bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inflammatory mechanisms and intervention strategies for sepsis‐induced myocardial dysfunction
Authors: Nong Yuxin , Wei Xuebiao , Yu Danqing 
Published: May 2023

AbstractSepsis‐induced myocardial dysfunction (SIMD) is the leading cause of death in patients with sepsis in the intensive care units. The main manifestations of SIMD are systolic and diastolic dysfunctions of the myocardium. Despite our initial understanding of the SIMD over the past three decades, the incidence and mortality of SIMD remain high. This may be attributed to the large degree of heterogeneity among the initiating factors, disease processes, and host states involved in SIMD. Previously, organ dysfunction caused by sepsis was thought to be an impairment brought about by an excessive inflammatory response. However, many recent studies have shown that SIMD is a consequence of a combination of factors shaped by the inflammatory responses between the pathogen and the host. In this article, we review the mechanisms of the inflammatory responses and potential novel therapeutic strategies in SIMD.
SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19
Authors: Al‐kuraishy Hayder M. , Hussien Nawar R. , Al‐Niemi Marwa S. , Fahad Esraa H. , Al‐Buhadily Ali K. , Al‐Gareeb Ali I. , Al‐Hamash Sadiq M. , Tsagkaris Christos , Papadakis Marios , Alexiou Athanasios , Batiha Gaber El‐Saber 
Published: May 2023

AbstractIntroductionCovid‐19 is linked with the development of cardio‐metabolic disorders, including dyslipidemia, dysregulation of high‐density lipoprotein (HDL), and low‐density lipoprotein (LDL). Furthermore, SARS‐Co‐2 infection is associated with noteworthy changes in lipid profile, which is suggested as a possible biomarker to support the diagnosis and management of Covid‐19.MethodsThis paper adopts the literature review method to obtain information about how Covid‐19 affects high‐risk group patients and may cause severe and critical effects due to the development of acute lung injury and acute respiratory distress syndrome. A narrative and comprehensive review is presented.ResultsReducing HDL in Covid‐19 is connected to the disease severity and poor clinical outcomes, suggesting that high HDL serum levels could benefit Covid‐19. SARS‐CoV‐2 binds HDL, and this complex is attached to the co‐localized receptors, facilitating viral entry. Therefore, SARS‐CoV‐2 infection may induce the development of dysfunctional HDL through different mechanisms, including induction of inflammatory and oxidative stress with activation of inflammatory signaling pathways. In turn, the induction of dysfunctional HDL induces the activation of inflammatory signaling pathways and oxidative stress, increasing Covid‐19 severity.ConclusionsCovid‐19 is linked with the development of cardio‐metabolic disorders, including dyslipidemia in general and dysregulation of high‐density lipoprotein and low‐density lipoprotein. Therefore, the present study aimed to overview the causal relationship between dysfunctional high‐density lipoprotein and Covid‐19.
COVID‐19 as a trigger of Guillain‐Barré syndrome: A review of the molecular mechanism
Authors: Malekpour Mahdi , Khanmohammadi Shaghayegh , Meybodi Mohammad Javad Entezari , Shekouh Dorsa , Rahmanian Mohammad Reza , Kardeh Sina , Azarpira Negar 
Published: May 2023

AbstractSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) caused a pandemic with serious complications. After coronavirus disease 2019 (COVID‐19), several post‐acute COVID‐19 syndromes (PACSs) and long‐COVID sequels were reported. PACSs involve many organs, including the nervous, gustatory, and immune systems. One of the PACSs after SARS‐CoV‐2 infection and vaccination is Guillain‐Barré syndrome (GBS). The incidence rate of GBS after SARS‐CoV‐2 infection or vaccination is low. However, the high prevalence of COVID‐19 and severe complications of GBS, for example, autonomic dysfunction and respiratory failure, highlight the importance of post‐COVID‐19 GBS. It is while patients with simultaneous COVID‐19 and GBS seem to have higher admission rates to the intensive care unit, and demyelination is more aggressive in post‐COVID‐19 GBS patients. SARS‐CoV‐2 can trigger GBS via several pathways like direct neurotropism and neurovirulence, microvascular dysfunction and oxidative stress, immune system disruption, molecular mimicry, and autoantibody production. Although there are few molecular studies on the molecular and cellular mechanisms of GBS occurrence after SARS‐CoV‐2 infection and vaccination, we aimed to discuss the possible pathomechanism of post‐COVID‐19 GBS by gathering the most recent molecular evidence.
Examining characteristics and experiences of Black firearm owners
Authors: Bond Allison E. , Brooks Jasmin R. , Rodriguez Taylor R. , Bandel Shelby L. , Anestis Michael D. 
Published: May 2023

AbstractObjectiveThe present study sought to better understand the characteristics of those who own firearms in the Black community; and to understand how Black firearm owners differ from nonfirearm owning Black individuals on a variety of variables related to safety, threat concerns, and suicide risk.MethodsTwo samples were utilized in this study. The first was a subsample of those who identified as Black from a nationally representative sample (N = 502) seeking to understand firearm ownership within the United States. The second used a subsample of those who identified as Black (N = 1086) from a representative sample from New Jersey, Minnesota, and Mississippi. Variables related to safety and threat concerns were included in the second sample.ResultsIn both samples, multiple demographic variables, such as being a woman and having higher education, predicted firearm ownership. In the second sample, experiences of everyday discrimination and crime experiences were associated with firearm ownership. Additionally, Black firearm owners reported significantly more suicidal ideation than Black nonfirearm owners.ConclusionThe findings demonstrate the unique characteristics and experiences of Black firearm owners and show that firearm ownership is associated with increased suicide risk factors for Black adults. Findings should be used to advocate for the creation of more culturally relevant suicide prevention and firearm means safety strategies.
Reflections on authenticity, action, and leadership
Authors: Gardiner Rita A. 
Published: May 2023

SummaryThis paper is a reflection on an article by Hellmuth et al., and is part of the point‐counterpart series. In this reflection, I consider the etymological origins of the term “authenticity” and explore the existential and phenomenological aspects of authenticity, action, and leadership. In particular, I note the absence of contextual issues such as gender.
Increasing heatwave with associated population and GDP exposure in North China
Authors: Zhang Guwei , Ma Jiali , Meng Chunchun , Wang Jie , Xu Zhiqi , Gou Peng 
Published: May 2023

AbstractTwenty‐seven CMIP6 models were grouped into three ensembles based on the simulated performance of heatwaves in North China during present‐day (1995–2014), and future changes in the duration and intensity of heatwaves were projected under SSP1‐2.6, SSP2‐4.5 and SSP5‐8.5. The selected three ensembles showed consistent projections: both the duration and intensity of heatwaves would increase significantly, with the greatest under SSP5‐8.5. Besides, the heatwave growth in 2081–2100 would double in 2041–2060, except for SSP1‐2.6, where heatwaves would be similar in both periods. For the spatial distribution, the duration (intensity) would increase more in southern (western) parts of North China. Combining heatwaves with population and GDP, future heat exposures would concentrate on urban areas and the tertiary industry. For example, the 2041–2060 population exposure would reach 3.2–5.6 times the current level, with contributions from the urban population ranging from 55% to 60%. The GDP exposure would hit tens to hundreds of times the current level, with the tertiary sector replacing the secondary sector as the leading industry in North China, producing the major contribution and facing significant heat‐related risks. Overall, there will be significant heat‐related impacts under SSP5‐8.5, about 1.5–3.0 fold of those under SSP1‐2.6 and SSP2‐4.5. The urban and tertiary sectors would suffer greater risks relative to the rural and other industries. Our results reinforced the need to minimize global emissions and develop strategic plans to mitigate heat impacts under high‐emission scenarios, especially for urban areas and the tertiary industry, requiring great attention to climate adaptation.
Effect of scaling and root planing with and without minocycline HCl microspheres on periodontal pathogens and clinical outcomes: A randomized clinical trial
Authors: Arnett Michelle C. , Chanthavisouk Phonsuda , Costalonga Massimo , Blue Christine M. , Evans Michael D. , Paulson Danna R. 
Published: May 2023

AbstractBackgroundThis study tests the effects of scaling and root planing (SRP) versus SRP plus minocycline hydrochloride microspheres (SRP+MM) on 11 periodontal pathogens and clinical outcomes in Stage II‐IV Grade B periodontitis participants.MethodsSeventy participants were randomized to receive SRP (n = 35) or SRP+MM (n = 35). Saliva and clinical outcomes were collected for both groups at baseline before SRP, 1‐month reevaluation, and at 3‐ and 6‐month periodontal recall. MM were delivered to pockets ≥5 mm immediately after SRP and immediately after the 3‐month periodontal maintenance in the SRP+MM group. A proprietary saliva test* was utilized to quantitate 11 putative periodontal pathogens. Microorganisms and clinical outcomes were compared between groups using generalized linear mixed‐effects models with fixed effects and random effects terms. Mean changes from baseline were compared between groups via group‐by‐visit interaction tests.ResultsSignificant reduction in Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, Prevotella intermedia, Parvimonas micra, and Eikenella corrodens were identified at the 1‐month reevaluation after SRP+MM. Six months after SRP with a re‐application of MM 3 months after SRP, Fusobacterium nucleatum, Prevotella intermedia, Campylobacter rectus, and Eikenella corrodens were significantly reduced. SRP+MM participants had significant clinical outcome reductions in pockets ≥5 mm at the reevaluation, 3‐ and 6‐month periodontal maintenance, and clinical attachment loss gains at the 6‐month periodontal maintenance.ConclusionMM delivered immediately after SRP and reapplication at 3 months appeared to contribute to improved clinical outcomes and sustained decreased numbers of Fusobacterium nucleatum, Prevotella intermedia, Campylobacter rectus, and Eikenella corrodens at 6 months.
Long‐term Outcomes Following Endoscopic Transnasal Surgery for Optic Neuropathy Due to Craniofacial Fibrous Dysplasia
Authors: Wang Min , Zhu Senmiao , Shen Bingyan , Fang Yenan , Xie Qiqi , Dai Qin , Chen Ziwen , Li Xinyu , Wu Wencan 
Published: May 2023

ObjectiveTo investigate the feasibility of endoscopic transnasal optic canal decompression (ETOCD) guided by a navigation surgical system (NSS) for vision recovery in patients with compressive optic neuropathy (CON) caused by craniofacial fibrous dysplasia (CFD), and to explore the underlying cause of visual impairment.MethodsAll patients underwent unilateral NSS‐guided ETOCD and were followed up periodically for at least six months. Paired sample t‐test and Pearson correlation analyses were used to compare continuous variables of the visual outcomes at the final review. A histopathological test of abnormal bone specimens was performed postoperatively.ResultsThirty‐four patients were finally included, and all surgeries were uneventful. The best corrected visual acuity (BCVA) (logMAR units) decreased from 1.29 ± 0.80 preoperatively to 0.97 ± 0.78 at the last follow‐up (p = 0.0012), improving in 28 patients (82.35%). The absolute value of mean defect (MD) significantly decreased (p < 0.001). Color vision was impaired in 17 patients preoperatively and improved in 6 patients. BCVA at the last follow‐up was significantly correlated with preoperative BCVA, onset time, preoperative retinal nerve fibril layer thickness, and MD (all p < 0.05). Among 34 patients, 26 had a blunt bony process near the anterior foot of the optic chiasm. Of the total patients, 73.53% patients experienced bony fiber recurrence 6 months or earlier after surgery without visual loss.ConclusionNSS‐guided ETOCD appeared to be safe and effective for visual recovery in patients with CON due to CFD, and early surgical intervention was critical for long‐term recovery. Unbalanced compression of the optic canal by the blunt bony process may be a major cause of visual impairment.Level of Evidence4 Laryngoscope, 133:1857–1866, 2023
Ordinary customer experience: Conceptualization, characterization, and implications
Authors: Heinonen Kristina , Lipkin Michaela 
Published: May 2023

AbstractAlthough businesses strive to create extraordinary customer experiences, it is the ordinary experiences that form the backbone of customers' lives and hold the greatest potential for creating meaning and relevance. This conceptual study aims to shed light on the sources, characteristics, and mechanisms of the ordinary customer experience by conducting a scoping review of literature from various fields, including sociology, philosophy, consumer behavior, psychology, marketing, and management. The findings demonstrate that researchers characterize the ordinary customer experience as familiar, simple, and mundane—and thus often taken for granted—and as formed through customers' daily routines. This study defines the ordinary experience as the accumulation of a customer's perceptions, feelings, and sensemaking of customer‐specific, contextual, and offering‐related stimuli that are meaningfully and purposefully present in the customer's daily life. The ordinary experience representing a lived and reflective phenomenon is characterized as peripheral, predictable, neutral, acceptable, longitudinal, and convenient. Despite its seemingly mundane nature, the ordinary customer experience provides valuable insights into customers' sensemaking of experiences. By reconciling and bridging understandings from various fields, this study presents a comprehensive view of the ordinary customer experience and contributes to a more granular and holistic understanding of the ordinary in the marketing domain. It offers an alternative perspective on customer experience that extends beyond the conventional ordinary–extraordinary continuum.
PET‐RAFT Polymerization of Star Polymers with Folded ortho‐Phenylene Cores
Authors: Bradford Kate G. E. , Kirinda Viraj C. , Gordon Emma A. , Hartley C. Scott , Konkolewicz Dominik 
Published: May 2023

Abstractortho‐Phenylenes are one of the simplest classes of aromatic foldamers, adopting helical geometries because of aromatic stacking interactions. The folding and misfolding of ortho‐phenylenes are slow on the NMR timescale at or below room temperature, allowing detection of folding states using 1H NMR spectroscopy. Herein, an ortho‐phenylene hexamer is coupled with a RAFT chain transfer agent (CTA) on each repeat unit. A variety of acrylic monomers are polymerized onto the CTA‐functionalized ortho‐phenylene using PET‐RAFT to yield functionalized star polymers with ortho‐phenylene cores. The steric bulk of the acrylate monomer units as well as the chain length of each arm of the star polymer is varied. 1H NMR spectroscopy shows that the folding of the ortho‐phenylenes do not vary, providing a robust helical core for star polymer systems.
Achieving High Performance Stretchable Conjugated Polymers via Donor Structure Engineering
Authors: Wu Ning , Huang Gang , Huang Hua , Wang Yunfei , Gu Xiaodan , Wang Xiaohong , Qiu Longzhen 
Published: May 2023

AbstractA backbone engineering strategy is developed to tune the mechanical and electrical properties of conjugated polymer semiconductors. Four Donor–Acceptor (D–A) polymers, named PTDPPSe, PTDPPTT, PTDPPBT, and PTDPPTVT, are synthesized using selenophene (Se), thienothiophene (TT), bithiophene (BT), and thienylenevinylenethiophene (TVT) as the donors and siloxane side chain modified diketopyrrolopyrrole (DPP) as acceptor. The influences of the donor structure on the polymer energy level, film morphology, molecular stacking, carrier transport properties, and tensile properties are all examined. The films of PTDPPSe show the best stretchability with crack‐onset‐strain greater than 100%, but the worst electrical properties with a mobility of only 0.54 cm2 V−1 s−1. The replacement of the Se donor with larger conjugated donors, that is, TT, BT, and TVT, significantly improves the mobility of conjugated polymers but also leads to reduced stretchability. Remarkably, PTDPPBT exhibits moderate stretchability with crack‐onset‐strain ≈50% and excellent electrical properties. At 50% strain, it has a mobility of 2.37 cm2 V−1 s−1 parallel to the stretched direction, which is higher than the mobility of most stretchable conjugated polymers in this stretching state.
A social capital approach of market orientation in public non‐profit organizations: The case of blood transfusion centers in Spain
Authors: de la Cruz Déniz‐Déniz María , Martín‐Santana Josefa D. , Cabrera‐Suárez María Katiuska , Robaina‐Calderín Lorena 
Published: May 2023

AbstractIn order to identify the determinants of market (donor) orientation in blood transfusion centers and services (BTCS), this study seeks to analyze whether connectedness and interpersonal trust represent a fundamental basis for interfunctional coordination that leads to market (donor) orientation. An empirical study was carried out with 147 participants from 14 Spanish BTCS. The measurement scales were validated through CFA and the proposed relationship model was tested using SEM. Both interpersonal trust and connectedness that exist among BTCS members foster interfunctional coordination and, ultimately, their donor orientation. Thus, BTCS must emphasize their internal relationship networks, rearranging them in favor of their donor orientation. This paper integrates social capital literature with market orientation literature, and it proposes empirical evidence on the role played by internal social links on interfunctional coordination, which leads to market orientation. This research proposes a reliable and valid measure of blood donor orientation, which could be useful for the future testing of theory and research in the non‐profit context. BTCS should adopt an organizational design which allows the introduction of a new managerial paradigm. People in charge of different areas at BTCS must pay particular attention to the climate of trust and the level of connectedness in cross‐functional relationships. The negative evolution of blood donation and the results of this research suggest that BTCS need to apply a management model focused on the donor, in order to achieve a sustainable donation system.
Experimental characterization of creep behavior of laminated bamboo composites based on stepped isothermal method
Authors: Liu Yanyan , Huang Zirui , Sheng Baolu , Wang Wendao , Zhang Kun 
Published: May 2023

AbstractIn the present research, the accelerated test using the stepped isothermal method (SIM) was applied to characterize the long‐term compressive behavior of laminated bamboo. Generating a creep master curve using the SIM data is somewhat empirical. In particular, the selection of the end and beginning segments in the rescaling process is not standardized, which will affect the determination of virtual time. The variability of the virtual time influences the construction of master curves, thus leading to errors in predicting long‐term behavior. The difference in selecting the end and beginning segments was studied in terms of the virtual time, rescaled isothermal curves, and master curves. A 40% end segment and a 30% beginning segment were recommended to build a more accurate master curve. The generated master curves showed repeatability and matched reasonably well with the conventional creep results. It indicates that SIM is a reliable tool for the accelerated test of the long‐term behavior of laminated bamboo. In addition, isochronous stress‐creep strain curves were constructed based on the master curves at different loadings to provide evidence to determine stress levels for structural design.
Quality evaluation of different black rice varieties of northeastern region of India
Authors: Banerjee Rupesh , Das Gupta Barun , Kar Amit , Bhardwaj Pardeep Kumar , Sharma Nanaocha , Haldar Pallab Kanti , Bandyopadhyay Rajib , Mukherjee Pulok Kumar 
Published: May 2023

AbstractIntroductionBlack rice (Oryza sativa L.), which is rich in polyphenols and flavonoids, is indigenous to Northeast India, specifically Manipur, and traditionally consumed for its protective effects on human health. Due to its economic value, it is crucial to evaluate the quality of different black rice varieties to authenticate their therapeutic and nutritional properties.ObjectiveWe aimed to evaluate the quality of pre‐ and post‐marketed black rice samples by a validated high‐performance thin layer chromatography method and determine variations of total phenolics and total flavonoids with antioxidant potential.Material and MethodsThe ferulic acid, gallic acid, quercetin, and caffeic acid contents of three black rice varieties—Poireiton, Amubi, and Sempak—along with two marketed samples of Amubi from Manipur, India, were quantified based on standards. Antioxidant potential was measured by the 2,2‐diphenyl‐1‐picryl‐hydrazyl hydrate free radical scavenging assay.ResultsThe highest and lowest relative biomarker contents were found in hydroalcoholic extracts of Amubi [caffeic acid (1.43% w/w), ferulic acid (1.15% w/w), quercetin (0.6% w/w), and gallic acid (0.39% w/w)] and the marketed sample Var. Amubi from Kakching District, respectively. Pearson's correlation coefficient of antioxidant potential with phenolic and flavonoid content showed a moderate to strong correlation for all samples.ConclusionThis validated, rapid, accurate standardization method for black rice varieties will be beneficial for the quality evaluation of black rice and its derived products. It will also be helpful to authenticate the nutritional benefits for the consumers.
Effects of 12 minutes aerobic exercise on creativity
Authors: Zhao Yuan , Qin Chuan , Liu Dianzhi 
Published: May 2023

AbstractThe purpose of this study was to explore the effects of 12 min of aerobic exercise on the convergent and divergent thinking of college students. In 56 college students, aerobic exercise promoted convergent thinking when participating in infrequent exercises. Aerobic exercise also improved fluency in divergent thinking.