bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of anthropomorphic computational phantoms at the UFPE
Authors: Vieira José Wilson , Andrade Pedro Henrique Avelino , Oliveira Alex Cristóvão Holanda , Lima Vanildo Júnior de Melo , Lacerda Isabelle Viviane Batista , Silva Arykerne Casado , Santana Ivan Eufrázio , Farias Whoody Alem Wanderley , Santos Larissa Cristina Silva , Oliveira Fernanda Gonçalves , Lima Fernando Roberto de Andrade 
Published: March 2023

To evaluate the amount of energy deposited in radiosensitive organs and tissues of the human body, when an anthropomorphic phantom is irradiated, researchers in numerical dosimetry use the so-called exposure computational models (ECMs). One can imagine an ECM as a virtual scene composed of a phantom in a mathematically defined position in relation to a radioactive source. The source in these ECMs produces the initial state of the simulation: the position, direction, and energy with which each particle enters the phantom are essential variables. For subsequent states of a particle history, robust Monte Carlo (MC) codes are used. For the subsequent states of a particle's history, robust Monte Carlo (MC) codes are used, which simulate the average free path that the particle performs without interacting, its interaction with the atoms in the medium and the amount of energy deposited per interaction. MC codes also evaluate normalization quantities, so the results are printed in text files in the form of conversion coefficients between the absorbed dose and the selected normalization quantity. From the 2000s, the authors have published ECMs where a voxel phantom is irradiated by photons in the environment of the MC code EGSnrc (EGS = Electron Gamma Shower; nrc = National Research Council Canada). The production of articles, dissertations and theses required the use of specific computational tools, such as the FANTOMAS, DIP (Digital Image Processing) and Monte Carlo applications, for the various steps of numerical dosimetry, which ranges from the preparation of input files to the execution from the ECM to the organization and graphical and numerical analysis of the results. This article reviews computational phantoms for dosimetry mainly those produced in DEN-UFPE dissertations and thesis.
Construction and functional analysis of nattokinase-producing cucumber obtained by the CRISPR-Cas9 system
Authors: Ni Z.Z. , Li J.T. , Zhang S.M. , Dong Y.W. , Liu Q.Q. , Li M.G. , Wang Y.N. 
Published: March 2023

AbstractNattokinase (NK) is effective in the prevention and treatment of cardiovascular disease. Cucumber is rich in nutrients with low sugar content and is safe for consumption. The aim of this study was to construct a therapeutic cucumber that can express NK, which can prevent and alleviate cardiovascular diseases by consumption. Because the Bitter fruit (Bt) gene contributes to bitter taste but has no obvious effect on the growth and development of cucumber, so the NK-producing cucumber was constructed by replacing the Bt gene with NK by using CRISPR/Cas9. The pZHY988-Cas9-sgRNA and pX6-LHA-U6-NK-T-RHA vectors were constructed and transformed into Agrobacterium tumefaciens EHA105, which was transformed into cucumber by floral dip method. The crude extract of NK-producing cucumber had significant thrombolytic activity in vitro. In addition, treatment with the crude extract significantly delayed thrombus tail appearance, and the thrombin time of mice was much longer than that of normal mice. The degrees of coagulation and blood viscosity as well as hemorheological properties improved significantly after crude extract treatment. These findings show that NK-producing cucumber can effectively alleviate thrombosis and improve blood biochemical parameters, providing a new direction for diet therapy against cardiovascular diseases.
An advanced perceptual U-Net segmentation based DDO-SDN classification system for lung pulmonary cancer detection
Authors: Thangavel Chitra , Palanichamy Jaganathan , Chinnasamy Sundar 
Published: March 2023

AbstractDeveloping an automated lung disease diagnosis framework is still remains one of the most challenging and demanding tasks in recent days. Most of the medical experts highly preferring the Computed Tomography (CT) lung images for an accurate disease detection. For this purpose, various segmentation, optimization, and classification techniques are developed in the conventional works for lung pulmonary disease detection. However, the existing techniques have the major problems of over segmentation, inaccurate ROI extraction, reduced accuracy, computational complexity, and high false positives. Thus, this research work intends to a simple and efficient segmentation based classification framework for an accurate lung nodules detection and pulmonary disease classification. Here, the tanh normalization technique is applied for preprocessing the input lung CT image with reduced noise and increased quality. After that, the perceptual U-Net segmentation algorithm is employed to accurately segment the lung nodules from the preprocessed CT images with simple computational operations. Moreover, the Decked Dragonfly Optimization (DDO) technique is used for choosing the relevant features based on the best optimal solution, which supports to obtain an increased detection accuracy and reduced classification error rate. Finally, the Speculative Deceptive Network (SDN) based classification algorithm is deployed to exactly detect the pulmonary lung cancer according to the optimal features. During evaluation, the performance of the proposed segmentation based DDO-SDN mechanism is validated and compared by using various evaluation parameters.
Trallero, C. (2020). El cálido abrazo de la música. Kit-book Servicios Editoriales.
Authors: Faure-Carvallo Adrien , Navarro-Calafell Mercè 
Published: March 2023

Ressenya de: Trallero, C. (2020). El cálido abrazo de la música. Kit-book Servicios Editoriales.
La càlida abraçada de la música.
Production of enriched cakes by apple pulp and peel powder and evaluation of chemical, functional and textural properties
Authors: Hosseini Ahmadreza , Pazhouhandeh Fahimeh 
Published: March 2023

Background: Apple pomace is a by-product of the fruit juice industry and comprises peel, seed, stem, and pulp tissues. This by-product contains dietary fiber, polyphenols, vitamins, and organic acids that can benefit human health and have a high potential as a dietary source. Baked products are well-known food types to humans and have a key role in feeding people worldwide. Nowadays, enriched products such as bread, cakes, and biscuits are available in stores. Different studies worldwide have been done about applying fruit juice industry by-products in the bakery.
Objective: This research aimed to evaluate apple peel (APE) and pulp (APU) powders separately as a partial substitute for wheat flour in cake production.
Methods: Apple peels and pulp, separately produced as residual wastes of juicing, were dried for 3 hours in the oven (60°C). The dried pulp and peel were ground and sieved using a 60 µm mesh. In this research, chemical and physic-chemical analyses were performed according to AACC (Approved Methods of the American Association of Cereal Chemists) and standard food analysis methods. Textural characteristic was analyzed by a texture analyzer (Brookfield CT3-10 Kg, US) equipped with an aluminum probe.
Results: Different levels of APE and APU powders (10, 20, and 30 %) were used to enrich the cakes. Wheat flour’s ash, fat, water, and oil absorption capacity were lower than APU and APE, whereas the moisture, protein, bulk density, and pH showed a reverse trend. Adding APU and APP to the cake formula increased total dietary fiber (TDF) from 4.14 % in the control sample to 27.71 % in the sample with 30 % apple peel powder (APE-30). The highest a* colorimetric parameter (redness) in the cake core was 3.82 in the APE-30 sample. The addition of APE and APU significantly increased the hardness, gumminess, and chewiness of the samples (p<0.05). APE-10 samples could improve the nutritional properties of the cakes without significant reduction (p>0.05) in overall acceptance compared to the control sample.
Conclusion: The results of this research demonstrated that a partial replacement of wheat flour with apple pulp and peel significantly increased the dietary fiber, especially insoluble fiber, compared to the control sample. Apple pulp powder and apple peel powder have the potential for use in cake making as a good source of dietary fiber.
The Pattern of Intraocular Pressure After Phacoemulsification Surgery In Senile Cataract
Authors: Meida Nur Shani , Ikliluddin Ahmad , Setyandriana Yunani , Rahmawati Vania 
Published: March 2023

Phacoemulsification is a surgical procedure for cataracts, which can increase intraocular pressure (IOP) and cause blindness due to glaucoma. It was known that the pattern of IOP changes after phacoemulsification surgery in senile cataracts. This study was an observational analytic study without a control group design. The study population was male and female senile cataract patients over 40 years of age who underwent phacoemulsification surgery at Kebumen Eye Centre Clinic in 2020. Intraocular pressure measurements using a Noncontact Tonometry by a nurse were carried out before surgery (D-0) and postoperatively on day 2 (D-2), day 9 (D-9), day 16 (D-16), and day- 23 (D-23). The data were analyzed using the Friedman test followed by the Post Hoc LSD test. The Friedman test results showed significant differences (p 0.05) in the IOP measurement at D-0, D-2, D-9, D-16, and D-23. Wilcoxon post hoc test showed IOP measurements on D-2 increased and then decreased normally. There was a change in the IOP pattern after phacoemulsification surgery, in which the IOP increased significantly on D-2 and then decreased normally.
Antimicrobial Activity of Pecut Kuda Leaf Extract (Stachytarpheta jamaicensis (L. Vahl) against Mycobacterium smegmatis
Authors: Ramadhani Putri Nadia , Kurniati Ika Dyah , Rakhmawatie Maya Dian 
Published: March 2023

Mycobacterium smegmatis infrequently causes infection, but it is easy to be pathogenic in immunosuppressed patients. Many reported that M. smegmatis resistance to several antibiotics became an impetus for searching for new antimicrobials. Therefore, this study aims to prove the effect of Pecut Kuda leaf extract (Stachytarpheta jamaicensis (L.) Vahl) on the growth of M. smegmatis mc2 155. This research is an experimental study with a post-test control group design. The susceptibility test was carried out using the two-fold microdilution method and resazurin staining. The concentration of Pecut Kuda leaf ethanol extract was prepared in the concentration range of 10000.0 – 625.0 µg/ml. Phytochemical analysis of the content of saponins, tannins, flavonoids, and alkaloids was also carried out on Pecut Kuda leaf ethanol extract. Pecut Kuda leaf ethanol extract can inhibit the growth of M. smegmatis with a minimum inhibitory concentration (MIC) of 5000 µg/ml (very weak activity) because, at the highest concentration of 10000 µg/ml, M. smegmatis still cannot be killed. Furthermore, Pecut Kuda leaf ethanol extract contains saponins, tannins, flavonoids, and alkaloids which are known to have antibacterial activity. However, further evaluation is needed to maximize the antibacterial activity of Pecut Kuda leaf extract, for example, by fractionating the extract.
Comparative evaluation of the clinical performance of supraglottic airways- Supreme laryngeal mask airway, I gel and baska mask
Authors: Phalgune Deepak , Cherian Lilly , Thatte Janhavi , Mahadik Shripad 
Published: March 2023

There are no studies comparing Supreme laryngeal mask airway (LMA), I gel and Baska mask in Indian population. A comparison of the clinical performance of Supreme LMA, I gel and Baska mask was undertaken in this randomized controlled study.The present research was undertaken in 75 patients aged 18 to 60 years who underwent elective surgery for less than 3-hour duration under general anaesthesia. The patients were randomly divided into three groups; Supreme LMA, I gel, and Baska mask. The oropharyngeal leak pressure (OLP) after 30 minutes to loss of spontaneous respiration was the primary objective, whereas the secondary objectives were attempts required for insertion of LMA, ease of gastric tube insertion, time required for gastric tube insertion and post-operative morbidity. The mean OLP of Baska mask group was (28.2 cm HO) as compared to Supreme LMA (25.3 cm HO) and I-gel (24.1 cm HO) groups (p-value = 0.0001). The mean gastric tube insertion time of Baska mask group was (20.7 s) as compared to Supreme LMA (6.7 s) and I-gel (9.6 s) groups (p-value = 0.0001). The three groups were comparable with regards to the number of attempts required, ease of gastric tube insertion and post-operative morbidity.A higher OLP was observed in Baska mass group as compared to Supreme LMA and I-gel. The three devices were similar in terms of attempts required for insertion, ease of gastric tube insertion and post-operative morbidity.
Anaesthetic challenges faced in a child with Morquio syndrome- An orphan disease
Authors: Ahmed Tasneem Fathima , Krishnan S Navaneetha , Ramakrishnan Lakshmi 
Published: March 2023

: Morquio syndrome is a progressive lysosomal storage disorder leading to accumulation of glycosaminoglycans in the soft tissue, cartilage, and bone causing skeletal dysplasia. : We present a four-year-old child diagnosed with right side inguinal hernia posted for herniotomy. He had a large head with short neck and kyphoscoliosis. Pre-operative MRI whole spine shows a hypoplastic dens causing canal stenosis, indenting the cord at C1 level. General Anesthesia was planned. With a video laryngoscope on standy by, patient was induced after stabilizing the neck with a custom neck collar and the airway was secured with a Proseal Laryngeal Mask Airway.: The airway management can be challenging because of accumulation of mucopolysaccharides in the soft tissue of upper airway and limited mouth opening due to involvement of temporo mandibular joints. A thorough pre-operative evaluation of airway must be done and a well planned anaesthetic technique must be executed.
The restaurant business model as a multidimensional construct supporting the management of the food service industry enterprise
Authors: Dereń Anna 
Published: March 2023

Purpose of the study: This article discusses the concept of a business model. Various concepts are presented to define this research object.
Methodology: The survey was conducted on a group of restaurants from Krakow. The study allowed us to identify three business models.
Main findings: It has been shown that there is no unanimity among researchers, not only as to what a business model is (a plan, a tool, a description of a system) but also as to its components. By characterizing the universal types of business models, with particular emphasis on the nature of restaurant business models, it was shown that the model should be best adapted to the specifications of the sector and the objectives of the company, and also the components may differ concerning the other sectors' business models and concerning the other sectors' business models. The business model is directly related to management strategy, so it should be a plan providing the best possible operation of the company that allows it to be competitive in the field.
Application of the study: A realistic depiction of the restaurant business model diversity.
Originality/Novelty of the study: The work combines theoretical and practical approaches to the topic of business models with a particular focus on the gastronomy industry.
LAK of Direction
Authors: Motz Benjamin A. , Bergner Yoav , Brooks Christopher A. , Gladden Anna , Gray Geraldine , Lang Charles , Li Warren , Marmolejo-Ramos Fernando , Quick Joshua D. 
Published: March 2023

Learning analytics defines itself with a focus on data from learners and learning environments, with corresponding goals of understanding and optimizing student learning. In this regard, learning analytics research, ideally, should be characterized by studies that make use of data from learners engaged in education systems, should measure student learning, and should make efforts to intervene and improve these learning environments. However, a common concern among members of the learning analytics research community is that these standards are not being met. In two analysis waves, we review a large and comprehensive sample of research articles from the proceedings of the three most recent Learning Analytics and Knowledge conferences, the premier conference venue for learning analytics research, and from articles published during the same time in the Journal of Learning Analytics (over the years of 2020, 2021, and 2022). We find that 37.4% of articles do not analyze data from learners in an education system, 71.1% do not include any measure of learning, and 89.0% of articles do not attempt to intervene in the learning environment. We contrast these findings with the stated definition of learning analytics and infer, like others before us, that scholarship in learning analytics research presently lacks clear direction toward its stated goals. We invite critical discussion of these findings from the learning analytics community, through open peer commentary.
Potential Dermatological Effects of Climate Change in Africa
Authors: Pillay L , Sema-Ramashala AR , Jessop S , Raboobee N , Lehloenya R , Moosa L , Mosam A 
Published: March 2023

Abstract
Climate change represents a major existential threat facing the global community, and it has already begun to affect human health in a multitude of ways. This article highlights and discusses the implications that climate change has already had and is expected to have for dermatologists.
A number of conditions are affected by climate changes. The distribution and frequencies of infections have altered due to changes in the causative organisms. Inflammatory conditions like atopic dermatitis have been exacerbated and the raised temperatures will also worsen the effects of ultraviolet radiation. Extreme weather events that result from climate change are followed by an array of dermatologic conditions that may be unusual for the given location. Dermatologists should be prepared to manage these potentially unfamiliar dermatologic consequences of climate change.
PERLINDUNGAN HUKUM TERHADAP PENGUPAHAN MENURUT UNDANG-UNDANG NOMOR 13 TAHUN 2003 TENTANG KETENAGAKERJAAN PADA PT. TANDAN ABADI MANDIRI KABUPATEN SAROLANGUN JAMBI
Authors: Salsabila Adinda tahlia , Antasari RR rina , Marzuki Marzuki 
Published: March 2023

ABSTRAK

Upah atau gaji adalah hak pemenuhan ekonomi bagi pekerja yang menjadi kewajiban dan tidak boleh diabaikan oleh para pihak yang mempekerjakan. Islam menekankan perlunya keadilan dalam segala hal, salah satunya mengenai pemberian gaji/upah kepada pekerja. Seperti yang terjadi di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi. Dimana upah yang diberikan sesekali mengalami keterlambatan hingga sampai tidak dibayarkan. Pokok kajian dalam penelitian ini adalah bagaimana sistem pembayaran upah tenaga kerja di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi menurut Undang-Undang Nomor 13 Tahun 2003 tentang Ketenagakerjaan dan bagaimana Tinjauan Hukum Ekonomi Syariah terhadap pengupahan di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi. Tujuan penelitian ini adalah untuk mengetahui bagaimana pembayaran upah di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi, dan untuk mengetahui bagaimana Tinjauan Hukum Ekonomi Syariah terhadap pembayaran upah tenaga kerja di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi. Metode penelitian yang digunakan dalam penelitian ini adalah jenis penelitian lapangan (field research) yaitu penelitian yang sumber datanya diambil secara langsung di lapangan dengan cara mengamati secara langsung kejadian yang terjadi di lokasi penelitian (observasi), wawancara langsung dengan responden, dan dokumentasi. Analisis data dalam penelitian ini adalah dengan metode Deskriptif Kualitatif dan disimpulkan secara dedukatif. Kesimpulan dari kajian ini adalah pembayaran upah tenaga kerja di PT. Tandan Abadi Mandiri belum sesuai dengan Pasal 1 ayat 30 Undang-Undang Nomor 13 Tahun 2003 Tentang Ketenagakerjaan karena pembayaran upahnya sering terlambat hingga sampai tidak dibayarkan, sehingga berpengaruh terhadap kesejahteraan pekerja. Sedangkan menurut pandangan Hukum Ekonomi Syariah pembayaran upah pekerja di PT. Tandan Abadi Mandiri Kabupaten Sarolangun Jambi telah sesuai dengan hukum Islam, karena dilihat dari bentuk, objek, dan akadnya yang tidak menyalahi aturan dalam hukum Islam, namun pada syarat ijarah adanya kerelaan tanpa keterpaksaan belum terpenuhi.

Kata Kunci: Perlindungan Hukum, Pengupahan, Ketenagakerjaan.
Tinjauan Hukum Ekonomi Syariah Terhadap Praktik Discount Dalam Member Card Pada Kasus Toko Rabbani Plaju Palembang
Authors: Nis Chairun , Armasito Armasito 
Published: March 2023

Manusia sebagai mahluk sosial tidak bisa lepas dari kehidupan perekonomian yaitu jual beli. Aktivitas jual beli dengan berbagai macam bentuk untuk membangun usaha yang memberikan keuntungan. Salah satunya praktik jual beli menggunakan member card yang bertujuan untuk mendapatkan discount. Praktik discount dalam member card yang terjadi di Toko Rabbani Plaju Palembang dalam penggunaan member cardnya untuk pendaftaran dikenakan biaya sebesar Rp.50.000 perlu diketahui bahwa dalam penggunaan member card tersebut hanya berlaku jangka waktu 1 tahun setelah itu adanya biaya perpanjangan member card tersebut sebesar Rp.25.000. Sistem praktik discount dalam member card yang terjadi di Toko Rabbani Plaju Palembang itu dinilai bertentangan dengan nilai syari’ah, asumsi atas hal tersebut disampaikan oleh Dr. Oni Sahroni yang merupakan Dewan Syariah Nasional Majelis Ulama Indonesia bahwa kartu discount dengan iuran berkala dan biaya keanggotaan itu tidak diperbolehkan dalam Islam karna ada unsur gharar. Adapun rumusan masalah dalam skripsi ini yaitu :1) Bagaimana praktik discount dalam member card di Toko Rabbani Plaju Palembang? 2) Bagaimana tinjauan hukum ekonomi syariah terhadap praktik discountdalam member card di Toko Rabbani Plaju Palembang?. Metode penelitian ini adalah field research dan metode jenis data yang digunakan yaitu kualitatif. Populasi dalam penelitian ini yaitu pengguna member card di Toko Rabbani Plaju Palembang dan sample yang digunakan berjumlah 8 orang. Teknik pengumpulan data dilakukan dengan studi lapangan dan studi kepustakaan. Data yang terkumpul kemudian dianalisis secara deskriptif kualitatif. Hasil penelitian ini adalah bahwa praktik discount dalam member card di Toko Rabbani Plaju apabila sudah mendaftar maka akan mendapatkan discount 10 % sampai15%,discount berlaku untuk semua barang tanpa adanya minimal pembelian dalam seminggu,Toko Rabbani Plaju Palembang ini juga pada saat akhir tahun selalu ada program promo discount 50 % tetapi hanya untuk yang ada member card saja. Menurut hukum ekonomi syariah bahwa discount dalam member card itu diperbolehkan. Dalam transaksi jual beli yang ditinjau dari hukum ekonomi syariah member card Rabbani ini jika sudah melakukan pendaftaran dengan berbayar atau gratis tentunya calon member sudah mengetahui akan mendapatkan discount didalam member card dengan cara harus memenuhi semua persyaratannya. Tentunya kedua belah pihak sudah saling tahu serta ridho apapun yang menjadi persyaratan dalam transaksi tersebut. Akan hal itu keduabelah pihak sama-sama mendapatkan keuntungan dan didalamnya tidak ada unsur penipuan karena biaya pembayaran pendaftaran atau perpanjangan member card tersebut termasuk ke dalam upah kerja.

Kata Kunci : Discount, Member Card, Jual beli