bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible Antiswelling Photothermal‐Therapy MXene Hydrogel‐Based Epidermal Sensor for Intelligent Human–Machine Interfacing
Authors: Zhang Yunfei , Xu Zhishan , Yuan Yue , Liu Chaoyong , Zhang Ming , Zhang Liqun , Wan Pengbo 
Published: February 2023

AbstractConductive hydrogel‐based epidermal sensors are regarded with broad prospects in bridging the gap between human and machine for personalized healthcare. However, it is still challenging to simultaneously achieve high sensitivity, wide sensing range, and reliable cycling stability in hydrogel‐based epidermal sensors for ultrasensitive human–machine interfacing, along with brilliant antiswelling capability, and near‐infrared (NIR) light‐triggered dissociation and drug release for further smart on‐demand photothermal therapy. Herein, the facile preparation of a flexible multifunctional epidermal sensor from the elaborately fabricated, highly stretchable, and antiswelling MXene hydrogel is presented. It exhibits high sensitivity, wide sensing range (up to 350% strain), and reliable reproducibility for enabling ultrasensitive human‐machine interfacing. It displays excellent antiswelling capability for the hydrogel to avoid expanding the wound due to excessive swelling for further reliable wound therapy. Furthermore, it possesses good biocompatibility and robust photothermal performance for the smart photothermal therapy after healthcare monitoring. Meanwhile, the sensor can be triggered to be softened and partly dissociated under the prolonged NIR light irradiation with the transformation of the temperature‐sensitive low‐melting‐point Agar into a sol state and the partial dissociation in the hydrogel to release the loaded drug on demand for synergistically sterilizing bacteria and efficiently promoting wound healing.
Poly‐Catecholic Functionalization of Biomolecules for Rapid Gelation, Robust Injectable Bioadhesion, and Near‐Infrared Responsiveness
Authors: Montazerian Hossein , Hassani Najafabadi Alireza , Davoodi Elham , Seyedmahmoud Rasoul , Haghniaz Reihaneh , Baidya Avijit , Gao Wei , Annabi Nasim , Khademhosseini Ali , Weiss Paul S. 
Published: February 2023

AbstractMussel‐inspired catechol‐functionalization of degradable natural biomaterials has garnered significant interest as an approach to achieve bioadhesion for sutureless wound closure. However, conjugation capacity in standard coupling reactions, such as carbodiimide chemistry, is limited by low yield and lack of abundant conjugation sites. Here, a simple oxidative polymerization step before conjugation of catechol‐carrying molecules (i.e., 3,4‐dihydroxy‐l‐phenylalanine, l‐DOPA) as a potential approach to amplify catechol function in bioadhesion of natural gelatin biomaterials is proposed. Solutions of gelatin modified with poly(l‐DOPA) moieties (GelDOPA) are characterized by faster physical gelation and increased viscosity, providing better wound control on double‐curved tissue surfaces compared to those of l‐DOPA‐conjugated gelatin. Physical hydrogels treated topically with low concentrations of NaIO4 solutions are crosslinked on‐demand via through‐thickness diffusion. Poly(l‐DOPA) conjugates enhance crosslinking density compared to l‐DOPA conjugated gelatin, resulting in lower swelling and enhanced cohesion in physiological conditions. Together with cohesion, more robust bioadhesion at body temperature is achieved by poly(l‐DOPA) conjugates, exceeding those of commercial sealants. Further, poly(l‐DOPA) motifs introduced photothermal responsiveness via near‐infrared (NIR) irradiation for controlled drug release and potential applications in photothermal therapy. The above functionalities, along with antibacterial activity, render the proposed approach an effective biomaterial design strategy for wound closure applications.
Eumelanin‐Coated Aligned PLA Electrospun Microfibers to Guide SH‐SY5YCells Spreading, Alignment, And Maturation
Authors: Mariano Anna , Fasolino Ines , Dinger Nikita Bhupesh , Latte Bovio Claudia , Bonadies Irene , Pezzella Alessandro , Ambrosio Luigi , Raucci Maria Grazia , Santoro Francesca 
Published: February 2023

AbstractDuring the development of the nervous system, neurons sense and respond to topographical and biochemical cues found in the brain's native environment. Such niche‐specific cues are pivotal for neural tissue formation and development and have been now widely exploited in neural tissue engineering to develop biologically‐inspired scaffolds able to trigger a desired neuronal behavior. In particular, anisotropic aligned fibers, recapitulating the design of extending axonal tracts or aligned fibers found in the extracellular environment, have emerged as ideal candidates to guide cell alignment and elongation along the substrate main axis as well as promote neuronal differentiation. Among natural polymers used for coatings, melanins, including eumelanin, have been shown to possess antioxidant, anti‐inflammatory, immunomodulatory, and photo‐protective properties. Here, aligned poly(lactic acid) (PLA) fibers are fabricated via electrospinning and then coated with eumelanin via spin coating. Eumelanin‐coated aligned PLA fibers are highly biocompatible and greatly influenced the adhesion, morphology, and spreading of SH‐SY5Y neuroblastoma cells. Furthermore, the eumelanin coating is crucial in promoting cell alignment at the cell‐material interface and SH‐SY5Y cell maturation towards a more mature neuronal phenotype.
Triboelectric Mechanism of Oil‐Solid Interface Adopted for Self‐Powered Insulating Oil Condition Monitoring
Authors: Xiao Song , Wu Haoying , Li Nan , Tan Xiangyu , Deng Haocheng , Zhang Xiaoxing , Tang Ju , Li Yi 
Published: February 2023

AbstractThe liquid‐solid contact electrification mechanism has been explored in the aqueous solution system, but there are few systematic studies on oil‐solid triboelectrification. Herein, an oil droplet triboelectric nanogenerator (Oil‐droplet TENG) is designed as the probe to investigate the charge transfer properties at oil‐solid interface. The charge transfer kinetics process is disclosed by the electrical signals produced, showing that the electron species initially predominated the oil‐solid triboelectrification. The molecular structure and electronic properties of oil also affect triboelectric performance. Further, the charge transfer principle in multi‐component liquid mixture during the electric double layer (EDL) development process is proposed to explain the component competition effect. As a proof of concept, a tubular‐TENG is designed as a self‐powered sensor for transformer oil trace water detection. The device demonstrates high water sensitivity with a detection limit of 10 µL L−1 and a response range of 10–100 µL L−1. This work not only reveals the oil‐solid triboelectric and charge transfer competition mechanism in EDL, but also open up a new channel for real‐time online monitoring of trace water in transformer oil, which holds promise for information perception and intelligent operation of transformers in the power industry.
Macrocyclization Strategies Towards the Synthesis of Amphidinolide Natural Products
Authors: Chatterjee Bhaskar , Mondal Dhananjoy , Bera Smritilekha 
Published: February 2023

Abstractdinoflagellates amphidinolide group of natural products have drawn the attention of the synthetic community owing to their natural scarcity, variation in ring size (12‐ to 27‐membered), and architectural complexity. The manifold strategies for creating the unique macrocyclic framework of amphidinolides, overcoming the entropy barrier of cyclisation, in good yields and selectivity, are highly encouraging as this platform provides an opportunity to develop compounds for structure‐activity relationship studies. This review emphasizes various methods of intramolecular C−C and C−O bond‐forming reactions for constructing the macrocyclic structure of different naturally occurring molecules of amphidinolide family.
A Physical Organic Approach towards Statistical Modeling of Tetrazole and Azide Decomposition**
Authors: Rein Jonas , Meinhardt Jonathan M. , Hofstra Wahlman Julie L. , Sigman Matthew S. , Lin Song 
Published: February 2023

AbstractNitrogen atom‐rich heterocycles and organic azides have found extensive use in many sectors of modern chemistry from drug discovery to energetic materials. The prediction and understanding of their energetic properties are thus key to the safe and effective application of these compounds. In this work, we disclose the use of multivariate linear regression modeling for the prediction of the decomposition temperature and impact sensitivity of structurally diverse tetrazoles and organic azides. We report a data‐driven approach for property prediction featuring a collection of quantum mechanical parameters and computational workflows. The statistical models reported herein carry predictive accuracy as well as chemical interpretability. Model validation was successfully accomplished via tetrazole test sets with parameters generated exclusively in silico. Mechanistic analysis of the statistical models indicated distinct divergent pathways of thermal and impact‐initiated decomposition.
Dynamic Hydrogen‐Bond Network as a Modulator of Bismuth–Antimony Complex Anodes for Self‐Healable and Wider Temperature Adaptive Potassium Ion Batteries
Authors: Liu Yihui , Liu Fusheng , Liu Bingbing , Xiao Yaoyao , Qin Guohui , Ma Jianmin 
Published: February 2023

AbstractAntimony (Sb)‐based anodes are attractive candidates in potassium‐ion batteries (PIBs) due to their superior capacities and rational potassium inserting voltages. However, the sluggish kinetics and poor interface compatibility severely hinder practical application. Herein, Bi0.67Sb1.33S3 nanospheres embedded into in situ formed poly(3,4‐ethylenedioxythiophene) crosslinked with polythioctic acid (PET@PTA) (Bi0.67Sb1.33S3/PET@PTA) were elaborately conceptualized with hydrogen bonds exchangeable binding (HBEB) sites. Bi0.67Sb1.33S3/PET@PTA exhibits notable self‐healing ability and wider temperature adaptability. Bi0.67Sb1.33S3/PET@PTA displays an impressive capacity of 819 mAh g−1 at 0.05 A g−1, prominent cycle ability with a 73 % capacity conservation after 500 cycles at 2 A g−1, and high capacity retention of 66 % and 84 % at −40 and 70 °C to that case at room temperature, respectively, for potassium storage. This work provides a new perspective for HBEB sites in maximizing the desirable K+ storage performance.
Engineering of core@double‐shell structured Zn@ZnO@PS particles in poly(vinylidene fluoride) composites towards significantly enhanced dielectric performances
Authors: Yao Tian , Zhou Wenying , Cao Guozheng , Peng Weiwei , Liu Jing , Dong Xinbo , Chen Xiaolong , Zhang Yanqing , Chen Yanrong , Yuan Mengxue 
Published: February 2023

AbstractPolymeric dielectrics with high dielectric permittivity (ɛ′) and low loss have momentous applications in energy storage devices. In this study, to concurrently improve the ɛ′ and restrain the loss of original Zn (Zinc)/poly(vinylidene fluoride, PVDF), the core@double‐shell structured Zn@ZnO(zinc oxide)@PS(polystyrene) particles were prepared and composited with the PVDF. The impacts of the dual shells on the dielectric properties and polarization mechanism of composites were explored by fitting the experimental data with a Havriliak–Negami (H–N) equation. The Zn@ZnO@PS/PVDF exhibit remarkably higher ɛ′ in comparison to the raw Zn and Zn@ZnO fillers owing to the induced multiple polarizations originating from the combined contributions of the α relaxation of PVDF, slow interparticle polarization and fast intraparticle polarization. More importantly, the ɛ′ of the composites remarkably increases with the PS shell’ thickness, while the loss is still kept at rather low levels owing to the PS shell’ barrier effect on long‐range charges migration. So, the introduction of the PS shell synchronously promotes both the interparticle and intraparticle polarizations in the Zn@ZnO@PS/PVDF composites toward enhanced dielectric properties. The developed strategy opens a novel path to the design and fabrication of polymer composites with desirable dielectric performances for applications in electronics and electrical industry.
Formulation of three‐dimensional, photo‐responsive printing ink: Gold nanorod‐hydrogel nanocomposites and their four‐dimensional structures that respond quickly to stimuli
Authors: Ratri Monica C. , Suh Jungwoo , Ryu Jungju , Chung Bong Geun , Shin Kwanwoo 
Published: February 2023

AbstractInterest in moving from 3D printing to 4D printing, which would enable rapid and precise motion in reaction to a given stimulus, is evolving. Thermally responsive hydrogels are one of the most common types of soft 4D devices. They are capable of changing shape or behavior autonomously in a manner resembling natural movement, and a bio‐inspired soft actuator has been fabricated by combining stimuli‐responsive nanoparticles with 3D printable hydrogels. We formulated and tested an N‐isopropylacrylamide (NIPAm) and polyethylene glycol thiol‐coated gold nanorod (P‐AuNR) hydrogel nanocomposite as an active ink material for use in the fabrication of heat‐sensitive soft actuators for photo‐responsive soft robotic motions. Due to their surface plasmon resonance (SPR), those highly dispersible P‐AuNR was able to absorb near‐infrared (NIR) light and release heat into their surroundings. This system was not immersed in water and reacted quickly and sensitively to NIR exposure. The 3D structure designed and fabricated with these inks was able to deform selectively only in a very localized part in response to non‐contact external stimuli, leading to various types of controlled shape‐morphing.
One schema to rule them all: How Schema.org models the world of search
Authors: Iliadis Andrew , Acker Amelia , Stevens Wesley , Kavakli Sezgi Başak 
Published: February 2023

AbstractSeveral industry‐specific metadata initiatives have historically facilitated structured data modeling for the web in domains such as commerce, publishing, social media, and so forth. The metadata vocabularies produced by these initiatives allow developers to “wrap” information on the web to provide machine‐readable signals for search engines, advertisers, and user‐facing content on apps and websites, thus assisting with surfacing facts about people, places, and products. A universal iteration of such a project called Schema.org started in 2011, resulting from a partnership between Google, Microsoft, Yahoo, and Yandex to collaborate on a single structured data model across domains. Yet, few studies have explored the metadata vocabulary terms in this significant web resource. What terms are included, upon what subject domains do they focus, and how does Schema.org represent knowledge in its conceptual model? This article presents findings from our extraction and analysis of the documented release history and complete hierarchy on Schema.org's developer pages. We provide a semantic network visualization of Schema.org, including an analysis of its modularity and domains, and discuss its global significance concerning fact‐checking and COVID‐19. We end by theorizing Schema.org as a gatekeeper of data on the web that authors vocabulary that everyday web users encounter in their searches.
The quintuple system 30 Arietis: Comments on orbital stability and habitability
Authors: Wittmayer Blake H. , Cuntz Manfred 
Published: February 2023

AbstractThe aim of this study is to investigate the potential of habitability for 30 Arietis, a quintuple stellar system located in the Northern Hemisphere. 30 Ari consists of two F‐type main‐sequence stars and three M dwarfs. The system is highly hierarchical; it encompasses one super‐close binary and another binary of moderate separation distance accompanied by an outside component. Significant potential for circumstellar habitability exists regarding the super‐close binary, as gauged by the size of the general habitable zone with a width of 1.85 au. Limited potential for habitability is found for the other part of the system given by 30 Ari C, but not for 30 Ari Ba+b. Hence, 30 Ari should be viewed as a system of intermediate relevance for future search missions of habitable exoplanets.
Principles for using evidence to improve biodiversity impact mitigation by business
Authors: White T. B. , Petrovan S. O. , Bennun L. A. , Butterworth T. , Christie A. P. , Downey H. , Hunter S. B. , Jobson B. R. , zu Ermgassen S. O. S. E. , Sutherland W. J. 
Published: February 2023

AbstractThere is an increasing expectation on the private sector to address biodiversity impacts and contribute towards global conservation goals. Appropriate evidence use can help businesses avoid biodiversity losses and realise gains, reduce ineffective or suboptimal action, whilst minimising biodiversity‐related risks and securing opportunities from engaging with biodiversity.We review the status of evidence‐based action in the private sector, where previous studies have identified concerning trends, and explore the barriers that may currently be hindering practice.To learn from this, and improve the status quo, we propose a set of principles for evidence‐based biodiversity impact mitigation. We outline tools and resources that can help businesses move towards evidence‐based practice and achieve each of these principles.Meeting these principles would improve the biodiversity outcomes from businesses' biodiversity related actions. However, for business action to contribute more fully to global conservation goals, broader political and socio‐economic issues also need addressing.
Holistic transfer educational learning approach for higher education
Authors: Li Hongjuan , Wang Juan , Wang Yongsheng 
Published: February 2023

AbstractTransfer training means that a person with specific knowledge or skills can turn that knowledge or ability into a real‐life scenario and adapt himself more efficiently in a formal or regulated way, such as in a classroom or a training situation. The risk factors in transfer learning include lack of flawless learning goals, practice generalizing in transferring skills, and making students learn social skills are considered essential factors. In this article, the holistic transfer educational learning approach (HTELA) has been proposed to strengthen specific instructional priorities, general practices in transferring knowledge, and socialization of learning for higher education. Knowledge transfer sharing analysis is introduced to enhance expected learning outcomes to focus on suitable material and generalizing to transfer students’ knowledge or skills from one setting to a new one. The learning visualization method was invented to promote engagement and long‐term retention in transfer learning for the higher education system. Statistics show that the suggested framework is trustworthy, with the simulation analysis obtaining an accuracy ratio of 98.2%, validation in the secured score of 95.3%, assessment of numerous learners ratio of 98.4%, error rate analysis of 23.4%, and overall performance ratio of 94.1%.
Compound heterozygosity of a de novo submicroscopic deletion and an inherited frameshift pathogenic variant in the PKHD1 gene in a fetus with bilaterally enlarged and echogenic kidneys, enlarged abdomen and oligohydramnios
Authors: Sakyu Takuya , Stover Samantha R. , Wang Yue , Ward Patricia , Gandhi Manisha , Braun Michael C. , Van den Veyver Ignatia B. , Bi Weimin 
Published: February 2023

AbstractWe present a fetus with bilaterally enlarged and echogenic kidneys. Prenatal testing detected compound heterozygosity for a 0.676 Mb de novo deletion and an inherited pathogenic variant in PKHD1. This is the first case of autosomal recessive polycystic kidney disease (ARPKD) with a prenatally detected disease‐causing PKHD1 deletion.
Optimizing the Performance of a Graphitized Carbon Xerogel as Cathode for Sodium Dual‐Ion Batteries
Authors: Caméan Ignacio , Lobato Belén , Rey‐Raap Natalia , dos Santos‐Gómez Lucía , Flores‐López Samantha , Arenillas Ana , García Ana Beatriz 
Published: February 2023

AbstractThe objective of this study is to optimize the performance of a graphitized carbon xerogel doped with graphene oxide (GXGO) as cathode for sodium dual‐ion batteries. Carbon xerogels are synthetic materials produced in large amounts, with well‐controlled chemistry, porosity and structure, by a simple and fast microwave process that has been scaled‐up. The intercalation of PF6− anions from various NaPF6 salt‐based electrolytes in a GXGO‐based cathode is investigated by considering the influence of the upper cut‐off voltage (UCOV) and of the electrolyte on the electrochemical parameters. The best results were attained in an electrolyte with a 2.0 M NaPF6 concentration in EC : EMC carbonate solvent mixture with added FEC, at a UCOV of 5.0 V. GXGO cathode provides a discharge capacity of 47 mAh g−1 after 2500 cycles with a coulombic efficiency of 97 %. Moreover, it shows great cycling stability and capacity retention of essentially 100 % after the initial cycles.
A Highly Active Cobalt Catalyst for the General and Selective Hydrogenation of Aromatic Heterocycles
Authors: Bauer Christof , Müller Felix , Keskin Sercan , Zobel Mirijam , Kempe Rhett 
Published: February 2023

AbstractNanostructured earth abundant metal catalysts that mediate important chemical reactions with high efficiency and selectivity are of great interest. This study introduces a synthesis protocol for nanostructured earth abundant metal catalysts. Three components, an inexpensive metal precursor, an easy to synthesize N/C precursor, and a porous support material undergo pyrolysis to give the catalyst material in a simple, single synthesis step. By applying this catalyst synthesis, a highly active cobalt catalyst for the general and selective hydrogenation of aromatic heterocycles could be generated. The reaction is important with regard to organic synthesis and hydrogen storage. The mild reaction conditions observed for quinolines permit the selective hydrogenation of numerous classes of N‐, O‐ and S‐heterocyclic compounds such as: quinoxalines, pyridines, pyrroles, indoles, isoquinoline, aciridine amine, phenanthroline, benzofuranes, and benzothiophenes.
Long‐term outcomes after stent implantation in very small vessel coronary artery disease
Authors: Liu En‐Shao , Yang Tse‐Hsuan , Tai Ta‐Hsin , Chiang Cheng‐Hung , Cheng Chin‐Chang , Huang Wei‐Chun , Mar Guang‐Yuan , Kuo Feng‐Yu 
Published: February 2023

AbstractBackgroundPercutaneous coronary interventions (PCI) in very small vessel lesions represent an intriguing aspect of coronary artery disease (CAD). Uncertainty still exists in stent implantation in very small caliber vessels. This study aimed to evaluate the long‐term outcomes of patients treated with 2.0‐mm drug‐eluting stent (DES).MethodThis retrospective observational study included 134 patients undergoing PCI with 2.0‐mm zotarolimus DES from December 2016 to May 2020. The primary endpoint was major adverse cardiovascular events (MACE) at 2‐year follow‐up, which was composed of all‐cause mortality, target vessel myocardial infarction, and ischemia‐driven target lesion revascularization. Multiple logistic regression analysis was used to identify the independent predictors of MACE, and odds ratios (OR) and 95% confidence intervals (CI) were calculated.ResultThe lesions were diffuse (mean length 20.9 ± 5.51 mm) and belong to type B2/C lesions (90.3%). On follow‐up, the MACE rate was 20.1% and mostly driven by late lumen loss demanding revascularization (11.9%). In multivariable analysis, chronic kidney disease (CKD) (OR: 4.291, 95% CI: 1.574−11.704, p = 0.004) and calcified lesions (OR: 3.688, 95% CI: 1.311−10.371, p = 0.013) were the independent predictors of subsequent cardiovascular events, whereas statin was associated with better outcomes (OR: 0.335, 95% CI: 0.119−0.949, p = 0.040).Conclusion2.0‐mm DES is a feasible option for treating very small vessel CAD in complex lesions. Patients with CKD and calcified lesions carry the hazard of worse outcomes, and careful consideration should be taken before stenting in this high‐risk population.