bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid nanofiller reinforcement in thermoset and biothermoset applications: A review
Authors: Zulkefli Nur Aliaa , Mustapha Rohani , Jusoh Suriani Mat , Ruzaidi Ghazali Che Mohd , Awang Mohamad , Norrrahim Mohd Nor Faiz , Ilyas Rushdan Ahmad 
Published: February 2023

Abstract
Thermoset and biothermoset applications have been advancing tremendously in recent years due to their easy processing, versatility, and exceptional mechanical and thermal properties. Biothermoset is a type of thermoset that is produced using biological resources, either in portions by blending with the conventional resin, or completely. Various research has been employed to accommodate their high and rapidly growing demands and broaden their functions and implementation in numerous fields. One of these attempts is the reinforcement of nanofillers. Nanofillers such as nanoclay, graphene nanoplatelets, carbon nanotubes, nanodiamond, etc., possess diverse and outstanding properties and are also easily accessible. Recently, there has been a developing trend of hybridizing two or more types of nanofillers as a hybrid reinforcement system to address the limitations of single-filler reinforcement systems and to establish better-supporting properties of the nanocomposites. In this review, we discussed the use of hybrid nanofillers in different thermoset and biothermoset applications. Emphasis is given to the types of hybrids, their interactions with each other and the host polymer, and the effects of their contents and ratios. Limitations from the previous works are also discussed and the future undertaking of research on hybrid nanofillers is also proposed.
Study on the flame retardancy of carrageenan fiber papers
Authors: Zhai Hongjie , Qiao Cuixia , Geng Cunzhen , Xia Yanzhi , Zhao Gang , Xue Zhixin 
Published: February 2023

Abstract
Carrageenan fibers crosslinked with trivalent metal ions (Al3+ or Fe3+) were prepared into carrageenan fiber paper (Al/CAP, Fe/CAP) by the Rapid Kothen method, and their flame-retardant mechanism and flame retardancy were studied through LOI, VF, SEM, CONE, and TGA testing. The results showed that Al/CAP exhibited good flame retardancy and thermal stability, and its LOI value reached 52%. Meanwhile, the afterflame time and afterglow time of Al/CAP were 0 and 1 s, respectively, which indicated that it was not ignited and almost had no smoldering phenomenon. The flame-retardant performance of Fe/CAP is inferior to that of Al/CAP, with LOI of 32, but the total smoke emission (TSP) of Fe/CAP is lower in cone calorimetry test. Thus, CAPs (especially Al/CAP) can be widely used in the flame-retardant paper industry, due to their flame retardancy and environmental protection.
French Predicate Anaphora, Comparatives, and Ellipsis
Authors: Authier J.-Marc 
Published: February 2023

AbstractWhile French does not display the kind of VP-ellipsis found in languages like English, it effects verbal anaphora by means of two constructions that have received relatively little attention in the literature. Both of these combine the generic ‘action verb’faire‘do’ with what appears to be a pronoun. The first one, which I callle-faireanaphora (LFA), uses the cliticle, whereas the second one, which I callfaire-çaanaphora (FCA), brings into play the strong pronounça‘it/that’. Taking such pronouns to be substitutive pro-forms devoid of inner structure cannot, however, explain why LFA, but not FCA, can appear in the standard of a comparative, a property that distinguishes English VP-ellipsis from VP-pro-forms likedo it/that/so, which behave like FCA. On the other hand, LFA, unlike English VP-ellipsis, does not allowwh-extraction from a VP-internal position outside the realm of comparatives, which leads to a paradox left unresolved in the literature. In this article, I argue that LFA involves ellipsis of a wholevP phase. Specifically, I argue thatfairein LFA, but not in FCA, is a (semi)auxiliary verb that takes avP complement and bears an E-feature lexicalized by the cliticle. I show that this correctly predicts that A-movement out of the ellipsis site is possible and that A-bar movement of a degreewh-phrase out ofvP in comparatives is made possible by the fact that French licenses Quantification at a Distance, a grammatical operation that allows degree quantifiers to escapevP before the next phasal head (C) is merged and triggers ellipsis. Otherwh-quantifiers that do not benefit from the Quantification at a Distance option are then expected to not be able to escapevP prior to ellipsis, hence run-of-the-millwh-extraction out of VP is correctly predicted to be incompatible with LFA. I then turn to what appears to be a related anaphoric phenomenon, which consists of the predicational copulaêtre‘be’ and the cliticle, which I calll’êtreanaphora (LEA), and show that it too is an instance of ellipsis in that it allows the full range of extraction phenomena out of the missing constituent introduced by the copula. I assume that in those cases in which the copula takes a small clause, it participates in an asymmetric structure where it lexicalizes Pred, a head that mediates between subject and predicate. In those cases in which the copula introduces a passivized VP, on the other hand, I assume that it lexicalizesv, an assumption in line with theories that posit multiple instantiations of predicate mediators (so-called ‘flavors ofv’). In both cases, the copula in LEA heads a phase, bears an E-feature lexicalized byle, and is argued to license ellipsis of its phasal complement. Thus, elements are allowed to escape ellipsis by moving to the edge of the phase headed by the copula, and this correctly predicts that LEA permits a wider range of extractions out of the ellipsis site than LFA does.
Does poor sleep quality lead to increased low back pain the following day?
Authors: O’Hagan Edel T. , Cashin Aidan G. , Hübscher Markus , Mohammad alsaadi Saad , Gustin Sylvia , McAuley James H. 
Published: February 2023

Abstract

Objectives
This study explored the relationship between sleep quality and next-day pain intensity for people with low back pain and investigated whether there was any evidence that this relationship was causal.

Methods
We conducted a secondary analysis of an observational study that investigated sleep quality in people with low back pain. People with low back pain were recruited from primary care and the community. Sleep quality was measured with subjective (self-report) and objective (polysomnography (PSG)) measures. PSG analysis classifies sleep into stages, of which slow-wave sleep (SWS) is thought to have a key role in maintaining or increasing pain intensity. We drew directed acyclic graphs to identify possible confounders of the relationship between both measures of sleep quality, and pain intensity. We constructed two linear regression models to explore the effect of subjective and objective sleep quality on next-day pain intensity before and after confounder adjustment.

Results
Thirty-nine participants were included in the study. For participants with low back pain, self-reported better quality sleep β=−0.38 (95% CI −0.63 to −0.13), or spending a greater proportion of time in SWS β=−0.12 (95% CI −0.22 to −0.02) was associated with lower next day pain intensity. After confounder adjustment, the effect reduced and was no longer significant for either self-reported β=−0.18 (95% CI −0.46 to 0.10), or SWS β=−0.08 (95% CI −0.18 to 0.03).

Conclusions
Sleep quality, whether measured by self-report or proportion of time in SWS, was associated with next day pain intensity for people with low back pain. However, this relationship is likely to be confounded and therefore not likely to be causal.
Cell sorters see things more clearly now
Authors: Schraivogel Daniel , Steinmetz Lars M 
Published: February 2023

Microscopy and fluorescence‐activated cell sorting (FACS) are two of the most important tools for single‐cell phenotyping in basic and biomedical research. Microscopy provides high‐resolution snapshots of cell morphology and the inner workings of cells, while FACS isolates thousands of cells per second using simple parameters, such as the intensity of fluorescent protein labels. Recent technologies are now combining both methods to enable the fast isolation of cells with microscopic phenotypes of interest, thereby bridging a long‐standing gap in the life sciences. In this Commentary, we discuss the technical advancements made by image‐enabled cell sorting and highlight novel experimental strategies in functional genomics and single‐cell research.
Evaluating the performance of alkali activated concrete with fly ash, lime and GGBS
Authors: Banchhor Sonal , Murmu Meena , Deo Shirish V 
Published: February 2023

AbstractAlkali Activated Concrete (AAC) is a moderately new form of concrete that has gotten a lot of interest in recent decades owing to its environmental advantages and features. However, further research into the effects of various proportions of fly ash, ground granulated blast furnace slag (GGBS), and lime on the characteristics of calcium-based AAC is still needed. This work aims to provide detailed information about the characteristics of AAC with various concentrations of fly ash, GGBS, and lime in order to produce the best combinations for engineering applications. The alkali activators in this investigation are sodium hydroxide and calcium silicate. All concrete mixes are examined for workability, strength, and durability for knowing the impact of fly ash, GGBS, and lime on AAC performance. The results specify that the increase in dosage of GGBBS diminishes the workability. The accumulation of only lime and GGBS shows optimum strength and durability results. In this study further regression analysis has been carried out for predicting the strength of the AAC. The regression equation was developed using the response surface approach for reliably predicting experimental outcomes with an acceptable margin of error.
The evaluation of breast biopsy results before and after the inception of COVID-19 pandemic: Single center retrospective study
Authors: ULU ÖZTÜRK Funda , TEZCAN Şehnaz 
Published: February 2023

Aim: This study aimed to evaluate breast biopsy procedures performed in radiology unit before and after COVID-19 pandemic initiation, and compare breast cancer diagnosis.
Material and Methods: Breast biopsies performed two years before and after March 2020 were retrospectively analyzed. Patient demographics, referral reason (screening/diagnostic), biopsy type and region, tumor size, BI-RADS category and pathology were evaluated. Statistical analysis was made using chi-square test, independent samples t-test and Mann-Whitney U test.
Results: Among 903 biopsies, the mean age was 51 (range 15 to 88 years). Biopsy volume decreased in the early six months of the pandemic, but accelerated soon after, with numbers even more than the pre-pandemic era. Screening intention on patient referral decreased significantly in the pandemic period, where diagnostic purposes arised (p
A eternidade de Wiñaypacha como imagem do pensamento andino
Authors: Caballero Indira Nahomi Viana 
Published: February 2023

Recentemente estreou Wiñaypacha (título em espanhol Eternidad), o primeiro filme peruano longa-metragem integralmente falado em aimará, alcançando imenso sucesso não só nos cinemas do Peru como internacionalmente. O filme dirigido por Óscar Catacora, jovem cineasta peruano de origem aimará, é uma obra-prima tanto por suas qualidades estéticas quanto narrativas. O objetivo deste artigo é mostrar como fotografia e roteiro, também assinados pelo diretor, têm um forte caráter poético e potente enquanto recursos reveladores do pensamento andino, sendo a ideia de Eternidade central nesse sentido. Por fim, trata-se de destacar o protagonismo que os povos andinos alcançam com o sucesso de Wiñaypacha em lugares onde há muito tempo são/estão presentes, porém, vistos predominantemente como coadjuvantes.
Devoradores de deuses
Authors: Macedo Rafael Gonzaga de 
Published: February 2023

Partindo de uma fotografia de uma máscara elmo iorubá presente na obra Negerplastik de Carl Einstein, o artigo procura demonstrar que, ao contrário do que possa parecer à primeira vista, nenhuma fotografia é transparente e que seus pressupostos visuais estão ancorados na experiência do olhar imperial ocidental sobre o outro. Trata-se de explorar as implicações de uma postura que considera a fotografia não meramente como uma ferramenta para a divulgação das artes ditas primitivas, mas como vetor de um devir maquínico dessas artes, devorando e produzindo imagens que expressam uma sensibilidade específica e imperial com sua historicidade e seus dilemas.
A systematic review of economic evaluations of supervised injection and consumption facilities for people who use drugs: A study protocol
Authors: Jozaghi Ehsan 
Published: February 2023

Abstract
Background:
There are now more than 100 supervised injection facilities (SIFs) operating in numerous jurisdictions, including Australia, Canada and Western Europe. However, despite the increasing prevalence of people who use or abuse illegal drugs, including those who inject drugs, there are currently no operating SIFs in Africa, Asia, Central and South America and Eastern Europe. With the exception of Canada in North America, no sanctioned facility currently operates in the United Mexican States or the United States of America. This is the first study to systematically synthetizes the overall benefits and cost-effective ratios associated with operating SIFs, hypothetical SIFs, or drug consumption sites in different jurisdictions.
Methods and Analysis:
In this systematic review, through relying on five electronic scientific data bases, the peer-reviewed studies, reports, and theses that have evaluated the cost and benefits of supervised injection or consumption facilities will be identified. Based on the inclusion criteria, all initial articles will be identified and screened via title and abstract. All the articles collected through the initial search will be additionally screened to extract further information and data related to costs, benefits, programs, or services. The final data analysis will include the average cumulative benefits, costs, and ratios associated with operating SIFs.
Discussion:
This review has the potential to provide evidence-based knowledge related to the cost-savings of public health interventions implemented via harm reduction approaches for marginalized populations. However, it is important to emphasize that SIFs are an integral part of health care system for the marginalized populations and their establishments should not be based on health care costs, rather based on human rights.
Systematic review registration: PROPSERO CRD42018100324
Bayesian compositional regression with microbiome features via variational inference
Authors: SCOTT DARREN A. V. , BENAVENTE ERNEST DIEZ , LIBISELLER-EGGER JULIAN , FEDOROV DMITRY , PHELAN JODY , ILINA ELENA , TIKHONOVA POLINA , KUDRYAVTSEV ALEXANDER , GALEEVA JULIA , CLARK TAANE , LEWIN ALEX 
Published: February 2023

Abstract
The microbiome plays a key role in the health of the human body. Interest often lies in finding features of the microbiome, alongside other covariates, which are associated with a phenotype of interest. One important property of microbiome data, which is often overlooked, is its compositionality as it can only provide information about the relative abundance of its constituting components. Typically, these proportions vary by several orders of magnitude in datasets of high dimensions. To address these challenges we develop a Bayesian hierarchical linear log-contrast model which is estimated by mean field Monte-Carlo coordinate ascent variational inference (CAVI-MC) and easily scales to high dimensional data. We use novel priors which account for the large differences in scale and 1 constrained parameter space associated with the compositional covariates. A reversible jump Monte Carlo Markov chain guided by the data through univariate approximations of the variational posterior probability of inclusion, with proposal parameters informed by approximating variational densities via auxiliary parameters, is used to estimate intractable marginal expectations. We demonstrate that our proposed Bayesian method performs favourably against existing frequentist state of the art compositional data analysis methods. We then apply the CAVI-MC to the analysis of real data exploring the relationship of the gut microbiome to body mass index.
MiR-125 family improves the radiosensitivity of head and neck squamous cell carcinoma
Authors: Wang Qi-Wei , Liu Jiang-Tao , Tan Li-Jun , Zhao Jian-Nan , Zhou Xiao-Jie , Yu Tian-Jiao , Sun Ya-Nan 
Published: February 2023

Abstract
Backgroud: MiRNAs can affect the radiosensitization of head and neck squamous cell carcinoma (HNSCC). We aimed to analyze the function of miR-125 family members in HNSCC using The Cancer Genome Atlas (TCGA) and determine their effect on radiation in laryngeal squamous cell cancer (LSCC).
Methods: First, we systematically analyzed the role of the miR-125 family in HNSCC using the TCGA database and found that miR-125a-5p is associated with radiotherapy. We then performed comprehensive enrichment analysis of miR-125a-5p and predicted target genes. Then, we performed transfection, cell proliferation assays, reverse transcription polymerase chain reaction, apoptosis assays, micronucleus tests, and western blotting on hep-2 cells selected with puromycin.
Results: MiR-125 family members exhibited significantly different expression in HNSCC. They were significantly associated with tumor–node–metastasis staging, clinical stages, and histological grades. Radiation therapy had a statistically effect on miR-125 family members, except miR-125a-3p. Moreover, miR-125a-5p was related to overall survival in LSCC. Thus, we predicted 110 target genes and seven hub genes of miR-125a-5p. The proliferation rate of cells transfected with lentivirus vector expressing miR-125a-5p was significantly reduced compared to the other groups. The radiation effect was enhanced in cells transfected with miR-125a-5p. The ratio of apoptotic cells transfected and exposed to X-rays (10 Gy) was distinctly higher than that of the Ad-control group. Western blotting analysis revealed that miR-125a-5p upregulated the apoptotic regulators P53 and rH2AX. Thus, miR-125a-5p may increase radiosensitivity in LSCC via upregulation of pro-apoptotic genes.
Conclusions: MiR-125 family members could be prognostic biomarkers of HNSCC and improve HNSCC sensitivity to radiotherapy by activating P53. Upregulating miR-125a-5p via lentivirus vectors may be a novel strategy to strengthen the effect of radiotherapy on LSCC.
Dynamic Patterns of Gene Expression and Regulatory Variation in the Maize Seed Coat
Authors: Li Juan , Wang Liangfa , Wan Jiong , Dang Kuntai , Lin Yuan , Meng Shujun , Qiu Xiaoqian , Wang Qiyue , Zhao Jiawen , Mu Liqin , Luo Hongbing , Ding Dong , Chen Zehui , Tang Jihua 
Published: February 2023

Abstract
Background
Seed size is an important factor contributing to maize yield, but its molecular mechanism remains unclear. The seed coat, which serves as one of the three components of the maize grain, determines seed size to a certain extent. The seed coat also shares the maternal genotype and is an ideal material for studying heterosis.
Results
In this study, the self-pollinated seeds of the maize hybrid Yudan888 and its parental lines were continuously collected from 0 day after pollination (DAP) to 15 DAP for phenotyping, cytological observation and RNA-seq. The phenotypic data showed that 3 DAP and 8 DAP are the best time points to study maize seed coat heterosis. Cytological observations indicated that maize seed coat heterosis might be the result of the coordination between cell number and cell size. Furthermore, the RNA-seq results showed that the nonadditive genes changed significantly between 3 DAP and 8 DAP. However, the number of genes expressed additively was not significantly different. Our findings suggest that seed coat heterosis in hybrid is the result of nonadditive expression caused by dynamic changes in genes at different time points during seed expansion and seed coat development. Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment indicated that genes related to DNA replication, cell cycle regulation, circadian rhythms and metabolite accumulation contributed significantly to hybrid seed coat heterosis.
Conclusion
Maize seed coat phenotyping allowed us to infer that 3 DAP and 8 DAP are important time points in the study of seed coat heterosis. Our findings provide evidence for genes involved in DNA replication, cell cycle regulation, circadian rhythms and metabolite accumulation in hybrid with high or low parental expression as major contributors to hybrid seed coat heterosis.
Sliding mode controller with fuzzy supervisor for MPPT of Photovoltaic Pumping system
Authors: Hamdi Taleb , Elleuch Khaled , ABID Hafedh , Toumi Ahmed 
Published: February 2023

Abstract
This paper focuses on a photovoltaic system for pumping water since the use of photovoltaic energy has grown quickly due to its direct obtainability without pollution or noise. This paper proposes a new MPPT controller based on Takagi-Sugeno type fuzzy supervisors and a sliding mode controller. The first generate the maximum power point current under varying climatic condition whereas, the second allows tracking the reference signal produced by the fuzzy supervisor. The system includes a photovoltaic (PV) generator followed by a DC-DC Converter, DC bus, an AC/DC inverter which is connected to the induction motor. This later is coupled to a centrifuge pump. The induction motor is driven based on field oriented control strategy. The Takagi-Sugeno (T-S) type fuzzy supervisors predicts, depending on the variations of climatic variables such as irradiation and temperature, the optimum operating point for the photovoltaic source. The simulation results show the effectiveness of the proposed approach in transient and stationary regimes for different values ​​of climatic variables.
Association of the Pretreatment Lung Immune Prognostic Index with Immune Checkpoint Inhibitor Outcomes in Patients with Advanced Hepatocellular carcinoma
Authors: Sun Tao , Guo Yusheng , Sun Bo , Chen Lei , Ren Yanqiao , Zhu Licheng , Zhang Lijie , Liu Yiming , Zheng Chuansheng 
Published: February 2023

Abstract
Objective
To evaluate whether the pretreatment Lung Immune Prognostic Index (LIPI) is associated with outcomes in advanced hepatocellular carcinoma (HCC) patients under ICI.
Methods
A two-center retrospective study of patients with HCC treated with immune checkpoint inhibitors (ICIs) between January 2018 and January 2021 was performed. The patients were stratified into three groups (good LIPI, intermediate LIPI, and poor LIPI) according to pretreatment LIPI based on dNLR (neutrophil count/ [white blood cell count - neutrophil count]) greater than 3 and LDH greater than LDH normal value. The primary endpoints were overall survival (OS) and progression-free survival (PFS). The second endpoints were disease control rate (DCR) and objective response rate (ORR).
Results
In the pooled cohort (n=224), 80 (35.7%) had a good LIPI (zero factor), 91 (40.6%) had intermediate LIPI (one factor), and 53 (23.7%) had poor LIPI (two factors). The median follow-up was 25.1 months. Median OS was 16.8 months, 12.5 months, and 9.5 months for the good, intermediate, and poor LIPI groups, respectively (P < 0.0001). Median PFS was 11.8 months, 7.8 months, and 4.0 months for the good, intermediate, and poor LIPI groups, respectively (P<0.0001) The intermediate LIPI and poor LIPI were independently associated with shorter OS, PFS，and lower ORR, DCR (P＜0.05).
Conclusion
Pretreatment LIPI was correlated with worse outcomes for ICIs suggesting that LIPI could be promising biomarker for advanced HCC patients under ICIs.