bluuebunny/crossref_metadata_2025_split huggingface dataset:
Periodontal treatment and subsequent clinical outcomes and medical care costs: A retrospective cohort study
Authors: Michalowicz Bryan S. , Anderson Jeffrey P. , Kottke Thomas E. , Dehmer Steven P. , Worley Donald C. , Kane Sheryl , Basile Sarah , Rindal D. Brad 
Published: August 2023

Introduction
Periodontitis is a common oral disease associated with coronary artery disease (CAD), cerebrovascular disease (CBVD) and type 2 diabetes (T2D). We studied if periodontitis treatment improves clinical outcomes and reduces medical care costs in patients with CAD, CBVD or T2D.

Methods
We used clinic records and claims data from a health care system to identify patients with periodontitis and CAD, CBVD or T2D, and to assess periodontal treatments, hospitalizations, medical costs (total, inpatient, outpatient, pharmacy), glycated hemoglobin, cardiovascular events, and death following concurrent disease diagnoses. We compared clinical outcomes according to receipt of periodontal treatment and/or maintenance care in the follow-up period, and care costs according to treatment status within one year following concurrent disease diagnoses, while adjusting for covariates. The data were analyzed in 2019–21.

Results
We identified 9,503 individuals, 4,057 of whom were in the CAD cohort; 3,247 in the CBVD cohort; and 4,879 in the T2D cohort. Patients who were selected and elected to receive treatment and maintenance care were less likely to be hospitalized than untreated individuals (CAD: OR = 0.71 (95% CI: 0.55, 0.92); CBVD: OR = 0.73 (0.56, 0.94); T2D: OR = 0.80 (0.64, 0.99)). Selection to treatment and/or maintenance care was not significantly associated with cardiovascular events, mortality, or glycated hemoglobin change. Total care costs did not differ significantly between treated and untreated groups over 4 years. Treated patients experienced lower inpatient costs but higher pharmacy costs.

Conclusions
Patients with periodontitis and CAD, CBVD or T2D who were selected and elected to undergo periodontal treatment or maintenance care had lower rates of hospitalizations, but did not differ significantly from untreated individuals in terms of clinical outcomes or total medical care costs.
Autonomic responses to aerobic and resistance exercise in patients with chronic musculoskeletal pain: A systematic review
Authors: Uzawa Hironobu , Akiyama Kazuya , Furuyama Hiroto , Takeuchi Shinta , Nishida Yusuke 
Published: August 2023

BackgroundIt is unknown whether patients with chronic musculoskeletal pain (CMP) show autonomic dysregulation after exercise, and the interventional effects of exercise on the autonomic dysregulation have not been elucidated. The objectives of this study were to reveal acute autonomic responses after aerobic and resistance exercises and the interventional effects of both exercises on autonomic dysregulation in patients with CMP.MethodsA systematic search using nine electronic databases was performed based on three key search terms: “chronic musculoskeletal pain,” “autonomic nervous system,” and “exercise.” Data were extracted from measurements of the autonomic nervous system and pain.ResultsWe found a total of 1170 articles; 17 were finally included, incorporating 12 observational and five interventional studies. Although a comparator has not been specified, healthy controls were compared to patients with CMP in observational studies. Three of five interventional studies were pre-post study with healthy controls as a comparator or no controls. The other two interventional studies were randomized controlled trial with a different treatment e.g., stretching. There were four good, 10 fair, and three poor-quality articles. The total number of participants was 617, of which 551 were female. There was high heterogeneity among the five disease conditions and nine outcome measures. Following one-time exposure to aerobic and resistance exercises, abnormal autonomic responses (sympathetic activation and parasympathetic withdrawal), which were absent in healthy controls, were observed in patients with CMP. The effects of aerobic and resistance exercise as long-term interventions were unclear since we identified both positive effects and no change in the autonomic activities in patients with CMP.ConclusionsThis study indicates dysfunctional autonomic responses following one-time exposure to exercise and inconsistent interventional effects in the autonomic activities in patients with CMP. Appropriate therapeutic dose is necessary for studying the management of autonomic regulation and pain after exercise.
Inclusive Screenwriting for Film and Television, Jess King (2022)
Authors: de Estrellas Madison río 
Published: August 2023

Review of: Inclusive Screenwriting for Film and Television, Jess King (2022)
Abingdon: Routledge, 268 pp.,
ISBN 978-0-36777-218-5, p/bk, $34.36
ISBN 978-0-36777-220-8, h/bk, $136.00
ISBN 978-1-00317-031-0, e-book, $34.36
Gastrointestinal sensory neuropathy and dysmotility in Fabry disease: Presentations and effect on patient's quality of life
Authors: Bar Nir , Karaa Amel , Kiser Katheryn , Zar-Kessler Claire , Kuo Braden 
Published: August 2023

Abstract

Introduction:
Fabry disease is a rare multisystemic lysosomal disease resulting in variable manifestations of the gastrointestinal (GI), neurologic, cardiac, and renal systems. Whether GI manifestations are a result of gut dysmotility is undetermined. We aimed to explore GI manifestations in depth, their effect on patients with Fabry disease, and to characterize gut motility.

Methods:
We recruited adult patients with Fabry disease reporting GI manifestations. All patients answered a battery of questionnaires covering symptom severity, GI specific quality of life (QoL), and work/productivity questionnaires, and underwent a wireless motility capsule (WMC) to measure pan-gut motility.

Results:
In 48 patients with Fabry disease, abnormal bowel habits and abdominal pain were the most common symptoms. Bloating, nausea, vomiting, and reflux were also prevalent. Neurologic manifestations were found in 95.8% of patients and along with their GI manifestations. Dysmotility was found in less than 35% of WMC tests. Colon transit time was associated with constipation severity and Bristol stool scale. Several GI symptoms were associated with reduced QoL, anxiety and work/productivity, but not Fabry severity score.

Discussion:
This is the largest study of GI manifestations in patients with Fabry disease that characterizes gut motility. We found little association between GI manifestations and motility indices, suggesting that visceral-hypersensitivity may be a major driver of symptoms. GI symptoms affect different aspects of patients’ lives, yet are not always well discussed or optimally managed in Fabry disease. Disease severity scores, when used for therapeutic decision making do not often include GI symptoms or their impact.
The footbridge Jesípek – application of radar interferometry for dynamic response evaluation
Authors: Čáp Miroslav , Polák Michal , Plachý Tomáš , Talich Milan , Havrlant Jan , Soukup Lubomír , Antoš Filip 
Published: August 2023

Recent advances in radar systems have led to the development of radar interferometry (RI) methods for contactless vibration monitoring of large-scale structures, i.e. bridges, water tower reservoirs, and factory chimneys. Interferometric radars are devices capable to measure with 200 Hz sampling frequency and relative movement precision of 0.1 mm up to 0.01 mm. The major part of this paper describes an in-situ footbridge experiment near Hradec Králové. Radar interferometry devices were deployed along with ordinary techniques compounded by accelerometers, wiring, and acquisition station. Experiment was focused on the evaluation of basic dynamic structural properties such as natural frequencies and mode shapes. A lot of attention was also given to the result comparison of these measurement methods. Test results have confirmed the applicability of RI for bridge vibration monitoring.
Sex-Based Differences in the Presentation and Outcomes of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis
Authors: Zhang Yu , Qiu Yu , Luo Jinming , Zhang Jian , Yan Qingqing 
Published: August 2023

Abstract

Background
The study aimed to review differences in the presentation and outcomes of acute pulmonary embolism (PE) between men and women.

Methods
PubMed, CENTRAL, Web of Science, and Embase were searched for studies comparing clinical features or outcomes of PE between men and women. Baseline comorbidities, risk factors, clinical features, and mortality rates were also compared between men and women.

Results
Fourteen studies were included. It was noted that men presented with PE at a statistically significantly younger age than women (P < .001). Smoking history (P < .001), lung disease (P = .004), malignancy (P = .02), and unprovoked PE (P = .004) were significantly more frequent among men than among women. There was no difference between the sexes for hypertension, diabetes, and a history of recent immobilization. A significantly higher proportion of men presented with chest pain (P = .02) and hemoptysis (P < .001), whereas syncope (P = .005) was more frequent in women. Compared with men, women had a higher proportion of high-risk PE (P = .003). There was no difference in the use of thrombolytic therapy or inferior vena cava filter. Neither crude nor adjusted mortality rates were significantly different between men and women.

Conclusion
This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and women. Limited data also suggest that women more frequently had high-risk PE compared with men, but the use of thrombolytic therapy did not differ between the 2 sexes. Importantly, both crude and adjusted data show that the mortality rate did not differ between men and women.
Planungskonflikte und Gerechtigkeit: Konzeptionelle Überlegungen am Beispiel des Ausbaus der Windenergie im Nordosten Deutschlands
Authors: Eichenauer Eva 
Published: August 2023

The energy transition and the expansion of renewable energies are central challenges to planning. In view of tightened climate protection targets and the associated rise in installation capacity, planning conflicts are likely to intensify further in the coming years. At the same time, democratic institutions are under increasing pressure. The expansion of wind energy must proceed swiftly while democratic participation must be ensured. Based on planning conflicts over wind turbines in Mecklenburg-West Pomerania and Brandenburg, this paper addresses the extent to which research on planning conflicts can benefit from a justice perspective, both in theoretical-conceptual and empirical terms. Drawing on concepts from research on spatial justice, energy justice, and planning justice, the paper uses a three-dimensional conception of justice to identify access points for dealing constructively with conflicts. First, conflicts have to be recognized as such and their productive potential has to be acknowledged. Second, strategies have to be established that allow conflicts to be dealt with constructively. In doing so, several dimensions of justice must be taken into account: distributive justice and the question of what is to be distributed according to which criteria, recognition justice and the reflexion on difference and needs beyond hegemonic majority opinion, and finally procedural justice, which is intended to ensure that recognition and fair distribution can be implemented. In this way, a proactive attitude towards planning conflicts can make a central contribution to sustainable and democratic planning.
Reconciling Science and Foreign Relations in The Hague
Authors: Somsen Geert 
Published: August 2023

Abstract
From 18 to 25 August, IUPAC will convene in The Hague. This is not the first time. One of the earliest IUPAC conferences, in 1928, also took place in the Dutch city. This was a truly historic meeting, because it was there that decisive steps were taken toward the reintegration of German, Austrian, and Hungarian chemists who had been banned from international science since the First World War, as has earlier been described by Jorrit Smit and Danielle Fauque in this magazine. An informal gathering the following year, in The Hague’s beach resort Scheveningen, finalized the process [1]. The rifts of war had been repaired; internationalism revived.
From Competition Law to Platform Regulation – Regulatory Choices for the Digital Markets Act
Authors: Podszun Rupprecht 
Published: August 2023

Abstract
The digital landscape is characterized by the concentration of power in the hands of a few “gatekeepers.” Europe’s legal answer, the Digital Markets Act (DMA), constitutes a new legal approach. It aims at restricting this power and ensuring “fairness and contestability.” Traditionally, the tools of competition law were used to set the basic rules of how to operate in markets. The shift to a different technique, regulatory law, prompts three questions: First, why is it necessary to deviate from the path set in competition law? Second, what are the differences between the competition law approach and the regulatory approach of the DMA? Third, what are key decisions to be taken within the new regulatory framework? At the outset, the DMA is presented.
A landslide susceptibility assessment method based on auto-encoder improved deep belief network
Authors: Zhang Lifeng , Pu Hongyu , Yan Haowen , He Yi , Yao Sheng , Zhang Yali , Ran Ling , Chen Yi 
Published: August 2023

Abstract
The landslide susceptibility assessment is an essential part of landslide disaster risk identification and prevention. However, the binarization of the hidden layer limits the parameterization ability of the conditional probability of visible layer, making the training process of restricted Boltzmann machine more difficult and further limiting the accuracy and efficiency of deep belief network (DBN) model in landslide susceptibility assessment. Therefore, this study proposed a landslide susceptibility assessment method based on Auto-Encoder (AE)-modified DBN. Zhouqu County, Gansu Province in the People’s Republic of China, was selected as the study area. Historical landslides in Zhouqu County were identified using small baseline subset interferometric synthetic aperture radar technology and optical image. Landslide factors were screened based on a geographical detector and stepwise regression method. The Logcosh loss function and determinant coefficient R
2 index were used to evaluate the training process of the AE model, and the balanced cross entropy loss function was used to evaluate the entire network training process. In addition, the area under the curve (AUC) of the synthetical index model (SIM), support vector machine (SVM), and multilayer perceptron (MLP) were compared and evaluated. The results indicated that the proposed model could significantly improve the accuracy of landslide susceptibility assessment. The AUC value of the proposed model was 0.31, 0.12, and 0.11 higher than that of SIM, SVM, and MLP, respectively. Therefore, the improved DBN model based on AE proposed is reliable for early landslide identification and prediction.
Corona and the Cross: Religious Affiliation, Church Bans, and Covid Infections
Authors: Strulik Holger , Yakubenko Slava 
Published: August 2023

Abstract
We examine the effectiveness of church service bans in containing the spread of Covid-19 in Germany. We furthermore investigate how differences in the local religious affiliations affect infections and the effectiveness of church bans and other church-related restrictions. We find that, without a ban, infections per capita are higher in districts (Landkreise) with larger shares of religious population. In panel analysis, controlling for district fixed effects and a host of potential confounders, we find that church bans effectively reduce infections. For a ban in place for 14 days before a considered day, the predicted growth factor of infections is lower by 0.9 of its standard deviation. Finally, we show that Easter contributed significantly to the growth of infections in 2020 and 2021. The growth factor of infections was lower in regions with larger shares of Catholics and Protestants during Easter 2020 (when a church ban was in place) but not in 2021 (without a ban).
Sub-disciplinary variation of metadiscursive verb patterns in English research articles: a functional analysis of medical discourse
Authors: Chen Songyun , Xu Jiajin , Feng Xin 
Published: August 2023

Abstract
As a cover term for the negotiation of propositional information and reader engagement, metadiscourse has gained considerable attention from scholars of academic discourse. Recent studies have extended to previously unexplored structures that realize metadiscourse, such as ‘metadiscursive nouns’ (Jiang and Hyland 2018. Nouns and academic interactions: A neglected feature of metadiscourse. Applied Linguistics 39. 508–531). Among various linguistic resources, verbs are often regarded as a linguistic element undertaking multiple discourse acts and functions in different contexts, with some acts and functions being metadiscursive. Based on previous studies on reporting verbs and functional sentence stems, this study proposes the concept of metadiscursive verb patterns (MVPs) and examines this linguistic resource in a self-built MedDEAP corpus of five million words, a clinical medicine English research article corpus consisting of 18 sub-disciplines. We conducted an intradisciplinary investigation into MVPs to analyze their structural and functional variations across the sub-disciplines of medical academic English. The findings revealed that most MVPs exhibit a preference for some sub-disciplines, and a few sub-disciplines reflect certain characteristic genre features in the use of certain MVPs. It is shown that medical academic discourse is characterized by methodological and conceptual cross-fertilization. Hence, variation in MVPs is a natural linguistic representation of interdisciplinary synergy. Based on our findings, we conclude by addressing the pedagogical implications for proper use of MVPs in academic writing.
Glucose levels are not the same for everyone: a real-world big data study evaluating fasting serum glucose levels by sex and age among children
Authors: Avnon Ziv Carmit , Banon Tamar , Ben Tov Amir , Chodick Gabriel , Gabay Linoy , Auerbach Adi , Hirsch Harry J. , Levy Khademi Floris 
Published: August 2023

Abstract

Objectives
Understanding the normal range of laboratory values as pertained to different age groups and males or females is paramount in health care delivery. We aimed to assess the distribution of morning fasting serum glucose levels by age and sex in the general population of children using a large-scale population-based cohort.

Methods
A retrospective study with real-world de-identified data from a large, state mandated health fund in Israel among children aged 2–18 years old between 2006 and 2019. Age, sex, and BMI differences in mean glucose levels were evaluated.

Results
Study included 130,170 venous blood samples from 117,411 children, 53.3 % were female. After adjusting for age boys had higher fasting serum glucose levels than girls, with a mean of 89.21 ± 8.66 mg/dL vs. 87.59 ± 8.35 (p<0.001) [4.95 ± 0.48 mmol/L vs. 4.86 ± 0.46]. Compared to the 15 to 18 year-olds (88.49 ± 7.63 mg/dL) [4.92 ± 0.42 mmol/L], 2 to 5 year-olds had lower glucose levels (84.19 ± 10.65, [4.68 ± 0.59] (p<0.001)), 11 to 14 year-olds had higher glucose (90.40 ± 7.42 [5.02 ± 0.41], (p<0.001)) and 6 to 10 year-olds showed no difference (88.45 ± 8.25) [4.91 ± 0.46]. 33.0 % (n=42,991) had a BMI percentile record the same year as their glucose test result. There was a weak yet significant positive association between blood glucose levels and BMI.

Conclusions
Our large cohort indicates that boys have slightly higher fasting serum glucose levels than girls, as do adolescents compared to younger children. This finding is important for the delivery of adequate health care, screening for illness and avoiding unnecessary investigations and tests.
Modular Direct Laser Writing setup for high precision nanostructuring
Authors: Häcker Annika-Verena , Stauffenberg Jaqueline , Leineweber Johannes , Ortlepp Ingo , Hoffmann Maximilian , Manske Eberhard 
Published: August 2023

AbstractThe increasing demand for micro- and nanofabrication and in parallel the increasing requirements on feature size and resolution is leading to an enormous growth in the field of multi-photon three-dimensional fabrication. To enable new and diverse investigations in this field and to enable high precision for nanofabrication on large areas, a high precision positioning system is combined with an ultra-short pulse laser system. The aim is a modular setup with constant adherence to the Abbe-comparator principle in order to achieve systematic improvements in the area of Direct Laser Writing. For a high-quality identification of the microstructures a measurement tool based on atomic force microscopy is used. To enable the fabrication of continuous micro- and nanostructures on large area, an extremely high positioning precision is used, where no further stitching methods are necessary. Therefore as base of the Direct Laser Writing system the nanopositioning and nanomeasuring machine (NMM-1) is used, which was developed at Technische Universität Ilmenau together with SIOS Meßtechnik GmbH, with a positioning volume of 25 mm × 25 mm × 5 mm and a positioning resolution in the sub-nanometer range. First investigations already confirmed that microfabrication with a Femtosecond Laser and the NMM-1 could be realized and showed the possibility of further developments in the field of Direct Laser Writing. Now the modular structure as a research platform is designed in such a way that the various extensions and measurement setups for large-scale investigations can always be implemented in a metrologically traceable manner. The presented work shows the development of a modular functional setup of an exposure system and NMM-1, which enables micro- and nanofabrication and an improvement in the structure size over large areas.
Laststeuerungsprogramme am Beispiel der Maschinenbelegungsplanung
Authors: Füchtenhans Marc , Glock Christoph H. 
Published: August 2023

AbstractAngesichts des hohen Energiebedarfs in der verarbeitenden Industrie und der Notwendigkeit, erneuerbare Energiequellen trotz ihrer natürlichen Schwankungen weiter auszubauen, wird es immer wichtiger, Energienachfrage und Energieverfügbarkeit aufeinander abzustimmen. Mithilfe von Laststeuerungsprogrammen können Netzbetreiber Anreize für Verbraucher schaffen, den Energiebedarf in kritischen Situationen so anzupassen, dass die Netzstabilität nicht gefährdet wird. Auf der Verbraucherseite können mathematische Planungsmodelle genutzt werden, um Potenziale zur Flexibilisierung des Energieverbrauchs zu identifizieren und nachhaltige Produktionsprozesse zu schaffen. Dabei zeigt eine durchgeführte Studie, dass Laststeuerungsprogramme durchaus wirksam eingesetzt werden können, jedoch mit Auswirkungen auf die wirtschaftliche Performance von Produktionsprozessen.
Kornfeinung mittels Flachbackenwalzen
Authors: Peter Roe Christopher , Viertel Lars , Kriwall Mareile , Hedicke-Claus Yorck , Stonis Malte , Behrens Bernd-Arno 
Published: August 2023

Abstract
Durch die Erzeugung ultrafeinkörniger Gefüge können die Materialeigenschaften eines Werkstoffs verbessert werden. Ultrafeinkörniges Gefüge besitzt eine hohe Festigkeit bei gleichzeitig hoher Duktilität. In dieser Arbeit wird beschrieben, wie mithilfe eines Walzprozesses Einfluss auf das Gefüge eines Werkstoffs genommen werden soll. Der Prozess wird simulativ untersucht und Prozessfenster mithilfe der statistischen Versuchsplanung für die praktische Erprobung bestimmt.