bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of Land Surface Albedo Changes over Iran using Remote Sensing Data
Authors: Motlagh Omid Reza Kefayat , Darand Mahmmad 
Published: April 2023

Abstract
Albedo is one of the key parameters in climatic studies. Investigating its temporal and spatial behavior can be a tool for understanding environmental changes. The MODIS sensor continuously produces the land surface albedo on a global scale and with the appropriate spatial resolution and makes it available to researchers. In this study, to analyze Iran’s surface albedo trend, first, the daily albedo data of the MODIS on Iran in the period from 1/1/2001 to 12/30/2021 with a spatial resolution of 500 meters was prepared from the NASA website. After the necessary pre-processing, the long-term seasonal and annual trend of Iran's albedo was calculated at the 90% confidence level using the non-parametric Mann-Kendall test. The findings showed that the albedo trend is positive in the lowland interior areas of Iran and negative in the highland areas. Since the decreasing trend of albedo in highland areas indicates the reduction of snow cover in these areas, this issue can challenge the life and water resources of these areas that rely on the accumulation of snow.
Simultaneous determination of paracetamol, propyphenazone, aspirin and caffeine in white wine samples by liquid chromatography-triple quadrupole tandem mass spectrometry
Authors: Han Dan , Ding Yongliang , Peng Kun , Tang Bobing , Xi Cunxian , Den Anping Den Anping 
Published: April 2023

Abstract

A highly sensitive liquid chromatography-triple quadrupole tandem mass spectrometry (LC-MS/MS) for simultaneous determination of analgesic-antipyretics drugs, e.g. paracetamol (PC), propyphenazone (PZ), aspirin (AS) and caffeine (CF), in white wine samples was presented. The chromatographic separation was carried out on a narrow C18column by a gradient elution using acetonitrile (A) and 10 mM ammonium acetate with 0.1% formic acid (B) as the solvents at a flow rate of 0.3 ml/min. Qualitative and quantitative analysis of PC, PZ and CF were achieved by multiple reaction monitoring (MRM) in positive mode, while the analysis of AS was completed by MRM in negative mode. Under optimal conditions, good linearity with high correlation coeﬃcient (>0.9981) were obtained between 0.05-50 ng mL-1for PC, 0.005-20 g mL-1for PZ, 0.3-200 g mL-1for AS, and 1.0-50 g mL-1for CF. The limit of detection (LOD) values of the method for PC, PZ, AS and CF were found to be 0.015, 0.0015, 0.08 and 0.25 g mL-1, respectively. Spiking experiments revealed good recoveries in range of 87.6~111.0% with relative standard deviations (RSD) of 2.1~9.4%. Total 1006 white wine samples were collected and analyzed by the proposed method. PC was found in three inferior white wines samples, and the residual levels of PC, PZ, AS and CF in other samples were undetectable. It was demonstrated that the proposed LC–MS/MS is a powerful analytical tool for sensitive determination of PC, PZ, AS and CF in white wine samples.
Significance of dumpsites for the conservation of bird fauna in Afar region, Ethiopia
Authors: Tesfahunegny Weldemariam , Assefa Alembrhan 
Published: April 2023

AbstractBackground:Dumpsites have a significant role for the attraction of diverse species of wildlife including birds. This study was carried out to assess the significance of dumpsites for the conservation of birds in Afar region, Ethiopia from August, 2019 to March, 2020, covering both the wet and dry seasons. Nine dumpsites found in different towns of Afar region were selected. Point count technique was employed to identify and count the birds. Shannon-Weiner diversity index was used to estimate species diversity and Two-way ANOVA was used to test birds’ species richness and abundance variation across dumpsites and seasons.Results: A total of 48 bird species consisting of one endemic and 10 globally threatened species were recorded. Red-billed Quelea, Marabou Stork and Egyptian Vulture were the most abundant species. Variation in bird species richness and abundance among dumpsites was significant (F = 8.44, df = 8, P < 0.05) and F = 15.507, df = 8, P< 0.05), respectively. Moreover, significant seasonal variation in abundance was also observed (F = 19.339, df = 1, P< 0.05). The highest species diversity (H’ = 3.18) was observed during wet season in Abala and Afambo dumpsites and the highest species evenness (E = 0.86) was observed during dry season in Afdera.Conclusion: Bird species diversity and abundance among the dumpsites was high, and man-made disturbance in these sites are main threats for conservation of birds. Therefore, conservation measures are needed to maintain the survival of this unique bird diversity. Moreover, proper management of dumpsites is vital to support the waste dependent birds.
Depth resolved thermal wave imaging approach for non-destructive testing and evaluation of steel sample
Authors: Arora Vanita , Mulaveesala Ravibabu , Dua Geetika 
Published: April 2023

Abstract
Reliability of sub-surface defects is imperative for safer functionality of critical materials/components/structures used in a wide variety of applications in various industries. The need for reliable, fast, remote, safe inspection and evaluation methods for detecting hidden defects increases in parallel with the demand for more sustainable solutions, which helps in inherent design and manufacturing specifications modifications. During in-service operations, the hidden defects are typically originated from various loading conditions leading to catastrophic failure. This work explores the best possible reliable, fast, remote, and safe inspection and evaluation experimental method and the associated post-processing approach using InfraRed Imaging (IRI) for Thermal Non-Destructive Testing and Evaluation of mild steel materials. This proposed work provides an insight into the state-of-the-art research in the field of thermal/infrared non-destructive testing and evaluation methods and associated post processing approach to visualize the hidden subsurface defects not only resolved by spatial thermal gradients but also simultaneously provide temporal thermal gradients at the defective regions.
Comparison of the efficacy and safety of biosimilar adalimumab injection with innovator adalimumab in subjects with active ankylosing spondylitis
Authors: S Chandrashekara , Parida Jyoti Ranjan , Sonawale Archana , Sharma Vishnu , Basu Kaushik , Mathew John , Dharmapalaiah Chethana , Bhatia Girish , Seth Gaurav , Kakade Girish , Jain Neeraj , Sharma Reena , Fatima Firdaus , Srivast Rajeshwar Nath , Shah Romi , Desai Bankim , Nalawade Ajit , Haridas Vikram , Kumar Uma , Naidu R , Pawar Roshan , Aiwale Amol , Rane Yogesh , Shahavi Vinayaka , Sharma Akhilesh 
Published: April 2023

Abstract
Objectives
To compare the efficacy and safety of biosimilar adalimumab injection manufactured by Enzene Biosciences Ltd. with innovator adalimumab (iADA, HUMIRA®) in subjects with active ankylosing spondylitis (AS).
Methods
The prospective, multicenter, randomized, double-blind, phase III study involved 192 subjects with active AS recruited at 20 centers across India. The subjects who fulfilled the eligibility criteria were randomized in a ratio of 2:1 (i.e.,125 subjects in biosimilar adalimumab arm and 67 subjects in the iADA arm). The selected subjects received both the investigational products at a dose of 40 mg subcutaneously (pre-filled syringe contained 40 mg adalimumab in 0.4 ml as the active ingredient) every other week for a total of 12 weeks. Efficacy assessment was done based on ASAS response criteria. Safety assessment was based on complete physical examination, adverse event (AE) monitoring, vital signs, ECG, anti-adalimumab antibody (ADA) assessment, and laboratory tests.
Results
At 12 weeks, the ASAS 20/40/70 responses were achieved by 97.5%, 94.1%, and 68.9% patients who received biosimilar injection as compared to 98.4%, 96.7%, and 77% patients in iADA arm. Safety assessment showed that 19 (15.2%) subjects reported 33 AEs in the biosimilar adalimumab arm and 8 (11.9%) subjects reported 11 AEs in iADA arm. ADA for positive and negative subjects was statistically non-significant (P 0.3516) between the two arms.
Conclusion
The ASAS 20/40/70 response rates at week 12 were equivalent between patients treated with biosimilar adalimumab injection manufactured by Enzene Biosciences Ltd and those treated with iADA. Both the drugs had comparable safety and tolerability profiles.
Trial registry name: The Clinical Trials Registry- India (CTRI),
URL: http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=42640&EncHid=&userName=enzene
Trial registration no: no. CTRI/2020/09/028070
Pointwise slant lightlike submanifold with semi-Riemannian screen distribution
Authors: Srivast Sachin Kumar , Dhiman Mayrika , Sood Kanika 
Published: April 2023

Abstract
We generalize the study of pointwise slant lightlike submanifolds of indefinite cosymplectic manifold. We prove the existence of semi-Riemannian screen distribution when the rank of radical is less than the index of a manifold and give a generalized definition of pointwise slant lightlike submanifolds. Also, we have constructed examples showing timelike components in screen distribution and derived the condition for pointwise slant lightlike submanifolds, which helps to conclude various related results. We studied pointwise slant lightlike submanifolds under different conditions, like totally umbilical and minimal lightlike, and obtained results.
Mathematical Subjclass Classfication(2020): 53C12, 53C25, 53B25, 53B30, 53D10.
Impact of Comminution Kinetic Energy: First Mathematical Modeling of Fragmentation Dynamic Fractures Per Millimetre of Coal
Authors: Nasution Lukman Hakim , Mursito Anggoro Tri , Astuti Widi , Nurjaman Fajar , Prasetyo Erik , Birawidha David Candra , Amin Muhammad , Haryono Tri , Wicaksono Mahruri Arif , Sumardi Slamet , Susanti Diah , Bahfie Fathan 
Published: April 2023

Abstract
The various aspects of coal, including its chemical composition, properties, and environmental impacts. The recent research focused on developing new technologies and processes to improve the efficiency and effectiveness of coal comminution, with a particular focus on the use of kinetic energy impact application of coal comminution with linear momentum. We explored the potential benefits of this approach, as well as ongoing research aimed at optimizing the comminution process and improving our understanding of the physics of coal comminution. Ultimately, the goal of this research is to reduce energy consumption and environmental impact associated with coal mining and use. From calculation on comminution of coal samples 10 mm long, 1 mm thick and 1 mm wide using linear momentum kinetic impact energy were carried out to produce coal between 100 mm and 1 mm in size. The main parameters of the process are the configuration of the impact surface of the runway wall, volume, mass and initial size of the sample, as well as the impact distance to the runway. The results of the analysis produce 55 process equations with models per millimetre scale; starting from the equation. The value of the kinetic energy of the fragmentation impact is increasing small if the distribution of energy has an increasing impact Far from static center impact; following with bigger size fragment. With doubling the value of the distribution of impact kinetic energy per millimetre; uniformity size fragment between 100mm to 1mm reached. This first mathematical model is expressed as a comminution dynamic fragmentation linear pattern per millimetre.
Research on the mechanism of miR-132-3p in inhibiting the proliferation、invasion and metastasis of colon cancer by targeted regulation of PDGF
Authors: Li Chaobin , Lu Kemei , Lang Cuicui , LI Min , Yang Chenggang 
Published: April 2023

Abstract
Objective: To investigate the impacts of miR-132-3p on the proliferation, apoptosis, metastasis and invasion of colon cancer cells by targeted regulation of PDGF, so as to provide a new approach and target for studying the development mechanism of colon cancer and targeting gene therapy of colon cancer.
Methods: qRT-PCRexperiment was used to detect the expression of miR-132-3p between colon cancer tissue and adjacent tissue.CCK-8 cloning experiment was carried out to observe the results of overexpressed miR-132-3p HCT-116 cells proliferation; Flow cytometry experiment was conducted to examine the results of apoptosis;Transwell chamber experiment and scratch healing experiment were performed to detect the effect of cell invasion and metastasis; Pearson correlation analysis was adopted to evaluate the correlation between miR-132-3p and PDGF;Luciferase experiment was used to detected the luciferase activity;qRT-PCR and Western blot were carried out to detect the PDGF mRNA and protein respectively;Tumorigenesis experiment was conducted in nude mice to verify the inhibitory effect of miR-132-3p on colon cancer HCT-116 cells.
Results: Compared with the pericarcinomatous tissues, the expression of miR-132-3p in colon cancer tissue decreased significantly (P<0.05); Compared with the miR-NC group, the proliferation and invasive ability of HCT-116 cells in the miR-132-3pmimic group decreased significantly (P<0.05); The luciferase activity in the wild-type miR-132-3p-mimic group was lower than that in the miR-132-3pNA group obviously(P<0.05);Compared with miR-132-3pmimic+vector group, the proliferation and invasion ability of cells in miR-132-3pmimic+PDGF group increased apparently (P<0.05);Compared with miR-132-3pNC group, the subcutaneous tumor mass in the nude mice in miR-132-3pmimic group was smaller (P<0.05).
Conclusion: PDGF is the action target of miR-132-3p. miR-132-3p can inhibit the proliferation, invasion and metastasis of colon cancer cells by controlling the expression of PDGF so as to promote the apoptosis of colon cancer cells.
Putamen volume as a predictor of repetitive and restricted behaviors and interests related intensity in autism
Authors: Lefebvre Aline , Traut Nicolas , Pedoux Amandine , Maruani Anna , Beggiato Anita , Elmaleh Monique , Germanaud David , Amestoy Anouck , Moal Myriam Ly-Le , Chatham Christopher , Murtagh Lorraine , Bouvard Manuel , Alisson Marianne , Leboyer Marion , Bourgeron Thomas , Toro Roberto , Dumas Guillaume , Moreau Clara , Delorme Richard 
Published: April 2023

Abstract
Background. Repetitive and restricted behaviors and interests (RRBI) are core symptoms of autism with a complex entity and are commonly categorized into ‘motor-driven’ and ‘cognitively-driven’. RRBI symptomatology depends on the individual’s clinical environment limiting the understanding of RRBI physiology, particularly their associated neuroanatomical structures. The complex RRBI heterogeneity needs to explore the whole RRBI spectrum by integrating the clinical context (autistic individuals, their relatives and typical developing (TD) individuals). We hypothesized that different RRBI dimensions would emerge by exploring the whole spectrum of RRBI, and that these dimensions are associated with neuroanatomical signatures - involving cortical & subcortical areas.
Method. A sample of 792 individuals composed of 267 autistic subjects, their 370 first-degree relatives and 155 TD individuals was enrolled in the study. We assessed the whole patterns of RRBI in each individual by using the Repetitive Behavior Scale-Revised and the Yale-Brown Obsessive Compulsive Scale. We estimated brain volumes using MRI scanner for a subsample of the subjects (n=152, 42 ASD, 89 relatives and 13 TD). We first investigated the dimensionality of RRBI by performing a principal component analysis on all items of these scales and included all the sampling population. We then explored the relationship between RRBI-derived factors with brain volumes using linear regression models.
Results. We identified 3 main factors (with 30.3% of the RRBI cumulative variance): Factor 1 (FA1, 12.7%) reflected mainly the ‘motor-driven’ RRBI symptoms; Factor 2 and 3 (respectively 8.8% and 7.9%) gathered mainly Y-BOCS related items and represented the ‘cognitively-driven’ RRBI symptoms. These three factors were significantly associated with the right/left putamen volumes but with opposite effects: FA1 was negatively associated with an increased volume of the right/left putamen conversely to FA2 & FA3 (all uncorrected p<0.05). FA1 was negatively associated with the left amygdala (uncorrected p<0.05), and FA2 was positively associated with the left parietal structure (uncorrected p=0.001).
Conclusion. Our results suggested 3 coherent RRBI dimensions involving the putamen commonly and other structures according to the RRBI dimension. The exploration of the putamen’s integrative role in RSBI needs to be strengthened in further studies.
WITHDRAWN: Seasonal variation of the quality of groundwater resources for human consumption and industrial purposes in the Central Plain Zone of Punjab, India
Authors: Singh Gobinder , Wani Owais Ali , Egbueri Johnbosco C. , Salaria Amit , Singh Harinder 
Published: April 2023

Abstract
Due to environmental pollution, climate change and anthropogenic activities, the judicious use and quality of groundwater for industrial, agricultural, and drinking purposes had garnered a lot of attention. In order to access the seasonal suitability of groundwater on the basis of hydrochemistry and different indices, 196 groundwater samples were collected and analysed for different physicochemical parameters. The results revealed that only 1.02 percent of water samples from pre and post monsoon season exceeded the permissible limits of WHO and BIS guidelines for suitability of drinking water. The TDS content was also within the permissible limits with mean value of 523.7 and 565.6 mg/L for pre and post monsoon seasons, respectively. The concentration of Ca2+, Mg2+ were within the permissible limits whereas chloride content (29.1% and 15.3% during pre and post monsoon period, respectively) exceeds the permissible limits. The sulphate ion concentration (mean value of 0.46 meq L-1) also ranged between the permissible limits. Based upon water quality index (WQI), none of the water sample was unfit for drinking purpose whereas synthetic pollution index (SPI) categorized all the samples as moderately polluted during both the seasons. For industrial purpose suitability, the various indices i.e., LSI (39.8 and 30.6 % have high corrosive tendency during pre and post monsoon, respectively), CSMR (98.4 and 100 % have tendency for galvanic corrosion during pre and post monsoon, respectively) and aggressive index (49.5% were severely corrosive during pre-monsoon period) showed quite variable results. Moreover, only 1.0 per cent of the total water samples seem to be strongly affected by salinization during pre-monsoon period.
Swelling Kinetics of Acrylamide Grafted Polysaccharides Blend Hydrogel
Authors: Sayed Marwa M. El , sorour mohamed , Shaalan Hayam 
Published: April 2023

Abstract
Hydrogel of polysaccharides blend graft acrylamide (PsB-g-Am) has been synthesized by copolymerization based on a free radical reaction using potassium persulfate (KPS) initiator and methylenebisacrylamide (MBA) as a crosslinking agent under nitrogen atmosphere. The polysaccharides blend (PsB) composed of starch, chitosan and alginate. The produced hydrogels structure have been characterized using FTIR spectroscopy and X-ray diffraction (XRD). Swelling water ratio (SWR) in distilled water for grafted and hydrolyzed hydrogel with different Am/PsB weight ratios have been studied. Maximum obtained SWR was 140 g/g using Am/PsB weight ratio of 0.96. The present work is also addressed a preliminary study for the swelling kinetics of the produced hydrogel. It was found that, the swelling kinetics obeys first-order kinetics.
Characterization of hybrid nanofibrils composed of xyloglucan and disintegrated bacterial cellulose
Authors: Tagawa Satomi , Tokuyasu Ken , Yamagishi Kenji , Ike Masakazu , Amano Yoshihiko , Mizuno Masahiro 
Published: April 2023

Abstract
Nata puree (NP)—obtained by disintegrating nata de coco (bacterial cellulose [BC]) using a household blender—can be combined with tamarind seed gum (TG) to generate NPTG. In this study, BC fibrils (BC-TG) were prepared by removing free TG from NPTG and characterized. BC-TG exhibited high water dispersibility and relatively long nanofibrils (> 20 µm). We examined the distribution of xyloglucan, the main component of TG, on BC nanofibrils using immunofluorescence staining with calcofluor white, which stains the hydrophilic cellulose surface, and found that xyloglucan was adsorbed at different sites along the fibers. This indicated that BC-TG was a composite nanofibril of xyloglucan and BC. Furthermore, BC-TG showed a higher degree of adsorption on hydrophobic plastic substrates than BC did, suggesting a change in the surface properties of BC. Because the BC-TG preparation process is simple, requires only water and raw materials, and does not involve chemical reactions, it is expected to be an environmentally friendly method for the preparation and modification of BC nanofibrils.
Environmental geochemical characteristics of selenium in Northeastern China 1
Authors: Dai Huimin , Savin Igor , Zhang Yihe , Liang Shuai , Cui Yujun , Chen Chaoqun , Liu Kai , Zhao Hongmei , Ma TingtaoMa , Song Yunhong 
Published: April 2023

Abstract
Keshan Disease (KD) is still a serious endemic public health problem in Northeast China. Previous studies have mainly focused on soil selenium content, staple food selenium content, and human selenium level, but there are few systematic studies on soil selenium existing forms and their migration from soil to crops and human body. In order to provide visualization of the spatial distribution characteristics and migration status of soil selenium content, and to provide a reference basis for the etiological analysis, prevention, control and elimination of KD, the 121183 topsoil soil (0-20 cm) geochemical data and 30295 soil parent material data which were collected and analysed by two-layer gridding method were used to infer the barrier factors in the migration and transformation of selenium from soil to crop and human body. The total selenium average of soil, staple food and human body be counted, the soil selenium existing forms and the correlation analysis between soil aluminum trioxide, iron trioxide were analysed.The average content of topsoil selenium in Northeast China was 0.20 mg/kg, which was significantly lower than the world soil selenium content average (0.4 mg/kg) and slightly lower than the Chinese soil selenium content average (0.239 mg/kg).The average selenium content of human hair is only 0.16mg/kg in Baiquan, Heilongjiang Province. Soil-forming parent material has some influence on soil selenium content, however, epigenetic enrichment is a more significant enrichment factor on soil selenium content. Soil selenium existing in humic acid state selenium, strongly organic bound state selenium, and the contents of selenite, selenate and methyl selenocysteine which are easily used by plants are all relatively high, correlation analysis between soil selenium content and organic matter, iron and aluminium oxides shows that soil organic matter and iron and aluminium oxides were the main barrier factors for selenium migration and transformation. Lower soil selenium content may be the basic factor for the biogeochemical deficiency of selenium, the sequestration of selenium by clay chemical constituents such as iron and aluminium oxides and soil organic matter is the direct factor for the biogeochemical low selenium in the Northeastern China, which increasing the risk of KD in the population. These research findings can provide more evidence to assess the elimination of biogeochemical aetiology of diseases from a selenium nutrient perspective.