bluuebunny/crossref_metadata_2025_split huggingface dataset:
The trend of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in spontaneous intracerebral hemorrhage and the predictive value of short-term postoperative prognosis in patients
Authors: Zhang Jian , Liu Chunlong , Hu Yaofeng , Yang Aoran , Zhang Yonghui , Hong Yang 
Published: May 2023

BackgroundNeutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) play an important role in the inflammatory response in various diseases, but the role in the course of spontaneous intracerebral hemorrhage (ICH) is unclear.MethodsThis study retrospectively collected baseline characteristics and laboratory findings, including NLR and PLR at different time points, from spontaneous ICH patients undergoing surgery between January 2016 and June 2021. Patients were scored using the modified Rankin Scale (mRS) to evaluate their functional status at 30 days post-operation. Patients with mRS score ≥3 were defined as poor functional status, and mRS score &lt;3 was defined as good functional status. The NLR and PLR were calculated at admission, 48 h after surgery and 3–7 days after surgery, respectively, and their trends were observed by connecting the NLR and PLR at different time points. Multivariate logistic regression analysis was used to identify independent risk factors affecting the prognosis of ICH patients at 30 days after surgery.ResultsA total of 101 patients were included in this study, and 59 patients had a poor outcome at 30 days after surgery. NLR and PLR gradually increased and then decreased, peaking at 48 h after surgery. Univariate analysis demonstrated that admission Glasgow Coma Scale (GCS) score, interval from onset to admission, hematoma location, NLR within 48 h after surgery and PLR within 48 h after surgery were associated with poor 30-day prognosis. In multivariate logistic regression analysis, NLR within 48 h after surgery (OR, 1.147; 95% CI, 1.005, 1.308; P, 0.042) was an independent risk factor for 30-day after surgery prognosis in spontaneous ICH patients.ConclusionIn the course of spontaneous intracerebral hemorrhage, NLR and PLR initially increased and subsequently decreased, reaching their peak values at 48 h after surgery. High NLR within 48 h after surgery was an independent risk factor for poor prognosis 30 days after surgery in spontaneous ICH patients.
Global DNA methylation and the association between metal exposure and chronic kidney disease
Authors: Hsueh Yu-Mei , Chen Wei-Jen , Lee Hui-Ling , Huang Ya-Li , Shiue Horng-Sheng , Hsu Sheng-Lun , Chen Hsi-Hsien , Lin Ying-Chin 
Published: May 2023

IntroductionPrior studies indicate that exposure to metals may alter DNA methylation. Evidence also shows that global DNA methylation is associated with chronic kidney disease (CKD). This study aimed to examine the association between CKD and 5-methyl-2-deoxycytidine (5mdC, %), a marker of global DNA methylation, and to evaluate the interaction between metal exposures and 5mdC (%) on CKD. We also explored the mediation effect of 5mdC (%) on the association between metal exposures and renal function (i.e., estimated glomerular filtration rate, eGFR).MethodsA total of 218 CKD patients and 422 controls were recruited in this case–control study. 5mdC (%), concentrations of blood lead and cadmium, plasma selenium, and total urinary arsenic were measured. CKD cases were clinically defined among patients with eGFR &lt;60 mL/min/1.73 m2 for at least 3 months and without hemodialysis. Odds ratio (OR) and 95% confidence interval (CI) were estimated by logistic regression models to examine the association between metal exposures, 5mdC (%), and CKD, adjusted for confounders. Multivariable linear regression models were used to examine associations between metal exposures, 5mdC (%), and eGFR.Results and DiscussionCKD cases compared to controls had 6.06-fold (95% CI: 3.11–11.81) higher odds of having high blood cadmium and high 5mdC (%) levels. A positive interaction on an additive scale was identified between blood cadmium and 5mdC (%) on CKD. Cases compared to controls had 4.73-fold (95% CI: 2.65–8.45) higher odds of having low plasma selenium and high 5mdC (%) levels; and a significant multiplicative interaction between plasma selenium and 5mdC (%) on CKD was observed. In addition, we found that blood lead and cadmium concentrations were positively associated, while plasma selenium concentrations were inversely associated, with 5mdC (%). The associations of blood lead and plasma selenium with eGFR were partially mediated by 5mdC (%). Our results suggest that 5mdC (%) may interact with plasma selenium and blood cadmium to influence the risk of CKD. The 5mdC (%) also potentially mediates the associations between exposure to metals and renal function.
Is there a change in the appropriateness of admission after patients were admitted? Evidence from four county hospitals in rural China
Authors: Chang Jingjing , Gao Hongxia , Su Dai , Li Haomiao , Chen Yingchun 
Published: May 2023

ObjectiveThis study aims to investigate the changes in admission appropriateness after patients were admitted and provide a reference for physicians to make admission decisions and for the supervision of medical service behavior by the medical insurance regulatory department.MethodsMedical records of 4,343 inpatients were obtained based on the largest and most capable public comprehensive hospital in four counties in central and western China for this retrospective study. The binary logistic regression model was employed to examine the determinants of changes in admission appropriateness.ResultsNearly two-in-thirds (65.39%) of the 3,401 inappropriate admissions changed to appropriate at discharge. Age, type of medical insurance, medical service type, severity of the patient upon admission, and disease category were found to be associated with the changes in the appropriateness of admission. Older patients (OR = 3.658, 95% CI [2.462–5.435]; P &lt; 0.001) were more likely to go from “inappropriate” to “appropriate” than younger counterparts. Compared with circulatory diseases, the case evaluated as “appropriate” at discharge was more frequent in the urinary diseases (OR = 1.709, 95% CI [1.019–2.865]; P = 0.042) and genital diseases (OR = 2.998, 95% CI [1.737–5.174]; P &lt; 0.001), whereas the opposite finding was observed for patients with respiratory diseases (OR = 0.347, 95% CI [0.268–0.451]; P &lt; 0.001) and skeletal and muscular diseases (OR = 0.556, 95% CI [0.355–0.873]; P = 0.011).ConclusionsMany disease characteristics gradually emerged after the patient was admitted, thus the appropriateness of admission changed. Physicians and regulators need to take a dynamic view of disease progression and inappropriate admission. Aside from referring to the appropriateness evaluation protocol (AEP), they both should pay attention to individual and disease characteristics to make a comprehensive judgment, and strict control and attention should be paid to the admission of respiratory, skeletal, and muscular diseases.
Retrieval of lunar polar heat flow from Chang’E-2 microwave radiometer and Diviner observations
Authors: Wei Guangfei , Li Xiongyao , Gan Hong , Shi Yaolin 
Published: May 2023

The internal heat flow related to the Moon’s composition, interior structure, and evolution history is not well-constrained and understood on a global scale. Up to now, only two in situ heat flow experiments, Apollo 15 and 17 were deployed nearly 50 years ago. The measured high values of heat flow might be influenced by lateral heat at highland/mare boundaries and enhanced by heat production from radioactive elements enriched unit, and may also be disturbed by astronauts’ activities. In this study, we proposed a new method to retrieve heat flows at two permanently shadowed craters, Haworth and Shoemaker of the Moon’s south pole, from Chang’E-2 microwave radiometer data and Diviner observations. Our results show that the average heat flow is 4.9 ± 0.2 mW/m2. This provides a constraint for the bulk concentration of Thorium within the lunar south polar crust 656 ± 54 ppb, which helps us understand the Moon’s thermal evolution and differentiation.
Nutrient intake, digestibility, performance, carcass traits and sensory analysis of meat from lambs fed with co-products of Amazon oilseeds
Authors: de Castro Vinicius Costa Gomes , Budel Juliana Cristina de Castro , Rodrigues Thomaz Cyro Guimarães de Carvalho , Silva Bruna Almeida , de Lima Alyne Cristina Sodré , de Souza Shirley Motta , da Silva Jamile Andréa Rodrigues , Joele Maria Regina Sarkis Peixoto , Silva André Guimarães Maciel e , Lourenço-Junior José de Brito 
Published: May 2023

Introduction:The increase in availability and nutritional composition of oilseed co-products has made it essential to study the use of this biomass.Methods:The objective of this work was to investigate the effects of including oilseed cakes on intake and digestibility, performance, carcass characteristics and meat sensory in feedlot lambs. Twenty-four crossbred Dorper × Santa Inês lambs, with initial body weight of 30 ± 1.3 kg, male, castrated, aged 4–5 months, were distributed in a completely randomized experimental design with four treatments (diets) and six replications (animals), confined in individual stalls for 70 days.Results:The inclusion of tucuma cake (Tuc) reduced dry matter intake (p &lt; 0.01) and diets with cupuassu cake (Cup) and palm kernel cake (Palm) reduced dry matter digestibility (p &lt; 0.05). The Tuc diet also provided the lowest final body weight (p = 0.02); lower average daily gain (p = 0.03); lower feed efficiency (p = 0.03) and lower carcass weight (p &lt; 0.01). However, diets did not influence carcass yield (%), fat thickness (mm) and loin eye area (cm2; p &gt; 0.05). Meat from lambs on the control diet was rated as less fibrous and more tender (p &lt; 0.05).Conclusion:The inclusion of tucuma cake does not influence digestibility, but reduces intake, performance and influences carcass characteristics and meat texture. Diets with cupuassu cake or palmiste cake reduced digestibility, however, intake, performance and carcass characteristics were similar to the control diet.
Analisis Perbandingan Dalam Menilai Tingkat Kesehatan Bank Dengan Menggunakan Metode CAMELS dan RGEC (Studi pada Bank Umum BUMN yang Terdaftar di BEI Periode 2017-2021)
Authors: Achmad Achmad , Faizul Muttaqin Anwar Musthofa Ahmad 
Published: May 2023

Banks as intermediary institutions have a very important role in driving the Indonesian economy, especially state-owned banks which are state-owned banks, so banks must be managed carefully and need special supervision from the government. This study was conducted with the aim of finding out how the soundness of state-owned banks is using the CAMELS and RGEC methods, as well as the point of difference between the two methods.
The type of research used is comparative descriptive with a quantitative approach. The data source used is secondary data. The data collection method in this research is library research and documentation study in the form of an annual report which is downloaded through the official website of the IDX (www.idx.co.id) and the official website of the company that is the subject of the research.
From the results of this study, it can be seen that the assessment of the soundness level of state-owned commercial banks using the CAMELS and RGEC methods has different results. The results of the recapitulation of the Health Level Assessment of BUMN Commercial Banks based on the CAMELS Method in the last 5 years show that the health conditions of Banks BRI, BNI and Bank Mandiri are in a "Very Healthy" condition. Meanwhile, Bank BTN is in a “Healthy” condition. Meanwhile, the results of the recapitulation of the Health Level Assessment of BUMN Commercial Banks based on the RGEC Method in the last 5 years show that the health conditions of Bank BRI and Bank Mandiri are in a "Very Healthy" condition. Meanwhile, Bank BNI and BTN are in a "healthy" condition. The difference in the assessment results from the two methods is because the CAMELS method is more focused on the upside side of the business, while the RGEC method is not only focused on the upside side of the business, but also covers the downside side of the business. So that the RGEC method is considered a more comprehensive bank soundness assessment solution.
Analisis Penentuan Harga Pokok Produksi Dengan Metode Full Costing, Variable Costing dan Activity Based Costing Pada Pabrik Air Minum Syifa’ P2S2 Sukorejo Situbondo
Authors: Pradipta Himawan , Wahedi Su'ud , Sihabuddin Endi 
Published: May 2023

The selling price is a crucial aspect of a product. Considering the selling price is one of the factors that will influence consumer decisions in buying a product. So that the determination of the selling price of the product must be done carefully and with integrated considerations. Through production costs, operational costs, desired profit targets, people's purchasing power, competitors' selling prices, general economic conditions, product price elasticity, and so on. The selling price policy is influenced by the cost of production and affects the success or failure of the company in achieving its goals.
Thus, the As-Syifa' Bottled Drinking Water Factory (AMDK), as one of the producers of drinking water circulating in the midst of the Sukorejo Islamic Boarding School environment, must carefully consider the method of determining the cost of production that is applied. Departing from this thought, the researcher intends to conduct research at As-Syifa's AMDK by applying the full costing method, variable costing, and activity based costing.
This research was conducted at Jln. KHR. Syamsul Arifin, Sukorejo village, Banyuputih, Situbondo. Precisely in one of the Islamic boarding school business units that produces drinking water. Data sources consist of primary and secondary sources. Data obtained through observation, interviews with managers, and documentation.
From the results of the discussion, the following conclusions are obtained: (1) the As-Syifa' AMDK factory has so far used the conventional method in determining its HPP and obtained a HPP of Rp. 9,612.- (2) from the results of applying the full costing method, variable costing, and activity based costing obtained by different HPP which can be taken into consideration by As-Syifa's AMDK manager.
Manfaat Penerapan Sistem Informasi Akuntansi Terhadap Kualitas Laporan Keuangan Bank Jatim Syariah Cabang Jember
Authors: Sunardi Sunardi , Tasliyah Nihayatut , Sa’adah Khalidatus 
Published: May 2023

The rapid development of information technology and computers. Encouraging companies to utilize ICT to support their business operations. Starting from planning, managing, controlling, evaluating, and presenting data and information to support decision-making activities. One of them is Bank Jatim Syariah through the implementation of an Accounting Information System called ESTIM. This system has the main function of managing all financial transactions and company financial reports online, real-time, and according to standards set by Bank Indonesia and the Financial Services Authority. This study aims to determine the benefits of implementing the SIA on the quality of financial reports. This qualitative descriptive research was conducted at the office of the Bank Jatim Syariah Jember Branch, with data sources from parties involved with the bank's AIS as primary data. The data was obtained through interviews and documentation. Then it is processed using qualitative data analysis method and its validity is tested by triangulation. The results of the study concluded that the implementation of the ESTIM system, as an accounting information system for Bank Jatim Syariah, provides many benefits for companies, especially in the aspects of online and realtime data storage and access, and is able to improve the quality of Bank Jatim Syariah financial reports to Bank Indonesia. Namely by presenting financial reports that are systematic, complete, accurate, fast, and have characteristics as reports that are reliable, relevant, understandable and comparable.
Analisis Pencatatan Akuntansi Pembiayaan Rahn (Gadai) di BMT. UGT. Sidogiri Capem. Banyuputih Situbondo Berdasarkan PSAK 107
Authors: Sukandi Sukandi , Shoimah Imroatus , Sa’diyah Halimatus 
Published: May 2023

Each Islamic financial institution may have a different strategy and operational system in order to increase the interest of its target consumers. It can be in the form of providing convenience to financing customers in terms of administrative requirements, but still carrying out strict selection and supervision to anticipate the risk of default (default). As is the case with BMT. UGT. Sidogiri in implementing rahn or mortgage financing. Another aspect is in terms of accounting records of transactions carried out by the company. Then, how is the accounting treatment applied in BMT. UGT. Sidogiri Capem. Banyuputih towards rahn financing. This qualitative descriptive research was carried out at the BMT sub-branch office. UGT. Sidogiri which is located in the Banyuputih sub-district, Situbondo. Data sources consist of primary and secondary data, which are collected through observation, interviews and documentation. As well as testing the validity of the data with triangulation. The conclusions obtained by the researcher are: that in terms of recognition, measurement, and presentation of rahn financing it is in accordance with PSAK 107. Meanwhile in terms of disclosure it is still not in accordance with PSAK 107.
Implementasi Pembiayaan Gadai Emas di BMT. UGT. Sidogiri Cabang Kangean Sumenep
Authors: Zakiyah Makhshushi , Anwar Zainul , Maila Maila 
Published: May 2023

Every Islamic financial institution has a varied marketing strategy to attract public interest. Both in terms of product and operational flow that is applied. As an Islamic financial institution that is not only profit-oriented, but also has a social mission to help those who are experiencing difficulties. BMT UGT Sidogiri prepares a financing product whose application is quite simple, namely the Sharia Gold Pawn (GES). So that the products are in great demand by the people of Kangean. This is what encourages researchers to find out how the GES financing product is implemented. This qualitative descriptive field research was conducted at BMT. UGT. Sidogiri Kangean Branch, using data obtained from primary and secondary data sources. Each field data was analyzed using a descriptive method and tested for its level of validity using triangulation (source) and observation extension methods. The conclusion obtained is that the implementation of BMT Sharia Gold Pawn financing. UGT. Sidogiri is in accordance with the terms and conditions. The application is easy, simple and fast, and is accompanied by rahn financing insurance.
Implementasi Pembiayaan Murabahah Bil Wakalah di PT. BPRS Bhakti Sumekar Cabang Pratama Ra’as Sumenep
Authors: Hamdi Ahmad , Rivqi Amin M. , Mursyid Mursyid 
Published: May 2023

As an intermediary institution, Islamic financial institutions (LKS) collect funds from the public through savings (savings), then channel them back to the community in the form of working capital and investment financing. One of the most dominant distributions of this financing is using a murabahah bil wakalah contract. As is the case with the BPRS Bhakti Sumekar Branch Pratama Ra'as. This study aims to find out in depth how the implementation of the contract in the field. Murabaha financing is the most dominant fund distribution scheme in LKS. Because it has a smaller risk for banks compared to implementing mudharabah and musyarakah contracts. This qualitative research uses data obtained from primary and secondary sources. Data is collected by observation, interview, and document methods. Any data that the researcher managed to collect, analyzed and tested its validity using source and method triangulation methods. The resulting conclusion is that the application of murabahah bil wakalah financing at BPRS Bhakti Sumekar Pratama Ra'as Branch is carried out with two contracts, namely starting with the wakalah contract first, then continuing with the murabahah contract. It's just that these two contracts are not set forth in their respective evidence, but are united in one contract agreement. This adaptation was made due to the efficiency and effectiveness aspects of time due to the limited number of BPRS personnel to serve the large number of financing customers.
Pengetahuan dan Sikap Peserta Didik Terhadap Pencegahan dan Pengendalian Covid-19
Authors: Lumbantoruan Sinta N. M. , Juslily Marta 
Published: May 2023

Covid-19 infection prevention and control (IPC) is needed to prevent the occurrence of cross infection among all healthcare workers including clinical dental students who are at high risk of being exposed to SARS-CoV-2 while doing their clinical care to patients. This study aimed to evaluate knowledge and attitude of dental students towards IPC during the Covid-19 pandemic. This was a descriptive and observational study with a cross-sectional design. A self-designed questionnaire was used as the measuring instrument already tested for validity and reliability and was distributed to 95 clinical dental students. The results showed that 61 respondents (64.2%) had good knowledge of IPC, 32 respondents (33.7%) had moderate knowledge, and two respondents (2.1%) had poor knowledge. There were 87.4% of respondents who had positive attitude in the sterilizing instrument aspect and 86.3% in the washing hand aspect. There were 42.1% of respondents that had negative attitude (42,1%) in the aspect of rinsing patients’ mouth with hydrogen peroxide. In conclusion, most clinical dental students have good knowledge towards Covid-19 IPC and positive attitude towards sterilizing instruments and hand hygiene as parts of the application of infection prevention and control.
Keywords: Covid-19; clinical dental students; infection prevention and control; knowledge; attitude

Abstrak: Pencegahan dan pengendalian infeksi (PPI) merupakan upaya mencegah terjadinya infeksi silang di seluruh fasilitas pelayanan oleh tenaga medis dan kesehatan di masa pandemi Covid-19, termasuk juga peserta didik Program Profesi Dokter Gigi yang memiliki risiko tinggi terpapar virus SARS-CoV-2 dalam melakukan kegiatan pendidikan dalam pelayanan kesehatan di bidang kedokteran gigi. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan dan sikap peserta didik Program Profesi Dokter Gigi terhadap PPI di masa pandemi Covid-19. Jenis penelitian ialah observasional deskriptif dengan desain potong lintang. Alat ukur yang digunakan berupa kuesioner yang dirancang dan telah dilakukan uji validitas dan reliabilitas. Hasil penelitian mendapatkan 95 peserta didik sebagai responden penelitian. Responden yang memiliki pengetahuan baik 61 orang (64,2%), cukup 32 orang (33,7%) dan kurang dua orang (2,1%). Peserta didik yang memiliki sikap positif tertinggi 87,4% pada aspek sterilisasi instrumen dan 86,3% pada aspek mencuci tangan sedangkan sikap negatif sebesar 42,1% pada aspek pasien berkumur dengan hidrogen peroksida. Simpulan penelitian ini ialah sebagian besar peserta didik Program Profesi Kedokteran Gigi memiliki pengetahuan baik terhadap PPI Covid-19 dan memiliki sikap positif pada pelaksanaan PPI untuk aspek sterilisasi instrumen dan kebersihan tangan.
Kata kunci: Covid-19; peserta didik Program Profesi Dokter Gigi; pencegahan dan pengendalian infeksi; pengetahuan; sikap