bluuebunny/crossref_metadata_2025_split huggingface dataset:
REMOTE FITNESS AS PART OF INFORMATION AND COMMUNICATION TECHNOLOGIES OF PHYSICAL CULTURE AND RECREATION ACTIVITIES OF THE ABLE-BODIED POPULATION OF RUSSIA
Authors: Буянов Валерий Николаевич , Кашина Светлана Георгиевна 
Published: August 2023

На основе анализа статистических данных о физкультурно-оздоровительной деятельности трудоспособного населения России выявлены причины, не позволившие достигнуть их целевого показателя на период до 2022 года. Выявлены основные преимущества использования в составе информационно-коммуникативных технологий физкультурно-оздоровительной деятельности населения дистанционного (онлайн) фитнеса.
Based on the analysis of statistical data on the physical culture and recreation activities of the able-bodied population of Russia, the reasons that did not allow them to achieve their target for the period up to 2022 have been identified. The main advantages of using remote (online) fitness as part of information and communication technologies of physical culture and recreation activities of the population are revealed.
A Search for Relativistic Ejecta in a Sample of ZTF Broad-lined Type Ic Supernovae
Authors: Corsi Alessandra , Ho Anna Y. Q. , Cenko S. Bradley , Kulkarni Shrinivas R. , Anand Shreya , Yang Sheng , Sollerman Jesper , Srinivasaragavan Gokul P. , Omand Conor M. B. , Balasubramanian Arvind , Frail Dale A. , Fremling Christoffer , Perley Daniel A. , Yao Yuhan , Dahiwale Aishwarya S. , De Kishalay , Dugas Alison , Hankins Matthew , Jencson Jacob , Kasliwal Mansi M. , Tzanidakis Anastasios , Bellm Eric C. , Laher Russ R. , Masci Frank J. , Purdum Josiah N. , Regnault Nicolas 
Published: August 2023

Abstract
The dividing line between gamma-ray bursts (GRBs) and ordinary stripped-envelope core-collapse supernovae (SNe) is yet to be fully understood. Observationally mapping the variety of ejecta outcomes (ultrarelativistic, mildly relativistic, or nonrelativistic) in SNe of Type Ic with broad lines (Ic-BL) can provide a key test to stellar explosion models. However, this requires large samples of the rare SN Ic-BL events with follow-up observations in the radio, where fast ejecta can be probed largely free of geometry and viewing angle effects. Here, we present the results of a radio (and X-ray) follow-up campaign of 16 SNe Ic-BL detected by the Zwicky Transient Facility (ZTF). Our radio campaign resulted in four counterpart detections and 12 deep upper limits. None of the events in our sample is as relativistic as SN 1998bw and we constrain the fraction of SN 1998bw-like explosions to <19% (3σ Gaussian equivalent), a factor of ≈2 smaller than previously established. We exclude relativistic ejecta with radio luminosity densities in between ≈5 × 1027 erg s−1 Hz−1 and ≈1029 erg s−1 Hz−1 at t ≳ 20 days since explosion for ≈60% of the events in our sample. This shows that SNe Ic-BL similar to the GRB-associated SNe 1998bw, 2003lw, and 2010bh, or to the relativistic SNe 2009bb and iPTF17cw, are rare. Our results also exclude an association of the SNe Ic-BL in our sample with largely off-axis GRBs with energies E ≳ 1050 erg. The parameter space of SN 2006aj-like events (faint and fast-peaking radio emission) is, on the other hand, left largely unconstrained, and systematically exploring it represents a promising line of future research.
SN 2023ixf—Temporal Development of Hα Emission
Authors: Koenig M. 
Published: August 2023

Abstract
I present a series of spectra of the Type II supernova SN 2023ixf in M101 covering a temporal period of 6 weeks. The latest spectra show a prominent Hα P-Cygni profile with an expansion velocity of 7100 km s−1. In addition to an expanding gas shell, evidence of a possible additional absorption was found. This could be interpreted as an asymmetrical feature in the expanding material of the supernova.
Thermal Properties of the Leading Hemisphere of Callisto Inferred from ALMA Observations
Authors: Camarca Maria , de Kleer Katherine , Butler Bryan , Akins Alex B. , Thelen Alexander , de Pater Imke , Gurwell Mark A. , Moullet Arielle 
Published: August 2023

Abstract
We present a thermal observation of Callisto's leading hemisphere obtained using the Atacama Large Millimeter/submillimeter Array at 0.87 mm (343 GHz). The angular resolution achieved for this observation was ∼0.″16, which for Callisto at the time of this observation (D ∼ 1.″05) was equivalent to ∼six elements across the surface. Our disk-integrated brightness temperature of 116 ± 5 K (8.03 ± 0.40 Jy) is consistent with prior disk-integrated observations. Global surface properties were derived from the observation using a thermophysical model constrained by spacecraft data. We find that models parameterized by two thermal inertia components more accurately fit the data than single thermal inertia models. Our best-fit global parameters adopt a lower thermal inertia of 15–50 J m−2 K−1 s−1/2 and a higher thermal inertia component of 1200–2000 J m−2 K−1 s−1/2, with retrieved millimeter emissivities of 0.89–0.91. We identify several thermally anomalous regions, including spots ∼3 K colder than model predictions colocated with the Valhalla impact basin and a complex of craters in the southern hemisphere; this indicates the presence of materials possessing either a higher thermal inertia or a lower emissivity. A warm region confined to the midlatitudes in these leading hemisphere data may be indicative of regolith property changes due to exogenic sculpting.
Anti-proliferative, anti-migration, and anti-invasion activity of novel hesperidin glycosides in non-small cell lung cancer A549 cells
Authors: Poomipark Natwadee , Chaisin Titaporn , Kaulpiboon Jarunee 
Published: August 2023

Background and purpose:
Several attempts have been made to synthesize and investigate modified flavonoids to improve their potential anticancer efficacy. This study aimed to determine the in vitro anti-viability, anti-migration, and anti-invasive effects of two novel hesperidin glycosides, hesperidin glucoside (HG1) and hesperidin maltoside (HG2), compared to original hesperidin and diosmin.

Experimental approach:
Inhibitory effects on normal (MRC5) and cancer (A549) cell viability of hesperidin glycosides were investigated by the trypan blue and MTS assays. A scratch assay determined the suppressive effects on cancer cell migration, and inhibition of cancer cell invasion was investigated through Matrigel™. The selectivity index (SI), a marker of cell toxicity, was also determined for A549 relative to MRC5 cells.

Findings/Results:
The cell viability trypan blue and MTS assays showed similar results of the inhibition of A549 cancer cells; HG1 and HG2 had lower IC50 than original hesperidin and diosmin. The SI of HG1 and HG2 was > 2 after 72-h culture. Investigation of cell migration showed that HG1 and HG2 inhibited the ability of gap closure in a time- and dose-dependent manner. The infiltration of the Matrigel™-coated filter by A549 cells was suppressed in the presence of HG1 and HG2. This result implied that HG1 and HG2 could inhibit cancer cell invasion.

Conclusion and implication:
Our results suggest the inhibition of cancer cell migration and invasion in a time- and concentration-related manner with a favorable toxic profile. Moreover, HG1 and HG2 appeared potentially better agents than the original hesperidin for future anticancer development.
Metabolomic identification of biochemical changes induced by fluoxetine in an insulinoma cell line (MIN6)
Authors: Ngamratanapaiboon Surachai , Pornchokchai Krittaboon , Wongpitoonmanachai Siriphattarinya , Pholkla Petchlada , Srikornvit Napatarin , Mo Jiajun , Hongthawonsiri Patipol , Yambangyang Pracha , Akrachalanont Pilaslak 
Published: August 2023

Background and purpose:
The use of fluoxetine raises the risk of pancreatic beta-cell dysfunction. However, the specific mechanism behind its mechanism of action in beta cells is unknown. This study investigated the cellular response of MIN6 cells to fluoxetine using untargeted cell-based metabolomics.

Experimental approach:
Metabolic profiling of MIN6 cells was performed using liquid chromatography-high resolution mass spectrometry (LC-HRMS) analysis on samples prepared under optimized conditions, followed by principal component analysis, partial least squares-discriminant analysis, and pair-wise orthogonal projections to latent structures discriminant analyses.

Findings/Results:
Sixty-six metabolites that had been differentially expressed between the control and fluoxetine-treated groups demonstrated that the citric acid cycle is mainly perturbed by fluoxetine treatment.

Conclusion and implications:
The current study provides insights into the molecular mechanisms of fluoxetine effects in MIN6 cells.
Formulation and evaluation of taste-masked oral disintegrating tablet containing tolterodine-loaded montmorillonite
Authors: Taymouri Somayeh , Mostafavi Abolfazl , Talabaki Homa 
Published: August 2023

Background and purpose:
The present study aimed to obtain a taste-masked oral disintegrating tablet (ODT) containing tolterodine tartrate (TT) intercalated into montmorillonite (MMT)

Experimental approach:
The TT-MMT hybrid was prepared by ion exchange reaction. The effect of the initial concentration of TT, MMT, temperature, and pH on the encapsulation efficiency (EE) % of the drug in MMT was evaluated. The selected TT-MMT hybrid was characterized by X-ray diffraction (XRD), Fourier transforms infrared (FTIR), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM). Then, the optimized TT-MMT hybrid was incorporated in the ODT prepared by direct compression method and taste-masking assessment performed by a human test panel.

Findings/Results:
The EE% of TT was in the range of 22.67 to 71.06% in different formulations. It was found that increases in MMT concentration significantly increased EE%. DSC and XRD studies indicated that the TT was intercalated in the MMT interlayer space in an amorphous or molecular state. In-vitro release studies at pH 6.8 showed that the amount of the drug released from the TT-MMT hybrid was negligible for the first 3 min. The post-compression of ODT also showed satisfactory results in terms of friability, hardness, disintegration time, and taste.

Conclusion and implications:
MMT-ODT could be a suitable vehicle for the taste masking of TT, with the potential for use in patients with swallowing problems.
Prevalence and characteristics of psoriasis among a sample of preparatory school students in rural Egypt
Authors: El-Komy Mohamed H.M. , Sayed Khadiga S. , El-Desouky Eman D. , Tawfeek Esraa G. , Aboraia Nesreen M. 
Published: August 2023

Background/objectives
The prevalence of psoriasis shows a worldwide geographic variation ranging from 0 up to 11.8%. This reflects the fact that psoriasis is a complex disease influenced by both genetic and environmental factors. The prevalence of psoriasis in children younger than 18 years of age was reported to be 0.40%; however, data about its true prevalence among children in Egypt and the Middle East region are scanty, especially among younger age groups living in rural areas. This work was performed to explore the prevalence and characteristics of psoriasis among a sample of preparatory school students in a rural community in Fayoum, Egypt.

Patients and methods
This cross-sectional study included 3061 preparatory school students with ages between 13 and 15 years from five rural public preparatory schools in Fayoum, Sinouris rural district. The demographic and disease-related data were collected by an assisted self-administrated questionnaire sheet. Clinical examination of all recruits was performed, and disease data for patients with psoriasis were recorded, including extent of the disease and psoriasis severity using the psoriasis area and severity index score.

Results
The prevalence of psoriasis was 0.1% among all of the examined students in the study, with a female-to-male ratio of 3 to 1. The most important triggering factor was changes in seasons and climate, as 50% of the patients worsened in winter. The extent and severity of psoriasis among affected children was mild.

Conclusion
The prevalence and genetic background of psoriasis was low with only mild forms of psoriasis identified among rural preparatory school students in Fayoum, Sinouris district.
Aeroallergen Sensitization Predominates in Children with Atopic Dermatitis
Authors: Seneviratne H. M. Thilanka , Somaratne K. M. K. , Brabaharan Subhani , Bandara G. Dilan Dileepa Jayarathne , Alahakoon A. R. T. Vindya , Senevivikrama Priyanka , Kumarasiri P. V. Rangith 
Published: August 2023

Abstract

Background:
Children with atopic dermatitis (AD) suffer from frequent flare-ups. Correct identification of allergens responsible for flare-ups is important in managing AD. Suspecting food allergens as culprits may result in unnecessary food restrictions which adversely affect the growth of these children. In view of this fact, we aimed to assess the allergen sensitization pattern of children with AD in Sri Lanka.

Objective:
The objective is to assess the food and aeroallergen sensitization pattern of children with AD.

Materials and Methods:
This study was conducted among 100 consecutive patients refereed to the dermatology clinics of a specialized children’s hospital and a tertiary care hospital with the clinical diagnosis of AD. Age ranged from 1 to 18 years. All underwent a Skin prick test (SPT), using prick test solutions for house dust mite Dermatophagoids pteronyssinus (HDM-DP), Aspergillus fumigatus (AF), cat epithelia (CE), cow’s milk (CM), egg white (EW), and peanut.

Results:
Of 100 patients 53.0% had positive SPT for HDM-DP. 15.0% were positive for CE, 9.0% positive for AF. All above three are aeroallergens, food allergen sensitivities were 9.0% for CM, 2.0% for EW, and 1.0% for peanuts. It is of note that the wheal size of HDM-DP SPT showed a very strong correlation with the age of the subject (R
2 = 0.0723, P = 0.007).

Conclusion:
Aeroallergen sensitization predominate over food allergen sensitization in children with AD. HDM and CE were the most common aeroallergen sensitivities. The wheal size of HDM-DP had a very strong positive correlation with age.
Assessment of Oral Health Knowledge of Pharmacists in Two Tertiary Hospitals in Enugu, Nigeria
Authors: Asuquo Bassey B. , Chukwu Ezinne H. , Onyejaka Nneka K. , Uguru Nkoli P. , Amobi Emmanuel O. 
Published: August 2023

ABSTRACT

Introduction:
Oral health is defined as a state of being free of mouth and facial pain, oral infections and sores, and other diseases that limit an individual’s capacity for biting, chewing, smiling, speaking, and psychosocial well-being. This study assessed the knowledge, barriers, and facilitators of oral health knowledge among Pharmacists in Enugu, Nigeria.

Methods:
This was a cross-sectional study of 163 pharmacists in two tertiary hospitals in Enugu, South East, Nigeria. Data on sociodemographic profiles, knowledge of oral health care, barriers, and facilitators of oral health knowledge was collected. Data were analyzed using SPSS version 26 and P < 0.05 was considered significant.

Results:
There were more female 96 (58.9%) than male pharmacists 67 (41.1%). Their mean age was 32.98 ± 8.33 years. The majority of respondents, 56 (34.4%) graduated between 2010 and 2019, and 44 (27%) had additional qualifications. Many of the pharmacists 88 (54%) believed that oral health is part of general health. Also, 107 (65.6%) of the respondents had a good knowledge of oral health while 56 (34.4%) had poor knowledge. There was a significant association between academic qualification (P = 0.04) and having good knowledge of oral health care among pharmacists with those with additional qualifications having better knowledge than the others. Poor creation of oral health awareness by dentists 106 (65.0%) was considered as the main barrier to having good oral health knowledge by the pharmacists.

Conclusion:
More than half of the pharmacists had good knowledge of oral health and academic qualification was associated with having a good knowledge of oral health care among pharmacists in the study population.
Cost-Effectiveness of Cervical Cancer Screening in Rural Bengaluru with Demographic Analysis of Epithelial Cell Abnormalities
Authors: Kaler Amrit Kaur , Rao M. Shilpa , Roopamouli M. , Srinivasalu Y. , Narasimha Raju SNLV , Rao Vishal US 
Published: August 2023

Aim:
Cervical cancer is the fourth-most common cancer in women worldwide and ranks third among all the malignancies for women. In contrast to developed countries, cervical cancer is a public health problem in developing countries like India and accounts for a quarter of the global disease burden. It is also one of the leading causes of cancer mortality in India, accounting for 17% of all cancer deaths among women aged between 30 and 69 years. The aim of this study is to perform a demographic analysis of cervical cancer by using Papanicolaou (PAP) test as a screening modality in Doddaballapur, rural Bengaluru, Karnataka.

Materials and Methods:
A cross-sectional descriptive study was conducted on cervical cancer screening utilizing PAP smear screening. Camps were organized in Doddaballapur, rural Bengaluru, organized by Non-Profit Organization, Sahaya Hastha Trust between December 2017 and 2018. The PAP smears were stained and evaluated for epithelial cell abnormality using Bethesda System criteria free of cost at The Oxford Medical College and Hospital, Bengaluru.

Results:
A total of 647 patients were evaluated in this prospective study and abnormal epithelial cell abnormalities (ECA) were observed in 24 (3.7%) cases. Among the 24 cases, 2 cases (8.3%) of squamous cell carcinoma, 11 cases (45.8%) of atypical squamous cell of undetermined significance, 5 cases (20.8%) of Atypical Squamous cells - cannot rule out high-grade squamous intraepithelial lesion (HSIL), 3 cases (12.5%) of low-grade squamous intraepithelial lesion (3), 2 cases (8.3%) of high-grade squamous intraepithelial lesion (HSIL), and a single case (4.2%) of atypical glandular cells of undetermined significance were noted. Of the remaining 623 smears (96.2%) diagnosed with negative for intraepithelial lesion or malignancy, 428 cases (68.7%) were reported as nonspecific inflammation, while 56 smears (8.9%) showed atrophic smears and 20 cases (3.1%) were unsatisfactory for evaluation. 119 cases (19.1%) displayed a specific infectious etiology; coccobacilli (bacterial vaginosis) being the most common 66 cases (55.5%), followed by Trichomonas vaginalis 46 cases (38.6%) and Candida infection has 7 cases (5.8%).

Conclusions:
In Dodabullapur, a rural Bengaluru suburb, 3.7% of cervical cancer patients had ECA. It is hypothesized that a low-cost screening program is exceptionally beneficial in lowering the disease burden of cervical cancer, especially among middle-aged women and those living in low-income areas. This humanitarian purpose might motivate women in rural regions to be educated with the sole goal of uplifting the impoverished.
Weed detection with Improved Yolov 7
Authors: Peng Mingkang , Zhang Wuping , Li Fuzhong , Xue Qiyuan , Yuan Jialiang , An Peipu 
Published: August 2023

INTRODUCTION: An improved Yolo v7 model.OBJECTIVES: To solve the weed detection and identification in complex field background.METHODS: The dataset was enhanced by online data enhancement, in which the feature extraction, feature fusion and feature point judgment of weed image were carried out by Yolov7 to predict the weed situation corresponding to the prior box. In the enhanced feature extraction part of Yolov7, CBAM, an attention mechanism combining channel and space, is introduced to improve the attention of the algorithm to weeds and strengthen the characteristics of weeds.RESULTS: The mean average precision (mAP ) of the improved algorithm reached 91.15%, which was 2.06% higher than that of the original Yolov7 algorithm. Compared with the current mainstream target detection algorithms Yolox, Yolov5l, Fster RCNN, Yolov4-tiny and Yolov3, the mAP value of the improved algorithm increased by 4.35, 4.51, 5.41, 19.77 and 20.65 percentage points. Weed species can be accurately identified when multiple weeds are adjacent.CONCLUSION: This paper provides a detection model based on Yolov7 for weed detection in the field, which has a good detection effect on weed detection, and lays a research foundation for intelligent weeding robot and spraying robot.
ANALYSIS OF MARKETING STRATEGIES TO IMPROVE STRENGTHENING THE COMPETITION FOR UMKM
Authors: Nst Asrindah , Purba Budiman , Fitria Alya 
Published: August 2023

ABSTRACTMarketing strategy is a measurable approach aimed at making the company’s products known to the general public. Marketing strategy is one way to gain a sustainable competitive advantage either for the company that produces goods or services. Marketing strategies can be used as the basis for preparing the company’s planning. Seeing the problems in the company. So it needs a comprehensive plan that will be used as a guideline for segment companies in conducting their activities, another reason that shows the importance of marketing strategies is the increasingly tight competition of companies in general. The marketing strategy is not only to attract consumers to put the product in the basket, the marketing strategy also ensures that the buyer knows the product offered, verifies and repeats the purchase of the product. Keywords: marketing strategy, competitiveness
Local and Global Praise Strategy
Authors: Kohari Khalis 
Published: August 2023

The study was put forward by Prof. Dr. Hj. Tutty Alawiyah, USA, In this study, he explained the importance of combining da'wah strategies that focus on the local context with those that focus on the global context in spreading Islamic da'wah. He also highlighted how important a good understanding of the social, cultural, and political context is in developing an effective da'wah strategy. This study provides an interesting view of how to spread Islamic da'wah in the current era of globalization in ways that are appropriate to local and global contexts. This study also highlights the importance of understanding local communities' views of life and values when developing da'wah strategies. He stated that da'wah strategies that do not pay attention to the views of life and local community values will be less effective in spreading da'wah. This study also highlights the importance of inter-religious cooperation in spreading Islamic da'wah. He stated that cooperation between religious communities could help reach a wider audience and reduce tensions between religious communities. Is the method used in qualitative methodology helpful in understanding more deeply the social, cultural, and political context in developing effective da'wah strategies, as well as the views of life and local community values that need to be considered in spreading Islamic da'wah? In addition, the qualitative methodology can also assist in identifying the potential for cooperation between religious communities in spreading Islamic da'wah. Overall, this study provides an interesting view of how to spread Islamic da'wah in the current era of globalization in a way appropriate to the local and global context, taking into account the views of life and values of local communities and local cooperation between religious communities.