bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consensus recommendations for the assessment and treatment of perinatal obsessive–compulsive disorder (OCD): A Delphi study
Authors: Mulcahy Melissa , Long Christian , Morrow Teagan , Galbally Megan , Rees Clare , Anderson Rebecca 
Published: May 2023

AbstractThe perinatal period is one of increased vulnerability to parents experiencing the onset of, or an increase of existing, obsessive–compulsive disorder (OCD) symptoms. Existing OCD and perinatal mental health best practice guidelines do not detail specific considerations relevant to OCD in the perinatal period (‘Perinatal OCD’). Perinatal OCD risks being undiagnosed or misdiagnosed, and subsequently untreated or mistreated, with potential negative impacts for individuals and families experiencing this problem, highlighting the importance of specific guidance. This study employed a modified Delphi survey methodology to establish recommended best practice for the assessment and treatment of perinatal OCD. A literature review identified 103 initial best practice recommendations, and participants suggested 18 further recommendations. These recommendations were rated for importance over three survey rounds by two expert panels, comprising of 15 professionals with clinical or research expertise in perinatal OCD and 14 consumers with lived experience of perinatal OCD. One-hundred and two statements were endorsed for inclusion in the final set of recommendations for clinical best practice with perinatal OCD. These recommendations inform practice across eight themes; psychoeducation, screening, assessment, differential diagnosis, case care considerations, treatment, partners & families, and culture & diversity. This novel study is the first to collate and outline a set of clinical best practice recommendations, developed using the consensus perspectives of both individuals with lived experience and professionals with relevant expertise, for supporting individuals with perinatal OCD and their families. Differences between panel perspectives, and directions for future research are also discussed.
Deterioration of the Littoral–Benthic Ecosystem Following Recent Expansion of Signal Crayfish (Pacifastacus leniusculus) in the World’s Clearest Large Lake
Authors: Scordo Facundo , Girdner Scott F. , San Pedro Aldo , Seitz Carina , Chandra Sudeep 
Published: May 2023

AbstractSome biological invasions can result in algae blooms in the nearshore of clear lakes. We studied if an invasive crayfish (Pacifastacus leniusculus) modified the biomass and community composition of benthic macroinvertebrates and therefore led to a trophic cascade resulting in increased periphyton biomass, elevated littoral primary productivity, and benthic algae bloom in a lake with remarkable transparency [Crater Lake, Oregon, USA]. After quantifying the changes in the spatial distribution of invasive crayfish over a 13-year period, we compared biomass and community composition of littoral–benthic macroinvertebrates, periphyton biovolume, community composition, nutrient limitation, and the development of benthic algae bloom in locations with high and low crayfish density. In addition, we determined if the alteration in community structure resulted in directional changes to gross primary production and ecosystem respiration. The extent of crayfish distribution along the shoreline of Crater Lake doubled over a 13-year period, leaving less than 20% of the shoreline free from crayfish. At high crayfish density sites, benthic macroinvertebrate biomass was 99% lower, and taxa richness was 50% lower than at low crayfish areas. High crayfish sites show tenfold greater periphyton biovolume, sixfold higher periphyton biomass (chlorophyll a), twofold higher metabolic productivity, and the presence of large filamentous algae (Cladophora sp.). The invasion of crayfish had negative consequences for a lake protected under the management of the USA National Park Service, with direct impacts on many levels of ecological organization.
In vitro activities of omadacycline, eravacycline, cefiderocol, apramycin, and comparator antibiotics against Acinetobacter baumannii causing bloodstream infections in Greece, 2020–2021: a multicenter study
Authors: Galani Irene , Papoutsaki Vassiliki , Karaiskos Ilias , Moustakas Nikolaos , Galani Lamprini , Maraki Sofia , Mavromanolaki Viktoria Eirini , Legga Olga , Fountoulis Kimon , Platsouka Evangelia D. , Giannopoulou Panagiota , Papadogeorgaki Helen , Damala Maria , Chinou Efrosini , Pasxali Aggeliki , Deliolanis Ioannis , Vagiakou Helen , Petinaki Efthymia , Chli Anastasia , Vagdatli Eleni , Kazila Polyzo , Papaioannou Vassiliki , Kontopoulou Konstantina , Ferke Atalia Noemi , Moraitou Eleni , Antoniadou Anastasia , Giamarellou Helen 
Published: May 2023

AbstractResistance of Acinetobacter baumannii to multiple clinically important antimicrobials has increased to very high rates in Greece, rendering most of them obsolete. The aim of this study was to determine the molecular epidemiology and susceptibilities of A. baumannii isolates collected from different hospitals across Greece. Single-patient A. baumannii strains isolated from blood cultures (n = 271), from 19 hospitals, in a 6-month period (November 2020–April 2021) were subjected to minimum inhibitory concentration determination and molecular testing for carbapenemase, 16S rRNA methyltransferase and mcr gene detection and epidemiological evaluation. 98.9% of all isolates produced carbapenemase OXA-23. The vast majority (91.8%) of OXA-23 producers harbored the armA and were assigned mainly (94.3%) to sequence group G1, corresponding to IC II. Apramycin (EBL-1003) was the most active agent inhibiting 100% of the isolates at ≤16 mg/L, followed by cefiderocol which was active against at least 86% of them. Minocycline, colistin and ampicillin-sulbactam exhibited only sparse activity (S <19%), while eravacycline was 8- and 2-fold more active than minocycline and tigecycline respectively, by comparison of their MIC50/90 values. OXA-23-ArmA producing A. baumannii of international clone II appears to be the prevailing epidemiological type of this organism in Greece. Cefiderocol could provide a useful alternative for difficult to treat Gram-negative infections, while apramycin (EBL-1003), the structurally unique aminoglycoside currently in clinical development, may represent a highly promising agent against multi-drug resistant A. baumanni infections, due to its high susceptibility rates and low toxicity.
Simulation training approaches in intracranial aneurysm surgery—a systematic review
Authors: Joseph Fredrick J. , Vanluchene Hanne E. R. , Bervini David 
Published: May 2023

Abstract
Background
With the increasing complexity and decreasing exposure to intracranial aneurysm surgery, training and maintenance of the surgical skills have become challenging. This review elaborated on simulation training for intracranial aneurysm clipping.

Methods
A systematic review was performed according to the PRISMA guidelines to identify studies on aneurysm clipping training using models and simulators. The primary outcome was the identification of the predominant modes of the simulation process, models, and training methods associated with a microsurgical learning curve. The secondary outcomes included assessments of the validation of such simulators and the learning capability from the use of such simulators.

Results
Of the 2068 articles screened, 26 studies met the inclusion criteria. The chosen reports used a wide range of simulation approaches including ex vivo methods (n = 6); virtual reality (VR) platforms (n = 11); and static (n = 6) and dynamic (n = 3) 3D-printed aneurysm models (n = 6). The ex vivo training methods have limited availability, VR simulators lack haptics and tactility, while 3D static models lack important microanatomical components and the simulation of blood flow. 3D dynamic models including pulsatile flow are reusable and cost-effective but miss microanatomical components.

Conclusions
The existing training methods are heterogenous and do not realistically simulate the complete microsurgical workflow. The current simulations lack certain anatomical features and crucial surgical steps. Future research should focus on developing and validating a reusable, cost-effective training platform. No systematic validation method exists for the different training models, so there is a need to build homogenous assessment tools and validate the role of simulation in education and patient safety.
Association between cooling temperature and outcomes of patients with heat stroke
Authors: Chen Lan , Xu Shuying , Yang Xiaoling , Zhao Junlu , Zhang Yuping , Feng Xiuqin 
Published: May 2023

AbstractThis study explored the relationship between body temperature and adverse outcomes in patients with heat stroke to identify the optimal target body temperature within the first 24 h. This retrospective, multicentre study enrolled 143 patients admitted to the emergency department and diagnosed with heat stroke. The primary outcome was the in-hospital mortality rate, while secondary outcomes included the presence and number of damaged organs and neurological sequelae at discharge. A body temperature curve was built using a generalized additive mixed model, and the association between body temperatures and outcomes was established by logistic regression. The threshold and saturation effects were used to explore the targeted body temperature management. Cases were divided into the surviving and non-surviving groups. The cooling rate within the first 2 h was significantly higher in the survival group than the non-survival group (β: 0.47; 95% confidence interval [CI]: 0.09–0.84; P = 0.014), while the non-survival group exhibited a lower body temperature within 24 h (β: − 0.06; 95% CI: − 0.08 to − 0.03; P ≤ 0.001). Body temperature after 2 h (odds ratio [OR]: 2.27; 95% CI: 1.14–4.50; P = 0.019) and lowest temperature within 24 h (OR: 0.18; 95% CI: 0.06–0.55; P = 0.003) were significantly related to in-hospital mortality rate. When the body temperature at 0.5 h was 38.5–40.0 °C, the number of damaged organs was at its lowest. In patients with heat stroke, both hyperthermia and hypothermia were associated with adverse outcomes. Hence, an accurate body temperature management is required during the early stages of care.
Non-toxic, high selectivity process for the extraction of precious metals from waste printed circuit boards
Authors: Merli Giulia , Becci Alessandro , Amato Alessia , Beolchini Francesca 
Published: May 2023

AbstractThe work presented here focused on the extraction of gold (Au), silver (Ag) and palladium (Pd) from electronic waste using a solution of ammonium thiosulfate. Thiosulfate was used as a valid alternative to cyanide for precious metal extractions, due to its non-toxicity and high selectivity. The interactions between sodium thiosulfate, total ammonia/ammonium, precious metal concentrations and the particle size of the waste printed circuit boards (WPCBs) were studied by the response surface methodology (RSM) and the principal component analysis (PCA) to maximize precious metal mobilization. Au extraction reached a high efficiency with a granulometry of less than 0.25 mm, but the consumption of reagents was high. On the other hand, Ag extraction depended neither on thiosulfate/ammonia concentration nor granulometry of WPCBs and it showed efficiency of 90% also with the biggest particle size (0.50 < Ø < 1.00 mm). Pd extraction, similarly to Au, showed the best efficiency with the smallest and the medium WPCB sizes, but required less reagents compared to Au. The results showed that precious metal leaching is a complex process (mainly for Au, which requires more severe conditions in order to achieve high extraction efficiencies) correlated with reagent concentrations, precious metal concentrations and WPCB particle sizes. These results have great potentiality, suggesting the possibility of a more selective recovery of precious metals based on the different granulometry of the WPCBs. Furthermore, the high extraction efficiencies obtained for all the metals bode well in the perspective of large-scale applications.
SEOM-GEMCAD-TTD clinical guidelines for the systemic treatment of metastatic colorectal cancer (2022)
Authors: Fernández Montes Ana , Alonso Vicente , Aranda Enrique , Élez Elena , García Alfonso Pilar , Grávalos Cristina , Maurel Joan , Vera Ruth , Vidal Rosario , Aparicio Jorge 
Published: May 2023

Abstract
Colorectal cancer (CRC) is the second leading cause of cancer deaths in Spain. Metastatic disease is present in 15–30% of patients at diagnosis and up to 20–50% of those with initially localized disease eventually develop metastases. Recent scientific knowledge acknowledges that this is a clinically and biologically heterogeneous disease. As treatment options increase, prognosis for individuals with metastatic disease has steadily improved over recent decades. Disease management should be discussed among experienced, multidisciplinary teams to select the most appropriate systemic treatment (chemotherapy and targeted agents) and to integrate surgical or ablative procedures, when indicated. Clinical presentation, tumor sidedness, molecular profile, disease extension, comorbidities, and patient preferences are key factors when designing a customized treatment plan. These guidelines seek to provide succinct recommendations for managing metastatic CRC.
Entropy and alternative entropy functionals of fractional Gaussian noise as the functions of Hurst index
Authors: Malyarenko Anatoliy , Mishura Yuliya , Ralchenko Kostiantyn , Shklyar Sergiy 
Published: May 2023

AbstractThis paper is devoted to the study of the properties of entropy as a function of the Hurst index, which corresponds to the fractional Gaussian noise. Since the entropy of the Gaussian vector depends on the determinant of the covariance matrix, and the behavior of this determinant as a function of the Hurst index is rather difficult to study analytically at high dimensions, we also consider simple alternative entropy functionals, whose behavior, on the one hand, mimics the behavior of entropy and, on the other hand, is not difficult to study. Asymptotic behavior of the normalized entropy (so called entropy rate) is also studied for the entropy and for the alternative functionals.
In situ stress determination in isotropic and anisotropic rocks and its application to a naturally fractured reservoir
Authors: Zhang Jincai , Fan Xin , Huang Zhiwen , Liu Zhongqun , Fan Zhihui , Liu Lin 
Published: May 2023

AbstractAnisotropies exist in many sedimentary rocks, particularly in naturally fractured reservoirs, causing horizontal stress anisotropies. Case studies indicate that when a rock formation contains high dip-angle fractures or contains horizontal factures (e.g. bedding planes), it has very distinguished horizontal stresses. In these cases, the conventional isotropic method for estimating horizontal stresses may give erroneous results. Using the theory of anisotropy, horizontal stresses in the vertical transverse isotropy (VTI) and horizontal transverse isotropy (HTI) models are derived for determining in situ stresses in naturally fractured rocks. Comparing with the isotropic model, the VTI model predicts a higher minimum or maximum horizontal stress, which is suitable for shales. In contrast, the HTI model gives a lower minimum stress than the isotropic model. A combined model based on the VTI and HTI models is proposed for estimating the minimum horizontal stress in a naturally fractured formation containing natural fractures with different dip angles. Measured data in the Xujiahe gas reservoir in China reveal that the minimum horizontal stresses and formation breakdown pressures decrease as the fracture dip angles increase, which is consistent to the derived HTI model. Natural fractures can result in a decrease of the minimum horizontal stress by up to 3 MPa/km and a reduction of the formation breakdown pressure by up to 10 MPa/km in the studied area. Combining the proposed anisotropic model to the measured data of natural fractures and horizontal stresses, the assessment of in situ stresses and their impact on hydraulic fracturing are proposed. Case study demonstrates that the proposed model gives a good prediction of the minimum horizontal stresses in the naturally fractured reservoir.
Researching (multiple) coordination of action in adult education organizations—Theoretical approaches, empirical findings and future perspectives
Authors: Schemmann Michael , Bonn Eva 
Published: May 2023

AbstractThe paper aims at analyzing how coordination of action is conceptualized and researched in the context of adult education. Selected perspectives from organization theory are explored with regard to their conceptualizations of coordination of action. Based on a narrative synopsis of studies from adult education research, the paper then shows that there are various actor constellations, coordination mechanisms and influencing factors marking coordination of action as a multi-faceted, multi-level and multi-perspective research phenomenon. Following, key parameters of a research program focusing on multiple coordination of action in adult education organizations are presented.
The Years of Lead. Memory, history, journalism, victims
Authors: Foot John 
Published: May 2023

‘Soprattutto un attore di quella drammatica fase della vita italiana è stato tuttavia privilegiato in modo schiacciante come oggetto di studio: il “soggetto terrorista”, ovvero i terroristi e le organizzazioni terroristiche.’(‘One kind of actor in that dramatic period of Italian life has been privileged above all others, in an overwhelming way by researchers and others: the terrorists themselves and their organisations.’ (Brizzi 2021, 11).
The Economic Reform of Female Monasticism in the Papal States of Clement VIII: Ideas, Actions, and Impacts
Authors: Harvey Isabel 
Published: May 2023

AbstractIn the Papal States of the end of the sixteenth century, most female monasteries were mendicant. In doing so, nuns violated many rules of the XXVth session of the Council of Trent: they obviously did not respect enclosure, but also were unable to survive only thanks to their real estate properties, as stated by the chapters 2, 3, and 16 of the De Regularibus et Monialibus decree. This financial situation of convents was addressed for the first time by Clement VIII (1592–1605), who led a broad economic reform all over his territory. How was the economic reform of convents led by Clement VIII applied in the local realities of the Papal States, what were its impacts on nuns, and how did they react to these changes? Based on the letters received by the Congregation of Bishops and Regulars in Rome during the Pontificate of Clement VIII, this article addresses the materiality and the local peculiarities of the economic reform of female convents in the dioceses of the Papal States, highlighting the strategies used by nuns to fight against change, negotiate accommodation, or adapt their daily lives to the new Roman requirements. Much less known and studied than the Tridentine enclosure, the economic reform desired by the same Council of Trent is an equally important change whose impacts durably transformed the daily life and identity of nuns.
Hidden in Plain Sight: John Cotton's Middle Way and the Making of the Cambridge Platform of Church Discipline
Authors: Winship Michael P. 
Published: May 2023

AbstractThe 1648 Cambridge Platform, Congregationalists’ first, guided New England Congregationalist church practice well into the next century. Yet the synodical deliberations that shaped the platform remain largely a closed book. Were the contents of all three preparatory platform drafts known, a baseline could be established for inferring those deliberations. But it has long been taken as a given that John Cotton's draft is missing.The now-recovered draft was, among other things, Cotton's vehicle for working reforms restraining Congregationalism's democratic and fissiparous tendencies into the Cambridge Platform. He had first laid out those reforms in Keyes of the Kingdom of Heaven (1644), a book that attracted widespread attention, including at the English Westminster and Savoy Assemblies. Yet the slender amount of scholarship on the Cambridge Platform has offered, at most, generalized acknowledgment, if any, of Cotton's considerable and complicated impact on it. That neglect leaves a large gap in our understanding of the platform, the synod, and Cotton himself, as well as of the unstable dynamics of clerical authority in an awkwardly peripheral emergent puritan church movement that emphasized lay empowerment.
Expanding north: first record of the beaded sea cucumber Euapta lappa at Madeira Island
Authors: Schäfer Susanne 
Published: May 2023

Abstract
This study provides the first record of the beaded sea cucumber Euapta lappa at Madeira Island. A single individual was observed during a nocturnal scuba dive at 17 m depth, presumably feeding. After having its previous northern limit in the North-east Atlantic at the Selvagens Islands, this record expands the known distribution and northern limit of this tropical species by about 300 km. This new record of yet another tropical species expanding its range northwards can be seen as another indication of the ongoing tropicalization in the marine environment of Macaronesia in the North-east Atlantic.
Role of social aversion in the motivations for tax law compliance
Authors: Malka Tiv Karnit 
Published: May 2023

AbstractDiscovering individuals' internal motivations for paying taxes is essential to a tax system since the basic assumption of any tax system is that most of the population pays their taxes voluntarily. This article examines the existence of a social aversion towards tax offenders in Israel as well as the variables that affect tax law compliance and increase tax payments. In this respect, the article presents quantitative questionnaire data collected by the author, which is based on a sample of 189 participants from Israel. The study shows that the social response to tax evaders exerts a greater impact on increasing tax law compliance than the fear of punishment per se and clarifies the importance of education for paying taxes.
Magnetically tuned SIW patch antenna based on nematic liquid crystal for 5G applications and satellite communication systems
Authors: Kouki Adel , Sboui Fakher , Latrach Lassaad 
Published: May 2023

AbstractThis paper presents a new design of a reconfigurable miscrostrip patch antenna based on a substrate-integrated waveguide (SIW). The antenna is resonant at the millimeter-wave (mmWave) 5G spectrum. The tuning technique consists of using a nematic liquid crystal (K15). An adjustable frequency band from 30.191 to 32 GHz is obtained, giving a tunable range of Δfr = 1.809 GHz. The maximum gain and efficiency reach the values of 7.61 and 9.07 dBi and 93 and 94%, respectively. The proposed SIW antenna loaded with liquid crystal was fabricated and tested. The experimental results correlated well with the simulation; however, the measured reflection coefficient plot shows a shift of the tuning range of 284 MHz, which is an acceptable outcome compared to simulation. A new approach of adopting the magnetic field as a technique to tune the resonance frequency has been used. The structure is characterized by its design simplicity, compactness, and fabrication process. The proposed antenna proves that the liquid crystal improves the performance of the antenna in the Ka band for 5G applications and satellite communication systems.