bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experience of coercion among nursing professionals in a medium‐stay mental health unit: A qualitative study in Spain
Authors: Aragonés‐Calleja Miriam , Sánchez‐Martínez Vanessa 
Published: March 2023

Accessible SummaryWhat is known on the subject?

Coercive measures represent an ethical conflict because they limit the person's freedom, compromising their personal autonomy, self‐determination and fundamental rights.

The reduction of the use of coercive measures implies not only regulations and mental health systems, but also cultural aspects, such as societal beliefs, attitudes, and values.

There is evidence about the professionals' views on coercion in acute mental health care units and community settings, but they remain unexplored in inpatient rehabilitation units.

What the paper adds to existing knowledge?

The knowledge about coercion varied from not knowing at all the meaning of the word, to a proper description of the phenomenon.

Coercive measures are considered a necessary evil or normalized in mental health care and considered implicit to daily practice.

What are the implications for practice?

The perceptions and attitudes towards coercion might be influenced by the knowledge about the phenomenon. Training of mental health nursing staff in non‐coercive practice could help professionals to detect, be conscious towards, and question coercive measures, thus orienting them to the effective implementation of interventions or programmes with evidenced effectiveness to reduce them.

AbstractIntroductionCreating a therapeutic and safe milieu with the minimum coercive measures requires knowing professionals' perceptions and attitudes towards coercion, but they remain unexplored in medium and long‐stay inpatient psychiatric rehabilitation units.AimTo explore the knowledge, perception and experience of coercion among nursing staff at a rehabilitation medium‐stay mental health unit (MSMHU) in Eastern Spain.MethodQualitative phenomenological study including 28 face‐to‐face, semi‐structured interviews based on a script. Data were analysed using content analysis.ResultsTwo main themes were found: (1) therapeutic relationship and treatment in the MSMHU, which included three subthemes: qualities of the professionals for building the therapeutic relationship; perceptions about the persons admitted to the MSMHU; views of the therapeutic relationship and treatment in the MSMHU; (2) Coercion at the MSMHU, comprising five subthemes: professional knowledge; general aspects; emotional impact of coercion; opinions; alternatives.DiscussionCoercive measures are often normalized in mental health care and considered implicit to daily practice. A proportion of participants who did not know what coercion is.Implications for PracticeKnowledge about coercion might influence attitudes towards coercion. Mental health nursing staff could benefit from formal training in non‐coercive practice, facilitating the operative implementation of effective interventions or programmes.
How many are they? Estimates of demographic patterns of reproductive females of southern right whale (Eubalaena australis) in the southern coast of Brazil
Authors: Renault‐Braga Eduardo P. , Groch Karina R. , Simões‐Lopes Paulo C. 
Published: March 2023

AbstractSouthern right whales use the Brazilian coast as a wintering area. This population was severely depleted by whaling up until 1973. Since the 1980s, studies have shown that this species is now restricted to the southern waters of Brazil. Using photo‐identification data obtained via standardized aerial surveys from Florianópolis, State of Santa Catarina (SC) (−27.797°/−48.533°) to Torres, State of Rio Grande do Sul (RS) (−29.396°/−49.763°), mark‐recapture methods were used to estimate survival capture and recruitment probability, population size using the POPAN model for reproductive females. Data were collected between 2004 and 2021. The final model was selected based on the lowest Akaike Information Criterion value. Of the 396 female whales identified, 41.41% were recaptured at least once. The final POPAN model showed time dependence in all parameters. The population size was estimated to be 397 reproductive females. This is the first update on the population trends for southern right whales in Brazilian breeding grounds since 2010.
Traditional summer habitat use by Southern Resident killer whales in the Salish Sea is linked to Fraser River Chinook salmon returns
Authors: Stewart Joshua D. , Cogan Jane , Durban John W. , Fearnbach Holly , Ellifrit David K. , Malleson Mark , Pinnow Melisa , Balcomb Kenneth C. 
Published: March 2023

AbstractSouthern Resident killer whales (SRKW, Orcinus orca) are a small, endangered population of fish‐eating killer whales that inhabit coastal and inland waters of the western United States and British Columbia. SRKW have been in decline since 1995, with food availability, vessel disturbance, and pollutants proposed as drivers of their decline. We used 17 years of sightings data from the SRKW core summer habitat in the Salish Sea to examine trends in presence of SRKW, and how these trends may be related to the availability of a key food source, Fraser River‐origin Chinook salmon. We found that SRKW occupancy has declined by more than 75%, in step with reduced average catch per unit effort (CPUE) of Fraser River Chinook salmon. J pod was present in the core summer habitat most often, followed by K and L pods. All three pods demonstrated declines in visitation to the core summer habitat from 2004 to 2020, and presence of SRKW was significantly related to annual average Fraser Chinook CPUE. Our findings suggest that declining Fraser River Chinook returns may be reaching a point where SRKW cannot reliably meet their energetic needs, driving them to forage in areas outside of their traditional core summer habitat.
Tendril morphogenesis is regulated by a CsaTEN–CsaUFO module in cucumber
Authors: Hong Zezhou , Wang Xinrui , Yang Aiyi , Yan Guochao , He Yong , Zhu Zhujun , Xu Yunmin 
Published: March 2023

Summary

Tendril is a morphological innovation during plant evolution, which provides the plants to obtain climbing ability. However, the tendril morphogenesis is poorly understood.

A novel tendril morphogenesis defective mutant (tmd1) was identified in cucumber. The apical part of tendril was replaced by a leaf blade in tmd1 mutant, and it lost the climbing ability. Map‐based cloning, qPCR detection, bioinformatic analysis, yeast one‐hybrid assay, electrophoretic mobility shift assay, and luciferase assay were used to explore the molecular mechanism of CsaTMD1 in regulating tendril morphogenesis.

CsaUFO was the candidate causal gene, and a fragment deletion within promoter impaired CsaUFO expression in tmd1 mutant. A conserved motif 1, which harbored two putative TCP transcription factor binding sites, was located within this deleted fragment. CsaTEN directly bound the motif 1 and positively regulated CsaUFO, and mutation in motif 1 removed this regulation.

Our work shows a CsaTEN–CsaUFO module in regulating tendril morphogenesis, indicating that evolution of tendril in cucumber due to simply drive of CsaUFO by CsaTEN in tendril. Additionally, the conserved motif 1 provides a strategy for engineering tendril‐less Cucurbitaceae crops.
Enhanced Recovery after Total Joint Arthroplasty (TJA): A Contemporary Systematic Review of Clinical Outcomes and Usage of Key Elements
Authors: Changjun Chen , Jingkun Li , Yun Yang , Yingguang Wu , Yanjun Ren , Debo Zou , Kaining Zhang , Pengde Kang 
Published: March 2023

BackgroundEnhanced recovery after surgery (ERAS) is a pathway designed to improve the care of surgical patients and achieve early recovery. The clinical outcomes and usage of key elements of ERAS pathways in total joint arthroplasty (TJA) need further reanalysis. This article aims to provide an overview of the latest clinical outcomes and current usage of key elements of ERAS pathways in TJA.MethodsWe undertook a systematic review of the PubMed, OVID, and EMBASE databases in February 2022. Studies investigating the clinical outcomes and usage of key elements of ERAS in TJA were included. The components of successful ERAS programs and their usage were further determined and discussed.ResultsTwenty‐four studies involving 216,708 patients assessed ERAS pathways for TJA. A total of 95.8% (23/24) of studies reported a reduced length of stay (LOS), followed by reduce overall opioid consumption or pain (87.5% [7/8]), save costs (85.7% [6/7]), improvements in patient‐reported outcomes or functional recovery (60% [6/10]), and reduced incidence of complications (50% [5/10]). In addition, preoperative patient education (79.2% [19/24]), anesthetic protocol (54.2% [13/24]), use of local anesthetics for infiltration analgesia or nerve blocks (79.2% [19/24]), perioperative oral analgesia (66.7% [16/24]), perioperative surgical factors including reduced use of tourniquets and drains (41.7% [10/24]), use of tranexamic acid (41.7% [10/24]) and early mobilization (100% [24/24]) were contemporary comparatively “active” components of ERAS.ConclusionsERAS for TJA has favorable clinical outcomes in terms of reducing LOS and overall pain, saving costs, accelerating functional recovery, and reducing complications, although the evidence is still low in quality. In the current clinical scenario, only some “active” components of the ERAS program are widely used.
Infantile perianal pyramidal protrusion: A retrospective review of 27 patients
Authors: Dhami Ramneek K. , Isaq Nasro A. , Tollefson Megha M. 
Published: March 2023

AbstractBackgroundInfantile perianal pyramidal protrusion (IPPP) is a rare benign skin condition that is typically seen in infant girls. This condition is often mistaken for other skin lesions such as acrochordons, condyloma acuminatum, and sequelae of sexual abuse. Many clinicians are unfamiliar with IPPP which can lead to aggressive workup and treatment. The purpose of this study was to elucidate demographic data, clinical features, diagnostic workup, and management of IPPP in a large cohort of patients seen at an academic medical center.MethodsA retrospective review of patients diagnosed with IPPP at Mayo Clinic, Rochester, MN was conducted. Demographic data, examination findings, diagnostic workup, and treatments were noted.ResultsTwenty‐seven patients with IPPP, 24 of which were girls and 3 were boys from the ages of 1 day to 4 years (mean 10.8 months, median 8.6 months) were identified. Symptoms were reported in 63% (17/27) of patients. Four patients received treatment with topical corticosteroid or local anesthetic. No patient underwent skin biopsy.ConclusionIPPP is commonly observed in healthy prepubertal girls. Constipation is a common symptom. Awareness of this entity may prevent overtreatment and unnecessary evaluation.
Geographic isolation and climatic heterogeneity drive population differentiation of Rosa chinensis var. spontanea complex
Authors: Li S. Q. , Zhang C. , Gao X. F. 
Published: March 2023

ABSTRACT

Global biodiversity is contracting rapidly due to potent anthropogenic activities and severe climate change. Wild populations of Rosa chinensis var. spontanea and Rosa lucidissima are rare species endemic to China, as well as important germplasm resources for rose breeding. However, these populations are at acute risk of extinction and require urgent action to ensure their preservation.

We harnessed 16 microsatellite loci to 44 populations of these species and analysed population structure and differentiation, demographic history, gene flow and barrier effect. In addition, a niche overlap test and potential distribution modelling in different time periods were also carried out.

The data indicate that: (1) R. lucidissima cannot be regarded as a separate species from R. chinensis var. spontanea; (2) the Yangtze River and the Wujiang River function as barriers in population structure and differentiation, and precipitation in the coldest quarter may be the key factor for niche divergence of R. chinensis var. spontanea complex; (3) historical gene flow showed a converse tendency to current gene flow, indicating that alternate migration events of R. chinensis var. spontanea complex between south and north were a response to climate oscillations; and (4) extreme climate change will decrease the distribution range of R. chinensis var. spontanea complex, whereas the opposite will occur under a moderate scenario for the future.

Our results resolve the relationship between R. chinensis var. spontanea and R. lucidissima, highlight the pivotal roles of geographic isolation and climate heterogeneity in their population differentiation, and provide an important reference for comparable conservation studies on other endangered species.
Geological and hypogene mineralization characteristics of the hematite‐rich Pelusa IOCG prospect, Antofagasta Region, Northern Chile
Authors: Carvajal Nicolás , Kojima Shoji , Vallejo Alejandro , Ildefonso Freddy 
Published: March 2023

AbstractThe Japón, Tailandia and China Sur deposits in the Pelusa mineralized area correspond to a hematite‐dominant IOCG clan within the coastal Cordillera in the Antofagasta Region, Northern Chile, and their mineralization occurs in basaltic to andesitic volcanic rocks of the Jurassic La Negra Formation. In addition to geological and mineralogical descriptions, bulk chemistry of the host rocks, microthermometric and sulfur isotropic analyses were performed to elucidate ore‐forming characteristics of the three orebodies. Chemical data of the host rocks indicate a subalkaline calc‐alkaline affinity with enrichment of the incompatible LILEs, displaying a typical pattern of igneous rocks formed in subduction zones as a general characteristic of the Jurassic‐Lower Cretaceous magmatic arc. Chalcopyrite is the predominant hypogene copper mineral, that variously occurs as veinlets, disseminations and breccia matrix. Fluid inclusions data indicate formation temperatures of the hypogene mineralization ranging mostly from 186 to 377°C, with a high‐salinity range of 30.1 and 45.0 wt% NaCl. The sulfur isotopic ratios (δ34SCDT) of pyrite and chalcopyrite present a narrow range of values from −10.6 to −7.5‰. The negative values in the limited range imply that sulfide minerals of the Pelusa area were formed under a relatively oxidizing and/or neutral pH condition, compared with other Chilean IOCG deposits.
Trends in the use of home care services among Norwegians 70+ and projections towards 2050: The HUNT study 1995–2017
Authors: Chang Milan , Michelet Mona , Skirbekk Vegard , Langballe Ellen M. , Hopstock Laila A. , Sund Erik R. , Krokstad Steinar , Strand Bjørn H. 
Published: March 2023

AbstractBackgroundLife expectancy (LE) is increasing worldwide, while there is lack of information on how this affects older individuals' use of formal home care services.AimWe aimed to decompose LE into years with and without home care services and estimate projected number of users towards 2050 in Norway for people 70 years or older.MethodsThis study is based on a sample of 25,536 participants aged 70 years and older in the Trøndelag Health Study (HUNT) survey 2 (1995–1997), 3 (2006–2008), or 4 (2017–2019) linked with national data on mortality. Prevalence of home care services was standardised to the Norwegian population by age and sex. The Sullivan method was used to estimate expected years with and without home help services and nursing services for the years 1995, 2006 and 2016. Data from HUNT4 and Statistics Norway were used to estimate projected use of these services between 2020 and 2050.ResultsDuring 1995–2017, the use of home help services decreased from 22.6% to 6.2% (p < 0.001), and from 6.4% to 5.5% (p = 0.004) for home nursing services. Adjusted for age and sex, the use of home help services decreased significantly over time (p < 0.001), while home nursing services were stable (p = 0.69). LE at age 70 increased from 11.9 to 15.3 years in men (p < 0.05) during 1995–2017, and from 14.7 to 17.1 in women (p < 0.05). In the same period, the expected years receiving home help decreased from 2.6 to 1.1 in men (p < 0.05), and from 4.4 to 2.1 in women (p < 0.05). The expected years receiving home nursing increased from 0.6 to 0.9 in men (p < 0.05), and from 1.3 to 1.7 in women (p < 0.05). Projected numbers of people 70+ in Norway in need of either of these services were estimated to rise from 64,000 in 2020 to 160,000 in 2050.ConclusionWhile overall life expectancy increased, the expected years receiving home help have decreased and home nursing slightly increased among the Norwegian population aged 70 years and older during 1995–2017. However, the substantial increase in the projected number of older adults using home care services in the future is an alert for the current health care planners.
Hemolytic disease of the newborn due to anti‐Jra from a Chinese mother with one novel and one classic heterozygous mutation
Authors: Xiao Jie , Yang Qixiu , Gao Shouxi , Song Hui , Zhao Fengyong , Guo Zhonghui , Zhang Yuyu , Zhu Ziyan , Ye Luyi , Xiang Dong 
Published: March 2023

AbstractObjectiveInvestigation of a Jr(a‐) family samples, identification of the mutant and assessment of the differences of Jr antigen density of the Jr(a‐) family members, random adult and newborn individuals' RBCs.BackgroundThe anti‐Jra antibody is generated when a Jr(a‐) individual pregnant or transfused with Jr(a+) blood unit, which can lead to mild‐to‐moderate hemolytic disease of the foetus and newborn (HDFN) or hemolytic transfusion reaction (HTR). Several mutations had been identified. The anti‐Jra caused HDFN is not rare in East Asia, but due to the lack of antibody and molecular background, it is likely to lead missed detection.Methods and MaterialsOne G4P1 woman had been detected as IAT positive during prenatal examination. Suspected as anti‐Jra after the laboratory serological testing, the maternal sample was further assessed by molecular analysis. The antigen density was detected by flow cytometry after reacting with anti‐Jra serum in family members and the normal individuals.ResultsOne novel frameshift mutation c.717delC and one previously identified mutation c.706C > T in ABCG2 was identified on proband. The infant haemoglobin(Hb) and bilirubin increased significantly after exchange transfusion and the severe HDFN was relieved. Flow cytometry results showed that the Jra antigens on adult RBCs were significantly less than those on the infant.ConclusionThe c.717delC mutation can lead to the shortening of protein ABCG2 in the site of p.Leu307Stop, result in the loss of Jra antigen. The difference in antigen density between adult and infant RBCs may be a possible reason that leads to severe HDFN but not transfusion reaction. Breastfeeding may lead to slower recovery from HDFN.
Chromosome‐scale de novo genome assembly and annotation of three representative Casuarina species: C. equisetifolia, C. glauca, and C. cunninghamiana
Authors: Zhang Yong , Wei Yongcheng , Meng Jingxiang , Wang Yujiao , Nie Sen , Zhang Zeyu , Wang Huiyuan , Yang Yongkang , Gao Yubang , Wu Ji , Li Tuhe , Liu Xuqing , Zhang Hangxiao , Gu Lianfeng 
Published: March 2023

SUMMARYAustralian pine (Casuarina spp.) is extensively planted in tropical and subtropical regions for wood production, shelterbelts, environmental protection, and ecological restoration due to their superior biological characteristics, such as rapid growth, wind and salt tolerance, and nitrogen fixation. To analyze the genomic diversity of Casuarina, we sequenced the genomes and constructed de novo genome assemblies of the three most widely planted Casuarina species: C. equisetifolia, C. glauca, and C. cunninghamiana. We generated chromosome‐scale genome sequences using both Pacific Biosciences (PacBio) Sequel sequencing and chromosome conformation capture technology (Hi‐C). The total genome sizes for C. equisetifolia, C. glauca, and C. cunninghamiana are 268 942 579 bp, 296 631 783 bp, and 293 483 606 bp, respectively, of which 25.91, 27.15, and 27.74% were annotated as repetitive sequences. We annotated 23 162, 24 673, and 24 674 protein‐coding genes in C. equisetifolia, C. glauca, and C. cunninghamiana, respectively. We then collected branchlets from male and female individuals for whole‐genome bisulfite sequencing (BS‐seq) to explore the epigenetic regulation of sex determination in these three species. Transcriptome sequencing (RNA‐seq) revealed differential expression of phytohormone‐related genes between male and female plants. In summary, we generated three chromosome‐level genome assemblies and comprehensive DNA methylation and transcriptome datasets from both male and female material for three Casuarina species, providing a basis for the comprehensive investigation of genomic diversity and functional gene discovery of Casuarina in the future.
Parent perceptions of emergent blood transfusion in children
Authors: Morgan Katrina M. , Lobo Rachel , Annen Kyle , Villarreal Ricardo I. , Chou Stella , Uter Stacey , Leonard Julie C. , Dyer Cameryn , Yazer Mark , Spinella Philip C. , Leeper Christine M. 
Published: March 2023

AbstractBackgroundRhD‐negative blood products are in chronic short supply leading to renewed interest in utilizing RhD‐positive blood products for emergency transfusions. This study assessed parental perceptions of emergency RhD‐positive blood use in children.MethodsA survey of parents/guardians was conducted on their tolerance of transfusing RhD‐positive blood to RhD‐negative female children ≤17 years old at four level 1 pediatric hospitals.ResultsIn total, 621 parents/guardians were approached of whom 378/621 (61%) completed the survey in its entirety and were included in the analysis. Respondents were mostly females [295/378 (78%)], White [242/378 (64%)], had some college education [217/378 (57%)] and less than $60,000 annual income [193/378 (51%)]. Respondents had a total of 547 female children. Most children's ABO [320/547 (59%)] and RhD type [348/547 (64%)] were not known by their parents; of children with known RhD type, 58/186 (31%) were RhD‐negative. When the risk of harm to a future fetus was given as 0–6%, more than 80% of respondents indicated that they were likely to accept RhD‐positive blood transfusions on behalf of RhD‐negative female children in a life‐threatening situation. The rate of willingness to accept emergent RhD‐incompatible blood transfusions significantly increased as the potential survival benefit of the transfusion increased.ConclusionMost parents were willing to accept RhD‐positive blood products on behalf of RhD‐negative female children in an emergency situation. Further discussions and evidence‐based guidelines on transfusing RhD‐positive blood products to RhD‐unknown females in emergency settings are needed.
The effects of digital trade policies on digital trade
Authors: Suh Jeongmeen , Roh Jaeyoun 
Published: March 2023

AbstractAs digital trade expands worldwide, the importance of policy factors in digital trade is garnering attention. However, the effectiveness of digital trade‐related policies on digital trade flow is empirically underinvestigated because of challenging data requirements. To overcome this, we combine recently developed, but separately used digital trade‐related datasets to empirically test how digital trade policies affect digital trade flows. In particular, we examine the effects of digital trade policies from two dimensions: unilateral domestic regulations and bilateral trade agreements. Our results reveal that a pair of countries experiences an increase in digital trade flow when they have a trade agreement containing digital trade‐related provisions. This tendency is even stronger when digital trade agreements contain more specific rules. On the contrary, domestic regulations recognised as digital trade barriers actually inhibit digital trade flows, and their negative effect is greater when the regulations are implemented by the importing country than the exporting one. Decomposing the barriers into several areas of regulations, we examine which area is more crucial than the others. These results may seem rather obvious, but conversely, they confirm the validity of our approach to measure digital trade flows across countries and the relevance of the digital trade policy variables.