bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crisis communication in the WHO COVID-19 press conferences: A retrospective analysis
Authors: He Sike , Li Dapeng , Liu Chang-Hai , Xiong Ying , Liu Dan , Feng Jiaming , Wen Ju 
Published: March 2023

ObjectivesThe objective of this study is to investigate, from a longitudinal perspective, how WHO communicated COVID-19 related information to the public through its press conferences during the first two years of the pandemic.MethodsThe transcripts of 195 WHO COVID-19 press conferences held between January 22, 2020 and February 23, 2022 were collected. All transcripts were syntactically parsed to extract highly frequent noun chunks that were potential topics of the press conferences. First-order autoregression models were fit to identify “hot” and “cold” topics. In addition, sentiments and emotions expressed in the transcripts were analyzed using lexicon-based sentiment/emotion analyses. Mann-Kendall tests were performed to capture the possible trends of sentiments and emotions over time.ResultsFirst, eleven “hot” topics were identified. These topics were pertinent to anti-pandemic measures, disease surveillance and development, and vaccine-related issues. Second, no significant trend was captured in sentiments. Last, significant downward trends were found in anticipation, surprise, anger, disgust, and fear. However, no significant trends were found in joy, trust, and sadness.ConclusionsThis retrospective study provided new empirical evidence on how WHO communicated issues pertaining to COVID-19 to the general public through its press conferences. With the help of the study, members of the general public, health organizations, and other stake-holders will be able to better understand the way in which WHO has responded to various critical events during the first two years of the pandemic.
Relationship between fall history and toe grip strength in older adults with knee osteoarthritis in Japan: A cross-sectional study
Authors: Mawarikado Yuya , Inagaki Yusuke , Fujii Tadashi , Kubo Takanari , Kido Akira , Tanaka Yasuhito 
Published: March 2023

Background
Knee osteoarthritis (KOA), one of the most common musculoskeletal diseases in older adults, is associated with a high incidence of falls. Similarly, toe grip strength (TGS) is associated with a history of falls in older adults; however, the relationship between TGS and falls in older adults with KOA who are at risk of falling is not known. Therefore, this study aimed to determine if TGS is associated with a history of falls in older adults with KOA.

Methods
The study participants, older adults with KOA scheduled to undergo unilateral total knee arthroplasty (TKA), were divided into two groups: non-fall (n = 256) and fall groups (n = 74). Descriptive data, fall-related assessments, modified Fall Efficacy Scale (mFES), radiographic data, pain, and physical function including TGS were evaluated. The assessment was conducted on the day before performing TKA. Mann–Whitney and chi-squared tests were performed to compare the two groups. Multiple logistic regression analysis was performed to determine the association of each outcome with the presence or absence of falls.

Results
Mann-Whitney U test revealed that the fall group had statistically significantly lower height, TGS on the affected and unaffected sides, and mFES. Multiple logistic regression analysis revealed that the incidence of fall history is associated with TGS on the affected side; the weaker the affected TGS of the KOA, the more likely the individual is to fall.

Conclusions
Our results indicate that TGS on the affected side is related to a history of falls in older adults with KOA. The significance of evaluating TGS among patients with KOA in routine clinical practice was demonstrated.
IMPACT OF METEOROLOGICAL FACTORS ON THE PROPAGATION OF COVID-19 IN JOHOR
Authors: Vallasamy Suriya Kumareswaran 
Published: March 2023

Introduction
The global distribution and severity of COVID-19 have been markedly heterogeneous. Seasonality has been indicated as a contribution to regional variability, although the relationship between weather and COVID-19 is still unclear, and outside environments have been the focus of investigation. Even though laboratory and epidemiological research have proven the impact of ambient temperature on the transmission and survival of coronaviruses, nothing is known about the weather's impact on the spread of COVID-19.
Objectives
This study investigates the effects and association of temperature, humidity, precipitation, wind speed on the rising of COVID-19 cases in Johor, Malaysia
Methodology
From January 2021 to December 2022, daily COVID-19 case data was gathered from the COVIDNOW Malaysian website dedicated to covid-19, while satellite climate data for the same period was taken from the official website of the National Aeronautics and Space Administration (NASA). A descriptive analysis was undertaken to characterise all the important variables across the study period. Correlation analysis was conducted to investigate the linear relationship between covid-19 cases and climate factors.
Results
The result shows there is positive correlation between COVID-19 cases towards rainfall and temperature (p value <0.01). Also, the results show there is no correlation between COVID-19 cases towards windspeed and humidity.
Conclusion
The results indicate that climate characteristics are useful for minimising the uncertainty surrounding the severity of future COVID-19 transmission. These correlations between climate conditions and covid-19 cases can be used to generate early warning for any future epidemic, allowing for the adoption of stringent regulations, the preparation of healthcare service plans, and the targeting of vaccination coverage.
Autoimmune Enteropathy: A Rare Cause of Chronic Diarrhea in an Adult Patient
Authors: Carvalho Ana C. , Pinho Juliana , Cancela Eugénia , Silva Américo 
Published: March 2023

ABSTRACT
Autoimmune enteropathy is a rare cause of malabsorption usually associated with circulating autoantibodies and predisposition to autoimmune disorders. The diagnosis is based on the following criteria: chronic diarrhea (>6 months), malabsorption, specific histological findings, anti-enterocyte and anti-goblet cell antibodies, and exclusion of similar disorders. We report a case of a 73-year-old woman presenting with severe chronic diarrhea, weight loss, and electrolyte abnormalities. Endoscopy revealed duodenal villous atrophy extending to proximal jejunum, and duodenal biopsies revealed villous blunting, cryptitis with apoptosis, and scattered intraepithelial lymphocytes. Therapeutic management included immunosuppressive treatment with corticosteroids, achieving clinical remission.
Effect of Stream River and Tidal on the Suspended Sediment Concentration of Kuala Langsa Estuary, Aceh, Indonesia
Authors: Irwansyah Irwansyah , Isma Faiz , Ismida Yulina , Isma Muhammad Fauzan , Sufahani Suliadi Firdaus , Akbar Helmy 
Published: March 2023

Kuala Langsa estuary is a semi-closed zone where there is an exchange of two water masses between river and tidal of the Malacca Strait. The exchange of those two water masses occurs as a physical result of fluctuating estuaries. This caused Suspended Sediment Concentration (SSC) continue to increase as the estuary is the final distribution point for sediment brought from upstream by erosion in the Langsa River. This sediment contributes to the silting of Langsa estuary. This is caused the KRI dr. Soeharso Hospital to be unable to dock at the Kuala Langsa Port during the 66th Surya Bhaskara Jaya Navy Operations 2017. It’s necessary to study estuary physical conditions, which include bathymetry, currents, temperature, salinity, and concentrations of floating sediment that occur as a result of the tides and river discharges. This research used quantitative and qualitative exploratory methods, analyzed a direct correlation between the measurement results, roughness coeficient, and sediment transport rate used relevant empirical equations (Duboy's, Einstein's, Rottner, Chang, Simons, and Richardson, and Lane and Kalinske aquations). This research found that the Langsa estuary is 16 km with a semidiurnal tidal type. In the Langsa estuary, it was discovered that the highest sediment rate was at the mouth of the estuary is 10.700.739,71 ton/day-1 and the physical model of Muara Langsa has a good correlation to the results of measurements-model indicate value of CC width = 0.959 and tide CC= 0.421, This study provides initial information for conducting hydrodynamic and morphological models at the mouth of estuary.
New record of Halymenia malaysiana (Halymeniaceae, Rhodophyta) from Viet Nam, and its genetic diversity in the western Pacific
Authors: Nguyen Xuan-Vy , Nguyen-Nhat Nhu-Thuy , Nguyen Xuan-Thuy , Nguyen Trung-Hieu , Truong Si Hai Trinh , Dao Viet-Ha , Do Anh-Duy , McDermid Karla J. 
Published: March 2023

Abstract

Halymenia malaysiana, one of the foliose species of Halymenia was first reported from Malaysia and showed some morphological features that distinguish it from sister species, such as Halymenia dilatata, Halymenia maculata, and Halymenia porphyraeformis. In this study, Halymenia samples were collected from nine locations along the coast of Viet Nam (8°–17°N) in the South China Sea and Gulf of Thailand. Morphological observations indicated that almost all samples were Halymenia malaysiana which was supported by two genetic markers, rbcL and COI-5P. However, the presence of Halymenia dilatata in Viet Nam is still unresolved. Based on rbcL, the common haplotype in Viet Nam was R1 as in Malaysia and three new haplotypes were added to H. malaysiana for Southeast Asia. Genetic differences were evident between the Sunda Shelf (Viet Nam and Malaysia) populations and those in Philippine waters. We suggest that a combination of morphology and molecular data would be useful to accurately assess the species diversity and phylogeography of Halymenia in Viet Nam and Southeast Asia region.
A semiotic-discursive insight into short videos on memory and peace
Authors: Pardo Abril Neyla Graciela 
Published: March 2023

Abstract
This paper explores how short web videos uploaded to the Truth Commission’s TikTok official profile are formulated. The Truth Commission (Comisión de la Verdad) is a Colombian state entity created to clarify patterns and causes of Colombia’s internal armed conflict and recognize victims’ and society’s right to the truth. The Commission’s aim is to avoid repetition of violence through an ample and plural participation process to construct a stable and lasting peace. To explore the debate and the importance of recognizing crimes against humanity committed in the context of the armed conflict in Colombia – specifically, sexual violations against ethnically and territorially defined women – two videos were selected under thematic, territorial, ethnic, and gender-unity criteria from among 60 short videos published on TikTok between February 2020 and March 2021. The nuclear axis of the videos corresponds to the semiotic theory at the core of the multimodal and multimedia critical discourse analysis (MMCDA). The digital discourse is multimodal, as its design, production, and distribution process draws from various and coexisting sign systems: visual-graphic (image-color), visual-verbal-graphic, verbal-sound, and sound-musical. These devices are proposed as “memory devices” that allow viewers to witness human rights violation events in the context of Colombia’s current armed conflict.
Interaction of RTX toxins with the host cell plasma membrane
Authors: Chacko Feby M. , Schmitt Lutz 
Published: March 2023

Abstract

Repeats in ToXins (RTX) protein family is a group of exoproteins secreted by Type 1 secretion system (T1SS) of several Gram-negative bacteria. The term RTX is derived from the characteristic nonapeptide sequence (GGxGxDxUx) present at the C-terminus of the protein. This RTX domain binds to calcium ions in the extracellular medium after being secreted out of the bacterial cells, and this facilitates folding of the entire protein. The secreted protein then binds to the host cell membrane and forms pores via a complex pathway, which eventually leads to the cell lysis. In this review, we summarize two different pathways in which RTX toxins interact with host cell membrane and discuss the possible reasons for specific and unspecific activity of RTX toxins to different types of host cells.
The High Frequency Firm Survey “Bundesbank Online Panel – Firms”
Authors: Boddin Dominik , Köhler Mona 
Published: March 2023

Abstract
The Bundesbank Online Panel – Firms (“BOP-F”) is a dataset with responses from a high frequency firm-level survey of the same name. The Bundesbank has conducted the survey since June 2020, and since July 2021 the survey has been carried out at a monthly frequency. Every month, around 3000 firms from all economic sectors, regions and size classes are surveyed. The survey consists of recurring core questions about the economic situation of firms and their expectations and special questions that usually differ from quarter to quarter. The latter often relate to current topics, for instance, climate change, digitalization, Covid-19. The data can be accessed for research and especially the possibility to combine it with other administrative Bundesbank data makes it particularly valuable for research. The objective of this paper is to describe the methodology of the data collection, the content data as well as the data’s research potential.
Enhanced heat resistance and expansion ratio of biodegradable poly (lactic acid)/poly (butylene adipate-co-terephthalate) composite foams via synergistic effect of nucleating agent and chain extension
Authors: Huang Feng , Liu Wei , Lai Jun , Wu Jianming , Huang An , Geng Lihong , Peng Xiangfang 
Published: March 2023

Abstract
Environmentally friendly foams have been studied extensively to handle the plastic pollution caused by disposable tableware. Herein, biodegradable poly (lactic acid) (PLA) – poly (butylene adipate-co-terephthalate) (PBAT) composites were first fabricated by melt blending, in which a reactive chain extender (ADR) was incorporated to enhance the interfacial compatibility and melt strength, a nucleating agent (TMC) was applied to improve the crystallinity. Subsequently, the foaming behavior of the composites was investigated via supercritical CO2 foaming. Specifically, a spherulite and shish-kebab-like nanoporous structure was observed from PLA and PLA/TMC foams, respectively, when the soaking temperature was far below melting temperature. With an increase of foaming temperature, the unmelted completely crystals served as physical cross-linking points, also contributing to a high melt strength. Combined with chain extension reaction of ADR, the PLA–PBAT/ADR/TMC foams showed the largest cell diameter and expansion ratio, which were 19 μm and 8.9, respectively. Furthermore, the heat resistance of PLA–PBAT/ADR/TMC foams was also significantly improved, owing to the high crystallinity induced by TMC. Consequently, the composite foams with superior heat resistance and toughness were obtained to broaden its application as biodegradable disposable tableware for hot food.
On testing for bubbles during hyperinflations
Authors: Morita Rubens , Psaradakis Zacharias , Sola Martin , Yunis Patricio 
Published: March 2023

Abstract
We consider testing for the presence of rational bubbles during hyperinflations via an analysis of the non-stationarity properties of relevant observable time series. The test procedure is based on a Markov regime-switching model with independent stochastic changes in its intercept, error variance and autoregressive coefficients. This model formulation allow us to disentangle fundamentals-driven changes in the drift, bubble-driven explosiveness, and volatility changes that may be fundamentals-driven and/or bubble-driven. The testing methodology is illustrated by applying it to data from hyperinflations in Argentina, Brazil, Germany and Poland.
Crystal structure of three chloridocuprate(I, II) complexes with methylene blue (MB) counterions
Authors: Sabirov Vahobjon Kh. , Kadirova Mukarram X. 
Published: March 2023

Abstract
Three chloridocuprate complexes with methylene blue counterions of the chemical compositions [MB]+
2[CuCl4]2− · H2O (1), [MB]+
2[CuCl4]2− (2) and [(MB)+(CuCl2)−]3 (3) (where [MB]+ – methylthioninium cation; methylene blue cation) have been prepared by solvent-assisted mechanochemical synthesis. The reactions were carried out by mixing the copper(II) chloride dihydrate, CuCl2⋅2H2O, and methylene blue pentahydrate, [MB]+Cl− · 5H2O by grinding in an agate mortar with the addition of DMF as a solvent. The crystal structures of the compounds have been determined by single-crystal X-ray diffraction. The content of an asymmetric unit of the crystals consists of: (1) a tetrahedral [CuCl4]2− anion, two [MB]+ cations and one water molecule of crystallization; (2) a tetrahedral [CuCl4]2− anion and two [MB]+ cations; (3) trimeric [(MB)+(CuCl2)−]3 molecules with the Cu atoms coordinated by a nitrogen atom of the phenothiazine ring and two chlorine ions in a trigonal planar geometry with the copper atom in the oxidation state of +1.
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
Authors: Salvadó Gemma , Ossenkoppele Rik , Ashton Nicholas J , Beach Thomas G , Serrano Geidy E , Reiman Eric M , Zetterberg Henrik , Mattsson‐Carlgren Niklas , Janelidze Shorena , Blennow Kaj , Hansson Oskar 
Published: March 2023

AbstractSeveral promising plasma biomarkers for Alzheimer's disease have been recently developed, but their neuropathological correlates have not yet been fully determined. To investigate and compare independent associations between multiple plasma biomarkers (p‐tau181, p‐tau217, p‐tau231, Aβ42/40, GFAP, and NfL) and neuropathologic measures of amyloid and tau, we included 105 participants from the Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) with antemortem plasma samples and a postmortem neuropathological exam, 48 of whom had longitudinal p‐tau217 and p‐tau181. When simultaneously including plaque and tangle loads, the Aβ42/40 ratio and p‐tau231 were only associated with plaques (ρAβ42/40[95%CI] = −0.53[−0.65, −0.35], ρp‐tau231[95%CI] = 0.28[0.10, 0.43]), GFAP was only associated with tangles (ρGFAP[95%CI] = 0.39[0.17, 0.57]), and p‐tau217 and p‐tau181 were associated with both plaques (ρp‐tau217[95%CI] = 0.40[0.21, 0.56], ρp‐tau181[95%CI] = 0.36[0.15, 0.50]) and tangles (ρp‐tau217[95%CI] = 0.52[0.34, 0.66]; ρp‐tau181[95%CI] = 0.36[0.17, 0.52]). A model combining p‐tau217 and the Aβ42/40 ratio showed the highest accuracy for predicting the presence of Alzheimer's disease neuropathological change (ADNC, AUC[95%CI] = 0.89[0.82, 0.96]) and plaque load (R2 = 0.55), while p‐tau217 alone was optimal for predicting tangle load (R2 = 0.45). Our results suggest that high‐performing assays of plasma p‐tau217 and Aβ42/40 might be an optimal combination to assess Alzheimer's‐related pathology in vivo.
Age-standardized incidence, mortality rate, and trend changes of thyroid cancer in the Balearic Islands during the 2000–2020 period: a population-based study
Authors: Tofé Santiago , Argüelles Iñaki , Forteza Ana , Álvarez Cristina , Repetto Alessandra , Masmiquel Luis , Rodríguez Irene , Losada Eladio , Sukunza Nuria , Cabrer María , Sifontes Mildred , del Mar del Barrio María , Barceló Antonia , Tofé Álvaro , Pereg Vicente 
Published: March 2023

Objective
Global thyroid cancer (TC) incidence is growing worldwide, but great heterogenicity exists among published studies, and thus, population-specific epidemiological studies are needed to adequate health resources and evaluate the impact of overdiagnosis.

Methods
We conducted a Public Health System database retrospective review of TC incident cases from 2000 to 2020 in the Balearic Islands region and evaluated age-standardized incidence rate (ASIR), age at diagnosis, gender distribution, tumor size and histological subtype, mortality rate (MR), and cause of death. Estimated annual percent changes (EAPCs) were also evaluated and data from the 2000–2009 period were compared to the 2010–2020 period when neck ultrasound (US) was routinely performed by clinicians at Endocrinology Departments.

Results
A total of 1387 incident cases of TC were detected. Overall, ASIR (×105) was 5.01 with a 7.82% increment in EAPC. A significant increase in the 2010–2020 period was seen for ASIR (6.99 vs 2.82, P < 0.001) and age at diagnosis (52.11 vs 47.32, P < 0.001) compared to the 2000–2009 period. A reduction in tumor size (2.00 vs 2.78 cm, P < 0.001) and a 6.31% increase in micropapillary TC (P < 0.05) were also seen. Disease-specific MR remained stable at 0.21 (×105). The mean age at diagnosis for all mortality groups was older than survivors (P < 0.001).

Conclusion
The incidence of TC has grown in the 2000–2020 period in the Balearic Islands, but MR has not changed. Beyond other factors, a significant contribution of overdiagnosis to this increased incidence is likely due to changes in the routine management of thyroid nodular disease and increased availability of neck US.
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility
Authors: Zhang Ying , Bruna de Lima Camila , Labrecque Rémi , Sirard Marc-André 
Published: March 2023

In brief
Bull fertility is an important economic trait, this study identified some DNA methylation biomarkers that are associated with bull fertility.

Abstract
Subfertile bulls may cause huge economic losses in dairy production since their semen could be used to inseminate thousands of cows by artificial insemination. This study adopted whole-genome enzymatic methyl sequencing and aimed to identify candidate DNA methylation markers in bovine sperm that correlate with bull fertility. Twelve bulls were selected (high bull fertility = 6; low bull fertility = 6) based on the industry’s internally used Bull Fertility Index. After sequencing, a total of 450 CpG had a DNA methylation difference higher than 20% (q < 0.01) had been screened. The 16 most significant differentially methylated regions (DMRs) were identified using a 10% methylation difference cut-off (q < 5.88 × 10−16). Interestingly, most of the differentially methylated cytosines (DMCs) and DMRs were distributed on the X and Y chromosomes, demonstrating that the sex chromosomes play essential roles in bull fertility. Additionally, the functional classification showed that the beta-defensin family, zinc finger protein family, and olfactory and taste receptors could be clustered. Moreover, the enriched G protein-coupled receptors such as neurotransmitter receptors, taste receptors, olfactory receptors, and ion channels indicated that the acrosome reaction and capacitation processes are pivotal for bull fertility. In conclusion, this study identified the sperm-derived bull fertility-associated DMRs and DMCs at the whole genome level, which could complement and integrate into the existing genetic evaluation methods, increasing our decisive capacity to select good bulls and explain bull fertility better in the future.