bluuebunny/crossref_metadata_2025_split huggingface dataset:
A lecture on sleep health improves sleep knowledge and beliefs in physical therapy students
Authors: Siengsukon Catherine F. , Glaser Allison , Nelson Eryen 
Published: August 2023

Abstract
Background: Challenges to integrating health promotion (including sleep health) into entry-level physical therapist curricula include lack of faculty expertise, time, and support. A lecture provided by a content expert may mitigate the challenges. The purpose of this study was to determine if a remotely provided sleep education session impacts Doctor of Physical Therapy students’ knowledge and beliefs about sleep.
Methods: Faculty shared the opportunity to participate in the study 1-3 days prior to the lecture. The survey included demographics, a sleep health knowledge question, 11 questions on “What I think about sleep as a professional”, and the 20-item Sleep Beliefs Scale. McNemar’s and paired sample t-tests determined change in knowledge and beliefs.
Results: 209 individuals (70% female, 86% Caucasian, 25.5 ± 3.4 years old) completed the pre-lecture survey, and 137 individuals completed the post-lecture survey. There was a significant increase in knowledge about sleep health (p < .001) and Sleep Beliefs Scales score (p < .001).
Conclusions: This is study demonstrated that a single remotely provided sleep education session increased DPT students’ knowledge and changed their beliefs about sleep. Future studies should determine if these positive beliefs about sleep translate into clinical practice and enhance patient outcomes.
Anodal transcranial direct current stimulation associated with aerobic exercise on the functional and physical capacity of patients with heart failure with reduced ejection fraction: ELETRIC study protocol.
Authors: Silva Vanessa Christina Costa da , Arêas Fernando Zanela da Silva , Lopes Antonio Luiz Ribeiro Boechat , Val Fernando Almeida , Costa Allyson Guimarães da , Santos Joana Colares Correa dos , Ferreira João Marcos Bemfica Barbosa , Arêas Guilherme Peixoto Tinoco 
Published: August 2023

Abstract
Background
The hallmark symptom of heart failure (HF) is severe exercise intolerance. Fortunately, accumulated evidence suggests that exercise programs improve physical performance, enhance autonomy in daily activities and quality of life, and reduce cardiovascular and other hospitalizations. Recently, experimental studies have explored the application of non-invasive brain stimulation techniques, especially transcranial direct current stimulation (tDCS), aiming to improve physical performance due to its ability to modulate brain functioning. The primary objective of the present study is to evaluate the effects of anodal tDCS associated with aerobic exercise on the functional capacity of patients with HF with reduced ejection fraction (HFrEF). Secondary objectives are to compare the effects of tDCS associated with aerobic exercise vs. sham-tDCS associated with aerobic exercise on cardiopulmonary exercise capacity; inflammatory cytokines; and quality of life.
Methods
This is a two-arm, prospectively registered, randomized trial with concealed allocation, double-blind, and intention-to-treat analysis. Forty-four patients with HFrEF will be recruited. The experimental group will undertake 25–30 min aerobic exercise training associated with tDCS, for 4 weeks. The control group will undergo the same aerobic exercise training, but with sham-tDCS. The primary outcome will be functional performance by the six-minute walk test. Secondary outcomes will include cardiopulmonary exercise capacity, inflammatory cytokines, and quality of life. Outcomes will be collected by a researcher blinded to group allocation at baseline (T0), and after four weeks of intervention (T1).
Discussion
Although previous studies have investigated the combined effect of tDCS on T3 area and physical performance and have suggested that tDCS could have reduced ratings of perceived exertion by affecting the activity of the insular cortex, and therefore increase exercise tolerance, this study is the first to evaluate the effects of the addition of anodal tDCS to aerobic exercise training for improving physical and functional performance, decreasing the perceived exertion, altering the quantification of inflammatory cytokines, and improving the subclinical values of the cardiopulmonary test in patients with HFrEF, which could result in an important advance in cardiac rehabilitation for patients with chronic HF.
Trial registration
Brazilian Registry of Clinical Trials (ReBEC) RBR-10w787j6. Registered 25 April, 2023, https://ensaiosclinicos.gov.br/pesquisador
Acute Post-Operative Pain Management: Practice Patterns and Treatment Challenges
Authors: Gasoma ElMuhtadi B. Y. , Mohammed Leenah M. S. 
Published: August 2023

Abstract
Background
Currently, surgical practice is thought to include postoperative pain management as a necessary component. Nevertheless, a lot of patients experience significant pain after surgery. The objective of the current survey was to evaluate the status of postoperative pain relief and to assess the types and routes of drugs administered for this purpose
Method
A questionnaire form was used to collect demographic data, type of surgery, anesthesia, and patient satisfaction. Assessment of pain severity was done during the interview using one of the following pain scales: verbal, numerical and visual. This was done 4 and 8 hours after surgery. Before leaving the hospital, patients who were discharged the same day as surgery underwent a single face-to-face interview.
Results
Of 258 patients, 34.3% experienced moderate to severe pain postoperatively at rest and 31.5 % on movement. No analgesics were prescribed to 7.1 % of the patients and of the remainder, a single analgesic was prescribed to 52.8%. Thyroid & minor abdominal surgery patients had the lowest pain intensity, especially in comparison to those undergoing thoracic and major abdominal surgery. Paracetamol and Diclofenac were the drugs most commonly prescribed (to 98.6 % and 41.4 % of patients respectively), most often on a regular schedule rather than on-demand.
Conclusion
Despite concerns, in some patient groups, analgesic usage may not be sufficient. However, our study indicates new factors that influence the severity of pain, such as analgesic drugs, anesthetic technique, and type of surgery. Awareness among professionals and the public is needed and a structured pain management program is crucial.
Robotic versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT: the RELIANT pragmatic randomized trial.
Authors: Paez Rafael , Lentz Robert J , Salmon Cristina , Siemann Justin K , Low See-Wei , Casey Jonathan D , Chen Heidi , Chen Sheau-Chiann , Avasarala Sameer , Shojaee Samira , Rickman Otis B , Lindsell Christopher J , Gatto Cheryl L , Rice Todd W , Maldonado Fabien 
Published: August 2023

Abstract
• Background: Robotic assisted bronchoscopy has recently emerged as an alternative to electromagnetic navigational bronchoscopy for the evaluation of peripheral pulmonary lesions. While robotic assisted bronchoscopy is proposed to have several advantages, such as an easier learning curve, it is unclear if it has comparable diagnostic utility as electromagnetic navigational bronchoscopy.
• Methods: Robotic versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT (RELIANT) is an investigator-initiated, single-center, open label, noninferiority, cluster randomized controlled trial conducted in two operating rooms at Vanderbilt University Medical Center. Each operating room is assigned to either robotic assisted or electromagnetic navigational bronchoscopy each morning, with each OR day considered one cluster. All patients undergoing diagnostic bronchoscopy for evaluation of a peripheral pulmonary lesion in one of the two operating rooms are eligible. Schedulers, patients and proceduralists are blinded to daily group allocations until randomization is revealed for each operating room each morning. The primary endpoint is the diagnostic yield defined as the proportion of cases yielding lesional tissue. Secondary and safety endpoints include procedure duration and procedural complications. Enrolment began on March 6, 2023, and will continue until 202 clusters have been accrued, with expected enrolment of approximately 400 patients by the time of completion in March of 2024.
• Discussion: RELIANT is a pragmatic randomized controlled trial that will compare the diagnostic yield of the two most commonly used bronchoscopic approaches for sampling peripheral pulmonary lesions. This will be the first known cluster randomized pragmatic trial in the interventional pulmonology field and the first randomized controlled trial of robotic assisted bronchoscopy.
• Trial registration: ClinicalTrials.gov registration (NCT05705544) on January 30, 2023.
Associations between school-based fluoride mouth-rinse program, medical-dental expense subsidy policy, and children's oral health in Japan: an ecological study
Authors: Yamamoto Takafumi , Kiuchi Sakura , Ishimaru Miho , Fukuda Hideki , Yokoyama Tetsuji 
Published: August 2023

Abstract

Background
Dental caries are a common non-communicable disease among children. As a public health measure at the prefectural level, school-based fluoride mouth-rinse (S-FMR) programs and medical/dental expense subsidy policies may reduce the incidence of dental caries and tooth loss. Prefectures focusing on promoting oral health policies may promote both, but the interaction effect of implementing both subsidy policies and S-FMR at the prefectural level on caries prevention has not yet been examined.
Methods
We conducted an ecological study using cross-sectional, prefecture-level aggregated data in Japan. Standardized beta (B) and 95% confidence intervals (CI) were calculated for the dependent variables for oral health using linear regression analyses adjusted for possible confounders such as dentist density and prefectural socioeconomic circumstances. Three dependent variables were used; the standardized claim ratio (SCR) of deciduous tooth extraction, the SCR of dental sealants, and 12-year-olds’ decayed, missing, or filled permanent teeth (DMFT). The independent variables were S-FMR and subsidy policy in three models: co-payment until children enter elementary school (n=23), no co-payment until children enter elementary school (n=7), and co-payment continuing beyond elementary school (n=17). Interaction terms were multiplied by the S-FMR and subsidy policy and entered into each model.
Results
S-FMR was not associated with the SCR of deciduous tooth extractions and dental sealants. High S-FMR utilization was associated with low DMFT (B = -0.26, 95% CI -0.46; -0.06). No co-payment until children enter elementary school was positively associated with the SCR of deciduous tooth extraction compared to co-payment until children enter elementary school (B = 0.37, 95% CI 0.05; 0.69). The subsidy policy was not associated with the SCR of dental sealants and DMFT. No interaction was found between S-FMR and the subsidy policy at all outcomes.
Conclusion
S-FMR, one of the universal approaches, was an effective strategy for maintaining oral health among children, and this association was independent of the subsidy policy on oral health.
Evaluation of ChatGPT’s responses to information needs and information seeking of dementia patients
Authors: Saeidnia Hamid Reza , Kozak Marcin , Lund Brady D. , Hassanzadeh Mohammad 
Published: August 2023

Abstract

Background: Many people in the advanced stages of dementia require full-time caregivers, most of whom are family members who provide informal (non-specialized) care. It is important to provide these caregivers with high-quality information to help them understand and manage the symptoms and behaviors of dementia patients. This study aims to investigate the evaluation of ChatGPT, a chatbot built using the GPT large language model,in responding to information needs and information seeking of such informal caregivers.
Methods: We identified the information needs of dementia patients based on the relevant literature (22 articles were selected from 2442 retrieved articles). From this analysis, we created a list of 31 items that describe these information needs, and used them to formulate relevant 118 questions. We then asked these questions to ChatGPT and investigated its responses. In the next phase, we asked 15 informal and 15 formal dementia-patient caregivers to analyze and evaluate these ChatGPT responses, using both quantitative (questionnaire) and qualitative (interview) approaches.
Findings: In the interviews conducted, informal caregivers were more positive towards the use of ChatGPT to obtain non-specialized information about dementia compared to formal caregivers. However, ChatGPT struggled to provide satisfactory responses to more specialized (clinical) inquiries. In the questionnaire study, informal caregivers gave higher ratings to ChatGPT's responsiveness on the 31 items describing information needs, giving an overall mean score of 3.77 (SD 0.98) out of 5; the mean score among formal caregivers was 3.13 (SD 0.65), indicating that formal caregivers showed less trust to ChatGPT's responses compared to informal caregivers.
Conclusion: ChatGPT’s responses to non-clinical information needs related to dementia patients were generally satisfactory at this stage. As this tool is still under heavy development, it holds promise for providing even higher-quality information in response to information needs, particularly when developed in collaboration with healthcare professionals. Thus, large language models such as ChatGPT can serve as valuable sources of information for informal caregivers, although they may not fully meet the needs of formal caregivers who seek specialized (clinical) answers. Nevertheless, even in its current state, ChatGPT was able to provide responses to some of the clinical questions related to dementia that were asked.
Lures change the detectability of feral cats on the arid landscape
Authors: Lohr Cheryl , Nilsson Kristen , Johnson Ashleigh , Hamilton Neil , Onus Mike , Algar Dave 
Published: August 2023

Abstract
Feral cats (Felis catus) are difficult to manage and harder to detect. For 20 years, we have been using an annual aerial baiting program to suppress feral cat numbers on the Matuwa National Park in Western Australia. The efficacy of this management is monitored via pre-bait and post-bait surveys of feral cat activity on sandy tracks, and at least 120 camera-traps. In 2021, we detected cats on only five occasions, despite using 130 camera-traps with an olfactory lure known as Catastrophic. In this study, we measured the detectability of feral cats at three camera-traps arrangements on Matuwa: passive cameras (n = 57), camera with the Catastrophic lure (n = 120), and cameras with a Magnum Scrape-Dripper ® (n = 63) dispersing cat urine. All 120 sites had two cameras, one with Catastrophic for comparison with data from prior surveys, plus a camera that was either passive or had a dripper. Camera-traps were active for an average of 57 days (range 55–60 days). Cats were detected by cameras with drippers 29 times more than passive cameras and six times more than Catastrophic cameras. Further, cats spent on average 2.6 seconds in front of passive cameras, 8.5 seconds in front of Catastrophic cameras, and 65.5 seconds in front of drippers. The ability to detect feral cats affects the magnitude and accuracy of abundance or occupancy estimates for cats. Therefore, our research highlights a severe weakness in current feral cat survey methodologies and any management decisions derived from that data.
Effects of Global Brand Value on Consumer’s Preference: Mediating Role of Brand Advertisement
Authors: Oh Doo Hwan , Shin Gyu Ha 
Published: August 2023

Abstract
This study examined the mediating effect of international brand advertisement between the corporate global brand value and preference of consumers by using the cause marketing strategy. To examine the proposed model, a questionnaire survey was developed to collect data from 315 male and female consumers who lived in Seoul and Gyeonggi area of Republic of Korea. Finally, 276 datas were used except 39 copies that were unfaithfully answered. The SPSS 21.0 and AMOS 22.0 program are used to analyze the collected data and proved the reason “Why do Consumers focus on global brand marketing?” The results of this study showed that consumers’ perception of the relevance and sustainability of corporate global brand value indicated a high correlation with corporate international brand advertisement. This proved the hierarchical structure of the value-attitude-behavior model (Homer & Kahle, 1988) emphasizing the mediating role of purchasing attitude between consumers’ purchasing value and purchasing decision behavior. Therefore, this study implies that international brand advertisement as a parameter proved to be an important brand relativity factor that regulates brand preference between consumers’ brand value judgment and brand selection.
Biallelic NEXN variants and fetal onset dilated cardiomyopathy: two independent case reports and revision of literature.
Authors: PICCIOLLI IRENE , Ratti Angelo , Rinaldi Berardo , Baban Anwar , Iascone Maria , Francescato Gaia , Cappelleri Alessia , Magliozzi Monia , Novelli Antonio , Parlapiano Giovanni , Colli Anna Maria , Persico Nicola , Carugo Stefano , Mosca Fabio , Bedeschi Maria Francesca 
Published: August 2023

Abstract

Background Dilated cardiomyopathy (DCM) is etiologically heterogeneous. With the rapid evolution in laboratory investigations, genetic background is increasingly determined including many genes with variable penetrance and expressivity. Biallelic NEXN variants are rare in humans and associated with poor prognosis: fetal and perinatal death or severe DCMs in infants.Case presentation: We describe two male infants with prenatal diagnosis of dilated cardiomyopathy with impaired ventricular contractility. One of the patients showed hydrops and polyhydramnios. Postnatally, a DCM with severely reduced systolic function was confirmed and required medical treatment. In patient 1, Whole Exome Sequencing (WES) revealed a homozygous NEXN variant: c.1156dup (p.Met386fs) while in patient 2 a custom Next Generation Sequencing (NGS) panel revealed the homozygous NEXN variant c.1579_1584del (Glu527_Glu528del). These NEXN variants have not been previously described. Unlike the unfavorable prognosis described for biallelic NEXN variants, we observed in both our patients a favorable clinical course over time.Conclusion This report might help to broaden the present knowledge regarding NEXN biallelic variants and their clinical expression in humans. It might be worthy to consider the inclusion of the NEXN gene sequencing in the investigation of pediatric patients with DCM.
The efficacy of Tephrosia vogelii and Azadirachta indica leaf extract combinations against fall Armyworm, Spodoptera frugiperda, in Maize.
Authors: Nemeyimana James , Muhooozi Rashid S , Nuwagira Upton , Ssenkuba Francis 
Published: August 2023

Abstract
Spodoptera frugiperda is an economical pest affecting Uganda’s agriculture. These pests are voracious feeders, polyphagous in nature and mostly affect the cereal crops such as maize and wheat which is the staple food of Africa and Uganda in particular, thus pause a threat to Africa’s food security. Ugandan farmers largely depend on synthetic pesticide to control FAW, however these have negative impacts on the environment such as water pollution, death of beneficial organisms such as bees, and development of pesticide resistance, and are toxic to human beings and the aquatic life. The aim of this study was to evaluate the bioactivity of Tephrosia vogelii and Azadirachta indica leaf extracts as botanicals against Spodoptera frugiperda under laboratory conditions. The selected botanicals were subjected to phytochemical screening to examine presence of pesticide phytochemical groups of namely; flavonoids, saponnins, terpenoids, alkaloids, tannins and glycosides as highlighted by different literature Fourth instar larvae were collected from established fields in south western Uganda where there was no application of pesticides before and then n transferred to the biology laboratory of Mbarara University of Science and Technology under the faculty of science where they were reared to obtain enough study populations(second instar generation). Aqueous plant extracts were applied in varying combinations as treatments, the percentage mortality rates were recorded at 12 hours interval for 48 hours after treatment. Sterile tap water and cypermethrin were used as negative and positive controls respectively. The tested treatments of the botanicals were mixed in a combination of T.vogelii & A. indica powder extract weight per volume respectively, where treatment A(20g:10g), B(10g:20g), C(15g:15g), D(30g T.vogelii only) & E(30g A. indica only) and a positive control of cypermethrin. Results showed that treatments A, D and the positive control had a higher percentage mortality (> 50%, p > 0.05) after 48hours of application compared to treatments B, C and E that had a lower percentage mortality below (< 50%, p < 0.05). The botanical treatments that showed higher mortality percentage against FAW larvae contained more of the T.vogelii extract, this can be used as an extract in most of the botanicals against the FAW larvae. As an alternative, smallholder farmers can include botanicals in their integrated pest management systems around Uganda and East Africa at large conditions in Ethiopia and elsewhere in Africa.
International comparison of Qualification Process for Medical Product Development Tools
Authors: Uchijima Daichi , Kano Shingo 
Published: August 2023

Abstract
Introduction
The qualification of medical product evaluation tools is underway in the United States, Europe, and Japan to reflect advancements in the basic science of medical products. In Europe and the U.S., Guidance of Guidances (GoG) policies that clarify regulators’processes, tasks, and methods of sponsor involvement are adopted to issue tool guidance. However, in Japan, a non-GoG type policy focusing on supporting the research and development for tools without defining a tool guidance-making process has been adopted.
Methods
In this study, an analytical framework for the life cycle of development tools was constructed, including pre- and post-tool qualification processes, to compare the above-mentioned two approaches. For this study, cases in Japan were selected as experimental cases, with Western cases serving as controls. The progress of tool qualification and composition of deliverables were analyzed.
Results and Conclusions
It was indicated that in the GoG type policy, where processes are defined and involvement methods are clarified, tool qualification can progress more smoothly than in a non-GoG type policy. The policy further shows that deliverables may have a consistent composition. In contrast, GoG type policies alone present challenges in connecting upstream tools for R&D support.