bluuebunny/crossref_metadata_2025_split huggingface dataset:
Petroleum++: ATCE, Financial Results, and GEODE
Authors: Kamal Medhat M. 
Published: July 2023

The Annual Technical Conference and Exhibition (ATCE), SPE’s flagship event, will be held in San Antonio, Texas, from 16–18 October. I encourage all members to seriously consider attending ATCE this year to benefit from the knowledge sharing presented by fellow members across all disciplines of petroleum engineering.
Some SPE conferences are topically focused, such as the reservoir simulation, hydraulic fracturing, and HSE conferences. ATCE, on the other hand, is the conference where all petroleum engineering and related disciplines are discussed and serves as a barometer to help professionals gauge which specific competencies are needed now and in the future. It is also important that we are aware of the developments and the changes in other technical areas and of the directions our industry is taking based on the changes in economic, political, and technical arenas. ATCE is an excellent venue for all of us to obtain a broad range of information and trends.
I am sure that most of our members are also aware of the additional benefits that may be obtained through attending ATCE. We know of the extensive exhibits where service, technology, and manufacturing companies provide members with the latest developments and enhanced products. Some national and international organizations show their work and major projects. All discuss developments that are affecting our profession and provide guidance about what we need to know to continue having successful and enjoyable careers.
Another advantage of attending ATCE is the ability to network with our colleagues and friends throughout the industry. We usually get a chance to meet with friends that we have not seen for a while and to create new friendships with members that we meet during the conference.
One of my favorite activities during ATCE is the alumni receptions. I always look forward to catching up with my classmates from my universities and learning from their experiences. This year, ATCE promises to provide all the benefits I just described as we welcome people back to our in-person events after the COVID-19 pandemic. It is encouraging that more and more of our members are coming back and attending events after we lost this opportunity for several years.
As a member of the SPE Legion of Honor, I had the opportunity to attend numerous ATCEs starting with my first conference in 1973 held in Las Vegas. I’ve attended and enjoyed every ATCE since then, minus one I was unable to attend in Calgary.
I would like share with you some of the history of ATCE since its inception in 1924. The conference in San Antonio will be the 100th edition of ATCE. As most of our members know, SPE was originally the petroleum branch of the American Institute of Petroleum and Metallurgical Engineering (AIME). It became its own society in 1957, and in 1958, ATCE was held in Houston. The event rotated between several US cities since and was held for the first time outside the US in Florence, Italy, in 2010.
Journey to an “A” Grade Gas Certification
Authors: Kyrylovych Mike 
Published: July 2023

The August 2022 issue of JPT featured an article on the most common voluntary certifications that have at least some kind of methane emissions-related requirements. Since then, MiQ appears to have become a certification framework of choice for many industry players. According to Georges Tijbosch, CEO of MiQ, as of January 2023, about 20% of US natural gas production has gone through the MiQ process. Tijbosch noted that most of the currently certified production received grades A, B, or C.
While this is no high school, we naturally tend to assume that getting an “A” is the ultimate goal of getting certified. It might be true for some; however, as we all realize after graduating schools and universities and upon entering the workforce, life is quite often more about continuous improvement over time vs. achieving the top grade as such.
This article is aimed at exploring the MiQ grading framework in more detail and explaining practical pathways for industry participants to achieve any desired MiQ grade. For simplicity, we will focus on the MiQ Standard—Onshore Production, but the fundamental concepts are applicable to other industry segments.
The MiQ Standard scores a facility based on three broad categories.
- Methane-intensity quantitative metric
- Monitoring technology deployment
- Company practices related to the methane emissions management
Each of these categories is scored by an auditor accredited to conduct MiQ audits and who is an independent subject matter expert in the fields of methane mitigation, monitoring, and accounting. The combined score across the three categories results in a letter grade on the MiQ certificate issued for that facility’s production. Natural gas buyers (typically utility companies or industrial users) then request certain volumes of certified gas and, depending on the targeted end use and other factors, may specify a desired grade.
Roy Hartstein is an emissions subject matter expert, as well as founder and president of Responsible Energy Solutions, an organization that performs certification assessments and helps companies prepare for certification. Hartstein and his team have conducted over a dozen MiQ audits. He talks about three aspects of value that motivate natural gas producers to improve from a non-A to an A grade: 1) possibility of earning a higher premium on the sold certified gas; 2) internal risk management across several avenues such as safety, identification of malfunctioning equipment, or early detection of operational inefficiencies; and 3) alleviating environmental concerns of the investment community. He believes this advances a long-term strategy to secure oil and gas’s potential as part of the future energy mix.
Regardless of the underlying motivation, most of us like to think we are straight-A students and don’t want to bring home a report card with a lower grade. But at the time a company initiates the certification process, they may find they qualify for a lower (i.e., non-A) grade. What are the potential implications of this?
The Nexus of ESG and Environmental Sustainability: Does Gender Diversity Make a Difference in Asian Companies?
Authors: Saleh Mohammed W.A. 
Published: July 2023

Abstract
This study examines the association between Environmental, Social, and Governance (ESG) and Environmental Sustainability Performance (ESP), focusing on the moderating role of gender diversity on the board (BGD) in Asian companies listed from 2005–2019. Model 1 is estimated using the GMM system to investigate the association between ESP and ESG, while Model 2 examines the moderating effect of BGD on this association. The results reveal a significant association between ESP and the ESG score, with BGD strengthening this relationship. This research contributes to the literature on ESG and sustainability by offering evidence of the role of BGD in enhancing sustainability performance. Furthermore, this study has significant implications for policymakers, highlighting the importance of monitoring and evaluating listed companies to ensure they receive higher ESG ratings. Encouraging firms to disclose their energy use and minimize pollution can improve their ESG score, benefitting society.
Detection of urban flood inundation from traffic images using deep learning methods
Authors: zhong pengcheng , Liu Yueyi , Zheng Hang , Zhao Jianshi 
Published: July 2023

Abstract
Urban hydrological monitoring is the basis for urban hydrological analysis and storm flood control. However, current monitoring of urban hydrological data is insufficient, including flood inundation depth. This limits calibration and flood early warning ability of the hydrological model. In response to this limitation, a method for evaluating the depth of urban floods based on image recognition using deep learning was established in this study. This method can identify the submerged positions of pedestrians or vehicles in the image, such as pedestrian legs and car exhaust pipes, using the object recognition model YOLOv4. The mean average precision of water depth recognition in a dataset of 1177 flood images reached 89.29%. The established method extracted on-site, real-time, and continuous water depth data from images or video data provided by existing traffic cameras. This system does not require installation of additional water gauges and thus has a low cost and immediate usability.
Quantitative Analysis of the Impact of Infectious Disease Physicians on Patients in the Emergency Department Fast-Track Parenteral Antibiotics Program
Authors: McSweeney Connor , Steiner Theodore , Grant Jennifer 
Published: July 2023

Abstract
Introduction:
The outpatient parenteral antibiotic therapy (OPAT) program of Vancouver General Hospital (VGH) was supervised solely by emergency physicians (EPs) until 2017 when infectious disease (ID) physicians began assisting in management. We designed a retrospective study to determine whether ID involvement led to improved outcomes.
Methods
This study analyses the impact of this increased ID involvement by comparing the mean days patients spend on OPAT with ID involvement versus EPs alone through a retrospective chart review. Our secondary research objectives were to compare patient care decisions, e.g., antibiotic choice, tests ordered, and final diagnosis.
Results
When directly compared, there was no difference between the mean number of days on OPAT between physician types. Compared to historic patterns, patients seen in OPAT after increased ID consultation spent an average of 0.5 fewer days in the program. However, when grouped by the first day of ID assessment, the average total days in OPAT was closely aligned with the day of first ID assessment, implying that ID frequently discharged patients close to initial assessment. Patients seen by ID were less likely to return within one month of discharge compared to those not seen by ID. Secondary findings include ID physicians prescribing a greater range of antibiotics, providing more varied final diagnoses, prescribing antibiotics less frequently, and ordering more cultures, diagnostic imaging and specialist consults.
Discussion
The findings of this study support the hypothesis that ID involvement in OPAT programs leads to changes in care that may have beneficial outcomes for patients and the healthcare system.
New colours for old in the blue-cheese fungus Penicillium roqueforti
Authors: Dyer Paul , Cleere Matthew , Novodvorska Michaela , Geib Elena , Whittaker Jack , Darbyshir Heather , Salih Nadhira , Hewitt Sarah , Kokolski Matthew , Brock Matthias 
Published: July 2023

Abstract
Penicillium roqueforti is used worldwide in the production of blue-veined cheese. The blue-green colour derives from pigmented spores formed by fungal growth. Using a combination of bioinformatics, targeted gene deletions, and heterologous gene expression we discovered that pigment formation was due to a DHN-melanin biosynthesis pathway. Systematic deletion of pathway genes altered the arising spore colour, yielding white to yellow-green to red-pink-brown phenotypes, demonstrating the potential to generate novel coloured strains. There was no consistent impact on mycophenolic acid production as a result of pathway interruption although levels of roquefortine C were altered in some deletants. Importantly, levels of methyl-ketones associated with blue-cheese flavour were not impacted. UV-induced colour mutants, allowed in food production, were then generated. A range of colours were obtained and certain phenotypes were successfully mapped to pathway gene mutations. Selected colour mutants were subsequently used in cheese production and generated expected novel colourations with no elevated mycotoxins, offering the exciting prospect of use in future cheese manufacture.
Difference in S. Mutans Serotype C Genomic Variability Comparing Pulsed Field Electrophoresis and Whole Genome Sequencing.
Authors: Rincón-Rodríguez Ramiro Javier , Bedoya-Correa Claudia María , Herrera-Patiño Juan Carlos , Arboleda-Toro David 
Published: July 2023

Abstract
Objective: The aim of this study was to compare in silico, the genetic variability of the restriction patterns obtained by pulsed field gel electrophoresis (PFGE), with the global and specific patterns obtained from whole genome sequencing (WGS) of S. mutansserotype c and their relationship with their pathophysiology.
Materials and Methods: Reactivated S. mutans UA159 (reference strain), isolates P20MB6, P21S6, P18C3 and P28MB7, molecularly identified as S. mutans, serotype c. Following DNA extraction, a PFGE was performed to determine genetic variability and analyze the clusters according to the pathophysiology of the strains. WGS bioinformatic analysis of the genome sequences and implementation of the MAUVE system, to identify the global and specific variability of the strains and its relationship with their pathophysiology.
Results: In Streptococcus mutans, serotype c, PFGE showed variability between strains, but neither separate clusters according to their pathophysiology, nor indicate where the variability was. WGS evidenced the variability present in the sequences, contents and genomic order, associating these changes to the physiopathological behavior of the strains.
Conclusion: PFGE is useful for screening bacterial safety and virulence. However, it cannot separate the bacterial clusters according to their pathophysiological behavior and thus partially identifies genetic variability. PFGE. Conversely, WGS unveils genetic variability and associate it to the pathophysiological behavior of the studied bacteria.
Exhaustive identification of genome-wide binding events of transcriptional regulators with ICEBERG
Authors: Cantù Claudio , Nordin Anna , Pagella Pierfrancesco , Zambanini Gianluca 
Published: July 2023

Abstract
Genome-wide protein interaction assays aspire to map the complete binding pattern of gene regulators. However, common practice relies on replication and high stringency statistics which favor false negatives over false positives, thereby excluding portions of signal which may represent biologically relevant events. Here, we present ICEBERG (Increased Capture of Enrichment By Exhaustive Replicate aGgregation), an experimental and analytical pipeline that harnesses large numbers of CUT&RUN replicates to discover the full set of binding events and chart the line between false positives and false negatives. We employed ICEBERG to map the full set of H3K4me3-marked regulatory regions and β-catenin targets in human colorectal cancer cells. The ICEBERG datasets allow benchmarking of individual replicates, comparison of the performance of peak calling and replication approaches and expose the arbitrary nature of other strategies to identify reproducible peaks. Instead of a static view of genomic targets, ICEBERG established a spectrum of detection probabilities across the genome for a given factor, underlying the intrinsic dynamicity of its mechanism of action, and permitting to distinguish frequent from rare regulation events. Finally, ICEBERG discovered instances, undetectable with other approaches, that might underlie novel mechanisms of colorectal cancer progression.
Development of the Public Law-Abiding Beliefs and Practices Scale (PLABPS) and the relationship between health-related and non-health-related behaviors
Authors: Shiraly Ramin , Jeihooni Ali Khani , Mir Fazal Irshad , Griffiths Mark D. 
Published: July 2023

Abstract

Background: Interactions between social and personal behavioral choices might explain why individuals behave differently with respect to public laws and regulations, some of which are known to influence individuals’ health. Evaluation of such interactions needs valid assessment tools.
Objectives: The primary objective of the present study was to develop and validate the Public Law-Abiding Beliefs and Practices Scale (PLABPS). The second objective was to examine whether there was a significant association between health-related and non-health-related behaviors (including COVID-19 preventive behaviors).
Methods: To develop the scale, several steps were taken including item suggestion, discussion by an expert panel, performing a pilot study on the initial scale, sequential item reduction to maximize internal consistency using exploratory and confirmatory factor analysis, and finalizing the scale items through expert review. Data were collected from 1108 community-dwelling individuals aged 18 years and older. Internal consistency and construct validity of the PLABPS were examined.
Results: A 10-item scale comprising two factors was extracted showing good psychometric properties. Confirmatory factor analysis results demonstrated good model fit indices (CMIN/DF: 2.340, SRMR = 0.053, RMSEA= 0.067, CFI= 0.960). The Cronbach alpha was 0.86 suggesting very good internal consistency. There was a significantly moderate association between PLABPS scores and COVID-19 preventive behaviors, indicating that individuals with greater law-abiding tendency were more likely to follow preventive COVID-19 behaviors.
Conclusion: The PLABPS is a reliable and valid brief instrument for assessing individuals’ adherence to general public laws. The scale may predict COVID-19 protective behaviors and other health-related behaviors. Given its potential use with regard to psychosocial issues, the PLABPS may contribute to worldwide research in social and behavioral science fields.
Network representations of attractors for change point detection
Authors: Tan Eugene , Algar Shannon , Correa Debora , Stemler Thomas , Small Michael 
Published: July 2023

Abstract
A common approach of monitoring the status of physical and biological systems is through the regular measurement of various system parameters. Changes in a system's underlying dynamics manifest as changes in the behaviour of the observed time series. For example, the transition from healthy cardiac activity to ventricular fibrillation results in erratic dynamics in measured electrocardiogram (ECG) signals. Identifying these transitions -- change point detection -- can be valuable in preparing responses to mitigate the effects of undesirable system changes. Here, we present a data-driven method of detecting change points using a phase space approach. Delay embedded trajectories are used to construct an `attractor network', a discrete Markov-chain representation of the system's attractor. Once constructed, the attractor network is used to assess the level of surprise of future observations where unusual movements in phase space are assigned high surprise scores. Persistent high surprise scores indicate deviations from the attractor and are used to infer change points. Using our approach, we find that the attractor network is effective in automatically detecting the onset of ventricular fibrillation (VF) from observed ECG data. We also test the flexibility of our method on artificial data sets and demonstrate its ability to distinguish between normal and surrogate time series.
Zinc-l-selenomethionine in diets of broiler chickens subjected to cyclic heat stress
Authors: Tesser Guilherme Luis Silva , Junior Nilton Rohloff , Campos Felipe Potenza , Costa Ana Paula Guimarães Cruz , Sartor Heloísa , Kaufmann Cristine , Junior José Geraldo de Vargas , Eyng Cinthia , Nunes Ricardo Vianna 
Published: July 2023

Abstract
Limited information exists on the effects of zinc-l-selenomethionine (Zn-L-SeMet) in broiler diets under cyclic heat stress. Hence, this study aimed to investigate its impact on broiler diets from 1 to 42 days of age reared under cyclic heat stress. A total of 1,000 male Cobb 500® broiler chicks were assigned to five treatments: 0, 0.15, 0.23, 0.47 and 1.30 mg/kg of Zn-L-SeMet. Each treatment consisted of 10 replicates with 20 birds each. Animals fed diets with 1.30 mg had reduced feed intake (FI) compared to the other treatments (p < 0.05) and lower feed conversion ratio (FCR) compared to animals that were fed 0.15, 0.47 mg, and control diets (p < 0.05). Both FI and FCR reduced linearly. Mortality was lower in broilers that were fed diets with 0.15 mg compared to the control (p < 0.05) diet. The inclusion of 0.71 mg was estimated to reduce bird mortality. Broilers fed diets with 0.47 mg had higher triglyceride (TRG) levels (p < 0.05) than those fed with 0.15, 0.23, and 1.30 mg diets. The inclusion of 0.97 mg was predicted to increase TRG levels. Broilers fed diets with 0.47 mg had reduced gamaglutamiltransferase (GGT) levels than those fed with the control diet. In addition, the inclusion of 1.19 mg was predicted to reduce GGT levels. There was no effect of the diets on insulin-like growth factor 1 and growth hormone receptor hormones gene expression. In conclusion, the inclusion of 1.30 mg/kg of Zn-L-SeMet in heat-stressed broiler diets is recommended to achieve the best growth performance from 1 to 42 days of age.
Pharmacokinetic and Pharmacodynamic Analyses of Nafamostat in ECMO Patients: A Comparative Study of Central Vein and ECMO Machine Samples
Authors: Lee Dong-Hwan , Lee Jae Ha , Jang Ji Hoon , Kim Yong Kyun , Kang Gaeun , Jung So Young , Kim Dae-Wook , Jang Hang-Jea 
Published: July 2023

Abstract

Background
This study addresses the knowledge gap concerning the optimal dosage adjustment of nafamostat mesylate in extracorporeal membrane oxygenation (ECMO) by investigating its pharmacokinetics/pharmacodynamics properties. Specifically, we examine the exposure-response relationship between nafamostat concentration and activated partial thromboplastin time (aPTT) in ECMO patients.
Methods
Prospectively, 24 patients were enrolled in this study. Nafamostat infusion was administered continuously through a dedicated stopcock in the drainage pathway before the ECMO pump, starting at 15 mg/h. The maintenance dose of nafamostat was adjusted to maintain the target aPTT range of 40 to 80 seconds. Blood samples were collected from both the patient's central venous catheter and the ECMO circuit. Pharmacokinetics/pharmacodynamics analyses were performed using a nonlinear mixed effects model.
Results
The time-varying nafamostat concentrations measured from patient catheter and ECMO circuit were best described by a two-compartment model. In the patient model, the clearance was 189 L/h, and the steady-state volume of distribution was 62.01 L. In the ECMO model, the clearance was 85.2 L/h, and the steady-state volume of distribution was 40.63 L. The mechanism by which the anticoagulant effect of nafamostat increased aPTT in both models was well explained by a turnover model in which increasing concentration of nafamostat inhibited the decrease in aPTT. In the patient model, nafamostat was found to decrease the rate constant for aPTT reduction by up to 35.5%, with an IC50 of 350 µg/L. In the ECMO model, nafamostat was observed to decrease the rate constant for aPTT reduction by up to 43.6%, with an IC50 of 581 µg/L.
Conclusions
When developing the pharmacokinetics/pharmacodynamics model of nafamostat using patient and ECMO samples, we employed two-compartment and turnover models for pharmacokinetics and pharmacodynamics, respectively. Notably, there were substantial differences in the estimated parameter values. Considering the substantial interindividual variability observed in the pharmacokinetics/pharmacodynamics of nafamostat, the development of a highly predictive model that incorporates relevant covariates and considers the sampling site holds great promise in achieving desired anticoagulant effects, particularly in ECMO-treated patients who are at a heightened risk of bleeding.