bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nickel based catalysts supported on porous support for methane steam reforming: potential and short review
Authors: Seman M H A , Othman N H , Osman N , Jani A M M 
Published: March 2023

Abstract
The world is now demanding other sustainable energy that can help explore new technologies, especially energy conversion and storage. Hydrogen is regarded as one of the most promising oils and gas successors as a fuel due to its high energy content per unit mass and it burns completely free of pollutants. A widely used method for hydrogen production is steam reforming methane (SRM) from biogas. In the SRM process, using a catalyst is crucial, and, if compared to the available metal-based catalysts, Ni-based catalysts provide an acceptable high activity and a lower cost. In addition, the support material of a catalyst significantly affects its stability, especially for catalysts exposed to elevated temperatures. In this work, porous alumina support was used as a support material for the preparation of a nickel-based catalytic hollow membrane reactor. Porous alumina support was fabricated using a double-step anodization method. The presence of large pores (≈120 nm) on support material contributes to decreasing the resistance to mass transfer. The study also highlights the recent progress on methane steam reforming reaction, giving a short overview of catalyst utilization and the fundamentals of SRM through the developed membrane reactor.
Identification of Volcanic Geothermal Systems Based on Integrated Study of Volcanostratigraphy, Structural Geology, and Fluid Geochemistry in Southern Ngada Field, Indonesia
Authors: Pradipta Devito , Suryantini  , Rudyawan Alfend , Kusnadi Dedi , Permana Lano Adhitya 
Published: March 2023

Abstract
Southern Ngada is one of the areas that shows occurrence of volcanic geothermal potential in East Nusa Tenggara. The spreading volcanoes in the study area raised a hypothesis that the Southern Ngada Geothermal Field consists of several geothermal systems. The spreading volcanoes showed the presence of at least three volcanoes and manifestation clusters, which are Nage, Keli-Bena, and Wolo Puti Clusters. This research aimed to identify the number, type, and characteristics of geothermal systems in Southern Ngada Geothermal Field. The identification is conducted through the integration of geomorphology, volcanostratigraphy, structural geology, and geochemistry of fluid manifestation. The determination of geothermal system in Southern Ngada Geothermal Field is important to identify the field characteristics and reduce exploration risks. The Southern Ngada Field constitutes of the pre-caldera, post-caldera, and recent volcanism products. The study area is intensively deformed through strike slip faults and resembled Riedel Shear patterns. Fluid manifestation geochemistry in the study area showed various type of waters, which consists of Cl-SO4, SO4, and SO4-HCO3 waters with meteoric water mixing. The solfatara is associated with active magmatic gases due to boiling of reservoir beneath cinder cones. The fluid mixing processes are explained furthermore in Schoeller diagram plot. The integration of analyses showed the presence of Nage, Keli-Bena, and Wolo Puti Geothermal Systems with each different volcanostratigraphy, structural setting, and fluid mixing processes. The Nage System is associated with inferred heat source beneath the Nage Caldera and eastern part master and antithetic fault. The Keli-Bena System is associated with inferred heat source beneath Bena Crater and western antithetic fault. The Wolo Puti System is associated with inferred heat source beneath cinder cone volcanoes and northern extensional structures.
Water-Rock Interactions in the Metamorphic Complex of Geothermal Field: Case Study in Wahlua Complex, Buru Island
Authors: Gati Rai , Suryantini  , Sibarani Betseba 
Published: March 2023

Abstract
In Indonesia, surface thermal manifestation is commonly found in a volcanic geological setting. However, hot springs and alteration minerals in study area occur on metamorphic rock. In order to study its correlation with the emergence of the thermal fluid, the objective of this study is to characterize each metamorphic zone based on rock chemistry and the appearance of index minerals. Consequently, the correlation with thermal fluid chemistry can be observed. Data for this study are surface rock samples and thermal manifestation data. Metamorphic zones were determined by integrating geomorphology, petrography, and X-Ray Fluorescence (XRF) analyses. Three metamorphic zones were identified, namely, Garnet Zone, Biotite Zone, and Chlorite Zone. Garnet Zone is characterized by high concentrations of CaO and Al2O3 due to the presence of garnet. The abundance of biotite and muscovite in Biotite Zone may contribute to the highest concentration of K2O than the other two zones. Meanwhile, Chlorite Zone is characterized by the concentrations of SiO2, Fe2O3, and MgO. However, the composition of MgO might be influenced by mineral-fluid reaction. There are two clusters of thermal manifestation, which are western and eastern cluster manifestations. Western cluster manifestations are in the Biotite Zone. Meanwhile, the eastern cluster manifestation is in the Chlorite Zone. However, both clusters’ fluid chemistry shows significant differences in some elements such as SiO2, Na, K, Fe, and Mg concentration. It might suggest that the enrichment and depletion of these constituents in thermal fluid might correlate with each metamorphic zone’s characteristics. An inconsistent pattern between thermal fluid composition and rock chemistry was found in Mg concentration. It is most likely that the Mg concentration was influenced by groundwater dilution rather than the mineral-fluid interaction. The study concludes that the appearance of index minerals shows consistencies with composition variation of some elements in the manifestation fluid, such as SiO2, Na, K, and Fe.
Advances of typical mesoporous materials and the application in drug delivery
Authors: He Suna , Pan Haofeng , Zhang Junyang 
Published: March 2023

Abstract
For the excellent drug delivery systems, advanced functional materials are indispensable. In recent years, mesoporous materials have shown a promising prospect and attracted much attention in the field of drug delivery. The research of mesoporous materials as drug carriers becomes to be a hot-spots. As a drug vehicle, it is favored by scientists due to the advantages in increasing drug dissolution and bioavailability, improving drug stability, sustained and controlled drug release, reducing drug side effects, good biocompatibility, targeting and so on. The anticipated in vivo performance for the mesoporous materials based drug delivery systems can be improved through optimizing the synthesis conditions or modifying the materials. In the paper, mesoporous silica nanoparticles (MSNs), mesoporous carbon nanoparticles (MCNs), organic frameworks (OFs), mesoporous hydroxyapatite (mHAp) are selected as the representative mesoporous materials. The structural characteristics, preparation methods, application in the field of drug delivery of above materials are reviewed, and the future research is prospected.
Two-dimensional C6X (X = P2, N2, NP) with ultra-wide bandgap and high carrier mobility
Authors: Chen Xiaowei , Li Renqun , Lin Jiahe , Lin Qiubao , He Hongsheng 
Published: March 2023

Abstract
Two-dimensional (2D) materials with ultra-wide bandgap and high carrier mobility are highly promising for electronic applications. We predicted 2D C3P, C3N and C6NP monolayers through density-functional-theory calculations. The phonon spectra and Ab initio molecular dynamics simulation confirm that the three 2D materials exhibit good phase stability. The C3P monolayer shows excellent mechanical flexibility with a critical strain of 27%. The C3P and C6NP monolayers are ultra-wide bandgap semiconductors based on Heyd-Scuseria-Ernzerhof hybrid functional (HSE06) calculation. The C3P monolayer has a direct bandgap of 4.42 eV, and the C6NP and C3N monolayer have indirect bandgaps of 3.94 and 3.35 eV, respectively. The C3P monolayer exhibits a high hole mobility of 9.06 × 104 cm2V−1s−1, and the C3N monolayer shows a high electron mobility of 4.52 × 104 cm2V−1s−1. Hence, the C3P, C3N, and C6NP monolayers are promising materials for various electronic devices.
Comparison of intra- and inter-patient intensity standardization methods for multi-parametric whole-body MRI
Authors: Ceranka Jakub , Lecouvet Frédéric , Michoux Nicolas , de Mey Johan , Raeymaekers Hubert , Metens Thierry , Vandemeulebroucke Jef 
Published: March 2023

Abstract

Objective. To test and compare different intensity standardization approaches for whole-body multi-parametric MR images, aiming to compensate voxel intensity differences between scans. These differences, common for magnetic resonance imaging, pose problems in image quantification, assessment of changes between a baseline and follow-up scan, and hinder performance of image processing and machine learning algorithms. Approach. In this work, we present a comparison on the accuracy of intensity standardization approaches with increasing complexity, for intra- and inter-patient multi-parametric whole-body MRI. Several approaches were used: z-scoring of the intensities, piecewise linear mapping and deformable mapping of intensity distributions into established reference intensity space. For each method, the impact on standardization algorithm on the use of single image or average population distribution reference; as well as, whole image and region of interest were additionally investigated. All methods were validated on a data set of 18 whole-body anatomical and diffusion-weighted MR scans consisting of baseline and follow-up examinations acquired from advanced prostate cancer patients and healthy volunteers. Main results. The piecewise linear intensity standardisation approach provided the best compromise between standardization accuracy and method stability, with average deviations in intensity profile of 0.011-0.027 and mean absolute difference of 0.29-0.37 standard score (intra-patient) and 0.014-0.056 (inter-patient), depending on the type of used MR modality. Significance. Linear piecewise approaches showed the overall best performance across multiple validation metrics, mostly because of its robustness. The inter-patient standardization proved to perform better when using population average reference image; in contrary to intra-patient approach, where the best results were achieved by standardizing towards a reference image taken as the baseline scan.
Omicron BA.4/5 Neutralization and T-Cell Responses in Organ Transplant Recipients After Booster Messenger RNA Vaccine: A Multicenter Cohort Study
Authors: Ferreira Victor H , Ierullo Matthew , Mavandadnejad Faranak , Kurtesi Alexandra , Hu Queenie , Hardy W Rod , Hall Victoria G , Pinzon Natalia , Yotis Demitra , Gingras Anne-Claude , Belga Sara , Shalhoub Sarah , Hébert Marie-Josée , Humar Atul , Kabbani Dima , Kumar Deepali 
Published: March 2023

Abstract

Background
In solid organ transplant (SOT) recipients, the primary vaccination series against Coronavirus Disease 2019 is 3 doses followed by boosters. We determined whether a fourth dose booster induced Omicron BA.4/5 neutralizing antibodies (nAbs) and T cells in a large multicenter cohort study.

Methods
Serum was collected 4–6 weeks post-third and post-fourth doses of messenger RNA vaccine in 222 SOT recipients. nAbs were measured using a pseudovirus neutralization assay that targeted the Omicron BA.4/5 spike protein. A subset underwent T-cell testing.

Results
The median age of the cohort was 63 years (interquartile range [IQR], 50–68) with 61.7% men. BA.4/5 nAb detection increased from 26.6% (59 of 222) post-third dose to 53.6% (119 of 222) post-fourth dose (P &lt; .0001). In patients with breakthrough infection prior to the fourth dose (n = 27), nAbs were detected in 77.8% and median nAb titers were significantly higher compared with those with 4 vaccine doses alone (P &lt; .0001). Factors associated with a low BA.4/5 neutralization response after the fourth dose were older age (odds ratio [OR], 0.96; 95% confidence interval [CI], .94–.99), mycophenolate use (OR, 0.39; 95% CI, .20–.77) and prednisone use (OR, 0.34; 95% CI, .18–.63), and vaccine type (OR, 0.72; 95% CI, .51–.99), while breakthrough infection prior to the fourth dose (OR, 3.6; 95% CI, 1.3–9.9) was associated with a greater nAb response. Polyfunctional BA.4/5-specific CD4+ T cells significantly increased after 4 doses and were identified in 76.9% of patients at a median frequency of 213/106 cells (IQR, 98–650).

Conclusions
In summary, a booster significantly increases BA.4/5-specific neutralization and polyfunctional CD4+ T-cell responses, suggesting protection from severe disease even with new Omicron variants. However, SOT recipients who are older and on mycophenolate and prednisone need additional preventative strategies.
New Integral Distinguishers On Permutation Of Whirlpool
Authors: Wang Bolin , Wu Wenling , Zhang Yuhan , Zhang Li 
Published: March 2023

Abstract
Whirlpool is a hash function that has been standardized by ISO/IEC. In this paper, we develop a new type of distinguishing property for its underlying permutation $ W $. Division property proposed by Todo at EUROCRYPT 2015 was initially used in the integral cryptanalysis of symmetric-key algorithms. This work for the first time utilizes the MILP method to search for the integral distinguishers of $ W $ in both the forward and backward directions while concentrating on word-based division property. Under the known-key model, the fact that the permutation used in the hash function does not depend on any secret parameters allows the previous properties to be exploited from the middle, i.e. from an intermediate internal state. Therefore, we apply the inside-out strategy which is the essential step in the zero-sum property to connect the trails in opposite directions. Consequently, we obtain new distinguishers up to full rounds for the $ W $. To further reduce the complexity of the integral distinguishers, we add one round in the middle with the help of subspace trails. Finally, we succeed in extending the length and improving the complexity of the integral distinguishers. To the best of our knowledge, all the results in this paper are competitive with the previous work in both computational cost and memory complexity. It is worth mentioning that the methods presented in this paper are applicable to a broad class of hash functions.
Common congenital heart problems in acute and intensive care
Authors: Buber Jonathan , Valle Christopher , Valente Anne Marie 
Published: March 2023

AbstractOver the past five decades, there have been multiple advances in the treatment of congenital heart defects, resulting in an increasing population of adults living with congenital heart disease (CHD). Despite improved survival, CHD patients often have residual haemodynamic sequelae and limited physiologic reserve and are at increased risk for acute decompensation with occurrence of arrhythmias, heart failure, and other medical conditions. Comorbidities occur more frequently and at an earlier age in CHD patients than in the general population. The management of the critically ill CHD patient requires an understanding of the unique aspects of congenital cardiac physiology as well as the recognition of other organ systems that may be involved. Certain patients may be candidates for mechanical circulatory support, and goals of care should be established with advanced care planning.
Annotated genome sequence of a fast-growing diploid clone of red alder (Alnus rubra Bong.)
Authors: Hixson Kim K , Fajardo Diego A , Devitt Nicholas P , Sena Johnny A , Costa Michael A , Meng Qingyan , Boschiero Clarissa , Zhao Patrick Xuechun , Baack Eric J , Paurus Vanessa L , Davin Laurence B , Lewis Norman G , Bell Callum J 
Published: March 2023

Abstract
Red alder (Alnus rubra Bong.) is an ecologically significant and important fast-growing commercial tree species native to western coastal and riparian regions of North America, having highly desirable wood, pigment, and medicinal properties. We have sequenced the genome of a rapidly growing clone. The assembly is nearly complete, containing the full complement of expected genes. This supports our objectives of identifying and studying genes and pathways involved in nitrogen-fixing symbiosis and those related to secondary metabolites that underlie red alder's many interesting defense, pigmentation, and wood quality traits. We established that this clone is most likely diploid and identified a set of SNPs that will have utility in future breeding and selection endeavors, as well as in ongoing population studies. We have added a well-characterized genome to others from the order Fagales. In particular, it improves significantly upon the only other published alder genome sequence, that of Alnus glutinosa. Our work initiated a detailed comparative analysis of members of the order Fagales and established some similarities with previous reports in this clade, suggesting a biased retention of certain gene functions in the vestiges of an ancient genome duplication when compared with more recent tandem duplications.
Numerical modeling of caldera formation using Smoothed Particle Hydrodynamics (SPH)
Authors: Mullet B , Segall P , Fávero Neto A H 
Published: March 2023

SUMMARYCalderas are kilometer-scale basins formed when magma is rapidly removed from shallow magma storage zones. Despite extensive previous research, many questions remain about how host rock material properties influence the development of caldera structures. We employ a mesh-free, continuum numerical method, Smoothed Particle Hydrodynamics (SPH) to study caldera formation, with a focus on the role of host rock material properties. SPH provides several advantages over previous numerical approaches (finite element or discrete element methods), naturally accommodating strain localization and large deformations while employing well-known constitutive models. A continuum elastoplastic constitutive model with a simple Drucker–Prager yield condition can explain many observations from analogue sandbox models of caldera development. For this loading configuration, shear band orientation is primarily controlled by the angle of dilation. Evolving shear band orientation, as commonly observed in analogue experiments, requires a constitutive model where frictional strength and dilatancy decrease with strain, approaching a state of zero volumetric strain rate. This constitutive model also explains recorded loads on the down-going trapdoor in analogue experiments. Our results, combined with theoretical scaling arguments, raise questions about the use of analogue models to study caldera formation. Finally, we apply the model to the 2018 caldera collapse at Kīlauea volcano and conclude that the host rock at Kīlauea must exhibit relatively low dilatancy to explain the inferred near-vertical ring faults.
Theta oscillations in anterior cingulate cortex and orbitofrontal cortex differentially modulate accuracy and speed in flexible reward learning
Authors: Ye Tony , Romero-Sosa Juan Luis , Rickard Anne , Aguirre Claudia G , Wikenheiser Andrew M , Blair Hugh T , Izquierdo Alicia 
Published: March 2023

ABSTRACTFlexible reward learning relies on frontal cortex, with substantial evidence indicating that anterior cingulate cortex (ACC) and orbitofrontal cortex (OFC) subregions play important roles. Recent studies in both rat and macaque suggest theta oscillations (5–10 Hz) may be a spectral signature that coordinates this learning. However, network-level interactions between ACC and OFC in flexible learning remain unclear. We investigated the learning of stimulus–reward associations using a combination of simultaneous in vivo electrophysiology in dorsal ACC and ventral OFC, partnered with bilateral inhibitory DREADDs in ACC. In freely behaving male and female rats and using a within-subject design, we examined accuracy and speed of response across distinct and precisely defined trial epochs during initial visual discrimination learning and subsequent reversal of stimulus–reward contingencies. Following ACC inhibition, there was a propensity for random responding in early reversal learning, with correct vs. incorrect trials distinguished only from OFC, not ACC, theta power differences in the reversal phase. ACC inhibition also hastened incorrect choices during reversal. This same pattern of change in accuracy and speed was not observed in viral control animals. Thus, characteristics of impaired reversal learning following ACC inhibition are poor deliberation and weak theta signaling of accuracy in this region. The present results also point to OFC theta oscillations as a prominent feature of reversal learning, unperturbed by ACC inhibition.
Cementing CO2 into C-S-H: A step toward concrete carbon neutrality
Authors: Stefaniuk Damian , Hajduczek Marcin , Weaver James C , Ulm Franz J , Masic Admir 
Published: March 2023

Abstract
Addressing the existing gap between currently available mitigation strategies for greenhouse gas emissions associated with ordinary Portland cement production and the 2050 carbon neutrality goal represents a significant challenge. In order to bridge this gap, one potential option is the direct gaseous sequestration and storage of anthropogenic CO2 in concrete through forced carbonate mineralization in both the cementing minerals and their aggregates. To better clarify the potential strategic benefits of these processes, here, we apply an integrated correlative time- and space-resolved Raman microscopy and indentation approach to investigate the underlying mechanisms and chemomechanics of cement carbonation over time scales ranging from the first few hours to several days using bicarbonate-substituted alite as a model system. In these reactions, the carbonation of transient disordered calcium hydroxide particles at the hydration site leads to the formation of a series of calcium carbonate polymorphs including disordered calcium carbonate, ikaite, vaterite, and calcite, which serve as nucleation sites for the formation of a calcium carbonate/calcium-silicate-hydrate (C-S-H) composite, and the subsequent acceleration of the curing process. The results from these studies reveal that in contrast to late-stage cement carbonation processes, these early stage (precure) out-of-equilibrium carbonation reactions do not compromise the material's structural integrity, while allowing significant quantities of CO2 (up to 15 w%) to be incorporated into the cementing matrix. The out-of-equilibrium carbonation of hydrating clinker thus provides an avenue for reducing the environmental footprint of cementitious materials via the uptake and long-term storage of anthropogenic CO2.
Mpox (monkeypox)
Authors: Jarrell Lynda , Perryman Kashiris 
Published: March 2023

Abstract:
Mpox (formerly “monkeypox”) is a viral zoonosis that presents similarly to smallpox but is less contagious and causes less severe disease. Mpox may be transmitted from infected animals to humans through direct contact or a scratch or bite. Human-to-human transmission occurs through direct contact, respiratory droplets, and fomites. Two vaccines, JYNNEOS® and ACAM2000®, are currently available for postexposure prophylaxis as well as for prevention in certain populations at high risk for mpox. Most cases of mpox are self-limited; however, tecovirimat, brincidofovir, and cidofovir are available as treatments for at-risk populations.