bluuebunny/crossref_metadata_2025_split huggingface dataset:
Colour and Composition in the Work of Jean Follain
Authors: Shinabargar Scott 
Published: March 2023

Abstract

This study calls into question the frequent identification of Jean Follain as a ‘miniaturiste’, demonstrating how this poet in fact utilizes elements of pictorial representation in a much more ambitious and nuanced manner than such a label would suggest. Identifying remarkably frequent appearances of colour throughout two of his best-known collections,
Exister
and
Territoires
, we discover that such details are not merely minor descriptive terms among others, but key factors in the distinct impression produced by the texts in question. As the analysis progresses from paler to more vivid hues, we will observe that, in addition to bringing into play traditional connotations (white/purity, red/violence), the poet deploys colour in decidedly painterly ways — actually organizing and dynamizing the visualized space of the text through very deliberate placement, orienting and drawing the reader in. Such techniques become particularly interesting when considering Follain’s application of multiple colours, whereby he would seem to be attempting to reproduce the most physical phenomena in colour perception, through the interaction of specific hues. However successful these ‘translations’ from visual art are, a primary objective is surely realized: the reader straining to see actively, as Follain did.
Genomic and cytogenetic analysis of the Ceratitis capitata temperature-sensitive lethal region
Authors: Sollazzo Germano , Gouvi Georgia , Nikolouli Katerina , Aumann Roswitha A , Djambazian Haig , Whitehead Mark A , Berube Pierre , Chen Shu-Huang , Tsiamis George , Darby Alistair C , Ragoussis Jiannis , Schetelig Marc F , Bourtzis Kostas 
Published: March 2023

Abstract
Genetic sexing strains (GSS) are an important tool in support of sterile insect technique (SIT) applications against insect pests and disease vectors. The yet unknown temperature-sensitive lethal (tsl) gene and the recently identified white pupae (wp) gene have been used as selectable markers in the most successful GSS developed so far, the Ceratitis capitata (medfly) VIENNA 8 GSS. The molecular identification of the tsl gene may open the way for its use as a marker for the development of GSS in other insect pests and disease vectors of SIT importance. Prior studies have already shown that the tsl gene is located on the right arm of chromosome 5, between the wp and Zw loci (tsl genomic region). In the present study, we used genomic, transcriptomic, bioinformatic, and cytogenetic approaches to characterize and analyze this genomic region in wild-type and tsl mutant medfly strains. Our results suggested the presence of 561 genes, with 322 of them carrying SNPs and/or insertion–deletion (indel) mutations in the tsl genomic region. Furthermore, comparative transcriptomic analysis indicated the presence of 32 differentially expressed genes, and bioinformatic analysis revealed the presence of 33 orthologs with a described heat-sensitive phenotype of Drosophila melanogaster in this region. These data can be used in functional genetic studies to identify the tsl gene(s) and the causal mutation(s) responsible for the temperature-sensitive lethal phenotype in medfly, and potentially additional genes causing a similar phenotype.
Does Incident Cardiovascular Disease Lead to Greater Odds of Functional and Cognitive Impairment? Insights From the Health and Retirement Study
Authors: Stone Katherine L , Zhong Judy , Lyu Chen , Chodosh Joshua , Blachman Nina L , Dodson John A 
Published: March 2023

Abstract

Background
Although studies to date have broadly shown that cardiovascular disease (CVD) increases cognitive and physical impairment risk, there is still limited understanding of the magnitude of this risk among relevant CVD subtypes or age cohorts.

Methods
We analyzed longitudinal data from 16 679 U.S. Health and Retirement Study participants who were aged ≥65 years at study entry. Primary endpoints were physical impairment (activities of daily living impairment) or cognitive impairment (Langa–Weir Classification of dementia). We compared these endpoints among participants who developed incident CVD versus those who were CVD free, both in the short term (&lt;2-year postdiagnosis) and long term (&gt;5 years), controlling for sociodemographic and health characteristics. We then analyzed the effects by CVD subtype (atrial fibrillation, congestive heart failure, ischemic heart disease, and stroke) and age-at-diagnosis (65–74, 75–84, and ≥85).

Results
Over a median follow-up of 10 years, 8 750 participants (52%) developed incident CVD. Incident CVD was associated with significantly higher adjusted odds (aOR) of short-term and long-term physical and cognitive impairment. The oldest (≥85) age-at-diagnosis subgroup had the highest risk of short-term physical (aOR 3.01, 95% confidence interval [CI]: 2.40–3.77) and cognitive impairment (aOR 1.96, 95% CI: 1.55–2.48), as well as long-term impairment. All CVD subtypes were associated with higher odds of physical and cognitive impairment, with the highest risk for patients with incident stroke.

Conclusions
Incident CVD was associated with an increased risk of physical and cognitive impairment across CVD subtypes. Impairment risk after CVD was highest among the oldest patients (≥85 years) who should therefore remain a target for prevention efforts.
Person–Environment Exchange Processes in Transition into Dementia: A Scoping Review
Authors: Niedoba Simone , Oswald Frank 
Published: March 2023

AbstractBackground and ObjectivesThe important role that the environment plays in the lives of older people is widely acknowledged. To date, little is known about person–environment processes during the early stages of dementia. This scoping review aims to provide an overview of the processes involved during early dementia and the relationship to different dimensions of their life space.Research Design and MethodsA scoping review was conducted according to the Johanna Briggs Institute Manual, which involved searching for research on early dementia and the environment across 3 databases.ResultsA total of 1,358 records were screened, with 284 sources included in the first categorization of the diverse relationships that exist between the environment and the person living with early dementia. Finally, 102 sources were selected that describe person–environment exchange processes of agency, belonging, or stress. People living with dementia actively shape, use, seek out, and avoid their environment as a reaction to both declining abilities and environmental barriers. Specifically, feelings of connectedness and familiarity are important.Discussion and ImplicationsTaking both an environmental gerontology perspective and a processual, that is, transition perspective broadens the understanding of the experience and behavior of people living with early dementia. They constantly interact with and shape their environment and desire a sense of belonging. This sense of belonging might be threatened by dementia but can be actively reinforced by people living with dementia. These person–environment processes and their dynamics over time should be further investigated. Especially, quantitative data and data on socioeconomic environments are lacking.
When to conduct, and when not to conduct, management strategy evaluations
Authors: Walter III J F , Peterson C D , Marshall K , Deroba J J , Gaichas S , Williams B C , Stohs S , Tommasi D , Ahrens R 
Published: March 2023

Abstract
The basis of natural resource management is decision making under uncertainty while balancing competing objectives. Within fisheries management, a process described as management strategy evaluation (MSE) is becoming increasingly requested globally to develop and test management procedures. In a fisheries or other natural resource context, a management procedure is a rule that predetermines the management response given feedback from the resource and is simulation tested to be robust to multiple uncertainties. MSEs are distinguished from other risk or simulation analyses by the explicit testing of the feedback mechanism that applies decision rule-based management advice back to the simulated population or ecosystem. Stakeholder input is frequently cited as a best practice in the MSE process, since it fosters communication and facilitates buy-in to the process. Nevertheless, due to the substantial additional cost, time requirement, and necessary scientific personnel, full stakeholder MSEs remain relatively uncommon. With this communication, we provide guidance on what constitutes an MSE, when MSEs should be undertaken or where simpler approaches may suffice, and how to prioritize the degree of stakeholder participation.
How Worried Should We Be? The Implications of Fabricated Survey Data for Political Science
Authors: Castorena Oscar , Cohen Mollie J , Lupu Noam , Zechmeister Elizabeth J 
Published: March 2023

Abstract
Surveys are ubiquitous in the study of politics, making enumerator fabrication a critical issue. A prevailing view is that faked interviews affect inferences drawn from compromised datasets. Researchers have generated theories about how fabrication might affect inferences. Yet, speculation has outpaced systematic testing. We leverage a rare dataset to address this gap: a national face-to-face survey in Venezuela in which a uniquely high volume of falsified interviews was detected, canceled, and replaced. Comparing the verified and fraudulent datasets, we find that descriptive inference is sometimes affected, but correlational results hold, even in a dataset with an unusually high-fabrication rate. Enumerators largely fabricate plausible data. Though still egregious, enumerator fabrication may not constitute a grave threat to political science research.
Making Experts of Ourselves: Laura Puffer Morgan, Pacifism, and the Logics of the Security Sector
Authors: Turkington Rebecca 
Published: March 2023

AbstractFor more than a century, gendered divisions between “insider” experts and “outsider” activists kept women at the margins of arms control policy, despite their long-standing disarmament advocacy. In the interwar period, when opportunities for women to influence security thinking from the inside were essentially nonexistent, lobbyist and analyst Laura Puffer Morgan educated herself in the technical knowledge of weaponry, the economics of military spending, and the bureaucratic processes that governed both. Unlike many of her colleagues in the broader peace movement, Puffer Morgan was “equipped to ‘talk army’ with generals or analyze tonnages with admirals.” She believed that women could and should become security experts who would “meet the militarists on their own ground”—a goal she advanced in her own career through voluminous written analysis and through public education about the concrete details of arms reduction. By turning to technical expertise over moral appeal, she was able to act as an advisor to civil society coalitions and delegates alike during the disarmament conferences of the 1920s and 1930s, and advance a peace agenda in quarters where many of her peers were seen as radical interlopers. She was one of a small group of women able to claim the mantle of “expert” and her career illustrates an alternative way women participated in disarmament thinking.
Effect of ethanol preservation on prosomal length of the calanoid copepodParvocalanus crassirostris(Dahl, 1894)
Authors: La Rosa-Izquierdo Yadian Israel , Hernández-Trujillo Sergio , Amador-Marrero Ulises 
Published: March 2023

AbstractAlthough there are quantitative studies of the effect of formalin storage on copepod body size, no comparable data exist concerning storage in ethanol. We determined the degree of shrinkage of adult specimens of Parvocalanus crassirostris (Dahl, 1894) preserved in 96% ethanol for different periods of time. Measurements of the prosome of 50 females and 50 males were undertaken in fresh specimens and 7, 15, 30, and 60 days after initial preservation in ethanol. Despite variation among specimens, no significant shrinkage (P &gt; 0.05) was detected on average males. For females, significant shrinkage (mean –4.2%; P &lt; 0.05) was observed after seven days, with no further significant change thereafter.
Autism Spectrum Disorders
Authors: Volkmar Fred R. , Pelphrey Kevin 
Published: March 2023

Abstract
Significant advances in understanding the nature of autism have been made over the past several decades and the pace of research has considerably quickened in recent years. An increased understanding of the social basis of autism (at both the psychological and neurobiological levels) may offer an opportunity to connect basic research in these areas to a growing understanding of possible genetic mechanisms. Early false theoretical leads (e.g., psychogenic models of etiology) have given way to much more sophisticated psychological approaches. The increased research focus on at risk groups (e.g., siblings) and the very earliest psychological and neurobiological manifestation will be critically important in the attempt to more fully understand the complex unfolding of autism as it first develops early in life. Clearly the marriage of these approaches with findings from neuroimaging, neurophysiology, and, ultimately, genetics will offer the prospect of better understanding its pathogenesis and hopefully treatment.
Narcissistic Personality Disorder and Pathological Narcissism
Authors: Pincus Aaron L. 
Published: March 2023

Abstract
The two main perspectives on narcissistic personality pathology are reviewed. First, narcissistic personality disorder (NPD), which is characterized by extreme or excessive grandiosity, is described. Research on its prevalence, stability, and comorbidity is highlighted, followed by a review of substantive research in diagnosed clinical samples. Next, the broader clinical conceptualization of pathological narcissism, which is characterized by grandiosity and vulnerability, is described. Research on pathological narcissism in clinical and nonclinical samples is highlighted. Case examples of NPD and pathological narcissism are provided. Next, the associated clinical features of NPD and pathological narcissism including suicidality, depressed mood, and aggression are discussed. Empirically supported advances in conceptualization, diagnosis, and treatment of narcissistic psychopathology are now emerging. Future research should take advantage of developments in methods, analytics, and technology allowing for novel empirical investigations of temporally dynamic contextualized narcissistic processes.
Anatomical and Histological Structures of Male Reproductive System in Long-Horned Beetle Isotomus speciosus (Schneider, 1787) (Coleoptera: Cerambycidae): Light and Scanning Electron Microscopic Study
Authors: Özyurt Koçakoğlu Nurcan , Candan Selami , Çağlar Üzeyir 
Published: March 2023

Abstract
Isotomus speciosus is a polyphagous insect that damages coniferous and deciduous trees. There is no study on the male reproductive system of I. speciosus although it is an important pest. For this purpose, the male reproductive system anatomy and histology of I. speciosus were investigated using light and scanning electron microscopy. According to the results obtained, the male reproductive system of I. speciosus consists of a pair of testes (each with a pair of separate testis lobes), two pairs of vasa efferentia, a pair of vasa deferentia, an ejaculatory duct, an aedeagus, and three pairs of accessory glands. Each testis lobe has about 65 testis follicles. Testis lobe has sperm development stages (growth, maturation, and differentiation). Each testis lobe is connected to the vas deferens via the vas efferens. There are masses of mature sperm that completely fill lumen of the vas deferens. The vas efferens has cylindrical epithelium, and the vas deferens has cubic epithelium. The vas deferens then opens into the aedeagus by an ejaculatory duct. The ejaculatory duct has an intima layer with spines, monolayer of epithelium, and muscle layer. In this study, similarities and differences in anatomy and histology of male reproductive organs of I. speciosus with other coleopteran species were revealed.
Increased Metabolic Demand During Outside Walking in Darkness With No Vision or With Visual Aid
Authors: Norrbrand Lena , Grönkvist Mikael , Johannesson Björn , Rappe Annika , Sjölin Johan , Eiken Ola 
Published: March 2023

ABSTRACT

Introduction
For tactical reasons, the foot-borne soldiers sometimes undertake nighttime operations. However, the metabolic demand during walking in complete darkness may be markedly increased. The purpose of this study was to investigate if metabolic demand and kinematics would change while walking on a gravel road and a slightly hilly trail in darkness with or without visual aid.

Materials and Methods
Fourteen cadets (11 men and 3 women, age: 25 ± 7 years, height: 178 ± 8 cm, and weight: 78 ± 13 kg) walked at 4 km/h on a straight gravel road and on a slightly hilly forest trail (n = 9). Both trials were performed at nighttime under four different conditions, wearing a headlamp (Light), blindfold (Dark), monocular (Mono), or binocular (Bino) night vision goggles. During the 10-minute walks, oxygen uptake, heart rate, and kinematic data were assessed. Ratings of perceived exertion, discomfort, and mental stress were evaluated after each condition using a category ratio scale. Physiologic and kinematic variables were evaluated using repeated-measures analysis of variance, whereas ratings were evaluated using non-parametric Friedman analysis of variance.

Results
Oxygen uptake was higher in all three conditions with no or limited vision (Dark, Mono, and Bino) than in the Light condition (P ≤ 0.02) when walking on both the gravel road (+5–8%) and the forest trail (+6–14%). Heart rate was higher during the Dark than during the Light condition when walking on the forest trail, whereas there was no difference between conditions on the gravel road. During both trials, gait frequency was higher during the Dark than during the Light, Mono, and Bino conditions. Ratings were generally low during all conditions.

Conclusions
Walking on a gravel road or a forest trail wearing a blindfold or visual aid increased the metabolic demand. Thus, it appears that the metabolic demand is higher during overground walking with night vision goggles than with full vision, which may influence the performance of nighttime operations.
Predictors of damage accrual in patients with antineutrophil cytoplasmic antibody–associated vasculitis: A nationwide prospective study
Authors: Hara Akinori , Sada Ken-ei , Wada Takashi , Amano Koichi , Dobashi Hiroaki , Atsumi Tatsuya , Sugihara Takahiko , Hirayama Kouichi , Banno Shogo , Murakawa Yohko , Hasegawa Midori , Yamagata Kunihiro , Arimura Yoshihiro , Makino Hirofumi , Harigai Masayoshi 
Published: March 2023

ABSTRACT

Objectives
This study elucidated the prognosis and risk factors associated with damage accrual during long-term remission maintenance therapy for patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV).

Methods
We obtained data from 120 patients registered in a nationwide prospective cohort study on remission induction therapy in Japanese patients with AAV and rapidly progressive glomerulonephritis (RemIT-JAV-RPGN), who achieved remission at 24 months after treatment initiation and were followed up for additional 24 months. The primary outcome was the vasculitis damage index (VDI) score at Month 48, and the secondary outcome included risk factors associated with increased total VDI at Month 48.

Results
The understudied patients comprised 52 men and 68 women aged 68 ± 13 years. Between Months 25 and 48, the patients’ survival rate was 95% (114/120). End-stage renal disease developed in seven patients by Month 48, and 64 cases had increased VDI. The multivariable analysis results revealed that oral prednisolone (PSL) doses at Month 24 were associated with damage accrual between Months 24 and 48.

Conclusions
VDI accrual was observed in more than half of patients with AAV during maintenance therapy, and increased VDI scores were associated with oral PSL doses 24 months after initiating remission induction therapy in Japan.
Transfer learning identifies sequence determinants of cell-type specific regulatory element accessibility
Authors: Salvatore Marco , Horlacher Marc , Marsico Annalisa , Winther Ole , Andersson Robin 
Published: March 2023

AbstractDysfunction of regulatory elements through genetic variants is a central mechanism in the pathogenesis of disease. To better understand disease etiology, there is consequently a need to understand how DNA encodes regulatory activity. Deep learning methods show great promise for modeling of biomolecular data from DNA sequence but are limited to large input data for training. Here, we develop ChromTransfer, a transfer learning method that uses a pre-trained, cell-type agnostic model of open chromatin regions as a basis for fine-tuning on regulatory sequences. We demonstrate superior performances with ChromTransfer for learning cell-type specific chromatin accessibility from sequence compared to models not informed by a pre-trained model. Importantly, ChromTransfer enables fine-tuning on small input data with minimal decrease in accuracy. We show that ChromTransfer uses sequence features matching binding site sequences of key transcription factors for prediction. Together, these results demonstrate ChromTransfer as a promising tool for learning the regulatory code.
Surveillance and Stewardship: Where Infection Prevention and Antimicrobial Stewardship Intersect
Authors: Tenover Fred C , Goff Debra A 
Published: March 2023

Abstract
Colonization with multidrug-resistant organisms (MDROs) is a risk factor for subsequent infection. Surveillance for MDROs, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Enterobacterales, and carbapenemase-producing organisms, is commonly conducted in hospitals to prevent spread of MDROs, in part to reduce the potential for additional infections. Although colonization is a risk factor for infection, data on colonization with various MDROs are often not considered when selecting anti-infective therapy. There are conflicting data on the strength of the positive and negative predictive values of the colonization test results to guide therapeutic strategies. Defining therapeutic strategies for patients with complicated or drug-resistant infections or to select antimicrobial prophylaxis before performing prostate biopsies often falls under the purview of the antimicrobial stewardship team. Should colonization data, which are often present in the patient's medical record from routine infection prevention measures, be reviewed before selecting therapy for infections or for prophylaxis? In this perspective, we will explore the intersection of infection control and antimicrobial stewardship activities.