bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rereading entrepreneurial failure from the scientific literature: A bibliometric approach
Authors: Tessier Luc , Ramadan Maarouf , Renaud Alexandre 
Published: July 2023

AbstractAcademic literature analyzing the conditions of entrepreneurial failure has emerged in the last decade. Failure can be interpreted in several ways: failure as the disappearance of the firm, failure based on flawed strategies, organizational failure, and failure defined by the entrepreneur's perception. We mobilize a bibliometric technique and identify different scientific conversations initiated between 2016 and 2021. We conducted a bibliometric study using the bibliographic linkage method on 198 articles. This article is divided into three sections. First, we review the methodological choices made, then we describe the results before discussing their generic implications for understanding the phenomenon of failure.
Electron Transport through Hydrogen Bonded Single‐Molecule Junctions†
Authors: Fang Jiu‐Hong , Zhao Zhi‐Hao , Li Ang‐Xuan , Wang Lin 
Published: July 2023

Comprehensive SummaryHydrogen bonding is a vital driving force for organizing the hierarchy of molecular structure, especially in biologic field. Due to its directionality, selectivity and moderate strength, hydrogen bonding has been extensively introduced into the molecular recognition, sensing and electronic devices. Electric measurements at single‐molecule level facilitate the investigation of hydrogen bonds and provide a comprehensive understanding of the electron transport properties governed by the hydrogen bonding, which is essential for the development of self‐assembled electronic systems. This review provides a detailed overview of recent advancements in constructing single‐molecule junctions utilizing intramolecular and intermolecular hydrogen bonding. We first introduce the methods utilized for characterizing the electric and dynamic properties of non‐covalent interactions. Next, we discuss the mechanisms of electron transport, relevant influencing factors, and typical applications utilizing electrical signals based on single‐molecule junctions. Finally, we propose our perspective on the existing challenges and prospective opportunities in utilizing hydrogen bonding for electronic device applications.
Predictive value of CHA2DS2‐VASc score for in‐hospital prognosis of patients with acute ST‐segment elevation myocardial infarction undergoing primary PCI
Authors: Sun Ying , Ren Jian , Wang Wei , Wang Chunsong , Li Li , Yao Hengchen 
Published: July 2023

AbstractBackgroundThis study aimed to explore the predictive value of CHA2DS2‐VASc score for in‐hospital major adverse cardiac events (MACEs) in ST‐elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary artery intervention.MethodsA total of 746 STEMI patients were divided into four groups according to CHA2DS2‐VASc score (1, 2–3, 4–5, >5). The predictive ability of the CHA2DS2‐VASc score for in‐hospital MACE was made. Subgroup analysis was made between gender differences.ResultsIn a multivariate logistic regression analysis model including creatinine, total cholesterol, and left ventricular ejection fraction, CHA2DS2‐VASc score was an independent predictor of MACE as a continuous variable (adjusted odds ratio: 1.43, 95% confidence interval [CI]: 1.27–1.62, p < .001). As a category variable, using the lowest CHA2DS2‐VASc score of 1 as a reference, CHA2DS2‐VASc score 2–3, 4–5, >5 groups for predicting MACE was 4.62 (95% CI: 1.94–11.00, p = .001), 7.74 (95% CI: 3.18–18.89, p < .001), and 11.71 (95% CI: 4.14–33.15, p < .001). The CHA2DS2‐VASc score was also an independent risk factor for MACE in the male group, either as a continuous variable or category variable. However, CHA2DS2‐VASc score was not a predictor of MACE in the female group. The area under the curve value of the CHA2DS2‐VASc score for predicting MACE was 0.661 in total patients (74.1% sensitivity and 50.4% specificity [p < .001]), 0.714 in the male group (69.4% sensitivity and 63.1% specificity [p < .001]), but there was no statistical significance in the female group.ConclusionsCHA2DS2‐VASc score could be considered as a potential predictor of in‐hospital MACE with STEMI, especially in males.
Fractional modeling of drug diffusion from cylindrical tablets based on Fickian and relaxed approaches with in vivo validation
Authors: Khalaf M. , Elsaid A. , Hammad S. F. , Zahra W. K. 
Published: July 2023

AbstractMathematical simulation of drug diffusion is a significant tool for predicting the bio‐transport process. Moreover, the reported models in the literature are based on Fick's approach, which leads to an infinite propagation speed. Consequently, it is essential to construct a mathematical model to represent the diffusion processes for estimating drug concentrations at different sites and throughout the circulation. Thus, in this article, the diffusion process is employed to propose three models for estimating the drug release from multi‐layer cylindrical tablets. A fractional model is presented based on Fick's approach, while classical and fractional Cattaneo models are presented using the relaxed principle. Various numerical methods are used to solve the specified problem. The numerical scheme's stability and convergence are demonstrated. Drug concentration and mass profiles are presented for the tablet and the external medium and compared with the in vivo plasma profiles. The results show the efficiency and precision of the proposed fractional models based on the fourth‐order weighted‐shifted Grünwald–Letnikov difference operator approximation. These models are compatible with the in vivo data compared with the classical Fick's one.
Regulating Plant Growth in Cotton
Authors: Lee Joshua , Snider John L. , Parkash Ved , Virk Gurpreet , Hand Lavesta C. 
Published: July 2023

AbstractTall cotton plants do not necessarily produce maximum yields or quality. Growth‐promoting field conditions in the absence of chemical growth control can produce cotton plants that are extremely tall but exhibit excessive vegetative growth at the expense of reproductive growth. Cotton producers must often consider incorporating plant growth regulators (PGRs) as a part of their management decisions during the growing season. The focus of article is on the use of the PGR mepiquat chloride and the role of production environment, cultivar, and other management considerations. Earn 0.5 CEUs in Crop Management by reading this article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
Exploring behavioral phenotypes in a mouse model of fetal alcohol spectrum disorders
Authors: Chaudoin Tammy R. , Bonasera Stephen J , Dunaevsky Anna , Padmashri Ragunathan 
Published: July 2023

AbstractFetal alcohol spectrum disorders are one of the leading causes of developmental abnormalities worldwide. Maternal consumption of alcohol during pregnancy leads to a diverse range of cognitive and neurobehavioral deficits. Although moderate‐to‐heavy levels of prenatal alcohol exposure (PAE) have been associated with adverse offspring outcomes, there is limited data on the consequences of chronic low‐level PAE. Here, we use a model of maternal voluntary alcohol consumption throughout gestation in a mouse model to investigate the effects of PAE on behavioral phenotypes during late adolescence and early adulthood in male and female offspring. Body composition was measured by dual‐energy X‐ray absorptiometry. Baseline behaviors, including feeding, drinking, and movement, were examined by performing home cage monitoring studies. The impact of PAE on motor function, motor skill learning, hyperactivity, acoustic reactivity, and sensorimotor gating was investigated by performing a battery of behavioral tests. PAE was found to be associated with altered body composition. No differences in overall movement, food, or water consumption were observed between control and PAE mice. Although PAE offspring of both sexes exhibited deficits in motor skill learning, no differences were observed in basic motor skills such as grip strength and motor coordination. PAE females exhibited a hyperactive phenotype in a novel environment. PAE mice exhibited increased reactivity to acoustic stimuli, and PAE females showed disrupted short‐term habituation. Sensorimotor gating was not altered in PAE mice. Collectively, our data show that chronic low‐level exposure to alcohol in utero results in behavioral impairments.
Citizen science data reveal regional heterogeneity in phenological response to climate in the large milkweed bug, Oncopeltus fasciatus
Authors: Garretson Alexis , Cuddy Tedra , Duffy Alexandra G. ,   iNaturalist Citizen Scientists, Forkner Rebecca E. 
Published: July 2023

AbstractRegional populations of geographically widespread species may respond to different environmental factors across the species' range, generating divergent effects of climate change on life‐history phenology. Using thousands of citizen science observations extracted from iNaturalist and associated with corresponding temperature, precipitation, elevation, and daylength information, we examined the drivers of adult mating and of nymphal phenology, development, and group size for populations of the large milkweed bug, Oncopeltus fasciatus, in different ecoregions. Research‐grade iNaturalist images were correctly identified 98.3% of the time and yielded more than 3000 observations of nymphal groups and 1000 observations of mating adults spanning 18 years. Mating phenology showed distinct regional patterns, ranging from year‐round mating in California to temporally restricted mating in the Great Lakes Northeastern Coast ecoregion. Relative temperature increases of 1°C for a given daylength expanded the mating season by more than a week in western ecoregions. While increases in relative temperature delayed mating phenology in all ecoregions, greater winter precipitation advanced mating in the California ecoregion. In the eastern ecoregions, nymphal phenology was delayed by increases in summer rainfall but was advanced by relative temperature increases, whereas in western regions, relative temperature increases delayed nymphal phenology. Furthermore, accumulated growing degree days (AGDD) was a poor predictor of developmental progression, as we found a positive but weak correlation between AGDD and age structure only for the Appalachian Southeast North America and the Great Lakes Northern Coast ecoregions. These complex phenological responses of O. fasciatus are just one example of how populations may be differentially susceptible to a diversity of climatic effects; using data across a species' whole distribution is critical for exposing regional variations, especially for species with large, continental‐scale ranges. This study demonstrates the potential of photodocumented biodiversity data to aid in the monitoring of life history, host plant–insect interactions, and climate responsiveness.
Surface and subsurface oceanographic features drive forage fish distributions and aggregations: Implications for prey availability to top predators in the US Northeast Shelf ecosystem
Authors: Goetsch Chandra , Gulka Julia , Friedland Kevin D. , Winship Arliss J. , Clerc Jeff , Gilbert Andrew , Goyert Holly F. , Stenhouse Iain J. , Williams Kathryn A. , Willmott Julia R. , Rekdahl Melinda L. , Rosenbaum Howard C. , Adams Evan M. 
Published: July 2023

AbstractForage fishes are a critical food web link in marine ecosystems, aggregating in a hierarchical patch structure over multiple spatial and temporal scales. Surface‐level forage fish aggregations (FFAs) represent a concentrated source of prey available to surface‐ and shallow‐foraging marine predators. Existing survey and analysis methods are often imperfect for studying forage fishes at scales appropriate to foraging predators, making it difficult to quantify predator–prey interactions. In many cases, general distributions of forage fish species are known; however, these may not represent surface‐level prey availability to predators. Likewise, we lack an understanding of the oceanographic drivers of spatial patterns of prey aggregation and availability or forage fish community patterns. Specifically, we applied Bayesian joint species distribution models to bottom trawl survey data to assess species‐ and community‐level forage fish distribution patterns across the US Northeast Continental Shelf (NES) ecosystem. Aerial digital surveys gathered data on surface FFAs at two project sites within the NES, which we used in a spatially explicit hierarchical Bayesian model to estimate the abundance and size of surface FFAs. We used these models to examine the oceanographic drivers of forage fish distributions and aggregations. Our results suggest that, in the NES, regions of high community species richness are spatially consistent with regions of high surface FFA abundance. Bathymetric depth drove both patterns, while subsurface features, such as mixed layer depth, primarily influenced aggregation behavior and surface features, such as sea surface temperature, sub‐mesoscale eddies, and fronts influenced forage fish diversity. In combination, these models help quantify the availability of forage fishes to marine predators and represent a novel application of spatial models to aerial digital survey data.
Pore and gas desorption characteristics of primary coal with different degrees of metamorphism
Authors: Chen Yong , Liu Ronghua , Wang Gang , Ma Jinkui , Wu Jiaokun , Wang Pengfei , Wu Kuan , Guo Xiaomin 
Published: July 2023

AbstractPore difference characteristics and adsorption/desorption experiments of primary coal with different degrees were explored to study the characteristics of pore structure and gas desorption. The results show that the pore volume increases with the increase in the degree of metamorphism. In primary coal with different degrees of metamorphism, the distribution of micropores, small pores, and medium‐sized pores (by volume) is WY < PM < CY. The distribution of large pore volume and visible pore volume was WY > PM > CY. According to the pore volume distribution law of different metamorphic primary coals, the average pore diameters of WY, PM, and CY were 68.40, 45.60, and 30.50 nm, respectively. The porosity and specific surface area of primary coal with different degrees of metamorphism show a distribution pattern such that WY > PM > CY. For large pore and visible pore, the pore volumes of WY, PM, and CY coal were 0.0785, 0.0587, and 0.0300 mL/g, respectively, and the proportions were 81.86%, 74.49%, and 55.25%, respectively. The porosity of WY, PM, and CY were 11.57%, 9.03%, and 6.57%, respectively, and the specific surface areas were 6.917, 5.826, and 5.611 cm3/g. According to the desorption characteristics of coal bodies with different metamorphic degrees at different time nodes found that the gas desorption at different time nodes shows similar changes under the same adsorption equilibrium pressure. The higher the degree of coal metamorphism, the greater the amount of gas desorption, and the faster the desorption amplitude. The desorption intensity of WY coal is significantly higher than that of PM and CY coal with the increase of desorption time which also verifies the measurement results of pore structure and adsorption constant.
Maternal Transfer and Effects of Selenium on Early Life Stage Development of Redside Shiner (Richardsonius balteatus)
Authors: de Bruyn Adrian M. H. , Lo Bonnie P. , Van Geest Jordana , Semeniuk David , Elphick James R. , Ings Jennifer , Good Cait , Arnold Mariah C. , Brix Kevin V. 
Published: July 2023

Abstract
Maternal transfer of selenium (Se) to developing fish eggs during vitellogenesis can cause larval deformity and mortality. Previous studies have shown wide variation among fish species in both the magnitude of maternal transfer (exposure) and the egg Se concentration causing effects (sensitivity). We studied maternal transfer and effects of Se on early life stage development, survival, and growth of redside shiner (Richardsonius balteatus), a small-bodied cyprinid that has been reported to have relatively high ovary:muscle Se concentration ratios. Gametes were collected from lentic areas in southeast British Columbia (Canada) with a range of dietary Se concentrations related to weathering of waste rock from coal mining. Eggs were fertilized and reared in the laboratory from hatch to the onset of exogenous feeding. Larvae were assessed for survival, length, weight, Se-characteristic deformities, and edema. Eggs from a total of 56 females were collected, with egg Se concentrations from 0.7 to 28 mg/kg dry weight. Maternal transfer varied among sites, with egg:muscle Se concentration ratios ranging from &lt;1 to &gt;4. We also found that sampling residual ovaries can overestimate Se concentrations in ripe eggs by up to a factor of 5.7. A correlation between larval weight and egg Se concentration was identified, although the relationship was weak (r2 &lt; 0.1) and appeared to be a site effect. No other relationships were observed between larval endpoints and egg Se concentrations up to the highest concentration tested, indicating that the effects threshold for this species may be &gt;28 mg/kg dry weight in eggs. These data indicate that redside shiner is less sensitive to maternally transferred Se than most other tested fish species. Environ Toxicol Chem 2023;42:2350–2357. © 2023 SETAC
Profile, Tissue Distribution, and Time Trend of Bisphenol Plastic Additives in Freshwater Wildlife of the Pearl River Ecosystem, China
Authors: Peng Xianzhi , Zhou Jing , Chen Guangshi , Tan Jianhua , Zhu Zewen 
Published: July 2023

Abstract
Plastic-related contaminants in the environment have attracted increasing attention, with plastic pollution becoming a serious issue globally. The present study investigated the potential bioaccumulation and biotransfer of bisphenol (BP) compounds that are widely added in various products such as plastics and other products in a freshwater ecosystem, China. Among commonly applied 14 BP analogues, bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS) were predominant, representing 64%–100% of the total concentrations of BPs (ΣBPs) in freshwater wildlife. Both the concentrations and analogue profiles in the fish showed seasonal differences and species dependence. Higher BP concentrations were observed in fish collected during the dry season than the wet season. Higher percentages of non-BPA analogues (e.g., BPS and BPF) were observed in fish collected during the wet season. Pelagic species accumulated notably higher levels of BPs than midwater and bottom species. The liver generally contained the highest ΣBPs, followed successively by the swim bladder, belly fat, and dorsal muscle. The analogue profile also showed some differences among tissues, varying by species and season. Lower ΣBPs but higher percentages of non-BPA analogues were observed in female than male common carp. Time trends of the BPA concentration in fish varied by species, probably related to habitats and diets of the fish. Habitats, feeding behaviors, and trophic transfer may have significant impacts on exposure of wildlife to BPs in natural ecosystems. The BPs did not demonstrate strong potential for bioaccumulation. More research is warranted about metabolism and transgenerational transfer of BPs in wildlife to fully reveal the bioaccumulation and consequently ecological risks of these chemicals in the environment. Environ Toxicol Chem 2023;42:2130–2142. © 2023 SETAC
The potential role of synovial cells in the progression and treatment of osteoarthritis
Authors: Zou Zaijun , Li Han , Yu Kai , Ma Ke , Wang Qiguang , Tang Junnan , Liu Guozhen , Lim Khoon , Hooper Gary , Woodfield Tim , Cui Xiaolin , Zhang Weiguo , Tian Kang 
Published: July 2023

AbstractOsteoarthritis (OA), the commonest arthritis, is characterized by the progressive destruction of cartilage, leading to disability. The Current early clinical treatment strategy for OA often centers on anti‐inflammatory or analgesia medication, weight loss, improved muscular function and articular cartilage repair. Although these treatments can relieve symptoms, OA tends to be progressive, and most patients require arthroplasty at the terminal stages of OA. Recent studies have shown a close correlation between joint pain, inflammation, cartilage destruction and synovial cells. Consequently, understanding the potential mechanisms associated with the action of synovial cells in OA could be beneficial for the clinical management of OA. Therefore, this review comprehensively describes the biological functions of synovial cells, the synovium, together with the pathological changes of synovial cells in OA, and the interaction between the cartilage and synovium, which is lacking in the present literature. Additionally, therapeutic approaches based on synovial cells for OA treatment are further discussed from a clinical perspective, highlighting a new direction in the treatment of OA.
Bioactive peptides: Synthesis, applications, and associated challenges
Authors: Alzaydi Abrar , Barbhuiya Rahul Islam , Routray Winny , Elsayed Abdallah , Singh Ashutosh 
Published: July 2023

AbstractBioactive peptides (BPs) are chains of amino acids linked together by peptide bonds and arranged in a specific way. These peptides are important to human health and can be used in preserving food. The interest in BPs and its benefits has led to increased production from different food sources and advanced technology to extract them in their pure form. This review explores the subject of BP sources, their synthesis, and their application in various fields, including food and pharmaceuticals. Each source has its unique characteristics, types of peptides, and sequences. The sequence of each peptide extracted from different sources differs in their arrangement and effect on disease treatment. Despite the interest in BPs, challenges remain in their fractionation and purification. Further research is needed to fully exploit the potential of this diverse group of compounds for successful future applications.
Assessing changes in potential yields and yield gaps of summer maize in the North China Plain
Authors: Zhang Zemin , Lu Changhe 
Published: July 2023

AbstractIn recent years, China's crop production growth rate has decreased. This has provoked questions on whether the grain yields have reached their potential. Taking the North China Plain (NCP) as the study area, this study first simulated the potential yield of an irrigated maize crop with the WOFOST model, using daily weather data for 1960–2017. The yield gap was quantified for 1998–2017, and finally, the total potential maize production was estimated. The results indicate that during 1960–2017, the average potential yield for the region varied annually from 9.5 to 13.5 t ha−1, showing an obvious downward trend at a rate of 37.6 kg ha−1 per year. The long‐term mean potential yield at all 327 counties ranged from 9.9 to 13.7 t ha−1, increasing from south to north. The annual maize yield gap was between an average of 2.7–6.0 t ha−1 (29.0%–51.3%) of the potential yield for the NCP during 1998–2017. At county‐level, the yield gap varied between 1.9 and 7.8 t ha−1 and exceeded 5.0 t ha−1 for 99 counties (30.3% of all counties). Attainable yields can be increased by 0.1–5.2 t ha−1 at county‐level, and by 2.2 t ha−1 for the whole NCP, implying that the maize production has the potential to increase with 20.8 Mt. To increase maize production, the focus areas should be the southcentral NCP, which have a larger yield gap during 2012–2017.