bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resource Utilization and Cost Implications of Container Live Migration in Clouds: An Approach Performed on Amazon Web Services (AWS)
Authors: BOUAOUDA Amine , AFDEL Karim , ABOUNACER Rachida 
Published: September 2023

Abstract
Containerization has emerged as a popular technology for deploying applications in cloud environments due to its lightweight and portable nature. As containers become increasingly prevalent, the need for efficient live migration techniques to support workload balancing, fault tolerance, and resource optimization has become evident. In this study, we investigate the impact and cost of container live migration in the context of cloud computing. Leveraging the capabilities of Amazon Web Services (AWS), we establish an experimental approach by using different technologies of AWS like Amazon Elastic Compute Cloud (EC2), Amazon Elastic Kubernetes Service (EKS), and AWS CloudWatch, to facilitate live migration of containers and tracking its cost implications. Our findings provide valuable insights into the effectiveness and efficiency of container live migration in cloud environments, paving the way for informed decision-making and optimization strategies for containerized workloads in production settings.
Assessment of spatio-temporal pattern of water hyacinth (Eichhornia crassipes) dynamics and its nitrogen and phosphorus content of lake koka, south east of Addis Ababa, Ethiopia
Authors: Chane Habetamu , Kumssa Tewodros 
Published: September 2023

Abstract
Background
The water hyacinth (Eichhornia crassipes)is often regarded as the world's most notorious invasive species. In Southern eastern Ethiopia, Lake Koka has serious problems related to the alien water hyacinth invasive weed. This study aimed to examine the spatial-temporal pattern of water hyacinth, and its dynamic with seasonal variability and the nutrient (Nitrogen and phosphorus) content of Lake Koka. The area of water hyacinth and surface area of the Lake were mapped using Landsat 7 ETM + and Landsat 8OLI image data from the years 2013, 2017, and 2021 and Sentinel-2 MS I image data of 2017–2021. The amount Total Nitrogen was determined by TNT Persulfate Digestion Method and Total Phosphorus by Molybdovanadate Method.
Result: The annual coverage areas of water hyacinth increased by 328.89%. from 45.74.ha in 2013 to 2123 ha in 2021 over the last nine years. The annual maximum lake surface area was 164.63 km2 occurred in2017 and the minimum was 77.38 in 2021 km2. Seasonal spatial-temporal dynamics of water hyacinth in Lake Koka exhibit a periodic cyclical pattern, The mean percentage seasonal land uses of Water Hyacinth are the maximum on Spring 2.99%, followed by Summer 2.10%, then 1.25% in winter and the list is on the Autumn 0.57%. Total Nitrogen was average ranging from 5.6.-16.5mg/L However, the concentration varied from site to site with the highest concentration site of draining the wet season average value of 13–19 mg/L. Total Phosphorus was average ranged from < .001-0.85mg/L. However, the concentration varied from site to site with the highest concentration site of draining the wet season with average value of 1 -1.3 mg/L.
Conclusion: In general, the significantly increasing spatial coverage of water hyacinth on lake Koka in the last 9 years and impearled with water quality degradation, however, the management and control almost nil wards to the weed infestation. Therefore, a holistic approach, effective and sustainable management strategy, and action must be implemented to stop the spread of water hyacinth on Lake Koka.
A theoretical study on toluene oxidization by OH radical
Authors: Mao Yumin , Yang Lijuan , Liu Siqi , Song Yunchang , Luo Mengchao , Guo Yongxue 
Published: September 2023

Abstract
Toluene, a critical constituent of Volatile Organic Compounds (VOCs), poses significant adverse effects on human health and the environment. The hydroxyl radical (•OH) is an efficient reactive species that actually carries out the oxidation in Advanced Oxidation Processes (AOPs) for VOCs removal. In this study, we employed computational quantum mechanical methods and experiments to systematically investigate the process of toluene degradation by •OH. Theoretical studies suggest that •OH may oxidize toluene via three possible reaction pathways: formation of phenol after hydrogen abstraction of the phenyl ring and capture of •OH, addition of •OH to the phenyl ring followed by ring-opening reaction, and side-chain oxidation of toluene to benzoic acid followed by addition of •OH and ring-opening reaction. The latter two oxidation pathways enable toluene's ring-opening via •OH addition, which significantly reduces the energy barrier of the ring-opening process. Therefore, we speculate toluene could be efficiently degraded via these two pathways. The computational results align well with the experimental outcomes derived from GC-MS characterization of intermediates in the post-reaction solution. Experimental results indicate that the predominant free radical species in the UV-H2O2 system are •OH and 1O2, with •OH being the principal active species in the degradation of toluene.
Estimation of Peptic ulcer risk through Mendelian randomization analyses using genetically predicted circulating levels of cytokines
Authors: Liu Xianqiang , Li Dingchang , Gao Wenxing , zhao Wen , Chen Peng , Liu Hao , Zhao Yingjie , Dong Guanglong 
Published: September 2023

Abstract
Background
The association of some inflammatory cytokines such as CRP, IL-1, and TNFα with peptic ulcer has been reported. To investigate the causal relationship between 41 inflammatory cytokines and peptic ulcers, a Mendelian randomization (MR) analysis was conducted.
Methods:
Two-sample MR was conducted using data available on genetic variation in peptic ulcer from a comprehensive genome-wide association study (GWAS) that included 130 individuals of European ancestry with peptic ulcer and 189,695 control participants. Additionally, data on inflammatory cytokines were obtained from a pooled GWAS comprising 8,293 healthy individuals. The causal relationship between exposure and outcome was explored primarily using an inverse variance weighting approach. Furthermore, several sensitivity analysis techniques, such as MR-Egger, weighted median, simple model, weighted model, and MR-PRESSO, were employed to strengthen the robustness of the final findings.
Results:
The acquired data implied that platelet-derived growth factor-BB (PDGF_BB), stromal cell-derived factor-1α (SDF_1A), and macrophage inflammatory protein 1-a (MIP_1A) may be associated with the risk of peptic ulcer ([ORIVW: 4.148. 95% CI: 1.74-9. 87; P = .0013], MIP_1A [ORIVW: 0.199; 95% CI: 0.067–0.593; P = .0037] SDF_1A [ORIVW: 0.318,0.117–0.866; P = .0249]. Furthermore, the absence of inflammatory factors is considered a consequence of PUD.
Conclusion:
The present study suggests that PDGF_BB, SDF_1A, and MIP_1A may be factors associated with PUD.
Circadian clock-related genome-wide Mendelian randomization identifies putatively genes for ulcerative colitis and its comorbidity
Authors: Lu Yue , Wu Yuan , Li Yiting , Li Zuming , Chen Xueru , Wu Siyi , Li Jiqiang , Chen Jiankun , Feng Yan 
Published: September 2023

Abstract
Background Circadian rhythm is crucial to the function of the immune system. Disorders of the circadian rhythm can lead to inflammatory diseases such as UC. This Mendelian Randomization (MR) analysis applies genetic tools to represent the aggregated statistical results of exposure to circadian rhythm disorders and UC and its comorbidities, allowing for causal inferences.
Methods Summary statistics were conducted on UC and its comorbidities, protein expression quantitative trait loci, DNA methylation and gene expression in individuals of European ancestry (pQTL, mQTL, and eQTL, respectively). Genetic variants located within or near 120 circadian clock-related genes and closely related to circadian rhythm disorders were selected as instrumental variables, and the causal relationships with UC and its comorbidities were estimated through aggregated summary data-based MR (SMR) analysis.
Findings Through preliminary SMR analysis, we found a potential causal relationship between circadian clock-related genes and UC and its comorbidities. Our study identified strong evidence of positive correlation of four overlapping genes (CSNK1E, OPRL1, PIWIL2, and RORC) between MWAS and TWAS were identified in UC, three overlapping genes (OPRL1, CHRNB2, and FBXL17) in UC with PSC, and two overlapping genes (ARNTL and USP7) in UC with arthropathy.
Interpretations This SMR study demonstrates the causal effect of circadian rhythm disorders in UC and its comorbidities. In addition, our research identified candidate genes which could serve as potential drug targets.
AAR:Attention Remodulation for Weakly Supervised Semantic Segmentation
Authors: Lin Yu-e , Li Houguo , Liang Xingzhu , Li Mengfan , Liu Huilin 
Published: September 2023

Abstract
Weakly Supervised Semantic Segmentation (WSSS) is a crucial task in computer vision. However, existing methods that utilize Class Activation Maps (CAMs) with classification tasks can only identify a small part of the region. To address this limitation, we propose a novel Attention Activation Remodulation (AAR) scheme that leverages traditional CAMs and the remodulation branch to obtain weighted CAMs for recalibrated supervision. The AAR scheme re-arranges important features' distribution from the channel and space perspectives, which regulates segmentation-oriented activation responses. In addition, we propose a Feature Pixel Extraction Module (FPEM) that utilizes contextual information to improve pixel prediction. Furthermore, the proposed scheme can be combined with other methods to improve overall performance. Extensive experiments on the PASCAL VOC 2012 dataset demonstrate the effectiveness of the AAR mechanism and FPEM module.
Contemporary National Outcomes of Hyperbaric Oxygen Therapy in Necrotizing Soft Tissue Infections
Authors: Toppen William , Cho Nam Yong , Sareh Sohail , Kjellberg Anders , Medak Anthony , Benharash Peyman , Lindholm Peter 
Published: September 2023

Abstract
Background:
The role of hyperbaric oxygen therapy (HBOT) in necrotizing soft tissue infections (NSTI) is mainly based on small prospective and retrospective studies. A previous study based on the 1998-2009 National Inpatient Sample (NIS) by Soh et al found HBOT to be associated with decreased mortality in NSTI. Given the argument of advancements in critical care, we aimed to investigate the continued role of HBOT in NSTI.
Methods:
The 2012-2020 National Inpatient Sample (NIS) was queried for admissions with NSTI including only hospitalized patients who received surgery; 60,481 patients from 2012-2020 were included. Of these, 600 (<1%) underwent HBOT. The primary outcome of interest was in-hospital mortality, while secondary outcomes included amputation, hospital length of stay, and costs. A multivariate model was constructed to account for baseline differences in groups.
Results:
Age, gender, Elixhauser comorbidity index were similar between the two groups. On bivariate comparison, the HBOT group had lower mortality rate (<2% vs 5.9%, p<0.001) and lower amputation rate (11.8% vs 18.3%, p<0.001) however, longer lengths of stay (16.9 days vs 14.6 days, p<0.001) and higher costs ($54,000 vs $46,000, p<0.001) were observed. Findings persisted after adjustments for potential confounders including sepsis. After multivariate analysis, HBOT was associated with decreased mortality (Adjusted Odds Ratio (AOR) 0.22, 95% CI 0.09-0.53, P<0.001) and lower risk of amputation (AOR 0.73, 95% CI 0.55-0.96, P=0.03). While the HBO group was associated with longer stays by 1.6 days (95% CI 0.4-2.7 days) and increased costs by $7,800 (95% CI $2,200-$13,300), they also had significantly lower risks of non-home discharges (AOR 0.79, 95%CI 0.65-0.96).
Conclusions:
After correction for differences between groups, HBOT was associated with decreased mortality, amputations, and non-home discharges in NSTI with the tradeoff of modest increase to costs and length of stay.
Numerical simulations on thermocapillary flow on heated sinusoidal topography
Authors: Kim Min Chan 
Published: September 2023

Abstract
The interaction between thermocapillary flow and substrate geometry is analyzed numerically. Taking surface tension into account, the momentum equation is derived and solved using a commercial FEM solver, Comsol Multiphysics where the effects of surface tension and surface deflection can be easily incorporated into the momentum equation. In the case of Ma ≈ Ma𝑐, the strong symmetric thermocapillary flow is observed when the wavelength of topography, 𝜆𝑇, and the wavelength of instability motion, 𝜆, are nearly the same. This interesting phenomenon has been called flow-structure resonance. Through the numerical simulations, various flow modes, such as symmetric two-cell and four-cell modes, asymmetric two-cell mode, and oscillatory asymmetric two-cell mode are identified by changing the Marangoni number and wavelength of topography. It is clearly shown that for a certain 𝜆𝑇-system, the transition from oscillatory mode to steady one is possible by relaxing the previous nondeformable surface condition due to high surface tension, i.e., Cr → 0. The present study reveals that the preferred flow mode is the complex function of the various parameters such as the Marangoni number, the Biot number, the wavelength of topography, and the capillary number.
Types of behaviors and experiences at work and health condition in the group of nurses at Accident and Emergency Units
Authors: Betke Katarzyna , Prof Anna Andruszkiewicz , MA Katarzyna Adamczyk 
Published: September 2023

Abstract
Introduction
Nursing is a profession associated with a high workload and high levels of emotional tension. The way an employee functions in a professional environment is one of the many health risks. Schaarschmid and Fischer distinguished patterns of behavior and experiences in the area of ​​professional activity.
Material and Methods
The study included 150 nurses employed in Hospital Emergency Departments in central Poland. The AVEM questionnaire was used to assess the types of behavior and experiences at work, and the GHQ-28 questionnaire was used to assess the general state of mental health.
Results
The surveyed nurses most often functioned at work according to type S - economical or B - burned out, and least frequently according to type A - overloaded. The mean severity of health abnormalities was at the average level of M = 4.72 sten (SD = 1.56). The surveyed nurses did not reveal any depressive disorders, the most common health problems were social functioning disorders and complaints about somatic ailments. There were significant differences in health between nurses working in a healthy, economical or burned-out manner, especially in the experienced anxiety and insomnia as well as in the scope of depressive symptoms. Individuals functioning in accordance with type B – burned-out significantly more often complained of perceived anxiety and sleep problems than individuals functioning in accordance with type G - healthy. The analyzes showed that the intensification of complaints about the health condition can be inferred from lower education, low perfectionism in the performance of professional tasks and an increased tendency to resign in the event of failure.
Conclusion
Employers should conduct an individual analysis of the types of work behavior in the group of nurses in order to eliminate factors contributing to the deterioration of their health condition.
Hydrological Responses of the Brahmaputra River Basin using CMIP6 GCM Projections for Supporting Climate Resilient Infrastructure Design
Authors: Abdullah Faruque , Mamoon Wasif Bin , Islam AKM Saiful , Islam GM Tarekul , Bala Sujit Kumar , Kaiser Shadman , Mohammed Khaled , Billah Maruf , Das Mohan Kumar 
Published: September 2023

Abstract

Bangladesh is one of South Asia's leading countries sensitive to climate change because of its unique geography and the dominant hydro-meteorological influence of torrential monsoon rainfall. The central north of Bangladesh, which possesses low density and quality of sustainable rural infrastructures, is affected by seasonal flooding and frequent river erosions. Districts under this region are among the country's poorest and most vulnerable due to environmental stress and socioeconomic circumstances. Flooding has become a regular phenomenon in the Teesta-Brahmaputra river basin during monsoon, which causes severe damage to rural infrastructures every year. As mentioned in the latest Intergovernmental Panel on Climate Change (IPCC)’s Sixth Assessment Report (AR6), burgeoning climate variability will aggravate the situation, leaving millions more vulnerable to these extreme natural events. This study aims to assess the future impact of climate change on the discharge and water level of the Teesta-Brahmaputra river system through rigorous data processing, detailed modeling, and frequency analysis, as well as to develop a guideline for designing climate-resilient infrastructures in flood-prone areas. The Soil Water Assessment Tool (SWAT) hydrologic model is used to simulate future discharges using 13 bias-corrected General Circulation Models (GCMs) under moderate SSP2-4.5 and extreme SSP5-8.5 scenarios for near (2025–2054) and far (2071–2100) future periods with respect to baseline (1985–2014). Future water level fluctuations of six major rivers in the study region have been assessed using these flow outputs by simulating the HEC-RAS model and frequency analysis. Results indicate that the dry season will experience a more significant flow increment than the wet season under both SSP2-4.5 and SSP5-8.5 scenarios due to the impact of climate change in the Brahmaputra basin. The consequent rise in water level in the Jamuna river will vary from 38 cm in the near future (2025–2054) to 83 cm in the far future (2071–2100) for a return period of 100 years. The Old Brahmaputra, Dharala, and the Brahmaputra will also experience a sharp increase of 39 cm to 90 cm, 33 cm to 74 cm, and 25 cm to 63 cm, respectively. Based on these future projected water level values, required updates to existing design principles have been recommended for building sustainable and climate-resilient infrastructures in the study area.
Spatial and Temporal Assessment of China's Skiing Climate Resources
Authors: Yu Dandan , Lin Zhanglin , Fang Yan , Zhang Weijia , Guo Juan 
Published: September 2023

Abstract
The primary objective of this study is to analyze the characteristics of ski climate resources and quantitatively assess the suitability for skiing by utilizing a more appropriate Ski Climate Index. Taking China as a case study, this paper collected daily meteorological data from 733 weather stations spanning the period from 1991 to 2020, along with information on 415 ski resorts. Subsequently, GIS 10.5 spatial analysis tools were employed to examine the temporal and spatial variations in ski climate resources across China during this timeframe. In order to illustrate the relationship between skiing climate resources and the development of ski resorts more clearly, a comparison was thus drawn between the distribution of ski climate resources and the vitality of ski resorts in China. The results show that:1) the SCI was developed using fuzzy logic, with a predominant influence from the snow reliability facet on overall performance. Furthermore, the aesthetics and comfort facet, which includes factors such as sunshine, wind, and thermal comfort conditions, contributed to further refinement of the index. 2) Areas with high SCI values are primarily concentrated in the northwestern and northeastern regions of China, as well as certain parts of northern China. Against the backdrop of climate change, there has been a significant increase in ski climate resources in regions like Shaanxi-Gansu-Ningxia regions, southwest Tibet, and Sichuan, and noticeable declines have occurred in southern regions within Northeast China.3) Through comparison with vitality of ski resorts,SCI can partially reflect the development of ski resorts. The suitability evaluation model for skiing based on climate resources provides valuable insights for management decision-making in developing and operating ski resorts. It also offers scientific support for promoting ice-snow economic development.
Cost-reduction implicit exponential Runge-Kutta methods for highly oscillatory systems
Authors: Hu Xianfa , Wang Wansheng , Wang Bin , Fang Yonglei 
Published: September 2023

Abstract

In this paper, two novel classes of implicit exponential Runge--Kutta (ERK) methods are studied for solving highly oscillatory systems. Firstly, we analyze the symplectic conditions for two kinds of exponential integrators and obtain the symplectic method. In order to effectively solve highly oscillatory problems, we try to design the highly accurate implicit ERK integrators. By comparing the Taylor series expansion of numerical solution with exact solution, it can be verified that the order conditions of two new kinds of exponential methods are identical to classical Runge--Kutta (RK) methods, which implies that using the coefficients of RK methods, some highly accurate numerical methods are directly formulated. Furthermore, we also investigate the linear stability properties for these exponential methods. Finally, numerical results not only display the long time energy preservation of the symplectic method, but also present the accuracy and efficiency of these formulated methods in comparison with standard ERK methods.
Inhibitory effects evaluation of Thymoquinone and Nanoliposome formulation against Candida parapsilosis isolates
Authors: Shamloo Ardalan Ghiaee , Yadegari Mohammad Hossein , Jaafari Mahmoud Reza , Zarrinfar Hossein 
Published: September 2023

Abstract
Background: Candida parapsilosis as an opportunistic pathogen can cause various fungal infections, especially in immunocompromised patients. In the last few years, resistance to common antifungal drugs has been frequently reported and the aim of this study is design and synthesis of liposomal thymoquinone as an antifungal agent and evaluated the inhibitory effects on C. parapsilosisisolates.
Materials and Methods: TQ was encapsulated in liposomal formulation by using a thin-film hydration technique and then were analyzed by transmission electron microscopy (TEM), MTT assay was measured on peripheral blood mononuclear cells (PBMCs) for cell metabolic activity. The antifungal activity of TQ-Lip-NP against 15 clinical isolates of C. parapsilosis, was adjusted and examined based on the M27-A3 guideline.
Results: TQ-Lip-NP didn’t show any toxic effect on PBMCs and minimum inhibitory concentration (MIC) range of free TQ and liposomal formulation with inhibitory effects on Candida isolates was between 50 to 6.25 µg/mL and 150 to 18.75, respectively the MIC50 and MIC90 values of free TQ and TQ-Lip-NP were also 25, 50, and 75, 150 µg/mL.
Conclusion: Finally, we demonstrated the good efficacy of synthesized TQ-Lip-NP with significant antifungal activity against C. parapsilosiscomplex isolates compared to free TQ.