bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing and testing a protocol using a common data model for federated collection and analysis of national perinatal health indicators in Europe
Authors: Zeitlin Jennifer , Philibert Marianne , Estupiñán-Romero Francisco , Loghi Marzia , Sakkeus Luule , Draušnik Željka , Alcaide Adela Recio , Durox Mélanie , Cap Jan , Dimnjakovic Jelena , Misins Janis , Bernal Delgado Enrique , Thissen Martin , Gissler Mika ,   Euro-Peristat Research Group
Published: September 2023

Context: International comparisons of the health of mothers and babies provide essential benchmarks for guiding health practice and policy, but statistics are not routinely compiled in a comparable way. These data are especially critical during health emergencies, such as the coronavirus disease (COVID-19) pandemic. The Population Health Information Research Infrastructure (PHIRI) project aimed to promote the exchange of population data in Europe and included a Use Case on perinatal health. Objective: To develop and test a protocol for federated analysis of population birth data in Europe. Methods: The Euro-Peristat network with participants from 31 countries developed a Common Data Model (CDM) and R scripts to exchange and analyse aggregated data on perinatal indicators. Building on recommended Euro-Peristat indicators, complemented by a three-round consensus process, the network specified variables for a CDM and common outputs. The protocol was tested using routine birth data for 2015 to 2020; a survey was conducted assessing data provider experiences and opinions. Results: The CDM included 17 core data items for the testing phase and 18 for a future expanded phase. 28 countries and the four UK nations created individual person-level databases and ran R scripts to produce anonymous aggregate tables. Seven had all core items, 17 had 13-16, while eight had ≤12. Limitations were not having all items in the same database, required for this protocol. Infant death and mode of birth were most frequently missing. Countries took from under a day to several weeks to set up the CDM, after which the protocol was easy and quick to use. Conclusion: This open-source protocol enables rapid production and analysis of perinatal indicators and constitutes a roadmap for a sustainable European information system. It also provides minimum standards for improving national data systems and can be used in other countries to facilitate comparison of perinatal indicators.
Assessment of neonatal referral infrastructure and clinical characteristics of referred neonates in three first referral hospitals in Nairobi County, Kenya
Authors: Wainaina John , Irimu Grace , English Mike , Mbaire Emily , Waiyego Mary , Manyasi Christine , Kimutai David , Emadau Caren , Muturi Celia , Aluvaala Jalemba 
Published: September 2023

Background One in five newborns in Nairobi County, Kenya, may require inpatient neonatal care. We sought to examine referrals to and from three busy first-level referral public hospitals in Nairobi and what infrastructure and systems are available to support neonatal transport from these first-referral level hospitals to the main tertiary care center. Methods Patient-level data of newborns over 12 months were retrospectively extracted from routinely collected patient data and examined to characterize those referred into and out of three newborn units in the study hospitals. Structural assessments using a checklist completed during hospital visits were used to describe hospitals’ readiness to support newborn referral and transport. Results Five percent (398/7720) of the cohort studied were either referrals into study hospitals (68%, 272/398) or referrals out (32%, 126/398). Among 397 (99%) and 268 (67%) with sex and gestation documented respectively, 63% (251) were male and 44% (118) were preterm infants (<37 weeks). Among those referred in, 26% (69/272) died and 2.6% (7/272) were further referred to a tertiary-care newborn unit. Prematurity (39%) and birth asphyxia (29%) were the main in-referral reasons from 38 different health facilities, with specialist reviews (34%) predominant for out-referrals to a tertiary center. Diverse transport methods were used for referrals to study hospitals including private and public ambulances, vehicles, and on guardian’s arms while onward referrals to the tertiary center were done by hospital ambulances. Drugs and medical supplies required for stabilization were well available at the study sites, however, only oxygen nasal cannula, nasal prongs, and face masks were available in the ambulance of hospital 3. Conclusion There is a need to develop, equip, and maintain a high-quality referral and newborn transport system that can support the continuum of newborn care across referral care pathways into and from first-referral level hospitals.
PERCEPÇÕES DE BOLSISTAS E VOLUNTÁRIOS DO IFMT CAMPUS CONFRESA SOBRE A PESQUISA NA FORMAÇÃO INICIAL DE PROFESSORES DE CIÊNCIAS
Authors: Nascimento Dhennife Almeida , Alves Ana Claudia Tasinaffo , Leão Marcelo Franco 
Published: September 2023

O estudo objetivou compreender as percepções dos acadêmicos e egressos de cursos de licenciatura que participaram de projetos de pesquisa do IFMT Campus Confresa sobre a importância da pesquisa para sua formação inicial e no preparo para a docência. O estudo do tipo exploratório e descritivo utilizou um formulário eletrônico para coletar dados de 20 acadêmicos que tiveram vínculo com projetos de pesquisa de 2010 a 2020. A investigação ocorreu no início de 2021, constituído por 12 perguntas, sendo 03 abertas e 09 fechadas. Todos afirmaram que atividades com pesquisa contribuíram em sua formação. A maioria respondeu que a pesquisa é essencial e impacta positivamente na atuação profissional. A participação proporcionou diferentes vivências e para o aperfeiçoamento de competências, como a investigação, sistematização e argumentação, necessárias na atuação profissional.
O QUE HÁ DE CIÊNCIA NA FESTA JUNINA? DO MILHO AO PINHÃO
Authors: Silva dos Santos Cíntia Daniele , Goldschmidt Andréa Inês 
Published: September 2023

O artigo aborda o desenvolvimento e avaliação de uma sequência de ensino investigativa (SEI) sobre o tema festas juninas, em especial sobre o pinhão. Desenvolvida com 20 alunos de anos iniciais de uma escola pública do Estado do Rio Grande do Sul. O objetivo foi compreender as relações entre festa junina e ensino de ciências, através da origem e importância do pinhão, tratando aspectos da cultura alimentar, nutricionais, ecológicos e educacionais, sendo um recurso ambiental disponível, e que o ato de comer essa semente deve promover reflexões sobre seu consumo, plantio e preservação da espécie. O artigo apresenta um recorte da SEI desenvolvida, com resultados provenientes de dois dos cinco módulos componentes: módulo 1: “Contextualização do tema central: festa junina – do milho ao pinhão”; e, módulo 2: “Pinhão: qual a importância nutricional dele? Como ele é disseminado na natureza? Qual a importância ecológica?. A abordagem foi o ensino por investigação em Ciências, que propiciou aos alunos não apenas o contato com os conteúdos programáticos necessários à sua etapa educativa, mas a possibilidade da multidisciplinaridade com as diferentes áreas do conhecimento trabalhadas na escola, tendo como eixo articulador a ciência. Destaca-se nas atividades a curiosidade, ludicidade, investigação, observação e o desenvolvimento da argumentação acerca dos conhecimentos adquiridos sobre a necessidade da preservação do bioma mata atlântica e da mata das araucárias, não apenas para o consumo de pinhões nas festas juninas, mas para a sobrevivência e manutenção ecológica da diversidade de espécies que vivem nesse local, consumindo também esse alimento.
POESIA E LETRAMENTO LITERÁRIO: RELATO DE CURSO DE EXTENSÃO ONLINE PARA PROFESSORES DOS ANOS INICIAIS
Authors: Leal Ana Claudia de Macena Freitas D'Estillac , Amparo Flavia Vieira da Silva do 
Published: September 2023

O artigo se propõe a relatar uma experiência pedagógica realizada por meio de curso de extensão online para professores dos Anos Iniciais do Ensino Fundamental. Teve como problema: de que forma a abordagem estética do gênero poético pode contribuir para o letramento literário de crianças dos Anos Iniciais do Ensino Fundamental? Trata-se de uma pesquisa-ação com o objetivo geral de favorecer a formação de docentes dos Anos Iniciais do Ensino Fundamental e propor práticas de letramento literário em sala de aula. Apoiou-se nas referências de Cosson (2019) sobre letramento literário; em Pinheiro (2020) sobre o estudo de poemas na sala de aula; e na aprendizagem do poético e do sensível, pela perspectiva de Morin (2017) e Petit (2009). A proposta do curso foi oferecer a possibilidade do professor refletir sobre sua prática e trocar experiências acerca do ensino de literatura, com foco na poesia, em turmas dos Anos Iniciais do Ensino Fundamental. Os participantes puderam conhecer abordagens contemporâneas sobre o ensino de literatura, e sobre propostas para trabalhar a poesia na sala de aula, discutiram o conceito de letramento literário e refletiram sobre práticas que podem favorecer a formação do leitor. Os dados coletados nas atividades síncronas e assíncronas foram analisados de acordo com a metodologia da Análise do Discurso (AD). Pode-se dizer que o curso ofereceu subsídios aos professores e incentivo a práticas de letramento literário que valorizam elementos estéticos como critério de escolha de livros e autores, explorando outros sentidos do texto poético com leitores iniciantes.
Professores(as) formadores(as) e suas percepções sobre a matemática na educação infantil: elementos para um projeto formativo
Authors: Ciríaco Klinger Teodoro , Santos Cicero Augusto dos 
Published: September 2023

Este artigo é fruto de uma investigação, de Iniciação Científica, financiada pela Fundação de Amparo à Pesquisa do Estado de São Paulo – FAPESP (Processo N. 2019/10135-7), desenvolvida na Universidade Federal de São Carlos (UFSCar) no "Mancala – Grupo de estudos e pesquisas em educação matemática, cultura e formação docente" (CNPq). Para este fim, a abordagem metodológica foi de natureza qualitativa e os dados foram produzidos com base em entrevistas semiestruturadas com um professor e uma professora, ambos ensinam matemática na licenciautra em pedagogia em instituições paulistas. A discussão teórica toma como referência estudos sobre a educação infantil, educação matemática na infância e o perfil de professores(as) formadores(as). Os resultados, decorrente das informações possibilitadas via entrevistas, constataram que os(as) formadores(as) afirmam que a licenciatura em questão necessita ampliar as discussões acerca do conceito de "criança" e das especificidades curriculares dos primeiros anos de vida em uma ampla relação com os pressupostos da educação da infância, isso porque consideram ser relevante perceber que não é papel da educação infantil escolarizar, mas sim pensar um currículo matemático mediado pelas interações e a brincadeira.
Identification and experimental validation of key extracellular proteins as potential targets in intervertebral disc degeneration
Authors: Zhang Guang-Zhi , Li Lei , Luo Zhang-Bin , Zhang Cang-Yu , Wang Yong-Gang , Kang Xue-Wen 
Published: September 2023

AimsThis study aimed, through bioinformatics analysis and in vitro experiment validation, to identify the key extracellular proteins of intervertebral disc degeneration (IDD).MethodsThe gene expression profile of GSE23130 was downloaded from the Gene Expression Omnibus (GEO) database. Extracellular protein-differentially expressed genes (EP-DEGs) were screened by protein annotation databases, and we used Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) to analyze the functions and pathways of EP-DEGs. STRING and Cytoscape were used to construct protein-protein interaction (PPI) networks and identify hub EP-DEGs. NetworkAnalyst was used to analyze transcription factors (TFs) and microRNAs (miRNAs) that regulate hub EP-DEGs. A search of the Drug Signatures Database (DSigDB) for hub EP-DEGs revealed multiple drug molecules and drug-target interactions.ResultsA total of 56 EP-DEGs were identified in the differential expression analysis. EP-DEGs were enriched in the extracellular structure organization, ageing, collagen-activated signalling pathway, PI3K-Akt signalling pathway, and AGE-RAGE signalling pathway. PPI network analysis showed that the top ten hub EP-DEGs are closely related to IDD. Correlation analysis also demonstrated a significant correlation between the ten hub EP-DEGs (p＜0.05), which were selected to construct TF–gene interaction and TF–miRNA coregulatory networks. In addition, ten candidate drugs were screened for the treatment of IDD.ConclusionThe findings clarify the roles of extracellular proteins in IDD and highlight their potential as promising novel therapeutic targets.Cite this article: Bone Joint Res 2023;12(9):522–535.
Estimating the Effects of Political Instability in Nascent Democracies
Authors: Emery Thomas J. , Kovac Mitja , Spruk Rok 
Published: September 2023

Abstract
In this paper, we revisit and examine the effect of political instability on institutional quality. To this end, we exploit the crackdown of government cabinet in 2008 that led to almost two decades of pervasive political instability using the unique case of Slovenia and estimate the average treatment effect of political instability and the missing counterfactual scenario for the period 1996–2020. Based on large-scale Bayesian analysis with Metropolis–Hastings algorithm, we extract the residual component of institutional quality from the variation in predetermined unobserved characteristics. Across more than 1.5 million sequenced random samples, we construct novel time-varying estimates of institutional quality at the local and regional level. Our difference-in-differences and synthetic control estimates emphasize a rampant deterioration of institutional quality in response to political instability with evidence of weakened rule of law, less effective public sector, decreased political accountability, and more widespread prevalence of power abuses. The estimated negative effects of political instability are robust to a variety of placebo checks across more than 12 billion placebo averages for institutional quality outcome variable using random sampling method of treatment permutation.
A systematic literature review of undiscovered vulnerabilities and tools in smart contract technology
Authors: Zaazaa Oualid , El Bakkali Hanan 
Published: September 2023

AbstractIn recent years, smart contract technology has garnered significant attention due to its ability to address trust issues that traditional technologies have long struggled with. However, like any evolving technology, smart contracts are not immune to vulnerabilities, and some remain underexplored, often eluding detection by existing vulnerability assessment tools. In this article, we have performed a systematic literature review of all the scientific research and papers conducted between 2016 and 2021. The main objective of this work is to identify what vulnerabilities and smart contract technologies have not been well studied. In addition, we list all the datasets used by previous researchers that can help researchers in building more efficient machine-learning models in the future. In addition, comparisons are drawn among the smart contract analysis tools by considering various features. Finally, various future directions are also discussed in the field of smart contracts that can help researchers to set the direction for future research in this domain.
The polyA tail facilitates splicing of last introns with weak 3′ splice sites via PABPN1
Authors: Huang Li , Li Guangnan , Du Chen , Jia Yu , Yang Jiayi , Fan Weiliang , Xu Yong‐Zhen , Cheng Hong , Zhou Yu 
Published: September 2023

AbstractThe polyA tail of mRNAs is important for many aspects of RNA metabolism. However, whether and how it regulates pre‐mRNA splicing is still unknown. Here, we report that the polyA tail acts as a splicing enhancer for the last intron via the nuclear polyA binding protein PABPN1 in HeLa cells. PABPN1‐depletion induces the retention of a group of introns with a weaker 3′ splice site, and they show a strong 3′‐end bias and mainly locate in nuclear speckles. The polyA tail is essential for PABPN1‐enhanced last intron splicing and functions in a length‐dependent manner. Tethering PABPN1 to nonpolyadenylated transcripts also promotes splicing, suggesting a direct role for PABPN1 in splicing regulation. Using TurboID‐MS, we construct the PABPN1 interactome, including many spliceosomal and RNA‐binding proteins. Specifically, PABPN1 can recruit RBM26&27 to promote splicing by interacting with the coiled‐coil and RRM domain of RBM27. PABPN1‐regulated terminal intron splicing is conserved in mice. Together, our study establishes a novel mode of post‐transcriptional splicing regulation via the polyA tail and PABPN1.
Beyond singability: A descriptive-explanatory analysis of Polish translations of Frank Sinatra's My Way
Authors: Rędzioch-Korkuz Anna 
Published: September 2023

AbstractTranslation and music has become a subfield within translation studies oriented towards discussing singable song translations. Most studies in this subfield have been lyrics-oriented, emphasising lack of semantic fidelity resulting mainly from issues of singability. Though singability is an important factor influencing song translation, song texts function as coherent compositions in wider contexts of time and place, their performers or poetics of translators. This article aims to present a multimodal and comparative analysis of three Polish song translations of Frank Sinatra's My Way. By adopting a descriptive-explanatory approach it demonstrates how the interplay of performer-related, contextual, social or poetics-based factors can be more influential than singability.
Translation procedures in secondary term formation across languages in online glossaries: Universal or language-specific?
Authors: Polcz Károly , Hamsovszki Szvetlana , Huszár Erika , Jámbor Emőke , Szigetváry Nóra , Válóczi Marianna 
Published: September 2023

AbstractOnline terminological glossaries may play a key role in translating and disseminating terms in multiple languages, especially in those highly specialized domains where no other terminological sources are available. The influence of English as a lingua franca is undeniable in the process of shaping target language terminologies. The purpose of this paper is to explore types of secondary term formation and the related translation procedures as reflected in specialized online glossaries in the domain of start-up companies to find out whether they are universal or language-specific. The study investigates 28 online glossaries in five languages with a total of 1,566 terms. It is hypothesised that contact-based term formation with a considerable influence of English is significantly more frequent than interpretative term formation with little or no such influence. It is also proposed that among the translation procedures transference is of the highest occurrence. According to the third hypothesis, languages differ in their preference for various translation procedures. Statistical tests have confirmed all three hypotheses. In addition, our findings also shed light on the lexical gaps in the target languages under investigation.
Exploring the relevance and relative importance of interpreting aptitude constructs and their underlying factors: A data-driven tripartite investigation
Authors: Liu Yubo , Zhang Wei 
Published: September 2023

AbstractThis study aims to explore the relevance and underlying factors of an array of interpreting aptitude constructs, and, on that basis, the collective and group-specific perception of their relative importance. To meet the research purposes, a questionnaire survey was designed and distributed to interpreting trainers, trainees and professional interpreters, asking respondents to evaluate the relative importance of 40 aptitude constructs drawn from an extensive literature review. A total of 769 valid responses were collected. An explorative factor analysis retained 23 constructs divided into three factors focusing on cognitive skills for online information processing, personality traits and temperaments, and foundational linguistic skills respectively. While personality traits and temperaments were regarded as a stable and distinctive dimension of interpreting aptitude, cognitive skills for information processing were viewed as the most important factor. Particularly, listening and speaking in B enjoyed the highest rating. Although statistically significant differences existed in the relative importance of certain constructs, the substantive differences indicated by the effect sizes were small. Compared with trainees, trainers and professional interpreters demonstrated a more sharpened awareness of market demands and industrial priorities, but otherwise the three groups converged more than they diverged in the evaluation of aptitude constructs and factors.
ARE BLOOD GROUPS EFFECTIVE IN INFERTILITY? EVALUATION OF 8-YEAR DATA FROM A TERTIARY CENTER
Authors: ULUSOY KARATOPUK Dilek , ÇELİKYÜREK Muazzez 
Published: September 2023

Objective
The aim is to compare blood groups between spontaneously
pregnant fertile patients and infertile female
patients undergoing treatment for infertility diagnosis
is defined as the failure to achieve pregnancy despite
regular unprotected sexual intercourse for one year
during the reproductive period without using any contraceptive
method.
Material and Method
Our study includes statistically evaluating the blood
groups and demographic data of a total of 608 patients,
including 304 fertile patients who presented for
routine pregnancy follow-up at the Department of Obstetrics
and Gynecology, Süleyman Demirel University,
between January 2015 and January 2023, and 304
infertile patients receiving treatment at the Süleyman
Demirel University Assisted Reproductive Techniques
(ART) Center.
Results
The mean age of the volunteers in the fertile group
was calculated as 30.68±4.70, while the mean age of
the volunteers in the infertile group was 32.50±5.35.
Blood group A was found to be dominant in both the
fertile and infertile groups, followed by blood groups
O, B, and AB. When compared based on education,
it was determined that the majority of patients in the
infertile group had received undergraduate or postgraduate
education. Income levels were categorized as
low, medium, and high income based on occupational
distributions in both groups, revealing that the majority
of participants in both groups had a low-income level.
Conclusion
Infertility is a multifactorial condition resulting from a
combination of various factors such as genetics, environment,
lifestyle, and health. The prevalence of infertility
increases with age, and blood group distribution
does not have a direct impact on infertility.