bluuebunny/crossref_metadata_2025_split huggingface dataset:
“I remember the attack”: a pilot study investigating flashbulb memory in individuals with schizophrenia
Authors: Altman Rosalie Ariane Eva , Bortolon Catherine , El Haj Mohamad , Capdevielle Delphine , Raffard Stéphane 
Published: February 2023

AbstractFlashbulb memories are autobiographical memories for important and emotional events, which have the particularity of being at the intersection of personal and public events. Autobiographical memory impairments are highly prevalent in schizophrenia, a psychiatric condition intrinsically linked to self-disorders. Thus, we aimed to evaluate flashbulb and event memory functioning in individuals with schizophrenia. Twenty-four individuals diagnosed with schizophrenia and 25 control participants were tested on a flashbulb memory questionnaire about the July 14th, 2016, Nice (France) terrorist attack, including questions on flashbulb and event memory, certainty, vividness, rehearsal, emotion, novelty, consequentiality, implication, and importance. Participants also underwent cognitive assessments. Analysis showed lower scores for both flashbulb and event memories in patients compared to control participants. Subjective ratings of the phenomenological characteristics of flashbulb memory were similar between the two groups overall. However, individuals with schizophrenia reported having higher levels of emotion when they first learned about the attack compared to the control group. Our results replicate findings of impaired autobiographical memory functioning in schizophrenia and extend these findings to public events. Our findings also indicate that flashbulb memories may lead to substantial contextual recall in schizophrenia patients and that collective memories, such as a terrorist attack, can have a profound emotional impact on patients.
Determinants of mindful parenting: a cross-cultural examination of parent and child reports
Authors: Acet Pinar , Oliver Bonamy R. 
Published: February 2023

AbstractBased on Belsky’s process of parenting model and its recent update, the present study aims to explore multiple determinants of mindful parenting (i.e., parents’ psychological distress, child negative emotionality, and parental social support) across the UK and Türkiye using a multi-informant approach and multiple-group path analysis. We considered both parents’ and children’s perceptions of mindful parenting to obtain a complete picture of the mindful parenting process within families. Parents and their children aged 11–16 years were recruited in the UK (N = 101, Mchild age = 13.06 years, SDchild age = 1.64 years) and Türkiye (N = 162, Mchild age = 13.28 years, SDchild age = 1.65 years). Multiple-group path analysis revealed that both parent and child perspectives of mindful parenting are multiply determined. Parental psychological distress mediated the associations of child negative emotionality and social support with mindful parenting in both cultures. However, child negative emotionality was a direct determinant of mindful parenting in the UK only. Overall, our study shed light on both individual and cultural differences in the mindful parenting process. Limitations of the current research and recommendations and implications for future mindful parenting research and practices were discussed.
Characterization of housing stock for energy retrofitting purposes in Spain
Authors: González-Caballín Sánchez Juan M. , Meana-Fernández A. , Ríos-Fernández J. C. , Gutiérrez Trashorras A. J. 
Published: February 2023

AbstractEnergy saving in existing buildings is of vital importance. In this work, the characterization of housing stock in Spain for energy retrofitting purposes has been performed. The regulations in force when the existing stock was constructed (1980–2007) were considered to model the envelope and thermal systems of single-family and block housing. Building energy consumption and CO2 emissions were estimated for each type of dwelling and location, ranging from 44.2 to 130.6 kWh/(m2·year) (13.6–32 kg CO2/(m2·year)) for multi-family homes, and 85.5 to 213.5 kWh/(m2·year) (17.1–45.2 kg CO2/(m2·year)) for single-family homes. A global picture of the energy performance and emissions for 13 different climate zones was obtained with a total of 504 simulations. Retrofitting of the envelope allowed the reduction of consumption and emissions from 37.7% to 58%, depending on the climate zone. Energy consumption per square meter in block housing was lower than in single-family housing; nevertheless, single-family houses responded more effectively to energy improvement actions. Finally, non-renewable primary energy savings seem a better indicator of the improvement by retrofitting than the energy label. The building models designed in this work may serve as a reference for subsequent research concerning energy retrofitting and energy savings of housing stock.
State Behaviour in Cyberspace: Normative Development and Points of Contention
Authors: Lahmann Henning 
Published: February 2023

AbstractThe increasing use of digital technologies in cyberspace in the context of international conflicts has put pressure on the existing legal framework of international law. After progress in terms of norm development and clarification could be achieved through multilateral processes at the United Nations, Russia’s invasion of Ukraine cast doubt on the possibility of further breakthroughs. In light of this development, unilateral declarations of legal positions by states will gain further relevance.
Parentage-based tagging and parentage analyses of stocked sea trout in Vistula River commercial catches
Authors: Wąs-Barcz Anna , Bernaś Rafał 
Published: February 2023

AbstractThe longest Baltic River, the Vistula, historically hosted numerous sea trout populations. However, dam construction in the twentieth century drastically reduced the spawning migration rate. Reduced natural reproduction has resulted in a population collapse and, consequentially, a substantial reduction in catches. In response, like other Baltic countries, Poland has initiated an intensive stocking program, mainly involving smolt. Initially, stocking was conducted primarily with offspring of sea trout caught during spawning migration. Currently, due to difficulties in obtaining fish, most stocking involves fish from breeding stocks. Therefore, determining the proportion of fish derived from stocking has become an important issue. Experiments based on traditional tagging did not provide sufficient material for analysis; hence, we decided to use genetic methods based on analysis of relatedness. In this study, we performed parentage-based tagging and an analysis of the origins of parent animals used for artificial spawning in 2013, and offspring returning to the Vistula in subsequent years. We based the analysis on three different algorithms and compared the results, showing that the presented methods were effective for estimating mass stocking success. The study also indicated that a certain level of natural reproduction in the Vistula continues to occur. The proportion of sea trout from spawning in 2013 in Vistula sea trout catches from 2017 to 2018 was approximately 30%.
In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression
Authors: Montero-Calle Ana , López-Janeiro Álvaro , Mendes Marta L. , Perez-Hernandez Daniel , Echevarría Irene , Ruz-Caracuel Ignacio , Heredia-Soto Victoria , Mendiola Marta , Hardisson David , Argüeso Pablo , Peláez-García Alberto , Guzman-Aranguez Ana , Barderas Rodrigo 
Published: February 2023

Abstract
Background
Endometrial cancer (EC) is the most common cancer of the female reproductive organs. Despite the good overall prognosis of most low-grade ECs, FIGO I and FIGO II patients might experience tumor recurrence and worse prognosis. The study of alterations related to EC pathogenesis might help to get insights into underlying mechanisms involved in EC development and progression.

Methods
Core tumoral samples were used to investigate the role of C1GALT1 in EC by immunohistochemistry (IHC). ECC-1 cells were used as endometrioid EC model to investigate the effect of C1GALT1 depletion using C1GALT1 specific shRNAs. SILAC quantitative proteomics analyses and cell-based assays, PCR, qPCR, WB, dot-blot and IHC analyses were used to identify, quantify and validate dysregulation of proteins.

Results
Low C1GALT1 protein expression levels associate to a more aggressive phenotype of EC. Out of 5208 proteins identified and quantified by LC-MS/MS, 100 proteins showed dysregulation (log2fold-change ≥ 0.58 or ≤-0.58) in the cell protein extracts and 144 in the secretome of C1GALT1 depleted ECC-1 cells. Nine dysregulated proteins were validated. Bioinformatics analyses pointed out to an increase in pathways associated with an aggressive phenotype. This finding was corroborated by loss-of-function cell-based assays demonstrating higher proliferation, invasion, migration, colony formation and angiogenesis capacity in C1GALT1 depleted cells. These effects were associated to the overexpression of ANXA1, as demonstrated by ANXA1 transient silencing cell-based assays, and thus, correlating C1GALT and ANXA1 protein expression and biological effects. Finally, the negative protein expression correlation found by proteomics between C1GALT1 and LGALS3 was confirmed by IHC.

Conclusion
C1GALT1 stably depleted ECC-1 cells mimic an EC aggressive phenotype observed in patients and might be useful for the identification and validation of EC markers of progression.
Development of artificial neural network models to predict the PAMPA effective permeability of new, orally administered drugs active against the coronavirus SARS-CoV-2
Authors: Gousiadou Chrysoula , Doganis Philip , Sarimveis Haralambos 
Published: February 2023

AbstractResponding to the pandemic caused by SARS-CoV-2, the scientific community intensified efforts to provide drugs effective against the virus. To strengthen these efforts, the “COVID Moonshot” project has been accepting public suggestions for computationally triaged, synthesized, and tested molecules. The project aimed to identify molecules of low molecular weight with activity against the virus, for oral treatment. The ability of a drug to cross the intestinal cell membranes and enter circulation decisively influences its bioavailability, and hence the need to optimize permeability in the early stages of drug discovery. In our present work, as a contribution to the ongoing scientific efforts, we employed artificial neural network algorithms to develop QSAR tools for modelling the PAMPA effective permeability (passive diffusion) of orally administered drugs. We identified a set of 61 features most relevant in explaining drug cell permeability and used them to develop a stacked regression ensemble model, subsequently used to predict the permeability of molecules included in datasets made available through the COVID Moonshot project. Our model was shown to be robust and may provide a promising framework for predicting the potential permeability of molecules not yet synthesized, thus guiding the process of drug design.
Quantitative Estimation of Pipeline Slope Disaster Risk in China
Authors: Yan Yan , Zhou Jiaojiao , Xie Cheng , Yin Shuyao , Hu Sheng , Wang Renchao 
Published: February 2023

AbstractChina’s economic development is closely related to oil and gas resources, and the country is investing heavily in pipeline construction. Slope geological hazards seriously affect the long-term safe operation of buried pipelines, usually causing pipeline leakage, property and environmental losses, and adverse social impacts. To ensure the safety of pipelines and reduce the probability of pipeline disasters, it is necessary to predict and quantitatively evaluate slope hazards. While there has been much research focus in recent years on the evaluation of pipeline slope disasters and the stress calculation of pipelines under hazards, existing methods only provide information on the occurrence probability of slope events, not whether a slope disaster will lead to pipeline damage. Taking the 2015 Xinzhan landslide in Guizhou Province, China, as an example, this study used discrete elements to simulate landslide events and determine the risk level and scope for pipeline damage, and then established a pipe-soil coupling model to quantitatively evaluate the impact of landslide hazards for pipelines in medium- and high-risk areas. The results provide a reference for future pipeline disaster prevention and control.
Invariant measures and global well-posedness for a fractional Schrödinger equation with Moser-Trudinger type nonlinearity
Authors: Casteras Jean-Baptiste , Monsaingeon Léonard 
Published: February 2023

AbstractIn this paper, we construct invariant measures and global-in-time solutions for a fractional Schrödinger equation with a Moser–Trudinger type nonlinearity $$\begin{aligned} i\partial _t u= (-\Delta )^{\alpha }u+ 2\beta u e^{\beta |u|^2} \qquad \text{ for }\qquad (x,t)\in \ M\times \mathbb {R}\end{aligned}$$

i

∂
t

u
=

(
-
Δ
)

α

u
+
2
β
u

e

β
|
u
|

2

for

(
x
,
t
)

∈

M
×
R

on a compact Riemannian manifold M without boundary of dimension $$d\ge 2$$

d
≥
2

. To do so, we use the so-called Inviscid-Infinite-dimensional limits introduced by Sy (’19) and Sy and Yu (’21). More precisely, we show that if $$s>d/2$$

s
>
d
/
2

or if $$s\le d/2$$

s
≤
d
/
2

and $$s\le 1+\alpha $$

s
≤
1
+
α

, there exists an invariant measure $$\mu ^{s}$$

μ
s

and a set $$\Sigma ^s \subset H^s$$

Σ
s

⊂

H
s

containing arbitrarily large data such that $$\mu ^{s}(\Sigma ^s ) =1$$

μ
s

(

Σ
s

)

=
1

and that (E) is globally well-posed on $$\Sigma ^{s}$$

Σ
s

. In the case when $$s>d/2$$

s
>
d
/
2

, we also obtain a logarithmic upper bound on the growth of the $$H^r$$

H
r

-norm of our solutions for $$r<s$$

r
<
s

. This gives new examples of invariant measures supported in highly regular spaces in comparison with the Gibbs measure constructed by Robert (’21) for the same equation.
Brain Patents as a Legal or Societal Challenge?
Authors: Spranger Tade Matthias 
Published: February 2023

AbstractPatents relating to the human brain and its functions regularly fulfil the general patent requirements. In some cases, however, the inventions in question reveal considerable risks for the rights of individuals, but also for society as such, which have a hitherto unknown dimension and which have not been discussed so far. Due to the limited scope of application of the ordre public clause, patent law is fundamentally not in a position to respond adequately to the challenges that exist here. The ratio of patent law and the lack of resources and also, above all, competence of the patent offices for a more extensive ethico-legal analysis mean that patent law is not the right setting for dealing with the existing challenges. Instead, the international organisations responsible for the protection of human rights and their relevant bodies are in particular demand here, although they have so far been unaware of the difficulties that are evident in the area of brain patents. What is needed is the development and establishment of mechanisms that enable the flagging and communication of critical patents, so that the responsible bodies are enabled to fulfil their tasks.
Deformation characteristics and inertial effect of complex aluminum alloy sheet part under impact hydroforming: experiments and numerical analysis
Authors: Xia Liang-Liang , Zhang Shi-Hong , Xu Yong , Chen Shuai-Feng , Khina Boris B. , Pokrovsky Artur I. 
Published: February 2023

AbstractImpact hydroforming (IHF), as a novel sheet metal forming technology with the advantages of high strain rate forming and flexible liquid loading, is highly suitable for efficiently manufacturing aluminum complex-shaped sheet parts. In this paper, deformation characteristics of complex sheet parts under IHF are systematically investigated. The mechanical properties of 2024 aluminum alloy under a wide range of strain rates (10−3 s−1–3.3×103 s−1) were studied. It indicated that the elongation of 2024 aluminum alloy was improved by 116.01% under strain rates of 3.306 × 103 s−1, referring to 10−3 s−1. Further, a complex-shaped part with symmetrical and asymmetrical structures was selected. The deformation characteristics of sheet and role of inertial effect under IHF were investigated with well-developed solid–liquid coupling finite element (SLC-FE) model with high accuracy. Differentiating deformation tendency is found for symmetrical structure with notably prior deformation at central zone, showing a “bulging” profile at initial forming stage. Whereas, synchronous deformation is presented for asymmetrical structure with a “flat” profile. Additionally, distinctive inertial effect was observed at different positions change for both symmetrical and asymmetrical structures, in which lower values were resulted at their central regions. Meanwhile, the inertial effect evolved with the impacting speed. Specially, larger difference of inertial effect was observed with increasing impacting speed.
Power supply arm protection scheme of high-speed railway based on wide-area current differential
Authors: Lin Guosong , Hong Bin , Wu Zefang , Fu Xuguo 
Published: February 2023

AbstractWhen fault occurs on cross-coupling autotransformer (AT) power supply traction network, the up-line and down-line feeder circuit breakers in the traction substation trip at the same time without selectivity, which leads to an extended power failure. Based on equivalent circuit and Kirchhoff’s current law, the feeder current characteristic in the substation, AT station and sectioning post when T–R fault, F–R fault, and T–F fault occur are analyzed and their expressions are obtained. When the traction power supply system is equipped with wide-area protection measurement and control system, the feeder protection device in each station collects the feeder currents in other two stations through the wide-area protection channel and a wide-area current differential protection scheme based on the feeder current characteristic is proposed. When a short-circuit fault occurs in the power supply arm, all the feeder protection devices in each station receive the feeder currents with time stamp in other two stations. After data synchronous processing and logic judgment, the fault line of the power supply arm can be identified and isolated quickly. The simulation result based on MATLAB/Simulink shows that the power supply arm protection scheme based on wide-area current differential has good fault discrimination ability under different fault positions, transition resistances, and fault types. The verification of measured data shows that the novel protection scheme will not be affected by the special working conditions of the electrical multiple unit (EMU), and reliability, selectivity, and rapidity of relay protection are all improved.
Typhoon field construction and wind-induced wave model optimization based on topographic parameters
Authors: Chen Cheng , Peng Chen , Xiao Hong , Wei Minjian , Wang Tingyu 
Published: February 2023

AbstractIn recent years, most of the research on typhoon in Fujian Province of China has stayed in the typhoon wave simulation under the influence of wind fields. In order to study the influence of land terrain on typhoon wave fields, the terrain height parameters are introduced into the wind field simulation through the third-generation typhoon wave numerical model. The numerical simulation results of the model are verified and analyzed by referring to the data of significant wave height and wind speed of typhoon Fung-wong (200808) and typhoon Jangmi (200815) when it is across Taiwan Island. The results show that the relative error of the maximum wind speed and the significant wave height is reduced after the wind field optimization, which is more consistent with the observed data. The model accuracy is improved after optimization; Typhoon Fung-Wong, which crossed Taiwan, showed the most significant reduction in wind speed. Significant wave height is positively correlated with wind speed. The wave height distribution shows a gradually decreasing trend from the cyclone center to the coast, and the significant wave heights of the typhoon moving direction show pronounced asymmetry. Affected by the land topography, the distribution of significant wave height generally shows a downward trend, and the area of height water level area decreases.
Heterogeneous Ensemble Feature Selection for Network Intrusion Detection System
Authors: Damtew Yeshalem Gezahegn , Chen Hongmei , Yuan Zhong 
Published: February 2023

AbstractIntrusion detection systems get more attention to secure the computers and network systems. Researchers propose different network intrusion detection systems using machine learning techniques. However, the massive amount of data that contain irrelevant and redundant features is still challenging the intrusion detection systems. The redundancy and irrelevance of features may slow the processing time and decrease prediction performance. This paper proposes a Heterogeneous Ensemble Feature Selection (HEFS) method to select the relevant features while achieving better attack detection performance. The proposed method fuses the output feature subsets of five filter feature selection methods, using a union combination method, to obtain an ensemble features subset. HEFS method uses merit-based evaluation to avoid the internal redundancy of the obtained ensemble features subset and acquire the final optimal features. We evaluate the HEFS method with random forest, J48, random tree, and REP tree. In a multi-class NSL-KDD dataset, the experimental results show that the proposed method achieves better prediction performance than the specific feature selection methods and other frameworks.