiMn0.8Ni0.2O2 for Manganese‐Based Lithium‐Ion Battery Cathode Materials
Authors: Liu Shiqi , Xiao Dongdong , Wang Boya , Wang Lihang , Wu Tianhao , Wang Yinzhong , Zhang Nian , Yu Haijun 
Published: April 2023

AbstractLayered Mn‐based oxides are promising candidates for next‐generation high‐energy‐density cathodes of rechargeable batteries owing to their prominent energy density and cost‐effectiveness. However, the obvious structural degradation such as the layered‐to‐spinel transformation, associating with deteriorated electrochemical cycle stability, hinder their extensive applications in batteries. Herein, a composite structure is designed based on a Mn‐based oxide of LiMn0.8Ni0.2O2 with a high‐voltage spinel crystal domain pre‐introduced into the parent layered structure, showing good structural stability during electrochemical process. Results show that Li2MnO3 crystal domain suffers from sluggish Li+ ions kinetics and structural transformation from layered to metastable spinel, while the pre‐introduced high‐voltage spinel crystal domain exhibits almost maintained structure, and the optimal performance near to theoretical capacity of LiMn0.8Ni0.2O2 cathode can be harvested after electrochemical activation. This design is useful for stabilizing the entire structure prior to the degradation of the parent structures, and the electrochemical contributions of layered Li2MnO3 and pre‐introduced high‐voltage spinel crystal domains are also discerned. This study provides new guidelines for designing high‐performance composite‐structure Mn‐based cathode materials by pre‐introduction of stable crystal domains.
Engineering of Self‐Aggregation‐Resistant MnO2 Heterostructure with A Built‐in Field for Enhanced High‐Mass‐Loading Energy Storage
Authors: Wang Jinxin , Guo Wei , Liu Zongxu , Zhang Qiuyu 
Published: April 2023

AbstractAlthough MnO2 has been intensively investigated for energy storage, further applications are limited by van der Waals force‐triggered self‐aggregation that always leads to poorly exposed active sites and compromised reaction dynamics, especially under high‐mass‐loading conditions. Herein, by synergistically coupling interfacial modulation with the Kirkendall effect, this work achieves in situ topological structure reorganization of MnOOH toward the high‐aspect‐ratio MnO2 heterostructure (Heter‐MnO2) with fully exposed active sites, which is ready to assemble into self‐supporting high‐mass‐loading film (30 mg cm−2) with restrained self‐aggregation. Theoretical calculation and dynamics analysis results demonstrate the generation of the built‐in field within the heterostructure, thus enhancing the electronic‐transfer and ionic‐adsorption/transport rates. As such, the 30 mg cm−2 Heter‐MnO2 electrode achieves a superior areal capacitance of 4762 mF cm−2 at 1 mA cm−2 and a sound rate performance (79% at 100 mA cm−2) comparable to those of low‐mass‐loading/thin‐film electrodes. As a proof of concept, the fabricated planar interdigital quasi‐solid‐state symmetric micro‐supercapacitor (MSC) based on the Heter‐MnO2 electrode can deliver a remarkable areal capacitance of 181 mF cm−2 and a considerable volumetric energy density of 10.3 mWh cm−3. This methodology highlights the promise of surface/interface chemistry modulation for the configuration of easy‐to‐integrate hierarchical nanostructures to better meet practical energy applications.
High‐burnout and low‐NOx combustion characteristics in a 600‐MWe W‐shaped flame furnace: Air‐regulating solution selection as varying overfire air and impact of the overfire air ratio
Authors: Qi Shengchen , Wang Xiu , Zhao Yiping , Kuang Min , Liu Sheng , Chen Yangyang 
Published: April 2023

AbstractIn order to establish an efficient air‐regulating solution as varying overfire air (OFA) and recommend an appropriate OFA ratio for a 600‐MWe W‐shaped flame furnace equipped with the proposed cascade‐arch‐firing low‐NOx and high‐burnout configuration (CLHC), four air‐regulating solutions were established by respectively adjusting the air into secondary air, tertiary air, and hopper air or proportionally varying the air into the three jets in a uniform distribution form, which were labeled in turn as SA, TA, HA, and UD, respectively. After the efficient air‐regulating solution fixed, four OFA ratios of 15%, 17.5%, 20%, and 22.5% were evaluated. Among the four air‐regulating solutions, only UD develops symmetrical combustion. An order of TA < HA < SA < UD in the final performance indexes enables UD as the efficient air‐regulating solution as varying OFA. A symmetrical flow field and combustion pattern develop at the former three OFA ratios. The excessive OFA ratio of 22.5% achieves a severely deflected flow field and asymmetric combustion. Increasing the OFA ratio generates a decrease‐to‐increase trend in burnout and a continuous decrease trend in NOx emissions. Consequently, the 20% setting is preferred as an appropriate OFA ratio, showing the best low‐NOx and high‐burnout accomplishment. The improvement in both burnout and NOx emissions as opening OFA to deepen air staging is attributed to the improved symmetrical combustion and the strengthened OFA penetration in the upper furnace.
Chemical composition, particle size, and molecular weight distributions of chemically degraded guar gum solutions
Authors: Li Yongfu , Hilliard Casie , Kuo Tzu‐Chi , Nelson Christopher , Rinken Marian , Broomall Charles , Hawkes Alice , Pearce Eric , Donate Felipe , Ouellette Sara , Kalantar Thomas H. 
Published: April 2023

AbstractChemical degradation of guar gum solutions via the addition of a strong oxidant is a common process step in hydraulic fracturing. Unfortunately, this degradation step leads to the formation of an insoluble precipitate which clogs the porous rock formation, reducing efficiency, reducing oil recovery potential, and increasing energy costs. The chemical composition, particle size, and molecular weight distributions of the oxidatively degraded guar (“broken guar”) are largely unknown, making it difficult to develop mitigation strategies. In this work, broken guar gum solutions are systematically analyzed to understand the origin of the observed residue. Our results indicate that cellulose fibers and proteins, rather than galactomannan oligomers, are the two major components (>50%) of the solid residue (the water‐insoluble fraction of broken guar). This finding suggests that removal of the cellulose fiber and proteins from the guar source material may be a potential residue mitigation strategy. Separately, we provide evidence for a potential second mitigation strategy employing chemical additives to reduce aggregation of the insoluble species, effectively reducing their potential to cause formation damage.
Sieving and hydrothermal pre‐treatments for preparing ultra‐high mechanical strength particleboard
Authors: Zhou Tong , Pang Bo , Cao Xue‐Fei , Bao Ningzhong , Zhu Chen‐Jie , Sun Zhuohua , Yang Sheng , Yuan Tong‐Qi 
Published: April 2023

AbstractThe application of non woody biomass materials in the manufacture of wood‐based panels has been confirmed as an efficient carbon sequestration approach. In this study, reed straw was recommended to produce reed‐based particleboards (RPs). Sieving and hydrothermal pre‐treatments were conducted on the inner layer reed particles to reduce the adverse influence of the waxy layer on the mechanical strength of RPs. The thickness swelling rate was merely 1.04% (2 h), and the internal bonding strength could reach up to 0.88 MPa, which met the ISO requirements for heavy‐duty load bearing in dry conditions (P‐HLB REG). More importantly, this study constructed the plate forming process that retains the natural morphological characteristics of reed to the maximum extent. Generally, the mechanical strength of RPs was markedly higher than mostly straw‐based and even wood‐based panels. The static bending strength of RPs could reach 35.6 MPa after sieving pre‐treatment. In addition, according to the LCA, the net carbon flux could reach −1227.55 kg CO2 eq. when producing 1 m3 RPs. The obtained RPs could be utilized as wood substitutes to produce furniture and building materials with promising environmental and economic benefits.
Probing Polar‐π Interactions Between Tetrazoles and Aromatic Rings**
Authors: Jian Jie , Hammink Roel , Tinnemans Paul , Bickelhaupt F. Matthias , Poater Jordi , Mecinović Jasmin 
Published: April 2023

AbstractThe heterocyclic tetrazole, a well‐established bioisosteric replacement of carboxylic acid, plays an important role in medicinal chemistry. To deepen the functional understanding of tetrazoles in chemical sciences, it is essential to investigate the noncovalent interactions between the tetrazole ring and aromatic rings. Here, we report synthetic, spectroscopic, structural and quantum chemical analyses on specially designed 2‐arylphenyl‐1H‐tetrazoles to study the underlying noncovalent interactions between the tetrazole ring and the neighboring aromatic ring possessing substituents at para/meta position. pKa values and proton affinities of 2‐arylphenyl‐1H‐tetrazoles correlate well with Hammett sigma values of para‐substituents at the flanking aromatic ring. Molecular orbital and energy decomposition analyses reveal that through‐space NH–π interactions and π–π interactions contribute to the trend of pKa values and proton affinities of 2‐arylphenyl‐1H‐tetrazoles. The electrostatic interaction between tetrazole/tetrazolide interacting with the aromatic rings appears responsible for the observed acidity trends. These results will be helpful for the rational design of tetrazole‐based drugs and materials.
Hydraulic Models, Fire Flow Tests, and Your Home Insurance
Authors:   AWWA Fire Protection Committee
Published: April 2023

Key TakeawaysThe Public Protection Classification (PPC) is used as an input in determining home insurance cost, and the available fire flow is an important input in determining the PPC.To determine a water system's available fire flow, either hydrant flow tests or hydraulic modeling can be used to calculate water main capacity.Each method has its pros and cons, and familiarity with each enables the engineer to select the best approach.
A novel Mn4+‐activated far‐red Sr2MgWO6 phosphor: synthesis, luminescence enhancement, and application prospect
Authors: Liu Xinyue , Xu Yamin , Cheng Kang , Long Juling , Huang Weichao , Deng Chaoyong 
Published: April 2023

AbstractA novel far‐red emitting phosphor Sr2MgWO6: Mn4+ was fabricated using high‐temperature solid‐state reaction. X‐ray diffraction patterns, scanning electron microscopy images, and photoluminescence excitation and photoluminescence spectra for this phosphor were analyzed in detail. The analysis revealed that its emission ranged from 600 to 800 nm and peaked at 699 nm, which was attributed to the 2Eg→4A2g transition of Mn4+ under 314 nm excitation. Moreover, we introduced rare‐earth Yb3+ ions into the Sr2MgWO6:Mn4+ to improve its far‐red emitting intensity. The photoluminescence (PL) intensity of the Yb3+ co‐doped phosphor was three times higher than that of the single‐doped phosphor. Therefore charge compensation is an efficient approach to improving PL intensity. The phosphor emitted a far‐red light that resembled the pigments essential for plant growth in terms of the absorption spectrum. Therefore, the obtained phosphor, Sr2MgWO6:0.006Mn4+,0.2Yb3+, had the potential to be a new type of far‐red luminescent powder for indoor plant growth LEDs.
YBac: A novel and simple baculovirus system for heterologous protein production in Spodoptera frugiperda 9 (Sf9) cells
Authors: Yu Yue , Yang Cancan , Zhang Tong , Xu Zhenhe , Zhang Yuanxing , Liu Qin 
Published: April 2023

AbstractThe baculovirus expression vector system (BEVS) has been widely used for heterologous protein expression due to its powerful functionality and easy access to commercial expression vectors. Currently, most laboratories prefer two strategies for protein production using BEVS. One is recombinant bacmid based on transposition in Escherichia coli (e.g., Bac‐to‐Bac), and another is homologous recombination in insect cells (e.g., flashBac). In this manuscript, a rapid and simple YBac system was established. This novel system uses an Ac99KO bacmid as a virus vector and co‐transfected into Spodoptera frugiperda 9 (Sf9) cells with a donor plasmid capable of recombination into Ac42 loci that carry the genes of interest (GOIs) along with the complete Ac99 fragment. Based on the intracellular homologous recombination system, the production of foreign proteins was achieved by the complementation of the Ac99 gene together with the insertion of GOIs. In this study, the human thyroid peroxidase (hTPO) and porcine epidemic diarrhea virus‐like particles (PEDV VLPs) were successfully expressed using the YBac system. The entire process was shortened to 10 days, and the components involved in the system could be easily prepared in the laboratory, suggesting that the YBac system may have great potential in the production of heterologous proteins.
Gambling on an empty stomach: Hunger modulates preferences for learned but not described risks
Authors: van Swieten Maaike M. H. , Bogacz Rafal , Manohar Sanjay G. 
Published: April 2023

AbstractIntroductionWe assess risks differently when they are explicitly described, compared to when we learn directly from experience, suggesting dissociable decision‐making systems. Our needs, such as hunger, could globally affect our risk preferences, but do they affect described and learned risks equally? On one hand, decision‐making from descriptions is often considered flexible and context sensitive, and might therefore be modulated by metabolic needs. On the other hand, preferences learned through reinforcement might be more strongly coupled to biological drives.MethodThirty‐two healthy participants (females: 20, mean age: 25.6 ± 6.5 years) with a normal weight (Body Mass Index: 22.9 ± 3.2 kg/m2) were tested in a within‐subjects counterbalanced, randomized crossover design for the effects of hunger on two separate risk‐taking tasks. We asked participants to choose between two options with different risks to obtain monetary outcomes. In one task, the outcome probabilities were described numerically, whereas in a second task, they were learned.ResultIn agreement with previous studies, we found that rewarding contexts induced risk‐aversion when risks were explicitly described (F1,31 = 55.01, p < .0001, ηp2 = .64), but risk‐seeking when they were learned through experience (F1,31 = 10.28, p < .003, ηp2 = .25). Crucially, hunger attenuated these contextual biases, but only for learned risks (F1,31 = 8.38, p < .007, ηp2 = .21).ConclusionThe results suggest that our metabolic state determines risk‐taking biases when we lack explicit descriptions.
3D printing‐based full‐scale human brain for diverse applications
Authors: Hua Weijian , Zhang Cheng , Raymond Lily , Mitchell Kellen , Wen Lai , Yang Ying , Zhao Danyang , Liu Shu , Jin Yifei 
Published: April 2023

AbstractSurgery is the most frequent treatment for patients with brain tumors. The construction of full‐scale human brain models, which is still challenging to realize via current manufacturing techniques, can effectively train surgeons before brain tumor surgeries. This paper aims to develop a set of three‐dimensional (3D) printing approaches to fabricate customized full‐scale human brain models for surgery training as well as specialized brain patches for wound healing after surgery. First, a brain patch designed to fit a wound's shape and size can be easily printed in and collected from a stimuli‐responsive yield‐stress support bath. Then, an inverse 3D printing strategy, called “peeling‐boiled‐eggs,” is proposed to fabricate full‐scale human brain models. In this strategy, the contour layer of a brain model is printed using a sacrificial ink to envelop the target brain core within a photocurable yield‐stress support bath. After crosslinking the contour layer, the as‐printed model can be harvested from the bath to photo crosslink the brain core, which can be eventually released by liquefying the contour layer. Both the brain patch and full‐scale human brain model are successfully printed to mimic the scenario of wound healing after removing a brain tumor, validating the effectiveness of the proposed 3D printing approaches.
On the need for structurally competent counselling and psychotherapy: Neoliberal ideology, disability and the psy disciplines
Authors: Hunt Joanne 
Published: April 2023

AbstractThis article highlights and problematises the psy disciplines' articulations with neoliberalism, with a particular focus upon disability and upon counselling and psychotherapy. Recent years have witnessed burgeoning scholarly interest in the potential complicities of the psy professions in a neoliberal agenda of individualisation, pathologisation and responsibilisation of human suffering. Such complicities are, in state therapy settings, driven by a growing need for these professions to offer cost‐effective, evidence‐based interventions to secure funding in an increasingly competitive market. Whilst the entwining of neoliberal ideology with therapy practices may be innocuous for some, it is contended that disabled people may be at particular risk of harm. A case is then made for training and practice to foreground structural competency, an awareness of how therapy encounters and client concerns are shaped by socio‐structural factors, including, but not limited to, politics and political ideology. This would require not only an appreciation of the sociopolitical context in which therapy unfolds and its indubitable shaping of subjectivities, but also greater recognition of disability as a source of social inequity and oppression, as opposed to an individual phenomenon. Moreover, structural competency would require theoretical and demographic diversity in training and practice, which, in turn, would necessitate identifying and addressing barriers to inclusion for disabled people. Points raised are deemed of particular importance given the emergence of long COVID.
Proanthocyanidins in Pruning Wood Extracts of Four European Plum (Prunus domestica L.) Cultivars and Their hLDHA Inhibitory Activity
Authors: Ortega‐Vidal Juan , Ruiz‐Martos Lucía , Salido Sofía , Altarejos Joaquín 
Published: April 2023

AbstractEuropean plum tree (Prunus domestica L.) is cultivated in many countries for its delicious and nutritive fruit and, accordingly, certain amounts of wood (from pruning works) are generated every year. The main objective of this work was to value this agricultural woody residue, for which the chemical composition of pruning wood extracts from four European plum cultivars was investigated, and the human lactate dehydrogenase A (hLDHA) inhibitory activity of plum wood extracts and pure proanthocyanidins present in those extracts was measured. For the chemical characterization, total phenolic content and DPPH radical‐scavenging assays and HPLC‐DAD/ESI‐MS analyses were performed, the procyanidin (−)‐ent‐epicatechin‐(2α→O→7,4α→8)‐catechin (4), the phenolic glucoside (−)‐annphenone (3) and the flavan‐3‐ol catechin (1) being the major components of the wood extracts. Some quantitative and qualitative differences were found among plum cultivars, and the content of proanthocyanidins ranged from 1.51 (cv. ‘Claudia de Tolosa’) to 8.51 (cv. ‘De la Rosa’) mg g−1 of dry wood. For the hLDHA inhibitory activity, six wood extracts and six proanthocyanidins were evaluated by a UV spectrophotometric assay, compound 4 showing the highest inhibitory activity (IC50 3.2 μM) of this enzyme involved on the excessive production of oxalate in the liver of patients affected by the rare disease Primary Hyperoxaluria.
Novel (E)‐3‐(3‐Oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Bioevaluation
Authors: Minh Sang Doan , Ho Na Ik , Tien Anh Duong , Thi Mai Dung Do , Thi Thu Hang Nguyen , Phuong‐Anh Nguyen T. , Hai Pham‐The , Thi Kim Oanh Dao , Thanh Tung Truong , Jung Lee Soo , Hee Kwon Joo , Soon Kang Jong , Han Sang‐Bae , Thi Thanh Hai Dinh , Nam Nguyen‐Hai 
Published: April 2023

AbstractHerein, we report the design, synthesis and evaluation of novel (E)‐3‐(3‐oxo‐4‐substituted‐3,4‐dihydro‐2H‐benzo[b][1,4]oxazin‐6‐yl)‐N‐hydroxypropenamides (4 a–i, 7 a–g) targeting histone deacetylases. Three human cancer cell lines were used to test the cytotoxicity of the synthesized compounds (SW620, colon; PC‐3, prostate; NCI−H23, lung cancer); inhibitory activity towards HDAC; anticancer activity; as well as their impact on the cell cycle and apoptosis. As a result, compounds 4 a–i bearing the alkyl substituents seemed to be less potent than the benzyl‐containing compounds 7 a–g in all biological assays. Compounds 7 e–f were found to be the most active HDAC inhibitors with IC50 of 1.498±0.020 μM and 1.794±0.159 μM, respectively. In terms of cytotoxicity and anticancer assay, 7 e and 7 f also showed good activity with IC50 values in the micromolar range. In addition, the cell cycle and apoptosis of SW620 were affected by compound 7 f in almost a similar manner to that of reference compound SAHA. Docking assays were carried out for analysis the binding mode and selectivity of this compound toward 8 HDAC isoforms. Overall, our data confirmed that the inhibition of HDAC plays a pivotal role in their anticancer activity.
Evaluation of in vitro coculture of keratinocytes derived from foreskin and adipose‐derived mesenchymal stem cells (AMSCs) on a multilayer oxygen‐releasing electrospun scaffold based on PU/PCL.Sodium percarbonate (SPC)‐gelatine/PU
Authors: Azari Arezo , Rahimi Azam , Rajabibazl Masoumeh , Abbaszadeh Hojjat Allah , Hosseinzadeh Simzar , Rahimpour Azam 
Published: April 2023

AbstractDespite significant advancements in tissue engineering and regenerative medicine during the last two decades, the fabrication of proper scaffolds with appropriate cells can still be considered a critical achievement in this field. Hypoxia is a major stumbling block to chronic wound healing, which restrains tissue engineering plans because a lack of oxygen may cause cell death. This study evaluated the cocultured human keratinocytes and human adipose‐derived mesenchymal stem cells (AMSCs) on a multilayer oxygen‐releasing electrospun scaffold based on PU/PCL.Sodium percarbonate (SPC)‐gelatin/PU. The scaffold was characterized using Fourier transform infrared (FTIR) and scanning electron microscopy (SEM) methods. Flow cytometry confirmed mesenchymal stem cells, and then the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5 diphenyltetrazolium bromide (MTT) assay and DAPI staining were used to assess the in vitro biocompatibility of the scaffold. The experimental results showed that the multilayer electrospun scaffold containing 2.5% SPC could efficiently produce oxygen. Furthermore, according to cell viability results, this structure makes a suitable substrate for the coculture of keratinocytes and AMSCs. Gene expression analysis of various markers such as Involucrin, Cytokeratin 10, and Cytokeratin 14 after 14 days confirmed that keratinocytes and AMSCs coculture on PU/PCL.SPC‐gelatin/PU electrospun scaffold promotes dermal differentiation and epithelial proliferation compared to keratinocytes single‐cell culture. Therefore, our study supports using oxygen‐releasing scaffolds as a potential strategy to hasten skin tissue regeneration. Based on the results, this structure is suggested as a promising candidate for cell‐based skin tissue engineering. Given that the developed oxygen‐generating polymeric electrospun scaffolds could be used as part of a future strategy for skin tissue engineering, the PU/PCL.SPC‐gelatin/PU hybrid electrospun multilayer scaffold in combination with keratinocyte/AMSC coculture is proposed as an effective substrate for skin tissue engineering and regenerative medicine platforms.