bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breast and prostate cancer screening rates by cognitive status in US older adults
Authors: Schoenborn Nancy L. , Cidav Tom , Boyd Cynthia M. , Pollack Craig E. , Sekhon Vishaldeep Kaur , Yasar Sevil 
Published: January 2023

AbstractIntroductionFor most older adults with dementia, the short‐term harms and burdens of routine cancer screening likely outweigh the delayed benefits. We aimed to provide a more updated assessment of the extent that US older adults with dementia receive breast and prostate cancer screenings.MethodsUsing the Health and Retirement Study (HRS) Wave 12 (2014–2015) linked to Medicare, we examine rates of breast and prostate cancer screenings in adults 65+ years by cognitive status. We used claims data to identify eligibility for screening and receipt of screening. We used a validated method using HRS data to define cognitive status.ResultsThe analytic sample included 2439 women in the breast cancer screening cohort and 1846 men in the prostate cancer screening cohort. Average ages were 76.8 years for women and 75.6 years for men, with 9.0% and 7.6% with dementia in each cohort, respectively.Among women with dementia, 12.3% were screened for breast cancer. When stratified by age, 10.6% of those 75+ and have dementia were screened for breast cancer. When stratified by predicted life expectancy, 10.4% of those with predicted life expectancy of <10 years and have dementia were screened for breast cancer.Among men with dementia, 33.9% were screened for prostate cancer. When stratified by age, 30.9% of those 75+ and have dementia were screened for prostate cancer. When stratified by predicted life expectancy, 34.4% of those with predicted life expectancy of <10 years and have dementia were screened for prostate cancer.Using multivariable logistic regression, dementia was associated with lower odds of receiving breast cancer screening (OR 0.36, 95% CI 0.23–0.57) and prostate cancer screening (OR 0.58, 95% CI 0.36–0.96).DiscussionOur results suggest potential over‐screening in older adults with dementia. Better supporting dementia patients and caregivers to make informed cancer screening decisions is critical.
Thermodynamic rarity of electrical and electronic waste: Assessment and policy implications for critical materials
Authors: Campbell‐Johnston Kieran , Roos Lindgreen Erik , Mondello Giovanni , Gulotta Teresa Maria , Vermeulen Walter J. V. , Salomone Roberta 
Published: January 2023

AbstractThe strategic relevance of extracting raw materials from waste from electrical and electronic equipment (WEEE) in the EU is increasing due to value chain risks caused by geopolitical instability, accessibility of specific minerals, and decreasing reserves due to growing extraction rates. This article examines the quantities of so‐called critical raw materials (CRMs) originating within WEEE streams from a depletion perspective. Presently, current recycling targets are based solely on mass collection and recycling rates. We examine the potential limitations of this approach using an exergy‐based indicator named thermodynamic rarity. This indicator represents the exergy costs needed for producing materials from the bare rock to market. The case of Italy is used to explore the application of the indicator at the macro (national) and micro (company) level for the product categories “small electronics” and “screens and monitors.” Our estimations show significant differences between the mass and rarity of materials within Italian WEEE streams. While iron accounts for more than 70% of the weight of the product categories analyzed, it accounts for less than 15% of the rarity. Similarly, several CRMs with a small mass have a higher rarity value, for example, tungsten with less than 0.1% of the mass and over 6% of the rarity. The policy context is reflected upon, where it is argued that thermodynamic rarity can provide novel insights to support end‐of‐life WEEE decision‐making processes, for example, target development and recycling standards setting to help prioritize material monitoring and recovery options.
Implementation strategies to promote compassionate nursing care of complex patients: An exploratory sequential mixed methods study
Authors: Younas Ahtisham , Porr Caroline , Maddigan Joy , Moore Julia , Navarro Pablo , Whitehead Dean 
Published: January 2023

AbstractIntroductionIndividuals with multiple physical and, or, mental health issues and, or, drug‐related problems are known as complex patients. These patients are often recipients of poor‐quality care. Compassionate nursing care is valuable to promote better care experiences among this patient population. Implementation strategies should be designed to enhance compassionate nursing care delivery. The study aimed to gain understanding of barriers to compassionate care delivery to propose implementation to promote compassionate nursing care of complex patients.DesignAn exploratory sequential mixed methods study was conducted.MethodsPhase 1 was the qualitative component during which 23 individuals with multimorbidities were interviewed for exploring their perceptions of barriers to compassionate nursing care. The barriers were integrated with implementation science frameworks using the building technique during phase 2 to develop a Q‐sort survey of implementation strategies for phase 3. Nurses, nurse managers, health care administrators, policymakers, and compassionate care experts responded to the survey by ranking the 21 implementation strategies, out of which five met the Q‐factor analysis criteria.ResultsParticipant‐perceived barriers to nurse compassion could be categorized under knowledge, intentions, skills, social influences, behavioral regulation, reinforcement, emotion, and environmental context and resources. The five highest‐ranked strategies included facilitation, consultation with stress experts, involvement of patients and families, modeling compassion through shadowing, and utilizing implementation teams.ConclusionsEnablement and modeling were the integration functions represented by the highest‐ranked implementation strategies. Enabling nurses to provide compassionate care through emotional support and mental health counseling, and, modeling compassion and compassionate care through shadowing were recommended and rated as highly relevant by the majority of stakeholders.Clinical RelevanceEnhancing nurses compassionate behaviors toward complex patients requires facilitating them in enacting compassion in practice through modeling and support from organizations and nurse managers.
EGCG inhibits hypertrophic scar formation in a rabbit ear model
Authors: Song Yajuan , Wang Tong , Yang Liu , Wu Junzheng , Chen Lin , Fan Xiao , Zhang Zhe , Yang Qing , Yu Zhou , Song Baoqiang 
Published: January 2023

AbstractObjectiveHypertrophic scarring is a common skin fibro‐proliferative disease, but currently there has no satisfactory drugs for anti‐scar treatments. Previous study showed that epigallocatechin gallate (EGCG), the main catechin in green tea, improved wound healing and tissue fibrosis in both rats and mice. In the present study, the therapeutic effects of EGCG on hypertrophic scar were analyzed using a rabbit ear hypertrophic scar model.MaterialsA rabbit ear model of hypertrophic scarring was used. DMSO, 0.5 mg EGCG/wound, 1.0 mg EGCG/wound or triamcinolone were injected subcutaneously once a week for 4 weeks. The scar elevation index (SEI) was measured using HE staining images, the collagen fibers were examined by Masson’ trichrome staining images, and the number of capillaries in hypertrophic scar were calculated by CD31 staining images. The mRNA levels in the scar tissues were detected by quantitative real‐time polymerase chain reaction (qRT‐PCR).ResultsGross observation and histological evaluation showed the inhibitory effects of EGCG on hypertrophic scar formation at both doses, and decreased scar height and SEI were detected. EGCG also attenuated the mean collagen area fraction and decreased the number of capillaries in scar tissues. qRT‐PCR revealed that EGCG significantly inhibited the mRNA expression of TGF‐β1, Col I, Col III, α‐SMA, and eNOS.ConclusionEGCG may serve as a useful candidate therapeutic drug for hypertrophic scar via inhibiting fibrotic gene expression and suppressing angiogenesis.
An improved human skin explant culture method for testing and assessing personal care products
Authors: Zhou Linli , Ji Wei , Dicolandrea Teresa , Finlay Deborah , Supp Dorothy , Boyce Steven , Wei Karl , Kadekaro Ana Luisa , Zhang Yuhang 
Published: January 2023

AbstractBackgroundCultured human skin models have been widely used in the evaluation of dermato‐cosmetic products as alternatives to animal testing and expensive clinical testing. The most common in vitro skin culture approach is to maintain skin biopsies in an airlifted condition at the interface of the supporting culture medium and the air phase. This type of ex vivo skin explant culture is not, however, adequate for the testing of cleansing products, such as shampoos and body washes. One major deficiency is that cleansing products would not remain confined on top of the epidermis and have a high chance of running off toward the dermal side, thus compromising the experimental procedure and data interpretation.Materials and MethodsHere, we describe an improved ex vivo method for culturing full‐thickness human skin for the effective testing and evaluation of skin care products by topical application.ResultsThis newly developed ex vivo human skin culture method has the ability to maintain healthy skin tissues for up to 14 days in culture. Importantly, the model provides a quick and safe way to evaluate skin care products at different time points after single or repetitive topical applications using a combined regimen of leave‐on and wash‐off. We found that the results obtained using the new skin culture method are reproducible and consistent with the data collected from clinical testing.ConclusionOur new ex vivo skin explant method offers a highly efficient and cost‐effective system for the evaluation and testing of a variety of personal care products and new formulations.
Relationship between out‐of‐facility deliveries and distance and travel time to delivery facilities in Hokkaido, Japan: An ecological study
Authors: Saito Yoshihiro , Asakura Toshiaki , Takashi Kimura , Umazume Takeshi , Watari Hidemichi , Tamakoshi Akiko 
Published: January 2023

AbstractAimThis study aimed to investigate the relationship between the distance and travel time from each municipality to the nearest delivery facilities in the other municipalities and the frequency of out‐of‐facility deliveries in Hokkaido.MethodsVital statistics from 2016 to 2020 were used. For municipalities without delivery facilities, the distance and travel time from the town office of each municipality to the nearest delivery facility was measured using Google maps. Negative binomial regression with an offset term was used to calculate the relative risks (RRs) and 95% confidence intervals (CIs) of out‐of‐facility delivery for distance (<30, 30–59, ≥60 km), and travel time by car (<30, 30–59, and ≥60 min) from the town office to the nearest delivery facility compared with the presence of delivery facilities.ResultsThe overall rate of out‐of‐facility deliveries in Hokkaido was 2.1‰; in municipalities with delivery facilities, 1.8‰, and in municipalities without delivery facilities, 3.1‰. The adjusted RRs (95% CIs) for out‐of‐facility deliveries were significantly higher in municipalities with less than 30 km and travel time of less than 30 min to delivery facilities, 2.63 (1.34–5.17) and 2.76 (1.36–5.58), respectively, compared to municipalities with delivery facilities. However, the adjusted RR of out‐of‐facility delivery for municipalities ≥30 km was higher, although the difference was not significant.ConclusionsEven in municipalities with a distance to delivery facilities of less than 30 km or travel time of less than 30 min, we should keep in mind the occurrence of out‐of‐facility deliveries.
Anti‐Judaism versus anti‐Semitism: The racialization of Jews in late antiquity
Authors: Binyam Yonatan 
Published: January 2023

AbstractThis article interrogates the arbitrary distinctions made between “anti‐Judaism” and “anti‐Semitism” by contextualizing the treatment of Jews in Roman late antiquity within the broader framework of premodern critical race studies. It illustrates the value of employing models such as racialization and monstrification when reconstructing the various iterations of anti‐Jewish prejudice that populate the long history of Christianity. More specifically, it outlines the modes of racialization utilized in two fourth‐century Christian writings: Eusebius's two‐part apology and the Pseudo‐Hegesippus. While Eusebius's work serves as an example of the racialization of Jews through ethnographic mythmaking, the so‐called Pseudo‐Hegesippus demonstrates the use of monstrification in the service of creating an affective culture of fear and hatred toward Jews. Such examples of Christian race‐making in late antiquity contribute to the task of tracing the developments of premodern race beyond the medieval period and disrupts the arbitrary and limiting distinctions made between anti‐Judaism and anti‐Semitism.
Impact of direct‐acting antiviral treatment on health utility in patients with chronic hepatitis C in hospital and community settings
Authors: Wong William W. L. , Wong Josephine , Bremner Karen E. , Saeed Yasmin , Mason Kate , Phoon Arcturus , Martel‐Laferrière Valérie , Bruneau Julie , Feld Jordan J. , Feng Zeny , Baguley Elizabeth , Lee Samuel S. , Powis Jeff , Krahn Murray D. 
Published: January 2023

AbstractBackgroundDirect‐acting antiviral agents (DAAs) have transformed chronic hepatitis C (CHC) treatment. Continued affordable access to DAAs requires updated cost‐effectiveness analyses (CEA). Utility is a preference‐based measure of health‐related quality of life (HRQoL) used in CEA. This study evaluated the impact of DAAs on utilities for patients with CHC in two clinical settings.MethodsThis prospective longitudinal study included patients aged ≥18 years, diagnosed with CHC and scheduled to begin DAA treatment, from two tertiary care hospital clinics and four community clinics in Toronto, Calgary, and Montreal. Patients completed two utility instruments (EQ‐5D‐5L and Health Utilities Index 2/3 (HUI2/3)) before treatment, 6 weeks after treatment initiation, and 12 weeks and 1 year after treatment completion. We measured utilities for all patients, and for hospital‐based and community‐based groups.ResultsBetween 2017 and 2020, 209 patients (126 hospital‐based, 83 community‐based; average age 53 years; 65% male) were recruited, and 143 completed the 1‐year post‐treatment assessment. Pre‐treatment, utilities were (mean ± standard deviation) 0.77 ± 0.21 (EQ‐5D‐5L), 0.69 ± 0.24 (HUI2) and 0.58 ± 0.34 (HUI3). The mean changes at 1‐year post‐treatment were 0.035, 0.038 and 0.071, respectively. While utilities for hospital‐based patients steadily improved, utilities for the community‐based cohort improved between baseline and 12‐weeks post‐treatment, but decreased thereafter.DiscussionThis study suggests that utilities improve after DAA treatment in patients with CHC in a variety of settings. However, community‐based patients may face challenges related to comorbid health and social conditions that are not meaningfully addressed by treatment. Our study is essential for valuing health outcomes in CHC‐related CEA.
Use of designing for behaviour change framework in identifying and addressing barriers to and enablers of animal source feeding to children ages 8–23 months in Bandarban Hill District in Bangladesh: Implications for a nutrition‐sensitive agriculture programme
Authors: Kalam Md Abul , Asif Chowdhury A. A. , Stormer Ame , Bishop Treena , Jackson‐deGraffenried Meredith , Talukder Aminuzzaman 
Published: January 2023

AbstractInadequate diet quality is a cause of undernutrition among children 6–23 months of age in Bangladesh, particularly in remote and isolated areas such as Bandarban District. Feeding animal source foods can help to combat stunting and wasting problems among children, but it may not be accessible or acceptable. A barrier analysis using the Designing for Behavior Change Framework was conducted in Bandarban district with participants from 4 ethnic groups, to explore potential barriers and key motivators by examining 12 behavioural determinants of consumption of animal‐source food in complementary feeding for children 8–23 months. Data were collected from 45 mothers of children 8–23 months, who provided animal‐source foods to their children (doers), and from 45 mothers who did not (non‐doers), for a total of 90 interviews. Nine determinants were statistically significantly different between doers and non‐doers as follows: self‐efficacy, positive consequences, negative consequences, social norms, access, reminders, perceived risk, perceived severity and perceived action efficacy. Nearby access to purchase animal‐source foods, rearing poultry or livestock at home and the support of household and community members are enablers to feeding animal‐source food. In contrast, these same factors are barriers for non‐doers. The lack of money to spend on animal‐source foods is also a barrier. An integrated nutrition‐sensitive and gender‐transformative animal‐based food production, and inclusive market programme could increase access to meat and eggs at the household level, increase opportunities to earn income and support gender‐equitable household workloads and decision‐making for optimal child feeding.
A review on health and well‐being at work: More than stressors and strains
Authors: Sonnentag Sabine , Tay Louis , Nesher Shoshan Hadar 
Published: January 2023

AbstractResearch in psychology and organizational behavior has made substantial progress in understanding what affects employee health and well‐being. In this review article, we describe how characteristics of individual workplaces (job resources, job stressors), interpersonal and teamwork factors, leadership, and specific employee behaviors contribute to health and well‐being. We summarize findings from intervention research and discuss how health and well‐being, in turn, predict perceived work characteristics and behavior at work. We highlight emerging topics in the field (job‐related health and well‐being during the COVID‐19 pandemic, technology‐enabled connectivity to work, micro‐interventions, dynamism in health and well‐being). We include a cross‐cultural and international perspective and address issues related to diversity and inclusion in organizations. We provide suggestions on how research can proceed in the future and point to practical implications that can improve employee health and well‐being.
Mineralogical and sulfur isotopic characteristics of Archean greenstone belt‐hosted gold mineralization at the Tau deposit of the Mupane gold mine, Botswana
Authors: Seaba Onameditse Lulu , Imai Akira , Yonezu Kotaro , Baliki Kemmonye 
Published: January 2023

AbstractThe Mupane gold deposit, which is one of the numerous gold occurrences in the Tati Greenstone Belt in the northeastern part of Botswana, consists of four orebodies, namely Tau, Tawana, Kwena, and Tholo deposits. The present research, which focuses on the genesis of the Tau deposit, was based on ore petrography, mineral chemistry of sulfides, and sulfur isotope data. Mineralogical characteristics of the host rocks indicate that banded iron formation at the Tau deposit includes iron oxides (magnetite), carbonates (siderite and ankerite), silicates (chlorite and amphibole), and sulfides (arsenopyrite and pyrrhotite). The deposit features arsenopyrite‐rich zones associated with biotite‐chlorite veins, which are indicative of the precipitation of arsenopyrite concomitant with potassic alteration. The replacement of magnetite by pyrrhotite in some samples suggests that sulfidation was likely the dominant gold precipitation mechanism because it is considered to have destabilized gold‐thiocomplexes in the ore‐forming fluids. Based on textural relationships and chemical composition, arsenopyrite is interpreted to reflect two generations. Arsenopyrite 1 is possibly early in origin, sieve textured with abundant inclusions of pyrrhotite. Arsenopyrite 1 was then overgrown by late arsenopyrite 2 with no porous textures and rare inclusions of pyrrhotite. Gold mineralization was initiated by focused fluid flow and sulfidation of the oxide facies banded iron formation, leading to an epigenetic gold mineralization. The mineralogical assemblages, textures, and mineral chemistry data at the Tau gold deposit revealed two‐stage gold mineralizations commencing with the deposition of invisible gold in arsenopyrite 1 followed by the later formation of native gold during hydrothermal alteration and post‐depositional recrystallization of arsenopyrite 1. Laser ablation inductively coupled plasma mass spectrometric analysis of arsenopyrite from the Tau deposit revealed that the hydrothermal event responsible for the formation of late native gold also affected the distribution of other trace elements within the grains as evidenced by varying trace elements contents in arsenopyrite 1 and arsenopyrite 2. The range of δ34S of gold‐bearing assemblages from the Tau deposit is restricted from +1.6 to +3.9‰, which is typical of Archean orogenic gold deposits and indicates that overall reduced hydrothermal conditions prevailed during the gold mineralization process at the Tau deposit. The results from this study suggest that gold mineralization involved multi‐processes such as sulfidation, metamorphism, deformation, hydrothermal alteration, and gold remobilization.
Social support from weak ties: Insight from the literature on minimal social interactions
Authors: Moreton Joshua , Kelly Caitlin S. , Sandstrom Gillian M. 
Published: January 2023

AbstractWhen people face difficult life events, such as cancer or bereavement, they fare better when they receive support. These “experiencers” are likely to seek and receive support from a wide range of people, from close others to acquaintances. Indeed, the social support literature has long acknowledged the value of having a diverse support network. Research suggests that experiencers often perceive “weak ties” (i.e., acquaintances) as sources of support, and that experiencers sometimes prefer to get support from weak ties rather than strong ties. Providing support can be challenging for all kinds of supporters, however weak ties may be more likely than strong ties to allow worries about their inability to provide effective support to stop them from providing any support at all, thus depriving experiencers of opportunities for additional support. In this paper, we focus on the fact that often the provision of support occurs via a social interaction. We draw on the social psychology literature on minimal social interactions to suggest reasons why potential weak tie supporters might doubt their ability to provide effective support, and to generate advice to encourage potential supporters to reach out. Finally, we suggest future areas of research, with the ultimate goal of helping to expand the support that is available for people experiencing difficult life events.