bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sex difference in the associations among risk factors with depression in a large Taiwanese population study
Authors: Tseng Hsin , Lee Jia-In , Geng Jiun-Hung , Chen Szu-Chia 
Published: March 2023

BackgroundDepression is a common psychiatric health issue affecting an estimated 5% of adults worldwide, and it can lead to disability and increased economic burden. Consequently, identifying the factors associated with depression as early as possible is a vital issue. The aim of this study was to explore these associations in a large cohort of 121,601 Taiwanese participants in the Taiwan Biobank, and also to identify sex differences in the associations.MethodsThe study cohort included 77,902 women and 43,699 men (mean age, 49.9 ± 11.0 years), who were further classified into those with depression (n = 4,362; 3.6%) and those without depression (n = 117,239; 96.4%).ResultsThe results of multivariable analysis showed that female sex (vs. male sex; odds ratio = 2.578; 95% confidence interval = 2.319–2.866; p &lt; 0.001) was significantly associated with depression. Older age, diabetes mellitus (DM), hypertension, low systolic blood pressure (SBP), smoking history, living alone, low glycated hemoglobin (HbA1c), high triglycerides, and low uric acid were significantly associated with depression in the men. In the women, older age, DM, hypertension, low SBP, smoking history, alcohol history, education level of middle and high school (vs. lower than elementary school), living alone, high body mass index (BMI), menopause, low HbA1c, high triglycerides, high total cholesterol, low estimated glomerular filtration rate (eGFR), and low uric acid were significantly associated with depression. Further, there were significant interactions between sex and DM (p = 0.047), smoking history (p &lt; 0.001), alcohol use (p &lt; 0.001), BMI (p = 0.022), triglyceride (p = 0.033), eGFR (p = 0.001), and uric acid (p = 0.004) on depression.ConclusionIn conclusion, our results showed sex differences in depression, and the women were significantly associated with depression compared to men. Furthermore, we also found sex differences among the risk factors associated with depression.
Occupational low back pain prevention capacity of nurses in China: A multicenter cross-sectional study
Authors: Liu Qianru , Liu Xue , Lin Huijing , Sun Yu , Geng Li , Lyu Yongli , Wang Mengna 
Published: March 2023

IntroductionNurses have a high prevalence of occupational low back pain, especially since the outbreak of the COVID-19 pandemic, which has increased the nurses' workloads. It has brought a huge burden on nurses and their professional development. Nurses' occupational low back pain prevention capacity is the logical starting point and core of interventions to prevent its occurrence. To date, there is no study investigating it with a scientific scale. Therefore, a multicenter cross-sectional study was conducted to explore the current status of nurses' capacity in occupational low back pain prevention and its influencing factors in China.MethodsUsing a two-stage, purposive and convenience mixed sampling method, 1331 nurses from 8 hospitals across 5 provinces (Hubei, Zhejiang, Shandong, Henan, and Sichuan) in the southern, western, northern, and central areas of mainland China were involved in this study. The demographic questionnaire and occupational low back pain prevention behavior questionnaire were used for data collection. The descriptive analysis, univariate analysis, and multiple stepwise linear regression were used for data analysis.ResultsThe results showed that the occupational low back pain prevention behavior questionnaire score was 89.00 (80.00, 103.00) [M (Q1, Q3)], which indicated that nurses' ability was at a moderate level. Participation in prevention training before, perceived stress at work, and working hours per week were predictors for nurses' occupational low back pain prevention capacity.DiscussionTo improve nurses' prevention ability, nursing managers should organize various training programs, strengthen regulations to reduce nurses' workload and stress, provide a healthy workplace, and offer incentives to motivate nurses.
ATHLOS Healthy Aging Scale score as the predictor of all-cause mortality in Poland and Czechia
Authors: Kozela Magdalena , Pająk Andrzej , Szafraniec Krystyna , Ayuso-Mateos José Luis , Bobak Martin , Lu Wentian , Pikhart Hynek , Polak Maciej , Sanchez-Niubo Albert , Stepaniak Urszula , Haro Josep Maria 
Published: March 2023

BackgroundThe ATHLOS consortium (Aging Trajectories of Health–Longitudinal Opportunities and Synergies) used data from several aging cohorts to develop a novel scale measuring healthy aging comprehensively and globally (ATHLOS Healthy Aging Scale). In the present study, we assessed the predictive performance of the ATHLOS Healthy Aging Scale for all-cause mortality in middle-aged and older adults.MethodsData from the Polish and Czech HAPIEE (Health Alcohol and Psychosocial factors In Eastern Europe) prospective cohorts were used. There were 10,728 Poles and 8,857 Czechs recruited. The ATHLOS Healthy Aging Scale score was calculated for all participants using data from the baseline examination carried out from 2002 to 2005. The follow-up for all-cause mortality was completed over 14 years. The associations between quintiles of the ATHLOS Healthy Aging Scale and all-cause mortality were estimated using Cox proportional hazards models.ResultsA total of 9,922 Polish and 8,518 Czech participants contributed ATHLOS Healthy Aging Scale and mortality data with 1,828 and 1,700 deaths, respectively. After controlling for age, the ATHLOS Healthy Aging Scale score was strongly associated with mortality in a graded fashion for both genders and countries (hazard ratios for lowest vs. highest quintile were 2.98 and 1.96 for Czech and Polish women and 2.83 and 2.66 for Czech and Polish men, respectively). The associations were only modestly attenuated by controlling for education, economic activity, and smoking, and there was further modest attenuation after additional adjustment for self-rated health.ConclusionThe novel ATHLOS Healthy Aging Scale is a good predictor of all-cause mortality in Central European urban populations, suggesting that this comprehensive measure is a useful tool for the assessment of the future health trajectories of older persons.
Untreated substance use disorder affects glycemic control: Results in patients with type 2 diabetes served within a network of community-based healthcare centers in Florida
Authors: Horigian Viviana E. , Schmidt Renae D. , Duan Rui , Parras Daniel , Chung-Bridges Katherine , Batycki Jacob N. , Espinoza Kevin , Taghioff Peyman , Gonzalez Sophia , Davis Carly , Feaster Daniel J. 
Published: March 2023

IntroductionPatients with diabetes and comorbid substance use disorders (SUD) experience poor diabetes management, increased medical complications and mortality. However, research has documented that patients engaged in substance abuse treatment have better management of their comorbid conditions. The current study examines diabetes management among patients with type 2 diabetes, with and without comorbid SUD, receiving care at Florida-based Federally Qualified Health Centers (FQHC) of Health Choice Network (HCN).MethodsA retrospective analysis was conducted using deidentified electronic health records of 37,452 patients with type 2 diabetes who received care at a HCN site in Florida between 2016 and 2019. A longitudinal logistic regression analysis examined the impact of SUD diagnosis on achievement of diabetes management [HbA1c &lt; 7.0% (53 mmol/mol)] over time. A secondary analysis evaluated, within those with an SUD diagnosis, the likelihood of HbA1c control between those with and without SUD treatment.ResultsThe longitudinal assessment of the relationship between SUD status and HbA1c control revealed that those with SUD (N = 6,878, 18.4%) were less likely to control HbA1c over time (OR = 0.56; 95% CI = 0.49–0.63). Among those with SUD, patients engaged in SUD treatment were more likely to control HbA1c (OR = 5.91; 95% CI = 5.05–6.91).DiscussionFindings highlight that untreated SUD could adversely affect diabetes control and sheds light on the opportunity to enhance care delivery for patients with diabetes and co-occurring SUD.
Numerical modeling of solar wind and coronal mass ejection in the inner heliosphere: A review
Authors: Zhang Man , Feng Xueshang , Li Huichao , Xiong Ming , Shen Fang , Yang Liping , Zhao Xinhua , Zhou Yufen , Liu Xiaojing 
Published: March 2023

The predictions of plasma parameters in the interplanetary medium are the core of space weather forecasts, and the magnetohydrodynamics (MHD) numerical simulation is an important tool in the prediction of plasma parameters. Operational space weather forecasts are commonly produced by a heliosphere model whose inner boundary is set at 18 Rs or beyond. Such predictions typically use empirical/physics-based inner boundary conditions to solve the MHD equations for numerical simulation. In recent years, significant progress has been made in the numerical modeling of the inner heliosphere. In this paper, the numerical modeling of solar wind and coronal mass ejection in the inner heliosphere is reviewed. In particular, different inner boundary conditions used in the simulation are investigated since the MHD solutions are predetermined by the treatment of the inner boundary conditions to a large extent. Discussion is made on further development of the heliosphere model.
A cross-sectional study of Canadian children's valuation of literacies across social contexts
Authors: Bremer Emily , Jefferies Philip , Cairney John , Kriellaars Dean 
Published: March 2023

BackgroundChildren, on average, do not engage in sufficient physical activity to reap the physical, mental, and social health benefits. Understanding the value that children place on movement across social contexts, and the relative ranking of this valuation, may help us to understand and intervene on activity levels.MethodThis exploratory study examined the valuation of reading/writing, math, and movement across three social contexts (school, home, with friends) among children 6–13 years of age (N = 7,845; 51.3% male). Subjective task values across contexts were assessed with the valuing literacies subscale of the PLAYself. One-way Kruskal-Wallis ANOVAs were performed to test for differences between contexts and between literacies, respectively.ResultsSex differences and age-related variation were explored. Valuations of reading/writing (d = 1.16) and math (d = 1.33) decreased across context (school &gt; family &gt; friend), while the valuation of movement was relatively stable (d = 0.26). Valuations differed substantially with friends (p &lt; 0.001, d = 1.03). Sex dependent effect sizes were minimal (d = 0.05–0.11).ConclusionsMovement is highly valued by children across social contexts; thus, programming across contexts should be prioritized to align with their valuation.
Three types of end-to-side microvascular anastomosis training models using rat common iliac arteries
Authors: Xiao Zongyu , Wang Ji , Guo Jingpeng , Pan Qi 
Published: March 2023

Background: Instead of only practicing these perfectly matched end-to-side anastomoses in microsurgical laboratories, we must learn how to perform these so-called “imperfect” end-to-side anastomoses in the laboratory.MethodsThree types of end-to-side microvascular anastomoses using the rat common iliac artery (CIA), one with the proximal end of the CIA to the contralateral side of the CIA, another with the distal end of the CIA to the contralateral side of the CIA, and the third with the distal end of the CIA to the ipsilateral side of the common iliac vein (CIV), were presented to simulate different end-to-side anastomosis situations in a microsurgical laboratory. Diameters of CIA and CIV, distances between temporary clips, the length of arteriotomy or venotomy, and the distribution of stitches were recorded. The patency rates were evaluated immediately after the anastomosis was completed and 30 min later. After animal euthanasia, the donor vessel was cut close to the anastomotic site, and the orifice size and intimal attachment were evaluated by inspecting them through inside the vessel.ResultsThe diameters of the CIA and CIV were 0.8–1.2 mm and 1.2–1.5 mm, respectively. The end-to-side microvascular anastomosis arteriotomy or venotomy is approximately 2.00–2.50 mm, the distance between the aneurysm clips on the recipient CIA or CIV is approximately 4.00–7.00 mm, and the distance between the corner of the arteriotomy or venotomy and the temporary aneurysm clip was 1.00–3.00 mm. Three types of end-to-side anastomoses using the CIA were successfully performed, and 100% patency rates were achieved immediately and 30 min postoperatively. Good distribution of stitches, wide orifice, and intimal attachment were recorded in the study in all groups.ConclusionsThree types of end-to-side anastomoses using rat CIAs could be efficiently used to mimic three different anastomotic situations.
Automatic detection of microcalcifications in whole slide image - comparison of deep learning and standard computer vision approaches
Authors: Clavel Marceau , Sockeel Stéphane , Sockeel Marie , Miquel Catherine , Adam Julien , Lanteri Elisabeth , Pozin Nicolas 
Published: March 2023

<p>Early detection of breast cancer through mammography is crucial for successful treatment. Microcalcifications are small deposits of calcium in breast ducts, they can be an indication of breast cancer and are first detected by mammography. However, their presence must be confirmed by an histopathologist through slides examination. As a help to practitioners, we present an automatic microcalcification detection pipeline in Whole Slide Images (WSI). This pipeline is a patch-based approach, in which patches from epithelial regions are analyzed by a classifier to determine if they contain microcalcifications. We have developed two classifiers for this pipeline, one based on image processing techniques and the other on deep learning. In addition to standard classification metrics, we compare the performance of these two classifiers using custom metrics specifically designed to capture the value brought by the pipeline to pathologists. Both approaches provide promising results. The deep learning classifier has better metrics, but requires more labeled data to be implemented. </p>
Linearized-Trajectory Model-Predictive Controller for Improving Microgrid Short-Term Stability with Real-Time Implementation
Authors: Hamilton Dakota , Navarro Loraine , Aliprantis Dionyios , Pekarek Steven , Zweigle Greg 
Published: March 2023

<p> A model-predictive controller (MPC) for synchronous generator-based microgrids is introduced to enhance voltage, frequency, and transient stability in fast timescales. The centralized controller uses mathematical models of power system dynamics to predict the evolution of system states over a finite horizon based on information from local state observers and relays. The MPC dynamically adjusts the setpoints of existing primary controls to maximize system stability. To address the computational challenges of a real-time MPC implementation due to nonlinear power system dynamics and short sampling intervals, a trajectory linearization technique is applied to the MPC formulation. The proposed controller is validated via a hardware-in-the-loop (HIL) testbed. The testbed includes an implementation of the controller in hardware, which interfaces with a high-fidelity microgrid simulation model running in a realtime simulator. State observers based on the Extended Kalman Filter (EKF), which provide the controller with estimates of the system state, are also implemented. The HIL testbed is used to verify the real-time operation of the controller and evaluate its performance under modeling uncertainties.</p>
Cerebral Toxoplasmosis in an Immunocompetent Patient With Confirmed Covid-19 Positive
Authors: Fradisha Monica , Nareswari Dewi 
Published: March 2023

A case of a 30 years-old male patient, diagnosed with cerebral toxoplasmosis, confirmed HIV, with positive COVID-19. Once he came to the emergency department with a chief complaint of left upper and lower limbs weakness progressing for two days. The patient appeared malnourished and was afebrile and assessed to be well hydrated. He was alert but drowsy and had speech difficulty. A focused neurologic examination was performed and revealed a loss of nasolabial fold indicating facial nerve palsy. Neck stiffness was present and there was reduced motoric power in the left upper and lower limb of 2/5, with positive Babinski sign and Chaddock sign. According to brain CT, showed vasogenic cerebral edema and midline shift. Further laboratory exams showed positive IgG antibodies for Toxoplasma, with a titer exceeding 300 IU/ml, positive serum HIV, with CD4 cell count below 200cell/mm3. Complete blood count study highlighted low haemoglobin and elevated white cell count. He tested positive for COVID-19 by nasopharyngeal swab RT-PCR. Chest CT were done and revealed features of viral pneumonia with ground glass opacity appearance. In summary, we present a patient with cerebral involvement of toxoplasmosis possibly facilitated by pre-existing immunodeficiency as an opportunistic infections of HIV, and with COVID-19 complicated as acute infections. This case report reinforces a potential role for other comorbidities, rather than HIV infection as regards SARS-CoV-2 infection outcomes. For better assessment we need to do MRI.
The contribution of preoperative MRI evaluation to emergency surgical management of perianal abscesses
Authors: Gurbuz Defne , Hot Semih , Egin Seracettin , Kosar Tunc Melis 
Published: March 2023

Objective: Perianal abscesses occur as a result of an infection in the anal gland due to the obstruction of the anal gland ducts opening to the anal crypts. Preoperative use of MRI reduces the risk of recurrence, fistula formation, and postoperative fecal incontinence as it allows detailed anatomical imaging. The aim of this study is to investigate the contribution of preoperative MRI to reducing recurrence and surgical complications in patients who underwent emergency surgery for perianal abscess.
Material and Methods: A total of 206 patients with perianal abscess evaluated and not evaluated with MRI between January 2016 and 2021 were included in this retrospective study. The patients had no history of surgery or local drainage applied to the perianal region. In addition to demographic data of patients, postoperative complications, hospitalization duration, recurrence ratio, and MRI findings are evaluated.
Results: In the preoperative period, recurrence was found in 16 (%13.2) of 121 cases evaluated with MRI, while the disease recurred in 24 (%28.2) of 85 cases who were operated without MRI evaluation. The presence of a fistula was significantly higher while the presence of recurrence was significantly lower in the group that underwent MRI in the preoperative period (p=0.033, p=0.012 respectively).
Conclusion: Contrary to popular belief, surgical treatment of abscesses is not that easy due to the high risk of recurrence, the high rate of association with perianal fistula, and the different types and spreads of abscesses. Therefore, preoperative MRI is the most useful diagnostic method for detecting perianal abscesses and additional pathologies.
Peningkatan keaktifan dan hasil belajar biologi pada kompetensi dasar struktur jaringan penyusun organ pada sistem gerak manusia melalui metode pembelajaran picture and picture bagi siswa kelas XI MIPA 1 pada semester gasal tahun pelajaran 2019 / 2020 SMA
Authors: Nurhayati Titik 
Published: March 2023

Penelitian Tindakan Kelas (PTK) bertujuan untuk meningkatkan keaktifan dan hasil belajar siswa bagi kelas XI MIPA 1 semester gasal tahun pelajaran 2019/2020 SMA Negeri 1 Tunjungan Kabupaten Blora. Penelitian dilaksanakan dalam dua siklus, di mana masing-masing-masing siklus terdiri dari tahap perencanaan, pelaksanaan, pengamatan, dan refleksi. Siklus I terdiri dari tiga pertemuan (tiga kali tatap muka), siklus II terdiri dari 2 pertemuan (duakali tatap muka). Data keaktifan diperoleh dari observasi oleh guru pengajar dan teman sejawat, sedangkan hasil belajar diperoleh dari tes hasil ulangan harian tiap-tiap siklus.Hasil penelitian menunjukkan bahwa hasil observasi keaktifan sudah menunjukkan peningkatan menjadi kategori tinggi. Hal ini dapat dilihat dari rata-rata persentase capaian keaktifan dari siklus II sebesar 87,33% (kategori tinggi). Keaktifan peserta didik dari siklus 1 menuju ke siklus 2 mengalami peningkatan. Yaitu aspek kehadiran naik dari 92,59 % menjadi 100% (kategori tinggi). Aspek keaktifan bertanya dan memberi pendapat naik dari 51,62% menjadi 78,57 (kategori tinggi). Aspek berfikir bersama dalam kelompok naik dari 60,87% menjadi 86,73% (kategori tinggi). Aspek kejujuran dalam mengerjakan tugas naik dari 69,9% menjadi 93,33% (kategori tinggi). Aspek kemampuan dalam berkomunikasi naik dari 57,40% menjadi 79,53% (kategori tinggi) pada perlakuan siklus 2. Hasil belajar peserta didik didapatkan bahwa hasil belajar peserta didik pada siklus 2 mengalami kenaikan 13,37% dibandingkan dengan hasil belajar pada kondisi siklus 1. Persentase peserta didik yang belum memenuhi KKM mengalami penurunan 2,86%. Hal ini ditunjukkan persentase siklus 1 sebesar 14,28% turun menjadi 11,42% pada perlakuan siklus 2. Persentase yang sudah memenuhi KKM mengalami kenaikan 2,86% dari siklus 1 sebesar 85,71% naik menjadi 88,57% pada perlakuan siklus 2. Kesimpulannya bahwa Keaktifan dan Hasil belajar biologi kompetensi dasar struktur jaringan penyusun organ pada sistem gerak manusia bagi kelas XI MIPA 1 semester gasal tahun pelajaran 2019/2020 SMA Negeri 1 Tunjungan Kabupaten Blora meningkat setelah dilaksanakan pembelajaran melalui metode pembelajaran cooperative learning metode Picture and Picture.
Use of e-cigarettes and associated factors among adolescent smokers in Indonesia: Analysis of the Global Youth Tobacco Survey (GYTS) Indonesia 2019
Authors: Marice Marice , Kaseger Henny , Hariyanti Yunida , Hafid Wahyuni , Purnamasari Niluh Desy , Supetran I Wayan , Akbar Hairil , Maretalinia Maretalinia 
Published: March 2023

Background: Electronic cigarette (e-cigarette) is an alternative to reduce the harmfulness of conventional cigarettes. However, there are still pros and cons to using the e-cigarette, especially among adolescents. Instead of reducing the health problem, using e-cigarette even make the illness the same as conventional ones.
Objective: This study aimed to examine the determinant of using e-cigarettes among adolescents and smokers of school age.
Method: This study used the cross-sectional data from the Global Youth Tobacco Survey (GYTS) Indonesia 2019. The national school was selected by proportional random sampling. Around 832 adolescent smokers were eligible for this study.
Results: Among 832 adolescent smokers in this study, about 49.64% of them ever used e-cigarettes. The factors significantly associated with the use of e-cigarettes were money pocket and the use of other forms of smoked tobacco. However, other independent variables, such as age, gender, teachers smoking during school hours, and parent smoking, were not significantly associated with using e-cigarettes.
Conclusion: The factors associated with e-cigarette use were related to the students’ socioeconomic status. The roles of parents and teachers need to be addressed to reduce the harmfulness of using e-cigarettes.
أسباب النّزول وأثرها في الكشف عن المقاصد القرآنية
Authors: جلطي كنزة 
Published: March 2023

الملخص
لأسباب النزول مكانة مرموقة في منظومة الأدلّة الشرعية الخادمة للبيان القرآني والكاشفة عن مقاصده الجليلة، ولأجل تحديد موقع أسباب النزول بين مسالك الكشف عن المقاصد القرآنية، جاء هذا البحث لعرض ضوابط سبب النزول حتى يكون مسكا أصليا لا غنى عنه في تجلية المقصد القرآني، وضوابطه حتى يكون مسلكا إضافيا يُستأنس به في تحصيل القصد وتوجيهه، كما يمكن التمثيل لما ذُكر سابقا من الضوابط بالاعتماد على تقسيم العلماء للمقاصد القرآنية ، وذلك من خلال استثمار سبب النزول للكشف عن جملة من المقاصد القرآنية لم تشر إليها الآيات القرآنية مباشرة، وهذا من شأنه إثراء المنظومة المقاصدية القرآنية.