bluuebunny/crossref_metadata_2025_split huggingface dataset:
Back to the basics of polar expeditions: personality hardiness, fear, and nutrition in polar environments
Authors: Johnsen Bjørn Helge , Gjeldnes Rune 
Published: February 2023

AbstractThe present paper aims at presenting an overview of findings relating personality hardiness to adaptation to polar environments. Several studies from the Operational Psychology Research group at the University of Bergen have depicted individual characteristics of high hardy subjects involved in stressful activities in polar environments. These high hardy subjects have superior coping skills, are less influenced by environmental stress, show increased motivation during endurance activities, and have a more adaptive biological stress response. It could be assumed that explorers undertaking solo expeditions in polar environments would represent extremely hardy people. Thus, in addition to previously reported studies on hardiness in polar environment, the results from two previously published papers are presented and re-interpreted. The studies provided a rare opportunity to separate the effects of extreme physiological and emotional strain (mainly fear) and present the trajectory of relevant biomarkers of fear, stress, appetite, and nutritional status during a 90-day expedition across Antarctica. The studies expanded on previous knowledge by showing extreme variations in biomarkers during the expedition and suggested that extreme fear has the highest impact on indicators of stress, stress regulation, appetite, and nutritional status. This, together with the recovery effects found on nutrition status after a daily energy uptake of 5–6000 kcal, expands on previous knowledge about adaptation in polar environments.
One stage correction via the Hi-PoAD technique for the management of severe, stiff, adolescent idiopathic scoliosis curves > 90°
Authors: Faldini Cesare , Viroli Giovanni , Barile Francesca , Manzetti Marco , Ialuna Marco , Traversari Matteo , Vita Fabio , Ruffilli Alberto 
Published: February 2023

Abstract
Study design
Retrospective cohort study.

Purpose
to assess the efficacy and safety of Hi-PoAD technique in patients with a major thoracic curve > 90°, < 25% of flexibility and deformity spread over more than five vertebral levels.

Methods
retrospective review of AIS patients with a major thoracic curve (Lenke 1–2–3) > 90°, with < 25% of flexibility and deformity spread over more than five vertebral levels. All were treated via the Hi-PoAD technique. Radiographic and clinical score data were collected pre-operatively, operatively, at 1 year, 2 years and at last follow-up (2 years minimum).

Results
19 patients were enrolled. A 65.0% correction rate of the main curve was achieved, from 101.9° to 35.7° (p < 0.001). The AVR reduced from 3.3 to 1.3. The C7PL/CSVL reduced from 1.5 to 0.9 cm (p = 0.013). Trunk Height increased from 31.1 to 37.0 cm (p < 0.001). At the final follow-up no significant changes, except from an improvement in C7PL/CSVL (from 0.9 cm to 0.6 cm; p = 0.017). SRS-22 increased in all patients, from 2.1 to 3.9 at 1 year of follow-up (p < 0.001). 3 patients had a transient drop of MEP and SEP during maneuver and were managed with temporary rods and a second surgery after 5 days. 2 of these 3 cases (66.7%) had a Total-Deformity Angular Ratio (T-DAR) > 25; conversely, among patients who had a one-stage procedure, only 1 (6.2%) had a T-DAR > 25 (p = 0.008).

Conclusions
The Hi-PoAD technique proved to be a valid alternative for the treatment of severe, rigid AIS involving more than 5 vertebral bodies.

Study design
Retrospective comparative cohort study.

Level of evidence
III.
AtBBX29 integrates photomorphogenesis and defense responses in Arabidopsis
Authors: Medina-Fraga Ana L. , Chinen Lucas A. , Demkura Patricia V. , Lichy Micaela Z. , Gershenzon Jonathan , Ballaré Carlos L. , Crocco Carlos D. 
Published: February 2023

AbstractLight is an environmental signal that modulates plant defenses against attackers. Recent research has focused on the effects of light on defense hormone signaling; however, the connections between light signaling pathways and the biosynthesis of specialized metabolites involved in plant defense have been relatively unexplored. Here, we show that Arabidopsis BBX29, a protein that belongs to the B-Box transcription factor (TF) family, integrates photomorphogenic signaling with defense responses by promoting flavonoid, sinapate and glucosinolate accumulation in Arabidopsis leaves. AtBBX29 transcript levels were up regulated by light, through photoreceptor signaling pathways. Genetic evidence indicated that AtBBX29 up-regulates MYB12 gene expression, a TF known to induce genes related to flavonoid biosynthesis in a light-dependent manner, and MYB34 and MYB51, which encode TFs involved in the regulation of glucosinolate biosynthesis. Thus, bbx29 knockout mutants displayed low expression levels of key genes of the flavonoid biosynthetic pathway, and the opposite was true in BBX29 overexpression lines. In agreement with the transcriptomic data, bbx29 mutant plants accumulated lower levels of kaempferol glucosides, sinapoyl malate, indol-3-ylmethyl glucosinolate (I3M), 4-methylsulfinylbutyl glucosinolate (4MSOB) and 3-methylthiopropyl glucosinolate (3MSP) in rosette leaves compared to the wild-type, and showed increased susceptibility to the necrotrophic fungus Botrytis cinerea and to the herbivore Spodoptera frugiperda. In contrast, BBX29 overexpressing plants displayed increased resistance to both attackers. In addition, we found that AtBBX29 plays an important role in mediating the effects of ultraviolet-B (UV-B) radiation on plant defense against B. cinerea. Taken together, these results suggest that AtBBX29 orchestrates the accumulation of specific light-induced metabolites and regulates Arabidopsis resistance against pathogens and herbivores.
Graphical Abstract
Longitudinal stability of
gyroplanes
Authors: Houston S. S. 
Published: February 2023

AbstractThe class of aircraft known as gyroplanes (or
autogyros) helped to pave the way for the
development of the helicopter. However, they have
found no application in contemporary commercial or
military aviation. It is in recreational or sport
flying that the gyroplane has proved popular. Most
if not all designs are however homebuilts, and as a
consequence little analysis of any significance has
been conducted on the flight mechanics of these
aircraft. This Paper presents an analysis of the
longitudinal stability of gyroplanes. Simple
consideration of the basic forces and moments that
might influence stability, in the context of
elementary rotor behaviour, is used to assess the
fundamental nature of gyroplane longitudinal
stability. This is quantified by the application of
a sophisticated generic rotorcraft mathematical
model to the gyroplane problem. It is concluded that
the basic configuration can be longitudinally stable
with appropriate design, and that the rotorspeed
degree of freedom must also be included when
modelling the aircraft.
Automatic grid generation for complex
geometries
Authors: Smith R. J. , Leschziner M. A. 
Published: February 2023

AbstractA novel automatic grid generation method for complex
CFD applications has been developed, driven by the
need of the industrial CFD practitioner to reduce
the turnaround time from an initial CAD geometry to
obtaining a flow simulation. The method uses a
subdivision strategy, allowing hanging nodes in a
Cartesian unstructured mesh environment and is
combined with a non-overlapping, semi-structured
surface grid. Unusually, the surface grid is the end
rather than the starting point of the present
approach. This reversal of gridding strategy allows
usability to be enhanced, in that the grid
generation is reduced to one automatic step. The
capabilities of the method are demonstrated by
reference to selected inviscid and viscous flow
solutions using the Fluent code Rampant v4.0 as a
flow solver.
Rutile Ages and Thermometry Along a Grenville Anorthosite Pathway
Authors: Liebmann Janne , Barham Milo , Kirkland Christopher L. 
Published: February 2023

AbstractThe Grenville Orogen, in North America, contains a belt of Proterozoic anorthosite massifs with an episodic emplacement history. These distinctive magmas reflect extensive fractional crystallization of plagioclase from a mafic magma and contain layers dominated by Ti‐bearing minerals including ilmenite and rutile. U‐Pb geochronology and Zr‐in‐rutile analyses from the Lac Malbaie complex in the Saint Urbain area of Quebec help to constrain the tectonothermal history of repeated anorthosite emplacement into the crust. Geologically significant dates were obtained from low‐U (<2 ppm) rutile in anorthosite drill cores and a boulder. Rutile ages of c. 1158, 1069–1056, and 936–910 Ma are interpreted to reflect variable modification of cooling ages during later intrusion and fluid mobilization events. Zr‐in‐rutile temperatures track higher apparent temperatures of >800°C in earlier events. Apparently younger rutile grains, and those influenced by fast pathway diffusion, record lower apparent temperatures. The Grenville Orogen comprises major trans‐lithospheric structures that facilitate the repeated bottom‐up transit of mantle‐derived magmas. At depth this led to the emplacement of anorthositic magmas whose thermal pathway is tracked by rutile passing through their Pb blocking temperature during crustal unroofing. This same broad crustal architecture, in the comparatively shallow crust, provided a favorable pathway for top‐down hydrothermal fluids to interact with younger rutile as successive anorthosites were emplaced. Rutile demonstrates that the current crustal section represents the juxtaposition of minerals preserving information from different thermal regimes, retaining vestiges of a protracted history due to incomplete re‐equilibration with subsequent chemical or thermal conditions.
Origin of 182W Anomalies in Ocean Island Basalts
Authors: Archer Gregory J. , Budde Gerrit , Worsham Emily A. , Stracke Andreas , Jackson Matthew G. , Kleine Thorsten 
Published: February 2023

AbstractOcean island basalts (OIB) show variable 182W deficits that have been attributed to either early differentiation of the mantle or core‐mantle interaction. However, 182W variations may also reflect nucleosynthetic isotope heterogeneity inherited from Earth's building material, which would be evident from correlated 182W and 183W anomalies. Some datasets for OIB indeed show hints for such correlated variations, meaning that a nucleosynthetic origin of W isotope anomalies in OIB cannot be excluded. We report high‐precision W isotope data for OIB from Samoa and Hawaii, which confirm previously reported 182W deficits for these samples, but also demonstrate that none of these samples have resolvable 183W anomalies. These data therefore rule out a nucleosynthetic origin of the 182W deficits in OIB, which most likely reflect the entrainment of either core material or an overabundance of late‐accreted materials within OIB mantle sources. If these processes occurred over Earth's history, they may have also been responsible for shifting the 182W composition of the bulk mantle to its modern‐day value. We also report Mo isotope data for some Hawaiian OIB, which reveal no resolved nucleosynthetic Mo isotopic anomalies. This is consistent with inheritance of 182W deficits in OIB from the addition of either core or late‐accreted material, but only if these materials have a non‐carbonaceous (NC) meteorite‐like heritage. As such, these data rule out significant contributions of carbonaceous chondrite (CC)‐like materials to either Earth's core or late accretion.
Modulation of Cyclones With Tropical and Extratropical Origins by Mesoscale SSTs in the Kuroshio Extension Region
Authors: Zhang Xingzhi , Ma Xiaohui , Ma WeiWei , Wu Lixin , Liu Qinyu , Zhang Li , Wang Baiping 
Published: February 2023

AbstractTwo typical classes of cyclones originating from the tropics (ToCs) and extratropics (EoCs) with distinct preconditions, and passing the Kuroshio Extension (KE) region in cold season in the North Pacific are detected and tracked based on high‐resolution atmospheric simulations with and without mesoscale sea surface temperature (SST) forcing. A comparison between ToC‐to‐mesoscale SST and EoC‐to‐mesoscale SST responses indicates that the different cyclone development and the environmental water vapor restoration in the KE are primarily attributed to different ToC and EOC's preconditions. The higher initial intensity of ToCs leads to stronger atmospheric response to mesoscale SSTs and extended cyclone growth whilst the colder and drier precondition of EoCs induces stronger water vapor restoration in the KE after EoCs passing‐by. It is further demonstrated that the water vapor restoration is dominated by moisture convergence. The study provides new insights into the physical understanding of mesoscale SSTs' influence on cyclogenesis in the midlatitudes.
Reconciling Observations of Solar Irradiance Variability With Cloud Size Distributions
Authors: Mol Wouter B. , van Stratum Bart J. H. , Knap Wouter H. , van Heerwaarden Chiel C. 
Published: February 2023

AbstractClouds cast shadows on the surface and locally enhance solar irradiance by absorbing and scattering sunlight, resulting in fast and large solar irradiance fluctuations on the surface. Typical spatiotemporal scales and driving mechanisms of this intra‐day irradiance variability are not well known, hence even 1 day ahead forecasts of variability are inaccurate. Here, we use long‐term, high‐frequency solar irradiance observations combined with satellite imagery, numerical simulations, and conceptual modeling to show how irradiance variability is linked to the cloud size distribution. Cloud shadow sizes are distributed according to a power law over multiple orders of magnitude, deviating only from the cloud size distribution due to cloud edge transparency at scales below ≈750 m. Locally cloud‐enhanced irradiance occurs as frequently as shadows, and is similarly driven mostly by boundary layer clouds, but distributed over a smaller range of scales. We reconcile studies of solar irradiance variability with those on clouds, which brings fundamental understanding to what drives irradiance variability. Our findings have implications not only for weather and climate modeling, but also for solar energy and photosynthesis by vegetation, where detailed knowledge of surface solar irradiance is essential.
Seasonality of brain function: role in psychiatric disorders
Authors: Zhang Rui , Volkow Nora D. 
Published: February 2023

AbstractSeasonality patterns are reported in various psychiatric disorders. The current paper summarizes findings on brain adaptations associated with seasonal changes, factors that contribute to individual differences and their implications for psychiatric disorders. Changes in circadian rhythms are likely to prominently mediate these seasonal effects since light strongly entrains the internal clock modifying brain function. Inability of circadian rhythms to accommodate to seasonal changes might increase the risk for mood and behavior problems as well as worse clinical outcomes in psychiatric disorders. Understanding the mechanisms that account for inter-individual variations in seasonality is relevant to the development of individualized prevention and treatment for psychiatric disorders. Despite promising findings, seasonal effects are still understudied and only controlled as a covariate in most brain research. Rigorous neuroimaging studies with thoughtful experimental designs, powered sample sizes and high temporal resolution alongside deep characterization of the environment are needed to better understand the seasonal adaptions of the human brain as a function of age, sex, and geographic latitude and to investigate the mechanisms underlying the alterations in seasonal adaptation in psychiatric disorders.
Rational thinking as a mediator of the relationship between mindfulness and dental anxiety
Authors: Yao Jiaxuan , Carciofo Richard , Pan Li 
Published: February 2023

AbstractDental anxiety causes people to postpone or refuse to go to the dentist, which further negatively impacts their quality of life and public health. Previous research has shown that mindfulness is inversely related to anxiety. However, little is known about the relationship between mindfulness and dental anxiety. The current research aimed to explore the relationship between mindfulness and dental anxiety and investigate the mediating role of rational thinking. Two studies were conducted. In study one, 206 Chinese participants completed questionnaires measuring trait mindfulness and dental anxiety (state, responding to a dental treatment scenario). In study two, 394 participants completed questionnaires measuring trait mindfulness, dental anxiety (trait), and rational thinking. The results for both studies showed that mindfulness is negatively correlated with dental anxiety. In study 1, each facet of mindfulness except Non-judging was negatively correlated with dental anxiety with Acting with Awareness having the strongest correlation, while in study 2, only Acting with Awareness was significantly negatively correlated with dental anxiety. Furthermore, rational thinking mediated the effect of mindfulness on dental anxiety. In conclusion, mindfulness is negatively related to both state and trait dental anxiety, and rational thinking mediates the relationship between mindfulness and dental anxiety. Implications of these findings are discussed.
Comparison of RT-qPCR and RT-ddPCR with Rift valley fever virus (RVFV) RNA
Authors: Park Changwoo , Park Dongju , Hassan Zohaib Ul , Choi Sang Ho , Kim Seil 
Published: February 2023

AbstractRift valley fever (RVF) is an important zoonotic disease caused by the Rift valley fever virus (RVFV) which can affect ruminants and humans. In this study, a comparison was done of the reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and reverse transcription-droplet digital PCR (RT-ddPCR) assays with synthesized RVFV RNA, cultured viral RNA, and mock clinical RVFV RNA samples. The genomic segments (L, M, and S) of three RVFV strains (BIME01, Kenya56, and ZH548) were synthesized and used as templates for in vitro transcription (IVT). Both the RT-qPCR and RT-ddPCR assays for RVFV did not react with any of the negative reference viral genomes. Thus, both the RT-qPCR and RT-ddPCR assays are specific to RVFV. The comparison of both the RT-qPCR and RT-ddPCR assays with serially diluted templates showed that the LoD of both assays are similar, and a concordant of the results was observed. The LoD of both assays reached the practical measurable minimum concentration. Taken altogether, the sensitivity of the RT-qPCR and RT-ddPCR assays is similar, and the material measured by RT-ddPCR can be used as a reference material for RT-qPCR.
Effect of total knee replacement on skeletal muscle mass measurements using dual energy X-ray absorptiometry
Authors: Jang Jae Young , Kim Miji , Lee Daehyun , Won Chang Won 
Published: February 2023

AbstractSarcopenia is becoming prevalent in an increasing number of older adults undergoing total knee replacement (TKR) surgery. Metal implants may overestimate lean mass (LM) measured using dual-energy X-ray absorptiometry (DXA). This study aimed to examine the effects of TKR on LM measurements according to automatic metal detection (AMD) processing. The participants from Korean Frailty and Aging Cohort Study, who had underwent TKR were enrolled. A total of 24 older adults (mean age 76.4 ± 4.0 years, 92% female) were included in the analysis. The SMI with AMD processing was 6.1 ± 0.6 kg/m2, which was lower than that without AMD processing of 6.5 ± 0.6 kg/m2 (p < 0.001). The LM of the right leg with AMD processing was lower than that without AMD in 20 participants who had underwent TKR surgery on the right (5.5 ± 0.2 kg vs. 6.0 ± 0.2 kg, p < 0.001), and that of the left leg was also lower in with AMD processing than in without AMD processing in 18 participants who had underwent TKR surgery on the left (5.7 ± 0.2 kg vs. 5.2 ± 0.2 kg, p < 0.001). Only one participant was classified as having low muscle mass without AMD processing, but this came to four after AMD processing. LM assessment in individuals who had TKR could be significantly different according to the use of AMD.
Non-invasive monitoring of T cell differentiation through Raman spectroscopy
Authors: Pavillon Nicolas , Smith Nicholas I. 
Published: February 2023

AbstractThe monitoring of dynamic cellular behaviors remains a technical challenge for most established techniques used nowadays for single-cell analysis, as most of them are either destructive, or rely on labels that can affect the long-term functions of cells. We employ here label-free optical techniques to non-invasively monitor the changes that occur in murine naive T cells upon activation and subsequent differentiation into effector cells. Based on spontaneous Raman single-cell spectra, we develop statistical models that allow the detection of activation, and employ non-linear projection methods to delineate the changes occurring over a several day period spanning early differentiation. We show that these label-free results have very high correlation with known surface markers of activation and differentiation, while also providing spectral models that allow the identification of the underlying molecular species that are representative of the biological process under study.
Development of the automated temperature control system of the main gas pipeline
Authors: Fetisov Vadim , Ilyushin Yury V. , Vasiliev Gennadii G. , Leonovich Igor A. , Müller Johannes , Riazi Masoud , Mohammadi Amir H. 
Published: February 2023

AbstractThis article presents the results of a numerical experiment and an analysis of temperature fields (coolers for gas) using cooling elements in the case study gas pipeline. An analysis of the temperature fields demonstrated several principles for the formation of a temperature field, which indicates the need to maintain a relative temperature for gas pumping. The essence of the experiment was to install an unlimited number of cooling elements on the gas pipeline. The purpose of this study was to determine at what distance it is possible to install cooling elements for the optimal gas pumping regime, regarding the synthesis of the control law and the determination of the optimal location and assessment of control error depending on the location of the cooling elements. The developed technique allows for the evaluation of the developed control system's regulation error.