bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protocol for a pilot randomized controlled trial of a telehealth-delivered counseling intervention to reduce suicidality and improve HIV care engagement in Tanzania
Authors: Knettel Brandon A. , Knippler Elizabeth T. , Amiri Ismail , Joel Louise , Madundo Kim , Msoka Elizabeth F. , Boshe Judith , Tarimo Clotilda S. , Katiti Victor , Rwakilomba Jackline , Turner Elizabeth L. , Minja Linda , Staton Catherine A. , Vissoci Joao Ricardo N. , Mmbaga Blandina T. , Relf Michael V. , Goldston David B. 
Published: July 2023

ObjectiveSuicidal ideation is strikingly common among people living with HIV (PLWH) worldwide, leading to higher burden of disease, poor HIV care engagement, and loss of life. In low- and middle-income countries such as Tanzania, mental health resources are scarce, requiring innovative strategies for treatment. We describe the protocol for a clinical trial of a three-session telehealth counseling intervention to reduce suicidality and improve HIV care engagement in Tanzania.MethodsIn a pilot randomized controlled trial, we will assess the feasibility, acceptability, and potential efficacy of a new telehealth intervention, termed “IDEAS for Hope”. A total of 60 PLWH will be enrolled from two HIV clinics in the Kilimanjaro region and connected to telehealth counsellors based at a large regional hospital. Participants will be ≥18 years old and speak either Kiswahili or English. Patient screening will occur during routine HIV clinical care to identify PLWH experiencing suicidal ideation. Baseline surveys will be administered upon enrollment and participants will be randomized 1:1 to receive either IDEAS for Hope or the comparison condition, a brief safety planning session. All participants will receive an additional referral for psychiatric treatment. Follow-up assessment will occur at three months. IDEAS for Hope is informed by a Motivational Interviewing-enhanced safety planning intervention (MI-SafeCope) and our formative work in Tanzania. The model consists of Four Pillars: living healthy with HIV, managing HIV stigma, seeking social support, and meeting basic needs. Together, these mechanisms serve as a foundation for developing a sense of safety and hope for the future. Outcome measures will include intervention feasibility, acceptability, participant suicidality, and HIV care engagement.SignificanceInnovative, telehealth-based counseling represents a promising treatment for suicidality among PLWH in low-resource settings. Results from this pilot trial will inform intervention refinement and parameter estimates for a future clinical trial powered to evaluate effectiveness.
Effects of an academic detailing service on benzodiazepine prescribing patterns in primary care
Authors: Lacroix Meagan , Abdelmalek Fred , Everett Karl , Salach Lena , Bevan Lindsay , Burton Victoria , Ivers Noah M. , Tadrous Mina 
Published: July 2023

Background
Benzodiazepines are commonly used to treat anxiety and/or insomnia but are associated with substantial safety risks. Changes to prescribing patterns in primary care may be facilitated through tailored quality improvement strategies. Academic detailing (AD) may be an effective method of promoting safe benzodiazepine prescribing. The objective of this study was to evaluate the effectiveness of AD on benzodiazepine prescribing among family physicians.

Methods and findings
We used an interrupted time series matched cohort design using population-based administrative claims databases. Participants were family physicians practicing in Ontario, Canada. The intervention was a voluntary AD service which involves brief service-oriented educational outreach visits by a trained pharmacist. The focus was on key messages for safer benzodiazepine prescribing in primary care with an emphasis on judicious prescribing to older adults aged 65 and older. Physicians in the intervention group were those who received at least one AD visit on benzodiazepine use between June 2019 and February 2020. Physicians in the control group were included if they did not receive an AD visit during the study period. Intervention physicians were matched to control physicians 1:4, on a variety of characteristics. Physicians were excluded if they had inactive billing or billing of less than 100 unique patient visits in the calendar year prior to the index date. The primary outcome was mean total benzodiazepine prescriptions at the level of the physician. Secondary outcomes were rate (per 100) of patients with long-term prescriptions, high-risk prescriptions, newly started prescriptions, and benzodiazepine-related patient harms. Data were analyzed using a repeated measures pre-post comparison with an intention-to-treat. Analyses were then stratified to focus on effects within higher-prescribing physicians.
There were 1337 physicians were included in the study; 237 who received AD and 1064 who did not. There was no significant change in benzodiazepine prescribing when considering all physicians in the intervention and matched control groups. Although not significant, a greater reduction in total benzodiazepine prescriptions was observed amongst the highest-volume prescribing physicians who received the intervention (% change in slope = -0.53, 95%CI = -2.34 to 1.30, p > .05).
The main limitation of our study was the voluntary nature of the AD intervention, which may have introduced a self-selection bias of physicians most open to changing their prescribing.

Conclusion
This study suggests that future AD interventions should focus on physicians with the greatest room for improvement to their prescribing.
Social support for postpartum women and associated factors including online support to reduce stress and depression amidst COVID-19: Results of an online survey in Thailand
Authors: Kim Soo Jung , Aye Yin Min , Panyarachun Danipa , Hong Seo Ah , Chang Yan-Shing 
Published: July 2023

BackgroundSocial support for postpartum women helps mothers to recover from childbirth and fosters healthy infant development. However, the impacts of reduced interpersonal interactions inflicted by the COVID-19 outbreak on available social support for postpartum women have received little attention. Therefore, this study aimed to examine the levels of social support provided to postpartum women and associated factors in Thailand during the COVID-19 pandemic.MethodsA cross-sectional study was conducted from July to October 2021 using an anonymous online questionnaire. The responses of 840 eligible women up to six months postpartum in Thailand were obtained. The maternity social support scale was used to measure social support. Multivariate logistic regression was used to analyse the factors associated with social support among postpartum women.ResultsAbout 57% of women reported to receive high support. Women in the high social support group were more likely to be married (aOR:2.70; 95% CI:1.57–4.66), have a university education or above (1.88; 1.35–2.64), have an intended pregnancy (2.06; 1.34–3.16), good health (2.01; 1.44–2.81), good sleep quality (1.62; 1.14–2.31), receive counsel from peers or family (1.56; 1.13–2.16), and use internet or social media to reduce stress and depression (1.51; 1.08–2.11). Meanwhile, women in the high social support group were significantly less likely to feed complementary foods to infants within 24 hours of completing the survey (0.28; 0.15–0.52).ConclusionsThe results of this study indicated that more than half of the women reported high support and illustrated the important role played by family, peers, and professionals as well as online and remote channels in providing postpartum informational and emotional support during the pandemic. Online platforms and remote support may be considered to provide social support to postpartum women during a pandemic such as COVID-19.
Utilization of diabetes self-management program among breast, prostate, and colorectal cancer survivors: Using 2006–2019 Texas Medicare data
Authors: Lee Wei-Chen , Digbeu Biai Dominique Elmir , Serag Hani , Sallam Hanaa , Kuo Yong-Fang 
Published: July 2023

Background
Cancer treatment is associated with inferior health outcomes such as diabetes. Medicare provides Diabetes Self-Management Training (DSMT) program to beneficiaries to achieve normal metabolic control and reduce the risk of micro and macro-vascular complications. This study aimed to examine the trend of DSMT utilization among cancer survivors and assess individual characteristics associated with it.

Methods
The data for this study was from Texas Cancer Registry-Medicare linkage data of patients with prostate, breast, or colorectal cancer diagnosed in 1999–2017. Outcome variables include the number of first-time DSMT users, the number of total users, and the average number of DSMT utilization in minutes. We performed logistic regression and gamma regression to obtain a multivariable-adjusted odds ratio for the association between DSMT utilization and individual characteristics.

Results
The number of first-time users has slowly increased over the years (from 99 to 769 per 1,000) but suddenly dropped after 2016. The number of all users (first-time and follow-up users) has increased (from 123 to 1,201 per 1,000) and plateaued after 2016. Determinants including Hispanic ethnicity (O.R. = 1.10) and Medicare-Medicaid dual eligibility (O.R. = 1.25) are positively associated with both the initiation and retention of the DSMT. A barrier to both initiation and retention of DSMT is living in a metropolitan area (O.R. = 0.90).

Conclusions
Multi-level strategies to enhance accessibility and availability of DSMT programs for Medicare beneficiaries are highly recommended. Examining the determinants of initiation and retention of DSMT over 14 years provides insights on strategies to meet the needs of cancer survivors and reduce the burden of diabetes on them.
Admissions to psychiatric inpatient services and use of coercive measures in 2020 in a Swiss psychiatric department: An interrupted time-series analysis
Authors: Wullschleger Alexandre , Gonçalves Leonel , Royston Maya , Sentissi Othman , Ambrosetti Julia , Kaiser Stefan , Baggio Stéphanie 
Published: July 2023

BackgroundThe CoVID pandemic and the associated lockdown had a significant impact on mental health services. Inpatient services faced the challenge of offering acute psychiatric while implementing strict infection control measures. There is, however, a lack of studies investigating the use of coercive measures during the pandemic and their relation to hospitalizations and symptom severity.AimsTo investigate the effects of the CoVID outbreak on psychiatric admissions, use of seclusion and symptom severity.MethodUsing routine data from 2019 and 2020 gathered in the Department of Psychiatry at the Geneva University Hospitals, we performed an interrupted time series analysis. This included the number of psychiatric hospitalizations, the proportion of people who experienced seclusion and the average severity of symptoms as measured by the Health of Nations Outcome Scale (HoNOS). Dependent variables were regressed on the time variable using regression model with bootstrapped standard errors.ResultsHospitalizations decreased over time (b= -0.57, 95% CI: -0.67; -0.48,p< .001). A structural break in the data (supremum Wald test:p< .001) was observed in the 12thweek of 2020. There was an inverse relationship between the number of admissions and the proportions of people subject to seclusion (b= 0.21, 95% CI: -0.32; -0.09,p< .001). There was a statistically marginally significant inverse relationship between HoNOS scores at admission and the number of psychiatric hospitalizations (b= -1.28, 95% CI: -2.59, 0.02,p= .054).ConclusionOur results show that the CoVID pandemic in 2020 was associated with a significant decrease in the number of hospital admissions. This decrease was correlated with a greater use of seclusion. The higher burden of symptoms and the difficult implementation of infection control measures might explain this higher use of coercion.
Learning Management with STEM Education Approach on Learning Achievement and Science Creative Thinking of Ninth Grade Students.
Authors:   Master of Education Program in Science Teaching Faculty of Education Burapha University, Tannawannapong Nattapong , Chaiprasert Pattaraporn ,   Faculty of Education Department of Learning Management Faculty of Education Burapha University, Singlop Somsiri ,   Faculty of Education Department of Learning Management Faculty of Education Burapha University, Wattanachod Kongsak ,   Assistant Professor Demonstration School "Piboonbamphen" Burapha University
Published: July 2023

The purposes of this research were to compare learning achievement and science creative thinking before and after learning, and to compare learning achievement after learning with criterion of 70 percent using STEM education approach. The participants were 28 ninth grade students from Piboonbumpen Demonstration School, Burapha University, who studied in the first semester of academic year 2018. They were selected by cluster random sampling. The research instruments were 1) lesson plans 2) learning achievement test and 3) science creative thinking test. The collected data were analyzed by arithmetic mean, percentage, standard deviation, and t-test.	The research findings were as follows 1) The post-test scores of science learning achievement of the ninth grade students after learning with STEM education were higher than those before learning at the .05 significant level. 2) The post-test scores of science learning achievement of the ninth grade students after learning with STEM education were higher than 70 % set criterion at the .05 significant level. 3) The science creative thinking of the ninth grade students after learning with STEM education were higher than those before learning at the .05 significant level.
Krajobraz wielu zmysłów na przykładzie parków kieszonkowych w Krakowie
Authors: Sołtysik Anna 
Published: July 2023

Artykuł ma na celu ukazanie parków kieszonkowych, utworzonych do tej pory w Krakowie, pod kątem aspektów związanych z ich odbiorem zmysłowym. Oprócz projektu zagospodarowania poszczególnych parków, ich wyposażenia w małą architekturę, nawierzchnie i roślinność, zostanie przeanalizowany ich potencjalny odbiór zmysłowy. Bardziej szczegółowej analizie zostanie poddany krajobraz dźwiękowy wybranych przykładów. Temat ten wiąże się z aspektami społecznymi w odbiorze krajobrazu. Służy także ukazaniu, jak poprzez umożliwienie percepcji wielozmysłowej możemy poprawić jakość przestrzeni miejskiej.
Educational intervention promotes injury prevention adherence in club collegiate men’s lacrosse athletes
Authors: Gawrys Steven P. , Wong Westin J. , Parker Lawsen M. , Bradshaw Justin T. , Starr Evan G. , Wilde Ben 
Published: July 2023

Abstract

Context
Club sports are intercollegiate athletics that are student-led and not university-funded, many of which are without professional credentialing. Collegiate club athletes have an increased rate of injury compared to their NCAA counterparts. Education and implementation of stretching and strength training have demonstrated decreased rates of noncontact injuries.

Objectives
Educational intervention was given to club collegiate athletes to determine its effect on injury rates, perceived pain, and compliance toward injury-prevention practices.

Methods
Intramural collegiate athletes were educated on injury prevention that focused on targeted stretching. Surveys designed to assess the impact of the education were distributed to three men’s club lacrosse teams in Utah at the beginning and end of the season. The questions measured pain and time missed due to noncontact injury.

Results
Two-tailed unpaired t tests demonstrated p values <0.05 for: overall decreased levels of pain (p<0.0001); increased range of motion (ROM, p<0.0001); increased frequency of stretching the muscle groups psoas (p<0.0001), calves (p=0.0081), and piriformis (p<0.0001); decreased pain levels for the hamstring (p=0.0274); and increased frequency of stretching after practice (p<0.0001).

Conclusions
The increased frequency of stretching suggests increased compliance toward injury prevention practices. Decreased self-reported levels of overall pain, and decreased pain in the hamstring, show that the subjects surveyed in the sample reported less pain and increased time stretching at the end of the season compared with the beginning of the season. Educational intervention offers an affordable measure to provide club collegiate athletes with resources to reduce injury rates through athlete compliance to targeted stretches.
Pre-treatment predictors of cardiac dose exposure in left-sided breast cancer radiotherapy patients after breast conserving surgery
Authors: Xu Lixia , Wang Hui , Wang Jiahao , Ren Yao , Zhang Lidan , Deng Wenfan , Li Xiadong 
Published: July 2023

Abstract

Objectives
This study aimed to identify high-risk factors for high cardiac radiation exposure, based on anatomical measurements taken from planning CT images of patients with left-sided breast cancer who underwent breast-conserving surgery and received radiotherapy.

Methods
We retrospectively analyzed 45 patients with left-sided breast cancer who underwent whole-breast radiotherapy, either under free breathing (27/45) or deep inspiratory breath-holding (DIBH) (18/45), after breast-conserving surgery. Six anatomical parameters were measured from planning CT images, including treatment planning target volume (PTV), cardiopulmonary volume ratio (CVR), maximum cardiac margin distance, the relative distance between inferior boundaries of heart and PTV (DBIB(H2P)), axial cardiac contact distance, and para-sagittal cardiac contact distance (CCDps). Multiple linear regression analysis was performed using SPSS software to explore the correlation between the six parameters, body mass index (BMI), and the mean heart dose (MHD). Receiver operating characteristic (ROC) analysis was performed to evaluate the predictive power of the selected predictor of cardiac dose exposure.

Results
Significant correlations were observed between the MHD of patients and the CVR, DBIB(H2P), and CCDps parameters. Among them, the CVR was the most important predictor of cardiac dose exposure, with an area under the curve of 0.915 and a cut-off value of 0.17.

Conclusions
The study results indicated that CVR, DBIB(H2P), and CCDps are the primary parameters associated with the risk of cardiac dose exposure, with CVR being the most significant predictor. Further prospective studies are required to determine whether these parameters can be used to identify patients who would benefit from the DIBH technique.
Awareness of Digital Preservation Among Pakistani Librarians
Authors: Ahmad Rafiq , Rafiq Muhammad 
Published: July 2023

AbstractFor implementation of effective and efficient digital preservation programs, librarians and other professionals in the memory institutions need to have sufficient levels of awareness of digital preservation key concepts, strategies, tools, and standards/best practices. This survey aimed to investigate the awareness of librarians in Pakistani universities about these components. The population of the study included the librarians working in the central libraries of public sector universities and degree awarding institutions (DAIs) of Pakistan established before 2010. A questionnaire was developed after reviewing the relevant literature and was thereafter pilot tested in selected libraries. After successful completion of this phase, data was collected from the target population. A total of 178 responses were received from 63 out of 70 universities and DAIs. Overall, respondents showed a good level of awareness of different components of digital preservation.
Interferon inhibits a model RNA virus via a limited set of inducible effector genes
Authors: McDougal Matthew B , De Maria Anthony M , Ohlson Maikke B , Kumar Ashwani , Xing Chao , Schoggins John W 
Published: July 2023

AbstractInterferons control viral infection by inducing the expression of antiviral effector proteins encoded by interferon‐stimulated genes (ISGs). The field has mostly focused on identifying individual antiviral ISG effectors and defining their mechanisms of action. However, fundamental gaps in knowledge about the interferon response remain. For example, it is not known how many ISGs are required to protect cells from a particular virus, though it is theorized that numerous ISGs act in concert to achieve viral inhibition. Here, we used CRISPR‐based loss‐of‐function screens to identify a markedly limited set of ISGs that confer interferon‐mediated suppression of a model alphavirus, Venezuelan equine encephalitis virus (VEEV). We show via combinatorial gene targeting that three antiviral effectors—ZAP, IFIT3, and IFIT1—together constitute the majority of interferon‐mediated restriction of VEEV, while accounting for < 0.5% of the interferon‐induced transcriptome. Together, our data suggest a refined model of the antiviral interferon response in which a small subset of “dominant” ISGs may confer the bulk of the inhibition of a given virus.
Evaluasi Penerapan Community Based Tourism (CBT)
Authors: Diana Diana , Setiawan Avi Budi 
Published: July 2023

Tourism is one of the growing sectors in Indonesia. One of the cities in Central Java that has both natural and artificial tourism potential is Pekalongan City. Nature tourism in Pekalongan City is still lacking in community involvement. The purpose of this study was to analyze the extent to which the existence and implementation as well as the obstacles in the implementation of Community Based Tourism (CBT) in these tours. Methods of data collection using interviews, observation, and documentation. The data analysis technique in this study used a narrative descriptive technique. The results showed that the community has been involved in tourism management but it is still not in accordance with the expected target. A good Community Based Tourism is the Pasir Kencana beach which is seen from the activity of a good tourism awareness group (Pokdarwis). Constraints in community-based tourism management in tourism are natural factors as well as factors from human resources.

Pariwisata merupakan salah satu sektor yang sedang berkembang di Indonesia. Salah satu Kota di Jawa Tengah yang memiliki potensi wisata baik alam dan buatan adalah Kota Pekalongan. Wisata alam di Kota Pekalongan masih kurang dalam keterlibatan masyarakatnya. Tujuan dari penelitian ini adalah untuk menganalisis sejauh mana eksistensi dan implementasi serta kendala dalam penerapan Community Based Tourism (CBT) di wisata tersebut. Metode pengumpulan data menggunakan wawancara, observasi, dan dokumentasi. Teknik analisis data pada penelitian ini menggunakan teknik deskriptif naratif. Hasil penelitian menunjukkan bahwa masyarakat sudah ikut terlibat dalam pengelolaan pariwisata namun masih belum sesuai dengan target yang diharapkan. Community Based Tourism yang baik adalah pantai pasir kencana dimana dilihat dari keaktifan kelompok sadar wisata (Pokdarwis) yang baik. Kendala dalam pengelolaan pariwisata berbasis masyarakat di wisata tersebut adalah faktor alam dan juga faktor dari sumber daya manusianya.