bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human‐ and AI‐based authorship: Principles and ethics
Authors: Teixeira da Silva Jaime A. , Tsigaris Panagiotis 
Published: June 2023

Key points
The International Committee of Medical Journal Editors (ICMJE) recommendations for authorship are the dominant guidelines that guide who, and under what circumstances, an individual can be an author of an academic paper.
Large language models (LLMs) and AI, like ChatGPT, given their ability and versatility, pose a challenge to the human‐based authorship model.
Several journals and publishers have already prohibited the assignment of authorship to AI, LLMs, and even ChatGPT, not recognizing them as valid authors.
We debate this premise, and asked ChatGPT to opine on this issue. ChatGPT considers itself as an invalid author.
We applied the CRediT criteria to AI, finding that it was definitively able to satisfy three out of the 14 criteria, but only in terms of assistance. This was validated by ChatGPT itself.
Recent Advances in Dual‐Function Superhydrophobic Antibacterial Surfaces
Authors: Jia Dongxu , Lin Yuancheng , Zou Yi , Zhang Yanxia , Yu Qian 
Published: June 2023

AbstractBacterial adhesion and subsequent biofilm formation on the surfaces of synthetic materials imposes a significant burden in various fields, which can lead to infections in patients or reduce the service life of industrial devices. Therefore, there is increasing interest in imbuing surfaces with antibacterial properties. Bioinspired superhydrophobic surfaces with high water contact angles (>150°) exhibit excellent surface repellency against contaminations, thereby preventing initial bacterial adhesion and inhibiting biofilm formation. However, conventional superhydrophobic surfaces typically lack long‐term durability and are incapable of achieving persistent efficacy against bacterial adhesion. To overcome these limitations, in recent decades, dual‐function superhydrophobic antibacterial surfaces with both bacteria‐repelling and bacteria‐killing properties have been developed by introducing bactericidal components. These surfaces have demonstrated improved long‐term antibacterial performance in addressing the issues associated with surface‐attached bacteria. This review summarizes the recent advancements of these dual‐function superhydrophobic antibacterial surfaces. First, a brief overview of the fabrication strategies and bacteria‐repelling mechanism of superhydrophobic surfaces is provided and then the dual‐function superhydrophobic antibacterial surfaces are classified into three types based on the bacteria‐killing mechanism: i) mechanotherapy, ii) chemotherapy, and iii) phototherapy. Finally, the limitations and challenges of current research are discussed and future perspectives in this promising area are proposed.
Effect of the Fiber Diameter of Polyamide 11 Nanofibers on Their Internal Molecular Orientation and Properties
Authors: Yang Zichen , Takarada Wataru , Matsumoto Hidetoshi 
Published: June 2023

AbstractHerein, the effect of the diameter of polyamide 11 nanofibers (PA11 NFs) on their internal structures as well as thermal and mechanical properties is investigated. Aligned PA11 NFs with diameters ranging from 109 to 462 nm are prepared by the single‐component solvent electrospinning of different PA11/1,1,1,3,3,3‐hexafluoro‐2‐propanol (HFIP) solutions (4–8 wt%) and subsequently characterized. Owing to the similar hydrogen bond formation within the NFs during electrospinning, all prepared NFs have δ'‐phase crystals with similar crystallinities and crystallite sizes. However, the orientation of the δ'‐phase crystals is disrupted in NFs with diameters less than 200 nm, due to the rapid solidification during electrospinning. The δ'‐phase crystals are the most highly oriented within NFs having a fiber diameter of ≈300 nm, and the corresponding NF sheets exhibit the highest mechanical strength. A single PA11 NF with a fiber diameter of ≈300 nm also exhibits a good piezoelectric response (piezoelectric coefficient d33 = 2.1 pm V–1).
Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells
Authors: Kim Su‐Hyeong , Hahm Eun‐Ryeong , Singh Shivendra V. 
Published: June 2023

AbstractForkhead Box Q1 (FoxQ1) transcription factor is overexpressed in luminal‐type and basal‐type human breast cancers when compared to normal mammary tissue. This transcription factor is best known for its role in promotion of breast cancer stem‐like cells and epithelial to mesenchymal transition. The present study documents a novel function of FoxQ1 in breast cancer cells. Overexpression of FoxQ1 in basal‐like SUM159 cells and luminal‐type MCF‐7 cells resulted in increased conversion of microtubule‐associated protein light chain 3 beta‐I (LC3B‐I) to LC3B‐II, which is a hallmark of autophagy. Autophagy induction by FoxQ1 overexpression was confirmed by visualization of LC3B puncta as well as by transmission electron microscopy. Expression profiling for genes implicated in autophagy regulation revealed upregulation of many genes, including ATG4B, ATG16L1, CTSS, CXCR4 and so forth but downregulation of BCL2L1, DRAM1, TNF, ULK2 and so forth by FoxQ1 overexpression in SUM159 cells. Western blot analysis confirmed upregulation of ATG4B and CXCR4 proteins by FoxQ1 overexpression in both SUM159 and MCF‐7 cells. Chromatin immunoprecipitation assay revealed recruitment of FoxQ1 at the promoter of ATG4B. Pharmacological inhibition of ATG4B using S130 significantly increased apoptosis induction by DOX in empty vector transfected as well as FoxQ1 overexpressing SUM159 and MCF‐7 cells but this effect was statistically significantly lowered by FoxQ1 overexpression indicating the protective role of FoxQ1 on apoptosis. Treatment of SUM159 cells with S130 and DOX enhanced LC3B‐II level in both empty vector transfected cells and FoxQ1 overexpressing SUM159 cells but not in FoxQ1 overexpressing MCF‐7 cells. In conclusion, FoxQ1 is a novel regulator of autophagy.
Gasdermin E plasmid DNA/indocyanine green coloaded hybrid nanoparticles with spatiotemporal controllability to induce pyroptosis for colon cancer treatment
Authors: Jiang Ailing , Wang Mao , Liu Huimin , Liu Simeng , Song Xiaoshuang , Zou Yu , Deng Yuchuan , Qin Qin , Song Yiran , Zheng Yu 
Published: June 2023

AbstractPyroptosis is an immunogenic cell death and would trigger robust antitumor immunity. However, due to cytoxicity of pyroptosis executors, Gasdermin family proteins, it is indispensable to construct tumor‐specific vectors. Here, we report the development of a novel vector named lipid‐coated poly(lactide‐co‐glycolide) (PLGA) nanoparticles coloaded with Gasdermin E expressing plasmid DNA (GSDME‐pDNA) with a heat‐inducible mouse heat shock protein 70 (mHSP70) as the promoter and a photosensitizer indocyanine green (ICG) to activate the mHSP70 element. The cellular internalization and transfection rate of the vector were remarkably enhanced by photothermal treatment. And the mHSP70 promoter further improved the gene transfection rate for about 15‐fold. With the combination of oxaliplatin (OXA), the mechanism switch between apoptosis and pyroptosis was fulfilled by cleavage of GSDME through activated caspase‐3, which promoted damage‐associated molecular patterns (DAMPs) release and increased the infiltration of immune cells at the tumor site. This combination strategy not only prominently inhibited the growth of the treated tumor, but also exhibited a lethal effect on the distal tumors. Besides, mouse colon cancer cell CT26 overexpressing GSDME after OXA treatment had the potential to be the preventive tumor vaccine. This study provides a novel thought and feasible method for the clinical treatment of colon cancer.
Mechanical and thermal characteristics of steam‐exploded silane grafted Kigelia Pinnata fruit (KPF) fiber reinforced vinyl ester polymer composites
Authors: K Vishal , K Rajkumar , P Sabarinathan , A Arun 
Published: June 2023

AbstractThe cellulose‐rich Kigelia pinnata aqueous fruit (KPF) fiber is a valuable natural biomass and has drawn attention as a renewable resource. Vinyl ester polymer matrix composites with better interfacial properties can have higher mechanical and energy dissipation properties. It can be obtained by the use of steam‐exploded silane‐grafted KP fibers with various fractions incorporated in the polymer matrix. KPF fiber grafting was maximized at 5% concentration after a steam explosion, removing hemicelluloses and lignin, thereby enriching a 23% crystallinity index (CI), leading to rich cellulose fiber. Steam explosion along with silane grafting increases the interfacial adhesion of the KPF fibers and the matrix through the interfacial bonding structure of Si–O–Si bonds, as confirmed by FTIR. A fiber with greater tensile strength was used to fabricate the vinyl ester composites. The highest tensile value of the steam‐exploded silane surface‐modified 30% KPF fiber‐reinforced composite was 125 MPa compared to the unmodified one due to increased stress distribution and restricted polymer chain movements. Compared to the untreated 30% KPF fruit fiber composite, steam‐exploded silane‐treated fiber showed a 12% higher impact energy due to faster load transfer, causing more impact energy absorption. A relatively higher interlaminar shear strength was shown for 30% treated KPF composites than for 30% untreated KPF composites. The steam‐exploded silane‐treated fiber (30%) composite shows the greatest thermal decomposition temperature of 399 °C because silane‐surface‐treated fibers contact the organo‐functional silane group in the polymer matrix. As a result, it obstructs polymer chain motions at higher temperatures, causing increased bonding strength.
Fabrication of the low‐residual‐stress optical microstructure by using the simulation and practice strategies, in‐mold induction heating system, and injection compression molding technology
Authors: Huang Zhi‐Yu , Chiu Chun‐Yang , Ke Kun‐Cheng , Yang Sen‐Yeu 
Published: June 2023

AbstractThis study developed an in‐mold induction heating system for the injection compression molding process to overcome the problem of incomplete filling of microstructures caused by the formation of skin layers and residual stress caused by flow. Moldex3D software was used with the Taguchi method to optimize the molding parameters for both injection molding and injection compression molding, with the aim of reducing warpage and improving optical quality. The in‐mold induction heating system has extremely high heating efficiency. Experiments revealed that a time of only 8 s was required to inducted‐heat up the core to the glass transition temperature which keeps the melt under a good state of flow and allows a replication rate of 97%. In addition, the ICM process can effectively reduce the flow‐induced residual stress and improve the optical properties of the obtained samples. Finally, the illuminance of the product fabricated through ICM with induction heating for 10 s was 2.3 times higher than that of the product obtained through ICM without induction heating. Accordingly, the proposed induction heating system is feasible for use in ICM the rapid manufacturing of high‐quality optical products with microstructures.
Physical therapist–led interventions based on the biopsychosocial model provide improvement in disability and pain for spinal disorders: A systematic review and meta‐analysis
Authors: Miki Takahiro , Kondo Yu , Kurakata Hiroshi , Takebayashi Tsuneo , Samukawa Mina 
Published: June 2023

AbstractObjectiveTo summarize the effects of physical therapist–led interventions based on the biopsychosocial (BPS) model in spinal disorders compared to interventions with no BPS model through a systematic review and meta‐analysis of randomized‐controlled trials.TypeSystematic review and meta‐analysis.Literature SurveyWe searched the Web of Science, CENTRAL, MEDLINE, PsycINFO, CINAHL, and PEDro up to October 27, 2022.MethodologyPain intensity and disability were primary outcomes and psychological factors were secondary outcomes in spinal disorders. The included intervention was physical therapist–led interventions based on the BPS model. The control group received no physiotherapy intervention for BPS. Pooled effects were analyzed as standardized mean differences (SMDs) and 95% confidence intervals (CIs), and the random‐effects model was used for the meta‐analysis. The subgroup analysis was divided into low back pain group and neck pain group. Another subgroup analysis was conducted only of the groups that had received training of the BPS model.SynthesisFifty‐seven studies with 5471 participants met the inclusion criteria. For pain intensity, there was a statistically significant effect for the BPS model led by physical therapists in the short, medium, and long terms. The SMDs with 95% CIs were −0.44 (−0.62, −0.27), −0.24 (−0.37, −0.12), and −0.17 (−0.28, −0.06), respectively. Outcomes were clinically significant, except in the long term. For disability, there was a statistically significant effect in the short, medium, and long terms. The SMDs with 95% CIs were −0.48 (−0.69, −0.27), −0.44 (−0.64, −0.25), and −0.37 (−0.58, −0.15), respectively. All periods were clinically significant. The quality of the evidence was low for all of the main outcomes for all of the terms.ConclusionPhysical therapist–led interventions based on the BPS model effectively improve pain intensity and disability in patients with spinal disorders based on low‐quality evidence.
Lung ultrasound score predicts patent ductus arteriosus ligation among neonates ≤25 weeks
Authors: Zong Haifeng , Huang Yichu , Huang Zhifeng , Zhao Jie , Lin Bingchun , Fu Yongping , Lin Yanqing , Yu Yanliang , Sun Hongyan , Yang Chuanzhong 
Published: June 2023

AbstractBackgroundThis prospective study aimed to investigate whether lung ultrasound score (LUSs) can predict the patent ductus arteriosus (PDA) ligation.MethodsPreterm infants ≤25 weeks of gestational age (GA) were enrolled. A lung ultrasound was performed on the 14th day of life. Each lung zone was given a score between 0 and 4. A receiver‐operating characteristic (ROC) curve was constructed to evaluate the ability of the LUSs for predicting ligation.ResultsA total of 81 infants were eligible with a median GA and birth weight (BW) of 25 weeks (24.1–25.2) and 710 g (645–770), respectively. The median time from birth to ligation was 35 days (32–51). Those who underwent ligation had a longer time of mechanical ventilation (34 [26–39] vs. 19 [12–30], p < 0.001), shorter time of noninvasive respiratory support (39 [32–51] vs. 50 [41.5–57], p < 0.01), higher incidence of the bronchopulmonary dysplasia (BPD) (p < 0.01), and severe BPD (p < 0.001). The LUSs had an area under the ROC of 0.96 (95% confidence interval: 0.93–0.99) for the prediction of ligation. A LUSs cutoff of 36 has a sensitivity and specificity of 96% and 86% and positive and negative predictive values of 82% and 98%, respectively.ConclusionsLUSs at an early stage of life can predict PDA ligation in extremely preterm infants. It would be helpful to reduce morbidity by reducing the duration and magnitude of respiratory support.
Achieving Stable Lithium Metal Anode at 50 mA cm−2 Current Density by LiCl Enriched SEI
Authors: Fan Yuxin , Wu Tongwei , He Miao , Chen Wei , Yan Chaoyi , Li Fei , Hu Anjun , Li Yaoyao , Wang Fan , Jiao Yu , Zhou Mingjie , Wang Shuying , Hu Yin , Yan Yichao , Lei Tianyu , Wang Xianfu , Xiong Jie 
Published: June 2023

AbstractLithium metal batteries are intensively studied due to the potential to bring up breakthroughs in high energy density devices. However, the inevitable growth of dendrites will cause the rapid failure of battery especially under high current density. Herein, the utilization of tetrachloroethylene (C2Cl4) is reported as the electrolyte additive to induce the formation of the LiCl‐rich solid electrolyte interphase (SEI). Because of the lower Li ion diffusion barrier of LiCl, such SEI layer can supply sufficient pathway for rapid Li ion transport, alleviate the concentration polarization at the interface and inhibit the growth of Li dendrites. Meanwhile, the C2Cl4 can be continuously replenished during the cycle to ensure the stability of the SEI layer. With the aid of C2Cl4‐based electrolyte, the Li metal electrodes can maintain stable for >300 h under high current density of 50 mA cm−2 with areal capacity of 5 mAh cm−2, broadening the compatibility of lithium metal anode toward practical application scenarios.
Pseudocapacitive Potassium‐Ion Intercalation Enabled by Topologically Defective Soft Carbon toward High‐Rate, Large‐Areal‐Capacity, and Low‐Temperature Potassium‐Ion Batteries
Authors: Yang Haozhen , Huang Junlong , Liu Shaohong , Chen Yongqi , Cen Zongheng , Shi Chenguang , Lu Yuheng , Fu Ruowen 
Published: June 2023

AbstractCarbonaceous materials are widely investigated as anodes for potassium‐ion batteries (PIBs). However, the inferior rate capability, low areal capacity, and limited working temperature caused by sluggish K‐ions diffusion kinetics are still primary challenges for carbon‐based anodes. Herein, a simple temperature‐programmed co‐pyrolysis strategy is proposed for the efficient synthesis of topologically defective soft carbon (TDSC) based on inexpensive pitch and melamine. The skeletons of TDSC are optimized with shortened graphite‐like microcrystals, enlarged interlayer spacing, and abundant topological defects (e.g., pentagons, heptagons, and octagons), which endow TDSC with fast pseudocapacitive K‐ion intercalation behavior. Meanwhile, micrometer‐sized structure can reduce the electrolyte degradation over particle surface and avoid unnecessary voids, ensuring a high initial Coulombic efficiency as well as high energy density. These synergistic structural advantages contribute to excellent rate capability (116 mA h g−1 at 20 C), impressive areal capacity (1.83 mA h cm−2 with a mass loading of 8.32 mg cm−2), long‐term cycling stability (capacity retention of 91.8% after 1200 h cycling), and low working temperature (−10 °C) of TDSC anodes, demonstrating great potential for the practical application of PIBs.
Impact of slag‐fly ash cementitious system on thermal controls and durability of high‐strength mass concrete
Authors: Mokal Manish Prabhakar , Mandal Romio , Nayak Sanket , Panda Sarat Kumar 
Published: June 2023

AbstractThe rise in temperature due to the heat of hydration in the high‐strength mass concrete poses serious issues such as thermal cracking and delayed ettringite formation. The present experimental investigation is to optimize the proportions of SCMs like fly ash (FA) and ground granulated blast‐furnace slag (GGBS) for the same grade of high‐strength mass concrete with a focus on controlling the peak temperature rise and improving sustainability. For this purpose, one 100% ordinary Portland cement (OPC)‐based sample (T1) and five SCMs‐based samples viz. T2, T3, T4, T5, and T6 in which OPC was replaced by 20% FA, 35% FA, 50% GGBS, 70% GGBS, and 33%FA + 33% GGBS, respectively, were cast in the insulated blocks having one cubic meter volume. Analyzing critically, it is observed that for the same grade of concrete, the right blend of SCMs greatly reduces the peak core temperature (~33.2% and ~ 39.4% for T5 and T6 samples, respectively) than the sample prepared with 100% OPC. This is due to the reduction in the total heat of hydration in the SCMs‐based system than that of the OPC‐based system at early age. The amount of hydration products formed at early age varies for different percentages of SCMs, which is investigated by X‐ray diffraction (XRD), Fourier‐transform infrared spectroscopy (FTIR), and Field emission scanning electron microscopy (FESEM) analyses. Additionally, compressive strength analysis reveals that all the samples achieved almost similar strength (71.4, 74.6, 73.5, 71.5, 69.2, and 68.2 MPa, respectively, for T1 to T6 samples) at 56 days. Moreover, the rapid chloride permeability test (RCPT) values of the T2 to T5 samples are measured to be 597, 461, 672, 584, and 621 coulombs; while, the same is measured to be 2637, coulombs for the T1 sample, indicating higher durability of SCMs‐based samples. Finally, based on the analyses, a plausible model has been presented to explain the phenomenon, and industrial viability analysis is done to adjudge its suitability for an onsite application.
Understanding the Rhodopsin Worldview Through Atomic Force Microscopy (AFM): Structure, Stability, and Activity Studies
Authors: Senapati Subhadip , Park Paul S.‐H. 
Published: June 2023

AbstractRhodopsin is a G protein‐coupled receptor (GPCR) present in the rod outer segment (ROS) of photoreceptor cells that initiates the phototransduction cascade required for scotopic vision. Due to the remarkable advancements in technological tools, the chemistry of rhodopsin has begun to unravel especially over the past few decades, but mostly at the ensemble scale. Atomic force microscopy (AFM) is a tool capable of providing critical information from a single‐molecule point of view. In this regard, to bolster our understanding of rhodopsin at the nanoscale level, AFM‐based imaging, force spectroscopy, and nano‐indentation techniques were employed on ROS disc membranes containing rhodopsin, isolated from vertebrate species both in normal and diseased states. These AFM studies on samples from native retinal tissue have provided fundamental insights into the structure and function of rhodopsin under normal and dysfunctional states. We review here the findings from these AFM studies that provide important insights on the supramolecular organization of rhodopsin within the membrane and factors that contribute to this organization, the molecular interactions stabilizing the structure of the receptor and factors that can modify those interactions, and the mechanism underlying constitutive activity in the receptor that can cause disease.