bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward the internet of things forensics: A data analytics perspective
Authors: Khanpara Pimal , Shah Ishwa , Tanwar Sudeep , Verma Amit , Sharma Ravi 
Published: March 2023

AbstractThe widespread use of networked, intelligent, and adaptable devices in various domains, such as smart cities and home automation, climate control, manufacturing and logistics, healthcare, education, and agriculture, has been hastened by recent developments in hardware and software technologies. In all these application domains, the concept of the Internet of Things helps to achieve process automation and decrease labor costs. While IoT has been an established domain for quite a while, it has seen a lot of advances and challenges in different subdomains over the years. One such subdomain is IoT Forensics which involves digital forensics concerning IoT devices, networks, or clouds. In this process of obtaining substantial evidence from the devices, networks, or cloud, a large amount of data and operations on said data are involved. Hence, looking through IoT Forensics through the methodology dealing with data, known as data analytics, is essential. This paper presents an interpretation of IoT Forensics from the standpoint of data analytics. To explain the same in detail, the paper focuses on IoT Forensics, its methodologies, and how they relate to data analytics stages. Toward the end, the paper discusses current developments in IoT Forensics from the data analytics perspective, limitations observed in the existing technologies, adoption challenges, and possible future advancements.
A reading of Alexander Bogdanov in times of crisis
Authors: Rendon‐Sanchez Juan F. 
Published: March 2023

AbstractReading Bogdanov today can surprise us with the relevance of his work, the coincidence of some of his ideas with contemporary thought and the productivity of his approaches. Systems thinking, with its capacity to engage with diverse areas, including science and philosophy, is an appropriate avenue for approaching some of our present global problems. I attempt in this article to highlight key ideas and observations from Bogdanov along a line demarcated by some critical thinkers including G. K Chesterton and S. Žižek. This dialogue can illuminate useful paths in our times of crisis: I highlight some commonalities in the organisational tendency urgently suggested by our circumstances and proposed in different manners; I then propose to rekindle the idea of scientific organisation of experience and the formulation of some questions around our dynamic equilibrium/disequilibrium with nature, by using Tektology concepts. Lastly I pose the case for systematically studying human excess.
A survey on what users think about SysML
Authors: Santos Tauany L. S. , Soares Michel S. 
Published: March 2023

AbstractSystems Modeling Language (SysML) has been applied in the past years to a variety of software and systems engineering projects, by hundreds of researchers, engineers, and other systems and software professionals. Thus, it is expected that all this experience has been described in research articles. Therefore, we propose a survey describing what practitioners and researchers think about this modeling language, the actual use of SysML, and how SysML is used in the software and system engineering life cycle. This article describes a survey on SysML, answering questions such as the most used diagrams for each phase of the development of a system, the most common domains, and other data about the participants. The survey was answered by 343 participants from 38 countries, mostly systems engineers, software and systems architects, and researchers. Industry and academia can use our results (i) for assisting researchers and engineers to select appropriate diagrams for each software and systems development phase, (ii) for a better understanding of which industry domains SysML is most commonly applied, (iii) as a reference for identifying which types of systems are modeled with SysML, (iv) for knowing which software tools are most used, and (v) which other modeling languages are most commonly integrated with SysML for software and systems development.
Testing coverage‐based software reliability growth model considering uncertainty of operating environment
Authors: Pradhan Vishal , Dhar Joydip , Kumar Ajay 
Published: March 2023

AbstractSoftware reliability is one of the standard critical inherent characteristics of software systems. The testing coverage function (TCF) is a significant parameter for identifying the completeness and effectiveness of software testing. It is defined as the proportion of the code that has been tested up to timet. To capture the dynamic behavior of the number of faults detected over a period of time, several distributions, namely S‐shaped, inflection S‐shaped, logistic, log‐logistic, Weibull, Rayleigh, Erlang, and logarithmic exponentiated, have been used as TCF in literature. However, these distributions are not sufficient to describe TCF's practical behavior due to complexity and vagueness in the collected data. This study proposes two software reliability growth models (SRGMs), which incorporate the generalized inflection S‐shaped (GISS) distribution as TCF. The models have been developed in perfect and imperfect debugging environments while considering fault removal efficiency, error generation, and uncertainty in the operating environment. To analyze the effectiveness, the proposed models are then tested with six failure data sets. The choice of GISS distribution as a TCF improves the software reliability estimation in comparison with the existing models in the literature. Finally, single and multiple parameters sensitivity analysis also has been done and based on it, the critical parameters have been detected. The proposed models may be helpful for the system analyst to predict various parameters about some software systems.
The challenges of classifying big genera such asIpomoea
Authors: Muñoz‐Rodríguez Pablo , Wood John R.I. , Wells Tom , Carruthers Tom , Sumadijaya Alex , Scotland Robert W. 
Published: March 2023

AbstractBig genera represent a significant proportion of the world's plants. However, comprehensive taxonomic and evolutionary studies of these genera are often complicated by their size and geographic spread. This paper explores the challenges faced in classifying these megadiverse plant groups consequent to the existing tension between diagnosability and increasing levels of resolution from molecular sequence data. We use recent examples from across angiosperms to illustrate how monophyly, diagnosability and completeness interplay with each other in attempts to classify several big genera and, specifically, the genusIpomoea(Convolvulaceae).Ipomoeaand the tribe Ipomoeeae have been the object of recent taxonomic and phylogenetic studies that highlight the limitations of previous attempts to classify the group, and show that the smaller segregate genera traditionally recognised in Ipomoeeae are nested withinIpomoeaand are neither monophyletic nor diagnosable. We argue that existing classifications must be abandoned, and that recognising an expandedIpomoeathat incorporates all segregate genera of the Ipomoeeae is the most appropriate solution as it reconciles the properties of monophyly, diagnosability and completeness, and favours nomenclatural stability.
Institutional networks in cooperative population management: Exploring patterns in transfer fulfillment
Authors: Gray Steven M. , Parsons Arielle W. , Andrews John E. , Schad Eebes Kristine , Faust Lisa J. , Che‐Castaldo Judy 
Published: March 2023

AbstractLong‐term sustainability of ex‐situ animal populations is important for zoos and aquariums, but challenging due to inconsistent compliance with Breeding and Transfer Plans. Transfer recommendations are key to promoting the sustainability of ex‐situ animal populations by ensuring cohesive populations, genetic diversity, and demographic stability, but factors affecting their fulfillment are poorly understood. We used a network analysis framework to analyze data compiled from PMCTrack from 2011 to 2019 for three taxonomic classes (mammals, birds, and reptiles/amphibians) within the Association of Zoos and Aquariums to assess factors affecting transfer recommendation fulfillment. Of 2505 compiled transfer recommendations spanning 330 Species Survival Plan® (SSP) Programs and 156 institutions, 1628 (65%) of them were fulfilled. Transfers were most likely to be fulfilled between institutions in close proximity with an established relationship. Annual operating budget, SSP Coordinator experience, number of staff, and diversity of Taxonomic Advisory Groups in which an institution participates also influenced transfer recommendations and/or fulfillment, but effects varied with taxonomic class. Our results suggest that current practices of focusing on transfers between institutions in close proximity are working to maximize transfer success and that institutions with larger budgets and some degree of taxonomic specialization play important roles in promoting success. Success could be further enhanced by building reciprocal transfer relationships and encouraging further development of relationships between smaller institutions and larger ones. These results emphasize the utility of examining animal transfers using a network approach, which accounts for attributes of both sending and receiving institutions, describing novel patterns otherwise left undetected.
Systematic analysis of the pharmacological content of the Tatort (scene of crime) TV series from 2019 to 2021
Authors: Borchert Marcel , Seifert Roland 
Published: March 2023

AbstractTatort (scene of crime) is a must-see programme on Sunday evenings for many Germans. With its enormous reach, the crime series also deals in more than half of its episodes with active pharmacological substances, surprisingly most of them are used curatively. There are lots of ways representing the active pharmacological substances: simply naming the preparation to details such as information on how to take it or how it is manufactured illegally. Diseases of great interest to the public such as hypertension or depression are taken up. In addition to the correct presentation, in 20% of cases the active pharmacological substances were presented incorrectly or implausibly. But even with correct presentation, it may yield a harmful influence on viewers: Stigmatisation of preparations occurred in 14%, especially in the case of active pharmacological substances that are used in psychiatric therapies; presentations that could be considered dangerous occurred in 21% of the mentions. In 29%, content was presented positively to the audience beyond the correct presentation. Analgesics and active pharmacological substances used in psychiatry are frequently titled. But drugs such as amiodarone, insulin or "cortisone" are also mentioned. The potential for misuse is also presented. Tatort also educates the audience about common diseases and their treatment, for example hypertension, depression or the use of antibacterial drugs. However, the series does not educate the general public on the mechanism of action of commonly used drugs. There is a natural dilemma between informing the public and guiding them to misuse medicines. Finally, we discuss how future episodes could be improved with respect to pharmacological content.
Non-target estrogenic screening of 60 pesticides, six plant protection products, and tomato, grape, and wine samples by planar chromatography combined with the planar yeast estrogen screen bioassay
Authors: Mehl Annabel , Seiferling Sophia , Morlock Gertrud E. 
Published: March 2023

AbstractFor non-target residue analysis of xenoestrogens in food, sophisticated chromatographic–mass spectrometric techniques lack in biological effect detection. Various in vitro assays providing sum values encounter problems when opposing signals are present in a complex sample. Due to physicochemical signal reduction, cytotoxic or antagonistic effect responses, the resulting sum value is falsified. Instead, the demonstrated non-target estrogenic screening with an integrated planar chromatographic separation differentiated opposing signals, detected and prioritized important estrogenic compounds, and directly assigned tentatively the responsible compounds. Sixty pesticides were investigated, ten of which showed estrogenic effects. Exemplarily, half-maximal effective concentrations and 17β-estradiol equivalents were determined. Estrogenic pesticide responses were confirmed in six tested plant protection products. In food, such as tomato, grape, and wine, several compounds with an estrogenic effect were detected. It showed that rinsing with water was not sufficient to remove selected residues and illustrated that, though not usually performed for tomatoes, peeling would be more appropriate. Though not in the focus, reaction or breakdown products that are estrogenic were detected, underlining the great potential of non-target planar chromatographic bioassay screening for food safety and food control.
Graphical Abstract
Natural deep eutectic solvent-based microextraction for mercury speciation in water samples
Authors: Ripoll Laura , Rayos Javier , Aguirre Miguel Ángel , Vidal Lorena , Canals Antonio 
Published: March 2023

AbstractA new natural deep eutectic solvent (NADES)-based analytical method for mercury speciation in water samples is presented. A NADES (i.e., decanoic acid:DL-menthol in a molar ratio of 1:2) is used as an environmentally friendly extractant for separation and preconcentration using dispersive liquid–liquid microextraction before LC-UV–Vis. Under optimal extraction conditions (i.e., NADES volume, 50 µL; sample pH, 12; volume of the complexing agent, 100 µL; extraction time, 3 min; centrifugation speed, 3000 rpm; and centrifugation time, 3 min), the limit of detection values were 0.9 µg L−1 for the organomercurial species and 3 µg L−1 for Hg2+, which had a slightly higher value. The relative standard deviation (RSD, n = 6) has been evaluated at two concentration levels (25 and 50 µg L−1) obtaining values for all the mercury complexes within the range of 6–12% and 8–12%, respectively. The trueness of the methodology has been evaluated using five real water samples from four different sources (i.e., tap, river, lake, and wastewater). The recovery tests have been performed in triplicate obtaining relative recoveries between 75 and 118%, with RSD (n = 3) between 1 and 19%, for all the mercury complexes in surface water samples. However, wastewater sample showed a significant matrix effect (recoveries ranged between 45 and 110%), probably due to the high amount of organic matter. Finally, the greenness of the method has also been evaluated by the analytical greenness metric for sample preparation (i.e., AGREEprep).
Graphical Abstract
Effect of digoxin on all-cause and cardiovascular mortality in patients with atrial fibrillation with and without heart failure: an umbrella review of systematic reviews and 12 meta-analyses
Authors: Gazzaniga Gianluca , Menichelli Danilo , Scaglione Francesco , Farcomeni Alessio , Pani Arianna , Pastori Daniele 
Published: March 2023

Abstract
Purpose
To perform a systematic umbrella review with meta-analysis to evaluate the certainty of evidence on mortality risk associated with digoxin use in patients with atrial fibrillation (AF) with or without heart failure (HF).

Methods
We systematically searched MEDLINE, Embase, and Web of Science databases from inception to 19 October 2021. We included systematic reviews and meta-analyses of observational studies investigating digoxin effects on mortality of adult patients with AF and/or HF. The primary outcome was all-cause mortality; secondary outcome was cardiovascular mortality. Certainty of evidence was evaluated by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool and the quality of systematic reviews/meta-analyses by the A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR2) tool.

Results
Eleven studies accounting for 12 meta-analyses were included with a total of 4,586,515 patients. AMSTAR2 analysis showed a high quality in 1, moderate in 5, low in 2, and critically low in 3 studies. Digoxin was associated with an increased all-cause mortality (hazard ratio [HR] 1.19, 95% confidence interval [95%CI] 1.14–1.25) with moderate certainty of evidence and with an increased cardiovascular mortality (HR 1.19, 95%CI 1.06–1.33) with moderate certainty of evidence. Subgroup analysis showed that digoxin was associated with all-cause mortality both in patients with AF alone (HR 1.23, 95%CI 1.19–1.28) and in those with AF and HF (HR 1.14, 95%CI 1.12–1.16).

Conclusion
Data from this umbrella review suggests that digoxin use is associated with a moderate increased risk of all-cause and cardiovascular mortality in AF patients regardless of the presence of HF.

Trial registration
This review was registered in PROSPERO (CRD42022325321).
Can colony resizing represent a strategy for octocorals to face climate warming? The case of the precious red coral Corallium rubrum
Authors: Roveta Camilla , Pulido Mantas Torcuato , Bierwirth Jan , Calcinai Barbara , Coppari Martina , Di Camillo Cristina Gioia , Puce Stefania , Villechanoux Juliette , Cerrano Carlo 
Published: March 2023

AbstractModular colonial benthic organisms exhibit high phenotypic plasticity, which is considered an effective strategy when faced with fluctuations in abiotic and biotic factors. However, when environmental changes occur abruptly, organisms’ adaptive capabilities can be limited, leading to the death of some colonies or to mass mortalities. Additionally, a decrease in body size has been proposed as one of the most common responses in both terrestrial and aquatic organisms to face global warming. Here, temperate corals’ response to thermal stress was documented using the precious red coral Corallium rubrum as a model species. The increased frequency of marine heat waves recorded in the north-western Mediterranean has led to a decrease in the total number of colonies of the analysed populations and reduced colony size in those that have survived, likely through fragmentation and branch loss. The laboratory analyses carried out on collected fragments showed an unexpected swelling, similar to resorption. Additionally, the occurrence of regular sclerite-like protuberances, typical of a normal skeleton surface, suggested a regeneration process. The documented phenomenon supports the hypothesis that C. rubrum exhibits an adaptive behaviour via the autotomy of branches, providing it with an unexpected resilience against climate anomalies thanks to phenotypic plasticity.
The Odd Chromatic Number of a Planar Graph is at Most 8
Authors: Petr Jan , Portier Julien 
Published: March 2023

AbstractPetruševski and Škrekovski recently introduced the notion of an odd colouring of a graph: a proper vertex colouring of a graph G is said to be odd if for each non-isolated vertex $$x \in V(G)$$

x
∈
V
(
G
)

there exists a colour c appearing an odd number of times in its neighbourhood N(x). Petruševski and Škrekovski proved that for any planar graph G there is an odd colouring using at most 9 colours and, together with Caro, showed that 8 colours are enough for a significant family of planar graphs. We show that 8 colours suffice for all planar graphs.
Back to the future: breast surgery with tumescent local anesthesia (TLA)?
Authors: Boeer B. , Helms G. , Pasternak J. , Roehm C. , Kofler L. , Haefner H. M. , Moehrle M. , Heim E. , Fischer H. , Brucker S. Y. , Hahn M. 
Published: March 2023

Abstract
Purpose
Breast surgery is usually performed under general anesthesia. Tumescent local anesthesia (TLA) offers the possibility to anesthetize large areas with highly diluted local anesthetic.

Methods
In this paper, the implementation, and experiences with TLA in the field of breast surgery are discussed.

Conclusion
For carefully selected indications, breast surgery in TLA represents an alternative to ITN.
Clinico-histopathological review of 255 patients who underwent parotidectomy for pleomorphic adenoma: a 10-year retrospective study—a proposal for an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma
Authors: Zoccali Federica , Cialente Fabrizio , Colizza Andrea , Ralli Massimo , Greco Antonio , de Vincentiis Marco 
Published: March 2023

Abstract
Purpose
Pleomorphic adenoma (mixed tumor) is the most common neoplasm of the parotid gland and one of the most frequent types of salivary gland tumor, generally with benign behavior and relatively slow growing. The adenomas could arise from the superficial, deep or from both superficial and deep parotid’s lobes.

Methods
The aim of this review is to retrospectively analyze the surgical management of patients with pleomorphic adenoma of the parotid gland performed at the Department of Otorhinolaryngology (Department of Sense Organs of “Azienda Policlinico Umberto I” in Rome), from 2010 to 2020, with a focus on the percentage of recurrence and on the complication related to surgery to suggest an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma. The analysis of the complications observed in case of different surgical approaches was performed using the X2 test.

Results
The choice of a surgical approach (superficial parotidectomy—SP, total parotidectomy—TP, extracapsular dissection—ECD) depends on several elements, such as the location and the size of the adenoma, the availability of existing technical facilities and the professional experience of the surgeon. A transient facial palsy was present in 37.6%, 2.7% reported a permanent facial nerve palsy, 1.6% developed a salivary fistula, 1.6% a post-operative bleeding and 2.3% showed Frey Syndrome.

Conclusion
The surgical management of this benign lesion is required, even in asymptomatic cases, to prevent the progressive growing and to reduce the risk of malignant transformation. The goal of surgical excision is to obtain the complete resection to minimize the risk of tumor recurrence and avoiding facial nerve disability. Therefore, an accurate preoperative study of the lesion and the choice of the most appropriate surgical treatment are essential to minimize the rate of recurrence.
Circadian rhythmicity in schizophrenia male patients with and without substance use disorder comorbidity
Authors: Adan Ana , Marquez-Arrico Julia E. , Río-Martínez Laura , Navarro José Francisco , Martinez-Nicolas Antonio 
Published: March 2023

AbstractCircadian rhythmicity is associated to clinical variables that play an important role in both schizophrenia (SZ) and substance use disorders (SUD), although the characteristics of the coexistence of these two diagnoses (SZ +) remain mostly unknown. Hence, we studied a sample of 165 male patients divided in three groups each of 55, according to their diagnoses (SZ + , SZ, and SUD), as well as a healthy control (HC; n = 90) group. Alongside with sociodemographic and clinical variables, circadian rhythms were registered through a sleep–wake data structured interview, a circadian typology questionnaire, and distal skin temperature (DST) using the Thermochron iButton every 2 min during 48 h. Analyses showed that SZ + and SZ patients presented a longer sleep (delay in wake-up time) and mostly an intermediate circadian typology, while SUD patients slept less hours, displaying a morning typology. The DST showed the highest daily activation and stability for the SUD group, even when compared with the HC group. The presence of schizophrenia (SZ + and SZ) was related to a DST pattern with a reduced amplitude determined by a wakefulness impairment, which was more pronounced for SZ patients whose sleep period was adequate. The assessment of circadian rhythms in under treatment male patients with SZ should be focused on the diurnal period as a possible marker of either treatment adherence or patient's recovery, irrespective of the presence of a comorbid SUD. Further research with additional objective measures may provide knowledge transferable to therapeutic strategies and could be useful to establish possible endophenotypes in the future.