bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Mixed Polymethylmethacrylate and Hydroxyapatite on Viability of Stem Cell from Human Exfoliated Deciduous Teeth and Osteoblast
Authors: Saskianti Tania , Purnamasari Shinta , Pradopo Seno , Nugraha Alexander Patera , Prahasanti Chiquita , Ernawati Diah Savitri , Kanawa Masami 
Published: June 2023

Abstract
Objectives Stem cell from human exfoliated deciduous teeth (SHED) has great potential for bone tissue engineering and cell therapy for regenerative medicine. It has been combined with biomaterials such as mixed of polymethylmethacrylate (PMMA) and hydroxyapatite (HA) as candidates for synthetic bone graft biomaterial. The aim of this study was to analyze the toxicity test of mixed PMMA-HA scaffold seeded with SHED and osteoblast in vitro.
Materials and Methods SHED was isolated from the pulp of noncarious deciduous teeth and osteoblast cells were cultured, and exposed to PMMA-HA scaffolds with three concentration groups: 20/80, 30/70, and 40/60 for 24 hours. Cytotoxicity test was performed by MTT assay to cell viability.
Statistical Analysis Data were analyzed using IBM SPSS Statistics 25, one-way analysis of variance followed by least significant difference test, considering the level of significance p-value less than 0.05
Results The percentage of SHED's viability was best in the PMMA-HA group with concentrations of 20/80, followed by 30/70, and 40/60 with 87.03, 75.33, and 65.79%, respectively. The percentage of osteoblast cell's viability was best in the PMMA-HA group with concentrations of 20/80, followed by 30/70, and 40/60 with 123.6, 108.36, and 93.48%, respectively.
Conclusions Mixed PMMA-HA was not toxic for the SHED and osteoblast. This characteristic is the initial requirement to be proposed as an alternative material for healing alveolar bone defects. In vivo animal research is mandatory to confirm the use of PMMA-HA on the alveolar defect model.
Effects of Hemogram Parameters on Remission Durations in Self-Limited Epilepsy with Centrotemporal Spikes
Authors: Günay Çağatay , Sarıkaya Uzan Gamze , Özsoy Özlem , Hız Kurul Semra , Yiş Uluç 
Published: June 2023

AbstractThe hemogram parameters have been extensively discussed in numerous diseases, including epilepsy, for their diagnostic and prognostic values. We aimed to investigate the impact of hemogram parameters, namely, the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) at the time of the first seizure on the remission durations of the patients with self-limited epilepsy with centrotemporal spikes (SeLECTS). This retrospective study was conducted on patients with SeLECTS with a minimum follow-up of 2 years. We assessed the hemogram parameters obtained from the venous blood samples collected from the patients upon admission. The duration of remission was categorized into two groups for further data analysis: those with a remission period less than 2 years and those with a remission period of more than 2 years. This study involved 122 patients with SeLECTS, of which 85% (n = 102) had remission durations of ≤2 years. The analysis revealed that patients with remission durations exceeding 2 years had a significantly higher median leukocyte (p = 0.009), neutrophil (p < 0.001), and platelet (p < 0.001) counts. Additionally, higher levels of NLR and PLR were observed in patients with longer-term remission (p < 0.001). However, there were no significant differences between the two groups in terms of lymphocyte count, monocyte count, mean platelet volume, or LMR. Leukocyte, neutrophil, platelet, NLR, and PLR counts have shown potential as predictive indicators of remission times in patients with SeLECTS. Neurologists can potentially find value in these easily accessible parameters when evaluating the future trajectory of patients with SeLECTS.
Cervical Osmotic Dilators versus Dinoprostone for Cervical Ripening during Labor Induction: A Systematic Review and Meta-analysis of 14 Controlled Trials
Authors: Al-Matary Abdulrahman , Alsharif Saud A. , Bukhari Ibtihal A. , Baradwan Saeed , Alshahrani Majed S. , Khadawardi Khalid , Badghish Ehab , Albouq Bayan , Baradwan Afnan , Abuzaid Mohammed , Al-Jundy Haifa , Alyousef Abdullah , Ragab Wael S. , Abu-Zaid Ahmed 
Published: June 2023

Objective This study aimed to conduct a systematic review and meta-analysis of all randomized and nonrandomized controlled trials (RCTs and NCTs, respectively) that explored the maternal–neonatal outcomes of cervical osmotic dilators versus dinoprostone in promoting cervical ripening during labor induction.
Study Design Six major databases were screened until August 27, 2022. The quality of included studies was evaluated. The data were summarized as mean difference or risk ratio (RR) with 95% confidence interval (CI) in a random-effects model.
Results Overall, 14 studies with 15 arms were analyzed (n = 2,380 patients). Ten and four studies were RCTs and NCTs, respectively. The overall quality for RCTs varied (low risk n = 2, unclear risk n = 7, and high risk n = 1), whereas all NCTs had good quality (n = 4). For the primary endpoints, there was no significant difference between both groups regarding the rate of normal vaginal delivery (RR = 1.04, 95% CI: 0.95–1.14, p = 0.41) and rate of cesarean delivery (RR = 1.04, 95% CI: 0.93–1.17, p = 0.51). Additionally, there was no significant difference between both groups regarding the mean change in Bishop score and mean time from intervention to delivery. The rate of uterine hyperstimulation was significantly lower in the cervical osmotic dilator group. For the neonatal outcomes, during cervical ripening, the rate of fetal distress was significantly lower in the cervical osmotic dilator group. There was no significant difference between both groups regarding the mean Apgar scores, rate of meconium-stained amniotic fluid, rate of umbilical cord metabolic acidosis, rate of neonatal infection, and rate of neonatal intensive care unit admission.
Conclusion During labor induction, cervical ripening with cervical osmotic dilators and dinoprostone had comparable maternal–neonatal outcomes. Cervical osmotic dilators had low risk of uterine hyperstimulation compared with dinoprostone. Overall, cervical osmotic dilators might be more preferred over dinoprostone in view of their analogous cervical ripening effects, comparable maternal–neonatal outcomes, and lack of drug-related adverse events.
Key Points
Prenatal Diagnosis of Chromosomal Mosaicism in 18,369 Cases of Amniocentesis
Authors: Kang Han , Wang Lingxi , Xie Yamei , Chen Yifei , Gao Chonglan , Li Xingyu , Hu Yu , Liu Qingsong 
Published: June 2023

Objective The prenatal diagnosis of chromosomal mosaicism is fraught with uncertainty. Karyotyping, chromosomal microarray analysis (CMA), and fluorescence in situ hybridization (FISH) are three commonly used techniques. In this study, we evaluated these techniques for the prenatal diagnosis of chromosomal mosaicism and its clinical outcome.
Study Design A retrospective review of mosaicism was conducted in 18,369 pregnant women from January 2016 to November 2021. The subjects underwent amniocentesis to obtain amniotic fluid for G-band karyotyping with or without CMA/FISH. Cases diagnosed with chromosomal mosaicism were selected for further analysis.
Results In total, 101 cases of chromosomal mosaicism were detected in 100 pregnant women (0.54%, 100/18,369). Four were lost during follow-up, 61 opted to terminate their pregnancy, and 35 gave birth to a healthy singleton or twins. Among these 35 cases, postnatal cytogenetic testing was performed on eight and two exhibited mosaicism; however, nothing abnormal was observed in the postnatal phenotype follow-up. Karyotyping identified 96 incidents of chromosomal mosaicism including 13 with level II mosaicism and 83 with level III mosaicism, FISH identified 37 cases of mosaicism, and CMA identified 17. The most common form of chromosomal mosaicism involved monosomy X, of which the mosaic fraction in cultured karyotyping appeared higher or comparable to uncultured FISH/CMA (p < 0.05). Discordant mosaic results were observed in 34 of 101 cases (33.7%), most of which resulted from the detection limit of different techniques and/or the dominant growth of a certain cell line.
Conclusion Based on the postnatal follow-up results from the babies born, we obtained a more hopeful result for the prognosis of chromosomal mosaicism. Although karyotyping was the most sensitive method for detecting chromosomal mosaicism, artifacts and bias resulting from culture should be considered, particularly for sex chromosomal abnormalities involving X monosomy, in which the combination with uncultured FISH was necessary.
Key Points
New Zealand pharmacists’ views regarding the current prescribing courses: questionnaire survey
Authors: Ghabour Mariam , Morris Caroline , Wilby Kyle , Smith Alesha 
Published: June 2023

Introduction New Zealand pharmacists must complete a joint prescribing course offered by Otago and Auckland universities only, to be qualified as pharmacist prescribers. Aim To identify knowledge and perceptions of New Zealand registered pharmacists, who are not pharmacist prescribers, on: pharmacist prescribing roles, courses and perceived barriers and facilitators to course uptake. Methods Participants comprised registered practising New Zealand pharmacists (n = 4025), across all New Zealand regions. Invitations to participate in a questionnaire survey were sent in March 2021. Data were analysed using thematic analysis and descriptive statistics. Results The response rate was 12% (482/4025), with 94% community pharmacists. Almost two-thirds (65%) had over 10 years of working experience. Nearly all (95%) agreed that pharmacist prescribing would improve healthcare delivery in New Zealand. Most reported that barriers to pharmacist prescribing course uptake were funding, lack of institutional support, up-to-date pharmacological/pharmaceutical knowledge, and 2 years of experience in collaborative health team prerequisites for enrolment, finding medical supervisors, and lack of remuneration for prescribing roles. Discussion Pharmacist prescribing in New Zealand is still in its growing phase. Optimising uptake of prescribing courses and role requires a multi-level approach including all stakeholders. Government/policymakers should consider pharmacist prescribing training and remuneration in their funding plans. Employing institutions should provide required time and human resources (staff backfills). Training providers should consider methods of course delivery and assessment that are suitable for trainees in full-time employment.
The expression of hate speech against Afro-descendant, Roma, and LGBTQ+ communities in YouTube comments
Authors: Carvalho Paula , Caled Danielle , Silva Cláudia , Batista Fernando , Ribeiro Ricardo 
Published: June 2023

Abstract
This paper addresses the specificities of online hate speech against the Afro-descendant, Roma, and LGBTQ+
communities in Portugal. The research is based on the analysis of CO-HATE, a corpus composed of 20,590 YouTube comments, which
were manually annotated following detailed guidelines created for that purpose. We applied methods from corpus
linguistics to assess the prevalence of overt and covert hate speech, counter-speech, and offensive speech, considering different
grounds of discrimination, and to investigate the main linguistic and rhetorical strategies underlying hatred messages. The
research results highlight the importance of tackling covert hate speech, a recurring phenomenon often anchored in irony and
fallacious argumentation, including the emotional appeal to fear and the implicit call to action. We believe this study will aid
in advancing the analysis of online hate speech, while promoting the development of efficient automated detection models,
specifically regarding the Portuguese language.
Lost in transition
Authors: Imer Lisbeth M. , Vasshus Krister S.K. 
Published: June 2023

AbstractIn 2020 a large gold hoard was discovered in Vindelev, Jutland, Denmark, containing almost 800g of gold. Among the hoard’s artefacts are six runic bracteates discussed here. Two bracteates give important contributions to central discussions in bracteate research. IK 737 is similar to the well-known bracteate IK 58 from Funen. It demonstrates that the much-discussed sequence does not readhouaz, but ratherhoraz,weakening its direct connection to Óðinn through one of his many bynames. IK 738 has one of the best executed inscriptions on a bracteate. The inscription consists of 34 runes (including bind-runes) and its final sequence ‘He/who [is] Óðin’s man’ is a crucial contribution to the discussion of who is depicted on the bracteates, Óðinn or a king? The wording rather indicates the latter.
Conventional breeding of Pacific Island staple crops: A paradox
Authors: Lebot Vincent , Komolong Birte , Labouisse Jean-Pierre , Lawac Floriane , Kaoh Juliane , Waqainabete Logotonu Meleisea , Sukal Amit , Jackson Grahame 
Published: June 2023

Abstract
The Pacific Islands (Melanesia, Micronesia, Polynesia) were the last region in the world to be colonized by modern humans. In their migrations, they dispersed asexually propagated food plants that were first domesticated in Melanesia and exposed them to further selection in diverse insular environments. Later, staple food crops were introduced from South America. In our search for research on genetic resources characterization and breeding conducted between 1950 and 2022, we retrieved 338 references on 13 crop species. All studies were examined, and a review is presented here. Relatively few were on genetic improvement (92 references) compared to those on morphological diversity (246 references). The paradox is that the Pacific is considered a region exposed to the climatic crisis, perhaps more vulnerable than any other region in the world. This paradox is surprising when we consider that most people in the Pacific are growing staple food crops, for household use and/or for local markets, and occasionally for export. In some countries, it involves more than 75% of the population with a considerable contribution to gross domestic product (GDP). Plant breeding has not been considered a priority to mitigate against forthcoming changes in climate, which is likely to be detrimental to crops with a narrow genetic base. We suggest several possible reasons and that conventional plant breeding should be given high priority based on new approaches that include geographical distribution of allelic diversity.
Inverse problems for constrained parabolic variational-hemivariational inequalities
*
Authors: Migórski Stanisław , Cai Dong-ling , Xiao Yi-bin 
Published: June 2023

Abstract
In this paper we study a novel class of inverse problems for parabolic variational–hemivariational inequalities with a unilateral constraint. A theorem on the well-posedness for weak solution is established. Based on a new continuous dependence result, we prove the nonemptiness and stability of the set of optimal solutions to the corresponding inverse problems. We illustrate the results by a quasistatic nonsmooth frictional viscoelastic contact problem with a unilateral constraint for which we derive results on the unique weak solvability, and existence and stability of solutions to the associated inverse problems.
Temperature effects on electric charge transport processes and electron emission in PBS–clay nanocomposites submitted to electron bombardment
Authors: Taktak Sirine , Fakhfakh Slim , Rondot Sébastien , Tara Ahmed , Jbara Omar 
Published: June 2023

Abstract
The effects of isothermal conditions on the charge transport processes and electron emission properties of polybutylene succinate (PBS) nanocomposites with different nanoclay content are investigated. The temperature range used (20 °C–80 °C) is close to the working conditions of materials used in many applications (insulation, sensors). These effects are highlighted using an appropriate device placed in a scanning electron microscope, allowing measurement of induced current in an electron-irradiated specimen. The experimental results show that the rise in temperature involves a decrease in the charging ability and an increase in the conductivity of PBS nanocomposites. The mobility of charge carriers and its thermal dependency deduced during the discharge step were found to be lower for the nanocomposites. A qualitative analysis, expressed to understand these observations, is based on the determination of the electron trap energy distribution (i.e. density of occupied states). Secondary electron emission yield decreased with increasing temperature. The results help us envision a new class of insulators with improved electrical performance. The operating thermal stress, combined with the absence of trapped charges, allows a reduction of electrical and thermal aging and consequently ensures the long-term reliability of the insulators (for instance under High Voltage).
First principles study on magnetic anisotropy of 5d transition metal doped graphdiyne
Authors: Gao Peiyan , Zhong Yi , Xu Lanqing , Zheng Yongping , Huang Zhigao 
Published: June 2023

Abstract
The exceptional porous architecture of graphdiyne (GDY) renders it a potential candidate for magnetic storage media. This paper delves into the magnetic properties of GDY doped with 5d transition metal (TM) atoms via first-principles calculations. Our results divulge the stable embedding of these TM atoms within the triangular cavities of GDY, yielding a significant magneto-crystal anisotropy energy. In particular, Ta@GDY exhibits a remarkable magneto-crystal anisotropy energy value of 11.72 meV. By introducing TM atoms at the top, one could significantly change the magneto-crystal anisotropy energy value of the system, subsequently flipping the easy magnetization axis. The MAE values of Os-

W

3

@GDY and Re-

I
r

3

@GDY are −21.60 meV and −41.68 meV, which are expanded by a factor of 4 and 6 compared to those before the introduction of the top atom. Furthermore, we observed that the magneto-crystal anisotropy energy value of Ta@GDY is modulated by strain. Our research uncovers GDY as a promising substrate for two-dimensional magnetic materials that could be exploited in forthcoming magnetic memory devices.
A hybrid interferometer sensor for simultaneous measurement of temperature and gas pressure based on tapered seven-core fiber and PDMS
Authors: Huang Huiling , Jiang Chao , Hu Chuanju , Deng Longfeng , Li Li , Gao Jiawei , Shu Yukun 
Published: June 2023

Abstract
A novel hybrid interferometer sensor composed of a tapered seven-core fiber (TSCF) and a polydimethylsiloxane (PDMS) cap at the end face of a TSCF is proposed for simultaneous measurement of temperature and gas pressure. TSCF forms a Michelson interferometer (MI), and the PDMS cap on the end surface of TSCF forms a Fabry–Pérot interferometer (FPI). The sensing head consisted of a cascade of MI and FPI. When the external temperature or gas pressure changes, owing to the thermal effect or elastic deformation of PDMS, the interference spectrum of the FPI shifts significantly, so the FPI is very sensitive to temperature and gas pressure. MI, which is made of quartz optical fiber, is sensitive only to temperature and is not to gas pressure. The experimental results show that FPI has a temperature sensitivity of −0.22 nm °C−1 in the temperature range of 40 °C–80 °C, and a gas pressure sensitivity of −2.27 nm MPa−1 in the gas pressure range of 0–0.3 MPa. MI has a temperature sensitivity of 0.05 nm °C−1 in the temperature range of 40 °C–80 °C, and a gas pressure sensitivity of zero in the gas pressure range of 0–0.3 MPa. Using the temperature and gas pressure sensitivities of FPI and MI to construct a measurement matrix, it is possible to simultaneously measure temperature and gas pressure, eliminating their cross-sensitivity. This sensor has the comprehensive advantages of compact structure, small size, easy manufacturing, low cost, high reliability, and high sensitivity, and is expected to be applied in industrial practice.
Automatic exposure control method for 3D shape measurement of specular surface based on digital fringe projection
Authors: Feng Luyuan , Kang Jiehu , Li Hongtong , Zhang Zhen , Sun Zefeng , Wu Bin 
Published: June 2023

Abstract
Digital fringe projection (DFP) is widely applied in three-dimensional (3D) shape measurements. However, its performance is severely disturbed while measuring complex surfaces with an extensive range of reflectivity. In this paper, to enhance the underexposed regions and reduce the saturated regions, an automatic and effective method is proposed for the multi-exposure determination of the DFP system. During the whole process, only one unsaturated image must be captured preliminarily, which could establish an adaptive strategy based on the intensity value distribution function. Raw absolute phase maps captured with different exposure times are synthesized at the pixel level for phase retrieval and 3D reconstruction. To evaluate the effectiveness of our method, a high dynamic range method and a global optimal exposure method are introduced for comparison. Verification experiments demonstrate that our method performs better for the 3D reconstruction results of complex surfaces with a large reflectivity range.
Variational properties of nonlocal singular problems
Authors: Canino Annamaria , Montoro Luigi , Sciunzi Berardino , Trombetta Alessandro 
Published: June 2023

AbstractWe consider a general class of nonlocal problems involving the fractional Laplacian and singular nonlinearities and we deal with the variational characterization of the solutions. Even though solutions generally have not fractional Sobolev regularity, we provide a variational characterization of the solutions via a suitable action functional.