bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of modern e-health services including telemedicine and telepharmacy for remote patient care in Saudi Arabia
Authors: Alhomoud Farah K. 
Published: January 2025

Abstract:

BACKGROUND:
Numerous preventive measures and regulations including electronic health (e-health) services were implemented during the coronavirus pandemic. Despite their importance, very little is known about their use. Therefore, the aim of this study was to determine the use of e-health application by healthcare providers (HCPs), and assess their awareness, perceptions, and practices of such services.

MATERIALS AND METHODS:
A cross-sectional study was conducted during July to September 2024 using online self-administered questionnaires. Participants were selected using convenient sampling technique supplemented by snowball sampling. The calculated sample size was 218 participants. Data was collected through an online pretested English-language questionnaire. SPSS version 26 was used to analyze data; Chi-square test was used to examine the associations between HCPs’ responses regarding perceived benefits, risks, and needs related to e-health tools.

RESULTS:
Of the 471 survey participants who started filling out the survey, 64% (n=300) reported using e-health services since coronavirus disease and were included in the final analysis. Female HCPs used e-health applications twice as often as males, and a decline in e-health use was seen with increasing age of participants. Most common purpose for using e-health services were treatment (61%), consultations (60%), and follow up with patient (54%). The most used e-health tools were telephones or cell phones (69.0%) and WhatsApp applications (64.0%) followed by Zoom application (50.0%) and Sehhaty application. Technical problems such as poor internet connection and automatic updates of applications were reported by more than half of the users (52%). Participants reported perceived risks regarding privacy and data protection, and clinical risks associated with using e-health tools.

CONCLUSION:
HCPs’ positive experiences with e-health services in Saudi Arabia, valued for their cost-effectiveness and efficiency. However, patient misinterpretation, privacy risks, and clinical errors persist. Growing demand underscores the need for more explicit e-health regulations and broader professional involvement to enhance e-health service.
Adverse Drug Reactions and Associated Socio-demographic Factors amongst Drug-resistant Tuberculosis Patients: A Retrospective Review
Authors: Tiwari Rajesh , Bharti Aditi , Tomar Akanksha 
Published: January 2025

Abstract

Background:
Drug-resistant tuberculosis (DR-TB) needed prolonged treatment using the majority of second-line drugs (SLDs). Most of SLDs are reported to be associated with a higher rate of adverse drug reactions (ADRs), which may be a deterrent to treatment compliance. Hence, timely and intensive monitoring and management of ADR are essential components of the programmatic management of DR-TB (PMDT) to enhance treatment outcomes.

Aim:
This study aimed to evaluate the occurrence, management and risk factors for ADRs in DR-TB patients, and its association with treatment outcomes at a designated DR-TB Centre.

Patients and Method:
A record-based review was conducted at the district DR-TB Centre, Jabalpur, Madhya Pradesh. Study participants included patients enrolled under PMDT guidelines from January 2018 to December 2019. Conventional multidrug-resistant TB patients and transferred-out cases were excluded. Data collection and review were done through the NIKSHAY portal, PMDT treatment cards, ward DR-TB registers and case sheets traced by NIKSHAY ID. The severity of ADR was assessed using the Modified Scale of Hartwig and Siegel into mild, moderate and severe. Data were analysed using IBM SPSS software version 20. Chi-square test and t-test were applied, with a 95% confidence interval considering P ≤ 0.05 to be significant.

Results:
Out of 221 DR-TB patients, 42 patients reported at least one ADR (19%). Amongst these, a total of 78 episodes were reported during their course of treatment. Most frequent ADRs were related to the gastrointestinal system (47.5%), followed by weakness (17.9%) and jaundice or body aches (7.7% each). Most (73.1%) of the ADRs were mild to moderate while only 26.9% were severe on Hartwig and Siegel scale. Successful treatment outcome (cured and treatment completed) is reported to be 61.1% overall while only 35.7% amongst those reporting ADR. Moreover, treatment outcomes and low socio-economic status were statistically significant with ADRs.

Conclusion:
In this study, ADR is found to be reported by one-fifth of the patients. All were successfully managed without requiring any change of regime. However, reporting an ADR is significantly associated with unsuccessful treatment outcomes of DR-TB.
TINJAUAN HUKUM TERHADAP WANPRESTASI OLEH KREDITUR YANG MEMBERLAKUKAN PENGAKHIRAN KONTRAK SEPIHAK KEPADA DEBITUR DALAM PERJANJIAN SEWA PAKAI PROPERTI
Authors: Batubara Rosiana Agnes Rizky , Habeahan Besty 
Published: January 2025

Sasaran penelitian ini adalah untuk menggali pemahaman yang lebih mendalam seta menguraikan secara benar tentang perilaku wanrprestasi oleh si kreditur terhadap debitur dimana ia melakukan pengakhiran kontrak secara sepihak dalam perjanjian sewa pakai yang sudah pasti sangat jelas bahwa perilaku tersebut melanggar apa yang sudah diatur didalam perundang-undangan dan mencabut hak yang seharusnya didapatkan oleh si debitur. Metode yang digunakan didalam penelitian ini yakni pendekatan hukum doktrinal atau normatif dimana itu pada dasarnya mengkaji mengenai aspek internal dari hukum positif. Dimana dasar yang diambil dalam penelitian ini berfokus pada peraturan perundang-undangan khususnya Kitab Undang-Undang Hukum Perdata atau Burgelijk wetboek, pendapat ahli dan peraturan sejenisnya. Penelitian ini juga lebih terfokus pada lingkup konsepsi hukum, asas serta kaidah didalam hukum. Didalam perjanjian atau hukum perjanjian, tindakan pengakhiran kontrak secara sepihak itu sebenarnya diperbolehkan namun harus mengikuti ketentuan yang terdapat didalam pasal 1266 KUHPerdata dan saat pengakhiran kontrak tersebut haruslah benar berdasarkan kesepakatan dari kedua belah pihak dan meminta persetujuan kepada Pengadilan Negeri didaerah tempat mereka tinggal. Jika salah satu piihak melanggar pasal tersebut, terkhusus seperti kreditur yang ada didalam penelitian, sehingga pihak yang mendapatkan kerugian dapat memintakan ganti rugi kepadanya dan dapat menjalani proses penyelesaian sengketa dengan 2 (dua) cara yaitu pengadilan ataupun menggunakan cara penyelesaian sengketa diluar pengadilan (metode ADR).
Computational drug repurposing for tuberculosis by inhibiting Ag85 complex proteins
Authors: Iskandar Israini W. , Nurhasanah Astutiati , Hatta Mohammad , Hamid Firdaus , Handayani Irda , Chaera Ummi , Yusriyyah Andi A. , Jamaluddin Balqis D. , Zaenab St , Hidayah Najdah , Karimah Nihayatul , Permana Andi D. , Massi Muhammad N. 
Published: January 2025

Tuberculosis (TB) remains a significant and deadly infection among pulmonary diseases caused by Mycobacterium tuberculosis, a highly adaptive bacterium. The ability of M. tuberculosis to evade certain drugs has been linked to its unique structure, particularly in the cell envelope, where the Ag85 complex proteins play an essential role in this part. The aim of this study was to utilize a drug repurposing strategy targeting the Ag85 complex proteins. This study utilized a computational approach with 120 selected drugs experimentally identified to inhibit Tuberculosis. A virtual screening molecular docking with Autodock Vina was used to filter the compounds and identify the strong binders to the Ag85 Complex. Molecular dynamics simulations employed the Gromacs Packages to evaluate the stability of each complex, including root mean square deviation (RMSD), root mean square fluctuation (RMSF), and radius of gyration (RoG). Additionally, absorption, distribution, metabolism, excretion, and toxicity (ADMET) assessments were conducted to gather more information about the drug-likeness of each hit compound. Three compounds, selamectin, imatinib, and eltrombopag were selected as potential drugs repurposed to inhibit the activity of the Ag85 complex enzyme, with binding affinities ranging between -10.560 kcal/mol and -11.422 kcal/mol. The MD simulation within 100 ns (3 replicas) showed that the average RMSD of each Ag85A complex was 0.15 nm–0.16 nm, RMSF was 0.09 nm–0.10 nm, and RoG was 1.80 nm–1.81 nm. For Ag85B, the average RMSD was 1.79 nm–1.80 nm, RMSF was 0.08 nm–0.09 nm, and RoG was 1.79 nm – 1.80 nm. Then, for Ag85C, the mean RMSD was 0.16 nm–0.18 nm, RMSF was 0.09, and RoG was 1.77 nm. The study highlights that these promising results demonstrate the potential of some repurposed drugs in combating the Ag85 complex.
Investigation of Inner and Outer Flow Field Characteristics of Pyramidal Roof Rectangular Base Building Due to Synoptic Wind Flow through it by Changing the Wall Porosity of the Building.
Authors: Franky Kumar Kalia  
Published: January 2025

A key component of building design involves understanding the flow field that develops near a building due to synoptic wind flow across it. The wind environment around buildings is important for their structural strength, but it also has an impact on ventilation effectiveness, pedestrian comfort, and the spread of pollutants. Modern structures now have a variety of apertures, including windows, doors, and ventilators, leading to the rise of the green building idea and environmentally friendly living. The flow field becomes more complex as a result of these apertures, which alter the flow properties inside and outside the building. The goal of the current study is to better understand the flow fields surrounding the structures with openings, both internally and externally. This study aims to examine the wind flow over structures with Pyramidal roof rectangular base building that have openings exposed to synoptic winds. Using the Computational Fluid Dynamics (CFD) approach, internal flow within the buildings is also examined for optimal ventilation. Numerical simulations are conducted using ANSYS-FLUENT, a commercially available CFD program. The steady Reynolds Averaged Navier Stokes (RANS) equations are solved by numerical simulations. This study examines the effects of various wall porosities on the building façade as well as the relative vertical placements of the openings. The flow field both within and outside of buildings is significantly impacted by wall porosities and the relative vertical positions of openings on building facades. The internal pressure distribution and air flow rate are greatly influenced by the wall porosity. The study provides information about the flow environment within and outside of a low-rise building with Pyramidal roof rectangular base building with openings, which is useful for estimating wind loads for the building's structural design and for creating a natural ventilation system.
Ștefan Vianu, Sens interzis. Adevăr, devenire, locuire, Iași, Editura Polirom, 2024.
Authors: Stanciulescu Catalin 
Published: January 2025

Ștefan Vianu's work, Forbidden Meaning. Truth, Becoming, Habitation, contains ten essays on the phenomenology of life, understood as a description of the conditions in which any attempt to transform the inner life into the essence of the interior life can become possible starting from poetic language (in a somewhat generic sense, encompassing mythical thought, religion, art, imagination, literary works, cultural values), if not at least different from scientific and everyday language (essential difference, explored and exploited in multiple ways, in the web of ideas of the book).
Prevalence of fear of childbirth, its risk factors and birth outcomes in Australian multiparous women
Authors: Li Rui-Xin , Asgharvahedi Farnoosh , Khajehei Marjan 
Published: January 2025

BACKGROUND
Fear of childbirth (FoC) is a widespread issue that impacts the health and well-being of mothers and newborns. However, there is inconsistency regarding the prevalence of FoC in the and there is limited research on the prevalence of FoC among Australian pregnant women.
AIM
To investigate the prevalence of FoC, its risk factors and birth outcomes in Australian multiparous women.
METHODS
In this prospective cohort quantitative study, 212 multiparous women were recruited from antenatal clinics at Westmead Hospital in western Sydney from 2019 to 2022. Pregnant women who attended antenatal visits and met the inclusion criteria signed the consent forms and completed several online questionnaires at baseline. After they gave birth, their birth outcomes were collected from the hospital’s medical record database. The data were analyzed using SPSS software and descriptive statistics, χ 2 test, independent samples t -test, and multivariable logistic regression analysis.
RESULTS
Out of 212 participants, 24% experienced a high level of FoC and 7% experienced severe FoC. The χ 2 test results revealed that a family income of ≤ $100000, no alcohol intake during pregnancy, pre-existing health problems, previous caesarean section (emergency or planned), and previous neutral/traumatic childbirth experiences were significantly associated with higher levels of FoC (P < 0.05). Other risk factors included being moderately to very worried and fearful about the upcoming birth, having severe to extremely severe anxiety throughout pregnancy, and expressing low relationship satisfaction. According to multivariable logistic regression, the odds of a high level of FoC were higher in women with anxiety, a history of traumatic childbirth experience, a history of sexual assault during childhood, pre-existing health problems, and lower relationship satisfaction (P < 0.05).
CONCLUSION
High-severe levels of FoC are experienced by pregnant multiparous women and are affected by several demographic factors. However, due to the small sample size in the present study, further studies with larger sample sizes are required to draw a firm conclusion on the prevalence of severe FoC among multiparous women and its associated risk factors and birth outcomes.
ВЕБЗАСТОСУНОК ПРИЙНЯТТЯ РІШЕНЬ ЩОДО ВИБОРУ ОПТИМАЛЬНОГО ПОСТАЧАЛЬНИКА
Authors: ТКАЧЕНКО Олександр Андрійович , ТАРАСОВ Дмитро Сергійович 
Published: January 2025

В наш час підприємницька діяльність є рушієм розвитку, зростання, інновацій та соціальних змін у суспільстві, державі. Розгляд поданих щодо замовлень (на товари, продукцію, роботи чи послуги) пропозицій часто проводяться без використання відповідних іструментів автоматизації, що обумовлює його трудомісткість та тривалість, особливо якщо пропозицій та критеріїв відбору багато. Тому не викликає сумніві актуальність проблеми створення відповідного вебзастосунку, який дозволить автоматизувати даний процес на основі визначених замовником критеріїв.
Метою роботи є аналіз та дослідження проблем і методів вибору оптимального постачальника товарів (продукції підприємств, послуг) та розробки відповідного програмного продукту – вебзастосунку прийняття рішень щодо автоматизованого вибору оптимального постачальника для виконання замовлення (закупівлі товару, продукцій, роботи чи послуги).
Вибір постачальника є одним з найважливіших етапів проведення закупівель товарів, робіт та послуг. У роботі було проаналізовано і досліджено метод багатокритеріальної оптимізації з використанням згортки Вороніна, який може бути використано для вирішення задач вибору постачальника при здійсненні закупівель.
Використання авторського вебзастосунку прийняття рішень щодо вибору оптимального постачальника для виконання замовлення по закупівлі товарів дозволяє, зокрема: надавати користувачеві можливість вибору оптимального постачальника; оптимізувати процес виконання замовлення за рахунок автоматизованого вибору постачальника серед тих, які подали пропозицію на замовлення (при створенні замовлення кожен замовник визначає критерії оптимальності, які для нього є найбільш вагомими); користувачеві не потрібно знатись на математичних аспектах багатофакторного аналізу та оптимізації через те, що це виконує сам вебзастосунок; згенерувати кілька варіантів рішень вибору постачальника, що відповідають потребам замовника згідно з критеріями оцінки постачальників. Використання розробленого вебзастосунку автоматизує процес вибору оптимального постачальника при здійсненні закупівель, що дозволить підвищити конкурентоспроможність підприємств (підприємців), зменшити витрати на закупівлі.
Shaping the itinerary: Perceived quality of recommendation systems on travel intentions. A case study in Vietnam
Authors: Dat Nguyen Van , Tho Nguyen Van 
Published: January 2025

This study aims to explore how recommendation systems (RS) influence the decision-making process of tourists. By examining the quality of RS, their impact on travel intentions, and the mediating role of satisfaction, the study seeks to model the decision-making process more effectively. Data were collected through a survey of 523 consumers in Vietnam who had previously used RS, employing a convenience sampling method. The survey questionnaire was distributed via email in the form of Google Forms. The study established a conceptual framework and tested the hypotheses using structural equation modeling (SEM). SPSS 26 was employed to assess the reliability of measurement scales, while AMOS 28 was used to evaluate the measurement and structural models. The findings indicate that consumers' positive perceptions of information quality, system quality, trust, and the usefulness of RS significantly enhance satisfaction and travel intentions. Notably, personalization does not directly influence perceived RS quality but exerts an indirect effect through the usefulness of RS. Satisfaction serves as a critical mediator in the relationship between perceived RS quality and travel intentions, emerging as the most influential factor within the model. This study underscores the effectiveness of decision-making driven by perceived RS quality in the tourism context. These findings provide valuable insights for policymakers and system developers to improve RS quality, thereby attracting tourists, enhancing competitive advantages in the tourism industry.
Danse Hip Hop et Mieux-être de jeunes en contextes éducatifs de vulnérabilité
Authors: THOREL-HALLEZ Sabine 
Published: January 2025

Cet article vise à éclairer les processus qui agissent positivement sur le rapport à soi et aux autres de jeunes de 13 à 18 ans à travers la danse hip hop. Deux dispositifs sont investigués : celui d'un Établissement Pénitentiaire pour Mineurs et celui d'un collège dont les supports artistiques sont des éléments de prévention de conduites à risque. A partir d’un cadre théorique composite sont examinés les effets des usages du hip hop sur ces adolescents en termes de relations sociales et d’accomplissement personnel. L’analyse des pratiques puis des entretiens (chorégraphe, chargée de projet, éducateur) mettent en relief des relations interpersonnelles basées sur la confiance, l'accompagnement, l'authenticité de l’adulte. Les dispositifs construits sur l’écoute et la valorisation sont un moyen d’accomplissement de ces jeunes. Relations sociales, plaisir et liberté ressentis lors de ces ateliers et transformations corporelles attestent d’un bien-être.
Entrer en formation au métier d’enseignant à l’Ecole Normale Supérieure : contexte et logiques de décision au Burkina Faso
Authors: OUEDRAOGO Mangawindin Guy Romuald 
Published: January 2025

Le Burkina Faso connaît une crise de l’emploi se manifestant par une insuffisance de l’offre d’emploi par l’Etat et le secteur privé aux diplômés. Le recensement général de la population de 2019 révèle un taux d’inactivité de 53,8% dans la population de 15 ans et plus (INSD, 2022). Dans un tel contexte, la chance d’obtenir un emploi est très infime au regard de la grande masse de demandeurs. Il apparaît alors important et légitime d’interroger les raisons qui poussent les étudiants à candidater au concours d’entrée à l’Ecole Normale Supérieure pour la formation initiale des enseignants du post-primaire et du secondaire. Cette recherche avait pour objectif principal d’identifier chez les stagiaires de l’Ecole Normale Supérieure, dans une approche sociologique du travail, les déterminants motivationnels de leur entrée en formation initiale. L’approche d’analyse s’est inscrite dans la théorie de la motivation à la protection de Rogers (1975 ; 1983). La méthode de recherche a été qualitative, consistant en des entretiens avec les stagiaires en formation initiale à l’Ecole Normale Supérieure. Leurs déclarations ont été analysées et interprétées sous le prisme de la théorie de Rogers. Au final, les résultats de l’enquête révèlent bien que la motivation du stagiaire à entrer à l’Ecole Normale supérieure provient moins d’une quête de compétences professionnelles pour son futur métier d’enseignant que du besoin de sécurisation socioprofessionnelle en intégrant la Fonction Publique. Cette réalité commande de mettre en place un dispositif d’accompagnement des stagiaires pour une compréhension de l’importance de la formation initiale dès leur entrée à l’Ecole Normale Supérieure.
Sexe et perception de la relation enseignante des élèves de la 6e année de l’académie d’enseignement de Bamako rive droite
Authors: COULIBALY Soumaïla , SIDIBÉ Moctar , DAKOUO Jacques Mawé 
Published: January 2025

La perception de la relation enseignant-élève est une des variables explicatives de la performance scolaire. Nous avons jugé nécessaire de chercher à comprendre si toutefois il y a une différence entre les filles et les garçons pour ce qui concerne leur perception de la relation avec l’enseignant. Pour ce faire, nous avons mené une enquête auprès des élèves de la 6e année des groupes scolaires publics de l’académie d’enseignement de Bamako rive droite. La technique d’échantillonnage par quotas nous a permis de constituer un échantillon de 370 élèves dont 188 garçons et 182 filles. Le questionnaire a servi à recueillir les données afin de vérifier l’hypothèse suivante : les filles, contrairement aux garçons, ont une perception positive de leur relation avec l’enseignant. Le test de khi deux a permis de tester l’hypothèse à l’étude, précisément si la différence entre la perception de la relation de filles et celle de garçons avec l’enseignant est significative. Les résultats ont permis d’infirmer notre hypothèse. La différence entre les filles et les garçons pour ce qui concerne la perception de la relation avec l’enseignant n’est pas significative. Ainsi, nous avons préconisé que les enseignants doivent ajuster leurs pratiques et attitudes à l’égard des filles et des garçons afin que ceux-ci aient une bonne perception de leur relation dans le but d’optimiser la performance de ces derniers à l’école.