bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computer-based analysis of the taper connection strength of different revision head and adapter sleeve designs
Authors: Meier Johanna , Hembus Jessica , Bader Rainer , Vogel Danny 
Published: September 2023

Abstract

Objectives
Ceramic revision heads, equipped with titanium adapter sleeves, are used in femoral head revision in total hip arthroplasty to avoid ceramic fracture due to the damaged taper.

Methods
A finite element analysis of the taper connection strength of revision heads with varying head diameters combined with adapter sleeves of different lengths was conducted. The influence of various assembly forces, head diameter, and length of the adapter sleeves was evaluated. For two combinations, the pattern of contact pressure was evaluated when applying a simplified joint load (3 kN, 45° load angle). Experimental validation was conducted with 36 mm heads and adapter sleeves in size S, as well as 28 mm heads and adapter sleeves in size XL.

Results
The pull-off force increased with higher assembly forces. Using larger head diameters and adapter sleeves led to decreased pull-off forces, a reduced contact surface, and less contact pressure. The contact pressure showed significant peaks and a diagonal pattern under 45° angle loading when assembly forces were less than 4 kN, and larger adapter sleeves were utilized.

Conclusion
A sufficient assembly force should be ensured intraoperatively, especially with an increasing head diameter and adapter sleeve size, as lower assembly forces might lead to reduced taper connection strength.
Effects of a full-body electrostimulation garment application in a cohort of subjects with cerebral palsy, multiple sclerosis, and stroke on upper motor neuron syndrome symptoms
Authors: Hahn Andreas , Moeller Susan , Schlausch Arne , Ekmann Matilda , de Chelle Gautier , Westerlund Marie , Braatz Frank , Mayr Winfried 
Published: September 2023

Abstract

Objectives
Dysfunction of the central nervous system may inflict spastic movement disorder (SMD). Electrical stimuli were identified as promising therapeutic option. Electrical stimulation provided by a 58-electrode full body garment was investigated based on data from regular trial fittings.

Methods
Data from 72 testees were investigated. Age averages 36.6 (19.8) ys with 44 females. The cohort spans infantile cerebral paresis (CP) (n=29), multiple sclerosis (MS) (n=23) and stroke (n=20). Data were stratified by etiology and an entry BBS Score<45.

Results
Effect sizes (Cohen`s d) related BBS, TUG, FGA, 10mWT, WMFT, EQ5D5L and Pain. Significance levels are indicated by *: p<0.05, **: p<0.01, ***: p<0.001, (t): p<0.1: CP: 1.64***, 0.29*, 1.59***, 0.76(t), 1.00***, 0.5*, 1.28***; MS: 1.83***, 0.83***, 1.28**, 1.07***, 0.93*, 1,11**, 0.78*; Stroke: 1.28**, 0.78**, 0.89, 0.92**, 0.71, 1.26*, 0.78*.

Conclusions
Multi-site transcutaneous electrical stimulation may increase ambulation related skills in subjects with SMD stemming from CP, MS and stroke. The results indicate effects on static and dynamic balance, fall risk, mobility, upper extremity improvement and an overall increase in health utility and a reduction in spasticity related pain. Effects are immediate as well as sustained. These results may inspire individual trial fittings and inform further controlled trials.
Documenting and validating metrological traceability of serum alanine aminotransferase measurements: a priority for medical laboratory community for providing high quality service in hepatology
Authors: Panteghini Mauro 
Published: September 2023

Abstract
Alanine aminotransferase (ALT) represents the first-level test to detect individuals with hepatocellular damage of any etiology. However, it has been highlighted that the lack of assay harmonization may lead to overdiagnosis and unnecessary further testing if guideline-recommended fixed cut-offs are uncritically employed. To solve the issue of ALT (dis)harmonization and improve the interpretation of its values, a series of urgent actions for documenting and validating metrological traceability of serum ALT measurements, as described in this paper, are no longer postponeable. It is time that all medical laboratory stakeholders (in vitro diagnostic manufacturers, laboratorians, external quality assessment scheme organizers) actively co-operate to implement the ALT standardization in a concerted action following well-established theoretical assumptions and applying experimental approaches described in literature.
Diurnal temperature variation and the implications for diagnosis and infectious disease screening: a population-based study
Authors: Miller Aaron C. , Koeneman Scott H. , Suneja Manish , Cavanaugh Joseph E. , Polgreen Philip M. 
Published: September 2023

Abstract

Objectives
Fevers have been used as a marker of disease for hundreds of years and are frequently used for disease screening. However, body temperature varies over the course of a day and across individual characteristics; such variation may limit the detection of febrile episodes complicating the diagnostic process. Our objective was to describe individual variation in diurnal temperature patterns during episodes of febrile activity using millions of recorded temperatures and evaluate the probability of recording a fever by sex and for different age groups.

Methods
We use timestamped deidentified temperature readings from thermometers across the US to construct illness episodes where continuous periods of activity in a single user included a febrile reading. We model the mean temperature recorded and probability of registering a fever across the course of a day using sinusoidal regression models while accounting for user age and sex. We then estimate the probability of recording a fever by time of day for children, working-age adults, and older adults.

Results
We find wide variation in body temperatures over the course of a day and across individual characteristics. The diurnal temperature pattern differed between men and women, and average temperatures declined for older age groups. The likelihood of detecting a fever varied widely by the time of day and by an individual’s age or sex.

Conclusions
Time of day and demographics should be considered when using body temperatures for diagnostic or screening purposes. Our results demonstrate the importance of follow-up thermometry readings if infectious diseases are suspected.
Postdemokratie als Krisendiagnose
Authors: Kersting Daniel 
Published: September 2023

AbstractThe article looks into the critical potential, but also the limits of the current discussion on post-democracy and the crisis of democracy and proposes an examination of the concept of crisis. The thesis is that the current talk of a crisis of democracy suggests an uncritical, namely restitutive understanding of the crisis that could be appropriated for an apology of Western liberal democracy. In contrast, the text argues for a renewed focus on the self-reflexive and critical potential of the term. Based on a pragmatist concept of problem and action, “crisis” is defined as a certain kind of problem-solving problem and further determined on the basis of four criteria. The contribution this definition makes to the current debate is shown by the example of Jacques Rancière’s diagnosis of post-democracy, which can be read as a diagnosis of crisis in the defined self-reflexive and critical sense.
The hybrid pulse amplitude width modulation scheme: high efficiency technique for dimmable VLC systems
Authors: El Jbari Mohamed , Moussaoui Mohamed 
Published: September 2023

Abstract
Visible-light communications (VLC) is an environmentally friendly optical wireless communication (OWC) technology that operates in the 400–800 THz frequency band. It is currently a critical technology for 5G and 6G wireless indoor applications due to its high data rates, low latency, and superior reliability. Intensity modulated direct detection (IM/DD) is widely used in VLC systems. A channel modulation scheme is designed using L-level pulse modulation techniques such as on–off keying (OOK), amplitude modulation (PAM), position modulation (PPM), and the width modulation (PWM). We introduce a novel hybrid modulation scheme n-M-PAWM based on both PAM and PWM schemes to improve throughput and significantly increase power and spectrum efficiency in VLC communication systems. The performance of our proposed hybrid n-M-PAWM scheme is studied in several aspects, including the number of transmitted bits per symbol, average BER, information rate ratio (IRR), PAPR, bandwidth, and power requirement. In an extremely noisy VLC system, the proposed 2-M-PAWM modulation outperforms both PPWM and PAPM modulation schemes due to its better BER performances. Additionally, we examine the performance of the VLC system in terms of spectral efficiency (SE) using our proposed PAWM-based dimming control system by varying the number of pulses transmitted during one symbol period. We demonstrate through simulation results that our PAWM-based dimming control system performs significantly better compared to the other pulse modulation schemes. All results of this research show that our proposed hybrid PAWM modulation scheme has high potential for VLC technology in indoor and noisy environments.
Clinical analysis of AN69ST membrane continuous venous hemofiltration in the treatment of severe sepsis
Authors: Gao Yuqiang , Huang Xiaohong , Yang Yanan , Lei Zhenlin , Chen Qingan , Guo Xu , Tian Jia , Gao Xiaoxin 
Published: September 2023

Abstract
We aimed to investigate the clinical efficacy of blood purification technology based on cytokine adsorption in the treatment of sepsis. Sixty patients with sepsis were randomly divided into control (n = 30) and experimental (n = 30) groups. Both groups were given routine treatment and continuous venovenous hemofiltration, and on this basis, the experimental group received acrylonitrile/sodium methacrylate (AN69ST) blood purification. The levels of C-reactive protein, procalcitonin, white blood cell count, albumin, platelets, total bilirubin, creatinine, lactic acid, and APACE II score, as well as secretion of inflammatory factors interleukin (IL)-6 and tumor necrosis factor (TNF-α) were compared. The hospitalization time, mechanical ventilation (MV) time, drug use time, and mortality were analyzed. After treatment, the secretion levels of IL-6 and TNF-α were decreased, and other indicators were significantly improved compared with those before treatment (P < 0.05), especially in the experimental group (P < 0.05). The hospitalization time, MV time, and drug use time in the experimental group were significantly lower than those of the control group (P < 0.05), and the mortality was lower than that in the control group (P < 0.05). In conclusion, blood purification technology based on cytokine adsorption can significantly improve various indicators of sepsis patients, reduce hospitalization time, reduce mortality, and improve the prognosis.
Effects of infill patterns and densities on crack propagation behavior in additive manufactured parts: a comparative study
Authors: Arikan Volkan 
Published: September 2023

Abstract
This study investigates the influence of infill patterns and densities on crack propagation behavior in additive manufactured parts. Through three-point bending tests, force–displacement data were obtained for specimens with different infill patterns, densities, and crack sizes. The results demonstrate that infill density significantly affects the mechanical properties and fracture characteristics of the parts. Higher infill densities result in increased strength but reduced tolerance for deformation, leading to a more abrupt failure mode. The findings highlight the importance of carefully selecting the infill pattern and density to optimize the mechanical performance of 3D-printed parts. Understanding these relationships is crucial for designing robust and reliable structures for various applications in additive manufacturing.
Stabilization of Soft Clay with Sustainable Binders for Dry Deep Mixing Design
Authors: López Ramírez Alejandra , Zhang Yinning , Forsman Juha , Korkiala-Tanttu Leena 
Published: September 2023

Abstract
Dry deep mixing (DDM) is a soil stabilization method widely used in countries with large soft clay areas, such as in the Nordic countries. In Finland, DDM is performed using a binder material that commonly consists of cement and lime in a 50:50 or 30:70 ratio. However, both lime and cement generate large amounts of emissions of carbon dioxide, which has led to a shift toward alternative materials in recent years. This paper presents the results of an extensive testing program where samples of Finnish sensitive soft clay are stabilized with eight different low emissions binders and tested by means of the uniaxial compression strength test. The alternative binders comprise different by-products and/or pozzolanas in varied percentages, which include lime kiln dust (LKD), biomass-based fly ash from bioenergy production, gypsum, blast furnace slag, as well as lime and cement in reduced amounts. The tests were performed on samples stabilized at different binder densities (60, 70, 100, 120, 140, and 160 kg/m3) and after 28 days of curing to determine the optimum densities for DDM design purposes. The results showed that binders such as blast furnace cement, the cement- quicklime-gypsum (33:33:33), and the LKD-cement (50:50) exhibited higher strength than the traditional lime/cement binders at different binder densities. In addition to these results, a simplified CO2 emissions calculation procedure is proposed for a DDM design supporting a road embankment, and two different emissions factors are obtained for the investigated binders. The results showed that some alternative binders can provide high binding efficiency with low CO2 emissions.
An abnormal LPA/LPAR1–NHE1 axis leads to the autophagy deficiency of trophoblast cells in recurrent spontaneous abortion
Authors: Chen Min , Shi Jia-Lu , Zheng Zi-Meng , Lin Zhi , Li Ming-Qing , Shao Jun 
Published: September 2023

In brief
Autophagy is important for trophoblast cells at the maternal–fetal interface during early pregnancy. This study suggests that trophoblast cells can promote the autophagy under a regulation of the LPA/LPAR 1–NHE1 axis.

Abstract
The autophagy of trophoblasts is necessary for developing and maintaining a healthy pregnancy. Autophagy dysfunction in trophoblast cells is linked to recurrent spontaneous abortion (RSA). However, the mechanism underlying trophoblast autophagy is unknown. In this study, we investigated the expression of autophagy-related genes in both normal and RSA villi. We also examined the production of LPA and LPAR1 in trophoblast cells during early pregnancy. We found that the activation of the LPA–LPAR1 axis triggered the autophagy of trophoblast cells and increased the expression of NHE1. Inhibition of NHE1 suppressed the autophagy in trophoblast cells and we confirmed that NHE1 regulates LPA production in trophoblast cells. Additionally, we found decreased expression of autophagy-related genes and LPAR1 in villi from RSA patients. These observations indicate that the LPA/LPAR1–NHE1 axis regulates the autophagy of trophoblast cells during pregnancy. Insufficient autophagy and poor expression of LPAR1 in trophoblast cells may result in the dysfunction of the trophoblasts and an increased risk of spontaneous abortion. Overall, our research elucidated that a positive LPA/LPAR1–NHE1 axis can promote the autophagy of trophoblast cells and the abnormal axis leads to the autophagy deficiency of trophoblast cells in recurrent spontaneous abortion.
Desarrollando el aula nuevo humanista: mediaciones pedagógicas para fomentar el pensamiento crítico
Authors: Baraona Cockerell Miguel , Sancho Ugalde María , Fallas Monge Johnny 
Published: September 2023

This article presents in a summary some pedagogical principles and educational practices for the development of the teaching experience within theframe of what we term as the new humanistic classroom, whether be it physical and/or virtual. This text begins with a very brief presentation of our understanding of humanism, New Humanism, The Tri Dimensional Paradigm (TDP), of New Humanism, in order to address in a summarized way, the 14pedagogical principles (14 PPS) of New Humanism derived from the TDP, which promote on a daily basis critical.
Los Mapas de Competencias: Una Herramienta para mejorar la Calidad de la Formación Universitaria
Authors: García SanPedro María José , Gairín Sallán Joaquín 
Published: September 2023

Los mapas de competencias se presentan como una herramienta necesaria para la formación y la evaluación en la Educación Superior. Pueden considerarse como una estrategia para favorecer la transparencia, la comunicación de resultados y el desarrollo organizativo. Este trabajo describe los resultados de un Estudio de 12 Casos en España. Se revisan los fundamentos, posibilidades y dificultades del trazado de los mapas como herramienta para mejorar la calidad, así como también los diversos enfoques que se aplican actualmente para adoptar las directrices del Proceso de Bolonia. Los resultados resaltan la complejidad que se asocia al trazado de los mapas de competencias y destacan la necesidad de implantar procesos más participativos para favorecer la responsabilidad colegiada sobre el desarrollo y la evaluación de las competencias.
Особливості функціонування українського медіаринку на тлі світового (2022 р. — перше півріччя 2023 р.)
Authors: Hotsur Oksana , Lozynskyi Marian 
Published: September 2023

У науковій розвідці здійснено аналіз стану медіаринку в Україні у контексті світового медіаринку. Зауважено, що сучасний кризовий період розвитку українських медіа пов’язаний як з внутрішньодержавними подіями, так зі світовими. Тут мова не тільки про російсько-українську війну з лютого 2022 р., але й про пандемію COVID-19, наслідки якого світова економіка переживає до сьогодні. Війна обумовила нову конфігурацію масмедійного ринку України, на якому змогли втриматися не всі традиційні медіа (газети та журнали, телеканали, радіо) та потужні медіагрупи, наприклад, «Медіа Група Україна».
Визначено специфіку загального стану медіаринку, відстежено зміни та певні характеристики його розвитку в умовах російсько-української війни та загальної світової економіки. Звернено увагу на роль соціальних мереж та інтернет-медіа в загальній конфігурації інформаційного ринку. При аналізі кожного сегмента медіаринку, а саме ринку друкованих ЗМІ, радіо- і телемовлення, ринку реклами та онлайн-медіа виявлено певні труднощі в їх розвитку. Так, ринок друкованих медіа програє іншим ринкам за фінансовими показниками, адже не витримує конкуренції з іншими видами ЗМІ. Але він досить успішно адаптується через застосування власних онлайн-версій та сервісів. Ринок друкованих медіа та ринок онлайн-медіа тісно перетинаються. Важливо, що в Україні, орієнтуючись на європейське правове регулювання, ухвалили закон «Про медіа». Також із ринком онлайн-медіа перетинаються інші два ринки — реклами та радіо- і телемовлення, що відповідає світовій тенденції. Стосовно України, то в 2022 р. відбулося скорочення радіо- і телемовників. Ринок реклами лише в цьому році зможе вийти на довоєнні показники. На сьогодні ж функціонує реклама відомих брендів та бренди фармацевтичного бізнесу.
У розвідці також звернено увагу на штучний інтелект, який уже змінює практичну журналістику (його застосовують у написанні новин, сценаріїв, створенні відео, анімації тощо), а згодом, на нашу думку, вплине на журналістську освіту.
Confessional pilgrimage in Ukraine and Germany as a social and communication interaction in the context of modern transformations
Authors: Panchenko Svitlana 
Published: September 2023

The article emphasizes that confessional pilgrimage as a social and communicative interaction in the context of modern transformations includes new approaches in Ukraine and Germany. The author describes pilgrimage trips to the cities and villages of Transcarpathia and Bavaria, taking into account the specifics of the routes and socio-communication features. Ukraine should be able to attract foreign and domestic tourists with its historical heritage. In addition, all monuments should be restored in accordance with the relevant programs and laws and be able to be maintained, developed and maintained at the expense of tourists. In addition, it should always be remembered that everything starts with culture in general and the attitude towards cultural monuments in particular. It is important to respect both the educational and cultural heritage of the country, and especially in times of war.
Pilgrimage guidebooks, as well as specialized, documentary, and feature films on relevant topics, stories, and interviews with other pilgrims about making sacred journeys, are of great importance for making a pilgrimage. Therefore, writing a guidebook is appropriate from the point of view of social communication, and it is in this plane that the author tries to reveal the significance of this means of communication through the collection of information, analysis of sources, visits to sacred places, photos, and videos. The development of a guide to pilgrimage sites in the cities and villages of Transcarpathia, as well as cities and villages of Bavaria, is a necessary part of the author's educational research.
The article uses cultural, comparative, and religious studies methods, which allowed the author to analyze issues of religious tourism, pilgrimage taking into account the specifics of this sphere. The author also used historical, systemic and informational approaches.
Information and communication activities and analytics during the Russian-Ukrainian war (on the example of social networks)
Authors: Afanasiev Illia , Novokhatko Leonid , Sinko Andrii 
Published: September 2023

The article analyzes the importance of information and communication activities during the war. In particular, it is determined that today there is a battle between Ukraine and the Russian Federation for a narrative, where both countries are looking for legitimacy and success in spreading correct information for themselves, because the perception of these narratives directly affects the course of hostilities. The article outlines the main narratives promoted by Ukraine and Russia.
The research hypothesis is that the world's first war of social networks is taking place in Ukraine. The interdependence between the spread of the mobile Internet, access to modern gadgets and the activity of propaganda activities in social networks is analyzed.
The main attention in intelligence is paid to the Internet as one of the most influential channels of communication, which is capable of reaching the maximum number of recipients in the shortest possible time, who then distribute the necessary information independently. The article proves that it is social networks that contain a large share of disinformation, which is "thrown in" by information scraps and fake pages. It is noted that fake or untrue content has a much higher chance of spreading than true information.
The article reveals the communication and technological specificity of the Internet environment in terms of propaganda influence, for which even the leading Ukrainian broadcasters (STUDIYA "1+1", "UA: First", "Rada", "ICTV", "STB" and "Ukraine 24 ") united in the joint telethon "Edyni Novyni" to show the official position of the state, sometimes use unverified information from the Internet and, accordingly, resort to spreading fakes or disinformation. In this context, the activity of the single news marathon against the background of the single information pool of Russia, which is under the control of the Kremlin, is analyzed.