bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh dosis pupuk organik kasgot terhadap karakter agronomi dan hasil tanaman bayam (Amaranthus tricolor)
Authors: Purwanto Purwanto , Kharisun Kharisun , Ismangil Ismangil , Kusumo Ruly Eko Kurniawan , Noorhidayah Ratri 
Published: July 2023

Increasing soil fertility through the application of organic fertilizers is important, and the newest organic fertilizer source is maggot frass. This study aimed to examine the effectiveness of maggot frass on the growth and yield of spinach plants. Research was conducted in the Agronomy and Horticulture Laboraty, and Experimental Field Faculty of Agriculture Universitas Soedirman from October - December 2022. This research was an experimental study and used a Randomized Block Design with three replications. The standard fertilizers used were 150 kg ha-1 urea, 150 kg ha-1 SP-36, and 100 kg ha-1 KCl. The treatments tried included K0: control, K1: standard fertilization, K2: 1 t ha-1, K3: 2 t ha-1, K4: 4 t ha-1, K5: 8 t ha-1, K6: 16 t ha -1, K7: 32 t ha-1, and K8: 64 t ha-1. The results showed that the application of maggot frass starting at a dose of 2 t ha-1 was able to increase the yield of spinach plants. The highest yield was achieved at a dose of 64 t ha-1 of 18.85 t ha-1. These results have implications that maggot frass can be used as a source of organic fertilizer with application doses starting at 2 t ha-1.ABSTRAK Kesuburan tanah sangat berpengaruh terhadap hasil tanaman bayam. Peningkatan kesuburan tanah melalui aplikasi pupuk organik menjadi penting, dan sumber pupuk organik terbaru adalah kasgot. Penelitian ini bertujuan untuk mengkaji efektivitas pupuk kasgot terhadap pertumbuhan dan hasil tanaman bayam. Penelitian dilakukan di Laboratorium Agronomi dan Hortikultura, dan Kebun Percobaan Fakultas Pertanian Universitas Soedirman pada Oktober - Desember 2022. Penelitian ini merupakan penelitian eksperimental dan menggunakan Rancangan Acak Kelompok (RAK) dengan tiga kali ulangan. Perlakuan yang dicoba adalah dosis pupuk kasgot. Pupuk standar yang digunakan adalah urea 150 kg ha-1, SP-36 150 kg ha-1, dan KCl 100 kg ha-1. Perlakuan yang dicoba antara lain K0: control, K1: pemupukan standar, K2: 1 t ha-1, K3: 2 t ha-1, K4: 4 t ha-1, K5: 8 t ha-1, K6: 16 tha-1, K7: 32 t ha-1, dan K8: 64 t ha-1. Hasil penelitian menunjukkan aplikasi pupuk organik kasgot mulai dosis 2 t ha-1 sudah mampu meningkatkan hasil tanaman bayam dibandingkan kontrol maupun pemupukan standar. Hasil tertinggi dicapai pada dosis 64 t ha-1 sebesar 18,85 t ha-1. Aplikasi kasgot layak secara teknis agronomi. Hasil ini memberikan implikasi bahwa kasgot dapat dijadikan sebagai sumber pupuk organik dalam budidaya tanaman bayam dengan dosis aplikasi mulai 2 t ha-1.
Evaluasi keragaman genetic berbagai galur murni jagung manis utnuk penentuan tetua hibrida
Authors: Ritonga Arya Widura , Sulistyowati Dwiwanti , Budiman Candra , Zamzami Ahmad , Permatasari Okti Syah Isyani 
Published: July 2023

Sweet corn is one of the most popular crops in Southeast Asian countries, including Indonesia. Superior sweet corn varieties breeding is important to do in order to improve the quality and productivity of sweet corn in Indonesia. Plant breeding programs rely on genetic quality variability and heritability information. Therefore, this study aimed to evaluate the performance and genetic variablity of various sweet corn inbred lines to determine the best prospective parents for hybridization. The study was conducted at the Leuwikoppo experimental field of the Department of Agronomy, Faculty of Agriculture, IPB, from January to March 2022. Twelve sweet corn inbred lines were planted in the field using a completely randomized block design with three replications. Analysis of variance, estimation of the genetic parameters, broad sense heritability, genetic and phenotypic coefficients variability and cluster analysis were carried out in this study. The results showed that there were differences in qualitative and quantitative characters between the tested sweet corn genotypes. Plant height, ear height, stem diameter, ear length, and ear weight had a high broad sense heritability and moderate to high of genetic coefficients of variability. SM12-2 and T10-3 lines become the prospective parents generating a high cob weight and seed sweetness.ABSTRAK Jagung manis merupakan salah satu tanaman yang sangat populer di negara-negara Asia tenggara, termasuk Indonesia. Hal ini menjadikan perakitan varietas unggul jagung manis dengan produktivitas dan kualitas tinggi perlu dilakukan. Informasi keragaman genetik sangat penting dalam program pemuliaan tanaman. Penelitian ini bertujuan untuk mengevaluasi keragaan dan keragaman genetik berbagai galur jagung manis sehingga dapat diperoleh tetua potensial untuk pembentukan hibrida F1 jagung manis. Percobaan dilakukan di Kebun Percobaan Leuwikoppo, Departmen Agronomi, Fakultas Pertanian, IPB, dari bulan Januari sampai Maret 2022. Sebanyak 12 galur murni jagung manis ditanam menggunakan rancangan kelompok lengkap teracak dengan 3 ulangan. Data diolah dengan menggunakan analisis ragam, pendugaan parameter genetik komponen ragam, heritabilitas arti luas, koefisien keragaman genotipik dan fenotipik serta analisis kluster. Hasil penelitian menunjukkan adanya perbedaan pada karakter kualitatif dan kuantitatif diantara galur jagung manis yang diuji. Selain itu, diperoleh informasi bahwa karakter tinggi tanaman, tinggi tongkol, diameter batang, panjang tongkol, dan bobot tongkol memiliki nilai heritabilitas yang tinggi serta nilai koefisien keragaman genetik kategori moderat sampai tinggi. Berdasarkan penelitian ini, galur jagung manis SM12-2 dan T10-3 merupakan tetua yang potensial menghasilkan bobot tongkol dan kemanisan biji yang tinggi.
Da’wah Strategy for Jabatan Hal Ehwal Agama Islam Negeri Sabah (JHEAINS) in the Tuaran Region Towards Muallaf
Authors: Jusup Nurshaiera Binti 
Published: July 2023

Jabatan Hal Ehwal Islam Negri Sabah (JHEAINS) is a da'wah organization that operates in society. This research aims to discover the da'wah strategy used by the Tuaran section of JHEAINS in its da'wah efforts against Muslim converts. This research analyses the methods, approaches and obstacles to JHEAINS' da'wah towards Muslim converts. The technique used in this research is descriptive; this method aims to systematically describe specific facts factually and carefully using observation, interviews and documentation techniques. The research results show that JHEAINS uses several da'wah methods with Fardhiyyah, tarbiyyah, al-Ardiyyah, al-Bi'thiyyah, al-Mujadalah and counselling approaches. Even so, the JHEAINS organization faces several obstacles in preaching to Muslim converts. This research has significant implications, especially for converts and preachers in the JHEAINS organization spreading da'wah in Tuaran.
Examination of Placental Dysfunction and Neonatal Outcomes in Hospitalized Patients who have Hyperemesis Gravidarum Diagnosis
Authors: ERİÇ HORASANLI Jule , ŞENGÜL Nurullah 
Published: July 2023

Background: Evidence on the effect of hyperemesis gravidarum (HG) on pregnancy outcomes is still unclear. In this study, placenta-related dysfunctions and neonatal outcomes in patients who were hospitalized with HG were retrospectively analyzed.
Methods: This study was conducted retrospectively among women who had singleton deliveries in our hospital between January 2015 and January 2020. As the case group, women with singleton pregnancies who were hospitalized due to HG and delivered were included. The control group consisted of women with singleton pregnancies who delivered without hospitalization due to HG. Through the hospitalization files of the patients who were hospitalized due to HG and not hospitalized due to HG, neonatal outcomes such as placental dysfunction, including gestational diabetes, gestational hypertension, preeclampsia, or stillbirth, and low birth weight, small for gestational age (SGA), preterm birth (PTB), the necessity for neonatal intensive care, 5-min Apgar scores, were examined.
Findings: The mean gestational age was determined as 37.7 ± 1.5 weeks in the HG group and 37.8 ± 1.4 weeks in the control group. The mean week of gestation upon hospitalization for HG was 10.6 ± 3.6 weeks. There was no significant difference between the groups regarding preeclampsia, PTB, postpartum hemorrhage, birth weight, GDM, or neonatal intensive care unit requirement. It was found that SGA babies with abnormal birth weights were seen more frequently in the deliveries of patients hospitalized for HG (P = 0.022). The 5-min Apgar scores were higher in the deliveries of patients hospitalized for HG than in the control group (P = 0.004).
Conclusion: It was concluded that hospitalizations due to HG do not pose a risk of placental dysfunction. Of the neonatal outcomes, SGA was more common in the infants of mothers with HG. Contrary to the expectations herein, the 5-min Apgar scores were higher in hospitalized patients for HG.
Lymphadenopathies associated with Cat-Scratch Disease in Turkiye
Authors: YAHŞİ Aysun , YAZICIOĞLU Bahadır 
Published: July 2023

Aim: Bartonella henselae is the etiologic agent of cat-scratch disease. The disease affects children and young adults. The objective of this study is to analyze the epidemiology, clinical features, and course of this disease in Turkiye.
Materials and Methods: Children without immunodeficiency, with relevant clinical signs and symptoms, and positive serology were included in the study. Clinical, demographic and laboratory data of patients diagnosed with cat-scratch disease between October 2018 and February 2021 were evaluated retrospectively.
Results: A total of 46 patients were included. The mean age was 132 months (IQR 90- 153 months), and 69.6% (n = 32) were male. There was a history of cat contact in 73.9% of the patients and 43.5% of these were with household cats. Most of the lymphadenopathies were axillary (73.9%), and generalized lymphadenopathy was not observed. The median duration of symptoms before admission was 4 weeks. The median ultrasonographic lymphadenopathy size was 4 cm. The median clinical improvement time was 6.5 weeks. Azithromycin was given in 18 patients and intravenous and/or oral beta-lactamase inhibitor combination therapy in 18 patients while no treatment was necessary in 10 patients.
Conclusion: The typical presentation is a solitary, enlarged lymph node, mostly in the axillary region. Bartonella henselae IgG level should be studied prior to invasive procedures. It should be known that cat scratch disease can develop without a history of cat contact. Meanwhile, it should be known that contact with a house cat may cause disease more often than contact with street cats.
Changes in the ubiquitination system in children with cerebral palsy
Authors: DOĞAN Ayşe Gülşen , ÇETİN İhsan 
Published: July 2023

Objective: We aimed to investigate the levels of Ubiquitin Carboxy Terminal Hydrolase-L1 enzyme (UHC-L1), Transactive Response DNA Binding Protein-43 (TDP-43) and Cullin-3 in peripheral blood associated with ubiquitination processes in children with cerebral palsy (CP).
Materials and Methods: We included 50 children with CP in the first patient group. In the control group, there were 30 healthy children who were matched with the patient groups in terms of age and gender. We also recorded risk factors for CP, CP type, botox application, orthosis use, maternal age at birth, and additional problems. Patients aged 6-10 years, diagnosed with CP, without genetic, metabolic disease or mental retardation history were included in this study.
Results: There were 32 female and 18 male patients in the CP group, while there were 19 female and 11 male volunteers in the control group. Maternal age was significantly higher in the CP group (p=0.002). In our study, as a result of the comparison between the control group and the CP group in terms of UCH-L1, TDP-43 and Cullin 3 levels; the levels of UCH-L1 (p=0.048), TDP-43 (p=0.028) and Cullin 3 (p=0.042) in the CP group were found to be statistically significantly lower than the levels of the control group.
Conclusion: The low serum concentrations of UCHL-L1, Cullin 3 and TDP-43 molecules in the CP group and the statistically positive correlation of these molecules with each other may help to understand the neuronal pathophysiology after disruption of the ubiquitination system.
Relationship Between Prolonged Jaundice and Vitamin B12 Levels in Term Newborn
Authors: YALINBAŞ Emine Esin , DURMAZ Yaşar , MUTLU Fezan 
Published: July 2023

Abstract
Aim: Vitamin B12 deficiency, when observed during the neonatal period, can generally be traced back to maternal causes. In cases of vitamin B12 deficiency, hyperbilirubinemia may occur due to hem overproduction as the result of erythrocyte lysis. Prolonged jaundice is common during the neonatal period, and its underlying etiological causes should be analyzed. The aim of this study was to analyze whether vitamin B12 deficiency has any effect on prolonged jaundice formation in infants.
Material and Method: The study examined 89 infants; this included 45 that had been diagnosed with prolonged jaundice and 44 in the control group. Their clinical and demographic characteristics were recorded. Patient group was formed with term infants with prolonged jaundice excluding possible etiological causes of prolonged jaundice. Both the maternal and infant vitamin B12 levels were analyzed.
Results:An indirect bilirubin level of 11.8 mg/dl in the prolonged jaundice group and 3.16 mg/dl (p < 0.001), a hemoglobin level of 14.18 gr/dl and 15.7 gr/dl (p = 0.005), and infant vitamin B12 level of 168 pg/ml and 205.2 pg/ml (p=0.013) in the patient and control groups, respectively, showed significant differences between the two. Maternal vitamin B12 levels were found to be similar in the patient and control groups (p= 0.315), and there was no significant correlation between the vitamin B12 levels of the infants and mothers (r = 0.278, p = 0.064).
Conclusion: Vitamin B12 deficiency can be related to prolonged jaundice in neonatals, and an early diagnosis of vitamin B12 deficiency in high risks group in the neonatal period can be useful in terms of potentially identifying and controlling related conditions.
Keywords: Jaundice, newborn, vitamin B12 deficiency
ASSOCIATION OF TOLL-LIKE RECEPTOR 9 EXPRESSION WITH PROGNOSIS IN BREAST CARCINOMA
Authors: ÇELİK Zeliha Esin , DEMİR Fatih , YONAR Harun , ÇELİK Murat , EREN Orhan Önder 
Published: July 2023

Aim:
Breast cancer (BC) is a common malignancy in women. Some molecules including TLR9 are still under investigation as potential prognostic factors in BC. In the present study, we aimed to determine the relation between TLR9 expression and clinicopathological prognostic parameters and survival in BC.

Materials and methods:
One hundred and thirty nine patients diagnosed as BC included the present study. Immuno-reactivity scoring (IRS) system was used to reveal the tissue TLR9 expression levels.

Results:
We found higher TLR9 expression in tumors diagnosed as invasive carcinoma NOS, grade 3 tumors, tumors with necrosis, ER negative and Her2 positive tumors and tripple negative molecular subtype. Furthermore, tumors with low TLR9 scores showed increased overall survival compared to tumors with high TLR9 scores.

Conclusions:
TLR9 overexpression in BC is associated with some prognostic parameters including histologic type, tumor grade, tumor necrosis, ER and Her2 status and molecular subtype as well as overall survival. Further studies with larger patient series are needed to shed light on the use of TLR9 as a clinical and therapeutic target in BC.
Monitoring seasonal variations of haloacetic acids (HAAS) in low-TOC and low-chlorine networks and assessing risk to public health: Muş, Türkiye case
Authors: Edip Avşar  , Adile Kılıç  
Published: July 2023

Chlorine not only removes parasitic pathogenic microorganisms in water, but also causes the formation of disinfection by-products (DBPs) that can be carcinogenic to humans, due to reacting with natural organic matter (NOMs) in raw water sources. Haloacetic acids (HAAs) are one of the most well-known and common disinfection by-product groups (DBPs) in the literature. In the risk definitions of the EPA, some of its components have been identified as carcinogenic. Therefore, determination of HAA concentration in water and execution of a risk analysis are very important in terms of determining the possible effects on public health. This study aimed to monitor the seasonal and spatial variations of haloacetic acids (HAAs) in 2 different water supplies (surface and groundwater) serving the city center of Muş Province, Türkiye, and to demonstrate their public health implications. In this context, an analytical study was conducted covering 4 seasons. According to the results, although the amount of NOM in water bodies was less than 1 mg‧L−1, the HAA5 content may occasionally exceed the USEPA limits of 60 µg‧L−1, but did not exceed the Canadian 80 µg‧L−1 limit. When the WHO limit values were examined on a component basis, it was determined that the MCAA concentrations in both water sources sometimes exceeded the limit of 20 µg‧L−1 in the July and October sampling periods. The risk level related to maximum DCAA level in the main network by means of ingestion pathway was found to be 18.7 times higher for women and 16.5 times higher for men when compared with USEPA risk criteria. Also, in the Muratpaşa water network, risk from DCAA exceeds the USEPA risk level 15.2-fold in women and 13.4-fold in men. However, since it was also found that the level of free chlorine in the network does not meet the required level, it should be noted that there may be an increase in the risk level if there is adequate chlorination in the supply.
Pengembangan Media Interaktif pada Materi Bangun Ruang Menggunakan Adobe Animate di Kelas V
Authors: Amin Filzah Izzati , Sumarni Sri , Somakim Somakim 
Published: July 2023

The use of interactive multimedia has a big impact on education, especially on the mathematics of parts, properties of blocks and cubes. This research aims to produce valid, practical, and effective multimedia. Class V B students of SD Negeri 109 Palembang are the subjects of the field test. The concept of modification of Hannafin and Peck's development pattern is the pattern used in this study, which has 3 stages, namely analyzing needs, outlines, and development and implementation with evaluation and revision at each stage. Tests on materials, designs, and media were carried out by experts and were declared very valid after revising the product. Multimedia is declared practical after a formative evaluation based on the acquisition of a very practical classification. Multimedia learning mathematics is effectively implemented in accordance with the learning outcomes of class VI B students at SD Negeri 109 Palembang. After being reviewed through the results of the percentage of 90% of children successfully achieving the KKM standard and the average value of N-gain is 0.54 with a medium classification. Pemanfaatan multimedia interaktif berpengaruh besar pada pendidikan, terutama pada matematika materi bagian-bagian, sifat-sifat bangun ruang balok dan kubus. Riset ini bertujuan yaitu menghasilkan multimedia yang valid, praktis, dan efektif. Siswa kelasV B SD Negeri 109 Palembang merupakan subjek dari uji lapangan. Konsep modifikasi pola pengembangan Hannafin dan Peck adalah pola yang digunakan pada penelitian ini, yang mempunyai 3 tahapan yakni menganalisis kebutuhan, kerangka bentuk, dan pengembangan beserta penerapan dengan evaluasi dan revisi di setiap tahapnya. Pengujian terhadap materi, desain, dan media dilakukan kepada ahli dan dinyatakan sangat valid setelah melakukan revisi produk. Multimedia dinyatakan praktis setelah dilakukan evaluasi formatif berdasarkan perolehan klasifikasi sangat praktis. Multimedia pembelajaran matematika efektif dilaksanakan sesuai dengan hasil pembelajaran peserta didik kelas VI B di SD Negeri 109 Palembang. Setelah ditinjau melalui hasil persentase 90% anak berhasil tercapai standar KKM serta besaran nilai rerata N-gain adalah 0,54 dengan klasifikasi sedang.
Astudy on prognostic significance of neutrophil-lymphocyte ratio in patients with stemi
Authors: M Nallathambi , G Anurekha , C Paranthakan 
Published: July 2023

Atherosclerosis, the clinically manifested form of cardiovascular disease (CVD), mainly accounts for most deaths worldwide. Inflammatory disorders that elevate CVD risk have been associated with circulating inflammatory markers that encompass neutrophil-lymphocyte ratio (NLR), which could be employed as an economical prognostic tool for the diagnosis of the same. Hence, this study focused on assessing the extrapolative implication of NLR among ST-Elevation Myocardial Infarction (STEMI) patients. The observational study included 55 STEMI patients (Mean age – 52.08 years) at Thanjavur medical college (December 2015 to February 2016). The patients were delineated into two groups based on NLR values (high &#62;3.0 and low &#60;3.0). Among the 55 patients, the post-MI complication was observed in 44 subjects, among which 10% of them expressed a high NLR value. A notable proportion of patients displaying arrhythmia and LV dysfunction had higher NLR values.Henceforth, the study reveals the independent and vital prognostic association between NLR and atherosclerosis that could be designated as a reliable marker in the early diagnosis of the disease as well post MI complications.
Is fixed dose combination of rosuvastatin with fenofibrate more effective than high dose Rosuvastatin inpatients with stable coronary artery disease with mixed dyslipidemia? A study
Authors: Bharti Rupendra Kumar , Kosawara Pratima , Negi P S , Kaundal P K 
Published: July 2023

: We aimed to compare lipid lowering efficacy and safety of fixed dose combination (FDC) of rosuvastatin and fenofibrate with high dose rosuvastatin (HDR) in patients of stable coronary artery disease (CAD) with mixed dyslipidemia.: 165 patients with stable CAD with mixed dyslipidaemia were randomly assigned to HDR group, 40mg per day (n=79) and FDC group; fenofibrate with rosuvastatin, 145 mg and 20 mg per day respectively (n=88). The lipid profile was measured at baseline and at 12 weeks. The safety profile was measured by recording self-reported adverse reactions during follow up visits and by measuring serum levels of transaminases, creatinine phosphokinase (CPK) at 4 weeks. The lipid lowering efficacy was compared by estimating differences in percentage mean change from baseline values of the lipid fractions and percentage of patients achieving target goals between study groups using unpaired t test and Xtest respectively. : The FDC achieved greater reduction compared to HDR in LDL-C, -11.0% 95% C.I. (-17.7% to -4.3%) p&#60;0.001, NHDL-C levels, -10.1% (-16.0% to -4.2%) p&#60;0.001, triglyceride, -18.4% (-32.0% to -4.7%) p&#60;0.0001. The increase in HDL-C was significantly higher in FDC arm, 14.9% (8.3% to 21.4%) p&#60;0.001.The percentage of patients achieving LDL-C and Non HDL-C target goals were higher in FDC arm but difference was statistically not significant. The FDC was tolerated well than HDR regimen. : The combination of moderate dose rosuvastatin and fenofibrate is more effective in reducing atherogenic lipid fractions and increasing the HDL-C level compared to high dose rosuvastatin and had better safety profile.