bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uncovering the spatiotemporal evolution of the service industry based on geo-big-data- a case study on the bath industry in China
Authors: Zhao Bingyu , Li Jingzhong , Xue Bing 
Published: February 2023

AbstractThe bath industry has multiple attributes, such as economic, health, and cultural communication. Therefore, exploring this industry's spatial pattern evolution is crucial to forming a healthy and balanced development model. Based on POI (Points of Interest) and population migration data, this paper uses spatial statistics and radial basis function neural network to explore the spatial pattern evolution and influencing factors of the bath industry in mainland China. The results show that: (1) The bath industry presents a strong development pattern in the north, south-northeast, and east-northwest regions and weak development in the rest of the country. As a result, the spatial development of new bath space is more malleable. (2) The input of bathing culture has a guiding role in developing the bath industry. The growth of market demand and related industries has a specific influence on the development of the bath industry. (3) Improving the bath industry's adaptability, integration, and service level are feasible to ensure healthy and balanced development. (4) Bathhouses should improve their service system and risk management control during the pandemic.
The Use and Challenges of Spatial Data in Archaeology
Authors: Klehm Carla 
Published: February 2023

OverviewSpatial data, under the broader umbrella of digital data, is becoming increasingly integral to all stages of archaeological research design and dissemination. As archaeologists lean toward reuse and interoperability, with ethics on their minds, how to treat spatial data is of particular importance. This is because of the complexities involved at every life-cycle stage, from collection to publication, including black box issues that may be taken for granted, and because the size of spatial data can lead to archiving difficulties. Here, the “DIY” momentum of increasingly accessible spatial methods such as photogrammetry and handheld lidar is examined alongside forthcoming changes in publication policies that will impact the United States in particular, framed around a conversation about best practices and a call for more comprehensive training for the archaeological community. At its heart, this special issue seeks to realize the potential of increasingly digitized—and increasingly large amounts of—archaeological data. Within cultural resource management, this means anticipating utilization of data through widespread standardization, among many interrelated activities. A desire to enhance the utility of archaeological data has distinct resonances with the use of spatial data in archaeology, as do some wider challenges that the archaeological community faces moving forward.
The authors of our own lives: the limitations of the behavioural justification for paternalism
Authors: Oliver Adam 
Published: February 2023

AbstractIn this article, the confidence that has been placed in hard and, in particular, soft paternalistic measures in the field of behavioural public policy is questioned. The four purported limitations of human reasoning – i.e. limited imagination, willpower, objectivity and technical ability – are considered, but ultimately it is concluded that these are insufficient justifications for paternalistic intervention, for two principal-related reasons. First, it is impossible for a policy maker to discern what people desire for their own lives, and second, so long as they are not harming others, people ought to be free to pursue their own desires. The vision for the future of behavioural public policy proposed here is thus consistent with classical liberal, and in particular, Millian thought: i.e. aim to educate people on the pros and cons of their actions and inactions so that they are better equipped to live the lives they wish to lead but do not interfere directly in guiding them towards any particular end.
The Biomedical Entrepreneurship Skills Development Program for the Advancement of Research Translation: Foundations of Biomedical Startups course, metrics, and impact
Authors: Schweickart Tucker , Hill-Whilton Zachary , Chitale Sadhana , Cobos Daniel , Gilon-Yanai Michal , Achuonjei Joy , Vizgan Gabriel , Gillespie Colleen , Gold-von Simson Gabrielle 
Published: February 2023

Abstract

Background/Objective:
A growing number of biomedical doctoral graduates are entering the biotechnology and industry workforce, though most lack training in business practice. Entrepreneurs can benefit from venture creation and commercialization training that is largely absent from standard biomedical educational curricula. The NYU Biomedical Entrepreneurship Educational Program (BEEP) seeks to fill this training gap to prepare and motivate biomedical entrepreneurs to develop an entrepreneurial skill set, thus accelerating the pace of innovation in technology and business ventures.

Methods:
The NYU BEEP Model was developed and implemented with funding from NIDDK and NCATS. The program consists of a core introductory course, topic-based interdisciplinary workshops, venture challenges, on-line modules, and mentorship from experts. Here, we evaluate the efficacy of the core, introductory course, “Foundations of Biomedical Startups,” through the use of pre/post-course surveys and free-response answers.

Results:
After 2 years, 153 participants (26% doctoral students, 23% post-doctoral PhDs, 20% faculty, 16% research staff, 15% other) have completed the course. Evaluation data show self-assessed knowledge gain in all domains. The percentage of students rating themselves as either “competent” or “on the way to being an expert” in all areas was significantly higher post-course (P < 0.05). In each content area, the percentages of participants rating themselves as “very interested” increased post-course. 95% of those surveyed reported the course met its objectives, and 95% reported a higher likelihood of pursuing commercialization of discoveries post-course.

Conclusion:
NYU BEEP can serve as a model to develop similar curricula/programs to enhance entrepreneurial activity of early-stage researchers.
Virtual Aunting and Public Health Emergencies: A Novel Approach to Sharing Public Health Guidance
Authors: Ottley Amanda , Stone Courtney , Henry Marlyn , Weber Bridget , Jackson Tamaraleah , Ondieki Michael 
Published: February 2023

Abstract
Effective communication with the public is essential during health emergencies. As evident during the coronavirus disease 2019 (COVID-19) pandemic, the lack of effective public health communication with equity-deserving groups has contributed to higher morbidity and mortality than the non-racialized community. This concept paper will describe a grassroots community effort to provide culturally safe public health information to the East African community in Toronto at the beginning of the pandemic. Community members collaborated with The LAM Sisterhood to create a virtual aunt, Auntie Betty, and record voice notes with essential public health guidance in Swahili and Kinyarwanda. This manner of communicating with the East African community was well-received and has shown great potential as a tool to support effective communication efforts during public health emergencies that disproportionately impact Black and equity-deserving communities.
Obtaining molecular hydrogen from water radiolysis in the nano-SiO
2
(d = 20 nm)/H
2
O system under the influence of γ-quanta
Authors: Jafarov Y. D. , Bashirova S. M. , Mardanov I. J. , Imanova Gunel T. 
Published: February 2023

Abstract
Under the influence of γ-quanta (60Co, P = 9.276 rad/s, T = 300 K), the amount, formation rate, and radiation-chemical yield of molecular hydrogen obtained from the radiolysis process that changes the mass of water (m = 0.0001 ÷ 0.8 g) have been defined in the created nano-SiO2/H2O system with m = 0.2 g mass and d = 20 nm particle size. It was determined that the radiation-chemical yield of molecular hydrogen obtained from the water radiolysis process in the nano-SiO2/H2O system created by the adsorption of water on the nanoparticle surface had a low value. In systems created with the addition of water, the radiation-chemical yield of molecular hydrogen obtained from its radiolysis increased in direct proportion to the water mass. This proves that due to ionizing rays, the yield of electrons emitted from the nanoparticle surface into the water and solvated there increases. Therefore, the radiation-chemical yield of molecular hydrogen is higher than that of the adsorbed system.
Suppressing small-scale self-focusing of high-power femtosecond pulses
Authors: Martyanov Mikhail , Ginzburg Vladislav , Balakin Alexey , Skobelev Sergey , Silin Dmitry , Kochetkov Anton , Yakovlev Ivan , Kuzmin Alexey , Mironov Sergey , Shaikin Ilya , Stukachev Sergey , Shaykin Andrey , Khazanov Efim , Litvak Alexander 
Published: February 2023

Abstract
It was shown experimentally that for a 65-fs 17-J pulse, the effect of filamentation instability, also known as small-scale self-focusing, is much weaker than that predicted by stationary and nonstationary theoretical models for high B-integral values. Although this discrepancy has been left unexplained at the moment, in practice no signs of filamentation may allow a breakthrough in nonlinear pulse post-compression at high laser energy.
A ranching economic analysis of ventenata (Ventenata dubia) control in northeast Wyoming
Authors: Hart Marshall , Ritten John , Mealor Brian A. 
Published: February 2023

AbstractInvasive species pose a threat to the livelihoods of many people living on rangelands of the western United States. Invasive species impact many ecosystem goods and services of the areas they invade and represent one of the largest causes of habitat degradation. On private ranches, economic analyses often find that conservation practices, such as invasive species control, are not economically viable, in contrast to what is found at the landscape scale. In northeast Wyoming, ventenata [Ventenata dubia (Leers) Coss.] is a relatively new invader in the Great Plains ecoregion that threatens forage production on ranches. Our objective was to explore the economic costs of V. dubia for two options available to a ranch operation: purchasing extra hay to offset losses in forage and controlling V. dubia with herbicide. Using a partial budget analysis, we compare these two options in three invasion scenarios using a range of forage utilization rates and discount rates. Controlling V. dubia with herbicide was a cheaper option compared with purchasing additional hay in many cases. In fact, at 50% utilization, it is cheaper to control V. dubia in all of our scenarios at all discount rates given our assumptions. For lower grazing utilization rates, it becomes cheaper to purchase hay in some cases other than in our worst-case invasion scenario. In these cases, coordination among ranchers is needed to effectively control V. dubia. There are many ranch-specific differences that may make a different option more feasible, and we did not explore options of reducing herd sizes. However, our results suggest that controlling V. dubia can be an economically viable option under certain circumstances. Additional assistance in the form of a cost-share program, and facilitation of coordination is needed to overcome the difficulties of private management of invasive species.
Toward a Nation Defined by State: Tattooed Loyalty and the Evolution of Yue Fei's (1103–1142) Image from the Song to the Present
Authors: Du Yue 
Published: February 2023

AbstractThis article discusses how the legendary general Yue Fei (1103–1142) and his legacy have been perceived and appropriated in Chinese history. Twentieth-century historians approached Yue's career by highlighting the tension between his dedication to the nation (baoguo) and his personal loyalty (jinzhong) to Emperor Gaozong (1107–1187) of the Song. I argue that for Yue Fei himself and those who wrote about him in late imperial China, Yue's guo, from which he derived his political identity and toward which he devoted his service, meant first and foremost the Song dynastic state. The pushing and pulling of multivalent themes of loyalty and state service in the “historic assessment” of Yue Fei since the turn of the twentieth century speak to the complexities embedded in different Chinese governments’ navigation of ethnic and class politics in their pursuit of a new national identity for China.
The emergence of bubble-induced scaling in thermal spectra in turbulence
Authors: Dung On-Yu , Waasdorp Pim , Sun Chao , Lohse Detlef , Huisman Sander G. 
Published: February 2023

We report on the modification of the spectrum of a passive scalar inside a turbulent flow by the injection of large bubbles. Although the spectral modification through bubbles is well known and well analysed for the velocity fluctuations, little is known on how bubbles change the fluctuations of an approximately passive scalar, in our case temperature. Here we uncover the thermal spectral scaling behaviour of a turbulent multiphase thermal mixing layer. The development of a

$-3$

spectral scaling is triggered. By injecting large bubbles (

${Re}_{{bub}} = {O}(10^2)$

) with gas volume fractions

$\alpha$

up to 5 %. For these bubbly flows, the

$-5/3$

scaling is still observed at intermediate frequencies for low

$\alpha$

but becomes less pronounced when

$\alpha$

further increases and it is followed by a steeper

$-3$

slope for larger frequencies. This

$-3$

scaling range extends with increasing gas volume fraction. The

$-3$

scaling exponent coincides with the typical energy spectral scaling for the velocity fluctuations in high-Reynolds-number bubbly flows. We identify the frequency scale of the transition from the

$-5/3$

scaling to the

$-3$

scaling and show how it depends on the gas volume fraction.
Cocaine-use disorder and childhood maltreatment are associated with the activation of neutrophils and increased inflammation
Authors: Funchal Giselle A. , Schuch Jaqueline B. , Zaparte Aline , Sanvicente-Vieira Breno , Viola Thiago W. , Grassi-Oliveira Rodrigo , Bauer Moisés E. 
Published: February 2023

AbstractBackground:Cocaine-use disorder (CUD) has been associated with early life adversity and activated cellular immune responses. Women are most vulnerable to complications from chronic substance disorders, generally presenting an intense feeling of abstinence and consuming significant drug amounts. Here, we investigated neutrophil functional activities in CUD, including the formation of neutrophil extracellular traps (NETs) and related intracellular signalling. We also investigated the role of early life stress in inflammatory profiles.Methods:Blood samples, clinical data, and history of childhood abuse or neglect were collected at the onset of detoxification treatment of 41 female individuals with CUD and 31 healthy controls (HCs). Plasma cytokines, neutrophil phagocytosis, NETs, intracellular reactive oxygen species (ROS) generation, and phosphorylated protein kinase B (Akt) and mitogen-activated protein kinases (MAPK)s were assessed by flow cytometry.Results:CUD subjects had higher scores of childhood trauma than controls. Increased plasma cytokines (TNF-α, IL-1β, IL-6, IL-8, IL-12, and IL-10), neutrophil phagocytosis, and production of NETs were reported in CUD subjects as compared to HC. Neutrophils of CUD subjects also produced high levels of intracellular ROS and had more activated Akt and MAPKs (p38/ERK), which are essential signalling pathways involved in cell survival and NETs production. Childhood trauma scores were significantly associated with neutrophil activation and peripheral inflammation.Conclusion:Our study reinforces that smoked cocaine and early life stress activate neutrophils in an inflammatory environment.
A single dose of cocaine raises SV2A density in hippocampus of adolescent rats
Authors: Rossi Rachele , Bærentzen Simone Larsen , Thomsen Majken B. , Real Caroline C. , Wegener Gregers , Grassi-Oliveira Rodrigo , Gjedde Albert , Landau Anne M. 
Published: February 2023

AbstractObjectiveCocaine is a highly addictive psychostimulant that affects synaptic activity with structural and functional adaptations of neurons. The transmembrane synaptic vesicle glycoprotein 2A (SV2A) of pre-synaptic vesicles is commonly used to measure synaptic density, as a novel approach to the detection of synaptic changes. We do not know if a single dose of cocaine suffices to affect pre-synaptic SV2A density, especially during adolescence when synapses undergo intense maturation. Here, we explored potential changes of pre-synaptic SV2A density in target brain areas associated with the cocaine-induced boost of dopaminergic neurotransmission, specifically testing if the effects would last after the return of dopamine levels to baseline.Methods:We administered cocaine (20 mg/kg i.p.) or saline to rats in early adolescence, tested their activity levels and removed the brains 1 hour and 7 days after injection. To evaluate immediate and lasting effects, we did autoradiography with [3H]UCB-J, a specific tracer for SV2A, in medial prefrontal cortex, striatum, nucleus accumbens, amygdala, and dorsal and ventral areas of hippocampus. We also measured the striatal binding of [3H]GBR-12935 to test cocaine’s occupancy of the dopamine transporter at both times of study.Results:We found a significant increase of [3H]UCB-J binding in the dorsal and ventral sections of hippocampus 7 days after the cocaine administration compared to saline-injected rats, but no differences 1 hour after the injection. The [3H]GBR-12935 binding remained unchanged at both times.Conclusion:Cocaine provoked lasting changes of hippocampal synaptic SV2A density after a single exposure during adolescence
Building a precision medicine infrastructure at a national level: The Swedish experience
Authors: Edsjö Anders , Lindstrand Anna , Gisselsson David , Mölling Paula , Friedman Mikaela , Cavelier Lucia , Johansson Maria , Ehrencrona Hans , Fagerqvist Therese , Strid Tobias , Lovmar Lovisa , Jacobsson Bo , Johansson Åsa , Engstrand Lars , Wheelock Craig E. , Sikora Per , Wirta Valtteri , Fioretos Thoas , Rosenquist Richard ,   Genomic Medicine Sweden (GMS)
Published: February 2023

Abstract
Precision medicine has the potential to transform healthcare by moving from one-size-fits-all to personalised treatment and care. This transition has been greatly facilitated through new high-throughput sequencing technologies that can provide the unique molecular profile of each individual patient, along with the rapid development of targeted therapies directed to the Achilles heels of each disease. To implement precision medicine approaches in healthcare, many countries have adopted national strategies and initiated genomic/precision medicine initiatives to provide equal access to all citizens. In other countries, such as Sweden, this has proven more difficult due to regionally organised healthcare. Using a bottom-up approach, key stakeholders from academia, healthcare, industry and patient organisations joined forces and formed Genomic Medicine Sweden (GMS), a national infrastructure for the implementation of precision medicine across the country. To achieve this, Genomic Medicine Centres have been established to provide regionally distributed genomic services, and a national informatics infrastructure has been built to allow secure data handling and sharing. GMS has a broad scope focusing on rare diseases, cancer, pharmacogenomics, infectious diseases and complex diseases, while also providing expertise in informatics, ethical and legal issues, health economy, industry collaboration and education. In this review, we summarise our experience in building a national infrastructure for precision medicine. We also provide key examples how precision medicine already has been successfully implemented within our focus areas. Finally, we bring up challenges and opportunities associated with precision medicine implementation, the importance of international collaboration, as well as the future perspective in the field of precision medicine.
PILOT-WAVE HYDRODYNAMICS: QUANTISATION OF PARTIAL INTEGRABILITY FROM A NONLINEAR INTEGRO-DIFFERENTIAL EQUATION OF THE SECOND ORDER
Authors: DAY JAMES 
Published: February 2023

AbstractVertically vibrating a liquid bath may allow a self-propelled wave-particle entity to move on its free surface. The horizontal dynamics of this walking droplet, under the constraint of an external drag force, can be described adequately by an integro-differential trajectory equation. For a sinusoidal wave field, this equation is equivalent to a closed three-dimensional system of nonlinear ODEs. We explicitly define a stability boundary for the system and a quantised criterion for its partial integrability in the meromorphic category.
Molluscs along a salinity gradient in a hypersaline coastal lagoon, southern Gulf of Mexico
Authors: Suárez-Mozo Nancy Yolimar , Papiol Vanesa , Enriquez Cecilia , Brenner Mark , Simões Nuno 
Published: February 2023

Abstract
Molluscs are a diverse phylum in coastal lagoons because the numerous taxa collectively display broad ranges of optima and tolerance with respect to ambient conditions. We report on the taxonomic composition, habitat preferences and feeding guilds of molluscs from Río Lagartos coastal lagoon, Mexico. Molluscs were collected in the rainy season (September/October 2017), during the winter (Nortes) season (February 2018) and at the end of the warm, dry season (May 2018). Samples were taken using a Ponar dredge, a cylindrical PVC core barrel, or a beach seine. We studied the abiotic characteristics (sediment grain-size distributions, submersed aquatic vegetation abundance and salinity) to explore assemblage differences across the broad salinity gradient that characterizes the system (~30–78 PSU). Molluscs were represented by 39 species, 34 genera, 23 families and two classes. Stenohaline species were more numerous overall than euryhaline species, but their occurrence in samples was low (<20% of the samples). Stenohaline taxa lived primarily in environments characterized by marine salinity, and few were found under hypersaline conditions. We collected a smaller number of species than did studies carried out in the lagoon >35 years ago. Species accumulation curves revealed that the full species richness was not captured in our study. Euhaline environments displayed greater mollusc species richness and had a larger proportion of amount (mass) of submersed aquatic vegetation. In the hypersaline environments, species richness may be favoured by the lower dominance of sands. Suspension feeders were the most diverse group in both the euhaline and hyperhaline environments.
Can panpsychism solve thorny theological problems?
Authors: Miller Tim B. , Oord Thomas Jay 
Published: February 2023

AbstractJoanna Leidenhag has written a ground-breaking book arguing that the concept of panpsychism can solve several problems facing present-day humans. It can motivate greater commitment to concern for earth's diverse environments and the life forms that inhabit them. And it can solve theological problems connected with human consciousness, notably, how consciousness and matter coexist and interact. This article summarizes and comments on Leidenhag's arguments, then suggests several paths forward for those inspired by Leidenhag's ideas and arguments who wish to explore them and related notions in greater depth.