bluuebunny/crossref_metadata_2025_split huggingface dataset:
People’s Perceptions and Coping Strategies During the COVID-19 Pandemic: A Phenomenological-Longitudinal Study in Bangladesh
Authors: Jannat Taslima , Omar Nor Asiah , Che Senik Zizah , Ayob Abu Hanifah , Al Mamun Abdullah , Arefin Md. Shamshul , Hijrah Hati Sri Rahayu 
Published: April 2023

By emphasizing the Terror Management Theory, this study investigated the participants’ perceptions, psychological experiences, coping strategies, and behavioral changes during the pandemic in Bangladesh in two phases: first, after the pandemic’s immediate outbreak, and second, after 3 months of the pandemic (daily infection cases were very high). To perform the research, an empirical-phenomenological method was used. Findings indicate that at the first stage, participants’ death phobia was extremely high, and poor medical facilities, religious struggles, imprudent behavior of others, concerns for family members, and a tendency to compare the socioeconomic status with other developed countries affected participants’ emotions severely. Later on, participants’ perceptions of the disease changed significantly. This study highlights that people’s behavior varies depending on whether the thought of death is in the center or on the periphery of their attention. In both stages, religious faith and rituals played a crucial role in coping with the crisis situation.
Are We Losing Connection? Lived Experience of Online Mutual Aid Groups During the COVID-19 Pandemic
Authors: Lee Daren , Antonino Raffaello 
Published: April 2023

Background: The current UK based study aimed to explore the experiences of individuals attending online mutual aid groups for alcohol use, while their face-to-face groups were suspended during the COVID-19 pandemic. Emerging evidence suggests that the pandemic and concomitant isolation is associated with elevated mental health problems. Furthermore, historical community-wide crises are associated with increases in alcohol consumption. Due to the paucity of qualitative research on the subjective experience of online mutual aid groups, an interpretative phenomenological analysis was undertaken to explore group members’ experiences. Methods: A sample of six eligible members of online alcohol mutual aid groups were recruited and completed semi-structured interviews during the COVID-19 pandemic between October 2020 and February 2021. Interpretative phenomenological analysis was used to identify key themes and evidenced with salient quotations. Results: The superordinate theme developing an understanding of the differences between face-to-face and online group proceedings was identified, which is presented and unpacked with evidential quotes. Conclusion: The study explicates group members’ perceived differences between online and face-to-face experiences. Some participants valued the increased control and anonymity of online groups, while others missed the profound intimate connection that face-to-face groups fostered. It is recommended that future provision is informed by service-user voice to develop an attunement with the subjectivity of mutual aid group members’ experiences.
Intraoperative computed tomography during fenestrated and branched endovascular aortic repair: a feasibility study
Authors: Schrøder-Aasen Anne Marte , Carling Ulrik , Aaløkken Trond Mogens , Rasmussen Margrethe Kallestad , Dorenberg Eric 
Published: April 2023

Background Endovascular aortic repair with fenestrated or branched endografts is technically challenging, and proper intraoperative assessment of all stent graft components with only angiography and fluoroscopy can be difficult. Intraoperative computed tomography (CT) imaging can be a valuable aid for the operators in the evaluation of stent grafting results prior to completion of surgery. Purpose To examine the feasibility of performing intraoperative CT imaging during fenestrated and branched endovascular aortic repair (f-bEVAR) under sterile conditions and with patients under general anesthesia. Material and Methods Intraoperative CT imaging was performed in 10 patients undergoing elective aortic repair with fenestrated or branched endografts. Adverse events, time consumption for CT set-up and image acquisition, and additional radiation dose to the patient were recorded. CT image quality was graded. Immediate corrective maneuvers performed based on the CT findings was registered. Results There were no adverse events related to intraoperative CT imaging. The median additional operating time by including intraoperative CT was 16 min (interquartile range [IQR] = 12–19), comprising 7% of the median total operating time. The median estimated additional radiation dose to the patient was 4.8 mSv (IQR = 3.8–4.9). All intraoperative CT examinations were considered to be of sufficient quality for stent graft evaluation. No immediate corrective procedures were performed on the basis of CT findings in this study cohort. Conclusion CT imaging intraoperatively during f-bEVAR is feasible with an acceptable increase in operating time and radiation dose.
Oral vinorelbine in young patients with desmoid-type fibromatosis
Authors: Kornreich Laure , Orbach Daniel , Nicolas Nayla , Brisse Hervé J , Berlanga Pablo , Defachelles Anne-Sophie , Mansuy Ludovic , Verite Cécile , Saumet Laure , Karanian Marie , Corradini Nadège 
Published: April 2023

Background: Desmoid-type fibromatosis are rare intermediate tumors in children and adolescents. Owing to local aggressiveness and relapse, systemic treatment for symptomatic advanced or progressive forms is recommended. Following promising results in adult patients, oral vinorelbine is investigated in young patients. Methods: A retrospective review of young patients (<25 years old) with advanced or progressive desmoid type fibromatosis treated with oral vinorelbine in eight large centers of the Société Française des Cancers de l’Enfant was performed. In addition to tumor assessment according to RECIST 1.1, pre-treatment and during-treatment imagery were reviewed centrally to assess tumor volume and estimate fibrosis score through the change in percentage in hypoT2 signal intensity. Results: From 2005 to 2020, 24 patients (median age 13.9 years [range, 1.0-23.0]) received oral vinorelbine. Median number of prior systemic lines of treatment was 1 (range, 0-2), mainly based on intravenous low dose methotrexate and vinblastine. Before vinorelbine initiation, all patients had a progressive disease: radiological for 19, radiological and clinical (pain) for three and only clinical for two. Oral vinorelbine was delivered for a median duration of 12 months (range, 1-42). The toxicity profile was favorable, with no grade 3-4 event. Overall response estimated on 23 evaluable patients according to RECIST 1.1 criteria was three partial responses (13%), 18 stabilization (78%) and two progressive disease (9%). Overall progression-free survival was 89.3% (95% confidential intervals 75.2-100) at 24 months. Four stable tumors according to standard RECIST criteria displayed a partial response with > 65% tumor volume reduction. Among 21 informative patients, the estimated fibrosis score decreased for 15 patients, was stable for four patients and increased for two patients. Conclusion: Oral vinorelbine seems to be effective to control advanced or progressive desmoid type fibromatosis in young patients, with a well-tolerated profile. These results support testing this drug as first-line alone or in combination to improve response rate while preserving quality of life.
Lignocellulosic Materials in Building Elements. Part II. Cement Light-Weight Building Bricks
Authors: Basta Altaf H. , Fadl Nairn A. , Gabra Usama I. 
Published: April 2023

Wood processing and agricultural wastes (spruce wood, bagasse and cotton stalk) were used for the production of cemented lignocellulosic bricks. Pretreatment with 50% linseed oil, followed by hardening at 120°C was carried out to improve water repellency. Several variables were investigated during the formation of the bricks, such as the mesh size of the lignocellulosic waste, the cement to wood ratio and the use of some additives, e.g. urea formaldehyde, aluminium oxide powder, emulsion acrylic (Nitobond AR), hemihydrate gypsum and polyvinyl alcohol. The results obtained indicate that bricks prepared by adding Nitobond AR to cement-wood mixtures have higher strength than those obtained using other additives. Also, bricks produced by blending treated wood waste with cement have better properties than those produced from blends of treated agricultural wastes (bagasse and barked cotton stalk) with cement. The field of application of the product was considered. A plant for the production of cemented lignocellulosic bricks was also designed.
Synthesis of Polyarylates with Allylic Side Groups. Part 3. Polyarylates Based on 1,3-bis(3-allyl-4-hydroxybenzylidene) Acetone
Authors: Zadrozna I. , Brzozowski Z.K. , Noniewicz K. , Dyrda M. 
Published: April 2023

Several UV-sensitive polyarylates based on 1,3-bis(3-allyl-4-hydroxybenzylidene)acetone were obtained by interfacial poly-condensation foruse as potential photo-sensitive polymers. The structures of the UV-sensitive monomers and polymers obtained were confirmed using 1R, 1HNMR and UV spectroscopies. Their physical, chemical and mechanical properties were determined. The investigations show that some of the new polymers possessing allylic groups as photosensitive side chains conjugated with bisbenzylideneketone groups exhibit different behaviour under UV light exposure from polyarylates based only on bisbenzylideneketone bisphenols presented in our previous work.
An Experimental Study of Paint-Stripping Using an Excimer Laser
Authors: Galantucci L.M. , Gravina A. , Chita G. , Cinquepalmi M. 
Published: April 2023

An excimer laser paint stripping process on metallic surfaces has been investigated, applicable to all those situations, such as adhesive bonding or spot welding, where a localised removal of the surface coating on single parts before assembly could be less expensive and better in quality than the ones realised with traditional methods. This process, due to the properties of the UV laser radiation used, is also suitable for paint stripping on already thermal treated metallic surfaces and plastic composites surfaces. The absence of contact of the laser “tool” with the coating and the easy removal of products formed during the process is another important advantage of this method. Treating radioactive or contaminated parts is also possible, keeping the process in a closed chamber. Several kinds of polymer coatings have been tested for paint stripping experiments applied on aluminium and low carbon steel substrates, with different composition, colours, and thicknesses. The results obtained show that high quality surfaces can be obtained using this treatment, but the processing time is long. These characteristics make the method suitable for treatment of small zones when either high surface quality, or absence of contact, is essential.
Synthesis of Polyarylates with Allylic Side Groups. Part 4. Polyarylates Based on Chalcones
Authors: Zadrozna I. , Wyszomierska A. 
Published: April 2023

Several UV sensitive polyarylates based on chalcones with allylic groups side chains for potential use as photosensitive polymers were obtained by interfacial polycondensation. The structure of the UV-sensitive monomers and polymers obtained has been confirmed using IR, 1H NMR and UV spectroscopies. Their physical, chemical and mechanical properties have also been determined. The investigations show that some of the new polymers bearing allylic groups as photosensitive side chains conjugated with benzylideno-acetophenone groups exhibit different behaviour under UV light exposure from the polyarylates based only on bisbenzylideneketone bisphenols, presented in our previous work.
Pharmacokinetic approach in therapeutic monitoring of antineoplastic drugs and the impact on pharmacoeconomics: A systematic review
Authors: Barbosa Islania Almeida Brandão , Silva Taiane Candeias da , Souza Monielly Vasconcelos Pereira de , Pedreira Lorena Argolo , Godoy Ana Leonor Pardo Campos 
Published: April 2023

Objectives Therapeutic drug monitoring aims to quantify the concentration of a drug in a biological matrix. In oncology, the therapeutic arsenal is vast and therapeutic drug monitoring optimizes treatment and reduces costs. This review will analyze the financial impact of therapeutic monitoring of anticancer drugs in healthcare institutions. Methods Keywords were selected using Decs (MeSH). Through the Pubmed, Scopus, and Virtual Health Library (VHL) databases, 74 articles were found, of which 4 meet the inclusion criteria. Methodological quality and risk of bias were assessed according to the Research Triangle Institute Item Bank (RTI-Item Bank) scale. Key findings Therapeutic drug monitoring is an important tool for dose reduction or dose increase due to toxicity and lack of response, respectively. The main barriers are associated costs and lack of cost–benefit data. An alternative is to use population pharmacokinetic models, measured plasma concentration(s) and relevant patient characteristics, estimated individual pharmacokinetic parameters, and predicted drug concentrations at any point in the dosing range. Conclusions Therapeutic drug monitoring is understood as a technology that adds costs to payers. Future studies should generate clinical evidence of population pharmacokinetics from therapeutic drug monitoring studies.
Steroids Provide Temporary Improvement of Refractory Pain Following Subarachnoid Hemorrhage
Authors: Jaffa Matthew N. , Podell Jamie E. , Foroutan Arshom , Motta Melissa , Chang Wan-Tsu W. , Cherian Jacob , Pergakis Melissa B. , Parikh Gunjan Y. , Simard J. Marc , Armahizer Michael J. , Badjatia Neeraj , Morris Nicholas A. 
Published: April 2023

Introduction Evidence for optimal analgesia following subarachnoid hemorrhage (SAH) is limited. Steroid therapy for pain refractory to standard regimens is common despite lack of evidence for its efficacy. We sought to determine if steroids reduced pain or utilization of other analgesics when given for refractory headache following SAH. Methods We performed a retrospective within-subjects cohort study of SAH patients who received steroids for refractory headache. We compared daily pain scores, total daily opioid, and acetaminophen doses before, during, and after steroids. Repeated measures were analyzed with a multivariable general linear model and generalized estimating equations. Results Included 52 patients treated with dexamethasone following SAH, of whom 11 received a second course, increasing total to 63 treatment epochs. Mean pain score on the first day of therapy was 7.92 (standard error of the mean [SEM] .37) and decreased to 6.68 (SEM .36) on the second day before quickly returning to baseline levels, 7.36 (SEM .33), following completion of treatment. Total daily analgesics mirrored this trend. Mean total opioid and acetaminophen doses on days one and two and two days after treatment were 47.83mg (SEM 6.22) and 1848mg (SEM 170.66), 34.24mg (SEM 5.12) and 1809mg (SEM 150.28), and 46.38mg (SEM 11.64) and 1833mg (SEM 174.23), respectively. Response to therapy was associated with older age, decreasing acetaminophen dosing, and longer duration of steroids. Hyperglycemia and sleep disturbance/delirium effected 28.6% and 55.6% of cases, respectively. Conclusion Steroid therapy for refractory pain in SAH patients may have modest, transient effects in select patients.
Incidences of and risk factors for clinical and subclinical contrast-associated acute kidney injury in patients who underwent neuroendovascular surgery
Authors: Mitaka Chieko , Teranishi Kohsuke , Wakita Mitsuru , Misawa Shigeki , Nojiri Shuko , Satoh Daizoh , Hayashida Masakazu 
Published: April 2023

Background Contrast-associated acute kidney injury (CA-AKI) can develop after intravascular administration of iodinated contrast media. Neutrophil gelatinase-associated lipocalin (NGAL) is an early marker for AKI that helps to detect subclinical CA-AKI. We investigated the incidence of and risk factors for clinical and subclinical CA-AKI in patients who underwent neuroendovascular surgery. Methods We retrospectively investigated 228 patients who underwent neuroendovascular surgery in 2020. Changes in serum creatinine and urine output were used to detect clinical CA-AKI. Urine NGAL concentration was used to detect subclinical CA-AKI in 67 out of 228 patients. Results In 228 patients, serum creatinine, hemoglobin, hematocrit, total protein, and blood urea nitrogen (BUN) decreased significantly ( p < 0.001) after surgery. However, serum creatinine decreased less significantly ( p < 0.05) than hemoglobin, hematocrit, total protein, and BUN on postoperative Day 3. Two patients out of 228 developed clinical CA-AKI, and seven patients out of 67 with urine NGAL measurements developed subclinical CA-AKI. Multivariate regression analysis revealed that diabetes mellitus and carotid artery stenosis were significantly ( p < 0.05) associated with the development of clinical and/or subclinical CA-AKI. Conclusion There was a large difference between the incidences of clinical CA-AKI (0.88%) and subclinical CA-AKI (10.4%). The difference might have primarily resulted from the different sensitivities between serum creatinine and urine NGAL and possibly from underestimation of the incidence of clinical AKI due to a postoperative decrease in serum creatinine caused by hemodilution. In addition to diabetes mellitus, carotid artery stenosis could also be a risk factor for CA-AKI.
Evaluation of Efficiency of Distal Shoe Space Maintainer: A Systematic Review
Authors: Dadpe Mahesh V. , Chordiya Nikita A. , Kale Yogesh J. , Dahake Prasanna T. , Kendre Shrikant B. , Mankar Shrawani S. 
Published: April 2023

Aim: A space deficiency in the dental arch may result from the early loss of a second deciduous molar before the eruption of the first permanent molar. In this circumstance, the Distal Shoe Space Maintainer (DSSM) is recommended to prevent space loss. We aimed to evaluate the effectiveness and safety of this device. Materials and Methods: PUBMED, Cochrane libraries, Google scholar, Ebsco, and Science Gov. were all thoroughly searched. The effectiveness of DSSM as measured by patient tolerance and gingival response to DSSM was our main outcome goal. Also, we evaluated each study’s quality and design. Results: Eleven publications that fit the criteria for inclusion were examined after duplicates were removed. These papers were eventually chosen and thoroughly examined. The studies provided insufficient details regarding the efficacy of space maintenance or gingival response to the DSSM. Conclusion: The main concern is to provide maximum benefit to the patient with minimum discomfort, maximum effectiveness, more cooperation and less chair-side time which can be achieved by the modified distal shoe appliance when compared with the conventional, as it was more stable and required less chair-side time. Though the appliances were designed keeping all the basic requirements in mind, it is firmly recommended to assess more patient-centered outcomes of DSSMs.
Does Prehabilitation Before Surgery Affect Return to Sport in Baseball Pitchers With Partial Ulnar Collateral Ligament Tears?
Authors: Snigar Kourtney , Paul Ryan W. , Spada Joshua M. , Zareef Usman , Hall Anya , Erickson Brandon J. , Ciccotti Michael G. , Thomas Stephen J. 
Published: April 2023

Background: Purposeful rehabilitation before surgery (prehabilitation) has been researched and implemented in the treatment of anterior cruciate ligament tears. However, it is unclear whether prehabilitation would affect outcomes for baseball pitchers with partial ulnar collateral ligament (UCL) tears. Purpose/Hypothesis: The purpose of this study was to determine whether baseball pitchers with partial UCL tears who completed ≥4 weeks of prehabilitation (prehab group) have different return to play (RTP) outcomes than pitchers with 0 to 3 weeks of preoperative physical therapy (no prehab group). We hypothesized that pitchers in the prehab group would have similar RTP rates compared with pitchers in the no prehab group. Study Design: Cohort study; Level of evidence, 3. Methods: Baseball pitchers of all competitive levels who underwent primary UCL reconstruction (UCLR) or UCL repair between 2010 and 2019 were included. Physician chart notes, magnetic resonance images, and operative notes were screened to confirm primary UCLR or UCL repair of a partial UCL tear and to identify whether the nonoperative treatment had been attempted. Patients were contacted via RedCap for postoperative complications, reoperations, RTP, and patient-reported outcomes (Kerlan-Jobe Orthopaedic Clinic score, Andrews-Timmerman score, Conway-Jobe score, and satisfaction). Results: Overall, 105 baseball pitchers (n = 55 prehab group; n = 50 no prehab group) were included and evaluated at 3.4 ± 2.5 years postoperatively. Six pitchers underwent UCL repair, and 99 pitchers underwent UCLR. All demographic characteristics were similar between groups except the prehab group received a gracilis graft more frequently (76.5% vs 51.2%; P = .038). The RTP rate (prehab [88.1%] vs no prehab [93.8%]; P = .465) was similar between groups. All other postoperative outcomes were also similar between groups, including revision rates and patient-reported outcomes. Conclusion: Postoperative and patient-reported outcomes did not differ significantly between pitchers with partial UCL tears who performed rehabilitation before UCL surgery and pitchers who did not attempt a significant period of rehabilitation before UCL surgery. Clinicians should feel comfortable recommending rehabilitation for patients with partial UCL tears who wish to attempt a period of nonoperative treatment, as postoperative outcomes are not affected if UCL surgery is later needed.