bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient-Centered Core Impacts Sets (PC-CIS): What They Are and What They Are Not
Authors: Perfetto Eleanor M. , Schrandt Suz , Escontrías Omar A. , Burke Laurie B. 
Published: February 2023

Letter to the Editor
We are writing regarding the Innovations in Pharmacy commentary entitled, “Evidentiary Standards for Patient-Centered Core Impact Value Claims.”(1) We thank Dr. Langley for commenting on the National Health Council’s work on patient-centered core impact sets (PC-CIS), an initiative spearheaded by the nonprofit organization and its membership with multi-stakeholder representation and input.(2-4) While we have tried to be clear and transparent about the intent of PC-CIS, the commentary made it apparent to us we need to (and will) do more to be explicit about what a PC-CIS is and is not, and its possible downstream uses.
We believe the PC-CIS concept was misrepresented in the commentary and want to provide clarification for readers so they can consider the merits of the initiative for themselves.
Spring: A Season Of New Beginnings And The End Of The Dinosaurs
Authors: During Melanie 
Published: February 2023

We probably all know about the extinction of the dinosaurs 66 million years ago, from an asteroid hitting the Yucatán peninsula. The impact caused tsunamis and earthquakes. Pieces of molten Earth rock were ejected into space, and later rained back down. This event caused death for everything exposed. We describe how fishes from North Dakota help inform us on the season of the extinction.
Evaluation of antimicrobial property of nanochitosan coated orthodontic brackets against Streptococcus mutans and Lactobacillus acidophilus – an in vitro study
Authors: Mayma Nathasha , Sangeetha Duraisamy , Ravi Kannan 
Published: February 2023

Objectives:
The objectives of the study were to evaluate and compare the antimicrobial property of nanochitosan coated and uncoated stainless steel (SS) brackets against Streptococcus mutans and Lactobacillus acidophilus.

Materials and Methods:
22 SS orthodontic brackets coated with nanochitosan and 22 uncoated brackets were bonded to the crowns of extracted premolar teeth and prepared for the antimicrobial assay against S. mutans and L. acidophilus. The bacterial suspensions were incubated in Mueller Hinton broth and cultivated in Petri dish plates. The bacterial colonies were counted after 1, 6, 12, 24, and 72 h intervals using a digital colony counter. Inter and intragroup comparisons were done using independent sample t-test and repeated measures ANOVA (P ≤ 0.05).

Results:
The mean colony-forming units (CFU) of S. mutans and L. acidophilus showed a significant reduction in the coated brackets from 1 h to 72 h (P = 0.000). The mean CFU of S. mutans and L. acidophilus showed a significant increase in the uncoated brackets from 1 h to 24 h and decreased thereafter at 72 h (P = 0.000) except for S. mutans between 12 h and 72 h where the difference was not statistically significant (P = 0.837). The Mean CFU of S. mutans and L. acidophilus was significantly lesser in coated brackets compared to uncoated brackets at all-time intervals (P = 0.000).

Conclusion:
Nanochitosan coated orthodontic brackets showed significant antimicrobial properties against S. mutans and L. acidophilus in short-term up to 72 h compared to uncoated SS brackets.
Comparison of clinico-radiological profile, optical coherence tomography parameters, and outcome in MOGAD and Neuromyelitis optica spectrum disorder subtypes: A prospective observational study
Authors: Dhar Nikita , Kumar Mritunjai , Tiwari Ashutosh , Samanta Ramanuj , Bhadoria Ajeet Singh , Vivekanandhan S. , Saxena Sudhir , Kumar Niraj 
Published: February 2023

Objectives:The objectives of the study were to compare the clinico-radiological profile, optical coherence tomography (OCT) parameters and outcome in Myelin Oligodendrocyte Glycoprotein-IgG-associated disorders (MOGAD) and Neuromyelitis Optica Spectrum disorder subtypes.Materials and Methods:This prospective study involved collection of data regarding neurological assessment, neuroimaging, cerebrospinal fluid analysis, OCT parameters, treatment and outcome. Disease severity and disability were assessed using Expanded Disability Status Scale and modified Rankin scale. Patients were categorized into aquaporin-4 (AQP4+), MOGAD, and double negative (DN; both AQP4 and MOG negative).Results:Among 31 patients included, 42% were AQP4+, 32.2% were MOGAD, and 25.7% were DN. The median age at onset was comparable (AQP4+ vs. MOGAD vs. DN = 28 years vs. 24.4 years vs. 31.5years;P= 0.31). Females predominated in AQP4+ compared to MOGAD group (76.9% vs. 30%;P= 0.02). Majority of patients (73.5%) had a relapsing course with a median of two (range = 1–9) relapses. Ninety-nine demyelinating events occurred: Transverse myelitis (TM) in 60/99 (60.6%), optic neuritis (ON) in 43/99 (43.4%), area postrema (AP) syndrome in 20/99 (20.1%), and optico-spinal syndrome in 10/99 (10.1%). ON was common in MOGAD than AQP4+ patients (58.6% vs. 32.1%;P= 0.03). Spinal cord and brain lesions on magnetic resonance imaging (MRI) were seen in 90.3% and 54.8% patients, respectively. A significantly higher proportion of AQP4+ patients showed longitudinally extensive transverse myelitis as compared to MOGAD group (69.2 % vs. 20 %;P= 0.04), specifically involving dorsal cord (92.3% vs. 50%;P= 0.02). MRI brain lesions, especially involving AP, was frequent in DN than MOGAD (47.1% vs. 6.9%;P= 0.003) and AQP4+ (47.1% vs. 18.9%;P= 0.03) patients. AQP4+ group showed significant nasal RNFL thinning on OCT (P= 0.04). Although 6-month good functional outcome was better in MOGAD than DN and AQP4+ (80% vs. 71.4% vs. 41.7%) groups, they were comparable (P= 0.13).Conclusion:Nearly three-fourth of our patients showed a relapsing course, with TM being the most common clinical presentation. AQP4+ group showed female preponderance, frequent dorsal cord longitudinally extensive transverse myelitis, less frequent ON, and greater nasal RNFL thinning compared to MOGAD group. MRI brain lesions were more common in DN patients. All three groups exhibited good response to pulse corticosteroids and showed a comparable functional outcome at 6-month follow-up.
Flow diversion for indirect carotid-cavernous fistula: Still an off-label indication?
Authors: Brunasso Lara , Casamassima Nicola , Abrignani Sergio , Sturiale Carmelo Lucio , Incandela Francesca , Giammalva Giuseppe Roberto , Iacopino Domenico Gerardo , Maugeri Rosario , Craparo Giuseppe 
Published: February 2023

Background:Flow diversion (FD) is an established treatment for large or giant wide-necked unruptured intracranial aneurysms. In the past few years, the use of flow diverter devices was extended to several other “off-label” indications, including solitary or adjunctive treatment to coil embolization for direct (Barrow A type) carotid cavernous fistulas (CCFs). The use of liquid embolic agents still represents the first-line treatment for indirect CCFs. Typically, the ipsilateral inferior petrosal sinus or superior ophthalmic vein (SOV) is the preferred transvenous routes to access CCFs. In some cases, vessel tortuosity or different features make the endovascular access challenging, thus requiring different approaches and strategies. The aim of the study is to discuss rational and technical aspect in treating indirect CCFs referring to the most up-to-date literature. An alternative experience-based endovascular strategy with FD is described.Methods:We report the case of a 54-year-old woman diagnosed with indirect CCF and treated with flow diverter stent.Results:After multiple unsuccessful attempts at transarterial right SOV catheterization, a right indirect CCF fed by a single trunk at the ophthalmic origin from the internal carotid artery (ICA) was treated by ICA stand-alone FD. Blood flow was redirect and successfully reduced through the fistula, with immediately postprocedure improvement of the patient’s clinical status (ipsilateral proptosis and chemosis). Ten-months radiological follow-up showed the complete obliteration of the fistula. No adjunctive endovascular treatment was performed.Conclusion:FD appears a reasonable alternative stand-alone endovascular strategy also for selected difficult-to-access indirect CCFs, when all conventional routes are judged unfeasible. Further investigations will be necessary to better define and support this potential lesson-learned application.
Pengaruh Pembiayaan Murabahah Mudharabah Dan Musyarakah Terhadap Profitabilitas (ROA) Dengan Non Performing Financing (NPF) Sebagai Variabel Moderasi (Studi Pada Bank Muamalat Indonesia Periode 2012-2021)
Authors: Ramadhanti Fitria , Atichasari Anna Sofia , Kristanti Kristanti 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh variabel Pembiayaan Murabahah, Pembiayaan Mudharabah dan Pembiayaan Musyarakah terhadap Profitabilitas (ROA) dengan Non Performing Financing sebagai variabel moderasi. Penelitian ini adalah penelitian kuantitatif yang menggunakan data sekunder. Populasi pada penelitian ini yaitu laporan keuangan Bank Muamalat Indonesia periode 2012-2021 sebanyak 40 laporan keuangan. Teknik pengambilan sampel menggunakan sampling jenuh, dengan jumlah sampling 40 laporan keuangan. Metode analisis data menggunakan analisis regresi linier berganda dengan Moderated Regression Analysis (MRA). Penelitian ini diolah menggunakan software SPSS versi 25. Hasil penelitian ini secara simultan Pembiayaan Murabahah, Pembiayaan Mudharabah dan Pembiayaan Musyarakah berpengaruh secara signifikan terhadap Profitabilitas (ROA). Secara parsial Pembiayaan MurabahahÂ berpengaruh positif terhadap Profitabilitas. Pembiayaan Mudharabah berpengaruh positif terhadap Profitabilitas. Dan Pembiayaan Musyarakah berpengaruh negatif terhadap Profitabilitas (ROA). Berdasarkan uji Moderated Regression Analysis (MRA) secara parsial Non Performing Financing tidak mampu memoderasi Pembiayaan Murabahah, Pembiayaan Mudharabah dan Pembiayaan Musyarakah terhadap Profitabilitas.
Apakah corporate tax avoidance meningkatkan firm value perusahaan di Indonesia?
Authors: Haryanto Sendy Dwi , Ditasari Rollis Ayu , Amalina Nur Ayu 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui apakah pengindaran pajak dapat meningkatkan nilai perusahaan. Â Sampel dalam penelitian ini adalah sebanyak 1700 laporan keuangan periode 2015-2020. Data penelitian ini menggunakan data sekunder dengan menggunakan bantuan software STATA 14.0. Hasil penlitian menunjukkan bahwa tax avoidance dapat meningkatkan nilai perusahaan. Penghindaran pajak merupakan salah satu bentuk strategi perusahaan yang dapat dilakukan oleh manajemen. Hasil penelitian ini mengkonfirmasi terkait teori agensi dimana penghindaran pajak dipandang sebagai metode penghematan pajak pada perusahaan yang memiliki tata kelola yang baik. Penelitian ini diharapkan dapat memberikan manfaat bagi perusahaan untuk menjalankanÂ aktivitas penghindaran pajak sebagai salah satu alat peningkatan nilai perusaahaan di Indonesia.
TÍNH CHẤT QUANG CỦA DUNG DỊCH CACBON NANO CHẾ TẠO TỪ HẠT ĐẬU XANH
Authors: Quang Ngô Khoa , Nguyễn Thị Sương , Phan Thị Khánh Linh , Lê Xuân Diễm Ngọc 
Published: February 2023

Trong nghiên cứu này, chúng tôi tiến hành chế tạo vật liệu hạt cacbon nano (CDs) từ hạt đậu xanh bằng phương pháp thủy nhiệt. Vật liệu CDs chế tạo được có đường kính trung bình d = 13,8 nm. Kết quả khảo sát phổ hấp thụ cho thấy đỉnh đặc trưng ở bước sóng l = 280 nm, ứng với chuyển dịch n → π* của liên kết C=O. Các hạt CDs phát bức xạ dạng phổ rộng trong vùng 320–460 nm khi thay đổi bước sóng kích thích. Hơn nữa, sử dụng quinine sulfate làm dung dịch đối chứng và áp dụng phương pháp so sánh, chúng tôi đã bước đầu tính được giá trị hiệu suất lượng tử của dung dịch cacbon nano (12,18%). Đây là giá trị hiệu suất lượng tử khá cao khi so sánh với hạt cacbon nano chế tạo từ các nguồn nguyên liệu khác.
Perbandingan Kinerja Perusahaan Berdasarkan Variabel-Variabel Kriteria Penilaian Kinerja Unggul (KPKU) (Studi Banding Antara PTPN II dan PTPN IV)
Authors: Manurung Hamzah , Kartika Alda 
Published: February 2023

Menghadapi lingkungan bisnis yang kompleks dan penuh persaingan, setiap instansi pemerintah maupun swasta berusaha untuk meningkatkan kualitas kinerjanya. Dukungan ilmu pengetahuan dan teknologi merupakan informasi yang menjadi penunjang untuk mengarahkan setiap instansi/perusahaan dalam mengelola dan mengukur capaian kerjanya masing-masing. Hal inilah yang mendorong terciptanya penerapan suatu sistem pengukuran kinerja yang tepat dan akurat sebagai alat untuk mengevaluasi kinerja secara keseluruhan. Penelitian ini merupakan penelitian deskriptif dengan membandingkan kinerja Kategori Fokus Pelanggan dan kinerja Kategori Fokus Tenaga Kerja PTPN II dan PTPN IV. Metode pengumpulan datanya melalui pengisian dokumen aplikasi. Tujuan dari penelitian ini adalah menganalisis Perbandingan Kinerja Perusahaan berdasarkan Variabel-Variabel Kriteria Penilaian Kinerja Unggul (KPKU) antara PTPN II dan PTPN IV. Hasil penelitian menunjukkan bahwa secara parsial untuk Kategori Fokus Pelanggan, PTPN II capaian 47,65% dan PTPN IV capaian 55,00% sementara untuk Kategori Fokus Tenaga Kerja, PTPN II memperoleh capaian 60,00% dan PTPN IV memperoleh capaian 52,35%. Secara simultan untuk Kategori Fokus Pelanggan dan Kategori Fokus Tenaga Kerja, PTPN II dan PTPN IV berada di Level 4 (50%-65%) dimana PTPN II memperoleh capaian 53,82% dan PTPN IV memperoleh capaian 53,68% dengan Tingkat Maturitas Proses menunjukkan telah terjadi keselarasan organisasi di PTPN II dan PTPN IV dan Tingkat Maturitas Pembelajaran Organisasi menunjukkan bahwa PTPN II dan PTPN IV telah memiliki strategi dan solusi untuk mengatasi permasalahan karena alat dan sistem perbaikan/peningkatan kinerja telah diterapkan di perusahaan dan menjadi solusi bilamana terjadi tanda-tanda penurunan kinerja.
Kondisi Sosial Ekonomi Petani Padi Sawah dan Nelayan Tradisional di Kawasan Pesisir Kecamatan Pantai Cermin Kabupaten Serdang
Authors: Nainggolan Hotden Leonardo , Ginting Albina , Pakpahan Dahlia 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui kondisi sosial ekonomi nelayan tradisional dan petani padi sawah di kawasan pesisir Kabupaten Serdang Bedagai. Penelitian dilakukan di Kecamatan Pantai Cermin yang ditentukan secara purposive, dengan menggunakan data primer dan sekunder. Data dianalisis secara deskriptif. Berdasarkan hasil penelitian disimpulkan; a) kondisi ekonomi nelayan tradisional lebih baik dibandingkan dengan petani padi sawah berdasarkan; indikator rata-rata pendapatan nelayan yaitu Rp22.847.349,- per tahun lebih besar dari rata-rata pendapatan petani padi sawah Rp17.906.812,- per tahun, b) proporsi pengeluaran konsumsi pangan nelayan sebesar 51,31% lebih kecil dibandingkan dengan petani 64.36%, c) kondisi sosial nelayan tradisional tidak berbeda jauh dengan kondisi sosial petani padi sawah berdasarkan indikator; rata-rata pendidikan anak, d) proporsi pengeluaran untuk kesehatan keluarga nelayan 0,93% dari pendapatan per tahun, lebih kecil dibandingkan dengan petani 1.09%, dan pengeluaran keluarga nelayan untuk pendidikan 13,52% lebih kecil dari proporsi pengeluaran petani padi sawah sebesar 7,37%. Berdasarkan hasil penelitian disarankan agar; a) pemerintah melakukan penyuluhan kepada masyarakat terkait dengan peningkatan penghasilan petani dan nelayan, b) pemerintah memberikan bantuan (beasiswa) kepada anak-anak petani dan nelayan melanjutkan pendidikan ke jenjang yang lebih tinggi, c) pemerintah memberikan bantuan permodalan bagi petani dan nelayan agar kondisi sosial ekonominya lebih baik.
NILAI EKONOMI EKOSISTEM MANGROVE BERDASARKAN BUKAN NILAI PAKAI DI KELURAHAN KARIANGAU KECAMATAN BALIKPAPAN BARAT KOTA BALIKPAPAN
Authors: Jaharudin  , Oktawati Nurul Ovia , Sulistianto Erwan 
Published: February 2023

The objectives of this research was to analyse econimic value from option, axistance and bequest value of mangrove ecosystem at Kariangau Sub District West Balikpapan District Balikpapan City. By using Purposive Sampling method which is the result of taking was to interview collect sample from 40 respondents lived and use mangrove ecosystem.The result shown that community of Karianagu Village still has a high consern on the availability of mangrove ecosystem. mangrove ecosystem economic value consisting of option, existance, and bequest value were Rp.12.702.012.285,00 per year, means if there is damage to the mangrove ecosystem the loss is to be received by Rp12.702.012.285,00 per year, from total mangrove ecosystem area ± 2.037 Ha or Rp.6.235.646,00 per hectare per year.
DAMPAK PERUBAHAN IKLIM PANCAROBA TERHADAP PRODUKSI DAN PENDAPATAN USAHA PENGOLAHAN KERUPUK IKAN GABUS (Channa striata) DI DESA KOTA BANGUN ULU KECAMATAN KOTA BANGUN
Authors: Hanum Vanesa , Abdusysyahid Said , Syafril Muhammad 
Published: February 2023

This study was aimed to know about the; (1) snakehead fish crackers processor’s knowledge and their responses to the climate change issues, as well as the correlation, (2) between its impact before and during the climate change to the production and income of the crackers processing, and; (3) the economic performance of the processing business before and during the climate change issue. Data collection that had been method used in this study were; Primary data, were gathered through observation and interview. And the secondary data, were gathered by the literatures interview. The sampling method that had been done was the sensus methode which all of the population as sample taken, there were eight respondents. And the data analysis that had been used were qualitative and quantitative analysis. Qualitative analyse was measured by the descriptive analysis. While quantitative analyse used non-parametric statistical analysis. The result of this study had shown; that snakehead fish crackers processors already had high knowledge and skills to response the climate change. The correlation between their knowledge and the response of the climate change were negatively strong and insignificant. The impact of the climate-change caused the decline of the both production and income the total revenue had were gathered form 2015 to 2016. They were; 348.634.258,- to Rp 67.931.581,- with RCR value 1,86 and 1,50. The actual condition of the price, sales and production above were the break-even point (BEP) for both years.
Normative Scores on the Norwegian Version of the Mini-Mental State Examination
Authors: Engedal Knut , Benth Jūratė Šaltytė , Gjøra Linda , Skjellegrind Håvard Kjesbu , Nåvik Marit , Selbæk Geir 
Published: February 2023

Background: The Mini-Mental State Examination (MMSE), a simple test for measuring global cognitive function, is frequently used to evaluate cognition in older adults. To decide whether a score on the test indicates a significant deviation from the mean score, normative scores should be defined. Moreover, because the test may vary depending on its translation and cultural differences, normative scores should be established for national versions of the MMSE. Objective: We aimed to examine normative scores for the third Norwegian version of the MMSE. Methods: We used data from two sources: the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) and the Trøndelag Health Study (HUNT). After persons with dementia, mild cognitive impairment, and disorders that may cause cognitive impairment were excluded, the sample contained 1,050 cognitively healthy persons, 860 from NorCog, and 190 from HUNT, whose data we subjected to regression analyses. Results: The normative MMSE score varied from 25 to 29, depending on years of education and age. More years of education and younger age were associated with higher MMSE scores, and years of education was the strongest predictor. Conclusion: Mean normative MMSE scores depend on test takers’ years of education and age, with level of education being the strongest predictor.
Relationship Between Cognitive Performance, Physical Activity, and Socio-Demographic/Individual Characteristics Among Aging Americans
Authors: Dowllah Imtiaz Masfique , Lopez-Alvarenga Juan , Maestre Gladys E. , Karabulut Ulku , Lehker Michael , Karabulut Murat 
Published: February 2023

Background: Physical activity (PA) has emerged as a promising approach to delay Alzheimer’s disease and related dementias, but the optimal intensity of PA to improve cognitive health remains unknown. Objective: To evaluate the association between duration and intensity of PA and cognitive domains (executive function, processing speed, and memory) in aging Americans. Methods: Linear regressions in hierarchical blocks for variable adjustment and the size of effect ( η 2) were analyzed by using the data of 2,377 adults (age = 69.3±6.7 years) from the NHANES 2011–2014. Results: Participants with 3–6 h/week of vigorous- and > 1 h/week of moderate-intensity PA scored significantly higher in executive function and processing speed domains of cognition compared to inactive peers ( η 2 = 0.005 & 0.007 respectively, p < 0.05). After adjustment, the beneficial effects of 1–3 h /week of vigorous-intensity PA became trivial for delayed recall memory domain test scores (β= 0.33; 95% CI: –0.01,0.67; η 2 = 0.002; p = 0.56). There was no linear dose-response relationship between the cognitive test scores and weekly moderate-intensity of PA. Interestingly, higher handgrip strength and higher late-life body mass index were associated with a higher performance across all cognitive domains. Conclusion: Our study supports habitual PA with superior cognition health in some but not all domains among older adults. Furthermore, increased muscle strength and higher late-life adiposity may also impact cognition.
Study on the characteristics of an electromagnetic damping generator
Authors: Li Zequn , Li Desheng , Guo Benzhen , Zhao Tong 
Published: February 2023

This paper proposes an electromagnetic damping generator (EDG), which is a novel downhole generator for the rotary steerable system (RSS). The EDG is designed to solve the problem of unstable voltage output by the RSS generator. The generator is designed by integrating a traditional generator and an eddy current retarder (ECR). The system converts the excess kinetic energy of the EDG rotor into heating energy by the principle of eddy-current braking and resistance heating. The electromagnetic finite element models of the generator part and ECR part are established and solved by computer. The voltage and torque generated by the generator part and the braking torque of the ECR part are predicted. In the bench test, When the input power is 2537 W < P input < 3304 W, the EDG is able to output 300.8 V. When the input power is 3304 W, the output voltage of the ordinary generator is 346 V. The EDG can be adjusted by a decrement of up to 45.2 V to output the rated voltage. The problem of generator output voltage instability in the RSS is solved when mud flow is unstable.