bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gymnastics Puerperal Uterine Involution in the BPS Ririn Dwi SST Jelakombo Jombang
Authors: Yuniar Kristianingrum Dhita 
Published: January 2023

Kesembuhan ketika nifas adalah proses yang sangat penting untuk ibu ketika usai melahirkan, dikarenakan otot dan ligamen - ligamen pada pelvis meregang ketika hamil dan proses persalinan, seusai bersalin sedikit demi sedikit mengalami pemulihan ke bentuk dan ukuran normal. Tujuan dari peneliti ini adalah untuk mengetahui pengaruh senam nifas terhadap proses involusi uteri di BPM Ririn Dwi SST di Jelakombo, Kabupaten Jombang. Desain penelitian ini adalah analitik dengan metode studi cross-sectional dimana populasinya adalah ibu bersalin sebanyak 30 responden, dengan jumlah sampel sebanyak 25 responden yang diambil dengan menggunakan tehnik pengambilan sampel yaitu dengan cara aksidental sampling, penelitian dilaksanakan pada tanggal 15 Februari sampai dengan 15 Maret 2019 di BPS Ririn Dwi SST. Pengumpulan data menggunakan kuesioner dengan metode pertanyaan tertutup. Uji statistik yang digunakan adalah chi square. Hasil penelitian ini menunjukkan bahwa dari 25 responden yang mengalami involusi uteri baik terdapat 16 responden (66,6%) melakukan senam nifas dan 3 responden (12,5%) tidak melakukan senam nifas. Dari hasil uji chi square didapatkan X2 hitung > X2 tabel, sehingga diperoleh 7,900 > 3,841 artinya H0 di tolak dan H1 diterima artinya ada hubungan senam nifas dengan proses involusi uteri. Hal ini disebabkan karena dipengaruhi oleh beberapa faktor antara lain usia, paritas, mobilisasi dini, senam nifas. Senam nifas sangat mempengaruhi kecepatan pemulihan pada ibu pasca bersalin. Oleh karena itu perlu meningkatkan pelayanan dalam pemberian penyuluhan dan informasi tentang bagaimana melakukan senam nifas yang benar sehingga tujuan dalam mempercepat involusi uteri tercapai.
Relationship between Maternal Anemia and the Incidence of Anemia in Infants Aged 6-36 Months
Authors: Risca Fauzia Faurina , Wahyuntari Evi , Wahtini Sri 
Published: January 2023

Prevalensi anemia pada bayi dinegara berkembang yaitu 44-66%. Salah satu penyebab anemia pada bayi yaitu terjadi anemia pada ibu saat kehamilan. Tujuan penelitian untuk melihat hubungan anemia ibu dengan kejadian anemia pada bayi usia 6-36 bulan. Penelitian kuantatif dengan pendekatan cross sectional, populasi sebanyak 245 bayi Sampel yang digunakan bayi usia 6-36 bulan yang berkunjung di Wilayah kerja Puskesmas Kalasan. Penelitian dilakukan bulan Februari - Oktober 2020. Kriteria inklusi: bayi umur 6-36 bulan, tidak memiliki riwayat penyakit infeksi,dan mempunyai buku KIA. Kriteria eksklusi: bayi yang sedang sakit saat kunjungan imunisasi. Pengumpulan data menggunakan Kueisoner data dasar a) data sosio demografi (pekerjaan, umur, status pernikahan, dan pendidikan). Responden yang sesuai kriteria, kemudian diberi informed consent. Responden yang bersedia menjadi resposnden diminta mengisi lembar kuesioner data dasar yang telah dikembangkan oleh peneliti. Kemudian diperiksa kadar hemoglobin pada bayi dengan mengambil darah perifer. Analisa data menggunakan chi square. Variabel umur, pendidikan, pekerjaan tidak ada hubungan dengan anemia terlihat dengan nilai p > 0.05. Sedangkan variabel anemia ibu berhubungan dengan anemia pada bayi dengan nilai p < 0.05dengan OR 13.7 dengan IK 95% 5,3-35,2 yang artinya ibu hamil dengan anemia mempunyai kemungkinan 13,7 kali mengalami anemia pada bayi umur 6-36 bulan. Anemia ibu berhubungan dengan anemia pada bayi dengan OR 13.7 dengan yang artinya ibu hamil dengan anemia mempunyai kemungkinan 13,7 kali mengalami anemia pada bayi umur 6-36 bulan. Pemeriksaan Hb di anjurkan untuk semua bayi setelah usia 6 bulan untuk deteksi dini dan pengobatan anemia terutama pada bayi dengan riwayat anemia pada ibu.
Health Education : Audio Visual Media for Improving Mother’s Knowledge, Attitude, and Psychomotor of Breastfeeding Techniques
Authors: Mukhoirotin  , Masruroh Siti 
Published: January 2023

Lack of mother's knowledge about the correct management of lactation is the cause of mothers cannot breastfeed their babies with the correct technique which results in the baby not being able to suck effectively. If this condition is not treated, it will affect the growth of the baby, the growth and development of the baby is hampered. Efforts that can be made to deal with these problems are by providing health education with audiovisual media. The aim is to determine the effect of health education on mother's knowledge, attitudes and psychomotor about breastfeeding techniques. This study uses a Quasy-Exsperiment design, Pretest-Postest Control Group Design. The population in this study were all postpartum mothers at Paviliun Melati RSUD Jombang. The research subjects were 30 treatment respondents and 30 control respondents, using purposive sampling technique. Data were analyzed using Wilcoxon and Mann-Whitney with a significance level of 0.05. The results of the analysis test showed that there was an effect of health education on mother's knowledge, attitudes and psychomotor about breastfeeding techniques with a significance value of p<0.05, and there were differences in the effect of health education on mother's knowledge, attitudes and psychomotor about correct breastfeeding techniques in the group. treatment and control groups with a significance value of p<0.05. Health education uses effective audiovisual media to increase mother's knowledge, attitudes and psychomotor about breastfeeding techniques and can be used as alternative media in an effort to provide health information.
FirstIn SituTerrestrial Osbornite (TiN) in the Pyrometamorphic Hatrurim Complex, Israel
Authors: Galuskin Evgeny , Galuskina Irina O. , Kamenetsky Vadim , Vapnik Yevgeny , Kusz Joachim , Zieliński Grzegorz 
Published: January 2023

AbstractOsbornite (TiN) is extremely rare in nature (commonly found in enstatite meteorites) and has not yet been identified correctly to form naturally in terrestrial settings. Due to its thermodynamic stability and thermal shock resistance, TiN has wide industrial applications, mainly as coatings. However, as the melting temperature of TiN is very high (~3000°С), coatings are produced at much lower temperatures via physical or chemical vapor deposition. Also, anthropogenic analogues of osbornite are often observed in pyrometallurgical slags. Therefore, it is critical to distinguish between anthropogenic and naturally occurring osbornite. A detailed petrographic study was undertaken on in situ osbornite found within unusual gehlenite-bearing breccias from wadi Zohar, Negev Desert of the pyrometamorphic Hatrurim Complex. The Hatrurim Complex, which extends through Israel, Palestine, and Jordan within the Dead Sea Rift zone, mainly comprises larnite, gehlenite, and spurrite rocks. Osbornite, in close association with iron phosphides, barringerite, and schreibersite, occurs at contacts between gehlenite, paralava, and calcinated clasts of host sedimentary rocks. Based on investigation of pseudowollastonite and Fe-P series phases, osbornite is formed at low pressure, extremely high temperatures (~1200-1500°С), and reduced conditions, following pyrolysis of organic matter contained in the sedimentary protolith. This is the first identification of in situ osbornite in terrestrial rocks and indicates that high-temperature and highly reduced conditions, which are common for meteorites, may occur at/near the Earth’s surface as a result of sustained pyrometamorphism in particular settings. Our findings also provide relevant data and criteria for comparing osbornite occurrences elsewhere and ultimately evaluating their origins.
Validating field regeneration capacity for selected accessions of Gossypium hirsutum using callus induction and regeneration capacity
Authors: Tajo Sani Muhammad , Pan Zhaoe , He Shoupu , Jia Yinhua , Mahmood Tahir , Nazir Mian Fasil , Hu Daowu , Wang Liru , Sadau Salisu Bello , Ibrahim Sani , Auta Umar , Geng Xiaoli , Du Xiongming 
Published: January 2023

Abstract
Background: Gossypium hirsutumundergoes rapid clonal propagation to regenerate a mature plant through tissue culture. In this research, cotton leaf regeneration level for 21 accessions in the field (new leaves) was observed after the first harvest, and a comparison between field regeneration level and callus induction with its regeneration capacity (new shoots and roots) for the same 21 accessions was carried out. During the flowering stage of Gossypium hirsutum, biochemical (proline), and physiological (chlorophyll and carotenoid content) analysis was carried out. Phenotypic observations (plant height, leaf area, fresh leaf weight, dry leaf weight, number of flowers, and bolls) were also carried out on 21 accessions for each.
Result:A significant correlation between physiological parameters and callus induction was discovered. Callus induction and regeneration capacity of roots and shoots for hypocotyl, cotyledons and shoot tip tissues were used to validate field leaf regeneration level in the field after the first harvest. CCRI 24 showed significant leaf regeneration in the field and callus induction capacity through callus induction and regeneration.
Conclusion:We found a substantial relationship between field regeneration capability and callus induction with its regeneration capacity for the hypocotyl, cotyledons, and shoot tip. The results of this study showed that ZS061, Lumian 378, Jimian 863, and ZS065 have the highest moisture retention capacity while CCRI 24, Liaoyangduomaomian, and Beizhegongshemian have the lowest moisture retention. CCRI 24 have the highest leaves regeneration in the field while Beizhegongshemian has lowest leaves regeneration in the field. All our result provides a clue for check the regeneration capacity through leaf regeneration level in the field.
Identification of Impacts in the Town of San Pablo de Amalí, Ecuador, by Hidrotambo S.A.’s San José del Tambo Hydroelectric Power Plant by Means of a Multitemporal Analysis of Landscape Units for the Detection of Land Use Change Over 20 Years
Authors: Marín Jorge A. Espinosa , Perez Danilo , Rivera Diego , Fuentes Rodrigo , Conrad Rchael 
Published: January 2023

Abstract
This study identifies the effects of land use change in the area of direct influence of the Dulcepamba River for hydroelectric production in relation to vegetation, river course, and damage to the population, among others, through multi-temporal analysis of satellite images 20- years old, this study presents conclusive results based on a methodology for detecting land use change through multitemporal analysis, which was contrasted and verified with topographic and visual field identification, in the evaluation of the 4 time periods analyzed, exists change in the river and closed areas affected with changes influence of the riverbed, which affects the area where the local population lives and carries out their economic activities. The cause-effect relationship of the anthropic interventions in the river and the impacts on the area of the "village" and the "populated area" is also evidenced by comparing the representative images of each period in which there were significant changes, from October 2001 to December 2019
Perovskite quantum dots modulating upconversion nanomaterials for cancer early detections
Authors: He Yue , Rao Hongtao , Wang JingJing , Wu Ying , Han Caiqin , Yan Changchun , Temple Hunter , Zhang Le , Chen Wei , Liu Ying 
Published: January 2023

Abstract
The accurate diagnosis and treatment of cancer cell lesions need a high standard of detection technology. Fluorescent probes to perform cancer biomarker detection have become a popular research issue. However, fluorescent probes still face enormous challenges of complex design and difficult detection. In this work, we propose a novel composite material UCNP@SiO2+QDs based on the combination of rare earth upconversion (UCNP) and perovskite quantum dots (QDs) and design a new fluorescent probe MB-UCNP@SiO2+QDs with molecular beacon (MB) as the carrier, that can be excited by near-infrared light, emitted in the visible wavelength, specifically identified and highly sensitive. Under the excitation of 980 nm near-infrared light, the UCNP and QDs in the composite produced the maximum efficiency of energy transfer through fluorescence resonance, and the multi-emission light of UCNP synergistically excited the re-emission of QDs, and the energy transfer efficiency is 70.6%. By changing the doping ratio of QDs halogen elements in UCNP@SiO2+QDs, it is possible to modulate the precise luminescence of UCNP@SiO2+QDs in the entire wavelength range of visible light at different positions. The novel fluorescent probe is obtained using UCNP@SiO2+QDs and Black Hole Quencher-1 (BHQ1) quenching groups linked to the two respective sides of MB, selecting as the target of detection the myeloma cancer biomarker miRNA-155, a difficult diagnostic and complex developmental type, and have achieved specific recognition and low concentration of miRNA-155 and a detection limit of 73.5 pM. This fluorescent probe design can provide new ideas for the early diagnosis and treatment of cancer, tumors, and cardiovascular diseases.
CORALIS, an R package for ncRNA-target enrichment analysis based on experimentally validated interactions
Authors: Valle-Millares Daniel , Briz Verónica , Fernández-Rodríguez Amanda 
Published: January 2023

Abstract
Non-coding RNAs are key regulatory molecules that govern a myriad of biological process by interacting and modulating the expression of their target protein-coding genes. The combination of RNA large-scale sequencing and computational analyses has revealed the existence of a vast diversity of RNA species with essential roles in biological functions. However, dealing with the huge network of interactions has become a challenge and the urgent need for new computational tools has arisen. We present CORALIS, an R package for the statistical analysis and visualization of experimentally validated interactions between non-coding RNAs and their target genes (ncRNA-mRNA). So far, CORALIS supports miRNA, lncRNA, snRNA and snoRNA target enrichment analysis for several species such as Homo sapiens, and other human-model species such as Rattus norvegicus, Caenorhabditis elegans and Drosophila melanogaster, among others. Statistical tests (hypergeometric distribution test) are performed to estimate enriched target genes for non-coding RNAs defined by the user, and visualization tools allows to easily analyze the results. In conclusion, CORALIS allows identifying enriched target genes given a list of non-coding RNAs. CORALIS is freely accessible at https://github.com/Daniel-VM/CORALIS.
How do multi-stakeholder partnerships influence access to quality bean seed and variety turnover? Lessons from Burundi and Zimbabwe
Authors: Aseete Paul , Katungi Enid 
Published: January 2023

Abstract
Background
Crop breeding is an important pathway for increasing the yield potential and one of the strategies used to adapt smallholder agriculture to climate change in developing countries. Genetic gains, however, go to waste if farmers do not access modern varieties at the right time (before seed deteriorates) and pace. Ensuring fast, prompt, and sustained access to quality bean seed, just like seed of other leguminous crops, has however been a challenge in Sub Saharan Africa. The autogamous nature of the bean crop makes sustaining seed supply and demand hard. This therefore calls for innovative approaches among bean seed value chain actors to deliver quality seed of targeted varieties. One such approach is the use of Multi-Stakeholder Partnerships (MSPs).
Methods
In this study, we assess the impacts of MSPs on seed access, quality of seed, and variety turnover measured as the Area Weighted Age of the Variety (AWAVA). These MSPs were created in Burundi and Zimbabwe to improve the performance of the bean seed system by facilitating access to quality seed. To show the average treatment effect on the treated, the study used the endogenous treatments effects estimator under the control function framework and the change in change and difference in difference framework for Zimbabwe because we had pre and post treatment data.
Results
Our findings show that the MSP was associated with significant improvement in ranges of 27 -42% more access to seed of improved bean varieties among intervention communities. Also residing in an intervention area was associated with a 65% reduction in distance to bean seed markets. Results further revealed that the MSP approach could be associated with a reduction of the AWAVA of improved varieties grown by 4.4 years among high-intensive intervention groups in Burundi and by 5.2 years for Zimbabwe. Farmers in Burundi were also generally satisfied with production, market and consumption traits of varieties supplied.
Conclusions
Our results show that using a multi partner-based seed system approach coupled with supply of quality seed of superior varieties, capacity building, and promotion efforts lead to better seed access outcomes at farm level. These findings imply that MSPs can be an effective tool for delivering new varieties of legume crops to farmers, and thus reduce varietal turnover.
The structural basis of the divalent cation blocking on tetrameric cation channel
Authors: Irie Katsumasa , Oda Yoshinori , Sumikama Takashi , Oshima Atsunori , Fujiyoshi Yoshinori 
Published: January 2023

Abstract
Divalent cation blocking is observed in various tetrameric ion channels. For the blocking, a divalent cation is thought to stack in the ion pathway of the channel, but this has not yet been directly observed, so the blocking mechanism by these small divalent cations remains uncertain. Here, we elucidated the divalent cation blocking mechanism by reproducing the blocking effect into NavAb, a well-studied tetrameric sodium channel. Our crystal structures of NavAb mutants showed that the mutations increasing the hydrophilicity of the inner vestibule of the pore domain enable a divalent cation to stack on the ion pathway. Furthermore, molecular dynamics simulation showed that the stacking calcium ion repels the sodium ions at the bottom of the selectivity filter. These results suggest the primary mechanism of the divalent cation block in biologically essential channels.
Delayed Neuregulin-1 Treatment Initiates a Late Neuroprotective Early Regenerative and Autophagic Spatial Profiles in Mice following Ischemic Stroke
Authors: Noll Jessica , Augello Catherine , Kurum Esra , Pan Liuliu , Pavenko Anna , Nam Andy , Ford Byron 
Published: January 2023

AbstractNeuregulin-1 (NRG-1) has been shown to be neuroprotective and anti-inflammatory in rodent models following focal brain ischemia. However, the spatial transcriptional mechanisms involved in the effects of NRG-1 have not been investigated. In this study, we examined the spatial cellular and neuroinflammatory mechanisms employed by NRG-1 following stroke utilizing Nanostring Digital Spatial Profiling (DSP) technology. C57bl/6 mice were subjected to photothrombotic middle cerebral artery occlusion (MCAO). Animals were treated with NRG-1 (5ug/kg/day NRG-1 β) or vehicle beginning 24 hours after surgery, and then sacrificed at 3 days post-ischemia (dpi). Using GeoMX DSP technology, we examined the relative expression of 73 proteins in selected regions of interest (ROI) within the ischemic core, peri-infarct tissues, and peri-infarct normal tissue (PiNT) in controls and NRG-1 treated mice. FJB staining showed that delayed NRG-1 treatment did not significantly alter overall neuronal death, but it had profound effects on the neuroregenerative outgrowth environment. The ipsilateral core ROI demonstrated the most altered proteomic profile with 37 differentially regulated proteins related to autophagy and mitophagy, immune cell phagocytosis, and synaptic activity. NRG-1 upregulated synaptophysin by 2.10-fold while marginally rescuing neuronal proteins NeuN and MAP2. NRG-1 treatment induced the upregulation of ULK1, LC3B, ATG5, PINK1, and Park7 within the core region, suggesting successful autophagic flux restoration. NRG-1 treatment also increased Mertk, CD9, CSF1R/CD115, MHCII and Myelin Basic Protein (MBP). Phospho-Tau (S199) was increased 57-fold following stroke and further increased to 90-fold after NRG-1 treatment. The peri-infarct region showed increased astrocyte proteins along with BAG3, CD204/MSR1, phospho-Tau (S199) and Ki67, a marker of cell proliferation. Together, our findings showed that mechanisms of neuroprotection by NRG-1 following stroke occur in distinct spatial domains of the injured brain following ischemia. The data suggest that NRG-1 provides protection against further neuronal apoptosis and priming of an anti-inflammatory, neuroregenerative niche in a spatial manner, which could lead to novel treatment strategies for stroke.
Effect of individualized narrative nursing mode on mental health, cognitive function and limb function recovery of elderly patients with fracture complicated with cerebrovascular accident
Authors: Wang Yurong , Zhang Fang , Li Cuihua 
Published: January 2023

Abstract
Background: Fractures often occur in elderly patients. Osteoporosis caused by massive loss of calcium ions in the bones of elderly patients can easily lead to femoral fractures after suffering a low-and medium-energy injury. With the gradual entry of the aging society in China, the incidence of senile fracture is also gradually increasing. However, there is no report on the application of personalized narrative nursing to the mental health, cognitive function and limb function recovery of elderly patients with fracture complicated with cerebrovascular accident, in order to enhance the cognitive level of elderly patients with fracture complicated with cerebrovascular accident. This study was specially conducted with a positive attitude towards the disease and improving the life quality.
Methods: During July 2018 to July 2021, eighty elderly patients with fracture complicated with cerebrovascular accident cured were selected in our hospital. The patients were arbitrarily classified assigned control group (n=40) and study group (n=40). The former received routine nursing and the latter received personalized narrative nursing mode. The nursing satisfaction, functional independence scale (FIM), self-rating anxiety scale (SAS), self-rating depression scale (SDS), cognitive function, fracture healing time, length of hospital stays and hospitalization expenses were compared.
Results: The study group had a satisfaction rate of 100.00%, while the control group had 87.50%. The nursing satisfaction of the study group was higher (P<0.05). After 3 months of nursing, the FIM scores augmented. The FIM scores of upper and lower limbs in the study group were remarkably higher (P<0.05). A decrease in SAS and SDS scores was observed. The SAS and SDS scores of the study group were lower (P<0.05). Three months after discharge, the cognitive function score augmented. At 3 months after discharge, the study group had a higher cognitive function score (P<0.05). The fracture healing time, length of stay and cost of hospitalization in the study group were lower (P<0.05).
Conclusion: Personalized narrative nursing model can successfully enhance the mental health and cognitive function of elderly patients with fracture complicated with cerebrovascular accident, enhance the recovery of limb function, promote patients' nursing satisfaction, and alleviate the economic burden.