bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Assessment of the Thermal Performance of Wood Curtain Wall Frames
Authors: Choquet Yannick 
Published: August 2023

<p>The thermal performance of three different wood framed curtain walls was analyzed and compared to the performance of two thermally broken aluminum curtain walls and one fiberglass curtain wall. U- values for the framing members and overall curtain wall, as well as condensation resistance values were obtained as per NFRC 100 through THERM/WINDOW simulation. In addition, area weighted U-value calculations were done to assess the thermal impact that glass supports had on the frame performance. Finally, whole building energy simulation was done to compare the relative performance of the system analyzed based on the building size. On average, wood curtain wall frames were found to have lower U- values than aluminum curtain wall frames and FG curtain wall frames by 59% and 14 % respectively. In addition, curtain wall sections were found to have lower U-values with wood frames than aluminum frames by an average of 14%. On the other hand, the average condensation resistance of the wood curtain walls was found to be 12% lower than aluminum curtain walls and 3% lower than FG curtain walls. The best performing curtain wall for each frame material were also modelled in OpenStudio/EnergyPlus on two different buildings and the wood curtain wall produced a TEDI that was on average 7% lower than the aluminum curtain wall. Moreover, the glass supports used in wood curtain walls were found to have a much lower impact on the U-value of the frame than the setting chairs used in aluminum curtain walls. Average overall curtain wall U-values and TEDI for the wood and FG curtain walls were found to be virtually the same. </p>
Assessing the Methodology of Freeze-Thaw Degradation in Varying Ages of Brick Masonry Through Frost Dilatometry
Authors: Rouse Tristan 
Published: August 2023

<p>The need for improving the energy efficiency of existing buildings is increasing as the threat of climate change also increases. Load bearing masonry buildings are predominant in major cities such as Toronto, Ottawa and Edmonton. The material was popular in the nineteenth century due to the durability and low risk of fire. However, due to the historic significance of many of these buildings, the addition of insulation occurs on the interior of the masonry wall when retrofitting. This increases the risk of freeze-thaw damage because the ability of the wall to dry out is reduced. </p>
<p>Brick samples are subject to repeated freeze-thaw cycles at specific moisture content levels to determine the exact point at which dilation occurs, known as the critical degree of saturation, Scrit. It appears that the existing methodology has conservative minimum freezing temperatures, to ensure that the majority of pores freeze. However, it is unclear if freezing to low temperatures (-15°C) is necessary to produce viable results. </p>
<p>Both modern and heritage brick samples were used to compare the results of freeze/thaw cycles using different test variables. As previous literature has stated that significant damage occurs between -4°C and -10°C, prompting three tests with minimum freezing temperatures of - 2°C, -6°C and -15°C. An additional three freezing rates were tested, including: -5°C hr, -12°C /hr and -21 °C /hr to understand whether the freezing rate could impact the resulting Scrit in both modern and heritage bricks. It appears that the minimum freezing temperature of -15°C is the preferred freezing temperature to use, as it allows for the majority of water inside the bricks to freeze, causing damage throughout the freeze/thaw cycles. However, it is unclear whether the freezing rate has any impact on the Scrit results, as the results obtained from the freeze/thaw cycles are unreliable. </p>
Predicting Urban Functional Zones with Twitter Data Using the Space-Time Scan Statistics Method and the Random Forest Classifier
Authors: Mawuenyegah Aleta 
Published: August 2023

<p>Studies relating to spatiotemporal data clustering in geosocial media data have laid the groundwork for the analysis of clusters over a large study area. This thesis aims to identify whether urban functional zones can be predicted based on a pattern of data clusters that occurs within each functional zone. A framework is presented for the segmentation, annotation, classification, and validation of the functional zones of land segments in an urban study area. The Space-Time Scan Statistics approach was adopted and used to cluster a dataset of tweets into ‘events’. Characteristic attributes of the detected cluster areas were converted into land segment attributes and used as the input in the Random Forest classifier. Labels for each segment were determined based on high-level land use classes. The classifier was trained, validated, and tested on subsets of the study area. The resulting precision, recall, and F1 score were 88.96%, 89.15%, and 88.23%, respectively. </p>
Development of a Test Method to Evaluate Durability of Concrete Control Joints Against De-Icer Salts
Authors: Elbakari Ramy 
Published: August 2023

<p>This thesis introduces a test method that can be used to evaluate the integrity of control joints. Different salt concentrations and exposure conditions are tested including freeze-thaw cycles, wet-dry cycles and a combination thereof. The test sample is composed of a square block measuring 200x200x120 mm and a joint running in the middle at 40 mm depth. It was revealed that, for accelerated damage to be induced, the test method needs to include two salts with two conditions. The first exposure uses NaCl at 10% concentration with 50 cycles of freeze/thaw- wet/dry alternating every 5 consecutive cycles. The second exposure uses CaCl2 at 15% concentration with 50 cycles of wetting and drying at 5°C. Damage assessment is carried out using two approaches: 1) strength loss under flexural loading and 2) visual damage. The proposed method needs more optimization but is a step in the direction of testing different configuration of joints and concrete properties. </p>
Alantolactone: A Potential Multitarget Drug candidate for Prevention of SARS-CoV-2 Cell Entry
Authors: Zafar Erum , Ahsan Zainab , Maqbool Muhammad Faisal , Zaman Aqsa , Gul Sameena , Maryam Amara , Khan Muhammad , Shakir Hafiz Abdullah , Irfan Muhammad 
Published: August 2023

The novel strain of coronavirus, SARS-CoV-2, has spread adverse effects on human health with high mortality rates worldwide. SARS-CoV-2 is a severe respiratory disease expressed through positive single stranded RNA enveloped virus. SARS-CoV-2 had affected globally and is influencing the economy as well. The rapidly spreading coronavirus infection has discombobulated the researchers in perpetuate search for different or effective therapeutic drugs. Most of the connatural products are proposed to have significant clinical outcomes but their pathways of action are not clear. This molecular docking study presents alantolactone, a bio-active member of sesquiterpene family as a successful inhibitor of SARS-Cov-2 and human receptor proteins. Alantolactone shows high binding affinity with the SARS-CoV-2 target proteins such as spike glycoprotein (S-protein), nucleocapsid protein (N-protein), main protease (MPro), and papain-like protease (PLPro) with a binding affinity of -7.3 kcal/mol, -7.9 kcal/mol, -6.8 kcal/mol, and -7.1 kcal/mol, respectively as well as human receptor proteins associated with the recognition, binding and biogenesis of SARS-CoV-2 such as angiotensin-converting enzyme 2 (ACE-2), receptor binding domain (S1-RBD) and ACE2 interphase, furin, adaptor-associated protein kinase 1 (AAK1), cyclin G-associated kinase (GAK), and both closed and open configurations of the two-pore channel (TPC2) with binding energies of -6.7 kcal/mol, - 6.9 kcal/mol, -8.1 kcal/mol, -7.3 kcal/mol, and -7.9 kcal/mol, respectively. Molecular docking and ADMET properties and toxicity predictions suggest that alantolactone could effectively binds with various viral target protein and human target proteins and could be developed into a novel SARS-coV-2 inhibitor.
GÜRCİSTAN’IN GURİA BÖLGESİ’NDE, AHŞAP ÇANDI CAMİ ÖRNEĞİ: ZOTİ CAMİİ (ზოტის მეჩეთი)
Authors: KAYA Mustafa 
Published: August 2023

Ahşap camiler, İslam’ın erken dönemlerinden beri inşa edilmektedir. Nitekim İslam mimarisinin ilk mabedi Mescid-i Nebevi (Miladi 654) hurma ağacından ahşap direkli olarak inşa edilmişti. Orta Asya’da, Türklerin İslam dinini benimsemesi ile ahşap camiler inşa ettiği bilinmektedir. Bu gelenek, Karahanlılar (9.-13.yy) ile başlayıp, Gazneliler (10-12.yy) ve Selçuklular (11. yy) döneminde anıtsal ve zengin örneklerini vermiştir. Anadolu’ya Selçuklu döneminde taşındığı bilinen ahşap camiler, Beylikler ve Osmanlı döneminde kendine has bir yorum ve kimlik kazanmıştır.
Bu makale, Gürcistan’ın Guria Bölgesi kırsalında arazi çalışmamız ile tespit edilen Zoti Camii’ni içermektedir. Cami, kitabesine göre 1907 yılında Çarlık Rusyası Dönemi’nde ve Osmanlı mimari geleneğinde inşa edilmiştir. Yapı, özgün dokusunu koruyarak ulaşmıştır. Ahşap çandı camiler grubunda incelenen Zoti Camii, plan, mimari ve süsleme özellikleri ile yakın çevrede Acara ve Türkiye’nin Doğu Karadeniz Bölgesi camileri ile benzerlikleri tespit edilmiştir. Camideki süslemelerin, üslup ve teknik yönden Ahıska, Karadeniz ve kısmen de olsa Doğu Anadolu camileri ile benzer olduğu izlenmektedir.
Çalışmanın amacı, daha öncesinde Sanat Tarihi araştırmalarına konu olmayan Zoti Camii’nin, Türk-İslam sanatındaki yeri ve önemini belirleyerek, çandı camilerin Karadeniz Bölgesi’ndeki üslubunu takip edebilmektedir. Bu çalışmada cami; plan, mimari ve süsleme özellikleri Sanat Tarihi disiplini çerçevesinde detaylı olarak tanıtılmış, görseller ve çizimler ile desteklenmiştir. Makalede, Zoti Camii örneği ışığında yapının çağdaş ve yakın çevredeki cami örnekleri ile etkileşim ve farklılıkları belirlenmeye çalışılmıştır.
XVII. YÜZYILDA SAFEVİLER’DE BİR ASKER VE SİYASET ADAMI; SELMAN HAN-I SUBAŞI-YI DUNBULÎ (SELMAN HALİFE)
Authors: PEKOL Fatih 
Published: August 2023

SSelman Han-ı Subaşı-yı Dunbulî veya diğer adıyla Selman Halife-yi Dunbulî, XIII. yüzyıldan XIX. yüzyılın ortalarına kadar tarihin farklı dilimlerinde; Eyyubiler, Akkoyunlular, Osmanlılar, Safeviler, Afşarlar, Zendler, Kaçarlar ve Ruslar adına birçok bölgeyi yönetmiş olan Dunbulî aşiretinin XVII. yüzyıldaki önemli isimlerinden biridir. Safevilerde askerî ve siyasi birçok göreve getirilmiş olan Selman Han-ı Dunbulî, Safevi ordusu ile beraber birçok sefere de iştirak etmiştir. Safevilere olan bağlılığından ötürü Selman Han’a Kurçibaşı ve Rekabdarbaşı gibi askeri ve mülki ünvanlar verilip, Çors ve Selmas hâkimliğine getirilmiştir. Selman Han’ın yönetimi altında bulunmuş bölgeler, Osmanlı-İran sınırında yeralan bölgelerdir. Dolayısıyla gerek adı geçen Han gerekse yönetim altındaki bölgeleri birçok kez Osmanlı Devleti ile İran arasında yaşanan gerilimlerin nedeni olmuş, Safeviler ile Osmanlılar arasında cereyan etmiş pek çok gelişmede öne çıkmışlardır. Örneğin Selman Han-ı Dunbulî Muhammed Paşa yönetimi altında bulanan Erciş ve Adilcevaz gibi Osmanlı topraklarına baskınlar düzenleyip söz konusu bölgeleri yağmalamıştır. Adı geçen Muhammed Paşa’yı esir alıp Safevi sarayına götürmüş ve neticede İran Şah’ının övgüsüne mazhar olmuştur. Osmanlılara karşı verdiği çetin mücadelerden dolayı Şah I. Abbas tarafından “Han” ünvanıyla taltif edilmiştir.
Selman Han-ı Dunbulî ile ilgili özellikle İskender Bey-i Türkmen tarafından kaleme alınan Alem Ara-yı Abbasi isimli eser ile Muhammed İştihardi’nin kaleme aldığı Tezkiretü’l Denabile isimli eserde birçok bilgi mevcuttur. Bu çalışmada mezkur malumatlardan yola çıkarak adı geçen Han’ın askeri ve siyasi kişiliğine değinilmiş olup bu minvalde dönem kaynakları ve sonrasında yazılan eserler karşılaştırılmıştır.
Dampak Perubahan Penggunaan Lahan Pertanian Terhadap Komoditi Unggulan Akibat Pembentukan Kabupaten Buton Selatan
Authors: Hazriani Hazriani , Ido Irfan , Harimuddin Jamal , Restele La Ode , Indriasary Anita 
Published: August 2023

Rapid development has an impact on increasing land use change. The establishment of South Buton Regency in 2014 triggered an increase in development in Batauga District which resulted in the expansion of built-up land and changes agricultural land use. Changes in agricultural land use will affect agricultural productivity, especially leading commodities. This study aims to: (1) determine changes in agricultural land use in Batauga District due to the establishment of South Buton Regency; (2) know the impact of changes in agricultural land use on leading commodities. This study uses quantitative descriptive analysis methods and OBIA. The results of this study include: (1) Changes in agricultural land use due to the formation of South Buton Regency have changed from 3,119.26 acre previously to 2,971.64 acre in 2021; (2) Impact of changes in the use of agricultural land on superior commodities, namely commodities before formation become a base then become non-base after the formation of South Buton Regency and vice versa.. Keywords: Land Use Change, Agriculture, Leading Commodity
Mitigasi Banjir di Kelurahan Wawombalata Kota Kendari
Authors: Widayati Weka , Sawaludin Sawaludin , Indriasary Anita , Aulia Weko Indira Romanti , Rahim Saban 
Published: August 2023

The problem of flooding is still a problem that occurs in urban communities. High water intensity during the rainy season results in the potential for flooding in residential areas around the river flow. This study aims to determine flood mitigation in the Wawombalata sub-district, Kendari City. The method used in this research is survey and map overlay. The results showed that: On the flood hazard map, the area that has the highest hazard class is in the RT 5 section. Meanwhile, the flood hazard in the high class covers parts of the RT 1, RT 2, RT 3, RT 4, RT 5, RT 6 and RT 7. Overall the potential for flooding in the Wawombalata sub-district is classified as a high hazard class up to the highest class around residential areas and community housing. Flood mitigation strategies that can be carried out include: Conducting learning about disaster mitigation and outreach as well as disaster emergency simulations, maintaining the functions of vital objects/public facilities. Coordinating disaster management at the District/City level and and the Central Government. Keywords: Mitigation, Hazard, Flood, Community
KEBIJAKAN PUBLIK DALAM PUSARAN PARTAI POLITIK
Authors: Ridwan Ridwan 
Published: August 2023

Kebijakan dipandang sebagai proses interaksi antara tujuan yang telah ditetapkan dan tindakan-tindakan yang dilakukan untuk mewujudkan tujuan. Kebijakan publik menjadi kewenangan yang dibuat oleh kekuasaan yang sah dalam sebuah sistem pemerintahan, keputusan akhir yang telah ditetapkan secara politik memiliki sifat yang mengikat bagi para pelayan publik untuk melakukan tindakan kedepannya. Partai politik menjadi penentu kebijakan seperti yang tertera dengan Undang-Undang nomor 2 Tahun 2008 tentang partai politik Pasal 11 ayat 1 poin c dimana partai politik berfungsi sebagai sarana penyerapan, penghimpunan dan penyalur aspirasi politik masyarakat dalam merumuskan dan menetapkan kebijakan. Peran partai politik sangat besar dalam menentukan arah kemajuan negara dan bangsa. Kebijakan yang diambil merupakan kepanjangan tangan dari partai politik maka sudah semestinya kepentingan partai politik mendukung dan mengusung pengambil kebijakan harus sesuai dengan kepentingan rakyat. Penulisan ini menggunakan metode analisis kualitatif deskriptif. Dalam metode analisis kualitatif deskriptif, pengumpulan dan analisis dilakukan melalui studi kepustakaan dan mengumpulkan data sekunder melalui referensi yang ada. Hasil studi menunjukan, rakyat sebagai subjek dari sistem demokrasi di Indonesia, mempunyai hak untuk ikut serta dalam menentukan kebijakan melalui kebijakan perwakilan guna dijalankan oleh lembaga eksekutif dan legislatif untuk kesejahteraan rakyat. Partai politik harus merevisi peraturan perundang tentang partai politik dan AD/ART partai agar aspirasi masyarakat menjadi agenda utama dalam pembuatan kebijakan publik.
Exploring the latest understanding on the role of immune mediators, genetic and environmental factors in pathogenesis of allergic rhinitis: a systematic review
Authors: Albloushi Shaimaa , Al-Ahmad Mona 
Published: August 2023

IntroductionDespite well-defined clinical phenotypes of chronic rhinitis, the underlying in-depth pathophysiological mechanism, particularly with reference to the involvement of immune mediators, genetic, and environmental factors, are still not fully understood. Therefore, our aim was to give updated information on the pathogenesis of allergic rhinitis (AR), with an emphasis on the role of cytokines in adults aged 18 years and above. Additionally, we investigated the impact of genetic and environmental factors in the pathogenesis of AR.ResultsA search in various databases identified 1,178 records, and 18 studies were ultimately selected from January 2018 to April 2023. The total sample size in our studies was 4,317, with 2,186 in the experimental and 2,131 in control groups, respectively. The mean age was 33.4 years, with 43% were male, while 57% were female. According to the selected studies, various factors, including immune mediators, particularly cytokines, genetic, and environmental factors, were identified in the development of AR.ConclusionThe selected studies presented findings on different factors and sub-factors in the pathogenesis of AR, making it a challenge for us to compare their results. However, based on our findings, researchers can link our identified factors to potential therapies for AR.
Development and preliminary assessment of a CRISPR–Cas12a-based multiplex detection of Mycobacterium tuberculosis complex
Authors: Xiao Jing , Li Jieqiong , Quan Shuting , Wang Yacui , Jiang Guanglu , Wang Yi , Huang Hairong , Jiao Weiwei , Shen Adong 
Published: August 2023

Since the onset of the COVID-19 pandemic in 2020, global efforts towards tuberculosis (TB) control have encountered unprecedented challenges. There is an urgent demand for efficient and cost-effective diagnostic technologies for TB. Recent advancements in CRISPR–Cas technologies have improved our capacity to detect pathogens. The present study established a CRISPR–Cas12a-based multiplex detection (designated as MCMD) that simultaneously targets two conserved insertion sequences (IS6110 and IS1081) to detect Mycobacterium tuberculosis complex (MTBC). The MCMD integrated a graphene oxide-assisted multiplex recombinase polymerase amplification (RPA) assay with a Cas12a-based trans-cleavage assay identified with fluorescent or lateral flow biosensor (LFB). The process can be performed at a constant temperature of around 37°C and completed within 1 h. The limit of detection (LoD) was 4 copies μL−1, and no cross-reaction was observed with non-MTBC bacteria strains. This MCMD showed 74.8% sensitivity and 100% specificity in clinical samples from 107 patients with pulmonary TB and 40 non-TB patients compared to Xpert MTB/RIF assay (63.6%, 100%). In this study, we have developed a straightforward, rapid, highly sensitive, specific, and cost-effective assay for the multiplex detection of MTBC. Our assay showed superior diagnostic performance when compared to the widely used Xpert assay. The novel approach employed in this study makes a substantial contribution to the detection of strains with low or no copies of IS6110 and facilitates point-of-care (POC) testing for MTBC in resource-limited countries.
Assessing validity of the Klenico diagnostic software system in a large psychotherapeutic inpatient sample
Authors: Reutimann Stefan , Hübscher Noah , Steiner Jasmin , Voderholzer Ulrich , Augsburger Mareike 
Published: August 2023

IntroductionMental disorders are often underdiagnosed in routine diagnostic procedures due to the use of unstandardized assessments; this can result in people either not receiving necessary treatment or receiving ineffective treatment for their condition. Klenico is an online diagnostic software system that facilitates diagnosis of mental disorders in adults through the use of standardized procedures. The procedure encompasses two modules, self-report and clinical validation. The current study aimed to confirm the validity of the Klenico assessment in a large clinical sample.MethodsFully anonymized data from 495 adult inpatients were used. ICD-10 diagnoses were made during an initial interview by the clinical staff. Afterwards, patients filled out self-report questionnaires (BDI-II, BSI, EDE-Q, OCI-R, PHQ-D, and Y-BOCS) and completed the Klenico self-report module, which involves selecting and rating the severity of applicable symptoms. Finally, in the clinical validation module, mental health professionals validated the symptoms endorsed in the self-report module. Six Klenico domains were tested against patient self-reports and routine ICD-10 diagnoses by following the multitrait-multimethod approach. Internal consistency was assessed by calculating Cronbach's alpha.ResultsThe Klenico depressive disorders, OCD, and somatoform disorders domains revealed high correlations with the congruent questionnaires (i.e., those pertaining to these specific disorders) and revealed low correlations with the noncongruent questionnaires (i.e., those pertaining to other disorders), therefore evidencing construct validity. For the eating disorders and psychotic disorders domains, divergent validity was demonstrated. For the anxiety disorders domain, although analysis mostly indicated construct validity, this should be further confirmed.DiscussionOverall, the results largely confirmed the construct validity of the Klenico assessment, demonstrating its use as an easy-to-use, valid, standardized, and comprehensive instrument for diagnosing mental disorders.
Marine invertebrates as proxies for early kelp use along the western coast of South America
Authors: Alcalde Verónica , Flores Carola , Guardia Javiera , Olguín Laura , Broitman Bernardo R. 
Published: August 2023

Coastal societies have lived at the seaward edge of the Atacama Desert since at least 12,000 years ago. Kelp forest ecosystems provide evidence for important subsistence activity along the entire Chilean coast through fishing and gathering. Despite their importance, especially in hyperarid contexts with limited plant abundance, there is scarce evidence of kelp in archaeological contexts, hampering the study of kelp use in the past. In the present study, we use the presence of small marine invertebrates, inhabitants of stipes and holdfasts of macroalgae, as proxies that indicate past kelp presence. We analyze samples of three species of snails (Tegula atra,Tegula tridentata,andDiloma nigerrima) and one limpet (Scurria scurra) from nine archaeological sites dated between 7,000 and 500 cal years before present located around the area of Taltal (25°Lat S). Modern samples of these species were collected to reconstruct the size of fragmented archaeological shells and subsequently estimate the size of harvested kelps. Through this approach, we estimated the size and relative abundance of kelp used by coastal groups that inhabited the southern part of the Atacama Desert for around 6,500 years. Our results are a contribution to the scarce information on the presence and use of kelp in the prehistory of the Americas and contribute to comparative perspectives with other areas of the world where the use of kelp by humans in the past has already been explored.