bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temperature dependent volumetric, viscometric and conductance studies of barium chloride in aqueous solution of citric acid: an insight into molecular interactions
Authors: Kumar Manish , Kant Shashi , Kaushal Deepika , Thakur Abhishek , Jaswal Vivek Sheel , Singh Dharmvir , Kumar Sunil , Chauhan Vinay 
Published: May 2023

Abstract
Alkaline earth metal salts and citric acid both play a vital role in our daily life in terms of biological importance, so in this regard, in the present study, we calculated density, speed of sound, conductance and viscosity of barium chloride (BaCl2) in concentration range (0.01–0.12 mol kg−1) in a binary solution of 0.01 mol kg−1 citric acid in water (CA + H2O) at temperatures between 303.15 and 318.15 K with gap of 5 K. The various parameters like apparent molar volume ϕ

v
, limiting apparent molar volume ϕ

v

o
, transfer volume Δ
tr

ϕ

v

o
, and partial molar volume expansibilities

Φ
E
o

${{\Phi }}_{E}^{o}$

were calculated using density data. Viscosity data has been applied to calculate relative viscosity and Jones Dole coefficient A and B. Other parameters like Molar conductance (Λ
m
), Λ
o

m
and Λ
o

m

η

o
have also been calculated using conductance data. All these parameters show strong evidences of various molecular interactions in terms of ion–solvent and solute–solute interactions. The ion–solvent interactions were supported by isobaric thermal expansion coefficient α

o
. Structure maker/breaker behaviour is explained by Hepler’s constant ((d

2

ϕ

v

o
/dT

2
)
p
), temperature coefficient of B (

d
B
/
d
T

$dB/dT$

) and Walden product’s temperature coefficient (d(Λ
o

m

η

o
)/dT). Further these molecular interactions support structure breaking potential of present studied system.
Klassifizierung von Prozesszuständen beim Bohren
Authors: Flehmke Malte , Romanenko Denys , Rosenthal Oliver , Hendrik Dege Jan 
Published: May 2023

Abstract
Etwa ein Drittel aller Nietbohrungen in der Flugzeugstrukturmontage werden unter Einsatz semi-automatischer Bohrmaschinen gefertigt. Diese Maschinen können mit internen Sensoren ausgerüstet werden, um Prozessdaten aufzuzeichnen. In diesem Beitrag werden zuverlässige und effiziente Methoden zur Klassifizierung von Prozesszuständen basierend auf internen Maschinendaten identifiziert. Diese können für die Implementierung einer intelligenten Prozessüberwachung oder zur Anomaliedetektion verwendet werden.
Mit Künstlicher Intelligenz zu mehr Nachhaltigkeit
Authors: Koch David , Schuseil Frauke , Lentes Joachim , Waltersmann Lara 
Published: May 2023

Abstract
Künstliche Intelligenz (KI) kann zur Auswertung komplexer und großer Datenmengen eingesetzt werden, um Muster zu erkennen und das Verhalten komplexer Systeme vorauszusagen. Hierdurch kann KI auch als Befähiger zur Reduktion von Umweltbelastungen und Optimierung der Nachhaltigkeit produzierender Unternehmen dienen. Dieser Beitrag zeigt das Potenzial der Kombination von Nachhaltigkeit und KI auf, um die Nachhaltigkeitsziele eines Unternehmens zu erreichen. Es wird ein Handlungsleitfaden vorgestellt, der beim Einsatz von KI zur Optimierung der Nachhaltigkeit unterstützt.
Automatisierte Förderanlagenlayoutoptimierung für modulare Fördersysteme
Authors: Pappe Paolo , Stonis Malte 
Published: May 2023

Abstract
Volatile Märkte sowie zunehmende Produktvarianz führen zu komplexeren innerbetrieblichen Materialflüssen. Um diesen gerecht zu werden, ist eine deutliche Steigerung der Flexibilität und Wandlungsfähigkeit vorherrschender Intralogistiksysteme von Nöten. Zur Flexibilisierung der Intralogistik können (kleinskalige) modulare Fördersysteme eingesetzt werden. Hemmnisse für den Praxiseinsatz stellen die geringe Verbreitung sowie die hohen Investitionskosten dar. Um Vorbehalte als auch Risiken zu reduzieren, wurden in einem Forschungsprojekt eine Evaluierungs- und Optimierungsmethode sowie ein anwendungsnahes Planungstool für modulare Förderanlagenlayouts entwickelt. Es befähigt sowohl Planungsdienstleister als auch Anwender, modulare Fördersysteme zu bewerten und deren Potentiale nutzbar zu machen.
Wertschöpfung in Industrie 4.0
Authors: Cramer Simon , Huber Meike , Knott Anna-Lena , H. Schmitt Robert 
Published: May 2023

Abstract
Um das Potential der Daten aus modernen Fertigungsprozessen zu nutzen, sind Investitionen in Infrastruktur und Mitarbeiterausbildung notwendig. Die virtuelle 100 %-Prüfung zeigt wie die Wertschöpfung durch die intelligente Vernetzung von Maschinen, Prozessen und Menschen gesteigert wird. Datengestützte Qualitätsmodelle bilden den Zusammenhang zwischen Prozessdaten und Qualitätsmerkmalen des Produktes ab. Die minutenschnelle virtuelle 100 %-Prüfung führt zu einer frühzeitigen Identifikation von Ausschuss und Prozessschwankungen. Um das Vertrauen in die Qualitätsmodelle zu stärken, wird eine Vorhersageunsicherheit mittels probabilistischer Algorithmen quantifiziert. So kann die Fähigkeit des virtuellen Prüfprozesses analog zu Normen und Standards der Industrie ermittelt werden. Anhand eines Versuchsstands am Werkzeugmaschinenlabor WZL der RWTH Aachen wird die Wertschöpfungssteigerung durch Digitalisierung an einer zweistufigen Prozesskette demonstriert.
Bacteria‐instructed B cells cross‐prime naïve CD8+ T cells triggering effective cytotoxic responses
Authors: García‐Ferreras Raquel , Osuna‐Pérez Jesús , Ramírez‐Santiago Guillermo , Méndez‐Pérez Almudena , Acosta‐Moreno Andrés M , Del Campo Lara , Gómez‐Sánchez María J , Iborra Marta , Herrero‐Fernández Beatriz , González‐Granado José M , Sánchez‐Madrid Francisco , Carrasco Yolanda R , Boya Patricia , Martínez‐Martín Nuria , Veiga Esteban 
Published: May 2023

AbstractIn addition to triggering humoral responses, conventional B cells have been described in vitro to cross‐present exogenous antigens activating naïve CD8+ T cells. Nevertheless, the way B cells capture these exogenous antigens and the physiological roles of B cell‐mediated cross‐presentation remain poorly explored. Here, we show that B cells capture bacteria by trans‐phagocytosis from previously infected dendritic cells (DC) when they are in close contact. Bacterial encounter “instructs” the B cells to acquire antigen cross‐presentation abilities, in a process that involves autophagy. Bacteria‐instructed B cells, henceforth referred to as BacB cells, rapidly degrade phagocytosed bacteria, process bacterial antigens and cross‐prime naïve CD8+ T cells which differentiate into specific cytotoxic cells that efficiently control bacterial infections. Moreover, a proof‐of‐concept experiment shows that BacB cells that have captured bacteria expressing tumor antigens could be useful as novel cellular immunotherapies against cancer.
Non-thyroidal illness syndrome and the prognosis of heart failure: a systematic review and meta-analysis
Authors: Qi Xiaoyi , Qiu Liangxian , Wang Shijia , Chen Xiongbiao , Huang Qianwen , Zhao Yixuan , Ouyang Kunfu , Chen Yanjun 
Published: May 2023

Background
Heart failure (HF) is a complex and multifactorial syndrome caused by impaired heart function. The high morbidity and mortality of HF cause a heavy burden of illness worldwide. Non-thyroidal illness syndrome (NTIS) refers to aberrant serum thyroid parameters in patients without past thyroid disease. Observational studies have indicated that NTIS is associated with a higher risk of all-cause mortality in HF. This meta-analysis aimed to investigate the association between NTIS and HF prognosis.

Methods
Medline, Embase, Web of Science, and the Cochrane database were searched for any studies reporting an association between NTIS and HF prognosis from inception to 1 July 2022. A meta-analysis was then performed. The quality of studies was assessed using the Newcastle–Ottawa Scale. The heterogeneity of the results was assessed with I2 and Cochran's Q statistics. Sensitivity analysis and publication bias analysis were also conducted.

Results
A total of 626 studies were retrieved, and 18 studies were finally included in the meta-analysis. The results showed that NTIS in HF patients was significantly associated with an increased risk of all-cause mortality and major cardiovascular events (MACE), but not with in-hospital mortality. The stability of the data was validated by the sensitivity analysis. There was no indication of a publication bias in the pooled results for all-cause mortality and MACE.

Conclusions
This meta-analysis showed that NTIS was associated with a worse outcome in HF patients. However, the association between NTIS and in-hospital mortality of HF patients requires further investigation.
Comparing inpatient management of chronic pelvic pain flares before and after the COVID-19 pandemic
Authors: Kuan Kevin KW , Neilson Aileen R , Horne Andrew W , Whitaker Lucy HR 
Published: May 2023

Graphical abstract

Abstract
Patients with chronic pelvic pain (CPP) may experience pain exacerbations requiring hospital admissions. Due to the effects of backlogged elective surgeries and outpatient gynaecology appointments resulting from the COVID-19 pandemic, we hypothesised that there would be an increased number of women admitted with CPP flares. We conducted a retrospective review of all acute gynaecology admissions at the Royal Infirmary of Edinburgh from July to December 2018 (pre-COVID) and 2021 (post-COVID lockdown). We collected information on the proportion of emergency admissions due to CPP, inpatient investigations and subsequent management. Average total indicative hospital inpatient costs for women with CPP were calculated using NHS National Cost Collection data guidance. There was no significant difference in the number of emergency admissions due to pelvic pain before (153/507) and after (160/461) the COVID-19 pandemic. As high as 33 and 31% had a background history of CPP, respectively. Across both timepoints, investigations in women with CPP had low diagnostic yield: <25% had abnormal imaging findings and 0% had positive vaginal swab cultures. Women with CPP received significantly more inpatient morphine, pain team reviews and were more likely to be discharged with strong opioids. Total yearly inpatient costs were £170,104 and £179,156 in 2018 and 2021, respectively. Overall, emergency admission rates for managing CPP flares was similar before and after the COVID-19 pandemic. Inpatient resource use for women with CPP remains high, investigations have low diagnostic yield and frequent instigation of opiates on discharge may risk dependence. Improved community care of CPP is needed to reduce emergency gynaecology resource utilisation.

Lay summary
Existing treatments for chronic pelvic pain (CPP) and endometriosis focus on surgery or hormone medication, but these are often ineffective or associated with unacceptable side-effects. As a result, women continue to experience chronic pain and often have ‘flares’ of worsening pain that may lead to hospital admission. The COVID-19 pandemic resulted in backlogged gynaecology clinics and surgeries. The aim of this study was to compare the management of emergency pelvic pain admissions for women with CPP before and after COVID-19. We also aimed to better understand their in-hospital management and estimate their hospital length of stay costs. We did not find an increase in CPP patients admitted for pelvic pain flares after the COVID-19 lockdown. Women with CPP often undergo multiple hospital tests and are often prescribed with strong pain medications which can cause long-term problems. Efforts are needed to improve long-term pain management for women with CPP.
The tipping point for engagement in professional supervision by physiotherapy private practitioners
Authors: Holder Laura , Windross Kiri , Kayes Nicola M. 
Published: May 2023

The aim of this study was to explore the experience and perspectives of physiotherapists working in private practice in New Zealand regarding their decision to engage (or not) in professional supervision (PS). There is a scarcity of research on PS in the physiotherapy profession, despite recommendations by Physiotherapy New Zealand that all physiotherapists should engage in this professional development activity. Using a qualitative descriptive methodology, eight participants were interviewed who identified as either (1) having never experienced PS, or (2) previously but no longer engaged in PS, or (3) currently engaged in PS. Thematic analysis was used to analyse the data. Four themes were constructed: (1) PS and the capitalistic lens, (2) PS is not normal, (3) professional identity and vulnerability, and (4) the relationship in the supervisory context. The drive for increased productivity, cost-effectiveness, and, ultimately, profit continues to dictate practice habits. PS can require the practitioner to share uncertainties about practice, creating a tension in maintaining one's professional identity and credibility which can deter engagement. Balancing professional identity and vulnerability requires the supervisor to create a safe space for recipients to navigate these tensions and sustain their engagement in the process. A significant shift in practice habits and the value ascribed to PS would be required before PS is likely to be normalised as part of physiotherapy private practice culture.
Comparative analysis of 10-year oncological outcomes of robot-assisted radical prostatectomy and radical retropubic prostatectomy. Experience of the Urology Clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry
Authors: Ramazanov K. K. , Kolontarev K. B. , Ter-Ovanesov M. D. , Govorov A. V. , Vasilyev A. O. , Kazakov A. S. , Pushkar D. Yu. 
Published: May 2023

Background. Prostate cancer (PCa) is the 2nd most common oncological disease among men in the world. The first structured program of robot-assisted radical prostatectomy (RARP) was started in the year 2000. In the medical literature, a limited number of studies on long-term oncological treatment outcomes for patients with PCa after RARP is presented. In Russia, the Da Vinci robot was first installed in 2007. In the Urology Clinic of the A.I. Evdokimov Moscow State University of Medicine and Dentistry, the program of robot-assisted surgery was started in November of 2008.Aim. To perform first in Russia evaluation of 10-year oncological treatment outcomes for patients with localized PCa after RARP. To perform comparative analysis with the outcomes of radical retropubic prostatectomy (RRP).Materials and methods. Retrospective analysis of medical histories of 211 patients was performed. Among them, 62 patients did not satisfy the inclusion criteria. The remaining 149 patients were divided into 2 groups: 1st - RARP (n = 82), 2nd - RRP (n = 67). All RARP were performed by the same surgeon, RRP by 2 experienced surgeons.Results. Median follow-up was 110.35 ± 24.58 and 115.19 ± 15.37 months in the 1st and 2nd group, respectively; median follow-up was 120 months in both groups (p >0.05). Survival was calculated using the Kaplan-Meyer approach. Ten-year biochemical recurrence (BCR)-free survival was 79.3 and 82.1 %, clinical recurrence-free survival was 96.3 and 97.1 %, metastasis-free survival was 92.7 and 94.0 %, cancer-specific survival was 93.9 and 95.6 % and overall survival was 85.4 and 86.6 % in the 1st and 2nd group, respectively. Mean time to BCR was 17.00 ± 20.67 and 22.83 ± 26.51 months, respectively ( p >0.05). Calculation of BCR predictors was performed using correlation analysis based on contingency test and Cramer's V-test. In the 1st group, body mass index ≥30 kg/m2 (p = 0.01), prostate-specific antigen level >10 ng/mL (p = 0.04), high progression risk per the D'Amico classification (p = 0.01) were independent preoperative predictors of BCR. Gleason score 7 (4 + 3) (p = 0.04) and ≥8 (p <0.0001) per pathomorphological examination, pT3 stage, extraprostatic extension, invasion into the seminal vesicles and positive surgical margin (all p <0.0001) were independent postoperative predictors of BCR.Conclusion. RARP demonstrates long-term (10-year) oncological effectiveness comparable to oncological effectiveness of RRP in patients with localized PCa.
Phosphate Potential from Septic Tank in Surabaya City, Indonesia
Authors: Ersa Ghina Rizqina , Soedjono Eddy Setiadi , Slamet Agus , Nurhayati Ervin 
Published: May 2023

AbstractPhosphate scarcity will occur if humans do not currently manage the phosphates available in nature with good management. Phosphorus rocks are a natural source of phosphates, whose availability in nature is dwindling due to the large demand for phosphates in the world, especially in agriculture. It is necessary to launch a renewal that involves the recovery of phosphates from fecal sludge. Fecal sludge contains a lot of nutrients that have accumulated from the food we eat. Due to the lack of sewage system distribution in Indonesia, phosphate recovery uses septic tank sludge that has been transported to the Fecal Sludge Treatment Plant. This is one of the potential resources. The purpose of this study was to see the potential (presence) of phosphates in domestic wastewater in Surabaya City, Indonesia. This research was carried out by accidental sampling and the measurement of total phosphate using a spectrophotometer, according to the APHA Method 45001-P standard. The initial characteristics of the sample consisted of liquid phases and solids that were brownish-black and smelly. The phosphate levels in fecal sludge are between 110.42 mg/L and 4572.64 mg/L, with an average value of 1016.77 mg/L. AbstrakKelangkaan fosfat terjadi jika manusia saat ini tidak mengelola fosfat yang tersedia di alam dengan baik. Batuan fosfor adalah sumber fosfat alami, yang ketersediaannya di alam berkurang akibat besarnya permintaan fosfat di dunia, terutama di bidang pertanian. Sehingga diperlukan suatu inovasi baru yang melibatkan recovery fosfat dari lumpur tinja. Lumpur tinja mengandung banyak nutrisi yang terakumulasi dari makanan yang dikonsumsinya. Selain itu, dengan rendahnya sistem pengelolaan air limbah di Indonesia, recovery fosfat dapt dilakukan menggunakan lumpur tinja dari tangki septik yang telah diangkut ke Instalasi Pengolahan Lumpur Tinja (IPLT). Hal ini merupakan salah satu sumber daya yang potensial. Tujuan dari penelitian ini adalah untuk mengukur potensi (keberadaan) fosfat dalam air limbah domestik di Kota Surabaya, Indonesia. Penelitian ini dilakukan dengan pengambilan sampel secara accidental sampling dan pengukuran total fosfat menggunakan spektrofotometer, sesuai standar APHA Metode 45001-P. Karakteristik awal sampel terdiri dari fase cair dan padatan yang berwarna hitam kecoklatan dan berbau. Konsentrasi fosfat dalam lumpur tinja berkisar antara 110,42 mg/L dan 4572,64 mg/L, dengan nilai rata-rata sebesar 1016,77 mg/L.
Morphology and DNA marker for distinguishing Paphiopedilum hangianum and Paphiopedilum emersonii from Vietnam
Authors: Thi Hai Yen Nguyen , Xuan Quang Ngo , Dinh Trong Nguyen , Tien Phat Do , Hoang Mau Chu 
Published: May 2023

Genus Paphiopedilum has species having lovely flowers which are incredibly attractive to everyone. Their ornamental and commercial value caused over-collection and illegal poaching and trade. Due to these reasons, nowadays, the Venus slipper orchids are facing to deplete in nature. Therefore, it is important to consider these species conservation. Mainly, it is necessary to prioritize the identification and phylogenetic analysis methods of the genus Paphiopedilum which includes many species with similar morphological characteristics. Consequently, it isn't easy to distinguish the identical species of this genus when the plants are young or not yet fully flowering. Therefore, this study aimed to distinguish two Paphiopedilum species, i.e. P. hangianum and P. emersonii, which have similar morphological characteristics, through comparative morphological analysis and differences in DNA barcoding sequences. To solve the problem associated with species identifications, a morphological comparison table was created with the four DNA sequence markers matK, rbcL, rpoC1 and trnH-psbA. The results of the morphological analysis showed that P. hangianum and P. emersonii are significantly different from each other in the flower's characteristics. While the difference in leaf morphology of both selected species is found very little, it is also distinguishable upon careful comparison. Moreover, the DNA barcoding indicator gave accurate and rapid distinctions between the two species, even when the plants are young or without flowers. Furthermore, this DNA barcoding can establish an evolutionary relationship between the two selected species and the other species of the genus Paphiopedilum. The results of this study also suggested that the indicator trnH-psbA is a suitable marker for distinguishing these two species and can be applied for the phylogenetic analysis of the genus Paphiopedilum in Vietnam.
Need Assessment on Learning to Teach in Education 4.0 for 21st Century Students’ Learning English Classroom
Authors: Erawati Ika , Sari Eka Dyah Puspita 
Published: May 2023

Many studies address that students’ achievement is encouraged by the effect of teacher professional development. But translating professional development into students’ achievement rarely involves the needs of students. Since there is no one method of need assessment on learning to teach that could fit all situations, picturing students’ point of view of what an English teacher should have would contribute to the needs of teacher professional development. Therefore, this study attempted to reveal the essential issue on engineering students’ perception toward the learning to teach in Education 4.0 that teacher should comply. A descriptive study was conducted to describe and analyze the need of teacher professional development (TPD) for the students’ learning in the
21st century from students’ point of view. Interview and questioner were implemented to complete the objective of the study. The
data collected which was gathered from 90 students as the population sample were analyzed into statistical analysis. Based on the finding, this current study clarified that teacher professional development, especially for English teachers in occupying 21st century students’ learning needed to meet the competency of pedagogic, professional, personality, and social. The finding also showed that professional competence needed to be more considered for teacher professional development. The result obtained of this study is expected to contribute to the existing literature on professional development of ELT teachers for engineering students and also open wide opportunity for future research to conduct further study.
POSSIBILIDADE DE INSERÇÃO DA EDUCAÇÃO PARA CARREIRA NO ENSINO SECUNDÁRIO:
Authors: Choe Joao Francisco de Carvalho 
Published: May 2023

O presente artigo tem como tema possibilidade de inserção da educação para carreira no ensino secundário. De carácter exploratório, descritivo e de natureza qualitativa, a pesquisa em relato teve como objectivo reflectir sobre a possibilidade da inserção da educação para carreira no ensino secundário em Moçambique. Foram participantes desta pesquisa 16 sujeitos. Como instrumento de recolha de dados foi usado um guião de entrevista. O guião da entrevista para os alunos foi composto por 6 perguntas enquanto que o dos professores integrava 7 questões. A análise das entrevistas realizadas baseou-se na análise de conteúdo, que foi sistematizada em seis (6) categorias. Os resultados da pesquisa foram obtidos através de relatos dos dois subgrupos que evidenciaram que não existem programas de OPC na Escola onde o estudo foi realizado. Quanto a possibilidade, pertinência de inclusão dos programas de OPC no sistema escolar observou-se que tanto quanto professores quanto alunos consideram que há necessidade de se implementar acções e programas de educação de carreira na sua escola.