bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hysterectomy through Minimally Invasive Surgery for Cervical High-grade Intraepithelial Neoplasia: Reassessment of the Specimens’ Eligibility for Histological Examination
Authors: Kurihara Shuichi , Hamasaki Yoichiro , Onjo Sachiko , Nishiyama Kenichi , Nishida Makoto 
Published: August 2023

Objectives:
The objective was to investigate the microscopic artifacts made in the uterus of cervical high-grade squamous intraepithelial lesion (HSIL) resected by hysterectomy through minimally invasive (H-MI) procedures and to verify whether these specimens are suitable for histopathological assessment.

Materials and Methods:
This single-center retrospective study analyzed 28 patients with cervical HSIL, consisting of 21 premenopausal and seven postmenopausal women, who underwent H-MI. The proportion of the cervical mucosa covered by intact surface epithelium (residual ratio [RR]) was measured on microscopically. Surgical margin’s status was also verified.

Results:
All cases developed detachment of the cervical surface epithelium to a varying extent. The RR was significantly higher in the premenopausal patients (median: 75.5%) than in the postmenopausal patients (median: 37.6%). Among the premenopausal patients, the RR was lower in the cases on whom uterine manipulator (UM) was used (median: 70.5%) than in the cases without UM use (median 92.7%). Among the 21 cases whose resected uterus contained HSIL, the vaginal resection margin was not assessable in three (14.2%) of the seven postmenopausal cases due to the artifact.

Conclusion:
Although transvaginal manipulation of the uterus causes detachment of the cervical surface epithelium, H-MI for cervical HSIL provides an acceptable specimen for histological assessment in premenopausal patients, even if UM is used. In postmenopausal women, H-MI easily develops artifactual loss of cervical surface epithelium, sometimes providing an unfavorable specimen for microscopic assessment.
Dermatological Manifestations in COVID-Related Illness in Children: A Retrospective Observational Study at a Tertiary Care Hospital of Eastern India
Authors: Purkait Radheshyam , Roy Kakali , Manna Nivedita , Samanta Moumita , Mahapatra Tapan Kumar Sinha 
Published: August 2023

Objectives:
To identify the spectrum of cutaneous manifestations and to evaluate temporal relationship between each type of dermatological lesions and the severity of COVID-19-related illness in the pediatric population.

Subjects and Methods:
Retrospective observational study on 35 children (upto12 years) from Kolkata and different district areas of West Bengal, admitted to our tertiary care hospital with COVID-related illnesses (COVID-19 and/or multisystem inflammatory syndrome in children [MIS-C]).

Results:
Maculopapular rash was heading the list (n = 18, 51.4%) followed by chilblain-like lesions (n = 12, 34.2%), vasculistic lesion (n = 8, 22.8%), vesicular rash (n = 5, 14.3%), and urticaria (n = 3, 8.5%). In majority of patients (n = 26, 74.2%), dermatologic manifestations proceeded (n = 16, 45.7%) or merged (n = 10, 28.6%) with the onset of systemic symptoms. In rest of the patients (n = 9, 25.7%), skin manifestations occurred after the systemic symptoms, particularly in vascular lesions. 57.1% children required pediatric intensive care unit (PICU) admission. All children with vasculitis (n = 8) required PICU admission and 87.5% (n = 7) of them needed inotrope support. Intravenous immunoglobulin (IVIG) was mostly given in children with chilblains (n = 11, 92%). Methylprednisolone and repeat dose of IVIG was mostly needed in patients with vasculitis (75% and 25% of vasculitis children, respectively). The duration of PICU stay was least in patients with vesicular rash (4.4 ± 2.5 days) and longest in vasculistic lesions (18.75 ± 1 days), highest being 56 days. The overall mortality rate among MIS-C patients with cutaneous manifestations was 25.7% (n = 9) while patients with vasculistic lesions had the highest mortality rate of 50% (n = 4).

Conclusion:
Our study finding reveals that COVID-related disease severity is highly depends on the type of skin lesions but not just on mere occurrence of skin manifestations. Lesions such as maculopapular, chilblains, and vesicular rash had good prognosis and urticaria and vasculitis had poor prognosis.
Clinicoradiological parameters predicting operative difficulty in laparoscopic partial nephrectomy for renal tumors
Authors: Pirzada Faisal Masood , Sood Rajeev , Taneja Anil , Sharma Umesh , Goel Hemant Kumar , Gahlawat Sumit 
Published: August 2023

Introduction:
The number of renal tumors amenable to laparoscopic surgery is rising, both, due early detection by improved imaging techniques and due to progressive improvements in minimal access surgery. Conversion to open surgery, which is a significant event, can be minimized by proper case selection. We assessed the pre-operative factors that can predict the operative difficulty and can help in case selection, thus avoiding complications and reducing the chances of conversion to open.

Methods:
One hundred and sixteen patients (73 males and 43 females) with the mean age of 50.78 ± 14.2 years, meeting the inclusion criteria underwent transperitoneal laparoscopic partial nephrectomy (LPN). Various clinical, anthropometric, radiological, and pathological parameters were recorded. Intraoperative difficulty was assessed and graded on a scale of 1 (easiest) to 4 (most difficult or open conversion) by an independent observer to calculate the difficulty score, which along with the other parameters of operative difficulty, was used to calculate the difficulty scale. Significant parameters on the univariate analysis, were subjected to a multivariate analysis, to find parameters that can predict the operative difficulty.

Results:
The mean age was 52 ± 14.29 years, mean size was 4 ± 1.04 cm, male:female ratio was 1.6:1, most of the tumors were exophytic (60%) and anteriorly located (62%) and had a mean perinephric fat surface density (PnFSD) of 6446.026 ± 2244 surface density pixel units (SDPU). On the univariate analysis, age >60 years, Eastern Cooperative Oncology Group performance score >1, presence of perinephric fat stranding, increased PnFSD (>10,000 SDPU), large tumor size (>4 cm), hilar/posterior location, endophytic tumors and higher clinical stage were significantly associated with intraoperative difficulty. However, on the multivariate analysis, no single factor could independently predict intraoperative difficulty in LPN for Renal tumors.

Conclusion:
It is difficult to predict the intra-operative difficulty during LPN. Feasibility of LPN should be based on multiple factors rather than a single factor.
Intervertebral disc degeneration and vertebral end plate damage in acute lumbar disc herniation
Authors: Nehru Arul P , Kanna Rishi M , Shetty Ajoy P , Shanmuganathan Rajasekaran 
Published: August 2023

Abstract

Background:
Although microtrauma, gene polymorphisms, or subclinical infection could initiate lumbar disc herniation (LDH), the final pathway culminating in herniation can involve two possible trajectories—degeneration of nucleus pulposus or vertebral end plate (EP) damage. We performed a retrospective case–control study to understand the relative role played by disc degeneration (DD) and EP changes in acute LDH.

Materials and Methods:
MRI of 300 consecutive patients with acute LDH (<6 weeks) was evaluated for the type of LDH, severity of DD by Pfirrmann’s grading, and EP Modic changes (MC) for its type, distribution, and location in EPs. Among the1500 discs evaluated in 300 patients, 308 had disc herniation (cases) and 1192 acted as controls.

Results:
98.8% of LDH had grade ≥3 DD (P < 0.001). The mean DD was higher in herniated discs (P < 0.05). From a mean 1.98 in normal discs, it increased to 3.31 in disc bulges, 3.73 in disc protrusions/extrusions, and 3.83 in sequestrations. Herniated discs had more MCs than normal discs (38.3%, 118/308) (P < 0.001). Although in normal discs, only 7.7% had MC, herniated disc subtypes showed a progressive increase in the incidence of MC (26.2% in disc bulges, 37.5% in disc protrusion/extrusions, and 58.3% in sequestrations). MC on both EP was strongly associated with LDH (odds ratio = 9.76). Posterior corner MC had a significant association with LDH (72.72%, P < 0.001).

Conclusion:
DD seems to be a common thread in all patients (98.8%) with LDH, whereas EP damage seems to be specific pathway in a subset (38.3%). The study showed a significant degeneration of nucleus pulposus in most (98.8%) herniated discs. Compared with nonherniated discs, vertebral MC had a higher incidence in herniated discs (38%), and interestingly these were of subacute fatty type 2.
Plexiform intra-spinal neurofibromatosis in a young male with lower limb radiculopathy: A case report and review of literature
Authors: Naik Ashish Shankar , Murugan Chandhan , Anand Sri Vijay K S , Rajasekaran Shanmuganathan 
Published: August 2023

Abstract
Neurofibromatosis type 1 (NF-1) with extensive intraspinal involvement seldom presents with isolated radiculopathy. We report the case of a young male with NF-1 having dumbbell tumors along the entire extent of the spine presenting with isolated lower limb radiculopathy. The surgical goals for such tumors primarily involve symptom control, rather than “cure” of a specific lesion, with intervention typically reserved for lesions that significantly compress vital structures symptomatically. Clinical examination and magnetic resonance imaging clinched the symptomatic level in our patient to be L4–L5 and L5–S1, who significantly improved following a decompression surgery.
Posteriorly migrated epidural lumbar disc extrusion with contralateral neurodeficit: An unusual presentation
Authors: Thosar Sidheshwar S , Patel Bharat K , Reddy Mallidi M , Bapat Mihir R , Gujral Amandeep 
Published: August 2023

Abstract
The posterior epidural migration of lumbar disc herniation is a rare condition, and the overall reported incidence is 0.4%–1.04%. Most of these cases present with cauda equina syndrome or polyradiculopathy on ipsilateral side. We report a case of posterior epidural migration of lumbar disc causing contralateral neurodeficit. A 66-year-old gentleman presented with axial pain radiating to the left anterolateral thigh since 15 days after heavy weight lifting. Neurological examination revealed hypoesthesia over left L3 dermatome and left knee extensor weakness (Medical Research Council grade 3/5). Magnetic resonance imaging with contrast showed L2–L3 right-side extruded disc fragment migrated posteriorly in epidural space. Contralateral monoradiculopathy was an unusual presentation. Interlaminar decompression and discectomy were able to achieve complete neurological recovery at three months. To the best of our knowledge, this is the second case with contralateral neurodeficit due to posteriorly migrated lumbar disc herniation.
Minimal Invasive Approach for Rib Fractures
Authors: Martínez Arias Miguel Alejandro , Garcia Ulises Loyola , Omaña Toledo Juan Antonio , Mercado Sánchez Linda Sofia 
Published: August 2023

Background:
Current pathologies and the concepts applied for chest trauma, both for revision of thoracic cavity and to solve same traumatisms, have allowed to develop minimal surgery approach techniques for the resolution of multiple nosologies, thanks to their various benefits, currently this has been classified as a vanguard surgical technique worldwide.

Material and Methods:
Patients undergoing ribs fixation with minimal invasive technique, at ISSEMYM Medical Center, Thoracic Surgery Service, were analyzed according to age, gender, number of ribs fixed, days of hospital stay, days with endopleural tube, type of anesthesia, and complications. We present a series of cases with retrospective, descriptive design in a period of 72 months.

Results:
This is the largest case series reported for fixing ribs by minimal invasive approach, a final sample n = 103 was used, and favorable results and description of the same technique were described. The analyzed number of fixed ribs presented an average of 3.8 ribs fixed per patient. The average of hospital stay days was 5.08 days, after the procedure. Moreover, the oldest patient undergoing this procedure was 89 years old and the youngest was 23 years old.

Conclusions:
The technique of fixing ribs by minimal invasive approach continues to be a choice technique to reduce postoperative complications and reduce days of hospital stay, it is a reproducible, safe and pioneering technique for chest surgery, even in geriatric patients.
A Study to Assess the Risk of COVID-19 Infection in the Paediatric Age Group by Serosurvey in Four Blocks of the District Gwalior
Authors: Tiwari Ranjana , Mishra Vaibhav , Bansal Manoj , Diwakar Avadhesh , Khetan Rishika , Shukla Durgesh 
Published: August 2023

Introduction:
As it was expected that the upcoming wave of COVID-19, where children and young age group was thought to get affected the most, there was a need for finding the serological prevalence of COVID-19 infection among children. Hence, the present study had been conducted with the aim to assess the sero-prevalence of COVID-19 infection among children aged 1 year to <18 years in the families with and without a history of COVID-19 cases reported to health functionary in pre-identified rural and urban areas of Gwalior district.

Methodology:
The present study was a community-based, cross-sectional survey conducted for the period of 1 month i.e. August–September 2021 in Urban and Rural areas of Gwalior district. The study unit was children from 1 year to <18 years of age. Total sample of 400 children were included using purposive sampling procedure. Data collection was done using a questionnaire and blood samples of the participant were taken. Statistical analysis was done using the IBM SPSS Statistics V22.0 Chicago. P value was judged at 5% level of significance.

Results:
Among selected sample population Reverse Transcription Polymerase Chain Reaction testing was done in 222 families to any of the family members, out of which 116 (52.3%) belongs to rural area 106 (47.7%) belongs to urban area. Gender wise, seropositivity among male participants was 77.3% and 74.4% among female participants. The overall detected seropositivity in urban area (79%) was higher as compared to rural area (73%).

Conclusion:
SARS-CoV-2 seropositivity rate among children was high. There is urgent need for vaccination among the children to prevent development of complications, if develop infection. People must follow COVID-appropriate behavior and must receive full vaccination.
Study of Extramedullary Lymphoblastic Lymphoma (LBL) Diagnosed by Flowcytometric Immunophenotyping (FCI) on Fine Needle Aspirate (FNA) Sample—A Case Series of 18 Cases
Authors: Makde Manjiri M. , Kodate Purnima M. , Kamal Meherbano M. , Shroff Vrushali , Tijare Jayashree R. , Kumbhalkar Dinkar T. 
Published: August 2023

Background:
Lymphoblastic lymphoma (LBL) accounts for about 2% of all lymphomas. Recognition of T/B-LBL albeit of their rareness is very important as they present as localized diseases with low tumor burden. They can present both at nodal and extranodal sites. Limitation of diagnosis and classification of lymphoma on fine needle aspirate (FNA) can be minimized by clubbing it with flowcytometric immunophenotyping (FCI) to ensure diagnostic accuracy rapidly.

Aim:
Study of a series of 18 cases of LBL to assess the utility of FCI on FNA and effusion samples in extramedullary LBL.

Methods and Material:
FCI was done on FNA and effusion samples from 130 morphologically diagnosed/suspicious cases of lymphoreticular malignancy, followed by peripheral blood and bone marrow (BM) examination. The patients diagnosed to have B/T LBL, based on WHO 2017 classification, were selected for further analyses.

Results:
FCI of 130 cases showed 91 mature and 18 precursor lymphoid neoplasms. These 18 cases were from lymph nodes (11), pleural fluid (03), and soft tissue masses (04). Peripheral blood and BM of 15/18 cases were normal of which FCI revealed T-LBL (11) and B-LBL (04). Two cases (both T LBL) showed BM involvement (<25%), while one case of B-LBL which was misdiagnosed as mature lymphoma by immunohistochemistry (IHC) evolved as B ALL.

Conclusions:
Diagnosis of extramedullary B/T-LBL needs comprehensive evaluation of clinical presentation, cytomorphology, and immunophenotyping. Rapid and accurate diagnosis by FCI on FNA and effusion samples allows early therapeutic decisions, thereby avoiding leukemic dissemination.
Network traffic prediction model based on linear and nonlinear model combination
Authors: Lian Lian 
Published: August 2023

AbstractWe propose a network traffic prediction model based on linear and nonlinear model combination. Network traffic is modeled by an autoregressive moving average model, and the error between the measured and predicted network traffic values is obtained. Then, an echo state network is used to fit the prediction error with nonlinear components. In addition, an improved slime mold algorithm is proposed for reservoir parameter optimization of the echo state network, further improving the regression performance. The predictions of the linear (autoregressive moving average) and nonlinear (echo state network) models are added to obtain the final prediction. Compared with other prediction models, test results on two network traffic datasets from mobile and fixed networks show that the proposed prediction model has a smaller error and difference measures. In addition, the coefficient of determination and index of agreement is close to 1, indicating a better data fitting performance. Although the proposed prediction model has a slight increase in time complexity for training and prediction compared with some models, it shows practical applicability.
Penerapan Akuntansi Persediaan Barang Dagang Pada Online Shop Jumun.Id
Authors: Peilouw Christian Timotius , Oktavia Dwi Dayanti , Muliana Erna 
Published: August 2023

Abstract Inventory is the main component for the continuity of a business, so that regardless of the form of business, both small and large scale, inventory is a major asset owned by a business. For this reason, a rule or guideline is needed so that inventory can be managed properly. The purpose of this research is to find out how to apply merchandise inventory accounting to the jumun.id online shop. This type of research is qualitative. The results showed that the recording system at the jumun.id online shop is periodic and this is in accordance with PSAK No. 14 and the scoring system using FIFO. Keywords— FIFO, Periodic, InventoryAbstrakPersediaan merupakan komponen utama bagi keberlangsungan suatu usaha, sehingga apapun bentuk usahanya baik skala kecil ataupun skala besar persediaan merupakan asset besar yang dimiliki oleh suatu usaha. Untuk itu diperlukan sebuah aturan atau pedoman agar persediaan dapat dikelola dengan baik. Tujuan penelitian ini adalah untuk mengetahui bagaimana penerapan akuntansi persediaan barang dagang pada online shop jumun.id. Jenis penelitian ini adalag kualitatif. Hasil penelitian diperoleh bahwa sistem pencatatan pada online shop jumun.id adalah periodic dan ini sesuai dengan PSAK No 14 dan ssstem penilaian dengan menggunakan FIFO. Kata kunci— Persediaan, Periodik, FIFO
Deep Direct Discriminative Decoders for High-dimensional Time-series Data Analysis
Authors: Rezaei Mohammad , Popovic Milos , Eden Uri , Lankarany Milad , Yousefi Ali 
Published: August 2023

The state-space models (SSMs) are widely utilized in the analysis of time-series data. SSMs rely on an explicit definition of the state and observation processes. Characterizing these processes is not always easy and becomes a modeling challenge when the dimension of observed data grows or the observed data distribution deviates from the normal distribution. Here, we propose a new formulation of SSM for high-dimensional observation processes with a heavy-tailed distribution. We call this solution the deep direct discriminative process (D4). The D4 brings deep neural networks’ expressiveness and scalability to the SSM formulation letting us build a novel solution that efficiently estimates the underlying state processes through high-dimensional observation signal.We demonstrate the D4 solutions in simulated and real data such as Lorenz attractors, Langevin dynamics, random walk dynamics, and rat hippocampus spiking neural data and show that the D4’s performance precedes traditional SSMs and RNNs. The D4 can be applied to a broader class of time-series data where the connection between high-dimensional observation and the underlying latent process is hard to characterize.
Simulating heat and CO2 fluxes in Beijing using SUEWS V2020b: sensitivity to vegetation phenology and maximum conductance
Authors: Zheng Yingqi , Havu Minttu , Liu Huizhi , Cheng Xueling , Wen Yifan , Lee Hei Shing , Ahongshangbam Joyson , Järvi Leena 
Published: August 2023

Abstract. The Surface Urban Energy and Water Balance Scheme (SUEWS) has recently been introduced to include a bottom-up approach to modeling carbon dioxide
(CO2) emissions and uptake in urban areas. In this study, SUEWS is evaluated against the measured eddy covariance (EC) turbulent fluxes of
sensible heat (QH), latent heat (QE), and CO2 (FC) in a densely built neighborhood in Beijing. The
model sensitivity to maximum conductance (gmax) and leaf area index (LAI) is examined. Site-specific gmax is obtained from
observations over local vegetation species, and LAI parameters are extracted by optimization with remotely sensed LAI obtained from a Landsat 7 data product. For
the simulation of anthropogenic CO2 components, local traffic and population data are collected. In the model evaluation, the mismatch
between the measurement source area and simulation domain is also considered. Using the optimized gmax and LAI, the modeling of heat fluxes is noticeably improved, showing higher correlation with observations, lower
bias, and more realistic seasonal dynamics of QE and QH. The effect of the gmax adjustment is more significant
than the LAI adjustment. Compared to heat fluxes, the FC module shows lower sensitivity to the choices of gmax and LAI. This
can be explained by the low relative contribution of vegetation to the net FC in the modeled area. SUEWS successfully reproduces the
average diurnal cycle of FC and annual cumulative sums. Depending on the size of the simulation domain, the modeled annual accumulated
FC ranges from 7.4 to 8.7 kgCm-2yr-1, compared to 7.5 kgCm-2yr-1 observed by EC. Traffic is
the dominant CO2 source, contributing 59 %–70 % to the annual total CO2 emissions, followed by human metabolism
(14 %–18 %), buildings (11 %–14 %), and CO2 release by vegetation and soil respiration (6 %–10 %). Vegetation
photosynthesis offsets only 5 %–10 % of the total CO2 emissions. We highlight the importance of choosing the optimal LAI
parameters and gmax when SUEWS is used to model surface fluxes. The FC module of SUEWS is a promising tool in quantifying
urban CO2 emissions at the local scale and therefore assisting in mitigating urban CO2 emissions.