bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of pathogenic bacteria isolated from diseased stinging catfish, Shing (Heteropneustes fossilis) cultured in greater Mymensingh, Bangladesh
Authors: Monir Md Shirajum , Borty Shuvho Chakra , Bagum Nazneen , Rahman Md Khalilur , Islam Md  Alimul , Mahmud Yahia 
Published: July 2023

Stinging catfish, Shing (Heteropneustes fossilis) is been cultured in Bangladesh which is one of the most popular and highly valuable fish species. A total of 120 diseased H. fossilis were collected from twenty five fish farms in greater Mymensingh region, Bangladesh between November 2013 to February 2014. Remarkable clinical symptoms of the affected fishes were loss of equilibrium and, erosions at the bases of fins and tail, hemorrhages and skin lesions on body surface, profuse mucous secretion and congestion along with enlargement of most of the internal organs. Three different kinds of selective media were used for the isolation of total population of bacteria from the affected fishes. A number of biochemical tests were performed for the identification of the isolated bacteria. Commercially available panel of antibiotics were used for the determination of sensitivity of the isolated bacteria. A total of 85 bacterial strains were isolated and the isolated were Aeromonas hydrophila, A. salmonicida, A. sobria, Pseudomonas angulliseptica, P. fluorescens and Vibrio anguillarum. Aeromonas spp. appeared to be the main pathogen in the diseased fishes. Among the isolated spp of bacteria distribution of Aeromonas species was as follows: A. hydrophila 34 (40.00%), A. salmonicida 14 (16.47%), A. sobria 8 (9.41%) as well as 5 (5.88%) unidentified Aeromons strains. The other isolated of Pseudomonas anguliseptica, P. fluorescens, Vibrio anguillarum and Vibrio spp were distributed as 12 (14.11%), 4 (4.70%), 3 (3.52%) and 5 (5.88%), respectively in infected H. fossilis. However, results of antibiotic sensitivity test revealed that all the bacterial isolates of H. fossilis were found more or less resistant to all most all the antibiotics with the exception of ciprofloxacin and levofloxacinn which were found highly sensitivity against all the strains of Aeromonass pp. and other species of bacteria.
Asian Australas. J. Biosci. Biotechnol. 2016, 1 (1), 116-124
The productive and reproductive performance of indigenous buffaloes at Kawkhali Upazilla, Pirojpur in Bangladesh
Authors: Rahman Md Hafizur , Datta Suvanker , Manik Md Ahsan Ulla , Kabir Md Humayun , Talukder Milton , Matin Md Abdul 
Published: July 2023

The productive and reproductive performance of indigenous buffaloes at Kawkhali Upazilla under Pirojpur district was studied. Fifty seven (57) buffalo owners were interviewed by written interviewed paper from Kawkhali Upazilla under Pirojpur district in 2010. Out of 57 families 30 containing 45 milch cows, 34 dry cows, 42 heifer calves, 23 bull calves and 17 bull which were counted for calculation. The study demonstrated that the distribution of buffalo populations were scattered and the average buffalo populations were 5.37 per house-holds, age at puberty 45.03 ± 6.97 months, lactation length 242.60±41.46 days, milk yield 2.35±0.703 liters/day, gestation period 317.47±6.57 days, body weight 23.77±5.20 kg/calf, age at first calving 55.33±7.20 months, calving interval 650.93±79.57 days and average post partum heat period was 235.90±52.24 days. These data will be helpful for future research and also give a guideline for buffalo development in Bangladesh.
Asian Australas. J. Biosci. Biotechnol. 2016, 1 (2), 161-165
Comparative in-vitro dissolution study and infrared characterization of binary solid dispersion of diclofenac sodium
Authors: Akhter Sharmin , Barua Jewel , Salahuddin Md , Dey Rupantar , Das Joysree , Jenny Anowara 
Published: July 2023

Diclofenac sodium, a non-steroidal antiinflammatory agent was selected as a model drug for the study, which is BCS class II drug (low soluble and high permeable). Poor water solubility of any drug is characterized by low dissolution rate and consequently reduced bioavailability. Numerous methods have been followed in literature to improve the dissolution rate of poorly water soluble drugs. The objective of the present study was to improve the water solubility and the dissolution rate of poorly water soluble diclofenac sodium by solid dispersion (SD) technique. Binary SDs of diclofenac sodium were prepared by physical mixing as well as solvent evaporation technique using a highly water soluble polymer Eudragit E-100 in different drug-to-polymer weight ratios (1:1 to 1:5). The effect of the carrier Eudragit E-100 on the solubility and in-vitro dissolution behavior were investigated spectrophotometrically at 273 nm. It was found that only 11.43% was released within 60 minutes from active diclofenac sodium on the other hand the release of diclofenac sodium from the binary SD formulation of solvent evaporation containing Eudragit E-100 in 1:5 ratio (code: S9) showed the best result which was 98.57% within the same period of time. Evaluation of the properties of the prepared SDs formulations were performed by using Fourier Transform Infra Red (FTIR) spectroscopy. The FTIR spectroscopic data showed that though the stability of drug was enhanced due to Eudragit E-100, but there was absence of considerable drug-polymer interactions. So solid dispersion may be an effective technique to enhance dissolution rate of diclofenac sodium.
Asian Australas. J. Biosci. Biotechnol. 2016, 1 (2), 353-361
IMPLEMENTASI PERWALI SURABAYA NO. 5 TAHUN 2013 TENTANG PEDOMAN PEMANFAATAN TEKNOLOGI INFORMASI DAN KOMUNIKASI
Authors: Rahmadanik Dida , Mardiyanti Nurul Ika , Murti Indah 
Published: July 2023

Based on the Surabaya Mayor Regulation Number 5 of 2013 concerning Guidelines for the Use of Information and Communication Technology in the Implementation of Regional Government, that in each agency making innovations which utilizes information and communication technology in providing services based on convenience for users; without barriers between one institution and another; transparent and the availability of public information; fairness; accountable; and service standardization. But in reality many teachers have difficulty in using it. This study aims to describe the application of the SIAGUS application at SMPN 52 Surabaya along with its supporting and inhibiting factors. This type of research is using descriptive qualitative. The focus of his research uses the theory of indicators of successful implementation of e-government based on the results of a study from the Harvard JFK School of Government namely Support, Capacity, and Value. The results of this study indicate that the application of the SIAGUS application at SMPN 52 Surabaya is quite good when viewed from the indicators of Support, Capacity, and Value but there are still teachers who do not understand how to use the SIAGUS application so that in-depth assistance is needed by forming small groups and additional appointments. operators to be included in the group. In addition, server errors were also encountered so that there was a need for repairs or additional capacity on the central server at the Surabaya City Education Office.AbstrakBerdasarkan Peraturan Walikota Surabaya Nomor 5 Tahun 2013 tentang Pedoman Pemanfaatan Teknologi Informasi dan Komunikasi dalam Penyelenggaraan Pemerintahan Daerah bahwa dalam tiap instansi membuat inovasi yang memanfaatkan teknologi informasi dan komunikasi dalam memberikan pelayanan yang berasaskan pada kemudahan bagi pemgguna; tanpa jarak antara satu instansi dengan instansi lain. Namun pada kenyataannya banyak guru yang mengalami kesulitan dalam menggunakannya. Penelitian ini bertujuan untuk mendeskripsikan mengenai penerapan aplikasi SIAGUS di SMPN 52 Surabaya berserta dengan faktor pendukung dan penghambatnya. Jenis penelitian ini menggunakan deskriptif kualitatif. Fokus penelitiannya menggunakan teori indikator keberhasilan penerapan e-government berdasarkan hasil kajian dari Harvard JFK School of Government yaitu Support, Capacity, dan Value. Hasil penelitian ini menunjukkan bahwa penerapan aplikasi SIAGUS di SMPN 52 Surabaya cukup baik apabila dilihat dari indikator Support, Capacity, dan Value namun juga masih ditemukan guru yang kurang paham dalam menggunakan aplikasi SIAGUS sehingga perlu dilakukan pendampingan secara mendalam dengan cara membentuk kelompok kecil dan penunjukan tambahan operator untuk dimasukkan ke dalam kelompok tersebut. Selain itu juga ditemui server eror sehingga perlu adanya perbaikan atau penambahan kapasitas pada server pusat di Dinas Pendidikan Kota Surabaya.
Karakteristik Yoghurt Probiotik dari Filtrat Biji dan Daging Buah Labu Madu dengan Lama Fermentasi yang Berbeda
Authors: Nasarani Eunike Elisa Beth , Winarti Sri 
Published: July 2023

Biji dan daging labu madu dapat dimanfaatkan sebagai yoghurt. Penelitian ini bertujuan untuk mengetahui pengaruh proporsi filtrat biji dan filtrat daging labu madu serta lama fermentasi terhadap karakteristik fisik, kimia, mikrobiologi dan organoleptik yoghurt probiotik serta menentukan perlakuan terbaik. Penelitian ini menggunakan rancangan acak lengkap (RAL) pola faktorial dengan dua faktor yaitu proporsi filtrat biji dan daging buah labu madu ((90:10), (80:20), (70:30)) v/v dan lama fermentasi (20 jam, 22 jam, 24 jam) dengan tiga kali ulangan. Data dianalisis menggunakan ANOVA 5% dan uji lanjut DMRT 5%. Hasil penelitian menunjukkan, bahwa perlakuan terbaik filtrat biji: filtrat daging buah (80:20) dengan lama fermentasi 22 jam menghasilkan yoghurt probiotik dengan karakteristik: total BAL 9,24 log CFU/ml; total asam tertitrasi (TAT) 1,49%; pH 3,89 ; padatan terlarut 21,953°Brix; viskositas 1011 m.Pas dan N-amino 2,513%;, sedangkan uji organoleptik (hedonik) menunjukkan rata-rata skor kesukaan warna 5,13 (agak suka), aroma 3,60 (agak tidak suka), rasa 5,73 (agak suka), dan tekstur 4,87 (biasa) total bakteri probiotik Bifidobacterium bifidum 7,39 log CFU/ml, betakaroten 2,64 µg/ g, serat pangan 5,725 %.
Analisis Dinamik Model Penyebaran Rumor Ignorances-Discussant-Spreader-Remover (IDSR) pada Jejaring Sosial
Authors: Darajat Pangestuti Prima , Robby Rizka Rizqi , Rasikhun Hady , Ikawati Deasy Sandhya Elya 
Published: July 2023

Penyebaran rumor memberikan banyak dampak negatif pada kehidupan sosial masyarakat. Karakteristik penyebaran rumor perlu dipelajari untuk mendapatkan informasi ilmiah sekaligus menentukan strategi pengendalian yang tepat. Pada penelitian ini dikontruksi model penyebaran rumor Ignorances-Discussant-Spreader-Remover (IDSR) dengan memperhatikan faktor pemberian pernyataan balasan. Pada model dilakukan analisis dinamik dengan menentukan titik kesetimbangan, eksistensi, serta kestabilan lokal titik kesetimbangan tersebut. Diperoleh bahwa, titik kesetimbangan bebas rumor eksis dengan kriteria kestabilan tertentu. Sementara itu dua titik kesetimbangan lain memiliki syarat eksistensi dan ditentukan syarat kestabilannya menggunakan kriteria kestabilan Routh-Hurwitz. Simulasi numerik dilakukan menggunakan metode rungge-kutta orde 4 dan software MATLAB untuk menggambarkan karakteristik masing-masing titik kesetimbangan tersebut serta membuktikan analisa teoritis yang dilakukan.
Finite element analysis of biomechanical effects of mineralized collagen modified bone cement on adjacent vertebral body after vertebroplasty
Authors: Yang Cunheng , Wang Fumin , Huang Xingxing , Zhang Hao , Zhang Meng , Gao Junxiao , Shi Shengbo , Wang Fuyang , Yang Fangjun , Yu Xiaobing 
Published: July 2023

Objective: To investigate whether mineralized collagen modified polymethyl methacrylate (MC-PMMA) bone cement impacts the implanted vertebral body and adjacent segments and the feasibility of biomechanical properties compared with common bone cement in the treatment of osteoporotic vertebral compression fractures (OVCF).Methods: A healthy volunteer was selected to perform a three-dimensional reconstruction of the T11-L1 vertebral body to establish the corresponding finite element model of the spine, and the changes in the stress distribution of different types of cement were biomechanically analyzed in groups by applying quantitative loads.Results: The stress distribution of the T11-L1 vertebral body was similar between the two bone types of cement under various stress conditions.Conclusion: Mineralized collagen modified bone cement had the advantages of promoting bone regeneration, good biocompatibility, good transformability, and coupling, and had support strength not inferior to common PMMA bone cement, indicating it has good development prospects and potential.
Webcam-use in the NICU-setting from the perspective of Health Care Professionals and its implication for communication with parents
Authors: Stümpel Johanne , Dörrhöfer Annika , Mantell Pauline , Jannes Christiane , Reimer Alinda , Woopen Christiane 
Published: July 2023

BackgroundIn Germany, a growing number of neonatal intensive care units (NICUs) are equipped with webcams. The utilization of webcams in the NICU is gaining greater attention and the impact of this technology can be manifold. However, there has been no definite understanding of its impact. We will highlight the webcam's implications on the communication between parents and Health Care Professionals (HCPs) in German NICUs.Methods20 interviews were conducted with HCPs from three German NICUs between December 2019 and August 2020 according to a qualitative research design. Seven out of them had no webcam experience, whereas for 13 of them, webcam-use is part of their working routine. Interviews were analyzed following Kuckartz's thematic analysis. Findings were assessed in accordance with the NICU Communication Framework.ResultsHCPs consider the webcams as a beneficial addition to the interaction of parents with their infants, as well as the HCP-parent interaction. At the same time, HCPs created new pathways of communication with parents via the webcam. Any negative effects feared by HCPs without webcam experience regarding the communication with parents, including a lasting shift of conversation away from the infant and toward more technical aspects of the webcams, but also an increase in phone calls from parents and an associated increase in workload, could not be confirmed by HCPs with webcam experience.ConclusionThe findings indicate that the implementation of webcams in German NICUs not only has an influence on the communication between parents and HCPs, but it expands communicative pathways. It can be stated that they support tailored communication but are not necessarily sufficient to account for all aspects themselves. The results of this study help to assess the impact of webcams on communication between parents and HCPs and should be applied to strengthen it within NICUs equipped with webcams.Clinical trial registrationThe Neo-CamCare Study is registered at the German Clinical Trial Register. DRKS-ID: DRKS0001775; Date of registration: 05/09/2019.
Automatized localization of induced geothermal seismicity using robust time-domain array processing
Authors: Hering Philip , Lindenfeld Michael , Rümpker Georg 
Published: July 2023

The surveillance of geothermal seismicity is typically conducted using seismic networks, deployed around the power plants and subject to noise conditions in often highly urbanized areas. In contrast, seismic arrays can be situated at greater distances and allow monitoring of different power plants from one central location, less affected by noise interference. However, the effectiveness of arrays to monitor geothermal reservoirs is not well investigated and the increased distance to the source coincides with a decreased accuracy of the earthquake localizations. It is therefore essential to establish robust data processing and to obtain precise estimates of the location uncertainties. Here, we use time-domain array data processing and solve for the full 3-D slowness vector using robust linear regression. The approach implements a Biweight M-estimator, which yields stable parameter estimates and is well suited for real-time applications. We compare its performance to conventional least squares regression and frequency wavenumber analysis. Additionally, we implement a statistical approach based on changepoint analysis to automatically identify P- and S-wave arrivals within the recorded waveforms. The method can be seen as a simplification of autoregressive prediction. The estimated onsets facilitate reliable calculations of epicentral distances. We assess the performance of our methodology by comparison to network localizations for 77 induced earthquakes from the Landau and Insheim deep-geothermal reservoirs, situated in Rhineland-Palatinate, Germany. Our results demonstrate that we can differentiate earthquakes originating from both reservoirs and successfully localize the majority of events within the magnitude range of ML -0.2 to ML 1.3. The discrepancy between the two localization methods is mostly less than 1 km, which falls within the statistical errors. However, a few localizations deviate significantly, which can be attributed to poor observations during the winter of 2021/2022.
Bariatric surgery and its impact on depressive symptoms, cognition, brain and inflammation
Authors: Kotackova Lenka , Marecek Radek , Mouraviev Andrei , Tang Ariana , Brazdil Milan , Cierny Michal , Paus Tomas , Pausova Zdenka , Mareckova Klara 
Published: July 2023

BackgroundObesity has been associated with depressive symptoms and impaired cognition, but the mechanisms underlying these relationships are not well understood. It is also not clear whether reducing adiposity reverses these behavioral outcomes. The current study tested the impact of bariatric surgery on depressive symptoms, cognition, and the brain; using a mediation model, we also examined whether the relationship between changes in adiposity after the surgery and those in regional thickness of the cerebral cortex are mediated by changes in low-grade inflammation (as indexed by C-reactive protein; CRP).MethodsA total of 18 bariatric patients completed 3 visits, including one baseline before the surgery and two post-surgery measurements acquired at 6- and 12-months post-surgery. Each visit consisted of a collection of fasting blood sample, magnetic resonance imaging of the brain and abdomen, and assessment of depressive symptoms and cognition.ResultsAfter surgery, we observed reductions of both visceral fat (p&lt; 0.001) and subcutaneous fat (p&lt; 0.001), less depressive symptoms (p&lt; 0.001), improved verbal reasoning (p&lt; 0.001), and reduced CRP (p&lt; 0.001). Mediation analyses revealed that the relationships between the surgery-related changes in visceral fat and cortical thickness in depression-related regions are mediated by changes in CRP (ab=-.027, SE=.012, 95% CI [-.054, -,006]).ConclusionThese findings suggest that some of the beneficial effects of bariatric surgery on brain function and structure are due to a reduction of adiposity-related low-grade systemic inflammation.
Clinical evaluation of autologous platelet-rich plasma therapy for intrauterine adhesions: a systematic review and meta-analysis
Authors: Tang Ruonan , Xiao Xifeng , He Yunan , Qiu Daner , Zhang Wanlin , Wang Xiaohong 
Published: July 2023

ObjectiveThis meta-analysis aims to evaluate the efficacy and safety of autologous platelet-rich plasma (PRP) administration in reducing adhesion recurrence and improving pregnancy outcomes in patients with intrauterine adhesion (IUA).MethodsWe conducted a comprehensive search of Pubmed, Embase, the Cochrane Library, Web of Science, Scopus, and China National Knowledge Internet (CNKI) from inception to February 10, 2023, without any language or regional restrictions. We used random-effects models to assess odds ratios (OR) and weight mean differences (WMD) with 95% confidence intervals (CI).ResultsOur meta-analysis included a total of 730 patients from 10 clinical studies (6 RCTs and 4 non-RCTs). The results showed that PRP administration significantly increased endometrial thickness (WMD = 0.79, 95% CI: 0.40–1.19; P &lt; 0.001; I2 = 0.0%), menstrual volume (WMD = 2.96, 95% CI = 2.30–3.61; P &lt; 0.001; I2 = 0.0%), and days of menstruation (WMD = 1.13, 95% CI = 0.86–1.41; P &lt; 0.001; I2 = 0.0%). Additionally, the clinical pregnancy rate was also improved (OR = 1.82, 95% CI: 1.19-2.78; P = 0.006; I2 = 0.0%). However, there was insufficient evidence to reach a conclusion regarding the effects of PRP on the recurrence rate of moderate to severe IUA, changes in AFS scores, miscarriage rate, and live birth rate.ConclusionsOur analysis confirms that autologous PRP is an effective treatment for IUA. However, the limited sample size suggests that the results should be interpreted with caution. Therefore, larger and well-designed studies are necessary in the future to confirm these findings and explore the optimal PRP dosing regimens further.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO, identifier CRD42023391115.
Vitamin D supplementation reduced blood inflammatory cytokines expression and improved graft function in kidney transplant recipients
Authors: Bai Yang-Juan , Li Ya-Mei , Hu Shu-Meng , Zou Yuan-Gao , An Yun-Fei , Wang Lan-Lan , Shi Yun-Ying 
Published: July 2023

BackgroundChronic allograft dysfunction(CAD) is the leading cause of graft loss in kidney transplant recipients (KTRs). Inflammatory process is believed to be one of the major contributors to CAD. The aim of this study is to explore the anti-inflammatory effect of vitamin D (VD) supplementation in KTRs and its role in the graft function improvement(protection).MethodsA retrospective cohort of 39 KTRs with chronic antibody mediated rejection(CAMR)or stable renal function and a prospective cohort of 42 KTRs treated or untreated with VD were enrolled. Serum levels of vitamin D metabolism and serum inflammatory cytokines, renal graft function, and routine blood biomarkers were tested and dynamically tracked within 12 months post-transplant.ResultsCompared with the stable group, the CAMR group exhibited significantly elevated serum levels of inflammatory cytokines IL-1β, IFN-γ, IL-2, IL-10, IP-10, and HMGB1 (P &lt;0.05). The supplementation of vitamin D effectively increased the serum concentration of vitamin D in kidney transplant recipients (KTRs) in the treated group. During the course of treatment, the treated group exhibited a gradual increase in eGFR levels, which were significantly higher than those observed in the untreated group at 12 months post-transplant (p&lt;0.05). Notably, as eGFR improved, there was a significant decrease in levels of IL-1β, IFN-γ, IL-2, IL-10, IP-10 and HMGB1 in the treated group compared to the untreated group (P&lt;0.05).ConclusionThis study confirmed that immune-inflammation is a crucial factor in the development of CAD in KTRs.VD deficiency impairs its anti-inflammatory activity. By assisting in the regulation of excessive immune inflammation and restoration of immune homeostasis, effective VD supplementation contributes to protection and maintenance of graft function in KTRs.