bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality markers of Dajianzhong decoction based on multicomponent qualitative and quantitative analysis combined with network pharmacology and chemometric analysis
Authors: Xu Yang , Liu Run‐run , Yu Xiao‐jun , Liu Xiao‐nan , Zhang Xin , Jiang Zhi‐hui , Cong Zhu‐feng , Li Qin‐qing , Gao Peng 
Published: September 2023

AbstractIntroductionDajianzhong decoction (DJZD), a classic famous prescription, has a long history of medicinal application. Modern studies have demonstrated its clinical utility in the treatment of postoperative ileus (POI). But none of the current quality evaluation methods for this compound is associated with efficacy.ObjectivesThis study aimed to identify the quality markers (Q‐Markers) connected to the treatment of POI in DJZD.MethodologyUltra‐performance liquid chromatography quadrupole Exactive Orbitrap mass spectrometry (UPLC‐Q‐Exactive Orbitrap‐MS) was used to identify the main constituents in DJZD. Based on the qualitative results obtained by fingerprinting, chemical pattern recognition (CPR) was used to analyse the key components affecting the quality and finally to establish the network of the active ingredients in DJZD with POI.ResultsA total of 64 chemical components were detected. After fingerprint analysis, 13 common peaks were identified. The fingerprint similarity of 15 batches of samples ranged from 0.860 to 1.000. CPR analysis was able to categorically classify 15 batches of DJZD into two groups. And gingerenone A, methyl‐6‐gingerdiol, 6‐gingerol, and hydroxy‐β‐sanshool contributed to their grouping. Twelve common components interact with the therapeutic targets for treating POI. In addition, the mechanism of this prescription for treating POI may be related to the jurisdiction of the neurological system, the immunological system, and the inflammatory response.ConclusionsThis integrated approach can accurately assess and forecast the quality of DJZD, presume the Q‐Markers of DJZD for POI, and lay the foundation for studying the theoretical underpinnings and exploring the mechanism of DJZD in the treatment of POI.
Preparation and characterization of deacetylated cellulose acetate/thermoplastic polyurethane nanofiber membranes modified with graphene oxide for methylene blue and Cr (VI) adsorption
Authors: Si Junhui , Deng Yuanchang , Gong Changxiong , Cui Zhixiang , Wang Qianting 
Published: September 2023

AbstractDeacetylated cellulose acetate/thermoplastic polyurethane@graphene oxide (DA/TPU@GO) nanofibrous membranes were prepared through the combination of electrospinning, deacetylation, and ultrasound‐assisted surface treatment techniques. The morphology, wettability, and mechanical properties of composite nanofiber membranes were studied via SEM, TEM, water contact angle measurements, and mechanical tests. Moreover, the adsorption capacity and mechanism of DA/TPU@GO nanofiber membranes for methylene blue and chromium (Cr (VI)) were analyzed. The introduction of active sites from GO led to a significant increase in the adsorption capacity of the DA/TPU@GO composite membranes compared with the DA/TPU composite nanofiber. The composite membrane featured adsorption capacities of 152.7 mg/g (25°C, pH 3) and 122.1 mg/g (25°C, pH 7) for Cr (VI) and methylene blue, respectively, which are higher than most other composite GO‐based adsorbents. The adsorption mechanism of the DA/TPU@GO composite membrane was consistent with the Langmuir isotherm and second‐order kinetic models. Therefore, the DA/TPU@GO composite nanofiber membrane served as an effective adsorbent with broad application prospects in the sewage treatment field owing to its excellent adsorption capacity.HighlightsNanofibers were prepared for the absorption of methylene blue (MB) and Cr (VI).Nanofibers exhibited adsorption capacities of 152.7 and 122.1 mg/g for Cr (VI) and MB.Adsorption mechanism follows Langmuir isotherm and second‐order kinetic models.Nanofibers have wide potential applications in sewage treatment.
Fabrication of biodegradable kraft paper from buffing dust and jute fiber: Green solutions for packaging
Authors: Noyon Ashikur Rahaman , Karim Suzaul , Rouf Abdur , Jamal Mamun , Layek Rama Kanta , Sivanantham Gokulkumar , Uddin Elias 
Published: September 2023

AbstractAddressing solid waste recycling, this study aims to develop biodegradable kraft paper from buffing dust (BD) and post‐consumed jute fiber (JF). Employing a simple solution casting method with a polyurethane binder, the kraft paper was fabricated and characterized using UV–Vis spectroscopy, FTIR, XRD, SEM, TGA, OTR, biodegradability, and tensile tests. The findings revealed covalent and hydrogen bonding between BD and JF, forming a uniform surface. Notably, the composite exhibited improved thermal stability, enhanced gas barrier properties, and biodegradability compared to individual components. Furthermore, the composite also showed 57% higher tensile strength, 38% greater elongation, 20% increased hardness, and 9% higher density compared to buffing dust. Compared to jute fiber, the increases were 125%, 91%, 30%, and 19% respectively. Moreover, the composite excelled in gas barrier performance, surpassing BD and JF by a remarkable 61% and 73% increase respectively. These significant findings underscore the vast potential of the composite kraft paper as a versatile material suitable for various applications, including packaging, interior furnishing industries, and reinforcing elements in the footwear industry. By addressing waste management and promoting sustainability, this research contributes to the development of eco‐friendly materials that align with contemporary environmental concerns.Highlights
Covalent and hydrogen bonding enhance uniformity.
Biodegradable kraft paper with improved properties.
Impressive tensile strength, elongation, and hardness.
Versatile material for eco‐friendly applications.
Promotes sustainability and waste management.
Impact of amiodarone use on metoprolol concentrations, α‐OH‐metoprolol concentrations, metoprolol dosing and heart rate: A cross‐sectional study
Authors: Robert Sabrina , Pilon Marc‐Olivier , Oussaïd Essaïd , Meloche Maxime , Leclair Grégoire , Jutras Martin , Gaulin Marie‐Josée , Mongrain Ian , Busseuil David , Tardif Jean‐Claude , Dubé Marie‐Pierre , de Denus Simon 
Published: September 2023

AbstractSmall studies suggest that amiodarone is a weak inhibitor of cytochrome P450 (CYP) 2D6. Inhibition of CYP2D6 leads to increases in concentrations of drugs metabolized by the enzyme, such as metoprolol. Considering that both metoprolol and amiodarone have β‐adrenergic blocking properties and that the modest interaction between the two drugs would result in increased metoprolol concentrations, this could lead to a higher risk of bradycardia and atrioventricular block. The primary objective of this study was to evaluate whether metoprolol plasma concentrations collected at random timepoints from patients enrolled in the Montreal Heart Institute Hospital Cohort could be useful in identifying the modest pharmacokinetic interaction between amiodarone and metoprolol. We performed an analysis of a cross‐sectional study, conducted as part of the Montreal Heart Institute Hospital Cohort. All participants were self‐described “White” adults with metoprolol being a part of their daily pharmacotherapy regimen. Of the 999 patients being treated with metoprolol, 36 were also taking amiodarone. Amiodarone use was associated with higher metoprolol concentrations following adjustment for different covariates (p = .0132). Consistently, the association between amiodarone use and lower heart rate was apparent and significant after adjustment for all covariates under study (p = .0001). Our results highlight that single randomly collected blood samples can be leveraged to detect modest pharmacokinetic interactions.
Nano‐selenium foliar intervention‐induced resistance of cucumber to Botrytis cinerea by activating jasmonic acid biosynthesis and regulating phenolic acid and cucurbitacin
Authors: Jia Yujiao , Kang Lu , Wu Yangliu , Zhou Chunran , Cai Runze , Zhang Hui , Li Jiaqi , Chen Zhendong , Kang Dexian , Zhang Li , Pan Canping 
Published: September 2023

AbstractPURPOSE AND METHODSBotrytis cinerea is the primary disease affecting cucumber production. It can be managed by applying pesticides and cultivating disease‐resistant cucumber strains. However, challenges, such as drug resistance in pathogenic bacteria and changes in physiological strains, are obstacles in the effective management of B. cinerea. Nano‐selenium (Nano‐Se) has potential in enhancing crop resistance to biological stress, but the exact mechanism for boosting disease resistance remains unclear. Here, we used metabolomics and transcriptomics to examine how Nano‐Se, as an immune activator, induces plant resistance.RESULTCompared with the control group, the application of 10.0 mg/L Nano‐Se on the cucumber plant's leaf surface resulted in increased levels of chlorophyll, catalase (10.2%), glutathione (326.6%), glutathione peroxidase (52.2%), cucurbitacin (41.40%), and metabolites associated with the phenylpropane synthesis pathway, as well as the total antioxidant capacity (21.3%). Additionally, the expression levels of jasmonic acid (14.8 times) and related synthetic genes, namely LOX (264.1%), LOX4 (224.1%), and AOC2 (309.2%), were up‐regulated. A transcription analysis revealed that the CsaV3_4G002860 gene was up‐regulated in the KEGG enrichment pathway in response to B. cinerea infection following the 10.0 mg/L Nano‐Se treatment.DISCUSSIONIn conclusion, the activation of the phenylpropane biosynthesis and branched‐chain fatty acid pathways by Nano‐Se promotes the accumulation of jasmonic acid and cucurbitacin in cucumber plants. This enhancement enables the plants to exhibit resistance against B. cinerea infections. Additionally, this study identified a potential candidate gene for cucumber resistance to B. cinerea induced by Nano‐Se, thereby laying a theoretical foundation for further research in this area. © 2023 Society of Chemical Industry.
Near‐Video Frame Rate Quantum Sensing Using Hong–Ou–Mandel Interferometry
Authors: Singh Sandeep , Kumar Vimlesh , Sharma Varun , Faccio Daniele , Samanta G. K. 
Published: September 2023

AbstractHong–Ou–Mandel (HOM) interference, bunching of two indistinguishable photons on a balanced beam‐splitter, has emerged as a promising tool for quantum sensing. There is a need for wide spectral‐bandwidth photon pairs (for high‐resolution sensing) with high brightness (for fast sensing). Here, the generation of photon‐pairs with flexible spectral‐bandwidth even using single‐frequency, continuous‐wave diode laser enabling high‐precision, real‐time sensing is showed. Using 1‐mm‐long periodically‐poled KTP crystal, degenerate, photon‐pairs with spectral‐bandwidth of 163.42±1.68 nm are produced resulting in a HOM‐dip width of 4.01±0.04 m to measure a displacement of 60 nm, and sufficiently high brightness to enable the measurement of vibrations with amplitude of 205 ± 0.75 nm and frequency of 8 Hz. Fisher‐information (FI) and maximum likelihood estimation enables optical delay measurements as small as 4.97 nm with precision (Cramér–Rao bound) and accuracy of 0.89 and 0.54 nm, respectively, therefore showing HOM sensing capability for real‐time, precision‐augmented, in‐field quantum sensing applications.
Optimal containment control for a class of heterogeneous multi‐agent systems with actuator faults
Authors: Fan Sijia , Wang Tong , Wu Ju , Qiu Jianbin 
Published: September 2023

AbstractThis article investigates the optimal containment control problem for a class of heterogeneous multi‐agent systems with time‐varying actuator faults and unmatched disturbances based on adaptive dynamic programming. Since there exist unknown input signals in each leader, distributed observers are utilized to estimate trajectories in the convex hull spanned by leaders. The containment control problem is then transformed into an optimal tracking problem. To compensate for the actuator faults and unmatched disturbances, a novel performance index function is designed. We prove that the optimal control policy can ensure that the tracking error system of each follower is uniformly ultimately bounded. The online policy iteration algorithm is implemented using critic neural networks to obtain the optimal control policy. A numerical example is provided to demonstrate the effectiveness of the proposed control policy.
Effects of conservation practices on rainfed maize yield, furrow water infiltration, and soil moisture for surface sealing loam soils in the Yazoo‐Mississippi Delta
Authors: Rix Jacob P. , Lo Tsz Him , Gholson Drew M. , Spencer G. Dave , Singh Gurbir 
Published: September 2023

AbstractDecades of intense tillage have created the problem of surface sealing in loam soils across the Mid‐South United States and beyond. These soils exhibit low organic matter, poor aggregate stability, and ultimately low infiltration rates that decrease rainfed crop productivity and increase irrigation water demand. This research quantified the effects of soil management practices on rainfed maize (Zea mays L.) yield, furrow water infiltration, and soil moisture in Commerce very fine sandy loam and silt loam near Stoneville, MS. The six treatments included conventional tillage (CT), cereal rye (CR; Secale cereale L.), furrow diking (FD), no‐till (NT), polyacrylamide (PAM), and subsoiling (SS). No other treatment achieved a significantly higher maize grain yield than the CT control treatment in both years consistently. Single‐ring infiltrometer results indicated no significant differences among CT, CR, PAM, and SS in 2022 and between CT and NT in 2021. Neutron attenuation found that total soil water within the top 1 m was not significantly different among CT, FD, and SS on any of the eight measurement dates throughout the 2022 maize reproductive period. However, soil moisture was numerically lower for FD in the late reproductive stages. These findings suggest that environmental factors and other agronomic operations may counteract conservation practices, limiting their effectiveness at reducing irrigation requirements to mitigate groundwater depletion in the Mississippi River Valley Alluvial Aquifer.
Understand ASD differences in women for accurate referral, diagnosis, accommodations
Authors: Bedrossian Louise 
Published: September 2023

Leo Kanner (1943) and Hans Asperger (1944), whose studies included only boys, initially and independently  identified autism, noting three basic characteristics: (1) social difficulties, (2) communication problems, and (3) repetitive and restrictive activities. But it wasn’t until 1980 that the term “autism” appeared in the Diagnostic and Statistical Manual of Mental Disorders‐III. Not until 1994 did Asperger's syndrome, or high‐functioning autism, appear in the DSM‐IV. And in the 2013 DSM‐5, Asperger's syndrome disappeared, merging into the integrated category of autism spectrum disorder.
Spherical Shell with CNTs Network Structuring Fe‐Based Alluaudite Na2+2δFe2−δ(SO4)3 Cathode and Novel Phase Transition Mechanism for Sodium‐Ion Battery
Authors: Yang Wei , Liu Qi , Hou Lijuan , Yang Qiang , Mu Daobin , Tan Guoqiang , Li Li , Chen Renjie , Wu Feng 
Published: September 2023

AbstractIron‐based sulfate cathodes of alluaudite Na2+2δFe2−δ(SO4)3 (NFS) in sodium‐ion batteries with low cost, steady cycling performance, and high voltage are promising for grid‐scale energy storage systems. However, the poor electronic conductivity and the limited understanding of the phase‐evolution of precursors hinder obtaining high‐rate capacity and the pure phase. Distinctive NFS@C@n%CNTs (n = 1, 2, 5, 10) sphere‐shell conductive networks composite cathode materials are constructed creatively, which exhibit superior reversible capacity and rate performance. In detail, the designed NFS@C@2%CNTs cathode delivers an initial discharge capacity of 95.9 mAh g−1 at 0.05 C and up to 60 mAh g−1 at a high rate of 10 C. The full NFS@C@2%CNTs//HC cell delivers a practical operating voltage of 3.5 V and mass‐energy density of 140 Wh kg−1 at 0.1 C, and it can also retain 67.37 mAh g−1 with a capacity retention rate of 96.4% after 200 cycles at 2 C. On the other hand, a novel combination reaction mechanism is first revealed for forming NFS from the mixtures of Na2Fe(SO4)2·nH2O (n = 2, 4) and FeSO4·H2O during the sintering process. The inspiring results would provide a novel perspective to synthesize high‐performance alluaudite sulfate and analogs by aqueous methods.
Octylammonium Iodide Induced In‐situ Healing at “perovskite/Carbon” Interface to Achieve 85% RH‐moisture Stable, Hole‐Conductor‐Free Perovskite Solar Cells with Power Conversion Efficiency >19%
Authors: Lin Siyuan , Fang Zhenxing , Ma Jiao , Guo De'en , Yu Xiaohan , Xie Haipeng , Fang Mei , Zhang Dou , Zhou Kechao , Gao Yongli , Zhou Conghua 
Published: September 2023

Abstract“Perovskite/carbon” interface is a bottle‐neck for hole‐conductor‐free, carbon‐electrode basing perovskite solar cells due to the energy mismatch and concentrated defects. In this article, in‐situ healing strategy is proposed by doping octylammonium iodide into carbon paste that used to prepare carbon‐electrode on perovskite layer. This strategy is found to strengthen interfacial contact and reduce interfacial defects on one hand, and slightly elevate the work function of the carbon‐electrode on other hand. Due to this effect, charge extraction is accelerated, while recombination is obviously reduced. Accordingly, power conversion efficiency of the hole‐conductor‐free, planar perovskite solar cells is upgraded by ≈50%, or from 11.65 (± 1.59) % to 17.97 (± 0.32) % (AM1.5G, 100 mW cm−2). The optimized device shows efficiency of 19.42% and open‐circuit voltage of 1.11 V. Meanwhile, moisture‐stability is tested by keeping the unsealed devices in closed chamber with relative humidity of 85%. The “in‐situ healing” strategy helps to obtain T80 time of >450 h for the carbon‐electrode basing devices, which is four times of the reference ones. Thus, a kind of “internal encapsulation effect” has also been reached. The “in situ healing” strategy facilitates the fabrication of efficient and stable hole‐conductor‐free devices basing on carbon‐electrode.
Near Quantitative Ligation Results in Resistance of DNA Origami Against Nuclease and Cell Lysate
Authors: Krishnamurthy Kirankumar , Rajendran Arivazhagan , Nakata Eiji , Morii Takashi 
Published: September 2023

AbstractThere have been limited efforts to ligate the staple nicks in DNA origami which is crucial for their stability against thermal and mechanical treatments, and chemical and biological environments. Here, two near quantitative ligation methods are demonstrated for the native backbone linkage at the nicks in origami: i) a cosolvent dimethyl sulfoxide (DMSO)‐assisted enzymatic ligation and ii) enzyme‐free chemical ligation by CNBr. Both methods achieved over 90% ligation in 2D origami, only CNBr‐method resulted in ≈80% ligation in 3D origami, while the enzyme‐alone yielded 31–55% (2D) or 22–36% (3D) ligation. Only CNBr‐method worked efficiently for 3D origami. The CNBr‐mediated reaction is completed within 5 min, while DMSO‐method took overnight. Ligation by these methods improved the structural stability up to 30 °C, stability during the electrophoresis and subsequent extraction, and against nuclease and cell lysate. These methods are straightforward, non‐tedious, and superior in terms of cost, reaction time, and efficiency.
Precise review of a male's infertility assessment from a men's health specialist prospective
Authors: Khalafalla Kareim , Ammar Laila , Wang Run 
Published: September 2023

AbstractInfertility is a pervasive issue affecting a considerable proportion of couples in their reproductive years, with a projected 10%–15% prevalence. It is characterized by the incapability to achieve conception following a year of consistent, unprotected intercourse, and its far‐reaching consequences can take a profound emotional, psychological, and social toll on couples, inducing feelings of melancholy, exasperation, and anxiety. The appraisal of infertile couples' cases is a multifaceted and daunting process, necessitating a holistic understanding of the intricate underlying factors contributing to their infertility. Consequently, an individualized evaluation should be conducted, considering diverse parameters, such as the couple's medical history, age, infertility duration, and other relevant criteria. This paper will provide an in‐depth overview of the current approaches utilized in the evaluation of men with infertility, including the commonly employed diagnostic tools and procedures. Enhancing our comprehension of infertility assessment and management holds the promise of helping couples achieve their ultimate desire of conceiving and enriching their overall quality of life.
Antimicrobial susceptibility profile of oral and rectal microbiota of non‐human primate species in Ghana: A threat to human health
Authors: Adade Eugene , Tawiah Patrick Ofori , Roos Christian , Chuma Idrissa Shomari , Lubinza Clara Clavery , Mfinanga Sayoki Godfrey Mrinde , Knauf Sascha , Sylverken Augustina Angelina 
Published: September 2023

AbstractBackgroundThe potential for the transfer of zoonotic diseases, including bacteria between human and non‐human primates (NHPs), is expected to rise. It is posited that NHPs that live in close contact with humans serve as sentinels and reservoirs for antibiotic‐resistant bacteria.ObjectivesThe objective was to characterize the oral and rectal bacteria in Ghanaian NHPs and profile the antimicrobial susceptibility of the isolated bacteria.MethodsOral and rectal swabs were obtained from 40 immobilized wild and captive NHPs from 7 locations in Ghana. Standard bacteriological procedures were used in the isolation, preliminary identification, automated characterization and antimicrobial susceptibility test (AST) of bacteria using the Vitek 2 Compact system.ResultsGram‐negative bacteria dominated isolates from the rectal swabs (n = 76, 85.4%), whereas Gram‐positive bacteria were more common in the oral swabs (n = 41, 82%). Staphylococcus haemolyticus (n = 7, 14%) was the most occurring bacterial species isolated from the oral swabs, whereas Escherichia coli (n = 32, 36%) dominated bacteria isolates from rectal swabs. Enterobacter spp. had the highest (39%) average phenotypic resistance to antimicrobials that were used for AST, whereas a trend of high resistance was recorded against norfloxacin, Ampicillin and Tetracycline in Gram‐negative bacteria. Similarly, among Gram‐positive bacteria, Staphylococcus spp. had the highest (25%) average phenotypic resistance to antimicrobials used for AST, and a trend of high resistance was recorded against penicillin G and oxacillin.ConclusionsThis study has established that apparently healthy NHPs that live in anthropized environments in Ghana harbour zoonotic and antimicrobial resistant bacteria.
Diagnosis of traumatic scleral perforation in a dog using ocular ultrasound and ultrasound biomicroscopy
Authors: Jeong Dajeong , Lee Eunji , Susanti Lina , Kim Hyelin , Seo Kangmoon , Kang Seonmi 
Published: September 2023

AbstractA 10‐year‐old spayed female Maltese dog was presented for hypotony of the right eye (OD) with decreased vision. The dorsomedial region of conjunctiva was partially swollen but the globe remained intact. Slit‐lamp biomicroscopy revealed intraocular haemorrhage, uveitis, and a limbal, corneoconjunctival ulcer near the swollen conjunctiva. During ocular ultrasonography (OUS), the sclera became indented and hypotony occurred, implicating a full‐thickness scleral wound. Ultrasound biomicroscopy (UBM) confirmed a full‐thickness scleral defect, which was surgically apposed. The intraocular pressure normalised and the uveitis subsided post‐operatively. OUS and UBM were helpful in suggesting and definitively diagnosing scleral perforation, leading to accurate treatment and good prognosis.