bluuebunny/crossref_metadata_2025_split huggingface dataset:
Die DGD als Wegbereiterin informationswissenschaftlicher Dokumentation in Deutschland
Authors: Ockenfeld Marlies 
Published: August 2023

Zusammenfassung
Vorstand und Sekretariat der Deutschen Gesellschaft für Dokumentation (DGD) haben von Anfang an Verantwortung für die Dokumentation und Informationsversorgung im Bereich von Dokumentation und Information übernommen. Die inhaltliche Erschließung als Grundlage eines zentralen Informationsdienstes für den gesamten Bereich des Informationswesens erfolgte in den ersten Dekaden bis 1976 mit der Dezimalklassifikation. Später wurden eine Fachordnung und ein Thesaurus erarbeitet. Referate, Bibliographien und Titellisten waren früh feste Bestandteile der Nachrichten für Dokumentation. Aus der ursprünglichen „Informationsstelle und Bibliothek der Deutschen Gesellschaft für Dokumentation (IBD)“ wurde 1971 schließlich das „Dokumentationszentrums für Informationswissenschaft der DGD (ZDOK)“ mit einem Dutzend hauptamtlich Beschäftigten. Sein Angebot umfasste Recherchen und Profildienste, Projekt-, Experten- und Institutionendokumentation sowie eine regelmäßige Veranstaltungsübersicht. Es nahm an internationalen Dokumentationsvorhaben sowie am überregionalen Leihverkehr teil, war nationale Sammelstelle für Thesauri und baute ab 1976 die Datenbank INFODATA auf. 1978 übergab die DGD ZDOK an die GID. ZDOK wurde zum Informationszentrum für Informationswissenschaft und -praxis (IZ), das zuletzt an der FH Potsdam angesiedelt war.
Preparation and application of epoxy cyclohexane/chitosan/methyl methacrylate composite material
Authors: Li Xuxing , Wang Xuemei , Gao Jun , Qi Yingping , Li Hua 
Published: August 2023

Abstract
As a cultural carrier of historical inheritance, paper has high cultural, historical and scientific research value. But with the passage of time and the change of the environment, many paper are aging and damaged. In order to protect the paper, epoxy cyclohexane/chitosan/methyl methacrylate composite material for paper protection was synthesized by radical grafting polymerization with potassium persulfate (KPS) as initiator and disodium hydrogen phosphate (DSP) as buffer reagent. Through single factor experiment, the synthetic condition was obtained as follows: 3 g of monomer dosage, 7.5 mL of initiator, 80 °C of reaction temperature, 3 h of reaction time. The aging test showed that the coating material could obviously improve the mechanical properties and anti-aging properties of paper. The reversibility experiment shows that the composite material has certain reversibility. The acid and alkali salt resistance experiment shows that the coating material could effectively resist external acid and alkali corrosion and protect paper. This study provides some theoretical guidance for the protection of paper cultural relics.
Performance of polycarboxylate superplasticisers in seawater-blended cement: Effect from chemical structure and nano modification
Authors: Ren Jun , Yan Shuo , Fang Yunhui , Tian Zhenhe , Li Hao , Guo Jinyi , Xing Feng , Fan Yiding , Wang Xianfeng , Ren Zengle 
Published: August 2023

Abstract
The performance of polycarboxylate superplasticisers (PCE) in cement blended with seawater (SW) depends on its molecular structure since large ions in SW significantly influenced its mechanism. The aim of this study was to investigate the effect of the molecular structure of PCE on the fresh properties of SW-blended cement pastes. A series of six PCEs with different charge densities, side chain lengths, and anchor groups were modified by introducing nanosilica and their physicochemical properties were characterised, and the performance was evaluated by determined by minislump, rheological behaviour and setting time. Finally, the potential mechanism was proposed via measurement of adsorption amount and layer thickness, and water film thickness (WFT). The results showed that the PCE with longer side chains and higher AA:HEPG ratio provided a significant improvement in the workability of cement pastes mixed with SW. According to the flow curves from the rheology experiments, analysis of the rheological behaviour of polycarboxylate superplasticisers in SW-blended cements paste by three rheological models. By adsorption measurement and WFT testing, high higher AA:HPEG ratio exhibits high sorption and WFT indicating less inhibition by ions in SW.
Aufweichen, abbremsen, abschirmen – Wirtschaftsmetaphern zwischen politischer Abgrenzung und diskursiven Allgemeinplätzen
Authors: Barkhausen David , Bloching Sven , Engeler Hannah Luisa 
Published: August 2023

Abstract
This study examines the use of metaphors in the German debate on European monetary and fiscal policy. Though the debates in this policy area garnered considerable interest among linguists, so far there is a gap concerning interdisciplinary comparative studies that examine metaphorical expressions in regard to their divergent political use. This study addresses said gap by posing two explorative research questions: Which metaphors shape the German political debate on European monetary and fiscal policy? And is there a relationship between the use of metaphors and the political perspective of the people using them?
To examine these questions, we developed an innovative methodological triangulation that combines qualitative, hermeneutic metaphorical analyses with quantitative, data-driven approaches of corpus linguistics. By analyzing the communication of eleven political actors during three debates on Eurozone policy, we identify the most salient metaphors and compare their political usage.
Our results show four types of metaphorical expressions which can be distinguished by their relative openness regarding political perspective and their respective referent. Thereby, this study firstly provides an important guide to understanding the debate at hand; secondly, sharpens the theoretical underpinnings of the comprehension of political metaphors as a whole; and thirdly, is a valuable contribution to the methodical study of metaphorical expressions in the field of applied linguistics.
The versatility of 1,4,8,11-tetraazacyclotetradecane (cyclam) in the formation of compounds of Co2+, Ni2+, Cu2+, and Zn2+ with metal ions in and out of the cyclic ligand ring
Authors: Noor Mah , Chah Hamza , Tresp David , Bernal Ivan , Lalancette Roger A. 
Published: August 2023

Abstract
Herein we report the results of preparing metal compounds (where the metal ions are Co2+, Ni2+, Cu2+, Zn2+) with the cyclic ligand 1,4,8,11-tetraazacyclotetradecane [cyclam] under a variety of conditions of metal-ligand ratios and solvent media. In all cases, we used metal Cl2·nH2O salts (except for anhydrous CoCl2), as specified. Outcome: we isolated species with a four-coordinate metal in the N4 cavity of the ligand alone, and also with either one or two additional axial ligands. Those axial ligands can be (a) a single chloride, leading to penta-coordinated moncationic products; (b) two chlorides, leading to octahedral-neutral compounds; (c) two waters, giving rise to hexa-coordinated [(cyclam)metal(H2O)2]2+ species. Finally, in the case of HCl added to the reaction medium, the cyclam can be di-protonated and appears as [(cyclam)H2]2+ in the crystals. With such a variety of products, it is not surprising that since the metal coordination numbers vary, the cyclam ligand stereochemistries are thereby affected. Interestingly, the [(cyclam)metal] species are invariably hydrogen-bonded to one another in infinite strings of two kinds: (1) those for which the crystal’s Z′ = 1 have single strings; (2) when Z′ = 2, there is a pair of homogeneous strings attached to one another by a variety of hydrogen-bonding linkages. Finally, we observed an interesting pair of hydroxonium cations: the first is hydoxonium cations in a pleated 2-D sheet consisting of fused pentagons located between sheets of [(cyclam)metal] moieties; the second one is an infinite string of composition {(H3O+)-(H2O)-(H3O+)-(H2O)-(H3O+)-(H2O)-(H3O+)}∞.
Chronic Visual Stimulation with LED Light Flickering at 24, 40, or 80 Hz Failed to Reduce Amyloid β Load in the 5XFAD Alzheimer’s Disease Mouse Model
Authors: Yang Ya Lan , Lai Ted Weita 
Published: August 2023

AbstractA single 1-h session (or 7 d of daily 1-h sessions) of noninvasive visual stimulation with LED light flickering at 40 Hz, but not at 20 or 80 Hz, was reported to increase microglial size and decrease amyloid β (Aβ) load in the 5xFAD mouse model of Alzheimer’s disease. To achieve better therapeutic benefits, we explored the effects of daily 1-h sessions of visual stimulation with continuous light or LED light flickering at 24, 40, or 80 Hz for a period of five weeks in 5xFAD mice. As expected, 33-week-old 5xFAD mice but not control wild-type mice of the same age exhibited an abundance of swollen microglia and Aβ plaques in the visual cortex and hippocampus. Unexpectedly, however, compared with similar session of stimulation with continuous light or a light flickering at 24 or 80 Hz, daily sessions of stimulation with LED light flickering at 40 Hz for five weeks failed to further increase the microglial size and could not noticeably decrease the Aβ load in the visual cortex and hippocampus of the 5xFAD mice. In conclusion, contrary to previous findings based on shorter treatment periods, our data showed that daily noninvasive exposure to a light flickering at 40 Hz for a period of five weeks is not effective in reducing Aβ load in the 5xFAD mouse model of Alzheimer’s disease.
Perturbed Information Processing Complexity in Experimental Epilepsy
Authors: Clawson Wesley , Waked Benjamin , Madec Tanguy , Ghestem Antoine , Quilichini Pascale P. , Battaglia Demian , Bernard Christophe 
Published: August 2023

Comorbidities, such as cognitive deficits, which often accompany epilepsies, constitute a basal state, while seizures are rare and transient events. This suggests that neural dynamics, in particular those supporting cognitive function, are altered in a permanent manner in epilepsy. Here, we test the hypothesis that primitive processes of information processing at the core of cognitive function (i.e., storage and sharing of information) are altered in the hippocampus and the entorhinal cortex in experimental epilepsy in adult, male Wistar rats. We find that information storage and sharing are organized into substates across the stereotypic states of slow and theta oscillations in both epilepsy and control conditions. However, their internal composition and organization through time are disrupted in epilepsy, partially losing brain state selectivity compared with controls, and shifting toward a regimen of disorder. We propose that the alteration of information processing at this algorithmic level of computation, the theoretical intermediate level between structure and function, may be a mechanism behind the emergent and widespread comorbidities associated with epilepsy, and perhaps other disorders.SIGNIFICANCE STATEMENTComorbidities, such as cognitive deficits, which often accompany epilepsies, constitute a basal state, while seizures are rare and transient events. This suggests that neural dynamics, in particular those supporting cognitive function, are altered in a permanent manner in epilepsy. Here, we show that basic processes of information processing at the core of cognitive function (i.e., storage and sharing of information) are altered in the hippocampus and the entorhinal cortex (two regions involved in memory processes) in experimental epilepsy. Such disruption of information processing at the algorithmic level itself could underlie the general performance impairments in epilepsy.
ADPGK‐AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth
Authors: Karger Annika , Mansouri Siavash , Leisegang Matthias S , Weigert Andreas , Günther Stefan , Kuenne Carsten , Wittig Ilka , Zukunft Sven , Klatt Stephan , Aliraj Blerina , Klotz Laura V , Winter Hauke , Mahavadi Poornima , Fleming Ingrid , Ruppert Clemens , Witte Biruta , Alkoudmani Ibrahim , Gattenlöhner Stefan , Grimminger Friedrich , Seeger Werner , Pullamsetti Soni Savai , Savai Rajkumar 
Published: August 2023

AbstractLong noncoding RNAs (lncRNAs) influence the transcription of gene networks in many cell types, but their role in tumor‐associated macrophages (TAMs) is still largely unknown. We found that the lncRNA ADPGK‐AS1 was substantially upregulated in artificially induced M2‐like human macrophages, macrophages exposed to lung cancer cells in vitro, and TAMs from human lung cancer tissue. ADPGK‐AS1 is partly located within mitochondria and binds to the mitochondrial ribosomal protein MRPL35. Overexpression of ADPGK‐AS1 in macrophages upregulates the tricarboxylic acid cycle and promotes mitochondrial fission, suggesting a phenotypic switch toward an M2‐like, tumor‐promoting cytokine release profile. Macrophage‐specific knockdown of ADPGK‐AS1 induces a metabolic and phenotypic switch (as judged by cytokine profile and production of reactive oxygen species) to a pro‐inflammatory tumor‐suppressive M1‐like state, inhibiting lung tumor growth in vitro in tumor cell‐macrophage cocultures, ex vivo in human tumor precision‐cut lung slices, and in vivo in mice. Silencing ADPGK‐AS1 in TAMs may thus offer a novel therapeutic strategy for lung cancer.
NME6: ribonucleotide salvage sustains mitochondrial transcription
Authors: Wanrooij Paulina H , Chabes Andrei 
Published: August 2023

The building blocks for RNA and DNA are made in the cytosol, meaning mitochondria depend on the import and salvage of ribonucleoside triphosphates (rNTPs) and deoxyribonucleoside triphosphates (dNTPs) for the synthesis of their own genetic material. While extensive research has focused on mitochondrial dNTP homeostasis due to its defects being associated with various mitochondrial DNA (mtDNA) depletion and deletion syndromes, the investigation of mitochondrial rNTP homeostasis has received relatively little attention. In this issue of the EMBO Journal, Grotehans et al provide compelling evidence of a major role for NME6, a mitochondrial nucleoside diphosphate kinase, in the conversion of pyrimidine ribonucleoside diphosphates into the corresponding triphosphates. These data also suggest a significant physiological role for NME6, as its absence results in the depletion of mitochondrial transcripts and destabilization of the electron transport chain (Grotehans et al, 2023).
Calculation of ATP production rates using the Seahorse XF Analyzer
Authors: Desousa Brandon R , Kim Kristen KO , Jones Anthony E , Ball Andréa B , Hsieh Wei Y , Swain Pamela , Morrow Danielle H , Brownstein Alexandra J , Ferrick David A , Shirihai Orian S , Neilson Andrew , Nathanson David A , Rogers George W , Dranka Brian P , Murphy Anne N , Affourtit Charles , Bensinger Steven J , Stiles Linsey , Romero Natalia , Divakaruni Ajit S 
Published: August 2023

AbstractOxidative phosphorylation and glycolysis are the dominant ATP‐generating pathways in mammalian metabolism. The balance between these two pathways is often shifted to execute cell‐specific functions in response to stimuli that promote activation, proliferation, or differentiation. However, measurement of these metabolic switches has remained mostly qualitative, making it difficult to discriminate between healthy, physiological changes in energy transduction or compensatory responses due to metabolic dysfunction. We therefore present a broadly applicable method to calculate ATP production rates from oxidative phosphorylation and glycolysis using Seahorse XF Analyzer data and empirical conversion factors. We quantify the bioenergetic changes observed during macrophage polarization as well as cancer cell adaptation to in vitro culture conditions. Additionally, we detect substantive changes in ATP utilization upon neuronal depolarization and T cell receptor activation that are not evident from steady‐state ATP measurements. This method generates a single readout that allows the direct comparison of ATP produced from oxidative phosphorylation and glycolysis in live cells. Additionally, the manuscript provides a framework for tailoring the calculations to specific cell systems or experimental conditions.
Effect of Safety Education to Workers Productivity at The Electric Welding Workshop
Authors: Fauzi Akmal , Assyifa Vania Bintang , Muhammad Khayla Diandra Fatima , Artanti Emilia Indri , Phuttharak Tharada , Himmah Irna Mufidatul 
Published: August 2023

Productivity is generally defined as a measure of the amount of output generated per unit of input. The aim of this research is to analyse the effect of the fulfilment of Occupational Safety and Health as well as the ability, experience, motivation, and discipline of workers on the probability of low productivity in the Electric Welding Workshop. The method used in this study was a qualitative descriptive method with questionnaires and observation sheets. The result showed that the Electric Welding Workshop workers felt that the fulfilment of OSH aspects, their ability, experience, motivation, and discipline impacted their productivity. The study concludes that Electric Welding Workshop is not included in low productivity because it produces stuffs with quality and quantity according to standards, although it has not yet fulfilled the aspects that increase productivity.
The effect of a short breathing intervention on postural control and heart rate variability
Authors: Sahebjamee N. , Nagy E. 
Published: August 2023

AbstractPurposeThe objective of this study was to determine the immediate effect of a short breathing intervention on postural control and heart rate variability in healthy individuals.Materials/MethodsThe study involved 28 participants. Heart rate variability and heart rate were measured using a Polar (H10) sensor, and the sway path during posturography was recorded using the NeuroCom system, with participants standing on a firm then a foam surface in the eyes open and eyes closed conditions. All measurements were performed before and after the breathing intervention to provide baseline and post-intervention data. A short breathing intervention was performed between testing to stimulate the autonomic nervous system. In the Wilcoxon matched pairs comparison using Statistica software, P < 0.05 was considered statistically significant.ResultsThe breathing intervention caused a significant decrease in heart rate variability and an increase in heart rate. In the eyes closed condition, on a firm surface, the breathing intervention significantly reduced the sway path.ConclusionsThe breathing intervention reduced the sway path in conditions without visual information but appeared to have no effect on balance in conditions with visual information, suggesting that the postural function of the diaphragm becomes more prominent in nonvisual conditions. We obtained evidence of the relationship between the autonomic nervous system and postural control. The stimulation of the sympathetic tone by means of the breathing intervention had a significant effect on postural control on firm and foam surfaces without visual information and decreased postural sway.
Parafoveal capillary density as a potential biomarker in the assessment of diabetic retinopathy progression
Authors: István L. , Nagy Z. Z. , Kovács I. 
Published: August 2023

AbstractPurposeThe aim of this study was to assess longitudinal changes in retinal vessel density in diabetic patients using optical coherence tomography angiography (OCTA) to identify the most sensitive parameter for detecting retinopathy progression.MethodsPatients with diabetes mellitus were enrolled in this study. Each study subject underwent two imaging sessions, during which three OCTA images of the macular area and three images of the optic nerve head were obtained. The two sessions took place one year apart. The OCTA imaging was performed using an AngioVue device. Superficial vessel density was evaluated in the central 3 mm and parafoveal area, and the nonflow area was measured using the built-in automated AngioAnalytics software of the Optovue system.ResultsThis study included 78 eyes of 39 diabetic patients (age: 55.16 ± 13.73 years) with a mean of 7.70 ± 1.07 mmol L−1 HgA1c level at baseline. At the one-year visit, the eyes of the diabetic subjects had significantly lower superficial vessel density in the parafoveal macula compared to corresponding values at baseline (p < 0.05). There was no statistically significant difference between the baseline and one-year results for the other vascular density parameters and the foveal avascular zone (p > 0.05).ConclusionAt the one-year follow-up, we found that vessel density had decreased in the parafoveal ring in these patients, while there was no significant change in other vascular parameters. This result suggests that superficial parafoveal capillary density is the most sensitive OCTA parameter that can be used as a biomarker for diabetic retinopathy progression. None of the other vascular density parameters nor the foveal avascular zone were able to indicate the subtle changes in retinal microcirculation due to the progression of diabetic microvasculopathy.
Aplikasi Pakan Mandiri Terhadap Performa Budidaya pada Pendederan Ikan Gurami (Osphronemus gouramy) di Deli Serdang, Sumatera Utara
Authors: Suharyadi Suharyadi , Nurhudah Mochammad , Br Tambunan Rezky Arie 
Published: August 2023

Ikan Gurami (Osphronemus gouramy) menjadi salah satu komoditas ikan air tawar yang banyak dibudidayakan oleh masyarakat dan menjadi unggulan karena memiliki nilai ekonomi penting dan banyak digemari masyarakat. Perlunya mendorong produksi ikan gurame yang tinggi guna memenuhi kebutuhan pasar juga harus dibarengi efisiensi biaya produksi agar harga bisa bersaing. Tujuan penelitian adalah mengevaluasi performa budidaya dengan pemberian pakan komersial dan pakan mandiri. Metode yang dilakukan yaitu mengurangi penggunaan pakan komersil dan menggantinya dengan pakan mandiri namun tetap menjaga formulasi pakan sesuai kebutuhan nutrisi ikan. Rancangan percobaan yaitu 2 perlakuan dan 4 ulangan. Padat tebar hewan uji 100 ekor/m3 ukuran 2-4 cm. Pengujian yang dilakukan adalah dengan T test (signifikan 0,05) yaitu membandingkan pertumbuhan ikan gurami yang diberi pakan komersial dan pakan mandiri dengan kandungan nutrisi yang telah disesuaikan. Pemberian pakan dengan menggunakan feeding rate 10% dari bobot ikan dan diberikan dua kali sehari pada jam 08.00 dan 17.00 WIB. Pemberian pakan dilakukan dalam waktu yang sama antara pakan komersial dan pakan mandiri. Terdapat perbedaan nyata dari pemberian pakan komersial dan menghasilkan nilai yang baik pada Average Body Weight (ABW) (4,57 ± 0,05), Pertumbuhan Panjang Mutlak (6,49 ± 0,09), Spesific Growth Rate (SGR) (15,44 ± 0,89) dan Survival Rate (SR) (17,75 ± 2,75). Pada benih yang diberi pakan mandiri diperoleh nilai Average Body Weight (ABW) (3,98 ± 0,11). Pertumbuhan panjang mutlak (5,74 ± 0,15) dan Survival rate (SR) (11,25 ± 1,26 %). Untuk mendapatkan pertumbuhan yang baik pada pemeliharaan ikan gurami maka dapat digunakan pakan komersial.