bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Descriptive Study of Needlestick or Sharps Injuries in National Healthcare Group Polyclinics Dental Clinics in Singapore From 2014-2020
Authors: Wong Vivian , Chao Priscilla , Lee Sabrina , Lee Eng , Lang Lily , Koh Holy , Low Kenneth 
Published: August 2023

Abstract
Introduction
All dental staff face risk of needlestick or sharps injuries (NSI). Many instruments used in dental procedures are sharp.
Aim
This study aims to identify factors associated with NSI among dental staff by evaluating circumstances and staff designation involved. This allows targeted intervention to prevent/reduce NSI.
Methods
NSIs were reported through an electronic incident reporting system from 2014 to 2020. Reports included nature and extent involved. Statistical analysis was carried out to find associations between factors such as injury site, type of instrument and staff designation.
Results
A total of 63 NSIs were included in this study. The type of device was found to be significantly associated with staff designation (p=0.04, p<0.05) with significantly more dental burs causing injury in dentists and more injuries caused by ‘other instruments’ in health attendants (p= 0.0083). Staff designation was significantly associated with the instance where sharp incident occurred (p <0.001). Dentists and dental assistants were more likely to sustain injuries during a dental procedure than before procedure and after procedure (p=0.0167).
Conclusions
Dentists are prone to NSI due to the use of dental burs and needles. Targeted interventions might help prevent NSIs.
Granular Vortex Spin-Torque Nano Oscillator for Reservoir Computing
Authors: Shreya Sonal , Jenkins Alex , Rezaeiyan Yasser , Li Ren , Bohnert Tim , Ferreira Ricardo , Moradi Farshad , Farkhani Hooman 
Published: August 2023

Abstract
In this paper, we investigate the granularity in the free layer of the magnetic tunnel junctions (MTJ) and its potential to function as a reservoir for reservoir computing where grains act as oscillatory neurons while the device is in the vortex state. The input of the reservoir is applied in the form of a magnetic field which can pin the vortex core into different grains of the device in the magnetic vortex state. The oscillation frequency and MTJ resistance vary across different grains in a non-linear fashion making them great candidates to be served as the reservoir's outputs for classification objectives. Hence, we propose an experimentally validated area-efficient single granular vortex spin-torque nano oscillator (GV-STNO) device in which pinning sites work as random reservoirs that can emulate neuronal functions. We harness the nonlinear oscillation frequency and resistance exhibited by the vortex core granular pinning of the GV-STNO reservoir computing system to demonstrate waveform classification.
An assessment of Inside surface temperature (Tin) upon introduction of green facade of varying Leaf Area Index (LAI), through mathematical model
Authors: Mitra Sreemoyee , Das Vinay Mohan 
Published: August 2023

Abstract
Increasing urbanization has led to the deterioration of green space, raising concerns about the environmental impact and quality of urban living. In response to these challenges, the concept of green façades has emerged as a promising solution, particularly in enhancing the energy efficiency of built structures. This study aims to explore the thermal behavior of opaque constructions when integrated with vegetation during high radiation phases, focusing on the geographical location of Delhi. The mathematical model proposed by Susorova is employed to investigate the impact of foliage and façade orientation on the inside surface temperature (Tin) of walls. The independent factors considered are leaf area index (LAI) and incoming radiation, as they significantly influence thermal performance. Specifically, the study reveals that the effect of LAI varies during direct and diffused radiation phases. For eastern and western façades, an LAI of 1 or 2 yields the most significant reduction in Tin during high radiation phases, whereas the northern façade benefits from an LAI of 4 due to its exposure to diffused radiation. The southern façade exhibits a similar pattern as western and eastern façades, but with minimal variation in temperature magnitude. Additionally, the study delves into the contribution of short-wave radiation, long-wave radiation, and convective heat/gain in the heat balance equation, studying their influence with varying LAI. The findings of this research provide valuable insights for designing green façades on vertical structures in similar climatic conditions to optimize passive cooling and overall energy efficiency.
Phylogenetic relationship between Contracaecum spp. (Nematoda, Anisakidae) parasitizing cormorants (Aves, Phalacrocoracidae) from Argentina
Authors: Garbin Lucas Emiliano , Servián Andrea , Fuentes Lautaro , Morgenthaler Annick , Millones Ana , Fuchs Daniela , Diaz Julia Inés , Navone Graciela Teresa 
Published: August 2023

Abstract

Anisakidae nematodes have a wide host and geographic distribution. Species of the genus Contracaecum parasitize aquatic organisms such as piscivorous birds and mammals as their definitive hosts. Several Contracaecum species have been reported parasitizing Phalacrocoracidae in South America. The aim of this work is to highlight phylogenetic relationships between Contracaecum species parasitizing shags based on both molecular markers and the papillae pattern arrangement on the male tail. Some Contracaecum specimens parasitizing Red-legged cormorants from the Ría Deseado (RD), and other nematodes parasitizing eight dead Neotropic cormorants from San Miguel del Monte lagoon (SMML), Argentina, were collected and analyzed. An integrative analysis allowed us to recognize Contracaecum chubutensis parasitizing Phalacrocorax gaimardi, and Contracaecum australe parasitic in Phalacrocorax brasilianus. According to obtained mtDNAcox2, ITS1, ITS2, and SSrRNA isolates, Contracaecum sp. parasitizing P. gaimardi matched with the previously reported C. chubutensis parasitizing P. atriceps from Bahía Bustamante, Chubut province. Likewise, Contracaecum sp. isolates parasitizing P. brasilianus clustered with C. australe from Chile. Besides, the papillae pattern arrangement of the male tail allowed us to understand the interspecific and genetic relationships between the Contracaecum species. The analysis confirm that C. chubutensis specimens parasitizing P. gaimardi from RD represent a new host and the southernmost record for the species. Whereas, those C. australe specimens parasitizing P. brasilianus from SMML provide a new geographical record for the species and the extension of its distribution range. Present results also confirm the inland and marine distribution of C. australe and C. chubutensis, respectively.
In Situ Graphene Synthesis Study in Inductively Coupled Radiofrequency Thermal Plasma Reactor using Methane Precursor
Authors: Mahmoud Reem , Gitzhofer François , Blanchard Jasmin , Abatzoglou Nicolas 
Published: August 2023

Abstract
While numerous studies are available on methane pyrolysis chemical kinetics and the effect of plasma parameters on graphene synthesis, a comprehensive understanding of the formation mechanism remains elusive without in situ analysis. This study aims to utilize a sampling probe for the first time to collect graphene locally on transmission electron microscopy grids and perform a localized sampling and analysis of the gas composition (during graphene synthesis) using mass spectrometry. This technique provides a 3D tracking of methane pyrolysis in radiofrequency inductively coupled thermal plasma reactor for graphene production. Response surface methodology based on central composite design is employed to obtain a 3D visualization of the synthesis process. Quadratic and cubic models are developed, followed by comprehensive analysis of variance. A comparison of the gas-phase chemistry resulting from the in situ measurements with thermodynamic equilibrium calculations reveals that the process is controlled by thermochemical kinetics. H2, C2H2, C2H4, C3H6, and C6H6, as well as residual CH4, are the main hydrocarbons found in the graphene nucleation zone. The primary pathway for methane pyrolysis and graphene formation in RF plasma is through H2 and C2 hydrocarbons, while graphene nucleation and growth reactions are terminated 350 mm from the plasma torch nozzle exit. Morphology, quality, mean particle size, and the number of layers of the produced graphene samples, locally collected at different locations by 3D axisymmetric probe scanning, were investigated using TEM, high-resolution TEM imaging, and Raman analysis. The gathered information is highly valuable for plasma reactor design.
Social Welfare Receipt, Race, and Participatory Behavior
Authors: Davis Brandon 
Published: August 2023

Abstract
This paper examines how the resources associated with the Temporary Assistance for Needy Families program, the Supplemental Nutrition Assistance Program, and the Unemployment Insurance program affect political participation. The research on policy feedback on mass publics has produced greater results relative to research on feedback and political participation. However, prior research has not disaggregated resource feedback effects thoroughly enough to decipher whether the monetary resources provided by a social welfare program are independent of the effects of the duration of receipt nor have they disaggregated the effects by race to estimate the racialized feedback effects. This is crucial because the primary questions surrounding the development of social welfare programs are: who should get it, how much they should get, and how long they should get it for. Research has also found that social welfare programs can produce disparate resource feedback effects, both encouraging and discouraging participatory behavior. To answer these questions, I utilize the 1997 National Longitudinal Survey of Youth. I incorporate three comprehensive measures of social welfare receipt which allow the estimation of the effects over time. I find that the amount of aid received, and the duration of receipt are both significant factors in shaping participatory behavior but depending on the program I find heterogeneous effects. The disparate effects persist across social welfare programs and race.
Residential proximity to metal emitting industries and toenail metal concentration in the US Gulf States
Authors: Lin Joyce JY , Werder Emily , Lawrence Kaitlyn G , II W. Braxton Jackson , Sandler Dale P , Dickerson Aisha S , Engel Lawrence S , Rule Ana M 
Published: August 2023

Abstract
Objective: The US Gulf region is heavily reliant on metal-emitting petrochemical and manufacturing industries. We characterized the effect of residential proximity to metal-emitting sites and metal body burden in Gulf states residents with particular attention to potential differential exposure burden by race.
Methods: We measured toenail concentrations of arsenic, chromium, lead, manganese, mercury, and selenium using inductively coupled plasma mass spectrometry in 413 non-smoking men from the Gulf Long-term Follow-Up Study. Point sources of industrial metal emissions were identified using the US EPA’s National Emissions Inventory (NEI) database and geocoded to participant residential addresses. For each metal, we assessed associations of toenail metal concentrations with the inverse-distance weighted number of emissions sites and volume of air-metal emissions within 30 km radial buffers of participant residences using multivariable linear regression. Results were stratified by race.
Results: Compared to self-identified Non-Hispanic (NH) White participants, NH Black participants lived closer to NEI sites but had 23-70% lower toenail metal concentrations adjusting for other personal/behavioral factors. Residential proximity to lead-emitting NEI sites was positively associated with toenail Pb concentration while proximity to mercury-emitting NEI sites was inversely associated with toenail Hg concentration. Findings for lead were significantly attenuated after adjustment for neighborhood-level socioeconomic factors.
Conclusion: Residential proximity to lead-emitting NEI sites in the US Gulf region is associated with a higher body burden of lead. However, this relationship may be driven in part by non-NEI factors related to residence in industry-adjacent neighborhoods.
Acacia nodule-associated bacteria induced plant growth promotion and soil N availability
Authors: Yu Lina , You Fang , Wu Songlin , Lu Zhaohua , Huang Longbin 
Published: August 2023

Abstract
Background and aims
Legume-rhizobia symbiotic N fixing potentially contribute to restoring fertility in mined land during rehabilitation efforts. Particularly, Acacia spp. stands out as an important legume of native vegetation, while their symbiotic relationship development and impacts on soil rehabilitation have not been fully understood.
Methods
In our glasshouse experiment, symbiosis relationship between three Acacia species (A. holosericea, A. ampliceps, and A. auriculiformis) and bacterial inoculum (Acacia nodule-associated bacteria (NAB), Bradyrhizobium diazoefficient CB1809, and Rhizobium leguminosarum bv viciae RLV248) and the effects of seedling ages on nodule formation were investigated. Additionally, the symbiotic nodule development and their the impacts on plant growth, plant N acquisition, and soil N availability were compared.
Results
The results revealed all three Acacia seedlings successfully formed nodules, with each displaying distinct morphology. Seedlings at 8 weeks demonstrated higher efficacy to form nodules than the those of 12 and 16 weeks old. A. auriculiformis is mostly effective to form nodules with all bacterial inoculums, especially with NAB. Rhizobium in A. auriculiformis nodules are dominated by Bradyrhizobium. Mesorhizobium is predominant in A. ampliceps nodules. Both Bradyrhizobium and Mesorhizobium are highly abundant in the nodules of A. holosericea. Symbiotic nodule development also induced plant growth promotion and N acquisition, with CB1809 the mostly effective. Notably, NAB inoculation could significantly enhanced soil N availability in addition to promoting plant growth.
Conclusion
These findings underscore the significance of Acacia-NAB symbiosis as a beneficial strategy to boost plant growth, increase soil N availability, and potentially aid in ecological rehabilitation endeavors.
Regulatory mechanism for the human glioblastoma cell-specific expression of the human GD1c/GT1a/GQ1b synthase (hST8Sia V) gene
Authors: An So-Young , Lee Ji-Won , Kim Hee-Do , Kim Kyoung-Sook , Cho Jong-Hyun , Kim Cheorl-Ho , Lee Young-Choon 
Published: August 2023

Abstract
In this study we observed that human GD1c/GT1a/GQ1b synthase (hST8Sia V) is particularly expressed in human glioblastoma cells. To address the mechanism regulating human glioblastoma-specific gene expression of the hST8Sia V, after the transcription start site (TSS) was identified by the 5’-rapid amplification of cDNA end with total RNA from human glioblastoma U87MG cells, the 5’-flanking region (2.5 kb) of the hST8Sia V gene was isolated and its promoter activity was examined. By luciferase reporter assay, this 5’-flanking region revealed strong promoter activity in only U-87MG cells, but not in other tissue-derived cancer cells. 5’-deletion mutant analysis showed that the region from -1140 to -494 is crucial for transcription of the hST8Sia V gene in U87MG cells. This region contains the activator protein-1 (AP-1) binding site, the main target of the c-Jun N-terminal kinase (JNK) downstream. The AP-1 binding site at -1043/-1037 was proved to be indispensable for the hST8Sia V gene-specific expression in U87MG cells by site-directed mutagenesis. Moreover, the transcriptional activation of hST8Sia V gene in U87MG cells was strongly inhibited by a specific JNK inhibitor, SP600125. These results suggest that the hST8Sia V gene-specific expression in U87MG cells is controlled by JNK/AP-1 signaling pathway.
Synthesis of dual-modified Fe-doped and carbon-coated Li4Ti5O12 anode based on industrial H2TiO3 for Li-ion batteries
Authors: Jiang Xinyu , Ma Guangqiang , Chen Qiyuan , Ge Hongwei , Yan Beilei , Deng Lin , Tian Congxue , Wu Chuanbao , Zhu Qinmei 
Published: August 2023

Abstract
Spinel Li4Ti5O12 (LTO) is a promising candidate for lithium-ion battery anodes because of its exceptional stability and safety. However, its extensive application is limited by a high comprehensive cost, poor electronic conductivity, and other inherent defects. This work presents a novel synthesis procedure to synthesize carbon-coated Fe-doped LTO composites through carbon reduction, in the presence of Fe-containing industrial H2TiO3 as the titanium source, and glucose as the carbon source. The presence of the Fe-dopant is confirmed through XRD, with Rietveld refinement and EDS experiments. Results show that Fe2+ replaces a portion of Ti4+ after doping, leading to an increase in the LTO cell parameters and the corresponding cell volume. FLTO/C, presents a capacity of 153.79 mAh g-1 at 10 C, and the capacity decay per cycle is only 0.0074% after 1000 cycles at 5 C. Moreover, EIS experiments indicate that the incorporation of Fe and carbon lowers the charge transfer resistance and improves the diffusion and migration of Li+. Notably, since this preparation process requires no additional Fe source as a raw material, it is simple, cost-effective, and suitable for large-scale production and further application.
Enhancing PLA Toughness with Minimal PBAT Additives: Unveiling the Role of Phase Interface and Particle Size through In Situ Reactive Compatibilization
Authors: Li Lin , Li Tian-xiang , Zhao De-fang , Xie Yu-hui , Wu Feng , Xie Delong , Wang Chi , Liu Yuxin , Mei Yi 
Published: August 2023

AbstractPolylactide (PLA) was melt blended with low amounts of poly(butylene adipate-co-terephthalate) (PBAT) using a simple reactive extrusion process herein, aiming to address the inherent brittleness of PLA without significantly compromising its stiffness. PLA/PBAT (90/10) blends with a small amount of peroxide (0.02 phr) and a second crosslinker agent TAIC (triallyl isocyanurate) were produced to explore the structure-performance relationship evolution in reactive extrusion. The results showed that the PLA blend with an appropriate amount of TAIC (i.e., 1.0 phr) exhibited a remarkable increase in elongation at break, reaching as high as 76.8%, which was 22 times higher compared to pure PLA and 6.8 times higher than unmodified PLA/PBAT blends. Furthermore, the sample with high elongation also demonstrated a high stiffness, boasting a Young's modulus of 1.6 GPa and a yield strength of 43 MPa. It was evident that both interfacial adhesion and PBAT size significantly influenced the stretchability of the PLA/PBAT blends. The combination of enhanced compatibility and optimized PBAT phase size of approximately 1.0 µm worked synergistically to enhance the toughness of PLA. Notably, either larger or smaller particle sizes did not contribute favorably to enhancing the toughness of PLA, even if compatibility was improved. The addition of small amounts of TAIC successfully reduced the PBAT phase size but did not enhance compatibility, leading to subpar mechanical performance. Conversely, higher TAIC contents resulted in over-crosslinking, despite considerable improvements in compatibility. This study offers a versatile, scalable, and practical method to prepare fully biodegradable PLA blends with high toughness.
Ab initio protein structure prediction – the necessary presence of external force field as it is delivered by Hsp40 chaperone
Authors: Roterman Irena , Stapor K , Konieczny L 
Published: August 2023

Abstract
Background The aqueous environment directs the protein folding process towards the generation of micelle-type structures, which results in the exposure of hydrophilic residues on the surface (polarity) and the concentration of hydrophobic residues in the center (hydrophobic core). Obtaining a structure without a hydrophobic core requires a different type of external force field than those generated by a water. The examples are membrane proteins, where the distribution of hydrophobicity is opposite to that of water-soluble proteins. Apart from these two extreme examples, the process of protein folding can be directed by chaperones, resulting in a structure devoid of a hydrophobic core.Results The current work presents such example: DnaJ Hsp40 in complex with alkaline phosphatase PhoA-U (PDB ID − 6PSI) - the client molecule. The availability of WT form of the folding protein - alkaline phosphatase (PDB ID − 1EW8) enables a comparative analysis of the structures: at the stage of interaction with the chaperone and the final, folded structure of this biologically active protein. The fuzzy oil drop model in its modified FOD-M version was used in this analysis, taking into account the influence of an external force field, in this case coming from a chaperone.Conclusions The FOD-M model identifies the external force field introduced by chaperon influencing the folding proces. The identified specific external force field can be applied in Ab Initio protein structure prediction as the environmental conditioning the folding proces.
Local delivery of Doxorubicin prodrug via lipid nanocapsule-based hydrogel for the treatment of glioblastoma
Authors: Wang Mingchao , Bergès Raphaël , Malfanti Alessio , Préat Véronique , Bastiancich Chiara 
Published: August 2023

Abstract
Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a novel treatment that combines the advantages of nanomedicine and local drug delivery to target these infiltrating GBM cells. We developed an injectable lipid nanocapsules (LNC)-based formulation loaded with lauroyl-doxorubicin prodrug (DOXC12). Firstly, we demonstrated the efficacy of intratumoral administration of DOXC12 in GL261-GBM-bearing mice, which extended mice survival. Then, we formulated an injectable hydrogel by mixing the appropriate amount of prodrug with the lipophilic components of LNC. We optimized the hydrogel by incorporating cytidine-C16 (Cyt-C16) to achieve a mechanical stiffness adapted for an application in the brain post-surgery (DOXC12-LNCCL). DOXC12-LNCCL exhibited high DOXC12 encapsulation efficiency (95%) and a size of approximately 60 nm with sustained drug release in vitro for over 1 month. DOXC12-LNCCL exhibited enhanced cytotoxicity compared to free DOXC12 (IC50 of 49 and 89 nM, respectively) on GL261 GBM cells and prevented growth of GL261 spheroids cultured on organotypic brain slices. In vivo, post-surgical treatment with DOXC12-LNCCL significantly improved the survival of GL261-bearing mice. The combination of this local treatment with the systemic administration of anti-inflammatory drug ibuprofen further delayed the onset of recurrences. In conclusion, our study presents a promising therapeutic approach for the treatment of GBM. By targeting residual GBM cells and reducing the inflammation post-surgery, we present a new strategy to delay the onset of recurrences in the gap period between surgery and standard of care therapy.