bluuebunny/crossref_metadata_2025_split huggingface dataset:
The price of quality: Scholarly publishing business is the primary predictor of citation-based indicators of journal performance in ecology and evolutionary biology
Authors: Ruggiero Adriana 
Published: April 2023

Abstract
Citation-based indicators of journals’ performance are often assumed to offer an objective, albeit indirect, way of measuring research quality. However, recent concerns about their applicability for research evaluation suggested these indicators could depend on historical and socioeconomic factors associated with scholarly publishing tradition and business, respectively. The present study addressed this issue quantitatively, using data on h-index and Scimago Journal Rank (SJR) for 566 journals within the fields of ecology and evolutionary biology, and applying Partial Least Squared Structural Equation Modelling. The Tradition Model accounted for &lt;50% of the variation in h-index and SJR, showing that journals’ performance increased with an increase in articles’ international collaboration, and decreased for journals published by non-profit organizations. The Business Model accounted for &gt;60% of the variation in h-index and SJR, showing that journals’ performance increased in association with the global50 ranking of publishers and high article processing charges. Countries recognized as world science centres, the use of English, the journal’s, and publisher’s year of origin, and the increase in science investment and scientific production promoted by the richest economies worldwide had no impact on journal performance. Results suggest that the h-index for journals and the SJR reflect multi-dimensional aspects of scholarly publishing, potentially affected by marketing strategies boosted by the biggest commercial publishers. Given the limitations of poor scientific communities in terms of publication costs, uncritical application of these indexes for research evaluation worldwide may reinforce the idea that high quality research is produced only by rich scientific societies.
Presence and activity of nitrogen-fixing bacteria in Scots pine needles in a boreal forest: a nitrogen-addition experiment
Authors: Bizjak Tinkara , Sellstedt Anita , Gratz Regina , Nordin Annika 
Published: April 2023

Abstract
Endophytic nitrogen-fixing bacteria have been detected and isolated from the needles of conifer trees growing in North American boreal forests. Because boreal forests are nutrient-limited, these bacteria could provide an important source of nitrogen for tree species. This study aimed to determine their presence and activity in a Scandinavian boreal forest, using immunodetection of nitrogenase enzyme subunits and acetylene-reduction assays of native Scots pine (Pinus sylvestris L.) needles. The presence and rate of nitrogen fixation by endophytic bacteria were compared between control plots and fertilized plots in a nitrogen-addition experiment. In contrast to the expectation that nitrogen-fixation rates would decline in fertilized plots, as seen, for instance, with nitrogen-fixing bacteria associated with bryophytes, there was no difference in the presence or activity of nitrogen-fixing bacteria between the two treatments. The extrapolated calculated rate of nitrogen fixation relevant for the forest stand was 20 g N ha−1 year−1, which is rather low compared with Scots pine annual nitrogen use but could be important for the nitrogen-poor forest in the long term. In addition, of 13 colonies of potential nitrogen-fixing bacteria isolated from the needles on nitrogen-free media, 10 showed in vitro nitrogen fixation. In summary, 16S rRNA sequencing identified the species as belonging to the genera Bacillus, Variovorax, Novosphingobium, Sphingomonas, Microbacterium and Priestia, which was confirmed by Illumina whole-genome sequencing. Our results confirm the presence of endophytic nitrogen-fixing bacteria in Scots pine needles and suggest that they could be important for the long-term nitrogen budget of the Scandinavian boreal forest.
Fire intensity impacts on physiological performance and mortality in Pinus monticola and Pseudotsuga menziesii saplings: a dose–response analysis
Authors: Sparks Aaron M , Blanco Alexander S , Wilson David R , Schwilk Dylan W , Johnson Daniel M , Adams Henry D , Bowman David M J S , Hardman Douglas D , Smith Alistair M S 
Published: April 2023

Abstract
Fire is a major cause of tree injury and mortality worldwide, yet our current understanding of fire effects is largely based on ocular estimates of stem charring and foliage discoloration, which are error prone and provide little information on underlying tree function. Accurate quantification of physiological performance is a research and forest management need, given that declining performance could help identify mechanisms of—and serve as an early warning sign for—mortality. Many previous efforts have been hampered by the inability to quantify the heat flux that a tree experiences during a fire, given its highly variable nature in space and time. In this study, we used a dose–response approach to elucidate fire impacts by subjecting Pinus monticola var. minima Lemmon and Pseudotsuga menziesii (Mirb.) Franco var. glauca (Beissn.) Franco saplings to surface fires of varying intensity doses and measuring short-term post-fire physiological performance in photosynthetic rate and chlorophyll fluorescence. We also evaluated the ability of spectral reflectance indices to quantify change in physiological performance at the individual tree crown and stand scales. Although physiological performance in both P. monticola and P. menziesii declined with increasing fire intensity, P. monticola maintained a greater photosynthetic rate and higher chlorophyll fluorescence at higher doses, for longer after the fire. Pinus monticola also had complete survival at lower fire intensity doses, whereas P. menziesii had some mortality at all doses, implying higher fire resistance for P. monticola at this life stage. Generally, individual-scale spectral indices were more accurate at quantifying physiological performance than those acquired at the stand-scale. The Photochemical Reflectance Index outperformed other indices at quantifying photosynthesis and chlorophyll fluorescence, highlighting its potential use to quantify crown scale physiological performance. Spectral indices that incorporated near-infrared and shortwave infrared reflectance, such as the Normalized Burn Ratio, were accurate at characterizing stand-scale mortality. The results from this study were included in a conifer cross-comparison using physiology and mortality data from other dose–response studies. The comparison highlights the close evolutionary relationship between fire and species within the Pinus genus, assessed to date, given the high survivorship of Pinus species at lower fire intensities versus other conifers.
Yes‐associated protein promotes the proliferation and differentiation of liver progenitor cells during liver fibrosis
Authors: Shen Zhenyang , Dai Weiming , Guo Yuecheng , Wang Junjun , Shen Bo , Li Binghang , Lu Lungen , Cai Xiaobo 
Published: April 2023

AbstractLiver fibrosis is closely related to the proliferation and differentiation of liver progenitor cells (LPCs). Yes‐associated protein (YAP) is a key effector molecule of the Hippo signaling pathway and plays an important role in regulating cell proliferation and liver homeostasis. However, its role in LPCs proliferation and differentiation during liver fibrosis are not well understood. Using immunohistochemistry, immunofluorescence staining, quantitative PCR and Western blotting, we discovered that LPCs expansion and enhanced YAP expression in LPCs in either choline‐deficient, ethionine‐supplemented (CDE) diet or 3,5‐diethoxycarbonyl‐1,4‐dihydrocollidine (DDC) diet‐induced fibrotic mice, as well as in patients with liver fibrosis. By injecting adeno‐associated virus vectors under the transcriptional control of Lgr5 promoter, we found that targeted knockdown of YAP in LPCs attenuated the CDE/DDC diet‐induced ductular reaction and liver fibrosis. Using EdU incorporation and Cell Counting Kit‐8 assays, we demonstrated that YAP can modulate LPCs proliferation. Importantly, spleen transplantation of YAP‐overexpressing LPCs improved their ability to differentiate into hepatocytes and alleviated carbon tetrachloride‐induced liver fibrosis. Collectively, our findings indicate that LPCs expansion and differentiation during liver fibrosis could be modulated by YAP, further suggesting the possibility of manipulating YAP expression in LPCs as a potential treatment for chronic liver diseases.
Implantable loop recorder detection for atrial fibrillation to prevent stroke in high-risk patients
Authors: Cadet Myriam Jean , Ronca Kathleen 
Published: April 2023

Abstract:
Implantable loop recorders (ILRs) are cardiac-monitoring devices that detect dangerous dysrhythmias, such as atrial fibrillation (AF). This article discusses whether ILRs can prevent strokes in high-risk patients by detecting AF.
Voices of women veterans
Authors: Capitulo Kathleen , Olender Lynda 
Published: April 2023

Abstract

Purpose:
To explore women veterans' experiences by writing short stories of their lives as part of a program, My Life, My Story (MLMS), and qualitatively analyzing the aggregate stories to identify themes, risks, and opportunities for changes in care.

Methods:
We interviewed women veterans receiving care and/or working at the James J. Peters VA Medical Center in the Bronx, N.Y. Women researchers experienced in the narrative storytelling model, MLMS, wrote participants' short stories. Twenty-two stories were written, aggregated, coded, and reviewed multiple times until saturation; no new themes emerged. The researchers established trustworthiness, consistency, and credibility.

Results:
Themes from data from the stories of women veterans included reasons for choosing a military career, military and postmilitary experiences, psychological and military sexual trauma (MST), access to mental health care and support, antiwomen/misogynistic perceptions, relationships, life after military service, experiences with VA care and services, and future goals.

Conclusion:
Women veterans have very different military and postmilitary experiences from men. Given the increasing number of women veterans who experience homelessness, MST, and posttraumatic stress disorder, providers, the healthcare community, and the public need to hear the voices of women veterans, learn about their military experiences, and redesign women veterans' healthcare to better meet their unique needs by improving supportive mental and physical health care services.
An overview of penicillin allergies for nurses
Authors: Wrynn Alexander F. 
Published: April 2023

Abstract:
Antibiotics are frequently reported as allergies by patients, particularly antibiotics from the penicillin family. Most of these reported allergies are benign, and the consequences of alternative therapies can be significant. This article provides background information on penicillin allergies and serves as a guide to penicillin allergy management.
Reprinted with permission from Wrynn, A.F. An overview of penicillin allergies for nurses. Nurse Pract 2022; 47(9): 30–36. Copyright Wolters Kluwer. All rights reserved.
Childhood obesity and hypertension in pregnancy: a two-sample Mendelian randomization analysis
Authors: Hu Bing , He Xin , Li Fei , Sun Yanxiang , Sun Jie , Feng Li 
Published: April 2023

Background:
The causal relationship between childhood obesity and hypertension in pregnancy remains unclear. To examine the causal association between childhood obesity and hypertension in pregnancy, two-sample Mendelian randomization analysis was applied.

Methods:
Single-nucleotide polymorphisms (SNPs) associated with childhood obesity were obtained from a published genome-wide association study (GWAS) of 13 848 European individuals. Summary-level data for hypertension in pregnancy were obtained from the FinnGen consortium (11534 cases and 162212 controls). Inverse-variance weighted analysis, weighted-median analysis, and Mendelian randomization-Egger regression were conducted in this Mendelian randomization analysis. Sensitivity analyses were conducted to confirm the accuracy and robustness of our results.

Results:
Genetically determined childhood obesity significantly affects hypertension in pregnancy by IVW [odds ratio (OR) = 1.161, 95% confidence interval (CI) 1.086–1.039; P = 9.92 × 10−6] and weighted median (OR = 1.123, 95% CI 1.038–1.214; P = 0.004). These results were validated by multiple sensitivity analyses.

Conclusion:
A causal effect between genetically predicted childhood obesity and the risk of hypertension in pregnancy was identified. The prevention of hypertension in pregnancy should be promoted in populations with childhood obesity.
The Effectiveness of a Motivational Interviewing Intervention on Mutuality Between Patients With Heart Failure and Their Caregivers
Authors: Pucciarelli Gianluca , Occhino Giuseppe , Locatelli Giulia , Baricchi Marina , Ausili Davide , Rebora Paola , Cammarano Andrea , Alvaro Rosaria , Vellone Ercole 
Published: April 2023

Background
Mutuality, defined as “the positive quality of the relationship between a caregiver and a care receiver”, was found to be associated with self-care and caregiver contribution to self-care in heart failure (HF). However, no studies were conducted to evaluate whether motivational interviewing (MI) can improve mutuality in patients with HF and caregivers.

Objectives
The aim of this study was to evaluate the effectiveness of MI on mutuality in HF patient–caregiver dyads.

Methods
This is a secondary outcome analysis of the MOTIVATE-HF randomized controlled trial, the primary aim of which was to evaluate the effect of MI on improving self-care in patients with HF. Participants were randomized into 3 arms: (1) MI for patients only, (2) MI for both patients and caregivers, and (3) standard care. To assess the HF patients' and caregivers' mutuality, the Mutuality Scale was used in its patient and caregiver versions.

Results
Patients with HF had a median age of 74 years, and there were more men (58%). Most patients were retired (76.2%). Caregivers had a median age of 55 years and were mostly women (75.5%). Most patients were in New York Heart Association class II (61.9%) and had an ischemic HF etiology (33.6%). The motivational interviews did not show any impact on changes in the patient and caregiver mutuality during the follow-up time (3, 6, 9, and 12 months from baseline). The condition of living together between the patient and the caregiver was significantly associated with better mutuality between the patient and the caregiver.

Conclusions
Motivational interviewing performed by nurses was not effective in improving mutuality in patients with HF and caregivers, but the target variable of the intervention was patient self-care. Stronger effects of MI on mutuality were observed in patients with HF and caregivers who live together. Future studies should target mutuality to see whether MI is really effective.
Illness Perceptions and Health-Related Quality of Life in Women and Men With Atrial Fibrillation
Authors: Holmlund Lena , Hörnsten Carl , Valham Fredrik , Olsson Karin , Hörnsten Åsa , Ängerud Karin Hellström 
Published: April 2023

Background
Health-related quality of life (HRQoL) is worse in patients with atrial fibrillation (AF) compared with other populations. Factors affecting HRQoL in patients with AF are not fully clarified. Illness perceptions are important determinants of disease management and may affect HRQoL.

Objective
The aims of this study were to describe illness perceptions and HRQoL in women and men with AF and to explore the relationship between illness perceptions and HRQoL in patients with AF.

Methods
This cross-sectional study included 167 patients with AF. Patients completed the Revised Illness Perception Questionnaire and HRQoL questionnaires: Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias, the three-level version of the EuroQol 5-dimensional questionnaire, and EuroQol visual analog scale. Subscales of the Revised Illness Perception Questionnaire significant in correlation analysis with the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias HRQoL total scale were included in a multiple linear regression model.

Results
Mean age was 68.7 ± 10.4 years, and 31.1% were women. Women reported lower personal control (P = .039) and worse HRQoL measured with the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmias physical subscale (P = .047) and the EuroQol visual analog scale (P = .044) compared with men. Illness identity (P < .001), consequences (P = .031), emotional representation (P = .014), and timeline cyclical (P = .022) were related to and adversely affected HRQoL.

Conclusions
This study found a relationship between illness perceptions and HRQoL. Some subscales of illness perceptions negatively affected HRQoL in patients with AF, which indicates that efforts to change illness perceptions may be helpful in improving HRQoL. Patients should be given the opportunity to talk about the disease, their symptoms, their emotions, and the consequences of the disease to enable increased HRQoL. A challenge for healthcare will be to design support for each patient based on his/her illness perceptions.
Type of Health Care Experience Impact on PA Education Association End of Rotation Exam Scores
Authors: Lolar Sara , Nandwana Bindiya , Maher Sara F. 
Published: April 2023

Introduction
The physician assistant (PA) profession is based on previous healthcare experience (HCE), yet few studies have examined the influence of HCE on outcomes. This exploratory study examined possible differences between type of HCE and End of Rotation scores as a surrogate for clinical acumen and medical knowledge.

Methods
Participants included consecutive classes of PA students (2017-2020) from a single public institution (N = 196). Self-reported HCE was used to classify students into HCE groups: group 1, lower decision-making professions; and group 2, higher decision-making professions.

Results
Group 1 (n = 124) and group 2 (n = 72) had no significant difference in the 7 individual End of Rotation exam scores and HCE (p =.163 to .907). A correlation was found between average End of Rotation exam score and PANCE scores (r =.80, p ≤ .001).

Discussion
The impact of HCE during the clinical year of education and its influence on noncognitive attributes, such as communication skills and professionalism, is not known. HCE might have a role in hard to measure noncognitive, nonquantifiable qualities.
Risk factors for delayed recovery in postanesthesia care unit after surgery: a large and retrospective cohort study
Authors: Zhang Qingtong , Xu Feng , Xuan Dongsheng , Huang Li , Shi Min , Yue Zichuan , Luo Dongxue , Duan Manlin 
Published: April 2023

Background:
Delayed recovery in the postanesthesia care unit (PACU) after surgery, as a severe occurrence, influences enhanced recovery after surgery. The data from the observational clinical study is a paucity.

Materials and Methods:
This large, retrospective, and observational cohort study initially included 44 767 patients. The primary outcome was risk factors for delayed recovery in PACU. A generalized linear model and nomogram were employed to identify risk factors. Discrimination and calibration were used to evaluate the performance of the nomogram via internal and external validation.

Results:
Of 38 796 patients, 21 302 (54.91%) were women. The delayed recovery aggregate rate was 1.38% [95% CI, (1.27, 1.50%)]. In a generalized linear model, risk factors for delayed recovery were old age [RR, 1.04, 95% CI, (1.03,1.05), P<0.001], neurosurgery [RR, 2.75, 95% CI, (1.60, 4.72), P<0.001], using antibiotics during surgery [RR, 1.30, 95% CI, (1.02, 1.66), P=0.036], long anesthesia duration [RR, 1.0025, 95% CI, (1.0013, 1.0038), P<0.001], ASA grade of III [RR, 1.98, 95% CI, (1.38, 2.83), P<0.001], and postoperative analgesia [RR, 1.41, 95% CI, (1.10, 1.80), P=0.006]. In the nomogram, old age and neurosurgery had high scores in the model and contributed significantly to the increased probability of delayed recovery. The area under the curve value of the nomogram was 0.77. The discrimination and calibration of the nomogram estimated by internal and external validation were generally satisfactory.

Conclusion:
This study demonstrates that delayed recovery in PACU after surgery was associated with old age, neurosurgery, long anesthesia duration, an ASA grade of III, using antibiotics during surgery, and postoperative analgesia. These findings provide predictors of delayed recovery in PACU, especially neurosurgeries and old age.
Long-term treatment outcome of patients with complete bilateral cleft lip and palate: a retrospective cohort study
Authors: Hattori Yoshitsugu , Pai Betty C.-J. , Saito Takafumi , Chou Pang-Yun , Lu Ting-Chen , Chang Chun-Shin , Chen Yu-Ray , Lo Lun-Jou 
Published: April 2023

Background:
Patients with cleft lip and palate have functional and esthetic impairment and typically require multiple interventions in their life. Long-term evaluation following a treatment protocol, especially for patients with complete bilateral cleft lip and palate (BCLP), is important but was rarely reported in the literature.

Patients and methods:
A retrospective review was conducted on all patients with complete BCLP born between 1995 and 2002 and treated at our center. Inclusion criteria were having adequate medical records and receiving continuous multidisciplinary team care at least until 20 years of age. Exclusion criteria were lack of regular follow-up and congenital syndromic abnormalities. The medical records and photos were reviewed, and facial bone development was evaluated using cephalometric analysis.

Results:
A total of 122 patients were included, with a mean age of 22.1 years at the final evaluation in this study. Primary one-stage cheiloplasty was performed in 91.0% of the patients, and 9.0% underwent two-stage repair with an initial adhesion cheiloplasty. All patients underwent two-flap palatoplasty at an average of 12.3 months. Surgical intervention for velopharyngeal insufficiency was required in 59.0% of patients. Revisional lip/nose surgery was performed in 31.1% during growing age and in 64.8% after skeletal maturity. Orthognathic surgery was applied in 60.7% of patients with retruded midface, of which 97.3% underwent two-jaw surgery. The average number of operations to complete the treatment was 5.9 per patient.

Conclusion:
Patients with complete BCLP remain the most challenging group to treat among the cleft. This review revealed certain suboptimal results, and modifications have been made to the treatment protocol. Longitudinal follow-up and periodic assessment help to establish an ideal therapeutic strategy and improve overall cleft care.