bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Balian–Low type theorem for Gabor Riesz sequences of arbitrary density
Authors: Caragea Andrei , Lee Dae Gwan , Philipp Friedrich , Voigtlaender Felix 
Published: January 2023

AbstractGabor systems are used in fields ranging from audio processing to digital communication. Such a Gabor system $$(g,\varLambda )$$

(
g
,
Λ
)

consists of all time-frequency shifts $$\pi (\lambda ) g$$

π
(
λ
)
g

of a window function $$g \in L^2({\mathbb {R}})$$

g
∈

L
2

(
R
)

along a lattice $$\varLambda \subset {\mathbb {R}}^2$$

Λ
⊂

R

2

. We focus on Gabor systems that are also Riesz sequences, meaning that one can stably reconstruct the coefficients $$c = (c_\lambda )_{\lambda \in \varLambda }$$

c
=

(

c
λ

)

λ
∈
Λ

from the function $$\sum _{\lambda \in \varLambda } c_\lambda \, \pi (\lambda ) g$$

∑

λ
∈
Λ

c
λ

π

(
λ
)

g

. In digital communication, a function of this form is used to transmit the digital sequence c. It is desirable for g to be well localized in time and frequency, since the transmitted signal will then be almost compactly supported in time and frequency if the sequence c has finite support. In this paper, we study what additional structural properties the signal space $$\mathcal {G}(g,\varLambda )$$

G
(
g
,
Λ
)

, i.e., the span of the Gabor system, satisfies in addition to being a closed subspace of $$L^2({\mathbb {R}})$$

L
2

(
R
)

. The most well-known result in this direction—the Balian–Low theorem—states that if g is well localized in time and frequency and if $$(g,\varLambda )$$

(
g
,
Λ
)

is a Riesz sequence, then $$\mathcal {G}(g,\varLambda )$$

G
(
g
,
Λ
)

is necessarily a proper subspace of $$L^2({\mathbb {R}})$$

L
2

(
R
)

. We prove a generalization of this result related to the invariance of $$\mathcal {G}(g,\varLambda )$$

G
(
g
,
Λ
)

under time-frequency shifts. Precisely, we show that if $$(g,\varLambda )$$

(
g
,
Λ
)

is a Riesz sequence with g being well localized in time and frequency (precisely, g should belong to the so-called Feichtinger algebra), then $$\pi (\mu ) \mathcal {G}(g,\varLambda ) \subset \mathcal {G}(g,\varLambda )$$

π
(
μ
)
G
(
g
,
Λ
)
⊂
G
(
g
,
Λ
)

holds if and only if $$\mu \in \varLambda $$

μ
∈
Λ

. For lattices of rational density, this was already known, with the proof based on Zak transform techniques. These methods do not generalize to arbitrary lattices, however. Instead, our proof for lattices of irrational density relies on combining methods from time-frequency analysis with properties of a special $$C^*$$

C
∗

-algebra, the so-called irrational rotation algebra.
Dispersive magnetic solid-phase extraction for capsaicinoid compounds in human serum using LC-HRMS: targeted and non-targeted approaches
Authors: Rodríguez-Palazón María Consolación , Arroyo-Manzanares Natalia , Viñas Pilar , López-García Ignacio , Hernández-Córdoba Manuel , Campillo Natalia 
Published: January 2023

AbstractA new analytical method based on the use of dispersive magnetic solid-phase extraction (DMSPE) is described for the preconcentration of capsaicin (CAP), dihydrocapsaicin (DCAP), and N-vanillylnonanamide (PCAP) from human serum samples. The influence of several experimental factors affecting the adsorption (nature and amount of magnetic material, adsorption time, and pH) and desorption (nature of solvent, its volume and desorption time) steps was studied. Among seven different nanomaterials studied, the best results were obtained using magnetic multiwalled carbon nanotubes, which were characterized by means of spectrometry- and microscopy-based techniques. Analyses were performed by ultra-high-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry using electrospray ionization in positive mode (UHPLC-ESI-Q-TOF-MS). The developed method was validated by obtaining several parameters, including linearity (0.3–300 μg L−1 range), and limits of detection which were 0.1, 0.15, and 0.17 μg L−1 for CAP, DCAP, and PCAP, respectively. The repeatability of the method, expressed as relative standard deviation (RSD, n = 7), varied from 3.4 to 11%. The serum samples were also studied through a non-targeted approach in a search for capsaicinoid metabolites and related compounds. With this objective, the fragmentation pathway of this family of compounds was initially studied and a strategy was established for the identification of novel or less studied capsaicinoid-derived compounds.
Graphical abstract
Revealing charge heterogeneity of stressed trastuzumab at the subunit level
Authors: Spanov Baubek , Baartmans Bas , Olaleye Oladapo , Nicolardi Simone , Govorukhina Natalia , Wuhrer Manfred , van de Merbel Nico C. , Bischoff Rainer 
Published: January 2023

AbstractTrastuzumab is known to be heterogeneous in terms of charge. Stressing trastuzumab under physiological conditions (pH 7.4 and 37 °C) increases charge heterogeneity further. Separation of charge variants of stressed trastuzumab at the intact protein level is challenging due to increasing complexity making it difficult to obtain pure charge variants for further characterization. Here we report an approach for revealing charge heterogeneity of stressed trastuzumab at the subunit level by pH gradient cation-exchange chromatography. Trastuzumab subunits were generated after limited proteolytic cleavage with papain, IdeS, and GingisKHAN®. The basic pI of Fab and F(ab)2 fragments allowed to use the same pH gradient for intact protein and subunit level analysis. Baseline separation of Fab subunits was obtained after GingisKHAN® and papain digestion and the corresponding modifications were determined by LC–MS/MS peptide mapping and middle-down MALDI-ISD FT-ICR MS. The described approach allows a comprehensive charge variant analysis of therapeutic antibodies that have two or more modification sites in the Fab region.
Paediatric Ureteroscopy (P-URS) reporting checklist: a new tool to aid studies report the essential items on paediatric ureteroscopy for stone disease
Authors: Juliebø-Jones Patrick , Ulvik Øyvind , Beisland Christian , Somani Bhaskar K. 
Published: January 2023

AbstractThe burden of urolithiasis in children is increasing and this is mirrored by the number of surgical interventions in the form of ureteroscopy (URS). There exist many challenges in performing this surgery for this special patient group as well as a lack of consensus on technique. There is also large variation in how results are described and reported. There exists therefore, a need to improve and standardise the core outcomes, which are reported. To this end, we developed a new checklist to aid studies report the essential items on paediatric URS for stone disease. The Paediatric Ureteroscopy (P-URS) reporting checklist comprises four main sections (study details, pre-operative, operative and post-operative) and a total of 20 items. The tool covers a range of important elements, such as pre-stenting, complications, follow-up, stone-free rate, concomitant medical expulsive therapy and imaging, which are often lacking in studies. The checklist provides a summary of essential items that authors can use as a reference to improve general standards of reporting paediatric URS studies and increase the body of knowledge shared accordingly.
GRF–GIF chimeric proteins enhance in vitro regeneration and Agrobacterium-mediated transformation efficiencies of lettuce (Lactuca spp.)
Authors: Bull Tawni , Debernardi Juan , Reeves Megan , Hill Theresa , Bertier Lien , Van Deynze Allen , Michelmore Richard 
Published: January 2023

Key message
GRF–GIF chimeric proteins from multiple source species enhance in vitro regeneration in both wild and cultivated lettuce. In addition, they enhance regeneration in multiple types of lettuce including butterheads, romaines, and crispheads.

Abstract
The ability of plants to regenerate in vitro has been exploited for use in tissue culture systems for plant propagation, plant transformation, and genome editing. The success of in vitro regeneration is often genotype dependent and continues to be a bottleneck for Agrobacterium-mediated transformation and its deployment for improvement of some crop species. Manipulation of transcription factors that play key roles in plant development such as BABY BOOM, WUSCHEL, and GROWTH-REGULATING FACTORs (GRFs) has improved regeneration and transformation efficiencies in several plant species. Here, we compare the efficacy of GRF–GIF gene fusions from multiple species to boost regeneration efficiency and shooting frequency in four genotypes of wild and cultivated lettuce (Lactuca spp. L.). In addition, we show that GRF–GIFs with mutated miRNA 396 binding sites increase regeneration efficiency and shooting frequency when compared to controls. We also present a co-transformation strategy for increased transformation efficiency and recovery of transgenic plants harboring a gene of interest. This strategy will enhance the recovery of transgenic plants of other lettuce genotypes and likely other crops in the Compositae family.
Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS
Authors: Agrafiotis Andreas , Dizerens Raphael , Vincenti Ilena , Wagner Ingrid , Kuhn Raphael , Shlesinger Danielle , Manero-Carranza Marcos , Cotet Tudor-Stefan , Hong Kai-Lin , Page Nicolas , Fonta Nicolas , Shammas Ghazal , Mariotte Alexandre , Piccinno Margot , Kreutzfeldt Mario , Gruntz Benedikt , Ehling Roy , Genovese Alessandro , Pedrioli Alessandro , Dounas Andreas , Franzenburg Sören , Tumani Hayrettin , Kümpfel Tania , Kavaka Vladyslav , Gerdes Lisa Ann , Dornmair Klaus , Beltrán Eduardo , Oxenius Annette , Reddy Sai T. , Merkler Doron , Yermanos Alexander 
Published: January 2023

AbstractB cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such conditions, B cells may enter the CNS parenchyma and contribute to local tissue destruction. It remains unexplored, however, how infection and autoimmunity drive transcriptional phenotypes, repertoire features, and antibody functionality. Here, we profiled B cells from the CNS of murine models of intracranial (i.c.) viral infections and autoimmunity. We identified a population of clonally expanded, antibody-secreting cells (ASCs) that had undergone class-switch recombination and extensive somatic hypermutation following i.c. infection with attenuated lymphocytic choriomeningitis virus (rLCMV). Recombinant expression and characterisation of these antibodies revealed specificity to viral antigens (LCMV glycoprotein GP), correlating with ASC persistence in the brain weeks after resolved infection. Furthermore, these virus-specific ASCs upregulated proliferation and expansion programs in response to the conditional and transient induction of the LCMV GP as a neo-self antigen by astrocytes. This class-switched, clonally expanded, and mutated population persisted and was even more pronounced when peripheral B cells were depleted prior to autoantigen induction in the CNS. In contrast, the most expanded B cell clones in mice with persistent expression of LCMV GP in the CNS did not exhibit neo-self antigen specificity, potentially a consequence of local tolerance induction. Finally, a comparable population of clonally expanded, class-switched, and proliferating ASCs was detected in the cerebrospinal fluid of relapsing multiple sclerosis (RMS) patients. Taken together, our findings support the existence of B cells that populate the CNS and are capable of responding to locally encountered autoantigens.
Appendiceal goblet cell carcinoma has marginal advantages from perioperative chemotherapy: a population-based study with an entropy balancing analysis
Authors: Ricci Claudio , Campana Davide , Ingaldi Carlo , Lamberti Giuseppe , Alberici Laura , Tateo Valentina , Castagna Giovanni , Ricco Gianluca , Calderaro Fulvio , Malvi Deborah , Rosini Francesca , Casadei Riccardo 
Published: January 2023

Abstract
Purpose
The aim is to clarify the use of perioperative chemotherapy in resectable goblet cell carcinoma (GCC).

Methods
A retrospective study was carried out based on the Surveillance, Epidemiology, and End Results study. The population was divided: into patients who received only radical surgery (group A) and those who received radical surgery plus chemotherapy (group B). An entropy balancing was carried out to correct the imbalance between the two groups. Two models were generated. Model 1 contained only high-risk patients: group B and a “virtual” group A with similar characteristics. Model 2 included only low-risk patients: group A and “virtual” group B with identical attributes. The efficacy of entropy balancing was evaluated with the d value. The overall survival was compared and reported with Hazard Ratio (HR) within a confidence interval of 95% (95 CI).

Results
The groups A and B were imbalanced for tumor size (d = 0.392), T (d = 1.128), N (d = 1.340), M (d = 1.456), mean number of positive lymph nodes (d = 0.907), and LNR (d = 0.889). Before the balancing, the risk of death was higher in group B than in A (4.3; 2.5 to 7.4). After reweighting, all large differences were eliminated (d < 0.200). In high-risk patients, the risk of death was higher in patients who underwent surgery alone than those who received perioperative chemotherapy (HR 0.5; 0.2 to 1.3) without statistical significance (p = 0.187). In low-risk patients, the risk of death was similar (HR 1.1; 0.3 to 3.3).

Conclusion
Perioperative chemotherapy could provide some marginal advantages to high-risk patients.
Fast computation of distance-generalized cores using sampling
Authors: Tatti Nikolaj 
Published: January 2023

AbstractCore decomposition is a classic technique for discovering densely connected regions in a graph with large range of applications. Formally, a k-core is a maximal subgraph where each vertex has at least k neighbors. A natural extension of a k-core is a (k, h)-core, where each node must have at least k nodes that can be reached with a path of length h. The downside in using (k, h)-core decomposition is the significant increase in the computational complexity: whereas the standard core decomposition can be done in $${{\mathcal {O}}}{\left( m\right) }$$

O

m

time, the generalization can require $${{\mathcal {O}}}{\left( n^2m\right) }$$

O

n
2

m

time, where n and m are the number of nodes and edges in the given graph. In this paper, we propose a randomized algorithm that produces an $$\epsilon $$
ϵ
-approximation of (k, h) core decomposition with a probability of $$1 - \delta $$

1
-
δ

in $${{\mathcal {O}}}{\left( \epsilon ^{-2} hm (\log ^2 n - \log \delta )\right) }$$

O

ϵ

-
2

h
m

(

log
2

n
-
log
δ
)

time. The approximation is based on sampling the neighborhoods of nodes, and we use Chernoff bound to prove the approximation guarantee. We also study distance-generalized dense subgraphs, show that the problem is NP-hard, provide an algorithm for discovering such graphs with approximate core decompositions, and provide theoretical guarantees for the quality of the discovered subgraphs. We demonstrate empirically that approximating the decomposition complements the exact computation: computing the approximation is significantly faster than computing the exact solution for the networks where computing the exact solution is slow.
Developing Test Methods for Compression after Lightning Strikes
Authors: Xu Xiaodong , Millen Scott L. J. , Lee Juhyeong , Abdelal Gasser , Mitchard Daniel , Wisnom Michael R. , Murphy Adrian 
Published: January 2023

AbstractResearch into residual strength after lightning strike is increasing within the literature. However, standard test methods for measuring residual compressive strength after lightning strikes do not exist. For the first time, a systematic experimental study is undertaken to evaluate modifications necessary to standard Compression After Impact (CAI) specimen geometry and test jig design to induce specimen failure at the lightning damage region. Four laboratory generated lightning strike currents with peak amplitudes ranging from 25 to 100 kA have been studied. Test set-up modifications were made considering the scale of the lightning damage and its potential proximity to specimen edges. Specimen geometry and anti-buckling guides were adjusted for each peak current to induce specimen failure at the lightning damage. The Compression After Lightning (CAL) strength was 28% lower than the pristine CAI strength even at a relatively low peak current of 25 kA. This study shows that the standard CAI test setup has the potential for CAL application, however, careful modifications are required depending on the peak amplitude of the applied lightning current waveform.
“Greedy” demand adjustment in cooperative games
Authors: Montero Maria , Possajennikov Alex 
Published: January 2023

AbstractThis paper studies a simple process of demand adjustment in cooperative games. In the process, a randomly chosen player makes the highest possible demand subject to the demands of other coalition members being satisfied. This process converges to the aspiration set; in convex games, this implies convergence to the core. We further introduce perturbations into the process, where players sometimes make a higher demand than feasible. These perturbations make the set of separating aspirations, i.e., demand vectors in which no player is indispensable in order for other players to achieve their demands, the one most resistant to mutations. We fully analyze this process for 3-player games. We further look at weighted majority games with two types of players. In these games, if the coalition of all small players is winning, the process converges to the unique separating aspiration; otherwise, there are many separating aspirations and the process reaches a neighbourhood of a separating aspiration.
Religiosity and Charitable Giving on Investors’ Trading Behaviour in the Indonesian Islamic Stock Market: Islamic vs Market Logic
Authors: Asutay Mehmet , Aziz Primandanu Febriyan , Indrastomo Banjaran S. , Karbhari Yusuf 
Published: January 2023

AbstractThis study examines retail investors’ trading behaviour and its determinants in the Indonesian Shari’ah stock market by mainly focusing on the religious practice-related factors in the form of sadaqah or charitable giving on individual investors’ trading behaviour. Contextually, the Islamic moral economy (IME) assumes a direct relationship between religiosity and sadaqah giving due to the falah (salvation) oriented individual objective function, which can be reached through doing ihsan (beneficence for equilibrium). The findings based on a questionnaire survey distributed to individual investors on Shari’ah Online Trading System (SOTS) delineate that religiosity, accounting information, neutral information, personal financial needs, and the sadaqah feature have significantly affected investors’ trading behaviour in which the sadaqah feature is positively correlated, while religiosity factors are negatively correlated. Thus, despite the theoretical expectation through IME, this study evidences that Islamic logic is not the main determining factor, as market logic related factors seem to be more dominant in the behaviour of investors in the Indonesian capital market.
X-chromosome inactivation patterns depend on age and tissue but not conception method in humans
Authors: Juchniewicz Patrycja , Kloska Anna , Portalska Karolina , Jakóbkiewicz-Banecka Joanna , Węgrzyn Grzegorz , Liss Joanna , Głodek Piotr , Tukaj Stefan , Piotrowska Ewa 
Published: January 2023

AbstractFemale somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes, randomly silencing the maternal or paternal X chromosome in each cell of 46,XX females. Skewed XCI toward one parental X has been observed in association with ageing and in some female carriers of X-linked diseases. To address the problem of non-random XCI, we quantified the XCI skew in different biological samples of naturally conceived females of different age groups and girls conceived after in vitro fertilization (IVF). Generally, XCI skew differed between saliva, blood, and buccal swabs, while saliva and blood had the most similar XCI patterns in individual females. XCI skew increased with age in saliva, but not in other tissues. We showed no significant differences in the XCI patterns in tissues of naturally conceived and IVF females. The gene expression profile of the placenta and umbilical cord blood was determined depending on the XCI pattern. The increased XCI skewing in the placental tissue was associated with the differential expression of several genes out of 40 considered herein. Notably, skewed XCI patterns (> 80:20) were identified with significantly increased expression levels of four genes: CD44, KDM6A, PHLDA2, and ZRSR2. The differences in gene expression patterns between samples with random and non-random XCI may shed new light on factors contributing to the XCI pattern outcome and indicate new paths in future research on the phenomenon of XCI skewing.
Age-Related Variations of Genetic and Environmental Contributions to the Covariation of Fear, Distress and Externalizing Symptoms: A Twin Study in Childhood and Adolescence
Authors: De Francesco Stefano , Scaini Simona , Alessandri Guido , Medda Emanuela , Camoni Laura , Stazi Maria Antonietta , Fagnani Corrado 
Published: January 2023

AbstractThe frequency with which Internalizing and Externalizing symptoms co-occur suggests that, behind both domains, there may be a common susceptibility represented by a general psychopathology factor. However, it’s still unclear whether this common susceptibility is affected by age-related variations. Internalizing (i.e., Fear and Distress) and Externalizing symptoms were evaluated in 803 twin pairs from the population-based Italian Twin Registry. Model-fitting analysis was performed separately in the 6–14 and 15–18 age groups to estimate genetic and environmental contributions to the covariance among symptoms. For the 6–14 group, a multivariate Cholesky model best fitted the data, while, for the 15–18 group, the best fit was provided by a Common Pathway model in which nearly 50% of total variance of each trait was mediated by common genetic factors. Our findings support a common susceptibility behind Internalizing and Externalizing symptoms, mainly genetic in origin, that becomes more evident at the beginning of puberty.
Social Media Platforms and User Engagement: A Multi-Platform Study on One-way Firm Sustainability Communication
Authors: Jha Ashish Kumar , Verma Nishant Kumar 
Published: January 2023

AbstractThere have been multiple research studies in recent days that have analyzed the growing role of social media in firms’ communication strategy as well as the role of social media in shaping a firm’s reputation. However, most of these studies focus on one of the multiple social media platforms that firms use. In this study, we argue that there are nuances in firms’ social media communication strategies depending on the platforms. Given the rising importance of sustainability, we focus on firms’ sustainability-related communication. We analyze the impact of firms’ one-way sustainability communication over Twitter and Facebook on the respective platforms’ user engagement. The engagement has been computed as likes and shares (likes and retweets) over the firm generated one-way sustainability communication-related posts. Using a panel dataset of a 3-year period for S&P 500 firms having active social media profiles on both platforms, we demonstrate the difference in the firms’ sustainability communication on the two platforms. We also find evidence that users on both platforms have different preferences, such as messaging from firms. Using a differential metric in our analysis helps us counter the firm-level fixed effects. We find evidence suggesting that firms would do well by having different strategies for different platforms. Firms would benefit by focusing on sustainability relevant and bite-sized content on Twitter, but more positive and engaging content on Facebook.