bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing multivariable PI controller with multi-response optimization for a pilot plant binary distillation column: a robust design approach
Authors: Bhat Vinayambika S. , Indiran Thirunavukkarasu , Selvanathan Shanmuga Priya , Bhat Shreeranga 
Published: July 2023

Purpose
The purpose of this paper is to propose and validate a robust industrial control system. The aim is to design a Multivariable Proportional Integral controller that accommodates multiple responses while considering the process's control and noise parameters. In addition, this paper intended to develop a multidisciplinary approach by combining computational science, control engineering and statistical methodologies to ensure a resilient process with the best use of available resources.

Design/methodology/approach
Taguchi's robust design methodology and multi-response optimisation approaches are adopted to meet the research aims. Two-Input-Two-Output transfer function model of the distillation column system is investigated. In designing the control system, the Steady State Gain Matrix and process factors such as time constant (t) and time delay (?) are also used. The unique methodology is implemented and validated using the pilot plant's distillation column. To determine the robustness of the proposed control system, a simulation study, statistical analysis and real-time experimentation are conducted. In addition, the outcomes are compared to different control algorithms.

Findings
Research indicates that integral control parameters (Ki) affect outputs substantially more than proportional control parameters (Kp). The results of this paper show that control and noise parameters must be considered to make the control system robust. In addition, Taguchi's approach, in conjunction with multi-response optimisation, ensures robust controller design with optimal use of resources. Eventually, this research shows that the best outcomes for all the performance indices are achieved when Kp11 = 1.6859, Kp12 = −2.061, Kp21 = 3.1846, Kp22 = −1.2176, Ki11 = 1.0628, Ki12 = −1.2989, Ki21 = 2.454 and Ki22 = −0.7676.

Originality/value
This paper provides a step-by-step strategy for designing and validating a multi-response control system that accommodates controllable and uncontrollable parameters (noise parameters). The methodology can be used in any industrial Multi-Input-Multi-Output system to ensure process robustness. In addition, this paper proposes a multidisciplinary approach to industrial controller design that academics and industry can refine and improve.
Audit partner gender and the COVID-19 pandemic: the impact on audit fees and key audit matters
Authors: Murphy Peter , McLaughlin Craig , Elamer Ahmed A. 
Published: July 2023

Purpose
The purpose of this study is to analyze the influence of the COVID-19 pandemic on audit fees and the reporting of key audit matters (KAMs). Additionally, this study also looks into potential differences in the behavior of male and female audit partners during this period, adding to the existing research on gender's effect on different elements of the audit process.

Design/methodology/approach
This study used a sample of all FTSE 350 firms from before the COVID-19 pandemic and during the pandemic. It analyzed the data using Ordinary Least Squares regression analysis to test its hypotheses.

Findings
This paper provides early evidence on the impact of the COVID-19 pandemic on audit fees and KAM disclosures in the UK. The results of this study show an increase in audit fees during the pandemic and greater detail in the reporting of KAMs, with no significant difference between male and female audit partners. These findings will be of interest to audit firms and regulators as they assess the performance of auditors during the pandemic and evaluate the expanded audit report's effectiveness in providing sufficient information to financial statement users.

Originality/value
This study provides first-of-its-kind empirical evidence on how auditors in the UK reacted to the COVID-19 pandemic. The findings of this study will be of interest to audit firms, regulators, such as the Financial Reporting Council, and other stakeholders as they evaluate the performance of auditors during the crisis period. The results will help regulators assess the effectiveness of the expanded audit report in providing sufficient information during a time of heightened risk and scrutiny.
Accelerating sustainability through better reporting
Authors: An Esther 
Published: July 2023

Purpose
This paper aims to review and discuss City Developments Limited (CDL)’s 15-year sustainability reporting journey with GRI Standards as core for its blended reporting framework.

Design/methodology/approach
The paper draws on the knowledge and experience of the company’s reporting team from the perspective of CDL’s Chief Sustainability Officer.

Findings
To future-proof businesses against climate crisis and achieve relevant sustainable development goals, companies need to be committed to goal setting, tracking and reporting Environment, Social and Governance (ESG) performance for sustained growth. A robust and rigorous approach to sustainability reporting that incorporates both value and impact allows organisations to identify material ESG issues and determine risks and opportunities that will help organisations to enhance strategy and practices for long-term resilience and business growth.

Practical implications
This paper can help businesses to understand that the rising climate change agenda has led to substantial emphasis being placed on climate-related standards and disclosures.

Social implications
Businesses cannot manage without measuring performance. Reporting is critical for businesses to effectively integrate sustainability into their business strategy and operations to accelerate action towards a low-carbon economy.

Originality/value
This paper addresses the development of sustainability reporting trends and the benefits and challenges of using GRI as a core reporting framework in an evolving ESG reporting landscape from the perspective of a real estate company.
IgG4‐related pachymeningitis—Long term follow up and outcome of six patients
Authors: Yardimci Gozde Kubra , Arslan Doruk , Babaoğlu Berrin , Bolek Ertuğrul Cagri , Kilic Levent , Saglam Arzu , Tuncer Aslı , Söylemezoğlu Figen , Gocmen Rahşan , Oguz Kader K. , Tan Ersin , Karadag Omer 
Published: July 2023

AbstractObjectiveOur understanding of IgG4‐RD and pachymeningitis has grown substantially, but the optimal approach for diagnosis, management, and long‐term outcomes is still an area of uncertainty.MethodsHUVAC is a database for IgG4‐RD patients, this database was retrospectively evaluated for pachymeningeal disease. Demographic, clinical, serological, imaging, histopathological data, and treatment details were re‐interpreted in patients with pachymeningitis.ResultsAmong 97 patients with IgG4‐RD, 6 (6.2%) had pachymeningitis. None of these patients had extracranial features, and also, in most of the patients, serum IgG4 levels were normal. Tentorium cerebelli and transverse sinus dura were the most commonly involved in the posterior fossa. During 18 months of median follow‐up on steroid+‐rituximab, none of them relapsed as pachymeningitis.ConclusionOur patients were mainly older males with sole neurological involvement. Non‐specific headache was the most common manifestation, and serum IgG4 levels were not useful for diagnosis. Typical radiology and tentorial thickening should suggest IgG4‐RD and prompt an early biopsy. Moreover, accompanying hypophysitis could also be a clue. With steroids+ rituximab treatment, no relapse related to meningeal involvement was seen in long‐term follow‐up.
TransMCL enables the assembly of full‐length coding genes for collecting complete hierarchical orthogroups
Authors: Shen Jingting , Zhou Shengyu , Chen Yamao , Qi Ji 
Published: July 2023

Abstract

Transcriptome sequencing technologies have revolutionized the field of phylogenomics by facilitating the identification of homologous genes for species without whole genome sequences. To infer complex evolution relationship among eukaryotes, it is essential to obtain complete sequences of protein‐coding genes to provide informative mutations. However, transcriptomes in eukaryotes often consist of a large number of duplicated genes and alternative isoforms, bringing great challenges for developing effective tools to obtain complete coding gene sequences.

Here, we present a net‐flow based assembler TransMCL, which aims to assemble fragmented transcripts into complete sequences while eliminating redundant isoforms during homologue clustering. By employing Markov clustering strategies and homologous gene guidance, TransMCL can accurately assemble genes for multiple organisms in an affordable time frame, making it well‐suited for phylogenomic studies based on transcriptomic data.

Our results demonstrate that TransMCL can assemble 89.95%–92.95% of the total expressed genes into near‐complete transcripts on benchmark plant/animal datasets. Furthermore, applying TransMCL to multiple transcriptomes in a single run enhances the completeness of genes, even in the absence of guidance homologues from closely related species.

These findings highlight the potential of TransMCL in phylogenomic studies, enabling the comprehensive characterization of gene families at the whole genome scale. By overcoming the challenges of complex gene contents in eukaryotes, TransMCL can significantly enhance our understanding of evolution of gene families across species.
Bulgaria: Political Developments and Data in 2022
Authors: SPIROVA MARIA 
Published: July 2023

AbstractThe data entry reviews the major political developments in Bulgaria in 2022, including the governmental crisis of May–June 2022, the early elections in October 2022, the failure to form a new Cabinet in the last months of 2022, and the continuing de facto rule of President Radev. It also discusses the main issues in Bulgarian politics, including the position of GERB (i.e., Citizens for European Development of Bulgaria) in the political process, the Bulgarian ambivalent position on the Russian‐Ukrainian war, and the impact of the war on energy prices and general economic development in the country.
Aberrations in the progesterone pathway and the Th1/Th2 cytokine dichotomy – An evaluation of RPL predisposition in the northeast Indian population
Authors: Kashyap Natasha , Begum Anjuma , Ray Das Chandana , Datta Ratul , Verma Mohit Kumar , Dongre Anita , Husain Syed Akhtar , Ahmad Khan Luqman , Deka Bose Purabi 
Published: July 2023

AbstractProblemRecurrent pregnancy loss (RPL) is the spontaneous loss of two or more consecutive pregnancies prior to 20 weeks of gestation, occurring in 1% of the reproductive‐age population. It is a major cause of infertility in India with a staggering 7.46% prevalence rate.Method of studyBlood and product of conception (POCs) from RPL cases (n = 65) were enrolled for this study, along with cases of medically terminated pregnancy (MTP, n = 80) and term delivery cases (n = 90) as control. ELISA for progesterone and progesterone induced blocking factor (PIBF) levels was carried out, followed by mRNA expression analysis of progesterone receptor isoform B (PR‐B) and its downstream immunomodulatory effectors, namely, PIBF, IL‐10 and IL‐12. Screening of PROGINS haplotype of PR gene and PIBF polymorphism were also conducted to correlate with their respective gene expression profiles.ResultsSerum progesterone level was found to be comparable in the RPL and MTP cases. Although the mRNA expression of PR‐B was found to be downregulated in the RPL cases, no significant PROGINS haplotype was observed. Presence of a single nucleotide polymorphism (SNP) in the PIBF gene (rs1372000) was more in healthy controls compared to RPL cases. Serum PIBF levels were found to be lower in the RPL cases with a resultant increase in IL‐12 and a decrease in IL‐10 mRNA expression in these cases.ConclusionsThis study indicates that progesterone, acting through PIBF, modulates the immunological state of pregnancy to be Th1‐biased in RPL, indicative of a pro‐inflammatory, labour‐like state not desired for a healthy pregnancy.
Prevalence estimates of eight big food allergies in Europe: Updated systematic review and meta‐analysis
Authors: Spolidoro Giulia C. I. , Ali Mohamed Mustafa , Amera Yohannes Tesfaye , Nyassi Sungkutu , Lisik Daniil , Ioannidou Athina , Rovner Graciela , Khaleva Ekaterina , Venter Carina , van Ree Ronald , Worm Margitta , Vlieg‐Boerstra Berber , Sheikh Aziz , Muraro Antonella , Roberts Graham , Nwaru Bright I. 
Published: July 2023

AbstractIn 2014, the European Academy of Allergy and Clinical Immunology published prevalence estimates for food allergy (FA) and food sensitization (FS) to the so‐called eight big food allergens (i.e. cow's milk, egg, wheat, soy, peanut, tree nuts, fish and shellfish) in Europe for studies published between 2000 and 2012. The current work provides 10‐year updated prevalence estimates for these food allergens. A protocol was registered on PROSPERO before starting the research (reference number CRD42021266657). Six databases were searched for studies published 2012–2021, added to studies published up to 2012, resulting in a total of 93 studies. Most studies were graded as at moderate risk of bias. The overall pooled estimates for all age groups of self‐reported lifetime prevalence were as follows: cow's milk (5.7%, 95% confidence interval 4.4–6.9), egg (2.4%, 1.8–3.0), wheat (1.6%, 0.9–2.3), soy (0.5%, 0.3–0.7), peanut (1.5%, 1.0–2.1), tree nuts (0.9%, 0.6–1.2), fish (1.4%, 0.8–2.0) and shellfish (0.4%, 0.3–0.6). The point prevalence of food challenge‐verified allergy were as follows: cow's milk (0.3%, 0.1–0.5), egg (0.8%, 0.5–1.2), wheat (0.1%, 0.01–0.2), soy (0.3%, 0.1–0.4), peanut (0.1%, 0.0–0.2), tree nuts (0.04%, 0.02–0.1), fish (0.02%, 0.0–0.1) and shellfish (0.1%, 0.0–0.2). With some exceptions, the prevalence of allergy to common foods did not substantially change during the last decade; variations by European regions were observed.
Low prevalence of antimicrobial resistant organisms (methicillin resistant Staphylococcus aureus, extended beta‐lactamase producing Enterobacteriaceae, and vancomycin resistant enterococci) in bulk tank milk in New South Wales, Australia
Authors: Rowe S , Cunningham C , Ingenhoff L , Norris JM , Zadoks RN 
Published: July 2023

ObjectiveEstimate the presence of methicillin resistant Staphylococcus aureus (MRSA), extended beta‐lactamase (ESBL) producing Enterobacteriaceae, and vancomycin resistant enterococci (VRE) in bulk tank milk in dairy herds in New South Wales (NSW), Australia.MethodsBulk tank milk samples (n = 80) were collected from dairy farms (n = 40, i.e. 2 per farm) in NSW during 2021. Bacteria were cultured using selective chromogenic indicator media with isolate identity confirmed using biochemical testing, Gram stain, and MALDI‐TOF mass spectroscopy. Antimicrobial resistance (AMR) was confirmed using antibiotic disk diffusion.ResultsNo samples tested positive to the targeted AMR organisms.ConclusionThe prevalence of MRSA, ESBL‐producing Enterobacteriaceae, and VRE is low in NSW dairy herds.
Antidepressant prescribing patterns and adverse events following introduction of a National Prescribing Indicator to monitor dosulepin usage in Wales
Authors: Chaplin Katherine , Bracchi Robert C. , Haines Kathryn E. , Routledge Philip Alexander , Deslandes Paul N. 
Published: July 2023

AimsLimiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011, the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in patients prescribed dosulepin following introduction of the NPI.MethodsAn e‐cohort study was conducted. Adult patients receiving regular dosulepin prescriptions between October 2010 and March 2011 were included. Characteristics of patients who were continued on dosulepin, were switched to an alternative antidepressant or whose dosulepin was discontinued following introduction of the NPI were compared.ResultsIn total, 4121 patients were included. Of these, 1947 (47%) continued dosulepin, 1487 (36%) were switched and 692 (17%) discontinued. Of the 692 who discontinued, 92% did not receive a prescription for another antidepressant during the follow‐up period. Patients whose dosulepin was discontinued were older and were less commonly coprescribed benzodiazepines. During follow‐up, recorded incidence of selected adverse events was low across all groups and no significant difference was observed.ConclusionOver half of patients had discontinued dosulepin at the end of the period when the NPI was in place. Further interventions may have been required to have a greater impact on prescribing. This study provides some reassurance that dosulepin discontinuation can be a successful strategy, and that the risk of the adverse events investigated was unlikely to have been greater in those who had dosulepin discontinued than in those in whom dosulepin had been continued.
Beneficial impact of tax reforms on tax revenue performances in Togo: Myth or reality?
Authors: Bayale Nimonka , Tchagnao Abdou‐Fataou , Nagou Madow , Tchila Pouwemdéou 
Published: July 2023

AbstractTax reforms are often motivated by their potential to improve tax revenue mobilization. However, their actual impacts are difficult to quantify. Using cross‐country panel data over the period 2000–2021, this article evaluates the impact of the 2012 tax reforms on tax revenue performance in Togo. We follow the Synthetic Control Method (SCM) estimation procedures. After comparing the observed evolution of Togo's tax revenue output in the period 2013–2021 with that of synthetic Togo, our estimates show that an accumulated yearly average gain is about 3.09% of GDP. Hence, the article concludes that after 9 years of reform, the improvement in Togo's tax performance is remarkable. However, more tax‐related and institutions‐related reforms are crucial to make Togo's tax system more buoyant and sustainably improve tax revenue mobilization.
The effect of the Affordable Care Act Medicaid expansion on consumer bankruptcies
Authors: Laberge Maude , Djiffa Kodjo‐Maawuegnigan 
Published: July 2023

AbstractMedical expenses have been associated with a large proportion of consumer bankruptcies in the United States. The objective of this study is to examine the relationship between the Medicaid expansion implemented in the context of the Affordable Care Act and consumer bankruptcy, overall and by chapter filing. We used a longitudinal study design with a study period of 2008–2017. We tested three approaches: difference‐in‐differences, fixed effect panel linear regression, and triple difference. We constructed a panel dataset from 2008 to 2017 with states’ data using data from various sources on insurance, bankruptcy filings, and characteristics that may affect bankruptcy, such as income and ethnicity. The outcomes were the annual rates of consumer bankruptcies overall and by chapter at the state level. Between 2008 and 2017, the overall unadjusted bankruptcy filing rate fell from 0.36% to 0.24%. We found that the expansion was associated with a decrease in overall consumer bankruptcy varying between 0.035 and 0.039 percentage points and that the intensity of the effect was modulated by the intensity of the treatment. Results were consistent across models and suggest that the Medicaid expansion had a significant negative effect on overall bankruptcy filings and specifically on Chapter 7 filings.
Closing the gap between existing large‐area imaging research and marine conservation needs
Authors: McCarthy Orion S. , Contractor Kanisha , Figueira Will F. , Gleason Arthur C. R. , Viehman T. Shay , Edwards Clinton B. , Sandin Stuart A. 
Published: July 2023

AbstractEmerging technology has immense potential to increase the scale and efficiency of marine conservation. One such technology is large‐area imaging (LAI), which relies on structure‐from‐motion photogrammetry to create composite products, including 3‐dimensional (3‐D) environmental models, that are larger in spatial extent than the individual images used to create them. Use of LAI has become widespread in certain fields of marine science, primarily to measure the 3D structure of benthic ecosystems and track change over time. However, the use of LAI in the field of marine conservation appears limited. We conducted a review of the coral reef literature on the use of LAI to identify research themes and regional trends in applications of this technology. We also surveyed 135 coral reef scientists and conservation practitioners to determine community familiarity with LAI, evaluate barriers practitioners face in using LAI, and identify applications of LAI believed to be most exciting or relevant to coral conservation. Adoption of LAI was limited primarily to researchers at institutions based in advanced economies and was applied infrequently to conservation, although conservation practitioners and survey respondents from emerging economies indicated they expect to use LAI in the future. Our results revealed disconnect between current LAI research topics and conservation priorities identified by practitioners, highlighting the need for more diverse, conservation‐relevant research using LAI. We provide recommendations for how early adopters of LAI (typically Global North scientists from well‐resourced institutions) can facilitate access to this conservation technology. These recommendations include developing training resources, creating partnerships for data storage and analysis, publishing standard operating procedures for LAI workflows, standardizing methods, developing tools for efficient data extraction from LAI products, and conducting conservation‐relevant research using LAI.
Identifying conservation priority areas for North American bumble bee species in Canada under current and future climate scenarios
Authors: Liczner Amanda R. , Schuster Richard , Richardson Leif L. , Colla Sheila R. 
Published: July 2023

AbstractMany bumble bee species are declining globally from multiple threats including climate change. Identifying conservation priority areas with a changing climate will be important for conserving bumble bee species. Using systematic conservation planning, we identified priority areas for 44 bumble bee species in Canada under current and projected climates (year 2050). Conservation priority areas were identified as those that contained targeted amounts of each species predicted occurrence through climate envelope models, while minimizing the area cost of conserving the identified conservation priority areas. Conservation priority areas in the two periods were compared to established protected areas and land cover types to determine the area of current and future priority sites that are protected and the types of landscapes within priority areas. Notably, conservation priority areas were rarely within established protected areas. Priority areas were most often in croplands and grasslands, mainly within the mountain west, central and Southern Ontario, Northern Quebec, and Atlantic Canada under all climate scenarios. Conservation priority areas are predicted to increase in elevation and latitude with climate change. Our findings identify the most important regions in Canada for conserving bumble bee species under current and future climates including consistently selected future sites.