bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Affecting Recurrence, Metastasis, and Survival in Conjunctival Melanoma
Authors: KARANFİL Feyza ÇALIŞ , GÜNDÜZ Ahmet Kaan , GÜNDÜZ Ömür UÇAKHAN , ATEŞ Funda Seher ÖZALP 
Published: April 2023

Abstract
Purpose: To evaluate clinical and demographic characteristics and factors affecting recurrence, metastasis and survival in conjunctival melanoma (CM).
Methods: The clinical records of 45 patients who were treated for CM between October 1998 and June 2022 were retrospectively evaluated. Age, gender, presence of underlying conjunctival nevus-primary acquired melanosis (PAM),tumor stage according to the 8th edition of the American Joint Committee on Cancer (AJCC) staging system, tumor basal diameter, tumor thickness, lymph node involvement, metastasis, presence of tumor at the surgical margin, treatment method, need for adjuvant therapy, local tumor control, recurrence, and survival were recorded.
Results: Twenty-one (46.7%) patients were female and 24 (53.3%) patients were male. The mean age at diagnosis was 53.2 ±16.1 years. Fifteen (33.3%) patients had conjunctival PAM; 2 (4.4%) patients had conjunctival nevus. The tumor stage was T1 in 24 (53.0%), T2 in 13 (29.0%), and T3 in 6 (13.0%) of the cases. For stage T1 and T2 CM, in addition to excisional biopsy (EB)and cryotherapy, alcohol epitheliectomy (AE) was performed in 17 cases (37.8%), superficial sclerectomy (SS) was performed in 7 (15.6%), and amnion membrane transplantation (AMT) due to a large conjunctival defect in 9 (20.0%). Six (14.0%) T3 cases underwent primary exenteration. Positive surgical margins were observed in 23 (51.0%) of the excised tumors at histopathologic examination. Adjuvant topical mitomycin-C(MMC) was used in 7 (38.9%) and strontium-90 episcleral brachytherapy in 6 (33.3%) of the 23 cases with tumor-positive borders. During the follow-up, recurrence was seen in 14 (31.3%) cases. According to Kaplan Meier analysis, the mean time to recurrence development was 106.3±17.3 months and the 5-year survival rate was 52.0%. Fourteen of the recurrent cases underwent EB+ cryotherapy, 3 underwent AE+SS, and 3 underwent secondary exenteration. Metastasis and lymph node involvement occurred in 11 (25.0%) and 8 (18.2%) of the cases, respectively. Four (8.9%) cases expired. According to Kaplan-Meier analysis, the mean time to metastasis was 119.6±24.1 months and the 5-year survival rate was 52.0%. While recurrence was more frequent in melanomas developing from PAM/nevus, metastasis was more frequent in men and those with lymph node involvement.
Conclusion: Conjunctival melanoma is a malignant tumor with high recurrence and metastasis rates. Precursor nevus/PAM is a risk factor for recurrence, while male gender and regional LN involvement are risk factors for metastasis.
On a Property of Congruence Lattices of Slim, Planar, Semimodular Lattices
Authors: Gr\"atzer George 
Published: April 2023

Abstract

In a 2121 paper with G´abor Cz´edli, we introduced and verified the Three-pendant Three-crown Property, 3P3C, for congruence lattices of slim (no M3 sublattice), planar, semimodular lattices. The proof is very long; in part, because it relies on Cz´edli’s 2021 paper on lamps.
This paper verifies 3P3C using the Swing Lemma, an elementary and short approach.
2020 Mathematics Subject Classification. 06C10.
Global trends and frontiers of research on meibomian gland dysfunction since the millennium: A bibliometric analysis
Authors: cui ge , Yang Jingyuan , Di Yu , Yang Shan , Chen Di , Li Ying 
Published: April 2023

Abstract
Objective To report publication trends since 2000 and identify significant journals, nations, authors associated with meibomian gland dysfunction (MGD) research.Results 1,448 papers published between 1 January 2000 to 1 January 2023 were included. MGD has developed into an incredibly interesting topic (with relative research interest ranging from 0.0005% in 2000 to 0.0082% in 2022). The USA, China, and Japan were the top nations with the most publications, producing the journals, writers, and organizations that published the majority of the literature. The country with the fastest-growing number of publications was China (from 0 in 2000 to 66 in 2022). The journal with the most papers on MGD is Cornea. The most papers were contributed by Arita, Reiko, and Keio University, among writers and organizations, respectively. Dry eye disease and ocular surface were the main topics of earlier study, whereas intense pulsed light (IPL) was the latest hotspot and has been used for the therapy of MGD.Conclusion Our findings may aid in understanding MGD's present and potential future developments. According to the quantity of publications, journals, authors, and institutions, China, the USA, and Japan have the most influence. The IPL, pathophysiology and morphology are highlighted in current research on MGD.
Durability analysis of partial replacement of ordinary Portland cement by white glass waste concrete
Authors: FILHO Mauro José SILVA , SOUZA Madson Lucas , Paiva Vinícius Capistrano , CABRAL Antônio Eduardo Bezerra 
Published: April 2023

Abstract
Concrete consists of cement, water, fine aggregate, coarse aggregate, and air. The cement manufacturing process is responsible for a large carbon dioxide emission. Therefore, several researches have been conducted to find advantageous substitute materials, even if only partially. Waste glass emerges as an alternative because it is a non-biodegradable inert material, with a high recycling rate and low cost. Several studies on recycled glass as a partial substitute for cement in concrete have already been conducted in terms of workability, strength and properties, but few have reviewed the durability properties of concrete incorporating glass waste. It is a fact that durability is of great importance for the performance of concrete, because compromising it can lead to the emergence of pathologies. This article aims to carry out a study on the durability of concrete with the replacement of cement by glass waste, in order to verify its performance in relation to conventional concrete, identifying the advantages that attest to its use in civil construction as an alternative to concrete to be used in buildings, whether in new constructions or in the process of rehabilitation or maintenance.
Study of Enhanced Photocatalytic Efficiency by Field Confinement in Plasmonic Nanostructures for Their Potential Application for Detection of Pathogenic Bacteria
Authors: Qureshi Muhammad Tauseef , Tehseen Aqsa , Iqbal Tahir , Masood Arslan , Afsheen Sumera , Maryam Iqra , Huwaimel Bader , Hameed Reda Abdel , Farghaly Othman , Atta Ayman 
Published: April 2023

Abstract
The interaction of transverse magnetic (TM) plane waves with 1D metallic bowtie gratings on glass substrate has been used for surface plasmon polaritons (SPPs) excitation. Silver (Ag) bowtie metallic grating has been modelled in COMSOL Multiphysics 5.6 Licensed version, for different gap widths (GWs) and film thickness by keeping the periodicity constant. The 0th order transmission spectra for this grating with various geometrical parameters at normal incidence has been extracted and studied by far-field analysis. To check the photocatalytic enhancement, the method of enhanced field confinement is used by exciting SPPs at TiO2/air interface. The enhancement factor is examined by changing gap width (50nm-450nm) with fixed thickness and periodicity. The photocatalytic efficiency is also calculated and degradation of three dyes (Methyl Red (MR), Methyl Orange (MO) and Phenol (Ph)) by calculating their concentrations and photodegradation rate constant ‘k’ are studied as well. Far and near-field analysis are employed to study the optimum structure for effective absorption of light. The results of far-field are supported by applying near-field analysis at resonance wavelength. A brief comparison of enhancement factor and photocatalytic degradation with literature is also presented. This research provides a pathway to real-time applications which are helpful in fabrication of efficient plasmonic based photocatalytic devices for highest degradation efficiency. Such grating devices with optimized parameters can also be used in the field of medical such as biosensor - detection and inhibition of the Pathogenic Bacteria etc.
Analysis of different surface treatments applied to different roofing substrates with an emphasis on water absorption
Authors: MARTINS Antonia Janaína Silva , FONSECA Gabriela Gomes , SILVA Aline Rodrigues , GONZAGA Lídia Bruna Teles , OLIVEIRA Valeria Costa , MORAIS Carlos Drumond Nascimento , PIRES Daniela Giovanini Manuel 
Published: April 2023

Abstract
Roofing systems use different materials that require inclinations according to the typology, shapes and dimensions of the roof, but are exposed to different agents of degradation. In Brazil, it is not common to use treatments to reduce the water absorption of roofs in order to guarantee the performance and durability of roofing systems. This research aimed to determine the water absorption index of ceramic, concrete and fiber cement roofing, according to the effectiveness of two different types of treatments, whose function is to reduce water absorption on the roof of the roofing system. The methodology was based on the analysis of the water absorption in the coverings, in a cyclical way of wetting and drying during 12 days. To meet the cyclical effect, a simulation of rainfall was applied to the roofing systems, with exposure for 45 minutes in each type of roofing with and without the use of two different treatments, that is, a silane-siloxane and an acrylic paint at acrylic resin base. The results indicated that the untreated tiles absorb a high percentage of water when compared to the treated coverings. As for the types of coatings, when analyzed with acrylic paint, they obtained a lower water absorption rate when compared to coatings treated with silane-siloxane. It can be concluded that the use of treatments such as water repellent or acrylic paint on ceramic, concrete and fiber cement coverings reduces their permeability and decreases the rate of water absorption, and the acrylic paint obtained better results in relation to water repellent and roofs not treated.
The Relationship between Dysphagia and Frailty among Chinese Hospitalized Older Patients: A Multiple Mediation Model through Oral Health and Nutritional Status
Authors: Yu Jianjiao , Zhu Huolan , Zhang Yulian , Wang Dan , Guo Hua , Liu Xiaomei , Lai Jin , Zhang Huiying , Xu Huanhuan , Bai Bingyue 
Published: April 2023

Abstract
OBJECTIVES
Frailty contributes to adverse outcomes in older adults and places a heavy burden on healthcare resources. Dysphagia is associated with frailty, but the underlying mechanisms are unclear. This study aimed to investigate the multiple mediating effects of oral health and nutritional status in the relationship between dysphagia and frailty among hospitalized older patients in China.
DESIGN
A cross-sectional study.
SETTING AND PARTICIPANTS
The study was conducted at a university-affiliated tertiary hospital in Xi′an, Shaanxi Province, China from May 2022 to December 2022. A total of 980 patients aged ≥65 years were enrolled.
METHODS
We used the following questionnaires: General Information Questionnaire, Tilburg Frailty Indicators (TFI), Eating Assessment Tool-10 (EAT-10), 30mL Water Swallow Test (WST), Geriatric Oral Health Assessment Index (GOHAI), and Short-Form Mini-Nutritional Assessment (MNA-SF). Descriptive analysis, univariate analysis, multivariate regression analysis, Spearman′s correlation analysis, and mediation effect test were performed using SPSS 26.0 and Mplus 8.3 software.
RESULTS
Dysphagia, oral health, nutritional status, and frailty were significantly correlated (P<0.001). Dysphagia was found to directly affect frailty (β = 0.196, 95%CI = 0.136 ~ 0.257) and through three significant mediation pathways: 1) the path through oral health (β = 0.130, 95%CI = 0.102 ~ 0.162), accounting for 28.14% of the total effect; 2) the path through nutritional status (β = 0.073, 95%CI = 0.046 ~ 0.104), accounting for 15.80% of the total effect; 3) the path through oral health and nutritional status (β = 0.063, 95%CI = 0.049 ~ 0.082), accounting for 13.64% of the total effect. The total mediation effect was 57.58%.
CONCLUSIONS
This study indicated that dysphagia was significantly associated with frailty. Oral health and nutritional status were mediators of this relationship. Improving the oral health and nutritional status of hospitalized older patients may prevent or delay the frailty caused by dysphagia.
PARP1-stabilized FOXQ1 promotes ovarian cancer progression by activating the LAMB3/WNT/β-catenin signalling pathway
Authors: Wu Jiangchun , Wu Yong , Guo Qinhao , Shao Yang , chen Siyu , Liu Chaohua , Lin Kailin , Wang Simin , Zhu Jun , Chen Xiaojun , Ju Xingzhu , Wu Xiaohua 
Published: April 2023

Abstract
Background: Ovarian cancer (OC) is one of the most common fatal malignancies in females worldwide. Only a few articles have reported that Forkhead box Q1 (FOXQ1) is elevated in OC tissues and associated with prognosis, but its cancer-promoting mechanism has not been clarified.
Methods: We analysed the relationship between FOXQ1 expression and clinical prognosis through analyses of public databases and data from our own centre. Subsequently, the carcinogenic effect of FOXQ1 was demonstrated by phenotypic experiments in vitro and in vivo. Mechanistically, downstream transcriptional regulatory molecules and signalling pathways were identified by RNA-seq, ChIP-seq, KEGG and GSEA, and promoter binding sites were identified by luciferase reporter gene assay. The upstream regulatory relationship is explored through Co-IP, immunofluorescence (IF), mass spectrum (MS) and ubiquitination experiments. Finally, this pathway was verified by small animal drug experiments and the relationship between clinical specimens and prognosis.
Results: Here, we show that FOXQ1 is overexpressed in OC and clinically associated with metastasis and patient prognosis. FOXQ1 significantly promotes OC cell proliferation and metastasis in vitro and in vivo. Mechanistically, FOXQ1 can promote LAMB3 transcription by binding to its promoter region. The oncogenic effects of FOXQ1 are mediated by theLAMB3/WNT/β-catenin pathway. Moreover, PARP1 can inhibit the ubiquitination-mediateddegradation of FOXQ1 by targeting the E3 ubiquitin ligase CHIP. Finally, the role of PARP1/FOXQ1/LAMB3/WNT/β-catenin pathway in OC was demonstrated through drug combination experiments in animals and clinical prognosis.
Conclusions: Taken together, our data indicate that FOXQ1, stabilized by PARP1, can promote the progression of OC through the LAMB3/WNT/β-catenin pathway.
Co-evolutionary trade-offs within socioecosystems to adapt to California coastal rewilding
Authors: Levrel Harold 
Published: April 2023

Abstract
This paper aims to describe which institutional, organizational, technical but also ecosystem innovations have led to the adoption of compromises around forms of coexistence between humans and pinnipeds, which have led to the recognition of new rights for the latter. These developments are very heterogeneous depending on the type of socio-ecosystem and that they depend on many factors, ranging from the design of ecosystems, the more or less commercial nature of the issues, and the articulation between private ownership, common property rules and public law. Over the years, innovations have become more systemic in a certain number of sites and have demonstrated some successes, thus offering avenues of reflection for managing the rewilding of territories and the issues of coexistence between humans and non-humans in these territories.
Rb atoms’ Polarization and its gradient estimation for nonresonant light by using Lambert function
Authors: BIRZHANDI SAMANEH 
Published: April 2023

Abstract
Polarization of alkali vapor is a key parameter in the atomic magnetometer's response to the applied magnetic field. In this paper, estimating polarization is used by studying the transmission behavior of the pump beam as a function of intensity. In our study, the transmission of circularly polarized light exhibits nontrivial features such as nonlinear absorption and relaxation. The advantages of this method are its simplicity for characterizing polarization and its accuracy. The intensity and wavelength of the pumping laser are considered for studying polarization changes and polarization gradient. This method could apply directly to the quantum computing in devices like memory, gate, clock, and for reference cell. Also, this method is fast, reliable and accurate and doesn't need on resonance detection which makes it more suitable for ZULF NMR detection.
Could the Trustworthiness in RAndomized Controlled Trials (TRACT) checklist be trusted?
Authors: Alinany Hesham G , AbdelMonem Tamer M , Abdelmeguid Osama S , Sobh Ahmed M , Galal Ahmed F , Elnomrosy  , Rezk Ahmed Y 
Published: April 2023

Abstract
Randomized controlled trials (RCTs) are considered the gold standard study design in clinical effectiveness research, albeit some RCTs have been found to be fraudulent post-publication. The Trustworthiness in RAndomized Controlled Trials (TRACT) checklist examines RCT integrity through an assessment covering seven domains. While the authors claim that it can identify problematic trials, it has never been validated. A critical appraisal of the checklist highlights major failures in terms of health measurement methodology, including the arbitrary nature of items chosen. We applied the checklist to 16 RCTs coauthored by the checklist developer, and identified potential violations related to retrospective registration, ethical implications, authorship, methodology, implausible timeframes, zero participants to follow-up, implausible baseline characteristics, and excessive inter-group within trial as well as inter-trial similarities. In addition, we identified inconsistencies between the trials’ registration and data in the final published manuscripts. If we uncritically assume that the checklist is valid, then a formal institutional investigation into the trial portfolio its developer is warranted; especially targeting these 16 trials objectively shown to be problematic. The checklist should be considered as neither investigative nor conclusive of potential problems with RCTs until it is further refined and validated.
The Fundamental Connection between Energy Supply and Welfare through EROI Values
Authors: Brandes Benedikt Axel 
Published: April 2023

Abstract
Herein I present a simple model on how the nature of energy sources is connected to the welfare of a society. I find that the EROI value of an energy source is the key descriptor for the welfare of an economy and consequently the well-being of its constituents. While the presented model is kept extremely simple, it qualitatively matches historic experiences and allows a view into the future. It also suggests that the longevity of renewable energies is the key factor in their viability as an energy source.
Evaluating the Industry 4.0 Readiness of Dairy Industry: A Case Study in India
Authors: Smiti  
Published: April 2023

Abstract
The world is constantly changing with the advancement in technological changes resulting in a revolution of technology. It has become important for industries to adopt new and advanced technologies to survive. Industry 4.0 (I4.0) is a notion that originated with the German government's technical plan. I4.0 uses cutting-edge technology including artificial intelligence, big data, robots, cloud computing, etc.With a contribution of around 23% to the world's milk output, India is a top producer of the commodity.India has tremendous potential and is the country with the highest global milk production ranking. Successful implementation of I4.0 could bring a technological revolution where machines are connected to internet and thus could interact with each other and with humans. The research paper is a case study for evaluating the readiness level of dairy industry for implementing I4.0. A maturity model, Impuls maturity framework is used to study the readiness level of dairy industry using a survey method in different dairy plants of Delhi/ NCR region, Haryana, Mohali, and Chandigarh.
15 years of research on Google Trends: A bibliometric review and future research directions
Authors: Madsen Dag Øivind , Silva Emmanuel Sirimal , Sohail Shahab Saquib 
Published: April 2023

Abstract
Google Trends is a free analytic tool for measuring and monitoring web search data. Since its introduction in 2006, it has been widely used in research in a variety of academic fields. In this study, we conducted a bibliometric study of the first 15 years of Google Trends research (2007–2022). We extracted bibliometric data from the Scopus database which were then analyzed quantitatively using the Bibliometrix software package. In the paper, two types of analyses are carried out: 1) a citation-based analysis that focuses on the overall publication trends and the identification of the most prolific authors, documents, journals, and countries, and 2) a mapping of themes in GT research and how these have evolved. Overall, the results show that the research on Google Trends has grown considerably in recent years, particularly since the outbreak of the Covid-19 pandemic. Research on GT has also become more diverse in terms of themes, with finance, Covid-19 and other health-related topics being the new dominant areas of research. On the basis of the findings, several areas for future research are outlined.
Bacterial Infection in Head and Neck Space Regions: A Narrative Review
Authors: Lenka Smarita , Rath Shakti , Kumar Swain Santosh , Dubey Debasmita 
Published: April 2023

Abstract:
Head and neck infection (HNI) is more complicated, as most of the sites of infection in this regions are very complex. Bacterial head and neck
infections can usually originate through the upper airway, sinusitis, and dental or oral cavity and then extend deeper into other head and neck
compartment sites. Both aerobic and anaerobic bacteria induce bacterial head and neck infections. This narrative review discusses the bacterial
association, sites of infection, host-pathogen interaction, and secondary complications of head and neck bacterial infection. Staphylococcus aureus,
Klebsiella spp, Escherichia coli, Peptostreptococcus spp., Pseudomonas putida, Pseudomonas aeruginosa, Fusobacterium spp, Citrobacter
freundii, Streptococcus gordonii, Enterobacter spp, Gemella haemolysans, Haemophilus influenzae, and Enterococcus spp., Fusobacterium Spp
are commonly responsible bacteria behind the bacterial head and neck infection (BHNI). Immunosuppression, alcohol consumption, and smoking
risk factors are associated with it. The immune cell maintains a defense mechanism in host-pathogen interaction. Antibiotic-resistant genes in
mucoid biofilm raise multidrug resistance against pathogenic bacteria. Inflammatory condition of the complete head and neck region can be
demonstrated by computed tomography (CT) scan. The secondary complication may lead to induce cancer. Microbial invasions can be bacterial,
fungal, or viral.