bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on fault diagnosis method of bearing based on parameter optimization VMD and improved DBN
Authors: Sun Yingqian , Jin Zhenzhen 
Published: September 2023

Aiming at the problem that the bearing characteristics are difficult to extract accurately, and the fault diagnosis is difficult. This paper proposed a novel bearing fault diagnosis method with parameter optimization variational mode decomposition (VMD) and particle swarm optimization Deep Belief Networks (PSO-DBN). Firstly, the PSO is applied to optimize the parameter of the VMD and solve the problem of parameter setting of the VMD. Then, to effectively extract the feature information, using the optimized VMD, the original signal is decomposed into intrinsic mode components, and each component's dispersion entropy (DE) value is calculated. Finally, to further improve the accuracy of fault diagnosis, the PSO-DBN model is used to recognize the fault pattern bearing. The results of both experiments are 100 %. The results show that this method can effectively extract bearing fault features and accurately realize fault diagnosis. Compared with other methods, the accuracy of this method is increased by at least 2.08 % and the maximum is increased by 33.33 %.
Differential utilisation of dissolved organic matter compound fractions by different biofilter microbial communities
Authors: Vignola Marta , Lenselink Jeanine , Quinn Dominic , Ijaz Umer Zeeshan , Pereira Ryan , Sloan William T. , Connelly Stephanie , Moore Graeme , Gauchotte-Lindsay Caroline , Smith Cindy J. 
Published: September 2023

Abstract

Dissolved organic matter (DOM) is a complex mixture of carbon-based compounds present in natural aquatic systems, which significantly affects drinking water treatment processes. Biofiltration, utilising biologically active beds of porous medium, offers a low-energy and low-chemical solution for controlling bioavailable DOM. However, the impact of microbial community composition on DOM degradation in biofilters remains poorly understood. This study aimed to explore the abilities of microbial communities from the top, middle, and bottom (TOP, MID, and BOT) of a biofilter to process DOM. We showed varying growth rates on the DOM, with bottom community exhibiting the highest cell abundance at the end of the experiment (1.83 × 106 ± 9 × 103; 2.06 × 106 ± 1 × 104; 2.15 × 106 ± 7 × 103 cells/mL for the TOP, MID, and BOT, respectively). The three communities showed different preferences for utilising specific DOM fractions, with the bottom community targeting more complex ones. The microbial communities from the bottom of the biofilter had a higher relative abundance of the Curvibacter genus, suggesting it could play a crucial role in degrading complex DOM fractions. These findings highlight the influence of microbial community composition on DOM degradation in biofilters, providing valuable insights for optimising their performance.
Toward sustainable landscape irrigation using a novel design for water collection systems that use atmospheric moisture condensation
Authors: Aldeek Zaid A. O. 
Published: September 2023

Abstract

This paper introduces a novel design that uses high-emissivity materials with no hydrophobic surfaces to increase the speed of condensation and the dropping-off process in water collection systems from atmospheric moisture. The design incorporates simple and low-cost technology that takes advantage of advanced material properties to enable sustainable irrigation in regions characterized by water resource scarcity, generally favoring greening. The concept is based on the application of universal physics principles such as dew point, wetting and antiwetting, and material emissivity coefficients. The innovative collection system design and experimentation confirm the feasibility of collecting water from the air in various semi-arid regions with a low number of rainy days. The first novel aspect of the collection system design is the rapid increase in condensation and the use of materials with a high capacity to release collected water to address unwanted evaporation. The second novel feature is that the volume is reduced, and the system is flexible and inexpensive, allowing it to be distributed across a specific landscape. Reduced construction costs and ease of use demonstrate the real possibility of its use in developing and poor countries to first increase vegetation diffusion and then contribute to sustainable agriculture and green architecture.
Construction of RNA Methylation Modification-immune-related
lncRNA Molecular Subtypes and Prognostic Scoring System in Lung
Adenocarcinoma
Authors: Wang Jiajing , Shu Jianfeng 
Published: September 2023

Background:
RNA methylation modification is not only intimately interrelated
with cancer development and progression but also actively influences immune cell infiltration
in the tumor microenvironment (TME). RNA methylation modification genes
influence the therapeutic progression of lung adenocarcinoma (LUAD), and mining RNA
methylation modification prognosis-related markers in LUAD is crucial for its precise
prognosis.

Methods:
RNA-Seq data and Gene sets were collected from online databases or published
literature. Genomic variation analysis was conducted by the Maftools package.
RNA methylation-immune-related lncRNAs were obtained by Pearson correlation analysis.
Then, Consistent clustering analysis was performed to obtain RNA methylation modification-
immune molecular subtypes (RMM-I Molecular subtypes) in LUAD based on selected
lncRNAs. COX and random survival forest analysis were carried out to construct
the RMM-I Score. The receiver operating characteristic (ROC) curve and Kaplan Meier
survival analysis were used to assess survival differences. Tumor immune microenvironment
was assessed through related gene signatures and CIBERSORT algorithm. In addition,
drug sensitivity analysis was executed by the pRRophetic package.

Results:
Four RNA methylation modified-immune molecular subtypes (RMM-I1, RMM-
I2, RMM-I3, RMM-I4) were presented in LUAD. Patients in RMM-I4 exhibited excellent
survival advantages and immune activity. HAVCR2, CD274, and CTLA-4 expression
were activated in RMM-I4, which might be heat tumors and a potential beneficial
group for immunotherapy. OGFRP1, LINC01116, DLGAP1-AS2, CRNDE, LINC01137,
MIR210HG, and CYP1B1-AS1 comprised the RMM-I Score. The RMM-I Score exhibited
excellent accuracy in the prognostic assessment of LUAD, as patients with a low RMM-
I Score exhibited remarkable survival advantage. Patients with a low RMM-I score
might be more sensitive to treatment with Docetaxel, Vinorelbine, Paclitaxel, Cisplatin,
and immunotherapy.

Conclusion:
The RMM-I molecular subtype constituted the novel molecular characteristic
subtype of LUAD, which complemented the existing pathological typing. More
refined and accurate molecular subtypes provide help to reveal the mechanism of LUAD
development. In addition, the RMM-I score offers a reliable tool for accurate prognosis
of LUAD.
Influence of Drying Conditions on Physicochemical, Phytochemical, and
Antioxidant Properties of Medicinal Plant Stem Xáo Tam Phân
(Paramignya trimera) Grown in Vietnam
Authors: Nguyen Van Tang , Tran Thanh Giang , Nguyen Van-Thi , Tran Ngoc Le , Nguyen Van Hoa 
Published: September 2023

Introduction:
This study aimed to assess the physicochemical, phytochemical, and antioxidant
properties of medicinal plant stem Xáo tam phân (Paramignya trimera) as influenced by
11 drying conditions. Xáo tam phân (Paramignya trimera (Oliv.) Guillaum) has been used in fold
medicine for cancer prevention and treatment. The preparation of the dried sample is crucial and
necessary for further investigation and application. To evaluate the effects of some popular drying
methods, namely, sun drying, hot-air drying, microwave drying, infrared drying, and freeze drying
on the physicochemical properties, the retention of phytochemical compounds (total saponins,
phenolics, and flavonoids), and antioxidant properties (DRSC, CUPRAP, and FRAP) of dried P.
trimera stem.

Methods:
The plant stem Xáo tam phân (Paramignya trimera) was dried by 11 drying conditions:
sun drying at 36.6°C; hot-air drying at 60°C, 80°C, and 100°C; microwave drying at 270 W, 450
W, and 720 W; infrared drying at 40°C, 45°C, and 50°C; and freeze drying at -40°C.

Results:
The results show that among the 11 drying conditions used, hot-air drying at 80°C
achieved the highest phytochemical contents of the P. trimera stem in terms of total saponins
(28.82 mg EE/g DS), total phenolics (3.71 mg GAE/g DS), and total flavonoids (10.82 mg CE/g
DS), and infrared drying at 50°C possessed the greatest antioxidant activity of the P. trimera stem
(3.59 and 9.56 mg TE/g DS for DRSC and CUPRAC, respectively); however, both these drying
methods had the longest drying time (1.5 to 7.0 h.) and consumed the highest energy (2.10 to
11.77 kWh). In contrast, microwave drying took the shortest drying time (0.1 to 0.4 h.) and consumed
the least energy (0.07 to 0.14 kWh), but it still retained moderate levels of phytochemical
compounds and antioxidant activity of the P. trimera stem.

Conclusion:
The findings achieved from this study recommend using hot-air drying at 80°C for
the preparation of the dried sample from the P. trimera plant stem.
The Effectiveness of Telephone-based Psychological Services to COVID-19
Authors: Khademi Mojgan , Vaziri-Harami Roya , Mashadi Amin Mahouram , Seif Pegah , Babazadehdezfoly Abbas 
Published: September 2023

Background:
The COVID-19 pandemic has disrupted the delivery of mental health services, leading to the development of telepsychiatry.

Aim:
The present study investigates the effectiveness of telephone-delivered treatment for psychological disorders of COVID-19 survivors in Tehran, the capital of Iran.

Methods:
In this non-randomized controlled trial, 91 COVID-19 survivors, primarily residents were enrolled. Participants completed a baseline questionnaire and a psychological screening questionnaire. The intervention included the telephone-based psychological services provided by trained psychiatric residents. The Post-Traumatic Stress Disorder (PTSD) Checklist (PCL) was administered to assess the presence of PTSD symptoms. Symptoms of anxiety and depression were measured by the Patient Health Questionnaire.

Results:
The General Health Questionnaire (GHQ) adjusted mean difference was significantly lower in the intervention group than in the control group. There was a significant negative correlation between the Spost-GHQ score and history of going to the clinic and history of psychiatric disorders, but no relationship with the history of hospitalization. All participants completed the satisfaction form, with almost half of them being “satisfied” or “very satisfied” with the telehealth calls.

Conclusion:
Telephonic delivery of psychological services showed an effective way of providing evidence-based psychological support during the pandemic. This telehealth program can offer much-needed assistance to individuals with COVID-19 improving their psychological wellbeing.
Value of the A2DS2 Score Combined with the Neutrophil-to-lymphocyte Ratio in Predicting Acute Ischemic Stroke-associated Pneumonia
Authors: Liang Chunhua , Xiao Xiaoyong , Xiao Xiaohua , Yan Xueqin , Hu Huoyou , Tian Jing , Wei Cuimei 
Published: September 2023

Objective:
We aimed to explore the risk factors for acute ischemic stroke-associated pneumonia (SAP) and evaluate the predictive value of the Age, Atrial fibrillation, Dysphagia, Sex, Stroke Severity (A2DS2) score, neutrophil-to-lymphocyte ratio (NLR), and a combination of both indices for acute ischemic SAP.

Methods:
Overall, 1,505 patients with acute ischemic stroke (AIS) were enrolled and divided into SAP and non-SAP groups. Patients’ age, sex, and medical history (alcohol consumption, hypertension, diabetes, hyperlipidemia, coronary disease, atrial fibrillation, chronic obstructive pulmonary disease, and stroke history) were recorded. Clinical data were recorded, including consciousness disturbance, dysphagia, indwelling nasogastric tube, thrombolytic therapy, hospital stay length, National Institute of Health Stroke Scale (NIHSS) score, stroke position, TOAST classification, and blood pressure on admission. Laboratory indicators, including white blood cell (WBC) count, neutrophil count, lymphocyte count, creatinine, homocysteine, and fasting blood glucose, were also recorded. NLR was calculated by dividing the absolute neutrophil count by the absolute lymphocyte count. All patients were scored using A2DS2. Binary logistic regression was used to analyze the relationships between A2DS2, NLR, and SAP. Receiver operating characteristic (ROC) curves were generated to evaluate the diagnostic value of A2DS2, NLR, and their combined indices for predicting SAP.

Results:
SAP occurred in 203 (13.5%) of the 1,505 enrolled patients. Patients in the SAP group were older and had a higher proportion of hypertension and chronic obstructive pulmonary disease history, consciousness disorder, dysphagia, indwelling nasogastric tube, fasting blood glucose level, NIHSS score, and longer hospital stay. The SAP group had a higher A2DS2 score than the non-SAP group. Similarly, the WBC count, neutrophil count, and NLR were significantly higher in the SAP group than in the non-SAP group. After excluding confounding factors, binary logistic regression analysis showed that age, NIHSS score, NLR, and A2DS2 score were independent risk factors for SAP. The ROC curves showed the A2DS2 score and NLR predicted SAP with an area under the curve (AUC) of 0.855 (sensitivity: 73.3%, specificity: 86.1%) and 0.849 (sensitivity: 79.7%, specificity: 80.6%), respectively, and the combined prediction of SAP AUC was 0.924 (sensitivity: 87.7%, specificity: 82.8%), which was higher than that of a single index, with improved the sensitivity of prediction.

Conclusion:
In patients with AIS, the A2DS2 score combined with NLR is of greater value in predicting the risk of acute ischemic SAP than a single indicator.
Mixed Reality versus Mass or Self-directed Training for Adolescents’ Basic Life Support Instruction: A Prospective, Randomized Pilot Study
Authors: Giacomini Francesco , Querci Lorenzo , Dekel Boaz Gedaliahu Samolsky 
Published: September 2023

Background:
There is limited information about adolescents' Basic-Life-Support (BLS) training.

Objectives:
In this study, adolescents' BLS training proficiency and knowledge retention of the Mixed Reality (MR), Mass-Training (MT), and Self-Directed Learning (SDL) methods were prospectively compared, following the training-outcomes levels-model classification.

Methods:
First-year secondary-school students were randomized into the MR, MT, and SDL groups, and after baseline evaluation, at T0, they received congruent BLS theoretical and Cardiopulmonary-Resuscitation (CPR) training. Knowledge, skills retention, and trainees' training-activity self-evaluation were evaluated utilizing ten (knowledge) and five-items (self-evaluation) questionnaires, a BLS-sequence checklist, and chest compressions recording mannequin one and three months after T0. We used the Kruskal-Wallis test for median comparison.

Results:
At all times, the MR group knowledge answers' median (≥6/10) was significantly higher (p<0.05) than groups MT and SDL (≤6/10), with no significant differences between the latter. The MR CPR skills and BLS checklist acquisition and retention were significantly superior (p<0.05) to the other groups; the SDL group showed limited results. Hands position and chest recoil showed excellent outcomes in all groups and at all times. At all times, trainees positively evaluated the BLS-training importance. Pre-training low self-confidence in BLS practice improved over time, yet not significantly, in group MT. The trainees' majority (62%) preferred the MR method.

Conclusion:
In an adolescent cohort, MR methods' BLS/CPR knowledge and skills acquisition and retention were comparable, if not better, than the MT method and superior to the SDL one. Future multicenter randomized and controlled studies with larger sample sizes and more limited instructor-to-participant ratios are warranted to generalize findings.
Are Combined Techniques using Video Laryngoscopes and Dynamic Stylets Superior to Fiberoptic Techniques for Anticipating Difficult Intubations? A Retrospective Single-center Comparative Analysis
Authors: Shah Ashka R. , Knecht Lauren E. , Durnford Kathyrn M. , Jacobson Cameron , Runnels Sean T. 
Published: September 2023

Introduction:
Studies point to the potential advantages of a combined technique using video laryngoscopes (VL) and dynamic stylets for difficult intubations. This study compares the outcomes of three advanced intubation techniques: combined technique (video laryngoscope + dynamic stylet), awake fiberoptic bronchoscope (FOB), and asleep FOB when used as the primary intubation technique.

Methods:
Airway notes of 138,387 consecutive anesthesia cases at a single academic medical center were filtered for the use of awake FOB, asleep FOB, or combined technique as the primary approach for potentially difficult intubations. The combined technique was defined as VL + dynamic stylet. The dynamic stylets available were FOB or TCITM (Total Control Introducer). The primary endpoint was the first pass success rate. Secondary endpoints included: failure to intubate with the primary technique, anesthesia “in room to intubation” time, “traumatic” intubation rate, and ease of intubation.

Results:
The first pass success rate was highest for combined techniques (88.7%) followed by awake FOB (74.2%, P<0.001) and asleep FOB (80.7%, P=0.06). “Failure to intubate” was lowest in the combined technique (1.8%), compared to awake FOB (9.2%, P=0.002). “In room to intubation” time was fastest for the combined techniques (13.0 minutes) followed by asleep FOB (15.1 minutes, P=0.002) and awake FOB (21.2 minutes, P<0.001). Combined techniques were recorded as “easy” significantly more often (72%) than awake FOB (38.2%, P<0.001). Combined techniques were recorded as “atraumatic” significantly more often (91.1%) than awake FOB (75.8%, P<0.001). Subgroup analysis of the combined techniques, VL + FOB vs. VL + TCITM, revealed that VL + TCITM was rated as “easy” and “atraumatic” significantly more often. It also achieved higher first pass success, lower “failure to intubate” rate, and faster “in room to intubated” time when compared with VL + FOB, although none reached significance.

Conclusion:
In this retrospective single-center comparative analysis, the combined techniques outperformed FOB techniques in effectiveness, speed, ease of use, and trauma.
Comparison of the Frequency of Gastrointestinal Bleeding Complications Resulting from the use of Ketorolac after Gastrointestinal Cancer Surgery with or without Gastric Ulcer Prophylaxis - A Case Control Study
Authors: Kouchek Mehran , Zarei Sadegh , Hosseiniara Reza , Miri MirMohammad 
Published: September 2023

Background:
Gastrointestinal (GI) bleeding after GI cancer surgery is not very common, but the use of NSAIDs such as Ketorolac can aggravate it, and if not controlled properly, it may be life-threatening. Therefore, an NSAID/PPI combination (ketorolac and Pantoprazole) that reduces the adverse effect of ketorolac on GI bleeding can be very important.

Aim:
The aim of this observational study is to compare the frequency of GI bleeding complications resulting from the use of Ketorolac after GI cancer surgery with or without gastric ulcer prophylaxis (Pantoprazole).

Methods:
In this retrospective case-control study, the medical files of adult patients aged 18-60 years undergoing GI cancer surgery referred to 3 hospitals in Iran in 2022 were reviewed. The case group consisted of patients who received ketorolac (30 mg every 8 hours, intravenously) with preventive Pantoprazole (40 mg daily). The control group consisted of patients who only received ketorolac (30 mg every 8 hours, intravenously). Patients were matched in groups based on demographic and clinical variables. Outcomes, including GI bleeding (melena, ...), length of hospital and ICU stay, receiving packed cells, intubation, hematocrit and hemoglobin, were compared between the groups.

Results:
Two groups were matched in terms of age, gender, comorbidities, type of surgery, duration of surgery (hours), and surgical bleeding (ml) (P>0.05). Examination of clinical outcomes showed that GI bleeding complications were not significantly different in the two groups. Although in the case group that received ketorolac and Pantoprazole combination, GI bleeding complications were reported in a smaller number of people. The hospital stay (days) was significantly lower in the case group than in the control group. The ICU stay (hours), packed cells, intubation, hematocrit, and hemoglobin were not significantly different between the two groups.

Conclusion:
The findings of the current study showed that the administration of Pantoprazole plus ketorolac might be effective in controlling bleeding in GI cancer surgery patients, which, of course, requires detailed and multicenter interventional studies.
The Molecular Structural Analysis of Biologically Important Catechol
Molecule: An Integrative Perspective from Experiments and Futuristic
Tools
Authors: Mir M. Amin , Andrews Kim , Ashraf M. Waqar , Kumar Anuj , Kumar Dharmendra , Bisht Anita , Chauhan Reeta , Prakash Shailendra 
Published: September 2023

Background:
Catechol is a phenolic molecule found naturally in plants. It is also known as pyrogallic acid or 1, 2-dihydroxybenzene. Catechol is currently produced commercially by decarboxylating gallic acid at high temperatures and pressures.

Aims and Objectives:
This research aimed to understand the biological importance of catechol and perform molecular structural analysis on catechol molecules.

Methods:
Catechol (1, 2, dihydroxy benzene) was studied via computational analysis by employing the use of DFT and B3LYP methods. Hirshfeld analysis was carried out to investigate crystal intermolecular interactions, and the NBO study was performed to study chemical donating and accepting interactions. Moreover, the computational study was performed using FTIR, HNMR and other instrumentation like AIM theory for circular dichroism data.

Results:
Furthermore, the surface iso-projection study and binding energy results did prove to run in alignment with experimentally obtained values from the computational studies. Fukui functional study and molecular electrostatic potential were utilized in the study to investigate interactions between anionic and cationic sites of catechol. In addition, molecular dynamic simulations revealed that biomolecular stability was also present. Thus, the antibiotic efficacy of catechol displayed chemical oxidative interactions that exhibited close chemical correlations with ascorbic acid, ellagic acid, and gallic acid.

Conclusion:
The catechol has been examined experimentally and theoretically. The results were compared with catechol spectra, including IR and UV-visible spectra generated through computer analysis. The experimentally observed spectra were found to be in parallel with theoretical data. According to drug-likeness investigations, the following compounds, gallic acid, ellagic acid, and ascorbic acid, were found to be closely related to catechol as an antibiotic. Hence, it can be concluded that catechol, whether in its entirety or in a portion, is a potent antibacterial, anti-inflammatory, and anti-malarial drug.