bluuebunny/crossref_metadata_2025_split huggingface dataset:
An actinomycete strain of Streptomyces sp. Je 1-93: a producer of antifungal antibiotics
Authors:   Ivan Franko National University of Lviv, Tistechok S. , Fedorenko V. ,   Ivan Franko National University of Lviv, Gromyko O. ,   Ivan Franko National University of Lviv
Published: March 2023

Screening new naturally occurring biologically active compounds is an effective strategy for creating a portfolio of platforms for developing new chemical agents against multidrug-resistant microbial strains. Actinomycetes are an extremely prolific source of structurally diverse secondary metabolites, most of which have pharmaceutical or biotechnological significance. Among them, the genus Streptomyces stands out, producing about 55 % of all known naturally occurring antibiotics. However, due to the significant redisco­very of already known compounds, especially among actinomycetes, the rate of discovery of new antibiotics has slowed considerably. Today, there is growing interest in screening biologically active compounds from poorly studied and extreme habitats. In this study, we demonstrated the phylogeny, bioactivity and dereplication of secondary metabolites of the Je 1-93 strain isolated from the rhizosphere soil of juniper (Juniperus excelsa Bieb.). Phylogenetic analysis of the Je 1-93 strain based on the nucleotide sequence of the 16S rRNA gene allowed its identification in the Streptomyces genus and showed the greatest similarity with the S. hydrogenans CA04 strain (100 % identity). Analysis of the antimicrobial activity of this strain showed its strong antifungal activity against the reference Candida albicans ATCC 885-653 strain as well as the multi-resistant C. albicans №12 strain, which is resistant to nystatin, amphotericin B, clotrimazole, itraconazole, ketoconazole and fluconazole. To identify compounds that probably provide antifungal activity, we analysed secondary metabolites produced by Streptomyces sp. Je 1-93. To facilitate dereplication, the obtained extracts of secondary metabolites were separated by size-exclusion chromatography on a column filled with Sephadex LH-20. Methanol was used as the mobile phase. As a result of the dereplication analysis in the database of natural compounds (Dictionary of Natural Products), antibiotic antimycins were found among the secondary metabolites in the extract of the Je 1-93 strain, and they have a high probability of providing the antifungal activity of this strain.
FEATURES OF ORGANIZING ACTIVE RECREATION IN INSTITUTIONS OF HIGHER EDUCATION BY MEANS OF PHYSICAL EDUCATION
Authors: Boyko G. , Sharafutdinova S. , Muravsʹkyy L. 
Published: March 2023

The article analyzes the peculiarities of the organization of active recreation in institutions of higher education by means of physical education. In the realities of our time, active recreation of students is important and has a positive effect on the body of those who are engaged. After all, the motor activity of students has noticeably decreased due to a number of reasons. Active introduction of sports and physical culture and health facilities into the daily routine (morning hygienic gymnastics, volleyball, basketball, football, boating, walks to the forest) 70-90% of those who practice improve their well-being. Therefore, it is important to pay more attention and work to the organization of active recreation of student youth in order to prevent hypodynamia.
Recreational facilities of Ukraine have already accumulated considerable work experience, which, confirming the conclusions of scientists, provides rich practical material. Important are the conclusions that staying in physical culture and health camps significantly increases vacationers' interest in physical culture. Summer and winter holidays have become traditional in recreation facilities. their programs are meaningful and interesting, filled with sports competitions, fun rides, sportsmanship demonstrations, social gatherings for sports games, rowing, and more. The means of therapeutic gymnastics are: structural exercises, types of movements and dance steps, exercises for general development with and without objects, exercises on the gymnastic wall, bench, with a rope, on special devices, applied exercises; special balance and breathing exercises, coordination, stretching, corrective exercises, etc.
When choosing exercises for classes, take into account the nature of the disease, physical fitness, gender and age of the vacationers. Therapeutic gymnastics classes are individual and group. They are conducted according to the generally accepted scheme, which consists of preparatory, main and final parts. Games occupy a significant place in the system of physical education. One of their varieties is mobile games.
Training of future physical therapists to job with clients with disorders of the cardiovascular system
Authors: Kyi O. G. , Volkova S. S. 
Published: March 2023

The article is devoted to the study of the problems of the training of physical therapists associated with the formation in students of a sufficient amount of knowledge and skills in etiology, diagnosis of deviations in the health of patients with disorders of the cardiovascular system, means and methods of physical therapy.
The revealed topics are presented in the program of training students in the methods and technologies of working as a physical therapist with clients who have diseases of the cardiovascular system.
As a result of studying the discipline, the student should know:

basic concepts of general nosology;
the role of factors, conditions and reactivity of the body in the occurrence, development and termination of diseases of the cardiovascular system;
causes and mechanisms of diseases of the cardiovascular system, their manifestations and prognosis for the body during their development;
etiology, pathogenesis, manifestations and consequences of the most frequent diseases of the cardiovascular system, principles of their etiological and pathogenetic therapy;

– the value of the experimental method (modeling of diseases and painful states) in the study of diseases of the cardiovascular system; its possibilities, limitations and prospects.
The student should be able to:
– analyze clinical and laboratory, experimental and other data and formulate possible causes and mechanisms of development of diseases of the cardiovascular system based on them;

apply the acquired knowledge when studying other clinical disciplines in further treatment and prevention activities;

to analyze the problems of diseases of the cardiovascular system from the point of view of critical assessment of modern theoretical concepts and trends in medicine;

to interpret the results of the most common methods of diagnosing diseases of the cardiovascular system;

solve situational problems;
skillfully conduct system surveys and collect history;
to be able to conduct a physical examination, knowing the techniques of palpation, percussion and auscultation;
by the nature of the temperature curve, determine the type of fever in inflammatory diseases of the cardiovascular system;

interpret the results of basic diagnostic allergy tests;
substantiate the principles of pathogenetic therapy of the most common diseases of the cardiovascular

The content of the lecture material is revealed. The results of the survey of 38 students on 12 questions are presented. 100% of the surveyed students connected this discipline with the general field of study and felt the need to study it for their future work in the field. The material offered to students contributes to their preparation for work as a physical therapist with clients who have diseases of the cardiovascular system.
The question of the formation of motor actions in students of higher education in the conditions of distance learning
Authors: Cherevko S. , Dorosh V. , Lutaeva N. , Umerenko V. , Cherevko А. 
Published: March 2023

The authors of the article collected and analyzed the materials of scientific works that investigate the problems of organizing the educational process in the discipline of Physical Education, the formation of motor skills and their relationship with the level of physical fitness of students of higher education in the conditions of distance learning. Global transformations in the spheres of development of scientific, legal, programmatic and normative foundations of the educational system in Ukraine are aimed at creating an educational space focused on self- education, self-development and self-improvement of a person. The activity in the process of learning new motor actions has a special applied learning and cognitive character, and the effectiveness of learning is largely determined by the ability of the teacher to organize the learning process in accordance with physiological, psychological, pedagogical and structural laws, which are the basis of modern theories and technologies of learning. The terms "technology", "motor task", "motor skills", "motor skills" are tools for learning and transforming the surrounding world through action (movement) [1]. Using a certain teaching method, the physical education teacher focuses on the individual capabilities of a person, his abilities, therefore, for each person, the methods of educational activity must be different, and the pace of pedagogical steps will also be different. It should be noted that the system of higher education of the country currently lacks pedagogical technologies capable of solving the problems of physical education in the conditions of distance education.
If students do not acquire the necessary level of knowledge and motor skills in general educational institutions with a distance form of education, further education in institutions of higher education practically does not solve the problems of forming motor skills and skills, since adolescence is a period of motor improvement of motor abilities, greater opportunities for the development of motor skills.
Peningkatan Peluang Bisnis Strategi Industri Migas Terhadap Pengaruh Pandemi Covid-19 Di Indonesia
Authors: Edy Soesanto  , Rasyid Aly , Bobby Devagan  
Published: March 2023

The oil as well as fuel market participates in an essential function in the Indonesian economic climate, as an income source APBN as well as a resource of power (particularly gas) towards steer different industries of lifestyle throughout Indonesia. Limitations on individual motion have actually resulted in a straight decrease popular for gas. Along with reducing usage, Covid-19 likewise has actually an effect on reducing oil as well as fuel costs as well as manufacturing, consisting of ceasing upstream tasks as well as decreasing fine-tuning tasks. Within this particular examine, monitorings were actually made from all of upstream oil as well as fuel company tasks in Indonesia particularly, since the effect of the Covid-19 pandemic consisted of the effect of worldwide problems overall, to ensure that healing initiatives could be created in addition to recommendations for handling problems that might intensify. The outcomes of this particular examine end that the avoidance of the effect of Covid-19 for the upstream oil as well as fuel company should be actually performed comprehensively as well as includes all of stakeholders, to ensure that the oil as well as fuel market can easily remain to make it through amidst the direct visibility of the Covid-19 pandemic.
Reference:
Dito Aditia Darma, et all, Dampak Pandemi Covid-19 Terhadap Perekonomian Indonesia, Jurnal
Benefita 212-224, Juli 2020.
Nugroho, H. (2018a). Pemikiran Mengenai Pembangunan Industri Gas Bumi Indonesia. Depok : Institute of Development & Energy Economics.
Nugroho, H. (2018b). Reserves and security of our energy supply, dalam Thoughts on Indonesian Energy Issues & Policies. Jakarta : Bappenas
Nur Laila Widyastuti, et all, Dampak Covid-19 terhadap Industri Minyak dan Gas Bumi:
Rekomendasi Kebijakan untuk Indonesia, The Indonesian Journal of Development Planning Volume IV No. 2 – Juni 2020.
Republik Indonesia, (2020). Anggaran Pendapatan & Belanja Negara https://www.kemenkeu.go.id/informasi-publik/uu-apbn-dan-notakeuangan/, diakses pada tanggal 10 September 2020.
SKKMIGAS, https://www.skkmigas.go.id/publikasi/infographic, di akses pada tanggal 20 Oktober 2020.
Tirto.id Website, Update Corona Indonesia April 2020, https://tirto.id/update-corona-indonesia-21-april-2020-data-covid-19-dunia-terkini-ePYZ, diakses tanggal 21 April 2020.
A FUZZY SEMI_ESSENTIAL SUBMODULE OF A FUZZY MODULE
Authors: Abbas Hussein H , Al-Aeashi Shukor Neamah 
Published: March 2023

In this paper, we introduce the concept of fuzzy semi-essential (large)Â submoduleÂ , and we studyÂ a necessary and sufficient condition for a fuzzy submodule of a fuzzy moduleÂ to be a fuzzy semi-essential (large)Â submoduleÂ , also fuzzy images and fuzzy inverse-images of generalized fuzzy semi-essential (large)Â submodule are studied.
Anew method for speeding up FractalCompression using different value of affine transformation and highest gray value of pixel
Authors: Mohammed Hind Rostom , Ali Hanaa Muhsen 
Published: March 2023

In this paperÂ new algorithm forÂ speeding up fractal image compression Â is presented. A new adapted method based on computing the highest value of the pixel of the image to reduce the computational complexity in the encoder stage and which are led to decreasing the encoding time while the reconstructed image from the work as good as we want. For increasing the effectiveness of search stage we used another type of partitioning method that led to increase the flexibility of range partition, this method is HV-partition. We applied this method on images and also present a comparison of this method against other method which used to speed the fractal compression.
Mughal Heritage in Delhi: Toponymics Manipulation
Authors: Kozlova Alexandra A. 
Published: March 2023

In the post-colonial world, when new nations one after another gained independence and got out of the colonialists hand, “toponymic games” have become a global phenomenon. The main goal of such manipulations was to return historical justice, to remove associations with the oppressive past from the collective memory of citizens. Post-colonial India was also affected by renaming stir at various levels. Toponyms associated with Muslim dynasties began to undergo changes at the most.
Muslim dynasties ruled India from the XIII to the mid XIX century. Over this long period of time, they had a great impact on the history and culture of India. Muslim influence especially affected the capital city of Delhi. This significant historical period is also reflected in the toponymy of the city. The article shows how the names of streets associated with the history of Mughal India are being erased from the map of Delhi and from the memory of the inhabitants of Delhi in recent years (often it’s being done at the initiative of politicians affiliated with the pro-Hindu BJP). Each year the New Delhi Municipal Committee receives more than 300 street and park renaming requests. Aurangzeb Road in New Delhi (which name was changed to A.P.J. Abdul Kalam Road in August 2015) was the first to be renamed. In an effort to make nice with the Hindu majority, rename claims are on the rise during India’s election campaigns. Nonmuslims say that all the troubles of the country came to the fore as the result of the Muslim invasion. So, the point of street rename is not in the dissonance of toponyms themselves, but in their meaning.
محمد حديد ودوره في تاريخ العراق السياسي المعاصر (1946- 1963)
Authors: جميل رشا هشام 
Published: March 2023

تكمن أهمية البحوث التاريخية لدورها ومساهمتها في شتى المجالات السياسية والثقافية والاجتماعية ولاسيما الخاصة بالسيرة الذاتية للشخصيات الوطنية، ويعد محمد حديد إحدى تلك الشخصيات والتي كان لها دور كبير في بناء الدولة العراقية ومساهمته في صناعة الأحداث التاريخية من خلال حقيقتين أساسيتين مثلت تاريخ العراق المعاصر وهما الملكية ودخوله للحزب الوطني الديمقراطي عام 1945، ومن ثم الجمهورية أبان فترة حكم عبد الكريم قاسم وقيام ثورة 14 تموز 1958 وما صاحب كليهما مجتمعاً ومنفرداً من سلبيات وايجابيات في مختلف المجالات السياسية والاقتصادية والاجتماعية والتي أثرت بشكل أو بآخر على المجتمع العراقي في ذلك الوقت.
وأما الأسباب التي دعت إلى اختيار موضوع البحث فيكمن ايجازها بقلة الكتابات عن هذه الشخصيّة الوطنية والتي كان لها دور كبير في صياغة ووضع العديد من القرارات والقوانين المهمة من الجانب السياسي والاقتصادي والاجتماعي والصناعي في العراق فقد تم استحداث وزارة الصناعة ولأول مرة بعد قيام ثورة 14 تموز 1958 وايجاد صيغ جديدة للتعامل مع شركات النفط الأجنبية وخروج العراق من الكتلة الاسترلينية، وقد اعتمدت على منهج البحث العلمي المعتمد في كتابة البحوث التاريخية.
الأسباب الاجتماعية للطلاق العاطفي بين الزوجين
Authors: عبد اللطيف هديل فرحان , علي بروين حسين 
Published: March 2023

ظهرت في الأسرة الجديدة مشكلة الطلاق العاطفي بين الزوجين، والتي أصبحت تسري في كيان الحياة الزوجية وذات أثر سيء على استقرار الأسرة، ومستقبل الزوجين، والأبناء وهي من المشكلات المسكوت عنها في المجتمع العربي عامة والمجتمع العراقي خاصة بغية المحافظة على الابناء او الوجاهة الاجتماعية، لذا تناولت دراستنا موضوع الطلاق العاطفي بهدف التعّرف على الأسباب المؤدية اليه، والتوصل الى بعض المعالجات او المقترحات بهدف التقليل او الحد من هذه المشكلة بين الزوجين، ولأجل التحقق من اهداف الدراسة قمنا باختيار عينة بلغ حجمها (240) زوجة، وتمثلت العينة بالعشوائية الطبقية التي عكست خصائص مجتمع الدراسة الا وهو مجتمع مدينة بغداد بجانبيها الكرخ (المنصور، وشهداء البياع الشرطة الرابعة)، والرصافة (شارع فلسطين، وحي الأمين) وتعد هذه الدراسة دراسة وصفية، اعتمدت منهج المسح الاجتماعي بواسطة العينة، واعتمدت (استمارة الاستبيان) بوصفها أداة أساسية في عملية جمع البيانات، وذلك بعد مرورها بمراحل عدة لأجل التحقق من ثباتها ومصداقيتها، ومن أهم النتائج التي توصلنا اليها ان اكثر من نصف العينة يشعرن بأن علاقتهن غير متوافقة مع الازواج، وجاء كأحد اسباب الطلاق العاطفي بينهن وبين ازواجهن متمثلا بانعدام التوافق في المستوى الاجتماعي بين الزوجين ،في حين اكدت اغلب ان المبحوثات على غياب التجديد في الحياة الزوجية الذي كان سبباً في الطلاق العاطفي بين الزوجين، متمثلا ذلك بعدم التعبير بكلمات الحب، والرعاية، والاهتمام من قبل الزوج.
التحولات الرقمية ودورها في التنمية الاقتصادية للشباب
Authors: خضير نور عباس , ساجت خالد حنتوش 
Published: March 2023

تعد الثورة الحاصلة في القرن العشرين المتمثلة بثورة الاتصالات والمعلومات التي شهدها العالم بمثابة نقلة تنموية نوعية لا تقل أهمية ابداً عن الثورة الصناعية، حيث عدت هذه الثورة منعطفا تاريخيا في مسيرة التنمية الاقتصادية في حياة البشرية المعاصرة، حيث اخترقت جميع القطاعات الخدمية والاقتصادية والاجتماعية والسياسية واخذت تغطي الجانب الاقتصادي بشكل كبير مما أعطاها وصف ثورة الاقتصاد الرقمي، ناقش البحث الموسوم (التحولات الرقمية ودورها في التنمية الاقتصادية للشباب دراسة ميدانية في مدينة بغداد) أهمية وطرق وتطبيقات التحول الرقمي في المجتمع العراقي وأهمية اكتشاف العلاقة العضوية بين التحول الرقمي والتنمية الاقتصادية للشباب وأستثمار رأس المال البشري كحلقة وصل بين التحول الرقمي والتنمية الاقتصادية للشباب.
دور بعض العوامل الطبيعية (البنية الجيولوجية، مظاهر السطح، الموارد المائية، التربة) في تحديد مسارات شبكة طرق النقل البرية في قضاء الطارمية
Authors: خضير عماد جدوع , مرضي احمد صباح 
Published: March 2023

تناول البحث تأثير بعض العوامل الطبيعية لا سيما البنية الجيولوجية، مظاهر السطح، الموارد المائية والتربة في تحديد مسارات شبكة طرق النقل البرية في قضاء الطارمية؛ وتوصل البحث الى ان البنية الجيولوجية تشكل عاملاً ايجابياً إذ ان نوع التكوين السطحي يتمثل بالسهل الرسوبي وبالتالي الأمر الذي سهل عملية بناء شبكة الطرق ومد خطوط السكك الحديد.
كما تعد مظاهر السطح احدى العوامل الجغرافية الطبيعية المهمة والتي تؤثر في اختيار المواقع الملائمة التي تمتد اليها شبكات الطرق؛ وان منطقة الدراسة تقع ضمن اقليم السهل الرسوبي التي تميزت بالانبساط إذ يكاد يخلو من تباين اشكال سطح الأمر الذي أدى الى سهولة مد شبكة طرق النقل البرية في قضاء الطارمية.
اما بالنسبة للموارد المائية لها دور كبير ومؤثر في تحديد شبكات طرق النقل ورسم مساراتها، وتؤثر الموارد المائية بدورها في تحديد مسارات الطرق بشكل إيجابي من خلال مد الطرق التي اقترنت مع طبيعة امتداد الموارد المائية.
اما التربة فقد تمثل تأثيرها في مد شبكة طرق النقل البرية؛ اذ ان ساعدت تربة كتوف الأنهار على انتشار السكان بكثافة جيدة؛ كما انها ساهمت في انتشار الزراعة والفعاليات الأخرى، وامتداد شبكة طرق النقل البرية كانت موازية لتربة كتوف الأنهار ومثال ذلك الطريق الرئيسي الذي يربط مركز قضاء الطارمية بناحية العبايجي، اما تربة احواض الأنهار فإن تأثيرها سلبي من خلال صعوبة النقل لا سيما في أيام الامطار خلال فصلي الشتاء والربيع إذ تلتصق الاطيان (الاوحال) بإطارات السيارات الأمر الذي يتسبب بحدوث مشاكل وحوادث، وعند سقوط الامطار مرة أخرى على الترب المنقولة بواسطة إطارات السيارات يؤدي ذلك الى تدمير بُنية الطريق وتخريبها.
Evaluation of the outcome of myringoplasty in active versus inactive chronic otitis media without cholesteatoma
Authors: Ridha Firdaws F. , Khefi Raed A. , Alwan Muhanned M. 
Published: March 2023

Background: Myringoplasty is a procedure used to seal(reconstruct) a perforated tympanic membrane using a graft material by underlay or overlay techniques . Temporalis fascia is the commonly used graft material.Aim of study: to evaluate the difference in outcome of myringoplasty in cases of active and inactive chronic otitis media without cholesteatoma.Patients and Methods: a prospective study of 54 cases of myringoplasty in adult age group whom age ranges from (20-40 years) and the duration of the disease ranges from (6-24 months). All patients were complaining of chronic otitis media without cholesteatoma assessed clinically, audiologically and radiologically, all cases operated under general anesthesia and temporalis fascia grafting (underlay technique) via post-auricular incision.Results: twenty six (48.2%) patients had an active chronic otitis media without cholesteatoma while the remaining twenty eight (51.8%) patients had an inactive chronic otitis media without cholesteatoma those with an active disease 21 (80.8%) cases have successful closure of the perforation while in those 28 cases with an inactive disease 24 (85.7%) cases have successful closure of the perforation. Factors of gender, age, side of the perforation, duration of the perforation, and the pre-operative management for the active ears had no significant effect on the outcome of myringoplasty, P values = 0.5, 0.1, 0.9, 0.5, 0.6, 0.6 and 0.7 respectively which are > 0.05. The overall percentage of success of grafting was 83.3% and the failure of grafting was 16.7%.Conclusion:- The activity of the middle ear (infection) has little impact on the success rate of closure of tympanic membrane perforation.
A HYBRID FUZZY-MONTE CARLO SIMULATION APPROACH FOR ECONOMICAL ASSESSMENT OF THE IMPACT OF ERP TECHNOLOGY
Authors: Hamundu Ferdinand Murni , Wibowo Satriyo , Budiarto Rahmat 
Published: March 2023

Enterprise Resource Planning (ERP) is believed to be able to support the effectiveness of a business process of either goods or services through reliability of information flow among the different function areas of multiple business units. Many managers know this benefit, but they are still vacillating to decide to invest an ERP in their structure. This vacillation comes from considerations of budget and uncertainty or risk of economic constraints. Therefore, taking into account the ERP contribution or impact both of tangible and intangible values through cost and benefit analysis is essential for the success of this project. In this paper, we will reveal how the factor of cost and benefit in an economical assessment can be applied to the ERP investment plan. The expected increase of market share due to customer satisfaction is determined in expressions of information cycle time and quality between customers and suppliers by using a Fuzzy rule-based system. Furthermore, a Monte-Carlo simulation method is used to consider such uncertainties in calculating the expected net present value (NPV).