bluuebunny/crossref_metadata_2025_split huggingface dataset:
Point-Prevalence Survey for the Hospital-Acquired Infections and Infection Prevention and Control Status of Different Wards of Rajshahi Medical College Hospital
Authors: Haque Md Jawadul , Yasmin Farhana , Arif Md Ashfaq , Rahman Nahreen , Parven Rehana , Asaduzzaman Md , Alam Muhammad Zubayer 
Published: August 2023

Introduction: Healthcare-associated infections represent significant obstacles to providing high-quality healthcare and have been directly linked to ineffective infection control procedures. There is currently a shortage of trustworthy data in Bangladesh describing the epidemiology of hospital-acquired infections (HAIs), which is necessary for the development of effective infection prevention and control measures. This study's goal was to assess the frequency, nature, and risk factors of HAIs in acute care hospitals in Northern Bangladesh.
Methods: This was a pilot point prevalent survey conducted in the medicine, surgery, gynecology, and obstetrics departments of Rajshahi Medical College Hospital between August 2022 to September 2022. Data were collected by two questionnaires for disease profile and hospital-acquired infection. In addition, a checklist was used for the observation of the infection prevention and control (IPC) status of different wards.
Result: Approximately 900 patients' data were collected during this time period. The overall prevalence of HAI was found to be 3.7%. The prevalence of HAI, especially surgical site Infection (SSI), in the obstetrics ward, was 4.2%, and the Medicine ward was 3.9%, respectively. The prevalence of hospital-acquired infection in the surgery ward is 7.7%. Approximately 41.7% of patients developed SSI on the 6th post operative day (POD). The Infection prevention and control status of different wards was similar, which was not satisfactory.
Conclusion: This surveillance might help concerned authorities and policymakers by making some crucial steps to monitor and reduce hospital-acquired infections and HAIs in hospitals.
TAJ 2022; 36: No-1: 9-15
Prevalence of Dermatophytic Infections and Their Antifungal Susceptibility Pattern in the Rajshahi Region
Authors: Khan Md Mottalib Hossain , Haque Md Ahsanul , Kabir Farjana , Nath Shubhra Kanti Dev , Zahan Rozina Aktar , Rahman Nahreen 
Published: August 2023

Background: Dermatophytes are the most significant fungi because of their widespread involvement in the population and their prevalence worldwide. Bangladesh's hot and humid climate, overcrowded population, poverty, malnutrition, and ignorance make dermatophytosis a common cutaneous infection. These infections occur in both healthy and immunocompromised patients. Dermatophytes are responsible for most cutaneous fungal infections, and the estimated lifetime risk of acquiring a dermatophyte infection is 10-20%.
Objective: To isolate and identify different dermatophytes and their antifungal susceptibility pattern in the Rajshahi region. Materials and Methods: Different clinical samples (e.g., skin scrapings, nail clipping, and hair plucking) were collected under aseptic precautions. The isolation and identification of dermatophytes were performed through a microscopic examination using 10% KOH mount, mycological culture, and species identification by lactophenol cotton blue mount from positive culture. In addition, all dermatophytes isolates were subjected to antifungal susceptibility testing using the agar-based disk diffusion method in Mueller Hinton agar media.
Results: Out of 171 samples, Trichophyton rubrum was the predominant dermatophyte species with 76(71.7%), followed by T.mentagrophyte were 15(14.2%), E. floccosum were 12(11.3%), and M. canis were 03(2.8%). voriconazole, clotrimazole, and itraconazole were more effective drugs. Griseofulvin was the least effective drug, followed by fluconazole.
Conclusion: This study indicates dermatophytosis is a common skin disease in northern Bangladesh. Due to the increasing trend of antifungal drug resistance among dermatophytes, treatment should be based on antifungal sensitivity testing.
TAJ 2022; 36: No-1: 119-125
Pembuatan Data Warehouse secara Berjenjang dari Data Transaksi dengan ETL Script PHP
Authors: Aisyah Yuliana , Anwar Syaiful , Samidi - 
Published: August 2023

Setiap perusahaan payment gateway yang mendapat ijin operasional Bank Indonesia (BI), harus melaporkan data transaksinya setiap bulan ke BI . Permasalahan terjadi karena database transaksi produksi tersebar di banyak database, dimana database dipisahkan berdasarkan channel (merchant) dan payment type (Credit card, VA, retail store, e-wallet), hal ini menyulitkan saat pembuatan laporan. Penelitian ini ditujukan untuk membuat data warehouse yang menggabungkan seluruh database dengan menggunakan script PHP yang melakukan proses ETL (Extract, Transform, dan Load), dengan cara berjenjang 2 tahap, yaitu tahap 1 melakukan backup seluruh database dari banyak server ke satu server dengan 3 tujuan sekaligus yaitu backup transaksi , meningkatkan performance database production dan membantu proses rekonsiliasi dan tahap 2 melakukan pembuatan data warehouse dari semua database backup dari tahap 1. Penelitian yang digunakan adalah kuantitatif verifikatif terhadap table-table yang diperlukan pada system OLTP (Online Transaction Processing). Pengujian data warehouse dilakukan secara kuantitatif dengan membandingkan hasil summary dari data warehouse dengan gabungan summary semua database aslinya dan secara verifikatif oleh petugas report melalui User Acceptance Test. Hasil dari penelitian adalah sebuah script untuk backup data transaksi dari semua database dari banyak server ke satu server, sebuah script PHP yang berfungsi sebagai pelaksana ETL dan sebuah data warehouse.
Optimalisasi Fitur Pencarian Pada E-Catalog Menggunakan Query Expansion Dan Algoritma TF-IDF
Authors: Kusuma Selvia Ferdiana , Badriyah Tessy , Wibowo Prasetyo , Faradisa Rosiyah , Huda Solichul 
Published: August 2023

E-catalog adalah sebuah katalog elektronik dapat digunakan untuk mempublikasikan dan mempromosikan sebuah produk atau layanan secara online kepada berbagai pihak. Pengguna dapat memperoleh informasi terkait produk yang diinginkan melalui fitur pencarian pada e-catalog tersebut. Oleh sebab itu fitur pencarian memiliki peran yang signifikan untuk menunjang performa e-catalog. Proses pencarian produk pada sebuah e-catalog dilakukan berdasarkan kesamaan kata yang dimasukkan oleh pengguna dengan judul produk yang tersedia. Biasanya semua judul yang mengandung kata kunci yang dimasukkan pengguna akan ditampilkan tanpa adanya perankingan kedekatan hasil pencarian. Hal tersebut tentunya menyulitkan pengguna untuk menemukan produk yang sesuai dengan keinginan. Oleh sebab itu penelitian ini bertujuan untuk melakukan optimalisasi fitur pencarian produk yang ada pada e-catalog menggunakan query expansion dan algoritma TF-IDF. Berdasarkan hasil uji coba yang telah dilakukan, terbukti bahwa penambahan query expansion dan algoritma TF-IDF dapat mengoptimalkan kinerja fitur pencarian pada e-catalog tersebut. Hasil pencarian produk dapat terangking berdasarkan kedekatan kata kunci yang dimasukkan oleh pengguna dengan judul produk yang diinginkan oleh pengguna
Transcatheter aortic valve replacement with the VenusA-Pro and VenusA-Plus systems: preliminary experience in China
Authors: Li Jie , Sun Yinghao , Luo Songyuan , Zheng Shengneng , Chen Jiaohua , Fu Ming , Fang Zhenfei , Wang Yan , Li Guang , Fan Ruixin , Luo Jianfang 
Published: August 2023

BackgroundThe outcomes of transcatheter aortic valve replacement (TAVR) employing the second-generation retrievable VenusA-Pro and VenusA-Plus delivery systems with the self-expanding VenusA-Valve have not been described yet. This study aims to report the outcomes of these two second-generation delivery systems.MethodsFrom January 2022 to April 2023, we prospectively enrolled patients with severe aortic stenosis undergoing TAVR with VenusA-Pro from three centers across China in this first-in-man study and retrospectively identified those undergoing TAVR with VenusA-Plus. All outcomes were reported according to the Valve Academic Research Consortium 3 definition. The primary outcome was 30-day all-cause mortality.ResultsA total of 156 patients were included, of which 46 underwent TAVR with VenusA-Pro and 110 underwent TAVR with VenusA-Plus. The Society of Thoracic Surgeons median score was 2.1%, bicuspid anatomy prevalence rate was 55.1%, and the mean aortic root calcification volume was 693 mm3. The technical success rate was 91.7%, comparable between the VenusA-Pro and VenusA-Plus groups (87.0% vs. 93.6%, P = 0.169). The 30-day all-cause mortality was 2.6%, similar between the VenusA-Pro and VenusA-Plus groups (2.2% vs. 2.7%, P = 0.842). No myocardial infarction occurred. The incidences of stroke (0.6%), major bleeding (3.8%), major vascular complications (5.1%), acute kidney injury (9.0%), permanent pacemaker implantation (5.1%), new-onset atrial fibrillation (5.8%), and moderate-to-severe paravalvular aortic regurgitation (6.0%) were favorable and comparable between the two groups. The clinical outcomes were similar between the patients with bicuspid and tricuspid aortic valve, except that the incidence of permanent pacemaker implantation was lower in patients with bicuspid anatomy (1.2% vs. 10.6%, P = 0.010).ConclusionsThe 30-day outcomes of TAVR with VenusA-Pro and VenusA-Plus were favorable and comparable.
Complex styles of phreatomagmatic explosions at Kīlauea Volcano, Hawaii, controlled by magma structure
Authors: Schmith J. , Swanson D. A. 
Published: August 2023

Explosive eruptions at basaltic volcanoes remain poorly understood. Kīlauea Volcano is a type locality for basaltic eruptions and is well-known for effusive activity. However, more than 7 m of phreatomagmatic Keanakākoʻi Tephra unit D deposits from explosive eruptions crown the southern rim of the summit caldera and provide a stark reminder of Kīlauea’s explosive past and future potential. We used detailed field observations as well as granulometric and morphological analysis of 100 samples from two proximal sections to assess the eruption style and fragmentation mechanism. The deposits can be divided into four subunits, six different lithofacies, and contain three juvenile tephra components. Each juvenile component shows distinct shape variability resulting from molten fuel-coolant interaction (MFCI) explosions of magma of variable vesicularity. Fragmentation of dense glass generates olive-green ash, fragmentation of low to moderately vesicular magma generates a dark gray ash-lapilli component, and fragmentation of highly vesicular magma generates light-yellow pumice. Our work shows that magma structure impacts MFCI explosion efficiency. Small-scale planar bedding throughout most of the deposit points to a general eruption style of small, frequent explosions generating low plumes. Thicker beds of accretionary lapilli of fine-extremely fine ash are related to very efficient magma-water mixing. Pyroclastic density current (PDC) deposits in the upper part of the stratigraphy contain at least three flows but show no significant dune or cross-bedding structures. We suggest that this is a function of the vent being situated in a caldera that was then ∼600 m deep, where the caldera wall acted as a barrier and changed the flow dynamics to very dilute overspills and co-PDC plume falls over the wall. Deconvolution modeling of the polymodal grain size distributions is used to assess grain size changes of each juvenile component for this deposit, which greatly improves interpretation of lithofacies generation and eruption dynamics. Size-correlated shape parameters show that shape data across a wide size range are needed to accurately track grain shapes. This study demonstrates how careful examination of grain size and shape of juvenile tephra clasts can help volcanologists understand how effusive basaltic volcanoes can become violently explosive.
Influence of different rainfall patterns and soil water content on hydrological processes in small watersheds
Authors: Li Chaochao , Li Chenglu , Bao Shuping , Li Mingyang 
Published: August 2023

Introduction: Due to climate and underlying surface changes, flash floods occur frequently in northwest China, and the extreme rainstorm weather and flash floods along the eastern foot of Helan Mountain are increasing.Method: By constructing a hydrological model to simulate ten historical mountain flood events in the Suyukou watershed of the eastern foot of Helan Mountain, this study explores the constitutive relationship between rainfall and flood, evaluates accuracy, and analyzes errors. Six characteristic rain patterns were designed based on three parameters representing the position of rainfall peaks and the trend characteristics of rainfall, using 63 actual rainfall processes with a duration of 6 h selected from the rainfall stations of Suyukou watershed. Early warning indicators under different conditions were carried out based on the set of rain patterns.Results: The research results indicate that eight out of the ten simulated floods have passed the qualification test and the simulation results are good. The HEC-HMS hydrological model is suitable for simulating mountain floods in small watersheds and can provide good support for the simulation and early warning of mountain flood disasters.Discussion: Designing a rain pattern set based on actual data has put forward higher requirements for mountain flood warning and forecasting, making the warning more in line with the local actual situation and greatly improving the effectiveness of warning and forecasting.
Predictors of rapidly progressive interstitial lung disease and prognosis in Chinese patients with anti-melanoma differentiation-associated gene 5-positive dermatomyositis
Authors: Li Meiqi , Zhao Xuli , Liu Baocheng , Zhao Yaqi , Li Xinya , Ma Zhenzhen , Yang Qingrui 
Published: August 2023

BackgroundRapidly progressive interstitial lung disease (RP-ILD) is the most serious complication of anti-melanoma differentiation-associated gene 5-positive dermatomyositis (anti-MDA5+ DM). This study was performed to assess the prognostic factors of patients with anti-MDA5+ DM and the clinical characteristics and predictors of anti-MDA5+ DM in combination with RP-ILD.MethodsIn total, 73 MDA5+ DM patients were enrolled in this study from March 2017 to December 2021. They were divided into survival and non-survival subgroups and non-RP-ILD and RP-ILD subgroups.ResultsThe lactate dehydrogenase (LDH) concentration and prognostic nutritional index (PNI) were independent prognostic factors in patients with anti-MDA5+ DM: the elevated LDH was associated with increased mortality (p = 0.01), whereas the elevated PNI was associated with reduced mortality (p &lt; 0.001). The elevated LDH was independent risk prognostic factor for patients with anti-MDA5+ DM (HR 2.42, 95% CI: 1.02–4.83, p = 0.039), and the elevated PNI was independent protective prognostic factor (HR, 0.27; 95% CI, 0.08 - 0.94; p = 0.039). Patients who had anti-MDA5+ DM with RP-ILD had a significantly higher white blood cell count and LDH concentration than those without RP-ILD (p = 0.007 and p = 0.019, respectively). In contrast, PNI was significantly lower in patients with RP-ILD than those without RP-ILD (p &lt; 0.001). The white blood cell count and elevated LDH were independent and significant risk factors for RP-ILD (OR 1.54, 95% CI: 1.12 - 2.13, p = 0.009 and OR 8.68, 95% CI: 1.28 - 58.83, p = 0.027, respectively), whereas the lymphocyte was an independent protective factor (OR, 0.11; 95% CI, 0.01 - 0.81; p = 0.03).ConclusionThe elevated LDH and elevated PNI were independent prognostic factors for patients with anti-MDA5+ DM. The elevated LDH was independent risk factor for RP-ILD. Patients with anti-MDA5+ DM could benefit from the measurement of LDH and PNI, which are inexpensive and simple parameters that could be used for diagnosis as well as prediction of the extent of lung involvement and prognosis.
Emergence of Raoultella ornithinolytica in human infections from different hospitals in Ecuador with OXA-48-producing resistance
Authors: Villacís José E. , Castelán-Sánchez Hugo G. , Rojas-Vargas Jorge , Rodríguez-Cruz Ulises E. , Albán Viviana , Reyes Jorge A. , Meza-Rodríguez Pablo M. , Dávila-Ramos Sonia , Villavicencio Fernando , Galarza Margarita , Gestal Monica C. 
Published: August 2023

PurposeThe purpose of this study was to highlight the clinical and molecular features of 13 Raoultella ornithinolytica strains isolated from clinical environments in Ecuador, and to perform comparative genomics with previously published genomes of Raoultella spp. As Raoultella is primarily found in environmental, clinical settings, we focused our work on identifying mechanisms of resistance that can provide this bacterium an advantage to establish and persist in hospital environments.MethodsWe analyzed 13 strains of Raoultella ornithinolytica isolated from patients with healthcare associated infections (HAI) in three hospitals in Quito and one in Santo Domingo de Los Tsáchilas, Ecuador, between November 2017 and April 2018. These isolates were subjected to phenotypic antimicrobial susceptibility testing, end-point polymerase chain reaction (PCR) to detect the presence of carbapenemases and whole-genome sequencing.ResultsPolymerase chain reaction revealed that seven isolates were positive isolates for blaOXA–48 and one for blaKPC–2 gene. Of the seven strains that presented the blaOXA–48 gene, six harbored it on an IncFII plasmid, one was inserted into the bacterial chromosome. The blaKPC gene was detected in an IncM2/IncR plasmid. From the bioinformatics analysis, nine genomes had the gene blaOXA–48, originating from Ecuador. Moreover, all R. ornithinolytica strains contained the ORN-1 gene, which confers resistance for β-lactams, such as penicillins and cephalosporins. Comparative genome analysis of the strains showed that the pangenome of R. ornithinolytica is considered an open pangenome, with 27.77% of core genes, which could be explained by the fact that the antibiotic resistance genes in the ancestral reconstruction are relatively new, suggesting that this genome is constantly incorporating new genes.ConclusionThese results reveal the genome plasticity of R. ornithinolytica, particularly in acquiring antibiotic-resistance genes. The genomic surveillance and infectious control of these uncommon species are important since they may contribute to the burden of antimicrobial resistance and human health.
Comparison of cerebrospinal fluid space between probable normal pressure hydrocephalus and Alzheimer’s disease
Authors: Li Hongliang , Liu Chunyan , Tai Hong , Wei Youping , Shen Taizhong , Yang Qiong , Zheng Keyang , Xing Yan 
Published: August 2023

IntroductionIdiopathic normal pressure hydrocephalus (INPH) is a potentially reversible syndrome characterized by complex symptoms, difficulty in diagnosis and a lack of detailed clinical description, and it is difficult to distinguish from Alzheimer’s disease (AD). The objective of this study was to design a method for measuring the actual amount of hydrocephalus in patients with INPH and to evaluate INPH.MethodsAll subjects underwent a 3D T1-weighted MRI. Statistical parametric mapping 12 was used for preprocessing images, statistical analysis, and voxel-based morphometric gray matter (GM) volume, white matter (WM) volume, and cerebrospinal fluid (CSF) volume analysis. The demographic and clinical characteristics of the groups were compared using a t-test for continuous variables and a chi-square test for categorical variables. Pearson’s correlation analysis and Bonferroni’s statistic-corrected one-way ANOVA were used to determine the relationship among demographic variables. Receiver operating characteristic (ROC) curves were used to assess the accuracy of the callosal angle (CA), WM ratio, and CSF ratio in distinguishing probable INPH from AD.ResultsThe study included 42 patients with INPH, 32 patients with AD, and 24 healthy control subjects (HCs). There were no differences among the three groups in basic characteristics except for Mini-Mental State Examination (MMSE). There was a correlation between the intracranial CSF ratio and CA. The WM ratio and CSF ratio in patients with INPH and AD were statistically different. Furthermore, the combination of CA, WM ratio, and CSF ratio had a greater differential diagnostic value between INPH and AD patients than CA alone.ConclusionINPH can be accurately assessed by measuring intracranial CSF ratio, and the addition of WM ratio and CSF ratio significantly improved the differential diagnostic value of probable INPH from AD compared to CA alone.
Erythrocytic alpha-synuclein as potential biomarker for the differentiation between essential tremor and Parkinson’s disease
Authors: Yu Zhenwei , Liu Genliang , Zheng Yuanchu , Huang Guoshi , Feng Tao 
Published: August 2023

IntroductionThe differentiation between essential tremor (ET) and Parkinson’s disease (PD) can be difficult because of the symptom overlaps. Erythrocytes are the major source of peripheral α-synuclein (α-syn), which is the most studied pathological molecular of PD. We have reported that erythrocytic α-syn levels in PD patients are significantly increased compared to those in healthy controls (HCs). However, little is known about the levels of erythrocytic α-syn species in ET patients.MethodsThis study includes 15 patients with ET, 64 patients with PD, and 49 age and sex matched HCs. A well-established electrochemiluminescence assay was used to measure the erythrocytic total and aggregated α-syn levels. The receiver operating characteristic (ROC) curve analysis was applied to evaluate the diagnostic values of erythrocytic α-syn for ET diagnosis and differentiation. The correlations of erythrocytic α-syn levels with disease durations were tested using Spearman’s Rank Correlation analysis.ResultsWe found that both erythrocytic total and aggregated α-syn concentrations are significantly increased in PD and ET patients compared to those in HCs. Erythrocytic total α-syn levels are significantly higher in ET patients than those in PD group. Furthermore, the ratios of erythrocytic aggregated to total α-syn levels in ET patients are significantly decreased than those in PD and HC subjects. We also found a significant association of erythrocytic aggregated α-syn levels with the disease duration of ET patients.ConclusionOur findings suggest new insight into the changes of erythrocytic total and aggregated α-syn levels as potential biomarkers for ET patients.