bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Komparatif Intensitas dan Hasil Belajar Siswa Laki-Laki Dan Siswa Perempuan di Madrasah Se Kota Tanjungpinang
Authors: Nur Muhammad , Hairunisa Hairunisa , Mariyah Siti 
Published: May 2023

Abstract: The purpose of the research is to find out how the intensity and learning outcomes differ between men and women in Madrasas in the city of Tanjungpinang. In this study, the research subjects were students of class XI and XII MAN Tanjungpinang and MAS Miftahul Ulum. Data analysis techniques used descriptive analysis and t test, with prerequisite tests, namely normality and homogeneity tests. The results of the Anava test on the designation of the significance value on the learning intensity were 0.121 (Sig. > 0.05; Ho was accepted). This means that there is no significant difference in the learning intensity of male and female students in madrasas throughout the city of Tanjungpinang. the average learning outcomes of women obtain learning outcomes that are more optimal than the learning outcomes of students from the male group. The results of the Anava test showed that the significance value of the learning outcomes was 0.121 (Sig. > 0.05; Ho was accepted). This means that there is no significant difference in the learning outcomes of male and female students in madrasas throughout the city of Tanjungpinang.
Abstrak: Adapun tujuan penelitain adalah untuk mengetahui bagaimanakah perbedaan intensitas dan hasil belajar antara siswa laki-laki dan perempuan di Madrasah se kota Tanjungpinang. Pada penelitian ini yang dijadikan subjek penelitian adalah siswa kelas XI dan XII MAN Tanjungpinang dan MAS Miftahul Ulum. Teknik analisis data menggunakan analisis deskriptif dan uji t, dengan uji prasyarat yaitu uji normalitas dan homogenitas. Hasil uji Anava pada menunjukan nilai signifikasi pada intensitas belajar tersebut adalah 0.121 (Sig. > 0.05; Ho diterima). Artinya Tidak ada perbedaan signifikan intensitas belajar siswa laki-laki dan perempuan di madrasah se-kota Tanjungpinang Hasil belajar rata-rata siswa laki-laki adalah 71.59 dan siswa perempuan adalah 74.26 tergambar dari pencapaian hasil belajar siswa secara personal maka tampak bahwa rata-rata hasil belajar perempuan memperoleh hasil belajar yang lebih maksimal dibandingkan dengan nilai hasil belajar siswa dari kelompok laki-laki. Hasil uji Anava pada menunjukan nilai signifikasi pada hasil belajar tersebut adalah 0.121 (Sig. > 0.05; Ho diterima). Artinya Tidak ada perbedaan signifikan hasil belajar siswa laki-laki dan perempuan di madrasah se-kota Tanjungpinang.
Manajemen Strategi Kerjasama dalam Pendidikan
Authors: Cahyono Imam , Syaifudin Muhammad , Andriani Tuti 
Published: May 2023

Abstract: This study aims to determine the management of cooperative strategies implemented in education. The results of the study show that the determination of a management strategy includes developing a vision, mission, and goals for improving the quality of education in schools together with the community to plan and develop long-term or short-term programs (annual including the budget). The benefits of cooperation indicate that there is an agreement between two or more people who are mutually beneficial and give contributions or roles that are by the strengths and potential of each party, so that the gains or losses achieved are proportional, meaning that they are by the parts and strengths of each party.
Abstrak: Penelitian ini bertujuan untuk mengetahui manajemen strategi kerjasama yang diimplementasikan dalam pendidikan. Hasil penelitian menunjukkan bahwa penetapan strategi manajemen meliputi pengembangan visi, misi dan tujuan peningkatan mutu pendidikan di sekolah bersama-sama dengan masyarakat untuk merencanakan dan menyusun program jangka panjang atau jangka pendek (tahunan termasuk anggarannya). Manfaat kerjasama menunjukkan adanya kesepakatan antara dua orang atau lebih yang saling menguntungkan dan memberi kontribusi atau peran yang sesuai dengan kekuatan dan potensi masing-masing pihak, sehingga keuntungan atau kerugian yang dicapai bersifat proporsional, artinya sesuai dengan peran dan kekuatan masing-masing pihak.
Antiviral Activity of Propyl Gallate against Replication of Dengue Virus Serotype 2: In Vitro and In Silico Study
Authors: Soetedjo Ariel Valentino , Desti Hidayati , Dewi Beti 
Published: May 2023

Introduction: Dengue fever (DF) and dengue hemorrhagic fever (DHF) are infectious diseases caused by dengue virus (DENV) with high mortality rates. The mainstay of treatment for DENV infection is supportive, since there were no commercial specific antiviral drug for DENV. Propyl gallate has potential to be an antivirus for DENV. However, the mechanism is still unknown. This study aims to identify the activity of propyl gallate in DENV-2 replication in vitro and analyze the binding energy of propyl gallate towards NS3 and NS5 protein in silico.
Methods: We used DENV serotype 2 New Guinea C and Vero cells for in vitro study. Focus and MTT assay was conducted to measure inhibition percentage and to measure viability percentage. Furthermore, in silico was conducted to identify the binding energy and inhibition constant of propyl gallate towards NS3 dan NS5 protein.
Results: The percentage inhibition of pre and post infection was 4,34±7,53% and 30,7±4,88% with viability of 94,64±0,4% and 95,31±3,38%, respectively. The binding energy of propyl gallate with NS5, NS3 protease, and NS3 helicase were -3,49 kcal/mol, -2,47 kcal/mol, and -3,72 kcal/mol.
Conclusion: Propyl gallate has high inhibition activity towards DENV-2 adhesion-replication in vitro with low binding energy to NS5 and NS3 in silico.
Checklist of the rupicolous vascular plant species on inselbergs in the Monumento Natural dos Pontões Capixabas, Espírito Santo, Brazil
Authors: Arantes Fabiula , De Paula Luiza , Forzza Rafaela 
Published: May 2023

Inselbergs are granitic and/or gneissic rocky outcrops and, in Brazil, the dome-shaped ones are called sugarloaves (pães de açúcar). They have an extremely specialized vegetation with high levels of endemism. Despite this, they are poorly studied and highly degraded. In northeastern Espírito Santo State, in southeastern Brazil, the Monumento Natural dos Pontões Capixabas (MONAPC) is a federal protected area created to guard some inselbergs threatened by mining, which is one of the main activities in the state. In this work, we provide the first checklist of the rupicolous vascular plant species in this protected area, which is based on field expeditions and searching for occurrence records in virtual herbaria.
We recorded 105 species in 36 families and 74 genera that inhabit the vegetation islands on the inselbergs within the official limits of MONAPC. A new species of Pleroma (Melastomataceae) was discovered and, it is being described.
Pour une alternative des relations interpersonnelles au travail, développer des Techniques Relationnelles
Authors: Combes Victor , Silva François 
Published: May 2023

Cet article aborde la façon dont sont envisagées les relations interpersonnelles au travail dans le cadre d’un changement de paradigme qui remet en question les valeurs et principes de la modernité. La notion de déliance est ainsi mobilisée pour traduire le délitement relationnel induit par l’exacerbation d’un individualisme. A contrario , le projet postmoderne représente une conception alternative de coopération dans les relations avec Autrui en correspondance à un projet de reliance. Pour concrétiser ce projet, il s’agit d’identifier les démarches qui permettent d’expérimenter et d’apprendre des manières de tisser des relations interpersonnelles alternatives par rapport à la vision verticale et réifiante induite par la modernité. Cet article suggère la possibilité de regrouper ces démarches autour de l’expression « techniques relationnelles » en revisitant des travaux sociologiques autour des notions de techniques du corps et de techniques sociales. Une de ces techniques est ainsi mise en lumière : le codéveloppement professionnel. À cet effet, nous nous appuyons sur une recherche effectuée dans une mutuelle qui a mis en place une démarche de codéveloppement. Ainsi, ces techniques relationnelles permettent de faire évoluer les relations interpersonnelles vers un cadre de confiance.
Militer de l’intérieur : les stratégies des réseaux professionnels LGBT
Authors: Buchter Lisa 
Published: May 2023

En dépit de l’essor des politiques diversité en France depuis les années 2000, peu d’entreprises et d’administrations se sont saisies des questions de lutte contre l’homophobie et la transphobie. Fondé sur une analyse textuelle et longitudinale d’archives complétée par des entretiens, l’article examine les stratégies de cinq réseaux internes portés par des « salarié·e·s militant·e·s », engagé·e·s de manière visible pour la cause lgbt sur leur lieu de travail. Ces réseaux internes de grandes entreprises ou d’administrations développent eux-mêmes des ressources et des services de prévention et de sensibilisation, et utilisent comme levier la réputation des employeurs à propos de leur engagement pour la diversité. Ces acteurs peuvent, à mesure qu’ils acquièrent une visibilité et une légitimité dans leur organisation, étendre le champ de leurs revendications et le périmètre de leurs actions, dénonçant de plus en plus vigoureusement l’inaction de leur employeur face aux discriminations à l’encontre des minorités sexuelles et de genre. Même s’ils proposent des actions modérées ou réformistes, ces réseaux participent à transformer de l’intérieur les politiques de ressources humaines.
Conceptual Approach to an AI-Based Adaptive Study Support System for Individualized Higher Education
Authors: Otto Frank , Kling Nico , Schumann Christian-Andreas , Tittmann Claudia 
Published: May 2023

In the context of the digital transformation, the targeted implementation of AI-based or AI-supported technologies in "teaching & learning" as well as "administration & service" holds considerable potential for organizational change and quality enhancement for higher education institutions. The use of AI in higher education teaching and services lags behind the level in research. Therefore, holistic solutions must be planned and implemented in unity of teaching and research for the AI-based support of the stakeholders’ inclusive administration, the further development or the establishment of new digital study programs and offers as well as the prospective qualification of university staff in the field of AI. The solutions must be analyzed, systematized, and structured to generate a conceptual approach via an integrated architecture with adaptive services.
This paper is an evolution of the concept presented at the Learning Ideas Conference 2022 and includes, in addition to explanations of the current state of the arts, the presentation of a systems-oriented approach for AI in higher education as well as the conception of the student lifecycle management at the author’s university. The paper ends with the presentation of a concept regarding a decision support system for individualized studying.
A lírica escura de Luís Quintais
Authors: Alves Ida 
Published: May 2023

Il s'agit d'analyser la poétique de Luís Quintais, l'une des voix les plus marquantes de la poésie portugaise contemporaine, dans sa dimension catastrophique, en considérant les façons dont le sujet contemporain occidental figure le monde où il habite, dans la mesure où tout tend à la ruine et à la disparition. Dans la poésie portugaise, une autre voix a déjà travaillé cette ruine sociale : Carlos de Oliveira. A l’époque actuelle, les poètes contemporains portugais, chacun à leur façon, disent cet espace ruiné de la vie, mais Luís Quintais indique plus anthropologiquement l'existence au bord du précipice. Nous parlons donc d'une « lyrique sombre », image omniprésente dans sa poésie.
Evidence Review for Preventing Osteoarthritis After an Anterior Cruciate Ligament Injury: An Osteoarthritis Action Alliance Consensus Statement
Authors:   Osteoarthritis Action Alliance, Secondary Prevention Task Group, Driban Jeffrey B. , Vincent Heather K. , Trojian Thomas H. , Ambrose Kirsten R. , Baez Shelby , Beresic Nicholas , Berkoff David J. , Callahan Leigh F. , Cohen Bruce , Franek Madison , Golightly Yvonne M. , Harkey Matthew , Kuenze Christopher M. , Minnig Mary Catherine , Mobasheri Ali , Naylor Adam , Newman Connie B. , Padua Darin A. , Pietrosimone Brian , Pinto Daniel , Root Hayley , Salzler Matthew , Schmitt Laura , Snyder-Mackler Lynn , Taylor Jeffrey B. , Thoma Louise M. , Vincent Kevin R. , Wellsandt Elizabeth , Williams Monette 
Published: May 2023

Context
The Osteoarthritis Action Alliance formed a secondary prevention task group to develop a consensus on secondary prevention recommendations to reduce the risk of osteoarthritis after a knee injury.

Objective
Our goal was to provide clinicians with secondary prevention recommendations that are intended to reduce the risk of osteoarthritis after a person has sustained an anterior cruciate ligament injury. Specifically, this manuscript describes our methods, literature reviews, and dissenting opinions to elaborate on the rationale for our recommendations and to identify critical gaps.

Design
Consensus process.

Setting
Virtual video conference calls and online voting.

Patients or Other Participants
The Secondary Prevention Task Group consisted of 29 members from various clinical backgrounds.

Main Outcome Measure(s)
The group initially convened online in August 2020 to discuss the target population, goals, and key topics. After a second call, the task group divided into 9 subgroups to draft the recommendations and supportive text for crucial content areas. Twenty-one members completed 2 rounds of voting and revising the recommendations and supportive text between February and April 2021. A virtual meeting was held to review the wording of the recommendations and obtain final votes. We defined consensus as &gt;80% of voting members supporting a proposed recommendation.

Results
The group achieved consensus on 15 of 16 recommendations. The recommendations address patient education, exercise and rehabilitation, psychological skills training, graded-exposure therapy, cognitive-behavioral counseling (lacked consensus), outcomes to monitor, secondary injury prevention, system-level social support, leveraging technology, and coordinated care models.

Conclusions
This consensus statement reflects information synthesized from an interdisciplinary group of experts based on the best available evidence from the literature or personal experience. We hope this document raises awareness among clinicians and researchers to take steps to mitigate the risk of osteoarthritis after an anterior cruciate ligament injury.
Mechanotransduction in Fibrosis
Authors: Chetambath Ravindran , Ravindran Nithya 
Published: May 2023

ABSTRACT
Mechanotransduction is the phenomenon of conversion of mechanical forces to biochemical signals in fibrosis. Knowledge on how mechanotransduction influences the behavior of cells and tissues will help to identify novel therapeutic targets for mechanomodulatory approaches. Innovative therapies based on these advances will potentially transform fibrotic healing into tissue regeneration.
Is the Term Brittle Asthma Obsolete? What is its Clinical Relevance in Routine Practice?
Authors: Chetambath Ravindran , John Jis B. 
Published: May 2023

ABSTRACT
Brittle asthma is a life-threatening phenotype of asthma and was considered relevant in clinical practice before the year 2000. After the introduction of GINA guidelines, this entity was not discussed much in literature and the phenotype was included in acute severe asthma. Even the GINA guideline-2022 update is silent about this phenotype. This article discusses brittle asthma phenotypes and examines the relevance of this entity in clinical practice.
Once a Remedy, Later a Disease
Authors: Shikha K. C. , Koshy Sudin , Arjun Padmanabhan 
Published: May 2023

ABSTRACT
Radiation-induced lung injury (RILI) encompasses any lung toxicity induced by radiation therapy (RT). It manifests acutely as radiation pneumonitis (RP) and chronically as radiation pulmonary fibrosis. It is usually seen in patients who have undergone thoracic irradiation for the treatment of lung, breast, or hematologic malignancies. The volume of lung irradiated and the mean lung dose are important risk factors. The diagnosis is usually based on a combination of typical symptoms (e.g., cough, dyspnea, and occasionally fever), timing, dose, and location of radiation therapy, compatible imaging findings, and exclusion of other causes. We report a case of a patient with breast cancer, who had received locoregional radiotherapy (RT) and then palliative RT for metastasis in the rib, following which she developed symptoms and radiological manifestations consistent with RILI. The patient recovered clinically and radiologically with conservative management. It was important to accurately diagnose the entity early since RP with moderate-to-severe symptoms and impaired respiratory function needs to be treated early to prevent irreversible lung damage.
Hydropneumothorax – Rare Presentation of Pulmonary Embolism with Methylenetetrahydrofolate Reductase Mutation with Hyperhomocysteinemia
Authors: Kunjumon Saby Anna , Neenu N. , Utpat Ketaki Vasudeo , Desai Unnati , Raj K. Aravind , Sable Sharad Bharat 
Published: May 2023

ABSTRACT
Pulmonary embolism (PE) is a relatively common cardiovascular event with high early mortality rates. Many risk factors play a role in the causation of PE including acquired as well as inherited. Methylenetetrahydrofolate reductase (MTHFR) gene mutation is one of the inherited etiologies for PE which cause hyperhomocysteinemia which can lead to PE. This in turn can result in secondary complications such as pneumothorax or hydropneumothorax, which are rare presentations of PE. Hereby, we present this unique case of a 17-year-old boy who presented with a hydropneumothorax which on further evaluation was found to be a complication of bilateral PE which was due to hyperhomocysteinemia with MTHFR A1298C mutation. Hence, we present this unique case with rare presentation as well as rare etiology for PE. This shows the significance for considering PE as one of the differentials in situations such as cavitations, pneumo or hydropneumothoraces, and hyperhomocysteinemias.
Management of Buerger's Disease (Thromboangiitis Obliterans) of the Lower Limb by Horizontal Distraction and Corticotomy by Ilizarov's Technique
Authors: Rohit Kumar , Verma Vikas 
Published: May 2023

Introduction:
Thromboangiitis obliterans (TAO), also known as Buerger's disease, is a disease of unknown etiology affecting small- and medium-sized blood vessels, mainly seen in heavy smokers. The characteristic features of this disease are distal ischemia, with patients having claudication, rest pain, and toe ulcers. The proper management of TAO is still a challenging problem. Various medical and surgical treatments have been tried with a variable success. Since it is a disease characterized by chronic ischemia, achieving neoangiogenesis could have a beneficial effect. Ilizarov has shown that corticotomy and distraction of bony fragments can increase the blood supply to the entire limb. TAO can be managed using this principle of distraction osteogenesis to induce neoangiogenesis. We conducted this study to evaluate the clinical outcomes of longitudinal tibial corticotomy and horizontal distraction with Ilizarov's fixator in Buerger's disease of the lower limb.

Materials and Methods:
Ten patients with clinically and radiologically proven Buerger's disease admitted to our hospital between 2019 and 2021 who had failed the conservative pharmacological modalities of treatment were included. A lateral tibial corticotomy and distraction was performed by the use of olive wires and two-ring frame with horizontal distraction mechanism. Lateral distraction was started after 10 days at the rate of 0.25 mm 6 h for 25 days to achieve a distraction of 2.5 cm. The frame was removed after consolidation of regenerate.

Results:
Of the 10 cases, eight patients became pain free, while one had a partial relief of pain and one patient worsened on treatment and underwent below-knee amputation. Three patients had at least one episode of pin site infection which improved with oral antibiotics and dressings. One patient had delayed consolidation of regenerate. The claudication distance improved at each follow-up for all but one patient.

Conclusion:
Neoangiogenesis by corticotomy and distraction offers a relatively simple and cost-effective surgical option to salvage ischemic limbs from amputations and provide pain relief, ischemic ulcer healing, and improved claudication distance, thus improving the quality of life.
Transosseous Suture-Aided Proximal Humeral Internal Locking Osteosynthesis Plate in Proximal Humerus Fractures
Authors: Bhargavan Vishnu , Shyam Roy A. S. , Shibu R. 
Published: May 2023

Background:
Fracture of the proximal humerus is the commonest fracture affecting the shoulder girdle in adults. Neer's 2, 3, and 4 part fractures are managed by operative fixation. Proximal humeral internal locking osteosynthesis (PHILOS) plate fixation is the treatment nowadays. However, accurate reduction of greater and lesser tuberosities may not be possible with a plate alone, which may lead to avascular necrosis of the humeral head. Transosseous suture fixation can accurately reduce the greater and lesser tuberosity fragments to shaft and head, but cannot maintain the reduction. A combination of transosseous suture fixation with PHILOS plate may be a viable option.

Objective of Study:
Our study was to evaluate functional outcome of transosseous sutures along with PHILOS plating for patients with proximal humerus fractures.

Materials and Methods:
The study was done as a prospective observational study of 40 consecutive patients with proximal humerus fractures, managed with transosseous suturing aided PHILOS plating. They were followed up for 6 months and evaluated using Constant Murley Scoring system.

Results:
The mean age of our patients was 52.86 years. The mechanism of injury was due to road traffic accident in 42.5% (17) and domestic falls in 57.5% (23). There were 20% two-part, 52.5% three-part, and 27.5% four-part fractures. Overall functional outcome was found to be good to excellent in 77.5% of our patients. The mean Constant Murley score achieved was 80.35. We found that patients with Neer's two-part and three-part fractures had the highest Constant scores (88.1 and 79.7. respectively) while patients with four-part had the lowest Constant scores (76). Patients <60 years showed better results.

Conclusion:
Transosseous suturing-aided PHILOS plating can be an excellent treatment option for osteosynthesis of complex proximal humerus fractures allowing early mobilization and good functional outcome. Transosseous suturing along with PHILOS plate can counteract the varus forces which can reduce complications such as late fracture displacement and avascular necrosis. There is no need for additional hardware, fibular graft, or exposure for the combined procedure to achieve a good outcome. Thorough knowledge of anatomy, proper fracture reduction and proper placement of locking plate are equally important for a superior outcome in these difficult fractures.