bluuebunny/crossref_metadata_2025_split huggingface dataset:
The influence of inter-annual temperature variability on the Greenland Ice Sheet volume
Authors: Lauritzen Mikkel , Aðalgeirsdóttir Guðfinna , Rathmann Nicholas , Grinsted Aslak , Noël Brice , Hvidberg Christine S. 
Published: August 2023

AbstractThe Greenland Ice Sheet has become an increasingly larger contributor to sea level rise in the past two decades and is projected to continue to lose mass. Climate variability is expected to increase under future warming, but the effect of climate variability on the Greenland Ice Sheet volume is poorly understood and is adding to the uncertainty of the projected mass loss. Here we quantify the influence of inter-annual temperature variability on mass loss from the Greenland Ice Sheet using the PISM model. We construct an ensemble of temperature-forcing fields that accounts for inter-annual variability in temperature using reanalysis data from NOAA-CIRES over the period 1851–2014. We investigate the steady-state and transient response of the Greenland Ice Sheet. We find that the simulated steady-state ice-sheet volume decreases by 1.9 ± 0.4 cm of sea level equivalent when forced with a varying temperature forcing compared to a constant temperature forcing, and by 11.5 ± 1.4 cm when the variability is doubled. The northern basins are particularly sensitive with a change in volume of 0.9–1.1%. Our results emphasize the importance of including temperature variability in projections of future mass loss.
Determination of Sentences in India: Policy and Practice
Authors: Singh Parth 
Published: August 2023

AbstractJudiciary and litigation are the two most prominent types of activities within the legal profession. The judicial aspect of the profession entails the interpretation of laws and the administration of justice in a fair and impartial manner. As a concept, justice entails protecting society from offenders and evildoers who deviate from society’s norms and engage in illegal behaviour by punishing and sentencing them. Due to the predominance of the human factor in the legal profession, which has such a significant impact on the lives of all members of society, it is crucial to investigate whether there is a guiding force behind dispensing justice and, if so, how effective these guidelines or policy measures have been. As crime rates rise and societal standards fall in the contemporary era, the legal profession grapples with the complexities of modern criminal behaviour. Particularly in the realm of judicial sentencing, there is a need for guidelines that account for the diversity of crimes and their individualistic nature. In India, long pungencies in court cases and a decline in the State’s conviction rate further exacerbate these issues. This paper examines the pressing need for comprehensive, well-structured sentencing guidelines that promote transparency, fairness and efficiency in the judicial process. Through a detailed review of recent high-profile court cases and an analysis of current practices and policies, this paper highlights the urgency of reform in the sentencing process to enhance public trust in the legal system. This article provides additional information on the subject.
Evolved galaxies in high-density environments across 2.0 ≤ z < 4.2 using the ZFOURGE survey
Authors: Hartzenberg Georgia R. , Cowley Michael J. , Hopkins Andrew M. , Allen Rebecca J. 
Published: August 2023

Abstract
To explore the role environment plays in influencing galaxy evolution at high redshifts, we study

$2.0\leq z<4.2$

environments using the FourStar Galaxy Evolution (ZFOURGE) survey. Using galaxies from the COSMOS legacy field with

${\rm log(M_{*}/M_{\odot})}\geq9.5$

, we use a seventh nearest neighbour density estimator to quantify galaxy environment, dividing this into bins of low-, intermediate-, and high-density. We discover new high-density environment candidates across

$2.0\leq z<2.4$

and

$3.1\leq z<4.2$

. We analyse the quiescent fraction, stellar mass and specific star formation rate (sSFR) of our galaxies to understand how these vary with redshift and environment. Our results reveal that, across

$2.0\leq z<2.4$

, the high-density environments are the most significant regions, which consist of elevated quiescent fractions,

${\rm log(M_{*}/M_{\odot})}\geq10.2$

massive galaxies and suppressed star formation activity. At

$3.1\leq z<4.2$

, we find that high-density regions consist of elevated stellar masses but require more complete samples of quiescent and sSFR data to study the effects of environment in more detail at these higher redshifts. Overall, our results suggest that well-evolved, passive galaxies are already in place in high-density environments at

$z\sim2.4$

, and that the Butcher–Oemler effect and SFR-density relation may not reverse towards higher redshifts as previously thought.
Does the primate face cue personality?
Authors: Wilson Vanessa A D , Masilkova Michaela 
Published: August 2023

AbstractWhen looking at others, primates primarily focus on the face – detecting the face first and looking at it longer than other parts of the body. This is because primate faces, even without expression, convey trait information crucial for navigating social relationships. Recent studies on primates, including humans, have linked facial features, specifically facial width-to-height ratio (fWHR), to rank and Dominance-related personality traits, suggesting these links’ potential role in social decisions. However, studies on the association between dominance and fWHR report contradictory results in humans and variable patterns in nonhuman primates. It is also not clear whether and how nonhuman primates perceive different facial cues to personality traits and whether these may have evolved as social signals. This review summarises the variable facial-personality links, their underlying proximate and evolutionary mechanisms and their perception across primates. We emphasise the importance of employing comparative research, including various primate species and human populations, to disentangle phylogeny from socio-ecological drivers and to understand the selection pressures driving the facial-personality links in humans. Finally, we encourage researchers to move away from single facial measures and towards holistic measures and to complement perception studies using neuroscientific methods.
The Western Design Revised: Death, Dissent, and Discontent on the Gloucester, 1654–1656
Authors: Redding Benjamin W. D. 
Published: August 2023

AbstractIn December 1654 a large naval force departed from Portsmouth and sailed across the Atlantic. Its goal was to expand the English Commonwealth in the Caribbean at the expense of Spanish colonies. The Gloucester, a third-rate frigate recently constructed as part of Oliver Cromwell's ambitious shipbuilding programme, was one of the largest and most heavily armed warships of the expedition. Combining analysis of courts martial accounts, inventories, journals, letters, sailing instructions, and wills, this article argues for the Gloucester's importance as a case study and microcosm for understanding the economic, political, religious, and social problems that the navy and wider Protectorate faced. It revises traditional historiography about the topic that has underestimated the significance of the naval context to the Western Design. Crucial to this new history is that the extreme hardships and religious divisions created tensions that targeted the leadership of Admiral William Goodsonn. Of particular importance in this narrative is Benjamin Blake, captain of the Gloucester, who clashed with Goodsonn over key policies. By focusing on the Gloucester and exploring its crew's experiences, this article shows that the English navy was a restricted and internally conflicted force when operating at the peripheries of the state network.
Leishmania (L.) amazonensis LaLRR17 increases parasite entry in macrophage by a mechanism dependent on GRP78
Authors: Peña Mauricio S. , Tang Fenny Hui Fen , Franco Fernando Alves de Lima , Rodrigues Alessandro Taunay , Carrara Guilherme Moreira Paiva , Araujo Thaís Larissa Silva , Giordano Ricardo José , Palmisano Giuseppe , de Camargo Maristela Martins , Uliana Silvia Reni Bortolin , Stolf Beatriz Simonsen 
Published: August 2023

AbstractLeishmaniases affect 12 million people worldwide. They are caused by Leishmania spp., protozoan parasites transmitted to mammals by female phlebotomine flies. During the life cycle, promastigote forms of the parasite live in the gut of infected sandflies and convert into amastigotes inside the vertebrate macrophages. The parasite evades macrophage's microbicidal responses due to virulence factors that affect parasite phagocytosis, survival and/or proliferation. The interaction between Leishmania and macrophage molecules is essential to phagocytosis and parasite survival. Proteins containing leucine-rich repeats (LRRs) are common in several organisms, and these motifs are usually involved in protein–protein interactions. We have identified the LRR17 gene, which encodes a protein with 6 LRR domains, in the genomes of several Leishmania species. We show here that promastigotes of Leishmania (L.) amazonensis overexpressing LaLRR17 are more infective in vitro. We produced recombinant LaLRR17 protein and identified macrophage 78 kDa glucose-regulated protein (GRP78) as a ligand for LaLRR17 employing affinity chromatography followed by mass spectrometry. We showed that GRP78 binds to LaLRR17 and that its blocking precludes the increase of infection conferred by LaLRR17. Our results are the first to report LRR17 gene and protein, and we hope they stimulate further studies on how this protein increases phagocytosis of Leishmania.
Associations between polygenic risk scores and accelerated brain ageing in smokers
Authors: Yang Zeyu , Zhao Wei , Linli Zeqiang , Guo Shuixia , Feng Jianfeng 
Published: August 2023

AbstractBackgroundSmoking contributes to a variety of neurodegenerative diseases and neurobiological abnormalities, suggesting that smoking is associated with accelerated brain aging. However, the neurobiological mechanisms affected by smoking, and whether they are genetically influenced, remain to be investigated.MethodsUsing structural magnetic resonance imaging data from the UK Biobank (n = 33 293), a brain age predictor was trained on non-smoking healthy groups and tested on smokers to obtain the BrainAge Gap (BAG). The cumulative effect of multiple common genetic variants associated with smoking was then calculated to acquire a polygenic risk score (PRS). The relationship between PRS, BAG, total gray matter volume (tGMV), and smoking parameters was explored and further genes included in the PRS were annotated to identify potential molecular mechanisms affected by smoking.ResultsThe BrainAge in smokers was predicted with very high accuracy (r = 0.725, MAE = 4.16). Smokers had a greater BAG (Cohen's d = 0.074, p < 0.0001) and higher PRS (Cohen's d = 0.63, p < 0.0001) than non-smokers. A higher PRS was associated with increased amount of smoking, mediated by BAG and tGMV. Several neurotransmitters and ion channel pathways were enriched in the group of smoking-related genes involved in addiction, brain synaptic plasticity, and some neurological disorders.ConclusionBy using a simplified single indicator of the entire brain (BAG) in combination with the PRS, this study highlights the greater BAG in smokers and its linkage with genes and smoking behavior, providing insight into the neurobiological underpinnings and potential features of smoking-related aging.
Predicting long-term outcome in anorexia nervosa: a machine learning analysis of brain structure at different stages of weight recovery
Authors: Arold Dominic , Bernardoni Fabio , Geisler Daniel , Doose Arne , Uen Volkan , Boehm Ilka , Roessner Veit , King Joseph A. , Ehrlich Stefan 
Published: August 2023

AbstractBackgroundAnorexia nervosa (AN) is characterized by sizable, widespread gray matter (GM) reductions in the acutely underweight state. However, evidence for persistent alterations after weight-restoration has been surprisingly scarce despite high relapse rates, frequent transitions to other psychiatric disorders, and generally unfavorable outcome. While most studies investigated brain regions separately (univariate analysis), psychiatric disorders can be conceptualized as brain network disorders characterized by multivariate alterations with only subtle local effects. We tested for persistent multivariate structural brain alterations in weight-restored individuals with a history of AN, investigated their putative biological substrate and relation with 1-year treatment outcome.MethodsWe trained machine learning models on regional GM measures to classify healthy controls (HC) (N = 289) from individuals at three stages of AN: underweight patients starting intensive treatment (N = 165, used as baseline), patients after partial weight-restoration (N = 115), and former patients after stable and full weight-restoration (N = 89). Alterations after weight-restoration were related to treatment outcome and characterized both anatomically and functionally.ResultsPatients could be classified from HC when underweight (ROC-AUC = 0.90) but also after partial weight-restoration (ROC-AUC = 0.64). Alterations after partial weight-restoration were more pronounced in patients with worse outcome and were not detected in long-term weight-recovered individuals, i.e. those with favorable outcome. These alterations were more pronounced in regions with greater functional connectivity, not merely explained by body mass index, and even increases in cortical thickness were observed (insula, lateral orbitofrontal, temporal pole).ConclusionsAnalyzing persistent multivariate brain structural alterations after weight-restoration might help to develop personalized interventions after discharge from inpatient treatment.
Differences in metacognitive functioning between obsessive–compulsive disorder patients and highly compulsive individuals from the general population
Authors: Hoven Monja , Rouault Marion , van Holst Ruth , Luigjes Judy 
Published: August 2023

AbstractBackgroundOur confidence, a form of metacognition, guides our behavior. Confidence abnormalities have been found in obsessive–compulsive disorder (OCD). A first notion based on clinical case–control studies suggests lower confidence in OCD patients compared to healthy controls. Contrarily, studies in highly compulsive individuals from general population samples showed that obsessive–compulsive symptoms related positively or not at all to confidence. A second notion suggests that an impairment in confidence estimation and usage is related to compulsive behavior, which is more often supported by studies in general population samples. These opposite findings call into question whether findings from highly compulsive individuals from the general population are generalizable to OCD patient populations.MethodsTo test this, we investigated confidence at three hierarchical levels: local confidence in single decisions, global confidence in task performance and higher-order self-beliefs in 40 OCD patients (medication-free, no comorbid diagnoses), 40 controls, and 40 matched highly compulsive individuals from the general population (HComp).ResultsIn line with the first notion we found that OCD patients exhibited relative underconfidence at all three hierarchical levels. In contrast, HComp individuals showed local and global overconfidence and worsened metacognitive sensitivity compared with OCD patients, in line with the second notion.ConclusionsMetacognitive functioning observed in a general highly compulsive population, often used as an analog for OCD, is distinct from that in a clinical OCD population, suggesting that OC symptoms in these two groups relate differently to (meta)cognitive processes. These findings call for caution in generalizing (meta)cognitive findings from general population to clinical samples.
Sticky criticism? Affective and neural responses to parental criticism and praise in adolescents with depression
Authors: van Houtum Lisanne A.E.M. , Wever Mirjam C.M. , van Schie Charlotte C. , Janssen Loes H.C. , Wentholt Wilma G.M. , Tollenaar Marieke S. , Will Geert-Jan , Elzinga Bernet M. 
Published: August 2023

AbstractBackgroundParent-adolescent interactions, particularly parental criticism and praise, have previously been identified as factors relevant to self-concept development and, when negative, to adolescent depression. Yet, whether adolescents with depression show aberrant emotional and neural reactivity to parental criticism and praise is understudied.MethodsAdolescents with depression (n = 20) and healthy controls (n = 59) received feedback supposedly provided by their mother or father in the form of negative (‘untrustworthy’), neutral (‘chaotic’), and positive (‘respectful’) personality evaluations while in an MRI-scanner. After each feedback word, adolescents reported their mood. Beforehand, adolescents had rated whether these personality evaluations matched their self-views.ResultsIn both groups, mood decreased after criticism and increased after praise. Adolescents with depression reported blunted mood responses after praise, whereas there were no mood differences after criticism. Neuroimaging analyses revealed that adolescents with depression (v. healthy controls) exhibited increased activity in response to criticism in the subgenual anterior cingulate cortex, temporal pole, hippocampus, and parahippocampal gyrus. Praise consistent with adolescents' self-views improved mood independent of depression status, while criticism matching self-views resulted in smaller mood increases in adolescents with depression (v. healthy controls). Exploratory analyses indicated that adolescents with depression recalled criticism (v. praise) more.ConclusionsAdolescents with depression might be especially attentive to parental criticism, as indexed by increased sgACC and hippocampus activity, and memorize this criticism more. Together with lower positive impact of praise, these findings suggest that cognitive biases in adolescent depression may affect how parental feedback is processed, and may be fed into their self-views.
Newman on emotion and cognition in the Grammar of Assent
Authors: Emrich Emma 
Published: August 2023

AbstractThis article considers the role of emotion in John Henry Newman's Grammar of Assent by distinguishing five different ways (or ‘models’) in which the emotions play a positive epistemic role in relation to cognition. The most important of these, the Cognitive-Emotion Model, offers a new account of Newman's crucial idea of real assent, one that stresses the primary role of the emotions in real assent rather than imagination. This model helps to explain the nature of real assent by highlighting Newman's portrayal of an emotional way of knowing an object that is personal or individual, incommunicable, vivid, and motive. In this study of the relations between emotion and cognition I hope to highlight unexplored aspects of the nature of real assent and the importance of the role of emotion in it and hope to show how Newman's epistemology offers a rich framework for exploring the positive epistemic contributions of the emotions.
You could be immaterial (or not)
Authors: Bailey Andrew M. 
Published: August 2023

AbstractMaterialists about human persons say that we are, and must be, wholly material beings. Substance dualists say that we are, and must be, wholly immaterial. In this article, I take issue with the ‘and must be’ bits. Both materialists and substance dualists would do well to reject modal extensions of their views and instead opt for contingent doctrines, or doctrines that are silent about those modal extensions. Or so I argue.
Severe COVID-19 classified by simple covid risk index is associated with higher levels of advanced oxidation protein products and 8-hydroxy 2 deoxyguanosine
Authors: Satała Joanna , Woźniak Agnieszka , Fabiś Mateusz , Gorzelak-Pabiś Paulina , Pawlos Agnieszka , Fabiś Jarosław , Broncel Marlena , Woźniak Ewelina 
Published: August 2023

Abstract
SARS-CoV-2 has become one of the most important and challenging medical research topics in recent years. The presence of endothelial dysfunction, immune thrombosis, and oxidative stress contributes to complications and requires more extended hospitalisation of patients. In this article, we focused on analysing the impact of oxidative stress on the severity of COVID-19 infection. The study group consisted of 72 patients with laboratory-confirmed SARS-CoV enrolled. The patients were divided into moderate and severe diseases according to the SCRI (Simple Covid Risk Index, including lymphocyte/D-dimer ratio). Using the ELISA kit, we determined the level of AOPP and 8-OHdG. Patients with severe COVID-19 had higher levels of both AOPP (P < 0.05) and 8-OHdG (P < 0.05) compared to patients with moderate disease. Albumin levels were significantly lower (P < 0.001), although fibrinogen (P < 0.01), D-dimer (P < 0.001), and TF (P < 0.05) levels were higher in severe patients than in moderate course. AOPP/Alb was also higher among severe patients (P < 0.05). Our data suggest a potential role for AOPP and 8-OHdG in predicting the outcome of SARS-CoV-2 patients. Elevated AOPP levels were associated with increased Dimer-D, TF, and vWF activity levels.
CROSS-REFERENCE BETWEEN LOGIC AND PSYCHOLOGY IN IBN SĪNĀ’S THEORY OF EXPERIENCE (TAǦRIBA)
Authors: Hoki Yu 
Published: August 2023

RésuméCet article démontre que la théorie de l’expérience (taǧriba) d’Ibn Sīnā nécessite une référence croisée entre la logique et la psychologie. Suivant la tradition linguistique basrane, il paraphrase les noms dérivés (ism muštaqq) dans la formule li-x y (« y appartient à x ») : par exemple, ʿālim (« savoir ») est paraphrasé en lahu ʿilm (« un acte de savoir lui appartient »). Sa théorie de l’expérience emploie cette formule pour arranger les phénomènes observés dans une certaine forme de syllogisme et décrire les fonctions des sens internes du cerveau. Ibn Sīnā arrange les phénomènes observés dans la formule li-x y ou la proposition dont un prédicat est un nom dérivé de y. En même temps, il soutient que le sens du souvenir est impliqué dans le processus de l’expérience. Le souvenir est un sens interne du cerveau, qui préserve maʿnā perçue par le sens de l’estimation. L’estimation consiste à percevoir maʿnā (y) qui est inhérente à un sujet (x), et à porter un jugement sur x en fonction de y. Ainsi, dans ce processus, l’analyse des noms dérivés range les phénomènes observés dans un ordre rationnel, et le sens interne établit la causalité entre l’appréhension et l’affirmation logique. L’article se termine par une discussion sur la relation de cette philosophie avec la médecine.