bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinicopathological profile of triple negative breast cancer in a tertiary health care centre of India
Authors: Ahmed Saqib , Patel Gulshan , Hasan Ruhi , Hasan Mahboob 
Published: August 2023

Breast carcinoma is one of the most common malignancies affecting women in developing countries. It is divided into several subtypes, including triple negatives. TNBCs are found to have an aggressive behaviour and have a metastasic potential leading to an overall poorer prognosis.The aim was to study the clinicopathological profile of TNBC pateints including parameters like age, site, tumour size, histopathological type, histologic grade, lymphovascular invasion and nodal invasion and TNM Staging was done to study the overall prognosis.A four year retrospective study was conducted on ninety seven cases of breast carcinoma which were further classified based on immunohistochemical staining into four subtypes. The clinicopathological details and the histomorphological features of these patents were studied.Of the 208 cases, 97 cases were diagnosed as TNBC. The average age at presentation was 45 years. Most of the cases showed Nottingham Modification of Scarff Bloom-Richardson (NMBR) grade 3 (66%) and stage II (50.7%). Lymph node metastasis and Lymphovascular invasion was seen in 62% and 24.7% of cases. Infiltrating ductal carcinoma (not otherwise specified) type (94.8%) was the most common histological type. TNBC have an aggressive behaviour compared to other subtypes with higher SBR grade. Lymphovascular invasion and nodal metastasis.
Association of E-cadherin with epidermal growth factor receptor in squamous cell carcinoma of oral cavity
Authors: Usman Syeda Iqra , Maheshwari Veena , Afroz Nishat , Ahmed Murad 
Published: August 2023

Oral cancer is the sixth most common cancer worldwide. Despite new modalities of treatment there has been no significant improvement in mortality and morbidity. E-cadherin responsible for cell-cell adhesion in epithelial tissues. It plays role in establishment and maintenance of polarity and structural integrity. Low expression helps in process of carcinogenesis. Epidermal growth factor receptor (EGFR) overexpression is found in majority of oral squamous cell carcinoma and association have been made between increased expression levels and an aggressive phenotype.To study the association of E-cadherin with epidermal growth factor receptor in different grades of oral squamous cell carcinoma.After taking informed consent from patients 75 cases of OSCC were included in the study and subjected to immunohistochemistry of E-cadherin and EGFR.It was concluded from the study that with decrease in differentiation of OSCC expression of E- cadherin decrease while expression of EGFR increases. On correlating both were found to be inversely proportional to each other.During EMT there is loss of cell adhesion molecules. In our study with decrease differentiation there is loss of E-cadherin. E-Cadherin expression was inversely correlated to EGFR expression.
Evaluation and Comparison of Fracture Toughness of Glass Fibre Reinforce Composites
Authors: Rangaswamy Nikhil , S Shivakumar , Avadhani Shriranganath P. , G A Manjunath 
Published: August 2023

The study of the behaviour of a broken structure or component under service conditions is known as fracture mechanics. Impurities, uneven curing, holes and notches are all sources of fractures. Cracks are common local discontinuities in materials caused by a variety of factors. Such discontinuities cause the structure's rigidity and consequently load bearing capability to deteriorate. It is known that for the crack to propagate, the stress in the locale of the crack tip should reach the critical value. Once stress level is critical, the crack propagates and leads to failure of the structure. A segment of the crack is divided into three modes namely Mode I (Opening mode), Mode II (sliding mode), Mode III (tearing mode). The current study presents a computational and experimental study on fractography and notch sensitivity evaluation in glass-fiber-reinforced-laminate under quasi-static load. For both numerical and experimental damage assessments, three volume fractions of glass and resin plies (50/50, 60/40, and 70/30) have been used. The fracture toughness investigation was carried out in accordance with ASTM standards, utilising a universal testing equipment. The numerical study is conducted out using the J-integral approach. The fracture toughness increases with resin content and is determined by the ductility of the plastic zone surrounding the crack tip. Within an acceptable range, the numerical findings are equivalent to the experimental values. When compared to the other modes, Mode 1 is the fatal. The mode I fracture toughness of several materials is evaluated experimentally and compared in this study.
Grain Growth Inhibition by Second Phase Particles : A Two-Dimensional Monte Carlo Computational Study
Authors: Rajendra P. , Phaneesh K. R. , Ramesha C M , Nagaral Madev , Auradi V 
Published: August 2023

A comprehensive 2-D simulation was performed on a square lattice under the influence of a second phase particle to validate the Zener limit. The effect of matrix sizes from 100 to 10,000 was examined on R(lim), R(max), Scaling constant(k), and impurities lying on the grain boundaries(ϕ). In addition, the optimum matrix size N=2000 under various second phase particles and Q states were investigated. The particle-pinned regimes developed a unique relationship between the Zener limit and the fraction of second phase particles resting on the grain boundary, i.e., R(limit)=1/eΦ It was observed that the particle fraction is proportional to the determined limiting grain size. The homogeneity and distribution of grains were observed to obey the lognormal behavior.
Measurement of Methytetrahydrofolate Level among Sudanese Women with Hypertensive Disorders of Pregnancy, Khartoum State 2023
Authors: Mohamed said Nedaa Ahmed , Alrahman Nedaa Abd , Babiker Sara Elsadig , Alabid Tyseer , Merghani Maye  M. , Babiker Nihad alsadig 
Published: August 2023

Background: Hypertensive disorders are a common complication of pregnancy that put women and their fetuses at disproportionate risk for further complications, as well as a life-long sequela. This study aimed to measure the Methytetrahydrofolate Level (folate) among Sudanese women with hypertensive disorders of pregnancy
Material and method: This was a case-control hospital-based study conducted at the laboratory of the Omdurman maternity hospital – in Khartoum, Sudan during the period of January 2023 to March 2023. It included All patients attending Omdurman maternity hospital that diagnosed with hypertensive disorders of pregnancy, and apparently healthy women were included as a control group. ELIZA (mindary 8000) was used for folate level measurement.
Results: The mean of folate levels in the cases was (12.9± 3.7), and in the control group was (33.9±2.5), when compared the folate mean between the case and control group there was a highly significant decrease with (p. v= 0.001). While the folate level had insignificant differences with the history of hypertension and types of hypertensive pregnancy (p. v > 0.05). Also has appositive correlation with the age (p. v<0.05).
Conclusion: In the Sudanese women with hypertensive pregnancy the folate level was significantly decreased when compared between the case and control group, and had insignificant differences with the history of hypertension, and types of hypertensive pregnancy and had a positive correlation with the age.
DE BAPTISTA A BAXIXA: percurso dos músicos Francisco Xavier e Joaquim Félix Xavier
Authors: Nejmeddine Mafalda S. 
Published: August 2023

Francisco Xavier Baptista é um dos compositores mais marcantes do repertório português para tecla da segunda metade do século XVIII. A sua coleção de doze sonatas figura entre as raras obras para instrumentos de tecla publicadas em Portugal essa poca. Além destas, existem duas sonatas manuscritas da sua autoria e outras duas indicando a autoria de Francisco Xavier Bachixa, num manuscrito preservado na Bibliothèque nationale de France. A partir de pesquisas biográficas e do estudo de documentação da época, este vídeo-artigo esclarece acerca do sobrenome Baxixa (ou Bachixa) e da identidade deste músico e compositor português, bem como do seu filho, Joaquim Félix Xavier.
Adsorption of Ammonia in Wastewater Using Hyacinth (Eichornia Crassipes) Powder with The Assistance of Bio Balls
Authors: Nurdin M. Ilham , Sukasri Arifah , Damayanti Jeanne Dewi 
Published: August 2023

<p><span><strong>Abstract.</strong> </span>Water pollution can be caused by the discharge of domestic wastewater containing contaminants. Ammonia is a water pollutant that has a bad impact because it can cause an unpleasant pungent odor and can inhibit or stop the growth of aquatic organisms because it interferes with oxygen binding, changes pH and affects enzymatic reactions and membrane stability in aquatic organisms. This research treats domestic wastewater contaminated with ammonia by means of adsorption using water hyacinth powder. In order to reduce ammonia contaminants in domestic wastewater. This study used a quantitative method which included the acclimatization stage, preliminary test, water hyacinth powder production, adsorption process, ammonia content analysis. The results showed that the use of water hyacinth powder in the most efficient adsorption process was 8 grams of water hyacinth powder and 60 bioballs in 10 liters of wastewater with a decrease in ammonia content of 93.47% for 24 hours. With the bioremediation process ratio, the ammonia content in wastewater can be reduced from 4.810 ppm to 0.314 ppm.</p><p> </p><p><strong>Keywords:</strong></p><p>Adsorption, Domestic Wastewater, Ammonia, Water Hyacinth Powder</p><p><strong><br /></strong></p>
The development of rubi web (rumah biologi web) in biodiversity concept
Authors: Istiana Yunvida , Mahrawi Mahrawi , Wahyuni Indria , Ratnasari Dwi 
Published: August 2023

This study aims to develop a web-based learning media, namely RUBI WEB (Rumah Biologi Web) in the concept of biodiversity. The research method used in this research is a modified development research method from Borg & Gall (2003) whose stages consist of information gathering, planning, product development, and initial field trials. Aspects of the assessment of the material assessed include aspects of material and aspects of language, then aspects of media assessment that are assessed include aspects of software engineering, aspects of instructional design, and aspects of visual communication. The results of the material feasibility test by material experts obtained a percentage value of 80% and media feasibility tests by media experts obtained a percentage value of 83.4%. The results of the user response test by students obtained a percentage value of 86. Therefore, it can be interpreted that the RUBI WEB website learning media in the concept of biodiversity is included in the grade A+ category with a range of percentile ratings between 96-100%, best imaginable adjectives category, acceptable level of acceptance, and NPS (Net Promotore Score) in class promoter, i.e. users are satisfied and loyal to RUBI WEB media, so that they can make users want to recommend this media to others
Analysis of yam starch and its application in synthesis of NiO nanoparticles using simple green method
Authors: Egu Samuel Attah , Maji D. C. , Idih O. S. , Omale A. 
Published: August 2023

Abstract
Herein, green synthesis of starch-reduced nickel oxide nanoparticles (SNiONPs) is reported. The synthesis involved the use of nickel chloride hexahydrate as a nickel precursor, starch as a reducing and capping agent and water as a solvent. By differing the reaction time, the evolution of growth of the SNiONPs was investigated. The starch and the nanoparticles were characterized using UV–Vis absorption spectroscopy, FTIR, XRD, SEM, XRF, and EDS, and the starch was studied for proximate composition. The absorption maxima of the as-synthesized materials at different reaction times showed characteristic Ni LSPR peaks. The capping of the nanoparticles was verified using FTIR, XRF and EDS analysis, and the particle size was determined using the Scherrer equation. SEM images of the starch showed oval- to egg-shaped particles, while SEM images of the nanoparticles showed dispersed oval-shaped material. The sensitivity of the SNiONPs indicated possible sensitivity in a linear response over a concentration range of 1–6 M H2O2.
Artificial Intelligence-enabled Chest X-ray DetectsOsteoporosis with Bone Mineral Density and identifies the mortality events
Authors: Tsai Dung-Jang , Lin Chin , Lin Chin-Sheng , Lee Chia-Cheng , Wang Chih-Hung , Fang Wen-Hui 
Published: August 2023

Abstract
SUMMARY
A deep learning model was developed to identify osteoporosis from chest X-ray features with high accuracy in internal and external validation. It has significant prognostic implications, identifying individuals at higher risk of all-cause mortality. This AI-enabled chest X-ray strategy may function as an early detection screening tool for osteoporosis.
OBJECTIVE
The aim of this study was to develop a deep learning model (DLM) to identify osteoporosis via chest X-ray features and investigate the performance and clinical implications.
METHOD
This study collected 48,353 CXRs with the corresponding T score according to DXA from the academic medical center. Among these, 35,633 CXRs were used to identify CXR-OP. Another 12,720 CXRs were used to validate the performance, which was evaluated by the area under the receiver operating characteristic curve (AUC). Furthermore, CXR-OP was tested to assess the long-term risks of mortality, which were evaluated by Kaplan‒Meier survival analysis and the Cox proportional hazards model.
RESULTS
The DLM utilizing CXR achieved AUCs of 0.930 and 0.892 during internal and external validation, respectively. The group that underwent DXA with CXR-OP had a higher risk of all-cause mortality (hazard ratio [HR] 2.59, 95% CI: 1.83–3.67), and those classified as CXR-OP in the group without DXA also had higher all-cause mortality (HR: 1.67, 95% CI: 1.61–1.72) in the internal validation set. The external validation set produced similar results.
CONCLUSION
Our DLM uses chest X-rays for early detection of osteoporosis, aiding physicians to identify those at risk. It has significant prognostic implications, improving life quality and reducing mortality. AI-enabled CXR strategy may serve as a screening tool.
Hermite Broad-Learning Recurrent Neural Control with Adaptive Learning Rate for Nonlinear Systems
Authors: Hsu Chun-Fei , Chen Bo-Rui 
Published: August 2023

Abstract
Although conventional control systems are simple and widely used, they may not be effective for complex and uncertain systems. This study proposes a Hermite broad-learning recurrent neural network (HBRNN) to address such challenges. The HBRNN has a wide network structure and incorporates an internal feedback loop that enables fast learning and dynamic mapping. Furthermore, a Hermite broad-learning recurrent neural control (HBRNC) with the HBRNN as the main controller is proposed. All the network parameters of the HBRNN are updated online according to parameter learning laws through the gradient descent approach. To prevent network parameter overtraining of the HBRNN, an adaptive learning rate (ALR) is established using a discrete-type Lyapunov function to determine the least upper bound for the learning rate. The ALR can dynamically adjust the learning rates within specified ranges during the training process, thus achieving an appropriate balance between convergence speed and system stability. Finally, the HBRNC system with ALR is applied to a chaotic circuit and a reaction wheel pendulum, and its effectiveness is validated through simulation and experimentation.
Breast cancer patient’s postoperative outcomes in nipple-sparing mastectomy and reconstruction with subpectoral implant placement: a single center experience
Authors: De Luca Alessandro , Amabile Maria Ida , Frusone Federico , Tripodi Domenico , Costanzo Maria Ludovica , Torre Giuseppe La , Marcasciano Marco , Torto Federico Lo , Vergine Massimo , Monti Massimo , Ribuffo Diego 
Published: August 2023

Abstract
Background: The continuous increase in the rate of nipple sparing mastectomy (NSM), the development of several reconstructive techniques and the following introduction of acellular derma matrix (ADM) has revolutionized implant-based breast reconstruction. This study aimed to investigate postoperative complications, health-related QoL and patient’s satisfaction in patients undergoing NSM and breast reconstruction with or without ADM
Methods: Enrolled patients were divided into three groups: immediate breast reconstruction (IBR) with definitive breast implant and ADM (Group A), IBR only with definitive breast implant (Group B), and two-stage breast reconstruction (Group C). The postoperative complications and BREAST-Q outcomes were compared.
Results: A total of 105 BC patients were enrolled and a total of 139 post-mastectomy breast reconstructions were performed. Seroma was the most prevalent complication observed: 8% in Group A, 3% in Group B and 6% in Group C. Postoperative infection occurred in two patients of Group A (5,5%), one patient of Group B (3%) and one of Group C (3%). Group A patients reported larger drain volume (1125 ± 243.5 cc), longer drain period (13.2 ± 2.8 days), and the lowest incidence of capsular contracture (5.6%). The BREAST-Q patient-reported outcome measures document that all patients aged ≥50 years presented a higher score in “Satisfaction with breast” (beta:5.198; p<0.001) and “satisfaction with outcome” domains (beta:5.421; p<0.05). Performing a bilateral breast reconstruction was associated to higher scores in “Physical Wellbeing Chest domain” (beta:3.278; p<0.05). In addition patients in Group A and Group B reported higher score in “Satisfaction with the breast” domain (p<0.001) but only in Group B we reported a higher score in “Satisfaction with outcome” (p<0.001).
Conclusion: Subpectoral IBR results in manageable complications and greater personal satisfaction. The ADM could improve breast reconstruction reducing the rate of capsular contracture. The pre pectoral placement of ADM could minimize complications and optimize aesthetic results.
Graph neural network recommendation algorithm based on improved dual tower model
Authors: He Qiang , Li Xinkai , Cai Biao 
Published: August 2023

Abstract
The information explosion is strongly impacting recommendation systems. The dual tower neural network model can quickly filter and score tens of millions of items in the recall phase and assemble them into a ranking recommendation. This model has attracted considerable interest from researchers and industry. However, the user and item towers operate independently in the dual tower model, so it cannot interact with information features, and its recommendation accuracy is less-than-optimal. The application of graph neural networks to recommendation systems has developed rapidly, enabling item recommendation through a high-order learning mechanism based on feature interaction between user information and item information. This paper proposes an interactive higher-order dual tower recommendation algorithm, the Interactive Higher-order Dual Tower (IHDT) model. Our model is based on an interactive learning mechanism, which combines the user's feature information into the item encoder and the item’s feature information into the user encoder simultaneously. The resulting higher-order interaction connectivity of graph neural networks is used to obtain a better representation of users and items. Finally, the model algorithm is compared with a benchmark algorithm on four public evaluation indicators on a public dataset. The experimental results show that the model performance is superior to other algorithms. The dataset file of this paper used is available at https://pan.baidu.com/s/1AEh-XNP_nJhxqrKuK0CgeA, with password: a2b4
Multi-criteria decision-making tool for investigating the feasibility of the green roof systems in Egypt.
Authors: Desouki Mahmoud , Madkour Mai , Abdeen Ahmed , Elboshy Bahaa 
Published: August 2023

Abstract
Urbanization in Egyptian cities detracts from green spaces, which reduces the per capita ratio to lower the appropriate rates, which increases the different negative environmental effects such as heat island, air pollution, and energy consumption. In addition, different social and human comfort issues have been affected. In this context, building rooftops is a potential solution that could reduce the effect of green space area reduction and have multiple evidence-based benefits. The green roof has different environmental, economic, and social benefits. Consequently, numerous governmental and private initiatives have recently appeared to spread the rooftop greening concept in Egypt. These initiatives have adopted several planting systems, such as soil-based, Deep-Water Culture, and Nutrient Film Technique systems. This paper aims to study the commonly used systems and compare them in terms of environmental and economic factors. The paper introduces a tool that could help to choose the most suitable system according to their needs and tendencies. Different methodologies have been conducted to estimate the value of factors for different systems, including literature review, expert opinion collection, market survey, and energy simulation. Also, the Analytical Hierarchy Processes methodology has been proposed to weigh the different factors in reaching a final user decision. A python code has been conducted to establish the tool and published online to be available for different decision makers and researchers.
Propolis Fluoride Inhibits Streptococcus mutans and Veillonella parvula Dual- species Biofilm Growth and alters Gene Expression
Authors: Theodorea Citra Fragrantia , Hendrawan Devin , Diven Saint , Utami Nastiti Rilo , Soekanto Sri Angky , Soedarsono Nurtami , Darwita Risqa Rina , Djais Ariadna Adisattya 
Published: August 2023

Abstract
Background
Propolis fluoride 10% (PPF) was developed to arrest and prevent caries, with inhibitory effects on a single species of bacteria. However, no study has been conducted on the effectiveness of PPF in inhibiting multispecies biofilms, particularly early colonizers. This study aimed to investigate the effects of PPF on Streptococcus mutans and Veillonella parvula (Sm-Vp) dual-species biofilm growth and gene expression.
Methods
Biofilms were prepared using the 96-well method with 1, 3, and 6 h incubation, and 30% silver diamine fluoride was used as the positive control. Crystal violet assay and total plate counting (TPC) were performed to analyze inhibitory effects. An inverted microscope was used to analyze the formed structure. RNA was extracted from the samples for cDNA synthesis and standardized using a Qubit fluorometer for reverse-transcription quantitative-polymerase chain reaction. The target genes used in this study were NRAMP and SloR, and 16 srRNA was used as an internal control. Consequently, alterations of gene expression were quantified using Livak’s method (2^-∆∆Ct). Statistical analyses were performed using the Statistical Package for the Social Sciences software. Statistical significance was set at P < 0.05.
Results
Inverted microscopic observation showed lower aggregate formation in the treated and positive control groups, whereas large aggregates were observed in the negative control groups. The TPC and crystal violet results showed a significant difference between the control and treatment groups in the monospecies group (P < 0.05), and the lower mean was statistically significant (P < 0.05). The NRAMP and SloR/Dlg gene expressions were downregulated in PPF-treated samples.
Conclusion
The PPF-treated Sm-Vp biofilms showed lower biofilm formation and altered virulence and symbiotic-related gene expression. Therefore, PPF effectively inhibits Sm-Vp biofilm growth and prevents caries.