bluuebunny/crossref_metadata_2025_split huggingface dataset:
Have Industrial Robots Improved Pollution Reduction? A Theoretical Approach and Empirical Analysis
Authors: Zhu Huzhou , Sang Bin , Zhang Chunyuan , Guo Lin 
Published: July 2023

AbstractTo investigate whether industrial robots have improved the ecological environment, this study integrated the adoption of robot technology and pollution abatement into Melitz's heterogeneous firm model. This showed that using robots in production can lower firms' pollution intensity by increasing their abatement investments, and this reduction effect is greater for higher polluting firms and those subject to weaker local environmental regulations. These theoretical expectations were then confirmed through a series of empirical investigations based on Bartik instrument regressions, with multiple robustness checks as well as heterogeneity and mechanism analyses. This paper adds to the literature on the relationships between automation technologies and green transformation. It shows that in the pursuit of economic growth and environmental protection, it is necessary for policymakers to shift from pollution control to technical support for traditional manufacturing firms.
Parental attachment and childhood trauma in adolescents engaged in non‐suicidal self‐injury
Authors: Bahali Kayhan , Durcan Gizem , Topal Melike , Önal Bedia Sultan , Bilgiç Ayhan , Tanıdır Canan , Aytemiz Tuğçe , Yazgan Yankı 
Published: July 2023

AbstractAimIn this study, it was aimed to compare parental attachment and childhood traumas in adolescents with NSSI with healthy peers.MethodsFifty adolescents aged 14–18 years with lifetime NSSI and 56 healthy peers were included in the study. Inventory of Statements About Self‐injury (ISAS), The Parental Bonding Instrument (PBI) and Child Trauma Questionnaire (CTQ‐28) scales were used.ResultsEighty‐two percentage of the NSSI group and 70% of the control group were girls. The mean age was 15.6 ± 1.1 years in the NSSI group and 15.3 ± 0.9 years in the control group. There was no significant difference between the groups in terms of age and gender. The NSSI group had more negative scores than the control group in terms of childhood traumas and attachment characteristics to both mother and father. The analyses showed that mother PBI care/control and sexual abuse score had a relationship with both ISAS Autonomic Functions and ISAS Social Functions scores.ConclusionsThese results suggest that secure attachment with the mother may be protective for both the autonomic and social functions of the NSSI. Therefore, interventions for dysfunctional parental attachment may prevent the development of NSSI.
Increasing challenges to trial recruitment and conduct over time
Authors: Kerr Wesley T. , Reddy Advith S. , Seo Sung Hyun , Kok Neo , Stacey William C. , Stern John M. , Pennell Page B. , French Jacqueline A. 
Published: July 2023

AbstractObjectiveThis study was undertaken to evaluate how the challenges in the recruitment and retention of participants in clinical trials for focal onset epilepsy have changed over time.MethodsIn this systematic analysis of randomized clinical trials of adjunct antiseizure medications for medication‐resistant focal onset epilepsy, we evaluated how the numbers of participants, sites, and countries have changed since the first such trial in 1990. We also evaluated the proportion of participants who completed each trial phase and their reasons for early trial exit. We analyzed these trends using mixed effects generalized linear models accounting for the influence of the number of trial sites and trial‐specific variability.ResultsThe number of participants per site has steadily decreased over decades, with recent trials recruiting fewer than five participants per site (reduction by .16 participants/site/year, p < .0001). Fewer participants also progressed from recruitment to randomization over time (odds ratio = .94/year, p = .014). Concurrently, there has been an increase in the placebo response over time (increase in median percent reduction of .4%/year, p = .02; odds ratio of increase in 50% responder rate of 1.03/year, p = .02), which was not directly associated with the number of sites per trial (p > .20).SignificanceThis historical analysis highlights the increasing challenges with participant recruitment and retention, as well as increasing placebo response. It serves as a call to action to change clinical trial design to address these challenges.
Colic due to dorsally located perirectal abscesses: A retrospective case series of six horses
Authors: Weber Lisa Annabel , Verhaar Nicole , Feige Karsten 
Published: July 2023

SummaryPerirectal abscesses have only rarely been reported in horses. This case series describes the clinical signs, diagnosis, treatment and outcome of six horses with this condition. The equids affected were geldings or stallions of various breeds and aged from 4 months to 21 years (median age 10 months). Typical clinical signs included colic with tachycardia, tenesmus, dyschezia and abdominal distension. The diagnosis was obtained by transrectal palpation and ultrasonographic examination in five of six horses and by median laparotomy in one horse. All abscesses were located dorsally to the rectum. Rectal impaction and large colon tympany were common secondary findings. Microbiologic examination of abscess content revealedStreptococcus equisubspecieszooepidemicusin all horses. Abscesses were treated by a combination of medical and surgical approaches. One horse had to be euthanised due to complete obstruction of the pelvis by the abscess. In the other horses (5/6), the disorder was associated with an excellent prognosis. In terms of the total population of horses presenting with colic in the investigated period, the prevalence of cases with perirectal abscesses was 0.4%. Although uncommon, described cases indicate that perirectal abscesses should be considered as differential diagnosis for young and mature horses with colic signs.
Intelligent path planning algorithm of Autonomous Underwater Vehicle based on vision under ocean current
Authors: Wang Yibo , Xi Meng , Weng Yubo 
Published: July 2023

AbstractAutonomous Underwater Vehicle (AUV) is an important tool for intelligent ocean applications, which can be applied to detect underwater environment and search target. Path planning is the key technology to realize AUV intelligence, which has important research significance. Aiming at the dynamic path planning problem, the Regional Ocean Modeling System (ROMS) was first applied to the AUV three‐dimensional (3D) dynamic path planning, and a Gate Recurrent Unit Proximal Policy Optimization with Local Vision (GPPO‐LV) model based on local vision is proposed. The 3D ocean current environment is constructed based on the ROMS simulation data. The local vision matrix is constructed based on underwater images, and the features of local vision are extracted using convolutional neural network. Furthermore, Gate Recurrent Unit (GRU) network is used to mine the hidden information between observation states. Finally, the Actor network for strategy output and the Critical network for action value evaluation are constructed, and strategies are optimized in the process of interaction with the environment. The experiment shows that under various unknown environments, AUV can carry out real‐time path planning under real ocean current data, and has good obstacle avoidance ability.
A marine protected area network does not confer community structure resilience to a marine heatwave across coastal ecosystems
Authors: Smith Joshua G. , Free Christopher M. , Lopazanski Cori , Brun Julien , Anderson Clarissa R. , Carr Mark H. , Claudet Joachim , Dugan Jenifer E. , Eurich Jacob G. , Francis Tessa B. , Hamilton Scott L. , Mouillot David , Raimondi Peter T. , Starr Richard M. , Ziegler Shelby L. , Nickols Kerry J. , Caselle Jennifer E. 
Published: July 2023

AbstractMarine protected areas (MPAs) have gained attention as a conservation tool for enhancing ecosystem resilience to climate change. However, empirical evidence explicitly linking MPAs to enhanced ecological resilience is limited and mixed. To better understand whether MPAs can buffer climate impacts, we tested the resistance and recovery of marine communities to the 2014–2016 Northeast Pacific heatwave in the largest scientifically designed MPA network in the world off the coast of California, United States. The network consists of 124 MPAs (48 no‐take state marine reserves, and 76 partial‐take or special regulation conservation areas) implemented at different times, with full implementation completed in 2012. We compared fish, benthic invertebrate, and macroalgal community structure inside and outside of 13 no‐take MPAs across rocky intertidal, kelp forest, shallow reef, and deep reef nearshore habitats in California's Central Coast region from 2007 to 2020. We also explored whether MPA features, including age, size, depth, proportion rock, historic fishing pressure, habitat diversity and richness, connectivity, and fish biomass response ratios (proxy for ecological performance), conferred climate resilience for kelp forest and rocky intertidal habitats spanning 28 MPAs across the full network. Ecological communities dramatically shifted due to the marine heatwave across all four nearshore habitats, and MPAs did not facilitate habitat‐wide resistance or recovery. Only in protected rocky intertidal habitats did community structure significantly resist marine heatwave impacts. Community shifts were associated with a pronounced decline in the relative proportion of cold water species and an increase in warm water species. MPA features did not explain resistance or recovery to the marine heatwave. Collectively, our findings suggest that MPAs have limited ability to mitigate the impacts of marine heatwaves on community structure. Given that mechanisms of resilience to climate perturbations are complex, there is a clear need to expand assessments of ecosystem‐wide consequences resulting from acute climate‐driven perturbations, and the potential role of regulatory protection in mitigating community structure changes.
Risk factors for stress urinary incontinence recurrence after midurethral sling revision
Authors: Six Jeanne‐Claire , Pinsard Marion , Guerin Sonia , Gasmi Anis , Coiffic Jerry , Richard Claire , Haudebert Camille , Nyangoh Timoh Krystel , Hascoet Juliette , Peyronnet Benoit 
Published: July 2023

ObjectivesThe purpose of this study was to report the rate of stress urinary incontinence (SUI) recurrence after sling revision, and to determine predictive factors of SUI recurrence.MethodsWe conducted a retrospective cohort study in a single academic center between 2005 and 2022, of patients who underwent sling revision. Four surgical techniques were used for sling revision (loosening, section, partial, and total excision). The primary endpoint was recurrence of SUI at 3 months postoperatively, and the other outcome of interest was the rate of subsequent anti‐incontinence surgical procedure.ResultsSixty‐nine patients were included for analysis. SUI recurred in 46.4% of patients. Fifteen patients underwent a subsequent anti‐incontinence procedure (21.8%). The time to revision was significantly longer in the group with recurrent SUI (median: 84.5 vs. 44.8 months; p = 0.004). The recurrence rate differed significantly depending on the revision technique: 7.7% after sling loosening, 22.2% after sling section, 60% after partial excision, and 66.7% after complete sling removal (p = 0.001). The risk of SUI recurrence was lower for those whose indication of reoperation was voiding dysfunction (27.3% vs. 66.7%; p = 0.002), and was higher for those who underwent a trans‐obturator tap rather than a tension‐free vaginal tape revision (68.4% vs. 35.7%; p = 0.02). In multivariate analysis, only the revision technique remained significantly associated with the risk of recurrence of SUI (complete excision vs. section: odds ratio = 4.66; p = 0.04).ConclusionThe risk of SUI recurrence may differ widely according to the techniques used, and it seems that the less extensive the surgical procedure is, the lower the risk is.
Selling exclusively or widely? Optimal strategic responses under online platform power asymmetry and competition
Authors: K. Li Kunpeng , Y. Li Yang , Gharehgozli Amir 
Published: July 2023

AbstractWe study an e‐commerce marketplace consisting of a third‐party seller, a dominant platform, and a competing platform. The seller pays referral fees to sell on the platforms. The dominant platform has a larger consumer base and offers an exclusive program. We formulate a game theoretic model to study strategic responses for all parties involved. The research questions are: How would the seller optimally choose between the two selling options: “go exclusive” with the dominant platform or “go wide” with both the dominant and the competing platforms? How would the dominant platform optimally adjust the referral fee in the exclusive program? How would the competing platform optimally discount the referral fee to compete with the dominant platform? We find that it is optimal for the seller to sell exclusively on the dominant platform if the referral fee adjustment in the exclusive program is lower than a threshold value. For the dominant platform, we identify the optimal value of the referral fee adjustment so that the seller can be enticed to choose the selling strategy that benefits the dominant platform as well. For the competing platform, we prove that there exists an optimal value of the referral fee discount. We also identify the market conditions that it is optimal for the competing platform to discount the referral fee or to set the referral fee the same as the dominant platform. We contribute to the e‐commerce literature by studying exclusive selling and platform competition while incorporating base demand asymmetry and referral fee asymmetry.
The effects of different regenerative technologies and materials on wound healing after surgical endodontic therapy: A meta‐analysis
Authors: Wang Ge , Yuan Fang , Ying Wanggui , Xu Jie 
Published: July 2023

AbstractA meta‐analysis was performed to assess the effects of different regenerative technologies and materials on wound healing after surgical endodontic therapy and provide a reference for surgical endodontic treatment. We searched for studies on the use of regenerative technologies and materials in surgical endodontic therapy via PubMed, MEDLINE, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Data from the time of database creation to December 2022. Two researchers independently screened the literature, extracted information based on the inclusion and exclusion criteria, and evaluated the quality of the included studies. A meta‐analysis was performed using Review Manager 5.4. The results showed that the use of regenerative technologies and materials significantly reduced wound healing failures (risk ratio [RR]: 0.30, 95% confidence intervals [CI]: 0.22–0.40, p < 0.001). Moreover, autologous platelet concentrations (APCs) (RR: 0.28, 95% CI: 0.15–0.53, p < 0.001) and collagen membrane plus bovine‐derived hydroxyapatite (RR: 0.27, 95% CI. 0.12–0.61, p = 0.002) were more effective in improving wound healing failure rates than collagen membrane alone (RR: 0.51, 95% CI: 0.20–1.25, p = 0.140). Our findings showed that APCs, as well as collagen membrane plus bovine‐derived hydroxyapatite, significantly improved wound healing after surgical endodontic therapy. In contrast, collagen membrane alone did not significantly improve wound healing outcomes. However, currently available studies vary significantly in sample size and methodologies. Hence, high‐quality randomised controlled studies with large sample sizes are necessary to validate our findings.
Preclinical study of diabetic foot ulcers: From pathogenesis to vivo/vitro models and clinical therapeutic transformation
Authors: Du Yuqing , Wang Jie , Fan Weijing , Huang Renyan , Wang Hongfei , Liu Guobin 
Published: July 2023

AbstractDiabetic foot ulcer (DFU), a common intractable chronic complication of diabetes mellitus (DM), has a prevalence of up to 25%, with more than 17% of the affected patients at risk of amputation or even death. Vascular risk factors, including vascular stenosis or occlusion, dyslipidemia, impaired neurosensory and motor function, and skin infection caused by trauma, all increase the risk of DFU in patients with diabetes. Therefore, diabetic foot is not a single pathogenesis. Preclinical studies have contributed greatly to the pathogenesis determination and efficacy evaluation of DFU. Many therapeutic tools are currently being investigated using DFU animal models for effective clinical translation. However, preclinical animal models that completely mimic the pathogenesis of DFU remain unexplored. Therefore, in this review, the preparation methods and evaluation criteria of DFU animal models with three major pathological mechanisms: neuropathy, angiopathy and DFU infection were discussed in detail. And the advantages and disadvantages of various DFU animal models for clinical sign simulation. Furthermore, the current status of vitro models of DFU and some preclinical studies have been transformed into clinical treatment programs, such as medical dressings, growth factor therapy, 3D bioprinting and pre‐vascularization, Traditional Chinese Medicine treatment. However, because of the complexity of the pathological mechanism of DFU, the clinical transformation of DFU model still faces many challenges. We need to further optimize the existing preclinical studies of DFU to provide an effective animal platform for the future study of pathophysiology and clinical treatment of DFU.
Information influenced consumers' attitudes toward A2 milk: An approach using text highlighting technique
Authors: Nogueira Ana Carolina Ratti , Amorim Katiúcia Alves , Bastos Sabrina Carvalho , Pinheiro Ana Carla Marques , Teixeira Rafael Bastos , da Cruz Adriano Gomes , Rodrigues Jéssica Ferreira 
Published: July 2023

AbstractDairy products are constantly launched, mainly focusing on healthiness, especially for the public, like people with food allergies. However, raising consumer awareness is a great challenge, especially about new products with health claims. This study used the text‐highlighting (TH) methodology associated with acceptance tests to assess Brazilian consumers' explicit attitudes toward A2 milk. In the task, consumers were asked to highlight in a text the terms they “liked” or “disliked” about the milk's nutritional importance, the difference between A1 and A2 milk, health benefits and harmful effects, and the necessity for more studies and awareness about the A2 milk. Sensory acceptance pre and post‐text were also measured. A high engagement of consumers with the TH could be observed, which suggests good intuitiveness of the technique. Including information about the nutritional value of milk and the difference between both kinds of milk may increase positive consumer perception, as it encourages consumers to express their value judgment in the form of “liked”. On the other hand, information simultaneously, the harms of the formation of BCM‐7 (in A1 milk) prompted consumers to express their value judgment in the “disliked” highlights. This underscores the importance of raising consumer awareness about the product and the need for more studies on the real effects of A2 milk on the body and the implementation of specific legislation. Moreover, it was observed that information should be in a simple and direct language, as technical terminology in the text did not have a positive effect, such as the information about the genetic mutation. TH produced valuable insights that can be used in communication strategies with A2 milk.Practical applicationThe findings of this study show practical utility for consumer‐based methodologies, focusing on the text‐highlighting method approach and its influence on consumer perceptions. Moreover, the results show practical utility to direct regulation, consumer awareness, and product commercialization of A2 milk.
Accuracy and applicability of periodontitis risk assessment tools: A critical appraisal
Authors: Farina Roberto , Lopez Rodrigo , Simonelli Anna , Trombelli Leonardo 
Published: July 2023

AbstractCurrently, periodontal risk assessment finds application at first visit (to identify individuals at high risk of either disease incidence, if still healthy, or disease progression, if already diseased) as well as at patient monitoring after active treatment and enrolment in a supportive periodontal care program. Although the current case definition of periodontitis embeds a prognostic determination (ie, periodontitis grade) that showed a predictive value for periodontitis‐related tooth loss, some limitations of periodontitis grade call for the implementation of different risk assessment tools in clinical practice. For some of these, significantly higher accuracy in predicting tooth loss during supportive periodontal care was reported compared with periodontitis grade. Validated periodontal risk assessment tools may be functional to obtain greater adherence to the suggested preventive and treatment protocols, improve oral hygiene performance, and tailor supportive periodontal care. Interestingly, periodontal risk can also be informative of the risk of peri‐implantitis in patients programmed for implant placement or rehabilitated with dental implants. A critical appraisal on the rationale behind risk assessment and the balance between the advantages and limitations of exercising risk assessment in periodontology is presented.
Research progress on the neutrophil components and their interactions with immune cells in the development of psoriasis
Authors: Wang Zhenhui , Shi Dongmei 
Published: July 2023

AbstractBackgroundPsoriasis is an immune‐mediated chronic inflammatory disease, and currently it is widely believed that the IL‐23/IL‐17 axis and Th17 cells play a critical and central role. However, increasing evidence suggests that neutrophils may interact with a variety of immune cells to play an indispensable role in psoriasis.Materials and methodsWe searched the recent literature on psoriasis and neutrophils through databases such as PubMed and CNKI, and summarized the findings to draw conclusions.ResultsNeutrophils can promote the development of psoriasis by secreting IL‐23, IL‐17, and cytokines with TH17 cell chemotaxis. Activated keratinocytes (KCs) can attract and activate neutrophils, induce the formation of neutrophil extracellular traps (NETs). KCs can also expose self‐antigens which lead to strong autoimmune reactions. The granule proteins secreted by activated neutrophils can activate IL‐36, which converts vulgaris psoriasis to generalized pustular psoriasis (GPP).ConclusionThe function of neutrophils components and the interaction between neutrophils and immune cells play an essential role in the pathogenesis of psoriasis. The aim is to provide a theoretical basis for the exploration of targeted clinical treatments and fundamental research on the pathogenesis of psoriasis.