bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does parental phubbing aggravates adolescent sleep quality problems?
Authors: Ding Qian , Dong Siwei , Zhang Yongxin 
Published: February 2023

ObjectiveBased on the theoretical model for the “stress–sleep” relationship, this study investigated the impact of parental phubbing on adolescent sleep quality problems and a moderated mediation mechanism.MethodsA total of 781 adolescents was surveyed using the Chinese version of Parental Phubbing Scale, the Ultra-brief Screening Scale for Depression and Anxiety Scale, the Self-Control Questionnaire for Chinese children, and the Chinese version of Pittsburgh Sleep Quality Index Scale.ResultsParental phubbing and negative emotions were significantly and positively correlated to sleep quality problems, but self-control was not correlated to sleep quality problems. Parental phubbing directly influenced sleep quality problems and also indirectly influenced sleep quality problems through the mediating effect of negative emotions. Moreover, self-control played a moderating role in the path of parental phubbing affecting negative emotions. That is, the effect was more significant for adolescents low in self-control relative to those high in self-control.ConclusionParental phubbing is a risk factor for adolescent sleep quality problems. This study is the first to demonstrate empirical evidence for the relationship between parental phubbing and sleep quality problems.
Relationships between parental responsive feeding and infant appetitive traits: The moderating role of infant temperament
Authors: Liu Yan , Kong Yan , Li Zhihui , Zhang Guanghua , Wang Lin , Yu Guiling 
Published: February 2023

IntroductionBetween the ages of 6 and 12 months is a crucial stage for children to develop appetitive self-regulation. Evidence suggests that a combination of parental responsive feeding and infant temperament (surgency, effortful control, negative affect) shapes infant appetitive traits (food approach, food avoidance). There is a need for research to explore these relationships, in order to provide guidance for the design of an effective intervention to improve appetitive traits. The objective of the current study was to explore the moderating role of infant temperament in the relationship between parental responsive feeding and infant appetitive traits.MethodsA total of 616 questionnaires, measuring parental responsive feeding, infant appetitive traits, and infant temperament, were collected from parents with infants aged 6–12 months.ResultsResults revealed that responsive feeding was associated with both food approach and food avoidance. Furthermore, only lower levels of surgency significantly moderated the relationship between responsive feeding and food approach, while responsive feeding was associated with food avoidance irrespective of infant temperament.DiscussionThese findings suggest that a strategy embedding responsive feeding interventions should be adopted to reduce infant food avoidance and low-surgent infant food approach, and interventions that are tailored toward food approach for infants with effortful control, negative affect, or higher levels of surgency should be further sought.
Employment relationships of Chinese expatriates: A multi-foci perspective of psychological contract
Authors: Wang Xiao , Wang Siming , Zhu Mengmei 
Published: February 2023

IntroductionResearch into expatriation has made a great contribution to the understanding of issues surrounding international human resource management. However, academic discussion around the subject of expatriate management remains Western-centred, neglecting the use of expatriate staffing in multinational corporations (MNCs) from Eastern countries. By adopting a multi-foci perspective of the psychological contract, the overall objective of this research is to explore the content of Chinese expatriates’ psychological contracts.MethodsThis paper draws on the findings of an organisational case study and is based on semi-structured interviews with 14 expatriates.ResultsThe findings provide evidence that individuals have multiple simultaneous psychological contracts, each with a different focus. The contracts held by the Chinese expatriates in this sample contain predominately balanced contract beliefs, which contrast sharply to what the other authors find to be salient beliefs (e.g., transactional contract beliefs) for expatriates based on Western samples. Importantly, the most frequently listed exchange partners by the pre-departure expatriates were line managers and department managers in headquarters; individuals appreciate the respective role of each party in shaping their aspects of work conditions whilst acknowledging the simultaneous existence of such influences.DiscussionThis paper has implications for expatriate management in the following ways. First, managers are encouraged to appreciate the role of multiple parties in shaping expatriates’ psychological contracts. This helps to enhance management’s understanding on the motives and demands of those expatriates. Second, policies of support and contact would aid feelings of integration. Finally, more attention should be paid to planning expatriate career prospects.
Effective interventions for gaming disorder: A systematic review of randomized control trials
Authors: Chen Yuzhou , Lu Jiangmiao , Wang Ling , Gao Xuemei 
Published: February 2023

ObjectiveTo identify effective intervention methods for gaming disorder (GD) through a rigorous assessment of existing literature.MethodsWe conducted a search of six databases (PubMed, Embase, PsycINFO, CNKI, WanFang, and VIP) to identify randomized controlled trials (RCTs) that tested GD interventions, published from database inception to December 31, 2021. Standardized mean differences with 95% confidence intervals were calculated using a random effects model. Risk of bias was assessed with the Risk of Bias 2 (RoB 2) tool.ResultsSeven studies met the inclusion criteria. Five interventions were tested in these studies: group counseling, craving behavioral intervention (CBI), transcranial direct current stimulation (tDCS), the acceptance and cognitive restructuring intervention program (ACRIP), and short-term cognitive behavior therapy (CBT). Four of the five interventions (the tDCS was excluded) were found to have a significant effect on GD. The results of the quality assessment showed that the included studies had a medium to high risk in the randomization process and a medium to high risk of overall bias.ConclusionRigorous screening identified that four interventions are effective for GD: group counseling, CBI, ACRIP, and short-term CBT. Additionally, a comprehensive review of the literature revealed that improvements could be made in the conceptualization of GD, experimental design, sample representativeness, and reporting quality. It is recommended that future studies have more rigorous research designs and be based on established standards to provide more credible evidence to inform the development of GD interventions.
Inpatient post-COVID-19 rehabilitation program featuring virtual reality—Preliminary results of randomized controlled trial
Authors: Rutkowski Sebastian , Bogacz Katarzyna , Rutkowska Anna , Szczegielniak Jan , Casaburi Richard 
Published: February 2023

BackgroundNumerous recommendations from pulmonary scientific societies indicate the need to implement rehabilitation programs for patients after COVID-19. The aim of this study was to propose an innovative comprehensive intervention based on a hospital-based pulmonary rehabilitation program for individuals with post-acute sequelae of COVID-19.MethodsIt was decided to evaluate two forms of hospital rehabilitation: traditional and one provided through virtual reality. Preliminary results are based on a group of 32 patients (20 female and 12 male), of average age 57.8 (4.92) years in the period of 3–6 months after the initial infection. Primary outcomes included analysis of lung function, exercise performance and stress level. A 3-week, high-intensity, five-times per week pulmonary rehabilitation program was designed to compare the effectiveness of a traditional form with a VR-led, novel form of therapy.ResultsThe analysis of the results showed a statistically significant improvement in both groups with regard to exercise performance expressed as 6MWT distance. Moreover, a statistically significant decrease in dyspnoea levels following the 6MWT was also noted in intergroup comparison, but the between-group comparison revealed non-statistically significant changes with low effect size. Regarding lung function, the analysis showed essentially normal lung function at baseline and a non-statistically significant improvement after the completion of the rehabilitation program. The analysis of the stress level showed a statistically significant improvement in both groups within the inter-group comparison, yet the between-group comparison of deltas values showed a non-significant difference with low effect size.ConclusionA 3-weeks inpatients pulmonary rehabilitation program led to improvement of the exercise performance of people with post-acute sequelae of COVID-19, but not lung function. Furthermore, the program was shown to reduce patients' stress levels. A comparison of the traditional form of rehabilitation to the novel form using VR, shows similar effectiveness in terms of exercise performance and stress levels.
An online method to monitor hand muscle tone during robot-assisted rehabilitation
Authors: Ranzani Raffaele , Chiriatti Giorgia , Schwarz Anne , Devittori Giada , Gassert Roger , Lambercy Olivier 
Published: February 2023

Introduction:Robot-assisted neurorehabilitation is becoming an established method to complement conventional therapy after stroke and provide intensive therapy regimes in unsupervised settings (e.g., home rehabilitation). Intensive therapies may temporarily contribute to increasing muscle tone and spasticity, especially in stroke patients presenting tone alterations. If sustained without supervision, such an increase in muscle tone could have negative effects (e.g., functional disability, pain). We propose an online perturbation-based method that monitors finger muscle tone during unsupervised robot-assisted hand therapy exercises.Methods:We used the ReHandyBot, a novel 2 degrees of freedom (DOF) haptic device to perform robot-assisted therapy exercises training hand grasping (i.e., flexion-extension of the fingers) and forearm pronosupination. The tone estimation method consisted of fast (150 ms) and slow (250 ms) 20 mm ramp-and-hold perturbations on the grasping DOF, which were applied during the exercises to stretch the finger flexors. The perturbation-induced peak force at the finger pads was used to compute tone. In this work, we evaluated the method performance in a stiffness identification experiment with springs (0.97 and 1.57 N/mm), which simulated the stiffness of a human hand, and in a pilot study with subjects with increased muscle tone after stroke and unimpaired, which performed one active sensorimotor exercise embedding the tone monitoring method.Results:The method accurately estimates forces with root mean square percentage errors of 3.8% and 11.3% for the soft and stiff spring, respectively. In the pilot study, six chronic ischemic stroke patients [141.8 (56.7) months after stroke, 64.3 (9.5) years old, expressed as mean (std)] and ten unimpaired subjects [59.9 (6.1) years old] were tested without adverse events. The average reaction force at the level of the fingertip during slow and fast perturbations in the exercise were respectively 10.7 (5.6) N and 13.7 (5.6) N for the patients and 5.8 (4.2) N and 6.8 (5.1) N for the unimpaired subjects.Discussion:The proposed method estimates reaction forces of physical springs accurately, and captures online increased reaction forces in persons with stroke compared to unimpaired subjects within unsupervised human-robot interactions. In the future, the identified range of muscle tone increase after stroke could be used to customize therapy for each subject and maintain safety during intensive robot-assisted rehabilitation.
Prolactinomas in adolescent and elderly patients—A comparative long-term analysis
Authors: Andereggen Lukas , Tortora Angelo , Schubert Gerrit A. , Musahl Christian , Frey Janine , Luedi Markus M. , Mariani Luigi , Beck Jürgen , Christ Emanuel 
Published: February 2023

ObjectivesProlactinomas represent the most common type of secreting pituitary adenomas, yet are rarely encountered in adolescent-onset (AO; i.e. &lt;18 years) or elderly-onset (EO; i.e. ≥65 years) cohorts. As a result, it is not clear whether long-term strategies should be focused differently at both age extremes when comparing their therapeutic outcomes. We aimed at investigating long-term endocrinological outcomes, looking for differences between the two cohorts and evaluating the dependence on continued dopamine agonist (DA) therapy.MethodsRetrospective cross-sectional comparative study analyzing prolactinoma patients with a follow-up of ≥4 years. Clinical, radiological and biochemical characteristics were assessed at diagnosis and last follow-up. Longitudinal endocrinological outcomes between groups of extreme ages (i.e. AO and EO) and middle age (i.e. ≥18 years to 65 years) were compared. Independent risk factors for long-term dependence on DAs were calculated.ResultsFollow-up at ≥4 years was recorded for 108 prolactinoma patients; 10 patients with AO and 10 patients with EO. Compared to AO patients, EO patients were predominantly men (p = 0.003), and presented with significantly higher prolactin (PRL) levels (p = 0.05) and higher body mass index (p = 0.03). We noted a significant positive correlation between patients' PRL values and their age (r = 0.5, p = 0.03) or BMI (r = 0.6, p = 0.03). After a median follow-up of 115 months, remission was noted in 87 (83%) patients; 9 (90%) in AO patients, and 7 (70%) in EO patients (p = 0.58). Continuation of DAs was required in 4 patients (40%) with AO and 7 patients (70%) with EO (p = 0.37). Patients with elderly-onset were an independent predictor of long-term dependence on DAs (HR 2.8, 95% CI 1.1-7.2, p = 0.03).ConclusionsLong-term control of hyperprolactinemia and hypogonadism does not differ between members of the AO and EO cohorts, and can be attained by the majority of patients. However, adjuvant DAs are often required, independent of the age of onset. Considering the clinical significance of persistent DA therapy for the control of hyperprolactinemia in many patients at both extremes of age, long-term monitoring may become recommended, in particular in patients with elderly-onset.
Congenital transmission of Neospora caninum in wild ungulates and foxes
Authors: Zanet Stefania , Poncina Manuela , Ferroglio Ezio 
Published: February 2023

IntroductionNeospora caninumis one of the main causes of abortion in cattle. In wildlife, the occurrence and relevance of vertical infection have not been yet clearly evaluated. The aim of this study was to verify the possibility of vertical transmission ofN. caninumin three wild species extensively distributed in Europe, namely roe deerCapreolus capreolus, wild boarSus scrofaand red foxVulpes vulpes.MethodsA total of 190 fetuses (72 wild boars, 67 foxes and 51 roe deer) from 61 females were included in the study. All animals, which were either found dead or culled within selective control plans in North-western Italy, were tested, in parallel by PCR on central nervous system, skeletal muscle and kidney.Results and discussionThe efficiency of vertical transmission in the three target species was of 87.5% (95% CI 69.00–95.66).
Backcrossing with Marker Assistance to Introduce Broad-Spectrum Bacterial Leaf Blight Resistance in the Malaysian Elite Variety MR297
Authors: Aljumaili Saba Jasim , Rafii Mohd Y. , Sakimin Siti Zaharah , Ahmad Khairulmazmi , Al-Jumaily Abdulmajeed 
Published: February 2023

A significant part of marker-assisted backcross breeding (MABB) is recurrent parent genome recovery (RPGR). The purpose of this study was to introduce MABB-mediated resistance genes against numerous bacterial leaf blight (BLB) pathogens. Here, we examine the introgression of four Xoo resistance genes to the high-yielding Malaysian MR297 lineage Xa21, xa13, xa5, and Xa4 from the IRBB60 lineage. To accomplish both foreground and background selection, we employed polymorphic functional linked markers to target genes and simple sequence repeat (SSR) markers. We used 83 of the 475 authorized polymorphic microsatellite markers to determine the proportion of RPGR in the chosen lines. According to the data, the RPGR at BC1F1, BC2F1, and BC2F2 are 81.94, 92.30, and 95.04%, respectively. Incorporating the four BLB resistance genes into the newly created lines would result in long-lasting and comprehensive protection against BLB. Therefore, a resistant gene may be introduced into a population more quickly with MABB than through conventional breeding. All ten lines tested showed a significant level of resistance to BLB, with three lines displaying very high levels of resistance. Consequently, it was recommended that new lines should be used to produce commercially viable rice varieties.
Cultivar Susceptibility to Olive Knot Disease and Association with Endophytic Microbiota Community
Authors: Licciardello Grazia , Mosca Alexandros , Di Silvestro Silvia , Puglisi Damiano , Russo Maria Patrizia , Catara Vittoria , Caruso Paola 
Published: February 2023

Olive knot disease (OKD) induced by the bacterium Pseudomonas savastanoi pv. savastanoi seriously affects olive production in the Mediterranean basin. Nowadays, the only strategies to control the disease are pruning and the application of cupric products. An essential strategy to enhance protection is represented by the identification of resistant cultivars, which represents a crucial opportunity for future investments and breeding. We undertook a three-year-long survey at the International Olive Germplasm Collection of “Villa Zagaria” (Sicily, Italy) on thirty-six Sicilian cultivars that were monitored for symptom development. Cultivars with different levels of susceptibility were divided into five clusters. Moreover, in order to investigate possible interactions with endophytic microbial communities, two cultivars with contrasting susceptibilities, Zaituna (highly resistant) and Giarraffa (highly susceptible), were selected for an amplicon-based metagenomic analysis. Distinct endophytic communities colonized the two cultivars, suggesting an interaction between the resident bacterial community and the pathogen. Significantly higher bacterial richness was detected in the shoots of the susceptible cv. Giarraffa, although it had lower diversity. The opposite trend was observed for fungal communities. Among the microbes resulted to be enriched in cv. Giarraffa, it is important to underline the presence of Pseudomonas among the bacterial genera, and Alternaria, Neofusicoccum, Epicoccum, Ascochyta, and Elsinoe among the fungal genera, which include many species often described as plant pathogens and biocontrol agents. Starting from this basic information, new strategies of control, which include breeding for resistance and integrated disease management, can be envisaged.
Possibilities for the Flow of Water and Blood through a Graphene Layer in a Geometry Analogous to Human Arterioles: An Observational Study
Authors: Shankar Narayan S. , Saeed Abdulkafi M. , Fatima Nahid , Al-Duais Fuad S. , Alharbi Khalid Abdulkhaliq M. , Puneeth Venkatesh , Gorji M. R. , Kheder Nidhal Ben , Abdelmohsen Shaimaa A. M. 
Published: February 2023

Atherosclerosis and aneurysm are two non-communicable diseases that affect the human arterial network. The arterioles undergo dimensional changes that prominently influence the flow of oxygen and nutrients to distal organs and organ systems. Several studies have emerged discussing the various possibilities for the circumstances surrounding the existence of these pathologies. In the present work, we analyze the flow of blood across the stenosis and the aneurysmic sac in contrast with the flow of water to explore alterations in the flow characteristics caused by introduction of the graphene layer. We investigate the blood flow past the graphene layer with varying porosity. The study is undertaken to replace usage of a stent along a blocked artery by inserting a thin layer of graphene along the flow channel in the post-pathological section of the geometry. To explain the flow, a 2D mathematical model is constructed, and the validity and exclusivity of the model’s solution are examined. When the artery wall is assumed to be inelastic, the computation of the mathematical system is evaluated using a finite element method (FEM) solver. We define a new parameter called critical porosity Cεp to explore the flow possibilities through the graphene layer. The findings indicate that the flow pattern was adversely affected by the graphene layer that was added to the flow field. The negative impact on the flow could be due to the position of the graphene layer placed. The Cεp values for the flow of blood across healthy arteriole, stenosed arteriole, and aneurysmic arteriole segments were 5.7%, 3.5%, and 3.5% respectively. The critical porosity values were achieved with precision in terms of linear errors 8.1×10−12, 7.7×10−12, and 3.9×10−12, respectively. The consequences of the present study disclose various possible ways to utilize graphene and its compounds in the medical and clinical arena, with a prior exploration of the chemical properties of the compound. The idea and the methodology applied for the present study are novel as there have been no previous research works available in this direction of the research field.
Heterotrophic and Photoautotrophic Media Optimization Using Response Surface Methodology for the Novel Microalga Chlorococcum amblystomatis
Authors: Correia Nádia , Pereira Hugo , Schulze Peter S. C. , Costa Monya M. , Santo Gonçalo E. , Guerra Inês , Trovão Mafalda , Barros Ana , Cardoso Helena , Silva Joana L. , Gouveia Luísa , Varela João 
Published: February 2023

The nutritional requirements of novel microalgal strains are key for their effective cultivation and metabolite content. Therefore, the optimization of heterotrophic and photoautotrophic culture media is crucial for novel Chlorococcum amblystomatis growth. Heterotrophic and photoautotrophic biomass samples were characterized to identify the differences between their heterotrophic and photoautotrophic biomass composition and their biotechnological potential. Media optimization through surface response methodology led to 44.9 and 51.2% increments in C. amblystomatis-specific growth rates under heterotrophic and photoautotrophic growth, respectively. This microalga registered high protein content (61.49–73.45% dry weight), with the highest value being observed in the optimized photoautotrophic growth medium. The lipid fraction mainly constituted polyunsaturated fatty acids, ranging from 44.47 to 51.41% for total fatty acids (TFA) in cells under heterotrophy. However, these contents became significantly higher (70.46–72.82% TFA) in cultures cultivated under photoautotrophy. An interesting carotenoids content was achieved in the cultures grown in optimized photoautotrophic medium: 5.84 mg·g−1 β-carotene, 5.27 mg·g−1 lutein, 3.66 mg·g−1 neoxanthin, and 0.75 mg·g−1 violaxanthin. Therefore, C. amblystomatis demonstrated an interesting growth performance and nutritional profile for food supplements and feed products that might contribute to meeting the world’s nutritional demand.