bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploiting fear and vulnerabilities of senior citizens: are regulatory changes required to prevent digital frauds?
Authors: Murthy Nilaya , Gopalkrishnan Santosh 
Published: July 2023

Purpose
This paper aims to understand the emotional patterns of senior citizens when they digitally transact online and how the personality trait of neuroticism can be a vital part of being susceptible to fraud. The authors identify with the cognitive aspect of fear as a vista of neuroscience and behavioural finance in digital banking in today’s banking 5.0 where consumer centricity stands as one of the pillars of the Digital Payment Index of RBI.

Design/methodology/approach
This study is empirical and investigative in nature. Primary data has been collected through online questionnaires (via Google Forms) and the interview method to understand the phenomenology of fear and incidents related to becoming victims of fraud and its propensity.

Findings
The results exhibit that fear and emotional patterns do affect vulnerability and have a long-lasting psychological impact and susceptivity towards digital frauds.

Practical implications
Fear as an emotion is used to understand the emotional expressive patterns of senior citizens as consumers of digital banking. The OCEAN model is one of the widely used personality models at the global level. This research study helps in highlighting the nuances linked to the behavioural and cognitive part of fear in digital crime.

Originality/value
This research will be beneficial to reduce the susceptibility towards fraud from a behavioural perspective in the usage of digital banking and evaluate solutions for senior citizens to mitigate and cope up with the pressures and perils associated with digital frauds.
MOMS: A pipeline for scaffolding using multi‐optical maps
Authors: Xu Jiang , Liao Baosheng , Guo Shuai , Xiao Shuiming , Liao Xuejiao , Jiang Hongshan , Zang Chen , Shen Xiaofeng , Chu Yang , Wu Wenguang , Dou Deqiang , Luo Lu , Li Qiushi , Yang Tae‐Jin , Guo Yiming , Huang Zhihai , Chen Shilin 
Published: July 2023

AbstractHere, we report a new multi‐optical maps scaffolder (MOMS) aiming at utilizing complementary information among optical maps labelled by distinct enzymes. This pipeline was designed for data structure organization, scaffolding by path traversal, gap‐filling and molecule reuse of optical maps. Our testing showed that this pipeline has uncapped enzyme tolerance in scaffolding. This means that there are no inbuilt limits as to the number of maps generated by different enzymes that can be utilized by MOMS. For the genome assembly of the human GM12878 cell line, MOMS significantly improved the contiguity and completeness with an up to 144‐fold increase of scaffold N50 compared with initial assemblies. Benchmarking on the genomes of human and O. sativa showed that MOMS is more effective and robust compared with other optical‐map‐based scaffolders. We believe this pipeline will contribute to high‐fidelity chromosome assembly and chromosome‐level evolutionary analysis.
Psychotic‐like experiences and multimorbid psychopathology: The relationship between the 16‐item prodromal questionnaire and DSM‐IV classifications in a help‐seeking population
Authors: Palstra Eline C. , Ferwerda Janneke , van Duin Esther D. A. , Ising Helga K. , Nugter M. Annet , Smit Filip , van der Gaag Mark , van den Berg David 
Published: July 2023

AbstractAimIdentifying multimorbid psychopathology is necessary to offer more adequate treatment and ultimately reduce the prevalence of persistent mental illnesses. Psychotic symptoms are increasingly seen as a transdiagnostic indicator of multimorbidity, severity and complexity of non‐psychotic psychopathology. This study aims to investigate whether psychotic‐like experiences and subclinical psychotic symptoms as measured by the 16‐item Prodromal Questionnaire are also associated with multimorbid psychopathology.MethodsParticipants were help‐seeking individuals from outpatient mental healthcare settings and intensive home‐treatment teams, aged 17–35. Assessment included the 16‐item Prodromal Questionnaire to measure psychotic‐like experiences, the Structured Clinical Interview for DSM‐IV Axis I, and three sections of the Structured Clinical Interview for DSM‐IV Axis II Disorders to determine DSM‐IV‐TR classifications. The final sample comprised of 160 participants who scored above a cutoff of 6 items on the 16‐item Prodromal Questionnaire (HIGH‐score) and 60 participants who scored below cutoff (LOW‐score). A Poisson Regression was executed to determine the association between the PQ‐16 and DSM‐IV‐TR classifications.ResultsThe HIGH‐score group had a mean of 2.76 multimorbid disorders (range 0–7), while the LOW‐score group had a mean of 1.45 disorders (range 0–3). Participants with four to seven disorders scored high on the 16‐item Prodromal Questionnaire.ConclusionsOur results suggest that psychotic‐like experiences are associated with multimorbidity and severity of psychopathology. Screening for psychotic‐like experiences via the PQ‐16 in a help‐seeking population may help prevent under‐diagnosis and under‐treatment of comorbid psychopathology.
Demographics and outcomes of hemoglobin genotype in hospitalized patients with COVID‐19 and sickle cell disease in the United States
Authors: Ilerhunmwuwa Nosakhare Paul , Inyang Lawrence , Wasifuddin Mustafa , Aiwuyo Henry , Tahir Muhammad , Hakobyan Narek , Ankah Paul , Torere Beatrice E. , Amaechi Uchenna M. , Rayapureddy Aditya Keerthi , Wang Jen Chin 
Published: July 2023

AbstractIntroductionCoronavirus disease 2019 (COVID‐19) is associated with poor outcomes in sickle cell disease (SCD) patients. However, there is a paucity of data comparing hemoglobin (Hb) genotypes in SCD and infection outcomes.MethodsThe National Inpatient Sample was used to identify the record of hospitalizations with COVID‐19 and SCD in 2020 using the International Classification of Disease, Tenth Revision codes. Study outcomes (invasive mechanical ventilation, extracorporeal membrane oxygenation, shock, vasopressor use, measures of resource utilization, and in‐hospital mortality) were compared between hemoglobin SS, SC, and S‐beta thalassemia (Sβ).ResultsOf the 102 975 COVID‐19 hospitalizations with SCD, 87.26% had HbSS, 7.16% had HbSC, and 5.58% had HbSβ. Younger patients were more likely to have HbSS, while older patients were likely to have HbSC and HbSβ. HbSS was more frequent with Blacks, while HbSβ was more prevalent with Whites and Hispanics. Though measures of resource utilization were higher in HbSS, there was no significant difference in in‐hospital outcomes between the three genotypes.ConclusionThere is no difference in COVID‐19 outcomes among Hb genotypes in SCD. Further studies are needed to explore the reasons for this observation.
Effectiveness and safety of secukinumab in Chinese patients with moderate to severe plaque psoriasis in real‐world practice
Authors: Zhou Jian , Yuan Yuan , Liu Yanhua , Chu Mengyang , Liu Huan , Liu Qian , Wang Rui , Shao Shuai , Wang Gang , Yu Chen 
Published: July 2023

AbstractA number of randomized controlled trials and real‐world studies have demonstrated the effectiveness and safety of secukinumab in the treatment of moderate to severe psoriasis, whereas data on a large cohort of Chinese patients in long‐term real‐world practice are limited. This was a single‐centre, uncontrolled, single‐arm, prospective, observational cohort study that included 254 psoriatic patients treated with secukinumab between September 2019 and December 2022. Demographic and clinical characteristics of patients, clinical response and adverse events were evaluated. The 75% improvement in Psoriasis Area and Severity Index score (PASI 75), PASI 90, and PASI 100 in the 300 mg secukinumab group at 12 weeks were 91.7%, 74.0% and 39.7% respectively, increasing to 94.5%, 74.5% and 47.6% at 52 weeks. High body mass index (BMI), previous exposure to biologic therapies and history of previous conventional systemic therapies were associated with lower rates of PASI response. During the study period, 68 patients reported 83 adverse events (AEs) and the most frequent AEs were eczematous lesions. Up to 14.5% patients withdrew treatment due to disease remission combined with inconvenient transportation during the COVID‐19 pandemic at 52 weeks. The rate of psoriasis exacerbation after COVID‐19 infection in patients treated with secukinumab was 24.3% (17/70). This real‐world study confirmed the high effectiveness of secukinumab in Chinese patients with moderate to severe plaque psoriasis, with an acceptable safety profile.
English learning and use in Hong Kong's bilingual education: Implications for L2 learners’ development of interactional competence
Authors: Chan Jim Yee Him , Walsh Steve 
Published: July 2023

AbstractThe use of English in international communication has focused scholarly attention on L2 learners’ development of interactional competence (IC), that is, the ability to co‐construct interactions purposefully and meaningfully in specific contexts. Under Hong Kong's bilingual education policy, students mainly learn and speak English in two classroom contexts: (1) English language and (2) English‐medium‐instruction (EMI) content‐area subject lessons, which may contribute to their IC development. This study compared the English‐speaking/learning experiences of students in these two classroom settings in three Hong Kong secondary schools. Task‐based language teaching (TBLT) was the recommended teaching approach in the English language subject in all these schools, but they adopted different medium‐of‐instruction arrangements in content‐area subjects. Their students also had different academic attainments. The investigation adopted a case study approach consisting of a questionnaire and semi‐structured focus group interviews (N = 160). Our findings suggest that students generally lacked opportunities to speak English, regardless of the specific school‐based policies. The higher‐proficiency students were given more opportunities to speak English in group/pair activities both in English language and EMI content‐area subjects. In contrast, the lower‐proficiency students received more explicit teaching of the linguistic forms/structures required in English examinations. The paper concludes by highlighting several critical issues concerning students’ IC development in bilingual education, namely, the effects of English‐medium education on students’ speaking ability, implementation of TBLT, the influence of examinations on teaching practices, and teachers’ role in promoting students’ interactional competence through classroom interactions.
Association of depression with hypertensive left ventricular hypertrophy in age, sex, and education level‐specific differences
Authors: Shi Shuang , Guan Gongchang , Wang Junkui , Hui Rutai , Zhang Yong , Cui Qianwei , Zhao Jingsha , Zhu Ling 
Published: July 2023

AbstractPrevious studies have shown that hypertension and depression are associated with worse cardiovascular outcomes and reduced quality of life. Left ventricular hypertrophy (LVH) is strongly linked to increased mortality and cardiovascular disease, and depression may be one of the key factors contributing to hypertensive LVH. The authors consecutively enrolled 353 patients with uncomplicated hypertension between November 2017 and May 2021. All participants completed the Hamilton Depression Scale (HAM‐D) to assess their depression status, with depression defined as a HAM‐D score of 20 or higher. Linear regression analysis revealed a positive association between HAM‐D and LVMI (adjusted β, 1.51, 95% CI, 1.19–1.83, p < .001). Logistic regression models showed that individuals with hypertension and depression had a higher risk of LVH than those with hypertension alone (adjusted OR, 2.51, 95% CI, 1.14–5.52, p = .022). The association between depression and LVH significantly interacted with age, sex, education levels, but not BMI and household income. Following age, sex, and education levels stratification, an independent association of depression and LVH was observed only in age <60 years (age <60 years: OR, 7.36, 95% CI, 2.25–24.13, p < .001), male (male: OR, 16.16, 95% CI, 3.80–68.73, p < .001), and higher education levels (high school and above: OR, 11.09, 95% CI, 2.91–42.22, p < .001). Our findings suggest that depression is a significant risk factor for LVH in hypertensive patients, particularly in those who are under 60 years of age, male, and have higher education levels.
Correlation between serum pro‐inflammatory cytokine levels and the prognosis of the patients with acute liver failure
Authors: Murakami Serami , Uchida Takuro , Imamura Michio , Suehiro Yosuke , Namba Maiko , Fujii Yasutoshi , Uchikawa Shinsuke , Teraoka Yuji , Fujino Hatsue , Ono Atsushi , Nakahara Takashi , Murakami Eisuke , Okamoto Wataru , Yamauchi Masami , Kawaoka Tomokazu , Miki Daiki , Hayes C Nelson , Tsuge Masataka , Ohira Masahiro , Ohdan Hideki , Oka Shiro 
Published: July 2023

AbstractBackground and AimThe prognosis of acute liver failure (ALF) remains poor, and liver transplantation is an alternative treatment option. Assessing the prognosis of ALF is important in determining treatment strategies. Here, we investigated clinical factors including serum pro‐inflammatory cytokine levels that are associated with the prognosis of ALF.MethodsSixty‐six patients who developed ALF were enrolled in this study. Serum concentrations of 12 pro‐inflammatory cytokines were measured on admission. The prognosis and factors associated with survival and development of hepatic coma were analyzed.ResultsOf 66 patients, 4 patients underwent liver transplantation, and 49 patients were rescued without liver transplantation, while the remaining 13 patients died. Serum concentrations of interleukin (IL)‐1β, IL‐4, IL‐6, IL‐8, IL‐13, TNF, IFN ‐γ, IP‐10, and G‐CSF were significantly elevated in ALF patients. IL‐4 and IL‐8 levels were higher in patients who underwent liver transplantation or died than in rescued patients. Multivariable analysis identified age ≥ 55 years and IL‐4 ≥ 1.2 pg/mL on admission as independent factors for mortality. Serum IL‐8 levels were higher in patients with hepatic coma, and prothrombin‐international normalized ratio ≥ 3.5 and IL‐8 ≥ 77.2 pg/mL on admission were associated with development of hepatic coma after admission.ConclusionSerum levels of several pro‐inflammatory cytokines were elevated in ALF patients. IL‐4 and IL‐8 were correlated with survival and development of hepatic coma after admission, respectively. Measurement of serum pro‐inflammatory cytokines seems to be useful for the management of ALF.
Role of ferroptosis in periodontitis: An animal study in rats
Authors: Fu Earl , Kuo Chan‐Yen , Hsia Yi‐Jan , Huang Yiao‐Mien , Tseng Hui‐Hwa , Fu Min‐Wen , Shih Kuang‐Chung 
Published: July 2023

AbstractObjectiveThis study aimed to investigate (1) the temporal pattern of ferroptosis, an iron‐dependent cell death, in ligation‐induced rat periodontitis and (2) the effect of ferrostatin‐1, a ferroptosis inhibitor, on the model.BackgroundFerroptosis may contribute to various diseases. However, the role of ferroptosis in periodontitis is still fully understood.MethodsIn the first experiment, 25 rats with ligation‐induced periodontitis were sacrificed on days 0, 1, 2, 7, and 10. Gingivae were obtained to determine tumor necrosis factor (TNF)‐α, interleukin (IL)‐1β, and ferroptotic biomarkers, including solute carrier family 3 member 2 (SLC3A2) and solute carrier family 7 member 11 (SLC7A11) and glutathione peroxidase 4 (Gpx4), via immunoblotting. Using microcomputed tomography (μCT) and histology, the periodontal soft and hard tissue lesions, including dental alveolar bone crest level, bony characteristics of the surrounding alveolus, periodontal tissue inflammation, and periodontal tissue losses, were evaluated. In study two, 16 rats with induced periodontitis were grouped according to ferrostatin‐1 treatment. The rats were intraperitoneally injected with solvent or ferrostatin‐1 (1.5 mg/kg/day) 1 day before ligation and sacrificed on days 7 and 10. Gingival protein changes and periodontal tissue damage were also examined.ResultsIn study one, SLC3A2/SLC7A11 and Gpx4 decreased since day 1; however, TNF‐α/IL‐1β increased on days 7 and 10. Moreover, the μCT/histology revealed resorptive bony characteristics, inflamed gingival tissue, and periodontal attachment loss. In study two, ferrostatin‐1‐injected rats exhibited significantly increased SLC3A2/SLC7A11 and Gpx4 but decreased TNF‐α/IL‐1β than vehicle rats. They also revealed lessened bone resorption, tissue inflammation, and attachment loss.ConclusionThis study highlights the role of ferroptosis, via the system Xc/Gpx4 pathway, in experimental periodontitis and may serve as a regulatory strategy.
The two‐component system CroRS acts as a master regulator of cell envelope homeostasis to confer antimicrobial tolerance in the bacterial pathogen Enterococcus faecalis
Authors: Todd Rose Francesca O. , Darnell Rachel L. , Morris Sali M. , Rose Olivia E. , Paxie Olivia , Campbell Georgia , Cook Gregory M. , Gebhard Susanne 
Published: July 2023

AbstractAntimicrobial tolerance is the ability of a microbial population to survive, but not proliferate, during antimicrobial exposure. Significantly, it has been shown to precede the development of bona fide antimicrobial resistance. We have previously identified the two‐component system CroRS as a critical regulator of tolerance to antimicrobials like teixobactin in the bacterial pathogen Enterococcus faecalis. To understand the molecular mechanism of this tolerance, we have carried out RNA‐seq analyses in the E. faecalis wild‐type and isogenic croRS mutant to determine the teixobactin‐induced CroRS regulon. We identified a 132 gene CroRS regulon and demonstrate that CroRS upregulates biosynthesis of all major components of the enterococcal cell envelope in response to teixobactin. This suggests a coordinating role of this regulatory system in maintaining integrity of the multiple layers of the enterococcal envelope during antimicrobial stress, likely contributing to bacterial survival. Using experimental evolution, we observed that truncation of HppS, a key enzyme in the synthesis of the quinone electron carrier demethylmenaquinone, was sufficient to rescue tolerance in the croRS deletion strain. This highlights a key role for isoprenoid biosynthesis in antimicrobial tolerance in E. faecalis. Here, we propose a model of CroRS acting as a master regulator of cell envelope biogenesis and a gate‐keeper between isoprenoid biosynthesis and respiration to ensure tolerance against antimicrobial challenge.
Spatial Contexts of Language Shift and Heritage Language Retention within a Highly Diverse Population: Sydney, Australia
Authors: Forrest James 
Published: July 2023

AbstractIn immigrant countries like America, Canada and Australia, heritage language retention and language shift (to the language of the receiving society) have long been associated with classical spatial theory, of initial segregation into inner city ethnic enclaves and subsequent intra‐urban migration into majority ‘white’ or ‘mainstream’ residential suburbia, respectively. First through third generation spatial dynamics of shift and retention in Sydney are analysed for the ten largest post‐1945 labour workforce immigrant streams from Europe and the ten post‐1960s mainly skilled immigrant streams from the Middle East and Asia. Quartile and diversity analyses show that the association of intergenerational heritage language retention with spatial concentration and language shift with spatial dispersion has been superceded by a new set of spatial dynamics. Instead, patterns of retention and shift are responding to high levels of population diversity and minority majority suburbs where culturally hegemonic mainstream and minority cultural groups are intermixed across 80 per cent of Sydney's suburbs.
Complete genome sequence of a novel species of
Brevundimonas
(strain NIBR10)
Authors: Min Myeong-Hyeon , Jung Dong-Hyun , Kim Jin Nam , Yu Jaewoong , Choi Ahhyeon 
Published: July 2023

ABSTRACT

The complete genome sequence of strain NIBR10 was sequenced using PacBio RS II (Pacific Biosciences) sequencing platform. The 4,006,378-bp genome has a G + C content of 66.89% and around 3,832 coding sequences. Genomic data will provide valuable research for natural taxonomy and comparative genomics of the genus
Brevundimonas
.
Pre-pandemic mental health and coping strategy usage during the COVID-19 pandemic: a cross-sectional analysis of the Southern Cities Study
Authors: Cho Gawon , Hagen Daniel , Goldmann Emily 
Published: July 2023

Abstract
Background
Little is known about the usage of coping strategies recommended by the World Health Organization and the Centers for Disease Control and Prevention during the COVID-19 pandemic and whether coping strategy usage varies by pre-pandemic mental health. This study examined the prevalence of different coping strategies and associations of their usage with pre-pandemic mental health.

Methods
Data were collected from adults residing in metropolitan areas of the U.S. South in May/June 2020 using random-digit-dialing and web-based surveys (n = 1,644). We estimated the prevalence of each coping strategy: (1) keeping up-to-date about COVID-19; (2) taking breaks from the news or social media; (3) taking care of physical health; (4) engaging in relaxing activities; (5) reaching out to and spending time with others; and (6) trying to find comfort in religious or spiritual beliefs. We examined the association between the use of each strategy and pre-pandemic mental health using modified Poisson regression, adjusting for covariates. We also analyzed the association between pre-pandemic mental health and the number of coping strategies employed using ordered logistic regression.

Results
The most prevalent strategies were: “keeping up-to-date about COVID-19” (53%), “taking care of physical health” (52%), and “reaching out to and spending time with others” (52%). Good pre-pandemic mental health was associated with an increased prevalence of “reaching out to and spending time with others” (adjusted prevalence ratio, 1.43; 95% confidence interval, 1.07–1.91). The use of other coping strategies and the number of coping strategies used during the pandemic did not vary by pre-pandemic mental health.

Conclusions
Our findings suggest that people who had good pre-pandemic mental health were more likely to connect with other people during the COVID-19 pandemic. Given the well-documented impact of social support on mental health in disaster contexts, efforts to promote safe social connections for those with pre-existing mental health concerns are needed.