bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring recovery of joints after bleeding: Physical examination and ultrasound are complementary
Authors: van Leeuwen Flora H. P. , Fischer Kathelijn , Foppen Wouter , van Vulpen Lize F. D. , Timmer Merel A. 
Published: April 2023

AbstractAimTraditionally, recovery after a joint bleed in people with bleeding disorders is evaluated by clinical symptoms. Following a bleed, however, asymptomatic joints may still show synovial hypertrophy and effusion on ultrasound. We evaluated the duration of full recovery from a joint bleed. Additionally, we determined how recovery differed when assessed by physical examination and ultrasound.MethodsIn this retrospective cohort study, we investigated joint bleeds in elbows, knees and ankles of people with haemophilia or Von Willebrand disease who attended the Van Creveldkliniek between 2016 and 2021. Physical examination (warmth, swelling, range of motion and gait) and ultrasound (effusion and synovial hypertrophy) were performed within 7 days after the onset of the bleed, 1 week after the first examination and monthly thereafter until patients had recovered fully. Joint bleeds were treated in line with the current international treatment guidelines.ResultsWe evaluated 30 joint bleeds in 26 patients. The median recovery time was 1 month (range 0.3‐5 months). In 47% of the joint bleeds, the recovery took longer than 1 month. The moment of recovery based on physical examination and ultrasound differed in 27% of bleeds. Both persistent abnormalities at physical examination in joints with normalized ultrasounds and persistent ultrasound findings in clinically recovered joints occurred.ConclusionJoint bleed recovery can take long and recovery times differed per bleed. Recovery differed when assessed by physical examination or ultrasound. Therefore, both should be used to closely monitor recovery of joint bleeds and offer personalized care.
Notes on historiography of photographs from India
Authors: Roychoudhuri Ranu 
Published: April 2023

AbstractDespite its long and layered histories, critical analyses of photography in India began rather late and remain comparatively limited in number. However, the burgeoining scholarship in the field illuminates photography's role in conditioning modern South Asian experiences, while also highlighting the global character of the medium that complicate the unmarked history of photography. Three intertwined historiographical threads are influential in narrating the colonial Indian camera cultures. The first thread emphasized descriptive histories, the second thread debated cultural essentialism, while the third thread inquired into myriad photographic genres to rethink colonialism. An inquiry into these three threads helps reflect on the intellectual scope of photographs from colonial India, while also directing to future archival and analytical possibilities.
A multicenter evaluation of the Technoscreen ADAMTS13 activity semi‐quantitative screening test for thrombotic thrombocytopenic purpura diagnosis and exclusion
Authors: Stephenson Jared , Chapman Kent , Mohammed Soma , Zebeljan Diane , Ahuja Monica , Donikian Dea , Pasalic Leonardo , Motum Penelope , Hsu Danny , Brighton Timothy , Favaloro Emmanuel J. 
Published: April 2023

AbstractIntroductionThrombotic thrombocytopenic purpura (TTP) is a rare but potentially fatal microangiopathy, with an untreated mortality rate of around 90%. TTP is caused by severe deficiency in ADAMTS13, which results in accumulation of ultra large von Willebrand factor multimers, triggering a consumptive thrombocytopenia, microangiopathic hemolytic anemia and end‐organ dysfunction and damage. Demonstration of severe ADAMTS13 deficiency is diagnostic for TTP, but long turnaround times for quantitative activity testing often necessitates empirical plasma exchange and/or caplacizumab treatment.MethodsMultisite (n = 4) assessment of the Technoscreen ADAMTS13 activity assay (semi‐quantitative flow through screening assay) for diagnosis/exclusion of TTP compared to current standard practice of quantitative assays (ELISA or chemiluminescence AcuStar).ResultsA total of 128 patient samples were analyzed, with quantitative ADAMTS13 values ranging from 0% to 150%. The Technoscreen assay demonstrated high sensitivity and negative predictive value (NPV) for ADAMTS13 deficiency, but low specificity and positive predictive value (PPV), especially with one lot of reagent. Good inter‐observer reliability was demonstrated. Excluding one possibly compromised batch and other test failures, results of 80 samples yielded sensitivity of 100% (95% CI = 84–100), specificity of 90% (80–95), PPV 77% (58–89) and NPV 100% (93–100).ConclusionThe Technoscreen assay appears to be a reliable screening test for ADAMTS13 activity to exclude TTP in routine clinical practice. However, the assay falsely identified ADAMTS13 deficiency in many cases, partially batch related, which mandates confirmation with a quantitative assay, as well as initial assessment of kits as ‘fit for purpose’ prior to use for patient testing.
Late Cenozoic evolution of the latitudinal diversity gradient
Authors: Crame J. Alistair 
Published: April 2023

AbstractAimThe Late Cenozoic flourishing of polar marine ecosystems, just when temperatures were reaching their lowest levels, has always seemed anomalous. Such an observation is coupled with an increasing volume of molecular phylogenetic evidence to indicate that some polar taxa radiated at exceptionally high evolutionary rates. The canonical latitudinal diversity gradient (LDG) may not be underpinned by a parallel gradient in evolutionary rates. This study provides a review of this critical question.LocationA variety of polar – tropical comparisons are made, with some emphasis on the Southern Ocean.TaxaBoth marine and terrestrial taxa are used, with some emphasis on marine Mollusca.MethodsHigh – low latitude comparisons of evolutionary rates over the last 66 Myr are made using two approaches: rates derived from molecular phylogenies, and rates derived from the fossil record. For the former of these data are taken from various marine and terrestrial taxa, and for the latter use is made of the excellent fossil record of marine Mollusca.ResultsFor approximately the first half of the Cenozoic era (i.e., 66 Ma onwards) there is strong palaeontological evidence to suggest that the global LDG developed in a conventional way, with higher rates of origination in the tropics than at the poles. However, there then appears to have been a marked change in the latter half of the Cenozoic when origination rates increased in the high‐latitude and polar regions. The modern latitudinal diversity gradient may be a fossil feature that formed in the Early Cenozoic.Main ConclusionsAs the extra‐tropical regions expanded through the Cenozoic they provided increasingly more ecological opportunities for a wide variety of marine and terrestrial taxa. Substantially lower temperatures in the polar regions were clearly not an obstacle to spectacular evolutionary radiations such as that based on the krill ecosystem.
Watchman device migration and embolization: A report from the NCDR LAAO Registry
Authors: Friedman Daniel J. , Freeman James V. , Zimmerman Sarah , Tan Zhen , Pereira Lucy , Faridi Kamil F. , Curtis Jeptha P. 
Published: April 2023

AbstractIntroductionIncomplete anchoring of the Watchman left atrial appendage closure (LAAO) device can result in substantial device migration or device embolization (DME) requiring percutaneous or surgical retrieval.MethodsWe performed a retrospective analysis of Watchman procedures (January 2016 through March 2021) reported to the National Cardiovascular Data Registry LAAO Registry. We excluded patients with prior LAAO interventions, no device released, and missing device information. In‐hospital events were assessed among all patients and postdischarge events were assessed among patients with 45‐day follow‐up.ResultsOf 120 278 Watchman procedures, the in‐hospital DME rate was 0.07% (n = 84) and surgery was commonly performed (n = 39). In‐hospital mortality rate was 14% among patients with DME and 20.5% among patients who underwent surgery. In‐hospital DME was more common: at hospitals with a lower median annual procedure volume (24 vs. 41 procedures, p < .0001), with Watchman 2.5 versus Watchman FLX devices (0.08% vs. 0.04%, p = .0048), with larger LAA ostia (median 23 vs. 21 mm, p = .004), and with a smaller difference between device and LAA ostial size (median difference 4 vs. 5 mm, p = .04). Of 98 147 patients with 45‐day follow‐up, postdischarge DME occurred in 0.06% (n = 54) patients and cardiac surgery was performed in 7.4% (n = 4) of cases. The 45‐day mortality rate was 3.7% (n = 2) among patients with postdischarge DME. Postdischarge DME was more common among men (79.7% of events but 58.9% of all procedures, p = .0019), taller patients (177.9 vs. 172 cm, p = .0005), and those with greater body mass (99.9 vs. 85.5 kg, p = .0055). The rhythm at implant was less frequently AF among patients with DME compared to those without (38.9% vs. 46.9%, p = .0098).ConclusionWhile Watchman DME is rare, it is associated with high mortality and frequently requires surgical retrieval, and a substantial proportion of events occur after discharge. Due to the severity of DME events, risk mitigation strategies and on‐site cardiac surgical back‐up are of paramount importance.
Does vestibular incision improve the outcomes of vestibular incision subperiosteal tunnel technique: A randomized clinical trial for treatment of multiple adjacent type 1 gingival recession
Authors: Chen Ziyuan , Zhong Jinsheng , Xie Ying , Fan Keang , Zhou Shuangying , Ouyang Xiangying 
Published: April 2023

AbstractObjectiveThe purpose of this study was to compare the clinical outcomes of vestibular incision subperiosteal tunnel technique (VISTA) and tunnel approach combined with connective tissue graft (CTG) for treatment of type 1 (RT1) multiple gingival recession.Materials and MethodsTwenty‐four patients with a total of 59 nonmolar recession teeth were randomly allocated to VISTA + CTG or Tunnel + CTG group. Recession depth and width, probing depth, clinical attachment level, width of keratinized tissue, gingival thickness, flap tension, mean root coverage (MRC), complete root coverage (CRC), patient‐centered, and esthetic outcomes (root coverage esthetic scores, RES) were assessed at baseline and 12 months after surgery.ResultsAt 12 months, MRC of 91.13 ± 16.96% and 91.40 ± 13.53%, CRC of 70.97% and 67.86% were observed for VISTA + CTG and Tunnel + CTG group respectively, with no significant difference between the two groups (p > 0.05). High RES of 8.52 ± 1.46 and 8.82 ± 1.44 was obtained in VISTA + CTG and Tunnel + CTG group respectively, without showing a significant difference (p = 0.245), while less scar formation was observed in Tunnel + CTG group (p < 0.01).ConclusionsBoth procedures were effective for root coverage in RT1 multiple gingival recession at 12 months. Better esthetic result with less scar formation was obtained in tunnel approach combined with CTG without vestibular incision. (Registration number: ChiCTR‐INR‐16007845, registered on 19/12/2015, http://www.chictr.org.cn).Clinical SignificanceVISTA + CTG and Tunnel + CTG were both effective for root coverage in RT1 multiple gingival recession, with satisfying esthetic outcomes. However, it is suggested in critical esthetic areas, treatment options of making vertical incisions should be carefully considered.
Circular RNA circTNIK promotes tumor progression and metastasis in gastric cancer by regulating ZEB2
Authors: Chen Nuo , Hu Yan , Huang Ren‐Ze , Chen Dong‐Liang 
Published: April 2023

AbstractBackground and AimTumor progression and distant metastasis are the main causes of deaths in gastric cancer. Growing evidence revealed that circular RNAs (circRNAs) play critical role in the pathology of malignant disease, the role of circRNAs in gastric cancer progression and metastasis is still unknown.MethodsDifferentially expressed circRNAs was identified by circRNA microarray and validated by quantitative reverse transcription polymerase reaction. The biological function of circTNIK was evaluated by in vitro and in vivo experiments after ectopic expression or siRNA mediated knockdown of circTNIK. The interaction between circTNIK and miR‐138‐5p was determined by luciferase activity assay, RNA immunoprecipitation, and fluorescence in situ hybridization assays.ResultscircTNIK rather than linear TINK mRNA was significantly upregulated in gastric cancer tissues, cell lines compared with normal controls. Higher circTNIK expression was correlated with aggressive tumor phenotypes and poor overall survival in gastric cancer patients. Ectopic circTNIK expression promoted cell proliferation, invasion, tumorigenesis, and metastasis in gastric cancer cells whereas knockdown of circTNIK inhibited cell proliferation, invasion, tumorigenesis, and metastasis in gastric cancer cells. Importantly, circTNIK functions as a molecular sponge for miR‐138‐5p to regulate the expression of ZEB2.ConclusionsOverall, our study demonstrates how circTNIK regulates gastric cancer progression and metastasis by sponging miR‐138‐5p to modulate the expression of ZEB2. CircTNIK might be used as a prognostic biomarker in gastric cancer patients.
Social and structural determinants of recovery: The impact of race
Authors: Mumba Mercy Ngosa , Brantley Shakia G. , Cross Allison 
Published: April 2023

AbstractRelapse rates for substance use disorders (SUDs) after treatment are as high as 50%. Evidence suggests that social and structural determinants of recovery influence these outcomes. Important domains to consider include economic stability, educational access and quality, healthcare access and quality, neighborhood and built environment, and social and community context are the major domains of social determinants of health. All these factors influence people's ability to reach their highest health potential. However, race and racial discrimination often compound the negative effects of these factors on substance use treatment outcomes. Moreover, research is urgently needed to examine the specific mechanisms through which these issues influence SUD and SUD outcomes.
The Influence of Native Phonology, Allophony, and Phonotactics on Nonnative Lexical Encoding: A Vocabulary Training Study
Authors: Zheng Qi , Gor Kira 
Published: April 2023

AbstractSecond language (L2) speakers often experience difficulties in learning words with L2‐specific phonemes due to the unfaithful lexical encoding predicted by the fuzzy lexical representations hypothesis. Currently, there is limited understanding of how allophonic variation in the first language (L1) influences L2 phonological and lexical encoding. We report how the Mandarin Chinese L1 phonemic inventory and allophonic variation subject to phonotactic constraints predict phonological encoding problems for novel L2 English words with the /v/–/w/ contrast. L1 English and L1 Chinese participants speaking two varieties of Mandarin Chinese differing as to the presence of [ʋ]–[w] allophonic variation for the /w/ phoneme participated in a vocabulary learning task. The novel L2 words with the /v/–/w/ contrast were systematically less robustly encoded than the control words on the day of training and 24 hours later. The degree of fuzziness in lexical representations was jointly predicted by L1 allophonic variation subject to phonotactic constraints and L2 phonological categorization.
A Comparison of Radiographic Outcomes after Total Hip Arthroplasty between the Direct Lateral Approach and Posterior Lateral Approach with EOS 2D/3D X‐Ray Imaging System
Authors: Xie Rui , Huang Jun , Wu Qian , Qian Yu‐fan , Jiang Dinghua , Li Lisong , Huang Lixin 
Published: April 2023

ObjectiveThe classical approaches for total hip arthroplasty (THA) are the direct lateral approach (DLA) and posterior lateral approach (PLA). There are few studies comparing implant orientation with these two approaches, and the impact of surgical approaches on implant orientation remains controversial. With the rise of the EOS imaging system, we aimed to use it to identify the differences between and factors associated with implant orientation after THA using DLA and PLA.MethodsIn our department from January 2019 to December 2021, 321 primary unilateral THAs that used PLA and DLA were enrolled. A total of 201 patients who received PLA and 120 patients who received DLA were included in this study. Two blinded observers measured each case using EOS imaging data. Postoperative imaging metrics and other relevant influencing factors of the two surgical approaches were compared. Postoperative imaging metrics, including the anteversion and inclination of the cup, anteversion of the stem, and combined anteversion were measured based on EOS. Other relevant influencing factors included age, approach, gender, laterality, BMI, anterior pelvic plane inclination, femoral head diameter, femoral offset, lateral pelvic tilt, pelvic incidence, pelvis axial rotation, sacral slope, sagittal pelvic tilt, and surgery time. Multiple linear regression analyses were performed to identify the predictors of acceptability for each imaging data point.ResultsNo dislocation was found in the 321 patients who underwent primary THA during this period. The mean anteversion and combined anteversion of the cups using the DLA were 21.33° ± 17.31° (−51.7°–60.8°) and 33.71° ± 20.85° (−38.8°–77.6°) and PLA were 25.34° ± 12.76° (−5.5°–57.0°) and 42.37° ± 18.85° (−8.7°–84.7°), respectively. The DLA group had smaller anteversion (p = 0.038) and combined anteversion (p < 0.001). We found that surgical approach (p < 0.05), anterior pelvic plane inclination (p < 0.001), gender (p < 0.001), and femoral head diameter (p < 0.001) were important factors affecting acetabular cup anteversion (R2 = 0.375) and combined anteversion (R2 = 0.525).ConclusionsIn total hip arthroplasty, different prosthesis installation directions should be made according to different surgical approaches. Compared with the direct lateral approach, the acetabular anteversion can be intentionally enlarged when using the posterolateral approach. Surgical approach, anterior pelvic plane inclination (APPI), gender, and femoral head diameter were significant predictors of prosthesis orientation. The anterior pelvic plane inclination may be a useful standard for assessing the position of the prosthesis using EOS.
Conceptualizing Landscapes Through Language: The Role of Native Language and Expertise in the Representation of Waterbody Related Terms
Authors: Purves Ross S. , Striedl Philipp , Kong Inhye , Majid Asifa 
Published: April 2023

AbstractLandscapes are essential to human life: they provide a multitude of material (food, water, pollination) and nonmaterial (beauty, tranquility, recreation) values. Their importance is enshrined in international conventions and treaties, committing signatories to protecting, monitoring, and managing all landscapes. Yet, relatively little is known about how people conceptualize “landscape” and its constituents. There is emerging evidence that conceptualizations of landscape entities may influence landscape management. This in turn raises the question as to how people speaking different languages, and with differing levels of expertise, may differ in conceptualizing landscape domains as a whole. In this paper, we investigated how people conceptualize landscape‐related terms in a specific domain—waterbodies—by comparing German and English‐speaking experts and nonexperts. We identified commonly used waterbody terms in sustainability discourses in both languages, and used those terms to collect sensory, motor, and affective ratings from participants. Speakers of all groups appear to conceptualize the domain of waterbody terms in comparable ways. Nevertheless, we uncovered subtle differences across languages for nonexperts. For example, there were differences in which waterbodies were associated with calm happiness in each language. In addition, olfaction seemingly plays a role in English speakers’ conceptualization of waterbodies, but not German speakers. Taken together, this suggests the ways in which people relate to landscape although shared in many respects may also be shaped in part by their specific language and culture.
Study of Cross-Scale Micro-Motion Wear Characteristics of Metallic Rubber
Authors: Bai Yonggang , Huang Zhou , Shi Xianjie , Guo Zhuotao , Huang Zihao , Ren Zhiying 
Published: April 2023

Abstract
Metal rubber (MR) is a kind of elastic porous material with a complex and disordered internal structure, which results in wear characteristics that can only rely on tests but cannot meet the engineering application. This paper presents an exciting method for studying wear characteristics based on its virtual fabrication technology. By developing the intricate internal multipoint random contact mesh model of MR, a virtual real-time dynamic tracking contact point in a different state is captured. A thorough investigation is conducted into the contact point properties, point distribution, and the interaction of discrete contact points in MR interior space. Accordingly, a cross-scale micro-motion wear study method from micromorphology to macroscopic performance is proposed. The continuous wear cycle of MR is discretized into multiple single-turn metal wire elements by applying the principle of equal spacing. A statistical model of internal contact point wear of MR at the microlayer is developed considering the metal wire’s single-turn fretting wear prediction model. The cumulative prediction model of macroscopic wear damage of MR is based on the superposition of micro-element interval. Finally, the difference between the mass loss and that obtained from the simulation analysis after performing dynamic loading tests at different cycles was studied and found to be insignificant.
Dimensional Discussion of Traction Force Vector on Ball/Raceway Interface and Study of Bearing Dynamic Behavior
Authors: Ma Shuaijun , Yin Yanjing , Zhu Linbo , Yan Ke , Zhu Yongsheng 
Published: April 2023

Abstract
As a crucial component, rolling bearings directly determine the reliability of rotating equipment. However, current dynamic models for predicting the bearing performance either ignore the velocity and stress dispersion at the ball/raceway interface or fail to consider the spin moment generated within the interface. To address this issue, the discrete features of the velocity and stress distribution are considered in this paper, and the micro-element approach is used to construct formulas to obtain the traction vectors in two and three dimensions, respectively. Two bearing dynamic models are further developed for these two types of equations: one model considers the spin moment at the interface owing to unequal contact angles between the ball and the two raceways, while the other model ignores this moment. The reliability of these models is validated by comparison with experimental test results, including cage speed and oil film thickness. The predictions from the quasi-static model are used as theoretical values to compare the ability of the two models to simulate bearing performance under different operating conditions. The results show that the prediction results of the model considering the spin moment are closer to the theoretical values than those of the model ignoring this moment. However, the moment increases the friction at the ball/raceway interface, causing this model to underestimate the extent of bearing sliding.