bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Prospective, Randomized, Open-Label, Active-Controlled Study to Compare the Efficacy and Safety of Levocetirizine and Bepotastine in Chronic Spontaneous Urticaria
Authors: Menghani Gaurav , Kaur Navneet , Vyas Kapil , Gupta Kalpana , Maheshwari Kriti , Singh Raju 
Published: May 2023

Background:
Management of chronic spontaneous urticaria (CSU) is challenging because of its unpredictable course and negative influence on the quality of life. Second-generation antihistaminics are the first-line treatment. Levocetirizine, a time-tested antihistaminic, has proven efficacy in CSU. Bepotastine, which was previously used for allergic rhinitis and conjunctivitis, has recently been tried in urticaria. It may be a better alternative to levocetirizine because of its long-term safety.

Objectives:
The aim of this study was to compare the efficacy and safety of levocetirizine and bepotastine in CSU.

Materials and Methods:
A randomized, active-controlled, open-label, prospective, interventional study was conducted on 70 patients of CSU. After initial clinical assessment and baseline investigations, bepotastine and levocetirizine were prescribed to separate groups of 35 patients for a period of 12 weeks. Urticaria Activity Score (UAS) and Dermatology Life Quality Index (DLQI) were used for assessing the severity of disease. Follow-up visits were planned for evaluating clinical improvement and adverse effects. Results were compared using Mann–Whitney U test and Fisher’s exact test. P < 0.05 was considered statistically significant.

Results:
The reduction in UAS and DLQI score in levocetirizine group was better than bepotastine group, and the results were statistically significant at 12 weeks (P = 0.0001). Incidence of adverse effects such as sedation and weight gain was higher in levocetirizine group at 12th week (P = 0.0003).

Conclusion:
The result of the study reveals the superiority of levocetirizine in terms of efficacy, i.e., reduction of UAS and DLQI scores. Bepotastine although slightly lower in efficacy shows better safety profile.
Profile of Dermatological Disorders among Construction Workers: A Cross-Sectional Study
Authors: Jasmine Nafina , Shetty Shricharith , Pai Sathish Ballambat 
Published: May 2023

Background:
The construction industry is a growing industry worldwide, including India, employing a large population. Construction workers perform a variety of work including mixing concrete and carrying heavy objects. Occupational contact dermatitis is a significant occupational dermatosis, cement being the most important agent and is an occupational hazard.

Objective:
The objective of this study was to estimate the prevalence of occupational skin diseases among construction workers.

Materials and Methods:
This cross-sectional study was conducted in Manipal, Karnataka, among 300 construction workers. A detailed inquiry was made on demographic parameters such as age, sex, nature of work, duration of the job, chemicals exposed to, symptoms, and use of protective devices. They were examined to note the symptoms, clinical pattern, and distribution of lesions.

Results:
The majority of the workers belonged to the age group between 20 and 29 years. The common skin disorders noticed were callosities (17.33%), traumatic injuries (10%), dermatophyte infections (8.33%), and dermatitis (5.7%) along with few other dermatoses encountered due to increased exposure to heat and due to increased wet work in workers who did not wear protective devices.

Conclusions:
There is a lack of preemployment and periodic medical examinations for construction workers. Common dermatoses seen among the construction workers were mainly due to the lack of preventive measures. Hence, it is important to raise health awareness to recognize early signs and symptoms of various dermatoses and educate regarding the use of personal protective equipment.
Conservation of Abundance
Authors: Barron Elizabeth S. 
Published: May 2023

Abstract
Mainstream biodiversity conservation continues to emphasise the rapid disappearance of charismatic megafauna. Fungi are ignored, partially because many are invisible. However, their conservation is of growing concern because their decline signals a decrease in overall biodiversity and losses in ecosystem integrity and function. Social science engagement with microbes is of growing interest because the diverse characteristics of fungal bodies create new entry points for conservation. Using data collected over three years from literature review, lab ethnography, and interviews, this paper develops two new concepts intended to operate at the intersection of these discussions. A review of the fungal conservation literature finds mainstream species conservation an ill fit for fungi. Drawing from the literature on ecosystem function and conservation biopolitics, I introduce the term ‘functional collectives’ to reframe the role of fungi in nature through a focus on fungal bodies. Acknowledging the extraordinary diversity of fungi and their relative unknowability, I further introduce the concept of ‘conservation of abundance’. A focus on abundance rather than scarcity meets the needs expressed by fungal conservationists for habitat protection and conservation based on available knowledge. Both concepts align with the biophysical realities of fungi while also answering growing calls within social conservation for conviviality and care.
Implementation Status of Airborne Infection Control Measures in Primary and Secondary Public Health Facilities, Puducherry: A Mixed-Methods Study
Authors: Talukdar Rounik , Sahu Swaroop Kumar , Rajaram Manju 
Published: May 2023

Background:
Poor ventilation in healthcare settings is a concern for airborne infections, particularly in light of the potential for coronavirus disease 2019 (COVID-19) transmission. This study aimed to assess the implementation status of airborne infection control (AIC) measures in primary and secondary public healthcare facilities (HCFs) and to explore the facilitating factors and barriers in the implementation of AIC measures.

Methods:
A mixed-methods approach was adopted, which includes a cross-sectional descriptive study using a checklist to collect data on the implementation of AIC measures in 22 primary and two secondary public HCFs in Puducherry, South India, between October 2020 and February 2021. Further, key informant interviews (KIIs) were conducted among medical officers (MOs). The qualitative data were manually analyzed, and transcripts created from handwritten notes and audio recordings were deductively evaluated.

Results:
Of the twenty-four health facilities visited, 54.2% had infection control (IC) committees. Annual IC training was held for housekeeping staff, MOs, nurses, and laboratory technicians in 23 (95.8%), 21 (87.5%), 20 (83.4%), and 14 (58.4%) facilities, respectively. Respiratory symptomatic patients were counseled on cough etiquettes in 22 (91.6%) facilities. Adequate cross-ventilation was present in outpatient departments in 16 (66.6%) institutions. N95 masks and face shields were provided in 21 (87.5%) facilities. Training through the KAYAKALP program and the presence of a separate sputum collection area were facilitators of IC, while lack of patient adherence and delays in fund release were found as barriers.

Conclusion:
Overall, the AIC measures were well-implemented, but improvements are needed in infrastructure development for patient segregation in outpatient departments and dedicated AIC training for all healthcare personnel.
Development and Validation of Clinical Schedule for Primary Care Psychiatric Nursing (CSP-N) for Primary Care Nurses
Authors: Paul James , Govindan Radhakrishnan , Manjunatha Narayana , Kumar Channaveerachari Naveen , Math Suresh Bada 
Published: May 2023

Introduction:
As per the World Health Organization’s mental health report for 2022, nearly a billion people have mental health issues, and 82% of them are in low and middle-income countries where mental health services are largely absent. For the successful integration of mental health into primary health care, proper training and education of primary care professionals are mandatory. Primary care nurses are in an excellent position to screen, identify, dual collaboration for treatment planning/referral, and follow-up of persons with mental illness (PMI), but they often lack the confidence and competence to tackle mental health problems. The study aimed to develop and validate the clinical schedule for primary care psychiatric nursing (CSP-N).

Materials and Methods:
It is conducted in two phases: the development and validation phases. An extensive literature search has been conducted, and the ten themes derived from the two-focused group discussions and three-direct one-to-one interviews and input from mental health experts were used to design the CSP-N. The CSP-N was checked for content validity by a panel of 17 experts using the item-level content validity index (I-CVI) and the scale-level content validity index (S-CVI).

Results:
The draft version 1 of the CSP-N showed high content validity for individual items (I-CVI range: 0.82 to 1.00) and high overall content validity (S-CVI = 0.95), and suggestions from the experts were incorporated. The CSP-N was developed in four modules. The single-measure two-way mixed absolute agreement ICC value was calculated (for 32 subjects) for the reliability test, and the ICC value was 0.97 with a 95% CI (0.94, 0.99).

Conclusions:
Using an iterative approach, the development and validation of the CSP-N demonstrated high I-CVI and S-CVI for screening and identification, dual collaboration for the treatment plan, referral, and follow-up of a person with mental illness by the nurses in the community.
Perioperative anesthesia challenges and outcomes of patients with Rhino-Orbito-Cerebral Mucormycosis during the second wave of COVID-19 pandemic: An observational study
Authors: Kumari Kamlesh , Rathod Darshana , Meshram Tanvi , Mohammed Sadik , Raju Sachith , Sharma Ankur , Chaudhary Bikram , Bhatia Pradeep 
Published: May 2023

Abstract

Background and Aims:
A rapid surge in rhino-orbito-cerebral mucormycosis (ROCM) cases was reported during the second wave of COVID, especially in India, needing extensive surgical debridement along with medical management. The present study was planned to observe perioperative anesthesia challenges and outcomes of patients with ROCM during the second wave of the COVID-19 pandemic. The primary objective was to observe intraoperative anesthesia challenges and the secondary objectives were to observe postoperative challenges and outcomes of patients.

Material and Methods:
This was a single-centered, bidirectional (retrospective and prospective) observational study, conducted at a tertiary care center. We enrolled 218 adult patients scheduled for surgical debridement of ROCM under general anesthesia. Demographics, COVID status, comorbid illness, intraoperative challenges (difficult airway, hemodynamic instability, blood loss), and postoperative outcome (postoperative mechanical ventilation, and mortality rate) were noted.

Results:
The majority of the patients were males (71%) and had diabetes mellitus (54%). COVID-associated mucormycosis was seen in 67% and 41% of them received steroids. Post-induction hypotension was noted in 20.6% of patients, and 14.2% had intraoperative hypotension out of which 5.5% required vasopressor support. Difficult mask ventilation and difficult intubation were reported in 7.3% and 6.4% of patients, respectively. No significant difference was found among intraoperative challenges when COVID mucormycosis was compared to non-COVID mucormycosis. Postoperative mechanical ventilation and ICU care were required in 41.3%, whereas mortality was seen in 11.5% of patients. The mortality was significantly more (P = 0.041) in patients with COVID mucormycosis (13%) compared to that with non-COVID mucormycosis (4.2%).

Conclusion:
Diabetic male patients who received steroids during COVID illness are at the highest risk of developing ROCM. Difficult airway and hemodynamic instability, are significant perioperative challenges encountered by anesthesiologists. Postoperative ICU management is crucial for decreasing postoperative morbidity and mortality.
Bosman’s Cold Stone Jug and the Genesis of the South African Prison Memoir
Authors: Roux Daniel 
Published: May 2023

This article considers Herman Charles Bosman’s memoir, Cold Stone Jug, as an early and influential prototype for the important genre of South African prison literature in the twentieth century. The memoir is attentive to the ways in which the material space of the Benthamite prison dictates social relationships and rituals, and becomes psychologically internalized. The article performs a close analysis of Bosman’s Cold Stone Jug in order to show how the distinctive chronotopes of the prison find expression in narrative form.
“Writing Home”: Storytelling as Cultural Translation in Jolyn Phillips’s ,i>Tjieng Tjang Tjerries
Authors: Marais Sue 
Published: May 2023

In this article, I discuss the mixture of English and Afrikaans that Jolyn Phillips employs in her short story collection, Tjieng Tjang Tjerries, to capture a sense of the idiom and the lived realities of the coloured fishing community of Gansbaai in the Western Cape. In addition, I locate the collection within a tradition of short story sequences by women writers from marginalized groups, and focus on the ways in which the interlinked narratives it contains emphasize the notion that personal identity, community and place are inextricably connected. Ultimately, I maintain that, despite the bleak socioeconomic circumstances, alcoholism and abuse that Phillips depicts in many of the stories, the dominant tone of the collection is not one of disenchantment with contemporary South African realities. This is because of the gentleness and affection with which Phillips treats her subjects, and the gleeful brand of raunchily direct humour she injects into her stories.
Embalmment, islamic legality and medicolegal concept: A Review
Authors: Yahaya G. , Hassan A.H. , Aliyu I.A. 
Published: May 2023

Embalmment an art of science of temporarily preserving human remains to forestall decomposition and make it suitable for at funeral. It also assists in preserving humans for studying medical courses. It causes tissues to harden by coagulating tissue proteins that gets fixed and hardened. The aim of the study is to understand embalmment and different views from religion and socio-cultural perspectives Research publication articles from Pubmed, Medline and many others were searched using google search engine. Over seventy journals of repute were obtained out of which more than forty gives reputable result information of socio-cultural and medico legal effects of embalmment. Embalming human cadaver is attributed to scio-cultural effects and religious views in different part of the world.
The prevalence and density of asymptomatic plasmodium infections among children in a rural community of South- Western Nigeria.
Authors: Oduwole Olabisi A. , Ale Toluwalase , Bello Segun , Shoyinka Samuel , Okebe Joseph 
Published: May 2023

Asymptomatic malaria is highly prevalent in endem ic areas of Africa and it is a new challenge for the malaria elimination agenda. In recent years, the number of hospitalizations due to malaria cases in sub-Saharan Africa has steadily decreased. However, there are indications that this positive trend could suffer a setback due to asymptomatic malaria cases, which may serve as reservoir of infections for vulnerable populations. This cross-sectional study examined the prevalence of asymptomatic malaria in school-aged children living in a rural community in South- West, Nigeria. The study was conducted from August to September 2020, involving 300 randomly selected school children. Histidine rich protein II rapid diagnostic test kits (HRP2) were used to screen participants for malaria. All blood samples were further examined microscopically using 3% Giemsa-stained blood smears for confirmation, speciation, and parasites. The anaemia status of the children was quantification of malaria determined by measuring the haematocrit. Statistical analysis of the data was done using the chi-square test, student t-test, Mann Whitney U test and Kruskal-Wallis rank sum tests to determine the association between variables and the difference in mean/median with a significance level p≤ 0.05. The results showed a high prevalence of asymptomatic malaria of 41% by microscopy. The prevalence of asymptomatic malaria was statistically significantly higher among children aged 6 to 11 years (52%), compared to children >12years (37%), and < 5years old (13%), (p=0.00001). Plasmodium falciparum was responsible for 96% of the infection while the remaining 4% had multiple infections with Plasmodium falciparum and Plasmodium ovale. This study confirms that the prevalence of asymptomatic cases of malaria among children in malaria endemic areas is high and they will benefit from malaria chemoprophylaxis.
Selected Biomarkers of Coagulation Disturbance in Newly Diagnosed Breast Cancer Patients
Authors: Udosen Joseph E. , Akwiwu Euphoria C. , Njar Valerie E. , Akpotuzor David U. , Abunimye Dennis , Akpotuzor Josephine O. 
Published: May 2023

Coagulation disturbance can be quite detrimental to health, whether as a primary disorder or secondary to other medical conditions. The risk of thrombosis has been previously reported in breast cancer. This case- control study purposively enrolled 50 newly diagnosed female breast cancer patients. Quick's One-stage method was used for prothrombin time (PT) and activated partial thromboplastin time (APTT) tests, while fibrin plate lysis method was used for euglobulin lysis time (ELT) assessment. Data analysis was carried out on statistical package for social sciences (SPSS) version 20.0. A p-value ≤ 0.05 was considered significant. Mean values of PT, APTT and ELT of newly diagnosed breast cancer patients were compared to values from control subjects. The ELT was significantly prolonged in the breast cancer patients compared to that of controls (p = 0.001). These measured parameters were further compared within the breast cancer group on the basis of hours of immobility per day into three categories (<3 hours, 3-6 hours and >6 hours). Subjects with more than 6 hours of immobility Subjects with more than 6 hours of immobility per day had significantly prolonged ELT compared to those with lesser hours of immobility. This study concludes that fibrinolytic challenge exists in breast cancer prior to commencement of treatment particularly among patients with increasing immobility.
Finiteness for self-dual classes in integral variations of Hodge structure
Authors: Bakker Benjamin , Grimm Thomas W. , Schnell Christian , Tsimerman Jacob 
Published: May 2023

We generalize the finiteness theorem for the locus of Hodge classes with fixed self-intersection number, due to Cattani, Deligne, and Kaplan, from Hodge classes to self-dual classes. The proof uses the definability of period mappings in the o-minimal structure $\mathbb{R}_{\mathrm{an},\exp}$.Comment: v3: final version
Ефективність обробляння насіння сої культурної Glycine max (L.) Merr. біопрепаратами у підвищенні її продуктивності
Authors: Димитров Сергій , Саблук Василь 
Published: May 2023

Мета. Встановлення ефективності обробляння насіння сої біопрепаратами у підвищенні її продуктивності. Методи. Польові, лабораторні та статистичні. Результати. За використання біопрепаратів для обробляння насіння сої перед сівбою отримано позитивні результати щодо їх впливу на ріст та розвиток рослин і формування врожаю цієї культури. Зокрема, площа листків у варіантах з грибами Glomus VS і Trichoderma harzianum RIFAI. (препарат Мікофренд) та Tuber melanosporum VITTAD. (препарат Міковітал) і бактеріями Bacillus subtilis Cohn. (препарат Флоробацилін) за обліків на 30, 60 і 90 днів органогенезу була на 24,4–69,8 % більшою порівняно з контролем. Так само маса листків та маса кореневої системи переважали показники контролю відповідно на 8,3–40,5 % і 9,3–59,8 %. Разом з тим, у варіантах з мікоризоутворювальними грибами підвищувалась вологоутримуюча здатність ґрунту на 11,4–14,8 % та його структурно-агрегатний стан – частка грудочок розміром – 0,25–10,0 мм була більшою за контроль на 0,9–5,2 %. Відповідно підвищувалась порівняно з контролем урожайність насіння сої культурної на 0,14–0,89 т/га. Особливо високу ефективність у покращені росту та розвитку рослин сої отримано за використання біопрепарату Мікофренд. Зокрема, у варіантах з ним наростання площі листкової поверхні було більшим за контроль у 40,9–89,8 % тоді як з іншими препаратами (Міковітал і Флоробацилін) ці показники становили 24,5–47,9 %, що на 12,8–16,4 % менше. Така ж різниця проявляється і в інших елементах росту та розвитку рослин таких зокрема як маса кореневої системи, висота рослин, фотосинтетичний потенціал і продуктивність фотосинтезу тощо. Висновки. Використання мікоризоутворювальних грибів Glomus VS і Trichoderma harzianum RIFAI. (препарат Мікофренд) і Tuber melanosporum VITTAD. (препарат Міковітал), а також азотфіксуючих бактерій Bacillus subtilis Cohn. (препарат Флоробацилін) за допосівного обробляння ними насіння сприяють покращенню росту та розвитку рослин сої культурної та підвищенню їхньої продуктивності.
Просторічно-жаргонна лексика як складник мовного портрета сучасних студентів
Authors: Романчук Світлана 
Published: May 2023

У запропонованому науковому доробку Світлана Романчук розглядає мовний портрет сучасних студентів. Під мовним портретом вона пропонує розуміти втілену у мові комунікативну (мовну) особистість, що є представником певної соціальної спільності (середовища). Лексикон сучасної молодої людини поєднує у собі різноманітні елементи. Крім загальновживаних слів, до нього входять жаргони, знижена і просторічна лексика, іншомовні слова (найчастіше англіцизми, що виступають у різних модифікаціях і скороченнях), обсценні вкраплення, інвективи, емотивно-експресивні характеристики, слова-паразити, дисфемізи загалом створюють особливу (занижену) стилістичну забарвленість мови. Значну увагу авторка звертає на жаргони, які вважаються специфічною формою мовної реалізації комунікативної особистості. У них відображаються соціально-історичні умови життя молодіжного колективу, рівень його культури, моральні установки, уявлення про життєві цінності, орієнтири, система оцінок, подій, фактів, життєвого укладу та багато інших. Світлана Романчук аналізує структуру молодіжного жаргону, характеризує його ознаки. Цінним для наукового опису є визначення рівня використання жаргонної лексики в різних засобах інформаційних технологій, зокрема в Інтернеті та під час спілкування в чатах по мобільному телефону. Мовний портрет сучасної молодої людини (особливо студента) не можна уявити без прецедентних текстів – цитат з відомих літературних творів, фразеологізмів, крилатих виразів, прислів'їв та приказок, гасел, фраз з популярних пісень та кінофільмів, рекламних роликів та ін. У статті йдеться, що використання прецедентних текстів робить мовлення молодих людей яскравим, нетривіальним, розкутим, дотепним, сприяє вдосконаленню комунікативної та міжкультурної компетенції. Також у науковому дослідженні проаналізовано дисфемізми, слова-паразити, арготизми, обсценну та кримінальну лексика, елементи блатної мови і навіть лайку, які є доволі поширеними не тільки в моодіжному середовищі, але й в масмедійному просторі. Підсумовано, що існує об'єктивна суперечність між вимогами суспільства та недостатньою комунікативною компетентністю майбутніх фахівців, що не дозволяє їм успішно протистояти просторічно-жаргонній стихії та іншим негативним процесам розвитку сучасної української мови та формуванню високої мовної культури сучасних студентів.