bluuebunny/crossref_metadata_2025_split huggingface dataset:
The tension–tension fatigue behavior of carbon fiber/epoxy woven composites with stable structural reinforcements
Authors: Ma Zhenyu , Ma Wensuo , Man Ruidong , Jia Chenhui , Ma Zhenhao , Xu Yonghao 
Published: February 2023

AbstractCarbon fiber/epoxy woven composites with stable structural reinforcements exhibit a better static mechanical property than composites with unstable reinforcements. The stable structural reinforcements show a limited deformation during the curing process. To investigate the influence of reinforcements on the tension–tension fatigue properties of composites, three typical composite samples were manufactured and experiment research was developed. The results show that the composites with stable structural reinforcements prove excellent fatigue behavior, and the initial elastic modulus can be enhanced. The curvature of load‐bearing yarns affected the loading capacity, and the low curvature improve the structural integrity. The unstable structural reinforcements lead to the “fatigue strengthening” after a limited number of cycles, owing to the straightening of load‐bearing yarns. Reducing the curvature of yarns can effectively decrease the occurrence of initial cracks by altering the structural characteristics of reinforcements, which strengthens the bonding to improve fatigue resistance.
Women's informal entrepreneurship through the lens of institutional voids and institutional logics
Authors: Ejaz Lalarukh , Grinevich Vadim , Karatas‐Ozkan Mine 
Published: February 2023

AbstractIn this conceptual paper, we respond to the calls for broader theoretical approaches that can coherently demonstrate a high degree of conceptual sensitivity to multiple combinations of institutional factors influencing women's informal entrepreneurship (WIE) and related agency. We do so by integrating constructs of gender and gender inequality with those of institutional logics and institutional voids. We find that a refined understanding of institutional voids is required to pave the way for a meaningful theoretical integration and empirical application of the related conceptualizations. We offer such a revised definition by placing formal and informal logics (rather than institutions) at the heart of it. In our theorizing, we propose that gender interplaying with formal and informal institutional logics create varying degrees of obscure and unique institutional voids that shape WIE prevalence. The proposed harmonized theoretical lens provides researchers with flexible yet consistent guidance for conducting context‐specific empirical work that can coherently advance understanding of underlying logics shaping WIE and related agency.
Mistakes in the diagnosis and treatment of Helicobacter pylori infection in daily clinical practice
Authors: Ariño‐Pérez Inés , Martínez‐Domínguez Samuel J. , Alfaro Almajano Enrique , Carrera‐Lasfuentes Patricia , Lanas Ángel 
Published: February 2023

AbstractBackgroundAn adequate diagnostic and therapeutic approach to Helicobacter pylori (H. pylori) infection is the cornerstone to avoid overdiagnosis, overuse of health resources, and increase in antibiotic resistances. The aim of the study was to evaluate the most common errors in clinical practice and the associated risk factors.Materials and MethodsThis is a retrospective observational study including patients with H. pylori infection and no previous treatment belonging to two defined areas of the National Health System in Spain; some of them were enrolled in the European Registry on H. pylori management (Hp‐EuReg). Patients were attended by gastroenterologists between 2010 and 2019. According to current guidelines, we evaluated indications for H. pylori investigation, appropriateness of diagnostic test used in dyspeptic patients and discontinuation of surveillance after treatment.ResultsA total of 1730 patients were included, receiving 2260 eradication regimens. H. pylori infection was investigated in 1.7% cases in absence of a formal indication. Oral endoscopy was incorrectly used in 56% of patients with dyspepsia under 55 years without alarm signs, and urea breath test (UBT) was incorrectly used in 22.4% of patients with dyspepsia ≥55 years or red flags. Levofloxacin containing regimens were used as first‐line therapy in 7.5% of non‐allergic to penicillin patients. After first‐line failure, clarithromycin was repeated in 2.6% of the patients who received second‐line therapy. Confirmatory test of H. pylori status was absent in 2.5% cases. Men, patients under 55 years, and patients diagnosed by UBT had a higher risk of not undergoing a confirmatory test.ConclusionsInvestigation of H. pylori infection by gastroenterologists is rare in absence of a formal indication; however, endoscopy is commonly used for dyspeptic patients <55 years without red flags and non‐invasive tests are still used for dyspeptic patients ≥55 years or presenting alarm signs. Men, patients under 55 years, and patients diagnosed by UBT have an increased risk of being lost to follow‐up after eradication treatment.
UreBimmunodominant epitope‐specificCD8+T‐cell responses were beneficial in reducing gastric symptoms inHelicobacter pylori‐infected individuals
Authors: He Taojun , Zhang Fang , Zhang Jin , Wei Shanshan , Ning Jie , Yuan Hanmei , Li Bin 
Published: February 2023

AbstractBackground and aimsAlthoughHelicobacter pyloriis recognized as an extracellular infection bacterium, it can lead to an increase in the number of CD8+T cells after infection. At present, the characteristics ofH. pyloriantigen‐specific CD8+T cells and the epitope response have not been elucidated. This study was focused on putative protective antigen UreB to detect specific CD8+T‐cell responses in vitro and screen for predominant response epitopes.MethodsThe PBMCs collected fromH. pylori‐infected individuals were stimulated by UreB peptide pools in vitro to identify the immunodominant CD8+T‐cell epitopes. Furthermore, their HLA restriction characteristics were detected accordingly by NGS. Finally, the relationship between immunodominant responses and appearance of gastric symptoms afterH. pyloriinfection was conducted.ResultsUreB‐specific CD8+T‐cell responses were detected inH. pylori‐infected individuals. Three of UreB dominant epitopes (A‐2 (UreB443–451: GVKPNMIIK), B‐4 (UreB420–428: SEYVGSVEV), and C‐1 (UreB5–13: SRKEYVSMY)) were firstly identified and mainly presented by HLA‐A*1101, HLA‐B*4001 and HLA‐C*0702 alleles, respectively. C‐1 responses were mostly occurred inH. pylori‐infected subjects without gastric symptoms and may alleviate the degree of gastric inflammation.ConclusionsThe UreB dominant epitope‐specific CD8+T‐cell response was closely related to the gastric symptoms afterH. pyloriinfection, and the C‐1 (UreB5‐13) dominant peptides may be protective epitopes.
Evaluation of the effects of a proton pump inhibitor on Helicobacter pylori stool antigen testing
Authors: Kajihara Yusaku , Shimoyama Tadashi , Mizuki Ichiro 
Published: February 2023

AbstractBackgroundSome patients find it difficult to discontinue proton pump inhibitors (PPIs). Unlike the 13C‐urea breath test (UBT), the stool antigen test (SAT), particularly when domestically produced kits are used, may be less likely to yield false‐negative results.MethodsThis prospective study included a convenience series of 35 healthy Japanese subjects. Based on a statistical calculation, acceptable numbers of subjects were considered at least 21 and 11 with and without Helicobacter pylori (H. pylori) infection, respectively. The H. pylori infection was determined using the UBT or rapid urease test. SATs were performed with three novel domestically produced kits (the rapid immunochromatography tests Quick Navi™‐H. pylori [Navi™] and Quick Chaser® H. pylori [Chaser®], and the bioluminescent enzyme immunoassay test BLEIA® ‘EIKEN’ H. pylori Antigen [BLEIA®]) before and after oral PPI administration (30 mg lansoprazole once daily for 14 days). For each kit, the sensitivities and specificities were calculated and compared before and after PPI administration. Furthermore, the cutoff index (COI) values of BLEIA® before and after PPI administration were compared in H. pylori‐infected subjects.ResultsH. pylori infection was detected in 68.6% (24/35) of the included subjects. The sensitivities and specificities before versus after PPI administration were as follows: 79.2% (19/24) and 100.0% (11/11) versus 75.0% (18/24) and 100.0% (11/11) for Navi™, respectively (p = 1); 87.5% (21/24) and 100.0% (11/11) versus 75.0% (18/24) and 100.0% (11/11) for Chaser®, respectively (p = .371); 100.0% (24/24) and 100.0% (11/11) versus 95.8% (23/24) and 100.0% (11/11) for BLEIA®, respectively (p = 1). The median COI values of BLEIA® before and after PPI administration were 1389.0 and 3207.25, respectively (p = .0839).ConclusionsIn stool specimens, H. pylori antigenicity is maintained even during PPI use. SAT using a bioluminescent enzyme immunoassay is particularly recommended because of its extremely high sensitivity.
A “new” option in Helicobacter pylori eradication: High‐dose amoxicillin dual therapy outperforms bismuth quadruple therapy in a high dual resistance setting
Authors: Macedo Silva Vítor , Lima Capela Tiago , Freitas Marta , Boal Carvalho Pedro , Magalhães Joana , Cotter José 
Published: February 2023

AbstractBackgroundCurrently, bismuth quadruple therapy (BQT) is indicated as a first‐line treatment for Helicobacter pylori eradication in areas with high dual metronidazole and clarithromycin resistance, with its use being limited by its low tolerability and significant cost. A novel regimen with high‐dose amoxicillin dual therapy (HDADT) has emerged as an alternative. The aim of this study was to compare the results of these two treatments on HP eradication.Materials and MethodsProspective randomized study including 100 consecutive patients undergoing H. pylori eradication. Each patient was randomized (in a 1:1 ratio) to one group of treatment: BQT (bismuth 140 mg + metronidazole 125 mg + tetracycline 125 mg, four times a day, for 10 days) or HDADT (amoxicillin 1000 mg alternating with amoxicillin 500 mg, four times a day, for 14 days), both associated with esomeprazole 40 mg twice a day. The primary aim was to compare treatments' efficacies. Secondary aims were to assess symptoms persistence and tolerability.ResultsA total of 100 patients were included, 54% women, with a mean age of 55 ± 14 years. From these, five were lost to follow‐up. Effective eradication proven by negative stool antigen test was significantly higher in patients randomized to HDADT when compared to BQT for both intention‐to‐treat (ITT) (96.2% vs. 81.4%; p = .022) and per‐protocol (PP) (95.9% vs. 81%; p = .025) analysis. These differences were even more pronounced when only considering second line treatment (100% vs. 62.5%; p = .028). Side effects did not differ significantly between BQT and HDADT groups for both ITT (7.0% vs. 2.0%; p = .254) and PP (4.8% vs. 0%; p = .210) analysis.ConclusionsWhen compared to BQT, treatment with HDADT presented higher and near 100% efficacy in eradicating H. pylori, without differences in reported side effects or compliance. This treatment represents an important alternative for populations with increasing incidences of resistance to the currently recommended antibiotic regimens.
Solution combustion synthesis of FeCr2O4:Zn,Al pigment powders
Authors: Paborji Fatemeh , Shafiee Afarani Mahdi , Arabi Amir Masoud , Ghahari Mehdi 
Published: February 2023

AbstractFeCr2O4:Zn,Al pigment powders were prepared via a solution combustion synthesis method. Effects of Zn and Al dopants and less/extra Fe content on the structure, molecular bonds, and optical properties of powders were studied. Results showed that addition of dopants as well as extra/less content of Fe led to weaker combustion and consequently lower X‐ray diffraction peak intensities, lattice parameters, and differential thermal analysis peak intensities. Moreover, Fourier transform infrared analysis illustrated that the band position of Cr–O and Fe–O bonds were shifted to higher frequencies with moving away from stoichiometry. In addition, scanning electron micrographs showed that in all samples, porous spongy microstructures were formed with highly flake‐like agglomerated particles. Furthermore, there was a significant difference between the powder samples and the tiles colored with in glaze powders due to the partial dissolution of pigments in contact with the molten glaze of tiles. In comparison to the tile colored with the stoichiometric FeCr2O4 pigments without dopants, the color difference (ΔE) in the tiles colored by the iron chromite pigments doped with Zn and Al dopants and less/extra Fe content reached the high values as large as ΔE = 36.19. The solar reflectance values (Rs) in near‐infrared region were above 50% in all samples. Near 80% Rs in the tile colored by the iron chromite pigment doped with 3 mol% Zn and the yellowish brown appearance (L* = 43.44, a* = 6.77, b* = 18.38, c* = 19.59, h = 69.79) showed that the sample was a good candidate for cool building materials such as roof tiles.
Rapid detection of sea bass quality level with machine learning and electronic nose
Authors: Yavuzer Emre 
Published: February 2023

SummaryIn the present study, the odour changes of sea bass was measured and recorded with Arduino‐based six gas (MQ) sensors during 7 days of storage. In addition, the changes in biogenic amines (BAs) and total viable count (TVC) occurring in fish meat during storage were determined daily and compared with electronic nose data. For image processing, 500 fish data were taught to Teachable Machine (TM) daily, a web‐based machine learning platform. In the study, it was determined that if the level of putrescine (PUT) exceeds 1 mg kg−1 and spermidine (SPMD) exceeds the level of 2 mg kg−1, the MQ4, MQ5, MQ8 and MQ9 sensors exceed the value of 500. In the study, it was determined that combined machine learning and electronic nose could be used as a rapid quality determination tool in a perishable food such as fish.
Role of CD14 in human disease
Authors: Sharygin Daniel , Koniaris Leonidas G. , Wells Clark , Zimmers Teresa A. , Hamidi Tewfik 
Published: February 2023

AbstractThe cell surface antigen CD14 is primarily understood to act as a co‐receptor for toll‐like receptors (TLRs) to activate innate immunity responses to pathogens and tissue injury in macrophages and monocytes. However, roles for CD14 are increasingly being uncovered in disease responses in epithelial and endothelial cells. Consistent with these broader functions, CD14 expression is altered in a variety of non‐immune cell types in response to a several of disease states. Moreover, soluble CD14 activated by factors from both pathogens and tissue damage may initiate signalling in a variety of non‐immune cells. This review examined the current understanding CD14 in innate immunity as well as its potential functions in nonimmune cells and associated human diseases.
Effectiveness of a smartphone application on dental anxiety in adolescents: A randomized controlled trial
Authors: Mayer Trícia Murielly Andrade de Souza , Maior Giovanna Burgos Souto , da Costa Nataly Pereira , do Nascimento Michele Gomes , Colares Viviane 
Published: February 2023

AbstractBackgroundDental anxiety is a common issue among adolescents. Despite the use of smartphones being an important part of their daily lives, only a few digital‐based interventions for dental anxiety have been tested in randomized controlled trials (RCT).AimThe aim of this study was to evaluate a new smartphone application (App) named FALE, which was designed to demonstrate interest from the dentist to adolescent and to reduce dental anxiety.DesignThis is a RCT in which 184 adolescents aged 10–19 years were randomly allocated into the intervention group (IG) or the control group (CG). The intervention was applied in the waiting room before the consultation at a dental clinic. The IG answered the FALE, which contained 14 questions—of which the first and last questions addressed anxiety, whereas the CG answered the question about anxiety twice with an interval between them.ResultsThere was a significant difference in the distribution of anxiety rating frequencies before and after the intervention period in both groups. For the IG, there was a reduction in anxiety after the intervention of 16.29%, and, in the CG, a reduction of 2.2% (p < .001).ConclusionThe FALE App effectively reduced dental anxiety before the appointment.
On the confluence of ultrafast high‐temperature sintering and flash sintering phenomena
Authors: Raj Rishi , Wolf Dietrich E. , Yamada Carolina N. , Jha Shikhar K. , Lebrun Jean‐Marie 
Published: February 2023

AbstractUltrafast high‐temperature sintering (UHS) and flash sintering are novel methods for rapid sintering of ceramics, often completed in just a few seconds. Here, we show that both also share two additional features: an abrupt rise in electrical conductivity, which is electronic, and electroluminescence. More fundamentally, both are related to phonon physics where MD calculations have shown that proliferation of phonons at the edge of the Brillouin zone can induce Frenkel pairs without the application of electrical fields. Here, we show that, indeed, heating without the application of electric field, can also induce flash: Rapid heating processes of thin films of an oxide‐salt deposited on silk fibers, with a propane torch, are shown to induce electronic conductivity, electroluminescence, and rapid sintering of the oxide. The discussion in this article harkens back to two inventions, more than a century ago, which can now be related to flash and UHS: (i) the Nernst glow lamp circa 1900, made from zirconia, and (ii) the Welsbach mantle, constituted from ceria doped thorium oxide, in the late nineteenth century. Thus, the confluence between high heating rate and electric field induced flash phenomena links the past to the new. The emerging question is how injection of phonons that has been shown to create Frenkels can further induce high electronic conductivity and electroluminescence in oxides. Both electronic conductivity and luminescence are likely related to the generation of electron–hole pairs.
Prediction of ring crack initiation in ceramics and glasses using a stress–energy fracture criterion
Authors: Papšík Roman , Ševeček Oldřich , Martin Éric , Bermejo Raúl 
Published: February 2023

AbstractCrack initiation in brittle materials upon spherical indentation is associated with the tensile radial stresses during loading. However, location of crack onset often differs (offset) from the site of maximal stress. In addition, experiments reveal a strong dependency of crack initiation forces on geometrical parameters as well as the surface condition of the sample. In this work, a coupled stress–energy fracture criterion is introduced to describe the initiation of ring cracks in brittle materials, which takes into account the geometry of the contact and the inherent strength and fracture toughness of the material. Several experiments reported in literature are evaluated and compared. The criterion can explain the location offset of the ring crack upon loading, as observed in various ceramics and glasses. It also predicts the ring crack initiation force upon contact loading, provided that surface compressive stresses, introduced during grinding or polishing processes, are taken into account. Furthermore, the stress–energy criterion may be employed to estimate the surface residual stress of ceramic parts, based on simple contact damage experiments.
B4C–(Ti0.9Cr0.1)B2 composites with excellent specific hardness and enhanced toughness
Authors: Qiu Shuaihang , Zou Ji , Liu Jingjing , Zhou Yanchun , Ji Wei , Zhang Fan , Wang Weimin , Fu Zhengyi 
Published: February 2023

AbstractDense and light B4C–(Ti0.9Cr0.1)B2 composites with excellent mechanical properties were designed and reactively densified from boron, TiC, and Cr3C2 powder mixtures by spark plasma sintering in this work. Due to solid solution effects, the as‐obtained B4C–(Ti0.9Cr0.1)B2 composite exhibited obviously enhanced hardness (43.2 ± 3.0 GPa at 9.8 N) and higher specific hardness (12.82 GPa cm3 g−1) together with improved flexural strength (663 ± 39 MPa) and fracture toughness (KIC, 5.40 ± 0.25 MPa m1/2), compared to the counterparts such as B4C–TiB2 composite and B4C. Toughening contributions in the as‐sintered ceramics were quantitatively analyzed, and higher KIC in B4C–(Ti0.9Cr0.1)B2 was mainly due to their larger initial fracture toughness and compressive stress toughening. The combination of these properties makes B4C–(Ti0.9Cr0.1)B2 composites exhibit great potentials in the application as lightweight structural materials. This work provided an inspiration to achieve lightweight materials with high performance through doping minor‐amount atoms into the matrix.
Additive manufacturing of high mechanical strength continuous Cf/SiC composites using a 3D extrusion technique and polycarbosilane‐coated carbon fibers
Authors: Chen Ruoyu , Bratten Adam , Rittenhouse Joshua , Leu Ming , Wen Haiming 
Published: February 2023

AbstractA novel additive manufacturing approach is herein reported for manufacturing high mechanical strength continuous carbon fiber‐reinforced silicon carbide (Cf/SiC) composite materials. Continuous carbon fibers were coated with polycarbosilane (PCS) using a colloidal evaporative deposition process and then coextruded with high solid content SiC ink. The zeta potential of the SiC ink was adjusted to optimize the printing ability of the suspension. During sintering, small SiC grains and whiskers were generated in the gaps in and around the PCS‐coated carbon fibers, which led to the improved flexural strength and density of the composites. Meanwhile, the PCS coating on the surface of the carbon fibers prevented the carbon fibers from reacting with SiO gas generated by reactions between the SiC matrix and SiO2 and sintering additives (Al2O3 and Y2O3), effectively preserving the structural integrity of the carbon fibers. Compared to the SiC specimens containing uncoated carbon fibers, the density of the specimens fabricated with coated carbon fibers was increased from 2.51 to 2.85 g/cm3, and the strength was increased from 190 to 232 MPa.
Cracking mechanism in laser directed energy deposition of melt growth alumina/aluminum titanate ceramics
Authors: Huang Yunfei , Wu Dongjiang , Yu Xuexin , Ma Guangyi , Han Jun , Wang Hong , Niu Fangyong 
Published: February 2023

AbstractThanks to its advantages of high efficiency and near‐net shaping, laser directed energy deposition (LDED) is rapidly becoming a remarkable preparation technology for high‐purity ceramics. However, the cracking problem in shaping process is always a great challenge for LDED to achieve industrial application. For this purpose, alumina/aluminum titanate melt‐growth ceramics (A/AT MGCs) were prepared using LDED system, and the corresponding finite element thermal analysis model was developed. The solidification behavior and cracking mechanism of A/AT MGCs were investigated based on the thermal analysis model, and the influence of process parameters on the cracking characteristics was revealed with experiments. Results show that the crack morphology and distribution are controlled by microstructure and temperature gradient together. The scanning speed of 100–150 mm/min, with better microstructure and lower temperature gradient, is a preferred process window. This study provides theoretical guidance and technical support for the cracking suppression during LDED shaping of ceramics.