bluuebunny/crossref_metadata_2025_split huggingface dataset:
The wealth of shared resources: Improving molecular taxonomy using eDNA and public databases
Authors: Fleming James F. 
Published: February 2023

AbstractPublic databases such as the NCBI's GenBank have been used as repositories for genomic studies for more than 30 years. In this time, our understanding of the natural world, and especially the genomic world, has expanded vastly, and the size of these databases represent this genomic revolution. Databases like GenBank now help populate many molecular studies, supplementing a researcher's newly gathered data with publicly available sequences. Despite this, older sequence records, particularly those from understudied taxa, are frequently not updated in line with this burgeoning understanding, and this means that analyses that leverage this public data – from BLAST through to phylogenetic analyses – cannot do so with the full force of its collective understanding. This is particularly true for environmental DNA (eDNA) records, where older sequence records may identify sequences only to the phylum level, limiting their use in many studies. Here, with a case study of tardigrade 18S sequences, the family identities of 630 sequences, previously only identified to the phylum level, were established using 501 family, genus and species level 18S sequences, effectively doubling the depth and taxonomic resolution of tardigrade 18S sequences in GenBank.
Characterizing candidates for Cannon's conjecture from geometric measure theory
Authors: Cheetham‐West Tamunonye , Nolte Alexander 
Published: February 2023

AbstractWe show that recent work of Song implies that torsion‐free hyperbolic groups with Gromov boundary arerealized as fundamental groups of closed 3‐manifolds of constant negative curvature if and only if the solution to an associated spherical Plateau problem for group homology is isometric to such a 3‐manifold, and suggest some related questions.
Human disturbances dominated the unprecedentedly high frequency of Yellow River flood over the last millennium
Authors: Yu Shi-Yong , Li Wen-Jia , Zhou Liang , Yu Xuefeng , Zhang Qiang , Shen Zhixiong 
Published: February 2023

A warming climate may increase flood hazard through boosting the global hydrological cycle. However, human impact through modifications to the river and its catchment is not well quantified. Here, we show a 12,000-year-long record of Yellow River flood events by synthesizing sedimentary and documentary data of levee overtops and breaches. Our result reveals that flood events in the Yellow River basin became almost an order of magnitude more frequent during the last millennium than the middle Holocene and 81 ± 6% of the increased flood frequency can be ascribed to anthropogenic disturbances. Our findings not only shed light on the long-term dynamics of flood hazards in this world’s most sediment-laden river but also inform policy of sustainable management of large rivers under anthropogenic stress elsewhere.
Nonvanishing gravitational contribution to matter beta functions for vanishing dimensionful regulators
Authors: de Brito Gustavo P. , Eichhorn Astrid 
Published: February 2023

AbstractWe explore the effect of quantum gravity on matter within a Renormalization Group framework. First, our results provide an explicit example of how misleading conclusions can be drawn by analyzing the gravitational contributions to beta functions, instead of analyzing universal quantities, such as critical exponents, that can be extracted from the beta functions. This could be key to explain differences between perturbative studies and Functional Renormalization Group studies. Second, we strengthen the evidence that asymptotically safe gravity could generate a predictive ultraviolet completion for matter theories with gauge interactions, even in the limit of vanishing dimensionful regulator function. We also find that the situation can be more subtle with higher-order, gravity-induced matter interactions.
Radiating stars and Riccati equations in higher dimensions
Authors: Naidoo Noeleen , Maharaj Sunil D. , Govinder Keshlan S. 
Published: February 2023

AbstractThe objective of this study is to investigate spherically symmetric radiating stars undergoing gravitational collapse, in higher dimensional general relativity, inclusive of acceleration, expansion, shear, an electromagnetic field and a cosmological constant. Methods that can be used to obtain exact solutions to the boundary condition with/without a linear equation state are studied. Two distinct approaches are investigated. In the first approach, the boundary condition is expressed as a Riccati equation in terms of one of the dependent variables, and restrictions are placed to obtain new exact solutions. In the second approach, transformations that map the boundary condition into a new Riccati equation are investigated. The resulting new transformed equation is solved, by placing restrictions on the coefficients, to obtain new exact models. Special properties of the transformation are shown when appropriate restrictions on the parameters of the transformation are placed. This allows the order of the boundary condition to be reduced from a second order partial differential equation into a first order partial differential equation. The versatility of the transformation on other equations is exhibited when new solutions to the system of equations consisting of both the boundary condition and equation of state are obtained. When the dimension is set to four, some known solutions are recovered. It is shown that horizons can be identified by using a special case of the transformation. Our results elucidates the importance of the use of transformations that map the coordinates of differential equations into new and different coordinate systems.
Polarized image of a rotating black hole surrounded by a cold dark matter halo
Authors: Qin Xin , Chen Songbai , Zhang Zelin , Jing Jiliang 
Published: February 2023

AbstractWe have studied the polarized image of an equatorial emitting ring around a rotating black hole surrounded by a cold dark matter (CDM) halo. Results show that the CDM halo density has the similar effects of the halo’s characteristic radius on the polarized image for the black hole. The effects of the CDM halo on the polarized image depend on the magnetic field configuration, the fluid velocity and the observed inclination. With the increase of the CDM halo parameters, the observed polarization intensity decreases when the magnetic field lies in equatorial plane, but in the case where the magnetic field is perpendicular to the equatorial plane, the change of the observed polarization intensity with CDM halo also depends on the position of the emitting point in the ring. The change of the electric vector position angle (EVPA) with the CDM halo becomes more complicated. Our results also show that the influence of the CDM halo on the polarized image is generally small, which are consistent with the effects of dark matter halo on black hole shadows. These results could help to further understand dark matter from black hole images.
Magnetic monopoles with no strings attached: a portal to the dark side of dual electrodynamics
Authors: Govaerts Jan 
Published: February 2023

AbstractIt has long been known that in the absence of electric charges and currents, Maxwell’s electromagnetism in 4 dimensional vacuum Minkowski space-time is invariant under SO(2) dual transformations that mix its electric and magnetic fields. Extending this symmetry to include the coupling to electrically charged matter, requires a dual coupling to magnetically charged matter as well, leading to Maxwell equations for SO(2) dual electrodynamics. Based on a doubled ensemble of SO(2) dual 4-vector gauge potentials which does away with the need of Dirac string singularities for magnetic monopoles, a local Lagrangian action principle for SO(2) dual electromagnetism is known, which manifestly displays all the required space-time and internal symmetries, and reduces to the experimentally well established Maxwell electrodynamics in the absence of magnetic charges and currents. Applying the same considerations for the matter action of electrically and magnetically charged point particles, a unique SO(2) dual generalised Lorentz force is identified for SO(2) dual electrodynamics, truly different from the usual SO(2) dual invariant choice motivated by simplicity, but yet made arbitrarily and which does not derive from some action principle. This generalised Lorentz force involves a single real and new coupling constant of unknown value, without the requirement of a Dirac–Schwinger–Zwanziger quantisation condition for electric and magnetic charges of dyons. A physical consequence for SO(2) dual electrodynamics of this coupling constant if nonvanishing, is to open a channel, or portal between the otherwise mutually totally “dark” sectors of electric and magnetic charges for electromagnetic interactions.
Impact of health literacy and social support on medication adherence in patients with hypertension: a cross-sectional community-based study
Authors: Guo Aizhen , Jin Hua , Mao Jianbo , Zhu Weihong , Zhou Ye , Ge Xuhua , Yu Dehua 
Published: February 2023

Abstract
Background
Previous studies have examined the associations of health literacy and social support with medication adherence among patients with hypertension. However, limited evidence exists regarding the mechanisms underlying the relationship between these factors and medication adherence.

Purpose
To explore the prevalence of medication adherence and its determinants in patients with hypertension in Shanghai.

Methods
A community-based cross-sectional study was conducted among 1697 participants with hypertension. We collected sociodemographic and clinical characteristics as well as data regarding health literacy, social support, and medication adherence using questionnaires. We examined interactions among the factors using a structural equation model.

Results
The participants included 654 (38.54%) patients with a low degree of medication adherence and 1043 (61.46%) patients with a medium/high degree of adherence. Social support directly influenced adherence (β = 0.165, P < 0.001) and indirectly influenced adherence through health literacy (β = 0.087, P < 0.001). Health literacy directly influenced adherence (β = 0.291, P < 0.001). Education indirectly affected adherence through both social support (β = 0.048, P < 0.001) and health literacy (β = 0.080, P < 0.001). Moreover, there was a sequential mediating effect of social support and health literacy on the association between education and adherence (β = 0.025, P < 0.001). After controlling for age and marital status, similar results were also obtained, indicating a good model fit.

Conclusions
The degree of medication adherence among hypertensive patients needs to improve. Health literacy and social support had both direct and indirect effects on adherence, and thus, these factors should be considered as tools to improve adherence.
A descriptive study of abdominal complications in patients with mild COVID-19 presenting to the emergency department: a single-center experience in Japan during the omicron variant phase
Authors: Maruyama Shuhei , Wada Daiki , Oishi Takahiro , Saito Fukuki , Yoshiya Kazuhisa , Nakamori Yasushi , Kuwagata Yasuyuki 
Published: February 2023

Abstract
Background
COVID-19 is widely known to induce a variety of extrapulmonary manifestations. Gastrointestinal symptoms have been identified as the most common extra-pulmonary manifestations of COVID-19, with an incidence reported to range from 3 to 61%. Although previous reports have addressed abdominal complications with COVID-19, these have not been adequately elucidated for the omicron variant. The aim of our study was to clarify the diagnosis of concomitant abdominal diseases in patients with mild COVID-19 who presented to hospital with abdominal symptoms during the sixth and seventh waves of the pandemic of the omicron variant in Japan.

Methods
This study was a retrospective, single-center, descriptive study. In total, 2291 consecutive patients with COVID-19 who visited the Department of Emergency and Critical Care Medicine, Kansai Medical University Medical Center, Osaka, Japan, between January 2022 and September 2022 were potentially eligible for the study. Patients delivered by ambulance or transferred from other hospitals were not included. We collected and described physical examination results, medical history, laboratory data, computed tomography findings and treatments. Data collected included diagnostic characteristics, abdominal symptoms, extra-abdominal symptoms and complicated diagnosis other than that of COVID-19 for abdominal symptoms.

Results
Abdominal symptoms were present in 183 patients with COVID-19. The number of patients with each abdominal symptom were as follows: nausea and vomiting (86/183, 47%), abdominal pain (63/183, 34%), diarrhea (61/183, 33%), gastrointestinal bleeding (20/183, 11%) and anorexia (6/183, 3.3%). Of these patients, 17 were diagnosed as having acute hemorrhagic colitis, five had drug-induced adverse events, two had retroperitoneal hemorrhage, two had appendicitis, two had choledocholithiasis, two had constipation, and two had anuresis, among others. The localization of acute hemorrhagic colitis was the left-sided colon in all cases.

Conclusions
Our study showed that acute hemorrhagic colitis was characteristic in mild cases of the omicron variant of COVID-19 with gastrointestinal bleeding. When examining patients with mild COVID-19 with gastrointestinal bleeding, the potential for acute hemorrhagic colitis should be kept in mind.
Image quality comparison of lower extremity CTA between CT routine reconstruction algorithms and deep learning reconstruction
Authors: Zhang Daming , Mu Chunlin , Zhang Xinyue , Yan Jing , Xu Min , Wang Yun , Wang Yining , Xue Huadan , Chen Yuexin , Jin Zhengyu 
Published: February 2023

Abstract
Background
To evaluate the image quality of lower extremity computed tomography angiography (CTA) with deep learning–based reconstruction (DLR) compared to model-based iterative reconstruction (MBIR), hybrid-iterative reconstruction (HIR), and filtered back projection (FBP).

Methods
Fifty patients (38 males, average age 59.8 ± 19.2 years) who underwent lower extremity CTA between January and May 2021 were included. Images were reconstructed with DLR, MBIR, HIR, and FBP. The standard deviation (SD), contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), noise power spectrum (NPS) curves, and the blur effect, were calculated. The subjective image quality was independently evaluated by two radiologists. The diagnostic accuracy of DLR, MBIR, HIR, and FBP reconstruction algorithms was calculated.

Results
The CNR and SNR were significantly higher in DLR images than in the other three reconstruction algorithms, and the SD was significantly lower in DLR images of the soft tissues. The noise magnitude was the lowest with DLR. The NPS average spatial frequency (fav) values were higher using DLR than HIR. For blur effect evaluation, DLR and FBP were similar for soft tissues and the popliteal artery, which was better than HIR and worse than MBIR. In the aorta and femoral arteries, the blur effect of DLR was worse than MBIR and FBP and better than HIR. The subjective image quality score of DLR was the highest. The sensitivity and specificity of the lower extremity CTA with DLR were the highest in the four reconstruction algorithms with 98.4% and 97.2%, respectively.

Conclusions
Compared to the other three reconstruction algorithms, DLR showed better objective and subjective image quality. The blur effect of the DLR was better than that of the HIR. The diagnostic accuracy of lower extremity CTA with DLR was the best among the four reconstruction algorithms.
Is obesity a risk factor for melanoma?
Authors: Arbel Yuval , Arbel Yifat , Kerner Amichai , Kerner Miryam 
Published: February 2023

Abstract
Objectives
Are twofold: 1) to estimate the relationship between obesity (BMI ≥30) and the prevalence of melanoma in different US states and 2) to examine the possibility of defining a new risk group. This might enhance the possibility of detection, which in turn, might increase the survival rates of patients.

Study design
A cohort Study, based on data at the US statewide level in 2011–2017, where the dependent variable (the annual new melanoma cases per 100,000 persons) is adjusted for age.

Method
Quadratic regression analysis. This model permits a non-monotonic variation of obesity with new melanoma cases adjusted for age, where the control variable is the level of UV radiation.

Results
Demonstrate a negative correlation between obesity and incidence of melanoma. This outcome is further corroborated for Caucasians.

Conclusions
We should continue to establish primary prevention of melanoma by raising photo protection awareness and secondary prevention by promoting skin screening (by physician or self) among the entire population group in all BMI ranges. Advanced secondary melanoma prevention including noninvasive diagnosis strategies including total body photography, confocal microscopy, AI strategies should focus the high-risk sub group of Caucasians with BMI < 30.
Serum Rcn3 level is a potential diagnostic biomarker for connective tissue disease-associated interstitial lung disease and reflects the severity of pulmonary function
Authors: Ding Fangping , Yang Liu , Wang Yingfei , Wang Jing , Ma Yingmin , Jin Jiawei 
Published: February 2023

Abstract
Background
Although reticulocalbin 3 (Rcn3) has a critical role in alveolar epithelial function as well as in pathogenesis of pulmonary fibrosis, no study has yet examined its diagnostic and prognostic values for interstitial lung disease (ILD). This study aimed to evaluate Rcn3 as a potential marker in differential diagnosis of idiopathic pulmonary fibrosis (IPF) and connective tissue disease-associated interstitial lung disease (CTD-ILD) and in reflecting the severity of disease.

Methods
This was a retrospective observational pilot study included 71 ILD patients and 39 healthy controls. These patients were stratified into IPF group (39) and CTD-ILD group (32). The severity of ILD was evaluated through pulmonary function test.

Results
Serum Rcn3 level was statistically higher in CTD-ILD patients than that in IPF patients (p = 0.017) and healthy controls (p = 0.010). Serum Rcn3 further showed statistically negative correlation with pulmonary function indexes (TLC% pred and DLCO% pred) and positive correlation with inflammatory indexes (CRP and ESR) (r =  − 0.367, p = 0.039; r =  − 0.370, p = 0.037; r = 0.355, p = 0.046; r = 0.392, p = 0.026, respectively) in CTD-ILD patients rather than IPF patients. ROC analysis demonstrated that serum Rcn3 had superior diagnostic value for CTD-ILD and a cutoff value of 2.73 ng/mL had a sensitivity of 69%, a specificity of 69% and an accuracy of 45% for diagnose of CTD-ILD.

Conclusions
Serum Rcn3 levels might be a clinically useful biomarker in screening and evaluating CTD-ILD.
Relative decline in serum albumin help to predict anastomotic leakage for female patients following sphincter-preserving rectal surgery
Authors: Hu Kang , Tan Ke , Shang Quanzhen , Li Chao , Zhang Zhe , Huang Bin , Zhao Song , Li Fan , Zhang Anping , Li Chunxue , Liu Baohua , Tong Weidong 
Published: February 2023

Abstract
Background
Patients with normal preoperative serum albumin still suffer from a significant reduction in serum albumin after major abdominal surgery. The current study aims to explore the predictive value of ∆ALB for AL in patients with normal serum albumin and examine whether there is a gender difference in the prediction of AL.

Methods
Medical reports of consecutive patients undergoing elective sphincter-preserving rectal surgery between July 2010 and June 2016 were reviewed. Receiver operating characteristic (ROC) analysis was adopted to examine the predictive ability of ∆ALB and determine the cut-off value according to the Youden index. The logistic regression model was performed identify independent risk factors for AL.

Results
Out of the 499 eligible patients, 40 experienced AL. Results of the ROC analyses showed that ΔALB displayed a significant predictive value for females, and the AUC value was 0.675 (P = 0.024), with a sensitivity of 93%. In male patients, the AUC was 0.575 (P = 0.22), but did not reach a significant level. In the multivariate analysis, ∆ALB ≥ 27.2% and low tumor location prove to be independent risk factors for AL in female patients.

Conclusions
The current study suggested that there may be a gender difference in the prediction of AL and ∆ ALB can serve as a potential predictive biomarker for AL in females. A cut-off value of the relative decline in serum albumin can help predict AL in female patients as early as postoperative day 2. Although our study needs further external validation, our findings may provide an earlier, easier and cheaper biomarker for the detection of AL.
Effect of filament types and loops number on the force degradation of elastomeric chains used for orthodontic treatment: an in-vitro study
Authors: Zheng Bowen , Al-Somairi Majedh Abdo Ali , Li Zhiyuan , Zhao Yang , Liu Yi 
Published: February 2023

Abstract
Background
In orthodontic treatment, closing spaces, specifically the extraction and scattered spaces of the anterior teeth, requires some auxiliary bias, such as an elastomeric chain. Many factors affect the mechanical properties of elastic chains. In this study, we investigated the relationship of the filament type, the number of loops, and the force degradation of elastomeric chains under thermal cycling conditions.

Methods
The orthogonal design included three filament types (i.e., close, medium, and long). Four, five, and six loops of each elastomeric chain were stretched to have an initial force of 250 g in an artificial saliva environment at 37 °C and thermocycling between 5 and 55 °C three times a day. The remaining force of the elastomeric chains was recorded at different time points (4 h, 24 h, 7 days, 14 days, 21 days, and 28 days), and the percentage of the remaining force was calculated.

Results
The force decreased significantly in the initial 4 h and degraded mostly within the first 24 h. In addition, the percentage of force degradation increased slightly between 1 and 28 days.

Conclusions
Under the same initial force, the longer the connecting body is, the fewer the number of loops and the greater the force degradation of the elastomeric chain are.