bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative effect of intraurethral clobetasol and tacrolimus in lichen sclerosus-associated urethral stricture disease
Authors: Choudhury Sunirmal , Khare Eeshansh , Pal Dilip Kumar 
Published: April 2023

Background:
Management of urethral stricture related to lichen sclerosus (LS) is now gradually changing from surgical to nonsurgical due to availability of anti-inflammatory agents such as corticosteroids and calcineurin inhibitors. We determined the clinical impact of these agents in such patients on outpatient department basis in terms of improvement in symptoms on International Prostate Symptom Score (IPSS), external skin appearance, and maximum urinary flow rate (Qmax).

Materials and Methods:
Eighty patients of meatal stenosis and penile urethral stricture with histopathologically proven LS were divided into two groups, and clinical and predetermined parameters such as Qmax, IPSS, and changes in external appearance were compared between these groups after 3 months of topical and intraurethral application of clobetasol and tacrolimus with self-calibration.

Results:
A significant intragroup difference was noted in IPSS (P < 0.001) as well as Qmax (P < 0.001); postintervention intergroup difference in IPSS was not significant (P = 0.94) and however postintervention intergroup difference in Qmax was significant in favor of clobetasol (P = 0.007). A significantly increased number of additional procedures were done in the group receiving intraurethral tacrolimus (P = 0.0473) with significantly less number of skin complication in the group with topically applied clobetasol (P = 0.003).

Conclusion:
Though both clobetasol and tacrolimus, improved symptom score, Qmax and local external appearance yet topical and intra-urethral clobetasol application via urethral self calibration seems to be better option for lichen sclerosus related urethral stricture in terms cost and local complications.
Prospective evaluation of an intraoperative urodynamic stress test predicting urinary incontinence after robot-assisted laparoscopic radical prostatectomy
Authors: Mohr Mirjam Naomi , Uhlig Annemarie , Strauß Arne , Leitsmann Conrad , Ahyai Sascha A , Trojan Lutz , Reichert Mathias 
Published: April 2023

Introduction:
Multiple factors influence postprostatectomy incontinence (PPI). This study evaluates the association between an intraoperative urodynamic stress test (IST) with PPI.

Materials and Methods:
This is an observational, single-center, prospective evaluation of 109 robot-assisted laparoscopic radical prostatectomies (RALPs) performed between July 2020 and March 2021. All patients underwent an intraoperative urodynamic stress test (IST) in which the bladder is filled up to an intravesical pressure of 40 cm H2O to evaluate whether the rhabdomyosphincter is capable of withstanding the pressure and ensure continence. Early PPI was evaluated using a standardized 1-h pad test performed the day after removal of the urinary catheter. The association of IST and PPI was evaluated using univariate and multivariable logistic regression models.

Results:
Nearly 76.6% of the patients showed no urine loss during the IST (“sufficient” population group). There was no significant correlation between this group and PPI after catheter removal (P = 0.5). Subgroup analyses of the “sufficient” patient population showed a 3.1 higher risk of PPI when no nerve sparing was performed (95% confidence interval: 1.05–9.70, P = 0.045).

Conclusion:
A sufficient IST, as a surrogate variable for a fully obtained rhabdomyosphincter, has no significant predictive value on its own but seems to be the optimal prerequisite for continence, since the data shows that the lack of neurovascular supply required for a functioning sphincter leads up to a 3.1 times higher risk for PPI.
P53 and survivin expression in renal cell carcinoma
Authors: Radovanović Milan , Petrović Miloš , Šantrić Veljko , Milojević Bogomir , Zubelić Aleksa , Isaković Aleksandra 
Published: April 2023

Objective:
Mutation of p53 is detected in more than 50% of human cancers, expression of p53 has a potential prognostic value in patients with renal cell carcinoma (RCC). Survivin is a member of the inhibitor of apoptosis protein family, its overexpression is observed in many malignancies, including RCC. The aim of the study was to estimate a correlation between survivin and p53 expression in tumor samples and the histologic type of a tumor, tumor stage, tumor grade, and survival of patients.

Materials and Methods:
Tumor samples were collected from surgical specimens of 90 patients who underwent radical or partial nephrectomy for RCC between November 2017 and July 2020. Tumors were staged according to the UICC (The Union for International Cancer Control) TNM classification system and histopathologically graded according to Fuhrman nuclear grade system. Histopathological diagnosis was confirmed with standard light microscopic evaluation, using hematoxylin and eosin staining and standard p53 and survivin antibodies.

Results:
Positive p53 staining was observed in 36.7% of tumor specimens and 24.4% were survivin positive. There was a statistically significant correlation between p53 or survivin expression and histologic subtype of clear cell RCC as well as Type I and II of papillary RCC. There was a statistically significant correlation between p53 expression and tumor size, stage, and grade. The p53 or survivin expression was related to lower overall survival.

Conclusion:
The results of this study suggest that p53 overexpression and survivin positivity in RCC patients could be associated with poor prognosis. Thus, these proteins could be used as prognostic markers in RCC.
Comparative analysis of partial versus radical nephrectomy for renal cell carcinoma
Authors: Hakam Nizar , Heidar Nassib Abou , El-Asmar Jose , Khauli Mark , Degheili Jad , Al-Moussawy Mouhamad , Nasr Rami , El-Hajj Albert , Wazzan Wassim , Bulbul Muhammad , Khauli Raja B 
Published: April 2023

Objectives:
Over the past 20 years, the utility of partial nephrectomy (PN), compared to radical nephrectomy (RN), for the management of localized renal cell carcinoma (RCC) has progressively increased, particularly for larger and more complex masses. We sought to compare the recurrence-free survival (RFS) outcomes of PN versus RN in a single-institution cohort.

Methods:
Between 2002 and 2017, 228 patients underwent RN or PN for lcT1a-T2b, N0M0 RCC at a single tertiary referral center, performed by five surgeons. The clinical end point result was (local or distant) RFS. Univariate and multivariate (cox regression) models were used to evaluate the association between type of surgery (PN vs. RN) and RFS, in the overall cohort and in a subgroup of patients with cT1b.

Results:
The median age was 59 (interquartile range [IQR] 48–66), and the median tumor size was 4.5 cm (IQR 3–7). There were 128 PN and 100 RN. Over a median follow-up of 4.2 years (IQR 2.2–6.9), the Kaplan–Meier analysis showed no significant RFS difference between PN and RN (logrank P = 0.53). On multivariate analysis, pathologic stage ≥T2a, Fuhrman Grade ≥3, and chromophobe histology were associated with a worse RFS. PN was not significantly associated with diminished RFS (Hazard ratio [HR] 1.78, 95% confidence interval [CI] 0.74–4.3, P = 0.199) in the overall cohort compared to RN. However, in the cT1b subgroup, PN was associated with a significant increase in recurrence compared to RN (HR = 12.4, 95% CI 1.45–133.4, P = 0.038).

Conclusions:
Our institutional data highlight the possibility of compromise in RFS for clinically localized RCC treated with PN compared to RN, particularly for larger and more complex masses. These data raise concern, especially in light of the nonproven association of survival benefit of PN over RN, warranting future randomized prospective studies for further evaluation.
Computational Modeling of the Flow and Heat Transfer in an Internal Combustion Engine-Relevant Cooling Channel
Authors: Wegt Sebastian , Bopp Maximilian , Krüger Louis , Klink Artur , Reitz Ruediger , Hussong Jeanette , Jakirlic Suad 
Published: April 2023

<div class="section abstract"><div class="htmlview paragraph">The “Water Spider Geometry” (WSG) configuration, representing a newly developed reference test sample designed to suitably investigate the flow and heat transfer processes relevant to cooling systems of internal combustion engines, was computationally investigated by applying a recently proposed Reynolds Stress model called the “Elliptic-Blending Model” (EBM). The WSG configuration resembles a specifically configured pipe geometry that appropriately mimics the flow phenomena encountered in cooling channels of realistic internal combustion engine, such as flow impingement and bifurcation, multiple deflections and flow confluence. The reference database, consisting of mean flow and turbulence fields, was provided by a Large-Eddy Simulation. The EBM formulation has been intensively validated by calculating numerous isothermal wall-bounded flows. The present work focuses on testing the EBM predictive performances under the conditions of non-isothermal flow scenarios. Before proceeding to the WSG configuration, the EBM is pre-validated by computing a jet discharging from a channel-like nozzle and impinging perpendicularly onto a heated wall. The results obtained follow closely the data of the reference Direct Numerical Simulation, also with respect to the predicted second peak at the Nusselt number distribution in terms of different nozzle-to-wall spacing. The EBM-predicted mean velocity field and associated global flow characteristics within the WSG configuration agree well with the results of the reference Large-Eddy Simulation, in contrast to those obtained by the widely used <i>k</i> − <i>ω</i>-SST model, which has been applied in addition. Different treatments of the near-wall region were also used, including integration to the wall and the universal wall-functions. The computationally obtained temperature field evaluated at the WSG walls reveals the hot spot location within a straight pipe segment situated between two deflections, closer to the upstream one, coinciding with the experimentally detected region of most severe degradation caused by intense heating.</div></div>
Current and Torque Harmonics Analysis of Dual Three-Phase Permanent-Magnet Synchronous Machines with Arbitrary Phase Shift Based on Model-in-the-Loop
Authors: Shi Bufan , Andert Jakob , Wang Haoran 
Published: April 2023

<div class="section abstract"><div class="htmlview paragraph">Dual three-phase permanent magnet synchronous machines (DTP-PMSM) are becoming increasingly popular in automotive electric powertrains due to their reduced phase currents and fault tolerance. The unique advantages of specific phase shift angles (such as 0°, 30°, 60°, etc.) between dual three-phase windings have been extensively studied. In this paper, the current and torque harmonics induced by the inverter are analyzed and the corresponding harmonics suppression strategy are proposed for a DTP-PMSM with different phase shift angles. In addition, this paper analyzes the effect of the phase shift angle between the dual three-phase windings on the torque ripple and phase losses, and proposes a novel optimal phase shift angle 80°. First, a mathematical vector space decomposition (VSD) model for a DTP-PMSM with arbitrary phase shift angles is derived. Second, a theoretical derivation of the torque harmonics based on phase current and induced electromotive force harmonics is carried out, and the effects of current and rotor flux-induced electromotive force harmonics of (6<i>k</i> ± 1)<i><sup>th</sup></i>orders on torque ripple are obtained. For torque ripple suppression, the mapping of the phase current harmonics in VSD synchronous coordinate system with arbitrary phase shift angles is derived. Furthermore, a model-in-the-loop (MiL) simulation is set up using a mathematical model of an ideal electrical machine and a non-ideal 6-phase inverter model implemented in PLECS, and the VSD-based field-oriented control algorithm implemented in Matlab/Simulink. The simulation results for different phase shift angles show that the dq current, dqz current, dc-link current and torque harmonics vary periodically with the phase shift angle for (6<i>k</i>)<i><sup>th</sup></i> orders. In addition, the proposed 80° configuration has relatively lower losses and torque ripple after weighing both aspects over all the phase shifts. Finally, the harmonics suppression method is validated in the MiL.</div></div>
أثر الدخل القومي المتاح والاستثمار الاجمالي على الاستهلاك الكلي في اليمن دراسة قياسية باستخدام منهج ARDL خلال الفترة (1991-2017م)
Authors: Alsaqqaf Yasmin Mohammed Alawi Ali 
Published: April 2023

هدفت هذه الدراسة التعرف إلى تأثير الدخل القومي المتاح والاستثمار الاجمالي على الاستهلاك الكلي في اليمن خلال الفترة (1991- 2017م)، اعتمدت هذه الدراسة على المنهج الوصفي التحليلي والمنهج الكمي القياسي، باستخدام أداة حديثة متمثلة في نموذج الانحدار الذاتي للإبطاء الزمني الموزع (ARDL) لتقدير العلاقة في المدى القصير والطويل بين متغيرات الدراسة، باستخدام بيانات الاقتصاد اليمني الصادرة عن الجهاز المركزي للإحصاء، وقد توصلت الدراسة الى النتائج الآتية: -

تبين اختبارات الاستقرار باستخدام جذر الوحدة على أن المتغيرات غير مستقرة في المستوى العام (Level)، إلا أنها مستقرة في الفروق الأولى، كما أوضحت نتيجة اختبار الحدود للتكامل المشترك وجود علاقة توازنية طويلة الأجل تتجه من المتغيرات المستقلة (الدخل القومي المتاح والاستثمار الاجمالي) الى المتغير التابع (الاستهلاك الكلي).
أفضل نموذج وفق معيار (AIC) لمحددات الاستهلاك الكلي هو (1 ,2 ,4)ARDL
الدخل القومي المتاح والاستثمار الاجمالي تفسر حوالي 99.9% من التغير في الاستهلاك الكلي خلال فترة الدراسة.
أغلب المعلمات معنوية في الأجل القصير، وكذلك ثبوت معنوية بعض المعلمات في الأجل الطويل.
بينت نتائج تحليل نموذج تصحيح الخطأ وجود الية لتصحيح الخطأ في النموذج، وأن دالة الاستهلاك الكلي الاجمالي في الأجل القصير تتجه للتوازن في الأجل الطويل، وأن معلمة تصحيح الخطأ سالبة ومعنوية.
خلو النموذج المقدر من مشاكل القياس الاقتصادي المتمثلة في الارتباط الذاتي وعدم ثبات تباين حد الخطأ، أظهرت نتائج اختبارات استقرار المقدرات أن مقدرات النموذج مستقرة.
Pengaruh Tingkat Pendidikan dan Pelatihan terhadap Prestasi Kerja Karyawan Hotel Mauve Palembang
Authors: Sali Yopi Okta , Halin Hamid , Handayani Susi 
Published: April 2023

The intention of this study is to analyze the effect of the level of education and training on the work performance of hotel employees Mauve Palembang. The sample was collected by the saturated sample technique. Data of 43 respondents was collected through documentation and questionnaires. This study implements multiple linear regression method to analyze the data. The results of the investigation prove that in part, both the level of education and training have a significant positive effect on employee performance. This fact is useful for Hotel Mauve Palembang. To improve employee performance, the company must consider the level of education and training factors together.
Review And Analysis On Hybrid Control Of Fault Ride Through And Transient Stability Of Vsc-Hvdc
Authors: Karunakar  
Published: April 2023

A steady DC-Link Voltage, a CV voltage control and a reactive power control on the basis of the previous reviewers' analysis are the goals of the VSC-HVDC connecting controller. In order to achieve these objectives, the appropriate controller is required at both VSC-HVDC terminals. This paper presents a non-linear control approach to improve the VSC-HVDC relationship's control robustness. A sliding mode control (SMC) and an integrated proportional control (PI) were used for the configuration of a hybrid controller. The hybrid controller will provide mathematical simulation. This hybrid driver provides malfunction driving and the transient reliability of the VSC-HVDC link. This paper presents a non-linear approach to control to improve the robustness of the VSC-HVDC controller. The hybrid controller configuration is a control of the sliding mode (SMC) and an integrated proportional control (PI) for a hybrid controller design. Fault ride the stability of this hybrid control unit is provided through and transient VSC-HVDC links. MATLAB and Simulink simulate the hybrid controller and increases the performance of the controller. The simulation induces a symmetrical grid-side malfunction to maintain transient stability.
Low-Level Laser Treatment for Lower Back Pain
Authors: Madakadze Candice , Bailey Sharon 
Published: April 2023

The CADTH Horizon Scanning Service identifies emerging health technologies that may be of potential interest to health care decision-makers in Canada.
Chronic pain, including chronic low back pain, challenges many aspects of people's lives, including social, physical, mental, and professional. Approximately 80% of adults will be affected by chronic lower back pain at least once in their lifetime and seek out multiple treatment options, including drug treatments, psychological treatments, and physical therapies.
This Horizon Scan summarizes available information regarding an emerging technology, the Erchonia FX 635 low-level laser system, for the treatment of chronic low back pain.
The effectiveness of Turmeric gel in the healing of donor site for Free Gingival Graft
Authors: Alasfar Zuhir , Saymeh Rowaida , Khazem Mays 
Published: April 2023

BACKGROUND: Preparation of turmeric extract gel with a concentration of 10% and comparing it with non-eugenol gingival dressing (Coe-PakTM) in the healing and re-epithelialization of palatal donor site after free gingival graft, and reduction of postoperative pain.MATERIALS AND METHODS: This study was conducted on twenty-two patients with lack of attached gingival tissue for various reasons and received soft tissue augmentation via free gingival grafts. Participants were randomly divided into two equal groups: group I (test) was treated with 10% turmeric gel while group II (control) was treated with (Coe-PakTM). Both pain level index which assessed by using the Visual Analogue Scale (VAS) and Analgesic consumption index were recorded for 7 days after surgery. The healing index, the color match index, and the re-epithelialization index were assessed on days 7, 14, 21, and 28. Finally, wound size index was measured via periodontal Probe at baseline and days 7, 14, 21, 28, and after 2 months.RESULTS: Group I showed significant pain reduction measured by VAS and analgesic consumption on day 3, 4, 5, 6, 7 (p<0.05) with no significant difference on the first two days (p>0.05). Group I demonstrated significant acceleration in the initial healing process during the 1st week (p=0.002) and 2nd week (p=0.01) with no significant difference between both groups in the 3rd and 4th weeks (p>0.05). Group I showed statistically higher VAS for the color match on day 7, 14, 21, and 28. No statistical difference was noted between the groups after two months. There was no statistical difference between groups I and II in the re-epithelialization and wound size index at any of the follow-up periods (p>0.05).CONCLUSION: 10% turmeric extract gel showed relief of post-operative pain, acceleration of the healing process, and better outcomes in terms of the color match for the palatal wound after free gingival grafting procedure comparing to the Coe-PakTM periodontal dressing.KEYWORDS: Curcumin; Free gingival graft; periodontal dressing; donor site
HUBUNGAN PENGETAHUAN DAN PARITAS IBU DENGAN PENGGUNAAN KB SUNTIK DI PMB ZUNIAWATI PALEMBANG TAHUN 2021
Authors: Nurbaity  , Dona Trisundari  
Published: April 2023

Dari data WHO didapatkan sebanyak jumlah pengguna kontrasepsi di dunia yaitu sebanyak 159 juta pengguna KB IUD, 23 juta pengguna KB Implant, 74 juta pengguna KB suntik, 150 juta pengguna KB Pil. Keluarga berencana salah satu pelayanan kesehatan yang paling dasar dan utama bagi wanita. Penggunaan KB suntik dapat disebabkan oleh beberapa faktor diantaranya pengetahuan dan paritas ibu. Metode kontrasepsi suntik merupakan metode kontrasepsi yang paling banyak digunakan. Tujuan penelitian untuk mengetahui hubungan hubungan pengetahuan dan paritas ibu dengan penggunaan KB suntik di PMB Zuniawati Palembang tahun 2021. Metode penelitian menggunakan metode cross sectional. Populasi pada penelitian ini adalah semua akseptor KB suntik 1 bulan, 2 bulan dan 3 bulan yang berkunjung ke PMB Zuniawati Palembang saat dilakukan penelitian dengan jumlah sampel sebanyak 35 responden. Hasil penelitian didapatkan distribusi frekuensi responden sebagian besar menggunakan alat kontrasepsi suntik 3 bulan sebanyak 16 responden (45,7%), sebagian besar berpengetahuan baik sebanyak 23 responden (65,7%), sebagian besar multipara sebanyak 20 responden (57,1%). Hasil uji statistik didapatkn ada hubungan yang bermakna antara pengetahuan (p value = 0,039) dan paritas ibu (p value = 0,045) dengan penggunaan KB suntik di PMB Zuniawati Palembang tahun 2021 dengan nilai. Saran diharapkan tenaga kesehatan dapat lebih meningkatkan pemberian konseling kepada akseptor KB untuk menambah pengetahuan akseptor seputar alat kontrasepsi yang digunakan khususnya alat kontrasepsi suntik.
Peranan Gaya Hidup dan Pola Makan yang Sehat Serta Tingkat Kecukupan Gizi
Authors: Rahayu Cucu , Wardani Rizky Kusuma , Citerawati Yetti Wira , Nurkarsa Aldo Hermaya Aditia 
Published: April 2023

Abstract
This study conducted a review of the interaction between dietary patterns, food nutrition, and lifestyle in relation to the assessment of health status. Dietary patterns have the advantage of considering any correlations that may exist between foods or food groups, but also between nutrients. The purpose of this research is to carry out an alternative and complementary approach in analyzing the relationship between nutrition and a healthy lifestyle. To determine dietary patterns, an index/score can be used to assess the suitability of a diet with nutritional guidelines or a predetermined pattern (a priori approach). The method used is a qualitative approach based on exploratory data (a posteriori): cluster analysis and factor analysis. Dietary patterns can vary according to gender, socio-economic status, ethnicity, culture and other factors, but more than that, the relationship between these three things can vary depending on the different relationships between these factors. Diet patterns influence health synergistically or even together with other lifestyle factors, and therefore we can refer to lifestyle patterns.
HUBUNGAN USIA DAN KETUBAN PECAH DINI DENGAN KEJADIAN PARTUS LAMA DI RUMAH SAKIT RADEN MATTAHER PROVINSI JAMBI
Authors: Riya Rosa , Rosinar Rosinar 
Published: April 2023

Partus lama Persalinan yang terjadi lebih dari 24 jam pada primi dan lebih dari 18 jam pada multigravida. Persalinan lama yang disertai komplikasi dan janin. Tujuan penelitian ini adalah untuk menggetahui adanya hubungan usia dan ketuban pecah dini dengan kejadian partus lama di RSUD Raden Mattaher Provinsi Jambi tahun 2018. Hasil uji statistik chi-square p-value =0,000 (p<0,05) disimpulkan bahwa ada hubungan usia dengan kejadian partus lama dengan nilai OR 7,629 (3,689-15,776). Sedangkan ketuban pecah dini (> 6 jam) mengalami partus lama sebanyak 81 (54,0%) dan ketuban pecah dini (<6 jam ) sebanyak 69 (46,0%) responden. Dari hasil uji chi-square di peroleh nilai p-valeu 0,000 (p<0,05) disimpulkan bahwa ada hubungan ketuban pecah dini dengan kejadian partus lama dengan nilai OR 4,571 (2,292-9,116). Kesimpulan penelitian ini adalah terdapat hubungan usia dan ketuban pecah dini dengan kejadian partus lama.