bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of TaGL1‐B1 gene controlling grain length through regulation of jasmonic acid in common wheat
Authors: Niaz Mohsin , Zhang Lingran , Lv Guoguo , Hu Huiting , Yang Xi , Cheng Yongzhen , Zheng Yueting , Zhang Bingyang , Yan Xiangning , Htun Aye , Zhao Lei , Sun Congwei , Zhang Ning , Ren Yan , Chen Feng 
Published: January 2023

SummaryGrain length is one of the most important factors in determining wheat yield. Here, a stable QTL for grain length was mapped on chromosome 1B in a F10 recombinant inbred lines (RIL) population, and the gene TaGL1‐B1 encoding carotenoid isomerase was identified in a secondary large population through multiple strategies. The genome‐wide association study (GWAS) in 243 wheat accessions revealed that the marker for TaGL1‐B1 was the most significant among all chromosomes. EMS mutants of TaGL1 possessed significantly reduced grain length, whereas TaGL1‐B1‐overexpressed lines possessed significantly increased grain length. Moreover, TaGL1‐B1 strongly interacted with TaPAP6. TaPAP6‐overexpressed lines had significantly increased grain length. Transcriptome analysis suggested that TaPAP6 was possibly involved in the accumulation of JA (jasmonic acid). Consistently, JA content was significantly increased in the TaGL1‐B1 and TaPAP6 overexpression lines. Additionally, the role of TaGL1‐B1 in regulating carotenoids was verified through QTL mapping, GWAS, EMS mutants and overexpression lines. Notably, overexpression of TaGL1‐B1 significantly increased wheat yield in multiple locations. Taken together, overexpression of TaGL1‐B1 enhanced grain length, probably through interaction with TaPAP6 to cause the accumulation of JA that improved carotenoid content and photosynthesis, thereby resulted in increased wheat yield. This study provided valuable genes controlling grain length to improve yield and a potential insight into the molecular mechanism of modulating JA‐mediated grain size in wheat.
Quantitative analysis of wing interference patterns in Drosophila spp. using hyperspectral images
Authors: Takahashi Kazuo H. 
Published: January 2023

AbstractRecent studies have reported wing interference patterns (WIPs), which reflect the microstructure of the wing, for small insects belonging to the Diptera and Hymenoptera orders. WIPs have been evaluated using RGB or multispectral images, but in contrast to these approaches, hyperspectral images allow a more detailed analysis of spectral variation, which may not be captured by RGB or multispectral images. Here, I investigated the WIPs of 12 Drosophila species using hyperspectral images. The average spectrum was calculated for each of the six compartments of the wing region and for the entire wing, including all six compartments. This information was used to evaluate sexual and interspecific differences in the WIPs of 12 Drosophila species. In addition, the possibility of species discrimination based on WIPs was explored using the random forest machine learning algorithm. The present study demonstrates significant sex and interspecific differences in WIPs for each of the six compartments of the wing regions as well as for the entire wing region. The results of the random forest machine learning algorithm suggested the possibility of species identification based on WIPs.
Dendrobium nobile Lindl Polysaccharides Attenuate UVB‐induced Photodamage by Regulating Oxidative Stress, Inflammation and MMPs Expression in Mice Model
Authors: Long Yunluan , Wang Wuji , Zhang Yanyan , Zhang Shiqian , Li Zheng , Deng Jiang , Li Jingjie 
Published: January 2023

AbstractAcute ultraviolet B (UVB) irradiation predominantly leads to various skin disorders caused by photodamage. The major causes of UVB‐induced photodamage include oxidative stress, inflammatory infiltration and collagen degradation. The aim of the study was to elucidate whether DNP had protective effect on the skin of KM mice when exposed to UVB irradiation. The DNP protective properties to skin appearance and histopathological alterations in KM mice were evaluated by hematoxylin–eosin staining, toluidine blue staining, Gomori staining and Masson's trichrome staining and mast cell staining. In this study, DNP pretreatment promoted the activities of antioxidant enzymes, including superoxide dismutase, catalase and glutathione peroxidase, while decreased malondialdehyde level in UVB‐irradiated skin, along with downregulation of proteins expression of matrix metalloproteinases and reduction in the level of the proinflammatory cytokines. Based on these findings, we demonstrated that DNP displayed strong ameliorative effects on UVB‐induced acute photodamage for the first time, indicating that it would be a promoting ingredient candidate that could be used in antiphotodamage.
Autophagy regulation of virus infection in aquatic animals
Authors: Li Chen , Zhang Yunli , Zhao Xianliang , Li Li , Kong Xianghui 
Published: January 2023

AbstractAutophagy is a conserved intracellular degradation process that is required to maintain host homeostasis and cope with invading pathogens. Over the past few decades, studies on mammals have greatly increased our understanding of the relationship between autophagy and virus infection. Autophagy may convey the invader to lysosomes to degrade or activate the host immune response against virus replication. However, many viruses have developed some strategies that evade the degradative nature of autophagy or hijack this pathway for their gain. It follows that autophagy during viral infection is a double‐edged sword. In contrast to mammals, the review on autophagy modulated by the aquatic animal virus is limited. Here, after a brief description of the main information about autophagy, we highlight current progress on the interplays between autophagy and virus infection in aquatic animals, including the phenomenon of autophagy upon virus infection, the effect of modulating autophagy on virus replication, and the crosstalk between autophagy and immune response during virus infection. This review will help us better understand the pathogenic mechanism of aquatic animal viruses and develop proper antiviral countermeasures aimed at modulating autophagy.
Gathering the Nation in the Village: Intellectuals and the Cultural Politics of Nationality in the Late Soviet Period
Authors: Hutchinson Erin 
Published: January 2023

AbstractThis article analyzes the activities of three Soviet intellectuals–the Ukrainian artist Ivan Honchar, the Russian writer Vladimir Soloukhin, and the Gagauz poet Dmitri Kara Çoban–who launched independent projects to collect and preserve artifacts of pre‐Soviet peasant culture in the 1960s. Reacting against representations of their national culture in state museums that they considered inauthentic and incomplete, these three collectors were part of a broader movement of intellectuals in the post‐Stalin period who sought to return to the village as the original source of “authentic” national culture. State responses to these intellectual initiatives were determined not by clearly articulated policies made in Moscow, but through the “cultural politics of nationality”–the interaction of intellectuals, republican leaders and central authorities. Demonstrating the enduring impact of these three independent collecting projects on Soviet and post‐Soviet thought about the nation, this article argues that changing conceptions of the nation in the post‐Stalin period are best understood as the result of a nationalities process involving intellectuals, republican leaders and central authorities, rather than an explicitly defined nationalities policy.
Future‐Oriented Group Training for suicidal individuals: A randomized controlled trial
Authors: De Jaegere Eva , Stas Pauline , van Heeringen Kees , Dumon Eva , van Landschoot Renate , Portzky Gwendolyn 
Published: January 2023

AbstractIntroductionSuicide is a serious public health concern worldwide. Current psychological interventions targeting suicidal ideation and behavior are, however, limited and often lack convincing empirical support. Future‐Oriented Group Training (FOGT) targets crucial aspects of the suicidal process, thus possibly offering a promising intervention for suicidal ideation. This study aimed at investigating the short‐term and long‐term effects of FOGT on suicidal thoughts and related variables.MethodsA randomized controlled trial was conducted, comparing the intervention group (FOGT + treatment as usual (TAU)) to a control group (TAU) at pre and posttreatment and at a 12‐week follow‐up. Suicidal ideation was the primary outcome, while depressive symptoms, hopelessness, defeat, entrapment, worrying, and the ability for future‐oriented thinking were secondary outcomes.ResultsWhen compared to the control group, the intervention group showed significant decreases in worrying at posttreatment and significant increases in future‐oriented thinking at follow‐up. Pre‐post analyses within the intervention group showed significant small‐to‐medium effects for primary as well as most secondary outcomes. Changes in suicidal ideation, depression, hopelessness, and future‐oriented thinking remained significant at follow‐up.ConclusionThis study provides promising empirical evidence for the use of FOGT for individuals with suicidal ideation.
The dose–response of pain throughout a Nordic hamstring exercise intervention
Authors: Behan Fearghal P. , Opar David A. , Vermeulen Robin , Timmins Ryan G. , Whiteley Rodney 
Published: January 2023

The Nordic hamstring exercise (NHE) reduces hamstring injury incidence. Compliance to large exercise volumes of the NHE is poor, with exercise related soreness often seen as a contributing factor. We investigated the dose–response of NHE exposure with delayed onset muscle soreness (DOMS) and non‐DOMS pain. Forty males were randomized to a 6‐week intervention of four different NHE dosages: Group 1: very low volume; Group 2: low volume; Group 3: initial high to low volume; Group 4: low to high volume. Group 4 experienced more DOMS (p < 0.05) and non‐DOMS pain (p = 0.030) than other groups. High volumes of NHE increase DOMS and non‐DOMS pain while lower volume protocols have lesser DOMS and non‐DOMS pain responses.
Reflect In and Speak Out: An Autoethnographic Study on Race and the Embedded Sport Psychology Practitioner
Authors: Gupta Sahen 
Published: January 2023

This paper aims to present a critical experience of race for the embedded sport psychology practitioner from a non-WEIRD, migratory, Black, Asian, and minority ethnic doctoral student and trainee sport psychologist in the United Kingdom. In particular, I move from intrapersonal reflection to an interpersonal cultural analysis that (re)considers some assumptions in existing training and applied sport psychology practice. In the consequential ripples to these reflections, I evaluate and argue to modify (a) ideology of the culturally isolated practitioner, (b) self-recognition of unconscious bias and discrimination, and (c) routes to incorporate antidiscriminatory practice training in sport psychology education pathways. Using a rigorous autoethnographic approach on this novel area reveals several implications for applied practice and the development of professional philosophy. Using conversation vignettes, personal lived experience accounts on the impact of race on education and development as a practitioner are discussed in this original work. The goal is to make the invisible visible by exploring vulnerabilities in practice, client engagement, and educational training in an equal and nondiscriminatory manner.
Drone-assisted collection of environmental DNA from tree branches for biodiversity monitoring
Authors: Aucone Emanuele , Kirchgeorg Steffen , Valentini Alice , Pellissier Loïc , Deiner Kristy , Mintchev Stefano 
Published: January 2023

The protection and restoration of the biosphere is crucial for human resilience and well-being, but the scarcity of data on the status and distribution of biodiversity puts these efforts at risk. DNA released into the environment by organisms, i.e., environmental DNA (eDNA), can be used to monitor biodiversity in a scalable manner if equipped with the appropriate tool. However, the collection of eDNA in terrestrial environments remains a challenge because of the many potential surfaces and sources that need to be surveyed and their limited accessibility. Here, we propose to survey biodiversity by sampling eDNA on the outer branches of tree canopies with an aerial robot. The drone combines a force-sensing cage with a haptic-based control strategy to establish and maintain contact with the upper surface of the branches. Surface eDNA is then collected using an adhesive surface integrated in the cage of the drone. We show that the drone can autonomously land on a variety of branches with stiffnesses between 1 and 10
3
newton/meter without prior knowledge of their structural stiffness and with robustness to linear and angular misalignments. Validation in the natural environment demonstrates that our method is successful in detecting animal species, including arthropods and vertebrates. Combining robotics with eDNA sampling from a variety of unreachable aboveground substrates can offer a solution for broad-scale monitoring of biodiversity.
Supplemental Material: Carbon released by sill intrusion into young sediments measured through scientific drilling
Authors: Lizarralde Daniel , al. et 
Published: January 2023

<p>List of International Ocean Discovery Program (IODP) Expedition 385 co-author scientists; pore-water sulfate and methane profiles for Sites U1545 and U1546; and details of the site-to-site stratigraphic correlation. </p>
Supplemental Material: Carbon isotope and biostratigraphic evidence for an expanded Paleocene–Eocene Thermal Maximum sedimentary record in the deep Gulf of Mexico
Authors: Vimpere Lucas , al. et 
Published: January 2023

<p>Material and methods used in this study, details of the Rock-Eval, granulometric, carbon isotope, and calcareous nannofossil analyses, and correlation of the carbon isotopic curve with other sections worldwide. </p>
Interactome of Paraoxonase PON2 Reveals New Pathways for Tumor Growth Regulation
Authors: Karlov V. D. , Pestov N. B. , Shakhparonov M. I. , Korneenko T. V. 
Published: January 2023

Abstract
The interactome of paraoxonase-2 encoded by the PON2 gene was investigated. A cDNA library was screened using a yeast two-hybrid system to search for new proteins interacting with human PON2. Analysis of the identified candidates, along with previously published data on interactors obtained by other methods, indicates the presence of a significant number of indirect interactions between PON2 and EGFR and, consequently, possible regulation of tumor growth with mutant EGFR involving PON2.
Nephrocolocutaneous fistula from a staghorn calculus
Authors: Jacinto Cesar Karunungan , Lim Michael Geoffrey Lee , Lopez Marc Paul Jose , Serrano Dennis Pestano 
Published: January 2023

Fistula formation between the kidney, colon and the skin is an extremely rare complication arising from renal infections secondary to renal stone formation. During the 1980s, reports of nephrocolic fistulas, with or without involvement of the skin, were commonly caused by genitourinary tuberculosis. Due to improvements in diagnosis and specifically the development of anti-Koch’s therapy, the incidence of nephrocolic or nephrocolocutaneous fistulas has become uncommon especially in developed countries.We report a case of a patient residing in a developing country, presenting with a 20-year history of a left flank lesion extruding minimal purulent output daily. He was seen at the emergency department due to weakness and was managed as a case of urosepsis. Contrast-enhanced CT scan and fistulogram showed a staghorn calculus in the left kidney with connections to the descending colon and skin. The patient eventually underwent a left hemicolectomy with en bloc excision of the kidney and fistula tract.
Congenital glaucoma as a presenting feature of Rubinstein-Taybi syndrome in an infant with a novel pathogenic variant in theCREBBPgene
Authors: Snehi Sagarika , Kaur Anupriya , Chaudhry Chakshu , Kaushik Sushmita 
Published: January 2023

Rubinstein-Taybi syndrome, also known as broad thumb-hallux syndrome, is a rare autosomal dominant genetic disorder. This multiorgan syndrome is linked to a pathogenic mutation in theCREBBPorEBP300genes.We present a patient with a hitherto unreported constellation of anterior segment abnormalities, including congenital glaucoma, congenital corneal keloid, cataract, and distinct facial and systemic features including a high-arched palate, low-set posteriorly rotated ears, Café-au-lait spots on the back, broad terminal phalanges of hands and feet, and bilateral cryptorchidism. The characteristic dysgenetic angle features and ultrasound biomicroscopic findings described in this case report show the occurrence of concomitant congenital keloid with glaucoma.Genetic testing revealed a heterozygous one-base pair duplication in exon 3 of theCREBBPgene (c.886dupC), a novel frameshift pathogenic mutation in theCREBBPgene that has not been previously reported in a clinical setting.
The effect of health insurance and socioeconomic status on women’s choice in birth attendant and place of delivery across regions in Indonesia: a multinomial logit analysis
Authors: Lee John Tayu , McPake Barbara , Putri Likke Prawidya , Anindya Kanya , Puspandari Diah Ayu , Marthias Tiara 
Published: January 2023

BackgroundEvidence suggests that women gave birth in diverse types of health facilities and were assisted by various types of health providers. This study examines how these choices are influenced by the Indonesia national health insurance programme (Jaminan Kesehatan Nasional (JKN)), which aimed to provide equitable access to health services, including maternal health.MethodsUsing multinomial logit regression models, we examined patterns and determinants of women’s choice for childbirth, focusing on health insurance coverage, geographical location and socioeconomic disparities. We used the 2018 nationally representative household survey dataset consisting of 41 460 women (15–49 years) with a recent live birth.ResultsJKN coverage was associated with increased use of higher-level health providers and facilities and reduced the likelihood of deliveries at primary health facilities and attendance by midwives/nurses. Women with JKN coverage were 13.1% and 17.0% (p<0.05) more likely to be attended by OBGYN/general practitioner (GP) and to deliver at hospitals, respectively, compared with uninsured women. We found notable synergistic effects of insurance status, place of residence and economic status on women’s choice of type of birth attendant and place of delivery. Insured women living in Java–Bali and in the richest wealth quintile were 6.4 times more likely to be attended by OBGYN/GP and 4.2 times more likely to deliver at a hospital compared with those without health insurance, living in Eastern Indonesia, and in the poorest income quantile.ConclusionThere are large variations in the choice of birth attendant and place of delivery by population groups in Indonesia. Evaluation of health systems reform initiatives, including the JKN programme and the primary healthcare strengthening, is essential to determine their impact on disparities in maternal health services.
Linkages between malaria and malnutrition in co-endemic regions of India
Authors: Yadav Chander Prakash , Hussain Syed Shah Areeb , Pasi Shweta , Sharma Shweta , Bharti Praveen K , Rahi Manju , Sharma Amit 
Published: January 2023

IntroductionMalaria and malnutrition are key public health challenges in India. However, the relationship between them is poorly understood. Here, we aimed to elucidate the potential interactions between the two health conditions by identifying the areas of their spatial overlap.MethodsWe have analysed the district-wise undernutrition and malaria data of 638 districts of India across 28 states and 8 union territories. Data on malnutrition parameters viz. stunting, wasting, underweight and anaemia, sourced from the fourth National Family Health Survey (2015–2016), and malaria Annual Parasite Index (API) data of the same year (i.e, 2015), sourced from National Center of Vector Borne Diseases Control were analysed using local Moran’s I Index and logistic regression.ResultsAmong all the malnutrition parameters, we found underweight in children and anaemia in men to co-occur with malaria in the districts of Chhattisgarh, Jharkhand, Madhya Pradesh and Odisha. Further, districts with more than 36% underweight children (OR (95% CI): 2.31 (1.53 to 3.48)) and/or more than 23.6% male population with anaemia (OR (95% CI): 2.06 (1.37 to 3.11)) had higher odds of being malaria endemic districts (ie, Annual Parasite Index >1).ConclusionMalaria and malnutrition co-occur in the malaria-endemic parts of India. The high prevalence of undernutrition in children and anaemia among men may contribute to malaria endemicity in a particular region. Therefore, future research should be prioritised to generate data on the individual level. Further, malaria control interventions could be tailored to integrate nutrition programmes to disrupt indigenous malaria transmission in endemic districts.
Door-in-door-out times for patients with large vessel occlusion ischaemic stroke being transferred for endovascular thrombectomy: a Victorian state-wide study
Authors: Wong Joseph Zhi Wen , Dewey Helen M , Campbell Bruce C V , Mitchell Peter J , Parsons Mark , Phan Thanh , Chandra Ronil V , Ma Henry , Warwick Alexandra , Brooks Mark , Thijs Vincent , Low Essie , Wijeratne Tissa , Jones Sharon , Clissold Ben , Ngun Mei Yan , Crompton Douglas , Sriamareswaran Rumes Kanna , Rupasinghe Jayantha , Smith Karen , Bladin Chris , Choi Philip M C 
Published: January 2023

BackgroundTime to reperfusion is an important predictor of outcome in ischaemic stroke from large vessel occlusion (LVO). For patients requiring endovascular thrombectomy (EVT), the transfer times from peripheral hospitals in metropolitan and regional Victoria, Australia to comprehensive stroke centres (CSCs) have not been studied.AimsTo determine transfer and journey times for patients with LVO stroke being transferred for consideration of EVT.MethodsAll patients transferred for consideration of EVT to three Victorian CSCs from January 2017 to December 2018 were included. Travel times were obtained from records matched to Ambulance Victoria and the referring centre via Victorian Stroke Telemedicine or hospital medical records. Metrics of interest included door-in-door-out time (DIDO), inbound journey time and outbound journey time.ResultsData for 455 transferred patients were obtained, of which 395 (86.8%) underwent EVT. The median DIDO was 107 min (IQR 84–145) for metropolitan sites and 132 min (IQR 108–167) for regional sites. At metropolitan referring hospitals, faster DIDO was associated with use of the same ambulance crew to transport between hospitals (75 (63–90) vs 124 (99–156) min, p<0.001) and the administration of thrombolysis prior to transfer (101 (79–133) vs 115 (91–155) min, p<0.001). At regional centres, DIDO was consistently longer when patients were transported by air (160 (127–195) vs 116 (100–144) min, p<0.001). The overall door-to-door time by air was shorter than by road for sites located more than 250 km away from the CSC.ConclusionTransfer times differ significantly for regional and metropolitan patients. A state-wide database to prospectively collect data on all interhospital transfers for EVT would be helpful for future study of optimal transport mode at regional sites and benchmarking of DIDO across the state.