bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change and stock market: a review
Authors: Tay Bee-Hoong 
Published: March 2023

Abstract
Climate change-related events are having a growing impact on the economy and financial markets. However, it is still difficult to quantify how climate change affects the financial system. The purpose of this research is to provide an overview of the relationship between climate risk factors and the stock market. The review focuses on the regions and methodologies used based on the selected publications for the past five years. The results revealed that most studies focused on developed economies, like those in the US and Europe, and adopted time series and panel regression in the analysis. The findings imply that future studies may focus on a wider range of issues, including developing countries and more advanced techniques in the analysis. The study also showed that, based on the evidence currently available, little is known about how investors assess climate threats; hence, a future study may close this knowledge gap. However, since this research reviewed the selected studies for the last five years, it has several limitations. A comprehensive investigation is needed, especially regarding the potential impacts of the pandemic on the environment and how it could spread to the stock market.
Geochemical assesment of heavy metals in postmining laterite nickel, North Konawe Southeast Sulawesi
Authors: Mustafa M , Maulana A , Irfan U R , Tonggiroh A 
Published: March 2023

Abstract
This study aims to determine the concentration and migration of various heavy metals in soil texture. A total of 21 soil samples from Block A (12 samples) and Block B (9 samples), were inductively combined with ICP-OES methodology to determine the concentration levels of Mn,Cr,Ni,Fe,Zn and ICP-MS for Co,Pb,Cd in soil samples as toxic contaminants. The results showed I-geo indicated contamination levels that ranged from practically uncontaminated for Cd, uncontaminated to moderately for Pb, uncontaminated to moderately contaminated soil for Fe, moderately contaminated for Co,Zn,moderately to heavily contaminated For Mn,Ni , heavily contaminated for Cr. I-geo relationship and heavy metal concentration. Although Block A and Block Igeo have the same category, which is of concern are Cd and Pb, the concentrations of these two heavy metals are very small. Generally, Cd and Pb react chemically under acidic conditions, whereas lateritic soil is an alkaline oxide soil. Heavy metals Cr and Mn function freely to control the mobility of Fe, Co, Ni. And Fe only controls Co and Ni. While Pb, Zn Cd are included in the low mobility group or zero contamination. Multidimensional scaling statistics (MDS) for two-dimensional mapping in blocks A Mn, Co, Ni, Cr shows active mobility following the soil depth where the chemical function of Fe controls the mobility of Mn so that the concentration of Mn increases, three-dimensional mapping shows that Cr and Fe function to control the mobility of Co, Mn,Ni so that the concentration increases. Two-dimensional mapping in Block B, Cr and Mn functions freely to control the mobility of Fe, Co, Ni. And Fe only controls Co and Ni. While Pb, Zn Cd are included in the low mobility group or zero contamination, three-dimensional mapping is known to have active concentrations of Cr and Mn and control the mobility of Ni, Co, Fe.
The development of quadcopter using Arducopter APM 2.8 with autopilot for tracking point of drop-off goods
Authors: Suparta W , Basuki A , Arsyad M 
Published: March 2023

Abstract
This research reported the development of a drone withinside the shape of a quadrotor to track positions over a certain geographic area on autopilot. The system includes an Ardupilot Mega (APM) 2.8 flight controller, Ublox NEO M8N GPS module with compass, Racerstar 920kV 2-4S Brushless Motor, Flysky Receiver FS-iA6B with FS-i6 Remote Control Transmitter, DJI F450 quadcopter frame kits with touchdown tools skid, and a LiPo Battery 3300 mAh 35C. The ground control system is set up and run through an open-source software so-known as Mission Planner. The tracking system is evolved as a payload together with BME280 sensors controlled through Arduino Uno R3 SMD. Google Maps from Mission Planner are set via waypoints. The readings from the BME280 barometer sensor are used to examine the right coordinates on the waypoint. This correction may be very crucial while a drone is implemented to a delivery system. The results show that the average error at every waypoint is 5%, which shows that one waypoint can be used as a drop-off point factor for goods to customers.
Statistical analysis of stone mastic asphalt containing steel fiber
Authors: Shaffie E , Shiong F , Ismail N N , Ahmad J , Arshad A K , Ismail M Y 
Published: March 2023

Abstract
The use of various fibers in asphalt mixes has been developed and applied to enhance pavement performance. The conventional asphalt mixture can be improved by including steel fibre as an additive in the asphalt mixture. However, the use of steel fibre in SMA mixtures was not widely studied. Consequently, the objective of this study was to evaluate the effect of steel fibre on the volumetric properties and characterize the performance of steel fibre in SMA mixture. Different steel fiber proportions of 0%, 0.3%, 0.5%, and 0.7% by the total weight of the mixture were used in this study. The test conducted includes the Marshall stability and Flow test, and the Resilient Modulus Test. Response Surface Methodology (RSM) from Design Expert Software was then performed to determine the most optimum properties from the experimental data. The test results revealed that adding steel fiber greatly improved the SMA mixture’s resistance to deformation while also increasing its stability, reducing the abrasion loss, and increasing the stiffness of the SMA mixture. Optimized performance was observed at 0.3% steel fiber content and 1598 MPa of resilient modulus. The relative error results show acceptable agreement between the prediction and the experiment which is considered tolerable and acceptable. This demonstrates that the software optimization of the specific SMA with steel fiber characteristics by the RSM technique has the desired precision for laboratory tests.
Structural, particle size distribution, and electrochemical behavior of double perovskite oxide doped Ce0.8Sm0.2O1.9 for intermediate temperature solid oxide fuel cells
Authors: Subardi A , Fu Y P 
Published: March 2023

Abstract
Double perovskite SmBa0.5Sr0.5Co2O5+δ(70%)+Ce0.8Sm0.2O1.9(30%) as SBSC70+SDC30 cathode was fabricated using solid-state reaction technique and investigated as cathode material for solid oxide fuel cells operating at intermediate temperature (IT-SOFC). This work aims to determine the effect of SDC electrolyte doping into double perovskite cathodes on SOFC performance. LS-POP carried out particle size distribution analysis, and the equipment operates on a light source (HE-Ne laser) basis. XRD was used to determine the structure of the cathode powder, and SEM was used to analyze the microstructure morphology. Symmetrical cells were tested using a potentiostat Voltalab PGZ 301. The distribution of particle size for the SBSC70+SDC30 cathode was in the range of 1.41-2.03 µm. The polarization resistance (Rp) value of SBSC70+SDC30 cathode decreases with increasing temperature from 1.22 cm2 at 600°C to 0.21 cm2 at 800°C. The SBSC70+SDC30 activation energy (Ea) for Rp was 117. 3 kJ mol−1. From the overall results, double perovskite SBSC70+SDC30 cathode has potential as a cathode of medium temperature SOFC cells.
Nitrogen sources affect the growth of local strain Euglena sp. isolated from Dieng Peatland, Central Java, Indonesia, and their potential as bio-avtur
Authors: Erfianti T , Maghfiroh K Q , Amelia R , Kurnianto D , Sadewo B R , Marno S , Devi I , Dewayanto N , Budiman A , Suyono E A 
Published: March 2023

Abstract

Euglena sp. is a member of the Euglena genus that has been successfully isolated under extreme conditions. The pH level of Dieng Peatland is 2.0-3.5. that suitable for the growth of Euglena. There are several ways to increase biofuel production in Euglena sp. by increasing the production of lipids and fatty acids produced through cultivation engineering, metabolic engineering and genetic engineering. One of the efforts in increasing growth, biomass and lipid levels in microalgae, especially Euglena sp. is to provide nitrogen variation in his cultivation medium. The concentration of nitrogen applied to the culture medium is able to increase growth, biomass production and total lipids in microalgae. The aim of this article was to analyze the effect of nitrogen sources in form of Sodium Nitrate (NaNO3) on the growth of microalgae and biomass production. The results showed that NaNO3 stimulated Euglena sp. to produce the highest amount of biomass (0,377 gram/L) after adding 1,5 grams of NaNO3.
The Thermal Manifestation Monitoring Program at Muara Labuh Case Studies
Authors: Sihotang Mauliate , Azis Herwin , Ganefianto Novi , Azka Ghilman , Aulia Nurul , Nugroho Indra A. , Suryantini  , Wibowo Hendro 
Published: March 2023

Abstract
The thermal manifestations at the Muara Labuh field are monitored regularly to see their behaviors in response to the field production. The monitoring results are then used to identify and mitigate any potential hazards associated with the thermal area changes. This paper presents the monitoring results on the main thermal features Idung Mancung (IM) fumaroles complex, located in the vicinity of the steam cap production zone in the Northeast (NE) Sector of the field. Due to its proximity to the main production area, this thermal complex is considered to be susceptible to any reservoir changes. The thermal manifestations characteristics monitored are areal extent, numbers of the thermal funnels, the activities, physical and chemical characteristics, and geophysical signatures. Baseline data were taken from previous remote sensing studies, geology maps, and thermal manifestation geochemistry surveys prior to production periods. Remote sensing studies using true color composite (TCC) and NDVI suggest that the IM fumarole area covers the wider area prior to stage-1 project development in 2017. After production, periodic aerial photo analysis suggests no changes in IM fumarole thermal area growth. The fact is supported by the periodic Thermal Infra-Red Image (TIR), which shows no sign of thermal anomaly still contained inside the IM fumarole baseline area. IM fumarole field checks show that lack of thermal area changes and no sign that the manifestations have become more aggressive. Temperature and flow rate observation on several manifestation funnels indicates that rainfall rate variation affects the manifestation activities and temperature. As for the fumarole gas chemistry, the IM main fumarole shows a decreasing trend in NCG and CO2 contents from 2016 to 2021 and increasing in H2S, which indicates the return of degassing fluid. After one year of field operation, the microgravity and leveling survey in the IM fumarole area show slight changes from -0.1 to -0.14 mGal. The changes correspond with the area subsidence rate of -10 to -15 mm/yr. These changes are still considered low compared to other operating geothermal fields and did not directly affect the thermal manifestation activity.
Hululais Field Review from Geoscientific Exploration to Exploitation Stage
Authors: Dwikorianto Tavip , Daud Yunus , Martha Agustya Adi , Mulyanto  
Published: March 2023

Abstract
Geothermal studies in Hululais carried out by Pertamina was started in 1993 with an exploration survey. The detailed geological mapping as the earliest geothermal resource assessment of Hululais was done internally by Pertamina. The geochemical study was done together with the geological study. The geophysical study was carried out using three methods. The gravity survey was run in 1993 for 320 points along 12 trace lines, while the magnetotelluric survey was conducted in 2006 and 2012 for 64 locations with 1-2 km spacing. The microearthquake survey was done in 2012 for 115 days monitoring time by six sensors in 10 km spacing and in 2019. The conceptual model as a product of the integrated study of three geoscientific surveys shows that the upflow zone is interpreted in Suban Agung – Suban Gregok in the southern area. Fumarole, mud pool and steam-heated hot spring are found in this zone. The outflow zone is interpreted towards the north in Semelako area supported by the chloride hot spring. The appearance of these manifestations is possibly controlled by fault structure in Musi Segment zone of Sumatra Fault Zone (SFZ). The heat source comes from granodiorite intrusion below Bukit Beriti Besar – Bukit Gedang Hululais. The cap rock has 500 meters thick in the upflow zone and increases to 800 meters thick towards the outflow zone in the northern part of the study area. The upflow zone was proved by two exploration wells that drilled until 3000 mMD. The first well in Suban Agung has a high temperature reach 300°C with neutral reservoir fluids and good fault structure permeability. The second exploration well that drilled towards outflow zone shows a temperature of 205°C with neutral reservoir fluids but with low permeability. In the exploitation stage, 21 development wells have been drilled for making the update conceptual model. Among them, ten wells are production wells and the remains are reinjection ones. The permeability in the reinjection wells is not so good compared to the production wells. It might be due to secondary mineral filling in the fault structure permeability zone, so this situation causes a problem in injection water to the reservoir. Investigation of the subsurface permeability distribution in the Hululais reservoir is challenging, so further research should be done to answer this challenge.
Preliminary Estimation of Geological Structure Based on Relocated Hypocenter of Microearthquake: Case Study at “X” Geothermal Field
Authors: Hermawan Irfan Berrizki , Rachmat Mohammad , Afnimar  , Pratama Angga Bakti , Lawrens Fernando , Prabowo Billy Sugiartono , Delliansyah Rendy , Ryannugroho Riskiray , Hakim Firdaus Al , Widyoyudo Wiku , Iskandar Chevy , Fajri Reza Jamil 
Published: March 2023

Abstract
Generally, analysis of geological structure in the geothermal field is carried out using remote sensing methods, geological mapping, and gravity analysis. These methods can provide the distribution of geological structure on the surface but cannot provide information on whether the structure is active or not. This study aims to utilize improved hypocenter location which can be used to delineate the distribution of active faults. This is useful for obtain a better interpretation of geological structures in geothermal areas. Hypocenter locations are determined by picking the arrival time of the P-wave and S-wave. This method sometimes leads to uncertainty of hypocenter location due to subjectivity of picking arrival time. The double-difference method is applied with additional input pairing events from waveform cross-correlation (WCC) to overcome the uncertainty of hypocenter location. The result shows 3 microearthquake clusters formed in the western, central, and eastern parts of the “X” Geothermal Field. The cluster formed in the western area shows that there are two orientations of conjugated hypocenter distribution with the orientation of NW-SE and NE-SW. These hypocenters reveal the presence of geological structures which provide permeability pathways for fluids rising in the western part of the geothermal field. Multiplet-clustering analysis in the middle cluster which coincides with the reservoir zone shows two different sub-clusters indicating the possibility of two different sources mechanism working in the area. By integrating all the analysis and hypocenter distribution, these methods provide a better interpretation of structure’s distribution in the “X” Geothermal Field.
Sensory Integration Deficits in Neurodegenerative Diseases: Implications for Apraxia
Authors: Baumard Josselin , Lesourd Mathieu , Remigereau Chrystelle , Jarry Christophe , Lebaz Samuel , Etcharry-Bouyx Frédérique , Chauviré Valérie , Osiurak François , Le Gall Didier 
Published: March 2023

Abstract

Objective
Apraxia is the inability to perform voluntary, skilled movements following brain lesions, in the absence of sensory integration deficits. Yet, patients with neurodegenerative diseases (ND) may have sensory integration deficits, so we tested the associations and dissociations between apraxia and sensory integration.

Methods
A total of 44 patients with ND and 20 healthy controls underwent extensive testing of sensory integration (i.e., localization of tactile, visual, and proprioceptive stimuli; agraphesthesia; astereognosis) and apraxia (i.e., finger dexterity, imitation, tool use).

Results
The results showed (i) that patients with Alzheimer’s disease, corticobasal syndrome, or posterior cortical atrophy were impaired on both dimensions; (ii) An association between both dimensions; (iii) that when sensory integration was controlled for, the frequency of apraxia decreased dramatically in some clinical subgroups.

Conclusion
In a non-negligible portion of patients, the hypothesis of a disruption of sensory integration can be more parsimonious than the hypothesis of apraxia in case of impaired skilled gestures. Clinicians and researchers are advised to integrate sensory integration measures along with their evaluation of apraxia.
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations
Authors: Ren Jian , Huang Yazi , Ren Yeqing , Tu Tianqi , Qiu Baoshan , Ai Daosheng , Bi Zhanying , Bai Xue , Li Fengzhi , Li Jun-Liszt , Chen Xing-jun , Feng Ziyan , Guo Zongpei , Lei Jianfeng , Tian An , Cui Ziwei , Lindner Volkhard , Adams Ralf H , Wang Yibo , Zhao Fei , Körbelin Jakob , Sun Wenzhi , Wang Yilong , Zhang Hongqi , Hong Tao , Ge Woo-ping 
Published: March 2023

Abstract
Cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations (SCCMs) are common vascular abnormalities of the CNS that can lead to seizure, haemorrhage and other neurological deficits. Approximately 85% of patients present with sporadic (versus congenital) CCMs. Somatic mutations in MAP3K3 and PIK3CA were recently reported in patients with sporadic CCM, yet it remains unknown whether MAP3K3 mutation is sufficient to induce CCMs. Here we analysed whole-exome sequencing data for patients with CCM and found that ∼40% of them have a single, specific MAP3K3 mutation [c.1323C&gt;G (p.Ile441Met)] but not any other known mutations in CCM-related genes.
We developed a mouse model of CCM with MAP3K3I441M uniquely expressed in the endothelium of the CNS. We detected pathological phenotypes similar to those found in patients with MAP3K3I441M. The combination of in vivo imaging and genetic labelling revealed that CCMs were initiated with endothelial expansion followed by disruption of the blood–brain barrier. Experiments with our MAP3K3I441M mouse model demonstrated that CCM can be alleviated by treatment with rapamycin, the mTOR inhibitor. CCM pathogenesis has usually been attributed to acquisition of two or three distinct genetic mutations involving the genes CCM1/2/3 and/or PIK3CA. However, our results demonstrate that a single genetic hit is sufficient to cause CCMs.
Nonsystematic Reporting Biases of the SARS-CoV-2 Variant Mu Could Impact Our Understanding of the Epidemiological Dynamics of Emerging Variants
Authors: Petrone Mary E , Lucas Carolina , Menasche Bridget , Breban Mallery I , Yildirim Inci , Campbell Melissa , Omer Saad B , Holmes Edward C , Ko Albert I , Grubaugh Nathan D , Iwasaki Akiko , Wilen Craig B , Vogels Chantal B F , Fauver Joseph R 
Published: March 2023

Abstract
Developing a timely and effective response to emerging SARS-CoV-2 variants of concern (VOCs) is of paramount public health importance. Global health surveillance does not rely on genomic data alone to identify concerning variants when they emerge. Instead, methods that utilize genomic data to estimate the epidemiological dynamics of emerging lineages have the potential to serve as an early warning system. However, these methods assume that genomic data are uniformly reported across circulating lineages. In this study, we analyze differences in reporting delays among SARS-CoV-2 VOCs as a plausible explanation for the timing of the global response to the former VOC Mu. Mu likely emerged in South America in mid-2020, where its circulation was largely confined. In this study, we demonstrate that Mu was designated as a VOC ∼1 year after it emerged and find that the reporting of genomic data for Mu differed significantly than that of other VOCs within countries, states, and individual laboratories. Our findings suggest that nonsystematic biases in the reporting of genomic data may have delayed the global response to Mu. Until they are resolved, the surveillance gaps that affected the global response to Mu could impede the rapid and accurate assessment of future emerging variants.
Definitive radiotherapy consisting of external beam radiotherapy without central shielding and 3D image-guided brachytherapy for patients with cervical cancer: feasibility for Japanese patients and dose–response analyses for local control in the low-dose range
Authors: Toita Takafumi , Wada Kentaro , Sutani Shinya , Umezawa Rei , Maemoto Hitoshi , Ii Noriko , Kawamura Tomoko , Ikushima Hitoshi , Takenaka Ryosuke , Konishi Koji , Yorozu Atsunori , Jingu Keiichi , Ariga Takuro , Nomoto Yoshihito , Yamashita Hideomi 
Published: March 2023

Abstract

Objective
To assess the feasibility of external beam radiotherapy without central shielding in definitive radiotherapy for Japanese patients with cervical cancer.

Methods
We retrospectively analysed the data of cervical cancer patients treated with definitive radiotherapy consisting of external beam radiotherapy without central shielding and three-dimensional-image-guided brachytherapy.

Results
The study included 167 patients (T1 + 2 = 108, T3 + 4 = 59) from eight Japanese institutions. For three-dimensional-image-guided brachytherapy, intra-cavitary and interstitial brachytherapy was utilized in 33 patients (20%). The median follow-up was 26.6 months (interquartile range, 20–43.2). The maximum rectal D2 (75 Gy)/bladder D2 (90 Gy) constraints were deviated by 6%/10% and 10%/5% for T1 + 2 and T3 + 4, respectively. The 2-year incidence of ≥grade 3 proctitis/cystitis was 4%/1% for T1 + 2 and 10%/2% for T3 + 4. The 2-year local progression-free survival was 89% for T1 + 2 and 82% for T3 + 4. For T1 + 2, the 2-year local progression-free survival for the high-risk clinical target volume D90 ≥ 68 Gy (indicated by receiver operating characteristic analysis; area under the curve = 0.711) was 92% versus 67% for &lt;68 Gy (log-rank; P = 0.019). Cox multivariate analysis indicated that the high-risk clinical target volume D90 was one of independent predictors of local failure (P = 0.0006). For T3 + 4, the 2-year local progression-free survival was 87% for the high-risk clinical target volume &lt;82 cm3 (area under the curve = 0.67) and 43% for ≥82 cm3 (P = 0.0004). Only the high-risk clinical target volume was an independent predictor of local failure (P = 0.0024).

Conclusions
Definitive radiotherapy consisting of external beam radiotherapy without central shielding and three-dimensional-image-guided brachytherapy was feasible for Japanese patients with cervical cancer. Dose de-escalation from the current global standards is suggested for patients with T1 + 2 disease.