bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heterotypic interactions in the dilute phase can drive co-condensation of prion-like low-complexity domains of FET proteins and mammalian SWI/SNF complex
Authors: Davis Richoo B. , Supakar Anushka , Ranganath Aishwarya Kanchi , Moosa Mahdi Muhammad , Banerjee Priya R. 
Published: April 2023

AbstractPrion-like domains (PLDs) are low-complexity protein sequences enriched within nucleic acid-binding proteins including those involved in transcription and RNA processing. PLDs of FUS and EWSR1 play key roles in recruiting chromatin remodeler mammalian SWI/SNF complex to oncogenic FET fusion protein condensates. Here, we show that disordered low-complexity domains of multiple SWI/SNF subunits are prion-like with a strong propensity to undergo intracellular phase separation. These PLDs engage in sequence-specific heterotypic interactions with the PLD of FUS in the dilute phase at sub-saturation conditions, leading to the formation of PLD co-condensates. In the dense phase, homotypic and heterotypic PLD interactions are highly cooperative, resulting in the co-mixing of individual PLD phases and forming spatially homogeneous co-condensates. Heterotypic PLD-mediated positive cooperativity in protein-protein interaction networks is likely to play key roles in the co-phase separation of mSWI/SNF complex with transcription factors containing homologous low-complexity domains.
CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats
Authors: Huckleberry Kylie A , Calitri Roberto , Li Anna J. , Mejdell Mackenna , Singh Ashna , Bhutani Vasvi , Laine Mikaela A , Nastase Andrei S. , Morena Maria , Hill Matthew N , Shansky Rebecca M 
Published: April 2023

AbstractIncreasing evidence suggests that the neurobiological processes that govern learning and memory can be different in males and females, and here we asked specifically whether the endocannabinoid (eCB) system could modulate Pavlovian fear conditioning in a sex-dependent manner. Systemic (i.p.) injection of CB1R antagonist AM251 in adult male and female Sprague Dawley rats prior to auditory cued fear conditioning produced a female-specific increase in freezing that persisted across extinction and extinction retrieval tests but was prevented by co-administration of TRPV1R antagonist Capsazepine. Notably, AM251 also produced robust freezing in a novel context prior to auditory cue presentation the day following drug administration, but not the day of, suggesting that CB1R blockade elicited contextual fear generalization in females. To identify a potential synaptic mechanism for these sex differences, we next used liquid chromatography/tandem mass spectrometry, Western Blot, and confocal-assisted immunofluorescence techniques to quantify anandamide (AEA), TRPV1R, and perisomatic CB1R expression, respectively, focusing on the ventral hippocampus (vHip). Fear conditioning elicited increased vHip AEA levels in females only, and in both sexes, CB1R expression around vHip efferents targeting the basolateral amygdala (BLA) was twice that at neighboring vHip neurons. Finally, quantification of the vHip-BLA projections themselves revealed that females have over twice the number of neurons in this pathway that males do. Together, our data support a model in which sexual dimorphism in vHip-BLA circuitry promotes a female-specific dependence on CB1Rs for context processing that is sensitive to TRPV1-mediated disruption when CB1Rs are blocked.
Dissociable roles of the auditory midbrain and cortex in processing the statistical features of natural sound textures
Authors: Peng Fei , Harper Nicol S. , Mishra Ambika Prasad , Auksztulewicz Ryszard , Schnupp Jan W.H. 
Published: April 2023

AbstractIt is well established that sound texture perception takes advantage of a hierarchy of time-averaged statistical features of acoustic stimuli, but much remains unclear about how these statistical features are processed in auditory subcortical and cortical regions. Here, we compared the neural representation of sound textures in the inferior colliculus (IC), and primary and non-primary auditory cortex (AC) of anesthetized rats with texture morph stimuli which gradually add statistical features of increasingly higher order. We generated texture morphs for a representative subset of 13 sound textures, chosen to span the three principal component dimensions of a corpus of 200 natural texture recordings. For each of the 13 texture types, six different exemplar morphs were synthesized using different random seeds. All exemplars of each texture type have the same long term statistics, but they differ in their acoustic waveforms. Meanwhile, different texture types differ in statistical features as well as waveforms. An analysis of transient and ongoing multi-unit responses to our stimulus set showed that the IC units were sensitive to every type of statistical feature, albeit to a varying extent, but only a small proportion of AC units were overtly sensitive to any statistical features. Differences in texture types explained more of the variance of IC neural responses than did differences in exemplars, indicating a degree of “texture-type tuning” in the IC, but this was, perhaps surprisingly, not the case for AC responses. We also evaluated the accuracy of texture type classification from single-trial population activity and found that IC responses became more informative as more summary statistics were included in the texture morphs, while for AC population responses classification performance remained constant, and consistently lower, than for the IC. These results argue against the idea that AC plays an important role in encoding statistical features of natural sound textures.
Dual use insurance for annual forage producers: comparing risk management alternatives
Authors: Graff Natalie A. , Fischer Bart L. , Bryant Henry L. , Anderson David P. 
Published: April 2023

PurposeThe purpose of this paper is to evaluate the Dual Use (DU) Option – a crop insurance policy created by the 2018 Farm Bill – relative to other policies available to dual-purpose annual forage producers. The new policy combines existing rainfall-based policies for annual forage crops and multi-peril policies for grain, allowing coverage for multiple crop uses on the same acres during the same growing season.Design/methodology/approachThe paper uses a simulation model to examine crop insurance choices for a typical Texas dual-purpose wheat farm. The certainty equivalent (CE) of wealth is used to rank choices within and between three insurance plans and to analyze the effects of those choices over a range of producer risk aversion levels and for three cases of yield expectations.FindingsThe DU Option is more preferred as risk aversion increases, but it is not universally preferred. Therefore, while the policy can be a viable risk management tool, certain restrictions may be limiting its effectiveness.Practical implicationsThe findings of this paper can help explain farm-level decision making related to dual-purpose annual forage crop insurance program choices.Originality/valueThis paper contributes to the literature by documenting a new crop insurance program made available in the 2018 Farm Bill and provides insights into producers' possible choices by evaluating extensive scenarios.
Dual innovation of the business model: the regulatory role of entrepreneurial orientation in family firms
Authors: Ge Jingguang , Li Leiming 
Published: April 2023

Purpose
Family farms are seen as a powerful force for rural development, and they are gaining more and more research attention. This study aims to explore the relationship between the social networks of family farms and the dual innovation of the family farm business model from the perspective of entrepreneurial orientation.

Design/methodology/approach
Using a questionnaire survey of 169 family farms in Qingdao, China, descriptive and inferential statistics were used to analyze the data collected. The study hypothesis was tested using inferential tests (regression analysis).

Findings
The study results show that innovative, efficiency- and novelty-based business models facilitated by social networks have a favorable and significant impact on the performance of family farms. Furthermore, the relationship between social networks and new business model creation is positively influenced by an entrepreneurial orientation.

Originality/value
This study is distinctive in that it examines the mechanisms underlying family farm growth from an entrepreneurial standpoint, classifying family farm social networks for the first time into social, market and governmental categories and looking at their impact on the creation of new business models. In addition, it looks into the relationship between the innovation and social network aspect of the family farm business model from an entrepreneurial perspective, offering fresh insight into this connection. It also examines the family farm business model’s connection to innovation and social networks from an entrepreneurial standpoint, providing new insight into this relationship.
Critical factors for involvement in customers’ product development: an SME perspective
Authors: Flankegård Filip , Johansson Glenn , Granlund Anna 
Published: April 2023

PurposeThis paper aims to identify critical factors that influence small and medium-sized enterprise (SME) suppliers’ involvement in their customers’ product development and contrast these with the factors identified from the customer perspective.Design/methodology/approachA multiple case study approach was used, including four companies. Data were collected through 32 semi-structured interviews, six workshops and documents.FindingsA model is presented that merges this study’s nine identified critical factors with seven critical factors from the customer perspective. The model provides a dual perspective of supplier involvement in product development, wherein the supplier and customer perspectives are concurrently addressed. Some factors are unique for the supplier, but several mirror those on the customer side.Research limitations/implicationsThe study is based on data from SME suppliers in Northern Europe. As it is expected that SME companies are more constrained by limited resources, future studies could study critical factors at larger suppliers.Practical implicationsCustomers and suppliers having insights about the critical factors can provide better conditions for product development for the other actor; for example, when evaluating customer–supplier integration.Originality/valueThe presented model of critical factors provides a more nuanced picture of supplier involvement in product development as prior research has been biased toward the customer perspective. This study emphasizes the importance of contextual information that has been unnoticed in the literature.
Monitoring fluid saturation in reservoirs using time‐lapse full‐waveform inversion
Authors: Mardan Amir , Giroux Bernard , Fabien‐Ouellet Gabriel , Saberi Mohammad Reza 
Published: April 2023

AbstractMonitoring the rock physics properties of the subsurface is of great importance for reservoir management. For either oil and gas applications or CO2 storage, seismic data are a valuable source of information for tracking changes in elastic properties which can be related to fluids saturation and pressure changes within the reservoir. Changes in elastic properties can be estimated with time‐lapse full‐waveform inversion. Monitoring rock physics properties, such as saturation, with time‐lapse full‐waveform inversion is usually a two‐step process: first, elastic properties are estimated with full‐waveform inversion, then the rock physics properties are estimated with rock physics inversion. However, multiparameter time‐lapse full‐waveform inversion is prone to crosstalk between parameter classes across different vintages. This leads to leakage from one parameter class to another, which, in turn, can introduce large errors in the estimated rock physics parameters. To avoid inaccuracies caused by crosstalk and the two‐step inversion strategy, we reformulate time‐lapse full‐waveform inversion to estimate directly the changes in the rock physics properties. Using Gassmann's model, we adopt a new parameterization containing porosity, clay content and water saturation. In the context of reservoir monitoring, changes are assumed to be induced by fluid substitution only. The porosity and clay content can thus be kept constant during time‐lapse inversion. We compare this parameterization with the usual density–velocity parameterization for different benchmark models. Results indicate that the proposed parameterization eliminates crosstalk between parameters of different vintages, leading to a more accurate estimation of saturation changes. We also show that using the parameterization based on porosity, clay content and water saturation, the elastic changes can be monitored more accurately.
Rethinking Postwar Liberalism: The Road to 2010 and Beyond
Authors: Sloman Peter 
Published: April 2023

AbstractThe nineteenth and early twentieth century Liberal Party has been well served by British political historians. By contrast, research on the post‐1945 Liberal Party and Liberal Democrats has become a specialised field, with strong empirical foundations (including in biographies and political science work) but few connections with the larger narratives that historians tell about postwar Britain. This article explores how the story of the ‘long Liberal revival’ from the late 1950s to the 2010–15 coalition might be reintegrated with contemporary historiography, including debates about deindustrialisation, class dealignment and the rise of ‘popular individualism’. It argues that careful attention to the nature and limits of Liberals’ political agency can help us understand the changing meaning and significance of third‐party politics in Britain.
Mitigating the “Cobra Effect” when pursuing organizational resilience
Authors: Zighan Saad 
Published: April 2023

AbstractThis paper is a systematic literature review of organizational resilience. It aims to identify the reasons for the unintended consequences that may occur when organizations pursue resilience and how these unintended consequences could be mitigated. The analysis of 68 articles published between 2017 and 2022 indicates that organizations could have unintended consequences when pursuing organizational resilience, resulting from the organizational resilience conceptualization, models, practices, levels and the paradox of change. Consequently, several unintended consequences may arise when implementing a resilience strategy. This includes lessened leadership effectiveness, the pursuit of unrealistic objectives, low organizational creativity and innovation, overreliance on a single strategy, compromised values, fragile relationships, a short‐term focus and organizational culture. Therefore, the overall construct aspects of organizational resilience should be researched and analyzed further by gathering additional empirical data that sheds more light on these issues. Aside from the challenge of defining and measuring organizational resilience, there is variability in how organizational resilience is developed. It has also been operationalized in various ways, with limited insight into empirical methods to identify resilience against future hardships. Although the notion is promising, it has been criticized for being ambiguous and lacking a uniform explanation, diminishing its relevance for practice.
Racial Diversity Exposure and Firm Responses Following the Murder of George Floyd
Authors: BALAKRISHNAN KARTHIK , COPAT RAFAEL , DE LA PARRA DANIELA , RAMESH K. 
Published: April 2023

ABSTRACTGeorge Floyd's murder caused many firms to reveal how exposed they are to racial diversity issues. We examine investor and firm behaviors after this socially significant event to provide evidence on the valuation effects of the exposure and ensuing corporate responses. We develop a text‐based measure of a firm's exposure to racial diversity issues from conference call transcripts and find that, after the murder of George Floyd, firms with diversity exposure experience a stock price decrease of approximately 0.7% around the date of the conference call. We provide evidence that this effect is attributable to race‐related exposure and not gender‐related exposure. Initiatives taken by firms mitigate the negative market reaction. We document that firms with racial diversity exposure respond by appointing Black directors. The stock market views appointments of Black directors more favorably after George Floyd's murder, except when they are perceived as symbolic. We also find that firms with greater exposure to racial diversity are more likely to establish diversity, equity, and inclusion (DEI) departments, appoint DEI leaders, specify diversity goals, increase supply chain diversity, and donate to racial justice causes. Our paper provides evidence that exposure to racial diversity issues adversely affects firm value, and companies address the exposure by taking actions.
Celiac disease and risk of neuropsychiatric disorders: A nationwide cohort study
Authors: Hansen Susanne , Osler Merete , Thysen Sanne Marie , Rumessen Jüri J. , Linneberg Allan , Kårhus Line Lund 
Published: April 2023

AbstractIntroductionPrevious studies have indicated that patients with celiac disease (CD) may have an increased risk of developing neuropsychiatric disorders. However, large‐scale epidemiologic studies on the topic are still scarce. We aimed to examine the association between CD and development of neuropsychiatric disorders during an 18‐year follow‐up period.MethodsWe conducted a prospective cohort study. All Danish patients with an incident diagnosis of CD (ICD‐10 K90.0) from 2000 to 2018 were identified in nationwide registries and compared with birthdate‐ and sex‐matched controls (variable 1:10 ratio) for the development of a neuropsychiatric disease. Individual neuropsychiatric diseases were also examined. The absolute risk was calculated by the cumulative incidence, and the relative risk was estimated in Cox regression models.ResultsWe identified a cohort of 6329 patients with CD diagnosed from 2000 to 2018 and 63,287 matches at risk for developing incident neuropsychiatric disorders. The cumulative incidence of development of any neuropsychiatric disorder was 3.9%, 14.9%, 24.8%, 35.9% after 1, 5, 10, and 15 years of follow‐up, respectively, in patients with CD compared with 1.8%, 9.3%, 18.3%, and 27.0% in controls. Gray's test for equality p < 0.001. The relative risk was HR = 1.58 (95% confidence interval: 1.49–1.68) in CD patients compared with matches. For the individual outcomes, CD was associated with an increased relative risk of developing anxiety, depression, eating disorders, epilepsy, migraine, and stress. We also found indications of an increased relative risk of ADHD, alcoholism, bipolar disorders, and drug abuse, although the associations were less clear. No associations were found between CD and dementia, Parkinson's disease, and schizophrenia.ConclusionsIn this nationwide study including more than 6000 patients with CD, we found an increased risk of development of a neuropsychiatric disorder compared with age‐ and sex‐matched controls. The causes and the clinical relevance of these associations remain to be elucidated.
Climatic, geographic and anthropogenic factors shape the structure of bat–fruit networks in the Neotropical region
Authors: Ligo Ana Beatriz , Laurindo Rafael de Souza , Faria Lucas Del Bianco , Gregorin Renato 
Published: April 2023

AbstractNatural and anthropogenic environmental gradients are associated with changes in species richness, abundance and resource use. There is increasing interest in understanding how the structure of interaction networks varies along environmental gradients, but most studies have focused on bird–plant networks, while studies on mutualistic networks formed by other vertebrate groups are scarce. Here, we compiled a database of 48 bat–fruit networks distributed in the Neotropical region and evaluated the influence of annual precipitation, annual mean temperature, latitude, altitude and human impacts on nestedness, modularity, specialization, interaction diversity and species richness. Furthermore, we characterized the distribution of the roles of bat species in networks of interactions inserted in different biomes of the Neotropical region. We found that annual mean temperature increased nestedness, but decreased modularity and diversity of interactions. In addition, the diversity of interactions was greater in areas with higher annual precipitation, with less human impact and in lower latitude regions. Plant richness increased in regions with higher annual precipitation, while latitude negatively affected both plant and bat richness. Regarding the role played by bat species, we observed that most species occupy peripheral positions and only 4% of the species acted as connectors. Consistent with previous studies that evaluated other mutualistic systems, we demonstrated that the structure of bat–fruit networks is influenced by climatic, geographic and anthropogenic factors. These findings enhance our understanding of how ecological communities are structured along an environmental gradient and allow us to understand how these systems can be affected by changes in climate and land use.
Revision of Nothepyris Evans, 1973 (Hymenoptera: Bethylidae), with description of four new species
Authors: Colombo Wesley D. , Azevedo Celso O. 
Published: April 2023

AbstractNothepyris Evans, 1973 is revised. Six species are recognised, two being previously described species, Nothepyris brasiliensis Evans, 1973 and Nothepyris pretiosus Colombo & Azevedo, 2019, and four species described and illustrated as new, Nothepyris beedrill sp. nov., Nothepyris combee sp. nov., Nothepyris durant sp. nov. and Nothepyris vespiquen sp. nov. The species Nothepyris sulcatus (Azevedo, 1999) syn. nov. is proposed as a junior synonym of Nothepyris brasiliensis. For the first time, males of this genus are described, and the morphology of the male genitalia is compared and discussed with other Scleroderminae. An updated taxonomic key to all species for both sexes is presented.
Exploring the range expansion of the yellow‐spotted longhorn beetle Psacothea hilaris hilaris in northern Italy
Authors: Lupi Daniela , Malabusini Serena , de Milato Silvia , Heinzl Alessandro Luigi , Ruzzier Enrico , Bani Luciano , Savoldelli Sara , Jucker Costanza 
Published: April 2023

Abstract
Psacothea hilaris hilaris is an exotic cerambycid detected in Lombardy (northern Italy) in 2005 and now established and undergoing an expansion phase. The species constitutes a serious pest for Ficus spp. and Morus spp.
The aim of this work is to update the distribution area of the species in Italy, investigating its expansion over 16 years. Data were acquired through the authors' direct field records and community science, by data mining on national and international web platforms and social networks. Reports were analysed and GPS points plotted in ArcMap 10.8.1 to obtain distribution maps.
Of the records collected, 34% were acquired during field surveys, 22% via e‐mail and 44% through on‐line forums and social networks.
Adults of P. h. hilaris showed a long period of activity, from April to the beginning of December, with a peak of presence from June to September. The presence of the pest has been ascertained over six provinces in Lombardy covering an area estimated at more than 1750 km2 in 2021. New detections occurred within 2 km of a known infestation from the previous year in 41.6% of cases, and between 2 and 4 km away in 37.7% of cases. The mean rate of range expansion estimated from reported records was 3.17 ± 0.33 km/year from 2010 to 2021. After an initial phase of settlement, the insect is now spreading southward.
Given the relevant phytosanitary interest that the species may have for fig plants in Italy and in the Mediterranean Basin, it is fundamental to deepen the knowledge about its flight biology, dynamics and active dispersal capabilities in order to estimate the future range expansion.