bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Rural Residence With Surgical Outcomes Among Infants at US Children’s Hospitals
Authors: Georgeades Christina , Vacek Jonathan , Thurm Cary , Hall Matt , Rangel Shawn , Minneci Peter C. , Oldham Keith , Van Arendonk Kyle J. 
Published: July 2023

OBJECTIVES
Disparities in pediatric health outcomes are widespread. It is unclear whether rurality negatively impacts outcomes of infants with surgical congenital diseases. This study compared outcomes of rural versus urban infants requiring complex surgical care at children’s hospitals in the United States.

METHODS
Rural and urban infants (aged &lt;1 year) receiving surgical care at children’s hospitals from 2016 to 2019 for esophageal atresia, gastroschisis, Hirschsprung’s disease, anorectal malformation, and congenital diaphragmatic hernia were compared over a 1-year postoperative period using the Pediatric Health Information System. Generalized linear mixed effects models compared outcomes of rural and urban infants.

RESULTS
Among 5732 infants, 20.2% lived in rural areas. Rural infants were more frequently white, lived farther from the hospital, and lived in areas with lower median household income compared with urban infants (all P &lt; .001). Rural infants with anorectal malformation and gastroschisis had lower adjusted hospital days over 1 year; rural infants with esophageal atresia had higher adjusted odds of 30-day hospital readmission. Adjusted mortality, hospital days, and readmissions were otherwise similar between the 2 groups. Outcomes remained similar when comparing urban infants to rural infant subgroups with the longest hospital travel distance (≥60 miles) and lowest median household income (&lt;$35 000).

CONCLUSIONS
Despite longer travel distances and lower financial resources, rural infants with congenital anomalies have similar postoperative outcomes to urban infants when treated at children’s hospitals. Future work is needed to examine outcomes for infants treated outside children’s hospitals and to determine whether efforts are necessary to increase access to children’s hospitals.
Una imagen en blanco. Percepción y tiempo en la fotografía de Hiroshi Sugimoto.
Authors: Jiménez-Donaire Martínez Salvador 
Published: July 2023

La obra de Hiroshi Sugimoto abarca más de cuatro décadas y el artista japonés se ha convertido en uno de los creadores más aclamados de su generación. Su práctica artística se cimienta sobre nociones como el tiempo, la memoria o la transitoriedad. En este texto examinamos las series Theaters y Seascapes, dos de los proyectos más celebrados del artista, en los que Sugimoto ofrece un registro visual de la duración. Con un enfoque conceptual y a través de una metodología paciente, basada en largos tiempos de exposición y un meticuloso proceso de revelado analógico, Sugimoto levanta cuestiones radicales en torno al binomio tiempo-fotografía. En el presente texto analizaremos cómo las estrategias de ralentización y dilación propuestas por Sugimoto alteran nuestra percepción y experiencia temporal. Para ello, revisaremos los vínculos de su trabajo con teorías sobre el Slow Art, categoría artística propuesta por Arden Reed, y nos acercaremos, de la mano de Juan Martín Prada, a la obra de Sugimoto en clave de contraimagen para demostrar que su fotografía nos brinda, destilada, una oportunidad para la contemplación y el descanso perceptivo: una imagen-tiempo.
Improving the model of payment for medical care for chronic viral hepatitis C in the framework of the implementation of the Program of State Guarantees of Free Provision of Medical Care to Citizens for 2023 and for the planned period of 2024–2025
Authors: Omelyanovskiy V. V. , Zheleznyakova I. A. , Zuev A. V. , Plakhotnik O. S. , Volkova O. A. , Davydova L. M. , Trifonova G. V. , Semakova E. V. , Prokhorovich E. A. , Volkova A. S. 
Published: July 2023

Background. In 2021, new clinical guidelines for the treatment of chronic hepatitis C virus (HCV) in adults were published that did not contain interferon drug therapy regimens. Current therapy of chronic HCV is based on modern drugs of direct-acting antivirals (DAA). In this regard, the model of diagnosis-related groups (DRG) with the use of interferon-containing drugs as etiotropic therapy, which has been in effect until now, has lost its relevance and cannot be used to pay for cases of medical care for chronic HCV within the framework of the Program of State Guarantees of Free Medical Care to Citizens for 2023 and for the planning period of 2024–2025 (PSG). Objective: to improve the DRG model to pay for medical care for chronic HCV in a day hospital based on current clinical recommendations.Material and methods. Regulatory legal documents on the subject of the study, proposals and expert opinions of specialists, as well as feedback from public organizations, including patients, regarding the payment of medical care for chronic HCV, sent as part of a public discussion of the draft PSG, were studied. For the calculations were used: the current version of the clinical recommendations "Chronic viral hepatitis C"; impersonal personalized information of the database of registers of bills for payment for medical care for 2020–2021; the state register of manufacturers' maximum selling prices for medicines included in the list of vital and essential drugs.Results. A DRG model was developed to pay for medical care during drug therapy of chronic HCV, including for children. When calculating the model, the cost of medicines, patient days and the principles of accounting for the duration of hospitalization were updated.Conclusion. The developed DRG model to pay for medical care for chronic HCV in a day hospital with the use of drug therapy regimens with DAA recommended by clinical guidelines, including for children with HCV, contributes to improving the effectiveness of the system of payment for medical care provided as part of the implementation of the PSG and accessibility of medical care for this contingent of patients.
Comparative pharmacoeconomic analysis of follitropin delta application for superovulation induction during artificial insemination
Authors: Krysanov I. S. , Krysanova V. S. , Ermakova V. Yu. 
Published: July 2023

Objective: to conduct a comparative pharmacoeconomic analysis of using follitropin delta for controlled ovarian stimulation in adult women to induce the growth of multiple follicles during cycles of assisted reproductive technology (ART) programs – in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).Material and methods. The available literature was searched for data on clinical effectiveness and safety of follitropin delta and follitropin alfa. Two large studies were found – ESTHER-1 and ESTHER-2 as well as their combined analysis, based on which a decision tree model was built. Considering the presence of a significant difference between safety profile of analyzed follitropins (the frequency of preventive medical interventions in relation to the development of ovarian hyperstimulation syndrome (OHSS)), the cost-effectiveness analysis was used. The cost analysis included only direct medical costs: drugs (treated separately), ART program cycle, relief of complications. As part of the budget impact analysis (BIA), several options for managing patients with infertility were considered: current practice (in 100% of cases, the use of follitropin alfa), simulated practice (transfer of 50% of patients to follitropin delta). Time horizon was IVF/ICSI cycle 1 within ART program for cost-effectiveness analysis, and 1 year for BIA. Results. Despite the fact that the use of follitropin delta is associated with a higher level of drug costs compared to follitropin alfa, the costs of IVF/ICSI cycles within ART programs and the relief of complications are lower with the use of follitropin delta. The total costs for the Cycle 1 amounted to 132,123.99 rubles with the use of follitropin delta, and 133,392.19 rubles with the use of follitropin alfa. The total costs for three cycles were 200,952.17 rubles with the use of follitropin delta, and 204,296.62 rubles with the use of follitropin alfa (2% difference). The costs per 1 case of no medical interventions due to OHSS for follitropin delta amounted to 135,234.38 rubles, which is 3.2% less compared to the same indicator for follitropin alfa (139,677.69 rubles). BIA demonstrated that the use of follitropin delta will reduce the economic burden on the healthcare system by 49.5 million rubles within 1 year.Conclusion. According to the results of the study, the use of follitropin delta individual dosing regimen for controlled ovarian stimulation in adult patients as part of IVF/ICSI cycles within ART programs is effective and economically justified approach to organizing medical care for adult patients with infertility in Russia.
Caregiving Burden in Family Caregivers Of Patients With Schizophrenia Post-Pasung in Jember
Authors: Mata Lusi Padma Sulistianingsih , Kusumastuti Inke , Astuti Ida Sri Surani Wiji , Rachmania Sheilla 
Published: July 2023

Pasung (restrain) towards people with schizophrenia has yet to recede from being a complex problem in Jember, East Java. One of many aspects of pasung that has not been widely studied is the caregiving burden in the post-pasung period. This research aimed to comprehend the meaning-making of the caregiving phenomenon as experienced by the families of people with schizophrenia during the patients’ post-pasung period in Jember. This research utilizing the interpretive phenomenological analysis (IPA) recruited 11 participants (7 caregivers of people with schizophrenia and 4 community mental health nurses) who were purposively sampled and underwent semistructured interviews from November to December 2019. Two themes emerged in this study namely the experience of the post-pasung caregivers and triangulation with the community mental health nurses which consisted of 8 and 3 subthemes, respectively. Post-pasung caregiving burden experienced by families in this study consisted of subjective, objective, and iatrogenic burdens. Compared with the pasung period, the burden was lighter both for objective and subjective caregiving burden. The most dominating burden is the subjective burdens including apprehensiveness, stigma from the family and the society, and advice from external parties that were against the process of recovery and the objective burden came in the form of the caregiver’s significant health problems. Caregivers made various efforts supported by the provision of accessible and holistic health services as well as interdisciplinary coordination to ease the burden. This study indicates the diversity of the caregiving burden of post-pasung people with schizophrenia. This diversity suggests that interventions aimed at lightening the burden should be carefully selected based on the actual needs of the caregivers.
Keywords : caregiving burden, caregivers, pasung, schizophrenia
Insights from leaders on effectively addressing overweight and obesity in the Thai community
Authors: Piyakong Duangporn , Apiratanawong Sangduan , Suasing Chanikan 
Published: July 2023

Introduction: Effective management of health care system at the district level through an important health project can improve health and quality of life of people in the district. Key factors to drive a successful project are important. The purpose of this study was to explore perspectives of leaders managing the health care system at a district level on improving health problems of people in a community through a project according to preventing and solving overweight and obesity issues.
Methods: The participants of this qualitative study consisted of nine district health board committees, ten members of the district health system startup team and twenty-four village health system managers. Data was collected by using focus group interviews, observation and documents analysis, also analyzing data by summarizing and categorizing the data of main points.
Results: The study results indicated that managing successful health problems at the district level needed: 1) creating clear and equal understanding, 2) having precious community capital and 4) integrating effective incentives for people in the community.
Conclusion: The findings of the study can be used as a guideline for managing the health care system in a district level through a project for the development of health issues and the quality of life among people in a community. This successful health system management might be able to help develop the sustainability of public health care at the district level.
Anatomic Assessment of L1-S1 Neuroforaminal Dimensions Using Computed Tomography
Authors: Harianja Gideon , Razzouk Jacob , Lindsey Wyatt , Urbina Bryan , Cabrera Andrew , Thomas Luke , Bouterse Alex , Wycliffe Nathaniel , Cheng Wayne , Danisa Olumide 
Published: July 2023

Background:
Although the radiographic parameters for diagnosing central lumbar canal stenosis are well described, parameters for the diagnosis of neuroforaminal stenosis (NFS) are less well defined. Previous studies have used magnetic resonance imaging (MRI) and radiography to describe neuroforaminal dimensions (NFDs). Those methods, however, have limitations that may substantially distort measurements. Existing literature on the use of computed tomography (CT) to investigate normal NFDs is limited.

Methods:
This anatomic assessment evaluated CT imaging of 300 female and 300 male subjects between 18 and 35 years of age to determine normal NFDs, specifically the sagittal anteroposterior width, axial anteroposterior width, craniocaudal height, and area. Statistical analyses were performed to assess differences in NFDs according to variables including sex, age, height, weight, body mass index, and ethnicity.

Results:
Overall, mean NFDs were 9.08 mm for sagittal anteroposterior width, 8.93 mm for axial anteroposterior width, 17.46 mm for craniocaudal height, and 134.78 mm2 for area (n = 6,000 measurements each). Male subjects had larger NFDs than females at multiple levels. Both Caucasian and Asian subjects had larger NFDs than African-American subjects at multiple levels. There were no associations between foraminal dimensions and anthropometric factors.

Conclusions:
This study describes CT-based L1-S1 NFDs in young, healthy patients who presented with reasons other than back pain or pathology affecting the neuroforamen. Dimensions were influenced by sex and ethnicity but were not influenced by anthropometric factors.

Level of Evidence:
Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Women’s experiences of the indirect impacts of the COVID-19 pandemic in high-income countries: a qualitative evidence synthesis
Authors: Tan Annie , Blair Amanda , Homer Caroline SE. , Digby Robin , Vogel Joshua P. , Bucknall Tracey 
Published: July 2023

Abstract
Background
Pregnant and postpartum women’s experiences of the COVID-19 pandemic, as well as the impact of COVID-19 on perinatal health, has been well-documented across high-income countries. Increased anxiety and fear, isolation, as well as a disrupted pregnancy and postnatal period are widely described in many studies. The aim of this study was to explore, describe and synthesise studies that addressed the experiences of pregnant and postpartum women in high-income countries during the first two years of the pandemic.
Methods
A qualitative evidence synthesis (QES) was undertaken. Five electronic databases were searched from January 2020 – January 2022. Primary qualitative studies of women’s experiences during the pandemic were included. Two independent reviewers extracted the data using a thematic synthesis approach and NVivo 20 software. The GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative research) was used to assess confidence in review findings.
Results
Sixty-eight studies were eligible and subjected to a sampling framework to ensure data richness. In total, 36 sampled studies contributed to the development of themes, sub-themes and review findings. There were six over-arching themes: (1) dealing with public health restrictions; (2) navigating changing health policies; (3) adapting to alternative ways of receiving social support; (4) dealing with impacts on their own mental health; (5) managing the new and changing information; and (6) being resilient and optimistic. Seventeen review findings were developed under these themes with high to moderate confidence according to the GRADE-CERQual assessment.
Conclusions
This review has provided a cohesive and transparent documentation of pregnant and postpartum women’s experiences during the first two years of the COVID-19 pandemic. The findings from the QES offer different strategies for practice and policy makers to better support women, babies and their families in future emergency responses.
Study on crystal structure, thermal property, and nuclear magnetic resonance spin-lattice relaxation times of organic-inorganic hybrid [NH 3 (CH 2 ) 6 NH 3 ]ZnCl 4
Authors: Lim Ae Ran , Kim Sun Ha 
Published: July 2023

Abstract
Organic-inorganic hybrid compounds have recently gained significant attention in recent years due to their diverse applications. Herein, [NH3(CH2)6NH3]ZnCl4 crystals were grown, and their triclinic structure, phase transition temperature (TC = 408 K), and high thermal stability (Td =584 K) was determined using X-ray diffraction (XRD), differential scanning calorimetry, and thermogravimetry measurements. By analyzing the chemical in response to temperature changes, we observed that the coordination geometry around 1H and 13C were highly symmetric below TC, whereas their symmetry was lowered above TC. The change of N‒H∙∙∙Cl hydrogen bond from XRD results and the change of 14N NMR chemical shifts was due to the changes to the coordination geometry of Cl around Zn2+ in the ZnCl4 anion. The activation energy of 1H was three times greater than that of 13C, and this result indicates that the energy transfer of 13C was easier than those of 1H. We compared the results for [NH3(CH2)nNH3]ZnCl4 (n=6) studied here with those for n=2, 3, 4, and 5 obtained from previous studies. The characteristics of the length of CH2 and even–odd number of carbons in the methylene chain are expected to be used for potential applications in the near future.
Prospective evaluation of cardiovascular risk and mortality in patients with psoriasis: A population-base study
Authors: Chen Qitao , Kan Junyan , Tao Qiuwei , Wu Lida , Wang Dongchen , Jiang Zihao , Du Xufeng , Gu Yue , Gu Yong , Chen Shaoliang 
Published: July 2023

Abstract
Background
The association between psoriasis and cardiovascular disease (CVD) has long been discussed and continually refined. However, there is currently a lack of prospective studies on the cardiovascular risk attributed to psoriasis in the general population.
Methods
Representative adult participants were selected from the National Health and Nutrition Examination Survey (NHANES). Risks of cardiovascular symptoms and diseases prevalence were evaluated between participants with and without psoriasis. The hazards for all-cause mortality and CVD mortality were stratified by psoriasis status. Mediation analysis was then conducted to identify potential mediators between psoriasis and cardiac death.
Results
Overall, 19,741 participants were included in the current study, 542 (2.7%) had psoriasis and 19,199 (97.3%) did not have psoriasis. After adjusting for known CVD risk factors, odds for hypertension (OR = 1.37, 95% CI: 1.13-1.66, p= 0.001), hypercholesterolemia (OR = 1.37, 95% CI: 1.13-1.64, p < 0.001) and angina pectoris (OR = 1.74, 95% CI: 1.11-2.60, p = 0.011) were higher in psoriasis patients. Compared with participants without psoriasis, moderate/severe but not mild patients showed significantly higher CVD mortality (HR = 2.55, 95% CI: 1.27-5.15, p = 0.009). This result was supported by subgroup analyses. Mediation analysis further suggested that the direct effect of moderate/severe psoriasis on CVD mortality accounted for 81.4% (65.8%-97.1%). Besides, the indirect effect might derive from disturbance of serum albumin, urea nitrogen and uric acid.
Conclusions
Moderate-to-severe psoriasis is an independent risk factor for cardiovascular disease, making it necessary to regularly conduct cardiovascular disease-related examinations for patients with higher severity of psoriasis in clinical settings.
Association of gestational weeks, initial maternal perception of fetal movement, and individual interoceptive differences
Authors: Furusho Miku , Noda Minami , Sato Yoko , Suetsugu Yoshiko , Morokuma Seiichi 
Published: July 2023

Abstract
The gestational week when the mother first becomes aware of fetal movement varies with unknown factors causing them. Interoception refers to the conscious awareness of homeostasis in the body. Considering that awareness of fetal movement is a part of interoception in pregnant women, the variation in the timing of initial detection of fetal movement may reflect individual interoceptive differences. This study aimed to clarify the association between the gestational week at the first awareness of fetal movements and interoception in pregnant women. We found a significant association between the gestational week at the first fetal movement awareness and interoception as measured by performing the heartbeat counting task.
Comparison of the degree of patient satisfaction between transoral thyroidectomy and open thyroidectomy: A survey-based study
Authors: Lee Jun Sung , Oh Jooyoung , Bae Jayyoung , Lee Jin Seok , Yun Hyeok Jun , Kim Seok-Mo , Chang Hojin , Lee Yong Sang , Song Yong , Chang Hang-Seok 
Published: July 2023

Abstract
Recent advances in thyroid surgery techniqueshave increased the number of patients undergoing transoral thyroidectomy, and many patients are concerned about the post-thyroidectomy cosmetic effects. This study was conducted from August 2021 to January 2022 at Gangnam Severance Hospital (Seoul, South Korea), a tertiary hospital; a total of 91 patients underwent transoral endoscopic thyroidectomy (TOET) or open thyroidectomy performed by a single surgeon. Before and after surgery, the Hospital Anxiety and Depression Scale (HADS), Pain Catastrophizing Scale, 15-Item Quality of Recovery, and Post-traumatic Stress Disorder Checklist surveys were administered. The survey results of the patients who underwent TOET and those who underwent open thyroidectomy were compared to determine the differences. Patients with insufficient survey data were excluded. Only the HADS-Depression survey scores differed significantlybetween the TOET and open thyroidectomy groups and were 4.22±0.781 and 5.52±0.84, respectively (p=.039). Multivariable analysis, adjusted for age and weight differences between the conventional and TOET groups, revealed no differences in any of the survey scores, including the HADS-Depression scores. No differences were observed in the survey scores between the TOET and open thyroidectomy groups. Thus, subjective postoperative stress about pain and the degree of recovery after surgery were similar between the two groups.