bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distributed fixed-time control for six-degree-of-freedom spacecraft formation with event-triggered observer
Authors: Zhang J. , Xia H. , Li Z. 
Published: June 2023

AbstractThe paper addresses the six-degree-of-freedom coupled control problem for spacecraft formation flying subject to actuator saturation and input quantisation whilst considering limited communication resources. Firstly, a novel event-triggered distributed observer without continuous communications is presented to recover the information of the virtual leader. Remarkably, by embedding a hyperbolic tangent function-based nonlinear term into the triggering condition, the event-based observer realises a more reasonable trigger threshold. Subsequently, an adding-a-power-integrator-based fixed-time control algorithm is proposed for the follower spacecraft. Further, the control scheme ingeniously compensates for the actuator saturation and the input quantisation problems without embedding auxiliary systems. Finally, numerical simulations are carried out to highlight the advantages of the theoretical results.
Enhancing an enterprise data warehouse for research with data extracted using natural language processing
Authors: Magoc Tanja , Everson Russell , Harle Christopher A. 
Published: June 2023

Abstract

Objective:
This study aims to develop a generalizable architecture for enhancing an enterprise data warehouse for research (EDW4R) with results from a natural language processing (NLP) model, which allows discrete data derived from clinical notes to be made broadly available for research use without need for NLP expertise. The study also quantifies the additional value that information extracted from clinical narratives brings to EDW4R.

Materials and methods:
Clinical notes written during one month at an academic health center were used to evaluate the performance of an existing NLP model and to quantify its value added to the structured data. Manual review was utilized for performance analysis. The architecture for enhancing the EDW4R is described in detail to enable reproducibility.

Results:
Two weeks were needed to enhance EDW4R with data from 250 million clinical notes. NLP generated 16 and 39% increase in data availability for two variables.

Discussion:
Our architecture is highly generalizable to a new NLP model. The positive predictive value obtained by an independent team showed only slightly lower NLP performance than the values reported by the NLP developers. The NLP showed significant value added to data already available in structured format.

Conclusion:
Given the value added by data extracted using NLP, it is important to enhance EDW4R with these data to enable research teams without NLP expertise to benefit from value added by NLP models.
Helicobacter pylorivirulence factors: subversion of host immune system and development of various clinical outcomes
Authors: Mohammadzadeh Roghayeh , Menbari Shaho , Pishdadian Abbas , Farsiani Hadi 
Published: June 2023

AbstractHelicobacter pylori(H. pylori) is a worldwide spread bacterium, co-evolving with humans for at least 100 000 years. Despite the uncertainty about the mode ofH. pyloritransmission, the development of intra-gastric and extra-gastric diseases is attributed to this bacterium. The morphological transformation and production of heterogenic virulence factors enableH. pylorito overcome the harsh stomach environment. Using numerous potent disease-associated virulence factors makesH. pyloria prominent pathogenic bacterium. These bacterial determinants are adhesins (e.g., blood group antigen-binding adhesin (BabA)/sialic acid-binding adhesin (SabA)), enzymes (e.g., urease), toxins (e.g., vacuolating cytotoxin A (VacA)), and effector proteins (e.g., cytotoxin-associated gene A (CagA)) involved in colonisation, immune evasion, and disease induction.H. pylorinot only cleverly evades the immune system but also robustly induces immune responses. This insidious bacterium employs various strategies to evade human innate and adaptive immune responses, leading to a life-long infection. Owing to the alteration of surface molecules, innate immune receptors couldn't recognise this bacterium; moreover, modulation of effector T cells subverts adaptive immune response. Most of the infected humans are asymptomatic and only a few of them present severe clinical outcomes. Therefore, the identification of virulence factors will pave the way for the prediction of infection severity and the development of an effective vaccine.H. pylorivirulence factors are hereby comprehensively reviewed and the bacterium evasion from the immune response is properly discussed.
Timing fluctuation correction for the front end of a 100-PW laser
Authors: Li Hongyang , Liu Keyang , Wang Xinliang , Liu Xingyan , Meng Xianze , Liu Yanqi , Song Liwei , Leng Yuxin , Li Ruxin 
Published: June 2023

Abstract
The development of high-intensity ultrafast laser facilities provides the possibility to create novel physical phenomena and matter states. The timing fluctuation of the laser pulses is crucial for pump–probe experiments, which is one of the vital means to observe the ultrafast dynamics driven by intense laser pulses. In this paper, we demonstrate the timing fluctuation characterization and control of the front end of a 100-PW laser that is composed of a high-contrast optical parametric amplifier (seed) and a 200-TW optical parametric chirped pulse amplifier (preamplifier). By combining the timing jitter measurement with a feedback system, the laser seed and preamplifier are synchronized to the reference with timing fluctuations of 1.82 and 4.48 fs, respectively. The timing system will be a key prerequisite for the stable operation of 100-PW laser facilities and provide the basis for potential pump–probe experiments performed on the laser.
Decolonizing Allyship and Settler Support for Indigenous Climate Justice: A Note of Thanks to Andrea Sullivan-Clarke
Authors: Smith Andrew Frederick 
Published: June 2023

AbstractI've been thinking quite a lot of late about how, as a settler, I can more fully and effectively support Indigenous peoples struggling for climate justice. In the process, I've found Andrea Sullivan-Clarke's recent insights about decolonizing allyship most helpful. After offering a brief summary of the necessary and sufficient conditions Sullivan-Clarke identifies for decolonizing allyship, I reflect on how I personally can strive to meet these conditions while remaining aware that—like my recovery from alcoholism—my work will never be complete.
Toril Moi's Phenomenological Account of “Woman” and Questions of Trans Inclusivity
Authors: Neuhann Esther Lea 
Published: June 2023

AbstractThe recent debate in feminist philosophy about an adequate concept of woman presupposes the distinction between sex and gender, and most proposals operate on the gender level. Building on Simone de Beauvoir, Toril Moi suggested an account of “woman” that does not rely on the distinction between sex and gender (Moi 1999a). She criticizes that this distinction suggests too strong a separation between the bodily and social dimensions of a person's identity. Instead, her account of “woman” centers around the phenomenological concept of the “body as situation” or the lived/living body (Leib). This understanding of the body emphasizes a person's subjective experience of their own body rather than a third-personal (for example, medical) perspective on humans’ bodies. With her proposal, Moi aims, on the one hand, to resist biological determinism, and, on the other, to avoid the dualism of the sex/gender distinction. In this article, I re-introduce Moi's position to the recent debate and examine how it fares regarding the “inclusion problem” (Katharine Jenkins) toward trans women. I suggest that Moi's account provides resources for an attractive, individualistic, and hence inclusive account of embodied gender identity. For political purposes, however, we also need to analyze concrete contexts of gender-related oppression.
New specimens of Cyclocystoides scammaphoris (Echinodermata) from the Upper Ordovician rocks of the American midcontinent with implications for cyclocystoid functional morphology
Authors: Kolata Dennis R. , Frank Terry , Kaplan Asa , Guensburg Thomas E. 
Published: June 2023

AbstractNew specimens of Cyclocystoides scammaphoris Smith and Paul, 1982, are here reported from the Upper Ordovician Platteville Formation of northern Illinois, Plattin and Decorah groups of east-central Missouri, and Lebanon Limestone of central Tennessee. These fossils reveal skeletal details that provide insight into the anatomy of cyclocystoids. Of particular significance is a network of channels that likely originate near the center of the central disk and extend along the oral side of the radial plates, bifurcating distally two or three times before entering the radial facets on the proximal surface of each marginal ossicle. From here, the network enters a series of facet canals that extend upward through each marginal ossicle, exiting in a linear row of pores. The canals are very similar in size and distribution to the nerve canals in living echinoderms. The axes of the canals, which number up to 500 in some specimens, and those of the radial ducts project proximally away from the oral surface at an elevation angle of about 25°, apparently forming a network that could have converged within the upper part of the body cavity. This origin and function are made clear by the connection between the channel on each radial plate and the radial facet canal pores within each marginal ossicle.
JACOBIAN ELLIPTIC FUNCTIONS IN SIGNATURE FOUR
Authors: ROBINSON P. L. 
Published: June 2023

AbstractThe signature four elliptic theory of Ramanujan is provided with a counterpart to the Jacobian modular sine; this counterpart yields natural direct proofs of several hypergeometric identities recorded by Ramanujan, bypassing the signature four transfer principle of Berndt et al. [‘Ramanujan’s theories of elliptic functions to alternative bases’, Trans. Amer. Math. Soc.347 (1995), 4163–4244].
Value of surveillance ultrasound following hemithyroidectomy
Authors: O'Brien Owen , Hilmi Omar , Wright Sylvia , McArthur Claire 
Published: June 2023

AbstractBackgroundThere is limited evidence or agreement on the benefit, duration and frequency of post-operative surveillance neck ultrasound in patients with differentiated thyroid cancer treated with hemithyroidectomy alone. This study's primary aim was to assess the benefit of neck ultrasound in this situation, with a secondary aim to assess the detection of malignancy in the contralateral lobe in patients undergoing completion surgery.MethodsA retrospective observational study was conducted involving patients who had differentiated thyroid cancer found at diagnostic hemithyroidectomy between 1 December 2013 and 31 December 2016.ResultsOf 105 patients, 74 underwent completion thyroidectomy. Thirty-five per cent of these patients had malignancy identified in the contralateral lobe, the majority were unsuspected sonographically. Of 31 hemithyroidectomy patients, 1 had a nodule classified as ‘U3’ (indeterminate) at the first ultrasound surveillance, ultimately identified as incidental papillary microcarcinomas on completion thyroidectomy. There was no other disease recurrence or malignancy at a median of 3.8 years’ follow up.ConclusionThe findings indicate a limited role for ultrasound follow up of patients with differentiated thyroid cancer treated with hemithyroidectomy alone.
The Politics of Libel: Thomas Erskine, Freedom of the Press, and Transatlantic Legal Culture, c. 1780–1830
Authors: Phillips Nicola 
Published: June 2023

AbstractThis article analyzes how the multidirectional movement of legal and popular printed texts, newspapers, letters, and citizens contributed to the political and legal influence of individual lawyers across the Atlantic. It is based on a case study of leading common law barrister and Whig MP Thomas Erskine (1750–1823). It examines the dissemination of Erskine's legal and political arguments, and other publications in support of freedom of the press and the constitutional importance of trial by jury in libel trials. Erskine's Country Whig politics, key role in the passage of the 1792 Libel Act, and support for American independence were admired by American lawyers, diplomats, and politicians. His disinterested public service as an advocate meant he personified the ideal of a patriot lawyer that underpinned the classical republican model of law, citizenship, and politics on both sides of the Atlantic. Erskine's powerful, often emotive forensic rhetoric was equally admired as part of a shared transatlantic legal culture, linking law, politics and literature. The speeches were reprinted and widely circulated in edited collections, texts on oratory, trial reports, newspapers, and periodicals; key arguments were also referenced in legal treatises on libel. Hence, parts of his most significant speeches in English libel trials came to be regarded as “usable” legal texts studied by students and re-cited by American defense lawyers in court.
Three Gorges Dam Operations Affect the Carbon Dioxide Budget of a Large Downstream Connected Lake
Authors: Zhao Xiaosong , Fan Xingwang , Griffis Timothy J. , Xiao Ke , Li Xiang , Liu Yuanbo , Lai Xijun , Wan Rongrong , Li Tingting 
Published: June 2023

AbstractThe effects of dams on carbon dioxide (CO2) fluxes in downstream lakes remain elusive. Here we combined eddy covariance observations and random forest models to examine multi‐decadal variations in CO2 fluxes in the Poyang Lake, the largest freshwater lake in China, and quantified the contribution of the Three Gorges Dam (TGD), the world's largest hydraulic project. We found the lake fluctuated between CO2 source and sink in 1961–2016, and tended to be CO2 sink in the post‐TGD period (2003–2016) when vegetation expanded early and spatially due to declining water level. TGD can explain approximately 6% of the total differences in annual CO2 fluxes, with major contributions in the impoundment period (up to 22% in middle September to October). The results show a positive side of operational major hydraulic projects on lake carbon sink, and probably caution the negative side of carbon release after dam removal.
Categorization of High‐Wind Events and Their Contribution to the Seasonal Breakdown of Stratification on the Southern New England Shelf
Authors: Taenzer Lukas L. , Gawarkiewicz Glen , Plueddemann Albert 
Published: June 2023

AbstractHigh‐wind events predominantly cause the rapid breakdown of seasonal stratification on the continental shelf by the end of October. In particular the timing of events leads to considerable interannual variability in the stratification breakdown with a standard deviation of 15 days. Although previous studies have shown how coastal stratification depends on local wind‐forcing characteristics, the locally observed ocean forcing has not yet been linked to regional atmospheric weather patterns that determine the local wind characteristics. Establishing such a connection is a necessary first step toward examining how an altered atmospheric forcing due to climate change affects coastal ocean conditions. Here, we propose a categorization scheme for high‐wind events that links atmospheric forcing patterns with changes in stratification. We apply the scheme to the Southern New England shelf utilizing observations from the Ocean Observatories Initiative Coastal Pioneer Array (2015–2022). Impactful wind forcing patterns occur predominantly during early fall, have strong downwelling‐favorable winds, and are primarily of two types: (a) Cyclonic storms that propagate south of the continental shelf causing anticyclonically rotating winds, and (b) persistent large‐scale high‐pressure systems over East Canada causing steady north‐easterly winds. These patterns are associated with opposite temperature and salinity contributions to destratification, implying differences in the dominant processes driving ocean mixing based on a high‐wind pattern's overall strength and wind direction steadiness. The high‐wind event categorization scheme allows a transition from solely focusing on local wind forcing to considering realistic atmospheric weather patterns when investigating their impact on stratification in the coastal ocean.
High-performance flexible organic field effect transistors with print-based nanowires
Authors: Lu Liangkun , Wang Dazhi , Pu Changchang , Cao Yanyan , Li Yikang , Xu Pengfei , Chen Xiangji , Liu Chang , Liang Shiwen , Suo Liujia , Cui Yan , Zhao Zhiyuan , Guo Yunlong , Liang Junsheng , Liu Yunqi 
Published: June 2023

AbstractPolymer nanowire (NW) organic field-effect transistors (OFETs) integrated on highly aligned large-area flexible substrates are candidate structures for the development of high-performance flexible electronics. This work presents a universal technique, coaxial focused electrohydrodynamic jet (CFEJ) printing technology, to fabricate highly aligned 90-nm-diameter polymer arrays. This method allows for the preparation of uniformly shaped and precisely positioned nanowires directly on flexible substrates without transfer, thus ensuring their electrical properties. Using indacenodithiophene-co-benzothiadiazole (IDT-BT) and poly(9,9-dioctylfluorene-co-benzothiadiazole) (F8-BT) as example materials, 5 cm2arrays were prepared with only minute size variations, which is extremely difficult to do using previously reported methods. According to 2D-GIXRD analysis, the molecules inside the nanowires mainly adopted face-on π-stacking crystallite arrangements. This is quite different from the mixed arrangement of thin films. Nanowire-based OFETs exhibited a high average hole mobility of 1.1 cm2V−1s−1and good device uniformity, indicating the applicability of CFEJ printing as a potential batch manufacturing and integration process for high-performance, scalable polymer nanowire-based OFET circuits. This technique can be used to fabricate various polymer arrays, enabling the use of organic polymer semiconductors in large-area, high-performance electronic devices and providing a new path for the fabrication of flexible displays and wearable electronics in the future.
A direct spino-cortical circuit bypassing the thalamus modulates nociception
Authors: Cai Bing , Wu Dan , Xie Hong , Chen Yan , Wang Huadong , Jin Sen , Song Yuran , Li Anan , Huang Shiqi , Wang Sashuang , Lu Yingjin , Bao Lan , Xu Fuqiang , Gong Hui , Li Changlin , Zhang Xu 
Published: June 2023

AbstractNociceptive signals are usually transmitted to layer 4 neurons in somatosensory cortex via the spinothalamic-thalamocortical pathway. The layer 5 corticospinal neurons in sensorimotor cortex are reported to receive the output of neurons in superficial layers; and their descending axons innervate the spinal cord to regulate basic sensorimotor functions. Here, we show that a subset of layer 5 neurons receives spinal inputs through a direct spino-cortical circuit bypassing the thalamus, and thus define these neurons as spino-cortical recipient neurons (SCRNs). Morphological studies revealed that the branches from spinal ascending axons formed a kind of disciform structure with the descending axons from SCRNs in the basilar pontine nucleus (BPN). Electron microscopy and calcium imaging further confirmed that the axon terminals from spinal ascending neurons and SCRNs made functional synaptic contacts in the BPN, linking the ascending sensory pathway to the descending motor control pathway. Furthermore, behavioral tests indicated that the spino-cortical connection in the BPN was involved in nociceptive responses. In vivo calcium imaging showed that SCRNs responded to peripheral noxious stimuli faster than neighboring layer 4 cortical neurons in awake mice. Manipulating activities of SCRNs could modulate nociceptive behaviors. Therefore, this direct spino-cortical circuit represents a noncanonical pathway, allowing a fast sensory-motor transition of the brain in response to noxious stimuli.
Genome-wide association study of preterm birth and gestational age in a Japanese population
Authors: Hasegawa Keita , Kumasaka Natsuhiko , Nakabayashi Kazuhiko , Kamura Hiromi , Maehara Kayoko , Kasuga Yoshifumi , Hata Kenichiro , Tanaka Mamoru 
Published: June 2023

AbstractPreterm birth (PTB), defined as the birth of a baby at <37 weeks of gestation, is known to be the main cause of neonatal morbidity and mortality. Here, we report genetic associations between preterm birth and gestational age in a Japanese population. We conducted a genome-wide association study (GWAS) of 384 cases who delivered prematurely and 644 controls and considered gestational age as a quantitative trait in 1028 Japanese women. Unfortunately, we were unable to identify any significant variants associated with PTB or gestational age using the current sample. We also examined genetic associations previously reported in European populations and identified no associations, even with the genome-wide subthreshold (p value < 10–6). This data report aims to provide summary statistics of current GWASs on PTB in a Japanese population for future meta-analyses of genetics and PTB with larger sample sizes.
Partial convergence of the human vaginal and rectal maternal microbiota in late gestation and early post-partum
Authors: Shin Hakdong , Martinez Keith A. , Henderson Nora , Jay Melanie , Schweizer William , Bogaert Debby , Park Gwoncheol , Bokulich Nicholas A. , Blaser Martin J. , Dominguez-Bello Maria Gloria 
Published: June 2023

AbstractThe human vaginal and fecal microbiota change during pregnancy. Because of the proximity of these perineal sites and the evolutionarily conserved maternal-to-neonatal transmission of the microbiota, we hypothesized that the microbiota of these two sites (rectal and vaginal) converge during the last gestational trimester as part of the preparation for parturition. To test this hypothesis, we analyzed 16S rRNA sequences from vaginal introitus and rectal samples in 41 women at gestational ages 6 and 8 months, and at 2 months post-partum. The results show that the human vaginal and rectal bacterial microbiota converged during the last gestational trimester and into the 2nd month after birth, with a significant decrease in Lactobacillus species in both sites, as alpha diversity progressively increased in the vagina and decreased in the rectum. The microbiota convergence of the maternal vaginal-anal sites perinatally might hold significance for the inter-generational transmission of the maternal microbiota.
On-chip parallel processing of quantum frequency comb
Authors: Zhang Liang , Cui Chaohan , Yan Jianchang , Guo Yanan , Wang Junxi , Fan Linran 
Published: June 2023

AbstractThe frequency degree of freedom of optical photons has been recently explored for efficient quantum information processing. Significant reduction in hardware resources and enhancement of quantum functions can be expected by leveraging the large number of frequency modes. Here, we develope an integrated photonic platform for the generation and parallel processing of quantum frequency combs (QFCs). Cavity-enhanced parametric down-conversion with Sagnac configuration is implemented to generate QFCs with identical spectral distributions. On-chip quantum interference of different frequency modes is simultaneously realized with the same photonic circuit. High interference visibility is maintained across all frequency modes with the identical circuit setting. This enables the on-chip reconfiguration of QFCs. By deterministically separating QFCs without spectral filtering, we further demonstrate high-dimensional Hong-Ou-Mandel effect. Our work provides the critical step for the efficient implementation of quantum information processing with integrated photonics using the frequency degree of freedom.