bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transparent Oil–Water Separating Spiky SiO2 Nanoparticle Supramolecular Polymer Superhydrophobic Coatings
Authors: Nguyen Nguyen Binh , Ly Nguyên Hoàng , Tran Huynh Nhu , Son Sang Jun , Joo Sang‐Woo , Vasseghian Yasser , Osman Sameh M. , Luque Rafael 
Published: January 2023

AbstractA potential application of spiky SiO2 nanoparticles (NPs) with tubular and rough surfaces is investigated as superhydrophobic coatings, for their unique transparent, fluorinate‐free, and environmentally friendly properties. This study demonstrates a facile method for the successful fabrication of superhydrophobic coatings and SiO2@polydimethylsiloxane (PDMS) using spiky SiO2 NPs, N‐coordinated boroxines, and PDMS. Combined with spray coating technology, this method of superhydrophobic coating can be simply applied to both hydrophilic and hydrophobic surfaces, including wood, fabric, glass, metal, sponge, and paper. The nanocomposite coating on the glass surface showed both excellent superhydrophobicity and high transparency, with a contact angle of 165.4 ± 1.0° and 96.93% transmittance at 550 nm, respectively. SiO2@PDMS‐modified glass substrate is found to be resilient to UV irradiation, water, and high temperature treatments at ambient conditions. Experimental data demonstrated that the simple but effective combination of N‐boroxine‐PDMS and spiky SiO2 NPs produces a layered coating material that exhibits many good integrated surface properties, including stability, transparency, superhydrophobicity, and oil–water separation.
Indigenous systems knowledge applied to protocols for governance and inquiry
Authors: Fletcher Gabrielle , Waters Joshua , Yunkaporta Tyson , Marshall Chels , Davis John , Manning Bancroft Jack 
Published: January 2023

AbstractThis paper details the progress to date of the Indigenous Knowledge Systems Lab (IKS Lab) at Deakin University in establishing organisational processes and methods of inquiry grounded in Indigenous protocols. Continuity of traditional knowledge and practice in the Lab requires a deep‐time perspective of complex systems both local and nonlocal, ensuring that ancient psycho‐technologies are retrieved forward for context‐dependent, collectively responsive thought leadership and projects stewarding relational systems increase during phase shifts anticipated from future inflection points of wicked proportions. This work requires abductive reasoning, the eradication of discrete discipline boundaries, continuous adaptive responsiveness, distributed authority, agentic dyads of individual and group sovereignties, kinship protocols for solitary/pair/group/multigroup activity, traditional embassy protocols for dialogue between diverse systems and traditional Law‐based principles translated into propositions that can inform innovative systems functions and theory.
Structure‐property relationships of waterborne polyurethane (WPU) in aqueous formulations
Authors: Patti Antonella , Acierno Domenico 
Published: January 2023

AbstractThis study provides an overview of the rheological properties of aqueous polyurethanes (WPU), as the main component, or as a thickening additive in aqueous formulations. Waterborne polyurethanes (WPU) have been proposed as an environmentally friendly alternative to conventional solvent‐based solutions in a variety of industrial applications such as coatings, adhesives, inks. In all these fields, the control of rheological properties became an important prerogative to determine the quality of the dispersion and its potential applicability. First, the effect of parameters such as components, particle size and content, temperature, and interactions on dispersion viscosity was reported. Then, the effect of two additives, i.e. thickeners and nanomaterials, on structure–property relationships of WPU‐base systems, was described. Thickeners are rheological modifiers, commonly used to stabilize the dispersion and prevent flocculation and sedimentation of the particles, or to change the flow behavior of dispersions from Newtonian to pseudoplastic. These species can interact with water and polymer particles to create a network structure that alters the flow resistance, and thus viscosity. The use of hyperbranched aqueous polyurethane as thickening agent in WPU formulations was also presented. On the other hand, nanostructured fillers (0D/1D/2D) or a combination thereof in waterborne polyurethane led to the formation of specific microstructures that prevented the penetration of water, oxygen, and corrosive substances, also improved mechanical and thermal properties, allowing the development of high‐performance WPU‐based products.
Clinical resolution of systemic mycobacterial infection in a cat with a suspected spinal granuloma
Authors: Martín‐Ambrosio Francés Marina , Pradel Julie , Domínguez Elisabet , Sharman Mellora 
Published: January 2023

AbstractAn 8‐year‐old, female, spayed, domestic longhair cat presented with progressive pelvic limb weakness, lethargy and weight loss. Physical examination identified bilateral pelvic limb proprioceptive ataxia, tachypnoea and a subcutaneous nodular lesion on the left flank. Investigations documented a diffuse broncho‐interstitial and nodular pulmonary pattern, pyogranulomatous inflammation in the spleen and an intradural‐extramedullary spinal lesion at the level of L3. Mycobacterium microti was confirmed based on demonstration of organisms on histopathology of the subcutaneous nodule using Ziehl–Neelsen stain together with positive polymerase chain reaction and interferon‐gamma release assay results. Therapy with rifampicin, azithromycin and pradofloxacin was administered for 7 months. Serial monitoring, including repeated magnetic resonance imaging, demonstrated resolution of the clinical signs, pulmonary, subcutaneous and spinal lesions.
Wastewater treatment plants discharges disseminated more Giardia than Cryptosporidium
Authors: Onursal Asli , Icgen Bulent 
Published: January 2023

AbstractParasitic protozoa Giardia intestinalis and Cryptosporidium parvum are causative agents for giardiasis and cryptosporidiosis, respectively. These infections are mostly associated with waterborne diseases. The discharges from wastewater treatment plants (WWTPs) that reach surface waters cause waterborne transmission because there are no regulations for monitoring these protozoa. This emphasizes how crucial the removal capacities of WWTPs to prevent the spread of infectious parasitic pathogens. For this reason, in this study, five different types of WWTPs including conventional activated sludge (CAS), biological nutrient removal (BNR), sequencing batch reactor (SBR), membrane bioreactor (MBR), and WWTP with coagulation–flocculation and UV disinfection (CoFlUV) units were investigated over a year, seasonally in terms of their G. intestinalis and C. parvum removal capacities. The seasonal abundances of these protozoa‐specific genes in both the influents and effluents of each WWTP were determined by qPCR. The reduction of protozoan rDNA copies in the effluent wastewater samples compared with the influent wastewater samples was assessed as log10 reduction values (LRVs). LRVs >3 were reachable for C. parvum in all types of WWTPs tested. However, only LRVs 1–2 were reachable for G. intestinalis in CAS, SBR, CoFlUV, and MBR. Significant seasonal variations were just observed in SBR and CAS for G. intestinalis and C. parvum (p < 0.05), respectively. The findings depicted that WWTPs tested disseminated more giardiasis causative agents than cryptosporidiosis. Therefore, G. intestinalis needs to be monitored in WWTPs' discharges to reduce any potential damage of this parasite to public health.Practitioner Points

Removal of G. intestinalis and C. parvum in WWTPs was affected by the process.
LRV 2.92 was the highest LRV achieved for G. intestinalis.
LRV >3 was reachable for C. parvum.
WWTPs discharges disseminated more G. intestinalis than C. parvum.
WWTPs effluents should be monitored in terms of G. intestinalis.
Alkaline‐earth metal dimesitylphosphinites and their ether adducts – A structural study in solution and in the crystalline state
Authors: Fener Benjamin E. , Schüler Philipp , Görls Helmar , Liebing Phil , Westerhausen Matthias 
Published: January 2023

AbstractAlkaline‐earth metalation of dimesitylphosphane oxide Mes2P(O)H (1) in ethereal solvents with dialkylmagnesium and alkylmagnesium bromide as well as the homoleptic bis(trimethylsilyl)amides of calcium, strontium, and barium yields [(L)MgR(μ‐OPMes2)]2 (L/R=thf/Et (2‐Et), Et2O/Br (2‐Br)), [(thf)3Ca(hmds)(OPMes2)] (3‐hmds), [(thf)3Mg(OPMes2)2] (2‐thf) and [(thf)4Ae(OPMes2)2] (Ae=Ca (3‐thf), Sr (4‐thf), and Ba (5‐thf)), depending on the applied stoichiometry. Exchange of thf ligands in 3‐thf by oligodentate ethers allows isolation of [(thf)2(dme)Ca(OPMes2)2] (3‐dme), [(thf)2(diglyme)Ca(OPMes2)2] (3‐diglyme) and [(thf)(triglyme)Ca(OPMes2)2] (3‐triglyme). Contrary to this finding, oligodentate amines are unable to substitute ligated thf ligands in 3‐thf. In ethereal solutions, the heteroleptic complexes 2‐Et, 2‐Br and 3‐hmds show Schlenk‐type equilibria, interconverting these compounds into their homoleptic counterparts.
Challenges and Opportunities of Computational Social Science for Official Statistics
Authors: Signorelli Serena , Fontana Matteo , Gabrielli Lorenzo , Vespe Michele 
Published: January 2023

AbstractThe vast amount of data produced everyday (so-called digital traces) and available nowadays represent a gold mine for the social sciences, especially in a computational context, that allows to fully extract their informational and knowledge value. In the latest years, statistical offices have made efforts to profit from harnessing the potential offered by these new sources of data, with promising results. But how difficult is this integration process? What are the challenges that statistical offices would likely face to profit from new data sources and analytical methods? This chapter will start by setting the scene of the current official statistics system, with a focus on its fundamental principles and dimensions relevant to the use of non-traditional data. It will then present some experiments and proofs of concept in the context of data innovation for official statistics, followed by a discussion on prospective challenges related to sustainable data access, new technical and methodological approaches and effective use of new sources of data.
Towards a More Sustainable Mobility
Authors: Pallonetto Fabiano 
Published: January 2023

AbstractThe transport sector is the second most important source of emissions in the EU. It is paramount to act now towards the decarbonisation of our transport system to mitigate climate change effects. Waiting for future technological advancements to minimise the existing anthropogenic emissions and dramatically boost its sustainability is risky for human survival. The current chapter highlights how the path towards a sustainable transport system is a whole stakeholders’ effort involving the mass deployment of available technology, changing user behaviours, data-driven legislation, and researching and developing future disruptive technologies. The author analyses and classifies the available data on various transport modals and assesses the impact of the technologies and policy measures in terms of potential reduction of carbon emissions, challenges, and opportunities. It also exemplifies outstanding test settings across the world on how already available technologies have contributed to the development of a lower-carbon transport setting. The chapter considers developing countries’ economic and infrastructural challenges in upgrading to a low-carbon transport system and the lack of data-driven decisions and stakeholders’ engagement measures in addressing the sector sustainability challenges. It also emphasised how a sustainable transport system should lay the foundation on data harmonisation and interoperability to accelerate innovation and promote a fast route for deploying new and more effective policies.
Natural Language Processing for Policymaking
Authors: Jin Zhijing , Mihalcea Rada 
Published: January 2023

AbstractLanguage is the medium for many political activities, from campaigns to news reports. Natural language processing (NLP) uses computational tools to parse text into key information that is needed for policymaking. In this chapter, we introduce common methods of NLP, including text classification, topic modelling, event extraction, and text scaling. We then overview how these methods can be used for policymaking through four major applications including data collection for evidence-based policymaking, interpretation of political decisions, policy communication, and investigation of policy effects. Finally, we highlight some potential limitations and ethical concerns when using NLP for policymaking.
Das Netzwerk Universitätsmedizin: Technisch-organisatorische Ansätze für Forschungsdatenplattformen
Authors: Heyder Ralf ,   NUM Coordination Office, Kroemer Heyo K. , Wiedmann Silke , Pley Christina , Heyer Carolin , Heuschmann Peter , Vehreschild Jörg Janne , Krefting Dagmar , Illig Thomas , Nauck Matthias , Schaller Jens , Kraus Monika , Hoffmann Wolfgang , Stahl Dana , Hanß Sabine , Anton Gabriele , Schäfer Christian , Reese Jens-Peter , Hopff Sina M. , Lorbeer Roberto , Lorenz-Depiereux Bettina , Prokosch Hans-Ulrich , Zenker Sven , Eils Roland , Bucher Andreas , Kleesiek Jens , Vogl Thomas , Hamm Bernd , Penzkofer Tobias , Schirrmeister Wiebke , Röhrig Rainer , Walcher Felix , Majeed Raphael , Erdmann Bernadett , Scheithauer Simone , Grundmann Hajo , Dilthey Alexander , Bludau Anna ,   NUKLEUS Study Group,   NUM-RDP Coordination,   RACOON Coordination,   AKTIN Coordination,   GenSurv Study Group
Published: January 2023

ZusammenfassungDas Netzwerk Universitätsmedizin (NUM) besteht aus den 36 Standorten der Universitätsmedizin in Deutschland. Der Auftrag ist die Koordinierung der universitätsmedizinischen COVID-19-Forschung auf nationaler Ebene. Dazu werden u. a. gemeinsame Infrastrukturen für die Sammlung, Haltung und Nutzung medizinischer Forschungsdaten benötigt. Diese standen beim Start des NUM-Projekts im April 2020 nicht im erforderlichen Rahmen zur Verfügung. Medizinische Forschungsdaten sind extrem heterogen und gehen weit über „Real World Data“ (Daten aus dem Versorgungsalltag) hinaus. Eine universelle Lösung dafür gab es nicht, deshalb hat das NUM fünf Forschungsinfrastrukturen für unterschiedliche Datenarten, unterschiedliche Wege der Datengewinnung und unterschiedliche Datenentstehungssettings aufgebaut. Um die Bildung neuer Datensilos zu verhindern, arbeiten alle fünf Infrastrukturen auf Basis der FAIR-Prinzipien, nach denen Daten auffindbar (findable), zugänglich (accessible), interoperabel (interoperable) und wiederverwendbar (reusable) sein sollen. Zudem implementiert das NUM einen übergreifenden Steuerungsrahmen (Governance Framework), um die Weiterentwicklung dieser fünf Infrastrukturen zentral zu steuern. Der Artikel beschreibt den aktuellen Stand der Infrastrukturentwicklung im NUM und mögliche Perspektiven. Ein starker Fokus wird dabei auf die technisch-organisatorischen Grundlagen gerichtet.
LINC01004-SPI1 axis-activated SIGLEC9 in tumor-associated macrophages induces radioresistance and the formation of immunosuppressive tumor microenvironment in esophageal squamous cell carcinoma
Authors: Zhao Fen , Tian Hui , Wang Yungang , Zhang Jianbo , Liu Fang , Fu Lei 
Published: January 2023

AbstractRadioresistance and immunosuppression remain the major obstacles in the anti-cancer treatments. This work studies the functions of sialic acid binding Ig like lectin 9 (SIGLEC9) and its related molecules in radioresistance and immunosuppression in esophageal squamous cell carcinoma (ESCC). The single-cell analysis showed that SIGLEC9 was mainly expressed on tumor-associated macrophages (TAMs). Monocytes-derived macrophages were co-cultured with ESCC cells and subjected to radiotherapy. High or low doses of radiotherapy induced SIGLEC9 upregulation and M2 polarization of TAMs. Artificial inhibition of SIGLEC9 in TAMs suppressed the radioresistance and immunosuppressive tumor microenvironment (TME) in the co-cultured ESCC cells. Upstream molecules of SIGLEC9 were predicted via bioinformatics. LINC01004 recruited Spi-1 proto-oncogene (SPI1) in nucleus of TAMs to induce transcriptional activation of SIGLEC9. SIGLEC9 interacted with mucin 1 (MUC1). MUC1 overexpression in ESCCs induced M2 skewing of TAMs, enhanced radioresistance and immunosuppression, and promoted nuclear translocation of β-catenin to suppress radiotherapy-induced ferroptosis of ESCC cells. These effects were blocked upon SIGLEC9 suppression. In vitro results were reproduced in the animal models with xenograft tumors. Taken together, this study demonstrates that the LINC01004-SPI1 axis-activated SIGLEC9 in TAMs induces radioresistance and the formation of immunosuppressive TME in ESCC.
Prevalence and pattern of focal and potential diffuse myocardial fibrosis in male and female marathon runners using contrast-enhanced cardiac magnetic resonance
Authors: Ragab Haissam , Lund Gunnar K. , Breitsprecher Lynn , Sinn Martin R. , Muellerleile Kai , Cavus Ersin , Stehning Christian , Tahir Enver , Blankenberg Stefan , Patten Monica , Pressler Axel , Adam Gerhard , Avanesov Maxim 
Published: January 2023

Abstract
Objectives
This study analyzed the prevalence and pattern of focal and potential diffuse myocardial fibrosis detected by late gadolinium enhancement (LGE) and extracellular volume (ECV) imaging in male and female marathon runners using cardiac magnetic resonance (CMR).

Methods
Seventy-four marathon runners were studied including 55 males (44 ± 8 years) and 19 females (36 ± 7 years) and compared to 36 controls with similar age and sex using contrast-enhanced CMR, exercise testing, and blood samples.

Results
Contrast-enhanced CMR revealed focal myocardial fibrosis in 8 of 74 runners (11%). The majority of runners were male (7 of 8, 88%). LGE was typically non-ischemic in 7 of 8 runners (88%) and ischemic in one runner. ECV was higher in remote myocardium without LGE in male runners (25.5 ± 2.3%) compared to male controls (24.0 ± 3.0%, p < 0.05), indicating the potential presence of diffuse myocardial fibrosis. LV mass was higher in LGE + males (86 ± 18 g/m2) compared to LGE- males (73 ± 14 g/m2, p < 0.05). Furthermore, LGE + males had lower weight (69 ± 9 vs 77 ± 9 kg, p < 0.05) and shorter best marathon finishing times (3.2 ± 0.3 h) compared to LGE- males (3.6 ± 0.4 h, p < 0.05) suggesting higher training load in these runners to accomplish the marathon in a short time.

Conclusion
The high frequency of non-ischemic myocardial fibrosis in LGE + male runners can be related to increased LV mass in these runners. Furthermore, a higher training load could explain the higher LV mass and could be one additional cofactor in the genesis of myocardial fibrosis in marathon runners.

Key Points
• A high frequency of myocardial fibrosis was found in marathon runners.
• Myocardial fibrosis occurred typically in male runners and was typically non-ischemic.
• Higher training load could be one cofactor in the genesis of myocardial fibrosis in marathon runners.
Effect of herbivore load on VOC-mediated plant communication in potato
Authors: Vázquez-González Carla , Quiroga Violeta , Martín-Cacheda Lucía , Rasmann Sergio , Röder Gregory , Abdala-Roberts Luis , Moreira Xoaquín 
Published: January 2023

Abstract
Main conclusion
VOC emissions increased with herbivore load, but this did not result in concomitant increases in resistance in neighbouring plants, suggesting that communication occurred independently of herbivore load in emitter plants.

Abstract
Herbivore-damaged plants emit volatile organic compounds (VOCs) that can alert neighbours and boost their resistance. While VOC-mediated plant communication has been shown to be herbivore-specific, we know little about its contingency on variation in herbivore load. To address this knowledge gap, we tested herbivore load effects on VOC-mediated communication between potato plants (Solanum tuberosum) using the generalist herbivore Spodoptera exigua. First, we tested whether herbivore load (three levels: undamaged control, low, and high load) affected total VOC emissions and composition. Second, we matched emitter and receiver plants and subjected emitters to the same herbivore load treatments. Finally, we performed a bioassay with S. exigua on receivers to test for induced resistance due to VOC-mediated communication. We found that herbivory significantly increased total VOC emissions relative to control plants, and that such increase was greater under high herbivore load. In contrast, we found no detectable effect of herbivory, regardless of the load, on VOC composition. The communication experiment showed that VOCs released by herbivore-induced emitters boosted resistance in receivers (i.e., lower leaf damage than receivers exposed to VOCs released by control emitters), but the magnitude of such effect was similar for both levels of emitter herbivore load. These findings suggest that changes in VOCs due to variation in herbivore load do not modify the outcomes of plant communication.
Endoscopic fully covered self-expandable metal stent and vacuum-assisted drainage to treat postoperative colorectal cancer anastomotic stenosis with fistula
Authors: Deng Shenghe , Liu Ke , Gu Junnan , Cao Yinghao , Mao Fuwei , Xue Yifan , Jiang Zhenxing , Qin Le , Wu Ke , Cai Kailin 
Published: January 2023

AbstractBackgroundDigestive tract reconstruction is required after the surgical resection of a colorectal malignant tumor. Some patients may have concomitant anastomotic complications, such as anastomotic stenosis with fistula (ASF), postoperatively. Therefore, we evaluated the efficacy and safety of endoscopic fully covered self-expandable metal stent and homemade vacuum sponge-assisted drainage (FSEM-HVSD) for the treatment of ASF following the radical resection of colorectal cancer.MethodsPatients treated with FESM-HVSD were prospectively analyzed and followed up for ASF following colorectal cancer treatment in our medical center from 2017 to 2021 for the observation and evaluation of its safety and efficacy.ResultsFifteen patients with a mean age of 55.80 ± 11.08 years were included. Nine patients (60%) underwent protective ileostomy. All 15 patients were treated with endoscopic FSEM-HVSD. The median time from the index operation to the initiation of FSEM-HVSD was 80 ± 20.34 days in patients who underwent protective ileostomy versus 11.4 ± 4.4 days in those who did not. The average number of endoscopic treatments per patient was 5.70 ± 1.25 times. The mean length of hospital stay was 27.60 ± 4.43 days. FSEM-HVSD treatment was successful in 13 patients, and no patients had any complications. The follow-up time was 1 year. Twelve of 15 (80%) patients achieved prolonged clinical success after FSEM-HVSD treatment, 1 experienced anastomotic tumor recurrence and underwent surgery again, and 1 patient required balloon dilation for anastomotic stenosis recurrence.ConclusionsFSEM-HVSD is an effective, safe, and minimally invasive treatment for ASF following colorectal cancer treatment. This technique could be the preferred treatment strategy for patients with ASF.