bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combining Artificial Immune System and Clustering Analysis: A Stock Market Anomaly Detection Model
Authors: Close Liam 
Published: August 2023

<p>As online trading systems have increased the amount of high volume, real-time data transactions, the stock market continues to have increased vulnerability to attacks. The goal of this project is to detect these attacks based on normal trade behavior using an Artificial Immune System (AIS) approach combined with clustering algorithms. The AIS approach is inspired by its proven ability to handle time-series data as well as its ability to detect abnormal behavior while only being trained on regular trade behavior. These two main points are important as the models need to be able to adapt over time to adjust to normal trade behavior as it evolves and also due to confidentiality and data restrictions, real-world manipulations are not available for training. This proposed research work discovers a competitive alternative to the leading AIS approach and investigates the effects of combining AIS with clustering algorithms including Kernel Density Estimation, Self-Organized Maps, Density-Based Spatial Clustering of Applications with Noise, Cluster-Based Local Outlier Factor, and Spectral clustering. The best performing solution achieves leading performance in terms of many common clustering metrics including Area Under the Curve, False Alarm Rate, False Negative Rate, and Computation Time. </p>
Signal and System Minimum Mismatch Modeling (3M) with Order Selection Analysis
Authors: Nassif Farah 
Published: August 2023

<p>In the data-driven modeling of linear, time-invariant structures, the choice of the number of parameters (order selection) is critical. It is known that the modeling error, resulting from the maximum likelihood estimate, cannot be directly used for order estimation as this error is a monotonically decreasing function of model order. The most well-known order selection methods, including Akaike information criterion (AIC), Bayesian information criterion (BIC), and minimum description length (MDL), propose an additive penalty term to the modeling error. A more recently proposed method, reconstruction error minimization (REM) concentrates on a different error to provide optimal order selection using a statistical learning approach. A closed-form expression of REM has been provided for the order selection in linear models, including finite impulse responses and has shown superiority over other order selection methods. The existing method of REM calculation uses a Gaussian approximation of the Chi- squared distribution. This work first provides the exact modeling of REM using the Chi-squared distribution. Next, the use of REM is extended for all-pole modeling and pole-zero modeling. For autoregressive (AR) order selection, a method denoted by minimum mismatch modeling (3M) is introduced. It has also been shown that REM is a special case of 3M. Simulation results show the advantages of the proposed method over the existing order selection methods by avoiding overparametrization or underpamaterization in favour of mean squared error (MSE) minimization. In addition, a practical application of eye blink artifact removal from electroencephalogram (EEG) data shows that the proposed method efficiently models the true background EEG while eliminating artifacts efficiently. Furthermore, the application of 3M for EEG sleep-stage classification enabled the classification process to be automated. It is worth mentioning that the use of 3M shows that different sleep-stages have different orders, which can be further used as a feature for classification. </p>
Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate)
Authors: Noviana Dian , Syarifah Mustika Chasanatusy , Gumilang Retna , Bintarti Tri Wahyuni 
Published: August 2023

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax.
Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa.
Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05.
Conclusion: Statistically it can be concluded that there is no effect of the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Pertumbuhan Optimal dengan Pijat dan Spa Bayi
Authors: Jayatmi Irma , Fatimah Jesy 
Published: August 2023

Tujuan pengabdian kepada masyarakat ini adalah Tumbuh Kembang Optimal pada bayi 6-12 bulan dengan Pijat dan SPA Bayi di Posyandu Kenanga Cilebut Bogor Tahun 2019. Kegiatan pengabdian kepada masyarakat ini menggunakan metode dengan melakukan terapi pemijatan dan baby spa yang berjumlah 20 bayi terdiri dari 10 bayi kelompok baby spa (spa bayi) dan 10 bayi kelompok baby massage (pijat bayi). Pengukuran pertumbuhan berdasarkan berat badan dan panjang badan sedangkan pemantauan perkembangan menggunakan Kuesioner Pra Skrining Perkembangan (KPSP). Hasil pengabdian ini menunjukkan bahwa beda rata-rata berat badan setelah baby massage didapatkan hasil 9.020 gram dan setelah baby spa didapatkan 10.580 gram dengan p value 0,002, sedangkan beda rata-rata panjang badan setelah baby massage didapatkan hasil 74.90 cm dan setelah baby spa didapatkan 78.80 gram dengan p value 0,017 dan rata–rata perkembangan pada kelompok baby massage 8.95 lebih rendah dibandingkan dengan kelompok baby spa sebesar 12.05, nilai p value sebesar 0.121. Hasil pengabdian ini diharapkan dapat meningkatan pengetahuan pada ibu tentang pentingnya Baby Spa untuk meningkatkan pertumbuhan (berat badan dan panjang badan) bayi, sedangkan untuk perkembangan bayi dapat melakukan stimulasi baby massage dan baby spa.
Promosi Kesehatan Senam Hipertensi Pada Pasien Usia Lanjut Di Kelurahan Srengseng Sawah
Authors: Rokhmiati Eka , Agustina Marisca , Sarwili Indri 
Published: August 2023

Promosi Kesehatan merupakan cara yang paling efektif jika dibarengi dengan kegiatan. Kegiatan untuk promosi kesehatan pada penyakit tidak menular yaitu Hipertensi yang banyak di derita oleh lanjut usia (lansia). Tujuan pengenalan Senam hipertensi termasuk terapi non farmakologi untuk menurunkan tekanan darah. Senam ini dapat menurunkan tekanan darah, jika dilakukan 3 kali dalam seminggu secara berurutan (senin, rabu dan sabtu) disertai kedisiplinan. Pengukuran tekanan darah mengunakan alat spigmanometer digital yan telah terkalibrasi. Kegiatan dimulai dengan terlebih dahulu dilakukan pengukuran tekanan darah sebelum senam. Setelah kegiatan senam berlangsung, maka dilakukan pengukuran tekanan darah setelah jeda 10 menit. Hasil pengukuran untuk sistole penurunan 5-20 Mmhg, yaitu sebanyak 21 lansia (100%). Penurunan untuk diastole 9-20 Mmhg, yaitu sebanyak 9 lansia (43%). Hal ini membuktikan kegiatan senam hipertensi bagi lansia sangat bermanfaat untuk menjadi sehat dan mengontrol tekanan darah.
Pelatihan Senam Hipertensi Pada Lansia
Authors: Elviana Neneng , Astuti Yuli , Fandizal Muhammad , Sani Dhien Novita , Safari Uum , Riani Nova , Irsan Irsan 
Published: August 2023

Penyakit Hipertensi pada lansia dapat mempengaruhi kualitas hidup. Penyakit ini menyebabkan berbagai komplikasi yang membutuhkan banyak biaya, oleh karena itu senam Hipertensi dapat membantu menurunkan komplikasi dari Hipertensi. Tujuan pengabdian masyarakat ini agar masyarakat khususnya para lansia mengetahui dan menerapkan cara melakukan senam Hipertensi. Mitra pengabdian masyarakat ini yaitu lansia di RT 09 yang dilakukan melalu pendidikan dan pelatihan. Setelah kegiatan diperoleh peningkatan pengetahuan peserta dari 61,7% menjadi 82,3% diakhir kegiatan. Tekanan darah turun sebanyak 10mmHg tekanan darah Sistol dan 5mmHg tekanan darah diastol setelah dilakukan senam Hipertensi. Hal ini membuktikan pentingnya penyuluhan kesehatan melalui pendidikan dan pelatihan untuk menurunkan resiko komplikasi penyakit Hipertensi.
Penyuluhan Kesehatan Mental Sebagai Upaya Peningkatan Kesejahteraan Psikologis Pada Siswa Kelas XII
Authors: Rindu Rindu , Mulachela Zainab Husin , Wardani Indah Sevti , Badriyah Lulu’ul 
Published: August 2023

Kesehatan mental merupakan hal penting untuk menunjang produktivitas dan kualitas kesehatan fisik. Kesehatan mental, khususnya untuk anak dan remaja merupakan masalah yang perlu menjadi fokus utama, mengingat anak dan remaja merupakan generasi yang perlu disiapkan sebagai kekuatan bangsa Indonesia. Tujuan dari pengabdian masyarakat ini untuk meningkatkan pengetahuan remaja terkait kesehatan mental dan juga menjaga kesejahteraan psikologis. Metode yang diterapkan yaitu kegiatan dibagi menjadi 3 tahapan. Tahap I persiapan yang meliputi penentuan jadwal pelaksanaan dan pendataan siswa-siswi, dilanjutkan dengan menyiapkan tempat, alat dan media penyuluhan. Tahap II pelaksanaan, meliputi pre-test, pemberian materi penyuluhan, sesi tanya jawab, dan post-test. Tahap III evaluasi meliputi pengolahan data quisoner pre-test dan post test. Data diolah menggunakan SPSS dengan uji Paired Sample Test. Kegiatan ini dilaksanakan pada 22 Juli 2022 di Aula Yayasan Khasanah Kebajikan dan diikuti oleh 25 siswa kelas XII. Hasilnya menunjukkan terdapat perubahan tingkat pengetahuan siswa pre-tes dan post-tes dengan nilai Sig. (2-tailed) sebesar 0.007.
Kata Kunci: kesehatan mental, penyuluhan, remaja
Implementasi Terapi Olahan Mentimun Dan Terapi Musik Kacapi Suling “Ayun Ambing” Untuk Menurukan Tekanan Darah Penderita Hipertensi Di Cibogor
Authors: Herliana Irma , Susaldi Susaldi , Rahmasari Isrha 
Published: August 2023

Hipertensi menurut WHO merupakan suatu keadaan dimana peningkatan darah sistolik berada diatas batas normal yaitu lebih dari 140 mmHg dan tekanan darah diastolik lebih dari 140 mmHg. Estimasi jumlah kasus hipertensi di Indonesia sebesar 63.309.620 orang, sedangkan angka kematian di Indonesia akibat hipertensi sebesar 427.218. Pemberian olahan mentimun dan terapi musik kacapi suling “ayun ambing” dapat menjadi salah satu terapi pelengkap penanganan hipertensi. Tujuan pengabdian masyarakat ini adalah memberikan edukasi beserta implementasi kepada masyarakat RW 04 Keluarahan Cibogor mengenai pemanfaatan olahan mentimun dan terapi musik intrumen kacapi suling “ayun ambing” untuk menurunkan tekanan darah pada penderita hipertensi. Sebelum dan sesudah implementasi terapi olahan timun dan terapi musik dilakukan cek tekanan darah kepada masyarakat. Didapatkan hasil dari pelaksanaan pengabdian masyarakat 91,6% peserta terdapat penurunan tingkat tekanan darah setelah diberikan olahan timun dan terapi musik. Rata-rata terdapat penurunan tekanan diastolik sebesar 18 mmHg dan rata-rata penurunan tekanan sistolik sebesar 3 mmHg. Masyarakat diharapkan mampu membuat minuman olahan dari mentimun atau memprak-tekan cara terapi musik dengan menggunakan inst-rumen kacapi suling “ayun ambing” sebagai pe-lengkap terapi hipertensi. Pemahaman hipertensi harus dimiliki oleh masyarakat secara luas sehingga penyuluhan harus tetap dilakukan secara rutin baik oleh kader atau tenaga kesehatan serta masyarakat harus memperbanyak literasi (membaca informasi terkait).
Penyuluhan Dan Perawatan Instalasi Listrik Rumah Tangga Pada Masyarakat Kelurahan Kastela Kec. Pulau Ternate Kota Ternate
Authors: Rasyid Ramly , Muhammad Mifta , Saifuddin Hafid 
Published: August 2023

Salah satu cara untuk menghindari bahaya listrik adalah dengan instalasi listrik rumah yang baik dan aman. Umumnya, jumlah orang yang mampu untuk memasang dan merawat instalasi listrik di kelurahanÂ Kastela sangat terbatas. Proses pemasangan dan perawatan instalasi listrik bisa dikatakan cukup sederhana, namun ada aspek-aspek yang perlu diketahui masyarakat dalam instalasi listrik, sehingga bisa menghasilkan instalasi yang baik dan aman serta mudah untuk merawatnya. Metode yang digunakan dalam pengabdian ini dilakuka dengan ceramah singkat,Â tanya jawab dan demonstrasi berkaitan dengan perawatan dan pemasangan instalasi listrik kemudian dilakukan evaluasi dengan demikian dapat diketahui apakah ada peningkatan pengetahuan dan keterampilan dalam menerapkan materi penyuluhan yang diberikan. Kegiatan pengabdian ini berjalan susuai dengan yang direncanakan yang hasilnya yaitu meningkatnya pengetahuan masyarakat khususnya peserta penyuluhan dan pelatihan tentang instalasi listrik beserta perawatannya.
Lipid alternations in the plasma of COVID-19 patients with various clinical presentations
Authors: Liang Xiao , Qi Xin , Yang Jin , Wang Xiaorui , Qin Hongyu , Hu Fang , Bai Han , Li Yixin , Zhang Chengsheng , Shi Bingyin 
Published: August 2023

BackgroundCOVID-19 is a highly infectious respiratory disease that can manifest in various clinical presentations. Although many studies have reported the lipidomic signature of COVID-19, the molecular changes in asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals remain elusive.MethodsThis study combined a comprehensive lipidomic analysis of 220 plasma samples from 166 subjects: 62 healthy controls, 16 asymptomatic infections, and 88 COVID-19 patients. We quantified 732 lipids separately in this cohort. We performed a difference analysis, validated with machine learning models, and also performed GO and KEGG pathway enrichment analysis using differential lipids from different control groups.ResultsWe found 175 differentially expressed lipids associated with SASR-CoV-2 infection, disease severity, and viral persistence in patients with COVID-19. PC (O-20:1/20:1), PC (O-20:1/20:0), and PC (O-18:0/18:1) better distinguished asymptomatic infected individuals from normal individuals. Furthermore, some patients tested positive for SARS-CoV-2 nucleic acid by RT-PCR but did not become negative for a longer period of time (≥60 days, designated here as long-term nucleic acid test positive, LTNP), whereas other patients became negative for viral nucleic acid in a shorter period of time (≤45 days, designated as short-term nucleic acid test positive, STNP). We have found that TG (14:1/14:1/18:2) and FFA (4:0) were differentially expressed in LTNP and STNP.ConclusionIn summary, the integration of lipid information can help us discover novel biomarkers to identify asymptomatic individuals and further deepen our understanding of the molecular pathogenesis of COVID-19.
Responses of the microbial community and the production of extracellular polymeric substances to sulfamethazine shocks in a novel two-stage biological contact oxidation system
Authors: Zhou Jia , Chen Tian , Cui Jing , Chen Yan , Zhao Shuai , Qu Jian-Hang , Wang Zitong , Pan Jingshi , Fan Lixin 
Published: August 2023

IntroductionThe biological contact oxidation reactor is an effective technology for the treatment of antibiotic wastewater, but there has been little research investigating its performance on the sulfamethazine wastewater treatment.MethodsIn this study, a novel two-stage biological contact oxidation reactor was used for the first time to explore the impact of sulfamethazine (SMZ) on the performance, microbial community, extracellular polymeric substances (EPS), and antibiotic-resistant genes (ARGs).ResultsThe chemical oxygen demand (COD) and ammonia nitrogen (NH4+-N) removal efficiencies kept stable at 86.93% and 83.97% with 0.1–1 mg/L SMZ addition and were inhibited at 3 mg/L SMZ. The presence of SMZ could affect the production and chemical composition of EPS in the biofilm, especially for the pronounced increase in TB-PN yield in response against the threat of SMZ. Metagenomics sequencing demonstrated that SMZ could impact on the microbial community, a high abundance of Candidatus_Promineofilum, unclassified_c__Anaerolineae, and unclassified_c__Betaproteobacteria were positively correlated to SMZ, especially for Candidatus_Promineofilum.DiscussionCandidatus_Promineofilum not only had the ability of EPS secretion, but also was significantly associated with the primary SMZ resistance genes of sul1 and sul2, which developed resistance against SMZ pressure through the mechanism of targeted gene changes, further provided a useful and easy-implement technology for sulfamethazine wastewater treatment.
Subtle alterations of vestibulomotor functioning in conductive hearing loss
Authors: Manno Francis A. M. , Cheung Pikting , Basnet Vardhan , Khan Muhammad Shehzad , Mao Yuqi , Pan Leilei , Ma Victor , Cho William C. , Tian Shile , An Ziqi , Feng Yanqiu , Cai Yi-Ling , Pienkowski Martin , Lau Condon 
Published: August 2023

IntroductionConductive hearing loss (CHL) attenuates the ability to transmit air conducted sounds to the ear. In humans, severe hearing loss is often accompanied by alterations to other neural systems, such as the vestibular system; however, the inter-relations are not well understood. The overall goal of this study was to assess vestibular-related functioning proxies in a rat CHL model.MethodsMale Sprague–Dawley rats (N=134, 250g, 2months old) were used in a CHL model which produced a &gt;20dB threshold shift induced by tympanic membrane puncture. Auditory brainstem response (ABRs) recordings were used to determine threshold depth at different times before and after CHL. ABR threshold depths were assessed both manually and by an automated ABR machine learning algorithm. Vestibular-related functioning proxy assessment was performed using the rotarod, balance beam, elevator vertical motion (EVM) and Ferris-wheel rotation (FWR) assays.ResultsThe Pre-CHL (control) threshold depth was 27.92dB±11.58dB compared to the Post-CHL threshold depth of 50.69dB±13.98dB (mean±SD) across the frequencies tested. The automated ABR machine learning algorithm determined the following threshold depths: Pre-CHL=24.3dB, Post-CHL same day=56dB, Post-CHL 7 days=41.16dB, and Post-CHL 1 month=32.5dB across the frequencies assessed (1, 2, 4, 8, 16, and 32kHz). Rotarod assessment of motor function was not significantly different between pre and post-CHL (~1week) rats for time duration (sec) or speed (RPM), albeit the former had a small effect size difference. Balance beam time to transverse was significantly longer for post-CHL rats, likely indicating a change in motor coordination. Further, failure to cross was only noted for CHL rats. The defection count was significantly reduced for CHL rats compared to control rats following FWR, but not EVM. The total distance traveled during open-field examination after EVM was significantly different between control and CHL rats, but not for FWR. The EVM is associated with linear acceleration (acting in the vertical plane: up-down) stimulating the saccule, while the FWR is associated with angular acceleration (centrifugal rotation about a circular axis) stimulating both otolith organs and semicircular canals; therefore, the difference in results could reflect the specific vestibular-organ functional role.DiscussionLess movement (EVM) and increase time to transverse (balance beam) may be associated with anxiety and alterations to defecation patterns (FWR) may result from autonomic disturbances due to the impact of hearing loss. In this regard, vestibulomotor deficits resulting in changes in balance and motion could be attributed to comodulation of auditory and vestibular functioning. Future studies should manipulate vestibular functioning directly in rats with CHL.
Decoding the EEG patterns induced by sequential finger movement for brain-computer interfaces
Authors: Liu Chang , You Jia , Wang Kun , Zhang Shanshan , Huang Yining , Xu Minpeng , Ming Dong 
Published: August 2023

ObjectiveIn recent years, motor imagery-based brain–computer interfaces (MI-BCIs) have developed rapidly due to their great potential in neurological rehabilitation. However, the controllable instruction set limits its application in daily life. To extend the instruction set, we proposed a novel movement-intention encoding paradigm based on sequential finger movement.ApproachTen subjects participated in the offline experiment. During the experiment, they were required to press a key sequentially [i.e., Left→Left (LL), Right→Right (RR), Left→Right (LR), and Right→Left (RL)] using the left or right index finger at about 1 s intervals under an auditory prompt of 1 Hz. The movement-related cortical potential (MRCP) and event-related desynchronization (ERD) features were used to investigate the electroencephalography (EEG) variation induced by the sequential finger movement tasks. Twelve subjects participated in an online experiment to verify the feasibility of the proposed paradigm.Main resultsAs a result, both the MRCP and ERD features showed the specific temporal–spatial EEG patterns of different sequential finger movement tasks. For the offline experiment, the average classification accuracy of the four tasks was 71.69%, with the highest accuracy of 79.26%. For the online experiment, the average accuracies were 83.33% and 82.71% for LL-versus-RR and LR-versus-RL, respectively.SignificanceThis paper demonstrated the feasibility of the proposed sequential finger movement paradigm through offline and online experiments. This study would be helpful for optimizing the encoding method of motor-related EEG information and providing a promising approach to extending the instruction set of the movement intention-based BCIs.