bluuebunny/crossref_metadata_2025_split huggingface dataset:
Software-based quantitative CT analysis to predict the growth trend of persistent nonsolid pulmonary nodules: a retrospective study
Authors: Borghesi Andrea , Coviello Felice Leopoldo , Scrimieri Alessandra , Ciolli Pietro , Ravanelli Marco , Farina Davide 
Published: May 2023

Abstract
Purpose
Persistent nonsolid nodules (NSNs) usually exhibit an indolent course and may remain stable for several years; however, some NSNs grow quickly and require surgical excision. Therefore, identifying quantitative features capable of early discrimination between growing and nongrowing NSNs is becoming a crucial aspect of radiological analysis. The main purpose of this study was to evaluate the performance of an open-source software (ImageJ) to predict the future growth of NSNs detected in a Caucasian (Italian) population.

Material and methods
We retrospectively selected 60 NSNs with an axial diameter of 6–30 mm scanned with the same acquisition-reconstruction parameters and the same computed tomography (CT) scanner. Software-based analysis was performed on thin-section CT images using ImageJ. For each NSNs, several quantitative features were extracted from the baseline CT images. The relationships of NSN growth with quantitative CT features and other categorical variables were analyzed using univariate and multivariable logistic regression analyses.

Results
In multivariable analysis, only the skewness and linear mass density (LMD) were significantly associated with NSN growth, and the skewness was the strongest predictor of growth. In receiver operating characteristic curve analyses, the optimal cutoff values of skewness and LMD were 0.90 and 19.16 mg/mm, respectively. The two predictive models that included the skewness, with or without LMD, exhibited an excellent power for predicting NSN growth.

Conclusion
According to our results, NSNs with a skewness value > 0.90, specifically those with a LMD > 19.16 mg/mm, should require closer follow-up due to their higher growth potential, and higher risk of becoming an active cancer.
The comparative constitutional compliance database
Authors: Gutmann Jerg , Metelska-Szaniawska Katarzyna , Voigt Stefan 
Published: May 2023

AbstractThis article introduces a novel database that measures governments’ compliance with national constitutions. It combines information on de jure constitutional rules with data on their de facto implementation. The individual compliance indicators can be grouped into four categories that we aggregate into an overall indicator of constitutional compliance: property rights and the rule of law, political rights, civil rights, and basic human rights. The database covers 175 countries over the period 1900 to 2020 and can be used by researchers interested in studying the determinants or the effects of (non)compliance with constitutions. Our investigation of the stylized facts of constitutional compliance reveals a long-term increase in compliance, which occurred primarily around the year 1990. The Americas experienced the steepest increase in compliance, but also Africa and Europe improved particularly at the end of the Cold War. Democracies – particularly those with parliamentary and mixed systems – show more constitutional compliance than nondemocracies, among which military dictatorships perform the worst. Constitutional design also matters: Constitutions that allow for the dismissal of the head of state or government for violating constitutional rules are being complied with more.
Selected Aspects of Non orthogonal Multiple Access for Future Wireless Communications
Authors: Flizikowski Adam , Marciniak Tomasz , Wysocki Tadeusz A. , Oyerinde Olutayo 
Published: May 2023

AbstractIn this paper overview of recent selected works that deal with novel directions in which Non orthogonal multiple access (NOMA) research is progressing is presented. These include the cell-free NOMA, deep learning extensions and optimizations of NOMA, energy optimization and task offloading with mobile-edge computing, NOMA and physical layer security, as well as virtualization, centralized-RAN aspects. All these are hot issues towards deployments of NOMA in the designs of beyond 5G and 6th generation (6G) wireless communication networks. Even though 3rd Generation Partnership Project (3GPP) has not yet made the decision regarding which NOMA techniques should be adopted, it seems like researchers already indicate clearly that NOMA has important place in the future network deployments based on ultra-density, novel 5G use-cases (massive machine type communications, ultra-reliable low latency communications). This paper highlights the most promising directions for NOMA research. The paper is summarized with necessary steps that are required to get NOMA into practical usage.
Approaching Study on the Relationship Between Saccharomyces cerevisiae Production of Tyrosol, Hydroxytyrosol, and Melatonin with Volatile Compounds in Fermented Must
Authors: Gonzalez-Ramirez Marina , Marin-Torres Maria Mar , Gallardo-Fernandez Marta , Planells-Carcel Andres , Bisquert Ricardo , Valero Eva , Ubeda Cristina , Troncoso Ana Maria , Garcia-Parrilla Maria Carmen 
Published: May 2023

AbstractYeasts are feasible and effective bioreactors and, therefore, there is a great interest in their industrial employment for the production of a wide range of molecules. In this study, the production by Saccharomyces cerevisiae of bioactive compounds such as hydroxytyrosol (HT), tyrosol (TYR) and melatonin (MEL) vs. volatile compounds in fermented must was studied. The concentration of the bioactive compounds HT and MEL in fermented must employing different yeast strains revealed that the higher the concentrations, the lower the amount of volatile compounds determined. This inverse correlation was especially remarkable with respect to the production of higher alcohols, especially 2-phenylethanol (2-PE) and esters. Furthermore, the employment of a modified Aro4pK229LS. cerevisiae QA23 yeast strain which overproduces HT, gave rise to fermented must also higher in 2-PE and their corresponding esters but with an outstanding less presence of other important esters such as ethyl hexanoate and ethyl octanoate. Both premises could point out that S. cerevisiae might have different approaches to handling cell stress/toxicity due to their nitrogen metabolism. One detoxifying pathway could be through the production of higher alcohols and these in turn to esters and the other be more related to synthesizing antioxidant molecules such as MEL and HT.
Preventing and Treating Infection in Reverse Total Shoulder Arthroplasty
Authors: Markes Alexander R. , Bigham Joseph , Ma C. Benjamin , Iyengar Jaicharan J. , Feeley Brian T. 
Published: May 2023

Abstract

Purpose of Review
Periprosthetic infection after shoulder arthroplasty is relatively uncommon though associated with severe long-term morbidity when encountered. The purpose of the review is to summarize the recent literature regarding the definition, clinical evaluation, prevention, and management of prosthetic joint infection after reverse shoulder arthroplasty.

Recent Findings
The landmark report generated at the 2018 International Consensus Meeting on Musculoskeletal Infection has provided a framework for diagnosis, prevention, and management of periprosthetic infections after shoulder arthroplasty. Shoulder specific literature with validated interventions to reduce prosthetic joint infection is limited; however existing literature from retrospective studies and from total hip and knee arthroplasty allows us to make relative guidelines. One and two-stage revisions seem to demonstrate similar outcomes; however, no controlled comparative studies exist limiting the ability to make definitive recommendations between the two options.

Summary
We report on recent literature regarding the current diagnostic, preventative, and treatment options for periprosthetic infection after shoulder arthroplasty. Much of the literature does not distinguish between anatomic and reverse shoulder arthroplasty, and further high-level shoulder specific studies are needed to answer questions generated from this review.
Recent progress of in-fiber WGM microsphere resonator
Authors: Yang Yong , Wang Zijie , Zhang Xiaobei , Zhang Qi , Wang Tingyun 
Published: May 2023

AbstractIn-fiber whispering gallery mode (WGM) microsphere resonators have received remarkable attention due to the superiorities of compact structure, high stability and self-alignment. As an in-fiber structure, WGM microsphere resonators have been demonstrated in various applications, such as sensors, filters and lasers, which have significant impacts on modern optics. Herein, we review recent progress of in-fiber WGM microsphere resonators, which involve fibers of diverse structures and microspheres of different materials. First, a brief introduction is given to in-fiber WGM microsphere resonators, from structures to applications. Then, we focus on recent progresses in this field, including in-fiber couplers based on conventional fibers, capillaries and micro-structure hollow fibers, and passive/active microspheres. Finally, future developments of the in-fiber WGM microsphere resonators are envisioned.
Graphical Abstract
The Role of Higher Education Institutions (HEI) in Academic Spin-off Creation: A Cooperation Perspective
Authors: Pacheco Ana , Franco Mário 
Published: May 2023

AbstractCooperation between Higher Education Institutions and Enterprises (HEI-E-C) is extremely relevant in regional economic development. Therefore, this study aims to understand the role of HEI in academic spin-off creation. To achieve this objective, we adopted the qualitative approach (case study method) and focused on a cooperation relation involving a Portuguese HEI and two academic spin-offs. For data collecting, several interviews with key informants and direct observation were used. Content analysis of the interviews with founders of these academic spin-offs and lecturers teaching the curricular unit of entrepreneurship in the HEI studied, the results identified some essential aspects to understand this type of cooperation (HEI-E): (1) the role of academic entrepreneurship and its importance in the growth of spin-offs for regional economic growth, (2) the influence of academic entrepreneurs’ characteristics in the process of creating a spin-off, and (3) academic motivations to create spin-offs and the benefits of cooperation with HEIs. This study also presents implications for theory and educational and business practice.
Pain and mild cognitive impairment among adults aged 50 years and above residing in low- and middle-income countries
Authors: Smith Lee , López Sánchez Guillermo F. , Shin Jae Il , Soysal Pinar , Pizzol Damiano , Barnett Yvonne , Kostev Karel , Jacob Louis , Veronese Nicola , Butler Laurie , Odell-Miller Helen , Bloska Jodie , Underwood Benjamin R. , Koyanagi Ai 
Published: May 2023

Abstract
Background
Previous studies on the association between pain and cognitive decline or impairment have yielded mixed results, while studies from low- and middle-income countries (LMICs) or specifically on mild cognitive impairment (MCI) are scarce. Thus, we investigated the association between pain and MCI in LMICs and quantified the extent to which perceived stress, sleep/energy problems, and mobility limitations explain the pain/MCI relationship.

Methods
Data analysis of cross-sectional data from six LMICs from the Study on Global Ageing and Adult Health (SAGE) were performed. MCI was based on the National Institute on Aging-Alzheimer's Association criteria. "Overall in the last 30 days, how much of bodily aches or pain did you have?” was the question utilized to assess pain. Associations were examined by multivariable logistic regression analysis and meta-analysis.

Results
Data on 32,715 individuals aged 50 years and over were analysed [mean (SD) age 62.1 (15.6) years; 51.7% females]. In the overall sample, compared to no pain, mild, moderate, and severe/extreme pain were dose-dependently associated with 1.36 (95% CI = 1.18–1.55), 2.15 (95% CI = 1.77–2.62), and 3.01 (95% CI = 2.36–3.85) times higher odds for MCI, respectively. Mediation analysis showed that perceived stress, sleep/energy problems, and mobility limitations explained 10.4%, 30.6%, and 51.5% of the association between severe/extreme pain and MCI.

Conclusions
Among middle-aged to older adults from six LMICs, pain was associated with MCI dose-dependently, and sleep problems and mobility limitations were identified as potential mediators. These findings raise the possibility of pain as a modifiable risk factor for developing MCI.
Sintering behaviour of 3D-printed 18K 5N gold alloy by binder jetting: a preliminary study
Authors: Mariani Marco , Vario Tiziana , Salaheldin Karim , Annoni Massimiliano , Lecis Nora 
Published: May 2023

AbstractBinder jetting is a versatile additive manufacturing technique suitable to produce alloys that are difficult to obtain by powder bed fusion techniques, such as precious metals, due to their high reflectivity and thermal conductivity. In this study, a 18K 5N gold alloy powder was employed in the printing process. Different heat treatments and densification processes were employed to achieve final-stage sintering and remove residual porosity, whilst controlling the evolution of copper oxides by reduction with hydrogen and graphite. Powder, green and sintered samples were characterised at the microstructural level by X-ray diffraction, microscopy and energy dispersive X-ray spectroscopy to assess phase transitions and secondary-phase formation. Oxide-free components with a final relative density above 90% were achieved by densification at 830 °C combined with carbon- and CO-induced reduction of tenorite and cuprite. The optimal manufacturing route was chosen to produce a bezel, as a case study for the adoption of this technique in the jewellery industry.
A Systematic Review and Meta-analysis of Online Mindfulness-Based Interventions for University Students: An Examination of Psychological Distress and Well-being, and Attrition Rates
Authors: Alrashdi Duaa H. , Chen Kayla K. , Meyer Carly , Gould Rebecca L. 
Published: May 2023

AbstractThere are increasing concerns about university students’ mental health with mindfulness-based interventions (MBIs) showing promising results. The effect of MBIs delivered digitally to a broad range of university students and study attrition rates remain unclear. This review aimed to explore the effectiveness of online MBIs on university students’ mental health, academic performance and attrition rate of online MBIs. Four databases were searched; both randomised and non-randomised controlled trials were included. Outcomes included mental health-related outcomes and academic performance. Twenty-six studies were identified with outcomes related to mental health. When compared with non-active controls, small to medium statistically significant effect sizes in favour of online MBIs were found for depression, stress, anxiety, psychological distress and psychological well-being at post-intervention. However, these benefits were not seen when online MBIs were compared to active controls and other treatments at post-intervention or follow-up. University students in online MBI arms were more likely to drop out compared to non-active controls and active controls, but no differences were found compared to other treatments. Generally, the included studies’ risk of bias was moderate to high. Online MBIs appear beneficial for improving university students’ mental health when compared to non-active controls post-intervention, but not active controls or other treatments. Findings related to active controls and other treatments should be interpreted with caution due to the small number of studies, the small number of participants in included studies and the degree of heterogeneity in effect sizes.
Logistics dynamic information retrieval based on blockchain data security model
Authors: Yang Hua 
Published: May 2023

AbstractThis study presents blockchain technology to integrate the time attribute of Internet of Things data and the time stamp of blockchain, and proposes a data retrieval solution based on dynamic information retrieval. Analyze and reorganize the blockchain data at the bottom of the logistics information platform to synchronize the logistics information to the third-party relational database. The experimental results show that the proposed method can improve the data entry time of the system by 5.2%, and the system occupancy rate is less than 4.1%. It is proved that the proposed model can simplify the data attributes of the Internet of Things, improve the universality of data, effectively integrate the structural characteristics of the Internet of Things and blockchain, and realize safe and efficient data management and application.
Repeated walking challenge campaign participation increases step averages among Mexican Americans living in an inactive U.S.-Mexico border community
Authors: Valenzuela Roy , Miller Mary , Salinas Jennifer J. 
Published: May 2023

AbstractMexican Americans are among the least active race/ethnic groups in the United States, most notably during leisure time. We sought to ascertain the effect of repeated participation in community-based walking challenges on average steps as a potential strategy for improving physical activity engagement in a predominately Hispanic community in far west Texas. A total of 354 participants were recruited through a community-wide walking challenge campaign. Data were analyzed at baseline and 2 weeks post-challenge participation. We used step tracker data to determine quantifiable differences by previous challenge participation. Repeated challenge participation was associated with greater baseline step averages; however, there was no dose effect for the number of previous challenges. One previous challenge participation was no different from multiple challenges. Additionally, the type of challenge increased the likelihood of repeated challenge participation. Findings from this study provide evidence that regular community-level walking challenge campaigns contribute to sustained walking among Mexican Americans at the community level.
Intimate Partner Violence, Firearm Injuries and Homicides: A Health Justice Approach to Two Intersecting Public Health Crises
Authors: Tobin-Tyler Elizabeth 
Published: May 2023

AbstractMore than half of all intimate partner homicides involve a firearm and firearms are frequently used by perpetrators of intimate partner violence (IPV) to injure and threaten victims and survivors. Recent court decisions undermine important legal restrictions on firearm possession by IPV perpetrators, thus jeopardizing the safety of victims and survivors. This article reviews the history and recent developments in the law at the intersection of IPV and firearm violence and proposes a way forward through a health justice framework.
Characterising ice slabs in firn using seismic full waveform inversion, a sensitivity study
Authors: Pearce Emma , Booth Adam D. , Rost Sebastian , Sava Paul , Konuk Tuğrul , Brisbourne Alex , Hubbard Bryn , Jones Ian 
Published: May 2023

AbstractThe density structure of firn has implications for hydrological and climate modelling, and ice-shelf stability. The structure of firn can be evaluated from depth models of seismic velocity, widely obtained with Herglotz–Wiechert inversion (HWI), an approach that considers the slowness of refracted seismic arrivals. However, HWI is strictly appropriate only for steady-state firn profiles and the inversion accuracy can be compromised where firn contains ice layers. In these cases, full waveform inversion (FWI) may yield more success than HWI. FWI extends HWI capabilities by considering the full seismic waveform and incorporates reflected arrivals. Using synthetic firn density profiles, assuming both steady- and non-steady-state accumulation, we show that FWI outperforms HWI for detecting ice slab boundaries (5–80 m thick, 5–80 m deep) and velocity anomalies within firn. FWI can detect slabs thicker than one wavelength (here, 20 m, assuming a maximum frequency of 60 Hz) but requires the starting velocity model to be accurate to ±2.5%. We recommend for field practice that the shallowest layers of velocity models are constrained with ground-truth data. Nonetheless, FWI shows advantages over established methods, and should be considered when the characterisation of firn ice slabs is the goal of the seismic survey.
Mechano-chemical regulation of complex cell shape formation: Epidermal pavement cells—A case study
Authors: van Spoordonk Ruben , Schneider René , Sampathkumar Arun 
Published: May 2023

Abstract
All plant cells are encased by walls, which provide structural support and control their morphology. How plant cells regulate the deposition of the wall to generate complex shapes is a topic of ongoing research. Scientists have identified several model systems, the epidermal pavement cells of cotyledons and leaves being an ideal platform to study the formation of complex cell shapes. These cells indeed grow alternating protrusions and indentations resulting in jigsaw puzzle cell shapes. How and why these cells adopt such shapes has shown to be a challenging problem to solve, notably because it involves the integration of molecular and mechanical regulation together with cytoskeletal dynamics and cell wall modifications. In this review, we highlight some recent progress focusing on how these processes may be integrated at the cellular level along with recent quantitative morphometric approaches.
COMPARING METHODS FOR CO2PURIFICATION OF CREMATED BONE SAMPLES
Authors: Olsen Jesper , Daróczi Tibor-Tamás , Kanstrup Marie 
Published: May 2023

ABSTRACTDuring the last two decades the radiocarbon (14C) dating of hydroxyapatite archaeological cremated bones has become standard practice. Various pretreatment procedures exist among different laboratories of which some include fixation of SO2using “Sulfix” prior to CO2reduction. Recently it was reported that the use of Sulfix may cause the resulting14C age to be too old. Here we report on the use Sulfix at the Aarhus AMS Centre. Further, we report on an experiment designed to test alternatives for the use of Sulfix as a purification agent.
Pathogens in milk of goats and their relationship with somatic cell count
Authors: Tvarožková Kristína , Tančin Vladimír , Uhrinčať Michal , Oravcová Marta , Hleba Lukáš , Gancárová Barbora , Mačuhová Lucia , Ptáček Martin , Marnet Pierre-Guy 
Published: May 2023

AbstractWe evaluated the presence of bacterial pathogens in the milk of goats and their relationship with somatic cell count (SCC) and milk composition. The study was performed on a dairy farm in northern Slovakia. Half udder milk samples were collected from goats in June and July. The samples were divided on the basis of SCC into 4 bands (SCC1 lowest to SCC4 highest). Bacterial pathogens were only detected in 13% of samples. SCC3 and SCC4 had 15 and 25% positive samples respectively compared with SCC1 (2%) and SCC2 (14%). Coagulase-negative staphylococci (CNS) were the most common isolates (73%), of which Staphylococcus caprae was the most frequently isolated (65%). In samples with ≥ 1000 × 103 cells ml− 1 (SCC3, SCC4) there was higher somatic cell score (SCS) in the presence of a pathogen (7.48 ± 0.11) than without a pathogen (7.16 ± 0.05, P < 0.01). Statistically significant but weak negative correlations were observed between SCS and lactose, dry matter and non-fat dry matter. In conclusion, a higher percentage of bacteriologically positive milk samples was observed in both SCC3 and SCC4 groups but this does not explain the aetiology of high SCC in the milk of goats that are apparently free of bacteria. As a diagnostic tool, SCC is probably less useful in goats than in cows.