bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advances in Lanthanum Ferrite‐Based Sensors: A Comprehensive Review
Authors: Yadav Avadhesh Kumar , Singh Prabhakar , Pandey Raghvendra 
Published: January 2025

AbstractLanthanum ferrite has emerged as a promising material for the development of advanced sensor technologies due to its unique electrical, magnetic, and optical properties. This comprehensive review explores the recent advancements in lanthanum ferrite‐based sensors, highlighted their potential applications in various fields, including gas sensing, humidity sensing, biomedical diagnostics and environmental monitoring. The review delves into the underlying principles of lanthanum ferrite sensors, their fabrication techniques, and the strategies employed to enhance their sensitivity, selectivity, and stability. Particular emphasis is placed on the integration of lanthanum ferrite with complementary materials and the utilization of advanced characterization techniques to unlock the full potential of these sensor systems. Current challenges and future research directions in this rapidly evolving field are also discussed, aiming to provide a roadmap for further developments and widespread adoption of lanthanum ferrite‐based sensors.
Molecular Structure, Docking, Spectroscopic Characterization, Antibacterial, and Anticancer Activity of Copper(I, II), Silver(I), and Cadmium(II) Complexes
Authors: Hassan Safaa S. , Aly Samar A. , Ismail Rabab A. , Aboelyazed Ahmed M. , Youssef Mona H. , Abdalla Ehab M. 
Published: January 2025

ABSTRACTSeven new complexes of [Cu(H2L)2]I.2H2O (C1), [Cu(H2L)(HL)]ClO4.2H2O (C2), Ag(H2L)NO3 (C3), Ag2(H2L)(OAc)2 (C4), Cd (HL)(OH) (C5), Cd (HL)NO3 (C6), and Cd (HL)Cl (C7) of [N‐phenyl‐2‐(phenylglycyl)hydrazine‐1‐carbothioamide](H2L) have been synthesized and characterized by various techniques. All metal complexes are mononuclear in nature, except complex [Ag2(H2L)(OAc)2] (C4), which is binuclear. The complexes (C5–C7) adopt tetrahedral, square planar geometry in the copper complex (C1–C3). The DFT calculation is performed and supports the expected structures. Stability study of C3 and C7 in alkaline, acidic, and neutral pH through more than 24 h is investigated. The ligand and its metal compounds were examined for their effectiveness against three different types of bacterial strains: Gram negative (Escherichia coli) and Gram positive (Streptococcus pyogenes and Bacillus polymyxa). The findings demonstrated that the metal complexes, in comparison to the ligand, exhibited more effective antibacterial and anticancer properties against three distinct human cancer cell lines: liver, breast, and colon. Cu(I) complex (C1) exhibited the greatest anticancer effect with the lowest IC50 value among the three investigated cell lines. The theoretical molecular docking studies revealed the active amino acids that interact with the synthesized compounds.
Plasma Assisted Surface Decoration of PLA Nonwoven Materials With Selenium Nanoparticles for Improvement of Antibacterial and Biocompatible Properties
Authors: Luan Rui , Zhao Ziyao , Yuan Yuan , Wang Chunxia , Li Mei‐Xian , Ren Yu 
Published: January 2025

ABSTRACTThis study aimed to enhance the antibacterial and biocompatible properties of PLA nonwoven materials by plasma‐assisted surface decoration with selenium nanoparticles. PLA nonwoven materials were pretreated by plasma surface modification technology for varying durations. Subsequently, Se nanoparticles obtained from the redox reaction of sodium selenite were loaded onto the PLA surfaces through impregnation. SEM images demonstrated that plasma pretreatment enhances the uniformity of Se nanoparticles as well as the contents loaded onto the PLA nonwoven materials. Based on EDS analysis, the relative concentration of Se elements increased with longer plasma pretreatment durations, reaching 6.38% after 6 min of treatment. XPS analysis confirmed the presence of elemental selenium nanoparticles. Furthermore, the results of surface wettability showed that the surface of Se/PLA composites changed from hydrophobic to super hydrophilic after the plasma and Se combined treatment. Moreover, bacterial inhibition of the Se/PLA composites substantially improved with increasing plasma pretreatment time. The Se/PLA composites with 6 min of plasma pretreatment showed the best antibacterial performance and biocompatibility, with inhibition rates against Staphylococcus aureus and Escherichia coli reaching 95.75% and 75.54%, respectively, and cell viability was over 99% for L929 cells. These functionalized Se/PLA composites exhibit tremendous potential for applications in novel antibacterial materials.
Material Extrusion Additive Manufacturing of Composite Laminates: Printability and Characterizations
Authors: Haile Frank , Igwe Arize C. , Wambua Job , Mwema Fredrick , Akinlabi Stephen A. , Akinlabi Esther T. 
Published: January 2025

ABSTRACTThis study characterizes composite laminates produced via Material Extrusion Additive Manufacturing (MEAM) using combinations of polylactic acid (PLA), recycled PLA (rPLA), and ultrafuse 316 L stainless steel. A thorough analysis of the effect of layer frequency on the material behavior of the PLA/rPLA, PLA/316 L stainless steel, and rPLA/316 L stainless steel composites was conducted. Owing to the disparity in deposition temperatures, PLA and rPLA layers exhibited poor adhesion to 316 L stainless steel layers, likely exacerbated by warping during printing. Excess material deposition at layer pauses caused bobbles at the corners of material interfaces, which in certain samples led to the formation of ridges. Additionally, layer sliding was observed, attributed to weak adhesion both to the print bed and at some layer interfaces. The rPLA layers demonstrated superior load‐bearing capacity, while composite laminate block samples with higher interlayer frequencies exhibited enhanced resistance to compressive forces. This study provides insights into the challenges and mechanical performance of multi‐material composite laminates, highlighting areas for process optimization and material improvement.
Special Collection: XIX Brazilian Meeting on Organic Synthesis (BMOS)
Authors: Schneider Paulo H. , Lüdtke Diogo S. , da Silva Júnior Eufrânio N. 
Published: January 2025

AbstractIn this guest editorial, Paulo H. Schneider, Diogo S. Lüdtke, and Eufrânio N. da Silva Júnior introduce the joint special collection of Chemistry – An Asian Journal, Asian Journal of Organic Chemistry, and The Chemical Record, dedicated to the 19th Brazilian Meeting on Organic Synthesis (19th BMOS).
Classification of urban underlying surfaces in Beijing and its impact on summer high temperature and heat wave event
Authors: Zheng Zuofang , Xu Guirong , Li Nana , Gao Hua 
Published: January 2025

AbstractWith analysis of local climate zone (LCZ) classification, approximately 52.0% of underlying surfaces in Beijing are covered by buildings with LCZ 5 (open midrise) accounting for the highest proportion, and LCZ D (low plants) is the most distributed among natural surface types. Compared to natural underlying surfaces, building underlying surfaces have higher values in the high temperature (HT) and heat wave (HW) days, HW intensity, and maximum HW duration. In recent decades, HT days on building underlying surfaces in Beijing start earlier and end later than those on natural underlying surfaces. Building underlying surfaces make greater contribution to urban heat island intensity of apparent temperature than to that of temperature, yet it is opposite for natural underlying surfaces.
Climate change attribution of Typhoon Haiyan with the Imperial College Storm Model
Authors: Sparks Nathan , Toumi Ralf 
Published: January 2025

AbstractIt is difficult to model changes in the likelihood of tropical cyclones under climate change to date. We do this, for the first time, by a applying a stochastic tropical cyclone event set generated by the Imperial College Storm Model to attribute the contribution of climate change to the case of Typhoon Haiyan in 2013. Compared to a pre‐industrial baseline, we estimate that a typhoon with a landfall maximum wind speed like Haiyan was larger by +3.5 m/s. This is in good agreement with previous full physics numerical model estimates. A Haiyan type of event has a current return period of 850 years, and the fractional attributable risk due to climate change is 98%. Without climate change, this event was very unlikely. The type of information available from the IRIS model could inform subsidizing of catastrophe bond yield in the context of the loss and damage fund.
Enhancing electrochemical xanthine detection: A two‐step incubation strategy to minimize interference from ascorbic acid
Authors: Yoo Taeyeon , Park Seonhwa , Lee Hyoeun , Park Subin , Kim Youngsuk , Yang Haesik 
Published: January 2025

AbstractEnzyme‐based biosensors with mediated electrochemical detection offer a straightforward and cost‐effective approach for detecting xanthine. However, electro‐active interfering species such as ascorbic acid (AA) complicate the achievement of sensitive and selective detection in biological fluids. Direct and mediated oxidation of AA elevates electrochemical background levels. While ascorbate oxidase (AOx) is employed to oxidize AA into an electro‐inactive product, incomplete removal of AA allows it to reduce the electron mediator, resulting in still considerable background levels. Additionally, excess AOx can oxidize the signaling species, the reduced form of the electron mediator, albeit slowly, leading to decreased signal levels. To address these challenges, a two‐step incubation process and the use of appropriate AOx concentration are implemented. Once AA is fully oxidized by AOx, an electron mediator is added to the solution. To enhance the electrochemical signal‐to‐background ratio, an optimal pairing of a xanthine‐oxidizing enzyme and an electron mediator is selected from two xanthine‐oxidizing enzymes [xanthine dehydrogenase (XDH) and xanthine oxidase] and three electron mediators [Os(bpy)2Cl2+, Ru(NH3)63+, and Fe(CN)63−]. The combination of XDH and Os(bpy)2Cl2+ provides high signal and low background levels. When these conditions are applied to xanthine detection in artificial serum, a detection limit of approximately 500 nM is achieved, making it applicable in various clinical and research fields.
Best Evidence Summary for the Improvement and Management of Disorders of Consciousness in Patients With Severe Brain Injury
Authors: Lin Miaoyuan , Lu Qiongna , Yu Sheng , Lin Wenjuan 
Published: January 2025

ABSTRACTBackground and PurposeThe treatment effect of consciousness after brain injury is currently uncertain. Thus, this study aimed to retrieve the evidence from neurologists around the world on the management of consciousness disorders in patients with severe brain injury and evaluate and summarize the evidence, providing the guidance on the related management for clinicians.MethodsFollowing the evidence summary report standard of Fudan University Center for Evidence‐Based Nursing, clinical guidelines, expert consensuses, systematic reviews, and evidence summaries were systematically retrieved from UpToDate; BMJ Best Practice; Guidelines International Network; the Cochrane Library; Embase; PubMed; Sinomed; Web of Science; CNKI; WanFang database; American Academy of Neurology (AAN); American Congress of Rehabilitation Medicine (ACRM); European Academy of Neurology; and National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR). The publishing timeline for articles was limited from January 2017 to January 2024.ResultsFourteen articles were finally identified. The 26 best pieces of evidence were recommended by inducting and integrating the evidence from these articles, covering the following seven aspects: consciousness assessment, multidisciplinary team, intervention in facilitating arousal, sensory stimulation programs, drug administration, rehabilitation program, and prevention of complications.ConclusionThis study summarized the evidence of consciousness management in patients with brain injury, providing guidance for clinicians to develop and apply those interventions to improve the patient's clinical outcomes and quality of life. In addition, relevant factors such as the clinical environment and cooperation with the patient's family members should be evaluated and adjusted before applying such evidence. Future studies should focus on more targeted randomized clinical trials.
Domain‐Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach
Authors: Tahedl Marlene , Bogdahn Ulrich , Wimmer Bernadette , Hedderich Dennis M. , Kirschke Jan S. , Zimmer Claus , Wiestler Benedikt 
Published: January 2025

ABSTRACTPurpose: Due to the highly individualized clinical manifestation of Parkinson's disease (PD), personalized patient care may require domain‐specific assessment of neurological disability. Evidence from magnetic resonance imaging (MRI) studies has proposed that heterogenous clinical manifestation corresponds to heterogeneous cortical disease burden, suggesting customized, high‐resolution assessment of cortical pathology as a candidate biomarker for domain‐specific assessment.Method: Herein, we investigate the potential of the recently proposed Mosaic Approach (MAP), a normative framework for quantifying individual cortical disease burden with respect to a population‐representative cohort, in predicting domain‐specific clinical progression. Using MRI and clinical data from 135 recently diagnosed PD patients from the Parkinson's Progression Markers Initiative, we first defined an extremity‐specific motor score. We then identified cortical regions corresponding to “extremity functions” and restricted MAP, respectively, and contrasted the explanatory power of the extremity‐specific MAP to unrestricted MAP. As control conditions, domain‐related but less specific general motor function and nondomain‐specific cognitive scores were considered. We also tested the predictive power of the restricted MAP in predicting disease progression over 1 and 3 years using support vector machines. The restricted, extremity‐specific MAP yielded higher explanatory power for extremity‐specific motor function at baseline as opposed to the unrestricted, whole‐brain MAP. On the contrary, for general motor function, the unrestricted, whole‐brain MAP yielded higher power.Finding: No associations were found for cognitive function. The extremity‐specific MAP predicted extremity‐specific motor progression over 1 and 3 years above chance level. The MAP framework allows for domain‐specific prediction of customized PD disease progression, which can inform machine learning, thereby contributing to personalized PD patient care.
Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review
Authors: Shaalan Fatima , Ballout Nissrine , Chamoun Wafaa Takash 
Published: January 2025

ABSTRACTBackgroundGlioblastoma (GBM) is the most common primary brain tumor in adults and has a median survival of less than 15 months. Advancements in the field of epigenetics have expanded our understanding of cancer biology and helped explain the molecular heterogeneity of these tumors. B‐cell‐specific Moloney murine leukemia virus insertion site‐1 (Bmi‐1) is a member of the highly conserved polycomb group (PcG) protein family that acts as a transcriptional repressor of multiple genes, including those that determine cell proliferation and differentiation. We hereby aim to explore the specific involvement of Bmi‐1 in glioma pathogenesis.MethodsA comprehensive narrative review was employed using “PubMed”. Articles were screened for relevance specific keywords and medical subject headings (MeSH) terms related to the topic combined with Boolean operators (AND, OR). Keywords and MeSH terms included the following: “glioma”, “polycomb repressive complex 1”, and “Bmi1”.ResultsIn GBMs, several reports have shown that Bmi‐1 is overexpressed and might serve as a prognostic biomarker. We find that Bmi‐1 participates in regulating the gene expression and chromatin structure of several tumor suppressor genes or cell cycle inhibitors. Bmi‐1 has a critical role in modulating the tumor microenvironment to support the plasticity of GBM stem cells.We explore Bmi‐1's involvement in maintaining glioma stem cell (GSC) proliferation and senescence evasion upon regulating the chromatin structure of several tumor suppressor genes, cell cycle inhibitors, or stem cell genes in tumor cells. Additionally, we analyze Bmi‐1's involvement in modulating the DNA repair machinery or activating anti‐apoptotic pathways to confer therapy resistance. Importantly, our research discusses the importance of targeting Bmi‐1 that could be a promising therapeutic target for GBM treatment. Bmi‐1 activates and interacts with NF‐κB to promote angiogenesis and invasion, regulates the INK4a‐ARF locus, and interacts with various microRNAs to influence tumor progression and proliferation. In addition, Bmi‐1 confers radioresistance and chemotherapy by promoting cell senescence evasion and DNA repair.ConclusionBmi‐1 regulates self‐renewal, proliferation, and differentiation of GBM cells, promoting stemness and therapy resistance. Targeting Bmi‐1 could be a promising novel therapeutic strategy for GBM treatment.
Myocardial Bridging, Unusual Cause of Myocardial Infarction; Case Report and Review of Literature
Authors: Daba Merga , Bineyam Dawit , Yohannes Ibraist , Yohannes Beniam , Waktola Rabirra , Bedada Eshetu 
Published: January 2025

ABSTRACTMyocardial bridging is a common coronary anomaly. Although it is considered to be a benign condition, it can rarely be complicated by myocardial infarction. Clinicians should be suspicious of myocardial bridging as an etiology of myocardial infarction when other more common etiologies have been excluded. High resolution CT angiography is the gold standard for diagnostic evaluation, with the length and depth of the bridge, and response to conservative therapies guiding clinical decision making on surgical correction.Myocardial bridging is a congenital coronary anomaly in which the coronary arteries pass through the heart muscle rather than lying on its surface. It is typically a benign condition, and most patients are asymptomatic. However, some may experience symptoms of angina. In rare cases, patients can present with myocardial ischemia or infarction. In this report, we present the case of a 38‐year‐old female who presented with a 2‐month history of chest pain. Further evaluation with coronary computed tomography angiography (CCTA) revealed myocardial bridging. Subsequently, she developed a myocardial infarction, a rare complication of this condition. We discuss this uncommon complication of a common anomaly.
Recurrent Spontaneous Coronary Artery Dissection as the Cause of Repeated Myocardial Infarctions
Authors: Knudsen Arnon Møldrup , Støttrup Nicolaj Brejnholt , Hager Henrik , Mølgaard Henning , Stilling Christina 
Published: January 2025

ABSTRACTSpontaneous coronary artery dissection (SCAD) is characterized by intramural hematoma in a coronary artery leading to partial or complete vessel obstruction. A 51‐year‐old female was hospitalized with acute myocardial infarction and cardiogenic shock. She was diagnosed with severe SCAD, affecting the proximal left coronary artery. A complex percutaneous coronary intervention, complicated by cardiac arrest and need for cardio pulmonary support, succeeded with stent insertion and revascularization. In the following days, the patient developed severe heart failure due to extensive cardiac reperfusion injury and subsequently experienced multiple organ failure, ultimately resulting in death. The patient had previously been acutely hospitalized twice with myocardial infarctions and both the times was also diagnosed with SCAD affecting the left coronary artery. This case highlights an unfortunate patient outcome due to recurrent SCAD and serves as an important reminder to consider SCAD differential diagnostically in younger female patients with myocardial infarction.
Leprosy—Presenting as Rheumatoid Arthritis Misleading the Correct Diagnosis
Authors: Sagar Dhakal , Kipa Shrestha , Praful Gurung , Durga Thapa 
Published: January 2025

ABSTRACTLeprosy can present with symptoms resembling rheumatoid arthritis, leading to delays in diagnosis or inappropriate treatment, potentially progressing to lepromatous forms, neuropathy, and disability. Physicians must consider leprosy as a differential for rheumatoid arthritis, especially in endemic regions. Early detection is vital to prevent chronic neuropathy, disabilities, and disfigurement.
Pantoea eucrina: Catheter‐Related Bloodstream Infection in a Woman With Short Bowel Syndrome
Authors: Kølle Ida Saksenborg , Vinter‐Jensen Lars , Nielsen Morten Eneberg , Nielsen Hans Linde 
Published: January 2025

ABSTRACTPantoea eucrina, a member of the Erwiniaceae family, is a rarely reported human pathogen primarily associated with plants. This study presents a documented case of catheter‐related bloodstream infection caused by P. eucrina in a 60‐year‐old female receiving home parenteral nutrition. Despite presenting with only minor clinical symptoms, blood cultures from both central and peripheral sites confirmed the presence of P. eucrina, identified by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) and whole‐genome sequencing. The infection was successfully cleared following a 13‐day course of gentamicin lock therapy and intravenous piperacillin–tazobactam, after which the catheter was removed.
Digital documentation of railway tunnel inspection in Austria
Authors: Rebhan Matthias J. , Grubinger Stefan S. , Schüppel Andreas , Deutinger Simona , Schwarzenberger Gernot 
Published: January 2025

AbstractInfrastructure, especially railway tunnels, require continuous inspection to ensure their safety. Furthermore, the detection of damages at an early stage can improve their service life. These tasks represent a major challenge for those involved and the tunnel down time is a disruption in operation. In rail networks, comprehensive preparations are necessary to be able to plan closures and required compensation measures. To optimize this process, a workflow for a digital inspection was generated to allow a rapid localization and a corresponding time advantage when conducting the activities on site. In doing so, a multitude of bases can be used, a standardization of damage patterns is carried out and a collaborative cooperation of multiple inspection personnel is possible. Depending on the data stock, digitized as‐built models in the form of a plan, digital plan documents and existing or generated digital twins can be used. Making it possible to locate a damage already during the inspection and thus enable a comprehensible documentation and an automated generation of reports. The pre‐set options for attribution of damages enables a time‐optimized inspection on site—which enables a reduction of the required time, the associated restrictions on traffic routing and at the same time reduces the susceptibility to errors. Within this paper, results of a first series of field tests along the Tauern Line of ÖBB, using a digital inspection workflow, are presented.