bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion—Initial Case Series Investigating Safety and Efficacy
Authors: Tabarestani Troy Q. , Sykes David A. W. , Maquoit Gisselle , Wang Timothy Y. , Ayoub Chakib M. , Shaffrey Christopher I. , Wiggins Walter F. , Abd-El-Barr Muhammad M. 
Published: January 2023

BACKGROUND:
For percutaneous lumbar fusion (percLIF), magnetic resonance imaging and computed tomography are critical to defining surgical corridors. Currently, these scans are performed separately, and surgeons then use fluoroscopy or neuromonitoring to guide instruments through Kambin's triangle. However, anatomic variations and intraoperative positional changes are possible, meaning that safely accessing Kambin's triangle remains a challenge because nerveroot visualization without endoscopes has not been thoroughly described.

OBJECTIVE:
To overcome the known challenges of percLIF and reduce the likelihood of iatrogenic injuries by showing real-time locations of neural and bony anatomy.

METHODS:
The authors demonstrate an intraoperative navigational platform that applies nerve root segmentation and image fusion to assist with percLIF. Five patients from a single institution were included.

RESULTS:
Of the 5 patients, the mean age was 71 ± 8 years and 3 patients (60%) were female. One patient had general anesthesia while the remaining 4 patients underwent awake surgery with spinal anesthesia. The mean area for the L4-L5 Kambin's triangle was 76.1 ± 14.5 mm2. A case example is shown where the side of approach was based on the fact that Kambin's triangle was larger on one side compared with the other. The mean operative time was 170 ± 17 minutes, the mean blood loss was 32 ± 16 mL, and the mean hospital length of stay was 19.6 ± 8.3 hours. No patients developed postoperative complications.

CONCLUSION:
This case series demonstrates the successful and safe application of nerve segmentation using magnetic resonance imaging/computed tomography fusion to perform percLIF and provide positive patient outcomes.
Extracranial Jugular Foramen Schwannomas Treated with the Extreme Lateral Juxtacondylar Approach: Surgical Technique and Our Experience
Authors: Di Vitantonio Hambra , Tozzi Alessandro , De Paulis Danilo , Millimaggi Daniele F. , Di Cola Francesco , Raysi Dehcordi Soheila , Galzio Renato J. , Ricci Alessandro 
Published: January 2023

BACKGROUND:
Schwannoma that arises in the jugular foramen (JF) represents an important challenge for neurosurgeons for its precise location, extension, and neurovascular relationship. Nowadays, different managements are proposed. In this study, we present our experience in the treatment of extracranial JF schwannomas (JFss) with the extreme lateral juxtacondylar approach (ELJA).

OBJECTIVE:
To present our experience in the treatment of extracranial JF schwannomas (JFss) with the ELJA.

METHODS:
Between January 2013 and January 2017, 12 patients with extracranial JFs underwent surgery by ELJA. All lesions were type C of the Samii classification. Indocyanine green videoangiography was used to evaluate the relationship between the internal jugular vein and the tumor and to control the presence of spasm in the vertebral artery.

RESULTS:
A complete exeresis was achieved in 9 patients while in 3 patients, it was subtotal. The complete regression of symptoms was obtained in 7 patients with a total resection. The remaining cases experienced a persistence of symptoms.

CONCLUSION:
The success of this surgery is achieved through a management that starts from the patient's position. We promote an accurate evaluation of JFs through the Samii classification: Type C tumors allow the use of ELJA that reduces surgical complications. Furthermore, we recommend the use of indocyanine green videoangiography to preserve the vessels and prevent vasospasm.
Giant Pediatric Dural Arteriovenous Fistula Management using a Combined Operative Approach in a Hybrid Neuroendovascular Surgery Suite: Technical Nuances and Review of Literature
Authors: Saway Brian Fabian , Porto Guilherme B. F. , Sattur Mithun G. , Domingo Ricardo A. , Triano Matthew , Al Kasab Sami , Eskandari Ramin , Lena Jonathan R. 
Published: January 2023

BACKGROUND:
Pediatric intracranial dural arteriovenous fistulas (dAVFs) are rare, complex entities usually presenting with macrocephaly from increased intracranial pressures at a young age. In the setting of a symptomatic intracranial dAVF that has undergone multiple endovascular treatments with subsequent recurrence or failed embolization attempts, the intracranial venous system can become inaccessible by traditional transvenous and transarterial routes. Direct puncture of the venous sinus for endovascular access after surgical exposure is a viable option.

OBJECTIVE:
To describe the technical nuances and available literature for direct puncture of the venous sinus for endovascular access in a pediatric patient with dAVF.

METHODS:
The clinical characteristics were reviewed and reported for a patient who underwent direct puncture of the venous sinus for endovascular access. In addition, a literature review was conducted for relevant literature pertaining to this technique and its associated indications, outcomes, and complications.

RESULTS:
Only 2 other reports of direct puncture of venous sinus for endovascular access after surgical exposure were found in the literature. Our patient achieved a favorable outcome with complete dAVF obliteration.

CONCLUSION:
Direct puncture of the venous sinus for endovascular access after surgical exposure for complex dAVFs that are inaccessible by transvenous or transarterial routes is a practical and safe approach to intracranial venous access that should be part of the vascular neurosurgeon's arsenal.
The Rationale Behind Transcirculation Neuroendovascular Interventions: Literature Review Through a Case-Series Approach
Authors: Colasurdo Marco , Edhayan Gautam , Al Taweel Alaha , Barghash Maggie , Kan Peter , Raghuram Karthikram 
Published: January 2023

BACKGROUND:
With the development of advanced endovascular techniques and materials, neurointerventionalists can perform challenging and complex cases that were previously difficult to perform. Transcirculation approaches could be a useful tool used in complicated cases, providing access to the target vessel, through the contralateral or opposite circulation, when anterograde access is difficult or nonachievable.

OBJECTIVE:
To retrospectively review cerebrovascular interventions performed through a transcirculation approach performed by staff at our Institution.

METHODS:
English-language studies, published until August 2022, reporting transcirculation interventions in the cerebrovascular circulation were retrospectively collected. Type of intervention, number of cases, rationale, and complications were analyzed. Furthermore, similar cases performed by staff currently at our institution were also reviewed and described.

RESULTS:
Including our cases, a total of 273 transcirculation treatment approaches have been reported. Intracranial aneurysm embolization, stroke thrombectomies, intra-arterial ophthalmic chemotherapy, arteriovenous malformationss, arteriovenous fistulas embolizations, and intracranial angioplasty and stenting are common indications. Reason for using a retrograde approach were stent/balloon–assisted coiling of wide neck aneurysm in 116 cases, difficult angulation of branch in 91 cases, occlusion of parent vessel in 55 cases, and bailout/other in 11 cases.

CONCLUSION:
Transcirculation approaches can be considered for cases where conventional anterograde treatment options are not feasible or as a bailout strategy in failed or complicated treatment attempts. They represent a strategy to consider when facing challenging cases, and if performed by experienced and dedicated neurointerventionalists, they can represent a safe alternative.
Trigeminal Sensory Neuropathy Predicts Chemosensory Dysfunction After Skull Base Surgery
Authors: Podlesek Dino , Chao Yun-Ting , Weitkamp Frederike , Schackert Gabriele , Hummel Thomas 
Published: January 2023

BACKGROUND:
Trigeminal sensory neuropathy, characterized by diminished or exaggerated/painful sensation along the distribution of trigeminal branches, is one of the complications after skull base surgery. These procedures can also affect chemosensory functions and compromise the patients' quality of life.

OBJECTIVE:
To examine those postoperative complications in chemosensory and facial cutaneous sensory functions as well as their interaction.

METHODS:
A total of 61 patients being operated for various pathologies in the vicinity of trigeminal pathway (17 with trigeminal neuralgia, 20 with meningiomas, and 24 with vestibular schwannomas) and 50 healthy controls were enrolled in this case-control study. Postoperative trigeminal neuropathic symptoms were evaluated. The olfactory, gustatory, and intranasal trigeminal functions were assessed using the Sniffin’ Stick olfactory test, lateralized taste strip test, and the lateralized intranasal trigeminal CO2 detection thresholds, respectively.

RESULTS:
Patients with trigeminal neuralgia and meningioma had relatively decreased olfactory function, whereas those with vestibular schwannoma had a relative decrease in taste function. As for the relationship between the distribution of trigeminal neuropathy and chemosensory dysfunction, we found that V3 involvement predicted lower side-specific taste function. In addition, V2/V3 involvement predicted relatively lower side-specific intranasal trigeminal function.

CONCLUSION:
The present results suggest a differential involvement of the chemical senses in relation to the site and pathology of the lesions after surgery. The presence of trigeminal neuropathy is associated with taste and intranasal trigeminal dysfunction. The results serve as a basis for consultation regarding outcome prediction and patient education.
Kashimé: A Novel Knotless Surgical Suture to Simplify Dural Stitches in Endoscopic Transnasal Surgery
Authors: Hasegawa Hirotaka , Shinya Yuki , Ono Minoru , Kikuta Shu , Kondo Kenji , Saito Nobuhito 
Published: January 2023

BACKGROUND:
Dural suturing is an effective adjunct to skull base dural repair in endoscopic transnasal surgery, although it is technically cumbersome. Here, we presented a novel surgical suture “Kashimé” (Kono Seisakusho) that can be tightened without tying.

OBJECTIVE:
To examine the efficacy of Kashimé for skull base dural repair in endoscopic transnasal surgery.

METHODS:
Kashimé was used in 8 patients with skull base dural defects during nonpedicled flap-based multilayered skull base reconstruction to close or approximate the gaps between the dural edges or secure a free fascial graft. The time required for each dural stitch (passing a needle through the dura, pulling out the thread, and tightening it) and the incidence of postoperative cerebrospinal fluid leakage were the study end points.

RESULTS:
Based on our preliminary experiences with 12 stitches used, no postoperative cerebrospinal fluid leakage was observed. The learning curve was steep, and the mean (±SD) time was 127 (±44) seconds for a single stitching procedure, except for the first case. Regarding the metal artifact, although a beam hardening artifact was not observed on computed tomography, a 4- to 9-mm diameter image defect was observed on magnetic resonance imaging.

CONCLUSION:
Kashimé can help surgeons to complete a single dural stitch in endoscopic transnasal surgery for approximately 2 minutes. It may be an optimal tool for skull base reconstruction, but the efficacy and safety need to be investigated.
Newly Diagnosed Adult Basal Ganglia Gliomas Treated With Laser Interstitial Thermal Therapy: A Comparative Cohort With Needle Biopsy
Authors: Merenzon Martín A. , Patel Nitesh V. , Morell Alexis A. , Marcó del Pont Francisco , Moll Joshua M. , Komotar Ricardo J. , Ivan Michael E. 
Published: January 2023

BACKGROUND:
Few cytoreductive surgical tools are available for newly diagnosed basal ganglia gliomas. Current reports showed high associated morbidity and mortality. Given their deep localization, laser interstitial thermal therapy (LITT) is still a rare indication. Moreover, few reports account for which of the available options have better outcomes.

OBJECTIVE:
To retrospectively analyze our experience with LITT and compare its safety, feasibility, and efficacy with needle biopsy for the management of adult basal ganglia gliomas.

METHODS:
Twenty-two patients with gliomas from the midline (e.g. thalamus and lenticular nucleus) managed with either LITT/biopsy or needle biopsy from 2015 to 2021 were included. Records regarding location, diagnosis, Karnofsky Performance Score, length of hospital stay, preoperative lesion and ablation volume, perioperative complications, and data of adjuvant treatment were collected. Overall survival was evaluated with Kaplan-Meier analysis.

RESULTS:
Seven patients had LITT, and 15 underwent biopsy. The overall mean age was 60.9 years (25-82 years). The average tumor volume in the former was 16.99 cm3 and 17.65 cm3 in the latter. No postsurgical complications were found in the LITT group, and 1 patient had a postsurgical hemorrhage after biopsy. The mean overall survival was 20.28 ± 9.63 months in the LITT group, which was greater but not statistically significant than in the biopsy group (13.85 ± 4.48 months; P = .78).

CONCLUSION:
Our results show that laser ablation may be both feasible and safe in adult basal ganglia gliomas. Given the lack of safe cytoreductive treatment options, LITT should be considered as a valid choice for these patients.
Surgical Closure of the Eustachian Tube Through Middle Fossa and Transmastoid Approaches: A Pilot Cadaveric Anatomy Study
Authors: Staarmann Brittany , Palmisciano Paolo , Hoz Samer S. , Doyle Edward J. , Forbes Jonathan A. , Samy Ravi N. , Zuccarello Mario , Andaluz Norberto 
Published: January 2023

BACKGROUND:
Cerebrospinal fluid rhinorrhea after temporal bone surgery involves drainage from the Eustachian tube (ET) into the nasopharynx, causing significant patient morbidity. Variable anatomy of the ET accounts for failures of currently used ET obliteration techniques.

OBJECTIVE:
To describe the surgical anatomy of the ET and examine possible techniques for ET closure through middle fossa (MF) and transmastoid approaches.

METHODS:
We described the surgical anatomy of the ET from the MF and transmastoid approaches in 5 adult cadaveric heads, measuring morphometric and surgical anatomy parameters and establishing targets for definite ET obliteration.

RESULTS:
The osseous ET measured an average of 19.53 mm (±1.56 mm), with a mean diameter of 2.24 mm (±0.29 mm). The shortest distance between the greater superficial petrosal nerve and the ET junction was 6.61 mm (±0.61 mm). Shortest distances between the ET junction and the foramen spinosum and posterior border of the foramen ovale were 1.09 mm (±0.24 mm) and 2.03 mm (±0.30 mm), respectively. Closure of the cartilaginous ET may be performed by folding it in on itself, securing it by packing, suturing, or surgical clip ligation.

CONCLUSION:
Definite obliteration of the cartilaginous ET appears feasible and the most definite approach to eliminate egress of cerebrospinal fluid to the nasopharynx using the MF approach. This technique may be used as an adjunct to skull base procedures where ET closure is planned.
Transradial Versus Transfemoral Intraoperative Cerebral Angiography for Open Cerebrovascular Surgery: Effectiveness, Safety, and Learning Curve
Authors: Hendrix Philipp , Melamed Itay , Weiner Gregory M. , Goren Oded , Griessenauer Christoph J. , Schirmer Clemens M. 
Published: January 2023

BACKGROUND:
Intraoperative cerebral angiography (IOA) is a valuable adjunct in open and hybrid cerebrovascular surgery. Commonly, transfemoral access (TFA) is used. Lately, transradial access (TRA) has gained popularity for neurointervention. However, the TRA has not yet been compared with the TFA for IOA.

OBJECTIVE:
To compare the effectiveness and safety of the TRA and TFA for IOA. In addition, the learning curve for implementing the TRA for IOA was evaluated.

METHODS:
Between July 2020 and 2022, 92/1787 diagnostic cerebral angiographies met inclusion criteria for IOA. Sheath run time to primary target vessel run time (STT), amount of contrast dye (CD), fluoroscopy time (FT), and dose–area products (DAPs) were compared between TRA and TFA, different aortic arch types, and both study years.

RESULTS:
One case required transitioning from TRA to TFA (1/26, 3.8%) because of a minute proximal radial vasculature. The STT, CD, FT, and DAP were similar for the TRA (n = 25) and the TFA groups (n = 67) (p = ns). One groin hematoma (1.5%) was observed in the TFA group. No other complications or any change in modified Rankin Scale were observed. Aortic arch type II/III was associated with longer STT (P = .032) but not CD, FT, or DAP. There was a nonsignificant decline of STTs among the TRA cases (P = .104) but stable STTs among TFA cases (P = .775).

CONCLUSION:
The TRA and TFA represent equally effective and safe routes for IOA. In addition, expertise with the TRA can rapidly be gained and facilitates tailoring the access for IOA to patient's individual anatomy and surgeon's needs.
Lower-level predictors and behavioral correlates of maximal aerobic capacity and sprint speed among individual lizards
Authors: Albuquerque Ralph L. , Zani Peter A. , Garland Theodore 
Published: January 2023

ABSTRACTThe standard paradigm of organismal biology views lower-level traits (e.g. aspects of physiology) as determining organismal performance ability (e.g. maximal sprint speed), which in turn constrains behavior (e.g. social interactions). However, few studies have simultaneously examined all three levels of organization. We used focal observations to record movement behaviors and push-up displays in the field for adult male Sceloporus occidentalis lizards during the breeding season. We then captured animals, measured aspects of their physiology, morphology and performance, and counted ectoparasites and endoparasites as potential predictors of sprint speed and maximal oxygen consumption (V̇O2,max). Field behaviors were statistically repeatable, but not strongly so. Sprint speed and V̇O2,max were repeatable using residuals from regressions on body mass (speed: r=0.70; V̇O2,max: r=0.88). Both calf [standardized partial regression (path) coefficient B=0.53] and thigh [B=−0.37] muscle mass (as residuals from regressions on body mass) were significant predictors of sprint speed; hemoglobin concentration (B=0.42) was a predictor of V̇O2,max. In turn, V̇O2,max predicted the maximum number of four-legged push-ups per bout (B=0.39). In path analysis, log likelihood ratio tests indicated no direct paths from lower-level traits to behavior, supporting the idea that morphology, in the broad sense, only affects behavior indirectly through measures of performance. Our results show that inter-individual variation in field behaviors can be related to performance ability, which in turn reflect differences in morphology and physiology, although not parasite load. Given the low repeatability of field behaviors, some of the relationships between behavior and performance may be stronger than suggested by our results.
Increased reliance on coronary perfusion for cardiorespiratory performance in seawater-acclimated rainbow trout
Authors: Wallbom Nicklas , Zena Lucas A. , McArley Tristan J. , Ekström Andreas , Axelsson Michael , Gräns Albin , Sandblom Erik , Morgenroth Daniel 
Published: January 2023

ABSTRACTSalmonid ventricles are composed of spongy and compact myocardium, the latter being perfused via a coronary circulation. Rainbow trout (Oncorhynchus mykiss) acclimated to sea water have higher proportions of compact myocardium and display stroke volume-mediated elevations in resting cardiac output relative to freshwater-acclimated trout, probably to meet the higher metabolic needs of osmoregulatory functions. Here, we tested the hypothesis that cardiorespiratory performance of rainbow trout in sea water is more dependent on coronary perfusion by assessing the effects of coronary ligation on cardiorespiratory function in resting and exhaustively exercised trout acclimated to fresh water or sea water. While ligation only had minor effects on resting cardiorespiratory function across salinities, cardiac function after chasing to exhaustion was impaired, presumably as a consequence of atrioventricular block. Ligation reduced maximum O2 consumption rate by 33% and 17% in fish acclimated to sea water and fresh water, respectively, which caused corresponding 41% and 17% reductions in aerobic scope. This was partly explained by different effects on cardiac performance, as maximum stroke volume was only significantly impaired by ligation in sea water, resulting in 38% lower maximum cardiac output in seawater compared with 28% in fresh water. The more pronounced effect on respiratory performance in sea water was presumably also explained by lower blood O2 carrying capacity, with ligated seawater-acclimated trout having 16% and 17% lower haemoglobin concentration and haematocrit, respectively, relative to ligated freshwater trout. In conclusion, we show that the coronary circulation allows seawater-acclimated trout to maintain aerobic scope at a level comparable to that in fresh water.
Parasitoid wasp venom re-programs host behavior through downmodulation of brain central complex activity and motor output
Authors: Rana Amit , Adams Michael E. , Libersat Frederic 
Published: January 2023

ABSTRACT
The parasitoid wasp Ampulex compressa hunts down its host, the American cockroach (Periplaneta americana), and envenomates its brain to make it a behaviorally compliant food supply for its offspring. The primary target of the wasp sting is a locomotory command center called the central complex (CX). In the present study, we employ, for the first time, chronic recordings of patterned cockroach CX activity in real time as the brain is infused with wasp venom. CX envenomation is followed by sequential changes in the pattern of neuronal firing that can be divided into three distinct temporal phases during the 2 h interval after venom injection: (1) reduction in neuronal activity for roughly 10 min immediately after venom injection; (2) rebound of activity lasting up to 25 min; (3) reduction of ongoing activity for up to 2 h. Long-term reduction of CX activity after venom injection is accompanied by decreased activity of both descending interneurons projecting to thoracic locomotory circuitry (DINs) and motor output. Thus, in this study, we provide a plausible chain of events starting in the CX that leads to decreased host locomotion following brain envenomation. We propose that these events account for the onset and maintenance of the prolonged hypokinetic state observed in stung cockroaches.
Soy-Flour Adhesive Bonding of Low-Moisture Hickory and Red Oak Veneer
Authors: Wykle Cody J. , Zink-Sharp Audrey 
Published: January 2023

Abstract
The goal of this research was to test the effect of low-moisture-content veneer on the strength and durability of plywood test specimens constructed with a soy-flour adhesive. Soy-flour adhesive systems offer certain environmental and health advantages but research studies and performance data are lacking currently for a variety of wood types and end uses. Soyad adhesive was used in this study due to its natural, renewable soy flour, a novel cross-linking resin, and lack of added formaldehyde. Test specimens were prepared using heartwood of hickory and red oak and sapwood of hickory. These wood types were used to represent some of the most challenging wood adhesion conditions. Analytical tests included determination of select chemical properties of the adhesive and wood veneer, measurement of strength properties of the adhesive bond, and assessment of delamination tendencies of bonded panels following water soaking.