bluuebunny/crossref_metadata_2025_split huggingface dataset:
Introducing the Condor Array Telescope. I. Motivation, Configuration, and Performance
Authors: Lanzetta Kenneth M. , Gromoll Stefan , Shara Michael M. , Berg Stephen , Valls-Gabaud David , Walter Frederick M. , Webb John K. 
Published: January 2023

Abstract
The “Condor Array Telescope” or “Condor” is a high-performance “array telescope” comprised of six apochromatic refracting telescopes of objective diameter 180 mm, each equipped with a large-format, very low-read-noise (≈1.2 e−), very rapid-read-time (<1 s) CMOS camera. Condor is located at a very dark astronomical site in the southwest corner of New Mexico, at the Dark Sky New Mexico observatory near Animas, roughly midway between (and more than 150 km from either) Tucson and El Paso. Condor enjoys a wide field of view (2.29 × 1.53 deg2 or 3.50 deg2), is optimized for measuring both point sources and extended, very low-surface-brightness features, and for broad-band images can operate at a cadence of 60 s (or even less) while remaining sky-noise limited with a duty cycle near 100%. In its normal mode of operation, Condor obtains broad-band exposures of exposure time 60 s over dwell times spanning dozens or hundreds of hours. In this way, Condor builds up deep, sensitive images while simultaneously monitoring tens or hundreds of thousands of point sources per field at a cadence of 60 s. Condor is also equipped with diffraction gratings and with a set of He ii 468.6 nm, [O iii] 500.7 nm, He i 587.5 nm, Hα 656.3 nm, [N ii] 658.4 nm, and [S ii] 671.6 nm narrow-band filters, allowing it to address a variety of broad- and narrow-band science issues. Given its unique capabilities, Condor can access regions of “astronomical discovery space” that have never before been studied. Here we introduce Condor and describe various aspects of its performance.
Interaction of moiré excitons with cavity photons in two-dimensional semiconductor hetero-bilayers
Authors: Gao Yuchen , Ye Yu 
Published: January 2023

Abstract
Moiré materials, composed of two single-layer two-dimensional semiconductors, are important because they are good platforms for studying strongly correlated physics. Among them, moiré materials based on transition metal dichalcogenides (TMDs) have been intensively studied. The hetero-bilayer can support moiré interlayer excitons if there is a small twist angle or small lattice constant difference between the TMDs in the hetero-bilayer and form a type-II band alignment. The coupling of moiré interlayer excitons to cavity modes can induce exotic phenomena. Here, we review recent advances in the coupling of moiré interlayer excitons to cavities, and comment on the current difficulties and possible future research directions in this field.
Investigation on bio-sourced textile reinforcement for composite material based on sisal Moroccan yarns
Authors: Samouh Z , Abed A , Cochrane C , Labanieh A R , Boussu F , Soulat D , El-Mozznine R , Cherkaoui O 
Published: January 2023

Abstract
The main objective of this paper aims at investigating the potential use of sisal yarn into composite material despite the inherent variability of properties of natural resources. A multi-scale approach of the behavior of sisal fiber woven reinforcements is conducted to understand and evaluate the different properties of woven reinforcements. At the yarn scale, a piezo-resistive sensor yarn was developed to assess deformations and stress concentrations in-situ in order to understand the material behavior during the weaving of woven reinforcements fibrous for bio-sourced composite materials. At the fabric scale, 2D woven reinforcements are developed based on a conventional weaving process. The production and characterization of composite sheets based on 2D woven reinforcements show the potential of sisal fiber woven reinforcements compared to natural fiber woven reinforcements from literature.
Towards commercialization of graphene-based end-of-life sensors for fire-protective fabrics
Authors: Yehia D , Lawson L , King D , Chung H-J , Batcheller J , Dolez P I 
Published: January 2023

Abstract
Fire-resistant (FR) fabrics used in protective clothing experience a reduction in performance as a result of exposure to various ageing conditions, for instance: heat, ultraviolet (UV) light, moisture, abrasion and laundering procedures. However, there are few visible clues to indicate if the deterioration of the protective clothing has reached a dangerous level. To address this issue, graphene-based end-of-life sensors (heat, UV light, and moisture) are being developed at the University of Alberta in collaboration with five industry partners, including Davey Textile Solutions, Inc (DTS). DTS has the production capacity to manufacture the graphene-based end-of-life sensors, including weaving, finishing, conductive track application, fusing, and product assembly. The lifetime of fire-protective clothing is an important parameter to monitor, and the graphene-based end-of-life sensors are a straightforward, non-destructive, and effective tool for this purpose. The plan is to fabricate, integrate and commercialize the sensors. DTS, alongside academic researchers from the University of Alberta, are in the process of scaling up the manufacturing and testing of the sensors. The health and safety of firefighters will be improved by bringing graphene-based end-of-life sensors to the market.
Loop Fabric EEG Textrode for Brain Activity Monitoring
Authors: Tseghai G B , Malengier B , Fante K A , Langenhove L Van 
Published: January 2023

Abstract
Recently, metallic dry EEG electrodes have been introduced to overcome the limitation of wet electrodes, as the conductive gel used causes skin irritation and dries out over time. However, the metal dry EEG electrodes have a high weight and a stiff structure that limits them from wearable application. In this work, we have developed a textile-based EEG electrode (textrode) from silver-plated polyamide loop fabric washable up to 100 cycles. The new EEG textrode collects quality signals comparable to commercial dry Ag/AgCl EEG electrodes. The signals were detected at all major EEG bandwidths. In addition, the new textrodes showed a lower skin-to-electrode impedance (-19.23%) than the commercial dry electrode and a higher signal-to-noise ratio (+27.4%). Therefore, these novel textile-based electrodes can be used to monitor brain activity for wearable applications, especially when long-term monitoring is required.
Structural and optical variation of pseudoisocyanine aggregates nucleated on DNA substrates
Authors: Chiriboga Matthew , Green Christopher M , Mathur Divita , Hastman David A , Melinger Joseph S , Veneziano Remi , Medintz Igor L , Díaz Sebastián A 
Published: January 2023

Abstract
Coherently coupled pseudoisocyanine (PIC) dye aggregates have demonstrated the ability to delocalize electronic excitations and ultimately migrate excitons with much higher efficiency than similar designs where excitations are isolated to individual chromophores. Here, we report initial evidence of a new type of PIC aggregate, formed through heterogeneous nucleation on DNA oligonucleotides, displaying photophysical properties that differ significantly from previously reported aggregates. This new aggregate, which we call the super aggregate (SA) due to the need for elevated dye excess to form it, is clearly differentiated from previously reported aggregates by spectroscopic and biophysical characterization. In emission spectra, the SA exhibits peak narrowing and, in some cases, significant quantum yield variation, indicative of stronger coupling in cyanine dyes. The SA was further characterized with circular dichroism and atomic force microscopy observing unique features depending on the DNA substrate. Then by integrating an AlexaFluorTM 647 (AF) dye as an energy transfer acceptor into the system, we observed mixed energy transfer characteristics using the different DNA. For example, SA formed with a rigid DNA double crossover tile (DX-tile) substrate resulted in AF emission sensitization. While SA formed with more flexible non-DX-tile DNA (i.e. duplex and single strand DNA) resulted in AF emission quenching. These combined characterizations strongly imply that DNA-based PIC aggregate properties can be controlled through simple modifications to the DNA substrate’s sequence and geometry. Ultimately, we aim to inform rational design principles for future device prototyping. For example, one key conclusion of the study is that the high absorbance cross-section and efficient energy transfer observed with rigid substrates made for better photonic antennae, compared to flexible DNA substrates.
Climate change and macro-financial risks: financial policy responses for an orderly low-carbon transition
Authors: D’Orazio Paola 
Published: January 2023

Abstract
Climate-related financial policies (CRFPs) are needed to tame potential climate-related financial risks deriving from climate change and to finance the low-carbon transition. International engagement levels and CRFP adoption are currently too low to encourage an adequate low-carbon transition and protect the financial system from materializing climate risks. Therefore, greater global commitment is especially important as the COP27 will likely uphold the 1.5 ∘C targets while following the Intergovernmental Panel on Climate Change’s advice to keep global warming below 2 ∘C. Despite the recent rapid proliferation of the literature on climate-related financial policymaking, some important knowledge gaps remain. Additional investigation, particularly in financial disclosure and stress tests, climate-aligned macro-prudential policies aimed at financial capital, climate data availability, and new research approaches, is required to help decision-makers achieve orderly and swift decarbonization.
Left-sided valvular heart disease in dialysis recipients: a single-centre observational study
Authors: Elewa Mohamed , Mitra Sandip , Jayanti Anuradha 
Published: January 2023

ABSTRACT

Background
With the increasing prevalence of chronic kidney disease, the number of people receiving renal replacement is expected to increase by 50% by 2030. Cardiovascular mortality remains significantly higher in this population. The presence of valvular heart disease (VHD) in patients with end-stage renal disease is associated with poor survival. In a dialysis cohort, we assessed the prevalence and characteristics of patients with significant VHD, the association with clinical parameters and the impact on survival.

Methods
Echocardiographic parameters for dialysis recipients from a single centre in the UK were collected. Significant left-sided heart disease (LSHD) was defined as moderate or severe left valvular lesions or left ventricular systolic dysfunction (LVSD) (ejection fraction &lt;45%) or both. Baseline demographic and clinical characteristics were ascertained.

Results
In 521 dialysis recipients {median age 61 years [interquartile range (IQR) 50–72], 59% male}, 88% were on haemodialysis and the median dialysis vintage was 2.8 years (IQR 1.6–4.6). A total of 238 (46%) had evidence of LSHD: 102 had VHD, 63 had LVSD and 73 had both. Overall, 34% had evidence of left-sided VHD. In multivariable regression analysis, age and use of cinacalcet were associated with higher odds of VHD {odds ratio [OR] 1.03 [95% confidence interval (CI) 1.02–1.05] and OR 1.85 [95% CI 1.06–3.23], respectively}, while the use of phosphate binders was associated with increased odds of aortic stenosis [AS; OR 2.64 (95% CI 1.26–5.79)]. The 1-year survival was lower in VHD [78% versus 86% (95% CI 0.72–0.84 and 0.83–0.90), respectively] and in LSHD [78% versus 88% (95% CI 0.73–0.83 and 0.85–0.92), respectively]. In AS, the 1-year survival was 64% (95% CI 0.49–0.82). Using propensity score matching to adjust for age, diabetes and low serum albumin, AS was significantly associated with lower survival (P = .01). LSHD was significantly associated with worse survival (P = .008) compared with survival in LVSD (P = .054).

Conclusion
A high proportion of dialysis patients have clinically significant LSHD. This was associated with higher mortality. In valvular heart disease, the development of AS is independently associated with higher mortality in dialysis patients.
Case report: a transcatheter aortic valve replacement failure secondary to COVID-19 infection
Authors: Tacon P Ryan , Cao Louie , Birkeland Kade , Kedan Ilan 
Published: January 2023

AbstractBackgroundValve thrombosis is a well-documented cause of bioprosthetic valve failure. Case reports have been published of prosthetic valve thrombosis secondary to COVID-19 infection. This is the first case report of COVID-19 associated valve thrombosis in a patient with transcatheter aortic valve replacement (TAVR).Case summaryA 90-year-old female with atrial fibrillation on therapeutic apixaban and status-post TAVR presented with COVID-19 infection and was found to have severe bioprosthetic valvular regurgitation with features suggestive of valve thrombosis. She underwent valve-in-valve TAVR with resolution of valvular dysfunction.DiscussionThis case report contributes to a growing body of evidence describing the occurrence of thrombotic complications in patients with valve replacement and COVID-19 infection. Increased vigilance and continued investigation are warranted to better characterize thrombotic risk and to inform optimal antithrombotic strategies during COVID-19 infection.
Older Adults’ User Engagement With Mobile Health: A Systematic Review of Qualitative and Mixed-Methods Studies
Authors: van Acker Justine , Maenhout Laura , Compernolle Sofie 
Published: January 2023

AbstractBackground and ObjectivesThe aging population places increasing demands on our healthcare system. Mobile health offers the potential to reduce this burden. The aim of this systematic review is to thematically synthesize qualitative evidence of older adults’ user engagement toward mobile health, and to generate relevant recommendations for intervention developers.Research Design and MethodsA systematic literature search was performed in Medline, Embase, and Web of Science electronic databases from inception until February 2021. Papers on qualitative and mixed-methods studies that investigated older adults’ user engagement with a mobile health intervention were included. Relevant data were extracted and analyzed using thematic analysis. The Critical Appraisal Skills Program Qualitative Checklist was used to assess the quality of the included studies.ResultsThirty-two articles were deemed eligible for inclusion in the review. Three overarching analytical themes emerged from the 25 descriptive themes generated by the line-by-line coding: the limited capabilities, the prerequisite of motivation, and the importance of social support.Discussion and ImplicationsSuccessful development and implementation of future mobile health intervention for older adults will be challenging given the physical and psychological limitations and motivational barriers that older adults experience. Design adaptations and well-thought-out blended alternatives (i.e., combining mobile health with face-to-face support) might be potential solutions to improve older adults’ user engagement with mobile health interventions.
Reflection and transmission of plane waves in stressed media with an imperfectly bonded interface
Authors: Li Wenqiang , Hu Hengshan 
Published: January 2023

SUMMARY
The reflection and transmission of elastic waves are of great significance for predicting reservoir physical properties, interpreting seismic data and detecting crustal structures. Most studies only consider the initial vertical stress state when studying the reflection and transmission of elastic waves at imperfectly bonded interfaces, but few studies consider the influence of initial stress on boundary conditions. Moreover, the effect of initial stress on the energy distribution of elastic waves at imperfectly bonded interfaces has rarely been investigated. We propose a unified method to calculate the energy reflection and transmission coefficients for different incident waves at welded or imperfectly bonded interfaces in stressed media. The effects of initial stress on the equation of motion, the elastic properties of the medium and the boundary conditions at the interface are considered. The elastic properties of rocks under initial stress are described by acoustoelasticity theory. In addition, we define a new stress tensor to modify the linear-slip model for describing boundary conditions at the imperfectly bonded interface in the presence of initial stress. Numerical results show that the energy reflection and transmission coefficients at the non-welded interface in stressed media depend on the elastic properties of the incident and transmitted media, the initial stress, the type and magnitude of the interfacial compliance and the frequency and propagation direction of the incident wave. The initial vertical and horizontal stresses dominate the reflection and transmission coefficients at small and large angles, respectively. The discontinuity in displacement across the imperfectly bonded boundary results in the frequency dependence of the reflection and transmission coefficients. Imperfect bonding enhances P-wave and SV-wave energy reflection and weakens P-wave energy transmission. However, imperfect bonding can enhance the energy transmission of the SV wave for the imperfectly bonded interface with high contrast between tangential and normal compliance and a resonance peak appears at a specific frequency. We also notice that imperfectly bonded interfaces with interfacial compliance less than $1.0 \times {10}^{ - 11}$ m Pa−1 can be regarded as welded interfaces in the seismic frequency band (lower than 100 Hz). In addition, the initial stress greatly influences the reflection coefficients at high frequencies and the transmission coefficients at low frequencies. The initial vertical stress can reduce the energy transmission of SV waves at imperfectly bonded interfaces. In contrast, the initial horizontal stress can significantly increase the energy transmission of low-frequency SV waves and may lead to the disappearance of the resonant peak in the transmission coefficients.
The role of DNA methylation in the maintenance of phenotypic variation induced by grafting chimerism inBrassica
Authors: Liu Ke , Wang Tingjin , Xiao Duohong , Liu Bin , Yang Yang , Xu Kexin , Qi Zhenyu , Wang Yan , Li Junxing , Xiang Xun , Yuan Lu , Chen Liping 
Published: January 2023

AbstractGrafting facilitates the interaction between heterologous cells with different genomes, resulting in abundant phenotypic variation, which provides opportunities for crop improvement. However, how grafting-induced variation occurs and is transmitted to progeny remains elusive. A graft chimera, especially a periclinal chimera, which has genetically distinct cell layers throughout the plant, is an excellent model to probe the molecular mechanisms of grafting-induced variation maintenance. Here we regenerated a plant from the T-cell layer of a periclinal chimera, TCC (where the apical meristem was artificially divided into three cell layers – from outside to inside, L1, L2, and L3; T = Tuber mustard, C = red Cabbage), named rTTT0 (r = regenerated). Compared with the control (rsTTT, s = self-grafted), rTTT0 had multiple phenotypic variations, especially leaf shape variation, which could be maintained in sexual progeny. Transcriptomes were analyzed and 58 phenotypic variation-associated genes were identified. Whole-genome bisulfite sequencing analyses revealed that the methylome of rTTT0 was changed, and the CG methylation level was significantly increased by 8.74%. In rTTT0, the coding gene bodies are hypermethylated in the CG context, while their promoter regions are hypomethylated in the non-CG context. DNA methylation changes in the leaf shape variation-associated coding genes, ARF10, IAA20, ROF1, and TPR2, were maintained for five generations of rTTT0. Interestingly, grafting chimerism also affected transcription of the microRNA gene (MIR), among which the DNA methylation levels of the promoters of three MIRs associated with leaf shape variation were changed in rTTT0, and the DNA methylation modification of MIR319 was maintained to the fifth generation of selfed progeny of rTTT0 (rTTT5). These findings demonstrate that DNA methylation of coding and non-coding genes plays an important role in heterologous cell interaction-induced variation formation and its transgenerational inheritance.
A randomized superiority clinical trial: metronidazole improved the efficacy of high-dose dual therapy inHelicobacter pylorirescue treatment
Authors: Ding Zhao-Hui , Huang Yu , Chen Jin-Nan , Luo Lai-Sheng , Zhang Wei , Liang Xiao , Lu Hong 
Published: January 2023

AbstractBackground and objectivesHigh-dose dual therapy [proton pump inhibitor (PPI) + amoxicillin] is recommended as a Helicobacter pylori rescue treatment. However, its efficacy is still controversial. The aim of this study was to evaluate the efficacy and safety of triple therapy containing high dose of PPI and amoxicillin plus metronidazole compared with dual therapy in rescue treatment.MethodsTwo hundred and sixty-eight patients who failed at least two courses of H. pylori treatment were recruited and randomly allocated into two 14-day groups: esomeprazole 40 mg twice daily and amoxicillin 1000 mg three times daily plus metronidazole 400 mg three times daily (EAM group); or esomeprazole 40 mg twice daily and amoxicillin 1000 mg three times daily (EA group). The agar-dilution method was performed as an antibiotic susceptibility test. The 13C urea breath test was used to assess H. pylori eradication at 6 weeks after the treatment. The study was registered at clinicaltrials.gov (NCT04024527).ResultsH. pylori eradication rates in the EAM group were 85.8% (115/134, 95% CI 79.9%–91.7%) in ITT analysis and 92.6% (113/122, 95% CI 87.9%–97.3%) in PP analysis, significantly higher than those of the EA group, which were 73.1% (98/134, 95% CI 65.6%–80.6%) and 83.1% (98/118, 95% CI 76.8%–89.8%) (P = 0.005, 0.011). Resistance rates of amoxicillin and metronidazole were 6.6% (13/196) and 89.8% (176/196). Metronidazole resistance did not affect the eradication rates in the EAM group. Both groups had similar moderate and severe adverse events and similar compliance.ConclusionsA triple therapy containing high dose of PPI and amoxicillin plus metronidazole could be a potential rescue therapy worldwide even in a high metronidazole-resistance region.
Recommendations for Epstein-Barr virus–based screening for nasopharyngeal cancer in high- and intermediate-risk regions
Authors: Lam W K Jacky , King Ann D , Miller Jacob A , Liu Zhiwei , Yu Kelly J , Chua Melvin L K , Ma Brigette B Y , Chen Ming Yuan , Pinsky Benjamin A , Lou Pei-Jen , Woo John K S , Hsu Wan-Lun , Simon Julia , Doolan Denise L , Waterboer Tim , Hui Edwin P , Li Hui , Tsang Raymond K , Wong Kenneth C W , Goh Julian P , Vlantis Alexander C , Ai Qi Yong , Wong Lun M , Abdullah Victor , Lin Jin Ching , Chen Chien-Jen , Pfeiffer Ruth M , Le Quynh-Thu , Lee Anne W M , Ji Mingfang , Cao Sumei , Ma Jun , Chan Anthony T C , Chan K C Allen , Hildesheim Allan 
Published: January 2023

AbstractA meeting of experts was held in November 2021 to review and discuss available data on performance of Epstein-Barr virus (EBV)–based approaches to screen for early stage nasopharyngeal carcinoma (NPC) and methods for the investigation and management of screen-positive individuals. Serum EBV antibody and plasma EBV DNA testing methods were considered. Both approaches were found to have favorable performance characteristics and to be cost-effective in high-risk populations. In addition to endoscopy, use of magnetic resonance imaging (MRI) to investigate screen-positive individuals was found to increase the sensitivity of NPC detection with minimal impact on cost-effectiveness of the screening program.