bluuebunny/crossref_metadata_2025_split huggingface dataset:
Smart waste management perspective of COVID-19 healthy personal protective materials in concrete for decorative landscape pavements and artificial rocks
Authors: El Aal Ahmed Abd , Alsaiari Mabkhoot A. , Radwan Ahmed E. , Fenais Amr 
Published: February 2023

AbstractThis paper presents a new method for determining the effect of healthy personal protective material (HPPM) stripes, such as surgical masks, protective suits, and overhead and foot covers, on the durability and physicomechanical characteristics of concrete for use in architectural forms. Because of the current global epidemic caused by coronavirus (COVID-19), the use of HPPM, such as surgical masks, protective suits, and overhead and foot covers, has increased considerably. COVID-19’s second and third waves are currently affecting various countries, necessitating the use of facemasks (FM). Consequently, millions of single FM have been discharged into the wild, washing up on beaches, floating beneath the seas, and ending up in hazardous locations. The effect of stripe fibers on the physicomechanical characteristics of concrete, such as the workability, Uniaxial Compressive Strength UCS, flexural strength, impact strength, spalling resistance, abrasion resistance, sorptivity, Water absorption Sw, porosity (ηe), water penetration, permeability, and economic and eco-friendly aspects, need to be determined. With a focus on HPPM, especially single-use facemasks, this study investigated an innovative way to incorporate pandemic waste into concrete structures. Scanning electron microscope and X-ray diffraction patterns were employed to analyze the microstructures and interfacial transition zones and to identify the elemental composition. The HPPM had a pore-blocking effect, which reduced the permeability and capillary porosity. Additionally, the best concentrations of HPPM, particularly of masks, were applied by volume at 0, 1, 1.5, 2.0, and 2.5%. The use of mixed fibers from different HPPMs increased the strength and overall performance of concrete samples. The tendency of growing strength began to disappear at approximately 2%. The results of this investigation showed that the stripe content had no effect on the compressive strength. However, the stripe is critical for determining the flexural strength of concrete. The UCS increased steadily between 1 and 1.5% before falling marginally at 2.5%, which indicates that incorporating HPPM into concrete had a significant impact on the UCS of the mixture. The addition of HPPM to the mixtures considerably modified the failure mode of concrete from brittle to ductile. Water absorption in hardened concrete is reduced when HPPM stripes and fibers were added separately in low-volume fractions to the concrete mixture. The concrete containing 2% HPPM fibers had the lowest water absorption and porosity percentage. The HPPM fibers were found to act as bridges across cracks, enhancing the transfer capability of the matrices. From a technological and environmental standpoint, this study found that using HPPM fibers in the production of concrete is viable.
Contribution of Retzius-sparing robot-assisted radical prostatectomy to the mechanism of urinary continence as demonstrated by dynamic MRI
Authors: Kadono Yoshifumi , Nohara Takahiro , Kawaguchi Shohei , Naito Renato , Kadomoto Suguru , Iwamoto Hiroaki , Yaegashi Hiroshi , Shigehara Kazuyoshi , Izumi Kouji , Yoshida Kotaro , Gabata Toshifumi , Mizokami Atsushi 
Published: February 2023

AbstractRetzius-sparing robot-assisted radical prostatectomy (RARP) has been reported to exhibit better postoperative urinary continence, but the reasons behind this are unknown. This study included 254 cases who underwent RARP and underwent postoperative dynamic MRI. We measured the urine loss ratio (ULR) immediately after postoperative urethral catheter removal and investigated its affecting factors and the mechanisms. Nerve-sparing (NS) techniques was performed in 175 (69%) unilateral and 34 (13%) bilateral cases, whereas Retzius-sparing in 58 (23%) cases. The median ULR early after indwelling catheter removal in all patients was 4.0%. The multivariate analysis was performed on factors that reduce ULR and found that the following factors were associated with ULR: younger age, NS and Retzius-sparing, which were significant. Additionally, dynamic MRI findings showed that membranous urethral length and the anterior rectal wall movement toward the pubic bone during abdominal pressure were significant factors. The movement observed on the dynamic MRI during abdominal pressure was thought to reflect an effective urethral sphincter closure mechanism. Long membranous urethral length and an effective urethral sphincter closure mechanism during abdominal pressure were considered effective for favorable urinary continence after RARP. NS and Retzius-sparing were clearly shown to have an additive effect in preventing urinary incontinence.
Exploring the mechanism of anti-fatigue of resveratrol based on network pharmacology and molecular docking, and in vitro studies
Authors: Ma Peipei , Li Jinlei , Huang Qing , Wei Shijie , Ge Hurong , Wang Zhizhong 
Published: February 2023

AbstractTo investigate the potential mechanism of resveratrol in anti-fatigue by network pharmacology and molecular docking, and to investigate the anti-fatigue efficacy of resveratrol through in vitro animal experiments. Resveratrol action targets and fatigue-related targets were obtained using various databases. The anti-fatigue targets of resveratrol were obtained using the Venn diagram, uploaded to the String database, imported into Cytoscape 3.7.1, and constructed into a Protein-protein interaction network. The target genes were then subjected to Gene ontology and Kyoto encyclopedia of gene and genome enrichment analysis. Molecular docking verification was performed on the binding ability of the core target to resveratrol. Using swimming-trained mice as exercise models, exhaustive swimming time and fatigue-related biochemical parameters were used as indicators to investigate the effects of resveratrol on exercise endurance and energy metabolism. 104 anti-fatigue targets and 10 core target genes of resveratrol were obtained. KEGG analysis enrichment included AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, and Pathways in cancer. Molecular docking showed that the core target genes TP53, PIK3R1, AKT1, PIK3CA, and MAPK1 had good binding activity to resveratrol. Animal experiments showed that resveratrol could prolong the exhaustive swimming time of endurance-trained mice (P < 0.01), decrease aspartate aminotransferase, alanine aminotransferase, uric acid, blood lactate (P < 0.01), decrease blood urea nitrogen (P < 0.05), increase the liver glycogen, muscle glycogen (P < 0.01). Conclusion: Resveratrol has the characteristics of multiple targets and multiple pathways in anti-fatigue; resveratrol can enhance exercise endurance in mice.
Phase-change materials based on amorphous equichalcogenides
Authors: Golovchak Roman , Plummer Jarres , Kovalskiy Andriy , Holovchak Yuriy , Ignatova Tetyana , Trofe Anthony , Mahlovanyi Bohdan , Cebulski Jozef , Krzeminski Piotr , Shpotyuk Yaroslav , Boussard-Pledel Catherine , Bureau Bruno 
Published: February 2023

AbstractPhase-change materials, demonstrating a rapid switching between two distinct states with a sharp contrast in electrical, optical or magnetic properties, are vital for modern photonic and electronic devices. To date, this effect is observed in chalcogenide compounds based on Se, Te or both, and most recently in stoichiometric Sb2S3 composition. Yet, to achieve best integrability into modern photonics and electronics, the mixed S/Se/Te phase change medium is needed, which would allow a wide tuning range for such important physical properties as vitreous phase stability, radiation and photo-sensitivity, optical gap, electrical and thermal conductivity, non-linear optical effects, as well as the possibility of structural modification at nanoscale. In this work, a thermally-induced high-to-low resistivity switching below 200 °C is demonstrated in Sb-rich equichalcogenides (containing S, Se and Te in equal proportions). The nanoscale mechanism is associated with interchange between tetrahedral and octahedral coordination of Ge and Sb atoms, substitution of Te in the nearest Ge environment by S or Se, and Sb–Ge/Sb bonds formation upon further annealing. The material can be integrated into chalcogenide-based multifunctional platforms, neuromorphic computational systems, photonic devices and sensors.
Low-cost fully additively manufactured passive microwave components exploiting available 3D flexibility
Authors: Piekarz Ilona , Wincza Krzysztof , Gruszczynski Slawomir , Sorocki Jakub 
Published: February 2023

AbstractThis paper presents a novel technique for low-cost realization of fully additively manufactured passive microwave components through Stereolithography and selective metallization. The introduction of the third dimension (Z-axis) allows to improve parameters of the circuits (impedance match, isolation, etc.) by realization of variable thickness air layers underneath the circuits’ patterns, which additionally lower the overall circuit losses caused by 3D printing material dielectric properties. Realization of a directional coupler, a low-pass filter, and a patch antenna utilizing the proposed manufacturing technique is discussed in detail and experimentally validated. The obtained measurement results for circuit demonstrators operating within the centimeter frequency range prove the benefits and performance of the introduced technique.
Asian-Australian summer monsoons linkage to ENSO strengthened by global warming
Authors: Xu Chenxi , Wang S.-Y. Simon , Borhara Krishna , Buckley Brendan , Tan Ning , Zhao Yaru , An Wenling , Sano Masaki , Nakatsuka Takeshi , Guo Zhengtang 
Published: February 2023

AbstractThe El Niño-Southern Oscillation (ENSO) used to affect the Asian summer monsoon (ASM) and Australian summer monsoon (AusSM) precipitation in different ways but global warming may have changed it. This study built robust annual ASM (AusSM) precipitation reconstructions during 1588–2013 (1588–1999) to examine the ENSO-monsoon relationship and how it has changed. During the period of 1588–1850 when natural climate variability was dominant, the ENSO-monsoon and inter-monsoon relationship was weak and non-stationary. Since 1850, however, both the inter-monsoon and ENSO-monsoon relationships saw an enhancement and this trend has been persistent to the present day, suggesting the influence of anthropogenic climate warming. Further analysis of climate model projections found that global warming can strengthen the ENSO-monsoon association that, subsequently, acts to synchronize the ASM and AusSM variations.
Targeting ACE2-BRD4 crosstalk in colorectal cancer and the deregulation of DNA repair and apoptosis
Authors: Zhang Shilan , Kapoor Sabeeta , Tripathi Chakrapani , Perez Jorge Tovar , Mohan Nivedhitha , Dashwood Wan Mohaiza , Zhang Ke , Rajendran Praveen , Dashwood Roderick 
Published: February 2023

AbstractACE2 overexpression in colorectal cancer patients might increase susceptibility to SARS-CoV-2 infection. We report that knockdown, forced overexpression, and pharmacologic inhibition in human colon cancer cells targeted ACE2-BRD4 crosstalk to mediate marked changes in DNA damage/repair and apoptosis. In colorectal cancer patients for whom high ACE2 plus high BRD4 expression is predictive of poor survival, pan-BET inhibition would need to consider proviral/antiviral actions of different BET proteins during SARS-CoV-2 infection.
Unraveling topoisomerase IA gate dynamics in presence of PPEF and its preclinical evaluation against multidrug-resistant pathogens
Authors: Maurya Vikas , Singh Raja , Singh Reman Kumar , Pandey Stuti , Yadav Pooja , Parashar Palak , Gaind Rajni , Dubey Kshatresh Dutta , Naresh Patwari G. , Tandon Vibha 
Published: February 2023

AbstractType IA topoisomerases maintain DNA topology by cleaving ssDNA and relaxing negative supercoils. The inhibition of its activity in bacteria prevents the relaxation of negative supercoils, which in turn impedes DNA metabolic processes leading to cell death. Using this hypothesis, two bisbenzimidazoles, PPEF and BPVF are synthesized, selectively inhibiting bacterial TopoIA and TopoIII. PPEF stabilizes the topoisomerase and topoisomerase-ssDNA complex, acts as an interfacial inhibitor. PPEF display high efficacy against ~455 multi-drug resistant gram positive and negative bacteria. To understand molecular mechanism of inhibition of TopoIA and PPEF, accelerated MD simulation is carried out, and results suggested that PPEF binds, stabilizes the closed conformation of TopoIA with –6Kcal/mol binding energy and destabilizes the binding of ssDNA. The TopoIA gate dynamics model can be used as a tool to screen TopoIA inhibitors as therapeutic candidates. PPEF and BPVF cause cellular filamentation and DNA fragmentation leading to bacterial cell death. PPEF and BPVF show potent efficacy against systemic and neutropenic mouse models harboring E. coli, VRSA, and MRSA infection without cellular toxicity.
A heterophil/lymphocyte-selected population reveals the phosphatase PTPRJ is associated with immune defense in chickens
Authors: Wang Jie , Zhang Jin , Wang Qiao , Zhang Qi , Thiam Mamadou , Zhu Bo , Ying Fan , Elsharkawy Mohamed Shafey , Zheng Maiqing , Wen Jie , Li Qinghe , Zhao Guiping 
Published: February 2023

AbstractQuantification of leukocyte profiles is among the simplest measures of animal immune function. However, the relationship between H/L ratio and innate immunity and the measure’s utility as an index for heterophil function remains to be analyzed. Variants associated with H/L ratio were fine-mapped based on the resequencing of 249 chickens of different generations and an F2 segregating population generated by crossing selection and control lines. H/L ratio in the selection line was associated with a selective sweep of mutations in protein tyrosine phosphatase, receptor type J (PTPRJ), which affects proliferation and differentiation of heterophils through its downstream regulatory genes. The SNP downstream of PTPRJ (rs736799474) have a universal effect on H/L, with CC homozygotes exhibiting improved heterophil function because of downregulated PTPRJ expression. In short, we systematically elucidated the genetic basis of the change in heterophil function resulting from H/L selection by identifying the regulatory gene (PTPRJ) and causative SNP.
Spatial transcriptomics analysis of zone-dependent hepatic ischemia-reperfusion injury murine model
Authors: Xin Jiaqi , Yang Ting , Wu Xiaoyi , Wu Yingting , Liu Yi , Liu Xuan , Jiang Mengxi , Gao Wei 
Published: February 2023

AbstractHepatic ischemia-reperfusion (I/R) injury is a common complication in liver transplantation. The connection between I/R-induced injury response and liver heterogeneity has yet to be fully understood. In this study, we converge histopathological examination with spatial transcriptomics to dissect I/R injury patterns and their associated molecular changes, which reveal that the pericentral zones are most sensitive to I/R injury in terms of histology, transcriptomic changes, and cell type dynamics. Bioinformatic analysis of I/R injury-related pathways predicts that celastrol can protect against liver I/R injury by inducing ischemic pre-conditioning, which is experimentally validated. Mechanistically, celastrol likely implements its protective effect against I/R injury by activating HIF1α signaling and represents a potential strategy for resolving liver I/R.
Structural insights into ribonucleoprotein dissociation by nucleocapsid protein interacting with non-structural protein 3 in SARS-CoV-2
Authors: Ni Xincheng , Han Yinze , Zhou Renjie , Zhou Yanmei , Lei Jian 
Published: February 2023

AbstractThe coronavirus nucleocapsid (N) protein interacts with non-structural protein 3 (Nsp3) to facilitate viral RNA synthesis and stabilization. However, structural information on the N-Nsp3 complex is limited. Here, we report a 2.6 Å crystal structure of the N-terminal domain (NTD) of the N protein in complex with the ubiquitin-like domain 1 (Ubl1) of Nsp3 in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One NTD and two Ubl1s formed a stable heterotrimer. We performed mutational analysis to reveal the key residues for this interaction. We confirmed the colocalization of SARS-CoV-2 N and Nsp3 in Huh-7 cells. N-Ubl1 interaction also exists in SARS-CoV and Middle East respiratory syndrome coronavirus. We found that SARS-CoV-2 Ubl1 competes with RNA to bind N protein in a dose-dependent manner. Based on our results, we propose a model for viral ribonucleoprotein dissociation through N protein binding to Ubl1 of Nsp3.
Distorted octahedral cobalt(ii)–acylpyrazolone complex with a tunable lattice-strain structure – an efficient electrocatalyst for overall water splitting
Authors: Anensong Djadock Claudelle Sybilline , Vengatesan Singaram , Tagne Kuate Alain Charly , Ngoune Jean , Ravichandran Subbiah , Vasudevan Subramanyan 
Published: February 2023

Mononuclear cobalt(ii)–acylpyrazolone complexes and their structure–property relationship are described. The complexes exhibit high activity towards the OER and moderate activity for HER in alkaline medium.
Federated learning privacy incentives: Reverse auctions and negotiations
Authors: Lyu Hongqin , Zhang Yongxiong , Wang Chao , Long Shigong , Guo Shengnan 
Published: February 2023

AbstractThe incentive mechanism of federated learning has been a hot topic, but little research has been done on the compensation of privacy loss. To this end, this study uses the Local SGD federal learning framework and gives a theoretical analysis under the use of differential privacy protection. Based on the analysis, a multi‐attribute reverse auction model is proposed to be used for user selection as well as payment calculation for participation in federal learning. The model uses a mixture of economic and non‐economic attributes in making choices for users and is transformed into an optimisation equation to solve the user choice problem. In addition, a post‐auction negotiation model that uses the Rubinstein bargaining model as well as optimisation equations to describe the negotiation process and theoretically demonstrate the improvement of social welfare is proposed. In the experimental part, the authors find that their algorithm improves both the model accuracy and the F1‐score values relative to the comparison algorithms to varying degrees.
Energy efficient indoor localisation for narrowband internet of things
Authors: Keshta Ismail , Soni Mukesh , Bhatt Mohammed Wasim , Irshad Azeem , Rizwan Ali , Khan Shakir , Maaliw Renato R. , Soomar Arsalan Muhammad , Shabaz Mohammad 
Published: February 2023

AbstractThere are an increasing number of Narrow Band IoT devices being manufactured as the technology behind them develops quickly. The high co‐channel interference and signal attenuation seen in edge Narrow Band IoT devices make it challenging to guarantee the service quality of these devices. To maximise the data rate fairness of Narrow Band IoT devices, a multi‐dimensional indoor localisation model is devised, consisting of transmission power, data scheduling, and time slot scheduling, based on a network model that employs non‐orthogonal multiple access via a relay. Based on this network model, the optimisation goal of Narrow Band IoT device data rate ratio fairness is first established by the authors, while taking into account the Narrow Band IoT network: The multi‐dimensional indoor localisation optimisation model of equipment tends to minimize data rate, energy constraints and EH relay energy and data buffer constraints, data scheduling and time slot scheduling. As a result, each Narrow Band IoT device's data rate needs are met while the network's overall performance is optimised. We investigate the model's potential for convex optimisation and offer an algorithm for optimising the distribution of multiple resources using the KKT criterion. The current work primarily considers the NOMA Narrow Band IoT network under a single EH relay. However, the growth of Narrow Band IoT devices also leads to a rise in co‐channel interference, which impacts NOMA's performance enhancement. Through simulation, the proposed approach is successfully shown. These improvements have boosted the network's energy efficiency by 44.1%, data rate proportional fairness by 11.9%, and spectrum efficiency by 55.4%.
Junctionless nanosheet gate‐all‐around transistors fabricated on void embedded silicon on insulator substrate
Authors: Mu Zhiqiang , Zhou Hongyang , Yang Yumeng , Liu Qiang , Wei Xing , Yu Wenjie 
Published: February 2023

AbstractA novel junctionless gate‐all‐around (GAA) transistor with ultrathin nanosheet GAA channel and self‐aligned raised source/drain (RSD) is successfully designed and fabricated on void embedded silicon on insulator (VESOI) substrate through a much simpler fabrication process. Devices with as thin as 13‐nm nanosheet GAA channel thickness exhibit excellent electrical characteristics: on/off current ratio of 106 and on‐state drive current of 58 µA/µm. Although the parasitic planar channel component still exists, the device performance is decisively dominated by the GAA channel, and further boosted by the junction‐free bulk conduction mechanism and the self‐aligned RSD structure.
Optimal scheduling of prosumer's battery storage and flexible loads for distribution network support
Authors: Kelepouris Nikolaos S. , Nousdilis Angelos I. , Bouhouras Aggelos S. , Christoforidis Georgios C. 
Published: February 2023

AbstractHere, an efficient Energy Management System (EMS) for residential installations is proposed. The EMS handles on site Photovoltaic (PV) power production along with Battery Energy Storage System (BESS) and performs load shifting under a Demand Side Management (DSM) scheme that considers user comfort. The goal of the proposed methodology is the minimization of power exchange between the prosumer and the grid. In this way, the power flow across the Distribution Network (DN) is decreased, thus reducing power losses, and improving the voltage profile along the DN. Moreover, the EMS increases the self‐sufficiency of the residence. The minimization problem is solved via a metaheuristic algorithm, namely Unified Particle Swarm Optimization (UPSO) utilizing real consumption patterns for residential appliances. The latter adds complexity to the problem but offers accurate modelling of the power demand and improves the performance of the EMS scheme. The proposed EMS is locally implemented as a plug‐and‐play scheme and benefits both the prosumer and the DN under low computational burden, proving to be efficient. Simulation results for a case study verify the efficiency of the proposed EMS and the comparison with other similar methods proves its superior performance.