bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Economic Value of Plastic Waste Used as Paving Aggregate
Authors: Negi Ankit 
Published: May 2023

Solid waste, of which plastic waste is a significant part, is plentiful and often gets thrown away without being properly processed into a usable resource. Municipal plastic garbage disposal has increased dramatically, particularly in metropolitan areas, and this has a negative effect on the aesthetic quality of the environment. As a binding agent, plastic proved to be quite useful pliable asphalt mixtures made from bitumen. By limiting fracture formation and decreasing rainfall penetration, this effective strategy helps pavements tolerate greater temperatures, which would otherwise contribute to the development of potholes. Water seepage is decreased and crushing and abrasion parameters are increased in these pavements. Roads made of plastic would be a great solution to the problem of potholes caused by India's hot and humid environment, where temperatures often exceed 50°C and heavy rains cause havoc, leaving most roads in terrible condition.
Road paving, airport runways, parking garage floors, and other related construction applications often employ a composite material called bituminous concrete (BC). The final product is made by layering mineral aggregate with asphalt or bitumen (used as a binder), and then crushing the resulting mixture. The substantial distinction in daily and seasonal temperature, coupled with the ever-increasing volume of traffic comprised primarily of commercial vehicles, has put us in a precarious position that necessitates creative solutions for enhancing the characteristics and quality of the pavement through the implementation of some necessary modifications that must therefore satisfy the both strength and economic aspects.
When viewed from an environmental point of view, it is apparent that polythenes are a major contributor to air pollution. As it has been shown that polythenes are not biodegradable, finding a solution for waste polyethene has become an essential issue.
Longstanding giant frontoethmoidal mucocele with orbital and intracranial extension: challenges of surgical approach in a developing nation
Authors: Aliyu Daniel , Adeyeye Foluso M. , Mohammed Adamu D. , Iseh Kufre R. , Lasseini Ali 
Published: May 2023

Mucoceles of the paranasal sinuses are expansile, benign mucus filled epithelial lined cystic-like lesion resulting from chronic obstruction to sinus ostia. They erode bony walls by pressure and bony resorption with the frontal and ethmoid sinuses predominately affected. The expansile lesion can involve surrounding structures like the orbit, intracranium or nasopharynx. Diagnosis is based on history, examination and radiological assessment with Computerized tomography scan being the imaging of choice. Surgery is the mainstay of treatment and would require collaboration with the neurosurgeons or the ophthalmologist when it extends to the brain or orbit respectively. It can be done via an external approach, endoscopic approach or a combination of both. If left without intervention, it may cause morbidity and potential mortality due to its proximity to the brain and orbit. We report a rare case in our setting of a 65-year-old male farmer with a painless huge left sided cystic fronto-orbital swelling of 8 years that mimicked a benign orbital tumor. The mass was non-tender and not pulsatile measuring about 20×18 cm with normal visual acuity. Computed tomography (CT) scans of the brain and paranasal sinus revealed a large well-defined non-contrast enhancing homogenous lesion involving the left fronto-ethmoidal sinuses with orbital and intracranial extension as well as inferolateral displacement of the left eye globe. He was reviewed by the ENT surgeons, neurosurgeons and ophthalmologists and subsequently had frontoethmoidectomy via an external approach.
Efficacy of pre-operative submucosal injection of dexamethasone and triamcinolone acetonide on post-operative pain following endodontic treatment of teeth with irreversible pulpitis: A randomised clinical trial
Authors: Anand Pari , T Jaykumar , A Srirekha , C Champa , Shetty Ashwija , S Archana 
Published: May 2023

Post-endodontic pain is a challenge to clinicians. In this context the evidence for use of preoperative medication is not consistent. The study's objective is to assess the effects of dexamethasone and triamcinolone acetonide administered submucosally in single doses on postoperative pain following single-visit root canal treatment for teeth with symptomatic irreversible pulpitis. Thirty patients were randomly allocated in three groups. Group I received saline (control), Group II received dexamethasone (8mg) and Group III received triamcinolone acetonide (40mg) before endodontic treatment was initiated. Root canal treatment was performed in a single appointment for all the participants. Post-operative pain was assessed using Heft-Parker visual analogue scale (HP VAS). Comparison of HP VAS scores was done using Kruskal Wallis Test and Mann Whitney Test. There was no significant difference in the mean HP VAS scores between 3 groups at pre-op period (P=0.74). At 6,12 and 24h post-operative period the mean HP VAS scores in Group 2 and 3 was significantly lesser as compared to Group 1. Corticosteroid preoperative dosages led to a reduction in post endodontic pain after single visit root canal treatment of teeth with symptomatic irreversible pulpitis.
Strategi Pemberdayaan Kripik Tempe Melalui Media Sosial di Sukoharjo
Authors: Rahmawati Yunaita , Dhewantara Satria 
Published: May 2023

Pemberdayaan merupakan suatu upaya seseorang maupun kelompok masyarakat untuk meningkatkan dan kemandirian sehingga dapat mengaktualisasikan potensi yang sudah dimiliki. Untuk manusi yang berperan sebagai pelopor perubahan dimanapun keberadaannya. Sehingga, perlu adanya peningkatan kualitas hidup sumber daya manusia. Pelaksanaan kuliah pengabdian masyarakat daring dari rumah (KPM-DDR) ini bertujuan untuk guna menciptakan pemuda yang memiliki kemandirian dalam ekonomi, hal tersebut dapat diwujudkan melalui pemberdayaaan dalam mengembangkan usaha kripik tempe dan pelatihan pemasaran menggunakan media sosial. Potensi yang dimiliki dalam pengembangan kripik tempe diharapkan untuk mempermudah konsumen dalam melakukan pemesanan produk melalui media sosial, sehingga bisa meningkatkan nilai volume penjualan serta mampu bersaing di pasaran.
Empowerment is an effort of a person or community group to improve and be independent so that they can actualize their potential. For humans who act as pioneers of change wherever they exist. Thus, it is necessary to improve the quality of life of human resources. The implementation of the online community service lecture from home (KPM-DDR) aims to create youth who have independence in the economy, this can be realized through empowerment in developing tempeh chips business and marketing training using social media. The potential possessed in developing tempeh chips is expected to make it easier for consumers to order products through social media, so that they can increase the value of sales volume and be able to compete in the market.
Penerapan Inklusi Keuangan dalam Pengembangan UMKM di Bank Pembiayaan Rakyat Syariah Sukowati Sragen (Studi Komparasi Sebelum Pandemi dan Saat Pandemi)
Authors: Syafa Tasya Wahyuleananda  , Faruq Ahmad Futaqi  
Published: May 2023

Abstract: Financial inclusion ensures that vulnerable groups of people can obtain adequate bank and credit financial services in a timely manner and at affordable costs. The number of MSMEs experienced a decline in sales and difficulties in terms of capital. Lack of capital for MSMEs, which only rely on very limited personal capital, while loan capital from financial institutions is difficult to obtain because the requirements are too complicated and cannot be met. The purpose of this study was to analyze the comparison of the mechanism, effectiveness and constraints of implementing financial inclusion in the development of MSMEs at BPRS Sukowati Sragen before and during the pandemic. This study uses a qualitative-comparative research approach. The results of this study conclude that the form of financial inclusion at BPRS Sukowati Sragen is that the bank continues to accelerate financing to MSME actors, whether affected by COVID or not. Comparison of the effectiveness of implementing financial inclusion at the Sukowati Sragen BPRS, seen from community access, it can be said to be more effective before the pandemic because the implementation before the pandemic carried out socialization activities, market raids, product exhibitions and mobile cash by going directly to the field, while during the pandemic the activities were limited. . However, in its implementation there are still obstacles such as the absence of a digital platform.
Keywords: Financial Inclusion, MSMEs, Pandemic, BPRS

Abstrak: Inklusi keuangan memastikan bahwa kelompok masyarakat yang rentan dapat memperoleh layanan keuangan bank dan kredit yang memadai secara tepat waktu dan biaya terjangkau. Banyaknya UMKM yang mengalami penurunan penjualan dan kesulitan dalam hal permodalan. Kurangnya permodalan UMKM yang hanya mengandalkan modal pribadi yang sangat terbatas sedangkan modal pinjaman dari lembaga keuangan sulit diperoleh karena persyaratan yang terlalu rumit dan tidak bisa dipenuhi. Tujuan penelitian ini adalah untuk menganalisis perbandingan mekanisme, efektivitas dan kendala penerapan inklusi keuangan dalam pengembangan UMKM di BPRS Sukowati Sragen sebelum dan saat pandemi. Penelitian ini menggunakan pendekatan penelitian kualitatif-komparatif. Hasil penelitian ini menyimpulkan bahwa wujud inklusi keuangan di BPRS Sukowati Sragen adalah bank terus mengakselerasi pembiayaan ke para pelaku UMKM baik yang terdampak covid maupun tidak. Perbandingan efektifitas penerapan inklusi keuangan di BPRS Sukowati Sragen dilihat dari akses masyarakat bisa dikatakan lebih efektif pada saat sebelum pandemi karena penerapan sebelum pandemi kegiatan sosialisasi-sosialisasi, grebek pasar, pameran produk dan kas keliling dilakukan dengan terjun langsung ke lapangan sedangkan saat pandemi kegiatan dilakukan terbatas. Namun dalam penerapannya masih terdapat kendala seperti belum adanya platform digital.
Kata Kunci: Inklusi Keuangan, UMKM, Pandemi, BPRS
Efektivitas Pemberdayaan Zakat Produktif di Laboratorium Zakat, Infak, Sedekah, dan Wakaf IAIN Ponorogo
Authors: Afif Izam Taufik  , Ajeng Wahyuni  
Published: May 2023

The main objective of this research is to analyze the effectiveness of productive zakat empowerment in goats' cattle for improving community welfare. The research type is field research using an inductive qualitative approach. The research was conducted in the laboratory of zakat, infaq, alms, and waqf of IAIN Ponorogo with data collection techniques using interviews, observations, and documentation. The results of this study show that (1) in the empowerment program, productive zakat funds use conventional productive forms; (2) the effectiveness of productive zakat empowerment in goats' cattle can already be said to be effective as it is in accordance with the indicators put forward by Budiani (2009); (3) there are obstacles in implementing the productive zakat empowerment in goats' cattle, including technical constraints, financial constraints, and market constraints.
Tujuan utama penelitian ini adalah untuk menganalisis efektivitas pemberdayaan zakat produktif ternak kambing dalam menyejahterakan masyarakat. Jenis penelitian yang digunakan, yaitu penelitian lapangan (field reseach) dengan pendekatan kualitatif induktif. Penelitian dilakukan di Laboratorium Zakat, Infak, Sedekah, dan Wakaf IAIN Ponorogo dengan teknik pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Hasil penelitian ini menunjukkan sebagai berikut: (1) dalam program pemberdayaan, dana zakat produktif menggunakan bentuk produktif konvensional; (2) efektivitas pemberdayaan zakat produktif ternak kambing sudah dapat dikatakan efektif karena sesuai dengan indikator-indikator yang dikemukakan oleh Budiani (2009); (3) terdapat kendala dalam pelaksanaan pemberdayaan zakat produktif ternak kambing, di antaranya yaitu, kendala teknis, kendala finansial, dan kendala pasar.
Generation of three-dimensional skeletal muscle tissue as cultured meat from stable pig epiblast stem cells
Authors: Zhu Gaoxiang , Gao Dengfeng , Li Linzi , Yao Yixuan , Wang Yingjie , Zhi Minglei , Zhang Jinying , Chen Xinze , Zhu Qianqian , Gao Jie , Chen Tianzhi , Zhang Xiaowei , Wang Tong , Cao Suying , Ma Aijin , Feng Xianchao , Han Jianyong 
Published: May 2023

Abstract
Cultured meat (CM) production has emerged as a breakthrough technology for the global food industry, with the potential to reduce challenges associated with environmental sustainability, global public health, animal welfare, and competition for food between humans and animals. The muscle stem cell lines currently used for CM production cannot be passaged in vitro for extended periods of time. Here, we successfully developed a directional differentiation system of porcine pregastrulation epiblast stem cells (pgEpiSCs) with stable cellular features and achieved serum-free myogenic differentiation of the pgEpiSCs. The pgEpiSCs-derived skeletal muscle progenitor cells and skeletal muscle fibers show typical muscle cell characteristics and display skeletal muscle transcriptional features during myogenic differentiation. Importantly, we further established a three-dimensional differentiation system for shaping cultured tissue by screening plant-based edible scaffolds of non-animal origin, followed by the generation of pgEpiSCs-derived CM. These advances provide a novel technical approach for the development of CM.
Assessment of COVID-19 Numbers by Using Fisher Transform Indicator
Authors: Nutku Ferhat 
Published: May 2023

Abstract
New cases, new deaths, new deaths per new cases numbers belonging to COVID-19 pandemic investigated via open, high, low, close candlesticks and Fisher transform indicator. Candlestick plots, accompanied by crossovers in the Fisher transform indicator, facilitate the determination of the beginning of upward and downward trends in numbers, clearly and in a timely manner. It has been shown that an increase in the total number of peaks over time, in both smoothed candlestick data and in the Fisher transform indicator, can indicate the temporary or persistent diminishing of a pandemic.
Comparative study of Discharge Estimation using Non-Parametric and Parametric Methods
Authors: SHARMA ABHISHEK , Shankar Vijay , Thakur Praveen Kumar 
Published: May 2023

Abstract
Runoff estimation from a watershed is of utmost importance for various hydrologic and hydraulic purposes. The present study aims to evaluate various parametric and non-parametric methods of discharge estimation for the Gambhar watershed in the state of Himachal Pradesh, India. The study employed Artificial Neural Network (ANN) as a non-parametric and statistical modelling and the Green-Ampt (GA) infiltration model as parametric methods. The Meteorological data for the duration of twenty years was procured from Indian Meteorological Department (IMD). By employing the GA infiltration model, the cumulative infiltration and subsequently the runoff was calculated for different intensities while lag time was assessed using ArcGIS. The collected field point data for various soil infiltration parameters was spatially interpolated. The cumulative distribution function (CDF) of discharge were generated with a confidence limit of 95% using statistical modelling. The root mean square error (RMSE) and coefficient of determination (R2) were employed to determine the best ANN architecture. On the basis of the qualitative and quantitative comparative evaluation, the study establishes the efficacy of ANN method over parametric methods i.e., GA and statistical modelling, in discharge estimation with values of average relative error (ARE) & Nash Sutcliffe Efficiency (NSE) coefficient as 0.15 & 0.91 respectively.
Ecological and statistical models to configure flow regime for environment benefit in a regulated river
Authors: Atazadeh Ehsan , Gell Peter , Mills Keely , Barton Andrew , Newall Peter 
Published: May 2023

AbstractEcological and statistical models were developed using freshwater algal assemblages to assess water quality and ecological health of a regulated river. These models were used to inform configuration of flows to maintain or improve environmental conditions of the waterway whilst meeting consumptive water supply commitments. The flow regime of the MacKenzie River, western Victoria, Australia, has been substantially modified since the construction of a water supply reservoir on its upper reach in 1887. Water is withdrawn at several locations downstream of the reservoir, creating a substantially modified flow regime, impacting key environmental values of the river. To assess the impact of the different flow regimes on river health and ecosystem function, ten sites were repeatedly sampled along the river between February 2012 and April 2014. Physical and chemical characteristics of water, including pH, temperature, turbidity, electrical conductivity, dissolved oxygen, total nitrogen, total phosphorous, cations and anions were measured. Biological properties of the algal periphyton communities, including dry mass, ash-free dry mass, chlorophyll-aconcentration and species composition were also measured. Exploration of the algal assemblage and water chemistry data using the computationally unconstrained ordination technique such as principal component analysis principal component analysis (PCA), correspondence analysis (CA), detrended correspondence analysis (DCA) and canonical correspondence analysis (CCA) indicated two strong gradients in the data sets. Furthermore, the quantitative ecosystem response models have been developed as the prototype tool to assist in the future configuration of flows in this river. The empirical data and models showed the lower reaches of the river to be in poor condition under low flows, but this condition improved under flows of 35 ML/day, as indicated by the reduction in green algae and cyanobacteria and improvement. Finally, the results are presented to tailor discharge and duration of water volume by amalgamation of consumptive and environmental flows to improve the condition of the stream thereby supplementing the flows dedicated to environmental outcomes.
Diversity analysis of endophytic bacteria community in ramie
Authors: Xiang-ping Sun , Meng-ya Chen , Yong-qiang Tu , Liang-bing Zeng , Jian-jun Li , Li Yan , Chun-Wu Nie , Chuan-ru Wen 
Published: May 2023

Abstract
Ramie [Boehmeria nivea (L.) Gaud], which are known as “China grass”, which is famous for its excellent fibrous properties, such as high tensile strength, excellent thermal conductivity, silky luster, ventilation, moisture absorption and antibacterial properties. Endophytes can also be beneficial to their host by producing a range of natural products that could be harnessed for potential use in medicine, agriculture or industry. In the study, more than 90% of all ramie plants are grown in China. Research on plant microbiomes has accumulated a large amount of sequencing data and abundant information, indicating the diversity and richness of different microbial communities in the rhizosphere, leaf boundary, seed, and germ layer of many plants. In our study, the population density of endophytic bacteria is the highest in the root tissue, taken together, plant endophyte types are very rich. In addition, they have a special way of survival. Therefore, plant endophyte is more important for the development of medicinal resources. However, on the whole, there are relatively few studies on plant endophytes, and the scope of research is relatively narrow, and plant endophytes have more important scientific significance. Therefore, attention should be paid to their research. This paper expects to provide support for the development of cash crop, especially ramie industry in the future through the sequencing of metagenome.
Uncovering Hidden Risk Profile Phenotypes of Substance Use Among Canadian Adolescents via Cluster Analysis of COMPASS Data
Authors: Yang Yang , Butt Zahid , Leatherdale Scott , Wong Alexander , Chen Helen 
Published: May 2023

Abstract
This study utilized a longitudinal health survey to identify sub-phenotypes of behavioral risk profiles related to youth substance use. We analyzed 8824 Canadian secondary school students who completed COMPASS questionnaires in 2016/17 and were followed up until 2018/19. The fuzzy clustering algorithm was used to identify four sub-phenotypes of risk profiles, including low-risk, medium-low-risk, medium-high-risk, and high-risk subgroups. The study found that the mean scores of health risk behaviors within each subgroup increased across the three waves, indicating a rising risk of health behaviors over time. The results confirm heterogeneity in the prevalence and characteristics across the subgroups. These findings can help school program managers and policymakers develop targeted interventions to reduce substance use among at-risk individuals and improve youth health behaviors. By identifying at-risk groups, stakeholders can develop effective preventive measures against addictive behaviors in school settings. The study results offer evidence to support the development of risk reduction interventions for youth substance use and ultimately improve youth health behaviors.
MiR-326 mediated overexpression of NFIB offsets TGF-β induced Epithelial to Mesenchymal Transition and reverses lung fibrosis
Authors: Pattnaik Bijay , Negi Vinny , Chaudhuri Rituparna , Desiraju Koundinya , Gheware Atish , Prakash YS , Guleria Randeep , Ghosh Balaram , Agrawal Anurag , Ahmad Tanveer 
Published: May 2023

Abstract
Idiopathic Pulmonary Fibrosis (IPF) is a progressively fatal and incurable disease characterized by the loss of alveolar structures, increased epithelial-mesenchymal transition (EMT), and aberrant tissue repair. In this study, we investigated the role of Nuclear Factor I-B (NFIB), a transcription factor critical for lung development and maturation, in IPF. Using both human lung tissue samples from patients with IPF, and a mouse model of lung fibrosis induced by bleomycin, we showed that there was a significant reduction of NFIB both in the lungs of patients and mice with IPF. Furthermore, our in vitro experiments using cultured human lung cells demonstrated that the loss of NFIB was associated with the induction of EMT by transforming growth factor beta (TGF-β). Knockdown of NFIB promoted EMT, while overexpression of NFIB suppressed EMT and attenuated the severity of bleomycin-induced lung fibrosis in mice. Mechanistically, we identified post-translational regulation of NFIB by miR-326, a miRNA with anti-fibrotic effects that is diminished in IPF. Specifically, we showed that miR-326 stabilized and increased the expression of NFIB through its 3'UTR target sites for Human antigen R (HuR). Moreover, treatment of mice with either NFIB plasmid or miR-326 reversed airway collagen deposition and fibrosis. In conclusion, our study emphasizes the critical role of NFIB in lung development and maturation, and its reduction in IPF leading to EMT and loss of alveolar structures. Our study highlights the potential of miR-326 as a therapeutic intervention for IPF.