bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors for Postpartum Depression and Severe Distress among Mothers of Very Preterm Infants at NICU Discharge
Authors: Hofheimer Julie A. , McGowan Elisabeth C. , Smith Lynne M. , Meltzer-Brody Samantha , Carter Brian S. , Dansereau Lynne M. , Pastyrnak Steven , Helderman Jennifer B. , Neal Charles R. , DellaGrotta Sheri A. , O'Shea Thomas Michael D. , Lester Barry M. 
Published: April 2023

Objective To identify psychological, medical, and socioenvironmental risk factors for maternal postpartum depression (PPD) and severe psychological distress (SPD) at intensive care nursery discharge among mothers of very preterm infants.
Study Design We studied 562 self-identified mothers of 641 infants born <30 weeks who were enrolled in the Neonatal Neurobehavior and Outcomes in Very Preterm Infants Study (NOVI) conducted in nine university-affiliated intensive care nurseries. Enrollment interviews collected socioenvironmental data, depression, and anxiety diagnoses prior to and during the study pregnancy. Standardized medical record reviews ascertained prenatal substance use, maternal and neonatal medical complications. The Edinburgh Postnatal Depression Scale and Brief Symptom Inventory were administered at nursery discharge to screen for PPD and SPD symptoms, respectively.
Results Unadjusted analyses indicated mothers with positive screens for depression (n = 76, 13.5%) or severe distress (n = 102, 18.1%) had more prevalent prepregnancy/prenatal depression/anxiety, and their infants were born at younger gestational ages, with more prevalent bronchopulmonary dysplasia, and discharge after 40 weeks postmenstrual age. In multivariable analyses, prior depression or anxiety was associated with positive screens for PPD (risk ratio [RR]: 1.6, 95% confidence interval [CI]: 1.1–2.2) and severe distress (RR: 1.6, 95% CI: 1.1–2.2). Mothers of male infants had more prevalent depression risk (RR: 1.7, 95% CI: 1.1–2.4), and prenatal marijuana use was associated with severe distress risk (RR: 1.9, 95% CI: 1.1–2.9). Socioenvironmental and obstetric adversities were not significant after accounting for prior depression/anxiety, marijuana use, and infant medical complications.
Conclusion Among mothers of very preterm newborns, these multicenter findings extend others' previous work by identifying additional indicators of risk for PPD and SPD associated with a history of depression, anxiety, prenatal marijuana use, and severe neonatal illness. Findings could inform designs for continuous screening and targeted interventions for PPD and distress risk indicators from the preconception period onward.
Key Points
Effect of Statins on the Inflammatory Markers in Patients with Coronary Artery Disease
Authors: Premnath Sujatha Mahadevarao , Nanda Sunil Kumar , Ray Lopamudra , Arokiaraj Mark Chirstopher 
Published: April 2023

Abstract
Introduction Atherosclerosis mediated by inflammatory markers is the corner stone in the pathology of coronary artery disease (CAD). Hyperlipidemia, one of the risk factors is treated with statins. Statins also have a pleotropic role in reducing inflammation. Effect of statins on two inflammatory markers pentraxin 3(PTX 3) and high sensitivity C-reactive protein (hs-CRP) is explored in this study.
Objective This article estimates the levels of serum PTX 3 and hs-CRP in CAD patients with and without statin therapy and correlates the levels with low-density lipoprotein cholesterol (LDL-c) and high-density lipoprotein cholesterol (HDL-c) in CAD patients without statin therapy.
Material and Methods This was a cross-sectional study conducted on 62 patients with CAD diagnosed by coronary angiogram. They were divided into two groups. Group I were the CAD patients on statin therapy and group II were CAD patients who never had any lipid lowering drugs irrespective of their lipid values. Serum PTX3, hs-CRP, and lipid profile were estimated in these groups. Comparison between the groups was done using Student's t-test and correlation analyzed using Pearson's correlation.
Results Serum PTX 3 and hs-CRP levels were higher than the reference range in both the groups. But group I showed significantly low PTX 3 levels (p-value = 0.032) compared with group II. There was a significant positive relationship between PTX 3 and LDL-c (p = 0.003) in group II.
Conclusion CAD patients on statin therapy have lower vessel wall inflammation compared with patients without statin therapy.
Association of Maternal Medical Comorbidities with Duration of Expectant Management in Patients with Severe Preeclampsia
Authors: Cozzi Gabriella D. , Battarbee Ashley N. , Sanjanwala Aalok R. , Casey Brian M. , Subramaniam Akila 
Published: April 2023

Objective This study aimed to estimate the association between number of maternal comorbidities and duration of expectant management and perinatal outcomes in patients with preeclampsia with severe features.
Study Design Retrospective cohort of patients with preeclampsia with severe features delivering live, nonanomalous singletons at 23 to 342/7 weeks' gestation at a single center from 2016 to 2018. Patients delivered for an indication other than severe preeclampsia were excluded. Patients were categorized based on the number (0, 1, or ≥2) of comorbidities present: chronic hypertension, pregestational diabetes, chronic kidney disease, and systemic lupus erythematosus. The primary outcome was proportion of potential expectant management time achieved, that is, days of expectant management achieved divided by total potential expectant management time (days from severe preeclampsia diagnosis to 340/7 weeks). Secondary outcomes included delivery gestational age, days of expectant management, and perinatal outcomes. Outcomes were compared in bivariable and multivariable analyses.
Results Of 337 patients included, 167 (50%) had 0, 151 (45%) had 1, and 19 (5%) had ≥2 comorbidities. Groups differed with respect to age, body mass index, race/ethnicity, insurance, and parity. The median proportion of potential expectant management achieved in this cohort was 1.8% (interquartile range: 0–15.4), and did not differ by number of comorbidities (adjusted β: 5.3 [95% confidence interval [CI]: −2.1 to 12.9] for 1 comorbidity vs. 0 and adjusted β: −2.9 [95% CI: −18.0 to 12.2] for ≥2 comorbidities vs. 0). There was no difference in delivery gestational age or duration of expectant management in days. Patients with ≥2 (vs. 0) comorbidities had higher odds of composite maternal morbidity (adjusted odds ratio: 3.0 [95% CI: 1.1–8.2]). There was no association between number of comorbidities and composite neonatal morbidity.
Conclusion Among patients with preeclampsia with severe features, the number of comorbidities was not associated with duration of expectant management; however, patients with ≥2 comorbidities had higher odds of adverse maternal outcomes.
Key Points
Plasma Kallikrein as a Forgotten Clotting Factor
Authors: Kearney Katherine J. , Spronk Henri M.H. , Emsley Jonas , Key Nigel S. , Philippou Helen 
Published: April 2023

AbstractFor decades, it was considered that plasma kallikrein's (PKa) sole function within the coagulation cascade is the activation of factor (F)XII. Until recently, the two key known activators of FIX within the coagulation cascade were activated FXI(a) and the tissue factor–FVII(a) complex. Simultaneously, and using independent experimental approaches, three groups identified a new branch of the coagulation cascade, whereby PKa can directly activate FIX. These key studies identified that (1) FIX or FIXa can bind with high affinity to either prekallikrein (PK) or PKa; (2) in human plasma, PKa can dose dependently trigger thrombin generation and clot formation independent of FXI; (3) in FXI knockout murine models treated with intrinsic pathway agonists, PKa activity results in increased formation of FIXa:AT complexes, indicating direct activation of FIX by PKa in vivo. These findings suggest that there is both a canonical (FXIa-dependent) and non-canonical (PKa-dependent) pathway of FIX activation. These three recent studies are described within this review, alongside historical data that hinted at the existence of this novel role of PKa as a coagulation clotting factor. The implications of direct PKa cleavage of FIX remain to be determined physiologically, pathophysiologically, and in the context of next-generation anticoagulants in development.
Predictors of Remission of Acromegaly following Surgical Treatment in Growth Hormone-Secreting Pituitary Adenoma
Authors: Konar Subhas , Yeole Ujwal , Shukla Dhaval , Bhat Dhananjaya I. , Sadashiva Nishanth , Devi Bhagavatula Indira 
Published: April 2023

Abstract
Background and Objective Surgery is the treatment of choice for growth hormone (GH)-secreting pituitary adenoma. The remission of random GH depends on various factors. We aimed to evaluate the predictors related to remission of random GH following surgical treatment.
Methods We collected the data retrospectively from the chart review from a single unit of neurosurgery. The diagnostic criteria for remission were a random GH < 1 ng/mL or nadir GH < 0.4 ng/mL after an oral glucose tolerance test.
Results Data from a total of 110 (females 62 [56.4%]) patients were available for follow-up and were analyzed. The mean age was 36.5 years (14–69 years). Vision impairments were seen in 39 (35.5%) patients. The mean duration of symptoms before surgery was 34 months. The mean volume of the tumor was 7.2 mL (0.44–109.8 mL). Knosp grade 3 and 4 tumors were seen in 41.5% of cases. The mean preoperative random GH level was 68.9 ng/mL. Transsphenoidal surgery was done in 107 (97.3%) cases. The gross total resection could be done in 36 (32.7%) cases. At 3 months, 25 (26%) patients had a biochemical remission. In univariable analysis, lower Knosp grade, preoperative GH level < 40 ng/mL, gross total resection, and male gender were associated with remission at 3 months. In regression analysis, preoperative GH and male gender were related to remission at 3 months.
Conclusion The preoperative GH level < 40 ng/mL is associated with higher chances of remission after surgery for GH-secreting pituitary adenoma.
DNA hydrogels for bone regeneration
Authors: Athanasiadou Dimitra , Meshry Nadeen , Monteiro Naara G. , Ervolino-Silva Ana C. , Chan Ryan Lee , McCulloch Christopher A. , Okamoto Roberta , Carneiro Karina M. M. 
Published: April 2023

DNA-based biomaterials have been proposed for tissue engineering approaches due to their predictable assembly into complex morphologies and ease of functionalization. For bone tissue regeneration, the ability to bind Ca
2+
and promote hydroxyapatite (HAP) growth along the DNA backbone combined with their degradation and release of extracellular phosphate, a known promoter of osteogenic differentiation, make DNA-based biomaterials unlike other currently used materials. However, their use as biodegradable scaffolds for bone repair remains scarce. Here, we describe the design and synthesis of DNA hydrogels, gels composed of DNA that swell in water, their interactions in vitro with the osteogenic cell lines MC3T3-E1 and mouse calvarial osteoblast, and their promotion of new bone formation in rat calvarial wounds. We found that DNA hydrogels can be readily synthesized at room temperature, and they promote HAP growth in vitro, as characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, atomic force microscopy, and transmission electron microscopy. Osteogenic cells remain viable when seeded on DNA hydrogels in vitro, as characterized by fluorescence microscopy. In vivo, DNA hydrogels promote the formation of new bone in rat calvarial critical size defects, as characterized by micro-computed tomography and histology. This study uses DNA hydrogels as a potential therapeutic biomaterial for regenerating lost bone.
A contrastive study of Chinese and American online complaints
Authors: Wei Ming 
Published: April 2023

Abstract
Speech acts in CMC (Computer Mediated Communication) have been receiving increasing attention in recent years.
This study attempted to make a cross-cultural comparison of Chinese and American online complaints of restaurants from the
perspective of speech act structure in relation to face management. In spite of likeness in the general taxonomy of retrospective
and prospective speech acts between the two corpora, addressivity appeared to be a strong factor affecting how face was managed
in the specific construction of complaints as speech act sets in the Chinese data set, while such a discrepancy was absent from
the American reviews where the face of restaurants and fellow consumers was not handled with much distinction and discretion.
These findings in terms of the level of sensitivity and adaptation to the context seem to imply that the generally-recognized
distinction of high-context vs. low-context between the two cultures is also manifested in online reviews.
An epistemic interpretation of responses to advice resistance on Chinese phone-ins of family problem
counseling
Authors: Peng Zhuo 
Published: April 2023

Abstract
At present, Epistemics is a popular theory in Western conversation analysis, but few scholars investigate the
responses to the advice resistance on phone-ins from the perspective of Epistemics. This paper explores the responses to the
advice resistance on Chinese phone-ins of family problem counseling from the perspective of Epistemics. It is found that when
responding to the caller’s advice resistance, the host often implements two conversation practices, such as maintaining his/her
original higher epistemic status or constructing higher epistemic status in another epistemic domain. These practices are
consistent with the possibility of the host’s knowledge orientation to strong self-confidence in his/her own professional
knowledge but the lack of confidence in the caller’s relevant knowledge. This study can provide enlightenment for the smooth
development of advice interaction on phone-ins of family problem counseling and expand the application scope of Epistemics.
Enhanced the Bi-(Tri-)partite entanglement between three magnons in a cavity magnomechanics system
Authors: Hidki Abdelkader , Ren Ya-long , Lakhfif Abderrahim , El Qars Jamal , Nassik Mostafa 
Published: April 2023

Abstract
We propose a scheme to generate steady-state bipartite and tripartite entanglement in the cavity magnomechanical system, which consists of a microwave (MW) cavity field, three magnons, and a phonon mode. The three magnons are coupled to the MW cavity via the magnetic dipole interaction, and one of them is also coupled to the phonon mode through the magnetostrictive force. By utilizing the nonlinearity of the magnetostrictive force and the cavity-magnon interaction, the three magnons become mutually entangled, and the steady-state of the system displays a genuine tripartite entanglement. We found that there are optimum parameters, including the detunings and the cavity-magnon coupling, which lead to maximum entanglement. Moreover, the entanglement is robust against thermal effects.
Surface morphology evolution of N-polar GaN on SiC for HEMT heterostructures grown by plasma-assisted molecular beam epitaxy
Authors: Huo Lili , Lingaparthi Ravikiran , Dharmarasu Nethaji , Radhakrishnan K , Chan Casimir 
Published: April 2023

Abstract
The surface morphology evolution of N-polar GaN with growth time was investigated and compared with Ga-polar GaN. N-polar GaN directly grown on SiC substrates was found to have slower 3D-to-2D growth transformation and less coalescence than the Ga-polar counterpart, resulting in rougher surface morphology, whereas the AlN nucleation layer accelerated 3D-to-2D transformation, resulting in smoother surface morphology. N-polar GaN was found to have mound-type surface morphology with clustered atomic steps, unlike the regular screw-type dislocation-mediated step-flow growth observed for Ga-polar GaN. This was explained by the lower diffusion of adatoms on the N-polar surface due to its higher surface energy and higher Ehrlich–Schwoebel barrier. In addition, the increased III/V ratio in N-polar GaN growth was found to reduce the surface roughness from 2.4 nm to 1 nm. Without Si doping, the N-polar GaN high electron mobility transistor (HEMT) heterostructures grown under optimized conditions with smoother surface morphologies exhibited a sheet carrier density of 0.91 × 1013 cm−2 and a mobility of 1220 cm2 (V s)−1. With Si δ-doping, the sheet carrier density was increased to 1.28 × 1013 cm−2 while the mobility was reduced to 1030 cm2 (V s)−1. These results are comparable to the state-of-the-art data of plasma-assisted molecular beam epitaxy-grown N-polar GaN HEMT heterostructures on SiC substrates.
The effect of temperature and excitation energy on Raman scattering in bulk
HfS2
Authors: Antoniazzi Igor , Zawadzka Natalia , Grzeszczyk Magdalena , Woźniak Tomasz , Ibáñez Jordi , Muhammad Zahir , Zhao Weisheng , Molas Maciej R , Babiński Adam 
Published: April 2023

Abstract
Raman scattering (RS) in bulk hafnium disulfide (

HfS

2

) is investigated as a function of temperature (5 K − 350 K) with polarization resolution and excitation of several laser energies. An unexpected temperature dependence of the energies of the main Raman-active (A

1g

and Eg) modes with the temperature-induced blueshift in the low-temperature limit is observed. The low-temperature quenching of a mode ω
1 (134 cm−1) and the emergence of a new mode at approx. 184 cm−1, labeled Z, is reported. The optical anisotropy of the RS in

HfS

2

is also reported, which is highly susceptible to the excitation energy. The apparent quenching of the A

1g

mode at T = 5 K and of the Eg mode at T = 300 K in the RS spectrum excited with 3.06 eV excitation is also observed. We discuss the results in the context of possible resonant character of light-phonon interactions. Analyzed is also a possible effect of the iodine molecules intercalated in the van der Waals gaps between neighboring

HfS

2

layers, which inevitably result from the growth procedure.
Temperature-insensitive high sensitivity refractive index sensor based on tapered no core fiber
Authors: Lu Zhiqi , Liu Changning , Ren Jie , Chen Li , Li Chi , Zhou Wenbiao 
Published: April 2023

Abstract
This study fabricated an ultra-high refractive index (RI) sensor based on tapered no-core fiber (NCF) involving a simple inexpensive process. A splice section of NCF in the middle of single mode fiber was tapered to small diameters. The sensor was sensitive to the surrounding RI with a large measurement range of 1.3330–1.4437. The RI sensitivity differed with varying wavelengths, with a value of 41 916 nm/RIU at approximately 1550 nm, for the RI ranges of 1.4407–1.4437. It yielded a low temperature sensitivity of 8 pm °C−1, which indicates an ultra-low temperature cross-sensitivity. The proposed fiber optic RI sensor can be used in many fields such as medicine and biochemical applications.
On the distinct differences in autonomic regulation between pregnant and non-pregnant women - a heart rate variability analysis
Authors: Bester M , Joshi R , Mischi M , van Laar JOEH , Vullings R 
Published: April 2023

Abstract

Objective. Appropriate adaptation of the maternal autonomic nervous system to progressing gestation is essential to a healthy pregnancy. This is partly evidenced by the association between pregnancy complications and autonomic dysfunction. Therefore, assessing maternal heart rate variability (HRV)—a proxy measure for autonomic activity—may offer insights into maternal health, potentially enabling the early detection of complications. However, identifying abnormal maternal HRV requires a thorough understanding of normal maternal HRV. While HRV in women of childbearing age has been extensively investigated, less is known concerning HRV during pregnancy. Subsequently, we investigate the differences in HRV between healthy pregnant women and their non-pregnant counterparts. Approach. We use a comprehensive suite of HRV features (assessing sympathetic and parasympathetic activity, heart rate (HR) complexity, HR fragmentation, and autonomic responsiveness) to quantify HRV in large groups of healthy pregnant (n = 258) and non-pregnant women (n = 252). We compare the statistical significance and effect size of the potential differences between the groups. Main results. We find significantly increased sympathetic and decreased parasympathetic activity during healthy pregnancy, along with significantly attenuated autonomic responsiveness, which we hypothesize serves as a protective mechanism against sympathetic overactivity. HRV differences between these groups typically had a large effect size (Cohen’s d > 0.8), with the largest effect accompanying the significantly reduced HR complexity and altered sympathovagal balance observed in pregnancy (Cohen’s d > 1.2). Significance. Healthy pregnant women are autonomically distinct from their non-pregnant counterparts. Subsequently, assumptions based on HRV research in non-pregnant women cannot be readily translated to pregnant women.
Configurational dynamics of flexible filaments in bacterial active baths
Authors: Zhang Chunhe , Xie Chenliang , Feng Wei , Luo Hao , Liu Yanan , Jing Guangyin 
Published: April 2023

Abstract
Biopolymers with microscale length and nanoscale cross-sections subjected to active forces is a common non-equilibrium phenomenon in living creatures. It is therefore crucial to intuitively present and investigate the detailed dynamics of such flexible filaments in an active bath full of living matter. Hence, by introducing fluorescent actin filament into an active suspension of motile bacteria at different number densities in a quasi-two-dimensional chamber, we directly visualize the detailed interaction processes and find that bacteria deform a fluctuating filament by relative motion perpendicular to its principal axis of the filament and straighten a filament by parallel motions. We analyzed the evolution of bending energy in dilute and dense bacterial baths with gradual compact or coiled shapes. We successfully introduce a dimensionless number

μ
˜

, named as active elasto-viscous number, which governs the generic deformation of filaments in the bacterial baths by comparing the viscous force generated in the bacterial active baths to the elastic restoring force of filaments. The persistence length measuring the tangential correlation of the flexible filament is found to be proportional to

μ
˜

. Finally, an effective temperature of the bacterial bath is given through the relation between constant stiffness and loading forces instead of the popularly used Einstein relation. Our findings provide detailed information and specific scaling of flexible filaments interplay with active forces and in response to living and crowded environments.
Superfluid dark matter around black holes
Authors: De Luca Valerio , Khoury Justin 
Published: April 2023

Abstract
Superfluid dark matter, consisting of self-interacting light particles that thermalize and condense to form a superfluid in galaxies, provides a novel theory that matches the success of the standard ΛCDM model on cosmological scales while simultaneously offering a rich phenomenology on galactic scales. Within galaxies, the dark matter density profile consists of a nearly homogeneous superfluid core surrounded by an isothermal envelope. In this work we compute the density profile of superfluid dark matter around supermassive black holes at the center of galaxies. We show that, depending on the fluid equation of state, the dark matter profile presents distinct power-law behaviors, which can be used to distinguish it from the standard results for collisionless dark matter.