bluuebunny/crossref_metadata_2025_split huggingface dataset:
Latent Representation Modeling in Fine-Grained Dementia Classification: A Transformer-Based Approach with Adversarial-Contrastive regularization and FDG-PET data
Authors: kherchouche anouar , Ben Ahmed Olfa , Guillevin carole , Julian Adrien , Fernandez-Maloigne Christine 
Published: July 2023

<p>Advances in Artificial Intelligence play an important role in the development of modern Computer-Aided Diagnosis (CAD) systems. CAD software has greatly benefited from deep learning advances in disease detection. Nonetheless, these tasks remain challenging when it comes to the early stage of the disease where imaging atrophy is usually underrepresented in imaging data and annotated data are limited for efficient model training. Indeed, early disease diagnosis often requires discrimination between patients at the sub-category level, which is considered a fine-grained classification problem. The latter is a challenging task due to the subtle disease-specific patterns, clinically overlapping sub-categories (small variance), and hence the difficulty in learning medical clinically discriminant features. In this paper, we propose a transformer-based framework that optimally learns a clinically meaningful disease representation for fine-grained classification of early Alzheimer's disease conditions using 18F FluoroDeoxyGlucose Positron Emission Tomography (18F-FDG PET) images. The proposed method captures both local and global contextual clinical information from the whole image and learns a latent representation through a regularized objective function. The network training function is boosted using the Contrastive Learning (CL) paradigm. Yet, adversarial augmentation has been proposed for effective pairs mining for the optimization of the CL. The proposed method has been evaluated on six fine-grained classification tasks for AD detection and prediction on the ADNI dataset. Obtained results outperform recent state-of-the-art approaches.</p>
Feasibility of Battery-Powered Propulsion Systems for All-Electric Short-Haul Commuter Aircraft
Authors: Anker Markus Aasen , Hartmann Christian , Nøland Jonas Kristiansen 
Published: July 2023

<p>All-electric battery-powered aircraft have, over the last couple of years, had a clear path toward commercialization by the end of this decade. However, the development of smaller all-electric commuter aircraft has recently stagnated due to inherent technical limitations. To gain deeper insights into these challenges, this paper provides a detailed powertrain analysis of 9- and 19-seat all-electric commuter aircraft. Real-world mission profile data, obtained from 1500 flights in the Norwegian short-haul commuter network, are used as inputs. Regression analysis reveals that the cruising power needed is only about \SI{43}{\%} of the power needed for takeoff and climb. This work presents a comprehensive component-level weight distribution analysis of the all-electric powertrains investigated, and the required weight is shown to exceed the manufacturers' reported maximum takeoff weight (MTOW) of the two reference aircraft studied. However, small improvements in component performances could make electrification of the short-haul commuter network feasible, which is highlighted in a sensitivity study of the most critical electrical components. Additionally, our study highlights that the shortest missions are actually dimensioned by power rating rather than energy storage, adding an extra constraint on battery sizing for the shortest trips. </p>
Vysikaylo’ cumulative plasma cannon on the protection of the Earth from meteorites
Authors: Vysikaylo Philipp 
Published: July 2023

<p> De Broglie reported that particles behave like waves. The author proves that de Broglie waves of free electrons in the plasma tail of a meteoroid behave like electromagnetic waves in a quantum resonator (laser) and form a beam (jet) of high-energy electrons directed into the meteoroid. A jet of high-energy electrons formed in the plasma tail behind the meteoroid sprays the meteoroid with the help of a Coulomb explosion (or a series of them). Based on this idea, we proposed and investigated a new 4D inertial-polarization-quantum cumulative-dissipative <strong>Vysikaylo’s mechanism for the</strong> <strong>fragmentation of meteoroids</strong> and small comets (self-protection of the Earth from meteoroids) into simple ions and electrons. </p>
Perancangan Sistem Informasi Kontrakan Bu Jamilah Menggunakan Website
Authors: Nuraiman  , Kamdan  , Yustiana Indra 
Published: July 2023

Saat ini, manusia membutuhkan teknologi informasi untuk melakukan banyak hal. Dengan menggunakan teknologi informasi yang tepat, informasi yang diperlukan dapat dihasilkan dengan cepat sehingga keputusan dapat dibuat dengan cepat. Kontrakan bu Jamilah adalah satu tempat menginap atau kontrakan yang terletak di Cikarang dengan fasilitas kontrakan yang cukup baik. Pemilik kontrakan tersebut memiliki beberapa masalah seperti pemasaran kontrakan atau iklan kontrakan kurang maksimal, pemilik kontrakan kurangnya pengetahuan dalam pemasaran kontrakan didunia maya (internet). Pemilik kontrakan masih menyimpan data-data penyewa kontrakan hanya diarsip dalam bentuk foto copy ktp dan kartu keluarga sehingga dapat menyebabkan kehilangan arsip penyewa kontrakan. Untuk mengatasi masalah yang ada, peneliti merancang sistem informasi kontrakan yang dapat mempermudah pemilik kontrakan dalam mempromosikan kamar kontrakan dan menyimpan arsip pengguna jasa kontrakan. Peneliti menggunakan metode penelitian deskriptif dan teknik pengumpulan data observasi dengan cara melihat langsung kamar kontrakan bu jamilah. Sistem yang dibuat berbasis Website bersifat responsive. Peneliti merancang pembuatan aplikasi menggunakan metode waterfall. Peneliti menggunakan bahasa pemograman PHP dengan framework Codeginiter dan Bootstrap. Hasil dari penelitian ini pemilik kontrakan dapat dengan mudah mempromosikan kontrakan dan menyimpan arsip pengguna jasa kontrakan dengan baik.
Estrategia metodológica basada en la teoría de inteligencias múltiples para el aprendizaje de nomenclatura química orgánica
Authors: Pazmiño Celi Rosa Elena , Lucero Garcés Marco Fabián , Lucero Garcés Carlos Alberto , Garcés Alvear María Fernanda , Paredes Garcés María Elena 
Published: July 2023

El objetivo de este trabajo fue desarrollar una estrategia metodológica basada en la teoría de las Inteligencias Múltiples para el aprendizaje de nomenclatura química orgánica en los estudiantes de tercero de bachillerato de la Unidad Educativa “Juan Montalvo” de Ambato - Ecuador. El estudio, se enmarco en un enfoque cuantitativo con un diseño cuasiexperimental con un alcance descriptivo – comparativo. La población estuvo conformada por 72 estudiantes. Se aplicó una encuesta en escala Likert, escalas de evaluación del desarrollo de las inteligencias múltiples y una prueba de conocimientos de pre test y post test. Determinando que la mayor dificultad, se presenta al aplicar la nomenclatura en la vida diaria, además, presentan dificultades al desarrollar las inteligencias: intrapersonal e interpersonal, la cinestesia y la lógica matemática, por lo que se utilizaron estrategias metodológicas activas como Mindfulness, aprendizaje colaborativo, la gamificación, Flipped classroom y el Aprendizaje basado en proyectos. Los resultados demuestran que aplicar estrategias metodológicas basadas en inteligencias múltiples incrementa el rendimiento académico en un 25%.
Reconociendo la importancia del dolor crónico, desde la teoría de la compuerta, pasando por la neuromatriz, hasta la educación en neurociencias del dolor(PNE)
Authors: Ruiz Gaviria Neider , Martinez Ayola Agustin 
Published: July 2023

El dolor crónico es una epidemia del siglo XXI que plantea múltiples retos tanto a nivel científico-médico como económico, la carga de gastos en salud y determinantes en salud secundaria a estos son de gran importancia para los sistemas sanitarios de todo el mundo. Un inicio para comenzar a despejar este panorama es la intervención del manejo del dolor desde las neurociencias. Desde que salió a la luz la” teoría de las compuertas" de Melzack y Wall en 1965. Posteriormente apareció la "teoría de la neuromatrix" permitió integrar elementos pueden alterar la forma en que reacciona el sistema nervioso central y prolongar el dolor crónico. Se empieza a conocer la importancia de la plasticidad neuronal. Por último, se reconoce la importancia de la educación en neurociencia del dolor en el tratamiento del dolor crónico. Se prevé que la investigación futura compare con otras intervenciones y evalúe los efectos de esta educación a largo plazo. Se realizó una investigación exhaustiva en las bases de datos científicas: Science Direct, PubMed, Scielo, Elsevier, Springer, Oxford Academic, Dialnet.
Service Excellent dan Kualitas Produk : Sebuah Kajian Tentang Loyalitas Nasabah
Authors: Fatimah Sitti , Abdullah Salma , Amniar Nurul Hifdziyah 
Published: July 2023

Penelitian ini memiliki tujuan untuk mengetahui pengaruh secara parsial dan simultan antara Service excellent dan kualitas produk terhadap loyalitas nasabah.. Penelitian ini merupakan penelitian kuantitatif, Teknik pengumpulan data yang digunakan dalam penelitian ini adalah data primer. Populasi yang digunakan dalam penelitian ini adalah sebanyak 219 pegawai IAIN Bone yang telah menjadi nasabah Bank Muamalat Cabang pembantu Bone, dan sampel yang digunakan dalam penelitian ini sebanyak 142 pegawai dengan menggunakan rumus slovin. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis regresi linear berganda. Penelitian ini menggunakan bantuan software pengolahan data SPSS 24.0. Hasil yang diperoleh pada analisis secara parsial menjelaskan bahwa Service excellent berpengaruh secara signifikan terhadap loyalitas, sedangkan secara parsial hasil yang di dapatkan adalah kualitas produk berpengaruh signifikan terhadap loyalitas nasabah pada Bank Muamalat Indonesia Cabang Pembantu Bone. Adapun hasil analisis secara simultan di peroleh hasil bahwa Service excellent dan kualitas produk berpengaruh signifikan terhadap loyalitas nasabah sebesar 64,4%.
RENAL ARTERY ANEURYSM – A CASE REPORT FROM KP
Authors: Nasim Omer , Rustam Zainab , Khan Zubair Ahmed , Ahmad Jamil 
Published: July 2023

Renal artery aneurysm (RAA) is a rare lesion and occurs in less than 1% of the population. There are multiple available treatment options which depend on the type of aneurysm and the timely diagnoses of the condition. Understanding these options is important; endovascular techniques, renal auto-transplantation and nephrectomy maybe indicated. A case of RAA in the left renal artery which was surgically treated with radical nephrectomy because of the nature of the presentation which was an emergency and was managed swiftly to save the patient’s life.
A atenção conferida ao segmento racional negro no exame CELPE-BRAS: apagamentos e problematizações
Authors: Moraes Robson 
Published: July 2023

Este artigo é fruto de uma pesquisa de abordagem qualitativa e documental, e apresenta resultados parciais de investigações sobre à atenção dada ao segmento negro nos conteúdos dos Elementos Provocadores - EPs da prova oral do CELPE-Bras. A amostragem da investigação é formada por 20 EPs, da edição do exame de 2004.1. Para o levantamento dos dados, foi realizada a escolha de conteúdos textuais dos EPs com o fito de verificar se eles abordam questões relativas às relações étnico-raciais. Caso existindo indícios de tais elementos, nota-se também se as perguntas dos roteiros de interação relativas aos EPs selecionados espelham a diversidade étnico-cultural do país. De outra forma, se apresentam a pluralidade cultural brasileira de forma distorcida ou se tais questões são invisibilizadas. Além de se explorar como a cultura afro-brasileira é exposta, busca-se interrogá-la nos conteúdos desses materiais. São versados na investigação categorias como: língua/linguagem, cultura, raça, fenótipo, branquitude e racismos. A partir do que é recomendado pela lei 10.639/2003, este escrito pretende contribuir para os estudos do cenário de ensino de português para estrangeiros com vistas a enfatizar a pertinência da diversidade étnico-racial brasileira como parte constituinte do campo de ensino e aprendizagem de português. Por fim, os resultados apontam que enquanto as questões referentes ao segmento racial negro recebem pouquíssima atenção, as questões relativas a branquitude é supervalorizada nos materiais apreciados.
Palavras-Chave: Exame Celpe-Bras; Segmento racial negro; Racismo.
Comparison of Left Ventricular Global Longitudinal Strain with Ejection Fraction as a Predictor for Peri-operative IABP Insertion in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Pilot Study
Authors: Kumar Sanjeev , Malik Vishwas , Chauhan Sandeep , Das Devishree , Hote Milind P. , Devagourou V. 
Published: July 2023

Background:
Prophylactic use of intra-aortic balloon pump (IABP) mainly depends on left ventricular (LV) systolic function. Global longitudinal strain (GLS) is a robust prognostic parameter for LV strain. It has proved to be more sensitive than LV ejection fraction (EF) as a measure of LV systolic function and is a strong predictor of outcome.

Aim:
To determine whether GLS can be used as a reliable marker and its cut-off value for IABP insertion in patients undergoing elective off-pump coronary artery bypass grafting (OPCABG).

Settings and Design:
A prospective observational clinical study which included 100 adult patients scheduled for elective OPCABG.

Materials and Methods:
Two-dimensional (2D) speckle tracking echocardiography (STE)-estimated GLS was computed and compared with LV EF measured by three dimensional (3D) echocardiography for the insertion of IABP. The intensive care unit (ICU) parameters were correlated with echocardiographic parameters to predict early post-operative outcome.

Results:
IABP insertion correlates better with GLS (post-revascularization > pre-revascularization) than with 3D LV EF. Receiver operating characteristic (ROC) curve analysis revealed the highest area under the curve (AUC, 0.972) with a cut-off value of > -9.8% for GLS compared to 3D LV EF (AUC, 0.938) with a cut-off value of ≤ 44%. ICU parameters show better correlation with E/e’> GLS > WMSI than 3D LV EF.

Conclusion:
GLS is a better predictor of IABP insertion compared to 3D LV EF in patients undergoing OPCABG.
Prognostic role of metabolic 18F-FDG PET/CT parameters and hematological prognostic indicators in patients with colorectal cancer
Authors: Cengiz Arzu , Yersal Özlem , Ömürlü İmran Kurt , Yürekli Yakup 
Published: July 2023

Background:
The aim of this study is to evaluate the role of preoperative 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography (PET/CT) parameters, including maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG), hematologic prognostic indicators in patients with colorectal cancer (CRC) in terms of predicting prognosis.

Methods:
One hundred and one patients who had undergone 18F-FDG PET/CT for initial staging were evaluated retrospectively. Patient data including pathologic stage at presentation, histology, tumor location, and overall survival (OS) were analyzed. Neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), serum carcinoembryonic antigen (CEA) (ng/mL), CA-125 (cancer antigen 125) (U/mL), and CA19-9 (U/mL) levels, which were obtained within 2 weeks of the PET/CT examination, were used for hematological data.

Results:
The TNM Classification of Malignant Tumors stage and PET/CT parameters, including SUVmax, MTV, and TLG, were found to be correlated with survival rate in univariate analysis (P < 0.05). All hematological markers excluding PLR were also significantly associated with survival time. Receiver operating characteristics (ROC) analysis revealed that the optimal SUVmax cutoff value for predicting survival time in patients with CRC was >17.9 (Area under curve (AUC) = 0.625; P < 0.05). The calculated sensitivity and specificity values for this cutoff were 60% and 65.7%, respectively. To predict the survival time in these patients, the optimal MTV cutoff value was >34.29 (AUC = 0.775; P < 0.001; sensitivity = 85%; specificity = 62.3%). The optimal TLG cutoff value for predicting survival time was >270.4 (AUC = 0.790; P < 0.001; sensitivity = 77.5%; specificity = 68.9%).

Conclusions:
FDG PET/CT metabolical parameters are useful for predicting the prognosis in patients with CRC. High preoperative NLR and high tumor markers were also shown to be negative independent prognostic factors in these patients.
Functional Outcome of Osteosynthesis with PHILOS in Elderly Patients: Experience at Tertiary Care Centre
Authors: Kushwaha Narendra Singh , Saini Sushil Kumar , Verma Ashutosh , Mohan Ravindra , Saroj Atul Kumar , Singh Arpit , Prajwal M. C. 
Published: July 2023

Background:
Increased risk of proximal humerus fractures are seen in elderly group as their bones are osteoporotic or brittle. Mode of trauma in elderly patients with severe osteoporosis, fractures usually resulted from low velocity indirect trauma while high velocity trauma like road traffic accident was the cause of these fractures in younger age group. Surgery can be an option to obtain a better functional outcome or when a complex fracture needs to be fixed. With the advantages and the paucity of data on the functional outcome and efficacy of the following internal fixation with the PHILOS plate for displaced proximal humerus fractures in mind, the present study was planned.

Methodology:
Patients who fulfilled the selection criteria were informed about the study and were then enrolled. Following the surgery, patients were followed up regularly at six weeks, three months, and six months. Final outcome was analyzed by Constant Shoulder Score. Christopher Constant, with the help of the late Alan Murley during the years 1981–1986, devised the Constant Score, which was first presented in a university thesis in 1986 and whose methodology was later published in 1987.

Results:
A total of 30 patients sustained with proximal humerus fractures were studied. In this study of final assessment were Found 73.2 % good to excellent outcome by using the Constant Shoulder Score.

Conclusion:
Following this study, the inference can be drawn that proximal humerus internal locking system for the management of proximal humerus fractures give a good functional outcome in most patients. Hence PHILOS plate application for fixation of fracture proximal humerus in elderly patients hence allowing early mobilization of the shoulder.
Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial
Authors: Hussain Asif , Saini Sushil Kumar , Patel Jaydeep , Pal Chandra Prakash , Chahar Hemant Singh , Yadav Rohit 
Published: July 2023

Context:
Osteoporosis remains a significant public health problem in many parts of the world, including India. The efficacy of oral bisphosphonates is lower because of poor compliance. Annual treatment with zoledronic acid has been reported to improve outcomes.

Objective:
To study the benefits and side effects of zoledronic acid in patients with osteoporosis.

Methods:
This is a blinded randomized clinical trial conducted at a government hospital. Patients aged 50–89 years with bone mineral density (BMD) T score < −2.5 or < −1.5 with 2 mild vertebral fractures or 1 moderate vertebral fractures were randomized to receive placebo versus zoledronic acid. A total of 200 patients were be studied, 100 in each arm. Zoledronic acid was given in single dose (15-min infusion). Serum calcium, dual-energy X-ray absorptiometry, and lateral spine radiographs were performed at enrollment and after 12 months. The primary endpoint was combined risk of new-onset vertebral and hip fractures. The secondary endpoints were new-onset vertebral and hip fractures and BMD.

Results:
The primary outcome was reduced by 79% during the 1-year period in zoledronic acid, compared to placebo (3% in the treatment group vs. 14% in the placebo group; relative risk (RR): 0.21; 95% confidence interval [CI]: 0.06–0.72, P = 0.01). Treatment with zoledronic acid reduced the risk of new-onset vertebral fracture by 82% (RR: 0.18; 95% CI: 0.04 to 0.79; P = 0.02). No significant differences in new-onset hip fractures were noted (RR: 0.33; 95% CI: 0.03–3.15; P = 0.33). A significant increase in BMD score was found after treatment with zoledronic acid compared to placebo group (P < 0.05). No serious adverse events were noted.

Conclusion:
Annual infusion of zoledronic acid reduces the risk of combined fracture of vertebra and hip and improves the bone mineral density in osteoporotic patients.
Functional Outcome (Short Term) of Modular Cementless Bipolar HemiArthroplasty (Hydroxyapatite-Coated Stem) for Fracture Neck of Femur in the Elderly
Authors: Shukla Navin K. , Keshkar Lata , Mukherjee Jayanta , Kumar Ratnesh , Singh Shivendra , Agrawal Alok C. 
Published: July 2023

Background:
Bipolar hemiarthroplasty (BHA) is commonly used to treat fracture neck of femur (NOF) in the elderly, despite the fact that the appropriate treatment of fracture NOF is still controversial. In this prospective study, the functional outcomes of NOF fracture after surgery in the elderly, who underwent BHA with a fully coated hydroxyapatite stem with a collar (CORAIL Stem).

Materials and Methods:
Forty-three consecutive elderly patients with NOF fracture underwent BHA through the lateral Hardinge approach. They were followed up after surgery for 1 year. Two patients expired and one was lost to follow-up and were not included in the study. Postoperative follow-up was done every 4–20 weeks and thereafter at intervals of 3–12 months. Harris hip score (HHS) was recorded at each follow-up visit and complications were noted.

Results:
Forty patients with a mean age of 77 (62–93) years were followed up after surgery for 1 year. Two patients (4.7%) expired and one (2.3%) was lost to follow-up and were not included in the study. HHS of our cohort of patients averaged 86 (72–99), which falls in the category of a good outcome (80–90). A mild negative correlation (correlation index − 0.2) of age and HHS was observed but was not significant (P = 0.56). Significantly more female patients suffered from NOF fracture (male - 13 [32.5%]: female - 27 [67.5%]; P = 0.03). The left side was injured more often than the right (left 23 [57.5%], right 17 [42.5%]; P = 0.34). Thirty-three patients (83.5%) had one or more comorbid conditions. The mean HHS of female and male patients was 86.41 and 85.39, respectively. This difference was not significant (P = 0.33). There was no difference in outcome, whether an injury occurred to the dominant or nondominant extremity. Complications occurred in seven (17.5%) patients.

Conclusions:
In the first follow-up year, a good functional outcome with a low complication (17.5%) and mortality rate (4.7%) was observed. Twenty-seven patients (62%) were absolutely pain-free. There were no dislocations, revisions, or additional surgeries in any patients. Most patients returned to their preinjury activity level. To conclude, the procedure is safe and rewarding in the elderly.