bluuebunny/crossref_metadata_2025_split huggingface dataset:
Congenital hepatoblastoma presenting with hepatic arteriovenous fistulas: a case report
Authors: Lin Jiao , Guo Jialing , Chen Chun , Jiang Liqiong , Lai Can , Wang Chunlin 
Published: July 2023

AimCongenital hepatoblastoma, a rare malignant liver tumor in infancy, typically presents with abdominal distension or mass. Tumors detected antenatally or during the first three months of age are considered congenital hepatoblastoma. Hepatic arteriovenous fistulas (HAVF) are associated with high mortality in the neonatal period and can be caused by many secondary factors. This case report focuses on a patient with congenital hepatoblastoma accompanied by HAVF, highlighting the clinical and imaging characteristics and management strategies.Case presentationA term infant presented with sudden tachypnea and heart failure on his first day of life. A cystic-solid mixed lesion in the fetus’s liver was detected by an antenatal ultrasound scan. Postnatal digital subtraction angiography confirmed the presence of arteriovenous fistulas, which were treated with trans-arterial embolization. However, despite the intervention, the patient’s heart failure did not improve. The patient underwent a left hepatectomy, and hepatoblastoma was discovered by histology of the resected hepatic lobe. Unfortunately, metastases were later discovered in the intracranial and ocular regions. Ultimately, the family decided to discontinue further treatment.ConclusionCongenital hepatoblastoma presenting with hepatic arteriovenous fistulas has not been previously described. Hepatoblastoma should be considered when alpha-fetoprotein levels show a significant elevation in newborns. Prenatal diagnosis may improve pre- and postnatal management.
Renal mitochondrial restoration by gymnemic acid in gentamicin-mediated experimental nephrotoxicity: evidence from serum, kidney and histopathological alterations
Authors: Gumbar Shubhangi , Bhardwaj Sudeep , Mehan Sidharth , Khan Zuber , Narula Acharan S. , Kalfin Reni , Tabrez Shams , Zughaibi Torki A. , Wasi Samina 
Published: July 2023

Background: Nephrotoxicity refers to the toxigenic impact of compounds and medications on kidney function. There are a variety of drug formulations, and some medicines that may affect renal function in multiple ways via nephrotoxins production. Nephrotoxins are substances that are harmful to the kidneys.Purpose: This investigation examines the renoprotective effect of gymnemic acid (GA) on Wistar rats in gentamicin-induced nephrotoxicity by analyzing serum, kidney, and histopathological markers.Study-design/methods: The current study investigated the protective effect of GA at doses of 20, 40, and 60 mg/kg against gentamicin-induced nephrotoxicity in rats. Vitamin E was administered to compare the antioxidant capacity and efficacy of GA. In addition to the treatment groups, 100 mg/kg of gentamicin was administered intraperitoneal for 14 days. At the end of the study protocol, kidney homogenate, blood, and serum were evaluated biochemically. Serum creatinine, blood urea, glomerular filtration rate (GFR), mitochondrial dysfunctions, inflammatory cytokines, and renal oxidative stress were examined to assess gentamicin-induced nephrotoxicity. In addition, the impact of GA on the above-mentioned nephrotoxic markers were evaluated and further confirmed by histological analysis.Results: This study establishes a correlation between antibiotic use, especifically aminoglycosides and acute renal failure. The research demonstrates the nephrotoxic effects of aminoglycosides, inducing mitochondrial ETC-complex dysfunction, and renal tissue inflammation in experimental rats. GA’s antioxidant properties restored renal oxidative stress markers, reducing kidney inflammation and injury. Histopathological analysis revealed a significant reduction in renal injury with GA treatment. Additionally, GA demonstrated greater efficacy than Vitamin E in restoring antioxidant potential and mitochondrial enzymes.Conclusion: Consequently, our findings imply that long-term use of GA may be a suitable therapeutic strategy for reducing aminoglycoside toxicity. The current study suggests GA’s potential in treating gentamicin-induced nephrotoxicity and acute renal failure, meriting further investigation using advanced techniques.
Accurate segmentation of infrared images for circuit board diagnosis using an improved Deeplabv3+ network
Authors: Hao Jianxin , Xia Xuan , Wang Li , Li Zhixin , Zhu Meng 
Published: July 2023

An effective infrared image segmentation algorithm is essential for non-contact fault diagnosis of circuit boards. However, the uneven grayscale of the infrared images, multiple target regions, and large radiation noise pose challenges to achieving accurate segmentation and efficient data extraction for the interested regions. In this paper, we propose a segmentation algorithm based on the Deeplabv3+ network, using the lightweight MobileNetV2 as a replacement for the original Xception backbone network to improve computational efficiency and reduce overfitting. We also employ a composite loss function and cosine annealing learning rate to balance foreground-background segmentation and avoid local optima. Furthermore, we integrate the Convolutional Block Attention Module (CBAM) to extract and combine important spatial and channel features, allowing the algorithm to focus on identifying elements of the circuit board instead of background pixels, thereby improving segmentation accuracy. Experimental results demonstrate that our proposed algorithm achieves state-of-the-art performance in terms of both segmentation accuracy and computational efficiency on our self-built infrared circuit board dataset, with a MIoU of 90.34%, MPA of 95.26%, and processing speed of 25.19 fps. Overall, our proposed segmentation algorithm can effectively identify the key regions of interest in infrared images of circuit boards, providing technical support for non-contact diagnosis.
Bayesian optimization for design of high-repetition-rate laser-driven muon source
Authors: Sha Rong , Wang Bing-Lin , Zhao Jie , Duan Xiao-Jun , Yan Liang , Xia Guo-Xing , Yu Tong-Pu 
Published: July 2023

With the increasing repetition rate of ultra-intense laser pulses, ion beams accelerated by these lasers show great potential for achieving high-repetition-rate, high-average-flux muon sources. Nonetheless, generating high-quality ion beams is a challenging feat as it demands a careful balance among numerous physical effects. In this study, we utilize Bayesian optimization to fine-tune laser and plasma parameters to produce high-charge energetic ion beams, consequently leading to a high-yield muon source via pitcher-catcher scheme. Beginning with initial points steered by Latin hypercube sampling, Bayesian optimization conducts an adaptive, multi-parameter exploration of input parameter space, significantly faster than univariate uniform scans, and results in a mm-scale ps-duration laser-ion-based muon source scheme providing 106π± and 104μ+ at a 10 Hz frequency, using only several tens of simulations.
Weed infestation and productivity of wheat crop sown in various cropping systems under conventional and conservation tillage
Authors: Minhas Waqas Ahmed , Mumtaz Naima , Ur-Rehman Hafeez , Farooq Shahid , Farooq Muhammad , Ali Hayssam M. , Hussain Mubshar 
Published: July 2023

IntroductionClimate change, pest infestation, and soil degradation are significantly reducing wheat (Triticum aestivum L.) yield. Wheat is cultivated in rice-wheat and cotton-wheat cropping systems and escalating global population is exerting substantial pressure on the efficiency of these systems. Conservation tillage and crop rotation could help in lowering soil degradation and pest infestation, and improving wheat yield.MethodsThis three-year study evaluated soil properties, weed infestation and wheat yield under various tillage and cropping systems. Six different cropping systems, i.e., cotton-wheat, sorghum-wheat, mungbean-wheat, rice-wheat, sunflower-wheat, and fallow-wheat (control) and three tillage systems, i.e., conventional tillage (CT), zero-tillage (ZT) and minimum tillage (MT) were included in the study.ResultsThe individual and interactive effects of tillage and cropping systems significantly affected soil properties, weed infestation and yield of wheat crop. Overall, CT resulted in lower soil bulk density and higher porosity, while ZT behaved oppositely at all locations in this regard. Similarly, mungbean-wheat cropping system resulted in lower bulk density and higher porosity and nitrogen (N) contents, while fallow-wheat cropping system resulted in higher bulk density, and lower soil porosity and N contents. Similarly, ZT and CT resulted in higher and lower weed infestation, respectively. Likewise, lower and higher weed density and biomass were recorded in wheat-sorghum and wheat-fallow cropping systems, respectively at all locations. In the same way higher number of productive tillers, number of grains per spike, 1000-grain weight, grain yield, and economic returns of wheat crop were recorded for CT, whereas ZT resulted in lower values of these traits. Regarding interactions, wheat-mungbean cropping system with CT resulted in lower bulk density and higher porosity and N contents, whereas wheat-fallow system with ZT behaved oppositely at all locations in this regard. Similarly, higher and lower values for yield-related traits and economic returns of wheat crop were noted for mungbean-wheat cropping system under CT and fallow-wheat and sorghum-wheat cropping systems under ZT, respectively. It is concluded that the mungbean-wheat cropping system improved wheat productivity and soil health and sorghum-wheat cropping system could lower weed infestation. Therefore, these cropping systems can be practiced to lower weed infestation and improve wheat yield and economic returns.
Effects of emotionally oriented parental interventions: a systematic review and meta-analysis
Authors: Zahl-Olsen Rune , Severinsen Linda , Stiegler Jan Reidar , Fernee Carina Ribe , Simhan Indra , Rekdal Sondre Sverd , Bertelsen Thomas Bjerregaard 
Published: July 2023

ObjectiveThis systematic review and meta-analysis investigates the effects of emotionally oriented parental interventions.BackgroundSeveral emotionally oriented parental interventions have been developed during the last decade. Some of these have gained popularity and spread across several continents. The literature is growing and consists of qualitative studies; intervention only, quasi-experimental, case-control studies; and randomized controlled trials. They indicate effects for parents and children. However, no systematic review or meta-analysis has, to our knowledge, summarized the results.MethodUsing several search engines, we located 8,272 studies. After abstract and full-text screening, 33 studies were assessed for bias and included in the study. Outcomes for parents and children were extracted and combined into three constructs for parents and two for children. Meta-analyses were conducted for each construct to estimate the effect of the interventions using a robust Bayes meta-analysis.ResultsThe results indicate the presence of a small to medium effect on parents' mental health, behavior, and use of emotionally oriented parenting, as well as on children's internalizing and externalizing difficulties. Most participants were recruited from the general population, and clinical settings were rare. The results show little evidence of publication bias.ConclusionThere is evidence of a small to medium effect of emotionally oriented interventions on parents and children.Systematic review registrationhttps://osf.io/un3q4/.
Efficacy of interpersonal psychotherapy in mainland China: a systematic review and meta-analysis
Authors: Tang Luhan , Xu Fangzhong , Yu Ge , Li Chong , Wen Sijin , Zheng Wanhong 
Published: July 2023

ObjectiveInterpersonal Psychotherapy (IPT) is an evidence-based therapy. There have been increasing demand and training opportunities of IPT in China. Reviewing current evidence on its use in Chinese patients can help us understand the applicability of IPT in China and identify knowledge gaps to encourage and better future research in this field.MethodWe did a comprehensive search of three major electronic databases: PubMed (English), Chinese National Knowledge Infrastructure (CNKI) and WanFang Data (Chinese). We examined overall study design, outcome measures, data analyses and other parameters. We only selected articles of Randomized Clinical Trials (RCT) for this review. All study findings were grouped and summarized per psychiatric diagnoses. The meta-analysis and forest plots were performed whereas studies could be combined.ResultsAfter a full text review of 132 articles, 40 were selected for the final review. Comparing with control groups, evidences supported the efficacy of IPT in Chinese patients with Major Depressive Disorder (MDD), Postpartum depression, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder, Post Stress Traumatic Disorder (PTSD), and Post-psychotic Depression. It was also beneficial to college students and Chinese first-time mothers. Meta-analysis using a random-effects model consistently yielded significant score differences between the IPT and control groups (p &lt; 0.0001) on MDD.ConclusionThis systematic review has identified the current best evidence for IPT efficacy in Chinese population. The findings support IPT as an effective treatment in Chinese with certain psychiatric conditions, consistent with those from many other studies throughout the world.
Rate and correlates of self-stigma in adult patients with early psychosis
Authors: Chu Ryan Sai Ting , Ng Chung Mun , Chu Sheung Chit , Lui Tsz Ting , Lau Fu Chun , Chan Sherry Kit Wa , Lee Edwin Ho Ming , Hui Christy Lai Ming , Chen Eric Yu Hai , Lui Simon Sai Yu , Chang Wing Chung 
Published: July 2023

IntroductionSelf-stigma impedes recovery process and is associated with poorer clinical and functional outcomes in people with psychotic disorders. However, there is limited research specifically examining self-stigma in the early stage of illness, and mixed findings were observed regarding factors associated with increased self-stigma. We aimed to investigate the rate and correlates of self-stigma in a cohort of adult patients with early psychosis using a comprehensive array of clinical, treatment and other illness-related variables.MethodsA total of 101 Chinese adult early psychosis patients aged 26–55 years who had received three-year psychiatric treatment for first psychotic episode in Hong Kong and completed self-stigma assessment were included for the current investigation. A broad range of assessments encompassing socio-demographics, premorbid adjustment, onset and illness profiles, symptom severity, psychosocial functioning, treatment characteristics and medication side-effects were conducted.ResultsTwenty-eight (27.7%) patients had moderate-to-high levels of self-stigma. Univariate linear regression analyses showed that age at study entry, sex, educational level, age at psychosis onset, duration of untreated psychosis (DUP), insight level, global psychosocial functioning, and the use of second-generation antipsychotic were related to self-stigma levels. Final multivariable regression model revealed that female sex, younger age at entry, longer DUP and better insight were independently associated with higher levels of self-stigma.ConclusionMore than one-fourth of early psychosis patients experienced significant self-stigma, highlighting an unmet need for early detection and intervention of self-stigma in the initial years of illness. Further investigation is warranted to clarify trajectories and predictors of self-stigma in the early illness course.
Vitamin E intake and multiple health outcomes: an umbrella review
Authors: Zhang Tianyi , Yi Xianyanling , Li Jin , Zheng Xiaonan , Xu Hang , Liao Dazhou , Ai Jianzhong 
Published: July 2023

BackgroundThe benefits of vitamin E (VE) for multiple health outcomes have been well evaluated in many recent studies.ObjectiveThe purpose of this umbrella review was to conduct a systematic evaluation of the possible associations between VE intake and various health outcomes.MethodsWe systematically searched various databases, such as PubMed, Embase, and the Web of Science, to identify related meta-analyses of observational studies and randomized trials. We estimated the effect size of each association by using the random or fixed effects models and the 95% confidence intervals. We used standard approaches to evaluate the quality of the articles (AMSTAR) and classified the evidence into different levels of quality (GRADE).ResultsA total of 1,974 review articles were searched, and 27 articles with 28 health outcomes were yielded according to our exclusion criteria. The intake of VE was inversely associated with the risk of breast cancer, lung cancer, esophageal cancer, gastric cancer, pancreatic cancer, kidney cancer, bladder cancer, cervical neoplasms, cardiovascular disease, Parkinson's disease, depression, age-related cataracts, metabolic syndrome, and fracture. Overall, most of the quality of the evidence was low or very low. Three outcomes (stroke, age-related cataracts, obesity) were identified as having a “moderate” level of quality. The AMSTAR scores for all health outcomes ranged from 5 to 10.ConclusionOur study revealed that VE intake is beneficially related to multiple health outcomes. However, future studies on recommended doses and recommended populations of VE are also needed.Systematic review registrationhttp://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022339571.
Quality of adolescent and youth-friendly sexual and reproductive health services and associated factors in Ethiopia: a systematic review and meta-analysis
Authors: Zenebe Getachew Assefa , Ewunie Temesgen Muche , Belay Moges Mareg , Abose Abinet Meno 
Published: July 2023

BackgroundLow-quality health care services are linked to a variety of health problems, which can have negative effects on adolescent and youth health. As a result, national data is crucial to providing high-quality healthcare to adolescents and youths in order to promote their health, wellness, and growth.ObjectiveTo examine the quality of young people's sexual and reproductive health care services and factors associated with service satisfaction in Ethiopia.MethodsThis review was carried out in accordance with the PRISMA guideline. We reviewed published data related to the quality of adolescent and youth-friendly sexual and reproductive health services (AYSRHS) in Ethiopia from January 02, 2002 to December 30, 2022. Relevant studies were identified through Google Scholar, PubMed, Cochrane Library, Science Direct, and HINARI. The extracted data was imported into STATA version 14.0 software for analysis. Heterogeneity among the reported prevalence of studies was checked using χ2 and I2 tests. The publication bias was examined by Egger's correlation and Begg's regression intercept tests at a 5% significance level.ResultsThe national pooled magnitude of structural, process, and output dimensions of quality of AYSRHS is 54.22% (95% CI: 33.21, 75.24%), 35.44% (95% CI: 24.95, 45.93%), and 57.01% (95% CI: 50.32, 63.7%), respectively. Being female (AOR: 1.61, 95% CI: 1.14–2.27), employed (AOR: 1.82, 95% CI: 1.06–3.14), waiting &lt;30 min to get services (AOR: 2.7, 95% CI: 1.69–4.31), and getting information on the availability of services (AOR: 1.56, 95% CI: 1.15–2.11) were significantly associated with client satisfaction with AYSRHS.ConclusionThe overall magnitude of quality of AYSRHS in the three dimensions is far below WHO quality standards, which are 75 percent for good quality. Sex, employment status, waiting time to get services, and information on the availability of services were significantly associated with client satisfaction with AYSRHS. Therefore, different stakeholders on different levels should work together to strengthen the quality of AYSRHS concidering the above factors.Systematic review registrationIdentifier [CRD42023422667].
Conducting quantitative mask fit tests: application details and affecting factors
Authors: Xu Xiaodan , Zhao Liangliang , Zhu Yong , Du Bing , Zhu Baoli , Zhang Hengdong , Han Lei , Liu Xin 
Published: July 2023

IntroductionRespirators chosen based on their assigned protection factor (APF) enable wearers to effectively reduce particulate matter concentrations to safe levels when used correctly. As a crucial factor in achieving the intended APF, the fit test has become a necessary procedure in respiratory disease protection.MethodsThis study involved 225 participants who underwent a fit test using two reusable types of half masks and two types of full masks. Condensation nuclei counting (CNC) and controlled negative pressure (CNP) were performed.ResultsThe results revealed that the passing rate of full masks was higher compared to half masks. Specifically, the passing rate for the half masks and the full masks were 84.7 and 91.6%, respectively. Gender exerted a statistically significant effect on the passing rate. Nevertheless, age, educational background, and training exhibited relatively negligible effects. Certain movements, such as facing forward, were identified as key actions with strong correlation. Additionally, talking was considered a key action with a high failure rate due to instantaneous leakages. Most participants failed at the initial step of CNP, but nearly all of them passed the fit test using CNC.DiscussionTherefore, putting on full masks, especially for women, provides optimal protection during work. Furthermore, attention should be given to the displacement and deformation of the respirator during the key actions. When it comes to fit test methods, CNC was found to be more practical and comprehensive compared to CNP. Moreover, additional physiological characteristics, such as double chins, could be explored as potential influential factors.
Additions to the Pacific Fauna of Haplomunnidae (Isopoda: Asellota) with Descriptions of Three New Species from the Kuril–Kamchatka Trench Region
Authors: Golovan Olga A. , Malyutina Marina V. , Sharina Svetlana N. 
Published: July 2023

Three new species of the rare deep-sea family Haplomunnidae are described from the abyssal of the Northwestern (NW) Pacific adjacent to the Kuril–Kamchatka Trench (KKT) based on material collected during the deep-sea expeditions KuramBio (2012) and SokhoBio (2015). Previously, only three species of the genus Haplomunna Richardson, 1908 were described in the whole North Pacific, including one species from its western part. Haplomunna kurilensis Golovan and Malyutina sp. nov., closely resembling H. japonica (Gamô, 1983) from the upper hadal of the Japan Trench, was the most numerous haplomunnid species in the studied region. Thylakogaster wilsoni Malyutina and Golovan sp. nov., and Abyssaranea minuta Golovan and Malyutina sp. nov., are the first species of their genera described from the Pacific Ocean. For H. kurilensis sp. nov. and T. wilsoni sp. nov., DNA sequences were obtained for 18S rRNA and 28S rRNA genes. The phylogenetic relationship between these species, as well as their position within the Haplomunnidae, were reconstructed using 18S rDNA.