bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caplacizumab (Cablivi)
Authors: CADTH  
Published: July 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses caplacizumab (Cablivi) for injection, powder for solution (11 mg), IV or subcutaneous.
Indication: For the treatment of adults with acquired thrombotic thrombocytopenic purpura in combination with plasma exchange and immunosuppressive therapy.
Diş Çürüklerinin Farklı Yaşam Koşullarına Sahip Köpeklerde Makroskobik Olarak ve Probla İncelenmesi
Authors: ERER Esma 
Published: July 2023

Bu çalışmada farklı yaşam koşullarında bulunan sahipsiz köpeklerdeki diş çürüklerinin evcil köpeklere göre neden daha fazla olduğunun açıklaması amaçlanmıştır. Çalışma Erciyes Üniversitesi Veteriner Fakültesi Cerrahi Anabilim Dalına çeşitli nedenlerle getirilen farklı yaşam koşullarına sahip değişik ırk, yaş ve cinsiyetteki 34 köpeğin dişleri üzerinde gerçekleştirildi. Köpekler yaşam koşullarına göre eşit şekilde sokak ve evcil köpeği olmak üzere iki ana gruba ayrıldı. Olgular dental plak, kalkulus, periodontal hastalık ve abrazyon durumları göz önünde bulundurularak diş çürükleri yönünden probla ve makroskobik olarak incelendi. Çalışmadaki evcil köpeklerin sadece 1’inde çürük gözlenirken, sokakta yaşayan sahipsiz köpeklerin hepsinde lezyonun varlığı kaydedilmiştir. Çürükler en çok maksillar 4. premolar, 1. ve 2. molar dişler ile mandibular dişlerin oklüzal yüzeylerinde ve proksimalinde sarı-kahverengi lekelenmeler şeklinde görüldü. Kanin dişlerde daha az çürükle karşılaşıldı. Dental abrazyona çürük olan dişlerin hemen hepsinde karşılaşıldı. İstatistiksel analiz verilerine göre farklı seviyelerdeki dental plak ve kalkulus ile diş çürüğü arasında zayıf yönde anlamlı bir ilişki olduğu belirlendi. Ancak periodontal hastalık bulunan hayvanların çürükle arasında anlamlı bir fark bulunamadı.
Sonuç olarak köpeklerin yaşam koşullarının diş çürükleri üzerinde istatistiksel olarak son derece anlamlı bir ilişkisinin olduğu belirlendi. Barınma koşulları, beslenme şekilleri, davranış bozuklukları, diş sağlığı ve ağız hijyenin yetersizliği vb. birçok faktör sokak köpeklerinin ağız ve diş sağlığını evcil hayvanlara göre daha fazla etkilediği görüldü. Yaşam koşullarının çürük gelişimi üzerine etkisini inceleyen çalışmaların azlığı nedeni ile bu farklılıklar tam açıklanamadı. Bu sebeple çalışmaların artırılması, hayvanların ağız ve diş sağlığını korumaya yönelik önlemlerin alınması yönünden faydalı olacaktır.
Spatiotemporal variation characteristics of global fires and their emissions
Authors: Fan Hao , Yang Xingchuan , Zhao Chuanfeng , Yang Yikun , Shen Zhenyao 
Published: July 2023

Abstract. Intense regional fires are a common occurrence in the
context of climate warming and have progressively evolved into one of the
major natural disasters in terrestrial ecosystems, posing a serious hazard
to the atmosphere and climate change. We investigated the spatial
distribution, intensity, emission changes, and meteorological differences between
fires in different fire-active and fire-prone regions globally based on
multi-source satellite remote sensing fire data, emission data, and
meteorological data in order to better understand the change trend of fire
activity at multiple spatial and temporal scales. The findings demonstrate
that while the burned area (BA) has decreased slowly over the last 20
years, the burned fraction (BF), the fire count (FC), and the fire
radiative power (FRP) all exhibit pronounced regional and seasonal
variations. The physical characteristics of fires, including the BF, FC, and
FRP, experience greater seasonal variation as latitude increases, with
summer and autumn being the seasons with the most frequent fire occurrence worldwide.
This study also shows that the emissions declined substantially between 2012
and 2020 in northern Canada, Alaska, and northeastern China, whereas it notably
increased in the Siberia region during the same period, primarily due to a
rise in summer emissions. The results based on classification show that the
difference in CO2 produced by fires among regions is relatively small.
Excluding CO2, aerosol emissions (the total of organic carbon (OC), total carbon (TC), black carbon (BC)) ranged
from 78.6 % to 84.2 %, while the least significant air pollutants (the
total of PM2.5, SO2, and NOx) ranged from 5.8 % to 11.7 %. The
abundance of vegetation predominately affects the intensity change in fire
development, while the weather conditions can also indirectly influence the
incidence of fire by altering the growth condition of vegetation.
Correspondingly, the increase in temperature in the Northern Hemisphere's
middle- and high-latitude forest regions is likely the major cause for the
increase in fires and emissions, while the change in fires in tropical
regions was largely influenced by the decrease in precipitation and relative
humidity. This study contributes to the understanding of regional variations
in fire activity and emission variability and provides support for the
control of fire activity across regions and seasons.
Does the syn- versus post-rift thickness ratio have an impact on the inversion-related structural style?
Authors: Tamas Alexandra , Tamas Dan M. , Tari Gabor , Krezsek Csaba , Lapadat Alexandru , Schleder Zsolt 
Published: July 2023

Abstract. Many extensional basins worldwide are modified by subsequent compressional episodes, which lead to inverted structures. The structures associated with the reactivation of pre-existing faults are critically important in the formation of suitable subsurface traps for hydrocarbons. Major concerns regarding inverted structures are the trap integrity and fault seal. In general, the preferred structures have simple four-way closures due to the minor forced folding of the post-rift cover, as opposed to (reverse) fault-related structures, which have a higher risk of breaching. Such reverse-fault-bounded structures have been generally observed in basins with a thick syn-rift fill and a relatively thin post-rift sequence at the time of inversion (Mode I). In contrast, gentle/open forced folds have been described in basins with thicker post-rift sequences than the syn-rift basin fill (Mode II). Five physical sandbox models, coupled with particle image velocimetry (PIV)
analysis, have been performed to address the influence of the syn- versus
post-rift thickness ratio on the inversion-related structural style of the
post-rift cover. The main control on the development of Mode I or Mode II inversion
structures within the post-rift sequence appears to be different due to the
amount of compressional displacement accommodated by the inherited listric
fault and the thickness of the post-rift cover. These observations do have a direct impact on the understanding of the
geo-energy systems associated with inverted structures and are broadly
comparable with natural data examples from Aotearoa/New Zealand, Israel, Romania, and the Republic of Türkiye.
Spaceborne thermal infrared observations of Arctic sea ice leads at 30 m resolution
Authors: Qiu Yujia , Li Xiao-Ming , Guo Huadong 
Published: July 2023

Abstract. Sea ice leads play an important role in the heat exchange between the ocean and the overlying atmosphere, particularly narrow leads with widths of
less than 100 m. We present a method for detecting sea ice leads in the Arctic using high-resolution infrared images from the Thermal
Infrared Spectrometer (TIS) on board the Sustainable Development Science Satellite 1 (SDGSAT-1), with a resolution of 30 m in a swath of
300 km. With the spatial resolution of leads observed by infrared remote sensing increasing to tens of meters, focused on the Beaufort Sea
cases in April 2022, the TIS-detected leads achieve good agreement with Sentinel-2 visible images. For the three infrared bands of the TIS, the B2
(10.3–11.3 µm) and B3 (11.5–12.5 µm) bands show similar performance in detecting leads. The B1 band
(8.0–10.5 µm) can be usefully complementary to the other two bands, as a result of different temperature measurement
sensitivity. Combining the detected results from the three TIS bands, the TIS is able to detect more leads with widths less than hundreds of meters
compared to the Moderate Resolution Imaging Spectroradiometer (MODIS). Our results demonstrate that SDGSAT-1 TIS data at 30 m resolution can
effectively observe previously unresolvable sea ice leads, providing new insight into the contribution of narrow leads to rapid sea ice changes in
the Arctic.
Atendimento odontológico aos pacientes com transtorno do espectro autista (TEA): manejamento, abordagens comportamentais e diretrizes
Authors: Rodrigues Jacqueline Silva Santos , Silva Juliana Ferreira da , Lima Sara de Morais Matazo , Costa Denis Honorato 
Published: July 2023

O transtorno do espectro autista (TEA) corresponde a alteração de comportamentos do indivíduo caracterizado pela ausência de interações sociais, comportamentais e motoras cercado pelo grau do diagnóstico. Nesse cenário é preciso saber o manejo correto do paciente para que o atendimento seja realizado com eficácia. Nosso objetivo é relatar um caso clínico de paciente com TEA apresentando as principais técnicas de manejo comportamental que podem ser utilizadas pelo cirurgião-dentista (CD) durante o atendimento afim de condicionar resultados de qualidade com base no comportamento do paciente. O artigo se baseou no relato de caso clínico de um paciente com TEA atendido na clínica da Universidade Brasil de São Paulo. Foram utilizados artigos científicos e trabalhos acadêmicos, pesquisados no período de 2019 a 2022, encontrados a partir das bases de dados: Scielo, Biblioteca Virtual em Saúde (BVS), Medline e Pubmed. O atendimento do paciente portador do TEA possui dificuldades que são enfrentadas de acordo com a individualidade e nível de espectro de cada paciente, porém se, o CD obter conhecimentos teóricos/técnicos, é possível um tratamento eficaz e com qualidade através do comportamento de cada paciente; Deve atender de forma responsável e avaliar cada caso individualmente, além do uso de materiais adaptados para cada paciente individualmente, e atividades precisamente organizadas e programadas para dar previsibilidade e diminuir a ansiedade da pessoa com TEA. Já que a má adaptação dos conhecimentos técnicos aplicados à um paciente autista dentro de um consultório odontológico pode lhe causar danos tanto para a saúde bucal e mental.
upaya UPAYA PENINGKATAN KETRAMPILAN ISTIMA’ SISWA MELALUI LOMBA GHYNA ARABY
Authors: Istiqomah Istiqomah , Mufidah Nuril 
Published: July 2023

Ghyna Arabi is a contest of singing Arabic songa. The purpose of this research is to find out the students' Istima Skills Improvement through the Ghyna Arabi Contest. This research is a descriptive qualitative research with observation, interviews and documentation as the data collection methods. The results of the study shows that there is an increasing of students' istima skills. It can be shown by the achievement of learning objectives of istima skill.
غينا عربي تغني الأغاني باللغة العربية. الهدف من هذا البحث هو معرفة لتطور مهارة الإستماع الطلاب من خلال مسابقة غينا عربي. هذا البحث هو بحث وصفي نوعي باستخدام طرق جمع البيانات الملاحظة والمقابلات والتوثيق.نتائج هذا البحث أن هناك تطور في مهارة الإستماع الطلاب، ويتضح ذلك من خلال تحقيق أهداف التعليم مهارة الإستماع.
فعالية الوسائل السمعية البصرية على تطبيق القاعدة الإملائية للفصل الأول المكثف معهد الأمين الإسلامي برندوان
Authors: Rahman Abdul , Kirom Abdul 
Published: July 2023

لطالما كان معهد الأمين الإسلامي برندوان علما يشار إليه بالبنان في التربية والتعليم، وتحديدا في تعليم اللغة العربية لطلابها، ولما يجب عليه أن يكون متعلم اللغة العربية من الكمال من حيث المهارات اللغوية الأربع وبالأخص مهارة الكتابة التي نفذت من خلال مادة الإملاء.
انطلاقا من المشاكل التي يعاني منها الطلبة كانت في المدارس الإسلامية في مادة الإملاء المذكورة، واستنادا إلى نتائج المراقبة التي قام بها الباحث أن طريقة التدريس الروتينية لم تتغير منذ القدم، وهذا سبب فادح في تكوين الطلبة غير ماهرين في كتابة العربية صحيحا. أراد الباحث أن يستخدم إحدى الوسائل التعليمية الحديثة في تعليم مادة الإملاء أي الوسائل السمعية البصرية حيث أنها تملك عدة مميزات أهمها سهولة حمل ذهن واهتمام التلاميذ للتركيز مع الدرس. أهداف هذا البحث هي: معرفة فعالية استخدام الوسائل السمعية البصرية على تطبيق القاعدة الإملائية. ومعرفة مدى فعالية استخدامها على تطبيق القاعدة الإملائية لطلبة الفصل الأول المكثف بتربية المعلمين الإسلامية معهد الأمين الإسلامي برندوان. اختار الباحث المدخل الكمي، الذي يستخدم فيه الأرقام. وصفة هذا البحث التجربة، وطريقة جمع البيانات بالامتحان القبلي والبعدي، ومجتمع البحث من طلبة الفصل الأول المكثف وعددهم 130. وطريقة تحليل البيانات باستخدام Independent t- test و Paired Sampel t- test وأظهرت نتائج البحث العلمي بنسبة حسابات البرنامج IBM SPSS 25 التي استخدم الباحث فيها Independent t- test و Paired Sampel t- test والنتيجة المعنوية (2-tailed) هي 0,916 > 0,05 وهذا يدل على أن استخدام الوسائل السمعية البصرية على تطبيق القاعدة الإملائية لطلبة الفصل الأول المكثف بتربية المعلمين الإسلامية معهد الأمين الإسلامي برندوان غير فعالي.
فعالية استخدام وسيلة التعليم بطاقة السحر لترقية فهم القواعد في الفصل العاشر بمدرسة العالية دار العلوم كوريك ساري وارو سيدوأرجو
Authors: Rizki M. Rizal 
Published: July 2023

من المشكلات تعليم اللغة العربية هي تعليم قواعد.كثير من الطلاب يشعرون بصعبة والملل في تعليم قواعد اللغة العربية .إذا كانت في تعليم القواعد يستعمل الطريقة المستخدمة أو بسبب أخطاء في أساليب التدريس. يشعر الطلاب صعبة وصعبة مركبة في الدماغ . حتى قد يكون الطلاب هم لعبوا بأنفسهم أو نامو حين تعليم قواعد اللغة العربية. فلا بد على المدرس أن يعلم الطلاب أن يسعى لاستيفاد كل السهولة الموجودة حوله مثل وسائل الأوراق. يعني ورق اللعب التي يشرح القواعد حتى يستطيع أن تجلب السرور والرغبة لطلاب في تعليم قواعد اللغة العربية. بهذا الموضوع البحث "فعالية استخدام وسيلة التعليم بطاقة السحر لترقية فهم القواعد تعليم اللغة العربية في الفصل العاشر بمدرسة العالية دار العلوم كوريك ساري وارو سيدوأرجو" يريد الباحث أن يعرف دراجة فعالية باستخدام وسيلة التعليم بطاقة السحر في فهم القواعد. رييال الطريقة (Double Test Double Trial Method) الذي استمر مع تحليل للإحصاء إختبار "t" (رمز فيشر) لتحليل البيانات. ويدلّ نتائج البحث فروقا كبيرا بين فهم القواعد اللغة العربية لطلاّب فرقة التجربيّة وفرقة الضبطيّة. وهكذا يمكن أن يخلص أنّ تطبيق استخدام وسيلة التعليم بطاقة السحر لترقية فهم القواعد تعليم اللغة العربية في الفصل العاشر بمدرسة العالية دار العلوم كوريك ساري وارو سيدوأرجو تكون فعالية.
Effect of extrusion process parameters on pellet crumbliness in fish feed production
Authors: Bektursunova Maya , Sidorova Valentina , Zhiyenbayeva Saule , Mashentseva Natalia , Assylbekova Saule 
Published: July 2023

The article presents the results of studying the pellets crumbliness index of a pilot batch of extruded compound feed for pike-perch. The regimes of extruded pellets fish compound feed production with minimal crumbling were defined using a mathematical model. A 3-factorial central composite design was implemented to obtain a mathematical model of the process of extrudate resulting in the second-degree polynomial. The process influencing factors include the feed mixture moisture W (%), extrusion temperature T (°C) and steam pressure P (MPa). Experimental studies were conducted according to the experimental plan. The experimental data obtained were entered into the planning matrix. Experimental data was processed in a program prepared in Microsoft Excel. As a result, an adequate second-order mathematical model describing the dependence of the crumbliness index on the feed mixture moisture before extrusion, extrusion temperature and steam pressure was obtained. The mathematical model adequacy was tested based on Fisher's variance ratio. The Fisher criterion is an important statistical tool for verifying the adequacy of the model and analyzing the variance. The analysis of the obtained model and its graphical interpretation are presented. A good extrusion process mathematical model was developed. The fundamental principles of feed mixture processing on a single-screw extruder and the choice of its rational parameters ensure the production of extruded compound feed pellets for pike-perch with minimal crumbling were studied. A minimal crumbling is provided at the following values of the factors - feed mixture moisture before extrusion is 32%, extrusion temperature is 132 °C, and pressure is 0.4 MPa. In the selected levels of factors, the calculated value of extruded pellets crumbling was 1.02%.
OPTIMASI FORMULASI FAST DISINTEGRATING TABLET (FDT) DIFENHIDRAMIN HCL DENGAN AC-DI-SOL SEBAGAI SUPERDISINTEGRANT DAN MANITOL SEBAGAI BAHAN PENGISI
Authors: Raihanah Raihanah , Noval Noval , Tumanggor Agustina Hotma Uli 
Published: July 2023

Difenhidramin HCl adalah obat yang digunakan untuk mengurangi dan menghalangi efek histamin dalam tubuh, untuk mempercepat kerja obat dan meningkatkan efeknya khususnya untuk pasien anak dan lanjut usia maka dibuat FDT agar efek terapi yang dibutuhkan terjadi cepat. FDT dibuat dengan zat aktif Difenhidramin HCl yang dikombinasikan dengan superdisintegrant Ac-Di-Sol dan bahan pengisi Manitol. Penelitian ini untuk mengetahui pengaruh dari kombinasi Ac-Di-Sol dan Manitol yang optimal dalam Formulasi FDT Difenhidramin HCl. Penelitian menggunakan Metode Quasi Experiment Design dengan rancangan Non Equivalent Control Grup. FDT dibuat dengan 5 formulasi berbeda Ac-Di-sol dan Manitol dengan metode kempa langsung kemudian dilakukan evaluasi moisture content, laju alir, sudut diam, kompresibilitas, keseragaman ukuran, keseragaman bobot, kerapuhan, kekerasan, waktu hancur, waktu disintegrasi dan waktu pembasahan. Hasil penelitian dilakukan analis secara Deskriptif dan Simplex Lattice Design menggunakan Software Design Expert Versi 10.0. Evaluasi sifat fisik serbuk menunjukkan seluruh formulasi memenuhi persyaratan moisture content, sudut diam dan kompresibilitas sedangkan sifat alir semua formulasi tidak memenuhi persyaratan. Hasil dari evaluasi sifat fisik FDT dihasilkan memiliki warna putih bersih, tidak berbau, dengan rasa agak pahit. Semua formulasi FDT memenuhi persyaratan keseragaman bobot, kerapuhan, kekerasan, waktu hancur, dan waktu disintegrasi sedangkan hasil keseragaman ukuran dan waktu pembasahan semua formulasi tidak memenuhi persyaratan. Kombinasi dari perbandingan konsentrasi Ac-Di-Sol dan Manitol memiliki pengaruh dari aspek kerapuhan, kekerasan, waktu disintegrasi dan waktu pembasahan. Formulasi 4 merupakan formulasi optimal dengan komposisi 12,5 mg Ac-Di-Sol dan 7,5 mg Manitol dengan nilai desirability 0,953.
Sketch of a New World: US Occupation and the Politics of Childhood in Postwar Austria
Authors: Van Demark Christopher Max 
Published: July 2023

Abstract
Between 1945 and 1955, US policymakers targeted Austrian children with a sweeping propaganda campaign intended to cultivate democratic, free-market sensibilities. Coordinated in the 1950s by the US Department of State’s Information Agency, US occupation authorities used subtle, Austrian-ized propaganda to develop educational and extracurricular programming at a moment of sociopolitical and economic transformation in postwar Austria. Responding to concerns about the moral degradation of children after Nazism and rising instances of youth delinquency, this campaign sought to address the ongoing youth problem by inscribing a set of behaviors—empathy, cooperation, and respect for others—that were amenable to the broader US democratizing mission in Central Europe. This paper examines a series of articles from Eine neue Welt für unsere Jugend (1953), a German-language anthology written by authors from both sides of the Atlantic. The text exposed Austrian young people to the richness of life in the United States by flaunting sociopolitical and cultural achievements that aligned with the aims of postwar reorientation initiatives, including articles on the Boy Scouts, transatlantic pen pal programs, and after-school clubs. By broaching these topics, US policymakers hoped to cultivate democratic sensibilities in Austrian youth—to build a new Austria supportive of Western-style liberalism. Works by prominent historians in the field, including Jaimey Fisher and Reinhold Wagnleitner, help frame this article that explores the transnational dynamics of democratic rehabilitation in miniature as US policymakers grappled with the aftermath of Nazism on the one hand and an escalating Cold War on the other.
The Elements of Style: Aspiration and the Writing Life in the Early Years of Esquire
Authors: Mexal Stephen J. 
Published: July 2023

ABSTRACT
Much of the scholarship on Esquire has focused on the magazine’s ideological fusion of masculinity and capitalism. Many scholars argue that Esquire’s chief accomplishment was to create what was, at the time of its founding in 1933, an entirely new audience of male consumers. Informed by recent research on the philosophy of aspiration, this article expands these readings by recovering the magazine’s 1930s-era interest in writing and authorship. Under the direction of editor Arnold Gingrich, Esquire was an agent of aspiration, promoting a romantic view of authorship that suggested that writing was an accessible pathway to stylish self-improvement.
The Amber Amulet: A Tale of India and England by Louisa May Alcott
Authors: Daniele Transcribed and Edited by Daniela 
Published: July 2023

ABSTRACT
This transcription reproduces the manuscript of an unpublished novella by Louisa May Alcott titled “The Amber Amulet” which develops the thriller “La Belle Bayadère,” published by Frank Leslie in 1870. The text is approximately dated 1886–87.
Iraq War Milblogs: A Social Media History and Call for Preservation
Authors: Schmermund Elizabeth 
Published: July 2023

ABSTRACT
This article examines the rise of war blogging following the September 11 terrorist attacks and argues for greater preservation of these early blogs, particularly those about the Iraq War (2003–11). The rise in so-called milblogs, or blogs written by (typically male) American service members, at first satisfied the American public’s quest for authenticity and transparency in the Global War on Terror. They offer a supposedly uncensored view of a divisive war for a questioning American public and have been largely ignored by scholars. However, these blogs should be preserved, not merely as snapshots of historical moments within the war, but as war narratives that elucidate the experiences of service members and form an important archive for understanding the reach and reception of social media during this time. Thus, while these blogs function within the realm of history, their narratives and reception deserve critical analysis.
Nineteenth-Century Native American Writers, Representativity, and Political Form
Authors: Sorisio Carolyn 
Published: July 2023

ABSTRACT
This review of Mark Rifkin’s 2021 Speaking for the People: Native Writing and the Question of Political Form shows how Rifkin engages contemporary debates within Native American and indigenous studies, including debates about recognition and gender. Rifkin does so in part by examining how nineteenth-century Native American authors defined and represented peoplehood as both they and those they wanted to represent responded to changes in law, policy, and popular perception. The review includes summaries of Rifkin’s chapters on Elias Boudinot, William Apess, Sarah Winnemucca, and Zitkala-Ša.