bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Storage of Yellow Pigment from Halophilic Bacillus clausii J1G-0%B on Antioxidant Activity
Authors: Arum Galuh Dwi , Asy'ari Mukhammad , Mulyani Nies Suci 
Published: March 2023

Oxidative stress is a state of excess free radicals in the body, which results in increased oxidation processes in the body’s cells and causes damage. In previous studies, one way to neutralize this situation was found, namely with halophilic bacteria. Halophilic bacteria can live at a salt content of 2% to 30%. These bacteria can produce various kinds of pigments for self-defense from extreme environments, which function as immunomodulatory compounds and have antioxidant activity. The antioxidant activity of the yellow pigment halophilic bacteria Bacillus clausii J1G-0%B using the DPPH method showed that the effect of light and air on antioxidant activity was 17.88% inhibition in the crude extract and 14.24% inhibition at 1600 ppm. Antioxidant activity decreased by 17.13% under the influence of air, 1.89% under the influence of light, and 28.58% under the influence of air and light. FTIR analysis under the influence of air experienced a decrease in the peak of the CO carbonyl group of 1739.29 cm-1 and an increase in the alkane C-H group of 1369.52 cm-1, while under the influence of light and open conditions, the carbonyl CO group experienced an increase of 1739.50 cm-1 and 1739.46 cm-1 and the increase in alkane C-H groups 1371.41 cm-1 and 1369.53 cm- 1.
ASUPAN VITAMIN D, KALSIUM DAN AKTIVITAS FISIK KAITANNYA DENGAN GANGGUAN SIKLUS MENSTRUASI PADA MAHASISWI
Authors: Mutia Miladia Gita , Putriana Dittasari 
Published: March 2023

Latar Belakang: Masalah kesehatan reproduksi yang sering terjadi salah satunya gangguan siklus menstruasi. Di Indonesia, sebanyak 35,5% mahasiswi yang terdapat di 59 perguruan tinggi mengalami gangguan tersebut. Adapun faktor yang mempengaruhi seperti kurangnya asupan vitamin D, asupan kalsium, dan tingginya aktivitas fisik. Mahasiswa Fakultas Hukum Universitas Muhammadiyah Surakarta memiliki aktivitas yang sangat padat, sehingga dilakukan studi pendahuluan di fakultas tersebut.Tujuan: Penelitian ini bertujuan untuk menganalisis hubungan asupan vitamin D, asupan kalsium, dan aktivitas fisik dengan gangguan siklus menstruasi pada mahasisiwi Fakultas Hukum Universitas Muhammadiyah Surakarta. Metode: Desain penelitian ini adalah observasional dengan pendekatan cross sectional yang melibatkan 73 mahasiswi Fakultas Hukum Universitas Muhammadiyah Surakarta usia 18-19 tahun, yang diambil dengan metode accidental sampling. Data asupan vitamin D dan kalsium diperoleh menggunakan Semi Quantitative Food Frequency Questionnaire (SQ-FFQ) selama satu bulan terakhir, data aktivitas fisik menggunakan International Physical Activity Questionnaire (IPAQ) selama satu minggu terakhir dan data gangguan siklus menstruasi menggunakan kuesioner siklus menstruasi melalui google form. Analisis data pada software SPSS menggunakan uji chi square.Hasil : Sebagian besar responden memiliki asupan vitamin D kurang (94,5%), asupan kalsium kurang (87,7%), aktifitas fisik berat (80,8%) dan gangguan siklus menstruasi (4,1%). Hasil uji analisis chi square tidak terdapat hubungan antara asupan vitamin D (p=0,631), asupan kalsium (p=0,597), dan aktifitas fisik (p=0,389) dengan gangguan siklus menstruasi. Simpulan: Tidak terdapat hubungan asupan vitamin D, asupan kalsium, dan aktivitas fisik dengan gangguan siklus menstruasi (p>0,05). Diharapkan responden dapat meningkatkan asupan vitamin D dan kalsium yang cukup serta memperhatikan aktivitas fisik agar tidak berlebihan
Zbiory funeralne w zasobach Pracowni Dokumentów Życia Społecznego Biblioteki Uniwersyteckiej w Poznaniu – nekrologi i obrazki komemoratywne
Authors: Urbańska Agnieszka 
Published: March 2023

Tekst traktuje o zbiorach funeralnych znajdujących się w zasobach Pracowni Dokumentów Życia Społecznego Biblioteki Uniwersyteckiej w Poznaniu. Należą do nich m.in. nekrologii oraz obrazki komemoratywne. Oba rodzaje tekstów można zróżnicować ze względu na funkcję i cechy zewnętrzne, łączy je natomiast konsytuacyjność w odniesieniu do śmierci konkretnej osoby. Zarówno nekrologi, jak i karty pogrzebowe pozostają ważnym źródłem do badań.
Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi‐stressor military operations
Authors: Varanoske Alyssa N. , Harris Melissa N. , Hebert Callie , Johannsen Neil M. , Heymsfield Steven B. , Greenway Frank L. , Ferrando Arny A. , Rood Jennifer C. , Pasiakos Stefan M. 
Published: March 2023

AbstractPhysical performance decrements observed during multi‐stressor military operations may be attributed, in part, to cellular membrane dysfunction, which is quantifiable using phase angle (PhA) derived from bioelectrical impedance analysis (BIA). Positive relationships between PhA and performance have been previously reported in cross‐sectional studies and following longitudinal exercise training programs, but whether changes in PhA are indicative of acute decrements in performance during military operations is unknown. Data from the Optimizing Performance for Soldiers II study, a clinical trial examining the effects of exogenous testosterone administration on body composition and performance during military stress, was used to evaluate changes in PhA and their associations with physical performance. Recreationally active, healthy males (n = 34; 26.6 ± 4.3 years; 77.9 ± 12.4 kg) were randomized to receive testosterone undecanoate or placebo before a 20‐day simulated military operation, which was followed by a 23‐day recovery period. PhA of the whole‐body (Whole) and legs (Legs) and physical performance were measured before (PRE) and after (POST) the simulated military operation as well as in recovery (REC). Independent of treatment, PhAWhole and PhALegs decreased from PRE to POST (p < 0.001), and PhALegs, but not PhAWhole, remained lower at REC than PRE. PhAWhole at PRE and REC were associated with vertical jump height and Wingate peak power (p < 0.001–0.050), and PhAWhole at PRE was also associated with 3‐RM deadlift mass (p = 0.006). However, PhA at POST and changes in PhA from PRE to POST were not correlated with any performance measure (p > 0.05). Additionally, PhA was not associated with aerobic performance at any timepoint. In conclusion, reduced PhA from PRE to POST provides indirect evidence of cellular membrane disruption. Associations between PhA and strength and power were only evident at PRE and REC, suggesting PhA may be a useful indicator of strength and power, but not aerobic capacity, in non‐stressed conditions, and not a reliable indicator of physical performance during severe physiological stress.
How I Met Your Fans: A Comparative Textual Analysis ofHow I Met Your Motherand Its Reboots
Authors: Kocak Can 
Published: March 2023

AbstractSinceHow I Met Your Mother(HIMYM) ended in 2014 with its ninth season, there have been multiple attempts to create a new series based on a similar premise – one parent telling their kid(s) how they met their other parent.How I Met Your Dad(HIMYD), which was planned to begin in 2014 right after HIMYM’s final, was not picked up by any network, whileHow I Met Your Father(HIMYF), which started airing in 2022, is continuing a successful [Upon its release, the show, whose premiere was watched in 420 K households, held the fifth place on the TV time charts and went on to stay on the list for four more weeks (The Entertainment Strategy Guy).] run, currently in its second season. This article compares the narrative and narration of the first episodes of these three series, including themes, recurring jokes, sound and visual effects, introductions of important characters and the “missing” parent, as well as the use of cameos. By doing this, it aims to delve into the reason behind why one of these reboot attempts was favoured over the other. The answer is provided as the difference between the amount of fan service in HIMYD and HIMYF, with the latter establishing more direct connections with HIMYM. In addition to becoming a rather common tendency by creatives, this article claims that fan service also seems to be used by networks and production companies as a way of ensuring audience engagement.
A study of somatic BRCA variants and their putative effect on protein properties in malignant mesothelioma
Authors: Krishnamurthy Kritika , Oh Kei Shing , Alghamdi Sarah , Sriganeshan Vathany , Poppiti Robert 
Published: March 2023

Abstract

Objectives
The aim of this study is to analyze the prevalence of somatic mutations in BRCA1 and BRCA2 in malignant mesothelioma and their putative impact on protein properties.

Methods
Eighteen cases of malignant mesothelioma were retrieved from the archives and for next generation sequencing analysis of BRCA1 and BRCA2 genes. Variants were analyzed using Ensembl VEP17, Polyphen 2.0 software, SIFT software, MutpredV2, and SWISS-MODEL homology-modeling pipeline server.

Results

BRCA2 variants were found in significantly higher percentage (22%) of cases (p=0.02). Five missense variants were identified. These were p.A2351P, p.T2250A, p.A895V, pG1771D, and p.R2034C. The SIFT scores of all except one were ≥ 0.03. The Polyphen scores of these four alterations were ≤0.899. In case of p.A2315, the SIFT score was 0.01, while the Polyphen 2 score was 0.921. MutPred2 scores were ≤0.180 for all. Loss of intrinsic disorder was predicted (Pr=0.32, p=0.07) for p.R2034C, while gain of intrinsic disorder was predicted for p.A2351P (Pr=0.36, p=0.01) and p.G1771D (Pr=0.34, p=0.02).

Conclusions

BRCA2 somatic variants were identified in 22% cases of malignant mesotheliomas in this study. The variants localize more frequently to the disordered regions of the protein and are predicted to affect the level of disorder.
Process configuration of combined ozonolysis and anaerobic digestion for wastewater treatment
Authors: Otieno Benton , Khune Mervyn , Kabuba John , Osifo Peter 
Published: March 2023

Abstract
Industrial activities and increased human population have made wastewater streams not entirely amenable to conventional treatment methods. Anaerobic digestion (AD) can treat such wastewaters with the advantage of bioresource recovery. However, the presence of solids and recalcitrant compounds in most wastewater streams may affect the AD process. Thus, combining AD with advanced oxidation processes (AOPs) such as ozonolysis is necessary. Ozonolysis can improve the biodegradability of wastewater substrates or eliminate biorecalcitrant pollutants that escape the AD process. This study combined ozonolysis with AD to treat waste activated sludge (WAS) and distillery wastewater (DWW). When applied as a pre-treatment, ozonolysis caused the rigid cell walls in WAS to rupture and solubilised the extracellular polymeric substances (EPS), leading to increased biodegradability. For the DWW, ozonolysis pre-treatment reduced the biorecalcitrant aromatic compounds to simple aliphatic compounds, thereby increasing biodegradability. In the ensuing anaerobic process, the WAS pre-treatment improved TSS and COD reductions and a 230% increase in cumulative biogas production. For the DWW, the ozonolysis pre-treatment did not significantly impact COD reduction or biogas production; however, ozonolysis as a post-treatment removed the color causing biorecalcitrant melanoidins from the anaerobically digested effluent and solubilised the sludge (TSS) washed out from the AD unit. Therefore, the AD-ozonolysis process configuration depends on the substrate being treated. Ozonolysis is best applied pre-AD for WAS treatment and post-AD for DWW.
Niederschwellig, flexibel, digital – Seelsorge auf Instagram
Authors: Lindena Insa Maren 
Published: March 2023

Zusammenfassung
Seelsorge wird schon seit den 1990er Jahren digital per Mail oder Chat angeboten. Seit einigen Jahren gibt es vermehrt auch Seelsorge auf Instagram. Um erste Einblicke zu erhalten, wurde ein Fragebogen entwickelt, der von drei auf Instagram seelsorglich aktiven Pfarrpersonen ausgefüllt und mittels qualitativer Inhaltsanalyse ausgewertet wurde. Die Ergebnisse vermitteln einen Eindruck, wie Seelsorge auf Instagram umgesetzt werden kann und welche Chancen und Herausforderungen dabei entstehen. Sie zeigen, dass die Selbstpräsentation als Pfarrperson sowie die angesprochenen Themen (z. B. Krankheit, Sterben, Beziehungsprobleme, Glaubensfragen) in Posts und Stories Anknüpfungspunkte zur Seelsorge auf Instagram bieten, die v. a. in den Privatnachrichten stattfindet. Die Chance der Instagram-Seelsorge liegt in ihrer Niederschwelligkeit sowie der zeitlichen und örtlichen Flexibilität, die besonders für weibliche, jüngere Personen im Alter von ca. 18 bis 45 Jahren attraktiv sind. Das unvorhersehbare Arbeitsaufkommen und der damit verbundene hohe Zeitaufwand werden wiederum als herausfordernd beschrieben. Auch die Wahrung des Seelsorgegeheimnisses wird aufgrund der Datenschutzprobleme als schwierig wahrgenommen. Doch ein Rückzug aus der Social-Media-Seelsorge scheint trotz der datenschutzrechtlichen Herausforderungen nicht angemessen. Vielmehr besteht die Notwendigkeit, neue Regelungen und technische Möglichkeiten zu entwickeln, um verantwortungsvolle und rechtlich abgesicherte Seelsorge auf Instagram weiterhin zu gewährleisten.
Prevalence and genetic characteristics of fusidic acid resistant Staphylococcus aureus clinical isolates: Emergence of t030 strains carrying fusB in Tehran, Iran
Authors: Goudarzi Mehdi , Seyedjavadi Simasadat , Bagheri Parmida , Dadashi Masoud , Nasiri Mohammad Javad 
Published: March 2023

AbstractThe literature on fusidic acid resistant Staphylococcus aureus strains is scarce in Iran, although the emergence of these strains in health care settings is increasing. This descriptive cross-sectional study was conducted on 68 fusidic acid resistant S. aureus strains to learn about the molecular characteristics and antimicrobial resistance of strains isolated from hospitalized patients. In the present study, the prevalence of resistance to fusidic acid in S. aureus isolates was 15.1%. Fusidic acid resistance determinative factors (fusB, fusC and fusD) were identified by multiplex PCR assay. To detect the existence of fusA and fusE determinants and their mutation status, amplifications and sequencing were performed. Molecular characterization of fusidic acid resistant isolates was investigated by SCCmec and spa typing methods. All strains were MRSA and multi drug resistant. Two (2.9%) and 31 (45.6%) isolates were resistant to vancomycin and mupirocin respectively. The SCCmec type IV was highly prevalent representing 50% followed by types III (51.5%), and SCCmec types II (13.2%). fusB, was the most predominant acquired gene (66.2%) followed by fusC (19.1%), and fusA (14.7%). The mutations in fusA were present in 10 isolates with 5 (50%) having L461K mutation showing fusidic acid MIC values of ≥256 μg ml−1 followed by H457Y (40%), and H457Q (10%) showing fusidic acid MIC values of 128 and 64 μg ml−1 respectively. Isolates were allocated to ten particular t030 (22.1%), t037 (14.6%), t408 (11.8%), t064 (11.8%), t008 (10.3%), t002 (8.8%), t005 (5.9%), t790 (5.9%), t318 (4.4%), and t018 (4.4%) spa types. fusA positive isolates were assigned to particular spa types t002 (60%), and t005 (40%). There may be be a spreading of fusidic acid resistance among MRSA, creating worrying public concern. This research notes the importance of adequate data of local prevalence of FA-resistant MRSA in Iran for taking appropriate measures to treat, control and reduce the incidence of these isolates.
A importância da educação financeira para empreendedores
Authors: Dias Valéria Maria Souza , Figuêredo José Evandro Da Silva 
Published: March 2023

O seguinte estudo mostra que o empreendedorismo é um dos meios de empregabilidade no Brasil, sendo a principal fonte de crescimento da economia. Entretanto, para que as empresas tenham uma boa gestão financeira é necessário que os integrantes tenham conhecimentos básicos sobre educação financeira. Neste contexto, o objetivo deste estudo foi mostrar o quanto é importante a educação financeira para os empreendedores, fazendo um estudo sobre os perfis dos empreendedores brasileiros, como a escolaridade e a faixa etária tem influência em sua educação. Para isso foi utilizada a metodologia de estudos bibliográficos que teve como base a utilização de artigos científicos, livros físicos/virtuais e sites do governo. Essa busca teve como resultado a identificação de vários artigos científicos abordando a temática da educação financeira de várias formas, os quais foram publicados entre os anos de 2016 e 2021, constituindo-se, assim, em uma densa pesquisa de revisão de literatura. Com este estudo percebe-se que a educação financeira é um tema muito discutido na sociedade e tem gerado diversos projetos em políticas públicas e na iniciativa privada. Como também a produção de aplicativos e sistemas inovadores que têm auxiliado novos e futuros empreendedores no sucesso de seu negócio.
Linking process to pattern in community assembly in dry evergreen Afromontane forest of Hararghe highland, Southeast Ethiopia
Authors: Asfaw Zebene , Teshome Wondimu Mengistu , Mohammed Yusuf Muktar 
Published: March 2023

Abstract

Many scholars have attempted to identify the role of deterministic and stochastic processes in community assembly, but there is no consensus on which processes dominate and at what spatial scales they occur. To shed light on this issue, we tested two non-exclusive processes, scale-dependent hypotheses: (i) that limiting similarity dominates on small spatial scales; and (ii) that environmental filtering does so on a large scale. To achieve this, we studied the functional patterns of dry evergreen Afromontane forest communities along elevation gradients in southeastern Ethiopia using floristic and functional trait data from fifty-four 0.04 ha plots. We found evidence of functional overdispersion on small spatial scales, and functional clustering on large spatial scales. The observed clustering pattern, consistent with an environmental filtering process, was most evident when environmental differences between a pair of plots were maximized. To strengthen the link between the observed community functioning pattern and the underlying process of environmental filtering, we demonstrated differences in the topographical factors of the most abundant species found at lower and higher elevations and examined whether their abundance varied over time or changed with time along the elevation. We found (i) that the largest functional differences in the community (observed between lower and upper dry evergreen Afromontane forest assemblages) were primarily the result of strong topographical influence; and (ii) that the abundance of such species varied along the elevation gradient. Variation in stand structure and tree species diversity within the DAF plots shows that topography is among the important drivers of local species distribution and hence the maintenance of tree diversity in dry Afromontane forest.
Our results support the conclusion that environmental filtering at large spatial scales is the primary mechanism for community merging, since functional grouping pattern was associated with species similarities in topographic variation, ultimately leading to changes in species abundances along the gradient. There was also evidence of competitive exclusion at more homogeneous and smaller spatial scales, where plant species compete effectively for resources.
Народники как незамеченный этап на пути к русской модерной политической нации
Authors: Кильдюшов Олег Васильевич 
Published: March 2023

В рецензии обсуждается сборник документальных материалов о народниках XIX века, подготовленный во второй половине 1970-х гг. советским историком М.Я. Гефтером и его единомышленниками в рамках попыток нового прочтения (пред)истории Русской революции, альтернативного официальной историографии. Составитель тома, близкий в то время к диссидентскому и правозащитному движению, концептуально опирался на исследования по общественно-политической истории, проводившиеся в постсталинское время. Ранее он работал в рамках партийно-исторического официоза, от которого дистанцировался к моменту составления «Антологии народников», ставшей для него способом проблематизации соотношения целей и средств (без)ответственного политического действия, цены морального ригоризма революционеров и неготовности авторитарной власти к диалогу с обществом модернизирующейся России. Эта проблематика в контексте незавершенных реформ в позднем СССР позволяла поставить вопрос об идейных истоках и институциональных причинах российских катастроф и тупиков развития уже в веке XX. В начале статьи проводится краткий экскурс в творческую эволюцию самого М.Я. Гефтера, проделавшего большой идейный путь в понимании предмета антологии  – от участника авторского коллектива ортодоксальной истории партии до независимого исследователя, ищущего более сложные модели объяснения исторического процесса в России. Далее реконструируется исследовательская программа, которая легла в основу отбора гетерогенного документального материала. Показан методологически амбициозный план составителя тома, пытавшегося организовать для читателя второй половины XX века не просто погружение в историческую среду второй половины XIX века, но и создать коммуникативное пространство для заочного диалога с акторами другой эпохи. Отмечается близость рамочной идеи издания позднесоветской интеллигентской философии истории, блокирующей сегодня структурную интерпретацию драмы русской модернизации XIX–XX веков. В заключительной части указывается на значительный эвристический потенциал затронутой в антологии топики для реконструкции русского пути к современной политической нации, в рамках которой народники (неожиданно для многих) оказываются первым значимым опытом радикальной демократизации политического в отечественной истории. Предлагается рамочная эвристика, позволяющая при соответствующей смене исследовательской перспективы соотнести русских народников с другими общественно-политическими феноменами модерна в других странах средствами сравнительно-исторической социологии и политической антропологии.
Genetic and semen examination of patients with 46,XX testicular disorder of sex development
Authors: Shtaut M. I. , Sorokina T. M. , Kurilo L. F. , Andreeva M. V. , Oparina N. V. , Polyakov A. V. , Shilova N. V. , Chernykh V. B. 
Published: March 2023

Background. 46,XX male syndrome (XX sex reversal) or 46,ХХ testicular disorder of sex development (DSD) – a genetic disorder that characterized by primary hypogonadism and male infertility because of severe spermatogenesis defects. 46,XX testicular DSD is resulted from unbalanced microstructural sex chromosome abnormalities, mostly X-Y translocations involving SRY gene. Genetic heterogeneity and phenotypic variability, particularly the effect of the genotype on semen parameters in XX sex reversed patients are not sufficiently studied.Aim. Genetic and semen examination in patients with 46,ХХ testicular DSD.Materials and methods. 32 patients with 46,XX testicular DSD and 2 men with mosaicism 46,XX/46,XY were examined. Cytogenetics, molecular genetics and spermatology examination (standard semen analysis and quantitative karyological analysis of immature germ cells) were performed.Results. The presence of the SRY gene was detected in 23 (82.1 %) of 28 patients who underwent a molecular genetic study, and 5 patientswere SRY-negative. Azoospermia and severe oligozoospermiawere diagnosed in 24 (75 %) and 8 (25 %) patients, respectively. Quantitative karyological analysis of immature germ cells allowed to reveal cryptozoospermia in 3 patients with initially diagnosed azoospermia (according to a standard semen analysis). Severe oligozoospermia and cryptozoospermia were mentioned both in some of SRY-positive and SRY-negative patients.Conclusion. 46,XX testicular DSD is characterized by severe degree of spermatogenesis defects (azoospermia and extremely severe oligozoospermia). Small number of germ cells detected in ejaculate in some patients with 46,XX testicular DSD, including SRY-negative individuals, indicates partial preservation ofspermatogenesisin the absence of Y chromosome genes.