bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychiatric Morbidity in Women With Previous Gestational Diabetes Mellitus: A Nationwide Register-Based Cohort Study
Authors: Christensen Maria Hornstrup , Andersen Marianne Skovsager , Rubin Katrine Hass , Nohr Ellen Aagaard , Aalders Jori , Vinter Christina Anne , Jensen Dorte Moeller 
Published: March 2023

OBJECTIVE
To investigate associations between previous gestational diabetes mellitus (GDM) and incident psychiatric morbidity, and to explore the role of subsequent diabetes development in psychiatric morbidity risk.

RESEARCH DESIGN AND METHODS
A nationwide register-based cohort study including all women delivering in Denmark from 1997 to 2018 was conducted. GDM exposure was based on diagnosis code, whereas psychiatric morbidity outcome was based on diagnosis code and psychopharmacological medication use. Multiple Cox regression and mediation analyses were performed.

RESULTS
In a study population of 660,017 women, previous GDM was associated with increased risk of depression based on diagnosis code and/or medication use (adjusted hazard ratio [aHR] 1.22 [95% CI 1.18–1.27]), any psychiatric diagnosis (aHR 1.20 [95% CI 1.13–1.27]), and any psychopharmacological medication use (aHR 1.21 [95% CI 1.17–1.25]). Moreover, risk of depressive and anxiety disorders, as well as antidepressant and antipsychotic medication use, was increased, with aHRs ranging from 1.14 (95% CI 1.05–1.25) to 1.32 (95% CI 1.22–1.42). No associations were found regarding substance use disorders, psychotic disorders, bipolar disorders, postpartum psychiatric disease, or anxiolytic medication use. Psychiatric morbidity risk was higher in women with versus without subsequent diabetes development. However, GDM history affected risk estimates only in women without subsequent diabetes. Subsequent diabetes mediated 35–42% of the associations between GDM and psychiatric morbidity.

CONCLUSIONS
GDM was associated with increased psychiatric morbidity risk. Subsequent diabetes development played a significant role in future psychiatric morbidity risk after GDM, although it only partly explained the association.
The Impact of African Swine Fever (ASF) on Romanian Pig Meat Production: A Review
Authors: Ladoşi Ioan , Păpuc Tudor A. , Ladoşi Daniela 
Published: March 2023

Abstract
The first outbreak of African Swine Fever (ASF) in Romania was recorded in a backyard holding in Satu Mare County in July 2017 as a result of a previous large-scale spread of the virus in wild boars and domestic pig populations in two of Romania’s neighbouring countries, Ukraine and the Republic of Moldova. Since then, more than 1.3 million domestic pigs have been infected in more than 5600 backyard holdings and commercial farms all over Romania where stamping out procedures have been performed afterwards. The spread of the disease could not be contained despite the contingency plans developed by the authorities based on the current EU and Romanian legislation, and currently, the entire territory of Romania is considered to be affected, leading to a significant decline of the pig inventory and major damages in the commercial farming system. Consequently, the amounts of pork imported from other EU member states have increased yearly, pig meat becoming the main commodity on the list of agricultural goods purchased by Romania. 2021 has been by far the worst year for Romanian pig meat production, generating the highest financial losses mainly due to the inability of authorities and policymakers to implement effective and efficient disease control measures.
Design of a Replicative-Competent MGF110 (1L-5-6L) Deleted African Swine Fever Virus (Genotype II)
Authors: Nefedeva Mariia V. , Malogolovkin Alexander S. , Titov Ilya A. 
Published: March 2023

Abstract
Viral individual genes functions and their role in the interaction with the host cells remain the main area in the study of African swine fever virus (ASFV) biology. The extreme heterogeneity of the ASFV makes it difficult to develop vaccines against this pathogen. In this work, we generated the ASFV deletion mutant virus Volgograd/D(1L-5-6L) with the six genes deletion in multigenic family 110 (MGF110) (1L-5-6L) and studied its characteristics in vitro. The homologous recombination method was used for the deletion in ASFV parental strain Volgograd/14с. A series of six passages was carried out in the COS-1 cell culture using the limiting dilution method. The recombinant strain Volgograd/D(1L-5-6L) MGF110 was selected by the plaque formation method. Performed study of viral replication showed no changes in viral growth kinetics in comparison with the parental strain. The ASFV Volgograd/D(1L-5-6L) MGF110 is a great tool available to test the importance of MGF110 for virus virulence and vaccine development.
Preventive Supplementation of Vitamin E and Selenium as a Factor in Improving the Success Rate of Embryo Transfer in Cattle
Authors: Šmigoc Jernej , Pavšič Vrtač Katarina , Jakovac Strajn Breda , Stvarnik Mateja , Mrkun Janko 
Published: March 2023

Abstract
The effects of stress on processes in the body are becoming an increasingly relevant research subject. The reproductive ability of bovine animals largely depends on these effects, whilst embryo transfer is increasingly being used as a reproduction method. In this study, we established the differences in the implantation ability of heifers that were treated (N=17) with selenium (Se) and vitamins AD3E, and non-treated heifers. Upon transfer, we took blood samples from both groups and used the total antioxidant status (TAS) value to analyze the presence of reactive oxygen species (ROS), the levels of non-esterified fatty acids (NEFA) and the levels of vitamin E and Se in blood plasma. In the study, we were able to demonstrate that preventive measures in the form of supplementation of vitamin E and Se, mitigate the effects of oxidative stress, strengthen the ability of an organism to improve the dynamic relationship between free radicals and antioxidants, improve the energy status of cattle, positively impact reproductive parameters and increase the success rate of embryo transfer. The difference in the number of successful embryo implantations between the control and treated group was statistically significant, with 64.7% of treated heifers being pregnant after embryo transfer and giving birth to healthy calves. In the control group, the implantation success rate was 41.2%. The supplementation of antioxidants in the form of a combination of vitamin AD3E and Se, proved to be a good method for strengthening the defense of an organism and an effective mean of preventive clinical approach for improving fertility parameters.
Orthovoltage X-Ray Therapy of Large Cell Invasive Nasal Lymphoma in Cat
Authors: Rogachev Alexander , Gazin Alexey , Zuenkova Yuliia 
Published: March 2023

Abstract
Feline nasal lymphoma is generally a localized radiosensitive tumor. Treatment options include radiation therapy, chemotherapy, or a combination of both modalities. Radiation therapy (RT) in a combination with chemotherapy lead to median survival from 19 months to 955 days. The objective of this paper is to report a case of a large cell late stage invasive feline nasal lymphoma and to evaluate the results of orthovoltage radiation therapy and its side effects. A 12-year-old female mixed breed cat was presented with nasal discharge, sneezing and hyporexia. Definitive histopathology diagnosis was diffuse large cell lymphoma. Computed tomography revealed an advanced stage of the disease, an intranasal mass, bone lysis, invasion of the orbital space and central nervous system. A radical course of X-ray therapy was performed (SFD = 4 Gy, TSD = 40 Gy, 10 sessions, 3 times a week). Radiation side effects were well tolerated and resolved with supportive treatment. Lymphoma is a systemic process and requires a multidisciplinary approach. On most cases, the penetrating ability of radiation therapy of 3.5 cm in depth is enough for small domestic animals. A significant effect is noted in the middle of the treatment course. The fractionated regime did not cause early radiation damage. The relapse-free period was up to 8 months. The patient had a satisfying quality of life for 5 months. Orthovoltage X-ray therapy can be considered as a treatment choice for local nasal lymphoma. X-ray therapy is a widely used modality in veterinary medicine considering the price of machines and costs of treatment.
Use of Zinc Nanoparticles and/or Prodigiosin to Mitigate Heat Stress in Rabbits
Authors: Aldal’in Hammad K. , Al-Otaibi Aljohara M. , Alaryani Fatima S. , Alsharif Ifat , Alghamdi Youssef S. , Abd El-Hack Mohamed E. , Abdelnour Sameh A. 
Published: March 2023

Abstract
Heat stress (HS) is an environmental challenge affecting animals’ health, productivity and welfare. This work aimed to inspect the protective effect of zinc oxide nanoparticles (ZnNPs) and/or prodigiosin (PRG) against inflammation, immune dysfunction, oxidative stress and endoplasmic reticulum (ER) stress triggered by HS in growing rabbits. Growing weaned rabbits (one hundred males, 35 days of age) were randomly assigned into four groups. The first group was fed a basal diet without supplementation and the 2nd, 3rd, and 4th groups were fed diets containing zinc oxide nanoparticles (ZnNPs, 50 mg/kg diet), prodigiosin (PRG, 100 mg/kg diet) or their mixture (ZnPRG) under HS conditions for eight successive weeks. The dietary inclusion with ZnNPs and/or PRG significantly boosted FBW (final body weight), CBWG (cumulative body weight gain), and FCR (feed conversion ratio) and had no substantial impacts on the CFI (cumulative feed intake) as compared with those in HS one. All supplemented treatments significantly unveiled an increase in the values of RBCs, hemoglobin, and platelets and significant decreases in WBCs, basophils and monocytes with non-statistical effects on hematocrit, MCV, MCHC, neutrophils and eosinophils. Compared with the HS group, all supplemental groups showed a significant reduction in TNFα, IL4, IFN-γ, TLR-4 and amyloid A levels and DNA damage markers (OHdG) and significant increases in the levels of NO and lysosome activity. Rabbits in the ZnPRG group had significantly higher IgG and IgM levels compared to other groups. The highest value of CAT and GSH levels were found in rabbits that received the mixture of ZnNPs (50 mg) and prg (100 mg) in their diets under elevated temperatures. Additionally, both treatments, PRG and ZnNPS, significantly (P<0.001) reduced the values of MDA and MYO, while all treated groups had significantly reduced PC contents compared with the HS group. Co-supplement with ZnPRG showed a considerable restoration in the higher immune expression of reticulum oxidative stress such as GRP78 and IRE1 in hepatic tissues induced by hs conditions. The mixture of ZnNPS and prg presented more robust effects in mitigating the adverse impacts of hs in rabbits compared with the individual treatments. Collectively, ZnNps and/or PRG alleviated oxidative stress and dna damage. In addition, it enhanced the antioxidant capacity and immune function, and downregulated ER stress such as GRP78 and IRE1 signaling in the hepatic tissues of stressed rabbits.
Wissenschaftliche Grundlagen zum Strategiediskurs für einen nachhaltigen Pflanzenbau
Authors: Feike Til , Frei Michael , Germeier Christoph , Herrmann Antje , Hülsbergen Kurt-Jürgen , Kaul Hans-Peter , Komainda Martin , Kottmann Lorenz , Möller Kurt , Nendel Claas , Pasda Gregor , Pekrun Carola , Seidel Sabine , Stützel Hartmut , Wrage-Mönnig Nicole 
Published: March 2023

Summary
Scientific facts about the relationships between the goals are indispensable for the rational social discourse on solving the various conflicting goals on the way to sustainable crop production. Therefore, the German Society for Agronomy has compiled scientific findings on the topics of biodiversity, climate relevance and climate resilience, nutrient management, crop protection, soil protection and production of renewable raw materials, and identified the existing need for research. After an executive summary that highlights the findings, the subject areas are explained in detail. The purpose of this paper is not to make recommendations for policy-making, but to support the public debate by providing factual information.
Exchanged communities of abomasal nematodes in cervids with a first report on Mazamastrongylus dagestanica in red deer
Authors: Pyziel-Serafin Anna Maria , Vetter Wiktoria , Klich Daniel , Anusz Krzysztof 
Published: March 2023

Abstract

Introduction
Among large wild game in Poland, the most numerous cervids are red deer and roe deer. Although these species live free, they should be under veterinary supervision because they can transmit infectious agents and parasites to livestock. The aim of this study was to evaluate the biodiversity of the abomasal nematodes which parasitise cervids and present the visual and dimensional characteristics of their spicules.

Material and Methods
Overall, 2,067 spicules of nematodes derived from nine red deer and five roe deer were measured and microphotographed in order to determine the species. The predominant Spiculopteragia boehmi was additionally confirmed molecularly by PCR. The spicule lengths of the most common species found in both hosts simultaneously were compared.

Results
Fourteen species of abomasal nematode were identified. All examined animals but one were infected. The most prevalent parasites in both host species were S. boehmi and Ostertagia leptospicularis. The alien Ashworthius sidemi was found in both hosts, whereas Haemonchus contortus was identified only in red deer. Mazamastrongylus dagestanica was noted in red deer for the first time. A 262-base-pair nucleotide sequence of S. boehmi was obtained and deposited in GenBank. Significantly longer spicules were found in red deer-derived O. leptospicularis and S. boehmi and shorter structures were seen in A. sidemi.

Conclusion
The widespread exchange of abomasal nematodes between various ruminant species questions the relevance of their division into specialists and generalists.
Equidad en el trato a los pacientes. Parte 2.
Authors: Maya Mejia Jose Maria 
Published: March 2023

Un médico especialista, además de su vinculación de medio tiempo con una institución de prestación de servicios, tiene un consultorio médico en un centro de especialistas de la ciudad. El médico instruye a su secretaria para que establezca una priorización en la asignación de las citas de acuerdo con el tipo de vinculación a la seguridad social y planes complementarios o pólizas que el paciente posea. En esta priorización se privilegia a los pacientes de más altos ingresos y mejor capacidad de pago por la atención.Un paciente de profesión obrero y perteneciente al régimen contributivo de salud (POS contributivo) se queja de la inoportunidad de las citas e incluso de la imposibilidad de obtenerlas cuando le informa a la secretaria cuál será su forma de pago de la consulta y el régimen al que pertenece. El médico responde por escrito al reclamo que le hace el paciente, aduciendo que él tiene un ejercicio liberal de su profesión y, por ende, puede poner las condiciones en que este servicio se presta en el consultorio particular de su propiedad.Se analiza el caso desde la perspectiva de los principios de la bioética y en especial del principio de justicia.
ANALISIS VARIABEL PENGEMBANGAN PELABUHAN LAUT (PELABUHAN PENUMPANG) SEBAGAI BANDAR UDARA PERAIRAN UNTUK OPERASIONAL PESAWAT APUNG (SEAPLANE) DI INDONESIA
Authors: Aditiya Revo Rizki , Triadmojo Bambang , Suparma Latif Budi 
Published: March 2023

The operation of water aerodrome for seaplane operations in Indonesia is regulated within the scope of the minimum operational specifications of water aerodromes for serving seaplane with a maximum limit of 30 seats. The regulation provides only for planning in the air side and aviation safety, while in practice it also deals with the planning and development of sea or maritime transport on port, security and safety at the sea. The purpose of this study is to identify variables for the development of port (passenger port) so that they can be used as water airports for seaplane operations with security and safety aspects of shipping and aviation activities. The research was conducted using a qualitative method with a descriptive approach through observation regulation documents and semistructure interviews to 10 speakers from the Ministry of Transportation Indonesia, water airport operators, and community leaders. Based on the analysis of data, this research produces important variables in the development of port (passenger port) as water aerodrome for seaplane operations in Indonesia, (1) need for specific laws and regulations, (2) need for a water airport authority, (3) the purpose of development by considering the categorization of shipping or maritime and aviation aspects.
Materials for the flora of Uzhgorod city based on herbarium analysis Uzhhorod National University
Authors:   State Higher Educational Institution «Uzhhorod National University», Soyma M. 
Published: March 2023

The herbarium collection of the Uzhhorod National University (Herbarium UU), both the main collection of the flora of Transcarpathia, and the doublet collections of A. Margittai and L. Wagner are very interesting in the regional sense and have both scientific and historical and cultural significance. The herbarium of the Department of Botany of the Uzhhorod National University (UU) was established in 1947. Today, it is stored in the Botanical Garden and has about 107,000 herbarium specimens [4]. The personal collections of L. Wagner and A. Margittai are stored separately. The herbarium collection of the Uzhgorod National University covers mainly the territory of the Ukrainian Carpathians and the Prytisyan lowland and is currently the most complete herbarium collection of the flora of Transcarpathia. In particular, specimens of many species of aboriginal flora are kept in the herbarium, and the collection of regional exotics is particularly interesting. As a result of the analysis of the herbarium materials of the Department of Botany of the Uzhhorod National University, it was established that 469 species were recorded from the territory of the city of Uzhhorod. By the number of species, the families Brassicaceae, Asteraceae, Rosaceae, Fabaceae and Lamiaceae are the most numerous, Caryophyllaceae, Poaceae and Boraginaceae are much smaller. During the audit of the major part of the scientific herbarium of the Botany Department of UzhNU (flora of Transcarpathia), from all the herbarium specimens, those that were collected in the territory of the city of Uzhhorod or its surroundings, which are now included in the administrative boundaries of the city (for example, the villages of Domanyntsi, Dravtsi, Horyany, Radvanka, Radvansky forest, etc.) were selected. Among the found herbarium specimens are species that are now considered highly invasive within Ukraine. It is likely that for some of them the data refer to the first or one of the early findings of wildness (Amorpha fruticosa L., Robinia pseudoacacia L., Acer negundo L., etc.)
INTRODUCTION OF COMBAT SAMBO ARSENAL INTO THE HAND-TO-HAND TRAINING SYSTEM OF FUTURE OFFICERS OF THE NATIONAL GUARD OF UKRAINE
Authors: Khatsaiuk О. V. , Turchynov A. V. , Kontarovskyi R. V. , Volianskii V. G. , Moskalenko Yu. V. , Nesterchuk D. A. 
Published: March 2023

Despite the significant number of works in the specified direction of scientific intelligence, the issue of expanding the arsenal of service-applied hand-to-hand combat (with an accented use of technical and tactical combat sambo combinations) future officers of institutions of the security and defense sector of Ukraine – an insufficient number of scientific works is devoted to it, which emphasizes the relevance of the chosen direction of scientific research.
The main goal of the study is the development and testing of pedagogical conditions for the formation of the readiness of future officers of the National Guard of Ukraine (NGU) to engage in hand-to-hand combat with the enemy in various conditions of service-combat activities with an emphasis on the use of combat sambo arsenal. During the empirical research, the following methods were used: axiomatic, idealization, historical and logical, descent from the concrete, mathematical and statistical formalization (criterion χ2).
Based on the results of the conducted empirical research, the organizational and pedagogical conditions for the formation of the readiness of future officers of the National Guard of Ukraine to engage in hand-to-hand combat with the enemy in various conditions of service and combat activity were developed and tested (with an accented use of the combat sambo arsenal). The above-mentioned organizational and pedagogical conditions are implemented during 3 main blocks: organizational and diagnostic, corrective and constant. Summarizing the results obtained during the pedagogical experiment, it was established that all the conditions for conducting an empirical study were met. The experimental work had a positive effect on increasing the level of physical and special physical fitness of future NGU officers, which contributed to the increase in the efficiency of their performance of assigned tasks. It is noted that these changes occurred to a greater extent in Eg cadets compared to Kg, and these changes are statistically reliable.
Prospects for further research in the chosen direction of scientific intelligence provide for the improvement of the system of sectional work of future officers of the National Guard of Ukraine from service-applied martial arts.
Take part in the process of forming a healthy system informative environment
Authors: Kabatska O. V. , Kuidina T. М. , Babych L. M. , Malkova J. P. 
Published: March 2023

The article examines the role and place of health-saving technologies in the system of modern education, where an important role is assigned to the interaction of teachers, psychologists, workers in social spheres, the need to review the accumulated experience and develop new approaches taking into account the changed living conditions, namely: military status substantiated in Ukraine; transition to online education; strengthening of the information flow; humanity's dependence on the Internet; psychophysiological stress, hypodynamia, etc.
A historical-pedagogical review has been conducted, which introduces the developments in the issues of preserving and strengthening the health of students, taking into account their age and social characteristics, which allows relying on the foundations of pedagogical culture when setting and solving the tasks of forming a health culture, introducing health into pedagogical practice of energy-saving technologies, as an important direction for preserving and strengthening the health of children and adolescents in modern conditions.
Researches, made by the scientists, had shown that the urgent task of the development of the national education system was to create consistency between modern social requirements for the health of the young generation and pedagogical conditions for the formation of motivational and value attitudes of students towards their own health and life.
The article also examines the essence of health-saving technologies, the conditions for their implementation, and the approaches of modern domestic and foreign authors to the issues of leading a healthy lifestyle for student youth. In their scientific works, scientists express comments on the preparation of graduates of pedagogical universities to implement the socially important task of raising a healthy generation based on the organization of a health-preserving educational process.
Thus, it is necessary to introduce pedagogical conditions into the work of higher education institutions in order to implement educational programs that meet the requirements of preserving and strengthening the physical, mental, and social components of the health of the young generation and raising a healthy personality capable of adapting to the complex conditions of modern life.