bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of the relationship between sleep-related parameters and metabolic syndrome (MetS) among youths in the Southeast of Iran
Authors: Kazemi Majid , Khalili Parvin , Kazemi Mahsa , Hasani Hadi , Sadeghi Marjan , Jamali Zahra 
Published: May 2023

Abstract
Background and aim
There are few studies and inconsistent findings on the role of sleep-related parameters in the development of metabolic syndrome (MetS) among youths. In this study, we aim to investigate the relationship between sleep-related parameters and MetS among youths in a large sample size in Rafsanjan, a region in the southeast of Iran.

Methods
The current cross-sectional study was performed on 3,006 young adults aged 15–35, who registered for Rafsanjan Youth Cohort Study (RYCS), as part of Rafsanjan Cohort Study (RCS)). In fact, RCS is a branch of the prospective epidemiological research studies in Iran (PERSIAN). In the present study, we included 2,867 youths after excluding some subjects with missing information on MetS components. MetS was diagnosed based on Adult Treatment Panel III (ATP III) criteria. Besides, data on sleep-related parameters were collected by self-report questionnaires.

Results
The overall prevalence of MetS was 7.74% among the participants. In addition, bedtime, wake time, napping, night shift work, and sleep duration per night and day had no association with the higher odds of having MetS. In contrast, long sleep duration at night was associated with the lower odds of high waist circumference (WC) (OR: 0.82,95% CI :0.67–0.99).

Conclusion
In the present study, long sleep duration at night was associated with lower odds of central obesity. However, more longitudinal studies with the objective measurement of sleep-related parameters are needed to verify the associations reported in the current study.
Acute encephalomyelitis in a 52-year-old male post messenger ribonucleic acid severe acute respiratory syndrome coronavirus 2 vaccination: a case report
Authors: Alebna Pamela Lamisi , Shahid Muhammad Ahmad , Brannan Timothy , Shen Ting , Marian Valentin 
Published: May 2023

Abstract
Background
Acute disseminated encephalomyelitis is a well-known, but rare, side effect of some vaccines, or symptom following a febrile illness.

Case
A 69-year-old, otherwise healthy Hispanic male presented with acute fever, confusion, and later progressive weakness after receiving the first dose of the mRNA-1273 (Moderna) severe acute respiratory syndrome coronavirus 2 vaccine. Considering the progressive deterioration of the patient, despite being on multiple immunosuppressive agents, a brain biopsy was obtained, which revealed nonspecific meningoencephalitis.

Conclusion
In this case, we highlight the need for a regulatory framework to assist clinicians and patients with coverage of treatment for acute disseminated encephalomyelitis. The use of intravenous immunoglobulin in conjunction with glucocorticoids seems to be an effective treatment option.
Seaweed extracts as biological control of aflatoxins produced by Aspergillus parasiticus and Aspergillus flavus
Authors: Farghl Abla A. M. , El-Sheekh Mostafa M. , El-Shahir Amany A. 
Published: May 2023

Abstract
Background
Mycotoxins are secondary metabolites made by a variety of molds and fungi. They contaminate a lot of food products and local crops during pre- and post-harvesting under favorable conditions like high temperature and moisture. Aspergillus species are the most common fungi that contaminate food and produce biochemicals known as mycotoxins. Aflatoxins (AFB1, AFB2, AFG1, and AFG2) are the major mycotoxins produced by A. flavus and A. parasiticus that harm animal and human health. These fungi are controlled by chemical fungicides, but these are harmful to the environment. The aim of this study was to determine whether the aflatoxigenic fungi can be exterminated only by marine algal extracts or not.

Results
The findings showed that the tested seaweed extracts inhibited fungal growth and aflatoxins production to varying degrees. The maximum antifungal activity was recorded in Halimeda opuntia extract against A. parasiticus-24 and A. flavus-18 and Turbunaria decurrens extract against A. flavus-18 (with an inhibition percentage of 77.78%), followed by Jania rubens extract against A. parasiticus-16 with inhibition percentage 75.88% compared to the control. Aqueous extract of H. opuntia effectively eliminated aflatoxins (B1, B2, G1, and G2) in A. parasiticus-16 and A. parasiticus-24. T. decurrens extract could detoxify 100% of aflatoxins in three isolates of A. parasiticus. J. rubens extract eliminated aflatoxins in A. parasiticus-15 and A. parasiticus-16 compared to their normal production using high-performance liquid chromatography.

Conclusions
According to this study, the macroalgal species with numerous distinctive antifungal properties constituents significantly inhibited the growth and production of aflatoxin in A. parasiticus and A. flavus isolates. The findings supported the use of macroalgae as a biological control agent against fungi and their toxins.
Assessment of endovascular embolization of cerebral arterio-venous malformations in vertebrobasilar domain
Authors: Eltantawi Mohamed Abdelhalim , Monzer Mahmoud Abdel-Moety , Sobh Khaled Mohamed , Yaseen AbdEllahNazeer , Ahmed Mahmoud Galal 
Published: May 2023

Abstract
Background
Endovascular approaches have been widely applied in patients with brain arterio-venous malformations (AVM). However, little is known regarding the risk factors for complications or predictors of procedure success. Herein, we report our experience regarding the outcomes of endovascular embolization of posterior fossa AVM, focusing on how angioarchitectural and hemodynamic characteristics of the AVM affect the post-intervention outcomes. 17 patients diagnosed with posterior cranial fossa AVM were enrolled and scheduled for endovascular interventions by Onyx or Histoacryl.

Results
Most patients had a single session (58.8%), while 29.4% had two sessions, 11.7% had three sessions. Total nidus obliteration was achieved in 52.9% of cases, while 35.3% and 11.8% of them had subtotal and partial occlusion, respectively. Postprocedural hematoma was encountered in 17.6% of cases. All preprocedural demographic characteristics did not have a significant impact on occlusion outcomes. However, some angioarchitecture criteria were associated with partial occlusion including large size, superficial or mixed drainage. No significant association was noted between patients criteria and the incidence of complications.

Conclusion
Endovascular interventions could be curative for brain AVM, with an accepted periprocedural morbidity rate. Proper knowledge of the angioarchitectural characteristics of these lesions could help us to predict lesions that carry high risk for complications or high chance for cure.
Superbugs: a constraint to achieving the sustainable development goals
Authors: Mohsin Shahriar , Amin Mohammad Nurul 
Published: May 2023

Abstract
Background
Antimicrobial resistance has already emerged as a major concern not only for public health but also for global economy. It causes a multifaceted crisis in development and growth by increasing the number of infections and deaths. Sustainable Development Goals are in place to ensure that development and growth are continual, as well as to end poverty, protect the environment, and promote peace and prosperity. In this review we tried to highlight the reasons for the prevalence of superbugs as well as their multifaceted impact on healthcare, and demonstrate potential ways to combat them and incorporate them into international policymaking processes.

Main body of the abstract
The literature review included articles from MEDLINE, EMBASE, Scopus, and PubMed published till the end of the year 2022 using keyword searches. Two hundred and forty-three research articles, review papers and studies written in English language evaluating the impact of Antimicrobial resistance (AMR) on patient, society and economy published until end of the year 2022 were included.

Short conclusion
This review highlighted the significant impact of antimicrobial resistance (AMR) on the Sustainable Development Goals (SDGs) and was able to identify at least five SDGs that are linked to healthcare. The emergence of superbugs results in increased expenditure, which has serious consequences for the global economy, particularly in developing countries where infectious diseases are prevalent. The overuse and misuse of antibiotics, as well as poor infection control practices, are identified as primary drivers of superbug emergence. However, implementing strategies such as rational antibiotic use, effective infection control practices, and developing new antibiotics and alternative therapies can mitigate the adverse effects of AMR and contribute to achieving the SDGs. It is essential to integrate AMR strategies into national development plans and improve cross-sectoral collaboration among stakeholders to combat superbugs effectively.
A case of multidrug-resistant miliary tuberculosis mimicking lymphoma: a matter of life or death
Authors: Gursoy Vildan , Ozkalemkas Fahir , Dilektaslı Aslı Gorek , Demirdogen Ezgi , Ozkocaman Vildan , Pinar Ibrahim Ethem , Ener Beyza , Akalin Halis , Kazak Esra , Ali Rıdvan 
Published: May 2023

Abstract
Background
Tuberculosis (TB) is a systemic infectious disease that is caused by Mycobacterium tuberculosis and which can affect many tissues and organs. Despite the development of curative and preventive therapies in recent years, TB continues to be a serious health problem, in the developing countries in particular.

Case presentation
In this case report, an extraordinary case of miliary tuberculosis with unexplained fever, joint pain, weight loss, pancytopenia, lymphadenopathy and splenomegaly, who was clinically suspected of lymphoma and successfully treated with a multidisciplinary approach without any complications, was presented. This case has been reported not because it is a rare case, but to raise awareness. It is a case, where early diagnosis and initiation of treatment early, as well as an individualized and multidisciplinary treatment approach emerged as the most important factors resulting in an improvement prognosis.

Conclusion
Extrapulmonary TB, if with lymph node involvement in particular, can easily mimic lymphoma. Imaging methods and clinical findings may be insufficient to distinguish these two conditions at the time of diagnosis. In such a case, it will be beneficial for the patient to proceed with an experienced team in the management of the patient.
Assessment of external radiation dose rate after 18FDG-PET/CT examination
Authors: Aldousari Hanan , Abuhadi Nouf , Izz Mariam , Alshammari Thekra , Ali Zainab , Aldaas Razan , Bakry Abdoelrahman Hassan Ali , Abukonna Ahmed , Esmail Abdulredha 
Published: May 2023

Abstract
Background
F-18 FDG (fluorodeoxyglucose) PET/CT procedures are one of the most growing studies used for patient management in oncology, cardiology, neurology, and other indications, in which the challenges meet both patients and clinicians, especially when we are looking for the presence/absence of disease progression and cure. This study was conducted to assess the external radiation dose after 18FDG-PET/CT examination. In total, 117 patients were enrolled in the study. Radiation exposure was measured using a calibrated RadEye SPRD-ER personal radiation detector. The measurements were taken at 0, 30, 100, 150, and 200 cm distance from the patient. The time of measurement was immediately post-injection, 30 min, 60 min after injection, and at the time of releasing the patient.

Results
The result showed that the mean radiation equivalent dose rate at 0 min/0 cm was 414 µSv/h, at 30 min/30 cm was 99.7 µSv/h, and 60 min/100 cm was 18.3 µSv/h. The radiation doses at different distances (0, 30, 100, 150, and 200 cm) were 160.9 µSv/h, 70.9 µSv/h, 12.4 µSv/h, 7 µSv/h, and 3.7 µSv/h, respectively.

Conclusion
In conclusion, the patient can be safely released after 2 h of injection in (18F-FDG) PET/CT and the radiation dose can be limited by increasing distance from the radiation source and also instructing them to drink much more water to enhance the process of excretions. The dose rates are low in this study; if the staff interact with multiple patients, they will not approach exposure limits. Similarly, dose rates are so low at patient release that family will not receive doses above regulatory limits.
MXene sensors based on optical and electrical sensing signals: from biological, chemical, and physical sensing to emerging intelligent and bionic devices
Authors: Wu Leiming , Yuan Xixi , Tang Yuxuan , Wageh S. , Al-Hartomy Omar A. , Al-Sehemi Abdullah G. , Yang Jun , Xiang Yuanjiang , Zhang Han , Qin Yuwen 
Published: May 2023

AbstractSensing devices are key nodes for information detection, processing, and conversion and are widely applied in different fields such as industrial production, environmental monitoring, and defense. However, increasing demand of these devices has complicated the application scenarios and diversified the detection targets thereby promoting the continuous development of sensing materials and detection methods. In recent years, Tin+1CnTx (n = 1, 2, 3) MXenes with outstanding optical, electrical, thermal, and mechanical properties have been developed as ideal candidates of sensing materials to apply in physical, chemical, and biological sensing fields. In this review, depending on optical and electrical sensing signals, we systematically summarize the application of Tin+1CnTx in nine categories of sensors such as strain, gas, and fluorescence sensors. The excellent sensing properties of Tin+1CnTx allow its further development in emerging intelligent and bionic devices, including smart flexible devices, bionic E-skin, neural network coding and learning, bionic soft robot, as well as intelligent artificial eardrum, which are all discussed briefly in this review. Finally, we present a positive outlook on the potential future challenges and perspectives of MXene-based sensors. MXenes have shown a vigorous development momentum in sensing applications and can drive the development of an increasing number of new technologies.
Public policies and conservation plans of historic urban landscapes under the sustainable heritage tourism milieu: discussions on the equilibrium model on Kulangsu Island, UNESCO World Heritage site
Authors: Zhao Long , Li Yuan , Zhang Na , Zhang Zhenxin 
Published: May 2023

Abstract
Purpose
The tensions and threats in historic urban landscapes brought about by heritage tourism are still regional, global, general, and dynamic issues. For Kulangsu, there is an obvious problem in the connection between the current conservation plan and public policy. To a large extent, public policy cannot effectively, specifically, and flexibly respond to the dynamic problems in the implementation of the conservation plan, which seems insufficient concerning the effect of these conservation plans and public policies on promoting the adaptive reuse and sustainable tourism of the historic urban in Kulangsu heritage sites. Thus, giving more consideration to the combination of public policies and conservation plans of historic urban landscapes under the heritage tourism milieu, ensuring a balanced, sustainable, and integrated development pattern still calls for new discussions in achieving good performance of sustainable heritage tourism. This study conceptually discusses the equilibrium model of historic urban landscapes with a range of strategies under a sustainable heritage tourism background and responds to the synthetic contradiction of the imbalances among public policy, conservation plans, and development practices.

Design/methodology/approach
The study is based on a range of prepared desktop studies (public policy studies, conservation plans), field surveys, participant observations, and randomised interviews to respond to the insufficiency of the current heritage practices.

Findings
This study discusses the equilibrium model of sustainable heritage tourism at heritage sites. It takes Kulangsu Island, a UNESCO World Heritage site in Southeast China, as an example to discuss the equilibrium model, which encompasses a convergent parallel framework and three dimensions concerning heritage management and policymaking. The equilibrium model of historic urban landscapes is a dynamic framework that integrates social, economic, environmental, and cultural concerns into a holistic collaborative framework under a sustainable heritage tourism background.

Originality/value
In line with the requirements of the Historic Urban Landscape (HUL) approach and general principles in support of sustainable urban heritage management promoted by UNESCO and ICOMOS, the study points out the peculiarities and potential of the equilibrium mode in solving the current challenges of historic urban landscapes for sustainable heritage tourism. Finding ways of linking policymaking, conservation, development, heritage tourism, and different interest groups to a holistic framework can stimulate effective means and management mechanisms for the complicated and changeable issues of sustainable heritage tourism.
Modeling and simulation of short channel length effect in open drain MOSFET THz detectors
Authors: Mohamed Yasmeen A. , Ibrahim Nihal Y. , El Zayat Mohamed Y. F. , Elnahwy Salah E. A. 
Published: May 2023

AbstractTHz radiation detection using FET devices has attracted increasing attention lately. In this paper, we further study a simulated model of FET rectification detection in short channel length. To achieve this, both physics-based analytic model and a detailed TCAD simulation were contacted and compared. The analytical model provided detailed dependence of the response on the channel length below the extension length of the radiation. However, the simulation results were validated by comparison with the experimental data to confirm the validity of the theoretical model. These results present a new model of rectification for short channel lengths and its dependence on the extinction of AC signal through the channel.
Systematic review of diagnostic and prognostic host blood transcriptomic signatures of tuberculosis disease in people living with HIV
Authors: Mendelsohn Simon C , Verhage Savannah , Mulenga Humphrey , Scriba Thomas J , Hatherill Mark 
Published: May 2023

Background HIV-associated tuberculosis (TB) has high mortality; however, current triage and prognostic tools offer poor sensitivity and specificity, respectively. We conducted a systematic review of diagnostic and prognostic host-blood transcriptomic signatures of TB in people living with HIV (PLHIV). Methods We systematically searched online databases for studies published in English between 1990-2020. Eligible studies included PLHIV of any age in test or validation cohorts, and used microbiological or composite reference standards for TB diagnosis. Inclusion was not restricted by setting or participant age. Study selection, quality appraisal using the QUADAS-2 tool, and data extraction were conducted independently by two reviewers. Thereafter, narrative synthesis of included studies, and comparison of signatures performance, was performed. Results We screened 1,580 records and included 12 studies evaluating 31 host-blood transcriptomic signatures in 10 test or validation cohorts of PLHIV that differentiated individuals with TB from those with HIV alone, latent Mycobacterium tuberculosis infection, or other diseases (OD). Two (2/10; 20%) cohorts were prospective (29 TB cases; 51 OD) and 8 (80%) case-control (353 TB cases; 606 controls) design. All cohorts (10/10) were recruited in Sub-Saharan Africa and 9/10 (90%) had a high risk of bias. Ten signatures (10/31; 32%) met minimum WHO Target Product Profile (TPP) criteria for TB triage tests. Only one study (1/12; 8%) evaluated prognostic performance of a transcriptomic signature for progression to TB in PLHIV, which did not meet the minimum WHO prognostic TPP. Conclusions Generalisability of reported findings is limited by few studies enrolling PLHIV, limited geographical diversity, and predominantly case-control design, which also introduces spectrum bias. New prospective cohort studies are needed that include PLHIV and are conducted in diverse settings. Further research exploring the effect of HIV clinical, virological, and immunological factors on diagnostic performance is necessary for development and implementation of TB transcriptomic signatures in PLHIV.
Holistic care, implementation of physical activity and a healthy lifestyle in patients with PMS symptoms
Authors: Lepczyński Bartłomiej , Kułakowska Aleksandra , Siedlak Agnieszka , Kłakowicz Philip , Lechowski Sebastian 
Published: May 2023

Effective control of fertility and new social roles of women caused that the time when a woman experiences cyclical hormonal changes in the menstrual cycle and the possible adverse symptoms associated with it became the period prevailing during the reproductive period of a woman's life.
Premenstrual syndrome (PMS) comprises clinically significant physical and psychological symptoms that occur during the luteal phase of the menstrual cycle and cause significant distress and functional impairment.
A broadly understood change in lifestyle, diet, systematic increase in physical activity, reduction of stimulants, but above all, keeping a diary of observation of alarming symptoms positively affects the improvement of women's well-being, accelerates the diagnosis and start of treatment.
Human-Robot Cooperation: Coordinating Autonomous Mobile Robots and Human Order Pickers
Authors: Löffler Maximilian , Boysen Nils , Schneider Michael 
Published: May 2023

In the e-commerce era, efficient order fulfillment processes in distribution centers have become a key success factor. One novel technology to streamline these processes is robot-assisted order picking. In these systems, human order pickers are supported by autonomous mobile robots (AMRs), which carry bins for collecting picking orders, autonomously move through the warehouse, and wait in front of a shelf containing a requested stock keeping unit (SKU). Once a picker has approached a waiting AMR and placed the requested SKU into the respective bin, AMR and picker may separate and move toward other picking positions. In this way, pickers continuously move between different waiting AMRs without having to return to the depot. This paper treats the coordination of multiple AMRs and multiple pickers to minimize the makespan. We present a heuristic method for the deterministic case that can handle the requirements of large e-commerce fulfillment centers and successfully solves instances with more than one thousand picking positions. Based on the obtained solutions, the performance of our picking system is compared with the traditional warehouse setup without AMR support and to another work policy using fixed pairings of picker and AMR per order. We find that largely improved makespans can be expected. In addition, we analyze the effects of stochastic picking times, speed differences between AMRs and pickers, and a zoning strategy. The ripple effect caused by stochastic picking times, in which a single delay may cascade through a tightly synchronized schedule and deteriorate picking performance, can be effectively mitigated by separating the workforce into smaller subgroups. Another important finding is that pickers and AMR should have approximately the same travel speed because slower AMRs deteriorate system performance. Finally, zoning slightly decreases the flexibility of the system and should be used if dictated by organizational reasons. History: This paper has been accepted for the Transportation Science Special Issue on Emerging Topics in Transportation Science and Logistics. Supplemental Material: The online appendix is available at https://doi.org/10.1287/trsc.2023.1207 .