bluuebunny/crossref_metadata_2025_split huggingface dataset:
Student Academic Stress on E-Learning Systems
Authors: . Kamria , . Nurwati , Momo Halim , Maharani Sriwiyati 
Published: September 2023

The aim of this research is to analyze the about causes of academic stress, what types of the causes, and the impact of academic stress using the Perceived Stress Scale and the student academic stress on e-learning systems model. This project employs case study research methods. The results of the studies Based to the study academic stress can have a negative impact on students' physical and mental health. These effects include fatigue, poor concentration, or anxiety. There may cause students to lose confidence in themselves and have problems concentrating. Effects from overthinking on social interactions and learning attendance. Factors that cause academic stress of students participating in e-learning system were identified by several informants, who reported that learning motivation was lost during online learning. They cited various reasons such as laziness, boredom, inability to manage time, loss of concentration and lack of engagement with studies. Several whistleblowers admitted that the environment is not peaceful, which makes it difficult to study. Internet network is very important factor of online learning because without internet network online learning is not easy. From accessing materials, completing coursework, completing assignments, and submitting assignments, almost all online learning activities require Internet access. Based on the results of the data analysis of the Perceived Stress Scale level of academic stress of students SMA Negeri 1 Lasolo Konawe Utara during online learning is placed in the medium category.
In vitro antileishmanial evaluation of Vernonia Brachycalyx leaf latex extract against two leishmania species
Authors: Feroche Alemu Tadesse 
Published: September 2023

: Leishmaniasis is a major public health problem, and the alarming spread of parasite resistance has increased the importance of discovering new therapeutic products. In the present study, the antileishmanial activity of the methanolic extract of the leaf latex obtained from the Ethiopian plant Vernonia brachycalyx O. H. (family Asteraceae) was evaluated by in vitro testing against Leishmania aethiopica and . : Antileishmanial activity test was carried out using the Alamar Blue assay on promastigotes and axenic cultured amastigotes of and clinical isolates, and cell viability was fluorometrically determined. Amphotericin B was used as a positive control, and 1% dimethyl sulfoxide (DMSO) and the media were employed as a negative control.Moreover, preliminary phytochemical analysis of the extracts was performed.: Results of the study indicated that the latex possesses good activity against both parasites, with IC values of6.82 ± 0.18 and 6.34 ± 0.20μg/ml against promastigotes and 3.53 ± 0.33 and 2.61 ± 0.907μg/ml against axenically cultured amastigotes of and , respectively. The latex demonstrated selectivity indices (SIs) of 15.27 and 16.42 against promastigotes and 29.50 and 39.90 against axenically cultivated amastigotes of and . While, amphotericin B demonstrated SIs of 7.91 and 8.23 against promastigotes and 7.45 and 7.73 against axenically cultured amastigotes of and , respectively. Phytochemical screening demonstrated that the latex contains flavonoids, tannins, cardiac glycosides, terpenoids, saponins, alkaloids, and steroids. : The findings of this investigation attest that the latex of V. brachycalyx possesses promising antileishmanial activity against and , warranting further investigations into the active constituents.
Sol Vetrikül destek cihazı olan hastalarda sağ kalp yetmezliği ile sol vetrikül destek cihazı trombozu arasında ilişki var mıdır?
Authors: BEYAZPINAR Deniz Sarp , GÜNERTEM Eren , ERSOY Özgür , İNCE İlker 
Published: September 2023

Amaç: Sol ventrikül destek cihazı (LVAD) ileri dönem kalp yetmezliği tedavisinde kullanılan metodlardan biridir. Erken dönemde kalp nakline köprülemek amacı ile kullanılan sol ventrikül destek cihazları kalp nakli verici sayısının kısıtlı olması sebebi ile artık destinasyon tedavisi olarak kullanımı her geçen gün artmaktadır. LVAD ile geçirilen süre uzadıkça komplikasyonlarda artmaktadır. Bu komplikasyonlardan en mortal olanı LVAD trombozudur. Bu mortal komplikasyonun önlenebilmesi amacı ile risk faktörlerinin aydınlatılması çok önemlidir.
Gereç ve Yöntemler: Nisan 2012 ile ocak 2020 tarihleri arasında, toplam 80 LVAD hastası retrospektif olarak değerlendirilmiştir. Hastaların veri tabanından demografik özellikleri, yandaş hastalıkları, preoperatif tetkikleri, LVAD data kayıtları kayıt altına alınılmıştır. Sağ ventrikülün kasılma fonksiyonlarını değerlendirmek amacı ile ameliyat öncesi dönemde yapılmış olan ekokardiyogram tetkiklerinde triküspid kapak anüluler hareketinin ölçümü (TAPSE) değeri kullanılmıştır.
Bulgular: Çalışmaya toplam 60 hasta dahil edilmiştir. Bu hastalardan sağ ventrikül fonksiyonları, normal veya hafif etkilenmiş olan (TAPSE≥17) ve orta veya ileri etkilenmiş (TAPSE
The Effect of 12-Week Face-to-Face and Online HIFT Training on Certain Cardiovascular Biomarkers
Authors: ÇAKAR SAKA Serra Ayşe , ÇAMLIGÜNEY Filiz 
Published: September 2023

Aim: The aim of our study is to examine the effect of physical activity performed face-to-face and online for 12 weeks on body composition and blood values (HDL, LDL Triglyceride and Fasting Blood Glucose) in sedentary women.
Material and Methods: Inactive sedentary female participants aged 24-52 participated in the study on a voluntary basis within the framework of the Declaration of Helsinki. Participants were divided into two groups as face-to-face (n= 21) and online (n=19). Participants were given functional training with 60% loading for the first 6 weeks and then 80% loading with the HIFT training method 3 days a week for 12 weeks. Bioelectrical impedance and blood tests (HDL, LDL, Triglyceride, Fasting Glucose) were taken from all participants prior to the training program and after 12 weeks of training. The data were analyzed in SPSS 22.0 program. Shapiro-Wilk test was used for normality test. Wilcoxon Signed Rank Test was used for intragroup comparisons and Mann Whitney-U test was used for intergroup comparisons. For statistical significance, p
Analysis of risk factors for postoperative complications in assessing the results of surgical treatment of patients with perforated ulcer
Authors: Magomedov M. М. , Omarov M. D. , Magomedov M. A. 
Published: September 2023

Emergency operations for perforated gastroduodenal ulcers are associated with a high incidence of postoperative complications. A number of studies have examined the impact of perioperative risk factors and comorbidities on postoperative morbidity after abdominal surgery, but only a few have looked at their role in perforated peptic ulcer disease.Aim. To determine possible associations between postoperative complications, comorbidity and perioperative risk factors for perforated gastroduodenal ulcer.Materials and methods. This study includes the anamnesis of 142 patients who underwent surgery for perforated gastroduodenal ulcer (PGD). In 74 cases (52.1 %), minimally invasive suturing operations were performed, in 68 cases, laparotomy suturing (47.9 %), in three cases, gastric resection was performed (2.3 %). Comparative studies between groups have not been conducted. Clinical data regarding patient characteristics, surgical techniques, and complications were collected retrospectively.Results. Postoperative complications associated with operations for perforated gastroduodenal ulcers amounted to 26.8 %, or 38 cases. A univariate analysis showed that prolonged open surgical time in female patients≥60 years of age, as well as a high American Society of Anesthesiologists (ASA) score, and the presence of preoperative shock were significant perioperative risk factors for postoperative complications. Significant comorbid risk factors included hypertension, diabetes mellitus, and lung disease. Multivariate analysis showed that long operation times, open surgery, high ASA scores, and preoperative shock were independent risk factors for postoperative complications in perforated gastroduodenal ulcer.Conclusions. High ASA, preoperative shock, open surgery, and long operative times of more than 148 minutes are high risk factors for morbidity. However, there is no association between postoperative complications and comorbidity in patients with perforated ulcers.
Marital status of a patient in the formation of his attitude to the organization of medical care provided on an outpatient basis
Authors: Cherkasov S. N. , Martirosov A. V. , Fedyaeva A. V. , Kudryashova L. V. 
Published: September 2023

Introduction. The marital status of the patient is an important factor that affects his behavior, attitude to health and the healthcare system. Family relationships can have a positive or negative impact on the level of self-esteem, general psychological stability and readiness for treatment. For example, many people in stable relationships are more likely to monitor their health, visit doctors regularly and receive the necessary medical care. However, there are also negative aspects of marital status that can affect the patient's attitude to the healthcare system. For example, some patients may experience fear and embarrassment when seeking medical care without their spouse or partner. There are also cases when a patient's unwillingness to go to doctors is due to the fact that he does not want financial or emotional help from his family, but prefers to cope with his problems on his own. Thus, marital status is an important factor that must be taken into account when analyzing the attitude of patients to the healthcare system. Studying this problem can help medical institutions develop more effective service strategies and increase patient satisfaction.Materials and methods. For the analysis, 495 patients of medical organizations in Moscow were obtained by questioning. Two comparison groups were formed, the main group (the presence of marital relations) 292 people, the control group (the absence of marital relations) 203 people. Taking into account the nonparametric distribution of the primary data, the criterion of the reliability of differences χ2 was used to compare the groups, and the association coefficient was used to determine the dependence Ka.Results. According to the results of the analysis, taking into account the literature data, data on different approaches to the assessment of the medical care management system in patients with different family status were obtained.Conclusions. Family patients are more critical of the organization of the activities of individual departments of the polyclinic, but their criticism does not lead to a significant decrease in the overall assessment of the medical organization. Lonely patients make fewer specific claims, but reduce the overall assessment of the medical organization's activities.
Does delaying surgery following induction chemotherapy compromise survival in patients with mesothelioma?
Authors: Wong Lye-Yeng , Baiu Ioana , Leipzig Matthew , Titan Ashley , Liou Douglas Z. , Lui Natalie , Berry Mark , Shrager Joseph B. , Backhus Leah 
Published: September 2023

Objective: The ideal time interval between induction chemotherapy and surgery and the impact on cancer mortality in patients with mesothelioma remains unclear.
Methods: We queried the National Cancer Database (2004-2017) for patients with favorable prognostic factors considered for surgery. Immediate surgery was performed within 3 months following the start of induction chemotherapy, while delayed surgery was defined as surgery performed later than 3 months. We compared both groups to those who did not have an operation despite being surgical candidates, as well as to those who were treated with surgery only. Overall mortality was assessed using Cox proportional hazard models adjusting for covariates.
Results: A total of 4,294 patients were included, with the majority of patients undergoing induction chemotherapy followed by no surgery (3,370, 78%). The proportion of patients undergoing both immediate and delayed surgery increased over the last decade, but delayed surgery continued to be more common. There were no significant differences in baseline characteristics between the immediate and delayed surgery groups. Higher comorbidity scores were significantly associated with an increased risk of death on multivariable analysis, but the timing of surgery was not. This held true with a sensitivity analysis using 6 months as the definition of delayed surgery.
Conclusions: This study shows that delaying surgery following induction chemotherapy does not compromise overall survival in patients with mesothelioma.
Solutions on the Existence of a Novel Type of Hemivariational Inequality Systems
Authors: Azeez Ali Dhurgham , Hashoosh Ayed E. 
Published: September 2023

Abstract
This paper aims to show that there are solutions to a novel class of hemivariational inequality (H.VI) whose results are described in a set of a reflexive Banach space X_n. In the first section, we discuss the link between our inequality issues and equilibrium issues. The second uses some nonlinearity (H.VI) results for their extension.
The Postponed Regional Head Elections in Emergency Situations: a Constitutional Democracy Perspective in Indonesia
Authors: Ahsan Fikri , Andrianto Wahyu , Achmad Andaru Djarot Dimas , Hanapi Mohamad Mohamad 
Published: September 2023

<p>The postponement of regional head elections may be done when the country is declared in a state of emergency. Emergencies such as war, economic crises, disease epidemics, and natural disasters affect the constitutional rights of citizens regulated by the 1945 Constitution. Therefore, legal instruments are needed to avoid unconstitutionality in fulfilling constitutional rights and democratic values during emergencies or dangers, including postponing regional elections during the COVID-19 pandemic. Article 12 of the 1945 Constitution is the most relevant legal basis for activating emergency constitutional law when the state is declared dangerous. However, Article 22 of the 1945 Constitution was preferred in postponing regional elections. Even though the holding of elections itself is guaranteed by the constitution every five years, on the other hand, the constitution has not regulated the postponement of elections if the country is in danger or an emergency. So, in the future, there will need to be constitutional amendments and new regulations that further widen the spectrum of dangerous or emergency conditions without forgetting Article 12 of the 1945 Constitution as a consideration</p>
Magmatic Native Gold: Composition, Texture, Genesis, and Evolution in the Earth’s Crust
Authors: Berdnikov N.V. , Kepezhinskas P.K. , Nevstruyev V.G. , Krutikova V.O. , Konovalova N.S. 
Published: September 2023

Abstract
—Here we report results of microforms’ studies of native gold and its alloys in igneous rocks, modified to varying degrees by secondary processes. We discuss the composition and occurrence of both the deep-seated magmatic gold-bearing alloys and the products of their transformation under conditions of the upper Earth’s crust. Gold-bearing Kamchatka adakites and ankaramites, Ildeus massif mafic-ultramafic intrusions and adakites from the Stanovoy fold system as well as dacites from the Bolivian Andes were formed during melting of either the suprasubduction mantle wedge or the subducted oceanic crust. In depleted peridotites from the Avachinsky Volcano in Kamchatka as well as suprasubduction ophiolites from Polar Urals, Eastern Sayan and the Western Mediterranean Betic–Rifean belt, the gold-bearing mantle was hybridized by subduction-related melts and high-temperature fluids. Volcanic rocks associated with the Lesser Khingan Fe–Mn deposits and Zolotaya Gora Au deposit in Southern Urals as well as Taragai ultramafic rocks in the South Khingan Range display subduction-related geochemical characteristics. Gold-bearing trachytes in the Virginian Appalachians (USA) represent felsic differentiates of mafic intraplate magmas. We propose that one of the principal forms of gold transport into the upper crustal environments is represented by Cu–Ag–Au alloys, which precipitated from mantle-derived silicate melt enriched in chalcophile and siderophile elements. Such Cu–Ag–Au alloy-rich magmatic rocks can either constitute primary sources of precious metals in the mantle-crust system or serve as geochemical precursors to the formation of native gold assemblages in epithermal and mesothermal ore deposits. Presence of magmatic gold particles in subduction-related igneous rocks and mantle restites hybridized by subduction-derived melts and high-temperature fluids suggest the existence of gold-rich horizons in the Earth’s mantle at depths comparable to typical depths of generation of primary convergent zone and some within-plate magmas.
Externalities of the sanction pressure policy and its consequences for the Russian small and medium business development
Authors: Koroleva E. A. 
Published: September 2023

Objective: to analyze the impact of the externalities of the sanctions pressure policy on small and medium-sized enterprises and to develop specific proposals that allow them to adapt to the conditions of uncertainty.Methods: general scientific methods of systemic, structural and comparative analysis, as well as specific scientific methods (static and graphical analysis, expert assessments).Results: the analysis was carried out of the externalities of the sanctions pressure policy, which significantly affected the activities of the Russian small and medium-sized enterprises. Among the key factors studied are the disruption of logistics chains, reduction of the customer base, restrictions on monetary transactions, blocking of digital platforms, etc. The special role of this sector in eliminating the imbalances of the country’s economy in a difficult geopolitical situation and economic instability is outlined. It is proposed to investigate ways of adapting small businesses to new economic conditions, taking into account the systematic classification of enterprises in the SME sector. The forecast trends in the development of small and medium-sized firms for the near future are formulated. Based on the analysis of externalities, the author suggests measures to increase the adaptability of enterprises in the studied segment of the economy, which can be used by both representatives of the business community and government agencies.Scientific novelty: the division of firms into three categories (“kids”, “genetic dwarfs”, “transformers”) and three subgroups (“travelers”, “reorganizers”, “imago”) is proposed; their key functions and ways of adaptation characteristic of each category of enterprises are identified, which made it possible to develop recommendations on improving the adaptability of small and medium-sized enterprises, taking into account their characteristics.Practical significance: the main provisions and conclusions of the article can be used in the educational process of educational institutions; in scientifi activities for the development of academic competencies on the functioning of small and medium-sized enterprises; in the work of organizations that make up the infrastructure for the development and support of SMEs; they also contribute to the study of ways and strategies for the entrepreneurship adaptation under exogenous shocks.
A surprising excess of radio emission in extremely stable quasars: a unique clue to jet launching?
Authors: CAI Zhen-Yi , Kang Wen-Yong , Wang Junxian , Wang Haochen , Ren Wen-Ke , Liao Mai , Yuan Feng , Zdziarski Andrzej 
Published: September 2023

Abstract
Quasars are generally divided into jetted radio-loud (RL) and non-jetted radio-quiet (RQ) ones, but why only roughly 10% quasars are radio loud has been puzzling for many decades. Other than jet-induced-phenomena, black hole mass, or Eddington ratio, prominent difference between jetted and non-jetted quasars has scarcely been detected. Here we show that a unique distinction between them and the mystery of jet launching could be disclosed by a surprising excess of radio emission in extremely stable quasars (ESQs, i.e., type 1 quasars with extremely weak variability in UV/optical over 10 years). Specifically, we find that >25% of the ESQs are detected by FIRST/VLASS radio survey, while only ~ 6-8% of its control sample, matched in redshift, luminosity, and Eddington ratio, are radio detected. The excess of radio detection of ESQs has a significance of 4.4σ (99.9995%), and dominantly occurs at intermediate radio loudness with ~ 10 -- 60. The radio detection fraction of ESQs also tends to increase in the ESQ samples selected with more stringent thresholds. Our results reverse the common view that RL quasars are likely more variable in UV/optical due to jet contamination. New clue/challenge posed by our findings imminently demands extensive follow-up observations to probe the nature of jets in ESQs, and theoretical studies on the link between jet launching and ESQs. Moreover, the discovery makes ESQs, a population which has never been explored, unique targets in the blooming era of time domain astronomy, like their opposite counterparts of quasars exhibiting extreme variability or changing-look feature.
Dissection of salt tolerance in cotton germplasm by analyzing agro-physiological traits and ERF genes expression
Authors: Zafar Muhammad Mubashar , Chattha Waqas Shafqat , Ali Arfan , Parvaiz Aqsa , Amin Javaria , Shakeel Amir , Saleem Huma , Shoukat Abbas , Ercisli Sezai , Razzaq Abdul , Qiao Fei 
Published: September 2023

Abstract
The development of genotypes that can tolerate high levels of salt is crucial for the efficient use of salt-affected land and for enhancing crop productivity worldwide. Therefore, incorporating salinity tolerance is a critical trait that crops must possess. Salt resistance is a complex character, controlled by multiple genes both physiologically and genetically. To examine the genetic foundation of salt tolerance, we assessed 16 F1 hybrids and their eight parental lines under normal and salt stress (15 dS m− 1) conditions. Under salt stress conditions significant reduction was observed for plant height (PH), bolls/plant (NBP), boll weight (BW), seed cotton yield (SCY), lint% (LP), fiber length (FL), fiber strength (FS), potassium to sodium ratio (K+/Na+), potassium contents (K+), total soluble proteins (TSP), carotenoids (Car) and chlorophyll contents. Furthermore, the mean values for hydrogen peroxide (H2O2), sodium contents (Na+), catalase (CAT), superoxidase (SOD), peroxidase (POD), and fiber fineness (FF) were increased under salt stress. Moderate to high heritability and genetic advance was observed for NBP, BW, LP, SCY, K+/Na+, SOD, CAT, POD, Car, TSP, FL, and FS. Mean performance, and multivariate analysis of 24 cotton genotypes based on various agro-physiological and biochemical parameters suggested that the genotypes FBS-Falcon, Barani-333, JSQ-White Hold, Ghauri, along with crosses FBS- FALCON × JSQ- White Hold, FBG-222 × FBG-333, FBG-222 × Barani-222, and Barani-333 × FBG-333 achieved the maximum values for K+/Na+, K+, TSP, POD, Chlb, CAT, Car, LP, FS, FL, PH, NBP, BW, and SCY under salt stress and declared as salt resistant genotypes. The above-mentioned genotypes also showed relatively higher expression levels of Ghi-ERF-2D.6 and Ghi-ERF-7A.6 at 15 dSm− 1 and proved the role of these ERF genes in salt tolerance in cotton. The findings suggest that these genotypes have the potential for the development of salt-tolerant cotton varieties with desirable fiber quality traits.