bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do personality characteristics predict future alcohol problems after considering current demography, substance use, and alcohol response?
Authors: Schuckit Marc A. , Smith Tom L. , Danko George , Bucholz Kathleen K. , Hesselbrock Victor , Hesselbrock Michie , Kuperman Samuel , Kramer John , Nurnberger John I. , Lai Dongbing , Chan Grace , Kamarajan Chella , Kuo Sally , Dick Danielle M. , Tear Jake , Mendoza Lee Anne , Edenberg Howard J. , Porjesz Bernice 
Published: April 2023

AbstractBackgroundSeveral personality traits predict future alcohol problems but also relate to demographic and substance‐related variables that themselves correlate with later adverse alcohol outcomes. Few prospective studies have evaluated whether personality measures predict alcohol problems after considering current demographic and substance‐related variables.MethodsData from 414 drinkers without alcohol use disorder (AUD) from the Collaborative Study on the Genetics of Alcoholism (average age 20, 44% male) were followed over an average of 9 years. Time 1 (baseline) demography, AUD family history (FH), substance use and problems, and psychiatric histories were gathered using a standardized interview; the Level of Response (LR) to alcohol was measured by the Self‐Report of the Effects of alcohol (SRE) questionnaire; and seven personality dimensions were extracted from the NEO Five‐Factor Personality, Barratt, and Zuckerman scales. Analyses involved product–moment correlations of each baseline measure with the highest number of DSM‐IV AUD criteria endorsed in any follow‐up period, and hierarchical regression analyses evaluated whether the personality domains added significantly to the prediction of the outcome after adjusting for other baseline variables.ResultsSignificant correlations with the outcome were observed for baseline age, sex, length of follow‐up, AUD family history, past cannabis use, and all alcohol‐related baseline variables, including SRE‐based LR, but not prior mood or anxiety disorders. All personality characteristics except extraversion also correlated with outcomes. A hierarchical regression analysis that included all relevant personality scores together demonstrated significant contributions to the prediction of future alcohol problems for demographics in Step 1; demographics and most baseline alcohol items, including response level, in Step 2; and cannabis use in Step 3; after which demographics, LR, baseline alcohol problems, cannabis use, and higher sensation seeking added significantly in Step 4. Regression for each personality domain separately revealed significant contributions to Step 4 for all personality domains except openness. Lower levels of response to alcohol added significantly to all regression analyses.ConclusionsMost tested personality scores and lower levels of response to alcohol contributed to predictions of later alcohol problems even after considering baseline demographic and substance use measures.
Retracted: Maternal traditional Chinese medicine exposure and risk of congenital malformations: a multicenter prospective cohort study
Authors: Peng Ting , Yin Lin‐Liang , Xiong Yu , Xie Feng , Ji Chun‐Ya , Yang Zhong , Pan Qi , Li Ming‐Qing , Deng Xue‐Dong , Dong Jing , Wu Jiang‐Nan 
Published: April 2023

AbstractIntroductionThe potential teratogenic risk of traditional Chinese medicine (TCM) is of widespread concern; however, related evidence is largely absent in humans. This study aimed to compare the prevalence of congenital malformations between pregnant women with and without TCM exposure.Material and methodsThis was a multicenter prospective cohort study of 17 713 women who participated in a survey on periconceptional TCM exposure. Primary outcome was congenital malformations diagnosed from a survey conducted on the day 42 after delivery.ResultsA total of 16 751 pregnant women with 273 congenital malformations were included in the analysis. Fetuses exposed to TCM had an increased risk of congenital malformations compared to those without exposure (odds ratio [OR] 2.10; 95% confidence interval [CI] 1.09–4.02) after controlling for potential confounders. There were significant associations with congenital malformations in women with early pregnant exposure (OR 2.04, 95% CI 1.00–4.20) and for those who received ≥2 TCM formulas (OR 5.84, 95% CI 1.44–23.65). Pre‐pregnancy TCM exposure was significantly associated with an increased risk of congenital heart defects (OR 12.69; 95% CI 3.01–53.51).ConclusionsPericonceptional TCM exposure is associated with an increased risk of congenital malformation. This effect was cumulative and sensitive to periconceptional age. Therefore, TCM deserves more attention and should be used cautiously for pregnant women and those trying to become pregnant.
Socioeconomic differences in parental financial support, coresidence, and advice: A portrait of undergraduate students in the Canadian Prairies
Authors: Mazurik Kathrina , Williamson Linzi , Knudson Sarah 
Published: April 2023

AbstractIn this paper, we examine the intersections of parental support and family socioeconomic background within an undergraduate sample (N= 596) in a mid‐sized Canadian Prairie city. Coresidence, financial support, and parental and professional financial advice are examined as types of ‘family capital’ that may be distributed unequally across socioeconomic groups. In keeping with previous literature, findings showed that students whose parents had university education and higher incomes received more robust coverage of their housing and school expenses. Students whose parents were university‐educated were also more likely to be living with a parent, though no relationship was found between parental income and coresidence. Contrasting with previous literature, few relationships were found between socioeconomic background and receipt or influence of financial advice. These results contribute to the literature by generalising claims about family capital to a Canadian student sample, where relatively few studies have empirically examined intergenerational transfers as mechanisms for transmitting privilege during the transition to adulthood. With increasing demands for higher education and simultaneous declines in government subsidisation of its costs, disparate access to family capital is likely to intensify the reproduction of social inequality across generations.
Protective effects and mechanism of Paecilomyces cicadaeTJJ1213 intracellular polysaccharide against H2O2‐induced PC12 cells damage
Authors: Tian Juanjuan , Xu Qing , Wang Xiaomeng , Zhang Xueliang , Chen Xiaohong , Rui Xin , Zhang Qiuqin , Dong Mingsheng , Li Wei 
Published: April 2023

AbstractOxidative stress is a key process in the development of neurodegenerative diseases. More attention is needed to screen natural antioxidants and explore pharmacological mechanisms. Natural product polysaccharides with no toxic side effects have powerful antioxidant activity. Two purified intracellular polysaccharide fractions (IPS1 and IPS2) from Paecilomyces cicadae TJJ1213 was isolated. Then, a model of H2O2‐induced oxidative stress in PC12 cells was established to investigate the neuroprotective role of IPS and elucidate the potential protection mechanism. Results showed that IPS1 and IPS2 reduced reactive oxygen species (ROS) production, inhibited the leakage of lactate dehydrogenase (LDH) and Ca2+ and attenuated the expression of apoptotic proteins. In addition, western blots displayed that IPS1 and IPS2 significantly inhibited mitophagy induced by H2O2 in PC12 cells via PINK/Parkin pathway. Therefore, IPS1 and IPS2 deserved further investigation as protective agents against neurodegenerative diseases.
The effect of intravenous thrombolysis on patients with successful thrombectomy depends on final reperfusion grade: A retrospective study
Authors: Tang Tao , Li Di , Zhao Man‐Hong , Thomas Aline M. , Chuang Chuang , Fan Tie‐Ping , Li Shen 
Published: April 2023

AbstractAimsAlthough intravenous thrombolysis (IVT) has not shown confirmative effects on the outcomes of patients receiving successful thrombectomy, it might influence the outcomes of a subset of these patients. This study aims to evaluate whether the effects of IVT depend on final reperfusion grade in patients with successful thrombectomy.MethodsThis is a single‐center, retrospective analysis of patients with an acute anterior circulation large‐vessel occlusion and a successful thrombectomy between January 2020 and June 2022. Final reperfusion grade was evaluated by the modified Thrombolysis in Cerebral Infarction (mTICI) score, which was dichotomized into incomplete (mTICI 2b) and complete (mTICI 3) reperfusion. The primary outcome was functional independence (90‐day modified Rankin Scale score 0–2). Safety outcomes were 24‐h symptomatic intracranial hemorrhage and 90‐day all‐cause mortality. Multivariable logistic regression analyses were used to assess the interactions between IVT treatment and final reperfusion grade on outcomes.ResultsWhen comparing all 167 patients enrolled in the study, IVT did not influence the extent of functional independence (adjusted OR: 1.38; 95% CI: 0.65–2.95;p = 0.397). The effect of IVT on functional independence depended on final reperfusion grade (p = 0.016). IVT benefited patients with incomplete reperfusion (adjusted OR: 3.70; 95% CI 1.21–11.30;p = 0.022), but not those with complete reperfusion (adjusted OR: 0.48, 95% CI: 0.14–1.59;p = 0.229). IVT was not associated with 24‐h symptomatic intracerebral hemorrhage (p = 0.190) or 90‐day all‐cause mortality (p = 0.545).ConclusionsThe effect of IVT on functional independence depended on final reperfusion grade in patients with successful thrombectomy. IVT appeared to benefit patients with incomplete reperfusion, but not those with complete reperfusion. Because reperfusion grade cannot be determined prior to endovascular treatment, this study argues against withholding IVT in IVT‐eligible patients.
Safety assessment of a three‐dimensional‐printed autologous omentum patch: An application on the kidneys as a new treatment approach
Authors: Jo Hyunwoo , Kim Janghwan , Kim Jin‐Wook , Kim Boyun , Choi Bo Young , Kang Kyuyong , Ryu Jina , Kim Min Su 
Published: April 2023

AbstractRecently, the field of regenerative medicine has made great strides in the development of new treatments for various organ dysfunctions. One of the most promising new approaches is the use of three‐dimensional (3D) printing and autologous tissues. In this study, we evaluated the safety of a 3D‐printed autologous omentum patch to kidneys using large animals. A total of seven micropigs underwent transplantation of the 3D‐printed autologous omentum patch. Twelve weeks after transplantation, the safety was evaluated by measuring body weight, blood, and the renal resistive index. In addition, biopsy samples were histologically analyzed. The results showed no surgical complications, renal functional hematological changes, or inflammatory responses. Therefore, this study provides important insights into direct therapy to kidneys with a 3D‐printed patch made of autologous tissue. Furthermore, it has the potential for the development of new therapies for various organ dysfunction.
The second phantom aquatic leaf beetle in Japan: Macroplea mutica rediscovery in the wetlands (Coleoptera: Chrysomelidae)
Authors: Nakahama Naoyuki , Okano Ryosuke , Nishimoto Yuichiro , Nakatani Yusuke , Noishiki Asato , Ogawa Naoki 
Published: April 2023

AbstractWetland biodiversity is currently declining on a global scale. Wetland biodiversity understanding is critical for determining the wetlands' conservation value. In this study, Macroplea Samouelle, 1819 (Coleoptera: Chrysomelidae) was discovered in Aomori Prefecture, Honshu Island, Japan. Only two Macroplea species have been recorded in Japan, M. japana (Jacoby, 1885) and M. mutica (Fabricius, 1792). Macroplea japana had been unrecorded for 60 years before being rediscovered in Honshu Island in 2022, and a single adult M. mutica female was discovered in Hokkaido Prefecture in 2003. The discovered individuals were concluded to be M. mutica based on morphological and molecular analyses. Although morphological differences were observed with the Eurasian M. mutica individuals, the male genitalia was nearly identical to M. mutica. For the molecular phylogenetic analysis based on COI and 28S sequences, Macroplea individuals in Japan were clustered with M. mutica on the Eurasian Continent. This is the first record of this species on Honshu Island (and the second in Japan), as well as the first record of adult males. This species would require conservation policies and additional distributional surveys.
Trait evolution during a rapid global weed invasion despite little genetic differentiation
Authors: Irimia Ramona E. , Montesinos Daniel , Chaturvedi Anurag , Sanders Ian , Hierro José L. , Sotes Gastón , Cavieres Lohengrin A. , Eren Özkan , Lortie Christopher J. , French Kristine , Brennan Adrian Christopher 
Published: April 2023

AbstractInvasive species often possess a great capacity to adapt to novel environments in the form of spatial trait variation, as a result of varying selection regimes, genetic drift, or plasticity. We explored the geographic differentiation in several phenotypic traits related to plant growth, reproduction, and defense in the highly invasive Centaurea solstitialis by measuring neutral genetic differentiation (FST), and comparing it with phenotypic differentiation (PST), in a common garden experiment in individuals originating from regions representing the species distribution across five continents. Native plants were more fecund than non‐native plants, but the latter displayed considerably larger seed mass. We found indication of divergent selection for these two reproductive traits but little overall genetic differentiation between native and non‐native ranges. The native versus invasive PST–FST comparisons demonstrated that, in several invasive regions, seed mass had increased proportionally more than the genetic differentiation. Traits displayed different associations with climate variables in different regions. Both capitula numbers and seed mass were associated with winter temperature and precipitation and summer aridity in some regions. Overall, our study suggests that rapid evolution has accompanied invasive success of C. solstitialis and provides new insights into traits and their genetic bases that can contribute to fitness advantages in non‐native populations.
Equine retinal detachment in the United Kingdom: 23 cases (2010–2020)
Authors: Halliwell Elizabeth , Malalana Fernando 
Published: April 2023

SummaryBackgroundFew reports describe the aetiology, presentation and diagnosis of retinal detachment in horses. Equine recurrent uveitis (ERU) and trauma are the most common causes of equine retinal detachment in the United States, but no studies have characterised the disease within the United Kingdom.ObjectivesTo describe clinical presentation, aetiology and diagnostic examination findings of horses with retinal detachment within a UK‐based population.Study designRetrospective case series.MethodsMedical records of horses presented to a single UK referral centre between 2010 and 2020 were reviewed. Horses were diagnosed with retinal detachment by clinical examination and/or ultrasonography, and details of clinical presentation, aetiology and examination findings were recorded.ResultsA total of 23 horses were included. There were 13 geldings and 10 mares with a median age of 9 at presentation (range 4 days to 17 years). Warmbloods were the most common breed (n = 8). Unilateral cases (n = 21) were more common than bilateral (n = 2). ERU was the most common aetiology (n = 10) followed by trauma (n = 8). Three cases presented post‐intraocular surgery, one congenital and one secondary to primary glaucoma. Ultrasound confirmed diagnosis in 23 (100%) cases, but only nine could be visualised by direct ophthalmoscopy. Cataracts, posterior synechiae and vitreal debris were found commonly in both the ipsilateral and contralateral eye affected.Main limitationsSmall sample size. Single‐centre retrospective study which may not be representative of the entire UK population. Histological confirmation of cases was not obtained.ConclusionsCauses of retinal detachment in the studied population are like those previously reported in the USA and most cases presented with complete detachment. Ocular ultrasound is useful in the diagnosis of retinal detachment when the fundus cannot be directly assessed. The presence of retinal detachment should be considered in non‐visual eyes presenting with cataracts, vitreal debris and posterior synechiae.
Navigating health and well‐being during the COVID‐19 pandemic: Experiences of Latina immigrant mothers in rural Midwestern communities
Authors: Williams Ebony , Greder Kimberly , Kim Dahee , Bao Juan , Dan Karami Na‐Omi Hassane 
Published: April 2023

AbstractObjectiveIn this study, we sought to gain insight into the challenges Latina immigrant mothers in rural Midwest communities encountered during the pandemic, strategies they employed to avoid infection of the virus, and impacts of the pandemic on family health and well‐being.BackgroundIn rural Midwestern communities, the pandemic disproportionately affected immigrants, many of whom are Latino and worked in meatpacking and food processing plants. Latina mothers are commonly viewed as caretakers of the family. This prescribed role placed mothers at the center of safeguarding their families' health during the pandemic.MethodIn this descriptive study, we conducted individual interviews with 124 Latina immigrant mothers across six rural Midwestern communities who participated in one of two previous studies in the communities. Thematic analyses was used to identify themes that aligned with three areas of interest: challenges experienced, strategies employed to avoid virus infection, and impacts of the pandemic on family health and well‐being.ResultsMothers enacted behaviors (e.g., sanitation practices, wore masks, stayed home) to lessen negative impacts of the pandemic on family health and well‐being. Factors beyond their control (e.g., public policies, work policies and practices) placed families at greater risk for poor health and well‐being. Eleven themes were identified that aligned with the three areas of interest.ConclusionFindings build upon and extend prior research that reexposed unjust employment conditions, inadequate health‐care systems, and an anti‐immigrant context during the pandemic that perpetuated health disparities among Latino immigrants and other minoritized populations.ImplicationsEthnographic and longitudinal studies that give voice to populations underrepresented in COVID‐19 research and at high risk for poor health are warranted to inform policies and practices to protect health during public health crises.
Characterization of ferredoxins from the thermophilic, acetogenic bacterium Thermoanaerobacter kivui
Authors: Katsyv Alexander , Essig Melanie , Bedendi Giada , Sahin Selmihan , Milton Ross D. , Müller Volker 
Published: April 2023

A major electron carrier involved in energy and carbon metabolism in the acetogenic model organism Thermoanaerobacter kivui is ferredoxin, an iron–sulfur‐containing, electron‐transferring protein. Here, we show that the genome of T. kivui encodes four putative ferredoxin‐like proteins (TKV_c09620, TKV_c16450, TKV_c10420 and TKV_c19530). All four genes were cloned, a His‐tag encoding sequence was added and the proteins were produced from a plasmid in T. kivui. The purified proteins had an absorption peak at 430 nm typical for ferredoxins. The determined iron–sulfur content is consistent with the presence of two predicted [4Fe4S] clusters in TKV_c09620 and TKV_c19530 or one predicted [4Fe4S] cluster in TKV_c16450 and TKV_c10420 respectively. The reduction potential (Em) for TKV_c09620, TKV_c16450, TKV_c10420 and TKV_c19530 was determined to be −386 ± 4 mV, −386 ± 2 mV, −559 ± 10 mV and −557 ± 3 mV, respectively. TKV_c09620 and TKV_c16450 served as electron carriers for different oxidoreductases from T. kivui. Deletion of the ferredoxin genes led to only a slight reduction of growth on pyruvate or autotrophically on H2 + CO2. Transcriptional analysis revealed that TKV_c09620 was upregulated in a ΔTKV_c16450 mutant and vice versa TKV_c16450 in a ΔTKV_c09620 mutant, indicating that TKV_c09620 and TKV_c16450 can replace each other. In sum, our data are consistent with the hypothesis that TKV_c09620 and TKV_c16450 are ferredoxins involved in autotrophic and heterotrophic metabolism of T. kivui.
Impacts of sensory multimodality congruence and familiarity with short use on cosmetic product evaluation
Authors: Bourdier Alice , Abriat Anne , Jiang Tao 
Published: April 2023

AbstractCross‐modal association between sensory modalities is a natural phenomenon in the perception of our environment. For cosmetic evaluation, touch and smell are the two major sensory modalities involved in the whole product perception. In this study, we investigate whether a specific cosmetic texture is preferentially associated with a specific fragrance: congruence between texture and fragrance. In addition, we investigate whether 1‐week use of a fragrance–texture congruent or non‐congruent product can influence user's whole product appreciation and well‐being. We have conducted a four‐test experiment with 29 participants; first in the laboratory to evaluate: six fragrances and four textures individually with free description (test 1); the same stimuli with a description with cross‐modal descriptors (test 2); 10 fragrance–texture combined products (test 3); and secondly at home, two fragrance–texture combined products: one congruent and one non‐congruent (test 4). Results showed that: (1) For a given texture type, specific olfactory notes are necessary to lead to a congruent cross‐modal pairing product. (2) Sensory modal congruent products produce the highest hedonic response. (3) Real‐life use or familiarisation with a product can influence not only the degree of cross‐modal congruence but also overall cosmetic product appreciation.
Effect of thermal exposure on the microstructure and strength of an alumina‐silica ceramic fiber
Authors: Yang Rui , Zhao Wenqing , Sun Shijie , Yang Jinhua , Jiao Jian 
Published: April 2023

AbstractThe microstructure and mechanical properties of an alumina‐silica ceramic fiber after thermal exposure at 1100–1300°C were investigated by X‐ray diffraction, nuclear magnetic resonance, scanning electron microscopy, transmission electron microscopy analyses and room temperature tensile strength test. The results showed that the fiber was composed of γ‐A12O3 and amorphous SiO2. A phase reaction of γ‐A12O3 and amorphous SiO2 occurred when thermal exposure temperature exceeded 1150°C, and a new mullite phase formed. The grain size of the newly formed mullite increased with the increase of exposure temperature. Both the phase transition and grain growth of mullite had a significant impact on the mechanical properties of the fiber. Tensile strength of the fiber decreased slightly when thermal exposure temperature was below 1150°C, while the strength retention of the fiber decreased sharply to 65.36% as exposure temperature rose to 1200°C. A higher dispersion of tensile strength was also observed at higher exposure temperatures, as revealed by the Weibull statistical model.