bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presence of Phthalate Esters Used as Common Plasticisers in Maltese Shoreline Sand
Authors: Muscat Marija , Sinagra Emmanuel , Lia Frederick 
Published: May 2023

DBP and DEHP are two of the most common plasticisers used in modern industries, which have aroused a major concern over their ubiquitous occurrence and hazardous environmental effects. This study presents the first data of phthalates’ occurrence and distribution in the Maltese shoreline sand. DBP and DEHP occurrences’ was investigated in three busy and secluded beaches, respectively. Analytical determination involved quantifying DBP and DEHP from 75 samples using UPLC-MS/MS through triple repeatability. The concentrations ranged between 0.0095–0.07034 µg/g and &amp;lt;LOQ–0.0977 µg/g for DBP and DEHP, respectively. Statistical analysis of the comparison of phthalates in different beaches demonstrated that the occurrence of DBP and DEHP in Maltese shoreline sand varies. The differences in the occurrence of phthalates were attributed to the beaches’ topography and anthropogenic pressures. Analysis of the effects of anthropogenic activities on the occurrence of phthalates showed a positive association. Distribution analysis showed that DBP and DEHP exhibit an uneven distribution along the shoreline. Conversely, different distributions were observed at distances away from the sea. The uneven distributions observed were associated with anthropogenic activities, different chemodynamic properties and wave action. Cluster analysis was performed to prove the interactions between the phthalates’ concentrations and the characteristics of the beaches.
Absence of Weak Localization Effects in Strontium Ferromolybdate
Authors: Suchaneck Gunnar , Artiukh Evgenii 
Published: May 2023

Sr2FeMoO6-δ (SFMO) double perovskite is a promising candidate for room-temperature spintronic applications since it possesses a half-metallic character (with theoretically 100% spin polarization), a high Curie temperature of about 415 K, and a low-field magnetoresistance (LFMR). However, due to different synthesis conditions of ceramics as well as thin films, different mechanisms of electrical conductivity and magnetoresistance prevail. In this work, we consider the weak localization effect in SFMO occurring in disordered metallic or semiconducting systems at very low temperatures due to quantum interference of back-scattered electrons. We calculate the quantum corrections to conductivity and the contribution of electron scattering to the resistivity of SFMO. We attribute the temperature dependence of SFMO ceramics resistivity in the absence of a magnetic field to the fluctuation induced tunneling model. Also, we attribute the decreasing resistivity in the temperature range from 409 K up to 590 K to adiabatic small polaron hopping and not to localization effects. Both fluctuation induced tunneling and adiabatic small polaron hopping do not favor quantum interference. Additionally, we demonstrate that the resistivity upturn behavior of SFMO cannot be explained by weak localization. Consequently, to the best of our knowledge, there is still no convincing evidence for the presence of weak localization in SFMO.
Analysis of Network Pharmacological Efficacy and Therapeutic Effectiveness in Animal Models for Functional Dyspepsia of Foeniculi Fructus
Authors: Choi Na Ri , Jung Daehwa , Kim Sang Chan , Park Jae-Woo , Kim Byung Joo , Choi Woo-Gyun 
Published: May 2023

For centuries, Foeniculi fructus (F. fructus) has been used as a traditional herbal medicine in China and Europe and is widely used as a natural therapy for digestive disorders, including indigestion, flatulence, and bloating. The mechanism by which F. fructus alleviates functional dyspepsia was analyzed through network pharmacology, and its therapeutic effect on an animal model of functional dyspepsia was investigated. The compounds, targets, and related diseases of F. fructus were studied utilizing the traditional Chinese medicine systems pharmacology (TCMSP) database. Information on the target genes was classified using the UniProt database. A network was built using Cytoscape 3.9.1, and functional dyspepsia-related genes were checked using the Cytoscape string application. The efficacy of F. fructus on functional dyspepsia, including gastroparesis and gastrointestinal motility, was confirmed by treatment with its extract in a mouse model of loperamide-induced functional dyspepsia. Seven compounds targeted twelve functional dyspepsia-associated genes. In a functional dyspepsia mouse model, F. fructus significantly suppressed the symptoms when compared to that in the control group. Our animal studies showed that the mechanism of action of F. fructus is closely related to gastrointestinal motility. Based on animal experimental results, the results showed that F. fructus provides a potential means to treat functional dyspepsia, suggesting that its medical mechanism for functional dyspepsia can be described by the relationship between seven key compounds of F. fructus, including oleic acid and β-sitosterol, and 12 functional dyspepsia-related genes.
Whole Yeast Vaccine Displaying ZIKV B and T Cell Epitopes Induces Humoral and Cellular Immune Responses in Murine Model
Authors: Silva Anna Jéssica Duarte , Jesus André Luiz Santos de , Leal Lígia Rosa Sales , Macêdo Larissa Silva , Barros Bárbara Rafaela da Silva , De Sousa Georon Ferreira , Alves Simone da Paz Leôncio , Pena Lindomar José , De Melo Cristiane Moutinho Lagos , Freitas Antonio Carlos de 
Published: May 2023

Improving antigen presentation is crucial for the success of immunization strategies. Yeasts are classically used as biofactories to produce recombinant proteins and are efficient vehicles for the delivery of vaccine antigens, besides present adjuvants properties. Despite the absence of epidemic outbreaks, several vaccine approaches continue to be developed for Zika virus infection. These prophylactic strategies are fundamental given the severity of clinical manifestations, mainly due to viral neurotropism. The present study aimed to evaluate in vivo the immune response induced by P. pastoris recombinant strains displaying epitopes of the Envelope (ENV) and NS1 ZIKV proteins. Intramuscular immunization with heat-attenuated yeast enhanced the secretion of IL-6, TNF-α, and IFN-γ, besides activation of CD4+ and CD8+ T cells, in BALB/c mice. P. pastoris displaying ENV epitopes induced a more robust immune response, increasing immunoglobulin production, especially IgG isotypes. Both proposed vaccines showed the potential to induce immune responses without adverse effects, confirming the safety of administering P. pastoris as a vaccine vehicle. Here we demonstrated, for the first time, the evaluation of a vaccine against ZIKV based on a multiepitope construct, using yeast as a vehicle, reinforcing the applicability of P. pastoris as a whole yeast cell vaccine.
Evaluation of quality-of-life following treatment with Hymovis in patients with knee osteoarthritis and/or meniscal tear
Authors: Balius Ramon , Guillermo Álvarez Rey , Fernando Baró Pazos , Miguel Domínguez Melendez , Enrique Gastaldi Orquín , Alberto Gómez Martin , Luisa Ibáñez Martín , Francisco Lara Pulido , Antonio Leal Graciani , Antonio León Garrigosa , Luis Martín Leis José , Manuel Morales Santias , Luis Pérez Carro , Orlando Pompei Fernandez , Jordi Puigdellívol Grifell , César Quesada de la Gala , Antonio Rodas Pereira José , Andrés Valentí Azcarate 
Published: May 2023

Abstract
Background: Knee osteoarthritis (KOA) and meniscal tears (MT) are the two most common types of knee injuries having an important impact on the quality of life of patients (QoL). The objective is to evaluate the impact on the QoL, physical activity and satisfaction degree of patients with KOA, MT or both conditions after intraarticular Hymovis infiltration.
Methods: Non-interventional, prospective, multicenter study of 165 patients with KOA and/or a MT treated with two injections of Hymovis.
Results: Patients in all three groups (KOA, MT and mixed) reported a high percentage of global QoL improvement (>80 %). KOOS and WOMAC change from baseline improved (p<0.001) for all patients. Physical, sports and recreational activities and Satisfaction with the treatment increased after treatment. (p<0.001). Pain also improved in the three groups (p<0.05).
Conclusion: Intra-articular injections of Hymovis improves QoL, physical function and clinical condition of patients suffering KOA, MT or both conditions.
Subjective wellbeing in developing countries: The case of rural Ethiopia Preprint
Authors: Tekleselassie Tsegay Gebrekidan 
Published: May 2023

Abstract
The study examines the factors that contribute to subjective wellbeing in rural Ethiopia, with a specific focus on the impact of religious, social, and political institutions. Estimations based on heteroscedastic ordered probit models demonstrate that general trust and trust in local political officials are crucial predictors of satisfaction and happiness. This highlights the significance of trust in areas where formal institutions are limited. Participation in both formal and informal institutions is also related to wellbeing, emphasizing the value of participatory democratic institutions in rural areas. In line with findings from other studies, income has a positive effect on both general life satisfaction and happiness, but its influence diminishes after a certain point. Additionally, the findings suggest that broader socio-economic factors, such as religiosity and political governance, strongly predict life satisfaction, while momentary happiness is primarily driven by welfare metrics. The study concludes that future research on subjective wellbeing should distinguish between general satisfaction and momentary happiness, as this could offer valuable insights into the underlying factors contributing to human wellbeing.
Morocco's Coal to Clean Journey: Optimised Pathways for Decarbonisation and Energy Security
Authors: Harland Natasha , Jansen Malte , Yeganyan Rudolf , Tan Naomi , Cannone Carla , Howells Mark 
Published: May 2023

Abstract
Morocco depends on imported fossil fuels for 90% of its primary energy supply. This makes the country vulnerable to unstable fuel prices and supply cut-offs, and the reliance on fossil fuels releases CO2 emissions which contribute to climate change. Renewable energy expansion, facilitated by Morocco’s high potential for solar and wind capacity, could allow the country to improve its energy security and decarbonise its energy system, in line with its response to the Paris Agreement.

This study uses OSeMOSYS (the Open Source Energy Modelling System) to produce six cost-minimised decarbonisation scenarios for Morocco that consider energy independence. The results show that Morocco can achieve most of its decarbonisation targets through bulk wind and solar energy, with a coal phase-out being possible by 2031 at the latest. Natural gas is replaced by biomass and nuclear energy, with some evidence that fuel imports may stay relevant for the foreseeable future.

We conclude with policy recommendations. The study can provide insights for policymakers and stakeholders in Morocco's energy sector to achieve optimal pathways for decarbonisation.
Regarding the Gap between Prime Numbers
Authors: Thompson Daniel 
Published: May 2023

Abstract
Until now there is no efficient formula for determining the prime numbers. I show an efficient formula that takes only prime number values or multiples of 5, 7 and 11, and results in the successive prime number or a multiple of 5, 7 and 11. It is shown that by performing the same operation on a number that is a multiple of a prime number when using the formula will result in the next successive prime number value. The formula also identifies a pattern allowing mathematicians to begin at any random prime number and find the next successive prime number without fail. MSC: 11-xx
Reading intervention for students with intellectual disabilities without functional speech who require augmentative and alternative communication: A Multiple single-case design with four randomized baselines.
Authors: Ulriksen Line Britt , Bilet-Mossige Marthe , Moreira Hugo Cogo , Larsen Kenneth , Nordahl-Hansen Anders 
Published: May 2023

Abstract
Background: Literacy is one of the most important skills students can achieve, as it provides access to information and communication. Unfortunately, literacy skills are not easily acquired, especially for students with intellectual disabilities who require augmentative and alternative communication (AAC). There are many barriers to literacy acquisition, some due to low expectations from parents and teachers, lack of evidence-based reading programs and reading materials adapted for AAC. Barriers as a result of extensive support needs is also a real factor. This trial aims to deliver reading instructions to 40 students with intellectual disabilities who require AAC, and contribute in the debate on how to best support this population through reading instructions to maximizes their reading skills.
Methodology: 40 non verbal or minimally verbal students (age 6-14) with intellectual disabilities who require AAC will be part of a reading intervention with a multiple single-case design with four randomized baselines. The intervention period will last for 18 months, and will commence in March 2023. The students will receive the intervention in a one-to-one format, working systematically with a reading material that contains phonological awareness and decoding tasks based on the Accessible Literacy Leaning (ALL) developed by Janice Light and David McNaughton. All the teachers will be trained to deliver the reading intervention.
Discussion: The reading material “Lesing for alle” (Reading for all) is based on and follow the strategies behind the research of ALL. The current trial will through a reading intervention contribute to move beyond only teaching sight words and combine several reading component such as sound blending, letter sound correspondence, phoneme segmentation, shared reading, recognition of sight words and decoding. The strategies and methods in use is build on the existing science of reading, especially what has been effective in teaching reading for students with intellectual disabilities who require AAC. There is limited generalizability of prior findings in reading-related phonological processing interventions to different populations of they who use AAC specially outside of USA. More research is needed to understand how programs designed to improve reading skills across other settings, understand the program's long-term effects and to study the effectiveness when delivered by educators who are not speech language therapists or researchers.
Trial registration NCT05709405. Registered 23 January 2023,
Multivariate joint probability distributions for seismic design parameters across multiple building codes
Authors: Fuentes Nicolás , Flores Jorge , Egger Jorge , Vicencio Felipe , Aguilar Víctor , Yáñez Sergio 
Published: May 2023

Abstract
In order to contribute to the lack of statistical anomaly detection and sensibility procedures of the response parameters from international seismic codes, this study presents a comparative analysis between multiple Chilean codes for the seismic design of reinforced concrete buildings. The seismic response and its similar implications to the US codes are studied from a model of a reinforced concrete building in the city of Viña del Mar, Chile. The first study case is the NCh433 Of.96 Mod.2009, the second case is the NCh433 Of.96 Mod.2009 + D.S. 117 and 118, and the third case is the NCh433 Of.96 Mod.2009 + D.S. 60 and 61. The results show that the seismic response does not present great differences, but they show noticeable dependencies between multiple parameters within the three study cases. The third case presents the most oversized values of the response parameters, which require a design against a higher base shear. An analysis of the bio-seismic profile is included, which is a procedure commonly used for buildings in Chile, and its indexes are analyzed with statistical models that provide an easy overview of the data structure. Additionally, a pier wall with an opening, and a pier with a T-shaped wall are selected, which present an increase in the amount of reinforcing steel from the first code case to the third, and then to the second code case.
Single-cell resolution transcriptome atlases of soybean root organs reveal new regulatory programs controlling the nodulation process
Authors: Cervantes-Pérez Sergio Alan , Zogli Prince , Thibivilliers Sandra , Tennant Sutton , Hossain Md Sabbir , Xu Hengping , Meyer Ian , Nooka Akash , Subramanyam Sai Subhash Mahamkali Venkata , Ma Pengchong , Yao Qiuming , Naldrett Michael , Smith Benjamin , Bhattacharya Samik , Kläver Jasper , Libault Marc 
Published: May 2023

Abstract
The soybean root system is complex. In addition to being composed of various cell types, the soybean root system is also composed of the nodule, an organ in which mutualistic symbiosis with the nitrogen-fixing bacterium Bradyrhizobium diazoefficiens occurs. Notably, the soybean root nodule is characterized by a central infection zone where the atmospheric nitrogen is fixed and assimilated by the symbiont, resulting from the close cooperation between the plant cell and the bacteria. To date, the cellular complexity of the soybean root and nodule has not been characterized. Applying single nucleus RNA-seq technology, we characterized the transcriptomic signature of the soybean root and nodule cell types and revealed the existence of different sub-populations of B. diazoefficiens-infected cells in the soybean nodule including those actively involved or not in nitrogen fixation. The mining of the single cell-resolution atlas also helped reevaluate the role of known and identified new genes controlling the nodulation process. For instance, we functionally characterized the role of a new microdomain-associated GmFWL3 protein in the soybean nodule. Our study reveals the unique cellular complexity of the soybean nodule and helps redefine the concept of cell types when focusing on the infection zone of the nodule.
Filters of automobile air conditioning systems as in - car source of exposure to infections and toxic moulds
Authors: Gołofit-Szymczak Małgorzata , Wójcik-Fatla Angelina , Stobnicka-Kupiec Agata , Górny Rafał L. 
Published: May 2023

Abstract
The main part of the air condition system are air filters. The air conditioning system filters can turn overtime into the sources of in-car emission of microbiological hazards. The aim of this study was to quantitatively and qualitatively assess the presence of infectious and toxic fungi in the AC filters in passenger cars. The studied nonwoven filters were removed from passenger cars during “winter”/“summer” season. The taxonomic identification of the fungi isolated from the filters was performed using both the culture-based and molecular methods. RT-PCR was applied to assess the presence of gene fragments regulating aflatoxin biosynthesis in the isolates obtained from fungal cultures. The average fungal concentrations in the filter samples collected during the “summer” /“winter” season were 5.4x104cfu/m2 and 2.4x104cfu/m2, respectively. Most of the filter samples, collected in both the studied seasons revealed the presence of Aspergillus species including A. fumigatus, A. niger, A. terreus and/or A. flavus. The recorded levels of fungal contamination of AC filters in passenger cars indicate a necessity for a more frequent filter replacement in these type of vehicles. Occupational exposure to moulds and the resulting health problems that may be experienced by professional drivers should be properly recognized in order to undertake effective preventive measures.
Effects of seed traits on the cache size of a scatter-hoarding rodent, Leopoldamys edwardsi
Authors: Wang Minghui , Yang Xifu , Yi Xianfeng 
Published: May 2023

Abstract
Seed traits can influence post-dispersal seed fate and seedling establishment by manipulating the size of caches made by hoarding animals. However, few studies have explored how seed traits affect cache size and subsequent seed fate mediated by hoarding rodents. In this study, we investigated the effects of seed traits on hoarding behavior of Leopoldamys edwardsiusing seeds of Quercus variabilis, Castanea henryi, Camellia oleifera, Lithocarpus harlandii, and Choerospondias axillarisunder enclosures in Dujiangyan City, southwest China, in an attempt to elucidate the relationship between seed traits and cache size. Our results showed that there were significant differences in the scatter-hoarded preference among C. axillaris, C. henryi, C. oleifera, Q. variabilis and L. harlandii by L. edwardsi. There was a significant difference in the cache size between five seed species by L. edwardsi. More importantly, we found that there was a significant positive correlation between cache size and the proportion of intact after removal or crude fat, but a significant negativecorrelation between cache size and seed mass or crude starch. Our study has revealed that seed traits are a key factor in regulating the hoarding behavior of rodents, which includes the size of their caches. This behavior, in turn, has a significant impact on the fate of the seeds and the growth of seedlings that emerge from the caches.
Significance statement
At present, a large number of studies focus on a certain trait of a single seed or the effect of a certain seed trait of various seeds on the hoarding behavior of rodents, but how seed traits affect cache size and subsequent seed fate mediated by hoarding rodents remains unknown. This study systematically illustrates how rodents build storage sites and determine the seed fates according to seed traits. Establishing food storage sites based on different seed traits involves a trade-off between the recovery rate and the pilfering rate of food-hoarding sites, which may be an adaptive storage strategy formed in the long-term evolution process.
Modified approaches to solve matrix games with payoffs of single-valued trapezoidal neutrosophic numbers
Authors: Kirti Kirti , Verma Tina , Kumar Amit 
Published: May 2023

Abstract
Seikh and Dutta (Soft Computing (2022) 26:921–936) pointed out that there does not exist any approach to solve single-valued trapezoidal neutrosophic (SVTN) matrix games (matrix games in which each payoff is represented by a SVTN number). To fill this gap, Seikh and Dutta proposed two approaches to solve SVTN matrix games. Brikaa (Soft Computing (2022) 26:9137–9139) pointed out that it is inappropriate to use Seikh and Dutta’s first approach as a mathematically incorrect result is considered in it. Brikaa also modified Seikh and Dutta’s first approach to resolve its inappropriateness. In this paper, it is pointed out that it is also inappropriate to use Brikaa’s approach as some mathematically incorrect results are considered in it. Also, it is pointed out that it is inappropriate to use Seikh and Dutta’s second approach as a mathematically incorrect result is considered in it. Furthermore, Brikaa’s approach and Seikh and Dutta’s second approach are modified to resolve their inappropriateness. Finally, the correct results of a SVTN matrix game, considered by Seikh and Dutta to illustrate their proposed approaches, are obtained by the modified approaches.