bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clay minerals and other hydrous alteration products in the Kaba meteorite: Review of the literature and new XRD investigations
Authors: Viczián István , Kristály Ferenc 
Published: February 2023

Abstract
The present study is a review of publications regarding special aspects of the mineralogy of the Kaba meteorite, clay minerals, hydrous phases, and organic matter. In Section 1, the history of fall and finding of the meteorite and the first classical mineralogical description in the Year 1961 are mentioned. The most frequent alteration product of primary silicates and the glassy matrix is Fe-bearing saponite. By modelling of hydrothermal alteration of Allende-type meteorites, artificial saponite could be produced. The thermodynamic study proved the possibility of hydrous neoformation of silicates and magnetite at low temperatures, mostly below 100°C. The formation of Fe-rich external rims in forsterite grains by hydrothermal action was demonstrated by electron probe microanalysis and scanning electron microscopy-cathodo-luminescence methods. Foliation in CV3 carbonaceous chondrites indicates that the Kaba meteorite is derived from the external, shallow zone of the parent body. A combination of X-ray power diffraction (XRD) and Mössbauer spectroscopy made the exact modal analysis of CV3 chondrites possible, including Kaba. The study of alteration by in situ determination of stable oxygen isotope contents may provide constraints regarding the oxygen isotopic composition of the aqueous fluid on the CV parent asteroid. The degree of thermal metamorphism of the organic matter was determined by using Raman spectroscopy. The presence of aromatic and aliphatic, saturated and unsaturated hydrocarbons, and various amino acids was demonstrated. The non-biogenic origin is more probable; however, there are textural and mineralogical observations that may indicate also the biogenic origin of organic matter. In addition to the review of the literature above, as an appendix, shortly new XRD investigations of the authors are reported that indicated smectite-like phases in a thin section made of the meteorite.
Testing for explosive bubbles: a review
Authors: Skrobotov Anton 
Published: February 2023

Abstract
This review discusses methods of testing for explosive bubbles in time series. A large number of recently developed testing methods under various assumptions about innovation of errors are covered. The review also considers the methods for dating explosive (bubble) regimes. Special attention is devoted to time-varying volatility in the errors. Moreover, the modelling of possible relationships between time series with explosive regimes is discussed.
Ukrainians in French Holocaust Literature: Piotr Rawicz’sBlood from the Skyand Jonathan Littell’sThe Kindly Ones
Authors: Duffy Helena 
Published: February 2023

AbstractThis article compares and contrasts the representational strategies used by Piotr Rawicz and Jonathan Littell in their Holocaust novels. Separated by 40 years,Le Sang du ciel(1961) (Blood from the Sky) andLes Bienveillantes(2006) (The Kindly Ones) differ in terms of structure, style, and point of view. The article examines the import of these strategies for the way Rawicz’s and Littell’s narratives portray Ukrainians. Its main contention is that, while casting Ukrainians primarily as complicitous in the Holocaust, the two novels frame their complicity with Ukraine’s wartime hopes for sovereignty which it hoped to achieve through collaboration with Hitler’s Germany. By foregrounding Ukraine’s protracted statelessness, oppression by Russia (and later the Soviet Union), and exploitation by Polish landowning gentry, the two novels succeed at offering a nuanced view of Ukrainians without, however, redeeming them.
Analysis of hygrothermal recovery of tension wood induced by boiling at 50–80 °C
Authors: Matsuo-Ueda Miyuki , Yoshida Masato , Yamamoto Hiroyuki 
Published: February 2023

Abstract
Hygrothermal recovery (HTR) is an irreversible dimensional change that occurs when green wood is heated under wet conditions. Reaction wood presents a substantial dimensional change owing to HTR. In this study, the HTR of reaction wood was examined to understand the mechanisms of HTR. This study aimed to elucidate the HTR of tension wood, and particularly its temperature dependency. Two types of analyses were applied to the data measured, namely the two-phase exponential model and the time-temperature superposition analysis. The two-phase model was well fitted to the data and showed that the evolution of HTR could be divided into initial recovery and subsequent continuum contraction. The intensity of the initial recovery increased with increasing temperature. Continuum contraction was not well characterized in this study. Time–temperature superposition analysis provided an apparent activation energy of 326 kJ/mol, which suggests that HTR is a lignin-related phenomenon. A simulation based on the analysis also simulated HTR behavior at ambient temperature in a standing tree.
Structural color generation: from layered thin films to optical metasurfaces
Authors: Wang Danyan , Liu Zeyang , Wang Haozhu , Li Moxin , Guo L. Jay , Zhang Cheng 
Published: February 2023

AbstractRecent years have witnessed a rapid development in the field of structural coloration, colors generated from the interaction of nanostructures with light. Compared to conventional color generation based on pigments and dyes, structural color generation exhibits unique advantages in terms of spatial resolution, operational stability, environmental friendliness, and multiple functionality. Here, we discuss recent development in structural coloration based on layered thin films and optical metasurfaces. This review first presents fundamentals of color science and introduces a few popular color spaces used for color evaluation. Then, it elaborates on representative physical mechanisms for structural color generation, including Fabry–Pérot resonance, photonic crystal resonance, guided mode resonance, plasmon resonance, and Mie resonance. Optimization methods for efficient structure parameter searching, fabrication techniques for large-scale and low-cost manufacturing, as well as device designs for dynamic displaying are discussed subsequently. In the end, the review surveys diverse applications of structural colors in various areas such as printing, sensing, and advanced photovoltaics.
Self-optimization examination system based on improved particle swarm optimization
Authors: Du Xiangran , Zhang Min , He Yulin 
Published: February 2023

Abstract
Artificial intelligence has been applied to many fields successfully and saved many human and material resources. The intelligent examination system is a typical application case, which makes teachers can not only master the study situation of every candidate at any time but also design further study plans with the help of the examination system. A self-optimization examination system is shown in this paper, which is carried out by an improved particle swarm optimization. The intelligent examination system can surmount two difficulties shown in the construction of the traditional examining system, one is the setting of the attributes of the examination questions, and another is the maintenance of the database of the examination questions. The experiment shows that the novel method can not only optimize the attributes of the questions in the examination database intelligently but also maintain the examination database effectively through massive training.
Formulation of a herbal topical cream against Tinea capitis using flavonoids glycosides from Dicerocaryum senecioides and Diospyros mespiliformis
Authors: Zhou Rudo , Dzomba Pamhidzai , Gwatidzo Luke 
Published: February 2023

Abstract
Topical fungal infections including, Tinea capitis with escalating resistance to conventional therapies are a rising concern globally. Studies have shown substantial in vitro efficacy of plant compounds against fungal pathogens. This study utilized flavonoid glycosides from Dicerocaryum senecioides and Diospyros mespiliformis as active compounds to formulate a topical cream against Tinea capitis. The in vitro test utilized disc diffusion assay prepared from fungal isolates obtained from individuals showing resistance to topical miconazole. Clinical trials were performed using volunteers. Both isolated strains exhibited substantial in vitro susceptibility to the cream formulation with inhibition zones ranging between 10 and 18 mm. MIC values for both test organisms ranged between 85 mg/ml and 120 mg/ml. The cream showed stability both physico-chemically and against microbial contamination. Physicochemical parameters evaluated include colour, pH, appearance, particle size, phase separation, phase inversion, creaming, spread-ability, electrical conductivity and in vitro occlusivity test and were within the accepted range. In limited clinical trials using volunteers, Tinea capitis started disappearing as from day 5 by topically applying the cream twice per day. All the patients were completely healed by the 7th day. The results of the study showed that flavonoid glycosides from D. senecioides and D. mespiliformis are good candidates to be utilized as active natural compounds against Tinea capitis resistant strains. Therefore more clinical trials and structural elucidations are recommended.
Increase of Claudin-5, ICAM-1 and eNOS expressions in human brain endothelial cells by ammonium chloride
Authors: Jufri Nurul Farhana , Salyam Tharshini , Ibrahim Farah Wahida , Yoganathan Dharrshine , Hamid Asmah , Abdul Latif Mazlyzam , Mohd Saleh Siti Nurdiyana , Juhari Nor Atikah Safirah 
Published: February 2023

Abstract

Objectives
Lysosomal dysfunction could lead to a failure in the degradation process of waste materials, especially for the elimination of aggregated, misfolded and senescence proteins or organelles. Human brain endothelial cells (HBECs) are a part of the blood-brain barrier and any disruption of lysosomal functions could affect the cellular functions of the HBECs. Protein expression studies on the cells could give an insight to associate lysosomal dysfunction on HBECs homeostasis. The aim of this study was to measure the cellular changes via the expression of several proteins such as Claudin-5, which is a tight junction protein; intracellular adhesion molecule 1 (ICAM-1), an inflammatory marker and endothelial nitric oxide synthase (eNOS), which provides nitric oxide (NO) for vasodilation. These components are important in maintaining homeostasis as the imbalance could lead to endothelial impairment linked brain related disorders such as neurodegenerative disease.

Methods
HBECs were treated with 10 mM ammonium chloride, which is a lysosome inhibitor for 1 h. The protein lysates were collected and subjected for ICAM-1 and Claudin-5 measurement by capillary immunoassay instrument, while eNOS by ELISA.

Results
Claudin-5 and ICAM-1 expression significantly increased (p<0.05). The ELISA results showed eNOS increment (p<0.001) compared to control. Lysosome inhibitor could be associated with accumulation of organelles that can stimulates inflammation and initial cellular responses.

Conclusions
Inhibition of lysosome by the inhibitor increases protein expressions related with endothelial function.
The effect of different anti-inflammatory treatment strategies on process of atherosclerosis in ankylosing spondylitis patients
Authors: Bozdayi Mehmet Akif , Ulusal Hasan , Turan Neytullah , Altindag Ozlem , Orkmez Mustafa , Taysi Seyithan , Tarakcioglu Mehmet 
Published: February 2023

Abstract

Objectives
Our aim in this study was to examine the effects of different anti-inflammatory treatment strategies on the process of atherosclerosis, which is an important cause of mortality in ankylosing spondylitis (AS) patients, by examining the possible effect of treatments on inflammation, lipid profile and oxidative stress parameters in patients with AS.

Methods
In this study, 32 healthy volunteers served as the control group in addition to a total of 76 AS patients who were divided into two groups according to whether they were receiving anti-TNF medications or not. We assessed the levels of inflammation, oxidative stress, lipid profile parameters, and oxidized low-density lipoprotein (oxLDL). The atherogenic index of plasma (AIP), non-HDL cholesterol levels, BASDAI, and BASFI scores were also calculated.

Results
AS patient groups and the control group had similar lipid profile parameters, thiol-disulfide homeostasis metrics, non-HDL cholesterol, oxLDL, and AIP levels (p>0.05). In contrast to AS patients receiving non-anti-TNF treatment, the BASDAI and BASFI scores, ESR, and CRP levels were lower in AS patients receiving anti-TNF treatment (p<0.05). In contrast to the controls, AS patients demonstrated high TOS and OSI values (p<0.05).

Conclusions
AS patients face increased oxidative stress that does not correlate with inflammatory status and disease activation level. Anti-TNF alpha treatment may reduce some risk factors of atherosclerotic CVD in AS patients.
Ischemia – modified albumin by albumin cobalt binding test: a false myth or reality
Authors: Yücel Doğan 
Published: February 2023

Abstract
Scientific knowledge should be based on evidence. However, some scientific studies can be carried out without sufficient evidence. And these studies may mislead subsequent studies. Ischemia-modified albumin (IMA) is a relatively newly proposed biomarker. It is used not only for myocardial ischemia but also used for other pathological conditions in the body. IMA is commonly measured by albumin cobalt binding (ACB) assay. ACB is a simple colorimetric assay performed in patients’ sera. It is claimed that because of the ischemia or ischemia-reperfusion, the molecular structure of the N-terminus of human serum albumin is changed and therefore it cannot bind metal ions and cobalt ions added into the reaction mixture react with dithiothreitol to give a brown color. The clinical performance of the ACB assay is poor and it has not a strong correlation with other ischemia biomarkers. There are many analytical uncertainties in ACB assay and IMA as well. Despite the uncertainties, the ACB assay is still commonly used for many research studies. Therefore the theory of the ACB assay should be questioned. In this opinion paper, we discussed these uncertainties. In conclusion, there is insufficient evidence for the existence of IMA as a biomarker. The ACB assay essentially measures serum albumin concentration. There are many other interfering factors with the ACB assay. Therefore, the measurement of IMA in any pathological condition is a useless effort.
Crotofoligandrin, a new endoperoxide crotofolane-type diterpenoid from the twigs of Croton oligandrus Pierre ex. Hutch (Euphorbiaceae)
Authors: Tatsinda Tsapi Vanneck Bedel , Fotsing Fongang Yannick Stéphane , Awantu Angelbert Fusi , Kezetas Bankeu Jean Jules , Lateef Mehreen , Chouna Jean Rodolphe , Nkeng-Efouet-Alango Pépin , Ali Muhammad Shaiq , Lenta Bruno Ndjakou 
Published: February 2023

Abstract
Crotofoligandrin (1), a new endoperoxide crotofolane-type diterpenoid was isolated from the dichloromethane/methanol (1:1) extract of the twigs of Croton oligandrus Pierre Ex Hutch along with thirteen known secondary metabolites including 1-nonacosanol (2), lupenone (3), friedelin (4), β-sitosterol (5), taraxerol (6), (−)-hardwickiic acid (7), apigenin (8), acetyl aleuritolic acid (9), betulinic acid (10), fokihodgin C 3-acetate (11), D-mannitol (12), scopoletin (13) and quercetin (14). The structures of the isolated compounds were determined based on their spectroscopic data. The crude extract and the isolated compounds were assessed in vitro for their antioxidant, lipoxygenase, butyrylcholinesterase (BChE), urease and glucosidase inhibitory potentials. Compounds 1–3, and 10 displayed activities on all the performed bioassays. All the tested samples showed strong to significant antioxidant activity with compound 1 being the most potent (IC50 39.4 μM).
Prediction of chromatin looping using deep hybrid learning (DHL)
Authors: Chiliński Mateusz , Halder Anup Kumar , Plewczynski Dariusz 
Published: February 2023

BackgroundWith the development of rapid and cheap sequencing techniques, the cost of whole‐genome sequencing (WGS) has dropped significantly. However, the complexity of the human genome is not limited to the pure sequence—and additional experiments are required to learn the human genome’s influence on complex traits. One of the most exciting aspects for scientists nowadays is the spatial organisation of the genome, which can be discovered using spatial experiments ( e.g., Hi‐C, ChIA‐PET). The information about the spatial contacts helps in the analysis and brings new insights into our understanding of the disease developments.MethodsWe have used an ensemble of deep learning with classical machine learning algorithms. The deep learning network we used was DNABERT, which utilises the BERT language model (based on transformers) for the genomic function. The classical machine learning models included support vector machines (SVMs), random forests (RFs), and K‐nearest neighbor (KNN). The whole approach was wrapped together as deep hybrid learning (DHL).ResultsWe found that the DNABERT can be used to predict the ChIA‐PET experiments with high precision. Additionally, the DHL approach has increased the metrics on CTCF and RNAPII sets.ConclusionsDHL approach should be taken into consideration for the models utilising the power of deep learning. While straightforward in the concept, it can improve the results significantly.
An adaptive fuzzy semi-parametric regression model using TPB and ABC-BPNN
Authors: Jiang Keli , Lu Qiujun 
Published: February 2023

Abstract
In this paper, a new hybrid method is developed that incorporates the rationale of truncated power basis (TPB) and artificial bee colony-back propagation neural networks (ABC-BPNN) into an adaptive fuzzy semi-parametric regression model yielding more accurate results and better generalization ability. The proposed adaptive fuzzy semi-parametric regression model comprises sub-model formulation and approximates the observed fuzzy outputs from the outside employing neural networks computation, such that the proposed adaptive fuzzy regression model better explains the inherent dependence and vagueness that exist in a given dataset. Using the cross-validation criterion and absolute deviation-based distance measures for LR-type fuzzy numbers, a target function optimization problem of constructing the adaptive fuzzy semi-parametric regression is performed by solving the smooth function, bandwidth of kernel function and regression coefficients. This strategy significantly increases the goodness of fit for the proposed algorithm and offers a dependence framework among magnitude and uncertainty for the fuzzy regression model. We also use three formula measures to evaluate the fit quality of the regression results within each membership function as well as in the center or spread tendency property, respectively. The proposed algorithm is numerically evaluated on three experimental examples including a simulation study and two practical cases to prove its practicality and efficiency. Comparative analyses of our proposed method are provided in order to support its cogency, and the results show that our proposed model is more effective and stable than some other existing fuzzy regressions.
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes
Authors: Onfelt Bjorn , Sandoz Patrick , Kuhnigk Kyra , Szabo Edina , Thunberg Sarah , Erikson Elina , Sandström Niklas , Verron Quentin , Brech Andreas , Watzl Carsten , Wagner Arnika , Alici Evren , Malmberg Karl-Johan , Uhlin Michael 
Published: February 2023

Abstract
Vγ9Vδ2 is the largest γδ T cell subset in human peripheral blood. These cells get activated and proliferate in response to phosphoantigens produced by infected or tumour transformed cells. Although Vγ9Vδ2 T cells have shown evidence of innate-like cytotoxicity, their modus operandi remains poorly understood. In this work, we have used single-cell imaging in microwells to track the dynamics and cytotoxic functions of Vγ9Vδ2 T cells upon interactions with tumour target cells under different stimuli and phases of expansion. While Vγ9Vδ2 T cell killing was dominated by degranulation, the availability of lytic molecules appeared tightly regulated in time and space. In particular, granzyme B was abundant but its limited co-occurrence with perforin restrained serial killing of tumour cells. Altogether, our data provide new insights into the Vγ9Vδ2 T cell cytotoxic arsenal and functions, which can guide the development of more efficient γδ T cell based adoptive immunotherapies.
Facile synthesis of NaA zeolite supported Co2Fe1 for highly efficient degradation of Acid Orange 7 by activation of peroxymonosulfate
Authors: Xu Yue , Liu Jian , Zhao Yi , Yi Zhengji 
Published: February 2023

Abstract
The development of heterogeneous Co-based catalysts with an effective combination mode of Co/Fe and supporter, a facile synthetic method, and a low treatment costs is an important environment challenge for azo dyes degradation by peroxymonosulfate (PMS) activation. In this study, NaA zeolite supported CoxFey with various molar ratio of Fe/Si and Co/Fe was synthesized by a facile hydrothermal process, and used to activate PMS for Acid Orange 7 (AO7) degradation. NaA zeolite supported Co2Fe1 with the Fe/Si molar ratio of 1:10 showed superior catalytic performance compared with other NaA zeolite supported CoxFey. In a system containing 0.6 g/L catalysts, 4 mM PMS, pH 5 and T = 30℃, 95.8% AO7 and 79.1% COD conversion could be achieved at 20 and 60 min, respectively, and the first order kinetic rate constant reached 0.14795 min− 1. Moreover, NaA zeolite supported Co2Fe1/PMS system exhibited excellent catalytic effect in a wide pH range of 3–9. Temperature had an obvious effect on AO7 degradation, and the activation energy was 31.36 kJ/mol. HCO3− demonstrated an obvious depression on AO7 degradation, while Cl−, SO42− and H2PO4− had a relatively poor impact. Quenching experiments showed that both sulfate radicals (SO4•-) and hydroxyl radicals (·OH) were generated in the PMS reaction system, and the (SO4•-) was the dominant active radical. During 3 cycles experiments, an acceptable AO7 conversion ratio (91.8%) within 30 min was arrived, suggesting the good stability of NaA zeolite supported Co2Fe1.