bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes with Finerenone in Participants with Stage 4 CKD and Type 2 Diabetes
Authors: Sarafidis Pantelis , Agarwal Rajiv , Pitt Bertram , Wanner Christoph , Filippatos Gerasimos , Boletis John , Tuttle Katherine R. , Ruilope Luis M. , Rossing Peter , Toto Robert , Anker Stefan D. , Liu Zhi-Hong , Joseph Amer , Ahlers Christiane , Brinker Meike , Lawatscheck Robert , Bakris George ,   on behalf of the FIDELIO-DKD and FIGARO-DKD Investigators
Published: March 2023

Background
Patients with stage 4 CKD and type 2 diabetes have limited treatment options to reduce their persistent cardiovascular and kidney risk. In Finerenone in Chronic Kidney Disease and Type 2 Diabetes (FIDELITY), a prespecified pooled analysis of Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease (FIDELIO-DKD) and Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD), finerenone improved heart-kidney outcomes in participants with CKD and type 2 diabetes.

Methods
This FIDELITY subgroup analysis investigated the effects of finerenone in participants with stage 4 CKD (eGFR <30 ml/min per 1.73 m2). Efficacy outcomes included a cardiovascular composite (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure) and a kidney composite (kidney failure, sustained ≥57% decrease in eGFR from baseline, or kidney disease death).

Results
Of 13,023 participants, 890 (7%) had stage 4 CKD. The hazard ratio for risk of cardiovascular composite outcome with finerenone versus placebo was 0.78 (95% confidence interval, 0.57 to 1.07). The kidney composite outcome proportional hazards assumption was not met for the overall study period, with a protective effect only shown up to 2 years, after which the direction of association was inconsistent, and an observed loss of precision over time incurred on finerenone versus placebo risk differences. Nonetheless, albuminuria and rate of eGFR decline were consistently reduced with finerenone versus placebo. Adverse events were balanced between treatment arms. Hyperkalemia was the most common adverse event reported (stage 4 CKD: 26% and 13% for finerenone versus placebo, respectively); however, the incidence of hyperkalemia leading to permanent discontinuation was low (stage 4 CKD: 3% and 2% for finerenone versus placebo, respectively).

Conclusions
The cardiovascular benefits and safety profile of finerenone in participants with stage 4 CKD were consistent with the overall FIDELITY population; this was also the case for albuminuria and the rate of eGFR decline. The effects on the composite kidney outcome were not consistent over time.
VILLAGE FUND ACCOUNTING: ACCOUNTABILITY BASED SIRI’ NA PACCE IN REALIZING SUSTAINABLE VILLAGE DEVELOPMENT
Authors: Manrimawagau Bayan Andi Yustika , Haliah  , Kusumawati Andi 
Published: March 2023

Abstrac, Demands for accountability not only on central and local governments, but village governments also have same obligation in realizing accountable government. This study aims to see the accountability of village fund financial management in terms of siri'na pacce culture for sustainable village development. This research is a literature review, descriptive analysis. The result of this study is the implementation of village finances must be carried out effectively and efficiently, transparently and responsibly. To carry out this responsibility, agent directs all his abilities and expertise while sticking to cultural values of his region to produce quality financial information reports that can be trusted by the community. The contribution of cultural values in sustainable village development is the value of lempu' and ada' tongeng. The value of lempu' becomes a dimension of empowerment in the perception of responsibility which has a very meaning in relation to honesty. Ada' tongeng is seen as necessary as a code of conduct for the government to serve to maintain truth, validity and reliability in carrying out things.
Abstrak, Dewasa ini tuntutan akuntabilitas tidak hanya pada pemerintah pusat maupun daerah saja, tetapi pemerintah desa juga memiliki kewajiban yang sama dalam mewujudkan pemerintahan yang akuntabel. Penelitian ini bertujuan melihat akuntabilitas pengelolaan keuangan dana desa dari sisi budaya siri’na pacce untuk pembangunan desa yang berkelanjutan. Penelitian ini merupakan literature review, bersifat analisis deskriptif. Hasil penelitian ini yaitu penyelenggaraan keuangan desa harus dilaksanakan secara efektif dan efisien, transparan dan bertanggung-jawab. Untuk melaksanakan tanggungjawab tersebut maka agen mengarahkan semua kemampuan dan keahliannya dengan tetap berpegang teguh pada nilai-nilai budaya daerahnya untuk menghasilkan laporan informasi keuangan yang berkualitas dan dapat dipercaya oleh masyarakat. Kontribusi nilai budaya dalam pembangunan desa yang berkelanjutan yakni nilai lempu’ dan ada’ tongeng. Nilai lempu’ menjadi dimensi pemberdayaan dalam persepsi tanggung jawab yang memiliki makna sangat dalam kaitannya dengan kejujuran. Ada’ tongeng dipandang perlu sebagai kode perilaku bagi pemerintah berfungsi untuk menjaga kebenaran, kevalidan dan keandalan dalam melaksanakan sesuatu.
Root Dilaceration: A Case Report and Literature Review
Authors: Jin Carrol , Skilbeck Michael , Low Ana , Lin Wei , Au Carmen , Mei Li 
Published: March 2023

Abstract
The clinical management of impacted incisors affected by root dilaceration is challenging. This case report presents the treatment of an adolescent female patient who presented with a deeply impacted, rotated and dilacerated maxillary central incisor and also reviews the current literature on the definition, prevalence, aetiology, diagnosis, and treatment of the anomaly. The impacted and dilacerated incisor was successfully orthodontically treated following a two-stage surgical exposure and after being rotated 100 degrees in the sagittal plane (due to the deep impaction and severe displacement). A Ballista spring and piggyback appliance technique were used to elevate the tooth. The dilacerated incisor was successfully preserved and relocated in the dental arch. The pre-operative and post-operative CBCT scans showed no significant root resorption of the repositioned tooth.
COMMITMENT Of One Of The DOCTRINES SHAYKH AHMED IBN Al-SAYYID MUHAMMAD IBN Al-S SAYYID YASSIN SON Of SHEIKH ABDUL GHANI Al - HUSSEINI Al - SHAFIE(1224 H)
Authors: Ali Bilal 
Published: March 2023

This is a short message in the fundamentals of jurisprudence on the doctrine of Imam Shafi'i (may Allah have mercy on him) to Sheikh Ahmad Ibn al-Sayyid Muhammad Ibn al-Sayyid Yassin al-Habrawi, nicknamed the second Shafi'i, from the people of Aleppo Al-Shahba, the work of God's mercy in this letter of the important doors in the fundamentals of jurisprudence; And the second is the general obligation of a specific religion. It is not secret to the scholars of the importance of these two issues in the chapter of fatwa. This is the intention of the matter, relying on Allah Almighty To achieve this message, as for the board of the manuscript has dominated the work P (may God have mercy on him) highlights the tradition of the general to strive in the matter of what is his reference to the other Mufti? , And the disagreement in that detailed, and then the second question and the views of scientists in the commitment of a certain doctrine between the transferees and the abstainers and the conditions of this detailed, in addition to the issue of (tracking licenses).
In conclusion we ask conciliation and repayment, God arrived on our master Muhammad and his family and companions.
Proof of Applicatio and its Nodal Applications
Authors: Ahmed Othman 
Published: March 2023

ABSTRACT

This research labeled (the proof of application and its nodal applications) is considered one of the researches that dealt with one of the important proofs of speech scholars, which are used in response to some philosophers' concepts in the occurrence of the world, the negation of the absent, and the infinite dimensions. This research deals with the linguistic definition of the proof and the meaning of Application, it deals dealt with the idiomatic aspect of this proof, the types of proofs used by scholars of speech in establishing Islamic beliefs, and then it touches upon some important issues, such as: the occurrence of the world, the negation of the non-existent, and the diminishing of the dimensions.The research is ended with the most important resuits.
A Fundamental Study in the Almighty’s Saying: Take Pardon, Enjoin Custom and Reject the Ignorant
Authors: Marai Muhammad 
Published: March 2023

ABSTRACT

This paper is marked with (The Almighty’s saying: Take pardon and enjoin custom and view the polytheists - a fundamentalist study-) in which I dealt with the reason behind the revelation of the verse, with an explanation of the abrogator and the abrogated, the vocabulary of the verse, the general expressions contained in the verse, the meaning of the command contained in it, and the synonyms, With the statement of the speech addressed to the Prophet, the authoritative custom, the diligence of the Prophet, and praise be to God, Lord of the worlds, and may God bless our master Muhammad and his family and companions as a whole.
The Journey of the Prophet Musa, peace be Upon him, with the Righteous Worshipper - an Intentional Study
Authors: Abdel-Jabbar Mahmoud 
Published: March 2023

ABSTRACT

Surat Al-Kahf is one of the surahs of the Qur’an, which contains great stories and contains wisdom, sermons, and lessons. This surah has served by scholars and students of knowledge from various backgrounds, because it is abundant in arts. So I wanted to shed light on an aspect of these stories in order to address it both in terms of intentions and skills, so I chose the journey of our master Musa, peace be upon him for the most prominent aspect of the intentions in the story and its three events represented in the breach of the ship, the killing of the boy, the building of the wall, and how the righteous worshipper balanced between the evils that occurred to choose the lightest of them to commit in order to avoid the greater evil.
The Impact of Electronic Sales Contracts, the Vision Option as A Model
Authors: Mohamed Asaad 
Published: March 2023

ABSTRACT

The vision option is one of the selling options, and it is a contract between the seller and the buyer, according to which the buyer has the right to rescind the contract upon seeing the contracted party in the absence of what was stated in the contract signed, such as a change in a specific quality or thing in the contract.
With the presence of these new technologies and their working mechanisms, many problems have been found in electronic sales operations, which puts the buyer or customer in a situation of financial loss or the disadvantaged side because he does not know the existence of an option such as the option of vision, or the absence of the option of vision in the sales contract.
Also, the significance of the research is to invite the Iraqi legislator to find means or legislate laws that guarantee the customer’s right to such cases and keep pace with the development of the movement of electronic contracts, and the call to educate the general public about the need to take the right to the choice of vision when receiving the product or the goods.
The Famous Hadith of Umm Ma`bad (May Allah be Pleased with her) “Analytical Study”
Authors: Taher Hanaa 
Published: March 2023

ABSTRACT

The hadith of Umm Maabad (may Allah be pleased with her) is well-known in the books of the Biography of the Prophet. She described the Holy Prophet, when He passed by her to ask for some water and milk, such a unique description that many human beings cannot express. She described what she had felt and how she had noticed the perfection of His beauty, His appearance and the joy of His visage .
The blessing, grace, goodness, and benevolence came to Umm Maabad and her husband when the Prophet (peace be upon Him) came to them, after they were in distress, and famine nearly dying. In this story, there are many miracles, the most prominent of which is the milking of a completely exhausted and skinny sheep, and turning milk from it, which made Abu Maabad when seeing this miracle, declaring his conversion to Islam, and followed the Prophet to Madina El Monawara with his wife Umm Maabad (may Allah be pleased with them).
Umm Maabad(may Allah be pleased with her) had lived after the death of the Prophet of Allah - to the succession of Othman bin Affan (may Allah be pleased with him), and the companions appreciated her and knew her merits, may Allah Almighty be pleased with the companions of the Prophet of Allah.
In my research, followed the analytical method of this famous Hadith. I have studied this Hadith in an analytical study by documenting the Hadith, explaining the unfamiliars, verifying the narrators of the Hadith, explaining the opinions of the Validating scholars, and then explaining the Hadith. May Allah grant success.
Practical Prototypes of the Signs of Graphic Miracles in the Qur’anic ‘Ghareeb’ strange by Using Metaphor
Authors: Mohammed Omer , Hassan Ahmed 
Published: March 2023

The Holy Qur’an is the most honorable book, and the sciences related to it are also the most honorable sciences. As the research on the words of the Qur’an is in terms of the miraculous eloquence that represents the great miracle of the Prophet, the research in the rhetorical miracle is one of the most honorable sciences. When the miraculous eloquence is combined with the Qur’anic strangeness, it gives us another important angle that one can look through it at the miracle of the Qur’an and its greatness. This research mixed the miraculous eloquence with the knowledge of the strangeness of the Qur’an, and in discussing the miraculous eloquence through the Qur’anic strangeness from an important chapter of rhetoric, which is metaphor. It presents a view in which it shows the greatness of God’s words, and brings us closer to contemplating the verses of the Noble Qur’an. This title combines three sciences: the miraculous eloquence, the Qur’anic strangeness, and rhetoric, and the research was in the signs so that we would be searching for the signs. In the current paper it is not pretended to stand on the specifics of the miraculous, and the researcher has explained in the first section of this research the definition of metaphor and its divisions and other demands I dealt with applied models of the miraculous eloquence in the vocabulary of the Qur’anic strangeness through the metaphor and the researcher discussed in every model the strangeness of the word as being a metaphor. I have speculated on what God has made easy for me of graphic signs, using interpretations and sources that were interested in explaining rhetorical jokes and miraculous signs, and then I explain the hidden meanings and rhetorical signs that have been revealed to me through extensive research in the Qur’anic word.
Virtual neurosurgery anatomy laboratory: A collaborative and remote education experience in the metaverse
Authors: Gonzalez-Romo Nicolas I. , Mignucci-Jiménez Giancarlo , Hanalioglu Sahin , Gurses Muhammet Enes , Bahadir Siyar , Xu Yuan , Koskay Grant , Lawton Michael T. , Preul Mark C. 
Published: March 2023

Background:
Advances in computer sciences, including novel 3-dimensional rendering techniques, have enabled the creation of cloud-based virtual reality (VR) interfaces, making real-time peer-to-peer interaction possible even from remote locations. This study addresses the potential use of this technology for microsurgery anatomy education.

Methods:
Digital specimens were created using multiple photogrammetry techniques and imported into a virtual simulated neuroanatomy dissection laboratory. A VR educational program using a multiuser virtual anatomy laboratory experience was developed. Internal validation was performed by five multinational neurosurgery visiting scholars testing and assessing the digital VR models. For external validation, 20 neurosurgery residents tested and assessed the same models and virtual space.

Results:
Each participant responded to 14 statements assessing the virtual models, categorized under realism (n = 3), usefulness (n = 2), practicality (n = 3), enjoyment (n = 3), and recommendation (n = 3). Most responses expressed agreement or strong agreement with the assessment statements (internal validation, 94% [66/70] total responses; external validation, 91.4% [256/280] total responses). Notably, most participants strongly agreed that this system should be part of neurosurgery residency training and that virtual cadaver courses through this platform could be effective for education.

Conclusion:
Cloud-based VR interfaces are a novel resource for neurosurgery education. Interactive and remote collaboration between instructors and trainees is possible in virtual environments using volumetric models created with photogrammetry. We believe that this technology could be part of a hybrid anatomy curriculum for neurosurgery education. More studies are needed to assess the educational value of this type of innovative educational resource.
Knowledge transfer in educational institutions in light of social epistemology
Authors: Riziq Luthfi Baihaqi , Vazrin Rizqi , Prayitno Aryasatya Rafa 
Published: March 2023

<p class="MsoNormal" style="text-indent:0in;border:none;mso-padding-alt:31.0pt 31.0pt 31.0pt 31.0pt;
mso-border-shadow:yes">The field of social epistemology has been producing new
discourses about knowledge generation and transfer while not forgetting the
social aspects of them. One of its contributions is the acknowledgment of
epistemic agents other than some lone subject in transferring and generating
knowledge. For many centuries, people have been receiving knowledge through
educational institutions. Social epistemology now allows us to reexamine the
epistemology of education, primarily since education is usually made up of
testimonial knowledge<span style="color: rgb(74, 74, 74); background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">—</span>knowledge that is “transferred” by teachers to students simply
by the account of the teacher’s position as the educator. Philosophy of
education, up until recently, has been concerned with types of education
ideally pursued by students. However, social epistemology has turned our
attention to aspects beyond normativity and set about the questioning of the
nature of knowledge in education in the first place. We will see how, using
social epistemology as a framework, new approaches to inquire about education
and the transfer of knowledge can be determined. This paper will examine the
changes in which we understand knowledge transfer done by educational
institutions, particularly schools, considering the advances made in the field
of social epistemology. The hopes of the exploration carried out in this paper
are to reassess the way we go about the philosophy of education and to ignite
further discussions concerning social epistemology and its impact on education.<o:p></o:p></p>
Analysis of Bit Rate and Distance Variation on Multiplexing System of Indoor Li-Fi Technology Using Movable LED Panel
Authors: Fauza Khair  , I Wayan Mustika  , Anggun Fitrian Isnawati3  , Nur Azizah  
Published: March 2023

The major problem of using light fidelity (Li-Fi) technology is still limited to the line of sight (LOS) conditions, which poses a challenge to perform bandwidth efficiency to support increased bit rates, especially for indoor use. In addition, the distance between the lamp driver (transmitter) and the receiver becomes a critical discussion to determine the characteristics of propagation losses. Therefore, this study focuses on analyzing the performance of an indoor Li-Fi multiplexing system using a movable LED panel (LP) based on parameters of bit rate and distance variation on multiple-input multiple-output (MIMO) 2x2 and 4x4. The parameter analysis of signal quality included optical and electrical signal spectrum characteristics, signal-to-noise ratio (SNR), bit error rate (BER), and Q-factor parameters. Based on the results, the increase in bit rate and distance significantly increases the BER value and decreases the Q-factor value. Both the 2x2 and 4x4 mux systems can meet standards up to a bit rate of 30 Mbps at a LOS distance of 3 meters, while at a bit rate of 40 Mbps, there are no channels that meet the ITU-T standard. In addition, the quality of the signal received at a distance of 4 meters, the 2x2 mux system can only reach the standard at a bit rate of 20 Mbps for all channels. However, channel 3 and channel 4 on the 4x4 mux system model still have the BER and Q-factor values that meet the standard in the bit rate of 30 Mbps. However, the decrease in the SNR value affected by the bit rate increase and distance is insignificant. Therefore, it becomes an opportunity for further observation of the proposed multiplexing system, detection scheme, or responsivity, and signal processing on the receiver side to be reliable on the higher bit rate.