bluuebunny/crossref_metadata_2025_split huggingface dataset:
Battle royale optimizer with ring neighborhood topology
Authors: Akan Taymaz , Zálabský Tomáš , Shirini Kimiya , Bhuiyan Mohammad A. N 
Published: March 2023

Abstract

Recently, battle royale optimizer (BRO), a game-based metaheuristic search algorithm, has been proposed for use in continuous optimization, inspired by a genre of digital games known as “battle royale.” In BRO, each individual chooses the nearest opponent as a competitor. For this purpose, the Euclidean distance between individuals is calculated. This interaction corresponds to an increase in computational complexity by a factor of \(n\). For the purpose of improving the computational complexity of BRO, a modified methodology is proposed using a ring topology, namely, BRO-RT. In the modified version, a set of individuals is arranged in a ring such that each has a neighborhood comprising a number of individuals to its left and right. Instead of a pairwise comparison with all individuals in the population, the best individual among the left and right neighborhoods is selected as the competitor. The proposed scheme has been compared with the original BRO and six popular optimization algorithms. All algorithms are evaluated by applying them to thirteen unimodal and multimodal benchmark optimization functions from CEC2008 and CEC2010. Experimental results show that the BRO-RT algorithm is competitive with or superior to the other seven methods. In addition, the compression spring design problem was used to estimate the ability of the proposed method to solve real-world engineering problems. These results demonstrate that BRO-RT yields promising results when applied to real-world engineering problems. Finally, while BRO is ranked first, and BRO-RT second, they achieved competitive results; BRO-RT has the advantages of lower computational complexity and faster run times than the original BRO algorithm.
Increase in atmospheric carbonyl sulphide since the last glacial period
Authors: Aydin Murat 
Published: March 2023

Abstract

Carbonyl sulphide (COS) is the most abundant atmospheric sulphur gas with links to terrestrial and oceanic productivity1. A 52,000-year COS record was recovered from a South Pole ice core. We find evidence for COS production in the ice sheet that alters the atmospheric signal in the ice but can be corrected for using sea salt sodium as a proxy. There was substantially less COS in the glacial atmosphere than the Holocene and the deglaciation is marked by a 2-4 fold rise, which is primarily source driven. Oceanic emissions in the form of COS, carbon disulphide (CS2), and dimethylsulphide (DMS) are collectively the largest natural source of atmospheric COS1-7. In the ocean, COS and CS2 are produced primarily by photochemical reactions involving organosulphur compounds3-7, and DMS is a byproduct of phytoplanktonic activity8-12. The large increase in ocean COS emissions during the deglaciation suggests enhancements in emissions of all three sulphur gases and associated climate feedbacks via processes that involve ocean productivity. DMS is a major source of marine sulphate aerosol, inducing negative direct and indirect climate feedbacks8-14. COS is a precursor for background stratospheric sulphate aerosol with impacts on stratospheric chemistry and a net negative radiative impact15-18.
Prognosis in the downer cow syndrome
Authors: Andrews A. H. 
Published: March 2023

The recumbent cow presents many problems to the veterinary surgeon, not least of these is the one of prognosis. Prognosis can never be completely accurate, but it can be determined on average statistics, the signs presented, the continued reassessment of the animal, biochemical enzyme and level changes and the attitude of the stockman.
The recumbent cow around the time of calving can be affected with one of a large number of different conditions.
Economic Analyses of the Seadrift Wind-Aided Wastewater Treatment Plant Operations
Authors: Abena Mbarga Ange Hilaire , Rainwater Ken , Song Lianfa , Cleveland Theodore , Williams William Ross 
Published: March 2023

Seadrift is located on the Texas Gulf Coast with a population of 1,364 people as of the 2010 U.S. Census. In 2012, the city started operation of a $610,878 wind turbine, dedicated to its wastewater treatment plant. The city hoped to save $25,500 yearly using wind energy to displace some of the plant’s electrical demand. The plant’s average load is 0.05 million gallons per day, requiring 236,000 kWh (8.05*108 BTU) yearly. The paper details how Seadrift used manufacturer curves to predict turbine energy production, and how preliminary geotechnical, economic, and environmental analyses help design renewable energy projects. From 2012 to 2015, Seadrift saved $15,928 per year, with yearly wind energy production of 155,738 kWh (5.31*108 BTU) and net present value of $211,493. This study shows how government agencies and rural communities can collaborate to find economically viable solutions to water-energy nexus challenges in Texas and beyond.
Citation: Mbarga AHA, Rainwater K, Song L, Theodore C, Williams WR. 2021. Economic Analyses of the Seadrift Wind-Aided Wastewater Treatment Plant Operations. Texas Water Journal. 12(1):42-57. Available from: https://doi.org/10.21423/twj.v12i1.7096.
Non-Hermitian quantum quenches in holography
Authors: Morales-Tejera Sergio , Landsteiner Karl 
Published: March 2023

The notion of non-Hermitian \mathcal{PT}𝒫𝒯
symmetric quantum theory has recently been generalized to the
gauge/gravity duality. We study the evolution of such non-Hermitian
holographic field theories when the couplings are varied with time with
particular emphasis on the question non-unitary time vs. unitary time
evolution. We show that a non-unitary time evolution in the dual quantum
theory corresponds to a violation of the Null Energy Condition (NEC) in
the bulk of the asymptotically AdS spacetime. We find that upon varying
the non-Hermitian coupling the horizon of a bulk AdS black hole shrinks.
On the other hand varying the Hermitian coupling in the presence of a
constant non-Hermitian coupling still violates the NEC but results in a
growing horizon. We also show that by introducing a non-Hermitian gauge
field the time evolution can be made unitary, e.g. the NEC in the bulk
is obeyed and an exactly equivalent purely Hermitian description can be
given.
Reducing the pollution load of tannery wastewater and the atmospheric emission of hydrogen sulfide using modified tannin
Authors: Uez Débora Eloísa , Hansen Everton , Osório Daniela Migliavacca , de Aquim Patrice Monteiro 
Published: March 2023

Abstract
Industrial wastewater causes several environmental and health issues due to its composition, and hydrogen sulfide is one of the main contaminants from various industrial activities, including tannery wastewater treatment plants. This study aimed to evaluate the application of a modified tannin to remove hydrogen sulfide, chemical oxygen demand, total nitrogen, color, and turbidity from tannery wastewater and to reduce the atmospheric emission of sulfides. The wastewater was treated using modified tannin, aluminum sulfate, and a combination of both. Gaseous sulfide emissions were analyzed qualitatively using paper soaked in lead acetate. The qualitative methodology of hydrogen sulfide in the atmosphere was efficient to identify the most critical areas in the tannery. The wastewater treatment tests showed that the best option was the combination of both coagulants, in a 50:50 ratio, resulting in a total coagulant dosage of 3,000 mg/L. The removal efficiencies achieved were 13.8% sulfides, 23.3% chemical oxygen demand, 9.1% total nitrogen, 97.3% turbidity, and 96.4% color. This treatment technique promotes the replacement of 50% of the aluminum sulfate currently used in the tannery by a non-toxic coagulant and does not require chemicals to adjust the pH of the wastewater.
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical
BH3 Domain of Non-Bcl-2 Family Proteins
Authors: Ku Bonsu 
Published: March 2023

Abstract:
Anti-apoptotic and anti-autophagic Bcl-2 homologues commonly contain a hydrophobic
groove in which the BH3 domain is accommodated. The BH3 domain is usually considered a feature
of Bcl-2 family members; however, it has also been found in various non-Bcl-2 family proteins. Although
interactions among Bcl-2 family members have been extensively investigated and highlighted,
those mediated by the BH3 domain of non-Bcl-2 family proteins have not been the focus of substantial
research. In this review, the author conducted a structural analysis of Bcl-xL complexed with the
BH3 domain of four non-Bcl-2 family proteins, Beclin 1, SOUL, TCTP, and Pxt1, at an atomic level.
Although the overall Bcl-xL-binding modes are similar among these proteins, they are characterized
by limited sequence conservation of the BH3 consensus motif and differences in residues involved in
complex formation. Based on the structural analysis, the author suggests that more “undiscovered”
BH3 domain-containing proteins might exist, which have been unidentified due to their limited sequence
conservation but can bind to Bcl-2 family proteins and control apoptosis, autophagy, or other
biological processes.
Potential Phytochemicals for Prevention of Familial Breast Cancer with
BRCA Mutations
Authors: Shahiwala Aliasgar Fakruddin , Khan Gazala Afreen 
Published: March 2023

Abstract:
Breast cancer has remained a global challenge and the second leading cause of cancer
mortality in women and family history. Hereditary factors are some of the major risk factors associated
with breast cancer. Out of total breast cancer cases, 5-10% account only for familial breast cancer,
and nearly 50% of all hereditary breast cancer are due to BRCA1/BRCA2 germline mutations.
BRCA1/2 mutations play an important role not only in determining the clinical prognosis of breast
cancer but also in the survival curves. Since this risk factor is known, a significant amount of the
healthcare burden can be reduced by taking preventive measures among people with a known history
of familial breast cancer. There is increasing evidence that phytochemicals of nutrients and supplements
help in the prevention and cure of BRCA-related cancers by different mechanisms such
as limiting DNA damage, altering estrogen metabolism, or upregulating expression of the normal
BRCA allele, and ultimately enhancing DNA repair. This manuscript reviews different approaches
used to identify potential phytochemicals to mitigate the risk of familial breast cancer with BRCA
mutations. The findings of this review can be extended for the prevention and cure of any BRCAmutated
cancer after proper experimental and clinical validation of the data.
Physical Exercise to Redynamize Interoception in Substance use Disorders
Authors: Brevers Damien , Billieux Joël , de Timary Philippe , Desmedt Olivier , Maurage Pierre , Perales José Cesar , Suárez-Suárez Samuel , Bechara Antoine 
Published: March 2023

Abstract:
Physical exercise is considered a promising medication-free and cost-effective adjunct
treatment for substance use disorders (SUD). Nevertheless, evidence regarding the effectiveness of
these interventions is currently limited, thereby signaling the need to better understand the mechanisms
underlying their impact on SUD, in order to reframe and optimize them. Here we advance that
physical exercise could be re-conceptualized as an “interoception booster”, namely as a way to help
people with SUD to better decode and interpret bodily-related signals associated with transient states
of homeostatic imbalances that usually trigger consumption. We first discuss how mismatches between
current and desired bodily states influence the formation of reward-seeking states in SUD, in
light of the insular cortex brain networks. Next, we detail effort perception during physical exercise
and discuss how it can be used as a relevant framework for re-dynamizing interoception in SUD. We
conclude by providing perspectives and methodological considerations for applying the proposed approach
to mixed-design neurocognitive research on SUD.
The Anti-psoriatic Effect of Gallic Acid is Associated with the Suppression
of Keratin 6 and Nrf2
Authors: Zhang Jinwei , Qiu Hong , Cao Xiaojing , Han Ling 
Published: March 2023

Background:
Psoriasis is recognized as an autoimmune dermatosis, and keratin 6 (KRT 6) is a
hallmark of psoriasis. Gallic acid (GA) is a natural and small molecule with a series of biological activities.
However, the effect of GA on psoriasis has not been clarified.

Aims:
This study aimed to investigate the anti-psoriatic activity of GA in psoriasis-like mice and in vitro.

Methods:
The transcriptions of the Homo sapiens KRT6 gene, and Mus musculus KRT6 gene, were identified
using a quantitative real-time reverse transcriptase PCR (qRT-PCR) assay. Expressions of KRT 6,
STAT3, pSTAT3, Nrf2, and pNrf2 in HaCaT cells and skin biopsies were determined with a western
blotting assay. The immunofluorescence (IF) assay was used to examine the expression of KRT6,
pSTAT3, and pNrf2 in HaCaT cells. The expression of KRT 6, PCNA, Ki67, and CD3 was evaluated on
the skin of psoriasis-like mice and quantified with histochemical scores (H scores).

Results:
GA significantly inhibited KRT 6 gene transcription and expression in psoriasis-like disease both
in vitro and in vivo. It significantly inhibited the expression of keratinocyte proliferation markers (PCNA
and Ki67), suppressed the expression of CD3 (a marker of T cells), and decreased the thickness of the
folded skin, as well as improved the splenomegaly in imiquimod-induced mice similar to psoriasis. Furthermore,
the suppressing effect of GA on KRT 6 was abolished by the continuous activation of Nrf2
rather than STAT3, although GA significantly inhibited Nrf2 and STAT3 activation in IL-17A-induced
HaCaT cells.

Conclusions:
KRT 6 acts as a potential target for GA against psoriasis, and the anti-psoriatic effect of GA
could be related to Nrf2 signaling.
The e-S.F.E.R.A. Questionnaire: A New Tool For Sport Psychologists Working In Mental Training
Authors: Caputo Andrea , Drivet Stefano , Sandretto Riccardo , Vercelli Giuseppe , Cortese Claudio G. 
Published: March 2023

Background:
Esports are gaining worldwide recognition. Given the characteristics of this discipline, esporters need proper mental preparation. The S.F.E.R.A. model is widely used in sport psychology practice in Italy, aiming to maximize athletes’ performance and improve five mental factors: Synchrony, Strength, Energy, Rhythm, and Activation.

Objectives:
The present study aims at 1) developing a questionnaire to detect those factors and 2) investigating their similarity with more classical psychological dimensions.

Methods:
A sample of 211 players of competitive online games filled out the “e-S.F.E.R.A. Questionnaire”. Confirmatory Factor Analysis for each factor and regressions on Engagement, Flow and Addiction were performed.

Results:
Results 1) confirm the monofactorial structures of mental factors and 2) show the positive relations of Energy with Vigor and Dedication of Engagement and Activation with all dimensions considered, including Addiction.

Conclusion:
This study provides sports psychologists with a new framework and tools for esporters’ mental optimization.
Part One: Stability Analysis of Hydrogen-CNG Powered Vehicle
Authors: Kale Amar , Kadri Usman , Kamble Jayesh , Badgujar Kushal , Kharade Prakash 
Published: March 2023

Background:
When conventional petroleum-based liquid fuels are combusted, several
hazardous pollutants are produced. These pollutants are noxious for both human beings and the
environment.

Objective:
This study aims to analyze the stability of Hydrogen-CNG powered vehicles. Hydrogen
has the potential to be one of the most sustainable fuels of the future, decrease the global
dependence on fossil fuel resources, and lower the pollutant emissions from the transportation
industry. Though we have alternative non-conventional sources of energy, the perfect one to use as
the energy source for vehicles is hydrogen. The mixture of Hydrogen and CNG provides excellent
properties as fuel for transportation. A fast and accurate control system is designed that allows the
combustion of pure Hydrogen.

Methods:
Combination of Hydrogen with CNG can increase the power and efficiency of the
vehicle. The vehicle powered by Hydrogen-CNG needs an electronic control system assuring the
operation of its discrete components. MIMO system models having brakes and acceleration inputs
are considered.

Results:
Results are presented for the vehicle transfer function in the form of Bode plots, Root
locus, and Routh Hurwitz judging the stability of the vehicle.

Conclusion:
The main goals of the paper that is to analyze the stability of the vehicle and design an
efficient control system are achieved. Obtaining the transfer function for governing equations for
understanding the stability of the plant and generating a visual representation showing the relation
between the variable quantities have been achieved in this paper.
Novel Once Weekly Basal Insulin Fc (BIF) Achieved Similar Glycemic Control with A Comparable Safety Profile Versus Insulin Degludec in Patients with Type 1 Diabetes (T1D)
Authors: Kazda Christof M. , Bue-Valleskey Juliana M. , Chien Jenny , Zhang Qianyi , Chigutsa Emmanuel , Landschulz William , Wullenweber Paula , Haupt Axel , Dahl Dominik 
Published: March 2023

<p> </p>
<p><strong>Objective</strong></p>
<p>Basal Insulin Fc (BIF; insulin efsitora alfa; LY3209590), a fusion protein combining a novel single-chain insulin variant with a human IgG Fc domain, is designed for once weekly basal insulin administration. This Phase 2 study assessed safety and efficacy of BIF versus degludec in N=265 patients with type 1 diabetes (T1D) using multiple daily injections.</p>
<p><strong>Research Design and Methods</strong></p>
<p>During this randomized, parallel, open-label study, patients with T1D were randomized (1:1) to receive BIF once weekly or degludec once daily over the 26-week treatment period. Both groups were titrated to fasting glucose 80-100 mg/dL. Primary endpoint was HbA1c change from baseline to Week 26 (non-inferiority margin=0.4%). Secondary endpoints included percent time in range (TIR, 70-180 mg/dL), CGM fasting glucose (FG), and rate of hypoglycemia.</p>
<p><strong>Results</strong></p>
<p>After 26 weeks, BIF demonstrated non-inferior HbA1c change from baseline versus degludec with a statistically significant treatment difference of 0.17% (90% CI=0.01, 0.32; p=0.07) favoring the comparator. Percent TIR was similar for BIF (56.1%) and degludec (58.9%; p=0.112) at Week 26. FG values were significantly higher for BIF (158.8 mg/dL) versus degludec (143.2 mg/dL; p=0.003). Rates of CGM-derived hypoglycemia were not statistically significantly different for BIF and degludec over 24 hours for Level 1 (p=0.960) or Level 2 (p=0.517) during the treatment period. Occurrence of serious adverse events was similar between BIF and degludec.</p>
<p><strong>Conclusions</strong></p>
<p>Once weekly BIF demonstrated non-inferior glycemic control to once daily degludec (treatment difference: 0.17% favoring degludec) and no difference in hypoglycemia or other safety findings in patients with T1D.</p>
Features of sociological analysis of religion in Russia during the Imperial period of its history (Ending)
Authors: Elishev S. O. 
Published: March 2023

The article deals with the features of sociological analysis of religion in Russia during the imperial period of its history. The national sociological tradition of studying religion as a socio-cultural phenomenon and a social institution, which was developed during this period, had its own unique and peculiar appearance and was just begun to revive again in post-Soviet Russia, contrasts with the tradition that took place in the West. In this context, the appeal to unfortunately undeservedly forgotten works of classics of Russian religious and socio-political though is very promising area of modern sociological research.When studying this problem, the author emphasizes the study of the works of representatives of three ideological areas of Russian religious and socio-political thought: conservatism, liberalism and socialism, as well as the peculiarities of the historical development of Russian society and the state and those events that had a significant impact on the formation and development of scientific understanding of religion in Russia. Among such features, the author, in particular, refers to the formation of an “antisystem” (systemic integrity of people who take a dim view of their homeland, hate their own nation, its values and culture, history, traditional religious, political and social systems) among the Russian intelligentsia, bureaucracy and part of the elite of Russian society, under a certain influence of Westernism, as a consequence of the spiritual schism of the 18th century, which occurred in the educated strata and elite of Russian society.The author of the article pays special attention to the analysis of “Christian sociology”. In his opinion, it is a collective name for the peculiar and original Russian sociological tradition of studying religion as a sociocultural phenomenon and social institute. “Christian Sociology” combines the theoretical developments of representatives of the Russian Slavophile, moderately liberal and conservative camps, secular and religious socio-political thought, striving to formulate and reveal the Christian view and approach to the knowledge and understanding of the life of society and social space.
The Effect of Dietary Supplementation with GUAR (Cyamopsis tetragonoloba) Meal Protein on the Quality and Chemical Composition of Pig Carcasses
Authors: Karpiesiuk Krzysztof , Kozera Wojciech , Daszkiewicz Tomasz , Lipiński Krzysztof , Kaliniewicz Joanna , Okorski Adam , Pszczółkowska Agnieszka , Żak Grzegorz , Matusevičius Paulius 
Published: March 2023

Abstract
Recent research efforts have focused on replacing expensive imported genetically modified soybean meal (GM SBM) as a protein source in animal diets with guar meal characterized by similar nutritional characteristics, which could improve meat quality. The aim of this study was to determine the effect of guar meal protein fed to pigs on carcass quality and the content of major nutrients and fatty acids in the longissimus lumborum (LL) muscle. Pigs were divided into four groups. Control group (1) animals were fed diets containing SBM as the main protein source. In diets for experimental groups 2, 3 and 4, SBM protein was replaced with guar meal protein in 25%, 50% and 75%, respectively. It was found that SBM replacement with guar meal protein at 25% affected carcass weight and the lean content, fat content and protein content of the ll muscle. An analysis of linear correlations revealed a strong negative correlation between the concentrations of monounsaturated fatty acids (MUFAs) and saturated fatty acids (SFAs) in the LL muscle of pigs fed diets containing 25% of guar meal protein, which is nutritionally desirable. The results of this study suggest that the dietary inclusion of guar meal protein at up to 25% of SBM protein has no negative effects on the fattening performance of pigs. Meat quality was not affected by diets fortified with guar meal protein.