bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Dietary Patterns on Gastrointestinal Symptoms among Children with Autistic Spectrum Disorder
Authors: Al-Joburi Lina N Sajad , Hasan Abdul Mahdi A Hasan , Al-Aaraji Ameera Jasim 
Published: June 2023

Objective(s): to determine the effect of dietary pattern on gastrointestinal symptoms among children with autistic spectrum disorder. Methodology: A descriptive correlational study designed to determine the effect of dietary pattern on gastrointestinal symptoms among children with autistic spectrum disorder for the period of October 20th 2021 to May 15th 2023. A nonprobability, purposive , sample of (150) parent of children with autistic spectrum disorder is selected for the purpose of the study. All parents have signed consent form for their agreement to participate in the study and to ensure confidentiality, as well as to confirm the ethical considerations. A developed questionnaire is used for the purpose of the current study. The questionnaire is comprised of (4) parts that include: parents’ socio-demographic characteristics (15) item; children’s socio-demographic characteristics (12) item; dietary patterns (16) item and gastrointestinal symptoms (14) item. Content validity of the questionnaire is determined through panel of (20) expert in the fields of Pediatric Nursing, Pediatric Medicine and Community Health Nursing. Internal consistency reliability of the questionnaire is obtained through the use of split-half technique. Cronbach alpha correlation coefficient is computed for such reliability; (r=0.81) for dietary patterns and (r=0.78) for gastrointestinal symptoms. Data are collected through the use of the study questionnaire. Data are analyzed through the use of the descriptive statistical data analysis approach of frequency, percent, mean, standard deviation, total scores and range and inferential statistical data analysis approach of multiple linear regressions. Results: The study findings indicate that children have experienced problems with their dietary patterns and such patterns have highly significant effect on gastrointestinal symptoms among children with autistic spectrum disorder evidenced by highly significant p-value of (0.001). Conclusion: The study confirms that there is highly significant effect between dietary patterns and gastrointestinal symptoms among children with autistic spectrum disorder.
Perceived Disability-Based Discrimination in Health Care for Children With Medical Complexity
Authors: Ames Stefanie G. , Delaney Rebecca K. , Houtrow Amy J. , Delgado-Corcoran Claudia , Alvey Justin , Watt Melissa H. , Murphy Nancy 
Published: June 2023

BACKGROUND AND OBJECTIVES
Disability-based discrimination in health care can lead to low quality of care, limited access to care, and negative health consequences. Yet, little is known regarding the experiences of disability-based discrimination in health care for children with medical complexity and disability. An understanding of disability-based discrimination in pediatrics is needed to drive change and improve care.

METHODS
We conducted in-depth, semistructured interviews with caregivers of children with medical complexity and disability. Participants were purposefully recruited through national advocacy and research networks. Interviews were conducted via video conferencing, recorded, and transcribed. Data collection and analysis occurred iteratively. An inductive thematic analysis approach with constant comparison methods was used to identify themes that form a conceptual framework of disability-based discrimination in health care.

RESULTS
Thirty participants from diverse backgrounds were interviewed. Six themes emerged, forming a conceptual framework of disability-based discrimination in health care. Three themes described drivers of discrimination: lack of clinician knowledge, clinician apathy, and clinician assumptions. Three themes described manifestations of discrimination: limited accessibility to care, substandard care, and dehumanization.

CONCLUSIONS
Children with medical complexity may face disability-based discrimination in health care. Themes describing the drivers and manifestations of discrimination offer a conceptual framework of disability-based discrimination. Understanding the drivers and acknowledging perceived manifestations can provide insight into improving patient care for children with disabilities.
Upaya meningkatkan gizi masyarakat melalui program keluarga sadar gizi (kadarzi)
Authors: Paramita Farah , Sulistyorini Anita , Katmawanti Septa , Septiani Selsa Tri , Saputri Lorenza Arinda , Ramadhani Shirin , Hasanah Annisa' Mufi Aktul , Wahyuni Oktavia Sri 
Published: June 2023

Permasalahan gizi masih menjadi masalah yang tidak pernah usai. Program KADARZI (Keluarga Sadar Gizi) merupakan salah satu komitmen pemerintah untuk memberdayakan keluarga agar mampu menyelesaikan permasalahan kesehatan sedini mungkin. Desa Petungsewu memiliki komoditas unggulan yaitu perkebunan jeruk. Tujuan dari kegiatan ini ialah untuk meningkatkan gizi masyarakat desa melalui program KADARZI dengan memanfaatkan bahan pangan lokal berupa jeruk dan menggunakan media booklet. Metode yang digunakan adalah kegiatan pelatihan terstruktur. Populasi dalam kegiatan ini merupakan semua Ibu yang memiliki balita dengan total sampel 20 responden. Instrumen yang digunakan untuk menilai pengetahuan adalah berupa kuesioner yang diisi secara mandiri oleh peserta. Kegiatan ini dilakukan pada Agustus 2022 di Desa Petungsewu, Kabupaten Malang dengan melalui berbagai tahap kegiatan, seperti pemberian pre-test, pemberian booklet, edukasi dan sharing session, lomba kreasi makanan (makanan keluarga dan MP-ASI) yang memanfaatkan bahan pangan lokal, dan pemberian post-test pada akhir kegiatan. Dari hasil analisis dapat diketahui bahwa dengan dilakukannya intervensi berupa edukasi gizi untuk balita dan keluarga dengan bantuan booklet dapat meningkatkan pengetahuan responden, yakni dengan persentase 95% (19 responden) yang termasuk ke dalam kategori baik.
Comparative analysis of collagen-1 amongst locally-farmed tilapia samples as potential xenograft for partial-thickness burns
Authors: Siriruck Pinyapat , Pongpoon Woraphat 
Published: June 2023

Background: Tilapia farming is amongst the most lucrative in terms of yield and return of investments in the aquaculture industry in Thailand. The sustainable supply of tilapia (Oreochromis spp.) can be exploited to reconsider the fish species as a huge potential for Thailand’s medical sector, particularly on xenograft as an innovative treatment for burns.
Methods: Collagen content quantification by high-performance liquid chromatography (HPLC) method is done on two samples: Chitralada I tilapia (Thai locally cultured strain of Oreochromis niloticus) and pink tilapia (commercially cultured strain by Charoen Pokphand Foods PCL) skin to compare the amount of type I collagen (COL-I) by measuring one of its major amino acids, hydroxyproline, with Nile tilapia skin which has been used as xenograft in Brazil.
Results: The results showed that there is no significant difference in the amount of hydroxyproline amongst the two strains. Chitralada I tilapia sample contains 9.01 g/100g (9.01%) and pink tilapia sample contains 18.55 g/100g (18.55%) of hydroxyproline respectively.
Conclusions: Since there are minor differences between the amount of hydroxyproline in Thai locally-farmed tilapia and Nile tilapia; therefore, Thai locally-farmed tilapia xenograft can be a possible choice for burn treatment.
Awareness and utilization of physiotherapy services in management of people living with HIV among health care workers
Authors: Uchenna Eleje Chiedozie 
Published: June 2023

Background: Physiotherapy is one of multidisciplinary teams that has demonstrated efficacy in HIV care/management. Irrespective of the evidence established on the efficacy of physiotherapy intervention on HIV management, there seem to be poor utilization of physiotherapy services by PLWHA. The aim of this study is to assess the healthcare providers’ awareness on the role of physiotherapy in HIV management and the possible factors affecting the utilization of services by the healthcare providers.
Methods: The study is a cross-sectional descriptive study. Ethical approval was obtained from the University of Nigeria Teaching Hospital Health Research Ethics Committee Ituku-Ozalla (UNTH). A self-structured 20-item questionnaire was distributed to 75 healthcare providers (56 females and 19 males) working within Enugu metropolis. Data were summarized with descriptive statistics of frequency and percentages.
Results: Majority perceived physiotherapist not knowledgeable in the management of HIV 49(65%) and PLWHA uninformed on the role of Physiotherapy in their management 68(91%). Also, majority of the respondent perceived been ignorant of the type of physiotherapy services available in HIV management role affected its utilization 55(75%) and attributed poor awareness creation by physiotherapists 57(76%) as a limiting factor.
Conclusions: Poor awareness creation by physiotherapist for PLWHA among Healthcare providers, poor knowledge of the healthcare providers regarding the physiotherapy care available in HIV management are major barriers to utilization of physiotherapy services in HIV management.
USING FOLK GAME-BASED AND BODY TRAINING TECHNOLOGIES IN MODERN EDUCATION IN EUROPEAN COUNTRIES
Authors: Tsybanyuk Oleksandra , Komisaryk Mariia , Kuznietsova Kateryna , Mishkulynets Olena , Chuyko Halyna 
Published: June 2023

Modern education involves dynamic physical and spiritual improvement of children and youth. The tendencies of its development should be aimed at overcoming the mutual physical, emotional and spiritual alienation of education seekers, ensuring the implementation of the creative component in the educational process. At the same time, the increased attention in physical education in European institutions nowadays is paid to the historical, cultural and humanitarian direction, while an increase in the importance of folk game-based body training tools and methods is observed. The purpose of the academic paper is to clarify the features and key tendencies in using folk game-based body training technologies in the educational process of European countries. During the research, the analytical and bibliographic method was used to study the scientific literature on using body training technologies in modern education. Along with this, induction, deduction, analysis, synthesis of information, system-structural, comparative, logical-linguistic methods, abstraction, and idealization were applied to study and process the data. Moreover, the research authors conducted the questionnaire in online mode to practically clarify the most significant issues related to the organization of the educational process in European countries.Â Based on the research results, the primary and most important theoretical aspects of the issue of applying folk game-based body training technologies in educational institutions of European countries were established, and the standpoints of scientists and heads of educational institutions regarding the key aspects of this issue were also investigated.
Characterization of collagen from Java barb (Barbonymus gonionotus) skin and its effect on selected properties of yogurt
Authors: A. Prihanto Asep , Nursyam Happy , D. Jatmiko Yoga , Nur H. Oslan Siti , A. Jaziri Abdul , Febriantoni  , D. Maudy Karina 
Published: June 2023

Wastes of Barbonymus gonionotus (Java barb) skin can be processed as collagen as a food additive. Yogurt is a functionaldrink that has gained attention. This study aimed to characterize yogurt added with collagen from Java barb skin. The solutions used to extract the collagen were (A) 1:10 (w/v) for 24 h, (B) 1:20 (w/v) for 24 h, (C) 1:10 (w/v) for 36 h, and (D) 1:20 (w/v) for 36 h. The obtained collagen was added to yogurt at concentrations of 1%, 2%, and 3%. The yogurt was then examined for its protein content, pH, and titratable acidity. The highest yield of collagen was obtained from treatment D, with a value of 52.54% ± 0.94%. All the extracted collagens had triple-helix structures. The presence of α1 and α2 was also confirmed by sodium dodecyl-sulfate polyacrylamide gel electrophoresis, and the amino acid patterns were found to be either Gly-Pro-Ala or Gly-Pro-Arg. The addition of collagen to yogurt at a concentration of 3% produced a significant increase in protein content (3.82%). In comparison, pH and titratable acidity did not show any significant changes. However, the titratable acidity at a collagen concentration of 3% showed a small increase of 1.14% ± 0.71% at the end of fermentation. In conclusion,collagen was successfully extracted with relatively high yields, and collagen-added yogurt met industry standards. The addition of collagen at a concentration of 3% increased the protein content of yogurt and only had a slight effect on its selected characteristics.
Talar OsteoPeriostic Grafting from the Iliac Crest (TOPIC)
Authors: Dahmen Jari , Rikken Quinten , Stufkens Sjoerd A.S. , Kerkhoffs Gino M.M.J. 
Published: June 2023

Background:
Press-fit Talar OsteoPeriostic grafting from the Iliac Crest (TOPIC) is a novel technique for the treatment of large osteochondral lesions of the talus. The purpose of the present study was to prospectively evaluate the 2-year clinical outcomes for patients with medial osteochondral lesions of the talus that were treated with the TOPIC procedure.

Methods:
Forty-three patients were prospectively assessed before and 24 months after the TOPIC procedure. All procedures were performed through a medial distal tibial osteotomy. Clinical assessment preoperatively and at 24 months of follow-up included determination of the Numeric Rating Scale (NRS) scores for pain during walking (primary outcome), at rest, during running, and during stair-climbing. The Foot and Ankle Outcome Score (FAOS) and the Mental Component Summary (MCS) score and Physical Component Summary (PCS) score of the Short Form-36 (SF-36) were also assessed. A computed tomography (CT) scan was performed 12 weeks postoperatively to assess union of the distal tibial osteotomy site and at 1 and 2 years postoperatively to assess consolidation of the graft as well as cyst development in the graft.

Results:
All enrolled patients were available for follow-up. The median NRS score for pain during walking improved from 7 points preoperatively to 2 points at 2 years postoperatively (p < 0.001). All other NRS scores for pain improved significantly. All FAOS subscale scores improved significantly, including those for pain (from 53 to 75), symptoms (from 50 to 61), activities of daily living (from 68 to 88), sports (from 30 to 55), and quality of life (from 19 to 38). The SF-36 PCS score improved from 43 to 48 (p < 0.001), and the MCS score changed from 28 to 26 (p > 0.05). There was a 100% rate of union of the osteotomy site at the distal tibia and 100% of the grafts showed consolidation at 1 and 2 years postoperatively.

Conclusions:
The TOPIC procedure for large osteochondral lesions of the medial talar dome is an effective technique that resulted in significant improvement exceeding the minimal clinically important difference in pain scores (primary outcome) as well as in other outcomes, with 100% consolidation of the grafts.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
A Comparative in Vitro Study of Pb Tolerance in Three Sugarcane Genotypes
Authors: saleem yasmeen , Ali Aamir , Naz Shagufta , Jamil Muhammad 
Published: June 2023

Abstract
Heavy metal accumulation in agriculture land is one of the major agriculture challenges affecting the crop production and threatens the food safety. Comparative study for Lead (Pb) tolerance in three sugarcane (Saccharum officinarum L.) genotypes was carried out under in vitro conditions. Fresh weight, dry weight, callus morphology, shoot morphology, protein contents, catalase, superoxide dismutase and peroxidase, ascorbic acid contents, relative growth rate, stress tolerance index, Pb contents, bioconcentration factor were compared at 6 different concentrations of Pb (0mM, 0.1, 0.2, 0.3, 0.4, 0.5, 1mM). Lead affected the callus and its regeneration in all three genotypes while root regeneration did not affect considerably. All genotypes significantly vary at each treatment and parameter except BCF and protein contents. Genotype YT-53 proved most resistant toward Pb stress while CP-77400 was next to it and NSG-59 showed least resistance toward Pb stress. Most resistant genotypes can be used in heavy metal effected area for better yield and phytoremediation in Pb affected soil and in other breeding programs.
Frailty over the rainbow: a cross-sectional study on LGBT+ adults over fifty
Authors: Melo Leonardo Rabelo , Crenitte Milton Roberto Furst , Filho Wilson Jacob , Avelino-Silva Thiago Junqueira 
Published: June 2023

Abstract
Background
Frailty is associated with several adverse outcomes in older adults, including functional dependency, hospitalizations, and death. However, it has not been determined whether older LGBT + individuals are at a higher risk of frailty than the overall population. Therefore, we aimed to investigate the prevalence of frailty in older LGBT + adults, comparing them with heterosexual-cisgender individuals.
Methods
A cross-sectional study involving Brazilians aged 50 and over was performed. They were invited to answer an anonymous online-based survey between August 2019 and January 2020. The survey was widely distributed in neighborhood associations, day centers, non-governmental organizations, and social media. Participants were encouraged to forward information about the study to their contacts. Those who identified as homosexual, bisexual, pansexual, non-heterosexual, transgender, travesti, or non-binary were grouped as LGBT+; cisgender and heterosexual participants as non-LGBT+. Frailty was measured using the FRAIL scale, and participants were categorized as robust, prefrail, or frail. We used generalized ordered logistic models to examine the adjusted association between being LGBT + and frailty, according to age group and sex.
Results
We included 6,693 participants with a median age of 60 years. Overall, 1332 were LGBT+ (19.9%), and 5361, non-LGBT+ (80.1%). Pre-frailty or frailty was found in 656 (49%) LGBT + participants and 2,460 (46%) non-LGBT + participants (p = .03). In our multivariable analyses, we found that being LGBT + was independently associated with frailty in female participants aged ≥ 50 years (OR = 1.52, 95%CI = 1.08–2.13, p = .02) and in male participants aged ≥ 60 years (OR = 2.83, 95%CI = 1.41–5.69, p = .004). Non-cisgender participants were also more likely to be frail than cisgender participants (OR = 2.21, 95%CI = 1.42–3.42, p < .001).
Conclusion
Being LGBT + was independently associated with frailty in female adults over 50 and males over 60. More research in this area and inclusive government policies are needed to promote healthy aging and address the needs of the LGBT + population.
Dynamics and embedded solitons of stochastic quadratic χ(2) and cubic χ(3) nonlinear susceptibilities with multiplicative white noise in the Itô sense
Authors: Li Zhao , Peng Chen 
Published: June 2023

Abstract
The main purpose of this paper is to study the dynamics and embedded solitons of stochastic quadratic χ(2) and cubic χ(3) nonlinear susceptibilities in the Itˆo sense. Firstly, two-dimensional dynamics system and its perturbation system are obtained by using travelling wave transformation. Secondly, phase portraits of two-dimensional dynamics system are plotted. What’s more, chaotic behaviors, two-dimensional phase portraits, three-dimensional phase portraits and sensitivity of the perturbation system are analyzed by using the Maple software. Finally, the embedded solitons of stochastic quadratic χ(2) and cubic χ(3) nonlinear susceptibilities are obtained. Moreover, three-dimensional and two-dimension of stochastic quadratic χ(2) and cubic χ(3) nonlinear susceptibilities are plotted.
Mentalization and Self-compassion as Protective Factors for Parental Burnout among Parents with Disabled Children
Authors: Manshadi Zobeydeh Dehghan , Fathi Elham , Manshadi Mohammad Amin Dehghan , Keyvanmanesh Nahid 
Published: June 2023

Abstract
Parenting is a complex and stressful activity, and parents with disabled children suffer even more stress, causing fatigue and burnout. This study aimed to investigate whether mentalization and self-compassion could protect parents from burnout among parents with disabled children and what is the prevalence of parental burnout among such parents. A total of 911 parents of children with special needs completed the Parental Burnout Inventory (PBI), Reflective Functioning Questionnaire (RFQ), and Self-Compassion Scale (SCS). The frequency, Chi-square, and Generalized Additive Models (GAMs) by R_v4.0.3 using the mgcv package were utilized to analyze data. Among parents with disabled children, 1.6% experienced severe burnout, while 26.8% experienced moderate burnout. In addition, mentalization and self-compassion were associated with parental burnout. Self-compassion and hyper-mentalizing were associated with less parental burnout, whereas hypo-mentalizing was associated with more burnout. Among Iranian parents who are permanent caregivers to a disabled child, self-compassion and hyper-mentalizing play protective roles, whereas hypo-mentalizing plays a risky role in parental burnout.
Symptoms of SARS-CoV-2 infection and vaccine status of sixty-seven adult patients affected by inherited metabolic diseases: a phone survey.
Authors: BRODOSI LUCIA , Stecchi Michele , Mita Dorina , Marchignoli Francesca , Guarneri Valeria , Agnelli Giulio , Osti Valentino , Perazza Federica , Sacilotto Federica , Pession Andrea , Pironi Loris 
Published: June 2023

Abstract
Background: The Covid pandemic seems to have had several detrimental effects on managing patients affected by inherited metabolic diseases (IMD), although published data about the impact of COVID-19 on patients suffering from IMD are very scarce. The scope of our work was to evaluate adherence to the vaccination plan, the side effects experienced by our adult IMD patients, and the symptoms of the SARS-CoV-2 infection.
Results: sixty-seven patients agreed to respond to a phone interview. The mean age was 36.5 (±11,6 SD). Regarding the vaccination campaign, fifty-five patients (82%) joined it, of whom ten have received two doses and the remaining forty-five, three. Forty-two patients (76%) reported adverse events following vaccination, the most frequent being local reaction, fever, and asthenia, which lasted an average of two days and resolved without sequelae. Regarding SARS-CoV-2 infection, twenty-seven out of sixty-seven patients (40%) have tested positive for the virus; seven of them were not vaccinated at the time of infection; on the other hand, twenty had already had at least two doses.
Regarding the prevalence of long-Covid, as many as 12 patients (44%) reported symptoms that persisted after the nasopharyngeal swab tested negative and lasted an average of 81 (±74 SD) days. There were no statistically significant differences in BMI of patients who contracted the infection and patients who did not (25.15 vs 25.20, p=.861), between those who had adverse reactions to the vaccine and those who did not (24.40 vs 25.75, p=.223), between those who had long Covid and those who did not (25.9 vs 27.7, p=.183). No relation was observed between metabolic inherited disease, SARS-CoV-2 infection symptoms and adverse vaccine reactions.
Conclusions: The data indicate that IMD patients adhered to the vaccination plan comparably to the general Italian population. Adverse events to the vaccine were negligible. SARS-CoV-2 infection, which occurred in most cases after receiving at least two doses of the vaccine, did not cause serious symptoms and never required hospitalisation. A non-negligible share of patients suffered from long Covid symptoms.