bluuebunny/crossref_metadata_2025_split huggingface dataset:
From fossil fuels to alternative fuels: strategy development for a sustainable transport sector in Germany
Authors: Vorwerg Franz Christian , Ebadi Torkayesh Ali , Venghaus Sandra 
Published: January 2025

Abstract

Background
Many countries agreed to reduce CO2 emissions to limit global warming under the terms of the Paris Agreement. In Europe, this agreement is supported by the climate targets introduced under the European Green Deal and the Fit for 55 package. Although Germany has made substantial progress in reducing emissions across various sectors, the transport sector remains a notable exception, showing little improvement. It is therefore essential to reevaluate the transport sector to strengthen its contribution to achieving the emission reduction targets. The aim of this study is to identify and propose strategies for shifting from fossil fuel-based transport to a more sustainable mode centred on alternative fuels. To investigate the potential pathways, an integrated approach is developed using a SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis and multi-criteria decision analysis (MCDA).

Results
A two-step survey was used to collect data from different stakeholders in order to derive the key factors for the implementation of alternative fuels and devise transition strategies. The findings show that reducing GHG emissions, resource competition, and the impacts of environmental regulations are the most important factors for evaluating the transition strategies. On the other hand, reducing the competitiveness of fossil fuels through increased prices, as well as technical and infrastructural support, are the most promising strategies.

Conclusions
The sustainable transition in the transport sector is fundamentally driven by the use of renewable fuel alternatives as sustainable energy carriers to replace fossil fuels. The use and deployment of renewable fuel alternatives will play the most significant role in the defossilization of the transport sector, on course to achieve a 55% reduction by 2030 and reaching climate-neutrality by 2050. However, identification of the proper transition strategies in the phase-out of fossil fuels and their replacement with renewable fuel alternatives necessitates a comprehensive evaluation framework. This work contributes to this by developing a holistic evaluation framework, enabling the incorporation of multiple stakeholders within the identification and evaluation of the transition strategies. While several strategies are identified, stakeholders agree that reducing the competitiveness of fossil fuels through increased prices and lower subsidies would be the best strategy.
Cascading effects of top predator changes in a seagrass bed under selective fishing
Authors: Chen Shixuan , He Qiang 
Published: January 2025

Abstract

Background
With the widespread promotion of selective fishing which may target top predatory fishes, the abundance and species composition of top predators could change, which may further impact species at lower trophic levels through a chain of cascading trophic interactions. However, the top-down effects of changes in predator communities driven by selective fishing remain poorly investigated.

Methods
Focusing on a seagrass ecosystem, we investigated how changes in two coexisting top predators (Lateolabrax japonicus and Acanthogobius ommaturus) under different selective fishing scenarios would affect species at lower trophic levels in a field manipulative experiment.

Results
We found that the trophic niches of A. ommaturus and L. japonicus overlapped greatly, although not completely. If loss of L. japonicus led to increases in A. ommaturus, the abundances of herbivorous benthos Barleeia bureri increased likely owing to A. ommaturus’s suppression of low-level predators, while epiphyte and seagrass biomass decreased significantly likely owing to A. ommaturus’s disturbance of seagrasses and sediments. If both predators were depleted, the biomasses of herbivorous benthos Cyclina sinensis and B. bureri increased significantly likely owing to the absence of top predators’ disturbance of sediments, while epiphyte and seagrass biomass did not change.

Conclusions
Our study showed that loss of one top predator could lead to rapid changes in species at lower trophic levels in seagrass beds, depending on changes in, and the trophic or non-trophic effects (including biological disturbances) of, its competitors. Therefore, in fisheries resource management, the ecological impacts of selectively fishing a target predator must be managed considering changes in, and the trophic or non-trophic effects of, its competitors where present.
Engagement in a web-based intervention for individuals who committed sexual offenses against children: observational study
Authors: Schröder Sonja , Tozdan Safiye , Briken Peer , Müller Jürgen L. , Fromberger Peter 
Published: January 2025

Abstract
Web-based interventions have been shown to be effective for various health and mental health problems. However, the effectiveness of interventions is often limited by the fact that individuals do not start or complete them. Using data from an intermediate analysis of the randomized placebo-controlled clinical trial to evaluate the effectiveness of @myTabu, the current study investigated engagement with a web-based intervention for 113 individuals convicted of child sexual abuse and/or for child sexual exploitation material. @myTabu is a human-supported, web-based intervention for individuals who have been convicted for sexual abuse of children or the use of child sexual exploitation material with the goal of reducing the risk factors for recidivism and actual recidivism. The results of the present study indicate that (a) 81% of the participants logged into the web-based intervention within 8 weeks after login credentials were sent; (b) there was a trend toward lower treatment readiness and lower belief in their own technical prerequisites in individuals who did not login; (c) 15% of the participants completed all requested sessions within the first 5 weeks of participation, and the average participant logged in on 6 different days and completed two sessions; (d) the number of login days and completed sessions could be predicted by treatment readiness. We discuss these findings and their implications for the development and implementation of further web-based interventions in the forensic context. Trial registration: German Clinical Trial Register (DRKS00021256). Prospectively registered 24.04.2020.
Three-dimensional quantitative temporomandibular joint changes in skeletal class I malocclusion treated with extraction and non-extraction protocols: a comparative study of fixed orthodontic appliances and clear aligners
Authors: Al-Somairi Majedh Abdo Ali , Zheng Bowen , Yang Xaiofeng , Zhang Yongxin , Alhammadi Maged S. , xu Hao , Alhashimi Najah , Almaqrami Bushra Sufyan , Al –Worafi Naseem Ali , Alyafrusee Enas Senan , Al-Tayar Barakat , Liu Yi 
Published: January 2025

Abstract

Objective
This study aimed to evaluate the positional and morphological changes in the temporomandibular joint (TMJ) in adult patients with skeletal Class I malocclusion treated with fixed orthodontic appliances (FAs) and clear aligners (CAs), both with and without premolar extractions.

Methods
This retrospective study involved 120 adult patients divided into non-extraction and extraction groups, each further subdivided equally into those treated with FAs and CAs. Cone beam computed tomography (CBCT) was used to assess the TMJ measurements before (T0) and after treatment (T1). Statistical analyses were conducted to compare the mean changes in intra- and inter-groups. A significance level of p ≤ 0.05 was considered.

Results
In the non-extraction group, specifically in FAs, significant increases were observed in TMJ parameters; anteroposterior condylar position (APCP) and mediolateral condylar inclination (MCI). Conversely, significant decreases were noted in vertical condylar position (VCP) and vertical condylar inclination (VCI). In the extraction group, significant increases were noted in APCP and anterior joint space (AJS), while posterior joint space (PJS) and anteroposterior condylar joint position (APCJP) decreased. For inter-group comparisons, the extraction group showed significant increases in APCP in FAs compared to CAs, and a significant decrease in APCJP in FAs compared to CAs.

Conclusion
FAs significantly impact condylar positions and joint spaces, especially in extraction cases. Monitoring TMJ parameters during orthodontic treatment is crucial to ensure positive outcomes and prevent TMJ disorders (TMDs). These findings may guide the selection of orthodontic appliances based on individual malocclusion characteristics.
Like objects or like subjects? Effects of student–robot interaction (SRI) and mathematical ability on students learning outcomes
Authors: Ojetunde Segun Michael , Ramnarain Umesh 
Published: January 2025

Abstract
Learning interaction patterns is key to the explanation of learning outcomes. Different studies have reported the relationship between classroom process variables and learning outcomes in a traditional classroom setting. However, the advent of robotics and its attendant student–robot interaction moderated by students’ mathematical ability is yet to be widely discussed empirically. This constitutes the major reason why the study investigated the effects of student–robot interaction and mathematical ability on students' learning outcomes, particularly among Nigerian high school students where the robotics curriculum is at the early stage of implementation. The study was anchored on engagement theory. A mixed-methods explanatory sequential Quant-dominant approach was adopted. A total of 327 high school students who have been exposed to robotic lessons from the year 2021 including robotics subject teachers and learning managers were sampled for the study. Data collected was analyzed using descriptive and inferential statistics alongside thematic analysis for qualitative data. It was found that mathematical ability could not moderate the relationship between student–robot interaction and learning outcomes (behavioural: β = − 0.001, t = 0.028, p > 0.05, Affective: β = 0.105, t = 0.316, p > 0.05, cognitive engagements: β = − 0.08, t = 0.316, p > 0.05). Affective engagements have a significant influence on critical thinking (β = .126, t = 3.19, p < 0.05) while both affective (β = 0.28, t = 5.63, p < 0.05) and cognitive (β = .17, t = 4.65, p < 0.05) engagements could predict students’ problem-solving. The conclusion was made that learning robotics is a potential instrument to develop students who can think critically to solve some long-standing problems in society. Furthermore, the process requires a lot of affective and cognitive engagement of the students, and in this regard, both parents and teachers have a role to play in offering support to students.
On the Effect of the Patient Table on Attenuation in Myocardial Perfusion Imaging SPECT
Authors: Huxohl Tamino , Patel Gopesh , Burchert Wolfgang 
Published: January 2025

Abstract

Background
The topic of the effect of the patient table on attenuation in myocardial perfusion imaging (MPI) SPECT is gaining new relevance due to deep learning methods. Existing studies on this effect are old, rare and only consider phantom measurements, not patient studies. This study investigates the effect of the patient table on attenuation based on the difference between reconstructions of phantom scans and polar maps of patient studies.

Methods
Jaszczak phantom scans are acquired according to quality control and MPI procedures. An algorithm is developed to automatically remove the patient table from the CT for attenuation correction. The scans are then reconstructed with attenuation correction either with or without the patient table in the CT. The reconstructions are compared qualitatively and on the basis of their percentage difference. In addition, a small retrospective cohort of 15 patients is examined by comparing the resulting polar maps. Polar maps are compared qualitatively and based on the segment perfusion scores.

Results
The phantom reconstructions look qualitatively similar in both the quality control and MPI procedures. The percentage difference is highest in the lower part of the phantom, but it always remains below 17.5%. Polar maps from patient studies also look qualitatively similar. Furthermore, the segment scores are not significantly different (p=0.83).

Conclusions
The effect of the patient table on attenuation in MPI SPECT is negligible.
Assessing the impact of sewage and wastewater on antimicrobial resistance in nearshore Antarctic biofilms and sediments
Authors: Clark Melody S , Gregson Benjamin H , Greco Carla , Nair Harisree Paramel , Clark Marlon , Evans Claire , Hughes Kevin A. , Hwengwere Kudzai , Leung Marcus , Peck Lloyd S , Walker Caray A. , Chow William 
Published: January 2025

Abstract

Background
Despite being recognised as a global problem, our understanding of human-mediated antimicrobial resistance (AMR) spread to remote regions of the world is limited. Antarctica, often referred to as “the last great wilderness”, is experiencing increasing levels of human visitation through tourism and expansion of national scientific operations. Therefore, it is critical to assess the impact that these itinerant visitors have on the natural environment. This includes monitoring human-mediated AMR, particularly around population concentrations such as visitor sites and Antarctic research stations. This study takes a sequencing discovery-led approach to investigate levels and extent of AMR around the Rothera Research Station (operated by the UK) on the Antarctic Peninsula.

Results
Amplicon sequencing of biofilms and sediments from the vicinity of Rothera Research Station revealed highly variable and diverse microbial communities. Analysis of AMR genes generated from long-reads Nanopore MinION sequencing showed similar site variability in both drug class and resistance mechanism. Thus, no site sampled was more or less diverse than the other, either in the biofilm or sediment samples. Levels of enteric bacteria in biofilm and sediment samples were low at all sites, even in biofilm samples taken from the station sewage treatment plant (STP). It would appear that incorporation of released enteric bacteria in wastewater into more established biofilms or associations with sediment was poor. This was likely due to the inactivation and vulnerability of these bacteria to the extreme environmental conditions in Antarctica.

Conclusions
Our results suggest minimal effect of a strong feeder source (i.e. sewage effluent) on biofilm and sediment microbial community composition, with each site developing its unique niche community. The factors producing these niche communities need elucidation, alongside studies evaluating Antarctic microbial physiologies. Our data from cultivated bacteria show that they are highly resilient to different environmental conditions and are likely to thrive in a warmer world. Our data show that AMR in the Antarctic marine environment is far more complex than previously thought. Thus, more work is required to understand the true extent of the Antarctic microbiota biodiversity, their associated resistomes and the impact that human activities have on the Antarctic environment.
The paradox of resource-richness: unraveling the effects on financial markets in natural resource abundant economies
Authors: Imran Muhammad , Khan Muhammad Kamran , Wahab Salman , Ahmed Bilal , Jijian Zhang 
Published: January 2025

Abstract
In the contemporary global landscape, understanding the nexus between financial inclusion and natural resource abundance is crucial, especially for resource-rich nations. This study uses diagnostic tests and method of moments quantile regression to examines this interplay across Australia, Brazil, Canada, China, India, Russia, and the United States. We find that achieving financial inclusion is significantly challenging for countries that heavily rely on natural resources. Diversified income sources and equitable wealth distribution are essential to mitigate these challenges. Additionally, we identify a positive correlation between economic development and financial inclusion, highlighting the mutually reinforcing relationship between growth and inclusivity. Our research also reveals a notable link between adopting renewable energy and improving financial inclusion, suggesting that environmental responsibility and financial accessibility are intertwined. Foreign direct investment has nuanced impacts on financial inclusion, adding depth to our understanding. Overall, stable income from natural resources and diversified economic development emerge as key promoters of financial inclusion. These insights advocate for regionally specific policies and lay a solid foundation for future research and informed policymaking that address financial inclusion challenges and advance sustainable development.

Graphical abstract
Therapeutic potential of 4-hexylresorcinol in reducing sarcopenia in diabetic masseter muscle
Authors: Gaida Dhouha , Park Young-Wook , Kang Yei-Jin , Kim Seong-Gon 
Published: January 2025

Abstract

Background
This study aimed to evaluate the effects of 4-hexylresorcinol (4HR), a synthetic compound with antioxidant and stress-modulating properties, on diabetic sarcopenia in the masseter muscle.

Methods
A controlled, parallel-arm study was conducted using 38 Sprague–Dawley rats divided into diabetic and non-diabetic groups. Diabetes was induced with streptozotocin (STZ), and the groups were further subdivided to receive weekly subcutaneous injections of either 4HR or saline. Muscle volume was assessed using micro-computed tomography (μCT), and glycogen storage and protein expression were analyzed using periodic acid-Schiff (PAS) staining and immunohistochemistry.

Results
μCT analysis revealed that diabetic rats exhibited significantly reduced masseter muscle volume compared to non-diabetic rats. However, 4HR treatment partially mitigated muscle volume loss in diabetic animals. Histological analysis showed higher PAS staining intensity in the diabetic group treated with 4HR compared to the untreated diabetic group, suggesting improved glycogen storage. Immunohistochemistry demonstrated that 4HR treatment significantly increased Glut4 and phosphorylated AMPKα (p-AMPKα) expression in diabetic muscle, indicating enhanced glucose uptake and metabolic activity.

Conclusions
4HR effectively alleviates diabetes-induced sarcopenia by preserving muscle volume, enhancing glycogen storage, and upregulating Glut4 and p-AMPKα expression. These findings suggest that 4HR holds potential as a therapeutic agent for combating muscle wasting in diabetes.
A digital platform for automated analysis of 1H NMR data: prototype framework of digital reference standard
Authors: Paudel Sunil Babu , Nam Joo-Won , Garcia Gonzalo R. Malca , Shapiro Ben , Laatikainen Pekka , Liu Yang 
Published: January 2025

Abstract
This study introduces an innovative approach to automatically analyzing 1H nuclear magnetic resonance (NMR) data, integrating a quantum mechanical spectral analysis (QMSA) to enhance efficiency over manual data analysis in NMR. This proposed digital platform features a standardized quantitative NMR (qNMR) procedure, digital Reference Spectra within a spectral library, and a visualized interactive interface for streamlined, automated NMR data analysis. This digital platform significantly reduces the need for manual intervention and shows promise in using spectral fitting to compare the calculated spectrum derived from a digital Reference Spectrum with an experimental spectrum. The digital platform excels in processing data of both single chemical and mixture, delivering accurate results, and positioning it as an essential tool for automatic 1H qNMR analyses. Case studies highlight the digital platform’s effectiveness, demonstrating its wide-ranging applicability. This shows that the proposed digital platform, based on a qNMR-based QMSA approach, offers reliable qualitative and quantitative analyses and paves the way for integrating digital reference standards into future compendial tests.

Graphical Abstract
Prevalence and pattern of skin disorders among children living in orphanages in Fayoum and Giza governorates, Egypt
Authors: Mohamed Noha Ezzat , Abdel-Wahed Wafaa Yousif , Gomaa Shimaa Mohammed , Hosny Mai Ashraf 
Published: January 2025

Abstract

Background
Childhood is a crucial period that shapes a person’s growth and development. For orphans, a lack of familial support affects their upbringing, making orphanages crucial for care. Children living in orphanage centers are vulnerable to several conditions, including dermatological disorders, due to factors such as malnutrition, overcrowding, and poor hygiene. The current study was carried to determine the prevalence and patterns of skin disorders among orphan children in Egypt, and to identify associated risk factors among orphans in Egypt.

Methods
A cross-sectional study was conducted among 415 children aged 1–18 years living in orphanage centers in Fayoum and Giza governorates, Egypt.

Results
Among the children, 77.1% had at least one skin disorder, with noninfectious conditions being more prevalent than infectious conditions (67.4 vs. 24.3%). The most common noninfectious conditions were dermatitis/eczema, pigmentary disorders, skin appendage disorders, and psycho-cutaneous issues. Fungal infections were the most common infectious condition. There was a significant relationship between hygiene and the type of skin disorder.

Conclusion
The prevalence of skin diseases in orphanages in Egypt is relatively high and is dominated by noninfectious skin diseases, and the prevalence of psycho-cutaneous disorders is high among these children. Comprehensive care strategies focusing on improving hygiene and emotional support and preventing abuse are essential for reducing the incidence of skin disorders and enhancing the overall health of orphaned children.