bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical characteristics and outcomes of community acquired-acute kidney injury
Authors: Tso Maggie , Sud Kamal , Van Connie , Tesfaye Wubshet , Castelino Ronald L. 
Published: March 2023

Abstract
Purpose
Published works have reported the impact of a nephrologist intervention on outcomes for patients with hospital-acquired acute kidney injury (HA-AKI), however little is known about the clinical characteristics of patients with community-acquired acute kidney injury (CA-AKI) and the impact of nephrology interventions on outcomes in these patients.

Methods
A retrospective study on all adult patients admitted to a large tertiary care hospital in 2019 who were identified to have CA-AKI were followed from hospital admission to discharge. Clinical characteristics and outcomes of these patients were analysed by receipt of nephrology consultation. Statistical analysis included descriptive, simple Chi-squared/Fischer Exact test, independent samples t-test/Mann–Whitney U test and logistic regression.

Results
182 patients fulfilled the study inclusion criteria. Mean age was 75 ± 14 years, 41% were female, 64% had stage 1 AKI on admission, 35% received nephrology input and 52% had achieved recovery of kidney function by discharge. Higher admission and discharge serum creatinine (SCr) (290.5 vs 159 and 173 vs 109 µmol/L respectively, p =  < 0.001), and younger age (68 vs 79, p =  < 0.001) were associated with nephrology consultations, whilst length of hospitalisation, mortality and rehospitalisation rates were not significantly different between the two groups. At least 65% were recorded to be on at least one nephrotoxic medication.

Conclusion
Our findings provide a snapshot of current practice where close to two-thirds of hospitalised patients with CA-AKI had a mild form of AKI that was associated with good clinical outcomes. While higher SCr on admission and younger age were predictors of receiving a nephrology consultation, nephrology consultations did not have any impact on outcomes.
The dynamics of neutralizing antibodies against SARS-CoV-2 in cats naturally exposed to virus reveals an increase in antibody activity after re-infection
Authors: Villanueva-Saz Sergio , Martínez Marivi , Rueda Pablo , Bolea Sara , Pérez María Dolores , Verde Maite , Yzuel Andrés , Hurtado-Guerrero Ramón , Pardo Julián , Santiago Llipsy , Fernández Antonio , Arias Maykel 
Published: March 2023

AbstractSevere Acute Respiratory Syndrome Coronavirus 2 is the causative agent of Coronavirus Disease 2019 in humans. To date, little is known about the persistence of antibodies against SARS-CoV-2 in animals under natural conditions, in particular susceptible pets such as cat. This study reports the detection and monitoring of the humoral response against SARS-CoV-2 including the detection of immunoglobulins G specific for receptor binding domain of SARS-CoV-2 spike protein by an enzyme-linked immunosorbent assay and neutralizing antibodies by virus neutralization assay. Results showed that these antibodies last longer than 16 months in two naturally apparently healthy infected cats with the absence of clinicopathological findings during the follow-up. Moreover, re-infection is also possible with an important increase in virus neutralization test titers in both animals with no evident systemic signs found during each physical examination and with values of hematologic and biochemical parameters inside the normal reference intervals. Our results confirm a slow but progressive decrease of the kinetics and immunity of neutralizing antibodies in cats after the infection. Furthermore, similar to humans SARS-CoV-2 reinfection can stimulate an increase of the neutralizing antibodies determined by these two serological techniques in domestic cats.
Improved 3D localization algorithm for large scale wireless sensor networks
Authors: Mani Rahma , Rios-Navarro Antonio , Sevillano-Ramos Jose-Luis , Liouane Noureddine 
Published: March 2023

AbstractAs localization represents the main core of various wireless sensor network applications, several localization algorithms have been suggested in wireless sensor network research. In this article, we put forward an iterative bounding box algorithm enhanced by a Kalman filter to refine the unknown node’s estimated position. In fact, several research efforts are currently in progress to extend the 2D positioning algorithm in WSNs to 3D that reflects reality and the most practical applications. Subsequently, we replace a large number of GPS-equipped anchors with a single mobile anchor. In our studies, we consider the type of range-free sensor network exploiting the wireless sensors connectivity. We assess the performance of our algorithm using exhaustive experiments on several isotropic and anisotropic topologies. Our proposed algorithm can fulfill the joint goals of algorithm transparency and accuracy for various scenarios by evaluating parameters such as localization accuracy whilst changing other simulation parameters such as the effect of communication range, mobile anchor node position and sensor node deployment topology. It has been proven by the results of the experiments that the proposed algorithm effectively reduces the location error without requiring more equipment or increasing the communication cost.
A systematic literature review on greenwashing and its relationship to stakeholders: state of art and future research agenda
Authors: Santos Célia , Coelho Arnaldo , Marques Alzira 
Published: March 2023

AbstractThe interest in greenwashing has grown in recent decades. However, comprehensive, and systematic research concentrating on the evolution of this phenomenon, specifically regarding its impacts on stakeholders, is still needed. The main purpose of this study is to provide an overview and synthesis of the existing body of knowledge on greenwashing, through a bibliometric study of articles published up to 2021, identifying the most relevant research in this field. Special attention is given to the latest articles that link greenwashing to stakeholders, identifying gaps and future research opportunities. A bibliometric analysis and literature review was performed on 310 documents obtained from the Web of Science database, using the VOSviewer software program. This article identifies the most influential aspects of greenwashing literature (authors, articles, journals, institutions, and keyword networks). The most recent articles on the effect of greenwashing on stakeholders were also analyzed, which made it possible to identify trends, gaps, and opportunities for future research. These topics include greenwashing impacts on branding, consumer attitudes and intentions, mainly on purchase behavior, B2B relationships and the definition of taxonomy for greenwashing, considering the different practices. This study offers a thorough analysis on the state-of-the-art, as well as a closer look at the impacts of greenwashing on various stakeholders, providing a list of suggestions for future research.
Changes in testicular histomorphometry and ultrastructure of Leydig cells in adult male Japanese quail exposed to di (n-butyl) phthalate (DBP) during the prepubertal period
Authors: Bello Umar M. , Madekurozwa Mary-Cathrine , Groenewald Hermanus B. , Arukwe Augustine , Aire Tom A. 
Published: March 2023

AbstractPhthalate esters, such as di(n-butyl) phthalate, (DBP), are synthetic chemical pollutants commonly used as plasticizers in the manufacture of plastics. In the present study, we investigated the effects of DBP in the testes of adult male quails (Coturnix cortunix japonica) exposed by oral gavage to variable doses of DBP (0 [control], 1, 10, 50, 200, and 400 mg/kgbw−d), for 30 days during the prepubertal period, using histo-morphometric and ultrastructural techniques. Generally, significant decreases in seminiferous tubular diameter (STD) and epithelial height (SEH) were observed predominantly at the highest DBP doses (200 and 400 mg/kg), as compared to medium (50 mg/kg), and lowest doses (1 and 10 mg/kg) as well as the control group. Ultrastructurally, apparent dose-specific degenerative changes were observed in the Leydig cells. The lowest DBP doses (1 and 10 mg/kg) did not produce significant effects on Leydig cell ultrastructure, whereas, at the highest doses (200 and 400 mg/kg), the Leydig cells were remarkably conspicuous in the interstitium and appeared foamy. There was a preponderance of electron-lucent lipid droplets which crowded out the normal organelles of the cell, as well as increases in the number of dense bodies in the cytoplasm. The smooth endoplasmic reticulum (sER) was less obvious, compacted, and wedged between the abundant lipid droplets and mitochondria. Taken together, these findings indicate that pre-pubertal exposure of precocious quail birds to DBP, produced parameter-specific histometric tubular changes, as well as dose-dependent cyto-structural derangement of the Leydig cells; which consequently may lead to overt reproductive impairments in the adult bird in the environment.Graphical Abstract
Study on hydration mechanism and environmental safety of thermal activated red mud-based cementitious materials
Authors: Zhu Junge , Yue Hongzhi , Ma Laijun , Li Zichao , Bai Rong 
Published: March 2023

Abstract
Red mud (RM) cementitious materials were prepared with the thermally, thermoalkali- or thermocalcium-activated RM, steel slag (SS), and other additives. The effects of different thermal RM activation methods on the cementitious material hydration mechanisms, mechanical properties, and environmental risks were discussed and analyzed. The results showed that the hydration products of different thermally activated RM samples were similar with the main products being C-S–H, tobermorite, and Ca(OH)2. Ca(OH)2 was mainly present in thermally activated RM samples, and the tobermorite was mainly produced by samples prepared with thermoalkali- and the thermocalcium-activated RM. The mechanical properties of the samples prepared by thermally and thermocalcium-activated RM had early-strength properties, while the thermoalkali-activated RM samples were similar to the late-strength type of cement properties. The average flexural strength of thermally and the thermocalcium-activated RM samples at 14 days were 3.75 MPa and 3.87 MPa respectively, whereas, the 1000 °C thermoalkali-activated RM samples only at 28 days was 3.26 MPa; the above data could reach the single flexural strength (3.0 MPa) of the first-grade pavement blocks of the building materials industry standard of the People’s Republic of China-concrete pavement blocks (JC/T446-2000). The optimal preactivated temperature for different thermally activated RM was different; the optimal preactivated temperature for both thermally and thermocalcium-activated RM was 900 °C, and the flexural strength was 4.46 MPa and 4.35 MPa, respectively. However, the optimal preactivated temperature of thermoalkali activated RM at 1000 °C. The 900 °C thermally activated RM samples had better solidified effects for heavy metal elements and alkali substances. 600~800℃ thermoalkali activated RM samples had better solidified effects for heavy metal elements. Different temperatures of thermocalcium-activated RM samples showed different solidified effects on different heavy metal elements, which may be due to the influence of thermocalcium activation temperature on the structural changes of the hydration products of the cementitious samples. In this study, three thermal RM activation methods were proposed, and the co-hydration mechanism and environmental risk study of different thermally activated RM and SS were further elucidated. This not only provides an effective method for the pretreatment and safe utilization of RM, but also facilitates the synergistic resource treatment of solid waste and further promotes the research process of replacing part of traditional cement with solid waste.
The driving factors of corporate carbon emissions: an application of the LASSO model with survey data
Authors: Xia Mengyao , Cai Helen Huifen 
Published: March 2023

AbstractCorporate carbon performance is a key driver of achieving corporate sustainability. The identification of factors that influence corporate carbon emissions is fundamental to promoting carbon performance. Based on the carbon disclosure project (CDP) database, we integrate the least absolute shrinkage and selection operator (LASSO) regression model and the fixed effects model to identify the determinants of carbon emissions. Furthermore, we rank determining factors according to their importance. We find that Capx enters the models under all carbon contexts. For Scope 1 and Scope 2, financial-level factors play a greater role. For Scope 3, corporate internal incentive policies and emission reduction behaviors are important. Different from absolute carbon emissions, for relative carbon emissions, the financial-level factors’ debt-paying ability is a vital reference indicator for the impact of corporate carbon emissions.
Swimming behaviour as an alternative endpoint to assess differences in abiotic stress sensitivities between strains of Brachionus koreanus (Rotifera: Monogononta)
Authors: Granada Luana , Lemos Marco F. L. , Bossier Peter , Novais Sara C. 
Published: March 2023

AbstractBrachionus plicatilis is a cosmopolitan rotifer used as a model organism in several research areas and as live food in aquaculture. Being a species complex, responses to stressors vary even among strains of the same species and, thus, the responses of one species are not representative of the whole complex. This study aimed to address the effects of extreme salinity ranges, and different concentrations of hydrogen peroxide, copper, cadmium, and chloramphenicol, in two strains of B. koreanus (MRS10 and IBA3) from B. plicatilis species complex, by assessing effects on their survival and swimming capacity. Neonates (0–4 h old) were exposed to the stressors in 48 well-microplates, for 24 and 6 h, to evaluate lethal and behavioural effects, respectively. Tested conditions of chloramphenicol did not show any effects on rotifers. The behavioural endpoint showed to be particularly sensitive to assess the effects of high salinity, hydrogen peroxide, and copper sulfate, as swimming capacity impairment was observed for both strains in the lowest concentrations used in lethal tests. Overall, results showed that IBA3 was more tolerant to the majority of stressors, comparing to MRS10, which may be due to differences in physiological characteristics, highlighting the importance of performing multiclonal experiments. Also, swimming capacity inhibition proved to be a good alternative to the classical lethality tests, being sensitive to lower concentrations and with shorter exposure periods.
Keeping Promises to Supererogate
Authors: Robinson Michael 
Published: March 2023

AbstractPromises to perform supererogatory actions present an interesting puzzle. On the one hand, this seems like a promise that one should be able to keep simply by performing some good deed or other. On the other hand, the only way to keep it is to do something that exceeds one’s duties. But any good deed that one performs, which might otherwise have been supererogatory, will not go above and beyond what one is morally required to do in such a case because one has an obligation that one does not normally have—namely, an obligation to do something supererogatory. Thus, some scholars have argued that promises of this sort cannot possibly be kept and so are wrong to make. I show that, far from being impossible, keeping promises to supererogate is easy, and so there is nothing wrong with making promises of this sort.
The temporal dynamics of online problem-based learning: Why and when sequence matters
Authors: Saqr Mohammed , López-Pernas Sonsoles 
Published: March 2023

AbstractEarly research on online PBL explored student satisfaction, effectiveness, and design. The temporal aspect of online PBL has rarely been addressed. Thus, a gap exists in our knowledge regarding how online PBL unfolds: when and for how long a group engages in collaborative discussions. Similarly, little is known about whether and what sequence of interactions could predict higher achievement. This study aims to bridge such a gap by implementing the latest advances in temporal learning analytics to analyze the sequential and temporal aspects of online PBL across a large sample (n = 204 students) of qualitatively coded interactions (8,009 interactions). We analyzed interactions at the group level to understand the group dynamics across whole problem discussions, and at the student level to understand the students’ contribution dynamics across different episodes. We followed such analyses by examining the association of interaction types and the sequences thereof with students’ performance using multilevel linear regression models. The analysis of the interactions reflected that the scripted PBL process is followed a logical sequence, yet often lacked enough depth. When cognitive interactions (e.g., arguments, questions, and evaluations) occurred, they kindled high cognitive interactions, when low cognitive and social interactions dominated, they kindled low cognitive interactions. The order and sequence of interactions were more predictive of performance, and with a higher explanatory power as compared to frequencies. Starting or initiating interactions (even with low cognitive content) showed the highest association with performance, pointing to the importance of initiative and sequencing.
Titanium Nitride Plasmonic Nanohole Arrays for CMOS-Compatible Integrated Refractive Index Sensing: Influence of Layer Thickness on Optical Properties
Authors: Reiter Sebastian , Han Weijia , Mai Christian , Spirito Davide , Jose Josmy , Zöllner Marvin , Fursenko Oksana , Schubert Markus Andreas , Stemmler Ivo , Wenger Christian , Fischer Inga Anita 
Published: March 2023

AbstractThe combination of nanohole arrays with photodetectors can be a strategy for the large-scale fabrication of miniaturized and cost-effective refractive index sensors on the Si platform. However, complementary metal–oxide–semiconductor (CMOS) fabrication processes place restrictions in particular on the material that can be used for the fabrication of the structures. Here, we focus on using the CMOS compatible transition metal nitride Titanium Nitride (TiN) for the fabrication of nanohole arrays (NHAs). We investigate the optical properties of TiN NHAs with different TiN thicknesses (50 nm, 100 nm, and 150 nm) fabricated using high-precision industrial processes for possible applications in integrated, plasmonic refractive index sensors. Reflectance measurements show pronounced Fano-shaped resonances, with resonance wavelengths between 950 and 1200 nm, that can be attributed to extraordinary optical transmission (EOT) through the NHAs. Using the measured material permittivity as an input, the measured spectra are reproduced by simulations with a large degree of accuracy: Simulated and measured resonance wavelengths deviate by less than 10 nm, with an average deviation of 4 nm observed at incidence angles of 30° and 40°. Our experimental results demonstrate that an increase in the thickness of the TiN layer from 50 to 150 nm leads to a sensitivity increase from 614.5 nm/RIU to 765.4 nm/RIU, which we attribute to a stronger coupling between individual LSPRs at the hole edges with spatially extended SPPs. Our results can be used to increase the performance of TiN NHAs for applications in on-chip plasmonic refractive index sensors.
CIDP: Analysis of Immunomarkers During COVID-19 mRNA-Vaccination and IVIg-Immunomodulation: An Exploratory Study
Authors: Svačina Martin K. R. , Meißner Anika , Schweitzer Finja , Sprenger-Svačina Alina , Klein Ines , Wüstenberg Hauke , Kohle Felix , Walter Helene L. , Schroeter Michael , Lehmann Helmar C. 
Published: March 2023

Abstract
Availability of COVID-19 mRNA vaccine for patients with chronic inflammatory demyelinating polyneuropathy (CIDP) treated with intravenous immunoglobulin (IVIg) raises the question of whether COVID-19 mRNA vaccine influences disease activity or IVIg-mediated immunomodulation in CIDP. In this exploratory study, blood samples of CIDP patients on IVIg treatment were longitudinally analyzed before and after vaccination with a COVID-19 mRNA vaccine. A total of 44 samples of eleven patients were characterized at four timepoints by ELISA and flow cytometry in terms of immunomarkers for disease activity and IVIg-immunomodulation. Apart from a significantly lower expression of CD32b on naïve B cells after vaccination, no significant alteration of immunomarkers for CIDP or IVIg-mediated immunomodulation was observed. Our exploratory study suggests that COVID-19 mRNA vaccine does not have a relevant impact on immune activity in CIDP. In addition, immunomodulatory effects of IVIg in CIDP are not altered by COVID-19 mRNA vaccine. This study was registered in the German clinical trial register (DRKS00025759).
Graphical Abstract
Overview over the study design. Blood samples of CIDP patients on recurrent IVIg treatment and vaccination with a COVID-19 mRNA vaccine were obtained at four timepoints for cytokine ELISA and flow cytometry, to assess key cytokines and cellular immunomarkers for disease activity and IVIg-immunomodulation in CIDP.
Die Versprechungen „neuer Arbeit“ – eine kritische Betrachtung
Authors: Zirkler Michael 
Published: March 2023

ZusammenfassungMit dem Begriff der „neuen Arbeit“ gehen Versprechungen einher, welche kritisch beleuchtet werden sollen. „Neue Arbeit“ kann nur vor dem Hintergrund des bestehenden Zeitgeistes verstanden werden; dieser bemüht das Narrativ des selbstbestimmten und eigenverantwortlichen Arbeitssubjekts, das weniger an ökonomischen Transaktionen als vielmehr an Sinn interessiert ist. Die zentralen Versprechungen werden dargestellt und ihre Bruchlinien skizziert. Dabei wird deutlich, dass „neue Arbeit“ nicht (nur) als Emanzipation und Befreiung gesehen werden kann, sondern als Notwendigkeit spätkapitalistischer Anforderungen an Komplexitäten, die nicht (mehr) anders zu bewältigen sind.