bluuebunny/crossref_metadata_2025_split huggingface dataset:
Streamflow forecasting for the Hunza river basin using ANN, RNN, and ANFIS models
Authors: Khan Mehran , Khan Afed Ullah , Khan Jehanzeb , Khan Sunaid , Haleem Kashif , Khan Fayaz Ahmad 
Published: April 2023

Abstract

Streamflow forecasting is essential for planning, designing, and managing watershed systems. This research study investigates the use of artificial neural networks (ANN), recurrent neural networks (RNN), and adaptive neuro-fuzzy inference systems (ANFIS) for monthly streamflow forecasting in the Hunza River Basin of Pakistan. Different models were developed using precipitation, temperature, and discharge data. Two statistical performance indicators, i.e., root mean square error (RMSE) and coefficient of determination (R2), were used to assess the performance of machine learning techniques. Based on these performance indicators, the ANN model predicts monthly streamflow more accurately than the RNN and ANFIS models. To assess the performance of the ANN model, three architectures were used, namely 2-1-1, 2-2-1, and 2-3-1. The ANN architecture with a 2-3-1 configuration had higher R2 values of 0.9522 and 0.96998 for the training and testing phases, respectively. For each RNN architecture, three transfer functions were used, namely Tan-sig, Log-sig, and Purelin. The architecture with a 2-1-1 configuration based on tan-sig transfer function performed well in terms of R2 values, which were 0.7838 and 0.8439 for the training and testing phases, respectively. For the ANFIS model, the R2 values were 0.7023 and 0.7538 for both the training and testing phases, respectively. Overall, the findings suggest that the ANN model with a 2-3-1 architecture is the most effective for predicting monthly streamflow in the Hunza River Basin. This research can be helpful for planning, designing, and managing watershed systems, particularly in regions where streamflow forecasting is crucial for effective water resource management.
Assessing the characteristics of different-sized particles in the first flush of roof runoff
Authors: Zhang Wei , Qu Peizhen , Sun Huichao , Che Wu 
Published: April 2023

Abstract

The first flush occurs during urban runoff events. In this study, we aimed to assess the characteristics of different-sized particles in the first flush of roof runoff, and runoff was collected from an asphalt roof (AR), metal roof (MR), and cement roof (CR) for analysis. There were no clear patterns in the particle size distributions in the runoff from the three roofs and were affected by several factors. The strength of the first flushes differed significantly for particles in different size categories in AR, MR, and CR runoff and were very different from suspended solids (SS). The comparison showed that it would be possible to meet the SS control design expectation required by the Chinese national standard for runoff pollution control (VFF = 3 mm) for particles &lt;45 μm but not for particles &gt;45 μm. The methods presented provide an alternative for assessing the ability to control the transport of different-sized particles in runoff.
Evaluation of ultrasound examination informativity in diagnosing retinoblastoma
Authors: Artemenko Yu. V. , Panferova T. R. , Ushakova T. L. , Mikhailova E. V. 
Published: April 2023

The aim of this work is to evaluate the informativity of the ultrasound (US) in detecting retinoblastoma (RB) and the local invasion of the tumor in children using modern multi-purpose ultrasound scanners.Materials and methods. This study included 108 patients (216 eyes) examined for suspected RB. RB was diagnosed in 91 patients, 60 children had unilateral tumor, 31 – bilateral tumor (122 eyes). In the remaining 17 children (20 eyes damaged), different non-tumor pathology of the eye was revealed. Among 122 eyes affected by RB, 51 were removed with subsequent histological examination. 27 eyes were removed before treatment, 24 – after chemotherapy.Results. In our study the informativity of ultrasound in detecting RB are: sensitivity – 98.4 %, specificity – 96.8 %, accuracy – 97.7 %. Sensitivity, specificity and accuracy in assessing tumor invasion to the anterior segment of the eye are 36.4 %, 95.0 % and 82.4 % respectively, to the vitreous body – 97.7 %, 100 % and 97.9 %, to the optic nerve – 54.5 %, 57.1 % and 54.9 %.Conclusion. US examination using linear transducers of 9–18 MHz is highly informative in detecting RB, however, some indicators of the effectiveness in assessing local invasion are not high enough, due to the technical possibilities of the method. One possible way to improve the informativity – to use deep sedation during US examination.
Acne disease in germ cell tumors. A brief review of the literature and a description of our own clinical observation
Authors: Martynov D. V. , Belysheva Т. S. , Valiev Т. Т. , Kapkova O. A. , Sharapova E. V. , Prokofyev A.  A. , Vishnevskaya Ya. V. , Mikhailova E. V. , Panferova T. R. , Varfolomeeva S. R. 
Published: April 2023

malignant neoplasms (MNP). The frequency of PNS in MNP ranges from 1 to 20 % according to different authors. One of the manifestations of PNS is acne, which occurs against the background of malignant neoplasm due to hormonal disorders.The presented article describes a clinical case of a patient with a mixed germ cell tumor and metastases in the retroperitoneal lymph nodes. The germ cell tumor produced human beta-chorionic gonadotropin, which led to the development of acne as a PNS.Antitumor treatment (surgical removal of the tumor and polychemotherapy) normalized the levels of human beta-chorionic gonadotropin and serum testosterone, which in turn led to regression of acne without acne therapy.
Prevalence and Severity of Chronic Kidney Disease in Haiti
Authors: Roberts Nicholas L.S. , Pierre Jean L. , Rouzier Vanessa , Sufra Rodney , St-Preux Stefano , Yan Lily D. , Metz Miranda , Clermont Adrienne , Apollon Alexandra , Sabwa Shalom , Deschamps Marie M. , Kingery Justin R. , Peck Robert , Fitzgerald Daniel , Pape Jean W. , Tummalapalli Sri Lekha , McNairy Margaret L. 
Published: April 2023

Background
CKD is a major cause of morbidity and mortality in lower-income countries. However, population-based studies characterizing the epidemiology of CKD in these settings are lacking. The study objective was to describe the epidemiology of CKD in a population-based cohort in urban Haiti, including estimates of the prevalence by CKD stage, the magnitude of associated factors with CKD, and the proportion on guideline-recommended treatment.

Methods
We assessed the prevalence of CKD and associated risk factors in the population-based Haiti Cardiovascular Disease Cohort. We analyzed cross-sectional data from 2424 adults who completed a clinical examination, risk factor surveys, and laboratory measurements for serum creatinine, urinary albumin, and urinary creatinine. We compared our results with US estimates from the National Health and Nutrition Examination Survey. CKD was defined as either a reduced eGFR <60 ml/min per 1.73 m2 or urinary albumin-to-creatinine ratio ≥30 mg/g according to the Kidney Disease Improving Global Outcomes guidelines. Multivariable logistic regression identified associated factors with CKD.

Results
The mean age was 42 years, 57% of participants were female, and 69% lived in extreme poverty on ≤1 US dollar per day. The age-standardized prevalence of CKD was 14% (95% confidence interval [CI], 12% to 15%). The age-standardized prevalence of reduced eGFR and elevated urinary albumin-to-creatinine ratio was 3% (95% CI, 2% to 4%) and 11% (95% CI, 10% to 13%), respectively. Diabetes (adjusted odds ratio, 4.1; 95% CI, 2.7 to 6.2) and hypertension (adjusted odds ratio, 2.9; 95% CI, 2.0 to 4.2) were significantly associated with CKD. Only 12% of participants with CKD and albuminuria were on guideline-recommended agents, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers.

Conclusions
In a large population-based cohort of Haitian adults, CKD was highly associated with both diabetes and hypertension. The proportion of participants with CKD on treatment was low, underscoring the need for strengthening clinical management and nephrology care health infrastructure in Haiti.

Clinical Trial registry name and registration number:
A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti, NCT03892265.
Ethosomes: A Vesicular Carrier as a Novel Tool for Transdermal Drug Delivery System
Authors: Devaki Jorapur , Pavuluri Satish , Suma Naduvinamani 
Published: April 2023

In recent years, nanotechnology has a new era of drug delivery for many drug systems. Transdermal drug delivery is one of the few systems that have recently become a major focal point of research. When compared to traditional drug delivery systems, the Transdermal Drug Delivery System (TDDS) has various advantages. Due to the barrier properties of the Stratum Corneum, TDDS has had limited market success. The introduction of ethosomes, which are soft, malleable vesicular carriers containing ethanol and are tailored for enhanced delivery of active agents, has opened up a new area of vesicular research for transdermal drug delivery. According to various reports, ethosomes have a promising future in improving the efficacy of transdermal delivery of various agents. Ethosomes are also useful for the non-invasive delivery of small, medium and large drug molecules. Ethosome preparation is simple, requires no complicated equipment, and can thus be scaled up to industrial levels. The review emphasises introduction to ethosomes, their composition and preparation methods, evaluation, and their efficiency in penetrating the skin and the use of ethosomes in transdermal medication delivery as being more effective than liposomes or hydroalcoholic solution in terms of quantity and depth.
Keywords: Ethosomes, Novel carriers, Transdermal Drug Delivery System
Herbal Drug Standardization: A Systemic Review
Authors: Lamichhane Suman , Sahariah Bhargab Jyoti , Das Bhaswati , Khatiwara Deepika , Sola Piyong , Adhikari Rudra Prasad , Gogoi Bitu , Alam Tahid 
Published: April 2023

The demand for herbal medicinal products and materials is rising, and maintaining their quality is therefore becoming increasingly important. Numerous physical, chemical, and geographical factors that affect these materials' quality also affect the quality of the herbals. In addition, the quality of herbal materials is becoming increasingly a concern due to adulteration. The quality characteristics of the herbal material the herbal pharmaceuticals are assessed using a variety of chemical and phytochemical tests, analytical techniques, and hyphenated analytical techniques. Formulations made from herbs are now widely accepted as effective treatments for many ailments. the creation of reliable analytical techniques, such as quantitative assessments of marker/bioactive chemicals and other techniques, that can accurately profile the phytochemical makeup. For the manufacture and manufacturing of herbal medications, standardisation is a crucial step in establishing a uniform biological activity, consistent chemical profile, or even just a quality assurance programme. It is crucial to follow WHO-specific recommendations for evaluating the quality, safety, and efficacy of herbal medicines as a condition for worldwide harmonisation. An overview of the numerous methods used for the extraction, characterisation, and standardisation of herbal nanomedicines is presented.
Keywords: herbal drugs, standardization, herbal formulation, quality control
Morphometric and molecular sequencing evidence for the identification of Artemia franciscana (Kellogg, 1906) in Southern India
Authors: Biju Y. , Krishnakumar S. , Krishnaveni M. 
Published: April 2023

A native of North America, the brine shrimp Artemia franciscana is now a very invasive foreign species that has already been imported to most of the world. Before the introduction of A. franciscana, Asia was home to a wide range of bisexual Artemia species, which is no longer the current case. The collected Artemia samples from salt pans in south India were subjected to exact species identification and determination of phylogeographic origin through morphometric and molecular phylogenetic analysis. The Artemia species was validated with the observation of spiny subspherical frontal knob and distinctive lateral triangular ovisac lobes with projections on its body. The phylogenetic analysis of these Artemia species from two sampling localities was carried out after nucleic acid sequencing. After DNA barcoding of the cytochrome oxidase COI gene, the samples were identified as belonging to A. franciscana.
Study on photoperiodic modulation of the female fertility of Drosophila biarmipes
Authors: Shamim Ahmed Malik , Sayed Zarin Sana 
Published: April 2023

Various attributes of light, including the intensity, spectral composition and duration of the photophase, have been documented to have remarkable influence on all aspects of behaviour and physiology of eukaryotic experimental models. This hypothesis was investigated in the present study wherein the effects of photoperiod varying from 6 to 18 h of 24‑h light-dark (LD) cycles was examined on the lifetime fertility (i.e., the viable F1 progeny) of females of the Indian fruit fly, Drosophila biarmipes. The flies were subjected to six types of 24‑h LD cycles (light at 150 lux and dark at 0 lux in all LD cycles) in which the photoperiod varied from extremely short (6 h) to extremely long (18 h) duration. The female fertility was the highest in photoperiods of 10, 12 and 14 h, moderate in 8 and 16 h and the lowest in 6 and 18 h. These results indicate that the performance of the circadian system is at its optimum when it is maintained in zeitgeber cycles wherein the photoperiod is close to that of the natural day of the tropical or sub-tropical region from where the given species or strain originated. This study has great implication in predicting the insect abundance at a particular season of the year when the photoperiod is conducible for optimum reproduction. Such premonition should help the local administrative bodies to take appropriate control measures against the given insect pest and vector insects.
Problems of Formation of the Investment Climate in the Republic of Dagestan
Authors: Kugai A. I. , Jamalov M. Sh. 
Published: April 2023

Aim. Formulate proposals to improve the state policy of entrepreneurship development and investment climate in the Republic of Dagestan.Tasks. To study the current state of the investment climate and entrepreneurial activity in the Republic of Dagestan. Consider international experience of interaction between business and public authorities. Determine the main direction in the activities of state and municipal authorities, civil society institutions and the business community of the Republic of Dagestan to create a favorable investment climate in the republic.Methods. The work uses the methods of social constructivism, institutional, structural-functional and comparative analysis, statistical, as well as formal-logical research methods.Results. According to the data obtained, the investment sector of the region’s economy needs some improvement. There is a negative dynamics of investments in the fixed capital of the republic, as well as a decrease in the volume of investments per capita in recent years. Data for 20 19–2021 show an increase in the volume of public investment, while the volume of private investment in the fixed capital of the republic is significantly decreasing.Conclusions. The authors suggest that the authorities authorized in the field of entrepreneurship and investment focus on the information technology direction of investment activity development. It is recommended to improve and actively promote the recently created investment map of the Republic of Dagestan, to ensure the creation of mechanisms for updating it and filling it with new content, which will significantly modernize investment activities and bring it to a qualitatively new level. The largest capital in the stock market is made during periods of recession, thanks to the investment and navigation map. It’s just that people don’t notice it in a crisis.
About BRICS Investment Arbitration
Authors: Skvortsov O. Yu. 
Published: April 2023

The article discusses the issue of creating investment arbitration in the BRICS member states. The prerequisites for the creation of this institution are the problems of “classical” investment arbitration, which, in turn, are predetermined by the crisis of globalism as an idea of the world order.Aim. The purpose of this work is to study the prerequisites and the possibility of creating investment arbitration in the BRICS countries.Tasks. Within the framework of achieving this goal, the following tasks were solved: analysis of the crisis of the idea of globalism and, as a consequence, the crisis of “classical” investment arbitration; analysis of the regionalization of legal institutions in general and investment arbitration, in particular; analysis of the conditions for the creation of investment arbitration in the BRICS member states.Methods. The methodology of solving the formulated tasks is based on the identification of those patterns that are characteristic of various periods of the existence of world political, economic and legal relations.Results. The prerequisites for the creation of BRICS investment arbitration are the problems of “classical” investment arbitration. The author concludes that this crisis entails a tendency to regionalize both communities of states and legal institutions that ensure the functioning of these unions. Hence, there is a need for the formation of regional arbitrations. Since the BRICS community has set as its goal the formation of a coordinated financial, trade and investment policy, it also required the appropriate jurisdictional support of these processes. In addition to the creation of other institutions, the economic needs of the BRICS require the creation of investment arbitration, which should become a mechanism for resolving investment disputes arising between various economic entities.Conclusions. It is concluded that when creating investment arbitration, it is necessary to abandon the ideology of protecting exclusively the rights of the investor, which has become the dominant idea in matters of economic law and order. In particular, it is necessary to take into account the interests of public entities — recipients of investments. These interests lie in the plane of protecting human rights, public needs, and environmental problems. In addition, it is necessary to abandon the exclusive use of the Anglo-Saxon legal technique, which is imposed within the framework of the existing investment arbitration. In the end, the conclusion is made about the relevance of the creation of the BRICS investment arbitration, that this institution will contribute to the strengt hening and development of ties betw een the states participating in this association.
Experiencia del componente práctico del curso de proyecto de diseño I
Authors: Romero Cuellar Javier Augusto , Pérez Cardona Carmen Adriana 
Published: April 2023

The training of industrial designers based on the virtual and distance modality creates a synergy that allows us to chart a new course in education, this is part of the transformation and social mobility of millions of people, this modality is important within our educational process, managing to reach many places where training cannot be accessed and especially in industrial design, being able to bring design closer to many people and contexts is an important challenge that the program has outlined, for this strategies have been implemented which have allowed different students from the territory have access to training.

This article exposes some of the results of the exercise of carrying out the development of the practical component of the Design Project I course in the virtual modality.
Ecosistemas digitales en las redes globales de valor: una aproximación desde el análisis de decisiones multicriterio
Authors: Figueroa Peinado Woody , Vásquez Bernal Oscar Alejandro , Pinzón Hoyos Benjamin , Diaz Pulido José Martín , Gómez Méndez José Daniel 
Published: April 2023

This paper shows a progress result of the ongoing research on the application of the multi-criteria decision-making Methodology (MCDM) and the Analytical Hierarchy Process (AHP) that allows for defining the most appropriate model in the measurement of the degree of maturity of global value chains, based on the methodological phases for decision making, through the analysis of existing measurement systems recognized worldwide, that allow selecting the alternatives and their attributes for comparison. In this phase of the research, the incidence of industry 4.0 in the processes of integration of supply chains for the conformation of digital ecosystems is highlighted, its incidence in the adaptive configurations of value chains, and the contribution of technology in the maturity of the same.
Evaluation of swallowing in transverse maxillary deficiency patients before and after rapid maxillary expansion
Authors: Yalcin Aycan , Aras Isil , Gode Sercan , Durusoy Duygu , Sezgin Baha , Eyigor Sibel , Aras Aynur 
Published: April 2023

ABSTRACT

Objectives
To evaluate swallowing function in relation to oropharyngeal dysphagia (OD) in adolescents who had transverse maxillary deficiency with posterior crossbite and high-arched palate, before, and after rapid maxillary expansion (RME).

Materials and Methods
Twenty patients (mean age: 13.0 ± 3.1) with bilateral posterior crossbite and high-arched palate (RME group: RMEG) and 20 volunteers (mean age: 13.4 ± 2.6) with Class I crowding without posterior crossbite or high-arched palate (control group: CG) were recruited. OD signs and symptoms were evaluated using the Eating Assessment Tool-10 (EAT-10) questionnaire, patient complaints, and physical examination of swallowing function before (T1) and 7 months after (T2) RME. Additionally, fiberoptic endoscopic evaluation of swallowing (FEES) with water, yogurt, and cracker was performed. In CG, evaluation of swallowing was performed only once, corresponding to T1 of RMEG.

Results
Prevalence of OD signs and symptoms based on patient complaints and physical examination of swallowing was low (5%–15%), and nonsignificant differences were observed between CG and RMEG at T1 for these parameters as well as for EAT-10 scores. Total post-swallow pharyngeal residue with yogurt was significantly different between CG and RMEG at T1, with a prevalence of 60% in RMEG (P &lt; .05). There was no significant difference regarding residue with yogurt between T1 and T2 in RMEG (P &gt; .05).

Conclusion
Patients with a maxillary transverse deficiency were affected by pharyngeal residue as indicated by FEES, but it did not appear to improve in short-term follow-up in patients treated with RME.