bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Standardized Clinical Data Harmonization Pipeline for Scalable AI Application Deployment (FHIR-DHP): Validation and Usability Study
Authors: Williams Elena , Kienast Manuel , Medawar Evelyn , Reinelt Janis , Merola Alberto , Klopfenstein Sophie Anne Ines , Flint Anne Rike , Heeren Patrick , Poncette Akira-Sebastian , Balzer Felix , Beimes Julian , von Bünau Paul , Chromik Jonas , Arnrich Bert , Scherf Nico , Niehaus Sebastian 
Published: January 2023

Background
Increasing digitalization in the medical domain gives rise to large amounts of health care data, which has the potential to expand clinical knowledge and transform patient care if leveraged through artificial intelligence (AI). Yet, big data and AI oftentimes cannot unlock their full potential at scale, owing to nonstandardized data formats, lack of technical and semantic data interoperability, and limited cooperation between stakeholders in the health care system. Despite the existence of standardized data formats for the medical domain, such as Fast Healthcare Interoperability Resources (FHIR), their prevalence and usability for AI remain limited.

Objective
In this paper, we developed a data harmonization pipeline (DHP) for clinical data sets relying on the common FHIR data standard.

Methods
We validated the performance and usability of our FHIR-DHP with data from the Medical Information Mart for Intensive Care IV database.

Results
We present the FHIR-DHP workflow in respect of the transformation of “raw” hospital records into a harmonized, AI-friendly data representation. The pipeline consists of the following 5 key preprocessing steps: querying of data from hospital database, FHIR mapping, syntactic validation, transfer of harmonized data into the patient-model database, and export of data in an AI-friendly format for further medical applications. A detailed example of FHIR-DHP execution was presented for clinical diagnoses records.

Conclusions
Our approach enables the scalable and needs-driven data modeling of large and heterogenous clinical data sets. The FHIR-DHP is a pivotal step toward increasing cooperation, interoperability, and quality of patient care in the clinical routine and for medical research.
The effect of cerium dioxide nanocrystals on the prooxidant status of rat lung fibroblasts in vitro under γ-irradiation conditions
Authors:   V. N. Karazin Kharkiv National University, Ministry of Education and Science of Ukraine, Kharkiv, Ukraine, Kot Yu. , Kot K. ,   V. N. Karazin Kharkiv National University, Ministry of Education and Science of Ukraine, Kharkiv, Ukraine, Kavok N. ,   Institute for Scintillation Materials, National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Klochkov V. ,   Institute for Scintillation Materials, National Academy of Sciences of Ukraine, Kharkiv, Ukraine
Published: January 2023

Redox-active nanocrystals of cerium dioxide (CeO2) are of interest as antioxidants; therefore, it is relevant to study the potential ability of these nanocrystals to correct prooxidative markers in irradiated cell culture in vitro. The purpose of the study was to evaluate the effect of redox-active spherical nanocrystals of cerium dioxide on markers of oxidative stress induced by γ-irradiation in a two-dimensional culture of rat lung fibroblasts. Materials and methods. The study was performed on a monolayer of lung fibroblasts of Wistar rats. Nanocrystals were added to the nutrient medium one hour before irradiation until their final concentration in the medium of 2.5 μg/L. The cells were incubated with nanocrystals for one hour and then irradiated. The radiation dose was 0.75 Gy. The concentration of 8-isoprostane was determined by spectrophotometry. The concentration of free oxygen species and the degree of lipid peroxidation in living cells were determined by fluorimetry. Visualization and measurement of fluorescence intensity were performed by confocal laser scanning microscopy. Results. 3 hours after irradiation under the conditions of pre-incubation with CeO2 nanocrystals, the content of reactive oxygen species, the level of lipid peroxidation, and the content of 8-isoprostane were significantly decreased in rat lung fibroblast culture. At the same time, incubation with cerium dioxide nanocrystals much more effectively reduced the content of reactive oxygen species in the cytoplasm of cells than in their nuclei and nucleoli in particular. Conclusion. Preincubation of rat lung fibroblasts in vitro with СeО2 nanocrystals can significantly reduce the oxidizing effects of ionizing radiation.
The effect of living environment on developmental disorders in cold regions
Authors: Liu Yue , Wang Yongchen 
Published: January 2023

Abstract
Developmental disorders (DDs) are a kind of chronic maladies, which can cause serious irreversible detriment to children's physical and mental health. It is predominantly regulated by the interaction of environment and heredity. Cold regions are mainly located in the high latitudes of China. Their living environment is characterized by frequent cold wave, huge temperature difference, severe air pollution, high calorie diet, less exercise, smoking, drinking, etc. In recent years, substantial advances have been made in studies of the correlation between the living environment features in cold regions and the DDs. Accordingly, this article reviews the impact of the peculiar living environment of cold regions on DDs, with a view to provide fresh prevention strategies for reducing the morbidity of DDs in China cold regions by ameliorating living environment.
Aminothiols exchange in coronavirus disease 2019
Authors: Viktorovna Fefelova Elena , Mikhailovna Karavaeva Tatyana , Anatolyevna Parshina Anastasia , Denisovna Ma Van De Vasilina , Petrovich Tereshkov Pavel 
Published: January 2023

Abstract

Objective
Clinical manifestation of the inflammatory process in its relation to biochemical markers (total cysteine [Cys], cysteine-glycine [CysGly], glutathione [GSH], glutamate-cysteine [Glu-Cys], homocysteine [Hcy], the ratio of reduced to oxidized glutathione [GSH/GSSG], the ratio of reduced to oxidized cysteine [CySH/CySS], malondialdehyde-oxidized low-density lipoproteins [MDA-oxLDL]) has been studied in patients with coronavirus disease 2019 (COVID-19).

Material and methods
48 patients with mild to severe COVID-19 and 20 healthy volunteers were included in our research. The participants were divided into 4 experimental groups according to inflammation intensity estimated based on the serum levels of interleukin 6 (IL-6).

Results
All 4 groups showed the prevalence of male patients and elevated serum levels of IL-6 (by 54.6%). There was no comorbidity in patients with mild COVID-19 (nasopharyngitis symptoms) and in healthy control subjects. 50% of patients with lung damage had accompanying diseases. Alterations of aminoethyl metabolism were detected in COVID-19 patients: as reflected by the decreased levels of Cys, CysGly, and Glu-Cys and the increased levels of GSH as compared to the control group.

Conclusion
Elevation of IL-6 over 7.5 pg/mL was associated with decreased GSH/GSSG and CySH/CySS ratios indicating enhanced oxidative stress and was followed by protein oxidation, specifically MDA-oxLDL.
The Influence of Big Five Personality Traits on Perceived Travel Risk and Travel Intention During COVID-19 Pandemic
Authors: Natalia Vanessa Christina , Amelinda Ferrensya , Wijaya Serli 
Published: January 2023

Penelitian ini bertujuan untuk mengetahui pengaruh ciri kepribadian terhadap persepsi risiko berwisata dan minat berwisata wisatawan Indonesia di masa pandemi Covid-19. Ciri kepribadian wisatawan digali dari perspektif teori Big Five Personality Traits. Survei secara daring disebarkan kepada 202 responden yang mengisi kuisioner lewat Google form. Penelitian ini menggunakan SEM-PLS untuk pengolahan data primer. Hasil penelitian menunjukkan bahwa dari lima ciri kepribadian, hanya ciri kepribadian conscientiousness yang berpengaruh signifikan terhadap persepsi risiko berwisata. Persepsi risiko berwisata berpengaruh negatif dan signifikan terhadap minat berwisata. Selanjutnya, persepsi risiko berwisata terbukti merupakan mediator yang signifikan dari ciri kepribadian conscientiousness dan pengaruhnya terhadap minat wisatawan untuk berwisata.

ABSTRACT
This study aims to determine the effect of personality traits on travel perceived risk and travel intention of Indonesian tourists during the Covid-19 pandemic era. The online survey was distributed to 202 respondents who filled out the questionnaire via Google forms. This study uses SEM-PLS for primary data processing. The results showed that of big five personality traits, only conscientiousness trait had a significant effect on perceived travel risk. Tourists’ travel perceived risk had a negative and significant effect on travel interest. Further, tourists’ travel perceived risk was a significant mediator of the conscientiousness personality trait and its influence on travel intention.
The Role of Using Thinking Aloud Pairs Problem Solving (TAPPS) Strategy in Teaching Reading Comprehension to EFL Preparatory School Students
Authors: Hameed Dunia Tahir , Al-Jubouri Hussam R. 
Published: January 2023

Thinking Aloud Pairs Problem Solving has been used as a strategy in teaching reading comprehension. Students should read, re-read silently, think aloud, verbalize what they think, and discuss and share information (work in pairs) to solve problems that are related to the reading passage .This strategy helps students to evaluate their reading which leads them to produce a better comprehension of the text. These aims are supposed to be achieved as follows:

Finding out the role of using (TAPPS) strategy on EFL preparatory school students' achievement in reading comprehension.
Finding out if there is any significant difference between the experimental group's achievement at the recognition and production levels.
الانحياز المعرفي وعلاقته بسمات الشخصية لدى طلبة الجامعة
Authors: Manookh Al-Obaidi Sabah Marshod , Rasheed Al-Shujairi Omar Khalaf 
Published: January 2023

يستهدف البحث الحالي معرفة الانحياز المعرفي وعلاقته بسمات الشخصية لدى طلبة جامعة تكريت ، وكذلك التعرف على دلالة الفروق على وفق متغير النوع (ذكور – إناث). فضلًا عن العلاقة الارتباطية بين المتغيرين ، ومن أجل التحقق من ذلك ، وقد تبنى الباحثان مقياس الانحياز المعرفي المعدّ من (عبد الامير, 2018) إذ بلغ عدد فقراته بصيغتها النهائية (31) فقرة ، وتبنى مقياس سمات الشخصية المعد من قبل (كوستا وماكري 1992). والمعرب من قبل (الانصاري 1997) ، إذ بلغ عدد فقراته بصيغتها النهائية (35) فقرة. وقد تم التأكد من خصائصهما السايكومترية وتم تطبيق الأداتين على عينة بلغت (120) طالبًا تم اختيارهم بالطريقة العشوائية من ثلاث كليات في جامعة تكريت هي (كلية العلوم ، وكلية الآداب ، وكلية التربية للعلوم الإنسانية) للعام الدراسي 2020- 2021 وقد استعانا بالحقيبة الإحصائية للعلوم الاجتماعية (SPSS) في معالجة المعلومات وأظهرت نتائج البحث الآتي:

إن عينة البحث من طلبة جامعة تكريت ليس لديهم انحياز معرفي.
لا توجد فروق ذات دلالة إحصائية بين (الذكور والإناث) في الانحياز المعرفي.
إن عينة البحث من طلبة الجامعة يتمتعون بسمات الشخصية.
توجد فروق ذات دلالة إحصائية بين (الذكور والإناث) في سمات الشخصية ولصالح الذكور.
أظهرت نتائج التحليل الإحصائي أنه توجد علاقة ارتباطية سالبة دالة بين متغير البحث الحالي (الانحياز المعرفي وسمات الشخصية) تبعًا للعينة ككل.
Nigeria’s Energy Crisis and the Sustainability Question
Authors: Jack Jackson , Jack Better 
Published: January 2023

Nigeria’s deepening energy crisis will continue to pose a challenge to the attainment of the United Nations’ Sustainable Development Goals by 2030 despite being the largest producer of oil and gas resources in Africa. With an expanding population of over 200 million people and a rapidly growing economy, the demand for energy has significantly increased over the last decade. However, with a meagre electricity generation capacity of 3 500 to 5 000 MW, only about 53% of Nigeria’s population is connected to the national electric grid accounting for a per capita electricity consumption of 144 kWh, one of the lowest in Africa. To bridge the widening gap between energy demand and supply, millions of Nigerians have continued to rely on unsustainable alternatives such as petroleum-based electricity generating sets to meet domestic, commercial and industrial energy demands. It is against this backdrop that we, by relying on a critical analysis of secondary sources, examined the nature of Nigeria’s energy crisis, the emergent coping behaviour in response to the energy crisis and its impacts on sustainability. We submit that the perennial energy crisis in Nigeria undermines inclusive energy transition and stifles socio-economic growth in the country. Consequent upon this is the emergence of other forms of negative coping behaviour such as artisanal crude oil refining in the oil rich Niger Delta region in which the attendant economic, social, health and environmental implications are most manifest.
Ardahan İli Büyükbaş Hayvancılık Sektöründe Kayıt Dışı İstihdam Bilinç Düzeyi
Authors: EŞTÜRK Özlem , MERT Nilcan 
Published: January 2023

Kayıt dışı ekonomi ve istihdama yansıması olarak kayıt dışı istihdam tüm dünya ülkelerinin karşılaştıkları önemli makro ekonomik problemler arasında yer almaktadır. Türkiye’de kayıt dışı istihdam denildiğinde ağırlıklı olarak tarım sektörü akla gelmektedir. Tarım işletmelerinin kendine has yapısı gereği küçük aile işletmelerinden ve mikro işveren piyasalarından oluşması, yüksek girdi maliyetleri, kırsal alanlarda istihdam imkanlarının kısıtlı olması, kırsalda düşük eğitim düzeyi gibi etkenler tarım sektöründe kayıt dışı çalışma koşullarını yaygınlaştırmıştır.
Kayıt dışı istihdam ülkemizde olduğu gibi Ardahan ili için de önemli meselelerden biridir. Sorunun çözümünde uygulanacak ulusal ve yerel politikalar önem arz etmektedir. Bu çalışma ile Ardahan İlinde büyükbaş hayvancılık sektöründe faaliyet gösteren çiftçilerin kayıt dışı istihdam konusunda farkındalıklarının artırılması, sosyal güvenlik kurumuna kayıtlı olmanın avantajları hakkında bilinç düzeylerinin artırılması amaçlanmıştır. Bu kapsamda 330 kişiye anket yapılarak tam negatif binom regresyon modeli uygulanmıştır. Çalışmadan elde edilen bulgulara göre cinsiyet, yaş, gelir, hanedeki birey sayısı, medeni durum ve hayvancılıktan gelir etme değişkenlerinin bilinç düzeyi üzerinde etkileri olduğu saptanmıştır.
Interference in a Language and Culture Communication
Authors: Gashimov Elchin 
Published: January 2023

International communication is one important aspect in a dialogue of culture and in a process of communication we should concentrate in a problem of the interrelated phenomena of language and culture within the context of bilingual communication. Language and culture interference are important aspect to be considered with regard to teaching of plurilingual learners, whose communicative competence is formed on the basis of several linguistic and cultural systems that interact with each other and exert mutual influence. Interference is an important aspect not only in linguistic, not only in the method of teaching but also in culture too. And after pandemic era we practically have a new view of communication - Online communication, that is defined as perceptual-verbal interaction connected with acts of cognition and creation of meaning-forming systems, manifested in a whole set of principles, among which there are: 1) dialogueness and communicability; 2) visual-perceptual experience; 3) interpersonal communication; 4) a tool for cross-cultural dialogue; 5) a linguistic component.
The Religious Pattern of the Urban Community: a Study on an Nahl Islamic Study Congregation in Pilahan, Rejowinangun Village, Kotagede, Yogyakarta
Authors: Novianti Ida , Hamruni Hamruni , Hamzah Ustadzi , Fauji Sidik , Akhla Gardina 
Published: January 2023

Abstract
Changes in public awareness of the value and appreciation of a religion are characterized by increasing religious awareness in the middle of communal life which is called a social reality. This also happened in the an Nahl Islamic study foundation.This study aims to determine the pattern of religiosity and the background of increasing religiosity in the an Nahl Islamic study congregation. A qualitative study was used in this study, starting from determining the location, subject and object of research, data collection methods, data analysis techniques, and data validity tests that produce data to explore the findings on the diversity of the city's Muslim community which is centered on the an-Nahl recitation congregation who have difference patterns. The emergence of the formation of the religious pattern of the urban Muslim community at the an Nahl Islamic study foundation is influenced by several factors ranging from internal factors, namely factors originating from the individual congregation itself, to external factors in the form of supporting facilities for the implementation of an Nahl Islamic study. There were two religious’ patterns, namely traditional Islam presented by NU and modern Islam presented by Muhammadiyah.
CONTRIBUIÇÃO DA PRAÇA PARA O MICROCLIMA URBANO
Authors: De Oliveira Hyria Fraga , Ramos Larissa Letícia Andara 
Published: January 2023

Devido as atuais dinâmicas e configurações do ambiente urbano, torna-se necessário que a paisagem construída e natural atue de forma equilibrada, garantindo qualidade ambiental ao ambiente construído. As praças – objeto deste estudo – proporcionam benefícios à vida pública urbana, além de influenciar na esfera ambiental. Este artigo enfatiza, através de simulações microclimáticas computacionais, a contribuição da praça para o microclima urbano de área urbana adensada. Tem como recorte de estudo a Praça Bom Pastor, situada em um bairro adensado do município de Vila Velha-ES. Após a revisão bibliográfica, coleta de dados e aferição de temperatura no local para a simulação piloto e calibragem do software, em uma fase sucessiva, foram realizadas simulações da praça e seu perímetro. As simulações foram realizadas no software ENVI-met com o auxílio do plugin Leonardo para confecção dos mapas. As análises avaliaram a temperatura do ar e a temperatura da superfície de dois cenários: cenário real e hipotético, este último considera a praça como um espaço árido. O resultado das simulações demonstrou a contribuição positiva do cenário real da praça – constituída por áreas verdes e materiais de revestimento de superfície permeáveis e semipermeáveis - em comparação ao cenário árido, preenchido por materiais impermeáveis e semipermeáveis.
A Brief Overview and History of Human Nutrition and Health
Authors: Ahsan Haseeb 
Published: January 2023

Nutritional biochemistry is finally getting the attention it deserves, despite the fact that food and nutrition have been studied for centuries. In 1926, less than 100 years ago, the first vitamin was extracted and chemically characterized, leading to studies on single-nutrient deficiency diseases. Nutritional research on chronic diseases like cardiovascular disease, diabetes, obesity, and malignancies has hastened in the past few decades, especially after the year 2000. Nutrition has played a key role in the improvement of public health since the past 200 years, and is expected to play a major role in public health for the future.

Keywords: nutrition, diet, history, food, agriculture.
On Antimagic Labeling for Some Families of Graphs
Authors: Shawkat Noor K. , Ahmed Mohammed A. 
Published: January 2023

Antimagic labeling of a graph with vertices and edges is assigned the labels for its edges by some integers from the set , such that no two edges received the same label, and the weights of vertices of a graph are pairwise distinct. Where the vertex-weights of a vertex under this labeling is the sum of labels of all edges incident to this vertex, in this paper, we deal with the problem of finding vertex antimagic edge labeling for some special families of graphs called strong face graphs. We prove that vertex antimagic, edge labeling for strong face ladder graph , strong face wheel graph , strong face fan graph , strong face prism graph and finally strong face friendship graph .
Pengaruh suplementasi buah dan lama fermentasi terhadap mutu organoleptik kombucha teh hitam
Authors: Shanzet Flavia Fionessa Falenda , Karna Ni Putu Indiani Sahaning , Khairunnisa Nadia , Amelia Ayu , Himawan Alayna , Darmayasa Ida Bagus Gede , Ramona Yan 
Published: January 2023

ABSTRACT
Kombucha is a beverage made from tea as its basic ingredient and fermented by active starter of microbial consortia. The flavor of this fermented beverage is determined by many factors, such as supplementation of the main raw ingredient with various fruits, sugar, and types of tea used as its main raw ingredient. The main objective of this research was to elucidate the effect of fruit supplementation (addition of Fuji apple and strawberry) on the organoleptic quality of the products, following incubation periods of 4, 8, and 12 days. A triplicate complete randomized factorial design (types of fruits combined with incubation period) was applied in the experiment. Organoleptic tests (include taste, aroma, and color of the products) were conducted by applying quisionere method involving 7 panelis. The results showed that types of fruits and incubation period significantly affected (p<0.05) the organoleptic quality of the kombucha products. Overall, combination of stroberry and incubation period of 4 days gave the best results (p<0.05) when compared to control (commercially sold kombucha) and other treatments, indicating that such product has potential to be widely commercialized.
Keywords: Alcohol, fermented beverage, fermentation, kombucha, organic acids
ABSTRAK
Kombucha merupakan minuman hasil fermentasi yang terbuat dari bahan dasar teh setelah diinokulasi dengan mikroba starter. Cita rasa kombucha sangat ditentukan oleh penambahan suplemen, seperti gula, buah-buahan, dan jenis teh yang dipakai. Tujuan utama penelitian ini untuk mengelusidasi pengaruh penambahan jenis buah (buah apel dan buah strobery) dan lama waktu fermentasi (4, 8, dan 12 hari) terhadap kualitas organoleptik produk kombucha yang dihasilkan. Penelitian ini menggunakan rancangan acak lengkap factorial (jenis buah yang dikombinasi dengan lama fermentasi) dengan 3 kali ulangan untuk setiap kombinasi perlakuan. Uji organoleptik (rasa, warna, dan aroma) dilakukan dengan metoda kuesioner yang melibatkan 7 orang panelis. Hasil penelitian menunjukkan bahwa jenis buah dan lama fermentasi berpengaruh nyata terhadap tingkat kesukaan panelis pada produk kombucha. Secara keseluruhan, perlakuan kombinasi penambahan buah stroberi dan waktu fermentasi selama 4 hari memberikan hasil terbaik, dan berbeda nyata dengan kontrol maupun perlakuan lainnya. Hal ini mengindikasikan bahwa produk penelitian ini berpeluang untuk dipasarkan secara luas.
Kata kunci: Alkohol, asam organik, fermentasi, kombucha, minuman terfermentasi
Studi Perhitungan Tahanan Kapal Kontainer 8500 DWT
Authors: Muvariz Mufti Fathonah , Wibowo Sulistyo , Abdurrahman Naufal , Saputra Hendra , Satoto Sapto Wiratno , Yuniarsih Nidia , Pamungkas Nurman 
Published: January 2023

Negara Indonesia adalah negara maritim, Negara yang mempunyai banyak sungai dan lautnya. Dalam proses transportasi antar pulau yang terpisahkan oleh peraiaran, sarana transportasi laut dan sungai sangat dibutuhkan. Untuk menunjang perekonomian negara dan juga sarana transportasi hasil bumi, salah satu alat yang dibutuhkan adalah kapal kontainer. Kapal kontainer adalah kapal yang didesain khusus dan digunakan hanya untuk mengangkut kontainer. Kapal kontainer memiliki desain khusus sesuai ukuran peti kemas yang sudah distandarkan. Untuk menentukan nilai hambatan dan nilai data hidrostatiknya perlu dilakukan pemodelan desain lambung kapal 3D menggunakan bantuan software perkapalan. Metode yang digunakan dalam perancangan desain 3D lambung kapal adalah menggunakan bantuan software maxsurf enterprise v8i. Tujuan dari perancangan kapal ini adalah untuk mengetahui data hidrostatik dan besar hambatan dari bentuk kapal. Dari Perhitungan didapatkan nilai-nilai sebagai berikut : Cb = 0,74, Cm = 0,99, Cwl = 0,844, Cp = 0,7515, Cpv = 0,8815. Diperoleh juga nilai dari Volume Displacement = 9699,37 m3, Besar Displacement = 9941,87 ton dan juga nilai Hambatan Kapal sebesar 221,182 kN.