bluuebunny/crossref_metadata_2025_split huggingface dataset:
Register Forschungsförderung der Deutschen Gesellschaft
für Plastische, Rekonstruktive und Ästhetische Chirurgie
(DGPRÄC) und Forschungsförderungs-Bericht
2021/2022
Authors: Moellhoff N. , Prantl L. , Behr B. , Beier J.P. , Daigeler A. , Dragu A. , Eisenhardt S.U. , Fuchs P.C. , Germann G. , Hirsch T. , Horch R.E. , Infanger M. , Jakubietz R. , Kneser U. , Langer S. , Lehnhardt M. , Machens H.G. , Mailänder P. , Reichert B. , Radtke C. , Schaefer D.J. , Siemers F. , Vogt P.M. , Menke H. , Giunta R.E. 
Published: February 2023

Zusammenfassung
Hintergrund Forschung ist ein integraler Bestandteil der akademischen
Medizin. In der Plastischen Chirurgie stellt sie die Weichen für
Innovationen des Fachgebietes. In dieser Studie soll die Forschungsleistung der
Plastischen Chirurgen in Deutschland und assoziierten Kliniken im
deutschsprachigen Raum für den Zeitraum 2021/2022 dargestellt
und mit den Vorjahreszeiträumen verglichen werden.
Material und Methoden Der E-Mail-Verteiler des Konvents der leitenden
Plastischen Chirurgen der DGPRÄC wurde zur Kontaktaufnahme mit
Klinikdirektor*innen genutzt. Diese wurden um Mitteilung der gestellten,
in Begutachtung befindlichen, geförderten und abgelehnten Projekte
jeglicher öffentlicher, nicht-öffentlicher, industrieller oder
anderer Förderinstitute gebeten. Die Abfrage erfolgte über eine
eigens eingerichtete Online-Datenbank und wurde ebenfalls über das
Geförderte Projekte Informationssystem (GEPRIS) ermittelt.
Zusätzlich wurde die Forschungsinfrastruktur an den jeweiligen
Standorten abgefragt.
Ergebnisse Es wurden 105 Anträge bei 54 verschiedenen
Fördermittelgebern aus 20 plastisch-chirurgischen Standorten mitgeteilt.
37 Förderanträge wurden bei den großen
öffentlichen Förderinstituten DFG, BMBF, BMWi, BMG, BMVg, G-BA
und EU gestellt. Davon waren 59,5% (22/37) DFG, je 13,5%
(5/37) BMBF und EU, 5,4% (2/37) BMWi und je 2,7%
(1/37) BMG, BMVg, G-BA Anträge. Das durchschnittliche
Fördervolumen der bewilligten Anträge dieser
Fördermittelgeber betrug 401,515 Euro. Bewilligte DFG-Anträge
waren am häufigsten dem Fachkollegium 205–27 Orthopädie,
Unfallchirurgie, rekonstruktive Chirurgie zugeordnet (n=10/16,
62,5%). Im zeitlichen Verlauf der Erhebung des Forschungsregisters zeigt
sich ein Anstieg der im Register gemeldeten und als gefördert
angegebenen Anträge. 70,0% (14/20) der teilnehmenden
Standorte verfügten über ein eigenes experimentelles
Forschungslabor, während lediglich 40,0% (8/20)
über ein eigenes klinisches Studienzentrum verfügten.
Schlussfolgerung Der Forschungsförderungs-Bericht
2021/2022 unterstreicht erneut die beeindruckende Forschungsleistung der
Gemeinschaft der Plastischen Chirurg*innen.
Degree of pharyngeal deformation caused by pharyngeal endoscopic submucosal dissection is associated with the incidence of aspiration pneumonia
Authors: Abe Makoto , Kawahara Yoshiro , Obayashi Yuka , Baba Yuki , Hamada Kenta , Sakae Hiroyuki , Kono Yoshiyasu , Kanzaki Hiromitu , Iwamuro Masaya , Kawano Seiji , Makino Takuma , Noda Yohei , Marunaka Hidenori , Okada Hiroyuki 
Published: February 2023

Abstract
Background and study aims Endoscopic submucosal dissection (ESD) is one of the most minimally invasive treatments for superficial squamous cell cancer of the pharynx. However, aspiration pneumonia (AsP) associated with postoperative deformity of the pharynx may occur. The purpose of this study was to investigate the frequency of AsP and the degree of pharyngeal deformity after pharyngeal ESD.
Patients and methods This was a retrospective observational study of patients who underwent pharyngeal ESD at Okayama University Hospital between 2006 and 2017. The degree of pharyngeal deformation was assessed using the pharyngeal deformation grade (PDG). The primary endpoint was the frequency of AsP as a long-term adverse event.
Results Among the 52 patients enrolled, nine developed aspiration pneumonia, with a 3-year cumulative incidence of 9.0 % (95 % confidence interval [CI], 3.3 %–22.0 %). There were 16, 18, 16, and two patients that had PDG 0, 1, 2, and 3, respectively. Patients with a history of radiotherapy, as a treatment of head and neck cancer (44.4 % vs. 11.6 %; P = 0.02) and the high PDG group (PDG 2 and 3) (77.8 % vs. 25.6 %; P = 0.005) had a significantly higher incidence of AsP. The 3-year cumulative incidence rate of AsP after ESD in the high PDG group was significantly higher than that in the low PDG group (PDG 0 and 1) (23.9 % [95 %CI, 9.2.–49.5%] vs. 0 %; P = 0.03).
Conclusions The incidence of aspiration pneumonia in the long-term course after pharyngeal ESD was revealed. The incidence of aspiration pneumonia may be associated with pharyngeal deformity, but further studies are needed.
Endoscopic calcium electroporation for colorectal cancer: a phase I study
Authors: Broholm Malene , Vogelsang Rasmus , Bulut Mustafa , Stigaard Trine , Falk Hanne , Frandsen Stine , Pedersen Dorte Levin , Perner Trine , Fiehn Anne-Marie Kanstrup , Mølholm Ida , Bzorek Michael , Rosen Andreas Weinberger , Andersen Christina Søs Auður , Pallisgaard Niels , Gögenur Ismail , Gehl Julie 
Published: February 2023

Abstract
Background and study aims Colorectal cancer is one of the most common malignancies, with approximately 20 % of patients having metastatic disease. Local symptoms from the tumor remain a common issue and affect quality of life. Electroporation is a method to permeabilize cell membranes with high-voltage pulses, allowing increased passage of otherwise poorly permeating substances such as calcium. The aim of this study was to determine the safety of calcium electroporation for advanced colorectal cancer.
Patients and methods Six patients with inoperable rectal and sigmoid colon cancer were included, all presenting with local symptoms. Patients were offered endoscopic calcium electroporation and were followed up with endoscopy and computed tomography/magnetic resonance scans. Biopsies and blood samples were collected at baseline and at follow-up, 4, 8, and 12 weeks after treatment. Biopsies were examined for histological changes and immunohistochemically with CD3/CD8 and PD-L1. In addition, blood samples were examined for circulating cell-free DNA (cfDNA).
Results A total of 10 procedures were performed and no serious adverse events occurred. Prior to inclusion, patients reported local symptoms, such as bleeding (N = 3), pain (N = 2), and stenosis (N = 5). Five of six patients reported symptom relief. In one patient, also receiving systemic chemotherapy, clinical complete response of primary tumor was seen. Immunohistochemistry found no significant changes in CD3 /CD8 levels or cfDNA levels after treatment.
Conclusions This first study of calcium electroporation for colorectal tumors shows that calcium electroporation is a safe and feasible treatment modality for colorectal cancer. It can be performed as an outpatient treatment and may potentially be of great value for fragile patients with limited treatment options.
Survival Outcome in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Support: Early Experience from a University Hospital in Thailand
Authors: Duangpakdee Pongsanae , Sakkarat Sasitorn , Sangkhathat Surasak 
Published: February 2023

AbstractObjective Extracorporeal membrane oxygenation (ECMO) is a relatively new technology used for life support in patients with cardiopulmonary failure from various causes. The objective of this study is to review the first 5-year experience in adopting this technology in a teaching hospital in southern Thailand.Methods The data of ECMO-supported patients in Songklanagarind Hospital, from the years 2014 to 2018, were retrospectively reviewed. Data sources were from electronic medical records and the database of the perfusion service. Parameters in focus included prior conditions and indications of ECMO, type of ECMO and cannulation method, complications during and after the treatment, and discharge statuses.Results A total of 83 patients received ECMO life support during the 5-year period and the number of cases per year increased. The proportion of venovenous: venoarterial ECMO in our institute was 49:34 cases and there were three cases who used ECMO as a part of cardiopulmonary resuscitation. Moreover, there were 57 cases who used ECMO for cardiac failure and 26 cases were for respiratory causes, while premature withdrawal was decided in 26 cases (31.3%). Overall survival from ECMO was 35/83 cases (42.2%) and survival to discharge was 32/83 (38.6%). During therapy, ECMO could restore serum pH to the normal range in all cases. Furthermore, those who used ECMO for respiratory failure had significantly higher survival probability (57.7%) when compared to the cardiac counterpart (29.8%, p-value = 0.03). Patients with younger ages also had significantly better survival outcomes. The most common complications were cardiac (75 cases, 85.5%), followed by renal (45 cases, 54.2%), and hematologic systems (38 cases, 45.8%). In those who survived to discharge, average ECMO duration was 9.7 days.Conclusion Extracorporeal life support is a technology that bridges the patients with cardiopulmonary failure to their recovery or definitive surgery. Despite the high complication rate, survival can be expected, especially in respiratory failure cases and relatively young patients.
Complications of Transcatheter Arterial Chemoembolization for Treatment of Primary Liver Cancer
Authors: Novelli Paula M. , Gustafson Christopher , Orons Philip D. 
Published: February 2023

AbstractTranscatheter arterial chemoembolization (TACE) is the standard practice in treating both primary and metastatic liver neoplasms. TACE is a practical, minimally invasive procedure involving the delivery of chemotherapeutic agents into the artery supplying a tumor while simultaneously embolizing its blood supply. This approach can be used for curative and palliative intent across multiple cancer types. Historically, TACE has been instrumental in the treatment algorithms for hepatocellular carcinoma, allowing patients with unresectable disease to be downstaged and to slow disease progression, affording opportunities for transplantation and increased survival. Although benefits of TACE include lower morbidity and mortality versus systemic chemotherapy and surgical approaches, the procedure has risks and complications. Interventional radiologists and physicians involved in the care of these patients should be aware of the associated complications including avoidance and treatment strategies.
Spontaneous Resolution of a Humeral Intracondylar Fissure in a Skeletally Immature French Bulldog
Authors: Garland Ben William , Dumitru Emilian Adrian , Ororbia Alejandro , Oxley Bill 
Published: February 2023

AbstractA 4-month-old male entire French bulldog was presented for the investigation of acute left thoracic limb lameness. Computed tomography (CT) revealed a right-sided humeral intracondylar fissure (HIF) and a left-sided medial humeral condylar fracture which was managed by open reduction and internal fixation. Follow-up CT at 36 days after surgery revealed healing of the condylar fracture and partial resolution of the HIF, which was radiographically unapparent on further CT images 105 days thereafter (at 220 days of life). To the best of the authors' knowledge, this is the first reported case of spontaneous resolution of a HIF beyond the normal age of reported humeral condyle ossification center closure.
Comparing content marketing strategies of digital brands using machine learning
Authors: Chen Yulin 
Published: February 2023

AbstractThis study identifies and recommends key cues in brand community and public behavioral data. It proposes a research framework to strengthen social monitoring and data analysis, as well as to review digital commercial brands and competition through continuous data capture and analysis. The proposed model integrates multiple technologies, analyzes unstructured data through ensemble learning, and combines social media and text exploration technologies to examine key cues in public behaviors and brand communities. The results reveal three main characteristics of the six major digital brands: notification and diversion module; interaction and diversion module; and notification, interaction, and diversion module. This study analyzes data to explore consumer focus on social media. Prompt insights on public behavior equip companies to respond quickly and improve their competitive advantage. In addition, the use of community content exploration technology combined with artificial intelligence data analysis helps grasp consumers’ information demands and discover unstructured elements hidden in the information using available Facebook resources.
Development of magnetorheological fluids within 3D printed elastomeric cellular structures with an accumulator
Authors: Park Jungjin , Choi Young T. , Flatau Alison B. , Wereley Norman M. 
Published: February 2023

In this study, a magnetorheological fluid (MRF) was encapsulated in a 3D printed cellular elastomeric encapsulant. Mechanical properties, such as stiffness and damping, of the encapsulant containing MRFs can be controlled via applied magnetic field. Such tunability can be exploited for adaptive vibration control or energy absorption systems. Here, MRF prepared with silicon oil (40% volume fraction) was injected into the 3D printed thermoplastic polyurethane (TPU) cellular encapsulant. The wall adjacent to the sealing layer had a circular opening and a TPU membrane was bonded to its perimeter so that the pressurized MRF could flow through the opening and be accumulated in the resulting pocket. An external magnetic field (0–350 mT) was applied to the sample at the time of uniaxial dynamic testing with 5% pre-strain. The MRF-TPU composites were characterized via cyclic force-displacement tests (1 Hz) under displacement amplitudes. The area of the force-displacement curve of the system with an accumulator is about 26% greater than one without an accumulator. The effect of the accumulator on the mechanical properties of the MRF-TPU composites was studied with strain amplitude and magnetic fields.
Key comparison BIPM.RI(I)-K4 of the absorbed dose to water standards of the NMIJ, Japan, and the BIPM in 60Co gamma radiation
Authors: Kessler C , Burns D , Morishita Y , Shimizu M , Kurosawa T 
Published: February 2023

Main text
A new key comparison of the standards for absorbed dose to water of the National Metrology Institute of Japan (NMIJ), Japan, and the Bureau International des Poids et Mesures (BIPM) was carried out in the 60Co radiation beam of the BIPM in February 2022. The comparison result, based on the calibration coefficients for two transfer standards and evaluated as a ratio of the NMIJ and the BIPM standards for absorbed dose to water, is 0.9952 with a combined standard uncertainty of 4.0 parts in 103. The result agrees within the uncertainties with the comparison carried out in 2009. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Multicritical phase transitions in multiply rotating black holes
Authors: Wu Jerry , Mann Robert B 
Published: February 2023

AbstractWe show that multi-critical points in which more than three phases coalesce are present in multiply rotating Kerr-anti de Sitter black holes ind-dimensions. We explicitly present a quadruple point for a triply rotating black hole ind = 8 and a quintuple point for a quadruply rotating black hole ind = 10. The maximal number of distinct phasesnis one larger than the maximal number of independent rotations, and we outline a method for obtaining the associatedn-tuple point. Situations also exist where more than three phases merge at sub-maximal multi-critical points. Our results show that multi-critical points in black hole thermodynamics are more common than previously thought, with systems potentially supporting many phases as long as a sufficient number of thermodynamic variables are present.
An optically transparent flexible metasurface absorber with broadband radar absorption and low infrared emissivity
Authors: Jing Huihui , Wei Yiqing , Kang Jinfeng , Song Chengwei , Deng Hao , Duan Junping , Qu Zeng , Wang Jiayun , Zhang Binzhen 
Published: February 2023

Abstract
The rapid development of surveillance technology has driven the research of multispectral stealth. Demand for infrared and microwave radar compatible stealth is becoming increasingly urgent in military applications. Herein, a versatile metamaterial absorber is designed and fabricated to simultaneously achieve ultra-broadband radar scattering reduction, low infrared emission, and high optical transparency. The designed structure consists of an infrared stealth layer, radar absorption layers, and backing ground. The infrared stealth layer employs specifically indium tin oxide (ITO) square patches, while the radar absorption layers can be obtained by stacking different size ITO patterned films of the same structure with high surface resistances, realizing broadband microwave stealth performance in the 1.98–18.6 GHz frequency range with an incident angle of 45°. The broad radar stealth and low infrared emissivity of 0.283 are consistent with the simulations and calculations. Furthermore, the designed structure exhibits characteristics such as polarization insensitivity, wide incident angles, optical transparency, and flexibility, allowing for a wide range of applications in various environments.
Low-energy physics in neutrino LArTPCs
Authors: Andringa S , Asaadi J , Bezerra J T C , Capozzi F , Caratelli D , Cavanna F , Church E , Efremenko Y , Foreman W , Friedland A , Gardiner S , Gil-Botella I , Himmel A , Junk T , Karagiorgi G , Kirby M , Klein J , Lehmann-Miotto G , Lepetic I T , Li S , Littlejohn B R , Mooney M , Reichenbacher J , Sala P , Schellman H , Scholberg K , Sorel M , Sousa A , Wang J , Wang M H L S , Wu W , Yu J , Yang T , Zennamo J 
Published: February 2023

Abstract
In this paper, we review scientific opportunities and challenges related to detection and reconstruction of low-energy (less than 100 MeV) signatures in liquid argon time-projection chamber (LArTPC) neutrino detectors. LArTPC neutrino detectors designed for performing precise long-baseline oscillation measurements with GeV-scale accelerator neutrino beams also have unique sensitivity to a range of physics and astrophysics signatures via detection of event features at and below the few tens of MeV range. In addition, low-energy signatures are an integral part of GeV-scale accelerator neutrino interaction final-states, and their reconstruction can enhance the oscillation physics sensitivities of LArTPC experiments. New physics signals from accelerator and natural sources also generate diverse signatures in the low-energy range, and reconstruction of these signatures can increase the breadth of Beyond the Standard Model scenarios accessible in LArTPC-based searches. A variety of experimental and theory-related challenges remain to realizing this full range of potential benefits. Neutrino interaction cross-sections and other nuclear physics processes in argon relevant to sub-hundred-MeV LArTPC signatures are poorly understood, and improved theory and experimental measurements are needed; pion decay-at-rest sources and charged particle and neutron test beams are ideal facilities for improving this understanding. There are specific calibration needs in the low-energy range, as well as specific needs for control and understanding of radiological and cosmogenic backgrounds. Low-energy signatures, whether steady-state or part of a supernova burst or larger GeV-scale event topology, have specific triggering, DAQ and reconstruction requirements that must be addressed outside the scope of conventional GeV-scale data collection and analysis pathways. Novel concepts for future LArTPC technology that enhance low-energy capabilities should also be explored to help address these challenges.
Temperature dependence of adhesion properties at liquid-aluminum/solid interfaces
Authors: Wu Jie , Rui Zhiyuan , Wang Zhongyu , Dong Yun 
Published: February 2023

Abstract
The adhesion problem of the liquid aluminum (Al) and solid surfaces in the production process has not been completely solved. In this paper, by performing the molecular dynamic simulations, we first establish models composed of liquid-Al/Al and liquid-Al/silicon (Si) systems, in which the region of solid temperature is from 100 K to 800 K. Then, the dependence between the adhesion force and the solid temperature is qualitatively investigated. The adhesion mechanism of liquid atoms is explored in terms of their diffusion behavior. The results show that there is an opposite effect of the temperature on adhesion properties between the liquid-Al/Al interface and the liquid-Al/Si interface. The thermal excitation effect induces enlargement of the probability of atomic collisions, which accounts for the increase of the adhesion force at the liquid-Al/Al interface. Conversely, the thermal excitation effect leads to the detachment of the atoms in contact with each other, which reduces the adhesion force at the liquid-Al/Si interface. Our findings reveal that the solid Al surface is aluminophilic but the solid Si surface is aluminophobic. In addition, the adhesion between liquid-Al and solid surfaces can be explained by the variation of the interfacial potential.
Effect of Two-Stage Solution on Microstructure and Mechanical Property of IN718 alloy fabricated by selective laser melting
Authors: Tian Wei , Cao Yu , Wang Li 
Published: February 2023

Abstract
The substructure characteristics and mechanical properties of IN718 alloy prepared by selective laser melting (SLM) in the as-deposited state and different solid solution states were studied. The effects of the substructure characteristics, which include the precipitates and grain boundary features, on the microhardness of the IN718 alloy were discussed. It was found that the main substructure of the as-deposited alloy is the cellular structure that is formed owing to the segregation band of Nb and Ti elements with a thickness of 50 nm. The two-stage solution process and single-stage solution process can both correct the microsegregation of the as-deposited state, but the two-stage solution process can make the composition more uniform; at the same time, it leads to a large number of twin boundaries. The δ phase precipitates largely in the single-stage solution process at 980 ℃, but the two-stage solution process can effectively inhibit the precipitation of the δ phase.The hardness of the alloy after two-stage solution is lower than that of the single-stage solution alloy. The main strengthening mechanism of the as-deposited alloy is strain strengthening,The strengthening effect of δ precipitate is lower than the strain strengthening produced by the grain boundary of the alloy.