bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does surgency moderate the relationship between parenting and children's aggression in middle childhood?
Authors: Ruiz‐Ortiz Rosa , Braza Paloma , Carreras Rosario , Muñoz José Manuel 
Published: December 2022

AbstractParenting and child temperament have both been linked to aggression among children. This study explores the moderating effects of children's surgency and sex and paternal/maternal parenting practices on aggressive behaviour in middle childhood. We analyse whether the moderating effects observed fit a Diathesis‐Stress, Differential Susceptibility or Vantage Sensitivity model. Participants were 203 school children aged 7–8 years (M = 92.42 months, SD = 3.52) from southern Spain. Maternal inconsistency and coercion and paternal hostility and indulgence, had a direct effect on children's aggressive behaviour. The effects of maternal hostility and anticipatory problem solving on children's aggression were moderated by surgency (Diathesis‐Stress), as was the effect of paternal coercion on aggression (Vantage Sensitivity). Children's sex was not found to moderate any effect. It therefore seems that not all children are equally sensitive to the influence of parenting on their aggression levels, and that this influence depends on their temperament.Highlights
This study explores the moderating effects of children's surgency and sex and paternal/maternal parenting practices on aggressive behavior.
Children's surgency moderated the effect of maternal hostility and anticipatory problem solving on children's aggression, with both effects fitting a Diathesis‐Stress model.
Children's surgency moderated the effect of paternal coercion on children's aggression, with this effect fitting a Vantage Sensitivity model.
Impact of return and volatility spillover from banking industry to other industries: An evidence from Pakistan
Authors: Mir Fahad Waqas , Bhutta Nousheen Tariq 
Published: December 2022

AbstractThis article aims to examine the transmission of return and volatility spillover from the banking industry to other industries in Pakistan. The study uses daily stock prices from 2005 to 2018 from the financial and non‐financial sectors listed at Pakistan stock exchange. The KSE‐100 index is used as a basis for the selection he industries and companies. The banking stock return ARMA‐GARCH in mean model is used to measure the return and volatility spillover. The time‐varying conditional correlation and asymmetric effect are explored using the DDC and ADDC models. Return and volatility spillover are found across the various industries during the period, indicating limited evidence of diversification. The DCC‐GARCH model shows that there is a time‐varying conditional correlation and asymmetric behaviour of the data.
Interactions between ultrasonographic cervical length and placenta accreta spectrum on severe postpartum hemorrhage in women with placenta previa
Authors: Dang Xiaohe , Fan Cuifang , Cui Feipeng , He Yi , Sun Guoqiang , Ruan Jinghan , Fan Yilin , Lin Xingguang , Wu JianLi , Liu Yanyan , Wang Shaoshuai , Bao Yindi , Xu Jie , Du Hui , Chen Suhua , Deng Dongrui , Qiao Fuyuan , Zeng Wanjiang , Feng Ling , Liu Haiyi 
Published: December 2022

AbstractObjectiveTo explore the interactions between cervical length (CL) and placenta accreta spectrum (PAS) on severe postpartum hemorrhage (SPPH) in patients with placenta previa.MethodsA retrospective case–control study was conducted at four medical centers in China, and 588 patients with placenta previa were included. The logistic regression analysis and restricted cubic splines (RCS) were used to evaluate the association between CL and SPPH. Furthermore, the joint effect of CL and PAS on SPPH was assessed, and the additive and multiplicative interactions were calculated.ResultsAfter adjusting for potential confounders, the negative linear dose–response relationship was confirmed by RCS, and the change of odds ratio (OR) was more significant when CL was 2.5 cm or less. The risk of SPPH was significantly higher when CL of 2.5 cm or less co‐existed with placenta increta/percreta than when CL of 2.5 cm less, or placenta increta/percreta existed alone (adjusted OR [aOR]CL ≤2.5cm&placenta accreta/non‐PAS3.40, 95% confidence interval [CI] 1.37–8.45; aORplacenta increta/percreta&CL >2.5cm4.75, 95% CI 3.03–7.47; aORCL ≤2.5cm&placenta increta/percreta14.51, 95% CI 6.08–34.64), and there might be additive interaction between CL and placenta increta/percreta on SPPH (attributable proportion due to interaction 50.7%, 95% CI 6.1%–95.3%).ConclusionIf CL was routinely performed during PAS evaluation, the increased OR of short CL and PAS could allow better patient preparation through counseling.
Osteogenic capacity of octacalcium phosphate involving macrophage polarization
Authors: Xiao Linghao , Shiwaku Yukari , Hamai Ryo , Baba Kazuyoshi , Tsuchiya Kaori , Imazato Satoshi , Sasaki Keiichi , Suzuki Osamu 
Published: December 2022

AbstractPrevious research has found that octacalcium phosphate (OCP) increases macrophage accumulation and alters the initial inflammatory response. However, the role of the immune response induced by OCP in osteogenesis remains unknown. This study investigated the behavior of macrophages and bone regeneration capacity during the early inflammatory stage of OCP‐mediated osteogenesis. To assess the change in macrophage polarization and osteogenic capacity, we used a standardized rat defect model filled with OCP or calcium‐deficient hydroxyapatite (CDHA)—a material obtained through the hydrolysis of the original OCP. OCP or CDHA granules were incubated with RAW264 cells for 5 days to investigate the effect of physicochemical characteristics on macrophage cytokine/chemokine expression in vitro. Our in vivo results show that due to the OCP implantation, macrophages in the rat tibial defect area tend to polarize to the M2 phenotype (anti‐inflammatory) and inhibit the formation of the M1 phenotype (pro‐inflammatory). In comparison to CDHA, OCP exhibited superior bone regeneration potential due to its rapid promotion of cortical bone healing and stimulation of macrophage‐related growth factors. Furthermore, our in vitro results have shown that OCP regulates the expression of macrophage chemokines over time. Compared to incubation with CDHA, incubation with OCP caused changes in the ionic microenvironment. These findings suggest that the OCP‐mediated macrophage polarization and secretion profile not only regulate immune function but also positively affect osteogenesis.
Voltammetric and spectroscopic studies of water/formamide ratios in the production of the cerium (III) hexacyanoferrate (II) nanoparticles
Authors: do Carmo Devaney Ribeiro , de Oliveira Denys Ribeiro 
Published: December 2022

AbstractThe present study describes the simple and fast preparation of Cerium (III) hexacyanoferrate (II) (CeHCF) solid nanoparticles at three different water/formamide (%) ratios used as solvent (v/v) (100:0, 80:20, 0:100). CeHCF nanoparticles (Nps) were characterized by fourier transform infrared pectroscopy (FTIR), x‐ray diffraction (XRD), scanning electron microscopy (SEM), zeta potential and cyclic voltammetry (CV). Electrodes modified with CeHCF presented a well‐defined redox pair with formal potential (Eo′) of approximately 0.29 V (vs. Ag/AgCl(sat) attributed to the Fe2 +/Fe3+ redox pair in the presence of cerium (III)). The Nps in the three systems investigates, presents a random size distribution to different surface, where most were distributed between 20 and 160 nm. Considering the three investigated systems, only CeHCF‐1 (100:0) was sensitive to L‐dopamine, presenting a linear signal region as a function of L‐dopamine concentrations, with a limit of detection (LD) of 0.125 mmol L−1, limit of quantification (LQ) of 0.419 mmol L−1 and amperometric sensitivity (S) of 148.16 μA mmol L−1.
Antimicrobial resistance and biofilm formation capacity among Acinetobacter baumannii strains isolated from patients with burns and ventilator‐associated pneumonia
Authors: Khoshnood Saeed , Sadeghifard Nourkhoda , Mahdian Nahid , Heidary Mohsen , Mahdian Somayeh , Mohammadi Maryam , Maleki Abbas , Haddadi Mohammad Hossein 
Published: December 2022

AbstractBackgroundAcinetobacter baumannii is a pathogen responsible for nosocomial infections, especially in patients with burns and ventilator‐associated pneumonia (VAP). The aims of this study was to compare the biofilm formation capacity, antimicrobial resistance patterns and molecular typing based on PFGE (Pulsed‐Field Gel Electrophoresis) in A. baumannii isolated from burn and VAP patients.Materials and MethodsA total of 50 A. baumannii isolates were obtained from burn and VAP patients. In this study, we assessed antimicrobial susceptibility, biofilm formation capacity, PFGE fingerprinting, and the distribution of biofilm‐related genes (csuD, csuE, ptk, ataA, and ompA).ResultsOverall, 74% of the strains were multidrug resistant (MDR), and 26% were extensively drug‐resistant (XDR). Regarding biofilm formation capacity, 52%, 36%, and 12% of the isolates were strong, moderate, and weak biofilm producers. Strong biofilm formation capacity significantly correlated with XDR phenotype (12/13, 92.3%). All the isolates harbored at least one biofilm‐related gene. The most prevalent gene was csuD (98%), followed by ptk (90%), ataA (88%), ompA (86%), and csuE (86%). Harboring all the biofilm‐related genes was significantly associated with XDR phenotype. Finally, PFGE clustering revealed 6 clusters, among which cluster No. 2 showed a significant correlation with strong biofilm formation and XDR phenotype.ConclusionOur findings revealed the variable distribution of biofilm‐related genes among MDR and XDR A. baumannii isolates from burn and VAP patients. A significant correlation was found between strong biofilm formation capacity and XDR phenotype. Finally, our results suggested that XDR phenotype was predominant among strong‐biofilm producer A. baumannii in our region.
Photocatalytic treatment as a polishing step for the degradation of bio‐recalcitrant fractions of winery wastewater under solar, UVA‐LED, and blacklight irradiation
Authors: Davididou Konstantina , Vakros John , Frontistis Zacharias 
Published: December 2022

AbstractBACKGROUNDThis study investigates, for the first time, the most beneficial conditions for photocatalytic oxidation under ultraviolet (UV) irradiation provided by either a solar simulator, UVA light‐emitting diode (UVA‐LED), or UVA blacklight lamp (UVA‐BL) as a post‐treatment step for the degradation of the residual COD and color in winery wastewater (WiWW) after biological treatment.RESULTSThe effect of WiWW dilution (0, 50%), TiO2 concentration (0–1000 mg/L), catalyst type (TiO2, ZnO), pH (3, 6, 8.4), H2O2 addition (0–1000 mg/L), and treatment time on process efficiency was evaluated. At the best‐assayed conditions (1000 mg/L TiO2, 1000 mg/L H2O2), COD removal percentages in the range of 94–97% were obtained and color was removed by 99% within 180 min of treatment under all irradiation sources. The process was enhanced when the WiWW was subjected to 50% dilution and its pH was adjusted to 6. Among the three irradiation sources, UVA‐BL led to a marginally higher photocatalytic performance than solar and UVA‐LED, both of which achieved similar removal efficiencies. Regarding energy efficiency, UVA‐LED was found to be up to 1.7 times more energy efficient than UVA‐BL/TiO2. Finally, in most cases, the phytotoxicity of secondary effluent was eliminated during solar photocatalytic treatment.CONCLUSIONAlteration of basic operating parameters significantly improved process efficiency. In all cases, LED‐driven photocatalysis combined high removal performance and energy efficiency, proving to be an appropriate and sustainable alternative to solar photocatalysis for 24 h operation or for supplementary application during the harvest, when the majority of WiWW is generated. © 2022 Society of Chemical Industry (SCI).
Effects of prenatal testosterone exposure on the development of autism‐like behaviours in offspring of Wistar rats
Authors: Erdogan Mumin Alper , Bozkurt Mehmet Fatih , Erbas Oytun 
Published: December 2022

AbstractBackgroundA neurodevelopmental disease, autism spectrum disorder (ASD) occurs in males three times more commonly than girls. Higher prenatal testosterone exposure may result in autistic‐like behaviour in boys, according to earlier research. It is unclear how fetal testosterone affects the development of autism. In this study, we tested the hypothesis that prenatal testosterone exposure in an animal model may result in autistic behaviours by modifying serotonin, dopamine, IGF‐1 and oxytocin levels.Materials and MethodsGroup 1 (control, n = 6) and Group 2 (testosterone undecanoate, n = 6) of female rats were randomly assigned. For 2–3 days during the oestrus cycle, female rats were housed with a reproductive male (three females/one male). On the 10th day of gestation, rats in Group 1 received 1 ml/kg% 0.9 NaCl saline, whereas rats in Group 2 received 250 mg/kg testosterone undecanoate. Until weaning on postnatal day 21 (P21), the mothers were permitted to care for their pups. On P21, 40 littermates—10 male and female for control and 10 male and female from mothers that exposed to testosterone—were arbitrarily split up and housed. On P50, these mature rats were tested for their behaviour. The rats were then sacrificed. The brain tissue was subjected to histological examinations as well as biochemical tests for homovanillic acid (HVA), 5‐Hydroxyindoleacetic acid (5‐HIAA), oxytocin and insulin‐like growth factor‐1 (IGF‐1).ResultsThe groups differed significantly in the behavioural examinations (three‐chamber social test, passive avoidance learning analysis, open field test), with the testosterone‐exposed groups exhibiting autistic symptoms to a higher extent. When compared with the control groups, testosterone exposure caused significant histological changes in the hippocampus CA1 and CA3 areas, including gliosis and cell death of neurons. In the testosterone‐exposed groups, HVA, 5‐HIAA and IGF‐1 tissue expressions in the brain elevated, whereas oxytocin levels reduced. These findings point to a potential connection between neurodevelopmental disorders like ASD and exposure to testosterone during gestation.ConclusionOverall, we revealed that prenatal testosterone exposure led to autistic traits by elevating serotonin, dopamine and IGF‐1 levels while lowering oxytocin levels.
Successful combination treatment with azacitidine and venetoclax as a bridging therapy for third allogenic stem cell transplantation in a patient with 11q23/MLL‐rearranged complex karyotype acute myeloid leukemia
Authors: Edahiro Taro , Ureshino Hiroshi , Chishaki Ren , Fujino Keita , Mino Tatsuji , Yoshida Tetsumi , Fukushima Noriyasu , Ichinohe Tatsuo 
Published: December 2022

AbstractTranslocation t(6;11) occurs in approximately 5% of patients with acute myeloid leukemia (AML) corresponding to 11q23/mixed lineage leukemia (MLL) rearrangement. The AF6 gene on chromosome 6q27 is the fusion partner of the MLL gene on 11q23 in t(6;11), which results in a poor prognosis. The case of a patient with 11q23/MLL‐rearranged AML who successfully underwent a third allogeneic stem cell transplantation after treatment with azacitidine (AZA) and venetoclax (VEN) is presented in this article. This report suggests that a combination of AZA and VEN is an effective therapeutic approach for relapsed and refractory MLL‐rearranged AML.
Interactions between polycyclic musks and human lactoferrin: Multi‐spectroscopic methods and docking simulation
Authors: Shi Mengjie , He Jinfeng , Xu Minhua , Lin Xiaolian , Liu Hongyan , Jiang Tiemin , Yi Zhongsheng 
Published: December 2022

AbstractGalaxolide (1,3,4,6,7,8‐hexahydro‐4,6,6,7,8‐hexamethylcyclopenta‐γ‐2‐benzopyrane; HHCB) and Tonalide (7‐acetyl‐1,1,3,4,4,6‐hexamethyl‐1,2,3,4‐tetrahydronaphthalene; AHTN) are “pseudo‐persistent” pollutants that can cause DNA damage, endocrine disruption, organ toxicity, and reproductive toxicity in humans. HHCB and AHTN are readily enriched in breast milk, so exposure of infants to HHCB and AHTN is of concern. Here, the molecular mechanisms through which HHCB and AHTN interact with human lactoferrin (HLF) are investigated using computational simulations and spectroscopic methods to identify indirectly how HHCB and AHTN may harm infants. Molecular docking and kinetic simulation studies indicated that HHCB and AHTN can interact with and alter the secondary HLF structure. The fluorescence quenching of HLF by HHCB, AHTN was static with the forming of HLF‐HHCB, HLF‐AHTN complex, and accompanied by non‐radiative energy transfer and that 1:1 complexes form through interaction forces. Time‐resolved fluorescence spectroscopy indicated that binding to small molecules does not markedly change the HLF fluorescence lifetime. Three‐dimensional fluorescence spectroscopy indicated that HHCB and AHTN alter the peptide chain backbone structure of HLF. Ultraviolet‐visible absorption spectroscopy, simultaneous fluorescence spectroscopy, Fourier‐transform infrared spectroscopy, and circular dichroism spectroscopy indicated that HHCB and AHTN change the secondary HLF conformation. Antimicrobial activity experiments indicated that polycyclic musks decrease lactoferrin activity and interact with HLF. These results improve our understanding of the mechanisms involved in the toxicities of polycyclic musks bound to HLF at the molecular level and provide theoretical support for mother‐and‐child health risk assessments.
Multivendor Evaluation of Automated MRI Postprocessing of Biventricular Size and Function for Children With and Without Congenital Heart Defects
Authors: van der Ven Jelle P. G. , van Genuchten Wouter , Sadighy Zaheda , Valsangiacomo Buechel Emanuela R. , Sarikouch Samir , Boersma Eric , Helbing Willem A. 
Published: December 2022

BackgroundManually segmenting cardiac structures is time‐consuming and produces variability in MRI assessments. Automated segmentation could solve this. However, current software is developed for adults without congenital heart defects (CHD).PurposeTo evaluate automated segmentation of left ventricle (LV) and right ventricle (RV) for pediatric MRI studies.Study TypeRetrospective comparative study.PopulationTwenty children per group of: healthy children, LV‐CHD, tetralogy of Fallot (ToF), and univentricular CHD, aged 11.7 [8.9–16.0], 14.2 [10.6–15.7], 14.6 [11.6–16.4], and 12.2 [10.2–14.9] years, respectively.Sequence/Field StrengthBalanced steady‐state free precession at 1.5 T.AssessmentBiventricular volumes and masses were calculated from a short‐axis stack of images, which were segmented manually and using two fully automated software suites (Medis Suite 3.2, Medis, Leiden, the Netherlands and SuiteHeart 5.0, Neosoft LLC, Pewaukee, USA). Fully automated segmentations were manually adjusted to provide two further sets of segmentations. Fully automated and adjusted automated segmentation were compared to manual segmentation. Segmentation times and reproducibility for each method were assessed.Statistical TestsBland Altman analysis and intraclass correlation coefficients (ICC) were used to compare volumes and masses between methods. Postprocessing times were compared by paired t‐tests.ResultsFully automated methods provided good segmentation (ICC > 0.90 compared to manual segmentation) for the LV in the healthy and left‐sided CHD groups (eg LV‐EDV difference for healthy children 1.4 ± 11.5 mL, ICC: 0.97, for Medis and 3.0 ± 12.2 mL, ICC: 0.96 for SuiteHeart). Both automated methods gave larger errors (ICC: 0.62–0.94) for the RV in these populations, and for all structures in the ToF and univentricular CHD groups. Adjusted automated segmentation agreed well with manual segmentation (ICC: 0.71–1.00), improved reproducibility and reduced segmentation time in all patient groups, compared to manual segmentation.Data ConclusionFully automated segmentation eliminates observer variability but may produce large errors compared to manual segmentation. Manual adjustments reduce these errors, improve reproducibility, and reduce postprocessing times compared to manual segmentation. Adjusted automated segmentation is reasonable in children with and without CHD.Evidence Level3.Technical EfficacyStage 2.
Non‐Contrast‐Enhanced MR Arteriography of Potential Living‐Related Liver Donor: Using Contrast Enhanced CT Arteriography as Standard Reference
Authors: Lin Wei‐Ching , Chen Chun‐Ming , Westphalen Antonio Carlos , Lin Tzu‐Yang , Chang Chia Hao , Chen Li‐Kuang , Lin Chia‐Wei , Yeh Chun‐Chieh , Yu Jiaxin , Jeng Long‐Bin , Chen Jeon‐Hor 
Published: December 2022

BackgroundContrast‐enhanced computed tomography angiography (CTA) and magnetic resonance angiography (MRA) are the primary modalities to assess donors' vessels before transplant surgery. Radiation and contrast medium are potentially harmful to donors.PurposeTo compare the image quality and visualization scores of hepatic arteries on CTA and balanced steady‐state free‐precession (bSSFP) non‐contrast‐enhanced MRA (NC‐MRA), and to evaluate if bSSFP NC‐MRA can potentially be a substitute for CTA.Study TypeProspective.PopulationFifty‐six consecutive potential living‐related liver donors (30.9 ± 8.4 years; 31 men).Field Strength/Sequence1.5T; four bSSFP NC‐MRA sequences: respiratory‐triggered (Inhance inflow inversion recovery [IFIR]) and three breath‐hold (BH); and CTA.AssessmentThe artery‐to‐liver contrast (Ca‐l) was quantified. Three radiologists independently assigned visualization scores using a four‐point scale to potential origins, segments, and branches of the hepatic arteries, determined the anatomical variants based on Hiatt's classification, and assessed the image quality of NC‐MRA sequences.Statistical TestsFleiss' kappa to evaluate the readers' agreement. Repeat measured ANOVA or Friedman test to compare Ca‐l of each NC‐MRA. Friedman test to compare overall image quality and visualization scores; post hoc analysis using Wilcoxon signed‐rank test. P‐value <0.05 was considered statistically significant.ResultsInhance IFIR Ca‐l was significantly higher than all BH bSSFP Ca‐l (0.56 [0.45–0.64] vs. 0.37 [0.29–0.47] to 0.41 [0.23–0.51]). Overall image quality score of BH bSSFP TI1200 was significantly higher than other NC‐MRA (4 [4–4] vs. 4 [3 to 4–4]). The median visualization scores of almost all arteries on CTA were significantly higher than on NC‐MRA (4 [3 to 4–4] vs. 1 [1–2] to 4 [4–4]). The median visualization scores were all 4 [4–4 ] on Inhance IFIR with >92.3% observed scores ≥3, except the segment 4 branch (3 [1–4], 53.6%). The identification rates of arterial variants were 92.9%–97% on Inhance IFIR.Data ConclusionsAlthough CTA is superior to the NC‐MRA, all NC‐MRA depict the donor arterial anatomy well. Inhance IFIR can potentially be an alternative image modality for CTA to evaluate the arterial variants of living donors.Level of Evidence3Technical EfficacyStage 2
Scale‐separation diagnostics and the Symmetric Bounded Efficiency for the inter‐comparison of precipitation reanalyses
Authors: Casati Barbara , Lussana Cristian , Crespi Alice 
Published: December 2022

AbstractThe ERA5 global reanalysis has been compared against a high‐resolution regional reanalysis (COSMO‐REA6) by means of scale‐separation diagnostics based on 2d Haar discrete wavelet transforms. The presented method builds upon existing methods and enables the assessment of bias, error and skill for individual spatial scales, separately. A new skill score (evaluated against random chance) and the Symmetric Bounded Efficiency are introduced. These are compared to the Nash‐Sutcliffe and the Kling‐Gupta Efficiencies, evaluated on different scales, and the benefits of symmetric statistics are illustrated. As expected, the wavelet statistics show that the coarser resolution ERA5 products underestimate small‐to‐medium scale precipitation compared to COSMO‐REA6. The newly introduced skill score shows that the ERA5 control member (EA‐HRES), despite its higher variability, exhibits better skill in representing small‐to‐medium scales with respect to the smoother ensemble members. The Symmetric Bounded Efficiency is suitable for the inter‐comparison of reanalyses, since it is invariant with respect to the order of comparison.