bluuebunny/crossref_metadata_2025_split huggingface dataset:
Achondroplasia Natural History Study (CLARITY): 60-year experience with hydrocephalus in achondroplasia from four skeletal dysplasia centers
Authors: Campbell Jeffrey , Legare Janet M. , Piatt Joseph , Gough Ethan , Pauli Richard M. , Hashmi S. Shahrukh , Rodriguez-Buritica David F. , Modaff Peggy , Little Mary Ellen , Serna Maria Elena , Smid Cory J. , Dujmusic Lorena , Hecht Jacqueline T. , Hoover-Fong Julie E. , Bober Michael B. 
Published: September 2023

OBJECTIVE
The objective of this study was to describe the incidence and management of hydrocephalus in patients with achondroplasia over a 60-year period at four skeletal dysplasia centers.

METHODS
The Achondroplasia Natural History Study (CLARITY) is a registry for clinical data from achondroplasia patients receiving treatment at four skeletal dysplasia centers in the US from 1957 to 2017. Data were entered and stored in a REDCap database and included surgeries with indications and complications, medical diagnoses, and radiographic information.

RESULTS
A total of 1374 patients with achondroplasia were included in this study. Of these, 123 (9%) patients underwent treatment of hydrocephalus at a median age of 14.4 months. There was considerable variation in the percentage of patients treated for hydrocephalus by center and decade of birth, ranging from 0% to 28%, although in the most recent decade, all centers treated less than 6% of their patients, with an average of 2.9% across all centers. Undergoing a cervicomedullary decompression (CMD) was a strong predictor for treatment of hydrocephalus (OR 5.8, 95% CI 3.9–8.4), although that association has disappeared in those born since 2010 (OR 1.1, 95% CI 0.2–5.7). In patients born since 1990, treatment of hydrocephalus with endoscopic third ventriculostomy (ETV) has become more common; it was used as the first line of treatment in 38% of patients in the most recent decade. Kaplan-Meier analysis suggests that a single ETV will treat hydrocephalus in roughly half of these patients.

CONCLUSIONS
While many children with achondroplasia have features of hydrocephalus with enlarged intracranial CSF spaces and relative macrocephaly, treatment of hydrocephalus in achondroplasia patients has become relatively uncommon in the last 20 years. Historically, there was a significant association between symptomatic foramen magnum stenosis and treatment of hydrocephalus, although concurrent treatment of both has fallen out of favor with the recognition that CMD alone will treat hydrocephalus in some patients. Despite good experimental data demonstrating that hydrocephalus in achondroplasia is best understood as communicating in nature, ETV appears to be reasonably successful in certain patients and should be considered an option in selected patients.
Model Konsep Hukum Ampere dan Penerapannya Untuk Menentukan Arus Listrik Di dalam Material-Material Semikonduktor
Authors: Ngaderman Hubertus , Sinaga Ego Srivajawaty 
Published: September 2023

Tujuan penelitian ini adalah memverifikasikan konsep hukum Ampere secara teoritis dan mengadopsi konsep tersebut guna mencari arus listrik di dalam divais-divais berbasis material semikonduktor. Metode yang digunakan di dalam penelitian ini adalah mengkaji secara teoritis konsep tentang hukum Ampere dan membuktikan hukum tersebut di dalam bahasa matematis, oleh karena itu dihadirkan piranti matematis yaitu operator del yang menjadikan divergensi dan curl di dalam usaha untuk membuktikan kebenaran hukum Ampere. Bukan hanya meninjau operator matematis, tetapi juga sedikit komputasi untuk menghitung arus listrik di dalam material semikonduktor dan dioda junction. Di dalam membuktikan ketiadaan arus listrik di dalam arah sejajar medan magnet material semikonduktor dan dioda junction, digunakan divergensi medan magnet. Untuk membuktikan adanya arus listrik di dalam material semikonduktor dan dioda junction, digunakan curl medan magnet.
Tinjauan Konseptual Vibrasi Molekul dan Mekanika Klasik Untuk Spektrofotometri Molekuler
Authors: Ngaderman Hubertus , Sinaga Ego Srivajawaty , Anou Kezia Noviani 
Published: September 2023

Tujuan dari penelitian ini, yang pertama adalah meninjau vibrasi antar molekul dengan melihat pada konsep mekanika klasik yaitu getaran antara dua partikel yang dihubungkan dengan pegas. Pegas disini diartikan sebagai sebuah benda mikroskopis yang mempunyai suatu konstanta pegas. Dan yang kedua adalah konstanta pegas dari molekul tersebut diketahui maka frekuensi getar akan didapat, sesudah itu energi vibrasi molekul diperoleh. Untuk mendapatkan spektra vibrasi molekul maka digunakan metode konsep mekanika klasik untuk menentukan massa reduksi, konstanta pegas , frekuensi . Mekanika kuantum digunakan untuk menentukan energi vibrasi molekul . Dari metode konsep diatas maka didapatkan besaran-besaran massa reduksi dan konstanta pegas , dimana besaran-besaran tersebut adalah parameter untuk menentukan energi vibrasi molekul untuk hidrogen dan natrium klorida .
E-LEARNING SATISFACTION ANALYSIS OF CLINICAL ROTATION NURSING STUDENTS
Authors: Harjanto Totok , Achmad Bayu Fandhi , Sumunar Dimas S. E. W. 
Published: September 2023

ABSTRACTObjective: To identify the learning satisfaction of clinical rotation nursing management students. Methods: A descriptive study took place in a class of clinical rotation nursing management. Participants were 22 female clinical rotation nursing student who were in the nursing management stage period September-October 2017. Eligible criteria for the students are voluntary participating in the research, fully engaged in the whole learning activities and following brief introduction and course evaluation. Research instrument is the form of learning satisfaction questionnaire developed by Center of Innovation and Academic Policy UGM. Validity test incorporate product moment resulting 13 valid items. 10 items required modification to meet the validity. Cronbach’s Alpha reliability test yields internal consistency value of 0.839. Data analyses were using frequency distribution with means considered as cutoff point. Results: Clinical rotation nursing students have a similar learning satisfaction between high and low (50%: 50%). Discussion: Based on 4 attributes of the questionnaire, the majority of respondents have high satisfaction on the aspect of online assignment (54.5%), aspect of online lecture materials and eLearning facilities have the same satisfaction (50%: 50%) and the online discussion aspect of the majority of respondents have low satisfaction (54.5 %). Conclusion: Clinical rotation students in nursing management show the same level of satisfaction between high and low on e-learning. Development of learning media and electronic learning delivery methods required to value the benefits in the future.Keywords: clinical rotation; e-learning; nursing student; students’ satisfaction.
Effect of Top Management Team Characteristics and Green Innovation on Firm Performance in Indonesia: Role of Carbon Emission Disclosure
Authors: Tjahjadi Bambang , Soewarno Noorlailie , Kamarudin Khairul Anuar , Aldina Sazkiya , Karima Tsanya El , Sutarsa Annisa Ayu Putri 
Published: September 2023

The purpose of this study is to investigate whether top management team (TMT) characteristics and green innovation (GI) affect firm performance, and if so, whether the effect is mediated by carbon emission disclosure (CED). This quantitative study employs the partial least square structural equation modeling (PLS-SEM) to test the hypotheses. The data were collected from the high-profile companies listed in the Indonesia Stock Exchange (IDX) for the 2015 - 2019 period. A mediating research framework was developed to explain the association among constructs. Using agency theory and sustainability theory (triple bottom line), the results show the following findings. First, TMT characteristics positively affect firm performance. Second, GI positively affects on firm performance. Third, CED partially mediates the effect of TMT characteristics on firm performance. Fourth, CED partially mediates the effect of GI on firm performance. The current study addresses the existing research gaps and debates in the previous studies in term of proposing a more comprehensive framework by adding CED as a mediating variable. This study also builds a new dataset and focuses on environmental issues in the Indonesian research setting as an emerging country and a two-tier governance system adopter.
A GARCH Model to Understand the Volatility of the Electricity Spot Price in Brazil
Authors: Da Silva Leite André Luis , Andrade de Lima Marcus Vinicius 
Published: September 2023

Electricity is sensitive to extreme price events and spot price volatility is an inherent characteristic of competitive electricity markets. The purpose of this article it to model the realized volatility of electricity spot price in Brazil. The Brazilian electricity industry presents unique characteristics and because of this price varies a lot in a short period. So, we developed a GARCH model using 862 weekly observations to understand the realized volatility in the four different market. We conclude that the spot price in Brazil presents high volatility that presents risk to agents. This high volatility is associated with institutional factors and the increase in the share of renewable energy in the electricity mix.
Demographic, Clinical, and Tumor Profile Of Meningioma In Mohammad Hoesin Hospital Palembang, Indonesia
Authors: Anggraeni Dya , Diansari Yunni , Hafy Zen 
Published: September 2023

Introduction. Meningioma was the most frequently reported primary intracranial tumor. There had been a few reports about meningioma profile in Indonesia. The objective of this study is to identify the profile of meningioma based on demographic, clinical, and tumor characteristics.
Methods. This is a cross-sectional study using secondary data from medical records. There were 67 meningioma patients based on histopathological examination at Mohammad Hoesin Hospital from January to December 2018. Various data were recorded, including demografic profile, history of hormonal contraceptive use, neurologic symptoms, and tumor characteristic.
Results. During 2018, the incidence of meningioma was 68,3% of all primary CNS tumors. Meningioma was mostly found in the age group 35-44 years (44.8%). Most of the patients was female (92.5%) and 29 patients (46.8%) had a history of hormonal contraceptive use. Headache showed the highest rate of clinical manifestation in meningioma patient (34.3%). Based on the location, convexity meningioma was the most frequently found (65.7%). Of the 67 meningioma patients, only 26 datas were obtained regarding a history of radiation exposure and all without a history of radiation. There was only one patient (1.5%) with a family history of malignancy (breast tumor). Based on histopathological examination, 60 patients (89.6%) reported as WHO grade I, mostly the meningothelial subtype (40%). The outcome was generally good in most patients (88.1%).
Conclusion. In our institution, meningioma is the most commonly found primary brain tumor. Headache was the most common clinical manifestation and these tumors were mostly located in convexity of the brain, with the majority being WHO grade I and meningothelial subtype.
In-silico Analysis Of Maricaffeoylide From Avicennia Marina Using Molecular Docking With Tumor Necrosis Factor Receptor
Authors: Setiyabudi Lulu , Ulya Nila Fadila , Indratmoko Septiana , Swandari Mika Tri Kumala 
Published: September 2023

Introduction. Bioactive metabolites was isolated from Avicennia marina fruit belongs to a new caffeoyl derivative, maricaffeoylide. It was a class of phenolic compounds such as caffeic acid which had potential as anticancer, anti-inflammatory, and antioxidant activity. One of proinflammatory cytokine that play a role in regulating immune cells against cancer is TNF-α. In-silico analysis is often used to molecular docking. It was carried out to determine the interaction molecule between bioactive compound and receptor. The purpose of this study is to analysed of interaction maricaffeoylide and TNF-α receptor using molecular docking. In this study, molecular docking will be carried out to determine the interaction and affinity of the bond energy.
Methods. The method used in this research is experimental which is carried out in silico using molecular docking. Maricaffeoylide was prepared by using Marvin Sketch and TNF-α receptor was downloaded from pdb. Molecular docking was carried out ligand and receptor preparation, validation, molecular tethering using Pyrx-Autodock Vina, and visualization by BIOVIA.
Result. The result of the conformation of the maricaffeoylide has an energy of 69.77 kcal/mol. The gridbox is adjusted at center coordinates x = 14.85; y = -6.50; and z = -6.70 and at dimensions x = 31, y = 35, and z = 63 Ǻ. The Lipinski’s rule for drug-likeness was confirmed.
Conclusion. Molecular docking of maricaffeoylide against TNF-α receptors was successfully performed with a docking score of -6.1 kcal/mol involving the interaction van der Waals, hydrogen, alkyl, and carbon hydrogen.
Reflux Symptom Index And Reflux Finding Score Correlation With Quality Of Life Of Laryngopharyngeal Reflux Patients
Authors: Yanti Lisa Apri , Mandela Rama , Bahar Erial 
Published: September 2023

Introduction. Laryngopharyngeal reflux (LPR) usually occurs due to the effects of reflux on the gloves and vocal cords. Symptoms range from more common symptoms such as hoarseness, globus sensations, and a feeling of getting stuck in the throat to less common symptoms such as heartburn and regurgitation. Symptoms common to LPR are not specific and may be related to other diseases. In other words, it is difficult to diagnose LPR based solely on symptoms. Belafsky et al in 2001 and 2002 developed the Reflux Symptom Index (RSI) and Reflux Finding Score (RFS) to assist in the diagnosis of LPR. Health-related quality of life Health-Related Quality of Life (HRQOL) in LPR patients have a negative impact on psychological status, social functioning, and quality of life. Symptoms of reflux appear to be a major contributor to the decline in quality of life. LPR patients have a significant impact on the mental component of their HRQO.
Methods. Descriptive research with a correlation test design, conducted at RSUP Dr. Mohammad Hoesin Palembang on 22 samples of LPR patients who were treated at ENTKL polyclinics, IGD, or consulted from other departments in July-August 2022.
Results. The majority of the study were women (81.85%) with dominant in the age group of 31-45 years (45.5%) with an average age of 42.23±11.88 years and a range of 19-66 years. There is a strong correlation between RSI and RFS with quality of life (r = 0.615; p = 0.016, r = 0.635; p = 0.028, respectively).
Conclusion. RSI and RFS are significantly related to the quality of life of the sample so the treatment is recommended to also focus on the LPR only but also the mental health aspects.
PERANAN STATISTICAL QUALITY CONTROL (SQC) DALAM PENGENDALIAN KUALITAS: STUDI LITERATUR
Authors: Syarifah Nazia  , Safrizal  , Muhammad Fuad  
Published: September 2023

This research is a literature study with descriptive qualitative research using literature review which describes the role of Statistical Quality Control in Quality Control. This research uses various sources such as journals, articles, and relevant documents. This literature study focuses on the Role of Statistical Quality Control in Quality Control. Companies really need supervision in each production process, so that companies can know the quality of the products produced. With a quality product, the company will benefit due to increased sales volume and of course it will make consumers feel more satisfied and can avoid complaints from customers after buying or using the product. SQC is a problem-solving tool used in monitoring, analyzing, improving, controlling and managing products in the process of using statistical methods. The SQC method can be used to find errors in the production process that are caused by product defects or damage, so that more action can be taken to overcome problems that cause product damage
Key Words: Quality, Control Quality, SQC
PENGARUH KEPUASAN KERJA DAN KOMITMEN ORGANISASI TERHADAP TURNOVER INTENTION DENGAN PERSON ORGANIZATION FIT SEBAGAI VARIABEL MODERASI
Authors: Pratama Eko Nur , Suwarni Emi , Handayani Maidiana Astuti 
Published: September 2023

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh kepuasan kerja dan komitmen organisasi terhadap turnover intention dengan person organization fit sebagai variabel moderasi pada karyawan PT Febri Dharma Mandiri. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif. Dalam penelitian ini data dikumpulkan dengan menggunakan kuisioner sebanyak 123 responden. Dengan mengurangi data outlier maka jumlah data yang dapat diolah sebanyak 109 data. Analisis data menggunakan analisis regresi linier berganda dan Moderated Regression Anlysis (MRA). Hasil analisis regresi linier berganda menunjukkan bahwa kepuasan kerja dan komitmen organisasi secara parsial berpengaruh negatif dan signifikan terhadap turnover intention. Moderated Regression Anlysis (MRA) menunjukkan bahwa Person organization fit tidak mampu memoderasi kepuasan kerja terhadap turnover intention, sedangkan Person organization fit mampu memoderasi komitmen organisasi terhadap turnover intention.
The Student Empathy for a Prospective School Counselor : How Does Group Counseling Affect It? (An Analysis Based on Gender)
Authors: Nuraeni Nuraeni , Suranata Kadek 
Published: September 2023

This study aims to analyze the effect of group counseling on increasing the empathy of prospective counselor students. The research method uses an experimental one-group pretest-posttest control design. The subjects in this study were guidance and counselling students at the Mandalika University of Education, and classified as having low empathy criteria. Data collection was carried out using an empathy questionnaire. Data analysis used the one-way ANOVA statistical test. The results of this study indicate that group counselling affects increasing the empathy of guidance and counselling students at the Mandalika University of Education. Besides there are differences in the level of empathy between male and female students, where female students have higher empathy than male students.
Logística versus Administração: Uma análise comparativa e integrada
Authors: Ferigato Evandro , Santos Osmildo Sobral dos , Souza Suzy Mary Nunes Lopes de , Messias José Flavio , Lima Douglas Leonardo de , Estender Antônio Carlos 
Published: September 2023

Este artigo tem como objetivo investigar a relação entre logística e administração que é um tema de grande relevância para a gestão empresarial contemporânea. Ambas as áreas desempenham papéis fundamentais no funcionamento eficiente das organizações, porém, suas abordagens e enfoques podem apresentar diferenças significativas. Neste artigo, discutiremos a relação entre logística e administração, explorando as possíveis interações, sinergias e desafios existentes nesse contexto. Para atender a proposta citada, delineou-se a seguinte questão de pesquisa: o que tem sido produzido sobre Logística versus Administração: Uma Análise Comparativa e Integrada. Os principais resultados destacam a importância da integração eficiente da logística e administração para o sucesso das organizações, enfatizando a necessidade de uma abordagem colaborativa e estratégica. O artigo é elaborado de forma estruturada, apresentando uma revisão dos conceitos-chave entre logística e administração. Assim, trata-se de uma revisão narrativa da literatura. O levantamento dos artigos foi realizado nas seguintes bases de dados: Scopus e Google Scholar e Web of Science. No total, 157 artigos foram encontrados e 20 foram selecionados para análise de conteúdo temática, de acordo com os critérios de inclusão e exclusão. A conclusão recapitula os principais achados da pesquisa, enfatizando a importância da integração entre logística e administração para o sucesso organizacional. Sugere-se que pesquisas futuras explorem os temas abordados para uma compreensão mais aprofundada.
The phenotypic and genetic features of arrhythmogenic cardiomyopathy in the pediatric population
Authors: Kofeynikova Olga , Alekseeva Daria , Vershinina Tatiana , Fetisova Svetlana , Peregudina Olga , Kovalchuk Tatiana , Yakovleva Elena , Sokolnikova Polina , Klyushina Alexandra , Chueva Kseniia , Kostareva Anna , Pervunina Tatiana , Vasichkina Elena 
Published: September 2023

IntroductionThe present study aimed to describe the phenotypic features and genetic spectrum of arrhythmogenic cardiomyopathy (ACM) presented in childhood and test the validity of different diagnostic approaches using Task Force Criteria 2010 (TFC) and recently proposed Padua criteria.Patients and methodsThirteen patients (mean age at diagnosis 13.6 ± 3.7 years) were enrolled using “definite” or “borderline” diagnostic criteria of ACM according to the TFC 2010 and the Padua criteria in patients &lt;18 years old. Clinical data, including family history, 12-lead electrocardiogram (ECG), signal-averaged ECG, 24-h Holter monitoring, imaging techniques, genetic testing, and other relevant information, were collected.ResultsAll patients were classified into three variants: ACM of right ventricle (ACM-RV; n = 6, 46.1%), biventricular ACM (ACM-BV; n = 3, 23.1%), and ACM of left ventricle (ACM-LV; n = 4, 30.8%). The most common symptoms at presentations were syncope (n = 6; 46.1%) and palpitations (n = 5; 38.5%). All patients had more than 500 premature ventricular contractions per day. Ventricular tachycardia was reported in 10 patients (76.9%), and right ventricular dilatation was registered in 8 patients (61.5%). An implantable cardiac defibrillator was implanted in 61.5% of cases, and three patients with biventricular involvement underwent heart transplantation. Desmosomal mutations were identified in 8 children (53.8%), including four patients with PKP2 variants, two with DSP variants, one with DSG2 variant, and one with JUP. Four patients carried compound heterozygous variants in desmosomal genes associated with left ventricular involvement.ConclusionArrhythmias and structural heart disease, such as chamber dilatation, should raise suspicion of different ACM phenotypes. Diagnosis of ACM might be difficult in pediatric patients, especially for ACM-LV and ACM-BV forms. Our study confirmed that using “Padua criteria” in combination with genetic testing improves the diagnostic accuracy of ACM in children.