bluuebunny/crossref_metadata_2025_split huggingface dataset:
How to choose credible ensemble members for the sub-seasonal to seasonal prediction of precipitation?
Authors: Jie Weihua , Wu Tongwen , Vitart Frederic , Liu Xiangwen , Lu Yixiong , Yao Junchen , Zhao He 
Published: December 2022

AbstractThe sub-seasonal to seasonal (S2S) prediction of precipitation is not only a hot topic but also a challenge. The traditional ensemble mean and ensemble probabilistic forecast methods cannot avoid the uncertainty of the initial value in the S2S prediction. Is there a more suitable ensemble postprocessing method for the S2S prediction? In this study, the hindcast data during the 1999–2010 summers from nine operational models in the international S2S prediction project has been evaluated. Based on the quantitative objective precipitation evaluation methods, such as the Equitable Threat Score and frequency bias methods, the climatological spatio-temporal distribution of the optimal probabilistic threshold on the S2S scale is proven to exist, and it can be used as the standard to judge how many ensemble members are credible. Then, different ensemble forecast strategies are adopted in different regions to construct a Deterministic Ensemble Forecast using an Optimal Probabilistic Threshold (DEFOPT) method for precipitation prediction. The hindcast data of eight S2S models outside the period 1999–2010 are used to verify the applicability of the DEFOPT method by using the historical optimal probabilistic threshold during 1999–2010. The results show that the DEFOPT outperforms the deterministic forecast from one initial value, the ensemble mean, and the deterministic ensemble forecast using a probabilistic threshold for the occurrence days of rainfall at the 1 mm and 5 mm thresholds (≥ 1 mm and ≥ 5 mm) over China during each pentad in most S2S models.
Clinical and radiological comparison between partial and complete resection of the anterior cruciate ligament in patients with mucoid degeneration of the anterior cruciate ligament: a controlled clinical trial
Authors: Oehler N. , Haenle M. , Vogt S. , Blanke F. 
Published: December 2022

Abstract
Introduction
The pathology of a mucoid degeneration of the anterior cruciate ligament (MDACL) has been mentioned in several publications but due to its rare incidence it is not a well-known pathology. Partial or complete resection of the ACL is the option of choice after failed non-surgical treatment. However, the success rate of both surgical techniques and the subsequent risk of an ACL instability is not known. The purpose of this study was to compare the clinical and radiological outcome between partial resection and complete resection of the ACL in patients with MDACL.

Materials and methods
Patients with MDACL verified by MRI and persistent knee pain were treated by partial (Group I) or complete resection (Group II) of the ACL and were included in a controlled clinical trial after unsuccessful conservative treatment for at least 6 months. Demographic, clinical and radiological data including the thickness of ACL, ACL/intercondylar ratio, patient’s age at the time of surgery, the presenting symptoms, range of motion and ligament stability assessed by the ACL ligament score (Lachman test) were collected. In addition, Tegner activity score and Lysholm score were evaluated preoperatively and at final follow-up after a minimum of 12 months.

Results
At final follow-up with a mean of 16.8 ± 8.8 months (range 12–41; Group I: 18.3 ± 9.7 vs. Group II: 15.3 ± 8.0; ns), all patients were pain free. Postoperatively, positive Lachman tests were noted in all patients (100%) in Group II (n = 5 patients with grade II and n = 5 patients with grade III). In Group I, 8 patients (80%) showed a negative Lachman test (grade I) and 2 patients (20%) a slightly elongated Lachman test with a firm stop (grade II). The mean knee flexion at follow-up examination was 132° ± 7° (range 120°–140°; Group I: 129° ± 9° vs. Group II: 135° ± 4°; ns). In pairwise comparison, flexion angle increased significantly in both groups (Group I: p = 0.0124 and Group II: p < 0.001). Pairwise comparison of thickness of the ACL and ACL/intercondylar ratio prior to and post-surgery in Group I showed non-significant differences.

Conclusion
Both arthroscopic debridement and complete resection of the ACL lead to improvement of clinical and radiological findings in isolated MDACL. However, complete resection of the ACL will result in higher instability. Therefore, partial resection might be the better treatment option, especially in young patients with MDACL.
Numerical upscaling of parametric microstructures in a possibilistic uncertainty framework with tensor trains
Authors: Eigel Martin , Gruhlke Robert , Moser Dieter , Grasedyck Lars 
Published: December 2022

AbstractA fuzzy arithmetic framework for the efficient possibilistic propagation of shape uncertainties based on a novel fuzzy edge detection method is introduced. The shape uncertainties stem from a blurred image that encodes the distribution of two phases in a composite material. The proposed framework employs computational homogenisation to upscale the shape uncertainty to a effective material with fuzzy material properties. For this, many samples of a linear elasticity problem have to be computed, which is significantly sped up by a highly accurate low-rank tensor surrogate. To ensure the continuity of the underlying mapping from shape parametrisation to the upscaled material behaviour, a diffeomorphism is constructed by generating an appropriate family of meshes via transformation of a reference mesh. The shape uncertainty is then propagated to measure the distance of the upscaled material to the isotropic and orthotropic material class. Finally, the fuzzy effective material is used to compute bounds for the average displacement of a non-homogenized material with uncertain star-shaped inclusion shapes.
Modelling motor units in 3D: influence on muscle contraction and joint force via a proof of concept simulation
Authors: Saini Harnoor , Klotz Thomas , Röhrle Oliver 
Published: December 2022

AbstractFunctional heterogeneity is a skeletal muscle’s ability to generate diverse force vectors through localised motor unit (MU) recruitment. Existing 3D macroscopic continuum-mechanical finite element (FE) muscle models neglect MU anatomy and recruit muscle volume simultaneously, making them unsuitable for studying functional heterogeneity. Here, we develop a method to incorporate MU anatomy and information in 3D models. Virtual fibres in the muscle are grouped into MUs via a novel “virtual innervation” technique, which can control the units’ size, shape, position, and overlap. The discrete MU anatomy is then mapped to the FE mesh via statistical averaging, resulting in a volumetric MU distribution. Mesh dependency is investigated using a 2D idealised model and revealed that the amount of MU overlap is inversely proportional to mesh dependency. Simultaneous recruitment of a MU’s volume implies that action potentials (AP) propagate instantaneously. A 3D idealised model is used to verify this assumption, revealing that neglecting AP propagation results in a slightly less-steady force, advanced in time by approximately 20 ms, at the tendons. Lastly, the method is applied to a 3D, anatomically realistic model of the masticatory system to demonstrate the functional heterogeneity of masseter muscles in producing bite force. We found that the MU anatomy significantly affected bite force direction compared to bite force magnitude. MU position was much more efficacious in bringing about bite force changes than MU overlap. These results highlight the relevance of MU anatomy to muscle function and joint force, particularly for muscles with complex neuromuscular architecture.
Acute stress response on Atlantic salmon: a time-course study of the effects on plasma metabolites, mucus cortisol levels, and head kidney transcriptome profile
Authors: Madaro Angelico , Nilsson Jonatan , Whatmore Paul , Roh HyeongJin , Grove Søren , Stien Lars H. , Olsen Rolf Erik 
Published: December 2022

Abstract
Farmed Atlantic salmon (Salmo salar) welfare and performance can be strongly influenced by stress episodes caused by handling during farming practices. To better understand the changes occurring after an acute stress response, we exposed a group of Atlantic salmon parr to an acute stressor, which involved netting and transferring fish to several new holding tanks. We describe a time-course response to stress by sampling parr in groups before (T0) and 10, 20, 30, 45, 60, 120, 240, 300, and 330 min post-stress. A subgroup of fish was also subjected to the same stressor for a second time to assess their capacity to respond to the same challenge again within a short timeframe (ReStressed). Fish plasma was assessed for adrenocorticotropic hormone (ACTH), cortisol, and ions levels. Mucus cortisol levels were analyzed and compared with the plasma cortisol levels. At 5 selected time points (T0, 60, 90, 120, 240, and ReStressed), we compared the head kidney transcriptome profile of 10 fish per time point. The considerably delayed increase of ACTH in the plasma (60 min post-stress), and the earlier rise of cortisol levels (10 min post-stress), suggests that cortisol release could be triggered by more rapidly responding factors, such as the sympathetic system. This hypothesis may be supported by a high upregulation of several genes involved in synaptic triggering, observed both during the first and the second stress episodes. Furthermore, while the transcriptome profile showed few changes at 60 min post-stress, expression of genes in several immune-related pathways increased markedly with each successive time point, demonstrating the role of the immune system in fish coping capacity. Although many of the genes discussed in this paper are still poorly characterized, this study provides new insights regarding the mechanisms occurring during the stress response of salmon parr and may form the basis for a useful guideline on timing of sampling protocols.
It is still about bureaucracy in German faculties
Authors: Hagerer Ilse 
Published: December 2022

AbstractOne of the main discussions in higher education is whether universities have appropriately adapted their structures and processes in response to the New Public Management (NPM) reforms and the Bologna Process. There are no profound empirical investigations on the extent to which faculties take elements of the reforms into account in terms of administrative processes and organizational structure dimensions according to the bureaucracy approach. This article examines how German faculty managers perceive bureaucratization processes by evaluating organizational structure dimensions. For this, we interpret interviews with 16 experts of German faculties through qualitative content analysis to extract in-depth manifestations of these dimensions. Our results show that the dimensions formalization, standardization, specialization, configuration, internal support functions, team self-coordination, and (de)centralization reflect elements of the NPM and Bologna reforms in the perception of faculty staff. These dimensions are complemented by decoupling mechanisms, i.e., discrepancies between formal structure and common practice, which hinder reform implementation. Besides, we identify elements of post-NPM approaches like network governance and neo-Weberianism supplementing reform implementation. We highlight (dys)functional effects of the dimensions by assessing them with criteria of effectiveness. Our results foster a deeper understanding of faculty organization by demonstrating levels of bureaucratization using profound examples of the interviewed persons.
From tablet to table: How augmented reality influences food desirability
Authors: Fritz William , Hadi Rhonda , Stephen Andrew 
Published: December 2022

Abstract
Augmented reality (AR) technology has generated enormous industry investment and buzz, with the food and beverage sector quickly embracing this technology in an effort to enhance the customer experience. However, academic research has only just begun to empirically explore how and why this technology might influence consumer judgements and behaviors in such contexts. Across two field studies involving consequential behavior and two controlled laboratory studies, we find that AR’s unique ability to visually superimpose objects onto a real-time environment increases consumers’ ability to mentally simulate consuming a pictured food, which in turn increases their desire and purchase likelihood of the food item. Further, we find the increased mental simulation produced by AR is itself preceded and driven by an increased sense of personal relevance of the food items.
Adherence to glucose monitoring with intermittently scanned continuous glucose monitoring in patients with type 1 diabetes
Authors: Sousa Carolina , Neves João Sérgio , Dias Cláudia Camila , Sampaio Rute 
Published: December 2022

Abstract
Purpose
This study aims to predict the Intermittently scanned continuous glucose monitoring (isCGM) adherence behavior of patients with Type 1 Diabetes.

Methods
Patients with Type 1 Diabetes mellitus using FreeStyle Libre™ System (FL), a isCGM device, that attended the “Insulin Infusion Pump clinic” at Centro Hospitalar de São João were enrolled and evaluated for sociodemographic and clinical characterization, beliefs and concerns about Diabetes Mellitus, as well as isCGM’s perceptions. Intermittently scanned continuous glucose monitoring data were collected to characterize monitoring patterns and to measure isCGM’s adherence—FL average of scans/day.

Results
Seventy-two patients with a mean of 30.36 years (sd=11.35) participate in this study. A median of 7 scans/day was performed. The adherence predictors found was Age (β = 0.191, p = 0.006), Time in target (β = 0.530, p = 0.002), isCGM Necessity (β = 2.631, p = 0.048), Body Mass Index (β = −0.549, p = 0.017) and Sex (β = −3.996; p = 0.011).

Conclusions
This study emphasizes the relevance of glucose monitoring adherence in disease control and shows that males of younger ages, presenting with higher body mass index levels, lower time in target, and reporting lower isCGM necessity are less adherent to isCGM. Therefore, these patients should be closely followed and object of personalized strategies to promote treatment adherence.
Inhibition of the Glycolysis Prevents the Cerebral Infarction Progression Through Decreasing the Lactylation Levels of LCP1
Authors: Zhang Wei , Xu Liang , Yu Zhenfei , Zhang Meiqi , Liu Jingquan , Zhou Jianming 
Published: December 2022

AbstractCerebral infarction (CI), also known as ischemic stroke, has a high incidence rate and mortality rate. The purpose of this study was to investigate the potential effect and mechanism of Lymphocyte cytosolic protein 1 (LCP1) in the CI progression. The middle cerebral artery occlusion (MCAO) treated rats and oxygen–glucose deprivation/reoxygenation (OGD/R) stimulated PC12 cells were used to establish CI model in vivo and in vitro. The cell proliferation and apoptosis was determined by CCK-8 assay and flow cytometry, respectively. Immunoprecipitation and western blot was performed to test the lactylation levels of LCP1. The cells were treated with cycloheximide to determined the protein stability of LCP1. The glucose uptake and lactate production was determined with commercial kits. The extracellular acidification rate were evaluated by Seahorse. The results showed that LCP1 was upregulated in the MCAO rats and OGD/R stimulated PC12 cells. LCP1 knockdown dramatically decreased the neurological score, infarct volume and the brain water content of MCAO rats. Besides, LCP1 knockdown promoted the cell viability while decreased the apoptosis rate of the OGD/R stimulated PC12 cells. Additionally, the global lactylation and lactylation levels of LCP1 was prominently enhanced in vivo and in vitro in cerebral infarction. 2-DG treatment prominently decreased it. In conclusion, inhibiting the glycolysis decreased the lactylation levels of LCP1 and resulted in the degradation of LCP1, which eventually relieved the CI progression.
Neurodynamical Computing at the Information Boundaries of Intelligent Systems
Authors: Monaco Joseph D. , Hwang Grace M. 
Published: December 2022

AbstractArtificial intelligence has not achieved defining features of biological intelligence despite models boasting more parameters than neurons in the human brain. In this perspective article, we synthesize historical approaches to understanding intelligent systems and argue that methodological and epistemic biases in these fields can be resolved by shifting away from cognitivist brain-as-computer theories and recognizing that brains exist within large, interdependent living systems. Integrating the dynamical systems view of cognition with the massive distributed feedback of perceptual control theory highlights a theoretical gap in our understanding of nonreductive neural mechanisms. Cell assemblies—properly conceived as reentrant dynamical flows and not merely as identified groups of neurons—may fill that gap by providing a minimal supraneuronal level of organization that establishes a neurodynamical base layer for computation. By considering information streams from physical embodiment and situational embedding, we discuss this computational base layer in terms of conserved oscillatory and structural properties of cortical-hippocampal networks. Our synthesis of embodied cognition, based in dynamical systems and perceptual control, aims to bypass the neurosymbolic stalemates that have arisen in artificial intelligence, cognitive science, and computational neuroscience.
3D-modellen gebaseerd op prostaat-MRI beïnvloeden de planning van zenuwsparing bij robotgeassisteerde radicale prostatectomie
Authors: Veerman Hans , Boellaard Thierry N. , van der Eijk Jari A. , Sluijter Judith H. , Roeleveld Ton A. , van der Sluis Tim M. , Nieuwenhuijzen Jakko A. , Wit Esther , van Alphen Maarten J. A. , van Veen Robert L. P. , Vis André N. , van der Poel Henk G. , van Leeuwen Pim J. 
Published: December 2022

SamenvattingDoel van deze studie was de klinische toepasbaarheid van 3D-modellen onderzoeken in de preoperatieve planning van robotgeassisteerde radicale laparoscopische prostatectomie (RALP). Er werden 20 virtuele 3D-modellen en 3D-prints gemaakt, waarna 7 urologen op basis hiervan de mate van zijdespecifieke zenuwsparing bepaalden. Vervolgens werden de mate van zenuwsparing per zijde per modaliteit en de absolute overeenkomst in de geplande zenuwsparing tussen urologen geanalyseerd, waaruit bleek dat er tussen de urologen een klinisch-relevant verschil was in de mate van preoperatieve zijdespecifieke zenuwsparing tussen MRI en de virtuele modellen en MRI en de 3D-prints in 25 en 26% van de gevallen met een intraclasscorrelatiecoëfficient van 0,40 (95%-BI 0,28–0,55) voor MRI, van 0,52 (0,39–0,66) voor virtuele 3D-modellen en van 0,58 (0,45–0,71) voor 3D-prints. De conclusie is dat de 3D-modellen een klinisch-relevante impact hebben op de preoperatieve planning van zenuwsparing bij RALP.
Fruit Peel Soil Supplementation Induces Physiological and Biochemical Tolerance in Schefflera arboricola L. Grown Under Heat Conditions
Authors: El-Serafy Rasha S. , El-Sheshtawy Abdel-Nasser A. , Dahab Abeer A. 
Published: December 2022

AbstractSchefflera plant is propagated and grown under greenhouse cultivation, and most of these greenhouses are low-cost. In the summer, the heat generated in greenhouses becomes a limiting factor for plant growth and, subsequently, limits the production of high-quality species under greenhouse conditions. The powder of banana (B), orange (O), and pomegranate (P) peels and their combinations were added as soil supplementation at rates of 8 and 16 g/pot to the pots of Schefflera plants, which were grown during the summer season under a low-cost greenhouse. The growth analysis was estimated after 150 and 180 days from planting. Heat conditions significantly inhibited the relative growth rate, crop growth rate, and absolute growth rate (AGR) of Schefflera plants, but fruit peel applications were shown to markedly mitigate its negative impact. Fruit peel applications augmented the shoot and root growth rates and leaf pigments, decreased AGR reduction, promoted relative water content, increased membrane stability index (MSI), and alternated the phenotypic plasticity index (PPI). Fruit peels significantly increased total phenol and flavonoid levels as well as the antioxidant activity (DPPH), which positively alleviated the oxidative damage (decreased H2O2 and MDA contents) that occurred in plant leaves, and induced heat-shock protein synthesis, leading to plants with greater heat tolerance. Orange peel application at the rate of 16 g/pot to the potting soil is more beneficial for root initiation and development during the early phases of Schefflera plant life, as well as more effective in increasing the aerial portions and inducing resistance to heat conditions in low-cost polyethylene greenhouses.
Application of a simple model for ice growth to the Lake St. Moritz, Switzerland
Authors: Oerlemans Johannes , Keller Felix 
Published: December 2022

AbstractWe present a Simple Lake Ice Model to calculate the growth rate of lake ice in a cold and relatively dry climate. The focus is on Lake St. Moritz, Switzerland, which has an area of 0.78 km2and is about 45 m deep. In winter the lake is extensively used for recreational purposes, including horse racing with thousands of spectators. Safety on the ice cover is essential, and there is a great need to have a simple tool with which the growth rate of the ice layer can be calculated for given meteorological conditions. The approach is based on a simple formulation of the upper temperature of the ice layer, which depends on air temperature and snow cover. Input data are the date on which the lake freezes over, daily mean air temperatures and snow depth. For the winter 2021/22 calculated ice growth compares well with ice thickness measurements. We demonstrate that grooming of the snow has a significant positive effect on the ice thickening rate. We also evaluate the sensitivity of the simulated ice thickness to increasing mean temperature.
Climate Change: Bad News for Populism? How the Rassemblement National Used COVID-19 to Promote Its Environmental Agenda
Authors: de Nadal Lluis 
Published: December 2022

AbstractThis article uses the French Rassemblement National (RN) as a case study to examine how the populist radical right (PRR) prepares for a world after COVID-19 dominated by climate change concerns. Research suggests that certain measures introduced to contain the virus – such as the establishment of strict border and travel restrictions – may legitimize the PRR’s protectionist and anti-immigration agendas, yet few have examined whether or how PRR parties have used COVID-19 to promote their environmental agenda. If anything, the expectation has been that the pandemic would hurt the PRR precisely because its effects, unlike climate change, cannot be dismissed as a “hoax.” This view overlooks not only the “environmental turn” recently taken by several PRR parties but also the possibility that public awareness of the causal link between climate change and COVID-19 may work to their advantage. The analysis presented in this article highlights this possibility, showing that the RN used COVID-19 not only to capitalize on anti-immigrant sentiment but also to bolster its self-image as a champion of environmental protection.