bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Relationship between Physical Activity and Body Composition Parameters in Office Workers: A Multi-Frequency Bioelectrical Impedance Analysis Approach
Authors: Yilmaz Dursun Alper , Uzuner Kubilay 
Published: May 2023

Abstract
This research aimed to determine the relationship between physical activity levels and body composition parameters in office workers. The study was carried out with 60 individuals who agreed to participate in the study and met the inclusion criteria, among the office workers who had sedentary jobs, at the Rector's Office of a university in the Eastern Region of the Republic of Turkey between June 2021 and January 2022. Informed Voluntary Consent Forms and the International Physical Activity Questionnaire were administered to participants. Body compositions were measured with the TANITA MC-780 Bioimpedance Device. The study found a positive relationship between lean body mass (kg), muscle mass in the right leg (kg), muscle mass in the left leg (kg), muscle mass in the right arm (kg), muscle mass in the left arm (kg), and trunk muscle (kg) with all Phase Angle (PhA) measures (p<0.05). Moreover, the study determined a correlation between lean mass in the right leg (kg), lean mass in the left leg (kg), lean mass in the right arm (kg), and lean mass in the left arm (kg) with vigorous activity scores (p<0.05). The study's results add to the existing literature on body composition values in individuals with prolonged sedentary behavior. It is a pioneering study that explores the relationship between segmental phase angles, body fat ratio, and physical activity levels. The findings suggest the need for further research in larger populations and different workgroups to validate these results and explore this relationship in more depth.
The Relationship Between Different Fatty Acids Intake and the Presence of Depression: A Population-Based Study
Authors: zheng xin , liu tong , Lin Shi-Qi , Liu Chen-An , Chen Yue , Ruan Guo-Tian , Ge Yi-Zhong , Xie Hai-Lun , Song Meng-Meng , Shi Jin-Yu , Wang Zi-Wen , Yang Ming , Liu Xiao-Yue , Zhang He-Yang , Deng Li , Shi Han-Ping 
Published: May 2023

AbstractBackground Depression is a common psychological disorder worldwide. Previous studies have explored the benefits of polyunsaturated fatty acids (PUFAs) in depression; however, few studies have focused on the association between different fatty acids and depression. Therefore, we explored the effect of the intake of different fatty acids on the risk of depression. Methods The study was based on the data from the 2005–2018 National Health and Nutrition Examination Survey (NHANES). We used a nutrient residual model and multivariate nutrient density model. We calculated the nutrient density and residual in men and women separately, and the fatty acid intake was divided into quartiles based on the sex distribution. The relationship between depression and different fatty acids was examined using logistic regression; furthermore, we explored the relationships in men and women. Results Monounsaturated fatty acids (MUFAs) and PUFAs, particularly n-3 and n-6 PUFAs, were associated with reduced odds ratios for depression, in contrast to total fatty acids (TFAs). The protective effect against depression of TFAs, MUFAs, PUFAs, and n-3 and n-6 PUFAs was stronger in women. Conclusion A higher intake of fatty acids, including MUFAs and PUFAs, may protect against depression, especially in women.
Developmental sex-specific transcriptomic patterns can be altered by transgenic expression of Uty
Authors: Rock Kylie D. , Folts Lillian , Zierden Hannah C. , Marx-Rattner Ruth , Leu Nicolae Adrian , Nugent Bridget M. , Bale Tracy L. 
Published: May 2023

Abstract
The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a (Utx), Kdm5c, and Ddx3x have far-reaching impacts on transcriptional control of phenotypic sex differences. Although the functionality of UTY (Kdm6c, the Y-linked homologue of UTX), has been supported by more recent studies, its role in developmental sex differences is not understood. Here we test the hypothesis that UTY is an important transcriptional regulator during development that could contribute to sex-specific phenotypes and disease risks across the lifespan. We generated a random insertion Uty transgenic mouse (Uty-Tg) to overexpress Uty. By comparing transcriptomic profiles in developmental tissues, placenta and hypothalamus, we assessed potential UTY functional activity, comparing Uty-expressing female mice (XX + Uty) with wild-type male (XY) and female (XX) mice. To determine if Uty expression altered physiological or behavioral outcomes, adult mice were phenotypically examined. Uty expression masculinized female gene expression patterns in both the placenta and hypothalamus. Gene ontology (GO) and gene set enrichment analysis (GSEA) consistently identified pathways focused on transcriptional regulation, immune response, and lipid homeostasis as biological processes associated with UTY. Interestingly, adult females expressing Uty gained less weight and had a greater glucose tolerance compared to wild-type male and female mice when provided a high-fat diet. Utilizing a Uty-overexpressing transgenic mouse, our results provide novel evidence as to a functional transcriptional role for UTY in developing tissues, and a foundation to build on its prospective capacity to influence sex-specific developmental and health outcomes.
Rationale for increasing oncological vigilance in relation to clinical findings in accessory parotid gland- observations based on 2192 cases of the Polish Salivary Network Database
Authors: Wierzbicka Małgorzata , Bartkowiak Ewelina , Pietruszewska Wioletta , Stodulski Dominik , Olejniczak Izabela , Markowski Jarosław , Piernicka-Dybich Aleksandra , Wierzchowska Małgorzata , Czech Joanna , Amernik Katarzyna , Chańko Alicja , Majszyk Daniel , Bruzgielewicz Antonii , Gazińska Patrycja , Mikaszewski Bogusław 
Published: May 2023

Abstract
The accessory parotid gland (APG, Vth level) differs in histological structure from main parotid tissue. This gives rise to the hypothesis, mirrored in clinical observations, that the representation of tumours is different than in the rest of the gland.
Aim
To analyse the epidemiological and histological differences of parotid tumours located in regions I-V, with particular emphasis on the distinctiveness of region V. To define the epidemiological factors that will indicate the risk of histological malignancy from clinically benign appearance.
Material and Method
Multicentre prospective study conducted between 2017-2021 by five Head and Neck Surgery University Departments, cooperating within the Polish Salivary Network Database 1929 patients (1048 women and 881 men) were included. The age, gender, patient occupation, place of inhabitation, tumour size, clinical features of malignancy, histology, facial nerve (FN) paresis were analysed for superficial lobe (I_II), deep lobe (III_IV) and with special regard to the tumours affecting region V.
Results
28 tumours were located exclusively in region V (1.45% total) and 72 tumours in region V with extension to neighbouring regions (3,7% total), characterized by significantly younger age and less frequent in retirees. In I-IV regions approximately 90% of tumours were benign, pleomorphic adenoma (PA) and Whartin tumour (WT) predominance. In region V PA exceed 75% but TW were casuistic (2/28). Incidence of malignancies in region V was 40% but clinical signs of malignancy were evident only in tumours>4 cm or in the presence of FN paresis. In 19% of patients with a benign appearance, imaging revealed malignancy, however in 38% of patients, the result remained false negative both in terms of clinical and radiological features of malignancy. Logistic regression models in 28 patients with tumour located exclusively in region V vs 1901 other patients and the in 100 patients with V extension vs 1829 other patients showed no clinical symptoms of malignancy bind with final malignant tumor histology as a single variable or in combination with other variables. The logistic regression models obtained in this study shows strong linkage between tumor location and predictors (age, male gender and tumor diameter) and aimed to act as a good classifier.
Conclusion
Despite the very clear image of the mid-cheek tumour, easily accessible in palpation and ultrasound examination, it is necessary to improve the oncological vigilance and preoperative patient preparation.
A cardiac fibrosis determinative factor, Meox1, blocks direct reprogramming of cardiac myofibroblasts to cardiomyocyte-like cells
Authors: Yang Chunyan , Wu Jingdong , Zhu Shaoqi , Yang Xiaochun , Yang Yang , Tao Yanmeng , Zhou Bin , Tang Chao , Zhao Yang 
Published: May 2023

Abstract
Direct reprogramming of cardiac fibroblasts (CFs) into induced cardiomyocyte-like cells (iCMs) is a promising regenerative medicine therapy for myocardial infarction (MI) patients. CFs are activated and transition to myofibroblasts (MFs) after MI, which are abundant in the injured area. However, MFs show lower cardiac reprogramming efficiency. We identified Meox1, a TGF-β1 downstream transcription factor, which involved in cardiac fibrosis, as a barrier to cardiac reprogramming. In MFs induced with MGT (Mef2c, Gata4 and Tbx5) or MGT plus Myocd (MGTM), Meox1 knockdown results in significant increase in reprogramming efficiency. RNA-seq and CHIP-seq analysis showed the function of Meox1 in stabilizing a fibrosis-associated transcriptomic program. Furthermore, mutations disrupting the MEOX1 DNA binding domain or fusing it to a transcriptional repressor domain attenuate its inhibition of cardiac reprogramming. Dual recombinase tracing showed that iCM reprogramming efficiency is higher and cardiac function can be restored after MI with Meox1 knockdown. Finally, we found that Meox1 knockdown improved reprogramming efficiency in human CFs. These findings provide a potent target that can be further developed for direct cardiac regeneration.
Remotely imaging seismic ground shaking via large-N infrasound beamforming
Authors: Anderson Jacob F. , Johnson Jeffrey B. , Mikesell Thomas Dylan , Liberty Lee M. 
Published: May 2023

Abstract
Seismic ground motion creates low-frequency atmospheric sound (infrasound) that is detectable at remote sensor arrays. However, earthquake infrasound signal analysis is complicated by interference between multiple waves arriving at sensors simultaneously, reducing the accuracy and detail of ground motion detection. Here we show that individual waves in complicated wavefields can be resolved by recording infrasound on large-N arrays and processing with CLEAN beamforming. Examining both a local (M3.5, purely tropospheric infrasound propagation) and regional earthquake (M6.5, upper-atmospheric returns), we detect infrasound from tens of km away and up to several hundred km away respectively. Source regions span arcs of approximately 90°, indicating that although detection bias does occur (most likely from atmospheric winds) the recorded infrasound sources are widely dispersed and not simply epicentral. Infrasound-based remote detection of ground motion over wide areas can complement point measurements by seismometers and spur innovations in earthquake research and real-time hazard monitoring.
Differences in the Prevalence and Risk Factors of Suicidal Behavior Between Cargivers and People with Dementia: A Systematic Review
Authors: Abdullah Mohammad Farris Iman Leong Bin , Shari Nurul Izzah , Mohamad Mohd Afifuddin 
Published: May 2023

Abstract
Background: Caregivers of dementia patients and people with dementia are prone to exhibit suicidal behaviors due to difficulty to adjust to the initial caregiving role and emotional disturbance resulting from deterioration of functioning, respectively. This systematic review: [1] explored the prevalence and risk factors of suicidal behavior, and [2] assessed the differences in the prevalence and risk factors of suicidal behavior between caregivers of dementia patients and people with dementia.
Methods: A comprehensive literature search for research articles was carried out from 1950 to December 2022 using major databases, such as Google Scholar, Web of Science, PubMed, Scopus, PsycINFO, EMBASE, Cochrane Library, and Medline.
Results: A total of 38 research articles were selected for review. A total of 12 research articles revealed that the prevalence of suicidal behavior among caregivers ranged from 4.7% to 26%. However, the risk of suicidal behavior among people with dementia was inconsistent as only 15 out of 26 selected studies reported risk of suicidal behavior among people with dementia. The risk factors associated with suicidal behavior among caregivers of dementia patients could be both self-related and care receiver-related factors, whereas risk factors in dementia patients are self-related factors. Moreover, caregivers with high resilience may bounce back to maintain their initial psychological functioning prior to caregiving and safeguard their mental well-being. Contrastingly, resilience among people with dementia was not reported, but greater cognitive decline which impaired their ability to carry out complex act and planning may lower their suicidal risk. Finally, assessment of risk of bias indicated that 95% of the selected studies had unclear risk.
Conclusion: Psychosocial interventions which are effective to enhance resilience should be provided to caregivers in the management of psychological impact of the caregiving role for dementia patients. In addition, we recommend evaluation of suicidal risk on dementia patients to be carried out in the early phase of dementia when cognitive decline is less severe. However, as majority of selected studies had unclear risk of bias, future studies with improve methodology are warranted to confirm our study findings.
Characteristics of Magnetic Elastic Abrasive Particles and Their Effect on Tool Passivation
Authors: Zhao Xuefeng , Yuan Yin , You Ke , Yin XiaoLong 
Published: May 2023

Abstract
Magnetic elastic abrasive particles are a new type of particle that combine the characteristics of magnetic abrasive particles and elastic abrasive particles by embedding magnetic media and abrasive particles in a particular proportion into a flexible polymer to form particles with a specific shape. First, a method for preparing magnetic elastic abrasive particles is proposed. A representative micro-unit model of magnetic elastic abrasive particles is established using 3DMAX software. The finite element software ABAQUS is used to analyze the micromechanical properties of magnetic elastic abrasive particles with silicon carbide (SiC) and alumina (Al2O3) particles as the abrasive phase, respectively. Secondly, based on the characteristics of double disk magnetic force passivation of magnetic elastic abrasive particles, a method is proposed to predict the life of magnetic elastic abrasive particles by predicting the surface roughness of the tool edge. The effects of particle size and abrasive phase on the wear and life of magnetic elastic abrasive particles are studied experimentally. Finally, the magnetic field force is analyzed, and a mathematical model of material removal for magnetic elastic abrasive particles is established based on the characteristics of the mixing phase. The effects of particle size and abrasive degree on material removal volume are studied, and the influence of magnetic elastic abrasive particle size on tool passivation is experimentally analyzed. A comparison is made with the vertical rotary passivation method. The superiority of the magnetic elastic abrasive particle passivation method is verified by examining the passivated tool's edge profile, surface roughness, and service life.
Machine learning algorithm predicts fibrosis-related blood diagnosis markers of intervertebral disc degeneration
Authors: Zhao Wei , Wei Jinzheng , Ji Xinghua , Jia Erlong , Li Jinhu , Huo Jianzhong 
Published: May 2023

Abstract
Background
The fibrosis of intervertebral disc cells has been proven to be relevant to intervertebral disc degeneration (IDD). This study is devoted to screening fibrosis-related diagnostic genes for IDD patients.
Results
CEP120, SPDL1 were screened as diagnostic genes. NK cells, neutrophils, and MDSC represented significantly different proportions between IDD and control samples. It was indicated that AC144548.1 could regulate the expression of SPDL1 and CEP120 by combining hsa-miR-5195-3p and hsa-miR-455-3p respectively. Additionally, TFs FOXM1, PPARG, ATF3 could regulate the transcription of SPDL1 and CEP120. A total of 56 drugs were predicted to target drug prediction. The down-regulations of SPDL1 and CEP120 were validated as well.
Conclusion
This study identified two fibrosis-related diagnostic genes for IDD patients and found their potential regulatory network and target drugs, which could theoretical basis and reference for further study of IDD in the fibrosis-related gene area.
Present Geothermal Fields in the Santos Basin, Brazil
Authors: Zuo Guoping , Wang Hongping , Lan Lei , Zhang Yonggang , Zuo Yinhui , Yang Liu , Wang Chaofeng , Pang Xu , Song Xu , Yang Meihua 
Published: May 2023

Abstract
The Santos Basin, located in the southeastern waters of Brazil, is a passive continental margin basin with the most abundant deepwater petroleum resources in the world discovered to date. However, few studies have been conducted on the present geothermal fields of the Santos Basin, which severely restricts the oil and gas resource evaluation of the basin. This study first utilizes 35 temperature data from 16 post-salt drilling wells and 370 temperature data from 31 pre-salt drilling wells to calculate the post-salt and pre-salt geothermal gradients and terrestrial heat flows in the Santos Basin. Then, the basin simulation software BasinMod 1D is used to quantitatively evaluate the impacts of salt rock sedimentation on the present geothermal fields and the maturity of pre-salt hydrocarbon source rocks. The results demonstrate that the present post-salt geothermal gradient in the Santos Basin is 2.20–3.97 ℃/100m, with an average value of 2.99 ℃/100m, and the post-salt terrestrial heat flow is 54.00-97.32 mW/m2, with an average value of 73.36 mW/m2, while the present pre-salt geothermal gradient is 2.21–2.95 ℃/100m, with an average value of 2.53 ℃/100m, and the pre-salt terrestrial heat flow is 61.85–82.59 mW/m2, with an average value of 70.69 mW/m2. These values are characteristic of a low-temperature geothermal fields in a zone with a stable structure. The sedimentation of the salt rock causes a decrease in the temperature of the pre-salt strata, which inhibits pre-salt hydrocarbon source rock maturity, with an inhibition rate of up to 1.32%. The inhibition degree decreases with increasing salt rock thickness. At the same time, the salt rock thickness is positively correlated with the present surface heat flow. The unique distribution of the salt rock and related salt structures lead to present terrestrial heat flow differences among different structural units in the basin. This study is of great significance for evaluating and exploring the pre-salt oil and gas resources in the Santos Basin.
Enhancing urban resilience versus contagious diseases: An efficient clustering method for urban transportation networks
Authors: Gorji Mohammad-Ali , Boushehri Seyed Nader Shetab 
Published: May 2023

Abstract
Lockdowns in urban scale are shown to be a last resort during pandemics. Despite the effectiveness of this strategy in preventing the spread of disease, the economic necessities of citizens and the social and psychological difficulties created during lockdowns are severe challenges to their long-term implementation. Thus, officials pursue versions of lockdown that promote health-livelihoods dichotomy at the same time. This paper proposes a method for clustering cities such that, at the same time, the essential connections among residents and their basic sustenance (grocery and medical services) are maintained, and social bubbling is warranted. Clusters of a network are set of nodes densely connected to each other and sparsely connected to the rest of the network. Because the network is relatively sparse on the borders of clusters, they are cost-effective places for implementing control strategies such as regional lockdowns. As our clustering method is hierarchical, it allows different levels of clustering. As the number of clusters increases, the limitations get stricter, the physical range of trips gets shorter, and more social distancing is applied. The lower number of clusters results in more freedom but may result in higher virus spread risk. We apply our method to a large city (Isfahan, Iran). We assign a daily origin-destination matrix to our real network and use daily traffic flow among pairs of nodes as the proxy for their correlation and interaction. Results show that setting the minimum number of clusters (i.e., four) would ban 25% of daily non-work trips while increasing the number of clusters to 27 would ban 70% of those trips.
The practical and educational value of scleral buckling with chandelier illumination
Authors: Takesue Atsuhide , Yokoyama Toshiyuki , Koiwa Chihiro , Mayumi Miyako , Kasuga Toshimitsu , Ooya Hiroki 
Published: May 2023

Abstract
Purpose: To compare the surgical results in cases of primary rhegmatogenous retinal detachments between standard scleral buckling (SSB) and scleral buckling with chandelier illumination (SBC) and to analyze the differences in SBC surgical results between an experienced ophthalmologist and inexperienced ophthalmologists.
Methods: Consecutive surgical case series of 155 eyes that underwent scleral buckling were retrospectively reviewed and divided into four groups: SSB performed by an experienced ophthalmologist (n=54), SBC performed by an experienced ophthalmologist (n=52), SBC performed by inexperienced ophthalmologists (n=40), and SSB performed by inexperienced ophthalmologists (n=9). Then these four groups were compared.
Results: No significant differences were observed between SSB and SBC procedures both performed by the experienced ophthalmologist with regard to demographics, preoperative findings, contents of the surgery, intraoperative complications, retinal reattachment, postoperative findings and postoperative complications. Between SBC performed by the experienced ophthalmologist and SBC performed by the inexperienced ophthalmologists, no significant differences were found regarding intraoperative complications, retinal reattachment, postoperative findings and postoperative complications. Between SSB and SBC procedures both performed by the inexperienced ophthalmologist, a significant difference was found regarding intraoperative complications.
Conclusion: There were no significant differences in surgical results between SSB and SBC when both were performed by the experienced ophthalmologist. In addition, the surgical results were equal between the experienced ophthalmologist and the inexperienced ophthalmologist as far as SBC was concerned. Learning scleral buckling skills by using SBC is a reasonable course of action for inexperienced ophthalmologists.