bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFICACY OF ALPHA-ADRENERGIC RECEPTOR ANTAGONISTS IN THE TREATMENT OF DISTAL URETERIC STONES: A PAEDIATRIC STUDY
Authors: Brohi Illahi Bux , Bhatti Muhammad Shahid , Siyal Roshan Ali , Ali Farhan , Kaimkhani Zulfiqar , Laghari Hamid Raza 
Published: December 2022

Background: European association of urology (EAU) recommended α- blockers for managing distal ureteric stones in the paediatric population. This paper will help to understand the efficacy of Silodosin as a medical expulsive agent for distal ureteric stones in children, along with the required time duration of stone expulsion. Methods: Forty participants were enrolled and evaluated for complaints, pain severity, associated symptoms, and ultrasound was done to confirm the position and size of the distal stone. Follow-ups were scheduled after every 7 days (1 week) for redo ultrasound and assessment of the stone position. Data was entered and analyzed in the SPSS version 23. To evaluate the significance of data chi-square test was performed, p-value <0.005 was considered significant. Results: The minimum and maximum age limits recorded are 3 years and 18 years respectively with a mean age of 9.5±4.5 years and mean stone size was measured as 0.6±0.1 cm. Distribution of stone size indicated the minimum size of 0.4 cm and maximum of 1.0 cm stone in study subjects. Maximum stone expulsion was reported within 14 days or an initial 2 follow-up scans. Conclusion: The efficacy of Silodosin and medical expulsive therapy evaluated the effect on pain management as pain episodes declined with Silodosin treatment and spontaneous passage of stones were increased within the first 14 days of treatment. This study will be a beneficial contribution in literature especially in a developing country population where paediatric urolithiasis is on expansion and ongoing
TRANSLATION, CROSS-CULTURAL ADAPTATION AND VALIDATION OF POLYCYSTIC OVARIAN SYNDROME QUALITY OF LIFE SCALE IN PASHTO
Authors: Mahjabina S Ghayur  , Kareem Rabia , Wahab Samdana , Inayat Sumaira , Karim Rukhsana , Rauf Sethi Mifrah , Nasr Malik Naila , Irfan Muhammad 
Published: December 2022

Background: Cross-cultural adaptation and validation are important for the reliable use of a scale. This study was conducted to translate and validate the polycystic ovarian syndrome quality of life scale (PCOSQOL) in Pashto. Methods: This study was conducted in tertiary care teaching hospitals of Peshawar from August to December 2021 on 333 patients diagnosed with polycystic ovarian syndrome. Using forward-backward method, three bilingual experts translated PCOSQOL from English to Pashto. The exploratory and confirmatory factor analyses, Cronbach alpha reliability and construct validity of PCOSQOL (Pashto version) was found out using SPSS version 25 and AMOS version 26 for data analysis. Results: The mean age of the sample was 25.73±5.89 years. Majority were married (n=260, 78.1%), uneducated (n=180, 54.1%) and unemployed (n=303, 91%). Factorial validity of the Pashto version showed it to be a five-factor model. Regarding construct validity, the factor loading through Item total correlation scores revealed highly satisfactory correlation coefficients. The Cronbach's alpha reliability of the Pashto version of PCOSQOL was 0.918. The confirmatory factor analysis (CFA) indicated a good fit model with a CFI of 0.91 and a RMSEA value of .08. Poor quality of life (89.98±28.5) was reported in 169 (50.8%) women and this was irrespective of their educational and occupational background (p>0.05) respectively. Pearson coefficient correlation test showed a significantly positive Inter-scale correlation (p<0.05). Conclusion: Pashto version of PCOSQOL is a reliable instrument to measure the quality of life in patients with polycystic ovarian syndrome and can be used in Pashto speaking patients.
TRACHEO-CUTANEOUS FISTULA: A RARE PRESENTATION DUE TO A FORGOTTEN RUBBER BAND IN NECK OF A YOUNG GIRL
Authors: Amna Ikram  , Idrees Amna , Somia Ilyas  , Sikandar Ali  , Muhammad Ali Shiekh  
Published: December 2022

The presence of foreign bodies in a chronic wound is a well-known phenomenon. The common locations are wrist, neck and chest cavity. Retained foreign bodies in soft tissues become reason for formation of sinus which can be superimposed by infection. Most of foreign bodies in soft tissues remain un-detected, becoming the reason for delayed diagnosis. Some of the foreign bodies are inert and stay in the body tissues for prolonged time without causing any deleterious effect but few of them erode into surrounding tissues and cause prolonged illness. Tracheo-cutaneous fistula secondary to a foreign body in a child is rarely reported. In this case, the patient had retained foreign body in her neck for almost eight years which remained un-diagnosed while being treated for various diseases.
Transgender achter de deur
Authors: Jacobs P. (Pauline) 
Published: December 2022

Transgender achter de deur. Een onderzoek naar en aanbevelingen voor de behandeling van transgender gedetineerden.
De laatste jaren neemt de steun voor het klassieke idee dat geslacht binair is af en is er meer maatschappelijke en politieke aandacht voor transgender personen. In het gevangeniswezen wordt echter nog steeds uitgegaan van binaire geslachten. Transgender gedetineerden zijn kwetsbaar voor mensenrechtenschendingen, onder andere vanwege een verhoogd risico op discriminatie, intimidatie en misbruik. In dit artikel wordt stilgestaan bij recente onderzoeksbevindingen ten aanzien van de grootte van de groep transgender gedetineerden in Nederland, de plaatsing van transgender gedetineerden, de bejegening door medegedetineerden en personeel en de mogelijkheden voor medische zorg in de inrichting.
Het vaststellen van causaal verband als bewijsbeslissing: een pleidooi voor causaal realisme
Authors: Rozemond N. (Klaas) 
Published: December 2022

Het vaststellen van causaal verband als bewijsbeslissing: een pleidooi voor causaal realisme
De heersende opvatting in de rechtspraak en de literatuur over causaliteit is dat het causale verband tusssen een gedraging en een gevolg moet worden vastgesteld aan de hand van de leer van de redeliijke toerekening. Die leer heeft in de rechtspraak echter slechts een beperkte rol bij het verwerpen van bepaalde bewijsverweren. In de meeste gevallen uit de rechtspraktijk wordt het causale verband vastgesteld aan de hand van empirisiche ervaringsregels en specialistische deskundigenverklaringen waarin de leer van de redelijke toerekening geen rol speelt.
Aproximación a la desautomatización de los pragmatemas en Twitter
Authors: Ovejas Martín Vanesa 
Published: December 2022

Los pragmatemas son enunciados fraseológicos restringidos por la situación extralingüística de uso. ¿De cuánto estás?, Buenos días, Hablando del rey de Roma, por la puerta asoma o Recién pintado son ejemplos de ellos. Puesto que son unidades convencionalizadas, pueden desautomatizarse, esto es, están sometidas a la modificación intencionada y creativa de los hablantes.
En este trabajo estudiamos la desautomatización de los pragmatemas en la red social Twitter. En el análisis de los datos tenemos en cuenta la intención comunicativa con la que los usuarios emplean este fenómeno, los niveles lingüísticos modificados y los recursos utilizados por los hablantes. Para ello, trabajamos con una base de datos de elaboración propia que consta de 155 pragmatemas y un corpus constituido por 165 tuits.
El análisis cualitativo de los datos sugiere que la intención comunicativa más buscada con este fenómeno es la producción de un efecto cómico, si bien, en ocasiones, ello constituye un medio para otros propósitos, como expresar una crítica o persuadir a los interlocutores de comprar un producto. Asimismo, los ejemplos analizados reflejan que existen diferentes tipos de desautomatización, en función del nivel lingüístico afectado: i) el formal, si se sustituyen o se añaden nuevos elementos al pragmatema original; ii) el semántico, si se altera el significado por mecanismos como la metáfora, la ironía o la polisemia; iii) el pragmático-discursivo, si se modifican uno o varios de los elementos lingüísticos que restringen al pragmatema.
As meias verdades da reforma do ensino médio
Authors: De Oliveira Ramon 
Published: December 2022

As justificativas apresentadas para a reforma do Ensino Médio ancoram-se em meias verdades sobre a insatisfação dos jovens em relação à qualidade e ao sentido desse nível da educação básica para suas vidas. Este artigo, a partir de documentação referente à reforma e de literatura pertinente, analisa essas justificativas e demonstra que suas intencionalidades definem as respostas e as conclusões às quais a sociedade deve chegar. Tais justificativas são destituídas, de forma intencional, de análises científicas especializadas sobre a materialização efetiva dessa última etapa da educação básica. Para consolidar a retórica reformista, foi fundamental o silenciamento do pensamento divergente e o apoio da mídia. Os reformadores não quiseram ouvir os sujeitos que vivenciam a escola e nem escutar o que os jovens desejam de suas escolas ou os professores sobre as suas condições para efetivar um Ensino Médio de qualidade e atrativo aos jovens estudantes. Sua retórica, politicamente estruturada a partir de meias verdades e do desprezo da produção acadêmica, intenciona promover sua aceitação pública, efetivando retrocessos na oferta de Ensino Médio nas escolas públicas brasileiras. A dualidade reafirma-se sob o discurso de uma nova estrutura educacional, de um novo currículo, de um novo papel que a juventude passa a ter na definição de seus projetos de vida.
The Ecology of Nationalism and the Representation of Lower Castes in the Novel Tamas
Authors: Ashutosh Manohar Popate  
Published: December 2022

The colonization of India had awful consequences on the lives of people as the nation was severely affected by problems like poverty, illiteracy, unhygienic and callous living producing, in addition to the already prevailing sociological and economic problems, environmental and conservational crisis, the root cause of which was to be found in the incessant exploitation of natural resources by the ruling European colonial powers in India. Resultantly, the Gandhian struggle for independence could not restrict itself merely to the primary objective of acquiring a politically independent statehood for India, but it had to keep on its agenda also problems of ecology, hygiene and conservation. The novel Tamas describes analogous labors made by the congress working committee volunteers in the Muslim area despite antagonism by the Muslim League workers. This ecology of nationalism, however, could not sustain long as the ecological purity of a mosque and a temple, in retaliatory action, was polluted by the perpetrators. The novel regularly, throughout the narrative, establishes a connection between the ideas of pureness and dirtiness and the consequential communal clashes in the city by showing how harmony and mutual veneration for each other’s community, the so-called ecology of nationalism and political unity, was thwarted by an error of Nathu, a member of the lower caste community. In a broad sense, the character of Nathu is presented representatively in a way to demonstrate how the act of a socially impure community was accountable for the fall of the ecology of Indian nationalism rather than the political desires and mistakes of leadership.
Voids to Cementitious Materials Ratio as a Control for Tensile Strength on CTRB with Natural Pozzolan
Authors: Waani Joice Elfrida 
Published: December 2022

Abstrak
Posolan alam diklasifikasikan sebagai material tambahan pada campuran Semen (SCMs) karena sifat sementasinya yang jika ditambahkan dalam campuran beton dan semen sebagai bahan aditif berpengaruh positif terhadap campuran. Penelitian ini bertujuan untuk mengetahui pengaruh jumlah posolan alam, tras sebagai substitusi parsial semen Portland, terhadap rasio antara porositas dan kadar material semen pada Indirect Tensile Strength (ITS) dan Resilient Modulus (MR) campuran CTRB. Campuran CTRB yang menjadi target pengujian ini mengandung komposisi Material Reclaimed Asphalt Pavement (RAP) dan Reclaimed Aggregate Materials (RAM) yang berbeda yaitu 40% RAP : 60% RAM dan 60% RAP : 40% RAM. Hasil penelitian menunjukkan bahwa dengan meningkatnya kandungan material semen (Civ*), nilai ITS meningkat seiring dengan penurunan porositas (η) untuk campuran 40% RAP dan 60% RAP CTRB dengan substitusi pozzolan alam 15% dan 30% terhadap kandungan semen 2%, 4% dan 6%. Dalam penelitian ini juga dilakukan pengujian MR terhadap kedua campuran CTRB yang sama dengan variasi derajat tekanan confining dan deviatoric pada 5000 MPa hingga 7900 MPa.
Kata-kata Kunci: CTRB, Posolan alam, material tambahan semen, porositas, MR, ITS.
Abstract
Natural pozzolan is classified as Supplemental Cementitious Materials (SCMs) as it exhibits cementitious properties which is gradually being applied in cement mixtures as additives. This research aims at exploring the effect of trass as natural pozzolan, to the porosity and cementitious ratio on Indirect Tensile Strength (ITS) and Resilient Modulus (MR) in Cement Treated Recycled Base (CTRB) pavement mixtures. CTRB mixtures containing two different proportions of Reclaimed Asphalt Pavement (RAP) and Reclaimed Aggregate Materials (RAM). Mixtures of 40% RAP : 60% RAM and 60% RAP : 40% RAM were considered as target mixtures that can be achieved in the field based on mixture properties related to ITS and MR. The laboratory investigation confirmed that with increasing of cementitious materials content (Civ*), the ITS value increases in conjunction with the decrease in porosity (η) for the 40% RAP and 60% RAP CTRB mixtures with 15% and 30% natural pozzolan substitution to the 2%, 4% and 6% cement content. In this study, MR tests were also carried out on both mixtures of the same CTRB with variations in the degree of pressure of confining and deviatoric stress at MR test from 5000 MPa to 7900 MPa..
Keywords: CTRB, natural pozzolan, supplemental cementitious materials, porosity, MR, ITS.
TRADITIONAL GAMES AS ONE OF THE ALTERNATIVE LEARNING MODELS IN SHAPING CHILDREN'S CHARACTERS
Authors: Hendrowati Tri Yuni 
Published: December 2022

This research is to find out how traditional games as one of the alternative learning models in shaping the character of children in SD Negeri 2 Sendangasih. This type of descriptive research with a qualitative approach. Instruments used include illustrated storybooks, dolls, counterfeit items, plants, drawings. And the most commonly used is to use storybook props. This research is a class action research, conducted through three cycles each cycle consisting of preparation, implementation, observation, and interview. Judging from the results of the research that has been done shows a sufficient improvement The results of the study show: (1) The process of character building in the classroom, family, and community through traditional children's games at SD Negeri 2 Sendangasih, the process of character education is carried out by balancing between moral knowing, moral feeling, and moral action. The habit of using moral knowing, moral feeling, and moral action on every decision will educate people to be human beings with character, who have clear principles and handles. (2) Character values that develop in the classroom, family, and community at SD Negeri 2 Sendangasih include values related to the creator, values related to oneself, values related to others, values related to the environment, and national values. (3) The impact of character education planting through traditional games at SD Negeri 2 Sendangasih includes children becoming more creative, socially high, confident, more harmonious with family, manners, socializing well, and the output has a positive impact.
Analisis Behavioral Intention Dan Use Behavior Terhadap Pengguna Fintech Dana Menggunakan Metode Utaut 2
Authors: Damayanti Komang Putri , Lavianto Sephy , Dwi Putri I Gst Agung Pramesti 
Published: December 2022

Fintech DANA is currently used for non-cash transactions due to the convenience and practicality of transactions offered by service providers. However, it is currently unknown to what extent the success of the electronic wallet that has been implemented and there are still problems such as loss of balance, failure to top up balances and the features of the DANA application that are still poorly understood. One of the determining factors for the success of a system that is implemented is from the side of user acceptance, namely behavioral intention (user interest) and use behavior (user behavior). The purpose of this study was to find out what factors could influence the Behavioral Intention and Use Behavior of DANA Fintech Users towards private workers in the city of Denpasar. This research was conducted using a quantitative approach, distributing online questionnaires, and analyzing data processing using SPSS version 25 and SmartPLS 3.0 software. the results of the 12 (twelve) hypotheses proposed, 7 (seven) hypotheses were declared insignificant and rejected because the T-statistical value of the hypothesis was less than 1.96, while 5 (five) hypotheses were declared significant and accepted because the T-statistical value of the hypothesis is more than 1.96. The results of this study are expected to be one of the considerations in making decisions for electronic wallet service providers to be implemented more optimally.
Relationship between Sanitation Facilities and Mother's Behavior Against Stunting in Toddlers in Baungrejo Jaya Village Working Area of ​​Pelangiran Health Center in 2022
Authors: DELLAVEGA ANNISA SEPTYA , Syukaisih Syukaisih , Wahyuni Denai 
Published: December 2022

Wilayah Kerja UPT Puskesmas Pelangiran terdiri dari 1 kelurahan dan 15 desa. Dimana kejadian stunting tertinggi pertama berada di Desa Hidayah dengan prevalensi sebesar 50% , tertinggi kedua berada di Desa Baungrejo Jaya dengan prevalensi 46.25% dan tertinggi ketiga berada pada Desa Sungai Kateman dengan Prevalensi 41,67%. Tujuan penelitian ini secara umum adalah untuk mengetahui Hubungan Sarana Sanitasi Dan Perilaku Ibu Terhadap Kejadian Pendek (Stunting) Pada Balita Di Desa Baungrejo Jaya Wilayah Kerja Puskesmas Pelangiran Tahun 2022. Jenis penelitian ini adalah kuantitatif dan analitik observasional dengan desain penelitian cross sectional. Populasi seluruh balita di Wilayah Kerja Puskesmas Pelangiran sebanyak 100 orang ibu yang memiliki balita. Dilakukan wawancara dan observasi kepada 50 orang sampel secara quota sampling. Uji statistic yang digunakan adalah uji Chi square. Lokasi penelitian ini dilakukan di Desa Baungrejo Jaya Wilayah Kerja Puskesmas Pelangiran pada bulan Juli 2022. Hasil penelitian menunjukkan bahwa ada hubungan kepemilikan sarana air bersih (P value = 0,005; OR = 16.867), kepemilikan Jamban (P value = 0,045; OR = 6.176), kepemilikan SPAL (P value = 0,008; OR = 15,125), perilaku ibu (P value = 0,018; OR = 12,222). Dari hasil penelitian ini dapat disimpulkan bahwa semua variable berhubungan dengan kejadian stunting karena nilai P value <0,05 pada desa baungrejo jaya wilayah kerja puskesmas pelangiran.
PENGARUH PENERAPAN METODE PEMBELAJARAN SOSIODRAMA TERHADAP PEMAHAMAN BELAJAR IPS SISWA PADA MATERI INTERAKSI SOSIAL DAN KEHIDUPAN SOSIAL KELAS VIII Di MTS ASSALAAM MATARAM TAHUN PELAJARAN 2021/2022
Authors: Asari Hasim , Zainurrahman Muh , Fatriani Emilia 
Published: December 2022

Permasalahan dalam penelitian ini adalah pemahaman siswa dalam proses pembelajaran yang masih rendah dan hasil belajar siswa pada mata pelajaran IPS di kelas VIII yang tergolong masih rendah, sehingga penelitian ini bertujuan untuk mengetahui pengaruh penerapan metode pembelajaran sosiodrama terhadap pemahaman belajar IPS siswa pada materi interaksi sosial dan kehidupan sosial dikelas VIII MTS Assalaam dan untuk mengetahui apakah penerapan metode sosiodrama dapat meningkatkan pemahaman belajar IPS. Penelitian ini dilakukan di MTs Assalaam Mataram.Jenis penelitian yang digunakan pada penelitian ini yaitu quasi eksperimen dengan desain Nonequivalent control group design. Pengambilan sampel dilakukan dengan menggunakan Materi rujukan kelas VIII Semester satu kurikulum K13. Sampel pada penelitian ini ada 2 kelas yang terdiri dari 53 siswa yaitu kelas VIII A sebagai kelas eksperimen yang berjumlah 27 siswa dan kelas VIII B sebagai kelas kontrol yang berjumlah 26 siswa. Instrumen yang digunakan dalam penelitian ini yaitu instrumen observasi untuk mengukur aktivitas siswa dan instrumen tes objektif berupa pilihan ganda untuk mengukur hasil belajar. Hasil penelitian menunjukkan bahwa pembelajaran menggunakan metode pembelajaran sosiodrama/bermain peran (role playing) mempunyai perbedaan yang signifikan. Data dalam penelitian ini dianalisis menggunakan analisis kovariat (ANCOVA) dengan bantuan SPSS 22. Sebelum dilakukan analisis kovarian terlebih dahulu dilakukan uji prasyarat yang terdiri dari uji normalitas dan homogenitas. Berdasarkan analisis data yang dilakukan hasil uji ANCOVA pada aktivitas menunjukkan bahwa nilai sig yang diperoleh yaitu 0,002 sehingga 0,0020,05, sedangkan hasil analisis ANCOVA pada hasil belajar menunjukkan bahwa nilai sig. yang diperoleh yaitu 0,024 sehingga nilai sig. 0,0240,05. Sehingga dapat disimpulkan bahwa penggunaan metode pembelajaran sosiodrama dapat meningkatkan pemahaman siswa dan hasil belajar.
Chimeric Antigen Receptor T-cell Therapies in Lymphoma Patients with Central Nervous System Involvement
Authors: Yi Dongni , Gergis Mia , Elgohary Ghada , Hsu Jingmei , Yang Yang , Bi Xia , Gergis Usama 
Published: December 2022

Background and objective:
CAR T-cell therapy has significantly improved the outcomes of patients with relapsed or refractory (R/R) B-cell non-Hodgkin lymphoma (B-NHL). However, most clinical trials excluded patients with central nervous system (CNS) involvement due to uncertain efficacy and safety.

Material and methods:
On January 1, 2022, we searched PubMed to identify all published literature associated with current commercial CAR T-cell therapies for B-NHL, including tisagenlecleucel (tisa-cel), axicabtagene ciloleucel (axi- cel), brexucabtagene autoleucel (brexu-cel), and lisocabtagene maraleucel (liso-cel). Studies that involved patients with either primary or secondary CNS lymphoma, and evaluated response rate, adverse events (AEs), or survival were included and summarized.

Result:
Herein, we summarize the results of 11 studies qualified for our inclusion criteria, reporting 58 lymphoma patients with CNS Involvement with 44 evaluable for clinical response, 25 for immune effector cell-associated neurotoxicity syndrome (ICANS) and 48 for Cytokine release syndrome (CRS). Objective response was achieved in 62% (16/26) of patients, and CR was achieved in 52% (23/44) of patients. Forty-four percent (11/25) developed ICANS, and 35% (17/48) developed severe ICANS (grade≥3). CRS was reported in 63% (15/24) of patients, while severe CRS (grade>3) was reported in 7% (3/42) of patients.

Conclusion:
Based on our PubMed literature review, we conclude that CAR T-cell therapy may benefit patients with CNS lymphoma with promising response rates and acceptable AE. However, definite conclusions cannot be drawn until data with a larger sample size is available.