bluuebunny/crossref_metadata_2025_split huggingface dataset:
Idiopathic Isolated Adrenocorticotropic Hormone Deficiency: A
Single-Center Retrospective Study
Authors: Yang Chengyan , Li Xinpei , Ma Xiaoqing 
Published: September 2023

AbstractIdiopathic isolated adrenocorticotrophic hormone deficiency (IIAD) is rare, with
high clinical omission and misdiagnosis rates. This study retrospectively
collected information on clinical presentation, laboratory findings, and
treatment response of 17 patients with IIAD at Jining No. 1 People's
Hospital from January 2014 to December 2022. The clinical characteristics were
summarized, and the pertinent data were analyzed. As a result, most of the
patients with IIAD were male (94.12%), with age at onset ranging from 13
to 80 years. The primary manifestations were anorexia (88.24%), nausea
(70.59%), vomiting (47.06%), fatigue (64.71%), and
neurological or psychiatric symptoms (88.24%). The median time to
diagnosis was 2 months and the longest was 10 years. Laboratory tests mostly
showed hyponatremia (88.24%) and hypoglycemia (70.59%). The
symptoms and laboratory indicators returned to normal after supplementing
patients with glucocorticoids. IIAD has an insidious onset and atypical
symptoms; it was often misdiagnosed as gastrointestinal, neurological, or
psychiatric disease. The aim of this study was to improve clinicians'
understanding of IIAD, patients with unexplained gastrointestinal symptoms,
neurological and psychiatric symptoms, hyponatremia, or hypoglycemia should be
evaluated for IIAD and ensure early diagnosis and treatment.
StäB oder Station? – Erste Ergebnisse zur
Studienpopulation und zur Behandlung im Rahmen der multizentrischen AKtiV-Studie
zur stationsäquivalenten Behandlung
Authors: Nikolaidis Konstantinos , Weinmann Stefan , von Peter Sebastian , Längle Gerhard , Brieger Peter , Timm Jürgen , Waldmann Tamara , Fischer Lasse , Raschmann Svenja , Schwarz Julian , Holzke Martin , Rout Sandeep , Hirschmeier Constance , Hamann Johannes , Herwig Uwe , Richter Janina , Baumgardt Johanna , Bechdolf Andreas 
Published: September 2023

Zusammenfassung
Ziel Die quasi-experimentelle AKtiV-Studie untersucht die Wirksamkeit der
stationsäquivalenten Behandlung (StäB). Diese Arbeit beschreibt
die demographischen und klinischen Parameter der Teilnehmenden zum
Studieneinschluss und vergleicht deren Indexbehandlungen.
Methodik Über einen Zeitraum von 12 Monaten wurden 200
StäB-Nutzende in die Interventionsgruppe (IG) und 200 stationär
behandelte Personen in die Kontrollgruppe (KG) eingeschlossen. Die
Vergleichbarkeit der beiden Gruppen wurde mittels Propensity-Score Matching
(PSM) Verfahren sichergestellt.
Ergebnisse Zusätzlich zu den PSM-Variablen unterschieden sich alle
weiteren erhobenen Charakteristika zwischen der Interventionsgruppe (IG) und der
Kontrollgruppe (KG) zum Zeitpunkt der Studieneinschreibung nicht signifikant
voneinander. Die Dauer der Indexbehandlung war in der IG signifikant
länger (M=37,2 Tage) als in der KG (M=27,9 Tage;
p<0,001).
Schlussfolgerung Die Ähnlichkeit der beiden Gruppen erlaubt einen
Vergleich und somit die Untersuchung der Auswirkungen von StäB auf
längerfristige Outcomes.
Human Papillomavirus 16 Lineage D is Associated with High Risk of Cervical Cancer in the Brazilian Northeast Region
Authors: Martins Luís Felipe Leite , Moreira Miguel Ângelo Martins , Pinto Rodrigo Alves , Reis Neilane Bertoni dos , Felix Shayany Pinto , Vidal João Paulo Castello Branco , Torres Leuridan Cavalcante , Souza Ariani Impieri , Almeida Liz Maria de 
Published: September 2023

Abstract
Objective Similar to Human Papillomavirus (HPV) genotypes, different lineages of a genotype also have different carcinogenic capabilities. Studies have shown that specific genotype lineages of oncogenic HPV are associated with variable risks for the development of cervical intraepithelial neoplasia (CIN2/CIN3) and cervical cancer. The present study aimed to analyze the genetic diversity of the HPV16 genotype in women with CIN2/CIN3 and cervical cancer, from the northeast region of Brazil.
Methods A cross-sectional multicenter study was conducted in the northeast region of Brazil, from 2014 to 2016. This study included 196 cases of HPV16 variants (59 and 137 cases of CIN2/CIN3 and cervical cancer, respectively). The difference of proportion test was used to compare patients with CIN2/CIN3 and cervical cancer, based on the prevalent HPV16 lineage (p < 0.05).
Results According to the histopathological diagnosis, the percentage of lineage frequencies revealed a marginal difference in the prevalence of lineage A in CIN2/CIN3, compared with that in cervical cancer (p = 0.053). For lineage D, the proportion was higher in cancer cases (32.8%), than in CIN2/CIN3 cases (16.9%), with p = 0.023.
Conclusion HPV16 lineage A was the most frequent lineage in both CIN2/CIN3 and cervical cancer samples, while lineage D was predominant in cervical cancer, suggesting a possible association between HPV16 lineage D and cervical cancer.
Reproductive Planning and the Choice of Long-acting Reversible Contraceptive Primary to Health: A Cross-Sectional Study
Authors: Brufatto João Paulo Turri , Dias Thais Machado , D'abreu Natália Bortoletto , Rehder Patricia Moretti 
Published: September 2023

Abstract
Objective Evaluate the different perspectives that involve the choice of long-acting reversible contraceptives (LARCs), the issues related to this process and the consequences of deciding one method in the women's in the primary health care (PHC) center in Sousas, a district in Campinas, SP (Brazil).
Methods This is an analytical cross-sectional study, it was performed at the PHC in Sousas. Data were collected through the analysis of medical records and interviews with women who live in Sousas and had the insertion of the copper intrauterine device (IUD) (D) from April 2021 to April 2022 or the etonogestrel implant (I) from May to December 2022. The study was approved by the Research Ethics Committee of the Medical Science School at the State University of Campinas (UNICAMP).
Results Reason for choosing this LARC: medical (D: 52%; I: 100%), easy adhesion (D: 71%; I: 67%), effectiveness (D: 55%; I: 100%). Indication by health professionals (D: 65%; I: 100%). And improvement of clinical characteristics: mood (D: 77%; I: 67%), body mass index (BMI; D: 52%; I: 33%), and libido (D: 84%; I: 67%).
Conclusion It is suggested that women tend to decide between LARCs when guided by their doctor or PHC health professionals, and they select LARCs because of the ease of use and low failure rates. Therefore, this study highlights how LARCs can positively interfere in the aspects that pervade contraception, such as BMI, libido, and mood.
Ab initio potential energy surfaces for the O2–O2 system and derived thermophysical properties
Authors: Hellmann Robert 
Published: September 2023

New intermolecular potential energy surfaces (PESs) for the quintet, triplet, and singlet states of two rigid oxygen (O2) molecules in their triplet ground electronic states were developed. Quintet interaction energies were obtained for 896 O2–O2 configurations by supermolecular coupled cluster (CC) calculations at levels up to CC with single, double, triple, and perturbative quadruple excitations [CCSDT(Q)] with unrestricted Hartree–Fock (UHF) reference wave functions. Corrections for scalar relativistic effects were calculated as well. Triplet interaction energies were obtained by combining the quintet interaction energies with accurate estimates for the differences between the quintet and triplet energies obtained at the UHF-CCSD(T) level of theory. Here, we exploited the fact that the triplet state is almost identical to the readily accessible “broken-symmetry” state, as shown by Valentin-Rodríguez et al. [J. Chem. Phys. 152, 184304 (2020)]. The singlet interaction energies were estimated from the quintet and triplet interaction energies by employing the Heisenberg Hamiltonian description of the spin splittings. The three PESs are represented analytically by site–site models with five sites per molecule and anisotropic site–site interactions. To validate the PESs, we calculated at temperatures from 55 to 2000 K the second virial coefficient using statistical thermodynamics and the shear viscosity, thermal conductivity, and self-diffusion coefficient in the dilute gas phase using the kinetic theory of molecular gases. The calculated property values are in excellent agreement with the most accurate experimental data from the literature. Therefore, we also propose new reference correlations for the investigated properties based solely on the calculated values.
Smooth and oscillatory geometric phase corrections for driven spins
Authors: Berry M V 
Published: September 2023

Abstract
For a quantum spin driven cyclically by a slowly-rotated magnetic field, geometric phases are well understood. If the cycle takes a long time

T
,

the leading-order (dynamical) phase is proportional to

T

and the geometric phase is the contribution independent of

T
.

The dynamical and geometric phases are the first two terms of a series in slowness

1
/
T
.

Here it is shown with an exactly solvable example that the corrections are of two types: smooth, proportional to powers of slowness, and oscillatory: essential singularities in

1
/
T
,

in the form of trigonometric functions of

T

divided by powers of

T
.

The calculations are elementary and therefore suitable for presentation in graduate quantum theory courses.
An empirical potential for simulating hydrogen isotope retention in highly irradiated tungsten
Authors: Mason Daniel R , Nguyen-Manh Duc , Lindblad Victor W , Granberg Fredric G , Lavrentiev Mikhail Yu 
Published: September 2023

Abstract
We describe the parameterization of a tungsten-hydrogen empirical potential designed for use with large-scale molecular dynamics simulations of highly irradiated tungsten containing hydrogen isotope atoms, and report test results. Particular attention has been paid to getting good elastic properties, including the relaxation volumes of small defect clusters, and to the interaction energy between hydrogen isotopes and typical irradiation-induced defects in tungsten. We conclude that the energy ordering of defects changes with the ratio of H atoms to point defects, indicating that this potential is suitable for exploring mechanisms of trap mutation, including vacancy loop to plate-like void transformations.
Photoelectric performance of InSe vdW semi-floating gate p–n junction transistor
Authors: Wang Jinghui , Wang Yipeng , Feng Guojin , Zeng Zhongming , Ma Tieying 
Published: September 2023

Abstract
Semi-floating gate transistors based on vdW materials are often used in memory and programmable logic applications. In this paper, we propose a semi-floating gate photoelectric p–n junction transistor structure which is stacked by InSe/h-BN/Gr. By modulating gate voltage, InSe can be presented as N-type and P-type respectively on different substrates, and then combined into p–n junction. Moreover, InSe/h-BN/Gr device can be switched freely between N-type resistance and p–n junction. The resistance value of InSe resistor and the photoelectric properties of the p–n junction are also sensitively modulated by laser. Under dark conditions, the rectification ratio of p–n junction can be as high as 107. After laser modulation, the device has a response up to 1.154 × 104 A W−1, a detection rate up to 5.238 × 1012 Jones, an external quantum efficiency of 5.435 × 106%, and a noise equivalent power as low as 1.262 × 10−16 W/Hz1/2. It lays a foundation for the development of high sensitivity and fast response rate tunable photoelectric p–n junction transistor.
Thermodynamic geometry of STU black holes
Authors: Sekhmani Yassine , Gogoi Dhruba Jyoti , Baouahi Mourad , Dahiri Imane 
Published: September 2023

Abstract
This work investigates the phase structure of STU black holes with uniform charges by utilizing the New Thermodynamic Geometry (NTG) approach. The study explores the intriguing relationship between heat capacity phase transitions and curvature singularities, employing the NTG formalism. The analysis encompasses an examination of phase transitions along the T − S and Q − Φ planes, a study of critical exponents, and an assessment of black hole stability. The NTG geometry is applied in both the normal and extended phase spaces, revealing valuable insights into the thermodynamic behavior and stability of STU black holes. Meanwhile, a closer examination of NTG geometry shows a positive correlation in the sign between the extrinsic curvature and the heat capacity, which is incompatible with the curvature singularity. Overall, this study contributes to our understanding of the phase transitions and thermodynamic properties of STU black holes, shedding light on the intricate interplay between curvature singularities and the stability of black holes in diverse thermodynamic scenarios.
Investigation of the effects of Cu layer thickness and annealing temperature under air atmosphere on the properties of Co/Cu multilayer films
Authors: Karpuz Ali , Köçkar Hakan , Kaplan Nadir 
Published: September 2023

Abstract
In this study, the suitability of Co/Cu multilayer films with different physical conditions (varying thickness values and systematic annealing processes) in magnetic technology applications is discussed. Co/Cu films were deposited by the sputtering technique. The effects of different thicknesses of non-magnetic (Cu) layers and annealing temperature on magneto-structural properties were investigated. Different thicknesses of Cu layers were determined as 34 nm, 10 nm, 4 nm. Additionally, two annealed situations were considered to investigate the annealing effect. While the first one is exposing the films to 80 °C and 130 °C for 240 s, second one is annealing the films at 180 °C for different exposure times (50 s and 150 s). All films that have different thicknesses of Cu layers crystallized in (111) plane of the face centered cubic (fcc) structure. The intensity of this peak increased with increasing Cu layers thickness. Variation in the thickness of Cu layers has an important effect on the film surface. Saturation magnetization (Ms), coercivity (Hc) and squareness (Mr/Ms, Mr: remanent magnetization) were considerably affected by variation of the Cu content and film surface caused by the change in the thickness of the Cu layers. The film with 4 nm Cu layer thickness has the highest Ms, lowest Hc values and high Mr/Ms ratio. This indicates magnetically high efficient compared to the other films in the same series. The fcc structure continued to exist for the films annealed at 80 °C and 130 °C for 240 s. It was found that the annealing procedure transfigured the film surface and the differences in Ms and Hc values can be mostly attributed to this transfiguration because of the same film content revealed. An increase in Ms value, and a slight decrease in Hc and Mr/Ms values were detected for the annealed film at 130 °C, compared to the film annealed at 80 °C. It was also seen that the film structure was damaged at 180 °C because of excessive heat transfer.
Surface morphology and topography evolution of soda-lime silica glass after 1.0 MeV Si ion bombardment
Authors: Cruz-Garcia C F , Rickards J , Garcia M A , de la Vega L R , Cañetas-Ortega J , Morales-Morales J G , Rodríguez-Fernández L 
Published: September 2023

Abstract
Surface pattern formation on soda-lime silica glass by 1 MeV Si ion irradiation impinging at an angle of 70° with respect to the surface normal has been studied. Modification of surfaces were analyzed for total ion fluences applied between

1
×

10

17

up to

4
×

10

17

ions/cm2. The surface morphology and topography were studied by scanning electron microscopy (SEM), and atomic force microscopy (AFM). These surface techniques enabled the determination of roughness, characteristic wavelengths, and correlation lengths. In addition, electron dispersive spectroscopy (EDS) scans were applied on the surface topography to study the variation of the Si content on the obtained surface patterns. From the measurement of these variables, linear and non-linear regimes were established. At linear regime, the surface morphology develops from an initial flat surface giving rise to ripples for fluences up to

1.4
×

10

17

ions/cm2. As the ion bombardment continues surface evolve into wrinkles finalizing at cellular-like structures, growing under an anomalous scaling process. The EDS scans indicate the presence of shadowing effects. The morphological changes observed can be explained in terms of a combination of thermal mass diffusion and geometrical factors during ion irradiation, including shadowing and subsequent (secondary) surface erosion effects adapted to few MeV energies.
Simulation of a multi-floor evacuation with the extended social force model in a multi-corridor environment
Authors: Jun Hu , Qi Zhang , Ling Fan , Yifan Liu , Longcheng Yang , Juan Wei 
Published: September 2023

Abstract
For the stagnation problem that easily occurs in the process of simulating multi-floor and multi-staircase evacuation using a traditional social force model, in this paper, it is proposed to improve the social force model by introducing a moth-flame optimization algorithm, thus to establish a new evacuation model. The model firstly integrates the field model into a social force model as the pedestrian self-driving direction. Meanwhile, an objective optimization function of minimum system evacuation time is established based on the evaluation indexes, such as staircase congestion degree and average velocity, and the moth-flame optimization algorithm is improved by introducing dynamic inertia weight and random reverse learning strategy, thus establishing an evacuation optimization method. Finally, a simulation and numerical analysis is carried out for the multi-floor evacuation process using the experimental simulation platform built, which deeply analyzes the key factors influencing the model, gives the change relationships among the parameters such as evacuation time, initial pedestrian velocity, the number of pedestrians and staircase width, and verifies the effectiveness of the model.
Influence of external current and noise on modes of electrical activities and energy of Hindmarsh-Rose model coupled by memristive synapses
Authors: Nando Tezoh Franky Kevin , Adamou Dang Koko , Ekobena Fouda H P 
Published: September 2023

Abstract
The progress of medicine and biological have lengthen life, thus increasing the incidence of degenerative illnesses such as Parkinson, Alzheimer. To help patients suffering from those illnesses, we can use a therapy technique which consists to deliver within a precise region of the central nervous system an electrical signal in order to regulate unnatural impulses. That therapeutic method, since it requires surgical procedure is only needed when medication stops to have effect on the patients. In this work, we study the effects of periodic external current and noise on the modes of electrical activities; Furthermore we estimate the energy of a 2D Hindmarsh-Rose coupled by memristive synapses. Results show that the neuronal network exhibits bursting regime in the presence of periodic external force and noise. Noises make those bursts irregular over time evolution. Concerning the energy analysis, we observe an increase of the energy when the amplitude of the external force increases. Lastly, we show that noise makes the energy of the neuronal network to oscillate with different amplitudes. Large amplitude is observed in the presence of large values of the amplitude of the noise.
Gating and photogalvanic effect tuning the spin transport in single chromium porphyrin from first principles
Authors: Wu Huijie , Liu Xiaojie , Feng Lifeng , Yin Haitao 
Published: September 2023

Abstract
Magnetic molecules are of crucial importance for miniaturizing future spintronic devices. In this work, we investigated the possibility of modulating spin transport in a single chromium porphyrin molecule using the gate voltage and the photogalvanic effect. It was found that, under a certain bias voltage, the gate voltage can effectively regulate the spin filtering effect. Moreover, when the molecule is asymmetrically connected to two gold nanowire electrodes, fully polarized and even pure spin currents can be generated under the irradiation of linearly polarized light. Our findings offer potential pathways for designing single-molecule spintronics and optoelectronic devices.
Deep learning-based prediction of delamination growth in composite structures: bayesian optimization and hyperparameter refinement
Authors: Demircioğlu Ufuk , Bakır Halit 
Published: September 2023

Abstract
In this study, a novel method for detecting the growth of delamination in sandwich structures has been proposed. To this end, we suggested hybridizing the Deep Learning techniques (DL) and Finite Element Method (FEM) for predicting the growth of delamination in this structures. A dataset of simulated delamination growth under different delamination sizes has been produced using the FEM method. Then, a DL model has been trained using this dataset to precisely predict the growth of delamination. This study focused on predicting delamination growth using a tuned and optimized deep learning based regressor. Therefore, to find the ideal set of hyperparameters, the Bayesian optimization algorithm has been used for selecting the best structure and enhancing the regressor performance. Afterward, the model was evaluated and multiple processes were conducted to improve its behavior and solve its stability and overfitting issues. Particularly, an inconsistency between validation loss and training loss has been initially detected in the behaviour of the model, which may indicate overfitting. To tackle this issue, dropout regularization has been added, which improved the consistency between the loss functions but results in less smooth convergence from the expectations. So, in a third study, dropout and L1 regularization has been combined to improve the stability of the model. This combination achieved a consistent and smooth convergence between the validation and training loss functions. The findings highlight the importance of hyperparameter optimization and regularization techniques in improving regression model performance. The study shows the efficiency of Bayesian optimization in hyperparameter tuning and the iterative optimization of a regression model. Furthermore, the outcomes show that the suggested method can identify and predict delamination growth with high accuracy.
CeO2@CuS@PDA-FA as targeted near-infrared PTT/CDT therapeutic agents for cancer cells
Authors: Zhang Jing , Hu Miaomiao , Wen Changchun , Liu Jian , Yu Fang , Long Juan , Lin Xiang-Cheng 
Published: September 2023

Abstract
Single tumor treatment method usually has some defects, which makes it difficult to achieve good therapeutic effect. The ingenious combination of multiple tumor treatment methods on a single nanoplatform to achieve multifunctional treatment can effectively improve the efficiency of treatment. The targeted modification of nanomaterials can augment the precision of nanotherapeutic drugs in tumor treatment. Herein, a multifunctional nanoplatform (CeO2@CuS@PDA-FA) based on cerium dioxide nanoparticles engineered with copper sulfide (CeO2@CuS) has been constructed for synergistic photothermal therapy (PTT) and chemodynamic therapy (CDT). The CeO2@CuS were coated using polydopamine (PDA), and the modification of PDA surface by folic acid, in order to achieve the targeted effect for tumors. The localized hyperthermia induced by PTT can further improve the CDT efficiency of the nanoplatform, leading to a PTT/CDT synergistic effect. The nanoplatform possessed the capability of cancer cell-targeted and achieved better therapeutic efficacy in vitro. This work provided a new strategy for combined multifunctional theranostic platform and shows strong potential in practical applications.