bluuebunny/crossref_metadata_2025_split huggingface dataset:
FOSSIL. III. Lightcurves of 371 Trans-Neptunian Objects
Authors: Ashton Edward , Chang 章 Chan-Kao 展誥 , Chen 陳 Ying-Tung 英同 , Lehner Matthew J. , Wang 王 Shiang-Yu 祥宇 , Alexandersen Mike , Choi 최 Young-Jun 영준 , Fraser Wesley C. , Granados Contreras A. Paula , Ito 伊藤 Takashi 孝士 , JeongAhn 정안 Youngmin 영민 , Ji 季 Jianghui 江徽 , Kavelaars JJ , Kim 김 Myung-Jin 명진 , Lawler Samantha M. , Li 黎 Jian 健 , Lin 林 Zhong-Yi 忠義 , Lykawka Patryk Sofia , Moon 문 Hong-Kyu 홍규 , More Surhud , Muñoz-Gutiérrez Marco A. , Ohtsuki 大槻 Keiji 圭史 , Pike Rosemary E. , Terai Tsuyoshi , Urakawa 浦川 Seitaro 聖太郎 , Yoshida 吉田 Fumi 二美 , Zhang Hui , Zhao 赵 Haibin 海斌 , Zhou 周 Ji-Lin 济林 ,   (The FOSSIL Collaboration)
Published: July 2023

Abstract
From the first phase of the high-cadence Formation of the Outer Solar System: an Icy Legacy (FOSSIL) survey, we analyzed lightcurves, ranging from one to four nights in length, of 371 trans-Neptunian objects (TNOs) for periodicity. We found 29 TNOs with periodic lightcurves, one of which is a good candidate for a close/contact binary. Another of the periodic FOSSIL TNOs could potentially have the fastest of all known TNO spin rates, with a period of 1.3 hr. We do not have total confidence in the period and thus plan to obtain a more detailed lightcurve for confirmation. The periodic TNOs have an average rotation period of 11.2 hr, close to the value obtained by Alexandersen et al., which had similar cadence, but different from other surveys. In regards to contention in the literature about whether smaller TNOs are more irregular in shape and thus have larger lightcurve amplitudes, we found that there is a weak correlation between absolute magnitude and lightcurve amplitude in a subset of 194 FOSSIL TNOs, even when using the more appropriate brightest (minimum) absolute magnitude instead of the time-averaged value.
A Data Science Platform to Enable Time-domain Astronomy
Authors: Coughlin Michael W. , Bloom Joshua S. , Nir Guy , Antier Sarah , du Laz Theophile Jegou , van der Walt Stéfan , Crellin-Quick Arien , Culino Thomas , Duev Dmitry A. , Goldstein Daniel A. , Healy Brian F. , Karambelkar Viraj , Lilleboe Jada , Shin Kyung Min , Singer Leo P. , Ahumada Tomás , Anand Shreya , Bellm Eric C. , Dekany Richard , Graham Matthew J. , Kasliwal Mansi M. , Kostadinova Ivona , Kiendrebeogo R. Weizmann , Kulkarni Shrinivas R. , Jenkins Sydney , LeBaron Natalie , Mahabal Ashish A. , Neill James D. , Parazin B. , Peloton Julien , Perley Daniel A. , Riddle Reed , Rusholme Ben , van Santen Jakob , Sollerman Jesper , Stein Robert , Turpin D. , Wold Avery , Amat Carla , Bonnefon Adrien , Bonnefoy Adrien , Flament Manon , Kerkow Frank , Kishore Sulekha , Jani Shloke , Mahanty Stephen K. , Liu Céline , Llinares Laura , Makarison Jolyane , Olliéric Alix , Perez Inès , Pont Lydie , Sharma Vyom 
Published: July 2023

Abstract

SkyPortal is an open-source software package designed to discover interesting transients efficiently, manage follow-up, perform characterization, and visualize the results. By enabling fast access to archival and catalog data, crossmatching heterogeneous data streams, and the triggering and monitoring of on-demand observations for further characterization, a SkyPortal-based platform has been operating at scale for >2 yr for the Zwicky Transient Facility Phase II community, with hundreds of users, containing tens of millions of time-domain sources, interacting with dozens of telescopes, and enabling community reporting. While SkyPortal emphasizes rich user experiences across common front-end workflows, recognizing that scientific inquiry is increasingly performed programmatically, SkyPortal also surfaces an extensive and well-documented application programming interface system. From back-end and front-end software to data science analysis tools and visualization frameworks, the SkyPortal design emphasizes the reuse and leveraging of best-in-class approaches, with a strong extensibility ethos. For instance, SkyPortal now leverages ChatGPT large language models to generate and surface source-level human-readable summaries automatically. With the imminent restart of the next generation of gravitational-wave detectors, SkyPortal now also includes dedicated multimessenger features addressing the requirements of rapid multimessenger follow-up: multitelescope management, team/group organizing interfaces, and crossmatching of multimessenger data streams with time-domain optical surveys, with interfaces sufficiently intuitive for newcomers to the field. This paper focuses on the detailed implementations, capabilities, and early science results that establish SkyPortal as a community software package ready to take on the data science challenges and opportunities presented by this next chapter in the multimessenger era.
Un nouveau document sur la légende d’Horus : le P. IFAO H 88 roوثيقة جديدة عن أسطورة حورس: اﻟ«P. IFAO H 88 ro»
Authors: Herbin François René 
Published: July 2023

Reconstitution partielle et analyse, à partir de quelques fragments hiératiques ramessides, d’un nouveau document sur la légende d’Horus agressé alors qu’il était enfant dans la région de Bouto par un serpent agissant comme substitut de Seth. Le cri d’Isis, sa réaction découvrant son enfant empoisonné, et les incantations qui suivent, adressées au serpent ou à son venin personnifié, sont connus par plusieurs sources qui offrent entre elles nombre de variantes. Des éléments de cette légende se lisent sur de rares documents tardifs connus depuis longtemps : la statue de Djed-Ḥer-le-Sauveur (Caire JE 46341), la base d’une statue similaire (le « socle Béhague », Leyde F 1950/8.2), toutes deux datables du début de l’époque ptolémaïque, et la stèle Metternich (MMA 50.85, règne de Nectanébo II). On en connaît aujourd’hui une version développée plus ancienne sur un papyrus hiératique du Nouvel Empire (P. BM EA 10309+9997). Le papyrus IFAO H 88 ro ici étudié est à ajouter à la liste. Contemporain du manuscrit du British Museum, et bien que lui-même très incomplet, il inclut deux fragments substantiels dont le texte n’était attesté jusqu’à présent que sur le seul P. Brooklyn 47.218.138, un rituel tardif mais antérieur à l’époque ptolémaïque traitant de protection contre les animaux venimeux.
The Effect of Lower Limb Position on Anterior Cruciate Ligament Reconstruction on Uncommon Complications after Surgery
Authors: Aslani Hamidreza , Bonakdar Sona , Amoozade Farzad , Gorji Mona , Gholami Amir H. , Tajic Katayoun , Gholipour Morteza 
Published: July 2023

Background:To reduce the complications of orthopedic surgery, the desire for less invasive procedures, such as, knee arthroscopy to repair the anterior cruciate ligament, has increased. There are, currently, two common positions for limbs that are used during surgery depending on the surgeon's experience. Therefore, our aim was to investigate the effect of limb position on complications after anterior cruciate ligament reconstruction surgery.Materials and Methods:From April 2016 to July 2020 at our orthopedic-sports trauma center, 688 patients between the ages of 18 and 50 with anterior cruciate ligament rupture underwent reconstruction surgery with a hamstring graft. Patients were divided into two groups in terms of limb position at the time of surgery. For three months, patients were evaluated for surgical complications, basic demographic information, and information during surgery.Results:There was no statistically significant difference between the two groups in terms of demographic information, side of injury, preparation time, tourniquet time, operation time, and duration of hospitalization. At quarterly follow-up, there was no significant difference between the two groups in terms of postoperative complications (P= 0.976).Conclusions:There is no difference between compartment syndrome and deep vein thrombosis in different situations, therefore, the surgeon should operate in any position he is skilled in. Also, surgeons should always pay special attention to these complications and provide necessary training to patients in order to prevent them.
Detection of Genes Related to Linezolid Resistance (poxtA, cfr, and optrA) in Clinical Isolates of Enterococcus spp. from Humans: A First Report from Iran
Authors: Torabi Majid , Faghri Jamshid , Poursina Farkhondeh 
Published: July 2023

Background:

Enterococci may develop resistance to linezolid through chromosomal mutations that involve specific linezolid resistance genes, such as cfr, optrA, and poxtA. The objective of this study was to evaluate the antibiotic susceptibility of enterococcal isolates and identify cfr, optrA, and poxtA genes in MDR isolates.

Materials and Methods:
Enterococcal isolates were collected from various clinical specimens at Al-Zahra, Amin, and Khorshid Hospitals in Isfahan. The Enterococcus isolates were identified as belonging to the E. faecalis and E. faecium species by using specific gene (D alanine D alanine ligase ddl) sets in PCR. To detect cfr, optrA, and poxtA genes among the species, a multiplex-PCR assay was performed.

Results:
Out of 175 isolates, E. faecalis predominated 129/175 (73.7%). Furthermore, the prevalence of vancomycin-resistant Enterococci (VRE) and linezolid-resistant Enterococci (LRE) was 29.7% and 4%, respectively. The overall prevalence of MDR was 91.1%, 68.9%, and 66.6% of E. faecium, E. faecalis, and other Enterococcus spp., respectively. Interestingly, the frequency of optrA (71.4%) in E. faecium and poxtA and crf (42.8%) in E. faecalis were detected among LRE species. A statistically significant relationship (P < 0.05) was found between the presence of the three genes and the occurrence of LRE.

Conclusion:
This is the first study to report the detection of linezolid resistance genes (cfr, optrA, and poxtA) in clinical Enterococcus spp. isolates from Iran, conducted at Isfahan University of Medical Sciences hospitals. The emergence of enterococcal strains that resist linezolid is concerning as it can lead to the spread of resistant strains among patients, resulting in treatment failure.
Expression of CD24 as Cancer Stem Cell Marker in the Diagnosis of Oral Squamous Cell Carcinoma – A Prospective Study
Authors: Muralidoss Hemavathy , Muthusekhar M.R. 
Published: July 2023

AbstractIntroduction:Oral squamous cell carcinoma (OSCC) is an aggressive and recurrent malignancy. Identification of unique and overexpressed cell surface antigens is important in the diagnosis and development of cancer vaccines and various therapies for OSCC. We have used real-time polymerase chain reaction (RT-PCR) for the expression of cell surface protein CD24 in both tissue samples and in blood samples to study the clinicopathological features as well as to determine the gene expression profile of CD24 in OSCC and explore its role as a potential target of clinical therapy.Materials and Methods:In this prospective study, the expression of CD24 was evaluated in 20 blood (3 ml) and tissue samples of OSCC specimens by quantitative RT-PCR. Student’st-test was used for statistical analysis. The significance level was considered <0.05.Results:CD24 was found to be upregulated amongst the cases for both the tissue and the blood. CD24 was statistically significant withP< 0.05. Fold change was calculated to assess the quantity of the difference in expression amongst cases when compared to controls. Results were supportive of CD24 being a reliable biomarker, hence blood samples can also be used in screening and diagnosis of OSCC.Discussion:CD24 expression is significantly upregulated in blood and tissue samples in OSCC. In addition, CD24 overexpression is highly associated with adverse prognostic parameters such as lymph node involvement, advanced clinical stages and worse overall survival. Our findings have important implications in future practice, overexpression of CD24 in OSCC was associated with poor prognosis correlating to the clinical findings, large-scale comprehensive studies are needed further to confirm our findings. In addition to histological features, CD24 can be used as marker for OSCC.
Evaluation of Salivary Interleukin-6 in Patients with Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorders, Chronic Periodontitis and in Healthy Controls - A Cross-Sectional Comparative Study
Authors: Rani N. Alice Josephine , Vardhan B. G. Harsha , Srinivasan Srividhya , Gopal Saraswathi K. 
Published: July 2023

Abstract

Introduction:
Oral squamous cell carcinoma (OSCC) accounts for 95% among all head and neck cancers. Literature reveals saliva as a predictive, diagnostic and prognostic tool in carcinoma, inflammatory and genetic disorders. Expression of salivary interleukin-6 (IL-6) has been reported in patients with OSCC and in oral potentially malignant disorders (OPMDs). This study aims at the following objectives: · To evaluate the changes in the salivary levels of IL-6 in healthy individuals and those with chronic periodontitis (CP), OPMD and OSCC. · To compare the estimated levels of salivary IL-6 individually in healthy individuals and those with CP, OPMD and OSCC. · To assess the estimated levels of salivary IL-6 individually within histopathologically differentiated OSCC. · To analyse salivary IL-6 as a reliable biomarker in the diagnosis of OSCC.

Materials and Methods:
Totally, 60 patients were divided into four groups consisting of 15 patients in each group. Salivary samples were collected by simple drooling method. The concentration of IL-6 is to be determined by using Quantitative sandwich ELISA technique. All analyses were carried out using Statistical Package for Social Sciences (SPSS).

Results:
The concentration values of IL-6 were found to be more in OSCC group in comparison with the other three groups and the concentration values of OPMD were found to be more than in the CP and control group and was statistically significant.

Discussion:
We attempted a study to evaluate the salivary IL-6 in patients with OSCC, OPMDs and CP in comparison with the healthy controls. We achieved a pragmatic result showed that salivary IL-6 can be a reliable biomarker in the detection of OSCC. Saliva, due its wide array of functional characteristics, is an upcoming diagnostic fluid in the field of medicine and salivary IL-6 can be one such biomarker in the diagnosis of OSCC.
Posterior segment indications of handheld spectral domain optical coherence tomography in pediatric age group in a tertiary eye center in Egypt
Authors: Shokier Gihan M. 
Published: July 2023

Objective
The aim of this study was to detect the posterior segment indications for the use of handheld optical coherence tomography in the pediatric age group.

Patients and methods
This was a retrospective observational study that included patients who were candidates for handheld spectral domain optical coherence tomography (HH-OCT) imaging for retinal or optic nerve (ON) diseases in Abo Elreesh hospital during the period from June 2018 to June 2022. The image, demographic, and clinical database of the included patients were reviewed. Data were tabulated using Microsoft Excel. Appropriate statistical methods were used to analyze and correlate the obtained data.

Results
A total of 189 patients were included in this study, comprising 109 (57.7%) male patients. The mean age was 7.2±3.9 (range: 0.2–16 years) years. Overall, 46 (24.3%) patients were less than 5 years of age (i.e. infants and preschool age). Patients who underwent HH-OCT scanning due to retinal causes (i.e. nystagmus, unexplained poor vision, uveitis, Coat's disease, trauma, and high myopia) were 130 (68.8%) patients, whereas 59 (31.2%) patients were indicated due to ON disease (i.e. primary congenital glaucoma and juvenile open angle glaucoma, optic disc hyperemia, swelling or pallor, and cases of large physiological cupping).

Conclusion
HH-OCT is a noninvasive feasible image modality for evaluation of retina and ON in infants and young children. The lack of a normative database for retinal nerve fiber layer thickness and ON head parameters in the pediatric age group in the device available in our service is considered a limitation in its use for proper evaluation of different pathologies involving the ON.
Autologous platelet rich plasma versus punctal plugs for treatment of moderate to severe dry eye disease
Authors: Enany Hesham A. , Salamah Moustafa , Dessouky Reem A.K. 
Published: July 2023

Aim
To compare the outcomes of autologous platelet rich plasma (PRP) eye drops and inferior silicone punctal plugs in the treatment of moderate to severe dry eye disease (DED).

Patients and methods
This retrospective non-randomized comparative study included 46 patients with bilateral moderate to severe DED during the period from May 2021 to June 2022. They were divided into two groups, Group I: patients treated with autologous PRP eyedrops and Group II: patients treated with an inferior silicone punctal plug. The mean values of ocular surface disease index (OSDI), Schirmer's test (ST), fluorescein break up time (FBUT), and corneal fluorescein staining (CFS) were calculated for each group at baseline and at 2 weeks, 1 month, and 3 months follow-up. Mean posttreatment values were compared with baseline in each group. Mean values at baseline and at each follow up visit were compared between the two groups. Any complications were recorded.

Results
Group I included 50 eyes of 25 patients while group II included 42 eyes of 21 patients. Both groups showed statistically significant improvement in all DED parameters posttreatment compared with baseline (P<0.05). There was no statistically significant difference between the two groups regarding DED parameters at baseline and each follow-up visit (P>0.05). Reported complications were spontaneous loss of the plug in 19 (45.2%) eyes and persistent epiphora in 2 (4.8%) eyes in group II. No complications were noted in group I. The difference in complication rates between the two groups was highly significant (P<0.001).

Conclusion
Both autologous PRP eyedrops and inferior silicone punctal plugs are effective in the treatment of moderate to severe DED. However, inferior silicone punctal plugs are associated with more complications.
Outcomes of air versus sulfur hexafluoride tamponade in primary rhegmatogenous retinal detachment in phakic eyes
Authors: Tabl Ahmed A. , Shaheen Mahrous H. , El Alim Mohamed Ahmed A. , Tabl Marwa A. 
Published: July 2023

Purpose
To evaluate the outcomes of using air versus sulfur hexafluoride (SF6) gas tamponade in management of primary rhegmatogenous retinal detachment (RRD).

Study design
Retrospective case-series comparative study.

Patients and methods
We collected data from 120 patients in three tertiary university hospitals, that were diagnosed as primary RRD due to upper retinal break in the period from January 2021 to November 2022 and had undergone 23-G lens-sparing pars-plana vitrectomy with either air tamponade (Air group) or SF6 gas tamponade (SF6 group) and were followed up for 6 months. We analyzed the final visual outcomes between both groups.

Results
The mean age of the studied patients was 51±13 years (Air group=60 eyes, SF6 group=60 eyes). The mean axial length in Air group was 26.59±1.84 mm, the mean axial length was 26.46±1.49 mm in SF6 group. Best-corrected visual acuity was improved in both groups at the sixth month. In Air group 18.33% had recurrent RRD, while 10% in SF6 group. No significant difference regarding metamorphopsia was reported. Higher rate for cataract progression was noted among SF6 group.

Conclusions
Both Air and SF6 gas showed favorable results regarding the final visual outcome. Air is a less expensive tamponade with less timing for postoperative-prone positioning. Cataract progression was higher among SF6 group, however, the incidence of recurrent RRD was lower among SF6 group. Missed break was the primary cause for failed retinal reattachment.
The midpoint transverse process to pleura (MTP) block for postoperative analgesia in patients undergoing modified radical mastectomy: A case series
Authors: Kumar Rakesh , Mohammed Sadik , Paliwal Bharat , Kamal Manoj , Chhabra Swati , Bhatia Pradeep , Syal Rashmi 
Published: July 2023

Abstract
Among the various regional anesthesia techniques used for postoperative analgesia in the modified radical mastectomy (MRM), thoracic paravertebral block (TPVB) is presently considered the technique of choice. Nevertheless, TPVB may lead to complications like inadvertent vascular puncture, hypotension, epidural or intrathecal spread, pleural puncture, or pneumothorax. Recently, a newer technique “midpoint transverse process to pleura” (MTP) block has been described in which the tip of the needle is placed at the midpoint between the transverse process and pleura. In this case series, we included ten patients of American Society of Anesthesiologist status I/II scheduled for MRM. Ultrasound-guided MTP block was performed and the catheter was inserted on the side of the surgery at the level of T4 level. The block was successful in the all patients as their median visual analogue score at rest and movement was 2 and 3, respectively, in first 24 h postoperatively. Only three patients required rescue analgesia in the first 24 h. No procedural-related complications were noticed in any patient. We concluded that MTP block provided effective perioperative analgesia with minimal rescue analgesia requirement and satisfactory safety profile.
PELATIHAN BAGI DISABILITAS DALAM PEMBUATAN FROZEN FOOD: PEMPEK GLUTEN FREE DAN SOSIS DI KOTA PALEMBANG
Authors: Austin Trecy , Lisdiana Lisdiana , Prihatini Lishapsari , Pusnita Indah 
Published: July 2023

Penyandang disabilitas bagian dari keberagaman, namun adanya permasalahan seperti kurangnya kemampuan dan masih ada nya diskriminasi di lingkungan masyarakat mengurangi potensi serta terbatasnya keterampilan dan kemandirian pemuda disabilitas. Materi yang disampaikan adalah makanan sehat dengan pengenalan pembuatan pempek gluten free dan sosis dari ayam organik yang dikemas menjadi frozen food. Terdapat beberapa kendala yang dihadapi oleh pemuda disabilitas dalam pengembangannya yaitu, pengenalan bahan makanan yang tidak baik dikonsumsi secara berlebihan bagi disabilitas mental, dan masih belum mampu nya pendamping atau orangtua dalam memberikan asupan bergizi. Tujuan pengabdian ini, [1] Meningkatkan kapasitas pemuda disabilitas untuk berpartisipasi melalui pendidikan dan pelatihan, [2] Mengembangkan inovasi dan menjalankan teknologi, [3] Mengoptimalkan sumber daya yang tersedia, dan [4] Meningkatkan perekonomian dan kewirausahaan mandiri. Sehingga tim pengabdi memberikan pelatihan pembuatan pempek gluten free dan sosis dari ayam organik. Metode yang diterapkan dalam pengabdian ini, [1] Memberikan edukasi atau penyuluhan, [2] Praktik langsung memasak pempek gluten free dan sosis serta pengemasan menjadi makanan frozen food [3] Monitoring perkembangan pembuatan dan juga penjualan produk. Hasil kegiatan, meningkatnya partisipasi pemuda disabilitas melalui pelatihan. Membuat variasi produk dan belajar mengemas produk dengan alat yang telah disediakan. pemanfaatan pemasaran online dengan Menjual produk di media sosial atau whatsapp bussiness secara mandiri