bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review on Vitamin D Deficiency
Authors: Shukla Priya , Kumari Mamta , Pandey Mayankesh 
Published: April 2023

Vitamin D is a fat-soluble vitamin that plays an important role in bone metabolism and seems to have some anti-inflammatory and immune-modulating properties. In addition, recent epidemiologic studies have observed relationships between low vitamin D levels and multiple disease states. Low vitamin D levels are associated with increased overall and cardiovascular mortality, cancer incidence and mortality, and autoimmune diseases such as multiple sclerosis. Although it is well known that the combination of vitamin D and calcium is necessary to maintain bone density as people age, vitamin D may also be an independent risk factor for falls among the elderly.
Vitamin D had been linked to skeletal disease including calcium, phosphorus, and bone metabolism, osteoporosis, fractures, muscle strength, and falls. In the 2000s, growing scientific attention turned to non-skeletal chronic diseases as vitamin D deficiency was linked to cancer, cardiovascular diseases, metabolic disorders, infectious diseases, and autoimmune diseases, as well as mortality.
Outcome of Knee Reconstruction using Saphenous Artery-Based Fasciocutaneous Flap: A retrospective study
Authors: Abd-Elghany Salah Mohammed , Moawad Mahmoud Mohammed , Abdelhameed Hifny  
Published: April 2023

Background and Aim: The soft tissue defects around the knee are common and represents a challenge for surgeons due to its complexity and desired outcome. Many reconstructive treatment options are available and flaps are recommended. The current study aimed to evaluate the outcome of using saphenous artery (SA)-based flaps for the management of soft tissue defects around the knee.
Methodology: Files of 34 patients treated by SA-based flaps were reviewed for outcome and complications. Collected data included patient demographics, etiology, size, site and side of the defect and outcome (flap survival and complications) at the end of the 6th postoperative month.
Results: There were 26 males and 8 females. Their age ranged from 18 to 45 years; the mean age was 33.18±6.58 years. The commonest etiology was posttraumatic (64.7%) then post-burn contracture (20.6%). The majority of defects were on the right side (82.4%). The maximum length of the defect ranged between 14 and 20 cm (mean ± SD were 16.56±1.62) while the maximum width ranged between 6 and 10 cm (mean ±SD were 8.59±1.05). The flap survival rate was 97.1%. The overall complications rate was 14.7%, distal flap necrosis reported for 5.9%, wound dehiscence for 2.9% and seroma for 5.9%. All treated conservatively, except that of distal flap necrosis which need reintervention.
Conclusion: The saphenous artery-based fasciocutaneous flap is an effective, feasible and safe option for the management of soft tissue defects around the knee.
Musculoskeletal pain: pharmacological treatment
Authors: Guerrasio Stefano 
Published: April 2023

Abstract
Pain has the aim of identifying a harmful stimulus and avoiding tissue damage. Acute pain has recent onset and limited duration, while chronic pain is caused by continuous tissue damage or alteration in the pathways of transmission. Musculoskeletal pain is defined as acute and/or chronic pain affecting bones, muscles, ligaments, tendons and nerves. Medical literature about clinical aspects of pain, with particular focus on musculoskeletal pain, was reviewed and combined with expert opinion of the authors. The simultaneous use of drugs with different mechanisms of action (multimodal approach) allows a more effective analgesia with better tolerability. Paracetamol is a known molecule with analgesic and antipyretic activity, better tolerated than NSAIDs. Codeine is a natural opioid that inhibits transmission at the level of the spinal synapse and enhances the action of inhibitory descending pathways. The two drugs have a similar half-life, and the same time of onset and duration of analgesic activity. Many randomized studies have shown that this combination is more effective and better tolerated than NSAIDs and the combination of paracetamol/tramadol in different types of pain, i.e. postoperative, musculoskeletal, dental, headache, osteoarthritis, polytrauma. The Italian Intersociety group recommends the use of paracetamol and the combination paracetamol/codeine 500/30 mg, repeatable every 6 hours, for the management of moderate pain in the emergency setting.
Due to its safety and tolerability, paracetamol alone or in combination with codeine remains a first-choice treatment of mild-moderate pain, and its lack of cardiovascular and gastric toxicity represents a valid alternative to NSAIDs.
The investigation of a unbalanced barrel pitching system’s characteristics degradation and compensation under gradual erosion behavior
Authors: CHU Yuanbo , XIA Yunxia 
Published: April 2023

The unbalanced barrel pitching system is a typical electro-hydraulic coupling servo control system, the performance of which determines the response speed and hit probability of vehicle mounted weapon equipment. However, in the actual service process, its core component, the high precision jet pipe servo valve, will produce the gradual erosion of the pilot stage’s receivers and the power stage’s throttling edges, which will induce the performance degradation of the unbalanced barrel pitching system, and finally greatly reduce the performance of barrel weapons. Therefore, a pressure and position double loop state space model of unbalanced barrel pitching system including the core parameters of performance degradation is established. The erosion behavior mechanism model of jet pipe servo valve is constructed, and the performance degradation characteristics of the unbalanced barrel pitching control system under the condition of erosion are further analyzed. Finally, aiming at the double loop structure of internal pressure loop and external position loop, the RBF Network Adaptive Robust Sliding Mode-Proportional Integral Derivative two-stage controller of barrel system is designed, based on which the experimental platform of unbalanced barrel pitching control is built. The experimental results are in good agreement with the theoretical results, so the proposed control method can effectively suppress the degradation of internal structural parameters induced by erosion, that is, it can better compensate the performance degradation of barrel pitching system induced by gradual erosion behavior.
Celebrity appearance-shaming: Innocent bashing forms or reconfirming gender norms? A study into the explanations of adolescents’ celebrity appearance-shaming intentions
Authors: Ouvrein Gaëlle 
Published: April 2023

Celebrities regularly become victims of online body- and slut-shaming. This study refers to these practices as appearance-shaming and investigates potential explanations for adolescents’ intentions to participate in this behavior by means of an extended version of the theory of planned behavior (TPB). Apart from the three paths of attitudes toward the practice, subjective norms about the practice, and perceived behavioral control to participate in it, we added sexism as a potential variable to explain celebrity appearance-shaming. Through this addition, we were better able to capture the role of cultural background variables, something that was not included in the traditional elements of the TPB but appeared to be important for explaining normative behaviors. Based on a survey study of 248 adolescents (N = 248), we concluded that the TPB is a good theoretical framework for explaining intentions toward celebrity appearance-shaming. More specifically, having more accepting attitudes toward celebrity bashing, more supportive descriptive norms about celebrity bashing, and higher perceived behavioral control were associated with higher intentions. Moreover, sexism had a strong positive relationship with the intention to celebrity appearance-shaming. Participating in celebrity appearance-shaming might, in that way, be an indicator of strong traditional sexist beliefs and might contribute to keeping them alive among adolescents.
What is the post-game depression? A narrative inquiry
Authors: Klimczyk Piotr 
Published: April 2023

Despite the fact that video games and gaming are one of the main focuses of scholars in the field of cyberpsychology, there are a lot of phenomena that hardly get any scientific cover. One of them is post-game depression, a term coined in the gamers community to express a specific state that some of them experience after playing certain video games. However, as to the authors’ knowledge, there has been no research focusing on understanding that state. Based on the findings of narrative psychology, a narrative inquiry approach was chosen for the presented qualitative, exploratory study. Using guidelines from the interpretative phenomenological analysis, the final sample of 35 given narratives of players were analysed, of which 22 described post-game depression and 13 of narrators described reasons why they did not experience it. After comparing the results between the two groups, the general conclusion is that post-game depression is a state of media anhedonia and reminiscing about the game that gave a visceral, insightful, thought-provoking and emotionally driven experience where players had parasocial relationships with in-game characters and/or their avatars/protagonists. Possible buffer factors can be personal growth from the experience and a fulfilling ending for the player. It is important to further understand what other factors, for example, personal traits of the players and specific game mechanics, contribute to that state since it can be a possible cause of serious psychological distress on the one hand, on the other a possible phase of being personally enriched by the experience of playing certain video games.
10+1 principios para el espacio público de la era post-coronavirus: a través de un proyecto: La Campa de La Teixonera
Authors: Zaldivar Javier 
Published: April 2023

El urbanismo moderno surgió como consecuencia de la crisis sanitaria y
habitacional originada por la Revolución Industrial, y ante la necesidad de
resolver las condiciones de vida de una población hacinada en barrios insalubres
de ciudades a las que habían emigrado en busca de una vida mejor.
170 años después, otra crisis sanitaria (una pandemia provocada por el COVID-
19) nos hace reflexionar sobre la forma urbana actual, y en especial sobre
el espacio público de nuestras ciudades: calles y plazas, jardines y parques,
paseos fluviales y frentes marítimos. Somos más conscientes de sus aciertos,
pero sobre todo nos hemos dado cuenta de sus defectos.
Este artículo presenta una reflexión sobre las características que debe incluir
un proyecto de espacio público, a partir de mi experiencia profesional, docente
e investigadora. 10+1 principios condensados en el último proyecto
diseñado y ejecutado en el despacho: La Campa de La Teixonera. Sirva esta
reflexión en pleno confinamiento como aportación personal al intercambio
de conocimientos que ya se ha iniciado sobre el futuro del espacio público de
la era post-coronavirus.
Modern urbanism was born as a consequence of the serious health crisis caused by the Industrial Revolution. All those people who migrated to the cities seeking a better life had to live in unhealthy neighborhoods. 170 years later, another health crisis (a pandemic caused by COVID-19) makes us reflect on the urban current situation, especially on the public space of our cities: streets and squares, gardens and parks, river walks and seafronts. We really appreciate its successes, but above all we have become aware of its errors. This article presents a reflection on the characteristics that a public space project should include, based on my professional, teaching and research experience. 10+1 principles condensed in the last project designed and executed by my firm: La Campa de La Teixonera. I hope this lockdown reflection will serve as a personal contribution to the exchange of knowledge that has already begun around the future of public space in the new post-coronavirus era.
L’Eix Besòs: una mirada desde las soluciones basadas en la naturaleza
Authors: Ramírez Agudelo Nancy Andrea , Porcar Anento Roger , Villares Junyent Míriam , Roca Bosch Elisabet 
Published: April 2023

La complejidad de los desafíos sociales promueve enfoques con múltiples beneficios, como las soluciones basadas en la naturaleza (SBN). Las SBN integran aspectos ambientales, sociales y económicos a través de su enfoque exhaustivo, lo cual dificulta su operativización. Las SBN promueven una relación más dinámica de la ciudad con la naturaleza, que hace del verde urbano un área de innovación, implicando un mayor esfuerzo en la gestión urbana. Este artículo expone el caso de L’Eix Besòs en el Área Metropolitana de Barcelona desde la mirada de las SBN, analizando la transformación del Parque Fluvial del Besòs cómo una respuesta basada en aspectos medioambientales, sociales y de gestión urbanística. En las últimas décadas la transformación de L’Eix Besòs a través del frente de agua, la recreación, el pasear y la contemplación han facilitado que este paisaje de polígonos urbano y peri-urbano se convierta en un ejemplo de renaturalización. Actualmente, el encuentro del Río Besòs con el frente litoral Mediterráneo, es un paisaje en transformación que evidencia los desafíos de la metrópoli contemporánea, donde el enfoque exhaustivo de las SBN podría ser una ventaja para una transición urbana sostenible, a partir de un dialogo transdisciplinar, soportado en unas capacidades (sociales y técnicas) construidas.
The complexity of societal challenges promotes multi-benefit approaches such as nature-based solutions (NBS). NBS integrate environmental, social and economic aspects through their exhaustive approach, which makes their operationalization difficult. NBS promote a more dynamic relationship between the city and nature, which makes urban green an area of innovation, implying a greater effort in urban management. This article presents the case of l’Eix Besòs in the Barcelona Metropolitan Area from the NBS perspective, analyzing the Besòs River Park intervention as a response based on environmental, social and urban management aspects. In recent decades, the l’Eix Besòs transformation through the waterfront, recreation, walking and contemplation have made this landscape of urban and peri-urban polygons an example of re-naturalization. Currently, the meeting of the Besòs River with the Mediterranean coastline is a landscape in transformation that shows the challenges of the contemporary metropolis, where the NBS exhaustive approach could be an advantage for a sustainable urban transition, based on a transdisciplinary dialogue, supported by built capacities (social and technical).
El tejido residencial en la transformación urbana de ciudades intermedias de la región metropolitana de Barcelona (1980-2020)
Authors: Fortuny Vila Joan Antoni , Peremiquel Lluch Francisco 
Published: April 2023

El estudio de los tejidos residenciales en la transformación de la segunda corona
metropolitana entre el 1980 y 2020, pretende mostrar su incidencia en
transformación del territorio y señalar algunos retos futuros de las ciudades
intermedias.
En los últimos 40 años los fragmentos residenciales, junto a la construcción
de infraestructuras viarias y el desarrollo las áreas de actividad económica,
han sido determinantes para su transformación. Los nuevos tejidos complementan
y renuevan la ciudad con viviendas, equipamientos, espacios libres
y reconfiguran la lógica interna a través de las avenidas, rondas y variantes.
Apoyados en el tejido existente, transforman la ciudad produciendo el cambio
de escala y redefiniendo los límites. Proyectos de escala intermedia, los
fragmentos residenciales, que se integra en la ciudad y construye un entorno
mejorado.
Como resultado, han renovado la ciudad modificando la estructura general
con la incorporación de tramas y tejidos nuevos, modificando las relaciones
entre las partes y con ello, cambiando la imagen de la ciudad. Los nuevos
estándares aplicados han permitido desarrollar una ciudad más pública y
abierta, con más espacios públicos, dotaciones y mayor calidad urbana para
sus habitantes.
The study of the residential fabrics in the transformation of the second metropolitan crown between 1980 and 2020, aims to show its incidence in the transformation of the territory and point out some future challenges for intermediate cities. In the last 40 years, the residential fragments, together with the construction of road infrastructures and the development of areas of economic activity, have been decisive for its transformation. The new fabrics complement and renew the city with houses, facilities, free spaces and reconfigure the internal logic through avenues, roundabouts and variants. Supported by the existing fabric, they transform the city, producing a change of scale and redefining the limits. Intermediate-scale projects, residential fragments, which are integrated into the city and build an improved environment. As a result, they have renovated the city by modifying the general structure with the incorporation of new frames and fabrics, modifying the relationships between the parts and with it, changing the image of the city. The new standards applied have made it possible to develop a more public and open city, with more public spaces, facilities and greater urban quality for its inhabitants.
TRPS1 and GATA3 Expression in Invasive Breast Carcinoma With Apocrine Differentiation
Authors: Wang Jing , Peng Yan , Sun Hongxia , Aung Phyu P. , Resetkova Erika , Yam Clinton , Sahin Aysegul A. , Huo Lei , Ding Qingqing 
Published: April 2023

Context.—
The recently identified immunohistochemical marker TRPS1 is highly sensitive and specific for invasive breast carcinoma, especially triple-negative breast carcinoma. However, TRPS1 expression in special morphologic subtypes of breast cancer is unclear.

Objective.—
To investigate the expression of TRPS1 in invasive breast cancer with apocrine differentiation, in comparison to the expression of GATA3.

Design.—
A total of 52 invasive breast carcinomas with apocrine differentiation, comprising 41 triple-negative breast carcinomas and 11 estrogen receptor (ER) and progesterone receptor (PR)–negative, human epidermal growth factor receptor 2 (HER2)–positive cases, along with 11 triple-negative breast carcinomas without apocrine differentiation, were evaluated for TRPS1 and GATA3 expression by immunohistochemistry. All tumors were diffusely positive (&gt;90%) for androgen receptor (AR).

Results.—
Triple-negative breast carcinoma with apocrine differentiation had positive TRPS1 expression in 12% of cases (5 of 41), whereas GATA3 was positive in all cases. Similarly, HER2+/ER− invasive breast carcinoma with apocrine differentiation showed positive TRPS1 in 18% of cases (2 of 11), whereas GATA3 was positive in all cases. In contrast, triple-negative breast carcinoma with strong AR expression but without apocrine differentiation showed both TRPS1 and GATA3 expression in 100% (11 of 11) of cases.

Conclusions.—
Most ER−/PR−/AR+ invasive breast carcinomas with apocrine differentiation are TRPS1 negative and GATA3 positive, regardless of HER2 status. Therefore, TRPS1 negativity does not exclude breast origin in tumors with apocrine differentiation. A panel of TRPS1 and GATA3 immunostains can be helpful when the tissue origin of such tumors is clinically relevant.
The Application and Pitfalls of Immunohistochemical Markers in Challenging Diagnosis of Genitourinary Pathology
Authors: Li Jianhong , Wilkerson Myra L. , Deng Fang-Ming , Liu Haiyan 
Published: April 2023

Context.—
The morphologic features of different entities in genitourinary pathology overlap, presenting a diagnostic challenge, especially when diagnostic materials are limited. Immunohistochemical markers are valuable when morphologic features alone are insufficient for definitive diagnosis. The World Health Organization classification of urinary and male genital tumors has been updated for 2022. An updated review of immunohistochemical markers for newly classified genitourinary neoplasms and their differential diagnosis is needed.

Objective.—
To review immunohistochemical markers used in the diagnosis of genitourinary lesions in the kidney, bladder, prostate, and testis. We particularly emphasized difficult differential diagnosis and pitfalls in immunohistochemistry application and interpretation. New markers and new entities in the 2022 World Health Organization classifications of genitourinary tumors are reviewed. Recommended staining panels for commonly encountered difficult differential diagnoses and potential pitfalls are discussed.

Data Sources.—
Review of current literature and our own experience.

Conclusions.—
Immunohistochemistry is a valuable tool in the diagnosis of problematic lesions of the genitourinary tract. However, the immunostains must be carefully interpreted in the context of morphologic findings with a thorough knowledge of pitfalls and limitations.
การพัฒนารูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น
Authors:   , ถาวรรัตนวณิช สมาน 
Published: April 2023

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1) เพื่อพัฒนารูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น 2) เพื่อศึกษาผลการใช้รูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น กลุ่มตัวอย่างคือนักเรียนชั้นมัธยมศึกษาตอนต้นที่ทำโครงงานนวัตกรรม เครื่องมือที่ใช้ในการวิจัย ได้แก่ 1) แบบประเมินรูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น 2) แบบสำรวจตนเองเกี่ยวกับคุณลักษณะเชิงสร้างสรรค์ 3) แบบรายงานตนเองเกี่ยวกับแรงจูงใจในการทำงาน (ขั้นระบุงาน) 4) แบบรายงานตนเองเกี่ยวกับแรงจูงใจในการทำงาน (ขั้นการสร้างการตอบสนอง) 5) แบบรายงานตนเองเกี่ยวกับทักษะที่สอดคล้องกับความคิดสร้างสรรค์ 6) แบบประเมินทักษะที่สอดคล้องกับคณิตศาสตร์ วิทยาศาสตร์ กระบวนการทางวิศวกรรมและเทคโนโลยีด้วยเกณฑ์การให้คะแนน 7) แบบประเมินผลงานเชิงสร้างสรรค์ ผลการวิจัยพบว่า 1. รูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น ประกอบด้วยการประเมิน 3 ด้าน ได้แก่ 1) ด้านคุณลักษณะบุคคล เป็นการประเมินคุณลักษณะเชิงสร้างสรรค์ที่เป็นภูมิหลังของนักเรียน 2) ด้านกระบวนการ ซึ่งเป็นการประเมินความก้าวหน้า โดยประเมินแรงจูงใจในการทำงาน ทักษะที่สอดคล้องกับความคิดสร้างสรรค์ และทักษะที่สอดคล้องกับคณิตศาสตร์ วิทยาศาสตร์ กระบวนการทางวิศวกรรมและเทคโนโลยี 3) ด้านผลงานซึ่งเป็นการประเมินรวบยอดเป็นการประเมินความคิดสร้างสรรค์ผ่านชิ้นงานนวัตกรรม รูปแบบได้รับการประเมินจากผู้เชี่ยวชาญว่า มีความเหมาะสมระดับมาก (Mean = 4.48, S.D. = 0.05) และมีความเป็นไปได้ระดับมาก (Mean = 4.39, S.D. = 0.08) 2. ผลการทดลองใช้รูปแบบการประเมินความคิดสร้างสรรค์ผ่านการทำโครงงานนวัตกรรมของนักเรียนชั้นมัธยมศึกษาตอนต้น พบว่า บริบทของโครงงานที่ใช้กรอบเนื้อหาหลักสูตรกำหนดหัวข้อ คะแนนที่ได้จากการประมินชิ้นงานของกลุ่มทดลอง (M = 3.32, SD = .13) สูงกว่ากลุ่มควบคุม (M = 3.18, SD = .18) อย่างมีนัยสำคัญทางสถิติที่ระดับ .05 สำหรับบริบทของโครงงานเพื่อแก้ปัญหาชีวิตประจำวัน คะแนนที่ได้จากการประเมินชิ้นงานของกลุ่มทดลอง (Mean = 3.31, S.D. = 0.17) และกลุ่มควบคุม (Mean = 2.95, S.D. = 0.30) ไม่แตกต่างกัน เมื่อพิจารณามิติการประเมินย่อยพบว่า กลุ่มทดลอง (Mean = 3.25, S.D. = 0.23) มีคะแนนมิติการคิดริเริ่มสูงกว่า กลุ่มควบคุม (Mean = 2.79, S.D. = 0.20) อย่างมีนัยสำคัญที่ระดับ .05 นอกจากนี้ยังพบว่า นักเรียนได้รับข้อมูลที่เป็นประโยชน์จากการประเมินตนเองเกี่ยวกับทักษะที่สอดคล้องกับความคิดสร้างสรรค์ไปปรับปรุงตนเองได้ รวมทั้งครูได้ข้อมูลจากการประเมินด้านกระบวนการไปใช้ในการให้ข้อมูลย้อนกลับแก่นักเรียน