bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychological distress during pregnancy and adverse maternal and perinatal health outcomes: The role of socioeconomic status
Authors: Daalderop Leonie A. , Lagendijk Jacqueline , Steegers Eric A. P. , El Marroun Hanan , Posthumus Anke G. 
Published: June 2023

AbstractObjectiveTo study the contribution of socioeconomic status (SES) to the prevalence of psychological distress during pregnancy, and to investigate the association between psychological distress and maternal and perinatal health among different SES groups.MethodsThis study was embedded in the Generation R study. Multiple self‐reported questionnaires were used to measure psychological distress. Prevalence differences between SES groups were tested with the χ2 test. Linear and logistic regression analyses were used to examine the associations between psychological distress and maternal and perinatal health outcomes.ResultsWomen of low SES experience symptoms of psychopathology distress 4.5 times as often and symptoms of stress 2.5 times as often as women with of high SES. Women of low SES experiencing symptoms of psychopathology are at greater risk of delivering preterm. We also found associations between psychological distress and adverse perinatal health outcomes among women of middle and high SES.ConclusionThe present study shows that the associations between SES, psychological distress, and maternal and perinatal health are complex, but do exist. To provide a better understanding of these associations, it is important to include mental health information in the standard national data collection on pregnant women, as this allows population‐based studies.
Silymarin modified polysulfone hollow fiber membranes with antioxidant, anti‐M1 macrophage polarization and hemocompatibility for blood purification
Authors: Wang Peichen , Yang Ning , Luo Ying , Wang Gan , Zhou Shuaizhen , Huang Shuai , Chen Li , Zhao Yiping 
Published: May 2023

AbstractOxidative stress is highly prevalent in maintenance hemodialysis patients and increases the risk of cardiovascular morbidity and mortality. Silymarin (SM) is a natural compound extracted from plants, and has been shown to have pharmacological effects such as antioxidant, anti‐inflammatory, cytoprotective, and anti‐nephrotoxicity. SM‐modified polysulfone (PSF) hemodialysis membranes were prepared by an immersion‐precipitation phase transition method. The experimental results showed that the modified membranes effectively scavenged free radicals, significantly inhibited lipid peroxidation, and had good antioxidant stability (60 days). The PSF/SM antioxidant membranes (H‐3) had no pro‐inflammatory effect, which was confirmed by the result of anti‐M1 macrophage polarization. Furthermore, the hemolysis rate (2%), blood cell deformation (3.7%), and inhibition of erythrocyte and platelet adhesion were improved by the SM‐modified PSF membranes. All the results suggest that PSF/SM blended hollow fiber membranes are promising for application in hemodialysis membranes to improve oxidative stress status and reduce inflammation and complications in patients.
Intensified extraction of rare earth elements from coal fly ash
Authors: Lomanjaya Fathony , Liu Jhy‐Chern 
Published: May 2023

AbstractBACKGROUNDThe high demand for coal‐based energy leads to the production of a massive amount of coal fly ash (CFA). Owing to the content of rare earth elements (REEs), CFA is regarded as one of the promising secondary sources of REEs. The corrent study utilized two intensified extraction methods, subcritical water extraction (SWE) and microwave assisted extraction (MAE), in the recovery of REEs, including yttrium (Y) and samarium (Sm), from CFA sample.RESULTSThe effects of acid concentration, temperature, and solid to liquid ratio (S/L), and reaction time on leaching efficiency were investigated. Total of 80.32% of Y and 68% of Sm were leached out using SWE at 1.0 N HCl, S/L of 5 g/L, 150 °C for 5 min. Meanwhile, MAE yielded leaching efficiency of 71.99% of Y and 54.48% of Sm at 2.0 N HCl, S/L of 2.5 g/L, 150 °C for 5 min. Both methods performed better than conventional method.CONCLUSIONSFrom comparisons, SWE showed advantages of higher leaching efficiency at lower acid concentration, while MAE was more rapid and more energy efficient for REEs recovery from CFA. © 2023 Society of Chemical Industry (SCI).
Use of 18F‐FDG PET/MRI as an Initial Staging Procedure for Nasopharyngeal Carcinoma
Authors: Cao Caineng , Fang Yuting , Yu Bocheng , Xu Yuanfan , Qiang Mengyun , Tao Changjuan , Huang Shuang , Chen Xiaozhong 
Published: May 2023

BackgroundCompared with the conventional work‐up (CWU) including computed tomography (CT) of the chest and abdomen, MRI of the head and neck, and skeletal scintigraphy, positron emission tomography (PET)/MRI might improve diagnostic accuracy, shorten the work‐up time, and reduce false‐positive (FP) findings in patients with nasopharyngeal carcinoma (NPC). However, evidence of cost‐effectiveness is needed for the adoption of PET/MRI for the initial staging in NPC.PurposeTo evaluate the cost‐effectiveness and clinical value of PET/MRI as an initial staging procedure for NPC.Study TypeRetrospective cohort cost effectiveness study.SubjectsThree hundred forty‐three patients with a median age of 51 (13–81) years underwent PET/MRI before treatment (the PET/MRI group) and the remaining 677 patients with a median age of 55 (15–95) years only underwent CWU (the CWU group). There were 80 (23.3%) females and 193 (28.5%) females in the PET/MRI and CWU groups, respectively.Field Strength/Sequence3‐T integrated PET/MRI system, diffusion‐weighted echo‐planar imaging (b = 0 and 1000 s/mm2) and [18F] fluorodeoxyglucose PET.AssessmentThe primary end point was the FP rate. Costs were determined as issued in 2021 by the Medical Insurance Administration Bureau of Zhejiang, China.Statistical TestsIncremental cost effectiveness ratio (ICER) measured cost of using PET/MRI per percent of patients who avoided a FP. A P‐value <0.05 was considered statistically significant.ResultsFor the whole group, the de novo metastatic disease rate was 5.2% (53/1020). A total of 187 patients with FP results were observed. Significantly more patients with FP results were observed in the CWU group compared to the PET/MRI group (25.6% vs. 4.1%). The ICER was $54 for each percent of patients avoiding a FP finding.Data ConclusionCompared with CWU, PET/MRI may reduce the FP risk. Furthermore, PET/MRI may be cost‐effective as an initial staging procedure for NPC.Evidence Level3Technical EfficacyStage 6
Multi‐omic and comparative analyses revealed monocyte‐derived alpha‐defensin‐1 correlated with COVID‐19 severity and inhibited SARS‐CoV‐2 infection
Authors: Qian Xijing , Wu Bingan , Chen Xiang , Peng Haoran , Liu Miao , Tang Hailin , Xu Zhengmei , Xu Chen , Qi Zhongtian 
Published: May 2023

AbstractSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the etiological pathogen of coronavirus disease 2019 (COVID‐19), a highly contagious disease, spreading quickly and threatening global public health. The symptoms of COVID‐19 vary from mild reactions to severe respiratory distress or even fatal outcomes probably due to the different status of host immunity against the virus. Here in the study, we unveiled plasma proteomic signatures and transcriptional patterns of peripheral blood mononuclear cells (PBMCs) using blood samples of 10 COVID‐19 patients with different severity. Through systemic analysis, α‐defensin‐1 (DEFA1) was identified to be elevated in both plasma and PBMCs, and correlated with disease severity and stages. In vitro study demonstrated that DEFA1 was secreted from immunocytes and suppressed SARS‐CoV‐2 infection of both original and mutated strains with dose dependency. By using sequencing data, we discovered that DEFA1 was activated in monocytes through NF‐κB signaling pathway after infection, and secreted into circulation to perturb SARS‐CoV‐2 infection by interfering protein kinase C expression. It worked mainly during virus replication instead of entry in host cells. Together, the anti‐SARS‐CoV‐2 mechanism of DEFA1 has unveiled a corner of how innate immunity is against SARS‐CoV‐2 and explored its clinical potential in disease prognosis and therapeutic intervention.
Raman spectroscopic study of non‐stoichiometry in cerianite from critical zone
Authors: Zhukova Irina A. , Stepanov Aleksandr S. , Malyutina Alexandra , Doroshkevich Anna G. , Korsakov Andrey V. , Jiang Shao‐Yong , Bakovets Vladimir V. , Pomelova Tatyana A. , Nigmatulina Elena N. 
Published: June 2023

AbstractCerianite (CeO2) is one of the key minerals controlling the behavior of rare earth elements (REE) in supergene environment, yet little is known about the composition and structure of the mineral. We present Raman spectroscopy and compositional data on regolith cerianite from carbonatite‐related supergene REE deposits. Cerianite showed a low content of impurities, distinguishing from high‐temperature environments, where the mineral is characterized by elevated concentrations of lanthanides other than Ce. The Raman spectra are characterized by the shift of the dominant peak located at 464–465 cm−1 in stoichiometric CeO2 to the lower wavenumbers of 450–455 cm−1, the widening of this peak with the increasing shift, and the presence of additional peaks at 225–230, 284, and 604–613 cm−1. The independence of the main spectral characteristics from the laser wavelength (tested by three lasers: 488, 532, and 633 nm) suggests that the features are genuine and not produced by REE luminescence. The anhydrous composition of supergene cerianite is indicated by the absence of Raman bands in the water‐bearing region of the spectra (2700–3200 cm−1). The spectral features of supergene cerianite, combined with the compositional data, suggest non‐stoichiometry in the mineral and the presence of Ce3+ with oxygen vacancies in the mineral structure. Our observations demonstrate the efficiency of Raman spectroscopy for the identification of the non‐stoichiometric composition of cerianite and its common occurrence in the critical zone.
Assessing food safety risks based on a geospatial analysis: toward a cross‐regional food safety management
Authors: Nie Wenjing , Liu Chunhui 
Published: June 2023

AbstractBACKGROUNDFood safety risks (FSRs) are increasingly characterized by geographical complexity along with rapid urbanization, changing dietary pattern, and the modernization of the food industry. These factors pose challenges for food risk control in developing economies, more so during the global COVID‐19 pandemic. The accurate assessment of risk source and transfer path is a crucial step toward enhancing cross‐regional food safety management. This study aims to examine the spatial distribution, transfer path and driving factors of FSRs in China, provided with a national food safety database collected from 8.63 million batches of food sampling inspections for 33 different types of foods across 30 provinces.RESULTSThe findings reveal significant regional disparities in FSRs, which is the highest in the west with small‐scale sampling inspection and the lowest in the east with intensive sampling inspection. Catering and processed foods with higher daily consumption suffer more profound FSR than agricultural products. As evidenced by the shrinking low‐low agglomeration areas, the local FSRs have been effectively controlled. The high‐high agglomeration areas playing positive impacts on risk control are expanding while distributed discretely.CONCLUSIONThe spatial transfer of FSRs is significantly driven by multiple drivers: regulatory capacity and intensity, information disclosure, food industry, regional economy, and food consumption. Assessing FSRs based on a geospatial analysis contributes to identifying risk sources, optimizing risk management, and constructing a sustainable food safety system. © 2023 Society of Chemical Industry.
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Authors: Zimnicka Magdalena M. 
Published: June 2023

AbstractRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM‐MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM‐MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas‐phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent interactions innate upon the ionization process, have attracted even more attention and gained increasing interest in the scientific community. Thus, various types of supramolecular complexes and assemblies relevant for biological, medical, material, and environmental sciences have been characterized so far by IM‐MS supported by computational chemistry. This review covers the state‐of‐the‐art in this field and discusses experimental methods and accompanying computational approaches for assessing the reliable three‐dimensional structural elucidation of supramolecular complexes and assemblies by IM‐MS.
Demography of Oysters Pre- and Postcollapse in Apalachicola Bay, Florida, Using Stage-Based Counts
Authors: Johnson Fred A. , Camp Edward V. , Gandy Ryan , Pine William E. 
Published: June 2023

Abstract
The collapse of oyster populations and the fisheries they support has been a worldwide phenomenon, but studies of oyster demography in situ prior to and after the collapse have been rare. We used time series of stage-based counts of eastern oysters Crassostrea virginica in Apalachicola Bay, Florida, to help understand how abundance and demographic rates may have changed in the decade after the 2012 collapse relative to the period before the collapse. We relied on a Bayesian hierarchical model in which the latent stage structure of the oyster population (i.e., densities of spat, sublegal oysters, and legal oysters) was governed by a system process and where the count data represented summaries of that latent structure. Count data were sufficient to conduct this on two large oyster bars that had some of the highest precollapse oyster densities. We also examined nine other bars with less data for any temporal trends in postcollapse abundance that might be associated with recent restoration efforts. Among the 11 bars examined, oyster densities were often increasing prior to the collapse and were very low, without detectable trends, afterward. Based on our demographic analyses, mortality rates of Apalachicola Bay oysters in the decade after the collapse generally exceeded (often greatly so) those during the precollapse period for all oyster stages. On the other hand, spat settlement rates apparently were increasing prior to the collapse and remained high during the postcollapse period. Simulations of postcollapse demography suggest that without improved survival rates, further declines of the oyster population can be expected. We discuss these findings in light of ongoing restoration and management efforts and suggest ways in which rapid transitions to undesirable socio-ecological regimes might be avoided in the future.
Sitting may increase risk for radiographic incidence and progression of knee osteoarthritis over 2 years: Data from a large cohort study
Authors: Voinier Dana , Neogi Tuhina , Master Hiral , Thoma Louise M. , Brunette Meredith , Jakiela Jason , Stefanik Joshua J. , White Daniel K. 
Published: May 2023

AbstractObjectivesTo examine the association of leisure‐time sitting with radiographic incidence and progression of knee osteoarthritis (OA) over 2 years, and to determine whether worktime sitting modifies this association.MethodsWe included adults with or at high risk for knee OA who enroled in the Osteoarthritis Initiative (OAI). Participants reported leisure‐time sitting (≤4 vs. >4 h/day) and worktime sitting (frequent vs. infrequent) at enrolment, and had bilateral knee radiographs at enrolment and 2 years later. Our outcome, radiographic knee OA incidence/progression (yes/no), was defined as any increase in Kellgren‐Lawrence grade over 2 years. We examined the association of leisure‐time sitting (≤4 vs. >4 h/day) with risk of radiographic knee OA incidence/progression using binary linear regression, adjusting for potential confounders. We stratified by worktime sitting (frequent vs. infrequent) and repeated our analysis.ResultsWe included 4254 adults (mean age 61 years; 58% women; mean body mass index 29 kg/m2) who contributed a total of 8127 knees. Adults with >4 h/day of leisure‐time sitting had 25% higher risk (adjusted risk ratio [RR] 1.25, 95% confidence interval [95% CI] 1.08–1.50) for radiographic knee OA incidence/progression compared with adults with ≤4 h/day of leisure‐time sitting (referent group). Importantly, this association was intensified (RR 1.60, 95% CI 1.19–2.33) among adults with frequent worktime sitting, but was attenuated (RR 1.11, 95% CI 0.89–1.39) among adults with infrequent worktime sitting.ConclusionsHigher leisure‐time sitting (>4 h/day) may be associated with greater risk for radiographic knee OA incidence/progression over 2 years. Furthermore, this association was intensified among adults who also reported frequent worktime sitting.
Evaluation of the impact of guideline communication from the Centers for Disease Control and Prevention and the Centers for Medicare and Medicaid Services among US healthcare providers: COVID‐19 prevention counselling guidance
Authors: Taylor Melanie M. , Deb Arkaprava , Frazier Bernita , Lueken James Reiss , Das Mansi , Molke Joanna , Fitzgerald Erin , Ullian Tom , Nair Ridhu , Couch Marion , Turbyfill Caitlin , Horter Libby , Joshi Cecilia , DeLuca Nickolas 
Published: May 2023

AbstractAimTo evaluate healthcare provider awareness and uptake of the Centers for Medicare & Medicaid Services (CMS) billing for coronavirus disease 2019 (COVID‐19) prevention counselling and the delivery of prevention counselling to patients awaiting severe acute respiratory syndrome coronavirus 2 test results.DesignCross sectional survey of US‐based healthcare providers in February 2021.MethodsAnalysis of associations with healthcare provider‐reported awareness of CMS prevention counselling guidance and billing with provider type, specialty, and work setting.ResultsA total of 1919 healthcare providers responded to the survey. Overall, 38% (726/1919) of providers reported awareness of available CMS reimbursement for COVID‐19 patient counselling and 29% (465/1614) of CMS billing‐eligible providers reported billing for this counselling. Among physicians, those aware of CMS guidance were significantly more likely to bill (58%) versus those unaware (10%). Among RNSights respondents eligible for CMS billing (n = 114), 31% of those aware of the guidance reported billing as compared to 0% of those not aware.
A quadratic finite element for the relaxed micromorphic model
Authors: Sky Adam , Muench Ingo , Neff Patrizio 
Published: May 2023

AbstractIn this work we discuss the relaxed micromorphic model and implementation details for a full three‐dimensional formulation entailing a quadratic Lagrangian‐Nédélec finite element and appropriate boundary conditions in the discrete setting.The relaxed micromorphic model is a generalized continuum theory with the capacity to capture more complex kinematical behaviour than in the classical Cauchy continua. Such behaviour is commonly found in materials with a pronounced micro‐structure such as porous media and metamaterials. The theory introduces the microdistortion field, encompassing nine additional degrees of freedom for each material point in the continuum, effectively turning each material point into a deformable micro‐body. The uncommon discrete formulation stems from the employment of the Curl operator in the energy functional of the relaxed micromorphic model, thus requiring H(curl)‐conforming finite elements for well‐posedness to be inherited in the discrete setting. The model further introduces the so called consistent coupling condition, which requires some technical considerations in order to be upheld correctly.This work demonstrates the finite element formulation, culminating with a numerical example.
Hydraulically induced fracturing in heterogeneous porous media using a TPM‐phase‐field model and geostatistics
Authors: Wagner Arndt , Sonntag Alixa , Reuschen Sebastian , Nowak Wolfgang , Ehlers Wolfgang 
Published: May 2023

AbstractHydraulically induced fracturing is widely used in practice for several exploitation techniques. The chosen macroscopic model combines a phase‐field approach to fractures with the Theory of Porous Media (TPM) to describe dynamic hydraulic fracturing processes in fully‐saturated porous materials. In this regard, the solid's state of damage shows a diffuse transition zone between the broken and unbroken domain. Rocks or soils in grown nature are generally inhomogeneous with material imperfections on the microscale, such that modelling homogeneous porous material may oversimplify the behaviour of the solid and fluid phases in the fracturing process. Therefore, material imperfections and inhomogeneities in the porous structure are considered through the definition of location‐dependent material parameters. In this contribution, a deterministic approach to account for predefined imperfection areas as well as statistical fields of geomechanical properties is proposed. Representative numerical simulations show the impact of solid skeleton heterogeneities in porous media on the fracturing characteristics, e. g. the crack path.
Thermo‐electrohydrodynamic convection in a differentially heated shell with electric central force field
Authors: Szabo Peter S.B. , Gaillard Yann , Zaussinger Florian , Egbers Christoph 
Published: May 2023

AbstractThermo‐electrohydrodynamic convection is investigated in a shell with central force field to investigate convective pattern formation for potential heat transfer application and small scaled laboratory experiments e.g. the modelling of convection in planetary interiors or atmospheres. To induce TEHD convection the outer and inner shells are heated at different temperatures whereas an alternating electric potential is applied between both shells. The observation of the convective pattern formation suggest that dielectric fluids have a significant response to thermal and electrical forcing. The observed patterns ranged from quasi‐stationary convective modes in azimuthal direction to shape and mode amplitude vacillations with mode merging and separation that are classified into three regimes. The heat transfer was evaluated by the Nusselt number and showed an increase in heat transfer with electric forcing. However, the results indicate a much smaller heat transfer when compared to natural convection.