bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concomitant valgus hip osteotomy in operative fixation of displaced proximal femoral neck fractures
Authors: Khan Abdul Q. , Chowdhry Madhav , Sherwani Mohd K. A. , McPherson Edward J. 
Published: May 2023

AimsTotal hip arthroplasty (THA) is considered the preferred treatment for displaced proximal femoral neck fractures. However, in many countries this option is economically unviable. To improve outcomes in financially disadvantaged populations, we studied the technique of concomitant valgus hip osteotomy and operative fixation (VOOF). This prospective serial study compares two treatment groups: VOOF versus operative fixation alone with cannulated compression screws (CCSs).MethodsIn the first series, 98 hip fixation procedures were performed using CCS. After fluoroscopic reduction of the fracture, three CCSs were placed. In the second series, 105 VOOF procedures were performed using a closing wedge intertrochanteric osteotomy with a compression lag screw and lateral femoral plate. The alignment goal was to create a modified Pauwel’s fracture angle of 30°. After fluoroscopic reduction of fracture, lag screw was placed to achieve the calculated correction angle, followed by inter-trochanteric osteotomy and placement of barrel plate. Patients were followed for a minimum of two years.ResultsMean follow-up was 4.6 years (4.1 to 5.0) in the CCS group and 5.5 years (5.25 to 5.75) in the VOOF group. The mean Harris Hip Score at two-year follow-up was 83.85 in the CCS group versus 88.00 in the VOOF group (p < 0.001). At the latest follow-up, all-cause failure rate was 29.1% in the CCS group and 11.7% in the VOOF group (p = 0.003). The total cost of the VOOF technique was 7.2% of a THA, and total cost of the CCS technique was 6.3% of a THA.ConclusionThe VOOF technique decreased all-cause failure rate compared to CCS. The total cost of VOOF was 13.5% greater than CCS, but 92.8% less than a THA. Increased cost of VOOF was considered acceptable to all patients in this series. VOOF technique provides a reasonable alternative to THA in patients who cannot afford a THA procedure.Cite this article: Bone Jt Open 2023;4(5):329–337.
Ice Nucleation Active bacteria in Mount Lawu forest, Indonesia: 3. Isolation and estimation of bacterial populations on bryophyte
Authors: LATIFAH NOVI HIDAYATUL , SUSILOWATI ARI , SURATMAN SURATMAN 
Published: May 2023

Abstract. Latifah NH, Susilowati A, Suratman. 2018. Ice Nucleation Active bacteria in Mount Lawu forest, Indonesia: 3. Isolation and estimation of bacterial populations on bryophyte. Asian J For 2: 67-75. This study aimed to isolate and estimate the Ice Nucleation Active (INA) bacteria population on bryophyte from the trekking route of Cemoro Sewu, Mount Lawu, Indonesia. Bryophyte samples were taken at three different altitudes, i.e., 2,000, 2,300, and 2,500 m above sea level (asl). Isolation of INA bacteria was carried out by the method of spread plate on King's B and nutrient agar plus 2.5% glycerol (NAG) medium. Bryophyte was identified by referring to the literature of Sutama (1995), Hasan and Ariyanti (2004), Ignatova and Samkova (2006), and Damayanti (2006). Ice nucleation activity was determined by the multiple-tube test method. The bacterial suspension tube was put into the circulating alcohol bath at a temperature of -10°C for 5 minutes. The number of INA bacteria on the bryophyte was estimated with the nucleation multiple tube method. The number (cell/g) of INA bacteria from the fresh weight of bryophyte was estimated based on the Most Probable Number (MPN) tables according to the formula of Thomas's 333 series. INA bacteria were identified through morphological and biochemical characters. Independent Sample T-Test analyzed the population of INA bacteria on terrestrial and epiphytes bryophytes with a significance of 5%. The results showed that 7 INA bacteria were isolated from the bryophyte Campylopus umbellatus (Arn.) Paris (Leucobryaceae, Musci). The population of INA bacteria in terrestrial bryophytes at each altitude were greater with 346 cell/g, 86 cell/g, and 396 cell/g, respectively, than that in epiphytes bryophyte with 50 cell/g, 50 cell/g, 176 cell/g, respectively.
Utilization of a novel mobile application, “HBB Prompt”, to reduce Helping Babies Breathe skills decay
Authors: Chan Natalie Hoi-Man , Merali Hasan S. , Mistry Niraj , Kealey Ryan , Campbell Douglas M. , Morris Shaun K. , Data Santorino 
Published: May 2023

Background
Helping Babies Breathe (HBB) is a newborn resuscitation training program designed to reduce neonatal mortality in low- and middle-income countries. However, skills decay after initial training is a significant barrier to sustained impact.

Objective
To test whether a mobile app, HBB Prompt, developed with user-centred design, helps improve skills and knowledge retention after HBB training.

Methods
HBB Prompt was created during Phase 1 of this study with input from HBB facilitators and providers from Southwestern Uganda recruited from a national HBB provider registry. During Phase 2, healthcare workers (HCWs) in two community hospitals received HBB training. One hospital was randomly assigned as the intervention hospital, where trained HCWs had access to HBB Prompt, and the other served as control without HBB Prompt (NCT03577054). Participants were evaluated using the HBB 2.0 knowledge check and Objective Structured Clinical Exam, version B (OSCE B) immediately before and after training, and 6 months post-training. The primary outcome was difference in OSCE B scores immediately after training and 6 months post-training.

Results
Twenty-nine HCWs were trained in HBB (17 in intervention, 12 in control). At 6 months, 10 HCW were evaluated in intervention and 7 in control. In intervention and control respectively, the median OSCE B scores were: 7 vs. 9 immediately before training, 17 vs. 21 immediately after training, and 12 vs. 13 at 6 months after training. Six months after training, the median difference in OSCE B scores was -3 (IQR -5 to -1) in intervention and -8 (IQR -11 to -6) in control (p = 0.02).

Conclusion
HBB Prompt, a mobile app created by user-centred design, improved retention of HBB skills at 6 months. However, skills decay remained high 6 months after training. Continued adaptation of HBB Prompt may further improve maintenance of HBB skills.
Muscle magnetic resonance characterization of STIM1 tubular aggregate myopathy using unsupervised learning
Authors: Lupi Amalia , Spolaor Simone , Favero Alessandro , Bello Luca , Stramare Roberto , Pegoraro Elena , Nobile Marco Salvatore 
Published: May 2023

Purpose
Congenital myopathies are a heterogeneous group of diseases affecting the skeletal muscles and characterized by high clinical, genetic, and histological variability. Magnetic Resonance (MR) is a valuable tool for the assessment of involved muscles (i.e., fatty replacement and oedema) and disease progression. Machine Learning is becoming increasingly applied for diagnostic purposes, but to our knowledge, Self-Organizing Maps (SOMs) have never been used for the identification of the patterns in these diseases. The aim of this study is to evaluate if SOMs may discriminate between muscles with fatty replacement (S), oedema (E) or neither (N).

Methods
MR studies of a family affected by tubular aggregates myopathy (TAM) with the histologically proven autosomal dominant mutation of the STIM1 gene, were examined: for each patient, in two MR assessments (i.e., t0 and t1, the latter after 5 years), fifty-three muscles were evaluated for muscular fatty replacement on the T1w images, and for oedema on the STIR images, for reference. Sixty radiomic features were collected from each muscle at t0 and t1 MR assessment using 3DSlicer software, in order to obtain data from images. A SOM was created to analyze all datasets using three clusters (i.e., 0, 1 and 2) and results were compared with radiological evaluation.

Results
Six patients with TAM STIM1-mutation were included. At t0 MR assessments, all patients showed widespread fatty replacement that intensifies at t1, while oedema mainly affected the muscles of the legs and appears stable at follow-up. All muscles with oedema showed fatty replacement, too. At t0 SOM grid clustering shows almost all N muscles in Cluster 0 and most of the E muscles in Cluster 1; at t1 almost all E muscles appear in Cluster 1.

Conclusion
Our unsupervised learning model appears to be able to recognize muscles altered by the presence of edema and fatty replacement.
ANTES FOSSE UMA MOSCA NA SOPA, SÔ! MURMÚRIOS DE DONA ZIZI EM TEMPOS DE PANDEMIA
Authors: Costa Oliveira Ananias , Salete Batista Freitag Maria , Santos Fonseca Viviane , Gomes de Oliveira Leandro 
Published: May 2023

RESUMO
Dilema: Em cenários de grandes incertezas decorrentes da pandemia, ainda é viável manter a tradição de apostar somente no atendimento presencial ou é hora de aderir ao sistema de delivery? Somente isso é suficiente?
Objetivo educacional: Este caso para ensino visa propiciar aos discentes vivências de situações condizentes com a realidade organizacional e o desenvolvimento da capacidade de tomada de decisão, ao analisar o dilema de implantação ou não de um sistema alternativo de atendimento, dadas as medidas restritivas de funcionamento decorrentes da pandemia da COVID-19.
Contextualização: O advento da COVID-19 ocasionou mudanças drásticas no cotidiano dos empreendimentos brasileiros, inclusive no setor de Alimentação Fora do Lar (AFL). Dona Zizi e seu filho Pedro, donos de um restaurante de comida caseira no município de Goiânia, precisaram reinventar o formato do atendimento ao cliente no período pandêmico, com intuído de evitar a perda da clientela, a demissão em massa de colaboradores e o fechamento do estabelecimento.
Tema principal: Tomada de decisão em tempos de pandemia.
Público: O caso pode ser aplicado a estudantes dos cursos de graduação em administração, nas disciplinas de marketing, empreendedorismo e planejamento estratégico.
Originalidade/valor: Os discentes irão assumir o papel do gestor e tomar decisões sobre um leque de inquietações e problemas que surgiram no cotidiano do Gastrô Mineiro, no período da pandemia. Este caso de ensino resgata conceitos teóricos básicos sobre Mix de Marketing, Cinco Forças de Porter, Teoria da Decisão e Análise da Concorrência, com objetivo de traçar estratégias que atendam as contingências decorrentes da pandemia e ampliar a proposta de valor do restaurante em estudo.
EDUCOMUNICAÇÃO E AS PRÁTICAS DE EXTENSÃO NA EDUCAÇÃO DO CAMPO EM ASSENTAMENTOS RURAIS DO MUNICÍPIO DE TUPANCIRETÃ/RS
Authors: CAMILLO Cíntia Moralles , MEDEIROS Liziany Muller 
Published: May 2023

A educomunicação permite novos tipos de aprendizagem, formais ou informais,com viés mais democrático, igualitário e menos hierarquizado, atendendo à pluralidade e à diversidade cultural. Neste sentido, desenvolveu-se um projeto com finalidade de promover a educomunicação como prática extensionista na Educação do Campo nos assentamentos rurais no município de Tupanciretã no estado do Rio Grande do Sul - Brasil, por meio da produção de um vídeo. Para tanto, utilizou-se a linguagem cinematográfica com base na educação pela autoria e pelo protagonismo como forma de promover ações criativas e integradoras, possibilitando mudanças nas atitudes e nos valores dos sujeitos do campo em relação à conservação dos seus recursos naturais, que incluem tanto variáveis econômicas e sociais como variáveis culturais, políticas e éticas da sustentabilidade.
POLÍTICAS PÚBLICAS QUE SUBSIDIAM A INOVAÇÃO NO BRASIL
Authors: PANISSON César , WILLERDING Inara Antunes Vieira , LAPOLLI Édis Mafra 
Published: May 2023

O novo modelo econômico, baseado no conhecimento, traz a inovaçãocomo principal aspecto de valor para o desenvolvimento social e econômico de uma nação ou região. Nesse sentido, os Sistemas Nacionais e Regionais de Inovação buscam constituir uma estrutura com mecanismos que contribuem para o desenvolvimento da inovação, por meio de políticas públicas de fomento e incentivo, além de integrar os agentes públicos e privados. Dessa forma, o Estado tem importante papel no desenvolvimento de Empresas de Base Tecnológica, que por sua vez tem a inovação como principal fator estratégico. Este estudo aborda as políticas públicas brasileiras que subsidiam a inovação por meio de incentivos e fomento às Empresas de Base Tecnológicas. Para isso, realizou-se um estudo qualitativo de cunho bibliográfico, exploratório e descritivo. Como resultado pode se verificar que o Sistema Nacional brasileiro possui uma diversidade de mecanismos que subsidiam a inovação, porémainda carece de maior dinamismo para seu amadurecimento e eficiência de suas políticas.
PENENTUAN POTENSI KAWASAN PERUNTUKAN INDUSTRI MENGGUNAKAN ANALYTICAL HIERARCHY PROCESS (AHP) DAN SISTEM INFORMASI GEOGRAFIS DI KABUPATEN JEPARA
Authors: Labib Muhammad Faishal , Awaluddin Moehammad , Wahyuddin Yasser 
Published: May 2023

Kabupaten Jepara mengalami peningkatan pertumbuhan industri ditinjau dari peningkatan investasi Penanaman Modal Asing (PMA). Penentuan yang berpotensi sebagai pengembangan industri dibutuhkan untuk mendorong pertumbuhan sektor industri agar lebih terarah dan terpadu. Metode Sistem Informasi Geografis (SIG) merupakan metode yang memanfaatkan aspek parameter spasial yang digunakan dalam menentukan lokasi potensial untuk pengembangan industri di Kabupaten Jepara. Terdapat sepuluh parameter spasial dalam penelitian ini yang digunakan dalam penentuan kawasan peruntukan industri di antaranya adalah kemiringan lereng, jenis tanah, penggunaan lahan, curah hujan, jarak ke jalan utama, jarak ke jaringan listrik, jarak ke jaringan sungai, jarak ke fasilitas umum, jarak ke pemukiman dan jarak dari pusat kota. Data tersebut kemudian dilakukan pembobotan dengan metode Analytical Hierarchy Process (AHP). Metode AHP digunakan untuk mengetahui besar bobot yang mempengaruhi pada masing-masing parameter. Hasil penelitian ini yaitu peta potensial lahan kawasan peruntukan industri. Berdasarkan hasil pembobotan diperoleh lima kelas klasifikasi tanah yaitu sangat sesuai (S1) sebanyak 1,027 %, sesuai (S2) sebesar 14,402 %, cukup sesuai (S3) sebesar 33,472%, kurang sesuai (N1) sebesar 37,624 % serta tidak sesuai sebesar (N2) 13,475 %. Hasil dari intersect peta potensi lahan KPI dengan RTRW diperoleh wilayah yang sangat sesuai sebesar 31.655596 ha. Kata Kunci: AHP, SIG, Potensi Lahan Industri
Inspiratory pressure waveform influences time to failure, respiratory muscle fatigue, and metabolism during resistive breathing
Authors: Poulsen Mathias Krogh , Rees Stephen E. , Hansen John , Stevenson Andrew J. T. , Kjærgaard Søren , Volta Carlo A. , Spadaro Savino , Karbing Dan S. 
Published: May 2023

AbstractIncreased ventilatory work beyond working capacity of the respiratory muscles can induce fatigue, resulting in limited respiratory muscle endurance (Tlim). Previous resistive breathing investigations all applied square wave inspiratory pressure as fatigue‐inducing pattern. Spontaneous breathing pressure pattern more closely approximate a triangle waveform. This study aimed at comparing Tlim, maximal inspiratory pressure (PImax), and metabolism between square and triangle wave breathing. Eight healthy subjects (Wei = 76 ± 10 kg, H = 181 ± 7.9 cm, age = 33.5 ± 4.8 years, sex [F/M] = 1/7) completed the study, comprising two randomized matched load resistive breathing trials with square and triangle wave inspiratory pressure waveform. Tlim decreased with a mean difference of 8 ± 7.2 min (p = 0.01) between square and triangle wave breathing. PImax was reduced following square wave (p = 0.04) but not for triangle wave breathing (p = 0.88). Higher VO2 was observed in the beginning and end for the triangle wave breathing compared with the square wave breathing (p = 0.036 and p = 0.048). Despite higher metabolism, Tlim was significantly longer in triangle wave breathing compared with square wave breathing, showing that the pressure waveform has an impact on the function and endurance of the respiratory muscles.
Voltage sensor current, SR Ca2+ release, and Ca2+ channel current during trains of action potential‐like depolarizations of skeletal muscle fibers
Authors: Bibollet Hugo , Nguyen Elton L. , Miranda Daniel R. , Ward Christopher W. , Voss Andrew A. , Schneider Martin F. , Hernández‐Ochoa Erick O. 
Published: May 2023

AbstractIn skeletal muscle, CaV1.1 serves as the voltage sensor for both excitation‐contraction coupling (ECC) and L‐type Ca2+ channel activation. We have recently adapted the technique of action potential (AP) voltage clamp (APVC) to monitor the current generated by the movement of intramembrane voltage sensors (IQ) during single imposed transverse tubular AP‐like depolarization waveforms (IQAP). We now extend this procedure to monitoring IQAP, and Ca2+ currents during trains of tubular AP‐like waveforms in adult murine skeletal muscle fibers, and compare them with the trajectories of APs and AP‐induced Ca2+ release measured in other fibers using field stimulation and optical probes. The AP waveform remains relatively constant during brief trains (<1 sec) for propagating APs in non‐V clamped fibers. Trains of 10 AP‐like depolarizations at 10 Hz (900 ms), 50 Hz (180 ms), or 100 Hz (90 ms) did not alter IQAP amplitude or kinetics, consistent with previous findings in isolated muscle fibers where negligible charge immobilization occurred during 100 ms step depolarizations. Using field stimulation, Ca2+ release did exhibit a considerable decline from pulse to pulse during the train, also consistent with previous findings, indicating that the decline of Ca2+ release during a short train of APs is not correlated to modification of charge movement. Ca2+ currents during single or 10 Hz trains of AP‐like depolarizations were hardly detectable, were minimal during 50 Hz trains, and became more evident during 100 Hz trains in some fibers. Our results verify predictions on the behavior of the ECC machinery in response to AP‐like depolarizations and provide a direct demonstration that Ca2+ currents elicited by single AP‐like waveforms are negligible, but can become more prominent in some fibers during short high‐frequency train stimulation that elicits maximal isometric force.
Cloud-based evaluation platform for software-defined manufacturing
Authors: Neubauer Michael , Reiff Colin , Walker Moritz , Oechsle Stefan , Lechler Armin , Verl Alexander 
Published: May 2023

Abstract
Software-Defined Manufacturing (SDM) is a new paradigm for how to manufacture in the Industry 4.0 factory of the future. The approach requires a fundamental change in thinking and reinvention of central business models in production technology. This paper discusses the main challenges on the way to a software-defined factory of the future and illustrates possible solutions. An exemplary future factory is presented, in which the validation of the solutions is carried out. For this purpose, cloud-based Computerized Numerical Control (CNC) is considered as use case. Experimental results demonstrate the proof of concept and show the potential for further applications.
Silica and kaolin reinforced aluminum matrix composite for heat storage
Authors: Ogunrinola Iyanuoluwa , Akinyemi Marvel , Aizebeokhai Ahzegbobor , Sule Rasidi , Sanni Samuel , Boyo Henry , Omeje Maxwell , Babalola Philip 
Published: May 2023

Abstract
This study used aluminum scraps to produce a secondary aluminum metal matrix for heat storage analyses. Silica and kaolin reinforced aluminum metal matrix composites were successfully produced via stir casting. The X-ray diffraction (XRD) and scanning electron microscopy (SEM) were employed for phase and microstructure characterization. XRD revealed alumina (corundum), aluminum and kyanite phases while SEM indicated pores in the composites. Density, average specific heat (from 30 to 200°C), thermal conductivity, and hardness tests were carried out. Total heat energy stored per kg, from 30 to 200°C, was obtained. The inclusion of 7.5 and 15 wt% kaolin increased the specific heat of the matrix from 474.3 to 564.57 J·kg−1·°C−1 and 474.3 to 679.03 J·kg−1·°C−1, respectively. Likewise, adding 7.5 and 15 wt% silica sand increased the thermal conductivity of the matrix from 154.99 to 175.62 W·m−1·°C−1 and 154.99 W·m−1·°C−1 to 181.38 W·m−1·°C−1, respectively. The addition of 7.5 wt% silica sand and 7.5 and 15 wt% kaolin increased the hardness value of the matrix from 72.11 to 73.11 HB, 72.11 to 81.38 HB, and 72.11 to 82 HB, respectively. Hardness of the composites reinforced with kaolin is higher than that of the composites reinforced with silica sand. This is attributed to the higher molecular weight of kaolin. Significant increase in specific heat and thermal conductivity was achieved.
Denoting Concepts and Ontology in Russell's Principles of Mathematics
Authors: Cohen Wouter Adriaan 
Published: May 2023

Bertrand Russell’s Principles of Mathematics (1903) gives rise to several interpretational challenges, especially concerning the theory of denoting concepts. Only relatively recently, for instance, has it been properly realised that Russell accepted denoting concepts that do not denote anything. Such empty denoting concepts are sometimes thought to enable Russell, whether he was aware of it or not, to avoid commitment to some of the problematic non-existent entities he seems to accept, such as the Homeric gods and chimeras. In this paper, I argue first that the theory of denoting concepts in Principles of Mathematics has been generally misunderstood. According to the interpretation I defend, if a denoting concept shifts what a proposition is about, then the aggregate of the denoted terms will also be a constituent of the proposition. I then show that Russell therefore could not have avoided commitment to the Homeric gods and chimeras by appealing to empty denoting concepts. Finally, I develop what I think is the best understanding of the ontology of Principles of Mathematics by interpreting some difficult passages.
Coming to America: Carnap, Reichenbach and the Great Intellectual Migration. Part I: Rudolf Carnap
Authors: Verhaegh Sander 
Published: May 2023

In the years before the Second World War, Rudolf Carnap and Hans Reichenbach emigrated to the United States, escaping the quickly deteriorating political situation on the continent. Once in the U. S., the two significantly changed the American philosophical climate. This two-part paper reconstructs Carnap’s and Reichenbach’s surprisingly numerous interactions with American academics in the decades before their move in order to explain the impact of their arrival in the late 1930s. Building on archival material of several key players and institutions, I take some first steps toward answering the question why logical empiricism became so successful in the United States after the War. This first part reconstructs Carnap’s development between 1923, when he first visited New York, and 1936, when he was offered a position at the University of Chicago. I describe Carnap’s first substantive contacts with American philosophers as well as the events leading up to his decision to emigrate. In addition, I argue that some of Carnap’s work from the mid-1930s—in particular “Testability and Meaning”—can be better understood if we take into account (1) his attempts to correct the American narrative about logical positivism and (2) his increasingly desperate efforts to find a position in the United States.