bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of Fibroblast Activation Protein Expression and Incidence of Epithelial Ovarian Cancer Recurrence
Authors: Siregar Effinia Kamila Hanum , Rivany Riza , Harahap Muhammad Rusda , Effendi Iman Helmi , Aldiansyah Dudy , Simanjuntak Roy Yustin , Ardiansyah Edy 
Published: December 2022

Background : Ovarian cancer is one of women death causes and almost diagnosed at advanced stage which related to high recurrence rate therefore accurate biomarker is needed to predict recurrence rate.
Aim: This research purpose to determine correlation of fibroblast activation protein (FAP) expression and epithelial ovarian cancer recurrence at H. Adam Malik Hospital Medan.
Methods: This research is an analytic observational study with case control approach that will be carried out starting in May 2022 until number of samples is met. Immunohistochemical assessment for FAP expression uses Allred score because this system is simplest and has good sensitivity and specificity. The preparations were interpreted by two anatomical pathologists. The correlation between variables was carried out by chi square statistical test with 95% confidence interval and p < 0.05 was considered significant.
Results: The analysis results using Chi Square test showed that there was a significant relationship between tissue FAP expression and ovarian cancer recurrence (p = 0.004). The OR value obtained was 7.429 (95% CI = 1.778 – 31.040), which means patients with tissue FAP expression (+) had risk of recurrent ovarian cancer 7.429 times greater than patients with tissue FAP expression (-).
Conclusion : There is a statistically significant correlation between FAP expression and epithelial ovarian cancer recurrence.
Automated video game parameter tuning with XVGDL+
Authors: Ruiz Quiñones Jorge , Fernández Leiva Antonio J. 
Published: December 2022

Usually, human participation is required in order to provide feedback during the game tuning or balancing process. Moreover, this is commonly an iterative process in which play-testing is required as well as human interaction for gathering all important information to improve and tune the game components&rsquo; specification. In this paper, a mechanism is proposed to accelerate this process and reduce significantly the costs of it, contributing with a solution to perform the game parameter tuning and game balancing using search algorithms and artificial intelligence (AI) techniques. The process is executed in a fully automated way, and just requires a game specification written in a particular video game description language. Automated play-testing, and game&rsquo;s feedback information analysis, are related to perform game parameters&rsquo; tuning and balancing, leading to offer a solution for the problem of optimizing a video game specification. Recently, XVGDL, a new language for specifying video games which is based on the eXtensible Markup Language (XML), has been presented. This paper uses XVGDL+, an extension of this lan- guage that incorporates new components to specify, within the video game specification, desirable goals or requirements to be evaluated after each game execution. A prototypical implementation of a Game Engine (termed XGE+) was also presented. This game engine not only enables the execution of an XVGDL+ game specification but also provides feedback information once the game has finished.
The paper demonstrates that the combination of XVGDL+ with XGE+&nbsp;offers a powerful mechanism for helping solving game AI research problems, in this case, the game tuning of video game parameters, with respect to initial optimization goals. These goals, as one of the particularities of the proposal presented here, are included within the game specification, minimizing the input of the process.
As a practical proof of it, two experiments have been conducted to optimize a game specification written in XVGDL via a hill climbing local search method, in a fully automated way.
Coupler sociologie et alimentation préventive pour une éducation à l’alimentation holistique
Authors: Lebredonchel Louis , Fardet Anthony 
Published: December 2022

L’alimentation représente un enjeu majeur face à la croissante prévalence des maladies chroniques : soit en y contribuant, soit en les prévenant. Une éducation à l’alimentation pourrait permettre de lutter contre celles-ci, ainsi que contre les inégalités sociales de santé qui leurs sont liées. Bien qu’elle soit envisagée depuis une dizaine d’années par différents acteurs en France, l’éducation à l’alimentation semble n’en être qu’à ses débuts. Après avoir synthétisé ses enjeux et ses avancées, nous tenterons de contribuer à sa progression. A partir de réflexions théoriques et d’un travail empirique conduit dans cinq écoles primaires, nous proposons une approche pédagogique consistant en une « éducation à l’alimentation holistique ». Elle encourage les enfants à s’engager personnellement dans une réflexion et compréhension des liens entre l’alimentation, la santé et l’environnement, en y participant davantage en tant que véritables acteurs et qu'en tant que spectateurs passifs.
A review of David Colander, The Making of a European Economist, Cheltenham, UK, Edward Elgar, 2009, 190 pp.
Authors: Nicolae Mariana 
Published: December 2022

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David Colander's book on The Making of a European Economist is somehow a natural continuation of his by now classic studies on economics education in the US and of his book The Making of an Economist, Redux [1]. The book is fascinating to read not only by someone like me who is not really an economist, but has been close to the field and has been teaching students of economics for a long time, but mainly by policy makers both in the field of higher education and in other fields like business where the larger aspects of societal changes are more and more apparent.
Commentary on black political economy
Authors: Haynes Curtis 
Published: December 2022

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The task of this essay is to introduce a comprehensible study of the economic condition of a black sub-altern population in the United States. The framework is informed by the monumental contribution to the field of political economy as developed by Lloyd Hogan in his 1984, Principles of Black Political Economy. Specifically, Hogan presents political economy as: "The study of a human population under going the act of social reproduction, over a protracted period of time, under a set of rules promulgated and enforced by a political state, within a bounded geographical domain." (Hogan, p.12)
THE WESTERN MAKSURAH OF THE GREAT MOSQUE OF DİYARBAKIR, RESEARCH AND EXCAVATION
Authors: HALİFEOĞLU Fatma Meral , ASSENAT Martine 
Published: December 2022

Diyarbakır Great Mosque is a community building located in the district of Cami-i Kebir in the northwest of the traditional city area surrounded by walls. The building on Gazi Street opposite Hasan Pasha Han is inside the road, and the eastern entrance overlooks a square which very likely corresponds to the old forum of the city of Amida. Surrounded by the streets to the North and West, the South overlooks the traditional Sipahi Bazaar. Around the full court near the square of the building, in the south there are: Hanafis section, Shafis section, northern vestibule, Mesudiye Madrasa and its southern portico, a traditional house, and a lavatory. To the east, there is a library, which used to be apparently a timing room (muvakkithane) and an entrance to the East (Eastern Maksurah). To the west, in the Western portico (Western Maksurah), that also includes the Western entrance, there is a Qur'anic school. The octagonal and pointed pyramidal coned fountain, built during the Ottoman period, and the prayer hall and pool, which were raised with several steps, form the other units in the spacious courtyard. In the north of the courtyard, we can find the portico of Mesudiye Madrasa. There is also a solar clock in front of the northern vestibule.
The aims of this study are:
● introducing the excavations in the Diyarbakır Great Mosque Western Maksurah and explaining the reasons of these excavations;
● presenting the results of these excavations;
● giving information on the excavation findings;
●explaining the importance of research excavations in restoration works.
The evaluations made for the preservation of the excavation findings, which were deemed necessary during the restoration works in the great Mosque, will also be explained in this study.
Peran Akun Instagram Yayasan Sobat Mengajar Indonesia Dalam Menarik Minat Relawan
Authors: Kulsum Nieke Monika , Dewi Charmaninta Putrista , Salim Agus 
Published: December 2022

In this unprecedented situation, social media become one of communication tool that could help people to connected to other people easier. The activities of the Sobat Mengajar Indonesia Foundation (YSMI) used social media (Instagram) to attract young people to teach in their foundation, motivated by the lack of equal distribution of education in Indonesia, especially in remote areas in Indonesia. This foundation was built in 2018, in this case, YSMI participate in the community, especially the Sobang area, Lebak Banten. This research aims to describe the activity in Instagram conduct by YSMI. The research methodology use qualitative research tools such as semi-structures interview, observations non participatory and secondary data from literature study. YSMI has succeeding attract many voluntary from their Instagram activities. Dalam situasi yang belum pernah terjadi sebelumnya, media sosial telah menjadi salah satu alat komunikasi yang dapat membantu orang untuk lebih mudah terhubung dengan orang lain. Kegiatan Yayasan Sobat Mengajar Indonesia (YSMI) menggunakan media sosial (Instagram) untuk menarik anak muda untuk mengajar di yayasannya, dilatarbelakangi dengan belum meratanya pendidikan di Indonesia, khususnya di daerah-daerah terpencil. Yayasan yang berdiri pada tahun 2018, dalam hal ini, YSMI ikut berpartisipasi di masyarakat khususnya di daerah Sobang, Lebak Banten. Penelitian ini bertujuan untuk mendeskripsikan aktivitas pemanfaatan media sosial Instagram yang dilakukan oleh YSMI. Metodologi penelitian menggunakan alat penelitian kualitatif berupa wawancara semi terstruktur, observasi non partisipatif dan data sekunder dari studi pustaka. Hasil dari penelitian ini menjelaskan bahwa kegiatan YSMI berhasil menarik banyak relawan dari aktivitas Instagram mereka.
Pengaruh Budaya Digital dan Disiplin Kerja Terhadap Kinerja Pegawai di Masa WFH di Ditjen Dukcapil Tahun 2020-2021
Authors: Suparman Rendy Chandra , Sugiyanto Eko 
Published: December 2022

The Covid 19 pandemic in year 2020 affected many organizations. Work From Home (WFH) policy is the new work methods in Indonesia, especially in a public organization. Employee performance when Work From Home becomes concern for organizations and superiors, because employees are required to achieve the same targets as during Work From Office. The purposes of this paper to ˑfind ˑout the influence ˑof digitalˑculture ˑand work discipline ˑon employee performance during the Work From Home period at Direktorat Jenderal Kependudukan & Pencatatan Sipil (Ditjen Dukcapil) Kemendagri in 2020-2021. The research method used quantitative method with multiple linear regression analysis. The sample in this study are 82 employees at Ditjen Dukcapil in 2020-2021. The analysis results show, digital culture significantly affect employee performance. which has a significance value of 0.021 (p<0.05). On the work discipline variable, significance of 0.028 (p <0.05), these results indicate that there is a significantˑ effect of workˑ discipline ˑon employeeˑ performance during the Work From Home period. Theˑ results of thisˑ study also explain that there is a simultaneous influence of digital culture & work discipline on employee performance during Work From Home at Ditjen Dukcapil in 2020-2021, which is shown from the results of the influence value of 25% with a significanceˑ level of 0.000 (p< 0.05). Pandemi Covid 19 di tahun 2020 berdampak pada banyak organisasi. Kebijakan Work From Home (WFH) merupakan cara kerja baru di Indonesia, khususnya di organisasi publik. Kinerja karyawan saat Work From Home menjadi perhatian bagi organisasi maupun atasan, karena karyawan dituntut untuk mencapai target yang sama seperti saat Work From Office. Tujuan dari penulisan ini adalah untuk mengetahui pengaruh budaya digital dan disiplin kerja terhadap kinerja pegawai di masa Work From Home di Direktorat Jenderal Kependudukan & Pencatatan Sipil (Ditjen Dukcapil) Kemendagri tahun 2020-2021. Metode penelitian yang digunakan yaitu metode kuantitatif dengan analisis regresi linier berganda dengan sampel 82 pegawai di Ditjen Dukcapil. Hasil penelitian menunjukkan adanya pengaruh yang signifikan budaya digital terhadap kinerja pegawai di masa Work From Home di Ditjen Dukcapil dimana memiliki nilai signifikansi 0,021 (p<0,05) atau 20%. Pada variabel disiplin kerja, didapatkan hasil signifikansi sebesar 0,028 (p<0,05) atau 19%. Selanjutnya, hasil penelitian ini juga menjelaskan bahwa terdapat pengaruh secara simultan budaya digital & disiplin kerja terhadap kinerja pegawai di masa Work From Home di Ditjen Dukcapil, dimana ditunjukkan dari hasil nilai pengaruh sebesar 39% dengan taraf signifikansi 0,000 (p< 0,05).
Pakistan Brain Tumour Epidemiology Study (PBTES): Uncovering the Hidden Burden of Brain Tumours in the Country
Authors: Syed Ather Enam  , Sameen Siddiqi  , Mohammad Hamza Bajwa  , Mashal Murad Shah  , Muhammad Usman Khalid  
Published: December 2022

Epidemiological studies have significantly helped determine the burden, types, and geographical distribution of brain tumours in HICs (highincome countries). However, brain tumour data from low-and-middle-income countries is often sparse, focusing on a few centres1. The situation in Pakistan is no different. Few oncological registries exist in our region that focus on common tumours. Collecting data regarding brain tumours has been challenging, as evidenced by the underreported incidence of brain tumours by centers such as the Karachi Cancer Registry (KCR), Pakistan Atomic Energy Commission (PAEC) report, and GLOBOCAN. Brain tumours are distinct from other cancer types by having more than 200 subtypes, requiring complex analysis, grading, and personalized therapeutic strategies. Moreover, there is no current standardized system to record brain tumour patient data, making it difficult to collate data from various centers.
Continue.
Distance travelled for brain tumour surgery: A Low- and Middle-income Country Perspective
Authors: Mohammad Hamza Bajwa   , Mashal Murad Shah  , Muhammad Usman Khalid  , Ahsan Ali Khan  , Nida Zahid   , Saad bin Anis   , Naveed Zaman Akhunzada   , Altaf Ali Laghari  , Muhammad Faraz Raghib  , Sameen Siddiqi  , Syed Ather Enam  
Published: December 2022

Objective: To examine the effect of distance travelled for brain tumour surgery on patient outcomes in an LMIC.
Methods: Data were collected as part of the Pakistan Brain Tumour Epidemiology Study (PBTES) for brain tumour patients who underwent surgery in 2019. Mapping software was used to calculate the distance travelled by each patient from their primary address to the hospital. This was analysed in correlation with outcomes (change in KPS score, current status) and demographic variables.
Results: Of 2366 patients, the median distance travelled across the country was 104 km (IQR: 9.07 - 304). Only 970 (41%) patients had access to brain tumour surgical care within 50 km of their primary address. A total of 372 (15.7%) patients requiring brain tumour surgery had to travel more than 500 km to reach their primary care hospital. Patients travelling more than 50 km for brain tumour surgery had better pre- and post-surgery Karnofsky performance scores (p<0.001) than those travelling less than 50 km. The overall survival for these patients was also better (82.4% vs 75.7%, p= 0.002) compared to patients travelling less than 50 km.
Conclusion: The distance to a hospital dictates a patient's access to continuity of care through adjuvant chemoradiotherapy and regular follow-ups. Less than half of brain tumour patients in Pakistan had access to brain tumour surgery care within 50 km of their homes. Overall outcomes were significantly better in patients travelling more than 50km for neurosurgical care - suggesting a distance bias effect.
Keywords: Distance travelled, Health disparities, Neuro-oncology, LMIC, Cancer epidemiology.
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Prioritizing Pituitary Adenoma Care apart from Pakistan: Analysis from an Epidemiological Study
Authors: Mashal Murad Shah  , Mohammad Hamza Bajwa  , Muhammad Usman Khalid  , Rashid Jooma  , Saad bin Anis  , Altaf Ali Laghari   , Muhammad Faraz Raghib  , Naveed Zaman Akhunzada   , Sameen Siddiqi   , Syed Ather Enam   
Published: December 2022

Objective: To identify symptoms and risk factors and promptly diagnose, treat, and manage pituitary adenomas. Prioritizing care for pituitary adenomas will reduce the prolonged disability.
Methods: Patients with a histopathological diagnosis of a pituitary adenoma that presented at 32 tertiary care neurosurgical centres were included. The information recorded included demographics, treatment methods, adjuvant chemoradiotherapy and loss to follow-up. Data on tumour size, functionality, and laterality were collected.
Results: Of the 32 hospitals surveyed, 24 operated on pituitary adenomas, and treated 277 patients. The mean age at diagnosis was 39.8 ± 13 years, with a majority of males (63.5%) being diagnosed than females. Paediatric cases constituted only 4.7% of the total pituitary adenomas operated upon. Gross total resection was reported for 155 (56%) of all pituitary adenoma patients. Majority of the patients affected by pituitary adenomas (80.1%) were from the working class.
Conclusion: Highlighting care for non-malignant brain tumours is important for Pakistan's health system. Evidence
pertaining to gender and age disparities indicates that males in the younger age groups are predominantly affected,
which takes a large socio-economic toll on patients and their households. This study also highlights the need to
incorporate digital health technologies for postoperative follow-up and adjuvant treatment.
Keywords: Pituitary Neoplasms, Chemoradiotherapy, Healthcare, Socioeconomic Factors, Demography.
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ANALISA PEMBANGKIT TENAGA LISTRIK DENGAN TENAGA UAP DI PLTU
Authors: Abbas Hammada , Jamaluddin Jamaluddin , Amiruddin Amiruddin 
Published: December 2022

Pembangkit Listrik Tenaga Uap (PLTU) adalah pembangkit yang mengandalkan energi kinetik dari uap untuk menghasilkan energi listrik. Tujuan penelitian ini adalah untuk mengetahui daya yang dibangkitkan oleh turbin dan energi kalor yang dibutuhkan oleh boiler. Metode penelitian yang dilakukan adalah metode observasi dan pengelompokan sumber data yang diperlukan seperti kondisi dan pola produksi steam pada boiler, turbin dan mengidentifikasi data-data tersebut kemudian dilakukan perhitungan pada data yang ada. Hasil penelitian boiler menunjukan SUPERHEATED STEAM PRESSURE pada hari pertama sebesar 9.652 Mpa dan SUPERHEATED STEAM TEMP sebesar 515.367 C serta daya maksimum yang dibangkitkan turbin sebesar 110.758 MW. Hasil perhitungan menunjukan daya maksimum turbin yang dibangkitkan selama satu jam adalah 246,526 MW sedangkan pada hari pertama panas spesifik yang dibutuhkan boiler (qboiler) adalah sebesar 3.212,2 KJ/kg. Kesimpulan besar daya maksimum yang dibangkitkan oleh turbin uap pada PLTU selama seminggu adalah 241,424 MW sedangkan kapasitas energi kalor (Qboiler) yang dihasilkan oleh boiler adalah 278,576 MW.
“Gender Trouble” in the New Hindi Novel
Authors: Castaing Anne 
Published: December 2022

Some recent studies aim at highlighting the way post-independence Indian literature can reveal the ambiguities linked to the representation of the “self,” whose “Indianness” rested on both indigenous and exogenous sources, in a continuous dialogue with Western form of discourses (Marxism, psychoanalysis, and existentialism, for example). The gender issue remained nevertheless relatively excluded from these debates. It is undeniable that the development of Western feminist discourses and Gender Studies since the 1960s, from Simone de Beauvoir to Judith Butler, significantly modified the representation of woman and womanhood. Indeed, in the field of social science, many studies aim at deconstructing the mythic model of the docile and silent “Oriental” woman, represented by the figure of Sītā, and at underlining, even stimulating her empowerment, thus radically opposing the passivity of Indian traditional women with a militant feminism nurtured by the ideal of gender equality and even gender indetermination.
Nevertheless, cultural forms, performances or productions can reveal porosities between these two opposed representations. By exploring two recent Hindi novels (K. B. Vaid’s Līlā, 1990, and Mridula Garg’s Kaṭ hgulāb, 1996), whose polyphonic structure allows the empowerment of women within the narrative space, this paper aims at underlining the way literary feminism can also rest on a composite and complex representation of womanhood which constantly re-negotiates its models and can also be nourished by traditional sources. The gender question and the fluidity of this notion are not only echoed, but also find their roots in an indigenous mythical ethos, whose paradigms cannot be reduced to an essential manhood and womanhood. This paper thus interrogates the cultural specificities of this “gender trouble” in the Indian context, showing that feminism in this particular background can lay on a re-interpretation of traditions rather than on a radical break with them.
Tracking the Dragon across the Ancient Near East
Authors: Miller Robert D. 
Published: December 2022

Calvert Watkins definitively illustrated the connections between the Vedics laying of the dragon Vr̥tra by the thunder-god Indra and the storm-god dragon slaying myths of the both ancient Iran (Aži Dahāka) and Indo-European Hittites (Illuyanka). But there are actually two Hittite dragon-slaying myths – the other, Hurrian in origin, concerning the storm god Teshub – and the relationship between the two remains unclear. The Hurrian-Hittite myth clearly underlies the Canaanite storm-god dragon slaying, but the connection of the latter to an independent Semitic dragon-slaying myth is also unclear. Is there a separate Semitic myth at all, or does the dissemination of these mythological motifs all go back to Indo-European Hittites and Indo-Europeans among the Hurrians? And if there is a Semitic myth, did it disseminate from the Levant southeastward to Mesopotamia with the spread of the Amorites in the early 2nd millennium or was there an originally-Sumerian dragon-slaying myth already in Southern Mesopotamia? And what are we to do when specificmotifsoftheearliest Mesopotamian form reappear in the late Iranian Shahname? This essay tracks the dragon across the ancient Near East, as similar myths fed into each other, their elements interweaving and combining in new forms.