bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the operator learning curve for radiofrequency ablation for atrioventricular nodal reentrant tachycardia
Authors: Küp Ayhan , Celik Mehmet , Kepez Alper , Demir Serdar , Gulsen Kamil , Ozgeyik Mehmet , Kanar Batur Gonenc , Karagoz Ali , Yildirim Cagan , Tanircan Muhammmed Rasit , Akgun Taylan , Uslu Abdulkadir 
Published: June 2023

Aim The aim of this study was to determine the average minimum number of slow pathway ablation procedures required to reach a steady success rate among inexperienced operators.Material and Methods We analyzed the consecutive AVNRT ablation procedures of three inexperienced operators for the rate of operational success and complications.Results Operators performed a total of 156 AVNRT ablation procedures. There was no statistical significance between the three operators regarding the rate of success (p=0.69) and complications. There were significant differences between the operators in terms of procedure time, fluoroscopy time, and cumulative air kerma. The variability of procedure time and cumulative air kerma, both among three operators and within each operator, decreased significantly after the 25th case. Each operator was analyzed individually for the probability of success as related to the cumulative number of ablations. All trainee operators reached a success rate of 90 % at the 27th procedure.Conclusion An average of 27 slow pathway ablation procedures should be performed by a beginner operator to achieve proficiency.
ANALYSIS OF MAXILLARY FRACTURE PATIENTS PROFILE IN A TERTIARY GENERAL HOSPITAL (2018-2020)
Authors: Suarta I Dewa Gde Daniswara , Agus Santoso Budi  , Rosy Setiawati  , Magda Rosalina Hutagalung  
Published: June 2023

Highlights:

Maxillary fractures predominantly affected adult males aged between 18 and 64, comprising 92.36% of the cases studied.
The most common type of maxillary fracture observed was Le Fort 3, followed by other Le Fort classes.
The preferred treatment method for maxillary fractures was ORIF mini plating, which resulted in favorable outcomes with minimal complications.

Abstract:
Introduction: The maxilla is a crucial bone in the midface, playing a significant role both functionally and cosmetically. Analyzing the medical records of maxillary fractures at Dr. Soetomo General Academic Hospital would offer an overview of the various treatments used and their corresponding outcomes were the aim of this study. This data would provide a general understanding of the patient’s conditions during maxillary fracture treatment and could potentially support further research in this field.
Methods: In this study, data on the profile, treatment, and management of maxillary fractures were taken from patient medical records at Dr. Soetomo General Academic Hospital between 2018 and 2020.
Result: The study examined 144 cases of maxillary fractures at Dr. Soetomo General Academic Hospital, analyzing medical records and surgery reports from 2018 to 2020. Most of the patients (92.36%) were adult males (78.47%) aged between 18 and 64. The most common type of maxillary fracture observed was Le Fort 3 (47.22%), while other Le Fort classes accounted for fewer cases. The preferred treatment method was ORIF mini plating (81.25%), and the average hospital stay was around 12.56 days. Only one patient experienced post-treatment malocclusion in the 144 cases. In terms of complications, there were minimal instances of infections and exposed plates, with a total of four cases reported.
Conclusion: The treatment outcomes at Dr. Soetomo General Academic Hospital showed lower incidence rates of post-surgical issues like malocclusion, infections, and exposed plates when compared to other current datasets.
Effects of pea-tea intercropping on rhizosphere soil microbial communities
Authors: Song Laichao , Niu Zhanhai , Chen Shiliang , Zhao Shilei , Qiu Ziyuan , Wang Yu , Hua Xuewen , Ding Zhaotang , Ma Qingping 
Published: June 2023

Abstract
Background and Aim
Pea-tea intercropping is known to improve tea quality but its potential mechanism remains unclear. This study aimed to elucidate the effects of pea-tea intercropping on rhizosphere soil microbial communities and interpret its potential role in the improvement of tea quality.
Methods
A high-throughput sequencing method was used to detect the microbial communities in the rhizosphere of pea-intercropped tea plants. KEGG and eggNOG databases were used for the functional annotation of microbial DNA sequences. Carbohydrate-active enzymes were used to evaluate soil quality.
Results
Some microbes in the rhizosphere of pea-intercropped tea plants showed large variations, particularly phyla Acidobacteria and Proteobacteria. The abundance of Bradyrhizobiaceae of Proteobacteria, which help in nitrogen fixation, increased significantly. The annotation of carbohydrate-active enzymes revealed that the relative content of glycoside hydrolases (GHs) increased significantly in the soil microbes of pea-intercropped tea plants. The KEGG analysis showed that more amino acid- and carbohydrate metabolism-related genes were enriched in the soil microbes of pea-intercropped tea plants. To sum up, pea-tea intercropping could improve tea quality by regulating soil microbes in terms of carbon- and nitrogen-fixing capacities.
Comparatory Evaluation of the Ecotoxic Effects of Flavour and Fragrance Aldehydes, Ketones, Oximes, and Oxime Ethers
Authors: Balcerzak Lucyna , Trusz Agnieszka , Piekarska Katarzyna , Strub Daniel J. 
Published: June 2023

Abstract
Due to their toxicity, some aroma chemicals are banned by national, regional, and international regulatory bodies. As a result, the development of novel fragrance compounds is in line with the goals of several industrial sectors, including household chemistry, cosmetics, and fragrance. In this study, we examine the effects of new potential fragrances of the oxime ether class on bacteria (Alivibrio fischeri), microalgae (Raphidocelis subcapitata), plants (Spirodela polyrhiza) and crustaceans (Daphnia magna). We assessed a total of 24 substances including commercially relevant flavors and fragrances such as perillartine, buccoxime, stemone or citral oxime, and compared the oxime ethers' and oximes toxicity to that of the parent carbonyl compounds. The toxicity of the oxime ethers ranged from non-acute (class I), low-acute (class II), acute (class III), high-acute (class IV), and very high-acute toxicity (V). In most cases, the toxicity of oxime ethers was similar to or lower than the toxicity of commercially exploited flavours and fragrances. The most sensitive organisms were A. fischeri and S. polyrhiza, and all of the compounds showed very high acute toxicity toward it.
Status of oral health screening of diabetes patients: A questionnaire study
Authors: Akter Salma , Alam Mohammad Kamrul 
Published: June 2023

Abstract
Background:
Oral complications are prevalent in diabetes and these complications have potential impact on patients’ overall health and well-being. The aim of the study was to investigate the frequency of oral health screenings among patients with diabetes and its associated factors.
Methods:
A cross sectional study was conducted involving 106 patients. Data were collected with a pretested and structured questionnaire. Chi-square test was conducted to assess the association between outcome variables and selected covariates. At the same time, multivariate binary logistics regression model was used to determine the factors that are related to oral health screening status of diabetes patients. SPSS (Statistical Package for Social Science) version 25 was used for data management, analysis.
Results:
Of the respondents, only 28.30 percent of the diabetes patients in the study had received an oral health screening. Participants having higher educational level were more likely to have oral health screening than those who cannot read and write (OR = 1.733). Moreover, the odds of having an oral health check-up were less likely who had higher monthly income compared to those who had monthly salary less than 15000 taka (OR = 0.163 and 0.115 respectively). The odds of people who brush their teeth two or more times a day were more likely to have oral screening against those who brush their teeth once a day (OR = 0.202). Participants who knew diabetes affect the teeth were three times higher to have oral screening than their counterparts (OR = 3.250) whereas those who knew oral check-up prevents tooth loss were more prone to go for oral screening than their counterparts.
Conclusion:
The findings of the study indicate that there is a need to improve the oral health screening status among diabetes patients in the country. The factors identified as associated with a higher frequency of oral health screening- higher educational level, lower monthly income, higher frequency of tooth brushing per day can help inform targeted interventions to improve screening rates. To improve oral health screening for diabetes patients, health education programs can be implemented to increase awareness and understanding of the importance of regular dental check-ups.
Development of a PPP1R14B-associated immune prognostic model for hepatocellular carcinoma
Authors: Zhao Ligang , Chen Zhangjun , Lei Zhengqing , Yu Zeqian , Wang Lishan , Zhou Jiahua 
Published: June 2023

Abstract
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. Immunotherapy has been widely reported to have sustained and strong antitumor effects in a variety of tumors with active immune microenvironments, including HCC. PPP1R14B not only involves in the initiation of cancers, but also affects tumor progression and prognosis. However, the roles of PPP1R14B and the associations with immune microenvironment in HCC have not been investigated. RNA-seq and clinical data of HCC was acquired from TCGA database. We mainly focused on the roles of PPP1R14B and the associations with the immune microenvironment in HCC. The results showed that PPP1R14B was significantly increased in HCC samples compared with the control group, and its high expression was significantly correlated with survival outcome, immune status, and response to immunotherapy. We also observed a significant correlation between PPP1R14B expression and chemotherapy drug sensitivity. In addition, we established an immune prognostic model associated with ppp1r14b, which has high predictive power for the prognosis of HCC patients. This study contributes to stratify HCC patients into sub-populations to develop personalized treatment strategy.
Non-invasive neurally-adjusted ventilatory assist in preterm infants with respiratory distress: a systematic review and meta-analysis
Authors: Minamitani Yohei , Miyahara Naoyuki , Saito Kana , Kanai Masayo , Namba Fumihiko , Ota Erika 
Published: June 2023

Abstract
Non-invasive neurally-adjusted ventilatory assist (NIV-NAVA) improves patient-ventilator synchrony and reduces treatment failure in preterm infants compared with nasal continuous positive airway pressure (NCPAP) and non-invasive positive-pressure ventilation (NIPPV). We conducted a systematic review and meta-analysis to assess the effectiveness of NIV-NAVA in preterm infants with respiratory distress. Four investigators independently assessed the eligibility of studies in CENTRAL, CINAHL, ClinicalTrials.gov, Embase, MEDLINE, PubMed, and WHO ICTRP databases, and extracted data. The included studies were randomized controlled trials (RCTs) comparing NIV-NAVA with other non-invasive ventilation modalities in preterm infants. The certainty of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach and four RCTs which examined 259 preterm infants were eligible to this study. In the subgroup of secondary use after extubation, NIV-NAVA reduces the risk of treatment failure compared with NCPAP/NIPPV (risk ratio 0.29; 95% confidence interval [0.10, 0.81], 2 RCTs, 96 infants, low certainty of the evidence). In the subgroup of primary use at birth, no statistically significant differences in treatment failure were observed (very low certainty of the evidence). Moreover, there were no significant differences in secondary outcomes. Therefore, NIV-NAVA may prevent treatment failure and the requirement of reintubation in preterm infants.
A study of the required sustainability-driven institutional and behavioural mechanisms to tackle the anticipated implications of agricultural water price shocks: A system dynamics approach
Authors: Momeni Marzieh , Razavi Vahid , Zahedi Sina , Momeni Farshad , Behzadian Kourosh , Dolatabadi Neda 
Published: June 2023

Abstract
Economic policies for managing agricultural water use are often complicated by the challenge of using water prices as an efficient economic tool when other non-economic concerns are involved in the decision-making process. This study aims to analyse the impact of water pricing policies on preserving agricultural water resources in Iran. This study applies a system dynamics approach to simulate the system performance and behaviour of stakeholders and the economic implications. Our finding shows that water pricing policies will likely fail due to low water price elasticity and if there are lack of institutional and physical infrastructure, alternative professions, manufacturing technology, education, and training opportunities. The results also illustrate how agricultural water price increase (AWPI) fails to reduce water consumption in the absence of an adequate institutional arrangement. Also, it shows how the lack of advanced institutional infrastructure in the presence of physical infrastructure enhances pervasive overuse and destructive competition among stakeholders by increasing the area under cultivation. In the discussion, the paper portrays a way out to the decision-making body by following AWPI effects on water conservation in the agricultural sector as the most significant water consumer. It investigates the absence and subsequent presence of specific institutional conditions and evaluates training and enhancing farmers' skills and alternative career sources with better income and technology as the architecture of good environmental governance. Finally, it concludes that a series of inclusive measures must be considered to increase the elasticity of the water price. These measures must stimulate farmers towards pursuing the goals of global sustainable development and enhancing social welfare.
Risk factors of postoperative hypoalbuminemia in patients undergoing radical surgery for ovarian cancer
Authors: Yang Zhuo-xuan , Chen Ying-yin , Zhou Shu-zhi 
Published: June 2023

Abstract
Objective
This study aimed to explore the perioperative risk factors for postoperative hypoalbuminemia in patients undergoing radical surgery for ovarian cancer.
Methods
Clinical data of 142 patients who underwent radical surgery for ovarian cancer at Ya'an People's Hospital from January 2017 to June 2022 were retrospectively analyzed. According to the albumin levels on the day of surgery, the patients were divided into a study group (serum albumin < 35g/L) and a control group (serum albumin ≥ 35g/L). The preoperative, intraoperative and postoperative data of the two groups were compared, and the perioperative risk factors for hypoalbuminemia in patients undergoing radical surgery for ovarian cancer were analyzed by univariate and multivariate binary logistic regression analysis.
Results
Of 142 patients, 69 (48.59%) developed hypoalbuminemia after surgery. Univariate analysis showed that increased intraoperative fluid volume, high intraoperative blood loss, substantial preoperative ascites volume, open surgery, concomitant gastrointestinal surgery, and long surgery time were related to the occurrence of hypoalbuminemia after surgery, and the difference was statistically significant (P < 0.05). Multivariate binary logistic regression analysis indicated that low preoperative albumin level, high CRP, large amount of ascites, and concomitant gastrointestinal surgery were independent risk factors for hypoalbuminemia in ovarian cancer patients after surgery (P < 0.05). Additionally, patients in the study group had higher rates of postoperative complications, longer hospital stays, and higher ICU admission rates.
Conclusion
The incidence of postoperative hypoalbuminemia is high in ovarian cancer patients. Low preoperative albumin level, high CRP, large amount of ascites, and concomitant gastrointestinal surgery are independent risk factors for postoperative hypoalbuminemia in patients undergoing radical surgery for ovarian cancer, which can have an adverse impact on clinical outcomes.
Pressure ulcer and low-temperature burn development in an elderly patient following prolonged surgery with forced-air warming system: A case report
Authors: Lee Soo Jee , Choi Beomseok , Suh Jaewoo , Ki Seunghee 
Published: June 2023

Abstract
Background
The forced-air warming system has been commonly used to prevent hypothermia during surgery and anesthesia. Traditionally, forced-air warming blankets have been not only used to cover and warm up the patient but also placed under the patient to secure sufficient skin to warm up. However, many clinicians are oblivious to how the novel method of using a warming blanket affects a patient’s skin and often lack the knowledge and awareness needed for the appropriate use of forced-air warming systems.
Case presentation
: A 79-year-old man presented to the hospital for robotic proctectomy under general anesthesia. The forced-air warming system was used to prevent intraoperative hypothermia, with the forced-air warming blanket placed under the patient. The surgery lasted for 7 h, and the forced-air warming devices were continuously used for 5 h intraoperatively. The surgery was completed without any incidents. However, a low-temperature burn on the patient’s back along with a localized pressure ulcer on his right scapula was observed.
Conclusions
It should be noted that forced-air warming systems can cause skin complications. To minimize complications, they must be used correctly, and appropriate preventive methods should be considered. Fundamentally, the patient’s skin should be continuously monitored intraoperatively.
Can a Nomogram Predict the Failure Risk of Internal Fixation Devices in Chinese Patients Undergoing Hip Arthroplasty?
Authors: Huang Chumin , Li Feilong , zeng Zisan 
Published: June 2023

Abstract
Background:In order to achieve more accurate and personalized patient risk assessments and further understand the superposition effect of multiple risk factors, it is imperative to develop and validate a nomogram for the risk of failure of hip arthroplasty in Chinese patients.
Methods:Data from 1198 patients who underwent hip arthroplasty in the First Affiliated Hospital of Guangxi Medical University from February 2012 to January 2021 were collected. Then, 1014 cases were assigned to the normal group and 184 cases to the failure group. Patients were further divided into training and verification tests. The risk assessment of failure for hip arthroplasty comprised 18 variables. In the training test, LASSO regression was applied to optimize the characteristics of revision hip arthroplasty. Lastly, significant variables in the LASSO regression analysis were included in the multivariate logistic regression analysis.
Results:The C index was 0.715 (95% confidence interval: 0.667-0.763), and the area under the curve (AUC) was 0.715. Decision curve analysis illustrated that the predictive value of the nomogram was high, and its net income was between 0.06 and 0.4 or 0.51 to 0.69. Moreover, the C index of the validation test was 0.680. The parameters in the risk nomogram included body mass index (BMI), collar or collarless femoral stem, sparse trabecular bone, presence or absence of screws and the number of screws, history of diabetes, and occupation.
Conclusion: The model had a satisfactory predictive ability. The higher the score, the higher the probability of failure. This will aid doctors in assessing the risk of failure of patients undergoing hip arthroplasty prior to the intervention.
Does Eating Fish Cause Cancer? A Case Study Metal Accumulation in Mackerel and Sardine Tissues from Iskenderun Bay, Türkiye
Authors: Ergen Şeyda Fikirdeşici , Altındağ Ahmet , Baş Yavuz Selim 
Published: June 2023

Abstract
Due to the increasing harmful effects of metals(loid)s over time, it has become an important issue in environmental studies carried out to increase environmental awareness. It is important to investigate the cumulative presence of metals in nature, their interactions with each other and the risks posed by fish consumption for human health. Total concentrations of As, Cd, Cu, Fe, Mn, Ni, Pb and Zn were determined in muscle and gill tissues of sardine and horse mackerel. Fe and Zn concentrations were the highest and Cd, Cu and Pb concentrations were the lowest. Target hazard coefficient, estimated daily intake, target cancer risk, total target hazard coefficient and hazard indices were calculated to assess the risks to an individual's health from consuming fish. Hazard index and total target hazard coefficient values calculated for each fish exceeded 1 but were very close to 1. Target cancer risk values of As and Ni were found to be 10-6 and 10-4 for Pb. These limit values indicate the need for regular monitoring of the region. In addition, the interactions between the metals accumulated in the tissues were analysed and a high correlation was found between As-Ni, which poses a risk to public health.
Prioritizing Roadside Ditch Retrofitting to Improve Water Quality in a Mixed-use Watershed
Authors: Qiu Zeyuan , Testa Christopher , Obropta Christopher C. 
Published: June 2023

Abstract
Roadside ditches are one of the most common landscape features in an urbanizing landscape. Poorly maintained ditches exacerbate floods and degrade water quality. Roadside ditch retrofitting offers a unique opportunity to address both water quantity and quality issues related to stormwater. However, given the extensiveness of roadside ditches, it is challenging to determine where the retrofitting efforts should take place. The study proposed a three-step procedure to prioritize roadside ditches for retrofitting based on the hydrological sensitivity and connectiveness of a landscape and applied it to the Neshanic River watershed with mixed land uses in Central New Jersey. Specifically, we delineated the hydrologically sensitive areas (HSAs) in the watershed that have high propensity to runoff generation and accumulation, selected the ditches intersecting with HSAs for consideration of retrofitting and finally ranked the selected ditches for retrofitting with high, medium and low priority based on their physical conditions. There were 853 ditches in 40.3 km mapped in the watershed, 322 ditches in 29.7 km were intersected with HSAs. Among 322 ditches considered for retrofitting, only 125 ditches were ranked for retrofitting with high priority. The study also applied the propensity score matching method to compare the conditions of the ditches that did and didn’t intersect with HSAs and found the ditches intersecting with HSAs were more likely experiencing deterioration that those not intersecting with HSAs. The proposed procedure is very useful tool to scout and prioritize roadside ditches for maintenance and improvement when personnel, time and other resources are limited.