bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complementary Surface‐Enhanced Raman Scattering (SERS) and IR Absorption Spectroscopy (SEIRAS) with Nanorods‐on‐a‐Mirror
Authors: Oksenberg Eitan , Shlesinger Ilan , Tek Gökçen , Koenderink A. Femius , Garnett Erik C. 
Published: December 2022

AbstractThe surface‐enhanced counterparts of Raman scattering (SERS) and infrared (IR) absorption (SEIRAS) are commonly used to probe and identify nanoscale matter and small populations of molecules. The contrasting selection rules offer complementary vibrational information of bulk solids or solutions. In this study, a complementary surface‐enhanced vibrational spectroscopy approach is presented to probe the vibrational signature of metal‐bound molecular monolayers. Nanocavities are designed and produced with sharp and tunable visible (VIS) and mid‐IR gap resonances by placing nanorods on a mirror that is coated with a thin dielectric spacer. Their VIS resonances are tuned to match a 1.61 eV (770 nm) resonant excitation for SERS, while their mid‐IR resonances span the 1500–2800 cm−1 range (6.5–3.5 µm) in high resolution for SEIRAS, targeting CN bond vibrations at 2220 cm−1. Both the VIS and mid‐IR gap modes support spatially overlapping and highly enhanced near‐fields ensuring strong SERS and SEIRAS signals from the same monolayer molecular population. The differences in the vibrational information obtained with the two surface‐enhanced spectroscopies when probing coupled molecular vibrations are highlighted and the advantages of using such a platform for investigating cavity‐modified chemical reactions are discussed.
Double Paddle‐Wheel Enhanced Sodium Ion Conduction in an Antiperovskite Solid Electrolyte
Authors: Tsai Ping‐Chun , Mair Sunil , Smith Jeffrey , Halat David M. , Chien Po‐Hsiu , Kim Kwangnam , Zhang Duhan , Li Yiliang , Yin Liang , Liu Jue , Lapidus Saul H. , Reimer Jeffrey A. , Balsara Nitash P. , Siegel Donald J. , Chiang Yet‐Ming 
Published: December 2022

AbstractAntiperovskite structure compounds (X3AB, where X is an alkali cation and A and B are anions) have the potential for highly correlated motion between the cation and a cluster anion on the A or B site. This so‐called “paddle‐wheel” mechanism may be the basis for enhanced cation mobility in solid electrolytes. Through combined experiments and modeling, the first instance of a double paddle‐wheel mechanism, leading to fast sodium ion conduction in the antiperovskite Na3−xO1−x(NH2)x(BH4), is shown. As the concentration of amide (NH2−) cluster anions is increased, large positive deviations in ionic conductivity above that predicted from a vacancy diffusion model are observed. Using electrochemical impedance spectroscopy, powder X‐ray diffraction, synchrotron X‐ray diffraction, neutron diffraction, ab initio molecular dynamics simulations, and NMR, the cluster anion rotational dynamics are characterized and it is found that cation mobility is influenced by the rotation of both NH2− and BH4− species, resulting in sodium ion conductivity a factor of 102 higher at x = 1 than expected for the vacancy mechanism alone. Generalization of this phenomenon to other compounds could accelerate fast ion conductor exploration and design.
Binary Microcrystal Additives Enabled Antisolvent‐Free Perovskite Solar Cells with High Efficiency and Stability
Authors: Wang Deng , Chen Jiabang , Zhu Peide , Qiao Ying , Hu Hang , Zeng Jie , Zhang Jiyao , Qu Geping , Wang Yanggang , Wang Xingzhu , Jen Alex K.‐Y. , Xu Baomin 
Published: December 2022

AbstractDeveloping a facile method to prepare high‐quality perovskite films without using the antisolvent technique is critical for upscaling production of perovskite solar cells (PVSCs). However, the as‐prepared formamidinium (FA)‐based perovskite films often exhibit poor film quality with high density of defects if antisolvent is not used, limiting the photovoltaic performance and long‐term stability of derived PVSCs. Herein, this work adopts pre‐synthesized 3D methylammonium lead chloride (MAPbCl3) and 1D 2‐aminobenzothiazole lead iodide (ABTPbI3) microcrystals into self‐drying perovskite precursors, which serve as seed crystals to promote nucleation and growth of FAPbI3‐based perovskites without requiring antisolvent extraction. The combined binary microcrystals facilitate the formation of a dense and pinhole‐free perovskite film with a stable perovskite lattice and defect‐healed grain boundaries, enabling efficient charge carrier transfer and reduced non‐radiative recombination loss. As a result, the best‐performing inverted architecture device exhibits a champion power conversion efficiency of 23.27% for small‐area devices (0.09 cm2) and 21.52% for large‐area devices (1.0 cm2). These values are among the highest efficiencies reported for antisolvent‐free PVSCs. Additionally, the unencapsulated device shows enhanced moisture, thermal, and operational stabilities, and maintains 92% of its initial efficiency after being held at the maximum power point for 1000 h.
Pd‐Catalyzed Coupling Cyclization of δ, ϵ‐Alkenyl Oxime toward Access to 1,2‐Oxezapines
Authors: Zhao Chuang , Dong Ah‐Ying , Ju Dongyan , Huang Jianhong , Jia Ran , Liu Yu , Zhao Jinbo 
Published: December 2022

AbstractThe Pd‐catalyzed coupling cyclization of δ,ϵ‐alkenyl oxime with (hetero)aryl and halides is presented, which affords seven membered N,O‐heterocycle, tetrahydro‐1,2‐oxezapines, in moderate to good yields. DFT calculation favors an outer‐sphere anti‐oxypalladation pathway and provides key insights on the reaction mechanism. The reaction represents an unprecedented example of seven‐membered ring formation by heterocyclization.
Management paradigms for chronic rhinosinusitis in individuals with asthma: An evidence‐based review with recommendations
Authors: Gill Amarbir S. , Alt Jeremiah A. , Detwiller Kara Y. , Rowan Nicholas R. , Gray Stacey T. , Hellings Peter W. , Joshi Shyam R. , Lee Jivianne T. , Soler Zach M. , Tan Bruce K. , Taylor‐Cousar Jennifer L. , Wise Sarah K. , Wu Tara J. , Beswick Daniel M. 
Published: December 2022

AbstractBackgroundDespite the significant morbidity associated with chronic rhinosinusitis (CRS) in individuals with asthma (CRSwA), there is a paucity of codified, evidence‐based management strategies for CRS in this population.MethodsUsing PubMed, Embase, and Cochrane Review Databases, a systematic review was performed covering management strategies for CRSwA. A total of 5903 articles were screened, and 70 were included for full‐text analysis. After application of exclusion criteria, 53 articles comprised the qualitative synthesis. The level of evidence was graded and benefit‐harm assessments, as well as value judgment and recommendations, were providedResultsStrong evidence confirms the benefit of oral and topical medications on sinonasal‐specific outcomes in individuals with CRSwA; there is low‐grade evidence demonstrating that these agents improve lung function and/or asthma control. Moderate to strong evidence suggests that endoscopic sinus surgery (ESS) improves both sinonasal‐ and asthma‐specific quality of life. Although there is insufficient to low evidence to indicate that ESS improves pulmonary function in this population, data indicate a positive impact of this intervention on asthma control. Biologic medications strongly improve both subjective and objective sinonasal‐ and asthma‐specific outcomes.ConclusionEvidence supports managing CRS in individuals with CRSwA in a stepwise fashion, starting with traditional nonbiologic oral and topical medication, and escalating to second‐line treatments, such as ESS and biologics. Optimal treatment of individuals who have CRSwA often requires concurrent, directed management of asthma, as not all CRS interventions impact asthma status.
A review of nonfullerene solar cells: Insight into the correlation among molecular structure, morphology, and device performance
Authors: Xin Jingming , Li Wangchang , Zhang Yutong , Liang Qiuju , Song Chunpeng , Zhao Yuzhen , He Zemin , Liu Jiangang , Ma Wei 
Published: December 2022

AbstractNonfullerene acceptors (NFAs) lead the continuous development of organic solar cells (OSCs) with competitive efficiency over 19%. Design and synthesis of novel photovoltaic materials are effective methods to improve the OSCs performance, which can regulate the optoelectric properties, such as energy level, absorption spectra, charge transport, and so on. So far, hundreds of NFAs have been reported. Meanwhile, it has been demonstrated that intrinsic morphology of active layer is partially determined by the chemical structures of NFAs. Hence, only in‐depth understanding of the relationship between different structures of NFAs and morphology can guide the molecular design of NFAs for highly efficient OSCs. Herein, we review some state‐of‐the‐art NFAs according to their functional moieties, that is, arene core, end group and side chain, and discuss the relationship between molecular structure, morphology and device parameter. Additionally, the challenges and prospects for further development of OSCs based on NFAs are briefly considered. This review brings a unique insight into structure–function correlation in this field, which may help to rapidly develop efficient OSCs.
Enhancing surface‐to‐bulk stability of layered Co‐free Ni‐rich cathodes for long‐life Li‐ion batteries
Authors: Yang Zhaofeng , Wang Zhihong , Zhu Yihua , Jiang Hao , Li Chunzhong 
Published: December 2022

AbstractLayered Co‐free Ni‐rich cathodes are the most cost‐effective for high‐energy‐density Li‐ion batteries (LIBs), yet the structural instability and interfacial side reactions seriously hamper their commercial applications versus the Co‐contained counterpart. Herein, a synchronous Ge‐doping and Li4GeO4‐coating of the Co‐free Ni‐rich cathodes have been realized to tackle these limitations during high‐temperature lithiation of the corresponding hydroxide precursors. The nonmagnetic Ge4+ doping effectively relieves the magnetic frustration and the lattice oxygen loss with reduced cation mixing and gas emission. The Li‐ion conductive and anti‐erosive Li4GeO4 coatings contribute to enhance the surface chemistry stability and Li‐ion migration interface kinetics. Consequently, the resulting Co‐free Ni‐rich cathodes delivers a high reversable capacity of 223.3 mAh g−1 at 0.1 C and maintains 127.5 mAh g−1 even at 10C within 2.7–4.4 V. More impressively, it displays high‐capacity retention of 90.5% in coin‐type half‐cell after 150 cycles and 80.5% in pouch‐type full‐cell after 500 cycles at 3C, demonstrating a long‐term cycle life.
Switching the Mode of Cell Death between Apoptosis and Autophagy by Histone Deacetylase 6 Inhibition Levels
Authors: Zhou An‐Min , Wang Meng‐Meng , Su Yan , Yu Zheng‐Hong , Liu Hong‐Ke , Su Zhi 
Published: December 2022

AbstractInhibition of histone deacetylase (HDAC) has been demonstrated to be an effective strategy for cancer treatment. In this work, we have developed a new agentIr‐VPA, which exhibits the cell death mode switching between apoptosis and autophagy due to the distinct level of HDAC6 inhibition.Ir‐VPAindicates the best anticancer activity to HeLa cells, and could be hydrolyzed due to the high expression of the esterase in HeLa cells.Ir‐VPAcould accumulate in nuclei, induce severe DNA damages and cell cycle arrest at G2/M phase. The anticancer mechanism ofIr‐VPAto HeLa cells was dependent on the HDAC6 inhibitory performance, as the caspase dependent apoptosis at low concentration (IC50) and autophagy with the autophagy flux blockage at high concentration (2×IC50). This is resulted from the distinct inhibitory levels of HDAC6, as moderate/complete inhibition at the concentration of IC50/2×IC50.In the presence of autophagic inhibitor chloroquine, the apoptotic population elevated from 32.7 % to 61.7 %, indicating thatIr‐VPAcould activate apoptotic process through the autophagolysosome fusion inhibition.Ir‐VPAalso exhibits excellent antiproliferative behavior to 3D HeLa multicellular tumor spheroids (MCTSs). This work not only provided a new HDAC6 inhibitor and novel anticancer mechanism for the effective treatment of cervical cancer, but also demonstrated the strategy to conjugate the metal fragment with active organic drug to enhance the anticancer performance.
Influence of oxytocin on parenting behaviors and parent–child bonding: A systematic review
Authors: Shorey Shefaly , Asurlekar Alpana Rajesh , Chua Jing Shi , Lim Lina Hsiu Kim 
Published: December 2022

AbstractOxytocin (OT) plays a pivotal role in early parent–child relationship formation and bonding that is critical for the social, cognitive, and emotional development of the child. Therefore, this systematic review aims to consolidate all available evidence regarding the associations of parental OT concentration levels with parenting behavior and bonding within the past 20 years. A systematic search was conducted in five databases from 2002 to May 2022, and 33 studies were finalized and included. Due to the heterogeneity of the data, findings were presented narratively based on the type of OT and parenting outcomes. Current evidence strongly suggests that parental OT levels are positively related to parental touch and parental gaze and affect synchrony and observer‐coded parent–infant bonding. No gender difference in OT levels was observed between fathers and mothers, but OT strengthens affectionate parenting in mothers and stimulatory parenting in fathers. Child OT levels were also positively associated with parental OT levels. Family and healthcare providers could encourage more positive touch and interactive play between parent and child to strengthen parent–child relationships.
Range expansion and first observation of Tridacna noae (Cardiidae: Tridacninae) in American Sāmoa
Authors: Marra‐Biggs Paolo , Fatherree James , Green Alison , Toonen Robert J. 
Published: December 2022

AbstractGiant clams are ecologically important, benefitting species of all trophic levels. But numerous populations have declined drastically in numbers due to past intensive exploitation that led to their listing in both CITES Appendix II and IUCN Red List of Threatened Species. However, giant clams are notoriously difficult to identify, and recent molecular work has revealed that morphological misidentification of giant clams have confounded current population assessments and extinction risk. The most recent study of the status of giant clams in the Samoan Archipelago was published in a journal over 20 years ago, without molecular corroboration of visual identifications. Using morphologic characteristics and ezRAD genetic techniques, we identify the existence of Tridacna noae in the Samoan Archipelago, presenting the first observation and a resulting range expansion. Accurately identifying the extant species in the archipelago is the first step toward a much‐needed population status assessment to effectively manage these long‐lived species.
Genetic population dynamics of the critically endangered scalloped hammerhead shark (Sphyrna lewini) in the Eastern Tropical Pacific
Authors: Harned Sydney P. , Bernard Andrea M. , Salinas‐de‐León Pelayo , Mehlrose Marissa R. , Suarez Jenifer , Robles Yolani , Bessudo Sandra , Ladino Felipe , López Garo Andrés , Zanella Ilena , Feldheim Kevin A. , Shivji Mahmood S. 
Published: December 2022

AbstractThe scalloped hammerhead shark,Sphyrna lewini, is a Critically Endangered, migratory species known for its tendency to form iconic and visually spectacular large aggregations. Herein, we investigated the population genetic dynamics of the scalloped hammerhead across much of its distribution in the Eastern Tropical Pacific (ETP), ranging from Costa Rica to Ecuador, focusing on young‐of‐year animals from putative coastal nursery areas and adult females from seasonal aggregations that form in the northern Galápagos Islands. Nuclear microsatellites and partial mitochondrial control region sequences showed little evidence of population structure suggesting that scalloped hammerheads in this ETP region comprise a single genetic stock. Galápagos aggregations of adults were not comprised of related individuals, suggesting that kinship does not play a role in the formation of the repeated, annual gatherings at these remote offshore locations. Despite high levels of fisheries exploitation of this species in the ETP, the adult scalloped hammerheads here showed greater genetic diversity compared with adult conspecifics from other parts of the species' global distribution. A phylogeographic analysis of available, globally sourced, mitochondrial control region sequence data (n = 1818 sequences) revealed that scalloped hammerheads comprise three distinct matrilines corresponding to the three major world ocean basins, highlighting the need for conservation of these evolutionarily unique lineages. This study provides the first view of the genetic properties of a scalloped hammerhead aggregation, and the largest sample size‐based investigation of population structure and phylogeography of this species in the ETP to date.
Systematic review reveals sexually antagonistic knockouts in model organisms
Authors: Harper Jon Alexander , Morrow Edward H. 
Published: December 2022

AbstractSexual antagonism is thought to be an important selective force in multiple evolutionary processes, but very few examples of the genes involved are known. Such a deficit of loci could partially be explained by the lack of overlap in terminology between scientific disciplines. Following a similar review in humans, we searched systematically for studies that described genes with sexually antagonistic or sex‐opposite effects in any taxa, using terms designed to capture alternative descriptions of sexual antagonism. Despite drawing on a potentially very large pool of studies we found only eight articles, which between them described seven candidate variants, five of these were gene knockouts. In every case, the variants had net negative effects on the focal trait. One locus was independently validated between studies, but in comparison to previous data on variants in humans and the fruit‐fly, the studies generally suffered from small sample sizes, with concomitant high variance. Our review highlights the radically different effects that gene deletions can have on males and females, where the beneficial effects seen in one sex may facilitate the evolution of gene loss. We searched systematically for genetic variants with sexually antagonistic or sex‐opposite effects in any taxa. Of 2116 articles, we found seven candidate variants, five of which were gene knockouts. Our review highlights the radically different effects that gene deletions can have on males and females, where the beneficial effects seen in one sex may facilitate the evolution of gene loss.
Fine‐scale diversity of prey detected in humpback whale feces
Authors: Reidy Rhonda D. , Lemay Matthew A. , Innes Katie G. , Clemente‐Carvalho Rute B. G. , Janusson Carly , Dower John F. , Cowen Laura L. E. , Juanes Francis 
Published: December 2022

AbstractPredator diets are largely influenced by prey availability and abundance. Yet, in heterogenous marine environments, identifying the prey species consumed by diving mammals remains a fundamental challenge. For rorqual whales, the energetic constraints of prey engulfment require that the whales seek areas of high prey abundance and execute discrete lunge feeding events on patches of high‐density prey. Prey occurrences in feces should therefore provide meaningful insight into the dominant taxa in food patches selected by the animal. We investigated the prey consumed by humpback whales in three regions in southern British Columbia (BC), Canada, using opportunistic fecal sampling, microscopy, and DNA metabarcoding of 14 fecal samples. Fish including Pacific herring (Clupea pallasii), hake (Merluccius productus), and eulachon (Thaleichthys pacificus) were the most common fish species potentially targeted by humpback whales in two regions. The krill Euphausia pacifica was the most prevalent invertebrate DNA detected in all three regions, while sergestid and mysid shrimp may also be important. High DNA read abundances from walleye pollock (Gadus chalcogrammus) and sablefish (Anoplopoma fimbria) were also recovered in one sample each, suggesting that juveniles of these semi‐pelagic species may occasionally be targeted. In general, we observed heavily digested fecal material that drove substantial dissimilarities in taxonomic resolution between polymerase chain reaction‐based and morphological analyses of the feces. Pacific herring and walleye pollock were the only prey species confirmed by both methods. Our results highlight that molecular and visual analyses of fecal samples provide a complementary approach to diet analysis, with each method providing unique insight into prey diversity.
Relationship between salmon egg subsidy and the distribution of an avian predator
Authors: Yamada Taihei , Katahira Hirotaka , Miura Kazuki , Nakamura Futoshi 
Published: December 2022

AbstractAs a spatial subsidy, which is the phenomenon of transferring resources from a donor system to a recipient system, anadromous salmonids contribute to the supply of marine‐derived nutrients to freshwater and terrestrial systems. Live salmon and salmon carcasses and eggs are utilized by various organisms and affect their abundance and distribution. However, the evaluation of the effect of salmon subsidies on the abundance and distribution of terrestrial animals is biased toward predators or scavengers that utilize spawning adults and carcasses, and few studies have focused on the effect of salmon eggs as a subsidy. To avoid underestimating the function of salmon subsidies, the response to the availability of salmon eggs in various systems should be investigated. Here, we investigated the abundance and feeding behavior of the brown dipperCinclus pallasii, as a consumer of salmon eggs, based on the hypothesis that the availability of salmon eggs affects the diet composition and stream distribution of this small predator. In addition, to test whether changes in the abundance of brown dippers are determined by salmon spawning, their abundance was compared upstream and downstream of the check dams in three streams during the peak spawning period. Brown dippers used salmon eggs during the spawning season (53.7% of diet composition), and their abundance increased as the number of spawning redds increased. In contrast, this pattern was not observed upstream of the check dam. These results suggested that the abundance and stream distribution of brown dippers vary according to the variation in the spatiotemporal availability of salmon eggs.