bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Parents in the Gender Role Identity Formation of Offspring- An Exploratory Study.
Authors: Chowdhury Shreya , Bhattacharya Suvosree , Bhattacharya Surajit , Bhattacharya Anjan 
Published: March 2023

Abstract
Gender role identity tends to shape an individual’s self-concept, playing a significant role in shaping their behaviour and interpersonal relationship patterns across different societies, races, and ethnicities. This study explores the relationship between perceived parenting styles (authoritarian, authoritative, and permissive for both parents) and gender role identity in young adults, and also the pattern of gender role identity of parents and their offspring. The sample consisted of 100 young adults (M=20.60, SD=1.98) and both of their parents (father and mother). Both the young adults and their parents responded to the Bem Sex-Role Inventory, whereas only young adults responded to the Parental Authority Questionnaire. Descriptive statistics showed that out of 100 young adults, 38% identified as androgynous, followed by feminine (29%), masculine (12%), and undifferentiated (21%). 54% of male young adults rated themselves as androgynous, whereas 46% of females identified as feminine. A considerable proportion of the parents reported themselves as androgynous (both 48%). A significant correlation was found between permissive parenting style in mothers and undifferentiated gender role identity in young adults (r= 0.75, p= 8.1e-05). A positive, moderately significant correlation was also found between fathers' permissive parenting style and masculinity in young adults (r= 0.83, p= 0.00093). This information will help us understand parents' role in gender identity formation and may also help us formulate management plans in terms of the parent-child relationship and their gender role identity.
On the Consistent Construction of Ipsative Tests
Authors: Vaughan Martin Paul , Demes Kali A , Glowinkowski Steve Paul 
Published: March 2023

Abstract
The need for consistent construction of ipsative tests to avoid the introduction of hard-coded `errors-by-design' is highlighted A set of necessary criteria for consistent construction is found and recommended. It is shown that for ipsative tests involving P scales with more than M=2 comparisons per item, the consistent combinations of P and M are in fact few and far between for tests with a manageable numbers of items. The introduction of errors through badly designed scoring methods is also illustrated and explained via analysis.
Prognostic value of post-operative inflammatory biomarkers in colorectal cancer patients: Systematic Review and Meta-Analysis.
Authors: Gwenzi Tafirenyika , Zhu Anna , Schrotz-King Petra , Schöttker Ben , Hoffmeister Michael , Edelmann Dominic , Brenner Hermann 
Published: March 2023

Abstract
Background
Post-operative inflammation in cancer patients can be modulated by drugs and diets, but evidence on its prognostic role, which would be crucial for personalized treatment and surveillance schemes, remains rather limited.
Aim
To systematically review and meta-analyse studies on the prognostic value of post-operative C-reactive protein (CRP)-based inflammatory biomarkers among patients with colorectal cancer (CRC) (PROSPERO#: CRD42022293832).
Methods
PubMed, Web of Science and Cochrane databases were searched until February 2023. Studies reporting associations between post-operative CRP, Glasgow Prognostic Score (GPS) or modified Glasgow Prognostic Score (mGPS) with overall survival (OS), CRC-specific survival (CSS) and recurrence-free survival (RFS) were included. Hazard ratios (HRs) with 95% confidence intervals (CIs) for the predictor-outcome associations were pooled using R-software, version 4.2.
Results
Sixteen studies (n = 6,079) were included in the meta-analyses. Elevated post-operative CRP was a predictor of poor OS, CSS and RFS compared with low CRP levels [HR (95%CI): 1.72 (1.32–2.25); 1.63 (1.30–2.05); 2.23 (1.44–3.47), respectively]. A unit increase in post-operative GPS predicted poor OS [HR (95% Cl): 1.31 (1.14–1.51)]. Moreover, a unit increase in post-operative mGPS was associated with poor OS and CSS [HR (95% Cl): 1.93 (1.37–2.72); 3.16 (1.48–6.76), respectively].
Conclusion
Post-operative CRP-based inflammatory biomarkers have a significant prognostic role for patients with CRC. Prognostic value of these easy-to-obtain routine measurements thereby seem to outperform most of the much more complex blood- or tissue-based predictors in the current focus of multi-omics-based research. Future studies should validate our findings, establish optimal time for biomarker assessment and determine clinically useful cut-off values of these biomarkers for post-operative risk-stratification and treatment-response monitoring.
Determination of phenotypic stability of quantitative morphological features and economic value characteristics of sweet potato tubers (Ipomoea batatas L.)
Authors: Semenenko S. V. , Leshchuk N. V. , Orlenko N. S. , Symonenko N. V. , Pavliuk N. V. 
Published: March 2023

Purpose. To justify the use of the Lewis phenotypic stabi­lity factor (SF) to determine the stability of the manifestation of quantitative and economic value characteristics of national varieties of sweet potato (Ipomoea batatas L.).
Methods. Field research on the comprehensive assessment of new sweet potato varieties was carried out in 2021–2022 at the Institute of Vegetable and Melon of the NAAS (Kharkiv Region). Phenological observations and biometric measurements of plants were carried out, as well as recording of meteorological data during the growing season, in particular during interphase periods of the culture. The stability of the studied traits was determined by finding the limit values of their manifestation (Xmax and Xmin) and further calculating the Levis phenotypic stability factor (SF).
Results. The use of the Levis phenotypic stability factor (SF) made it possible to determine the stability of the manifestation of morphological features of sweet potato varieties (I. batatas), in particular, the quantitative characteristics of tubers: their number under the bush for the variety ‘Admiral’ is 5.3 pcs., for ‘Slobozhanskyi rubin’ – 3.7 pcs.; the average weight of the tuber is 254 and 283 g, respectively. The trait “sweet potato tuber shape index” ensured stability with a coefficient of 0.98 (‘Admiral’) and 1.03 (‘Slobozhanskyi rubin’). The stability of the manifestation of morphological features of sweet potato tubers was established for the varieties ‘Admiral’ and ‘Slobozhanskyi rubin’, which are common in Ukraine. They represent two maturity groups, and therefore differ in the duration of the tuber formation period. Thus, the early-ripening ‘Admiral’ has a vegetation period of 100–110 days; medium-ripening ‘Slobozhanskyi rubin’ – 110–120 days.
Conclusions. The quantitative trait of sweet potato tubers of the ‘Admiral’ variety was more stable in terms of width; ‘Slobozhanskyi rubin’ variety – in terms length. Tuber length values varied within cultivars. The shape index of sweet potato tubers as an identification feature of varieties turned out to be variably unstable; the calculated Lewis phenotypic stability factor was lower than unity for both studied varieties.
The growing factors impact the productivity of new soft winter wheat varieties
Authors: Prysiazhniuk Larysa , Khomenko Tetiana , Liashenko Svitlana , Melnyk Serhii 
Published: March 2023

Purpose. To determine the growing factors impact the economically valuable characteristics of new soft winter wheat varieties.
Methods. Field, biochemical methods, ANOVA.
Results. The influence of the growing zone, the growing season conditions and the genotype of the soft winter wheat varieties on yield, protein and gluten content were determined. The conditions of the growing zone have the greatest influence on studied varieties yield – 73%. On average, for 2020–2021, the maximum yield was obtained in the Forest-Steppe zone – 6.23–8.39 t/ha. In the Forest zone, the yield of studied soft winter wheat varieties was 5.31–7.02 t/ha. For the Steppe zone, the yield was within 5.16–6.63 t/ha. It was determined that varieties which showed low yield in the Forrest zone were characterized by higher yield in the Steppe zone. It was found that the growing zone (49%) and growing season (42%) conditions have the greatest effect on the protein content in grain of studied varieties. It was determined that variety ‘MANDARIN’ was characterized by the highest protein content in all growing zones (14.5–16.4%). In the Steppe and Forest-Steppe zones, high protein content was identified in grain of wheat varieties ‘Tata Mata’ (13.6–14.3%), ‘Eneida’ (13.6–14.3%) and ‘Novator’ (14.2 and 13.2%), in the Forest zone – in grain of varieties ‘Vahoma’ and ‘Eneida’ – 13.4% each. It was found that the growing zone conditions impacted gluten content in grain of studied wheat varieties by 64%, the influence of the growing season conditions was 28%. The effect of variety genotype on protein and gluten content was 5 and 4%, respectively. The grain of soft winter wheat varieties ‘MANDARIN’ and ‘Eneida’ contained the largest amount of gluten in all growing zones (27.7–31.8% and 27.3–30.3%). For the Steppe and Forest-Steppe zones, a high gluten content was found in grains of varieties ‘Illusion’ (28.4 and 30.8%) and ‘Tata Mata’ (27.8 and 29.8%).
Conclusions. It was found that growing zone conditions of soft winter wheat varieties (73%) and the interaction of factors zone × year (21%) impacted the yield significantly. The growing zone conditions (49 and 64%), growing season conditions (21 and 28%) and genotype of variety (5 and 4%, respectively) had a significant influence on protein and gluten content. Therefore, a significant influence of growing zone conditions on the productivity indicators of soft winter wheat determines the need to select varieties in order to obtain a high yield, taking into account the soil and climatic zone
An Insight on the Prospect of Quinazoline and Quinazolinone Derivatives
as Anti-tubercular Agents
Authors: Kushwaha Namrata , Sahu Adarsh , Mishra Jyotika , Soni Ankit , Dorwal Dhawal 
Published: March 2023

Abstract:
Multiple potential drugs have been developed based on the heterocyclic molecules for
the treatment of different symptoms. Among the existing heterocyclic molecules, quinazoline and
quinazolinone derivatives have been found to exhibit extensive pharmacological and biological
characteristics. One significant property of these molecules is their potency as anti-tubercular
agents. Thus, both quinazoline and quinazolinone derivatives are modified using different functional
groups as substituents for investigating their anti-tubercular activities. We present a summary
of the reported anti-tubercular drugs, designed using quinazoline and quinazolinone derivatives,
in this review.
The Pathogenic Roles of lncRNAs in Glioma
Authors: Moftakhar Arya , Khoshnam Seyed Esmaeil , Farzaneh Maryam 
Published: March 2023

Abstract:
Brain cancers or intracranial cancers are among the deadliest cancers in the world. The
presence of tumorigenic cancer cells in the brain and induction of poor prognosis may impact the
survival/death balance. Glioma is a type of brain tumor that begins in the glial tissue. Recently, it has
been reported that long non-coding RNAs (lncRNAs) with at least 200 nucleotides in length by targeting
DNAs, RNAs, and proteins play essential roles in several biological processes, including
growth, differentiation, and development. Recently, lncRNAs was reported to contribute to the tumorigenesis
of glioma by targeting miRNAs, other ncRNAs, and mRNAs. In this review, we focused
on the functional roles of lnRNAs in glioma.
Cardiac Multimodality Imaging in Hypertrophic Cardiomyopathy: What
to Look for and When to Image
Authors: Bukharovich Inna , Wengrofsky Perry , Akivis Yonatan 
Published: March 2023

Abstract:
Hypertrophic cardiomyopathy (HCM), now recognized as a common cardiomyopathy of
complex genomics and pathophysiology, is defined by the presence of left ventricular hypertrophy
of various morphologies and severity, significant hemodynamic consequences, and diverse phenotypic,
both structural and clinical, profiles. Advancements in cardiac multimodality imaging, including
echocardiography, cardiac magnetic resonance imaging, and cardiac computed tomography,
with and without angiography have greatly improved the diagnosis of HCM, and enable precise
measurements of cardiac mass, volume, wall thickness, function, and physiology. Multimodality
imaging provides comprehensive and complementary information and hasemerged as the bedrock
for the diagnosis, clinical assessment, serial monitoring, and sudden cardiac death risk stratification
of patients with HCM. This review highlights the role of cardiac multimodality imaging in
the modern diagnosis and management of HCM.
The Effectiveness of an eHealth Family-Based Intervention Program in Patients With Uncontrolled Type 2 Diabetes Mellitus (T2DM) in the Community Via WeChat: Randomized Controlled Trial
Authors: Feng Yuheng , Zhao Yuxi , Mao Linqi , Gu Minmin , Yuan Hong , Lu Jun , Zhang Qi , Zhao Qian , Li Xiaohong 
Published: March 2023

Background
Intervention based on family support and risk perception can enhance type 2 diabetes mellitus (T2DM) patients’ self-care activities. In addition, eHealth education is considered to improve family members’ support for patients with T2DM. However, there is little evidence from rigorously designed studies on the effectiveness of an intervention combining these approaches.

Objective
This randomized controlled trial (RCT) aimed to assess the effectiveness of an eHealth family-based health education intervention for patients with T2DM to improve their glucose control, risk perception, and self-care behaviors.

Methods
This single-center, 2-parallel-group RCT was conducted between 2019 and 2020. Overall, 228 patients were recruited from Jiading District, Shanghai, and randomly divided into intervention and control groups. The intervention group received an eHealth family intervention based on community management via WeChat, whereas the control group received usual care. The primary outcome was the glycated hemoglobin (HbA1c) level of the patients with T2DM, and the secondary outcomes were self-management behavior (general and specific diet, exercise, blood sugar testing, foot care, and smoking), risk perception (risk knowledge, personal control, worry, optimism bias, and personal risk), and family support (supportive and nonsupportive behaviors). A 2-tailed paired-sample t test was used to compare the participants at baseline and follow-up within the control and intervention groups. An analysis of covariance was used to measure the intervention effect.

Results
In total, 225 patients with T2DM were followed up for 1 year. After intervention, they had significantly lower HbA1c values (β=–.69, 95% CI –0.99 to –0.39; P<.001). They also had improved general diet (β=.60, 95% CI 0.20 to 1.00; P=.003), special diet (β=.71, 95% CI 0.34 to 1.09; P<.001), blood sugar testing (β=.50, 95% CI 0.02 to 0.98; P=.04), foot care (β=1.82, 95% CI 1.23 to 2.42; P<.001), risk knowledge (β=.89, 95% CI 0.55 to 1.24; P<.001), personal control (β=.22, 95% CI 0.12 to 0.32; P<.001), worry (β=.24, 95% CI 0.10 to 0.39; P=.001), optimism bias (β=.26, 95% CI 0.09 to 0.43; P=.003), and supportive behaviors (β=5.52, 95% CI 4.03 to 7.01; P<.001).

Conclusions
The eHealth family-based intervention improved glucose control and self-care activities among patients with T2DM by aiding the implementation of interventions to improve T2DM risk perceptions among family members. The intervention is generalizable for patients with T2DM using health management systems in community health centers.

Trial Registration
Chinese Clinical Trial Registry ChiCTR1900020736; https://www.chictr.org.cn/showprojen.aspx?proj=31214
US Adults Practicing Healthy Lifestyles Before and During COVID-19: Comparative Analysis of National Surveys
Authors: Tam Hon Lon , Chair Sek Ying , Leung Isaac Sze Him , Leung Leona Yuen Ling , Chan Alex Siu Wing 
Published: March 2023

Background
Practicing healthy lifestyles can reduce the risk to develop noncommunicable diseases and the related mortality. Studies showed that practicing healthy lifestyles could enhance disease-free life expectancy and preserve bodily functions. However, engagement in healthy lifestyle behavior was suboptimal.

Objective
This study aimed to define individuals’ lifestyle characteristics before and during COVID-19 and determine the factors associated with practicing a healthy lifestyle. This cross-sectional study was conducted using data from the 2019 and 2021 Behavioral Risk Factor Surveillance System surveys.

Methods
US individuals aged ≥18 years were interviewed via phone call. Healthy lifestyles were assessed through corresponding questions regarding the maintenance of optimal body weight, physical activity, daily consumption of at least five portions of fruits and vegetables, current smoking status, and alcohol consumption. Missing data were imputed using a package in the R statistical software. The effects of practicing a healthy lifestyle on cases without missing data and those with imputation were reported.

Results
There were 550,607 respondents (272,543 and 278,064 from 2019 and 2021, respectively) included in this analysis. The rates of practicing a healthy lifestyle were 4% (10,955/272,543) and 3.6% (10,139/278,064) in 2019 and 2021, respectively. Although 36.6% (160,629/438,693) of all 2021 respondents had missing data, the results of the logistic regression analysis for cases without missing data and those with imputation were similar. Of the cases with imputation, women (odds ratio [OR] 1.87) residing in urban areas (OR 1.24) with high education levels (OR 1.73) and good or better health status (OR 1.59) were more likely to practice healthier lifestyles than young individuals (OR 0.51-0.67) with a low household income (OR 0.74-0.78) and chronic health conditions (OR 0.48-0.74).

Conclusions
A healthy lifestyle should be strongly promoted at the community level. In particular, factors associated with a low rate of practice of healthy lifestyles should be targeted.
FABRICATION AND EVALUATION OF MOUTH-DISSOLVING FILMS OF DOMPERIDONE
Authors: MD SARFARAZ , KUMAR SUSHIL , DODDAYYA H. 
Published: March 2023

Objective: The objective of present research work was to fabricate and evaluate mouth-dissolving films of domperidone by solvent casting method using hydroxypropyl methyl cellulose as polymer for rapid release of drug.
Methods: Domperidone (DMP) is specific blocker of dopamine receptors (D2 and D3) and is widely used to treat emesis. Since domperidone solubility is less, domperidone solid dispersion (DMP SD’s) were prepared with β-cyclodextrine inclusion complexes in different ratio (1:1, 1:2, 1:3 and 1:4) by kneading method to increase the solubility. The DMP mouth dissolving films (MDF) were developed using DMP SD’s by solvent casting method. Hydroxypropyl methyl cellulose (HPMC) was used as film forming agent and glycerine was used as plasticizer. Nine formulations were fabricated and were evaluated for their various physico-mechanical properties, in vitro disintegration time and in vitro dissolution characteristics.
Results: The solid dispersion SD3 increased the solubility of drug compared to pure drug. FTIR studies revealed the integrity of the drug in its pure form in both drug-βcyclodextrine complex and finished MDF. The thickness uniformity, weight uniformity, folding endurance, surface pH and drug content of mouth dissolving films were uniform and reproducible. Formulation F1 released highest percentage of drug i.e., 100% of drug in 16 min compared to other formulations in in vitro release studies and disintegrated within 2.5 min and hence was considered as optimized formulation. The mechanism of drug release of prepared mouth dissolving films was Non-Fickian diffusion controlled kinetics.
Conclusion: Complexation by Kneading technique was found satisfactory for solid dispersion of domperidone. Solvent casting method was successfully used to obtain uniform mouth dissolving films containing drug-β cyclodextrine solid dispersion. Mouth dissolving films containing domperidone could be successfully developed and optimised.
Multidisciplinary approach to restore esthetics and function in a young patient with three consecutive impacted teeth: a case report with 18-month follow-up
Authors: Fernandes Luciana Quintanilha Pires , de Aguiar Mariana Caires Sobral , Cosendey Vera Lúcia , Capelli Junior Jonas 
Published: March 2023

ABSTRACT
This case report describes the orthodontic treatment of an 11-year-old patient with three maxillary impacted teeth on the right side. Cone-beam computed tomography showed that these teeth were close together, with the lateral incisor in a lower position, followed by the central incisor, and the canine in a more apical position. Treatment included applying traction to these teeth. A transpalatal arch was used as an anchorage device, and surgical exposure of the lateral incisor was performed for traction with an elastic chain toward the hook welded to the 0.017 × 0.025-inch steel segmented arch. Subsequently, the central incisor was surgically exposed, elastic chains were used, along with a 0.016-inch steel arch with a box loop for correcting the tooth position. The canine spontaneously began to erupt, and a 0.017 × 0.025-inch TMA segmented arch with boot loop was used to control rotation and torque of the canine during its distalization. Once these three teeth were in the arch, treatment was finished in the usual manner. For esthetic improvement, gingivoplasty was performed in the maxillary arch. Eighteen-month follow-up showed that orthodontic treatment allowed preservation of the natural teeth, the contour of gingival support, and avoidance of prosthetic rehabilitation, reestablishing the patient’s esthetics and function, with satisfactory stability.
GOOD VILLAGE GOVERNANCE: MENCEGAH FRAUD PENGELOLAAN KEUANGAN DANA DESA MELALUI APLIKASI SISKEUDES
Authors: Fajrin Farid , H. Fahrul , Suwandi Memen 
Published: March 2023

Abstrac, This study aims to determine the application of the siskeudes application as an effort to overcome and prevent potential acts of corruption and fraud in village fund management activities in realizing good village governance. This research was conducted in Barangmamase Village, South Galesong District, Takalar Regency. This research is a qualitative research with a case study approach. The results of the study indicate that the Barangmamase Village government has managed village funds properly in accordance with applicable regulations. The siskeudes application applied in the village government system is able to prevent and overcome acts of fraud or fraud caused by pressure, opportunity, rationalization, competence and arrogance. And with the implementation of the siskeudes application in the Barangmamase Village government, it is able to support the realization of a good government system towards the concept of good village governance.
Abstrak, Penelitian ini bertujuan untuk mengetahui penerapan aplikasi siskeudes sebagai upaya untuk mengatasi dan mencegah potensi perbuatan korupsi dan kecurangan terhadap kegiatan pengelolaan dana desa dalam mewujudkan good village governance. Penelitian ini dilakukan di Desa Barangmamase Kecamatan Galesong Selatan kabupaten Takalar. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Hasil penelitian menunjukkan bahwa pemerintah Desa Barangmamase telah melakukan pengelolaan dana desa dengan baik sesuai dengan aturan yang berlaku. Aplikasi siskeudes yang diterapkan dalam sistem pemerintahan desa mampu mencegah dan mengatasi tindakan fraud atau kecurangan yang disebabkan oleh faktor tekanan (pressure), kesempatan (opportunity), rasionalisasi (rationalization), keahlian (competence) dan arogansi (arrogance). Serta dengan diterapkannya aplikasi siskeudes dalam pemerintahan Desa Barangmamase mampu mendukung terwujudnya sistem pemerintahan yang baik menuju konsep good village governance.