bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical utility of an immunoglobulin A‐based serological panel for the diagnosis of chronic enteropathy in dogs
Authors: Langlois Daniel K. , Pritchard Jessica C. , Tolbert M. Katherine , Jergens Albert E. , Block Gary , Hanzlicek Andrew S. , Jaffey Jared A. , Steiner Jörg M. , Marsilio Sina , Jablonski Sara A. 
Published: January 2023

AbstractBackgroundA panel of IgA‐based serologic assays might aid in the diagnosis of chronic enteropathy (CE) in dogs, a syndrome encompassing conditions such as food‐responsive enteropathy, immunosuppressant‐responsive enteropathy, and inflammatory bowel disease (also referred to as chronic inflammatory enteropathy). However, it is unclear whether these biomarkers discriminate between CE and other types of primary intestinal disorders.ObjectivesTo evaluate a diagnostic panel that measures serum concentrations of IgA directed against OmpC (ACA), canine calprotectin (ACNA), and gliadin‐derived peptides (AGA) in dogs with well‐characterized intestinal diseases.AnimalsFifty‐five dogs with primary intestinal disease.MethodsSerum ACA, ACNA, and AGA concentrations were measured in 30 dogs with CE and 25 dogs with other intestinal diseases (non‐CE population), including histoplasmosis, parasitism, E. coli‐associated granulomatous colitis, and lymphoma. Serum IgA concentrations were compared among populations, and sensitivities and specificities were calculated using laboratory‐provided cut‐points.ResultsTwenty‐six of 30 (87%) CE dogs and 21 of 25 (84%) non‐CE dogs had abnormal concentrations (intermediate or high) of at least 2 markers; these proportions were not significantly different (P = .99). A serum ACA concentration ≥15 EU/mL was 86.7% (95% confidence interval [CI], 69.3%‐96.2%) sensitive and 24.0% (95% CI, 9.4%‐45.1%) specific for CE diagnosis. High AGA concentrations were observed in 16 of 25 (64%) non‐CE dogs.Conclusions and Clinical ImportanceThe evaluated serologic markers were poorly specific for CE diagnosis, which raises concerns that their use in clinical practice might lead to misdiagnoses and delayed or even detrimental treatments in dogs with non‐CE intestinal diseases.
Children onychomycosis, a neglected dermatophytosis: A retrospective study of epidemiology and treatment
Authors: Song Ge , Zhang Meijie , Liu Weida , Liang Guanzhao 
Published: January 2023

AbstractBackgroundOnychomycosis was an ignored disease in children, and the prevalence was still unknown worldwide.ObjectivesThis study was conducted to investigate the prevalence and treatment regimens of onychomycosis in children younger than 18 years old.MethodsWe systemically reviewed all publications by searching the key terms to reveal the onychomycosis in children from 1990 to 2022.ResultsA total of 44 articles including 2,382 children with onychomycosis were enrolled in this study. The male to female ratio was 1.29:1. The youngest child was 35 days old and the average age was 9.8 years old. The duration of disease usually ranged from 7 days to 4 years. Onychomycosis in children was more prevalent in toenails compared to fingernails (77.6% vs. 18.4%), and 4% patients had both. A total of 527 children (22.12%) had concomitant tinea pedis infection, and in 267 patients (11.21%), their family members had onychomycosis or tinea pedis. The most common clinical type of onychomycosis was DLSO (67.74%) and the predominant isolates were T. rubrum (66.13%), followed by C. albicans (9.08%) and T. mentagrophytes complex (5.34%). There were 419 children (74.03%) receiving systematic treatment only, 74 patients (13.07%) receiving topical treatment only, and 73 patients (12.90%) receiving both systematic and topical treatment. Twelve patients (2.12%) had mild drug‐related side effects. During the follow‐up, 71.25% children were cured, 17.50% symptoms improved and 4.17% failed.ConclusionsOnychomycosis was underestimated in children and the diagnosis of onychomycosis should be properly considered in children with nail disorders. For mild patients, topical treatment can be a good choice, and oral antifungal drugs could be added to severe individuals under monitoring.
Experiences of families of prolonged critical illness survivors that are discharged home: An integrative review of the literature
Authors: Best Amy , Harvey Clare , Minton Claire 
Published: January 2023

AbstractBackgroundWithin the context of the increasing prevalence of prolonged critical illness, a situation intensified by the COVID‐19 global pandemic, advancing understanding of the experiences of families of survivors that are discharged home is important in understanding the complexity of life for these people.AimsTo examine research related to the experiences of families of survivors of prolonged critical illness that are discharged home.Study designThis review was conducted using the Whittemore and Knafl framework for integrated literature reviews. A literature search was conducted using the electronic databases of Web of Science, CINHAL, Scopus, and PubMed for English language studies published between January 2002 and October 2021. Article titles and abstracts were screened in view of finding a selection of articles that focussed on the experiences of families of people who have survived a prolonged intensive care stay that are discharged home. Study quality was assessed using the CASP (Critical Appraisal Skills Programme) tool. Data analysis of nine peer‐reviewed articles was informed by the Braun and Clarke approach to thematic analysis. The PRISMA guidelines were used to report the review process.ResultsNine articles were included in the review. Three major themes were identified, namely, (i) the negative impact on family caregiver health and well‐being, (ii) caregiver burden, and (iii) unmet support needs.ConclusionsFamilies of prolonged critical illness survivors that are discharged home face complex challenges that make their experience difficult and demanding. Family support needs once patients are discharged home are largely unrecognized in this population.Relevance to clinical practiceThis review evidences the need to investigate further the experiences of families of survivors of prolonged critical illness. Further qualitative research has the potential to help inform service provision and support for these people.
HSP90s are required for hypocotyl elongation during skotomorphogenesis and thermomorphogenesis via the COP1–ELF3–PIF4 pathway in Arabidopsis
Authors: Zeng Yue , Wang Jiayu , Huang Sha , Xie Yu , Zhu Tongdan , Liu Leyi , Li Lin 
Published: January 2023

Summary
Light and temperature are two key environmental signals that share several molecular components that, in turn, regulate plant growth. Darkness and high ambient temperatures promote skoto‐ and thermomorphogenesis, including stem elongation. Heat shock proteins 90 (HSP90s) facilitate the adaptation of organisms to various adverse environmental stimuli.
Here, we showed that HSP90s are required for hypocotyl elongation during both skoto‐ and thermomorphogenesis.
When HSP90s activities are impaired by the knockdown of HSP90s expression or the application of HSP90 inhibitors, the expression levels and protein abundance of PHYTOCHROME‐INTERACTING FACTOR 4 (PIF4) markedly decreased. EARLY FLOWERING 3 (ELF3) deficiency was resistant to the inhibition of HSP90s activities. Furthermore, HSP90s interacted with and destabilized ELF3. In the CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) mutant, the changes in endogenous PIF4 and ELF3 protein levels caused by the inhibition of HSP90s activities were abolished. HSP90s enhanced the interaction between COP1 and ELF3, reduced ELF3 functional effects on PIF4 and modulated hypocotyl elongation during skoto‐ and thermomorphogenesis.
Our results indicated that HSP90s participate in light and temperature signalling via the COP1–ELF3–PIF4 module to regulate hypocotyl growth in changing environments.
Personnel selection: A review of ways to maximize validity, diversity, and the applicant experience
Authors: Van Iddekinge Chad H. , Lievens Filip , Sackett Paul R. 
Published: January 2023

AbstractPersonnel Psychology has a long tradition of publishing important research on personnel selection. In this article, we review some of the key questions and findings from studies published in the journal and in the selection literature more broadly. In doing so, we focus on the various decisions organizations face regarding selection procedure development (e.g., use multiple selection procedures, contextualize procedure content), administration (e.g., provide pre‐test explanations, reveal target knowledge, skills, abilities, and other characteristics [KSAOs]), and scoring (e.g., weight predictors and criteria, use artificial intelligence). Further, we focus on how these decisions affect the validity of inferences drawn from the procedures, how use of the procedures may affect organizational diversity, and how applicants experience the procedures. We also consider factors such as cost and time. Based on our review, we highlight practical implications and key directions for future research.
Increased pupil and heart‐rate responses to sexual stimuli in men after physical exertion
Authors: Finke Johannes B. , Hahn Sebastian , Schächinger Hartmut , Klucken Tim 
Published: January 2023

AbstractPhysical stress has been found to enhance arousability by visual sexual stimuli on a short‐term basis, as reflected in higher phasic pupil dilation responses, probably mediated by sympathetic nervous system (SNS)‐related processes. However, previous research has not addressed the specificity of this effect in terms of emotional valence, that is, whether it reflects an instance of general excitation transfer or a more specific mechanism. Thus, to further investigate changes in sexual processing after acute stress exposure, 40 male participants underwent either a predominantly sympathetic stressor (3 min sustained handgrip) or similar control procedure. After stress induction, pictures varying in valence as well as sexual versus non‐sexual arousal were presented (for 5000 ms each). Using principal component analysis, pupillary responses during picture viewing were dissociated into fast and slow components (early vs. late response phases). In addition, startle eyeblink responses were elicited by bursts of white noise (50 ms, 105 dB) in half of the trials and recorded at the orbicularis oculi via electromyography. Skin conductance and heart rate were co‐registered, as well. While affective startle modulation and skin conductance responses to emotional stimuli were unaffected by previous stress exposure, both evoked heart‐rate deceleration (but not acceleration) and pupil responses were specifically enhanced with sexually arousing stimuli in stressed participants, and this effect was mediated by blood pressure reactivity as an index of preceding SNS activation. Taken together, our findings provide strong evidence for enhancement of sexual processing by acute stress exposure in men and suggest differential involvement of parasympathetic versus sympathetic mechanisms.
Role of microbial phytases in improving fish health
Authors: Priya  , Virmani Ishita , Pragya  , Goswami Ravi Kumar , Singh Bijender , Sharma Jai Gopal , Giri Bhoopander 
Published: January 2023

AbstractFishmeal is the most preferred protein source in aquafeed industry due to its balanced amino acid and fatty acid profile, but its limited global supply and high price value, necessitates researchers to focus on sustainable alternative sources of protein and plant‐based feed, to meet the growing demand of fish feed. Phytate is a reservoir of phosphorus present in the plants; however, its chelating ability makes it anti‐nutritional. Phytate forms complexes with minerals, proteins, lipids and carbohydrates, confining their accessibility in fish feeds, hence, additional dietary nutrients are required in the fish feed to overcome nutritional deficiencies. The elimination of phytate‐phosphorus through animal faeces and its pass on to aquatic bodies leads to enrichment of nutrients, eutrophication and algal blooms. Microbial phytase segregates phosphorus, minerals, proteins and lower inositol phosphates from phytate. The supplementation of fish feed with microbial phytase enhances the digestibility of minerals, due to which less nutrients are excreted in the faeces; therefore, minimizing pollution in water bodies. Monogastric and agastric animals inherently exhibit the deficiency of phytase; hence, supplementation of dietary material with phytase has been an emerging choice to make dietary nutrients available for fish. Moreover, microbial phytases have a broad pH range and are thermostable, which makes them an excellent choice for commercial fish feed production. Additionally, microbial phytase improves fish growth as these enzymes enhance nutrients bioavailability and their digestion. This review article presents the application of microbial phytases as a feed additive, and their role in enhancing fish growth.
Influence of parental knowledge and attitudes on the oral and dental health status of autistic children: A systematic review
Authors: Salmeh Abdulrahman , Al‐Saadi Meena , AlZaidi Nadia , Al Hamwi Noura , Jumaah Sarah Safaa , Karimzadeh Shamma , Dhafer Taiba , Al‐Rubaiay Ward , Al‐Rawi Natheer 
Published: January 2023

AbstractAimsThis paper aims to systematically review the current evidence surrounding the influence of parental knowledge and attitudes on the oral and dental health status of autistic children.Methods and ResultsData were sourced from EBSCOhost, ProQuest One Academic, Ovid MEDLINE, and Scopus. Additional records were manually identified through other sources. Literature search identified 610 relevant articles for screening, of which nine were ultimately selected for inclusion following full‐text review. A custom data collection sheet was constructed by the authors to extract data based on selected parameters addressing the focused research question. Extracted data were combined in an evidence table based on the collection sheet parameters. Study characteristics and findings were then descriptively summarized and compared. Due to heterogenicity, meta‐analysis was not viable. While all included cross‐sectional studies have predominantly shown no statistically significant association between parental knowledge and oral health, three experimental studies have conversely reported significant oral health improvements following educational interventions; suggesting a strong correlation.ConclusionAutistic children are susceptible to oral diseases, necessitating parental attention. Current evidence regarding this topic is limited and conflicting. The present systematic review faces limitations: included studies were few and predominantly cross‐sectional. Moreover, study samples were small, predominantly male, conveniently recruited, and geographically limited. This paper serves as a foundation to guide future research and inspire oral health education and wellness promotion programs.
Stratigraphic change in flow transformation processes recorded in early post‐rift deep‐marine intraslope lobe complexes
Authors: Martinez‐Doñate Ander , Kane Ian A. , Hodgson David M. , Privat Aurelia M.‐L. J. , Jackson Christopher A.‐L. , Schwarz Ernesto , Flint Stephen S. 
Published: January 2023

AbstractThe Early Jurassic Los Molles Formation in the Neuquén Basin of western Argentina is a rare example of well‐exposed syn‐rift to post‐rift stratigraphy. In the Chachil Graben, the onset of the early post‐rift stage is marked by drowning of a carbonate system and the development of two deep‐marine intraslope lobe complexes. This field‐based study in the Chachil Graben involved field mapping and correlating eleven stratigraphic logs, and petrographic analysis to document how grain size and texture within intraslope lobe sandstones change from the lobe centre to their frontal pinch‐out. Eight different bed‐scale facies are identified and inferred to be formed by turbulent (turbidites; Type A and B beds), transient turbulent–laminar (transitional flow deposits; Type C, D, E and F beds), laminar gravity flows (debrites; Type G) and post‐depositional clastic injections (injectites; Type H beds). Fifteen lobes form two stacked lobe complexes that show stratigraphic evolution from a lower argillaceous sandstone‐dominated lobe complex, built by transitional flow deposits, to an upper coarser‐grained, sandier lobe complex largely constructed by turbidites. Petrographic analysis quantified sandstone mineralogy, matrix content, grain size and sorting, revealing that both lobe complexes are volcanic arc‐sourced. This study proposes that the differences in the character of the two lobe complexes are due to maturation of sediment transport routes through progressive healing of the intraslope relief, with a concomitant decrease in substrate erosion and flow bulking. Also proposed here is a model for intraslope lobe complex development that accounts for the impact of flow‐confinement on flow behaviour and transformation induced by the inherited topography. Bed type distribution suggests that high‐density flows terminate more abruptly against confining slopes and produce greater depositional variability than lower‐density flows. This integrated petrographic, architectural and sedimentary process model provides new insights into how post‐rift intraslope lobe systems may act as hydrocarbon reservoirs, aquifers and carbon storage sites.
A dual‐process framework for diversity training to reduce discrimination in organizational settings
Authors: Gill Laura J. , Olson Michael A. 
Published: January 2023

AbstractDisputes about the value of Diversity Training (DT) stem partly from disputes about what DT should entail and what its expected outcomes should be. We answer previous reviews’ calls for approaches to DT that are grounded in empirically supported theoretical frameworks. Specifically, and based on longstanding theory and research on attitude–behavior relations, we offer a dual‐process framework that identifies key factors for interventions to reduce individual‐level discrimination in organizational settings, including (a) automatic attitudes/bias, (b) awareness of the impact of bias, (c) motives relating to egalitarianism and conformity, and (d) the opportunity to engage in deliberative decision making. We offer suggestions, where available, for how DT might employ basic research known to impact these factors to construct more effective interventions. Finally, we offer guidance for targeted rather than “one‐size‐fits‐all” approaches to DT and advocate for an integration of DT tailored to individuals with structural interventions tailored to organizations.
Structural racism and health in the age of COVID‐19: A selective review with policy implications
Authors: Brondolo Elizabeth , Kaur Amandeep , Flores Melissa 
Published: January 2023

AbstractStructural racism encompasses the effects of racial bias across all systems of society. A growing body of data indicates that structural racism contributes to racial inequities in health across the lifespan. Investigators have documented associations of different dimensions of structural racism, including cultural and institutional discrimination, to health. To clarify and integrate the scope of these data, we examine a broad array of manifestations of both cultural and institutional racism and review their associations to specific health effects outcomes. We examine effects on COVID‐19 prevalence and mortality, but also investigate data on birth outcomes and premature mortality to gain insight into health effects at each end of the lifespan. Given the pervasive and well‐documented history of racism facing Black Americans, we focus this review on the effects of structural racism on the health of Black populations in the United States.To examine the association of cultural discrimination to health, we review studies of prejudicial communications assessed with measures of area‐level prejudice, leader communications of prejudice, and reactions to race‐related cultural events. To examine the association of institutional discrimination to health, we examine laws and institutional policies that discriminated against Black Americans and shaped social and physical environments characterized by residential racial segregation and disadvantage, occupational segregation, and restricted voting rights, among other manifestations of inequity. As we document, research has demonstrated associations of cultural racism to birth outcomes and mortality, data are lacking on direct relations to COVID‐19 mortality. Institutional discrimination has been consistently linked to the increased prevalence of and mortality from COVID‐19, and some aspects are associated with birth outcomes and mortality. Understanding the interrelations among cultural and institutional aspects of discrimination and their historical roots have important implications for the development of policies and interventions to reduce structural racism and mitigate its effects on health.
Cognitive behavioral therapy (CBT) plus attention bias modification (ABM) reduces anxiety sensitivity and depressive symptoms in panic disorder: A pilot randomized trial
Authors: Zainal Nur Hani , Hellberg Samantha N. , Kabel Katherine E. , Hotchkin Claire M. , Baker Amanda W. 
Published: January 2023

BackgroundCognitive bias theories propose that reducing threat hypervigilance in mental disorders can augment cognitive behavioral therapy (CBT) outcomes. However, no studies have tested whether adding attention bias modification (ABM) can effectively enhance CBT's effects on anxiety sensitivity (AS), electromyography (EMG), and skin conductance (SC) for panic disorder (PD). This pilot randomized controlled trial (RCT) thus aimed to evaluate the efficacy of CBT + ABM (vs. CBT plus attention training placebo; PBO) on those outcomes.MethodThis study is a secondary analysis (Baker et al., 2020). Adults with PD were randomized to receive CBT + ABM (n = 11) or CBT + PBO (n = 12). Before each of the first five CBT sessions, CBT + ABM and CBT + PBO participants completed a 15‐min ABM task or attention training PBO, respectively. AS and depression severity as well as SC and EMG during habituation to a loud‐tone startle paradigm were assessed. Hierarchical Bayesian analyses were conducted.ResultsDuring pre‐post‐treatment and pre‐follow‐up, CBM + ABM (vs. CBT + PBO) led to a notably greater reduction in ASI–Physical (between‐group d = −1.26 to −1.25), ASI‐Cognitive (d = −1.16 to −1.10), and depression severity (d = −1.23 to −0.99). However, no between‐group difference was observed for ASI‐Social, EMG, or SC indices.DiscussionAdding a brief computerized ABM intervention to CBT for PD protocols may enhance therapeutic change.
Suffering for Justice in Anne Conway and Maria W. Stewart
Authors: Yenter Timothy 
Published: January 2023

AbstractAnne Conway and Maria W. Stewart are quietly revolutionary philosophers who provide valuable insights into the nature of suffering and its relation to justice. Conway scholars have claimed that she offers a theodicy, trying to reconcile suffering with the existence of a just God. However, this does not make sense of her arguments or audience. Instead, we should see her as a theoretician of the role of suffering in a person's life. Moving beyond the personal, Stewart's emphasis on social sources of suffering leads her to posit a vision for bringing about a more just society in the near term that is absent in Conway. Both philosophers provide fascinating insight into how to theorize suffering and justice, including the role of unity in a just society.