bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strengthening the Equity in Athletics Disclosure Act to Improve Gender Equity Transparency & Institutional Accountability in the Future
Authors: Staurowsky Ellen 
Published: March 2023

In 1994, the United States Congress enacted The Equity in Athletics Disclosure Act (EADA). The EADA requires colleges and universities receiving federal financial assistance to provide an annual public report on the number of athletic participation opportunities provided to men and women athletes at the varsity level and the allocation of resources and personnel made in support of those opportunities. The passage of the EADA occurred on the heels of the 20th anniversary of Title IX of the Education Amendments Act, a time marked by the realization that the vast majority of schools around the country were not in compliance with Title IX’s requirements as applied to athletic departments two decades after its passage (NCAA Staff, 1993). The purpose of the EADA when initially proposed in 1993 was to provide accessible information to stakeholders, most specifically prospective students, the public, and the U.S. Congress, that would allow interested parties to raise questions regarding the fair and equitable treatment of women athletes in the nation’s intercollegiate athletic programs. The annual report, colloquially referred to as the EADA report, is officially called The Report on Athletic Program Participation Rates and Financial Support Data. Three decades after the passage of the EADA and five decades after the passage of Title IX, there is reason to question whether the EADA has served its purpose. During Title IX’s 50th anniversary year, researchers and journalists uniformly reported a systemic failure to comply with Title IX in the area of athletics (Staurowsky et al., 2022; USA Today Staff, 2022; Wilson, 2022). Over the years, some have argued that the EADA should be eliminated (Keen, 2007), others have documented how valuable the information from the EADA is to researchers, journalists, and litigators (Tatos, 2019); others have recommended changes that would strengthen the data collection required under the EADA (Staurowsky et al, 2022); and others have argued that something akin to an EADA requirement needs to be adopted nationwide to help address sweeping gender inequities in athletics at the high school level (Green, 2008). This essay begins with an overview of the current state of Title IX compliance and gender equity in college sport, revisits the history of the EADA, provides an overview of what the EADA covers and who uses it, explores the criticisms and limitations of the EADA, and concludes with recommendations for making the EADA a more effective tool.
CT angiography in the diagnosis of acute mesenteric thrombosis: a case report
Authors: Galyautdinova L. E. , Basek I. V. , Karpova D. V. , Marukyan N. V. , Nasedkin D. B. , Borshevetskaya A.  A. , Yegorova V. S. , Lukin M. V. 
Published: March 2023

Acute mesenteric ischemia (AMI) is a rare vascular disease characterized by a high mortality rate with untimely diagnosis and treatment. The overall incidence is low, estimated at 0.09–0.2 % of all hospital admissions to emergency departments. One of the causes of acute mesenteric ischemia is acute arterial thrombosis, which is most common in the elderly.The problem of early diagnosis of acute mesenteric thrombosis is still relevant due to a non-specific clinical features. Computed tomography angiography (CT angiography) of the abdominal aorta and its branches is characterized by high sensitivity (85–98 %) and specificity (91–100 %). Computed tomography angiography is the gold standard for the diagnosis of acute mesenteric ischemia.The article discusses the use of computed tomography angiography (CT angiography) for visualization of acute mesenteric thrombosis.
Pembuatan dan Karakterisasi Nanopartikel Perak Menggunakan Ekstrak Buah Mangrove Rhizophora stylosa
Authors: Willian Nancy , Pardi Hilfi , Arief Syukri 
Published: March 2023

<p>Nanopartikel perak menampilkan sifat fisik dan biologis yang unik yang telah menarik minat penelitian karena aplikasi yang menjanjikan. Pada penelitian ini, proses fabrikasi nanopartikel perak(AgNPs) dilakukan dengan metode <em>green</em> sintesis menggunakan tanaman mangrove dengan pelarut air. Ekstrak buah mangrove <em>Rhizophora stylosa</em> (RS) pertama kali digunakan sebagai reduktor dan stabilizer dalam sintesis AgNPs. Karakteristik AgNPs ditentukan dengan spektrofotometer UV-Vis, FTIR, XRD dan TEM. Analisis spektrum UV-vis menunjukkan panjang gelombang pada 430 ‒ 445 nm. Studi FTIR mengungkapkan adanya senyawa fitokimia aktif yang bertindak sebagai zat penutup dan penstabil nanopartikel. TEM menunjukkan morfologi AgNPs yang ditemukan berbentuk bola dengan ukuran diamter sekitar 10 ‒ 60 nm. Pola XRD menunjukkan bahwa semua sampel AgNPs yang diperoleh memiliki struktur <em>face-center cubic</em> (fcc) yang menegaskan bahwa nanopartikel bersifat padatan kristalin dengan ukuran kristal 38 ‒ 77 nm. Studi ini membuktikan kemampuan biomaterial dalam sintesis AgNPs dengan mengadopsi prinsip sintesis hijau.</p><p><strong>Fabrication and Characterization of Silver Nanoparticles Using Extract of Mangrove Fruit of <em>Rhizophora stylosa</em>. </strong>Silver nanoparticles display unique physical and biological properties that have attracted research interest because of their promising applications. In this research, silver nanoparticle (AgNPs) fabrication process was carried out via green synthesis methods using mangrove plants and water as a solvent. Mangrove fruit extract <em>Rhizophora stylosa (RS)</em> was first used as a reducing agent and stabilizer in the synthesis of AgNPs. The characteristics of AgNPs were characterized using UV-Vis, FTIR, XRD, and TEM spectrophotometers. UV-vis spectrum analysis showed a peak at 430 ‒ 445 nm. FT-IR studies revealed the presence of active phytochemical compounds which act as coating agents and stabilizers for nanoparticles. TEM showed that the morphology of AgNPs was spherical with a diameter size of 10 ‒ 60 nm. The XRD patterns showed that all of the AgNPs sample obtained had a face-center cubic (fcc) structure, indicating that the nanoparticles are crystalline solids with a crystallite size of 38 ‒ 77 nm. This study proves the ability of biomaterials in the synthesis of silver nanoparticles by adopting the principle of green synthesis.</p>
Penambatan Molekuler Senyawa Aktif Sirih Merah (Piper crocatum) pada Butirilkolinesterase sebagai Kandidat Antialzheimer
Authors: Putri Rahmadi Ganesha , Safithri Mega , Husnawati Husnawati , Kurniasih Rini 
Published: March 2023

<p>Alzheimer adalah salah satu penyakit neurodegeneratif kronis dan menjadi penyakit yang sering dialami oleh orang lanjut usia. Perubahan yang terjadi dari penyakit Alzheimer, yakni penurunan fungsi kognitif, memori, dan perubahan perilaku secara permanen. Senyawa aktif pada daun sirih merah memiliki kesamaan kandungan dengan daun sirih hijau untuk menghambat butirilkolinesterase (BChE). Butirilkolinesterase adalah salah satu enzim yang berperan dalam penanganan penyakit Alzheimer dikaitkan dengan terbentuknya Alzheimer, yakni hipotesis kolinergik. Penelitian dilakukan menguji daya inhibisi senyawa aktif yang terkandung dalam daun sirih merah terhadap aktivitas butirilkolinesterase melalui pendekatan simulasi penambatan molekuler. Penelitian menggunakan dua metode, yakni penggabungan penapisan virtual dan penambatan molekuler sebagai tahapan awal pengembangan daun sirih merah terhadap aktivitas penghambatan butirilkolinesterase. Hasil dalam penelitian diperoleh, daya inhibisi terbaik ditemukan pada <em>1,2,3,4,5,6,7-heptazacycloicosane</em> sebesar 0,4888 µM dan energi bebas pengikatan sebesar -8,6 kkal∙mol<sup>-1</sup>. Residu yang berperan dalam menghambat butirilkolinesterase, yakni pada pengikatan substrat oleh ligan uji, yakni Tyr-332 dan Trp-82. Hasil penelitian ini dapat dijadikan sebagai sumber referensi dalam menemukan alternatif pengobatan penyakit Alzheimer. </p><p><strong>Molecular Docking of the Active Compound of Red Betel (<em>Piper crocatum</em>) on Butyrylcholinesterase as an Antialzheimer's Candidate. </strong>Alzheimer's is a chronic neurodegenerative disease often experienced by the elderly. Changes that occur from Alzheimer's disease such as permanent decline in cognitive function, memory, and behavioral changes. The active compounds in red betel leaves have similar contents with green betel leaves to inhibit butyrylcholinesterase (BChE). Butyrylcholinesterase is an enzyme that may play an important role in the treatment of Alzheimer's disease associated with the formation of Alzheimer's, the cholinergic hypothesis. The study tested the inhibition power of the active compounds contained in red betel leaves against the activity of butyrylcholinesterase through a molecular docking simulation approach. The method in the study used the merger of virtual screening and molecular docking as the initial stage for the development of red betel leaves against the inhibitory activity of butyrylcholinesterase. The result in the study found the best inhibitiron power was found at 1,2,3,4,5,6,7-heptazacycloicosane of 0.4888 µM and binding free energy of -8.6 kkal∙mol<sup>-1</sup>. The residues that play a role in the inhibition of butyrylcholinesterase on substrate binding by test ligands were Tyr-332 and Trp-82. The research result can be used as a reference in finding alternative treatments for Alzheimer's disease. </p>
Short-Term Neck Pain After Posterior Foraminotomy Compared with Anterior Discectomy with Fusion for Cervical Foraminal Radiculopathy
Authors: Simões de Souza Nádia F. , Broekema Anne E.H. , Soer Remko , Reneman Michiel F. , Groen Rob J.M. , van Dijk J. Marc C. , Tamási Katalin , Kuijlen Jos M.A. ,   on behalf of the FACET Investigators
Published: March 2023

Background:
Short-term neck pain after posterior cervical foraminotomy (posterior surgery) compared with anterior cervical discectomy with fusion (anterior surgery) treating cervical radiculopathy has only been assessed once, retrospectively, to our knowledge. The aim of this study was to prospectively evaluate the course of neck pain for 6 weeks after both treatments.

Methods:
This is a secondary analysis of the multicenter Foraminotomy ACDF Cost-Effectiveness Trial (FACET), conducted from January 2016 to May 2020. Of 389 patients who had single-level, 1-sided cervical radiculopathy and were screened for eligibility, 265 were randomly assigned to undergo posterior surgery (n = 132) or anterior surgery (n = 133). The primary outcome of the present analysis was neck pain, assessed weekly for 6 weeks using the visual analog scale (VAS), on a scale of 0 to 100. The secondary outcomes were arm pain, neck disability, work ability, quality of life, treatment satisfaction, motor and sensory changes, and hospital length of stay. Data were analyzed with mixed model analysis in intention-to-treat samples using 2-sided 95% confidence intervals (CIs).

Results:
In the first postoperative week, the mean VAS for neck pain was 56.2 mm (95% CI, 51.7 to 60.8 mm) after posterior surgery and 46.7 mm (95% CI, 42.2 to 51.2 mm) after anterior surgery. The mean between-group difference was 9.5 mm (95% CI, 3.3 to 15.7 mm), which gradually decreased to 2.3 mm (95% CI, −3.6 to 8.1 mm) at postoperative week 6. As of postoperative week 5, there was no significant difference between groups. Responder analyses confirmed this result. Secondary outcomes showed small differences between groups.

Conclusions:
Insight into the course of neck pain during the first 6 weeks after posterior compared with anterior surgery is provided. Despite initially more neck pain after posterior surgery, patients swiftly improved and, as of postoperative week 5, results similar to those after anterior surgery were observed. Our findings should enable improved patient counseling and enhanced shared decision-making between physicians and patients with cervical radiculopathy, where more neck pain in the first postoperative weeks should be balanced against the benefits of posterior surgery.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
COVID-19 Induced Acute Respiratory Distress Syndrome; A systematic Review and Meta-Analysis
Authors: Azagew Abere Woretaw , Beko Zerko Wako , Ferede Yohannes Mulu , Mekonnen Habtamu Sewunet , Abate Hailemichael Kindie , Mekonnen Chilot Kassa 
Published: March 2023

Abstract
Introduction

Acute Respiratory Distress Syndrome (ARDS) is a potentially fatal form of respiratory failure among COVID-19 patients. Globally, there are inconsistent findings regarding acute respiratory distress syndrome among COVID-19 patients. Therefore, the aim of this study is to estimate the pooled prevalence of acute respiratory syndrome among COVID-19 patients

Methods

We have accessed previous studies through an electronic web-based search strategy using PubMed, Google, Google Scholar, and Cochrane Library with a combination of search terms. The quality of each included article was assessed using the Newcastle Ottawa assessment Scale for cross-sectional studies. All statistical analyses were done using STATA version 14 Software for Windows, and meta-analysis was carried out using a random effect model. Heterogeneity was assessed using Cochrane Q statistics and I-Square (I2), and the publication bias was detected based on the graphic asymmetry of funnel plot and/or Egger’s test.

Results

Out of 645 studies screened, 11 studies with 2845 participants fulfilled the inclusion criteria and were included in the proportion estimation. The overall pooled prevalence of ARDS was found to be 32.2%(95% CI = 27.70%-41.73%). The heterogeneity test (I2) of the study was 97.3% with p value < 0.001. The study indicates there is a considerable variability across the studies. Subgroup analysis and meta-regression were computed to detect the effect of variation. Furthermore, the publication bias was evaluated then after the trim and fill analysis was conducted.

Conclusion

The pooled prevalence of COVID-19 induced acute respiratory distress syndrome was found to be high, which needs a global effort to combat its morbidity and mortality. Therefore, both the governmental and non-governmental organizations better give emphasis on COVID-19 prevention.
Graphs with convex balls
Authors: Chalopin Jérémie , Chepoi Victor , Giocanti Ugo 
Published: March 2023

Abstract
In this paper, we investigate the graphs in which all balls are convex and the groups acting on them geometrically (which we call CB-graphs and CB-groups).These graphs have been introduced andcharacterized by Soltan and Chepoi (1983) and Farber and Jamison (1987). CB-graphs and CB-groups generalize systolic (alias bridged) and weakly systolic graphs and groups,which play an important role in geometric group theory. We present metric and local-to-global characterizations of CB-graphs. Namely, we characterize CB-graphs G as graphs whose triangle-pentagonal complexes are simply connected and balls of radius at most 3 are convex. Similarly to systolic and weakly systolic graphs, we provea dismantlability result for CB-graphs G: we show that their squares G^2 are dismantlable. This implies that the Rips complexes of CB-graphsare contractible. Finally, we adapt and extend the approach of Januszkiewicz and Swiatkowski (2006) for systolic groups and of Chalopin et al. (2020) for Helly groups, to show that the CB-groups are biautomatic.
Characterizing provider-led adaptations to mobile phone delivery of the Adolescent Transition Package (ATP) in Kenya Using the Framework for Reporting Adaptations and Modifications to Evidence-based Implementation Strategies (FRAME-IS): a mixed methods approach
Authors: Mangale Dorothy Imbuka , Onyango Alvin , Mugo Cyrus , Mburu Caren , Chhun Nok , Wamalwa Dalton , Njuguna Irene , Means Arianna Rubin , John-Stewart Grace , Weiner Bryan J. , Beima-Sofie Kristin 
Published: March 2023

Abstract
Background: The COVID-19 pandemic resulted in disruptions to routine HIV services for youth living with HIV (YLH), provoking rapid adaptation to mitigate interruptions in care. The Adolescent Transition to Adult Care for HIV-infected Adolescents (ATTACH) study (NCT03574129) was a hybrid I cluster randomized trial testing the effectiveness of a healthcare worker-delivered disclosure and transition intervention – the Adolescent Transition Package (ATP). During the pandemic, HCWs leveraged phone delivery of the ATP and were supported to make adaptations. We characterized real-time, provider-driven adaptations made to support phone delivery of the ATP.
Methods: We conducted continuous quality improvement (CQI) meetings with healthcare workers (HCWs) involved in phone delivery of the ATP at 10 intervention sites. CQI meetings used plan-do-study-act (PDSA) cycles and were audio-recorded. Adaptations were coded by two-independent coders using the Framework for Reporting Adaptations and Modifications to Evidence-based Implementation Strategies (FRAME-IS). Adaptation testing outcomes (adopt, retest or abandon) and provider experience implementing the adaptations were also recorded. We summarized adaptation characteristics, provider experience and outcomes.
Results: We identified 72 adaptations, 32 were unique. Overall, adaptations included modification to context (53%, n=38), content (49%, n=35), and evaluation processes (13%, n=9). Context adaptations primarily featured changes to personnel, format and setting, while content and evaluation adaptations were frequently achieved by simple additions, repetition, and tailoring/refining of the phone delivery strategy. Nine adaptations involved abandoning, then returning to phone delivery. HCWs sought to increase reach, improve fidelity, and intervention fit within their context. Most adaptations (96%, n=69) were perceived to increase the feasibility of phone delivery when compared to before the changes were introduced, and HCWs felt 83% (n=60) of adaptations made phone delivery easier. Most adaptations were either incorporated into routine workflows (47%) or tested again (47%).
Conclusion: Adaptation of phone delivery was a feasible and effective way of addressing challenges with continuity of care for YLH during the COVID-19 pandemic. Adaptations were primarily context adaptions. While FRAME-IS was apt for characterizing adaptations, more use cases are needed to explore the range of its utility. Incorporating for a strategy for tracking outcomes within FRAME-IS may further our understanding of how adaptations influence implementation.
Trial Registration: Trial registered on clinicaltrial.gov as NCT03574129.
Increasing and Decreasing Soft RoughSet Approximations
Authors: El-Sheikh S. A. , Kandil S. A. , Hussien S. 
Published: March 2023

Abstract
The paper presents a novel method for generating increasing and decreasing soft rough set approximations that addresses limitations of a previous approach by Shawkat et al. [3], which su ered from issues such as the modi ed soft lower approximation not being equal to the universe set and the modi ed soft upper approximation being empty. The proposed method is described through propositions and examples and can be applied to both qualitative and quantitative real-world problems. It is compared to the classical soft rough set model and aims to improve accuracy by converting partial ordered relations to linear ordered relations, such as directed or total directed relations, where every subset becomes crisp. The concepts and results are illustrated through examples. Overall, the new method o ers a generic solution that addresses the shortcomings of the previous approach and can improve the accuracy of soft rough set approximations in various domains.
Mathematics Subject Classi cation (2020): 03C55, 03E04, 54G20 and 92C50.
Identifying Key Genes for Diabetic Kidney Disease by Bioinformatics Analysis
Authors: Xu Yushan , Li Lan , Tang Ping , Zhang Jingrong , Zhong Ruxian , Luo Jingmei , Lin Jie , Zhang Lihua 
Published: March 2023

Abstract
Background
There are no reliable molecular targets for early diagnosis and effective treatment in the clinical management of diabetic kidney disease (DKD). To identify novel gene factors underlying the progression of DKD.
Methods
The public transcriptomic datasets of the alloxan-induced DKD model and the streptozotocin-induced DKD model were retrieved to perform an integrative bioinformatic analysis of differentially expressed genes (DEGs) shared by two experimental animal models. The dominant biological processes and pathways associated with DEGs were identified through enrichment analysis. The expression changes of the key DEGs were validated in the classic db/db DKD mouse model.
Results
The downregulated and upregulated genes in DKD models were uncovered from GSE139317 and GSE131221 microarray datasets. Enrichment analysis revealed that metabolic process, extracellular exosomes, and hydrolase activity are shared biological processes and molecular activity is altered in the DEGs. Importantly, Hmgcs2, angptl4, and Slco1a1 displayed a consistent expression pattern across the two DKD models. In the classic db/db DKD mice, Hmgcs2 and angptl4 were also found to be upregulated while Slco1a1 was downregulated in comparison to the control animals.
Conclusions
In summary, we identified the common biological processes and molecular activity being altered in two DKD experimental models, as well as the novel gene factors (Hmgcs2, Angptl4, and Slco1a1) which may be implicated in DKD. Future works are warranted to decipher the biological role of these genes in the pathogenesis of DKD.
Effect of Behavioural Model-Guided Nutritional Counselling on Old Age People’s Nutritional Status: A Quasi-Experimental Study Design
Authors: Muhye Ahmed , Fentahun Netsanet 
Published: March 2023

Abstract

Background: Physiological, pathological, and socioeconomic changes occur in older people that could influence their dietary intake, efficiency of nutrient utilization, and nutritional status. Impaired nutritional status aggravates existing disease conditions and worsens their health problems. Appropriate nutrition assessment followed by timely intervention and regular follow-up improves the nutritional status and health outcomes of older people, which are lacking in Ethiopia. Therefore, this study was aimed to estimate the effect of behavioural model-guided nutritional counselling on older people’s nutritional status in Bahir Dar City, Northwest Ethiopia.
Methods: A single-group pretest-posttest quasi-experimental design was conducted on 293 community-dwelling older adults aged 60 and above from January 28 to May 26, 2022. Trained nurses provided nutritional counseling guided by the health belief model and the theory of the behavioural model. The intervention was through home-to-home visits once a week for one month, with a two-month follow-up. Nutritional status, nutritional knowledge, dietary intake, body weight, and body mass index were measured. All measurements were recorded on a pre-post schedule, and the changes in outcomes were measured using a paired T-test.
Results: About 34(12.5%) and 21(9.6%) of the study participants were malnourished, while only 87(32.1%) and 76 (34.7%) were normal before and after the intervention, respectively. The mean score of nutritional status significantly increased from 21.55 ± 3.72 before the nutritional intervention to 21.64 ± 4.12 after the intervention (x̄ = -0.30, t218 = -2.72, 95% CI: -0.52- (-0.83), p = 0.007). While, mean body weight and the body mass index did not change after the intervention’s adoption.
The mean nutrition knowledge score rose from 7.58 ± 1.05 to 11.61 ± 1.37 (x̄ = 3.98, t218 = -32.79, 95% CI: -4.21-(-3.73), p < 0.001). Furthermore, the consumption of dairy products, fruits, and meat or egg intake increased after the intervention (p < 0.001).
Conclusion: Behavioural model-guided nutritional counseling improved the nutritional status of community-dwelling older people. A participant-centered nutritional programme recommended improving the health of community-dwelling older people.
Trial Registration: Clinical Trial Registration-URL: www.clinicaltrials.gov, identifier number: NCT04746664, first released 10/02/2021.