bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Incidence Rate of Non-Hodgkin’s Lymphoma in Saudi Arabia: An Observational Descriptive Population Based Epidemiological Study from the Saudi Cancer Registry (2006–2016)
Authors: Qattan Malak Yahia 
Published: May 2023

Introduction: Non-Hodgkin’s lymphoma (NHL) consists of several hematologic malignancies arising from B, T lymphocytes or natural killer lymphocytes, and nearly 85–90% originates from B lymphocytes. This current study illustrates frequency of diagnosed NHL cases, age-standardized incidence rate (ASIR) and crude incidence rate (CIR) by age group, year of diagnosis and administrative regions for identifying the distribution, pattern and real condition of NHL in Saudi Arabia.
Methodology: In this study, an epidemiological analysis of NHL cases is conducted on registered cases between 2006 and 2016 from Saudi cancer registry (SCR). For statistical analysis, t-test, sex ratio, Kruskal–Wallis and descriptive statistics were performed by SPSS version 20.0.
Results: A total of 8019 NHL cases were documented from reported from January 2006 to December 2016. Among males, Riyadh region had the highest overall ASIR at 7.9 followed by Eastern region at 6.9 per 100,000 males and lowest overall ASIRs were observed in Jazan and Hail region at 3.5, and the Northern region at 3.9 per 100,000 males. The highest overall ASIR among females was reported in the Riyadh region at 6.9 and Eastern region at 5.2 per 100,000 females and lowest overall ASIR was documented in the Jazan region at 2.2, followed by Hail at 2.4. The overall age-standardized incidence sex ratio of NHL was found to be 1.3 per100,000 in Saudi Arabia.
Conclusion: This study concluded an increase in crude incidence rates and age-standardized incidence rates NHL among Saudi population. Highest overall ASIRs for NHL among males and females from 2006 to 2016 were documented in Riyadh and Eastern region. While, lowest overall ASIRs among males and females were documented in the Jazan and Hail region.
Réponses culturelles à la première vague de la pandémie de COVID-19 dans différentes parties du monde
Authors: Noël Camille , Maiti Tanay , Pereira-Sanchez Victor , Satake Yuto , Orsolini Laura , Durán Avendaño Xenia Margarita , Larnaout Amine , Moussalli Youssef , Soron Tanjir Rashid , Kemunto Silvia , Van Ypersele David , Melapi Tando Abner Sivile , Vadivel Ramyadarshni 
Published: May 2023

L’article rend compte de différents modes d’appréhensions culturelles de la toute première vague de pandémie COVID-19 et des mécanismes d’adaptation subséquents en Inde, au Bangladesh, au Japon, en Syrie, en Nouvelle-Zélande, en Afrique du Sud, au Kenya, en Tunisie, au Salvador, aux États-Unis, en Italie et en Belgique. La culture influence la façon dont une épidémie touche la société, selon l’interprétation de son origine, son mode de propagation et de traitement, ainsi que les réponses à la détresse et les pratiques de santé. Les réponses culturelles à la pandémie contribuent à en contrôler ou accélérer la propagation, voire à unir ou diviser certains secteurs de la société. La culture influence aussi la perception des interventions médicales et donc la présence ou l’absence de demandes d’aide aux services de santé. Les réponses culturelles variées soulignent l’importance de la culture en santé publique, en particulier en cas de crise, dans le choix des mesures sanitaires. Enfin, au creux de la première vague pandémique, l’expérience de rassembler des témoignages d’acteurs de cultures différentes a permis de tisser un lien au sein d’une « jeune » génération de psychiatres vivant dans différentes parties du globe, et les a aidés à faire face au potentiel traumatique du risque d’isolement et de repli, face aux défis de leurs contextes professionnels respectifs.
Droits des femmes, bioéthique et procréation médicalement assistée : perspectives islamiques
Authors: Guessous Nouzha 
Published: May 2023

La dissociation de la sexualité et de la reproduction, et la technicité et l’extériorisation croissantes de ces dernières par la médecine reproductive contemporaine, perturbent la procréation, la filiation et la parentalité. Cela soulève des questions éthiques, sociales et juridiques que les individus et les sociétés abordent en fonction de leur contexte social et culturel. En outre, ces nouvelles possibilités bouleversent les normes patriarcales qui sous-tendent les relations de genre, et remettent la sexualité et le corps des femmes au cœur du problème. Pourtant, les croyances culturelles et religieuses peuvent empêcher l’accès à certaines possibilités de procréation assistée, tandis que certaines de leurs utilisations peuvent conduire à de nouvelles formes de coercition et de discrimination contre les femmes. Qu’en est-il de la situation dans les sociétés musulmanes où les normes sociales juridiques et traditionnelles, essentiellement religieuses, peuvent entrer en conflit avec ces pratiques nouvellement accessibles ? Comment ces nouvelles possibilités de parentalité sont-elles comprises dans les sociétés musulmanes, où l’organisation sociale, la culture et les lois patriarcales restent prédominantes ? Quelles répercussions peuvent-elles avoir sur les droits des femmes et des enfants ? Cet article aborde ces questions à partir de perspectives historiques islamiques et à la lumière des besoins exprimés aujourd’hui par les musulmans à la recherche d’alternatives respectueuses des droits humains.
Corps et sexualité des femmes au Maroc entre les lois, la culture et les pratiques sociales
Authors: Tauil Leila 
Published: May 2023

Depuis des décennies, les féministes marocaines historiques réclament l’égalité des sexes à tous les niveaux de la société en dénonçant systématiquement le Code de la famille et le Code pénal qui les privent d’une égalité pleine et entière dans les sphères privées et publiques. Jusqu’au « printemps arabe », les questions liées au corps des femmes et à la sexualité étaient encore des sujets tabous, bien que ces questions soient au cœur du Maroc et de la majorité des sociétés musulmanes où « l’honneur des hommes dépend des corps des femmes ». Depuis les soulèvements au Maroc et dans le monde arabe, de jeunes féministes subversives n’hésitent plus à aborder publiquement la question du corps et de la sexualité en défendant le droit des femmes à disposer librement de leur corps. Le manifeste historique du collectif 490 « Hors-la-loi », publié au Maroc en septembre 2019 – équivalent au « Manifeste des 343 salopes en France » en 1971 – illustre parfaitement cette révolution en cours. Soutenus par un large éventail de la société civile, les auteurs de ce manifeste dénoncent le caractère obsolète des lois répressives pénalisant l’avortement et les relations sexuelles hors mariage qui poussent la société marocaine, divisée entre un projet social conservateur et moderne, à l’hypocrisie sociale et aux pratiques clandestines jugées illégales. Ce moment historique peut-il révéler les prémisses d’une véritable révolution égalitaire et démocratique au Maroc ?
L’influence de la diplomatie militaire sur la géopolitique en Amérique latine
Authors: Aparecido França Mauricio 
Published: May 2023

À côté de la diplomatie en sens strict, il avait la peine d’étudier le rôle des Forces Armées dans le processus de coopération régionale, ce qu’on appelle la « Diplomatie Militaire ». L’article analyse les principaux mécanismes de construction d’un système interaméricain de défense qui sont souvent très mal connus.
Covidtherm : le traitement thermal proposé aux personnes atteintes de Covid-long
Authors: Kanny Gisèle , Tallot Marie-Catherine , Danan Jane-Laure , Rossinot André , Bati Martine , Desfour Hugues , Goehringer François , N’Guyen Duc Trung , Kuntz Fabrice , Colin Xavier , Albuisson Eliane , Di Patrizio Paolo , Les membres du Conseil scientifique  
Published: May 2023

Le Grand-Est a été fortement touché lors de la première vague de l’épidémie de Covid-19. Dans les suites de la phase aiguë de la maladie sont apparus chez 5 à 10 % patients des symptômes persistants ou résurgents à type de fatigabilité intense, de maux de tête, de gêne respiratoire, de désadaptation à l’effort, perte d’odorat, douleurs musculosquelettiques, dénutrition, etc. La souffrance peut également s’exprimer sous forme d’angoisse, d’insomnie, d’états dépressifs voire d’un syndrome de stress post-traumatique. Dès mars 2020, la Fédération thermale du Grand-Est appelle à innover et à se réinventer pour répondre aux nouveaux besoins de santé face à la situation pandémique inédite. Le projet Covidtherm est initié pour mettre en œuvre dans les établissements thermaux, alors vides de tous curistes, une cure adaptée aux patients porteurs de symptômes persistants de la Covid-19 ; des soins d’accompagnement et de remise en forme des professionnels de santé épuisés physiquement et psychologiquement. La cure thermale offre le temps de repos essentiel pendant la phase de convalescence, permet la réappropriation des rythmes chronobiologiques dont le sommeil qui est le pilier de la récupération, la reprise d’une activité physique adaptée, la resocialisation. Elle constitue une unité de temps et de lieu propice à l’apprentissage de l’auto-gestion de la maladie. L’objectif de la cure thermale post-Covid-19 est de permettre aux patients de retrouver une autonomie, un équilibre psychologique, des capacités physiques, une vie sociale et professionnelle proche de celle de leur vie antérieure, de prévenir les séquelles au long cours par une action globale. La population cible correspond aux personnes souffrant de la persistance ou la résurgence des symptômes apparus de novo dans les suites de l’infection à Sars-Cov2 et persistants après 12 semaines. Le chemin thérapeutique repose sur un certain nombre d’invariants : (1) prescription de la cure Covidtherm par le médecin traitant, hospitalier ou spécialiste, avec transmission des éléments nécessaires à la continuité de la prise en charge ; (2) évaluation des besoins en soins par le médecin thermal, le kinésithérapeute, le psychologue et le diététicien prenant en compte les aspects sociaux et professionnels ; (3) mise en œuvre des soins de crénothérapie associés à des soins spécifiques adaptés aux symptômes. Les auteurs présentent le protocole d’évaluation du traitement thermal. Ce projet est une proposition thérapeutique innovante qui vise à mettre en place un parcours de soin adapté et répondre aux attentes des personnes atteintes de symptômes persistants au décours de la Covid-19 en situation d’errance médicale.
Development of an Integrated Library Management System (ILMS)
Authors: Ayo Eliza B. , Jotic Rommel N. , Raqueño Avelina , Loresca John Vincent G. , Mendoza Irene F. , Baroña Princess Vanessa M. 
Published: May 2023

Abstract— This document presents the design and development of an integrated library management system based on the needs assessment conducted in response to technology, infrastructure, existing condition, facilities, technology readiness of human resources, automation sufficiency level, and support of technical staff among ninety-eight (98) respondents using the descriptive developmental method.
Developing a system based on research is crucial in ensuring the accuracy and reliability of the system. This approach addresses specific problems or challenges by incorporating evidence-based practices and the latest advancements in the field.
The findings include the need to mentor the respondents on how to use technology and the influence of others as a factor in using technology. There is a difficulty encountered in navigating schools’ virtual libraries, unavailability of materials, and visiting it is not enticing anymore since information is available from the internet. The rarity of introducing new technology and the absence of 3D printers are common pain points. However, improvements on the library website, email/chat with a librarian, online research guides, online book reservations, and book delivery service were noticed. Research gaps and recommendations from the selected Library Management System were also employed as additional input in the development of the system. A deeper understanding of the Internet of Things, Artificial Intelligence, Big Data, Robotics, and Embedded Systems through training, webinars, and workshops are necessary for the librarian. These technologies could be applied in library operations and transactions. Procurement of the latest equipment which includes 3D printers and the development of integrated library systems are steps to take to improve the library's services and operation. By combining the results of assessments and incorporating new knowledge derived from research gaps and recommendations, provided a stronger foundation for the system. It also provides validation and grounding in scientific principles, ensuring that the system is well-informed and effective in its implementation. Ultimately, developing a system based on research leads to more informed and effective solutions to pain points and challenges.
Cancer Cells Promote Immune Regulatory Function of Macrophages by Upregulating Scavenger Receptor MARCO Expression
Authors: Gu Chao , Wiest Matthew , Zhang Wei , Halder Kuntal , Zurawski Sandy , Zurawski Gerard , Joo HyeMee , Oh SangKon 
Published: May 2023

Abstract
Expression of macrophage receptor with collagenous structure (MARCO) by tumor-associated macrophages is associated with poor prognosis of multiple types of cancer. In this article, we report that cancer cells (e.g., breast cancer and glioblastoma cell lines) can upregulate surface MARCO expression on human macrophages not only via IL-6–induced STAT3 activation but also via sphingosine-1-phosphate receptor (S1PR)-mediated IL-6 and IL-10 expression followed by STAT3 activation. We further found that MARCO ligation induces activation of the MEK/ERK/p90RSK/CREB signaling cascade, leading to IL-10 expression followed by STAT3-dependent PD-L1 upregulation. Such MARCO-induced macrophage polarization is accompanied by increased expression of PPARG, IRF4, IDO1, CCL17, and CCL22. Ligation of surface MARCO can thus result in decreased T cell responses mainly by reduction of their proliferation. Taken together, cancer cell–induced MARCO expression and its intrinsic regulatory function within macrophages are, to our knowledge, new aspects of cancer immune evasion mechanisms that need to be further studied in the future.
Surveillance of antimicrobial resistance in human health in Tanzania: 2016–2021
Authors: Camara Neema , Moremi Nyambura , Mghamba Janneth , Eliakimu Eliudi , Shumba Edwin , Ondoa Pascale , Egyir Beverly 
Published: May 2023

Background: Antimicrobial resistance (AMR) surveillance plays an important role in early detection of resistant strains of pathogens and informs treatments decisions at local, regional and national levels. In 2017, Tanzania developed a One Health AMR Surveillance Framework to guide establishment of AMR surveillance systems in the human and animal sectors.Aim: We reviewed AMR surveillance studies in Tanzania to document progress towards establishing an AMR surveillance system and determine effective strengthening strategies.Methods: We conducted a literature review on AMR studies conducted in Tanzania by searching Google Scholar, PubMed, and the websites of the Tanzania Ministry of Health and the World Health Organization for articles written in English and published from January 2012 to March 2021 using relevant search terms. Additionally, we reviewed applicable guidelines, plans, and reports from the Tanzanian Ministry of Health.Results: We reviewed 10 articles on AMR in Tanzania, where studies were conducted at hospitals in seven of Tanzania’s 26 regions between 2012 and 2019. Nine AMR sentinel sites had been established, and there was suitable and clear coordination under ‘One Health’. However, sharing of surveillance data between sectors had yet to be strengthened. Most studies documented high resistance rates of Gram-negative bacteria to third-generation cephalosporins. There were few laboratory staff who were well trained on AMR.Conclusion: Important progress has been made in establishing a useful, reliable AMR surveillance system. Challenges include a need to develop, implement and build investment case studies for the sustainability of AMR surveillance in Tanzania and ensure proper use of third-generation cephalosporins.What this study adds: This article adds to the knowledge base of AMR trends in Tanzania and progress made in the implementation of AMR surveillance in human health sector as a contribution to the global AMR initiatives to reduce AMR burden worldwide. It has highlighted key gaps that need policy and implementation level attention.
The performative function of turmoil, trauma and tenacity in Judith 9–16: A speech act analysis
Authors: Hobyane Risimati S. 
Published: May 2023

This article forms part of a larger project on the apocryphal Book of Judith. It explores the performative nature of turmoil, trauma and tenacity as found in the second half of the book (9–16). The impetus for this investigation is the work done by same author on chapters 1–8 of Judith while focusing on a similar theme. The present article suggests that the exploration of the turmoil, trauma and tenacity to be found in chapters 1–8 does not comprehensively represent all aspects that this topic has to offer to the reader of Judith. The contention here is that the theme of turmoil, trauma and the resultant tenacity in the second half of Judith needs further scholarly exploration as it reveals contrasting developments regarding two rivalling camps, that is, the Israelites and the Assyrians. From a speech act interpretive angle, the article asserts that turmoil, trauma and tenacity are intentionally utilised as a literary tool for indicating honour (Israelites) and shame (Assyrians). This has the potential to persuade the reader to make choices and/or decisions as they read the story.Contribution: The article is a continuation of my work on the first part of Judith (chapters 1–8), as indicated. Its main contribution rests on its unique approach to investigating the performative nature of trauma, turmoil and tenacity in the second part of the book, namely, chapters 9–16. The study of the theme of trauma, turmoil and tenacity in Judith is insightful and thought-provoking and does advance research around this fascinating book.
Comparison of central corneal thickness using anterior segment optical coherence tomography, ultrasound pachymetry, and orbscan
Authors: Khalil Nahla R. , Nagy Khaled A. , Sabry Moataz M. , Nasef Mohamed H. 
Published: May 2023

Background
The thickness of the cornea is a sensitive and important indicator for the health of the cornea. It is beneficial for evaluating endothelial pump function and corneal barrier, monitoring the disorders of the cornea such as keratoconus and corneal edema, and choosing patients for refractive surgery.

Aim
The aim of this work was to compare central corneal thickness (CCT) using orbscan, ultrasound pachymetry (USP), and anterior segment optical coherence tomography (AS-OCT).

Patients and methods
This prospective study was carried out on 60 eyes of 30 individuals aged from 18 to 40 years old and with clinically normal cornea who attended the outpatient clinic of Tanta University Hospital and Nour El Ein Hospital from April 2018 till March 2019.

Results
There was no statistically significant difference in mean minimal measurement of the thickness of the central cornea as measured by the three devices. There was a statistically significant difference in the mean maximal measurement of the CCT as detected by the three devices. The average CCT was statistically significantly different across the three devices.

Conclusions
OCT, USP, and orbscan were reliable for CCT measurement. Orbscan and USP were more reproducible, but OCT and ultrasound were more technically dependent. The average CCT was the highest by orbscan.
Percutaneous nephrolithotomy in patients with or without previous open nephrolithotomy from the same side
Authors: Qohaf Nader Abdel-Maksoud Elsaed , Hagres Ayman Mohammed , Taha Mohammed Rashid , Omer Mohammed Adel 
Published: May 2023

Background
Reintervention is typically difficult owing to perinephric anatomical changes in individuals with a history of open stone surgery.

Aim
The aim of the current study was to see what effect open renal surgery may have on the effectiveness and morbidity of later percutaneous nephrolithotomy (PCNL).

Patients and methods
PCNL was performed on 100 patients between March 2017 and March 2018. Overall, 20 of these patients were eliminated (tubeless or bilateral simultaneous PCNL). The remaining 80 patients were divided into two groups: 40 primary patients and the rest (history of open nephrolithotomy). Before intervention, a standard preoperative assessment was conducted. Statistical analysis was performed using SPSS v. 20 with the χ
2 test and the independent samples t-test. P value <0.05 was considered statistically significant.

Results
In terms of demographics and stone load, both groups were comparable. Group 1 had fewer attempts to access the pelvicalyceal system than group 2 (1.2 ± 0.5 vs. 2.7 ± 0.9, respectively), which was statistically significant (P=0.001*). Moreover, there was a statistically significant difference in the mean operational time between the two groups (85.24 ± 19.47 vs. 128.39 ± 17.45 min, respectively), with a statistically significant difference (P=0.001*). The rate of blood transfusion was similar in both groups (P=0.396). The remaining problems in both groups were similar.

Conclusion
Patients with renal stone surgery might require additional attempts to reach the pelvicalyceal system and may have difficulties with tract dilatation owing to retroperitoneal fibrosis. However, the overall morbidity and efficacy are the same in both groups.
Effect of adenoidal enlargement on development of otitis media with effusion
Authors: Metwally Ahmed S.M. , Amer Mohamed A.R. , Hagras Mahmoud A.G. , ElSherif Hossam S. 
Published: May 2023

Background
Adenoid hypertrophy has a major effect on development of middle ear effusion not due to the large volume but through combination of factors including local immune regulation, biofilm, and immunoglobulin E allergic reaction.

Aim
To assess the correlation between adenoid tissue volume and development of middle ear effusion.

Patients and methods
This was a sequential analysis study including a sample size of 195 patients from 4 to 12 years. They were diagnosed with adenoid hypertrophy, confirmed by flexible nasopharyngeal endoscopy (FNE) and lateral neck radiographs. They were evaluated by tympanometry to assess otitis media with effusion.

Results
We found that 59 (29.2%) patients had FNE grade 1, 68 (35.4%) patients had FNE grade 2, 68 (35.4%) patients had FNE grade 3, and no patients had grade 4. A total of 101 (52.6%) patients had a tympanogram type A and 94 (47.4%) patients had a tympanogram type B. There was no statistically significant correlation between tympanogram groups in relation to the FNE (P=0.762).

Conclusion
We suggested that there was no valuable correlation between change in size or volume of adenoid tissue and development of middle ear effusion.