bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal variation and risk assessment of heavy metals and nutrients from water and sediment in a stormwater pond, Brazil
Authors: da Silva Emanoelle Pereira , Filho Nelson Roberto Antoniosi , Pereira Julião , Martins Formiga Klebber Teodomiro 
Published: December 2022

Abstract
Urban watercourses are under pressure owing to the inflow of environmental pollutants from stormwater and effluent. The concentrations of heavy metals, ammoniacal nitrogen, total phosphorus (TP), and physicochemical parameters were monitored in a sediment pond in the Brazilian Midwest. The correlation between the variables and the degree of sediment contamination was verified using the Geoaccumulation Index (Igeo), Contamination Factor (CF), and Pollutant Load Index (PLI). The general concentrations of the metals were in the order Mn &gt; B &gt; Ba &gt; Zn &gt; Cu &gt; Cr &gt; Pb &gt; Ni in the water and Mn &gt; Cr &gt; Ba ≥ B &gt; Zn &gt; Cu &gt; Ni &gt; Pb in the sediment. The concentrations of Ba, Cr, Cu, Mn, Ni, Pb, and TP in the water exceeded the regulatory limits at least one time. The mean concentrations of Cr, Cu, and Ni in the sediment samples were 6.32, 1.63, and 2.61 higher than standard values. The applied geochemical indices indicated a moderate to a very high degree of sediment contamination, suggesting the anthropogenic origin of Cr, Cu, and Ni. Significant Pearson correlations were observed between turbidity and total suspended solids (TSS), Ba, Cr, Mn, Zn, and TP. Ponds and urban lakes require maintenance or may become a source of environmental pollutants.
Quantitative Ontology and Russian Preposition Database
Authors: Zakharov Viktor , Azarova Irina , Golovina Anastasiya , Gudkov Vadim , Moskvina Anna 
Published: December 2022

Automatic natural language processing that goes beyond the bag-of-words model requires an understanding of semantic and syntactic relationships between language components. This work attempts to address the following issues: 1) describe a set of Russian prepositional structures as an interconnected system; 2) collect corpus-based statistics reflecting preposition meanings and their hierarchy; and 3) describe meanings of prepositions acting as grammatical connectors for content words. Preposition meanings are described using categories based on G. A. Zolotova’s concept of syntaxeme.
The results obtained are based on word frequencies extracted from corpora of contemporary Russian texts. This work describes the key objectives, approaches, methods, novelty, and findings of the research. The key findings include grammar and ontology of the main Russian prepositions, research into secondary prepositions (prepositions derived from content words), preposition database with a network interface, and a set of automated procedures aiding in ‘working out’ the meaning of a preposition.
Bone thickness and height of the buccal shelf area and the mandibular canal position for miniscrew insertion in patients with different vertical facial patterns, age, and sex
Authors: Eto Vitor Mascarenhas , Figueiredo Natália Couto , Eto Luiz Fernando , Azevedo Gabriel Maia , Silva Amaro Ilídio Vespasiano , Andrade Ildeu 
Published: December 2022

ABSTRACTObjectivesThe objectives of this article were the following: (1) to analyze bone thickness and height (BTH) of the buccal shelf area (BS) quantitatively in four different potentially eligible sites for miniscrew insertion; (2) to compare and contrast BTH and the changes in spatial position of the inferior alveolar nerve canal (IANC); and (3) to assess differences with age among vertical facial patterns (hypodivergent, normodivergent, and hyperdivergent) and sex.Materials and MethodsCone-beam computed tomography scans of 205 individuals (110 women and 95 men) were divided into groups according to age, vertical facial pattern, and sex. The BTH of the BS and the BTH to the IANC were measured in the mesial and distal roots of the first and second molars.ResultsBTH progressively increased in a posterior direction (P &lt; .001), while BTH to the IANC increased and decreased (P &lt; .001) for thickness and height, respectively, in the same direction in all age groups, for the three different vertical facial patterns, and in both sexes. Women showed significantly less BTH to the IANC (P &lt; .002). Hypodivergent patients had greater BTH (P &lt; .024) and a smaller bone height to the IANC (P &lt; .018) only in the first molar region. Patients over 40 years of age had lower bone height in the second molar area (P &lt; .003).ConclusionsThe ideal place for BS miniscrew insertion is the region of the distal root of the second molars, regardless of facial pattern, sex, and age. The BS in women has less BTH and less BTH to the IANC.
Two-Year Follow-up From the T1GER Study: Continued Off-Therapy Metabolic Improvements in Children and Young Adults With New-Onset T1D Treated With Golimumab and Characterization of Responders
Authors: Rigby Mark R. , Hayes Beverly , Li Yinglei , Vercruysse Frank , Hedrick Joseph A. , Quattrin Teresa 
Published: December 2022

OBJECTIVEThe T1GER (A Study of SIMPONI to Arrest β-Cell Loss in Type 1 Diabetes) study showed many metabolic benefits of the tumor necrosis factor-α blocker golimumab in children and young adults with type 1 diabetes (T1D). Off-therapy effects are reported.RESEARCH DESIGNS AND METHODST1GER was a phase 2, placebo-controlled, randomized trial in which golimumab or placebo was administered for 52 weeks to participants 6–21 years old diagnosed with T1D within 100 days of randomization. Assessments occurred during the 52-week on-therapy and 52-week off-therapy periods.RESULTSAfter treatment was stopped, C-peptide area under the curve (AUC) remained greater in the treatment versus control group. At weeks 78 and 104, the golimumab group had lower reductions in the 4-h C-peptide AUC baseline than the placebo group, where specifically the golimumab group had reductions of 0.31 and 0.41 nmol/L, and the placebo group had reductions of 0.64 and 0.74 nmol/L. There were also trends in less insulin use, higher peak C-peptide levels and those in partial remission, and higher peak C-peptide levels in the golimumab group. Golimumab responders, defined as having an increase or minimal loss of C-peptide AUC and/or being in partial remission at week 52, showed even greater improvements in most metabolic parameters on and off therapy and had less hypoglycemia during the off-therapy period versus placebo. Adverse events, including infections, were similar between the groups during all time periods of the study.CONCLUSIONSIn children and young adults with new-onset T1D, golimumab preserved endogenous β-cell function and resulted in other favorable metabolic parameters on and off therapy. A subpopulation had disease stabilization while on therapy, with improved metabolic parameters off therapy.
Circulating Small Noncoding RNA Profiling as a Potential Biomarker of Atherosclerotic Plaque Composition in Type 1 Diabetes
Authors: Giannella Alessandra , Castelblanco Esmeralda , Zambon Carlo Federico , Basso Daniela , Hernandez Marta , Ortega Emilio , Alonso Nuria , Mauricio Didac , Avogaro Angelo , Ceolotto Giulio , Vigili de Kreutzenberg Saula 
Published: December 2022

OBJECTIVECardiovascular disease (CVD) accounts for most deaths in patients with type 1 diabetes (T1D); however, the determinants of plaque composition are unknown. miRNAs regulate gene expression, participate in the development of atherosclerosis, and represent promising CVD biomarkers. This study analyzed the circulating miRNA expression profile in T1D with either carotid calcified (CCP) or fibrous plaque (CFP).RESEARCH DESIGN AND METHODSCirculating small noncoding RNAs were sequenced and quantified using next-generation sequencing and bioinformatic analysis in an exploratory set of 26 subjects with T1D with CCP and in 25 with CFP. Then, in a validation set of 40 subjects with CCP, 40 with CFP, and 24 control subjects with T1D, selected miRNA expression was measured by digital droplet PCR. Putative gene targets enriched for pathways implicated in atherosclerosis/vascular calcification/diabetes were analyzed. The patients’ main clinical characteristics were also recorded.RESULTSmiR-503-5p, let-7d-5p, miR-106b-3p, and miR-93-5p were significantly upregulated, while miR-10a-5p was downregulated in patients with CCP compared with CFP (all fold change &gt;±1.5; P &lt; 0.05). All candidate miRNAs showed a significant correlation with LDL-cholesterol, direct for the upregulated and inverse for the downregulated miRNA, in CCP. Many target genes of upregulated miRNAs in CCP participate in osteogenic differentiation, apoptosis, inflammation, cholesterol metabolism, and extracellular matrix organization.CONCLUSIONSThese findings characterize miRNAs and their signature in the regulatory network of carotid plaque phenotype in T1D, providing new insights into plaque pathophysiology and possibly novel biomarkers of plaque composition.
Association between duration of anticoagulant thromboprophylaxis and revision rate in primary total hip arthroplasty: a Danish and Norwegian nationwide cohort study
Authors: Vinther Dennis , Mailhac Aurelie , Andersen Ina Trolle , Overgaard Søren , Lie Stein Atle , Fenstad Anne Marie , Gjertsen Jan-Erik , Furnes Ove , Pedersen Alma B 
Published: December 2022

Background and purpose: There are concerns that bleeding following primary total hip arthroplasty (THA) contributes to prolonged wound drainage and prosthetic joint infection (PJI). We examined whether short (1–5 days), medium (6–14 days), and extended (≥ 15 days) duration of thromboprophylaxis is associated with the 5-year revision rate after THA due to osteoarthritis.Patients and methods: We performed a cohort study based on data from hip arthroplasty and administrative registries in Denmark and Norway (2008–2014). The outcome was revision surgery due to PJI, aseptic loosening or any cause, and patient mortality. Adjusted cause-specific hazard ratios (HRs) were analyzed with Cox regression analyses.Results: Among 50,482 THA patients, 8,333 received short, 17,009 received medium, and 25,140 received extended thromboprophylaxis. The HRs for revision due to PJI within 5 years were 1.0 (95%CI 0.7–1.3) and 1.1 (CI 0.9–1.3) for short and extended vs. medium treatment, whereas HR for extended vs. medium prophylaxis was 1.5 (CI 1.2–2.0) within 3 months. The HRs for revision due to aseptic loosening within 5 years were 1.0 (CI 0.7–1.4) and 1.1 (CI 0.9–1.4) for short and extended vs. medium treatment. The HRs for any revision within 5 years were 0.9 (CI 0.8–1.1) and 0.9 (CI 0.8–1.0) for short and extended vs. medium treatment. Extended vs. medium prophylaxis was associated with a decreased 0–3 month mortality. The absolute differences at 5 years were ≤ 1%.Conclusion: Our data suggests no association between duration of anticoagulant thromboprophylaxis and revision rate within 5 years of primary THA. The extended thromboprophylaxis might be associated with early increased revision rate due to PJI but also with lower mortality; however, the clinical relevance of this finding requires further research.
Animal Viral Diseases Diagnosis In Qatar: Current Situation and Future Prospects
Authors: Enan Khalid A. , Al-Marri Abdulla M. , Al-Zeyara Abdul A. , El Hussein Abdel Rahim M. 
Published: December 2022

Identification and control of viruses that causes diseases in human, domestic and wild animals represent continuous challenges to medical and veterinary sciences. Many diagnostic techniques have for a long time been used to identify individual infectious viral agents by their clinical signs , symptoms and histopathological changes produced in the susceptible host. But it is not always possible to identify or differentiate the disease on the basis of its signs symptoms and pathology, it thus requires use of other specific diagnostic procedures to clearly identify and confirm the pathogens These procedures involve both conventional as well as state of the art techniques. Several conventional techniques such as isolation in cell culture, serology for both antibody and antigen detection are traditionally used to identify viral pathogens. However, the rapid molecular detection techniques of infectious agents in animals as well as in environment have nowadays become an essential part of any modern diagnostic laboratory. Molecular diagnostic technologies are more advantageous as they offer more sensitive, less time consuming, with high throughput results and provide accurate diagnosis and provide thorough understanding of and discrimination of present and emerging diseases. In addition, these new tools can detect the presence of pathogen before the onset of clinical disease. Here we discuss some aspects of the current and contemplated diagnostic tools and their potential applications for diagnosis of viral diseases of domestic and wild animals in Qatar.
Pengembangan Souvenir Wisata Minangkabau Berbasis Human Centered Design di Nagari Kamang Mudiak Kecamatan Kamang Magek Kabupaten Agam Provinsi Sumatera Barat
Authors: Khairani Khairani , Mariya Sri , Putri Sri Kandi , Angraina Dilla 
Published: December 2022

Nagari Kamang Mudiak merupakan salah satu lokasi objek wisata yang belum terekspos secara nasional, yaitu Tarusan Kamang. Namun, masyarakat Nagari Kamang Mudiak belum terlibat langsung dalam pengembangan objek Tarusan Kamang, sehingga wisatawan yang berkunjung hanya datang untuk melihat objek wisata saja. Padahal penting adanya ekonomi kreatif untuk menyuplai permintaan dan kebutuhan wisatawan, salah satunya souvenir wisata. Solusi yang ditawarkan adalah menjadikan Nagari Kamang Mudiak sebagai Nagari Binaan UNP dengan tema Nagari Souvenir Minangkabau atau nagari yang kaya dengan souvenir khas Minangkabau, dengan menggunakan konsep Human Centered Design (HCD). Program yang ditawarkan tersebut sesuai dengan RIP UNP 2016-2020 dengan bidang Pemberdayaan Ekonomi.Kegiatan pelatihan bertujuan untuk meningkatkan minat wirausaha melalui memberikan pelatihan ketarmpilan souvenir wisata minangkabau berbasis human centered design di nagari Kamang Mudiak Kegiatan pengabdian ini dilakukan selama 2 tahun, dimana pada tahun 1 dilakukan pelatihan pembuatan yaitu pembuatan souvenir gantungan kunci dan pin, souvenir gelas, souvenir akrilik objek wisata, souvenir hiasan dinding, souvenir miniatur rumah adat, souvenir dari tempurung, souvenir dari songket dan souvenir miniatur jam gadang. Di samping itu untuk mendesain dan memproduksi kemasan semua produk Nagari Souvenir Minangkabau secara menarik dan memiliki karakteristik yang berbeda. Pada tahun 2, dilakukan promosi dan pemasaran produk yang sudah dibuat selama 1 tahun. Hasil dari pelatihan ini adalah 1) Terciptamya tenaga tenaga yang memliki ketrampilan untuk berwirausaha di bidang souvenir nuansa mingkabau, 2) sebagian peserta pelatihan telah berwirausaha baik melalui online maupun langsung, 3) dibukanya pusat galeri untuk pemasaran produk peserta pelatihan, 4) berdasarkan hasil survey terdapat pengaruh yang signifikan pelatihan ketrampilan terhadap minat wirausaha peserta pelatihan, 5) berdirinya pusat pelatihan ketrampilan bagi masyarakat Kamang Mudiak yang direncanakan kerjasama LP2M UNP dengan nagari Kamang Mudiak.
Advantages of simulative training in practice of practical skills and manipulations of future doctors
Authors: Kozlovska I.M. , Kolotylo O.B. , Kulachek Y.V. , Rusak O.B. , Marusyk U.I. , Smandych V.S. 
Published: December 2022

Relevance. The problem of qualitative training of future doctors is an extremely important issue throughout the world and in Ukraine, including. To improve their practical skills and medical manipulations, they must be brought to ideal and automatism, which is possible due to modern methods of training in the conditions of the simulation center, due to the development of skills on standardized patients and simulators.Objective. To compare the quality of education and working out practical skills, manipulations and evaluate the efficiency of training using patients of medical institutions and mannequins or standardized patients in the center of simulation medicine.Material and methods. We compared the efficiency of working out practical skills, medical manipulations and ability to qualitatively apply them in practice, especially in providing emergency medical care to students of 5 and 6 courses.Results. It is not always possible to immediately establish direct contact with the patient, as opposed to a standardized patient, which extremely accurately demonstrates all complaints and positive symptoms that will allow to confirm the diagnosis. Students are not comfortable with the patient in the clinic or afraid to harm the patient and refuse to survey or conduct a certain skill, while on a mannequin or standardized patient without any fear, a practical skill can be repeated with the required number of times. At a standardized patient or virtual mannequin, a teacher can stop a student at any stage of execution, indicate an error or once again explain the technique of manipulation, and a student may repeat a few times, bringing it to full automatism. Another extremely important advantage of simulating learning is the opportunity at the requested moment, and not when there is a suitable patient in the clinic, to create, simulate and beat the desired situation. This is especially important when working out emergency care skills in conditions that are menacing.
Conclusion. The medical education process must be effective and secure for all participants, specially patients, which is possible only due to simulation centers. Of course, the development of practical skills and manipulations in the simulating center allows to improve traditional types of education, pay more attention to handling skills, allowing, realizing and correcting mistakes, analyze the situation and draw conclusions.
Estudio dogmático del delito de uso indebido de los sistemas telefónicos de emergencia del Código Penal del Estado de Puebla, México
Authors: Nájera González Xavier 
Published: December 2022

El presente trabajo examina los elementos del delito de uso indebido de los sistemas telefónicos de emergencia, tipificado en la legislación penal del Estado de Puebla, México. Así, se inicia con el estudio de los bienes jurídicos protegidos. Luego, se determina la conducta típica, que debe ir impregnada de dolo, pero sobre todo, de dos elementos subjetivos específicos, uno cognoscitivo y otro volitivo, que le imprimen un toque de especificidad a dicha conducta. Todo ello, sin dejar de considerar los medios comisivos en que puede ejecutarse este tipo de injusto. Se finaliza, con el estudio de la punibilidad.
Single-Sided Jacquard Knit Fabric Development and Seamless Ski Underwear Zoning Design based on Body Mapping Sportswear
Authors: Wang Jianping , Zhang Bingjie , Yao Xiaofeng , Shen Jinzhu , Yuan Luning , Pan Ting , Shen Deyao , Li Yupeng 
Published: December 2022

Abstract
In order to meet the functional requirements of professional skiers for ski underwear, such as warmth, breathability, moisture absorption, sweat drainage, and stretch elasticity, six single-sided jacquard knit fabric structures were designed and then knitted with polyester and DRYARN. Then, 12 fabrics were acquired and ranked comprehensively by the one-way analysis of variance and grey correlative analysis based on entropy. According to the fabric properties and sweat distribution on the human skin surface, the professional ski underwear was zoning designed and the wearing experiment and evaluation were carried out on the “Newton” sweated manikin system. The analysis results show that the fabric with DRYARN® material has better air permeability and moisture permeability. Thermal resistance, Clo value, and permeability play important roles in comprehensive evaluation. The results of wearing experiment show that the seamless professional ski underwear woven based on body mapping sportswear has superior function and reasonable design, which can provide technical support for the design of professional seamless ski underwear.
Health Anxiety Among the Normal Population and Healthcare Professionals in a Highly Disadvantaged Region During Three Waves of COVID-19
Authors: Lakatos Csilla , Rucska Andrea 
Published: December 2022

Abstract
Health anxiety manifests in fearing for our health when we recognize factors endangering it. The COVID-19 pandemic has occurred as such a factor in which millions of people have become infected and lost their relatives. The pandemic initiated by an unknown pathogen has occurred as an obviously health-influencing and -threatening phenomenon. The presence of health anxiety related to COVID-19 is considered to be an adaptive reaction, since it strengthens health behaviour (following epidemiological rules, health-protecting behaviour), but its long-lasting, increased level has created problems by influencing more fields of human life in a negative way and inhibiting people seriously in their everyday activities. Our research goal is the assessment of health anxiety among the population of a highly disadvantaged region in North-east Hungary during three waves of the pandemic. We will deal with the health anxiety of healthcare professionals working in this region separately, and we will examine how much the anxiety of people working with seriously ill patients differs from the normal population’s anxiety. This study presents the partial results of the complex mental health image research of the region’s adult population. In this unit of the research, we used the shortened version of the WHO Well-being questionnaire and the Short Health Anxiety Inventory. In the online data recording, 550 persons completed the questionnaire on average. It is not representative, but it reflects the attitude of the region’s population well.
Would Isolationist Presidents Cause War?
Authors: Küntay Ismail Burak 
Published: December 2022

Abstract
In American politics, it has been seen that the presidents, who came to power from an isolationist perspective, contrary to their rhetoric, find themselves in the greatest wars in American History. In this study, it was researched whether the isolationist rhetoric of some Presidents who were sitting in the presidency during the period of the great chaos experienced in the USA and the world resulted in great wars, or whether the discourses that winning the elections to these Presidents should have an isolationist approach as a result of decomposition of the world and reflection of economic problems to their countries. The assumption of this study is that the Presidents who won the elections with their isolationist rhetoric were later faced with major wars during their presidency as a result of the processes that had laid their foundations before they were President and their infrastructure had been formed in the light of developments in the world. In this context, the internal political and international conjuncture of William McKinley, Woodrow Wilson and Franklin D. Roosevelt periods will be evaluated. Accordingly, domestic and foreign policy statements and decisions of the presidents will be analyzed. As a result of the analysis carried out in the conclusion section, there will be an inference and foresight on American internal policy and foreign policy regarding the isolationist discourse in the Donald Trump period that is on the agenda.