bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graves’ disease-induced immune thrombocytopenic purpura in an African female: a case report
Authors: Agyapong Kwabena Oteng , Folson Aba A. , Fiador Kate , Kootin-Sanwu Cecilia , Tufuor Martha , Bampoh Sally Afua , Fiscian Henrietta , Wonkyi Roland 
Published: April 2023

Abstract
Background
Immune thrombocytopenic purpura is a condition associated with an unusual, unexplained, and sometimes very severe reduction in the level of platelets in the blood. Though documented, its association with Graves’ disease is not very common and can easily be missed or misdiagnosed, leading to excessive bleeding and mortality. Treatment with steroids and antithyroid medications has been shown to be beneficial in correcting thrombocytopenia in these patients, although the response is varied. We report on a patient with Graves’ disease who presents with immune thrombocytopenic purpura.

Case presentation
A 37-year-old Ghanaian female presented to our hospital’s emergency department with a complaint of palpitations, difficulty breathing, easy fatigue, and headaches. She had been referred from a peripheral hospital as a case of thrombocytopenia, severe anemia, and anterior neck swelling. She was diagnosed with Graves’ disease 2 years ago, became euthyroid during treatment, but defaulted. On further examination and investigation, she was diagnosed with immune thrombocytopenic purpura and was also found to have elevated free T3 and T4, and suppressed thyroid stimulating hormone. She also had high thyroid autoantibodies. She was initially started on oral prednisolone but there was no stabilization of platelets until methimazole was introduced, which improved and normalized her platelet count.

Conclusion
The association of Graves’ disease with immune thrombocytopenic purpura, though documented, is uncommon, and very few cases have been reported thus far. There have not been any reported cases in Ghana or Sub-Saharan Africa and hence, clinicians should be aware of this association when investigating immune thrombocytopenic purpura and should consider Graves’ disease as a possible cause. From this study, we observed that there was no improvement in platelet count following the use of corticosteroid therapy until methimazole was started.
Whole genome sequencing to study antimicrobial resistance and RTX virulence genes in equine Actinobacillus isolates
Authors: Vereecke Nick , Vandekerckhove Arlette , Theuns Sebastiaan , Haesebrouck Freddy , Boyen Filip 
Published: April 2023

AbstractActinobacillus equuliis mostly associated with disease in horses and is most widely known as the causative agent of sleepy foal disease. Even though existing phenotypic tools such as biochemical tests, 16S rRNA gene sequencing, and Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) can be used to identify members of theActinobacillusgenus, these methods struggle to differentiate between certain species and do not allow strain, virulence, and antimicrobial susceptibility typing. Hence, we performed in-depth analysis of 24 equineActinobacillusisolates using phenotypic identification and susceptibility testing on the one hand, and long-read nanopore whole genome sequencing on the other hand. This allowed to address strain divergence down to the whole genome single nucleotide polymorphism (SNP) level. While lowest resolution was observed for 16S rRNA gene classification, a new multi-locus sequence typing (MLST) scheme allowed proper classification up to the species level. Nevertheless, a SNP-level analysis was required to distinguishA. equulisubspeciesequuliandhaemolyticus. Our data provided first WGS data onActinobacillusgenomospecies 1,Actinobacillus genomospecies 2, andA. arthritidis, which allowed the identification of a newActinobacillusgenomospecies 1 field isolate. Also, in-depth characterization of RTX virulence genes provided information on the distribution, completeness, and potential complementary nature of the RTX gene operons within theActinobacillusgenus. Even though overall low prevalence of acquired resistance was observed, two plasmids were identified conferring resistance to penicillin-ampicillin-amoxicillin and chloramphenicol in oneA. equulistrain. In conclusion our data delivered new insights in the use of long-read WGS in high resolution identification, virulence gene typing, and antimicrobial resistance (AMR) of equineActinobacillusspecies.
A class of Schrödinger elliptic equations involving supercritical exponential growth
Authors: Leuyacc Yony Raúl Santaria 
Published: April 2023

AbstractThis paper studies the existence of nontrivial solutions to the following class of Schrödinger equations: $$ \textstyle\begin{cases} -\operatorname{div}(w(x)\nabla u) = f(x,u),&\ x \in B_{1}(0), \\ u = 0,&\ x \in \partial B_{1}(0), \end{cases} $$

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Examining the effect of electronic banking service quality on customer satisfaction and loyalty: an implication for technological innovation
Authors: Ayinaddis Samuel Godadaw , Taye Birhan Ambachew , Yirsaw Bantie Getnet 
Published: April 2023

AbstractIn this ever-growing competitive banking industry, understanding the effect of electronic banking service quality on customers’ satisfaction and loyalty is the secret to being competitive and successful in the sector. In Ethiopia, measuring service quality in the banking sector is a new paradigm. The primary purpose of this research was to examine the effect of electronic banking (e-Banking) service quality on customer satisfaction in Ethiopia’s emerging banking industry. Data were obtained using a closed-ended structured questionnaire from a total of 385 participants selected using a convenience sampling technique. Frequencies, percentage distributions, group modes, standard deviations, Chi-square correlations, and multinomial logistic regression were employed to analyze the quantitative data. The results confirmed a significant effect of the variables responsiveness, reliability, security and privacy, speed, and convenience on customer satisfaction. Similarly, customer satisfaction with the electronic banking service quality has a significant effect on customer loyalty. System availability, easiness to use, and service charge, on the other hand, have no statistically significant impact on customer satisfaction. Hence, based on the findings of this study, it is recommended that banks should focus on the factors related to responsiveness, reliability, system availability, and speed to maximize customer satisfaction and loyalty. The adoption of electronic banking service that offers a meaningful guarantee takes care of problems promptly, provides services precisely as promised, is always available and quick delivery enables customers to be better satisfied and thus create committed and loyal customers.
The inter-connection of sports bra design attributes and elderly women's perceptions
Authors: Zhou Jie , Lei Qiwen Emma , Mao Qian , Wang Aosi , Yip Joanne , Zhang Jun 
Published: April 2023

AbstractAs a sports facility category, a sports bra is regarded as an enabling technology garment with advanced functions and new cultural meanings. Women, particularly elderly women, are encouraged to wear a sports bra during physical activity because wearing a sports bra can not only prevent them from exercise-induced injuries but also increase the acceptance of their bodies. However, most studies usually targeted younger women. The requirements and expectations of elderly women on sports bras differ from younger individuals. Hence, this study aims to advance and explore the design demands, providing insights into age-friendly sports bra design by using more permeable physical and psychological boundaries based on conceptual frameworks. The sports bra evaluation words were extracted and calculated to construct the network. The appearance frequency of keywords, closeness centrality, betweenness centrality, and interconnection between every pair of words were illustrated and analyzed by using semantic-based network analysis. Network analysis deduced that the discomfort of sports bras was closely related with the support, tightness, cup design, and strap design. Beside, thermal management contributes significantly to the comfort. The outlook of a sports bra was associated with cup design. The Page-rank result showed that cup, tightness, hot, straps and quality were the top five important design attributes. The unobservable mechanisms underlying the keywords provide an alternative model, which can help to explore the key improvements for sports bra design.
Incidence of non-invasive all-cause pneumonia in children in the United States before and after the introduction of pneumococcal conjugate vaccines: a retrospective claims database analysis
Authors: Hu Tianyan , Sarpong Eric M. , Song Yan , Done Nicolae , Liu Qing , Lemus-Wirtz Esteban , Signorovitch James , Mohanty Salini , Weiss Thomas 
Published: April 2023

Abstract
Background
Pneumonia is the most serious form of acute respiratory infection and Streptococcus pneumoniae is a leading cause of pediatric bacterial pneumonia. Pneumococcal conjugate vaccines were introduced in the United States (US) in 2000 (7-valent [PCV7]) and 2010 (13-valent [PCV13]). This study estimated annual incidence rates (IRs) of all-cause pneumonia (ACP) among US children aged < 18 years before and after the introduction of PCV7 and PCV13.

Methods
ACP episodes were identified in the IBM MarketScan Commercial and Medicaid Databases using diagnosis codes. Annual IRs were calculated overall and by inpatient and outpatient settings as the number of episodes per 100,000 person-years (PY) for all children aged < 18 years and by age group (< 2, 2–4, and 5–17 years). National estimates of annual pneumonia IRs were extrapolated using Census Bureau data. Interrupted time series (ITS) analyses were used to assess immediate and gradual changes in monthly pneumonia IRs, adjusting for seasonality.

Results
In the commercially-insured population, ACP IRs declined between the pre-PCV7 period (1998–1999) and late PCV13 period (2014–2018) from 5,322 to 3,471 episodes per 100,000 PY for children aged < 2 years, from 4,012 to 3,794 episodes per 100,000 PY in children aged 2–4 years but increased slightly from 1,383 to 1,475 episodes per 100,000 PY in children aged 5–17 years. The ITS analyses indicated significant decreases in monthly ACP IRs in the early PCV7 period (2001–2005) among younger children and in the early PCV13 period (2011–2013) among all children. Increases were observed in the late PCV7 period (2006–2009) among all age groups, but were only significant among older children. IRs of inpatient ACP decreased across all age groups, but outpatient pneumonia IRs remained stable during the study timeframe, even increasing slightly in children aged 5–17 years. More prominent declines were observed for Medicaid-insured children across all age groups; however, Medicaid IRs were higher than IRs of commercially-insured children during the entire study timeframe.

Conclusions
ACP disease burden remains high in US children of all ages despite overall reductions in incidence rates during 1998–2018 following the introduction of PCV7 and PCV13.
Novel Lyapunov-based rapid and ripple-free MPPT using a robust model reference adaptive controller for solar PV system
Authors: Manna Saibal , Akella Ashok Kumar , Singh Deepak Kumar 
Published: April 2023

AbstractThe technological, economic, and environmental benefits of photovoltaic (PV) systems have led to their widespread adoption in recent years as a source of electricity generation. However, precisely identifying a PV system's maximum power point (MPP) under normal and shaded weather conditions is crucial to conserving the maximum generated power. One of the biggest concerns with a PV system is the existence of partial shading, which produces multiple peaks in the P–V characteristic curve. In these circumstances, classical maximum power point tracking (MPPT) approaches are prone to getting stuck on local peaks and failing to follow the global maximum power point (GMPP). To overcome such obstacles, a new Lyapunov-based Robust Model Reference Adaptive Controller (LRMRAC) is designed and implemented to reach GMPP rapidly and ripple-free. The proposed controller also achieves MPP accurately under slow, abrupt and rapid changes in radiation, temperature and load profile. Simulation and OPAL-RT real-time simulators in various scenarios are performed to verify the superiority of the proposed approach over the other state-of-the-art methods, i.e., ANFIS, INC, VSPO, and P&O. MPP and GMPP are accomplished in less than 3.8 ms and 10 ms, respectively. Based on the results presented, the LRMRAC controller appears to be a promising technique for MPPT in a PV system.
Contested Flights
Authors: Kavesh Muhammad A. 
Published: April 2023

Abstract
Despite the invention and sophistication of drones and unarmed aerial vehicles, satellites, and more recently, cyber espionage, “spy pigeons” remain a serious threat at the India-Pakistan border. The entanglement between flying pigeons for “sport” and capturing pigeons for “espionage” is critical to construe multiple meanings of more-than-human border intrusion in South Asia. Such an incursion not only endangers long-standing values of human-pigeon companionship but also moots a perplexity of intrusion that lies between the ethical acceptance of the more-than-human intruders and necessary resistance to their hostile infiltration. Explored through the geopolitically complex experiences of intrusion that have shaped the India-Pakistan relationship since Partition, intruding spy pigeons provide a critical perspective on distrust, animosity, and espionage in South Asia.
An Atomic Age Unleashed
Authors: Kramer Derek J. 
Published: April 2023

Abstract
While tens of thousands of Koreans were subject to the atomic attacks on Hiroshima and Nagasaki, early peninsular analysis of the bombings rarely grappled with the existence of these individuals. The general exclusion of colonial subjects from the story of the atomic bombings has long been identified as part of a nationalization of the wartime years, a move that situates the history of the attacks as a specifically Japanese experience. Less understood is how postcolonial intellectuals in Korea encouraged this historiographical trend. Across the peninsula, a common commitment to the idea of science as emancipatory enabled postcolonial Korean writers to conflate political liberation with advancements in the field of atomic science. This fusion of postcolonial developmentalism and atomic scientism, common in both the North and the South between 1945 and 1950, drowned out the critical temporalities introduced by peninsular survivors of the atomic attacks. This article outlines the historiographical obstacles Korean bomb victims posed to emancipatory accounts of the attacks. Postcolonial bomb victims were interpolated into a postwar community that was physiologically unable to leave the fact of the bombings in a colonial past.
Building a Public Culture of Pandemic Storytelling
Authors: Yang Guobin , Moses Adetobi 
Published: April 2023

AbstractFrom the very beginning of the COVID-19 pandemic, ordinary people around the world have been documenting their experiences in diverse media forms, giving rise to a public culture of pandemic storytelling. This public culture, however, can be transitory. Personal stories may disappear for many reasons. The authors call for scholars to help build and sustain this public culture through the work of digital archiving and research, and the authors emphasize a descriptive imperative, as opposed to theorizing, as the more urgent course of action.
Parking Search in the Physical World: Calculating the Search Time by Leveraging Physical and Graph Theoretical Methods
Authors: Dutta Nilankur , Charlottin Thibault , Nicolas Alexandre 
Published: April 2023

Parking plays a central role in transport policies and has wide-ranging consequences: While the average time spent searching for parking exceeds dozens of hours per driver every year in many Western cities, the associated cruising traffic generates major externalities, by emitting pollutants and contributing to congestion. However, the laws governing the parking search time remain opaque in many regards, which hinders any general understanding of the problem and its determinants. Here, we frame the problem of parking search in a very generic, but mathematically compact formulation that puts the focus on the role of the street network and the unequal attractiveness of parking spaces. This problem is solved in two independent ways, valid in any street network and for a wide range of drivers’ behaviours. Numerically, this is done by means of a computationally efficient and versatile agent-based model. Analytically, we leverage the machinery of Statistical Physics and Graph Theory to derive a generic mean-field relation giving the parking search time as a function of the occupancy of parking spaces; an expression for the latter is obtained in the stationary regime. We show that these theoretical results are applicable in toy networks as well as in complex, realistic cases such as the large-scale street network of the city of Lyon, France. Taken as a whole, these findings clarify the parameters that directly control the search time and provide transport engineers with a quantitative grasp of the parking problem. Besides, they establish formal connections between the parking issue in realistic settings and physical problems. Funding: This work was supported by IDEXLYON (IDEXLYON 2020–2021); Institut Rhonalpin des Systèmes Complexes (IXXI) (Vulnerabilite). Supplemental Material: The e-companion is available at https://doi.org/10.1287/trsc.2023.1206 .
Scorpion envenomation-associated myocarditis: A systematic review
Authors: Fereidooni Reza , Shirzadi Saeedreza , Ayatizadeh Seyyed Hamidreza , Bahloul Mabrouk , Tavangar Amirali , Zomorodian Seyed Alireza , Roshanshad Amirhossein , Ardekani Ali 
Published: April 2023

Background
Scorpion envenomation is associated with several complications. One of the most serious complications is the cardiac involvement in the form of myocarditis that remains the main reason for mortalities associated with scorpion envenomation. The present review aims to elucidate clinical and paraclinical findings associated with scorpion-related myocarditis, and to explore different management strategies and subsequent outcomes.

Methods
We searched PubMed, Web of Science, Scopus, and Google Scholar for articles related to keywords of myocarditis associated with scorpion envenomation up to May 1, 2022. Each article was carefully reviewed by two independent researchers. In case of disagreement for inclusion, we sought a third researcher opinion.

Results
A total of 703 cases from 30 case reports and 34 case series were included in our review. Myocarditis associated with scorpion envenomation was usually reported in children presenting with cardiopulmonary symptoms including pulmonary edema (60.7%) and shock or hypotension (45.8%). The most common ECG findings are sinus tachycardia (82%) followed by ST-T changes (64.6%). The management typically included inotropes (especially dobutamine), prazosin, diuretics, nitroglycerine and digoxin, when indicated. Mechanical ventilation was required in 36.7% of the patients. Mortality in confirmed scorpion-related myocarditis cases is estimated at 7.3%. Almost all survived cases showed rapid recovery and improvement in the left ventricular function.

Conclusion
Even though myocarditis associated with scorpion envenomation is rare, it remains a serious and in some of cases a fatal consequence of scorpion sting. In case of relative presentations, particularly in envenomed children, diagnosis of myocarditis should be considered. Early screening using serial cardiac markers and echocardiography can guide the treatment. Prompt treatment that focuses on cardiogenic shock and pulmonary edema usually results in a favorable outcome.
A novel integrative multi-omics approach to unravel the genetic determinants of rare diseases with application in sinusoidal obstruction syndrome
Authors: Waespe Nicolas , Mlakar Simona Jurkovic , Dupanloup Isabelle , Rezgui Mohamed Aziz , Bittencourt Henrique , Krajinovic Maja , Kuehni Claudia E. , Nava Tiago , Ansari Marc 
Published: April 2023

BackgroundGenotype-phenotype analyses of rare diseases often suffer from a lack of power, due to small sample size, which makes identifying significant associations difficult. Sinusoidal obstruction syndrome (SOS) of the liver is a rare but life-threatening complication of hematopoietic stem cell transplantation (HSCT). The alkylating agent busulfan is commonly used in HSCT and known to trigger SOS. We developed a novel pipeline to identify genetic determinants in rare diseases by combiningin vitroinformation with clinical whole-exome sequencing (WES) data and applied it in SOS patients and controls.MethodsFirst, we analysed differential gene expression in six lymphoblastoid cell lines (LCLs) before and after incubation with busulfan. Second, we used WES data from 87 HSCT patients and estimated the association with SOS at the SNP and the gene levels. We then combined the results of the expression and the association analyses into an association statistic at the gene level. We used an over-representation analysis to functionally characterize the genes that were associated with a significant combined test statistic.ResultsAfter treatment of LCLs with busulfan, 1708 genes were significantly up-, and 1385 down-regulated. The combination of the expression experiment and the association analysis of WES data into a single test statistic revealed 35 genes associated with the outcome. These genes are involved in various biological functions and processes, such as “Cell growth and death”, “Signalling molecules and interaction”, “Cancer”, and “Infectious disease”.ConclusionsThis novel data analysis pipeline integrates two independent omics datasets and increases statistical power for identifying genotype-phenotype associations. The analysis of the transcriptomics profile of cell lines treated with busulfan and WES data from HSCT patients allowed us to identify potential genetic contributors to SOS. Our pipeline could be useful for identifying genetic contributors to other rare diseases where limited power renders genome-wide analyses unpromising.Trial registrationFor the clinical dataset: Clinicaltrials.gov:NCT01257854.https://clinicaltrials.gov/ct2/history/NCT01257854.