bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Quality Analysis of Web-Based Library Information System based on ISO 9126 Standard
Authors: Akhsan Rivaldi Rizalul , Apriliasari Dewi , Mangesa Riana Tangkin 
Published: June 2023

Management of book collection at the Department of Electrical Engineering, State University of Malang is less effective and efficient because the management process is carried out manually and centrally on a single computer (stand alone). This research purposes is to describe, develop, and test a reference book management information system based on Model View Controller (MVC) in the Department of Electrical Engineering, State University of Malang. The development model that used in this research is waterfall model which consists of analysis, design, implementation, and testing step. Testing is carried out to determine the quality of the developed system. Testing of the product in this research is using ISO 9126 indicators with aspects of functionality, and usability. The results showed that: (1) the reference book management information system was developed using the Codeigniter framework and the waterfall development model consisting of the needs analysis, design, implementation, and testing step, and (2) the test results on the functionality aspect obtained a value of 1 ( good). Usability testing obtained a result of 4.03 (very feasible) obtained from the results of the average assessment of students and librarian responden.
ПРАКТИЧНА ОЦІНКА РЕАЛІЗАЦІЇ РОЗПОДІЛЕНОГО КРИПТОАНАЛІЗУ В УМОВАХ ОБМЕЖЕНИХ РЕСУРСІВ
Authors: Носов Віталій , Лучик Василь , Колісник Тетяна , Калякін Сергій , Світличний Віталій 
Published: June 2023

Оперативні підрозділи відповідних спеціальних служб і органів державної влади при здійсненні своїх повноважень часто стикаються із задачею здійснення криптоаналізу отриманих зашифрованих даних. На практиці оперативне криптографічне розкриття таких даних зазвичай має дві суттєві обставини: відсутність спеціалізованих обчислювальних ресурсів та наявність лише обмеженої кількості персональних комп'ютерів з ОС Windows. Одним із актуальних способів підвищення ефективності криптоаналізу в таких умовах є реалізація паралельних розподілених клієнт-серверних обчислень на базі локальної мережі персональних комп'ютерів з ОС Windows, де сервер через деякий інтервал часу розподіляє виділені підмножини простору можливих ключів шифрування між агентами в локальній мережі, які в свою чергу передають задачу перебору ключів відповідній локальній програмі. Здійснений перший етап практичної оцінки застосунку Hashtopolis як інструмента розподіленого криптоаналізу в умовах обмежених ресурсів. Hashtopolis є працездатним у локальній мережі персональних Windows комп'ютерів і може бути використаний на практиці. Зростання швидкості паралельних обчислень не є прямо пропорційним кількості агентів, оскільки витрачається час на формування підмножин простору ключів, їхнього доставлення агентам та отриманням результатів перебору ключів. Практична оцінка Hashtopolis потребує подальшого дослідження зростання продуктивності його роботи у залежності від кількості агентів, інших типів ґешів і типів криптоаналізу (за словником, комбінований) та контролю температури процесорів на агентських машинах. Ідентифікована задача оптимального вибору для агентів розміру підмножини простору можливих ключів в залежності від кількості агентів, їх поточної швидкості перебору, алгоритму ґешу і типу перебору.
Impact of quarry activities on the air quality around neighbouring localities in Ogun State, Nigeria
Authors: Hassan Isiaka Adio 
Published: June 2023

Quarry industry and its products play an important role in any economy in the world. This study examined the impact of quarry activities on air quality around the neighbouring localities in Ogun State. Eight locations were selected; Isara, Idode, Iwaye, Ogbere, Ilagbe, Adelokun, Baaki Ake, and Igodo. Air quality was assessed for the concentration of CO2, PM2.5 and PM10 using standard procedures. Samplings were carried out in dry and wet seasons. Data were subjected to descriptive and inferential statistics using SAS package (9.4 version), compared with World Health Organisation (WHO) and the probability of particulate matters causing health hazard was also calculated using Air Quality Index (AQI). PM2.5 and PM10 (dry season) of the surrounding locations were higher than the WHO Limits of 15 and 45 µg/m3 respectively; except the PM10 at Iwaye (32.20±4.18 µg/m3), Isara (35.60±4.38 µg/m3) and Adelokun (42.58±2.74). In wet season, the PM2.5 (all locations) and only PM10 of Ilagbe ((45.99±3.15), Baaki Ake (50.97±3.13) and Igodo (49.68±2.17) were higher than their corresponding WHO Limits. The AQI of PM2.5 (both seasons) at various locations were in the range of 51 – 100 (moderate). AQI of PM10 dry and wet seasons across locations range 0 – 50 (good); except the PM2.5 of Baaki Ake (51.16) hence, moderate. CO2 concentration at Adelokun (421.73±2.75), Baaki Ake (415.62±5.82) and Igodo (411.85±1.95) (dry season) and Adelokun (405.98±2.60) and Baaki Ake (403.26±1.63) (wet season) surpassed WHO limit (400 µg/m3). The surrounding localities were polluted with CO2 and particulate matters (PM2.5 and PM10) with no health hazard.
Blood Pressure and anthropometry obesity indices in first professional medical students at a private medical college of Pakistan-a cross-sectional study
Authors: Zafar Uzma , Usman Ul Haque Muhammad , Jabeen Naeem Faiqa , Sufyan Musfirah , Usman Naeem Muhammad 
Published: June 2023

Obesity, a significant public health issue, requires immediate attention to prevent obesity-mediated health concerns such as hypertension, metabolic syndrome, and adverse coronary and circulatory events. The present study aimed to determine blood pressure (BP) and anthropometric obesity indices (including BMI, waist circumference, waist-to-hip ratio, and mid-upper arm circumference) of 1st Professional MBBS students in a private medical college in Pakistan, and also to find the association of BP with anthropometric indices. It was a cross-sectional survey conducted at Lahore Medical and Dental College. Institutional Review Board approval was acquired before the study commencement. The duration of the study was from May to August 2022. The study population included all students registered in first-year MBBS who agreed to participate in the study. The present study included 120 participants. The mean ± standard deviation (SD) age of participants was 19.05±0.82 years. Mean systolic and diastolic BP was 116.05±13.21 and 74.85±9.81 respectively. Sixty-seven (56%) participants were having their BP ≥ 120/80 and were identified as pre-hypertensive or hypertensive respectively. Mean ± SD BMI was 22.18±4.31 kg/m2; 67 (55.8%) were having normal BMI, 20(16.7%) were overweight and 33 (27.5%) obese. On the basis of waist circumference; 39 (70.9%) male subjects were normal and 16 (29.1%) centrally obese, whereas 47 (72.3%) females were normal and 18 (23.7%) obese. Overall central obese subjects were 35 (29%). Logistic regression analysis was applied; hypertension was taken as a dependent variable and all-other independent covariates such as anthropometry indices (BMI, waist circumference), gender, age, and residential status were controlled; association of hypertension was significant with gender (p=0.001) and waist circumference (p=0.000). Students need to modify lifestyle strategies for preventing obesity and hypertension.
Flipchart and Booklet As Media to Increase Cadre’s Knowledge About Latent Tuberculosis Prevention in Children
Authors: Retno Asih Setyoningrum  , Arda Pratama Putra Chafid  , Rika Hapsari  , Amrina Rosyada  , Muhammad Helmi Imaduddin  , Khoirunnisa Shafira Deshpande  , Nabila Annisa Harum  
Published: June 2023

Educating and empowering the community through tuberculosis cadres is crucial in the early detection of latent tuberculosis infection (LTBI) in primary healthcare settings. From the wide variety of educational media that can be used, flipcharts and booklets have a strong impact on engaging the participants through visual media. Therefore, this community service aims to determine the effect of education through flipcharts and booklets on TB cadres to increase LTBI finding in children. A total of 20 TB cadres of Dr. Soetomo Primary Health Care Surabaya participated in this study. Statistical analysis to evaluate the difference between the pre-test and post-test was used with the Wilcoxon test. The result of the pretest showed insufficient knowledge about latent tuberculosis with an average score of 74%. The post-test average score of 91% indicated a 17% increase in score. There was a significant difference in the score of the test before and after giving the material (p=0.001), indicating an increase in LTBI knowledge of the TB cadres after giving health education using flipchart and booklet as evidenced by the increase in average score between pre-test and post-test.
Case Study of the Use of a Digital Twin for Leak Detection and Quantification in Underground Gas Storage Wells
Authors: Abdo Elia , Baronio Emanuele , Mauro Stefano , Troise Mario , Salamina Laura 
Published: June 2023

Summary
Underground gas storage (UGS) wells are essential components in energy security. However, UGS wells present a complicated and delicate combination of elements where ensuring safe and secure functionality over long periods is paramount. This paper showcases how a digital twin is used to evaluate and forecast the link between leaks and temperature and pressure trends in a UGS well, allowing the identification and quantification of defects and, subsequently, well barrier integrity. The digital twin used for this application presents advantages compared with other solutions present on the market with regard to the simplified configuration; that is, with minimal input data, the system can produce an accurate and useful output, which is then used in the well integrity decision-making process.
UGS wells present additional criticalities with respect to normal production wells due to their longer life span and the repetitive production and injection cycles. This makes early and accurate leak detection essential for the safe management of the well barriers. The proposed digital twin simulates the trends of pressure and temperature within each annulus and compares results with data from the field, allowing the identification of the position and size of leaks. A genetic algorithm is applied to optimize the placement of leaks on their specific barriers. Once a leak is identified, a risk assessment is conducted to evaluate the overall integrity of the well. If the status of the well is found to be critical enough, an intervention may be planned.
The studies presented show how the digital twin has been used on two wells with similar problems. At first, it has confirmed the necessity to put the well out of service as opposed to planning maintenance, thereby saving both time and cost. In the second case, it allowed the validation of a solution that led to a 60% reduction in failure consequence, allowing the well to continue operating without major costs or risks. The errors of the resulting simulations were always confined within the 0.5 bar limit highlighting its accuracy.
The system has been in use for over a year and has shown great potential in accurate and efficient identification of leaks. This has accelerated the process of well integrity evaluation and allowed timely interventions on wells that required it. On the other hand, the process has highlighted cases where previous assumptions about leak location and size were corrected using the digital twin, therefore reducing the costs of interventions. Finally, the model showcases a clear readiness for predictive capabilities aimed to select, plan, and design fit for purpose mitigating actions.
Laparoscopic cholecystectomy for xanthogranulomatous cholecystitis: 18 years of experience.
Authors: Zubillaga-Mares Asya , Renteria-Palomo Enrique , Hall-Ramirez William Bryan , Lopez-Godinez Maria Fernanda , Nuñez-Venzor Alejandra , Cardenas-Lailson Eduardo 
Published: June 2023

Abstract
Background Xanthogranulomatous cholecystitis (XG) is a rare inflammatory disease of the gallbladder (GB), macroscopic appearance may be confused with gallbladder cancer (GC) making the diagnosis challenging. Laparoscopic cholecystectomy (LC) is considerate the gold standard for the management of benign gallbladder disease however LC in XGC is associated with a high conversion rate to open cholecystectomy with a rate of 10.6 to 80%. The aim of this study was to determinate the rate of laparoscopic cholecystectomy on patients with histopathological diagnosis of CXG and the associated morbidity to the procedure.
Material and methods This study is an observational, retrospective, and cross-sectional study carried out over a period of 18 years in a single institution. Patients underwent to laparoscopic cholecystectomy with histopathological diagnosis of xanthogranulomatous cholecystitis were included. The primary outcome was the rate of conversion to open surgery; secondary outcomes were the morbidity and mortality. The data were reported on percentages and averages. Statistical Package for the Social Sciences (SPSS, version 26) was used to analyze the data. The study was approved by the board of ethical committee in our institution in 2018.
Results We registered 142 patients operated from cholecystectomy with histopathologic results of XGC and 106 surgeries were performed laparoscopically (74.6%); 52 were emergency surgeries (49%) and 54 elective (51%). The conversion rate to open cholecystectomy was 3.7% (4 patients). There were 5 post-surgical complications (4.7%) two bilomas, one surgical site infection, and two biliary leak.
Conclusions XGX represents a surgical challenge from diagnosis to surgical management and is associated to a higher number of perioperative complications; nevertheless, a laparoscopic approach is safe in high volume centers with experience in laparoscopy.
Greedy Knot Selection Algorithm for Restricted Cubic Spline Regression
Authors: Arnes Jo Inge , Hapfelmeier Alexander , Horsch Alexander , Braaten Tonje 
Published: June 2023

Abstract
Non-linear regression modeling is common in many fields for prediction purposes or estimating relationships between predictor and response variables. For example, restricted cubic spline regression can model non-linear relationships as third-order polynomials joined at knot points. The standard approach is to place knots by a regular sequence of quantiles between the outer boundaries. A regression curve can easily be fitted to the sample using a relatively high number of knots. The problem is then overfitting, where a regression model has a good fit to the given sample but does not generalize well to other samples. A low knot count is therefore preferred. However, the standard knot selection process can lead to underperformance in the sparser regions of the predictor variable, especially when using a low number of knots. It can also lead to overfitting in the denser regions. We present a simple greedy search algorithm using a backward method for knot selection that shows reduced prediction error and Bayesian information criterion (BIC) scores compared to the standard knot selection process in simulation experiments. We have implemented the algorithm as part of an open-source R-package, knutar.
The effect of using desktop VR to practice preoperative handovers with the ISBAR approach: a randomized controlled trial
Authors: Andreasen Eva Mari , Berg Helen , Steinsbekk Aslak , Høigaard Rune , Haraldstad Kristin 
Published: June 2023

Abstract

Aim
The aim was to investigate whether second-year undergraduate nursing students practicing the Identification-Situation-Background-Assessment-Recommendation (ISBAR) communication approach in a desktop virtual reality (VR) application had a non-inferior learning outcome compared with the traditional paper-based method when sorting patient information correctly based on the ISBAR structure.
Methods
A non-inferior parallel group assessor blinded randomized controlled trial, conducted in simulation sessions as part of preparation for clinical placements in March and April 2022. After a 20-minute introductory session, the participants were randomized to self-practice the ISBAR approach for 45 minutes in groups of three in either an interactive desktop VR application (intervention) or traditional paper-based (TP) simulation. The primary outcome concerned the proportion of nursing students who sorted all 11 statements of patient information in the correct ISBAR order within a time limit of five minutes. The predefined, one-sided, non-inferiority limit was 13 percentage points in favor of traditional paper-based simulation.
Results
Of 210 eligible students, 175 (83%) participated and were allocated randomly to the VR (N = 87) or TP (N = 88) group. Practicing in the desktop VR application (36% of everything correct) was non-inferior to the traditional paper-based method (22% everything correct), with a difference of 14.2 percentage points (95% CI 0.7 to 27.1) in favor of VR. The VR group repeated the simulation 0.6 times more (95% CI 0.5 to 0.7). Twenty percent more (95% CI 6.9 to 31.6) of the students in the VR group reported liked how they practiced. All the other outcomes including the System Usability Scale indicated non-inferiority or were in favor of VR.
Conclusions
Self-practicing with the ISBAR approach in desktop VR was non-inferior to the traditional paper-based method and gave a superior learning outcome.
Trial registration number:
ISRCTN62680352 registered 30/05/2023.
Massage Manipulation and progression of osteosarcoma, Does It Really Correlate? : A Combination of Prospective and Retrospective Cohort Study
Authors: Karda I Wayan Arya Mahendra , Ismail Wan Faisham Wan , Kamal Achmad Fauzi 
Published: June 2023

Abstract
In Indonesia, the challenge of osteosarcoma progression is further worsened by patients' dependence on traditional massage therapy, low socio-economy, and educational status. This study aims to analyze the differences in the characteristics, laboratory findings, surgery techniques, degree of histopathological necrosis, and metastasis between osteosarcoma patients with and without prior massage manipulation therapy. This research is an analytical observational study with a prospective and retrospective cohort design. Patients were treated and followed for one year to evaluate the occurrence of metastasis. Prospective data was collected through interviews, and secondary data was collected from the patient's medical record. Of 84 subjects analyzed, 69% had a history of massage. There was an increase in LDH and ALP in patients with massage manipulation (p=0.026). The median time to metastasis from baseline in the massage group (4 months) was statistically significant compared to the non-manipulation group (12 months) (p<0.0001). This research found that massage therapy significantly increases LDH and ALP levels, making amputations more likely to be performed and a higher risk of metastasis that lowered the survival rate. The onset of metastasis was three times faster in patients with prior massage therapy. Therefore, we strongly recommend against massage manipulation therapy in osteosarcoma patients.
Clinical and radiological outcomes of patients treated with the Orthofix Chimaera Long nailing system for proximal and diaphyseal femoral fracture
Authors: TRAVERSO Aurelien , STEINMETZ Sylvain , NGO Trieu-Hoai-Nam , BORENS Olivier , CHERIX Stephane , MOERENHOUT Kevin 
Published: June 2023

Abstract

Background Intramedullary long nailing is a popular method to treat femoral shaft or sub-trochanteric fractures. Various complications have been described such as intraoperative anterior cortical perforation of the distal femoral shaft or post-surgical lateral thigh pain. In order to prevent those possible complications, a new intramedullary nailing system (Chimaera, Orthofix®) was designed. This study aims to evaluate the clinical and radiological results after antegrade intramedullary nailing of traumatic femoral shaft and inter-/subtrochantreric fractures.Methods A prospective cohort study was conducted on 20 consecutive patients with AO/OTA type 31A2.3-A3.3 and type 32A-C fractures treated with the Chimaera long nailing system from December 2017 to January 2021 at our level 1 trauma center. Parker & Palmer and Jenson scores were assessed at 3 months and compared to before the surgery. Radiologic assessment consisted in checking the position of the cephalic screw, using the tip-apex distance (TAD) and Cleveland zone. The mean follow-up was 12.5 (1–33) months.Results Parker and Palmer scores were equivalent to before the fracture for 4 patients (31%); minor changes were seen in 6 patients (46%). Jensen score was equivalent or with maximum gain of 1 point for 11 patients (87%) at 3 months. No intra-operative major complication was recorded. The median TAD was 16.4 mm (IQR 14.0-20.2) and lag screw position was in 85% of patients in the Cleveland central zone. Two patients needed revision surgery. Fracture union occurred in all patient.Conclusion The long Chimaera nailing device showed good functional and radiological outcomes.
Phenotypic similarity-based approach for variant prioritization for unsolved rare disease: a preliminary methodological report
Authors: Lebreton Emeline , Matalonga Leslie , Hongnat Oscar , Chahdil Maroua , Piscia Davide , Paramonov Ida , Ellwanger Kornelia , Kohler Sebastian , Robinson Peter , Graessner Holm , Beltran Sergi , Lucano Caterina , Hanauer Marc , Rath Ana , Lagorce David 
Published: June 2023

Abstract
Rare diseases (RD) have a prevalence of not more than 1/2000 in the European population, and are characterised by the difficulty of obtaining a correct and timely diagnosis. According to Orphanet, 72,5% of RD have a genetic origin although 35% of them do not yet have an identified causative gene. A significant proportion of patients suspected to have a genetic RD receive an inconclusive exome/genome sequencing. Working towards the International Rare Diseases Research Consortium (IRDiRC)’s goal for 2027 to ensure that all people living with a RD receive a diagnosis within one year of coming to medical attention, the Solve-RD project aims to identify the molecular causes underlying undiagnosed RD. As part of this strategy, we developed a phenotypic similarity-based variant prioritization methodology comparing submitted cases amongst them and with known RD in Orphanet. A 3-step programmatic cascade of phenotypic similarity calculations using The Human Phenotype Ontology (HPO), the Orphanet Rare Diseases Ontology (ORDO) and the HPO-ORDO Ontological Module (HOOM) was developed; genomics data reanalysis was performed by the RD-Connect Genome-Phenome Analysis Platform (GPAP). The methodology was tested in 4 exemplar cases, discussed with experts from European Reference Networks. Variants of interest (pathogenic or likely pathogenic) were detected in 8.8% of the 725 cases clustered by similarity algorithms, formulating diagnostic hypotheses that were validated in 42.1% of them and need further explorations in another 10.9%. Based on the promising results, we are devising an automated standardized phenotypic-based re-analysis pipeline to be applied to the entire unsolved cases cohort in Solve-RD.