bluuebunny/crossref_metadata_2025_split huggingface dataset:
Full Feedback Dynamic Neural Network with Exogenous Inputs for Dynamic Data‐Driven Modeling in Nonlinear Dynamic Power Systems
Authors: Zhang Zhenhui , Zhang Zhengjiang , Zhao Sheng , Hong Zhihui , Huang Shipei , Li Quanfang 
Published: April 2023

AbstractDynamic neural networks (DNNs) are widely used in data‐driven modeling of nonlinear control systems. Due to the complexity of the actual operating nonlinear power systems, rigorous dynamic models are always unknown. DNNs can focus on methods that only use input and output information to establish accurate dynamic models and reduce noise in measured data, which is called data‐driven modeling. The core of the DNN is the feedback with memory function. This paper analyzes the traditional Elman neural network (ENN) and nonlinear auto‐regression with exogenous input (NARX) neural network with different structure feedback structures, and proposes a full feedback dynamic neural network (FF‐DNN) with exogenous input. Eight different kinds of neural networks (including ENN, NARX, etc.) are compared and analyzed. The eight kinds of neural networks are applied on the experimental data of the DC‐AC inverter and the power system of Zhejiang Juchuang Smart Technology Company Park in Wenzhou. The experimental results are used to compare the performance of the data‐driven models established by eight different kinds of neural networks under different noise conditions, verify the robustness and generalization performance of dynamic data‐driven modeling based on FF‐DNN, and demonstrate the feasibility and effectiveness of FF‐DNN in actual power systems. © 2023 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC.
Enhancement of suppression oxidative stress and inflammation of quercetin by nano‐decoration for ameliorating silica‐induced pulmonary fibrosis
Authors: Yao Jingjing , Li Yuxuan , Meng Fei , Shen Wenwen , Wen Hao 
Published: April 2023

AbstractSilicosis is a life‐threatening lung fibrotic disease caused by excessive inhalation of environmental exposure to crystalline silica‐containing dust, whereas achieving therapeutic cures are constrained. Antioxidation and anti‐inflammation are currently recognized as effective strategies to counteract organ fibrosis. Using naturally occurring phytomedicines quercetin (Qu) has emerged in antagonizing fibrotic disorders involving oxidative stress and inflammation, but unfortunately the hydrophilicity deficiency. Herein, chitosan‐assisted encapsulation of Qu in nanoparticles (Qu/CS‐NPs) was first fabricated for silicosis‐associated fibrosis treatment by pulmonary delivery. Qu/CS‐NPs with spherical diameters of ~160 nm, demonstrated a high Qu encapsulated capability, excellent hydrophilic stability, fantastic oxidation radical scavenging action, and outstanding controlled as well as slow release Qu action. A silicosis rat model induced by intratracheal instillation silica was established to estimate the anti‐fibrosis effect of Qu/CS‐NPs. After intratracheal administration, CS‐NPs markedly enhanced Qu anti‐fibrotic therapy efficacy, accompanying the evident changes in reducing ROS and MDA production to mitigate oxidative stress, inhibiting IL‐1β and TNF‐α release, improving lung histological architecture, down‐regulating α‐SAM levels and suppressing ECM deposition, and thereby ameliorating silica‐induced pulmonary fibrosis. Results manifested that the augmented antioxidant and anti‐inflammatory activities of Qu by CS‐NPs delivery was a result of achieving this remarkable improvement in curative effects. Combined with negligible systemic toxicity, nano‐decorated Qu may provide a feasible therapeutic option for silicosis therapy.
Introduction
Authors: Earnshaw Rae 
Published: April 2023

AbstractHuman creators are capable of great feats of imagination and inventiveness. History and tradition testify to the masterpieces that have been produced over the centuries. Most of these have been created in human time with the tools that were available. The current digital revolution is providing a new set of tools and environments that creators can use, but this does raise issues such as to how best to preserve traditions and esthetic values that have been built up over many generations. Technology can provide both continuity and discontinuity which has both opportunities and challenges. A number of the factors influencing creativity are summarized, and suggestions made for evaluating the outcomes of the creative process. Mixed interdisciplinary environments offer opportunities for the production of creative works. The rise of commercial art for the Internet and interactive gaming is noted.
Digital Communication as a Creative Tool
Authors: Earnshaw Rae , Liggett Susan 
Published: April 2023

AbstractThe progress of computing and digital media is a relevant and useful case study in tools for creativity. Which visions of the future in the early days of computing have stood the test of time, and which have vanished without trace? Can this be used as guide for current and future areas of research and development? If one Internet year is equivalent to seven calendar years, are virtual worlds being utilized as an effective accelerator for these new creative ideas and their implementation and evaluation? The nature of digital media and its constituent parts which integrate technology and various forms of creative media provides a diverse environment which can be viewed as a testbed for current and future ideas. Individual disciplines utilize virtual worlds in different ways. As collaboration is often involved in such research environments, does the technology make these collaborations more creative and effective? Three Case Studies (European Projects) are included to illustrate how creativity can be enabled and stimulated in three kinds of collaborative virtual environments. Two further Case Studies are also included to illustrate how multimedia assets may be harnessed and made available to viewers.
Einleitung – die Unterrichtsnachbesprechung
Authors: Bührig-Hollmann Annette 
Published: April 2023

ZusammenfassungDie Unterrichtsnachbesprechung (UNB) in der zweiten Phase der Lehrerausbildung ist bisher nur ansatzweise empirisch erforscht. Mit der Rekonstruktion programmatischer Leitideen erwachsenenpädagogischer Prinzipien einerseits und den Positionierungen der Auszubildenden andererseits offenbaren sich diverse Spannungslagen in der Lehrkräfteausbildung. Neben der strukturell angelegten Doppelfunktion der Ausbildung (Beratung und Beurteilung) sind es vor allem diese unterschiedlichen Orientierungen der Beteiligten mit ihrer heterogenen Erwartungskultur, die die Kommunikation im Ausbildungskontext stören.
Die Lehrkräfteausbildung im Spiegel der Sozialforschung
Authors: Bührig-Hollmann Annette 
Published: April 2023

ZusammenfassungIn diesem Kapitel wird ein Überblick über Forschungsarbeiten zur Lehrer:innenausbildung gegeben. An dieser Stelle sei darauf hingewiesen, dass die Darstellung der hier zitierten Studien und Evaluationen keinen repräsentativen Überblick über den Forschungsstand zur Ausbildung im Vorbereitungsdienst leistet. Das Ziel ist vielmehr, die relevanten Fragestellungen und die damit verknüpften methodischen Herangehensweisen aufzuzeigen. Dies geschieht vor dem Hintergrund, die eigene Fragestellung und die daraus resultierenden methodischen Entscheidungen zur Datenerhebung und -auswertung einzuordnen und die getroffenen Entscheidungen nachvollziehbar zu machen.
The Critical Digital Model and Two Case Studies: the Churches of Santa Margherita and Santo Spirito in Bologna
Authors: Apollonio Fabrizio Ivan , Fallavollita Federico , Foschi Riccardo 
Published: April 2023

AbstractTwo case studies of hypothetical reconstruction are presented according to the principles of the Critical Digital Model [Apollonio et al. 2019]. One of the case studies is an architecture that was designed but never realized, and the other is the reconstruction of a historical art exhibition hosted into an architecture still existing today. This study is part of a wider research which is being currently carried out in the international Erasmus + project CoVHer. The main objective of the CoVHer project is to identify shared standards for the construction, evaluation and sharing of 3D hypothetical reconstructions. This research exploits the diversities of the two case studies to classify and re-define the methods of digital representation, which deal with the geometrical/mathematical nature of the models themselves and tries to define good practices to produce scientifically valid, sharable, and reusable 3D reconstructions.
Location attributes explaining the entry of firms in creative industries: evidence from France
Authors: Arauzo-Carod Josep-Maria , Coll-Martínez Eva , Turcu Camelia 
Published: April 2023

AbstractThis paper focuses on creative industries and the role played by the existing spatial distribution and agglomeration economies of these activities in relation to their entry decisions. We rely on employment and firm-level data in the creative industries (provided by INSEE) and compare the location of new establishments in the creative and non-creative industries between 2009 and 2013 in French departments (NUTS 3 regions). We use count data models and spatial econometrics to show that location determinants are rather similar in creative and non-creative industries and that specialisation in creative industries positively influences the entry of all other industries. The French case provides new insights to understand the geographical patterns of creative industries.
Imaging findings for response evaluation of ductal carcinoma in situ in breast cancer patients treated with neoadjuvant systemic therapy: a systematic review and meta-analysis
Authors: Ploumen Roxanne A. W. , de Mooij Cornelis M. , Gommers Suzanne , Keymeulen Kristien B. M. I. , Smidt Marjolein L. , van Nijnatten Thiemo J. A. 
Published: April 2023

Abstract
Objectives
In approximately 45% of invasive breast cancer (IBC) patients treated with neoadjuvant systemic therapy (NST), ductal carcinoma in situ (DCIS) is present. Recent studies suggest response of DCIS to NST. The aim of this systematic review and meta-analysis was to summarise and examine the current literature on imaging findings for different imaging modalities evaluating DCIS response to NST. More specifically, imaging findings of DCIS pre- and post-NST, and the effect of different pathological complete response (pCR) definitions, will be evaluated on mammography, breast MRI, and contrast-enhanced mammography (CEM).

Methods
PubMed and Embase databases were searched for studies investigating NST response of IBC, including information on DCIS. Imaging findings and response evaluation of DCIS were assessed for mammography, breast MRI, and CEM. A meta-analysis was conducted per imaging modality to calculate pooled sensitivity and specificity for detecting residual disease between pCR definition no residual invasive disease (ypT0/is) and no residual invasive or in situ disease (ypT0).

Results
Thirty-one studies were included. Calcifications on mammography are related to DCIS, but can persist despite complete response of DCIS. In 20 breast MRI studies, an average of 57% of residual DCIS showed enhancement. A meta-analysis of 17 breast MRI studies confirmed higher pooled sensitivity (0.86 versus 0.82) and lower pooled specificity (0.61 versus 0.68) for detection of residual disease when DCIS is considered pCR (ypT0/is). Three CEM studies suggest the potential benefit of simultaneous evaluation of calcifications and enhancement.

Conclusions and Clinical Relevance
Calcifications on mammography can remain despite complete response of DCIS, and residual DCIS does not always show enhancement on breast MRI and CEM. Moreover, pCR definition effects diagnostic performance of breast MRI. Given the lack of evidence on imaging findings of response of the DCIS component to NST, further research is demanded.

Key Points
• Ductal carcinoma in situ has shown to be responsive to neoadjuvant systemic therapy, but imaging studies mainly focus on response of the invasive tumour.
• The 31 included studies demonstrate that after neoadjuvant systemic therapy, calcifications on mammography can remain despite complete response of DCIS and residual DCIS does not always show enhancement on MRI and contrast-enhanced mammography.
• The definition of pCR has impact on the diagnostic performance of MRI in detecting residual disease,and when DCIS is considered pCR, pooled sensitivity was slightly higher and pooled specificity slightly lower.
Frictional Locomotion of a Radially Symmetric Tripedal Robot
Authors: Hermes Mark , Luhar Mitul 
Published: April 2023

AbstractThis study seeks to provide physical insight into the friction-driven crawling locomotion of systems with radially symmetric bodies. Laboratory experiments with a tripedal robot show that both translation and rotation can be achieved with just three independently actuated rigid limbs, i.e., with 3 degrees-of-freedom. These observations are rationalized using a simple mathematical model, which assumes that the friction at each limb is linearly proportional to the normal force at the contact point, and opposes the direction of motion. This dynamic model reproduces experimental observations across an extensive parametric sweep involving sinusoidal rotation of the limbs with varying amplitudes and phase shifts. Model predictions highlight the role played by time-varying normal forces at the contact points. These predictions are confirmed using embedded force transducers in the limbs. We present a further simplified analysis explaining that a geometric nonlinearity is induced in the dynamics from the radial symmetry and that this nonlinearity is essential to the generation of pure translation. We also show that this nonlinearity can be amplified by a cyclic time-varying limb length variation. These results provide a framework for further study of radially symmetric movers.
Sc2O3 on sapphire all-crystalline grating–waveguide resonant reflectors
Authors: Mourkioti Georgia , Bashir Danish , Govindassamy Goby A. , Li Fangfang , Eason Robert W. , Graf Thomas , Abdou Ahmed Marwan , Mackenzie Jacob I. 
Published: April 2023

AbstractThis paper reports the fabrication and first demonstration of all-dielectric crystalline grating–waveguide reflectors comprising a Sc2O3 waveguide grown on a sub-wavelength-patterned sapphire substrate. Rigorous coupled-wave analysis is employed to simulate the operation of the structure, suggesting a 100% resonance reflectivity in theory. Structuring of the sapphire substrate is achieved using inductively coupled plasma etching, whilst pulsed laser deposition is used for epitaxial growth of the Sc2O3 crystalline waveguide. Devices with distinct TE- and TM-polarisation resonances around 1030-nm for an angle of incidence near 10° are demonstrated, with reflectance approaching 90%. The discrepancy in reflectivity is attributed to the waveguide thickness variation and surface roughness. Refinement of the fabrication processes and tolerances should lead to improvement in the surface quality of the crystalline grating–waveguide structure and operation closer to the ideal resonance reflectivity.
Laparoscopic versus open resection of primary colorectal cancers and synchronous liver metastasis: a systematic review and meta-analysis
Authors: Morarasu Stefan , Clancy Cillian , Gorgun Emre , Yilmaz Sumeyye , Ivanecz Arpad , Kawakatsu Shoji , Musina Ana Maria , Velenciuc Natalia , Roata Cristian Ene , Dimofte Gabriel Mihail , Lunca Sorinel 
Published: April 2023

Abstract
Purpose
Combined resection of primary colorectal cancer and associated liver metastases is increasingly common. This study compares peri-operative and oncological outcomes according to surgical approach.

Methods
The study was registered with PROSPERO. A systematic search was performed for all comparative studies describing outcomes in patients that underwent laparoscopic versus open simultaneous resection of colorectal primary tumours and liver metastases. Data was extracted and analysed using a random effects model via Rev Man 5.3

Results
Twenty studies were included with a total of 2168 patients. A laparoscopic approach was performed in 620 patients and an open approach in 872. There was no difference in the groups for BMI (mean difference: 0.04, 95% CI: 0.63–0.70, p = 0.91), number of difficult liver segments (mean difference: 0.64, 95% CI:0.33–1.23, p = 0.18) or major liver resections (mean difference: 0.96, 95% CI: 0.69–1.35, p = 0.83). There were fewer liver lesions per operation in the laparoscopic group (mean difference 0.46, 95% CI: 0.13–0.79, p = 0.007). Laparoscopic surgery was associated with shorter length of stay (p < 0.00001) and less overall postoperative complications (p = 0.0002). There were similar R0 resection rates (p = 0.15) but less disease recurrence in the laparoscopic group (mean difference: 0.57, 95% CI:0.44–0.75, p < 0.0001).

Conclusion
Synchronous laparoscopic resection of primary colorectal cancers and liver metastases is a feasible approach in selected patients and does not demonstrate inferior peri-operative or oncological outcomes.
Late complications of cochlear implant: a case report of necrotizing meningoencephalitis similar to a CPA tumor
Authors: Di Rubbo Vittoria , Morelli Luca , Zangrandi Adriano , Lauda Lorenzo , Piras Gianluca , Sanna Mario 
Published: April 2023

Abstract
Objective
Report a case of localized necrotizing meningoencephalitis as the cause of functional hearing loss after cochlear implant (CI) surgery.

Case report
A 12-year-old with bilateral CI presented to our quaternary center due to severe functional hearing loss after 11 years since left ear CI surgery. CT with contrast was conducted showing a CPA tumor-like mass. Pre-operative computed tomography (CT) scans and magnetic resonance imaging (MRI) performed at the age of 1 year showed no inner ear abnormalities and in particular no evidence of a tumor in the cerebellopontine angle (CPA).

Conclusion
Following removal of the CI and the mass, histopathological, immunohistochemical and cultural examinations revealed a necrotizing meningoencephalitis, with the CI electrode as the focus.
Yearning for machine learning: applications for the classification and characterisation of senescence
Authors: Hughes Bethany K. , Wallis Ryan , Bishop Cleo L. 
Published: April 2023

AbstractSenescence is a widely appreciated tumour suppressive mechanism, which acts as a barrier to cancer development by arresting cell cycle progression in response to harmful stimuli. However, senescent cell accumulation becomes deleterious in aging and contributes to a wide range of age-related pathologies. Furthermore, senescence has beneficial roles and is associated with a growing list of normal physiological processes including wound healing and embryonic development. Therefore, the biological role of senescent cells has become increasingly nuanced and complex. The emergence of sophisticated, next-generation profiling technologies, such as single-cell RNA sequencing, has accelerated our understanding of the heterogeneity of senescence, with distinct final cell states emerging within models as well as between cell types and tissues. In order to explore data sets of increasing size and complexity, the senescence field has begun to employ machine learning (ML) methodologies to probe these intricacies. Most notably, ML has been used to aid the classification of cells as senescent, as well as to characterise the final senescence phenotypes. Here, we provide a background to the principles of ML tasks, as well as some of the most commonly used methodologies from both traditional and deep ML. We focus on the application of these within the context of senescence research, by addressing the utility of ML for the analysis of data from different laboratory technologies (microscopy, transcriptomics, proteomics, methylomics), as well as the potential within senolytic drug discovery. Together, we aim to highlight both the progress and potential for the application of ML within senescence research.
Shifting climate zones and expanding tropical and arid climate regions across Kenya (1980–2020)
Authors: Lawrence Ted J. , Vilbig Justin M. , Kangogo Geoffrey , Fèvre Eric M. , Deem Sharon L. , Gluecks Ilona , Sagan Vasit , Shacham Enbal 
Published: April 2023

Abstract
Human-induced climate change significantly alters the spatiotemporal characteristics of climate zones, which drives agricultural land use and ecosystem change. However, the detectability of shifting climate zones and the rate and time of the changes has yet to be adequately addressed at the regional-to-local scale. We mapped and analyzed changes to temperature and precipitation across Kenya during the past four decades, and linked those changes to shifts in the geographic distribution and arrangement of climate zones at regional scales. We observed an approximate 1 °C increase in average annual temperature over the 40-year period. A total of 76,346 km2 shifted from cooler to hotter zones, while 1298 km2 shifted from hotter to cooler zones. Tropical climate regions expanded from 91 to 93%, with over 13,000 km2 shifting from alpine and temperate to tropical regions. Average annual precipitation demonstrated little or no trend, but substantial spatial changes were observed. A total of 136,129 km2 shifted from wetter to drier zones, while 23,317 km2 shifted from drier to wetter zones. Arid climate regions expanded from 72 to 81%, a roughly 50,000 km2 shift from humid and semi-humid-to-semi-arid to arid regions. Overall, there was a 207,557 km2 shift in temperature and precipitation zones. As the climate zones predominately shift toward hotter and drier conditions, climatic diversity will decline, and in turn, ecosystem diversity and the ecosystem goods and services to society will decline. The changes also have broader global implications in terms of their contribution to global drylands as well as influencing earth system cycles. Overall, such information can better inform the Kenyan National Climate Change Response Strategy and be used to reach the UN Sustainable Development Goals.
Co-producing representations of summer rainfall in Bangladesh
Authors: Bremer Scott , Stiller-Reeve Mathew , Mamnun Nabir , Lazrus Heather 
Published: April 2023

AbstractClimate adaptation governance increasingly investigates the cultural capacities of communities to cope with climate variability and change. This paper reports on research of the symbolic representations of summer rainfall in the cultural repertoires guiding diverse institutionalised fields of activity in Sylhet Division. The research conducted interviews and co-created ‘cognitive maps’ with communities, to critically reflect on their changing seasonal symbols. The study revealed a common stock of summer symbols in Sylhet communities, which individuals reconfigure for strategizing and justifying particular practices. Symbols are stable but not static. As people’s uses of knowledge systems change—moving toward scientific representations—so too does their use of symbols. Moreover, environmental and climatic changes, such as a drying summer, are undermining long-held semiotic templates. Many local and traditional signs no longer hold, leaving communities without cultural templates for timely seasonal action. This work highlights the importance of cultural frameworks for organising communities’ seasonal adaptation, and the imperative for critically revisiting frameworks in rapid flux.