bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eurasian consumers' food safety beliefs and trust issues in the age of COVID‐19: evidence from an online survey in 15 countries
Authors: Tomasevic Igor , Hambardzumyan Garegin , Marmaryan Gayane , Nikolic Aleksandra , Mujcinovic Alen , Sun Weizheng , Liu Xiao‐Chen , Bursać Kovačević Danijela , Markovinović Anica Bebek , Terjung Nino , Heinz Volker , Papageorgiou Maria , Skendi Adriana , Goel Gunjan , Raghav Mamta , Dalle Zotte Antonella , Nakov Dimitar , Velkoska Valentina , Sołowiej Bartosz G. , Semenova Anastasia A. , Kuznetsova Oksana A. , Krocko Miroslav , Duckova Viera , Lorenzo Jose M. , Echegaray Noemi , Oz Emel , Oz Fatih , Djekic Ilija 
Published: July 2023

AbstractBACKGROUNDThis investigation provides an important insight into Eurasian consumers' food safety beliefs and trust issues influenced by the COVID‐19 pandemic. An online survey was conducted in 15 European and Asian countries involving more than 4000 consumers.RESULTSIt has confirmed that different socioeconomic characteristics, cultural aspects and education levels shape food safety perceptions within Eurasian countries. The COVID‐19 pandemic influenced their beliefs and trust in food safety, which is relatively low on average. However, it is significantly higher for European consumers (especially European Union ones) compared to their Asian counterparts. Both Asian and European respondents agreed that food fraud and climate changes represent a food safety issue. However, European consumers were less concerned regarding the food safety of genetically modified foods and meat and dairy analogs/hybrids. Asian consumers were, to a greater extent, worried about the risk of getting COVID‐19 from food, restaurants, food retail establishments and home food deliveries.CONCLUSIONEurasian consumers have put their greatest extent of trust, when food safety assurance is concerned, into food scientists and food producers holding a food safety certificate. Broadly, they are uncertain to what extent their federal governments and food inspectors are competent, able and efficient in ensuring food safety. Higher education of Eurasian consumers was followed by increased food safety confidence in all parts of the food chain. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Reduced skin permeation and penetration of clobetasol propionate when Dermovate cream is applied at short time intervals with emollients
Authors: Beebeejaun M. T. , Brown M. B. , Hutter V. , Kravitz L. , McAuley W. J. 
Published: July 2023

AbstractBackgroundDermovate cream containing 0.05% clobetasol propionate is a very potent topical corticosteroid (TCS) used in the treatment of severe inflammatory dermatoses. Regular emollient therapy should continue alongside clobetasol propionate treatment, however, the impact on drug delivery to the skin when both products are applied at similar times is unknown.ObjectivesTo assess whether application of emollients at similar times to Dermovate cream alter the delivery of clobetasol propionate to the skin.MethodsThis study was conducted using ex vivo human skin mounted in Franz cells. Dermovate cream was applied before or after three different emollients, Hydromol Intensive cream, Doublebase gel, and Diprobase ointment at 5‐ or 30‐min intervals. Drug delivery to the skin was assessed up to 24 h using high‐performance liquid chromatography.ResultsSignificantly reduced clobetasol propionate delivery to the skin was observed when Dermovate cream was applied either before or after the three different emollients, compared to the application of Dermovate cream alone. The data suggest in situ formation of a mixed Dermovate cream and emollient layer which reduces clobetasol propionate delivery relative to the original product. Applying Dermovate cream after any emollient generally resulted in larger reductions in drug delivery to the skin, compared to when the steroid was applied first. This was attributed to the emollients forming an additional barrier to drug delivery at the skin‐formulation interface.ConclusionsThese findings indicate that applying Dermovate cream at similar times as emollients can significantly reduce drug delivery to the skin and that separating the application of the two products by intervals of up to 30 min is not sufficient to mitigate this effect.
Different doses of vitamin D supplementation to nonsurgical treatment for vitamin‐D‐insufficient patients with diabetic periodontitis and the effect on gingival BMP‐2 levels
Authors: Lei Fei , Ni Jing , Hu Jin‐Long , Guo Dan‐Ni , Fan Jing 
Published: July 2023

AbstractEpidemiological data show people with diabetes mellitus (DM) have three‐fold increase in risk of periodontitis. A vitamin D insufficiency can affect the progression of DM and periodontitis. This study evaluated the effects of different‐dose vitamin D supplementation to nonsurgical periodontal therapy for vitamin‐D‐insufficient diabetic patients coexisting with periodontitis and changes of gingival bone morphogenetic protein‐2 (BMP‐2) levels. The study included 30 vitamin‐D‐insufficient patients receiving nonsurgical treatment followed by administration of 25,000 international units (IU) vitamin D3 per week (the low‐VD group) and 30 patients receiving 50,000 UI vitamin D per week (the high‐VD group). The decreases of probing pocket depth, clinical attachment loss, bleeding index, and periodontal plaque index values of patients after the six‐month supplementation of 50,000 UI vitamin D3 per week to nonsurgical treatment were more significant than those after the six‐month supplementation of 25,000 UI vitamin D3 per week to nonsurgical treatment. It was found that 50,000 IU per week vitamin D supplementation for 6 months could lead to a better glycemic control for vitamin‐D‐insufficient diabetic patients coexisting with periodontitis after nonsurgical periodontal therapy. Increased levels of serum 25(OH) vitamin D3 and gingival BMP‐2 were found in both low‐ and high‐dose VD groups, and the high‐dose VD group exhibited higher levels than the low‐dose VD group. Vitamin D supplementation in large doses for 6 months tended to improve the treatment of periodontitis and increase gingival BMP‐2 levels in diabetic patients coexisting with periodontitis who were vitamin D deficient.
Forecasting Rural and Urban Otolaryngologists, Radiation Oncologists, and Oropharyngeal Carcinoma
Authors: Falk Grace E. , Okut Hayrettin , Lightner Joseph S. , Farrokhian Nathan , LaCrete Frantzlee , Chiu Alexander , Shnayder Yelizaveta , Bond Justin , Sykes Kevin J. 
Published: July 2023

ObjectiveTo forecast oropharyngeal carcinoma (OPC) incidence with otolaryngologist and radiation oncologist numbers per population by rural and urban counties through 2030.MethodsIncident OPC cases were abstracted from the Surveillance, Epidemiology, and End Results 19 database, and otolaryngologists and radiation oncologists from the Area Health Resources File by county from 2000 to 2018. Variables were analyzed by metropolitan counties with over 1,000,000 people (large metros), rural counties adjacent to a metro (rural adjacent), and rural counties not adjacent to a metro (rural not adjacent). Data were forecasted via an unobserved components model with regression slope comparisons.ResultsPer 100,000 population, forecasted OPC incidence increased from 2000 to 2030 (large metro: 3.6 to 10.6 cases; rural adjacent: 4.2 to 11.9; rural not adjacent: 4.3 to 10.1). Otolaryngologists remained stable for large metros (2.9 to 2.9) but declined in rural adjacent (0.7 to 0.2) and rural not adjacent (0.8 to 0.7). Radiation oncologists increased from 1.0 to 1.3 in large metros, while rural adjacent remained similar (0.2 to 0.2) and rural not adjacent increased (0.2 to 0.6). Compared to large metros, regression slope comparisons indicated similar forecasted OPC incidence for rural not adjacent (p = 0.58), but greater for rural adjacent (p < 0.001, r = 0.96). Otolaryngologists declined for rural regions (p < 0.001 and p < 0.001, r = −0.56, and r = −0.58 for rural adjacent and not adjacent, respectively). Radiation oncologists declined in rural adjacent (p < 0.001, r = −0.61), while increasing at a lesser rate for rural not adjacent (p = 0.002, r = 0.96).ConclusionsRural OPC incidence disparities will grow while the relevant, rural health care workforce declines.Level of EvidenceNA Laryngoscope, 134:136–142, 2024
A New Strong‐Acid Free Route to Produce Xanthan Gum‐PANI Composite Scaffold Supporting Bioelectricity
Authors: Pescosolido Francesca , Montaina Luca , Carcione Rocco , Politi Sara , Matassa Roberto , Carotenuto Felicia , Nottola Stefania Annarita , Nardo Paolo Di , Tamburri Emanuela 
Published: July 2023

AbstractConductive hybrid xanthan gum (XG)–polyaniline (PANI) biocomposites forming 3D structures able to mimic electrical biological functions are synthesized by a strong‐acid free medium. In situ aniline oxidative chemical polymerizations are performed in XG water dispersions to produce stable XG–PANI pseudoplastic fluids. XG–PANI composites with 3D architectures are obtained by subsequent freeze‐drying processes. The morphological investigation highlights the formation of porous structures; UV–vis and Raman spectroscopy characterizations assess the chemical structure of the produced composites. I–V measurements evidence electrical conductivity of the samples, while electrochemical analyses point out their capability to respond to electric stimuli with electron and ion exchanges in physiological‐like environment. Trial tests on prostate cancer cells evaluate biocompatibility of the XG–PANI composite. Obtained results demonstrate that a strong acid‐free route produces an electrically conductive and electrochemically active XG–PANI polymer composite. The investigation of charge transport and transfer, as well as of biocompatibility properties of composite materials produced in aqueous environments, brings new perspective for exploitation of such materials in biomedical applications. In particular, the developed strategy can be used to realize biomaterials working as scaffolds that require electrical stimulations for inducing cell growth and communication or for biosignals monitoring and analysis.
Seeking sanctuary: Housing undocumented immigrants
Authors: Christopher Derek 
Published: July 2023

AbstractThis paper studies housing market outcomes of undocumented immigrants in the U.S. and explores the mechanisms behind the differential prices that immigrants pay for shelter. I show that undocumented renters pay a premium for housing relative to observably similar, documented, immigrant renters occupying similar housing. Building on theory and suggestive evidence that the premium is the result of search frictions driven by fear of deportation, I employ a triple‐differences strategy to evaluate the impacts of sanctuary city policies on housing market outcomes of undocumented immigrants. I find that sanctuary city policies, which limit immigration enforcement, reduce housing costs of undocumented renters, suggesting such policies mitigate search frictions for this group.
Was macht Mathematik effektiv?
Authors: Loos Andreas , Sinn Rainer , Ziegler Günter M. 
Published: July 2023

ZusammenfassungMathematik scheint den natürlichen Formalismus zur Beschreibung und Berechnung physikalischer Prozesse und Gesetzmäßigkeiten zu liefern. Umgekehrt haben physikalische Fragestellungen die Entwicklung der Mathematik angeregt und teilweise ihre Richtung bestimmt, und eigentlich gibt es keine scharfe Grenze zwischen Mathematik und Physik. Eine sinnvolle Einteilung bezieht sich eher auf die Motivation als auf die Untersuchungsgegenstände der Mathematik: Forschung wird betrieben, um mathematische Strukturen zu verstehen oder ist durch naturwissenschaftliche oder technisch‐industrielle Anwendungen motiviert.
Do self and interpersonal dysfunction cross‐sectionally mediate the association between adverse childhood experiences and personality pathology?
Authors: Evans Chloe M. , Simms Leonard J. 
Published: July 2023

AbstractTwo primary limitations of research on the association between adverse childhood experiences (ACEs) and personality disorder (PD) are (1) failure to consider mechanisms of association and (2) inconsistent results due, in part, to inconsistent approaches to quantifying ACE exposure. The current study will address these limitations by examining the cross‐sectional mediating role of self‐ and interpersonal dysfunction on the association between ACE and three PDs (antisocial, schizotypal, and borderline) using three quantifications of ACE exposure (cumulative, individual, and unique risk). Participants were 149 current or recent psychiatric patients, and data analyses were performed through estimation of a series of cross‐sectional mediation models. Taken together, results suggest that (1) the association between ACE and PD is moderate, (2) self‐ and interpersonal dysfunction cross‐sectionally mediate this association, (3) after accounting for variance shared among ACEs, associations between specific ACE subtypes and PD were negligible, (4) much of the association between ACE and PD is accounted for by general processes impacted by all forms of ACE and implicated in all forms of PD, and (5) emotional neglect may uniquely contribute to self‐ and interpersonal dysfunction and thereby, PD risk.
Phosphorus, cobalt‐phosphorus, and nickel‐phosphorus clusters: Growth behavior, electronic, and magnetic properties
Authors: Roumili M. A. , Mahtout S. , Baddari K. , Lasmi M. , Rabilloud F. 
Published: July 2023

AbstractThe equilibrium geometries, and electronic and magnetic properties of phosphorus, cobalt‐phosphorus, and nickel‐phosphorus (Pn+1, CoPn, and NiPn, n = 1–24) clusters have been investigated by using first principle calculations. The doping with cobalt or nickel atom favors the endohedral structures in which the metal atom is encapsulated inside the phosphorus framework, while geometrical structures are metal‐dependent. The growth pattern behaviors and stabilities are examined from the binding energies, the second‐order energy differences, and the HOMO–LUMO gaps. The doping with Co or Ni atom contributes to strengthening the stability of the phosphorus frame with a marked improvement in the case of Ni atom. The total spin magnetic moment is enhanced with doping with Co atom. In contrast, the magnetic moment is quenched in the case of NiPn. Vertical electron affinities and ionization potentials are also reported and discussed.
Computational Investigation of Isoxazole‐Based Molecules as Potential Drug‐Resistant Anti‐Tuberculosis H37Rv.
Authors: Moukhliss Youness , Koubi Yassine , Alaqarbeh Marwa , Maghat Hamid , Sbai Abdelouahid , Bouachrine Mohammed , Lakhlifi Tahar 
Published: July 2023

AbstractInvestigation of new active therapeutic drugs against the emerging drug‐resistant Mycobacterium tuberculosis is a current medical and health challenge. Based on previously reported isoxazole‐based molecules that have a potent effect against Mycobacterium tuberculosis, computational methods were used in the current study to investigate the effect of isoxazole‐based molecules as a potential active drug‐resistant drug Mycobacterium tuberculosis H37Rv. Molecular models of isoxazole‐based molecules were established by 3D‐QSAR study, and different results were interpreted to propose 6 candidate agents more active than the previously reported compounds in the literature. Also, the candidate structures are more active than the therapeutic drug agent Isoniazid (NIH) against Mycobacterium Tuberculosis. Evaluation of the synthetic accessibility coefficient and the Lipinski properties of newly designed agent candidates indicate that these agents meet the criteria of a drug according to the Lipinski and Veber rules because they can be synthesized. In‐silico evaluation of ADMETox properties shows satisfactory results for most newly designed agent candidates. According to molecular docking, the drug candidates have a high score with a stable docked pose in the receptor (PDB code: 5v3y) compared to Isoniazid (NIH). The DFT and molecular dynamics study confirmed the previous results of 3D‐QSAR and molecular docking models.
Berberine Exhibits Anti‐atherosclerotic Effects in a Mouse Model by Targeting the JAK/STAT Pathway
Authors: Junfeng Sun Mmed. , Xiaojun Zheng Mmed. , Qiang Gao Mmed. , Hussain Lone Nisar 
Published: July 2023

AbstractAtherosclerosis, a serious and commonly diagnosed pathological condition is the main cause of coronary and cerebrovascular disorder which has a high rate of morbidity and mortality globally. In the present study effect of berberine on damage to the aorta wall induced by atherosclerosis in mice model was investigated. The results demonstrated that berberine treatment significantly (P<0.05) reverses the atherosclerosis‐induced increase in the area of the lesions in the mice aortas. Berberine treatment at 0.5, 1.0 and 2.0 mg/kg doses reduced lesion area in the aorta of atherosclerosis mice to 53.5±3.69, 39.4±3.69 and 13.8±2.12 %, respectively. Atherosclerosis‐induced up‐regulation of interleukin (IL)‐1β and IL‐6 production was down‐regulated in mice aortas on treatment with berberine. Treatment with berberine downregulated the atherosclerosis‐induced increase in expression of monocyte chemoattractant protein‐1 (MCP‐1), tumor necrosis factor (TNF)‐α, angiotensin II (AngII), Alveolar type 2 progenitor cells (AT1), and AT2 in mice aorta tissues. Moreover, berberine treatment of atherosclerosis mice led to a marked reduction in the activation of signal transducer and activator of transcription 3 (STAT3), p65, and p38 proteins. In summary, berberine treatment reverses damage associated with atherosclerosis in mice aorta walls by inhibiting the inflammatory response. It targets activation of Janus kinase (JAK)/STAT pathway and downregulated RAAS expression in atherosclerotic mice. Therefore, berberine may be developed as a potential chemotherapeutic agent for atherosclerosis treatment.
Effect of Small Change in Reaction Conditions on the Size of Monoclinic BiVO4 Nanoparticles and their Photocatalytic Abilities
Authors: Ghaware Rachana , Sanadi Prashant , Narale Dattatray , Bhosale Rakhee , Patil Komal , Kim Jin H. , Kolekar Sanjay 
Published: July 2023

AbstractBiVO4 is an effective material and highly used in different applications. Here, we have synthesized BiVO4 using bismuth nitrate pentahydrate and ammonium metavanadate by simple reflux condensation method without addition of any surfactant. To check the effect on the structure and activity of BiVO4 different ratios of bismuth nitrate pentahydrate to ammonium metavanadate e. g. 1 : 1, 1 : 2 and 2 : 1 were used. Obtained BiVO4 nanomaterial was successfully analysed using various analytical techniques such X‐ray diffraction (XRD), Brunauer–Emmett–Teller (BET), Field emission scanning electron microscopy (FE‐SEM) and X‐ray photoelectron spectroscopy (XPS). The nanoparticles were shown spherical morphology, high porosity and monoclinic scheelite (m) crystalline phase. It was observed that BiVO4 nanoparticles prepared using 1 : 1 ratio have very small size as compared to those prepared using other ratios. Further, the photocatalytic activity of the BiVO4 nanoparticles was assessed by photodegradation of crystal violet dye (CV) under visible light irradiation and found that the particles prepared with 1 : 1 ratio were showing high efficiency of degradation. In addition, prepared nanoparticles have shown good antibacterial properties.
Reduction of Amides to Amines Catalyzed by Ca(CH2C6H4NMe2‐o)2(THF)2/HBpin
Authors: Liu Xunqingze , Xie Hongzhen , Luo Yunjie 
Published: July 2023

AbstractReduction of amides to amines is an attractive subject in organic synthesis. Ca(CH2C6H4NMe2‐o)2(THF)2, an easily accessible main‐group complex, on combination with pinacolborane (HBpin) could serve as a highly active catalyst system in the reduction of primary, secondary and tertiary amides into the corresponding amines. This protocol showed good tolerance for functional groups and heteroatoms, and the aimed products could be obtained in a gram‐scale. The active species in this transformation was supposed to be a calcium hydride.
An Ultrasensitive Plasmonic Sensor Based on 2D Ferroelectric Bi2O2Se
Authors: Wang Zheng , Liu Lixuan , Zhai Kun , Nie Anmin , Xiang Jianyong , Mu Congpu , Wen Fusheng , Wang Bochong , Shu Yu , Xue Tianyu , Liu Zhongyuan 
Published: July 2023

AbstractPlasmonic biosensing is a label‐free detection method that is commonly used to measure various biomolecular interactions. However, one of the main challenges in this approach is the ability to detect biomolecules at low concentrations with sufficient sensitivity and detection limits. Here, 2D ferroelectric materials are employed to address the issues with sensitivity in biosensor design. A plasmonic sensor based on Bi2O2Se nanosheets, a ferroelectric 2D material, is presented for the ultrasensitive detection of the protein molecule. Through imaging the surface charge density of Bi2O2Se, a detection limit of 1 fM is achieved for bovine serum albumin (BSA). These findings underscore the potential of ferroelectric 2D materials as critical building blocks for future biosensor and biomaterial architectures.
Abandon the idea of an “optimal economic path” for climate policy
Authors: Koomey Jonathan , Hausker Karl , Schmidt Zachary , Lashof Dan 
Published: July 2023

AbstractMany economic modelers believe that there is an “optimal economic path” for solving the climate problem that exists independent of human choices. This belief rests on the notion that Integrated Assessment Models can determine the path that “maximizes global welfare” and, in turn, this path should drive climate policy. This commentary focuses on an under‐appreciated problem with that belief. We argue that the existence of pervasive increasing returns to scale, network externalities, learning curves, spillovers, and other nonlinear effects puts the idea of a single optimal economic path at odds with our current understanding of the most important forces driving the development of real economic and technological systems. We further argue that this idea is detrimental to rigorous understanding of climate solutions.This article is categorized under:
Assessing Impacts of Climate Change > Scenario Development and Application
Climate Economics > Economics and Climate Change
Climate Economics > Economics of Mitigation
Nonsurgical rhinoplasty
Authors: Hall Suzel S. , Kontis Theda C. 
Published: July 2023

AbstractInterest in liquid, or nonsurgical rhinoplasty, has increased in demand as patients pursue less invasive techniques to achieve their aesthetic goals. Improved filler technology and refinement in injection techniques have made liquid rhinoplasty a reasonable choice for well‐selected patients in both primary and revision rhinoplasty cases. This article reviews nasal anatomy, injection techniques, selected applications, and safety measures pertinent to performing nonsurgical rhinoplasty.