bluuebunny/crossref_metadata_2025_split huggingface dataset:
Working through multiple crises: the experience of psychotherapists and psychoanalysts in Lebanon
Authors: Nassif Rose Marie , Husseini Mayssa' El , Beaini Nour , Choueiri Tonnie , Tarazi-Sahab Layla , Moro Marie-Rose 
Published: July 2023

Abstract

Background
This research explores the impact of the COVID-19 pandemic on psychotherapists' practices and their ability to maintain a framework despite a shared reality with their patients. The specific focus in this article is on the Lebanese context, which is characterized by a series of crises including economic collapse, the COVID-19 pandemic, and the Beirut blast. The objective of this study was to examine how the destabilization of the meta-frame due to crises necessitates adaptations in theoretical knowledge, practice, and setting.
Methods
We conducted a qualitative study among a population consisting of mental health professionals, which were recruited in multiple countries through associations and societies of psychologists, psychotherapists, and psychoanalysts. Data was collected using semi-structured individual interviews. The interviews were analyzed using interpretative phenomenological analysis (IPA), which allowed for a dynamic exploration of the participants' experiences. A total of 44 participants were interviewed, with 15 interviews specifically focusing on Lebanese psychoanalysts and psychotherapists.
Results
Our study revealed four superordinate themes: (1) the strained frontiers; (2) the cumulative traumatic reality and its impact; (3) A challenged professional identity; (4) The creativity stemming from collective trauma.
Conclusions
Our results highlight the insecurity caused by external reality infiltrating the therapeutic setting. Online therapy allowed for continued work, but uncertainty about the online environment's impact on therapeutic relationships was observed. The study underscores the importance of adaptability, containment, and support for therapists navigating crises, particularly in the online setting.
Terahertz based optical &amp; electrical properties of PZT
Authors: Yadagiri K. , Nagaraju M. , Reddy V. Raghavender , Chaudary A. K. , Dinkar D. , Kumar K. Uday , Haranath D. 
Published: July 2023

Abstract

Piezoelectric materials have been using widely for various applications like MEMS and energy harvesting. The PZT (PbZr0. 52Ti0.48O3) is one among of all piezoelectric materials, which exhibit vital role for fabrication of devices. The present manuscript is described about PZT powders, which were synthesized by solgel method and yielded powders were annealed at different temperature to get stabilize structure without any impurities phase with help of X-ray diffraction. As a part of structural investigation, Raman spectroscopy have done over the different temperature annealed powders and identify Raman active modes. The band gap energy was found for these nano powders that are increasing with respect to annealing temperature. The microstructure of nano PZT powders has found with help FESEM, which provided the particles size with order of 50-70 nm diameters. Electrical properties i.e., the P-E loop have done on nano PZT, polarization has increased and leakage current also increased for annealed temperatures. The terahertz spectra of PZT results suggested that the absorption coefficient peak found at higher frequency, refractive index peak found lower frequency for annealed PZT samples. The 600oC is shown maximum dielectric constant & refractive index at 0.6 THz, which is confirmed by the electric properties of PZT. As annealing temperature increases, dielectric and refractive index decreased due to depolarization.
Enhancing the quality of lentil proteins via combination with whey proteins based on a dual process: A novel strategy through the incorporation of complexation and fermentation
Authors: Alrosan Mohammad , Tan Thuan-Chew , Easa Azhar Mat , Gammoh Sana , Alu’datt Muhammad H. , Kubow Stan , Almajwal Ali Madi , Mahmood Ammar A. Razzak , Al-Qaisi Ali 
Published: July 2023

Abstract
In recent years, there has been a growing interest in developing a distinguished alternative to human consumption of animal-based proteins. The application of lentil proteins in the food industry is typically limited due to their poor solubility and digestibility. An innovative method of balancing lentil-whey protein (LP-WP) complexes with higher-quality protein properties was established to address this issue, which coupled a pH-shifting approach with fermentation treatment. The results showed that microorganisms in the water kefir influenced the quality of protein structures and enhanced the nutritional values, including increasing the total phenolic compounds and improving the flavor of fermented LP-WP complexes. The protein digestibility, pH values, microbial growth, total soluble solids, and total saponin and phenolic contents were hydrolyzed for five days at 25 ºC. The FTIR spectrophotometer scans indicated significant (P<0.05) changes to the secondary protein structure components (random coil and α-helix). This study showed that combining pH-shifting with fermentation treatment improves lentil and whey proteins’ structure, protein quality, and nutritional benefits.
Multi-Faceted Attributes of Salivary Cell-free DNA as Liquid Biopsy Biomarkers for Gastric Cancer Detection
Authors: Swarup Neeti , Cheng Jordan , Choi Irene , Heo You Jeong , Kordi Misagh , Li Feng , Aziz Mohammad , Chia David , Wei Fang , Elashoff David , Zhang Liying , Kim Sung , Kim Yong , Wong David T.W. 
Published: July 2023

Abstract
Background
Recent advances in circulating cell-free DNA (cfDNA) analysis from biofluids have opened new avenues for liquid biopsy (LB). However, current cfDNA LB assays are limited by the availability of existing information on established genotypes associated with tumor tissues. Certain cancers present with a limited list of established mutated cfDNA biomarkers, and thus, nonmutated cfDNA characteristics along with alternative biofluids are needed to broaden the available cfDNA targets for cancer detection. Saliva is an intriguing and accessible biofluid that has yet to be fully explored for its clinical utility for cancer detection.
Methods
In this report, we employed a low-coverage single stranded (ss) library NGS pipeline "Broad-Range cell-free DNA-Seq" (BRcfDNA-Seq) using saliva to comprehensively investigate the characteristics of salivary cfDNA (ScfDNA). The identification of cfDNA features has been made possible by applying novel cfDNA processing techniques that permit the incorporation of ultrashort, ss, and jagged DNA fragments. As a proof of concept using 10 gastric cancer (GC) and 10 noncancer samples, we examined whether ScfDNA characteristics, including fragmentomics, end motif profiles, microbial contribution, and human chromosomal mapping, could differentiate between these two groups.
Results
Individual and integrative analysis of these ScfDNA features demonstrated significant differences between the two cohorts, suggesting that disease state may affect the ScfDNA population by altering nuclear cleavage or the profile of contributory organism cfDNA to total ScfDNA. We report that principal component analysis integration of several aspects of salivary cell-free DNA fragmentomic profiles, genomic element profiles, end-motif sequence patterns, and distinct oral microbiome populations can differentiate the two populations with a p value of < 0.0001 (PC1).
Conclusion
These novel features of ScfDNA characteristics could be clinically useful for improving saliva-based LB detection and the eventual monitoring of local or systemic diseases.
Efficacy and Saffety of a Topical Natural Cream to Psoriasis:
Randomized Clinical Trial
Authors: Benites Elizabeth , Carrillo Esmeralda , Heras Martha , Bourne Doménica 
Published: July 2023

Abstract
Introduction: Psoriasis is an inflammatory skin disease. The objective of this study was to evaluate the effectiveness and efficacy of a natural topical cream and compare it with the gold-standard topical cream.
Methodology: Randomized clinical trial, in 100 healthy volunteer subjects, five formulations of the new product were prepared and applied to 20 healthy subjects for each formulation. Of the 270 patients with psoriasis, 120 volunteer patients were selected; 60 patients were randomly administered the full natural product, and as a control group, 60 patients were treated with corticosteroid cream at the TMC Hospital.
Outcome: Application in 100 healthy subjects showed that 99% had no side effects. When applied to patients with psoriasis at the TMC Hospital, the response was evaluated 10 days after treatment by comparing the results with a corticosteroid. Categorical variables are expressed as frequencies and percentages, and differences were analyzed using Pearson's chi-square test. Using Student’s t-test for paired tests, the differences before and after treatment between the medians of the continuous variables were analyzed and found to be significant. The distribution of the variables was analyzed using the nonparametric Mann-Whitney U test with the clinical variables, as well as with the PASI index and SBA, resulting in a highly significant P value of 0.000, which showed that the topical natural cream was effective in reducing the characteristic clinical signs in the skin of patients with psoriasis.
Discussion: The application of the new natural cream with anti-inflammatory, exfoliating, soothing, disinfectant, antimicrobial, and healing properties showed that 99% of healthy subjects and patients had no side effects, presenting a rapid, statistically significant efficacy, whose results were compared with a topical corticosteroid 10 days after treatment. The new natural topical cream showed a remitting effect in the third month after the control. This cream was approved for commercialization in February 2023 by the Regulatory and Health Control Agency of Ecuador (ARCSA). As it is effective and efficient in patients with plaque psoriasis and its components are of natural origin, its application is recommended in this type of immunological disease whose improvement was clinically manifested from the beginning of the treatment.
Is Triggering Receptor Expressed On Myeloid Cells 1 (TREM-1) protein a new marker of serious infectious complications in colorectal surgery? – case-matched pilot study
Authors: Pisarska-Adamczyk Magdalena , Rzepa Anna , Kapusta Maria , Zawadzka Karolina , Kuśnierz-Cabala Beata , Wysocki Michał , Małczak Piotr , Major Piotr , Zub-Pokrowiecka Anna , Wierdak Mateusz , Pędziwiatr Michał 
Published: July 2023

Abstract
Purpose
The purpose of the study was to evaluate the usefulness of the Triggering Receptor Expressed On Myeloid Cells 1 (TREM-1) protein as a marker for serious infectious complications during laparoscopic colorectal surgery.
Methods
64 patients with colon or rectal cancer, who underwent an elective laparoscopic colorectal cancer surgery from November 2018 to February 2020, were included in the analysis. Blood samples of the TREM-1 protein testing were collected four times from each patient: before and on three following postoperative days (PODs). Patients were divided into two groups according to the presence of infectious complications. Subsequently, patients with infectious complications (group 1) were matched 1:1 with patients without complications (group 2). The case-matched analysis was done by selecting patients from the control group by age, ASA scale, cancer stage, and type of surgery.
Results
There was no significant difference in demographic and operative characteristics between the two groups. The median length of hospital stay was longer in Group 1 than in Group 2 (11 days vs. 5 days, p<0.001). Preoperative measurements of TREM-1 protein did not differ between the two groups. There were no significant differences in the measurements on the first and third postoperative days. However, the median TREM-1 measurement was higher in Group 1 on the second postoperative day (542 pg/ml vs. 399 pg/ml; p=0.040). The difference was more apparent when only severe postoperative complications were considered. When compared to the group without any complications, the median TREM-1 level was significantly higher in the group with severe infection complications in POD 1, POD 2, and POD 3 (p<0.05). The receiver operating characteristic (ROC) curve demonstrated that TREM-1 readings in 2 POD had sensitivity of 83% and specificity of 84% for the presence of severe infection complications at a value of 579.3 pg/ml (AUC 0.8, 95%CI 0.65-0.96).
Conclusion
TREM-1 measurements might become a helpful predictive marker in the early diagnosis of serious infectious complications in patients following laparoscopic colorectal surgery.
Trial registration number: NCT05933408, date of registration: 6 July 2023, retrospectively registered
Efficient mercury removal and neutralization of wastewater using European beech charcoal
Authors: Udjilanovic Marina , Krstic Vesna , Ciric Andrija 
Published: July 2023

Abstract
This investigation aimed to produce, characterize, and apply European beech (Fagus silvatica) charcoal for wastewater treatment. The results showed that beech charcoal has high thermal stability and carbon content. Elemental analysis results indicated that beech charcoal has a high potassium content. The surface of beech charcoal was rough. The morphology from scanning electron microscope (SEM) images demonstrated that beech charcoal is a highly porous material, with small cavities connected to large cavities. Beech charcoal was worked as an adsorbent for wastewater treatment from the Borska river. The results indicated that beech charcoal could efficiently remove mercury and neutralize the pH of wastewater in wastewater with high acidity and alkalinity.
Heavy metals contamination assessment in the top soils for urban and industrial areas, Semnan, Iran
Authors: Mollashahi Maryam , Feizi Vahid 
Published: July 2023

Abstract
This study was performed using Magnetometery susceptibility (MS) and heavy metal analysis on 36 soil samples at the depth of 0–10 cm collected from urban and industrial areas of Semnan, Iran. The magnetic susceptibility of soil samples were measured by MFK1-A Kappabridge and total metal content such as Pb, Cu, Cr, Cd and Zn were determined by ICP set in the lab of Geological survey and mineral exploration of Iran. The results showed the maximum Magnetic Susceptibility of 317.3 *10− 8 m3/kg which measured in the east of Semnan city. Furthermore, high magnetic susceptibility were obtained on samples from north, East and industrial area of Semnan city (average 285.4*10− 8, 275.6*10− 8 and 261.7*10− 8 m3/kg, respectively) whereas lower susceptibility values were observed in the West area of Semnan city (average 66.1*10− 8,). Heavy metals such as As, Co, Cr, Mn and Zn show a highly significant correlation with magnetic susceptibility. Cd, Cr, Pb and Zn through investigated heavy metals, showed the higher concentrations than pollution threshold values.
The first molecular detection of Coxiella burnetii in blood samples of turtles (T. graeca) and their associated ticks Running Title: Coxiella burnetii in turtle and ticks
Authors: Khademi Peyman , Tukmechi Amir , Ownagh Abdulghaffar , Enferadi Ahmad , Hadian Mojtaba 
Published: July 2023

Abstract
Coxiella burnetii can cause the zoonotic disease of Q fever, which has been recorded in numerous distinctive species. Hyalomma aegyptium can be classified as a hard-tick completing its life cycle through three hosts. Epidemiologically, the spread of pathogens by H. aegyptium between different hosts can be critical. The objective of the present investigation was to detect C. burnetii in blood samples of turtles and H. aegyptium ticks attached to them in northwest of Iran (Oshnavieh). A total of 500 engorged mature ticks and 100 blood samples were obtained from 100 tortoises. A nested-PCR targeting IS1111 and icd genes with specific primers were used to diagnose C. burnetii. From 100 tick pool samples based on IS1111 gene, 10 were infected with C. burnetii (10%; 95% CI: 5.5–17.4). The rate of infection with C. burnetii based on the icd gene in tick samples was 6%; 95% CI: 2.8%-12.5%. In addition, the level of contamination of turtle blood with C. burnetii based on the IS1111 gene was 5%; 95% CI: 2.2%-11.2%. The contamination rate of the blood based on icd gene was 3%; 95% CI: 1%-8.5%. In conclusion, infected tortoises and H. aegyptium ticks with C. burnetii may play a vital part in the transmission of this pathogenic agent to both human and other animals. Additionally, appropriate public health measures should be implemented to decrease the circulation of the pathogen between various hosts.
Immunofluorescence study of cytoskeleton in endothelial cells induced with malaria sera
Authors: Wongsawat Mathusorn , Glaharn Supattra , Sris Charit , Dechkhajorn Wilanee , Chaisri Urai , Punsawad Chuchard , Techarang Tachpon , Chotivanich Kesinee , Krudsood Srivicha , Viriyavejakul Parnpen 
Published: July 2023

Abstract
Background Endothelial cells (ECs) play a major role in malaria pathogenesis, as a point of direct contact of parasitized red blood cells to the blood vessel wall. The study of cytoskeleton structures of ECs, whose main functions are to maintain shape and provide strength to the EC membrane is important in determining the severe sequelae of Plasmodium falciparum malaria. The work investigated the cytoskeletal changes (microfilaments- actin, microtubules- tubulin and intermediate filaments- vimentin) in ECs induced by malaria sera (P. vivax, uncomplicated P. falciparum and complicated P. falciparum).Methods Morphology and fluorescence intensity of EC cytoskeleton stimulated with malaria sera were evaluated using immunofluorescence technique. Control experimental groups included ECs incubated with media alone and with normal sera. Experimental groups consisted of ECs incubated with malaria sera from P. vivax, uncomplicated P. falciparum and complicated P. falciparum. Morphological scores of cytoskeletal alterations and fluorescence intensity were compared across each experiment groupResults The four morphological changes of cytoskeleton included (1) shrinkage of cytoskeleton and ECs with cortical condensation, (2) appearance of eccentric nuclei, (3) presence of “spiking pattern” of cytoskeleton and EC membrane, and (4) fragmentation and discontinuity of cytoskeleton and ECs. Significant damages were noted in actin filaments compared to tubulin and vimentin filaments in ECs stimulated with sera from complicated P. falciparum malaria. Fluorescence intensity of EC cytoskeleton was also highest in ECs stimulated with sera from complicated P. falciparum malaria and was correlated with morphological damages to cytoskeleton.Conclusions ECs stimulated with sera from complicated P. falciparum malaria showed cytoskeletal alterations and increased in fluorescence intensity. Cytoskeletal changes of ECs incubated with complicated P. falciparum malaria sera can lead to EC junctional alteration and permeability changes, which is mediated through apoptotic pathway. The findings can serve as a basis to explore measures to strengthen EC cytoskeleton and alleviate severe malaria complications such as pulmonary oedema and cerebral malaria. In addition, immunofluorescence intensity of cytoskeleton could be investigated as potential prognostic indicator for malaria severity.
Vertical transmission of gut bacteria in commercial chickens is limited
Authors: Shterzer Naama , Rothschild Nir , Sbehat Yara , Dayan Jonathan , Eytan Dor , Uni Zehava , Mills Erez 
Published: July 2023

Abstract
The existence of vertical transmission in chickens under commercial settings, where chicks are raised separated from adults, is unclear. To answer this question, the fecal microbiota of chicks hatched and grown separately was compared with their mothers’ microbiota. Most amplicon sequence variants (ASVs) identified in hens did not appear at all in chicks up to two weeks of age, and those that did appear had a low incidence among the chicks. Nevertheless, a few ASVs that were common with the hens were highly prevalent among the chicks, implying they were efficiently transmitted to chicks. These ASVs were culturable from the reproductive tract of hens and eggshells. Furthermore, interventions attempting to disrupt transmission resulted in a reduction of prevalence in chicks. To conclude, vertical transmission in commercial poultry grown separately from adults likely exists but is not efficient, possibly resulting in impairment of microbiota function. This implies that artificial exposure to adult bacterial strains might improve microbiota functioning.
Enabling Explainable Artificial Intelligence To Narrate Patent Scenarios in Devising Science Policy Decisions &amp; Technology Forecasts
Authors: Hasan Zeba , Alam M Afshar , Kaur Harleen , Khan Ihtiram Raza , Alankar Bhavya 
Published: July 2023

Abstract
Machine learning methods, offering unique characteristics for variable identification and it’s importance, are now gradually used for prediction, forecasting and devising important scenarios for integral decision-making. Sequential and dynamic growth in technology can fundamentally become a foremost indicator in measuring technology strength in innovative technology-based development. Prudent and systematic data generation is part of the same transition phase playing an equivalent role in creating evidence analysis and service/product development. Assisted solutions of machine learning provide data-driven prediction at core level areas of medical analysis, fraud detection & disease detection, etc. to predict solutions with explainable intelligence. Assisting solutions with more data-driven explainable solutions, during performance of advanced machine learning has created an advanced methodology of generating white box solutions out of the black box interpretation. Explainable artificial intelligence, which gives superior and solution-based AI is not only providing optimal solutions but also provides an impactful decision-making solution. The approach of explainable artificial intelligence being used here represents and mediate assessment for ML algorithms to predict accurate results. Innovation and development, whereby can be identifies via the various innovation indicators, where patents are one of the important solution providers on way for futuristic technology and innovation solution. Patent expansion potentials have been initially proposed by prediction and forecasting of patents, to be considered in identifying technology trends and improving policy decision-making. Now in this paper standardised use of patent values extracted from Organisation for Economic Cooperation and Development (OECD) database of patents for India have been taken to represent technological mandate.