bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative analysis of potential drug-drug interactions in a public and private hospital among chronic kidney disease patients in Khyber Pakhtunkhwa: A retrospective cross-sectional study
Authors: Zafar Roheena , Rehman Inayat Ur , Shah Yasar , Ming Long Chiau , Goh Hui Poh , Goh Khang Wen 
Published: September 2023

IntroductionChronic kidney disease (CKD) is a significant public health challenge due to its rising incidence, mortality, and morbidity. Patients with kidney diseases often suffer from various comorbid conditions, making them susceptible to potential drug-drug interactions (pDDIs) due to polypharmacy and multiple prescribers. Inappropriate prescriptions for CKD patients and their consequences in the form of pDDIs are a major challenge in Pakistan.AimThis study aimed to compare the incidence and associated risk factors of pDDIs among a public and private sector hospital in Khyber Pakhtunkhwa, Pakistan.MethodA retrospective cross-sectional study design was conducted to compare pDDIs among public and private sector hospitals from January 2023 to February 2023. Patients profile data for the full year starting from January 1 2022 to December 302022, was accessed All adult patients aged 18 years and above, of both genders, who currently have or have previously been diagnosed with end-stage renal disease (ESRD) were included. For assessing pDDIs, patient data was retrieved and checked using Lexicomp UpToDate® for severity and documentation of potential drug-drug interactions.ResultsA total of 358 patients’ data was retrieved (with n = 179 in each hospital); however, due to incomplete data, n = 4 patients were excluded from the final analysis. The prevalence of pDDIs was found to be significantly higher in private hospitals (84.7%) than in public hospitals (26.6%), with a p-value <0.001. Patients in the age category of 41–60 years (AOR = 6.2; p = 0.008) and those prescribed a higher number of drugs (AOR = 1.2; p = 0.027) were independently associated with pDDIs in private hospitals, while the higher number of prescribed drugs (AOR = 2.9; p = <0.001) was an independent risk factor for pDDIs in public hospitals. The majority of pDDIs (79.0%) were of moderate severity, and a significant number of patients (15.1%) also experienced major pDDIs, with a p-value <0.001. The majority of pDDIs had fair documentation for reliability rating in both public and private hospitals.ConclusionThe prevalence of pDDIs was higher among CKD patients at private hospitals, and most of the pDDIs were of moderate severity. A considerable number of patients also experienced major pDDIs. The risk of experiencing pDDIs was found to be higher in older patients and among those prescribed a higher number of drugs.
Pemikiran Tasawuf Beudizzaman Said Nursi: Problematika dan Gagasannya
Authors: Pamungkas Limpad Tuhu 
Published: September 2023

Despite its various shortcomings, Sufism is still needed for religious life today in an increasingly secular world. Considering the various attacks launched against Sufism by Islamic puritan and modernist movements, Said Nursi's thoughts can be considered as a middle way to clear up the clouded pre-judgments of Sufism. This study aims to look at the main ideas of Bediuzzaman Said Nursi related to Sufism and the problematic background behind it, as well as to review the challenges faced by Sufism itself. To describe Said Nursi's thoughts on Sufism in this paper, the author will describe objectively Said Nursi's writings that speak explicitly about Sufism, then the author also includes interpretive and analytical elements to reach a broader meaning from those texts. The results of the study found that, for Said Nursi, Sufism is very important for the manifestation of the truth of Islam itself, although it cannot be denied that there are also practices in certain Sufism traditions that are not in accordance with the Sunnah. Therefore, by still referring to the legacy of the Sufism tradition, he offered a new Sufistic path (tariqah) which he named haqiqah, which he considered safer and less risky. Yet, the problem is modernism itself has eroded the esoteric dimension of Sufism itself, while puritanism has textually rejected it. Thus, Said Nursi's thought of Sufism which places a strong emphasis on Shari'a should be brought up.
Keywords: Said Nursi, Sufism, Haqiqah, tariqah, shari’a, sufism problematics
Comparison of the physical properties of different polyimide nanocomposite films containing organoclays varying in alkyl chain lengths
Authors: Lee Seon Ju , Choi Moon Young , Kwac Lee Ku , Kim Hong Gun , Chang Jin-Hae 
Published: September 2023

Abstract
Poly(amic acid) (PAA), a precursor of polyimide (PI), is synthesized by reacting dianhydride 4-(2,5-dioxotetrahydrofuran-3-yl)-1,2,3,4-tetrahydronaphthalene-1,2-dicarboxylic anhydride with diamine 3,3′-dihydroxybenzidine in N,N′-dimethylacetamide. Organoclays with different alkyl chain lengths were dispersed in PAA, and the weight percentages (wt%) of the organoclays varied. The PI hybrid films were prepared over multiple steps under heat treatment conditions. Bentonite (BTN) was used as the pristine clay, and octylamine (C8) and hexadecylamine (C16) were used to chemically modify the surface of BTN to obtain the desired organoclay samples. Organoclays C8-BTN and C16-BTN were dispersed in a PI matrix, and the organoclay content varied in the range of 1–9 wt%. The thermal, morphological, and optical properties of the PI hybrid films were investigated based on the organoclay content. Although the thermal stability of the PI hybrid film improved when a small amount of organoclay was added, it decreased when the nano-filler content exceeded a certain critical content. Specifically, in the hybrid containing C8-BTN, the critical content is 5 wt%, while in the hybrid with C16-BTN, the critical content is 7 wt%. In addition, the morphology of the clay dispersed in the matrix at the critical content showed the best dispersed phase. The physical properties (thermal characteristics, dispersibility, and optical transparency) of the PI hybrid film containing C16-BTN were better than those of the hybrid film containing C8-BTN. However, the thermal expansion of the C8-BTN hybrid was lower than that of the C16-BTN film at the same content.
Distinguishing Fine Structure and Summary Representation of Sound Textures from Neural Activity
Authors: Berto Martina , Ricciardi Emiliano , Pietrini Pietro , Weisz Nathan , Bottari Davide 
Published: September 2023

AbstractThe auditory system relies on both local and summary representations; acoustic local features exceeding system constraints are compacted into a set of summary statistics. Such compression is pivotal for sound-object recognition. Here, we assessed whether computations subtending local and statistical representations of sounds could be distinguished at the neural level. A computational auditory model was employed to extract auditory statistics from natural sound textures (i.e., fire, rain) and to generate synthetic exemplars where local and statistical properties were controlled. Twenty-four human participants were passively exposed to auditory streams while the electroencephalography (EEG) was recorded. Each stream could consist of short, medium, or long sounds to vary the amount of acoustic information. Short and long sounds were expected to engage local or summary statistics representations, respectively. Data revealed a clear dissociation. Compared with summary-based ones, auditory-evoked responses based on local information were selectively greater in magnitude in short sounds. Opposite patterns emerged for longer sounds. Neural oscillations revealed that local features and summary statistics rely on neural activity occurring at different temporal scales, faster (beta) or slower (theta-alpha). These dissociations emerged automatically without explicit engagement in a discrimination task. Overall, this study demonstrates that the auditory system developed distinct coding mechanisms to discriminate changes in the acoustic environment based on fine structure and summary representations.
A Study of Sensing (S) and Intuition (N) Personality Characteristics in Selected Business School Students in Gujarat State
Authors: Makwana Kirti 
Published: September 2023

Personality is one of the utmost important assets of an individual which aids in categorizing the bounds of success, happiness and achievement in our life[1]. The study explores the sensing and intuitive personality dimensions of selected business school students across Gujarat state. Further, the study explores statistical differences in terms of various demographic aspects. NERIS Type Explorer® Scale was used to check the personality type of a total of 1067 management students. 69.5 per cent (742) of the respondents have a Sensing (S) personality dimension compared to 30.5 per cent (325) Intuition (N) personality dimension as dominating type. The conclusions of this research study are also reinforced by past research work which confirms that there are noteworthy differences between Sensing (S) and Intuitive (N) personality dimensions regarding selected demographic variables.
Cuestionario Honey-Alonso de estilos de aprendizaje (CHAEA). Propiedades psicométricas en estudiantes universitarios colombianos
Authors: Villarreal Fernández Jorge Eliécer 
Published: September 2023

Introducción: El objetivo de este artículo resultado de investigación es presentar los resultados del proceso de análisis psicométrico del Cuestionario Honey-Alonso de Estilos de Aprendizaje (CHAEA) en universitarios en Colombia.

Método: La metodología está inserta en los estudios instrumentales, busca identificar las propiedades psicométricas de un instrumento. La muestra fue de 2230 estudiantes en el Análisis Factorial Exploratorio y de 661 para el Análisis Confirmatorio, ambas muestras no aleatorias. Se utilizaron los Modelos de Ecuaciones Estructurales (SEM) para la etapa confirmatoria.

Resultado: El resultado fue un instrumento de 25 ítems, 4 factores, compuestos de reactivos organizados diferente al constructo original, más cercano al modelo de Kolb, propiedades psicométricas aceptables de acuerdo con los planteamientos teóricos utilizados, dirigida a valorar los estilos de aprendizaje confirmados y etiquetados –Investigador, Práctico, Experimentador y Activo– en el ámbito educativo.

Conclusión: El proceso de validación realizado permite que el uso del instrumento sea considerado como válido y confiable para Estudiantes Universitarios del contexto educativo colombiano. De todas maneras, hay que tener en cuenta las condiciones de aplicación y siempre es importante realizar nuevos estudios en diferentes niveles educativos que puedan dar cuenta de información psicométrica más sólida.
Revisión documental sobre la formación y el conocimiento del profesor de matemáticas
Authors: Cruz-Rojas Gilbert Andrés 
Published: September 2023

Este artículo presenta los resultados de una revisión documental de artículos de investigación publicados en el periodo 2015-2019 en el Congress of the European Society for Research in Mathematics Education (CERME), Psychology mathematics education (PME) y North American Chapter of the International Group for the Psychology of Mathematics Education (PME-NA). Esta revisión se realizó con la intención de determinar los problemas de investigaciones, enfoques teóricos y metodológicos que se utilizan en el estudio sobre el conocimiento del profesor de matemáticas que se ocupan de habilidades situadas, y los enfoques que permiten estudiar prácticas con tecnología. Se toma como perspectiva metodológica la investigación documental, la cual, se desarrolla mediante una clasificación de documentos, a través de palabras claves como la Formación Docente, Conocimiento del Profesor de Matemáticas, Competencia Matemática y el Enfoque Documental. Se reconoce a partir del desarrollo metodológico, que existe una discusión al interior de la comunidad de educadores matemáticos, frente a los procesos de formación docente y su incidencia en las prácticas de enseñanza; en especial al sentido, alcances y limitaciones de programas de formación de profesores de matemáticas.
Didática das Ciências Sociais na Formação de Professores no Espaço Luso-Brasileiro
Authors: Hortas Maria Joao , Dias Alfredo 
Published: September 2023

Este número temático dedicado à “Didática das Ciências Sociais no espaço Luso-Brasileiro”, o número 13 da REIDICS, permite alargar o nosso horizonte sobre o estudo e a reflexão que têm vindo a ser produzidos a respeito do lugar e das finalidades da Didática das Ciências Sociais, na formação inicial de professores, no Brasil e em Portugal.
Estes dois territórios, unidos e separados pelo oceano Atlântico, encetaram uma relação colonial no século XVI e constituem-se hoje como um espaço político e diplomático, social e cultural, que partilha preocupações sobre causas comuns. Entre as múltiplas partilhas, encontramos neste número da REIDICS docentes e investigadores de Ciências Sociais e da sua Didática que, dos dois lados do Atlântico, lecionam nos cursos de formação inicial de professores.
Seleção de Fungos Celulolíticos do Intestino Grosso de Borregos e Ovelhas Criados em Pastagens Tropicais
Authors: Martins Júnior Valdo Soares , Duarte Eduardo Robson , Silva Kellerson Luiz da , Freitas Cláudio Eduardo Silva , Pessoa Flávia Oliveira Abrão , Almeida Patrícia Natalícia Mendes de 
Published: September 2023

O ambiente ruminal é composto por inúmeros microrganismos, onde cada um deles possui um papel fundamental no aproveitamento das dietas ingeridas pelos ruminantes, os fungos são seres unicelurares que atuam degradando as porções fibrosas dessa dieta. Objetivou-se neste estudo avaliar a atividade celulolítica (AC) de fungos micelianos aeróbios provenientes do trato digestório de ovinos. Foram identificados e avaliados 38 isolados de fungos micelianos provenientes de borregos e ovelhas, após o reisolamento, amostras desses microrganismos foram inoculadas em meio C, contendo celulose microcristalina a 1% como única fonte de carbono e incubadas em estufa a 37 °C, em triplicata, por um período de três dias. As leituras da AC foram realizadas após 24, 48 e 72 horas de incubação. Foi adicionado solução contendo vermelho congo e após 15 minutos, as placas foram lavadas com 15 mL de solução 1M de NaCl. Os índices de AC foram calculados pela razão entre o halo de degradação de celulose e o halo da colônia. Dois isolados do gênero Aspergillus e um Trichoderma sp. apresentaram índice AC maior que um, apresentando bom crescimento ao utilizarem esse polissacarídeo com única fonte de carbono. Futuros estudos devem avaliar o potencial desses fungos como probióticos na alimentação de ruminantes ou para microbiologia industrial.
Palavras-chave: Ovinos. Celulose. Trato digestório. Norte de Minas Gerais.
Abstract
The ruminal environment is composed of numerous microorganisms, each of which plays a fundamental role in the use of the diets ingested by ruminants, fungi are unicellular beings that act by degrading the fibrous portions of this diet. The objective of this study was to evaluate the cellulolytic activity (CA) of aerobic mycelial fungi from the digestive tract of sheep. Thirty-eight isolates of mycelial fungi from lambs and sheep were identified and evaluated, after re-isolation, samples of these microorganisms were inoculated in medium C, containing 1% microcrystalline cellulose as the only carbon source, and incubated in an oven at 37 °C, in triplicate, for a period of three days. AC readings were performed after 24, 48 and 72 hours of incubation. Solution containing congo red was added and after 15 minutes, the plates were washed with 15 mL of 1M NaCl solution. CA indices were calculated by the ratio between the cellulose degradation halo and the colony halo. Two isolates of the genus Aspergillus and one Trichoderma sp. showed CA index greater than one, showing good growth when using this polysaccharide as a single carbon source. Future studies should assess the potential of these fungi as probiotics in ruminant feed or for industrial microbiology.
Keywords: Sheep. Cellulose. Digestive tract. North of Minas Gerais.
Evaluation of tear function and ocular surface changes in patients with pseudoexfoliation
Authors: Kushwah Swati , Thamodharan Sangeetha , Raju Kalyani 
Published: September 2023

This study intends to evaluate the Tear function and ocular surface changes in patients with pseudoexfoliation.This cross-sectional study will be conducted on a minimum of 45 patients fulfilling the inclusion criteria in the department of Ophthalmology, at tertiary care institute. Tear meniscus height (TMH), Schirmer’s test, tear breakup time (TBUT), fluorescein staining, conjunctival impression cytology were used to assess dry eye disease in pseudoexfoliation (PEX) patients. In our study the majority of patients with PEX were &#62;70 years and females (23) are more than males (22). According to Grading of dry eye, 41(45.5%) were moderate grade, 24(26.7%) were mild grade, 13(14.5%) were severe grade and 12 (13.3%) were normal grade. Conjunctival impression cytology, fluorescein staining, TBUT, Schirmer's tests, and TMH, all showed a statistically significant results with dry eye in the current study. The patients with pseudoexfoliation syndrome are more prone to develop dry eye, as it causes tear film irregularities and a reduction in the number of goblet cells which is evident with conjunctival impression cytology and Tear film tests.
Dentistry and thromboembolic risk: Strategies for effective patient care
Authors: Kale Preeti Prakash , Kshirsagar Jyoti Sanjay , Vasanth Deepa , Pasha Zameer , Puthenkandathil Rahul , Shenoy Shailesh , Shah Ruhi Rajendra 
Published: September 2023

Thromboembolic events represent a significant healthcare concern, encompassing conditions such as deep vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. The management of patients with a history of thromboembolic events in the dental setting requires careful consideration and collaboration between dentists and healthcare providers. This review article delves into the intricate relationship between thromboembolic events and dentistry.We explore the importance of patient assessment, emphasizing the need for a comprehensive evaluation of medical history, risk factors, and medication regimens. Special attention is given to anticoagulant therapy, and the role of International Normalized Ratio (INR) monitoring in maintaining safe levels of anticoagulation during dental procedures. We discuss the critical timing of dental interventions and the use of local hemostatic measures to minimize bleeding risk.By elucidating these key aspects, this review article aims to provide dental professionals with a comprehensive understanding of thromboembolic events in dentistry, fostering safe and effective oral healthcare for this patient population.
AS3-SAE: Automatic Sleep Stages Scoring Using Stacked Autoencoders
Authors: Vaezi Mahtab , Nasri Mehdi 
Published: September 2023

Purpose: Sleep is a subconscious state, and the brain is active during it. Automatic classification of sleep stages can help identify various diseases. In recent years, automatic sleep monitoring using deep learning networks has attracted the attention of researchers.
Materials and Methods: In this paper, a deep learning type neural network called Stacked Autoencoders (SAEs) is used for automatically classifying sleep stages. SAEs are a kind of neural network with encoder and decoder blocks. The function of these networks is similar to the human brain and is capable of automatically processing signals; also SAEs are robust to noise. To prove the efficiency of this network, in addition to examining the effect of various biological signals such as Electrocardiogram (ECG) and Electroencephalogram (EEG) on the performance of sleep stage classification, Sleep Heart Health Study (SHHS) and ISRUC standard databases have been used, which include night recordings of 30 and 10 healthy humans, respectively.
Results: The accuracy of classifying 2 to 6 classes by SHHS database are 0.995, 0.983, 0.9780, 0.9688, 0.961, and on ISRUC database accuracies are 0.996, 0.994, 0.9511, and 0.9431. Moreover, the proposed network can classify wake, deep sleep, and light sleep using the ECG signal (acc = 0.75, kappa = 0.69).
Conclusion: In the review of the results, it is concluded that sleep stages classification based on EEG signal has better results, still acquisition of ECG signal and its acceptable results can be a good alternative to use. In addition to its high ability of the proposed method to detect sleep stages, this network is robust to noise, which is very necessary and important for the clinical processing of sleep signals.
Protective Effect of Vitis gracilis Wall (Vitaceae) Leaf Decoction on Sexual Vitality and Testis of Alloxan-Induced Diabetic Mice
Authors: Santoso Putra , Ilyas Syafruddin , Midoen Yurnadi Hanafi , Yuniarti Alfi 
Published: September 2023

Diabetes mellitus is profoundly associated with various detrimental outcomes including sexual dysfunction and infertility in males. On the other hand, a medicinal plant namely Vitis gracilis Wall (Vitaceae) has been used as a traditional medicine to enhance vitality. This present study aimed to investigate the protective effect of V. gracilis leaf decoction against diabetes-induced sexual dysfunction and testicle histopathology in adult male mice. The experiment was composed of five different groups namely the control (non-diabetic) group, the diabetes group (without any treatments), and the diabetes treated with V. gracilis decoction at the doses of 25, 50, and 100 g/L, respectively. In addition, the phytochemical constituents of leaf decoction were determined by using Ultra performance-liquid chromatography-mass spectroscopy (UPLC-MS). Our data demonstrated that, despite failing to improve blood glucose profile and body weight, V. gracilis leaf decoction sustained intense sexual behaviors including face and genital kissing, genital licking, and mount toward estrous females. Moreover, lower doses of decoction (25 and 50 g/L) attenuated the diabetes-induced reduction of testis weight and precluded malondialdehyde accumulation in the testicle tissue. The decoction at the lower doses also ameliorated histopathological alterations in the testis, particularly the wall thickness of tubulus seminiferous and the number of necrotic cells. V. gracilis decoction also improved hematological values including hemoglobin, red blood cell count and hematocrit level. In addition, UPLC-MS analysis revealed a total of 26 phytochemical compounds with seven predominant substances. In conclusion, leaf decoction of V. gracilis, particularly at lower doses but not at a higher dose, exerted a protective effect on sexual vitality, testicle tissue, and hematological value under diabetic condition. The beneficial effects of V. gracilis decoction might be associated with its various bioactive compounds. Therefore, V. gracilis leaves may be a future candidate as a potent natural drug for male sexual vitality and testicle protection against diabetes.