bluuebunny/crossref_metadata_2025_split huggingface dataset:
Individual and Joint Associations of Depression‐Related Symptoms and Sleep Quality With Overall Survival Among Patients With Ovarian Cancer: Evidence From a Prospective Cohort Study
Authors: Sun Jia-Nan , Li Yi-Zi , Wang Lan , Song Xin-Jian , Liu Jia-Xin , Liu Jia-Cheng , Wang Jia-Yi , Li Yu , Chen Yu-Han , Liu Jia-Ming , Xu Jin , Liu Ke-Xin , Bao Qi , Sun Ming-Li , Wu Lang , Gao Song , Li Xiao-Ying , Huang Dong-Hui , Ma Qi-Peng , Tao Tao , Wu Qi-Jun , Gong Ting-Ting 
Published: January 2025

Background: As the evidence linking depression and sleep quality to overall survival (OS) is lacking, we aim to evaluate the individual and joint associations of depression‐related symptoms and sleep quality with OS among patients with ovarian cancer (OC).Method: A total of 554 patients with OC were included. Depression‐related symptoms and sleep quality were measured using the Patient Health Questionnaire (PHQ‐9) and the Pittsburgh Sleep Quality Index (PSQI). The primary analysis utilized the average levels of depression‐related symptoms and sleep quality by averages of PSQI score and PHQ score between pre‐diagnosis and post‐diagnosis. Deaths were ascertained until February 16, 2023, via medical records and active follow‐up. Cox proportional hazard regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of the joint and individual associations of sleep quality and depression‐related symptoms with OC survival.Result: A total of 205 deaths occurred during a median follow‐up of 44.6 months. The average level of depression‐related symptoms and sleep quality were independently associated with OS (HRdepression vs. no depression = 1.55, 95% CI = 1.10–2.17; HRpoor sleep vs. good sleep = 2.05, 95% CI = 1.51–2.75). We documented multiplicative and additive interactions between these two factors in relation to OS (Pinteraction < 0.01; relative excess risk due to interaction = 0.16, 95% CI = 0.01–0.31). Combinations of depression‐related symptoms and poor sleep quality were positively associated with OC mortality (HR = 2.61, 95% CI = 1.70–4.00), compared to patients with good sleep quality and without depression‐related symptoms.Conclusion: Poor OC survival was observed among patients with poor sleep quality and depression‐related symptoms, independently and jointly.
The Truth and Reconciliation Commission as a Transcendent Function
Authors: Myers Steve 
Published: January 2025

Abstract
Barbara Cerminara (2024) has argued that the Truth and Reconciliation Commission (TRC) was not a transcendent function because it created a moral split between redeemed and resentful victims. She says this discredited and marginalised those who refused to reconcile, prioritised reconciliation over addressing inequalities, suppressed opposition, failed to acknowledge societal complexities, and did not integrate opposition for genuine transformation. Cerminara raises many good points and important issues, but these do not lead to the conclusion that the TRC was not a transcendent function. On the contrary, they illustrate advanced and nuanced aspects of the transcendent function and demonstrate why it is a multi-faceted and ongoing work. A holistic analysis shows that the TRC transcended and reconciled many conflicts, contributing to the overall work of dismantling apartheid. However, no transcendent function achieves complete wholeness and other apartheid-dismantling transcendent functions are required to continue the work.
Un essai en vue de résoudre une antinomie : aux origines du calcul benthamien. Bentham a-t-il résolu un problème posé par Pascal ? (Tome 146, n°1-2, (2025))
Authors: Cléro Jean-Pierre 
Published: January 2025

Résumé
Dans l’utilitarisme benthamien, le calcul, en fournissant une commensurabilité entre les langues, n’assure-t-il pas une universalité qu’aucune langue ne paraît pouvoir assurer par elle-même en raison de son inévitable contingence dont on s’aperçoit quand on la confronte avec les autres langues ? Une difficulté apparaît lorsqu’on prend en compte que Bentham a autant insisté sur l’aspect « calcul » de sa doctrine que sur ses aspects d’« utilité » et de « plaisir ». Si l’on veut bien reconnaître que les affects soient radicalement dépendants des langues, faut-il dire que les calculs dépendent aussi des langues et que « deux plus deux égale quatre » est une affaire de langage ? Pour obtenir une concordance entre langue vernaculaire, langue savante, plaisir et calcul, le relativisme de Bentham n’a-t-il pas été contraint d’aller jusque-là ? Toutefois, Bentham n’en reste pas à cette antinomie ; le but de la présente recherche est de montrer comment elle se résout.
Freedom of Association in Japan
Authors: Okada Junta 
Published: January 2025

Abstract
This article provides a brief overview of the history and current situation of freedom of association in the Constitution of Japan. Part i introduces the related provisions of freedom of association in the Constitution, including labour unions, religious corporations, universities and families. Part ii presents a brief history of the period before the current Constitution was established. Part iii examines the laws that limit associations based on the Constitution. Part iv considers the potential of freedom of association by analysing the original drafts of the Constitution of Japan. We further review the direction of theory of freedom of association by laying out the situation of academic discussions in Japan.
First episode of psychosis in rural Greece: A multi-center study of the Mobile Mental Health Units
Authors: Peritogiannis Vaios , Botsari Ioanna-Athina , Fragouli-Sakellaropoulou Athina , Filla Iliana , Garmpi Aikaterini , Dimopoulou Maria , Gavriilidis Stavros , Vgontzas Alexandros , Samakouri Maria ,   Coordinating Committee of the Mobile Mental Health Units, Tsoli Fotini , Kousta Iliana Lazogiorgou , Balomenou Maria , Zianni Afroditi , Fanti Roberta , Pistola Dimitra , Paschalidou Anna , Kondili Eleni , Arvaniti Aikaterini 
Published: January 2025

Background: Over the last decades the study of schizophrenia-spectrum disorders has been focused on early and comprehensive intervention during the first episode of psychosis (FEP), but studies in rural settings are only rare. In Greece mental healthcare in rural areas is mostly delivered by the locally-based Mobile Mental Health Units (MMHUs). Aims: The aim of the present study was to address treatment of FEP patients by the MMHUs in rural areas in Greece, focusing on patients with a first episode of schizophrenia. Method: This is a multicenter, retrospective observational study with the participation of nine MMHUs across several areas in rural mainland and some islands of Greece. Patients of the age range of 15 to 55 years with a diagnosis of non-affective psychosis were included in the study. Results: The study sample consisted of 216 patients, while analysis was performed for patients with a diagnosis of schizophrenia ( n = 153, 70.8% of the sample). Most patients were males ( n = 93, 60.8%), with a mean age at first presentation 34.9 years ( Md = 34.5, SD = 11.94). The mean duration of untreated psychosis (DUP) was 7.85 months ( Md = 3, IQR = 10.00) and was shorter in younger (15–25 years) patients. More than 60% of patients had been successfully engaged to treatment with the MMHUs, with a mean follow-up duration of 5.17 years ( Md = 5.00, IQR = 5.00). Younger patients (26–35 years) tend to disengage from treatment, while those aged 36 to 45 years were more likely to continue follow-up. A reduction of 47.22% in hospital admissions among patients with schizophrenia was observed over follow-up of patients by the MMHUS. Conclusion: The most noteworthy findings of the study are the low percentage of patients seeking help from the MMHUs, compared to the expected cases and the high attendance rate of those that are examined in this context. Further research on psychosis/schizophrenia in the rural context is warranted.
Mental health professionals’ perspectives and suggestions on religious and superstitious activities engagement of patients with serious mental illness: A national survey in Thailand
Authors: Wainipitapong Sorawit , Hataiyusuk Somboon , Khanthavudh Chonmanan , Phetsayanavin Vitchayut , Wiwattarangkul Teeravut , Aniwattanapong Daruj 
Published: January 2025

Background: Patients with serious mental illness (SMI) often engage in religious and superstitious activities. The implications of such engagements remain unclear, with no established guidelines for mental health professionals. Aims: This study aimed to survey perspectives and gather suggestions from various disciplines within mental healthcare regarding the engagement in religious/superstitious activities of SMI patients: schizophrenia spectrum disorders, bipolar disorder, major depressive disorder. Method: This cross-sectional study was conducted between November and December 2023 among Thai mental health professionals. Participants used 10-point Likert scales to rate their agreement levels for engaging each activity. Additional suggestions were obtained through textual responses, which were subsequently summarised and synthesised. Results: Of the 403 professionals participated, the majority were female (73.2%), Buddhist (87.6%) and psychiatrists (42.2%), with a median age of 34.0 years. Among patients with active symptoms, patients with major depressive disorder tended to receive the highest mean agreement scores for engagement, while patients with schizophrenia consistently scored the lowest across most activities. Similar trends were observed among patients in remission. From textual responses, two key themes were synthesised: (1) environmental factors and (2) impacts on natural courses. Conclusions: Patients with active schizophrenia received the lowest levels of agreement while patients with major depressive disorder tended to receive the highest mean agreement scores on engaging religious/superstitious activities.
Associations between violent and sexual childhood trauma and maladaptive coping in patients with functional seizures
Authors: Libbon Randi H , Watson Meagan , Ramocan Sunita , Pennetti Abbie , Strom Laura , Giano Zachary 
Published: January 2025

Objective Functional seizures (FS) are a highly debilitating symptom of functional neurological disorder (FND). FS requires a multi-disciplinary approach to treatment because the patient’s initial presentation is to neurology, emergency medicine, or primary care and treatment consists of psychotherapy. People with FS commonly experience severe childhood trauma, particularly sexual trauma. The authors aimed to investigate associations between reported trauma and maladaptive coping mechanisms in the FS population. Methods This retrospective, observational study reports on 137 patients enrolled in the FS Clinic at the University of Colorado between March 2020 - March 2021. Multiple linear regression was used to reveal associations between self-reported childhood sexual and violent trauma and maladaptive coping mechanisms of self-blame and disengagement on the Brief COPE. A quantile regression was generated for each of these outcomes. Results Results showed that violent and sexual trauma were experienced by 47.5% and 61.6% of the population sample, respectively. Of those exposed to violent trauma, 27.2% perceived it as extremely severe while 43.4% of those exposed to sexual trauma perceived it as extremely severe. Quantile regressions for self-blame and disengagement showed significance for the 25th percentile of those who experienced violent trauma. Self-blame was significantly associated with the 50th and 75th percentile of those exposed to sexual trauma. Conclusions This evidence supports the value of identifying trauma experienced by individuals with FS as it is associated with specific coping mechanisms that may affect treatment. Identifying prior trauma and resulting coping mechanisms can potentially assist in individualizing care for people with FS.
Effect of del Nido cardioplegia in patients with reduced left ventricular ejection fraction: A meta-analysis
Authors: Yamashita Yoshiyuki , Baudo Massimo , Magouliotis Dimitrios E. , Cabrucci Francesco , Sicouri Serge , Ramlawi Basel 
Published: January 2025

Purpose Research on the safety and efficacy of del Nido cardioplegia in adult patients with reduced left ventricular ejection fraction (LVEF) is limited. We evaluated the effect of del Nido cardioplegia on early outcomes of cardiac surgery in this cohort. Methods PubMed, Scopus, and the Cochrane Central Register of Controlled Trials were searched through August 2024 to conduct a meta-analysis comparing del Nido to other cardioplegia in adult patients with reduced LVEF (≤50%). Primary endpoint was early mortality, and secondary endpoints included morbidities, aortic cross-clamp time and postoperative LVEF before discharge. A random-effect model was used to estimate the pooled effect size. Results Seven studies met our eligibility criteria, including three propensity score-matched studies with a total of 1160 patients. Conventional blood cardioplegia was used exclusively as a control solution in the included studies. The incidence of early mortality was similar between the del Nido and control groups, with a pooled odds ratio of 0.94 [95% confidence interval: 0.52; 1.71] ( p = .822). Postoperative stroke ( p = .680), renal failure ( p = .832), atrial fibrillation ( p = .412), and aortic cross-clamp time ( p = .153) were also comparable between the two groups. Postoperative LVEF was significantly higher in the del Nido group compared to the control group, with a standardized mean difference of 0.52 [95% confidence interval: 0.07; 0.96] ( p = .034). Conclusions In adult patients with reduced LVEF undergoing cardiac surgery, del Nido cardioplegia provides comparable mortality and morbidity rates compared to conventional blood cardioplegic solutions, with the potential to offer protective effects on myocardial function.
Efficacy and safety of PD-1 inhibitor plus chemotherapy in advanced nasopharyngeal carcinoma: A meta-analysis
Authors: Yan Xin , Chen Suhua , Dai Guoping , Liu Yingxin 
Published: January 2025

Background: The combination of programmed cell death protein 1 (PD-1) inhibitors and chemotherapy has shown promising results in the treatment of various malignancies. This meta-analysis aims to evaluate the effectiveness and safety of combing PD-1 inhibitor with chemotherapy in patients with advanced NPC. Methods: A thorough search of the literature was carried out using comprehensive methods. The assessed outcomes included overall survival (OS), progression-free survival (PFS), objective response rate (ORR), disease control rate (DCR), and adverse events (AEs). Results: This meta-analysis included seven studies with a total of 1204 patients. The use of a combination therapy involving PD-1 inhibitor and chemotherapy demonstrated significant improvements in OS (HR=0.60, 95%CI: 0.45, 0.80; P<0.001), PFS (HR=0.51, 95%CI: 0.42, 0.61; P<0.001), ORR (RR=1.23, 95%CI: 1.07, 1.40; P=0.003) and DCR (RR=1.13, 95%CI: 1.03, 1.23; P=0.003) compared to other treatments in patients with advanced NPC. Subgroup analyses based on PD-1 inhibitor type, chemotherapy regimen and study design indicated that these factors influenced OS but not PFS. Prognostic factor analysis consistently demonstrated a PFS benefit associated with the combination treatment across various patient subgroups. The incidences of AEs, grade 3 or higher AEs were comparable between the two groups. However, the combination group was significantly more likely to discontinue treatment because of AEs. Conclusion: This meta-analysis provides evidence supporting the effectiveness and safety of PD-1 inhibitor plus chemotherapy in advanced NPC. The combination therapy showed superior outcomes in terms of OS, PFS, ORR, and DCR.
Knotless Versus Knotted Suture Anchors for Labral Repair of the Hip: A Systematic Review of Clinical and Biomechanical Outcomes
Authors: Johns William L. , Baumann Anthony N. , Callaghan Megan E. , Walley Kempland C. , Patel Neel K. , Salvo John 
Published: January 2025

Background: Arthroscopic labral repair of the hip is successfully performed with increasing frequency using either knotless or knotted suture anchors, each with its own risks and benefits. Purpose: To examine biomechanical and clinical outcomes for labral repair of the hip based on the use of knotted or knotless suture anchors. Study Design: Systematic review; Level of evidence, 4. Methods: A search was performed to retrieve clinical and biomechanical studies examining the use of knotless or knotted suture anchors for arthroscopic labral repair of the hip. The studied outcomes included functional outcome scores such as modified Harris Hip Score (mHHS) and Hip Outcome Score Activities of Daily Living, biomechanical outcomes, failure mechanisms, and complications such as revision/reoperation and conversion to total hip arthroplasty (THA). Results: A total of 47 articles met inclusion criteria for analysis (5 articles examining biomechanical outcomes and 42 reporting clinical outcomes). Included patients (N = 6185) who underwent hip labral repair had a mean age of 33.0 ± 8.5 years and follow-up time of 43.8 ± 18.4 months. The knotless group (n = 2719) had a mean preoperative mHHS of 63.3 ± 4.1 and postoperative mHHS of 86.3 ± 2.8 at a mean follow-up time of 47.2 ± 16.1 months. The knotted group (n = 2600) had a mean preoperative mHHS of 69.5 ± 8.3 and postoperative mHHS of 88.8 ± 5.5 with a mean follow-up time of 44.8 ± 18.1 months. The most common reason for failure of knotless anchors in biomechanical studies was suture breakage or pullout, and for knotted anchors it was anchor pullout. Of the articles reporting on revisions and/or conversion to THA after labral repair, the knotless group had 225 reoperations (8.1%) and 123 cases of conversion to THA (4.4%). The knotted group had 101 reoperations (6.2%) and 31 cases of conversion to THA (1.9%). Conclusion: Arthroscopic management of labral repairs of the hip using either knotless or knotted suture anchors appears to be both safe and effective in reducing pain and improving function. Biomechanical evaluation suggests differing failure mechanisms in knotted versus knotless anchors. The rates of revision and conversion to THA are low overall, irrespective of knotted or knotless anchors.
No Difference in External Rotation Loss After Isolated Bankart Repair, Remplissage, or Latarjet: A Systematic Review and Meta-analysis
Authors: Gonzalez-Morgado Diego , Ardebol Javier , Noble Matthew B. , Galasso Lisa A. , Menendez Mariano E. , Denard Patrick J. 
Published: January 2025

Background: Despite the effectiveness of remplissage in reducing instability recurrence, debate remains about the loss of external rotation (ER) after this procedure. Purpose: To compare the loss of ER after primary isolated arthroscopic Bankart repair alone (BR), Bankart with remplissage (REMP), and Latarjet (LAT) procedures. Study Design: Meta-analysis; Level of evidence, 3. Methods: A literature search of 4 databases was conducted to identify comparative studies reporting ER after BR, REMP, or LAT. ER loss with the arm at side was collected, along with postoperative Rowe score, return to previous sport level, instability recurrence, reintervention, and noninstability complications. Dichotomous variables were assessed using odds ratios with 95% CIs, and continuous variables were analyzed using mean differences (MDs) with 95% CIs. A random-effects meta-analysis was used for continuous outcomes and dichotomous outcomes. Results: In total, 27 studies were included, consisting of 2100 patients: 824 in BR, 378 in REMP, and 898 in LAT groups. The mean ER loss was 6.8°± 11° after BR, 9.3°± 12.6° after REMP, and 0.8°± 20.4° after LAT. Comparing REMP and BR, the MD was 5.9° ( P = .13); between REMP and LAT, the MD was 9.6° ( P = .17). For Rowe scores, the MD was 3.46 ( P = .49) between REMP and BR and 0.24 ( P = .9) between REMP and LAT. Odds ratios for return to previous sport level were 1.08 ( P = .84) for REMP versus BR and 1.62 ( P = .09) for REMP versus LAT. Regarding instability recurrence, the odds ratio was 6.67 ( P = .04) for REMP versus BR and 1.43 ( P = .48) for REMP versus LAT. The odds ratio for reoperation for BR was 7.69 ( P = .05) compared with REMP, and the odds ratio for complications for LAT was 6.25 ( P = .02) compared with REMP. Conclusion: Remplissage reduces instability recurrence compared with isolated Bankart repair without any statistically significant difference in postoperative ER deficit. Remplissage may reduce the risk of reoperation compared with Latarjet with no difference in postoperative ER deficit or recurrence.
Arthroscopy Is at Least as Effective as Arthrotomy for Treatment of Septic Arthritis in Adults: A Systematic Review of Large and Intermediate Joints
Authors: Nudelman Brandon M. , Piple Amit S. , Ferkel Richard D. 
Published: January 2025

Background: Surgical options for septic arthritis include open arthrotomy or an arthroscopic procedure. The optimal surgical technique remains a matter of debate as acceptable results have been reported for both. Purpose: To evaluate the efficacy of arthroscopy versus arthrotomy for the treatment of septic arthritis in large and intermediate-sized joints. Study Design: Systematic review; Level of evidence, 3. Methods: A literature search was performed of the PubMed and Cochrane online databases through September 2023 identifying articles comparing arthroscopy with arthrotomy for the treatment of septic arthritis. Eligible articles included retrospective or prospective comparative studies investigating reoperation, perioperative complications, or clinical outcomes after arthroscopic or open treatment for septic arthritis of the shoulder, elbow, wrist, hip, knee, or ankle in adults. Results: In total, 23 articles with 34,248 patients met the inclusion criteria comparing arthroscopy with arthrotomy. In 14 of the 20 (70%) studies that reported on reoperation rates, there was no significant difference in arthroscopic versus open surgical management for septic arthritis. Four (20%) studies reported lower reoperation rates when arthroscopy was utilized compared with open arthrotomy. One single-institution study found arthrotomy to be more effective for shoulder septic arthritis, and another favored open surgery only in the presence of erosions. In 11 of 23 (47.8%) studies, no difference in complications or clinical outcomes was found. However, 11 of 23 (47.8%) studies comprising the shoulder, wrist, hip, knee, and ankle reported a significant benefit to arthroscopy for improved outcomes. Conclusion: Arthroscopic surgery for the treatment of septic arthritis involving the shoulder, wrist, hip, knee, and ankle appears to be safe and effective. Reoperation rates, short-term complications, and functional outcomes tend to be similar or in favor of arthroscopy when compared with arthrotomy.