bluuebunny/crossref_metadata_2025_split huggingface dataset:
The journey of F1000Research since inception: through bibliometric analysis
Authors: Kumar Dilip , Shandilya Abhinav Kumar , Srivastava Sandeep 
Published: June 2023

Background: Bibliometric analysis is an approach adopted by researchers to understand the various analytics such as year-wise publications, their citations, most impactful authors and their contributions, identification of emerging keywords, multiple themes (niche, motor, basic, and emerging or declining) etc. F1000Research is one of the Q1 category journals that publishes articles in various domains, but a detailed journal analysis is yet to be done. Methods: This study is an effort to extract the F1000Research journey information through bibliometric analysis using VOS-viewer and Biblioshiny (R-studio) interface. The F1000Research journal started its journey in 2012; since then, 5767 articles have been published until the end of 2022. Most of the published articles are from medical science, covering Biochemistry, Genetics & Molecular Biology, Immunology & Pharmacology, Toxicology & Pharmaceutics. To understand the research journey, various analyses such as publication & citation trends, leading authors, institutions, countries, most frequent keywords, bibliographic coupling between authors, countries and documents, emerging research themes, and trending keywords were performed. Results: The United States is the biggest contributor, and COVID-19 is the most commonly occurred keyword. Conclusions: The present study may help future researchers to understand the emerging medical science domain. It will also help the editors and journal to focus more on developing or emerging areas and to understand their importance towards society. Future researchers can contribute their quality research studies, focusing on emerging themes. These authors’ research can guide future researchers to develop their research area around the most impacted articles. They can collaborate with them to bring that emerging theme forward.
impact of ultraviolet radiation on the skin and the role of photoprotection – the review of the literature
Authors: Antonik Dominika , Denys Barbara , Góra Karolina , Zdziennicki Wojciech , Zimnicki Patryk , Lato Marta , Iberszer Konrad , Litwiniuk Maria , Zaniuk Marcin , Hurkała Kamil 
Published: June 2023

Introduction and objective:
The sun emits ultraviolet radiation in the UV-A, UV-B and UV-C ranges. Photoprotection is used to prevent the impact of this radiation on the skin. It effectively counteracts photoaging, photodermatoses and photocarcinogenesis.
The aim of the study is to discuss the impact of UV radiation on the skin and the role of sun protection, also in special groups of patients - children and non-immunocompetent people. The article also presents a summary of data on the effect of sunscreens on vitamin D synthesis.
Materials and methods:
The literature was reviewed in the Pubmed, Google Scholar database and in the recommendations of the Polish Dermatological Society with the use of keywords.
State of knowledge:
Erythema is the most visible effect of sunburn, but exposure to UV radiation is primarily photocarcinogenesis or photoimmunosuppression. The SPF factor is the main determinant of the effectiveness of sunscreens, but effective protection against both UVB and UVA radiation is essential. Daily use of sunscreen reduces skin damage associated with exposure to light and does not negatively affect vitamin D synthesis.
Conclusions:
The basis of skin protection is using sunscreens, avoiding excessive exposure to solar radiation and using protective clothing, hats and sunglasses. Thanks to these activities, we can significantly reduce the number of cases of certain skin cancers. It is also important to remember that sun protection applies to everyone, especially children and non-immunocompetent people.
Intermittent fasting – a novel approach to treating overweight and obesity? – meta-analysis and literature review
Authors: Lubczyńska Zuzanna , Popravko Yevheniia , Lewandowski Mateusz Mirosław , Bienia Grzegorz , Żołnierek Maja , Świętochowski Jakub , Siekierko Nikola , Kotusiewicz Wiktoria , Jędrzejewska Barbara , Kotulska Maria 
Published: June 2023

Introduction Intermittent fasting (IF) is a form of dietary intervention that includes periods of regular calorie intake alternated with periods of fasting. IF has gained a lot of attention as a potential approach to treating metabolic syndrome-related diseases. Therefore, health care professionals need to be able to provide their patients with evidence-based information on IF. The aim of this article is to review data on effectiveness of IF in weight loss, especially in comparison with calorie restriction.
MethodsPubMed and Google Scholar databases were searched for studies published from 1.01.2017 to 31.12.2022 that included phrases “intermittent fasting” or “alternate day fasting”, “intermittent fasting obesity”, “alternate day fasting obesity”. Intervention studies on obese or overweight patients were included. We excluded studies of short duration and studies that focused on intercurrent medical conditions. In total, 14 articles that suited those criteria were identified.
ResultsIntermittent fasting induces pronounced metabolic changes in the body due to strict and time-limited restriction of calorie intake and in animal models was proved to prolong lifespan and modulate tumorigenesis and aging. It is a proposed new approach to treating obesity, which is a a major risk factor for cardiovascular diseases and diabetes.
ConclusionsIn our study, IF was found as effective, but not superior to calorie restriction in reducing body mass, improving body composition and reducing other cardiometabolic risk factors. Our findings are consistent with other recent systematic reviews. Further research is needed to directly compare various IF regimens and determine patients’ characteristics that may be associated with more successful implementation of intermittent fasting regimens.
İLK TÜR NEOLİTİK ÇÖMLEKÇİLİKTEN ÜÇ BOYUTLU YAZICILARLA SERAMİK ÜRETİMİNE
Authors: ÜNAL Serap , HASEKİOĞLU Uygar 
Published: June 2023

Birinci tür çömlekçilik olarak adlandırılan, elle şekillendirmede yaygın olarak kullanılan, formu fitil tekniği ile yükselterek oluşturma yöntemi, günümüzde de aynı zamanda önemli bir kültürel değer olarak sürdürülmektedir. Bu tarz üretimin ilk ustasının günümüzden 50-60 milyon yıl önce varlığı ön görülen çömlekçi yaban arısı olduğu da göz ardı edilmemelidir. Aynı zamanda bu yöntem çağdaş teknolojilere de esin vermiştir. Üç boyutlu yazıcılarda polimer ve toprak malzemelerle üretilen formların teknolojik temelde çıkış noktası birinci tür ilkel çömlekçiliktir. Çömlek üretiminin makine destekli gelişimi; çarklı çömlekçilikten itibaren, günümüzün inovatif üretim teknolojileri arasında önemli bir yer tutan 3B bilgisayar destekli yazıcılarla yapılan üretim tarzına ve daha da ileriye dönük bir gelişim içinde Delta Wasp sistemiyle mimaride konut yapımına kadar taşınmıştır.
Çalışmada, yaklaşık 9000 yıllık pişmiş toprak üretimi ve kültürü olan çömlekçiliğin değerli bir maddi kültür unsuru olduğu vurgulanmış, çağdaş seramik endüstrisi ve sanatına ilham veren yansımaları incelenmiş, anılan biyomimetik ve tarihsel aktarımla birlikte, 3B yazıcılarla Göller Bölgesi killeri ile Tekstür profil analizi (TPA) yapılarak seramik üretimi ve uygulamaları hakkında bilgi üretilmesi amaçlanmıştır.
Anahtar kelimeler: Çömlekçilik, Kültürel Miras, 3B Seramik Üretimi, Tekstür profil analizi.
IgG4 antibodies to the recombinant filarial antigen Wb-Bhp-1 decrease dramatically following treatment of lymphatic filariasis
Authors: Greene Sarah E. , Huang Yuefang , Curtis Kurt C. , King Christopher L. , Fischer Peter U. , Weil Gary J. 
Published: June 2023

Background
Lymphatic filariasis (LF) is a neglected tropical disease and a major cause of chronic disability. Improved diagnostic tests are needed because of long-term persistence of anti-filarial antibodies or circulating filarial antigenemia after treatments that clear microfilaremia. Here, we assess changes in levels of antibodies to the recombinant filarial antigens Wb-Bhp-1, Wb123, and Bm14 after anti-filarial treatment.

Methodology/principal findings
IgG4 antibodies to recombinant filarial antigens were assessed by ELISA. We tested serial plasma samples from a clinical trial in Papua New Guinea. Before treatment, 90%, 71% and 99% of participants had antibodies to Wb-Bhp-1, Wb123, and Bm14, respectively. Antibodies to Wb-Bhp-1 and Wb123, but not Bm14, were significantly higher in participants with persistent microfilaremia 24 months after treatment. Antibodies to all three antigens declined significantly by 60 months after treatment with ivermectin, diethylcarbamazine and albendazole despite circulating filarial antigen in 76% of participants. By 60 months follow up, antibodies to Wb-Bhp-1, Wb123, and Bm14 were detected in 17%, 7% and 90% of participants, respectively. Antibodies to Wb-Bhp-1 also declined more rapidly after treatment than antibodies to Bm14 in samples from a clinical trial conducted in Sri Lanka. We also tested archived serum samples from people living in filariasis-endemic communities in Egypt with different infection profiles. Antibodies to Wb-Bhp-1 were detected in 73% of microfilaremic people, 53% of amicrofilaremic people with circulating filarial antigen, and 17.5% of endemic individuals without microfilaria or circulating filarial antigen. Tests performed with legacy samples from India showed that few people with filarial lymphedema had antibodies to these recombinant antigens.

Conclusions
Antibodies to Wb-Bhp-1 and Wb123 are more closely correlated with persistent microfilaremia than circulating filarial antigenemia or antibodies to Bm14, and they clear more rapidly after anti-filarial treatment. Additional studies are needed to assess the value of Wb-Bhp-1 serology as a tool for determining the success of LF elimination efforts.
Code Stroke Postendoscopy: A Case of Pneumocephalus From a Spinal-Esophageal Fistula
Authors: Fetz Andrew , Ghaseminejad Farhad , Kim Hyun Jae , Gan S. Ian 
Published: June 2023

ABSTRACT
Esophageal fistula to the respiratory tract and mediastinum is a well-described complication from esophageal malignancies. Spinal-esophageal fistula (SEF) on the other hand is a much rarer complication that has only been reported in few instances. Here, we report a unique case of fatal spinal-esophageal fistula with an associated pneumocephalus in an 83-year-old woman with metastatic esophageal squamous cell carcinoma.
Miliary Tuberculosis in a Patient With Ulcerative Colitis Treated With Tofacitinib
Authors: Verma Shruti , Singh Arshdeep , Kakkar Chandan , Tripathi Ashish , Midha Vandana , Sood Ajit 
Published: June 2023

ABSTRACT
Immunosuppression with tumor necrosis factor-alpha inhibitors and tofacitinib is a risk factor for reactivation of latent tuberculosis (TB) and the development of active TB. We report a case of miliary TB in a patient on treatment with tofacitinib for active ulcerative colitis. By week 4 of therapy, a clinical response was achieved. Subsequently, although being on treatment, the patient started having fever with night sweats and myalgias. The investigative workup revealed pulmonary miliary TB. Tofacitinib was withdrawn, and antitubercular therapy was initiated. The patient responded, both clinically and radiologically, to the antitubercular therapy. This case report highlights the importance of screening for latent TB in patients receiving tofacitinib.
Weight Loss Success With Repeat Intragastric Balloon Placement After Hyperinflation and Removal of the Index Balloon
Authors: Craig Michael A. , Kay Carl L. , Stilwell Kendra T. , Quiles John G. 
Published: June 2023

ABSTRACT
Intragastric balloons are an increasingly common endoscopic alternative to bariatric surgery for the treatment of obesity. Hyperinflation is a rare complication that presents as acute-onset epigastric pain, nausea, vomiting, early satiety, abdominal distention or bloating, and rapid weight loss. Hyperinflation requires prompt diagnosis and removal of the balloon to prevent complications including gastric outlet obstruction or gastric perforation. We present a case of intragastric balloon hyperinflation with removal of the index device, followed by replacement with a second balloon, resulting in continued weight loss without further adverse events.
Investigation of the relationship between functional movement screening scores and hamstring muscle strength in professional football players
Authors: İbiş Serkan , Kurt Songül , Aka Hasan , Oszlánczi Adrienn 
Published: June 2023

The aim of this study is to examine the relationship between hamstring (H) muscle strength (peak muscle strength, average muscle strength and bilateral muscle strength differences between both legs) and Functional Movement Screening (FMS) test scores of professional football players. 14 professional male football players (age: 21.50±2.47) voluntarily participated in the study. Functional movement patterns of football players FMS test with the t kit, H muscle strength was determined with the H Board device. Spearman correlation analysis was used to determine the relationship between participants' H muscle strength and FMS test scores. While it was determined that the FMS total score of the football players was above the critical limit of 14 points in determining the injury risk, no relationship was found between the FMS total scores and the H muscle strength (p>0.05). As a result, there was a significant correlation between the FMS subtests (deep squatting, obstacle stepping, single line lunge and active straight leg lifting) and total scores of professional football players and the peak muscle strength, mean muscle strength and bilateral muscle strength differences between both legs of the H muscle group. No relationship was found. In the estimation of injuries according to FMS test scores, it may be recommended to evaluate the hip, knee and ankle flexor and extensor muscle groups in addition to the H muscle group and look at the relationship between them.
Extended English summary is in the end of Full Text PDF (TURKISH) file.
Özet
Bu çalışmanın amacı, profesyonel futbolcuların hamstring (H) kas kuvveti (zirve kas kuvveti, ortalama kas kuvveti ve her iki bacak arasındaki bilateral kas kuvvet farkları) ile Fonksiyonel Hareket Taraması (FHT) test skorları arasındaki ilişkinin incelenmesidir. Çalışmaya gönüllü 14 profesyonel erkek futbolcu (yaş: 21,50±2,47) katılmıştır. Futbolcuların fonksiyonel hareket kalıpları FHT test kiti ile, H kas kuvveti H Board cihazı ile belirlenmiştir. Katılımcıların H kas kuvveti ile FHT test skorları arasındaki ilişkiyi belirlemede Spearman korelasyon analizi kullanılmıştır. Futbolcuların FHT toplam skorunun yaralanma riskini belirlemede kritik sınır olan 14 puanın üstünde olduğu belirlenirken, FHT toplam skorları ile H kas kuvveti arasında ilişki tespit edilmemiştir (p>0,05). Sonuç olarak profesyonel futbolcuların FHT alt testleri (derin çömelme, engel adımlama, tek çizgide hamle ve aktif düz bacak kaldırma) ve toplam skorları ile H kas grubuna ait zirve kas kuvveti, ortalama kas kuvveti ve her iki bacak arasındaki bilateral kas kuvvet farkları arasında anlamlı bir ilişki olmadığı bulunmuştur. FHT test skorlarına göre yaralanmaların tahmin edilmesinde H kas grubuna ilaveten kalça, diz ve ayak bileği fleksör ve ekstensör kas gruplarının da değerlendirilerek arasındaki ilişkiye bakılması önerilebilir.
Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection
Authors: Krčmová Lenka Kujovská , Matoušová Kateřina , Javorská Lenka , Šmahel Petr , Skála Mikuláš , Koblížek Vladimír , Škop Jan , Turoňová Dorota , Gančarčíková Markéta , Melichar Bohuslav 
Published: June 2023

Abstract

Objectives
Currently, no biomarker or scoring system could clearly identify patients at risk of progression to a severe coronavirus disease (COVID)-19. Even in patients with known risk factors, the fulminant course cannot be predicted with certainty. Analysis of commonly determined clinical parameters (frailty score, age, or body mass index) together with routine biomarkers of host response (C-reactive protein and viral nucleocapsid protein) in combination with new biomarkers neopterin, kynurenine, and tryptophan, could aid in predicting the patient outcome.

Methods
In 2021 and 2022, urine and serum samples were prospectively collected on 1st to 4th day after hospital admission in 108 consecutive COVID-19 patients hospitalized at the University Hospital Hradec Králové, Czech Republic. Delta and omicron virus variants were studied. Neopterin, kynurenine and tryptophan were determined by liquid chromatography.

Results
A significant correlation was observed between urinary and serum biomarker concentrations. Urinary and serum neopterin, kynurenine and kynurenine/tryptophan ratio were significantly (p≤0.05) higher in patients who subsequently needed oxygen therapy vs. patients without oxygen therapy. These parameters were also significantly increased in patients who died during the hospitalization compared to survivors. Complex equations have been derived using the investigated biomarkers and other clinical or laboratory parameters to predict the risk of subsequent oxygen therapy or death during hospitalization.

Conclusions
Present data demonstrate that neopterin, kynurenine and kynurenine/tryptophan ratio in the serum or in the urine represent promising biomarkers in the management of COVID-19 that may help to guide important therapeutic decisions.
Does the Free Group Agency Account of Legitimacy Require Democracy?
Authors: Bech-Pedersen Palle , Haberkost Finn 
Published: June 2023

Abstract
In this critical comment, we argue that nondemocratic, but decent regimes fail to constitute legitimate governance under Applbaum’s free group agency account. To make this case, we first introduce the three principles of liberty, equality and agency that Applbaum takes to flow directly from his free agency conception of legitimacy. Against this backdrop, we discuss Applbaum’s claim that a nondemocratic regime along the lines of a Rawlsian decent consultation hierarchy could meet the threshold of legitimacy. Contrary to this suggestion, we argue that nondemocratic, but decent regimes cannot claim legitimacy under Applbaum’s account because they are constitutively inegalitarian, thus failing to adequately grant citizens the equal normative power without which legitimacy is unattainable under the free group agency account.
Arms race between anti‐silencing and RdDM in noncoding regions of transposable elements
Authors: Sasaki Taku , Kato Kae , Hosaka Aoi , Fu Yu , Toyoda Atsushi , Fujiyama Asao , Tarutani Yoshiaki , Kakutani Tetsuji 
Published: June 2023

AbstractTransposable elements (TEs) are among the most dynamic parts of genomes. Since TEs are potentially deleterious, eukaryotes silence them through epigenetic mechanisms such as repressive histone modifications and DNA methylation. We previously reported that Arabidopsis TEs, called VANDALs, counteract epigenetic silencing through a group of sequence‐specific anti‐silencing proteins, VANCs. VANC proteins bind to noncoding regions of specific VANDAL copies and induce loss of silent chromatin marks. The VANC‐target regions form tandem repeats, which diverge rapidly. Sequence‐specific anti‐silencing allows these TEs to proliferate with minimum host damage. Here, we show that RNA‐directed DNA methylation (RdDM) efficiently targets noncoding regions of VANDAL TEs to silence them de novo. Thus, escape from RdDM could be a primary event leading to the rapid evolution and diversification of sequence‐specific anti‐silencing systems. We propose that this selfish behavior of TEs paradoxically could make them diverse and less harmful to the host.
AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway
Authors: Cheng Yalan , Zhang Zhentong , Gao Peidong , Lai Hejin , Zhong Wuling , Feng Ning , Yang Yale , Yu Huimin , Zhang Yali , Han Yumo , Dong Jieya , He Zhishui , Huang Rui , Zhai Qiwei 
Published: June 2023

AbstractObesity and diabetes are risk factors for hepatocellular carcinoma (HCC); however, the underlying mechanisms are yet to be elucidated. Adeno‐associated virus (AAV) frequently infects humans and has been widely used in gene therapy, but the risk of AAV infection such as HCC should be further evaluated. Here, we show that recombinant AAV injection caused liver injury, hepatic necroptosis, and HCC in db/db or high‐fat diet‐induced hyperglycemic and obese mice, but not in mice with only hyperglycemia or obesity. Prednisone administration or knockdown of Pebp1, highly expressed in db/db mice, alleviated hepatic injury and necroptosis induced by recombinant AAV in mice with diabetes and obesity. Inhibition of Pebp1 pathway also attenuated inflammation and necroptosis in vitro. Our findings show that AAV infection is a critical risk factor for HCC in patients with diabetes and obesity, and AAV gene therapy for these patients should be carefully evaluated. Both prednisone treatment and targeting Pebp1 pathway are promising strategies to alleviate inflammation and necroptosis that occurred in AAV gene therapy or related diseases.
Interference, explicitation, implicitation and normalization in third code Spanish: Evidence from discourse markers
Authors: Rabadán Rosa , Gutiérrez-Lanza Camino 
Published: June 2023

AbstractThird code research has documented the distinctiveness of translated language and singled out recurrent tendencies framing them as translation universals. This paper aims to identify the interaction between interference, explicitation, implicitation and normalization and their potential relationship(s) with other variables, such as register. The focus of the study is on Spanish discourse markers (DMs) translated from English. This study uses interference, explicitation, implicitation and normalization as methodological tools to unveil these patterns. Evidence comes from a bilingual parallel corpus (P-ACTRES 2.0), a corpus of translated Spanish (CETRI), and a reference corpus of contemporary Spanish (CORPES XXI). We select the input DMs according to two criteria: first, we focus on DMs showing cross-linguistic formal correspondence, indicating the possibility of grammatical interference; second, we consider different procedural meanings for the DMs to anticipate potential regularity distortions. Results indicate that DM underuse in the target texts generally co-occurs with explicitation. Register is an important variable: implicitation is more frequent in non-fiction and, together with normalization, affects the majority of DMs. Evidence also points to the DMs' semantics influencing implicitation and explicitation.