bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN TINGKAT PENGETAHUAN DAN PERSEPSI AKAN KEJADIAN PASCA IMUNISASI DENGAN KESEDIAAN MELAKSANAKAN VAKSINASI BOOSTER COVID-19 PADA MAHASISWA UNIVERSITAS LAMPUNG
Authors: Oktarlina Rasmi Zakiah , Rahmadani Letifa , Tjiptaningrum Agustyas , Carolia Novita 
Published: June 2023

COVID-19 adalah penyakit yang yang disebabkan oleh virus SARS-CoV-2 yang sangat menular. World Health Organization (WHO) telah menetapkan penyakit COVID-19 sebagai pandemi global. Vaksinasi COVID-19 terdiri dari pemberian primer dan booster yang berperan untuk menanggulangi penyebaran penyakit ini. Penelitian analitik observasional dilakukan untuk mengetahui hubungan antara tingkat pengetahuan serta persepsi akan kejadian pasca imunisasi terhadap kesediaan melaksanakan vaksinasi booster COVID-19 pada mahasiswa Universitas Lampung. Data didapatkan dengan menggunakan kuesioner dan diolah dengan analisis bivariat dengan menggunakan uji Chi-square. Penelitian ini menunjukkan terdapat hubungan antara tingkat pengetahuan dan persepsi akan kejadian pasca imunisasi dengan kesediaan melaksanakan vaksinasi booster dengan nilai p 0.006 dan 0.001.
Tingkat Pengetahuan dan Sikap Masyarakat Terhadap Pencegahan Penyakit Demam Berdarah di Desa Gla Dayah Kecamatan Krueng Barona Jaya Kabupaten Aceh Besar
Authors: Raisah Putri , Rahmayanti Yuni , Zahara Hafni , Nurmila Nurmila 
Published: June 2023

ABSTRAK Demam Berdarah Dengue (DBD) merupakan satu dari sekian banyak penyakit infeksi yang disebabkan oleh gigitan nyamuk Aedes aegypti yang banyak ditemui di daerah yang beriklim tropis dan subtropis di seluruh dunia. Penyakit ini dapat terjadi sepanjang tahun dan menyerang setiap individu tanpa memandang umur. penyakit ini muncul berkaitan dengan kondisi lingkungan dan perilaku masyarakat. Untuk mengetahui pengetahuan dan sikap masyarakat tentang pencegahan penyakit demam berdarah dengue DBD di Desa Gla Dayah Kecamatan Krueng Baronna Jaya Kabupaten Aceh Besar. Penelitian ini berjenis kuantitatif dengan desain analitik cross sectional. Populasi adalah semua masyarakat di Desa Gla Dayah Kecamatan Krueng Barona Jaya sebanyak 690 orang. Sampel penelitian yaitu 74 orang. Teknik pengambilan sampel dengan cara random sampling, data dianalisis dan diuji dengan menggunakan uji chi-square dengan nilai p ≤ 0.05. Menunjukkan responden yang berpengetahuan baik sebanyak 51 (68,9%) dan responden yang berpengetahuan kurang baik sebanyak 23 (31,1%). Kemudian responden yang memiliki sikap baik sebanyak 52 (70,3%) dan responden yang memiliki sikap kurang baik sebanyak 22 (29,7%). Ada hubungan pengetahuan dan sikap masyarakat terhadap pencegahan penyakit DBD di Desa Gla Dayah Kecamatan Krueng Barona Jaya Kabupaten Aceh Besar. Kata Kunci: Pengetahuan, Sikap, Pencegahan Penyakit Demam Berdarah Dengue DBD
Pemanfaatan Daun Beluntas (Pluchea Indeca) sebagai Deodoran Penurun Intensitas Bau dan Anti Iritasi: Literature Review Article
Authors: Dewi Siska Ratna , Widiyaningsih Andini , Pangestu Anjani Dwi , Amara Aisha Nusaiba , Wulandari Amalia , Setiawati Devi , Yuniarsih Nia 
Published: June 2023

ABSTRACT Beluntas leaves (Pluchea indeca) is one of the plants that is often used as a traditional medicine which contains antimicrobial substances to fight various bacteria. The leaves can be used in deodorants, cosmetic products containing antiseptics to preserve or reduce damage caused by bacteria so as to control body odor. The method used is the library research method, namely the method of collecting, reading and storing library materials and processing research materials by searching databases of various scientific articles. The purpose of the study was to analyze how beneficial the leaves are in reducing the intensity of body odor. The results of the examination showed that the leaves contained 17.78-19.02%, 98.25 mg/100 g of vitamin C and 2.55 g/100 g of carotene, and the chemical content of the leaves included alkaloid compounds (0.316%), flavonoids (4 , 18). ). ). %), tannins (2351%), essential oil 4.47%, phenol, chlorogenic acid, sodium, calcium, magnesium and phosphorus, can be used as products that can fight epidermal staphylococcal bacteria. Keywords: Beluntas Leaves, Deodorant, Smell Removal, Natural Materials. ABSTRAK Daun beluntas (Pluchea indeca) merupakan tumbuhan yang sering digunakan dalam pengobatan bahan alam, karenabeluntas mengandung zat antibakteri terhadap berbagai jenis bakteri. Daun beluntas dapat digunakan dalam deodoran, produk kosmetik yang mengandung zat antiseptik yang menjaga atau mengurangi kerusakan akibat bakteri sehingga bau badan dapat dikendalikan. Metode yang digunakan adalah metode penelitian kepustakaan, yaitu metode pengumpulan, pembacaan dan pencatatan bahan pustaka, serta pengelolaan bahan penelitian dengan mencari berbagai artikel penelitian di database. Kajian ini bertujuan untuk menganalisis seberapa besar manfaat daun belutinosa Mengurangi intensitas bau badan. Dari hasil pemeriksaan, daun Berunta mengandung protein 17,78-19,02, vitamin C 98,25mg/100g, karoten 2,55g/100g, dan komposisi kimia daun Beruntas mengandung senyawa alkaloid (0,316%). Flavonoid (4,18%), tanin (2,351%), minyak atsiri 4,47%, fenol, asam klorogenat, natrium, kalsium, magnesium dan fosfor dapat digunakan sebagai produk melawan Staphylocus epidermis. Kata Kunci: Daun Beluntas, Deodoran, Penghilang Bau, Bahan Alam
ОСВІТНІ ТРУДНОЩІ ТА РІВНІ ПІДТРИМКИ ДІТЕЙ З ДИСЛАЛІЄЮ В ОСВІТНЬОМУ ПРОЦЕСІ
Authors: Грибань Галина 
Published: June 2023

Статтю присвячено розширеному висвітленню освітніх труднощів та рівнів підтримки дітей з дислалією в освітньому процесі. Актуальність даної теми обумовлена пріоритетністю освітніх завдань забезпечення рівного доступу до якісної освіти дітей з особливими освітніми потребами та надання їм високоспеціалізованих комплексних послуг.
Розкрито поняття терміну «дислалія», його основні форми, види порушень та причини виникнення. Автор розкриває перший та другий рівні підтримки дітей з дислалією, що відповідають особливостям функціонування фонетико-фонематичної сторони мовлення при зазначеній нозології. Перший рівень підтримки містить чотири субрівні та передбачає наявність потреби в створенні незначних прилаштувань освітнього середовища. При цьому в учнів виникають незначні, поодинокі труднощі, з якими можна впоратися зусиллями та ресурсами закладу освіти. Другий рівень підтримки передбачає створення прилаштувань освітнього середовища у формі індивідуальної програми розвитку чи то забезпеченні потреби в допоміжних засобах навчання та додатковій підтримці. На другому рівні вже виникає потреба у здійсненні комплексної психолого-педагогічної оцінки розвитку дитини на базі інклюзивно-ресурсного центру. Підґрунтям для визначення висвітлених особливостей стану сформованості фонетико-фонематичної сторони мовлення та висвітлених освітніх труднощів слугують методичні рекомендації для інклюзивно-ресурсних центрів щодо визначення категорій (типології) освітніх труднощів у осіб з ООП та рівнів підтримки в освітньому процесі.
Охарактеризовані рівні підтримки закладають перспективи для розробки ефективного діагностичного комплексу для їх визначення та становлять основу для планування напрямів оптимальної корекційно-розвивальної роботи. У статті представлено основні напрями методики діагностики фонетичного оформлення мовлення при дислалії. Розкрито зміст, способи та умови проведення діагностичних заходів, спрямованих на дослідження функціонування фонетико-фонематичної сторони мовлення. Практичні рекомендації та розкриття ключових діагностичних напрямів сприятиме реалізації змісту логопедичної допомоги дітям з органічними і функціональними порушеннями діяльності мовленнєвого апарату
Parasite Diversity and Histopathological Changes Due to Infection on Three Croakers (Pennahia Anea, Panna Microdon and Johnius Argentatus) of Saint Martin’s Island, Bay of Bengal
Authors: Sehrina Subrina , Kabir Nasima , Sarkera Anirban , Chowdhury Mehrab , Baki Mohammad Abdul , Ahmed Md Sagir 
Published: June 2023

This study investigated the parasites of three species of croakers (Pennahia anea, Panna microdon, and Johnius argentatus) and their effect on host’s tissues. Fish samples were collected directly from the local fishermen and the fish landing station of Saint Martin’s Island, Bay of Bengal on a regular monthly basis. A total of 448 individuals of parasites were collected of which nine species of parasites were identified including three crustaceans, four nematodes, one pentastomida, and one acanthocephala. The nematode Procamallanus longus had the highest prevalence (50%) and intensity (10.33) compared with the other parasites. The prevalence and intensity of parasites were slightly higher in female fish (55%, 35) than in male fish (50%, 20). The stomach and liver were the most favorable infection sites (53.33%). Furthermore, parasites with the largest length and weight showed the highest prevalence and intensity (66.66% and 38.4 as well as 80% and 72.5, respectively). In histopathological investigations, the most important alterations in various tissues of fish were hemorrhage, necrosis, fatty droplets, edema, vacuolar degenerations, missing villi, haemosiderotic nodules, ovarian follicle disruption, and parasitic cell distribution.
Bioresearch Commu. 9(2): 1297-1304, 2023 (July)
Isolation and Characterization of Chemical Compounds from the Stem Bark Fractions of Citrus Grandis and Evaluation of Their Antimicrobial, Cytotoxic, and Antioxidant Activities
Authors: Sakib Sheikh Adnan , Mahmud Zimam , Karim Md Rejaul , Rahman Tania , Haque Md Enamul 
Published: June 2023

Citrus grandis belongs to the Rutaceae family and is a naturally occurring citrus plant. The fractionated crude extracts of C. grandis have been studied for the investigation of its phytochemicals and allowed for the evaluation of biological activities, especially antimicrobial, cytotoxic, and antioxidant activities. At first, we assessed the antibacterial and antifungal properties using the disc diffusion method and conducted cytotoxicity screening using the brine shrimp lethality bioassay. Among the raw extracts, we isolated two compounds named CG-F3-B1 and CG-F3-B2 through column chromatographic separation of the chloroform extract. By comparing their proton NMR spectra with published spectra, we identified the chemical structures of these compounds as Zeylenol and Limonin, respectively. Regarding antibacterial testing, we observed that the methanol soluble fractions and petroleum ether fractions exhibited mild to moderate activity against bacteria. Additionally, the ethyl acetate soluble fraction showed moderate antibacterial activity. In addition, the crude extract displayed moderate antifungal activity against specific fungi. Furthermore, the cytotoxic assay revealed a relevant cytotoxic effect of a crude extract with an LC50 value of 37 μg/ml. The antioxidant activity was determined using the DPPH assay, and the methanol soluble extract exhibited modest antioxidant activity with an IC50 value of 89 μg/ml. Our findings demonstrated that the stem bark fractions and isolated compounds from C. grandis exhibited various promising biological activities, including antibacterial, antifungal, cytotoxic, and antioxidant properties.
Bioresearch Commu. 9(2): 1320-1329, 2023 (July)
Screening of Anti-inflammatory and Analgesic Activities of Caulerpa Racemosa from the Bay of Bengal, Bangladesh
Authors: Chowdhury Khadiza Rezwana , Alim Md Abdul , Zaman Nazia Rifat , Nayem Abu , Audri Ethneen Mustafa , Mondal Pujan , Hossain Mohammad Nazir 
Published: June 2023

Caulerpa spp; is a remarkably potential seaweed due to its pharmacological importance, high nutritional compositions, biological activities , and human health benefit. It is a species of ulvophyte green algae inhabiting mostly in the intertidal and shallow sub-tidal coastal regions in the Asia- Pacific and commonly consumed in South-East Asia for its high contents of vitamins and minerals. Besides its culinary uses, it is well-reported for its antibacterial, antifungal, diabetes, blood pressure, and lipid-lowering properties. However, to date, no extensive assessment of the diversity, distribution, and biological activity assay of these seaweeds found on the Bangladesh coast has been carried out. This study aimed at anti-inflammatory and analgesic studies of 50% ethanolic extract of Caulerpa racemosa. collected from St. Martin's Island, Bangladesh. Consequently, secondary metabolites such as steroids, flavonoids, glycoside, and saponin were also detected in the phytochemical assay. In the present study, 25 & 50mg/kg body weight of ethanolic extract of C. racemosa was used in hot plate, acetic acid, formic acid, and carrageenan-induced paw edema in Swiss albino mice showing C. racemosa extract has significant analgesic and anti-inflammatory properties.
Bioresearch Commu. 9(2): 1330-1339, 2023 (July)
Ultra-diluted Atropine Belladonna Managed Lipoma: A Study of Two Cases
Authors: Hasan Nazmul 
Published: June 2023

A lipoma is a benign tumor of fatty tissues. It is usually harmless; however, may sometimes need laboratory examinations to confirm diagnosis. Conventional medicines are mostly ineffective in diminishing fat spar, therefore surgical removal is preferred. This article is to report case studies of two individuals of a fairly large lipoma, which were treated with ultra-diluted atropine belladonna. In both cases the lipoma wall punctured within few days, drained all the debris and healed lesion surface observed within four weeks. This alternative treatment evidenced that ultra-diluted atropine belladonna may have significant role in lipoma management. More extensive research is needed to understand the mode of action of ultra-diluted atropine belladonna in managing lipomas.
Bioresearch Commu. 9(2): 1357-1360, 2023 (July)
Acute Kidney Injury Following Paediatric Cardiac Surgery: Experience of A Paediatric Cardiac Center of Bangladesh
Authors: Hossain Mohammad Makbul , Ahamed Sabarin , Tarik Khalifa Mahmud , Al Amin Dewan Md 
Published: June 2023

Background: Acute kidney injury following cardiac surgery in children is a relatively common phenomenon. The risk ranges from 15% to 64% with a mortality rate of 10% to 89% for those who need dialysis.
Objective: To identify the occurrence of acute kidney injury following cardiac surgery in children, as well as its consequences and treatment options.
Methods: This study was conducted in the pediatric cardiac recovery center at Bangladesh Shishu Hospital & Institute from January 2019 to December 2020. Using the KDIGO (kidney disease improving global outcome) criteria, 50 children having cardiac surgery were assessed for the occurrence of AKI. Children were divided into two groups. The AKI group consists of 20 patients, whereas the non-AKI group consists of 30 patients. Age, sex, cardiac illness, past operations, RACHS-1 (Risk adjustment for congenital Heart surgery) and pre and post-operative creatinine levels were noted. Fisher’s exact test was used to determine whether or not AKI was associated with categorical factors, while the Mann- Whitney U-test was used to see whether or not AKI was associated with continuous variables.
Results: Mean age of study population was 4.50±4.03 years for those who did not develop AKI and 7.55±5.79 years for those who did. Male constituted a majority in both groups. Despite the fact that patients with AKI were more acidotic at baseline, lower bicarbonate levels were not linked to an increased risk of AKI (p=0.89). Neither group had higher or lower pressure than the other. Time spent in bypass and crossclamping was comparable across AKI and non-AKI patients. Patients with AKI did not have a higher risk of developing extracellular fluid excess than non-AKI patients. There was no significant difference between the groups in terms of the average time spent on mechanical ventilation or total hospital stay in days (p=0.17 and p=0.62, respectively). Duration of stay in the cardiac recovery increased for patients who had AKI (p=0.02). The mortality rate among the AKI patients was 20% (4/14). In the control group without AKI, there was one death (3.33%) (p 0.0001).
Conclusion: AKI is common complication of paediatric cardiac surgery. Prolong times spent on mechanical ventilation in the ICU and in the hospital have all been linked to AKI.
DS (Child) H J 2021; 38(1): 44-48
Infantile Inflammatory Bowel Disease in A 14 Month Old Bangladeshi Boy: An Unusual Presentation
Authors: Farhana Tanzila , Mahmud Salahuddin , Parvez Mashud , Baidya Madhabi , Hasan Ahmed Rashidul , Ahmed Syed Shafi 
Published: June 2023

Abstract not available
DS (Child) H J 2021; 38(1): 56-60
Left Hindquarter Amputation due to High-Grade Pleomorphic Sarcoma of the Groin: A Case Report
Authors: Hafiz M. Zaki Abdul , Brahma Bayu , Sofyan Rian Fabian 
Published: June 2023

Introduction:Hindquarter amputation or known as hemipelvectomy is a surgical technique that is primarily used for the eradication of malignant primary soft tissue and bone tumors of the pelvis, hip, and upper thigh regions. Occasionally, hindquarter amputation has been employed in the treatment of severe trauma, metastases, and infection. This case report aims to give a lesson in the case of the High-Grade Pleomorphic Sarcoma of the Groin because this is a very rare case and most patients are not willing to undergo amputation.Case Presentation: A 54-year-old male patient came with a complaint of a lump in the thigh. Initially, the lump was as big as a marble and has been getting bigger since last year. The size of the lump was approximately 30 x 30 x 30 cmConclusions: The most common indications for amputation in patients with the primary localized disease were extensive involvement of the limb-girdle, multiple muscle compartment involvement, multifocality, and unsuitability for limb-sparing surgery, typically due to lack of a salvage option. Hindquarter amputation was used as a treatment for 13% of all pelvic bone sarcomas where there is a realistic chance of control of symptoms or long-term survival.comas.
The Pattern of Prostate Cancer Screening and Diagnosis among Indonesian Urologists: A Questionnaire Survey
Authors: Firman Muhammad , Rahman Fakhri , Hamid Agus Rizal Ardy Hariandy , Mochtar Chaidir Arif 
Published: June 2023

Background: Prostate cancer (PCa) screening and diagnosis are mandatory to deliver optimal management in the early phase. Even though it has been discussed in many guidelines, the implementation of PCa screening and diagnosis in Indonesia remains unknown. This study aims to evaluate the pattern of PCa screening and diagnosis among Indonesian urologists and their adherence to guidelines. Methods: This cross-sectional study was conducted between February and July 2019. Respondents were Indonesian urologists registered as members of the Indonesian Urological Association (IUA) and had already practiced for at least six months. Data were collected using questionnaires, which were distributed at a national urology symposium and electronically via Google Form. Data were presented descriptively, and all data were processed using SPSS version 23. Results: Of 458 urologists, 195 (42.6%) gave full responses. Most of the respondents, 181 (92.8%) urologists, used the IUA guidelines. Among the 103 (52.8%) respondents who performed screening, nearly half (42.7%) agreed to screen patients aged ≥ 50 years or ≥ 45 years with a family history of PCa. Moreover, 76.8% would repeat screening annually, and 35.6% would stop when the patient’s age reached 70 years old. Digital rectal examination (DRE) was frequently performed for screening (74.5%), while prostate-specific antigen (PSA) tests were only performed in 52.3% of cases. The PSA test was available in 74.8% of hospitals. Transurethral resection of the prostate (TURP) was still used by 67.2% of respondents for diagnosis. Only 52.3 % of participants used transrectal prostate biopsy for diagnosis, using anesthesia (78.1%) during the procedure, and increased PSA level (98%) as its indication. However, Transrectal Ultrasound (TRUS) was only available in 49% of hospitals. This study found that Indonesian urologist adherence level toward guidelines was 63.3% (9–100%). Conclusions: PCa screening and diagnosis are still varied among Indonesian urologists, which might arise due to the different availability of diagnostic modalities.
Análise da variação no número dos casos de melanoma maligno e de outras neoplasias malignas da pele em todas as regiões do Brasil no período de 2015 até 2022
Authors: Luz Renata Garcez da , Nobre Leandra Ferreira Marques , Corrêa Amanda Sarmento , Ferrandin Rafaela Röhl , Matos Silvia Regina Seibel de , Moscal Aline Pedroso 
Published: June 2023

O câncer pode ser definido por um conjunto de mutações imprevisíveis sofridas por células do organismo. Três tipos de neoplasias malignas são as principais responsáveis pelo número alarmante de casos de câncer de pele. As formas mais comuns e com maior taxa de cura são os Carcinoma Espinocelular e Carcinoma Basocelular, já o tipo mais agressivo e com altas taxas de disseminação metastática é denominado melanoma. O objetivo dessa pesquisa é uma análise epidemiológica dos anos de 2015 até 2022, sobre o melanoma maligno cutâneo e outras neoplasias malignas da pele em todas as regiões do Brasil. O estudo é descritivo e quantitativo, com dados coletados da plataforma online DATASUS. Os resultados demonstraram que o Sul é a região com mais casos de melanoma e de outras neoplasias malignas da pele a cada 100 mil habitantes. Outro resultado de destaque, é o alto número de diagnósticos de câncer de pele no período da pandemia, tendo uma redução de apenas 24,42% no ano do ápice da pandemia, mas os casos diagnosticados no período pandêmico ainda são maiores que a soma de todos os diagnósticos nos anos de 2015 até 2018. Sendo assim, conclui-se que o grande número de casos diagnosticados de câncer de pele se deve a campanhas de conscientização, acesso ao especialista e implementação de um banco de dados online e efetivo. No entanto, os diagnósticos de melanoma no estadiamento 4 são alarmantes e necessitam de medidas que promovam um diagnóstico em fases precoces da doença.
Analisis Pelaksanaan Program Penanggulangan TB Paru pada Masa Pandemi Covid-19 di Puskesmas Medaeng Sidoarjo
Authors: Nofianti Mey Lia 
Published: June 2023

Pelaksanaan penanggulangan TB Paru pada masa pandemi Covid-19 dilakukan dengan menyiapkan tenaga kesehatan yang telah diberi pelatihan khusus untuk pengobatan TB Paru, menyediakan fasilitas untuk implementasi dan menyediakan alat untuk skrining dan tidak lanjut pasien, pelaksanaan program ini dilakukan di ruang terbuka dengan memisahkan antara pasien TB dan pasien bukan TB. Penelitian ini bertujuan untuk menganalisis pelaksanaan program penanggulangan TB Paru pada masa pandemi Covid-19 di Puskesmas Medaeng Sidoarjo. Penelitian ini merupakan penelitian kualitatif dengan jumlah partisipan 4 orang pemilihan partisipan dilakukan menggunakan purposive sampling. Analisis data penelitian ini menggunakan model mils and huberman. Teknik pengumpulan data dalam penelitian ini adalah dengan observasi, wawancara, FGD, dokumentasi dan telaah dokumen. Keabsahan dan validitas data penelitian ini menggunakan teknik triangulasi sumber data. Hasil penelitian ini menunjukkan bahwa pelaksanaan program penanggulangan TB Paru pada masa pandemi Covid-19 di Puskesmas Medaeng berdasarkan Sistem Input masih belum dilakukan dengan baik. Sistem proses masih belum berjalan dengan optimal dan Otuput masih terdapat beberapa kendala yang menyebabkan pelaksanaan program TB Paru tidak berjalan dengan optimal akibatnya capaian penemuan kasus dan kesembuhan kurang dari target yang telah ditentukan. Simpulan pada penelitian ini adalah pelaksanaan program penanggulangan TB Paru pada masa pandemi Covid-19 di Puskesmas Medaeng Sidoarjo belum terlaksana dengan optimal. Diharapkan bagi kepala puskesmas dan penanggung jawab TB Paru hendaknya melakukan evaluasi dan tindak lanjut terkait kendala yang membuat pelaksanaan program TB Paru tidak berjalan dengan optimal.