bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual‐Functional Z‐Scheme TiO2@MoS2@NC Multi‐Heterostructures for Photo‐Driving Ultrafast Sodium Ion Storage
Authors: Li Jinhang , Zhang Yuqiang , Mao Yiyang , Zhao Yingying , Kan Dongxiao , Zhu Kai , Chou Shulei , Zhang Xitian , Zhu Chunling , Ren Jing , Chen Yujin 
Published: May 2023

AbstractExploiting dual‐functional photoelectrodes to harvest and store solar energy is a challenging but efficient way for achieving renewable energy utilization. Herein, multi‐heterostructures consisting of N‐doped carbon coated MoS2 nanosheets supported by tubular TiO2 with photoelectric conversion and electronic transfer interfaces are designed. When a photo sodium ion battery (photo‐SIB) is assembled based on the heterostructures, its capacity increases to 399.3 mAh g−1 with a high photo‐conversion efficiency of 0.71 % switching from dark to visible light at 2.0 A g−1. Remarkably, the photo‐SIB can be recharged by light only, with a striking capacity of 231.4 mAh g−1. Experimental and theoretical results suggest that the proposed multi‐heterostructures can enhance charge transfer kinetics, maintain structural stability, and facilitate the separation of photo‐excited carriers. This work presents a new strategy to design dual‐functional photoelectrodes for efficient use of solar energy.
Selective Terminal Functionalization of Linear Alkanes**
Authors: Bruffaerts Jeffrey , Kesten Inbar , Buhnik‐Rosenblau Keren , Cohen Anthony , Edri Nurit , Cormier Morgan , Zhang Yuanfei , Ho Guo‐Ming , Massad Itai , Halfon‐Verner Hila , Kashi Yechezkel , Marek Ilan 
Published: May 2023

AbstractA two‐step sequential strategy involving a biocatalytic dehydrogenation/remote hydrofunctionalization, as a unified and versatile approach to selectively convert linear alkanes into a large array of valuable functionalized aliphatic derivatives is reported. The dehydrogenation is carried out by a mutant strain of a bacteria Rhodococcus and the produced alkenes are subsequently engaged in a remote functionalization through a metal‐catalyzed hydrometalation/migration sequence that subsequently react with a large variety of electrophiles. The judicious implementation of this combined biocatalytic and organometallic approach enabled us to develop a high‐yielding protocol to site‐selectively functionalize unreactive primary C−H bonds.
Walk‐in Together: A pilot study of a walk‐in online family therapy intervention
Authors: Hartley Eliza , Moore Lynda , Knuckey Aaron , von Doussa Henry , Painter Felicity , Story Karen , Barrington Nick , Young Jeff , McIntosh Jennifer 
Published: May 2023

AbstractMany Australians are requiring mental health care, including families, leading to long wait times in order to access support. Walk‐in therapy reduces barriers to mental health support services by providing support at the time that families seek help. This paper presents a proof‐of‐concept study investigating the acceptability and short‐term effectiveness of an online walk‐in family therapy service, Walk‐in Together (WIT). Part 1 of the paper describes the experiences of 44 family members from 22 families who presented to a public family therapy clinic for a virtual walk‐in family therapy session. The session was conducted by a team of three experienced family therapists. Family members' experiences were sought pre‐session, post‐session, and at 6 weeks follow‐up via survey and interview. Part 2 of the paper explores therapist perceptions (n = 7) of the WIT approach, through thematic analysis of semi‐structured interview data. Post‐session feedback showed 85% of family members found WIT to be helpful and 50% were optimistic about their future as a family after their WIT session. Six weeks post‐session it was revealed that WIT supported planning for families in equipping them to move forward with 88% of family members reporting that they knew what to do after the session. All therapists uniformly experienced the model as offering a timely and beneficial service, suitable for diverse presentations and constellations of families. These preliminary results suggest the significant utility of this WIT intervention as a well‐received and helpful service for families, who valued the easy access and rapid therapeutic response afforded by the online, walk‐in delivery model. This proof‐of‐concept paper suggests the potential for further development and growth of WIT, as well as other mental health support services using a walk‐in, telehealth model to meet the rising demand for therapeutic support for families in distress.
Effectiveness of the Coral Tree Family Service family inpatient unit: a longitudinal study exploring change in family functioning
Authors: Plunkett Leah J. , Reece John , Symond Matthew P. , Leung Tania 
Published: May 2023

AbstractChild mental health disorders represent a major burden to public health in Australia due to high prevalence rates, the widespread impact across domains, and the potential for difficulties to persist into adolescence and adulthood. Extensive evidence exists for the use of parent management training and cognitive behavioural therapy to treat difficulties experienced by children; however, a proportion of children do not benefit as expected from these treatments. The use of complementary therapeutic approaches and variations to the mode and intensity of existing intervention is warranted; family inpatient units represent a unique example of this. The aim of this study is to evaluate the effectiveness of a well‐established Australian inpatient unit that admits the whole family, for children aged 12 years and younger referred with mental health, behavioural, or emotional difficulties. This study's longitudinal within‐subject study design utilised routinely collected outcome data from the systemic clinical outcome and routine evaluation, 15 item (SCORE‐15)—a valid and reliable measure of family functioning—from a sample of 980 participants attending the Family Residential Program. This study reported significant improvement in family functioning across all outcome variables between baseline and post‐intervention, with no variables returning to pre‐intervention levels at follow‐up. Clinically significant changes in overall family functioning showed that 37% of participant scores moved from the clinical range at baseline to the nonclinical range post‐intervention. This study represents the first empirical evaluation of the Family Residential Program, and the reported results provide compelling evidence for the program to effect improvement in family functioning for families with long‐standing and severe difficulties. Poor rates of questionnaire completion following intervention frequent the literature base of family inpatient units, with low post‐intervention (56%) and follow‐up (12%) rates evident in this study. This study uniquely contributes to the growing evidence base of family inpatient units using rigorous evaluation methods.
Different cationic functionalized epichlorohydrin modified polyvinyl alcohol based anion exchange membrane
Authors: Jiang Ying , Shen Chunhui , Chen Junjie , Lu Hao , Guo Yichuan , Gao Shanjun 
Published: May 2023

AbstractLow ionic conductivity and poor alkali resistance have long been the problems of the anion exchange membrane (AEM) of alkaline fuel cell. Herein, epichlorohydrin functionalized by three different cations (piperidine cation, imidazole cation and trimethylammonium cation) are respectively used to modify polyvinyl alcohol (PVA) to prepare a series of PVA based AEMs, and the AEMs are cross‐linked by p‐phthalaldehyde. 1H NMR and FT‐IR spectroscopy confirm the successful functionalization of epichlorohydrin and the successful preparation of the AEMs. The ion exchange capacity, water uptake, swelling ratio, mechanical properties, thermal stability, OH− conductivity, morphology and alkaline stability of the AEMs are assessed and compared. The experimental results suggest that the AEM modified by piperidine cation owns continuous ion channels and obvious microphase separation structure, resulting in an OH− conductivity of 94.13 mS cm−1 at 80°C. And its alkali resistance is also relatively good (87.16%, 360 h). Besides, crosslinking by p‐phthalaldehyde effectively lowers the swelling ratio, increases the thermal stability and improves the mechanical properties of the AEMs.
Harmonization of criteria and terminology in fetal rat skeletal evaluations
Authors: Posobiec L. M. , Kopp C. , Murzyn S. M. , Olitan T. , Rendemonti J. , French J. , Tamborini E. , Campey J. , Longo M. , Danberry T. , Vaillancourt M. , Nowland W. , Daoud M. , Qualls C. , Harris S. B. 
Published: May 2023

AbstractBackgroundA survey of laboratories in North American and Europe that routinely conduct fetal skeletal examinations was performed with the purpose of (1) understanding current terminology used for classifying skeletal findings in developmental toxicity (DT) studies and (2) understanding the criteria used to identify relatively common findings that sufficiently deviate from normal. The goal was to promote terminology harmonization and improve interlaboratory consistency in the criteria used to identify developmental anomalies.MethodsThe survey, designed based on terminology for developmental anomalies recommended by an international collaboration (Makris et al., Congenital Anomalies, 2009;49(3):123–246), was conducted by a subgroup (authors of this publication) of the Royal Society of Biology's International Register of Fetal Morphologists (IRFM).ResultsIndividual and summarized anonymized responses are provided here. The authors, who are expert fetal morphologists with experience performing fetal examinations, reviewed the responses and generated recommendations on preferred terminology and criteria for determining when morphological variations deviate from normal and warrant recording of the findings for skeletal observations in Sprague Dawley (SD) fetal rats. The objective of these recommendations is to complement Makris et al. (Congenital Anomalies, 2009;49(3):123–246).ConclusionThe broad application will improve interlaboratory harmonization of recording fetal skeleton findings in developmental toxicity studies intended for regulatory submissions, including SEND (Standard for Exchange of Nonclinical Data).
Successful endoscopic hemostasis for waterfall‐like gastroduodenal artery hemorrhage
Authors: Jinushi Ryuhei , Koizumi Kazuya , Masuda Sakue , Ryozawa Shomei 
Published: May 2023

Key clinical messageEndoscopic hemostasis is the first step in cessation of gastrointestinal bleeding. Although IVR may sometimes be required for preventing rebleeding, prophylactic IVR was not considered necessary in this case because of complete endoscopic hemostasis.
HHV8‐unrelated primary effusion lymphoma in a patient with HBV‐related liver cirrhosis: A case successfully treated with rituximab and lenalidomide
Authors: Liao Peng‐Jun , Yuan Hui , Wei Xiao‐Juan 
Published: May 2023

AbstractHuman herpesvirus type 8 (HHV‐8) unrelated primary effusion lymphoma (PEL) like lymphoma (PEL‐LL) is an exceedingly rare non‐Hodgkin lymphoma with no characteristic symptoms and consensus on the optimal treatment. This case report presents a 55‐year‐old man with prior HBV‐related Child‐Pugh B liver cirrhosis and developing activity‐related dyspnea. A moderate amount of pleural effusion was identified without tumor masses, and cytological studies confirmed a diagnosis of PEL‐LL. The patient received rituximab and lenalidomide, albeit with HBV infection, and is currently on maintenance therapy with resolving symptoms but without HBV reactivation. Hence, the R2 protocol (rituximab and lenalidomide) might be clinically effective and safe for PEL‐LL patients with HBV infection and Child‐Pugh B liver cirrhosis.
Intracranial nasofrontal dermoid cyst and a hair in the nose tip without a sinus tract identified with single‐staged combined approach excision done
Authors: Tam Aurora Ka Yue , Zhu Xian Lun , Chow Samuel Man Wai , Lee Shui Kwong John , Lai Calvin Chee Fung , Chan Kit Ying , Chu Winnie Chiu Wing , Tong Michael Chi Fai 
Published: May 2023

Key Clinical MessageThis is the first reported case of intracranial nasofrontal dermoid without sinus tract, with complete excision done in single‐staged combined approach frontal craniotomy and open rhinoplasty, and satisfactory nasal reconstruction.
Autoimmune hemolytic anemia complicating a chronic neutrophilic leukemia: A case report of a rare association
Authors: Rakez Rim , Charef Ons , Boufrikha Wiem , Rassas Syrin , Boukhriss Sarra , Laatiri Mohamed Adnene 
Published: May 2023

Key Clinical MessageChronic neutrophilic leukemia is a rare disease with a poor prognosis. Its diagnosis is challenging in the lack of genetic tools. It can infrequently be associated with autoimmune hemolytic anemia.AbstractChronic neutrophilic leukemia is a rare disease with poor prognosis, characterized by a sustained mature neutrophilic leukocytosis in the absence of monocytosis or basophilia with few or no circulating immature granulocytes, hepatosplenomegaly, and granulocytic hyperplasia of the bone marrow. In addition, no molecular markers for other myeloproliferative neoplasms are detected. The 2016 WHO classification included the presence of the CSF3R mutation as a key diagnostic criterion for this disease. Although anemia may be present at diagnosis, hemolytic one rarely complicates myeloproliferative neoplasms. Treatment is largely based on cytoreductive agents, but bone marrow allograft remains the only curative option. We report the case of a patient with chronic neutrophilic leukemia associated with autoimmune hemolytic anemia. We describe the epidemiological, clinical, prognostic, and therapeutic features of this disease in addition to the difficulties of its diagnosis and management in Tunisia.
Design of Stable 2D Heterostructured Photocatalyst for Drastically Improved Hydrogen Generation and Unravelling the Underlying Charge Carrier Dynamics
Authors: Kumar Niharika , Mrinalini Madoori , Bastia Sweta , Mishra Rajashree P. , Sahoo Manas K. , Chaudhary Yatendra S. 
Published: May 2023

AbstractThe design of heterostructured photocatalysts comprising of 2‐D mesoporous C3N3 (π‐conjugated bonds with one less nitrogen atom in the ring to promote the better electron transport unlike conventional g‐C3N4) donor coupled with the MoS2 acceptor by a template‐directed thermal synthesis followed by hydrothermal synthesis is presented. The formation and coupling of MoS2 through basal planes on the surface of mpg‐CN has been confirmed by the XRD, XPS (C/N ratio of the order of 1), and lengthening of the C−N bond as revealed by increasing intensity of FTIR peak (1232 cm−1), respectively. Upon optimization, MS‐mpg‐CN exhibits 10‐fold enhancement in hydrogen generation rate and efficiency (∼86500 μmolg−1 h−1, IPCE: ∼64 %) than that of observed for MS‐mpg‐C3N4 photocatalyst (∼8250 μmolg−1 h−1, IPCE: ∼5.6 %). The lower PL emission intensity, average lifetime (1.91 ns) of charge carriers, precise semicircle in Nyquist plot and higher degree of band bending (Efb −0.64 eV), higher ‘g’ value (2.0038) in the EPR imply improved charge carrier separation, transfer kinetics and formation of intimate heterojunction, respectively. Furthermore, hydrogen evolution measured for subsequent days while reusing photocatalyst shows no significant change in the activity (∼1.2 % variation over three consecutive cycles), confirming their photostability and reusability.
Ligand‐Directed H2S Probe and Scavenger for Specific Tumor Imaging
Authors: Cai Xuekang , Zhang Jingming , Ye Haishun , Cui Kai , Hao Tingting , Yi Long , Yang Xing 
Published: May 2023

AbstractAn expanding body of evidence suggests that specifically targeting hydrogen sulfide (H2S) might potentially benefit both tumor diagnosis and treatment, but there is still a lack of cancer‐targeted molecular tools for in vivo applications. Here, we report the first ligand‐directed H2S‐specific near‐infrared fluorescent sensor PSMA‐Cy7‐NBD and scavenger PSMA‐Py‐NBD that target the prostate‐specific membrane antigen (PSMA). PSMA‐Cy7‐NBD displays a 53‐fold off–on fluorescence response to H2S at 803 nm with high specificity. PSMA‐Py‐NBD can scavenge H2S fast (k2=30.8 M−1 s−1 at 25 °C) without interference from biothiols. Both tools are highly water‐soluble and can be transported selectively into PSMA‐expressing prostate cancer cells. Endogenous H2S levels in murine 22Rv1 tumor models can be imaged and downregulated by intravenous injection of PSMA‐Cy7‐NBD and PSMA‐Py‐NBD, respectively. These tools could potentially help to investigate H2S cancer biology and with related therapies.
Picolinaldehyde‐Zinc(II)‐Palladium(0) Catalytic System for the Asymmetric α‐Allylation of N‐Unprotected Amino Esters
Authors: Li Qian , Liu Yan , Li Can 
Published: May 2023

AbstractReported in this work is a synergistic ternary achiral picolinaldehyde‐Zn(II)‐chiral palladium complex system for the highly enantioselective α‐allylation of N‐unprotected amino esters. By utilizing a variety of allylic carbonates or vinyl benzoxazinanones as substrates, α‐allyl α‐amino esters were obtained in high yields (up to 96 %) with high enantioselectivities (up to 98 % ee). Control experiments suggest that the coordination of Zn(II) with the Schiff base intermediate enhances the acidity of the α‐C−H bonds of amino esters, thereby favoring α‐allylation over intrinsic N‐allylation. Furthermore, NMR studies reveal an interaction between the chiral palladium complex and the Zn(II)‐Schiff base intermediate, leading to the formation of a picolinaldehyde‐Zn(II)‐Pd(0) catalytic system.
Short‐term and long‐term effect of nutrition intervention in the Linxian Dysplasia Nutrition Intervention Trial and the reason for disappearance of the intervention effect: A cohort study
Authors: Fan Jin‐hu , Sun Wan‐yi , Yang Huan , Wang Xiao‐kun , Abnet Christian C. , Qiao You‐lin 
Published: May 2023

AbstractBackgroundThe objective of this study was to determine the short‐term and long‐term effects of a nutrition intervention in using 37 years of follow‐up data.MethodsThe Linxian Dysplasia Population Nutrition Intervention Trial was a randomized, double‐blind, placebo‐controlled trial with 7 years of intervention and 30 years of follow‐up. The Cox proportional hazard model was used for analyses. Subgroup analyses were conducted in age and sex subgroups, and the 30 years of follow‐up were divided into two 15‐year early and late periods.ResultsThe results at 37 years did not indicate any effects on mortality from cancers or other diseases. In the first 15 years, the intervention decreased the overall risk of gastric cancer deaths in all participants (hazard ratio [HR], 0.76; 95% confidence interval [CI], 0.58–1.00) and in the subgroup participants younger than 55 years (HR, 0.64; 95% CI, 0.43–0.96). In addition, in the group younger than 55 years (HR, 0.58; 95% CI, 0.35–0.96), the intervention decreased the risk of death from other diseases; and, in the group aged 55 years and older (HR, 0.75; 95% CI, 0.58–0.98), the intervention reduced the risk of death from heart disease. There were no significant results in the later 15 years, which indicated the disappearance of the intervention effect. Comparing demographic characteristics between those who died during the two periods, the participants who died later included more women, had a higher education level, had a lower smoking rate, were younger, and also more had a mild degree of esophageal dysplasia, representing a better lifestyle and health condition.ConclusionsLong‐term follow‐up indicated no effect of nutrition on deaths in a population with esophageal squamous dysplasia, further supporting the significance of continuous nutritional intervention for cancer protection. The pattern of protective effect of a nutrition intervention on gastric cancer in patients with esophageal squamous dysplasia was similar to that in the general population. Participants who died in the later period had more protective factors than those who died in the earlier period, contributing to the obvious effect of the intervention in early stage disease.
The feasibility, acceptability, and preliminary efficacy of a self‐advocacy serious game for women with advanced breast or gynecologic cancer
Authors: Thomas Teresa Hagan , Bender Catherine , Donovan Heidi S. , Murray Patty Jo , Taylor Sarah , Rosenzweig Margaret , Sereika Susan M. , Brufsky Adam , Schenker Yael 
Published: May 2023

AbstractBackgroundCancer clinicians and systems aim to provide patient‐centered care, but not all patients have the self‐advocacy skills necessary to ensure their care reflects their needs and priorities. This study examines the feasibility, acceptability, and preliminary efficacy of a self‐advocacy serious game (an educational video game) intervention in women with advanced breast or gynecologic cancer.MethodsWomen with recently diagnosed (<3 months) metastatic breast or advanced gynecologic cancer were randomized 2:1 to receive a tablet‐based serious game (Strong Together) (n = 52) or enhanced care as usual (n = 26). Feasibility was based on recruitment, retention, data completion, and intervention engagement. Acceptability was assessed via a postintervention questionnaire and exit interview. Preliminary efficacy was assessed on the basis of change scores from baseline to 3 and 6 months in self‐advocacy (Female Self‐Advocacy in Cancer Survivorship Scale) using intention‐to‐treat analysis.ResultsSeventy‐eight women (55.1% with breast cancer; 44.9% with gynecologic cancer) were enrolled. Feasibility was demonstrated by satisfactory recruitment (69% approach‐to‐consent rate; 93% enroll‐to‐randomize rate), retention (90% and 86% at 3 and 6 months, respectively; 85% data completion), and intervention engagement (84% completed ≥75% of the game). Participants endorsed the intervention’s (75%) and trial’s (87%) acceptability. Participants in the intervention group experienced significant improvements in self‐advocacy at 3 and 6 months compared to participants in the control group.ConclusionsStrong Together is feasible and acceptable among women with advanced breast or gynecologic cancer. This intervention demonstrates promising evidence of clinical efficacy. A future confirmatory trial is warranted to test the efficacy of the intervention for patient and health system outcomes.
Distributed structural clustering on large graph
Authors: Rong Chuitian , Zhou Jinyu 
Published: May 2023

SummaryGraph clustering is a primitive operation for graph data mining. It plays an important role to reveal community clusters, hubs, and outliers in complex networks. There are several graph clustering algorithms have been proposed based on the well‐studied SCAN algorithm in recent years. However, SCAN and its improved sequential variants are prohibitively slow due to their iterative computations. The parallel variants are focusing on improving the efficiency of graph clustering by utilizing multi‐cores computer architectures on single computing node with complex optimization techniques. Therefore, SCAN and its variants are not suitable for processing very large graphs due to the limitations of memory size and storage volume on a single node. In this article, we proposed a distributed parallel structural clustering algorithm using MapReduce. In order to improve the efficiency further, we proposed optimization techniques including partition based clustering and simplified combination with labels to accelerate the operations. We conducted extensive experiments on real world datasets. The experimental results showed our algorithm is high efficiency and scales well under different settings.