bluuebunny/crossref_metadata_2025_split huggingface dataset:
Islamic teachings and religious brotherhood in the Islamic society
Authors: Jamil M. , Abbas Syed Z. , Abdel Amir Al-Salami Ammar , Ali Hussein Al-Khafaji Forqan , Ryafikovna Saenko Natalya , Alexis Ramírez-Coronel Andrés 
Published: April 2023

The Holy Qur’an relates believers’ pure emotions to brotherhood. From the perspective of Islam, it has been also affirmed that two people have the same thoughts and opinions in one centre point of love in brotherhood, so fraternal feelings are not merely limited to kinship and consanguinity. In this line, the Holy Qur’an states that we have come to make you brothers with each other; not a brotherhood from parents, but an Islamic one, which is highly appreciated in the Islamic society. In addition, a believing brother can never be filled when his fellow believer is hungry, and he cannot be clothed while the other is with nothing on. Islam further considers all Muslims as one family and calls everyone brothers and sisters or siblings. The true Muslims of any race and tribe as well as any language and age thus have a deep sense of brotherhood with each other, even if one lives in the Eastern parts of the world and the other in the West. In sum, this article aimed to investigate the role of religious teachings in strengthening believers’ brotherhood in the Islamic society. For this purpose, firstly, the definition of religious brotherhood was provided; secondly, religious brotherhood has been described based on the Holy Qur’an.Contribution: This article helped gain a new insight into the role of Islamic teachings in strengthening religious brotherhood in the Islamic society. Besides, the indicators of religious brotherhood were extracted and then enlightened according to the Ayat (viz. verses) from the Holy Qur’an.
The transformation of theology in the present climate crisis
Authors: Moltmann Jürgen 
Published: April 2023

Humanity is facing an ecological catastrophe. Culprits include a linear understanding of time which looks only to the future and the human belief in progress. This ideology has remained the same in the search for solutions; technological progress must provide the answer. However, the article argued that a green transformation is needed. Ecological justice is required. Not only the rights of humans but also of nature, the earth and animals should be respected. Ecological justice and social justice are connected. This pertains to the rights of future generations to achieve a green transformation of urban life (Moltmann 2019:87).The article proposed three changes. Firstly, nature should no longer be seen and treated by humans as an object to be exploited but instead as a fellow subject in the green creation community. Secondly, humanity should be seen as embedded in this community of creation. Thirdly, a new cosmic spirituality with a deep respect for life and everything that lives is needed.Contribution: This article exposed and overturned the much taken-for-granted paradigm of progress towards the future that currently dominates humanity. It illustrated the consequences of this way of thinking. It proposed a radically different yet simple, spiritual and highly respectful alternative view of creation.
COVID-19 crisis in relation to religion, health and poverty in Zimbabwe: A case study of the Harare urban communities
Authors: Muyangata Joseph , Shumba Sibiziwe 
Published: April 2023

The COVID-19 pandemic which started in China in 2019, was originally described as a public health emergency of intercontinental concern by the World Health Organization (WHO) in January 2020. Due to its speedy rate of spread, the WHO then declared it a pandemic after 6 weeks. The global spread of COVID-19 has been attributed to the high mobility between and within countries. Having noted the wide spread of the COVID-19 pandemic, almost every country affected, developed strict and restrictive public health measures to control the spread of the virus. Such measures included restrictions on country borders and social gatherings. Hence, the main purpose of the paper was to explore the impact of the COVID-19 crisis in relation to religion, health and poverty in Harare urban communities as well as determining solutions to the impact of the COVID-19 pandemic on those sectors. The research methodology was qualitative in nature. Primary data were collected through in-depth telephone interviews and online open-ended questionnaires. Purposive sampling was used to select the study participants. The findings showed that the COVID-19 pandemic triggered and exposed the inequalities in health. The pandemic also had a strong impact on religious activities and it exacerbated poverty levels as well. Those who had all the access to medication, food and vaccinations during the height of COVID-19 may not fully appreciate the impact that poverty coupled with pandemics left on their communities both religiously and socially. Malnutrition, hunger and sickness were the order of the day among the poor.Contribution: The conclusion was that COVID-19 negatively impacted on the health, religious and social sectors. Therefore, it is critical to maintain preventive and curative services, especially for the most vulnerable populations such as children, older persons, and people with disabilities.
Biblical interpretation during the era of the COVID-19 pandemic: Perspectives from Africa
Authors: Aryeh Daniel N.A. , Molobi Victor V.S. 
Published: April 2023

Biblical interpretation and/or hermeneutics is largely influenced by context and prevailing events and/or issues. This is attested by many scholars in the field. Previous pandemics have influenced the way biblical hermeneutics is conducted during the period. The situation is not too different from the emergence of COVID-19. The pandemic has been scripturalised to argue that it is the fulfilment of scriptural signs for the second coming of Jesus. Others assert that it is the result of human sins and 5G technology. Amid these propositions, biblical narratives concerning miracles/healing, eschatology, and hope were handled uniquely. This study employs narrative research criticism to analyse various propositions concerning COVID-19 and how biblical texts were engaged to propound an epideictic rhetorical theory of biblical interpretation during the emergence of COVID-19. The main finding is that although there are many assigned eschatological interpretations to the pandemic, there is an epideictic interpretation of miracle narratives of Jesus to minister healing to persons affected and infected by COVID-19.Contribution: This study emphasises the problem-solving approach to biblical interpretation in the African context. It proposes the application of this approach in response to the impact of the COVID-19 pandemic.
Proverbs 31 in dialogue with Acts 9:36–43: An Afro-feminisation of Mother Earth for equity
Authors: Juma Dorcas C. 
Published: April 2023

A close relationship between masculinity, alcoholism, widowhood and gendered poverty is evident in contemporary African society. Alcohol consumption among young men begins at an increasingly early age due to availability of low-priced alcohol presented in different varieties. Young, beautiful and sexy girls are used to advertise alcohol. Many young men are addicted to alcohol and totally unable to be free from alcohol addiction. This sad state coupled with the impact of globalisation on the economies of many African countries has left many men jobless. Consequently, many households are headed by women in a patriarchal context where men are supposed to be the heads of the family. Through an Afro-feminisation of Mother Earth lens, this article re-read Proverbs 31 in dialogue with Acts 9:36–43, to show the role of women in the socio-economic sustainability of the family, society and in enhancing gender equity.Contribution: This article re-read Proverbs 31 in dialogue with Acts 9:36–41 as resources for enhancing gender equity. An Afro-feminisation of Mother Earth for sustainable development was presented in ways that open up possibilities for the life of the Garden of Eden in Genesis 1:28 to flourish.
Seroprevalence and factors associated with Coxiella burnetii exposure in goats in Moretele
Authors: Magadu Rungano , Thompson Peter N. 
Published: April 2023

Infection with Coxiella burnetii causes significant economic impact and poses zoonotic risk to people exposed to livestock, yet few studies in South Africa have assessed seroprevalence of C. burnetii infection and no information is available for goats. Very little information is available regarding risk factors and outcomes of C. burnetii infection in peri-urban farming areas where widespread mixing of ruminants occurs. This study estimated the seroprevalence of C. burnetii infection among communally farmed goats in an area adjacent to the densely populated Gauteng province. Sera were collected from 216 goats in 39 herds, and questionnaires were completed to establish management practices as potential risk factors. C. burnetii antibody testing was done by ELISA. Thirty two out of 216 goats tested positive for C. burnetii antibodies and the overall seroprevalence, adjusted for sampling weights and clustering, was 18.4% (95% confidence interval [CI]: 12.2% – 23.5%). The intraclass correlation coefficient was 0.06, indicating low-to-moderate clustering. Multiple logistic regression showed age was significantly associated with seropositivity, with higher seroprevalence in animals ≥ 19 months old (26%) than animals ≤ 6 months old (6%) (odds ratio [OR]: 6.6; p = 0.010). We concluded C. burnetii infection is common in goats in Moretele and a potential cause of abortion in goats and poses the potential zoonotic disease risk.Contribution: Despite the threats posed on animal health and productivity, scant information is published on C. burnetii in South Africa. This research established preliminary estimates of C. burnetii seroprevalence. The research is original from a South African perspective, relevant to Africa and focused on infectious disease in livestock.
Teaching comprehensive sexuality education using a praxis co-created with adolescents
Authors: Koch Ronél , Beyers Christa 
Published: April 2023

Background: Despite its reported positive deliverables, comprehensive sexuality education (CSE) in South African schools is unable to document an influence in reducing alarming statistics regarding adolescent sexual health. Prior research points to a gap that exists between what studies suggest and what is implemented in practice.Aim: Drawing on Freire’s theory of praxis, the aim of this study was to involve the voice of adolescents in reforming CSE – specifically, how the programme could be developed with the objective to co-construct a praxis in order to support sexuality educators in a delivery of CSE that is more responsive to the needs of adolescents.Setting: Ten participants were purposively selected from all five school quintiles in the Western Cape province of South Africa to take part in this study.Methods: A qualitative descriptive design with aspects of a phenomenological approach was utilised. Rich data were collected by means of semistructured interviews and were analysed thematically with ATLAS.ti.Results: The results illustrate the suggestions made by the participants towards the improvement of the CSE programme. They reported on approaches and strategies used to teach CSE that imply that it is often not delivered comprehensively – confirming the disjuncture between what the curriculum envisages and what is executed in practice.Conclusion: The contribution might lead to change in disconcerting statistics and consequently an improvement in the sexual and reproductive health of adolescents.Contribution: The participants from this study assisted in co-constructing a praxis for CSE teachers to inform their practice.
A retrospective analysis of irinotecan and bevacizumab combination therapy in recurrent high-grade glioma and glioblastoma multiforme
Authors: Palkonda Vijay Anand Reddy , Muddana Sai Tejaswini , Pathri Karthik , Reddy P Vijay Karan 
Published: April 2023

Introduction:
High-grade gliomas comprise central nervous system (CNS) World Health Organization (WHO) Grade 3 and CNS WHO Grade 4 gliomas. Recurrence is seen in almost all patients who underwent treatment. Recurrent high-grade gliomas have poor prognosis. There are phase two trials that assessed the role of irinotecan and bevacizumab as combination regimen in recurrent High-grade gliomas and showed overall survival (OS) and progression-free survival (PFS) benefit. We did a retrospective analysis of our institutional experience on treating recurrent high-grade gliomas with combination of irinotecan and bevacizumab.

Materials and Methods:
This was a retrospective analysis including 58 patients treated at our center from January 1, 2010 to December 31, 2020. All patients were diagnosed case of CNS WHO Grade 3 and Grade 4 glioma, who received at least one modality of treatment. All patients received inj. Irinotecan 125 mg/m2 intravenous (IV) and inj. Bevacizumab 10 mg/kg IV, every 2 weekly. A base line radiological evaluation has been done with magnetic resonance imaging brain with contrast and repeated every 3 months. Patients have been assessed both for PFS and OS.

Results:
Median PFS was 6 months (95% confidence interval [CI] 4.395–7.605). Median OS was 8 months (95%CI 5.894–10.106). Six months PFS rate is 49% and 6 months OS is 58%. CNS WHO Grade 3 gliomas responded better to combination therapy as compared with CNS WHO Grade 4 gliomas.

Conclusion:
Combination of Bevacizumab and Irinotecan is well tolerated and improves OS and PFS in patients with recurrent high-grade gliomas. The effect of combination systemic therapy is more evident in CNS WHO Grade 3 gliomas as compared with glioblastoma multiforme.
Ocular conjunctival microbiome profiling in dry eye disease: A case control pilot study
Authors: Gupta Noopur , Chhibber-Goel Jyoti , Gupta Yogita , Mukherjee Souvik , Maitra Arindam , Sharma Amit , Tandon Radhika 
Published: April 2023

Purpose:
Keratoconjunctivitis sicca (KCS) or dry eye disease (DED) is a multifactorial disease that results in discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. A pilot study was undertaken to determine if there were any major substantial differences in the ocular microbiome in DED patients versus healthy controls.

Methods:
The bacterial communities residing in the conjunctiva of patients with DED (n = 4) and healthy controls (n = 4) were assessed by 16S ribosomal RNA (rRNA) gene sequencing of the V4–V5 region.

Results:
The phyla Proteobacteria, Actinobacteria, Bacteroidetes, and Firmicutes were most dominant and accounted for 97% and 94.5% of all bacterial sequences in patients and controls, respectively. At the genus level, 27 bacterial genera were found with more than two-fold difference between patients and controls. Four of these – Acinetobacter, Corynebacterium, Lactobacillus, and Pseudomonas spp. – dominated the ocular microbiome of all subjects, but were proportionately lower in DED (16.5%) compared to controls (37.7%). Several bacterial genera were found to be unique in DED (34) and controls (24).

Conclusion:
This pilot study is an attempt to profile the ocular microbiome in patients with DED that demonstrated a higher concentration of microbial DNA compared to controls, with Firmicutes phyla dominating the bacterial population in patients with DED.
Impact of ocular care training of nursing staff on the incidence of ocular surface disorder in medical intensive care unit patients
Authors: Pai Aditi , Kamath Atul , Vasava Indravadan , Bhosale Dhananjay , Nambiar Gokulnath 
Published: April 2023

Purpose:
To assess the knowledge of nursing staff on ocular care in medical intensive care unit (ICU) and to compare the incidence of ocular surface disorders in patients of medical ICU pre- and post-training.

Methods:
Two hundred patients admitted in medical ICU for more than 24 h underwent a detailed ocular examination along with documentation of ICU stay, ventilation status, and Glasgow coma scale (GCS) scoring. An assessment on ocular care knowledge among the nursing staff of medical ICU was done. They were further given training in the form of audio-visuals and demonstration, and an eye care protocol was given to them. The second phase of the study was carried out in the same manner. A comparison was made between pre-training and post-training incidence of ocular surface disorders among ICU patients.

Results:
Ventilated patients had more eye discharge. Incidence of eye discharge was more in patients with duration of stay of more than 7 days in ICU. Ocular surface disorders closely correlated with the degree of lagophthalmos. There was significant reduction in ocular morbidity following ocular care training of the nursing staff.

Conclusion:
Eye care is a very important part of nursing care in sedated and ventilated patients in the ICU. Ophthalmic consultations are routinely needed in ICU subjects who are hospitalized for more than 1 week or if the ICU staff suspects any eye problems.
Functional and morphological evaluation of the meibomian glands and ocular surface assessment at high altitude
Authors: Li Zhouyu , Wan Wenjuan , Ji Yan , Zheng Shijie , Hu Ke 
Published: April 2023

Purpose:
To compare the function and morphology of the meibomian glands and the ocular surface of individuals from highland and lowland.

Methods:
This was a randomized controlled trial. The study was performed with 104 individuals (51 individuals from the highland and 53 individuals from the lowland). Detailed eye examinations comprising tear meniscus height, lipid layer grading, non-invasive Keratograph tear breakup time (NIKBUT), and scoring of the meibomian glands from the upper and lower eyelids of the individuals were performed by Keratograph 5M (OCULUS, Wetzlar, Germany). Symptoms related to dry eye disease were assessed using the Ocular Surface Disease Index (OSDI).

Results:
In the highland group, tear meniscus height was lower (P = 0.024), lipid layer grade, as well as all the meiboscores were higher (P < 0.05) than that in the lowland group. The OSDI (P = 0.018) and the percentage of dry eye disease were also higher as compared to that of the lowland group (P = 0.032). The first NIKBUT and average NIKBUT did not differ significantly between groups. The frequency of plugged meibomian gland orifices was greater in the lowland group compared to the highland group (P = 0.036).

Conclusion:
It was observed that dry eye disease was more common in the highland group. The morphological changes of meibomian gland dropout were significant in highlanders as demonstrated objectively with Keratograph 5M. Our study may raise a concern for environmental influences on ocular surface changes.
Dry eye disease in head and neck cancer patients undergoing radiotherapy
Authors: Soni Meenal , Walia Shweta , Jain Preety 
Published: April 2023

Purpose:
To study the incidence of dry eye disease (DED) in head and neck cancer (HNC) patients undergoing external beam radiotherapy (EBRT), to find a correlation between tumor location and total radiation dose with DED, and to report various radiotherapy (RT) induced acute toxic effects on ocular and adnexal structures.

Methods:
A prospective cohort study was conducted at a tertiary eye-care center on 90 patients of HNC undergoing EBRT from March 2021 to May 2022. All underwent a thorough clinical history and complete ophthalmological examination including an ocular surface disease index (OSDI) questionnaire, visual acuity, anterior segment, angle and posterior segment examination, dry eye workup including the Schirmer test, tear meniscus height, tear break-up time, corneal fluorescein staining and grading, and meibography by auto-refractometer and its scoring at each visit. Patients were evaluated before the start of RT and then at 1 week, 4 weeks, and 12 weeks post-RT. Radiation records of all patients were noted. Data were analyzed using percentage and Microsoft Excel.

Results:
Of the 90 patients, 66 were male and 24 female (M: F ratio of 2.75) with a median age of 52.5 years (range 24 to 80 years). The most common HNC was the carcinoma oral cavity and lip. Most patients received a total radiation dose between 46 to 55 Gy. DED developed in 48 (53.3%) patients. The incidence of DED increased with the increase in total radiation dose (r = 0.987). DED was also found to be correlated with tumor location (r = 0.983).

Conclusion:
The incidence of DED positively correlated with the total radiation dose and tumor location.
Comparative evaluation of effectiveness of twenty versus fifty percent autologous serum eye drops in treatment of dry eye
Authors: Kumari Neha , Kusumesh Rakhi , Kumari Rekha , Sinha Bibhuti Prassan , Singh Vivek 
Published: April 2023

Purpose:
The objective of the study was to compare the efficacy and safety of two concentration of autologous serum (AS) 20% vs 50% in recalcitrant moderate-to-severe dry eye patients.

Methods:
A double-blind prospective, interventional, and randomized study was done on 44 patients (80 eyes) clinically diagnosed with moderate-to-severe dry eye disease (DED) that was refractory to conventional treatment, and all patients were treated with AS20% or AS50% for 12 weeks. We documented Ocular Surface Disease Index (OSDI), tear film breakup time (TBUT), OXFORD corneal staining score (OSS), and Schirmer test (ST) at baseline, 2,4,8, and 12 weeks. These parameters were compared in both groups and between the groups by using Student’s t-test. The study included 11 males and 33 females.

Results:
Out of 80 eyes, 33 eyes had moderate and 47 had severe DED. The age of patients in AS20% was 44.73 ± 14.37 years, and in AS50% was 46.41 ± 14.47 years. The most common etiology associated with DED was secondary Sjogren syndrome. In moderate DED, both the groups showed significant improvement in both subjective and objective parameters. But in severe DED, the AS20% group failed to show any significant improvement objectively, though subjective improvement was present.

Conclusion:
In refractory severe DED patients, AS50% is better option for treatment and in moderate DED both concentrations of autologous serum are effective.
Prevalence of dry eye disease in the patients of allergic conjunctivitis: Hospital-based cross-sectional study
Authors: Mazumdar Shefali , Satsangi Saran Kumar , Garg Mahak , Rajan Payal Goel 
Published: April 2023

Purpose:
Allergic conjunctivitis (AC) is commonly associated with dry eye. This study was conducted to assess the prevalence of dry eye in different subsets of AC patients.

Methods:
This observational, cross-sectional study, conducted in the Department of Ophthalmology of a tertiary center in north India, included 132 patients of AC. The diagnosis of dry eye disease (DED) was made on the basis of Ocular Surface Disease Index (OSDI), Schirmer’s test, and tear film break-up time (TFBUT).

Results:
The prevalence of dry eye in AC patients was found to range between 31% and 36%. On OSDI scoring, 20.45% of patients had mild, 18.18% moderate, and 31.81% had a severe grade of DED, respectively. The mean OSDI score was noted to be significantly higher in patients with perennial allergic conjunctivitis (PAC) (29.82 ± 12.41), followed by seasonal allergic conjunctivitis (SAC) (25.35 ± 12.88), and least in the patients of vernal keratoconjunctivitis (VKC) (13.60 ± 8.63) (p < 0.0001), respectively. The TFBUT was found to be less than 10 s in 45.45% of PAC, 30.43% of SAC, and 20% of VKC patients, respectively. The difference between the mean TFBUT among the three groups was statistically insignificant (p = 0.683). Schirmer’s test value of <10 mm was observed in 45.45% of PAC, 43.47% of SAC, and 10% of VKC patients, respectively.

Conclusion:
This study revealed a high prevalence of DED in patients with AC. Among the different types of AC patients, PAC had the highest percentage of DED followed by SAC and least in VKC, respectively.