bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Sm core protein SmEb regulates salt stress responses through maintaining proper splicing of RCD1 pre‐mRNA in Arabidopsis
Authors: Hong Yechun , Gao Yang , Pang Jia , Shi Huazhong , Li Tingting , Meng Huiying , Kong Dali , Chen Yunjuan , Zhu Jian‐Kang , Wang Zhen 
Published: January 2023

AbstractSalt stress adversely impacts crop production. Several spliceosome components have been implicated in regulating salt stress responses in plants, however, the underlying molecular basis is still unclear. Here we report that the spliceosomal core protein SmEb is essential to salt tolerance in Arabidopsis. Transcriptome analysis showed that SmEb modulates alternative splicing of hundreds of pre‐mRNAs in plant response to salt stress. Further study revealed that SmEb is crucial in maintaining proper ratio of two RCD1 splicing variants (RCD1.1/RCD1.2) important for salt stress response. In addition, RCD1.1 but not RCD1.2 is able to interact with the stress regulators and attenuates salt‐sensitivity by decreasing salt‐induced cell death in smeb‐1 mutant. Together, our findings uncovered the essential role of SmEb in the regulation of alternative pre‐mRNA splicing in salt stress response.
Narco‐spectrality: Narco‐aesthetics and hauntings in the short filmPánico en Pánuco
Authors: Vizcarra Mael 
Published: January 2023

AbstractThis article uses text and film to demonstrate how the affective and sensory dimensions of narco‐power in contemporary Mexico haunt the familiar. As a case study, I draw on footage documenting my family's trip to Sinaloa to visit my father's birthplace in the rural mining town of Pánuco. Through an analysis of the ghosts produced by the filmmaking process and the disruptions to our travels by an increasingly tangible threat of narco‐violence, this article explores how fear and distrust reshape a pastoral aesthetics of family leisure. Film is adept at exploring sensory, affective, and embodied aspects of everyday experience. Here it is used to evoke unfolding tensions among my family members, underlining the ways narco‐terror manifests atmospherically and as an embodied experience. Film and text here narrate a subjective experience of narco‐power and make the case for the ways a spectral narco‐aesthetics, or narco‐spectrality, permeate the familiar.
Response Bias in Survey Measures of Expectations: Evidence from the Survey of Consumer Expectations’ Inflation Module
Authors: Comerford David A. 
Published: January 2023

AbstractThe Survey of Consumer Expectations (SCE) infers respondents’ inflation expectations from density forecasts. Using numeracy data and tests for coherence among 117,000 respondents to the SCE, I find that density forecasts suffer non‐negligible reporting bias and selective nonresponse. A simple verbal question collected by the SCE suffers neither of these deficiencies and so has better properties to deliver an accurate snapshot of the population's inflation expectations than the headline measures of inflation expectations published by the SCE. I demonstrate how the verbal measure can be harnessed to improve the signal‐to‐noise ratio in density forecasts.
Hericerin derivatives activates a pan‐neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
Authors: Martínez‐Mármol Ramón , Chai YeJin , Conroy Jacinta N. , Khan Zahra , Hong Seong‐Min , Kim Seon Beom , Gormal Rachel S. , Lee Dae Hee , Lee Jae Kang , Coulson Elizabeth J. , Lee Mi Kyeong , Kim Sun Yeou , Meunier Frédéric A. 
Published: January 2023

AbstractThe traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons. N‐de phenylethyl isohericerin (NDPIH), an isoindoline compound from this mushroom, together with its hydrophobic derivative hericene A, were highly potent in promoting extensive axon outgrowth and neurite branching in cultured hippocampal neurons even in the absence of serum, demonstrating potent neurotrophic activity. Pharmacological inhibition of tropomyosin receptor kinase B (TrkB) by ANA‐12 only partly prevented the NDPIH‐induced neurotrophic activity, suggesting a potential link with BDNF signaling. However, we found that NDPIH activated ERK1/2 signaling in the absence of TrkB in HEK‐293T cells, an effect that was not sensitive to ANA‐12 in the presence of TrkB. Our results demonstrate that NDPIH acts via a complementary neurotrophic pathway independent of TrkB with converging downstream ERK1/2 activation. Mice fed with H. erinaceus crude extract and hericene A also exhibited increased neurotrophin expression and downstream signaling, resulting in significantly enhanced hippocampal memory. Hericene A therefore acts through a novel pan‐neurotrophic signaling pathway, leading to improved cognitive performance.image
Efficacy of ferric carboxymaltose for treatment of iron deficiency anemia diagnosed in the third trimester of pregnancy: A case–control study
Authors: Busnelli Andrea , Fabiani Chiara , Acerboni Stefano , Moretti Montefusco Sarah , Di Simone Nicoletta , Setti Paolo Emanuele Levi , Bulfoni Alessandro 
Published: January 2023

AbstractAimTo assess the efficacy of intravenous ferric carboxymaltose (IV FCM) for the treatment of iron deficiency anemia (IDA) diagnosed de novo in the third trimester of pregnancy.MethodsCase–control study conducted in pregnant women with IDA newly diagnosed in the third trimester of pregnancy. Women treated with a single IV FCM injection were included as cases and those who received daily 210 g of oral ferrous sulphate (FS) as controls. Controls were matched to cases in a 2:1 ratio by basal hemoglobin (Hb) concentration (±0.5 g/dl).ResultsA total of 35 cases and 70 controls were included in the study. The mean Hb concentration level significantly increased after iron treatment in both cases (from 9.3 ± 0.8 to 11.1 ± 0.8 g/dl, p < 0.0001) and controls (from 9.6 ± 0.9 to 10.9 ± 1 g/dl, p < 0.0001). The rate of women who exceeded the recommended threshold of 11 g/dl after treatment did not significantly differ between cases (63% (95%CI, 45%–79%)) and controls (56% (95%CI, 44%–68%)) (p = 0.48). Comparison of maternal and neonatal outcomes and adverse effects did not show any significant difference between groups.ConclusionsOur results suggest that IV FCM and oral FS can be considered equally effective in the treatment of IDA newly detected in the third trimester of pregnancy.
Do people diagnosed with psychosis spectrum disorders share the same personality space as the general population? Big Five complemented by the proneness to psychotic‐like experiences/behaviors
Authors: Ristić Ivan , Knežević Goran , Ristić Dragana Ignjatović , Miljević Čedo , Jerotić Stefan , Marić Nađa P. 
Published: January 2023

AbstractObjectiveDisintegration is a recently proposed broad, trait‐like reconceptualization of the proneness to psychotic‐like experiences/behaviors.MethodsWe tested the assumption that the 6‐factor model (Five‐Factor traits plus Disintegration) was the most adequate one and that it was invariant across clinical and non‐clinical populations. The clinical sample (n = 161) consisted of patients who had at least one psychotic episode, duration of illness less than 10 years, currently in remission. The general population (n = 409) was matched with the patient sample by age, gender, and education. NEO PI‐R and DELTA were used to measure personality dimensions in both samples. Invariance of one to six‐factor solutions was tested by Exploratory Structural Equation Modeling.ResultsWe found that: (a) several criteria for deciding on the number of factors to retain converged to the conclusion that the assumed 6‐factor model was the most adequate one, (b) the assumed factorial structure appeared to satisfy the criteria for the scalar invariance across the two samples, (c) all nine Disintegration subdimensions separated from the Big Five, forming the Disintegration factor, and (d) Disintegration was unrelated to Openness.ConclusionThe Big Five personality structure—complemented with disintegration—was invariant across individuals from the general population and patients with psychosis.
Employer risk‐adjustment transitions with inertial consumers: Evidence from CalPERS
Authors: Handel Benjamin , Hong Nianyi , Hua Lynn M. , Ito Yuki 
Published: January 2023

AbstractRisk‐adjustment policies, which transfer money from insurers with healthy consumers to those with sick consumers, are an important tool to contend with adverse selection in health insurance markets. While the steady‐state properties of risk‐adjustment have been studied extensively, there is less evidence on the transition phase of policy implementation. We study the introduction and removal of risk‐adjustment at California Public Employees' Retirement System and show that these changes meaningfully impact premiums via plan differences in enrollee health status. Despite these premium differences, there is limited consumer resorting due to consumer inertia, though new active enrollees respond more fluidly. We show that, with inertial consumers, risk‐adjustment changes have substantial distributional consequences, leading to worse outcomes for sicker consumers when removed and vice‐versa when implemented. We estimate a model of plan choice with premium sensitivity, brand preferences, and inertia and use these estimates to study the interaction between risk‐adjustment policies and the strength of inertia.
Research‐practice partnerships: Adapting a care coordination intervention for rural Veterans over 3 years at multiple sites
Authors: Zullig Leah L. , Lewinski Allison A. , Woolson Sandra L. , White‐Clark Courtney , Miller Christopher , Bosworth Hayden B. , Burleson Stephanie C. , Garrett Mary P. , Darling Kristen L. , Crowley Matthew J. 
Published: January 2023

AbstractPurposeRural Veterans are more likely than urban Veterans to qualify for community care (Veterans Health Administration [VHA]‐paid care delivered outside of VHA) due to wait times ≥30 days and longer travel times for VHA care. For rural Veterans receiving both VHA and community care, suboptimal care coordination between VHA and community providers can result in poor follow‐up and care fragmentation. We developed Telehealth‐based Coordination of Non‐VHA Care (TECNO Care) to address this problem.MethodsWe iteratively developed and adapted TECNO Care with partners from the VHA Office of Rural Health and site‐based Home Telehealth Care in the Community programs. Using templated electronic health record notes, Home Telehealth nurses contacted Veterans monthly to facilitate communication with VHA/community providers, coordinate referrals, reconcile medications, and follow up on acute episodes. We evaluated TECNO Care using a patient‐level, pre‐post effectiveness assessment and rapid qualitative analysis with individual interviews of Veterans and VHA collaborators. Our primary effectiveness outcome was a validated care coordination quality measure. We calculated mean change scores for each care continuity domain.FindingsBetween March 2019 and October 2021, 83 Veterans received TECNO Care. Veterans were predominately White (86.4%) and male (88.6%) with mean age 71.4 years (SD 10.4). Quantitative data demonstrated improvements in perceived care coordination following TECNO Care in 7 categories. Qualitative interviews indicated that Veterans and Home Telehealth nurses perceived TECNO Care as beneficial and addressing an area of high need.ConclusionsTECNO Care appeared to improve the coordination of VHA and community care and was valued by Veterans.
Autoregressive conditional proportion: A multiplicative‐error model for (0,1)‐valued time series
Authors: Aknouche Abdelhakim , Dimitrakopoulos Stefanos 
Published: January 2023

We propose a multiplicative autoregressive conditional proportion (ARCP) model for (0,1)‐valued time series, in the spirit of GARCH (generalized autoregressive conditional heteroscedastic) and ACD (autoregressive conditional duration) models. In particular, our underlying process is defined as the product of a (0,1)‐valued independent and identically distributed (i.i.d.) sequence and the inverted conditional mean, which, in turn, depends on past reciprocal observations in such a way that is larger than unity. The probability structure of the model is studied in the context of the stochastic recurrence equation theory, while estimation of the model parameters is performed with the exponential quasi‐maximum likelihood estimator (EQMLE). The consistency and asymptotic normality of the EQMLE are both established under general regularity assumptions. Finally, the usefulness of our proposed model is illustrated with two real datasets.
Bottom‐up and top‐down control of seagrass overgrazing by the sea urchin Tripneustes gratilla
Authors: Moreira‐Saporiti Agustín , Hoeijmakers Dieuwke , Reuter Hauke , Msuya Flower E. , Gese Katrin , Teichberg Mirta 
Published: January 2023

AbstractThe lack of top‐down control on Tripneustes gratilla, a sea urchin commonly known to graze on seagrass, and the bottom‐up control of its feeding preference, led to the overgrazing of seagrass meadows of the species Thalassodendron ciliatum in Changuu Island (Zanzibar Archipelago). The impact of overgrazing on seagrasses was assessed by mapping the presence of grazed versus non‐grazed seagrass patches in the study site, while the top‐down control on T. gratilla was assessed by measuring the abundance of its fish predators. The feeding preference and distribution of T. gratilla were characterized by calculating the electivity indexes for each seagrass species and measuring sea urchin density, respectively. Approximately half of the patches of T. ciliatum were overgrazed, while predatory fishes of T. gratilla were absent from the site. The Vanderploeg and Scavia's Relativized Electivity Index indicated that T. gratilla had a feeding preference for T. ciliatum, which was also supported by higher urchin densities within T. ciliatum dominated patches. Bottom‐up control of grazing activity was observed by quantifying and analyzing morphological, nutritional, and the chemical defense traits of the seagrass in relation to feeding preference and urchin density. Feeding was positively correlated to the seagrass tissue C:P ratio (ρ = 0.9), whereas urchin density showed no correlations. The bottom‐up control of the feeding preference and agglomeration of T. gratilla in T. ciliatum meadows, together with the lack of evidence of substantial top‐down control and the long recovery time of T. ciliatum led to the overgrazing of this species at this site. Overgrazing, therefore, was shown to be the result of multiple factors ranging from the traits of the seagrass and feeding preference of T. gratilla, to the abundance of predators in this area.
Does baseline EEG activity differ in the transition to or from a chronic pain state? A longitudinal study
Authors: Schuurman Britt B. , Vossen Catherine J. , van Amelsvoort Therese A. M. J. , Lousberg Richel L. 
Published: January 2023

AbstractBackground and AimIdentifying EEG brain markers might yield better mechanistic insights into how chronic pain develops and could be treated. An existing longitudinal EEG study gave us the opportunity to determine whether the development of pain is accompanied by less alpha power—ie, a “relaxed” brain state—and vice versa.MethodsFive‐minute resting EEG with the eyes open was measured 2 times in 95 subjects at T0 (baseline) and T1 (6 months later). Based on the Short‐Form Health Survey and Brief Pain Inventory questionnaire, subjects were divided into 4 groups: staying pain‐free (n = 44), developing chronic pain (n = 8), becoming pain‐free (n = 15), and ongoing chronic pain (n = 28). The EEG data of 14 electrodes were analyzed by multilevel regression.ResultsThe group that developed chronic pain demonstrated less power in the lower‐frequency bands over time during the resting state EEG, whereas the transition to a pain‐free state had the opposite pattern. Thus, the a priori hypothesis was confirmed.ConclusionsTransitions in pain states are linked to a change in baseline EEG activity. Future research is needed to replicate these results in a larger study sample and in targeted clinical populations. Furthermore, these results might be beneficial in optimizing neurofeedback algorithms for the treatment of chronic pain.
Genetic loci and candidate genes with pleiotropic effects for tofu and soymilk weights across multiple environments in soybean (Glycine max)
Authors: Huang Meihong , Chen Shiliang , Li Wenlong , Tian Rui , Zhang Hua , Shao Zhenqi , Li Xihuan , Zhang Caiying 
Published: January 2023

AbstractSoybean provides large amounts of protein for human, and the most popular consumption pattern is tofu and soymilk. Recently, the demand of tofu and soymilk is increased, and the breeding of special variety becomes very urgent. To illustrate the genetic basis of these traits, 269 accessions were evaluated under six environments, and 32 associated SNPs were identified on nine chromosomes across multiple environments or conferring diverse traits. Of these SNPs, 16 were demonstrated by BLUP values. Seven adjacent‐SNPs were first identified to associate with tofu and soymilk weights in an 1.02‐Mb region on chromosome 8, which were verified by BLUP‐values. Meanwhile, four neighbouring SNPs in a 0.32‐Mb region on chromosome 12 were first identified to associate with these traits across multiple environments, of which three were detected in BLUP values. Furthermore, some candidate genes, that is, α‐glucan water dikinase Glyma.08G283700 and E3 SUMO‐protein ligase Glyma.12G071300, were screened out with differential expressions between the high‐ and low‐tofu/soymilk‐output accessions. Thus, these associated SNPs and candidate genes provide new insight into the genetic basis of tofu and soymilk processing quality in soybean.
Effect of self‐constructed concept map with peer feedback on chemistry learning outcome
Authors: Oni Oluwasola S. , Adesope Olusola O. , Wong Rachel , Nishida Krista 
Published: January 2023

AbstractConcept mapping remains widely used in education. However, little is known about how self‐constructed concept maps and peer feedback can improve student learning outcomes in chemistry. We investigated the effects of peer feedback on concept mapping and how it improves students' learning performance in a large second‐semester, introductory chemistry course. Three hundred and twenty students were randomly assigned to one of two concept mapping conditions: self‐constructed concept map with peer feedback and self‐constructed concept map without peer feedback. Each group constructed concept maps that depicted the relationship between concepts on the topic of intermolecular force. The results showed that students in the self‐constructed concept map with peer feedback condition outperformed students in the no peer feedback condition in chemistry learning outcome. Overall, this study demonstrates that peer feedback enhances the effectiveness of learning with generative concept maps. The implications and future directions are discussed.
MRI features can help to confirm a diagnosis of progressive myelomalacia, but may not be accurate in dogs lacking characteristic clinical signs at the time of imaging
Authors: Cordle Katelyn J. , Seiler Gabriela S. , Barnes Danielle , Olby Natasha J. 
Published: January 2023

AbstractProgressive myelomalacia (PMM) is a fatal sequela of acute thoracolumbar intervertebral disc extrusion in dogs, with unpredictable onset in the days after the inciting injury. No single reliable diagnostic test is currently available. Magnetic resonance imaging (MRI) features such as T2‐weighted spinal cord hyperintensity and loss of subarachnoid signal in a half‐Fourier single‐shot turbo spin echo (HASTE) sequence have been associated with PMM, but are sometimes present in other dogs with severe deficits. Magnetic resonance imaging findings in 22 dogs with a clinical or histopathologic diagnosis of PMM and 38 deep pain‐negative paraplegic dogs were compared in a retrospective case‐control study. Length of T2‐weighted hyperintense spinal cord change and HASTE signal loss were significantly associated with clinically evident PMM (P = .0019 and P = .0085), however, there were no significant differences between groups when analysis was restricted to dogs not yet showing clinical signs of PMM. The PMM group also had significantly shorter compressive lesions than the control group (P = 0.026), suggesting a possible role of more severe focal pressure at the extrusion site. A segment of total loss of contrast enhancement in the venous sinuses and meninges, a feature not previously described, was more common in the PMM group and the difference approached significance (P = 0.054). Findings show that MRI features can support the diagnosis in dogs with clinical evidence of PMM, and absence of these features supports absence of PMM at time of imaging. However, their absence does not reliably differentiate dogs with imminent progressive myelomalacia from other dogs with severe deficits following intervertebral disc extrusion.
Study of Sooting Propensity and Related Indices Based on Tests With Isolated Droplets
Authors: Muelas Álvaro , Sanz Sofía , Ballester Javier 
Published: January 2023

Abstract
This work compares two approaches to characterize the sooting propensity of liquid fuels, namely, the Threshold Soot Index (TSI) obtained from smoke point measurements and the Isolated Droplet Soot Yield (IDSY), an original metric expressing the mass of soot collected from single droplets vaporizing under a hot atmosphere representative of conventional flames. The TSI of different fuels was experimentally obtained by means of a computer-vision method, whereas their IDSY was extracted using a free-falling droplet combustion facility. The results clearly pointed to a linear dependency of the IDSY with mass fraction, allowing to propose a mixture rule for this index for a significantly broader measuring range than that allowed by the smoke point lamp. A nonlinear correlation was found between IDSY and TSI, with relevant deviations for some compounds. These deviations could advise to consider which of the available indices (TSI, IDSY, others) would be more adequate to emulate the sooting behavior.
The Socioeconomic Paradox of Physical Activity and Sedentary Behavior in Europe
Authors: Moreno-Llamas Antonio , García-Mayor Jesús , De la Cruz-Sánchez Ernesto 
Published: January 2023

Background: A low socioeconomic status (SES) presents lower physical activity; however, the relationship between SES and sedentary behavior (SB) remains unclear. We aimed to assess this association of SES with physical activity (PA) and SB. Methods: We employed representative self-reported data of the European Union from the cross-sectional survey Eurobarometer 2017, comprising a final sample of 13,708 citizens (18–64 y old), to assess the association of SES (education, occupation, and economic issues) with PA and sitting time quartiles, and to describe inequalities in vigorous, moderate, and walking activity and sitting time. Results: Multinomial regressions revealed that people from higher SESs were more likely to report higher PA; nonetheless, higher educational attainment and occupations were also associated with higher sitting time but not with lower economic issues. The inequality, shown by Gini coefficients, describes a socioeconomic gradient in vigorous and moderate activity, from higher inequality in lower statuses to lower inequality in higher statuses. The Gini coefficients also indicated higher socioeconomic inequalities in PA than SB. Conclusions: Higher SESs showed paradoxically more PA and SB; however, sitting time presented smaller differences and a more homogeneous distribution across the population.