bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prototipo derivado de los prebióticos del yacón para problemas digestivos y diabetes
Authors: Oñate Perpiñan Yuneidys Mariet 
Published: August 2023

La tendencia actual es una alimentación saludable que contenga elementos naturales beneficiosos para la salud; por tanto el proyecto de investigación tuvo como objetivo diseñar un prototipo en polvo, que contenga un edulcorante rico en fibra mediante la extracción de los prebióticos presentes en un tubérculo conocido como “Yacón”, su nombre científico es Smallanthus sonchifolius, con la finalidad de mejorar la salud de personas con problemas con problemas digestivos y diabetes en Colombia. Por lo anterior se planteó el aprovechamiento de los beneficios de este tubérculo, que se cultiva en la región andina, ya que contiene prebióticos como son la inulina y fructooligosacárido (azúcares naturales) conocidos también como FOS. El cuerpo humano no puede digerir estos compuestos, pero al consumirlos ayudan al sistema digestivo y fortalece el sistema inmunológico. Una alternativa para dar un uso diferente a este tubérculo es crear un producto tipo edulcorante con contenido de fibra y bajos en calorías que sean aptos para diabéticos y personas que sufran problemas digestivos. Este producto podría ser comercializado de forma exitosa al interior del país Para la ejecución del proyecto de investigación se desarrollaron tres fases: Fase 1: se realizó la caracterización fisicoquímica del yacón y determinaron los beneficios de los prebióticos (inulina y fructooligosacáridos) presentes en él. Fase 2: se realizó el proceso de extracción de los prebióticos. Fase 3: se estableció la forma de industrializar y aprovechar los prebióticos (inulina y los fructooligosacáridos) que se encuentran en el Yacón. Esta investigación se caracterizó por ser de tipo mixto (exploratorio, descriptivo, experimental y correlacional), inicialmente la investigación inició como exploratoria y fue transformándose a medida que avanzó la investigación en descriptiva, experimental y correlacional. Las técnicas utilizadas fueron de observación, experimental y documental. Como resultados y conclusiones determinamos la composición fisicoquímica del yacón analizando el porcentaje de materia seca, humedad, azucares reductores y fibra, evidenciándose que estos parámetros se encontraban dentro de los rangos establecidos por estudios realizados por diferentes autores. Por otra parte por el método de extracción del secado se determinó que se pueden obtener los prebióticos contenidos en el yacón como son la inulina y los fructooligosacáridos y además se pudo determinar a través de otras técnicas a nivel industrial como son el ultrasonido, la hidrólisis ácida, el secado y pulverizado de la materia prima (yacón) se pueden obtener los prebióticos presentes en el yacón (inulina y los fructooligosacáridos) como edulcorantes y fibra presentes.
PCAT-DE: Reconstructing Pointlike and Diffuse Signals in Astronomical Images Using Spatial and Spectral Information
Authors: Feder Richard M. , Butler Victoria , Daylan Tansu , Portillo Stephen K. N. , Sayers Jack , Vaughan Benjamin J. , Zamora Catalina V. , Zemcov Michael 
Published: August 2023

Abstract
Observational data from astronomical imaging surveys contain information about a variety of source populations and environments, and their complexity will increase substantially as telescopes become more sensitive. Even for existing observations, measuring the correlations between pointlike and diffuse emission can be crucial to correctly inferring the properties of any individual component. For this task, information is typically lost, because of conservative data cuts, aggressive filtering, or incomplete treatment of contaminated data. We present the code PCAT-DE, an extension of probabilistic cataloging, designed to simultaneously model pointlike and diffuse signals. This work incorporates both explicit spatial templates and a set of nonparametric Fourier component templates into a forward model of astronomical images, reducing the number of processing steps applied to the observed data. Using synthetic Herschel-SPIRE multiband observations, we demonstrate that point-source and diffuse emission can be reliably separated and measured. We present two applications of this model. For the first, we perform point-source detection/photometry in the presence of galactic cirrus and demonstrate that cosmic infrared background galaxy counts can be recovered in cases of significant contamination. In the second, we show that the spatially extended thermal Sunyaev–Zel’dovich effect signal can be reliably measured even when it is subdominant to the pointlike emission from individual galaxies.
A Large Magnetic Hump in the VLISM Observed by Voyager 1 in 2020–2022
Authors: Burlaga L. F. , Pogorelov N. , Jian L. K. , Park J. , Szabo A. , Ness N. F. 
Published: August 2023

Abstract
Voyager 1 has been moving through the very local interstellar medium (VLISM) for approximately one solar cycle, from 122.58 au on 2012/DOY 238 (August 25) to 158.5 au on 2023.0. Previously, an abrupt increase (“jump”) in the magnetic field strength B and proton density N by a factor of 1.35 and 1.36, respectively, was observed during an interval of ∼8 days in 2020.40. After the jump, B continued to increase to a maximum value ∼0.56 nT at ∼2021.4 and then declined until B returned to the postjump value of 0.5 nT on 2021.85, 1.45 yr after the jump. The magnetic field strength declined briefly from 0.5 nT on 2021.85 to 0.47 nT on 2021.95 and then increased sporadically to 0.52 nT at 2023.0. Thus, the magnetic field strength remained strong for at least 2.6 yr. The magnetic hump and the density hump were a compression wave propagating through the VLISM. The compression wave was generated by a region with large dynamic pressure in the solar wind that propagated through the inner heliosheath and collided with the heliopause. The magnetic field strength continued to remain strong, with slow variations, until the end of our observations at 2023.0. It is suggested that the magnetic hump evolved from the large dynamic pressure, high speeds, and density observed at 1 au between ∼2015 and ∼2017.
Near-infrared Spectroscopy of Dense Ejecta Knots in the Outer Eastern Area of the Cassiopeia A Supernova Remnant
Authors: Koo Bon-Chul , Lee Yong-Hyun , Lee Jae-Joon , Yoon Sung-Chul 
Published: August 2023

Abstract
The Cassiopeia A supernova remnant has a complex structure, manifesting the multidimensional nature of core-collapse supernova explosions. To further understand this, we carried out near-infrared multiobject spectroscopy on the ejecta knots located in the northeastern (NE) jet and Fe K plume regions, which are two distinct features in the outer eastern area of the remnant. Our study reveals that the knots exhibit varying ratios of [S ii] 1.03, [P ii] 1.189, and [Fe ii] 1.257 μm lines depending on their locations within the remnant, suggesting regional differences in elemental composition. Notably, the knots in the NE jet are mostly S-rich with weak or no [P ii] lines, implying that they originated below the explosive Ne-burning layer, consistent with the results of previous studies. We detected no ejecta knots exhibiting only [Fe ii] lines in the NE jet area that are expected in the jet-driven supernova explosion model. Instead, we discovered a dozen Fe-rich knots in the Fe K plume area. We propose that they are dense knots produced by a complete Si burning with α-rich freeze-out in the innermost region of the progenitor and ejected with the diffuse X-ray-emitting Fe ejecta but decoupled after crossing the reverse shock. In addition to these metal-rich ejecta knots, several knots emitting only He i 1.083 μm lines were detected, and their origin remains unclear. We also detected three extended H emission features of circumstellar or interstellar origin in this area and discuss their association with the supernova remnant.
The Spectacular Tidal Tails of Globular Cluster M3 (NGC 5272)
Authors: Yang Yong , Zhao Jing-Kun , Tang Xin-Zhe , Ye Xian-Hao , Zhao Gang 
Published: August 2023

Abstract
We provide a detailed analysis of the tidal tails of the globular cluster M3 (NGC 5272). We first discover clear extratidal structures with a slight S shape near the cluster. This inspires us to examine the existence of its long tidal tails. We highlight potential stream stars using the proper motions (PMs) of a model stream combined with the cluster’s locus in a color–magnitude diagram (CMD). A 35° long leading tail and a 21° long trailing tail are successfully detected at the same time. Their corresponding overdensities can be recognized in CMD and PM space after subtracting the background. We estimate the stream width, star number density, and surface brightness for both tails, as well as the distance variation along the entire stream. We then verify the connection of M3 and the Svöl stream. Finally, we tabulate 11 member stars belonging to the M3 tidal stream with available spectroscopic observations.
The X-Ray Binary-star Cluster Connection in Late-type Galaxies
Authors: Hunt Qiana , Chandar Rupali , Gallo Elena , Floyd Matthew , Maccarone Thomas J. , Thilker David A. 
Published: August 2023

Abstract
We conduct one of the largest systematic investigations of bright X-ray binaries (XRBs) in both young star clusters and ancient globular clusters (GCs) using a sample of six nearby star-forming galaxies. Combining complete CXO X-ray source catalogs with optical Physics at High Angular Resolution in Nearby Galaxies-Hubble Space Telescope cluster catalogs, we identify a population of 33 XRBs within or near their parent clusters. We find that GCs that host XRBs in spiral galaxies appear to be brighter, more compact, denser, and more massive than the general GC population. However, these XRB hosts do not appear to be preferentially redder or more metal-rich, pointing to a possible absence of the metallicity-boosted formation of low-mass X-ray binaries (LMXBs) that is observed in the GCs of older galaxies. We also find that a smaller fraction of LMXBs is found in spiral GC systems when compared with those in early-type galaxies: between 8% and 50%, or an average of 20% across galaxies in our sample. Although there is a non-negligible probability of a chance superposition between an XRB and an unrelated young cluster, we find that among clusters younger than 10 Myr, which most likely host high-mass XRBs, the fraction of clusters associated with an XRB increases at higher cluster masses and densities. The X-ray luminosity of XRBs appears to increase with the mass of the cluster host for clusters younger than ∼400 Myr, while the inverse relation is found for XRBs in GCs.
Joint Action and Competition between Centrifugal, Magnetorotational, and Magnetic Buoyancy Instabilities
Authors: Gradzki M. J. , Hughes D. W. , Mizerski K. A. 
Published: August 2023

Abstract
Instabilities driven by some combination of rotation, velocity shear, and magnetic field in a stratified fluid under gravity play an important role in many astrophysical settings. Of particular note are the centrifugal instability, the magnetorotational instability, and magnetic buoyancy instability. Here, we consider a Cartesian model of an equatorial region incorporating all the physical ingredients necessary to study their competition. We investigate the linear instability to interchange (“axisymmetric”) modes of an inviscid, perfectly conducting, isothermal gas, including the effects of rotation, velocity shear, and poloidal and toroidal magnetic fields. The stability problem can be reduced to a second-order boundary value problem, with the growth rate as the eigenvalue. We can make analytic progress through consideration of the physically relevant regime in which the transverse horizontal wavenumber k ≫ 1. Via a perturbation analysis, with 1/k as the small parameter, we can derive the growth rate and the spatial dependence of the eigenfunctions: the unstable modes are strongly localized in the vertical direction, being either wall modes (localized near a boundary of the domain) or body modes (localized in the interior). We describe the conditions under which the joint action of the separate instability mechanisms leads to enhancement or suppression of the instability. Our analytical results are supplemented by numerical solutions of the stability problem. The most unstable mode found analytically is typically in excellent agreement with that found numerically through consideration of a wide range of wavenumbers. Finally, we discuss how our results relate to the solar tachocline.
Investigating the Impact of Metallicity on Star Formation in the Outer Galaxy. I. VLT/KMOS Survey of Young Stellar Objects in Canis Major
Authors: Itrich Dominika , Karska Agata , Sewiło Marta , Kristensen Lars E. , Herczeg Gregory J. , Ramsay Suzanne , Fischer William J. , Tabone Benoît , Rocha Will R. M. , Koprowski Maciej , Lê Ngân , Deka-Szymankiewicz Beata 
Published: August 2023

Abstract
The effects of metallicity on the evolution of protoplanetary disks may be studied in the outer Galaxy where the metallicity is lower than in the solar neighborhood. We present the VLT/KMOS integral field spectroscopy in the near-infrared of ∼120 candidate young stellar objects (YSOs) in the CMa-ℓ224 star-forming region located at a Galactocentric distance of 9.1 kpc. We characterize the YSO accretion luminosities and accretion rates using the hydrogen Brγ emission and find a median accretion luminosity of

log
(

L

acc

)
=
−

0.82

−
0.82

+
0.80

L

⊙

. Based on the measured accretion luminosities, we investigate the hypothesis of star formation history in the CMa-ℓ224. Their median values suggest that Cluster C, where most of YSO candidates have been identified, might be the most evolved part of the region. The accretion luminosities are similar to those observed toward low-mass YSOs in the Perseus and Orion molecular clouds, and they do not reveal the impact of lower metallicity. Similar studies in other outer Galaxy clouds covering a wide range of metallicities are critical to gain a complete picture of star formation in the Galaxy.
Non-LTE Abundances of Helium, Magnesium, and Silicon in the Atmosphere of the Bp He-weak Star HD 175156
Authors: Monier Richard 
Published: August 2023

Abstract
The synthesis of the spectral range 4400–4600 Å in UVES spectra of HD 175156 allows to estimate NLTE abundances of helium, nitrogen, oxygen, magnesium and silicon for this evolved B subgiant. The NLTE models used are published models from the BSTAR grid. Compared to the solar abundances, helium and magnesium are found to be overabundant by a factor of 2.0, oxygen and silicon underabundant by a factor of 0.75. Nitrogen has a solar abundance. The overabundances of helium and magnesium are reduced compared to their determinations in Local Thermodynamical Equilibrium.
Association of HPV Genotyping with HIF1-Alpha in Advanced Cervical Cancer on Response to Radiotherapy
Authors: Anfasa Muhammad Khalif , Suardi Dodi , Salima Siti , Winarno Gatot Nyarumenteng Adhipurnawan , Dewayani Birgitta Maria , Trianasari Nurvita , Sahiratmadja Edhyana 
Published: August 2023

AIM: This study aims to determine the relationship between the HPV genotype in uterine cervical cancer and the expression of HIF-1α due to tissue hypoxia and its impact on radiation response.
METHODS: This study is an analytic and observational study with a cross-sectional design with the inclusion criteria in this study that was new cervical cancer Stage IIB, IIIA, IIIB, and IVA patients treated at the oncology polyclinic who had never undergone radiotherapy and would be treated with radiation.
RESULTS: Sixty patients advanced cervical cancer aged 25 to >45 years were involved patients. The majority had HPV genotype 16 infections. There was no significant relationship between treatment response and HPV genotype (HPV 16 genotype [p = 0.844], HPV 18 genotype [p = 0.161], other HPV genotypes [p = 0.108]), radiation response with HIF-1α expression (p = 0.503; OR 1.569 [0.417–5.899]), HIF1α expression with HPV genotype (HPV genotype 16 (p = 0.648; OR 1,357 [0.356–5.041]), HPV 18 genotype (p = 0.344; OR 1,458 [0.089–2.373]), and other HPV genotypes (p = 0.505; OR 1.667 [0.368–7.553]) as well as HIF-1α expression and HPV genotypes to radiation response (p > 0.05).
CONCLUSION: Cervical cancer with infection with HPV Genotype 18 tends to express HIF1α strongly and increased partial radiation response. Overall statistically, there was no significant association between infection with certain genotypes of HPV with radiation response or HIF-1α expression in tumor tissue with radiation response.
Capturing and Using Taxonomic Knowledge for Species Identification
Authors: Koch Wouter 
Published: August 2023

The skills and knowledge needed to recognize and classify taxa are becoming increasingly scarce in the scientific community, resulting in a “taxonomic impediment”, where such knowledge is gradually disappearing (Engel et al. 2021). At the same time, it is clear that these skills are strongly needed in biodiversity monitoring for management and conservation, especially when carried out by citizen scientists. Formalizing the knowledge required to distinguish taxa from one another in the form of open digital identification keys is one way of making such knowledge more findable, accessible, interoperable and reusable (FAIR) for professional and amateur observers of biodiversity.
Experience working with taxonomic experts to capture taxonomic knowledge in a tabular, multiple access format has proven that important nuances in taxonomic knowledge cannot be captured in a tabular format in a practical manner. Features like taxonomic hierarchy, rich metadata, formalized geographical scope, multilingualism, numerical ranges, logical premises, and links to external services are all much needed improvements of digital identification keys. However, these are complex to capture in a tabular format, defeating the benefits of its general simplicity. To address this, we have developed Clavis, an open format for identification keys written in JavaScript Object Notation (Koch et al. 2022). The goal is to create an ecosystem where different implementations and mappings of the Clavis format can serve the needs of various users and institutions, while maintaining knowledge exchange.
Having a versatile format as a foundation, a crucial next step was to offer experts a tool to edit and test identification keys, and provide end-users with a tool to access this information. In this presentation, we show the Clavis format itself, as well as an online editing tool and a end-user interface, available on clavis.no. Providing a more advanced use case, we demonstrate how we implement Clavis in tandem with computer vision, providing users with a single tool to quickly and reliably identify taxa using different technologies.
“Finding My Place in Academia”: Understanding the Experiences of Novice Faculty
Authors: McPherson Sara , Wendler M. Cecilia 
Published: August 2023

Background:
The current nursing faculty shortage rapidly has expanded the need to hire faculty. New faculty are clinical experts in their own practice; however, many lack formal knowledge about the academic setting, making the transition from practice to academia difficult.

Method:
A qualitative descriptive study was developed to identify how new faculty transition into their academic positions. The sample consisted of 12 clinical nursing faculty participants.

Results:
A total of 12 themes emerged: awful day as faculty, career plans, compensation, finding my place in academia, great day at clinical, “I wanted to be successful,” preparation for the faculty role, struggling, student experiences, support, lack of support, and surprise. Finding ways to recruit and retain qualified faculty is imperative.

Conclusion:

Inadequate support for transitioning to the faculty role may contribute to faculty turnover; developing a strong mentoring program may help retain qualified faculty.

[
J Nurs Educ
. 2023;62(8):433–442.]
Synthetic glycovaccines elicit cross-protection against Chagas disease and tegumentary leishmaniasis in a murine co-infection model
Authors: Knight Colin D , Estevao Igor L , Portillo Susana , Farani Priscilla Silva Grijo , Montoya Alba , Heydemann Emily , Carvajal Elisa G , Vinales Irodiel , Gil Eileni R , Rodriguez Felipe , Maldonado Rosa A , Michael Katja , Almeida Igor C 
Published: August 2023

Abstract
Chagas disease (CD) and tegumentary leishmaniasis (TL) are two of the World Health Organization’s (WHO) top 20 neglected tropical diseases. These diseases are caused by the protozoan trypanosomatids, Trypanosoma cruzi and Leishmania spp., respectively. Although historically restricted to Central and South American, there are currently, ~7 million people infected with CD worldwide, with ~300,000 chronically infected patients in the US. Between 700,000 and 1.2 million new cases of TL occur worldwide yearly. Chemotherapeutic agents are available for the treatment of both diseases; however, they may cause serious adverse events, ultimately resulting in premature treatment interruption. Moreover, no effective vaccine for either disease is currently available. Due to the evolutionary loss of the α1,3-galactosyltransferase (α1,3GT) gene in humans and Old-World nonhuman primates, α-Gal epitopes, abundantly expressed on both Trypanosoma cruzi and Leishmania spp. cell surfaces, are highly immunogenic. We, therefore, hypothesize that a synthetic glycan-based vaccine could provide effective cross-protection against a T. cruzi and L. major co-infection. Here we use an α1,3GT-knockout (α1,3GT-KO) murine model to evaluate the efficacy of two new synthetic neoglycoproteins, NGP28b and NGP29b, containing nonreducing, terminal α-Gal and β-Galf glycotopes, respectively, as potential vaccine candidates against CD and TL. Our data indicate that both vaccine candidates induce a strong cross-protective immune response, significantly reducing parasite burden and increasing animal survival in this co-infection experimental model
This study was partially supported by a grant NIH-U54MD007592 (to Robert A. Kirken (PI), ICA (Co-I)), from the National Institute on Minority Health and Health Disparities (NIMHD). We would like to thank the staff of the Border Biomedical Research Center (BBRC) Biomolecule Analysis Omics Unit (BAOU). BAOU was supported by the NIMHD grant 5U54MD007592. CDK was supported by the UT System LSAMP program which is funded by the National Science Foundation grant number HRD-1202008.