bluuebunny/crossref_metadata_2025_split huggingface dataset:
At home in my enemy's house: Israeli activists negotiating ethical values through ritualized Palestinian hospitality
Authors: Mautner Ori 
Published: September 2023

AbstractEngaged Dharma Israel (EDI) activists resist their state's occupation of West Bank Palestinians by offering them solidarity and support. Whereas most Israelis consider such Palestinians’ houses unsafe, EDI participants “feel at home” when acting as polite guests there, experiencing the hospitality of their politically subordinate counterparts as poignant. Such activists value intimacy—crossing boundaries between self and other on both personal and national levels—which they substantially realize during their visits. However, they also seek to promote Israelis’ and Palestinians’ mutual autonomy, or nonintervention in each other's personal and communal affairs, an often‐competing value that the visits likewise help effectuate. These capacities of hospitality result from its ritualized nature—namely, its tendency to follow conventional scripts that do not require certain inner states (e.g., sincerity). Hospitality can therefore be usefully approached as a ritualized arena that enables people to promote multiple values, or culturally valorized ideals, including ones frequently found in tension. This ability of hospitality to work out and negotiate participants’ plural ethical commitments is embedded in the power dynamics and political inequalities that normally characterize hospitality events.
Peyronie's disease response to intralesional collagenase clostridium histolyticum therapy is independent of baseline testosterone
Authors: Schneider Douglas , O'Leary Mitchell , Amini Eliad , Miller Jake , Hassas Nick , Nguyen Jeanie , Hammad Muhammed A. Moukhtar , Barham David , Yafi Faysal A. 
Published: September 2023

AbstractBackgroundTestosterone plays an important role in collagen metabolism, transforming growth factor‐β1 expression, and wound healing, which are all critical factors in pathogenesis of Peyronie's disease. Some clinical studies have suggested an association between Peyronie's disease and hypogonadism.ObjectiveWe sought to investigate whether baseline total testosterone levels influence response to intralesional collagenase clostridium histolyticum in Peyronie's disease.MethodsA retrospective review of patients receiving collagenase clostridium histolyticum injections with available total testosterone levels within 1 year of initial injection was conducted at a single institution. Baseline demographics, hypogonadal status, total testosterone, number of collagenase clostridium histolyticum cycles, and pre‐ and post‐treatment degrees of curvature were collected. Hypogonadism was defined as total testosterone <300 ng/dL.Results and discussionThirty‐six men were included with mean age of 58.2 years (SD 10.4) and mean body mass index 26.8 (SD 3.2). The mean total testosterone was 459.2 ng/dL (SD 144.0), and four (11.1%) were hypogonadal. Mean pre‐treatment curvature was 47.6°, and mean post‐treatment curvature was 27.8°, with mean improvement of 19.9° (40.1%). Hypogonadal status was not significantly associated with more severe curvature, 46.4° among hypogonadal men as to 57.5° among eugonadal men (p = 0.32). On linear regression analysis, total testosterone did not significantly predict improvement in degrees (β = –0.02; R2 = 0.06; p = 0.14) or percent (β = 0.0; R2 = 0.05; p = 0.18). Improvement in neither degrees nor percent differed significantly by hypogonadal status (p = 0.41 and 0.82, respectively). The cycle number did significantly predict greater improvement in curvature on both univariate and multivariate analyses (β = 5.7; R2 = 0.34; p < 0.01).ConclusionNeither total testosterone nor hypogonadism is associated with a degree of improvement after collagenase clostridium histolyticum treatment.
Communication aimed at engendering trustworthiness: An analysis of CSR messages on Twitter
Authors: Zarzycka Ewelina , Krasodomska Joanna , Dobija Dorota , Grabowski Wojciech , Jemielniak Dariusz 
Published: September 2023

AbstractA growing body of research is exploring corporate communication in relation to corporate social responsibility (CSR) activities on social media (SM). Nonetheless, while these studies have shown that SM communication may be an effective tool for reaching and engaging various stakeholders, how the design of corporate CSR communication engenders trustworthiness has yet to be examined. To address this gap, we suggest that SM communication may include important signals related to trust; thus, we investigate whether companies use sources of trustworthiness (reputation, performance, and appearance) while communicating with stakeholders and the response of the latter to such communication. Our empirical analysis is based on a database containing over 66,000 CSR‐related messages from eight companies focusing on communication extracted from Twitter. These data are coded according to three sources of trustworthiness and two dimensions of CSR communication (social and environmental). Our findings indicate that all three attributes of trustworthiness are used by companies in their CSR social media communication. We also document how corporate efforts to use CSR communication that engenders trustworthiness influence stakeholder engagement. Our study therefore contributes to the literature on trust in relation to CSR by illustrating the importance of signaling that includes different sources of trustworthiness or their combination in corporate communication. By analyzing how the various trust attributes included in CSR communication affect SM reactions, we also identify which attributes lead to greater stakeholder engagement overall, particularly for the two analyzed dimensions of CSR communication.
HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression
Authors: Yang Yang , Zhang Minghui , Zhao Yaxuan , Deng Tingzhi , Zhou Xiang , Qian Hanxu , Wang Mengxuan , Zhang Chuanchuan , Huo Zhengjin , Mao Zijun , Shao Zhufeng , Liu Mengxue , Yang Chunhua , Lin Chunhua , Xu Fuyi , Tian Geng , Zhang Yin 
Published: September 2023

AbstractAmplification of amino acids synthesis is reported to promote tumorigenesis. The serine/glycine biosynthesis pathway is a reversible conversion of serine and glycine catalyzed by cytoplasmic serine hydroxymethyltransferase (SHMT)1 and mitochondrial SHMT2; however, the role of SHTM1 in renal cell carcinoma (RCC) is still unclear. We found that low SHMT1 expression is correlated with poor survival of RCC patients. The in vitro study showed that overexpression of SHMT1 suppressed RCC proliferation and migration. In the mouse tumor model, SHMT1 significantly retarded RCC tumor growth. Furthermore, by gene network analysis, we found several SHMT1‐related genes, among which homeobox D8 (HOXD8) was identified as the SHMT1 regulator. Knockdown of HOXD8 decreased SHMT1 expression, resulting in faster RCC growth, and rescued the SHMT1 overexpression‐induced cell migration defects. Additionally, ChIP assay found the binding site of HOXD8 to SHMT1 promoter was at the −456~−254 bp region. Taken together, SHMT1 functions as a tumor suppressor in RCC. The transcription factor HOXD8 can promote SHMT1 expression and suppress RCC cell proliferation and migration, which provides new mechanisms of SHMT1 in RCC tumor growth and might be used as a potential therapeutic target candidate for clinical treatment.
Measuring the ratio of true‐positive to false‐positive judgements made by child and family social workers in England: A case vignette study
Authors: Wilkins David , Meindl Melissa 
Published: September 2023

AbstractSocial workers routinely make judgements and decisions as part of their everyday practice. The nature and quality of these can have a significant and long‐lasting impact on the children and families concerned. In this paper, we present an analysis of more than 20 000 judgements (n = 21 193) made by social workers (n = 586) in relation to case vignettes, based on a series of anonymized referrals (n = 12) to social services in England. We do so to ascertain how accurately the social workers were able to predict subsequent actions, events and outcomes, and to calculate the ratio of true positives to false positives at various decision thresholds. We find that the social workers' predictions were more accurate than chance in relation to all but one of the referrals, albeit at the cost of a high rate of false positive errors. We consider these findings in relation to what appears to be a general lowering of the threshold for child protection interventions in England in recent years and in relation to who suffers the injustice of false positive errors in child and family social work.
Influence of the presence of dental implants on the accuracy and difficulty level of diagnosis of furcation involvement in molars: An in vitro CBCT study
Authors: Xavier Paula N. I. , Vizzotto Mariana B. , Arús Nádia Assein , Tiecher Priscila F. da S. , Gamba Thiago de Oliveira , Fontana Mathias Pante , Beltrão Rodrigo Gomes , da Silveira Heraldo L. D. 
Published: September 2023

AbstractObjectiveThe aim of this study was to investigate the possible interference of image artifacts (IA) generated by dental implants in the evaluation of furcation involvement (FI) in molars.MethodsTomographic scans of first molars (1M) were performed in dry skulls in the absence and presence of titanium (TI) and zirconia (ZI) dental implants. FI grades were simulated in the alveoli of the 1Ms. Diagnostic accuracy of FI and level of difficulty were verified. Chi‐squared test and logistic regression analysis were used.ResultsThere was no difference in the diagnostic accuracy of FI between the arches (p = .117). The highest diagnostic accuracy value for the implant variable was found in the absence of implants (88.3%) and the lowest in the presence of two ZI implants (66.7%). The highest diagnostic accuracy value for FI was observed in grade 0 (G0). There was no significant difference between the arches regarding the evaluators' perception of difficulty (p > .05). Assessments were considered difficult in 12.7% of the TI implants and in 29% of the ZI implants. Regarding the number of dental implants, assessments were considered difficult in 24.4% cases including one implant and 17.4% cases including two implants. The logistic regression model showed a significant p‐value only for one and two ZI implants (p = .0061 and p = .0096, respectively).ConclusionThe presence of dental implants in the region adjacent to the area of investigation of FI decreased the diagnostic accuracy while increasing the perception of difficulty by the examiners, especially in cases with ZI implants.
Impact of atopic dermatitis on occupational contact dermatitis among young people: A retrospective cohort study
Authors: Dietz Jojo B. , Menné Torkil , Meyer Harald W. , Viskum Sven , Flyvholm Mari‐Ann , Ahrensbøll‐Friis Ulrik , John Swen M. , Johansen Jeanne D. 
Published: September 2023

AbstractBackgroundOccupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.ObjectivesTo determine the prevalence of previously diagnosed AD among young workers with recognized OCD and assess its impact on OCD prognosis.MethodsA retrospective cohort study. A questionnaire was sent to 6251 workers with recognized OCD who were under 35 years at notification (response rate: 47%). Of the respondents, 2392 answered a question about previous doctor‐diagnosed AD and were included in the study. Eczema severity, occupational consequences and quality of life were examined using statistical analyses comparing workers with and without previously diagnosed AD.ResultsThe prevalence of previously diagnosed AD was 41.8% (95% CI: 39.8–43.8). Women had a higher AD prevalence, and workers with AD reported OCD at a younger age. Workers with AD reported more frequent and severe eczema symptoms and had a higher risk of OCD negatively affecting job and occupation choices. Health‐related quality of life was more adversely affected in workers with AD.ConclusionsAD significantly impacts severity and has long‐term consequences for young people with OCD. Targeted prevention strategies need to be developed.
DECONSTRUCTING HISTORICIST TIME, OR TIME'S SCRIBE
Authors: Kleinberg Ethan 
Published: September 2023

ABSTRACTThis article investigates the enduring chronopolitics of Historicism. To do so, I work through two dominant understandings of Historicism: the view that “historicism” is a means to account for the historian's own standpoint or historical situation as the place from which they take up and interpret the past, which I call Historicism A, and the separate (though now more popular) understanding of “historicism” that is derived from Karl Popper's The Poverty of Historicism, which I call Historicism B. I am less interested in what draws these varying definitions of Historicism apart and instead investigate a point of intersection in their understanding of time and temporality. Both strains serve politics via a concept of time as a neutral, uniform, and apolitical scale upon which any political or ideological agenda is enacted. Time here serves as the basis for historical explanation, but its neutrality, homogeneity, and extra‐historicality are a trick. I employ Gérard Genette's analytic of the palimpsest, with the help of Nancy Partner, to expose the ways that Historicism allows the past to be rewritten and overwritten to political and ideological ends that the temporal construct conceals. This then enables me to work through the politics of Historicism and ultimately deconstruct Historicist time, demonstrating how the universal or eternal claims of Enlightenment or pre‐Historicist thought are actually maintained in Historicism as the mechanism to advance political and ideological positions under the cloak of neutrality. In what follows, I make the temporal mechanism of Historicism explicit in order to expose the ethical failings that this mechanism conceals.
Professional use of social media platforms by independent dental hygienists in the Netherlands: A quantitative study
Authors: van Capelleveen Marlotte C. , Slot Dagmar Else 
Published: September 2023

AbstractAimThis study examines the prevalence of the professional use of social media platforms by independent DHs in the Netherlands and assesses the associated personal and demographic factors.MethodsIn this exploratory, observational, cross‐sectional study, independent DHs who were members of the Dutch Dental Hygienist Association (Nederlandse Vereniging voor Mondhygiënisten: NVM) were included. Data were collected from the DH practices' websites. Statistics included frequency distributions, percentages, chi‐square tests for the relationship between the parameters, and multiple logistic regression for the associations between social media use and the personal and demographic factors.ResultsA total of 830 independent DHs from 670 different practices were included in the study. Of these DHs, 34.4% had a link to a social media platform on their website. DHs with practices in the west or south of the Netherlands were more likely to use Facebook (p = 0.035 and p = 0.002, respectively) than those in the east or north. The likelihood of DHs with 4 years of training using Facebook was 1.910 greater than those with 2 years of training (p = 0.002). Furthermore, DHs who graduated in Utrecht were more likely to use Instagram (p < 0.001).ConclusionOver a third of the independent DHs in the Netherlands used social media for professional purposes. DHs who trained in Utrecht for 4 years and who had a practice in the west or south of the Netherlands were more likely to use social media for professional purposes.
On the biodiversity of diatom communities in lakes of East China: Geochemical effects dominated after eutrophication
Authors: Zhao Yanjie , Wang Rong , Xu Min , Zhang Enlou 
Published: September 2023

AbstractAimOver the last century, lakes all over the world have experienced significant eutrophication and become more susceptible to critical transitions. This has prompted a growing need to understand how community dynamics shift following ecological perturbations. This study aims to elucidate the present status, spatial patterns and determinants of biological diversity, and how they have changed in response to alterations driven by eutrophication.LocationLakes of East China, mostly in the Yangtze River Basin.TaxaBacillariophyceae (163 species in 33 genres, see taxa names in Appendix S1).MethodsThe environmental conditions of over 60 lakes were assessed based on parameters such as water quality, physical characteristics and biogeochemical constituents. Surface sediment samples and high‐resolution sediment records were collected to quantify the biodiversity of diatom communities, and principal component analysis (PCA) was used to determine the major environmental gradients. Meanwhile, linear regression, canonical correlation analysis and Mantel tests were used to quantify the correlations between variables.ResultsBiodiversity metrics showed no distinct geographic patterns, although areas near large lakes showed comparatively high evenness. Smaller pairwise dissimilarities were observed among hypereutrophic lakes in comparison to lakes with a lower trophic status. The past century has witnessed a decrease in both pairwise dissimilarity and the standard deviation of evenness. A significant statistical association was found between dissimilarity and ionic concentration and composition in the surface sediment of lakes, rather than nutrient levels.Main ConclusionsFollowing regional eutrophication and human disturbance, a significant reduction in biodiversity differentiation was observed in lakes located in East China. Currently, the dominant factor in determining the beta diversity of diatom communities is geochemical conditions rather than nutrient concentrations. Long‐term stress caused by cultural eutrophication may also have altered the dominant determinant of regional biodiversity and diatom community dynamics.
Loss of the parkinsonism‐associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects
Authors: Wang Jingbo , Joseph Sabitha , Vingill Siv , Dere Ekrem , Tatenhorst Lars , Ronnenberg Anja , Lingor Paul , Preisinger Christian , Ehrenreich Hannelore , Schulz Jörg B. , Stegmüller Judith 
Published: September 2023

AbstractMutations in PARK15, which encodes for the F‐box protein FBXO7 have been associated with Parkinsonian Pyramidal syndrome, a rare and complex movement disorder with Parkinsonian symptoms, pyramidal tract signs and juvenile onset. Our previous study showed that systemic loss of Fbxo7 in mice causes motor defects and premature death. We have also demonstrated that FBXO7 has a crucial role in neurons as the specific deletion in tyrosine hydroxylase‐positive or glutamatergic forebrain neurons leads to late‐onset or early‐onset motor dysfunction, respectively. In this study, we examined NEX‐Cre;Fbxo7fl/fl mice, in which Fbxo7 was specifically deleted in glutamatergic projection neurons. The effects of FBXO7 deficiency on striatal integrity were investigated with HPLC and histological analyses. NEX‐Cre;Fbxo7fl/fl mice revealed an increase in striatal dopamine concentrations, changes in the glutamatergic, GABAergic and dopaminergic pathways, astrogliosis and microgliosis and little or no neuronal loss in the striatum. To determine the effects on the integrity of the synapse, we purified synaptic membranes, subjected them to quantitative mass spectrometry analysis and found alterations in the complement system, endocytosis and exocytosis pathways. These neuropathological changes coincide with alterations in spontaneous home cage behavior. Taken together, our findings suggest that FBXO7 is crucial for corticostriatal projections and the synaptic integrity of the striatum, and consequently for proper motor control.image
Real‐world practice of estrogen and progestogen prescriptions in menopausal women in Japan: A descriptive study using a Japanese claims database
Authors: Inayama Yoshihide , Mizuno Kayoko , Egawa Miho , Yamaguchi Ken , Hamanishi Junzo , Takeuchi Masato , Mandai Masaki , Kawakami Koji 
Published: September 2023

AbstractAimThis study aimed to investigate the real‐world clinical practice of estrogen and progestogen prescriptions for menopausal women.MethodsUsing a health care database in Japan, we conducted a cross‐sectional study on estrogen prescriptions and detailed analyses of newly initiated estrogens and concomitant prescriptions of progestogens. Data between January 2005 and December 2021 were analyzed.ResultsIn 2021, the proportion of women aged 45–49 years receiving estrogens was 25.8 [95% confidence interval (CI): 25.3, 26.3] per 1000 women, while it was 6.4 [95% CI: 6.0, 6.7] for those aged ≥60 years. The prescription of estrogens gradually increased in women aged 50–59 years after 2009. In women without a history of hysterectomy, transdermal estradiol was the primary form of estrogens prescribed for ≥180 days, in women aged <60 years. The proportion of transdermal estradiol gradually increased each year, whereas that of oral‐conjugated equine estrogens decreased. Among progestogen, the proportions of dydrogesterone and transdermal norethisterone acetate increased over time, while that of medroxyprogesterone acetate decreased. Approximately 30% of women prescribed estrogens for ≥180 days did not initiate progestogen concurrently. In women undergoing hysterectomy, progestogen was not initiated in >90% of cases, and transdermal estradiol was prescribed in approximately 80% of cases in 2021.ConclusionsThis study reviewed the prescription of estrogens in menopausal women in Japan. A considerable number of women with a uterus are receiving estrogen therapy rather than estrogen‐progestogen therapy (EPT), despite the guidelines recommending the use of EPT in these women.
Growing Institutional Complexity and Field Transition: Towards Constellation Complexity in the German Energy Field
Authors: Bohn Stephan , Gümüsay Ali Aslan 
Published: September 2023

AbstractBy applying a dynamic approach to field‐level institutional complexity, we explore how growing institutional complexity affects fields over time. We examine field transition processes, which are shaped by the number of logics, the nature of their relationships and the shifts in dominance. Focusing on Germany's energy field, our analysis identifies a variety of conflicts that arose among up to seven institutional logics in the context of the German energy transition, i.e., the transition towards a low carbon energy market. The paper makes two theoretical contributions to the institutional complexity and field literature. First, we develop a process model explaining the field‐level consequences of two different types of growing complexity, namely increasing and accelerating complexity. Second, we identify conflicting logic constellations as a distinct form of complexity that we term constellation complexity. We discuss our contributions in light of the literature on institutional logics and fields and show how applying a dynamic perspective to institutional complexity supports scholars in conceptualizing field transition processes.