bluuebunny/crossref_metadata_2025_split huggingface dataset:
KAJIAN YURIDIS PEMAKAMAN PROTOKOL KESEHATAN DITINJAU DARI HAK UNTUK MENDAPATKAN KEBENARAN INFORMASI PASAL 14 AYAT (1) UNDANG – UNDANG HAK ASASI MANUSIA
Authors: Retno Evi , Kuswanto Heru 
Published: July 2023

A The Government's efforts in the Covid-19 pandemic issue regarding the issue of public dissatisfaction with the handling carried out by several unscrupulous medical teams in this pandemic in various existing hospitals. Many members of the community feel dissatisfied and agree with having experienced some kind of coercive action, including when they are going to be isolated in hospital based only on the results of their suspicion or concern that they will be exposed to the Covid-19 Virus. In other cases, the medical team forced the bodies of people who died from non-Covid-19 diseases to be buried following the covid-19 funeral protocol. Community complaints related to determining the status of ODP, PDP and OTG patients. Many patients under surveillance (PDP) who died were buried according to the Covid-19 protocol, but the swab test results were negative. The solution to cases like this did not happen, the hospital should have accelerated the examination of the swab test in the laboratory. Many incidents of bodies were buried with the Covid protocol but the results of the swab test were negative, causing a misunderstanding between the hospital and the family, and also so that the family does not consider funerals according to the Covid-19 protocol as a matter of human rights (HAM). The reason is, there were those who were declared ODP and PDP died during the treatment process at the hospital. But the results of the swab test are yet to come out. apologized that the hospital immediately conducted a swab test on the patient. The laboratory must also prioritize all those lying in the hospital. The family did not accept it because their relatives were buried according to the Covid-19 protocol, because when ODP and PDP were admitted to the hospital, the patient was immediately asked to sign ready to follow the Covid-19 protocol, even though it was not certain that the patient was sick because of Covid-19. It's been buried and then the results come out. Things like this are definitely obtained from the community. negative family of covid-19 but why buried according to covid-19 protocol. Because the community also needs certainty, not only because of suspicion, then the patient immediately serves covid-19 and the patient should not be left waiting for days for the results of the swab test.
Keywords: Covid-19, Funeral, Human Rights, protocol,patient
ANALISIS TERHADAP PUTUSAN MA NO.482K/TUN/2021 TERKAIT SURAT KEPUTUSAN GUBERNUR JAWA TENGAH NO.590/20TAHUN 2021
Authors: Boediningsih Widyawati , Tandiono Sudargo 
Published: July 2023

Mining and the construction of public facilities of course require land acquisition before carrying out activities. However, conflicts of interest or legal issues are often encountered, both from the public who do not agree or there are discrepancies in the decrees issued by the government, both regional and central. Although the dispute can be resolved by filing a lawsuit in the State Administrative Court. However, there is still dissatisfaction from the aggrieved parties so that this research will assist in analyzing the Supreme Court Decision Number 482 K/TUN/2021 related to the dispute over the construction of the Bener dam in Wadas Village, Purworejo, Central Java.
Keywords: IUP, Mining, Supreme Court Decision, Andesite
KEBIJAKAN UU NO 1 TAHUN 2022 MENGENAI PERIMBANGAN KEUANGAN ANTAR PUSAT DAN DAERAH PASCA REFORMASI
Authors: Ifa Siti Hudza , Pratama Rizky , Arwanto Bambang 
Published: July 2023

After the amendment, Regulation Number 25 of 1999 concerning Financial Balance between the Center and the Regions, but after the amendment of Regulation Number 33 of 2004 concerning Financial Balance between the Center and the Regions, the allocation of asset adjustments has moved to the dispersion of some normal assets in the area . The issue studied is where regional finance can increase and find sources of income which are expected to complement its independence as a result of the implementation of decentralization guidelines as adopted by the 1945 Constitution. The exploration technique used is essential literature studies, selected regulations and materials. tertiary legal materials, and the examination carried out is subjective standardization. With the issuance of the regulation on Fiscal Balance between the Center and the Regions after the amendment, it shows very large results for the implementation of provincial independence, considering that regional supporting sources are generally not solely based on PAD (Regional Revenue) results, but the regions also have different sources of initial funding from the regions, formerly only enjoyed by the central government.
Keywords: Policy, Regional Finance, Post Reform
PERLINDUNGAN HUKUM BAGI PEMBELI CONDOTEL MELALUI PERJANJIAN PENGIKATAN JUAL BELI
Authors: Suwardi  , Boediningsih Widyawati 
Published: July 2023

Efforts to protect the law for buyers of condotel units as consumers from developers, the legal aspects of buying and selling transfers must be fully understood by buyers. In the process of buying and selling fixed objects such as land, houses, apartments or other properties, they are bound by an agreement. The Sale and Purchase Binding Agreement (PPJB) is made to carry out a temporary binding before the official Sale and Purchase Deed (AJB) is made before the Land Deed Making Officer (PPAT). Generally, the Sale and Purchase Binding Agreement (PPJB) is made privately for a certain reason, such as the payment of the price has not been paid off. With the Sale and Purchase Binding Agreement, there are still frequent losses suffered by the buyer. This study aims to determine the legal protection for condotel buyers through PPJB. The method used in this paper is normative juridical, which refers to the legislation and literature study.The results of this study, that the Sale and Purchase Binding Agreement has been prepared by the developer or legal representative as a standard agreement whose contents are not in accordance with the terms of the standard agreement. Prior to the signing of the Sale and Purchase Agreement, prospective buyers are usually given the opportunity to read and study the draft of the Sale and Purchase Binding Agreement with the guidance of an officer.
Keywords: Legal Protection, Buyers, Condotel, PPJB.
PERTANGGUNGJAWABAN PIDANA PELAKU PROSTITUSI ONLINE MENGGUNAKAN SARANA APLIKASI MICHAT
Authors: Jagad Rony Piwulang , Hartoyo  
Published: July 2023

The main problem of the research is how is the criminal liability of online prostitutes using the application. In the main issue, the problem will be formulated in several sub-problems, namely: 1) How is the legal regulation of online prostitution using the Michat application?, 2) How are the criminal acts of online prostitution using the Michat application? ?, 3) how is the criminal liability for online prostitution actors using the michat application?. This research uses normative legal research methods and this research is descriptive. The results of the study show that: 1) The legal basis for ensnaring perpetrators of online prostitution are articles 282 and 289 of the Criminal Code, article 27 paragraph (1) in conjunction with article 45 paragraph (1) of Law number 11 of 2008 concerning ITE and articles 29, 30 of the Law - Law number 44 of 2008 concerning Pornography. 2) The elements of online prostitution are subjective elements, objective elements and unlawful acts. 3) Criminal liability in the form of imprisonment, fines and social sanctions.
Keyword :Criminal Liability, Online Prostitution, Michat
Synthesis and anti-tumor activity of piperonal substituted chalcone
Authors: Muhammad Zahatu , Yau Jamilu , Zezi Abdulqadir U. , Magaji Mohammed G. , Hamza Asmau N. 
Published: July 2023

Objectives:
Chalcones have been identified as potential antitumor agents with a novel target, the tubulin. The aim of the study was to synthesize a piperonal substituted chalcone and evaluate its in vivo antitumor activity.

Materials and Methods:
Piperonal substituted chalcone was synthesized using Claisen-Schmidt condensation and characterized using various spectroscopic techniques. The lethal dose (LD50) of the synthesized compound was estimated using OECD-425 guidelines in rats. Antitumor activity of the synthesized compound was evaluated on 1-methyl nitrosourea (MNU)-induced mammary tumor in female Wistar rats. Histological evaluation was used to confirm tumor induction and assess treatment with the synthesized compound. The possible mechanism of action of the synthesized compound was elucidated in silico using molecular docking.

Results:
The compound was synthesized and named C2. C2 was found to be relatively safe with LD50 >2000 mg/kg orally. Moreover, C2 exhibited remarkable antitumor activity, at all the tested doses in a dose dependent manner. Histological evaluation of the MNU-induced mammary tumor rats treated with C2 displayed fewer signs of hyperplasia and small numbers of connective tissue with larger lobules when compared with the untreated group. In silico tubulin-binding interactions revealed that the kinetics of C2 binding to tubulin was like that of colchicine. Comparison of crystal structures of tubulin-C2 and tubulin-colchicine complexes showed that the binding mode of C2 to tubulin was like that of colchicine to tubulin and produced the same conformational changes on the tubulin structure as colchicine.

Conclusion:
The synthesized chalcone demonstrated remarkable antitumor activities in MNU-induced mammary tumors in rats possibly through inhibition of tubulin polymerization.
Utility of mutation-specific immunohistochemical markers for predicting post-induction remission among acute myeloid leukemia patients – A prognostic test accuracy study
Authors: Muralidaran Manjubala , Kayal Smita , Harichandrakumar K. T. , Kar Rakhee 
Published: July 2023

Objectives:
Various prognostically important genetic mutations are associated with acute myeloid leukemia (AML). Studies have found correlation between these mutations and expression of certain abnormal proteins in the tumor cells by immunohistochemistry (IHC). Common genetic mutations are nucleophosmin 1 (NPM1) and FMS like tyrosine kinase 3 (FLT3). This study aimed at studying the prognostic utility of surrogate IHC for these mutations-NPM1 IHC for NPM1 mutation, whereas C-X-C Chemokine Receptor type 4 (CXCR4) and Cluster of Differentiation 123 (CD123) IHC for FLT3 mutation in AML patients.

Material and Methods:
This was a prognostic test accuracy study done in a tertiary care centre over a period of two years (2018–2020) under two subgroups: who attained remission (remission group) and who failed to achieve remission (not in remission group) after induction therapy. Prognostic IHC markers were performed on the diagnostic bone marrow biopsy.

Results:
There were 70 cases in remission and 49 cases not in remission with median age of 32 and 31 years, respectively. Median total leucocyte count was significantly more in remission group (P = 0.02). AML subtype and cytogenetics wise, remission group, had significantly more M3 and M4 subtypes and translocations, while not in remission group had more M2 and M1 and more of normal and complex cytogenetics (P = 0.01 and 0.03, respectively). NPM1 and FLT3 mutation did not show significant association with remission status. IHC for NPM1, CXCR4, and CD123 was performed in the diagnostic bone marrow biopsy. Loss of nuclear localization of NPM1 and CXCR4 positivity by IHC was more in remission than not in remission (34.3% vs. 28.6% and 54.3% vs. 44.9%, respectively) which was not statistically significant. The expression of NPM1, CXCR4, and CD123 IHC had low sensitivity (34%, 54%, and 4.3%, respectively) to predict remission status. NPM1 IHC was highly significantly associated with NPM1 mutation and had high sensitivity (89%) and specificity (86%) to predict NPM1 mutation whereas CXCR4 and CD123 had low sensitivity, specificity to predict FLT3 mutation.

Conclusion:
NPM1 IHC can be used as a surrogate to predict NPM1 mutation whereas CXCR4 and CD123 are not effective surrogates to predict FLT3 mutation.
ANALISIS KEMAMPUAN BERPIKIR KREATIF SISWA KELAS VII SMP NEGERI 65 MALUKU TENGAH PADA MATERI SUHU DAN KALOR
Authors: Mulder Wilem Rilexen S P , Siswanto Joko 
Published: July 2023

This research aims asa preliminary study to determine the ability to think creatively in physics learning using a correlational form with a quantitative approach and analyzed descriptively. The research subject is class VII SMP Negeri 65 Central Maluku, Central Maluku Regency. The data collection stage uses a test instrument containing description questions that have been designed in line with creative thinking indicators. Based on the results of the study, the average score of students' creative thinking skills was 54.94. with a high percentage of 1 student (5.89%). 11 students (70.59%) moderate, and 4 students (23.52%) low with the achievement level of each indicator 95% Fluency, 70% Flexibility, 75% Originality, 68% Elaboration, and 66% Evaluation. The conclusions of this study indicate the tendency of students' creative thinking abilities to be in the medium and low categories. The implication of this preliminary study is that physics learning media will be developed by utilizing technology by STEM-based interactive web with ESD insight on temperature and heat material to improve students' creative thinking skills
INFORMATION FUNCTION OF DIGITAL MONEY
Authors: Коробейников Д.А. 
Published: July 2023

Цель статьи – проанализировать возможные изменения функций денег, связанные с появлением новой формы фиатных денег – цифровых валют центральных банков. Выдвинута гипотеза, что развитие цифровых финансовых технологий не меняет сущность традиционных функций денег, но усиливает их информационное содержание. Научная новизна исследования связана с дополнением информационной функции цифровых денег новыми институциональными и технологическими особенностями, проявляющимися в компьютерной алгоритмизации инструментов контроля денежного обращения и целевых параметров транзакций, а также автоматизации их исполнения в форме смартконтрактов на платформе цифрового рубля. Обоснованы возможные информационные эффекты для платежных систем, финансовых посредников, государства и экономических субъектов.
The purpose of the article is to analyze possible changes in the functions of money associated with the emergence of a new form of fiat money - digital currencies of central banks. A hypothesis has been put forward that the development of digital financial technologies does not change the essence of the traditional functions of money, but enhances their information content. The scientific novelty of the study is related to the addition of the information function of digital money with new institutional and technological features, which manifests itself in computer algorithmization of money circulation control tools and target parameters of transactions, as well as automation of their execution in the form of smart contracts on the digital ruble platform. Possible informational effects for payment systems, financial intermediaries, the state and economic entities are substantiated.
ECONOMIC FOUNDATIONS OF EDUCATIONAL PROGRAM MANAGEMENT IN THE HIGHER EDUCATION SYSTEM
Authors: Мичкова О.А. 
Published: July 2023

Цель статьи – исследование процессов управления образовательной программой, включая процессы проектирования дизайна, реализации, модернизации, для обеспечения повышения ее качества, эффективности, конкурентоспособности. Управление образовательной программой представляет собой систему содержательных, ресурсных, оценочных компонентов, которые образуют целостность учебно-воспитательного процесса на всех уровнях. Научная новизна работы заключается в теоретическом обосновании подходов к процессу управления образовательными программами в системе высшей школы и определении организационно-экономических особенностей, которые систематизированы по параметрам: управление содержанием; управление процессами; управление ресурсами; управление контингентом; управление финансами; управление качеством. Объективность и достоверность полученных результатов обеспечивается используемой методологической основой исследования, в основе которой общенаучные методы познания анализа и синтеза.
The purpose of the article is to study the management processes of the educational program, including the processes of design, implementation, modernization, to ensure the improvement of its quality, efficiency, competitiveness. The management of the educational program is a system of content, resource, evaluation components that form the integrity of the educational process at all levels. The scientific novelty of the work consists in the theoretical substantiation of approaches to the process of managing educational programs in the higher school system and the definition of organizational and economic features, which are systematized by parameters: content management; process management; resource management; contingent management; financial management; quality management. . The objectivity and reliability of the results obtained is ensured by the chosen methodological basis of the study, which is based on general scientific methods of cognition analysis and synthesis
FEATURES OF STATE REGULATION OF TRADE ACTIVITIES IN INDIA
Authors: Смирнова О.В. 
Published: July 2023

Цель статьи – исследовать инструменты государственного регулирования торговой деятельности в современной Индии. Особенностью институциональной структуры регулирования торговли в Индии является значительная роль неправительственных и некоммерческих организаций, а также наличие специальных государственных агентств индийского правительства, осуществляющих содействие в выращивании, обработке и реализации ключевых для индийской экономики плантационных культур, таких как чай, сахар, табак, каучук и др. В статье рассмотрена система правовых актов, регламентирующих торговую деятельность в Индии, а также особенности регулирования цен на основные (жизненно-необходимые) товары. Научная новизна заключается в систематизации институтов и экономико-правовых инструментов государственного регулирования торговли в Индии.
The purpose of the article is to explore the instruments of state regulation of trading activities in modern India. A feature of the institutional structure of trade regulation in India is the significant role of non-governmental and nonprofit organizations, as well as the presence of special state agencies of the Indian government that assist in the cultivation, processing and sale of key plantation crops for the Indian economy, such as tea, sugar, tobacco, rubber, etc. The system of legal acts regulating trade activities in India, as well as the peculiarities of regulating prices for basic (vital) goods are considered. Scientific novelty lies in the systematization of institutions and economic and legal instruments of state regulation of trade in India.
SYSTEMIC IMPROVEMENT OF THE RUSSIAN ECONOMY Part 1. Introduction to the Russian economic security problems at the present stage
Authors: Ворожихин В.В. , Захаров В.К. 
Published: July 2023

В статье рассматриваются проблемы сложной экономической ситуации в России, сложившейся после непрерывного расширения системы экономических санкций и фактического перехода к экономической войне стран объединенного Запада после начала спецоперации на Украине. Россия оказалась на пути вытеснения экономики в ОПК. Чтобы не повторить неудачу СССР, необходимы новые решения, некоторые из которых реализованы в форме Координационных советов при Правительстве России. Несмотря на принципиальные преимущества объединенного Запада в сфере контроля глобальной экономики и новых технологий, создание решений для поддержания стратегической автономии, технологической независимости и экономической конкурентоспособности возможно и необходимо при всей сложности их разработки. Ключом к ним является повышение системности и детализации экономических исследований и глубины знаний. Один из важных этапов – завершение реформ российской науки, переход к современной системе оценки результатов научной деятельности, который с неизбежностью требует разработки новых инструментов организации научных коммуникаций и оценки научной деятельности.
The article analyzes the problems of the difficult economic situation in Russia, which has developed after the continuous expansion of the system of economic sanctions and the actual transition to economic war of the countries of the united West after the start of a special operation in Ukraine. Russia was on the way to oust the economy in the defense industry. In order not to repeat the failure of the USSR, new solutions are needed, some of which are implemented in the form of Coordination Councils under the Government of Russia. Despite the fundamental advantages of the united West in the field of control of the global economy and new technologies, the creation of solutions to maintain strategic autonomy, technological independence and economic competitiveness is possible and necessary, with all the complexity of their development. The key to these is to increase the consistency and detail of economic research and the depth of knowledge. One of the important stages is the completion of the reforms of Russian science, the transition to a modern system for assessing research and scientific results, which inevitably requires the development of new tools for organizing scientific communications and assessing scientific activities
Development of an Algorithm for Multicriteria Optimization of Deep Learning Neural Networks
Authors: Alexandrov Islam A. , Kirichek Andrey V. , Kuklin Vladimir Z. , Chervyakov Leonid M. 
Published: July 2023

Nowadays, machine learning methods are actively used to process big data. A promising direction is neural networks, in which structure optimization occurs on the principles of self-configuration. Genetic algorithms are applied to solve this nontrivial problem. Most multicriteria evolutionary algorithms use a procedure known as non-dominant sorting to rank decisions. However, the efficiency of procedures for adding points and updating rank values in non-dominated sorting (incremental non-dominated sorting) remains low. In this regard, this research improves the performance of these algorithms, including the condition of an asynchronous calculation of the fitness of individuals. The relevance of the research is determined by the fact that although many scholars and specialists have studied the self-tuning of neural networks, they have not yet proposed a comprehensive solution to this problem. In particular, algorithms for efficient non-dominated sorting under conditions of incremental and asynchronous updates when using evolutionary methods of multicriteria optimization have not been fully developed to date. To achieve this goal, a hybrid co-evolutionary algorithm was developed that significantly outperforms all algorithms included in it, including error-back propagation and genetic algorithms that operate separately. The novelty of the obtained results lies in the fact that the developed algorithms have minimal asymptotic complexity. The practical value of the developed algorithms is associated with the fact that they make it possible to solve applied problems of increased complexity in a practically acceptable time. Doi: 10.28991/HIJ-2023-04-01-011 Full Text: PDF