bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine learning models based on clinical indices and cardiotocographic features for discriminating asphyxia fetuses—Porto retrospective intrapartum study
Authors: Ribeiro Maria , Nunes Inês , Castro Luísa , Costa-Santos Cristina , S. Henriques Teresa 
Published: March 2023

IntroductionPerinatal asphyxia is one of the most frequent causes of neonatal mortality, affecting approximately four million newborns worldwide each year and causing the death of one million individuals. One of the main reasons for these high incidences is the lack of consensual methods of early diagnosis for this pathology. Estimating risk-appropriate health care for mother and baby is essential for increasing the quality of the health care system. Thus, it is necessary to investigate models that improve the prediction of perinatal asphyxia. Access to the cardiotocographic signals (CTGs) in conjunction with various clinical parameters can be crucial for the development of a successful model.ObjectivesThis exploratory work aims to develop predictive models of perinatal asphyxia based on clinical parameters and fetal heart rate (fHR) indices.MethodsSingle gestations data from a retrospective unicentric study from Centro Hospitalar e Universitário do Porto de São João (CHUSJ) between 2010 and 2018 was probed. The CTGs were acquired and analyzed by Omniview-SisPorto, estimating several fHR features. The clinical variables were obtained from the electronic clinical records stored by ObsCare. Entropy and compression characterized the complexity of the fHR time series. These variables' contribution to the prediction of asphyxia perinatal was probed by binary logistic regression (BLR) and Naive-Bayes (NB) models.ResultsThe data consisted of 517 cases, with 15 pathological cases. The asphyxia prediction models showed promising results, with an area under the receiver operator characteristic curve (AUC) &gt;70%. In NB approaches, the best models combined clinical and SisPorto features. The best model was the univariate BLR with the variable compression ratio scale 2 (CR2) and an AUC of 94.93% [94.55; 95.31%].ConclusionBoth BLR and Bayesian models have advantages and disadvantages. The model with the best performance predicting perinatal asphyxia was the univariate BLR with the CR2 variable, demonstrating the importance of non-linear indices in perinatal asphyxia detection. Future studies should explore decision support systems to detect sepsis, including clinical and CTGs features (linear and non-linear).
Ocular biological parameters and prevalence of myopia in vocational high school and general high school in China
Authors: Liu Yang , Meng Dexin , Wang Yun , Wang Xuechun , Xue Caihong , Hao Rui , Zhang Wei 
Published: March 2023

SignificanceHigher prevalence of myopia is possibly associated with more extended schooling schedules. Therefore, adjustments to high school curricula may aid in reducing the prevalence of myopia among adolescents.PurposeTo investigate the prevalence of myopia among 15- to 18-year-old adolescents in Tianjin, China, and to evaluate the impact of different educational schedules on the prevalence of myopia among high school students.MethodsThis is a school-based epidemiological study with a cross-sectional design. Ocular biological parameters and noncycloplegic photorefraction were examined using optical biometry devices and photoscreener devices. Each student’s spherical equivalent (SE) and ocular biometry were recorded, and the prevalence of myopia was calculated.ResultsA total of 2,867 participants (1,519 males and 1,348 females) were tested for non-cycloplegic refraction, axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD) and lens thickness (LT). In this research, the overall prevalence of myopia was 81.6%, with high myopia accounting for 11.8%. Myopia prevalence was substantially higher in general high schools than in vocational high schools, with 86.1 and 70.1%, respectively. There were no significant differences in the prevalence of myopia (p = 0.744) or high myopia (p = 0.851) across the three vocational school years. In the general high school, however, there was an increase of 4.6% (p &lt; 0.05) in myopia prevalence between year 10 and year12.ConclusionComparing vocational and standard high school students, there are considerable disparities in prevalence of myopia, spherical equivalent, and ocular biological parameters. The prevalence of myopia and high myopia increased among standard high school students, but remained relatively consistent among students in vocational schools.
Profile and characteristics of the adequacy of blood transfusions in Trauma Intensive Care. A cross sectional multicenter study
Authors: Juárez-Vela Raúl , Quintana-Diaz Manuel , Rodríguez-Calvo Antonio , Santos-Sánchez José Ángel , Gero-Escapa María , Gallego-Curto Elena , Satústegui-Dordá Pedro José , Sánchez-González Juan Luis , Jericó Carlos , Ruiz de Viñaspre-Hernández Regina , Gil-Fernández Guadalupe , García-Erce José Antonio 
Published: March 2023

IntroductionMajor trauma is one of the major health care problems facing modern society, trauma systems require careful planning to achieve an ideal level of coverage for the population. The Patient Blood Management Program is an integrated and global strategy to provide patient care that aims to assess and address, when possible, the etiology of blood abnormalities rather than transfuse without treating the underlying cause. We aimed to describe the factors that are associated with the clinical decision to transfuse polytraumatized patients admitted to the Intensive Care Unit (ICU).MethodWe performed a cross sectional multicenter study of patients admitted to ICUs for trauma in 14 Spanish hospitals from September 2020 to December 2021.ResultsA total of 69 patients were treated in the emergency room due to polytrauma, 46% of them were considered serious in the initial triage. Thirty were caused by a fall from considerable height (43.47%), followed by 39 patients admitted due to trac accidents (56.52%). The location of the trauma was mainly cranioencephalic, followed by thoracic trauma. Of the 69 patients, 25 received a blood transfusion during their ICU stay (36.23%).DiscussionNo significant differences were observed between transfused and non-transfused patients, except for the severity scales, where transfused patients have a higher score on all the scales assessed in the ICU except for the Revised Trauma Score. As we can see, the incidence of kidney failure was also different between the groups analyzed, reaching 44.00% in transfused patients and 13.64% in the group of patients without blood transfusion, p = 0.005. In this sense, 92.00% of the transfusions performed were inadequate according to the criteria of Hb in blood prior to the decision to transfuse (Hb &lt; 9). Our data support the need to consider clinical practice guidelines regarding blood transfusion and its practices.
Evaluation of YouTube videos addressing thoracoscopic sympathectomy using the LAP-VEGaS guidelines
Authors: Adorisio Ottavio , Davoli Enrico , De Peppo Francesco 
Published: March 2023

IntroductionThe study aims to evaluate the quality of videos addressing thoracoscopic sympathectomy on YouTube® using the LAParoscopic surgery Video Educational GuidelineS (LAP-VEGaS) criteria.MethodsYouTube was searched using the following keyword: “thoracoscopic sympathectomy” on August 22, 2021. The first 50 videos were analyzed and classified for baseline characteristics and conformity to the LAP-VEGaS checklist.ResultsDuration ranged from 19 s to 22 min. The mean number of likes was 14.8 (range 0–80). The mean number of dislikes was 2.5 (range 0–14). The mean number of comments was 8.5 (range 0–67). Nineteen videos did not meet our criteria and were excluded. Regarding the remaining 31 videos, none contained all 16 points of the LAP-VEGaS essential checklist (mean 5.4 points, range 2–14 points), with almost all neglecting preoperative information and outcomes. The mean percentage of conformity was 37% (range 12%–93%). The most viewed videos were not associated with higher conformity to LAP-VEGaS criteria showing only 4/16 points (25%).ConclusionsThe quality of videos addressing TS on YouTube®, based on the LAP-VEGaS checklist may be considered not acceptable. Experienced surgeons and surgeons in trainees should be aware of this when using it as a learning resource in their clinical practice.
Antimicrobial Resistance Molecular Mechanisms of Helicobacter pylori in Jordanian Children: A Cross-Sectional Observational Study
Authors: Burayzat Salma , Al-Tamimi Mohammad , Barqawi Mohammad , Massadi Mustafa Sabri , Abu-Raideh Jumanah , Albalawi Hadeel , Khasawneh Ashraf I. , Himsawi Nisreen , Barber Maha 
Published: March 2023

Background: H. pylori antimicrobial resistance causes increasing treatment failure rates among H. pylori gastritis in children. This study investigates the molecular mechanisms of H. pylori antimicrobial resistance among Jordanian children. Methods: Demographic, clinical, and laboratory data were recorded for children referred to Prince Hamzah Hospital. Clarithromycin, Metronidazole, and Levofloxacin susceptibility were tested via E-test. Clarithromycin-related mutations were investigated using Real-Time (RT)-PCR and Levofloxacin resistance was analyzed with DNA sequencing of the gyrA gene. Results: 116 children were recruited, including 55.2% females and 55.2% in the age range of 10.1 to 14 years. A total of 82.7% were naïve to eradication therapy. H. pylori positivity was 93.9%, 89.6%, 61.7%, and 84.3% according to Rapid Urease Test, histology, culture, and RT-PCR, respectively. Resistance rates were 25.9% for Clarithromycin, 50% for Metronidazole, and 6.9% for Levofloxacin via E-test. A2142G or A2143G or a combination of both mutations concerning Clarithromycin resistance were documented in 26.1% of samples, while mutations in gyrA gen-related to Levofloxacin resistance were reported in 5.3% of samples. Antibiotic resistance was significantly affected by abdominal pain, anemia, hematemesis, and histological findings (p < 0.05). Conclusion: H. pylori resistance was documented for Metronidazole and Clarithromycin. RT-PCR for H. pylori identification and microbial resistance determination are valuable alternatives for cultures in determining antimicrobial susceptibility.
Outlier Detection in Time-Series Receive Signal Strength Observation Using Z-Score Method with Sn Scale Estimator for Indoor Localization
Authors: Yaro Abdulmalik Shehu , Maly Filip , Prazak Pavel 
Published: March 2023

Collecting time-series receive signal strength (RSS) observations and averaging them is a common method for dealing with RSS fluctuation. However, outliers in the time-series observations affect the averaging process, making this method less efficient. The Z-score method based on the median absolute deviation (MAD) scale estimator has been used to detect outliers, but it is only efficient with symmetrically distributed observations. Experimental analysis has shown that time-series RSS observations can have a symmetric or asymmetric distribution depending on the nature of the environment in which the measurement was taken. Hence, the use of the Z-score method with the MAD scale estimator will not be efficient. In this paper, the Sn scale estimator is proposed as an alternative to MAD to be used with the Z-score method in detecting outliers in time-series RSS observations. Performance comparison using an online RSS dataset shows that the Z-score with MAD and Sn as scale estimators falsely detected about 50% and 13%, respectively, of the RSS observations as outliers. Furthermore, the average absolute RSS median deviations between raw and outlier-free observations are 3 dB and 0.25 dB, respectively, for the MAD and Sn scale estimators, corresponding to a range error of about 2 m and 0.5 m.
Globisporangium and Pythium Species Associated with Yield Decline of Pyrethrum (Tanacetum cinerariifolium) in Australia
Authors: Liu Yuzhu , Vaghefi Niloofar , Ades Peter K. , Idnurm Alexander , Ahmed Aabroo , Taylor Paul W. J. 
Published: March 2023

Pyrethrum (Tanacetum cinerariifolium) cultivation in Australia, which accounts for the majority of global production of natural insecticidal pyrethrins, is affected by a persistent yield decline which in part is caused by a complex of pathogens. Globisporangium and Pythium species were isolated from crown and roots of pyrethrum plants showing stunting and brown discoloration of crown tissue, and from soil adjacent to diseased plants from yield-decline-affected sites in Tasmania and Victoria, Australia. Ten known Globisporangium species (Globisporangium attrantheridium, G. erinaceum, G. intermedium, G. irregulare, G. macrosporum, G. recalcitrans, G. rostratifingens, G. sylvaticum, G. terrestris and G. ultimum var. ultimum), two new Globisporangium species (Globisporangium capense sp. nov. and Globisporangium commune sp. nov.) and three Pythium species (Pythium diclinum/lutarium, P. tracheiphilum and P. vanterpoolii) were identified through morphological studies and multigene phylogenetic analyses using ITS and Cox1 sequences. Globisporangium ultimum var. ultimum, G. sylvaticum, G. commune sp. nov. and G. irregulare were most abundant. Globisporangium attrantheridium, G. macrosporum and G. terrestris were reported for the first time in Australia. Seven Globisporangium species were pathogenic on both pyrethrum seeds (in vitro assays) and seedlings (glasshouse bioassays), while two Globisporangium species and three Pythium species only caused significant symptoms on pyrethrum seeds. Globisporangium irregulare and G. ultimum var. ultimum were the most aggressive species, causing pyrethrum seed rot, seedling damping-off and significant plant biomass reduction. This is the first report of Globisporangium and Pythium species causing disease in pyrethrum globally and suggests that oomycete species in the family Pythiaceae may have an important role in the yield decline of pyrethrum in Australia.
Efficient Two-Stage Analysis for Complex Trait Association with Arbitrary Depth Sequencing Data
Authors: Xu Zheng , Yan Song , Yuan Shuai , Wu Cong , Chen Sixia , Guo Zifang , Li Yun 
Published: March 2023

Sequencing-based genetic association analysis is typically performed by first generating genotype calls from sequence data and then performing association tests on the called genotypes. Standard approaches require accurate genotype calling (GC), which can be achieved either with high sequencing depth (typically available in a small number of individuals) or via computationally intensive multi-sample linkage disequilibrium (LD)-aware methods. We propose a computationally efficient two-stage combination approach for association analysis, in which single-nucleotide polymorphisms (SNPs) are screened in the first stage via a rapid maximum likelihood (ML)-based method on sequence data directly (without first calling genotypes), and then the selected SNPs are evaluated in the second stage by performing association tests on genotypes from multi-sample LD-aware calling. Extensive simulation- and real data-based studies show that the proposed two-stage approaches can save 80% of the computational costs and still obtain more than 90% of the power of the classical method to genotype all markers at various depths d≥2.
KAN DENİZİNE YUKARIDAN BAKMAK: 25 NİSAN ÇIKARTMASINDA İTİLAF HAVA GÜCÜ FAALİYETLERİ
Authors: KURT Emin 
Published: March 2023

Çanakkale Savaşı, Türk tarih incelemelerinde olduğu kadar dünya askeri tarih incelemelerinde en çok araştırma yapılan savaşlardan birisidir. Savaşın hemen hemen her boyutu ayrı ayı incelendi. Çanakkale Savaşı’na duyulan bu ilgi ve geniş literatürün aksine incelenmeyeni gözlerden uzak kalan konu savaşın havacılık boyutu oldu. Çanakkale Savaşı hava faaliyetlerini incelen çalışmalar bir elin parmaklarını geçmedi ve ne yazık ki konuya Türk perspektif ve Türk kaynaklarından bakmaktan ileriye gidemedi.
Bilinenin aksime Çanakkale Savaşı yoğun bir hava harekâtına sahne oldu. Türk havacılarının Birinci Dünya Savaşı sırasında görev aldığı ilk cephe Çanakkale Cephesi olurken, ilk operatif hava birliği olan 1. Tayyare Bölüğü, Çanakkale Cephesi’nde kuruldu. İtilaf Devletleri de Çanakkale’de büyük denebilecek bir hava gücü bulundurdu.
18 Mart 1915’de İtilaf Donanmasının Çanakkale Boğazı’nı geçmemesi üzerine, çatışmalar müşterek bir harekâta evrilirken, bölgedeki İtilaf hava güce de sayı olarak arttırıldı. Harp sahasına gelen ilk İtilaf hava gücünü barındıran Ark Royal uçak gemisine uçak takviyesi yapılırken, İngiliz Donanma Hava Servisine bağlı 3. Filo’da gölgede konuşlandırıldı. Bu hava gücü daha sonra Fransız deniz uçakları ile takviye edildi.
İngiliz havacılar 25 Nisan 1915 çıkartmasında kan denizinin üzerinde uçtuklarını ifade ettiler. Yüksekten ve geniş bakış açısından yaşanan kıyafetin canlı tanıkları oldular. Bu çalışmada 25 Nisan çıkartması öncesinde İtilaf hava gücünün arttırılmasına yönelik çalışmalara ve çıkartma günü İtilaf hava gücünün faaliyetlerine odaklanacaktır. Konu İngiliz ve Türk arşiv kaynakları ve dönemin şahitlerinin anıları ile karşılaştırmalı incelenerek, İtilaf hava gücünün çıkartma anındaki etkinliği ortaya konulmaya çalışılacaktır.
Modified method of TMJ arthrocentesis with synchronous feeding with two needles under ultrasound control
Authors: Bekreev V.V. , Sarkisyan M.S. , Kazarian G.G. 
Published: March 2023

The aim of the study was to develop and apply a modified technique of 2-puncture arthrocentesis of the upper TMJ joint space with simultaneous supply of saline solution for the treatment of patients with anterior disc displacement.
Based on literature data and our own research, a modified method of TMJ arthrocentesis with synchronous solution feeding by two needles under ultrasound control under local anesthesia was proposed. The application of the proposed method for the treatment of a 31-year-old patient with internal TMJ disorders with complaints of clicks and periodic pain in the right TMJ area is described.
The use of a modified arthrocentesis technique showed an increase in the maximum mouth opening immediately after the procedure by 0.2 cm (from 4.2 to 4.4 cm) and a decrease in clicks in the right TMJ during mandibular movements. The time spent on the procedure was less than 2 minutes, while saline was injected in a volume of up to 2 mlt is concluded that the modifie
d method of TMJ arthrocentesis with synchronous injection of the solution with two needles is effective and promising, allowing to reduce the volume of the solution and the time spent on the procedure compared with the classical methods of arthrocentesis and arthroplavage, and the ultrasound guidance used allows you to control the correct position of the needles and the distribution of the wound in the joint gap. At the same time, further clinical studies with control groups and a larger sample of patients are needed for wider application of the method.
Keywords: arthrocentesis, temporomandibular joint, ultrasound.
A study on correction method of total acoustic power in presence of shielding in focused ultrasound treatment using acoustic radiation force imaging
Authors: Numahata Erika , Yoshizawa Shin , Umemura Shin-ichiro , Ishii Takuro , Saijo Yoshifumi 
Published: March 2023

Abstract
High-intensity focused ultrasound (HIFU) therapy is a noninvasive treatment for cancer. Prediction of the HIFU treatment region in advance by ultrasound imaging is important for the efficacy and safety of the treatment. Acoustic radiation force (ARF) imaging has been shown to be useful in estimating the heat distribution caused by HIFU. In this study, we investigated the effect of shielding on the estimated heat distribution when the propagation of HIFU is partially shielded by an object simulating ribs, imitating an actual clinical situation, and examined the correction method of HIFU output power using ARF imaging to obtain tissue coagulation equivalent to that without shielding. As a result, it was suggested that even with partial acoustic shielding, when the HIFU output power is adjusted so that the displacement induced by ARF is equal to that without shielding, almost the same coagulated region can be obtained as in the unshielded case.
Strategi Pengembangan Objek Wisata Ollon di Kabupaten Tana Toraja
Authors: Juliansi Sry , Manaf Murshal , Jufriadi Jufriadi 
Published: March 2023

Abstract.This study aimed to analyze what factors cause the Ollon Tourism Object to not develop and to identify the strategy for developing Ollon Tourism Object. This research approach uses qualitative and quantitative approaches by collecting quantitative data which then uses Multiple Linear Regression analysis to measure what factors and how much influence the development of tourist objects then uses the SWOT analysis tool to identify strategies for developing tourist objects. The conclusion from this study is that there are two factors that have caused the Ollon Tourism Object in Lembang Bau, Bonggakaradeng District to not develop, including factors from infrastructure (telecommunication network conditions, electricity networks, garbage/waste networks, transportation networks) and accessibility (road network conditions). The conclusion from the results of the SWOT analysis to identify the strategy for developing the Ollon Tourism Object is in quadrant I between the SO strategy (strength-opportunity) by using all the strengths it has to take advantage of all the opportunities as much as possible.
Abstrak. Tujuan dari penelitian ini ialah untuk menganalisis faktor-faktor apa yang menyebabkan sehingga Objek Wisata Ollon belum berkembang dan mengidentifikasi strategi pengembangan Objek Wisata Ollon. Pendekatan penelitian ini menggunakan pendekatan kualitatif dan kuantitatif dengan cara mengumpulkan data kuantitatif yang kemudian menggunakan analisis Regresi Linear Berganda untuk mengukur faktor apa dan seberapa besar pengaruh perkembangan objek wisata yang kemudian menggunakan alat analisis SWOT untuk mengidentifikasi strategi pengembangan objek wisata. Kesimpulan dari penelitian ini ialah terdapat dua faktor yang menyebabkan sehingga Objek Wisata Ollon di Lembang Bau, Kecamatan Bonggakaradeng belum berkembang, diantaranya yaitu faktor dari prasarana (kondisi jaringan telekomunikasi, jaringan listrik, jaringan persampahan/limbah, jaringan transportasi) dan aksesibilitas (kondisi jaringan jalan). Kesimpulan dari hasil analisis SWOT untuk mengidentifikasi strategi pengembangan Objek Wisata Ollon yaitu berada pada kuadran I diantara strategi SO (strength-opportunity) dengan menggunakan seluruh kekuatan yang dimiliki untuk memanfaatkan seluruh peluang sebesar-besarnya.
ANALISIS DAMPAK KEBIJAKAN MERDEKA BELAJAR - KAMPUS MERDEKA TERHADAP MAHASISWA PROGRAM STUDI AKUNTANSI UNIVERSITAS SAHID
Authors: MY Ani Siska , Anggraini Dewi 
Published: March 2023

Merdeka Belajar - Kampus Merdeka (MBKM) merupakan kebijakan yang sejalan dengan Peraturan Menteri Pendidikan dan Kebudayaan (Permendikbud) No. 3 Tahun 2020 tentang Standar Nasional Pendidikan Tinggi. Tujuan MBKM untuk menyiapkan generasi yang mampu menjawab tantangan dan permintaan pasar atas tenaga kerja dalam dunia usaha dan industri. Penelitian ini adalah penelitian deskriptif dengan menggunakan mix-method dengan menggabungkan metode kualitatif dan kuantitatif. Untuk memperoleh informasi dengan menyebarkan kuesioner kepada 314 mahasiswa prodi akuntansi semester ganjil 2021/2022, studi kepustakaan, dan focus group discussion (FGD). Hasil penelitian menunjukkan mahasiswa menyambut baik kebijakan MBKM. Program Studi Akuntansi Univeritas Sahid telah menyusun kurikulum sesuai dengan Permendikbud No. 3 Tahun 2020 Pasal 18. Pada semester ganjil tahun akademik 2021/2022 telah dilakukan kegiatan pembelajaran MBKM yaitu pertukaran pelajar.