bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Predictor for Insulin Resistance in Polycystic Ovary Syndrome:
InsuTAG
Authors: Omma Tulay , Gokce Aksanur , Celik Mustafa , Karahan Irfan , Culha Cavit , Gulcelik Nese Ersoz 
Published: March 2023

Background:
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy
among women of reproductive age. PCOS leads to metabolic dysfunction such as dyslipidemia, obesity,
and glucose intolerance based on hyperandrogenemia, hyperinsulinemia, and dysregulated adipokine
secretion.

Objective:
The aim of this study was to investigate whether a new marker, InsuTAG (fasting insulin×fasting
triglycerides) could predict insulin resistance (IR) in patients of PCOS.

Methods:
In this study, retrospective data of 300 female patients diagnosed with PCOS were analyzed.
The relationship between InsuTAG and HOMA-IR, TyG, and TG/HDL-C scores related to insulin resistance
was evaluated. In addition, the distribution of the cases according to the cut-off values was
determined.

Results:
Log-transformed forms of InsuTAG and HOMA-IR, TyG and TG/HDL-C results were positively
correlated, respectively. (r = 0.85, p < 0.001; r = 0.78, p < 0.001; r = 0.72, p < 0.001). Sensitivity,
specificity, positive predictive value and negative predictive values for InsuTAG were calculated
as 85%, 85%, 82% and 88%, respectively.

Conclusions:
This study is the first to compare the InsuTAG, another predictor of insulin resistance,
with other IR markers in women with PCOS. InsuTAG is a novel biomarker based on plasma sampling
of insulin and triglyceride, with minimally invasive, inexpensive and orientally accessible features.
Neuropsychiatric Manifestations in Alzheimer’s Disease Patients: Genetics and Treatment Options
Authors: Singh Arun Kumar , Malviya Rishabha , Prakash Anuj , Verma Swati 
Published: March 2023

Background:Alzheimer's disease (AD) is characterized by neuropsychiatric symptoms (NPS), which cause great misery to those with dementia and those who care for them and may lead to early institutionalization.Objective:The present systematic review aims to discuss the various aspects of Alzheimer’s, including treatment options.Methods:The databases Embase, PubMed, and Web of Science were searched to collect data.Result:Incipient cognitive deterioration is commonly accompanied by these early warning signals of neurocognitive diseases. The neurobiology of NPSs in Alzheimer's disease, as well as particular symptoms, including psychosis, agitation, apathy, sadness, and sleep disorders, will be examined in this review. For NPSs in Alzheimer's disease, clinical trial designs, as well as regulatory issues, were also addressed. A fresh wave of research, however, is helping to push the discipline ahead. For medication development and repurposing, we highlight the most recent results in genetics, neuroimaging, and neurobiology. Even though identifying and treating psychosis in adults with dementia is still a challenging endeavor, new options are coming up that give the field fresh focus and hope.Conclusion:It can be concluded from the complete literature survey that Alzheimer's-related psychosis as well as other symptoms that are not psychotic, have made significant progress in the last decade. These milestones in the development of safer, more effective treatments have been achieved as a consequence of great focus on non-pharmacological interventions like DICE or WHELD; the investigation into ways to improve existing drugs like aripiprazole, risperidone, amisulpride, and Escitalopram for safer precision-based treatment; and the development of a clinical trial program for pimavanserin.
The Discussion of the Influence of Eccentricity Ratio on Lubrication
Characteristics of Fluid Lubricated Bearings
Authors: Yang Xiaodong , Liu Feilin , Liu Hongbo , Zhang Jian , Liu Weifeng , Meng Yue 
Published: March 2023

Abstract:
The operating quality of bearings has also led to higher criteria with the growing status
of the manufacturing industry in social production. The eccentricity ratio of the bearing system is
particularly susceptible to change during operation as a result of the external load, which has a direct
impact on the lubricating properties. On the one hand, a reasonable eccentricity ratio will improve
the bearing's lubrication performance, increase stability, and better meet processing requirements;
on the other hand, it will result in uncontrollable bearing behavior and may even cause the
real world to deviate from the theoretical design model. The study aimed to analyze and discuss the
current findings on the change in bearing eccentricity ratio. More than 100 related articles have
been summarized, and bearing behavior research results, such as lubrication and load-bearing characteristics,
are discussed. This paper discusses the progress of research on the eccentricity ratio
problem of fluid-lubricated bearings, as well as the effect of eccentricity ratio change on bearing
lubrication characteristics for bearings using different lubricating media. Active control measures
to mitigate the negative impact of changing bearing eccentricity ratios are also presented. After analyzing
and summarizing the relevant literature, it has been found that the eccentricity is one of the
important factors affecting the lubrication characteristics of bearings.
DeepFake Detection with Remote Heart Rate Estimation Using 3D Central
Difference Convolution Attention Network
Authors: Feng Xiao , Ma Hua , Sun Yijie 
Published: March 2023

Objective:
As GAN-based deepfakes have become increasingly mature and realistic,
the demand for effective deepfake detectors has become essential. We are inspired by the fact that
normal pulse rhythms present in real-face video can be decreased or even completely interrupted
in a deepfake video; thus, we have introduced a new deepfake detection approach based on remote
heart rate estimation using the 3D Central Difference Convolution Attention Network
(CDCAN).

Methods:
Our proposed fake detector is mainly composed of a 3D CDCAN with an inverse attention
mechanism and LSTM architecture. It utilizes 3D central difference convolution to enhance
the spatiotemporal representation, which can capture rich physiological-related temporal context
by gathering the time difference information. The soft attention mechanism is to focus on the skin
region of interest, while the inverse attention mechanism is to further denoise rPPG signals.

Results:
The performance of our approach is evaluated on the two latest Celeb-DF and DFDC datasets,
for which the experiment results show that our proposed approach achieves an accuracy of
99.5% and 97.4%, respectively.

Conclusion:
Our approach outperforms the state-of-art methods and proves the effectiveness of
our DeepFake detector.
Subarray 4×4 untuk Antena MIMO 5G dengan Elemen yang Menerapkan Teknik Parasitic
Authors: Fitri Amillia  , Eko Setijadi  , Gamantyo Hendrantoro  
Published: March 2023

Multiple-input multiple-output (MIMO) merupakan sistem komunikasi nirkabel yang menggunakan banyak antena di sisi pemancar maupun penerima. Sistem ini dapat meningkatkan kualitas komunikasi nirkabel pada jaringan teknologi 5G. Teknologi 5G memiliki kecepatan data yang sangat tinggi dan tunda (delay) yang sangat rendah. Jaringan 5G di Indonesia menggunakan frekuensi menengah, yaitu pada pita frekensi 3,5 GHz. Antena merupakan perangkat yang penting di jaringan nirkabel sistem MIMO. Oleh karena itu, penelitian ini mengusulkan perancangan elemen tunggal menggunakan teknik parasitic untuk memperlebar lebar bidang (bandwidth) guna memenuhi kebutuhan antena MIMO dan perancangan antena subarray 4×4 untuk MIMO 5G. Metode yang dilakukan pada penelitian ini diawali dengan menentukan spesifikasi target antena, kemudian melakukan perancangan elemen tunggal dengan parasitic patch. Penggunaan teknik parasitic patch pada elemen antena bertujuan untuk memperlebar bandwidth supaya memenuhi spesifikasi target. Frekuensi resonansi antena mikrostrip dipengaruhi oleh penambahan jumlah parasitic patch. Banyaknya frekuensi resonansi yang timbul menghasilkan bandwidth yang lebar. Kemudian, elemen tunggal dengan parasitic patch disusun menjadi subarray 4×4. Semua elemen disusun dalam satu substrat yang sama dengan jarak antarelemen dari titik pencatuan satu ke titik pencatuan lainnya sebesar 64,28 mm atau 0,75λ. Desain subarray sudah memenuhi target spesifikasi antena jika elemen subarray sudah mempunyai fractional bandwidth lebih dari 20% dan mutual coupling kurang dari −20 dB. Bahan yang digunakan dalam desain dan fabrikasi antena adalah substrat FR-4 (epoxy) dengan konstanta dielektrik (Ɛr) 4,3 dan ketebalan substrat (h) 1,6 mm. Hasil menunjukkan bahwa diperoleh bandwidth sebesar 735 MHz atau fractional bandwidth sebesar 20,35%, return loss 14,65 dB, mutual coupling 30,05 dB, dan gain 16,86 dB. Dengan demikian, subarray 4×4 untuk antena MIMO yang dirancang sudah memenuhi spesifikasi yang diinginkan.
Study of the Effect of Magnetic Abrasive Finishing on the Material Removal of AA1100 Aluminum Alloy
Authors: Majeed Mariam , H.Khadum Ali , Al-Zubaidi Salah 
Published: March 2023

This study evaluates the performance of magnetic abrasive finishing (MAF) of aluminum alloy in terms of achieving materials removal (MR). A vertical milling machine is used to perform the finishing process using a developed MAF unit that consists of an inductor made out of a 150 mm long and 20 mm diameter iron core wound with 1500 turns and 0.5 mm copper wire. The commutator and magnetic pole are attached at the top and bottom of the inductor, respectively. The required current is supplied using a DC power supply. The South Pole workpiece is a 100×50×3 mm3 plate of AA 1100 aluminum alloy, whereas the magnetic pole represented the North Pole. Pole rotational speed, applied current, and abrasive finishing time was selected as input parameters of the MAF with three-level of (270, 600. 930 rpm; 0.5, 1, 1.5 Amp; 6,9,12 min). The L9 orthogonal array of the Taguchi method was utilized to examine the impact of each independent input. The obtained results clarify that applied current was the most effective factor in terms of its contribution (63.16%) in the produced MR, followed by time finishing and rotational speed.
Exploring athletic trainers’ experience and perceptions associated with a multifaceted approach to concussion management
Authors: Stavitz James 
Published: March 2023

Aim: To explore high school athletic trainers’ experience with, and perceptions of, a multifaceted approach to concussion management. Participants: A total of 20 high school athletic trainers that are certified and licensed to practice (if their state requires a license to practice) participated in this study. Materials & methods: A general qualitative design with descriptive coding and saturation was met at 20 interviews. Results: Lack of standardization allows assessment, referral and return-to-play experiences to vary significantly; referral experiences vary pending upon athletic trainers ability to refer to a trusted and responsive physician; barriers include clearances from unqualified physicians; pressure from coaches, parents and students to return students to play; benefits include increased knowledge and awareness resulting in more effective care for students. Conclusion: Athletic trainers have varying experiences and perceptions regarding their approaches to concussion management. However, there were many notable similarities in the experiences, pressures, barriers and benefits when applying their concussion protocol.
interpretación de la contradicción de tesis 293/2011: jurisprudencia inconvencional
Authors: Uscanga Barradas Abril 
Published: February 2023

En este análisis se tratan los dilemas y el rompimiento del paradigma que nos permitan comprender al derecho como una disciplina viva, en movimiento, dinámica, que no siempre encuentra sus respuestas en las leyes, por lo que la resolución de una litis o controversia implica un gran reto para los operadores del derecho: es ahí donde los juristas tienen que aplicar todo su conocimiento, habilidades, competencias, creatividad e incluso imaginación.
The Main Statements of the Consensus “Maastricht-VI” (2022) on the Diagnostics and Treatment of <i>Helicobacter pylori</i> Infection
Authors: Sheptulin A. A. 
Published: March 2023

Aim: to present an analysis of the published materials of the consensus “Maastricht-VI” on the management of patients with Helicobacter pylori (H. рylori) infection.Key points. The content of the new consensus “Maastricht-VI” largely corresponds to that of the previous “Maastricht-V” consensus. This refers to the methods of diagnostics of this infection, indications for eradication. The introduction of eradication schemes of the 3rd and 4th lines, as well as a double scheme with increased doses of proton pump inhibitors (PPI) and amoxicillin can be considered new. The important role of measures that increase the effectiveness of eradication (14-day duration of the course, increasing the dose of PPI, the use of probiotics) is emphasized.Conclusion. The publication of materials of the new consensus “Maastricht-VI” will contribute to improving the results of H. рylori eradication therapy.
Gut Microbiota and its Metabolites in Pathogenesis of NAFLD
Authors: Reshetova M. S. , Zolnikova O. Yu. , Ivashkin V. T. , Ivashkin K. V. , Appolonova S. A. , Lapina T. L. 
Published: March 2023

Aim: to provide information on the results of recent scientific research in the field of non-alcoholic fatty liver disease (NAFLD) metabolomic profiling.Key points. Metabolites of microbial origin are important biological molecules involved in many specific reactions of the human body. This literature review presents the results of recent studies in the field of metabolomics in patients with NAFLD. A more detailed understanding of the role of individual metabolites or their combinations in the NAFLD pathogenesis will allow us to determine the vector of further diagnostic and therapeutic approaches for this nosology. The research results of the probiotics effect on the levels of certain metabolites are currently being discussed.Conclusion. New research data in the field of studying the human metabolomic profile are presented. The results allow us to summarize the effects of microbial agents and their metabolites in the formation of changes in the liver parenchyma in the context of NAFLD. Changes in the level of endogenous ethanol, secondary bile acids, aromatic amino acids, branched chain amino acids, etc. have been described. Correlation between metabolites and certain bacterial strains has been established. A correlation between the ratio of bacteria types and clinical/laboratory parameters was noted in patients taking prebiotics.
Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes
Authors: Heise Tim , DeVries J. Hans , Urva Shweta , Li Jing , Pratt Edward J. , Thomas Melissa K. , Mather Kieren J. , Karanikas Chrisanthi A. , Dunn Julia , Haupt Axel , Milicevic Zvonko , Coskun Tamer 
Published: March 2023

OBJECTIVE
To evaluate the effects of tirzepatide on body composition, appetite, and energy intake to address the potential mechanisms involved in body weight loss with tirzepatide.

RESEARCH DESIGN AND METHODS
In a secondary analysis of a randomized, double-blind, parallel-arm study, the effects of tirzepatide 15 mg (N = 45), semaglutide 1 mg (N = 44), and placebo (N = 28) on body weight and composition, appetite, and energy intake were assessed at baseline and week 28.

RESULTS
Tirzepatide treatment demonstrated significant reductions in body weight compared with placebo and semaglutide, resulting in greater fat mass reduction. Tirzepatide and semaglutide significantly reduced appetite versus placebo. Appetite scores and energy intake reductions did not differ between tirzepatide and semaglutide.

CONCLUSIONS
Differences in energy intake during ad libitum lunch were not sufficient to explain the different weight outcomes. Further evaluation is needed to assess mechanistic differences related to tirzepatide actions on 24-h energy intake, substrate utilization, and energy expenditure.
Long-term follow-up of 96 patients younger than age 25 with 119 primary cemented total hip arthroplasties
Authors: Özdemir Erim , Kuijpers Martijn F L , Schreurs B Willem , Rijnen Wim H C 
Published: March 2023

Background and purpose: Long-term follow-up of young patients following cemented primary THA is scarce. Therefore, we analyzed the survival of all consecutive primary THAs in patients under 25 years performed at our institute.Patients and methods: All primary THAs performed in patients younger than 25 years in our tertiary care institute between 1988 and 2015 were included (n = 119). Cemented fixation was used in all patients. In the case of acetabular bone deficiencies, reconstruction was performed using impaction bone grafting (IBG). We used Kaplan–Meier analysis to determine the survival of the primary THA with endpoints revision for any reason and aseptic loosening.Results: The mean age at the primary THA was 20 years. The most prevalent diagnosis was avascular necrosis (31%). The mean follow-up of the primary THA was 11 years (range 0–32). 2 patients (2 hips) were lost to follow-up. 16 revisions were registered. The survival of any component for endpoint revision for any reason was estimated at 92% (95% confidence interval [CI] 84–96) and 81% (CI 67–90) at 10- and 15-year follow-up, respectively. The survival of any component for endpoint revision for aseptic loosening was 99% (CI 93–100) and 88% (CI 71–95) at 10 and 15 years, respectively. 3 hips were revised due to infection.Conclusion: Favorable long-term outcomes of primary THA in very young patients can be obtained using cemented fixation and IBG.
FERMENTASI ENZIMATIS KOPI ROBUSTA (Coffea robusta) UNTUK PRODUKSI KOPI LUWAK KOPI SEHAT BERKELANJUTAN MELALUI PEMBELAJARAN JELAJAH ALAM SEKITAR (JAS)
Authors: Elvita Sari Desi 
Published: March 2023

Abstrak: Pendekatan pembelajaran JAS adalah salah satu inovasi pendekatan pembelajaran Biologi dan merupakan kajian ilmu lain yang bercirikan memanfaatkan lingkungan sekitar dan simulasinya sebagai sumber belajar melalui kerja ilmiah, serta diikuti pelaksanaan belajar yang berpusat pada peserta didik. Kopi luwak merupakan kopi yang menggunakan biji kopi yang telah diproses dari system pencemaran hewan luwak/musang. Biji kopi ini berada di dalam saluran pencernaan luwak selama 12 jam diyakini memiliki rasa yang berbeda setelah dimakan dan melewati saluran pencernaan luwak. Bioteknologi kopi luwak dapat dilakukan dengan proses meniru fermentasi enzimatis seperti yang terjadi dalam perut luwak. Jenis luwak bulan saat memakan biji kopi pada malam hari bisa menghasilkan 1 kg kopi luwak. dan jenis luwak pandan bisa menghasilkan 5 kg kopi luwak.
PENGARUH STRATEGI PEMBELAJARAN MODEL STD DAN TGT BERDASARKAN PENGELOMPOKAN KEMAMPUAN AKADEMIK TINGGI DAN RENDAH TERHADAP BIOLOGI KOGNITIF
Authors: Noviawan *Dwi , Karwono Karwono , Santoso Handoko 
Published: March 2023

Riset di SMAN 5 Metro Tanggal 14 Juni - 30 September 2017. X1 (STAD dan TGT), X2 (Kemampuan Akademik Tinggi dan Rendah), Y (Biologi Kognitif). Eksperimen Faktorial 22. Sampel STAD 28, TGT 28 berdasarkan kemampuan akademik tinggi dan rendah. Pengambilan sampel acak bertingkat. Dokumentasi dan tes. Anova 2 jalur, uji t independent dan berpasangan.
Tujuan: 1) membedakan biologi kognitif STAD dan TGT. Menunjukan hasil 0.689 > 0.05 tidak ada perbedaan dikeduanya. 2) membedakan biologi kognitif dari kemampuan tinggi dan rendahnya akademik. Hasilnya 0.891 > 0.05, artinya tidak berbeda. 3) berdasarkan akademik tinggi, digunakan model STAD dan TGT, membedakan biologi kognitifnya. Hasilnya Sig 0,854 (p > 0,05) artinya tidak berbeda. 4) berdasarkan kelompok akademik rendah, digunakan model pembelajaran STAD dan TGT, membedakan biologi kognitif. Perhitungan SPSS nilainya Sig 0,833 (p > 0,05) berarti tidak berbeda. 5) mengetahui interaksi STAD dan TGT berdasarkan kemampuan akademik tinggi dan rendah terhadap biologi kognitif. Uji ANOVA 2 arah hasil X1 kepada Y Sig. 0.205 > 0.05 interaksi X2 kepada Y Sig 0.233 > 0.05 intraksinya tidak signifikan. Interaksi X1 dan X2 terhadap Y Sig. 0.443 > 0.05 interaksinya tidak signifikan.
Water beetles (Coleoptera: Haliplidae, Dytiscidae, Helophoridae, Hydrophilidae, Hydraenidae, Elmidae, Psephenidae, Scirtidae) of the Slavíč river basin, Czech Republic
Authors: Straka Michal , Kroča Jiří 
Published: March 2023

Abstract
Twenty-three sites within the Slavíč river basin (Silesia, Czech Republic) were surveyed to obtain up-to-date information on water beetles in the area. In total, 46 species comprising eight families were recorded. Significant findings included Ochthebius melanescens Dalla Torre, 1877, Hydrocyphon deflexicollis (Müller, 1821) (both endangered), Hydraena morio Kiesenwetter, 1849, Eubria palustris (Germar, 1818) (both vulnerable), Hydraena minutissima Stephens, 1829 (near threatened) and Elodes pseudominutus Klausnitzer, 1971 (data deficient). The Slavíč water beetle assemblage consisted mainly of typical rheophilic species, many characteristic for cold, mountainous waters, the most common beetles recorded being representatives of the families Elmidae and Hydraenidae. The species spectrum was significantly enriched by species found in non-riverine habitats along the Slavíč River floodplain (e.g. springs, wetlands and ponds), with representatives of the families Dytiscidae, Haliplidae and Hydrophilidae dominating.
Subfamily Phlebotominae (Psychodidae, Diptera) of the United Arab Emirates – some new faunistic data
Authors: Ježek Jan , Tkoč Michal , Oboňa Jozef , Manko Peter , van Harten Antonius 
Published: March 2023

Abstract
Biting midges (Phlebotominae) are medically important vectors of human and veterinary disease-causing agents. This study presents the results of the field research of arthropods of A. van Harten in the United Arab Emirates (UAE) during the period of approximately 2005 – 2007 at a high number of localities (15 are mentioned here, with 9 species collected incl. five confirmed; 4 spp. are new for the fauna of the UAE: Phlebotomus (Phlebotomus) papatasi (Scopoli, 1786), Sergentomyia (Parrotomyia) baghdadis (Adler & Theodor, 1929), S. (Sergentomyia) schwetzi Adler, Theodor & Parrot, 1929, S. (Grassomyia) squamipleuris Newstead, 1912).
Institutions Strengthening the Position of the Injured Party of the Offence of Failure to Pay Alimony under Section 196 of the Czech Criminal Code and in Selected European Legal Regulations
Authors: Rabinská Ivana 
Published: March 2023

Summary
The offence of failure to pay alimony under section 196 is one of the most frequent offences in the Czech Republic. Since the protected interest is the right to support and maintain and the most common is the duty of parents towards their children, it is a very serious illegal activity that significantly endangers children and has a negative impact on their development, both health and social. In recent years, Czech legislators have focused on this issue and adopted institutes that strengthen the position of the injured party in these cases. Any kind of sanction has proved to be an ineffective tool for enforcing the delinquent alimony, so it has been necessary to ensure that it can be enforced by other means. Therefore, the legislators broadened the definition of the injured party in criminal proceedings and introduced the so-called substitute alimony. It is also interesting to look into foreign legal regulations and compare selected institutes.