bluuebunny/crossref_metadata_2025_split huggingface dataset:
A three-dimensional stochastic structure model derived from high-resolution isolated equatorial plasma bubble simulations
Authors: Rino Charles , Yokoyama Tatsuhiro , Carrano Charles 
Published: April 2023

AbstractIonospheric structure is characterized by the space–time variation of electron density. However, our understanding of the physical processes that initiate and sustain intermediate-scale structure development does not relate directly to statistical measures that characterize the structure. Consequently, high-resolution physics-based equatorial plasma bubble simulations are essential for identifying systematic relations between statistical structure measures and the underlying physics that initiates and sustains the structure evolution. An earlier paper summarized the analysis of simulated equatorial plasma bubble (EPB) structure initiated with a quasi-periodic bottom-side perturbation that generated five plasma bubbles. The results are representative of real environments. However, the association of the structure development with individual EPBs was difficult to ascertain. This paper summarizes the analysis of new results from single isolated EPB realizations with varying parameters that affect the structure development. The evolution of the single isolated EPB realizations reveal what we have identified as a canonical structure evolution pattern manifest in the space–time development of four quantitative spectral parameters. The onset of structure occurs when the plasma bubble penetrates the F-region peak. The parameter evolution from the initiation point have a fish-like appearance. The three-dimensional structure model can be used to interpret in situ and remote diagnostic measurements as well as predicting the deleterious effects of propagation disturbances on satellite communication, navigation, and surveillance systems.
Graphical Abstract
Patient-centric soulbound NFT framework for electronic health record (EHR)
Authors: Tanwar Namrta , Thakur Jawahar 
Published: April 2023

AbstractInterest in leveraging blockchain technology to boost healthcare and e-health solutions has lately increased. Blockchain has proven to have enormous promise in a range of e-health industries because of its decentralized and reliable nature, including the secure exchange of electronic health records (EHRs) and database access management among numerous medical entities. A unique paradigm known as the “patient-centric approach” places the patient at the center of the healthcare system and gives them complete control over who has access to and can share their personal health information. Strong confidentiality and safety requirements are necessary for health information. Additionally, other concerns must be resolved, such as secrecy, interoperability, scalability, cost-effectiveness, and timeliness. This paper offers a patient-centric privacy-preserving framework for an efficient and safe medical record to address these problems. Based on three parameters transaction cost, execution time, and gas cost. Three blockchain platforms are compared by using the smart contract to find out the suitable platform for the implementation of this framework. Blockchain platforms served as a benchmark for the performance assessment of a designed framework. Although blockchain will not fix every issue in healthcare organizations, it will undoubtedly assist in dramatically reducing some of the most critical ones.
Risk Factors of Hyperglycemia After Treatment With the AKT Inhibitor Ipatasertib in the Prostate Cancer Setting: A Machine Learning–Based Investigation
Authors: Harun Rashed , Sane Rucha , Yoshida Kenta , Sutaria Dhruvitkumar S. , Jin Jin Y. , Lu James 
Published: April 2023

PURPOSE Hyperglycemia is a major adverse event of phosphatidylinositol 3-kinase/AKT inhibitor class of cancer therapeutics. Machine learning (ML) methodologies can identify and highlight how explanatory variables affect hyperglycemia risk. METHODS Using data from clinical trials of the AKT inhibitor ipatasertib (IPAT) in the metastatic castrate-resistant prostate cancer setting, we trained an XGBoost ML model to predict the incidence of grade ≥2 hyperglycemia (HGLY ≥ 2). Of the 1,364 patients included in our analysis, 19.4% (n = 265) of patients had HGLY ≥2 events with a median time of first onset of 28 days (range, 0-753 days), and 30.0% (n = 221) of patients on an IPAT regimen had at least one HGLY ≥2 event compared with 7.0% (n = 44) of patients on placebo. RESULTS An 11-variable XGBoost model predicted HGLY ≥2 events well with an AUROC of 0.83 ± 0.02 (mean ± standard deviation). Using SHapley Additive exPlanations analysis, we found IPAT exposure and baseline HbA1c levels to be the strongest predictors of HGLY ≥2, with additional predictivity of baseline measurements of fasting glucose, magnesium, and high-density lipoproteins. CONCLUSION The findings support using patients' prediabetic status as a key factor for hyperglycemia monitoring and/or trial exclusion criteria. Additionally, the model and relationships between explanatory variables and HGLY ≥2 described herein can help identify patients at high risk for hyperglycemia and develop rational risk mitigation strategies.
Considering Epidemiology’s Need for Literary History
Authors: Bezio Kelly L. 
Published: April 2023

Abstract
This essay explores the potential for literary history to be useful as a part of epidemiological sleuthing. It considers how an imperative to employ social determinants of health frameworks incites movement away from epidemiological plots, particularly the forward trajectory of the outbreak narrative and its privileging of containment as the solution to emerging infections. Instead, opportunities arise to explore how data about the history of present-day structural inequities offer better ways to combat the deleterious effects of outbreaks. Through an analysis of Harriet Wilson’s novel Our Nig, this essay lays out provisional ways in which literary history and those with expertise in it may prove an untapped resource for increasing our knowledge of how to prevent disproportionate risk of disease, debility, and death for people of color.
Knowledge about ultraviolet radiation (UVR) and attitudes and behaviour regarding gel manicure according to the age of women
Authors: Malinowska-Borowska Jolanta , Buczkowska Marta 
Published: April 2023

Introduction and purpose. Nowadays, artificial gel nails, which require Ultraviolet Radiation (UVR) for polymerization, steadily gain popularity. Gel manicure dried with UV lamps has become a regular part of many women's beauty routines. However, its safety remains controversial. The aim of the study was to assess the women’s knowledge of UVR and their attitudes towards UV nail exposure and its impact on human health.
Material and methods. The study was carried out from January to March 2020 with the use of PAPI and CAWI method. The study population consisted of 188 women living in the Silesian Voivodeship in Poland. The mean age was 31.7 ±12.4. The majority of women were familiar with UV nail polish drying devices (74%). Most of the respondents were regularly using UV lamps (51.1%).
Results. 62% of women aged 18-25 regularly got UV manicure, whereas only 29% of women older than 40 years (p<0.001). Most of the respondents got UV manicure at beauty salon. However, 37% of women got it also at home. Self-manicure was mostly popular among women at age 18-25 (p<0.001). Only 18.7% put sunscreen on hands and 10.8 % wore fingerless gloves. Simultaneous antibiotic therapy or artificial sunbathing was not a contraindication for 15% and 8% of women, respectively. The knowledge of respondents about UV radiation was poor. The rate of correct responses was 54.7%.
Conclusions. While existing research suggests a low risk of carcinogenesis resulting from UV nail lamp use, ways to minimize any risk should be kept in mind. Dermatologists should educate patients, especially those with photosensitivity disorders, tanning bed history or with family history of skin cancer and raise their awareness about the potential health risk of UV manicure. Photoprotection and fingerless gloves should be accessible in beauty salons and recommended to use during UV manicure. Safety regulations concerning UV lamps are needed because they are very often self-operated by many women at home.
Improving Mathematical Exposition of an Industrial-Scale Linear Program
Authors: Greivel Gus , Newman Alexandra , Brown Maxwell , Eurek Kelly 
Published: April 2023

Industrial-scale models require considerable setup time; hence, once built, they are used in myriad ways to consider closely related cases. In practice, the code for these models frequently evolves without appropriate notational choices, largely as a result of the lengthy development time of, and the number of individuals contributing to, their formulation. This leads to inefficiencies and obfuscates model structures that might be leveraged to expedite solutions. In this paper, we advocate for an emerging literature on model formulation “best practices” and present the reformulation of a widely used industrial-scale linear program. The efficient mathematical expression of this linear program, used to plan capacity expansion in the energy sector, allows for greater transparency of model structures and enhanced ability to identify computational performance improvements, as well as a lucid interpretation of its solutions. This type of formulation is employed in several mathematical programming courses at our university as an example of the advantages of best practices; the model more broadly is used widely to inform policy in the U.S. energy sector. Funding: This work was supported by the National Renewable Energy Laboratory (Laboratory Directed Research and Development program).
Sharing Sequentially Triggered Losses: Automated Conflict Resolution Through Smart Contracts
Authors: Gudmundsson Jens , Hougaard Jens Leth , Ko Chiu Yu 
Published: April 2023

When actions by one agent force another to deviate from their agreements with a third, “victim” turns into “injurer” in the chain’s subsequent steps. Should the chain’s initiator be responsible only for the direct harm they cause or also bear some of the indirect losses they trigger? Through an axiomatic approach, we characterize the class of fixed-fraction rules, which strike a balance between incentives for accident prevention on the one hand and fairness in terms of how liabilities are assigned on the other. Their simple design make the rules ideal for practical implementation through smart contracts, enabling automated conflict resolution. This paper was accepted by Manel Baucells, behavioral economics and decision analysis. Funding: J. Gudmundsson and J. L. Hougaard gratefully acknowledge financial support from the Carlsberg Foundation [Grant CF18-1112].
Short Communication: Differences in phytochemical compounds and antioxidant activity of Portulaca oleracea and Portulaca grandiflora
Authors: AISYAH SYARIFAH IIS , OKTAVIA ALDILA WIDYA PUTRI , AYUNINGTYAS AULIA ARDHIAN , PUTRA RAIHAN PERMANA , PRASSISKA SELNIS , JAMILAH SITI , NURCHOLIS WARAS 
Published: April 2023

Abstract. Aisyah SI, Oktavia AWP, Ayuningtyas AA, Putra RP, Prassiska S, Jamilah S, Nurcholis W. 2023. Short Communication: Differences in phytochemical compounds and antioxidant activity of Portulaca oleracea and Portulaca grandiflora. Biodiversitas 24: 1385-1390. Portulaca oleracea and Portulaca grandiflora are medicinal ornamental plants used in traditional and modern medicine. Therefore, this study aimed to analyze the phytochemical compounds and antioxidant activity in two purslane plants, P. oleracea,and P. grandiflora. The purslane ethanol extract was obtained by sonication and maceration methods. The phytochemical screening included the examination of secondary plant metabolites, while antioxidant activity was analyzed using the 2,2-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and cupric ion reducing antioxidant capacity (CUPRAC) methods. The results showed that both extract samples contain alkaloids, phenol hydroquinones, flavonoids, saponins, tannins, triterpenoids, and steroids. The highest ABTS antioxidant activity was found in P. grandiflora extract at 26.93 µmol TE/g FW compared to P. oleracea extract at 15.98 µmol TE/g FW. The highest CUPRAC antioxidant activity was found in the P. oleracea extract at 33.22 µmol TE/g FW, while in the P. grandiflora extract, it was 18.55 µmol TE/g FW. Based on the results, it was concluded that the chemical complexity of various purslane plants causes differences in the antioxidant capacity.
Evolutionary tracks of chromosomal diversification in Trichopsis (Anabantiformes, Osphronemidae) fishes: New insights from a molecular cytogenetic perspective
Authors: MINGKWAN BOONYADA , SASSI FRANCISCO DE MENEZES CAVALCANTE , MUANGLENM NAWARAT , PINMONGKHONKUL SITTHISAK , PINTHONG KRIT , TONGNUNUI SAMPAN , YEESIN PUN , TANOMTONG ALONGKLOD , LIEHR THOMAS , CIOFFI MARCELO DE BELLO , SUPIWONG WEERAYUTH 
Published: April 2023

Abstract. Mingkwan B, Sassi FDMC, Muanglenm N, Pinmongkhonkul S, Pinthong K, Tongnunui S, Yeesin P, Tanomtong A, Liehr T, Cioffi MDB, Supiwong W. 2023. Evolutionary tracks of chromosomal diversification in Trichopsis (Anabantiformes, Osphronemidae) fishes: New insights from a molecular cytogenetic perspective. Biodiversitas 24: 1551-1559. This study investigated the chromosomes of three Trichopsisspecies (namely Trichopsis pumila, Trichopsis vittata, and Trichopsis schalleri) using conventional (Giemsa stain, Ag-NOR) and molecularcytogenetic techniques. Fluorescence in situ hybridization (FISH) with repetitive DNAs, including 5S and 18S rDNAs, and microsatellites as probes were also performed. Our results indicated a conserved diploid number of 46 (2n) for all analyzed species of both sexes, although varying in their karyotype structure. Furthermore, T. schalleri and T. vittata karyotypes were presented with only acrocentric chromosomes (46a), while T. pumila had a submetacentric pair in addition to acrocentric ones (2sm+44a). Positive Ag-NOR sites were differentially found in each species adjacent to the acrocentric chromosome's centromeric and/or interstitial sub-centromeric regions. Both 5S and 18S rDNAs vary between the analyzed species, but all were localized in multiple sites. However, the distribution pattern of microsatellites differed in each species, mostly scattering at peri-centromeric and telomeric regions. These findings show that Trichopsis species, while having a conserved diploid number, differ significantly in the distribution of repetitive sequences in their karyotypes, particularly for rDNAs. These species-specific patterns can be useful for characterizing and identifying further different species and examining the evolutionary mechanisms that drove the evolution of these fishes' karyotypes.
Time to diabetic neuropathy and its predictors among adult type 2 diabetes mellitus patients in Amhara regional state Comprehensive Specialized Hospitals, Northwest Ethiopia, 2022: A retrospective follow up study
Authors: Tantigegn Sharie , Ewunetie Atsede Alle , Agazhe Moges , Aschale Abiot , Gebrie Muluye , Diress Gedefaw , Alamneh Bekalu Endalew 
Published: April 2023

BackgroundDiabetic neuropathy is the primary cause of foot ulcers and amputations in both industrialized and poor countries. In spite of this, most epidemiological research on diabetic neuropathy in Ethiopia have only made an effort to estimate prevalence, and the information underlying the condition’s beginning is not well-established. Therefore, determining the time to diabetic neuropathy and its variables among adult patients with type 2 diabetes mellitus at the Compressive Specialized Hospitals of the Amhara region was the aim of this study.MethodsAn institutional-based retrospective follow-up study was undertaken among 669 newly recruited adult patients with type 2 diabetes mellitus who were diagnosed between the first of March 2007 and the last day of February 2012. Patients with diabetic neuropathy at the time of the diagnosis for type 2 diabetes mellitus (T2DM), patients without a medical chart, patients with an unknown date of DM diagnosis, and patients with an unknown date of diabetic neuropathy diagnosis were excluded from the study. All newly diagnosed type 2 diabetes mellitus (T2DM) patients aged 18 years and older who were enrolled from 1st March 2007 to 28th February 2012 in selected hospitals were included in this study. Cox proportional hazard model was fitted to determine predictors of time to diabetic neuropathy, and the Kaplan Meier survival curve was used to assess the cumulative survival time. Variables with a p-value < 0.05 were considered to be statistically significance at 95% confidence interval.ResultsThe restricted mean survival time of this study was 179.45 (95% CI: 173.77–185.14) months. The overall incidence rate of diabetic neuropathy was 2.14 cases per 100 persons-years. Being aged > 60 years [AHR = 2.93(95% CI: 1.29–6.66)], having diabetic retinopathy [AHR = 2.76(95% CI: 1.84–4.16)], having anemia [AHR = 3.62 (95% CI: 2.46–5.33)], having hypertension [AHR = 3.22(95% CI: 2.10–4.93)], and baseline fasting blood sugar > 200 mg/dl [AHR = 2.56(95% CI: 1.68–3.92)] were the predictors of diabetic neuropathy.ConclusionThe risk of occurrence of diabetic neuropathy among type two diabetes mellitus patients was high in the early period. Age > 60 years, diabetic retinopathy, anemia, baseline fasting blood sugar level > 200 mg/dl, and hypertension were the main predictors of incidence of diabetic neuropathy. Therefore, early detection and appropriate interventions are important for patients with old age, diabetic retinopathy, anemia, hypertension, and FBS > 200mg/dl.
The relationship between loneliness and mobile phone addiction among Chinese college students: The mediating role of anthropomorphism and moderating role of family support
Authors: Zhang Yanhong , Li Yongxue , Xia Meng , Han Miao , Yan Lei , Lian Shuailei 
Published: April 2023

Background
Loneliness and mobile phone addiction are common phenomena in our daily life that can lead to physical and psychological maladaptation. Although loneliness has been considered to be correlated with adolescents’ mobile phone addiction, the underlying mechanisms of the relation between loneliness and mobile phone addiction are still unclear. In order to address the problem of mobile phone addiction among adolescents, the association of loneliness with mobile phone addiction was explored from the perspective of Compensatory Internet Use Theory. The mediating role of anthropomorphism and the moderating role of family support were examined.

Methods
Data were collected through convenience sampling from a comprehensive university in China. A total of 582 Chinese college students (279 men and 303 women), aged from 17 to 24 (Mage = 20.22 years, SD = 1.46), participated in this study. Their loneliness, anthropomorphism, family support and mobile phone addiction were measured using well-validated self-report questionnaires. Regression-based statistical mediation and moderation were conducted using the PROCESS macro for SPSS.

Results
Loneliness was significantly and positively associated with mobile phone addiction, and this link could be mediated by anthropomorphism. Moreover, the direct effect of loneliness on mobile phone addiction and the indirect effect of anthropomorphism in this link were moderated by family support. Both these two effects were stronger for college students with lower family support.

Conclusion
The present study broadened our knowledge of the underlying mechanisms between loneliness and mobile phone addiction. These findings may contribute to a better understanding of the impact loneliness can have on mobile phone addiction as well as its paths. Moreover, the results can also provide advice for parents and constructive suggestions for rationalizing college students’ mobile phone use in the mobile Internet era. Educational professionals and parents should pay special attention to the problem of mobile phone addiction among lonely adolescents, especially for those with low family support.
Of Feral and Obedient Cows
Authors: Bonifacio Valentina 
Published: April 2023

In the Paraguayan Chaco, cattle evoke images of power, prosperity, and celebration, but they also trigger one of the quickest deforestation processes in the world. The presence of cattle in the region has deep historical roots, dating back to the beginning of the colonization process, when the establishment of a double economy based on cattle ranching and the tannin industry dispossessed indigenous people of their territories. Through a historical and ethnographic analysis of the Carlos Casado tannin company, I suggest considering domestication and ferality—and their local related idioms (amansar, anestesiar, sagua’a, señuelo, carne)—as inter-species categories crucial for understanding processes of colonization from a local perspective. In particular, I claim that practices and idioms related to the (un)domestication domain have been used to make sense of ethnic, class, and power relationships, as well as of practices of resistance.

RESUMEN

En el Chaco paraguayo, el ganado bovino evoca imágenes de poder, prosperidad y abundancia. Pero, a la vez, es la causa de uno de los procesos de deforestación más rápidos del mundo. La presencia de ganado en la región tiene profundas raíces históricas y se remonta al principio del proceso de la colonización, cuando el establecimiento de una doble economía basada en la ganadería y la industria del tanino despojó a los pueblos indígenas de sus tierras. A través de un análisis histórico y etnográfico de la compañía taninera Carlos Casado S.A., propongo considerar a la domesticación y a lo asilvestrado—en sus distintas declinaciones: amansar, anestesiar, sagua’a, señuelo, carne—como categorías interespecíficas fundamentales para entender los procesos de colonización desde una perspectiva local. En particular, sostengo que las prácticas y los términos relacionados con el campo semántico de la (de)domesticación fueron utilizados para poner en escena y conceptualizar relaciones étnicas, de clase y de poder, como así también prácticas de resistencia.