bluuebunny/crossref_metadata_2025_split huggingface dataset:
Renal replacement therapy via popliteal vein for exhausted vascular access in emergency: A case report
Authors: Alptekın Gulen Sezer 
Published: March 2023

AbstractA 59 year‐old man was admitted as his left antecubital arterio‐venous fistula was thrombosed, and hemodialysis could not be succeeded for the last two sessions. It was a brachio‐basilic fistula without transposition, which also required thrombectomy 8 months ago, and had been created 18 months before. He had multiple catheter insertions during the period of 6 years. Following the failed catheter insertions from both jugular and femoral veins, an ultrasound‐guided venography via the left popliteal vein demonstrated the intact left popliteal and femoral vein with well‐developed collaterals at the level of occluded left iliac vein. A temporary hemodialysis catheter was placed through the popliteal vein with an antegrade manner under ultrasound guidance in prone position, which effectively worked during hemodialysis sessions afterwards. Transposition of basilic vein was performed. Following the wound recovery, arterialized basilic vein has started to be used effectively for hemodialysis, and the popliteal catheter was displaced.
Pathogenic NKT cells attenuate urogenital chlamydial clearance and enhance infertility
Authors: Armitage Charles W. , Carey Alison J. , Bryan Emily R. , Kollipara Avinash , Trim Logan K. , Beagley Kenneth W. 
Published: March 2023

AbstractUrogenital chlamydial infections continue to increase with over 127 million people affected annually, causing significant economic and public health pressures. While the role of traditional MHCI and II peptide presentation is well defined in chlamydial infections, the role of lipid antigens in immunity remains unclear. Natural killer (NK) T cells are important effector cells that recognize and respond to lipid antigens during infections. Chlamydial infection of antigen‐presenting cells facilitates presentation of lipid on the MHCI‐like protein, CD1d, which stimulates NKT cells to respond. During urogenital chlamydial infection, wild‐type (WT) female mice had significantly greater chlamydial burden than CD1d−/− (NKT‐deficient) mice, and had significantly greater incidence and severity of immunopathology in both primary and secondary infections. WT mice had similar vaginal lymphocytic infiltrate, but 59% more oviduct occlusion compared to CD1d−/− mice. Transcriptional array analysis of oviducts day 6 post‐infection revealed WT mice had elevated levels of Ifnγ (6‐fold), Tnfα (38‐fold), Il6 (2.5‐fold), Il1β (3‐fold) and Il17a (6‐fold) mRNA compared to CD1d−/− mice. In infected females, oviduct tissues had an elevated infiltration of CD4+‐invariant NKT (iNKT) cells, however, iNKT‐deficient Jα18−/− mice had no significant differences in hydrosalpinx severity or incidence compared to WT controls. Lipid mass spectrometry of surface‐cleaved CD1d in infected macrophages revealed an enhancement of presented lipids and cellular sequestration of sphingomyelin. Taken together, these data suggest an immunopathogenic role for non‐invariant NKT cells in urogenital chlamydial infections, facilitated by lipid presentation via CD1d via infected antigen‐presenting cells.
Transepidermal water loss and stratum corneum hydration in forearm versus hand palm
Authors: Mayrovitz Harvey N. 
Published: March 2023

AbstractBackgroundSkin measurements of transepidermal water loss (TEWL) and stratum corneum hydration (SCH) reflect different aspects of skin physiology. Since epidermal water loss depends on epidermal‐to‐air water vapor gradients, a possible quantitative relationship between TEWL and SCH may exist. This investigation's purpose was to test the possible TEWL‐SCH relationship.Materials and MethodsSCH and TEWL were measured noninvasively on forearm and palmer thenar eminence (hand) in 40 young adults (20 males) along with total body fat percentage (FAT) via bioimpedance.ResultsA significant positive nonlinear correlation (p < 0.001) was detected between SCH and TEWL in hands of the male cohort that occurred when SCH exceeded a threshold level. This threshold level was not exceeded in male or female forearms and forearms did not display a SCH‐TEWL correlation. There was a weak inverse dependence of TEWL on FAT on both forearm and hand (p < 0.05), but no SCH‐FAT relationship was observed. TEWL values on the forearm and hand were moderately correlated with each other (p = 0.002) but SCH values were not.ConclusionThe findings clarify the relationship between forearm and palmer hydration and TEWL values, and their relationship to total body fat percentages in young healthy adults. The significant correlation between palmer stratum corneum hydration and palmer TEWL that was discovered in the male but not the female cohort suggests a threshold hydration level for which TEWL depends both on skin barrier function and stratum corneum hydration. This implies that conditions with increased SCH may in part account for elevated TEWL values.
Estimating spatiotemporal aggregation scales by revisiting the spatiotemporal L‐function
Authors: Yan Xiaorui , Pei Tao , Song Ci , Liu Xiaohan 
Published: March 2023

AbstractAs an important statistical tool for spatial data, the L‐function is widely used in the estimation of the spatial aggregation scale. However, for heterogeneous spatiotemporal points, the formulation of the existing spatiotemporal L‐function makes it liable to produce poor estimates of spatiotemporal aggregation scales, which is essential in revealing process evolutions, such as spatiotemporal scopes of seismic sequence and spatiotemporal spread extents of an epidemic. This technical note analyzes the mechanism whereby the existing L‐function incorrectly estimates the spatiotemporal aggregation scales, and presents a modified spatiotemporal L‐function that overcomes these issues. Moreover, a local version of the improved L‐function is developed to identify aggregations for validation. The results of simulation experiments and a seismic case study demonstrate that our method estimates the spatiotemporal aggregation scales accurately, which verify the veracity of our corrections to the existing spatiotemporal L‐function.
Morphobiometry of the scleral ossicle rings in Chelonia mydas sea turtles
Authors: Boyda‐Andrade Stelamares , Silva Danielle Nascimento , Raposo Ana Cláudia , Estrela‐Lima Alessandra , Oriá Arianne. P 
Published: March 2023

AbstractObjectiveScleral ossicle rings of reptiles have endoskeletal functions that are not completely understood. Moreover, descriptive reports on the anatomy of those rings are scarce. We tried to make an anatomical description that could contribute to a better understanding of their functions.Animal Studied and ProceduresWe quantified, histologically characterized and evaluated the morphobiometry of the scleral ossicles, and measured the aditus orbitae of 25 sea turtle (Chelonia mydas) heads.ResultsThe aditus orbitae represented about one‐third of the total head length and the mean area of the internal opening of each ring was up to 8.37% of the aditus orbitae area. The mean internal diameter of the rings (6.32 mm) was characteristic of scotopic species and the most frequent number of ossicles per ring varied between 11 and 12. Two new classifications were proposed for the ossicle types: plus‐Verzahnung (+V) and minus‐Verzahnung (‐V). The bone tissue revealed a lamellar arrangement typical of compact and resistant bones.ConclusionThe obtained data may be used to support and expand the understanding of functions, animal activity patterns, distinctions between taxa and taphonomic interpretations.
Unlicensed assistive personnel’s care for persons with or at risk of delirium: a scoping review protocol
Authors: Mailhot Tanya , Maheu-Cadotte Marc-André , Bourbonnais Anne , Yevchak Sillner Andrea , Charchalis Mélanie , Rodriguez Dora , Lavoie Patrick 
Published: March 2023

Objective:
The objective of this review is to describe the nature and extent of the literature regarding unlicensed assistive personnel’s involvement in delivering care to persons with or at risk of delirium.

Introduction:
Initiatives that promote the involvement of unlicensed assistive personnel in providing additional supervision and care to persons with or at risk of delirium have been developed. Since no standardized approach guides unlicensed assistive personnel’s involvement with persons with or at risk of delirium, and since inconsistent training and expectations may pose a threat to the safety and quality of care, it is essential to clarify their role with persons with or at risk of delirium.

Inclusion criteria:
This review will consider articles published in peer-reviewed journals, dissertations, theses, book chapters, and conference papers in French or English. Quantitative, qualitative, or mixed method studies that report on the development, implementation, or evaluation of the role of unlicensed assistive personnel in contexts of delirium will be included. We will consider editorials and opinion papers only if they report on the development, implementation, or evaluation of the role of unlicensed assistive personnel.

Methods:
Records will be identified via CINAHL, ProQuest Dissertations & Theses Global, Embase, MEDLINE, APA PsycINFO, and Web of Science. Two independent reviewers will select studies and extract data using a piloted form. Data will be synthesized narratively, using descriptive statistics and a tabular format. A consultation phase will include approximately 24 unlicensed assistive personnel and registered nurses who will be invited to comment on the review findings.
Impact of educational and psychological interventions compared with standard care in college/university students with autism spectrum disorder: a systematic review protocol
Authors: Kantor Jiří , Li Jiaoli , Du Jian , Svobodová Zuzana , Klugar Miloslav , Salehi-Pourmehr Hanieh , Hampton David , Smolíková Monika , Kantorová Lucia , Marečková Jana , Zmeškalová Daniela , Munn Zachary 
Published: March 2023

Objective:
This review will explore the impact of educational and psychological interventions on educational, social, behavioral, and mental health outcomes in students with autism spectrum disorder in tertiary education.

Introduction:
This systematic review will inform a new guideline on support for students with autism spectrum disorder in the tertiary education environment. These students face multiple educational, behavioral, social, and health-related problems that require effective interventions.

Inclusion Criteria:
Participants are students with autism spectrum disorder in a tertiary education study program. Educational and psychological interventions will be included, such as accommodations, meta-cognitive and self-regulation training, psychological counseling, social skills training, and peer-mentoring/academic coaching. The comparator will be standard care. The study outcomes will include academic drop-out rates and evaluations, learning skills, social skills and social engagement, behavior, mental health (including anxiety, stress, and depression), and employment after graduation. This review will consider quantitative studies only.

Methods:
A 3-step search strategy will be used to find both published and unpublished studies in MEDLINE, CINAHL, APA PsycINFO, SocINDEX, Web of Science, Clinical Trials, ProQuest Dissertations and Theses, Open Dissertations, ERIC, WHO ICRTP, and Google Scholar. There will be no date or language limitations. All stages of article screening, critical appraisal, and data extraction will be conducted by 2 independent reviewers with the resolution of any disagreements done via consensus or through a senior reviewer. If possible, the included studies will be pooled using meta-analysis. The degree of certainty of the evidence will be assessed according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.

Systematic review registration number:
PROSPERO CRD42022323554
Define the Lyapunov Exponents forψ-Fractional Differential System
Authors: N'Gbo N'Gbo , Tang Jianhua 
Published: March 2023

AbstractIn this article, we focus on the relations between the asymptotics of solutions and the sensitivity to initial values of fractional differential systems. To investigate this problem, we consider the ψ-fractional calculus, which is considered to be a generalization of those of Riemann–Liouville and Hadamard. For this purpose, we define Lyapunov exponents for ψ-fractional differential systems and estimate their upper bounds. Examples are presented to demonstrate the accuracy of our results.
Semi-Implicit Integration and Data-Driven Model Order Reduction in Structural Dynamics With Hysteresis
Authors: Goswami Bidhayak , Chatterjee Anindya 
Published: March 2023

AbstractStructural damping is often empirically rate-independent wherein the dissipative part of the stress depends on the history of deformation but not its rate of change. Hysteresis models are popular for rate-independent dissipation; and a popular hysteresis model is the Bouc-Wen model. If such hysteretic dissipation is incorporated in a refined finite element model, then the model involves the usual structural dynamics equations along with nonlinear nonsmooth ordinary differential equations for a large number of internal hysteretic states at Gauss points used within the virtual work calculation. For such systems, numerical integration is difficult due to both the distributed nonanalytic nonlinearity of hysteresis as well as large natural frequencies in the finite element model. Here, we offer two contributions. First, we present a simple semi-implicit integration approach where the structural part is handled implicitly based on the work of Piché, while the hysteretic part is handled explicitly. A cantilever beam example is solved in detail using high mesh refinement. Convergence is good for lower damping and a smoother hysteresis loop. For a less smooth hysteresis loop and/or higher damping, convergence is noted to be roughly linear on average. Encouragingly, the time-step needed for stability is much larger than the time period of the highest natural frequency of the structural model. Subsequently, data from several simulations conducted using the above semi-implicit method are used to construct reduced order models of the system, where the structural dynamics is projected onto a few modes and the number of hysteretic states is reduced significantly as well. Convergence studies of error against the number of retained hysteretic states show very good results.
A solution-based approach to reducing adult sanitary & PPE waste from rest homes in Aotearoa
Authors: Arnott Gabby 
Published: March 2023

Aim: This research project aims to explore solutions for minimising landfill contributions from incontinence and personal protective equipment (PPE) waste produced by rest home facilities (both care/support units and retirement villages) in Aotearoa.Research Question: What evidence-based solutions to decrease sanitary and PPE waste exist and can these be applied to rest homes in Aotearoa?
Method: A narrative literature review was conducted surrounding PPE and sanitary waste minimisation, alongside interviews with industry representatives and waste experts, to ascertain the practicalities of such solutions in Aotearoa. A waste hierarchy for sanitary waste was created; highly recommended solutions were place at the top and least recommended at the bottom based on factors such as accessibility, environmental impact, and patient wellbeing.
Results: The order of these solutions was (from top to bottom): pelvic floor muscle exercises, reusing, recycling, organic ecomposition, landfilling, and incineration. Fewer opportunities were available for waste minimisation of PPE; current alternatives to landfilling include companies such as Future Post (an organisation recycling face masks into functional fence posts). Developing technologies such as the disinfecting and recycling of PPE through Auckland University are emerging, although theyare not currently accessible for public contributions.
Conclusion: For both sanitary and PPE waste, the requirement of such products should be minimised where possible (such as through awareness of hand hygiene (PPE) and pelvic floor muscle strength (sanitary waste)). If necessary, reusable rather than single-use products should be applied.
Supervised by Ray O'Brien, Head of Sustainability, Sustainability Office, University of Otago and Arveen Horsefield, Arvida.Scholarship funded by: Arvida, Metlife Care, BUPA, Summerset, and Oceania Healthcare
Green Hydrogen in New Zealand Online News
Authors: Greaves Caelum 
Published: March 2023

Due to its position as an emerging technology, one which remains largely in the innovation stage, green hydrogen’s scope in the Public view is largely unknown. With New Zealand investing heavily in the development of green hydrogen, the importance of public perception is only going to grow over the coming years. Using articles from New Zealand’s various online news sources, this talk uses a sociolinguistic framework to investigate the way green hydrogen is represented in New Zealand online media. By analyzing online articles through a combination of media analysis and critical discourse analysis, we can begin to understand the way green hydrogen is being framed within the discursive environment of New Zealand.
New technologies do not enter the public eye as isolated instances of innovation and are instead tied into a complex network of larger discourses, political, economic, historical, scientific, and emotional. Critical discourse analysis allows us to consider how these various contexts relate to both the creation and consumption of media surrounding green hydrogen. Using various linguistic frameworks, such as positioning theory, and capital D discourse theory, articles can be deconstructed and related to the various larger narratives which surround green hydrogen, such as sustainability, economic stability, and energy independence.
Supervised by: Abbi Virens, Centre for Sustainability, Univerisity of Otago
On stable type IIA de-Sitter vacua with geometric flux
Authors: Shukla Pramod 
Published: March 2023

AbstractWe present a class of tachyon-free (stable) AdS as well as dS solutions in the context of type IIA orientifold compactifications. This model is based on a type IIA setting having geometric flux which, in addition, also includes the usual NS–NS three-form flux $$\textrm{H}_3$$

H
3

and the RR p-form fluxes $$\textrm{F}_p$$

F
p

for $$p \in \{0, 2, 4, 6\}$$

p
∈
{
0
,
2
,
4
,
6
}

. Although all the saxionic moduli are stabilized, there remains a combination of the RR axions which is flat, and the dS solution is realized through the D-term effects induced by the geometric fluxes, without which one can only have AdS solutions. Using flux scaling arguments we also discuss how to engineer a parametric control in these models, in the sense of realizing the respective AdS/dS solutions in large volume, weak string-coupling as well as large complex-structure regime. We also discuss open possibilities (e.g. about the unknown status on having the complete set of Bianchi identities) under which such tachyon-free dS solutions may or may not be viable.
Toward learning Lattice Boltzmann collision operators
Authors: Corbetta Alessandro , Gabbana Alessandro , Gyrya Vitaliy , Livescu Daniel , Prins Joost , Toschi Federico 
Published: March 2023

Abstract
In this work, we explore the possibility of learning from data collision operators for the Lattice Boltzmann Method using a deep learning approach. We compare a hierarchy of designs of the neural network (NN) collision operator and evaluate the performance of the resulting LBM method in reproducing time dynamics of several canonical flows. In the current study, as a first attempt to address the learning problem, the data were generated by a single relaxation time BGK operator. We demonstrate that vanilla NN architecture has very limited accuracy. On the other hand, by embedding physical properties, such as conservation laws and symmetries, it is possible to dramatically increase the accuracy by several orders of magnitude and correctly reproduce the short and long time dynamics of standard fluid flows.

Graphic abstract
The neutron facility at NCSR ‘Demokritos’ and neutron activation research activities of NTUA
Authors: Vlastou R. 
Published: March 2023

AbstractAt the 5.5 MV Tandem T11/25 Accelerator Laboratory of NCSR “Demokritos” quasi-monoenergetic neutron beams can be produced in the energy ranges ∼15–21 MeV by means of the 3H(d,n)4He reaction, ∼4–11 MeV via the 2H(d,n)3He reaction, ∼2.0–5.3 MeV using the 3H(p,n)3He reaction and ∼120–650 keV via the 7Li(p,n)7Be reaction. The maximum flux has been determined to be of the order of $10^{5}\text{--}10^{6}\text{ n/cm}^{2}\text{s}$

10

5

–

10

6

n/cm
2

s
, implementing reference reactions, while the flux variation of the neutron beam is monitored using a BF3 detector and a BC501A scintillator. The neutron beams have been characterized using the multiple foil activation technique as well as extensive simulations and have been used for cross section measurements of neutron induced reactions implementing again the activation technique.
Microenvironment-Driven Dynamic Chromatin Changes in Glioblastoma Recapitulate Early Neural Development at Single-Cell Resolution
Authors: Pine Allison R. , Cirigliano Stefano M. , Singhania Richa , Nicholson James , da Silva Bárbara , Leslie Christina S. , Fine Howard A. 
Published: March 2023

Abstract

The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular states, hindering elucidation of the underlying transcriptional regulation of these states. Using our glioblastoma cerebral organoid model, we profiled the chromatin accessibility of 28,040 single cells in five patient-derived glioma stem cell lines. Integration of paired epigenomes and transcriptomes within the context of tumor-normal host cell interactions was used to probe the gene-regulatory networks underlying individual GBM cellular states in a way not readily possible in other in vitro models. These analyses identified the epigenetic underpinnings of GBM cellular states and characterized dynamic chromatin changes reminiscent of early neural development that underlie GBM cell state transitions. Despite large differences between tumors, a shared cellular compartment made up of neural progenitor-like cells and outer radial glia–like cells was observed. Together, these results shed light on the transcriptional regulation program in GBM and offer novel therapeutic targets across a broad range of genetically heterogenous GBMs.

Significance:
Single-cell analyses elucidate the chromatin landscape and transcriptional regulation of glioblastoma cellular states and identify a radial glia–like population, providing potential targets to disrupt cell states and improve therapeutic efficacy.
Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment
Authors: Sekhar Konjeti R. , Freeman Michael L. 
Published: March 2023

Abstract
Nucleophosmin (NPM1) is frequently mutated in acute myeloid leukemia, and NPM1 expression is elevated in several cancer types. NPM1 is a multifunctional oligomeric protein involved in numerous cellular functions that include participating in liquid–liquid phase separation, ribosome biogenesis, chaperoning of histones, and modulation of transcription. In this review, we discuss the underappreciated role of NPM1 in DNA damage repair, specifically Polη-mediated translesion synthesis, base excision, and homologous recombination and highlight the therapeutic potential of NPM1 targeting in cancer treatment.