bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sorption of alkylphenols and estrogens on microplastics in marine conditions
Authors: Phuong Ngoc Nam , Zalouk-Vergnoux Aurore , Duong Thi Thuy , Le Thi Phuong Quynh , Poirier Laurence 
Published: April 2023

Abstract
In marine ecosystems, living organisms are continuously exposed to a cocktail of anthropogenic contaminants, such as microplastics (MPs) and endocrine disrupting compounds (EDCs). Being able to adsorb organic compounds, MPs would act as an additional contamination vector for aquatic organisms. To support this hypothesis, the sorption of six EDCs on MPs, including 4-t-butylphenol, 4-t-octylphenol, 4-n-octylphenol, 4-n-nonylphenol, 17β-estradiol and its synthetic analog 17α-ethinylestradiol, has been investigated. These compounds belong to two contaminant families, alkylphenols and estrogens, included in the EU priority and watch lists of the Water Framework Directive. Sorption kinetics were studied onto polyethylene and polypropylene MPs under seawater conditions. MPs at a concentration of 0.400 mg mL−1 were added to a mix of the six EDCs, each at the individual concentration of 100 ng mL−1. The concentrations of contaminants were chosen to be close to environmental ones and comparable with those found in literature. The results demonstrated that the hydrophobicity of the compounds and the MP type are the two factors influencing the sorption capacity. The distribution coefficient (K
d) of each compound was determined and compared to others found in the literature. A high affinity was demonstrated between 4-n-NP and PE, with a sorption reaching up to 2,200 ng mg−1.
Conception of Human Being in Analytical Idealism: How Human and Cosmos are Interlinked Through Consciousness
Authors: Popovič Juraj 
Published: April 2023

Abstract
The relationship between human and cosmos is still quite a mystery. The ancient intuition about interconnectedness of human and cosmos was replaced by a worldview in which human is part of nature primarily through the continuity of the body with the outer nature. The mind is seen as a unique phenomenon mysteriously emerging from matter. To this mystery responds philosopher Bernardo Kastrup by proposing an ontology that turns the mind-matter relationship on its head: the matter is part of the mind, and not vice versa. This article briefly examines the historical evolution of understanding of the relationship between human and cosmos, introduces the ontology called analytical idealism by B. Kastrup and discusses how idealistic ontology can help us understand our relationship with the cosmos on a deeper level.
Computational investigation of Arbutus serratifolia Salisb molecules as new potential SARS-CoV-2 inhibitors
Authors: Belattar Nadjah , Mekkiou Ratiba , Krid Adel , Djekoun Abdelhamid 
Published: April 2023

Abstract
The outbreak of the current pandemic and the evolution of virus resistance against standard drugs led to the emergency of new and potent antiviral agents. Owing to its crucial role in viral replication, the protease enzyme is taken into survey to be a promising target for antiviral drug therapy using computational methods. In order to bring this important class of natural products in the limelight of research for prospective application as chemotherapeutic agents, the anti-SARS-CoV-2 activity of some bioactive molecules obtained from Arbutus serratifolia Salisb which is an Algerian medicinal plant, was investigated using in-silico methods. The molecular docking was performed by AutoDock Vina and UCSF Chimera, as well as ADMET and drug-likeness properties of these molecules were calculated using preADMET web-based application and the Swiss ADME server respectively. The phytochemicals (from Pr(1) to Pr(12)) were tested for their pharmacokinetic properties and docked into the main protease binding site on (PDB ID: 6Y84) in order to find a promising antiviral ligand. All tested molecules induced binding affinities into the binding pocket of (PDB ID: 6Y84) with energy scores ranging from moderate to better (from −6.4 to −8.00 kcal/mol). It is worthy to note that both Pr(2): (1S,5R,6S,8S,9S)-6,8-Dihydroxy-8-methyl-1,5,6,7,8,9-hexahydrocyclopenta [c] pyran-1-yl-β-D-glucopyranoside and Pr(7): ((1S,5S,6S,9S)-1-(β-D-Glucopyranosyloxy)-14-oxo-1,5,6,9-tetrahydro-1H-2,15-dioxacyclopenta [cd] inden-8-yl) methyl acetate, were found to be the best inhibitors with binding affinities (−7.7 kcal/mol and −8.0 kcal/mol), respectively, by virtue of the fact that all these tested molecules exhibited good binding affinities compared with those of Ritonavir and Nirmatrelvir (−1.73 and −1.93 kcal/mol), respectively, which are used as standard antiviral drugs to prevent viral growth. The amino acids: His-163; Glu-166; Arg-188; Thr-190 and Gln-192 represent the key residues of the interaction of SARS-CoV-2 main protease with Pr(7). Furthermore, the results of pharmacodynamic and pharmacokinetic investigations revealed that Pr(6), Pr(8) and Pr(9) uphold the drug-likeness criteria and more particularly, these substances can be absorbed by the human intestine. In addition, all these molecules were shown to be neither hepatotoxic nor significantly noxious to human organism. These natural products are therefore promising inhibitor candidates of viral main protease. However, further in-vitro, in-vivo and even clinical assays are required to probe their functional mechanisms and then to assess their antiviral potency against COVID-19.
Application of Plantain leaves as a bio-adsorbent for biosorption of U(VI) ions from wastewater
Authors: Taheri Mohammad , Khajenoori Maryam , Shiri-Yekta Zahra , Zahakifar Fazel 
Published: April 2023

Abstract
Uranium biosorption was investigated using the bio-adsorbent of Plantain leaves. First, the bio-adsorbent structure was characterized using BET, SEM, and FTIR. The effective parameters pH, initial uranium concentration, bio-adsorbent dose, and the temperature were investigated using a central composite design (CCD). Experimental data were analyzed using Design Expert 12.0.3.0 software. According to the obtained results, the pH value of 4, initial metal ion concentration of 10 mg L−1, the bio-adsorbent dose of 0.297 g, and the temperature of 25 °C were proven for maximum biosorption efficiency of U(VI) ions from aqueous solutions. The contact time was investigated to understand the type of kinetics of the reaction. The maximum biosorption efficiency was 90 min. The optimal biosorption efficiency was 92.69%. The Freundlich isotherm and pseudo-second-order models were the best isotherms and kinetic models fitted with the results of the studied bio-adsorbent, respectively.
Biosynthesis of Ag/bentonite, ZnO/bentonite, and Ag/ZnO/bentonite nanocomposites by aqueous leaf extract of Hagenia abyssinica for antibacterial activities
Authors: Zewudie Adisu Girma , Zereffa Enyew Amare , Segne Teshome Abdo , Murthy H. C. Ananda , Ravikumar C. R. , Muniswamy Dhanalakshmi , Binagdie Bayissa Bekele 
Published: April 2023

Abstract
We report the synthesis of Ag/bentonite, ZnO/bentonite and Ag/ZnO/bentonite nanocomposites (NCs) using Hagenia abyssinica plant extract and their antibacterial study. The synthesized NCs were characterized by using many advanced techniques. The X-ray diffraction and high resolution transmission electron microscopy analysis confirmed the formation of composites with different phases. The average crystallite size (D) values of pure Ag nanoparticles (NPs), ZnO NPs, and activated bentonite (Na-AB) were found to be 8.14, 18.1, and 37.6 nm, respectively. The Ag/bentonite NCs, ZnO/bentonite NCs, and Ag/ZnO/bentonite NCs exhibited the D values of 7.4, 9.4, and 9.4 nm, respectively. The Fourier transform infrared spectral analysis revealed the presence of hydroxyl, carbonyl, and other functional groups on the surface of the synthesized NCs. The transmission electron microscopic analysis revealed the formation of Ag and ZnO NPs with hexagonal, rod-shaped, and spherical structures. HRTEM also revealed the presence of (102) plane of ZnO and (220) plane of Ag in Ag/ZnO/bentonite NCs. The antibacterial activities of the composites suspension were evaluated against Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923 by the disc diffusion and broth dilution methods. The ternary NC and Ag/ZnO/bentonite exhibited better zone of inhibition of 14.3 ± 0.3 and 17.3 ± 0.2 mm at 10 mg·mL−1 toward E. coli and S. aureus bacterial strains. The minimum inhibitory concentration and minimum bactericidal concentration values of Ag/ZnO/bentonite NCs were found to be 156.25 and 312.5 µg·mL−1 for E. coli. The investigation results revealed that the low temperature bio-synthesized Ag/ZnO/bentonite is a promising bactericide over the binary composites.
Impact resistance capacity and degradation law of epoxy-coated steel strand under the impact load
Authors: Li Hongming , Feng Bo , Xu Yan , Zhong Jitao 
Published: April 2023

Abstract
As the main load-bearing component of the bridge structure, the cable is damaged by the impact from time to time, so it is very important to clarify its impact resistance capacity. Based on the method of the drop-weight test, this article mainly studies the degradation law of the mechanical properties of epoxy-coated steel strand (ECSS) under the impact load. Through the impact test of ECSS under different working conditions, the influence law of prestress, impact energy, initial defects and other factors on the impact resistance of the steel strand was revealed. Then, the difference of the impact resistance of ECSS and ordinary steel strand (OSS) was verified under the same impact conditions. Finally, the failure mechanism and the residual-bearing capacity of ECSS were analyzed through the secondary impact test. The results show that the initial prestress is helpful to improve its impact resistance when it is less than 0.11

f

u

{f}_{{\rm{u}}}

, and exceeding this value will accelerate its failure process. The effect of impact height on the strain at the impact point of ECSS is significantly greater than that near the anchor end. ECSS has better energy absorption characteristics than OSS. The impact resistance of ECSS with initial defects is very sensitive to the impact energy. The influence on outer strand in the secondary impact is significantly higher than the central strand, and its residual tensile capacity still has 0.85

f

u

{f}_{{\rm{u}}}

.
Time-of-Day Effects of Exercise on Cardiorespiratory Responses and Endurance Performance—A Systematic Review and Meta-Analysis
Authors: Kang Jie , Ratamess Nicholas A. , Faigenbaum Avery D. , Bush Jill A. , Finnerty Caitlyn , DiFiore Michael , Garcia Andy , Beller Noah 
Published: April 2023

Abstract
Kang, J, Ratamess, NA, Faigenbaum, AD, Bush, JA, Finnerty, C, DiFiore, M, Garcia, A, and Beller, N. Time-of-day effects of exercise on cardiorespiratory responses and endurance performance—A systematic review and meta-analysis. J Strength Cond Res 37(10): 2080–2090, 2023—The time-of-day effect of exercise on human function remains largely equivocal. Hence, this study aimed to further analyze the existing evidence concerning diurnal variations in cardiorespiratory responses and endurance performance using a meta-analytic approach. Literature search was conducted through databases, including PubMed, CINAHL, and Google Scholar. Article selection was made based on inclusion criteria concerning subjects' characteristics, exercise protocols, times of testing, and targeted dependent variables. Results on oxygen uptake (V̇o
2), heart rate (HR), respiratory exchange ratio, and endurance performance in the morning (AM) and late afternoon or evening (PM) were extracted from the chosen studies. Meta-analysis was conducted with the random-effects model. Thirty-one original research studies that met the inclusion criteria were selected. Meta-analysis revealed higher resting V̇o
2 (Hedges' g = −0.574; p = 0.040) and resting HR (Hedges' g = −1.058; p = 0.002) in PM than in AM. During exercise, although V̇o
2 remained indifferent between AM and PM, HR was higher in PM at submaximal (Hedges' g = −0.199; p = 0.046) and maximal (Hedges' g = −0.298; p = 0.001) levels. Endurance performance as measured by time-to-exhaustion or the total work accomplished was higher in PM than in AM (Hedges' g = −0.654; p = 0.001). Diurnal variations in V̇o
2 appear less detectable during aerobic exercise. The finding that exercising HR and endurance performance were greater in PM than in AM emphasizes the need to consider the effect of circadian rhythm when evaluating athletic performance or using HR as a criterion to assess fitness or monitor training.
Impeachment of Regional Heads Resulted in Direct Election in the Perspective of Constitutional Law
Authors: Fakihudin Rifki 
Published: April 2023

This article examines the DPRD authority over the impeachment of regional heads resulting from direct elections. Impeachment is a proposal for dismissal by DPRD against regional heads. The impeachment mechanism emerged after the amendment of the UUD 1945 along with democratic elections. The impeachment process carried out by the DPRD is based on Law Number 9 of 2015 and Government Regulation Number 12 of 2018. This study uses qualitative legal research and a normative juridical approach that is associated with a developing case. The data sources used in this study are primary and secondary legal materials, with analysis using deductive qualitative techniques and aiming to collect information as study material. The authority of the DPRD as a regional institution has a supervisory function over the policies taken by the government, namely the regional head. Through the impeachment mechanism, regional heads can be dismissed if they commit a violation. This study provides an explanation of the ideal mechanism for impeachment of regional heads in the perspective of constitutional law.
Effectiveness of BNT162b2 COVID-19 Vaccination in Children and Adolescents
Authors: Klein Nicola P. , Demarco Maria , Fleming-Dutra Katherine E. , Stockwell Melissa S. , Kharbanda Anupam B. , Gaglani Manjusha , Rao Suchitra , Lewis Ned , Irving Stephanie A. , Hartmann Emily , Natarajan Karthik , Dalton Alexandra F. , Zerbo Ousseny , DeSilva Malini B. , Konatham Deepika , Stenehjem Edward , Rowley Elizabeth A. K. , Ong Toan C. , Grannis Shaun J. , Sloan-Aagard Chantel , Han Jungmi , Verani Jennifer R , Raiyani Chandni , Dascomb Kristin , Reese Sarah E. , Barron Michelle A. , Fadel William F. , Naleway Allison L. , Nanez Juan , Dickerson Monica , Goddard Kristin , Murthy Kempapura , Grisel Nancy , Weber Zacharay A. , Dixon Brian E. , Patel Palak , Fireman Bruce , Arndorfer Julie , Valvi Nimish R. , Griggs Eric P. , Hallowell Carly , Embi Peter J. , Ball Sarah W. , Thompson Mark G. , Tenforde Mark W. , Link-Gelles Ruth 
Published: April 2023

OBJECTIVES
We assessed BNT162b2 vaccine effectiveness (VE) against mild to moderate and severe coronavirus disease 2019 (COVID-19) in children and adolescents through the Omicron BA.4/BA.5 period.

METHODS
Using VISION Network records from April 2021 to September 2022, we conducted a test-negative, case-control study assessing VE against COVID-19-associated emergency department/urgent care (ED/UC) encounters and hospitalizations using logistic regression, conditioned on month and site, adjusted for covariates.

RESULTS
We compared 9800 ED/UC cases with 70 232 controls, and 305 hospitalized cases with 2612 controls. During Delta, 2-dose VE against ED/UC encounters at 12 to 15 years was initially 93% (95% confidence interval 89 to 95), waning to 77% (69% to 84%) after ≥150 days. At ages 16 to 17, VE was initially 93% (86% to 97%), waning to 72% (63% to 79%) after ≥150 days. During Omicron, VE at ages 12 to 15 was initially 64% (44% to 77%), waning to 13% (3% to 23%) after ≥150 days; at ages 16 to 17 VE was 31% (10% to 47%) during days 60 to 149, waning to 7% (−8 to 20%) after 150 days. A monovalent booster increased VE to 54% (40% to 65%) at ages 12 to 15 and 46% (30% to 58%) at ages 16 to 17. At ages 5 to 11, 2-dose VE was 49% (33% to 61%) initially and 41% (29% to 51%) after 150 days. During Delta, VE against hospitalizations at ages 12 to 17 was high (&gt;97%), and at ages 16 to 17 remained 98% (73% to 100%) beyond 150 days; during Omicron, hospitalizations were too infrequent to precisely estimate VE.

CONCLUSIONS
BNT162b2 protected children and adolescents against mild to moderate and severe COVID-19. VE was lower during Omicron predominance including BA.4/BA.5, waned after dose 2 but increased after a monovalent booster. Children and adolescents should receive all recommended COVID-19 vaccinations.
PEDAGOGIA HISTÓRICO-CRÍTICA NAS PRODUÇÕES CIENTÍFICAS DE PERIÓDICOS EDUCACIONAIS CEARENSES
Authors: Neves Vanusa Nascimento Sabino , Sales José Albio Moreira 
Published: April 2023

A pesquisa trata da pedagogia histórico-crítica, idealizada por Saviani a partir da década de 1980, na intenção de incorporar os avanços e superar os limites verificados no âmbito das pedagogias antecedentes. Objetivou-se analisar a produção difundida pelas revistas Educação & Formação, Ensino em Perspectivas e Práticas Educativas, Memórias e Oralidades, vinculadas ao Programa de Pós- -Graduação da Universidade Estadual do Ceará, para identificar as categorias temáticas pertinentes ao uso e às apropriações das concepções de Saviani sobre a pedagogia histórico-crítica. Realizou-se um estudo qualitativo, do tipo estado da arte, firmado na análise do conteúdo. A partir da leitura integral dos 13 produtos selecionados, emergiram quatro categorias temáticas: 1) relação escola e trabalho; 2) trabalho docente; 3) formação docente; e 4) políticas públicas educacionais. Concluiu-se que a interlocução com as concepções de Saviani fundamenta o debate de uma multiplicidade de temas no campo educacional que estimulam uma prática docente contra-hegemônica.
POSSÍVEIS CONTRIBUIÇÕES DA REFORMA EDUCACIONAL ESCOCESA PARA A IMPLANTAÇÃO DA BNCC NO BRASIL
Authors: Pereira Ana Lúcia 
Published: April 2023

O presente artigo tem como objetivo apresentar resultados de um projeto de pesquisa que objetivou construir conhecimentos sobre os desafios da formação de professores em um contexto de reforma educacional, a partir do paradigma de reforma educacional bem-sucedida realizada pela Escócia, país constituinte do Reino Unido e de alto desenvolvimento econômico, que a partir do início deste século iniciou o processo que culminou na implantação em todo o país do chamado Curriculum for Excellence (CfE). A pesquisa é de natureza qualitativa e a investigação consistiu de análise aprofundada dos documentos que embasaram as propostas escocesa e brasileira. Nesse sentido, o presente artigo tem como objetivo identificar paralelos entre os processos de reforma curricular escocês e brasileiro, e através destes paralelos, contribuir para o aprofundamento das discussões em curso no Brasil acerca da BNCC e da reforma do Ensino Médio. Como resultados identificamos seis pontos onde traçamos alguns paralelos que podem contribuir com os debates em eventuais necessidades de correções de rumo no processo de reformas no Brasil. As reflexões aqui apresentadas também podem contribuir para a elaboração de propostas para enfrentar os desafios inerentes à formação inicial e continuada de professores no ambiente de reforma que ainda vamos enfrentar futuramente com a implantação da BNCC.
CURRÍCULO COMO POSSIBILIDADE DE RESISTÊNCIA, DE CRIAÇÃO, DE SOLIDARIEDADES E AFIRMAÇÃO DE UMA VIDA BONITA
Authors: Ferraço Carlos Eduardo , Piontkovsky Danielle , Gomes Marco Antonio Oliva , Gomes Maria Regina Lopes 
Published: April 2023

Trata-se de Dossiê que tem como tema articulador “O currículo como possibilidade de resistência, de criação, de solidariedades e afirmação de uma vida bonita”, de modo a se constituir como uma forma de luta por uma vida mais bonita na educação. Nesse sentido, privilegiou os saberes-fazeres que são tecidos com os cotidianos das escolas, em especial as públicas que criam currículos em redes, entendendo a vida como multiplicidade, encharcada de políticas inventivas. Tendo em vista os tempos sombrios que estamos vivendo, tempos marcados por discursos que buscam anular a diferença e produzir desesperança, apostamos em uma composição de textos assumindo o campo do currículo campo fértil de possibilidades, de resistências, de criações, de solidariedades e de afirmação de uma vida bonita.
Phytodiversity Estimation of High-altitude Pastureland Above Yonphula, Kanglung Gewog, Trashigang Dzongkhag
Authors: Tshering Nythri , Wangchuck Karma 
Published: April 2023

High altitude pasturelands (Tsamdro) are important grazing grounds of livestock in Bhutan. Pasturelands are degrading due to overgrazing and shrub encroachment along with climate change. The lack of floristic knowledge of such pastureland would mean permanent loss of phytodiversity if not studied timely. This floristic study was conducted for two seasons using quadrat method of vegetation analyses. Phytodiversity was determined using different biodiversity indices. A total of 83 species in 60 genera belonging to 35 families were recorded from the pastureland including two endemic species, Halenia elliptica D. Don and Viola bhutanica H. Hara. Asteraceae, Rosaceae and Gentianaceae are species rich families. Species indicated a high richness with 2.17, dominance index was 0.92 for species like Elsholtzia strobilifera (Benth) Benth, Swertia spp., Fragaria nubicola (Lindl. ex. Hook.f.) Lacaita, Potentilla sp., Trifolium repens L., Euphorbia griffithii Hook. f., and Plantago erosa Wall. The diversity value was 2.97, indicating low diversity with even distribution (0.91). Similarity index of 0.70 indicated fairly similar floristic composition in autumn and spring seasons. This study provides basic information on floristic composition and phytodiversity of pastureland, which can be incorporated for pastureland management and conservation.
An observational study to compare the effect of intravenous dexmedetomidine versus intravenous magnesium sulphate pretreatment on characteristics of spinal anaesthesia
Authors: Pandey Vandana , Gajendra Akash , Vatsalya Tripti , Gupta Vikas , Mehrotra Shikha 
Published: April 2023

The study was conducted to assess & compare the effect of pretreatment with intravenous Dexmedetomidine and Magnesium sulphate on characteristics of SAB with hyperbaric bupivacaine. 80 ASA grade I and II patients (age: 18-60 years) scheduled for infraumblical surgery under spinal anesthesia were included & randomly divided into group-D (dexmedetomidine 1μ gm/kg) and group-M (magnesium sulfate 50 mg/kg). patients were given prefixed doses of either intravenous dexmedetomidine or Magnesium sulfate 15 mins before SAB. Incidence of hypotension, highest level & duration of sensory & motor blockage, duration of analgesia, vasopressor requirement and incidence of sedation, nausea & vomiting were compared. highest upper level of sensory block after SAB was higher in group-D (p value &#60; 0.001) than group-M. onset of sensory & motor block was earlier & duration of sensory and motor block, time of rescue analgesia was longer in group-D (p value &#60; 0.001). Depth of sedation was higher in group-D though oxygen saturation and respiratory rate was comparable in both groups. Postoperative VAS score (p value &#60; 0.001) was lower in dexmedetomidine group.Study suggests that Intravenous dexmedetomidine at a dose of 1μg/kg is a better adjuvant to 0.5% hyperbaric bupivacaine than MgSo at a dose of 50 mg/kg in infra-umbilical surgeries, with complications of hypotension and bradycardia occurring at acceptable incidences.