bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thin film-based colorful radiative cooler using diffuse reflection for color display
Authors: Wen Junren , Chen Xiao , Zhu Zeyu , Zhu Yining , Luo Hao , Wang Yusi , Liu Yujie , Wang Hailan , Yuan Wenjia , Zhang Yueguang , Yang Chenying , Shen Weidong 
Published: August 2023

AbstractColorful radiative coolers (CRCs) can be widely applied for energy sustainability especially and meet aesthetic purposes simultaneously. Here, we propose a high-efficiency CRC based on thin film stacks and engineered diffuse reflection unit, which brings out 7.1 °C temperature difference compared with ambient under ~ 700 W·m−2 solar irradiation. Different from analogous schemes, the proposed CRCs produce vivid colors by diffuse reflection and rest of the incident light is specular-reflected without being absorbed. Adopting the structure of TiO2/SiO2 multilayer stack, the nanophotonic radiative cooler shows extra low absorption across the solar radiation waveband. Significant radiative cooling performance can be achieved with the emissivity reaching 95.6% in the atmosphere transparent window (8–13 μm). Moreover, such CRC can be fabricated on flexible substrates, facilitating various applications such as the thermal management of cars or wearables. In conclusion, this work demonstrates a new approach for color display with negligible solar radiation absorption and paves the way for prominent radiative cooling.
A cognitive–behavioural therapy programme for managing depression and anxiety in long-term physical health conditions: mixed-methods real-world evaluation of the COMPASS programme
Authors: Seaton Natasha , Moss-Morris Rona , Hulme Katrin , Macaulay Hannah , Hudson Joanna 
Published: August 2023

Background
Mental health comorbidities are common in physical long-term health conditions.

Aims
We evaluate the effectiveness of COMPASS, a therapist-supported, digital cognitive–behavioural therapy programme specifically designed to treat anxiety/depression in the context of long-term conditions. We also investigate patient experiences of the programme.

Method
We utilised a mixed-methods, non-randomised design. We analysed pre–post data from 76 patients with long-term conditions who were receiving psychological treatment (COMPASS) via local NHS services, using paired sample t-tests and Cohen's d, with depression, anxiety, distress and functional impairment self-report scales. Qualitative interviews explored patients’ experiences of using COMPASS. Twenty-one semi-structured interviews were completed and underwent inductive thematic analysis.

Results
Patients who received COMPASS had significantly reduced depression (−2.47, 95% CI −3.7 to −1.3, P < 0.001; Cohen's d = −0.376), anxiety (−2.30, 95% CI −3.6 to −1.2, P < 0.001; Cohen's d = −0.420) and psychological distress (−4.87, 95% CI −7.0 to −2.7, P < 0.001; Cohen's d = −0.422) and significantly improved functional impairment (−3.00, 95% CI −4.8 to −1.2, P ≤ 0.001; Cohen's d = −0.282). Effect sizes were larger when analyses included only patients with clinically significant baseline symptoms: depression (−4.02, 95% CI −5.6 to −2.5, P < 0.001; Cohen's d = −0.701), anxiety (−3.60, 95% CI −5.3 to −1.9, P < 0.001; Cohen's d = −0.739), psychological distress (−5.58, 95% CI −7.9 to −3.2, P < 0.001; Cohen's d = −0.523), functional impairment (−3.28, 95% CI −5.4 to −1.1, P ≤ 0.001; Cohen's d = −0.355). Qualitative analysis yielded two meta-themes: engagement and integration of mental and physical health.

Conclusions
Results suggest that COMPASS is effective in NHS settings, and is acceptable to patients. Content tailored to long-term conditions, therapist support and clear delivery strategies should be prioritised to aid intervention implementation.
A scoping review of social media in child, adolescents and young adults: research findings in depression, anxiety and other clinical challenges
Authors: Hilty Donald M. , Stubbe Dorothy , McKean Alastair J. , Hoffman Pamela E. , Zalpuri Isheeta , Myint Myo T. , Joshi Shashank V. , Pakyurek Murat , Li Su-Ting T. 
Published: August 2023

BackgroundSocial media and other technologies are reshaping communication and health.AimsThis review addresses the relationship between social media use, behavioural health conditions and psychological well-being for youth aged <25 years.MethodA scoping review of 11 literature databases from 2000 to 2020 explored research studies in youth in five areas: clinical depression and anxiety, quantitative use, social media mode, engagement and qualitative dimensions and health and well-being.ResultsOut of 2820 potential literature references, 140 met the inclusion criteria. The foci were clinical depression and anxiety disorders (n= 78), clinical challenges (e.g. suicidal ideation, cyberbullying) (n= 34) and psychological well-being (n= 28). Most studies focused on Facebook, Twitter, Instagram and YouTube. Few studies are longitudinal in design (n= 26), had comparison groups (n= 27), were randomised controlled trials (n= 3) or used structured assessments (n= 4). Few focused on different youth and sociodemographic populations, particularly for low-income, equity-seeking and deserving populations. Studies examined association (n= 120; 85.7%), mediating (n= 16; 11.4%) and causal (n= 4; 2.9%) relationships. Prospective, longitudinal studies of depression and anxiety appear to indicate that shorter use (≤3 h/day) and purposeful engagement is associated with better mood and psychological well-being. Depression may predict social media use and reduce perception of support. Findings provide families, teachers and providers ways to engage youth.ConclusionsResearch opportunities include clinical outcomes from functional perspective on a health continuum, diverse youth and sociodemographic populations, methodology, intervention and privacy issues. More longitudinal studies, comparison designs and effectiveness approaches are also needed. Health systems face clinical, training and professional development challenges.
Acute Statin Withdrawal Does not Interfere With the Improvements of a Session of Exercise in Postprandial Metabolism
Authors: Alvarez-Jimenez Laura , Morales-Palomo Felix , Moreno-Cabañas Alfonso , Ortega Juan F , Mora-Gonzalez Diego , Mora-Rodriguez Ricardo 
Published: August 2023

Abstract

Background
The risk for atherogenic plaque formation is high after ingestion of meals in individuals with high blood lipid levels (ie, dyslipidemia). Statins and exercise reduce the rise of blood triglyceride concentrations after a meal, but the effect of their combination is unclear.

Methods
In a randomized crossover design, 11 individuals with dyslipidemia and metabolic syndrome treated with statins underwent a mixed-meal (970 ± 111 kcal, 24% fat, and 34% carbohydrate) tolerance test. Plasma lipid concentrations, fat oxidation, glucose, and glycerol kinetics were monitored immediately prior and during the meal test. Trials were conducted with participants under their habitual statin treatment and 96 hours after blinded statin withdrawal. Trials were duplicated after a prolonged bout of low-intensity exercise (75 minutes at 53 ± 4% maximal oxygen consumption) to study the interactions between exercise and statins.

Results
Statins reduced postprandial plasma triglycerides from 3.03 ± 0.85 to 2.52 ± 0.86 mmol·L−1 (17%; P = .015) and plasma glycerol concentrations (ie, surrogate of whole-body lipolysis) without reducing plasma free fatty acid concentration or fat oxidation. Prior exercise increased postprandial plasma glycerol levels (P = .029) and fat oxidation rates (P = .024). Exercise decreased postprandial plasma insulin levels (241 ± 116 vs 301 ± 172 ρmol·L−1; P = .026) but not enough to increase insulin sensitivity (P = .614). Neither statins nor exercise affected plasma glucose appearance rates from exogenous or endogenous sources.

Conclusions
In dyslipidemic individuals, statins reduce blood triglyceride concentrations after a meal, but without limiting fat oxidation. Statins do not interfere with exercise lowering the postprandial insulin that likely promotes fat oxidation. Last, statins do not restrict the rates of plasma incorporation or oxidation of the ingested glucose.
When Men Get No Share
Authors: Kooria Mahmood 
Published: August 2023

AbstractIn matrilineal societies, women had more status, power, and property than men. Most scholars of Islam believed that matrilineal cultures were against the ethos of the religion, which is patrilineal, patrilocal, and patriarchal. But millions of Muslims across the Indian Ocean littoral have been following matriliny for several centuries. It was also one of the most convenient ways to engage in Indian Ocean trade: men could voyage as merchants, sailors, and itinerants, while women stayed on land with the property and controlled households and wider social spheres. This economic and social stability gave women an upper hand in economic and personal choices, and within marriages, they could and did move about freely. The matrilineal system not only connected maritime Muslims but also raised serious questions about the Islamic jurisprudential tradition that evolved in the Middle East through its peculiar practices of ownership of property, kinship, and marital norms. From the late eighteenth century onward, the system has been subjected to significant internal and external criticisms. These especially targeted inheritance-related customs where men got no share in the property. With a special focus on debates over inheritance laws, this article explores the transregional and transtemporal ways in which matrilineal Muslims defended the system within Islamic legal epistemologies and maritime social systems.
Anaphylaxis caused by taking pantoprazole: case series
Authors: Telaku Skender , Veliu Arber , Zenelaj Qendrim , Telaku Mimoza , Fejza Hajrullah , Alidema Fitim 
Published: August 2023

Introduction: Pantoprazole is one of the most widely used proton pump inhibitors, but anaphylaxis occurs rarely during its use. The purpose of reporting these two cases is to show that pantoprazole is not a drug without problems; it can also cause anaphylactic reactions. Cases description: A 42-year-old woman presented to the emergency department due to dyspeptic complaints. Immediately at the end of the infusion of pantoprazole, there started to be numbness of the tongue, itching all over the body, and difficulty in breathing. Half an hour after taking a pantoprazole 40 mg capsule, a 58-year-old woman started to experience redness of the face, thickening of the tongue, itching, bloating, and dizziness. Arterial pressure was 80/60 mmHg, pulse 150/minute, while saturation had dropped to 88%. In both cases, fluids, adrenaline, antihistamines, methylprednisolone, and calcium were immediately started. After the improvement of their general conditions, both patients were discharged home. Discussion: The first case relates to anaphylaxis after the intravenous administration of pantoprazole, and the second case relates to the appearance of anaphylaxis after its oral administration. Conclusion: Health workers need to be informed about the possibility of anaphylaxis in patients taking both oral and parenteral pantoprazole.
HIV pre-exposure prophylaxis and incidence of sexually transmitted infections in Brazil, 2018 to 2022: An ecological study of PrEP administration, syphilis, and socioeconomic indicators
Authors: Mendonça Gil Paula Knoch , Conrado Danilo dos Santos , Nascimento Ana Isabel do , Azevedo Micael Viana de , Cunha João Cesar Pereira da , Koch Gabriel Serrano Ramires , Maciel Camila Guadeluppe , Ribeiro Alisson André , Paranhos Filho Antonio Conceição , Medeiros Márcio José de , Santos-Pinto Cláudia Du Bocage , Falcão de Oliveira Everton 
Published: August 2023

Background
Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is one of the pillars of a combination prevention strategy for reducing the risk of new infections caused by HIV. The daily use of antiretroviral drugs by individuals who are not infected with HIV is required to prevent infection. Although its efficacy has been well established in the literature, in recent years, the decreased supply of antiretroviral drugs has been associated with an increase in the incidence of sexually transmitted infections (STI) and changes in the social determinants of health. An ecological study was conducted covering a five-year period (2018–2022), starting from the year of initiation of PrEP administration in Brazilian state capitals.

Principal findings
Descriptive analysis was performed, and the spatial distribution of study data was taken into account. Correlation analysis was used to assess the association between PrEP administration, the incidence and detection rate of STI, and socioeconomic data. The southern region showed the highest incidence rates of STI, but the northern and northeastern regions demonstrated the worst socioeconomic indicators, especially those related to illiteracy and basic sanitation. PrEP administration was significantly correlated with illiteracy (ρ = -0.658), per capita income (ρ = 0.622), public garbage collection (ρ = 0.612), syphilis (ρ = 0.628) and viral hepatitis (ρ = 0.419) incidences. Further, all STI were significantly associated with illiteracy and per capita income.

Significance
Our findings highlight the need to continue exploring PrEP use and rising syphilis rates. In terms of policy, PrEP administration appears to be inversely associated with regions of greater social vulnerability. Further efforts should focus on the social determinants and health needs of this population to improve access to PrEP and reduce social disparities.
Impact of vericiguat on baroreflex-mediated sympathetic circulatory regulation: An open-loop analysis
Authors: Yokoi Aimi , Kawada Toru , Yokota Shohei , Kakuuchi Midori , Matsushita Hiroki , Nishiura Akitsugu , Li Meihua , Uemura Kazunori , Alexander Joe , Tanaka Ryou , Saku Keita 
Published: August 2023

Aims
To quantify in vivo the effects of the soluble guanylate cyclase (sGC) stimulator, vericiguat, on autonomic cardiovascular regulation in comparison with the nitric oxide (NO) donor, sodium nitroprusside.

Methods
In anesthetized Wistar–Kyoto rats, baroreflex-mediated changes in sympathetic nerve activity (SNA), arterial pressure (AP), central venous pressure (CVP), and aortic flow (AoF) were examined before and during the intravenous continuous administration (10 μg·kg−1·min−1) of vericiguat or sodium nitroprusside (n = 8 each). Systemic vascular resistance (SVR) was calculated as SVR = (AP–CVP) / AoF.

Results
Neither vericiguat nor sodium nitroprusside affected fitted parameters of the baroreflex-mediated SNA response. Both vericiguat and sodium nitroprusside decreased the AP mainly through their peripheral effects. Vericiguat halved the slope of the SNA–SVR relationship from 0.012 ± 0.002 to 0.006 ± 0.002 mmHg·min·mL−1·%−1 (P = 0.008), whereas sodium nitroprusside caused a near parallel downward shift in the SNA–SVR relationship with a reduction of the SVR intercept from 1.235 ± 0.187 to 0.851 ± 0.123 mmHg·min/mL (P = 0.008).

Conclusion
Neither vericiguat nor sodium nitroprusside significantly affected the baroreflex-mediated SNA response. The vasodilative effect of vericiguat became greater toward high levels of SNA and AP, possibly reflecting the increased sGC sensitivity to endogenous NO. By contrast, the effect of sodium nitroprusside was more uniform over the range of SNA. These results help better understand cardiovascular effects of vericiguat.
Post-COVID care delivery: The experience from an Irish tertiary centre’s post-COVID clinic
Authors: Heeney Aoife , Connolly Stephen P. , Dillon Rachel , O’Donnell Aisling , McSweeney Tara , O’Kelly Brendan , Cotter Aoife G. , Sheehan Gerard , Lambert John S. , Muldoon Eavan G. , McGinty Tara 
Published: August 2023

Background
The long-term effects of SARS-CoV-2 infection and optimal follow-up approach are not well-recognised. Here we describe the implementation of a post-COVID clinic in an Irish tertiary centre after the first wave of the pandemic. This study describes the characteristics of our patient cohort and the operations and outcomes of the clinic, exploring some of the risk factors for developing post-COVID syndrome and the appropriateness of the triage system employed.

Methods
All SARS-CoV-2 positive patients from March 10th to June 14th 2020 were telephone-triaged as red, amber or green based on ongoing symptoms with clinic appointments scheduled accordingly. All clinic visits were face-to-face with the infectious diseases medical team and a proforma for each patient was completed. Data were collected retrospectively by reviewing the proformas and the electronic medical record (EMR).

Results
311 patients attended the clinic. Median time from illness to clinic appointment was 95 days (IQR 77–105.5). 204 patients (66%) were female, 192 (62%) were hospital staff, and the median age was 43 years (IQR 31–53). 138 patients (44%) had required hospital admission. At their first clinic visit 219 patients (70%) had ongoing symptoms. A further appointment was made for 62 patients (20%). 34 patients (11%) were discussed at an MDT meeting, and 55 (18%) were referred onward to a specialist service. 85% of those triaged green, 73% of those triaged amber, and 39% of those triaged red did not receive further follow up after one clinic visit. Patients were more likely to require follow up with reported dyspnoea (OR 5.6; 95% CI 2.8–11.3; p <0.001), cough (OR 3.0; 95% CI 1.1–8.4, p = 0.04), and palpitations (OR 3.6; 95% CI 1.0–12.3; p = 0.04). Female sex was associated with increased odds of a higher triage category (OR 1.8; 95% CI 1.08 to 3.20; p = 0.02), as was requiring admission to hospital (OR 4.0; 95% CI 2.34 to 6.90; p < 0.001).

Conclusion
The long-term effects of COVID-19 are significant with 70% of our cohort experiencing persistent symptoms. Persistent dyspnoea, cough and palpitations were associated with increased need for follow up. This study also suggests that a traffic light telephone-triage service followed by a face-to-face medical-led clinic could be an effective way of identifying patients who require further management.
Evaluation of a large-scale health department naloxone distribution program: Per capita naloxone distribution and overdose morality
Authors: Freiermuth Caroline E. , Ancona Rachel M. , Brown Jennifer L. , Punches Brittany E. , Ryan Shawn A. , Ingram Tim , Lyons Michael S. 
Published: August 2023

Objectives
To report per-capita distribution of take-home naloxone to lay bystanders and evaluate changes in opioid overdose mortality in the county over time.

Methods
Hamilton County Public Health in southwestern Ohio led the program from Oct 2017-Dec 2019. Analyses included all cartons distributed within Hamilton County or in surrounding counties to people who reported a home address within Hamilton County. Per capita distribution was estimated using publicly available census data. Opioid overdose mortality was compared between the period before (Oct 2015-Sep 2017) and during (Oct 2017-Sep 2019) the program.

Results
A total of 10,416 cartons were included for analyses, with a total per capita distribution of 1,275 cartons per 100,000 county residents (average annual rate of 588/100,000). Median monthly opioid overdose mortality in the two years before (28 persons, 95% CI 25–31) and during (26, 95% CI 23–28) the program did not differ significantly.

Conclusions
Massive and rapid naloxone distribution to lay bystanders is feasible. Even large-scale take-home naloxone distribution may not substantially reduce opioid overdose mortality rates.
The association between maternal body mass index and serial plasma oxytocin levels during labor
Authors: Ramö Isgren Anna , Carlhäll Sara , Dennis Retrato Mark , Kodikara Chamali , A. Ubhayasekera Kumari , Kjölhede Preben , Bergquist Jonas , Blomberg Marie 
Published: August 2023

Objective
To evaluate the association between maternal body mass index (BMI) and plasma oxytocin (OT) levels at different OT infusion rates in labor.

Methods
A prospective observational study analyzing serial plasma samples in laboring women with OT infusion. The women were categorized into three groups, women with non-obesity (BMI 18.5–29.9, n = 12), obesity (BMI 30.0–34.9, n = 13), and morbid obesity (BMI ≥ 35.0, n = 15). Plasma OT was analyzed using tandem mass spectrometry.

Results
Except for a low positive correlation between OT levels and BMI and significantly increased plasma OT levels in women with morbid obesity at the OT infusion rate of 3.3 mU/min, no significant differences in OT levels between the BMI groups were found. Further, the inter-individual differences in OT levels were large and no dose-dependent increase of OT levels was seen.

Conclusions
Other factors than plasma OT levels may be more likely to determine the clinical response of OT infusion in women with obesity. Perhaps the observed clinical need and individual response would be a better predictor of plasma OT levels than a pre-determined OT infusion rate. The OT dosage guidelines for labor augmentation should be individualized according to clinical response rather than generalized.

Trial registration
Clinical trial registration: ClinicalTrials.gov ID NCT04093479.
Cardiopulmonary resuscitation in veno-venous-ECMO patients—A retrospective study on incidence, causes and outcome
Authors: Booke Hendrik , Zacharowski Kai , Adam Elisabeth Hannah , Raimann Florian Jürgen , Bauer Frederike , Flinspach Armin Niklas 
Published: August 2023

Introduction
Cardiac arrest in a modern intensive care unit (ICU) is associated with poor outcome although optimal resources are present at all times. Data on cardiac arrest (CA) of the increasing cohort of patients with veno-venous-extracorporeal membrane oxygenation (VV-ECMO) are not available. Due to the highly invasive nature of this procedure, other incidences and causes of cardiac arrest are expected when compared to the ICU population without ECMO. This study focuses on cardiac arrest under VV-ECMO treatment.

Methods
Retrospective single-center observational study including all VV-ECMO patients from 1st January 2019 until 31st March 2022. Primary focus of this study was number and causes for CA during VV-ECMO treatment. Secondary endpoints were treatment procedure, complications and outcome.

Results
140 patients were treated with VV-ECMO in the study period. Of those, 23 patients had 29 CA with need for cardiopulmonary resuscitation (CPR) during VV-ECMO treatment. Nearly half of all CA (48%; n = 14) occurred during medical procedures and 21% (n = 6) were device related. Pulseless electric activity (PEA) was the most common rhythm upon CPR initiation (72%). ROSC was achieved in 86%, two CA (6.9%) resulted in extracorporeal CPR. Survival to hospital discharge was 13% following CPR.

Conclusion
CA occurs in over 15% of all patients treated with a VV-ECMO. Medical procedures during VV-ECMO are associated with a high risk of CA and should be planned with care. Also, the rate of ROSC was very high, only a small number of patients survived the overall VV-ECMO treatment course.
Variable Intrafamilial Expression of ABCB4 Disease
Authors: Zampaglione Lucia , Rougemont Anne-Laure , Rubbia-Brandt Laura , Abramowicz Marc , Guipponi Michel , Marchionni Enrica , McLin Valerie , Goossens Nicolas 
Published: August 2023

ABSTRACT
Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease with autosomal recessive inheritance caused by mutations in the ABCB4 gene. The clinical presentation of PFIC3 varies significantly, displaying incomplete penetrance without clear genotype-phenotype correlations. As such, the suitability of living-related liver donation for children with advanced disease has been questioned. We report here the long-term follow-up of a patient with PFIC3 resulting in decompensated cirrhosis at 11 years who successfully underwent living donor liver transplantation from his father, who carried the same ABCB4 homozygous mutation.