bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Atmospheric Deposition of Pollutants on the Concentration of Trace Metals on Some Sun-Dried Food Items Dried at a Non-Vehicular Corridor in Ile-Ife Nigeria
Authors: Akinlade Grace Olubumi , Maza Danjuma Dan-Adam , Olabanji Iyabo Oluremi , Ojo Joshua Olufemi 
Published: July 2023

The effect of atmospheric pollution on some sun-dried food items in Ile-Ife, Nigeria was investigated. Six farm produce: cassava (Manihot esculenta), plantain (Musa x paradisiaca), white yam (Dioscorea rotundata), yellow yam (Dioscorea cayenensis), red cocoyam (Xanthosoma sagittifolium) and sweet potato (Ipomoea batatas) were exposed, for different hours (0 h, 8 h, 20 h, 32 h, 42 h), to the sun at a location far from vehicular activities. Exposed samples were digested and analyzed for Cu, Zn, Ni, Mn, Cd, and Pb using Atomic Absorption Spectroscopy (AAS). The concentration of Cu, in exposed samples, ranged from mg/kg in sweet potato (32 h exposure) to mg/kg in cocoyam (0 h exposure), while the concentration of Zn ranged from mg/kg in plantain (42 h exposure) to mg/kg in cocoyam (0 h exposure). On the other hand, the concentration of Mn ranged from mg/kg in plantain (42 h exposure) to mg/kg in sweet potato (0 h exposure). Furthermore, the concentration of Ni ranged from mg/kg in yellow yam (32 h exposure) to mg/kg in the plantain (32 h exposure). The concentration of Cd ranged from mg/kg in cassava (32 h exposure) to mg/kg in plantain (20 h exposure). In comparison, the concentration of Pb ranged from mg/kg in cassava (20 h exposure) to mg/kg in plantain (20 h exposure). The study observed that there was no particular pattern in the effect of atmospheric deposition of the pollutants, Cu, Zn, Ni, Mn, Cd, and Pb, on the concentration of these pollutants in the sun-dried farm products, for the different exposure hours. The study believed that the non-uniform pattern could result from differences in the concentrations of the pollutants in the atmosphere. It could also be a result of the different water retention abilities of the respective farm products, which may impact the absorption or evaporation of deposited pollutants on these farm products.
Rumah Sakit Umum Type C dengan Pendekatan Healing Environment Dampak Pandemi Covid-19 di Binjai
Authors: Prastiwi Miladini 
Published: July 2023

Kesehatan merupakan bagian penting bagi semua orang untuk
menjalankan aktivitasnya, seperti bekerja, belajar dan bermain. Tujuan penelitian yaitu menerapkan konsep healing environment pada sistem pengobatan RSU Bidadari, usulan perbaikan interior ruang rawat inap agar tercapainya konsep healing environment dan mewujudkan rancangan RSU Bidadari di Binjai dengan mendukung usaha penyembuhan pasien yang cepat dengan pendekatan healing enviroment pada ruang rawat inap. Penelitian ini menggunakan metode kualitatif dengan pendekatan psikometri. Hasil analisa penulis berdasarkan studi teoritis terhadap penerapan elemen pencahayaan memiliki kesesuaian dengan apa yang dirasakan pasien ketika berhadapan dengan elemen cahaya dalam ruang rawat inap ini. Para pasien merasa pencahayaan alami yang masuk ke dalam ruangan ini cukup nyaman bagi mata mereka. Di sisi lain, mereka merasa tidak nyaman akan penerapan pencahayaan buatan dalam ruang rawat inap ini.
ANÁLISE DA ADESÃO DE PACIENTES CARDIOPATAS AO PROGRAMA DE REABILITAÇÃO CARDIOPULMONAR E METABÓLICA EM UMA MICRORREGIÃO DE SANTA CATARINA
Authors: Ramezanali Monireh Zimmermann , Venturi Isabela , Medeiros Erick Dieter , Lopes Samantha Cristiane , Baldo Guilherme Valdir , Helbok Ottávia De Vasconcelos Zainho 
Published: July 2023

Objetivo:Evidenciar a adesão de pacientes cardiopatas ao programa de RCPM em uma microrregião do estado de Santa Catarina e a compreensão das adversidades relacionadas. Metodologia: Trata-se de um estudo transversal, realizado a partir da aplicação de um questionário estruturado semi-aberto sobre a história clínica e sociodemográfica de pacientes cardiopatas com indicação ao programa de RCPM. Resultados e discussão:Dos 118 pacientes cardiopatas, 25,4% receberam indicação para frequentar a RCPM, dos quais houve adesão em 73,3% dos casos. As mulheres corresponderam a uma parcela menor dessa totalidade que aderiu ao programa (27,7%). Quanto ao tipo de procedimento invasivo cardiológico relacionado à indicação à RCPM, 56,3% dos pacientes já haviam realizado cateterismo, angioplastia e/ou cirurgia de revascularização cardíaca. Conclusão:Tal qual o cenário global, a atual pesquisa revalida a baixa adesão de pacientes cardiopatas ao programa de RCPM. Como razão determinante, destaca-se a escassa indicação médica à sua aderência após um procedimento invasivo cardiológico. Por fim, reitera-se que além de investimentos em promoção e prevenção à saúde, há a necessidade da constante motivação e atualização médica para suprir tal carência às vistas da redução da morbimortalidade por causas cardiovasculares.
PALAVRAS-CHAVE: Reabilitação Cardiopulmonar e Metabólica. Adesão. Doenças Cardiovasculares.
PREVALÊNCIA DE MICRORGANISMOS IDENTIFICADOS EM ESFREGAÇÕS CERVICO-VAGINAIS DE PACIENTES ATENDIDAS EM UMA UNIDADE BÁSICA DE SAÚDE DO MUNICÍPIO DE JUAZEIRO DO NORTE, CEARÁ
Authors: Barros Paula Fabrícia de Sousa , De Almeida Ray Silva , Leite Pedro Ivo Palacio , Correia Fabrina de  Moura Alves 
Published: July 2023

O objetivo deste estudo foi avaliar a prevalência de microrganismos identificados em exames de citologia oncótica de mulheres em uma comunidade de Juazeiro do Norte, CE. A pesquisa utilizou laudos do período de janeiro de 2013 a julho de 2017 e contou com a análise de 443 registros. A autorização para acesso aos dados se deu através da carta de anuência e do termo de fiel depositário. Trata-se de um estudo transversal documental retrospectivo. A pesquisa utilizou 100% dos registros entre o período de janeiro de 2013 a julho de 2017 presentes no livro de registros. As informações foram agrupadas, analisadas e tabuladas com o programa Microsoft Office Excel 2010. Os resultados evidenciaram maior procura de mulheres entre 25 a 30 anos (20,1%) para a realização do exame. Em 72 laudos foram identificados microrganismos, 49 (65,3%) são referentes Gardnerella vaginalis, a maior incidência foi na faixa etária de 25 a 30 anos com 19 laudos, representando 40% dos casos de Gardnerella vaginalis. Entre os 9 (12,5%) casos de tricomoníase, 4 (44%) remetem a faixa etária de 25 a 30 anos. Candida spp. foi identificada em 7 (9,7%) amostras, sendo mais comum na faixa etária de até 18 anos, com 3 (43%) casos. O HPV esteve presente em 5 (6,9%) laudos. Desta maneira confirma-se a necessidade de ações educativas voltadas para promoção de saúde, proporcionando a compreensão sobre a importância do exame para proporcionar assim uma melhor qualidade de vida para as mulheres que integram esta comunidade.
Palavras- chave: Citopatológico. Microrganismo. Papanicolau
INCIDÊNCIA DE CANDIDÍASE EM CITOLOGIAS REALIZADAS EM UM LABORATÓRIO DE ANÁLISES CLÍNICAS DA CIDADE DE JUAZEIRO DO NORTE- CEARÁ
Authors: Santos Géssica Ribeiro , De Almeida Ray Silva , Bezerra Francisco Yhan Pinto 
Published: July 2023

Objetiva-se analisar a incidência de candidíase em citologias realizadas em um laboratório de análises clínicas da cidade de Juazeiro do Norte-CE. Foram analisados os registros dos exames preventivos realizados pelas mulheres do referido laboratório no período de 2014 a 2017, e foi identificada a incidência de mulheres que positivaram seus laudos para candidíase. Através dosregistros coletados, foi analisado a quantidade de mulheres que realizou o exame, bem como foi caracterizado a faixa etária mais acometida, uma vez que a maior incidência de câncer do colo de útero, entre outras doenças e infecções diagnosticadas, ocorre em mulheres com idade entre 35 a 55 anos. O método de diagnóstico utilizado para verificação das amostras foi o de Papanicolaou. Em relação ao total de mulheres submetidas ao exame com laudos positivos observou-se que o índice de candidíase é mais constante entre mulheres de 26 a 35 anos, representando 7,5% do total de 15,6% dos casos analisados, estando assim relacionados aos fatores de riscos dessa idade. Os resultados do presente estudo revelaram um importante aparecimento de Candida sp em mulheres de 16 a 64 anos, diante do exposto, esse estudo permite concluir que as mulheres entre 26 a 35 anos, apresentam maiores incidências de caso.
Palavras-chave: Candida sp. Incidência. Laboratório.
PENGARUH DOSIS ARANG TEMPURUNG KELAPA DAN KEPADATAN YANG BERBEDA TERHADAP SINTASAN BENIH IKAN MAS (CYPRINUS CARPIO) PADA PENGANGKUTAN SISTEM TERTUTUP
Authors: Satriadi Arman , Rahmawati Aryani , Satria I Nyoman Budi , Soraya Indah 
Published: July 2023

This study aims to determine the effect of coconut shell charcoal doses and different densities on closed system transportation which can increase the survival rate of goldfish (Cyprinus carpio) seeds. The method used in this study is an experimental method and the design used is Completely Randomized Design (CRD). The number of treatments A was divided into 4 levels namely (A1, A2, A3, and A4). Treatment B was divided into 3 levels (B1, B2, and B3) to obtain 12 experimental combinations with 3 repetitions for each combination to obtain 36 experimental units.
The results showed that the highest survival rate of Goldfish (Cyprinus carpio) occurred in Treatment A1B1 (without the addition of coconut shell charcoal), as many as 287 fish/liter of water with an average survival rate (S/R) of 94 .5% and the lowest was A4B2 (with the addition of 45gr of charcoal) of 202 fish/liter of water with an average survival rate (S/R) of 66%
PENGARUH SUHU YANG BERBEDA TERHADAP KELANGSUNGAN HIDUP (SURVIVAL RATE) LARVA IKAN KARPER MAJALAYA (CYPRINUS SP)
Authors: Makrullah Lalu , Rahmawati Aryani , Sumahiradewi Luh Gede , Rizal Lalu Samsul 
Published: July 2023

Intention of this research that is to know influence of different temperature to continuity of carp fish life of majalaya (Cyprinus sp) and to know best temperature to continuity of carp fish life of majalaya. Method which is used in this research is method " eksperiment" that is an research method by performing a some unit activity of attempt to see an result of which is gone domicile and affirm relation I come from among variable perceived or investigated. Result of research of gone of is continuity of highest life that is obtained at treatment of B2 (temperature 28oC) mean equal to 88%, followed by treatment of A1 (temperature 26oC) equal to 85%, treatment of C3 (temperature 30oC) equal to 83,33%, and continuity of mean life of down at treatment of D4 (temperature 32oC) that is equal to 81%
Manajemen Administrasi Pendidikan terhadap Delapan Standar Pendidikan di Sekolah Guna Meningkatkan Kualitas Lembaga Pendidikan
Authors: Munir Alif Syekhul 
Published: July 2023

Manajemen administrasi pendidikan dalam dunia pendidikan diregulasikan dalam pengaturan ketertiban lembaga pendidikan dalam bidang kelayakan operasional, ditandai dengan administrasi pendidikan yang memenuhi syarat. Hasil dalam penelitian ini adalah terdapat tahapan manajemen administrasi pendidikan yang terdiri dari tahapan planning, organizing, actuating, dan controlling. Peningkatan kualitas melalui administrasi pendidikan dalam delapan setandar pendidikan yang terdiri dari tahapan standar isi, standar proses, standar penilaian, standar kelulusan, standar pengelolaan, standar sarana dan prasarana, standar pengelolaan, dan standar pembiayaan. Tahapan planning terdapat perencanaan administrasi pendidikan dalam bidang analisis indikator administrasi pendidikan. Tahapan organizing terdapat pada pembagian tugas terhadap administrasi pendidikan yang diregulasikan oleh lembaga pendidikan melalui peraturan pemerintah dalam bidang pendidikan. Tahapan actuating memiliki tiga fase pelaksanaan yang terdiri dari penyusunan indikator administrasi, pelaksanaan konsep, dan pelaksanaan penilaian administrasi pendidikan. Controlling dalam manajemen administrasi pendidikan yang dilaksanakan dengan tahapan pengawasan secara berkala dalam penyusunan administrasi dan pelengkapan administrasi pendidikan. Tahapan manajemen yang digunakan berpengaruh pada peningkatan kualitas administrasi pendidikan di sekolah, yang digunakan dalam penilaian kualitas sekolah.
La Población de Biar transformada durante las fiestas de moros y cristianos
Authors: Menor Hernandez Andres 
Published: July 2023

El espacio público durane las Fiestas Patronales de moros y cristianos en la localidad de Biar (Alicante) queda transformado desde su uso habitual a un escenario medieval en las calles y plazas donde transcurren los desfiles y procesionesen estos días festivos 10, 11, 12 y 13 de mayo.
Las fiestas de esta localidad han servido de palanca para configurar durante los dos últimos siglos las construcciones de las viviendas. Los recorridos de desfiles y procesiones han revalorizado estos espacios.Por lo tanto, ha habido una conexión directa entre fiestas y urbanismo en la población. Desirée Juliana Colomer en su tesis doctoral ha llegado a la conclusión de que en la ciudad de Valencia en los siglos XVI y XVII hubo una configuración de la ciudad condicionada por los festejos y las procesiones. Guardando las distancias, en Biar también ha habido esta conexión festivo-urbanística.
Psychological flexibility, cognitive emotion regulation and mental health outcomes among patients with asthma in Pakistan
Authors: Hussain Samavia , Khawar Rabia , Amin Rizwana , Hamdani Asma , Majeed Asma 
Published: July 2023

Background/Objective
Adults with asthma who experience difficulties in emotion regulation are prone to developing psychopathological symptoms that may affect their self-management activities and symptom control. The current research investigated the role of psychological flexibility and cognitive emotion regulation strategies in relation to mental health outcomes (psychological distress and quality of life) among patients with asthma in Pakistan.

Method
A sample of 200 adults, diagnosed with asthma (32% men, 68% women; Mage = 42.32, SDage = 16.99), completed the acceptance and action questionnaire (AAQ-II) cognitive emotion regulation questionnaire (CERQ), depression, anxiety, stress scale-21 (DASS-21), asthma-related quality of life questionnaire (AQLQ) and a self-structured demographic sheet.

Results
Results of Pearson product moment correlation showed that most of the adaptive cognitive emotion regulation strategies (positive refocusing, refocus on planning, and positive reappraisal) were positively correlated with psychological flexibility and quality of life, whereas negatively correlated with psychological distress. All the maladaptive strategies of cognitive emotion regulation had a significant inverse relationship with psychological flexibility and quality of life, while positively correlated with psychological distress. Results of serial mediation analysis through PROCESS MACRO showed that catastrophising and anxiety fully mediated the relationship between psychological flexibility and asthma-related quality of life.

Conclusion
Evidence-based interventions should focus on developing psychological flexibility and identifying maladaptive patterns of cognitive emotion regulation strategies for improved mental health and quality of life outcomes for adults with asthma.
Analysis of self-renewing and differentiation-related microRNAs and transcription factors in multilineage mouse hematopoietic stem/progenitor cells induced by 1,4-benzoquinone
Authors: Dewi Ramya , Yusoff Nur Afizah , Abdul Razak Siti Razila , Abd Hamid Zariyantey 
Published: July 2023

Background
HSPCs are targets for benzene-induced hematotoxicity and leukemogenesis. However, benzene toxicity targeting microRNAs (miRNAs) and transcription factors (TF) that are involve in regulating self-renewing and differentiation of HSPCs comprising of different hematopoietic lineages remains poorly understood. In this study, the effect of a benzene metabolite, 1,4-benzoquinone (1,4-BQ) exposure, in HSPCs focusing on the self-renewing (miRNAs: miR-196b and miR-29a; TF: HoxB4, Bmi-1) and differentiation (miRNAs: miR-181a, TF: GATA3) pathways were investigated.

Methods
Freshly isolated mouse BM cells were initially exposed to 1,4-BQ at 1.25 to 5 µM for 24 h, followed by miRNAs and TF studies in BM cells. Then, the miRNAs expression was further evaluated in HSPCs of different lineages comprised of myeloid, erythroid and pre-B lymphoid progenitors following 7–14 days of colony forming unit (CFU) assay.

Results
Exposure to 1,4-BQ in BM cells significantly (p < 0.05) reduced the miR-196b (2.5 and 5 µM), miR-181a (1.25, 2.5 and 5 µM) and miR-29a (1.25 µM) along with upregulation of miR-29a at 2.5 µM. Meanwhile, 1,4-BQ exposure in HSPCs significantly increased the miR-196b expression level (p < 0.05) only in myeloid and pre-B lymphoid progenitors at 2.5 and 5 µM. Significant (p < 0.05) reduction in expression of miR-181a in myeloid (1.25 µM), erythroid (5 µM) progenitors along with miR-29a in myeloid (1.25 µM) and pre-B lymphoid (5 µM) progenitors were noted following exposure to 1,4-BQ. Meanwhile, increased expression of miR-181a was observed in pre-B lymphoid progenitor upon exposure to 1,4-BQ, but only at 5 µM. As for TF studies, expression of HoxB4 protein was significantly increased (p < 0.05) at all 1,4-BQ concentrations as compared to Bmi-1 and GATA3, which were significantly (p < 0.05) elevated starting at 2.5 µM of 1,4-BQ.

Conclusion
1,4-BQ induces aberration of miRNAs and transcription factors protein expression that are involved in regulating self-renewing and differentiation pathways of HSPCs. Moreover, epigenetic toxicity as evidenced from the miRNAs expression was found to be mediated by a lineage-driven mechanism. The role of cell lineage in governing the toxicity of 1,4-BQ in HSPCs lineages deserves further investigation.
Effect of prolactin on cytotoxicity and oxidative stress in ovine ovarian granulosa cells
Authors: Yang Ruochen , Zhang Shuo , Duan Chunhui , Guo Yunxia , Shan Xinyu , Zhang Xinyan , Yue Sicong , Zhang Yingjie , Liu Yueqin 
Published: July 2023

Background
Prolactin (PRL) has been reported to be associated with oxidative stress, which is an important contributor leading to cell apoptosis. However, little is known about the mechanisms underlying the effects of PRL on cytotoxicity and oxidative stress in ovine ovarian granulosa cells (GCs).

Methods
Ovine ovarian GCs were treated with 0, 4, 20, 100 and 500 ng/mL of PRL. Then, the cytotoxicity, cell viability, malondialdehyde (MDA), reactive oxygen species (ROS), superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) of GCs were detected. Additionally, 500 ng/mL PRL was chosen as the high PRL concentration (HPC) due to its high cytotoxicity and oxidative stress. Proteomic and metabonomic were performed to examine the overall difference in proteins and metabolic pathways between C (control: 0 ng/mL PRL) and P groups (500 ng/mL PRL).

Results
The results indicated that GCs treated with 4 ng/mL PRL significantly decreased (P < 0.05) the cytotoxicity, ROS and MDA, increased (P < 0.05) the cell viability, SOD and T-AOC, and the GCs treated with 500 ng/mL PRL showed the opposite trend (P < 0.05). Supplementation with 500 ng/mL PRL significantly increased the proteins of MT-ND1, MAPK12, UBA52 and BCL2L1, which were enriched in ROS and mitophagy pathways. Pathway enrichment analysis showed that the pentose phosphate pathway was significantly enriched in the P group.

Conclusion
A low concentration of PRL inhibited cytotoxicity and oxidative stress. HPC induced oxidative stress in ovine ovarian GCs via the pentose phosphate pathway by modulating the associated proteins MT-ND1 in ROS pathway and UBA52, MAPK12 and BCL2L1 in mitophagy pathway, resulting in cytotoxicity.
Clinical Profile, Severity and Intensive Care needs of Children Admitted with Respiratory Syncytial Viral Infections in PICU: Post COVID Trend
Authors: Philip Bincy , Kavitha T. K. , Najiya  , Gopalan A. V. , Sasidharan K. 
Published: July 2023

Aims: Epidemiology of RSV infection have shown changing trends in the post covid times. Changing pattern in its seasonality have been reported following relaxation of lockdown measures after SARS COVID. Literature describing severity and intensive care needs of pediatric RSV infections are scarce. Our study aims to describe the clinical profile, severity and intensive care needs of pediatric RSV infections requiring PICU admission in post COVID period.
Study Design: Retrospective Study.
Place and Duration of Study: Paediatric Intensive Care Unit of a tertiary care teaching hospital in south India. Study period was from May 2022 and October 2022, over 6 months.
Methodology: All children with clinical diagnosis of viral pneumonia or bronchiolitis were screened. RSV positive cases were taken for the study. The data including age, gender, symptoms, duration of each symptom, respiratory support, duration of oxygen requirement, number of days of PICU stay and outcome of all the children was entered into a structured proforma and data was analysed. The primary objective was to see clinical profile, severity and intensive care needs of RSV affected children aged 1month-12 years admitted in PICU with RSV infections. The secondary objective was to see mortality and length of PICU stay among them.
Results: Out of 36 children with clinical diagnosis of viral pneumonia or acute bronchiolitis, 21 tested positive for respiratory virus, out of which 11 were RSV positive. There was a slight male preponderance. All children were aged less than 18 months. All had respiratory failure and required oxygen support (n=11, 100%). Intensive care needs were high flow nasal cannula requirement in 9 patients (n=9,82%), oxygen via nasal prongs (n=1,9%) and mechanical ventilation (n=1, 9%). Median (IQR) duration of oxygen requirements was 6 (5,9) days. Median (IQR) duration of PICU stay was 6(5,8) days. All 11 children survived.
Conclusion: In the Post Covid era, RSV was the most identified viral etiology behind viral pneumonia or bronchiolitis in our PICU. All children had respiratory failure, which improved with High Flow Nasal Cannula in majority of the children.
Key Points for Clinicians About the SEER Oral Cancer Survival Calculator
Authors: Davies Louise , Hankey Benjamin F. , Wang Zhuoqiao , Zou Zhaohui , Scott Susan , Lee Minjung , Cho Hyunsoon , Feuer Eric J. 
Published: July 2023

ImportanceIn the setting of a new cancer diagnosis, the focus is usually on the cancer as the main threat to survival, but people may have other conditions that pose an equal or greater threat to their life than their cancer: a competing risk of death. This is especially true for patients who have cancer of the oral cavity, because prolonged exposure to alcohol and tobacco are risk factors for cancer in this location but also can result in medical conditions with the potential to shorten life expectancy, competing as a cause of death that may intervene in conjunction with or before the cancer.ObservationsA calculator designed for public use has been released that allows patients age 20 to 86 years who have a newly diagnosed oral cancer to obtain estimates of their health status–adjusted age, life expectancy in the absence of the cancer, and probability of surviving, dying of the cancer, or dying of other causes within 1 to 10 years after diagnosis. The models in the calculator showed that patients with oral cavity cancer had a higher than average risk of death from other causes than the matched US population, and this risk increases by stage.Conclusions and RelevanceThe Surveillance, Epidemiology and End Results Program Oral Cancer Survival Calculator supports a holistic approach to the life of the patient, and the risk of death of other causes is treated equally to consideration of the probability of death of the cancer. This tool may be usefully paired with the other available prognostic calculators for oral cancer and is an example of the possibilities now available with registry linkages to partially overlapping or independent data sets and statistical techniques that allow the use of 2 time scales in 1 analysis.