bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of suicidal behaviour among students living in Muslim-majority countries: systematic review and meta-analysis
Authors: Arafat S. M. Yasir , Baminiwatta Anuradha , Menon Vikas , Singh Rakesh , Varadharajan Natarajan , Guhathakurta Saptarshi , Mahesar Rameez Ali , Rezaeian Mohsen 
Published: April 2023

BackgroundAssessing suicidal behaviours among students would help to understand the burden and enhance suicide prevention.AimsWe aimed to determine the prevalence of suicidal behaviour among students living in Muslim-majority countries.MethodWe followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A systematic search was conducted in Medline, EMBASE and PsycINFO. Meta-analyses were performed to pool the lifetime, 1-year and point prevalence rates for suicidal ideation, plans and attempts.ResultsFrom 80 studies, 98 separate samples were included in this analysis. The majority (n= 49) were from the Eastern Mediterranean, and 61 samples were of university students. The pooled prevalence of suicidal ideation was 21.9% (95% CI 17.4%–27.1%) for lifetime, 13.4% (95% CI 11.1%–16.1%) for the past year and 6.4% (95% CI 4.5%–9%) for current. The pooled prevalence of suicide plans was 6.4% (95% CI 3.7%–11%) for lifetime, 10.7% (95% CI 9.1%–12.4%) for the past year and 4.1% (95% CI 2.7%–6.2%) for current. The pooled prevalence of suicide attempts was 6.6% (95% CI 5.4%–8%) for lifetime and 4.9% (95% CI 3.6%–6.5%) for the past year. The lifetime prevalence of suicidal ideation was highest (46.2%) in South-East Asia, but the 12-month prevalence was highest (16.8%) in the Eastern Mediterranean.ConclusionsThe study revealed notably high rates of suicidal behaviours among students living in Muslim-majority countries. However, the quality of studies, differences in regional and cultural factors, stages of studentship and methods of measurement should be considered when generalising the study results.
A Three-Step Taxane Titration Protocol Decreases Hypersensitivity Reactions During First and Second Exposures
Authors: Lynch Donna-Marie , Menon Susanne , Mazzola Emanuele , Costa Jennifer , Jabaley Terri 
Published: April 2023

INTRODUCTION: Patients receiving taxanes are at risk for developing hypersensitivity reactions (HSRs) primarily during first and second lifetime exposures. Immediate HSRs require emergency care and can interfere with the continuation of preferred treatment. Although different approaches to slow titration have been used successfully for desensitization after HSR occurrence, there are no standardized recommendations for taxane titration to prevent HSRs. PURPOSE: To determine if a gradual, three-step infusion rate titration decreases the rate and severity of immediate HSRs during first and second lifetime exposures to paclitaxel and docetaxel. METHODS: We used a prospective, interventional design with historical comparisons to evaluate a sample of 222 first and second lifetime exposure paclitaxel and docetaxel infusions. The intervention was a three-step infusion rate titration provided at the initiation of first and second lifetime exposures. Ninety-nine titrated infusions were compared with 123 historical records of nontitrated infusions. RESULTS: Compared with the nontitrated group (n = 123), the titrated group (n = 99) had significantly less HSRs (19% v 7%; P = .017). No significant difference in HSR severity was found between groups ( P = 1.00). However, four nontitrated patients received epinephrine, and one required transfer to the emergency department (ED) because of reaction severity. In contrast, no titrated patients received epinephrine or required transfer to the ED. In the nontitrated group, seven patients did not complete their infusions versus one patient in the titrated group. CONCLUSION: A standardized, three-step infusion rate titration prevented HSR occurrence. Significant issues affecting practice feasibility and sustainability were addressed.
Peripheral Intravenous Waveform Analysis Responsiveness to Subclinical Hemorrhage in a Rat Model
Authors: Barajas Matthew B. , Riess Matthias L. , Hampton Matthew J. W. , Li Zhu , Shi Yaping , Shotwell Matthew S. , Staudt Genevieve , Baudenbacher Franz J. , Lefevre Ryan J. , Eagle Susan S. 
Published: April 2023

BACKGROUND:
Early detection and quantification of perioperative hemorrhage remains challenging. Peripheral intravenous waveform analysis (PIVA) is a novel method that uses a standard intravenous catheter to detect interval hemorrhage. We hypothesize that subclinical blood loss of 2% of the estimated blood volume (EBV) in a rat model of hemorrhage is associated with significant changes in PIVA. Secondarily, we will compare PIVA association with volume loss to other static, invasive, and dynamic markers.

METHODS:
Eleven male Sprague Dawley rats were anesthetized and mechanically ventilated. A total of 20% of the EBV was removed over ten 5 minute-intervals. The peripheral intravenous pressure waveform was continuously transduced via a 22-G angiocatheter in the saphenous vein and analyzed using MATLAB. Mean arterial pressure (MAP) and central venous pressure (CVP) were continuously monitored. Cardiac output (CO), right ventricular diameter (RVd), and left ventricular end-diastolic area (LVEDA) were evaluated via transthoracic echocardiogram using the short axis left ventricular view. Dynamic markers such as pulse pressure variation (PPV) were calculated from the arterial waveform. The primary outcome was change in the first fundamental frequency (F1) of the venous waveform, which was assessed using analysis of variance (ANOVA). Mean F1 at each blood loss interval was compared to the mean at the subsequent interval. Additionally, the strength of the association between blood loss and F1 and each other marker was quantified using the marginal R
2 in a linear mixed-effects model.

RESULTS:
PIVA derived mean F1 decreased significantly after hemorrhage of only 2% of the EBV, from 0.17 to 0.11 mm Hg, P = .001, 95% confidence interval (CI) of difference in means 0.02 to 0.10, and decreased significantly from the prior hemorrhage interval at 4%, 6%, 8%, 10%, and 12%. Log F1 demonstrated a marginal R
2 value of 0.57 (95% CI 0.40–0.73), followed by PPV 0.41 (0.28–0.56) and CO 0.39 (0.26–0.58). MAP, LVEDA, and systolic pressure variation displayed R
2 values of 0.31, and the remaining predictors had R
2 values ≤0.2. The difference in log F1 R
2 was not significant when compared to PPV 0.16 (95% CI −0.07 to 0.38), CO 0.18 (−0.06 to 0.04), or MAP 0.25 (−0.01 to 0.49) but was significant for the remaining markers.

CONCLUSIONS:
The mean F1 amplitude of PIVA was significantly associated with subclinical blood loss and most strongly associated with blood volume among the markers considered. This study demonstrates feasibility of a minimally invasive, low-cost method for monitoring perioperative blood loss.
Ultramassive Transfusion for Trauma in the Age of Hemostatic Resuscitation: A Retrospective Single-Center Cohort From a Large US Level-1 Trauma Center, 2011–2021
Authors: Muldowney Maeve , Liu Zhinan , Stansbury Lynn G. , Vavilala Monica S. , Hess John R. 
Published: April 2023

BACKGROUND:
Uncontrolled bleeding is a leading cause of death in trauma. In the last 40 years, ultramassive transfusion (UMT; ≥20 units of red blood cells [RBCs]/24 hours) for trauma has been associated with 50% to 80% mortality; the question remains as to whether the increasing number of units transfused in urgent resuscitation is a marker of futility. We asked whether the frequency and outcomes of UMT have changed in the era of hemostatic resuscitation.

METHODS:
We performed a retrospective cohort study of all UMTs in the first 24 hours of care over an 11-year period at a major US level-1 adult and pediatric trauma center. UMT patients were identified, and a dataset was built by linking blood bank and trauma registry data, then reviewing individual electronic health records. Success in achieving hemostatic proportions of blood products was estimated as (units of plasma + apheresis-platelets-in-plasma + cryoprecipitate-pools + whole blood]/[all units given] ≥0.5. Demographics, injury type (blunt or penetrating), severity (Injury Severity Score [ISS]), severity pattern (Abbreviated Injury Scale score for head [AIS-Head] ≥4), admitting laboratory, transfusion, selected emergency department interventions, and discharge status were assessed using χ2 tests of categorical association, the Student t-test of means, and multivariable logistic regression. P <.05 was considered significant.

RESULTS:
Among 66,734 trauma admissions from April 6, 2011 to December 31, 2021, we identified 6288 (9.4%) who received any blood products in the first 24 hours, 159 of whom received UMT (0.23%; 154 aged 18–90 + 5 aged 9–17), 81% in hemostatic proportions. Overall mortality was 65% (n = 103); mean ISS = 40; median time to death, 6.1 hours. In univariate analyses, death was not associated with age, sex, or more RBC units transfused beyond 20 but was associated with blunt injury, increasing injury severity, severe head injury, and failure to receive hemostatic blood product ratios. Mortality was also associated with decreased pH and evidence of coagulopathy at admission, especially hypofibrinogenemia. Multivariable logistic regression showed severe head injury, admission hypofibrinogenemia and not receiving a hemostatic resuscitation proportion of blood products as independently associated with death.

CONCLUSIONS:
One in 420 acute trauma patients at our center received UMT, a historically low rate. A third of these patients lived, and UMT was not itself a marker of futility. Early identification of coagulopathy was possible, and failure to give blood components in hemostatic ratios was associated with excess mortality.
Comparison of Bifrontal Craniotomy and Multiple Burr Hole Encephalogaleoperiosteal-Synangiosis for Pediatric Moyamoya Disease: An Experience of 346 Patients
Authors: Kim Joo Whan , Phi Ji Hoon , Lee Ji Yeoun , Koh Eun Jung , Kim Kyung Hyun , Kim Hee-Soo , Kim Seung-Ki 
Published: April 2023

BACKGROUND AND OBJECTIVES:
Moyamoya disease (MMD) is a steno-occlusive disease treated with revascularization surgery. Craniotomy and multiple burr hole encephalogaleoperiosteal-synangiosis (EGPS) are used for revascularization of the anterior cerebral artery territory. The aim of this study was to compare the clinical outcome between the 2 surgical methods in pediatric patients with MMD.

METHODS:
A retrospective review of patients with MMD who underwent bifrontal indirect bypass surgery was performed. Clinical features, perioperative data, and angiographic, perfusion, and functional outcomes were compared between the 2 groups. Propensity score matching was performed to compare the perioperative characteristics and clinical outcomes.

RESULTS:
A total of 346 patients were included in this study, 111 patients underwent bifrontal craniotomy EGPS, and 235 patients had bifrontal multiple burr hole EGPS. An insignificant higher rate of postoperative infarction (11.7% vs 5.5%, P = .072) and more postoperative hemorrhage occurred in the craniotomy EGPS group (3.6% vs 0%, P = .004). Of the 83 patients selected with propensity score matching for each group, the duration of operation was shorter (P < .001) and the amount of intraoperative bleeding was significantly less in the multiple burr hole EGPS group (P = .008). There was no difference in clinical outcomes between the 2 groups.

CONCLUSION:
Bifrontal multiple burr hole EGPS has benefits over craniotomy with shorter surgical time, less intraoperative bleeding, fewer postoperative complications, and comparable perfusion and functional outcomes. Multiple burr hole EGPS is a safe and effective method that might be considered for revascularization of the anterior cerebral artery territory in pediatric patients with MMD.
Disease association and comparative genomics of compositional bias in human proteins
Authors: Kouros Christos E. , Makri Vasiliki , Ouzounis Christos A. , Chasapi Anastasia 
Published: April 2023

Background: The evolutionary rate of disordered protein regions varies greatly due to the lack of structural constraints. So far, few studies have investigated the presence/absence patterns of compositional bias, indicative of disorder, across phylogenies in conjunction with human disease. In this study, we report a genome-wide analysis of compositional bias association with disease in human proteins and their taxonomic distribution. Methods: The human genome protein set provided by the Ensembl database was annotated and analysed with respect to both disease associations and the detection of compositional bias. The Uniprot Reference Proteome dataset, containing 11297 proteomes was used as target dataset for the comparative genomics of a well-defined subset of the Human Genome, including 100 characteristic, compositionally biased proteins, some linked to disease. Results: Cross-evaluation of compositional bias and disease-association in the human genome reveals a significant bias towards biased regions in disease-associated genes, with charged, hydrophilic amino acids appearing as over-represented. The phylogenetic profiling of 17 disease-associated, proteins with compositional bias across 11297 proteomes captures characteristic taxonomic distribution patterns. Conclusions: This is the first time that a combined genome-wide analysis of compositional bias, disease-association and taxonomic distribution of human proteins is reported, covering structural, functional, and evolutionary properties. The reported framework can form the basis for large-scale, follow-up projects, encompassing the entire human genome and all known gene-disease associations.
P2P lending platforms in Malaysia: What do we know?
Authors: Nguyen Lan Thi Phuong , Kalabeke Wisdom , Muthaiyah Saravanan , Cheng Ming Yu , Hui Kwan Jing , Mohamed Hazik 
Published: April 2023

Background - With the recent evolution of Financial Technology (FinTech), 11 peers to peer (P2P) lending platforms have been regulated by the Securities Commission in Malaysia since 2016. P2P lending platforms offer new investment opportunities to individual investors to earn higher rates on return than what traditional lenders usually provide. However, individual investors may face higher potential risks of default from their borrowers. Therefore, individual investors need to understand the potential exposure to such P2P lending platforms to make an effective investment decision. This study aims to explore the potential risk exposures that individual investors may experience at Malaysia's licensed P2P lending platforms. Methods - Based on data collected manually from nine P2P lending platforms over five months, relationships between interest rates and various risk classifying factors such as credit rating, industry, business stage, loan purpose, and loan duration are examined. Results- This study shows that loans with a similar credit rating and with or without similar loan purpose; and a business stage may offer investors significantly different interest rates. In addition, loans with shorter durations may provide investors with higher interest rates than those with longer durations. Finally, loans issued by companies from the same industry appeared to be charged with similar interest. These findings are valuable to investors to prepare themselves before making their investments at the P2P lending platforms. Conclusion- With first hand-collected data, this study provides an original insight into Malaysia's current P2P lending platforms. Findings obtained for relationships between interest rates and risk classifying factors such as credit rating, industry, business stage, loan purpose and loan duration are valuable to investors of Malaysian P2P lending platforms.
Discovery of a rare stiped puffball Calostoma junghuhnii in Neora Valley National Park, India: A new record for West Bengal, India
Authors: MAJUMDAR SHUVADEEP , RAI BUDDHA SINGH , RAI AJIT , GHOSH UJJAL , BHATTACHARYYA SILANJAN , BOSE ANIMESH , GOSWAMI NISHA , CHAKRABORTY DYUTIPARNA , SARKAR JIT , MUKHERJEE SUDIPTA , ACHARYA KRISHNENDU , PRADHAN PRAKASH 
Published: April 2023

Abstract. Majumdar S, Rai BS, Rai A, Ghosh U, Bhattacharyya S, Bose A, Goswami N, Chakraborty D, Sarkar J, Mukherjee S, Acharya K, Pradhan P. 2022. Discovery of a rare stiped puffball Calostoma junghuhnii in Neora Valley National Park, India: A new record for West Bengal, India. Asian J For 6: 9-14. The varied topography, soil, and climate of West Bengal, India, make conducive conditions for nurturing the magnificent diversity of macrofungi and their habitats. During an exploration of macro-fungal diversity in Neora Valley National Park, West Bengal, India, in 2021, basidiocarps of Calostoma (Calostomataceae) were collected and photographed, along with macro-morphological and ecological notes were taken. The specimens were identified through macro and micro-morphological characters following standard literature. Amplified description of Calostoma junghuhnii (Schltdl. & Müll. Berol.) Massee, along with necessary figures and photographs, is presented in this paper. A literature survey revealed that C. junghuhnii is a new record for West Bengal. The outcome of the present study would enrich data related to the macro-fungal diversity in the state of West Bengal, India.
Taxonomy, distribution and statistical ecology of black mildews fungi reported from Maharashtra state of India
Authors: DUBEY RASHMI , MOONAMBETH NEELIMA , PANDEY AMIT DIWAKAR 
Published: April 2023

Abstract. Dubey R, Moonambeth N, Pandey AD. 2022. Taxonomy, distribution and statistical ecology of black mildew fungi reported from Maharashtra state of India. Asian J For 6: 97-125. The Maharashtra state of India represents some of the best non-equatorial tropical forests in the world. It supports many endemic species of plants, animals, and microorganisms, especially in the Western Ghats, India. Moreover, a research project entitled "Foliicolous fungi of Maharashtra" was allotted by the Botanical Survey of India, Ministry of Environment, Forests, and Climate change, India, to carry out the mycological studies. As part of this project, ongoing studies were carried out on black mildew fungi of this state. The present studies offer a taxonomic account, distribution, and ecological parameters of 72 black mildew taxa collected from different areas of Maharashtra state of India. The present study provides three new records of fungi to India, 31 new host records to India, 40 new records of fungi to the Maharashtra state of India, and one new variety, viz., Asterina jasmini Hansf. var. koyani var.nov., depicted by checklist and Figures. In addition, a comprehensive table containing information on location, date of collection, name of the collector, and new records are given for ready reference. During this study, Meliola was the dominant genus with 35 species, whereas Meliolina mollis was the dominant taxon obtained from a maximum of 5 collections. More than 90% of black mildew species are collected from the Western Ghats Districts. In diversity indices, Gini-Simpson's was 0.9818, and Shannon's was 4.1668. Pielou's evenness index was 0.9743, causing true diversity, calculated as an effective number of species (64), to be less than observed species richness (72).
Vegetation diversity, structure, composition and carbon stock of community managed forests of Mid-hills, Nepal
Authors: JOSHI PADAM , JOSHI RAJEEV , SAPKOTA RAMESH PRASAD , PANTA MANOJ , CHAND PRIYANKA 
Published: April 2023

Abstract. Joshi P, Joshi R, Sapkota RP, Panta M, Chand P. 2023. Vegetation diversity, structure, composition and carbon stock of community managed forests of Mid-hills Nepal. Asian J For 7: 29-36. Depending on management practices, forests can serve as both carbon sinks and sources. The goal of reducing carbon emissions and increasing the carbon sink is thought to be feasible if carbon reservoirs in current forests are protected and conserved. This study was objectively conducted to assess the vegetation diversity, structure, and carbon stock of the Mid-hills of Nepal. The study was undertaken in the Lanta Community Forest, Jajarkot District, Nepal, which has an extent of 38.65 hectares. Data for vegetation analysis and carbon stock assessment were collected using systematic random sampling using quadrats of 10×10 m with a total number of 35 quadrats. Within each quadrat, individual trees and bamboo were identified in the sites, and their height (m) and DBH (cm) were measured. Density, frequency, basal area, and Important Value Index (IVI) were calculated as structural parameters of vegetation. The Above-Ground Tree Biomass (AGTB) and Below-Ground Tree Biomass (BGTB) were calculated using an allometric equation based on tree diameter, height, and wood-specific gravity. The species diversity, species richness, and evenness were found to be 2.2, 2.35, and 0.83, respectively. A total of 14 tree species, with 723 individuals and one bamboo species were recorded. Rhododendron arboreum Sm. had the highest tree density with 211 trees/ha, while Tsuga dumosa (D.Don) Eichler had the highest IVI. Total wood volume, biomass, and total carbon stock were estimated at 15.37 m3 ha-1, 31.99 t ha-1, and 15.03 t ha-1, respectively. There was a strong negative correlation (r = -0.59) between R. arboreum and R. campanulatum D. Don and a strong positive correlation (r = +0.65) between Malus sikkimensis and Machilus species. For the preservation and sustainable management of community forests, information regarding the structure, composition, and dominance of tree species is provided by the study. The establishment of community forests is thus demonstrated in this article as a means of promoting the protection and preservation of regional biodiversity.