bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengenalan Literasi Pasar Modal Sebagai Sarana Menabung Saham Bagi Siswa Smk Negeri 9 Kota Semarang
Authors: Sidiq Asah Wiari , Permanasari Rusdiana , Romadon Ahmad Sahri 
Published: August 2023

Pemahaman investment society sangat diperlukan dengan cara sosialisasi secara berkelanjutan yang melibatkan berbagai pihak agar pemahaman tentang literasi pasar modal kepada masyarakat dapat terus berkembang yaitu dengan mensosialisasikan kepada masyarakat terutama genarasi milenial bahwa investasi di pasar modal itu mudah, terencana, dan murah. Pengenalan literasi pasar modal sebagai sarana menabung saham bagi siswa SMK bertujuan untuk mengedukasi siswa sebagai generasi milenial agar melek terhadap literasi investasi pasar modal sehingga diharapkan siswa dapat tertarik mengikuti edukasi literasi investasi pasar modal selanjutnya tertarik dan berminat untuk menabung saham dengan membuka rekening pasar modal. Metode pelaksanaan kegiatan pengabdian kepada masyarakat berupa pemberian pembelajaran kepada mitra berupa ceramah atau pemberian materi kepada siswa di kelas tentang pengenalan literasi keuangan, pembelajaran pengenalan investasi pasar modal saham dan perlunya menabung sejak dini, selanjutnya diskusi dan tanya jawab mengenai literasi menabung saham serta evaluasi kegiatan. Hasil PKM menunjukan adanya peningkatan pengetahuan dan pemahaman mengenai literasi investasi pasar modal sebagai sarana menabung saham bagi siswa SMK Negeri 9 Kota Semarang.
Penerapan Model Megacita pada pembelajaran PPKn di SD Negeri Keputran 1 Yogyakarta
Authors: Kurniawan Arie 
Published: August 2023

Salah satu cara untuk meningkatkan peran aktif siswa dalam pembelajaran adalah dengan menggunakan model pembelajaran Think-Pair-Share. Berkaitan dengan hal tersebut, Balai Pengembangan Media Radio Pendidikan dan Kebudayaan mengembangkan Megacita suatu model pembelajaran PPKn yang mengadopsi Think-Pair-Share dengan tujuan meningkatkan kemampuan komunikasi, kolaborasi, berpikir kritis dan memecahkan masalah, serta kreativitas dan inovasi siswa. Penelitian ini bertujuan untuk mengetahui bagaimanakah penerapan Megacita pada pembelajaran PPKn di SDN Keputran 1 Yogyakarta mulai dari persiapan hingga hambatan yang dihadapi. Pendekatan yang digunakan dalam penelitian ini adalah kuantitatif dengan metode analisis data berupa deskriptif kuantitatif. Pada penerapan pertama, siswa masih belum paham dengan aktivitas pembelajaran yang harus mereka lakukan. Sebagian besar siswa juga masih pasif dalam proses diskusi, serta belum berani melakukan presentasi di depan kelas. Pada penerapan kedua, siswa lebih aktif dalam mengikuti pembelajaran, mereka semakin aktif dalam diskusi kelompok, dan sudah berani melakukan presentasi di depan kelas. Hambatan yang dihadapi dalam penelitian ini adalah kesiapan siswa dalam mengikuti pembelajaran, karena masih awam dengan Megacita. Dari penelitian ini dapat disimpulkan bahwa penerapan Megacita pada pembelajaran PPKn di SDN Keputran 1 Yogyakarta sudah berjalan sesuai dengan panduan. Tujuan dari pengembangan model Megacita juga sudah tercapai dengan meningkatnya kemampuan komunikasi, kolaborasi, memecahkan masalah dan inovasi siswa.
Bazı Şeker Sorgum ve Sorgum Sudan Otu Melezi Çeşitlerinde Farklı Biçim Uygulamalarına Göre Yaprak ve Sapların Mineral Element İçerilerindeki Değişimlerin Belirlenmesi
Authors: YILDIRIM Berk , ALATÜRK Fırat 
Published: August 2023

Bu araştırma şeker sorgum ve sorgum sudanotu melezi çeşitlerinin farklı biçim yüksekliklerine bağlı olarak yaprak ve sapların mineral element içeriklerini belirlemek amacıyla 2020-2021 yıllarında Çanakkale Onsekiz Mart Üniversitesi Ziraat Fakültesi araştırma alanında yürütülmüştür. Deneme bölünmüş parseller deneme desenine göre 4 tekrarlamalı olarak kurulmuş, ana parselleri çeşitler (Nutri Honey, Nutrima, M81-E ve Topper-76), alt parselleri ise hasat yükseklikleri (bitki boyu 30, 60, 90, 120, 150 cm olduğunda ve fizyolojik olum döneminde hasat) oluşturmuştur. Araştırmada 30 cm yükseklikte hasat edilen parseller toplamda 5 kez, 60 cm 4 kez, 90 cm 3 kez, 120 cm 3 kez, 150 cm 2 kez ve fizyolojik olum döneminde ise bir kez biçilmiştir. Araştırmada yaprak ve sapların bor, kadmiyum, nikel, kobalt, krom ve kurşun değerleri incelenmiştir. Çalışmadan elde edilen sonuçlara göre; bitkilerde büyümeye bağlı olarak yaprak ve sapların mikromineral (bor, kadmiyum, nikel, kobalt, krom ve kurşun) içeriklerinde düşüşler gerçekleşmiştir. Bu düşüş büyüme başlangıcından büyüme sonuna kadar hem sap hem de yapraklarda yaklaşık olarak borda %45-50, kadmiyumda %70-80, nikelde %79, kobaltta %70-75, kromda %54 ve kurşunda %54 civarında gerçekleşmiştir. Genel olarak yaprakların mikromineral içerikleri sap kısımlarından %8-50 oranında daha yüksek olmuştur. Sadece sap kısımların kobalt içerikleri yapraklardan daha yüksek çıkmıştır.
Yürütülen bu araştırmanın neticesinde otlatma ve kaba yem kaynağı olarak yetiştirilecek bu çeşitlerde otların mineral element içerikleri çeşitlerin benzer özellik gösterdiği fakat Nutrima ve M81-E çeşitlerinin daha fazla ön plana çıkarak yetiştirilmesi gereken çeşitler olabileceği önerilmektedir.
GROUPING PROVINCES IN INDONESIA BASED ON YOUTH DEVELOPMENT INDICATORS IN 2021
Authors: Nuralifian Muhamad Zidan , Nooraeni Rani 
Published: August 2023

Youth have a vital role in development. Indonesia has an uneven distribution of youth across provinces, with over half concentrated in Java. Many young people are also only sometimes in line with their qualities. Youth development was observed through youth development indicators in 2021. The method used is a multivariate method using cluster analysis. The cluster method applied in this research is hierarchy and partition. Based on internal and stability validity, the hierarchical method for five clusters and the number of clusters is the best. The hierarchical method that has the most significant agglomeration coefficient is complete linkage. There is one province with indicators that are very different from other provinces: Papua as cluster 1. Papua requires massive development in all aspects. Cluster 2 comprises Riau Island, Jakarta, the Special Region of Yogyakarta, Bali, and East Kalimantan. Cluster 3 consists of West Nusa Tenggara, Bengkulu, and Lampung. Cluster 4 consists of West Java, Banten, Central Java, Gorontalo, South Sumatra, and East Java. Meanwhile, cluster 5 consists of the remaining members, with the remaining 19 provinces having the most members.

Keywords: Youth Development Indicators, Cluster Analysis, Hierarchy, Partition
PEMBERDAYAAN INDUSTRI KECIL KERAJINAN ROTAN OLEH DINAS PERINDUSTRIAN DAN PERDAGANGAN DI DESA TELUK WETAN KECAMATAN WELAHAN KABUPATEN JEPARA PROVINSI JAWA TENGAH
Authors: Prihatini Juliati , Aldila Niken Aza 
Published: August 2023

Industri kecil kerajinan rotan menjadi salah satu sektor industri yang memiliki peran penting dalam pengembangan perekonomian di Kabupaten Jepara, terutama Desa Teluk Wetan yang merupakan kawasan sentra industri kecil kerajinan rotan. Penelitian ini bertujuan untuk menganalisis dan mendeskripsikan pemberdayaan, faktor penghambat serta upaya untuk mengatasi hambatan pada pemberdayaan industri kecil kerajinan rotan. Penelitian ini menggunakan metode kualitatif deskriptif. Teknik pengumpulan data dilakukan melalui wawancara, observasi dan dokumentasi. Teknik analisis data yang digunakan meliputi reduksi data, penyajian data dan verifikasi data. Hasil penelitian menunjukkan bahwa pemberdayaan industri kecil kerajinan rotan di Desa Teluk Wetan berdasarkan empat dimensi yang terdiri dari bina manusia, bina usaha, bina lingkungan dan bina kelembagaan telah dilaksanakan oleh Dinas Perindustrian dan Perdagangan Kabupaten Jepara melalui pembinaan secara langsung dengan memberikan pelatihan, bimbingan teknis, sosialisasi dan monitoring untuk meningkatkan kemampuan dan keterampilan serta memberikan modal usaha berupa peralatan produksi dan bantuan dalam promosi. Adapun faktor penghambat pemberdayaan industri kecil kerajinan rotan di Desa Teluk Wetan yaitu minimnya tenaga kerja yang terlatih, kurangnya pengembangan sarana prasarana dan keterbatasan dalam promosi. Upaya pada pemberdayaan industri kecil kerajinan rotan di Desa Teluk Wetan yaitu dengan meningkatkan kegiatan pelatihan kepada tenaga kerja, meningkatkan sarana dan prasarana serta memberikan bantuan promosi kepada industri kecil kerajinan rotan.

Kata Kunci: Industri Kecil, Kerajinan Rotan, Pemberdayaan
Antibacterial performance of a porous Cu-bearing titanium alloy by laser additive manufacturing
Authors: Xu Jiawei , Lu Yanjin , Pan Xiyun , Zhan Desong , Wang Qiang , Zhang Ning 
Published: August 2023

Porphyromonas gingivalis (P. gingivalis) is the most common species that causes peri-implantitis. It forms an irreversible dense biofilm and causes inflammation. A novel 3D-printed porous TC4-6Cu alloy was fabricated using selective laser melting (SLM) technology for the dental implant, which is anticipated to inhibit biofilm formation. We attempted to investigate the antibacterial ability and antibacterial mechanism of the 3D-printed porous TC4-6Cu alloy against P. gingivalis. This work used scanning electron microscopy (SEM) and laser confocal microscopy (CLSM) to detect the antimicrobial ability of the alloy against sessile P. gingivalis. The results indicated that the 3D-printed porous TC4-6Cu alloy could cause bacterial fragmentation and deformation. Plate antimicrobial counting experiments showed that the antibacterial rates of the alloy against adherent bacteria and planktonic bacteria after 24 h were 98.05% and 73.92%, respectively. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Cu2+ were tested to appraise the antibacterial property of the alloy against planktonic P. gingivalis. The relationship between the antibacterial mechanism of the alloy with oxidative stress was evaluated through ROS fluorescence intensity and protein leakage concentration. The results revealed that the alloy significantly eliminated adherent bacteria and inhibited biofilm formation. Moreover, 3D-printed porous TC4-6Cu alloy demonstrated significant bactericidal ability by inducing the production of reactive oxygen species (ROS), which could result in protein leakage from the bacterial cell membrane. This research may open a new perspective on the development and biomedical applications for dental implantation.
Bioethanol production from alkali-pretreated rice straw: effects on fermentation yield, structural characterization, and ethanol analysis
Authors: Ningthoujam Reema , Jangid Pankaj , Yadav Virendra Kumar , Sahoo Dipak Kumar , Patel Ashish , Dhingra Harish Kumar 
Published: August 2023

Current ethanol production technology has a dire need for efficient conversion of lignocellulosic biomass to fermentable sugars. The conversion requires pretreatment of the biomass, one of the most expensive steps, and thus it is quite necessary to identify the most cost-effective and high-efficiency conversion method. In this study, rice straw (RS) biomass was pretreated using 4% NaOH alkali, soaked for 4 h, and autoclaved for 30 min. The structural and morphological changes were examined using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM) analysis in both native and alkali-treated RS. The FTIR analysis revealed that native RS contains a considerable amount of lignin that was removed after the pretreatment process. The XRD pattern of the RS revealed an increasing crystallite size of the pretreated lignocellulosic biomass. The study of SEM clearly showed the distorted structure and surface porosity after the pretreatment process. Enzymatic hydrolysis efficiency was checked by comparing the commercial enzymes and microbial hydrolysis extracted from a fungal isolate. The best-reducing sugar yield obtained was 0.62 g/L, achieved at optimized conditions from the commercial enzymes. Fermentation efficiency was checked using the yeast isolate Saccharomyces cerevisiae in both the native and pretreated substrate, and the highest ethanol concentration (21.45%) was achieved using 20% w/v biomass loading, enzyme loading (2:1:1), and fermentation for a week at 30°C and pH 4.5. This concentration was higher than that of the untreated RS (3.67%). The ethanol thus produced was further checked for analysis by the 1H and 13C nuclear magnetic resonance (NMR) methods.
Cardiorespiratory fitness is associated with hippocampal resting state connectivity in women newly diagnosed with breast cancer
Authors: Lesnovskaya Alina , Ripperger Hayley S. , Donofry Shannon D. , Drake Jermon A. , Wan Lu , Poniatowski Alexa , Donahue Patrick T. , Crisafio Mary E. , Gilmore Alysha D. , Richards Emily A. , Grove George , Gentry Amanda L. , Sereika Susan M. , Bender Catherine M. , Erickson Kirk I. 
Published: August 2023

BackgroundBreast cancer and its treatment are associated with aberrant patterns of resting state functional connectivity (rsFC) between the hippocampus and several areas of the brain, which may account for poorer cognitive outcomes in patients. Higher cardiorespiratory fitness (CRF) has been associated with enhanced rsFC and cognitive performance; however, these associations have not been well studied in breast cancer. We examined the relationship between CRF, rsFC of the hippocampus, and cognitive performance among women newly diagnosed with breast cancer.MethodsThirty-four postmenopausal women newly diagnosed with Stage 0-IIIa breast cancer (Mage = 63.59 ± 5.73) were enrolled in a 6-month randomized controlled trial of aerobic exercise vs. usual care. During baseline assessments, participants completed functional brain imaging, a submaximal CRF test, and cognitive testing. Whole-brain, seed-based analyses were used to examine the relationship between CRF and hippocampal rsFC, with age, years of education, and framewise displacement included as covariates. Cognition was measured with a battery of validated neurocognitive measures, reduced to seven composite factors.ResultsHigher CRF was positively associated with greater rsFC of the hippocampus to a cluster within the dorsomedial and dorsolateral frontal cortex (z-max = 4.37, p = 0.003, cluster extent = 1,020 voxels). Connectivity within cluster peaks was not significantly related to cognitive factors (all ps &gt; 0.05).DiscussionCRF was positively associated with hippocampal rsFC to frontal cortex structures, comprising a network of regions commonly suppressed in breast cancer. Future longitudinal research is needed to explore whether baseline rsFC predicts long-term cognitive resilience in breast cancer.
Right ventricular contraction patterns in healthy children using three-dimensional echocardiography
Authors: Valle Christopher , Ujvari Adrienn , Elia Eleni , Lu Minmin , Gauthier Naomi , Hoganson David , Marx Gerald , Powell Andrew J. , Ferraro Alessandra , Lakatos Bálint , Tősér Zoltán , Merkely Béla , Kovacs Attila , Harrild David M. 
Published: August 2023

BackgroundThe right ventricle (RV) has complex geometry and function, with motion along three separate axes—longitudinal, radial, and anteroposterior. Quantitative assessment of RV function by two-dimension echocardiography (2DE) has been limited as a consequence of this complexity, whereas newer three dimensional (3D) analysis offers the potential for more comprehensive assessment of the contributors to RV function. The aims of this study were to quantify the longitudinal, radial and anteroposterior components of global RV function using 3D echocardiography in a cohort of healthy children and to examine maturational changes in these parameters.MethodsThree-dimensional contours of the RV were generated from a cohort of healthy pediatric patients with structurally normal hearts at two centers. Traditional 2D and 3D echo characteristics were recorded. Using offline analysis of 3D datasets, RV motion was decomposed into three components, and ejection fractions (EF) were calculated (longitudinal-LEF; radial-REF; and anteroposterior-AEF). The individual decomposed EF values were indexed against the global RVEF. Strain values were calculated as well.ResultsData from 166 subjects were included in the analysis; median age was 13.5 years (range 0 to 17.4 years). Overall, AEF was greater than REF and LEF (29.2 ± 6.2% vs. 25.1 ± 7.2% and 25.7 ± 6.0%, respectively; p &lt; 0.001). This remained true when indexed to overall EF (49.8 ± 8.7% vs. 43.3 ± 11.6% and 44.4 ± 10%, respectively; p &lt; 0.001). Age-related differences were present for global RVEF, REF, and all components of RV strain.ConclusionsIn healthy children, anteroposterior shortening is the dominant component of RV contraction. Evaluation of 3D parameters of the RV in children is feasible and enhances the overall understanding of RV function, which may allow improvements in recognition of dysfunction and assessment of treatment effects in the future.
Self-expanding vs. balloon-expandable transcatheter heart valves in small aortic annuli
Authors: Kornyeva Anastasiya , Burri Melchior , Lange Rüdiger , Ruge Hendrik 
Published: August 2023

BackgroundClinical consequences of prosthesis–patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR) is currently in the focus of clinical research. Patients with small aortic annulus are at higher risk to display PPM. Data on incidence and clinical consequences of PPM after TAVR with either balloon-expandable (BEV) or self-expanding (SEV) transcatheter heart valves in small aortic annulus are sparse.MethodsPatients with small aortic annulus (perimeter &lt; 72 mm or aortic annulus area &lt; 400 mm2) who underwent BEV or SEV with contemporary transcatheter heart valve types were identified from the institutional TAVR database. Propensity score matching was applied for imbalanced baseline characteristics between patients undergoing BEV or SEV. Echocardiography and clinical follow-up beyond 3 years was reported following VARC-3 recommendations. Primary endpoint was the incidence of pre-discharge PPM and its association with 3-year mortality.ResultsFrom a total of 507 patients with small aortic annulus, 192 matched patient pairs with SEV or BEV were identified. Mean age was 81 ± 7 (SEV) vs. 81 ± 6 (BEV) years (p = 0.5), aortic annulus perimeter was 69 ± 3 vs.69 ± 3 mm, (p = 0.8), annulus area was 357 ± 27 vs.357 ± 27 mm2 (p = 0.8), and EuroScore II was 5.8 ± 6.6 vs.5.7 ± 7.2 (p = 0.9). SEV resulted in less moderate (20% vs. 31%, p &lt; 0.001) and severe pre-discharge PPM (9% vs.18%, p &lt; 0.001) compared to BEV. At discharge (7 ± 4 vs. 12 ± 9 mmHg, p = 0.003) and at 1-year follow-up (7 ± 5 vs.13 ± 3 mmHg, p &lt; 0.001), SEV displayed lower mean gradients compared to BEV. Estimated survival after SEV was 85% (95% confidence interval (CI): 80%–90%) at 1 year, 80% (95% CI: 75%–86%) at 2 years, and 71% (95% CI: 65%–78%) at 3 years; estimated survival after BEV was 87% (95% CI: 82%–92%) at 1 year, 81% (95% CI: 75%–86%) at 2 years, and 72% (95% CI: 66%–79%) at 3 years, with no significant difference among the groups (p = 0.9) Body surface area (OR: 1.35, p &lt; 0.001), implantation of BEV (odds ratio (OR): 3.32, p &lt; 0.001), and the absence of postdilatation (OR: 2.16, p &lt; 0.001) were independent risk factors for any PPM. At 3 years, patients without PPM had a higher 3-year survival compared with patients with ≥moderate PPM (77% vs. 67%, p = 0.03).ConclusionBEV implantation in patients with small annulus was associated with a twofold higher incidence of pre-discharge severe PPM compared to SEV implantation. Survival at 3 years after TAVR was similar after BEV and SEV. However, patients with the absence of pre-discharge PPM had a higher 3-year survival compared to patients with ≥moderate PPM.
The Cenozoic spatiotemporal exhumation of the SE Tibetan Plateau: insight from the data mining and modeling of low-temperature thermochronology
Authors: Liu Fangbin , Wang Min , Liu Honghua , Ni Ran 
Published: August 2023

Introduction: The SE Tibetan Plateau is distinct from other margins due to its high elevation, long wavelength, and low relief. A clear understanding of the Cenozoic exhumation history of this region is the key to understanding the special geomorphological process and the associated mechanisms. Previous thermochronological studies have either focused on vertical sections or horizontal variations in the local regions. However, the spatiotemporal exhumation pattern of the entire SE Tibetan Plateau is enigmatic.Methods: In this article, we have compiled 1,202 thermochronological data using joint kernel density estimation (KDE) and linear inversion approaches to address the exhumation process.Results: The results reveal that at least six episodes of rapid cooling have occurred since the Cenozoic, which include ∼61–58 Ma, 38–35 Ma, 32–23 Ma, 18–13 Ma, 11–6 Ma, and 4–3 Ma. Furthermore, the entire SE Tibetan Plateau underwent spatially inhomogeneous exhumation throughout the main episodes.Discussion: We infer that all cooling episodes may be attributed to the lateral extrusion and continuous convergence between the Indian and Eurasian continents. Meanwhile, climate changes (e.g., intensified Asian summer monsoon and glacial processes) have also played a non-negligible role in shaping the landscape since the Miocene. Our results will provide new insights into geodynamic mechanisms of the exhumation processes throughout the whole SE Tibetan Plateau since the Cenozoic.
Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy
Authors: Markelic Milica , Stancic Ana , Saksida Tamara , Grigorov Ilijana , Micanovic Dragica , Velickovic Ksenija , Martinovic Vesna , Savic Nevena , Gudelj Andjelija , Otasevic Vesna 
Published: August 2023

IntroductionRecently, the involvement of ferroptotic cell death in the reduction of β-cell mass in diabetes has been demonstrated. To elucidate the mechanisms of β-cell ferroptosis and potential antidiabetic effects of the ferroptosis inhibitor ferrostatin-1 (Fer-1) in vivo, a mouse model of type 1 diabetes (T1D) was used.MethodsAnimals were divided into three groups: control (vehicle-treated), diabetic (streptozotocin-treated, 40 mg/kg, from days 1-5), and diabetic treated with Fer-1 (1 mg/kg, from days 1-21). On day 22, glycemia and insulinemia were measured and pancreases were isolated for microscopic analyses.ResultsDiabetes disturbed general parameters of β-cell mass (islet size, β-cell abundance and distribution) and health (insulin and PDX-1 expression), increased lipid peroxidation in islet cells, and phagocytic removal of iron-containing material. It also downregulated the main players of the antiferroptotic pathway - Nrf2, GPX4, and xCT. In contrast, Fer-1 ameliorated the signs of deterioration of β-cell/islets, decreased lipid peroxidation, and reduced phagocytic activity, while upregulated expression of Nrf2 (and its nuclear translocation), GPX4, and xCT in β-cell/islets.DiscussionOverall, our study confirms ferroptosis as an important mode of β-cell death in T1D and suggests antiferroptotic agents as a promising strategy for the prevention and treatment of diabetes