bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic and Health Promoting Potential of Terminalia chebula: An
Exploratory Literature Review
Authors: Chopra Manisha , Deswal Geeta , Chopra Bhawna , Kriplani Priyanka , Dass Rameshwar , Grewal Ajmer Singh , Dhingra Ashwani K. , Rathi Vaibhav 
Published: August 2023

:
The plant Terminalia chebula has been used traditionally in many regions of the world
for its therapeutic properties, especially in India. Its therapeutic and health-promoting potential has
been recognized for centuries, and modern research continues to unveil its numerous benefits. One
of the most significant applications of this plant is its antimicrobial and antioxidant potential. The
plant contains high levels of phenolic compounds and flavonoids, which scavenge harmful free
radicals in the body, reducing oxidative stress and cellular damage. This antioxidant action contributes
to its anti-inflammatory effects, making it beneficial for a wide range of conditions, including
arthritis, cardiovascular diseases, and neurodegenerative disorders. Furthermore, Terminalia
chebula exhibits antimicrobial activity against various bacteria and fungi, including those responsible
for common infections. It has been used to treat respiratory infections, urinary tract infections,
and skin ailments. Its broad-spectrum antimicrobial effects make it a valuable natural remedy for
combating microbial pathogens. Moreover, Terminalia chebula shows potential in managing diabetes
and promoting cardiovascular health. Studies have indicated its ability to regulate blood sugar
levels, improve insulin sensitivity, and reduce lipid abnormalities. These properties make it a
promising adjunct therapy for individuals with diabetes or at risk of heart disease. In conclusion,
Terminalia chebula possesses remarkable therapeutic and health-promoting potential. Its antioxidant,
anti-inflammatory, antimicrobial, and digestive benefits make it a valuable natural remedy for
various ailments. While research on Terminalia chebula is ongoing, its long-standing use in traditional
medicine and emerging scientific evidence solidify its status as a potent medicinal plant with
diverse applications in promoting overall well-being.
Nano-based Herbal Medicine: A New Candidate for Prostate Cancer
Treatment?
Authors: Pouryousefi-koodehi Tayebe , Kahrizi Mohammad Saeed , Roghani-Shahraki Hossein , Rezaei-Tazangi Fatemeh , Arefnezhad Reza , Motedayyen Hossein 
Published: August 2023

Background:
Prostate cancer (PCa) is known as the fifth reason for cancer-related
deaths and involves a considerable population of men globally. In PCa, pluriform neoplasm with
different cancer patterns is formed. Metastases have a substantial role in disease mortality, and
lung, liver, and bone are among the common organs for metastasis. In spite of multiple attempts by
researchers, it has not been recommended a safe and suitable approach against PCa so far.

Results:
Fortunately, herbal remedies have opened a novel window in order to treat several cancers,
such as PCa; however, there are some barriers regarding this curative method, like low bioavailability
and absorption and low water solubility. On the contrary, some nano-based formulations
have revealed a potential ability to overcome these limitations, and it seems that the co-use of
herbal products and nanoformulations provides a good opportunity for treating PCa.

Conclusion:
In this study, we argued about the therapeutic aspects of some nanoformulations of
popular herbal products, such as curcumin, quercetin, and resveratrol, against PCa.
Assessment of Power Quality Enhancement in a Grid-tied PV Network via
ANN-based UPQC
Authors: Kumar Ch. Phani , Elanchezhian E.B. , Subramani Pragaspathy , Subramanian S. 
Published: August 2023

Background:
Microgrid is the recent decade terminology that surpasses the long-run issues
associated with the public and utility grids. Among the renewable energy sources, solar PV
units have gained greater importance owing to their huge potential availability and laidback operating
characteristics on technological grounds. Conversely, it offers pollution-free electricity and perhaps
the dependability is volatile in most situations. The literature study accumulates the foresaid
setback and presents the fluctuation-less and controlled standard quality of power outputs.

Objective:
The aim of this particular research is to propose an assessment of Power Quality enhancement
in a Grid-tied photovoltaic (PV) network via ANN-based UPQC. The novel idea behind
this proposed approach is the UPQC component which deliberately regulates and controls the power
system to achieve higher levels of power quality, ultimately meeting the recent IEEE standards.

Method:
This particular research enhances the performances of UPQC employed in the microgrid
unit by replacing the traditional PI controller with a multi-layered feed-forward-type ANN controller
for the current regulation of the series active filter. Additionally, a training algorithm for the
ANN controller is built, trained and simulated via MATLAB/Simulink platform. The ANN-based
UPQC is proposed to alleviate the power quality challenges like sag and swell in voltage, harmonic
distortion, the time required for voltage compensation, and power factor. Therefore, UPQC is
equipped to enrich the standard of power transfer at the point of common coupling inside the power
frameworks, respectively.

Result:
Finally, the simulation results are presented to validate the operation of the grid-tied PV
network via an ANN-based UPQC system. To show the enriched performance of the proposed topology,
a comparative analysis is made with PI controller-based UPQC, and outcomes infer to be in
agreement with the theoretical discussions. Also, the ANN-based proposed approach reduces the
restoration time and THD as well under both sag and swell conditions, respectively.

Conclusion:
In this articulated work, a PV power system network with a DC-DC converter and
three-phase inverter is employed for grid integration. The peak power extraction is ensured via a
DC-DC converter with an incremental conductance algorithm. Both UPQCs are analysed and experimented
via MATLAB/Simulink platform with inconstant nonlinear loads to investigate the indices
mentioned above and corroborate the same within the operating regions.
Titanium Complexes: Cytotoxic and Antiproliferative Effects on HeLa, C6,
and CHO Cell Lines
Authors: Kumar Nitesh , Kaushal Raj , Chaudhary Ashun , Arora Saroj , Awasthi Pamita 
Published: August 2023

:
The antiproliferative studies of Titanium(II) complexes of composition TiCl2 (L)2 [L = 2,2'-bipyridine (bipy), 4,4'-dimethyl-2,2'-bipyridine (bpMe), 4,4'-dimethoxy-2,2'-bipyridine (bpoMe), 6,6'-dimethyl-2,2'-bipyridine (dpMe), adamantylamine (ada)] were done against three different HeLa (cervical), C6 (glioma) and CHO (Chinese hamster ovarian) cell lines. It has been observed that the complex with 6,6'-dimethyl-2,2'-bipyridine (dpme) ligand was more potent against HeLa cell lines with an IC50 value of 9.10 μM but less effective than the known anticancer drug Camptothecin (IC50= 6.2 μM). Furthermore, cell cycle analysis was accomplished on CHO cell lines to discover the cell death mechanism. It has been observed that all complexes induce cell death through an increase in hypo-diploid cells (Sub-G1 population), which indicates apoptosis in a dose-dependent manner.

Objective:
Cytotoxic studies of synthesized titanium complexes on three different cell lines; MTT assay; cell cycle analysis.

Methods::
MTT assay: The cytotoxic activity of the synthesized complexes against the HeLa, C6, and CHO cell lines was determined using the colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. This assay was carried out in triplicate on 96 plates, with a well-defined procedure and minor modifications.

Result::
Cell cycle analysis: Cells were plated at 1×106 cells/dish in 24-well plates and then grown either in the presence or absence of the complex at three different concentrations,i.e.below and above IC50 and at IC50 values. After 24 h of treatment, the cells were harvested from the dishes by collecting trypsinized cells together with floating cells in the medium.

Conclusion::
In the present paper, we have reported the cytotoxic studies of previously reported titanium complexes against HeLa, C6, and CHO cell lines. The results have shown that titanium complex (D1) having 6,6'-dimethyl-2,2'-bipyridine ligand was more effective against the HeLa cell line. The morphological changes in CHO cells indicate characteristic features similar to apoptosis, and cell cycle analysis indicates an increase in hypo-diploid cells.
Characterization of Ceria Powders as a Continuous Search for New Rare-earth Based Materials for Radiation Dosimetry
Authors: dos Santos Silas Cardoso , Júnior Orlando Rodrigues , Campos Letícia Lucente 
Published: August 2023

Background:
Ceria (CeO2) belongs to rare-earth series and due to its profitable
properties, presents a wide commercial use such as catalysis, energy, biological,
biomedical, and pharmaceutical. The features of the starting materials in the form of
free powders influence notably the processing, formation, as well as characteristics of
the final structures\bodies obtained by colloidal processing. This study aims to characterize
CeO2 powders. The results obtained are worthwhile data to advance toward new
rare-earth based materials for radiation dosimetry.

Methods:
CeO2 powders were evaluated by the following techniques: PCS, SEM, XRD,
FT-IR, EPR, IPC, and pycnometric density (ρ). The stability of particles in aqueous solvent
was evaluated by zeta potential (ζ) determination.

Results:
CeO2 powders exhibited cubic C-type form, Fm-3m space group, a mean particle
size (d50) of 19.3nm, and a pycnometric density (ρ) of 7.01g.cm-3. Based on the results
of zeta potential determination, CeO2 powders exhibited high stability at pH 6.4 with ζ-
value of |34.0|mV.

Conclusion:
The evaluation of CeO2 powders was reported. The results presented and
discussed in this study contribute to advance in the search of new rare-earth based materials
for radiation dosimetry.
Effect of Saccharolactone on CYP-mediated Metabolism of Xenobiotics
Authors: Behera Dayanidhi , Jain Pankaj , Kurawattimath Vishwanath , Gowda Nagaraj 
Published: August 2023

Background:
Saccharolactone is used as a β-glucuronidase inhibitor in in vitro micro-somal and recombinant uridine diphosphoglucuronosyl transferases (rUGTs) incubations to en-hance glucuronide pathway and, thereby, formation of glucuronide metabolites. We investigated its effect on CYP mediated metabolism of drugs (compound-174, phenacetin and quinidine) using human liver microsomes (HLM) supplemented with Phase-1 and Phase-2 co-factors.

Methods:
Compounds were incubated in HLM supplemented with co-factors to assess Phase-1 (NADPH) and Phase-2 (NADPH, alamethicin, saccharolactone and UDPGA) metabolism. CYP phenotype assay for compound-174 was conducted in HLM (± 1-ABT) and human recombinant CYP isoforms. CYP inhibition profile of saccharolactone was also generated in HLM.

Results:
The metabolism of compound-174, phenacetin and quinidine in HLM significantly de-creased in reactions containing additional components like alamethicin, saccharolactone and UD-PGA and indicated that the addition of saccharolactone inhibited the metabolism. Phenacetin and quinidine are known substrates of CYP1A2 and CYP3A4 isoforms. The metabolism of com-pound-174 was significantly inhibited in the presence of 1-ABT in HLM, and CYP3A4 and CYP2C8 isoforms were found to be the predominant isoforms responsible for its metabolism. Fur-ther evaluation of CYP inhibition in HLM indicated saccharolactone to be a strong inhibitor of CYP1A2, 2D6, 3A4 and 2C8 isoforms with IC50 values of less than 4 mM.

Conclusion:
The findings indicated that saccharolactone being a strong inhibitor of CYP1A2, 2D6, 3A4 and 2C8 isoforms (IC50 < 4 mM), resulted in significant inhibition of the metabolism of compound-174, phenacetin and quinidine in HLM and caution should be exercised in using it with proper titration of the concentrations.
Luz síncrotron promovendo o giro decolonial
Authors: Acioly Vitor , Morais Rodrigo , Santos Antonio 
Published: August 2023

Este artigo é um recorte de uma pesquisa de doutorado de caráter qualitativo, visando, inicialmente, investigar como os cursos de formação continuada contribuem para que docentes da área de exatas transformem suas práticas de ensino, por meio da valorização dos seus saberes e das possibilidades de reflexão e aprendizagem. Pela análise do discurso dos sujeitos participantes de um curso de formação continuada de professores, percebeu-se que, no imaginário deles, existia um local exclusivo de produção de conhecimento significativo e que esse tipo de percepção colaborava de maneira efetiva para invisibilizar contribuições científicas brasileiras. Os dados empíricos foram produzidos pela observação participante durante a Escola Sirius para Professores do Ensino Médio (ESPEM) oferecida presencialmente nos anos de 2019 e 2020, a partir de narrativas dos sujeitos participantes. Os resultados indicam uma subalternização epistemológica por meio de discursos que exaltam a produção científica de países europeus e que apagam a produção científica brasileira. As análises também indicam o papel da ESPEM na promoção de uma virada decolonial.
EVALUASI BOBOT KERING TAJUK DAN BOBOT DOMPOLAN (HEAD) BEBERAPA GENOTIPE SORGUM (Sorghum bicolor [L.] Moench) MELALUI SIDIK LINTAS (PATH ANALYSIS)
Authors: Hadi Muhammad Syamsoel , Ratu Aisyan Nur Anana , Setiawan Kukuh , Kamal Muhammad 
Published: August 2023

Penelitian ini bertujuan untuk mengevaluasi bobot kering tajuk dan bobot dompolan (head), menghitung korelasi antara komponen pertumbuhan dan hasil berbagai genotipe sorgum, dan menentukan pengaruh langsung dan tidak langsung berbagai komponen pertumbuhan dan hasil terhadap bobot dompolan yang dihitung menggunakan sidik lintas pada berbagai genotipe sorgum. Penelitian dilakukan di Desa Sukanegara, Kecamatan Tanjung Bintang, Kabupaten Lampung Selatan, Provinsi Lampung, pada April sampai November 2019. Tujuh genotipe sorgum (Super-1, Mandau, P/I 150-21-A CYMMIT, P/F 5-193-C, P/F 10-90-A, UPCA, dan Talaga Bodas) disusun dalam Rancangan Acak Kelompok Lengkap (RAKL) dengan tiga ulangan. Hasil penelitian menunjukkan terdapat variasi bobot kering tajuk dan bobot dompolan antargenotipe. Genotipe Mandau dan P/F 10-90 A menghasilkan bobot kering tajuk (66,93 g dan 56,46 g) dan bobot dompolan (52,68 g dan 56,81 g) lebih tinggi dibanding genotipe lain. Terdapat korelasi positif antara bobot kering tajuk dengan bobot dompolan (r=0,76**), serta bobot dompolan dengan bobot biji (r=0,90**). Bobot kering tajuk memiliki nilai pengaruh langsung terhadap bobot dompolan sebesar 0,6037. Selain itu, bobot biji memiliki pengaruh langsung terhadap bobot dompolan sebesar 0,7373.
HAMA-HAMA TANAMAN JAGUNG DAN KERAGAMAN ARTROPODA PADA PERTANAMAN JAGUNG DI KABUPATEN PESAWARAN DAN LAMPUNG SELATAN, PROVINSI LAMPUNG
Authors: Purnomo Purnomo , Ananda Ellen Aprilia , Fajar Ahmad Al , Wibowo Lestari , Lestari Puji , Swibawa I Gede 
Published: August 2023

Penelitian ini bertujuan untuk mengetahui berbagai jenis hama utama yang ditemukan selama masa pertumbuhan tanaman jagung, serta keragaman artropoda yang ada pada ekosistem pertanaman jagung di Kabupaten Lampung Selatan dan Pesawaran, Provinsi Lampung. Pengamatan dilakukan di empat lokasi: dua lokasi di Lampung Selatan dan dua lokasi di Pesawaran. Pada keempat lokasi tersebut cara budidaya tanaman jagungnya sama, yang berbeda adalah varietas jagung yang ditanam. Hasil pengamatan menunjukkan bahwa hama-hama utama yang menyerang tanaman jagung pada fase vegetatif dan generatif adalah Peregrinus maidis (Hemiptera: Delphacidae), Spodoptera frugiperda (Lepidoptera:Noctuidae), Ostrinia furnacalis (Lepidoptera:Crambidae), dan Helicoverpa armigera (Lepidoptera:Noctuidae). Populasi fitofag yang juga cukup tinggi adalah Leptocorisa oratorius (Hemiptera: Coreidae), meskipun serangga ini sangat jarang diklaim sebagai hama penting tanaman jagung. Di antara 5 spesies serangga fiotofag tersebut, populasi tertinggi ditempati oleh hama P. maidis yang ditemukan pada semua lahan pengamatan. Perbedaan varietas berpengaruh terhadap populasi hama-hama pada pertanaman jagung. Hasil penelitian juga menunjukkan bahwa di Lampung Selatan: Way Layap (BISI-18) ditemukan 10 ordo dan 49 famili, lokasi Suka Bandung (SUMO) ditemukan 13 ordo dan 52 famili. Adapun di Pesawaran: Sri Mulyo (Pioneer-27) ditemukan 12 ordo dan 51 famili, dan di lokasi Solehudin (BISI-321) ditemukan 12 ordo dan 49 famili. Artropoda yang ditemukan berperan sebagai hama, predator, parasitoid, polinator, dan dekomposer. Indeks keragaman artropoda tergolong dalam kategori sedang dengan nilai tertinggi di lokasi Suka Bandung (2,34). Indeks dominasi tertinggi di lokasi Sri Mulyo dengan nilai 0,43. Indeks kemerataan tertinggi di lokasi Suka Bandung dan Way Layap dengan nilai 0,59.
EKSPLORASI MIKROORGANISME PROKARIOT ASAL BONGGOL PISANG UNTUK MENGENDALIKAN PENYAKIT LAYU FUSARIUM PADA TANAMAN PISANG SECARA IN VITRO
Authors: Elvara Ramasta Nesya , Nurdin Muhammad , Ivayani Ivayani , Dirmawati Suskandini Ratih 
Published: August 2023

Fusarium oxysporum f. sp cubense (E.F.Smith) Snyder dan Hansen (Foc) merupakan patogen yang menyebabkan penyakit layu fusarium pada tanaman pisang. Saat ini usaha pengendalian masih menggunakan pengendalian kimiawi, namun pengendalian kimiawi yang berlebihan dapat menimbulkan kerugian pada manusia dan lingkungan. Salah satu alternatif yaitu menggunakan agensi hayati yang berasal dari fermentasi bahan-bahan alami yang mengandung mikroorganisme lokal (MOL). Salah satu limbah pertanian yang dapat digunakan dalam membuat larutan MOL adalah bonggol pisang. Kandungan gizi dalam bonggol pisang dapat digunakan mikroorganisme lokal baik untuk berkembang. Penelitian ini bertujuan untuk mengetahui: (1) mengetahui beberapa karakteristik mikroorganisme prokariot yang terkandung dalam larutan MOL asal bonggol pisang, (2) mengetahui kemampuan masing-masing mikroorganisme prokariot yang terkandung dalam larutan MOL asal bonggol pisang dalam menekan pertumbuhan Foc secara in vitro, (3) mengetahui kemampuan masing-masing mikroorganisme prokariot yang terkandung dalam larutan MOL asal bonggol pisang dalam memacu pertumbuhan mentimun. Penelitian ini dilakukan di Laboratorium Hama dan Penyakit Tumbuhan Universitas Lampung untuk pengujian secara in vitro dan PT Great Giant Food Lampung Timur untuk pengambilan bonggol pisang dan sumber inokulum Foc. Metode penelitian ini terdiri dari 2 tahap yaitu eksplorasi mikroorganisme lokal dan pengujian masing-masing bakteri hasil eksplorasi mikroorganisme lokal terhadap patogen Foc. Hasil penelitian menunjukkan bahwa (1) hasil uji karakteristik didapatkan bahwa isolat BP1 dan isolat BP2 bersifat gram positif, sedangkan isolat BP3 bersifat gram negatif dan ketiga isolat tersebut tidak softrot dan tidak hipersensitif serta bersifat hipovirulen, (2) isolat BP1, BP2, dan BP3 mampu menghambat pertumbuhan patogen Foc secara in vitro, dan (3) isolat BP1, BP2, dan BP3 mampu memacu pertumbuhan panjang akar tanaman dan jumlah rambut akar pada kecambah mentimun.
RESPON TANAMAN BAWANG MERAH (Allium ascalonicum L.) KULTIVAR BIMA BREBES TERHADAP BERBAGAI JENIS BIOCHAR
Authors: Trisnaningsih Umi , Pujiana Pujiana , Saleh Ismail 
Published: August 2023

Biochar adalah hasil pirolisis dari bahan organik limbah pertanian yang digunakan sebagai ameliorant tanah. Pada penelitian ini diuji biochar dari berbagai bahan yang berbeda, untuk mengetahui pengaruhnya terhadap pertumbuhan dan hasil bawang merah kultivar Bima Brebes. Percobaan dilaksanakan di Desa Palir, Kabupaten Cirebon. Metode yang digunakan dalam penelitian ini adalah metode eksperimen, rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok. Perlakuan berbagai jenis biochar yang terdiri dari 6 taraf perlakuan meliputi kontrol, biochar tempurung kelapa, biochar ampas tebu, biochar brangkasan jagung, biochar limbah bambu dan biochar jerami padi. Semua perlakuan diulang 4 kali. Variabel yang diamati meliputi tinggi tanaman, jumlah daun, jumlah anakan, volume akar, bobot umbi basah per rumpun dan per petak, serta bobot umbi kering per rumpun dan per petak. Hasil penelitian menunjukan bahwa berbagai jenis biochar berpengaruh nyata terhadap pertumbuhan dan hasil bawang merah. Bahan baku biochar yang terbaik pengaruhnya terhadap pertumbuhan dan hasil tanaman bawang merah adalah brangkasan jagung.
SURVEI KEPADATAN POPULASI HAMA DAN AGENSIA HAYATI PADA TANAMAN PADI SAWAH DI DESA TIRTALAGA KABUPATEN MESUJI, PROVINSI LAMPUNG
Authors: Wibowo Lestari , Safitri Khofifah Nur Indah , Nurmauli Niar , Hariri Agus M 
Published: August 2023

Penelitian dilaksanakan bulan November 2021 sampai Januari 2022 bertempat di Desa Tirtalaga Kabupaten Mesuji, Provinsi Lampung yang bertujuan untuk mengetahui kepadatan populasi hama penting dan agensia hayati hama pada tanaman padi sawah. Metode penelitian dilakukan dengan cara survei (pengamatan langsung di lapang). Pengamatan ini dilakukan pada persawahan milik Kelompok Tani Makmur, Kelompok Tani Suka Maju, Kelompok Tani Sumber Rezeki, dan Kelompok Tani Suka Jadi. Pengamatan dilakukan sebanyak 12 kali sejak tanaman padi berumur 1 MST-12 MST. Jenis hama yang ditemukan di tanaman padi sawah adalah hama putih palsu (Cnapalocrosis medinalis), wereng batang coklat (Nilaparvata lugens), penggerek batang padi putih (Scirpophaga innotata), wereng hijau (Nephotettix viresecens), dan walang sangit (Leptocorisa oratorius). Kepadatan populasi C. medinalis pada minggu ke-1 dan 2 di semua hamparan berada di atas ambang ekonomi, sedangkan pada minggu berikutnya populasi menurun hingga di bawah ambang ekonomi. Kepadatan populasi N. lugens, S. innotata, N. virescens, dan L. oratorius pada semua hamparan berada di bawah ambang ekonomi. Agensia hayati yang ditemukan antara lain Coccinellidae, Scarabaeidae, Dytiscidae, Andrallus spinidens, Tetragnathidae, Araneidae, Lycosidae, Pipunculidae, Coenagrionidae, Gomphidae, Mymaridae, Eurytomidae, Encyrtidae, Ichneumonidae, Formicidae, Dryinidae, Braconidae, Trichogrammatidae, dan Forficulidae
PENGARUH EKSTRAK RIMPANG TEMU IRENG, DAUN KELOR DAN STREPTOMYCES SP. TERHADAP PERKECAMBAHAN SPORA PERONOSCLEROSPORA SP. DAN DAN KETERJADIAN PENYAKIT BULAI JAGUNG
Authors: Aslinda Erni , Aeny Titik Nur , Prasetyo Joko , Sudiono Sudiono , Dirmawati Suskandini Ratih 
Published: August 2023

Penggunaan fungisida nabati dan agen pengendali hayati merupakan satu alternatif dalam pengendalian penyakit bulai pada tanaman jagung. Ekstrak rimpang temu ireng, daun kelor dan bakteri Streptomyces sp. dilaporkan memiliki kandungan senyawa yang perpotensi sebagai antijamur. Penelitian ini bertujuan untuk (1) mengetahui pengaruh ekstrak rimpang temu ireng dan daun kelor terhadap perkecambahan spora Peronosclerospora sp., intensitas penyakit bulai dan pertumbuhan tanaman jagung, dan (2) mengetahui pengaruh interaksi antara ekstrak tanaman dengan Streptomyces sp. terhadap intensitas penyakit bulai dan pertumbuhan tanaman jagung. Penelitian ini menggunakan rancangan acak kelompok yang disusun dalam faktorial. Faktor pertama merupakan jenis ekstrak tanaman (tanpa ekstrak, ektrak temu ireng, ekstrak daun kelor) dan faktor kedua adalah jenis isolat Srteptomyces sp. (tanpa Streptomyces, isolat I1, dan isolat i18) sehingga terdapat 9 perlakuan. Masing-masing perlakuan diulang sebanyak 4 kali sehingga diperoleh 36 satuan percobaan. Hasil penelitian menunjukkan bahwa ekstrak rimpang temu ireng dan daun kelor berpengaruh nyata dalam menghambat perkecambahan spora Peronosclerospora sp., memperpanjang masa inkubasi, menekan intensitas penyakit bulai dan meningkatkan pertumbuhan tanaman jagung. Interaksi antara ekstrak tanaman dan isolat Streptomyces sp. hanya perpengaruh nyata dalam memperpanjang masa inkubasi penyakit bulai tanaman jagung. Ekstrak tanaman dapat menekan intensitas penyakit bulai dan pertumbuhan tanaman jagung sedangkan Streptomyces tidak berpengaruh.