bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review of: Brink G., van den. «I proizvela zemlya…» Khristianskaya vera i evolyutsiya. [«And the Earth Produced...» Christian Faith and Evolution] / trans. from the Netherlands and English. Moscow: Biblical and Theological Institute of St. Apostle Andrew
Authors: Кирьянов Д. 
Published: March 2023

Вопросы взаимоотношения христианской веры и эволюционной теории являются одними из наиболее острых и дискуссионных, вызывающих множество споров как среди прихожан, так и среди профессиональных богословов. Сегодня среди христиан широко распространено мнение о том, что необходимо придерживаться строго буквального понимания текстов Священного Писания, отвергнуть современную эволюционную биологию, как пропитанную идеологией натурализма и атеизма, и разработать собственную христианскую науку о сотворении, построенную на правильных библейских (в протестантской среде) или святоотеческих (в православной среде) принципах. С другой стороны, несовместимость религиозной веры и эволюционной биологии стремятся подчёркивать такие представители «нового атеизма», как Р. Докинз, Д. Деннетт и др. Трудность согласования христианского учения и современной эволюционной биологии была наглядно продемонстрирована во множестве современных публичных дискуссий, в частности, в популярной телепрограмме «Не верю» (телеканал «Спас»).
The relationship between Christian faith and evolutionary theory is one of the most acute and debatable issues, causing many disputes among both churchgoers and professional theologians. Today there is a widespread belief among Christians that a strictly literal understanding of the texts of Holy Scripture must be adhered to, rejecting modern evolutionary biology as imbued with the ideology of naturalism and atheism, and developing our own Christian science of creation, built on correct biblical (in the Protestant environment) or sacred-theological (in the Orthodox environment) principles. On the other hand, the incompatibility of religious faith and evolutionary biology is emphasized by such representatives of the "new atheism" as R. Dawkins, D. Dennett and others. The difficulty of reconciling Christian doctrine and modern evolutionary biology has been clearly demonstrated in many contemporary public discussions, in particular in the popular television program "I Do Not Believe" (TV channel "Spas").
The Association Between Fibromyalgia, Hypermobility and Neurodivergence Extends to Families: Brief Report
Authors: Kelly Clive 
Published: March 2023

OBJECTIVES

Fibromyalgia is associated with symptomatic hypermobility. People with these conditions have a higher prevalence of neurodivergent conditions. Many fibromyalgia patients with hypermobility also report similar symptoms within their family. This study explores the presence of diagnosed disorders among close relatives of patients presenting with fibromyalgia and hypermobile Ehlers-Danlos syndrome (hEDS).

METHODS

All patients presenting with both fibromyalgia and hEDS to the rheumatology clinic were invited to participate. Each of these participants reported all confirmed diagnoses of any of neurodivergence, fibromyalgia or hypermobility among their first- and second-degree relatives. Participants were invited to prepare a family tree detailing these diagnoses. We calculated the incidence of each of neurodivergence, fibromyalgia and hypermobility within these relatives and compared them to the incidence derived from families of case-control patients with osteoarthritis.

RESULTS

Among 13 index patients (all female, median age 38 years), 9 had a diagnosed neurodivergent condition (69%). Among their 163 relatives, 68 (42%) had a diagnosed neurodivergent condition, compared to 4.7% among case-control relatives (p>0.00001). The incidence of diagnosed hypermobility and fibromyalgia in relatives of index cases was 36% and 22%, compared to 8% and 4% in case-control relatives (p=0.00001, p=0.00012)

CONCLUSION

This self-reported small case-control study confirms the association of fibromyalgia, hypermobility and neurodivergence, and suggests that close relatives also exhibit this association. Females are disproportionately overrepresented within pain populations, in contrast to neurodivergence in other settings where males predominate, perhaps due to underdiagnosis in females. Gene clustering may contribute to these associations which extend into the community.
Korelasi Gaya Kepemimpinan Dan Lingkungan Kerja Dengan Budaya Kerja Pegawai Madarasah di Sorong Papua Barat
Authors: Yudiawan Agus 
Published: March 2023

Penelitian bertujuan untuk mengetahui dan membuktikan hubungan gaya kepemimpinan dan lingkungan kerja dengan budaya kerja pegawai madarasah di MTs. Sains Al Gebra Kota Sorong. Penelitian ini menggunakan pendekatan kuantitatif dengan populasi sebanyak 25 orang. Teknik pengambilan sampel menggunakan sampel sensus dengan seluruh anggota populasi dijadikan sampel. Data dikumpulkan dengan penyebaran kuesioner dengan skala Linkert berskala 5 (Lima) dan selanjutnya dianalisis menggunakan korelasi product moment dengan taraf kepercayaan 95%. Hasil penelitian menunjukkan bahwa gaya kepemimpinan dan lingkungan kerja memiliki hubungan yang signifikan dengan budaya kerja pegawai di MTs. Sains Al- Gebra Kota Sorong. Koefisien korelasi gaya kepemimpinan dengan budaya kerja sebesar 0,626 berarti memiliki hubungan kuat. Selanjutnya koefisien korelasi 0,569 antara lingkungan kerja dengan budaya kerja dengan korelasi sedang. Kesimpulan yang diperoleh adalah gaya kepemimpinan dan lingkungan kerja dapat memunculkan budaya kerja pegawai, oleh karenanya perlu dioptimalkan.
HUBUNGAN ANTARA HUKUM ISLAM DENGAN HUKUM PUBLIK
Authors: Samin Samin 
Published: March 2023

Hukum Islam berkembang sejalan dengan perkembangan perluasan wilayah Islam serta hubungannya dengan budaya dan masyarakatnya.Al-Qur’an memberikan ketentuan kepada setiap orang Islam untuk menta’ati Allah dan Rasul-Nya.Orang Islam tidak dibenarkan mengambil pilihan lain kalau ternyata Allah Swt dan Rasul-Nya telah menetapkan hukum yang pasti dan jelas.Berlakunya hukum Islam sebagai hukum positif bagi umat Islam indonesia yang merupakan jumlah mayoritas di Negara ini,dilandasi oleh nilai-nilai filosofis,yuridis,dan sosiologis bangsa indonesia. Oleh kartena itu negara berkewajiban untuk menjadikan hukum Islam sebagai hukum positif bagi umat Islam indonesia karena pada dasarnya cara berpikir,pandangan hidup dan karakter suatu bangsa tercermin dalam kebudayaan dan hukumnya.
Automedicação entre profissionais da saúde durante a pandemia da COVID-19
Authors: Luca Marília Mendes de , Venturi Maria Theresa Iorio , Carvalho Beatriz Cortez de , Vitorino Luciano Magalhães , Cortez Paulo José Oliveira 
Published: March 2023

Introdução: Estudos têm demonstrado que a automedicação é uma prática comum no Brasil entre os profissionais da saúde devido à uma tendência em evitar a procura por especialistas. No entanto, poucos estudos avaliaram a automedicação entre esses profissionais durante a pandemia da COVID-19 no Brasil. Objetivo: Analisar a automedicação entre profissionais da saúde durante a pandemia da COVID-19 no Brasil. Métodos: Realizou-se um estudo observacional, transversal com 290 profissionais da área de saúde, que relataram automedicação. Os participantes responderam a um questionário autoaplicável enviado a profissionais de saúde por canais de comunicação online no período entre outubro de 2020 e janeiro de 2021. Resultados: A amostra de 290 profissionais da saúde relataram automedicação durante esse período. Dentre os medicamentos, os mais utilizados, 161, foram analgésicos e anti-inflamatórios, sendo que o motivo de destaque que levou a essa prática é a experiência anterior sobre o sinal/sintoma, majoritariamente cefaleia e enxaqueca, 131 (45,2%). Conclusão: Conclui-se que os profissionais da saúde mantiveram altos níveis de automedicação durante a pandemia da COVID-19, quando comparado com a literatura pré-COVID-19.
Genomic analysis of chromosomal cointegrated blaNDM-1-carrying ICE and blaRSA-1-carrying IME from clinical multidrug resistant Aeromonas caviae
Authors: Luo Xinhua , Yin Zhe , Yu Lianhua , Zhang Jin , Hu Dakang , Xu Mengqiao , Wang Peng , Wang Fengling , Feng Jiao 
Published: March 2023

IntroductionThe objective of this study is to thoroughly analyze the detailed genomic characteristics of clinical strain 211703 of Aeromonas caviae, which co-carrying blaRSA-1 and blaNDM-1 genes. 211703 was isolated from the patient’s cerebrospinal fluid drainage sample in a Chinese tertiary hospital.MethodsCarbapenemase NDM was detected by the immunocolloidal gold technique. The MIC values were determined by VITEK2. The whole genome sequence of 211703 was analyzed using phylogenetics, genomic comparison, and extensive dissection.ResultsThis study revealed that 211703 only contained a single 4.78 Mb chromosome (61.8% GC content), and no plasmids were discovered in 211703. 15 different types of resistant genes were detected in the genome of 211703, including blaRSA-1 harbored on integrative and mobilizable element (IME) Tn7413a, and blaNDM-1 harbored on integrative and conjugative element (ICE). The ICE and IME were all carried on the chromosome of 211703 (c211703). Detailed comparison of related IMEs/ICEs showed that they shared similar conserved backbone regions, respectively. Comprehensive annotation revealed that blaRSA-1 was carried by the gene cassette of a novel integron In2148 on Tn7413a, and blaNDM-1 was captured by an insertion sequence ISCR14-like on the ICE of 211703. We speculated that mobile genetic elements (MGEs) such as ICE and IME facilitated the spread of resistance genes such as blaRSA-1 and blaNDM-1.DiscussionIn conclusion, this study provides an overall understanding of the genomic characterization of clinically isolated A. caviae 211703, and an in-depth discussion of multiple acquisition methods of drug resistance genes in Aeromonas. To the best of our knowledge, this is the first report of A. caviae carrying blaRSA-1 even both blaRSA-1 and blaNDM-1, and this is the first bacterium carrying blaRSA-1 isolated from the clinical setting.
Elevated albumin corrected anion gap is associated with poor in-hospital prognosis in patients with cardiac arrest: A retrospective study based on MIMIC-IV database
Authors: Hu Beiping , Zhong Lei , Yuan Meng , Min Jie , Ye Lili , Lu Jianhong , Ji Xiaowei 
Published: March 2023

BackgroundCardiac arrest(CA) is one of the most leading causes of death. Most of the indicators which used to predict the prognosis of patients with CA are not recognized. Previous studies have suggested that albumin corrected anion gap (ACAG) is associated with recovery of spontaneous circulation in patients with CA, but the predictive value of ACAG for prognosis has not been investigated. This study aims to explore the relationship between ACAG and prognosis during hospitalization in patients with CA.MethodsThe baseline data of adult patients with CA hospitalized in the intensive care unit (ICU) from 2008 to 2019 in the American Intensive Care Database (MIMIC-IV, version v2.0) were collected. According to the in-hospital prognosis, patients were divided into survival and non-survival group. Based on the criteria of ACAG level in the previous literature, patients enrolled were divided into normal ACAG (12–20 mmol/L) and high ACAG (&gt;20 mmol/L) group. The basic information of patients during hospitalization were compared and analyzed between the two groups with propensity score matching (PSM). The Kaplan-Meier method was used to compare the cumulative survival rates of normal ACAG and high ACAG groups before and after matching. Restricted cubic spline (RCS) method and multivariate COX proportional hazards regressions were used to analyze whether elevated ACAG was associated with all-cause mortality during hospitalization.ResultsA total of 764 patients were included. A matched cohort (n = 310) was obtained after PSM analysis. The mortality rate before and after matching in the high ACAG group was higher than that in the normal ACAG group (χ2 = 25.798; P &lt; 0.001; χ2 = 6.258; P = 0.012) The Kaplan-Meier survival analysis before and after matching showed that the cumulative survival rate of the high ACAG group was lower (P &lt; 0.05). RCS analysis showed that ACAG had a non-linear relationship with the risk of in-hospital all-cause mortality (χ2 = 6.060, P &lt; 0.001). Multivariate COX regression analysis before and after PSM suggested that elevated ACAG was an independent risk factor for all-cause mortality in patients with CA during hospitalization (P &lt; 0.01).ConclusionsElevated ACAG is associated with increased all-cause mortality in patients with CA during hospitalization, it can be an independent risk factor for poor prognosis in patients with CA and remind clinicians to pay more attention to these patients.
Prediction models for cardiovascular disease risk among people living with HIV: A systematic review and meta-analysis
Authors: Yu Junwen , Liu Xiaoning , Zhu Zheng , Yang Zhongfang , He Jiamin , Zhang Lin , Lu Hongzhou 
Published: March 2023

BackgroundHIV continues to be a major global health issue. The relative risk of cardiovascular disease (CVD) among people living with HIV (PLWH) was 2.16 compared to non-HIV-infections. The prediction of CVD is becoming an important issue in current HIV management. However, there is no consensus on optional CVD risk models for PLWH. Therefore, we aimed to systematically summarize and compare prediction models for CVD risk among PLWH.MethodsLongitudinal studies that developed or validated prediction models for CVD risk among PLWH were systematically searched. Five databases were searched up to January 2022. The quality of the included articles was evaluated by using the Prediction model Risk Of Bias ASsessment Tool (PROBAST). We applied meta-analysis to pool the logit-transformed C-statistics for discrimination performance.ResultsThirteen articles describing 17 models were included. All the included studies had a high risk of bias. In the meta-analysis, the pooled estimated C-statistic was 0.76 (95% CI: 0.72–0.81, I2 = 84.8%) for the Data collection on Adverse Effects of Anti-HIV Drugs Study risk equation (D:A:D) (2010), 0.75 (95% CI: 0.70–0.79, I2 = 82.4%) for the D:A:D (2010) 10-year risk version, 0.77 (95% CI: 0.74–0.80, I2 = 82.2%) for the full D:A:D (2016) model, 0.74 (95% CI: 0.68–0.79, I2 = 86.2%) for the reduced D:A:D (2016) model, 0.71 (95% CI: 0.61–0.79, I2 = 87.9%) for the Framingham Risk Score (FRS) for coronary heart disease (CHD) (1998), 0.74 (95% CI: 0.70–0.78, I2 = 87.8%) for the FRS CVD model (2008), 0.72 (95% CI: 0.67–0.76, I2 = 75.0%) for the pooled cohort equations of the American Heart Society/ American score (PCE), and 0.67 (95% CI: 0.56–0.77, I2 = 51.3%) for the Systematic COronary Risk Evaluation (SCORE). In the subgroup analysis, the discrimination of PCE was significantly better in the group aged ≤40 years than in the group aged 40–45 years (P = 0.024) and the group aged ≥45 years (P = 0.010). No models were developed or validated in Sub-Saharan Africa and the Asia region.ConclusionsThe full D:A:D (2016) model performed the best in terms of discrimination, followed by the D:A:D (2010) and PCE. However, there were no significant differences between any of the model pairings. Specific CVD risk models for older PLWH and for PLWH in Sub-Saharan Africa and the Asia region should be established.Systematic Review Registration: PROSPERO CRD42022322024.
A parallel numerical algorithm by combining MPI and OpenMP programming models with applications in gravity field recovery
Authors: Lu Biao , Luo Zhicai , Zhong Bo , Zhou Hao 
Published: March 2023

Satellite gravimetry missions have enabled the calculation of high-accuracy and high-resolution Earth gravity field models from satellite-to-satellite tracking data and gravitational gradients. However, calculating high maximum degree/order (e.g., 240 or even higher) gravity field models using the least squares method is time-consuming due to the vast amount of gravimetry observations. To improve calculation efficiency, a parallel algorithm has been developed by combining Message Passing Interface (MPI) and Open Multi-Processing (OpenMP) programming models to calculate and invert normal equations for the Earth gravity field recovery. The symmetrical feature of normal equations has been implemented to speed up the calculation progress and reduce computation time. For example, the computation time to generate the normal equation of an IGGT_R1 test version of degree/order 240 was reduced from 88 h to 27 h by considering the symmetrical feature. Here, the calculation was based on the high-performance computing cluster with 108 cores in the School of Geodesy and Geomatics, at Wuhan University. Additionally, the MPI parallel Gaussian-Jordan elimination method was modified to invert normal equation matrices and scaled up to 100 processor cores in this study while the traditional method was limited in a certain number of processors. Furthermore, the Cholesky decomposition from the ScaLAPACK library was used to compare with the parallel Gauss-Jordan elimination method. The numerical algorithm has effectively reduced the amount of calculation and sped up the calculation progress, and has been successfully implemented in applications such as building the gravity field models IGGT_R1 and IGGT_R1C.
Education quality and student satisfaction nexus using instructional material, support, classroom facilities, equipment and growth: Higher education perspective of Pakistan
Authors: Ikram Maryam , Kenayathulla Husaina Banu 
Published: March 2023

PurposeThe primary purpose is to examine the impact between education quality (EQ) and student satisfaction (SS) in terms of instructional materials, support, classroom facilities and equipment, and growth in Pakistani private higher education institutes.Design/methodology/approachThis study utilized correlation-focused quantitative research by randomly distributing a 54-item questionnaire to 440 postgraduate students in Pakistan’s private higher education institutions (HEIs). SPSS (V.23) and PLS-SEM (V.3.3.3) were employed to investigate the data.FindingsThe findings demonstrate that EQ has a direct and significant positive effect on student satisfaction with instructional materials, support, classroom facilities and equipment, and growth in private higher education institutions.Research implicationsThe current study will help policymakers, the Higher Education Commission (HEC), and institutions to pay greater attention to the significance of education quality indicators in making a difference in higher education, which may contribute to student satisfaction. In addition, their efforts will significantly contribute to the nation’s progress. Furthermore, it will contribute to the betterment of the world by accomplishing the sustainable development goal of quality education set by the United Nations. The recent findings will also have far-reaching advantages for society, demonstrating the positive effects that high-quality education may have on a nation’s progress by creating competent and productive students.LimitationsOnly private universities in Pakistan’s higher education sector were considered for this study, and students enrolled in post-graduate degrees were the subjects of this investigation. This study was restricted to testing in only one province, Punjab, Pakistan. Another limitation of this study is that it is based on a research framework deduced from previous underpinnings and literature.OriginalityThese findings contribute to the existing area of research on the direct and significant effects of EQ on SS in HEIs. These findings may positively impact student satisfaction in private higher education institutions. The findings can guide higher education institutions (HEIs) regarding the importance of EQ in achieving desirable student satisfaction (SS). Because the Higher Education Commission (HEC) efforts will contribute considerably to the growth of higher education institutions (HEIs) and the nation, this study is vital for policymakers and practitioners working in higher education.
Non-linear association of fasting C-peptide and uric acid levels with renal dysfunction based on restricted cubic spline in patients with type 2 diabetes: A real-world study
Authors: Chen Lu , Hu Yifei , Ma Yongjun , Wang Huabin 
Published: March 2023

BackgroundPrevious studies had showed divergent findings on the associations of C-peptide and/or uric acid (UA) with renal dysfunction odds in patients with type 2 diabetes mellitus (T2DM). We hypothesized that there were non-linear relationships between C-peptide, UA and renal dysfunction odds. This study aimed to further investigate the relationships of different stratification of C-peptide and UA with renal dysfunction in patients with T2DM.MethodWe conducted a cross-sectional real-world observational study of 411 patients with T2DM. The levels of fasting C-peptide, 2h postprandial C-peptide, the ratio of fasting C-peptide to 2h postprandial C-peptide (C0/C2 ratio), UA and other characteristics were recorded. Restricted cubic spline (RCS) curves was performed to evaluated the associations of stratified C-peptide and UA with renal dysfunction odds.ResultsFasting C-peptide, C0/C2 ratio and UA were independently and significantly associated with renal dysfunction in patients with T2DM as assessed by multivariate analyses (p &lt; 0.05). In especial, non-linear relationships with threshold effects were observed among fasting C-peptide, UA and renal dysfunction according to RCS analyses. Compared with patients with 0.28 ≤ fasting C-peptide ≤ 0.56 nmol/L, patients with fasting C-peptide &lt; 0.28 nmol/L (OR = 1.38, p = 0.246) or fasting C-peptide &gt; 0.56 nmol/L (OR = 1.85, p = 0.021) had relatively higher renal dysfunction odds after adjusting for confounding factors. Similarly, compared with patients with 276 ≤ UA ≤ 409 μmol/L, patients with UA &lt; 276 μmol/L (OR = 1.32, p = 0.262) or UA &gt; 409 μmol/L (OR = 6.24, p &lt; 0.001) had relatively higher odds of renal dysfunction.ConclusionThe renal dysfunction odds in patients with T2DM was non-linearly associated with the levels of serum fasting C-peptide and UA. Fasting C-peptide and UA might have the potential role in odds stratification of renal dysfunction.