bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vitro antiplasmodial and toxicological activities of Vittaria anguste-elongata Hayata extracts
Authors: Hendra Rudi , Khodijah Rohimatul , Teruna Hilwan Yuda 
Published: May 2023

Background: The Vittaria anguste-elongata Hayata fern is a common species that grows on the trunks of palm trees. On the other hand, the phytochemical and pharmacological activities of this specie have not been investigated to a great extent.
Objective: In this study, we reported the invitro antiplasmodial and toxicological activities from a variety of this specie's extract.
Method: Methanol was used to extract the aerial part of the specie, and then a liquid-liquid extraction was done using n-hexane, dichloromethane, and ethyl acetate). Assays for antiplasmodial activity and toxicity were carried out with two different strains of Plasmodium falciparum (3D7 and W2), as well as the brine shrimp lethality test.
Result: The antiplasmodial activities demonstrated that the dichloromethane extract had the most potential antiplasmodial activities among the extracts with an IC50 value of 13.65±0.06 μg/mL. On the other hand, the toxicological activities performed on Artemia salina demonstrated that n-hexane, dichloromethane, and ethyl acetate were all classified as toxic.
Conclusion: These findings provide a foundation for future research into isolating and analysing the biological activity of secondary metabolites found in the extract.
Spinal vascular malformation in a 12 years old child. Diagnostic challenges and management strategies adopting a multidisciplinary approach.
Authors: Das Satyajit , Kursa Gopikrishna , Purkayastha Sukalyan , Nag Subrata , Bharati Ashok , Mukherjee Devdeep 
Published: May 2023

Background: Spinal vascular malformations (SVM) are a complex entity and rarely noted in children. They are commonly seen in the elderly with a predilection for the thoraco-lumbar region. The incidence varies from 3-11% and varies across all age groups. The presenting features in the initial stages are paraplegia, abnormal gait, paraesthesia, radicular pain and diffuse sensory symptoms. If not detected early they can lead to further spinal cord compression and cause urinary retention, bladder, bowel incontinence or erectile dysfunction. Despite the advances in diagnosis and treatment, the complexity of the pathology makes treatment challenging in a child.
Case presentation: We present a 12 years old female child who presented with lower limb weakness, diminished reflexes and urinary retention. Nerve conduction velocity was suggestive of motor axonal neuropathy. Magnetic resonance imaging of spine was suggestive of paraspinal vascular malformation and has recovered after surgical intervention and embolization.
Conclusion: Spinal vascular malformation is extremely rare in children with very few reported cases. A multi-disciplinary approach beginning with a detailed history taking and clinical examination is invaluable in such complicated cases to deal with the various aspects of a complex pathology.
Twenty Year review for Craniofacial Distraction in syndromic craniosynostosis
Authors: De Oliveira Ricardo Santos , Ballestero Matheus , Marques-Netto Paulo Barrero , Andó André 
Published: May 2023

Introduction: Craniosynostosis are cranial deformities resulting from the early closure of one or more sutures. Concomitant facial changes usually result from the involvement of multiple sutures, which may lead to restriction of cranial growth and brain expansion, ocular compression, and breathing difficulties. The distraction osteogenesis (DO)for frontofacial or posterior advancement have increased the safety of the procedure. The aim of this study was a critical evaluation of the use of DO in the surgical treatment of syndromic craniosynostoses, based on the experience of a single craniofacial team.
Methods: Retrospective review of third six patients operated from 2003 to 2022 by the same craniofacial team.
Results: 19 boys and 17 girls were operated, all with rigid distractors. Twenty-nine of them underwent monobloc frontofacial advancement. In seven patient a Le-Fort III/subcranial advancement was performed. A posterior craniofacial advancement was performed in 5. In 11 a fronto-orbital advancement was done in the first year of life. The mean age was 6.0 years (range, 6 months to 13 years). All patients presented with some degree of exorbitism, upper airway obstruction and signs of intracranial hypertension. Cerebrospinal fluid leakage was the most frequent complication (9 cases), pterygomaxillary disjunction was revised in 8, lateral rim orbital fracture in 3 cases, and 3 complication related to the device.
Conclusions: The evolution of surgical techniques allowed DO with rigid distractors to be an important tool for treating the craniofacial issues related to syndromic craniosynostoses. The multidisciplinary team's learning curve is critical to reducing complications associated with osteogenic distraction.
Koreya Respublikasining migratsiya siyosati va uning iqtisodiyotga ta’siri
Authors: Tilavoldiyev Asrorjon 
Published: May 2023

Ushbu maqolada Koreya Respublikasining migrantlarga nisbatan olib borilgan hukumat siyosati va ularning mamlakat iqtisodiy hayotiga ta’siri ko‘rib chiqilgan. Shuningdek, migrantlarning ushbu davlat jamiyati hayotiga moslashish jarayoni, yuzaga kelgan qiyinchiliklar, yaratilayotgan imtiyozlar tahlil qilingan hamda migrant ishchilarning turlarga bo‘linishi va ularga qo‘yilayotgan talablar haqida so‘z yuritilgan.
Changes in cerebral oxygen saturation with the Trendelenburg position and increased intraabdominal pressure in laparocopic rectal surgery
Authors: Alkan Selman , Çakır Murat , Şentürk Mustafa , Varman Alper , Büyükbezirci Gülçin , Aykut Yıldırım Mehmet , Biçer Mehmet 
Published: May 2023

Objective: Position changes and increased intra-abdominal pressure in laparoscopic interventions lead to some physiopathological changes. There is no definite information in the literature regarding cerebral oxygen saturation in patients undergoing colorectal surgery. Our aim was to investigate whether there is oxygen saturation change in the brain tissue in pneumoperitoneum and the Trendelenburg position during laparoscopic rectal surgery.
Material and Methods: Cerebral oxygen saturation was measured in 35 patients who underwent laparoscopic rectal surgery in the Trendelenburg position. Measurements were made under general anesthesia in the pneumoperitoneum and the Trendelenburg position.
Results: The values that are statistically affected by the position are systolic blood pressure, mean arterial blood pressure and cerebral oxygen saturation. The Trendelenburg position does not disturb the cerebral oxygen saturation and it causes an increase in saturation. After pneumoperitoneum occurred, changes in systolic blood pressure, mean arterial blood pressure and brain oxygen saturation were detected. Cerebral oxygen saturation increases with the formation of pneumoperitoneum.
Conclusion: The Trendelenburg position and increased intraabdominal pressure during laparoscopic rectal surgery do not impair brain oxygen saturation.
HUBUNGAN BEBAN DAN STRES KERJA PERAWAT DALAM MENANGANI PASIEN GANGGUAN JIWA DI RUANG UPIP RSUD TGK. CHIK DI TIRO
Authors: Zaman Badrul , Miniharianti Miniharianti , Rabial Jihan 
Published: May 2023

Pendahuluan: Beban kerja perawat berdampak kepada munculnya stres kerja tentu perlu ditinjau lebih lanjut oleh pihak manajemen. Munculnya stres kerja dapat diminimalisir dengan upaya seperti menganalisa perbandingan jumlah pasien dan perawat di ruangan, analisa kesesuaian kemampuan perawat dalam bekerja. Tujuan penelitian ini mengetahui hubungan antara beban kerja dan stres kerja perawat dalam menangani pasien gangguan jiwa di Ruang UPIP RSUD Tgk. Chik Di Tiro. Metode: Penelitian ini bersifat analitik dengan desain cross sectional. Populasi dan sampel dalam penelitian ini seluruh perawat di Ruang Jiwa RSUD Tgk. Chik Di Tiro Sigli yang berjumlah 33 orang. Tehnik pengambilan sampel adalah secara total sampling. Penelitian ini dilakukan pada tanggal 4-14 Juli 2022. Hasil: Hasil uji univariat didapatkan bahwa pendidikan responden mayoritas berpendidikan rendah (90,9%), jenis kelamin mayoritas laki-laki (66,7%), masa kerja perawat mayoritas lama (51,5%), beban kerja perawat mayoritas sedang (57,6%) dan stress kerja perawat mayoritas sedang (57,6%). Hasil uji bivariat diperoleh ada hubungan antara beban kerja dan stres kerja perawat dalam menangani pasien gangguan jiwa (P=0,001). Kesimpulan: Disarankan kepada pihak RSU Tgk. Chik Di Tiro supaya lebih memperhatikan beban kerja dan stres kerja perawat dengan berkurangnya beban kerja dan stres kerja seorang perawat akan berdampak sangat baik pada kinerja seorang perawat.

Kata kunci: Beban Kerja, Gangguan Jiwa, Stres Kerja.
HUBUNGAN KECEMASAN IBU TENTANG ISU HALAL HARAM IMUNISASI DENGAN KEJADIAN KEIKUTSERTAAN IMUNISASI DALAM PEMEMBERIAN VAKSIN PADA BALITA (0-5) TAHUN
Authors: Rehmaitamalem Rehmaitamalem , Maulida Maulida 
Published: May 2023

Pendahuluan: Imunisasi atau vaksin merupakan salah satu cara yang dilakukan untuk memberikan kekebalan pada bayi. Dalam fatwa MUI dijelaskan bahwa Imunisasi pada dasarnya dibolehkan (mubah) sebagai bentuk ikhtiar untuk mewujudkan kekebalan tubuh dan mencegah terjadinya suatu penyakit tertentu. WHO menunjukan tahun 2015 terdapat 19,4 juta anak yang tidak mendapatkan imunisasi. Negara Equatorial Guinea 20%, dan 16% Indonesia menempati urutan ke- 4 dengan persentase 81% setelah Negara Etophia. Saat ini berdasarkan Riset Kesehatan dasar (Rikesdas) tahun 2015, cakupan imunisasi dasar lengkap secara nasional baru mencapai 53,8 %, sedangkan propinsi Aceh baru mencapai 37,0 %. Tujuan penelitian ini untuk mengetahui kecemasan ibu tentang isu halal haram imunisasi dengan kejadian ibu tidak memberi vaksin pada balita (0-5) tahun. Metode: pada Penelitian menggunakan desain penelitian analitik dengan pendekatan crossectional. Penelitian ini telah dilaksanakan di Wilayah Kerja Puskesmas Julok dengan Jumlah Populasi 50 orang responden. Cara pengambilan sampel dalam penelitian ini dilakukan dengan tehnik Total Sampling. Hasil: penelitian menunjukkan bahwa ada hubungan antara Kecemasan ibu tentang isu halal haram imunisasi dengan kejadian ibu tidak memberi vaksin pada balita (0-5) tahun dan didapatkan nilai (P-Value =0,013< 0,05). Kesimpulan: Saran dari penelitian ini diharapkan ibu dapat mencari informasi yang sebenarnya tentang isu halal haram imunisasi tidak hanya percaya terhadap isu – isu yang beredar sekarang ini dan diharapkan bagi Pihak desa yang bersangkuta perlu lebih memperhatikan kembali masyarakat – masyarat nya terutama tenaga kesehatan yang ada didesa seprti pada saat posyandu dan pada saat pemberian imunisasi dasar terhadap anak balita.
PENGARUH PERBEDAAN PELARUT EKSTRAK DAUN MANGGA (Mangifera indica L. var. Arumanis) TERHADAP AKTIVITAS ANTIOKSIDAN DENGAN METODE DPPH (1,1 dyphenyl-2-pikrilhidrazil)
Authors: Seran Ivan Charles , Yulianti Devi Ratna , Ningsih Arista Wahyu 
Published: May 2023

Pendahuluan: Indonesia merupakan salah satu negara dengan varietas mangga terkaya. Tanaman mangga telah dilaporkan memiliki sifat anti-inflamasi, imunomodulator dan antioksidan. Penggunaan tanaman mangga di Indonesia terutama berpusat di sekitar mangga. Meskipun daun mangga sering dianggap limbah dan tidak dimanfaatkan, daun mangga mengandung senyawa aktif mangiferin, polifenol, dan triterpenoid yang memberikan berbagai manfaat bagi daun mangga seperti obat, penyembuhan luka, dll. Metode: Penelitian ini menggunakan ekstrak daun mangga (Mangifera indica L. var. Arumanis) terhadap aktifitas aktioksidan melalui metode DPPH (1,1 dyphenyl-2-pikrilhidrazil) dengan perbedaan pelarut, serta untuk mengetahui nilai IC50 dari ekstrak daun mangga (Mangifera indica L. var. Arumanis) pada masing – masing pelarut. Hasil: Didapatkan hasil penelitian bahwa ekstrak etanol 70% simplisia daun mangga menunjukkan nilai IC50 sebesar 132 ppm (antioksidan sedang), ekstrak etil asetat simplisia daun mangga sebesar 430 ppm (antioksidan lemah), dan ekstrak n–heksana simplisia daun mangga sebesar 842 ppm (antioksidan lemah) hasil tersebut didapatkan di penelitian ini. Kesimpulan: Hal ini menunjukkan bahwa pelarut polar mampu melarutkan komponen senyawa polar maupun nonpolar pada tanaman mangga (Mangifera indica L. var. Arumanis). Pelarut yang berbeda mempengaruhi senyawa mana yang larut dalam proses ekstraksi dan diuji berdasarkan polaritasnya.
PENGARUH RELAKSASI OTOT PROGRESIF TERHADAP INTENSITAS NYERI MENSTRUASI MAHASISWA TINGKAT 2 AKADEMI KEPERAWATAN KESDAM ISKANDAR MUDA BANDA ACEH
Authors: Juwita Ratna , Pertiwi Eri Riana 
Published: May 2023

Pendahuluan: nyeri menstruasi dapat menghambat aktivitas remaja sehingga terjadi penurunan prestasi remaja di sekolah. Dengan pemberian Teknik relaksasi otot progresif. dapat mengurangi serangkaian kontraksi dan menimbulkan relaksasi pada otot tertentu yang dapat mempengaruhi rasa nyeri penelitian ini bertujuan untuk mengetahui pengaruh relaksasi otot progresif dalam menurunkan intensitas nyeri menstruasi. Metode: penelitian ini merupakan penelitian kuantitatif dengan menggunakan quasi eksperiment menggunakan pendekatan one group pre posttest design. populasi dalam penelitian ini adalah mahasiswa TK II Akper Kesdam Iskandar Muda Banda Aceh sebanyak 239 orang, dan jumlah sampel sebanyak 42 orang yang dipilih secara purposive sampling. Terapi ini diberikan pada hari pertama sampai hari ketiga menstruasi, dilakukan dua kali dalam satu hari sebanyak 15 gerakan selama 30 menit. Intensitas nyeri menstruasi diukur menggunakan skala numerik dan dianalisis dengan uji paired t-test dan uji independent samples t-test. Hasil: Hasil Penelitian ini mayoritas responden berusia 20 tahun mencapai 54,8%, usia menarche mayoritas responen 12 tahun mencapai 31,0%, lama menstruasi mayoritas responden 1 sampai 6 hari mencapai 71,4% dan durasi nyeri mayoritas responden 3-4 hari mencapai 52,4 %. Teknik relaksasi otot progresif efektif dalam mengurangi nyeri menstruasi (ρ=0,000). Kesimpulan: Teknik relaksasi otot progresif efektif dalam mengurangi nyeri menstruasi. Diharapkan keluarga dan tenaga kesehatan dapat terlibat dalam menerapkan Teknik relaksasi otot progresif pada remaja untuk mengurangi nyeri menstruasi.
Analytic Network Process (ANP) Method: A Comprehensive Review of Applications, Advantages, and Limitations
Authors: Taherdoost Hamed , Madanchian Mitra 
Published: May 2023

Nowadays, multi-criteria decision-making (MCDM) methods possess manifold applications in many areas from engineering to supply chain and management. The analytic network process (ANP) method is one of the most widely used MCDM methods. ANP is an extended version of the analytic hierarchy process that enables feedback and interactions between and within clusters, making it a more comprehensive decision-making tool. This paper provides a detailed review of the ANP method, including its concept, process steps, application areas, advantages, and limitations. ANP has been applied to a wide range of decision-making problems, including project management, risk assessment, supplier selection, and product design. ANP's main advantages include its ability to handle complex decision-making problems with multiple criteria, subjective inputs, and interdependent relationships among criteria. This paper aims to provide a comprehensive understanding of the ANP method to help researchers and practitioners make more informed decisions when using this technique.

Received: 22 March 2023 | Revised: 4 May 2023 | Accepted: 16 May 2023

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
Understanding the structures of Pier Luigi Nervi: a multidisciplinary approach
Authors: Lenticchia Erica , Ceravolo Rosario , Faccio Paolo 
Published: May 2023

The paper describes the strategies adopted to carry out the knowledge campaign on Hall C built by Pier Luigi Nervi at Torino Esposizioni, between 1949 and 1950, and belonging to the architectural heritage of the 20th century. The structure was built by combining reinforced concrete and ferrocement elements, thus implementing what for Nervi would later become the distinctive construction system of his artwork, which combined the use of precast in situ and cast-in-place elements.

The extensive review of the historical documentation allowed the identification of the distinctive features and material differences of all structural elements in order to formulate the least invasive testing campaign possible, combining sample extraction with non-destructive testing. The paper aims to illustrate the problems and challenges associated with the creation of interpretive models of the built heritage through the relationship between historical critical investigations and structural diagnosis and is intended to serve as an example for an appropriate phase of investigation aimed at developing guidelines for the conservation of a complex and iconic work.
CHẤT LƯỢNG CUỘC SỐNG CỦA BỆNH NHÂN GÃY XƯƠNG HÀM MẶT TRƯỚC VÀ SAU PHẪU THUẬT
Authors: Bùi Xuân Đạt , Nguyễn Văn Dũng , Nguyễn Thị Hảo , Nguyễn Hoàng Thanh 
Published: May 2023

Đặt vấn đề: Chấn thương Gẫy xương hàm mặt (GXHM) là một tổn thương thường gặp trong bệnh cảnh chấn thương nói chung. Chấn thương dễ để lại những di chứng ảnh hưởng đến thẩm mỹ khuôn mặt và tâm lý người bệnh (NB), gây tác động tiêu cực đáng kể đến chất lượng cuộc sống (CLCS). Mục tiêu: mô tả chất lượng cuộc sống của bệnh nhân trước và sau phẫu thuật chấn thương hàm mặt. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 60 NB được PT GXHM tại Bệnh viện E từ tháng 7/2021 đến tháng 4/2021. Đánh giá CLCS của NB bằng thang điểm OHIP-14 VN. Kết quả: Điểm trung bình CLCS theo thang điểm OHIP-14 VN tại thời điểm sau phẫu thuật 1 tháng là 10,83 ± 4,37 thấp hơn trước phẫu thuật 24,40 ± 10,37, sự khác biệt là có ý nghĩa thống kê với p < 0,001. Tỷ lệ bệnh nhân có chất lượng cuộc sống kém giảm từ 85% trước phẫu thuật xuống còn 26,7% sau phẫu thuật 1 tháng. Kết luận: Chất lượng cuộc sống của bệnh nhân chấn thương hàm mặt được cải thiện đáng kể sau phẫu thuật 1 tháng.
Penerapan Psychological Appraisal Pada Sistem Penilaian Kepegawaian Berbasis Website Dengan Metode Simple Additive Weighting (Studi Kasus PT. Harto Mulia Pratama)
Authors: Pratama Handika , Syakti Firamon 
Published: May 2023

Psychological Appraisal merupakan suatu metode yang di gunakan untuk menemukan potensi tersembunyi dari seorang karyawan suatu organisasi atau perusahaan. Psychological Appraisal meliputi hal–hal seperti Skill Interpersonal, Kognitif, Intelektual, Kepribadian dan Emotional. Psychological Appraisal dapat di terapkan pada Sistem Pengambilan Keputusan Peniliaian Karyawan yaitu sebuah sistem yang di gunakan untuk menilai kinerja dari karyawan, dimana perusahaan atau organisasi menggunakan sistem ini untuk mengevaluasi. memotivasi, memverifikasi dan meningkatkan kinerja dari karyawan. Hasil Penilaian dari sebuah Sistem Pendukung Keputusan Penilaian Kinerja yang menggunakan metode Psycholocal Appraisal ini dapat menjadi alat bantu dalam memberikan promosi jabatan, pemberhentian, mutasi, pemberian bonus atau reward kepada karyawan / pegawai. Untuk Proses Perhitungan pada Sistem Penunjang Keputusan untuk penilaian karyawan pada PT. Harto Mulia Pratama ini menggunakan metode Simple Additive Weigthing (SAW) yaitu dengan melakukan proses pembobotan pada masing – masing kriteria pada Psychological Appraisal yang akan menghasilkan Benefit dan Cost. Dari hasil perhitungan masing – masing karyawan mulai dari Rating Kinerja Ternormalisasi, perhitungan Normalisasi dan Nilai Preferensi serta dilakukan proses Perangkingan didapat karyawan dengan nama Dika Wahyudi sebagai peringkat pertama dengan nilai 0.743651
Extrapolating Clinical Evidence Within Economic Evaluations
Authors: Coyle Doug , Haines Alex , Lee Karen 
Published: May 2023

Extrapolation is a fundamental part of many economic evaluations, though there are numerous methods of extrapolating the same dataset. The method that is most appropriate for the decision problem is contingent on several factors.
From the literature, recommendations for best practices when it comes to the extrapolation of clinical data have been identified. These pertain to validation of output, use of external evidence, treatment waning, proportional hazards, characterization of uncertainty, reporting of results, and choice of decision model.
Gaps remain in the literature that require further research regarding what is the minimum amount of data to extrapolate reliably and how to robustly extrapolate relative effects for multiple treatment comparisons.
The Relationship Of Diet Compliance With Blood Sugar Levels In Type 2 Diabetes Mellitus Patients
Authors: Suryatin Etin , Rohimah Siti , Rosdiana Nina 
Published: May 2023

Purpose: This study aims to determine the relationship between dietary adherence and blood sugar levels in patients with type 2 diabetes mellitus at the UPTD Panawangan Health Center.
Methods: This research method uses a cross-sectional study approach, with a sample of 80 respondents, as well as a proportional random sampling technique, and the measuring the instrument used is a questionnaire and a digital blood sugar checker (Easy Touch GCU 3 in 1).
Results: The results of the analysis of this study showed that most of the respondents adhered to the diet as many as 41 people, did not comply as many as 39 people. The results of the statistical analysis of Rank Spearman obtained that Ha could be accepted.
Conclusion: This study concludes that there is a relationship between dietary adherence and blood sugar levels in diabetes mellitus patients at the UPTD Panawangan Health Center, Ciamis Regency.
Pengaruh Literasi Keuangan dan Gaya Hidup Terhadap Perencanaan Keuangan Pegawai Kantoran di Tangerang Raya
Authors: Nur Assyifa Charlina , Subagyo Herry 
Published: May 2023

Perencanaan pada dasarnya membantu seseorang dalam mewujudkan tujuan keuangan yaitu merdeka secara finansial. Perencanaan keuangan membantu seseorang meningkatkan pendapatan dengan tabungan dan investasi, juga mengalokasikan uang yang dimiliki ke berbagai sektor, baik itu kebutuhan pokok maupun santai. Kebutuhan santai erat kaitannya dengan gaya hidup. Perencanaan keuangan yang benar membutuhkan literasi keuangan yang baik agar gaya hidup tetap stabil. Penelitian ini memiliki tujuan guna meneliti relasi antara literasi keuangan dan gaya hidup terhadap perencanaan keuangan pegawai Kantoran di Tangerang Raya serta mengetaui perbedaan ketiganya. Sampel berjumlah 100 pegawai. Penelitian ini merupakan penelitian kuantitatif dengan penyebaran kuisioner sebagai teknik pengumpulan data. Analisis menggunakan teknik analisis regresi linear berganda guna diketahuinya pengaruh variabel independen dan dependen. Data dianalisis menggunakan uji normalitas, multikolinieritas, heteroskedstisitas, analisis linear berganda, uji t, uji F serta koefisien determinan (R2). Penelitian ini menghasilkan bahwa variabel literasi keuangan tidak berpengaruh terhadap perencanaan keuangan, sedangkan variabel gaya hidup berpengaruh terhadap perencanaan keuangan pegawai kantoran di Tangerang Raya. Kedua variabel yakni literasi keuangan (X1) dan gaya hidup (Y) secara simultan signifikan memiliki pengaruh terhadap perencanaan keuangan pegawai Kantoran di Tangerang Raya.