bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pressure and temperature dual-parameter optical sensor based on the MIM waveguide structure coupled with two T-shaped cavities
Authors: Zhang Xinyi , Tian He , Liu Yajie , Song Jiaqi 
Published: August 2023

This paper elaborates on the design and simulation of a multifunctional optical sensor that features simultaneous detection of pressure and temperature, which is based on the metal–insulator–metal waveguide structure with two T-shaped resonant cavities. Depending on the simulation findings, pressure and temperature can be measured separately by two T-shaped cavities at different Fano resonance wavelengths. As the pressure applied to the upper T-shaped cavity increases, the resonance wavelength first shifts linearly due to the slight deformation of the cavity, and the maximum pressure sensitivity reaches 12.48 nm/MPa. After the pressure exceeds a threshold, the relationship between pressure and resonance wavelength transforms into a quadratic polynomial. In the lower T-shaped cavity, solid polydimethylsiloxane is sealed as a thermal-sensitive material, effectively preventing material overflow brought on by structural micro-vibration under pressure, and its high thermo-optical coefficient prompts a temperature sensitivity of 0.36 nm/°C. Furthermore, by optimizing the choice of Fano resonances, pressure and temperature can be sensed independently without mutual interference. The designed sensor provides extensive application possibilities for scenarios where multiparameter monitoring is required.
Measurement of differential mode group delay in few-mode fibers based on Fresnel reflection peaks
Authors: Pang Aodi , Hu Guijun , Qin Yi , Wang Haiyan 
Published: August 2023

Mode-division multiplexing communication based on few-mode fibers (FMFs) is the most competitive scheme to address the bandwidth exhaustion in single-mode fibers. The differential mode group delay (DMGD) among different modes in FMFs is an important aspect in characterizing FMFs, and the convenient, fast, and accurate measurement of DMGD in different modes of FMFs is a crucial task. This paper presents a single-ended measurement method for DMGD in FMFs based on Fresnel reflection peaks. Experimental measurements were conducted to determine the DMGD of a 3.689 km six-mode fiber and a 9.7 km three-mode fiber, and the results were compared with the traditional time-of-flight method. The findings demonstrate that our proposed method based on Fresnel reflection peaks exhibits good accuracy in measuring the DMGD of FMFs. Moreover, this method enables single-ended measurement and offers simplicity and practicality.
Cavity-enhanced scalable integrated temporal random-speckle spectrometry
Authors: Xu Hongnan , Qin Yue , Hu Gaolei , Tsang Hon Ki 
Published: August 2023

Chip-scale integrated spectrometers have many prospective applications, such as in situ biochemical analysis, optical coherence tomography, and remote hyperspectral sensing. Most reported monolithically integrated spectrometers support spectral resolutions of 101−102pm with 102−103 wavelength channels. In this work, we propose and demonstrate a scalable integrated spectrometer that achieves ultrahigh resolution and improves the channel capacity by around one order of magnitude. The approach is based on a spatially reconfigurable multimode cavity formed by a waveguide array and delay lines. The mode mixing is enhanced through cavity resonance and intermodal coupling, producing chaotic spectral responses. The orthogonal resonant state can be arbitrarily switched by tuning the phase shifters within the cavity. Each wavelength channel is associated with a unique random temporal speckle. Notably, for the proposed design, all the speckle “signatures” can be detected at a single spatial port and generated purely in the time domain, resulting in an extremely large number of usable speckles (>2×104) beyond the capacity limit of multimode interference. Any arbitrary input spectrum can be computationally retrieved from the recorded output signal. Due to the full randomization of the singular space, the sampling steps can be decreased to <2×103, which efficiently reduces the computational requirement. Our experimental results show an ultrahigh resolution of 5 pm over >2×104 wavelength channels, with a peak signal-to-noise ratio of ≈30dB. To the best of our knowledge, these results represent the largest channel capacity among all demonstrated monolithically integrated spectrometers.
Association between dietary magnesium intake and peripheral arterial disease: Results from NHANES 1999–2004
Authors: Wu Zhe , Ruan Zhishen , Liang Gang , Wang Xu , Wu Jianlin , Wang Bin 
Published: August 2023

Background
Magnesium has been found to have a strong association with peripheral arterial disease (PAD), and dietary magnesium intake shows promise as a predictor of the condition. However, the relationship between low dietary magnesium intake and an increased risk of PAD remains uncertain, and further research is needed to clarify this relationship.

Methods
This study analyzed data from 5969 participants in the National Health and Nutrition Examination Survey (NHANES) of the United States from 1999 to 2004. Multifactorial logistic regression models were used to investigate the association between dietary magnesium intake and PAD.

Results
Participants with PAD had lower dietary magnesium intake compared to those without PAD. After adjusting for all covariates, dietary magnesium intake remained negatively associated with PAD (OR: 0.999, 95% CI: 0.998, 1.000). When dietary magnesium intake was divided into quartiles, compared with the fourth quantile, the first quartile is associated with a higher incidence rate of PAD (OR: 1.560, 95%CI: 1.019, 2.386). Subgroup analysis revealed that the link between dietary magnesium intake and PAD remained significant among specific subgroups, including non-white, never or former smokers, and non-hypertensive, non-diabetic individuals (P < 0.05).

Conclusion
Our study provides evidence that dietary magnesium intake is negatively associated with the incidence of PAD. Therefore, people with inadequate dietary magnesium intake, particularly those with excessively low intake, should increase their magnesium intake to reduce the risk of PAD.
Electronic patient-reported outcome (ePRO) application for patients with prostate cancer
Authors: Mohseni Majid , Ayatollahi Haleh , Arefpour Amir Mohammad 
Published: August 2023

Introduction
Cancer patients experience different complications and outcomes during or after medical treatments. Electronic reporting of the outcomes by patients is a solution that facilitates communication with physicians and improve patient health status. The aim of this study was to develop a smartphone-based application for electronic reporting of outcomes by patients with prostate cancer.

Methods
The present research was conducted in 2021 in two phases. In the first phase, initially, users’ requirements were identified based on reviewing the related literature, existing applications, and guidelines. Then, a questionnaire was designed and the specialists’ opinions about the users’ requirements were investigated. The specialties included urologists, hemato-oncologists, uro-oncologists, and radiotherapists (n = 15). In the second phase, the application was designed, and patients with prostate cancer (n = 21) and specialists (n = 10) evaluated it using the post-study system usability questionnaire (PSSUQ). Data were analyzed using descriptive statistics.

Results
The findings of the first phase of the research showed that out of 108 data elements and functions proposed for the application, 91 items were found essential by the specialists. Data elements were categorized into the patient data, general complications of prostate cancer and side effects of drug therapy, surgery, chemotherapy, cryotherapy, radiation therapy, and hormone therapy. Necessary functions for the application included presenting a patient care summary, communication between the patient and the specialist, free text explanation for complications and sides effects, generating reports, reminder and alert, completing quality of life questionnaire, and calculating the score for the questionnaire. In the second phase of the research, the application was developed and evaluated. The mean value for user satisfaction was (5.95 ± 0.55) out of 7.

Conclusion
The developed application can help to accelerate communication with the specialists. It can improve quality of care, reduce unnecessary treatment visits and side effects, and improve timely data collection for a variety of research purposes. However, further research on the cost-effectiveness and usefulness of the collected data is recommended.
S-1 and 5-Fluorouracil-related adverse events in patients with advanced gastric cancer: A meta-analysis
Authors: Hu Qingqing , Xu Jiajia , Ke Jingshu , Zhang Ziye , Chu Ting 
Published: August 2023

Objective
To assess S-1 and 5-fluorouracil (5-FU)-related adverse events in patients with advanced gastric cancer and provide focused health care approaches to improve patient compliance and quality of survival.

Methods
The PubMed, Web of Science, Medline, Cochrane Library, EMbase, SinoMed, Wan Fang Data, CNKI, and VIP databases were searched, and relevant literature was screened from the database construction date through March 31, 2023. Review Manager 5.4.1 and Stata 12.0 were used to analyze the data and GRADEpro was used to assess the quality of the literature. Relative risk ratio (RR) and a 95% confidence interval (CI) were employed as markers to compare adverse events due to S-1 vs 5-FU.

Results
Eight randomized controlled trials (RCT) were included, which contained 3,455 patients. The S-1 group had 1,804 patients, and the 5-FU group had 1,651 patients. There were 17 recorded adverse events in total. Stomatitis, hypokalemia, mucosal inflammation, and hypophosphatemia were more common in the 5-FU group than in the S-1 group (P < 0.001). No significant difference was observed between S-1 and 5-FU for other adverse events.

Conclusions
Although both S-1 and 5-FU cause a variety of side effects, 5-FU resulted in a higher incidence of stomatitis, hypokalemia, mucosal inflammation, and hypophosphatemia than S-1. Medical professionals should closely monitor the occurrence of adverse drug events and provide timely, rational guidance and nursing care to improve patient compliance and quality of life.
Arterial leg ulcers—Bacterial patterns, antimicrobial resistance and clinical characteristics, a retrospective single-centre cohort, 2012–2021
Authors: Salm Jonas , Böhme Tanja , Noory Elias , Beschorner Ulrich , Kramer Tobias Siegfried , Westermann Dirk , Zeller Thomas 
Published: August 2023

Objective
Severe wound infections in patients with peripheral artery disease (PAD) are common, potentially life- and limb-threatening, and difficult to treat. Evidence on patients with infected leg ulcers in PAD is scarce. This study aims to provide insight into the microbiological patterns and antimicrobial resistance (AMR) of specific pathogens in patients with arterial leg ulcers.

Methods and design
In this retrospective, consecutive, single-centre study 16,553 patients underwent an endovascular revascularization procedure between 2012 and 2021. Of these, 1,142 patients had PAD Rutherford category 5 or 6 with infected leg ulcers. Logistic regression was used to identify risk factors for Staphylococcus aureus-associated infections.

Results
A total of 3,431 bacterial isolates were detected, of which 2,335 (68.1%) bacterial isolates were gram-positive and 1,096 (31.9%) were gram-negative species. The most prevalent bacteria were S. aureus (18.6%), Enterococcus faecalis (9.1%) and S. epidermidis (7.8%). Pseudomonas aeruginosa (5.6%), Proteus mirabilis (3.7%) and Escherichia coli (3.4%). The resistance of S. aureus isolates to clindamycin was 11.0%. Resistance to oxacillin was rare (1.5%). P. aeruginosa is frequently resistant to ciprofloxacin (14.4%) whilst intrinsically resistant to trimethoprim/sulfamethoxazole. P. mirabilis and E. coli were frequently resistant to both ciprofloxacin (7.3; 20.7%) and trimethoprim/sulfamethoxazole (24.6; 22.6%), respectively. Resistance to amoxicillin/clavulanic acid was high among E. coli isolates (36.8%). Multi-drug resistance (MDR) was rare among S. aureus and P. aeruginosa isolates. In contrast, the proportion of MDR was high in E. coli isolates. End-stage renal disease was independently positively associated with S. aureus identification (p = .042).

Conclusion
S. aureus was the most common pathogen in arterial leg ulcers with end-stage renal disease being an independent risk factor. Clindamycin resistance was common, making empirical therapy likely to fail. Isolated E. coli species had a high proportion of MDR.
Gas Embolism After a Patient's Ninth ERCP Procedure
Authors: Ahmad Helal Said , Cohen Sari Anne , Khoury Tawfik , Tome Riad , Zeibak Haitam , Abboud Wisam , Mari Amir 
Published: August 2023

ABSTRACT
Gas embolism is a rare and potentially fatal complication of endoscopic retrograde cholangiopancreatography (ERCP). We present a 66-year-old man who developed gas embolism after undergoing therapeutic ERCP for cholangitis. Some risk factors of gas embolism in this patient included stones in the common bile duct with cholangitis and a history of multiple ERCP procedures. Early diagnosis and rapid treatment of this potentially fatal complication resulted in our patient's full recovery.
Polyhedral compactifications, I
Authors: Ciobotaru Corina , Kramer Linus , Schwer Petra 
Published: August 2023

Abstract
In this work we describe horofunction compactifications of metric spaces and finite-dimensional real vector spaces through asymmetric metrics and asymmetric polyhedral norms by means of nonstandard methods, that is, by ultrapowers of the spaces at hand. The polyhedral compactifications of the vector spaces carry the structure of stratified spaces with the strata indexed by dual faces of the polyhedral unit ball. Explicit neighborhood bases and descriptions of the horofunctions are provided.
Characterizations for the genuine Calderón-Zygmund operators and commutators on generalized Orlicz-Morrey spaces
Authors: Guliyev V. S. , Omarova Meriban N. , Ragusa Maria Alessandra 
Published: August 2023

Abstract
In this article, we show continuity of commutators of Calderón-Zygmund operators

[

b
,
T

]

\left[b,T]

with BMO functions in generalized Orlicz-Morrey spaces

M

Φ
,
φ

(

R

n

)

{M}^{\Phi ,\varphi }\left({{\mathbb{R}}}^{n})

. We give necessary and sufficient conditions for the boundedness of the genuine Calderón-Zygmund operators

T

T

and for their commutators

[

b
,
T

]

\left[b,T]

on generalized Orlicz-Morrey spaces, respectively.
Open Economy Neoclassical Growth Models and the Role of Life Expectancy
Authors: Tserenkhuu Tselmuun , Kosempel Stephen 
Published: August 2023

AbstractThis paper applies the Ramsey–Cass–Koopmans (RCK) growth model to an open economy so that, when calibrated with standard parameter values that are commonly used in the small open economy macroeconomic literature, the time paths of the model variables and the speeds of convergence implied by the model conform with empirical evidence. Open-economy versions of the RCK growth model lead to several counterfactual conclusions including: infinite speeds of convergence for physical capital and output; and unbalanced consumption and asset growth. We avoid these undesired results by extending the baseline model with human capital, international credit constraints, and finite horizons. Given its finite-horizons feature, our model allows us to study the growth implications of changes in life expectancy from the perspective of an open economy, as most of the existing theoretical-quantitative literature that focus on the relationship assumes a closed economy. The model predicts that increased life expectancy has positive but diminishing marginal effect on long-run output per capita. We find that, between 1960 and 2018, improvements in average life expectancy at birth raised long-run output per capita in sub-Saharan Africa, the OECD region, and Canada by an estimated 57.49 %, 14.94 %, and 11.58 %, respectively. In addition, if average life expectancy at birth in sub-Saharan African countries converges from its current level to the level in their OECD counterparts, the region’s long-run output per capita will increase by an estimated 22.89 %.
Application and teaching of computer molecular simulation embedded technology and artificial intelligence in drug research and development
Authors: Chen Xiaoling , Zhang Junmin , Zhao Quanyi , Ding Li , Wu Zhengrong , Jia Zhong , He Dian 
Published: August 2023

Abstract
With the continuous development of the pharmaceutical industry, people have always paid attention to the safety and effectiveness of drugs, including innovative drugs and generic drugs. For pharmaceutical companies as manufacturers, drug development is a very lengthy process that requires high costs, millions of man-hours, thousands of trials, and the mobilization of hundreds of researchers. Therefore, efforts need to be made to develop drugs with high safety and effectiveness. Drug research and development plays an important role today. Based on this, this article applied computer molecular simulation embedded technology and artificial intelligence technology to drug research and development. First, the problems faced in the research and development of anti-inflammatory disease-dependent tumor drugs were introduced, and then the applications of computer molecular simulation embedded technology and artificial intelligence technology in drug research and development were analyzed. Subsequently, the application of artificial intelligence in drug research and development teaching was analyzed, and a teaching system based on computer molecular simulation embedded technology and artificial intelligence was designed. Finally, the application effects of computer molecular simulation embedded technology and artificial intelligence technology were analyzed, and a feasible conclusion was drawn. The use of computer molecular simulation embedded technology and artificial intelligence technology can greatly improve the efficiency of drug research and development, and the research and development safety of imatinib mesylate has been improved by 7%. On the other hand, it can improve students’ learning interest and stimulate their learning interest, and students’ drug research and development capabilities have been improved. Drug research and development for inflammatory-dependent tumors has good application prospects.
Improving protection of compensated transmission line using IoT enabled adaptive auto reclosing scheme
Authors: Konda Deepthi , Patel Ujjaval , Rathi Ronak , Shah Jaynil , Chothani Nilesh 
Published: August 2023

Abstract
Protection of critical components in the power sector especially the transmission line system is very important to minimize loss of revenue, resources, and productivity. Improvement of power transfer capacity and voltage profile in smart the power grid is achieved by Series Compensation (SC). However, it poses many serious issues in the protection of compensated transmission lines. The majority of faults occurring in transmission lines are transient in nature for which service continuity can be regained by an auto-reclosing scheme. An efficient auto-reclosing scheme that can provide adaptive protection with reliable operation is required to prevent transient and permanent faults in the series compensated transmission line (SCTL). This work highlights the emulation of an Internet of Things (IoT) aided adaptive auto-reclosing scheme in association with an ESP32 controller that provides adaptive dead time control. The reclosing instance has been identified by means of a synchro-check relay. A real-time IoT-aided auto-reclosing scheme has been realized using the ESP32 controller that can generate a trip/reclosing signal instantaneously using the concepts of edge computing. The projected system has been also corroborated by simulating the modeled smart power grid network with wide variations in fault context in PSCAD. The validation of the set of rules is done in MATLAB software for the proposed auto-reclosing scheme. The extracted test outcomes of the simulation and its laboratory hardware implementation indicate an appreciable reduction in dead time which reflects the efficacy of the developed protection scheme.
Determination of a gravimetric geoid model for Eastern Province in the Kingdom of Saudi Arabia
Authors: Al Shehri Ali , Mogren Saad , Ibrahim Elkhedr , Zaki Ahmed 
Published: August 2023

AbstractA high-resolution gravimetric geoid model was developed for the Eastern Province Kingdom of Saudi Arabia region. The model was created using various datasets, including 320,434 land gravity measurements, 5442 shipborne marine gravity data, the DTU17 altimetry gravity model, and the XGM2019e global geopotential model. The computation strategy employed for modeling the gravimetric geoid involved the Remove-Compute-Restore method with Residual Terrain Model reduction and the 1D-Fast Fourier Transform approach technique. Geoid heights were determined using the Stokes integral with the Wong-Gore modification. To assess the accuracy of the resulting geoid models, they were compared with 4401 GNSS/Levelling points. The geoid accuracy throughout the entire area is better than 1.6 cm in terms of standard deviation (STD) after fitting.
Crystal structure of 2-amino-4-(2-fluoro-4-(trifluoromethyl)phenyl)-9-methoxy-1,4,5,6-tetrahydrobenzo[h]quinazolin-3-ium chloride, C20H18ClF4N3O
Authors: Li Wen-Xuan , Meng Qing-Guo , Hou Gui-Ge , Liu Yong-Jun , Zhang Meng 
Published: August 2023

Abstract
C20H18ClF4N3O, monoclinic, P21/c (no. 14), a = 9.6123(7) Å, b = 11.8692(7) Å, c = 16.9510(12) Å, β = 104.798(7)∘, V = 1869.8(2) Å3, Z = 4, Rgt
(F) = 0.0444, wRref
(F
2) = 0.1043, T = 293 K.
The marketplace landscape in Santok in the 8th–9th century, NW Poland
Authors: Zamelska-Monczak Kinga , Piotrowski Andrzej , Sydor Paweł 
Published: August 2023

Abstract
The results of archaeological research carried out on the early medieval stronghold in Santok prove that from the 2nd half of the 8th century it functioned in the contact zone between Baltic trade centres and inland, as one of the points in the network of goods exchange. We present the centre in a broader context, not only from the perspective of discovered artefacts but from the natural and ideological elements of the landscape of this place created by the communities inhabiting the Warta and Noteć valleys in the 8th and 9th centuries. The settlement was founded in a convergence of waterways in a way that perfectly uses elements of the topography of the area. Wetlands were important ecological niches for residents whose lifestyle was associated with exploring both the valley and upland zones. Santok is difficult to interpret merely as a mere reflection of the practicality of power or economic activity, including manufacturing and trade. It is a clearly legible place in the landscape, with a symbolic structure that represents the concepts of the cosmological order related to the spatial organization of the exchange point and the communication node. So far Santok is the only recognized trading post on a waterway, in this part of the Slavic region, with such an early chronology. Thus we have attempted to present the landscape of this place, considering its many elements, at different levels of perception and in a broad context.