bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepmarc: A 96 week randomised controlled feasibility trial of add-on maraviroc in people with HIV and non-alcoholic fatty liver disease
Authors: Bradshaw Daniel , Abramowicz Iga , Bremner Stephen , Verma Sumita , Gilleece Yvonne , Kirk Sarah , Nelson Mark , Housman Rosalie , Miras Helena , Orkin Chloe , Fox Ashini , Curnock Michael , Jennings Louise , Gompels Mark , Clarke Emily , Robinson Rachel , Lambert Pauline , Chadwick David , Perry Nicky 
Published: July 2023

Objectives
Maraviroc may reduce hepatic inflammation in people with HIV and non-alcoholic fatty liver disease (HIV-NAFLD) through CCR5-receptor antagonism, which warrants further exploration.

Methods
We performed an open-label 96-week randomised-controlled feasibility trial of maraviroc plus optimised background therapy (OBT) versus OBT alone, in a 1:1 ratio, for people with virologically-suppressed HIV-1 and NAFLD without cirrhosis. Dosing followed recommendations for HIV therapy in the Summary of Product Characteristics for maraviroc. The primary outcomes were safety, recruitment and retention rates, adherence and data completeness. Secondary outcomes included the change in Fibroscan-assessed liver stiffness measurements (LSM), controlled attenuation parameter (CAP) and Enhanced Liver Fibrosis (ELF) scores.

Results
Fifty-three participants (53/60, 88% of target) were recruited; 23 received maraviroc plus OBT; 89% were male; 19% had type 2 diabetes mellitus. The median baseline LSM, CAP & ELF scores were 6.2 (IQR 4.6–7.8) kPa, 325 (IQR 279–351) dB/m and 9.1 (IQR 8.6–9.6) respectively. Primary outcomes: all individuals eligible after screening were randomised; there was 92% (SD 6.6%) adherence to maraviroc [target >90%]; 83% (95%CI 70%-92%) participant retention [target >65%]; 5.5% of data were missing [target <20%]. There were noo Serious Adverse Reactions; mild-moderate intensity Adverse Reactions were reported by five participants (5/23, 22% (95%CI 5%-49%)) [target <10%]. All Adverse Reactions resolved. Secondary outcomes: no important differences were seen by treatment group for the change from baseline in LSM, CAP or ELF scores

Conclusions
This feasibility study provides preliminary evidence of maraviroc safety amongst people with HIV-NAFLD, and acceptable recruitment, retention, and adherence rates. These data support a definitive randomised-controlled trial assessing maraviroc impact on hepatic steatosis and fibrosis.

Trial registration
Clinical trial registry: ISCRTN, registration number 31461655.
Zero fruits/vegetables consumption and associated factors among Children aged 6–23 months in Ethiopia: Mixed effect logistic regression analysis
Authors: Semagn Birhan Ewunu , Abubakari Abdulai 
Published: July 2023

Background
The first two years of life is a vital period for promoting optimal growth, development and health. The lifelong nutritional habit and overall health of children is influenced by their early age feeding practice. Ethiopia is among the top five countries in Sub-Saharan Africa with the highest burden of zero fruits/vegetables consumption. This study aims to access factors associated with zero fruits/vegetables consumption among children aged 6–23 months in Ethiopia.

Methods
The study analyzed Ethiopian Mini Demographic and Health Survey 2019 dataset with a total weighted sample of 1459 young children aged between 6–23 months and who were living with their mothers. Data cleaning, coding and labeling were done using STATA version 14 software. Multilevel mixed effect logistic regression model was employed to identify associated factors.

Results
Exactly 69.3% of children aged 6–23 months in Ethiopia had zero fruits/vegetables consumption. In the multivariable multilevel binary logistic regression analysis a child from household with middle (AOR = 0.55, 95% CI: 0.35, 0.86) and rich (AOR = 0.37, 95% CI: 0.23, 0.60) wealth index, mothers who aged between 25–34 years old (AOR = 0.44; 95%CI = 0.29–0.69), mothers who were married/living with partner (AOR = 3.21; 95%CI: 1.58–6.52), children of mothers who follow Islamic religion (AOR = 0.34, 95% CI: 0.19, 0.61), mothers who had more than four ANC visits during their most recent pregnancy (AOR = 0.57; 95%CI: 0.39–0.83), children in age group of 12–18 month(AOR = 0.41, 95% CI: 0.28, 0.59), and 19–23 months (AOR = 0.26, 95% CI: 0.17, 0.40), health facility delivery (AOR = 1.52, 95% CI; 1.00–2.30), and small peripheral regions (AOR = 4.40, 95% CI; 1.39–13.97) were found to be significant factors associated with children’s zero fruits /vegetables consumption. The Interclass correlation coefficient (ICC) value in the null model was 0.34, which indicates that 34% of the variation in children’s zero fruits /vegetables consumption was attributed to the variation between clusters.

Conclusion
This study found that zero fruits/vegetables consumption among children aged 6–23 months in Ethiopia is high. Therefore, efforts should be made by stakeholders who are concerned about optimal diet and health of children to improve fruits/vegetables consumption of children particularly those from poor households, young mothers (15–24), and peripheral regions of Ethiopia. This could be done during ANC follow up visits and during nutrition counseling.
A study on the fractal and permeability characteristics of coal-based porous graphite for filtration and impregnation
Authors: Wang Qili , Wang Jing , Yang Shuwei , Sun Jiarui 
Published: July 2023

Abstract
In order to distinguish the differences in the heterogeneous fractal structure of porous graphite adopted in the filtration and impregnation, the fractal dimensions (FDs) were obtained by the mercury intrusion porosimetry (MIP) to calculate the volumetric FDs of ten graphite samples, following the fractal theory. The FD expression of the tortuosity along with all the parameters from the MIP test was optimized to simplify the calculation. In addition, the percolation evolution process of mercury in the porous media was analyzed based on the data collected in the experiment. According to the analysis conducted, the FDs in the backbone formation regions of samples varied from 2.695 to 2.984, with 2.923 to 2.991 in the percolation regions and 1.224 to 1.544 in the tortuosity. Based on the correlation coefficients

(

R

2

)

({R}^{2})

ranging between 0.906 and 0.999, and the root mean square errors ranging between 0.0001 and 0.0065 mL g−1, a high level of reliability was identified. According to the MIP test, the mercury distribution in porous graphite demonstrated a transitional process from the local aggregation, the gradual expansion, the infinite cluster connection to the global connection.
The mechanisms of inhibition and lubrication of clean fracturing flowback fluids in water-based drilling fluids
Authors: Liu Huaizhu , Chen Dong , Zhao Kangning , Hu Binbin , Zhang Jianjia , Ning Yang , Shan Tong , Zhang Jie , Zhang Wangyuan , Zhang Fan 
Published: July 2023

Abstract
This study presents a novel approach for the reuse of uncontaminated fracturing flowback fluids to improve the inhibitory and lubricating properties of water-based drilling fluids (WBFs), curb environmental pollution arising from flowback fluids, and substantially mitigate the expenses associated with WBFs. The experimental design was optimized using orthogonal experiments and range analyses, whereby the modified rubber powder was set at 2.0%, xanthan gum at 0.15%, and a plant phenol to modified complexing agent ratio of 1:0.01. The assessment of the performance evaluation tests indicated that the use of uncontaminated fracturing flowback fluids as the base water can remarkably enhance the inhibitory and lubricating properties of WBFs. Precisely, this approach reduces the linear expansion rate from 62.31% to 21.25%, the reduction rate of extreme pressure lubrication coefficient by 87.98%, and the reduction rate of mud cake sticking factor by 59.86%. This investigation has established the potential environmental and economic benefits of reusing clean fracturing flowback fluids in WBFs.
circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis
Authors: Tian Rui , Li Huixin , Ren Songjie , Li Shukui , Fang Run , Liu Yang 
Published: July 2023

Abstract
Circular RNA (circRNA) THBS1 has been shown to exist as an oncogene in non-small-cell lung cancer, but its role in cervical cancer is still unclear. Our experiment aimed to uncover the functions and specific mechanism of circRNA THBS1 in cervical cancer cells. Levels of circRNA THBS1 and miR-543 in cervical cancer tissues and cell lines were assessed by RT-qPCR. starBase and dual luciferase reporter gene assay were applied for investigating the correlation between miR-543 and circRNA THBS1/HMGB2. Cell proliferation and apoptosis were evaluated by MTT and flow cytometry, respectively. Furthermore, the levels of HMGB2, E-cadherin, and N-cadherin in HeLa cells were determined by RT-qPCR and western blot analysis. Our data revealed that circRNA THBS1 was significantly upregulated and miR-543 was low expressed in cervical cancer tissues and cell lines. circRNA THBS1 interacted with miR-543 and negatively regulated miR-543 expression in HeLa cells. Silencing of circRNA THBS1 remarkably suppressed HeLa cells’ viability, accelerated cells’ apoptosis, and inhibited the EMT of HeLa cells, while these changes were reversed by miR-543 inhibitor. Moreover, miR-543 affected HeLa cells by targeting HMGB2. In conclusion, circRNA THBS1 silencing inhibited the malignant biological behaviors of cervical cancer cells via the regulation of miR-543/HMGB2 axis.
Monopolistic Screening Under Mental Accounting: Applications to Loan Markets with Collateral
Authors: Kim Byung-Cheol 
Published: July 2023

AbstractThis paper extends the standard model of monopolistic screening to allow for some consumers who engage in narrow framing, a prominent behavioral bias of mental accounting. Narrow framing generates a bias toward high quality-price ratios, which induces even high-type consumers to choose a menu that targets low-type consumers. To strategically account for narrow framing, when the monopolist induces the high-type consumers to stay with the more expensive menu, there arises a downward quality distortion even at the top and a smaller downward distortion at the bottom. Then, we apply this model to optimal loan contracts to screen heterogeneous borrowers with different default risks. We find that the lender optimally reduces the collateral requirement for low-risk borrowers when some high-risk borrowers are subject to narrow framing. This result empirically implies that narrow framing may lead to smaller credit rationing and lower monitoring intensity in the lending markets.
Introduction: towards a diachronic typology of the middle voice
Authors: Inglese Guglielmo , Sansò Andrea 
Published: July 2023

Abstract
Much of the typological research on the middle voice has so far largely focused on the cross-linguistic definition and status of the middle as a voice category and its relationship to other voice operations such as reflexives and passives. Diachronic research on the middle, especially in a cross-linguistic perspective, remains to these days comparatively marginal. Overall, the existing studies have argued that middle markers generally originate from reflexive markers, and that the reflexive > middle diachronic path is unidirectional. This special issue collects a number of papers that address the diachrony of middle markers cross-linguistically, with the goal of either contributing to refine our understanding of already known diachronic pathways leading to middle markers or challenging assumptions on their possible historical sources (which go well beyond reflexives only) and the purported unidirectionality in their development.
From verbalizer to middle marker: the diachrony of middle voice in Malayic
Authors: Karaj David M. , Sansò Andrea 
Published: July 2023

Abstract
In Malayic languages, prefixes derived from Proto-Malayic *(mb)AR- are characterized by an unusual multifunctionality pattern. On the one hand, continuators of *(mb)AR- may encode functions that are typical of middle markers across languages. On the other hand, they are used as denominal verb formatives. The aim of this article is to provide a diachronic explanation for such an unusual combination of functions. The denominal verbalizing function of *(mb)AR- appears to be primary, and a diachronic scenario can be sketched through which a denominal verb formative has extended to cover a portion of the functional space cross-linguistically encoded by middle markers.
Introduction
Authors: Bruno Nicoletta 
Published: July 2023

Abstract
The papers gathered in this Special Issue cover different phases of ancient, medieval, and modern Greek and Latin and explore an array of issues and trends dealing with historical aspects of Greek and Latin lexicography. The articles have been organized into three thematic units following chronological order: (i) ancient Greek and Latin lexicography; (ii) Greco-Latin lexicography in late antiquity, the Middle Ages, and the modern world; and (iii) uses, perspectives, and ongoing projects in Greco-Latin lexicography. Some papers address more formal issues (linguistic, morphological, semantic, and syntactic) relevant to the study of Greek and Latin lexicography, while other contributions deal with ongoing lexicographical projects, offering fresh perspectives on the future of lexicography.
Considerations on Some Notable Words in a Latin Account of Payments from Tebtynis
Authors: Pezzella Alessia 
Published: July 2023

Abstract
This paper examines some notable words of both Latin and Greek origin in a second-century Latin account from Tebtynis (ChLA V 304). In light of new data, it aims to clarify the linguistic status of these words (especially those of Greek origin) and their meaning, updating and extending Adams’ (2003, 445, 519, 628) analysis, and to offer a more detailed view of the use of Latin and its contacts with Greek in second-century Tebtynis.
A Distorted Lemma: Στεφάκης Ἀθηναῖος ἱερομόναχος and a False Biography of Nicholas of Methone
Authors: Benvenuto Carmelo Nicolò 
Published: July 2023

Abstract
This paper aims at reconsidering traditional data available for the figure of the hieromonk Stephen the Athenian, purported to be the author of a biographical compilation about famous monks of Mt Athos and of a biography of the Byzantine theologian Nicholas of Methone, published by the Greek forger Costantinos Simonides at the end of the 19th century. The main source for Stephen the Athenian is provided by a lemma of a biographical encyclopedia written by the Phanariot scholar Demetrius Procopius of Moschoupolis (with the title Succincta eruditorum Graecorum superioris et praesentis saeculi recensio) and published in 1722 by Johann Albert Fabricius at the end of the 11th volume of his Bibliotheca Graeca. The employment of a philological analysis to the extant sources of “Stephen” shows that the figure is indeed to be considered the mere result of the distortion created by Simonides from a lexicographical lemma.
Latin Lexicography and Textual Criticism: A Lexical Note on Valerius Flaccus,

Argonautica

5.380
Authors: Bruno Nicoletta 
Published: July 2023

Abstract
Lexicographical investigation, carried out in the drafting of the verbs renodo and renudo in the Thesaurus Linguae Latinae, can be useful for textual criticism by its proposing of new conjectures or its explanation of existing ones, by reconstructing the history and the use of a given word. This paper discusses Harm Marien Poortvliet’s conjecture renudatam pharetris in place of the transmitted renodatam pharetris in Valerius Flaccus 5.380, which helps us better understand the meaning and the use of the verb renudo in the text and the different value of the prefix re- in renodo and renudo, for which we also consider other contexts such as Hor. epod. 11.28.
Why a Historical and Theological Lexicon of the Septuagint?
Authors: Bellantuono Antonella , Bigoni Laura 
Published: July 2023

Abstract
Since 2010, an international team has been working on the first comprehensive lexicon dedicated to Septuagint Greek, which aims to fill an important gap in the fields of ancient philology and religious studies. The entries include all the relevant word groups used in the translation of the Hebrew Bible, Greek glosses that captured central concepts from classical Hebrew terms and sought to establish suitable expression for certain Realien. This lexicon aims to give a wide perspective on selected lemmas, taking the legacy of classical Greek literature as a starting point and subsequently analyzing the diffusion and usage of the word up through early Christian Literature. This paper will address some of the questions that are being faced by the team and will explore the innovative approach of this lexicographical project through the presentation of samples.
Pluralist Perspectives in the

Thesaurus Linguae Latinae
Authors: Cè Massimo 
Published: July 2023

Abstract
This paper aims to demonstrate that the Thesaurus linguae Latinae, the world’s largest lexicon of ancient Latin and a traditional project rooted in 19th-century philology, makes a significant contribution to today’s intellectual diversity within Classical Studies. By analysing a corpus of 270 lemmas, ranging from r to razīmus, I argue that the TLL’s quietly revolutionary mode of philological pluralism is realized at three levels of lexicographic content: the selection of primary material (choosing textual passages of ancient Latin to be included in the lexicon); the arrangement of individual lexicographic entries (structuring the presentation of primary text in each article); and the annotation of passages, rubrics, and entire articles (providing metalinguistic description, explanation, and commentary). As a whole, my analysis presents the first-ever account of how the TLL systematically reshapes established lexicographic and scholarly practices.
Psychological intervention for gambling disorder: A systematic review and meta-analysis
Authors: Eriksen Jakob W. , Fiskaali Anne , Zachariae Robert , Wellnitz Kaare B. , Oernboel Eva , Stenbro Anna W. , Marcussen Thomas , Petersen Marie W. 
Published: July 2023

AbstractBackground and aimsIncreasingly, gambling features migrate into non-gambling platforms (e.g., online gaming) making gambling exposure and problems more likely. Therefore, exploring how to best treat gambling disorder (GD) remains important. Our aim was to review systematically and quantitatively synthesize the available evidence on psychological intervention for GD.MethodsRecords were identified through searches for randomized controlled trials (RCTs) evaluating psychological intervention for GD via six academic databases without date restrictions until February 3, 2023. Study quality was assessed with the revised Cochrane risk-of-bias tool for randomized trials (RoB2). Primary outcomes were GD symptom severity and remission of GD, summarized as Hedges' g and odds ratios, respectively. The study was preregistered in PROSPERO (#CRD42021284550).ResultsOf 5,541 records, 29 RCTs (3,083 participants analyzed) were included for meta-analysis of the primary outcomes. The efficacy of psychological intervention across modality, format and mode of delivery corresponded to a medium effect on gambling severity (g = −0.71) and a small effect on remission (OR = 0.47). Generally, risk of bias was high, particularly amongst early face-to-face interventions studies.Discussion and conclusionsThe results indicate that psychological intervention is efficacious in treating GD, with face-to-face delivered intervention producing the largest effects and with strongest evidence for cognitive behavioral therapy. Much remains to be known about the long-term effects, and investigating a broader range of treatment modalities and digital interventions is a priority if we are to improve clinical practice for this heterogeneous patient group.
How gambling harms others: The influence of relationship-type and closeness on harm, health, and wellbeing
Authors: Tulloch Catherine , Browne Matthew , Hing Nerilee , Rockloff Matthew , Hilbrecht Margo 
Published: July 2023

AbstractBackground and aimsConcerned significant others (CSOs) can experience gambling-related harm, impacting their health and wellbeing. However, this harm varies depending on the type and closeness of the relationship with the person who gambles. We sought to determine the type and closeness of relationships that are more likely to experience harm from another person's gambling, and examine which aspects of health and wellbeing are related to this harm.MethodsWe examined survey data from 1,131 Australian adults who identified as being close to someone experiencing a gambling problem. The survey included information on relationship closeness, gambling-related harm (GHS-20-AO), and a broad range of health and wellbeing measures; including the Personal Wellbeing Index (PWI), the 12-item Short Form Survey (SF-12), and the Positive and Negative Affect Schedule Short Form (PANAS-SF).ResultsCSOs in relationships where finances and responsibilities are shared were more likely to be harmed by another person's gambling problem, particularly partners (current and ex) and family members. This harm was most strongly associated with high levels of distress and negative emotions, impacting the CSO's ability to function properly at work or perform other responsibilities.Discussion and ConclusionsSupport and treatment services for CSOs should consider addressing the psychological distress and negative emotions commonly experienced by CSOs.