bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantum-enhanced receiver for quadrature phase shift keying using conjugated homodyne detection
Authors: Wu Tianyi , Ran Yang , Zhou Zichao , Guo Chang , Li Kai , Dong Chen 
Published: May 2023

AbstractCoherent detection (homodyne detection/heterodyne detection) and single photon detection are commonly applied in classical communication and quantum communication/receiver respectively. In this paper, we firstly propose a quantum-enhanced receiver based on conjugated homodyne detection, which is consisted of two classical balanced homodyne detectors, for discrimination among quadrature-phase-modulated weak coherent states. Our detection part works as a photon counter in every single-shot measurement during the process of detection and feedback, which could help our quantum-enhanced receiver surpass the standard quantum limit when an optimized detection threshold τ from 0.05 to 0.3 is selected. Moreover, our proposed quantum-enhanced receiver with conjugated homodyne detectors can obtain the same low error probability as conventional quantum-enhanced receivers (with its superconducting nanowire single photon detectors’ detection efficiency 60% for pulse separation $M=8$
M
=
8
and 70% for $M=12$
M
=
12
under the same adaptive feedback countermeasures.) Meanwhile, our scheme of the quantum-enhanced receiver gains its incomparable advantages on room-temperature working condition and low cost due to the application of conjugated homodyne detectors. As far as we concerned, this is the first time to explore the performance of the quantum-enhanced receiver with commercial homodyne detectors. And the analysis in this paper may pave the way to reduce the cost of the quantum-enhanced receiver and make it more adaptable for long-distance optical communication systems.
Rigidity of Superdense Coding
Authors: Nayak Ashwin , Yuen Henry 
Published: May 2023

The famous superdense coding protocol of Bennett and Wiesner demonstrates that it is possible to communicate two bits of classical information by sending only one qubit and using a shared EPR pair. Our first result is that an arbitrary protocol for achieving this task (where there are no assumptions on the sender’s encoding operations or the dimension of the shared entangled state) is locally equivalent to the canonical Bennett-Wiesner protocol. In other words, the superdense coding task is
rigid
. In particular, we show that the sender and receiver only use additional entanglement (beyond the EPR pair) as a source of classical randomness.

We also investigate several questions about higher-dimensional superdense coding, where the goal is to communicate one of
d
2
possible messages by sending a
d
-dimensional quantum state, for general dimensions
d
. Unlike the
d
=2 case (i.e., sending a single qubit), there can be inequivalent superdense coding protocols for higher
d
. We present concrete constructions of inequivalent protocols, based on constructions of inequivalent orthogonal unitary bases for all
d
> 2. Finally, we analyze the performance of superdense coding protocols where the encoding operators are independently sampled from the Haar measure on the unitary group. Our analysis involves bounding the distinguishability of random maximally entangled states, which may be of independent interest.
Secondary Migration Trend Based on Basin Modeling: A Case Study of the Cambrian Petroleum System in the Tarim Basin
Authors: Yue Yong , Li Bin , Wei Peng , Zhang Xin , Zhang Kun , Suju Yang , Qingqi Xu 
Published: May 2023

Secondary hydrocarbon migration is an important aspect of oil-gas accumulation research. While previous studies have relied on geological and fluid geochemical characteristics to predict migration direction, these results are often limited by the number of samples. In recent years, basin simulation has emerged as a valuable tool in hydrocarbon migration research due to its extensive algorithms and adaptable modeling capabilities. It has obvious technical advantages especially for resource evaluation in areas with a lower exploration degree and scarce data. The deep oil and gas in the Cambrian petroleum system in the Tarim Basin is a deep hydrocarbon challenging area in China. There has been no breakthrough in exploration due to the large burial depth (

generally
>
6000

m

) and the long accumulation and transformation processes. Therefore, predicting the secondary migration of Cambrian oil and gas has become the key to solving this problem. In this study, first, the thermal evolution of the Lower Cambrian source rocks in the Tarim Basin was recovered, and the three thermal evolution models were developed. The secondary migration process of the Cambrian petroleum system was restored using the geologic model of the source rocks and paleotectonic evolution and the latest fluid potential information. By comparing the simulation results, four secondary migration models of the ultradeep oil-gas migration and accumulation were developed: multisource, multiphase, multidirectional accumulation; multisource, multiphase, single-directional accumulation; single-source, multiphase, multidirectional accumulation; and single-source, multiphase, single-directional accumulation. The fluid potential simulation results indicate that the Cambrian oil and gas have salient inheritance characteristics. The dominant migration channels in the uplift and slope are beneficial to oil-gas migration and accumulation, and the Katake uplift and the west Bachu uplift have multisource charging accumulation. The east Bachu uplift and the Tabei uplift are oil-gas accumulation zones that are beneficial to the lower petroleum system due to the continuous charging of a single petroleum system. This fluid potential simulation provides a new solution for studying the secondary migration of deep oil and gas. It provides an important reference for studying hydrocarbon accumulation in deep and ultradeep areas.
No Princípio, Deus criou: a cosmogonia como estratégia retórica para a reconstrução de laços coletivos nos séculos VI e V AEC
Authors: Onodera Enzo Snitovsky 
Published: May 2023

Neste artigo, analisamos a forma como a tradição profética do Segundo Isaías utiliza o tema da criação como recurso retórico e mnemônico durante a reconstrução da comunidade judaíta no exílio, após as deportações do século VI AEC. Para isso, analisamos inicialmente os estudos sobre os impactos do fenômeno diaspórico na construção de identidades coletivas na Antiguidade. Em seguida, partimos para uma discussão sobre a memória coletiva e seus mecanismos de transmissão entre gerações frente ao trauma e à destruição. Por fim, a partir dos capítulos 43 e 44 de Isaías, analisamos como a profecia recupera e ressignifica o tema da Criação, analisando os possíveis impactos dessa temática na reconstrução dos laços coletivos e representações culturais na diáspora, durante os séculos VI e V AEC.
A Systematic Review of Adverse Events and Complications After Isolated Posterior Medial Meniscus Root Repairs
Authors: Jackson Garrett R. , Warrier Alec A. , Wessels Morgan , Khan Zeeshan A. , Obioha Obianuju , McCormick Johnathon R. , Kaplan Daniel J. , Mameri Enzo S. , Knapik Derrick M. , Verma Nikhil N. , Chahla Jorge 
Published: May 2023

Background: Medial meniscus posterior root (MMPR) tears are recognized as a substantial cause of disability and morbidity. However, meniscus root repair, regardless of technique, is not without potential complications. Purpose: To evaluate the reported incidence of complications and adverse events after isolated MMPR repair. Study Design: Systematic review; Level of evidence, 4. Methods: A systematic review was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines using Embase, PubMed, and Scopus databases with the following search terms combined with Boolean operators: “meniscus,”“root,” and “repair.” Inclusion criteria consisted of level 1 to 4 human clinical studies in English or English-language translation reporting complications and adverse events after isolated posterior medial meniscus root repairs. The overall incidence of specific complications was estimated from the pooled sample of the included studies. Results: Eleven studies with a total pooled sample of 442 patients were identified. The mean patient age was 58.1 years, while the mean final follow-up time was 37.2 months (range, 12-84.8 months). The overall incidence of complications was 9.7% (n = 43/442), with the most commonly reported complication being progressive degenerative changes within the knee (10.4%; n = 25/240; n = 5 studies). A total of 1.25% (n = 3/240) of patients who experienced degenerative changes required conversion to total knee arthroplasty. Repair failures were reported in 3.1% (n = 10/327; n = 8 studies) of patients. Conclusion: Repairing MMPR tears is critical in preventing accelerated progression of knee osteoarthritis in patients without significant knee osteoarthritis preoperatively. While this repair is still recommended and necessary in appropriate patients, this review found that the incidence of complications after isolated posterior medial meniscus root repair was 9.7%, primarily involving the presence of progressive degeneration, while repair failure was reported in 3% of patients.
Increase in traumatic injury burden amidst COVID-19 was disproportionately shouldered by racial and ethnic minority patients: An urban case study
Authors: Tomas CW , Flynn-O’Brien KT , Harris J , Kostelac C , Moore R , Cassidy LD , deRoon-Cassini TA 
Published: May 2023

Background When the COVID-19 pandemic intersected with the longstanding global pandemic of traumatic injury, it exacerbated racial and ethnic disparities in injury burden. As Milwaukee, Wisconsin is a racially diverse yet segregated urban city due to historic and ongoing systemic efforts, this populace provided an opportunity to further characterize injury disparities. Method We analyzed trauma registry data from the only adult Level 1 trauma center in Milwaukee, WI before and during the COVID-19 pandemic ( N = 19,908 patients from 2015–2021). We retrospectively fit seasonal ARIMA models to monthly injury counts to determine baseline injury burden pre-COVID-19 (Jan 2015–Mar 2020). This baseline data was used to forecast injury by race and ethnicity from April 2020 to December 2021 and was compared to actual injury counts. Results For all mechanisms of injury (MOI), counts during the pandemic were significantly higher than forecasted for Black or African American (mean absolute percentage error, MAPE = 23.17) and Hispanic or Latino (MAPE = 26.67) but not White patients (MAPE = 12.72). Increased injury for Black or African American patients was driven by increases in motor vehicle crashes (MVCs) and firearm-related injury; increased injury for Hispanic or Latino patients was driven by falls and MVCs. Conclusions The exacerbation of injury burden disparities during COVID-19, particularly in specific MOI, underscores the need for primary injury prevention within specific overburdened communities. Injury prevention requires intervention through social determinants of health, including addressing the impact of structural racism, as primary drivers of injury burden disparities.
Development of a video-based evidence synthesis knowledge translation resource: Drawing on a user-centred design approach
Authors: Deliv Cristian , Devane Declan , Putnam El , Healy Patricia , Hall Amanda , Rosenbaum Sarah , Toomey Elaine 
Published: May 2023

Objectives We aimed to develop a video animation knowledge translation (KT) resource to explain the purpose, use and importance of evidence synthesis to the public regarding healthcare decision-making. Methods We drew on a user-centred design approach to develop a spoken animated video (SAV) by conducting two cycles of idea generation, prototyping, user testing, analysis, and refinement. Six researchers identified the initial key messages of the SAV and informed the first draft of the storyboard and script. Seven members of the public provided input on this draft and the key messages through think-aloud interviews, which we used to develop an SAV prototype. Seven additional members of the public participated in think-aloud interviews while watching the video prototype. All members of the public also completed a questionnaire on perceived usefulness, desirability, clarity and credibility. We subsequently synthesised all data to develop the final SAV. Results Researchers identified the initial key messages as 1) the importance of evidence synthesis, 2) what an evidence synthesis is and 3) how evidence synthesis can impact healthcare decision-making. Members of the public rated the initial video prototype as 9/10 for usefulness, 8/10 for desirability, 8/10 for clarity and 9/10 for credibility. Using their guidance and feedback, we produced a three-and-a-half-minute video animation. The video was uploaded on YouTube, has since been translated into two languages, and viewed over 12,000 times to date. Conclusions Drawing on user-centred design methods provided a structured and transparent approach to the development of our SAV. Involving members of the public enhanced the credibility and usefulness of the resource. Future work could explore involving the public from the outset to identify key messages in developing KT resources explaining methodological topics. This study describes the systematic development of a KT resource with limited resources and provides transferrable learnings for others wishing to do similar.
Association Between Industry Sponsorship of Spine-Related Clinical Trials, Publication Status, and Research Outcomes
Authors: Munsch Maria A. , Chen Stephen R. , Dalton Jonathan , Tisherman Robert , Shaw Jeremy D. , Lee Joon Y. 
Published: May 2023

Study Design Observational Database Study. Objectives Prospective clinical trials in spinal surgery are expensive to conduct, especially when randomized, appropriately powered, and/or multicentered. Industry collaborations generate symbiotic relationships promoting technological advancement; however, they also allow for bias. To the authors’ knowledge, there is no known analysis of correlations between industry sponsorship and publication rates of spine-related clinical trials. This observational work evaluates such potential associations. Methods The ClinicalTrials.gov database was queried with terms spine, spinal, spondylosis, spondylolysis, cervical, lumbar, and compression fracture over an 11-year period. Design characteristics and outcomes were recorded from 822 spine surgery-related trials. Trials were stratified based on funding source and intervention class. Groups were compared via two-tailed chi-square test of independence or Fisher’s exact test (α = .05), based on completion status and publication rates of positive vs negative results. Results Industry-sponsored spine-related clinical trials were more likely to be terminated than their non-industry-sponsored counterparts (P < .001). Of the trials achieving publication, industry-sponsored trials reported positive results at a higher rate than did trials without industry funding (P = .037). Clinical trials examining devices were more likely to be terminated than those studying other intervention classes (P = .001). Conclusions High termination rates and positive result publication rates among industry-sponsored clinical trials in spinal surgery likely reflect industry’s influence on the research community. Such partnership alleviates financial burden and provides accessibility to cutting-edge innovation. It is essential that all parties remain mindful of the significant bias that funding source may impart on study outcome.
The Role of Lung Ultrasonography Scoring in Predicting the Need for Surfactant Therapy in Neonates, With Respiratory Distress Syndrome
Authors: Nosrati Maryam , Akhoundi Neda , Ahmadzadeh Nanva Amir Hasan , Siami Alireza , Khoshnoud Shariati Maryam , Rezazadeh Elmira , Khalili Pouya Ensi 
Published: May 2023

Objective: Surfactant administration has an essential role in the treatment of neonatal respiratory distress syndrome (RDS). This is coupled with the capability of a lung sonography scoring system (LUS scoring) in assessing neonatal lungs with RDS, makes evaluating the role of such a scoring system important in deciding to use surfactant therapy. Materials and Methods: This cross-sectional study was conducted on neonates with RDS, at a gestational age of more than 30 weeks. Using a high-frequency ultrasound transducer, neonates’ results were assessed by a radiologist, and then LUS scoring was determined in both groups, with and without the need for surfactant therapy. Results: The mean LUS scoring in the two groups was 9.08 ± 3.09 and 4.12 ± 2.56, respectively, which indicated a significant difference. The LUS scoring had a higher ability to predict the need for surfactant treatment, based on a receiver operating curve analysis. The best diagnostic cutoff point, for LUS scoring in predicting the need for surfactant treatment, was 6 in neonates 30–32 weeks and 7 in neonates 32–34 weeks. The use of LUS scoring had a sensitivity of 85.1%, 84% and a specificity of 87.2%, 88%, respectively. Conclusion: The LUS scoring may be used to help in the predicted need for surfactant therapy, in neonates with RDS.
scRNASequest: an ecosystem of scRNA-seq analysis, visualization, and publishing
Authors: Li Kejie , Sun Yu H. , Ouyang Zhengyu , Negi Soumya , Gao Zhen , Zhu Jing , Wang Wanli , Chen Yirui , Piya Sarbottam , Hu Wenxing , Zavodszky Maria I. , Yalamanchili Hima , Cao Shaolong , Gehrke Andrew , Sheehan Mark , Huh Dann , Casey Fergal , Zhang Xinmin , Zhang Baohong 
Published: May 2023

Abstract
Background
Single-cell RNA sequencing is a state-of-the-art technology to understand gene expression in complex tissues. With the growing amount of data being generated, the standardization and automation of data analysis are critical to generating hypotheses and discovering biological insights.

Results
Here, we present scRNASequest, a semi-automated single-cell RNA-seq (scRNA-seq) data analysis workflow which allows (1) preprocessing from raw UMI count data, (2) harmonization by one or multiple methods, (3) reference-dataset-based cell type label transfer and embedding projection, (4) multi-sample, multi-condition single-cell level differential gene expression analysis, and (5) seamless integration with cellxgene VIP for visualization and with CellDepot for data hosting and sharing by generating compatible h5ad files.

Conclusions
We developed scRNASequest, an end-to-end pipeline for single-cell RNA-seq data analysis, visualization, and publishing. The source code under MIT open-source license is provided at https://github.com/interactivereport/scRNASequest. We also prepared a bookdown tutorial for the installation and detailed usage of the pipeline: https://interactivereport.github.io/scRNAsequest/tutorial/docs/. Users have the option to run it on a local computer with a Linux/Unix system including MacOS, or interact with SGE/Slurm schedulers on high-performance computing (HPC) clusters.
Excessive salt intake accelerates the progression of cerebral small vessel disease in older adults
Authors: Liu Di , Zhang Qin , Xing Shasha , Wei Fang , Li Ke , Zhao Yingxin , Zhang Hua , Gong Gary , Guo Yuqi , Liu Zhendong 
Published: May 2023

Abstract
Background
It is unclear whether excessive salt intake accelerates the progression of cerebral small vessel disease (CSVD). The major objective of this study was to investigate the harmful effect of excessive salt intake on the progression of CSVD in older individuals.

Methods
Between May 2007 and November 2010, 423 community-dwelling individuals aged 60 years and older were recruited from the Shandong area, China. Salt intake was estimated using 24-hour urine collection for 7 consecutive days at baseline. Participants were classified into low, mild, moderate and high groups according to the salt intake estimation. CSVD including white matter hyperintensities (WMHs), lacunes, microbleeds and an enlarged perivascular space (EPVS) were determined using brain magnetic resonance imaging.

Results
During an average of five years of follow-up, the WMH volume and WMH-to-intracranial ratio were increased in the four groups. However, the increasing trends in the WMH volume and WMH-to-intracranial ratio were significantly faster in the higher salt intake groups compared with the lower salt intake groups (Padjusted < 0.001). The cumulative hazard ratios of new-incident WMHs (defined as those with Fazekas scale scores ≥ 2), new-incident lacunes, microbleeds or an EPVS, as well as composites of CSVD, were respectively 2.47, 2.50, 3.33, 2.70 and 2.89 for the mild group; 3.72, 3.74, 4.66, 4.01 and 4.49 for the moderate group; and 7.39, 5.82, 7.00, 6.40 and 6.61 for the high group, compared with the low group after adjustment for confounders (Padjusted < 0.001). The risk of new-incident WMHs, lacunes, microbleeds or an EPVS, and composites of CSVD was significantly increased with each 1-standard-deviation increment in salt intake (Padjusted < 0.001).

Conclusion
Our data indicates that excessive salt intake is an important and independent contributor to the progression of CVSD in older adults.
Gitelman syndrome with Graves’ disease leading to rhabdomyolysis: a case report and literature review
Authors: Xu Jing , He Juan , Xu Shujing , Wang Rui , Peng Nianchun , Zhang Miao 
Published: May 2023

AbstractA 14-year-old male patient who suffered from limb numbness, fatigue, and hypokalemia was considered Graves’ disease (GD) complicated with thyrotoxic periodic paralysis (TPP) at the first diagnosis. Although with the treatment of antithyroid drugs, he developed severe hypokalemia and rhabdomyolysis (RM). Further laboratory tests revealed hypomagnesemia, hypocalciuria, metabolic alkalosis, hyperrenin, and hyperaldosteronemia. Genetic testing revealed compound heterozygous mutations in the SLC12A3 gene (c.506-1G > A, c.1456G > A) encoding the thiazide-sensitive sodium-chloride cotransporter, which presented a definitive diagnosis of Gitelman syndrome (GS). Moreover, gene analysis revealed his mother diagnosed with subclinical hypothyroidism due to Hashimoto’s thyroiditis carried the c.506-1G > A heterozygous mutation in the SLC12A3 gene and his father carried the c.1456G > A heterozygous mutation in the SLC12A3 gene. His younger sister who had hypokalemia and hypomagnesemia carried the same compound heterozygous mutations as the proband and was diagnosed with GS as well, but with a much milder clinical presentation and better treatment outcome. This case suggested the potential relationship between GS and GD, clinicians should strengthen the differential diagnosis to avoid missed diagnosis.