bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public perception of the appropriateness of COVID-19 management strategies and level of disturbances in daily activities: A focus on educational level
Authors: Ju Yeong Jun , Kim Woorim , Lee Soon Young 
Published: June 2023

Background
This study investigated the association between public perception of the appropriateness of management strategies implemented during the COVID-19 pandemic and the level of disturbances in daily activities reported by the general population.

Methods
This cross-sectional study used Korea Community Health Survey conducted from August to November 2020. Public perception of COVID-19 management strategies included those implemented by the government (central, city or provincial, and administrative districts), the mass media, regional medical institutions, and neighbors. The subjective level of disturbances in daily activities was measured using a 0–100 numeric rating scale developed by Korea Disease Control and Prevention Agency. Multivariable linear regression analysis was used. A subgroup analysis was conducted based on education level.

Results
The present study analyzed 211,353 participants. Compared to individuals who perceived that the management strategies implemented during the pandemic was ‘highly appropriate,’ those who reported ‘mediocre appropriateness’ (β: -1.96, p-value: <0.001) or ‘low appropriateness’ (β: -3.60, p-value: 0.010) reported higher levels of subjective disturbances. The appropriateness of measures implemented by the mass media was associated with levels of subjective disturbances felt by individuals of lower education with statistical significance, whereas that applied by the mass media and the government were important in those with higher education.

Conclusions
The findings suggest the importance of public perception of management strategies when implementing containment policies and minimizing its disturbances on daily lives is essential.
Isolasi dan Karakterisasi Amilase Termostabildari Geobacillus dYtae-14
Authors: Aminin Agustin L.N. , Milarsih Yulia , Mulyani Nies Suci 
Published: June 2023

Enzim amilase termostabil merupakan salah satu enzim yang sangat potensial bagi industri, terutama industri makanan dan farmasi. Enzim termostabil memiliki beberapa keuntungan seperti reaksi berlangsung lebih cepat, menurunkan viskositas dan mencegah kontaminasi karena produksi berlangsung pada suhu tinggi. Penelitian ini mengeksplorasi potensi amilase termostabil dari isolat lokal Geobacillus dYTae-14 yang tumbuh optimum pada suhu 55oC. Aktivitas spesifik amilase ditentukan berdasarkan produk glukosa yang diukur dengan metode DNS dan kadar protein ditentukan dengan metode Lowry. Tahapan penelitian ini meliputi pembuatan kurva pertumbuhan, isolasi enzim amilase termostabil, pemurnian parsial enzim, dialisis, penentuan aktifitas spesifik tiap fraksi, penentuan kandungan protein, penentuan temperatur dan pH optimum. Amilase termostabil dari Geobacillus dYTae-14 berhasil diisolasi dan menunjukkan aktivitas spesifik tertinggi pada fraksi kejenuhan ammonium sulfat 20-40%, sebesar 934,356 unit/mg protein. Temperatur optimum amilase termostabil dicapai pada 85oC dan pH optimum di pH 8; dengan aktivitas spesifik sebesar 2143,538 unit/mg protein.
Ett utile dulci för ungdom
Authors: Kärrholm Sara 
Published: June 2023

An Utile Dulci for Youth: Ungdomens bibliotek as Book Series and Publishing Project
The Swedish publishing house Svensk läraretidnings förlag published the extensive book series Barnbiblioteket Saga (the Children’s Library Saga) between 1899 and 1970. In this article, the publisher’s less extensive book series Ungdomens bibliotek (the Library of Youth) is analysed as an example of the marketing techniques that the publishing house used to reach different target groups. The article investigates how the publishing house used their smaller book series as a way to diversify and increase visibility for their books at a time when the main series Barnbiblioteket Saga was growing into a vast phenomenon that was becoming increasingly difficult to overview. This is investigated through an analysis of the book series’ paratexts, drawing on different theories from the field of publishing studies about the marketing of literature. The article focuses on marketing – through the book covers as well as material inside the books – and advertising. The study provides an explanation of how the publishing house used their marketing of Ungdomens bibliotek to strengthen their brand and expand their business from the 1920s through the 1940s. They accomplished this by developing strategies for curation: they curated a book series targeted for a more specific audience segment than the larger Barnbiblioteket Saga, while also emphasising the qualities that were associated with all their work: pedagogy, accessibility, richness (in subjects and variety), and formation.
Estetiken i praktiken
Authors: Lyngfelt Anna , Björklund Camilla 
Published: June 2023

Aesthetics in Practice: About the Relationship Between Aesthetics and Pedagogy When Reading Lisen Adbåge’s Samtidigt som
The purpose of this article is to investigate the relationship between aesthetics and pedagogy by focusing on a picturebook’s aesthetic design and students’ understanding of time as abstraction. The survey uses Lisen Adbåge’s picturebook Samtidigt som (At the Same Time As, 2017), which was read and discussed in three Swedish preschool classes. In the study, the book’s artistic forms of expression are linked to students’ statements about what ”at the same time as” means. The research questions are: a) How does time appear as a phenomenon through the book’s artistic forms of expression? b) What do the children focus on in doublespreads that arouse their interest when they reason about what ”at the same time” means? and c) Is it possible to discern what specifically triggers thoughts about time through the aesthetic design of the book? To answer the research questions, theory for picturebook analysis (Laukka) and play research (Pramling et al.) is used, as well as conversation analysis (Sidnell and Stivers). Through the children’s comments when reading the book aloud to them, it turns out that seven of the 13 doublespreads in the book attract the children’s interest more than the others, and these are the doublespreads that contain an interplay between what happens (”as is”) and may happen (”as if”). Play research’s use of ”as is” and ”as if” is therefore proposed as a starting point for understanding children’s interpretation of a picturebook, that is, as thought play. Also, this implies that aesthetic means are important for developing an understanding of abstractions such as time.
A numerical study on thin film flow and heat transfer enhancement for copper nanoparticles dispersed in ethylene glycol
Authors: Hayat Umer , Ali Ramzan , Shaiq Shakil , Shahzad Azeem 
Published: June 2023

Abstract
The current study examines thin film flow and heat transfer phenomena with some additional effects such as magnetohydrodynamic, viscous dissipation, and slip condition over unsteady radially stretching surfaces for various shapes of copper

(
Cu
)

\left({\rm{Cu}})

nanoparticles dispersed in ethylene glycol

(
EG
)

\left({\rm{EG}})

. The effective thermal conductivity of a nanofluid made of Cu nanometer-sized particles distributed in

EG

{\rm{EG}}

is significantly higher than that of pure EG. Partial differential equations are transformed into ordinary differential equations using the proper transformations. An effective convergent technique (i.e., BVP4C) is used to compute the solutions of nonlinear systems. MATLAB software is used to perform the calculations. The effect of numerous emerging physical characteristics on temperature and velocity, such as unsteadiness parameter

(
S
)

\hspace{ 1em}\left(S)

, slip parameter

(
K
)

\left(K)

, Hartmann number

(
M
)

\left(M)

, solid volume fraction

(

ϕ

)

(\phi )

, and Eckert number

(
EC
)

\left({\rm{EC}})

is investigated and illustrated graphically. The physical quantities, such as the skin friction coefficient and the Nusselt number, are calculated, described, and displayed in tabular form. It is observed that blade-shaped Cu nanoparticles had the lowest surface drag, highest heat transfer rate, and minimum film thickness compared to the brick and cylinder-shaped nanoparticles. According to our detailed investigation blade-shaped

Cu

{\rm{Cu}}

nanoparticle is the most suited solution for manufacturing unsteady radially stretching modules.
Research and analysis on low-velocity impact of composite materials
Authors: Qiu Ju 
Published: June 2023

Abstract
In this article, the concept of low-velocity impact resistance in composite materials is presented. Three existing expressions (e.g., bilinear, parabola, and exponential) that show the relationship between the dent depth and impact energy of composite laminates subjected to low-velocity impact are presented. Because of some flaws in these expressions, new supposed functions between impact energy and impact dent have been established. By means of existing ASTM D 7136 tests and simulation analysis, the new expressions are verified, and the nature of dent formation in composite materials is well explained. The conclusion is reflected in the ending part.
Characterization of Fatigue Damage Properties of Fine Aggregate Matrix and Hot Mix Asphalt
Authors: Liu Hongfu , Ge Wenwen , Liang Guoxi , Yang Xinyu , Chen Liyin , Jin Dongzhao , Chu Chenfeng , Gong Xiangbin , Yu Huanan , Lv Songtao 
Published: June 2023

Abstract
It is still a challenge to evaluate the fatigue damage property of hot mix asphalt (HMA) with low workload, low cost, and high efficiency. This study aims to better evaluate the fatigue damage properties of asphalt mixtures by testing and characterizing the fatigue damage behavior of fine aggregate matrix (FAM) and HMA. Three varieties of HMA and corresponding FAM were created using neat asphalt, styrene-butadiene-styrene modified asphalt, and high-modulus modified asphalt. The dynamic modulus of the three types of HMA and FAM were tested using the standard performance tester. The materials testing system is used to conduct a direct tensile fatigue test on the three types of HMA and FAM. The fatigue performance of HMA and FAM was investigated using the simplified viscoelastic continuum damage model. The damage characteristic curves of FAM and HMA, as well as the master curve of dynamic modulus and phase angle, were assessed. Additionally, the apparent damage capacity and average pseudo stiffness reduction value (DR) were used to evaluate the fatigue characteristic between FAM and HMA. The findings show that: (1) for FAM and HMA prepared by the same asphalt binder, there is a high degree of shape and change similarity between the master curves of dynamic modulus and phase angle. (2) Based on the Tukey multiple comparison test and two-way analysis of variance, the fatigue performance of HMA and FAM were evaluated by DR and had higher discrimination ability and sensitivity. (3) There is a significant correlation between HMA and the FAM fatigue index DR. The evolution of FAM’s fatigue damage is similar to that of HMA’s. It is feasible to test the dynamic and fatigue performance of the FAM using the experimental methods in this article.
Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in mice
Authors: Yu Yaqin , Liu Yuanyuan , Sui Xuesong , Sui Yanyu , Wang Zhe , Mendelson Carole R , Gao Lu 
Published: June 2023

AbstractFetal development and parturition are precisely regulated processes that involve continuous crosstalk between the mother and the fetus. Our previous discovery that wild‐type mice carrying steroid receptor coactivator (Src)‐1 and Src‐2 double‐deficient fetuses exhibit impaired lung development and delayed labor, which indicates that the signals for parturition emanate from the fetus. In this study, we perform RNA sequencing and targeted metabolomics analyses of the lungs from fetal Src‐1/‐2 double‐knockout mice and find that expression of arginase 1 (Arg1) is significantly decreased, accompanied by increased levels of the Arg1 substrate L‐arginine. Knockdown of Arg1 in the lungs of fetal mice induces apoptosis of epithelial cells and dramatically delays initiation of labor. Moreover, treatment of human myometrial smooth muscle cells with L‐arginine significantly inhibits spontaneous contractions by attenuating activation of NF‐κB and downregulating expression of contraction‐associated protein genes. Transcription factors GR and C/EBPβ increase transcription of Arg1 in an Src‐1/Src‐2‐dependent manner. These findings provide new evidence that fetus‐derived factors may play dual roles in coordinating fetal lung development and the initiation of labor.
Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis
Authors: Mani Srinivasan , Hazra Snehashis , Hagan Joseph , Sisson Amy , Nair Jayasree , Pammi Mohan 
Published: June 2023

CONTEXT
Necrotizing enterocolitis (NEC) is a devastating intestinal disease affecting preterm infants. Studies implicate viral infections in etiopathogenesis.

OBJECTIVE
To summarize the association of viral infections with NEC by systematic review and meta-analysis.

DATA SOURCES
We searched Ovid-Medline, Embase, Web of Science, and Cochrane databases in November 2022.

STUDY SELECTION
We included observational studies that examined the association between viral infections and NEC in newborn infants.

DATA EXTRACTION
We extracted data regarding the methodology, participant characteristics, and outcome measures.

RESULTS
We included 29 and 24 studies in the qualitative review and meta-analysis, respectively. The meta-analysis demonstrated a significant association between viral infections and NEC (odds ratio [OR], 3.81, 95% confidence interval: 1.99–7.30, 24 studies). The association remained significant after excluding the outliers (OR, 2.89 [1.56–5.36], 22 studies) and studies with poor methodology (OR, 3.33 [1.73–6.43], 22 studies). In subgroup analysis based on participants' birth weight, studies including very low birth weight infants only (OR, 3.62 [1.63–8.03], 8 studies) and non-very low birth weight infants only (OR, 5.28 [1.69–16.54], 6 studies) showed a significant association. In subgroup analysis based on specific viruses, infection with rotavirus (OR, 3.96 [1.12–13.95], 10 studies), cytomegalovirus (OR, 3.50 [1.60–7.65], 5 studies), norovirus (OR, 11.95 [2.05–69.84], 2 studies), and astrovirus (OR, 6.32 [2.49–16.02], 2 studies) was significantly associated with NEC.

LIMITATIONS
Heterogeneity of the included studies.

CONCLUSIONS
Viral infection is associated with an increased risk of NEC in newborn infants. We need methodologically sound prospective studies to assess the effect of preventing or treating viral infections on NEC incidence.
Distribution of regional state aid in Slovakia: A focus on the least developed districts
Authors: Košdy Martina 
Published: June 2023

AbstractThis paper examines the geographical distribution of regional state aid in Slovakia between 2004 and 2021, while focusing on projects realized in the least developed districts. The purpose is to answer the following research question: how much investment support is provided to areas with high rates of long-term unemployment to promote local economic activity? The investigation was conducted using a spatial distribution analysis and descriptive statistical methods. The findings demonstrate that the level of support in less developed districts is below the level of aid directed into more developed regions not only in terms of the number of supported projects, but also regarding the total amount of aid and the number of created jobs. Out of the 20 least developed districts we monitored, only the results for Košice-okolie significantly outperformed the results of the other districts. This article provides possible explanations for these findings and contributes to the literature by providing insights into the practical application of state aid in Slovakia.
APPLICATION OF FUZZY LOGIC IN THE ROBOT CONTROL FOR MECHANICAL PROCESSING
Authors: Khoi Phan Bui 
Published: June 2023

Robot application in mechanical machining is growing day by day because it has many advantages over conventional machines such as high flexibility, large working space, and high repeatability. Many degrees of freedom of motion give robots the ability to perform complex technological operations, but also because of that, methods of controlling robots based on dynamic models have difficulties. Applying fuzzy logic to robot control can partially or completely exclude the calculation of the robot's dynamic model as well as overcome other uncertainties of the whole technological system. The variables and parameters of the fuzzy logic-based controller are modeled in a linguistic form, called linguistic variables, and are defined by the linguistic semantic values. Fuzzy rules are an important basis for the performance of operations defining the control quantities of the controller. Fuzzy rules are constructed by natural human inference and are based on expert intelligence. The main tasks of applying fuzzy logic control include “Fuzzification” to determine fuzzy parameters in the form of fuzzy sets of input-output data; “Fuzzy Rules and Fuzzy Inference Mechanism” to perform fuzzy operations defining control quantities, and finally “Defuzzification” to convert control quantities from linguistic values to physical values for controller operation. There have been many types of research on applying fuzzy logic to control robots in general, but the percentage of fuzzy control research work for mechanical machining robots is still limited.
The article is based on published works on fuzzy control for robots in general and mechanical processing robots to analyze the applicability of fuzzy control for mechanical machining robots. The article provides detailed information on fuzzy controller design, on determining input and output variables, proportional mapping to determine the number of fuzzy sets and the corresponding type of membership function. The construction of fuzzy rule base system and fuzzy inference mechanism is presented, and finally defuzzification. Prospects for the use of methods to perfect and develop fuzzy control systems for mechanical machining robots are also presented. Collectively, the information in this document is intended to guide the implementation of fuzzy logic-based controller designs for application to machining robots, as well as to general robot control.
Chronobiological approach to study the physiological activity of <i>Candida</i> species
Authors: Nikolenko M. V. , Baryshnikova N. V. , Malishevskaya O. I. , Vaseva E. M. 
Published: June 2023

Rythmometric markers can be identified within a day during the study of biological characteristics in order to be used for differential diagnostics of pathogens of different patients’ physical condition. These principles are based on analysis of clinical isolates С. albicans, С. tropicalis and C. krusei allocated from the vaginal microbiota at Candida dysbiosis condition. Control examples were the master samples from the American Type Culture Collection (ATCC). Detailed research was conducted on physiological characteristics through the formation of biofilms by yeast pathogens. Biological activity of Candida sp. biofilming was observed within 2 days with 4 hours interval in winter. Daily cultures were used for the experiment to correspond to their maximum adhesion to the glass surface. It was important to obtain 6 measurements per day with 3-5 times repetition of experiment conditions during the specified timeline. In order to determine the periodicity of the parameters studied, the data was statistically processed by Student’s t-test, using Mann–Whitney criteria and nonparametric method of least square method.It was found out that biofilming activity during 24 hours (р < 0.05) of fungi exists and that all species have many principles in common. It was attested that the main rhythmometric parameters of diagnostic significance are the rhythm period and amplitude-phase stability. It was found that the daily dynamics of C. albicans 24433 biofilm formation from American Type Culture Collection was characterized by an ultradian (about 12-hours) contribution of the rhythm in the morning – 4 A.M and in the evening – 4 P.M. Significant circadian (approx. daily) rhythms of adhesion glass surface activity were revealed in C. non-albicans from American Type Culture Collection. The dynamic of biofilm formation isolates of yeast from female reproductive organs with Candida pathology was characterized by reliable ultradian (about 12-hour) harmonics which biological significance defines resistance to external impact and the ability to adaptively respond to periodic stimuli.To sum up, implementation of the chronobiological approach has opened up new prospects for studying the physiology of Сandida sp., as it enables us to predict the dynamics of microbial states and takes into account the specificity of emergency and long-term adaptation to different environmental factors. The detection of the circadian rhythm of biofilm formation activity of different Candida sp. strains provides the possibility to manage the vitality of the Society of Bacteria and Fungi and predicts its resistance to various antibiotics.
Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine
Authors: Kartseva A. S. , Silkina M. V. , Titareva G. M. , Kombarova T. I. , Mironova R. I. , Firstova V. V. 
Published: June 2023

The vaccine strain F. tularensis 15 NIIEG induces long-lived cell-mediated immunity but exhibits a certain reactogenicity and genetic instability. Progress in development of a vaccine against tularemia has been limited by a lack of information regarding the mechanisms required to protect against this disease. The BALB/c mouse is the most commonly used animal to study tularemia due to its relatively low cost, well-characterized genetics, available immunological tools and mouse infection with virulent F. tularensis recapitulates human disease.CD4+ and CD8+T cells are known to be critical for the formation of protective immunity but the relative roles of memory T cell subpopulations in long lived protection against virulent strains of F. tularensis are not well established. We hypothesized that this immunity depends on central (TCM) and effector memory (TEM) T cells and their functional activity. In this study we have dissected the T cell immune response in BALB/c mice 30, 60 and 90 days after subcutaneous vaccination with 15 NIIEG.Multiparametric flow cytometry were used to characterize in vitro recall responses of splenocytes to F. tularensis antigen. TEM cells were identified as CD3+CD4+CD44+CD62L- and CD3+CD8+CD44+CD62L-, TCM cells as CD3+CD4+CD44+CD62L+ and CD3+CD8+CD44+CD62L+, respectively. The functional activity of memory T cells was assessed by the following parameters: the level of expression of the activation marker CD69 and cytokine-producing activity by staining with the intracellular cytokines IFNg and TNFa.Thus, development of a long-lived vaccine directed against F. tularensis is dependent on identifying not only the correlates of immunity present early after vaccination, but also those that persist in the host after the effector phase has ended. The maintenance of long-term protective immunity initiated by vaccination with F. tularensis strain 15 NIIEG has been shown to require the presence of antigen-specific CD4+ and CD8+ memory T cells producing IFNg and TNFa and expressing the activation marker CD69. A decrease in count and functional activity of CD8+TCM and CD8+TEM was detected in the long term after vaccination. The detected parameters of functional activity of memory T cells can be used as criteria for evaluation of protective immunity against virulent strains of F. tularensis.