bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Case of Warthin Tumor Highlighting the Diagnostic Dilemmas Encountered
Authors: Shrivastav Gita Gangadharan , Aiyer Hema Malini , Rawat Garima 
Published: May 2023

Introduction: Warthin’s tumour (WT) previously known as papillary cystadeno-lymphomatosum is the most frequent ‘monomorphic’ adenoma of the major salivary glands, representing about 2–15% of all parotid tumours. It is a benign epithelial salivary gland neoplasm affecting elderly individuals and commonly involves the inferior pole of parotid glands. Fine needle aspiration cytology is considered the first diagnostic approach for salivary gland lesions; however, the cytological findings in Warthin tumor can be dubious many a times.
Case Presentation: We present a case of a female in sixth decade of life with left neck swelling which mimicked a necrotic lymph node on imaging and turned out to be Warthin tumor.
Conclusion: In the present paper, we discuss the diagnostic dilemmas faced in a case of warthin tumor.
Biochemical Characterization of Chickpea (Cicer arietinum L.) Genotypes
Authors: Rajput Shrishtika , Jain Sudhanshu , Tiwari Sushma , Barela Akash , Chauhan Shailja , Tiwari Prakash Narayan , Gupta Neha , Sikarwar R. S. , Tripathi Niraj , Tripathi M. K. 
Published: May 2023

Chickpea (Cicer arietinum L.) is one of the most important legumes in the developed as well as developing countries of the world due to its amazing source of dietary proteins. The present experiment was conducted at Research Farm, RVSKVV, College of Agriculture; Gwalior (M.P.). Forty chickpea genotypes were evaluated during Rabi 2020-21 in Randomized block design with two replications. The samples were analyzed for the analysis of peroxidase, Superoxide Dismutase and some of the key biomolecules like total sugars and proline content. The Total sugar ranged from 16.8 mgg-1 (RVSVT PS-2019- 201) to 24.9 mgg-1 (RVSVT PS-2019- 214), proline varied from 1.49 μmolg-1 (RVSVTK-2019- 104) to 2.91 μmolg-1 (RVSVT PS-2019- 213), superoxide dismutase ranged from 8.2 nmolg-1 (RVSVT PS-2019- 211) to 20.1nmolg-1 (RVSVT PS-2019- 205) and lipid peroxide varied from 1.04 nmolg-1 (RVSVTK-2019-101) to 1.92 nmolg-1 (RVSVTD-2019- 4, RVSVTD-2019- 10). Findings of the present investigation may help to choose better genotypes with useful biochemical contents for future crop improvement.
Coffee Acculturation in Saudi Arabia: Diversifying Local Wisdom and Strengthening Sustainable Economy in Coffee Value Chain
Authors: Maspul Kurniawan Arif 
Published: May 2023

Local wisdom is a valuable heritage of society; its existence maintains the community's identity. Coffee, which is the history of the Arabs, is a priceless heritage and local wisdom of national identity in the Arabian peninsula. Saudi Arabia nevertheless maintains this local wisdom and has strengthened it as a valuable identity. However, with diversification rather than local wisdom itself, it will enrich identity references, in this case with third-wave acculturation, which has become a global trend in the coffee value chain.
This paper is a qualitative descriptive which, through the literature, observations, site visits and interviews, which were analysed, concluded that the acculturation of coffee in Saudi Arabia has become more diversified and strengthens the sustainable economy in the coffee value chain from farm to cup. Moreover, it is envisioned that Saudi Coffee 2022 will be able to mitigate the coffee sustainability challenges that will arise in the next generation.
HEYKEL-İ İNSÂN: KEMÂL PAŞA-ZÂDE’NİN RİSÂLE FÎ ŞAHSİ’L İNSÂN ADLI ESERİNİN OSMANLI TÜRKÇESİ İLE GENİŞLETİLMİŞ BİR TERCÜMESİ
Authors: SAMANCI Metin 
Published: May 2023

Osmanlının zirve çağında şeyhülislamlık görevinde bulunmuş olan Kemâl Paşa-zâde Ahmed Şemseddîn (ö. 1534) aynı zamanda tarihçi ve şairdir. Yazdığı onlarca ilmi eserin yanı sıra edebi eserleriyle hem ilim geleneğimize hem de Türk edebiyatına sağladığı katkılar büyüktür.
Kemâl Paşa-zâde’nin dikkate değer ilmi eserlerinden biri de beden, ruh ve nefsi, kısaca insanın varlık yapısını ele aldığı küçük hacimli ama bir o kadar da yoğun olan Risâle fî Şahsi’l-İnsân başlıklı Arapça risalesidir. Bu çalışmada bu risalenin Osmanlı Türkçesiyle yapılan tercümelerinden biri ele alındı.
III. Murad’ın (ö. 1595) cülusuna sunulan, süslü bir nesir diliyle kaleme alınmış Heykel i İnsân başlığını taşıyan bu tercüme eser, yapılan eklemelerle risalenin orijinalinden hacim bakımından yaklaşık beş katı seviyesine ulaşmıştır. Eserin konusuyla doğrudan ilişkili olmasa bile mütercim konuyu ustaca adalete getirir ve devlet görevlilerinin manevi yolculuklarını (seyr u sülûk) adalete özen göstermekle sağlayabileceklerini vurgular. Devlet adamlarının bir tabip gibi tebaanın hastalıklarını teşhis edip ona göre müdahale etmeleri gerektiği söylenir. Bu gibi eklemeler sonucunda tercümenin bir bakıma siyasetname özelliği gösterdiği de söylenebilir. Baştan sona secili olan bu eserinde mütercim marifet, İslam dininin temel kaynakları (edille-i şer’iyye) konularına da değinmiş ve bu konuda kendi dönemine eleştiriler yöneltmiştir.
Bu çalışmada Arapça eserin bire bir Türkçe tercümesi de yapılmış; bunun yanı sıra çalışmanın ana konusu olan Heykel-i İnsân adlı tercüme ele alınmış, içerik ve üslup bakımından diğer tercümelerle karşılaştırılmıştır.
Нарративы христианизации в формировании коми литературной традиции (XIV – начало XX вв.)
Authors: Лимеров Павел 
Published: May 2023

Специфика изучения процессов формирования национальных литературных традиций сегодня является одним из приоритетных направлений науки о литературе. Преемственность, взаимосвязи и взаимодействия национальных литератур мыслятся как важнейшая проблема литературоведения, определяющая литературу России во всей её полноте. Как отмечают авторы «Предисловия» коллективной монографии «Пермские литературы в контексте финно-угорской культуры и русской словесности» (Ванюшев и др. 2014: 5), «Исследование феномена российской литературы как уникального явления, синтезировавшего в себе философский и нравственный опыт, художественное слово многих народов, – глобальная задача современного литературоведения, решение которой возможно на пути системного изучения промежуточных межлитературных общностей, их внутренних свойств и взаимных отношений». Системное изучение литературной традиции неизбежно предполагает постановку вопроса о её абсолютном начале, о тех когнитивных процессах, которые привели к возникновению литературы. Традиционно считается, что так называемые молодые или «младописьменные» литературы берут своё начало в фольклоре (Ванюшев и др. 2014: 7; Владыкина 2014: 13), при этом не учитывается, что фольклор сам по себе может порождать только фольклорные тексты, а литературное освоение фольклора уже свидетельствует о наличии художественного сознания. В этом смысле актуально изучение самого процесса перехода от фольклорно-мифологического типа сознания к сознанию художественному как к «духовной или ментальной доминанте собственно художественности» (Созина 2001: 9). Толчком для такого перехода справедливо полагается освоение национальной словесностью опыта русской литературы, благодаря которому начиная с середины XIX в. и наиболее интенсивно с первой четверти ХХ в. формируются каноны национальных (и региональных) литературных традиций России.
Determinants of Banking Sector Efficiency in Kenya: Application of Non-parametric Data Envelopment Analysis (DEA) Model
Authors: Ikapel Francis O. , Namusonge Gregory S. , Sakwa Maurice M. 
Published: May 2023

The financial system plays an important role in the economic development and financial stability of a country. Banks play a critical role in facilitating stability of the financial system and economic development. Evaluating the determinants of banking efficiency therefore provides insight to establish the target factors that influence efficiency to facilitate inefficiency identification and elimination.
The study’s objective was to evaluate the determinants of banking sector efficiency in Kenya for the period 2006 to 2017. Secondary data were collected from the annual reports and financial statements of 10 commercial banks listed on the Nairobi Securities Exchange (NSE). The analysis was carried out in two stages. In the first stage, the non-parametric Data Envelopment Analysis (DEA) approach was used to compute the efficiency scores. In the second stage, panel regression analysis was then performed to evaluate the determinants of efficiency. The results showed that Capital Adequacy and Market Capitalization are significant in determining the Efficiency of a bank, p =0.0315< 0.05 and p=0.0253< 0.05 respectively. Further, bank size (p = 0.000< 0.05), capital adequacy (p = 0.0014< 0.05), leverage (p = 0.0000< 0.05) and Liquidity risk (p = 0.0000< 0.05) have a significant effect on Scale Efficiency. Market capitalization (p = 0.5056>0.05) is statistically insignificant in influencing the Scale Efficiency of the bank. From the findings, the study, therefore, concludes that, bank size, capital adequacy, liquidity risk, leverage and market capitalization have a significant effect on bank efficiency. The study recommends that bank managers should focus on improving management quality by ensuring compliance with prudential guidelines issued by the Central Bank of Kenya. Particularly, bank managers should ensure capital adequacy and market capitalization requirements are met since they are found to be the key drivers of efficiency and performance. Further, maintaining an optimal bank size, market capitalization, appropriate liquidity risk and leverage level is significant in guaranteeing improved performance.
Numerical Simulations and Fish Diversity in Relation to Physico-chemical Parameters of Four Aquatic Stations in Badagry Division, Lagos, Nigeria
Authors: Olarinde Mekuleyi Gabriel , Olabode Joseph Olufemi , Senapon Wusu Ashiribo , Akorede Badmos Lateef , Agenuma Anetekhai Martins 
Published: May 2023

Aim: This study investigated common fish assemblages in four aquatic stations (Gbaji, Topo, Agboju and Ajegunle) in relation to physico-chemical parameters of its water and as well simulates numerical values of the physico-chemical parameters for year 2024.
Methodology: Data were collected and computed using standard methods and algorithm machine learning model respectively. Statistical tools employed include ANOVA and Pearson correlation (r) test. All the parameters (except turbidity, chemical oxygen demand and biochemical oxygen demand) were within standard permissible limits.
Results: The results of Pearson’s correlation analysis showed that increase in amount of fish species in the sampling stations was significantly and strongly linked to the decrease in value of biochemical oxygen demand (r = −0.571, P=.05), total dissolved solids (r= −0.696, P=.05) and conductivity (r=−0.882, P<0.01) while increase in number of fish species was significantly and strongly linked to the increase in value of dissolved oxygen(r= 0.991, P=.05). However, salinity (r= 0.387), sulphate (r = 0.212) and turbidity (r= 0.282) had weak positive relationship with the number of fish species. The prediction by the machine learning algorithm modeling system revealed that at Agboju, total hardness would exceed permissible limit in February and September, carbondioxide (C02) in February, May and June, 2024.On the other hand, level of C02 at Ajegunle would exceed permissible limit in January, May, August and September, and total hardness in November, 2024. For both Agboju and Ajegunle, turbidity and chemical oxygen demand level would exceed limits throughout the months in year 2024.
Conclusion: Hence, effects of higher parameters could results in declination of distribution of demersal fish species which often shuttle between the water bottom and surface.
Unsustainable Agricultural Practices as a Driver of Soil Degradation in Santa Sub-Division, North West Region of Cameroon
Authors: Jocien Siyir Kinyuy , Frederick Nfor 
Published: May 2023

This research sets out to investigate unsustainable agricultural practices as a driver of soil degradation in Santa sub-division, North West Region of Cameroon. The major types of agricultural practices studied were bush fallowing, slash-and-burn, shifting cultivation and bush fire. The study assessed the various agricultural activities that have occurred on the environment over time and space. The causes of unsustainable agriculture were identified to be overgrazing, deforestation, climate change and population growth. The study made use of primary and secondary data sources. Major primary data sources included field observation, interviews and administering of questionnaires. Data collected were presented in the form of tables, charts and pictures and subjected to interpretation. A soil test was equally carried out based on some chemical properties on selected sites in Santa sub- division. The findings revealed that unsustainable agricultural practices in this zone contributes to soil degradation. Climate change was seen to have a silver lining in the crop sector. Declining soil fertility and climate change were some of the major problems faced by farmers in Santa. Mixed crop farming, crop rotation, soil management practices and mulching were recommended to limit or stop soil degradation in Santa. Finally, it was recommended that farmers should incorporate more environmentally friendly trees into their farm lands since scattered trees on farmlands improve soil fertility more.
Rational Design and Acoustic Assembly of Human Cerebral Cortex‐Like Microtissues from hiPSC‐Derived Neural Progenitors and Neurons
Authors: Wang Jibo , Qiao Haowen , Wang Zhenyan , Zhao Wen , Chen Tao , Li Bin , Zhu Lili , Chen Sihan , Gu Longjun , Wu Ying , Zhang Zhentao , Bi Linlin , Chen Pu 
Published: May 2023

AbstractDevelopment of biologically relevant and clinically relevant human cerebral cortex models is demanded by mechanistic studies of human cerebral cortex‐associated neurological diseases and discovery of preclinical neurological drug candidates. Here, rational design of human–sourced brain‐like cortical tissue models is demonstrated by reverse engineering and bionic design. To implement this design, the acoustic assembly technique is employed to assemble hiPSC‐derived neural progenitors and neurons separately in a label‐free and contact‐free manner followed by subsequent neural differentiation and culture. The generated microtissues encapsulate the neuronal microanatomy of human cerebral‐cortex tissue that contains six‐layered neuronal architecture, a 400‐µm interlayer distance, synaptic connections between interlayers, and neuroelectrophysiological transmission. Furthermore, these microtissues are infected with herpes simplex virus type I (HSV‐1) virus, and the HSV‐induced pathogenesis associated with Alzheimer's disease is determined, including neuron loss and the expression of Aβ. Overall, a high‐fidelity human‐relevant in vitro histotypic model is provided for the cerebral cortex, which will facilitate wide applications in probing the mechanisms of neurodegenerative diseases and screening the candidates for neuroprotective agents.
High‐Temperature, Reversible, and Robust Thermochromic Fluorescence Based on Rb2MnBr4(H2O)2 for Anti‐Counterfeiting
Authors: Liu Yang , Liu Gaoyu , Wu Ye , Cai Wenbing , Wang Yue , Zhang Shengli , Zeng Haibo , Li Xiaoming 
Published: May 2023

AbstractThermochromic fluorescent materials (TFMs) characterized by noticeable emission color variation with temperature have attracted pervasive attention for their frontier application in stimulus‐response and optical encryption technologies. However, existing TFMs typically suffer from weak PL reversibility as well as limited mild operating temperature and severe temperature PL quenching. PL switching under extreme conditions such as high temperature will undoubtedly improve encryption security, while it is still challenging for present TFMs. In this work, high‐temperature thermochromic fluorescence up to 473 K and robust structural and optical reversibility of 80 cycles are observed in Rb2MnBr4(H2O)2 and related crystals, which is seldom reported for PL changes at such a high temperature. Temperature‐driven nonluminous, red and green light emission states can be achieved at specific temperatures and the modulation mechanism is verified by in situ optical and structural measurements and single particle transition. By virtue of this unique feature, a multicolor anti‐counterfeiting label based on a broad temperature gradient and multidimensional information encryption applications are demonstrated. This work opens a window for the design of inorganic materials with multi‐PL change and the development of advanced encryption strategies with extreme stimuli source.
Modeling SARS‐CoV‐2 True Infections in Catalonia through a Digital Twin
Authors: Fonseca i Casas Pau , Garcia i Subirana Joan , Garcia i Carrasco Victor 
Published: May 2023

AbstractA dynamic view of the evolution of the infections of SARS‐CoV‐2 in Catalonia using a Digital Twin approach that forecasts the true infection curve is presented. The forecast model incorporates the vaccination process, the confinement, and the detection rate, and virtually allows to consider any nonpharmaceutical intervention, enabling to understand their effects on the disease's containment while forecasting the trend of the pandemic. A continuous validation process of the model is performed using real data and an optimization model that automatically provides information regarding the effects of the containment actions on the population. To simplify this validation process, a formal graphical language that simplifies the interaction with the different specialists and an easy modification of the model parameters are used. The Digital Twin of the pandemic in Catalonia provides a forecast of the future trend of the SARS‐CoV‐2 spread and information regarding the true cases and effectiveness of the NPIs to control the SARS‐CoV‐2 spread over the population. This approach can be applied easily to other regions and can become an excellent tool for decision‐making.
Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles
Authors: Tarab‐Ravski Dana , Hazan‐Halevy Inbal , Goldsmith Meir , Stotsky‐Oterin Lior , Breier Dor , Naidu Gonna Somu , Aitha Anjaiah , Diesendruck Yael , Ng Brandon D. , Barsheshet Hagit , Berger Tamar , Vaxman Iuliana , Raanani Pia , Peer Dan 
Published: May 2023

AbstractMultiple myeloma (MM) is a cancer of differentiated plasma cells that occurs in the bone marrow (BM). Despite the recent advancements in drug development, most patients with MM eventually relapse and the disease remains incurable. RNA therapy delivered via lipid nanoparticles (LNPs) has the potential to be a promising cancer treatment, however, its clinical implementation is limited due to inefficient delivery to non‐hepatic tissues. Here, targeted (t)LNPs designed for delivery of RNA payload to MM cells are presented. The tLNPs consist of a novel ionizable lipid and are coated with an anti‐CD38 antibody (αCD38‐tLNPs). To explore their therapeutic potential, it is demonstrated that LNPs encapsulating small interference RNA (siRNA) against cytoskeleton‐associated protein 5 (CKAP5) lead to a ≈90% decrease in cell viability of MM cells in vitro. Next, a new xenograft MM mouse model is employed, which clinically resembles the human disease and demonstrates efficient homing of MM cells to the BM. Specific delivery of αCD38‐tLNPs to BM‐residing and disseminated MM cells and the improvement in therapeutic outcome of MM‐bearing mice treated with αCD38‐tLNPs‐siRNA‐CKAP5 are shown. These results underscore the potential of RNA therapeutics for treatment of MM and the importance of developing effective targeted delivery systems and reliable preclinical models.
Sleep duration in middle childhood and age at menarche
Authors: Zhu Mia Q. , Mora‐Plazas Mercedes , Marín Constanza , Villamor Eduardo 
Published: May 2023

AbstractObjectivePuberty affects sleep phasing. However, it is unclear if sleep duration earlier in childhood could influence the timing of pubertal events. We aimed to assess the association between middle childhood nighttime sleep duration and age at menarche (AAM).MethodsIn a cohort of 819 premenarcheal Colombian girls who were followed annually for the occurrence of menarche, we estimated adjusted hazard ratios (HR) with 95% confidence intervals (CI) for menarche by categories of recommended sleep duration in middle childhood using Cox models. Analyses were stratified by age at sleep assessment.ResultsAmong girls aged 9 to <11 years, compared with girls who slept within recommendations, sleeping above recommendations was related to an adjusted 76% (95% CI: 4%, 198%; p = .04) higher probability of experiencing menarche during follow up. In girls aged ≥11 years, compared with girls who slept within recommendations, sleeping under recommendations was related to an adjusted 42% (95% CI: 5%, 93%; p = .03) higher probability of experiencing menarche during follow‐up. Sleep duration was not associated with AAM in girls aged <9 years at the time of sleep assessment.ConclusionsSleeping above recommendations in girls 9 to <11 years‐old and sleeping under recommendations in girls ≥11 years‐old is associated with earlier menarche.
Synthesis and characterization of improved bio‐based carbon content thermoplastic polyurethane with bio‐aliphatic and petro‐aromatic diisocyanate
Authors: Oh Jiyeon , Kim Young Kwang , Hwang Sung‐Ho , Kim Hyun‐Chul , Jung Jae‐Hun , Jeon Cho‐Hyun , Lim Sang Kyoo 
Published: May 2023

AbstractThe study involved producing green thermoplastic polyurethanes (TPUs) that were either partially or fully bio‐based. This was achieved through a one‐shot polymerization process using a combination of sebacic acid‐polyester polyol, 1,4 butanediol derived from renewable sources, and diisocyanate. The diisocyanate used included bio‐aliphatic pentamethylene diisocyanate (PDI), petro‐aromatic methylene diphenyl diisocyanate (MDI), and a combination of PDI and MDI. Various methods were employed to characterize the newly synthesized TPUs, which had a weight average molecular weight exceeding 120,000 g/mol. Increasing the content of PDI improves the bio‐based carbon content up to about 97% and increases the pyrolysis onset temperature. An increase in MDI content results in a rise in the complex viscosity, tensile strength, and strain. However, a PDI‐based TPU (P/M_100/0) achieved an excellent phase separation with a tensile strength of 20.7 MPa and elongation of 587.2%, comparable to an MDI‐based TPU (P/M_0/100). Overall, this research demonstrates the feasibility of utilizing partially or fully bio‐based TPUs as a substitute for conventional MDI, with potential industrial applications.