bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ressentiment and power: On Reginster's The Will to Nothingness
Authors: Jay Wallace R. 
Published: June 2023

AbstractA critical discussion of Bernard Reginster's book The Will to Nothingness. The contribution engages with Reginster's interpretation of Nietzschean ressentiment, arguing that it is an essentially interpersonal attitude in two different senses. It is a response to a social situation of structural deprivation, and it involves an element of antagonism toward those who are better off within this social structure. The contribution then discusses Reginster's claim that modern morality restores the sense of power of the masses by adjusting the goals that they aim to pursue. I argue that this interesting interpretation does not do full justice to the themes of hostility or hatred that permeate the Genealogy of Morals, extending from Nietzsche's discussion of the slave revolt to his treatments of the bad conscience and of ascetic ideals.
Replies to Wallace, Queloz, and Kirwin
Authors: Reginster Bernard 
Published: June 2023

AbstractIn this article, I reply to the comments offered by R. Jay Wallace, Matthieu Queloz, and Claire Kirwin on my book, The Will to Nothingness. An Essay on Nietzsche's Genealogy of Morality (OUP, 2021). These comments and my replies cover central features of the book, including my analysis of ressentiment as an expression of the will to power; the concept of self‐undermining functionality I introduce to make sense of Nietzsche's critique of the ascetic ideal; and my reasons for omitting to examine the “unconditional will to truth,” which he presents as the latest embodiment of this ideal.
Treatment of hemiplegic migraine with anti‐calcitonin gene‐related peptide monoclonal antibodies: A case series in a tertiary‐care headache center
Authors: Danno Daisuke , Ishizaki Kumiko , Kikui Shoji , Takeshima Takao 
Published: June 2023

AbstractHemiplegic migraine (HM) is a subtype of migraine with aura that includes motor weakness; such headaches can be excruciating. The presence of not only headache but also aura symptoms of HM increase the burden on patients, and the treatment of HM is sometimes challenging. Monoclonal antibodies (mAbs) targeting the calcitonin gene‐related peptide (CGRP) pathway are novel migraine preventive treatments that have shown promising efficacy in patients with migraine; however, there have been no reports regarding their efficacy in HM to date. Six patients with HM were treated with galcanezumab in a tertiary‐care headache center. After 3 months of treatment, the number of monthly days with headache of at least moderate severity was reduced in three patients. The number of days each month with weakness was also reduced in four patients. Furthermore, the Patient's Global Impression of Change and change in Migraine Disability Assessment total score, were improved in five of the six patients after the treatment; however, the change from baseline in days with bothersome symptoms did not show any specific trends in our patients. Notably, no adverse events were reported during the treatments. The mechanism underlying the improvement in aura symptoms in our patients is not clear; however, we speculate that a small amount of CGRP mAbs have a direct mode of action in the central nervous system; alternatively, blocking the CGRP pathway in the periphery may secondarily inhibit cortical spreading depression. While prudence must be practiced, galcanezumab was still generally effective in HM and well tolerated. Further prospective clinical studies will more clearly elucidate the effects of CGRP mAbs in patients with HM.
Utilising the potential of job postings for auditing learning outcomes and improving graduates' chances on the labour market
Authors: Piróg Danuta , Hibszer Adam 
Published: June 2023

AbstractThe objective of the paper was to outline the possibility of utilising information from online job postings and text‐mining analyses to identify mismatches and gaps between learning outcomes prepared by universities, and the knowledge and skills that employers need. The study uses job advertisement contents and learning outcomes documents from universities. We analysed both data sets using word importance classification, cluster analysis and hierarchical clustering. Word importance classification presented the mismatches in a quantitative and diagram format. Cluster analysis and hierarchical clustering provided information on how to correct the detected gaps and mismatches. The study empirically corroborates that the method we put forward for analysing both sources (LOs and job ads) helps identify and assess the significance of gaps and mismatches in the approaches to knowledge and skills adopted by universities and employers. Consequently, the method can be helpful during the auditing process and while implementing market‐oriented curriculum changes.
Meaningful engagement through critical reflexivity: Engaging people with lived experience in continuing mental health professional development
Authors: Harris Holly , Clarkin Chantalle , Rovet Jordana , Crawford Allison , Johnson Andrew , Kirvan Anne , Gruszecki Sam , Wang Stephanie , Soklaridis Sophie 
Published: June 2023

AbstractEngaging people with lived experience of mental health system encounters in the design and actualization of continuing professional development initiatives for mental health professionals can have transformative systemic impacts. Yet, despite evidence that involving people with lived experience benefits mental health professional education, far less focus has been placed on how to engage people with lived experience in continuing professional development initiatives. Tensions persist regarding the role of lived experience perspectives in continuing professional development, as well as how to establish people with lived experience as partners, educators and leaders in a thoughtful way. We propose that meaningful and equitable partnerships with people with lived experience can be realized by engaging in critical reflexivity and by systematically challenging assumptions. This paper explores three topics: (1) the current state of engagement with people with lived experience in continuing professional development initiatives; (2) barriers to meaningful engagement and (3) recommendations for using critical reflexivity to support the involvement and leadership of people with lived experience in continuing professional development for mental health professionals.Patient or Public InvolvementThis viewpoint manuscript was co‐designed and co‐written by people with diverse lived and learned experiences. Each author's professional roles involve meaningfully and equitably partnering with and centring the perspectives of those with lived experience of mental health system encounters. In addition, approximately half of the authorship team identifies as having lived experience of accessing the psychiatric system and/or supporting family members who are navigating challenges related to mental health. These lived and learned experiences informed the conception and writing of this article.
Five dimensions of cleansing: A holistic view on the facets and importance of skin cleansing
Authors: Blaak Jürgen , Grabmann Svenja , Simon Isabel , Callaghan Theresa , Staib Peter 
Published: June 2023

AbstractCleansing is an important human ritual practised for hygiene, well‐being and relaxation over centuries. As part of body care it is often taken for granted, yet its relevance cannot be underestimated. Although cleansing the skin may seem trivial to some, it is accepted, that this fundamental function of skin cleansing products is highly complex, diverse and crucial for a variety of reasons in the personal, public, healthcare and dermatological settings. Employing a comprehensive and strategic approach in viewing cleansing and its rituals, supports innovation, understanding and development. Apart from being a fundamental function, as far as we know, there is no comprehensive presentation of skin cleansing with all its effects besides ‘removing dirt’. To our knowledge, comprehensive analyses on the multi‐dimensional facets of skin cleansing are either rare or not published. Against this background, we examine the importance of cleansing in terms of function, relevance and concepts. First, the key functions and efficacies of skin cleansing were investigated by literature research. Based on this survey, the functions were analysed, sorted and merged and a novel approach to skin cleansing ‘dimensions’ was developed. Herewith, we took into consideration the evolution of skin cleansing in terms of concept evolution, complexity and testing methods for cleansing products and their claims. Several multi‐dimensional functions of skin cleansing were identified and then established into five skin cleansing dimensions, namely: hygienic and medical importance; socio‐cultural and interpersonal relevance; mood, emotion and well‐being; cosmetic and aesthetic function; corneobiological interactions. It became obvious, that these five dimensions with their corresponding 11 sub‐dimensions, are influenced by each other throughout history by culture and society, technical progress, scientific knowledge and consumer trends. This article presents the enormous complexity of skin cleansing. Skin cleansing has evolved from basic care up to a highly complex and diverse cosmetic product category in terms of technology, efficacy and usage routine(s). In view of future challenges, such as the effects of climate and associated lifestyle changes, the development of skin cleansing will remain an exciting and important topic and thus will finally, again, further increase the complexity of skin cleansing itself.
The erectile and ejaculatory implications of the surgical management of rectal cancer
Authors: Ghomeshi Armin , Zizzo John , Reddy Raghuram , White Joshua , Swayze Aden , Swain Sanjaya , Ramasamy Ranjith 
Published: June 2023

AbstractColorectal cancer is a significant cause of cancer‐related deaths worldwide. Although advances in surgical technology and technique have decreased mortality rates, surviving patients often experience sexual dysfunction as a common complication. The development of the lower anterior resection has greatly decreased the use of the radical abdominoperineal resection surgery, but even the less radical surgery can result in sexual dysfunction, including erectile and ejaculatory dysfunction. Improving the knowledge of the underlying causes of sexual dysfunction in this context and developing effective strategies for preventing and treating these adverse effects are essential to improving the quality of life for postoperative rectal cancer patients. This article aims to provide a comprehensive evaluation of erectile and ejaculatory dysfunction in postoperative rectal cancer patients, including their pathophysiology and time course and strategies for prevention and treatment.
Clinical effect of stem cell transplantation combined with 308‐nm excimer laser therapy for 56 cases of vitiligo
Authors: Liu Jingwei , Chen Qingqing 
Published: June 2023

AbstractObjectiveTo probe the clinical effect of stem cell transplantation in combination with 308‐nm excimer laser therapy for vitiligo and to analyze its value in clinical application.MethodsA total of 56 patients with stable non‐segmental vitiligo in different parts who were not cured by other therapies visiting our hospital from March 2019 to December 2021 were enrolled as study subjects. They were treated by stem cell transplantation combined with 308‐nm excimer laser therapy. The treatment efficacy was observed and analyzed.ResultsAmong the 56 patients, 38 (67.85%) and 49 (87.5%) patients were cured at 6 and 12 months after treatment, respectively.ConclusionStem cell transplantation combined with 308‐nm excimer laser therapy for vitiligo achieves significant efficacy, with the cure rate far superior to that of other therapies for vitiligo. The therapy is worthy of popularization in the clinic.
Questionnaire survey regarding current status of minimally invasive surgery for endometrial cancer in Japan: A cross‐sectional survey for JSGOE members
Authors: Toyoshima Masafumi , Kobayashi Eiji , Terai Yoshito , Yamashita Tsuyoshi , Terao Yasuhisa , Nomura Hiroyuki , Asada Hironori , Hoshiba Tsutomu , Mikami Mikio , Mandai Masaki , Wada‐Hiraike Osamu , Akira Shigeo , Osuga Yutaka , Fujii Takuma ,   The Committee for Gynecologic Oncology Surgery, Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy (JSGOE)
Published: June 2023

AbstractAimMinimally invasive surgery (MIS) has been introduced as an alternative to more radical surgical procedures. The Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy conducted a cross‐sectional questionnaire survey to ascertain the status of MIS for endometrial cancer.MethodsThe survey was conducted between May 10 and June 30, 2022. The questionnaire included information on personal attributes, academic affiliations, qualifications, hysterectomies, and intraoperative procedures performed.ResultsThe total number of questionnaire respondents was 436 (9.2% of the membership). The hysterectomy methods and percentage performed were as follows: simple total hysterectomy (equivalent to benign surgery), 3%; simple total hysterectomy with care to avoid shaving the cervix, 31%; extended total hysterectomy, 48%; and modified radical hysterectomy, 15%. An analysis of hysterectomies performed using MIS for endometrial cancer by qualified gynecologists of endoscopy or board‐certified gynecologic oncologists showed a tendency not to choose simple total hysterectomy compared to the gynecologists who did not hold certification (p = 0.019, p = 0.045, and p = 0.010, respectively). Additionally, 67% of respondents did not use uterine manipulators, and 59% of the respondents did not perform lymph node dissection following the guidelines for treating endometrial cancer in Japan.ConclusionThis study provided the current status of MIS for endometrial cancer in Japan. The hysterectomy method, use of uterine manipulators, and criteria for omitting lymph node dissection were generally in agreement with the guidelines. Currently, an extra‐fascial simple hysterectomy, including at least not shaving the cervix, was a major method for early invasive endometrial cancer using MIS.
Rickettsial pathogens drive microbiota assembly in Hyalomma marginatum and Rhipicephalus bursa ticks
Authors: Maitre Apolline , Wu‐Chuang Alejandra , Mateos‐Hernández Lourdes , Piloto‐Sardiñas Elianne , Foucault‐Simonin Angélique , Cicculli Vincent , Moutailler Sara , Paoli Jean‐Christophe , Falchi Alessandra , Obregón Dasiel , Cabezas‐Cruz Alejandro 
Published: June 2023

AbstractMost tick‐borne pathogens (TBPs) are secondarily acquired by ticks during feeding on infected hosts, which imposes ‘priority effect’ constraints, as arrival order influences the establishment of new species in a microbial community. Here we tested whether once acquired, TBPs contribute to bacterial microbiota functioning by increasing community stability. For this, we used Hyalomma marginatum and Rhipicephalus bursa ticks collected from cattle in different locations of Corsica and combined 16S rRNA amplicon sequencing and co‐occurrence network analysis, with high‐throughput pathogen detection, and in silico removal of nodes to test for impact of rickettsial pathogens on network properties. Despite its low centrality, Rickettsia showed preferential connections in the networks, notably with a keystone taxon in H. marginatum, suggesting facilitation of Rickettsia colonisation by the keystone taxon. In addition, conserved patterns of community assembly in both tick species were affected by Rickettsia removal, suggesting that privileged connections of Rickettsia in the networks make this taxon a driver of community assembly. However, Rickettsia removal had minor impact on the conserved ‘core bacterial microbiota’ of H. marginatum and R. bursa. Interestingly, networks of the two tick species with Rickettsia have similar node centrality distribution, a property that is lost after Rickettsia removal, suggesting that this taxon drives specific hierarchical interactions between bacterial microbes in the microbiota. The study indicates that tick‐borne Rickettsia play a significant role in the tick bacterial microbiota, despite their low centrality. These bacteria are influential and contribute to the conservation of the ‘core bacterial microbiota’ while also promoting community stability.
Macrogenetics reveals multifaceted influences of environmental variation on vertebrate population genetic diversity across the Americas
Authors: Lawrence Elizabeth R. , Pedersen Eric J. , Fraser Dylan J. 
Published: June 2023

AbstractThe broad scale distribution of population‐specific genetic diversity (GDP) across taxa remains understudied relative to species diversity gradients, despite its relevance for systematic conservation planning. We used nuclear DNA data collected from 3678 vertebrate populations across the Americas to assess the role of environmental and spatial variables in structuring the distribution of GDP, a key component of adaptive potential in the face of environmental change. We specifically assessed non‐linear trends for a metric of GDP, expected heterozygosity (HE), and found more evidence for spatial hotspots and cold spots in HE rather than a strict pattern with latitude. We also detected inconsistent relationships between HE and environmental variables, where only 11 of 30 environmental comparisons among taxa groups were statistically significant at the .05 level, and the shape of significant trends differed substantially across vertebrate groups. Only one of six taxonomic groups, freshwater fishes, consistently showed significant relationships between HE and most (four of five) environmental variables. The remaining groups had statistically significant relationships for either two (amphibians, reptiles), one (birds, mammals), or no variables (anadromous fishes). Our study highlights gaps in the theoretical foundation upon which macrogenetic predictions have been made thus far in the literature, as well as the nuances for assessing broad patterns in GDP among vertebrate groups. Overall, our results suggest a disconnect between patterns of species and genetic diversity, and underscores that large‐scale factors affecting genetic diversity may not be the same factors as those shaping taxonomic diversity. Thus, careful spatial and taxonomic‐specific considerations are needed for applying macrogenetics to conservation planning.
Ecological traits of the franciscana dolphin (Pontoporia blainvillei) from the Late Pleistocene to the present days based on stable isotope analysis
Authors: Carrasco Thayara S. , de Lima Renan C. , da Mota Gabriel S. , Botta Silvina , Secchi Eduardo R. , Ribeiro Ana Maria , Ferigolo Jorge , Buchmann Francisco S. 
Published: June 2023

AbstractLate Pleistocene fossils from southern Brazil provide a unique opportunity to study the diet and habitat use of the extant franciscana dolphin (Pontoporia blainvillei) prior to human influence. Here, we subject 19 fossil and 21 contemporary specimens to stable carbon and oxygen isotope analysis (after first ruling out diagenesis via Fourier transform infrared spectroscopy). The two groups differ in their isotopic composition (PERMANOVA, p < .01), with fossils yielding more disparate δ13C values and recent samples more disparate δ18O values. Their isotopic niches show an overlap of ~20%, with that of the fossils being slightly wider (SEAc = 2.25‰2 versus 1.84‰2). We attribute these differences to impoverished modern fish communities and temporal changes in freshwater influx.
Decline of seagrass (Posidonia oceanica) production over two decades in the face of warming of the Eastern Mediterranean Sea
Authors: Litsi‐Mizan Victoria , Efthymiadis Pavlos T. , Gerakaris Vasilis , Serrano Oscar , Tsapakis Manolis , Apostolaki Eugenia T. 
Published: June 2023

Summary
The response of Posidonia oceanica meadows to global warming of the Eastern Mediterranean Sea, where the increase in sea surface temperature (SST) is particularly severe, is poorly investigated.
Here, we reconstructed the long‐term P. oceanica production in 60 meadows along the Greek Seas over two decades (1997–2018), using lepidochronology. We determined the effect of warming on production by reconstructing the annual and maximum (i.e. August) SST, considering the role of other production drivers related to water quality (i.e. Chla, suspended particulate matter, Secchi depth).
Grand mean (±SE) production across all sites and the study period was 48 ± 1.1 mg DW per shoot yr−1. Production over the last two decades followed a trajectory of decrease, which was related to the concurrent increase in annual SST and SSTaug. Annual SST > 20°C and SSTaug > 26.5°C was related to production decline (GAMM, P < 0.05), while the rest of the tested factors did not help explain the production pattern.
Our results indicate a persistent and increasing threat for Eastern Mediterranean meadows, drawing attention to management authorities, highlighting the necessity of reducing local impacts to enhance the resilience of seagrass meadows to global change threats.
Intraoperative transfusion practice and associated outcomes following neonatal surgery in a middle‐income country: A 5‐year single center retrospective review
Authors: Govender Kushal , Kemp Ellen , Motshabi Chakane Palesa 
Published: June 2023

AbstractBackgroundNeonates undergoing surgery are at greater risk of requiring packed red blood cell transfusion. Pediatric transfusion practices vary widely between countries and institutions, especially in the management of neonates.AimsThe aim of this study was to describe the use of intraoperative blood product transfusion during neonatal surgery in current clinical practice at our institution.MethodsA retrospective contextual, descriptive, and comparative study was conducted at Chris Hani Baragwanath Academic Hospital. A total of 1078 anesthetic records of neonates who underwent surgery from January 1, 2015 to December 31, 2019 were reviewed. Descriptive and inferential statistics were used to analyze the data.ResultsBlood products were transfused during 374 (34.7%) neonatal surgeries. Packed red blood cells, platelet concentrate, and fresh frozen plasma were administered during 327 (30.3%), 133 (12.3%), and 85 (7.9%) of the total 1078 surgeries, respectively. The median (interquartile range) volume of packed red blood cells, fresh frozen plasma, platelets, and clear fluid administered was 15 (10–21.8) mL/kg, 12.3 (10–23.5) mL/kg, 13.6 (10–20.5) mL/kg, and 19 (9.1–28.8) mL/kg, respectively. Very low weight, low preoperative hemoglobin, long total anesthetic time, emergency surgery, and major surgery were independently associated with blood product transfusion. Gestational age at birth, blood product transfusion, emergency surgery, and major surgery were independently associated with the composite adverse outcomes. The median preoperative hemoglobin was 11.8 g/dL.ConclusionsIntraoperative blood product transfusion occurred at a much higher rate with a high median pre‐transfusion hemoglobin compared to other studies.
Pediatric pyoderma gangrenosum with pulmonary involvement: A case report
Authors: Martín‐Zamora Ana Camila , Miranda‐Solis Lisa Natalia , Hidalgo‐Matlock Benjamin 
Published: June 2023

AbstractPyoderma gangrenosum is a rare disease in childhood. Extra‐cutaneous manifestations are uncommon in pyoderma gangrenosum, even more so in children, with only a few cases reported in the literature. We present the case of a pediatric patient with pyoderma gangrenosum and associated pulmonary involvement. In this case, the diagnosis was delayed leading to late initiation of therapy, emphasizing the importance of maintaining a high level of suspicion for this diagnosis.