bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do housing rental and sales markets incentivise energy-efficient retrofitting of western Germany’s post-war apartments? Challenges for property owners, tenants, and policymakers
Authors: Galvin Ray 
Published: March 2023

AbstractA post-World War 2 building boom in western Germany (the original Bundesrepublik) produced a cohort of some 8 million apartments, built in 1946–1979, that are relatively homogeneous in design and materials. On average, these apartments are very energy-inefficient, consuming around 147 kWh of heating energy per square meter of floor area per year (kWh/m2/y). Retrofitting them to about 50 kWh/m2/y is necessary to meet Germany’s climate goals. Considerable skill and infrastructure have developed to attempt to achieve this, but it is expensive. This study investigates whether sales and rental markets disincentivise property owners from retrofitting these apartments to high energy efficiency standards. Data from sales and rental advertisements in 2019–2021 in Germany’s largest online housing advertisement portal, Immoscout24, were used to estimate market sales and rental premiums for energy efficiency in these apartments. For property owners who retrofit apartments then sell them, sales premiums for energy efficiency generally fail to compensate for the retrofit costs, unless the renovation is subsidised. Meanwhile, for purchasers, the reduction in energy costs due to higher energy efficiency does not compensate for the higher purchase price. Likewise, for landlords/landladies who retrofit apartments then rent them out, the rental premiums due to higher energy efficiency are nowhere near sufficient to compensate for the retrofit costs. Tenants, however, can often offset the rental premium through energy savings. In all four cases, there is regional variation. Based on a detailed investigation of this market for energy efficiency, this study suggests specific policy interventions to compensate for these market anomalies.
Sich (Nicht‑)Einlassen auf Schule
Authors: Bollweg Petra 
Published: March 2023

ZusammenfassungDie Anwesenheit von Kindern und Jugendlichen in Schule und Unterricht ist eine gesellschaftliche Norm. Die Abwesenheit von Schüler-innen in der Schule wird als Schulabsentismus bezeichnet. Er verweist auf ein Phänomen, dem ein relativ hohes Potenzial von Vorannahmen und Scheingewissheiten anhaftet.
Metabolic interventions improve HBV envelope-specific T-cell responses in patients with chronic hepatitis B
Authors: Fu Yu-Long , Zhou Shuang-Nan , Hu Wei , Li Jing , Zhou Ming-Ju , Li Xiao-Yu , Wang You-Yuan , Zhang Peng , Chen Si-Yuan , Fan Xing , Song Jin-Wen , Jiao Yan-Mei , Xu Ruonan , Zhang Ji-Yuan , Zhen Cheng , Zhou Chun-Bao , Yuan Jin-Hong , Shi Ming , Wang Fu-Sheng , Zhang Chao 
Published: March 2023

Abstract
Background
Restoration of HBV-specific T cell immunity is a promising approach for the functional cure of chronic Hepatitis B (CHB), necessitating the development of valid assays to boost and monitor HBV-specific T cell responses in patients with CHB.

Methods
We analyzed hepatitis B virus (HBV) core- and envelope (env)-specific T cell responses using in vitro expanded peripheral blood mononuclear cells (PBMCs) from patients with CHB exhibiting different immunological phases, including immune tolerance (IT), immune activation (IA), inactive carrier (IC), and HBeAg-negative hepatitis (ENEG). Additionally, we evaluated the effects of metabolic interventions, including mitochondria-targeted antioxidants (MTA), polyphenolic compounds, and ACAT inhibitors (iACAT), on HBV-specific T-cell functionality.

Results
We found that HBV core- and env-specific T cell responses were finely coordinated and more profound in IC and ENEG than in the IT and IA stages. HBV env-specific T cells were more dysfunctional but prone to respond to metabolic interventions using MTA, iACAT, and polyphenolic compounds than HBV core-specific T-cells. The responsiveness of HBV env-specific T cells to metabolic interventions can be predicted by the eosinophil (EO) count and the coefficient of variation of red blood cell distribution width (RDW-CV).

Conclusion
These findings may provide valuable information for metabolically invigorating HBV-specific T-cells to treat CHB.

Graphical abstract
Reconciling control and identity development: experiences of South African adolescents
Authors: Naudé Luzelle , van Damme Elizabeth Cornelia 
Published: March 2023

AbstractThe aim of this study was to explore how a group of South African adolescents experience and react to being controlled during their process of finding a personal identity. Adolescents from the Eastern Cape province in South Africa (n = 120; 58.33% female) participated in focus group discussions regarding their experiences of how control shaped their sense of self. Participants understood identity as a continuous and fluid process of negotiation and adjustment shaped by significant others and embedded in social context. Participants articulated various experiences of control, mostly negative. Through thematic analysis, three pathways were constructed as distinct reactions to control: Conforming and Submitting, Finding Freedom, and Internalising. Each of these reactions contains a unique combination of exploration and commitment, with specific implications for identity development and achievement.
Changes in macrofaunal groups before, during and after the Cenomanian–Turonian biotic crisis in north Eastern Desert, Egypt
Authors: Abd-Elhameed Shahin , Salama Yasser , Mahmoud Abdelaziz 
Published: March 2023

AbstractThe stratigraphic distribution of the different faunal groups of the upper Cenomanian–lower Turonian deposits in the north Eastern Desert, Egypt, is investigated. Variations in species richness, faunal diversity, extinction and origination rates before, during, and after the globally known Oceanic Anoxic Event (OAE) 2 are documented. The OAE2 interval is constrained by the first occurrence of the marker ammonite species Vascoceras cauvini and the last occurrence of Vascoceras proprium, along with the positive δ13C excursions, previously identified from the Wadi El-Burga section. A prominent decline in species richness and diversity, high extinction rates, and low origination rates of the recorded macrofaunal elements are reported during the OAE2 interval. Such faunal bottleneck was attributed to the prevailing major palaeoclimatic and palaeoenvironmental perturbations during that time. Besides oceanic anoxia, changes in sea water palaeotemperature and sea level are discussed. It can be concluded that oceanic anoxia, warming, and /or transgressive episodes were the major driving mechanisms of the faunal crisis reported in the present work.
The biology of an isolated Mashona mole-rat population from southern Malawi, with implications for the diversity and biogeography of the genus Fukomys
Authors: Šumbera R. , Uhrová M. , Begall S. , Caspar K. R. , Jerkovičová D. , Van Daele P. , Chitaukali W. N. , Faulkes C. G. , Bennett N. C. , Johannes C. , Burda H. , Mikula O. 
Published: March 2023

AbstractThe Mashona mole-rat, Fukomys darlingi (Thomas, 1895), is a little studied social African mole-rat (Bathyergidae) from south-astern Africa. Here, we present an integrative study characterizing the genetic diversity of populations assigned to F. darlingi with special focus on animals from Nsanje, southern Malawi. These mole-rats show pronounced differences in body mass and general appearance compared to nominate F. darlingi from Zimbabwe and Mozambique, but their taxonomic status has so far remained unclear. A genetic analysis encompassing all major lineages of the genus Fukomys suggests that this population indeed represents a deeply nested lineage within the F. darlingi clade. The karyotype of the Nsanje mole-rats also corresponds to that of the nominate form, being 2n = 54. While both nuclear and mitochondrial data agree about the assignment of the Nsanje mole-rats to F. darlingi, our analyses revealed substantial mitonuclear discordance for other branches within the Fukomys phylogenetic tree. Nsanje mole-rats are significantly larger than nominate F. darlingi and their ontogeny and reproduction closely resemble similar-sized congeneric species rather than the nominate population. The somatic growth of the Nsanje form is the slowest of all African mole-rats. The maximum life span of F. darlingi is at least 19 years. The observed differences between nominate F. darlingi and mole-rats from Nsanje may be attributed mainly to their different body mass. Our study highlights the advantages of an integrative approach for understanding the diversity of African mole-rats and emphasizes the great intraspecific variability that may be encountered in these underground-dwelling rodents.
Flexitraits, Natural Chemical Tracers of Plant Competition and Productivity in Pacific Mangroves
Authors: Fry Brian , O’Mara Kaitlyn , Riekenberg Philip M. , Wassenaar Leonard I. , Cormier Nicole 
Published: March 2023

AbstractMetabolomic and genomic markers in plants have helped diagnose evolutionary pressures and resulting modern-day floristic diversification. Here we use a different set of metrics, 17 biochemical measures made at the whole tissue or bulk tissue level, to study diversification in resource use and productivity among Pacific mangroves. Three mangrove species Bruguiera gynmorhiza (BRGY), Rhizphora apiculata (RHAP), and Sonneratia alba (SOAL) were studied across 5 sites on the island of Kosrae, Federated States of Micronesia with measurements of the following chemical metrics: C, N, P, K, Na, Mg, Ca, B, S, Mn, Fe, Cu, Zn elements and isotope values δ2H, δ13C, δ15N, and δ34S. Species were remarkably distinct in chemical profiles, showing significant differences across all metrics. This indicated long-term resource use partitioning and optimization, with metrics showing physiology and patch-related differences. The patch-related differences meant that metrics were not really fixed in species, but represented flexible traits (“flexitraits”) in fingerprinting mangrove ecology. Effects of tree harvesting could be fingerprinted with the metrics at one of the Kosrae sites. Modeling showed two results. (1) Conservation efforts to preserve low-nutrient specialists like BRGY probably should involve removal of competing SOAL and RHAP rather than nutrient reductions. (2) Although mangrove growth rates were most limited by P, water was a strongly co-limiting factor. This study introduces a new physiological parameter to plant ecology, a water-to-phosphorus ratio, “normalized δ13C/P” or “f13C/P”, that should generally help diagnose how plant N and P nutrient use can be co-limited by water.
Role of ADAM33 short isoform as a tumor suppressor in the pathogenesis of thyroid cancer via oncogenic function disruption of full-length ADAM33
Authors: Lan Jing , Zhou Yehui , Liu Yang , Xia Yu , Wan Yuqiu , Cao Jianbo 
Published: March 2023

AbstractThyroid cancer is the most prevalent endocrine malignancy globally; however, its underlying pathogenesis remains unclarified. Reportedly, alternative splicing is involved in processes such as embryonic stem and precursor cell differentiation, cell lineage reprogramming, and epithelial-mesenchymal transitions. ADAM33-n, an alternative splicing isoform of ADAM33, encodes a small protein containing 138 amino acids of the N-terminal of full-length ADAM33, which constructs a chaperone-like domain that was previously reported to bind and block the proteolysis activity of ADAM33. In this study, we reported for the first time that ADAM33-n was downregulated in thyroid cancer. The results of cell counting kit-8 and colony formation assays showed that ectopic ADAM33-n in papillary thyroid cancer cell lines restricted cell proliferation and colony formation. Moreover, we demonstrated that ectopic ADAM33-n reversed the oncogenic function of full-length ADAM33 in cell growth and colony formation in the MDA-T32 and BCPAP cells. These findings indicate the tumor suppressor ability of ADAM33-n. Altogether, our study findings present a potential explanatory model of how the downregulation of the oncogenic gene ADAM33 promotes the pathogenesis of thyroid cancer.
Impact of microscopic extrathyroidal extension on differentiated thyroid cancer post-surgical risk of recurrence: a retrospective analysis
Authors: Patti L. , Gay S. , Musso L. , Maltese C. , Spina B. , Minuto M. , Morbelli S. , Vera L. , Boschetti M. , Ferone D. , Albertelli M. 
Published: March 2023

Abstract
Purpose
In the last edition of the American Joint Committee on Cancer (AJCC) staging system, differentiated thyroid cancers (DTC) showing microscopic extrathyroidal extension (mETE) are considered comparable to intrathyroidal cancers for their clinical behavior and prognosis. The aim of the study is to evaluate the impact of this updated assessment of T, when applied to the postoperative recurrence risk stratification, according to the American Thyroid Association Guidelines (ATA-RR).

Methods
One-hundred DTC patients who underwent total thyroidectomy were retrospectively evaluated. The downstaging of mETE was introduced in the definition of T, and the updated classification defined as modified ATA-RR (ATAm-RR). For each patient, post-surgical basal and stimulated thyroglobulin (Tg) levels, neck ultrasound (US) and post-ablative 131-I whole body scan (WBS) reports were considered. The predictive performance (PP) of disease recurrence was calculated both for each single parameter, as well as for all of them.

Results
According to ATAm-RR classification, 19/100 patients (19%) were downstaged. ATA-RR proved a significant PP for disease recurrence (DR) (sensitivity 75.0%, specificity 63.0%, p = 0.023). However, ATAm-RR performed slightly better due to an increased specificity (sensitivity 75.0%, specificity 83.7%, p < 0.001). For both classifications, the PP was optimal when all the above-mentioned predictive parameters were considered.

Conclusion
Our results suggest that the new assessment of T considering mETE resulted in a downgrading of ATA-RR class in a significant number of patients. This provides a better PP for disease recurrence, and the best PP was obtained when considering the whole predictive variables together.
Analysis and Experimental Research on Vibration Characteristics of Pressure Shell Structure
Authors: Su P. , Wu J. , Liu S. 
Published: March 2023

Abstract
The vibration and sound radiation characteristics of the submarine pressure hull structure are important performance indicators for the acoustic design of the submarine structure. In this paper, the spectral element method is used to analyze the vibration of the shell structure. Combined with the periodic structure theory, the theoretical calculation method of the periodic ribbed shell structure is deduced, and the analytical method that can be used to calculate the vibration of the pressure shell structure is established. The feasibility of applying the spectral element method to the vibration calculation of the pressure shell structure is verified by comparing the analytical calculation and the finite element simulation. The vibration characteristics test experiment of the actual submarine pressured hull structure is carried out. The results show that the theoretical analysis is correct.

Highlights
The vibration and sound radiation characteristics of the submarine pressure hull structure have an important influence on the radiated noise of the submarine.
A theoretical analysis method of vibration characteristics of pressure hulled based on spectral element method and periodic structure theory is proposed.
The experimental study on vibration characteristics and active control of line spectrum of the pressure hull is carried out.
Life of a Dalit magistrate: Ideologies and politics in Dalit life in North India, 1920–1954
Authors: Kumar Vijay 
Published: March 2023

AbstractThis article discusses Chaudhari Mulkiram (April 1910–August 1954) and the contesting ideologies, memories, histories, and socio-political conditions surrounding his career from the 1920s to the mid-1950s. Mulkiram belonged to the Dhangar, a sub-caste of the Khatik caste in Meerut. He was the first Dalit of the United Provinces (UP) who qualified for the Public Service Commission in 1939. This article shows his socio-religious and socio-political relations and responses to the Arya Samaj, Congress, and Scheduled Caste Federation. It reveals how the representatives of these agencies portrayed his life and work. This article also discusses how his relations and responses helped and influenced his caste members in the western UP. It argues that the Arya Samaj, Harijan Sevak Sangh, and Congress used the first generation of Dalit civil servants like Mulkiram to cultivate local leaders and to mobilize local Dalits, peasants, labourers, and villagers to act in their political interests against Ambedkar’s movement. Hence, in the 1940s and early 1950s, Mulkiram presented himself as a Gandhi bhakt, Jan Neta (public leader), and Sanyasi (household monk and socio-religious reformer).
Adaptation Strategies Strongly Reduce the Future Impacts of Climate Change on Simulated Crop Yields
Authors: Abramoff Rose Z. , Ciais Philippe , Zhu Peng , Hasegawa Toshihiro , Wakatsuki Hitomi , Makowski David 
Published: March 2023

AbstractSimulations of crop yield due to climate change vary widely between models, locations, species, management strategies, and Representative Concentration Pathways (RCPs). To understand how climate and adaptation affects yield change, we developed a meta‐model based on 8703 site‐level process‐model simulations of yield with different future adaptation strategies and climate scenarios for maize, rice, wheat and soybean. We tested 10 statistical models, including some machine learning models, to predict the percentage change in projected future yield relative to the baseline period (2000–2010) as a function of explanatory variables related to adaptation strategy and climate change. We used the best model to produce global maps of yield change for the RCP4.5 scenario and identify the most influential variables affecting yield change using Shapley additive explanations. For most locations, adaptation was the most influential factor determining the projected yield change for maize, rice and wheat. Without adaptation under RCP4.5, all crops are expected to experience average global yield losses of 6%–21%. Adaptation alleviates this average projected loss by 1–13 percentage points. Maize was most responsive to adaptive practices with a projected mean yield loss of −21% [range across locations: −63%, +3.7%] without adaptation and −7.5% [range: −46%, +13%] with adaptation. For maize and rice, irrigation method and cultivar choice were the adaptation types predicted to most prevent large yield losses, respectively. When adaptation practices are applied, some areas are predicted to experience yield gains, especially at northern high latitudes. These results reveal the critical importance of implementing adequate adaptation strategies to mitigate the impact of climate change on crop yields.
5‐Species MHD Study of Martian Proton Loss and Source
Authors: Sun Wenyi , Ma Yingjuan , Russell Christopher T. , Luhmann Janet , Nagy Andrew , Brain David 
Published: March 2023

AbstractAlthough photochemistry‐enabled escape of oxygen is a dominant atmospheric loss process at Mars today, ion outflow plays an essential role in the long‐term evolution of Mars' atmosphere. Apart from heavy planetary ions such as O+, O2+, and CO2+, the loss of planetary protons is also important because it could be related to water loss. To study planetary proton loss due to solar wind interaction, we improve the 4‐species (O+, O2+, CO2+, and H+) single‐fluid magnetohydrodynamic (MHD) model of Mars, to a 5‐species (separating planetary protons and solar wind protons) MHD model so that the two types of protons can be tracked separately. The global distributions of solar wind protons and planetary ions at low altitudes are investigated. The calculated planetary proton escape rates are larger than heavy ion loss rates and solar wind proton inflows for both solar maximum and minimum conditions. Planetary proton escape rates are 1–2 orders less than neutral hydrogen loss, suggesting that planetary protons could contribute to no >10% of the hydrogen loss under current conditions. By comparing normal cases with cases for which H‐O charge exchange reactions or electron impact ionizations are switched off, we find that H‐O charge exchange mainly affects densities at low altitudes, while impact ionizations exert great influence on escape rates at high altitudes. The overall results suggest the specific treatment of proton origins in models of Mars atmosphere escape provides better insight into the contributing processes, and should be included in future studies focusing on water's fate.
Prediction and Verification of Parker Solar Probe Solar Wind Sources at 13.3 R⊙
Authors: Badman S. T. , Riley P. , Jones S. I. , Kim T. K. , Allen R. C. , Arge C. N. , Bale S. D. , Henney C. J. , Kasper J. C. , Mostafavi P. , Pogorelov N. V. , Raouafi N. E. , Stevens M. L. , Verniero J. L. 
Published: March 2023

AbstractDrawing connections between heliospheric spacecraft and solar wind sources is a vital step in understanding the evolution of the solar corona into the solar wind and contextualizing in situ timeseries. Furthermore, making advanced predictions of this linkage for ongoing heliospheric missions, such as Parker Solar Probe (Parker), is necessary for achieving useful coordinated remote observations and maximizing scientific return. The general procedure for estimating such connectivity is straightforward (i.e., magnetic field line tracing in a coronal model) but validating the resulting estimates is difficult due to the lack of an independent ground truth and limited model constraints. In its most recent orbits, Parker has reached perihelia of 13.3R⊙ and moreover travels extremely fast prograde relative to the solar surface, covering over 120° longitude in 3 days. Here we present footpoint predictions and subsequent validation efforts for Parker Encounter 10, the first of the 13.3R⊙ orbits, which occurred in November 2021. We show that the longitudinal dependence of in situ plasma data from these novel orbits provides a powerful method of footpoint validation. With reference to other encounters, we also illustrate that the conditions under which source mapping is most accurate for near‐ecliptic spacecraft (such as Parker) occur when solar activity is low, but also require that the heliospheric current sheet is strongly warped by mid‐latitude or equatorial coronal holes. Lastly, we comment on the large‐scale coronal structure implied by the Encounter 10 mapping, highlighting an empirical equatorial cut of the Alfvèn surface consisting of localized protrusions above unipolar magnetic separatrices.