bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occurrence of Thelazia callipaeda and its vector Phortica variegata in Austria and South Tyrol, Italy, and a global comparison by phylogenetic network analysis
Authors: Unterköfler Maria Sophia , Dengg Patrick , Niederbacher Miriam , Lindorfer Sarah , Eberle Antonia , Huck Alexandra , Staufer Katalina , Zittra Carina , Wortha Licha Natalia , Hodžić Adnan , Duscher Georg Gerhard , Harl Josef , Schlüsslmayr Gerhard , Bezerra-Santos Marcos Antonio , Otranto Domenico , Silbermayr Katja , Fuehrer Hans-Peter 
Published: August 2023

AbstractThe zoonotic nematode Thelazia callipaeda infects the eyes of domestic and wild animals and uses canids as primary hosts. It was originally described in Asia, but in the last 20 years it has been reported in many European countries, where it is mainly transmitted by the drosophilid fruit fly Phortica variegata. We report the autochthonous occurrence of T. callipaeda and its vector P. variegata in Austria. Nematodes were collected from clinical cases and fruit flies were caught using traps, netting, and from the conjunctival sac of one dog. Fruit flies and nematodes were morphologically identified and a section of the mitochondrial cytochrome c oxidase subunit I gene (COI) was analysed. A DNA haplotype network was calculated to visualize the relation of the obtained COI sequences to published sequences. Additionally, Phortica spp. were screened for the presence of DNA of T. callipaeda by polymerase chain reaction. Thelazia callipaeda and P. variegata were identified in Burgenland, Lower Austria, and Styria. Thelazia callipaeda was also documented in Vienna and P. variegata in Upper Austria and South Tyrol, Italy. All T. callipaeda corresponded to haplotype 1. Twenty-two different haplotypes of P. variegata were identified in the fruit flies. One sequence was distinctly different from those of Phortica variegata and was more closely related to those of Phortica chi and Phortica okadai. Thelazia callipaeda could not be detected in any of the Phortica specimens.
Graphical Abstract
To predict the left ventricular endocardial scar tissue pattern using Radon descriptor-based machine learning
Authors: Singh Yashbir , Atalla Shadi , Mansoor Wathiq , Paul Rahul , Deepa Deepa 
Published: August 2023

Abstract
Objective
Scar tissue is an identified cause for the development of malignant ventricular arrhythmias in patients of myocardial infarction, which ultimately leads to cardiac death, a fatal outcome. We aim to evaluate the left ventricular endocardial Scar tissue pattern using Radon descriptor-based machine learning. We performed automated Left ventricle (LV) segmentation to find the LV endocardial wall, performed morphological operations, and marked the region of the scar tissue on the endocardial wall of LV. Motivated by a Radon descriptor-based machine learning approach; the patches of 17 patients from Computer tomography (CT) images of the heart were used and categorized into “endocardial Scar tissue” and “normal tissue” groups. The ten feature vectors are extracted from patches using Radon descriptors and fed into a traditional machine learning model.

Results
The decision tree has shown the best performance with 98.07% accuracy. This study is the first attempt to provide a Radon transform-based machine learning method to distinguish patterns between “endocardial Scar tissue” and “normal tissue” groups. Our proposed research method could be potentially used in advanced interventions.
Selective breeding can contribute to bovine tuberculosis control and eradication
Authors: Banos Georgios 
Published: August 2023

AbstractBovine tuberculosis (bTB) persists in many countries having a significant impact on public health and livestock industry finances. The incidence and prevalence of new cases in parts of the UK and elsewhere over the past decades warrant intensified efforts towards achieving Officially Tuberculosis Free (OTF) status in the respective regions. Genetic selection aiming to identify and remove inherently susceptible animals from breeding has been proposed as an additional measure in ongoing programmes towards controlling the disease. The presence of genetic variation among individual animals in their capacity to respond to Mycobacterium bovis exposure has been documented and heritability estimates of 0.06-0.18 have been reported. Despite their moderate magnitude, these estimates suggest that host resistance to bTB is amenable to improvement with selective breeding. Although relatively slow, genetic progress can be constant, cumulative and permanent, thereby complementing ongoing disease control measures. Importantly, mostly no antagonistic genetic correlations have been found between bTB resistance and other animal traits suggesting that carefully incorporating the former in breeding decisions should not adversely affect bovine productivity. Simulation studies have demonstrated the potential impact of genetic selection on reducing the probability of a breakdown to occur or the duration and severity of a breakdown that has already been declared. Furthermore, research on the bovine genome has identified multiple genomic markers and genes associated with bTB resistance. Nevertheless, the combined outcomes of these studies suggest that host resistance to bTB is a complex, polygenic trait, with no single gene alone explaining the inherent differences between resistant and susceptible animals. Such results support the development of accurate genomic breeding values that duly capture the collective effect of multiple genes to underpin selective breeding programmes. In addition to improving host resistance to bTB, scientists and practitioners have considered the possibility of reducing host infectivity. Ongoing studies have suggested the presence of genetic variation for infectivity and confirmed that bTB eradication would be accelerated if selective breeding considered both host resistance and infectivity traits. In conclusion, research activity on bTB genetics has generated knowledge and insights to support selective breeding as an additional measure towards controlling and eradicating the disease.
Prevalence of dementia, heart disease and stroke in community-dwelling adults in Canada, 2016–2021: opportunities for joint prevention
Authors: Singh Sarah S. , Zhong Shiran , Rogers Kem A. , Hachinski Vladimir C. , Frisbee Stephanie J. 
Published: August 2023

Abstract
Introduction
This aim of this study is to provide updated estimates on the prevalence of dementia, heart disease, and stroke in Canadian communities. Targeting all three conditions together, at the community level, may be key to disease prevention and health aging in the Canadian population.

Methods
Using nationwide health survey data, we calculated the age-standardized prevalence of self-reported dementia, heart disease and stroke in adults aged 18 years and over residing in Canadian communities from 2016 to 2021. Poisson regression models were used to detect statistically significant changes in the prevalence of all three conditions from 2016 to 2021.

Results
Less than 1% (~ 175,000 individuals) of adults residing in Canadian communities reported dementia, 5% (~ 1.5 million individuals) reported heart disease, and more than 1% (~ 370,000 individuals) reported stroke annually from 2016 to 2021. Overall, the age-standardized prevalence for stroke decreased minimally from 2016 to 2021 (p = 0.0004). Although the age-standardized prevalence of heart disease and dementia decreased from 2016 to 2018, subsequent increases in prevalence from 2018 to 2021 led to a lack of overall statistically significant changes from 2016 to 2021 (p = 0.10 for heart disease and p = 0.37 for dementia).

Conclusion
Recent increases in the prevalence of dementia, heart disease and stroke in Canadian communities threaten to reverse any gains in vascular disease prevention over the past six years. Findings reveal the urgent need for intensified prevention efforts that are community-based with a focus on joint reduction in the shared risk factors contributing to all three diseases.
On the flow conditions requiring detailed geometric modeling for multiscale evaluation of coastal forests
Authors: Nomura Reika , Takase Shinsuke , Moriguchi Shuji , Terada Kenjiro 
Published: August 2023

AbstractThe multiscale evaluation method is applied to assess the influence of detailed geometric modeling of trees on their macroscopic attenuation effect against tsunami-like flow. Specifically, we conduct a series of numerical flow tests (NFTs), i.e., 3D flow simulations in a local test domain (LTD), under various inflow conditions to evaluate the macroscopic flow characteristics in the LTD accommodating an array of either simple cylinder or detailed tree models that mimic a coastal forest. After the procedure of NFTs in the multiscale evaluation method is briefly summarized and the corresponding governing equations and analysis conditions are presented, we introduce two indices for evaluating the macroscopic flow characteristics within the framework of multiscale modeling. Based on the NFT results, we discuss how the modeling scheme for trees influences the macroscopic flow characteristics in terms of these indices and clarify the microscopic mechanisms that influence the macroscopic attenuation property. Additionally, the NFT results are compared with the experimental results to justify these discussions, and key factors are explored in terms of reproducing real phenomena. In addition, to apply the multiscale evaluation method to assess the disaster mitigation performance of various types of ecosystems in a realistic situation, we discuss under what circumstances and with what level of detail vegetation should be modeled.
Comparison of the Miniaci and Dugdale techniques on functional outcomes in medial open wedge high tibial osteotomy
Authors: Aygün Ümit , Bölükbaşı Murat , Yamak Kamil , Çiçek Ali Can 
Published: August 2023

AbstractPurposeTo compare the correction angles determined by the Miniaci and Dugdale techniques in patients treated with medial open wedge high tibial osteotomy (MOWHTO) and show their impact on clinical outcomes.MethodsSeventy‐four patients constituted the study group. The correction angles in Group 1 were measured using the Miniaci technique, and those in Group 2 were measured using the Dugdale technique. The clinical evaluations included the Tinetti Gait and Balance Assessment (TGBA), the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) scores, and the Visual Analogue Scale (VAS). The effect of the correction angle on the patient's clinical outcomes was evaluated. Measurement techniques were also changed between groups for comparison.ResultsSeventy‐four patients (62 females, 12 males) with a mean age of 53.7 ± 4.9 years were followed up for a mean of 67.4 ± 5.5 months. The TGBA, WOMAC, and VAS scores were improved at the last follow‐up compared to the preoperative scores (p < 0.05). The preoperative TGBA and WOMAC scores were not significantly different between the two groups, but the last follow‐up TGBA and WOMAC scores in Group 2 were worse than those in Group 1 (p < 0.05). When measuring techniques were changed, the preoperative correction angle (PCA) value and the last follow‐up correction angle (LFCA) value were lower in Group 1 measured with the Dugdale technique but higher in Group 2 measured with the Miniaci technique (p < 0.05).ConclusionSince the correction angle values measured with the Miniaci technique in MOWHTO are higher than those measured with the Dugdale technique; the functional results are better.Level of evidenceRetrospective cohort study, III.
Development of human-touch smart armband for tele-haptic communication using a fabric-based soft pneumatic actuator
Authors: Choi Hanna , Yoo Shinjung 
Published: August 2023

AbstractThis study aimed to develop a human-touch smart armband that can transport emotional tactile stimuli to individuals in distant places. To simulate human touch stimuli, a soft pneumatic actuator (SPA) which we refer to in this study as “SPA touch,” of size 7 cm × 7 cm and thickness 0.3 cm was designed using fabric and silicone with nine touch points, which can be individually inflated and allocated within the actuator. The use of thermoplastic polyurethane-coated fabric as a backing material helps obtain one-side inflation toward the skin effectively. By controlling the position and duration time of the inflation of the nine touch points, three basic touch modes (“Touch,” “Double touch,” and “Drag”) and three emotional tactile gestures (“Patting,” “Hugging,” and “Caressing”) were programmed using Python. The evaluation of the operating performance of the basic touch modes and emotional tactile gestures showed that “SPA touch” could properly create and transmit touch stimulation remotely. The human-touch smart armband developed in the process of this study can be used for novel tele-haptic communication with individuals in distant places, such as nursing homes.
Effects of morphological traits on body weight and analysis of growth-related genes of Parabramis pekinensis at different ages
Authors: Xu Wentao , Feng Yaming , Gu Zhengyan , Zhang Shuanglin , Yang Zhijing , Xu Ye , Gu Hailong 
Published: August 2023

AbstractParabramis pekinensis was treated as research object in order to investigate the correlation between morphological traits and body weight. We measured 9 morphological indexes including total length (X1), body length (X2), body height (X3), head length (X4), snout length (X5), eye diameter (X6), eye distance (X7), caudal stalk length (X8) and caudal stalk height (X9). The principal morphological traits affecting body weight were screened out and the regression equation was established. The regression equation of Y1 (age 1 group) shape character (X) and weight (Y) was Y = − 169.183 + 32.544 × 3 + 10.263 × 4 + 15.655 × 7. The regression equation of Y2 (age 2 group) shape character (X) and weight (Y) was Y = − 694.082 + 7.725 × 1 + 72.822 × 3 + 77.023 × 6, the regression equation of Y3 (age 3 group) shape character (X) and weight (Y) was Y = − 1161.512 + 26.062 × 1 + 22.319 × 2- 107.218 × 5 + 83.901 × 7. Gene expression was consistent with these conclusions. TOR signaling pathway expression raised in Y1 then width increased. And GH-IGF-1 signaling pathway expression raised in Y2 then the length increased. In conclusion, the paper could prove that P. pekinensis showed a growth trend, which was increasing width first and length later. In some sense, the study not only enriched the basic biological data of P. pekinensis, but also provided waiting morphological traits for selective breeding of P. pekinensis artificial breeding in future.
Fungal endophytes as potential biocontrol agent of Panama disease of banana
Authors: Taping Jonah Mae F. , Borja Bernadith T. , Bretaña Bryan Lloyd P. , Tanabe Maria Elena N. , Cabasan Ma. Teodora N. 
Published: August 2023

Abstract
Background
Fusarium odoratissimum (Foc TR4) is a devastating fungal pathogen that causes Panama wilt in Cavendish banana, a high value crop that generates significant revenue. The excessive use of synthetic fungicides for disease control poses risks to both human health and the environment. Consequently, there is a pressing need for eco-friendly alternatives to manage this disease. One potential approach is the utilization of biocontrol agents, which have shown promise in disease control. This study aimed to evaluate the biocontrol potential of fungal endophytes isolated from the naturally-resistant cultivar Cardaba banana against Foc TR4. These fungal isolates were subjected to a dual culture assay, characterized based on morpho-cultural characteristics, and confirmed molecularly using the internal transcribed spacer (ITS) region of rDNA.

Results
Of the 15 fungal endophytes isolated from Cardaba; Blakeslea trispora, Pseudopestalotiopsis theae, Xylaria badia, Nigrospora hainanensis, Colletotrichum gloeosporioides, Xylaria feejeensis, Gymnoascus reessii, Fusarium subglutinans, Rigidoporus vinctus, and Macrophomina phaseolina showed potential antagonistic activity against F. odoratissimum. Isolates X. feejeensis (USMJMTBL10), G. reesii (USMJMTBL11), and M. phaseolina (USMJMTBR1) had the highest antagonistic activity of 87.8–96.6% against F. odoratissimum in vitro.

Conclusion
This study presents evidence of the potential of Cardaba-associated endophytes isolated and identified in this research, as effective biocontrol agents against F. odoratissimum, the causal agent of Panama disease in Cavendish banana. Our findings suggest that these endophytes hold promise as a biocontrol agent for managing Foc TR4-infected banana plants. Future research will focus on in planta testing, validation in greenhouse and field trials, as well as development of formulations and application protocols to optimize the utilization of these biocontrol agents in an integrated management approach for Foc TR4-infected bananas.
"Lepet": Indonesian traditional food for Eid Al-Fitr celebrations
Authors: Wardana Ata Aditya , Setiarto R. Haryo Bimo , Wigati Laras Putri 
Published: August 2023

AbstractIndonesia, a country with diverse cultures, possesses a rich variety of cultural heritage. The aim of this review is to discuss the culture oflepetconsidering its ethnic perspective, preparation and consumption, nutritional and functional properties, safety, and future outlook aspects.Lepet, a traditional Javanese dish, consists of sticky rice, grated young coconut, coconut milk, cowpea, and salt. It is wrapped in young coconut leaves with a specific pattern, boiled, soaked, and then hung to cool and dry. The persuasive technique employed by Sunan Kalijaga, which combines Javanese cultural traditions and Islamic religious teachings, symbolizeslepetfor the Javanese people. This method facilitated the spread of Islam by emphasizing the importance of purity and refraining from committing further mistakes after apologizing during theEid Al-Fitritradition.Lepetis rich in carbohydrates and some protein. It is gluten-free and offers benefits for bone and skin health due to its contribution of antioxidants, vitamins, and minerals. Proper handling and storage oflepetare vital to prevent the growth of harmful bacteria and extend its shelf life. Given the rising worldwide acknowledgment of Indonesian gastronomy, advancements in technology and distribution, creative adaptations, and a surging demand for convenience, the prospects forlepetappear bright in the future.
Factors affecting HBV DNA suppression in chronic hepatitis B patients treated with tenofovir disoproxil fumarate
Authors: Darmadi Darmadi , Lindarto Dharma , Siregar Jelita , Widyawati Tri , Rusda Muhammad , Amin Mustafa Mahmud , Yusuf Fauzi , Eyanoer Putri Chairani , Lubis Masrul , Rey Imelda 
Published: August 2023

Background: This study aims to determine the factors affecting HBV DNA suppression in chronic hepatitis B patients with tenofovir disoproxil fumarate (TDF). Methods: A case-control was carried out from October 2021 to August 2022 on 182 chronic hepatitis B patients who had TDF therapy regularly for 24 weeks at H. Adam Malik and USU Hospitals in Medan, Indonesia. The history of the samples was obtained, followed by physical examination, and blood collection. CTLA-4 polymorphism examination was carried out using real-time PCR, while the serum CTLA-4 levels were assessed with ELISA. Results: The CTLA-4 -1661G>A polymorphism, genotype GG+AG, increased 1.52 times risk of not achieving HBV DNA suppression to TDF compared to genotype AA (p=0.041). High CTLA-4 levels increased 2.28 times risk, high HBV DNA levels increased 2.09 times risk, low ALT levels increased 1.95 times risk of not achieving HBV DNA suppression (p= 0.009, 0.026, 0.036, respectively). There was no relationship between gender, age, ethnicity, obesity, baseline AST, HBeAg, genotype, liver fibrosis and HBV DNA suppression after 24 weeks of treatment (p>0.05). Conclusions: The levels of CTLA-4, HBV DNA, ALT, and CTLA-4 -1661G>A polymorphism have a potential relationship with the suppression of HBV DNA in chronic hepatitis B patients with TDF.
Are conspiracy theorists inaccurate, unmotivated to be accurate, or both?: A latent class analysis
Authors: Bowes Shauna , Fazio Lisa 
Published: August 2023

Background: A rapidly growing body of research demonstrates that conspiratorial ideation is related to less accuracy, more overconfidence, and more reliance on intuition. Yet, the bulk of this research has focused on belief in conspiracy theories rather than conspiracy theorists. As such it remains unclear whether all conspiracy theorists are equally inaccurate, overconfident, and reliant on intuition or whether there are types of conspiracy theorists who differ across these variables. Methods: To address this gap in the literature, we conducted a preregistered secondary data analysis of the variable-level and person-centered relations among conspiratorial ideation, accuracy, overconfidence, and motivations across five samples (Ns ranged from 477 to 3,056). We used multiple measures of each variable to build in conceptual replication. Results: Broadly, the variable-centered results were consistent with existing research and revealed that conspiratorial ideation tended to be related to less accuracy, more overconfidence, more reliance on intuition and closemindedness, and less rational thinking and open-mindedness. In person-centered analyses, we found two classes of individuals, one who scored higher on conspiratorial ideation and one who scored lower. In the conspiracy theorist class, we found that conspiracy theorists were not unknowledgeable and irrational across the board. Conclusions: Thus, conspiracy theorists may be more psychologically complex than originally presumed based on variable-level results. Future research is needed to examine how different motives manifest in conspiracy theorists and to leverage insights from such research to reduce susceptibility to misinformation.
Venous malformations in children - a literature review
Authors: Dobek Adam , Korol Filip , Symulewicz Michał , Edyko Krzysztof , Jachowicz Krzysztof , Minkner Mikołaj , Bieńkowski Borys , Feja Krzysztof , Marchewka Urszula , Łuczak Ewa 
Published: August 2023

Introduction:
Venous malformations are congenital, the most occurring subtype of vascular malformations. They are characterized by slow flow, tortuosity and lack of macular layer within the vessel. Venous malformations can be highly problematic to diagnose and treat, thus differentiation the venous malformations with other diseases in pediatric population is important.
Aim of the study:
The aim of the study is to summarize the available knowledge about venous malformation in pediatric population. The options in diagnosis, treatment and potential new methods were summarized and described.
Materials and methods
The literature available in the PubMed database was reviewed using the following keywords: “Vascular malformations”, “Venous Malformations”, “Venous malformations treatment, “Children”.
Conclusions:
Venous malformations are an important problem in pediatric population, as a seldom affliction they can be easily misdiagnosed as other diseases and treated inadequately. Widening of awareness of venous malformations and possible methods of diagnosing and treating them is very important to raise quality of health care in children.