bluuebunny/crossref_metadata_2025_split huggingface dataset:
Etomidat Menurunkan Kadar Gula Darah Pasca Induksi Anestesi
Authors: Riffayadi Oddi , Jatmiko Heru Dwi , Sasongko Himawan 
Published: December 2022

Latar belakang: Kekhawatiran etomidat menyebabkan hipoglikemi menjadi masalah. Onset aksi cepat, profil kardiovaskuler rendah dan kurang signifikan menyebabkan penurunan tekanan darah membuat etomidat menjadi pilihan obat anestesi induksi yang cukup baik.Tujuan: membuktikan pengaruh pemberian etomidat dalam menyebabkan penurunan kadar gula darah. Metode: merupakan penelitian pretest postest controlled design pada 40 pasien yang menjalani operasi dengan anestesi umum, dibagi menjadi dua kelompok (n=20), kelompok1,etomidat 0,2 mg/kg ( E2) dan kelompok 2, 0, 4 mg/ kg ( E4). Masing- masing kelompok diperiksa kadar gula darah sebelum 2 jam dan 6 jam sesudah induksi. Uji statistik pair T-test dan Wilcoxon rank sum test terhadap E2 dan E4. Hasil: pada E2 terdapat perbedaan bermakna P= 0,05 antara sebelum dan 2 jam sesudah perlakuan 106, 95 ± 15, 453 mg/dl – 96, 40 ± 14, 966 mg/ dl ; 2 jam dan 6 jam sesudah perlakuan P= 0, 016 ; 96, 40 ±14, 966 mg/dl – 108, 85 ± 27, 238 mg/dl. Sedangkan pada E4 terdapat perbedaan bermakna P= 0, 041 baik sebelum dan 2 jam sesudah 102,60n± `12, 696 mg/dl – 99, 35 ± 15, 938 mg/dl ; sebelum dan 6 jam sesudah perlakuan P= 0, 041; 99, 35 ± 15, 938 mg/dl – 98, 25 ±± 19, 878 mg/dl. Tetapi tidak terdapat perbedaan bermakna antara E2 dan E4 dalam menyebabkan penurunan kadar gula darah baik 2 jam P= 0, 550 ; 96, 40 ± 14, 966 mg/ dl- 99, 35 ± 15, 938 mg/ dl, maupun sesudah 6 jam pemberian P= 0, 104 ; 108, 85 ± 27, 238 mg/ dl – 98, 25 ± 19, 878 mg/dl. Secara statistik etomidat menurunkan kadar gula darah baik pada E2 maupun pada E4 tetapi masih dalam batas normal atau secara klinik tidak bermakna. Kesimpulan: etomidat 0, 2 mg/dl (E2) dan 0, 2 mg/ dl (E4) secara statistik bermakna menurunkan kadar gula darah pada 2 jam dan 6 jam sesudah induksi
Ketamin dan Meperidin Untuk Pencegahan Menggigil Pasca Anestesi Umum
Authors: Sarim Budi Yulianto , Budiono Uripno , Sutiyono Doso 
Published: December 2022

Latar Belakang: Menggigil pasca anestesi merupakan komplikasi yang cukup sering terjadi. Menggigil menimbulkan keadaan yang tidak nyaman dan berbagai resiko. Karena itu menggigil harus segera dicegah atau diatasi. Sampai saat ini obat paling sering digunakan adalah meperidin. Tujuan: Membuktikan bahwa pemberian ketamin 0,25 mg/kgBB intra vena menjelang akhir operasi lebih efektif dari pada meperidin 0,5mg/kgBB intra vena menjelang akhir operasi untuk mencegah kejadian menggigil pasca anestesi umum. Metode: Merupakan penelitian eksperimental dengan desain “randomized post test only controlled group” pada 72 pasien dengan usia 16 – 60 tahun yang menjalani operasi dengan anestesia umum. Tanda vital ( Tekanan darah diastolik dan sistolik, tekanan arteri rerata, laju jantung dan SaO2 ) diukur 5 menit sebelum induksi. Prosedur induksi anestesi umum dilakukan sesuai standar. Temperatur esofagus diukur segera setelah induksi. Lama operasi dibatasi antara 2 -3 jam. Pada akhir operasi, obat inhalasi dihentikan. Setelah nafas spontan adekuat, reflek laringeal positif dilakukan randomisasi. Pasien dibagi menjadi tiga kelompok, dan mendapatkan secara intravena ketamin 0,25 mg/kgBB untuk kelompok 1, meperidin 0,5 mg/kgBB untuk kelompok 2 dan NaCI 0,9% untuk kelompok 3. Ekstubasi dilakukan 5 menit setelah perlakuan. Tanda vital di ukur dicatat segera setelah ekstubasi dan tiap lima menit selama 30 menit. Suhu tubuh diukur segera dan 15 menit setelah ekstubasi. Pasca ekstubasi pasien diberi oksigen 6L/menit. Uji statistik dilakukan dengan menggunakan One-way ANOVA dan Chi- kuadrat, dengan derajat kemaknaan yaitu p<0,005. Hasil: Data dasar dan data karakteristik klinis sebelum induksi, berbeda tidak bermakna (p>0,05). Terdapat perbedaan bermakna tanda vital antara kelompok 1 dengan kelompok 3 saat setelah ekstubasi. Kejadian menggigil pada grup 1 yaitu 4 orang (16,6%) terdiri dari 3 orang menderita derajat 1 dan 1 orang menderita derajat 2, sedangkan pada kelompok 2 terjadi pada 5 orang (20,8%) terdiri dari 4 orang derajat 1 dan 1 orang derajat 2, hal ini secara statistik berbeda tidak bermakna (p=0,500). Perbedaan suhu tubuh grup 1 dan grup 2 berbeda tidak bermakna (p>0,05). Efek samping obat yang timbul pada kelompok 1 sebanyak 1 penderita mengalami mual, sedangkan kelompok 2 sebanyak 7 penderita mengalami mual dan 2 penderita depresi nafas, berbeda bermakna (p=0,012). Kesimpulan: Ketamin 0,25 mg/kgBB dan meperidin 0,5 mg/kgBB mempunyai efektifitas yang sama dalam mencegah menggigil pasca anestesi umum, tetapi ketamin mempunyai efek samping mual yang lebih rendah dibandingkan meperidin.
Sprawozdanie z XXVI Zjazdu Katedr, Zakładów i Zespołów Badawczych Prawa i Postępowania Administracyjnego pt. „Kierunki rozwoju jurysdykcji administracyjnej”, Poznań, 18-20 września 2022 r.
Authors: Krzanowski Marcel 
Published: December 2022

Sprawozdanie z XXVI Zjazdu Katedr, Zakładów i Zespołów Badawczych Prawa i Postępowania Administracyjnego pt. „Kierunki rozwoju jurysdykcji administracyjnej”, Poznań, 18-20 września 2022 r.
Marcel Krzanowski
Opiniowanie miejscowych planów zagospodarowania przestrzennego przez wojewódzkich inspektorów ochrony środowiska w związku z lokalizacją zakładów zagrożonych poważną awarią
Authors: Bukowski Zbigniew 
Published: December 2022

The article deals with the issuing of opinions on local spatial development plans by the voivodeship environmental protection inspector in connection with the location of plants at risk of a serious accident. The article analyses in detail the regulations in the aforementioned ﬁeld. The following conclusions were adopted:1. Not in every case is the local spatial development plan referred to the voivode-ship environmental protection inspector for an opinion;2. after the commune council adopts a resolution to begin drawing up the local plan, it is the commune head, mayor or city president that decides to apply to the voivodeship environmental protection inspector for an opinion on the draft plan, provided that the plan allows the location of plants posing a risk of a serious in-dustrial accident;3. should the head of the commune, mayor or president not request that the voivodship environmental protection inspector issue an opinion on the draft plan, this will constitute a violation of the plan preparation procedure if the plan allows the location of plants posing the risk of a serious industrial accident;4. issues related to the deadline for giving an opinion and its extension are regu-lated in the Act on Spatial planning and development, which regulations constitute a lex specialis to the Code of Administrative Procedure;5. any failure by the commune head, mayor, city president to take into account the negative opinion of the voivodeship environmental protection inspector, based on speciﬁc regulations concerning the location of plants posing the risk of a serious industrial accident, is a violation of the law.
How Motivated are Teachers to Promote Self-Regulated Learning? A Latent Profile Analysis in the Context of Expectancy-Value Theory
Authors: Hirt Carmen Nadja , Jud Johannes , Rosenthal Amina , Karlen Yves 
Published: December 2022

Motivation is a core element of teachers’ professional competences and, therefore, of great importance to teaching and learning. Motivation might explain why teachers do or do not promote self-regulated learning (SRL). Drawing on expectancy-value theory (EVT), this study used a person-centred approach to investigate to what extent multiple motivational aspects (self-efficacy; intrinsic interest, extrinsic utility, and attainment value; opportunity and effort costs) shape teachers’ motivational profiles. It examined the extent to which those profiles differ regarding experience in promoting SRL, the implicit theory of SRL, and the promotion of SRL. The study sample consisted of N = 280 in-service teachers (51.8% women; Mage = 44.34, SD = 10.82). Three profiles were identified: The high costs profile (profile 1, 30.8% of teachers), the moderate profile (profile 2, 24.4% of teachers), and the high success expectations and task values profile (profile 3, 44.8% of teachers). Further analyses revealed significant differences between these profiles concerning experience in promoting SRL, implicit theory of SRL, and the promotion of SRL, with Profile 1 showing the lowest values and Profile 3 the highest for each factor. The study found that high expectations are associated with high values, and costs are low when expectations and values are high and vice versa. This is in line with the assumptions of EVT and is applicable to all three profiles. These results indicate a clear need to support teachers in promoting SRL, especially those with high perceived costs, to ensure costs do not override the other considerations in EVT. Overall, this study is ‘frontline’ because it highlights the relevance of motivation as an aspect of teachers’ professional competences in promoting SRL. Furthermore, this study emphasizes the importance of combining EVT and SRL to provide a more nuanced picture of teachers’ motivation to promote SRL. It offers new insights that could influence the conceptualization of professional development programs for SRL.
Principles of ideal diagnostic regulation and the IVDR
Authors: Hallersten Anna Margareta , Decker Nicholas Michael , Huang Yasha 
Published: December 2022

Abstract
This article discusses principles and concepts for ideal regulatory frameworks for diagnostics, and the expression of those principles in the EU IVDR. The authors present the benefits of regulatory frameworks and implementation approaches for diagnostics that are risk-based, globally convergent, connected, nimble and efficient, under the IVDR and with a future outlook. While many expressions of these principles can already be found in the EU IVDR text, and in its implementation approaches, their further embrace is needed in future EU diagnostic regulation. In the long term outlook, risk-based approaches can be extended to comprise entity-based excellence appraisals. Globally convergent approaches can be more explicit in e.g. qualification and classification of products. This will also help further reliance models. Better connections and cooperation between regulators across the healthcare spectrum including pharmaceuticals should be fostered. Nimble approaches such as Emergency Use Authorisations for pandemics are essential in highly regulated schemes like the IVDR and beyond. Finally, regulatory efficiency as in timely availability of IT infrastructure and oversight mechanisms is a distinguishing attribute of globally competitive diagnostic regulatory schemes. All the above needs consideration in the long term efforts to modernize the EU regulatory system, so that diagnostics can play their important role in clinical research as well as along the entire care continuum in the EU.
Ethical tension in nursing education: a challenge for faculty values and beliefs
Authors: Baumberger-Henry Mary , Kucirka Brenda 
Published: December 2022

AbstractObjectivesThe culture of the academic setting can be fraught with tension filled ethical situations challenging faculty relations with students and colleagues. Therefore, the purpose of this qualitative study was to identify the process that occurs when nursing faculty encounter tension filled situations affecting their ethical values and beliefs in the education setting.MethodsA grounded theory approach was employed to achieve data saturation from interviews of thirteen faculty representing eight colleges/universities in three states of the MidAtlantic region of the United States.ResultsThe Basic Social Psychological Process that emerged from the data demonstrated faculty efforts toward safeguarding profession, student, and self. Three concepts: experiencing, identifying, and resolving evolved.ConclusionsData evidenced that ethical tension negatively influences one’s work-life balance, and civility with faculty and students. Implications for balancing these influences and working toward a harmonious environment are provided.
Critique of Lithic Reason
Authors: Di Maida Gianpiero 
Published: December 2022

Abstract
In this article, the author would like to raise the attention on some structural problems at the bottom of past and present approaches within lithic studies, specifically the classificatory enterprises, thus contributing to the theoretical discussions around it. As a stepping stone towards the future resolution of these issues embedded in the current typological classification methods and in the technological approach, a proposal is made that from one side suggests uniforming and regularising the formal representation of lithic analyses in a more systematic and less erratic way and from the other side praises a more inclusive approach and better integration of typological analysis within current lithic studies.
Reexamining Ceramic Standardization During Agricultural Transition: A Geometric Morphometric Investigation of Initial – Early Yayoi Earthenware, Japan
Authors: Loftus James Frances 
Published: December 2022

Abstract
The quantifiable and reproducible representation of variability in material culture has continued to play a key role in the elucidation of shifting patterns of production organization in prehistoric archaeology. The study of standardization of ceramics has traditionally illuminated on how agents shift means of production to a common goal. However, while geometric morphometric (GMM) approaches to standardization quantification overcome issues of reproducibility faced in traditional literature, the lack of widespread radiocarbon dating in Japan requires adherence to traditional methods of temporal control. This study seeks to extrapolate ceramic standardization in a quantifiable means, while also maintaining temporal control utilizing traditional methods. In a pilot case study of the agricultural transition period of the Yayoi period of the Japanese peninsula (∼900/800 BC–300 BC), results of mortuary vessels show that while a previous model based on visually determined traditional methods assumed that ceramic manufacture was centralized in the Hakata Bay subregion of the northern Kyushu island region; utilizing GMM analysis to extrapolate variable standardization is able to identify a decline in morphological variation, despite increases in population density and potential variability between migrant and indigenous production patterns. These results further illuminate the strong correlation between production intensity and its effect on standardization practices in material culture production, as seen in modern ethnoarchaeological literature.
Tailoring 2D carbides and nitrides based photo-catalytic nanomaterials for energy production and storage: a review
Authors: Riaz Asma , Tahir Muhammad Bilal , ur Rehman Jalil , Sagir Muhammad , Yousef El Sayed , Alrobei Hussein , Alzaid Meshal 
Published: December 2022

Abstract
2D carbides and nitrides-based nanomaterials because of their unusual physical and chemical properties and a vast range of energy-storage applications have attracted tremendous attention. However, 2D carbides and nitrides-based nanomaterials and their corresponding composites have many intrinsic constraints in terms of energy-storage applications. The nano-engineering of these 2D materials is widely investigated, to improve their performance for practical application. In this Review article, the current progress and research on 2D carbides and nitrides-based nanostructures are presented and debated, concentrating on their methods of preparation, and energy conservation applications for example Lithium-ion-battery, supercapacitors, and Sodium-ion-battery. In conclusion, the problems, and recommendations essential to be discussed for the progress of these 2D nanomaterials for energy-storage applications based on carbides and nitrides are displayed.
Life of a Colombian Musician: Music Autobiography, Cosmopolitan Musickings, and Agonistic Objectification
Authors: Pantoja Daniel F. Castro 
Published: December 2022

Abstract
This article presents an analytical framework for the study of Latin American music autobiographies. I take Colombian composer Guillermo Uribe Holguín’s 1941 autobiography Vida de un músico colombiano as a paradigmatic case in order to argue that Latin American music autobiographies are not secondary sources that lack historical or literary value—a common historiographical assumption—but rather agonistic and intermedial objects that intervene in local and translocal networks. In addition to introducing recent literature on music autobiographies, the article expands on post-foundationalist political thought to make a case for a renewed examination of Latin American music autobiographies and their relevance to the study of music, sound, and the political. In my reading of the Vida, I consider Uribe Holguín’s literary inscription of cosmopolitan musickings, anxieties, and agentic claims and evaluate their potential to at once reify and/or disarticulate a nationalist-populist poetics, the conflation of partisan struggle with national identity, and narratives of European and Euro-American exceptionalism in global music histories. The article also discusses how other political actors continue to use the Vida to sound and perform a politics of belonging in contraposition to Uribe Holguín’s non-national, cosmopolitan autobiographical self. The last section exposes Michael Herzfeld’s notion of cultural intimacy to Ernesto Laclau and Chantal Mouffe’s category of antagonism to account for the Vida’s reception beyond national borders and analyze the performances of cosmopolitan subjectivity it enabled among actors at the margins of a global modernity who saw themselves as precarized by the geopolitics of Western art music.
CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium
Authors: Prieto Susana , Dubra Geronimo , Camasses Alain , Aznar Ana Bella , Begon‐Pescia Christina , Simboeck Elisabeth , Pirot Nelly , Gerbe François , Angevin Lucie , Jay Philippe , Krasinska Liliana , Fisher Daniel 
Published: December 2022

AbstractCDK8 and CDK19 form a conserved cyclin‐dependent kinase subfamily that interacts with the essential transcription complex, Mediator, and also phosphorylates the C‐terminal domain of RNA polymerase II. Cells lacking either CDK8 or CDK19 are viable and have limited transcriptional alterations, but whether the two kinases redundantly control cell proliferation and differentiation is unknown. Here, we find in mice that CDK8 is dispensable for regulation of gene expression, normal intestinal homeostasis, and efficient tumourigenesis, and is largely redundant with CDK19 in the control of gene expression. Their combined deletion in intestinal organoids reduces long‐term proliferative capacity but is not lethal and allows differentiation. However, double‐mutant organoids show mucus accumulation and increased secretion by goblet cells, as well as downregulation of expression of the cystic fibrosis transmembrane conductance regulator (CFTR) and functionality of the CFTR pathway. Pharmacological inhibition of CDK8/19 kinase activity in organoids and in mice recapitulates several of these phenotypes. Thus, the Mediator kinases are not essential for cell proliferation and differentiation in an adult tissue, but they cooperate to regulate specific transcriptional programmes.
Territorial Structure of Municipal Government at the Present Stage
Authors: Zabelina E. P. 
Published: December 2022

The paper analyzes federal constitutional laws concerning the entry into the Russian Federation of its new constituent entities — Donetsk and Lugansk People’s Republics, Zaporozhye and Kherson regions — in terms of regulating territorial organization of local self-government. The author analyzes upcoming transformations, makes and justifies proposals regarding the need to expand the system of municipalities in new constituent entitties of the Russian Federation by including settlements as its local self-government territories. The implementation of such a provision will comply with Federal Law No. 131-FZ dated 06.10.2003 «On General Principles of Organization of Local Self-Government in the Russian Federation» and will allow the population of rural and other settlements to participate more actively in local self-government.The paper describes the principles of the territorial basis of local self-government and clarifies the possibilities of their preservation in the conditions of the ongoing transformations of local self-government, due to the introduction of amendments to the Constitution of the Russian Federation in 2020. The author characterizes the procedures fixed in the legislation for ensuring changes in the boundaries of municipalities, transformation and abolition of municipalities, analyzes the norms of relevant laws of constituent entitties of the Russian Federation and municipal legal acts specifying the procedure for solving territorial issues of local self-government, illustrates the process of consolidation of municipalities on the example of the Moscow region. It is noted that in the Russian Federation there is a three-level legal regulation of the municipal-territorial structure, including federal and regional legislation and municipal legal acts. This makes it possible to determine substantive powers of public authorities in this area of local self-government and establish the procedure for their enforcement. Taking into account the results obtained, draft Federal Law No. 40361-8 «On general principles of organization of local self-government in the unified system of public authority» is analyzed in order to identify the degree of stability of the existing system of territorial organization of local self-government. The author summarizes that adoption of the enactment under consideration will not entail significant changes, its principles and will not change the procedure for resolving issues of territorial organization of municipal power.
PEMETAAN ASAL SEKOLAH, PRESTASI AKADEMIK DAN NON AKADEMIK DALAM UPAYA MENINGKATKAN KUALITAS INPUT MAHASISWA FAKULTAS ILMU AGAMA ISLAM UNIVERSITAS ISLAM INDONESIA
Authors: Yuli Astuti Mia , Pradima Sari Ikke , Anfani Fahmi Rizki 
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pemetaan asal sekolah terhadap prestasi akademik maupun non-akademik mahasiswa Fakultas Ilmu Agama Islam Universitas Islam Indonesia yang akan dijadikan acuan sebagai strategi pemasaran Fakultas Ilmu Agama Islam Universitas Islam Indonesia guna meningkatkan kualitas input mahasiswa ke depannya. Survei ini didasarkan pada penyebaran kuesioner dengan teknik cluster random sampling kepada mahasiswa di tiap program studi Fakultas Ilmu Agama Islam Universitas Islam Indonesia. Hasil penelitian menunjukkan bahwa mayoritas latar belakang mahasiswa Fakultas Ilmu Agama Islam berasal dari sekolah yang berbasis Islam, selaras dengan mahasiswa berprestasi yang juga didominasi oleh sekolah Islam berbasis pesantren. Prestasi yang ditorehkan mahasiswa dari sekolah Islam berbasis pesantren tidak sebatas pada kategori keislaman, namun juga pada kategori umum. Sedangkan daerah asal mahasiswa berprestasi didominasi oleh Jawa Tengah dan Jawa Timur serta di luar Jawa didominasi oleh Lampung dan Sumatera Utara. Maka, pemasaran FIAI UII direkomendasikan lebih difokuskan pada sekolah Islam berbasis pesantren di daerah Jawa Tengah, Jawa Timur dan Jawa Barat.