bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fecal antibiotic resistance genes were transferred through the distribution of soil-lettuce-snail foodchain
Authors: Zhang Yuan , Zhao Jiayi , Chen Minglong , Tang Xinyue , Wang Yijia , Zou Yun 
Published: April 2023

Abstract
Massive antibiotic resistance genes (ARG) were detected in the soil modified by manure, which may affect human life safety through the food chain. However, the transmission of ARGs through the soil-plant-animal food chain is still unclear. Therefore, this study used high-throughput quantitative PCR technology to explore the effects of pig manure application on ARGs and bacterial communities in soil, lettuce phyllosphere and snail excrement.The results showed that a total of 384 ARGs and 48 MEGs were detected in all samples after 75 days of incubation. The diversity of ARGs and MGEs in soil components increased significantly by 87.04%and 40%with the addition of pig manure. The absolute abundance of ARGs in the phyllosphere of lettuce was significantly higher than that of the control group, with a growth rate of 212.5%.Six common ARGs were detected between the three components of the fertilization group, indicating that there was internal transmission of fecal ARGs between the trophic levels of the food chain.Firmicutes and Proteobacteria were identified as the dominant host bacteria in the food chain system, which were more likely to be used as carriers of ARGs to promote the spread of resistance in the food chain.The results were used to evaluate the potential ecological risks of livestock and poultry manure and provide theoretical basis and scientific support for the formulation of ARGs prevention and control policies.
Effect of aluminizing and laser shock peening on high temperature oxidation resistance of AISI 321 stainless steel for solar thermal power generation heat exchanger
Authors: Li Wei , Qin Wenyang , Jiang Dapeng , Bo Guowei , Ni Song , Chen Hui , Zhao Yilin , Huang Weiying , Peng Xulong , He Jianjun , Ren Yanjie , Li Cong , Zhou Libo , Zhang Shengde , Chen Jian 
Published: April 2023

Abstract
The high-temperature oxidation resistance of AISI 321 stainless steel for solar thermal power generation heat exchanger highly determines its service life. Therefore, in this work, aluminizing treatment and aluminizing with subsequent laser shock peening (LSP) were employed to improve the high-temperature oxidation resistance of AISI 321 stainless steel at 620°C. The results showed that these two treatments decreased the oxidation rate as compared to the base AISI 321 steel. Concretely, the optimal oxidation resistance was observed in the aluminized steel before an oxidation testing time of 144 h due to the increased the entropy of the LSP-treated specimen. After 144 h, however, the LSP-treated sample showed the best oxidation resistance because of the formation of protective α-Al2O3. For the LSP-treated samples, the large amount of sub-grain boundaries formed on aluminized layer could act as the fast short-circuit path for the outward diffusion of Al element, facilitating the rapid nucleation of α- Al2O3. Meanwhile, the aluminized layer is able to isolate the contact between oxidation environment and matrix, thereby decreasing the oxidation rate. Further, the oxidation parabolic constant D(t) of LSP-treated steel was calculated to be minimum (6.45787×10–14), which is respectively 69.18% and 36.36% of aluminized steel and 321 steel during the whole oxidation process. Consequently, the combination of aluminizing and LSP can better improve the high-temperature oxidation resistance of 321 stainless steel.
Catalytic Performance of Single-Atom Catalysts M1/PW12O40 for Alkyne Hydrogenation
Authors: Talib Shamraiz , Jiang Xuelian , Feng Shixiang , Zhao Mengdie , Yu Qi 
Published: April 2023

AbstractSingle-atom catalysts (SACs) have provoked significant curiosity in heterogeneous catalysis due to the benefits of maximum metal atoms usage, robust metal-support interaction, single-metal-atom active sites, and high catalytic efficiency. Transition metal (M1) adatoms anchored on highly stable phosphotungstic acid (PTA) cluster (Scheme 1) provide an opportunity for altering their electronic, magnetic and catalytic characteristics. In this study, the electronic structures and catalytic mechanism of ethyne hydrogenation of SACs with the group-9 metal atoms M1(M1= Co, Rh, Ir) anchored on PTA cluster have been explored by using first-principles quantum calculations. It is found that the catalytic activity of ethyne hydrogenation is determined by two critical parameters: the adsorption energies of the adsorbate (H2, C2H2) and the activation energy barrier of ethyne hydrogenation. We have shown that the reaction pathway of ethyne hydrogenation reaction on the experimentally characterized Rh1/PTA at room temperature consists of three steps: C2H2and H2coadsorption on Rh1/PTA, H2attacking C2H2to form C2H4, then C2H4desorbing or further reacting with H2to produce C2H6and completing the catalytic cycle. The Rh1/PTA possesses fair catalytic activity with C2H4desorption energy of 1.46 eV at the rate determining step and high selectivity for ethylene formation through the Langmuir−Hinshelwood mechanism. The potentially competitive mechanism for the formation of ethane is not kinetically favorable, with a 2.59 eV barrier for ethylene hydrogenation. Moreover, micro-kinetics analysis is also carried out to further understand the mechanism and catalytic performance. The work reveals that the PTA supported SACs can be a promising catalyst for alkyne hydrogenation.
Comparison of Plasma Oxytocin Level in Women With Natural and Surgical Menopause
Authors: Korkmaz Hilal , Deveci Canan Dura , üstün yusuf , pehlivanoğlu bilge 
Published: April 2023

Abstract
Objective We aimed to investigate plasma oxytocin level in women with natural and surgical menopause and its relation with other metabolic parameters.Methods This study included 89 postmenopausal women admitted to menopausal outpatient clinics and gave written consent to participate. Participants were allocated into natural (Group 1; n = 61) and surgical (Group 2; n = 28) menopause groups based on causative process for the onset of menopause. After the clinical evaluation and physical examination, blood samples are collected for biochemical profile and plasma oxytocin levels. The complete blood count, lipid profile, thyroid panel, blood glucose concentration, vitamin D and liver enzymes were measured by autoanalyzer, plasma oxytocin level was measured spectrophotometrically by ELISA method.Results The groups were comparable for age, body mass index, menopause duration, gravity and blood parameters measured except significantly different plasma oxytocin levels between the two groups as 6.8 (3.2–20.6) ng/ml in natural menopause group and 4.2 (2.9–18.2) ng/ml in surgical menopause group (p < 0.001). Plasma oxytocin level was also negatively correlated with age (r = -0.245, p = 0.022) and menopausal duration (r = -0.275, p = 0.01).Conclusion Our results point out that oxytocin might be a target hormone to manage menopause associated disorders and/or it should be considered for its role in the differences in the incidences of postmenopausal diseases and quality of life in the course of natural and surgical menopausal transition.
Effect of Ixekizumab on Enthesitis-related arthritis non-responsive to anti-TNF treatment, a case report
Authors: Zheng Qi , Ma Xiaohui , Zhong Mengmeng , Zhang Yan , Lu Meiping 
Published: April 2023

AbstractBackground:To describe the effectiveness of Ixekizumab on a patient with ERA who was refractory to conventional treatment and TNF inhibitors.Case presentation:A 15-year-old boy who manifested as swollen knees, bilateral ankle arthritis, sausage toes and low-grade fever was diagnosed as Enthesitis related arthritis. There was one episode of uveitis three years before the onset of joint symptoms. The patient had a high level of inflammation (ESR to 107 mm/hour, CRP to 248.77 mg/L) with increased level of serum IL-6 and VEGF. Combination therapy of NSAIDs with sulfasalazine, Adalimumab, Infliximab, low dose steroid, Golimumab and Tofacitinib were applied correspondingly. The systemic inflammation of this patient (not including swollen toes and enthesitis) got a little better with oral steroids, but intensified again when steroid was weaned. Ixekizumab (80mg, Q2W twice, then 80mg Q4W) combined with oral methotrexate were then applied for this patient. ESR and CRP decreased into normal level with quick alleviation of arthritis within the first month of treatment. A persistent clinical remission was achieved by using Ixekizumab in the following two years of therapy. Apart from slight redness and swelling at the injection site, no significant side effects were observed during follow up.Conclusion:Ixekizumab can be a substitutive therapy for ERA patients who were unresponsive to traditional therapy or anti-TNF treatment.
Clinical characteristics and surgical outcomes of pediatric idiopathic and secondary macular epiretinal membrane
Authors: Liu Jing-hua , Wang Qian , Li Song-feng , Deng Guang-da , Ma Jing , Li Liang , Yuan Mingzhen , Lu Hai 
Published: April 2023

Abstract
Background: To describe and compare the different clinical characteristics and surgical outcomes of patients with pediatric idiopathic and secondary macular epiretinal membranes (ERMs).
Methods: A cohort of pediatric patients (≤14years) underwent surgical removal of macular ERMs were selected from January 2019 to September 2021. Those patients were grouped into idiopathic macular ERMs group and secondary macular ERMs group, medical data including ocular manifestations were assessed and compared preoperatively and postoperatively.
Results :A total of 41 patients (50 eyes) were included, mean age at surgery was 6.5 years (3～14 years), mean follow-up duration was 19.5months (12～31 months). Fourteen of the 41 patients (34.1%) had idiopathic macular ERMs. Compared with secondary macular ERMs, pediatric idiopathic ERMs had an older age at surgery(p=0.032) and were mostly found fortuitously by school visual acuity (VA) screening(p=0.028) with more cases with appearance of cellophane macular reflex (p=0.047); on OCT images, idiopathic macular ERMs were more likely to have taco folds (p=0.031)and less ellipsoid zone (EZ) disruptions (p=0.026) ; idiopathic macular ERMs were more likely to have better preoperative best corrected visual acuity (BCVA)(p<0.001); surgical removal of pediatric macular ERMs results in VA improvement with less postoperative complications in pediatric idiopathic ERMs.
Conclusion: Pediatric idiopathic macular ERMs have many different clinical characteristics compared with that of pediatric secondary macular ERMs; surgical removal of pediatric macular ERMs results in VA improvement with less postoperative complications in pediatric idiopathic ERMs.
Trial registration: Retrospective case series study, not applicable. NCT2378898
MYCT1 inhibits hematopoiesis in diffuse large B-cell lymphoma by suppressing RUNX1 transcription
Authors: Fu Wei-Neng , Liang Ying , Wei Xin , Yue Peng-Jie , Zhang Hecheng , Li Zhen-Ning , Sun Yuan-Yuan 
Published: April 2023

Abstract
Abnormality of the chromosomal karyotype is one factor causing poor prognosis in patients with lymphoma. Here, in the analysis of the abnormal karyotype of lymphoma patients, the three smallest overlapregions were found, in which MYCT1 was located. MYCT1 was first cloned by our research team as tumor suppressor gene, but studies related to the occurrence and development of lymphoma have not been reported. In this study, we found MYCT1 could inhibit proliferation and promote cell cycle arrest in diffuse large B-cell lymphoma cells. Moreover, we demonstrate that MYCT1 represses RUNX1 transcription by binding MAX. The findings provide clues and a basis for in-depth studies of MYCT1 in the diagnosis, treatment and prognosis of lymphoma.
The mediating role of mental vulnerability between negative life events and interaction anxiousness
Authors: Gong Yuxin 
Published: April 2023

Abstract
Purpose: The study aims to analyze the relationships between mental vulnerability, negative life events and interaction anxiousness among undergraduate students in China and examine the mediating role of mental vulnerability on undergraduate students.
Methods: A cross-sectional survey target for undergraduate students in Liaoning province. The sample included 1,238 college students. Pearson correlation coefficient, multiple linear regression and structural equation modeling method were applied to analyze the data.
Results: The results suggest that mental vulnerability played a partial mediating role
between negative life events and interaction anxiousness among undergraduate students.Negative life events had a significant indirect effect on the interaction anxiousness
through mental vulnerability.
Conclusions: The study result will contribute to improve the physical and mental health development of undergraduate students.
Scour Analysis in a Climate Change Context Using Artificial Neural Networks
Authors: Baron Edward Alexis , Bento Ana Margarida , Matos José Campos e , Calçada Rui , Gavin Kenneth 
Published: April 2023

Abstract
Global climate change can create uncertainty and affect local weather patterns, which in turn can increase the frequency and severity of extreme weather events such as flooding. Flooding is considered one of the major causes of bridge collapse and it is important to ensure the safety and functionality of these structures against such hazards. This paper presents a methodology for an artificial neural network that can estimate peak flow discharge by analyzing a projected precipitation database and considering various parameters related to climate change uncertainties. The results of the machine learning model can then be used in a hydraulic model to identify flood-prone areas and estimate hydraulic parameters such as flow velocity and water column height using a geographic information system. In addition, the methodology can evaluate the most significant and recurring impact of flooding on bridges, namely the scouring process. The proposed methodology was tested in a masonry arch bridge case study in Portugal. The results show the effectiveness of the methodology in predicting flood risk and assessing the potential impact on bridge safety and functionality.
Conservative endodontic microsurgery to protect critical anatomical structures--Selective curettage: A case series
Authors: Li Nan , Zhang Rui , Qiao Weiwei , Meng Liuyan 
Published: April 2023

Abstract
Endodontic microsurgery has obtained highly successful outcomes in preserving teeth with persistent or recurrent periapical periodontitis that nonsurgical endodontic treatments do not work. To avoid complications in conditions that periapical lesions invade anatomical structures such as nasopalatine nerve tube, mandibular canal, selective curettage has been proposed as an alternative choice of complete curettage in surgery. This case series presented 8 cases, which underwent selective curettage for adjacent critical anatomical structures were involved in the periapical periodontitis radiographically, and those cases were confirmed as periapical cysts or granulomas by biopsy. At least 1 year’s clinical and radiographic follow-ups showed complete or incomplete healing in these cases with no adverse effects.
Pyomyositis associated with abscess formation caused by Streptococcus Pneumoniae in children: a case report and review of literature
Authors: Barchi Luca , Fastiggi Michele , Bassoli Ilaria , Bonvicini Federico , Silvotti Monica , Iughetti Lorenzo , De Fanti Alessandro 
Published: April 2023

Abstract
Background Pyomyositis is an unusual bacterial infection but potential severe in children. Staphylococcus Aureus is the main caused of this disease (70–90%), following by Streptococcus Pyogenes (4–16%). Streptococcus Pneumoniae rarely caused invasive muscular infections. We describe a case of pyomyositis caused by Streptococcus Pneumonia in an adolescent 12-year-old female.Case presentation: I.L. referred to our hospital for high fever associated with right hip and abdominal pain. The blood exams showed increase of leukocytes with prevalence of neutrophils with high level of inflammatory markers (CRP 46,17 mg/dl; Procalcitonin 25,8 ng/ml). The abdomen ultrasonography was unremarkable. The CT and MRI of the abdomen and right hip revealed pyomyositis of the iliopsoas, piriformis and internal shutter associated with collection of pus between the muscular planes (Fig. 1). The patient was admitted to our paediatric care unit, and she was initially treatment with intravenous Ceftriaxone (100mg/kg/die) and Vancomycin (60mg/kg/die). On day 2, a pansensitive Streptococcus Pneumoniae was isolated from the blood culture, and the antibiotic treatment was changed to only IV Ceftriaxone. She was successively treated with IV Ceftriaxone for 3 weeks, then continued with oral Amoxicillin for a total of 6 weeks of therapy. The follow up showed a complete resolution of the pyomyositis and psoas abscess after 2 months.Conclusion Pyomyositis associate with abscess is a rare and very dangerous disease in children. The clinical presentation can mimic symptoms of other pathologies like osteomyelitis or septic arthritis, so many times is hard to identify. The main risk factors include story of recent trauma and immunodeficiency, not present in our case report. The therapy involves the antibiotics and, if possible, abscess drainage. In literature there is much discussion about duration of antibiotic therapy
The supply of macro- and microelements to cotton plants at different distances from the pipes of fertilizer production factory
Authors: Litvinovich Andrey , Lavrishchev Anton , Bure Vladimir , Zhapparova Aigul , Saljnikov Elmira 
Published: April 2023

Abstract

Environmental pollution from industrial plants via air deposition is a globally urgent problem. The article presents the study of the influence of dust and gas emissions from a factory for the production of mineral fertilizers on cotton plants in Uzbekistan. The composition of technogenic dust deposited on plant leaves has been determined. The chemical composition of the above-ground and underground organs of cotton at different distances from the source of pollution has been established. The radius of aerial dispersion of industrial emissions was best described by measurements of the fluorine content in washed and unwashed cotton leaves. Empirical models have been developed that describe the relationship between P, K, Mg, Ca, S, F, and Mn in plant roots and leaves depending on the distance to the pollution source. The results of biometric observations were summarized and the yield of raw cotton was established. Zones of different levels of technogenic load on cotton plants were identified. It has been shown that the resistance of cotton against aerial pollution by acid gases (SO2 and H2S) from the emissions is determined by the ability of cotton plants to neutralize toxic compounds of their transformation by increasing the influx of alkaline earth metals to the affected tissues. This study showed the possibility of growing cotton in the vicinity of the fertilizer factory. Despite the resistance of cotton to industrial pollution, monitoring of areas identified as impact zones is recommended.
Deaggregation of Probabilistic Seismic Hazard for Designated Cities in Ghana
Authors: Ahulu Sylvanus Tetteh , Gidigasu Solomon Senyo , Nuamah Daniel 
Published: April 2023

Abstract
A probabilistic seismic hazard study based on the values of spectral acceleration (SA), and peak ground acceleration (PGA) has been performed for the southern part of Ghana. Three conceivable seismic sources inside and near Ghana were identified and considered based on a modern and integrated earthquake catalog of over a century (1615–2009). Epistemic uncertainties associated with input parameters were considered and implemented in the seismic hazard calculation using a logic tree method. These included the chosen suitable ground-motion attenuation equations. Thereafter, the deaggregation of the seismic hazard, expressed in magnitude and distance, for selected cities in Ghana was estimated to aid in the understanding of the contributions to the hazard of various seismic sources. Deaggregation of the seismic hazard was estimated for SA of 0.2 s, and 1.0 s as well as PGA at 10% probability of exceedance in 50 years. All in all, the results show that the sources located close to the cities contribute most to their seismic hazard, especially for PGA. More distance sources only contribute to the hazard at longer periods (e.g. 1.0s) The importance of the outcome of this type of study is that deaggregation of the seismic hazard offers valuable data of the seismic sources that contribute towards the hazard at a specific location. This information can be used to decide on the scenario-based ground-motion time histories necessary for the seismic design of structures.
Health Systems Interventions for Prevention of Maternal Peripartum Infection in Low and Middle Income Countries: A Systematic Review
Authors: Abwao Roseline , Mapesa Job , Tenambergen Wanja , Odada David , Gathoni Nasra , Riunga Felix 
Published: April 2023

Abstract

Background
Maternal peripartum infection is still a widespread avoidable problem in Low and Middle Income countries (LMICs) despite developments in postnatal care. Lately systems approach, encompassing all the factors in the health system, is being recognized as ameliorate option for the improvement of maternal health and prevention of maternal mortality.
Objective:The aim of this systematic review was to identify and evaluate interventions to prevent maternal peripartum infection in LMICs.
Methods -The Cochrane Library, CINAHL, MEDLINE (via PubMed) and Scopus,World Health Organization (WHO) ,the National Institute for Health and Care Excellence (NICE) websites were searched to identify interventional studies to prevent maternal peripartum infection using the PRISMA model. The article searching was conducted for a period of 3 months (01/08/2022 to 30/10/2022). Search terms were “Peripartum”, “Infection”, “Genital tract”, and their MESH terms. The inclusion criteria were primary studies that reported interventions for the prevention of maternal peripartum infection, studies from LMICs and those written in English language. Cochrane Risk of Bias tools were used to appraise the quality of the studies.
Results – From 1662 article results,29 articles were included covering 56,151 participants. The interventions were grouped into six domains: antibiotic prophylaxis 11(37.9% of studies), self-care training 6 (20.6%), skin preparation 6 (20.6%), systems approach 2 (6.9%), Traditional Birth Attendant training (6.9 %) and use of Clean Delivery Kit 2(6.9%).12 studies reported a significantly lower risk of infection. Six studies reported a significantly improved knowledge and practice of women regarding maternal peripartum infection. Two studies reported no change in the risk of infection.
Conclusion- There is limited research from LMICs on interventions to prevent maternal peripartum infection, however the studies are of good quality. The study identified six domains of interventions which were mainly inpatient settings targeting maternal peripartum infection in isolation without consideration of other system components. This provides an opportunity for achieving optimum reduction in maternal peripartum infection though systems approach. Health systems interventional studies are therefore needed to further the gains in maternal peripartum infections prevention in LMICs.
Study registration: PROSPERO CRD42022342550