bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study of fine needle aspiration cytology findings with thyroid function test, anti-thyroid antibody, and clinical pathological parameters in cases of chronic lymphocytic thyroiditis
Authors: Marachapu Jahnavi , Vij Swati 
Published: March 2023

: Chronic lymphocytic thyroiditis is autoimmune thyroiditis; it is considered as second most common thyroid disorder diagnosed on FNAC following colloid goitre. FNAC is a reliable and efficient method for diagnosing these thyroid lesions. Chronic Lymphocytic thyroiditis frequently affects women, primarily compared to men and is commonly found with hypothyroidism, euthyroidism or every so often with hyperthyroidism. The incidence rate of Hashimoto’s thyroiditis is 1–4%, with an occurrence of 30–60/100000 population per year. Autoimmune thyroiditis can be categorised on the cytomorphological features of FNAC. To compare FNAC cytological findings with TFT in Chronic lymphocytic thyroiditis. One hundred ten patients with thyroid swellings were presented for FNAC examination, serology of TFT and Anti TPO antibodies and Ultrasonography during 2020–2021. In addition, fine needle aspiration cytology was performed using non-aspiration or aspiration techniques. TFT and Anti- TPO antibodies were performed on Avion CLX 120 auto analyser based on the Chemiluminescence method. Out of 110 cases of midline neck swelling presented in our department, Autoimmune Thyroiditis was observed in 43 cases. The most affected age group of lymphocytic thyroiditis was 21–30 years, with the male: female ratio being 1:3. Most of the patients presented with diffuse swelling and few presented with nodular swelling. The Grading of the lymphocytic thyroiditis was done by the criteria used by Bhatia et al Anti-TPO antibody was elevated in 19 cases (26.2%), and TSH was elevated in 28 cases (40.81%). These cases were diagnosed as autoimmune thyroiditis on cytology, clinically and also correlating with radiological findings. Grade 3 lymphoid infiltrate was seen in 53.33% (16/30) cases, and Grade 2, lymphoid infiltrate was seen in eight cases (62.50%). Grade 1 lymphoid infiltrate was seen in five cases (11.63%). Among 43 cases, 28 cases (65.12%) show hypothyroidism, 7 cases (16.28%) show hyper, and 8 cases (18.60%) show Euthyroidism. Among these 43 cases, 26 cases showed diffuse thyroid swelling on ultrasonography, and 7 cases showed solitary nodule. Grade 3 lymphocytic infiltration statistically correlates with anti-TPO and TSH in conjunction with ultrasonography findings of diffuse enlargement of the thyroid gland. The presence of Hurthle cell change, giant cells, anisonucleosus, and granulomas do not find to be any statistical correlation with lymphocytic thyroiditis as these cases are primarily corresponding to Grade 1 and Grade 2. Through this study, we conclude that FNAC remains the gold standard method despite having different diagnostic modalities accessible for diagnosing thyroid lesions. Grading of FNAC Smears depends on lymphocytic infiltration of the thyroid follicles, along with positivity for antithyroid antibodies (anti-TPO antibody) and TSH. These findings are firmly associated with Chronic Lymphocytic Thyroiditis.
Accuracy of different cytoarchitectural features in the diagnosis of papillary thyroid carcinoma by fine needle aspiration
Authors: Malhasi I W G A L , Fernando C S , de Silva MVC 
Published: March 2023

Fine needle aspiration (FNA) has about 90% diagnostic accuracy for papillary thyroid carcinoma (PTC) in an adequate sample. Ignorance of relative significance of individual cytologic features may lead to misdiagnosis due to reliance on a single or few features. Our objective was to determine the usefulness of individual and most appropriate combined cytologic features, for diagnosis of PTC. H&E stained FNA smears of fifty cases each, of consecutive histologically confirmed PTC and benign thyroid cases (controls), reported over 3 years, were retrieved from the files. A total of 31 architectural, cytological and background features were assessed, blind to the final diagnosis and compared amongst the two groups. The statistical significance (p&#60;0.05) of each parameter was determined by chi-square and odds ratio and combinations quality assessed by ROC curves.: Twenty features were found to be statistically significant. Fourteen highly significant (p&#60;0.000) features included flat syncytial sheets, anatomical borders, true papillae, cellular swirls, individually dispersed cells with eosinophilic cytoplasm, anisonucleosis, elongated oval nuclei, powdery chromatin, nuclear outline irregularity, thickened nuclear membranes, crescent shaped nuclei, intranuclear inclusions, histocytoid cells and soap bubble cytoplasmic vacuolation. The six statistically significant features (p&#60;0.05) included micro-acinar structures, cellular crowding, nuclear overlapping, nuclear grooves, squamoid cells and bubble gum colloid. The control group also showed some of these single cytologic features. All the combinations of ≥ 4 features had a statistical significance of p=0.000 and specificity and PPV of 100% with ROC showing excellent results. Using correct combination of cytologic features will increase accuracy of FNA diagnosis of PTC.
An unexpected finding of bone marrow metastasis from adenocarcinoma of lower gastrointestinal tract origin: Case report
Authors: Sharma Saket , Makwana Jhanvi , Kaka Riya , Mandal Moushumi 
Published: March 2023

Bone marrow examination is an essential tool for diagnosis of many diseases including both hematological and non hematological tumors. Bone marrow is commonly involved by many metastatic solid tumors. Bone marrow aspirates, and biopsies have been found to be more useful than radiological investigations in early diagnosis of bone marrow metastasis.Here we present a case of a 75 years old male patient presenting with acute sudden onset chest pain along with multiple lytic sclerotic foci in lumbar vertebrae, bilateral ribs, clavicle, scapula and sternum along with fractures in multiple ribs. CBC findings showed anemia with thrombocytopenia. Bone marrow examination revealed an infiltration of a metastatic tumor in bone marrow which was further confirmed to be of lower gastrointestinal tract in origin on IHC findings.A high suspicion for bone marrow metastasis should be considered in cases who present primarily with abnormalities in peripheral blood count and a vigilant search for metastatic cells on aspirate smears and imprint smears can help in early diagnosis of bone marrow metastasis by solid tumors.
Cytodiagnosis of multilobulated aggressive angiomyxoma clinically mimicking sarcoma – A case report
Authors: Phukan Neeharika , Devi Junu 
Published: March 2023

: Aggressive angiomyxoma is a rare but locally aggressive infiltrative mesenchymal tumour arising in the soft tissues of the lower genital tract. Incidence is very less (only about 350 cases have been recorded in the literature) with female to male ratio of 6:1. Average age at presentation is around 40 years.: A 32 years old female presented with multiple swelling in the vulval region for 1 and a half years associated with mild pain. The patient complains of dysmenorrhoea, pressure sensation, pelvic fullness, dyspepsia, weight loss and generalised weakness. She is married and has a 3-year old male child. Her menstrual cycle is regular with normal menses. FNAC of the vulval swelling was suggestive of angiomyxoma. The swelling was excised in the Gynaecological Operation Theatre and the specimen was sent to the Department of Pathology for Histopathological examination where it was diagnosed as aggressive angiomyxoma. On follow up, the patient was healthy with no complains of recurrence so far. : Aggressive angiomyxoma is an aggressive tumour because it has a high risk of infiltration and local recurrence. Therefore, it should be distinguished from other myxoid tumours. Preoperative cytological diagnosis helps in surgical management with appropriate wide local excision with clear margins.
Giant retroperitoneal dedifferentiated liposarcoma - A rare case report
Authors: Palaniraj S , Gopu G , Jayanthi Bharathi Vidhya 
Published: March 2023

Retroperitoneal liposarcomas are uncommon malignancy accounting for 0.15% of all malignancies. The overall survival and prognosis is predominantly based on the total completeness of resection i.e. margin status and the histopathologic grade of the tumour. The retroperitoneal sarcomas usually present late in the disease course and often develops local invasion of the vital structures at the time of clinical presentation which makes resection with clear margins difficult and challenging. Here we present a case of Giant dedifferentiated liposarcoma arising from retroperitoneum.
Myoid hamartoma of breast clinically masquadering as phyllodes tumor- A rare case report
Authors: Varma Kachnar , Tripathi Sonal , Sharma Neha , Misra Vatsala 
Published: March 2023

Mammary hamartoma (MH) is an infrequent form of breast tumor that accounts for approximately 4.8% of all benign breast lesions. Myoid (muscular) hamartomas are uncommon benign breast lesions that are considered to be a variant of mammary hamartomas. Since the pathogenesis of MH is poorly understood, its true incidence is under-reported by clinicians and as well as pathologists.Thus, we report this case of MH in a middle-aged female, who presented with a large breast mass mimicking phyllodes tumor and giant fibroadenoma, however, histopathology and immunohistochemical examination aided its diagnosis as Myoid Hamartoma. We present this case to highlight this rare benign breast lesion.
Total Sleep Deprivation Reduces Quality of Spermatozoa in Male Albino Rat (Rattus norvegicus)
Authors: Arjadi Fitranto , Wisesa Sindhu , Indriani Vitasari 
Published: March 2023

Abstract: Sleep deprivation-induced stress decreases the quality of spermatozoa due to the increase of glucocorticoid levels through the hypothalamic-pituitary-adrenal axis. Sleep recovery (SR) restores the effect of stress due to sleep deprivation by decreasing lipid peroxides and other free radicals and increasing glutathione antioxidants. This study aims to determine the spermatozoa quality in male albino rats (Rattus norvegicus) after the stress induction by diverse sleep deprivation protocols. This study is experimental research with posttest-only control group design in 30 male albino rats divided into five groups consisting of group I for negative control (no induction of sleep deprivation), group II for paradoxical sleep deprivation (PSD), group III for total sleep deprivation (TSD), group IV for PSD followed by SR, and group V for TSD followed by SR. PSD and TSD were performed by depriving rats sleep for 20 and 24 hours/day, respectively, for five days. SR was done for the next five days after PSD or TSD. Shapiro-Wilk test was used for normality of data distribution, and Levene's test was used for variance homogeneity. Comparative hypothesis was then analyzed with One Way Analysis of Variance (ANOVA) test, and significance between groups was analyzed with Tukey's Post-Hoc test. Group III (TSD) demonstrated the lowest mean of spermatozoa count (41,53±2,29), spermatozoa morphology (13,00±2,91), spermatozoa viability (31,00±7,39), and percentage of motility rate (37±8,58%) among all groups. In conclusion, total sleep deprivation (TSD) decreases the quality of spermatozoa in male albino rats (Rattus norvegicus).
Identification Risk Factors of Stroke: Literature Review
Authors: Agianto Agianto , Yulise Bellia , Agustina Rismia , Rizany Ichsan 
Published: March 2023

Abstract: State spending to deal with stroke is quite large every year due to the high incidence of stroke. Data from the Ministry of Health of Indonesia mentions an increasing number in health financing every year, the country financed stroke services by 2.56 trillion in 2018. The magnitude of the incidence of stroke can be lowered by controlling the risk factors of stroke. This study aimed to identify stroke risk factors, both those modifiable risk factors and irreversible risk factors. Research is conducted with a literature review using descriptive study methods or correlation analysis with cross sectional approaches. Sixteen articles identified from Google scholars and Garuda databases in the 2015-2020 range, and were analysed using JBI critical appraisal tools-checklist for analytical cross-sectional studies and JBI critical appraisal tools-checklist for prevalence studies. Synthesis narrative was used to analyse the articles. Out of 16 articles examined the modifiable risk factors were hypertension, dyslipidemia, diabetes mellitus, lack of physical activity, blood sugar levels, cholesterol levels in blood, alcohol and drug consumption, kidney disease, tuberculosis, heart disease, heart failure, obesity, central obesity, atrial fibrillation and also smoking are declared associated with the incidence of stroke. The irreversible risk factors are age, gender, education, family history, income employment, previous stroke history, and rural and urban distribution. Risk factors divided into two categories modifiable risk factors and irreversible risk factors. It is important to know the risk factors of stroke in order prevent the occurrence of stroke as early as possible by avoiding modifiable stroke risk factors. Hypertension, smoking, diabetes mellitus obesity, dyslipidemia, and lack of activity are the most modifiable stroke risk factors identified in the articles. The most irreversible risk factors identified in the article are age, gender, and level of education.
TINGKAT KESIAPSIAGAAN MASYARAKAT TERHADAP BENCANA TANAH LONGSOR DI WILAYAH KABUPATEN MADUKARA BANJARNEGARA TAHUN 2018
Authors: Ridwanulloh Muhammad 
Published: March 2023

Penelitian ini dilakukan (1) Untuk mengetahui tingkat kerentanan bencana tanah longsor di Kecamatan madukara. (2) Untuk mengetahui kesiapsiagaan masyarakat terhadap bencana tanah longsor di Kecamatan Madukara. (3) Untuk mengetahui bagaimana penguranagan resiko bencana tanah longsor berbasis masyarakat di Kecamatan Madukara. Bentuk penelitian yang dilakukan adalah penelitian kualitatif menggunakan metode sempling dan surve. Teknik uji validitas data menggunakan triangulasi data, observasi lapangan, serta penggunaan data interpretasi dan data sekunder. Hasil penelitian tersebut adalah (1) tingkat kerentanan bencana tana longsor di Kecamatan madukara trdapat 20 desa yang di bagi menjadi 3 kreteria rendah dengan jumlah 4, sedang 7 desa, tinggi 9 desa. (2) Pada kategori kurang siap individu dan rumah tangga mereka mengetahui bencana tanah longsor namun masih sangat terbatas. kategori hampir siap individu sudah menegtahui dan mmemahami bencana tanah longsor dalam sekala yang terbatas. kategori siap individu dan rumah tangga sudah memahami dan mengetahui resiko bencana yang ada namun belum maksimal. (3) pelatihan kesiapsiaan bencana, pemasagan rambu jalur efakuasi, pemasangan alat peringatan bencana serta reboisasi pada darah rentan bencana tanah longsor bisa menjadi solusi.
PENYELARASAN KURIKULUM SMK KOMPETENSI KEAHLIAN TEKNIK KENDARAAN RINGAN OTOMOTIF DENGAN KOMPETENSI INDUSTRI
Authors: Mahendra Andhika Cahya , Ranto Ranto , Towip Towip 
Published: March 2023

<p>The development of this fast era makes competition to get a job to increase and become more difficult. In the current competition in the industrial world, it demands an increase in the quality of Human Resources through education. Vocational High School Education also prepares its graduates to go directly into the world of industry, but there are still limitations between the need for human resources in industry and the human resources produced by educational institutions. So therefore<strong> </strong>Curriculum development in Vocational High Schools is developed by prioritizing the needs of society, one of which is the need to be able to compete directly in industry. The aims of this research are: (1) To find out the alignment process between the SMK curriculum and industry. (2) Knowing how far the curriculum in SMK is aligned with the world of work in industry. (3) Knowing whether the SMK curriculum with industry is feasible. The method used in the automotive concentration curriculum alignment activities at SMKs uses a qualitative approach with descriptive research. Data collection techniques using techniquespupose sampling. Data collection techniques in this study used data collection techniques in the form of interviews, documents, and observations. The research documents include the Merdeka Curriculum, K13 Curriculum, service books, vehicle inspection sheets, and the results of the FGD minutes. Data analysis techniques in this study used content analysis techniques (analysis content). The research locations were limited to 2 SMK, namely: SMKN 2 Surakarta and SMK Warga Surakarta and three industries, namely: Toyota Nasmoco Ringroad, Daihatsu Adi Sucipto, and Suzuki Pabelan (PT. Solo Indonesia Utama). The data obtained is then juxtaposed between the curriculum and competencies in the industry in tabular form so that it can be seen which curriculum and competencies are not aligned. The results of this study are: The curriculum between automotive engineering vocational schools and industrial competencies is aligned, this is evidenced by the existenceforum grub discussion (FGD) between the SMK and the automotive industry.<em></em></p>
Boosting human capacities: How vaccination behavior and intention relates to attitudes toward vaccination, Human Enhancement, and naturalness
Authors: Döbler Niklas Alexander , Carbon Claus-Christian 
Published: March 2023

Abstract
Background: Even if vaccinations are widely available, a considerable number of people reject them. As sophisticated biotechnologies capable of augmenting the human body's capacities, vaccinations are an instance of Human Enhancement (HE): The effort to use technologies to improve humans. Global vaccination efforts against SARS-CoV-2 evoke public concerns similar to those in the general HE debate, namely, naturalness and invasiveness. We explore these variables and their connection to vaccination behavior in the context of the COVID-19 pandemic.
Methods: We conducted an online survey (N = 314 persons) with 256 participants (81.5%) vaccinated against SARS-CoV-2 and n = 58 (18.5%) not vaccinated. Participants answered questions concerning their attitudes on nature and naturalness, willingness to use cognitive enhancement methods, HE, psychological effects of vaccination, and planned vaccination. Several Bayesian regression models were constructed to predict the willingness to use cognitive enhancement, attitudes toward vaccinations and HE, and whether people plan for further vaccination doses.
Results: Participants were more willing to use methods to improve cognitive abilities if considered natural, non-invasive, and not used frequently. A less affirmative attitude toward naturalness was also associated with more willingness to use. Effects were primarily moderated by vaccination status. Vaccinated and unvaccinated participants differed substantially, especially in measures that reflected the attitude toward naturalness and related phenomena. Participants did not assess vaccinations as a prime example of HE. Rating of vaccination as enhancement did not reliably predict attitude on vaccination nor HE. More affirmative attitudes toward naturalness and not being vaccinated were negatively associated with the attitude toward vaccinations and HE. A positive attitude toward HE predicted a more positive attitude toward vaccinations. Support of disease control measures and attitude toward vaccinations positively predicted vaccination intention. Receiving the vaccination led to psychological relief.
Conclusions: Motives of vaccination and HE refusal appear to be linked. Interventions considered unnatural and invasive are deemed unfavorable. These reasons seem more pronounced for unvaccinated participants. If HE, e.g., vaccination, constitutes an essential public health measure, concerns about the human relationship to nature, perceived naturalness, and sanctity of the human body must be sufficiently and thoughtfully addressed.
Non-contact human presence sensing technology based on WiFi signal
Authors: Xuechun Wang , Jinghao Wen 
Published: March 2023

Abstract
With the rapid development of Internet of things technology, people’s demand for adaptive non-contact sensing is growing. Aiming at the problems of traditional human perception technologies such as vision-based, poor sensor universality, and low accuracy, this paper proposes a new non-contact human presence perception technology based on WiFi, which sequentially preprocesses, extracts features, and classifies the collected channel state information, and establishes signal models corresponding to different states to realize human perception and recognition. Experiments show that the sensing accuracy of this method is high, up to 99 % , and it can be well applied in smart homes, medical care, and other life scenes.
Feminization of the health workforce in China: exploring gendered composition from 2002 to 2020
Authors: Li Mingyue , Raven Joanna , Liu Xiaoyun 
Published: March 2023

Abstract
Background
Feminization and gender diversity of the health workforce has been global documented and has stimulated wide discussion, but it has not been investigated in China. This study aims to analyze the change of the gendered composition of health workforce, and explore the trend in different professions and different health organizations within China’s hierarchical health system.
Methods
The data were collected from China Health Statistical Yearbook from 2002 to 2020. We focused on health professionals, doctors, nurses, pharmacists, and management staff in health organizations. Trend analysis was employed to examine the change in the ratio of female health workforce over 18 years. The estimated average annual percent change (AAPC) was estimated, and the reciprocals of variances for the female ratios were used as weights.
Results
The number of health professionals in China increased from 4.7 million in 2002 to 10.68 million in 2020. The number of health professionals per 1000 population increased from 3.41 in 2002 to 7.57 in 2020. The ratio of female health professionals significantly increased from 63.85% in 2002 to 72.4% in 2020 (AAPC=1.04%, 95%CI 0.96%-1.11%, P<0.001). Female doctors, pharmacists, and management staff increased 4.7, 7.9 and 3.5 percentage points from 2002 to 2020, respectively. Female health workers at township health centers, village clinics, centers for disease control and prevention had higher annual increase rate (AAPC=1.67%, 2.25% and 1.33% respectively) than those at hospital (0.70%) and community health center (0.5%). Female doctors in traditional Chinese medicine, dentistry and public health had higher annual increase rate (AAPC=1.82%, 1.53% and 1.91% respectively) than female clinical doctor (0.64%).
Conclusions
China’s health workforce is mainly composed of women, and has been feminizing steadily over the last 18 years. Health workforce in rural areas has been feminizing faster than urban areas. Marginalized professions like doctors in public health and traditional Chinese medicine have been feminizing at a faster speed than the prominent professions in clinical medicine. Gender equity， especially on pay gaps, should be considered in policies over the career course for health workforce to foster a more supportive environment to improve gender diversity.