bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison between gaits after a medial pivot and posterior stabilized primary total knee arthroplasty: a systematic review of the literature
Authors: Risitano Salvatore , Cacciola Giorgio , Capella Marcello , Bosco Francesco , Giustra Fortunato , Fusini Federico , Indelli Pier Francesco , Massé Alessandro , Sabatini Luigi 
Published: March 2023

Abstract
Background
Total knee arthroplasty (TKA) is one of the most performed orthopedic procedures worldwide. While excellent efficacy has been reported, about 20% of patients are not satisfied with the result. A potential cause is the problematic reproduction of knee kinematics. This systematic review examines gait analysis studies in primary medial pivot (MP) and posterior stabilized (PS) TKAs to investigate the differences between the two prosthesis designs.

Methods
A systematic review was conducted by following PRISMA guidelines. Five databases (PubMed, Medline, Embase, Scopus and the Cochrane Database of Systematic Reviews) were analyzed, and eligible articles were evaluated in terms of the levels of evidence. The methodological quality of the articles was assessed by using the MINORS scoring. This review was registered in PROSPERO.

Results
Nine studies were included. Gait analysis was performed in 197 MP TKA and 192 PS TKA patients. PS TKA cases showed (P < 0.05) a significantly higher peak of knee flexion angle during the swing phase, greater knee flexion angle at toe-off, an increased knee adduction angle, higher knee flexion and extension moment, increased anterior femoral roll during knee flexion and anterior translation on medial and lateral condyle during knee flexion compared to MP TKA. MP TKA showed statistically significant (P < 0.05) higher knee rotational moment and greater tibiofemoral external rotation motion during knee flexion than PS TKA. No statistically significant difference (P > 0.05) was reported regarding gait spatial–temporal parameters. The Forgotten Joint Score (FJS) and Western Ontario and McMaster Universities Comparison in terms of Arthritis Index (WOMAC) score (mean stiffness) showed that MP TKA yielded significantly better results than PS TKA.

Conclusions
This systematic review revealed significant kinematic and kinetic differences between MP and PS TKA at all gait analysis phases. Furthermore, the considerable difference between TKA design and the kinematics of healthy knee were highlighted in this study.

Level of evidence
III.
Erdheim-Chester Disease With BRAF V600E Mutation and Central Diabetes Insipidus Successfully Treated With Glucocorticoid
Authors: Imaizumi Toshinori , Daido Hisashi , Kato Takehiro , Yabe Daisuke 
Published: March 2023

Abstract
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by xanthoma/xanthogranuloma infiltration in various organs and a broad spectrum of clinical presentations, including bone lesions, central diabetes insipidus and renal failure. BRAF V600E mutation is seen in almost half of the cases of ECD; the BRAF inhibitor vemurafenib is recommended treatment in the United States and the European Union. However, the indication for vemurafenib in Japan is limited to unresectable malignant melanoma with BRAF mutation. Although glucocorticoids, interferon, chemotherapy, and radiation therapy are treatment options, no standard therapy for ECD has yet been established in Japan. We describe here a patient with central diabetes insipidus and retroperitoneal lesions who was successfully treated with prednisolone. Glucocorticoid therapy is therefore a plausible alternative for ECD with BRAF V600E mutation when the BRAF inhibitor vemurafenib cannot be used.
Sonolucent Cranioplasty in Extracranial to Intracranial Bypass Surgery: Early Multicenter Experience of 44 Cases
Authors: Salem Mohamed M. , Ravindran Krishnan , Hoang Alex Nguyen , Doron Omer , Esparza Rogelio , Raper Daniel , Jankowitz Brian T. , Tanweer Omar , Lopes Demetrius , Langer David , Nossek Erez , Burkhardt Jan-Karl 
Published: March 2023

BACKGROUND:
The new sonolucent cranioplasty implant (clear polymethyl methacrylate, PMMA) adds functionality besides surgical reconstruction. One possible application uses the transcranioplasty ultrasound (TCUS) technique after PMMA cranioplasty to assess graft patency of extracranial-intracranial (EC-IC) bypass procedures.

OBJECTIVE:
To report our early multicenter experience.

METHODS:
This is a multicenter analysis of consecutive EC-IC bypass patients from 5 US centers (2019-2022) with closure postbypass using PMMA implant.

RESULTS:
Forty-four patients (median age 53 years, 68.2% females) were included. The most common indication for bypass was Moyamoya disease/syndrome (77.3%), and superficial temporal artery to middle cerebral artery bypass was the most common procedure (79.5%). Pretreatment modified Rankin Scales of 0 and 1 to 2 were noted in 11.4% and 59.1% of patients, respectively. Intraoperative imaging for bypass patency involved a combination of modalities; Doppler was the most used modality (90.9%) followed by indocyanine green and catheter angiography (86.4% and 61.4%, respectively). Qualitative TCUS assessment of graft patency was feasible in all cases. Postoperative inpatient TCUS confirmation of bypass patency was recorded in 56.8% of the cases, and outpatient TCUS surveillance was recorded in 47.7%. There were no cases of bypass failure necessitating retreatment. Similarly, no implant-related complications were encountered in the cohort. Major complications requiring additional surgery occurred in 2 patients (4.6%) including epidural hematoma requiring evacuation (2.3%) and postoperative surgical site infection (2.3%) that was believed to be unrelated to the implant.

CONCLUSION:
This multicenter study supports safety and feasibility of using sonolucent PMMA implant in EC-IC bypass surgery with the goal of monitoring bypass patency using TCUS.
Septins and K63 ubiquitin chains are present in separate bacterial microdomains during autophagy of entrapped Shigella
Authors: Lobato-Márquez Damián , Conesa José Javier , López-Jiménez Ana Teresa , Divine Michael E. , Pruneda Jonathan N. , Mostowy Serge 
Published: March 2023

ABSTRACT
During host cell invasion, Shigella escapes to the cytosol and polymerizes actin for cell-to-cell spread. To restrict cell-to-cell spread, host cells employ cell-autonomous immune responses including antibacterial autophagy and septin cage entrapment. How septins interact with the autophagy process to target Shigella for destruction is poorly understood. Here, we employed a correlative light and cryo-soft X-ray tomography (cryo-SXT) pipeline to study Shigella septin cage entrapment in its near-native state. Quantitative cryo-SXT showed that Shigella fragments mitochondria and enabled visualization of X-ray-dense structures (∼30 nm resolution) surrounding Shigella entrapped in septin cages. Using Airyscan confocal microscopy, we observed lysine 63 (K63)-linked ubiquitin chains decorating septin-cage-entrapped Shigella. Remarkably, septins and K63 chains are present in separate bacterial microdomains, indicating they are recruited separately during antibacterial autophagy. Cryo-SXT and live-cell imaging revealed an interaction between septins and LC3B-positive membranes during autophagy of Shigella. Together, these findings demonstrate how septin-caged Shigella are targeted for autophagy and provide fundamental insights into autophagy–cytoskeleton interactions.
Measurement of voluntary bite forces in large carnivores using a semi-automated reward-driven system
Authors: van der Meijden Arie , González-Gómez Julio César , Pulido-Osorio María D. , Herrel Anthony 
Published: March 2023

ABSTRACT
Bite force is a key performance trait of the feeding system, but maximal in vivo bite force has been measured in few large mammals. The alternative, modelling of bite force from anatomy, cannot be validated without in vivo measurements. To overcome existing limitations of ethics, safety and animal well-being, we propose a semi-automated method to obtain voluntary maximum bite forces from large mammals using bite plates that automatically dispense a food reward if an incrementally increasing threshold force value is reached. We validated our method using two Malayan sun bears, two Andean spectacled bears and a lioness. We show that voluntary bite force measurement using positive reinforcement is a non-invasive and reliable method to record maximum voluntary bite force performance in large mammals. Our results further show that in vivo data are critical as modeling efforts from osteology have greatly underestimated bite forces in Andean spectacled bears.
Physiotherapy interventions for head and trunk control in children with developmental disabilities: A scoping review protocol
Authors: Shakya Shristi , Parsekar Shradha S. , Ramachandran Selvam , Madapura S. Shamantha , Balakrishna Shetty Harikishan , Anaby Dana , Gopalakrishna Sivakumar , Venkatesan V. S. , Rao Bhamini Krishna 
Published: March 2023

Background: Head and trunk control is prerequisite skill that maximizes engagement and participation in one’s environment by integrating vision, oromotor skill, arm control and respiration. Various physiotherapy and technology-based interventions have been utilized to facilitate head and trunk control in children with developmental disabilities. This scoping review is planned to map and summarize existing studies from the scientific literature on physiotherapy and technology-based interventions for head and trunk control in children with developmental disabilities. Methods: The scoping review will utilize the Joanna Briggs Institute scoping review methodology. The review will cover studies including children and adolescents aged between six months and 17 years 11 months 29 days, with developmental disabilities where in child finds difficulty in lifting its head and aligning head and trunk. We will include randomized controlled trial (RCT), non-RCT, quasi-experimental trial, and systematic reviews that have employed physiotherapy and technology-based interventions. Database-specific search strategy will be used to search records in Medline (PubMed and Web of Science), Embase, Scopus, CINAHL, PEDro, and Cochrane Library. Additionally, various grey literatures and clinical-trial registries will be searched. Two reviewers, independently, will screen and extract the data. Tables and visual representations will be utilized to present the extracted data. Registration details: The protocol has been registered in Open Science Framework, DOI: 10.17605/OSF.IO/B3RSU (22nd August 2022)
Queervertising: An empowerment tool for the gay men and lesbian community
Authors: Iglesias-Sánchez Patricia P. , Jambrino-Maldonado Carmen , de las Heras-Pedrosa Carlos , Díaz-Tendero Rafael 
Published: March 2023

Background: Today’s society clams to be more inclusive, but there has been a lack of practical examination of this area. This study analyses how advertising and society interact and evolve in parallel, with advertising seeking to balance more traditional representations – in accordance with the Mirror Theory – with mainstreaming, which can influence social change. In this case, analysis is focused on the homosexual community. Methods: A content analysis of audiovisual advertising in Spain from the 1960s to 2021 is carried out in addition to a review of historical milestones and legislation. Results: The results evidence the transformation of advertising. The main findings show a shift from the total invisibility of the gay men and lesbian community in the 1960s to effective and respectful integration today. Conclusions: Queervertising is proposed as a new theoretical concept as the result of gender and sexual diversity being identified in advertising over time. The inclusion of gay men and lesbians in advertising is a current trend that, moreover, offers a challenge for brands. Although this turnaround in advertising creativity should be highlighted and recognized as being to some extent responsible for changes and social evolution, the commercial messages which are found today are still not always disruptive or excessively explicit, in order to avoid some rejection by audiences.
Diferencias de representación de género entre las películas españolas dirigidas por hombres y por mujeres (2018-2019)
Authors: Marcos Ramos María , Martín García Teresa , González de Garay Beatriz 
Published: March 2023

Desde hace unos años se viene gestando un movimiento social que reclama una mayor diversidad en la sociedad, incluido el cine. Así, miembros de minorías reclaman su espacio como creadores de contenidos. Diversas organizaciones han señalado que si hay más mujeres en la dirección de películas, habrá más películas protagonizadas por mujeres. Empero, no hay evidencia científica de ello, y este estudio quiere comprobar si existe una relación directa entre el género del director y los personajes. El objetivo fue estudiar la representación de género en el cine español a través de la relación entre la representación de personajes femeninos/masculinos y el género de los directores. Se analizó el contenido de 30 películas españolas de 2018 y 2019 con un total de 468 caracteres (n = 468). Se concluyó que, aun cuando sigue existiendo una infrarrepresentación de personajes femeninos, no existe una relación estadística significativa entre esta infrarrepresentación y el género de los consejeros. Además, no hubo una relación estadística significativa entre el género del director y la ocupación del personaje u objetivos personales vs. laborales. En comparación con las películas de directoras, en el trabajo de los directores masculinos, la frecuencia de diálogo entre personajes femeninos y masculinos es significativamente mayor.
Burden and severity of deranged electrolytes and kidney function in children seen in a tertiary hospital in Kano, northern Nigeria
Authors: Obiagwu Patience N. , Morrow Brenda , McCulloch Mignon , Argent Andrew 
Published: March 2023

Introduction
Derangement in serum electrolytes and kidney function is often overlooked, especially in resource-constrained settings, and associated with increased risk of morbidity and mortality. This study aimed to describe the burden of derangements in serum electrolytes and kidney function in children presenting to a tertiary hospital in Nigeria.

Methods
The laboratory records of all children who had serum electrolytes urea and creatinine ordered on their first presentation to hospital between January 1 and June 30, 2017 were retrospectively reviewed. Basic demographic data including admission status (inpatient or outpatient) were recordedandserum levels of sodium, potassium, chloride and bicarbonate were assessed for derangements usingnormal values from established reference ranges. Results of repeat samples were excluded. Kidney function was classified based on the serum creatinine relative to normal values for age and sex.

Results
During the study period, 1909 children (60.3% male); median (IQR) age 42 (11.9) months had serum chemistry and 1248 (65.4%) were admitted. Results of their first samples were analyzed. Electrolyte derangements were present in 78.6% of the samples most commonly hyponatraemia (41.1%), low bicarbonate(37.2%), hypochloraemia (33.5%) and hypokalemia(18.9%). Azotaemia was found in 20.1% of the results. Elevated serum creatinine levels were found in 399 children (24.7%), 24.1% of those being in the severe category. Children aged 5 years and younger accounted for 76.4% of those with derangement in kidney function. One hundred and eight outpatients (17.8%) had deranged kidney function.

Conclusion
Deranged serum electrolytes and kidney function were common in this cohort.
Resolving the Costs of the Action by Mediation not Litigation
Authors: Mallalieu Roger , Campbell Colin 
Published: March 2023

This article considers the role of mediation in resolution of the quantum of costs in civil proceedings in the courts of England and Wales as an alternative to detailed assessment by a judge under the Civil Procedure Rules 1998. The benefits of mediation are reviewed by carrying out a comparison with the court process, emphasizing the speed, costs savings, informality and privacy which resolution other than going to court can deliver. The article also comments upon whether making mediation in costs mandatory would assist parties who pay and receive costs, and whether this is likely to happen in the foreseeable future.
Keywords: civil procedure; legal costs; detailed assessment; alternative dispute resolution; costs mediation.
Determination of nicotine content in locally produced smokeless tobacco (Shammah) samples from Jazan region of Saudi Arabia using a convenient HPLC-MS/MS method
Authors: Alhazmi Hassan A. 
Published: March 2023

Abstract
Shammah is one of the forms of smokeless tobacco (SLT) prepared by mixing tobacco powder with other ingredients to increase its acceptability. Nicotine (NT) is the main alkaloid present in tobacco and is a precursor for carcinogenic metabolites including tobacco specific nitrosamines (TSNAs). In this study, eight varieties of Shammah samples, collected from Jazan region of Saudi Arabia, were analyzed for NT content by a validated high performance liquid chromatography-mass spectrometry/mass spectrometry method. Electrospray ionization was used with the multiple reaction monitoring in the positive mode for data acquisition. The method was fast and short retention times (RT) of 1.4 and 3.1 min were observed for NT and lapatinib used as internal standard (IS), respectively. The inter- and intra-day accuracy and precision results met the acceptance criteria of United States Food and Drug Administration and International Council for Harmonisation validation guidelines. The developed method was successfully applied for the detection of NT contents in various Shammah samples. NT concentration was found to be in the range of 6.94 ± 0.16 to 31.69 ± 0.79% with the maximum level detected in special Shammah from Ahad Al Masarihah and the lowest level in Khadrah Shammah from Samtah city. The results of this investigation have warranted further research to determine the minor Shammah contents including additive materials and assessment of associated health effects.
Statistical analysis of the repeatability of the crevice corrosion repassivation potential
Authors: Rodríguez Martín A. 
Published: March 2023

Abstract
An extensive database of crevice corrosion repassivation potentials (E
R,CREV) of corrosion-resistant and high-temperature alloys was analysed with statistical tools. Repeatability of results, which considers multiple tests performed by the same team with the same experimental setup, was assessed. Evaluated variables include those that allegedly affect the outcome of testing techniques used to determine E
R,CREV such as crevice formers material, applied torque, the extent of corrosion propagation before repassivation and electrochemical procedures; and environmental and metallurgical conditions that may change the corrosion susceptibility of materials such as thermal ageing, alloy composition, temperature, chloride concentration and inhibitors. Guidelines to decide on the significance of changes in crevice corrosion repassivation potentials are proposed. Analysis of collected data suggests that a sample size of 5 is appropriate for assessing any change in the environmental or metallurgical conditions on the repassivation potential.
Activating calcium-sensing receptor gene variants in China: a case report of hypocalcaemia and literature review
Authors: Guo Shuzhen , Li Xiaolin , Shan Xiaoou 
Published: March 2023

Abstract

Objectives
Autosomal dominant hypocalcaemia 1 (ADH1) is a rare autosomal dominant genetic disease, due to the activating mutations of the calcium-sensing receptor (CASR) gene. The current paper presents a severe case of ADH1 with intellectual backwardness, and systematically reviews the reported 17 ADH1 patients in China.

Case presentation
A 7 years old boy with recurrent seizures over 1 year was admitted at Yuying children’ hospital, the clinical centre of south province of Zhejiang. Auxiliary examinations demonstrated hypocalcaemia, hyperphosphatemia, hypomagnesemia, hypercalciuria, low parathyroid hormone (PTH), basal ganglia calcifications, normal range of serum creatinine, and 25-hydroxyvitamin D. Wechsler’s intelligence test result indicated intellectually backward. The patient’s genotype found a heterozygous variant in CASR gene, c.T416C p. (Ile139Thr). This article also systematically reviews the literatures on ADH1 in China and summarises the clinical characteristics and treatment.

Conclusions
ADH1 can be a cause of idiopathic hypoparathyroidism. Recognition and rational treatment is important for symptom improvement and reducing high potential adverse effects.
Influence of Recovery Time After Warm-up on Vertical Jump Performance in Trained Prepubertal and Postpubertal Male Athletes
Authors: Ferrari Antoine , Baquet Georges , Blazevich Anthony J. , Ratel Sébastien 
Published: March 2023

Abstract
Ferrari, A, Baquet, G, Blazevich, AJ, and Ratel, S. Influence of recovery time after warm-up on vertical jump performance in trained prepubertal and postpubertal male athletes. J Strength Cond Res 37(10): 1985–1992, 2023—The aim of this study was to examine the concurrent effects of maturity status and recovery delay after a standardized dynamic warm-up on vertical jump performance. Thirteen prepubertal boys (9.4 ± 1.1 years) and 12 postpubertal boys (16.6 ± 0.8 years) were tested on squat jump (SJ) and drop jump from 30 cm (DJ30) before and after a standardized, 8-minute, dynamic warm-up, including low-intensity, nonspecific dynamic exercises progressing to maximal, specific exercises, over 6 separate occasions. In each session, subjects jumped at 0, 1.5, 3, 5, 7, or 10 minutes after warm-up in a randomized order. Measurements included SJ height, DJ30 height, ground contact time (GCT), and reactive strength index (RSI) from DJ30. The results revealed no significant recovery time × maturity group interaction effects for SJ height (p = 0.36), DJ30 height (p = 0.45), GCT (p = 0.75), or RSI (p = 0.09), meaning that maturity status did not have a significant effect on changes in vertical jump performance after the warm-up. However, there were significant time effects for SJ height, DJ30 height, and RSI (p < 0.001 for all), with DJ30 height and RSI increasing significantly by 16.9% at 1.5 minutes (p < 0.001) and SJ height increasing significantly by 12.0% until 3 minutes after the warm-up (p < 0.001). To conclude, the standardized dynamic warm-up had beneficial effects on vertical jump performance within the first 3 minutes after completion of the intervention. However, vertical jump performance after the warm-up was not dependent on the children's maturity status.