bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study on the impact of cultural diversity on biodiversity gradient changes in heritage sites – a case study of Hubei Province
Authors: Wang Zichen , Liu Wenping , Wang Le 
Published: December 2022

Abstract
Context
Under territorial spatial planning, reasonable formulation of cultural heritage protection limits and control zoning is a crucial factor in constructing a security pattern for the cultural heritage system. However, the absence of consistent criteria for the method of conserving cultural assets jeopardizes the conservation of cultural heritage and its surroundings. Under territorial spatial planning, reasonable formulation of cultural heritage protection limits and control zoning is a crucial factor in constructing a security pattern for the cultural heritage system. However, the absence of consistent criteria for the method of conserving cultural assets jeopardizes the conservation of cultural heritage and its surroundings.
Objectives
The study of biocultural diversity investigates the mechanism of action between biodiversity and cultural diversity from an integrated perspective, analyzes the areas of biodiversity that change under the influence of various types of culture, and offers suggestions for the development of cultural heritage conservation zoning.
Methods
In the province of Hubei, biodiversity was represented by habitat quality and overlaid with a buffer zone within 15 kilometers of five distinct types of cultural heritage in order to determine individual and average biodiversity values for distinct types of cultural heritage under distinct buffer layers. The data were finally displayed using the R package and visualization software in order to determine the gradient and peak and valley values of the influence of various forms of cultural assets on biodiversity.
Results
The gradient changes of biodiversity in heritage sites were measured through the habitat quality of different cultural types of heritage sites in Hubei province, and it was discovered that: (1) there is a synergistic relationship between traditional villages, scenic spots, and temples and regional biodiversity, and there are peaks and valleys in the influence gradient; (2) the overall influence of cultural diversity on the gradient changes of biodiversity in heritage sites demonstrates peaks and valleys; and (3) the overall influence of cultural diversity on the gradient changes of biodiversity in heritage sites demonstrates
Conclusions
To promote the synergistic development of biocultural diversity in cultural heritage sites, different types should account for their unique influencing factors in the process of future cultural heritage protection and formulate their protection boundaries and control zoning in conjunction with the changing characteristics of biocultural diversity gradients.
Chinese TikTok (Douyin) Challenges and Body Image Concerns: A Pilot Study
Authors: Hu Shuchen , Gan Jasmine , Shi Victoria , Krug Isabel 
Published: December 2022

Abstract
Background: Social media content on Western platforms promoting thinness, or thinspiration, has been found to negatively affect body image perception of users. Less is known about non-Western social media use and its effects on body image concerns. Chinese TikTok, known as Douyin, is a popular short video platform with 600 million daily active users. Recent trends on Douyin encourage users to demonstrate thinness through participation in ‘body challenges’. This paper argues that such content is comparable to thinspiration, however, to date hardly any research has been undertaken on these challenges. Thus, this pilot study aimed to analyse the content of three viral challenges and investigate their impact on Douyin users.
Methods: Thirty most viewed videos were collected for three challenges (N=90): the Coin challenge, the A4 Waist challenge, and the Spider Leg challenge. Videos were coded for variables relating to thin idealisation, including thin praise, sexualisation and objectification, and analysed through content analytic methods. Video comments (N≈5500) were analysed through thematic analysis, and main themes were identified.
Results: Preliminary findings showed that participants who objectified their bodies to a greater extent expressed more negative body image concerns. In addition, comments on the videos had themes of thin praise, self-comparison, and promotion of dieting behaviours. In particular, videos of the A4 Waist challenge was found to incite more negative self-comparison in viewers.
Conclusion: Preliminary findings suggest all three challenges promote the thin ideal and encourage body image concerns. Further research about the broader impact of body challenges is needed.
Nursing Students' Perceptions of Job Adaptation: A qualitative Study
Authors: Xu Limin , Qian Zhigang 
Published: December 2022

Abstract

Aims
The objective of this study was to explore the perspectives of nursing students on clinical job adaptation to identify and understand their professional development needs.
Background
The process of job adaptation is a major challenge for nursing students. While clinical experience can stimulate their work stamina, they may also lose confidence in solving problems and overcoming obstacles in the workplace. Although they have received relevant training from the hospital, it is still worth exploring how to enhance job adaptation and make significant progress in their profession.
Design:
A qualitative research design was used.
Methods
Semi-structured interviews were conducted from February to May 2022 to understand their views on job adaptation. The manuscript was transcribed verbatim and imported into NVivo12.0plus software for encoding analysis and topic extraction. All methods were conducted in accordance with the ethical standards of the Helsinki Declaration and Consolidated criteria for reporting qualitative research (COREQ).
Results
This study extracted two themes regarding job adaptation for nursing students (a) personality difference, psychological distress, and competence are internal requirements for job adaptation; (b) the departmental atmosphere, interpersonal relationships, and management style are external manifestations of job adaptation.
Conclusions
In the absence of effective strategies and under great pressure, nursing students can easily switch careers. Admittedly, job adaptation is an indicator for assessing career development. This study discusses factors affecting job adaptation from an individual and environmental perspective. Based on this, nursing students should actively seek feedback to improve their coping and clinical communication skills. Managers should focus on coaching nursing students to face changes in the work environment. Additionally, clinical instructors should serve as role models and provide support to nursing students.
Consistent social context improves ensemble perception of facial expressions
Authors: Zhao Mengfei , Wang Jun 
Published: December 2022

Abstract
Observers could rapidly and automatically summarize statistical information from groups of similar objects with remarkable precisions through a specific ability, known as ensemble coding. Although previous studies demonstrated that matched physical backgrounds, such as oriented lines, between the encoding and retrieving phases of working memory improved the precisions of ongoing ensemble tasks, few studies have examined whether this facilitation effect still occurs when high-level social contexts utilized. In two experiments, participants performed an emotional judgment task about mean facial expressions that were paired with task-irrelevant movement trajectories of three dots. The information conveyed by the movement trajectories were either social (i.e., two white dots cooperatively chased a black dot) or non-social (i.e., reversed social movement trajectories). In Experiment 1, we manipulated the movement trajectories to be either consistent by presenting an identical social movement trajectory, or inconsistent by presenting one social and one non-social movement trajectories, in encoding and response phases. Participants showed a higher ensemble precision and better discrimination sensitivity when the movement trajectories were consistent than when they were inconsistent. In Experiment 2, similar manipulations were employed with one exception that two different movement trajectories but carrying a same type of social information were used in the consistent condition. The results of Experiment 2 revealed a similar and comparable effect as in Experiment 1. The present study extends the context matching facilitation effect on ensemble perception to social contexts, and suggests that the abstract social contexts in working memory exert a unique and obligatory influence on perceptual averaging.
Cancer Associated Macrophage-Like Cells in Metastatic Renal Cell Carcinoma Predicts for Poor Prognosis and Tracks Treatment Response in Real Time
Authors: Ali Amama , Adams Daniel L. , Kasabwala Dimpal M. , Tang Cha-Mei , Ho Thai H. 
Published: December 2022

Abstract
Background
Renal Cell Carcinoma (RCC) is a fatal urological cancer, with one third of patients diagnosed with metastasis, resulting in a 5-year survival of only 12%. Recent advancements in therapies have increased survival in mRCC, but lack efficacy in subtypes, due to treatment resistance and toxic side effects. Currently, white blood cells, hemoglobin, and platelets are limitedly used as blood based biomarkers to help determine RCC prognosis. Cancer associated macrophage-like cells (CAMLs) area potential mRCC biomarker which have been identified in peripheral blood of patients with malignant tumors and have been shown to predict poor clinical patient outcomes based on their number and size.
Methods
In this study, blood samples from 40 RCC patients were obtained to evaluate the clinical utility of CAMLs. CAML changes were monitored during treatment regimens to evaluate their ability to predict treatment efficacy.
Results
It was observed that patients with smaller CAMLs had better progression free survival (HR=2.84, 95%CI 1.22-6.60, p=0.0273) and overall survival (HR=3.95, 95%CI 1.45-10.78, p=0.0154) versus patients with larger CAMLs.
Conclusion
These findings suggest that CAMLs can be used as a diagnostic, prognostic, and predictive biomarker for patients with RCC which may help improve management of advanced RCC.
Using the National Mental Health Service Planning Framework to inform integrated regional planning: a case study in Tasmania, Australia.
Authors: Gossip Kate , Pagliaro Claudia , Comben Charlotte , Fjeldsoe Kevin , Whiteford Harvey , Diminic Sandra 
Published: December 2022

Abstract
Background
The aim of this study was to demonstrate the application of a needs-based mental health service planning model in Tasmania, Australia to identify indicative directions for future service development that ensure the equitable provision of mental health services across the State.
Methods
The activity and capacity of Tasmania’s 2018–19 mental health services were compared to estimates of required care by: (1) generating estimates of required care using the National Mental Health Service Planning Framework (NMHSPF); (2) collating administrative mental health services data; (3) aligning administrative data to the NMHSPF; and (4) comparing aligned administrative data and NMHSPF estimates to identify priority areas for service development. Findings were contextualised using information about service location, population demographics, and upcoming service development.
Results
Bed-based services capacity reached 85% of the NMHSPF estimate. However, access to certain bed types was inequitable across regional areas. Access to jurisdictional clinical ambulatory team-based services was lowest in the South, while overall full-time equivalent staff capacity reached 58% of the NMHSPF estimate. Access to Primary Health Tasmania (PHT) primary care services was highest in the North West; access to Medicare services was highest in the South. Collectively, activity across primary care (PHT, headspace and Medicare) reached 43% of the NMHSPF estimate. Over half of Community Managed Mental Health Support Services were state-wide services.
Conclusions
This study demonstrates the application of a needs-based planning model for mental health services. Findings revealed service priority areas across Tasmania and highlight considerations for needs-based planning.
Subpopulation analysis of Sca-1, Nanog, and Islet-1 positive cells in myocardial tissue
Authors: Liu Xinyi , Guo Wenjing , Dou Jintao , Xu Yaping , Guo Zhikun 
Published: December 2022

Abstract
To investigate the co-expression between different stem-cell or embryonic markers in myocardial tissue, which has rarely been discussed in previous studies, we selected three typical molecular markers, namely Sca-1, Nanog and Islet-1. In our study, we focused on the age-related changes of Sca-1, Nanog and Islet-1 expression and the co-localization levels between pin-two marker proteins to explore the heterogeneity and relevance between these three cell subpopulations. We found that Sca-1, Nanog, and Islet-1 positive cells were present in the cardiac tissue from newborn to adult mice, and their expression was negatively correlated with age. Co-localization existed between each two markers, and there were differences in co-localization levels at different stages of cardiac development. We thus hypothesize that these three positive cells are likely to be a group of cells, so that cardiac cells with myocardial differentiation potential should not be subclassified by a single cell marker, and their phenotypic changes at different stages may determine their unique roles in heart development.
Crystal plasticity based finite element modeling and experimental study for high strain rate microscale laser shock clinching of copper foil
Authors: Hou Yaxuan , Wang Jianfeng , Ji Zhong , Zhang Haiming , Lu Guoxin , Zhang Cunsheng 
Published: December 2022

Abstract
The microscale laser shock clinching (LSC) is a promising micro-forming technology that enables the deformation-based joining of ultra-thin sheets. In this research, a numerical crystal plasticity model of the LSC process at ultra-high strain rates is established to incorporate the actual grain size of the material and the anisotropic characteristics caused by different initial grain orientations. The simulations are in good agreement with the experiments, indicating that the crystal plasticity finite element method (CPFEM) can be used to study plastic deformation and predict the joint geometry during the LSC process. The results show that different zones of the joint exhibit different material flow behaviors, which are accordingly divided into three zones, namely the material inflow zone, the interlock forming zone, and the material stacking zone. The material at the neck and underside experiences the most severe thinning and is prone to failure as being located at the junction, where the material flows in opposite directions on both sides. It is also found that the holes with different diameter-to-depth ratios in the perforated steel sheets greatly affect the neck thickness, a key mechanical strength factor in formed joints.
Optimization of long-lasting insecticidal bed nets for resistance management: a modeling study and user-friendly app
Authors: Madgwick Philip , Kanitz Ricardo , Wubs Matthias 
Published: December 2022

Abstract
Background:
Up until the present, pyrethroid-treated bed nets have been a key tool for vector control in the fight against malaria. A global system that sets standards and facilitates procurement has successfully driven down the price of bed nets to enable more bed nets to be distributed. As a result of their mass rollout, malaria cases have been significantly reduced, but pyrethroid resistance is now widespread. Going forward, new insecticides have been and continue to be developed for use on bed nets, but it is unclear how to best deploy them for maximum impact.
Methods:
Here, an app for the optimization of bed nets based on their insecticide loading and deployment lifespan is presented. Underlying the app are simple models that incorporate the chemical and physical properties of bed nets, and the genetic and ecological properties of resistance evolution in mosquitoes. The app numerically searches across a massive number of these simple models with variable loading and lifespan to find their optima under different optimality criteria that place constraints on the options for vector control.
Results:
Optimization can lead to substantial gains in the average control of the mosquito population throughout the simulation, and these gains are comparatively greater with lower budgets for the purchasing of bed nets. Whilst optimizing a bed net with a new insecticide within the constraints of the incentives of the existing system of standards and procurement leads to substantially greater control than not optimizing the bed net, optimizing the bed net without constraints leads to yet substantially greater control. The most important factor in this optimization is coverage, which depends on the price per bed net. With this in mind, it is unsurprising that a pyrethroid is a preferred partner for a new insecticide because it is cost-effective in the balance of being less expensive than the new insecticide but also less effective due to pre-existing resistance. Surprisingly, a pyrethroid is shown to be an effective partner for a new insecticide because of its contribution to resistance management in delaying the onset of resistance to the new insecticide.
Conclusions:
This study highlights the importance of optimizing mixtures to maximize their impact in vector control. Further, it suggests that there are challenges in the roll-out of optimal bed nets because of the constraints imposed by the global system of standards and procurement, which currently fails to adequately incentivize important considerations in bed net design for new insecticides, like resistance management.
Synthesis, characterization and antibacterial assays of new N,N 1 -disubstituted 2,2’- dithiodianiline derivatives
Authors: Skrickus Karolis , Šiugždaitė Jūratė , Lelešius Raimundas , Anusevičius Kazimieras , Grybaitė Birutė , Vaickelionienė Rita , Mickevičius Vytautas 
Published: December 2022

Abstract
A series of novel 1,2-bissubstituted disulfanes bearing beta-amino acid, dihydropyrimidine-2,4-(1H,3H)-dione, hydrazide, hydrazone and azole moieties were synthesized. These disulphides were characterised by spectral and microanalysis data. On the antibacterial evaluation, they were found to have interesting antibacterial properties over a panel of the tested Gram-positive and Gram-negative bacteria: Staphylococcus aureus subs. aureus (ATCC 9144) and zoonotic agent Listeria monocytogenes (ATCC 35152), as well as Gram-negative ones, Escherichia coli (ATCC 13076) and zoonotic agent Salmonella enterica subs. enterica serovar Enteritidis (ATCC 8739). The antibacterial activity was evaluated by determining minimum inhibition (by broth microdilution) and minimum bactericidal (by growth on agar) concentrations. The assessment revealed that MIC values for L. monocytogenes varied between 3.9 and 62.5 µg/mL as well as for S. aureus ranged between 7.8 and 250 µg/mL, with the exception of one compound with much weaker MIC of 500 µg/mL. The MBC values for L. monocytogenes have been found to be of 7.8−250 µg/mL, while S. aureus demonstrated the higher resistance and MBCs varied in the range of 7.8\(\)500 µg/mL. The determined MBC/MIC ratios showed that eleven compounds were classified bactericidal agents for all tested bacteria.
Molar-incisor Hypomineralization: Prevalence and Etiology in Children Seen at the Children's Clinic of the University of Fortaleza
Authors: Lima Lucas Emmanuel Rodrigues , Ponte Marcela Bezerra de Menezes , Lima Luana Beatriz Ribeiro , Ribeiro Renata Roque , Veras Igor Cavalcante , Rocha Grace Sampaio Teles da , Ramalho Anastácia Leite Juca , Martins Maria da Glória Almeida , Arnez Ticiana Medeiros de Saboia 
Published: December 2022

Abstract
The aim of this study was to evaluate the prevalence and etiology of Molar-Inciscible Hypomineralization (MIH), (n = 178) children seen at the Children's Clinic of the University of Fortaleza, relating them to the degree of severity, patient gender and the group of teeth most affected. This cross-sectional observational study was carried out in children seen at the Pediatric Dentistry Clinic of the University of Fortaleza between February 08, 2022 and October 14, 2022, where patients were randomly included in the study. Parents scheduled appointments for their children regarding a routine dental checkup or dental treatment appointment. The anamnesis data obtained from the interview with the guardian or the parents of the patients were collected in the form of a questionnaire. The prevalence of MIH found was 21.9%. Regarding the association between the patient's medical history and the presence or absence of MIH, it was found that patients who used antibiotics had a higher percentage of positive diagnosis for MIH (69.2%). Most of the defects found (15.7%) had a mild degree of severity. There was no significant association between patient gender and prevalence of MIH. The most affected teeth were the upper first permanent molars, followed by the lower teeth and then the upper central incisors.
WITHDRAWN: The clinical characteristics and treatment response of patients with chronic obstructive pulmonary disease with low body mass index
Authors: Song Qing , Zhou Aiyuan , Li Xueshan , Cheng Wei , Liu Cong , Lin Ling , Peng Yating , Zeng Yuqin , Yi Rong , Liu Yi , Li Xin , Chen Yan , Cai Shan , Chen Ping 
Published: December 2022

Abstract
Background
This study aimed to analyze the clinical characteristics and treatment response of patients with chronic obstructive pulmonary disease (COPD) with low body mass index (BMI).
Methods
This cross-sectional study enrolled stable COPD patients from database setup by Second Xiangya Hospital of Central South University. According to the BMI, the patients were classified into three groups: low BMI (BMI < 18.5 kg/m2), normal BMI (18.5 ≤ BMI < 24.0 kg/m2) and high BMI (BMI ≥ 24 kg/m2) groups. Clinically important deterioration (CID) was defined as attaining CAT scores increased ≥ 2, minimum clinically important difference (MCID) was defined as attaining CAT scores decreased ≥ 2 during six months of follow up. Exacerbation and mortality were recorded during one year of follow up.
Results
A total of 910 stable COPD patients were included and 144 (15.8%) patients in low BMI, 475 (52.2%) patients in normal BMI and 291 (32.0%) patients in high BMI groups. The patients with low BMI had a worse pulmonary function, higher symptoms score and exacerbations in the past year compared with normal and high BMI groups (P < 0.05). Logistic regression analysis revealed that age, Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades 3 and 4, hospitalizations in the past year were the independent risk factors for low BMI (P < 0.05). After followed up for one year, the low BMI patients had higher mortality and number of hospitalizations. Patients with low BMI more likely to attain CID, while less likely to attain MCID compared with high BMI group (P < 0.05). In addition, the low BMI patients treated with long-acting β2-agonist (LABA) + long-acting muscarinic antagonist (LAMA) and LABA + LAMA + inhaled corticosteroid (ICS) more likely attain MCID than treated with LABA + ICS and LAMA (P < 0.05).
Conclusion
COPD patients with low BMI had worse pulmonary function, higher symptoms scores, higher risk of future hospitalizations and mortality, as well as less likely to attain MCID and more likely to attained CID. It was worth noting that low BMI patients treated with LABA + LAMA and LABA + LAMA + ICS more likely attain MCID than treated with LABA + ICS and LAMA.