bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pancreatico-jejunostomy versus pancreatico-gasrostomy after pancreatico-duodenectomy in decreasing postoperative pancreatic fistula
Authors: Shaeir Sayed Shaker , ElKordy Mohamed Atef , Sobeih Mohamed Emam , Allam Rasha Mahmoud , Hanafy Ayman 
Published: August 2023

Background
Pancreatico-duodenectomy is still the cornerstone in curating pancreatic and periampullary cancers. Many techniques for pancreatic anastomosis were described. Pancreatico-gastrostomy (PG) may be a suitable technique, especially in small pancreatic ducts where the stitching of duct to mucosa may be difficult. Still, the results of pancreatico-gastrostomy compared to pancreatico-jejunostomy (PJ) in terms of morbidity are not well studied; hence, this study was designed to investigate.

Objective
To compare pancreatico-gastrostomy versus pancreatico-jejunostomy post pancreatico-duodenectomy from points of operative techniques and characteristics, and postoperative morbidity and mortality.

Patients and methods
The Cohort study included all cases diagnosed with either pancreatic head or periampullary cancers and underwent pancreatico-duodenectomy at National Cancer Institute (NCI), Cairo University, between January 2021 and February 2023. Cases were enrolled into one of the two groups, group 1: underwent pancreatico-gastrostomy, while group 2 underwent pancreatico-jejunostomy. The two groups were compared by: Demographic characteristics, preoperative investigations results, operative, postoperative data and histopathological results of the specimens resected.

Results
Incidence of the pancreatic leak was not significantly different in both groups (17.6% versus 15.8% for PG and PJ respectively, P=0.833), operative time was shorter in a pancreatico-gastrostomy group (310, 355 min, P=0.001), Delayed gastric emptying (DGE) was less occurred in cases of pancreatico-gastrostomy (5.9%, 31.6%, P=0.006). Postoperative mortality was not different in both groups (8.8%, 2.6% for PG and PJ respectively, P=0.338).

Conclusion
Regarding the incidence of postoperative pancreatic fistula, both reconstruction methods produce comparable postoperative results. Pancreatico-gastrostomy is a good alternative technique to the standard pancreatico-jejunostomy.
Effect of Moderate Intensity Aerobic Exercise on Fertility Hormones in Male Obese Individual in Nnewi, Nigeria
Authors: Onuora Ifeoma Joy , Meludu Samuel Chukwuemeka , Dioka Chudi Emmanuel , Obi-Ezeani Chikaodili Nwando 
Published: August 2023

Context:
Obesity is a major global public health issue which could result from sedentary lifestyle and poor dieting, and consequently hormonal imbalance.

Aim:
To evaluate fertility hormones in male obese subjects, and the subsequent effect of moderate intensity aerobic exercise on these parameters after 12 weeks of intervention.

Subjects and Methods:
90 obese (48 class I and 42 class II) and 50 normal weight (control) subjects were recruited. Subsequently, 18 male obese subjects were randomly selected and subjected to a 12-week aerobic training program using a total cross bar machine, three sessions weekly, which consisted of a 10–15 min warm-up and 35–50 min total cross bar machine exercise. Blood samples were collected at baseline, 6 weeks and after 12 weeks of intervention for luteinizing hormone, follicular stimulating hormone (FSH), prolactin, testosterone, and estradiol using enzyme-linked immunoassay.

Statistical Analysis:
Statistics was done using SPSS version 23.

Results:
The mean level of testosterone and FSH was significantly lower while estradiol was significantly higher in class I and II when compared with the control (P < 0.05). On subjecting them to 12 weeks exercise, there were significant increases in FSH and testosterone and decrease in estradiol when compared with the baseline values (P < 0.05).

Conclusion:
Weight loss through moderate intensity exercise may improve the reproductive hormone profile of male obese individuals, thereby reducing rate of infertility.
A New Approach for the Management of Knee Hyperextension in Pediatric Cases
Authors: Chechani Gouri RajendraKumar , Patel Sahil 
Published: August 2023

Background:
Knee hyperextension can be a serious and disabling injury in both the athletic and general patient population. The flexible type of knee hyperextension can be controlled by either static or dynamic knee orthosis. An important aspect of patient care in knee hyperextension is the application of proper knee orthosis. Knee orthosis is a nonoperative method for the management of knee hyperextension. It is a challenging task in this new engineering field of orthotic science for the orthotist to design suitable orthosis for knee hyperextension. The modern method of orthotic technology needs changes to benefit patients with knee hyperextension to fulfill the functional need for the user. A knee orthosis should, hypothetically, allow full range of motion, except it limits where there will be orthotic constraints. This knee orthosis is a modified polypropylene knee hyperextension orthosis for nonoperative management of knee hyperextension.

Aims and Objective of the Study:
The purpose of the design is to provide a nonoperative solution to control knee hyperextension in pediatrics for the prevention of knee structures by changing the line of force.

Materials and Methods:
It is a custom-made orthosis made of polymer sheet with a hinged knee joint with thigh shell and leg shell placed in the contralateral side and provides a rigid support for the knee without hindering knee flexion with full restriction of knee hyperextension. There will be no suprapatellar protrusion like the one conventional plastic supracondylar knee orthosis.

Results:
Based on observational gait analysis, molded polypropylene knee hyperextension orthosis provides a stable gait pattern with a minute or no gait deviation from the normal gait parameters (gait parameters varies between different subjects).

Conclusions:
A technique has been proposed for the management of genu recurvatum. A theoretical and practical justification for the method has been presented, and a thorough analysis is required. The use of modified knee orthosis appears to give protection against the anterior tibial translation, thus preventing hyperextension and gives a better gait with the help of initial flexion angle.
Adverse Event Following Immunization and Relation with Blood Group Following COVID19 Vaccination among Indian Community
Authors: Pandit Niraj , Patel Nilesh 
Published: August 2023

Introduction:
In middle of the 3rd wave, COVID19 is now gradually making agent host environment balance at the world level. COVID19 vaccine is also available for the prevention of diseases. The two vaccines which are available in India till July 2021, they are COVISHIELD and Covaxin. There are various news heard about the relation of the ABO blood group and COVID19 disease. However, no study has tried to the relation of various blood groups and adverse events following immunization (AEFI).

Methods:
This was a community-based cross-sectional study. It was conducted online mode with the use of Google Forms. Study participants were Indian citizens and who took either Covishield or Covaxin as COVID19 vaccination. The pretested form was used, which consisted of various information regarding blood group of individual, vaccine, type of vaccine, doses of vaccine, side effects postvaccination, what is/are side effects and other information like do you have disease COVID19.

Results:
A total of 893 participated in the study, but out of them, 731 participants took vaccine either one or two doses. Most of the participants, 597 (87%), were from urban areas. The postCOVID19 vaccine AEFI prevalence was 69.7%. The association between ABO and Rh blood group and AEFI was not statistically significant. However, Covaxin has lesser side effects compared to COVISHIELD. Even a small group of COVID19 disease also had no association with ABO or Rh blood group.

Conclusion:
The side effects following the COVID19 vaccine are quite common. Majority were mild AEFI. There is no statistical association with blood group and postCOVID19 AEFI.
Zinc and Anthropometry in Sickle Cell Disease
Authors: Alaka Anuoluwa Abisola , Alaka Olubunmi Olayemi , Iyanda Ayobola Abolape 
Published: August 2023

Introduction:
Homozygous rather than heterozygous sickle cell disease (SCD) is considered the more severe form of the disorder. While some markers have been used successfully to distinguish between the two with respect to disease severity, the role of other markers remains either inconclusive (e.g., nitric oxide) or ambiguous (e.g., anthropometry). The objective of the study was to provide information about possible variations in anthropometry and zinc (Zn) levels among SS and SC patients in Osun State, Nigeria.

Materials and Methods:
Adult participants enrolled consisted of 34 SS hemoglobinopathy (also known as HbSS); 32 SC hemoglobinopathy (commonly referred to as HbSC) patients and 32 with HbAA as control. Serum Zn estimation was done by atomic absorption spectrophotometry. Anthropometry (body weight, standing height, body mass index [BMI], head and mid-upper-arm circumferences [MUACs]) was determined using standard procedures. Data were analyzed with analysis of variance and Pearson correlation coefficient. P < 0.05 was considered statistically significant.

Results:
All anthropometric parameters were significantly lower for SCD patients compared with control, but only body weight was significantly different when HbSS and HbSC were compared. Serum Zn status of control was higher than those of SCD patients, with HbSS values being more significantly lower than those of HBSC. Among the HbSS as well as HbSC patients, there was a positive correlation between BMI and Zn as well as between HC and MUAC.

Conclusion:
Results of the study indicate that while the Zn status of HbSS and HbSC were significantly different, most of the anthropometric parameters were not significantly different.
Factors Influencing Quality of Life after Lower Extremity Amputation
Authors: Thomas Dantis John , Rajendran C. V. 
Published: August 2023

Background:
Despite the fact that patients with critical limb ischaemia, diabetic foot, advanced malignancies and major trauma to extremities undergo lower limb amputation, the personal satisfaction or quality of life (QoL) of such patients remains inadequately portrayed. This study tried to portray which spaces' amputees consider significant in deciding their well-being related QoL.

Objective:
To study the factors influencing QoL of patients who have undergone lower extremity amputation attending the department of general surgery of a tertiary hospital and to compare the QoL of amputee population with that of general population.

Methodology:
It was a cross-sectional study. The study population included patients who underwent lower extremity amputation in the department. 110 subjects, aged above 18 years, who have undergone lower extremity amputation and who consented to take part in the study were included.

Results:
The QoL as calculated from the Physical Component Summary and Mental Component Summary scores, using short-form-36 questionnaire showed that the physical health and the mental health (MH) both were significantly low in the amputee population. It was seen that gender with female sex having a better physical health quality compared to the male sex. Gender, use of prosthetic devise, stump infections and employment status contributed to MH quality. The QoL of an individual was severely altered following amputation. Both physical and MH domains were significantly reduced in an amputee compared to the general population. Gender influenced both the mental and physical QoL, with females performing better. Use of prosthesis was seen to be significant in MH. This underscores the need for proper rehabilitation programmes.

Conclusion:
The factors recognised should be seriously addressed in order to improve the QoL of lower limb amputees.
Factors Associated with Development of Post-Operative Pancreatic Fistula
Authors: George Amal , Sajan P. , Kuruvilla Rojan , Viswanath U. V. Akshay , Augustine Jinto Thomas , Rajan Abishek , Nambiar Rajesh , Sahadevan Sajeesh , Noushif M. 
Published: August 2023

Introduction:
Post-operative pancreatic fistula (POPF) is one of the major complications of pancreaticoduodenectomy (PD), which is the procedure of choice for many peripancreatic diseases. POPF may lead to or be combined with post-pancreatectomy haemorrhage and delayed gastric emptying or abscesses and sepsis, possibly leading to subsequent shock, multiorgan failure and mortality. The study was conducted with the objective to identify the factors associated with the development of POPF following PD.

Methodology:
This was a record-based cross-sectional study done in Kerala which recorded the details of 125 patients who underwent surgery between January 2018 and January 2020. Inclusion criteria were patients admitted with pathology in and around the head of the pancreas and requiring PD. Patient characteristics, disease-related details, pre-operative morbidities, details of surgery, and post-operative details were accessed from the patient record.

Results:
The mean standard deviation age of the participants was 60 (11.2) years. There was a higher proportion of males compared to females. The underlying lesion was malignant for the majority. Nearly 90% of the participants underwent classical PD. Nearly half of the patients developed POPF of which one-third were clinically relevant. Lack of history of chronic pancreatitis and post-operative drain fluid amylase was found to be significantly associated with POPF occurrence.

Conclusion:
Lack of history of chronic pancreatitis, amount of drainage fluid and amylase level was found to be significantly associated with the presence of post-operative fistula.
A Study to Determine the Incidence of Coexisting Carcinoma In situ in Mastectomy Specimens with Invasive Breast Carcinoma
Authors: Prakash Bineesh , Mohanan P K 
Published: August 2023

Background:

In situ breast carcinoma is a pre-invasive cancer that has not breached the epithelial basement membrane. This was previously a rare but is becoming increasingly common. It may be ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS). DCIS is a precursor of invasive carcinoma, whereas LCIS is not a precursor but only a predictor of invasive carcinoma. In those with LCIS, 50% of the carcinomas occur in the contralateral breast.

Aim:
This paper aims to study the incidence of DCIS and LCIS in mastectomy specimens of invasive carcinoma breast.

Materials and Methods:
This is a subjective study of 226 patients in a tertiary care hospital over a period of 18 months. Patients with invasive breast carcinoma undergoing mastectomy were included. Patients with invasive breast carcinoma and those who have undergone any breast surgeries in the past were excluded. The histopathology reports were analysed for finding out DCIS and LCIS coexisting with invasive carcinoma of the breast.

Results:
The patients had a mean age of 56–11.025 years. 59.7% were in the 41–60-year age group. DCIS coexisted with invasive carcinoma in 28.3% (64). LCIS was absent in all cases of invasive carcinoma. Amongst those with DCIS, high-grade DCIS was found in 65.6% (42) and low-grade DCIS in 34.4% (22). Amongst the DCIS group, comedo type was present in 46.9% (30), followed by cribriform type 31.2% (20), solid type 18.8% (12) and papillary type 3.1% (2).

Conclusion:
DCIS was found to coexist with invasive carcinoma in 28.3% of cases, whereas LCIS was absent in all cases of invasive carcinoma.
Evaluation of a pharmacy emergency response conference workshop
Authors: McCourt Elizabeth , Watson Kaitlyn 
Published: August 2023

Background: The importance of pharmacists' involvement in disasters is becoming increasingly recognised in the literature. The aim of this project was to determine the effectiveness of a disaster workshop in improving pharmacy staff’s perceived capabilities to prevent, prepare for, respond to, and recover from disasters.
Methods: A disaster workshop was provided at a pharmacy conference. The workshop incorporated an evolving emergency scenario in which participants worked through activities pertaining to the prevention, preparedness, response, and recovery cycles. The attendees were invited to complete a previously validated pre-post survey assessing their perceptions of their skills and capabilities in the components of disaster management.
Results: The pre-post survey was completed by 31 attendees. After the workshop, participants' perceptions of their ability to prevent, respond to, and recover from a disaster significantly improved (p=0.004, 0.013, and 0.013, respectively).
Conclusion: This study demonstrated that a conference disaster workshop can improve the understanding and perceived disaster capabilities of health-system pharmacy personnel.
The Business Diplomacy of Mayora Indah Ltd. on The Kopiko Brand Through Export to the Philippines and Promotions on Korean Dramas
Authors: Salam Syahrul , Juned Mansur , Utami Rahmadini Agung Ayu 
Published: August 2023

Diplomacy in business is needed to make market expansion activities more effective. This step by MNCs is then referred to as business diplomacy and also benefits the state because it can simultaneously become a means of diplomacy and achieve state interests. Mayora Indah Ltd. is a giant MNC from Indonesia that can dominate the global market. The success of Mayora Indah Ltd. in filling the global market can be seen in the popularity of Kopiko as their flagship product. This article aims to determine the strategies of business diplomacy taken by Mayora Indah Ltd to achieve the company's interests successfully. This article will then review the concepts related to business diplomacy proposed by Alammar & Pauleen (2016) as a foundation for analyzing the case study. This research finds that in the core knowledge competencies, Mayora Indah Ltd. applies internal knowledge through exposure to Kdrama producers related to Kopiko, with the aim that they can understand the product that will later be aired. Meanwhile, on multi-perspective consideration, Mayora Indah Ltd. invests in manufacturing in the Philippines and buys coconut commodities for environmental scanning.
Consideraciones axiológicas en la formación académica universitaria venezolana
Authors: Rodríguez Lissirt Miguel E 
Published: August 2023

La universidad, institución de educación superior, fundamentada en la trilogía academia-investigación y extensión para la producción de conocimientos que conduzcan a la transformación social, mediante el proceso enseñanza aprendizaje aplicados en la sociedad, una vez egresados como profesionales. La universidad venezolana está concebida como una comunidad de intereses espirituales que reúne a profesores y estudiantes en la tarea de buscar la verdad y afianzar los valores trascendentales del hombre. El objetivo de este ensayo es fomentar los valores para ello, es indispensable la axiología que se orienta hacia la construcción trascendental de los principios y valores del ser humano, que inicia con el “yo” como individuo y se materializa en “nosotros” es decir, lo colectivo o sociedad. El estudio responde a la tipología de investigación cualitativa, y dentro del contexto, se ubica el paradigma interpretativo o constructivista, para la interpretación de la interacción social en la que se propone que se debe estudiar las interpretaciones y significados y ontológicamente, el investigador se relaciona con los sujetos, es decir estudiantes y profesionales de manera intersubjetiva, empleándose además como método, la fenomenología para dar sentido interpretativo de la conducta de los profesionales en su vivencia personal como colectiva, a través de la descripción y la interpretación de esas conductas; ya que este método busca descubrir el significado y sentido de las experiencias vividas de las personas. Se concluye que, la axiología como disciplina filosófica, juega un rol de relevancia en la formación académica universitaria, como elemento trascendental del individuo y de la sociedad.
Interventions to Support Participation in Play for Autistic Children and Youth (Dates of Review: 2013–2021)
Authors: Little Lauren M. , Cohen Samantha R. , Tomchek Scott , Baker Alissa , Wallisch Anna , Dean Evan 
Published: August 2023

Abstract
Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s Evidence-Based Practice Program. Each systematic review brief summarizes the evidence on a theme related to a systematic review topic. This systematic review brief presents findings to support participation in play for autistic1 children and adolescents (birth to 18 yr).
RELATO DE PESQUISA: DESENVOLVIMENTO DE UM APLICATIVO PARA DIVULGAÇÃO DE EDITAIS DE INOVAÇÃO, INOVCTE- PARTE DESCRITIVA
Authors: Santos Fabiana Arcanja dos 
Published: August 2023

Esse relato de pesquisa se refere ao desenvolvimento de uma proposta pertinente no processo de acesso às informações nas áreas de inovação, ciência, tecnologia e empreendedorismo no que tange aos sobre os editais vigentes disponíveis nas principais agências de fomento governamentais, como o CNPq, FINEP e CAPES, assim como empresas de capital aberto, como Petrobras e Eletrobras, agências de fomento baianas, como FAPESB, Coelba e Chesf, e a empresa privada Sebrae. ampliando o fluxo de informações nesse contexto. objetivando nessa oportunidade apresentar as telas e parte dos conteúdos do aplicativo (INOVCTE), ferramenta desenvolvida para proporcionar a comunidade acadêmica desde estudantes, professores e demais interessados, a possibilidade de busca facilitada de editais de forma centralizada em um banco de dados, bem como demonstrar o resultado positivo da pesquisa de intenção de utilização, via formulário Survey Monkey na perspectiva de sinalizar o elevado interesse dos participantes da pesquisa na promoção desse aplicativo representando uma amostra relevante para impulsionar novas práticas nesse âmbito.
Problema. Insuficiência de plataformas que promova acesso a disseminação seletiva de informação reunida, para editais da inovação, ciência, tecnologia e empreendedorismo, gratuito. Objetivo. Possibilitar amplo acesso a promoção de editais de inovação, ciência, tecnologia e empreendedorismo visando estabelecer conexão entre interessados e instituições promotoras desses editais de financiamento e parcerias em único ambiente e demonstrar o resultado positivo da pesquisa de intenção de utilização do App, via formulário survey monkey, bem como apresentar as telas e parte dos conteúdos do aplicativo. Método. pesquisa quali quantitativa, utilizando prospecção na web, em bases governamentais e público privadas para identificar a ocorrência e disponibilidade de suas APIS (código que permite a transmissão de dados) para proceder agrupamento automático ou por inteligência artificial, desenvolvimento de aplicativo e formulário de pesquisa de intenção de uso. Resultados. Foram encontrados no período somente serviços pagos para divulgação seletiva de informação em financiamento e parcerias; as instituições não puderam contribuir com suas APIS. O delineamento da pesquisa se configurou nesse sentido, desenvolver um aplicativo para sanar prioritariamente o déficit de promoção de editais de algumas instituições público privadas. Nesse sentido foi desenvolvido um App com certificação INPI, publicado na Play store para Android e publicado artigo sobre a pesquisa. Conclusão. Tendo desenvolvido o aplicativo INOVCTE na plataforma kodular, foi procedido de forma manual a captação dos informes de editais de inovação ciência, tecnologia e empreendedorismo, bem como inserido no sistema web, sites de notícias referente a inovações diversas implementadas diariamente. Oxalá haja mais disponibilidade das instituições em contribuir com disponibilização de seus dados públicos para pesquisas.