bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bi‐Deficiency Leading to High‐Performance in Mg3(Sb,Bi)2‐Based Thermoelectric Materials
Authors: Li Jing‐Wei , Liu Weishu , Xu Wei , Zhuang Hua‐Lu , Han Zhijia , Jiang Feng , Zhang Peng , Hu Haihua , Gao Hanbin , Jiang Yilin , Cai Bowen , Pei Jun , Su Bin , Li Qian , Hayashi Kei , Li Hezhang , Miyazaki Yuzuru , Cao Xingzhong , Zheng Qiang , Li Jing‐Feng 
Published: March 2023

AbstractMg3(Sb,Bi)2 is a potential nearly‐room temperature thermoelectric compound composed of earth‐abundant elements. However, complex defect tuning and exceptional microstructural control are required. Prior studies have confirmed the detrimental effect of Mg vacancies (VMg) in Mg3(Sb,Bi)2. This study proposes an approach to mitigating the negative scattering effect of VMg by Bi deficiency, synergistically modulating the electrical and thermal transport properties to enhance the thermoelectric performance. Positron annihilation spectrometry and Cs‐corrected scanning transmission electron microscopy analyses indicated that the VMg tends to coalesce due to the introduced Bi vacancies (VBi). The defects created by Bi deficiency effectively weaken the scattering of electrons from the intrinsic VMg and enhance phonon scattering. A peak zT of 1.82 at 773 K and high conversion efficiency of 11.3% at ∆T = 473 K are achieved in the optimized composition of Mg3(Sb,Bi)2 by tuning the defect combination. This work demonstrates a feasible and effective approach to improving the performance of Mg3(Sb,Bi)2 as an emerging thermoelectric material.
Resonant‐Cavity‐Enhanced Electrochromic Materials and Devices
Authors: Chen Jian , Song Ge , Cong Shan , Zhao Zhigang 
Published: March 2023

AbstractWith rapid advances in optoelectronics, electrochromic materials and devices have received tremendous attentions from both industry and academia for their strong potentials in wearable and portable electronics, displays/billboards, adaptive camouflage, tunable optics, and intelligent devices, etc. However, conventional electrochromic materials and devices typically present some serious limitations such as undesirable dull colors, and long switching time, hindering their deeper development. Optical resonators have been proven to be the most powerful platform for providing strong optical confinement and controllable lightmatter interactions. They generate locally enhanced electromagnetic near‐fields that can convert small refractive index changes in electrochromic materials into high‐contrast color variations, enabling multicolor or even panchromatic tuning of electrochromic materials. Here, resonant‐cavity‐enhanced electrochromic materials and devices, an advanced and emerging trend in electrochromics, are reviewed. In this review, w e will focus on the progress in multicolor electrochromic materials and devices based on different types of optical resonators and their advanced and emerging applications, including multichromatic displays, adaptive visible camouflage, visualized energy storage, and applications of multispectral tunability. Among these topics, principles of optical resonators, related materials/devices and multicolor electrochromic properties are comprehensively discussed and summarized. Finally, the challenges and prospects for resonant‐cavity‐enhanced electrochromic materials and devices are presented.
Thermally Activated Delayed Fluorescence and Room‐Temperature Phosphorescence in Sulfidoazatriangulene‐Based Materials and their S‐oxides
Authors: Elgadi Seja A. , Mayder Don M. , Hojo Ryoga , Hudson Zachary M. 
Published: March 2023

AbstractStructural constraint is an emerging strategy for improving the photoluminescence quantum yield, molar absorptivity, and color purity of luminescent materials. In this report, emitters displaying thermally activated delayed fluorescence (TADF) are achieved for the first time using the planarized donor sulfidotetramethyazatriangulene (SMAT). Compared to non‐planarized phenothiazine (PTZ) donors, the enhanced rigidity of SMAT contributes to improved color purity and photoluminescence quantum yield, with up to 90% quantum yield observed for donor–acceptor compounds in toluene solution. Planarized SMAT‐based emitters also offer up to tenfold enhancement in two‐photon absorption cross‐section compared to analogous PTZ‐based materials. Oxidation of sulfur‐containing donors to sulfoxide and sulfone derivatives is demonstrated as a simple and generalizable means of tuning the electron‐donating ability of sulfur‐containing moieties. SMAT‐TRZ and SOMAT‐TRZ both exhibit TADF, with green and blue emission, respectively, while SO2MAT‐TRZ displays blue room temperature phosphorescence. Overall, this work demonstrates that SMAT and its S‐oxides can be used to design high‐performance luminescent materials with emergent properties such as TADF or room‐temperature phosphorescence.
Inkjet‐Printed Microlenses Integrated onto Organic Photodiodes for Highly Accurate Proximity Sensing
Authors: Seiberlich Mervin , Zhang Qiaoshuang , Tunc Ali Veysel , Xia Kai , Ruiz‐Preciado Luis Arturo , Schlisske Stefan , Falis Konstantinos , Strobel Noah , Lemmer Uli , Hernandez‐Sosa Gerardo 
Published: March 2023

AbstractThe current needs for optical detectors in industrial and consumer electronics require sensors with thin form‐factors, high performance and a facile fabrication and integration. In this work, the integration of inkjet printed microlenses onto solution‐processed organic photodiodes is demonstrated to enable high‐accuracy proximity sensing via the focused induced photoresponse (FIP) effect. By precisely controlling the ink deposition and substrate properties, it is able to tune the microlens focal length from 150 to 775 μm. This allows to the appropriate microlens design to be chosen to take advantage of the FIP effect. By comparing the photocurrent ration of a device with and without microlenses, absolute proximity measurements in the range of 100 μm to 4 mm are achieved. Champion devices yield an accuracy of down to ±50 μm within three standard deviations (3σ). These results highlight the potential of the microlens‐OPD integration for highly accurate and close‐distance proximity applications in a variety of fields.
Regulating Polaron Transport Regime via Heterojunction Engineering in Cove‐Type Graphene Nanoribbons
Authors: Cassiano Tiago de Sousa Araújo , Júnior Luiz Antônio Ribeiro , Silva Geraldo Magela e , Neto Pedro Henrique de Oliveira 
Published: March 2023

AbstractGraphene nanoribbons (GNRs) are emerging materials inheriting excellent properties from graphene while potentially exhibiting semiconducting behavior. All these features sparked numerous efforts to insert GNRs in nanoelectronics. As a result, synthesis routes with atomic resolution are now a reality. Recently, the rise of heterojunction (HJ) engineering pushed even further the prospects, allowing the blending of different GNRs as building blocks. However, much of the potential behind it remains untouched for some junctions. In this work, the consequences of forming a cove‐type GNR (CGNR) HJ by assembling specimens with borders of different zig‐zag/armchair ratios are explored. The nanoribbons are simulated using the extended two‐dimensional Su–Schrieffer–Heeger model with electron–phonon coupling. The findings show that manipulating the junction creates multiple routes for smooth monotonic gap tuning. Moreover, the changes in the hopping mechanism, mobility, and effective mass are reported leading to variations up to 10 000 cm2 V−1 s−1 and 0.425 me. This work reveals a pathway to expand the modularity of CGNRs through smooth control of the charge carrier's properties. Future applications can explore this feature to design devices with highly specific charge transport characteristics. The study also serves as theoretical background, potentially inspiring new tuning strategies in other GNRs.
High‐depth next‐generation sequencing panel testing in the evaluation of arteriovenous malformations
Authors: Hernandez Patricia V. , King Katherine A. , Evenson Michael J. , Corliss Meagan M. , Schroeder Molly C. , Heusel Jonathan W. , Neidich Julie A. , Cao Yang 
Published: March 2023

AbstractArteriovenous malformations (AVMs) are vascular lesions in which an overgrowth of blood vessels of varying sizes develops with one or more direct connections between the arterial and venous circulation. We performed a retrospective review of a cohort of 54 patients with AVMs referred to our clinical genomic laboratory for high‐depth next‐generation sequencing (NGS) panel of Disorders of Somatic Mosaicism (DoSM). Thirty‐seven of 54 patients were female (68.5%). Among the 54 cases, 37 (68.5%) cases had pathogenic and/or likely pathogenic (P/LP) variants identified, two cases (3.7%) had variants of uncertain clinical significance, and the remaining 15 cases (27.8%) had negative results. MAP2K1 variants were found in 12 cases, followed by eight cases with KRAS variants and seven with TEK variants, and the remainder being identified in several other genes on the panel. Among the 37 positive cases, 32 cases had somatic alterations only; the remaining five cases had at least one germline P/LP variant, including four cases with PTEN and one with RASA1. Of note, two cases had the unexpected co‐existence of two P/LP variants. In summary, this study illustrated the molecular diagnostic yield (68.5%) of this cohort of patients with a clinical indication of AVMs by our high‐depth DoSM NGS panel.
Construction of Bis‐Indole Derivatives Using α‐Amylase Enzyme: Application in the Gram‐Scale Synthesis of Bis‐Indole Containing Bioactive Molecules
Authors: Kamboj Priya , Tyagi Vikas 
Published: March 2023

AbstractHerein, we have developed a biocatalytic approach toward the synthesis of bis(indolyl)methane using an α‐amylase in water. This protocol has a number of advantages like eco‐friendly reaction conditions, use of biodegradable catalyst, and higher conversion. Moreover, the generality of this protocol was displayed by employing various substitutions on indole and benzaldehyde which provides the corresponding products in very good yield (63–89%). Also, the applicability of this protocol was shown by synthesizing four different bioactive molecules on a gram scale.
Dots on a screen: The past, present, and future of morphometrics in the study of nonavian dinosaurs
Authors: Hedrick Brandon P. 
Published: March 2023

AbstractUsing morphometrics to study nonavian dinosaur fossils is a practice that predates the origin of the word “dinosaur.” By the 1970s, linear morphometrics had become established as a valuable tool for analyzing intra‐ and interspecific variation in nonavian dinosaurs. With the advent of more recent techniques such as geometric morphometrics and more advanced statistical approaches, morphometric analyses of nonavian dinosaurs have proliferated, granting unprecedented insight into many aspects of their biology and evolution. I outline the past, present, and future of morphometrics as applied to the study of nonavian dinosaurs zeroing in on five aspects of nonavian dinosaur paleobiology where morphometrics has been widely utilized to advance our knowledge: systematics, sexual dimorphism, locomotion, macroevolution, and trackways. Morphometric methods are especially susceptible to taphonomic distortion. As such, the impact of taphonomic distortion on original fossil shape is discussed as are current and future methods for quantifying and accounting for distortion with the goal of reducing the taphonomic noise to biological signal ratio. Finally, the future of morphometrics in nonavian dinosaur paleobiology is discussed as paleobiologists move into a “virtual paleobiology” framework, whereby digital renditions of fossils are captured via methods such as photogrammetry and computed tomography. These primary data form the basis for three‐dimensional (3D) geometric morphometric analyses along with a slew of other forms of analyses. These 3D specimen data form part of the extended specimen and help to democratize paleobiology, unlocking the specimen from the physical museum and making the specimen available to researchers across the world.
An examination of stimulus technology level and preference displacement during multiple stimulus without replacement preference assessments
Authors: Hoffmann Audrey N. , Paskins Ryan T. , Brady‐Ruehs Anna M. , Sellers Tyra P. 
Published: March 2023

AbstractResearchers have observed that preference for edible items may displace preference for leisure items when items from the stimulus classes are assessed together within multiple stimulus without replacement (MSWO) preference assessments. The current study extends previous research by examining patterns of preference and displacement when assessing preference for high‐tech and low‐tech leisure items. We conducted three separate MSWO preference assessments; one assessing low‐tech items, another assessing high‐tech items, and a combined assessment (using the top four high‐ and low‐tech items from the previous assessments) to test for displacement. Preference for high‐tech items fully or partially displaced preference for low‐tech items in five of eight participants. We then conducted concurrent and single operant reinforcer assessments using the highly preferred high‐tech and low‐tech items. Reinforcer assessment results demonstrated similar levels of responding for the highest preferred high‐tech and low‐tech items, indicating that combining high‐ and low‐tech items within preference assessments may influence the validity of results.
Lower 24‐h urinary potassium excretion is associated with higher prevalent depression and anxiety status in general population
Authors: Wu Zihao , Heizhati Mulalibieke , Hu Junli , Lin Mengyue , Gan Lin , Li Mei , Yang Wenbo , Yao Ling , Hong Jing , Sun Le , Li Jing , Li Wei , Li Nanfang 
Published: March 2023

AbstractBackgroundUncertainty remains about the association of potassium (K) intake with depression and anxiety status. We explored their relationship using 24‐h urinary K, reflecting K intake, in general population.MethodsWe collected 24‐h urine and performed self‐rating depression and anxiety scales (SDS, SAS) cross‐sectionally in adults selected by random sampling in China. SDS and SAS standard score ≥50 defined depression and anxiety status. Participants were divided into three groups (T1, T2, and T3) by 24‐h urinary K tertile. Odds ratios (OR) and 95% confidence intervals were calculated. Sensitivity analysis was performed by excluding anti‐hypertensive agent takers.Results546 participants comprised current analytical sample. First, T1 and T2 groups showed higher SDS scores (40.0 vs 40.0 vs 36.0, p = .001), prevalence (19.8 vs 15.9 vs 7.1%, p = .002), whereas increased adjusted odds for depression status only in T1 group (OR = 2.71, p = .017), compared with T3 group. Second, T1 and T2 groups showed higher SAS scores (38.0 vs 40 vs 35.0, p < .001) and prevalence (14.8 vs 21.4 vs 8.8%, p = .003), whereas increased adjusted odds for anxiety status only in T2 group (OR = 2.07, p = .042), compared with T3 groups. Third, T1 and T2 groups showed higher prevalence (10.4% vs 11.5% vs 2.7%, p = .004) and adjusted odds (OR = 3.71, p = .013; OR = 3.66, p = .014) for co‐existent anxiety and depression status, compared with T3 group. Most results remained consistent in sensitivity analysis.ConclusionsLower K intake is implicated in presence of anxiety and depression status in general population; this may provide basis for programs to increase K intake and prevent disease.
Causes of death in endometrial cancer survivors: A Surveillance, Epidemiology, and End Result–based analysis
Authors: Xue Qing , Che Wenqiang , Xue Lujiadai , Zhang Xian , Wang Xiaoyu , Lyu Jun 
Published: March 2023

AbstractBackgroundIncreasing attention has been paid to the survival of endometrial cancer (EC) patients, but the non‐cancer causes of death from EC are rarely reported. This study primarily aimed to investigate the non‐cancer causes of death in patients with EC.MethodsThe study collected relevant data, including age, tumour stage and treatment mode, on patients diagnosed with endometrial malignancies from 2000 to 2015 in the Surveillance, Epidemiology, and End Results (SEER) Programme. We analysed the standardised mortality ratio (SMR) to determine the cause of death.ResultsThe study included 135,831 patients with EC. During the follow‐up, 46,604 (34.3%) patients died, of whom 42.9%, 15.6% and 41.5% died of EC, other cancers and non‐cancer causes, respectively. As the diagnosis time increased, the number of EC‐associated mortalities gradually decreased. The most common non‐cancer causes of death were heart disease, cerebrovascular disease and diabetes. Regarding the general population of the United States, patients with EC died of heart disease (SMR: 1.06; 95% confidence interval [CI]: 1.03–1.09), diabetes (SMR: 1.56; 95% CI: 1.47–1.65) and septicaemia (SMR: 1.40; 95% CI: 1.28–1.52), which were statistically significant.ConclusionsFor patients with EC, the number of deaths from non‐cancer causes (mainly heart disease, cerebrovascular disease and diabetes mellitus) is equivalent to that of EC. In addition, compared with the general population, EC survivors have a higher risk of death from sepsis and diabetes. These discoveries support how survivors can avoid future‐related health risks. By doing this, clinicians can improve the quality of life and chances of the survival of patients with EC.
A novel prognostic model based on ferritin and nomogram‐revised risk index could better stratify patients with extranodal natural killer/T‐cell lymphoma
Authors: Liu Xindi , Liang Yuanzheng , Shen Ziyuan , Wei Liqiang , Yang Jing , Piao Yingshi , Sang Wei , Li Pengfei , Wang Liang 
Published: March 2023

AbstractBackgroundExtranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is an aggressive lymphoma with marked heterogeneity, resulting in a distinct prognosis even in patients with the same disease stage. The nomogram‐revised risk index (NRI) has been proposed to stratify patients with ENKTCL. Numerous reports have revealed the prognostic role of serum ferritin in various cancers.PurposeWe aimed to evaluate the role of NRI in our single cohort of patients with ENKTCL treated uniformly, explore the prognostic value of ferritin, and establish a new prognostic model to better stratify patients with ENKTCL.MethodsWe included 326 patients with ENKTCL with detailed data regarding clinical characteristics and survival outcomes. All patients were treated with asparaginase‐based chemotherapy with or without radiotherapy. Multiple R packages were used to analyze the prognostic factors and derive a novel prognostic model.ResultsIn the training cohort comprising 236 patients with ENKTCL, NRI significantly correlated with progression‐free survival (PFS) and overall survival (p < 0.0001). Using a ferritin level of 400 μg/L as the cutoff value, patients with high ferritin levels had significantly inferior PFS (p = 0.00028). Integrating the NRI score and four easily accessible clinical parameters, namely ferritin, hemoglobin, albumin, and D‐dimer, a new prognostic model was constructed, stratifying patients with ENKTCL into three risk groups. This new prognostic model was independent of disease stage and NRI and performed better than NRI. Furthermore, this model helped to stratify patients within the same NRI risk groups. Finally, the role of this novel prognostic model was validated in the external validation cohort comprising 90 patients with ENKTCL.ConclusionsSerum ferritin level could be a novel prognostic factor in patients with ENKTCL. The new prognostic model combining NRI and clinical parameters could better predict the prognosis of ENKTCL, thereby warranting further validation and potentially guiding individualized treatment in future prospective clinical trials.
Multiple hydatid cyst disease revealed by an expansive intracranial process: A case report
Authors: Nechi Salwa , Gharbi Ghada , Douggaz Amel , Belfekih Houda , Chaabane Abir , Mfarrej Mohamed Karim , Chelbi Emna 
Published: March 2023

AbstractHydatid disease is a real public health problem in developing countries. Cerebral localization is rare; it does not exceed 2%. It is more frequent in children and adolescents. It is often primary in children. In adults, it is less frequent and generally associated with other localizations. We report the case of a 60‐year‐old Tunisian patient with pulmonary, hepatic and cerebral hydatid cyst, revealed by neurological symptoms with an expansive intracranial process on brain imaging.
Extensive right‐sided endocarditis in double‐chamber right ventricle presented with leukocytoclastic vasculitis
Authors: Nakhaee Akram , Koohsari Parisa , Rahmanian Mehrzad , Sardari Akram , Parkhideh Roya , Larti Farnoosh 
Published: March 2023

AbstractCongenital heart disease is a risk factor for infective endocarditis (IE). Ventricular septal defects and ventricular outflow tract obstructions are this population's most common causes of endocarditis. We present a patient diagnosed with leukocytoclastic vasculitis, renal, and pulmonary involvement with right‐sided IE as an etiology for vasculitis.
Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed‐Release Formulation of Esomeprazole in Healthy Subjects
Authors: Hwang Sejung , Hong Sung Hee , Jung Jina , Chung Jae‐Yong , Jang In‐Jin , Lee SeungHwan 
Published: March 2023

AbstractA novel dual delayed‐release formulation (DR) of esomeprazole was developed to prolong the effect of esomeprazole inhibiting gastric acid secretion. This study investigated the effect of food on the pharmacokinetics (PK) and pharmacodynamics (PD) of DR esomeprazole. A randomized, open‐label, single‐dose, 2‐period, 2‐sequence crossover study was conducted in healthy Korean subjects. Subjects were orally administered a single dose of 40‐ mg DR esomeprazole in fasted and fed states in each period. PK and PD characteristics evaluated through continuous 24‐hour intragastric pH monitoring in fasted and fed states were compared between the 2 conditions. A total of 23 subjects completed the study and were included in the PK analysis. PD analysis was conducted in 21 subjects, excluding 2 subjects, because of inappropriate pH profiles. The systemic exposure of esomeprazole after a single dose of DR esomeprazole in the fed state decreased compared to that in the fasted state. However, the percentage decrease from baseline in integrated gastric acidity and the percentage of time at pH ≥4 were not significantly different between the 2 conditions. In conclusion, although the systemic exposure of esomeprazole decreased when DR esomeprazole was administered in the fed state compared to that in the fasted state, the degree of gastric acid secretion inhibition was not clinically different, regardless of food intake.