bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative evaluation of therapeutic efficacy and safety of microneedling alone versus microneedling with hyaluronic acid in post-acne scarring
Authors: Bano Rubeena , Brar Balvinder K , Kumar Sumir 
Published: August 2023

Abstract

Background:
Facial acne scars are perceived negatively by society; in an era where everyone wants to look their best, acne and its sequelae are a great source of stress driving down self-worth and elevating the risk of depression and anxiety. It affects over 95% of acne patients, particularly in nodulocystic, conglobate, and fulminans varieties. Various treatment modalities are available, but no single modality is 100% curative. Microneedling produces controlled skin injury, releasing various growth factors and setting up a healing cascade, and laying down collagen as a result. Hyaluronic acid plays an important role in wound healing by creating physiological conditions in the extracellular matrix for the proliferation, migration, and organization of dermal cells.

Aims and Objectives:
To compare the therapeutic efficacy and safety of microneedling alone and microneedling with hyaluronic acid in acne scars.

Materials and Methods:
Sixty patients of age 18–40 years with clinically diagnosed acne scars were recruited and randomly divided into two groups of 30 each. Three sittings were done at an interval of 3 weeks of microneedling alone to Group A and microneedling with hyaluronic acid to Group B and followed up with two visits 4 weeks apart. Scoring was done with Goodman Quantitative Global Scarring Grade System. Side effects, patient satisfaction score, and pre and postprocedure Dermatological Life Quality Index (DLQI) were also recorded.

Results:
The female:male ratio was 3:2, mean age was 26.90 ± 4.90 years in Group A and 24.43 ± 5.39 years in Group B. Overall, 60% patients had a duration of 2–5 years, and unmarried patients outnumbered married ones in both groups. The combination morphology of the scars was the most common finding. In Group A mean Goodman Quantitative Global Scarring Grade System score reduced from baseline 24.13 ± 7.96 to 16.3 ± 7.2, and in Group B, from 27.73 ± 7.86 to 18.20 ± 7.12 at 17 weeks, this decrease was gradual and statistically significant. The patient satisfaction score for Group B (6.20 ± 1.45) was only slightly higher than that of Group A (5.73 ± 1.31). DLQI for Group A decreased from 7.77 to 4.10 and in Group B from 7.63 to 5.00. Both procedures were safe, with over 80% patients experiencing no side effects.

Conclusion:
The majority of patients showed “moderate” improvement in both groups; however, more patients in microneedling with hyaluronic acid group showed “good” and “very good” results at the end of the treatment completion. These are easy, office-based procedures not requiring training or any high-end machine, especially useful in resource-limited setups; the use of hyaluronic acid can enhance the efficacy of microneedling alone.
Efficacy of 15% trichloroacetic acid peel versus 35% glycolic acid peel in acanthosis Nigricans: A randomized open-label study
Authors: Bharati Bharati , Sarkar Rashmi , Garg Taru , Goyal Rajeev , Mendiratta Vibhu 
Published: August 2023

Abstract

Introduction:
Acanthosis Nigricans (AN) is an acquired disorder of keratinization. It presents as hyperpigmentation, velvety texture of skin that can involve any part of the body including the face. Different topical, systemic therapies, or physical therapies including laser have been explored. However, there are not many randomized controlled studies for the majority of therapy alternatives besides lifestyle modifications and weight reduction.

Objectives:
The aim of this study was to compare the effectiveness of 15% trichloroacetic acid (TCA) and 35% glycolic acid (GA) peel for AN.

Materials and Methods:
Forty participants were included and randomized into two groups. In groups A and B, peeling with 15% TCA and 35% GA was done, respectively. The effectiveness of each peel was assessed using changes in the Acanthosis Nigricans Area and Severity Index Score (ANASI) and Physician Assessment Score. Statistical analysis included Wilcoxon–Mann–Whitney test, Friedman test, and generalized estimating equations.

Results:
The overall change in ANASI over time was compared in the two groups using the generalized estimating equations method. A significant difference was observed in the trend of ANASI over time between the two groups (P < 0.001). TCA peel group showed more change in ANASI as compared with GA peel group.

Conclusion:
In our research, 15% TCA has a better efficacy when compared with 35% GA peel after three sessions of chemical peeling. We therefore recommend the use of 15% TCA peel in AN as a safe and effective treatment option. However, more comprehensive randomized control studies are required for supporting data.
DİYABETİK KETOASİDOZ TANISIYLA PEDİATRİ YOĞUN BAKIM ÜNİTESİNE YATAN ÇOCUKLARIN İLK BULGULARI, AĞRI VE GÜNLÜK YAŞAM AKTİVİTELERİNİN DEĞERLENDİRİLMESİ
Authors: BARAN Gülbeyaz , TURAN Engin , TURAN Mensure 
Published: August 2023

Amaç: Bu araştırma diyabetik ketoasidoz tanısıyla çocuk yoğun bakım ünitesine yatan çocukların ilk bulguları, ağrı ve günlük yaşam aktivitelerinin değerlendirilmesini belirlemek amacıyla yapıldı.
Yöntem: Araştırma, Eğitim ve Araştırma Hastanesine bağlı Çocuk Hastalıkları Hastanesinin Çocuk Yoğun Bakım Kliniğinde Ekim-Aralık 2021 tarihleri arasında yürütüldü.
Araştırma kesitsel, ilişki arayıcı tanımlayıcı tiptedir. Bu araştırmanın örneklemini, diyabetik ketoasidoz tablosuyla yatışı yapılan 54 çocuk oluşturmaktadır. Verilerin toplanmasında Wong Baker Ağrı Değerlendirme Ölçeği, Glaskov Koma Skalası ve Katz Günlük Yaşam Aktiviteleri (GYA) indeksi kullanıldı. Araştırma verilerinin analizinde; çocukların ve ebevynlerin tanımlayıcı özelliklerin belirlenmesinde yüzdelik, çocukların hastaneye geldikleri anda alınan ilk değerlendirme bulgularının değerlendirilmesinde ortalama, ölçekler arası ilişki durumunu belirlemede ise korelasyon analizi testi kullanılmıştır.
Bulgular: GYA indeksi ile VAS arasında negatif yönde orta düzeyde (r=-.321) ilişki olduğu, GYA indeksi ile GKS arasında pozitif yönde iyi düzeyde (r=.540) ilişki olduğu, VAS ile GKS arasında negatif yönde orta düzeyde (r=-.416) ilişki olduğu görülmektedir.
Sonuçlar ve Öneriler: Çocukların günlük yaşam aktiviteleri kötüleşirken, çocukların ağrıları artmaktadır. Günlük yaşam aktivitelerinin iyileşmesi sonucunda çocukların hayat kalitesinin arttmasına bağlı olarak bilinç durumunda da iyileşme olduğu bulunmuştur.
Use of lentil flour in special purpose bread
Authors: Yevchuk Ya. V. , Novikova T. P. , Vyshynskyi A. V. , Shevchuk O. Yu. 
Published: August 2023

Purpose. To study the peculiarities of the indicators of quality formation of bread made with the addition of lentil flour.
Methods. The research was carried out according to the technology of bakery and pasta production. Products made from wheat flour of the first grade and rye were used as a control, while the bread made with the addition of 5 to 30% of lentil flour (variety 'Chrysolit'. The bread was baked in a cabinet oven at a temperature of 220 ± 2°C. Both ready dough and end product was evaluated by physico-chemical and organoleptic indicators.
Results. The addition of lentil flour had different effects on the quality of wheat and rye bread. In particular, in wheat flour dough, with the addition of 5–30% lentil flour, the final acidity increased from 2.5 to 2.7–3.8 degrees, or 1.1–1.5 times. The release of carbon dioxide decreased from 848 to 646–790 cm3/100 g, or 1.1–1.3 times. The water content of the dough changed insignificantly. The duration of maturation decreased from 63 to 41–57 min, porosity from 78 to 52–74%. Baking increased from 4.3 to 4.7–8.5%, drying – from 4.5 to 5.0–7.0%. In the rye flour dough, the acidity decreased from 2.8 degrees in the control to 1.5–2.3 degrees, or 1.2–1.9 times with the addition of 5–30% lentil flour. The water content of the dough was at the control level, as it did not change significantly. With the addition of 5–10% lentil flour, the duration of fermentation decreased from 60 to 50–55 min, and with the addition of 15–30% lentil flour, it increased to 62–67 min. With the addition of 5–30% lentil flour, dimensional stability decreased from 0.50 to 0.25–0.48, porosity – from 72 to 42–67%. Baking of rye bread increased from 5.5% in the control to 5.8–9.4%, and drying increased from 6.0 to 6.6–8.8%, depending on the variant of the experiment. It should be noted that the addition of 5–15% lentil flour did not change the appearance of wheat and rye bread. The addition of 20–30% lentil flour ensured the formation of bread that did not meet the standards of DSTU 7517:2014. Wheat Flour Bread. General Technical Conditions and DSTU 4583:2006. Rye Bread and a Mixture of Rye and Wheat flour. General technical conditions.
Conclusions. Adding 5–15% lentil flour to a wheat or rye bread recipe does not change the appearance of the bread. The surface of the bread was smooth without cracks and dents, the color of the crust was light green, and the color of the crumb was light, with barely noticeable specks of lentil flour. At the same time, the acidity increases and the release of carbon dioxide from the dough decreases. In addition, the addition of 5–15% lentil flour increases the baking and drying of wheat and rye bread, and the duration of maturation, dimensional stability, specific volume and porosity decrease. Adding 20–30% of lentil flour to the bread recipe is impractical, as it greatly spoils its appearance.
Retrasos del Avance de Ejecución de Obras y sus posibles causas en el Gobierno Regional de Pasco - 2022
Authors: Valqui Castañeda Carlos Alfredo , Yglesias Jauregui Miguel Angel 
Published: August 2023

El presente artículo titulado "Retrasos del Avance de Ejecución de Obras y sus posibles causas en el Gobierno Regional de Pasco - 2022" examina las posibles causas que puedan originar retrasos en la ejecución de las obras en la región de Pasco. El estudio identifica varias razones para los retrasos, entre ellas fallas en el expediente técnico, factores climáticos, adicionales de obra, cálculo de reajustes, mayores metrados, y factores importantes generados por la pandemia COVID-19.
El estudio resalta la importancia de los cambios en el alcance de los proyectos y los trabajos adicionales, los cuales pueden retrasar significativamente la ejecución de los proyectos. Además, los factores climáticos también pueden retrasar los proyectos de construcción en la región.
El artículo destaca que la pandemia COVID-19 también ha tenido un impacto significativo en la ejecución de proyectos de construcción. Los trabajos tuvieron que ser suspendidos temporalmente, lo que afectó el avance del proyecto y retrasó la entrega de las obras.
Otras posibles causas de retrasos incluyen fallas en la coordinación entre los diferentes equipos y contratistas, retrasos en la aprobación de permisos y licencias, así como retrasos en el cálculo de los reajustes de precios.
El estudio concluye que la identificación temprana y la resolución oportuna de estos problemas pueden ayudar a minimizar los retrasos y garantizar la finalización exitosa de los proyectos de construcción. Además, se sugiere la implementación de medidas de gestión de riesgos y la planificación adecuada para asegurar que se tomen medidas preventivas para evitar o minimizar los retrasos.
La presente investigación, cuyo enfoque es cualitativo se justificó mediante la metodología PRISMA, con el fin de obtener información de trabajos desarrollados referente a la problemática señalada, para el presente estudio se utilizaros bases de datos como: SCIELO, GOOGLE ACADÉMICO, REDALYC Y DIALNET, con un criterio de temporalidad basada en información de los últimos 4 años (2019 – 2022).
USO DE BETABLOQUEADORES NO TRATAMENTO DE HEMANGIOMA INFANTIL
Authors: Souza Abdala Rosangela Cristina , Teixeira do Amaral Alexandre , Balista Canevarolo Pedro Augusto , Dantas Caldeira Aeissami Mirelly , Vasconcelos Carvalho Natália , Fonseca de Oliveira Ana Flávia , Ferreira da Silva Thiarles , Silva Borges de Oliveira Filipe , Gonçalves Cherain Luiz Gabriel , Ramires de Souza Liberato Wesley 
Published: August 2023

Os hemangiomas infantis (HIs) são tumores vasculares benignos comuns em crianças. As opções de tratamento históricas e atuais incluem terapia médica, ressecção cirúrgica, terapia a laser ou injeções intralesionais diretas de esteroides. Objetivo: agrupar os principais betabloqueadores utilizados no tratamento de hemangioma infantil e abordar sua eficácia e segurança. Metodologia: Com base em todos os passos adotados, a pergunta norteadora definida foi: “O uso de betabloqueadores em pacientes com hemangioma infantil, quando comparado ao uso de placebo ou outras drogas, é eficaz na resolução ou diminuição das lesões?”. Inicialmente, foram encontrados 220 estudos. Após a aplicação dos critérios de busca, foram escolhidos sete artigos para compor a revisão de literatura. Resultados e discussão: observa-se que os betabloqueadores são amplamente utilizados no tratamento de HIs, sendo principalmente eficazes nas fases proliferativa precoce e inicial. O betabloqueador mais utilizado é o propranolol, porém, em casos de sensibilidade ou eventos adversos graves, podem ser utilizados timolol, atenolol, carteolol e betaxolol, tanto em apresentação tópica quanto oral. A terapia conjunta com dois betabloqueadores também se mostrou efetiva na resolução de His. Conclusão: o uso de betabloqueadores no tratamento de hemangioma infantil é benéfico aos pacientes, sendo seguro e efetivo, além de apresentar pouco ou nenhum efeito colateral sistêmico.
Impact of Seating and Mobility Services for Individuals With Disabilities in El Salvador
Authors: Short Nathan , Peters Heather St. , Eckert Jonah , Grady Natalie , Kline Erin , Weber Holly 
Published: August 2023

Abstract
Importance: Outcomes research on the impact of seating and mobility services delivered using a short-term medical mission (STMM) model is limited.
Objective: To evaluate the impact of seating and mobility services on the occupational performance of individuals with disabilities in El Salvador.
Design: One-group retrospective pretest–posttest.
Setting: Clinical (El Salvador).
Participants: Individuals with disabilities in El Salvador.
Outcomes and Measures: Survey and the standardized Wheelchair Outcome Measure (WhOM) for those who received a wheelchair as their mobility device.
Method: Participants rated satisfaction with performance of preferred in-home and out-of-home occupations on the WhOM before and after receiving seating and mobility services.
Results: For most survey questions assessing the impact on activities of daily living, more than 86% of the respondents selected agree or strongly agree. Nearly half of the respondents reported that questions regarding work and education were not applicable. Participants’ WhOM scores (n = 86) demonstrated a statistically significant improvement in performance satisfaction for both in-home (p &lt; .001; d &gt; 1) and out-of-home (p &lt; .001; d &gt; 1) occupations after they received services, with a huge effect size (d &gt; 2).
Conclusions and Relevance: The findings suggest that seating and mobility services provided by rehabilitation professionals in El Salvador improved occupational performance for people with disabilities. Compared with STMMs that solely provide equipment, the findings emphasize the importance of professional service provision with education and training as best practice.
What This Article Adds: Seating and mobility services delivered through a STMM model may improve occupational performance for individuals with disabilities. However, STMMs should be carefully planned in collaboration with in-country partners, provide customized seating systems, and include education and training from licensed rehabilitation professionals.
Interventions That Foster Self-Determination in Autistic Individuals (2013–2021)
Authors: Patten Kristie , Murthi Kavitha , Chen Yu-Lun , Onwumere Dora , Shore Stephen 
Published: August 2023

Abstract
Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s (AOTA’s) Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. This Systematic Review Brief presents findings from a systematic review that examined interventions to support and improve self-determination for autistic1 individuals.
The Reagan Revolution and the Rise of the New Right
Authors: Heineman Kenneth 
Published: August 2023

This book covers Ronald Reagan’s long rise to the presidency and the conservative political revolution he brought about in the 1980s. Spurning the moderate values and policies Republicans had previously championed, Reagan’s revolution continues to play an outsized role in America’s political life. This important reference book gives browsers and readers alike an opportunity to focus on many of the intertwined issues of the 1980s: abortion, gay rights, law and order, the Cold War, tax cuts, de-industrialization, the Religious Right, and the political divisions that made Reagan’s legislative victories possible.
The book opens with a concise biography covering Reagan’s rise from radio personality and actor to governor and president. Subsequent chapters cover politics and policy. Chapters also include an important review of Reagan’s legendary public relations operations (“morning in America” and the perfection of the television photo op) and the ways in which 1980s popular culture influenced and was influenced by his presidency. This section portrays Reagan as a product of Hollywood who keenly understood the importance of public opinion and creating a positive image.
Sexual Assault and Harassment in America
Authors: Koon-Magnin Sarah 
Published: August 2023

This wide-ranging resource uses evidence-based documentation to examine claims and beliefs—and provide the facts—about sexual assault and harassment and other forms of sexual violence in the United States.
Each title in the Contemporary Debates series examines the veracity of controversial claims or beliefs surrounding a major political/cultural issue in the United States. They do so to give readers a clear and unbiased understanding of current issues by informing them about falsehoods, half-truths, and misconceptions—and confirming the factual validity of other assertions—that have gained traction in America’s political and cultural discourse. Ultimately, this series has been crafted to give readers the tools for a fuller understanding of issues, events, policies, and laws that occupy center stage in American life and politics.
This volume in the series addresses the issue of sexual violence in the U.S. It includes chapters devoted to quantifying the extent of the problems of sexual assault and harassment; demographic groups most likely to experience sexual violence; physical, emotional, and societal impacts of sexual assault; how investigations of sex-related charges are conducted; laws and policies pertaining to both victims and offenders; and sexual violence prevention and response services outside of the criminal justice system."
Shakespeare's World: The Comedies
Authors: Pendergast John 
Published: August 2023

With summaries, discussions, and excerpts from primary source documents, this book examines Shakespeare's world through careful consideration of the historical background of four of his comedies.
Comedy was popular during the Renaissance, and it was also one of Shakespeare�s specialties. The four plays discussed in this book, A Midsummer Night�s Dream, The Merchant of Venice, Twelfth Night and The Tempest, span Shakespeare�s career and remind us that Shakespeare, more than any of his contemporaries, explored the possibilities of comedy, consistently developing new approaches to the genre.
Shakespeare was a fairly traditional playwright, well aware of the long tradition of comedy, which dates back to the Greeks and Romans. This book places Shakespeare�s comedies in their historical context. It includes dedicated chapters on each of the four comedies, with each chapter providing a plot summary, a discussion of the play�s historical background and significance, and excerpts from primary source documents related to the play. An introduction surveys the historical background of the plays, while a timeline chronicles key events that influenced them. Suggestions for further reading direct readers to additional sources of information.
The Story of the Chippewa Indians
Authors: Gagnon Gregory O. 
Published: August 2023

This single-volume book provides a narrative history of the Chippewa tribe with attention to tribal origins, achievements, and interactions within the United States.
Unlike previous works that focus on the relationships of the Chippewa with the colonial governments of France, Great Britain, and the United States, this volume offers a historical account of the Chippewa with the tribe at its center. The volume covers Chippewa history chronologically from about 10,000 BC to the present and is geographically comprehensive, detailing Chippewa history as it occurred in both Canada and the United States, from the Great Lakes to Montana to adjacent Canadian provinces.
Written by a Chippewa scholar, the book synthesizes key scholarly contributions to Chippewa studies through the author's own interpretive framework and tells the history of the Chippewa as a story that encompasses the culture's traditions and continued tenacity. It is organized into chronological chapters that include sidebars and highlight notable figures for ease of reference, and a timeline and bibliography allow readers to identify causal relationships among key events and provide suggestions for further research.
Taxation
Authors: Dieterle David A. 
Published: August 2023

This engaging and accessible book is a must-read for every taxpayer, young and old. It explores the many forms of taxation; how taxes are created, collected, and spent; and why certain aspects of taxation are so controversial.
“In this world, nothing can be said to be certain, except death and taxes.” Benjamin Franklin wrote this now-famous quote more than 200 years ago, and taxation remains just as important (and inevitable) today as then. Taxes are a fact of life for almost everyone, and the public goods and services they pay for are enjoyed by all citizens.
While taxes are undeniably necessary, the specifics of what should be taxed, who should pay taxes, and at what rate remain hotly debated by economists, government officials, and regular citizens. The first in Greenwood’s new Student Guides to Business and Economics series, Taxation gives readers an in-depth yet reader-friendly look at one of economics’ foundational concepts. Using simple language and relevant real-world examples, the book explores the different forms of taxation, the necessary components of any tax, how taxes are created and collected, and much more. It also highlights contemporary controversies related to taxation, including whether or not “sin taxes” actually discourage unwanted behaviors like smoking and how best to simplify the tax filing process.