bluuebunny/crossref_metadata_2025_split huggingface dataset:
A perfect match? A semiotic analysis of the wife figure in four early picaresque novels
Authors: Gussago Luigi 
Published: March 2023

Abstract
Picaresque fiction, or the so-called tale of roguery, focuses mainly on the adventures of a male protagonist. Although women characters rarely take the lead, they mark significant transitions in the narrative syntax. Mothers, wives, and lovers reject stereotypical role models and are invested with the potential of initiating the picaro to his life stages. This study will concentrate on the wife as a catalyst of semiotic value beyond her appointed role, exploring a corpus of four works published between 1554 and 1626: Lazarillo de Tormes, The Unfortunate Traveller, Guzmán de Alfarache, and El Buscón. In these narratives, wives oppose their fate of pure Objects in a conjugal contract, and become Subjects, Antagonists or Destinators, assertive “actants” (Greimas) in the semiotic grammar of narrative. My purpose is to re-evaluate, in deep-structure narrative terms, the significance of women characters in the largely male-centred, misogynist picaresque.
Possible alternatives for using kraft lignin as activated carbon in pulp mills – a review
Authors: Condezo Castro Tatiana Aurora , Cardoso Marcelo , Passos Rezende Ana Augusta , Oliveira Carneiro Angélica de Cássia , Quartaroli Larissa , Mudadu Silva Cláudio 
Published: March 2023

Abstract
The uses of kraft lignin (KL), obtained from the black liquor (BL) in the pulping process, allow the production of activated carbon (AC), a product with high added value in the pulp mill. The AC can be used in three different sectors in a cellulose pulp mill: sectorial treatment of the cellulosic pulp bleaching filtrates; wastewater treatment; and in the treatment of water received by the mill. Thus, this article considers the steps in the production of AC, their types, and the advantages and challenges of its use in the kraft cellulose pulp mill as well as in other industries.
Role of fiber density of amine functionalized dendritic fibrous nanosilica on CO2 capture capacity and kinetics
Authors: Singh Baljeet , Polshettiwar Vivek 
Published: March 2023

Abstract
Textural properties of the solid sorbents are critical to tuning their CO2 capture performance. In this work, we studied the effect of fiber density (in turn, pore size, distribution, and accessibility) on CO2 capture capacity and kinetics. CO2 solid sorbents were prepared by physisorption of tetraethylenepentamine (TEPA) molecules on dendritic fibrous nanosilica (DFNS) with varying fiber density. Among the various DFNS, the DFNS with moderate fiber density [DFNS-3] showed the best CO2 capture capacity under the flue gas condition. The maximum CO2 capture capacity achieved was 24.3 wt % (5.53 mmol/g) at 75 °C for DFNS-3 under humid gas conditions. Fiber density also played a role in the kinetics of CO2 capture. DFNS-1 with dense fiber density needed ∼10.4 min to reach 90 % capture capacity, while DFNS-3 (moderate fiber density) needed only 6.4 min, which further decreased to 5.9 min for DFNS-5 with lightly dense fibers. The DFNS-impregnated TEPA also showed good recyclability during 21 adsorption and desorption cycles under humid and dry conditions. The total CO2 capture capacity of DFNS-3 (14.7) in 21 cycles was 108.9 and 105.0 mmol/g under humid and dry conditions, respectively. Adsorption lifetime calculation and recyclability confirmed the fiber density-dependent CO2 capture performance.
Effects of nano-silica on the crystallization, structure, and mechanical properties of crosslinked ethylene-octene copolymer/nano-silica composites
Authors: Bai Nan , Shi Ying , Wang Yuan-Xia , Liu Li-Zhi , Song Li-Xin , Wang Chen-Chen , Song Li-Fu 
Published: March 2023

Abstract
Nano-silica (SiO2) has been widely used to fill rubbers (crosslinked) and usual polyolefin elastomers (POEs). SiO2 filled POE with crystalline structure can also be crosslinked. Crystallization, structure, and mechanical properties of crosslinked POE/SiO2 composites can be affected by SiO2. In this paper, crosslinked POE/SiO2 composites were obtained through two different methods: dynamic crosslinking in molten state and static crosslinking. For the non-crosslinked and static crosslinked composites, SiO2 had a more significant effect on the nucleation in non-crosslinked POE than in static crosslinked POE. For the dynamic crosslinked composite, SiO2 and crosslinking points hindered the mobility of POE chains and suppressed the POE crystallization, resulting in smaller and fewer crystals. Dynamic mechanical analysis showed that the SiO2 and POE were compatible, as evidenced by the lower tan(δ) value in SiO2-filled samples. The latter was more consistent with the higher tensile strength and elongation at break for the non-crosslinked and static crosslinked composites than for the non-filled samples. However, the dynamic crosslinked composite exhibited the worst elongation at break, resulting from the lowest number of crystals and shortened molecular chains due to the shearing that occurred during crosslinking process. The SiO2 had no observable effect on the permanent deformation of samples.
Status and frontier analysis of indoor PM2.5-related health effects: a bibliometric analysis
Authors: Zhao Xinying , Xu Hailin , Li Yan , Liu Yufan , Guo Caixia , Li Yanbo 
Published: March 2023

Abstract
Epidemiological data indicate atmospheric particulate matter, especially fine particulate matter (PM2.5), has many negative effects on human health. Of note, people spend about 90% of their time indoors. More importantly, according to the World Health Organization (WHO) statistics, indoor air pollution causes nearly 1.6 million deaths each year, and it is considered as one of the major health risk factors. In order to obtain a deeper understanding of the harmful effects of indoor PM2.5 on human health, we used bibliometric software to summarize articles in this field. In conclusion, since 2000, the annual publication volume has increased year by year. America topped the list for the number of articles, and Professor Petros Koutrakis and Harvard University were the author and institution with the most published in this research area, respectively. Over the past decade, scholars gradually paid attention to molecular mechanisms, therefore, the toxicity can be better explored. Particularly, apart from timely intervention and treatment for adverse consequences, it is necessary to effectively reduce indoor PM2.5 through technologies. In addition, the trend and keywords analysis are favorable ways to find out future research hotspots. Hopefully, various countries and regions strengthen academic cooperation and integration of multi-disciplinary.
Attractor-Like Dynamics Extracted from Human Electrocorticographic Recordings Underlie Computational Principles of Auditory Bistable Perception
Authors: Melland Pake , Curtu Rodica 
Published: March 2023

In bistable perception, observers experience alternations between two interpretations of an unchanging stimulus. Neurophysiological studies of bistable perception typically partition neural measurements into stimulus-based epochs and assess neuronal differences between epochs based on subjects' perceptual reports. Computational studies replicate statistical properties of percept durations with modeling principles like competitive attractors or Bayesian inference. However, bridging neuro-behavioral findings with modeling theory requires the analysis of single-trial dynamic data. Here, we propose an algorithm for extracting nonstationary timeseries features from single-trial electrocorticography (ECoG) data. We applied the proposed algorithm to 5-min ECoG recordings from human primary auditory cortex obtained during perceptual alternations in an auditory triplet streaming task (six subjects: four male, two female). We report two ensembles of emergent neuronal features in all trial blocks. One ensemble consists of periodic functions that encode a stereotypical response to the stimulus. The other comprises more transient features and encodes dynamics associated with bistable perception at multiple time scales: minutes (within-trial alternations), seconds (duration of individual percepts), and milliseconds (switches between percepts). Within the second ensemble, we identified a slowly drifting rhythm that correlates with the perceptual states and several oscillators with phase shifts near perceptual switches. Projections of single-trial ECoG data onto these features establish low-dimensional attractor-like geometric structures invariant across subjects and stimulus types. These findings provide supporting neural evidence for computational models with oscillatory-driven attractor-based principles. The feature extraction techniques described here generalize across recording modality and are appropriate when hypothesized low-dimensional dynamics characterize an underlying neural system.SIGNIFICANCE STATEMENTIrrespective of the sensory modality, neurophysiological studies of multistable perception have typically investigated events time-locked to the perceptual switching rather than the time course of the perceptual states per se. Here, we propose an algorithm that extracts neuronal features of bistable auditory perception from largescale single-trial data while remaining agnostic to the subject's perceptual reports. The algorithm captures the dynamics of perception at multiple timescales, minutes (within-trial alternations), seconds (durations of individual percepts), and milliseconds (timing of switches), and distinguishes attributes of neural encoding of the stimulus from those encoding the perceptual states. Finally, our analysis identifies a set of latent variables that exhibit alternating dynamics along a low-dimensional manifold, similar to trajectories in attractor-based models for perceptual bistability.
Rule Abstraction Is Facilitated by Auditory Cuing in REM Sleep
Authors: Pereira Sofia Isabel Ribeiro , Santamaria Lorena , Andrews Ralph , Schmidt Elena , Van Rossum Mark C.W. , Lewis Penelope 
Published: March 2023

Sleep facilitates abstraction, but the exact mechanisms underpinning this are unknown. Here, we aimed to determine whether triggering reactivation in sleep could facilitate this process. We paired abstraction problems with sounds, then replayed these during either slow-wave sleep (SWS) or rapid eye movement (REM) sleep to trigger memory reactivation in 27 human participants (19 female). This revealed performance improvements on abstraction problems that were cued in REM, but not problems cued in SWS. Interestingly, the cue-related improvement was not significant until a follow-up retest 1 week after the manipulation, suggesting that REM may initiate a sequence of plasticity events that requires more time to be implemented. Furthermore, memory-linked trigger sounds evoked distinct neural responses in REM, but not SWS. Overall, our findings suggest that targeted memory reactivation in REM can facilitate visual rule abstraction, although this effect takes time to unfold.SIGNIFICANCE STATEMENTThe ability to abstract rules from a corpus of experiences is a building block of human reasoning. Sleep is known to facilitate rule abstraction, but it remains unclear whether we can manipulate this process actively and which stage of sleep is most important. Targeted memory reactivation (TMR) is a technique that uses re-exposure to learning-related sensory cues during sleep to enhance memory consolidation. Here, we show that TMR, when applied during REM sleep, can facilitate the complex recombining of information needed for rule abstraction. Furthermore, we show that this qualitative REM-related benefit emerges over the course of a week after learning, suggesting that memory integration may require a slower form of plasticity.
How to target vascular leakage in retinopathy: could a lipid tighten the pipes?
Authors: Iruela‐Arispe M Luisa 
Published: March 2023

Retinopathy is one of the more severe complications associated with diabetes. Targeting vascular pathology has shown benefits, but current therapies are costly and have limitations. In this issue of EMBO Molecular Medicine, Niaudet et al report that the activation of the S1PR1 receptor in endothelial cells is able to block abnormal permeability, neovascular tuft development, and resolve pathological vascular lesions associated with hypoxia‐driven retinopathy.
Actores sociales y alternativas de coordinación para el desarrollo territorial.
Authors: Pizaña Vidal Hugo A. 
Published: March 2023

“Actores sociales y alternativas de coordinación para el desarrollo territorial” es una obra que reúne una serie de estudios sociales con un enfoque territorial, lograda gracias al esfuerzo colectivo de estudiantes y docentes de posgrado de tres instituciones académicas del Sur y Occidente de México. El libro ofrece al lector información detalladas de investigaciones empíricas que relatan las experiencias de actores locales que se interrelacionan y coordinan para confrontar diversas problemáticas que impone la globalización capitalista; ya sea a través de mecanismos que buscan propiciar formas alternativas de desarrollo o generar vías alternativas al desarrollo para mejorar las condiciones de vida de ciertos grupos sociales, o bien para reivindicar saberes y epistemologías -del sur- que son escasamente reconocidas por la racionalidad moderna. Propone, con tales experiencias, comprender los procesos de configuración de los territorios desde una mirada que no solo observa cómo actores hegemónicos imponen instituciones, reglas y normas que rigen la vida socioeconómica y productiva, sino también cómo los actores locales, desde un ámbito cotidiano, las adaptan, resisten e incluso rechazan.
El uso de la cartografía social teatral con niños y niñas de Fómeque y Choachí, Colombia
Authors: Ramos Tique Daniela Alejandra , Movilla Vergara José Antonio , Rozo Álvarez Angela Lucia , Rodríguez Portillo Carla 
Published: March 2023

Este artículo tiene como objetivo demostrar que el uso de la cartografía social, en conjunto con técnicas teatrales en investigaciones con niños y niñas, permite una comprensión ampliada de las representaciones sobre el territorio y las experiencias cotidianas que se desarrollan en este. Para ello, se abordan teóricamente la geografía de la infancia, las representaciones sociales y el territorio. Se propone una metodología llamada cartografía social teatral (CST) como contribución al conjunto de metodologías participativas útiles en los estudios ambientales. La CST se aplicó a niños y niñas de las escuelas rurales de las veredas Hato Viejo, Chinia, Guachavita y Mortiñal, en el municipio de Fómeque, y las veredas de La Maza, El Rosario y La Caja, en el municipio de Choachí, ubicados en Colombia. Mediante esta metodología, se identificaron los aspectos más representativos del territorio para la población infantil. También, los elementos involucrados en la construcción de sus representaciones sobre el Parque Nacional Natural Chingaza, tales como el discurso institucional de conservación de Parques Naturales de Colombia y la transmisión oral de las experiencias de sus abuelos y abuelas sobre el páramo de Chingaza, antes de la llegada de las instituciones estatales. En los discursos de los niños y las niñas participantes de la investigación resaltan la fauna, el agua y la noción abstracta de la naturaleza como elemento que se mezcla entre el paisaje, lleno de fantasía y realidad.
Abstract
This article aims to demonstrate that the use of social cartography, along with theatrical techniques in investigations with children, allows a wider understanding of the representations within the territory and the daily experiences that take place in it. The concepts of the geography of childhood, social representations and territory are theoretically addressed. The methodology of Theater Social Cartography is applied to the work with children in rural schools in the villages of Hato Viejo, Chinia, Guachavita and Mortiñal in the municipality of Fómeque, and the villages of La Maza, El Rosario and La Caja in the municipality of Choachí, located in Colombia. Through this method, the most representative aspects, according to the children of the aforementioned schools, as well as the elements involved in the construction of their representations about the Parque Nacional Natural Chingaza, such as the institutional discourse of conservation of Parques Naturales and the oral transmission of the experiences of their grandparents and grandmothers about the Park before the arrival of institutions are analyzed. Elements such as fauna, water, and the abstract notion of nature as an element that mixes between the landscape full of fantasy and reality, stand out in the speeches of the children participating in this research.
Evaluación del SCAE-Agua como herramienta para guiar la sostenibilidad del agua urbana
Authors: Torres Lopez Susana , Rodríguez-Labajos Beatriz 
Published: March 2023

Entre los diferentes métodos analíticos que se pueden utilizar para analizar la gestión y las políticas sostenibles del agua, Naciones Unidas promueve la metodología estandarizada del Sistema de Contabilidad Ambiental y Económica para el Agua (SCAE-Agua). Si bien se ha probado a escala subnacional, su implementación en entornos urbanos está comenzando. El objetivo del artículo es evaluar hasta qué punto las herramientas disponibles dentro del SCAE-Agua pueden guiar la gestión sostenible del agua urbana. Se emplea una metodología multidimensional, preponderantemente cualitativa. Sobre la base de la información compilada del SCAE-Agua e información complementaria para aspectos sociales, el marco del SCAE-Agua fue evaluado como una herramienta para responder a los retos de sostenibilidad urbana, en las ciudades en crecimiento de América Latina. Se concluye que la implementación del SCAE-Agua en el ámbito urbano permite recopilar información sobre cantidad y calidad de los recursos hídricos, además de la economía de la ciudad. Ello es útil para organizar la información sobre los flujos y la productividad económica del agua, y para detectar presiones urbanas sobre la calidad de esta. Sin embargo, este marco pierde información necesaria para gestionar el agua como un elemento holístico entrelazado en los procesos socioambientales en las áreas urbanas. Una brecha clave identificada es la equidad del agua.
La implementación del SCAE-Agua en una ciudad latinoamericana demostró su utilidad para recopilar información sobre cantidad y calidad de los recursos hídricos, además de la economía de la ciudad. Esto es útil para organizar la información sobre los flujos de agua y la productividad económica del agua, y para detectar presiones urbanas claves sobre la calidad del agua. Sin embargo, este marco pierde información relevante necesaria para gestionar el agua como un elemento holístico entrelazado en los procesos socioambientales en las áreas urbanas. Una brecha clave identificada es la equidad del agua.
Blockchain como Soporte tecnológico de las Cadenas de Suministro Marítimas
Authors: Guzman Arjona Erika Maria , Luque Cervantes José Manuel , Ariza Avendaño Rafael Antonio , Vanegas Tatis Andrés Genaro 
Published: March 2023

El transporte marítimo representa el 90% del movimiento internacional de carga, siendo motor de la economía global, pero enfrentando altos costos administrativos y el impacto negativo en el medio ambiente. La tecnología Blockchain se ha convertido en catalizador positivo para la eficiencia de los procesos administrativos del sector marítimo apoyados en la transmisión de datos en tiempo real: eliminando la presentación de documentos impresos, agilizando la operación logística de carga, mejorando el control de la trazabilidad y proporcionando una solución respetuosa con el medio ambiente. Blockchain representa un ahorro de costos y la creación de sistemas comerciales eficientes en todas las partes involucradas. El presente artículo de revisión pretende identificar las cualidades del Blockchain en las cadenas de suministro marítima
Comparison and evaluation of efficacy of olfactory and taste distraction in managing anxious pediatric patients during radiovisiography
Authors: Khan Anam Khushboo , Kalra Gauri , Saraf Bhavna Gupta , Sheoran Neha , Kakkar Tanya , Lakhanpal Pallavi 
Published: March 2023

Due to dental anxiety & fear, young children tend to be more anxious even at the times of basic clinical examination and investigative procedures such as taking IOPAs, however, with the advent of RVGs, taking X-rays have become less cumbersome. A study was planned for comparison and evaluation of olfactory distraction utilizing aromatherapy, taste distraction and conventional method (Tell-Show-Do) in managing fearful children aged 4-7 years during radiovisiography (RVG). A total of 45 children (4-7 years old) were included and 3 groups (15 each) were formed and radiographs were taken with the help of RVG (radiovisigraphy) under aromatherapy, with taste distraction and using control- Tell Show Do technique. Pre- and Post- anxiety scores were measured using physiological measures- pulse and respiratory rate, oxygen saturation and Venham’s picture test. Statistical Package for Social Sciences (SPSS) version 21, IBM Inc, was used for statistical analysis.Both the test groups (aromatherapy and taste distraction group) when compared with control group, exhibited noteworthy post-treatment variation in anxiety level scores. No statistical significance was seen amongst taste distraction and aromatherapy group, although aromatherapy exhibited superior results in comparison to taste distraction. Both taste distraction using lollipop/candy and aromatherapy employing lavender essential oil are efficacious in management of anxiety among children, however aromatherapy unveils a better result in comparison. To conclude, a combination or individual use of less invasive techniques may be executed effectively in handling pediatric dental patients.
CAR T-cell Therapy of Hematologic Malignancies: An Update in Targeted Antigens
Authors: Sadeqi Nezhad Muhammad , Rajabzadeh Alireza , Dehghani Firoozabadi Ali 
Published: March 2023

Immunotherapy with genetically engineered T-cells that express the chimeric antigen receptor (CAR) has raised hopes for the treatment of pediatric malignancies. Although CAR T-cell development is on a fast-moving pace and evolution, the context of exploring novel targetable antigens has been neglected. In this review study, we analyze the prominent hematologic antigens targeted by engineered T-cells in both preclinical and clinical aspects. Furthermore, we discuss the outcomes of CAR-based therapy in hematologic cancers from different viewpoints of treatment and provide some critical features for additional considerations. Almost certainly, most of the engineered T-cells redirected against hematologic disorders aim at conventional target antigens rather than targeting an ideal target antigen that is exclusively expressed on cancerous cells and restricted to normal tissues. CAR-based clinical trials in hematologic cancers have often dealt with CD19, followed by BCMA, CD22, and CD20 antigens. Besides, most of the scFvs used in the CAR structure are derived from murine antibodies, which may raise the concern about immunogenicity by reducing the persistence of modified T-cells. Nevertheless, short- and long-term life-threatening toxicities and the development of escape mechanisms that result in resistance and antigen loss are not thoroughly understood yet. The ultimate goal of using modified CAR T-cells is to make them effective and curative. Therefore, a better understanding of all the features pertaining to target antigens is imperative. Also, the methods to identify candidate target antigens and manage the associated obstacles of CAR T-cells should be evaluated and prioritized.