bluuebunny/crossref_metadata_2025_split huggingface dataset:
Persistence of triclopyr, dicamba, and picloram in the environment following aerial spraying for control of dense pine invasion
Authors: Rolando Carol A. , Scott Matthew B. , Baillie Brenda R. , Dean Fiona , Todoroki Christine L. , Paul Thomas S. H. 
Published: August 2023

AbstractAerial application of an herbicide mixture of triclopyr, dicamba, picloram, and aminopyralid is used to control dense infestations of exotic conifers, notably lodgepole pine (Pinus contortaDouglas ex Loudon), in New Zealand. The rates of herbicide applied to control these tree weeds has the potential for off-target impacts through persistence in the forest floor, soil, and water. Persistence of three of these herbicides was investigated in cast needles, forest floor (litter, fermented humic layer [LFH]), and soil following their operational aerial application (triclopyr: 18 kg ai ha−1; dicamba: 5 kg ai ha−1; picloram: 2 kg ai ha−1) at three sites across New Zealand (KF, MD, GE) with dense invasions ofP. contorta. Water was collected from a local stream at two sites (KF, MD) in the days/months after spraying. Active ingredients detected across all sites in cast needles, LFH, and mineral soil generally reflected their application rates, with total amounts comprising 81% triclopyr, 14% dicamba, and 5% picloram. Most of the active ingredients were detected in the LFH (59%), a heavy lignin-rich layer of dead needles overlaying the soil. All three herbicides persisted in this layer, at all sites, for up to 2 yr (at study termination). Only triclopyr was detected in mineral soil, where it declined to below detection levels (0.2 mg kg−1) within 1 yr. All three herbicides were detected in stream water on the day of spray application at KF, and during a rainfall event 1 mo later. However, amounts did not exceed New Zealand environmental and drinking water standards, an outcome attributed to a 30-m no-spray buffer zone used at this site. At MD, herbicides were detectable in water up to 4 mo after spraying, with amounts exceeding New Zealand drinking water standards on one occasion, 1 mo after spray application. No spray buffer zones were used at the MD site.
Observations, Experiments, and Arguments for Epistemic Superiority in Scientific Methodology
Authors: Boyd Nora Mills , Matthiessen Dana 
Published: August 2023

AbstractThis article argues against general claims for the epistemic superiority of experiment over observation. It does so by dissociating the benefits traditionally attributed to experiment from physical manipulation. In place of manipulation, we argue that other features of research methods do confer epistemic advantages in comparison to methods in which they are diminished. These features better track the epistemic successes and failures of scientific research, crosscut the observation/experiment distinction, and nevertheless explain why manipulative experiments are successful when they are.
A systematic review of interventions targeting modifiable factors that impact dietary intake in athletes
Authors: Janiczak Amy , Alcock Rebekah , Forsyth Adrienne , Trakman Gina Louise 
Published: August 2023

AbstractAppropriate dietary intake has been found to positively impact athletes’ performance, body composition and recovery from exercise. Strategies to optimise dietary intake often involve targeting one or more of the many factors that are known to influence dietary intake. This review aims to investigate the types and effectiveness of interventions used to impact modifiable factors of dietary intake in athletes. MEDLINE, CINAHL, SPORTDiscus and Web of Science were searched from inception to May 2022 for intervention studies that measured dietary intake with a quantitative tool and explored at least one factor thought to influence the dietary intake of adult athletes. Study quality was assessed using the ADA Quality Criteria Checklist: Primary Research. Twenty-four studies were included. The most common interventions focused on nutrition education (n 10), macronutrient adjustment (n 7) and physical activity (n 5). The three most common factors thought to influence dietary intake addressed were nutrition knowledge (n 12), hunger and appetite (n 8), and body composition (n 4). Significant changes in dietary intake were found in sixteen studies, with nutrition education interventions returning significant results in the largest proportion of studies (n 8). Study quality within this review was mostly average (n 4 < 50 %, n 19 50–80 %, n 1 > 80 %). As studies included were published between 1992 and 2021, interventions and factors explored in older studies may require up-to-date research to investigate possible differences in results due to time-related confounders.
Art diplomacy: Drawing China-Indonesia relations in the early Cold War, 1949–1956
Authors: Li Yiqing 
Published: August 2023

AbstractThe mid-1950s saw the relationship between China and Indonesia evolve from one of mutual hostility to one of fraternity as a trend of détente emerged out of the Geneva (1954) and the Bandung (1955) conferences. This article explores why and how the two newly independent nations applied art diplomacy to reduce their ideological differences and facilitate their commercial and political rapprochements for the sake of Asian solidarity. Through contextualizing a series of art activities between the two nations, especially China’s reproduction of President Sukarno’s private collection of paintings and Chairman Mao Zedong’s gifts of Chinese ink paintings to President Sukarno, this article argues that interactions in the name of art exemplify how China shaped its modern profile as an independent and industrialized power. It will also show how China deviated from its diplomacy of ‘Leaning to One Side’, formulated in the late 1940s, towards the ‘Peaceful United Front’ of the mid-1950s. More broadly, art relations between China and Indonesia reflect intensive cultural exchanges between the newly independent, yet ideologically clashing, nations of the Third World in the postwar period and offer a multifaceted history of the Cold War beyond the binary paradigm of the two superpowers of the United States and the Soviet Union.
Modeling EFL learners’ willingness to communicate: The roles of face-to-face and digital L2 communication anxiety
Authors: Lee Ju Seong , Chiu Ming Ming 
Published: August 2023

AbstractThis study proposes and tests a comprehensive model (with demographics, informal digital learning of English, ideal/ought-to L2 self, L2 enjoyment, and self-perceived communication competence) of face-to-face and digital communication anxiety's relationship to willingness to communicate in a second language (L2 WTC) within in-class, out-of-class, and digital contexts. A structural equation model of survey responses from 1,269 Koreans learning English as a foreign language (746 secondary and 523 university students) showed that in all three settings, students with lower anxiety showed greater L2 WTC. Within in-class and out-of-class contexts, students with higher self-perceived English ability had lower face-to-face anxiety, which in turn yielded higher L2 WTC. In digital settings, students with a higher ideal L2 self (i.e., a more positive evaluation of their ability to attain the ideal L2 self) showed less overall anxiety (comprising face-to-face and digital anxieties), which yielded greater L2 WTC. These results suggest that future studies can test whether interventions to lower anxiety can increase L2 WTC across communication venues.
Does reward processing moderate or mediate the link between childhood adversity and psychopathology: A longitudinal study
Authors: Kasparek Steven W. , Gastón-Panthaki Aria , Hanford Lindsay C. , Lengua Liliana J. , Sheridan Margaret A. , McLaughlin Katie A. 
Published: August 2023

AbstractChildhood adversity is common and associated with elevated risk for transdiagnostic psychopathology. Reward processing has been implicated in the link between adversity and psychopathology, but whether it serves as a mediator or moderator is unclear. This study examined whether alterations in behavioral and neural reward processing function as a mechanism or moderator of psychopathology outcomes following adversity experiences, including threat (i.e., trauma) and deprivation. A longitudinal community sample of 10–15-year-old youths was assessed across two waves (Wave 1: n = 228; Wave 2: n = 206). Wave 1 assessed adverse experiences, psychopathology symptoms, reward processing on a monetary incentive delay task, and resting-state fMRI. At Wave 2, psychopathology symptoms were reassessed. Greater threat experiences were associated with blunted behavioral reward sensitivity, which, in turn, predicted increases in depression symptoms over time and mediated the prospective association between threat and depression symptoms. In contrast, reward sensitivity moderated the association between deprivation experiences and prospective externalizing symptoms such that the positive association of deprivation with increasing externalizing symptoms was absent for children with high levels of reward sensitivity.
Natural Denudation Versus Anthropogenically Accelerated Erosion in Central Brazil: A Confrontation of Time and Space Scales
Authors: Siame Lionel L. , Espíndola Rosa Lucas , Soares Cherem Luis Felipe , Guilherme de Oliveira José , Evrard Olivier , Barhoumi Houda , Leanni Laëtitia , Duvivier Adrien , Blard Pierre‐Henri , Bourlès Didier L. , Team ASTER , Cornu Sophie 
Published: August 2023

AbstractLand degradation resulting from increased continental surface erosion is a worldwide and systemic phenomenon due to unsustainable human activities. Already fragile, the intertropical zone is likely to be further affected by climate change like increased aridity, an aggravating factor of soil erosion and land degradation. A major challenge is thus to provide the necessary knowledge to not only deepen our understanding of the Earth's system and its critical thresholds but also to help achieving sustainability. Understanding the factors that control the properties and processes of the critical zone, and especially what will be its responses to ongoing climate and land use changes, requires multidisciplinary efforts to tackle time scales that are compatible with morphogenesis and soil development as well as environmental disturbances of anthropogenic origin. Due to its prominent ecological importance, the Brazilian Cerrado biome is an ideal natural laboratory were to gauge the consequences of recent and intense agricultural activities on continental surface erosion. We focused on the region of Brasília where our approach allows confronting the temporal scales of long‐lived and stable cosmogenic nuclides with that of short‐lived radioactive isotopes, through a comparison of natural and anthropogenically disturbed land surfaces. Our results indicate that long‐term, background denudation rates are lower than 10 mm Kyr−1 whereas recent erosion rates due to human activities may reach rates at least 160 times higher, exceeding by far the sustainability of the soil resource.
Evaluating Habitat Suitability and Tidal Wetland Restoration Actions With ECOSTRESS
Authors: Gustine Rebecca N. , Nickles Cassandra L. , Lee Christine M. , Crawford Brian A. , Hestir Erin L. , Khanna Shruti 
Published: August 2023

AbstractAs temperatures rise, it is increasingly important to monitor changes in habitat conditions for aquatic species and mitigate emerging stressors. The ECOsystem Spaceborne Thermal Radiometer Experiment on Space Station (ECOSTRESS) instrument provides temperature products at a spatial and temporal scale not previously available. Here, we utilize ECOSTRESS temperature products to assess fluctuations in thermal habitat suitability for an endangered fish species and we also demonstrate the utility of the data set to assess water surface and bulk temperature changes following completion of two tidal wetland restoration efforts in the San Francisco Estuary and Sacramento–San Joaquin River Delta (Bay Delta). During all hours of the day throughout the 2018–2022 study period, key Delta Smelt habitat areas including Honker Bay, West Suisun Bay, and Mid Suisun Bay had greater than 75% of their areas suitable; there were several instances during which less than 25% of the area was thermally suitable generally coinciding with heatwave events. Overall, midday hours are less frequently suitable than morning and evening hours. Early evidence from ECOSTRESS indicates that there may be a decrease in surface water temperature of up to several degrees in tidal restoration areas, but more data is needed to show statistically significant outcomes. The ECOSTRESS record began in summer of 2018, and a longer record is needed to fully capture temperature changes associated with wetland processes and restoration efforts. Future applications of ECOSTRESS products can the capacity to help further understand ecosystem conditions and how restoration efforts affect water temperature, informing decisions that benefit Delta Smelt and other at‐risk aquatic species.
Verifying Methane Inventories and Trends With Atmospheric Methane Data
Authors: Worden John R. , Pandey Sudhanshu , Zhang Yuzhong , Cusworth Daniel H. , Qu Zhen , Bloom A. Anthony , Ma Shuang , Maasakkers Joannes D. , Byrne Brendan , Duren Riley , Crisp David , Gordon Deborah , Jacob Daniel J. 
Published: August 2023

AbstractThe 2015 Paris Climate Agreement and Global Methane Pledge formalized agreement for countries to report and reduce methane emissions to mitigate near‐term climate change. Emission inventories generated through surface activity measurements are reported annually or bi‐annually, and evaluated periodically through a “Global Stocktake.” Emissions inverted from atmospheric data support evaluation of reported inventories, but their systematic use is stifled by spatially variable biases from prior errors combined with limited sensitivity of observations to emissions (also called smoothing error), as‐well‐as poorly characterized information content. Here, we demonstrate a Bayesian, optimal estimation (OE) algorithm for evaluating a state‐of‐the‐art inventory (EDGAR v6.0) using satellite‐based emissions from 2009 to 2018. The OE algorithm quantifies the information content (uncertainty reduction, sectoral attribution, spatial resolution) of the satellite‐based emissions and disentangles the effect of smoothing error when comparing to an inventory. We find robust differences between satellite and EDGAR for total livestock, rice, and coal emissions: 14 ± 9, 12 ± 8, −11 ± 6 Tg CH4/yr respectively. EDGAR and satellite agree that livestock emissions are increasing (0.25–1.3 Tg CH4/yr/yr), primarily in the Indo‐Pakistan region, sub‐tropical Africa, and the Southern Brazilian; East Asia rice emissions are also increasing, highlighting the importance of agriculture on the atmospheric methane growth rate. In contrast, low information content for the waste and fossil emission trends confounds comparison between EDGAR and satellite; increased sampling and spatial resolution of satellite observations are therefore needed to evaluate reported changes to emissions in these sectors.
Net Community Production in the Argentine Basin Estimated From Nitrate Drawdown Using Biogeochemical Argo Floats
Authors: Alkire Matthew B. , Riser Stephen 
Published: August 2023

AbstractNet community production (NCP) was estimated from nitrate profiles measured via biogeochemical Argo floats drifting in the Argentine Basin. Two criteria were tested for defining hydrographic fronts used to separate the study area into five zones: potential density anomaly at 450 m and potential temperature at 100 m. The latter definition was preferred as it minimized overlapping among zones. Float profiles within each zone were used to construct monthly median profiles of nitrate. Monthly nitrate inventories were calculated for each zone by integrating the median profiles between the surface and a depth of 100 or 200 m. Three methods were utilized to estimate NCP from the nitrate drawdown. The resulting mean NCP estimates indicated a decline in NCP from 3 to 4 mol C m−2 yr−1 south of ∼40°S to ≤1 mol C m−2 yr−1 north of ∼40°S. The monthly median profiles suggested 20%–100% of drawdown occurred by the end of December; however, chlorophyll fluorescence indicated phytoplankton activity persisted through austral summer. We speculate that primary production during these summer months was supported by regenerated nitrogen sources (not nitrate), despite replete concentrations, likely due to the relative scarcity of bioavailable iron known to persist in the region. While a northward advective flux of nitrate was strongly suggested by meridional nitrate gradients over the upper 0–300 m, vertical mixing was apparently necessary to stimulate new production, indicating both processes are important for NCP in the Argentine Basin. This work highlights the potential for floats in studying biogeochemical cycles in hydrographically complex regions.
On Groundwater Recharge in Variably Saturated Subsurface Flow Models
Authors: Gong Chengcheng , Cook Peter G. , Therrien René , Wang Wenke , Brunner Philip 
Published: August 2023

AbstractGroundwater models that simulate only saturated flow use groundwater recharge as an input parameter. In contrast, variably saturated subsurface flow models, including integrated surface and subsurface hydrologic models, can jointly simulate the movement of water in the saturated and unsaturated zones. Instead of recharge, they require climate data such as precipitation and potential evapotranspiration. Given that the latter models represent hydrological processes operating throughout the unsaturated zone and at the water table, one might expect that recharge can be readily extracted from them. In this paper, we demonstrate that it is not the case. When the commonly used definitions of groundwater recharge are implemented in variably saturated subsurface flow models, they do not yield meaningful results. Above all, the problems occur because of the storage dynamics in the capillary fringe above the water table. Despite this difficulty, variably saturated subsurface flow models can provide the information required for water resources management directly.
NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice
Authors: Cheng Cheng , Zhang Jie , Li Xiaodong , Xue Fei , Cao Lei , Meng Linlin , Sui Wenhai , Zhang Meng , Zhao Yuxia , Xi Bo , Yu Xiao , Xu Feng , Yang Jianmin , Zhang Yun , Zhang Cheng 
Published: August 2023

AbstractPrevious studies suggested a beneficial effect of natriuretic peptides in animal models of cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the pathogenesis of atherosclerosis (AS) remains unknown. This study was designed to test the hypothesis that NPRC may promote AS lesion formation and instability by enhancing oxidative stress, inflammation, and apoptosis via protein kinase A (PKA) signaling. ApoE−/− mice were fed chow or Western diet for 12 weeks and NPRC expression was significantly increased in the aortic tissues of Western diet-fed mice. Systemic NPRC knockout mice were crossed with ApoE−/− mice to generate ApoE−/−NPRC−/− mice, and NPRC deletion resulted in a significant decrease in the size and instability of aortic atherosclerotic lesions in ApoE−/−NPRC−/− versus ApoE−/− mice. In addition, endothelial cell-specific NPRC knockout attenuated atherosclerotic lesions in mice. In contrast, endothelial cell overexpression of NPRC aggravated the size and instability of atherosclerotic aortic lesions in mice. Experiments in vitro showed that NPRC knockdown in human aortic endothelial cells (HAECs) inhibited ROS production, pro-inflammatory cytokine expression and endothelial cell apoptosis, and increased eNOS expression. Furthermore, NPRC knockdown in HAECs suppressed macrophage migration, cytokine expression, and phagocytosis via its effects on endothelial cells. On the contrary, NPRC overexpression in endothelial cells resulted in opposite effects. Mechanistically, the anti-inflammation and anti-atherosclerosis effects of NPRC deletion involved activation of cAMP/PKA pathway, leading to downstream upregulated AKT1 pathway and downregulated NF-κB pathway. In conclusion, NPRC deletion reduced the size and instability of atherosclerotic lesions in ApoE−/− mice via attenuating inflammation and endothelial cell apoptosis and increasing eNOS expression by modulating cAMP/PKA-AKT1 and NF-κB pathways. Thus, targeting NPRC may provide a promising approach to the prevention and treatment of atherosclerosis.
Real-world experience of patients with multiple myeloma receiving ide-cel after a prior BCMA-targeted therapy
Authors: Ferreri Christopher J. , Hildebrandt Michelle A. T. , Hashmi Hamza , Shune Leyla O. , McGuirk Joseph P. , Sborov Douglas W. , Wagner Charlotte B. , Kocoglu M. Hakan , Rapoport Aaron , Atrash Shebli , Voorhees Peter M. , Khouri Jack , Dima Danai , Afrough Aimaz , Kaur Gurbakhash , Anderson Larry D. , Simmons Gary , Davis James A. , Kalariya Nilesh , Peres Lauren C. , Lin Yi , Janakiram Murali , Nadeem Omar , Alsina Melissa , Locke Frederick L. , Sidana Surbhi , Hansen Doris K. , Patel Krina K. , Castaneda Puglianini Omar Alexis 
Published: August 2023

AbstractMost patients with multiple myeloma experience disease relapse after treatment with a B-cell maturation antigen-targeted therapy (BCMA-TT), and data describing outcomes for patients treated with sequential BCMA-TT are limited. We analyzed clinical outcomes for patients infused with standard-of-care idecabtagene vicleucel, an anti-BCMA chimeric antigen receptor (CAR) T-cell therapy, at 11 US medical centers. A total of 50 patients with prior BCMA-TT exposure (38 antibody-drug conjugate, 7 bispecific, 5 CAR T) and 153 patients with no prior BCMA-TT were infused with ide-cel, with a median follow-up duration of 4.5 and 6.0 months, respectively. Safety outcomes between cohorts were comparable. The prior BCMA-TT cohort had a lower overall response rate (74% versus 88%; p = 0.021), median duration of response (7.4 versus 9.6 months; p = 0.03), and median progression-free survival (3.2 months versus 9.0 months; p = 0.0002) compared to the cohort without prior BCMA-TT. All five patients who received a prior anti-BCMA CAR T responded to ide-cel, and survival outcomes were best for this subgroup. In conclusion, treatment with ide-cel yielded meaningful clinical responses in real-world patients exposed to a prior BCMA-TT, though response rates and durability were suboptimal compared to those not treated with a prior BCMA-TT.