bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prioritizing risk factors and identifying target areas to address with interventions to improve sustainable employment of persons with a brain injury or a spinal cord injury – A multi-stakeholder consensus process
Authors: Finger Monika E. , Karcz Katarzyna , Schiffmann Barbara , Eugster Julia , Selb Melissa 
Published: February 2023

BackgroundAchieving sustainable long-term employment is the goal of work integration for persons with acquired brain injury (ABI) or spinal cord injury (SCI). However, decreasing employment rates over time for persons with ABI and SCI indicate that remaining employed in the long-term is a challenge.PurposeTo identify the most important risk factors that pose a barrier to sustainable employment of persons with ABI or SCI from a multi-stakeholder perspective, and to propose corresponding interventions that address them.MethodsMulti-stakeholder consensus conference and follow-up survey.ResultsFrom 31 risk factors to sustainable employment of persons with ABI or SCI identified in previous studies, nine were defined as most important to address with interventions. These risk factors either impacted the person, the work environment or service provision. Potential interventions to address these factors were proposed in mixed condition groups, of which ten were voted on as priority interventions. The follow-up survey revealed strong agreement on the intervention proposals, strong to moderate agreement on impact, but moderate to low feasibility, as most of the interventions were measures at the meso- (service) and macro- (legislation and state regulation) level.ConclusionsHolding micro-level stakeholder conferences is a valuable method for identifying the most important risk factors to sustainable employment and for developing measures to address them. To implement measures that involve decisions at the meso- or macro-level, representatives from these levels of the healthcare and social system have to be involved.
The role of the multidisciplinary tumor board (MDTB) in the assessment of pancreatic cancer diagnosis and resectability: A tertiary referral center experience
Authors: Quero Giuseppe , De Sio Davide , Fiorillo Claudio , Menghi Roberta , Rosa Fausto , Massimiani Giuseppe , Laterza Vito , Lucinato Chiara , Galiandro Federica , Papa Valerio , Salvatore Lisa , Bensi Maria , Tortorelli Antonio Pio , Tondolo Vincenzo , Alfieri Sergio 
Published: February 2023

BackgroundThe introduction of multidisciplinary tumor boards (MDTBs) for the diagnostic and therapeutic pathway of several oncological disease significantly ameliorated patients' outcomes. However, only few evidences are currently present on the potential impact of the MDTB on pancreatic cancer (PC) management. Aim of this study is to report how MDTB may influence PC diagnosis and treatment, with particular focus on PC resectability assessment and the correspondence between MDTB definition of resectability and intraoperative findings.MethodsAll patients with a proven or suspected diagnosis of PC discussed at the MDTB between 2018 and 2020 were included in the study. An evaluation of diagnosis, tumor response to oncological/radiation therapy and resectability before and after the MDTB was conducted. Moreover, a comparison between the MDTB resectability assessment and the intraoperative findings was performed.ResultsA total of 487 cases were included in the analysis: 228 (46.8%) for diagnosis evaluation, 75 (15.4%) for tumor response assessment after/during medical treatment, 184 (37.8%) for PC resectability assessment. As a whole, MDTB led to a change in treatment management in 89 cases (18.3%): 31/228 (13.6%) in the diagnosis group, 13/75 (17.3%) in the assessment of treatment response cohort and 45/184 (24.4%) in the PC resectability evaluation group. As a whole, 129 patients were given indication to surgery. Surgical resection was accomplished in 121 patients (93.7%), with a concordance rate of resectability between MDTB discussion and intraoperative findings of 91.5%. Concordance rate was 99% for resectable lesions and 64.3% for borderline PCs.ConclusionsMDTB discussion consistently influences PC management, with significant variations in terms of diagnosis, tumor response assessment and resectability. In this last regard, MDTB discussion plays a key role, as demonstrated by the high concordance rate between MDTB resectability definition and intraoperative findings.
Laparoscopic vs. open distal gastrectomy for locally advanced gastric cancer: A systematic review and meta-analysis of randomized controlled trials
Authors: Yan Yong , Ou Caiwen , Cao Shunwang , Hua Yinggang , Sha Yanhua 
Published: February 2023

ObjectiveThe aim of this systematic review and meta-analysis is to compare the short- and long-term outcomes of laparoscopic distal gastrectomy (LDG) with those of open distal gastrectomy (ODG) for patients with advanced gastric cancer (AGC) who exclusively underwent distal gastrectomy and D2 lymphadenectomy in randomized controlled trials (RCTs).BackgroundData in published meta-analyses that included different gastrectomy types and mixed tumor stages prevented an accurate comparison between LDG and ODG. Recently, several RCTs that compared LDG with ODG included AGC patients specifically for distal gastrectomy, with D2 lymphadenectomy being reported and updated with the long-term outcomes.MethodsPubMed, Embase, and Cochrane databases were searched to identify RCTs for comparing LDG with ODG for advanced distal gastric cancer. Short-term surgical outcomes and mortality, morbidity, and long-term survival were compared. The Cochrane tool and GRADE approach were used for evaluating the quality of evidence (Prospero registration ID: CRD42022301155).ResultsFive RCTs consisting of a total of 2,746 patients were included. Meta-analyses showed no significant differences in terms of intraoperative complications, overall morbidity, severe postoperative complications, R0 resection, D2 lymphadenectomy, recurrence, 3-year disease-free survival, intraoperative blood transfusion, time to first liquid diet, time to first ambulation, distal margin, reoperation, mortality, or readmission between LDG and ODG. Operative times were significantly longer for LDG [weighted mean difference (WMD) 49.2 min, p &lt; 0.05], whereas harvested lymph nodes, intraoperative blood loss, postoperative hospital stay, time to first flatus, and proximal margin were lower for LDG (WMD −1.3, p &lt; 0.05; WMD −33.6 mL, p &lt; 0.05; WMD −0.7 day, p &lt; 0.05; WMD −0.2 day, p &lt; 0.05; WMD −0.4 mm, p &lt; 0.05). Intra-abdominal fluid collection and bleeding were found to be less after LDG. Certainty of evidence ranged from moderate to very low.ConclusionsData from five RCTs suggest that LDG with D2 lymphadenectomy for AGC has similar short-term surgical outcomes and long-term survival to ODG when performed by experienced surgeons in hospitals contending with high patient volumes. It can be concluded that RCTs should highlight the potential advantages of LDG for AGC.Systematic Review RegistrationPROSPERO, registration number CRD42022301155.
A New Functional Food Ingredient Obtained from Aloe ferox by Spray Drying
Authors: Comas-Serra Francesca , Martínez-García Juan José , Pérez-Alba Alma , Sáenz-Esqueda María de los Ángeles , Candelas-Cadillo María Guadalupe , Femenia Antoni , Minjares-Fuentes Rafael 
Published: February 2023

Aloe mucilages of Aloe ferox (A. ferox) and Aloe vera (A. vera) were spray-dried (SD) at 150, 160 and 170 °C. Polysaccharide composition, total phenolic compounds (TPC), antioxidant capacity and functional properties (FP) were determined. A. ferox polysaccharides were comprised mainly of mannose, accounting for >70% of SD aloe mucilages; similar results were observed for A. vera. Further, an acetylated mannan with a degree of acetylation >90% was detected in A. ferox by 1H NMR and FTIR. SD increased the TPC as well as the antioxidant capacity of A. ferox measured by both ABTS and DPPH methods, in particular by ~30%, ~28% and ~35%, respectively, whereas in A. vera, the antioxidant capacity measured by ABTS was reduced (>20%) as a consequence of SD. Further, FP, such as swelling, increased around 25% when A. ferox was spray-dried at 160 °C, while water retention and fat adsorption capacities exhibited lower values when the drying temperature increased. The occurrence of an acetylated mannan with a high degree of acetylation, together with the enhanced antioxidant capacity, suggests that SD A. ferox could be a valuable alternative raw material for the development of new functional food ingredients based on Aloe plants.
Orthologs of Human-Disease-Associated Genes in Plants Are Involved in Regulating Leaf Senescence
Authors: Wang Hou-Ling , Yin Weilun , Xia Xinli , Li Zhonghai 
Published: February 2023

As eukaryotes, plants and animals have many commonalities on the genetic level, although they differ greatly in appearance and physiological habits. The primary goal of current plant research is to improve the crop yield and quality. However, plant research has a wider aim, exploiting the evolutionary conservatism similarities between plants and animals, and applying discoveries in the field of botany to promote zoological research that will ultimately serve human health, although very few studies have addressed this aspect. Here, we analyzed 35 human-disease-related gene orthologs in plants and characterized the genes in depth. Thirty-four homologous genes were found to be present in the herbaceous annual plant Arabidopsis thaliana and the woody perennial plant Populus trichocarpa, with most of the genes having more than two exons, including the ATM gene with 78 exons. More surprisingly, 27 (79.4%) of the 34 homologous genes in Arabidopsis were found to be senescence-associated genes (SAGs), further suggesting a close relationship between human diseases and cellular senescence. Protein–protein interaction network analysis revealed that the 34 genes formed two main subnetworks, and genes in the first subnetwork interacted with 15 SAGs. In conclusion, our results show that most of the 34 homologs of human-disease-associated genes in plants are involved in the leaf senescence process, suggesting that leaf senescence may offer a means to study the pathogenesis of human diseases and to screen drugs for the treat of diseases.
Depression Detection on Twitter Social Media Platform using Bidirectional Long-Short Term Memory
Authors: Simanungkalit Andre Agasi , Maharani Warih , Gani Prati Hutari 
Published: February 2023

Depression is one of the mental disorders that are often experienced by a person in daily life. Social media platforms is a new thing as an alternative to tell stories and express current feelings by people today. Twitter is one of the social media that is often used to express feelings and opinions through tweets posts, including tweets that contain hate speech which indirectly shows symptoms of depressive disorder through statements uploaded. It also requires modeling that can recognize users with the potential to experience depression so that they can get initial treatment. This can be implemented using the BiLSTM (Bidirectional Long Short-Term Memory) method and the Word2Vec feature. It can be concluded that the dimensional size of the large feature word2vec, LSTM, and Conv1d layers influenced the model in detecting depression which can be seen in the testing accuracy and F-1 score according to the split data used.
A new look at the process of modelling physical phenomena: Informational approach
Authors: Menin Boris 
Published: February 2023

<p> When building a model of a physical phenomenon or process, scientists face an inevitable compromise between the simplicity of the model (qualitative‒quantitative set of variables) and its accuracy. For hundreds of years, the visual simplicity of a law testified to the genius and depth of the physical thinking of the scientist who proposed it. Currently, the desire for a deeper physical understanding of the surrounding world and newly discovered physical phenomena motivates researchers to increase the number of variables considered in a model. This direction leads to an increased probability of choosing an inaccurate or even erroneous model. This study describes a method for estimating the limit of measurement accuracy, taking into account the stage of model building in terms of storage, transmission, processing and use of information by the observer. This limit, due to the finite amount of information stored in the model, allows you to select the optimal number of variables for the best reproduction of the observed object and calculate the exact values of the threshold discrepancy between the model and the phenomenon under study in measurement theory. We consider two examples: measurement of the speed of sound and measurement of physical constants. </p>
A Review of Generative AI from Historical Perspectives
Authors: dasgupta Dipankar , venugopal deepak , Gupta Kishor Datta 
Published: February 2023

<p>Many applications of Generative AI (such as DALL-E, GPT-3, ChatGPT, etc.) are making headline news in recent months and have been receiving both praise and criticism for their far reaching implications. Some of these applications include query responses, language translation, text to images and videos, composing stories, essays, creating arts and music, generating programs, etc. This review provides an historical background of Generative AI techniques and how they evolved over the years. This report highlights the benefits of Generative AI technologies and their limitations/challenges in moving forward. It is also to be noted that the large-scale applications of AI and their successes are now possible due to exponential advances in hardware (computational power, storage capacity), cloud computing and related operational layers of software.</p>
ДОСЛІДЖЕННЯ ПАРАМЕТРІВ ТЕПЛОВОГО РЕЖИМУ РОБОТИ КАМЕРИ ФЕРМЕНТАЦІЇ
Authors: Терещук М. Б. , Михайлович Я. М. , Четверик Г. О. , Цивенкова Н. М. , Голубенко А. А. , Омаров І. С. 
Published: February 2023

Представлено конструкцію камери ферментації для виробництва компосту з органічної сировини. Досліджено тепловий режим роботи камери на субстраті, який є сумішшю соломи, гною ВРХ, пташиного посліду і деревної тирси. Вологість субстрату становила 62 %. Установка була встановлена на відкритому повітрі. Дослідження виконувалися при температурі від 10 до –10 °С. З метою уникнення теплових втрат камеру ферментації зовні було термоізольовано. Повітря для аерації субстрату підігрівалося до температури від +20 до +60 °С. Введено поняття балансової теплоти. На основі рівняння теплового балансу розроблено математичну модель. Методом проведення багатофакторного експерименту встановлено залежність балансової теплоти від температури повітря аерації суб-страту, товщини шару термоізоляційного матеріалу та температури повітря навколишнього середовища. Встановлено умови, за яких з енергетичної точки зору має місце автономний процес ферментації субстрату: температура повітря на аерацію субстрату – 18…24 °С; температура повітря навколишнього середовища – 1…5 °С; товщина шару ізоляційного матеріалу – 100 мм. Результати експериментального дослідження мають високу відповідність аналітичним даним. Коефіцієнт детермінації склав 0,99. Представлені результати можуть бути використані для подальших досліджень теплового режиму роботи камер ферментації з виробництва компосту з органічної сировини об’ємом до 250 л. Отримані результати дозволяють встановити оптимальну товщину шару ізоляційного матеріалу з урахуванням температурних умов навколишнього середовища, що зменшить непродуктивні втрати теплоти установкою і підвищить ефективність ферментаційної установки в цілому. Подальші дослідження плануються проводитися в напрямі визначення впливу частоти обертання камери ферментації барабанного типу та кількості повітря аерації субстрату на якість виробленого компосту. Бібл. 21, табл. 2, рис. 5.
ANALISIS MODERNISASI IRIGASI DI DAERAH IRIGASI PADUREKSO KABUPATEN PEKALONGAN
Authors: Mindiastiwi Tigo , Purwantini  , Pipit Skriptianata Putra Pranida  
Published: February 2023

Modernisasi irigasi didefinisikan sebagai suatu upaya untuk menciptakan suatu pengelolaan irigasi secara efisien, efektif dan berkelanjutan berdasarkan pada lima pilar modernisasi irigasi. Tujuan dari penelitian ini yaitu untuk menganalisis serta memberikan rekomendasi perencanaan modernisasi irigasi di Daerah Irigasi Padurekso. Survey kondisi eksisiting, investigasi geoteknik, analisis hidrologi dan perhitungan hidrolika dilakukan dalam penelitian ini. Permasalahan utama di D.I Padurekso yaitu distribusi debit air yang tidak merata walaupun debit andalan mencukupi, hal tersebut disebabkan oleh beberapa faktor seperti operasional bangunan bagi sadap yang tidak maksimal, kerusakan atau hilangnya bangunan dan saluran tersier, adanya pemanfaatan air selain untuk pertanian, perkembangan perdagangan yang banyak menutupi jaringan irigasi, dan permukiman yang banyak memanfaatkan lahan pertanian. Sebagain besar jenis tanah merupakan lempung dan pasir serta terdapat sedimentasi yang tinggi. Kebutuhan air di D.I Padurekso untuk saluran sawah 0,78 l/dt.ha, tersier 0,94 l/dt/ha, sekunder 1,08 l/dt/ha, primer 1,19 l/dt/ha dan kolam ikan 0,33 l/dt/ha. Pola tanam yang direncanakan adalah jenis padi – padi – palawija dengan awal tanam pada bulan Oktober. Perencanaan infrastruktur direncanakan untuk menanganai permasalahan di D.I Padurekso.
Kata Kunci: Modernisasi, Irigasi, D.I Padurekso
Effect of Parathion, an Organophosphorous Compound on estrous cycle of female Rattus ratus
Authors: Khasdeo Krishna , Banatwala R. C. , Kavale Rahul M. 
Published: February 2023

20 adult female rats Rattus ratus were exposed with 5 ppm of parathion (organophosphorus compound) for 60 days and their vaginal smears were examined to observe the estrous cycle.It is very axiomatic from the results that estrous cycle has been disrupted in experimental animal treated with parathion, which has been observed by direct fall in number of estrous cycles in treated animal as compared to control.
Mosquito larvivorous potential of some indigenous fishes
Authors: Srivastava Rajiv , Goyal S. K. , Mishra P.K. , Soni Kapil , Saxena R. C. 
Published: February 2023

Natural enemies such as predators play an important role in checking the proferation of vectors in Natural habitat in breeding grounds. Gambusia affinis popularly known as Doctor fish is well known predatory fish can be cultured and used in vector control programme. In the present study, use of 3 indigenous fishes in vector control have been reported. The fishes were recovered from Machna river and used in the laboratory to control Anophelese stephensi and Aedes aegypti larvae. Laboratory testing in glass aquarium contaning 5 fishes of each Ajystus cavasius, Danio devario, Rasbora daniconius alongwith Gambusia affinis, revealed that as far as predatory efficacy is concerned Mystus cavasius stands 1st and consumed 130 larvae/day/fish. It was noticed during the course of experiment that fishes prefer I/II instar larvae than III/ IVth instar larvae of both the species. The study was also conducted with and without fish food. To observe larvivorous potential. It was noticed that fish food has some effect on the predatory habit of these fishes. In the presence of fish food, the predatory period was found to be increased by 5 minutes to 20 minutes more. Gut content analysis of the fishes showed not only the mosquito larvae but some nematodes, annelids. beetles, algae and unidentified material. The result of the present study thus suggest that indigenous fishes edible value can be cultured in small ponds and other water bodies to reduce the vector bone diseases. Without disturbing the ecosystem and causing no ill effect to the human health.
Assessment of noise pollution in the city of Hardwar (Uttaranchal) India
Authors: Khanna D. R. , Singh J. P. , Singh Shakun 
Published: February 2023

A study has been made to assess the noise pollution at six places of Hardwar city. Study was carried out for the period of three to five hours on 25th May-2002 for the parameters average, minimum and maximum noise in different categorized area. The results revealed that minimum and maximum pollution of noise varied between 56.1 to 83.6 dB(A) Leq.in the city. The present paper will be key for the awareness of public and authorities to take an action for control of noise pollution creators.
BUDIDAYA SAYURAN SISTEM HIDROPONIK DI KELURAHAN PARDOMUAN KECAMATAN SIANTAR TIMUR KOTA PEMATANGSIANTAR
Authors: Ummu Harmain  , Saragih Jef Rudiantho 
Published: February 2023

The limited land available has made the community less interested in farming. Even the small amount of household vegetable needs is obtained from markets and stalls. For this reason, the community needs to be given knowledge of vegetable farming by utilizing existing land so that at least it is able to meet the family's vegetable needs and if possible can increase household income. The output plan for this activity is: (1) Participants have technical skills in cultivating several types of vegetables; (2) Participants have technical knowledge and skills of hydroponic system vegetable cultivation; (3) Participants are able to produce several types of fresh vegetables; (4) Participants receive additional income; and (5) The local area can become a demonstration plot for similar activities. Methods and outcomes of activities: extension (100%), hydroponic vegetable cultivation practice (100%), sales (25%), and promotion activities (25%). The results and outcomes obtained in the community service activities carried out include increased public understanding of vegetable cultivation and hydroponic systems, vegetable self-sufficiency, utilization of empty space in the yard.
Measuring children’s sustained selective attention and working memory: validity of new minimally linguistic tasks
Authors: Ebert Kerry Danahy , Pham Giang T. , Levi Sophie , Eisenreich Benjamin 
Published: February 2023

AbstractThis study introduces visual tasks using nonlinguistic stimuli that measure sustained selective attention (SSA) and working memory (WM), two constructs foundational to learning and associated with developmental disorders in children. Using an argument-based approach to validation, we examine whether each task (a) measures distinct constructs, (b) shows internal consistency, (c) captures a range of performance, and (d) relates to development as indexed by age. Participants included 71 children, ages 4–10, of whom 12 had parental concern for language/learning. The SSA task presented spatial locations within a long and uninteresting task, following the continuous performance task paradigm. The WM task presented paired location sequences of increasing length, incorporating key elements of the n-back and complex span paradigms. Controlling for age, tasks were found to be minimally associated with each other (r = .26), suggesting related but distinct constructs. Internal consistency was high, with split-half reliability of .94 (SSA) and .92 (WM); the stability of these estimates was supported by bootstrapping simulations. Task performance was evenly distributed, with minimal floor or ceiling effects within this age range. Performance was positively related to age (SSA r = .49; WM r = .53). Exploratory correlations with a measure of parental concern were significant for SSA but not WM. The results show that these new tasks can be used to measure children’s SSA and WM in a visual domain with minimal linguistic influence. These tasks capture developmental changes in the early school years. Further investigation can examine their utility for classifying children with developmental disorders.