bluuebunny/crossref_metadata_2025_split huggingface dataset:
The assessment of the dietary patterns of patients with Crohn’s disease (CD) in remission in Sri Lanka; an outpatient clinic based study
Authors: G Samarasekera T , R Jayatissa , N Fernandopulle , E Gunaratne I , T Harishchandra H D , L Samarasekera G B , Husseinpour Haneigh , Nishad Nilanga 
Published: May 2023

Abstract
Background/Aims: Diet is partly responsible for the exacerbation of symptoms in CD. The assessment of nutritional status and dietary pattern is crucial in CD. Study was designed to describe the dietary patterns of CD patients in remission attending to the gastroenterology clinic in National hospital of Sri Lanka
Methods: A descriptive cross-sectional study was carried out. Demographic, clinical and biochemical data and data on dietary patterns and behaviors were gathered using an interviewer administered questionnaire. Dietary intake was assessed using 24 hour dietary along with a 3 day diet diary. Data were analyzed using Statistical Package for Social Sciences 23.0.
Results: Overall, 50 adult patients including 32 males and 18 females diagnosed with CD were recruited. Mean age (s.d.) of the participants was 39.9 (8.4) years. Forty six percent of the population (n=23) was in normal BMI range while 36% was underweight and 18% was overweight. Majority (49, 98%) were non- vegetarians. Forty nine (98%) patients believed that certain food items worsen their symptoms of CD. The most commonly self-identified dietary triggers for CD relapse were carbonated drinks and red meat. Red meat (86%), Samposha (82%) and peanuts (70%) were identified as the mostly avoided food items. Own experience was the most influential source to prevent relapse (n=45, 90%) followed by medical advice (76%), social media and internet (50%) and family and friends (16%).
Conclusions: Assessment of nutrition status and dietary intake is crucial to optimize dietary intervention with targeted nutrition counseling, to enhance nutritional status in CD patients.
Technology for adaptation: a case study of developing a detailed inventory of drinking water supply technologies along the salinity-affected coastal region of Bangladesh
Authors: Islam Md. Sirajul , Deb Biplob Kumer , Alam Shoeb Reaz , Nishat Ainun 
Published: May 2023

Abstract

The south-western coastal zone of Bangladesh is suffering from an acute crisis of freshwater due to salinity intrusion. First, the extent of the problem and its causes in detail were investigated. Climate change along with a few other anthropogenic impacts are the main causes. Exploring technologies for adaptation to climate change is emphasized today to overcome the problem of climate change impact. The coastal community was found to be already adopting technological measures as an adaptation means. This study developed a detailed inventory of all the available indigenous water supply technology options along the region and categorized them. An analysis of the suitability of the technologies was done, focusing on factors like the state of the technology, convenience in operation, quantity and quality of the supplied water, as well as financial viability or management practice. Both qualitative and quantitative approaches to the study were adopted to collect and analyze the data through extensive field visits, laboratory testing, and secondary data analysis. It is found that in most cases, solutions are on an ad hoc basis, having a lifetime of less than 5 years. In some places, people are gradually moving towards community-based and long-term hi-tech solutions.
Parameters and methods used in flood susceptibility mapping: a review
Authors: Kaya Cagla Melisa , Derin Leyla 
Published: May 2023

Abstract
A correct understanding of the parameters and methods used in flood susceptibility mapping (FSM) is critical for identifying the strengths and limitations of different mapping approaches, as well as for developing methodologies. In this study, we examined scientific publications in the literature using WoS. Although the number of methods used is quite high, the number of parameters used in these methods varies, with a maximum of 21 and a minimum of 5 parameters preferred. It was found that the most commonly used parameter has a preference rate of 97%, but there is no common parameter in 100% of the studies. The methods used for determining flood susceptibility include multi-criteria decision-making (MCDM) methods, physically based hydrological models, statistical methods, and various soft computing methods. Although the use of traditional statistical methods and MCDM methods is already high among researchers, the methods used in flood susceptibility analysis have evolved over the years from traditional human judgments to statistical methods based on big data and machine learning. In the reviewed studies, it was observed that machine learning, fuzzy logic, metaheuristic optimization algorithms, and heuristic search algorithms, which are soft computing methods, have been widely used in FSM in recent years.
Temporal evaluation of surface water quality in semiarid regions: a case study of the Ouled Mellouk dam in north-western Algeria
Authors: Madene Elaid , Boufekane Abdelmadjid , Busico Gianluigi , Meddi Mohamed , Maizi Djamel 
Published: May 2023

Abstract

This work aimed at evaluating the impact of human activity and geology on the surface water quality of the Ouled Mellouk dam (northwestern Algeria). Specifically, methodology aims to assess seasonal variations of several parameters (EC, TDS, pH, SO42−, Cl−, Ca2+, Na+, HCO3−, NO3−, PO43− and Mg2+, organic matter, suspended solids, BOD5, COD) from 2007 to 2013 to define the processes controlling the mineralization and pollution of the surface water. The results show high salinization recorded during the periods of heavy precipitation or flooding, due to leaching of dolomitic limestones and evaporitic deposits from the saliferous formations of the surrounding mountains. High concentrations of NO3−, NO2−, NH4+, and organic matter can instead be attributed to the use of fertilizers in agriculture. Moreover, the PCA application shows that salinization (49.92%), anthropogenic pollution (19.38%) and agricultural pollution (12%) are the most significant degradation factors, respectively. The saturation index of carbonates and gypsiferous minerals shows the carbonates precipitate before the gypsiferous minerals, which allowed the chemical elements coming from the dissolution of gypsum and halite to acquire significant contents. In addition, the evolution of biological oxygen demand and organic pollution shows slight pollution of the dam water.
Current Formulation Strategies to Design Novel Carriers for Targeted Drug Delivery and Management of Infectious Keratitis: A Comprehensive Review on the Present State of the Art
Authors: Sarkar Tumpa , Singh Mohini , Jana Bani Kumar , Mazumder Bhaskar 
Published: May 2023

Objective:
Infectious keratitis is a pernicious disease that affects the anterior segment of the
eye and is one the leading causes of blindness worldwide. This disease may cause severe visual impairment
or permanent vision damage if left untreated.

Discussion:
No doubt there are many conventional drug delivery systems to treat ocular keratitis, yet it is
the fifth leading cause of blindness globally. This is the result of the eye's complex anatomy and barrier
system, which restricts the total ocular contact time of the conventional formulations resulting in underdosing.
The widely used traditional formulations to treat keratitis, like antibiotic eye drops and ointments,
are rendered useless due to less ocular contact time and low therapeutic drug levels at the target ocular
site. The main requirement of the present time is to develop novel drug delivery-backed stratagems to
overcome the shortcomings of conventional formulations, which will reduce the morbidity associated
with infectious keratitis and improve clinical outcomes. It is worth mentioning that there are documented
incidents of Herpetic keratitis of the cornea followed by COVID-19 infection and vaccination.

Conclusion:
This paper is a rigorous review of all the novel drug delivery strategies to combat ocular
keratitis. These future drug delivery strategies will pave the way for the present time researcher and formulation
chemists to develop multi-dimensional novel formulations that are safe, patient-compliant, and
surpass the ocular barriers to maintain therapeutic drug levels in ocular tissues.
Relationship between Subclinical Hypothyroidism and Uremic Pruritis in
Hemodialysis Patients
Authors: Kotb Essam , Mohamed El mancy Ismail , Ghounim Ramadan  Mohamed Ibrahim , Ahmed  Ayoub Hazem Sayed , Rashed AL-Sayed M. , EL-Nasser Waleed S. , Ismail  Hamed Hani , Aladl Aladl Hossam , Sabrh Mostafa , Eliwa Ahmed , Ghamry Esam M. , Abdelhamed Mohamed R. , Mahmoud Tamer M. 
Published: May 2023

Background and Aim:
Uremic pruritus (UP) is one of the most distressing symptoms in hemodialysis (HD) patients. Subclinical hypothyroidism (SCH) is a biochemical condition with high prevalence in HD patients. The present multicentric study aimed to assess the relationship between UP and SCH in HD patients.

Methods:
The present cross-sectional study included 328 HD patients. All patients were submitted to careful history through clinical examination and standard laboratory assessment. Pruritis was evaluated using the pruritis visual analog scale (VAS). Patients were diagnosed with SCH if they had TSH levels above the upper limit of the normal reference range in association with normal free thyroxine (FT4) levels.

Results:
Among the studied patients, there were 196 patients (59.8 %) with UP. Comparison be-tween patients with UP and patients without revealed that patients in the former group had signifi-cantly longer HD duration (median (IQR): 47.5 (27.0-72.5) versus 36.0 (23.0-50.5) months, p  0.001) and lower Kt/v (median (IQR): 1.4 (1.09-1.7) versus 1.54 (1.12-1.91), p = 0.009). Moreover, they had significantly higher ferritin (median (IQR): 653.0 (526.0-800.0) versus 628.0 (470.8-716.0) ng/mL), hsCRP (median (IQR): 12.0 (8.0-14.0) versus 8.0 (6.0-9.0) mg/dL, p  0.001) and TSH levels (median (IQR): 4.34 (1.98-5.2) versus 3.34 (1.9-4.85) μIU/ml) with a significantly higher frequency of SCH (45.9 % versus 28.8 %, p = 0.002). Logistic regression analysis identified hemodialysis duration (OR (95%) CI): 1.02 (1.009-1.028), p  0.001), ferritin levels (OR (95% CI): 1.002 (1.001-1.003), p  0.001), and SCH (OR (95% CI): 0.54 (0.32-0.89), p = 0.016) as significant predictors of UP.

Conclusion:
The present study suggested a possible link between SCH and the development of UP in HD patients.
Nursing Research Priorities based on the Nurse-sensitive Indicators: Scoping Review
Authors: Hakami Afaf , Hussain Fazal , Bakheet Anas , Alghamdi Khalid , AlAtrash Khalid 
Published: May 2023

Background:
Patient-centeredness, safety, and quality of care are major healthcare concerns worldwide. Clinical indicators are essential for monitoring and evaluating safety and quality of care within the health care system. Therefore, research on clinical indicators can improve the quality of care, promote good practices, clarify key concepts, and identify gaps vital to nursing care.

Objective:
The study aims to explore nurse-sensitive indicators to find significant research areas and prioritize them.

Design:
The study design is exploratory research conducted through scoping review, followed by Delphi consultation to identify nurse-sensitive indicators applicable in the Saudi Arabia health care system and prioritize these indicators as research areas.

Results:
The most frequently cited indicators are patient fall, medication error, patient satisfaction, catheter-associated infection, pain, pressure ulcer, the incidence of deep vein thrombosis or pulmonary embolism, appropriate levels of nursing skill mix, and nursing initial and need assessment. The result shows that (33) NSIs are essential to the quality of nursing care and patient safety in Saudi Arabia.

Conclusion:
Patient-centeredness, patient safety, a healthy work environment, and a nursing informatics system are significant research dimensions. We found that nurse satisfaction, patient satisfaction, pressure ulcers, patient falls, nurse-patient communication, patient engagement, and pain management are research priorities.

Recommendations:
Further studies must be conducted on NSIs that address patient-centeredness, safety, a healthy work environment, and a nursing informatics system. It can be observed that most of the studies focused on outcome indicators, and there is a need to study patient-reported indicators as a significant patient-centered concept.
The Cytoglobin Expression Under Hypoxic Conditions in Covid-19 Cases
Authors: Wulandari Endah , Hapsari Rr Ayu Fitri , Tjakradidjaja Francisca A , Alfiah   , Suri Auliyani Andam 
Published: May 2023

Introduction:
Cytoglobin (Cygb) is an oxygen transporter marker that appears in hypoxic conditions. The clinical condition of Corona Virus Disease 2019 (COVID-19) cases, in general is that patients experience hypoxemia with low oxygen saturation. The Cygb gene is stimulated by the Hypoxia-Inducible Factor-1alpha (HIF-1α) transcription factor, which is stable in hypoxia.

Methods:
This study investigates Cygb expression in hypoxic COVID-19 cases. The design of this research is analytically observational. Parameters measured were Cygb mRNA and protein levels, correlation of HIF-1α and Cygb proteins in COVID-19 patients with Alpha, Beta, Delta, Omicron variants and negative control patients.

Results:
The results showed that each Cygb mRNA level decreased by 0.50, 0.92, 0.75 and 0.84 times that of the control. In contrast, Cygb protein levels (ng/mL) increased (16.95; 20.33; 21.20; 14.01 and 6.29 control). Strong negative correlation between mRNA and Cygb protein (R = -0.611). Strong positive correlation between HIF-1α and Cygb protein (R = 0.670).

Conclusion:
This study showed that Cygb mRNA expression decreased, further increasing Cygb protein; HIF-1α protein levels increased, further increasing Cygb protein. In COVID-19 patients (Alpha, Beta, Delta and Omicron variants), there is an increase in Cygb protein levels through stimulation of HIF-1α, which is stable under hypoxic conditions. The regulation of Cygb in this study has the potential to become the basis for handling cases of viral infections or other cases of hypoxia.
<strong>Trends in Time in Range–Related Publications and Clinical Trials: A Bibliometric Review</strong>
Authors: M. Patel Pranav , M. Abaniel Richard , Dogra Natasha , B. Lo Charles , A. Frazzitta Marie , S. Virdi Naunihal 
Published: May 2023

<p> </p>
<p><strong>Objective. </strong>The goal of this article was to describe trends in publications (including conference abstracts) and clinical trials that report on glycemic time in range (TIR).</p>
<p><strong>Data sources.</strong> Reviewed databases included but were not limited to MEDLINE and Embase. Clinical trial registries were also sourced. </p>
<p><strong>Study selection.</strong> All studies reporting TIR published between 2010 and 2021 were included. Clinical trials reporting TIR that started in or after 2010 were also included. Non-English publications, abstracts, and clinical trials were excluded. Book chapters, nonhuman studies, and studies not reporting TIR were excluded.</p>
<p><strong>Data extraction. </strong>Manuscript/abstract category, publication year, study region, interventional versus observational role of continuous glucose monitoring (CGM), and clinical trial start and completion dates were captured. Glycemic outcomes reported in publications or trials, including TIR as a primary outcome, A1C, time below range (TBR), and time above range (TAR), were also captured. </p>
<p><strong>Results. </strong>A total of 373 clinical trials, 531 publications, and 620 abstracts were included in the review. The number of trials, publications, and abstracts reporting TIR significantly increased, particularly between 2018 and 2021, during which time the number of clinical trials, publications, and conference abstracts reporting TIR increased by sixfold, 12-fold, and 4.5-fold, respectively. About 35–44% of studies reported TIR as a primary outcome. Approximately 54% of clinical trials, 47% of publications, and 47% of conference abstracts reported the role of CGM to be observational. TBR was reported more often than TAR.</p>
<p><strong>Conclusion. </strong>The marked increase in the number of trials, publications, and abstracts reporting TIR highlights the increasing significance and acceptance of TIR as an outcome measure in diabetes management. </p>
Rendahnya Minat Belajar Siswa pada Masa Covid-19: Kajian Aksiologi
Authors: Hartati Leni , Jimmy Copriadi  
Published: May 2023

AbstrakPembelajaran antara pendidik dan peserta didik harus dilakukan di lingkungan sekolah. Karena merupakan tempat pertemuan yang ideal antara pendidik dan peserta didik untuk mencapai pendidikan yang berkualitas. Pendidikan mengandung nilai-nilai etika, moral, estetika, dan sosial untuk mencapai keberhasilan pendidikan. Namun hal itu berubah ketika aktivitas belajar mulai terjadi secara online di rumah. Semua pihak mulai menyesuaikan diri yang berbeda menjadi sangat sulit. Sekolah dan pendidik harus bekerja keras untuk menemukan internet yang sesuai sebagai media pembelajaran. Siswa dan orang tua di rumah berjuang untuk mengikuti pembelajaran online. Setelah pelaksanaannya, ternyata banyak kendala yang dihadapi oleh para pihak. Kasus yang menjadi perhatian besar adalah menurunnya minat belajar anak. Dalam penelitian ini, penulis menggunakan metode kualitatif untuk menggambarkan permasalahan yang muncul. Hasil pendataan yang dilakukan, diketahui bahwa menurunnya minat belajar anak dan kurangnya belajar, yang memotivasi anak untuk semangat dalam belajar. Tujuan dari penelitian ini adalah untuk mengimplementasikan nilai-nilai etika, dukungan sosial dalam kehidupan bermasyarakat. Disimpulkan bahwa; penurunan minat belajar anak (malas) dari kajian aksiologi nilai dan perilaku buruk tidak boleh diterima dengan alasan apapun.Kata Kunci: Minat Belajar, Belajar Biologi, AksiologiAbstract Learning between educators and students must be carried out in the school environment. Because it is an ideal meeting place between educators and students to achieve quality education. Education contains ethical, moral, aesthetic, and social values to achieve educational success. But that changed when learning activities started happening online at home. All parties begin to adjust the different becomes very difficult. Schools and educators must work hard to find the appropriate Internet as a learning medium. Students and parents at home struggle to keep up with online learning. After its implementation, it turned out that there were many obstacles faced by the parties. Cases that are of great interest are children's declining interest in learning. In this study, the authors use qualitative methods to describe the problems that arise. The results of data collection carried out, it is known that the decline in children's interest in learning and lack of learning, which motivates children to be enthusiastic in learning. The purpose of this research is to implement ethical values, social support in social life. It was concluded that; a decrease in children's interest in learning (lazy) from axiological studies of values and bad behavior should not be accepted for any reason.
PERBEDAAN POLA PIKIR AL-KINDI DAN ARISTOTELES DALAM MEMAHAMI HAKIKAT TUHAN
Authors: Muhammad Yusron Maulana El-Yunusi  , Bryna Azarine Rozyan  
Published: May 2023

Logika dan Ilmu adalah dua hal yang tidak bisa dilepaskan. Keduanya akan terus bekerja dan menghasilkan sebuah karya-karya yang bermanfaat. Aristoteles dan al-Kindi salah satunya. Dua orang yang berhasil memberikan pemahaman dari ilmu filsafat. Aristoteles berasal dari yunani dan al-kindi berasal dari islam. walaupun terdapat perbedaan zaman dan cara berpikir, namun al-kindi tetap menghormati filosof sebelumnya. Belajar akan sebuah karya adalah hal yang disukai dan diminati oleh keduanya. Inspirasi dalam mengambil sebuah pemikiran juga mengalami perbedaan yang sama. Aristoteles mengambil dari gurunya yakni plato, sedangkan al-kindi mempelajari karya Aristoteles untuk disambung dengan pemikirannya sekaligus diperbarui dengan bumbu keislaman tanpa mengubah artian aslinya. Adapun keahlian dari keduanya sangat baik dalam hal mengajar dan memberikan ilmunya kepada para pencari ilmu. Hubungan guru dan murid merupakan sebuah hubungan yang sulit diputus dan dipisahkan dikarenakan indahnya kenangan pembelajaran hidup. Kepercayaan dan penghianatan adalah dua hal yang memang ada sejak dahulu hingga sekarang.
Kata Kunci: Tuhan, Perbedaan, Eksitensi, Emanasi
Proses Diagnosis dalam Konseling: Konsep dan Menganalisa sebagai Konselor Profesional dalam Problem Solving Klien
Authors: Nurhafiza Nurhafiza , Karneli Yeni , Hariko Rezki , Hasgimianti Hasgimianti 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui proses diagnosis dalam konseling sebagai konselor professional dalam Problem Solving Klien. Metode penelitian ini adalah kualitatif dengan pendekatan studi pustaka (library research), kegiatan mempelajari, mendalami dan mengutip teori-teori atau konsep-konsep dari sejumlah literatur yang digunakan berasal dari buku, jurnal, atau karya tulsi lainnya yang secara relevan atau valid dengan topik yang digunakan, fokus atau variabel penelitian. Hasil dari penelitian ini menujukkan bahwa berbagai masalah yang dihadapi klien saat ini konselor dapat menggunakan berbagai tahap diagnosis untuk mengentaskan maslaah klien. Bahwasannya diagnosis suatu langkah awal untuk mengikuti analisis data, konselor memilih dari berbagai kumpulan kasus, fakta-fakta yang relevan sehingga membentuk dasar prognosis dan rencana untuk konseling atau psikoterapi selanjutnyaKata Kunci : Diagnosis, Konselor Professional, Problem Solving Klien TRANSLATE with x EnglishArabicHebrewPolishBulgarianHindiPortugueseCatalanHmong DawRomanianChinese SimplifiedHungarianRussianChinese TraditionalIndonesianSlovakCzechItalianSlovenianDanishJapaneseSpanishDutchKlingonSwedishEnglishKoreanThaiEstonianLatvianTurkishFinnishLithuanianUkrainianFrenchMalayUrduGermanMalteseVietnameseGreekNorwegianWelshHaitian CreolePersian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster PortalBack//