bluuebunny/crossref_metadata_2025_split huggingface dataset:
Further Considerations on the Question of Deleuze’s Neo-Leibnizianism
Authors: Geretto Mattia 
Published: January 2023

La relation de Deleuze avec l’histoire de la philosophie et avec Leibniz en particulier est une relation qui se développe pendant plus de vingt ans et nous permet de situer la question du néo-leibnizisme dans le cadre plus large du « style », du « vol » et de la manière de faire de la philosophie par Deleuze. Cette contribution souligne que le terme néo-leibnizianisme est inventé selon Deleuze pour indiquer sa propre philosophie. La réinterprétation de la métaphysique de Leibniz par Deleuze – une réinterprétation également influencée par des auteurs tels que Simondon, Péguy et Ruyer –, est analysée à travers le remaniement de certains concepts clés tels que les « singularités pré-individuelles », la « vice-diction », la théorie de l’événement et le « chaosmos ». Enfin, cette réinterprétation se cristallise dans une ontologie de « capture » et « inclusion », qui remplacent les variables leibniziennes de « clôture » et de « sélection ». Dans le seul plan transcendantal admis par Deleuze, la monade et l’événement même deviennent « un passage de Dieu », ouvrant la voie d’une manière originale dans la même ontologie de Deleuze à une suggestive et problématique théologique de l’immanence.
Instabilité énonciative et hiérarchie des valeurs dans l’ Histoire véritable : l’effet-personnage et la projection sensorielle chez Montesquieu
Authors: Magnot-Ogilvy Florence 
Published: January 2023

L’article part de la narrativité problématique de l’ Histoire véritable qui partage avec les Lettres persanes une discontinuité narrative et une multiplicité des points de vue. L’instabilité énonciative de ces deux textes y fragilise la notion de personnage. Il s’agit de montrer comment un système de valeurs est véhiculé sans passer par l’identité d’un personnage mais en se fondant sur l’évocation d’une sensorialité commune au vivant, qu’il s’agisse d’humain ou de non humain comme c’est le cas en particulier dans l’ Histoire véritable grâce au procédé de la métempsycose. L’ Histoire véritable , au même titre que les Lettres persanes , illustre ainsi la manière dont l’écriture de Montesquieu interroge les mécanismes de projection dans l’altérité à travers des dispositifs fictionnels qui ne sont pas centrés autour de la notion de personnage.
Comparison of Refractive Prediction Accuracy With Three Optical Devices
Authors: Cheng Shi-Ming , Li Xi , Zhang Jia-Sheng , Mei Jian-qi , Shi Gui-lian , Lin Junhai , Li Tian-tian , Yu A-Yong 
Published: January 2023

Purpose:
To investigate refractive prediction accuracy with the OA-2000 (Tomey), Anterion (Heidelberg Engineering), and IOLMaster 500 (Carl Zeiss Meditec AG) in patients with cataract.

Methods:
Patients with cataract referred for phacoemulsification were enrolled and scanned with the OA-2000, Anterion, and IOLMaster 500 in random order. The success rate of axial length (AL) measurements per device was calculated and a chi-square test was used to identify the differences in acquisition rate between the three devices. The Bland-Altman method was used to appraise the agreement of biometric parameters between the three devices. Four different formulas (Barrett Universal II [BUII], Haigis, Holladay 1, and SRK/T) were included in the study. The parameters of refractive prediction accuracy comprised predictive error (PE), absolute PE (AE), and percentages of eyes with a PE within ±0.50, ±0.75, and ±1.00 diopters (D).

Results:

The acquisition rates of AL measurements with the OA-2000 and Anterion were 97.35% and 94.70%, respectively (chi-square = 3.82,
P
> .05). A significantly lower acquisition rate of 84.82% was obtained with the IOLMaster 500 compared with the other two devices (
P
< .05). Bland-Altman analysis identified good agreement between the three biometers with narrow 95% limits of agreement for flat and steep keratometry (K1 and K2), anterior chamber depth (ACD), and AL. For PE, only the differences between the Anterion and IOLMaster 500 with the Barrett UII and Haigis formulas were statistically significant (
P
< .05). The three devices revealed no statistically significant differences in MAE, MedAE, and the proportion of eyes with a PE within ±0.50, ±0.75, and ±1.00 D (
P
> .05).

Conclusions:
The OA-2000 and Anterion showed a similarly higher acquisition rate of AL measurements than the IOLMaster 500 in patients with cataract. Good agreement for K1, K2, ACD, and AL was found between the three biometers. Regarding refractive prediction accuracy, the Anterion did not significantly outperform both the OA-2000 and IOLMaster 500.

[
J Refract Surg
. 2023;39(1):48–55.]
Exploring Older Adult Health Literacy in the Day-to-Day Management of Polypharmacy and Making Decisions About Deprescribing: A Mixed Methods Study
Authors: Gillespie Robyn , Mullan Judy , Harrison Lindsey 
Published: January 2023

Background:
Polypharmacy use in older adults is increasing and sometimes leads to poor health outcomes. The influence of health literacy in managing polypharmacy and making decisions about stopping medication has received limited attention.

Objective:
A mixed methods design was used to measure and investigate the influence of health literacy in the management of polypharmacy and decisions about deprescribing. Phase 1 involved two cross-sectional surveys, one with older adults using five or more medications and the other with general practitioners (GPs).

Methods:
Older adult health literacy was measured using the All Aspects of Health Literacy Scale. Phase 2 employed individual interviews with both older adults and GPs and further explored the reported use of health literacy in practice. SPSS version 24 was used to conduct descriptive statistical analysis of the Phase 1 survey responses and Phase 2 interviews were analyzed using thematic analysis with the assistance of NVivo 12.

Key Results:
Phase 1 survey responses were received from 85 GPs and 137 older adults. Phase 2 interviews were conducted with 16 GPs and 25 older adults. Phase 1 results indicated that self-reported older adult health literacy was high, and that GPs believed older patients could engage in decisions about deprescribing. Phase 2 findings showed that older adults developed and employed complex health literacy practices to manage medications between consultations; however, few reported using their health literacy skills in consultations with their GPs. GPs noted that older adult involvement in decision-making varied and generally thought that older adults had low health literacy.

Conclusion:

Older adults reported using health literacy practices in the management of their sometimes-complex medication regimens. However, the role of health literacy in deprescribing decision-making was limited. The mixed methods approach allowed greater insight into older adult and GP practices that influence the acquisition and use of health literacy. [

HLRP: Health Literacy Research and Practice
. 2023;7(1):e14–e25.

]

Plain Language Summary:
This report explores health literacy in the use of multiple medications and decisions to stop using medication/s in older age. Older adults reported good heath literacy and practiced many health literacy skills in the management of their medications. However, they did not always report the use of their health literacy skills when discussing their medications with their family doctor.
Problematic screen media use in children and adolescents attending child and adolescent psychiatric services in a tertiary care center in North India
Authors: Raju Venkatesh , Sharma Akhilesh , Shah Ruchita , Tangella Ravikanth , Yumnam Sana Devi , Singh Jyoti , Yadav Jaivinder , Grover Sandeep 
Published: January 2023

ABSTRACT

Objective:
The present clinic-based study aimed to evaluate screen media use among children and adolescents who had a mental disorder.

Methods:
Two hundred twelve parents of children and adolescents attending the child and adolescent psychiatric services were approached. They were asked to rate the screen media use of their child brought for psychiatric consultation using the Problematic Media Use Measure-Short Form (PMUM-SF). The DSM-5 criteria of internet gaming disorder (IGD) were applied using the PMUM-SF, which contained nine items equivalent to nine items of IGD.

Results:
The mean age of the patients was 13.16 years (SD: 4.06; range: 0.8–18). Only 28.3% (n = 60) were aged less than 12 years. The most common primary diagnosis was neurodevelopment disorder (n = 82; 38.7%), followed by neurotic disorder (n = 62; 29.2%) and mood disorder (n = 30; 14.2%). The most common screen media used was television (n = 121; 57.1%) followed by the mobile phone (n = 81; 38.2%). The average screen time was 3.14 hours, with a range of 0.5–7 hours, and more than two-third of children and adolescents used screen gadgets for more than the recommended duration. Slightly more than one-fourth (22.2%) of children and adolescents with mental disorders fulfilled the DSM-5 criteria of IGD. When those with and without screen media addiction were compared, those with screen media addiction were more often male, from joint or extended families, more often diagnosed with neurodevelopmental disorders and disruptive disorder, and were less often diagnosed with neurotic disorders.

Conclusion:
About one-fourth of the children and adolescents with mental disorders had screen media addiction, and two-thirds of them used screen media for more than the recommended duration.
Prevalence of negative mental health status during COVID-19 pandemic among general population of seven Arab countries: A cross-sectional study of 28843 participants
Authors: Abdelsattar Nada K. , Alrawi Aya Ghiath , Abdelraoof Mohamed Ibrahim , Zaazouee Mohamed S. , Elsayed Sarah Makram , Farhat Abdullah M. , El-Shafea Mahmoud Abd , Abdeltawab Ahmed K. , Ali Menna S. , Madeeh Alyaa K. , Assar Ahmed , Mohammed Manar H. , Abdullah Eman A. , Ragab Khaled M. , Abd-ElGawad Mohamed , Elsherif Mohamed , Rahim Inas Abd El , Ebada Mahmoud A. 
Published: January 2023

ABSTRACT

Background:
Previous studies documented a narrow scope of knowledge about the negative mental health status during the lockdown following the COVID-19 pandemic, especially in Arab countries.

Aim:
We aimed to assess the association between negative mental health status and the COVID-19 pandemic and determine the different factors affecting mental health among the general population of seven Arab countries.

Methods:
This study is a multinational cross-sectional questionnaire-based survey conducted online from June 11, 2020 to June 25, 2020. The depression, anxiety, and stress Scale 21 Items (DASS-21) and the Event scale–Revised Arabic version (IES-R-13) scales were used. Multiple linear regressions were performed to study the association between the scales’ total scores with COVID-19 and demographic characteristics.

Results:
A total of 28,843 participants from seven Arab countries were included. During the COVID-19 pandemic, the prevalence of mental health disorders has significantly increased. A total of 19006 participants (66%) were affected by variable degrees of depression, 13,688 (47%) had anxiety, and 14,374 (50%) had stress ranging from mild to severe. Higher levels were associated with other factors, such as lower age, female gender, chronic disease, unemployed, fear of getting infected, and a history of psychiatric disorders.

Conclusion:
Our study findings show an increased incidence of mental disorders during the pandemic. This is expected to play a crucial role in guiding a psychological support strategy provided by healthcare systems to the general public during pandemics.
Publication of studies registered in Clinical Trials Registry of India: An audit of mood disorder research protocols from 2009-2019
Authors: Menon Vikas , Varadharajan Natarajan , Joseph Rini , Praharaj Samir Kumar , Andrade Chittaranjan 
Published: January 2023

ABSTRACT

Background:
Selective publication of studies has important scientific, ethical, and public health implications.

Aim:
We studied selective publication among mood disorder research protocols registered in the Clinical Trials Registry of India (CTRI) database. We also examined the frequency and nature of protocol deviations among the published articles.

Methods:
Using a systematic search strategy, we examined the publication status of all mood disorder-related research protocols registered in the CTRI database from inception till December 31, 2019. Logistic regression analysis was used to identify variables associated with selective publication.

Results:
Of 129 eligible protocols identified, only a third (n = 43, 33.3%) were published in literature; among those published, only 28 (21.7%) were placed in MEDLINE indexed journals. Protocol deviations were observed in more than half of the published papers (n = 25, 58.1%); many of these (41.9%) were related to sample size deviations, though, importantly, deviations in primary and secondary outcomes were also noted (16.2%). Retrospective registration of trials (odds ratio, 2.98, 95% confidence interval, 1.32–6.71) was significantly associated with publication; other variables, such as funding status or multicentric sampling, were not associated with eventual publication.

Conclusions:
Two out of three mood disorder research protocols registered in India do not translate into published research. These findings from a low- and middle-income country with limited spending on health care research and development represent wastage of resources and raise scientific and ethical concerns about unpublished data and futile patient participation in research.
Evidence-based integration of yoga in psychiatric practice
Authors: Gangadhar B. N. 
Published: January 2023

ABSTRACT
Yoga has been put to test in clinical medicine to build evidence. There has been a steep rise in yoga research through 2010, threefold in the next decade. Despite challenges, clinicians have explored yoga intervention in several disorders. The available data have been examined using meta-analysis when there are more studies. Psychiatric disorders treated with yoga have attracted more research. Some examples include depression, schizophrenia, anxiety, obsessive–compulsive disorder (OCD), somatoform pain, addiction, mild cognitive impairment, and elderly and childhood disorders. Current manuscript focuses on highlighting the major steps towards generating evidence that have led to integration of yoga into psychiatry practice. It also discusses various challenges and the way forward.
Predictive value of hepatic venous pressure gradient and efficacy and significance of early PTVE for gastrointestinal bleeding after TACE for liver cancer
Authors: Wei Jian , Hu Yuefeng , Yu Jianan , Yin Chao , Chen Guang , Jin Long 
Published: January 2023

Aims:
To investigate the predictive value of hepatic venous pressure gradient (HVPG) and the efficacy and significance of early percutaneous transhepatic varices embolization (PTVE) for gastrointestinal bleeding after transcatheter arterial chemoembolization (TACE) for liver cancer.

Methods and Materials:
This retrospective study enrolled 60 patients diagnosed with stage B or stage C liver cancer, according to the Barcelona Clinic Liver Cancer (BCLC) staging system, between December 2019 and October 2021. TACE and HVPG measurement (>16 mmHg or >20 mmHg) were performed on all 60 patients, who were randomized into control and experimental (PTVE) groups. All patients were followed up for 12 months.

Statistical Analysis Used:
SPSS 20.0 software was used for data analysis. The two groups were compared with respect to the initial occurrence time of hemorrhage after TACE, recurrence time of hemorrhage, liver function, TACE frequency, TACE type, and tumor control.

Results:
The initial hemorrhage rates at one, three, six, and 12 months after TACE were 3.2%, 12.9%, 22.6%, and 48.4%, respectively, in the control group (n = 31) and 0%, 0%, 3.4%, and 10.3%, respectively, in the PTVE group (n = 29). Differences between the groups in terms of initial hemorrhage rate at six and 12 months postoperatively were significant (P < 0.05). The recurrence rates of hemorrhage at one, three, six, and 12 months after TACE were 11.1%, 22.2%, 22.2%, and 33.3%, respectively, in 27 patients in the control group. In eight patients in the PTVE group, the corresponding rates were 0%, 0%, 0%, and 25.0%. The differences between the groups in the recurrence rate of hemorrhage at the four time points were significant (P < 0.05). At six months postoperatively, liver function recovery and remission were noted in eight (25.8%) and 18 (66.7%) patients, respectively, in the control group; these events were noted in 10 (34.5%) and 19 patients (65.5%), respectively, in the PTVE group, and the difference between the groups was not significant (P > 0.05). In the control group, TACE was performed for a total of 94 times on 31 patients within 12 months, including conventional transcatheter arterial chemoembolization (C-TACE, 75.5%) and the drug-eluting bead TACE (DEB-TACE, 24.5%); the objective response rate (ORR) was 39.3%. In the PTVE group, TACE was performed for a total of 151 times on 29 patients within 12 months, with an average of 5.21 times on each patient, including the C-TACE (57.6%) and DEB-TACE (42.4%); the ORR was 60.1%. Differences in TACE frequency, proportion of C-TACE/DEB-TACE, and ORR were significant between the two groups (P < 0.05).

Conclusion:
HVPG can accurately evaluate gastrointestinal bleeding after TACE in patients with liver cancer. Early PTVE can significantly lower the risk of gastrointestinal bleeding and help TACE control tumor progression in patients with an HVPG >16 mmHg or >20 mmHg.
Preoperative tumor abnormal protein is a promising biomarker for predicting hepatocellular carcinoma oncological outcome following curative resection
Authors: Cai Huayong , Li Wenxin , Zhang Yu , Hua Xiangdong 
Published: January 2023

Introduction and Objectives:
The objective of this study was to explore the potential relationship between tumor abnormal protein (TAP) and the prognosis of hepatocellular carcinoma (HCC) after a radical hepatectomy.

Patients or Materials and Methods:
This retrospective study included 168 HCC patients (tumor recurrence in 78 patients) who underwent a curative resection from January 2018 to June 2020. The whole population was categorized into a TAP high (≥224.6 μm2) or a TAP low group (<224.6 μm2).

Results:
There was no correlation between maximum tumor size and TAP. In the whole population or subgroups stratified by maximum tumor size, the recurrence-free survival (RFS) rate of the TAP low group was significantly higher than TAP high group (P < 0.05 for all). The multivariate analysis revealed that TAP (hazard ratio [HR], 3.47; 95% confidence interval [CI], 2.18–5.51; P < 0.001), large tumor size (HR, 2.18; 95% CI, 1.36–3.49; P < 0.001), poor tumor differentiation (HR, 0.53; 95% CI, 0.33–0.84; P = 0.007), and presence of microvascular invasion (MVI) (HR, 2.03; 95% CI, 1.28–3.22; P = 0.003) were independently associated with RFS. The prognostic implication of the nomogram incorporating TAP, maximum tumor diameter, tumor differentiation, and MVI was stronger than the model without TAP.

Conclusion:
The present study suggests that higher preoperative TAP is correlated with undesirable prognosis in HCC patients who underwent a radical hepatectomy. Our study provides a robust nomogram for RFS of postoperative HCC patients.
Conjunctival inflammation and dry eye symptoms at day 100 post-transplantation do not predict risk for chronic graft-versus-host disease
Authors: Shah Ankit M , Galor Anat , Mones Karla , Jean Pepita , Komanduri Krishna V , Wang Trent P 
Published: January 2023

PURPOSE:
Chronic graft-versus-host disease (cGVHD) is a significant cause of morbidity and mortality among patients after allogeneic hematopoietic stem cell transplant (HCT). The objective of our study was to determine if early assessment of matrix metalloproteinase-9 (MMP-9) and dry eye (DE) symptoms (via the DE Questionnaire-5 [DEQ-5]) had prognostic utility for the development of cGVHD and/or severe DE symptoms after HCT.

MATERIALS AND METHODS:
This was a retrospective study of 25 individuals who underwent HCT and had MMP-9 (InflammaDry) and DEQ-5 performed on day 100 post-HCT (D + 100). Patients also completed the DEQ-5 at 6, 9, and 12 months post-HCT. The development of cGVHD was determined by chart review.

RESULTS:
Overall, 28% of patients developed cGVHD over a median follow-up of 229 days. At D + 100, 32% of patients had a positive MMP-9 in at least one eye and 20% had a DEQ-5 ≥6. However, neither the presence of a positive MMP-9 nor a DEQ-5 score ≥6 at D + 100 predicted the development of cGVHD (MMP-9: hazard ratio [HR]: 1.53, 95% confidence interval [CI]: 0.34-6.85, P = 0.58; DEQ-5 ≥6: HR: 1.00, 95% CI: 0.12-8.32, P = 1.00). In addition, neither of these measures predicted the development of severe DE symptoms (DEQ-5 ≥12) over time (MMP-9: HR: 1.77, 95% CI: 0.24-12.89, P = 0.58; DEQ-5 >6: HR: 0.03, 95% CI: 0.00-889.93, P = 0.49).

CONCLUSION:
Within our small cohort, DEQ-5 and MMP-9 assessment at D + 100 did not predict the development of cGVHD or severe DE symptoms.
Diş Hekimliği Hizmetlerinde Hastaların Sağlık Kurumu Seçimini Etkileyen Faktörlerin Değerlendirilmesi
Authors: GÜMÜŞOK Mustafa , ERTUĞRUL Ayşe Nilgün 
Published: January 2023

Amaç: Bu çalışmanın amacı, ağız ve diş sağlığı hizmeti alan tüketicilerin, sağlık kuruluşu tercihi üzerinde etkili olan faktörleri belirlemek, başlıca etkili olan faktörlerin, tüketicilerin sosyo-demografik özelliklerine ait değişkenlere göre farklılaşıp farklılaşmadığını tesbit etmektir.
Örneklem ve Yöntem: Bu doğrultuda Ankara’da faaliyet gösteren kamuya bağlı bir ağız ve diş sağlığı hastanesine tedavi için başvuran 411 hastaya anket uygulanarak gerçekleştirilmiştir. Çalışmaya 18 yaş ve üstü bireyler dahil edilmiştir. Verilerin analizinde SPSS 20.0 paket programından yararlanılarak, sonuçlar %95’lik güven aralığında, P
An analysis of curriculum renewal in ESP context
Authors: Xaydarova Umida 
Published: January 2023

This article is devoted to the research of the foreign language curriculum set by the department of language training. Specifically, it proposes some changes to the current curriculum of the module “English for lawyers”. In fact, the data were collected from second-year learners and the curriculum of this module. The current curriculum for this module partially meets the standards of the university. The research entails several steps prior to the drawn conclusion. The first step was carried out through needs analysis in order to gather sufficient data about the learners and their preferences. Secondly, the existing curriculum was researched and its advantages and disadvantages were found out. Some drawbacks contain inappropriate teaching materials, lack of legal writing and not well-explained assessment criteria. The gathered outcomes helped to provide some suggestions which include changes regarding the syllabus, textbooks, and methods of the teachers. All these suggestions are based on the drawbacks and advantages of the curriculum. The suggested curriculum includes the integration of all skills; content, skill and task-based syllabus; reading novels related to their profession and succinct explanation of the tasks as well as the assessment criteria. All of these suggestions would be effective for the further development of future lawyers.