bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice
Authors: Varady Erika S , Ayala L Angel , Nguyen Pauline U , Scarfone Vanessa M , Karimzadeh Alborz , Zhou Cuiwen , Chen Xiyu , Greilach Scott A , Walsh Craig M , Inlay Matthew A 
Published: August 2023

AbstractHematopoietic cell transplantation (HCT) treats many blood conditions but remains underused due to complications such as graft‐versus‐host disease (GvHD). In GvHD, donor immune cells attack the patient, requiring powerful immunosuppressive drugs like glucocorticoids (GCs) to prevent death. In this study, we tested the hypothesis that donor cell conditioning with the glucocorticoid fluticasone propionate (FLU) prior to transplantation could increase hematopoietic stem cell (HSC) engraftment and reduce GvHD. Murine HSCs treated with FLU had increased HSC engraftment and reduced severity and incidence of GvHD after transplantation into allogeneic hosts. While most T cells died upon FLU treatment, donor T cells repopulated in the hosts and appeared less inflammatory and alloreactive. Regulatory T cells (Tregs) are immunomodulatory and survived FLU treatment, resulting in an increased ratio of Tregs to conventional T cells. Our results implicate an important role for Tregs in maintaining allogeneic tolerance in FLU‐treated grafts and suggest a therapeutic strategy of pre‐treating donor cells (and not the patients directly) with GCs to simultaneously enhance engraftment and reduce GvHD upon allogeneic HCT.
LEGAL STUDY ON RUISLAGH OF WAQF LAND WHICH IS AFFECTED BY THE DEVELOPMENT OF PUBLIC FACILITIES ON THE MAQASHID SHARIA PERSPECTIVE
Authors: YUMARNI ANI , MULYADI MULYADI , MARYAM SITI 
Published: August 2023

This article provides an explanation and disclosure of the implementation of the Transferring Function (ruislagh) of waqf land that is not in accordance with the laws and regulations. Looking back at the philosophical aspects of Islamic law by using the maqashid sharia perspective. The method used is a qualitative method using a normative juridical approach. This paper examines the principles, concepts of waqf law, legal provisions for management and transfer of waqf land functions. On the maqashid sharia perspective, the exchange of waqf property can be done as long as it met the benefits and basic needs are fulfilled through the choice of transferring function. Public cemeteries, public roads, the provision and expansion of educational facilities, and other forms of designation, in the context of Islamic law are seen as objects that are the main needs of the community. So that in order to fulfill basic needs and achieve maqashid sharia, the exchange of waqf property (ruislagh) can be held.
Models of dislocation glide and strengthening mechanisms in bcc complex concentrated alloys
Authors: Zhou Xinran , Wang Xinyi , Fey Lauren , He Sicong , Beyerlein Irene , Cao Penghui , Marian Jaime 
Published: August 2023

AbstractThe mechanical response of complex concentrated alloys (CCAs) deviates from that of their pure and dilute counterparts due to the introduction of a combinatorially sized chemical concentration dimension. Compositional fluctuations constantly alter the energy landscape over which dislocations move, leading to line roughness and the appearance of defects such as kinks and jogs under stress and temperature conditions where they would ordinarily not exist in pure metals and dilute alloys. The presence of such chemical defects gives rise to atomic-level mechanisms that fundamentally change how CCAs deform plastically at meso- and macroscales. In this article, we provide a review of recent advances in modeling dislocation glide processes in CCAs, including atomistic simulations of dislocation glide using molecular dynamics, kinetic Monte Carlo simulations of edge and screw dislocation motion in refractory CCAs, and phase-field models of dislocation evolution over complex energy landscapes. We also discuss pathways to develop comprehensive simulation methodologies that connect an atomic-level description of the compositional complexity of CCAs with their mesoscopic dislocation-mediated plastic response with an eye toward improved design of CCA with superior mechanical response.
Graphical abstract
Obtaining and study of physical-chemical properties of porous materials based on kaolin
Authors: Bondarieva Antonina , Tobilko Viktoriia 
Published: August 2023

The object of research is kaolin from the Hlukhovetsky deposit (Ukraine). On its basis, granulated sorbent materials were obtained with the addition of various amounts of cellulose as a pore former. After forming the samples, they were dried and fired at a temperature of 800 °C. The obtained granules with a size of 8–9 mm were modified with zero-valent iron. The physicochemical, including sorption properties of granular composites were studied. Using scanning electron microscopy (SEM) with energy dispersive X-ray spectroscopy (EDS), the morphology of the obtained samples was investigated and the presence of zero-valent iron particles on the surface and in the pores of the sorbents was confirmed. Based on desorption experiments, it was determined by chemical analysis that the Fe0 content in modified samples with increased pore former content increases from 0.01 g/g of granules for a sample containing 1% cellulose to 0.016 g/g for a carrier with 3 % pore former. The specific surface area and pore volume of the samples were determined by the method of low-temperature adsorption-desorption of nitrogen. Thus, with an increase in the content of the pore former in the ceramic mass, the specific surface of both unmodified and modified samples slightly decreases. Thus, with a cellulose content of 1 %, it is 20 m2/g and 17 m2/g, respectively. When the pore former is increased to 3%, these values are 15 m2/g and 12 m2/g. After applying a layer of zero-valent iron on porous granules, the volume of pores decreases, which is due to the formation of agglomerates of iron particles during synthesis. The study of the sorption capacity of the obtained sorbents with respect to Cr(VI) from model solutions containing a mixture of metal cations (copper, cadmium, cobalt, zinc) showed that granular materials exhibit sorption capacity for metal anions, even in the presence of cations. The amount of chromium sorption naturally increases for modified samples with an increase in the cellulose content in them. However, for model solutions that do not additionally contain metal cations, the sorption value is somewhat higher. Thus, for a sample with a 3 % pore former content, the sorption value is 0.7 mg/g and 0.9 mg/g, respectively, at an initial chromium(VI) concentration of 10 mg/g. The obtained experimental data indicate that the obtained porous granular sorbents based on kaolin can be used in the further treatment of wastewater from electroplating enterprises, which contain a mixture of pollutants in both anionic and cationic forms.
Preliminary results on microplastic pollution from agricultural soil in Vietnam: Distribution, characterization, and ecological risk assessment
Authors: Oanh Doan Thi , Thuy Duong Thi , My Nguyen Thi , Quynh Hoang Thi , Tam Luong Thanh , Thao Pham Phuong , Thao Pham Phuong , Thanh Nga Cao Thi , Thu Le Phuong , Hieu Phung Hieu Phung , Phuong Quynh Le Thi , Mai Anh Dang Thi , Thuy Bui Phuong , Nghi Duong Thanh , Cuong Bui Van 
Published: August 2023

Microplastics (MPs) have been extensively studied in aquatic systems; however, their presence in general agricultural systems and in particular, soil still needs comprehensive understanding. This study conducted a field survey at 25 sites to investigate the abundance of MPs in agricultural soil. The MPs in these soil samples were separated using sieves and filters by the density separation method with NaCl solution (d = 1.2 g/cm3). The density of MPs in agricultural soils ranged from 1,700 items/kg to 38,800 items/kg, with an average of 11,716 ±10,726 items/kg. The black-colored MPs were found to be dominant, followed by white, purple, red, and blue. The fibers represented most of the MPs' shapes observed in this research (77.9±17.4%). MPs in agricultural soil samples were tiny particles with sizes of <1,000 µm and 1,000-2,000 µm. A significant difference was observed in the concentration of MPs in locations near and far from residential areas and manufacturing facilities. The average concentration of MPs in the soils adjacent to the residential and manufacturing facilities and near the agricultural solid waste collection sites was 21,471±12,729 items/kg and 20,188±4,403 items/kg, much higher than in distant these locations at 4,418±1,573 items/kg. These results suggest that domestic, industrial, and agricultural activities could contribute to MP pollution in agricultural soil. The ecological dangers MPs pose in terrestrial and aquatic environments have drawn much attention from the scientific community. This work represented the first effort to comprehend the ecological risk of MPs on selected samples of Vietnamese agricultural soil. According to the Pollution Load Index (PLI) values, most agricultural soil samples in this study were contaminated with MPs at hazard level IV. The potential ecological risk index (PERI) values of agricultural soil samples from nearby residential, industrial, or agricultural solid waste areas indicated a higher ecological risk.
Mujer, criolla y “loca”. Autocensura y domesticación de Bertha Mason en la España franquista. Análisis de la traducción de Jane Eyre de Juan G. de Luaces (Iberia, 1943)
Authors: Ortega Sáez Marta 
Published: August 2023

Este artículo tiene como punto de partida la otredad en el personaje de Bertha Antoinetta Mason, que aparece en la novela Jane Eyre, de Charlotte Brontë (1847). Conocida como Bertha Mason, la esposa jamaicana criolla de Mr Rochester, vive durante años encerrada en el ático de Thornfield, debido al que se denomina en la novela su “trastorno mental”, uno de los elementos que contribuyen a construir dicha otredad. Además de este condicionante, en el contexto victoriano, la alteridad de Bertha Mason viene determinada por otros dos factores que asimismo le proporcionan una situación de inferioridad, subordinación y opresión: 1) su condición como mujer y 2) su mestizaje. En este estudio se analiza el tratamiento de esta otredad en la primera traducción de Jane Eyre publicada en el franquismo en España, llevada a cabo por Juan G. de Luaces en 1943. Por otra parte, se examina si ha existido (auto)censura en esta versión un siglo después de la publicación del texto inglés, en un contexto de involución hacia modelos ideológicos decimonónicos. Con este propósito se estudia, en primer lugar, el expediente de censura de la traducción; después, se indaga en los agentes involucrados en esta versión y se tienen en cuenta los criterios de censura de la época enumerados por Abellán; también se analizan los contextos de partida y llegada y, finalmente, se lleva a cabo un análisis microtextual para determinar los cambios encontrados en la traducción al español.
Urban environmental pollution in external and internal environments by PM2.5 particulate matter and the sick building syndrome: an overview
Authors: Da Silva Civeira Matheus , Dalmora Adilson Celimar , Do Nascimento de Campos Samuel , Gaspar Hernández Palma Hugo 
Published: August 2023

Abstract
A healthy environment must have air free of pollution, but this issue has always existed and now affects the entire population. The PM2.5 particulate matter, which primarily originates from the car fleet, is one of the pollutants that has the biggest impact. With the energy crisis in the 1970s and the ensuing construction of closed buildings (without natural ventilation), primarily in developed countries, indoor air quality emerged as a science. It then gained importance when it was found that the declining ventilation levels in those nations were largely to blame for the rising concentrations of pollutants in indoor air. The occupants of buildings themselves make a considerable contribution to the pollution of these settings through their activities, and it is well acknowledged that poor ventilation is one of the most critical factors affecting indoor air quality. Sick building syndrome and poor indoor air quality are both connected to ailments like colds, allergies, and coughing. The application of special legislation must be integrated with research and education of building occupants to effectively provide a healthy environment. The goal of this review is to analyze various findings from investigations on the effects of PM2.5 particulate matter pollution on the internal and exterior urban environment, as well as the effects of these concentrations on human health. By comparing the findings with other studies, it is possible to compare the findings and identify some common behaviors of fine particles, determining the concentration differences in the environments and showing how different sources and conditions can produce different variations in concentrations.
Prevalencia y factores asociados al desarrollo de COVID severo
Authors: Fernández Collahuazo Cristina Nataly , Guevara Pacheco Sergio Vicente , Encalada Torres Lorena Esperanza 
Published: August 2023

Introducción: la enfermedad por coronavirus SARS-CoV2 (COVID-19) de letalidad variable y amplia propagación a nivel mundial, presenta cuadros severos asociados con edad y sexo; y comorbilidades como: hipertensión arterial, enfermedades cardiovasculares, diabetes, enfermedad renal crónica y obesidad.
Objetivo: establecer la prevalencia y factores asociados a COVID severo en pacientes ingresados en el Hospital Vicente Corral Moscoso (HVCM).
Metodología: estudio transversal analítico de pacientes atendidos en el servicio de medicina interna; las variables analizadas fueron edad, sexo, diagnóstico COVID-19, comorbilidades: hipertensión arterial (HTA), enfermedades cardio vasculares (ECV), diabetes, enfermedad renal crónica (ERC), obesidad, COVID severo; se realizó estadística descriptiva con porcentajes y frecuencias, medidas de dispersión y tendencia central; se determinó asociación con el estadístico chi cuadrado y para establecer el sentido e intensidad de relación el OR en conjunto con sus intervalos de confianza. El procesamiento de la información se lo realizó en el programa estadístico SPSS 25 y se consideró una significancia del 5% (p<0.05).
Resultados: de 1 472 atendidos, presentaron COVID-19 (28.87%), 216 hombres (51%) y 209 (49%) mujeres. De los 425 con COVID-19 fueron diagnosticados de formas severas 52.2%; entre las comorbilidades que se asociaron a gravedad se encuentran: hipertensión arterial 65.69% (p<0.01; OR 2.26 IC 95% 1.48-3.45), enfermedad renal crónica 76.47% (p<0.01; OR 3.09 IC 95% 0.99-9.65) y obesidad 69.79% (p<0.01; OR 2.59 IC 95% 1.59-4.21).
Conclusiones: la prevalencia de COVID-19 fue 28.87%, el 52.2% presentó complicaciones en el HVCM siendo más frecuente en el sexo masculino y adultos mayores. El ser adulto mayor y padecer comorbilidades como hipertensión arterial, enfermedad renal crónica y obesidad son factores de riesgo relacionados a severidad.
Nasoangiofibroma juvenil: reporte de caso
Authors: Deleg Guartán Ruth Carolina , Siguencia Siguencia Angélica Gabriela 
Published: August 2023

Introducción: el nasoangiofibroma juvenil (NAFJ) es una neoplasia vasculotumoral agresiva, de histología benigna, con preferencia por el sexo masculino, en edades prepúberes y púberes. En el tratamiento quirúrgico la anestesia es un desafío al compartir campo operatorio con el cirujano con el alto riesgo de sangrado, así como morbi-mortalidad por la hemorragia que genera y por la destrucción local secundaria a su patrón de crecimiento.
Caso clínico: varón de 13 años de edad con diagnóstico de NAFJ, con epistaxis recurrente, ronquido y obstrucción nasal que empeora progresivamente, al examen físico se observa tumoración nasal izquierda, en el laboratorio reportó hemoglobina de 5,1 g/dl; se decide cirugía de emergencia (resección tumoral vía osteotomía tipo Le Fort 1). Previamente se transfundieron concentrados globulares, hemodinámicamente estable. Como anestesiología se procedió a realizar un buen manejo de la vía aérea conjuntamente con el cirujano se exterioriza el TET a través de una disección submentoniana (secuencia de Altemir), un adecuado monitoreo hemodinámico, manejo de líquidos guiado por metas, autotransfusión autóloga mediante el uso del cell saver optimizando y disminuyendo el riesgo de sangrado, y monitorizando la necesidad de transfusión de hemoderivados dirigida e individualizada mediante el uso del tromboelastograma transoperatorio. Terminado procedimiento quirúrgico fue trasladado a la Unidad de Cuidados Intensivos Pediátricos (UCIP), con evolución favorable fue dado de alta y mejoría significativa en controles por consulta externa.
Conclusiones: el abordaje de un paciente con NAFJ es un desafío para el anestesiólogo, previo a la cirugía se transfundieron concentrados globulares, se realizó abordaje anestésico con intubación orotraqueal, durante el acto quirúrgico se emplearon medidas para optimizar y disminuir el sangrado con antifibrinolíticos, hipotensores y cell saver, paciente evoluciona favorablemente.
QUALIDADE DE VIDA DE PESSOAS COM FERIDAS CRÔNICAS E A ATUAÇÃO DO ENFERMEIRO
Authors: Brito Kyonayra Quezia Duarte , Leal Almeida Layze Amanda 
Published: August 2023

Objetivo: descrever as características da produção científica em enfermagem acerca da qualidade de vida dos indivíduos com feridas crônicas no Brasil. Método: trata-se de um estudo descritivo com abordagem quantitativa, do tipo revisão bibliométrica. A coleta de dados foi realizada entre dezembro de 2020 e março de 2021, por meio de consulta na Biblioteca Virtual em Saúde (BVS). Os termos utilizados, de forma simultânea, para a busca foram “Feridas Crônicas” e “Qualidade de Vida”. Resultados: sete artigos apresentavam os critérios de inclusão e foram eleitos para compor a amostra. Esse estudo apontou algumas lacunas na produção de enfermagem acerca da temática escolhida, relacionadas à quantidade de estudos, abordagem metodológica e tamanho da amostra. Uma dificuldade verificada foi a diversidade de instrumentos utilizados para aferir a qualidade de vida. A dor esteve relacionada à baixa qualidade de vida. Conclusão: o plano terapêutico de enfermagem deve considerar a integralidade do paciente.
Descritores: Qualidade de vida; Feridas; Assistência de enfermagem.
Results of a Systematic Intensive Follow-Up of 259 Cases of Obstetric Anal Sphincter Injury
Authors: Fons Laura Blanch , Roda Oriol Porta , Peró Marta , Roca Paula Fabra , González Marta Simó 
Published: August 2023

BACKGROUND:Obstetric anal sphincter injury (OASI) is a complication of childbirth. Some women will develop symptoms, which may appear in the short or long term. In most clinical practice guidelines, follow-up is only recommended in women with anal incontinence (AI). In our hospital, follow-up is offered to all women who suffer an OASI: Anorectal manometry (ARM) and endoanal ultrasound (EAUS) are scheduled for all patients. The aim of this study was to determine if a symptom-based or systematic follow-up was better for these patients. To do so, we compared the results of investigations (EAUS and ARM) between asymptomatic and symptomatic women.METHODS:A retrospective analysis of prospectively collected data from 259 women who suffered an OASI in a single tertiary hospital in Barcelona (Spain) between May 2008 and May 2018.RESULTS:Seventy-seven percent of women attended the first follow-up visit at the perineal clinic, and 40.5% of women completed the 12-month follow-up. At initial evaluation, 60% of the patients had a Wexner score of 0. Seventy-two percent of women had an abnormal result on one or both investigations (EAUS and ARM).CONCLUSIONS:Attendance and adherence to our follow-up protocol are low. Although the incidence of AI symptoms is low at early follow-up in women after OASI, they show a high rate of functional dysfunctions on manometry. If follow-up is offered only to symptomatic patients, it could lead to an underestimation of their true condition.
DESAFIOS VIVENCIADOS POR DOCENTES NO ENSINO DE ENFERMAGEM DURANTE O CONTEXTO DA PANDEMIA COVID-19: Revisão Integrativa da Literatura
Authors: Macena Mateus Santos , Vecchi Marjorye Polinati da Silva 
Published: August 2023

Em decorrência da interrupção das aulas presenciais frente a emergência sanitária da COVID-19, as tecnologias digitais se tornaram fortes aliados para garantir a comunicação entre professor e aluno. Frente esse cenário, as atividades pedagógicas foram garantidas por meio da modalidade de ensino remoto, no qual os docentes do ensino de enfermagem vivenciaram desafios relacionados a adaptação do currículo a essa modalidade de ensino. O objetivo do estudo foi identificar os desafios enfrentados por docentes na educação em enfermagem no contexto da pandemia COVID-19. Trata-se de uma revisão integrativa da literatura baseado em um protocolo de pesquisa validado e as recomendações Statement for Reporting Systematic and Meta-Analyses of Studies (PRISMA). As informações obtidas com os estudos analisados foram organizadas em três grandes categorias, sendo: desafios relacionados ao processo ensino-aprendizagem, à infraestrutura e a atividade profissional versus cotidiano familiar. Os resultados contribuem para a prática pedagógica baseada em evidência de enfermeiros docentes, possibilitando reflexões para estratégias que garantem a qualidade no ensino de enfermagem durante contextos pandêmicos e fortalecendo a tomada de decisões do processo de trabalho desses profissionais.
EFFECT OF ANXIETY AND WORK FATIGUE ON JOB BURNOUT, DISTRESS, HEALTH EATING INDEX AND BLOOD PRESSURE THROUGH COPING MECHANISM IN OIL AND GAS COMPANY
Authors: Arini Shintia Yunita , Atmaka Dominikus Raditya , Nurhakim Irpan , Shodiq Andian , Roshida Devy Syanindita 
Published: August 2023

Introduction: Workers in oil and gas companies are one of several groups of workers who have a heavy workload, both physically and psychologically, owing to the heavy work responsibilities related to the duration of work, which is not in accordance with the standard working time specified in Indonesia. Based on research conducted in similar industries, 69% of workers in critical jobs experience both acute and chronic fatigue. If not managed properly, it will result in occupational burnout. Aims: of this research was to determine whether there is a relationship between coping style, eating habits, work stress, fatigue and occupational burnout Method: Design study of cross-sectional manner with the research respondents being permanent workers in oil and gas companies in Bojonegoro, East Java. The total sample comprised of 102 respondents. The data obtained will then be statistically processed using IBM SPSS software with multiple regression tests. Result: The level of work fatigue experienced by oil and gas company employees had a significant indirect effect on the healthy eating index through the copying mechanism variable, and the anxiety experienced by oil and gas company employees had a significant indirect effect on the healthy eating index and blood pressure, both systolic and systole, and diastole via the copying mechanism variable. Conclusion: Anxiety experienced by workers influences the healthy eating index and systolic blood pressure with coping mechanisms as an intervening variable. Work fatigue experienced by workers influences the healthy eating index, with coping mechanisms as an intervening variable.