bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect Of European Union's Implementation Of The Russian Economic Embargo On International Trade Sector
Authors: Rahman Yogi Muhammad , Adeningtyas Widya Jusu , Mega Jaya Belardo Prasetya 
Published: July 2023

This study analyzes effect of European Union's implementation economic embargo on Russia after Russian invasion of Ukraine. Embargoes imposed was stoppage imports of petroleum and natural gas from Russia. This situation impact of circulation oil and natural gas prices on global market because Russia is the world's largest supplier oil and natural gas. The purpose study is to analyze effect of implementation Russian embargo on international trade sector and examine impact implementation embargo sanctions on Russian economy. The research methodology used is normative juridical. The results show that implementation of embargo against Russia will trigger escalation the price of crude oil and natural gas which are becoming scarce on the global market and significantly reduce availability of grain, wheat, barley and corn commodities while for Russia this case cause increase inflation due to Russia lost most of its shares in international markets.
Nurse Managers’ Perception and Practice on the Theory of Technological Competency as Caring in Nursing: A Preliminary Study
Authors: Nakano Yoko , Yokotani Tomoya , Takashima Yoshiyuki , Betriana Feni , Osaka Kyoko , Kataoka Mutsuko , Tanioka Tetsuya , Locsin Rozzano C 
Published: July 2023

In spite of emphasis on patient-centered care and promotion of their quality, shortcomings have been seen in psychiatric care due to lack of compassion. To improve the quality of psychiatric caring in nursing, it is important to develop and implement in-service education based on Locsin’s Technological Competency as Caring in Nursing (TCCN) theory. Objectives to determine psychiatric nurse managers' perception and practice status as a preliminary survey to serve as a resource for in-service psychiatric nursing education. This survey was conducted in August 2022 using the Technological Competency as Caring in Nursing Instrument-Revised for Practice (TCCNI-Repract) scale at "A" psychiatric hospital. Descriptive statistics and Wilcoxon's signed-rank tests were used. Eleven head nurses and assistant head nurses participated in this study. Mean values for the perception dimension of each item of the TCCNI-RePract were high, whereas mean values for practice dimension were low. The results indicated that perception dimension was significantly higher than practice dimension in 21 of 26 items of the TCCNI-RePract. Nurse managers demonstrated a high level of perception of the TCCN theory; however, many practical items scored low. Nurse managers suggested developing a current educational program to inform practice based on the TCCN theory.
Faster Rate of Correction with Distal Femoral Transphyseal Screws Versus Plates in Hemiepiphysiodesis for Coronal-Plane Knee Deformity
Authors: McGinley James , Worrall Hannah , Althoff Claire , Clark Claire , Jo Chan-Hee , Birch John G. , Wilson Philip L. , Ellis Henry B. 
Published: July 2023

Background:Hemiepiphysiodesis (guided-growth) procedures have become the primary method of treatment for coronal-plane knee deformities in skeletally immature patients. Two leading techniques involve the use of a transphyseal screw or a growth modulation plate. However, clinical references for the estimation of correction are lacking, and no consensus has been reached regarding the superiority of one technique over the other. Therefore, the purpose of this study was to compare the rates of correction for distal femoral transphyseal screws and growth modulation plates in age- and sex-matched cohorts with coronal deformities.Methods:Thirty-one knees were included in each cohort on the basis of propensity scoring by chronological age and sex, and radiographic images were retrospectively reviewed preoperatively and postoperatively. Each case was measured for limb length, mechanical axis deviation (MAD), mechanical lateral distal femoral angle (LDFA), and bone age.Results:Both the MAD and LDFA rate of correction significantly differed between the screw and plate cohorts. The MAD rate of correction was observed to be 0.42 ± 0.37 mm/week (1.69 mm/month) in the plate cohort and 0.66 ± 0.51 mm/week (2.64 mm/month) in the screw cohort. The LDFA rate of correction was observed to be 0.12° ± 0.13°/week (0.50°/month) in the plate cohort and 0.19° ± 0.19°/week (0.77°/month) in the screw cohort.Conclusions:The current study provides simple clinical references for the rate of correction of MAD and the LDFA for 2 methods of hemiepiphysiodesis. The results suggest that transphyseal screws may correct coronal knee deformities during the initial treatment stage more quickly than growth modulation plates in distal femoral guided growth.Level of Evidence:TherapeuticLevel III. See Instructions for Authors for a complete description of levels of evidence.
Biocontrol of strawberry Botrytis gray mold and prolong the fruit shelf-life by fumigant Trichoderma spp.
Authors: Fan Qingshuo , Lin Huajie , Hu Yanjing , Jin Jing , Zhang Ruqin , Yan Honghai 
Published: July 2023

Abstract
Objectives
To screen high active VOCs-producing Trichoderma isolates against strawberry gray mold caused by Botrytis cinerea, and to explore their antagonistic mode of action against the pathogen.
Results
VOCs produced by nine Trichoderma isolates (Trichoderma atroviride T1 and T3, Trichoderma harzianum T2, T4 and T5, T6, T7, T8 and T9 identified as Trichoderma asperellum by ITS sequencing in this work) significantly inhibited the mycelial growth (13.9 − 63.0% reduction) and conidial germination (17.6 − 96.3% reduction) of B. cinerea, the highest inhibition percentage belonged to VOCs of T7; in a closed space, VOCs of T7 shared 76.9% and 100% biocontrol efficacy against gray mold on strawberry fruits and detached leaves, respectively, prolonged the fruit shelf-life by 3 days in presence of B. cinerea, completely protected the leaves from the pathogen infection; volatile metabolites of T7 damaged the cell membrane permeability and integrity of B. cinerea both on water agar or on strawberry leaf surface, thereby inhibiting the mycelia growth, conidia germination and the formation of infection pads.
Conclusions
T. asperellum T7 showed high biofumigant activity against mycelial growth especially conidial germination of B. cinerea and thus protected strawberry fruits and leaves from gray mold, which acted by damaging the pathogen’s plasma membrane and resulting in cytoplasm leakage, was a potential biofumigant for controlling pre- and post-harvest strawberry gray mold.
Extensive transcriptome sex-reversal later in life, after developmental low-dose bisphenol A exposure
Authors: Dunder Linda , Lejonklou Margareta , Lind Monica , Melhus Håkan , Lind Lars , Lind Thomas 
Published: July 2023

Abstract
Bisphenol A (BPA) is an endocrine disruptor and exposure to low doses in utero has been associated with the development of metabolic diseases. Previous work indicated that bone marrow (BM) might be extra sensitive to BPA exposure1. Here we investigate how developmental exposure to low levels of BPA affect the BM transcriptome and the blood metabolic profile, together with how it compares to human metabolic syndrome (MetS) using a population-based cohort. The results show an unexpectedly extensive sex-reversal effect on the BM transcriptome from a BPA dose approximately eight times lower than the temporary European Food Safety Authority (EFSA) human tolerable daily intake (TDI) dose, similarly as a 100-times higher dose, considered safe in 2015(2). BPA appeared to induce, in males, while repress in females, gene expression in general and in T cells in particular, resulting in a hypometabolic cancer-like state in females and a hypermetabolic autoimmunity-like state in males, with a blood metabolic profile that significantly overlaps with human MetS. We conclude that developmental low-dose BPA exposure can cause extensive sex-reversal of transcription together with a sex-specific metabolic syndrome later in life, possibly through effects on T cell activity. Our study provide biologically plausible and convincing evidence for significant effects from low-dose BPA exposure3 and support the proposed substantial lowering of the human BPA TDI by EFSA4.
Pharmaceutical Services Management Capacity and the Municipal Socioeconomic Scenario: Persistent Inequalities
Authors: Faraco Emilia Baierle , Rover Marina Raijche Mattozo , Cunha Luana Niederauer Oliveira Leal da , Leite Silvana Nair 
Published: July 2023

Abstract

Background Although access to essential medicines means resolution for most health conditions in primary health care, ensuring it is still a complex challenge for all health systems. Recent studies show that fair access to medicines must be determined by health care needs, considering the variables in the socioeconomic environment. In this context, despite advances, weaknesses in the development of pharmaceutical services persist, strongly related to management capacity. The study investigates the relationship between the management capacity of Pharmaceutical Services and socioeconomic indices in Brazilian municipalities, analysing which contextual factors are involved in its development.Methods Data from a cross-sectional exploratory study at national scale and indicators developed by Faraco et al. were used to define the capacity of Pharmaceutical Services management. Pearson’s chi-square test and multivariate analysis were performed to associate Pharmaceutical Services management capacity with socioeconomic indices of each municipality. These socioeconomic indices were collected from public database platforms.Results The results prove significant relationships between management and socioeconomic indicators, suggesting that Pharmaceutical Services management capacity is influenced by the environment in which it operates. This study shows municipalities with better management capacity results were those with better socioeconomic indices, better health system conditions and structure, reflecting a greater number of professionals, greater participation of popular social control and use public resources. It is also highlighted that municipalities with a smaller population size and lower socio-economic indices have less ability to manage pharmaceutical services, revealing worsening inequalities for its citizens.Conclusions The existence of an adequate minimum structure, a qualified workforce, service organization, and opportunities for political articulation are essential, as well as conditions for these municipalities to develop and improve their management capacity and for financing based on socioeconomic indicators to become an effective access and adequate use of medicines for the population.
Analysis of Supply-Demand Relations for Ecosystem Services
Authors: Park Yoonsun , Song Youngkeun 
Published: July 2023

Abstract
Ecosystem services play a crucial role in promoting sustainable development by contributing to human well-being. Achieving sustainable development necessitates a balance between the supply and demand for ecosystem services. We performed a factor analysis using ecosystem service measurement results to assess ecosystem service supply and national statistical data representing socioeconomic factors for ecosystem service demand. The analysis results for Gyeonggi-do are as follows: ecosystem service supply was categorized into mixed service provision (factor 1), food supply (factor 2), and phosphorus retention service (factor 3). Ecosystem service demand, based on socioeconomic factors, was divided into shrinking cities (factor 1), densely populated areas (factor 2), and economically active areas (factor 3). Balanced local governments were identified in Goyang, Osan, Paju, Pyeongtaek, Pocheon, Yeoju, Siheung, and Guri, while unbalanced local governments were found in Suwon, Hwaseong, Yongin, Gwangju, Yeoncheon, Yangpyeong, and Namyangju. Furthermore, we propose a management plan to maintain balance between the demand and supply of ecosystem services. Our analysis method and results are applicable to various local governments, providing an invaluable resource for maintaining the balance between ecosystem service supply and demand.
The LOG-after French Childhood Cancer Cohort : acute to long-term follow-up. Methodology of the LOG-after cohort, a database to help in the medium- and long-term care of patients. A GOCE study (Grand Ouest Cancers de l’Enfant, Childhood Cancer, West France) plus other French hospitals
Authors: Chauvet Sophie , Bertrand Amandine , Carausu Liana , Delehaye Fanny , Lejeune Julien , Rouger Jérémie , Schneider Pascale , Thomas Caroline , Millot Frédéric , Claude Line , Leseur Julie , Missohou Fernand , Supiot Stéphane , Bihannic Nathalie , Debroise Isabelle , Jeanneaud Carole , Lebreton Esther , Roumy Marianne , Vincent Melissa , Gandemer Virginie , Pellier Isabelle , Demoor-Goldschmidt Charlotte , Aguerris Les Aguerris association Les , Veillon Pascal , Esvan Maxime , Leonard Mathilde 
Published: July 2023

Abstract
Background
Treatment summary and a personalized survivorship care plan based on internationally approved, organ-specific follow-up care recommendations are essential to preserve health and quality of life. Cohorts have made significant contributions to the understanding of early mortality, somatic late complications, and psychosocial outcomes among childhood cancer survivors. New treatment protocols have the goal to increase the cure and reduce the potential risk and severity of late effects.
Therefore, pursue such databases with modern treatments are necessary.
Construction and content
In the GOCE network, in a participative approach, we developed the LOG-after medical tool, on which health data are registered and can be extracted for analysis. This tool is hosted on a web server, which is health data host certified and several interfaces have been developed depending on the user’s profile. Here we present the construction of the software, the results of the feasibility/satisfaction study with a descriptive analysis.
Utility and discussion
The database contains data of 2558 patients of which for 1702, a tumor bank exists (66.54%). The average treatment start period was April 2015 (ranging from December 1967 to November 2022; 118 patients were treated before 2012 and registered retrospectively when seen in long-term foloow-up consultations or for another cancer since November 2021). When questioned about their satisfaction of the tool, all health care professionals were satisfied. Access to the patient interface is currently open to 124 former patients. This was initially offered to 30 former patients, older than 15 years, affected by the disease within the last 5 years, who agreed to test it. All patients were satisfied with the tool, with an interest to test it in the long-term. Some of them testified to a decrease in mental load, as this verbatim : "I feel lighter. I allow myself to forget, I know I will get a notification when the time comes." Conclusions
Freely available to all users, LOG-after enables (1) help with suggesting a personalized survivorship care plan for middle or long-term follow-up, (2) link with general practitioner, (3) empowerment of the patient, (5) an export of health data for analysis.
Database URL for presentation: https://youtu.be/2Ga64iausJE
Inheritance of RAPD and ISSR markers in hybrid derivatives of inter-specific coffee hybrid (Coffea congensis Froehner x Coffea canephora Pierre): Implications on genetic improvement and plant variety protection
Authors: Kumar Deepanshu , Nanthini Bharatha , Rao Surya Prakash , Krishnan Youvashree , Sethuraman Thilaga , Doss Ganesh 
Published: July 2023

Abstract

An inter-specific hybrid involving Coffea congensis x Coffea canephora is popularly known as C x R coffee hybrid in India. This hybrid was developed with the primary objective of reducing the plant size for high density cultivation and also to improve the coffee beverage quality. Though this hybrid is popularly cultivated in India, segregation of this hybrid due to cross pollination either within the hybrid or with other diploid species of Coffea is one of the major problems to achieve seed purity and higher yield. To utilize DNA marker assisted selection (MAS), two dominant DNA markers (RAPD and ISSR) were analyzed for their utility. About 24 RAPD and 15 ISSR primers were tested for screening the effective primers and only three RAPD and five ISSR primers were found suitable for discriminating the parent. These selective RAPD and ISSR primers produced nine and 23 polymorphic bands respectively with size range of 400 bp – 1200 bp in RAPD and 100 bp – 2000 bp in ISSR. Species specific RAPD and ISSR markers were found in female (Coffea congensis) and male (Coffea canephora) parent of the hybrid and certain of these RAPD and ISSR markers and they are found to inherit into F1 and backcross progenies. The primers for suitability for marker assisted selection were evaluated with parameters such as Polymorphic information content (PIC), effective multiplex ratio (EMR), marker index (MI) and resolving power (RP). Importance of these markers in genetic improvement of this hybrid is discussed.
Theoretical Study on Dynamic Stability of High Bridge Piers Under Near-Fault Earthquake
Authors: An Wenjun , Zhou Ping , Kang Meilan , Liu Yihong , Zhou Lin 
Published: July 2023

Abstract
Select a double span box girder bridge as the analysis model, the vibration control differential equation of ultra-high pier is established, solved by the Runge-Kutta method with variable step length, combined with B-R motion criterion, the dynamic response of ultra-high pier induced by vertical seismic excitation is calculated, and the instability mechanism is studied. Theoretical analysis shows that for high piers, ignoring the bidirectional coupling effect will underestimate the dynamic response of piers. The vertical seismic excitation results in the increase of the axial pressure of bridge pier, which will increase the horizontal deformation of pier. The separation of the main beam and bridge pier will change the extreme deformation value of the bridge pier and increase the risk of pier instability. It has important guiding significance for the theoretical analysis and engineering practice of dynamic instability of ultra-high pier.
Challenges and solutions in developing an objective and structured clinical examination for complementary and integrative medicine: a qualitative study
Authors: Jeong Aram , Lee Hye-Yoon , Shin Sangwoo , Im Sunju 
Published: July 2023

Abstract
Background
The growing prevalence of chronic diseases emphasizes the importance of multidisciplinary and integrative medical care, which considers various factors in the diagnosis and treatment processes. Therefore, training and evaluation on information gathering, physical examination, and patient education for ideal integrative medical care are necessary. An objective and structured clinical examination (OSCE) is widely used in medical education as a tool for evaluating overall clinical performance. This study developed OSCE modules for ideal complementary and integrative medical care practice in Korea. We report the problems and solutions that occurred during this process, as well as future tasks.
Methods
A total of 21 OSCE modules were developed according to 3 different diseases for each of the 7 clinical presentations (CP). Seven clinical experts developed the OSCE modules in each specialized field. Quality control was conducted through repeated feedback from two medical education experts and a standardized patient educator (SP educator). Analysis of the contents of each feedback, a survey of the 7 clinical experts, weekly meetings, and a focus group interview (FGI) was conducted to derive the challenges and possible solutions. Self-evaluation of OSCE development competency and importance-performance analysis (IPA) were conducted for the 7 experts after the main development process.
Results
Seven main themes and 18 subcategories were extracted. The main challenges of developers were categorized into “case,” “test situation,” “post-encounter note,” “checklist,” “scenario,” “format,” and “pattern identification.” During module development, they solved these challenges through discussions among developers and medical education experts. All solutions were categorized into 33 codes. Our survey found their competency in all items to be better than before development, and that they considered pattern identification (PI) the greatest challenge due to its ambiguity.
Conclusion
We found that the more OSCE modules the developers worked on, the more their competency was improved. However, they faced many challenges when developing the modules, which they resolved through discussions on the project. For further effective OSCE module development, we note that social and college-level support should be provided in the form of standardized schemas and human and spatial resources.
Implementation of new technologies designed to improve cervical cancer screening and completion of care in low-resource settings: A case study from the Proyecto Precancer
Authors: Gilman Sarah D. , Gravitt Patti E. , Paz-Soldán Valerie A. , Group Proyecto Precancer Study 
Published: July 2023

Abstract
Background
This case study details the experience of the Proyecto Precancer in applying the Integrative Systems Praxis for Implementation Research (INSPIRE) research methodology to guide the co-development, planning, implementation, adoption, and sustainment of new technologies and screening practices in a cervical cancer screening and management program in the Peruvian Amazon. We briefly describe the theoretical grounding of the INSPIRE framework, the phases of the INSPIRE process, the activities within each phase, and the RE-AIM outcomes used to evaluate program outcomes.
Methods
Proyecto Precancer iteratively engaged over 90 stakeholders in the Micro Red Iquitos Sur (MRIS) health network in the Amazonian region of Loreto, Perú through the INSPIRE phases. INSPIRE is an integrative research methodology grounded in systems thinking, participatory action research, and implementation science frameworks such as the Consolidated Framework for Implementation Research. An interrupted time-series design with a mixed-methods RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) evaluation framework was used to examine the adoption of molecular-based primary cervical cancer screening using HPV-testing (including self-sampling), with direct treatment after visual inspection with portable thermal ablation at the primary level.
Results
The participatory and system-thinking-oriented approach led to rapid adoption and successful implementation of the new cervical cancer screening and management program within 6 months, using an HPV-based screen-and-treat strategy across 17 health facilities in one of the largest public health networks of the Peruvian Amazon. Monitoring and evaluation data revealed that, within 6 months, the MRIS had surpassed their monthly screening goals, tripling their original screening rate, with approximately 70% of HPV-positive women reaching a completion of care endpoint, compared with around 30% prior to the new CCSM strategy.
Conclusions
Proyecto Precancer facilitated the adoption and sustainment of molecular-based primary cervical cancer screening using HPV-testing (including self-sampling), with direct treatment after visual inspection with portable thermal ablation at the primary level and the de-implementation of existing visual inspection-based screening strategies and colposcopy for routine precancer triage at the hospital level. This case study shows how PP used implementation science approaches to guide the adoption of a new screen-and-treat strategy in the Peruvian Amazon, while facilitating de-implementation of older screening practices.