bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bright Is Not Always Better: A Pictorial Review of Hyperechoic Malignant Breast Masses
Authors: Parashar Shivya , Arora Jyoti , Mittal Ayushi 
Published: May 2023

AbstractHyperechogenic breast lesions are a relatively rare finding at breast ultrasonography and are traditionally thought to be benign. However, hyperechogenicity on the ultrasound alone does not provide enough evidence to rule out malignancy completely. We herein reported a short series of nine cases of echogenic malignant breast lesions, which include invasive ductal carcinoma, ductal carcinoma in situ, invasive lobular carcinoma, angiosarcoma, lymphoma, and metastasis to the breast. Echogenic breast lesions should be carefully evaluated and properly categorized based on any other suspicious sonographic characteristics and must be correlated with mammographic findings and clinical history to lower the threshold for biopsy and avoid delay in diagnosis.Hyperechogenicity should not be considered as a characteristically benign feature and should not supersede the less specifically benign features of the same lesion on the other examination.
Learning, reflexivity, decision-making, and behavioral change for sustainable viticulture associated with participatory action research
Authors: Madouas Maxime , Henaux Mélanie , Delrieu Valentine , Jaugey Caroline , Teillet Emma , Perrin Mireille , Schmitt Carine , Oberheiden Marc , Schermesser Frédéric , Soustre-Gacougnolle Isabelle , Masson Jean Eugène 
Published: May 2023

AbstractDespite the abundance of compelling scientific knowledge about dramatic changes in climate, biodiversity and the environment, there is little change in human behavior. Do humans perceive and understand the gravity of the challenges at stake, or are they overwhelmed by adversity? The challenge may be in finding appropriate levers to involve stakeholders in a broader process of shared learning, while producing scientific knowledge, to overcome uncertainty, and achieving the expected collective action? In the field of viticulture, researchers, winegrowers, citizens and environmental associations have been involved in participatory action research projects, one located in Switzerland, one in Germany and two in France. All actors were involved, from the formulation of questions up to the production of knowledge, to address the issue of the negative impacts of viticulture on the environment and human health. Group workshops and individual interviews were conducted on each of the four sites, for a nine-year period. A collective workshop involving also actors outside the project was conducted, and followed by a trinational workshop bringing together actors from Swiss, German and French projects. The audio recordings and writings produced were transcribed. All texts were analyzed on the linguistic level, with textometric tools, while going back to the actors’ initial quotes. Our results suggest that during the course of projects, more sustainable viticultural practices were designed, and implemented in the vineyard, on a large scale. Also, our analysis suggests that, in parallel to changes in viticulture practices, a new vocabulary, associated with different individual and collective reasoning, emerged in the discourse of the actors involved in projects. These major changes were associated with an inventiveness that developed within and beyond the groups. Because human reasoning changed in the context of participatory action research, we suggest that such a research format could address global issues, finally reaching awaited changes.
What can mathematical modelling contribute to a sociology of quantification?
Authors: Saltelli Andrea , Puy Arnald 
Published: May 2023

AbstractSociology of quantification has spent relatively less energies investigating mathematical modelling than it has on other forms of quantification such as statistics, metrics, or algorithms based on artificial intelligence. Here we investigate whether concepts and approaches from mathematical modelling can provide sociology of quantification with nuanced tools to ensure the methodological soundness, normative adequacy and fairness of numbers. We suggest that methodological adequacy can be upheld by techniques in the field of sensitivity analysis, while normative adequacy and fairness are targeted by the different dimensions of sensitivity auditing. We also investigate in which ways modelling can inform other instances of quantification as to promote political agency.
Local government response capacity to natural disasters in the Central Highlands Provinces, Vietnam
Authors: Van Quang Nguyen , Thanh Nguyen Hai 
Published: May 2023

AbstractNatural disasters in the Central Highlands of Vietnam are increasing and therefore becoming a concern for the provincial governments. The local authorities’ recent ability to respond to natural disasters in the region is considered ineffective, as evidenced by the increasing number of deaths and economic losses. Here, we focus on presenting and analyzing the current capacity of local authorities in the Central Highlands of Vietnam to respond to natural disasters in a normal state and in transitioning to an emergency state. We also provide evidence of natural disasters that have occurred and the actions undertaken by the Central Highlands provinces over the period 2015–2021. Our analysis shows that the capacity of local authorities to respond to natural disasters in the region is not commensurate with the actual requirements, in the dry season, the drought area increases, in the rainy season floods occur more, and human losses and economic losses have not been controlled. We propose that first of all, the government needs to have a system of timely guidance documents, the coordination between relevant agencies, secondly, that civil servants working in disaster response work must be capable, thirdly, the government must there should be publicity on how to respond, four is to limit the hot growth of projects such as hydroelectric projects, five is that the government must have a long-term master plan and sixth is to pay attention to livelihoods, education level of local ethnic people. These proposals can gradually control and limit the damage caused by increasingly severe natural disasters in the Central Highlands.
Corrigendum to “Peptide backbone-copper ring structure: A molecular insight into copper-induced amyloid toxicity”
Authors: Wang 王 Jing 静 , Jiang 姜 Xiankai 先凯 , Su 苏 Xiurong 秀榕 , Zhou 周 Xingfei 星飞 , Wang 王 Yu 宇 , Wang 王 Geng 耿 , Geng 耿 Heping 和平 , Jiang 姜 Zheng 政 , Huang 黄 Fang 方 , Chen 陈 Gang 刚 , Wang 王 Chunlei 春雷 , Fang 方 Haiping 海平 
Published: May 2023

The author list originally given in Wang et al.
Chin. Phys. B 31 108702 (2022) has been amended to remove four authors, Hua Li, Bin Wu, Jun Guo and Chenqi Xu, who believe their contributions are more suitable to be credited in the acknowledgments.
Preparation of highly efficient antibacterial non-woven by facile plasma-induced graft polymerizing of DADMAC
Authors: SONG Yujie , YANG Jing , CUI Jiangzhou , ZHAO Benhua , YANG Weimin , LI Haoyi , WANG Ruixue 
Published: May 2023

Abstract
The development of surface modification technology for temperature sensitive fibers has been a huge challenge. In this work, a novel technique based on cold plasma treatment was developed for the preparation of anti-bacterial polypropylene (PP) fibers. The results showed that plasma treatment introduced a rough surface and polar groups, which acted as the anchor point and initiators for diallyldimethyl ammonium chloride (DADMAC) graft-polymerization. The fabricated PP membranes presented a high bacterial sterilization rate, as well as excellent adhesion force and washing durability. After ultrasonic treatment for 30 min, the physical coating sample had lost anti-bacterial effect, while the plasma grafted sample still showed a sterilization rate of 91.67%. This work provided a clean and novel DADMAC grafting method and it is also applicable for anti-bacterial material fabrication.
Multiple chemical warfare agent simulant decontamination by self-driven microplasma
Authors: CHEN Shubin , WANG Shiyu , ZHU Anna , WANG Ruixue 
Published: May 2023

Abstract
Low-temperature plasma is a green and high-efficiency technology for chemical warfare agent (CWA) decontamination. However, traditional plasma devices suffer from the problems of high-power composition and large power-supply size, which limit their practical applications. In this paper, a self-driven microplasma decontamination system, induced by a dielectric-dielectric rotary triboelectric nanogenerator (dd-rTENG), was innovatively proposed for the decontamination of CWA simulants. The microplasma was characterized via electrical measurements, optical emission spectra and ozone concentration detection. With an output voltage of −3460 V, the dd-rTENG can successfully excite microplasma in air. Reactive species, such as OH, O(1D), H
α
and O3 were detected. With input average power of 0.116 W, the decontamination rate of 2-chloroethyl ethyl sulfide reached 100% within 3 min of plasma treatment, while the decontamination rates of malathion and dimethyl methylphosphonate reached (65.92 ± 1.65)% and (60.88 ± 1.92)% after 7 min of plasma treatment, respectively. In addition, the decontamination rates gradually decreased with the increase in the simulant concentrations. Typical products were identified and analyzed. This study demonstrates the broad spectrum and feasibility of the dd-rTENG-microplasma for CWA elimination, which provides significant guidance for their practical applications in the future.
Predicting Seasonal Influenza Hospitalizations Using an Ensemble Super Learner: A Simulation Study
Authors: Gantenberg Jason R , McConeghy Kevin W , Howe Chanelle J , Steingrimsson Jon , van Aalst Robertus , Chit Ayman , Zullo Andrew R 
Published: May 2023

Abstract
Accurate forecasts can inform response to outbreaks. Most efforts in influenza forecasting have focused on predicting influenza-like activity, with fewer on influenza-related hospitalizations. We conducted a simulation study to evaluate a super learner’s predictions of 3 seasonal measures of influenza hospitalizations in the United States: peak hospitalization rate, peak hospitalization week, and cumulative hospitalization rate. We trained an ensemble machine learning algorithm on 15,000 simulated hospitalization curves and generated weekly predictions. We compared the performance of the ensemble (weighted combination of predictions from multiple prediction algorithms), the best-performing individual prediction algorithm, and a naive prediction (median of a simulated outcome distribution). Ensemble predictions performed similarly to the naive predictions early in the season but consistently improved as the season progressed for all prediction targets. The best-performing prediction algorithm in each week typically had similar predictive accuracy compared with the ensemble, but the specific prediction algorithm selected varied by week. An ensemble super learner improved predictions of influenza-related hospitalizations, relative to a naive prediction. Future work should examine the super learner’s performance using additional empirical data on influenza-related predictors (e.g., influenza-like illness). The algorithm should also be tailored to produce prospective probabilistic forecasts of selected prediction targets.
Activation of the TLR4-JNK but not the TLR4-ERK pathway induced by indole-3-acetic acid exerts anti-proliferative effects on Caco-2 cells
Authors: Tomii Ayame , Higa Manami , Naito Kazuma , Kurata Koichi , Kobayashi Jun , Takei Chihiro , Yuasa Kana , Koto Yoshihito , Shimizu Hidehisa 
Published: May 2023

ABSTRACT
We previously found that indole-3-acetic acid (IAA) produced from tryptophan by gut microbiota decreases the expression of tumor necrosis factor α (TNFα), which is implicated in the pathogenesis of colorectal cancer (CRC). The present study aimed to determine IAA involvement in the proliferation of CRC-derived Caco-2 cells. Cell proliferation was suppressed by IAA, whereas IAA-induced aryl hydrocarbon receptor activation had no impact. IAA activated extracellular signal-related (ERK) and c-Jun N-terminal (JNK) kinases, but not p38. Toll-like receptor 4 (TLR4) may be required to activate ERK and JNK, but only the TLR4-JNK pathway might elicit the anti-proliferative effects of IAA. Thus, IAA may be a ligand for TLR4 that contributes to inhibiting CRC cell proliferation by activating TLR4-mediated JNK. Because IAA did not induce cytotoxicity, inhibiting cell cycle progression might affect the anti-proliferative capacity of IAA. Therefore, colonic IAA accumulation might help to prevent CRC development and progression.
Wealth taxation in the Austrian Press from 2005 to 2020: a critical political economy analysis
Authors: Dammerer Quirin , Hubmann Georg , Theine Hendrik 
Published: May 2023

Abstract
This study focuses on the Austrian media coverage of wealth taxes by conducting a content analysis of all commentary pieces published in 2005–2020 by five Austrian daily newspapers. We find (i) that the majority of commentaries take a negative position towards wealth taxation, (ii) that journalists write more negative comments than guest authors do and (iii) 50 argumentative patterns in five main categories. In light of these findings, we discuss several potential drivers of the predominantly negative wealth taxation coverage: the high degree of ownership concentration by wealthy families and institutions in the Austrian newspaper market, the importance of advertising to fund newspapers and the influence of elite institutions as providers of information. Finally, we embed our findings in recent literature and illustrate similarities and differences of the German and Austrian media coverage of wealth taxation.
SnorkelPlus: A Novel Approach for Identifying Relationships Among Biomedical Entities Within Abstracts
Authors: Kumar Ashutosh , Sharaff Aakanksha 
Published: May 2023

AbstractIdentifying relationships between biomedical entities from unstructured biomedical text is a challenging task. SnorkelPlus has been proposed to provide the flexibility to extract these biomedical relations without any human effort. Our proposed model, SnorkelPlus, is aimed at finding connections between gene and disease entities. We achieved three objectives: (i) extract only gene and disease articles from NCBI’s, PubMed or PubMed central database, (ii) define reusable label functions and (iii) ensure label function accuracy using generative and discriminative models. We utilized deep learning methods to achieve label training data and achieved an AUROC of 85.60% for the generated gene and disease corpus from PubMed articles. Snorkel achieved an AUPR of 45.73%, which is +2.3% higher than the baseline model. We created a gene–disease relation database using SnorkelPlus from approximately 29 million scientific abstracts without involving annotated training datasets. Furthermore, we demonstrated the generalizability of our proposed application on abstracts of PubMed articles enriched with different gene and disease relations. In the future, we plan to design a graphical database using Neo4j.
Father absence and pubertal timing in Korean boys and girls
Authors: Susie Lee D , Semenchenko Hanna 
Published: May 2023

Abstract

Background and objectives
Pubertal timing is a key life history trait with long-term health consequences in both sexes. Evolutionary theory has guided extensive research on developmental influences, in particular growing up without a father, on earlier menarche. Far less is known whether a similar relationship exists for boys, especially beyond western contexts. We used longitudinal data from the nationally representative sample of Korean adolescents, which provided us with a unique opportunity for studying male puberty using a hitherto underutilized biomarker: age at first nocturnal ejaculation.

Methodology
We pre-registered and tested a prediction that growing up in father-absent households is associated with earlier puberty in both sexes. Large sample size (&gt;6000) allowed testing the effect of father absence, which remains relatively uncommon in Korea, while adjusting for potential confounders using Cox proportional-hazard models.

Results
Self-reported age at first nocturnal ejaculation was on average 13.8 years, falling within the range known from other societies. Unlike previous findings mostly for white girls, we did not find evidence that Korean girls in father-absent households had a younger age at menarche. Boys in father-absent households reported having their first nocturnal ejaculation 3 months earlier on average, and the difference was evident before age 14.

Conclusion and implications
The association between father absence and pubertal timing appears sex- and age-dependent, and these differences may further interact with cultural norms regarding gender roles. Our study also highlights the utility of the recalled age of first ejaculation for male puberty research, which has lagged in both evolutionary biology and medicine.
Mental health burdens among North American Asian adults living with chronic conditions: a systematic review
Authors: Islam Jessica Y , Parikh Nina S , Lappen Hope , Venkat Vandana , Nalkar Priyanka , Kapadia Farzana 
Published: May 2023

Abstract
Asians are likely to experience a high burden of chronic conditions, including, but not limited to, diabetes, cardiovascular disease, and cancer, due to differences in biologic, genetic, and environmental factors across Asian ethnic groups. A diagnosis of any chronic condition can contribute to increased mental health burdens, including depression, psychological distress, and posttraumatic stress disorder (PTSD). However, few studies have examined these comorbid conditions across distinct Asian ethnic groups—an important limitation given the differences in social, cultural, and behavioral drivers of mental health burdens within and across Asian ethnicities. To understand the disparities in mental health burdens among Asians living with a chronic health condition, we conducted a systematic literature review of relevant, peer-reviewed publication databases to identify studies reporting on mental health burdens (e.g., depression, anxiety, distress, PTSD) in distinct Asian ethnic groups in North America. Thirteen studies met the inclusion criteria for this review and collectively demonstrated a high burden of depression, psychological distress, and PTSD among Asians living with chronic conditions. Moreover, there were distinct disparities in mental health burdens across chronic conditions and across Asian ethnic groups. Despite the detrimental impact of poor mental health on chronic disease–specific outcomes, such as death and poor quality of life, few data exist that characterize mental health outcomes among Asian ethnicities living in North America with chronic conditions. Future work should prioritize estimating the national prevalence of mental health outcomes among adults with chronic conditions, by Asian ethnicities, to inform culturally tailored interventions to address this public health burden.
Bacillus subtilis small replicative plasmid collection incorporating five distinct origins of replication and compatible with Golden Gate DNA assembly
Authors: Rodd Andrew M , Jawad Abrar , Nano Francis E 
Published: May 2023

Abstract
In order to facilitate Golden Gate DNA assembly, we have constructed a collection of Bacillus subtilis replicative plasmids representing five origins of replication derived from plasmids pUB110, pE194, pWV01, pBS72, and pTH1030. The first three of these plasmids use rolling circle replication and the latter two use theta replication. All of the plasmids carry the same multiple cloning site surrounded by transcriptional terminators. The plasmids are about three kilobases in size, allowing them to be easily amplified by inverse PCR using a common set of primers to generate cloning-ready amplicons. This plasmid PCR amplification approach also facilitates a workflow that eliminates Escherichia coli as a shuttle intermediate. All of the plasmids lack a site for at least three of the type IIS restriction enzymes BbsI, BsaI, Esp3I, PaqCI, or SapI, making them compatible with Golden Gate DNA assembly. We have demonstrated the utility of the plasmids by performing Golden Gate assembly of gusA and bgaB-reporter gene fragments and in expressing plasmid-borne red fluorescent protein under the control of RNA polymerase from bacteriophage K1E.
Sebacic Acid as a Potential Age-Related Biomarker of Liver Aging: Evidence Linking Mice and Human
Authors: Huang Chen-Hua , Lee Wei-Ju , Huang Yi-Long , Tsai Ting-Fen , Chen Liang-Kung , Lin Chao-Hsiung 
Published: May 2023

Abstract
The aging process is complicated and involves diverse organ dysfunction; furthermore, the biomarkers that are able to reflect biological aging are eagerly sought after to monitor the system-wide decline associated with the aging process. To address this, we performed a metabolomics analysis using a longitudinal cohort study from Taiwan (N = 710) and established plasma metabolomic age using a machine learning algorithm. The resulting estimation of age acceleration among the older adults was found to be correlated with HOMA-insulin resistance. In addition, a sliding window analysis was used to investigate the undulating decrease in hexanoic and heptanoic acids that occurs among the older adults at different ages. A comparison of the metabolomic alterations associated with aging between humans and mice implied that ω-oxidation of medium-chain fatty acids was commonly dysregulated in older subjects. Among these fatty acids, sebacic acid, an ω-oxidation product produced by the liver, was significantly decreased in the plasma of both older humans and aged mice. Notably, an increase in the production and consumption of sebacic acid within the liver tissue of aged mice was observed, along with an elevation of pyruvate-to-lactate conversion. Taken together, our study reveals that sebacic acid and metabolites of ω-oxidation are the common aging biomarkers in both humans and mice. The further analysis suggests that sebacic acid may play an energetic role in supporting the production of acetyl-CoA during liver aging, and thus its alteration in plasma concentration potentially reflects the aging process.
Acoustic signature of impermeable barriers in porous media
Authors: González J G , Sahay P N , Müller T M 
Published: May 2023

SUMMARY
Impermeable barriers are abundant in rock formations and their delineation via seismic reflections are of prime importance. However, such barriers have received little attention in the poroelasticity literature. For this reason, we revisit the reflection–transmission problem for two porous half-spaces which are in welded contact and across which no fluid exchange is possible. We carry out this analysis in the poroelastic theory initiated by de la Cruz and Spanos (1985), which describes four waves: the fast P, fast S-, slow P and slow S waves. The fast P and S waves account for the in-phase motion in compression and shear nature, whereas the slow P and S waves are the out-of-phase motion. We find that the often times suggested notion of effective elastic scattering is not quite correct because of the generation of slow waves at the impermeable contact. The energy flux the slow waves carry is negligibly small at low frequencies when the fluid is viscously coupled to the solid frame. In contrast, slow waves carry substantial energy flux at high frequencies when the fluid is viscously decoupled. Moreover, the reflection–transmission behaviour at an impermeable contact is distinctively different when compared to that of a permeable contact, which means that, in principle, amplitudes of scattered waves can be used to identify the kind of contact. A seemingly unnoted but important result is the strong conversion scattering from a fast S wave into the slow P wave at high frequencies, which may be an alternative way to observe slow P waves in the laboratory as well as a means to characterize impermeable contacts.