bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compression hemostasis using fully covered self-expandable metallic stents for refractory hemorrhages caused by esophageal cancer: A pilot study
Authors: Bi Yonghua , Ren Jianzhuang , Han Xinwei 
Published: February 2023

ObjectiveFully covered self-expandable metallic stents (SEMSs) have been widely used as a salvage therapy for patients with esophageal variceal bleeding. However, the role of fully covered SEMSs in the management of hemorrhage caused by esophageal cancer has not yet been established. We aimed to investigate the safety and efficacy of fully covered SEMSs as a salvage therapy for esophageal cancer-related hemorrhage.MethodsFrom September 2019 to March 2022, 17 patients, who underwent the insertion of fully covered SEMS for malignant esophageal hemorrhages, were retrospectively analyzed. Chest computed tomography (CT) scans and esophagographies were performed routinely to determine the location and length of the tumor. A fully covered SEMS was implanted under fluoroscopy. Baseline demographics were retrospectively collected, that is those for sex, age, previous treatment, comorbidities, lesion type, and stent size.ResultsA total of 20 metal stents were placed in 17 patients, with a technical success rate of 100% and a hemostasis success rate of 88.2%. Stent removal was performed in three patients because of complications. No perioperative deaths were related to stent placement or removal. Five main complications (29.4%) were found after stent insertion. Stent migration and restenosis were observed in two patients (11.8%). Except for two perioperative deaths and one patient lost to follow-up, all remaining 14 patients were successfully followed up. At the end of follow-up, two patients had survived without obvious symptoms, and a total of 12 patients were dead owing to tumor progression (n = 10), severe infection (n = 1), and cerebrovascular accident (n = 1). The median overall survival was 13.8 months.ConclusionInsertion of a fully covered SEMS may be a safe and effective means of the salvage management of refractory esophageal cancer-related hemorrhage, and its use in this context may lead to the development of innovative methods for compression hemostasis. However, further study with a larger sample size and comparison with other forms of salvage therapy.
C9 immunostaining as a tissue biomarker for periprosthetic joint infection diagnosis
Authors: Meinshausen Ann-Kathrin , Färber Jacqueline , Illiger Sebastian , Macor Paolo , Lohmann Christoph H. , Bertrand Jessica 
Published: February 2023

BackgroundCulture-negative periprosthetic joint infections (PJI) are often false diagnosed as aseptic implant failure leading to unnecessary revision surgeries due to repeated infections. A marker to increase the security of e PJI diagnosis is therefore of great importance. The aim of this study was to test C9 immunostaining of periprosthetic tissue as a novel tissue-biomarker for a more reliable identification of PJI, as well as potential cross-reactivity.MethodWe included 98 patients in this study undergoing septic or aseptic revision surgeries. Standard microbiological diagnosis was performed in all cases for classification of patients. Serum parameters including C-reactive protein (CRP) serum levels and white blood cell (WBC) count were included, and the periprosthetic tissue was immunostained for C9 presence. The amount of C9 tissue staining was evaluated in septic versus aseptic tissue and the amount of C9 staining was correlated with the different pathogens causing the infection. To exclude cross-reactions between C9 immunostaining and other inflammatory joint conditions, we included tissue samples of a separate cohort with rheumatoid arthritis, wear particles and chondrocalcinosis.ResultsThe microbiological diagnosis detected PJI in 58 patients; the remaining 40 patients were classified as aseptic. Serum CRP values were significantly increased in the PJI cohort. Serum WBC was not different between septic and aseptic cases. We found a significant increase in C9 immunostaining in the PJI periprosthetic tissue. To test the predictive value of C9 as biomarker for PJI we performed a ROC analyses. According to the Youden’s criteria C9 is a very good biomarker for PJI detection with a sensitivity of 89% and a specificity of 75% and an AUC of 0.84. We did not observe a correlation of C9 staining with the pathogen causing the PJI. However, we observed a cross reactivity with the inflammatory joint disease like rheumatoid arthritis and different metal wear types. In addition, we did not observe a cross reactivity with chondrocalcinosis.ConclusionOur study identifies C9 as a potential tissue-biomarker for the identification of PJI using immunohistological staining of tissue biopsies. The use of C9 staining could help to reduce the number of false negative diagnoses of PJI.
Third COVID-19 vaccine dose for people with multiple sclerosis who did not seroconvert following two doses of BBIBP-CorV (Sinopharm) inactivated vaccine: A pilot study on safety and immunogenicity
Authors: Sedaghat Nahad , Etemadifar Masoud , Lotfi Noushin , Sayahi Farnaz , Chitsaz Ahmad , Salari Mehri , Ghasemi Movaghar Alireza 
Published: February 2023

BackgroundPeople with multiple sclerosis (pwMS) on anti-CD20 therapies (aCD20) and fingolimod have shown inadequate humoral responses to COVID-19 vaccines.ObjectiveThe objective of the study was to pilot larger studies by demonstrating the safety and comparing the immunogenicity of different types of third doses in seronegative pwMS after two doses of BBIBP-CorV inactivated vaccine.MethodsIn December 2021, subject to receiving their third dose, being COVID-19-naiive, and receiving no corticosteroid within two months, we measured the level of anti-SARS-CoV-2-Spike IgG in pwMS seronegative after two shots of BBIBP-CorV inactivated vaccine.ResultsWe included 20/29 pwMS who received adenoviral vector (AV), 7/29 who received inactivated, and 2/29 who received conjugated third doses. No serious adverse events were reported two weeks post-third dose. The pwMS receiving AV third doses showed significantly increased IgG concentrations, while only the ones not on aCD20 and fingolimod responded to inactivated third doses. An ordinal logistic multivariable generalized linear model indicated that age (per year β: −0.10, P = 0.04), type of disease-modifying therapy (aCD20 β: −8.36, P &lt;0.01; fingolimod β: −8.63, P = 0.01; others: reference), and type of third dose (AV or conjugated β: 2.36, P = 0.02; inactivated: reference) are predictive of third dose immunogenicity among pwMS who remain seronegative after two shots of BBIBP-CorV vaccine. Statistical significance was not achieved for variables sex, MS duration, EDSS, duration of DMT, duration of third dose to IgG test, and duration from last aCD20 infusion to third dose.ConclusionThis preliminary pilot study highlights the need for further research to determine the optimal COVID-19 third dose vaccination strategy for pwMS living in areas where BBIBP-CorV vaccine has been used.
An ultra-high performance concrete incorporating viscosity-controlling agent: Fiber distribution and microstructure
Authors: Zhao Baojun , Zhang Zongjun , Wu Chen , Zou Changgen , Xu Xin , Yang Han , Zhang Wenqi 
Published: February 2023

In order to realize the stability of steel fiber inside ultra-high performance Concrete (UHPC) under vibration and improve the use efficiency of fiber, bentonite is used as auxiliary cementitious material in this study. The influence of bentonite dosage on the mechanical properties of UHPC matrix and the mechanical properties and microstructure of ultra-high Performance fiber Reinforced Concrete (UHPFRC) is explored. On this basis, the functional relationships between the distribution and orientation of steel fibers, the freshness of the matrix and the rheological parameters of UHPC are established, and the evaluation model of the service efficiency of steel fibers is established. The results show that with the gradual increase of bentonite incorporation, the use efficiency of UHPFRC steel fiber increases first and then decreases, and when the cement content of bentonite was 2.5%, 5.0%, 7.5% and 10.0%, the flexural strength of UHPFRC increased by 9.0%, 17.6%, 18.5% and 6.1%, respectively. In addition, the increase of bentonite content will lead to the continuous decrease of the fluidity of fresh UHPC slurry (from 261 mm to 100 mm). When the bentonite content is 10.0%, the UHPC slurry has almost no fluidity (100 mm), which leads to the appearance of pores in the UHPC matrix and the decrease of compressive strength.
Efficacy of photodynamic therapy in the treatment of port wine stains: A systematic review and meta-analysis
Authors: Wang Ling , Li Lei , Huang Chao 
Published: February 2023

BackgroundPort wine stains (PWS) often cause cosmetic effects and psychological distress. Pulsed dye lasers (PDL) and photodynamic therapy (PDT) are the most commonly used treatments. PDL is still the “gold standard” of therapy to date. However, its shortcomings have become apparent as clinical applications have increased. PDT has been proven as an alternative to PDL. Patients with PWS still lack enough evidence about PDT to make informed treatment decisions.ObjectiveThe purpose of this systematic review and meta-analysis was to assess the safety and effectiveness of PDT for PWS.MethodsThe online datasets, comprising PubMed, Embase, Web of Science, and the Cochrane Library, were searched for meta-analysis-relevant publications. Two reviewers separately evaluated the risk of bias in each listed study. Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the treatment and safety outcomes.ResultsOur search retrieved 740 hits and only 26 studies were finally included. Among the 26 studies included, 3 were randomized clinical trials, and 23 were prospective or retrospective cohort investigations. Based on a gathered assessment, the percentage of individuals achieving a 60% improvement was estimated to be 51.5% [95% confidence interval (CI): 38.7–64.1; I2 = 83.8%] and a ≥75% improvement was 20.5% (95% CI: 14.5–26.5; I2 = 78.2%) after 1–8.2 treatment sessions (GRADE score: very low). Due to the statistical diversity of the meta-analysis, a subgroup assessment was performed to determine the sources of diversity. The collected findings indicated that the impact of PDT on enhancing the medical effectiveness of PWS was significant in different treatment sessions, different types of ages, different locations of PWS, and different types of PWS. Pain and edema occurred in most patients. Hyperpigmentation was present in 7.9–34.1% of the patients in 17 studies. Photosensitive dermatitis, hypopigmentation, blister, and scar were infrequently reported, with 0–5.8% incidences.ConclusionPhotodynamic therapy is recommended as a safe and effective treatment for PWS based on the current evidence. However, our findings are based on poor-quality evidence. Therefore, comparative investigations of a large scale and high quality are necessary to support this conclusion.
Clinical application of VATS combined with 3D-CTBA in anatomical basal segmentectomy
Authors: Zhang Lening , Wang Tuhui , Feng Yonggang , Chen Yizhao , Feng Chong , Qin Dongliang , Han Chunshan 
Published: February 2023

ObjectiveThis study aimed to summarize the clinical application experience of video-assisted thoracic surgery (VATS) combined with three-dimensional computed tomography-bronchography and angiography (3D-CTBA) in anatomical basal segmentectomy.MethodsClinical data of 42 patients who underwent bilateral lower sub-basal segmentectomy by VATS combined with 3D-CTBA in our hospital from January 2020 to June 2022 were retrospectively analyzed; the patients included 20 males and 22 females, with a median age of 48 (30–65) years. Combined with the preoperative enhanced CT and 3D-CTBA techniques to identify the altered bronchi, arteries, and veins during the operation, the anatomical resection of each basal segment of both lower lungs was completed through the fissure approach or inferior pulmonary vein approach.ResultsAll operations were successfully completed without conversion to thoracotomy or lobectomy. The median operation time was 125 (90–176) min, the median intraoperative blood loss was 15 (10–50) mL, the median postoperative thoracic drainage time was 3 (2–17) days, and the median postoperative hospital stay was 5 (3–20) days. The median number of resected lymph nodes was 6 (5–8). There was no in-hospital death. Postoperative pulmonary infection occurred in 1 case, lower extremity deep vein thrombosis (DVT) in 3 cases, pulmonary embolism in 1 case, and persistent air leakage in the chest in 5 cases, all of which were improved by conservative treatment. Two cases of pleural effusion after discharge were improved after ultrasound guided drainage. Postoperative pathology showed 31 cases of minimally invasive adenocarcinoma, 6 cases of adenocarcinoma in situ (AIS), 3 cases of severe atypical adenomatous hyperplasia (AAH), and 2 cases of other benign nodules. All cases were lymph node-negative.ConclusionVATS combined with 3D-CTBA is safe and feasible in anatomical basal segmentectomy; consequently, this approach should be promoted and applied in clinical work.
“Out of office”: Availability norms and feeling burned out during the COVID-19 pandemic: The mediating role of autonomy and telepressure
Authors: Hendrikx Karolien , Van Ruysseveldt Joris , Proost Karin , van der Lee Sandra 
Published: February 2023

IntroductionDigital innovations make it possible to work anywhere and anytime using any kind of device. Given these evolutions, availability norms are emerging at work. These norms specifically refer to the experienced beliefs or expectations from colleagues or superiors to be available for work-related communication after regular work hours. We rely on the Job-Demands Resources Model as we aim to investigate the relationship between these availability norms and burnout symptoms during the COVID-19 pandemic. We first of all study to what extent availability norms are associated with heightened burnout symptoms. Secondly, we study how both a personal demand, namely telepressure, and a job resource, namely autonomy, could offer distinct and relevant explanations for the role these availability norms play in experiencing burnout symptoms.MethodWe collected data through a survey study with 229 employees from various organizations in the second half of 2020.ResultsThe findings indicated that indeed availability norms are significantly associated with more burnout symptoms and that both heightened telepressure and reduced autonomy mediated this relationship.DiscussionThis study contributes to theory and practice as we offer insight into how availability norms at work could be detrimental for the occupational health of employees, which can be taken into account when setting up rules and regulations at work.
Sharing of cultural values and heritage through storytelling in the digital age
Authors: Zort Çağın , Karabacak Esra , Öznur Şevket , Dağlı Gökmen 
Published: February 2023

IntroductionSharing cultural values in this digital age for young generations who are digital natives is highly important and, in this respect, the aims of this study are to evaluate experts’ opinions on sharing cultural values in this digital age based on their experience, the roles of educators and families with respect to the sharing of cultural values through storytelling in the digital age, and also capture how cultural values can be explained with metaphors.MethodsA focus group interview was conducted with teachers and vice headmasters from public primary and secondary schools in the Northern part of Cyprus within the age range of 30-50 years that are considered to be experts based on their 10 years and above of teaching experience. Data were analyzed through line-by-line coding to create themes.ResultsFindings revealed that cultural values are eroding, and in sharing cultural values with storytelling in the digital age, the roles of educators and families are essential. Cultural values are the treasures and mirrors of society that should be preserved and transmitted to the younger generations and this can be accomplished through participation in digital platforms, and when such participatory cultural heritage projects are planned with a community-oriented background and human-centered computing concentration.DiscussionThis research sheds a light to indicate the importance of the storytelling approach for sharing cultural values and heritage. It is significant to address the merits of technology in transferring cultural values and heritage. In addition to this, this study is limited to one specific context that can be further explored as a cross-cultural analysis.
Sätze vom Bohman-Korovkin-Typ für lokalkonvexe Vektorverbände
Authors: Gonska Heiner 
Published: February 2023

Two Korovkin-type theorems inspired by the work of Scheffold are given concerning the approximation of a continuous lattice homomorphism \(P\) by a sequence of certain positive linear operators \(T_n\). The first result is used to prove a generalization of a proposition of Muller dealing with approximation in Banach function spaces.
Moral Principles of Women Poets in Purananuru
Authors: K Vennila 
Published: February 2023

Purananuru is a book that can be regarded as the historical treasury of Tamil literature. The culture, tradition, knowledge and commerce of the Tamils have been gathered together and become a literary ark. Women also excelled in the Sangam period because it was a time of emphasis on women's education. Women poets of the Sangam era have gained equal rights to men as a writer and have expressed their personality and ideas in a dignified way. These women did not hesitate to teach virtues to people through communal ideas. The purpose of this article is to bring out the moral principles of female poets in Purananuru from a social point of view. The personality of women poets in Purananuru, their hospitality, their modesty, their tendency to tell about the shortcomings of kings without hesitation, their courage, participating in the development of the country, and the heroic spirit of women poets are recorded in this article.
Virtues in Purananuru
Authors: N Kalyani 
Published: February 2023

This research is in the task of establishing the high quality of the human being, which needs to be corrected when the individual morality deviates from the normal state. The kings lived with fame by giving a proper explanation to fame and disrespect. Society puts forth certain moral principles that must be followed by human beings to lead a happiest life. Although there is a lot of internal literature that reflects the internal life, the external life, moral philosophies and high values with cultural symbols are recorded in the external literature of Purananuru. Many moral ideas followed in society are recorded and extolled in Purananuru. There are many moral ideals of the ancient Tamils in Purananuru which praise and protects the social virtues, which reflect life in the individual dimensions of social needs. This is explained here in a comparative manner through the song of Thirukkural.
Analisis Daya Dukung Tiang Pancang Pada Gedung Smpn 11 Tarakan Dengan Menggunakan Data Cpt Dan Kalendering
Authors: Mustakim Mustakim , Hasrullah Hasrullah 
Published: February 2023

ABSTRAK: Proyek konstruksi adalah pekerjaan mendirikan suatu bangunan dalam waktu yang telah ditentukan dan selesai tepat waktu atau bahkan lebih lepat dari waktu yang diperkirakan. Proyek kontruksi tentunya mempertimbangkan jenis tanah sebelum melakukan pembangunan pada lokasi tersebut dimana tanah memiliki peranan yang penting. Tujuan dari penelitian di Proyek Pembangunan Gedung Sekolah SMPN 11 Tarakan ini, untuk mengetahui jenis tanah dengan data sondir dan untuk mengetahui kapasitas daya dukung tiang pancang dengan menggunakan metode statis dan metode dinamis. Hasil perhitungan daya dukung tiang pancang kelompok dengan menggunakan metode statis pada titik sondir S-2 yang beban terbesarnya terdapat pada metode Mayerhoff sebesar 411,774 ton dan yang terkecil pada metode Shamertmann sebesar 111,330 ton. Daya dukung tiang pancang kelompok dengan menggunakan metode dinamis yang terbesarnya yaitu pada titik G-8-F metode AASHTO sebesar 1879,223 ton sedangkan yang terkecil pada titik G-8-C metode Janbu sebesar 409,014 ton. Angka keamanan (SF) pada metode statis pada titik sondir menghasilkan nilai SF terbesar pada titik sondir S-1 metode Mayerhoff sebesar 6,49 dan terkecil pada titik sondir S-5 metode Shamertmann sebesar 0,10. Pada metode dinamis menghasilkan nilai SF terbesar pada titik G-8-F metode AASHTO sebesar 6,63 dan yang terkecil pada titik G-8-C metode Janbu sebesar 1,44. Kata Kunci: Angka keamanan, klasifikasi tanah metode statis dan dinamis, penurunan tiang, pondasi tiang.
Studi Analisis Struktur Rangka Hanggar Pesawat Maf Kota Tarakan Berdasarkan Peraturan Terbaru (Sni 1727 2020 Dan Sni 1726 2019)
Authors: Apriliana Anna Celia , Utomo Edy 
Published: February 2023

ABSTRAK: Salah satu Hanggar Pesawat yang ada di Kota Tarakan adalah milik Yayasan MAF, yang dibangun sejak tahun 1980. Hanggar ini terletak di Jalan Mulawarman, Bandar Udara Juwata, Kota Tarakan. Infrastruktur hanggar digunakan sebagai tempat perawatan, tempat perbaikan, dan perlindungan pesawat dari cuaca luar. Konstruksi hanggar ini menggunakan struktur rangka atap dengan menerapkan material pipa baja galvanis. Saat ini telah diwajibkan perhitungan struktur menggunakan faktor gempa sesuai dengan SNI 1726 2019. Sehingga perlu untuk dilakukan identifikasi dari kekuatan struktur Hanggar Pesawat milik Yayasan MAF, dengan tujuan menilai kekuatan atau kestabilan struktur Hanggar Pesawat tersebut. Penelitian dilakukan dengan menggunakan model 2-Dimensi dan 3-Dimensi sesuai dengan kondisi eksisting Hanggar Pesawat tersebut. Berdasarkan analisis yang telah dilakukan baik pada pemodelan 2-Dimensi dan 3-Dimensi menunjukkan konstruksi Hanggar Pesawat mengalami ketidakstabilan struktur. Hal ini disebabkan oleh salah satu batang yaitu batang B130 tidak memenuhi syarat kelangsingan sebagai batang tekan atau batang tarik. Telah dilakukan analisis lebih jauh batang B130 tersebut ternyata tidak memberikan pengaruh signifikan terhadap Hanggar Pesawat, sehingga dapat dihilangkan sebagai salah satu elemen penyusun konstruksi Hanggar Pesawat tersebut. Kata Kunci: Hanggar Pesawat, Struktur Rangka Atap, Pipa Baja Galvanis, Batang Tarik, Batang Tekan