bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of menstrual pain and symptoms on activities of daily living and on work absenteeism: A cross-sectional study
Authors: Leon-Larios Fatima , Silva-Reus Isabel , Martínez María José Puente , Roba Abel Renuncio , Martínez Eva Ibeas , Pascual Isabel Lahoz , Ratia Maria Cassia Naranjo , Conde Jose Cruz Quílez 
Published: August 2023

Abstract
Objective
To analyse the prevalence of menstrual pain in women of reproductive age, who use contraception methods or not, as well as its repercussion on their daily life and professional activities.
Methods
A cross-sectional and descriptive study conducted in July and August 2022. Phone interviews were carried out by means of a random system to select women aged between 15 and 49 years old. The questionnaire included sociodemographic variables, contraception method used and characteristics of the menstrual pattern (pain and bleeding amount), its influence on their working life and if they would need to resort to sick leaves due to the impairments arising from the menstrual symptoms.
Results
A total of 1,800 women representative of the Spanish population took part in this study. 72.6% of them report menstrual pain, with 45.9% requiring medication. 35.9% identify their menstrual bleeding as intense or very intense. 38.8% assert that menstrual discomforts affect their everyday life. 34.3% would have required not attending their work activities or having requested sick leave due to the discomforts, although only 17.3% of the women finally requested so, mainly because 58.4% considered that it might imply consequences in their professional environment, especially those with Higher Education. The women that report more discomforts are the youngest ones and those that resort to condoms as contraceptive method (p < 0.001).
Conclusions
Menstrual pain is a prevalent problem among women of reproductive age and can affect their everyday life and professional environment, requiring work leaves on some occasions.
Influence of eye movements on writing pressure during handwriting: A cross-sectional study
Authors: Suzuki Yumi , Fujii Hiromi 
Published: August 2023

Abstract
We are searching for a method to obtain stable writing pressure in patients with hemiplegia. So, this study aimed to investigate whether eye movements are involved in writing pressure during handwriting by healthy participants. A total of 28 healthy adults (2 men and 26 women, average age: 21.8 ± 0.6 years) were included in this study. The task was to draw 10 cm lines from left to right and from right to left 20 times. SensoMotoric Instruments Eye Tracking Glasses (SMI ETG) and an upper limb coordination evaluation system (TraceCoder, SYSNET Co. Ltd.) were used. Based on eye movement data, the participants were classified into “target locking type,” including those who kept looking at the goal from the start, and “close pursuit type,” including those who kept their eyes on the tip of the pen. The average writing pressure and change in the writing pressure per unit of time value were analyzed. The results showed that the amount of change in the writing pressure per unit of time value fluctuated greatly in the target locking type and was small in the close pursuit type. These findings suggest that eye movements affect writing pressure during line drawing.
Cryptocurrencies-tax evasion nexus: Does economic performance matter? The case of G-7 countries
Authors: Nawaz Allah Ditta , Bhutto Niaz Ahmed , Khan Shabeer 
Published: August 2023

Abstract
The global challenge of tax evasion presents a profound impact, leading to diminished tax revenues that are the lifeblood of a nation's seamless operations. This issue is exacerbated by the ingenious strategies employed by tax evaders, which distort economic performance benchmarks and create financial imbalances. Amidst these concerns, cryptocurrencies have emerged as a contentious subject, accused of abetting tax evasion. The covert nature of cryptocurrency transactions poses a significant hurdle for regulatory oversight and transaction recording. In response to this burgeoning concern, our comprehensive study delves into the intricate interplay between cryptocurrencies and tax evasion, utilizing annual data spanning from 2013 to 2020. With an extensive scope testing thirty two hypotheses and twelve interaction terms, our research unfurls the multifaceted dynamics at play. This study embarks by constructing a latest tax evasion index for the esteemed G-7 nations. Employing asymmetric/symmetric panel techniques, our investigation unveils a compelling revelation: cryptocurrencies exert a counteractive influence on instances of tax evasion. Furthermore, the nexus between economic performance and cryptocurrencies bears considerable sway over their correlation with tax evasion. Innovatively, our research charts the intricate relationship between tax evasion and cryptocurrencies across varying levels of economic performance. Notably, our findings underscore that Economic Freedom, Government Integrity, Government Spending, Business Freedom, Labor Freedom, Monetary Freedom, Investment Freedom, and Bureaucracy function as moderators, influencing the association between tax evasion and cryptocurrencies. These insights transcend academia, delivering significant implications to policymakers with informed guidance to devise nuanced strategies and policies.
Peripherally inserted central catheters can be an alternative to tunneled central venous catheters in chemotherapy for hematological and oncological pediatric patients
Authors: Kamata Yuko , Mizuno Yuki , Okamoto Kentaro , Okamoto Shota , Ito Yoshifumi , Nishigata Aya 
Published: August 2023

Abstract
Purpose
Tunneled central venous catheters (TCVs) are commonly used for pediatric chemotherapy. Recently, peripherally inserted central catheters (PICCs) have been used instead. Although PICC has the advantages of simpler insertion and fewer severe complications, there is little information on the efficacy of PICC compared to TCV in pediatric chemotherapy.
Methods
Patients, aged younger than 18 years, with primary malignancy who received chemotherapy with PICC or TCV at our institution from December 2007 to August 2022 were included in the study. We retrospectively compared PICC and TCV using medical records.
Results
Within the observation period, 133 catheters (73 PICCs and 60 TCVs) were inserted. The median indwelling time was 99 days for PICCs and 182 days for TCVs, with TCVs being significantly longer (p < 0.001). There were no significant differences in the incidence of complications, such as infections, thrombosis, obstruction, or mechanical accidents. Comparing patients treated with PICC (PICC group) versus those with TCV (TCV group), the time from diagnosis to insertion was significantly shorter in the PICC group (p < 0.001). In the PICC group, none of the patients required general anesthesia, and chemotherapy was completed with PICC only.
Conclusion
PICC can be an alternative to TCV in pediatric chemotherapy. (197 words)
Safety evaluation of a stepwise tracheostomy decannulation program in pediatric patients
Authors: Obayashi Juma , Fukumoto Koji , Yamoto Masaya , Miyake Hiromu , Nomura Akiyoshi , Kanai Risa , Nemoto Yuri , Tsukui Takafumi 
Published: August 2023

Abstract
Purpose In the event of failed tracheostomy decannulation, patients might have a tragic course of events. We retrospectively evaluated our stepwise tracheostomy decannulation program and examined its safety.Methods A 12-year retrospective study of pediatric patients was conducted. The decannulation program was performed on patients who had airway patency by laryngobronchoscopy and whose cannula could be capped during the day. A stepwise decannulation program was performed: continuous 48-hour capping trial during hospitalization (Phase 1), removal of the tracheostomy tube for 48 hours during hospitalization (Phase 2), and outpatient observation (Phase 3). If a persistent tracheocutaneous fistula existed, the fistula was closed by surgery (Phase 4).Results The 77 patients in the study underwent 86 trials. The age at the first time of the decannulation program was 6.5 ± 3.6 years old. Sixteen trials failed (18.6%): 8 trials in Phase 1, 2 trials in Phase 2, 4 trials in Phase 3, and 2 trials in Phase 4. Most decannulation failures were due to desaturation in Phase 1/2 and dyspnea in Phase 3/4. The time to reintubation after decannulation was 15–383 days in Phase 3/4.Conclusions Patients could fail at every phase of the program, suggesting that a stepwise decannulation program contributes to safety.
Kaistella yananensis sp. nov., a novel indoleacetic acid producing bacterium isolated from the root nodules of Sophora davidii (Franch.) Skeels
Authors: Ai Jiamin , He Xiaolong , Ren Mingxia , Yu Tianfei , Liu Xiaodong , Jiang Yingying , Li Zhefei , Deng Zhenshan 
Published: August 2023

Abstract
A novel endophytic bacterium named BT6-1-3T was isolated from the root nodules of Sophora davidii (Franch.) Skeels growing in Yan’an, Shaanxi Province, China. Cells were Gram-staining-negative, non-motile, oxidase-positive, catalase-positive and did not produce H2S. Strain BT6-1-3T grew at 15–40℃ (optimum 30℃), at pH 6.0–10.0 (optimum pH 9.0) and with 0–1% (w/v) NaCl (optimum 0.5%). The quinone system was menaquinone 6. The major fatty acids present in BT6-1-3T were iso-C11:0, iso-C15:0 and C16:0. The G + C content of genomic DNA was 39.35 mol% by whole genome sequencing. According to the analysis of 16S rRNA gene sequence, the closest relative was Kaistella montana WG4 (97.57%). The genome similarity was calculated using average nucleotide identity and genome-to-genome distance analysis. Both strongly supported that the strain BT6-1-3T belonged to the genus Kaistella as a representative of a new species. Based on phylogenetic analysis, chemotaxonomic data and physiological and biochemical characteristics, strain BT6-1-3T represents a new species of the genus Kaistella and is named as Kaistella yananensis sp. nov. Type strain is BT6-1-3T (= NBRC 115452T = CGMCC 1.60032T).
Hierarchical spatial interactions in the Aveiro-Ílhavo housing market
Retrieving W from data under an asymmetrical assumption
Authors: Batista Paulo , Bhattacharjee Arnab , Marques João , Wolf Jan , Castro Eduardo 
Published: August 2023

Abstract

Space is an important element for understanding housing values: it assimilates the complexity of locational preferences and translates them through market price dynamics. In housing price modeling, space tends to be incorporated through the lens of spatial heterogeneity and spatial dependence, which need to be explicitly modeled. The scientific debate on the field has been encouraging more relaxed assumptions regarding the specification of socio-economic-spatial relations, with a data-driven (ex-post) W specification gaining importance over the years. This work draws from theoretical and empirical insights on spatial diffusion, particularly the so-called ripple effects in housing market prices, combining them with an approach to estimate W from data. It applies a strategy to retrieve a spatial dependence structure under the minimal assumption that they are hierarchical, using a Monte Carlo simulation and an empirical application to a local housing market in Portugal (Aveiro-Ílhavo). It shows this technique's feasibility in producing estimates of spatial dependence at the local scale to identify complex but meaningful territorial interaction structures. The revealed spatial interactions are compatible with the notion of ripple effects and also surpass geographical proximity.
General Purpose Propofol Target Controlled Infusions Using the Marsh Model with Adjusted Body Weight
Authors: Zhong George , Xu Xiabing 
Published: August 2023

Abstract
Purpose
We report a novel method for adjusting the input weight of the Marsh target controlled infusion (TCI) model so that it mimics the behavior of the Eleveld model. In this study, we compare the performance of our weight adjusted Marsh model with the Eleveld model across diverse patient groups.
Methods
We simulated 2,768 subjects with diverse combinations of age, weight, height and sex undergoing a hypothetical four-hour propofol TCI with either the Eleveld model or the Marsh model using our adjusted input weight. The performance of our augmented Marsh model was compared with the Eleveld model using established methods.
Results
The Marsh model using our adjusted weight input produced infusion regimes and effect site concentrations closely mimicking that of the Eleveld model for all simulated patients. The median and maximum absolute performance errors of our augmented Marsh model were less than 8.1% and 20.3%, respectively, compared to the Eleveld model.
Conclusion
By adjusting the input weight using our novel algorithm, the infusion regime of the Marsh model produced effect site concentrations closely mimicking that of the Eleveld model. We believe this is a robust way of improving the precision of the Marsh model, especially in patients at extremes of age and body mass index, until the Eleveld model becomes more widely available in commercial infusion pumps.
Accuracy of the I2 point estimate for testing selection bias risk in meta-analyses – a simulation study (Protocol)
Authors: Mickenautsch Steffen , Yengopal Veerasamy 
Published: August 2023

Abstract
Objectives: To establish the test sensitivity and specificity of the I2 point estimate for testing selection bias risk in meta-analyses under condition of large versus small trial sample size and large versus small trial number in meta-analysis and to test the null-hypothesis that the differences are not statistically significant.

Methods: Simulation trials will be generated in MS Excel, each consisting of three components, entered in form of three parallel columns: a sequence of subject ID (accession) numbers representing trial subjects; a random sequence of allocation to group A or B and a random sequence of a simulated baseline variable (‘age’) per subject, ranging between 50 to 55. These simulation trials will be included into five types of meta-analyses with large/small numbers of trials, as well as trials with large and small sample sizes. All meta-analyses will be tested using the I2 point estimate. The numbers of true positive, false positive, false negative and true negative test results will be established. From these, the test sensitivity and specificity will be computed for each of the meta-analysis types and statistically compared.

Ethics and dissemination: Ethical approval is not required for simulation-based studies. The results will be disseminated as a prior preprint version and subsequent peer-reviewed publication.
On The Physics of Glaciations and Lessons Learned
Authors: Swedan Nabil 
Published: August 2023

Abstract

Fossil fuel reserves will ultimately be depleted, and carbon neutral or low carbon economies of the future may restore past climate regulating parameters. Therefore, knowledge of the physics of glaciations and paleoclimates is warranted. Glaciations occurred when the atmosphere was rich in carbon dioxide. They were initiated by the instinctive and inherent tendency of living matter to multiply. When the size of aquatic photosynthesis increased, chemical energy was stored in plant tissues, and the surrounding sea water lost an equal amount of heat. The decrease in sea temperature was small; however, it was amplified by the ocean. Aquatic photosynthesis is a thermodynamic cycle and requires a flow of sea water medium of heat transfer. The flow of water alters the thermohaline circulation pattern. As a result, during cooling periods, cold water of the deep ocean was displaced to the surface, and surface cooling was amplified. The opposite occurred during warming periods. The cold water was returned back to the deep ocean. Accordingly, past surface temperature variation is calculated and found to be in agreement with observations. Based on this understanding, reducing carbon dioxide in the atmosphere to 350 ppmv is unnecessary, and artificial sequestration of carbon dioxide is unjustified.
NiTiHfX Shape Memory Alloy Actuation Strain Prediction
Authors: Abedi Hossein , Qattawi Ala 
Published: August 2023

Abstract
Data-driven techniques are used to predict the actuation strain (AS) of NiTiHfX shape memory alloy (SMA). A Machine Learning (ML) approach is used to overcome the high dimensional dependency of NiTiHfX AS on numerous factors, as well as the lack of fully known governing physics. Detailed data extraction on available experimental studies is performed to gather any related information about the actuation strain. The elemental composition, manufacturing approaches, thermal treatments, applied stress, and post-processing steps that are commonly used to process NiTiHfX and have an impact on the material AS are used as input parameters of the ML models.
Since a broad data collection is performed the information for each input factor was sufficient for the use of the majority of the accessible information in the literature on NiTiHfX AS. Taking into account most of the regular NiTiHfX processing factors also enables the option of tuning additional characteristics of NiTiHfX in addition to the ASs. The work is unique as is the first to fully investigate the NiTiHfX AS prediction.
To forecast the NiTiHfX ASs, a total of 901 data sets or 17119 data points were gathered, verified, and selected. Several machine-learning approaches were applied and joint to gather to guarantee robust modeling. The global model's overall determination factor (R2) was 0.96, suggesting the viability of the proposed NN model. Such a model opens the possibility of intelligent material selection and processing to maximize the AS or shape memory effect of NiTiHf SMA.
Internal Ribosome Entry Sites act as Effector Domain in linear and circular antisense long non-coding SINEUP RNAs.
Authors: D’Agostino Sabrina , Tettey-Matey Abraham , Volpe Massimiliano , Pierattini Bianca , Ansaloni Federico , Lau Pierre , Bon Carlotta , Peruzzo Omar , Braccia Clarissa , Armirotti Andrea , Scarpato Margherita , Damiani Devid , Carlo Valerio Di , Broglia Laura , Bechara Elias , Tartaglia Gian Gaetano , Carninci Piero , Santoro Claudio , Persichetti Francesca , Pandolfini Luca , Espinoza Stefano , Zucchelli Silvia , Sanges Remo , Gustincich Stefano 
Published: August 2023

Abstract
SINEUPs are antisense long non-coding RNAs that enhance translation of overlapping sense mRNAs through the activity of two domains: a SINEB2 sequence UP-regulating translation (Effector Domain, ED) and an antisense region providing target specificity (Binding Domain, BD).
In this study, we demonstrate that the invSINEB2 sequence from the natural SINEUP AS Uchl1 RNA is an Internal Ribosomal Entry Site (IRES) when acting in cis and that known viral and cellular IRES sequences can act as Effector Domain in synthetic SINEUPs.
To identify natural IRES-containing, non-coding RNAs with SINEUP-like activity, we focused on circular RNAs showing that the non-coding hsa_circ_0085533 (circMyc), transcribed from the c-myc locus, enhances endogenous protein expression of its target PX Domain Containing Serine/Threonine Kinase Like (Pxk) by increasing mRNA association to polysomes.
In summary, this study shows that natural and synthetic SINEUPs include linear and circular transcripts with an embedded IRES sequence as ED.
PENGARUH LINGKUNGAN KERJA DAN KETERIKATAN KARYAWAN TERHADAP KINERJA KARYAWAN HOTEL DI KOTA YOGYAKARTA
Authors: Daulay Geby Silvia Meylani , Respati Agustini Dyah 
Published: August 2023

ABSTRAKPenelitian ini bertujuan untuk untuk menguji pengaruh lingkungan kerja dan keterikatan karyawan terhadap kinerja karyawan beberapa hotel di Kota Yogyakarta. Data penelitian dikumpulkan melalui kuesioner hardcopy yang dibagikan secara langsung dengan mendatangi tiap-tiap hotel tempat responden bekerja. Hotel-hotel tersebut meliputi delapan hotel dengan kriteria Bintang 2 dan Bintang 3 di kota Yogyakarta yaitu hotel D’kayon, hotel Orlen, De Laxton hotel, Puri Artha hotel, Grand Kangen hotel Urip Sumoharjo, Tickle hotel, Favehotel Kusumanegara dan Grand Puri Saron Hotel dengan total sebanyak 80 responden. Data penelitian diolah dengan bantuan program SPSS (Statistical Program for Social Science). Sampel dipilih menggunakan simple random sampling, yang dilakukan secara acak tanpa mempertimbangkan strata yang ada di dalamnya. Hasil uji analisis linier berganda dan uji t menunjukkan bahwa variabel lingkungan kerja tidak berpengaruh terhadap kinerja karyawan; sedangkan keterikatan karyawan berpengaruh terhadap kinerja karyawan.Kata Kunci: Lingkungan Kerja; Keterikatan Karyawan; Kinerja Karyawan Hotel ABSTRACTThe purpose of this study was to determine the influence of work environment and employee engagement on the performance of hotel employees in Yogyakarta City. The research data was obtained through a hardcopy questionnaire that was shared directly by visiting each hotel. The hotels used in this study included 8 hotels from 2 and 3 stars in the city of Yogyakarta, namely D'kayon hotel, Orlen hotel, De Laxton hotel, Puri Artha hotel, Grand Kangen hotel Urip Sumoharjo, Tickle hotel, Favehotel Kusumanegara and Grand Puri Saron Hotel with a total of 80 respondents. Then it is processed using the SPSS (Statistical Program for Social Science). Sampling is selected using simple random which is done randomly without considering the strata in it. The test results using multiple linear analysis and t test with the results of the work environment have no effect on employee performance while employee attachment affects employee performance.Keywords: Work Environment; Employee Engagement; Hotel Employee Performance