bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelvic morphologies of developmental dysplasia and primary osteoarthritis on range of motion after total hip arthroplasty
Authors: Funahashi Hiroto , Osawa Yusuke , Seki Taisuke , Takegami Yasuhiko , Nishida Kazuki , Imagama Shiro 
Published: March 2023

AbstractBony impingement, especially in the anterior inferior iliac spine (AIIS) after total hip arthroplasty (THA), may cause dislocation. However, the influence of AIIS characteristics on bony impingement after THA is not fully understood. Thus, we aimed to determine the morphological characteristics of AIIS with developmental dysplasia of the hip (DDH) and primary osteoarthritis (pOA) and to evaluate its effect on range of motion (ROM) after THA. Hips from 130 patients who underwent THA, including pOA were analyzed. In total, we had 27 male and 27 female participants with pOA, and 38 male and 38 female participants with DDH. The horizontal distances of AIIS from teardrop (TD) were compared. In the computed tomography simulation, flexion ROM was measured, and its relationship to the distance between TD and AIIS was investigated. DDH had a more medial (male: DDH, 36.9 ± 5.8; pOA, 45.5 ± 6.1; p < 0.001) (female: DDH, 31.5 ± 10.0; pOA, 36.2 ± 4.7; p < 0.001) position of AIIS than pOA. In the male with pOA group, flexion ROM was significantly smaller than that in the other groups, and there was a correlation between flexion ROM and horizontal distances (r = −0.543; 95% confidence interval = −0.765 to −0.206; p = 0.003). AIIS position is a factor that limits ROM during flexion after THA, particularly in males. Further studies are required to develop surgical strategies for cases of impingement at the AIIS site after THA. Level of evidence: Ш, retrospective comparative study.
Transient inhibition of meniscus cell migration following acute inflammatory challenge
Authors: Lemmon Elisabeth A. , Bonnevie Edward D. , Patel Jay M. , Miller Liane M. , Mauck Robert L. 
Published: March 2023

AbstractMeniscus tears represent a common orthopedic injury that often requires surgery to restore pain‐free function. The need for surgical intervention is due, in part, to the inflammatory and catabolic environment that inhibits meniscus healing after injury. In other organ systems, healing is dependent on the migration of cells to the site of injury; however, in the meniscus, it is currently unknown how the microenvironment dictates cell migration in the postinjury inflamed setting. Here, we investigated how inflammatory cytokines alter meniscal fibrochondrocyte (MFC) migration and sensation of microenvironmental stiffness. We further tested whether an FDA approved interleukin‐1 receptor antagonist (IL‐1Ra; Anakinra) could rescue migratory deficits caused by inflammatory challenge. When cultured in the presence of inflammatory cytokines (tumor necrosis factor‐α [TNF‐α] or interleukin‐1β [IL‐1β]) for 1 day, MFC migration was inhibited for 3 days before returning to control levels at Day 7. This migratory deficit was clear in three‐dimensional as well, where fewer MFCs exposed to inflammatory cytokines migrated from a living meniscal explant compared with control. Notably, addition of IL‐1Ra to MFCs previously exposed to IL‐1β restored migration to baseline levels. This study demonstrates that joint inflammation can have negative impacts on meniscus cell migration and mechanosensation, affecting their potential for repair, and that resolution of this inflammation with concurrent anti‐inflammatories can reverse these deficits. Future work will apply these findings to mitigate the negative consequences of joint inflammation and promote repair in a clinically relevant meniscus injury model.
Factors affecting the soil organic carbon pool in marshes along the Yarlung Zangbo River, Tibet, China
Authors: Zhang Zhongsheng , Zhang Xuehui , Xue Zhenshan , Wu Haitao 
Published: March 2023

AbstractMarshes in high plateaus are critical in governing carbon cycle because of their huge but labile soil organic carbon (SOC) storage, which of even a small proportion of carbon contained in SOC can lead to high variations in the atmospheric CO2 levels. The Yarlung Zangbo River (YZR) is the world's highest river, flowing from west to east across Tibet. There are widespread alpine marshes and meadows along the YZR basin, with huge SOC storage but extremely vulnerable to climate change. However, few studies were carried out to explore the potential effects of environmental factors on SOC pool along the YZR. In the present work, effects of climate, plant biomass, soil nutrients, and molecular features of organic matter on SOC storage were systematically evaluated. Results indicated that SOC contents varied from 0.86% to 29.68%, with an average of 7.29%, and an estimated 5887 Gg (109g) of carbon was stored in marsh soils along the YZR. Soil accretion rates ranged from 1.66 to 2.73 mm yr−1, while carbon sequestration rates ranged from 43.65 gC m−2 yr−1 to 125.4 gC m−2 yr−1, with an average of 75.89 gC m−2 yr−1. It was estimated that 34.58 Gg of carbon was sequestrated by wetlands along the YZR every year. The abundance of lignin‐derived components, total nitrogen, and soil moisture contents (SWC) were the main drivers promoting SOC contents. SOC storage was significantly related to mean annual temperature (Temp) but decreased with the ratio of annual precipitation (Pre) to Temp. Compared with the chemical decomposition resistance of organic matter, more SOC variations arose from climate, and climate warming had adverse impacts on SOC pool. SWC were proved to be the most powerful promoter of SOC increase. Rising temperatures are expected to have a detrimental impact on SOC storage when the climate is warming in the future.
Restoration of agroecosystems with conservation agriculture for food security to achievesustainabledevelopment goals
Authors: Kumawat Anita , Yadav Devideen , Srivastava Pankaj , Babu Subhash , Kumar Dinesh , Singh Deepak , Vishwakarma Dinesh Kumar , Sharma V. K. , Madhu M. 
Published: March 2023

AbstractCurrently, agroecosystems sustainability is mainly challenged by unsustainable agricultural practices that lead to land degradation and amplified climate change. About 25% of the World's total land area has deteriorated due to improper agricultural land management, resulting in ~24 billion tonnes of annual soil loss. Globally, soil erosion, mainly caused by high‐frequency tilling, crop residue removal or burning, poor pasture management, and inefficient crop rotations, is responsible for >40% of total land deterioration problems. Conservation agriculture (CA) seeks minimum soil disturbance, permanent soil cover, and crop rotation, which are indispensable for soil fertility restoration, carbon stabilization, increased soil biodiversity, and sustainable food production. In the last decades, the global annual adoption rate of CA was 7 M ha yr−1. CA‐based soil and crop management practices enhanced water productivity, soil organic carbon, crop productivity, and energy use efficiency by 18%–66%, 12%–93%, 3.8%–76.2%, and 8.9%–40.2%, respectively, over conventional practices under diverse agroecosystems in India. Hence, adopting CA can avert/minimize the problem of land degradation and food insecurity by improving crop productivity and decreasing soil erosion, energy use, and carbon emission, besides maintaining soil physicochemical and biological health. Moreover, CA can be a sustainable way to ensure global food demand, achieve sustainable development goals (SDGs), and restore soil health, and multiple agroecosystem services. This study aims to provide in‐depth insights into the role of CA in restoring agroecosystem services, attaining SDGs, and ensuring global food security.
A comparison and coupling of two novel sensors for intertidal bed‐level dynamics observation
Authors: Xu Tianping , Hu Zhan , Gong Wenping , Willemsen Pim W. J. M. , Borsje Bas W. , van Hespen Rosanna , Bouma Tjeerd J. 
Published: March 2023

AbstractPrevious studies have revealed the importance of short‐term bed‐level change on the long‐term development of intertidal ecosystems. One of the recent advancements in the short‐term bed dynamics observation is the developments of laser‐based surface elevation dynamics (LSED) and acoustic surface elevation dynamics (ASED) sensors. These two sensors are developed to automatically monitor tidally induced bed‐level changes, and their measuring windows are during emergent and submerged periods, respectively. So far, there is no direct comparison or joint application of these two sensors. Therefore, in the current study, we first compare their observation precision in both laboratory and field conditions. Results show that both sensors' measurements are in good agreement with the manual measurements in the flume (R2 > 0.99) and field (R2 ≈ 0.70), indicating the applicability of each sensor in natural environment. Finally, a coupled system (i.e., combining LSED and ASED) is established in a mangrove wetland and both sensors show good agreement with each other (R2 = 0.69). Results also demonstrate that the coupled observation system can well capture the bed‐level change during emergent and submerged conditions, which provides detailed continuous data sets to study the bed‐level dynamics within a tidal cycle. Furthermore, large‐scale monitoring systems can also be established via mobile network module embedded in the sensor, providing real‐time monitoring for bed‐level changes, which is valuable to coastal morphological research and vital for detecting deterioration of coastal ecosystems and the services they provide to be able to apply adaptive management.
From warrior to guardian: An autoethnographic study of how consumers think about and interact with the natural world
Authors: Hannah David , Ferreira Caitlin , Pitt Leyland 
Published: March 2023

AbstractConsumers are increasingly concerned about how their interactions with the natural world affect both the health of that environment, and their own well‐being and enjoyment of life. More aware consumers seek to make sense of the natural world around them and consider how their consumer behavior impacts this environment. How actors notice and bracket ecologically material cues from a stream of experience and build connections and causal networks between these has been referred to as ecological sensemaking. This research examines ecological sensemaking in a specific context, that being in the experience of catch‐and‐release fishing. Data were gathered through a process of autoethnographic inquiry obtained over the course of four fishing trips. The results reflect the process of ecological sensemaking pertaining to the experience. Through the findings, we propose a new concept, ecological reasoning, which seeks to provide a critical link between ecological sensemaking and ecological embeddedness. Using this new concept, the research contributes to extant understanding of how consumers think about and interact with the natural world. Apart from constructing an overarching narrative of the experience, four subnarratives are also identified, in a chronological sequence that comprises the entire experience of catch‐and‐release fishing. The findings have implications for the broader management and marketing disciplines seeking to establish better ways of interacting with the natural world, both for themselves and their consumers.
Single breath‐hold CINE imaging with combined simultaneous multislice and region‐optimized virtual coils
Authors: Kim Daeun , Coll‐Font Jaume , Lobos Rodrigo A. , Stäb Daniel , Pang Jianing , Foster Anna , Garrett Thomas , Bi Xiaoming , Speier Peter , Haldar Justin P. , Nguyen Christopher 
Published: March 2023

PurposeTo investigate the feasibility of combining simultaneous multislice (SMS) and region‐optimized virtual coils (ROVir) for single breath‐hold CINE imaging.MethodROVir is a recent virtual coil approach that allows reduced‐field of view (FOV) imaging by localizing the signal from a region‐of‐interest (ROI) and/or suppressing the signal from unwanted spatial regions. In this work, ROVir is used for reduced‐FOV SMS bSSFP CINE imaging, which enables whole heart CINE with a single breath‐hold acquisition.ResultsReduced‐FOV CINE with either SMS‐only or ROVir‐only resulted in significant aliasing, with severely reduced image quality when compared to the full FOV reference CINE, while the visual appearance of aliasing was substantially reduced with the proposed SMS+ROVir. The end diastolic volume, end systolic volume, and ejection fraction obtained using the proposed approach were similar to the clinical reference (correlations of 0.92, 0.94, and 0.88, respectively with in each case, and biases of 0.1, 1.6 mL, and , respectively). No statistically significant differences for these parameters were found with a Wilcoxon rank test (p = 0.96, 0.20, and 0.40, respectively).ConclusionWe demonstrated that reduced‐FOV CINE imaging with SMS+ROVir enables single breath‐hold whole‐heart imaging without compromising visual image quality or quantitative cardiac function parameters.
Efficacy of Florfenicol and Oxytetracycline Administered in Feed to Control Cisco Mortality Associated with Aeromonas salmonicida Infections
Authors: Cupp Aaron R. , Tuttle-Lau Maren T. , Leis Eric , Wolfe Samantha L. , Smerud Justin R. , Oliver John W. , Erickson Richard A. , Hannah Austin P. , Johnson Aaron E. , Nelson Rachel G. , Standish Isaac , Wils Joel M. , Gaikowski Mark P. 
Published: March 2023

Abstract
Two medications (one with florfenicol and one with oxytetracycline) that are approved in the United States to control mortality due to furunculosis associated with Aeromonas salmonicida were assessed to determine their efficacy in medicated feeds to treat A. salmonicida-infected Cisco (also known as Lake Herring) Coregonus artedi. Cisco were subjected to static infection baths containing A. salmonicida or a sham control and then were distributed to replicate test tanks within four treatment groups: (1) fish infected with A. salmonicida and treated with 15 mg florfenicol·kg body weight (BW)−1·d−1, (2) fish infected with A. salmonicida and treated with 83 mg oxytetracycline·kg BW−1·d−1, (3) fish infected with A. salmonicida and treated with a nonmedicated control feed, and (4) uninfected fish treated with a nonmedicated control feed. Medicated and comparative nonmedicated feed rations were administered at 2% BW/d for 10 consecutive days in accordance with the U.S. Food and Drug Administration-approved drug label, followed by a 7-d postdosing observation period using only nonmedicated feed. Cisco that were infected with A. salmonicida and treated with florfenicol (79% survival) and oxytetracycline (85% survival) had significantly higher survival than A. salmonicida-infected fish that received no medicated treatment (3% survival). No statistical difference in Cisco survival between the two medicated feed types was found. Aeromonas salmonicida was not detected in the kidney tissue of any surviving fish treated with medicated feeds at 7 d postdosing using quantitative PCR analysis. Overall, this study demonstrated that florfenicol- and oxytetracycline-medicated feeds were effective A. salmonicida treatments for Cisco. Outcomes may inform ongoing propagation efforts for Cisco restoration within the Great Lakes basin.
Application of a nurse‐led transitional care programme for patients discharged with T‐tubes after biliary surgery
Authors: Wang Meng , Hua Jieyu , Liu Yanli , Liu Tao , Liang Hongyin 
Published: March 2023

AbstractAimNurse‐led transitional care programmes (TCPs) have been shown to facilitate patient recovery in several illness settings, but its role among patients discharged with T‐tubes remains uncertain. The aim of the study was to investigate the effects of a nurse‐led TCP among patients discharged with T‐tubes.DesignThis retrospective cohort study was conducted at a tertiary medical centre.MethodsFrom January 2018 to December 2020, a total of 706 patients discharged with T‐tubes after biliary surgery were included in the study. Patients were divided into a TCP group (n = 255) and a control group (n = 451) based on whether they participated in a TCP. The baseline characteristics, discharge readiness, self‐care ability, transitional care quality and quality of life (QoL) were compared between the groups.ResultsSelf‐care ability and transitional care quality were significantly higher in the TCP group. Patients in the TCP group also exhibited improved QoL and satisfaction. The results suggest that the incorporation of a nurse‐led TCP among patients discharged with T‐tubes after biliary surgery is feasible and effective.No Patient or Public Contribution.
Ultrasound‐guided injection of the elbow: Cadaveric description for the proximal to distal approach
Authors: Ricci Vincenzo , Mezian Kamal , Chang Ke‐Vin , Mittal Nimish , Kara Murat , Naňka Ondřej , Özçakar Levent 
Published: March 2023

AbstractBackgroundUltrasound (US) guided intra‐articular elbow injections are commonly performed in clinical practice.ObjectiveTo describe a proximal to distal approach for US‐guided intra‐articular elbow injection.DesignCadaveric study.SettingsAcademic institution.MethodsBoth elbows of a single cadaver were injected with green‐colored water‐diluted latex dye using the US‐guided proximal to distal approach. In the left elbow, the needle was kept in situ; in the right elbow, the needle was removed. Subsequently, a layer‐by‐layer anatomical dissection was performed in both elbows.Main Outcome MeasuresPresence and distribution of the latex dye and location of the needle tip within the elbow joint capsule.ResultsAnatomical dissection of both elbows confirmed the correct intra‐articular position of the needle tip in the left elbow as well as correct placement of the latex dye bilaterally. During layer‐by‐layer dissection of the left elbow, the position of the radial nerve was observed anterior to the needle.ConclusionsThis cadaveric observation demonstrated that the US‐guided proximal to distal approach is a convenient technique to access the elbow joint. Compared to the previously described techniques, the in‐plane, proximal to distal approach may provide excellent needle visibility during the entire procedure, precisely targeting the articular space. The preliminary data need to be validated in additional clinical studies.
Computational study of the atmospheric oxidation and global warming potential of thionyl fluoride
Authors: Gao Keli , Hou Hua , Zhang Mi , Zhou Wenjun , Wang Baoshan 
Published: March 2023

AbstractThionyl fluoride (SOF2) is the dominant decomposition by‐product in SF6 under electrical discharges and a novel fluorinating reagent for organic synthesis to replace sulfuryl fluoride (SO2F2). Since both SF6 and SO2F2 are strong green‐house gases, for the sake of environmental concern, tropospheric oxidation of SOF2 by OH radicals in the presence of O2 has been investigated using various computational methods including density functional M06‐2X, coupled‐cluster (CCSD), the explicitly correlated RCCSD(T)‐F12, Gaussian‐4, ROCBS‐QB3, and Weizmann‐1 theories. The SO bond association between SOF2 and OH proceeds via the barriers of 1–3 kcal/mol to form various shallow wells HOSOF2 (−3 to −8 kcal/mol) linked by Berry pseudorotations and followed by HF‐elimination. Interception of the HOSOF2 adducts by O2 produce HO2 and SO2F2 predominantly via the concerted SO bond association/dissociation and proton‐transfer. The atmospheric lifetime and radiative efficiency for SOF2 were calculated to be 1.2–1.5 years and 0.223 W/m2/ppb, respectively. The global warming potential of SOF2 was estimated to be 169–211, as indicative of an eco‐friendly gas. However, the environmental impact of SOF2 should take into account the production of SO2F2 and HO2 due to oxidation.
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells
Authors: Louisse Jochem , Fragki Styliani , Rijkers Deborah , Janssen Aafke , van Dijk Bas , Leenders Liz , Staats Martijn , Bokkers Bas , Zeilmaker Marco , Piersma Aldert , Luijten Mirjam , Hoogenboom Ron , Peijnenburg Ad 
Published: March 2023

AbstractPer- and polyfluoroalkyl substances (PFASs) are omnipresent and have been shown to induce a wide range of adverse health effects, including hepatotoxicity, developmental toxicity, and immunotoxicity. The aim of the present work was to assess whether human HepaRG liver cells can be used to obtain insight into differences in hepatotoxic potencies of a series of PFASs. Therefore, the effects of 18 PFASs on cellular triglyceride accumulation (AdipoRed assay) and gene expression (DNA microarray for PFOS and RT-qPCR for all 18 PFASs) were studied in HepaRG cells. BMDExpress analysis of the PFOS microarray data indicated that various cellular processes were affected at the gene expression level. From these data, ten genes were selected to assess the concentration–effect relationship of all 18 PFASs using RT-qPCR analysis. The AdipoRed data and the RT-qPCR data were used for the derivation of in vitro relative potencies using PROAST analysis. In vitro relative potency factors (RPFs) could be obtained for 8 PFASs (including index chemical PFOA) based on the AdipoRed data, whereas for the selected genes, in vitro RPFs could be obtained for 11–18 PFASs (including index chemical PFOA). For the readoutOAT5expression, in vitro RPFs were obtained for all PFASs. In vitro RPFs were found to correlate in general well with each other (Spearman correlation) except for the PPAR target genesANGPTL4andPDK4. Comparison of in vitro RPFs with RPFs obtained from in vivo studies in rats indicate that best correlations (Spearman correlation) were obtained for in vitro RPFs based onOAT5andCXCL10expression changes and external in vivo RPFs. HFPO-TA was found to be the most potent PFAS tested, being around tenfold more potent than PFOA. Altogether, it may be concluded that the HepaRG model may provide relevant data to provide insight into which PFASs are relevant regarding their hepatotoxic effects and that it can be applied as a screening tool to prioritize other PFASs for further hazard and risk assessment.
A Meta‐Analysis of Endoscopic Stenting Versus Surgical Treatment for Malignant Gastric Outlet Obstruction
Authors: Del Nero Lorenzo , Sheijani Afscin Djahandideh , De Ceglie Antonella , Bruzzone Marco , Ceppi Marcello , Filiberti Rosa Angela , Siersema Peter , Conio Massimo 
Published: March 2023

AbstractBackground and AimSurgical gastrojejunostomy (GJJ) and endoscopic stenting (ES) are the two most available treatments for palliation of malignant gastric obstruction (MGOO). The aim of this study is to compare these two techniques regarding efficacy, safety, time of hospitalization and survival.MethodsWe performed a literature search from January 2010 to September 2020 to identify available randomized controlled studies and observational studies that compared ES and GJJ for the treatment of MGOO.ResultsA total of 17 studies were found. ES and GJJ showed similar technical and clinical success rate. ES was superior to obtain early oral re‐feeding, shorter length of hospitalization and a lower incidence of complications than GJJ. Surgical palliation had a lower recurrence rate of obstructive symptoms and longer overall survival than ES.ConclusionsBoth procedures have advantages and disadvantages. Probably we should not find the best palliation but the best approach based on the patient characteristics and tumor type.