bluuebunny/crossref_metadata_2025_split huggingface dataset:
Listening to the Sounds of the Algorithm
Authors: Lenglet Marc 
Published: January 2023

Abstract
Phenomenology is both a difficult and sometimes undervalued philosophical tradition. In organization theory, it is often criticized for its supposed inability to get rid of the dualism of subject and object on the one hand, and the conceptual toolbox that goes with this dichotomic understanding of the world on the other. This chapter takes a contrary view and advocates for the need to further develop the phenomenological gaze, building from the example of the social studies of finance. Drawing from a couple of examples focusing on noise in financial markets, I discuss how algorithms have changed the type of sounds that one can experience on the trading floor. I thereafter make a few proposals for prolonging our study of market materiality beyond the traditional recipes of the social studies of finance, thanks to embodied phenomenological descriptions. I highlight the need for making space for the voice-less actors and actants, for redeveloping the perceptual and sensorial dimensions of experience, and for paying attention to moments of dissonance.
Producing the Organizational Space
Authors: Uda Tadashi 
Published: January 2023

Abstract
This study explores how the organizational space of Buddhist temples as co-working spaces in Japan was bodily produced by priests, a small company, and users, drawing on a phenomenological qualitative approach. Whereas phenomenology has attracted scholars’ attention in the literature on organizational space, there is still little research that describes the detailed history and context of space production, and adopts a holistic approach to illuminate the interaction between various aspects, such as organization and society. Moreover, previous studies tend to mainly draw on the literature of the body and embodiment processes in the Western world. Focusing on the case study of ‘tera-co-working’, which brings together traditional Buddhist temples and contemporary co-working spaces, we found that ‘the body seen by others’, based on the non-Western (Japanese) literature, the tatami mat as a foundational artefact, the yukaza as a mode of sitting, and the sacred atmosphere retained by daily religious duties, interact and have significant roles in producing the lived experience of temple co-working spaces.
OsSYMRK Plays an Essential Role in AM Symbiosis in Rice (Oryza sativa)
Authors: Miyata Kana , Hosotani Moe , Akamatsu Akira , Takeda Naoya , Jiang Wendi , Sugiyama Taisei , Takaoka Ryou , Matsumoto Kotarou , Abe Satsuki , Shibuya Naoto , Kaku Hanae 
Published: January 2023

AbstractArbuscular mycorrhizal (AM) fungi establish mutualistic symbiosis with a wide range of terrestrial plants, including rice. However, the mechanisms underlying the initiation of AM symbiosis are yet to be elucidated, particularly in nonleguminous plants. We previously demonstrated that chitin elicitor receptor kinase 1 (OsCERK1), a lysin motif receptor–like kinase essential for chitin-triggered immunity, also plays a key role in AM symbiosis in rice. However, the mechanisms underlying the regulation of switching between immunity and symbiosis by OsCERK1 are yet to be fully elucidated. SYMBIOSIS RECEPTOR–LIKE KINASE (SYMRK)/DOES NOT MAKE INFECTIONS 2 (DMI2) is a leucine-rich repeat receptor–like kinase associated with both root nodule symbiosis and AM symbiosis in legumes. The homolog of SYMRK in rice, OsSYMRK, has a shorter form than that in legumes because OsSYMRK lacks a malectin-like domain (MLD). The MLD reportedly contributes to symbiosis in Lotus japonicus; however, the contribution of OsSYMRK to AM symbiosis in rice remains unclear. Phylogenetic analyses indicated that the MLD of SYMRK/DMI2 is widely conserved even in mosses and ferns but absent in commelinids, including rice. To understand the function of OsSYMRK, we produced an Ossymrk knockout mutant using genome editing technology. AM colonization was mostly abolished in Ossymrk with a more severe phenotype than Oscerk1. Ca2+ spiking against chitin tetramer was also diminished in Ossymrk. In contrast, comparable defense responses against chitin heptamer to the wild type were observed in Ossymrk. Bimolecular fluorescence complementation studies demonstrating an interaction between OsSYMRK and OsCERK1 indicate that OsSYMRK may play an important role in switching from immunity to symbiosis through the interaction with OsCERK1 in rice.
microRNA408 and its encoded peptide regulate sulfur assimilation and arsenic stress response in Arabidopsis
Authors: Kumar Ravi Shankar , Sinha Hiteshwari , Datta Tapasya , Asif Mehar Hasan , Trivedi Prabodh Kumar 
Published: January 2023

Abstract
MicroRNAs (miRNAs) are small non-coding RNAs that play a central role in regulating various developmental and biological processes. The expression of miRNAs is differentially modulated in response to various biotic and abiotic stresses. Recent findings have shown that some pri-miRNAs encode small regulatory peptides known as microRNA-encoded peptides (miPEPs). miPEPs regulate the growth and development of plants by modulating corresponding miRNA expression; however, the role of these peptides under different stress conditions remains unexplored. Here, we report that pri-miR408 encodes a small peptide, miPEP408, that regulates the expression of miR408, its targets, and associated phenotype in Arabidopsis. We also report that miR408, apart from Plantacyanin (ARPN) and Laccase3 (LAC3), targets a glutathione S-transferase (GSTU25) that plays a role in sulfur assimilation and exhibits a range of detoxification activities with the environmental pollutant. Plants overexpressing miR408 showed severe sensitivity under low sulfur (LS), arsenite As(III), and LS + As(III) stress, while miR408 mutants developed using the CRISPR/Cas9 approach showed tolerance. Transgenic lines showed phenotypic alteration and modulation in the expression of genes involved in the sulfur reduction pathway and affect sulfate and glutathione accumulation. Similar to miR408 overexpressing lines, the exogenous application of synthetic miPEP408 and miPEP408OX lines led to sensitivity in plants under LS, As(III), and combined LS + As(III) stress compared to the control. This study suggests the involvement of miR408 and miPEP408 in heavy metal and nutrient deficiency responses through modulation of the sulfur assimilation pathway.
Misdemeanor Prosecution
Authors: Agan Amanda , Doleac Jennifer L , Harvey Anna 
Published: January 2023

Abstract
Communities across the United States are reconsidering the public safety benefits of prosecuting nonviolent misdemeanor offenses, yet there is little empirical evidence to inform policy in this area. We report the first estimates of the causal effects of misdemeanor prosecution on defendants’ subsequent criminal justice involvement. We leverage the as-if random assignment of nonviolent misdemeanor cases to assistant district attorneys (ADAs) who decide whether a case should be prosecuted in the Suffolk County District Attorney’s Office in Massachusetts. These ADAs vary in the average leniency of their prosecution decisions. We find that for the marginal defendant, nonprosecution of a nonviolent misdemeanor offense leads to a 53% reduction in the likelihood of a new criminal complaint and a 60% reduction in the number of new criminal complaints over the next two years. These local average treatment effects are largest for defendants without prior criminal records, suggesting that averting criminal record acquisition is an important mechanism driving our findings. We also present evidence that a recent policy change in Suffolk County imposing a presumption of nonprosecution for nonviolent misdemeanor offenses had similar beneficial effects, decreasing the likelihood of subsequent criminal justice involvement.
Justifying Dissent
Authors: Bursztyn Leonardo , Egorov Georgy , Haaland Ingar , Rao Aakaash , Roth Christopher 
Published: January 2023

Abstract
Dissent plays an important role in any society, but dissenters are often silenced through social sanctions. Beyond their persuasive effects, rationales providing arguments supporting dissenters’ causes can increase the public expression of dissent by providing a “social cover” for voicing otherwise stigmatized positions. Motivated by a simple theoretical framework, we experimentally show that liberals are more willing to post a tweet opposing the movement to defund the police, are seen as less prejudiced, and face lower social sanctions when their tweet implies they had first read credible scientific evidence supporting their position. Analogous experiments with conservatives demonstrate that the same mechanisms facilitate anti-immigrant expression. Our findings highlight both the power of rationales and their limitations in enabling dissent and shed light on phenomena such as social movements, political correctness, propaganda, and antiminority behavior.
Chordin Like-1 Regulates Osteoblast and Adipocyte Differentiation Through Stabilizing Insulin-Like Growth Factor Binding Protein 3
Authors: Sun Haijian , Wang Shuang , Yang Zheng , Tian Lijie , Li Xiaoxia , Zhou Jie , Wang Baoli 
Published: January 2023

Abstract
Chordin like-1 (CHRDL1) is an antagonist of bone morphogenetic proteins (BMPs) that acts through binding BMPs and blocking their interaction with BMP receptors. CHRDL1 plays a role in osteoblast differentiation but controversial effects were reported. On the other hand, the role of CHRDL1 in adipogenesis is unknown. In the present study, we investigated the function of CHRDL1 in regulating differentiation of osteoblasts and adipocytes and elucidated the underlying mechanism. CHRDL1 expression was downregulated during osteogenesis while it was upregulated during adipogenesis in primary cultured and established mesenchymal progenitor cell lines. Functional experiments revealed that CHRDL1 suppressed osteoblast differentiation and promoted adipocyte differentiation. Mechanistic explorations revealed that CHRDL1 is directly bound to insulin-like growth factor binding protein 3 (IGFBP3) and attenuated the degradation of the latter. Furthermore, CHRDL1 and IGFBP3 suppressed the activity of insulin receptor substrate 1 (IRS1)/AKT serine/threonine kinase (AKT)/mechanistic target of rapamycin kinase complex 1 (mTORC1) signaling in progenitor cells undergoing osteogenic differentiation. By contrast, they activated AKT/mTORC1 signaling independently of IRS1 during adipogenic differentiation. CHRDL1 enhanced the interaction of nuclear IGFBP3 and retinoid X receptor α (RXRα) during adipogenesis, and inhibition of RXR inactivated AKT and attenuated the stimulation of adipogenic differentiation by CHRDL1. Overexpression of IGFBP3 relieved the perturbation of osteogenic and adipogenic differentiation of progenitor cells induced by CHRDL1 silencing. Finally, CHRDL1 and IGFBP3 were upregulated in the trabecular bone of aged mice. Our study provides evidence that CHRDL1 reciprocally regulates osteoblast and adipocyte differentiation through stabilizing IGFBP3 and differentially modulating AKT/mTORC1 signaling.
Utilization of Transport Data to Decrease Unnecessarily Repeated Laboratory Tests
Authors: Adair Austin Brett , Dejanovich Bryan , Walsh Michele 
Published: January 2023

Objectives
In pediatric patients being transported for management of diabetic ketoacidosis, laboratory tests will frequently be trended throughout transportation and subsequently immediately repeated upon arrival to a particular institution. These laboratory tests may not add value to a patient’s care trajectory and therefore may be unnecessary. This study examines differences between pH, sodium, potassium, chloride, bicarbonate, and glucose levels drawn during transportation and those drawn at our home institution immediately upon arrival to determine if repeating those laboratory tests upon arrival to the emergency department serves any purpose in adding to patient care.

Methods
This study compares pH, sodium, potassium, chloride, bicarbonate, and glucose levels drawn during transport and at our home institution. Box and whisker plots between transport and institution laboratory values were constructed. A Wilcoxon signed rank test was performed to determine differences between pH, sodium, potassium, bicarbonate, and glucose levels, as these value sets were not normally distributed. A paired t test was performed to determine differences between transport and institution chloride values given that these value sets were normally distributed. Savings were then calculated based on charges to the patient to determine overall cost savings by not immediately repeating these laboratory tests upon presentation.

Results
Box and whisker plots showed marked similarity between laboratory tests drawn in transport and those immediately upon arrival to our ED. Paired t test did not demonstrate a statistical difference between transport and ED chloride levels (P = 0.5699); therefore, we failed to reject the null hypothesis. Wilcoxon signed rank test did not demonstrate a statistical difference between transport and ED pH (P = 0.1294) and potassium (P = 0.4523) values; therefore, we failed to reject the null hypothesis. However, Wilcoxon signed rank test did demonstrate a statistically significant difference between uncorrected sodium (P = 0.0006), corrected sodium (P = 0.0075), bicarbonate (P = <0.0001), and glucose levels (P = 0.0086).

Conclusions
Although there were some statistically significant differences between the laboratory value sets, it is arguable whether there are any clinically significant differences between them.
Based on our failure to show a clinically significant difference between laboratory values drawn during transportation and those drawn immediately upon presentation to the institution, repeating laboratory draws after transportation do not add value to a patient’s care trajectory. We should therefore rely on the laboratory values that were drawn from our transportation teams as part of the continuum of patient care.
Sandaracinobacteroides sayramensis sp. nov., a yellow-pigmented bacterium isolated from lake water
Authors: Xamxidin Maripat , Ou Xin-Yi , Huang Xin-Peng , Abliz Abduwali , Wang Tao , Chen Can , Wu Min 
Published: January 2023

A Gram-negative, non-motile, facultatively anaerobic, rod-shaped bacterium, designated strain RS1-74T, was isolated from the surface water of Sayram Lake, Xinjiang Uygur Autonomous Region, China. The strain was able to grow optimally at 30 °C and pH 7.0–7.5, and in the presence of 0–0.5 % (v/w) NaCl. Catalase and oxidase activities were present. H2S was produced. Chemotaxonomic analysis showed Q-10 was the sole respiratory quinone. The polar lipids were composed of phosphatidylethanolamine, diphosphatidylglycerol, two glycolipids, phosphatidylglycerol, sphingoglycolipid and two unidentified lipids. Summed feature 3 (C16 : 1
ω7c and/or C16 : 1
ω6c) and summed feature 8 (C18 : 1
ω7c and/or C18 : 1
ω6c) were the predominant fatty acids. Phylogenetic analysis based on 16S rRNA gene sequence showed that strain RS1-74T was closely related to ‘

Sandaracinobacter neustonicus

’ JCM 30 734 (98.65 %), ‘

Sandaracinobacter sibiricus

’ RB16-17 (98.42 %) and

Sandaracinobacteroides hominis

SZY PN-1T (97.09%). The genomic DNA G+C content was 66.45 mol%. The average nucleotide identity and DNA–DNA hybridization values among the genomes of strain RS1-74T and ‘

Sandaracinobacter neustonicus

’ JCM 30734 and

Sandaracinobacteroides hominis

SZY PN-1T were 78.2 and 77.22 %, and 22.2 and 20.40 %, respectively. Based on the physiological, biochemical, phylogenetic and genomic data, strain RS1-74T represents a novel species within the genus

Sandaracinobacteroides

, for which the name Sandaracinobacteroides sayramensis sp. nov. is proposed, with type strain RS1-74T (=KCTC 82674T=MCCC 1K06282T).
Use of multimodal sensory cues in predator avoidance by wild-caught zebrafish shoals
Authors: Mukherjee Ishani , Malakar Aniket , Das Dipjyoti , Bhat Anuradha 
Published: January 2023

AbstractShoaling in fishes is regulated by factors like predation, vegetation cover, water flow and food availability. Shoals detect and respond to changes in these ecological factors using a multimodal sensory system. Here, we examine the immediate response of wild-caught zebrafish (Danio rerio)shoals to cues from its natural predator, the snakehead (Channa sp.). Zebrafish shoals were recorded upon exposure to (1) olfactory predator cues, (2) visual predator cues, (3) both cues together, and (4) no cue. We tracked individuals and analysed shoal responses across these treatments. We found that compared to control treatments, shoals receiving either visual or olfactory cues had significantly greater: (i) cohesion, (ii) polarization and (iii) velocity. Interestingly, when the shoals received both cues simultaneously, the cohesion, polarization and velocity decreased and a significantly greater number of individual freezing events occurred. Therefore, zebrafish relied on both visual and olfactory cues to escape predation. However, when shoals were presented with both cues together, while freezing frequency increased, other responses were comparable to control treatments where no predator cue was provided. While this study indicates that multimodal cues elicit a different anti-predator response than the cues singly, more experiments are required to identify the underlying cause of this behaviour.
Documentation and prevalence of prenatal and neonatal outcomes in a cohort of individuals with KBG syndrome
Authors: Kierzkowska Ola , Sarino Kathleen , Carter Drake , Marchi Elaine , Voronova Anastassia , Lyon Gholson J. 
Published: January 2023

AbstractMutations in the Ankyrin Repeat Domain 11 (ANKRD11) gene are associated with KBG syndrome, a developmental disability that affects multiple organ systems and presents with a variety of skeletal, cardiac, gastrointestinal, and neuropsychiatric manifestations. The function ofANKRD11in human growth and development is not well understood, but its importance is established by the fact that constitutive or conditional gene knockout or mutation are lethal in mice embryos and/or pups. In addition, it plays a vital role in chromatin regulation, transcription, and development. Individuals with KBG syndrome are often misdiagnosed or undiagnosed until later in life, due to a combination of varying phenotypes, lack of targeted prenatal screening, and lack of documentation of prenatal and neonatal symptoms. The present study aims to report perinatal outcomes in individuals with KBG syndrome and their families and compare them to the prevalence in the overall population. We obtained data from 42 individuals through videoconferences, notes, and emails. Our results show that 45.2% of our cohort was born by C-section, 33.3% had a congenital heart defect, 23.8% were born before 37-weeks ‘ gestation, 23.8% were admitted to the NICU, 14.3% were small for gestational age, and 14.3% of the families in our cohort had a history of miscarriage. The prevalence of birth by C-section, premature birth, NICU admission, and small for gestational age was higher in our cohort compared to the overall population, including non-Hispanic and Hispanic populations. Other reports included feeding difficulties (21.4%), neonatal jaundice (14.3%), decreased fetal movement (7.14%), and pleural effusionsin utero(4.67%). These findings suggest that there may be an association betweenANKRD11variants or microdeletions and perinatal complications, and further research is needed to better assess the mechanisms behind this relationship. Comprehensive perinatal studies about KBG syndrome and updated documentation of its phenotypes can facilitate earlier detection, diagnosis, and treatment.
Evaluation of Potential Adverse Events Following COVID-19 mRNA Vaccination Among Adults Aged 65 Years and Older: A Self-Controlled Study in the U.S
Authors: Shoaibi Azadeh , Lloyd Patricia C. , Wong Hui-Lee , Clarke Tainya C. , Chillarige Yoganand , Do Rose , Hu Mao , Jiao Yixin , Kwist Andrew , Lindaas Arnstein , McEvoy Rowan , Ondari Michelle , Parulekar Shruti , Shi Xiangyu , Wang Jing , Lu Yun , Obidi Joyce , Zhou Cindy K. , Kelman Jeffrey A. , Forshee Richard A. , Anderson Steven A. 
Published: January 2023

ABSTRACTBackgroundOur near-real-time safety monitoring of 16 adverse events (AEs) following COVID-19 mRNA vaccination identified potential elevations in risk for six AEs following primary series and monovalent booster dose administration. The crude association with AEs does not imply causality. Accordingly, we conducted robust evaluations of the potential associations.MethodsWe conducted self-controlled case series studies of COVID-19 mRNA vaccines (BNT162b2 and mRNA-1273) in U.S. Medicare beneficiaries aged 65 years and older. Adjusted incidence rate ratio (IRRs) and 95% confidence intervals (CIs) were estimated following primary series doses for acute myocardial infarction (AMI), pulmonary embolism (PE), immune thrombocytopenia (ITP), disseminated intravascular coagulation (DIC); and following booster doses for AMI, PE, ITP, Bell ‘s Palsy (BP) and Myocarditis/Pericarditis (Myo/Peri).ResultsAmong 3,360,981 individuals who received 6,388,542 primary series doses and 6,156,100 individuals with monovalent booster doses of either BNT162b2 or mRNA-1273, AE counts were: AMI (3,653 primary series, 16,042 booster), inpatient PE (2,470 primary, 5,085 booster), ITP (1,085 primary, 88 booster), DIC (254 primary), BP (3,268 booster), and Myo/Peri (1,295 booster). The IRR for inpatient PE cases following BNT162b2 primary series and booster was 1.19 (95% CI: 1.03 to 1.38) and 0.86 (95% CI: 0.78 to 0.95), respectively; and for mRNA-1273 primary series and booster, 1.15 (95% CI: 0.94 to 1.41) and 0.87 (95% CI: 0.79 to 0.96), respectively. The IRR for BP following BNT162b2 and mRNA-1273 booster was 1.17 (95% CI: 1.06 to 1.29) and 1.16 (95% CI: 1.05 to 1.29), respectively.ConclusionIn these two studies of the U.S. elderly we did not find an increased risk for AMI, ITP, DIC, and Myo/Peri; the results were not consistent for PE; and there was a small elevated risk of BP after exposure to COVID-19 mRNA vaccines. These results support the favorable safety profile of COVID-19 mRNA vaccines administered in the elderly.HIGHLIGHTSThere was no increased risk for four of six outcomes following COVID-19 monovalent mRNA vaccines. There was a small elevated risk of Bell ‘s Palsy after exposure to COVID-19 monovalent mRNA vaccines. Risk of pulmonary embolism was not consistent after exposure to COVID-19 monovalent mRNA vaccines.