bluuebunny/crossref_metadata_2025_split huggingface dataset:
ADAPTIVE CONTROL ELECTRICITY CONSUMPTION IN LOCAL MICROENERGY SYSTEM WITH POLYGENERATION BASED ON CLUSTERING OF A CONDITIONAL DYNAMIC TARIFF
Authors: Kaplun Viktor , Makarevych Svitlana , Petrenko Andrii , Kruhliak Hennadii , Kulybaba Yevhenii 
Published: June 2023

The paper is devoted the increasing the efficiency to use of traditional and renewable sources in microenergy systems. The development of combined power supply systems of local objects with the stochastic nature generation of renewable sources has led to a number of fundamental problems.
It is associated with the lack of a decision-making system regarding the ratio of power sources of electricity and the coordination of their generation levels with the electricity consumption schedule at the stage of designing such microgrids. The development of microenergy systems with polygeneration is conditioned by the possibility of technical and information support for the formation of the energy balance of local objects to minimize the costs of their electricity supply.
By applying elements of inductive system-analytical technologies, an approach to solving the problem of modeling dynamic scenarios of energy management in local microgrids with polygeneration based on determining the cost of electricity and adaptive coordination of the electricity consumption schedule in real time is proposed.
On the basis of statistical data, modeling was carried out and daily graphs of changes in the current cost of electricity with half-hour discreteness of the calculation were obtained, and the clustering procedure of the conditional dynamic tariff was showed.
The results can be applied in the evaluation of electricity pricing in microgrid energy management systems or the development of control systems for Smart grids with renewable sources.
EXPERIMENTAL WOUND HEALING ASPECTS OF JASMINUM GRANDIFLORUM LINN: A PRECLINICAL STUDY
Authors: Mittal Arun , Satish Sardana , Anima Pandey 
Published: June 2023

Background: Jasminum grandiflorum is an important shrub of family Oleaceae and ancient literature mentions its various medicinal uses especially its efficacy in wound healing. To substantiate its traditional claim the present study was conceived.
Materials and Methods: Preliminary wound healing activity of successive extracts of leaves was assessed by measuring wound contraction using excision wound model and the detailed study of most potent extract was evaluated by measuring wound contraction, epithelialization period, hydroxyproline content, tissue breaking strength and histopathology parameters by excision and incision wound models.
The antioxidant activity was determined by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. The agar well-diffusion method and minimum inhibitory concentration (MIC) was used to established antimicrobial efficacy.
Results: The results show that successive ethanolic extract of the leaves exhibited promising wound healing, antioxidant and antimicrobial properties.
Conclusion: From results; it is concluded that its traditional use for the treatment of wound and in microbial infection is justified.
QUANTIFICATION AND ANTIBACTERIAL ACTIVITY OF FLAVONOIDS IN COFFEE SAMPLES
Authors: Ullah Riaz , Ahmad Shabir , Atiq Aimen , Hussain Hidayat , Rehman Najeeb ur , AbdElsalam Naser M. , Adnan Muhammad 
Published: June 2023

Background: Flavonoids are the phenolic substances widely found in fruits, vegetables, grains, bark, roots, stems, flowers, tea and coffee.
Methodology: In the current study quantity of flavonoids and antibacterial activities were determined in different coffee samples namely Nescafe
classic, Nescafe gold, Nescafe martina, original, creamy and cafe soluvel by using standard methodology available in literature.
Results: Nescafe original and gold showed highest content of flavonoid while cafe soluvel showed lowest content of flavonoid. Cafe soluvel, gold
and classic showed good antibacterial activities.
Conclusion: This study showed that coffee is good source of flavonoids and had excellent antibacterial potential.
DIURETIC ACTIVITY OF CAROB (CERATONIA SILIQUA L.) HONEY: COMPARISON WITH FUROSEMIDE
Authors: El-Haskoury Redouan , Zizi Soumaya , Touzani Soumaya , Al-waili Noori , Al-Ghamdi Ahmad , Lyoussi Badiaa 
Published: June 2023

Background: Honey has wide range of biological activities. It has effect on renal function, and urinary nitric oxide and prostaglandins level.
The present study was conducted to evaluate diuretic potential of carob honey, collected from Morocco, in normal rats and the results were
compared with use of furosemide.
Materials and methods: Adult male Wister rats weighing between 230 and 278 g were used. The animals were divided into three groups; group
1 received oral administration of distilled water (10 ml/kg BW), and served as control group, group 2 received oral administration of furosemide
(10 mg/kg BW), and group 3 was treated with oral administration of carob honey (100 mg/kg BW). Urine volume, and urine and plasma sodium
and potassium were measured after single dose of the interventions and after daily administrations of the interventions.
Results: After the single dose of carob honey, urine output was significantly increased at all time intervals (1-6 hrs and at 24 hrs after
administration). The daily dose of carob honey for nine days significantly increased urine volume as compared to control group. Carob honey
increased urinary levels of sodium and potassium, and did not cause hypokalemia, while furosemide increased urinary sodium and potassium
and caused hypokalemia.
Conclusion: Carob honey has diuretic, natriuretic and kaliuretic activity without side effects of hypokalemia that was observed with use of
furosemide.
PROLONGED HEATING OF HONEY INCREASES ITS ANTIOXIDANT POTENTIAL BUT DECREASES ITS ANTIMICROBIAL ACTIVITY
Authors: Jahan Nusrat , Islam Md. Asiful , Alam Fahmida , Gan Siew Hua , Khalil Md. Ibrahim 
Published: June 2023

Background: Honey is renowned for its antioxidant, antimicrobial and medicinal properties. It is typically heated and filtered during processing
to avoid crystallization. However, few studies have reported its heating effect and the antioxidant and antimicrobial activities of honey.
Materials and Methods: In this study, honey samples were collected from eight different honey-producing sites in Bangladesh and heated to
50ºC, 70ºC and 90ºC for 12 hours, while the antioxidant potentials and antimicrobial properties of the heated samples were compared with those
of the unheated samples. Antimicrobial properties were investigated against one Gram-positive and eight Gram-negative bacteria. Other
physicochemical and biochemical properties were also determined.
Results: Interestingly, there was a proportionate increase in the amount of antioxidant compounds (phenolics and flavonoids) as well as
antioxidant potentials proportional with the amount of heat introduced, whereas the antimicrobial properties of the honey samples were reduced
with increasing heat.
Conclusion: In conclusion, though prolonged heat treatment of honey can increase its antioxidant potential, antimicrobial activities are
compromised.
IN VITRO ANTI-INFLAMMATORY AND FREE RADICAL SCAVENGING ACTIVITIES OF CRUDE SAPONINS EXTRACTED FROM ALBUCA BRACTEATA JACQ. BULB.
Authors: Odeyemi Samuel , Afolayan Anthony , Bradley Graeme 
Published: June 2023

Background: Albuca bracteata is a medicinal plant traditionally used in the management of diabetes mellitus in the Eastern Cape of South Africa. The purpose of this study was to evaluate the antioxidant and anti-inflammatory activities of saponins extracted from the bulb of Albuca bracteata and compared with the crude methanolic extract.
Methods: In vitro antioxidant activity was determined using free radical scavenging assays such as DPPH, ABTS and NO2. The anti-inflammatory potential was carried out using inhibition of protein denaturation of egg albumin as a model of anti-inflammatory capacity.
Results: Both the crude methanolic extract and saponins showed inhibition of DPPH, ABTS and NO2 scavenging activity. However, the free radical scavenging activity of isolated saponin compared favourably with Rutin and BHT. The crude methanolic extract showed higher inhibition percentage of protein denaturation compared with the saponins at the concentration investigated.
Conclusion: This study indicates that saponin from Albuca bracteata bulb possess potent anti-inflammatory activity and is also a good source of natural antioxidant.
THE EFFECT OF SAFFRON (ITS ACTIVE CONSTITUENT, CROCIN) ON THE CARDIOVASCULAR COMPLICATION AND DYSLIPIDEMIA IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Authors: Altinoz Eyup , Taskin Emre , Oner Zulal , Elbe Hulya , Arslan Belkis Atasever 
Published: June 2023

Background: Diabetes mellitus (DM) causes serious complications such as coronary heart disease, atherosclerosis, nephropathy, retinopathy
and neuropathy.
Materials and Methods: Rats were randomly divided into three groups each containing 10 rats; control group, DM group; DM+crocin group.
Normal saline was administered in the control and DM groups, and crocin was administered in DM+crocin group at a dose of 20 mg/kg bw/day
for 21 days. Trunk blood and the hearth tissue were collected for histopathological and biochemical examination.
Results: DM led to increment of MDA levels (p
EFFECTS OF HIBISCUS SABDARIFFA L. CONSUMPTION DURING PREGNANCY ON BIOCHEMICAL PARAMETERS AND LITTER BIRTH WEIGHT IN RATS
Authors: Eghosa Iyare E. , Charles Ezeh O. , Thomas Nubilla , Ifeoma Orizu A. 
Published: June 2023

Background: Extracts of Hibiscus sabdariffa L. (HS; family: Malvaceae) are widely believed in folk medicine to be effective in the treatment of
a variety of ailments. In Nigeria, anecdotal reports by women who consume HS during pregnancy suggest that they consume it because of the
folkloric belief that it makes them “feel lighter”. This study aimed to investigate the effect of maternal consumption of HS during pregnancy on
litter birth weight and the functional integrity of the liver of pregnant rats.
Materials and Methods: Thirty-six rats aged twelve to fourteen weeks were used. On day 1 of pregnancy, the rats were randomly assigned to
three groups. Group A were given tap water, group B were given 0.6g/100ml while group C were given 1.8g/100ml of the extract. On day 18 of
pregnancy, blood samples were taken for determination of Serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate
transaminase (SGPT), alkaline phosphatase, urea and creatinine.
Results: Gestational length, litter size and birth weights were recorded at delivery. HS consumption did not affect (P>0.05) SGOT level but
increased (P
EVALUATION OF TOPICAL ANTIMICROBIAL OINTMENT FORMULATIONS OF ESSENTIAL OIL OF LIPPIA MULTIFLORA MOLDENKE
Authors: Oladimeji Francis Abiodun , Akinkunmi Ezekiel Olugbenga , Raheem Abiola Ibrahim , Abiodun Gbemisola Omotola , Bankole Victor Oloruntoba 
Published: June 2023

Background: Essential oil of Lippia multiflora (lippia oil) has been reported to possess antibacterial and antifungal activities. This study was aimed at developing an effective topical formulation of the oil for the treatment of skin infections.
Materials and Methods: Lippia oil was extracted from leaves of L. multiflora by hydrodistillation. Different concentrations of the oil were incorporated into six different ointment bases. Tween 80 was incorporated at different concentrations into ointments containing 10 %w/w lippia oil; a concentration at which minimum antimicrobial activity was observed in the ointment bases. The viscosity, spreadability and stability of the formulations were determined. Antimicrobial activities of lippia oil in the formulations were determined against select bacteria and fungi using the agar diffusion assay method. 10 %w/w salicylic acid formulations were used as reference products.
Results: Incorporation of lippia oil into the ointment bases led to reduction in their viscosity with increase in spreadability. None of the formulations showed antimicrobial activity at lippia oil content ≤ 5 %w/w. Inclusion of Tween 80 in the formulations significantly increased the antimicrobial activities of the oil (P < 0.5). The antimicrobial activities of 10 %w/w lippia oil formulated in absorption bases containing 6 %w/w Tween 80 was significantly higher (P < 0.5) than those formulated in hydrophobic bases. Lippia oil ointment formulations showed greater antimicrobial activities than salicylic acid ointments. Two of the lippia oil ointment formulations bled when subjected to centrifugal force.
Conclusion: Ointment formulations of lippia oil (10 %w/w) in absorption base (Hydrous Wool fat Ointment BP or Simple Ointment BP) containing 6 %w/w Tween 80 were found stable and very effective in inhibiting growth of selected pathogens implicated in skin infections.
Publication Trends in Research on Mental Health and Mental Illness in Orthopaedic Surgery
Authors: Schmerler Jessica , Solon Lorenzo , Harris Andrew B. , Best Matthew J. , LaPorte Dawn 
Published: June 2023

Background:
Mental health conditions affect tens of millions of Americans. In recent years, particularly with the advent of the coronavirus disease 2019 pandemic, there has been a burst of interest in mental health and mental illness among orthopaedic surgical patients. The mental health of orthopaedic surgeons themselves has also come into focus, with high reported rates of burnout and depression. The aim of this article was to evaluate trends in publication on mental health and mental illness in orthopaedic surgery.

Methods:
Web of Science and PubMed were queried to conduct a systematic review. Studies that discussed orthopaedic surgery and mental illnesses or mental health topics over 2001 to 2022 were included. Publications were analyzed by article-, author-, and topic-level characteristics.

Results:
A total of 416 studies were analyzed after application of inclusion and exclusion criteria. Publication volume increased dramatically, demonstrating quadratic growth over 2001 to 2022 (p < 0.001). Eighty-eight percent of studies focused on patients and 10% on surgeons, with studies about patients more likely to focus on mental illness and those about surgeons more likely to focus on mental health (p < 0.001). Twenty percent of publications had a female senior author, and 5 authors collectively accounted for 10% of all publications. Eight journals published more than 10 publications, accounting for 35% of all publications. The most productive subspecialties were arthroplasty (135, 30%), general orthopaedics (87, 21%), and spine (69, 17%). Mental illnesses that were least represented included schizophrenia, bipolar disorder, eating disorders, attention-deficit/hyperactivity disorder, and personality disorders (1% or less of total publications each).

Conclusion:
This analysis showed a dramatically increasing trend in publications on mental health and mental illness in orthopaedic surgery. A high concentration of publications came from a subset of journals and senior authors, and women were overrepresented as senior authors relative to their representation in the field. The results of this analysis identified gaps in the literature, including underrepresented subspecialties, understudied mental illnesses, and study of orthopaedic surgeon mental health, and thus highlighted areas for future investigation.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Carbonate Sedimentation in High-Mineralized Lake Bolshoi Bagan (South of West Siberia): Dependence on Holocene Climate Changes
Authors: Solotchin P.A. , Solotchina E.P. , Maltsev A.E. , Leonova G.A. , Krivonogov S.K. , Zhdanova A.N. , Danilenko I.V. 
Published: June 2023

Abstract
––We present the results of comprehensive studies of Holocene bottom sediments from the shallow hypersaline (mineralization up to 282 g/L) Lake Bolshoi Bagan, located in the East Baraba lowland (south of Western Siberia). The research methods include X-ray diffractometry (XRD), IR spectroscopy, laser granulometry, scanning electron microscopy, elemental analysis of sediments and pore water, radiocarbon (14C AMS) dating. It has been found that during the Holocene an intensive authigenic mineral formation took place in the lake basin; gypsum, halite and carbonates of calcite-dolomite series dominate among the newly formed mineral phases. Mg-calcites with different Mg contents, excess-Ca dolomites, aragonite and occasionally Mg-siderite have been found in the assemblage of carbonate minerals by mathematical modeling of complex XRD patterns. Mineralogical and crystallochemical studies, supplemented by the results of geochemical analyses, allowed us to identify four stages of the evolution of Lake Bolshoi Bagan in the Holocene, due to regional climate variations. The boundaries of the stages in general correspond to the boundaries of the climatostratigraphic phases by the Blytt–Sernander system: Stage I (the end of the Boreal) – the lake formation, humid climate; Stage II (Atlantic) – climate aridization, shallowing of the lake; Stage III (Subboreal) – unstable climate, frequent change of conditions; Stage IV (Subatlantic) – moderately cool and dry climate.
Estimating Time and Frequency under Imperfect Channel Knowledge using ECM and SAGE Algorithms in Multi-relay Cooperative Networks
Authors: CHENGUTTUVAN EZHILAZHAGAN , KARUPPIAH LAKSHMI PRABHA , K SAKTHISUDHAN 
Published: June 2023

Abstract

The OFDM system is popular due to its broadband capabilities, but because it employs the multi-carrier concept, synchronization issues may arise. These errors are caused by the incompatibility of the transmitted and received signals. The performance of multiple relay cooperative systems is assessed in this study using receiver compensation and estimation of Multicarrier Frequency Offsets (MCFO) and Multiple Timing Offsets (MTO). To demonstrate improved bit error rate (BER) performance, MCFOs and MTOs should be treated with less computational complexity. At the receiver end, the Maximum Likelihood (ML) approach is used to decode data and estimate offsets. The ML approach estimates using the ECM and SAGE algorithms. In terms of BER and SNR after estimation, the SAGE algorithm outperforms the ECM approach. A performance analysis of the estimated time and carrier frequency offsets was performed using the ECM and SAGE algorithms. Furthermore, the statistical percentage difference demonstrates that the maximum probability strategy for compensating the CFO and TO is effective.
Accuracy and generalizability of machine learning models for adolescent suicide prediction with longitudinal clinical records
Authors: Zang Chengxi , Hou Yu , Jin Jun , Sacco Shane , Chen Kun , Aseltine Robert , Wang Fei 
Published: June 2023

Abstract

Machine Learning (ML) models trained from real-world data (RWD) have demonstrated promise in predicting suicide attempts in adolescents. However, their cross-data performance and transportability for suicide prediction are largely unknown, hindering the clinical adoption of these ML models. We developed different ML suicide prediction models based on RWD collected in different contexts (inpatient, outpatient, etc.) with varying purposes (e.g., administrative claims and electronic health records), compare their cross-data performance, and evaluate their transportability. The data used was from the All-Payer Claims Database (APCD) and Hospital Inpatient Discharge Database (HIDD) in Connecticut as well as Electronic Health Records (EHR) data provided by Kansas Health Information Network (KHIN). From three datasets collected in different settings (inpatient, outpatient, etc.) and purposes (e.g., administrative claims and electronic health records), we included 285,320 patients among whom we identified 3389 (1.2%) suicide attempters. 66.0% of the suicide attempters were female. Different machine learning models (regularized logistic regression, gradient boosting machine, long-short term memory neural network) were evaluated on the local datasets and transported datasets. Significant and comparable decreases in the transfer performance compared to the local performance of all three ML models were observed, with the decline in performance reducing average AUC by up to 7.7%, reducing average sensitivity by up to 16%, and PPV by up to 2% at the 90% specificity level, and reducing sensitivity by up to 20% and PPV by up to 5% at the 95% specificity level. The similarity of behavior across these modeling approaches strengthens the validity of our results. The commonality and heterogeneity of predictors learned across populations were compared. These results indicate that no matter how well ML suicide models performed with their source data, their performance when transporting these models to new datasets is limited. However, the transported models did identify additional new cases. Our analyses could facilitate the development of suicide prediction models with better performance and generalizability.
Global conservation status of the jawed vertebrate Tree of Life
Authors: Gumbs Rikki , Scott Oenone , Bates Ryan , Böhm Monika , Forest Félix , Gray Claudia , Hoffmann Michael , Kane Daniel , Low Christopher , Pearse Will , Pipins Sebastian , Tapley Benjamin , Turvey Samuel , Jetz Walter , Owen Nisha , Rosindell James 
Published: June 2023

Abstract
Human-driven extinction threatens entire lineages across the Tree of Life. Here we assess the conservation status of jawed vertebrate evolutionary history, using three policy-relevant approaches. First, we calculate an index of threat to overall evolutionary history, showing that we expect to lose 86-150 billion years (11-19%) of jawed vertebrate evolutionary history over the next 50-500 years. Second, we rank jawed vertebrate species by their EDGE scores to identify the best opportunities for species-focused conservation of evolutionary history. Third, we assess the conservation status of jawed vertebrate families. We found that species within monotypic families are more likely to be threatened and more likely to be in decline than other species. We provide a baseline for the status of families at risk of extinction to catalyse conservation action. This work continues a trend of highlighting neglected groups—such as testudines, crocodylians, amphibians and chondrichthyans—as conservation priorities from a phylogenetic perspective.