bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Star Formation Across Cosmic Time (SFACT) Survey. II. The First Catalog from a New Narrowband Survey for Emission-line Objects
Authors: Sieben Jennifer , Carr David J. , Salzer John J. , Hirschauer Alec S. 
Published: August 2023

Abstract
Star Formation Across Cosmic Time (SFACT) is a new narrowband (NB) survey designed to detect faint emission-line galaxies (ELGs) and QSOs over a broad range of redshifts. Here we present the first list of SFACT candidates from our pilot-study fields. Using the WIYN 3.5 m telescope, we are able to achieve good image quality with excellent depth and routinely detect ELGs to r = 25.0. The limiting line flux of the survey is ∼1.0 × 10−16 erg s−1 cm−2. SFACT targets three primary emission lines: Hα, [O iii] λ5007, and [O ii] λ3727. The corresponding redshift windows allow for the detection of objects at z ∼ 0–1. With a coverage of 1.50 deg2 in our three pilot-study fields, a total of 533 SFACT candidates have been detected (355 candidates deg−2). We detail the process by which these candidates are selected in an efficient and primarily automated manner, then tabulate accurate coordinates, broadband photometry, and NB fluxes for each source.
Systematic KMTNet Planetary Anomaly Search. IX. Complete Sample of 2016 Prime-field Planets
Authors: Shin In-Gu , Yee Jennifer C. , Zang Weicheng , Yang Hongjing , Hwang Kyu-Ha , Han Cheongho , Gould Andrew , Udalski Andrzej , Bond Ian A. ,   Leading authors, Albrow Michael D. , Chung Sun-Ju , Jung Youn Kil , Ryu Yoon-Hyun , Shvartzvald Yossi , Cha Sang-Mok , Kim Dong-Jin , Kim Seung-Lee , Lee Chung-Uk , Lee Dong-Joo , Lee Yongseok , Park Byeong-Gon , Pogge Richard W. ,   The KMTNet Collaboration, Mróz Przemek , Szymański Michał K. , Skowron Jan , Poleski Radosław , Soszyński Igor , Pietrukowicz Paweł , Kozłowski Szymon , Rybicki Krzysztof A. , Iwanek Patryk , Ulaczyk Krzysztof , Wrona Marcin , Gromadzki Mariusz ,   The OGLE Collaboration, Abe Fumio , Barry Richard , Bennett David P. , Bhattacharya Aparna , Fujii Hirosane , Fukui Akihiko , Hamada Ryusei , Hirao Yuki , Silva Stela Ishitani , Itow Yoshitaka , Kirikawa Rintaro , Kondo Iona , Koshimoto Naoki , Matsubara Yutaka , Miyazaki Shota , Muraki Yasushi , Olmschenk Greg , Ranc Clément , Rattenbury Nicholas J. , Satoh Yuki , Sumi Takahiro , Suzuki Daisuke , Tomoyoshi Mio , Tristram Paul J. , Vandorou Aikaterini , Yama Hibiki , Yamashita Kansuke ,   the MOA Collaboration
Published: August 2023

Abstract
As a part of the “Systematic KMTNet Planetary Anomaly Search” series, we report five new planets (namely, OGLE-2016-BLG-1635Lb, MOA-2016-BLG-532Lb, KMT-2016-BLG-0625Lb, OGLE-2016-BLG-1850Lb, and KMT-2016-BLG-1751Lb) and one planet candidate (KMT-2016-BLG-1855), which were found by searching 2016 KMTNet prime fields. These buried planets show a wide range of masses from Earth-class to super-Jupiter-class and are located in both the disk and the bulge. The ultimate goal of this series is to build a complete planet sample. Because our work provides a complementary sample to other planet detection methods, which have different detection sensitivities, our complete sample will help us to obtain a better understanding of planet demographics in our Galaxy.
Anisotropic Ionizing Illumination from an M-type Pre-main-sequence Star, DM Tau
Authors: Terada Yuka , Liu Hauyu Baobab , Mkrtichian David , Sai Jinshi , Konishi Mihoko , Jiang Ing-Guey , Muto Takayuki , Hashimoto Jun , Tamura Motohide 
Published: August 2023

Abstract
The powerful, high-energy magnetic activities of young stars play important roles in the magnetohydrodynamics in the innermost parts of the protoplanetary disks. In addition, the associated UV and X-ray emission dictates the photochemistry; moreover, the corona activities can affect the atmosphere of a newborn extrasolar planet. How the UV and X-ray photons are generated and how they illuminate the disks are not well understood. Here we report the analyses of the optical and infrared (OIR) photometric monitoring observations and the high angular resolution centimeter-band images of the low-mass (M1-type) pre-main-sequence star DM Tau. We found that the OIR photometric light curves present periodic variations, which suggests that the host young star is rotating in the same direction as the natal disk and is hosting at least one giant cold spot. In addition, we resolved that the ionized gas in the DM Tau disk is localized and its spatial distribution is varying with time. All the present observations can be coherently interpreted, if the giant cold spot is the dominant anisotropic UV and/or X-ray source that illuminates the ambient cone-like region. These results indicate that a detailed theoretical model of the high-energy protostellar emission is essential in understanding the space weather around extrasolar planets and the origin of life.
Assessment of patients’ awareness on drugs use and adherence to drug therapy as an element of Medication Review service
Authors: Petrova Galina , Todorova Anna , Georgiev Tihomir , Petkova-Gueorguieva Elina , Mihaylova Anna , Peikova Lily , Balkanski Stefan , Gueorguiev Stanislav 
Published: August 2023

The administration of an excessive amount of or unnecessary drugs is a prerequisite for numerous drug-related problems, non-compliance, non-adherence to medicinal therapy, exacerbation and poor control of chronic diseases, and failure in achieving the treatment goals. The aim of this study was to assess patients’ awareness on drug use (administration, adherence to drug therapy) and to identify the possible drug-related problems with patients, using 5 or more medicines on Bulgarian territory. The data were collected implementing a structured study tool – a questionnaire for assessment of patients’ therapy using 5 or more drugs prescribed by a physician, including OTC and/or food supplements. The study provided an identification of factors affecting skipping of doses, modification of regime and analyzed the relationships and interdependencies between number of diagnoses and adverse drug effects rate; number of administered drugs and reported problems and unawareness of the medicinal product indications and health state.
The results showed that it was necessary to introduce the Medication Review (MR) service in Bulgarian pharmaceutical practice. That will provide possibilities for development of pharmacists’ role in dispensing medical products, it will help in reducing drug-related problems and increasing the effectiveness of the treatment and adherence to medical therapy.
Spherical Aberration of Astigmatic Corneas in a Cataract Population
Authors: Baur Isabella D. , Auffarth Gerd U. , Khoramnia Ramin , Łabuz Grzegorz 
Published: August 2023

Purpose:
To study the distribution of spherical aberration (SA) in astigmatic corneas in a cataract population and the relationship between magnitude of corneal astigmatism and fourth-order corneal SA.

Methods:
Data routinely collected using a Scheimpflug camera (Pentacam; Oculus Optikgeräte GmbH) were retrospectively analyzed. Patients with a minimum age of 60 years were included. Total corneal SA (from anterior and posterior corneal surface) was obtained for a 6-mm cor-neal area aligned with the pupil center. Exclusion criteria were insufficient measurement quality, total deviation index (Belin/Ambrósio Deviation) greater than 1.60, and corneal thickness at the thinnest point of less than 490 μm. One eye per patient was chosen randomly. Eyes were divided into low (≤ 1.00 diopters [D]), moderate (> 1.00 to ≤ 2.00 D), and high (> 2.00 D) astigmatism groups according to the Scheimpflug measurements.

Results:

A total of 528 eyes were included in this analysis. Low astigmatism was found in 129 patients, moderate astigmatism in 265 patients, and high astigmatism in 134 patients. Mean astigmatism was 0.68 ± 0.24, 1.45 ± 0.28, and 2.91 ± 0.95 D in the low, moderate, and high astigmatism groups, respectively. Mean corneal SA in patients with moderate and high astigmatism was higher than in the low astigmatism group. The difference reached the significance level for the comparison of low and high astigmatism groups (
P
= .023). The fourth-order SA increased gradually with the magnitude of astigmatism with a slope of 0.015.

Conclusions:
SA was significantly larger in the cataract population with high corneal astigmatism. The increase of positive sign SA with the magnitude of astigmatism suggests that patients with moderate to high astigmatism may benefit more from intraocular lenses with negative sign SA correction.

[
J Refract Surg
. 2023;39(8):532–538.]
A Case Series of Infectious Keratitis After Corneal Cross-linking
Authors: Farrokhpour Hossein , Soleimani Mohammad , Cheraqpour Kasra , Masoumi Ahmad , Tabatabaei Seyed Ali , Shahriari Mansoor , Hobaby Sara , Baharnoori Seyed Mahbod , Chaudhry Ahmed , Djalilian Ali R. 
Published: August 2023

Purpose:
To present the 7-year experience of a tertiary eye hospital while exploring possible risk factors and incidence of infectious keratitis in patients undergoing standard corneal cross-linking (CXL).

Methods:
This retrospective cohort study included patients with progressive keratoconus undergoing standard CXL in the Farabi Eye Hospital and all other patients who had undergone CXL in other facilities and were diagnosed as having infectious keratitis in the 7-year period of the study.

Results:

Among the total of 4,863 eyes that underwent CXL, 6 eyes developed infectious keratitis, yielding an incidence rate of 0.12%. Additionally, 13 eyes from 10 patients with a CXL history in other facilities who developed infectious keratitis were included. The mean age was 23.75 years, and 75% of patients were men and 25% were women. Gram-positive bacteria and
Staphylococcus aureus
were the most prevalent pathogens. Meibomian gland dysfunction, dry eye disease, or blepharitis were present in 12 patients. Medical treatment did not arrest the disease progress in 5 patients, which eventually required cases to undergo keratoplasty.

Conclusions:
This study supports the need for proper patient selection by using a comprehensive medical history. It also highlights the imperative role of rigorous patient education and follow-up, particularly in the first postoperative week. Finally, the study emphasizes aggressive early therapy for patients with suspicious findings.

[
J Refract Surg
. 2023;39(8):564–572.]
Role of multimodal monitoring in the management of patients undergoing complex intracranial bypass procedures – A case series and literature review
Authors: Sreekumar Revikrishnan , Hrishi Ajay P , Sethuraman Manikandan 
Published: August 2023

ABSTRACT
Patients undergoing complex intracranial neurovascular procedures continue to have a high mortality rate. Individualised goal-directed cerebral resuscitation employing multimodality neuromonitoring may impact these patients’ treatment and prognosis. Advanced monitoring methods aid in the early identification of secondary brain insults and serve as endpoints for goal-directed therapy in the perioperative period. Unfortunately, there is a paucity of literature exploring the impact of multimodality monitoring and its outcome in these patients. We aim to present this case series wherein the patients had a favourable outcome post-intracranial complex bypass procedure, owing to goal-directed management guided by multimodality monitoring in the perioperative period.
Ultrasound-guided erector spinae plane block versus port site infiltration for postoperative pain and quality of recovery in adult patients undergoing laparoscopic cholecystectomy: An assessor-blinded randomised controlled trial
Authors: Joshi Yashita , Ramakrishnan Priya , Jindal Parul , Sachan Praveendra K. 
Published: August 2023

ABSTRACT

Background and Aim:
Pain following laparoscopic cholecystectomy (LC) is common and results in poor quality of recovery. Our study aimed to compare the analgesic efficacy of port site local infiltration, novel erector spinae plane (ESP) block, and standard regimen in patients undergoing LC and its impact on functional recovery.

Methods:
After ethical approval and registering the trial, we randomly allocated 105 adult patients undergoing LC to three groups: Group II (n = 35), received multimodal analgesia; Group II (n = 35), received pre-incisional port site infiltration with 20 ml of 0.375% bupivacaine; and Group III (n = 35), preoperative bilateral ESP block with 20 ml of 0.375% bupivacaine bilaterally was administered. Pain severity, fentanyl consumption, and time to first rescue analgesia were recorded over 24 h. Quality of recovery (QoR-15) was assessed at baseline and 24 h postoperatively.

Results:
Pain in the first 6 h was lowest in the ESP group (P < 0.001). Although static pain in the infiltration group was comparable with that in the ESP group after 6 h (P > 0.05), dynamic pain was better in the ESP group till 20 h postoperatively (P < 0.05). Fentanyl consumption was significantly lower in the ESP group (P < 0.001). Global and sub-dimensional QoR-15 scores were significantly higher only in the ESP group at 24 h compared to the other two groups (P < 0.001). The infiltration group did better than the control group in terms of total opioid requirement (P < 0.001) and Visual Analogue Scale (VAS) score after 6 h (P < 0.001).

Conclusion:
ESP block provided lower postoperative pain scores with opioid-sparing and better quality of recovery in patients undergoing LC.
Effect of Pranayama as per Trishikhbrahmana Upanishad on Sleep Quality in Adults: An Experimental Study
Authors: Tyagi Prakhar , Dubey Arpit Kumar , Pal Rameswar 
Published: August 2023

Context:
The Upanishads are primary texts of Yoga philosophy and practices. Various Yoga Upanishads have given detailed description of various yogic practices along with their spiritual and physical benefits. This study aims to assess the effect of one Pranayama practice from Trishikhbrahmana Upanishad on sleep quality in adults.

Aim:
The aim of the study was to assess the effect of a Pranayama technique (described in the Trishikhbrahmana Upanishad) on sleep quality in adults.

Settings and Design:
An experimental study was conducted on volunteer participants from North India.

Subjects and Methods:
A pretest–posttest control group study was designed where the participants (n = 30) were randomized into study (n = 15) and control (n = 15) groups. The study group was given the Pranayama intervention for 30 days whereas the control group was not given any intervention throughout the study. The sleep quality was assessed by using the Pittsburgh Sleep Quality Index (PSQI).

Statistical Analysis Used:
GraphPad Instat Software was used to carry out independent t-test. The mean and standard deviation were also calculated.

Results:
The results showed a significant improvement in the postglobal PSQI score in the study group (P < 0.001) whereas there was no significant change in the pre- and postglobal PSQI score in the control group (P = 0.941).

Conclusion:
The results suggest that the Pranayama technique from the text and its effects are true in improving the sleep quality in adults but future studies with a larger sample size and some other physiological parameter assessments may further support the textual claim.
Recurrent Bleeding in a Healthy Child-A Case of Lupus Anticoagulant-Hypoprothrombinemia Syndrome
Authors: Kumar Sudesh , Bhattacharya Piyali , Gautam Shreemant , Chattopadhyay Nandita 
Published: August 2023

Background:
Although lupus anticoagulant (LA) is known to be associated with an increased risk of thrombosis and obstetric complications, typically seen in antiphospholipid syndrome, the presentation of LA-hypoprothrombinemia syndrome (LA-HPS) is different with bleeding manifestations more common than thrombosis. We report such a rare disorder in an otherwise healthy boy, who presented with subcutaneous bleeding and was treated successfully.

Clinical Description:
A 9-year-old boy presented with acute-onset swelling in the popliteal fossa region of the left leg and left great toe. History of fever, trauma, drug intake, joint pain, epistaxis, or melena was absent. Since 6 months of age, he had recurrent episodes of multiple, painful joint, and soft-tissue swellings and ecchymotic patches which subsided spontaneously. Examination showed a tense, shiny bluish patch over the left popliteal fossa and a swollen tender left great toe, without any lymphadenopathy, hepatosplenomegaly, or arthritis.

Management and Outcome:
Routine hemogram and liver function tests were normal. Furthermore, antinuclear antibody and rheumatoid factor were within normal limits. Coagulation studies showed prolonged prothrombin time (PT) and activated partial thromboplastin time (APTT), though bleeding and coagulation times were normal. Administration of Vitamin K and fresh frozen plasma (FFP) showed no improvement. Further investigations revealed normal values of von Willebrand Factor collagen binding, Factor VIII, Factor XIII, and fibrinogen, whereas prothrombin levels were reduced. The partial thromboplastin time-LA specific was high (170.10), suggesting a diagnosis of LA-HPS. The symptoms responded to prednisolone therapy, and there was complete recovery.

Conclusion:
A recurrent bleeding disorder with increased PT/APTT, not responding clinically to FFP transfusion, should raise suspicion of LA-HPS and appropriate tests need to be done. The prognosis of this disorder is good with corticosteroid therapy.
Simultaneous Occurrence of Noma in Identical Twin Brothers
Authors: Bala Mujtaba , Braimah Ramat Oyebunmi , Bello Abubakar Abdullahi , Taiwo Abdurrazaq Olanrewaju , Suleiman Ibrahim Kayode 
Published: August 2023

Background:
Noma is a devastating orofacial gangrenous condition that may cause significant mutilation of the facial anatomy. The pathogenesis is poorly understood and has been reported in a setting of low socioeconomic and unhygienic conditions with associated malnutrition. We present this condition in identical twin brothers.

Clinical Description:
Two identical twin brothers presented with painful swelling of the cheek with ulcerative defects in their upper lips. Both belonged to an impoverished family, and were malnourished, unimmunized, with poor oral hygiene. The typical anatomical presentation of the lesions with the characteristic family setting made the diagnosis consistent with noma (cancrum oris). Other siblings living in the same family with similar background conditions were unaffected.

Management:
After clinical stabilization, definitive surgical care, including debridement and regular dressings was done under the cover of intravenous antibiotics. With aggressive management along with nutritional rehabilitation and oro-muscular physiotherapy, the acute phase subsided and the patients were discharged in the scarring phase, with a plan for surgical reconstruction of the defect at a later date.

Conclusions:
The simultaneous presentation of noma in identical twins, with the sparing of other siblings living in the same contributing circumstances, raises suspicion of a genetic basis for this condition, which is as yet unknown. As the etiopathogenesis of noma is evolving, further evidence is needed to establish a genetic predisposition.
Acute Liver Failure as a Presenting Feature in an Adolescent with Acute Lymphoblastic Leukemia
Authors: Bhatnagar Simran , Kumar Bharat , Kumar Nitish , Hemal Alok 
Published: August 2023

Background:
Acute lymphoblastic leukemia (ALL) is a common pediatric malignancy, typically manifesting with symptoms of bone marrow and hematolymphoid organ infiltration. Although hepatic involvement in the form of hepatosplenomegaly is seen in nearly two-thirds of the patients, primary presentation as acute liver failure is rare.

Clinical Description:
A 12-year-old boy presented with complaints of abdominal distention with jaundice for the past 15–20 days, associated with transient fever of 6 days. Examination revealed pallor, icterus, and hepatosplenomegaly. A possibility of acute infectious or autoimmune hepatitis or hemolytic anemia was considered.

Management:
Liver function tests were deranged with hyperbilirubinemia with modest increase in transaminases and serum alkaline phosphatase along with deranged prothrombin time. The complete blood count showed pancytopenia with normal peripheral smear. Investigations for common infectious causes were noncontributory, as also those for autoimmune hepatitis. The direct Coombs test was also negative. In view of persistent pancytopenia with hyperbilirubinemia and hepatosplenomegaly, a bone marrow evaluation was done, which revealed B-cell ALL (B-ALL). Thus, the child was diagnosed with a case of ALL presenting with acute liver failure. The child was initially managed as a case of acute liver failure and on diagnostic confirmation, he was started on the B-ALL chemotherapy protocol as per his risk stratification with hepatic dose modification of chemotherapy. The child showed complete normalization of the liver functions by about 4 weeks of induction chemotherapy and achieved remission.

Conclusions:
A child presenting with acute liver failure may be having an underlying undiagnosed, clinically silent ALL. After ruling out common causes of acute liver failure, one must not forget the possibility of leukemic blast infiltration of the liver as a cause of liver failure. With early initiation of advanced chemotherapeutic induction regimens, there can be dramatic resolution of liver injury and remission of ALL.
Jarcho–Levin Syndrome
Authors: Prabhakar Nishant , Patel Brijesh 
Published: August 2023

Background:
Jarcho–Levin syndrome (JLS) is a rare, congenital skeletal disorder involving the spine and the ribs, resulting in varying degrees of thoracic insufficiency, presenting at birth. We report such a case in a tribal population in India.

Clinical Description:
A newborn baby was referred on the 2nd day of life with respiratory distress and abnormal thoracic anatomy. Radiographs of the chest showed anomalies of the spine and ribs and decreased lung volume, the features being consistent with JLS (spondylocostal dysostosis).

Management:
The baby was provided respiratory support initially with continuous positive airway pressure and then shifted to oxygen by nasal prongs by 7 days of life. Ultrasound cranium and abdomen did not reveal any other associated anomalies and routine blood investigations were within normal limits. Respiratory distress settled and the baby was finally discharged successfully on the 12th day, on breastfeeds.

Conclusion:
Respiratory distress in a newborn, soon after birth, may be due to thoracic insufficiency. The case creates awareness among pediatricians and neonatologists regarding this rare disorder which can be identified by specific vertebral and rib abnormalities. Survival depends on the severity of the bony abnormality and compromise in lung volume.