bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Method for Characterizing the Mechanical Properties of the Cement Sheath Based on Hollow-Cylinder Specimen and Multiaxial Load Tests
Authors: Su Donghua , Li Jin , Huang Sheng , Li Zaoyuan , Wu Xuning 
Published: December 2022

Summary
Mechanical properties such as Young's modulus, Poisson's ratio, and strength are important parameters for evaluating the cement sheath integrity. However, the current triaxial testing methods for the mechanical properties of intact-cylinder cement specimens ignore the “ring” shape of the wellbore cement sheath and its nonuniform 3D stress distribution, which may lead to deviations from the actual mechanical properties of the wellbore cement sheath that can affect the theoretical analysis results. In this study, we designed a hollow-cylinder cement specimen to address the aforementioned conditions and conducted uni, tri, and multiaxial compression tests to analyze the differences in the deformation, damage, and mechanical failure of the hollow- and intact-cylinder cement specimens. It was found that under the same confining pressure, the Young’s modulus of the hollow-cylinder cement specimen with hole pressure was approximately 1.2 times that of the intact-cylinder cement specimen; however, the difference in Poisson’s ratio was not significant. The uniformity of the radial and circumferential stress distributions in the hollow-cylinder cement specimens was the main factor affecting the volumetric strain curves and the damage threshold. Under tri and multiaxial compression conditions, the deviatoric stress of the hollow-cylinder cement specimens was higher than that of the intact-cylinder cement specimens. Compared with the Mohr-Coulomb criterion, the twin-shear unified strength theory can more accurately reflect the relationships between the radial, circumferential, and axial stresses and the strength of the hollow-cylinder cement specimens. Through a failure test of the cement sheath based on a self-developed wellbore simulation device, it was verified that the mechanical properties of the hollow-cylinder cement specimens can better reflect the failure law of the wellbore cement sheath compared with intact-cylinder cement specimens. The findings of this study can contribute to the understanding of the mechanical behavior of wellbore cement sheaths.
Real-Time Outdoor Localization Improvement for IoT Anchor Nodes
Authors: Zorkany Mohamed , Abd-Elrahman Emad , A.Fahmy Ghazal 
Published: December 2022

Abstract
Real-time localization improvement is needed in most Internet of Things (IoT) applications that require accurate knowledge of the physical location of IoT devices, especially in the areas that having a weak GPS signals or in moving objects like smart bike-sharing, robots, and off- roads vehicles. Recently, most outdoor localizations use a hybrid mechanism integrating some IoT devices occupying with GPS (Anchor Nodes) and others IoT devices with wireless sensors nodes like LoRaWAN (without GPS-Unknown node). This hybrid method employed to achieve low power consumption and low cost solution. Our proposed work focuses on determining the Anchor node locations with high accuracy to enhance the overall accuracy of all IoT nodes. To achieve this goal, the installation of low power consummations and low-cost localization sensors modules will be used in the proposed Anchor IoT node. These modules as inertial measuring unit (IMU) will integrate with a low cost Global Positioning System (GPS) module to enhance the locations accuracy of these IoT devices. Then, the proposed method will be implemented on AVR microcontroller (ATMega 128) to develop an IoT enhanced localization unit. The general structure of the proposed method from a mathematical point of view is presented with recursive algorithm update equations. Moreover, this paper will show how the IoT device’s state can be known accurately and at a high update rate (100Hz, 10 milliseconds).
Landslide deformation mechanism in buoyant and slide-prone strata in the Three Gorges Reservoir area, China
Authors: Xu Xiao-chuan , Xu Guang-li , Feng Fei , Xu Wei-dong , Mabi Awei 
Published: December 2022

Abstract
This paper describes the Baibao landslide that occurred in October 2017 within a Jurassic formation in Guojiaba town, Zigui County, Yichang city, China. The factors leading to this landslide include complex geological conditions, slide-prone strata, and fluctuating water level of the Three Gorges Reservoir. Borehole and field investigations indicate that the landslide can be divided into two parts: a medium to deep rock landslide and a partial soil sliding landslide. A comprehensive analysis of the monitoring data, including GPS, precipitation, inclinometer, and water reservoir level measurements, indicates that the Baibao landslide was caused mostly by buoyancy, as well as seepage. Rising reservoir water levels and concentrated pore water pressure at the leading edge of the slope softened the sliding mass. The reduced anti-sliding force allowed the landslide to occur and ultimately drag the rear slope. This study illustrates the landslide deformation mechanism and provides a useful reference for engineering projects in similar regions.
Predictors of Physical Violence Against Children in Rwanda: Findings from a National Cross-Sectional Survey
Authors: Nyandwi Alypio , Fredinah Namatovu , Rusanganwa Vincent , Munyanshongore Cyprien , Nyirazinyoye Laetitia , Ndola Prata , Nshimiyimana Jean Damascene , Ingabire Marie-Gloriose , Nyirabahinde Anastasie , Salant Natasha , Mecthilde Kamukunzi , Emmanuel Hakomeza , Mukabutera Assumpta 
Published: December 2022

Abstract
Background: To address the challenges of limited national data on the prevalence and nature of violence experienced by children, Rwanda conducted, in 2015-2016, the first National Survey on Violence among female and male children and youth aged 13-24 years. To further contribute to these efforts to fill existing data gaps, we used the Rwanda survey data to assess the prevalence and predictors of physical violence (PV) in children aged 13-17.
Methods: A nationally representative sample of 618 male and 492 female children were analysed. Nationally representative weighted descriptive statistics were used to analyse the prevalence of PV self-reported by children, and logistic regression models were applied to investigate its predictors.
Results: Sixty percent of all children, including 36.53% of male and 23.38% of female children, reported having experienced any form of PV in their lifetime. Additionally, 21.81% of male children and 12.73% of children reported experiences of PV within twelve months before the survey date. Older children (OR: 0.53 [0.40-0.72]), female children (OR: 0.43 [0.31-0.58]), and children not attending school (OR: 0.48 [0.31-0.73]) were less likely to be physically abused. However, sexually active children (OR: 1.66 [1.05-2.63]), children in households from the middle wealth quintile (OR: 1.63 [1.08-2.47]), children living in a larger family (OR: 1.55 [1.07-2.26]), and children who reported not feel close to both biological parents (OR: 2.14 [1.31-3.49]) had increased odds of reporting physical violence.
Conclusions: Higher rates of PV in children attending school werethe key finding. There is an urgent need to design and implement particular national interventions to prevent and reduce the incidence of PV in schools in Rwanda. PV was also associated with poor parent-child relations. Parents and other adult caregivers should be sensitisedto the consequences of PV on children and be urged to adopt positive parenting practices.
Fabry Disease: Screening and Analysis of the Associated Clinical Manifestations in Patients Attending Dialysis and Nephrology Clinics in Durban, South Africa
Authors: Singh Jillian , Benjamin Sherilene , Assounga Alain 
Published: December 2022

AbstractBackground Fabry disease is inherited in an X-linked manner in which the mutated gene inhibits the functioning of the alpha-Galactosidase-A enzyme causing a deficiency or absence of the enzyme, characterising it as a progressive, lysosomal storage disorder. Subsequently, the accumulation of globotriaosylceramide (Gb3) in the lysosomes causes damage to tissues and major organs. Fabry nephropathy is one of the major organ complications caused by Fabry disease resulting in end-stage kidney disease. To our knowledge, no research has been conducted to determine the association between Fabry disease, its clinical manifestations, and chronic kidney disease in Durban. Methods This study was a prospective, quantitative study. A cohort of 200 male patients with chronic kidney disease (CKD stage 2-5D) was enrolled. A control group of 14 healthy males was also enrolled for this study. The ELISA technique was employed to determine the alpha Gal-A enzyme concentration levels in plasma. A questionnaire using the MSSI scoring system was presented to the participants to identify clinical manifestations. The SPSS Version 27 (IBM, New York, USA) was used to analyse the data. Results A cut-off value for the alpha Gal-A enzyme concentration levels of < 500pg/ml was calculated. A total of 17 participants from the patient group (n = 11) and the control group (n = 6) displayed alpha-Gal-A enzyme levels < 500pg/ml. The univariate regression analysis revealed, statistically significant association between alpha-Gal levels < 500pg/ml and age (p = 0.007), heat or cold intolerance (p = 0.049), hypertension (p < 0.001) and eGFR (p < 0.001). MSSI scores displayed a negative association (p = 0.001). The multivariate regression analysis showed that age and MSSI scores retained their significance when eGFR was excluded as a variable, however, with the inclusion of eGFR as a variable, none of the variables retained their significance. Conclusion Fabry disease is suspected in 17 participants with alpha-Gal levels of < 500pg/ml. The cause of CKD nephropathy raises interest as conditions such as FSGS have been associated with FD. The low levels of the alpha-Gal enzyme and the presentation of the clinical manifestations can be utilised as preliminary findings. Confirmatory tests such as DNA analysis or Gb3 and GL3 analysis should be performed to confirm the diagnosis.
The Effects of Wechat intervention for dementia family caregivers based on PAC model: A Randomized Controlled Trial
Authors: Zhuang Bisang , Su Cui , Li Chunwei , Wan Rick , Leung Angela Yee Man , Deng Renli 
Published: December 2022

Abstract
Background: Caregivers of people with dementia experience high stress levels. Network intervention can effectively improve the mental health of caregivers, which is a very feasible way for dementia caregivers who need help.
Objective: The aim was to explore the feasibility and effects of Wechat official account network interventionon family caregivers of people with dementia.
Methods: In a prospective, not-blinded, parallel-group, randomized controlled trial, 116 caregivers of people with dementia were randomized to either the intervention group, receiving Wechat official account network intervention for 3 months; or the control group, receiving the home visits by traditional community workers, telephone follow-up by hospital nurses. Various psychological outcomes of caregivers were assessed and compared at baseline, immediately post-intervention, and at the 3-month follow-up.
Results: There was no significant difference in the level of positive feelings, competence, and care satisfaction between the two groups before intervention (P > 0.05). The intervention group experienced a statistically significant increase in positive feelings levels (T=-3.21, P = 0.001), competence(T=-2.71, P = 0.007) and care satisfaction (T=-3.79, P <0.001) at the post-test. At the 3-month follow-up, the intervention group had a increase in positive feelings levels (T=-4.21, P = 0.000), competence (T=-3.52, P <0.001) and care satisfaction (T=-4.22, P <0.001) compared to the controls.
Conclusion: The findings support the feasibility and effects of Wechat official account network interventionon improving caregivers' positive feelings, competence, and the level of care satisfaction. A future study with a larger and more diverse sample should be developed to evaluate the longer-term effects and generalizability of the Wechat official account network intervention and the impacts on people with dementia.
Residual penile curvature correction by modeling during penile prosthesis implantation in Peyronie’s disease patients
Authors: Hellstrom Wayne , Conlon William , Herzog Bryan 
Published: December 2022

Abstract
With the advent of new surgical techniques to treat Peyronie’s disease with concomitant erectile dysfunction, there remains a question of whether manual modeling, an older technique, still has a place in the treatment algorithm within penile prosthesis surgery. While the implantation of a penile prosthetic often corrects moderate to severe curvature, penile curvature, in some cases, remains greater than 30°. In these cases, manual modeling should be the first line of treatment for persisting intraoperative penile curvature after the placement of a penile prosthetic due to its long-term efficacy, noninvasive approach, and lack of adverse effects.
The Chain Mediating Effects of External Locus of Control and Psychological Entitlement between Parental Over-Protection and Academic Entitlement among Nursing Students: A cross-sectional Study
Authors: Peng Biao , Pang Bing , Lv Mingzhi , Li Hong , Wang Xiuhong , Hu Ningning 
Published: December 2022

Abstract
Background
Academic entitlement in nursing students has been shown to cause problems such as superficial learning, lack of theoretical knowledge, and weak practical abilities, all of which affect the overall quality of nursing talents in the future, thereby affecting the quality of nursing services and patient safet. However, few studies have focused on the academic entitlement of Chinese nursing students and its influencing mechanisms.
Purpose
To explore the influence of parental over-protection on academic entitlement of nursing students, and to examine the mediating roles of external locus of control and psychological entitlement.
Methods
This study employed a cross-sectional, descriptive correlational design. The study sampled two medical universities in Guizhou and Yunnan provinces, China. Participants were nursing students in grades one to four (N = 1,003; mean age = 19.51 years; 81.95% female). Using a structural equation model, we examined the mediating effect of external locus of control and psychological entitlement on parental over-protection and academic entitlement.
Results
Chinese nurses have been shown to have a higher level of academic entitlement than American students. There was a significant correlation between all variables, and external locus of control and psychological entitlement played a chain mediating role between parental over-protection and academic entitlement.
Conclusion
The academic entitlement of nursing students in China demands urgent attention. An over-protective parenting style, an externally controlled attribution style, and psychological entitlement are key factors which lead to nursing students’ academic entitlement. Our findings suggest that academic entitlement of nursing students can be reduced by adjusting parental rearing behaviors, reducing students’ psychological entitlement, and teaching them how to form a healthier attribution style.
Expression and prognosis of cellular senescence genes in head and neck squamous cell carcinoma
Authors: Feng Chen , Mao Wei , Xiao Qiyi , Liu Yuanyuan , Yan Minzhu , Dong Pin , Liu Yuying , Chen Xinwei 
Published: December 2022

Abstract
Background: Cellular senescence refers to cells entering a relatively stable state of cell cycle arrest, which is a barrier that tumor cells must cross to achieve immortalization and plays an extremely important role in preventing the occurrence and development of tumors. In recent years, numerous studies have shown that inducing tumor cells to enter a senescent state has become a feasible tumor control strategy. At present, cellular senescence has become a research hotspot in tumor prevention and treatment, as well as in cell biology. However, the expression and prognostic values of cellular senescence genes in head and neck squamous cell carcinoma (HNSC) remain unclear.
Material/Methods: We analyzed the expression patterns and prognostic values of cellular senescence genes in HNSC from TCGA and GEO. The TCGA-HNSC data wereused as the training group and were divided into high- and low-risk groups, and the GEO database was used as the test group. Analyses included survival analysis, ROC curve analysis, risk curve analysis, independent prognostic analysis and model validation for clinical grouping. We used the HPA database for protein-level validation of the genes.
Results: We identified 5 cellular senescence genes associated with HNSC, namely,BTG3, EHF, EZH2, TACC3 and TXN. These cellular senescence genes were analyzed in the training and test groups and were found to be significantly associated with the prognosis of HNSC patients.
Conclusions: The tumor immune microenvironment of HNSC is closely related to cellular senescence-related features. Cellular senescence genes (BTG3, EHF, EZH2, TACC3, and TXN) have the potential to be diagnostic and prognostic biomarkers for HNSC.
Asset Dependence Prediction Utilizing Spatiotemporal Patterns
Authors: Zhu Haoren , Liu Shih-Yang , Zhao Pengfei , Chen Yingying , Lee Dik Lun 
Published: December 2022

Abstract
Financial assets exhibit dependence structures and knowing the dependencies of the assets can help investors to create a diversified portfolio that can reduce portfolio risk due to the high volatility of the financial market. Since asset dependency changes with time in complex patterns, asset dependency forecasting is an important problem in finance. In this paper, we organize pairwise asset dependencies in an Asset DependencyMatrix (ADM ) and formulate the problem of asset dependency fore-cast as the prediction of future ADM s given a sequence of past ADM s.To exploit the spatiotemporal dependencies between the assets, we propose a novel idea that views ADM sequence as an image sequence, where an ADM corresponds to an image and an entry in the ADM to a pixel. This enables us to apply video prediction methods to capture the spatiotemporal dependencies among the assets. In this paper, we propose a novel Asset Dependency Neural Network (ADNN) to tackle the ADM prediction problem. It adopts ConvLSTM, a highly successful method for video prediction, and the novelty of ADNN is the introduction of a transformation function between ADM and ConvLSTM and an end-to-end approach to learn the transformation function. We conducted extensive experiments to evaluate the performance of ADNN and show that our proposed framework consistently outperforms the baselines on future ADM prediction and portfolio risk reduction tasks.
A pilot study: Self Empowerment Therapy for depression associated with PTSD
Authors: Kaye Professor David 
Published: December 2022

Abstract
Background
Mental Health issues such as depression, PTSD, suicide etc., have become epidemics crippling western society requiring significant allocation of funds to address them. Research shows that that regardless of therapy used, nature and severity of the presenting problem and diagnosis, the modal frequency of patients attending counselling services is 1 (Talmon, M.,1990; Bloom, B.L., 2001; Young, J., 2018). With this in mind, Self Empowerment Therapy (SET) was developed by the author (Kaye, D., 2021).
Aims
The aim of this study was to look at effectiveness of SET as a single session in the treatment of depression.
Method
A cohort of 82 subjects were assessed using the Beck Depression Inventory at the start of the single-session and at the conclusion of the single-session.
Single session SET consisting of recording baseline measures, administration of 3 clinical exercises, questionnaire administration and results analysis.
The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008. All subjects executed informed consent forms.
Results
Results of the tests showed (n=82) showed clinically significant therapeutic effects from SET with 76.82 % improvement in depression symptoms.
Conclusions
Results for the in-person single shot two hour SET depression intervention demostrated clinically significant impact on depression associated with PTSD.
A Efficient Lattice-based Forward-Secure Linearly Homomorphic Signature Scheme for Network Coding
Authors: Wu Bin , Wang Caifen , Li Yahong , Shi Ning 
Published: December 2022

Abstract
The property that linearly homomorphic signature (LHS) enables linear computation on signed data makes this primitive commonly used to secure the network coding based application against pollution attacks. The security of LHS wholly depends on the security of secret signing keys; once a secret key is compromised, the application system’ security will be broken. However, as relatively insecure mobile devices are increasingly used in network coding application systems, the key exposure issue is becoming more prevalent. On the other hand, with the quantum technology development, some existing LHS schemes based on some traditional number-theoretic primitives are susceptible to quantum cryptanalysis. Hence, facing the dual threats of the exposure of secret keys in reality and the future effiffifficient quantum computers, we integrate forward security into LHS, and present a forward-secure identity-based LHS scheme (FSIBLHS) based on lattice assumptions, which achieves post-quantum security, and even if the current secret key is compromised, the validity of signatures of previous time periods is still guaranteed. We defifine the fifirst security model on forward security of LHS, and prove that the proposed scheme can resist adaptively chosen identity and datasets attack under lattice assumption. Moreover, compared with previous related works, the performance analysis shows that our scheme enjoys a comparable computation cost and has a lower communication cost, and provides higher security and stronger functionality.
Comparison of the effects of different combinations of expression regulatory elements on gene expression in mammalian cells
Authors: Zhou Lu-Yu , Zhang Shuang , Li Li-Yun , Liang Dong-Ge , Yu Hai-Shen , Chai Ya-Jing , Zhao Shi-Bo , Pan Jia-Jia , Zhu He-Shui , Zeng Lei 
Published: December 2022

Abstract
Background
At present, the function of numerous individual regulatory elements has been characterized extensively, but the combined effect of various cis-regulatory elements on gene expression in mammalian cells has been less discussed.
Results
In the present study, we examined the function of the combined effect of various cis-regulatory elements on gene expression in mammalian cells. To detect the function of different combinations of cis-acting elements on gene expression, we compared the effects of four promoters (PGK, Polr2a and EF-1α core promoter), two enhancers (CMV and SV40 enhancer), two introns (EF-1α intron A and hybrid intron), two terminators (CYC1 and TEF terminator) and their different combinations on gene expression. We constructed expression vectors with different combinations of these regulatory elements and detect the expression of eGFP by fluorescence intensity contrast and western blotting. Here we report that different combinations of cis-acting elements have a significant effect on protein expression. The vector with CMV enhancer, EF-1α core promoter and TEF terminator can express about three times higher eGFP than the unmodified vector in different animal cells.
Conclusions
We demonstrate that a direct combination of multiple regulatory elements capable of regulating gene expression did not exhibit synergistic effects. Our results show that regulation of protein expression can be achieved by optimizing the combination of cis-acting elements, and these findings can be used in biological applications that require regulation of gene expression.