bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pilot randomized clinical trial of virtual reality pain management during adult burn dressing changes: Lessons learned
Authors: Armstrong Megan , Coffey Rebecca , Luna John , Xiang Henry 
Published: September 2023

Opioids are the most frequently used pain medications by US burn centers to control severe procedural pain during wound care. Concerns for long-term opioid use have prompted the exploration of non-pharmaceutical interventions, such as virtual reality (VR), for procedural pain management. The primary objective of this pilot study was to evaluate the feasibility and efficacy of VR pain alleviation treatment in reducing adult burn patients’ perceived pain during burn dressing changes. Adult patients aged 18–70 years were recruited from the inpatient unit of a single American Burn Association–verified burn center between May 2019 and February 2020 and randomly assigned to one of three arms. Active VR participants played four VR games; passive VR participants were immersed in the same VR environment without the interaction elements; and a standard of care control group. 71 patients were screened for eligibility and 33 were deemed eligible to approach for informed consent, with 14 agreeing to participate in this study. Of these 14 patients, 4 were randomly assigned to the active VR, 4 to the passive VR, and 6 to the control group. Self-reported overall pain was lowest among participants in the active VR (dressing 1 = 41.3, dressing 2 = 61.0, and dressing 3 = 72.7) and highest among participants in the passive VR (dressing 1 = 58.3, dressing 2 = 74.5, and dressing 3 = 89.0) across all three dressing changes. Self-reported worst pain was lowest among the active VR at the first and last dressing (64.3 and 92.2, respectively), but the control group has the lowest self-reported worst pain at the second dressing (71.3). VR is a useful non-pharmacological tool for pain distraction but designing and implementing clinical research studies face many challenges in real-world medical settings. Lessons from this study have important implications for future VR studies by other researchers.
Trial Registration: ClinicalTrials.gov Identifier: NCT04545229.
Posting patterns in peer online support forums and their associations with emotions and mood in bipolar disorder: Exploratory analysis
Authors: Jagfeld Glorianna , Lobban Fiona , Davies Robert , Boyd Ryan L. , Rayson Paul , Jones Steven 
Published: September 2023

Background
Mental health (MH) peer online forums offer robust support where internet access is common, but healthcare is not, e.g., in countries with under-resourced MH support, rural areas, and during pandemics. Despite their widespread use, little is known about who posts in such forums, and in what mood states. The discussion platform Reddit is ideally suited to study this as it hosts forums (subreddits) for MH and non-MH topics. In bipolar disorder (BD), where extreme mood states are core defining features, mood influences are particularly relevant.

Objectives
This exploratory study investigated posting patterns of Reddit users with a self-reported BD diagnosis and the associations between posting and emotions, specifically: 1) What proportion of the identified users posts in MH versus non-MH subreddits? 2) What differences exist in the emotions that they express in MH or non-MH subreddit posts? 3) How does mood differ between those users who post in MH subreddits compared to those who only post in non-MH subreddits?

Methods
Reddit users were automatically identified via self-reported BD diagnosis statements and all their 2005–2019 posts were downloaded. First, the percentages of users who posted only in MH (non-MH) subreddits were calculated. Second, affective vocabulary use was compared in MH versus non-MH subreddits by measuring the frequency of words associated with positive emotions, anxiety, sadness, anger, and first-person singular pronouns via the LIWC text analysis tool. Third, a logistic regression distinguished users who did versus did not post in MH subreddits, using the same LIWC variables (measured from users’ non-MH subreddit posts) as predictors, controlling for age, gender, active days, and mean posts/day.

Results
1) Two thirds of the identified 19,685 users with a self-reported BD diagnosis posted in both MH and non-MH subreddits. 2) Users who posted in both MH and non-MH subreddits exhibited less positive emotion but more anxiety and sadness and used more first-person singular pronouns in their MH subreddit posts. 3) Feminine gender, higher positive emotion, anxiety, and sadness were significantly associated with posting in MH subreddits.

Conclusions
Many Reddit users who disclose a BD diagnosis use a single account to discuss MH and other concerns. Future work should determine whether users exhibit more anxiety and sadness in their MH subreddit posts because they more readily post in MH subreddits when experiencing lower mood or because they feel more able to express negative emotions in these spaces. MH forums may reflect the views of people who experience more extreme mood (outside of MH subreddits) compared to people who do not post in MH subreddits. These findings can be useful for MH professionals to discuss online forums with their clients. For example, they may caution them that forums may underrepresent people living well with BD.
Preliminary efficacy of aerobic training among university students with migraine symptoms: Study protocol for a pilot randomized controlled trial
Authors: Selvakumar Kiruthika , Lee Fan Tan , Chai Nien Foo , Hou Kit Mun 
Published: September 2023

Background
Migraine is a primary neurological headache. Treatment of this condition includes medications; however, these medications, when given for a longer duration, can have side effects. If migraine is left untreated or undiagnosed, it is reported that around 2.5% of individuals with migraine may develop to have a chronic condition. This study aims to analyse the preliminary effectiveness of aerobic training on migraine pain level, sleep quality, quality of life, and resting-state brain waves among university students with migraine symptoms.

Methodology
88 university students with migraine symptoms are the target participants. 4 of 5 on the Migraine Screen Questionnaire, 5 of 7 on the International Classification of Headache Disorders 3rd edition (ICHD-3), and both genders aged 18–40 years will be included. The participants with a score of more than or equal to 5 on the visual aura rating scale, diagnosed with a secondary headache, pregnancy, medication for neurological and cardiorespiratory conditions, and unwilling to participate will be excluded. Based on the disability questionnaire, the participants will be randomly assigned to either of the three groups. The primary outcome is resting-state electroencephalography (EEG) brain, and the secondary outcomes are sleep quality, quality of life, and migraine pain level. The post-test assessments will be performed at week 6.

Result
After the primary EEG analysis using MATLAB, the amplitude, frequency, frequency band ratio, and power spectrum density will be analysed. Mixed design analysis and intention-to-treat analysis will be used to assess the efficacy of aerobic training.

Discussion
Migraines can be unpredictable, sometimes occurring without symptoms. If underdiagnosed or over-looked, it encompasses a serious of long-term effects. Hence with appropriate intervention, the symptoms can be prevented from worsening. But there is an unmet need for evidence-based non-pharmacological approaches to complement pharmacotherapy in migraine prevention. Moreover, an exercise intervention may be more suitable for people with migraine considering their tendency toward inactivity. Although some studies developed exercise programs for untrained patients with migraine, the outcome was primarily in terms of exercise capacity rather than the primary characteristics and secondary brain wave/ sleep quality changes, indicating the need for this study.
Recent Advances in Childhood Asthma
Authors: Sastroasmoro Sudigdo 
Published: September 2023

Research in bronchial asthma shows striking advances in the last fifteen years.
In recent years, advances in immunology and the introduction of beta adrenergic theory (neuro-humoral theory) lead to a new and comprehensive understanding on the pathogenesis and pathophysiology of asthma.
Physiological changes in asthma are particularly concerning the affection of smaller air ways, the goal of the newer methods is to find the most sensitive and reliable method to detect small airway alteration.
The current advances in the treatment of asthma are the sympathomimetic amines and the related compounds. The use of steroid, sodium cromoglycate and immunotherapy will be reviewed in this paper.
SUSTAINABILITY OF THE SOCIETY THROUGH GREEN HUMAN RESOURCES MANAGEMENT PRACTICES
Authors: DANLADI NSON YILKES 
Published: September 2023

Purpose This study attempts to evaluate and fill the knowledge gap by providing empirical evidence of the relationship between green HRM practices (Green recruitment and selection; green training and development; green performance management and appraisal; green pay and reward, and green involvement) and environmental performance based on the theory of Resources based view, Dynamic capabilities theory and Triple bottom line theory.
Design/methodology/approach A detailed review of empirical and conceptual articles related to the topic was the adopted methodology. An eclectic analysis and synthesis of the evidence guided the development and presentation of the framework as proposed.
Findings Empirical review of the related studies reveals that green HRM practices positively determine sustainability of the society through corporate organization adoption of environmental practices. Based on the theoretical foundation of the study, Green human resources management practices is proposed to have a direct link on sustainability of the society and an indirect link mediated by environmental practices. Controllable variables proposed include age, sex, size, level of education, work experience and feedback.
Research limitations/implications Green human resources management practices is conceived as an experienced construct conceptualized as the used of the basic well-known concepts of HRM, its policies, practices, systems, objectives, functions, processes, activities, and strategies in an environmentally friendly manner that is mutually beneficial to both the individual, the society, the natural environment, and the business organization.
Practical Implications The study provides a framework of green human resources management practices, sustainability of the society and adoption of environmental practices as mediating variable.
Originality/value The framework extends the ontological field of green human resources management practices (green recruitment and selection; training and development; performance management and appraisal; pay and reward, and involvement) which can be validated by empirical research.
Neighborhood selection using the analytical network process method for the capacitated vehicle routing problems
Authors: Takan Melis Alpaslan , Öztürk Zehra Kamışlı 
Published: September 2023

Highlights:

Analytical Network Process (ANP) is, for the first time, applied to select the best neighborhood structure of CVRP.
ANP considers tangible and intangible criteria and relationships between criteria.
Computational results indicate the importance of applying ANP.
ANP examines the behaviors of the test problems by considering different criteria.

Goal: This scientific research article focuses on developing a performance measurement framework for selecting the neighborhood structure of the capacitated vehicle routing problem using the ANP. The study aims to analyze the studied VRP as a multi criteria decision making process to determine the most efficient neighborhood structure.
Design / Methodology / Approach: The first step was using the different neighborhood operators of the vehicle routing problem which were 2-opt, swap, and insert to analyze the problem as a multi criteria decision making process to determine the most efficient neighborhood structure for the problem under study. Secondly, ANP model was developed for the regarding problem to compare these structures to find the best one for the problem.
Results: The results demonstrate that 2-opt is the best alternative for the studied CVRP. The studied approach can be used for any other type of the vehicle routing problems.
Limitation of the investigation: Thirty-three test problems were determined for three different neighborhood structures. All calculation results were given in detail for comparison on different test problems taken from the literature.
Practical implications: The significant contribution of this study is to help logistics companies select the most appropriate neighborhood structure to be used in solving the problem to get quality results in a very short time
Originality / Value: To the best of our knowledge, in the literature, there has not been any research comparing the effects of neighborhood structures on the vehicle routing problem by analyzing ANP methodology.
Holocaust Legacies and Oral History in the Classroom
Authors: Gibbs Chad S. A. 
Published: September 2023

Abstract
Survivor oral histories have helped determine research questions in Holocaust studies and propelled the field’s largest archival efforts. With those storytellers now passing at an ever-quickening pace, however, some oral historians are turning to descendants as the faces of memory. These researchers work with descendants to individualize the enormity of Holocaust history in classrooms and for wider audiences. Historians recognize that succeeding generations are not eyewitnesses to the Holocaust, though they can give voice to the lived legacies of genocide. I seek to bring these experiences into my teaching in a way that also produces indelible sources for future research. To this end, I recently began teaching a course called “Holocaust Legacies and Oral History.” Students in this class each conduct a recorded interview with a descendant of survivors. Students and professor work as a team to define the historical purposes of our interviews, draft questions, and prepare. This article the results of this class in terms of pedagogies, successes, areas for improvement, and connections created between classroom and community. The methods employed in this class are affordable and usable at virtually any interested institution.
Theoretical and experimental investigation of electricity generation through footstep tiles
Authors: Asif Muhammad , Iqbal Faisal , Esbhani Hamas , Ahmed Mirza Taha , Saqib Muhammad Uneeb 
Published: September 2023

Abstract
The current study aims to utilize population expansion by introducing a specially designed footsteps tiles mechanism capable of converting kinetic energy from footsteps into electricity. A rack and pinion mechanism was implemented due to its straightforward installation process and relatively high-power generation. However, addressing user comfort was crucial, as the mechanism caused significant deflections. As a result, a footstep tile mechanism was devised, manufactured, and thoroughly examined through both experimental and simulation methods. The CAD design of the mechanism was developed in SOLIDWORKS, dynamic models were created, and the system characteristics were analyzed using the simulation tool SIMULINK MATLAB®. Based on the optimal design obtained through dynamic simulations, the mechanism was fabricated, tested, and analyzed. The testing phase demonstrated an average of 9 V generated per footstep, yielding an estimated mechanical output power of 8.5 W per footstep, with a mechanical-to-electrical conversion efficiency of 15.6 %. The proposed setup presents a promising roadmap for large-scale electricity generation in densely populated areas such as institutes, hospitals, railway stations, and similar locations.
Examining the evacuation routes of the sister village program by using the ant colony optimization algorithm
Authors: Muhammad Aziz , Wu Taixia 
Published: September 2023

Abstract
Evacuation routes are necessary to guide people to avoid hazardous and dangerous zones and to prevent the loss of human lives, especially in the event of volcanic eruptions. This article attempts to examine the evacuation routes of the sister village program by using the ant colony optimization (ACO) algorithm. Model simulations and calculations of the ACO algorithm were done by aggregation of the five determined parameters including distance, speed, hurdle, density, and secure point. The validation of the model was carried out by the examination of the five most prone disaster villages located in Mount Merapi that are interconnected as sister villages in Sleman Regency, Yogyakarta Province, and Indonesia. This research is important to ensure that the sister village evacuation system is effective in reducing the impact of the risks posed by the eruption of Mount Merapi. Based on the results, sister village evacuation systems are proven to be the fastest and safest routes by the ACO examination
In vitro anti-cancer and antimicrobial effects of manganese oxide nanoparticles synthesized using the Glycyrrhiza uralensis leaf extract on breast cancer cell lines
Authors: Althobiti Maryam Musleh , Alzahrani Badr , Elderdery Abozer Y. , Alzerwi Nasser A. N. , Rayzah Musaed , Elkhalifa Ahmed M. E. , Idrees Bandar , Bakhsh Ebtisam , Alabdulsalam Abdulrahim A. , Mohamedain A. , Kumar Suresh S. , Mok Pooi Ling 
Published: September 2023

Abstract
In this study, we evaluated the antiproliferative and apoptotic properties of Pluronic-F127-containing manganese oxide nanoparticles (PF-127-coated Mn2O3 NPs) derived from the leaf extract of Glycyrrhiza uralensis (GU) on breast adenocarcinoma, MCF7, and MDA-MB-231 cell lines. The leaf extract of GU contains bioactive molecules that act as a reducing or capping agent to form Mn2O3 NPs. Various analytical techniques were used to characterize the physiochemical properties of PF-127-coated Mn2O3 NPs, including spectroscopy (ultralight-Vis, Fourier transform infrared, photoluminescence), electron microscopy (field emission scanning electron microscopy and transmission electron microscopy), X-ray diffraction (XRD), electron diffracted X-ray spectroscopy (EDAX), and dynamic light scattering. The average crystallite size of Mn2O3 NPs was estimated to be 80 nm, and the NPs had a cubic crystalline structure. PF127-encapsulated Mn2O3 NPs significantly reduce MDA-MB-231 and MCF-7 cell proliferation, while increasing endogenous ROS and lowering mitochondrial matrix protein levels. DAPI, EtBr/AO dual staining, and Annexin-V-FITC-based flow cytometry analysis revealed that PF127-coated Mn2O3 NP-treated breast cancer cells exhibit nuclear damage and apoptotic cell death, resulting in cell cycle arrest in the S phase. Furthermore, PF127-encapsulated Mn2O3 NPs show strong antimicrobial efficacy against various strains. As a result, we can conclude that PF127-coated Mn2O3 NPs may be effective as future anticancer agents and treatment options for breast cancer.
Preparation of Pd/Ce(F)-MCM-48 catalysts and their catalytic performance of n-heptane isomerization
Authors: Cui Yanhong , Suo Yanhua , Zhang Wei , Wang Yingjun , Nie Chunhong , Wang Yanhong 
Published: September 2023

Abstract
Ce and F were added to MCM-48 molecular sieve by hydrothermal synthesis, and Pd/Ce(F)-MCM-48 metal acid bifunctional catalysts were prepared by impregnation method. The physical and chemical properties of Ce(F)-MCM-48 and Pd/Ce(F)-MCM-48 were characterized by X-ray diffraction, scanning electron microscope, NH3 temperature programmed desorption instrument, Fourier infrared spectrometer, and X-ray photoelectronic spectrometer characterization methods. The results showed that when the molar ratio of the raw materials was n(Ce):n(TEOS) = 0.02 and n(NaF):n(TEOS) = 0.10, Ce(F)-MCM-48-0.10 molecular sieve had a high degree of order and large specific surface area and pore volume, the total acid content increased, and the acid strength also increased. And it had an acidic center and generated certain oxygen vacancies. The catalyst prepared after Pd impregnation had good dispersibility. 0.4% Pd/Ce(F)-MCM-48-0.10 catalyst still maintained the crystalline phase of MCM-48 molecular sieve. A micro-reaction device was used to examine the catalytic performance of n-heptane isomerization of Pd/Ce(F)-MCM-48-0.10 catalysts. When the hydrogen flow rate was 30 mL·min−1, reduction temperature was 300°C, reduction time was 4 h, weight hourly space velocity was 7.6 h−1, and reaction temperature was 280°C, 0.4% Pd/Ce(F)-MCM-48-0.10 catalyst was used in the heptane isomerization reaction, where the conversion of n-heptane was 67.3% and the selectivity of isoheptane was 96.5%.
Impact of magnetic spinel ferrite content on the structure, morphology, optical, and magneto-dielectric properties of BaTiO3 materials
Authors: Slimani Yassine , Meena Sher Singh , Shirsath Sagar E. , Hannachi Essia , Almessiere Munirah A. , Baykal Abdulhadi , Sivakumar Rengasamy , Batoo Khalid M. , Thakur Atul , Ercan Ismail , Özçelik Bekir 
Published: September 2023

Abstract
In this study, the influence of magnetic content of NiFe1.93Dy0.07O4 spinel ferrite on the structural, morphological, optical, and magneto-dielectric properties of BaTiO3 materials was investigated. NiFe1.93Dy0.07O4 magnetic nanoparticles and BaTiO3 dielectric materials were firstly synthesized using the hydrothermal method and sol–gel auto-combustion route, respectively. Then, different contents of the magnetic nanoparticles were added to BaTiO3 to form a series of BaTiO3/(NiFe1.93Dy0.07O4)
x
samples (abbreviated as BTO/(NDFO)
x
) with x = 0, 2, 5, 10, 20, and 100 %. The analysis of the structure via X-ray diffraction (XRD) technique revealed a transformation from a tetragonal structure for the pristine BTO sample to a cubic structure upon the inclusion of magnetic nanoparticles. The morphological observations and chemical composition analyses via scanning electron microscope (SEM) coupled with EDX system showed the successful formulation of biphasic products. The optical properties were investigated, and it was found that the inclusion of the magnetic phase diminishes the bandgap energy (E

g
) of final BTO/(NDFO)
x
samples. Furthermore, vibrating sample magnetometer (VSM) was used to investigate the magnetization properties. The values of saturation magnetization (M

S
) and remanent (M

r
) magnetization are rising with the increase of magnetic phase content. However, the coercivity (H

c
) does not show a regular variation with the increase of NDFO content. The dielectric properties were also investigated for different BaTiO3/(NiFe1.93Dy0.07O4)
x
samples. The obtained results showed that the real permittivity (ε′) and dielectric tangent loss (tan δ) increased with increasing temperature. Remarkably, the addition of magnetic content provokes a reduction in tan δ values compared to the pristine BTO sample. The lowest values of tan δ and highest frequency stability were noticed in the sample added with 10 % of magnetic phase. The impedance and modulus were also determined and discussed.