bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D printing of continuous cellulose fibre composites: microstructural and mechanical characterisation
Authors: Touchard Fabienne , Marchand Damien , Chocinski-Arnault Laurence , Fournier Teddy , Magro Christophe 
Published: July 2023

Purpose
Additive manufacturing is a recent technology used in the production of composite materials. The use of continuous fibres as reinforcement is necessary to achieve high mechanical performance. However, making these materials more environmentally friendly is still challenging. The purpose of this study was to investigate the feasibility of 3D printing a composite made of continuous regenerated cellulose fibres using a standard 3D printer generally used for printing polymers.

Design/methodology/approach
The production process was based on a pre-impregnated filament made from a tape containing continuous cellulose fibres and Pebax® matrix. 3D printed composite samples were fabricated using fused deposition modelling. The tape, filament and 3D printed composites were first analysed by means of modulated differential scanning calorimetry and micrography. Tensile tests were then performed, and the mechanical characteristics were determined at each step of the production process. Fracture surfaces were investigated by field-emission gun–scanning electron microscopy.

Findings
Results showed that the mechanical behaviour of the material was maintained throughout the production process, and the 3D printed biocomposites had a stiffness equivalent to that of traditionally manufactured continuous cellulose fibre composites. The obtained 3D printed composites showed an increase in strength value by a factor of 4 and in tensile modulus by a factor of 20 compared to those of unreinforced Pebax® polymer.

Originality/value
This paper demonstrates the feasibility of 3D printing composites based on continuous cellulose fibres, paving the way for new biocomposites made by additive manufacturing.
Effects of binder droplet size and powder particle size on binder jetting part properties
Authors: Rahman Kazi Moshiur , Miyanaji Hadi , Williams Christopher B. 
Published: July 2023

PurposeIn binder jetting, the interaction between the liquid binder droplets and the powder particles defines the shape of the printed primitives. The purpose of this study is to explore the interaction of the relative size of powder particles and binder droplets and the subsequent effects on macro-scale part properties.Design/methodology/approachThe effects of different particle size distribution (5–25 µm and 15–45 µm) of stainless steel 316 L powders and droplet sizes (10 and 30 pL) on part density, shrinkage, mechanical strength, pore morphology and distribution are investigated. Experimental samples were fabricated in two different layer thicknesses (50 and 100 µm).FindingsWhile 15–45 µm samples demonstrated higher green density (53.10 ± 0.25%) than 5–25 µm samples (50.31 ± 1.06%), higher sintered densities were achieved in 5–25 µm samples (70.60 ± 6.18%) compared to 15–45 µm samples (65.23 ± 3.24%). Samples of 5–25 µm also demonstrated superior ultimate tensile strength (94.66 ± 25.92 MPa) compared to 15–45 µm samples (39.34 ± 7.33 MPa). Droplet size effects were found to be negligible on both green and sintered densities; however, specimens printed with 10-pL droplets had higher ultimate tensile strength (79.70 ± 42.31 MPa) compared to those made from 30-pL droplets (54.29 ± 23.35 MPa).Originality/valueTo the best of the authors’ knowledge, this paper details the first report of the combined effects of different particle size distribution with different binder droplet sizes on the part macro-scale properties. The results can inform appropriate process parameters to achieve desired final part properties.
How did sustainable Spanish and Italian brands communicate COVID-19 on social media?
Authors: Zarco Carmen , Robles Alberto , Valls-Prieto Javier , Cordon Oscar 
Published: July 2023

Purpose
This study aims to determine how the most sustainable brands in Italy and Spain developed communication and awareness-raising actions during the COVID-19 pandemic and whether these companies were truly involved in raising public awareness of the pandemic. The authors specifically focus on sustainable companies, as health communication is considered to be an important corporate social responsibility task.

Design/methodology/approach
To answer these questions, the authors have used data on the social media activity (Twitter and Instagram) of these brands in Spain and Italy, extracting the posts and associated hashtags that each of them has published throughout the pandemic to be processed using social network analysis and visualization techniques.

Findings
The detailed analysis of both the levels of activity and the content of the messages provides interesting insights into the communication models of the companies and the influence of factors such as time, country and the specific social media platform used.

Originality/value
The authors analyze the communication of the most sustainable businesses on social media during the pandemic, adopting a highly innovative approach. The particular originality of this study lies in the parallel analysis of two different countries that were simultaneously shaken by the pandemic in very similar circumstances. This study also presents a novel use of graphical representation tools in terms of companies’ behavior for health communication on social media.
Effectiveness of treatment options for tubal ectopic pregnancy: A systematic review and network meta‐analysis
Authors: Al Wattar Bassel H. , Solangon Sarah A. , de Braud Lucrezia V. , Rogozińska Ewelina , Jurkovic Davor 
Published: July 2023

AbstractBackgroundTubal ectopic pregnancy (TEP) is a common gynaecological emergency. Several medical and surgical treatment options exist, but it is not clear which is the safest and most effective treatment.ObjectivesTo compare the effectiveness of expectant, medical and surgical treatment options for TEP using a systematic review and network meta‐analysis.Search StrategyMEDLINE, EMBASE, and CENTRAL from inception till September 2022.Selection CriteriaRandomised trials that evaluated any treatment option for woman with a TEP.Data Collection and AnalysisWe performed pairwise and network meta‐analyses using a random effect model. We assessed the studies' risk of bias, heterogeneity and network inconsistency. We reported primarily on TEP resolution and treatment failure using relative risk (RR) and 95% confidence‐intervals (CI).Main ResultsWe included 31 randomised trials evaluating ten treatments (n = 2938 women). Direct meta‐analysis showed no significant benefit for using methotrexate compared to expectant management for TEP resolution. Network meta‐analysis showed similar effect‐size for most conservative treatment options compared to expectant management for TEP resolution (glucose intra‐sac instillation vs. expectant RR 0.84, 95% CI 0.63–1.12; methotrexate intra‐sac instillation vs. expectant RR 0.91, 95% CI 0.75–1.10; multi‐dose methotrexate vs. expectant RR 1.00, 95% CI 0.88–1.15; prostaglandin intra‐sac instillation vs. expectant RR 0.75, 95% CI 0.53–1.07; salpingotomy vs. expectant RR 0.99, 95% CI 0.84–1.16; single dose methotrexate vs. expectant RR 0.97, 95% CI 0.85–1.10; single dose methotrexate + mifepristone vs. expectant RR 1.09, 95% CI 0.89–1.33). All treatment options showed a higher risk of failure compared to salpingectomy.ConclusionsThere is insufficient evidence to support the use of any medical treatment option for TEP over expectant management.
Current status and temporal trend in incidence, death, and burden of esophageal cancer from 1990−2019
Authors: Mazidimoradi Afrooz , Banakar Niloofar , Khani Yousef , Allahqoli Leila , Salehiniya Hamid 
Published: July 2023

AbstractBackgroundEsophageal cancer (EC) is one of the world's most unknown and deadly cancers. This study aimed to provide updated epidemiological indicators and the recent trend of EC by age group, gender, and geographical region in the world.MethodsAnnual case data and age‐standardized rates (ASRs) of epidemiological indicators of EC were collected from the 2019 Global Burden of Disease (GBD) study from 1990 to 2019 in 204 countries and territories based on the sociodemographic index (SDI). Relative difference (%), average annual percentage change (AAPC), and the male/female ratio were calculated. Data are reported in values and 95% confidence interval (CI).ResultsEC age‐standardized incidence rates (ASIR) decreased by 19%, age‐standardized death rates (ASDR) decreased by 25%, and disability‐adjusted life‐years ASR (DALYs ASR) decreased by 30% from 1990 to 2019. The higher number of EC cases was in men aged 50 to 69 years and in women aged over 70. From 1990 to 2019, Middle SDI countries experienced a decline in the ASIR and ASDR of EC. The High SDI countries had an increasing ASDR trend. In World Bank High‐Income countries, the ASIR of EC has remained unchanged and decreased in other regions. The Asia continent has the highest rate of incidence, mortality, and burden of EC and the highest rate of reduction. East Asia, Southern Sub‐Saharan Africa, and Eastern Sub‐Saharan Africa respectively have the highest ASIR of EC. Central Asia has experienced the greatest decrease in the ASIR and ASDR of EC, the countries of Central Europe had a steady ASIR and High‐Income North America had an increasing trend in ASIR and ASDR. The burden of EC shows a decreasing trend worldwide. Central and East Asia regions have the highest rate and the highest increase in the burden of EC.ConclusionBased on great variation in the geographical distribution of epidemiological indicators of EC, investigating the reasons for this diversity requires more studies to be conducted in the field of prevention, distribution of risk factors, and implementation of screening methods with high cost‐effectiveness, and access to treatment methods. The provision of regional solutions may be more effective than global strategies.
Understanding the impacts of childhood adversity on sleep problems in children with fetal alcohol spectrum disorder: A comparison of cumulative and dimensional approaches
Authors: Chandler‐Mather Ned , Betts Joseph , Donovan Caroline , Shelton Doug , Dawe Sharon 
Published: July 2023

AbstractBackgroundThe developmental impacts of prenatal alcohol exposure (PAE) and postnatal exposure to adversity are typically considered in isolation. However, both contribute independently to sleep problems. Children with fetal alcohol spectrum disorder (FASD) have PAE and significant sleep disturbances. What is not clear is the relative contribution to these disturbances of exposure to early life adversity. This study examined how exposure to such adversity impacts frequent insomnia symptoms and nightmares in children with FASD and “At Risk” designations.MethodsWe compared two approaches to modeling adversity in children who had undergone a diagnostic assessment for FASD: a cumulative risk approach that sums adversities to create a total score and an approach that treats exposure to threat and deprivation as independent dimensions. Data on caregiver‐reported exposure to adversity and sleep problems for 63 children (aged 3 years 4 months to 7 years 8 months) were extracted from clinical archives. Cumulative risk, threat exposure, and deprivation exposure scores were computed and were tested as predictors of insomnia symptoms and nightmares. All analyses controlled for age and gender.ResultsThere were high rates of caregiver‐reported sleep problems with 60.3% (n = 38) of children having nightmares and 44.4% (n = 28) having a frequent insomnia symptom. The cumulative risk analysis showed that for every additional exposure to adversity, the odds of having a caregiver‐reported insomnia symptom increased by 38%. The dimensional analysis showed no relationship between deprivation and sleep problems. However, every additional exposure to threat increased the odds of nightmares by 93%.ConclusionsExposure to postnatal adversity contributes to sleep disturbances in children with FASD, with unique roles for cumulative risk and the threat dimension of adversity. The implications of these findings for the etiology and treatment of sleep disturbances in children with FASD are discussed.
Exploring opportunities for drug repurposing and precision medicine in cannabis use disorder using genetics
Authors: Greco Laura A. , Reay William R. , Dayas Christopher V. , Cairns Murray J. 
Published: July 2023

AbstractCannabis use disorder (CUD) remains a significant public health issue globally, affecting up to one in five adults who use cannabis. Despite extensive research into the molecular underpinnings of the condition, there are no effective pharmacological treatment options available. Therefore, we sought to further explore genetic analyses to prioritise opportunities to repurpose existing drugs for CUD. Specifically, we aimed to identify druggable genes associated with the disorder, integrate transcriptomic/proteomic data and estimate genetic relationships with clinically actionable biochemical traits. Aggregating variants to genes based on genomic position, prioritised the phosphodiesterase gene PDE4B as an interesting target for drug repurposing in CUD. Credible causal PDE4B variants revealed by probabilistic finemapping in and around this locus demonstrated an association with inflammatory and other substance use phenotypes. Gene and protein expression data integrated with the GWAS data revealed a novel CUD associated gene, NPTX1, in whole blood and supported a role for hyaluronidase, a key enzyme in the extracellular matrix in the brain and other tissues. Finally, genetic correlation with biochemical traits revealed a genetic overlap between CUD and immune‐related markers such as lymphocyte count, as well as serum triglycerides.
Sisterly intimacies: Islam, gift‐giving, and women's relations of care in Russia
Authors: Rabinovich Tatiana 
Published: July 2023

AbstractDrawing on ethnographic fieldwork in Saint Petersburg (Russia) between 2015 and 2016, this article weaves together gift exchange and affect theory to analyze how low‐income Muslim women cultivated sisterly intimacies, a materially mediated and affect‐laden form of attachment. Sustained through the practices of giving clothing, food, and other spiritually significant items to one another, sisterly intimacies illuminates not only how the women survived and thrived on the margins of Russian society amid socioeconomic crises and political volatility but also how their material exchanges facilitated their ability to remain continuously oriented toward their community and God while striving for an ethical Muslim life and a favorable afterlife. Sisterly intimacies as a cultural formation also offers a broader glimpse into the affective landscapes of Russia, where indignation about socioeconomic injustices and authoritarianism coexist with a desire for (religious) connectivity, ethical living, and collective world‐making. Sisterly intimacies as a mode of relationality and self‐making highlights the agentive capacity of intimacy to create worlds for those who struggle to live in ways that they consider meaningful.
Development and validation of a prognostic model for death 30 days after adult emergency laparotomy
Authors: Eugene N. , Kuryba A. , Martin P. , Oliver C. M. , Berry M. , Moppett I. K. , Johnston C. , Hare S. , Lockwood S. , Murray D. , Walker K. , Cromwell D. A. ,   the NELA Project Team
Published: July 2023

SummaryThe probability of death after emergency laparotomy varies greatly between patients. Accurate pre‐operative risk prediction is fundamental to planning care and improving outcomes. We aimed to develop a model limited to a few pre‐operative factors that performed well irrespective of surgical indication: obstruction; sepsis; ischaemia; bleeding; and other. We derived a model with data from the National Emergency Laparotomy Audit for patients who had emergency laparotomy between December 2016 and November 2018. We tested the model on patients who underwent emergency laparotomy between December 2018 and November 2019. There were 4077/40,816 (10%) deaths 30 days after surgery in the derivation cohort. The final model had 13 pre‐operative variables: surgical indication; age; blood pressure; heart rate; respiratory history; urgency; biochemical markers; anticipated malignancy; anticipated peritoneal soiling; and ASA physical status. The predicted mortality probability deciles ranged from 0.1% to 47%. There were 1888/11,187 deaths in the test cohort. The scaled Brier score, integrated calibration index and concordance for the model were 20%, 0.006 and 0.86, respectively. Model metrics were similar for the five surgical indications. In conclusion, we think that this prognostic model is suitable to support decision‐making before emergency laparotomy as well as for risk adjustment for comparing organisations.
Transmesenteric approach for laparoscopic endoscopic cooperative surgery for a duodenal adenoma located in the third portion of the duodenum
Authors: Muranaka Futoshi , Kitazawa Masato , Iwaya Yugo , Tokumaru Shigeo , Nakamura Satoshi , Koyama Makoto , Yamamoto Yuta , Hondo Nao , Soejima Yuji 
Published: July 2023

AbstractWe report our experience in a patient with adenoma located in the horizontal part of the duodenum, which was effectively treated with the transmesenteric laparoscopic endoscopic cooperative surgery (LECS) approach. This approach, which entails incising the mesentery of the colon, simplified laparoscopic access to the horizontal part of the duodenum, which was minimally mobilized. Thus, the bulb and descending part of the duodenum were fixed to the retroperitoneum, facilitating stable handling of the endoscope and enabled safe and effective excision of an adenoma located in the horizontal part of the duodenum. This approach enabled safe and effective excision of an adenoma located in the horizontal part of the duodenum. The advantages of this method include a secure field of view, lower probability of damage to large vessels, and minimizing the defect to the intestine caused by the incision.
Not all stakeholders are equal: Corporate social responsibility variability and corporate financial performance
Authors: Gao Yongqiang , Nie Yumeng , Hafsi Taïeb 
Published: July 2023

AbstractThe advocates of “doing well by doing good” have advised firms to invest in corporate social responsibility (CSR), but firms may get lost on how to invest their limited resources in it since CSR is a complex concept involving many activities and different types of stakeholders. In this work, we draw upon the perspective of stakeholder saliency and the stakeholder resource‐based view (SRBV) to propose that stakeholders may have different levels of expectations for CSR and contribute to firm value creation differently. Therefore, firms using different CSR to treat different stakeholders (high CSR variability) will have better financial performance. We further propose that context, in particular media coverage and state ownership, moderates the relationship between CSR variability and firm performance, as stakeholders of highly visible firms and state‐owned enterprises (SOEs) may frown upon a discriminate treatment in CSR. Findings based on a sample of 3313 publicly listed firms and 15,324 firm‐year observations in China's stock markets during the 2010–2018 period provide good support for our predictions.
Death: The asymmetry mystery
Authors: Goldman Alan H. 
Published: July 2023

AbstractAs the Roman philosopher Lucretius asked, why do we fear and regret death, but do not regret not having been born earlier, when death and prenatal nonexistence are mirror images? Both deprive us of goods we might have had, and this deprivation most plausibly explains the badness of death. This paper first considers and rejects explanations other than the deprivation of goods. It then suggests an explanation in terms of a state of which death deprives us, and which is itself asymmetrical in regard to the future and the past. This sharp asymmetry in this one very important good helps to justify the difference in our attitudes, especially among those for whom death approaches. The paper departs from the usual rigid format in which a philosopher says what she is going to say, then says it, and then repeats it. In matching form to mystery content, the missing clue to the solution will not be revealed until later in the paper.
Visual humanization of refugees: A visual rhetorical analysis of media discourse on the war in Ukraine
Authors: Martikainen Jari , Sakki Inari 
Published: July 2023

AbstractThis study examines how news images of refugees in the context of the war in Ukraine mobilize intergroup relations. A visual rhetorical analysis is used to examine the rhetorical strategies employed in news images of Ukrainian refugees in a mainstream Finnish national newspaper from February 25 to May 31, 2022. The data consisted of 465 images. The study constructed four humanizing visual rhetorical strategies based on the visual expression in news images: maternalizing, fragilizing, agonizing, and activizing. The rhetorical strategies constructed four subject positions for Ukrainian refugees: vulnerable victims, innocent victims, suffering Ukrainians, and persistent/resilient Ukrainians. All rhetorical strategies implicitly communicated the subject position of evil to Russia. The paper contributes to the current knowledge of the humanization of refugees in media discourse and the potential of media images to mobilize intergroup relations. Methodologically, the paper elaborates visual rhetorical analysis as a means of social psychological study of refugee discourse in the context of war.
Coptisine inhibits the malignancy of bladder carcinoma cells and regulates XPO1 expression
Authors: Li Jie , Liu Xiuheng 
Published: July 2023

AbstractThis work is performed to investigate the effect of coptisine (COP) on the malignant biological behaviors of bladder carcinoma cells and its underlying mechanism. Bladder carcinoma cell lines were treated with different concentrations of COP in vitro. Cell counting kit‐8 (CCK‐8), scratch healing assay, Transwell assay, and flow cytometry were used to detect cell growth, migration, invasion, and cell cycle progression. Bioinformatics analysis was performed to predict the molecular targets of COP. Quantitative real‐time PCR and western blot were adopted to determine the expression levels of exportin 1 (XPO1) mRNA and protein, respectively. Gene set enrichment analysis was applied to predict the signaling pathways related to XPO1. This study showed that COP treatment markedly suppressed the malignant biological behaviors of bladder carcinoma cells. XPO1 was identified as a downstream molecular target of COP in bladder carcinoma, and COP treatment inhibited the expression of XPO1 in bladder carcinoma cell lines. Overexpression of XPO1 reversed the impacts of COP on the malignant biological behaviors of bladder carcinoma cells. COP treatment modulated the expression level of cyclin D1 and CYP450 via XPO1. In summary, COP represses the malignant biological behaviors of bladder carcinoma cells and regulates XPO1 expression, which is promising to be a complementary drug for bladder carcinoma treatment.