bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pilot implementation of two specific problem lists before and after solid organ transplantation into routine care
Authors: Higgen Sanna , Müller Evamaria , Barten Markus J. , Eickhoff Doreen , Grahammer Florian , Härter Martin , Bart Sabine , Sterneck Martina R. , Buchholz Angela 
Published: January 2025

IntroductionPsychosocial distress and mental health problems are common in patients before and after solid organ transplantation and can negatively affect morbidity, mortality, and adherence. Even though regular screening is recommended to identify patients with high levels of distress, the implementation in routine care has been insufficient so far.MethodsTwo newly developed problem lists for patients before and after transplantations were pilot implemented for 8 weeks at the Medical Center Hamburg Eppendorf (UKE) to identify factors facilitating and impeding their implementation.ResultsHealth care professionals evaluated its appropriateness, feasibility, and the cooperation with the psychologists before (HCPs: n = 23) and after (HCPs: n = 19) the implementation. Four psychologists assessed the appropriateness and feasibility by answering to open-ended and close-ended questions. Additionally, patients before (n = 8) and after (n = 100) transplantation filled out the screening and rated its acceptance. Only the data of the patients after transplantation were analyzed due to the small sample size of patients before transplantation. HCPs and psychologists rated the screenings as very appropriate [HCPs: M = 3.84 (SD = 0.77) to M = 4.32 (SD = 0.58)]. It was also highly accepted among patients [M = 4.23 (SD = 0.85) to M = 4.68 (SD = 0.65)]. Contentment with the psychological support and understanding of the mental health problems among HCPs increased significantly from before to after the implementation (U = 107.50, p &lt; 0.05, r = 0.33; U = 107.00, p &lt; 0.05, r = 0.34). The feasibility of the problem list post-Tx in routine care, however, was seen as challenging [HCPs: M = 3.11 (SD = 1.05) to M = 3.47 (SD = 1.07)].DiscussionThe distress screening was accepted and improved the cooperation between different professions. Barriers to implementation can be lack of staff and resources. Future studies should assess the adoption and sustainability of the screening in routine care.
Exploring the relationship between resilience, sense of coherence, and social support in a sample of nurses during the spread of COVID-19: a mediation analysis study
Authors: Rohani Camelia , Ahmadi Mehrnaz , Seyedtabib Maryam , Mehdipoorkorani Ladan 
Published: January 2025

BackgroundDuring the spread of COVID-19, nurses on the front line of fighting the disease experienced severe psychological pressures. The ability to adapt to difficult situations is an essential requirement for maintaining individuals’ endurance during a crisis. This study was designed to explore the relationship between three outcome variables of resilience, sense of coherence (SOC), and perceived social support in a sample of Iranian nurses during the spread of the COVID-19 pandemic.MethodsA cross-sectional study with a correlational design was conducted on 360 registered nurses from six university hospitals during the seventh wave of COVID-19 in our society. Data collection was conducted by the demographic information questionnaire, the Connor–Davidson Resilience Scale (CD-RISC), the Sense of Coherence Scale (SOC-13), and the Multidimensional Scale of Perceived Social Support (MSPSS).ResultsThe results of the structural equation modeling (SEM) showed that social support had a direct positive effect on the SOC (β = 0.498, p &lt; 0.001), and the SOC had a direct positive effect on the resilience (β = 0.688, p &lt; 0.001). Furthermore, we found an indirect effect of social support on resilience through the complete mediating role of the SOC.ConclusionThe full mediating role of SOC in the relationship between social support and resilience showed that nurses with a higher level of SOC had a better understanding of social support, and this can influence their resilience in the COVID-19 crisis. This is theoretical support for the application of the salutogenic approach to health intervention plans to promote a healthy orientation in nurses toward mobilizing resources.
Chronic low back pain and postural instability: interaction effects of pain severity, age, BMI, and disability
Authors: Alshahrani Adel , Reddy Ravi Shankar , Ravi Sunil Kumar 
Published: January 2025

ObjectivesThis study aimed to (1) compare postural sway patterns between individuals with chronic low back pain (CLBP) and asymptomatic controls, (2) evaluate correlations between pain severity and postural stability variables, and (3) assess the interaction effects of age, BMI, pain severity, and disability on postural stability under eyes-open and eyes-closed conditions.MethodsPostural stability (sway area, sway velocity, CoP displacement) was assessed in 88 CLBP patients and 88 controls using a stabilometric platform. Pain severity (VAS) and disability (ODI) were recorded alongside demographic data. Statistical analyses included t-tests, Pearson’s correlations, and ANOVA to explore group differences, correlations, and interaction effects.ResultsChronic low back pain patients exhibited significantly greater postural sway across all conditions, with larger sway area (16.80 ± 6.10 cm2 vs. 11.50 ± 4.10 cm2, p = 0.004) and higher sway velocity (4.10 ± 1.40 cm/s vs. 2.90 ± 1.00 cm/s, p = 0.009) under eyes-closed conditions. Pain severity correlated with sway velocity (r = 0.52, p = 0.003) and CoP displacement (r = 0.57, p = 0.002). Interaction effects indicated greater instability in older, obese individuals with severe pain and high disability.ConclusionChronic low back pain is associated with impaired postural stability, influenced by pain severity, BMI, age, and disability. Targeted interventions addressing these factors are essential for improving balance and reducing fall risk.
The dynamics of organ donation in Palestine: legal, religious, and socioeconomic perspectives in a complex political and economic landscape
Authors: Hattab Muayad K. , Rahhal Belal M. , Mahamid Fayez , Adas Noor O. , Dawas Rana , Jaradat Nidal , Al Zabadi Hamzeh , Ali Iyad , Kielani Jamal , Musleh Ali , Khaled Ghassan 
Published: January 2025

BackgroundOrgan donation in Palestine is influenced by a unique blend of legal, religious, and socioeconomic factors compounded by the region’s political and economic instability. Despite the increasing need for organ transplantation, public hesitation and misconceptions hinder participation. This study aimed to explore these dynamics, identify barriers, and provide insights into improving organ donation practices in Palestine.MethodsA quantitative survey was conducted among 639 Palestinian adults residing on the West Bank. The survey assessed participants’ attitudes, awareness, and perceptions of organ donation across three domains: religious/psychological, medical, and legal. The data were analyzed using chi-square tests and three-way ANOVA to explore differences in attitudes based on demographic factors such as sex, academic level, and place of residence.ResultsThe study revealed significant variability in public attitudes toward organ donation, with 43.4% willing to donate organs after death but 30% still opposed. Religious and psychological awareness significantly influenced participants’ attitudes, with 40.35% agreeing that organ donation aligns with their beliefs. Medical awareness was higher, with 48.8% feeling informed about the process. Legal awareness was moderate, with 44.85% understanding of the legal framework. The analysis showed no significant demographic differences in attitudes toward organ donation.ConclusionPublic awareness, religious beliefs, and socioeconomic conditions play crucial roles in shaping organ donation attitudes in Palestine. This study highlights the need for targeted educational campaigns that integrate religious perspectives and raise awareness about the legal and medical aspects of organ donation. Strengthening legal frameworks and healthcare infrastructure will be key to improving organ donation rates and ensuring ethical practices in the region.
Interaction between sleep duration and physical activity on mortality among cancer survivors: findings from National Health and Nutrition Examination Surveys 2007–2018
Authors: Chen Ruyan , Han Jianglong , Li Si , Deng Haiyu , Jian Tingting , Huang Zheyu , Wei Yuxuan , Fu Zhenming 
Published: January 2025

BackgroundSleep duration and physical activity (PA) are critical factors influencing mortality risk. However, the interaction between sleep duration and PA with mortality risk among cancer survivors has not been well explored.MethodsThis cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) spanning 2007–2018. Multivariable Cox regression analysis and restricted cubic splines were employed to evaluate the hazard ratios (HRs) and 95% confidence intervals (CIs) of the association of sleep duration and PA with mortality risk in cancer survivors. Multiplicative and additive interaction terms were constructed to assess interaction effects.ResultsThe study included a total of 2,528 adult cancer survivors (aged≥20 years). Sleep duration exhibited a U-shaped association with all-cause and cancer-specific mortality, while demonstrating an inverted L-shaped association with cardiovascular disease (CVD) mortality. Compared to physically inactive participants, those with adequate PA had lower risks of all-cause mortality (HR = 0.542, 95% CI: 0.540–0.543), cancer mortality (HR = 0.486, 95% CI: 0.484–0.488), and CVD mortality (HR = 0.759, 95% CI: 0.755–0.763) among cancer survivors. A significant additive interaction was found between extreme sleep duration and PA on all-cause mortality risk among cancer survivors (long sleep duration: relative excess risk due to interaction (RERI) = 1.514, 95% CI: 1.504–1.525; short sleep duration: RERI = 0.725, 95% CI: 0.713–0.737).ConclusionExtreme sleep duration and lack of PA were associated with mortality risk in cancer survivors independently and jointly. Maintain appropriate sleep duration and doing regular PA may synergistically improve cancer survival among cancer survivors.
The ethics of artificial intelligence use in university libraries in Zimbabwe
Authors: Tsekea Stephen , Mandoga Edward 
Published: January 2025

IntroductionThe emergence of artificial intelligence (AI) has revolutionised higher education teaching and learning. AI has the power to analyse large amounts of data and make intelligent predictions thus changing the whole teaching and learning processes. However, such a rise has led to institutions questioning the morality of these applications. The changes have left librarians and educators worried about the major ethical questions surrounding privacy, equality of information, protection of intellectual property, cheating, misinformation and job security. Libraries have always been concerned about ethics and many go out of their way to make sure communities are educated about the ethical question. However, the emergence of artificial intelligence has caught them unaware.MethodsThis research investigates the preparedness of higher education librarians to support the ethical use of information within the higher and tertiary education fraternity. A qualitative approach was used for this study. Interviews were done with thirty purposively selected librarians and academics from universities in Zimbabwe.ResultsFindings indicated that many university libraries in Zimbabwe are still at the adoption stage of artificial intelligence. It was also found that institutions and libraries are not yet prepared for AI use and are still crafting policies on the use of AI.DiscussionLibraries seem prepared to adopt AI. They are also prepared to offer training on how to protect intellectual property but have serious challenges in issues of transparency, data security, plagiarism detection and concerns about job losses. However, with no major ethical policies having been crafted on AI use, it becomes challenging for libraries to full adopt its usage.
Decoding gene expression dynamics in planktonic and biofilm cells of Streptococcus mutans: regulation and role of mutanofactin genes in biofilm formation
Authors: Afzal Muhammad , Carda-Diéguez Miguel , Bloch Susanne , Thies Leon G. S. , Mira Alex , Schäffer Christina 
Published: January 2025

IntroductionDental caries is the most prevalent chronic infectious disease globally, with Streptococcus mutans recognized as a primary causative agent due to its acidogenicity and robust biofilm-forming ability. In S. mutans biofilm formation, the role of autoinducers has been extensively studied, while the influence of other small molecules remains largely unexplored. Mutanofactins, a class of polyketide/non-ribosomal lipopeptide secondary metabolites, are emerging as potential modulators of S. mutans biofilm development.MethodsTranscriptomic analysis was conducted to examine gene expression patterns in S. mutans NMT4863 across distinct growth phases and lifestyles, aiming to identify metabolic factors influencing biofilm formation. Transcriptomic profiles were compared between cells in early-, mid-, and late-exponential-, and stationary phase, as well as between planktonic and biofilm cells. Differentially expressed genes were identified, and pathway analyses revealed significant alterations in key metabolic and regulatory pathways. Specifically, the biosynthetic mutanofactin gene cluster was analyzed via quantitative real-time polymerase chain reaction.ResultsSeveral genes and operons were differentially expressed across the tested growth phases, with 1,095 genes showing differential expression between stationary-phase, planktonic and biofilm cells. Pathway analysis revealed significant changes in ascorbate metabolism, carbohydrate utilization and transport systems, lipoic acid metabolism, bacterial toxin pathways, two-component regulatory systems, and secondary metabolite biosynthesis. Notably, expression of the muf gene cluster, was elevated in early exponential-phase cells relative to stationary-phase cells. Additionally, the mufCDEFGHIJ genes were identified as components of a single transcriptional unit (muf operon). MufC, a transcriptional regulator of the TetR/AcrR-family, acts as a positive regulator of the muf operon in strain NMT4863. Bioinformatic analysis pinpointed a 20-bp regulatory sequence in the muf operon promoter region (5′-AAATGAGCTATAATTCATTT-3′). Interestingly, the muf operon was found to be significantly downregulated in biofilm cells.ConclusionThis study provides key insights into gene expression dynamics that drive biofilm formation in S. mutans NMT4863, with a particular emphasis on the role of the muf operon. This operon is governed by the TetR/AcrR-family regulator MufC and plays a central role in biofilm development, offering a novel perspective on the molecular basis of S. mutans biofilm formation and resilience.
Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies
Authors: Assefa Ebrahim Msaye , Abdu Seid Mohammed 
Published: January 2025

IntroductionMale infertility, often attributed to insufficient production of healthy and active sperm, can be exacerbated by electromagnetic radiation emitted from mobile phones, which disrupts normal spermatogenesis and leads to a notable decline in sperm quality. The main targets of mobile phone-induced damage in the testes are Leydig cells, seminiferous tubules, and sperm cells. The aim of this systematic literature review is to identify histopathological changes in the testes due to mobile phone radiation exposure and to examine its effects on sperm parameters in experimental animals.MethodsIn this systematic review, an extensive literature search was conducted across databases such as PubMed, ScienceDirect, Hinari, and Google scholar.ResultsA total of 752 studies were identified for screening, and 18 studies were deemed eligible for data extraction. Studies have identified histopathological alterations in testicular tissue caused by mobile phone radiation, such as reduced seminiferous tubule diameter, tunica albuginea and germinal epithelial thickness, Leydig cell hypoplasia, and increased intertubular space. Consistent exposure to mobile phone radiation has been shown to significantly reduce sperm count, motility, and viability, while also increasing abnormal sperm morphology in male rats, mice, and rabbits.ConclusionAnimal studies indicate that electromagnetic radiation from mobile phones can negatively impact testicular tissue and sperm parameters, including sperm count, motility, viability, and morphology. As a precaution, preventive measures are recommended to minimize potential risks from mobile phone exposure, and further research is needed to fully understand its effects on human reproductive health.
Influence of time-of-day on neuromuscular performance in team sport athletes: a systematic review and meta-analysis
Authors: Martin-López Julio , Pérez-López Alberto , Varillas-Delgado David , López-Samanes Álvaro 
Published: January 2025

IntroductionAlthough circadian rhythms have been shown to influence some neuromuscular performance tasks, the time-of-day effect on team sports performance athletes remains equivocal. This study aimed to examine the existing evidence concerning diurnal variations in neuromuscular performance in professional and semi-professional team sports athletes using a meta-analytic approach.MethodsA literature search was conducted through three different databases: PubMed, SportDiscus and Web of Science. Article selection was made based on the following inclusion criteria: team sports athletes, professional or semi-professional athletes, neuromuscular performance, testing protocols and time-of-day testing times. Neuromuscular performance parameters such vertical jump capacity (i.e., squat and countermovement jump), agility and isometric strength were included in the analysis. Testing protocols that specifically assessed these parameters across morning (AM) and late afternoon/evening (PM) periods were considered were extracted from the selected studies.ResultsTen studies met the inclusion criteria for qualitative synthesis and five for quantitative synthesis. Meta-analysis indicated lower countermovement jump in the AM compared to with PM (mean difference, −1.44; 95% CI −2.80 to −0.08; p = 0.04) and higher agility performance (mean difference 0.42; 95% CI 0.09–0.74; p = 0.01) in PM comparing with AM. No differences were reported in isometric strength and squat jump performance (p &gt; 0.05).ConclusionNeuromuscular performance is higher in the late afternoon or early evening compared to morning schedules in team sport athletes. Hence, time-of-day variations need to be considered when evaluating neuromuscular performance in professional and semi-professional team sports athletes.
The influence of digital village construction on agricultural green development-based on the mediate role of industrial structure upgrading
Authors: Li Zhaoguang , Hu Kai , Shi Qinying 
Published: January 2025

IntroductionLeading the green transformation of agriculture through the digital economy is a crucial step toward high-quality agricultural growth. The role and mechanism of China's digital rural construction in promoting the green development of the whole process of agricultural production needs further analysis.MethodsBased on the panel data of prefecture-level cities in Henan Province from 2013 to 2022, we used the entropy topsis model, the fixed effect model, the Tobit regression model, the intermediate effect model, and the threshold effect model, aiming to explore the effects of digital village construction on agricultural green development and their regional differences, impacts paths and non-linear effects.ResultsThe study found the following: (1) The level of agricultural green development and the digital village construction have increased in Henan province, with the latter exhibiting a spatial clustering phenomena. (2) Digital village construction has a significant positive effect on green agricultural development, but this effect does not exist in mountainous areas. (3) The digital village construction can impact green agricultural development through the updating of agricultural structures. (4) The positive influence of digital village construction on green agricultural development is non-linear, with a single-threshold and increasing marginal effects.DiscussionThese findings provide references for other countries to use digital elements to promote green and sustainable development of agriculture. The main contribution of this study is to explore the role of agricultural industrial structure upgrading in the impact of digital rural construction on agricultural green development.
Surveillance of Mycoplasma agassizii in Texas tortoises (Gopherus berlandieri) for translocation with emphasis on treatment and recovery
Authors: Moeller Christin A. , Perales Saren , Rodriguez Wraith , Martin Alynn M. , Eversole Cord B. , Rideout-Hanzak Sandra , Crump Paul , Hilton Clayton D. , Henke Scott E. 
Published: January 2025

BackgroundTexas tortoises (Gopherus berlandieri) are a Texas-state threatened species. Translocation is often suggested as a mitigation option; however, disease status and the potential for spread must be considered prior to such efforts. Mycoplasma infection of the upper respiratory tract is a concern within tortoise populations, which requires monitoring so translocation efforts do not inadvertently spread the disease.ObjectivesWe determined and compared the prevalences of Mycoplasma agassizii in Texas tortoises from donor and recipient sites in southern Texas prior to translocation, treated Mycoplasma agassizii-infected tortoises with danofloxacin, and developed alternate Mycoplasma agassizii treatments for Texas tortoises.MethodsWe collected 171 and 23 Texas tortoises from a 270-ha and a 100-ha donor site and recipient site, respectively. We began a regimen of danofloxacin (6 mg/kg body weight injected subcutaneously every other day for 30 days) for tortoises with clinical signs (N = 20). We noted an additional 10 tortoises began displaying clinical signs of upper respiratory tract disease (URTD) after translocation, so we designed a trial to test tulathromycin (5 mg/kg body weight given intramuscularly once/week for 7 weeks) or oxytetracycline (8 mg/kg body weight given subcutaneously once/day for 14 days) as Mycoplasma treatments for symptomatic tortoises.ResultsWithin the donor and recipient sites, 56 (32.7%) and 8 (34.8%), respectively, had antibody titers suggestive of past exposure. Eighteen tortoises from the donor site (10.5%) and 2 from the recipient site (8.7%) displayed clinical signs (i.e., clear serous nasal discharge, conjunctivitis, and palpebral edema) consistent with Mycoplasmal URTD upon initial collection, even though all polymerase chain reaction (PCR) results were negative for active shedding of Mycoplasma agassizii. We ceased treatment after the first dose of danofloxacin due to adverse reactions, which only began to subside after 72 h from the initial dose. Neither tulathromycin or oxytetracycline caused the clinical signs of URTD to subside after a 50-day treatment period.ConclusionMycoplasma is a persistent issue facing Texas tortoises. Stressors, such as translocation, can cause Mycoplasma-seropositive tortoises to display clinical symptoms of URTD, which can abate without treatment, once the stressor subsides.ImplicationsDanofloxacin, the recommended treatment for Mycoplasma infection in tortoises, is too potent for Texas tortoises.