bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application Deployment Automation by Streamlining CI/CD Pipelines
Authors: Ameta Upasana , Vyas Ruchi 
Published: May 2023

Conceptualize a scenario where the development, actions, quality affirmation, and information surveillance teams collaborate with the product owners to guarantee that the organisation achieves its goals for profitability, security, and cost-cutting. Together, they achieve world-class stability, reliability, availability, and security while conducting multiple number of code deployments each day. This enables the quick progress of planned work into creation. The testing of apps and InfoSec operations only take place at the conclusion of a project when it is too late to make any corrections. Development and IT Operations are adversaries in our environment. If any problems are found, and nearly every important task requires excessive amounts of backbreaking labour and handoffs, keeping us waiting all the while. The work quality, particularly the deployment of product, is challenging and disordered as a result, which has an adverse effect on customers and the business. This not only adds to the extraordinarily long lead times for getting anything done. As a result, there is lack of goals, and the whole company is dissatisfied with developers’ performance, which leads to decrement in budget and frustrated workers feel incapable to modify the scenario and its results. The major objective is to build a platform for developers that can compile, test and run the application with the least specifications and configurations and also conceptualize the piece of deployment with a more relaxed architecture and a small learning period so that developers can take full advantage of multiple platforms available as a cloud service without any inconvenience.
The Effect of Puzzle Educational Game Tools on Fine Motor Development in Pre-school Children at Al-Wahdah Kindergarten Bandung City
Authors: Divta Safira Riska , Lukitasari Depi , Nurlita Lita 
Published: May 2023

Fine motor development is a movement that uses smooth muscles or certain parts of the body that are influenced by learning and practicing opportunities. Delayed fine motor development results in children's development being inappropriate for their age. Overcoming this, need stimulation to improve fine motor skills such as playing a puzzle. The purpose of this study was to determine the effect of Educational Games Tools puzzle on fine motor development in children. This type of research is pre-experimental research with one group pre-test post-test design. The sample of this study was children aged 5-6 years in TK Al-Wahdah totaling 45 samples. The instrument of this research used a modified sheet of KPSP fine motor. Analysis of univariate data before being treated to playing puzzles, found that there were 33 children in the appropriate category (73.3%) and 12 people in the unsuitable category (26.7%). After being given therapy playing puzzle children in the appropriate category were 45 people (100.0%). Based on the results of calculations using the Mc Nemar test, a p-value of 0.000 < (0.05) was obtained, and X counted 14.08 >X table 3.841. It can be concluded that there is an effect of puzzle educational game tools on fine motor development in pre-school age children at TK Al-Wahdah Bandung City. For teachers and health centers it is recommended to be able to redevelop puzzle games by stimulating children to use puzzles that are more varied and harmless, and can pay more attention to fine motor development in children in the future.
Faktor-Faktor yang Mempengaruhi Pengetahuan Keluarga tentang Penanganan Pre-Hospital pada Pasien Stroke
Authors: Muhsinin Siti Zuraida , Rukandani Baiq Melinda Firda 
Published: May 2023

Stroke masih menjadi permasalahan kesehatan prioritas karena merupakan penyebab penyakit ke 2 (dua) di dunia. Manajemen pre-hospital stroke merupakan pelayanan ke pasien pertama kali ditemukan dan selama proses transportasi hingga pasien berada pada pelayanan kesehatan. Penanganan yang cepat dan tepat merupakan salah satu kunci penting dalam mengurangi kematian dan meminimalkan kerusakan otak yang ditimbulkan oleh stroke. Tujuan penelitian ini adalah untuk mengidentifikasi faktor-faktor yang mempengaruhi pengetahuan keluarga tentang penanganan pre-hospital pada pasien stroke di RSUD Kota Mataram. Jenis penelitian ini adalah penelitian deskriptif yang mencoba mendeskripsikan atau menggambarkan faktor-faktor yang mempengaruhi pengetahuan keluarga tentang penanganan pre-hospital pada pasien stroke. Jumlah sampel dalam penelitian ini 33 orang diambil dengan teknik consecutive sampling, instrument yang digunakan untuk pengumpulan data adalah kuesioner. Hasil penelitian ini menujukkan faktor-faktor yang mempengaruhi pengetahuan keluarga tentang penanganan pre-hospital pada pasien stroke di RSUD Kota Mataram : pertama, usia 26-35 sebanyak 12 orang (36.7%). Kedua, pendidikan SMA sebanyak 14 orang (42.4%). Ketiga, Pekerjaan non-kesehatan sebanyak 16 orang (48.5%). Keempat, tidak ada pengalam merawat pasien stroke sebanyak 16 orang (48.5%). Dan terakhir, tidak mendapat informasi terkait dengan penanganan pre-hospital pada pasien stroke sebanyak 15 orang (45.5). Kurangnya pengetahuan keluarga harus menjadi perhatian tim kesehatan, terkait dengan faktor diatas, tim kesehatan harus memberikan intervensi untuk meningkatkan pengetahuan dengan memberikan informasi kepada keluarga atau masyarakat, dengan harapan keluarga dan masyarakat dapat memberikan penanganan yang tepat pada pasien ketika mengalami serangan stroke sebelum mereka dibawa ke rumah sakit.
Reumatoid Factor Examination in Thalassemia Patients
Authors: Setiawan Doni , Hiytulmadani Via Oktaviani , Farihatun Atun 
Published: May 2023

Background & Objective Patients with thalassaemia major with severe anaemia must receive blood transfusions for life. Giving continuous blood transfusions can cause iron accumulation in body tissues so that it can conclude complications, one of which is rheumatoid arthritis due to iron deposition in synovial tissue.
This study is to determine the results of rheumatoid factor examination in thalassaemia patients with blood transfusion therapy.
Method the research used is descriptive. The sampling technique uses incidental with a large number of samples as many as 66.
Result Based on the results of the study obtained positive results as many as 11 (17%) people with an average Rheumatoid Factor level of 29 IU/mL, and negative results as many as 55 (83%) people.
Conclusion Thalassaemia patients with blood transfusion therapy show the risk of rheumatoid arthritis with positive results of rheumatoid factor examination.
Habitabilidad urbana, una categoría para analizar vivienda social en México en el siglo XXI
Authors: Valdez Calva Silvia Andrea , Romero Guzmán Liliana 
Published: May 2023

La reflexión sobre el habitar en la vivienda puede realizarse desde lo social para comprender que ésta trasciende al territorio donde se emplaza. Co­mo lo señala Borja, “la vivienda es uno de los elementos que hacen la ciudad; pero, sin estar integrada a la ciudad, la vivien­da no es adecuada” (2016: 8). Por lo tanto, la vivienda es el elemento de primera instancia que permite a la persona desenvolverse en la ciudad, pero es necesario que se encuentre inserta al tejido urbano para facilitar las condiciones de habitabilidad que brinda la ciudad.
El presente artículo tiene como objetivo reconocer la integración de la habitabilidad en la vivienda social en­tendida como una forma de urbanización que surge de las políticas habitacionales. El método parte de la refle­xión teórica de los conceptos habitabilidad urbana, vi­vienda social y periferia, para comprenderlos como pro­cesos integrales dentro de la ciudad. En los resultados se identifican elemen­tos mínimos —al interior y al exterior— que debe contener la vivienda social emplazada en la periferia con relación a la habitabilidad urbana para satisfacer las ne­cesidades básicas de sus habitantes dentro del contex­to mexicano en el siglo XXI.
O diário de campo como instrumento na pesquisa científica: contribuições e orientações
Authors: Teixeira Érica Jaqueline Pizapio , Pacífico Juracy Machado , Barros Josemir Almeida 
Published: May 2023

O trabalho apresenta reflexões acerca da construção e do uso do diário de campo na pesquisa. Acontece através de uma observação realizada com crianças da educação infantil de uma escola situada na área do campo e de suas brincadeiras no ambiente escolar. O resultado nasce a partir de um projeto de Doutorado em Educação Escolar pela Universidade Federal de Rondônia. Trata como objetivo demonstrar o passo a passo da construção de um diário de campo na pesquisa, orientando o uso do mesmo na coleta de dados, visto na metodologia qualitativa e no bojo das ciências humanas, como uma ferramenta metodológica imprescindível em pesquisas dessa natureza. Com isso, ensina como o pesquisador poderá realizar registros confiáveis ao observar ações e interações das crianças, nesse caso, no ambiente escolar. A conceituação e as estruturas teóricas sobre o diário de campo seguiu orientações de Bogdan e Biklen (1994), bem como, de pesquisadores que se utilizaram desse instrumento de registro na pesquisa, como é o caso do antropólogo Malinowski (1967); Débora Diniz (2017) e Brandão (1982). Ambos demonstram o instrumento de coleta, em diferentes formatos, garantindo as especificidades desse registro na pesquisa. O estudo considera que o diário de campo é um relevante instrumento de registro em pesquisas com crianças e/ou na área das ciências humanas e socais. Reflete que o alcance de resultados significativos e densos em uma investigação, será possível, a partir de uma observação minuciosa, dos cuidados com a reescrita em memorandos, após a volta do campo de pesquisa, e então, opulente material de dados.
Hiperplasia quística prostática en un perro joven: reporte de caso
Authors: Cuesta-Valle Daniel Fernando , Lima-Melo Araceli , Aguilar-Caivinagua Andrés Santiago 
Published: May 2023

Se presenta a consulta un perro macho de 3 años de edad, raza Pastor Alemán en el cual se realizó el plan de exploración clínica, encontrándose masa en hipogastrio y mesogastrio, sin presencia de dolor o molestias a la manipulación, en el estudio ecográfico se pudo observar que dicho hallazgo es la próstata agrandada con un volumen de 249.6 cc, desplazada hacia craneal con grandes quistes, 2.07 cm y 0.86 cm siendo estos los más considerables, además de presentar oclusión de la uretra y nódulos linfáticos reactivos, en la citología prostática se obtiene proliferación epitelial benigna con componente quístico, en el hemograma se presenta trombocitopenia perdida por hematuria, en la bioquímica sérica se observó hiperazotemia posrenal, hiperproteinemia por hiperglobulinemia y disminución de relación A/G por inflamación crónica; en el examen microscópico de la orina se observan células escamosas, piocitos, eritrocitos y bacterias (cocos 2+); el tratamiento administrado fue antibiótico (amoxicilina más ácido clavulánico a dosis de 25 mg/kg cada 8 horas por 7 días), un inhibidor especifico de la 5-a-reductasa de tipo 2 (finasteride 10 mg/kg cada 12 horas por 10 días), AINE (meloxicam 0.2 mg/kg cada 24 horas por 5 días), además de esterilizar al paciente. El control se realizó 5 días post cirugía, obteniendo disminución del volumen prostático en 87.28 cc esto representa el 65% de reducción de tamaño, mediante resonancia magnética a los 138 días post castración se determinó que la próstata redujo el tamaño en un 93.9% y se descartó proceso neoplásico.
SCALING OF VERO CELL CULTURE FOR THE PRODUCTION OF BIOLOGICAL PRODUCTS
Authors: Seidakhmetova B. A. , Zhapparova G. A. , Marakhovskaya L. G. , Terebay A. A. , Nakhanov A. K. 
Published: May 2023

vaccine production is considered the most effective way to prevent and control the spread of infectious diseases. The transplantable Vero cell line is now widely used for vaccine production.The aim of this study was to investigate the optimal parameters for growing Vero cell cultures in cell factories for large-scale vaccine production. For the scaling process, the seed concentration of cells was determined. The results of the studies showed that at a cell inoculum concentration of 2.0x105 cells/ml, a monolayer is formed in 1-2 days and is the most optimal for cultivating most viruses. Multilayer cell culture systems for industrial scales provide a one-stop production solution. The convenient and cost-effective format of cell factories saves space, time and labor and reduces the risk of contamination.In this paper, Vero cell culture is scaled up in cell factories because this cell culture method is necessary to create cost-effective workflows in large volumes. The study showed that the inoculum concentration, the cell proliferation index, and the ratio of the dispersing mixture for cell removal are comparable to routinely used T-vials.
BAĞIMSIZ DENETİMİN GÖZETİMİ BAĞLAMINDA 2020-2021 DÖNEMLERİNE İLİŞKİN KGK YILLIK İNCELEME RAPORLARININ ANALİZİ
Authors: KELEŞ Dursun 
Published: May 2023

KGK, muhasebe ve denetim işlemlerinde ülkeler arasında uygulama birliğinin sağlanması amacıyla gerekli standartları yayımlamak ve güvenilir finansal bilgilerin raporlanmasını teminen gerçekleştirilen bağımsız denetim faaliyetlerinin gözetiminin yapılması amacıyla kurulmuştur. KGK, bağımsız denetimin gözetimi faaliyeti kapsamında gerek bağımsız denetim kuruluşları gerekse bağımsız denetçiler üzerinde inceleme faaliyetlerinde de bulunmaktadır. Bu inceleme faaliyetleri, gerçekleştirilen bağımsız denetim çalışmalarının mevzuat vb. yasal düzenlemelere uygun şekilde gerçekleştirilip gerçekleştirilmediğinin tespit edilmesi amacıyla yapılmaktadır. İnceleme sonuçları ise, KGK tarafından hazırlanan yıllık inceleme raporları aracılığıyla raporlanmaktadır.
Bu çalışmanın amacı, KGK tarafından yerine getirilen bağımsız denetimin gözetimi faaliyetlerine ilişkin yıllık inceleme raporlarının analiz edilmesidir. Bu amaçla, KGK’nın gerek bağımsız denetim kuruluşları gerekse bağımsız denetçilerin yapmış oldukları denetim çalışmalarına yönelik inceleme sonuçlarının yer aldığı 2020 ve 2021 yıllarına ait yıllık inceleme raporları kurumun internet sitesinden temin edilmiştir. Yıllık inceleme raporları üzerinde yapılan analiz sonuçlarına göre; bağımsız denetim siciline kayıtlı ve denetim üstlenen bağımsız denetim kuruluşu ve bağımsız denetçi sayısına rağmen gözetim faaliyetleri kapsamında incelemeye tabi tutulan bağımsız denetim kuruluşu ve bağımsız denetçi sayısının oldukça düşük olduğu görülmüştür. Bununla birlikte, KGK tarafından hazırlanan inceleme raporlarında 2021 yılında tespit edilen eksikliklere ilişkin bulgu sayısının 2020 yılına göre önemli ölçüde artış gösterdiği anlaşılmıştır.
ANALISIS MUTU MARGARIN DENGAN PERBANDINGAN BAHAN BAKU MINYAK GORENG KELAPA : MINYAK GORENG SAWIT
Authors: Rifkowaty Encik Eko Rifkowaty , SP Irianto , Sibuea Budi Pratomo , Sariyanti Devi , Sari Shelvy Antika 
Published: May 2023

Margarin merupakan emulsi (w/o), berbahan dasar minyak nabati. Penelitian ini terdiri dari 3 (tiga) perlakuan perbandingan minyak antara lain; minyak goreng kelapa : minyak goreng sawit 50:50 ; 70:30 ; dan 90:10. Analisis mutu yang dilakukan adalah uji perbandingan pasangan, uji hedonik, kadar air, dan asam lemak bebas. Hasil uji perbandingan pasangan margarin pada atribut warna perlakuan 50:50 sama dengan warna margarin di pasaran, sedangkan atribut aroma dan rasa pada ketiga perlakuan berbeda dengan aroma dan rasa margarin di pasaran. Hasil rerata uji hedonik perlakuan 50:50 memiliki skor tertinggi (paling disukai). Berdasarkan ANOVA pada ketiga perlakuan atribut warna dan aroma berbeda nyata, sedangkan atribut rasa tidak berbeda nyata. Berdasarkan analisis kadar air pada perlakuan 50:50, 70:30, dan 90:10, berturut-turut yaitu 5,30, 6,37 dan 6,95%, sedangkan asam lemak bebas berturut-turut 1,17, 1,47 dan 1,83%. Persentase kadar air memenuhi SNI 01-3541-2002, namun tidak demikian dengan asam lemak bebas
Molecular mechanisms of effects of ionizing radiation action. Irradiation effect on protein (literary review)
Authors: Puzan N. D. , Cheshik I. A. 
Published: May 2023

Target effects (direct and indirect effects of ionizing radiation). When exposed to ionizing radiation, it damages vital intracellular biomolecules which leads to multiple damage to cells and tissues as well as pathophysiological diseases such as inflammation, immunosuppression, etc. Such damage can be caused by direct ionization of biomolecules, but in almost 70% of cases due to indirect radiolysis of intracellular water with the formation of reactive oxygen species and free radicals, which ultimately causes oxidative stress.Non-target effects (abscopal effect, adaptive response, bystander effect, genomic instability). Over the past 25 years, many studies have explored the molecular mechanisms underlying in nontargeted effects (also known as effects not aimed at DNA). It is shown that these effects are the result of a huge dynamic and complex process induced in irradiated cells, transmitted to neighboring cells and, to some extent, to the whole body through activation of the immune system.The irradiation effect on protein. Under the direct action of ionizing radiation on a protein, an electron is knocked out of it, resulting in a defective site devoid of an electron, which migrates along the polypeptide chain due to the transfer of electrons until it reaches a site with increased electron-donor properties. At this point, free radicals arise in the side chains of amino acids. Under the indirect effect of ionizing radiation, the formation of free radicals occurs when protein molecules interact with the products of water radiolysis.
PENGELOLAAN SAMPAH SEBAGAI UPAYA PENINGKATAN KUALITAS LINGKUNGAN PERMUKIMAN DI KAWASAN PESISIR DISTRIK JAYAPURA UTARA - KOTA JAYAPURA
Authors: Muabuay Esterlina V , Sitorus Yannice L  M , Musfira Musfira , Pearlyn Maria P 
Published: May 2023

Produksi sampah di Distrik Jayapura Utara, Kota Jayapura, setiap tahun mengalami peningkatan dan sampah yang dihasilkan ini belum dikelola dengan baik oleh masyarakat, sehingga berimplikasi pada kualitas kawasan permukiman, khususnya di kawasan pesisir Distrik Jayapura Utara. Minimnya persepsi masyarakat dalam pengelolaan sampah, minimnya ketersediaan fasilitas persampahan di lokasi studi, dan jarak TPS yang jauh dari pemukiman, diperkirakan merupakan faktor penyebabnya. Penelitian ini bertujuan mengindentifikasi perspektif masyarakat dalam pengelolaan sampah, ketersediaan fasilitas persampahan di kawasan permukiman dan kemudahan untuk mencapainya, dengan pendekatan penelitian kombinasi kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa strategi pengelolaan sampah, sebagai upaya peningkatan kualitas lingkungan permukiman di kawasan pesisir Distrik Jayapura Utara, Kota Jayapura, dilakukan pada pembenahan persepsi masyarakat terlebih dahulu dan penyediaan fasilitas persampahan yang disesuaikan dengan karakteristik permukiman di kawasan pesisir.
PENGARUH PENINGKATAN AKTIVITAS PEMANFAATAN RUANG TERHADAP KONDISI EKONOMI DAN SOSIAL MASYARAKAT LOKAL DI KAMPUNG HOLTEKAMP DISTRIK MUARA TAMI KOTA JAYAPURA
Authors: Kambu Desfilson , Musfira Musfira , Yanthy Normalia O 
Published: May 2023

Kampung Holtekamp merupakan salah satu kampung di Kota Jayapura yang mengalami peningkatan aktivitas pemanfaatan ruang yang cukup pesat. Hal ini terlihat dari perkembangan aktivitas ekonomi dan sosial masyarakat Kampung Holtekamp. Perubahan pemanfaatan ruang berdampak pada berubahnya kondisi ekonomi dan sosial masyarakat lokal di Kampung Holtekamp. Sebelumnya kawasan ini dikenal sebagai hutan sagu, pohon mangrove, pohon cemara serta pohon kelapa dan sesudah pembangunan ruas jalan Hamadi-Holtekamp, kawasan ini berkembang menjadi kawasan terbangun, yang mendukung peningkatan aktivitas ekonomi dan sosial masyarakat setempat. Setelah ada jalan baru tersebut, warga semakin mudah untuk mengakses barang dan jasa, serta mempermudah wisatawan untuk berkunjung ke Pantai Holtekamp. Hal ini berdampak positif terhadap pendapatan masyarakat lokal. Beberapa anggota masyarakat memperoleh peningkatan pendapatan dari menjual hasil alam, karya kerajinan tangan, dan membuka usaha kecil. Identifikasi pengaruh peningkatan pemanfaatan ruang perlu dilakukan untuk melihat seberapa besar dampak yang terjadi setelah pembukaan kawasan di Distrik Muara Tami ini sehingga dilakukan penelitian dengan tujuan untuk mengidentifikasi seberapa jauh perubahan dan peningkatan aktivitas pemanfaatan ruang di Kampung Holtekamp serta pengaruh peningkatan aktivitas tersebut terhadap kondisi ekonomi dan sosial masyarakat lokal di Kampung Holtekamp. Hasil penelitian menunjukkan bahwa ada penambahan luas lahan kegiatan pariwisata, perbelanjaan, dan permukiman lebih dari 50%, berkurangnya lahan perkebunan sekitar 33% serta lahan peternakan sekitar 18%. Persentase warga setempat yang mengalami peningkatan pendapatan sekitar 49% dan terjadi peningkatan kondisi sarana prasarana yang signifikan setelah peningkatan aktivitas pemanfaatan ruang di Kampung Holtekamp.
Physico-Chemical Characteristics and Stability of Essential Oil from Dried Leaves of Pogostemon heyneanus Benth.
Authors: Nogodula Reynaldo 
Published: May 2023

Essential oils were extracted from air-dried leaves of Pogostemon heyneanus Benth. (Indian patchouli) by steam distillation using a Clavenger tube. Physico-chemical properties of the oil like acid value, ester value, optical rotation, refractive index, saponification value, solubility in 90% ethanol, specific gravity, % alcohol, and % aldehyde was deter-mined. Stability studies of the essential oil included the determination of the effect of light, length of storage and temperature. Based on the set standards, the physico-chemical properties of Pogostemon heyneanus Benth. oil do not fall within the specifications for the oils of patchouli. However, these properties may improve later because the quality of the oil could improve through time. Percent alcohol of the oil samples exposed to both light and dark conditions decreased while their percent aldehyde increased. Thin-layer chromatograms showed that middle spots of polar components were not detected under low temperature after 2 hours and more of exposure. At room temperature, at 800C, 1 IOOC, and 1400C, the same number of spots were observed after 2 hours and beyond but at 1700C and boiling point temperatures, an increased number of spots was observed. TLC results of samples exposed to light and dark conditions, respectively, showed an increased number of spots on the fifth month of storage while the samples became more viscous and their color changed from light yellow to yellow-orange.