bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of expressive writing on Chinese cancer patients: A systematic review and meta‐analysis of randomized control trails
Authors: Zhang Chen , Xu Shuo , Wen Xinyue , Liu Mowen 
Published: June 2023

AbstractCancer patients in China encounter distinctive challenges stemming from cultural disparities and variations in the healthcare systems. This meta‐analysis aimed to provide a synthesis of the expressive writing (EW) interventions delivered to Chinese cancer patients and assess the pooled effect of EW on their well‐being. The review adheres to the latest PRISMA 2020 guidelines to ensure transparency and rigour. Randomized control trials (RCTs) published before 1 April 2023, and meeting the inclusion criteria were included. Keywords searching was performed in both English and Chinese electronic databases. Ten RCTs were identified and included in the analysis. The results showed that EW usually encompassed four to six writing sessions; the most common writing themes were ‘emotional expression’, ‘cognitive appraisal’, ‘benefit finding’, ‘coping strategies’ and ‘looking to the future’. The meta‐analysis suggested that EW had a substantial impact on reducing anxiety levels (Hedges' g = −1.22, 95% CI [−1.54, −0.90], I2 = 0.00%). It is worth noting that although the results of these studies could not be statistically synthesized, their individual findings suggest that EW may be beneficial in reducing anxiety, self‐perceived burden and depressive symptoms, as well as increasing self‐efficacy in Chinese cancer patients. In conclusion, this review highlights the importance and effectiveness of Ewin alleviating anxiety among Chinese cancer patients and underscores the potential benefits of incorporating EW into comprehensive care programmes for cancer patients in China. More RCTs are needed to explore the broader impact of EW in China.
Effects of Omega‐3 as an adjuvant in the treatment of periodontal disease: A systematic review and meta‐analysis
Authors: Miroult Clementine , Lasserre Jerome , Toma Selena 
Published: June 2023

AbstractBackground and ObjectivesPromoting resolution of inflammation using new classes of lipids mediators has been proposed for the management of inflammatory disease. This systematic review and meta‐analysis aimed to evaluate the benefits of the use of omega‐3 fatty acids as an adjuvant in the nonsurgical treatment of periodontitis.Material and MethodsThe data search was conducted into three main databases: PubMed, Embase, and Cochrane. The search equation was built around the PICO framework in which the population was constituted by human adults suffering from chronic periodontitis that had to be treated with conventional SRP with the adjunction of omega‐3 fatty acids (I) or without the adjunction of omega‐3 fatty acids (C), with, as a first outcome the probing pocket depth reduction (PPD) and as a second outcome the clinical attachment loss reduction (CAL). Risk of bias within studies was evaluated for each included study using the Cochrane collaboration tool for randomized studies (RoB Tool). A meta‐analysis was performed using REVMAN 5.3.ResultsAfter a global search, 117 studies were selected but only seven of them were eligible for the systematic review and meta‐analysis. Six out of seven studies showed a significantly better PPD reduction in the omega‐3 fatty acids group compared to the control group and five out of seven studies showed a significantly better CAL reduction in the omega‐3 fatty acids group compared to the control group. The meta‐analysis showed a statistically significant difference for PPD reduction (SMD: −0.78 [95% CI: −1.02, −0.54, p < .0001]) and CAL reduction (SMD: −0.80 [95% CI: −1.04, −0.56, p < .0001]) in favor of the test group.ConclusionAfter scaling and root planning, PPD reduction and CAL reduction were observed in both control and test groups, but with statistically significant better values for the omega‐3 fatty acids group. Patients suffering from periodontitis could benefit from the use of omega‐3 fatty acids to increase the effectiveness of a nonsurgical treatment.
Refine control methodology and implementation of capacitor voltage control for improved switched inductor Z‐source inverter
Authors: Ismeil Mohammed , Orabi Mohammed , Ahmed Emad , Hussein Hany S. 
Published: June 2023

SummaryNowadays, Z‐source inverter (ZSI) has received several attentions compared to other power converters owing to their simplicity and reliability. In this paper, a refine control methodology of capacitor voltage control is presented based on third‐order small signal analysis. The proposed control is applied to the improved switched inductor ZSI (ISL‐ZSI). Proportional, integral, and derivative controller (PID) is adopted due to their capability to operate with large operation levels, reliable operation, and cheaper implementation. In addition, the function of this control can be achieved even with incomplete system data or parameters variations. ISL‐ZSI has been presented because of its advantages such as the high gain of direct current voltage, low voltage stress for both the Z‐network and the inverter bridge switches, and ensuring good soft starting. In addition, the inrush current has been removed based on its configuration. The proposed control is validated by both experimental and simulation results under input voltage change, load change, and steady‐state operations using DSP F28335 and MATLAB SIMULINK Real‐Time Workspace.
Utility of cytopathologic diagnosis of adult solid renal lesions: An academic Institution's 10‐year experience
Authors: Satturwar Swati , Quiroga‐Garza Gabriela M. , Xing Juan , Khader Samer N. 
Published: June 2023

AbstractBackgroundFine needle aspiration (FNA) and/or needle core biopsy (NCB) are increasingly used for managing patients with renal lesions, especially small renal masses (SRMs). One of the treatment options for SMRs is active surveillance. Hence, accurate diagnosis of renal lesions is critical for treatment planning. The aim of this study is to investigate the utility of FNA and/or NCB in the diagnosis of adult renal lesions at our institute.Materials and MethodsLaboratory information system was queried over a period of 10 years (2011–2020) to identify cases of FNA and/or NCB with touch preparation (TP) of adult renal masses. Patient demographics, cytopathologic diagnoses, ancillary tests and follow‐up surgical resection data were reviewed and correlated.ResultsA total 138 cases from 138 patients (male = 80, female = 58) were identified. Sixty‐one (44.20%) cases had FNA and NCB, 48 (34.78%) had NCB only and 29 (21.01%) had FNA only. 118 (85.50%) cases had definitive diagnoses and 13 (9.42%) had indeterminant diagnoses and seven cases were non‐diagnostic (5.07%). Most common benign and malignant diagnoses were oncocytoma and clear cell renal cell carcinoma (CCRCC). 41/138 (29.71%) cases had follow‐up resection. There were no false positive or false negative cases. Subtyping was feasible in majority cases with only 3/138 (2.17%) misclassified cases.ConclusionsMajority of renal masses (85.50%) had definitive cytology diagnoses. Only three had misclassification. FNA and/or NCB are useful methods in diagnosing and subclassifying adult renal masses and showed high accuracy (91.89%) when compared to surgical resections.
Design and synthesis of guaianolide‐germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma
Authors: Yan Jia‐Xin , Li Qi‐Hao , Li Tian‐Ze , Huang Zhi‐Yan , Ma Yun‐Bao , Chen Ji‐Jun 
Published: June 2023

AbstractInspired by our previous finding that disesquiterpenoids showed more potent antihepatoma cytotoxicity than their corresponding parent monomers, natural product‐like guaianolide‐germacranolide heterodimers were designed and synthesized from guaianolide diene and germacranolides via a biomimetic Diels–Alder reaction to provide three antihepatoma active dimers with novel scaffolds. To explore the structure–activity relationship, 31 derivatives containing ester, carbamate, ether, urea, amide, and triazole functional groups at C‐14′ were synthesized and evaluated for their cytotoxic activities against HepG2, Huh7, and SK‐Hep‐1 cell lines. Among them, 25 compounds were more potent than sorafenib against HepG2 cells, 15 compounds were stronger than sorafenib against Huh7 cells, and 17 compounds were stronger than sorafenib against SK‐Hep‐1 cells. Compound 23 showed the most potent cytotoxicity against three hepatoma cell lines with IC50 values of 4.4 µM (HepG2), 3.7 µM (Huh7), and 3.1 µM (SK‐Hep‐1), which were 2.7‐, 2.2‐, and 2.8‐fold more potent than sorafenib, respectively. The underlying mechanism study demonstrated that compound 23 could induce cell apoptosis, prevent cell migration and invasion, cause G2/M phase arrest in SK‐Hep‐1 cells. Network pharmacology analyses predicted PDGFRA was one of the potential targets of compound 23, and surface plasmon resonance (SPR) assay verified that 23 had strong affinity with PDGFRA with a dissociatin constant (KD) value of 90.2 nM. These promising findings revealed that structurally novel guaianolide‐germacranolide heterodimers might provide a new inspiration for the discovery of antihepatoma agents.
Planting design influences green infrastructure performance: Plant species identity and complementarity in rain gardens
Authors: Bruner Sarah G. , Palmer Matthew I. , Griffin Kevin L. , Naeem Shahid 
Published: June 2023

AbstractGreen infrastructure's capacity to mitigate urban environmental problems, like heat island effects and excessive stormwater runoff, is partially governed by its plant community. Traditionally, green infrastructure design has focused on engineered aspects, such as substrate and drainage, rather than on the properties of its living components. Since the functioning of these plant assemblages is controlled by ecophysiological processes that differ by species, the identity and relative abundance of the species used will influence green infrastructure performance. We used trait‐based modeling to derive principles for the effective composition of green infrastructure plant assemblages, parameterizing our model using the vegetation and ecophysiological traits of the species within New York City rain gardens. Focusing on two plant traits that influence rain garden performance, leaf surface temperature and stomatal conductance, we simulated the cumulative temperature and transpiration for plant communities of differing species composition and diversity. The outcomes of the model demonstrate that plant species composition, species identity, selection effects, and interspecific complementarity increase green infrastructure performance in much the way biodiversity affects ecosystem functioning in natural systems. More diverse assemblages resulted in more consistent transpiration and surface temperatures, with the former showing a positive, saturating curve as diversity increased. While the dominant factors governing individual species leaf temperature were abiotic, transpiration was more influential at the community level, suggesting that plants within diverse communities may be cooler in aggregate than any individual species on its own. This implies green infrastructure should employ a variety of vegetation; particularly plants with different statures and physical attributes, such as low‐growing ground covers, erect herbaceous perennials, and shrubs.
Delayed recovery and host specialization may spell disaster for coral‐fish mutualism
Authors: Froehlich Catheline Y. M. , Klanten O. Selma , Hing Martin L. , Dowton Mark , Wong Marian Y. L. 
Published: June 2023

AbstractMutualisms are prevalent in many ecosystems, yet little is known about how symbioses are affected by ecological pressures. Here, we show delayed recovery for 13 coral‐dwelling goby fishes (genus Gobiodon) compared with their host Acropora corals following four consecutive cyclones and heatwaves. While corals became twice as abundant in 3 years postdisturbances, gobies were only half as abundant relative to predisturbances and half of the goby species disappeared. Although gobies primarily occupied one coral species in greater abundance predisturbances, surviving goby species shifted hosts to newly abundant coral species when their previously occupied hosts became rare postdisturbances. As host specialization is key for goby fitness, shifting hosts may have negative fitness consequences for gobies and corals alike and affect their survival in response to environmental changes. Our study is an early sign that mutualistic partners may not recover similarly from multiple disturbances, and that goby host plasticity, while potentially detrimental, may be the only possibility for early recovery.
The role of body mass in limiting post heat‐coma recovery ability in terrestrial ectotherms
Authors: Leong Chi Man , Hui Tin Yan , Guénard Benoit 
Published: June 2023

AbstractUnder global warming, animal species show shrinking body size responses, cascading deep changes in community structure and ecosystem functions. Although the exact physiological mechanisms behind this phenomenon remain unsolved, smaller individuals may benefit from warming climate more than larger ones. Heat‐coma, a physiological state with severe consequences on locomotion ability, is often considered as an “ecological death” scenario under which individuals are unable to escape and exposed to predation, further heat injury, and other hazards. Species are expected to increasingly encounter heat‐coma temperature thresholds under warming climate, and body size may be an important trait for thermoregulation in particular for ectotherms. The relationship between heat‐coma and shrinking body size remains, however, unclear. Yet, recovery after short‐term heat‐coma is possible, but little is known about its importance in thermal adaptation and how organismal size correlates with post heat‐coma recovery. Here, using ants as a model system, we firstly examined the fate of heat‐comatose individuals under field conditions to quantify the ecological benefits of post heat‐coma recovery. Then, we quantified ants' recovery ability after heat‐coma using a dynamic thermal assay in the laboratory and asked if thermal resilience varies between species with different body mass. Our results confirm that heat‐coma represents an inherent ecological death where individuals failed to recover from coma suffer strong predation pressure. Additionally, following phylogenetic signals inclusion, organisms with small mass were more likely to recover, supporting the temperature‐size rule in thermal adaptation and recent studies showing a decrease in body size composition of ectotherm community under warmer climatic conditions. Body size as a fundamental trait in ecology thus affects ectotherm survival under thermal stress, which may drive species body size adaptations and community composition under future warming scenarios.
Does life form affect tree species assembly? A demographic study across the life history of a temperate forest in Japan
Authors: Wijenayake Pavithra Rangani , Masaki Takashi , Shibata Mitsue , Kubota Yasuhiro 
Published: June 2023

AbstractIn this study, the dominant mechanism that defines the species assembly in an old‐growth temperate forest was investigated by analyzing the species specificity of demographic parameters in relation to the life history stage, testing the hypotheses that early life stages should be more critical for sub‐canopy species than canopy species. Data for 17 major tree species in the Ogawa Forest Reserve (OFR) in Japan were analyzed, together with data from early stages (seed production, seed dispersal, and seedling emergence) to dbh‐based transition probability and survival stages (5–80 cm). Both datasets were subjected to principal components analysis (PCA): one included tree of dbh < 35 cm for all species (small‐sized trees of all species [SSAS]) and the other included tree species with dbh ≥ 55 cm (large‐sized species [LSS]). The most influential was the growth–survival trade‐off for trees at small‐to‐middle‐sized stages (dbh: 10–40 cm), which captured a moderate proportion of the demographic variation (24.3%–26.4%). At these stages, some Quercus species were characterized by higher growth, and some Fagus and Acer species by shade tolerance. Behavior during early‐to‐late life stages was the second most important dimension, for SSAS, sub‐canopy tree species showed high survival at early life stages than canopy species as the second important dimension, which differed between the SSAS‐ and LSS‐based PCAs. The relationship between functional traits and PCA axis dimensions varied with PCA type and dimension. The growth–survival trade‐off in the OFR was closely associated with maximum tree height, a proxy for life form, and specific leaf area a proxy for shade tolerance. This finding implies a significant role for the growth–survival trade‐off in stable species coexistence by maintaining mutual claims to vertical light resources and allowing the more efficient use of the forest canopy space. However, there was no significant association between wood density and demographic variables. Our study shows that interspecies relationships vary with the life history stage and that early life stages are more critical for sub‐canopy species than canopy species in temperate forests, where the entire life history of the trees must be considered focusing on the difference in life forms.
Long‐term analysis of body condition reveals species coupling and the impacts of an invasion
Authors: Martin Benjamin E. , Vander Zanden M. Jake 
Published: June 2023

AbstractPredator–prey coupling can result in oscillations of predator–prey densities. These oscillations in predator–prey densities correspond to oscillations in intraspecific competition where a high population density causes high intraspecific competition. Strong coupling of native species can however be disrupted by the introduction of invasive species into food webs. Here, we investigated how the body condition (body mass relative to body length) of a predator, lake trout, and its primary prey, cisco, changed as their respective population densities shifted. We found that the body condition of lake trout and cisco was strongly influenced by their respective population densities, that is, density dependence. The body conditions of lake trout and cisco were also inversely related, which highlights strong predator–prey coupling. Further, we were able to detect the impacts of a recent invasive species, Bythotrephes, as we saw size‐specific shifts in the body condition of prey following the invasion. Overall, this study highlights how the long‐term study of a simple measure, body condition, can reveal predator–prey coupling and yield new insights into the impacts of an invasive species.
Probabilistic analysis of seismic mitigation of base‐isolated structure with sliding hydromagnetic bearings based on finite element simulations
Authors: Peng Yongbo , Ding Luchuan , Liu Jiangtao , Chen Jianbing 
Published: June 2023

AbstractBase isolation is one of the most efficient methods for seismic mitigation of building and bridge structures in high‐intensity areas. However, the base‐isolated structure designed according to current codes based on the local seismic hazard and a few station records might not guarantee the performance of the base isolation system and ensure the safety of the structure. Carrying out a probabilistic analysis of seismic mitigation of base‐isolated structures, considering the randomness associated with earthquake ground motions, is thus necessary. To this end, the stochastic seismic response and reliability analysis of base‐isolated structures subjected to stochastic ground motions are conducted in this study, in conjunction with the probability density evolution method and the principle of equivalent extreme value event. The recently developed sliding hydromagnetic bearing is employed to constitute the base isolation layer of the base‐isolated structure. A refined finite element analysis is carried out to accurately reveal the dynamic characteristics of the base‐isolated structure. It is shown that the base‐isolated structure can be well simulated by the finite element model, which is verified through a comparative study with the results of shaking‐table tests. The base‐isolated structure gains a sound seismic mitigation compared to the base‐fixed structure in a probabilistic sense, and can ensure the safety of the structure by deploying a moderately designed base isolation system.
Prognostic significance of plasma chloride in elderly patients hospitalized for acute heart failure
Authors: Llàcer Pau , Croset François , Núñez Julio , Campos Jorge , Fernández Cristina , Fabregate Martín , Del Hoyo Beatriz , Ruiz Raúl , López Genoveva , Tello Susana , Lorenzo Ana , Fernández José María , Manzano Luis 
Published: June 2023

AbstractAimsPrevious studies demonstrated the relationship between hypochloraemia and poor prognosis in patients hospitalized for acute heart failure (AHF). However, the usefulness of chloride in clinical practice remains uncertain, notably in very old patients with predominantly heart failure (HF) with preserved ejection fraction (HFpEF). We aimed to evaluate the prognostic impact of chloride in a cohort of very aged patients with AHF and the possible existence of different phenotypes of hypochloraemia with distinct clinical significance.Methods and resultsIt was an observational study of 429 patients hospitalized for AHF in which chloraemia was measured. Two different phenotypes of hypochloraemia were identified by their relationship with estimated plasma volume status (ePVS) as a proxy of intravascular congestion. The endpoint of interest was time to all‐cause mortality and the composite of death and/or HF readmission. A multivariable Cox proportional hazard regression model was constructed to analyse the endpoints. The median age was 85 (78–92) years, 266 (62%) were women, and 80% had HFpEF. After multivariable analysis, chloraemia, but not natraemia, was associated with the risk of death and HF readmission in a U‐shaped pattern. The phenotype characterized by hypochloraemia and low ePVS (depletional) was associated with an increased risk of mortality when compared with patients with normochloraemia [hazard ratio (HR) 1.86, P = 0.008]. In contrast, hypochloraemia with high ePVS (dilutional) had no prognostic significance (HR 0.94, P = 0.855).ConclusionsIn very old patients hospitalized with AHF, plasma chloride was associated with the risk of death and HF readmission in a U‐shaped pattern and could potentially be used for congestion phenotyping.
An Unexpected New Member of the Family of Lithium Oxonitridosilicates – Li7Si2NO6
Authors: Rießbeck Kilian M. , Seibald Markus , Schwarzmüller Stefan , Baumann Dominik , Huppertz Hubert 
Published: June 2023

AbstractWith Li7Si2NO6, a new member of the family of lithium oxonitridosilicates with a so far unseen structure type could be synthesized. Using a high‐temperature solid‐state reaction in open nickel crucibles under nitrogen flow, it was possible to obtain single crystals from the starting materials SiO2, Li3N, and Li2O at temperatures of 900 °C. Single crystal X‐ray diffraction data yielded lattice parameters of a=5.0934(2), b=7.4128(2), c=8.5918(2) Å, α=75.16(1)°, β=87.36(1)°, γ=73.01(1)° and a cell volume of V=299.75(2) Å3. The compound, crystallizing in the triclinic space group P
(no. 2), consists of a highly condensed anionic network built up by [SiNO3]‐, [LiO4]‐, and [LiN2O2]‐tetrahedra as well as lithium in octahedral coordination as completing cation. With an activation barrier of 695 meV for lithium migration, Li7Si2NO6 is a potential lithium‐ion conductor. The structure allows a classification not only as a sorosilicate but also as a tecto‐lithosilicate and most precisely as a lithium oxonitridolithosilicate, when the different coordinations of the lithium ions are taken into account. Interestingly, the new compound is none of the several proposed representatives of the lithium oxonitridosilicates, thus expanding this substance class unexpectedly.