bluuebunny/crossref_metadata_2025_split huggingface dataset:
The board gender composition and cost of debt: Empirical evidence from Jordan
Authors: Mansour Marwan , Al Zobi Mo'taz , Saleh Mohammed W. A. , Al‐Nohood Saddam , Marei Ahmad 
Published: September 2023

AbstractThe present research aims to examine the influences of board gender composition on debt costs and its significance to Jordanian creditors: mainly banks, using agency and resource dependence theories. A sample of 113 non‐financial Jordanian firms listed on the Amman Stock Exchange (ASE) from 2010 to 2019 was utilised to explore the impact of board gender on the cost of debt financing through panel regression analysis. To tackle endogeneity concerns, we employ a two‐step system generalised method of moments estimator. The findings discovered that more female directors on firm boards generated economic benefits for non‐financial sectors, which achieved an average 0.75% cut‐off interest rate incurred by lenders compared to the counterparts with fewer female directors. Our findings are still robust to endogeneity concerns. The findings offered valuable insights for academics, shareholders, firms, and regulators. Shareholders are required to provide more pressure on firms to enhance gender equality. Firms should adjust board gender composition via the inclusion of more female directors while regulators should develop guidelines, such as a minimum female quota in promoting more females to the board. The finding generalisability is limited to developing markets with similar settings. This study bridged a vital gap in the governance literature on the nexus between board gender composition and debt costs in Jordanian contexts where no minimum gender quota exists.
President's Page
Authors: Caidi Nadia 
Published: September 2023

EDITOR'S SUMMARYChange and renewal characterize ASIS&T with new initiatives, programs and management developments to better serve the membership. The first ASIS&T Regional Meeting, held April 15, 2016, at Rutgers University offered stimulating panels and showed student leaders' dedication to building the Association. Members' suggestions have led to featuring short video presentations by doctoral students on the ASIS&T website and explorations into professional concerns and accreditation reforms. The ASIS&T Information Architecture and Research Data Access and Preservation Summits thrive, rallying dynamic and important communities within the profession. ASIS&T management changes include the plan to hire a communications officer to boost the Association's visibility and responsiveness to members and the pending retirement of executive director Dick Hill after nearly 30 years of service. Preparations for the 2016 Annual Meeting, to be held in Copenhagen, Denmark, are in full swing, including opportunities to bid Dick thanks and farewell.
The DataQ Story
Authors: Johnson Andrew 
Published: September 2023

EDITOR'S SUMMARYLongstanding frustration about the single‐purpose use of valuable data led author Andrew Johnson to a career in librarianship, a focus on scientific data curation and, ultimately, creation with colleague Megan Bresnahan of the DataQ project. Johnson's concerns about research data management being a silo within the profession were overcome with the realization that many librarians, especially those at smaller institutions, saw the need for effective curation but felt untrained and unequipped to deal with it. DataQ was established as a service and resource for library personnel to ask questions on data curation and learn through expanding group knowledge. Launched in August 2015, the project draws on a team of 15 editors and additional support members and has been widely and positively received. Funding by the Institute of Museum and Library Services, the Greater Western Library Alliance and others will help expand the effort to provide an important service to the library community.
Analysis of clinicopathological characteristics and prognostic factors of early‐stage human epidermal growth factor receptor 2 (HER2)‐low breast cancer: Compared with HER2‐0 breast cancer
Authors: Wu Qian , Yang Fan , Liu YinHua , Zhang Hong , Zhang Shuang , Xin Ling , Xu Ling 
Published: September 2023

AbstractPurposeTo investigate the clinicopathological characteristics and prognostic factors of early‐stage breast cancer (EBC) with human epidermal growth factor receptor 2 (HER2)‐low expression.MethodsThe clinicopathological data and follow‐up information of EBC patients with HER2‐low and HER2‐0 expression treated at the Breast Disease Center of Peking University First Hospital from January 2014 to December 2017 were analyzed. The prognosis between HER2‐low and HER2‐0 expression groups and with different hormone receptor (HR) expression were compared by statistics. Meanwhile, the expression of Ki67, androgen receptor (AR), TOPIIa, P53, PTEN, and CK5/6 were also analyzed with the HER2‐low expression and prognosis.ResultsRetrospectively analyzed 1253 cases of EBC, including 583 (46.5%) cases of HER2‐low breast cancer (BC) and 366 (29.2%) HER2‐0 BC cases. Among the HER2‐low BC patients, 487 (83.5%) were HR‐positive, while 96 (16.5%) were HR‐negative. Among the HER2‐0 BC patients, 265 (72.4%) were HR‐positive, while 101 (27.6%) were HR‐negative. Median follow‐up time was 53 months. The 5‐year disease‐free survival of HER2‐low BC patients was 90.2% (95% confidence interval [CI]: 87.2–93.1), and the 5‐year overall survival was 95.4% (95% CI: 93.3–97.6). Cox regression analysis showed that T stage, lymphovascular invasion, and/or perineural invasion were prognostic factors of HER2‐low BC patients. However, the 5‐year disease‐free survival and overall survival of patients in the HER2‐low and HER2‐0 groups were not significantly different in all patients, but a tendency of better prognosis in HER2‐low group was seen in HR‐negative tumors.ConclusionHER2‐low EBC patients accounted for 46.5% of the patient population. T stage, lymphovascular invasion, and/or perineural invasion were factors affecting the prognosis of BC patients with low HER2 expression. No significant difference in prognosis was noted between HER2‐low and HER2‐0 EBC patients. But in HR‐negative tumors, a tendency of better prognosis was seen in HER2‐low versus HER2‐0.
Clinical approach to a child with hemophagocytic lymphohistiocytosis and bilateral optic nerve head infiltration: A case report and brief literature review
Authors: Shekarchian Farid , Abadi Mitra Karimi Amir , Shariati Mehrdad Motamed 
Published: September 2023

Key Clinical MessageInfiltrative optic neuropathy in hemophagocytic lymphohistiocytosis is rare but could potentially lead to visual loss. Cytomegalovirus (CMV) optic neuritis, drug toxicity, and CNS involvement with increased intracranial pressure (ICP) are differential diagnoses that have to be considered.AbstractIn this report, we introduced a known case of hemophagocytic lymphohistiocytosis (HLH) with progressive visual loss due to bilateral optic nerve head (ONH) involvement. A 9‐year‐old boy with a history of HLH from 6 months ago was referred to the ophthalmic emergency department with a complaint of painless progressive blurred vision in his right eye. The fundus examination found an optic disc swelling and peripapillary hemorrhage in the right eye. The left fundus examination showed a mild ONH blurred margin. Systemic evaluations including brain and orbital MRI with gadolinium enhancement and CSF analysis showed optic nerve and brain involvement with tumoral cells. Despite systemic chemotherapy with etoposide, the disease had a progressive course so in the last follow‐up visit, fundus examination revealed disc swelling, retinal edema, and epiretinal hemorrhage in both eyes and visual acuity deteriorated to no light perception and counting fingers in the right and left eye, respectively. ONH involvement in HLH is rare but could be sight‐threatening. Differential diagnoses that should be investigated include neoplastic infiltrative optic neuropathy, cytomegalovirus (CMV) optic neuritis, drug toxicity, and CNS involvement with increased intracranial pressure (ICP).
Exploration of the Copper‐Catalyzed Sydnone and Sydnonimine‐Alkyne Cycloaddition Reactions by High‐Throughput Experimentation
Authors: Louis Manon , Force Guillaume , D'Anfray Timothée , Bourgeat Emma , Romero Eugénie , Thuéry Pierre , Audisio Davide , Sallustrau Antoine , Taran Frédéric 
Published: September 2023

AbstractThe reactivity of sydnones and sydnonimines toward terminal alkynes under copper catalysis has been explored using High‐Throughput‐Experimentation. A large panel of ligands and reaction conditions have been tested to optimize the copper‐catalyzed sydnone click reaction discovered by our group ten years ago. This screening approach led to the identification of new ligands, which boosted the catalytic properties of copper and allowed the discovery of a new copper‐catalyzed click‐and‐release reaction involving sydnonimines. This reaction allowed chemoselective ligation of terminal alkynes with sydnonimines and, simultaneously, the release of an isocyanate fragment molecule that can be used for further transformations.
Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms
Authors: Fang Yuan , He Xia , Peng Ai , Yang Yi qi , Xiang Jin 
Published: September 2023

AbstractTo investigate the association between esomeprazole pharmacokinetics and CYP2C19 gene polymorphisms in a cohort of 95 healthy Chinese participants. A cohort of 95 participants was assembled and stratified into 2 distinct groups, receiving either 20 or 40 mg of esomeprazole through oral administration. The subjects encompassed 17 poor metabolizers, 47 intermediate metabolizers, and 31 rapid metabolizers, and their genotypes were ascertained using the polymerase chain reaction–restriction fragment length polymorphism technique. Esomeprazole plasma concentrations were quantified employing a high‐performance liquid chromatography–ultraviolet method. Pharmacokinetic parameters were computed via Phoenix WinNonlin 6.1 software, while SPSS 26.0 facilitated statistical analysis to contrast the pharmacokinetics and the CYP2C19 genotypes. In the aftermath of administering 20 or 40 mg esomeprazole, marked differences were discerned between terminal elimination half‐life, maximum concentration/dose, and area under the plasma concentration–time curve from time zero to infinity/dose of esomeprazole (P < .05), with the exception of time to maximum concentration. The findings of this investigation signify a significant association between esomeprazole metabolism and CYP2C19 gene polymorphisms. There were no unprecedented adverse events documented subsequent to the administration of 20 and 40 mg esomeprazole dosages. Esomeprazole has manifested promising safety and tolerability profiles in pertinent clinical trials.
Morality's role in the Black Sheep Effect: When and why ingroup members are judged more harshly than outgroup members for the same transgression
Authors: Tang Simone , Shepherd Steven , Kay Aaron C. 
Published: September 2023

AbstractWhen and why might someone judge an ingroup transgressor more harshly than an outgroup transgressor? Taking a social functionalist perspective, we argue that morality is central to this phenomenon–the Black Sheep Effect–and that it is driven by social cohesion concerns. Using mediation and moderation methods across our studies, we find that people judge ingroup (vs. outgroup) transgressors more harshly because of concerns regarding ingroup social cohesion (Studies 1a–4). We also find that ingroup derogation is stronger for moral transgressions than weak or non‐moral transgressions (Studies 2 and 3). Throughout our studies, we address alternative explanations, including moral relativism, naïve realism, moral parochialism and belief in a just world. Our work speaks to the emerging contention around the reliability of the Black Sheep Effect by noting when and why it surfaces.
When and why does economic inequality predict prosocial behaviour? Examining the role of interpersonal trust among different targets
Authors: Lin Jing , Li Wenqi , Guo Zhen , Kou Yu 
Published: September 2023

AbstractPrevious research suggests that economic inequality has caused a wide range of negative societal impacts. However, little is known about how economic inequality influences prosocial behaviour as a socioecological environment determinant. In five studies (N = 62,342), we examined whether economic inequality reduces prosocial behaviour by decreasing interpersonal trust and the moderation role of interpersonal targets. Studies 1, 2a, and 2b showed that interpersonal trust mediated the negative relationship between perceived economic inequality and prosocial behaviour. In Study 3, we used data from the World Values Survey to explore the relation between inequality and trust and found that it was moderated by the closeness of trust targets. In Study 4, we demonstrated that economic inequality only reduced trust and prosocial behaviour towards strangers, but not among friends and family. Taken together, the current research shed light on how economic inequality undermines trust and negatively impacts prosocial behaviour among different targets.
Prediction of daily tourism volume based on maximum correlation minimum redundancy feature selection and long short‐term memory network
Authors: Yin Ming , Lu Feiya , Zhuo Xingxuan , Yao Wangzi , Liu Jialong , Jiang Jijiao 
Published: September 2023

AbstractHistorical tourism volume, search engine data, and weather calendar data have close causal relationship with daily tourism volume. However, when used in the prediction of daily tourism volume, the feature variables of the huge and complex search engine data do not have strong independence. These repetitive and highly relevant data must be analyzed and selected; otherwise, they will increase the training burden of neural network and reduce the prediction effect. This study proposes a daily tourism volume prediction model, maximum correlation minimum redundancy feature selection and long short‐term memory, on the basis of feature selection and deep learning. Firstly, the multivariate high‐dimensional features, including search engine data and weather factors, are selected to identify the key influencing factors. Secondly, the deep neural network is used to make a multistep forward rolling prediction of daily tourism volume. Results show that keywords of famous scenic spots, weather, historical tourism volume, and tourism strategies in the search engine data significantly improve the prediction accuracy of daily tourism volume. The proposed maximum correlation minimum redundancy feature selection and long short‐term memory model performs better than other models, such as autoregressive integrated moving average, multiple regression, support vector machine, and long short‐term memory.
Joint modeling of forced vital capacity measures with time to onset of polycythemia among chronic obstructive pulmonary outpatients follows‐up: A case of University of Gondar Referral Hospital
Authors: Kassa Yoseph , Melese Dessie , Asmare Anteneh , Workneh Gashu 
Published: September 2023

AbstractBackground and AimsChronic obstructive pulmonary disease (COPD) causes airflow obstruction and respiratory problems. Thus, the main objective of this study was to determine the risk factors for the progression of COPD using longitudinally measured forced vital capacity with time to onset of polycythemia outpatients follow‐up.MethodsA retrospective study design was used to gather the related data on longitudinal change of forced vital capacity and time to onset of polycythemia from the medical charts. The joint model consists of a longitudinal submodel for the change of forced vital capacity and a survival submodel for the time to onset of polycythemia of chronic obstructive pulmonary patients.ResultsFrom the total of 266 patient's estimated value of forced vital capacity of chronic obstructive pulmonary patients was 74.45 years with a standard deviation of 8.59. The estimated value of the association parameter was −0.006, which indicates that the lower value for a forced vital capacity measure was associated with the higher risk of polycythemia and vice versa “Based on the joint model analysis found that the predictor smoking, comorbidities, marital status, weight, and HIV” jointly affected the two responses, which are change of forced vital capacity and time to onset of polycythemia among chronic obstructive pulmonary patients.ConclusionThe overall performance of separate and joint models, joint modeling of longitudinal measures with the time‐to‐event outcome was the best model due to smaller standard errors and statistical significance of both the association parameters.
Prevalence, molecular characterization, and clinical features of human bocavirus in children under 5 years of age with acute gastroenteritis admitted to a specialized children's hospital in Iran: A cross‐sectional study
Authors: Kachooei Atefeh , Karbalaie Niya Mohammad Hadi , Khales Pegah , Sabaei Milad , Fard Soheil Rahmani , Hamidzade Malihe , Tavakoli Ahmad 
Published: September 2023

AbstractBackground and AimsAlthough some reports have confirmed the role of human bocavirus (HBoV) in respiratory infections, the importance of this virus in causing acute gastroenteritis has not yet been proven. This study aimed to determine the molecular prevalence of HBoV in children under 5 years old with gastroenteritis and to compare the clinical symptoms of HBoV‐positive and ‐negative gastroenteritis cases.MethodsA total of 100 stool samples were collected from children with gastroenteritis hospitalized in a pediatric hospital in Tehran, Iran. Demographic and clinical data were collected from patients' medical records. Viral genomic DNA was extracted from stool samples and amplified using the PCR assay. Finally, sequencing was used to determine the genotype of HBoV.ResultsThe HBoV genome was detected in 14 samples (14%). The highest prevalence of HBoV was observed in the age range of 24–60 months (n = 5; 35.7%); However, no statistically significant relationship was observed between the prevalence of HBoV and age groups (p = 0.09). Nine (64.3%) and 5 (35.7%) HBoV‐positive cases were boys and girls, respectively (p = 0.45). Fever, vomiting, and heartache were seen in 5 (35.7%), 3 (21.4%), and 1 (7.1%) HBoV‐positive patients, respectively. Overall, no significant difference was observed in any of the investigated clinical manifestations between patients positive or negative for HBoV. Five HBoV‐positive samples were subjected to sequencing and all five sequenced samples were genotype 3.ConclusionHBoV infections can be considered a risk factor for causing at least a portion of acute gastroenteritis cases in children under 5 years of age.
Exploring the challenges of men who married to adolescent girls in Western Iran: A qualitative study
Authors: Yoosefi lebni Javad , Ziapour Arash , Fazeli Zahra , Saki Mandana , Ahmadi Ahmad , Mehedi Nafiul 
Published: September 2023

AbstractBackground and AimsMen face many challenges in their lives with adolescent girls that need to be identified. No research has been conducted in this field in Iran. This research aimed to explore the challenges of men married to adolescent girls in western Iran using a qualitative approach.MethodsThis research was conducted using qualitative methods and a conventional content analysis approach. Participants were 28 men in western Iran who had the experience of marrying girls under 18 years of age. Semi‐structured interviews were used both face‐to‐face and over the phone to collect data. Also, snowballing and purposeful sampling were used to select the participants. The data were also analysed using Granheim and Lundman's approach.ResultsFrom the data analysis, 1 category, 9 subcategories, and 103 primary codes were obtained. The main category was lack of empathy and consensus, which includes the subcategories of sexual dissatisfaction, girls' dependence on the family, inability to fulfill the roles of a wife, not being understood in life, remaining in the world of childhood, emotional divorce, limiting progress and preventing the achievement of goals, betrayal, and chaotic life.ConclusionYoung couples problems can be solved by measures such as giving sex education and teaching skills necessary for married life, such as problem solving skills and anger control, to adolescent men and girls, as well as training families on how to properly support adolescent couples.
PCAOB inspection deficiencies and audit fees
Authors: Alam Pervaiz , Cheng Yang , Rickett Laura K. , Skomra Justyna 
Published: September 2023

AbstractThis study aims to extend research on the effect of PCAOB inspections on audit firm behavior by examining generally accepted auditing standards (GAAS) and generally accepted accounting principles (GAAP) type PCAOB inspection deficiencies, separately, to reveal the differential effects on audit fees in subsequent years. We empirically examine the audit fees of 98,393 client firm‐year observations for auditors who received a PCAOB inspection report during 2004–2021 via multivariate regression analyses. We find that GAAS (GAAP) deficiencies are associated with higher (lower) audit fees in the years following the reported deficiency. Our results suggest that the PCAOB inspection process modifies audit firm behavior when GAAS deficiencies are reported leading to the firm charging higher audit fees to defray the costs of addressing the deficiencies, but due to the severity of GAAP deficiencies that are identified, audit firms are willing to negotiate lower fees to retain the client. Our results are primarily driven by annually inspected audit firms. These results suggest that auditors respond to GAAS and GAAP PCAOB inspection deficiencies differently. The results of our study are useful to regulators and policymakers, such as the SEC and the PCAOB, in understanding how auditors respond to PCAOB inspection deficiencies and their due diligence to correct those deficiencies. PCAOB inspections are intended to evaluate compliance with accounting and auditing standards to improve audit quality and our study helps to extend the research to date which has not yet clearly demonstrated whether or not this has been accomplished.
Used paper tissues for pathogen identification in acute respiratory infection
Authors: Rector Annabel , Bloemen Mandy , Van Ranst Marc , Wollants Elke 
Published: September 2023

AbstractDuring the Belgian winter and spring season 2022–2023, we investigated the potential of used paper tissue (UPT) as a noninvasive sampling method for the diagnosis of acute respiratory infections. Screening for respiratory pathogens was done using an in‐house developed respiratory panel for simultaneous detection of 22 respiratory viruses and seven nonviral pathogens. The method allowed the identification and typing of respiratory pathogens in symptomatic individuals, as well as in collective samples taken at a community level. Pathogens that were identified in nasal swabs could also be detected in concurrent UPT from the same patient. In all cases that tested positive on an antigen‐detection rapid diagnostic test, the corresponding virus could be detected in UPT. The collection of UPT could be useful in epidemiological surveillance of severe acute respiratory syndrome coronavirus 2 and other coronaviruses, as well as other respiratory pathogens such as influenzavirus, respiratory syncytial virus, entero/rhinoviruses including EV‐D68, parainfluenzaviruses, and Streptococcus pneumoniae. Multiple respiratory pathogens could be detected in UPTs of collectivities, confirming its applicability for community testing. This is especially interesting for screening in nursing homes, centers for the disabled, schools or other settings were taking nasal or nasopharyngeal samples is cumbersome.