bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transportation-related Environmental Mixtures and Diabetes Prevalence and Control in Urban/Metropolitan Counties in the United States
Authors: Weiss Margaret C , Adusumilli Sneha , Jagai Jyotsna S , Sargis Robert M 
Published: May 2023

Abstract
Diabetes rates in the United States are staggering and climbing. Importantly, traditional risk factors fail to completely account for the magnitude of the diabetes epidemic. Environmental exposures, including urban and metropolitan transportation quality, are implicated as contributors to disease. Using data from the county-level Environmental Quality Index (EQI) developed for the United States, we analyzed associations between transportation and air quality environmental metrics with overall diabetes prevalence and control within urban/metropolitan counties in the United States from 2006 to 2012. Additionally, we examined effect modification by race/ethnicity through stratification based on the county-level proportion of minority residents. Last, we applied mixture methods to evaluate the effect of simultaneous poor transportation factors and worse air quality on the same outcomes. We found that increased county-level particulate matter air pollution and nitrogen dioxide along with reduced public transportation usage and lower walkability were all associated with increased diabetes prevalence. The minority proportion of the population influences some of these relationships as some of the effects of air pollution and the transportation-related environment are worse among counties with more minority residents. Furthermore, the transportation and air quality mixtures were found to be associated with increased diabetes prevalence and reduced diabetes control. These data further support the burgeoning evidence that poor environments amplify diabetes risk. Future cohort studies should explore the utility of environmental policies and urban planning as tools for improving metabolic health.
Genetic and Environmental Effects on the Early Motor Development as a Function of Parental Educational Attainment
Authors: Zi Yahua , van Beijsterveldt Catharina E. M. , Bartels Meike , de Geus Eco J. C. 
Published: May 2023

ABSTRACT

Introduction
The contribution of genetic and environmental factors to individual differences in early motor development are still largely uncharted. This large-scale twin study establishes the genetic and environmental influences on the timing of motor milestones achievement, it further tests whether the influences are moderated by parental education.

Methods
The twins came from families registered in the Netherlands Twin Register (NTR) from 1986 to 2016. In 22148 complete twin pairs, mother-reported ages at which each twin was able to first-time roll from back to belly, sit unassisted, hands-and-knees crawl, stand up unaided, and walk independently were used to extract an early motor development factor (MD-FS). Parental education was dichotomized (“both parents with low/average education” versus “at least one parent with high education” with university degree as a threshold).

Results
Additive genetics explained 52% of the variance in motor development, the remaining 39% and 9% were explained by shared and non-shared environment separately. Mean age of achieving motor milestones tended to be higher in infants with high-educated parents, and a moderation of parental education on the genetic and environmental variance in motor development was seen in female twins with larger heritability in the high-educated parents group (64% versus 43%) paired to a lower shared environmental influence (28% versus 48%). Only 7-8% of the variance was accounted for non-shared environmental factors, including measurement error. The pattern of results did not change when the degree of urbanicity, a correlate of parental education, was additionally considered.

Conclusions
Genetic factors explain most of the individual differences in the timing of motor milestone achievement, but factors related to the shared home environment also play an important role in early motor development.
Identification of vulnerable carotid plaque with histologically validated CT-derived plaque maps
Authors: Obaid Daniel Rhys , Okonji Ike , Cheng Suk F , Giannopoulos Argyrios A , Kamalathevan Pragash , Halcox Julian , Rodriguez-Justo Manuel , Richards Toby 
Published: May 2023

Objectives: Ruptured carotid plaque causes stroke, but differentiating rupture-prone necrotic core from fibrous tissue with CT is limited by overlap of X-ray attenuation. We investigated the ability of CT-derived plaque maps created from ratios of plaque/contrast attenuation to identify histologically proven vulnerable plaques. Methods: Seventy patients underwent carotid CT angiography and carotid endarterectomy. A derivation cohort of 20 patients had CT images matched with histology and carotid plaque components attenuation defined. In a validation cohort of 50 patients, CT-derived plaque maps were compared in 43 symptomatic vs 40 asymptomatic carotid plaques and accuracy detecting vulnerable plaques calculated. Results: In 250 plaque areas co-registered with histology, the median attenuation (HU) of necrotic core 43(26-63), fibrous plaque 127(110-162) and calcified plaque 964 (816–1207) created significantly different ratios of plaque/contrast attenuation. CT-derived plaque maps revealed symptomatic plaques had larger necrotic core than asymptomatic (13.5%(5.9–33.3) vs 7.4%(2.3–14.3), p = 0.004) with large necrotic core predicting symptoms (area under ROC curve 0.68, p = 0.004). Twenty-four of 47 carotid plaques were histologically classified as most vulnerable (Starry-Type VI). Plaque maps revealed Type VI plaques had a greater necrotic core volume than Type IV/V plaques and a necrotic core/fibrous plaque ratio >0.5 distinguished Type VI plaques with sensitivity 75.0% (55.1–88.0) and specificity of 39.1% (22.2–59.2). Conclusions: Carotid plaque components can be differentiated by CT using a ratio of plaque/contrast attenuation. CT-derived plaque map volumes of necrotic core help distinguished the most vulnerable plaques. Advances in knowledge: CT-derived plaque maps based on plaque/contrast attenuation may provide new markers of carotid plaque vulnerability.
Comparative evaluation of serum interleukin 6 with neutrophil - lymphocyte and platelet -lymphocyte ratio in pre and post-surgery oral squamous cell carcinoma.
Authors: Bhargava Pragati , Bhowate Rahul 
Published: May 2023

Background:Oral Squamous Cell Carcinoma is a major health burden in Asian countries necessitating the need for active research in terms of diagnosis and management. Various pro-inflammatory markers such as Interleukins, TNF Alpha, Interferon gamma and inflammatory mediators such as Neutrophils, lymphocytes, monocytes and mast cells are known to be involved in the tumor associated inflammatory status.Aim:To explore the role of Interleukin - 6, Neutrophil to Lymphocyte ratio and Platelet to lymphocyte ratio in Oral Squamous Cell Carcinoma in both pre and post operative conditions. Materials and Methods: Forty subjects who were Clinically and Histo-pathologically diagnosed, graded and staged based on TNM staging of OSCC included in the study. Pre and Post operative assessment of serum Interleukin-6, Neutrophil to Lymphocyte Ratio and Platelet Lymphocyte Ratio was carried out.Results:On evaluation significant difference was evident on comparison between the preoperative IL-6 levels and post operative levels. On evaluation of NLR, there was also a significant difference in preoperative NLR based on the staging of the tumor, the mean preoperative NLR higher in stage Iva than in stage III. On evaluation of PLR, the mean preoperative PLR differed significantly between stage III and stage IV a OSCC. However, no evaluative difference was noted in pre and post operative PLR based on the histopathological type of OSCC. But, there was a significant difference noted in the PLR levels between the pre and the post operative status.Conclusion:NLR and PLR are useful markers representing the stage of the tumor as higher values of NLR and PLR are associated with high stages of tumor. Pre and Post operative IL-6 and PLR can also be useful in post operative and post treatment inflammatory status in individuals affected with Oral Squamous Cell Carcinoma.
Hypertension and COVID-19 fractional derivative model with double dose vaccination
Authors: Okyere Samuel , Ackora-Prah Joseph , Bonyah Ebenezer , Barnes Bennedict , Boateng Maxwell Akwasi , Takyi Ishmael , Adarkwa Samuel Akwasi 
Published: May 2023

The prevalence of at least one underlying medical condition, which increases the likelihood of developing the severe COVID-19 disease, is found in 22 of the world's population. The primary underlying medical condition that contributes to COVID-19 problems in Ghana is hypertension. This work investigate COVID-19 in a population with hypertension taking into account double dose vaccination of susceptible individuals. The study modifies a previous model proposed in the literature to include double dose vaccination and Atangana-Baleanu-Caputo fractional derivatives is used to solve the model. We give few definitions of the ABC operator and determine the existence and uniqueness of the solution. Using COVID-19 data for the period February 21, 2021 to July, 24 2021, the model is tested. The dynamics of the disease in the community were shown to be influenced by fractional-order derivatives. Contrary to the previous model proposed in the literature, the vulnerable group saw a significant reduction in the number, which may be attributed to the double dose vaccination. We recommend a cost-effective optimal control analysis in future work.
Predictive factors of large liver cell carcinoma tumor response after first conventional transarterial chemoembolization in Indonesia according to the modified response evaluation in solid tumors criteria: a preliminary study
Authors: Matondang Sahat Basana Romanti Ezer , Lios Liem Arinuryanto , Hilmy Ibrahim Abubakar , Hasan Irsan , Prihartono Joedo 
Published: May 2023

Background: Various factors affect the response of large hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE), and the high demand for TACE procedures highlights the need for information and methods on the criteria for patient selection. Methods: Thirty-six HCC patients who were treated with conventional TACE between January 2014 and January 2020 and had pre- and postoperative imaging data were included in the analysis. The patients were categorized as tumor responders (complete or partial response) or nonresponders (stable or progressive disease) according to the modified response evaluation criteria in solid tumors (mRECIST). Eight predictive factors (Tumor diameter, Tumor amount, tumor vascularity, portal vein invasion, tumor location, presence of tumor capsule, Child–Pugh class, and alpha-fetoprotein (AFP) level) of tumor response were evaluated using multivariate analysis with logistic regression. Results: Only 42% of patients fell into the category of responders after conventional TACE. None of the Child–Pugh class B patients showed a tumor response. A multivariate analysis of the Child–Pugh class A patient group showed that a lesion diameter of 5–10 cm (OR: 8.78, 95% CI: 1.73–44.55; P = 0.009) are an independent predictor of tumor response after the first TACE procedure. Conclusions: A tumor diameter of 5–10 cm could be use as a predictor of tumor response after the first conventional TACE in Child–Pugh A patients, further researches are needed to confirm this finding.
Cross-cultural adaptation and validation of the Greek version of the Kerlan-Jobe orthopaedic clinic shoulder and elbow score in Greek overhead athletes
Authors: Paraskevopoulos Eleftherios , Plakoutsis George , Papandreou Maria 
Published: May 2023

Background: Overhead athletes frequently perform rapid and powerful throwing overhead strokes in positions at the extreme range of motion, increasing the risk of upper limb injury. The Kerlan-Jobe Orthopedic Clinic (KJOC) Shoulder and Elbow Score has shown to be a valid and reliable questionnaire that can be used for the assessment of the functional status of the upper limb of patients involved in highly demanding overhead sports. The KJOC has been translated into several other languages however, a Greek version of the KJOC is not available yet. Methods: The KJOC will be cross-culturally adapted into Greek following international guidelines. At least 100 overhead athletes with or without shoulder or elbow complaints will be recruited and asked to fill in the Greek version of the KJOC twice and the Disabilities of Arm, Shoulder and Hand Questionnaire (DASH) once. The internal consistency and the test-retest reliability will be examined using Cronbach’s alpha and the intraclass correlation coefficient (ICC), respectively. The standard error of measurement (SEM) and the minimum detectable change (MDC) will be calculated and possible ground or ceiling effects will be also examined. Convergent validity will be evaluated with the Greek DASH using Pearson’s correlation. Results: The results of this study will be presented in an article to be published later. Conclusions: This report describes the process of translation and cross cultural adaptation of the Greek version of the KJOC. We believe a study protocol will assist researchers in the field to improve the reporting of similar studies and as a result improve the quality of their studies.
The signifying culture: An intercultural and qualitative analysis of Tiv and Yoruba folktales for moral instruction and character determination in children
Authors: Olugbemi-Gabriel Olumide , Ukpi Mbasughun 
Published: May 2023

Background: In the study of African communities, folktales have remained a constant element. With their origin in the culture of oral storytelling, folktales have often been used by older age groups to guide and mould behavioural patterns in children. In ancient and traditional African societies, children were gathered at the end of the day by older members of the community for tales by moonlight sessions aimed at guiding their moral decisions. With globalisation and its consequent effects such as migration, dislocation and disindigenisation, the culture of communal folktale sessions is experiencing a quick death. This paper engages with the relevance of folktales as moral guides for children in African societies and as a renewed path to increased societal stability facilitated by morally set individuals. Methods: The folktales were randomly selected from a pool of Tiv and Yoruba folktales in Nigeria. Two animal-based folktales which are part of shared folk culture were picked from the Tiv society and one from the Yoruba society. The study follows a narrative and content analysis approach where the selected folktales are corroborated by four key informants, two males and two females within the ages of 50-65. Results: With particular focus on the benefits of promoting and re-introducing the folktale culture to encourage positive behavioural traits amongst individuals in the society, the study primarily highlights folktales as reflective of human life. In identifying this similarity, the character of children is largely influenced by the moral values inherent in these folktales. Conclusions: There needs to be an increased use of media and audio-visual tools to expand the knowledge and accessibility of indigenous African folktales in order to preserve ethnic, national and social identity as well as to provide a moral compass for children.
Teaching without boundaries: interviews exploring the adaptation of collaborative inquiry to the American context
Authors: Carr Olivia G. , Cravens Xiu 
Published: May 2023

Purpose: This study qualitatively examines the efforts of implementing teacher-led collaborative inquiry in American public schools to improve instruction. We focus on a model called Teacher Peer Excellence Group (TPEG), designed to capture the essence of Japanese lesson study and Chinese teaching-study groups that involve lesson planning, peer observations, feedback, and revision. Methods: We conduct qualitative case studies in three pilot schools using a constructivist research paradigm. Findings: We identify action steps essential to introducing and sustaining the TPEG model and pathways to local adaptation. Implications for research and practice: The study contributes to the body of research that seeks to understand the role of instructional leadership and teacher decision-making in successful school-level initiatives.
Co-occurrence of behavioural risk factors for non-communicable diseases among 40-year and above aged community members in three regions of Myanmar
Authors: Mon Aye Sandar , Win Hla Hla , Sandar Win Pa , Walton Poppy , Swe Khin Hnin , Vervoort Johanna P. M. , Landsman Jeanet A. , Rusnak Martin , Koot Jaap A. R. 
Published: May 2023

Background: Risky behaviours such as smoking, alcohol consumption, physical inactivity and inadequate consumption of fruits and vegetables are known contributing factors for non-communicable diseases (NCDs) which account for 74% of global mortality. Such behavioural risk factors co-occur frequently resulting in synergistic action for developing NCD related morbidity and mortality. This study aims to assess the existence of multiple risk behaviours and determine the socio-economic and demographic factors associated with co-occurrence of behavioural risks among Myanmar adult population. Method: Data were collected, in the context of the SUNI-SEA project (Scaling Up NCD interventions in Southeast Asia), from 660 community members aged 40 years and above of both sexes, residing in selected urban and rural areas from Ayeyawaddy, Yangon and Mandalay regions of Myanmar. The co-occurrence of behavioural risk factors was presented as percentage with 95% CI and its determinants were identified by multinomial logistic regression. Results: The co-occurrence of two risk behaviours and three or four risk behaviours were found in 40% (95% CI: 36.2%, 43.9%) and 10.8% (95% CI: 8.5%, 13.4%) respectively. Urban residents, men, participants without formal schooling and unemployed persons were more likely to exhibit co-occurrence of two risk behaviors and three or four risk behaviours. Conclusion: The current study shows high prevalence of co-occurrence of behavioural risk factors among Myanmar adults in the study area. NCD prevention and control programs emphasizing management of behavioural risks should be intensively promoted, particularly directed towards multiple behavioural risk factors, and not focused on individual factors only.
METHODOLOGICAL FOUNDATIONS FOR BUILDING AN INCIDENT MANAGEMENT SYSTEM OF A MANAGEMENT COMPANY IN A MARKET ECONOMY
Authors: Gajkova Luybov V. , Izotov Oleg E. 
Published: May 2023

Рассматривается управление жилой недвижимостью и прилегающей территории на основе системы управления инцидентами управляющей компании, как одного из способов регулирования функций эксплуатации, технического и санитарного содержания многоквартирных домов в условиях рыночной экономики.
The management of residential real estate and adjacent territory on the basis of the incident management system of the management company as one of the ways to regulate the functions of operation, technical and sanitary maintenance of apartment buildings in a market economy is considered.
Purpose: to identify the problems that determine the process of working with consumer appeals to the management company, in order to work out the methodological foundations for building an incident management system in the management company.Methodology: the dialectical method is used as a general scientific method of cognition; techniques and tools of system, comparative analysis and generalization.
Results: analyzed the business process, identified business problems relating to the current process of working with customer complaints to the management company, built a strategic map of the management company.
Scope of results: heads of management companies when addressing issues of determining the optimal relationship with consumers to reduce the risk of poor-quality work.
PROBLEMS AND WAYS OF USING CRYPTOCURRENCIES IN THE RUSSIAN FEDERATION
Authors: Verdikhanov Feitulla N. , Morozevich Milaslava I. , Tagirova Aset V. 
Published: May 2023

В данной статье рассмотрена проблема восприятия нового вида электронных денег – криптовалют, а также неправильная трактовка цифровых финансовых активов, изучаются основные проблемы и возможность использования нового вида финансового актива. Цель работы заключается в изучении основных проблем и способов использования криптовалюты в национальной экономике. Рассмотрены виды криптовалют, отличительные особенности и структура популярных криптовалют. Рассмотрена проблема восприятия нового вида электронных денег, изучаются основные проблемы и возможность использования нового вида финансового актива. Подробно описаны способы использования криптовалют. Сопоставлены централизованные и децентрализованные формы электронных цифровых активов. Представлен опыт компаний, которые начали внедрять в свои бизнес-процессы блокчейн и криптовалюты, а также активный переход к цифровым финансовым активам.
Цель: изучить основные проблемы и способы использования криптовалюты в национальной экономике и сформулировать рекомендации по их перспективному применению.
Метод исследования: метод анализа и синтеза, метод обобщения, табличный метод.
Результаты: в работе описано современное состояние использование криптовалют и иных крипотинструментов в мировой и российской экономике и дан обзор основных проблем, с которыми связано их применение. Описаны причины возникновения этих проблем.
Область применения результатов: полученные результаты могут быть использованы для дальнейшего теоретического обоснования природы криптовалют как инновационного экономического инструмента. Кроме того, они могут быть полезны для государств, бизнеса и частных лиц с точки зрения выбора оптимальной модели использования криптовалют в хозяйственной деятельности.