bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of prognostic nomograms for adult patients with papillary renal cell carcinoma (PRCC): A Retrospective Study
Authors: Guo Qingxiang , Li Shuaishuai , Zhu Jiawei , Wang Zewei , Jiang Lei , Li Zhen , Wang Junqi , Wen Rumin , Li Hailong 
Published: February 2023

Abstract
Objective
Creating two consensus nomograms for predicting overall survival (OS) and cancer-specific survival (CSS) in adult patients with papillary renal cell carcinoma was the aim of this study (pRCC).
Method
Using the Surveillance, Epidemiology, and End Results (SEER) database, a retrospective analysis of 1074 adult patients with pRCC from 2004 to 2015 was performed. These patients were then randomly divided into two independent cohorts with a ratio of 7:3 (training cohort: 752, validation cohort: 322). In a retrospective analysis of 752 patients from the training cohort, independent prognostic variables affecting OS and CSS were found. R software was used to create prognostic nomograms based on the findings of Cox regression analysis. The performance of the nomograms was assessed using the C-index, AUC curves, calibration curves, and DCA curves. Data from the 107 postoperative pRCC patients at the Affiliated Hospital of Xuzhou Medical University were used to externally validate the nomogram.
Results
For OS and CSS, the C-indices and AUCs of the training cohort and the validation cohort indicated that the model had excellent discrimination. The DCA curves demonstrate that the model is clinically applicable. The calibration curves in internal and external validation showed that the model's accuracy was high.
Conclusion
In the current study, we developed and validated a prognostic nomogram that accurately predicts the 3-, 5-, and 8-year OS and CSS of adult patients with pRCC. Clinicians can use this knowledge to direct the clinical management and counseling of patients with pRCC.
As(III)-oxidizing bacteria alleviate arsenite toxicity via reducing As accumulation, elevating antioxidative activities and modulating ionome in rice (Oryza sativa L.)
Authors: Lin Guobing , He Xiaoman , Zeng Jiayuan , Tang Jie , Wang Lin 
Published: February 2023

Abstract
Compared to other crops, paddy rice trends to accumulate more arsenic (As) from soils. The toxicity and mobility of As mainly depended on its chemical species. To mitigate As(III) stress to rice plants, As(III)-oxidizing strain SMS11 isolated from As-contaminated soils was employed in the current study. The rice seedlings were hydroponically cultivated in three groups: Control Group (without any addition), As(III) group (amended with 1 mg∙L-1 As(III)) and As(III)+B group (treated with As(III) and As(III)-oxidizing bacteria). Compared to Control group, the growth of rice shoots from As(III) group was significantly restricted. Inoculation with the bacteria could not only enhance the growth of the rice plants, but also significantly reduce the As level in the rice shoots. Evaluation of oxidative stress indices showed that superoxide dismutase activity in the rice plants was enhanced under As(III) stress, resulting in promoted inhibition ability of superoxide anion radical (O2•−). The activity of catalase in the rice shoots was weakened when exposed to As(III), increasing the risk of hydroxyl radical (•OH) formation. When co-cultivated with the bacteria, •OH formation was significantly inhibited in the rice shoots. Uptake of As elevated most nutrient element contents in the rice shoots simultaneously. The levels of most nutrient elements in the rice shoots were declined with alleviation of As stress after inoculation with the bacteria. The ionomics of the rice plants revealed significant variations with tissues and environmental conditions. The results represented ionomic profile as a promising tool to identify rice plants under different external conditions.
The Experiences of Online Students with Permanent Acquired Memory Related Issues: A qualitative study
Authors: Moore Justine E , Garip Gulcan 
Published: February 2023

Abstract

Higher education institutions within the United Kingdom have been making efforts to reduce the educational disparity that occurs between abled students and those with learning disabilities. Students with learning disabilities are more likely to abandon their studies than their able counterparts. However, given the unprecedented shift to online learning during the Covid − 19 pandemic, it is likely that those with learning disabilities have faced new challenges. Within psychology research into online learning, one population that has received little attention is students with permanent acquired memory-related issues. Therefore, this qualitative interpretative phenomenological analysis study explores the student experience of six mature university students who started online learning before Covid-19 to understand (i) what online learning means for students with permanent acquired memory related issues and (ii) what barriers and facilitators they encountered within their academic journey. Three themes were developed (i) Negotiating the challenges of online learning (ii) Online learning and the emotional experience, and (iii) Avoiding the gaps presented by online learning. The findings suggest that students’ online experience with permanent acquired memory loss was complex. Academic staff’s misunderstanding and the impact of Covid-19 combined to create several challenges, but support and individualised strategies aided course adherence.
Health expectancy in Russia in 1998-2022
Authors: Ramonov Alexander 
Published: February 2023

Abstract
Background:
The aim of this research is to estimate the scenarios of health expectancy dynamics following life expectancy dynamics
Methods:
Life tables including the information on health self-assessment.
Results:
From 2004 to 2019 the value of e(20)-h(20) for males increased from 4.5 years to 5.5 years (%e(20) remained constant on the level of 11%).
For females e(20)-h(20) decreased from 10.8 to 7.5 years (%e(20) decreased by 7% - from 20% to 13%).
Conclusion:
The positive dynamics of general health among females in Russia may be associated with a decrease in mortality from cardiovascular diseases among the elderly, which, combined with the positive dynamics of self-protective behavior, could show signs of the “cardiovascular revolution”.
Additional explanatory mechanism for this hypothesis is proposed.
Employability of Young Graduates in Togo
Authors: AMENOUDJI Ahoéfa Améyo , Wonyra Kwami Ossadzifo 
Published: February 2023

Abstract
This paper examines the factors influencing the employability of young graduates in Togo. The results obtained from econometric estimations using a binary Logit model reveal that the age range of 25–35 years and the married status positively affect the employability of young graduates of both sexes. In addition, being the head of the household is more motivating to seek work. On the other hand, the results suggest that women are less likely to get a job than their male counterparts. In addition, a high level of education decreases the chances of getting a job. Conversely, apart from Lomé, other urban centres negatively affect the employability of young graduates. Additional results also show that youth with disabilities have a low probability of finding employment. Multinomial logit estimates reveal that youth aged 25–35 in Togo choose the primary sector less than other sectors. Young women are more likely to be employed in the secondary sector.
Trends of Tropical Cyclone Parameters
Authors: Swedan Nabil 
Published: February 2023

Abstract
Tropical cyclones are seasonal phenomena that have to be calculated annually. The annual sea temperature rise in the tropics is small, of the order of 0.0018°C or less, and detecting mathematically significant trends of tropical cyclone parameters using Carnot cycle representation does not appear to be practically possible. The size of tropical cyclones is massive, and minute calculation errors spread large enough to overshadow the trends of the parameters. However, most of tropical cyclone structure may be determined by equations of classical mechanics, which are well defined and exact. This may reduce the calculation errors and mathematically significant and valid trends of tropical cyclone parameters determined. Accordingly, for equal temperature difference between sea water and air, the ocean heat flux required for tropical cyclone genesis decreases with latitude. Because sea temperature rise increases with latitude, tropical cyclones have been shifting their nascent locations farther away from the equator. Therefore, for the same annual energy available to tropical cyclones, the number of tropical cyclones increases with time. The increase is nearly equal to 4.08% ±0.76% per decade. Tropical cyclone intensity does not appear to be impacted by surface warming. The methodology provided may be used to assess trends of virtually all tropical cyclone parameters.
Clinic-Integrated Smartphone App (JomPrEP) to Improve Uptake of HIV Testing and Pre-exposure Prophylaxis Among Men Who Have Sex With Men in Malaysia: Mixed Methods Evaluation of Usability and Acceptability
Authors: Shrestha Roman , Altice Frederick L , Khati Antoine , Azwa Iskandar , Gautam Kamal , Gupta Sana , Sullivan Patrick Sean , Ni Zhao , Kamarulzaman Adeeba , Phiphatkunarnon Panyaphon , Wickersham Jeffrey A 
Published: February 2023

Background
HIV disproportionately affects men who have sex with men (MSM). In Malaysia, where stigma and discrimination toward MSM are high, including in health care settings, mobile health (mHealth) platforms have the potential to open new frontiers in HIV prevention.

Objective
We developed an innovative, clinic-integrated smartphone app called JomPrEP, which provides a virtual platform for Malaysian MSM to engage in HIV prevention services. In collaboration with the local clinics in Malaysia, JomPrEP offers a range of HIV prevention (ie, HIV testing and pre-exposure prophylaxis [PrEP]) and other support services (eg, referral to mental health support) without having to interface face to face with clinicians. This study evaluated the usability and acceptability of JomPrEP to deliver HIV prevention services for MSM in Malaysia.

Methods
In total, 50 PrEP-naive MSM without HIV in Greater Kuala Lumpur, Malaysia, were recruited between March and April 2022. Participants used JomPrEP for a month and completed a postuse survey. The usability of the app and its features were assessed using self-report and objective measures (eg, app analytics, clinic dashboard). Acceptability was evaluated using the System Usability Scale (SUS).

Results
The participants’ mean age was 27.9 (SD 5.3) years. Participants used JomPrEP for an average of 8 (SD 5.0) times during 30 days of testing, with each session lasting an average of 28 (SD 38.9) minutes. Of the 50 participants, 42 (84%) ordered an HIV self-testing (HIVST) kit using the app, of whom 18 (42%) ordered an HIVST more than once. Almost all participants (46/50, 92%) initiated PrEP using the app (same-day PrEP initiation: 30/46, 65%); of these, 16/46 (35%) participants chose PrEP e-consultation via the app (vs in-person consultation). Regarding PrEP dispensing, 18/46 (39%) participants chose to receive their PrEP via mail delivery (vs pharmacy pickup). The app was rated as having high acceptability with a mean score of 73.8 (SD 10.1) on the SUS.

Conclusions
JomPrEP was found to be a highly feasible and acceptable tool for MSM in Malaysia to access HIV prevention services quickly and conveniently. A broader, randomized controlled trial is warranted to evaluate its efficacy on HIV prevention outcomes among MSM in Malaysia.

Trial Registration
ClinicalTrials.gov NCT05052411; https://clinicaltrials.gov/ct2/show/NCT05052411

International Registered Report Identifier (IRRID)
RR2-10.2196/43318
Shear resistance of self-stressed elements without transverse reinforcement and with longitudinal bars made of polymer composites. Theoretical background
Authors: Tur Viktar V. , Varabei Aliaksandr P. 
Published: February 2023

Introduction. The problem of shear resistance of reinforced concrete elements without transverse reinforcement remains, as before, one of the most controversial in the theory of concrete structures. The interest in the problem arose anew due to the use of polymer composite (FRP) bars as longitudinal reinforcement in concrete structures. Models of shear resistance, included in the regulatory documents and formulated as suggestions in terms of elements reinforced with steel bars and FRP bars, are considered. It is shown that the critical shear crack theory (CSCT) can be adopted as a basis for formulating a model of shear resistance of FRP-reinforced elements. However, its provisions cannot be applied without appropriate adjustments, in particular, regarding the determination of the width of critical crack openings.
Materials and methods. To determine the shear strength of self-stressed concrete elements reinforced with FRP bars, a modified model was developed. As a result of an iterative procedure, this model makes it possible to determine an individual contribution of each of its main components to the total shear strength, taking into account the shape of a potential inclined crack, adopted in accordance with provisions of the Critical Shear Crack Theory (CSCT), as well as the width of the inclined crack opening at the level of longitudinal reinforcement, determined according to the bond-slip law for FRP bars.
Results. A modified mechanical shear resistance model of self-stressed concrete elements reinforced with polymer composite bars was developed. Its difference is that, in addition to the influence of initial self-stress, the bond law for longitudinal reinforcements made of FRP is taken into account (the modified bond-slip law) when cracking parameters are determined in the support zone. An iterative procedure is proposed for calculating the components and the total shear strength of elements made of concrete (including expansive concrete) without transverse reinforcement and with longitudinal reinforcement made of FRP bars.
Conclusions. The shear resistance model proposed for flexible self-stressed elements, reinforced with FRP bars, conveys the physical essence of the shear phenomenon and is applicable to various cases and loading patterns.
An experimental and theoretical approach to assessing the structure of fine-grained modified concretes
Authors: Dmitrieva Maria A. , Kogai Alina D. , Leitsin Vladimir N. , Tovpinets Aleksandr O. , Shinyaeva Maria V. 
Published: February 2023

Introduction. The development of approaches to assessing structural characteristics of multicomponent modified concretes using non-destructive testing methods at all stages of hydration is a relevant means focused on ensuring optimal rheological and strength characteristics of concretes.
Materials and methods. Modified fine-grained concrete was analyzed as the material under study, since its composition meets the requirements of additive technologies applied in the construction industry. Modification was implemented by introducing additives and mechanically activating the initial cement-sand composition. The strength of resulting specimens was controlled as of the onset of curing. Structure formation was studied using a computed tomography scanner.
Results. A tomography data processing approach was developed to evaluate the modified concrete’s structure. Key aspects of the stage-by-stage processing of specimens’ images were identified and a solution was obtained for determining the threshold values of correspondence between image shades having different density structures. In the course of compa­ring the results of the strength and structure study, the value of the percentage ratio of inclusions was obtained for various densities during the curing process.
Conclusions. The proposed data acquisition approach contributes to development of further research in this area; it can become a stage in developing a new concrete structure analysis method. The study of specimens at early curing stages in combination with non-destructive control methods contributes to (1) development of rapid assessment techniques, applied to the quality of materials, and (2) an efficiency increase in the process of development.
Antioxidant activity of ten grades of Indonesia black tea (Camellia sinensis (L.) O. Kuntze) liquor
Authors: Sudaryat Yayat , Kusmiyati Mimin , Pelangi Citra Ratu , Rustamsyah A , Rohdiana Dadan 
Published: February 2023

Tea is one kind of plant that is popular as a beverage. These plants contain antioxidant potential of flavonoids derived from polyphenol compounds. The research aimed to examine the antioxidant activity and to determine the con-tent of total phenols and total flavonoids from ten grades of Indonesian black tea liqour. Antioxidant activity was measured by the method of free radical scavenging by DPPH, total phenol content measured by Follin-Ciocalteu method, and total flavonoid content was measured by the method of AlCl3. The results of this research showed that The highest total phenol content contained in Dust III withÂ 225,80 mgGAE/100 g and the lowest content is BTL with 111,26 mgGAE/100 g. The test results showed that BBL has the highest total flavonoid content with 0,151 mg/g, while the lowest is BTL flavonoid with 0,086 mg/g. Meanwhile the highest antioxidant activity of ten grade of Indonesian black tea infusion obtained by Dust I, with IC50 97,00 Î¼g/ml. Meanwhile the lowest antioxidant activity with IC50 178,56 Î¼g/ml was obtained by BTL.
MENINGKATKAN KEMAMPUAN SISWA MENGGUNAKAN PENDEKATAN SETS PEMBELAJARAN BIOLOGI KELAS XI IPA 1 SMA NEGERI 9 PEKANBARU
Authors: Elza Jusnelvi 
Published: February 2023

Abstract: Improving Students' Ability to Use Biological Learning Sets Approach Class XI IPA 1 SMA Negeri 9 Pekanbaru. Based on observations made by researchers, it appears that the activeness and performance of students is not optimal, 65% of students do not respond to the material and questions from the teacher. With the SETS (Science, Environment, Technology, and Society) approach in learning biology it is hoped that students can master and apply it. From the results of observations in the first and second cycles obtained 55.6% of students completeness, while in the second cycle 100% completeness of students. Here an increase of 44.4% student completeness. The use of animation-based demonstration methods can be used in a concerted manner to obtain maximum results.Keywords: student ability, SETS, BiologyAbstrak: Meningkatkan Kemampuan Siswa Menggunakan Pendekatan Sets Pembelajaran Biologi Kelas XI IPA 1 SMA Negeri 9 Pekanbaru. Berdasarkan observasi yang dilakukan peneliti, tampak bahwa keaktifan dan kinerja peserta didik belum optimal, 65% peserta didik kurang memberi respon terhadap materi dan pertanyaan dari guru. Dengan pendekatan SETS (Science, Environment, Technology, and Society) dalam pembelajaran biologi diharapankan peserta didik dapat menguasai dan menerapkannya. Dari hasil observasi pada siklus I dan II diperoleh hasil 55,6 % ketuntasan siswa, sedangkan pada siklus II 100 % ketuntasan siswa. Disini terjadi peningkatan sebesar 44.4 % ketuntasan siswa. Penggunaan metode demontrasi berbasis animasi bisa digunakan secara berkesimabungan untuk memperoleh hasil yang maksimal.Kata Kunci: kemampuan siswa, SETS, Biologi
PERANCANGAN SISTEM INFORMASI ADMINISTRASI PADA QUALITY FRESH LAUNDRY PEKANBARU
Authors: Wijoyo Hadion 
Published: February 2023

Abstract: Design of Administrative Information Systems at Quality Fresh Laundry Pekanbaru. Php-based information system is a tool in a computerized system that has been equipped with features and designed in such a way as needed to input certain data that aims to simplify, speed up and make accurate data that has been processed. At this time the information system has become the main choice for giving and searching for information on a particular data. Laundry or laundry is a facility where clothes are washed and dried. Laundry usually uses an automatic washing machine called a laundromat or general trademark.Keywords: Computerized System, Administration, LaundryAbstrak: Perancangan Sistem Informasi Administrasi Pada Quality Fresh Laundry Pekanbaru. Sistem informasi berbasis php merupakan sebuah sarana didalam sistem komputerisasi yang telah dilengkapi dengan fitur- fitur dan didesain sedemikian rupa sesuai dengan kebutuhan yang akan digunakan pada penginputan suatu data tertentu yang bertujuan untuk mempermudah, mempercepat dan mengakuratkan data yang telah diolah. Pada saat ini sistem informasi telah menjadi pilihan utama untuk memberi dan mencari informasi pada sebuah data tertentu. Laundry atau Binatu adalah fasilitas di mana pakaian dicuci dan dikeringkan. Binatu biasa menggunakan mesin cuci otomatis yang disebut sebagai laundromat atau merk dagang umum. Kata kunci : Sistem Komputerisasi, Administras, Laundry
IMPLEMENTASI METODE JOB ORDER COSTING PADA SISTEM INFORMASI PRODUKSI BERBASIS WEB
Authors: Suendri Suendri , Triase Triase , Afzalena Siti 
Published: February 2023

Abstrack : Implementation Of Job Order Costing Methods In Web-Based Production Information Systems. This method is applied in the production information system for the calculation of gypsum production because using this method is more efficient because the calculation is done as a whole starting from raw materials, labor costs to factory overhead costs. in determining the price. In the process of expenditure and entry of goods as well as reports in production are not yet efficient and effective are still calculated manually and reports are still recorded so that calculations still occur errors and loss of production reports. The place of the research was carried out in the company CV Rifqy Gypsum.Keywords : System, Information, Production.Abstrak : Implementasi Metode Job Order Costing Pada Sistem Informasi Produksi Berbasis Web. Metode ini diterapkan dalam sistem informasi produksi untuk perhitungan produksi gypsum karena dengan menggunakan metode ini lebih efesien karena perhitungan dilakukan secara keseluruhan mulai dari bahan baku, biaya tenaga kerja hingga biaya overhead pabrik. Pada proses produksi gypsum menggunakan bahan baku yang sesuai takaran dan diperhitungkan sehingga memudahkan dalam menentukan harga. Pada proses pengeluaran dan pemasukan barang serta laporan dalam produksi belum efesien dan efektif masih diperhitungkan secara manual dan laporan masih dicatat sehingga perhitungan masih terjadi kesalahan dan hilangnya laporan produksi. Tempat pelaksanaan penelitian dilakukan di perusahaan CV Rifqy Gypsum.Kata Kunci : Sistem, Informasi, Produksi.