bluuebunny/crossref_metadata_2025_split huggingface dataset:
Black Cricket, the College at Haringey and the England and Wales Cricket Board
Authors: Collins Michael 
Published: December 2022

AbstractThis article makes a contribution, based on previously unseen archival materials, to debates about the so‐called ‘decline’ of black cricket in England. It discusses the historical context of the development of black cricket in the postwar period and presents a case study of the Haringey Cricket College—1984–1997—a black‐led project in and around the deprived areas of Tottenham, north London, which, during the period of its existence, produced more first class cricketers than many of the most expensive, elite ‘cricket schools’ in England. In so doing, it achieved national and international acclaim. The article goes on to provide detailed evidence regarding the closure of the college, arguing that the college's demise should not be seen simply as part of a wider process of decreasing interest in cricket within England's black communities, but involved active decisions by the cricket establishment not to support the college. The article raises wider questions about when and how it has been possible to be perceived as legitimately black and English in cricketing terms, and how cricket's authorities should respond to these historical problems.
Effects of the affordable care Act's Medicaid expansion on health insurance coverage for individuals in same‐sex couples
Authors: Mann Samuel , Carpenter Christopher S. , Gonzales Gilbert , Harrell Benjamin , Deal Cameron 
Published: December 2022

AbstractObjectiveTo examine whether the Affordable Care Act's (ACA's) Medicaid expansions affected health insurance coverage for individuals in same‐sex couples.Data Sources and Study SettingWe used data on adults aged 18–64 years in same‐sex couples (n = 33,512) from the 2008–2018 American Community Survey (ACS).Study DesignTo estimate the effect of the impact of the state Medicaid expansions under the ACA on health insurance coverage for sexual minorities, we utilize a standard difference‐in‐differences approach to leverage the variation across geography and time in expanding Medicaid.Data CollectionSecondary and publicly available ACS data were obtained from IPUMS at the University of Minnesota.Principal FindingsWe find that Medicaid expansion significantly increased health insurance coverage among low‐income men and women in same‐sex couples by 4.9 (standard error [SE] = 1.75) and 6.5 (SE = 1.96) percentage points, respectively. We find increases in the likelihood of having Medicaid and reductions in private health insurance from an employer or privately purchased insurance. Effects on Medicaid take‐up are consistently larger for low‐income women in same‐sex couples as compared to low‐income men in same‐sex couples.ConclusionsWe provide the first evidence on the relationship between state Medicaid expansions under the ACA and health insurance coverage among sexual minority adults, a group that has been understudied in past research. Our results confirm that sexual minority adults benefitted from the ACA's Medicaid expansions with respect to increased health insurance coverage.
18‐Fluoride fluorodeoxyglucose positron emission tomography is impactful in newly diagnosed pancreatic adenocarcinoma
Authors: Power Jack , Larcos George 
Published: December 2022

AbstractBackgroundAdenocarcinoma of the pancreas has a dismal prognosis. Surgical resection increases survival but is reliant on accurate detection and staging of disease. In overseas studies, 18F‐FDG positron emission tomography (PET) has been shown to have high diagnostic accuracy and staging utility, but local data remain sparse, in part because the technique has hitherto been unfunded via the Medicare benefits schedule. Although Commonwealth funding for rare tumours (including of the pancreas) has been recently approved to commence in late 2022, the proposed item descriptor wording implies that PET should lead to a significant change in management. Accordingly, the aims of this study are to characterize PET findings in newly diagnosed pancreatic adenocarcinoma using standard parameters, such as the SUVmax, and assess the proportion of cases in which PET altered initial management planning.MethodsWe analysed the PET findings of these cancers (presence and degree of metabolic activity in the primary lesion, as well as within malignant nodal and metastatic lesions) and compared the pre‐ and post‐PET management plans of the referring specialists.ResultsOf 51 patients we found that (a) increasing SUVmax of the primary lesion correlated with an increase in disease stage (r‐value = 0.335; P‐value = 0.016), and (b) PET contributed to a significant change in management in 35% of patients.ConclusionIn newly diagnosed pancreatic adenocarcinoma, parameters in PET correlate with disease stage and the overall findings contribute to a significant management change in about 35% of patients.
The capacity of inspection on farm and at the abattoir to predict post‐mortem outcomes in slaughter pigs: A study at animal level
Authors: Teixeira Dayane Lemos , Salazar Laura C. , Larraín Rafael , Boyle Laura A. 
Published: December 2022

AbstractThe aim of this study was to investigate associations between ear, tail, and skin lesions, hernias, bursitis, and rectal prolapses at the abattoir and meat inspection outcomes in slaughter pigs, including carcass condemnations and trimmings, carcass weight, and carcass quality. This was an observational study whereby pigs were managed according to routine practices in a single abattoir. Data were collected from 1816 pigs. The relationship between animal‐based welfare and post‐mortem outcomes was analyzed using generalized mixed models (Proc Glimmix). Our findings showed that tail lesions were associated with entire carcass condemnations and trimmings (P < 0.001), a reduction in carcass weight (P < 0.05), and a potential to impair carcass quality by reducing muscle pH (P < 0.05), especially in carcasses from male pigs (P < 0.05). Additionally, hernias were associated with viscera condemnation (P < 0.05) and a reduction in carcass weight (P < 0.05). Therefore, our findings confirm that ante‐mortem inspection could be useful to predict post‐mortem outcomes in the same pigs, especially in cases of tail lesions and hernia, which might trigger attention of the veterinary inspector in charge of the post‐mortem inspection.
Caring fathers in Europe: Toward universal caregiver families?
Authors: Martínez‐Pastor Juan‐Ignacio , Jurado‐Guerrero Teresa , Fernández‐Lozano Irina , Castellanos‐Serrano Cristina 
Published: December 2022

AbstractIncreasingly, men are challenging the assumption that care is a feminine task and are involving themselves in childcare and the care of dependent adults. However, this does not necessarily have consequences for their work, as they very rarely make costly adaptations in their working lives. In this study, we propose a definition of a man in care (MIC) as a working father who, in order to meet care needs, has adapted his working life in a way that potentially entails a financial penalty. We analyze the prevalence of men in care among men living with children below the age of 15 across the EU‐27 plus Iceland, Norway, Switzerland, and the UK using recent representative data (the European Labour Survey and its 2018 ad hoc module on work‐life balance). We find that although the number of men engaging in costly work adaptations is still very low when compared to their female counterparts, the characteristics of these men can be clearly outlined: they have a non‐manual occupation (managers excluded), they have temporary contracts or are self‐employed, they are partnered to women who hold jobs of 40 or more hours a week and have a high educational attainment, and they work in family‐friendly companies. Also, at the context level, the prevalence of MIC is clearly related to gender equality and values. However, we do not find evidence of any country having reached the universal caregiver model proposed by Nancy Fraser, including those with more advanced gender and welfare regimes.
Impact of COVID‐19 infection and vaccination in pancreatobiliary IgG4‐related disease patients: An international multicenter study
Authors: Tang Raymond S Y , Sattayalertyanyong Onuma , Kuo Yu‐Ting , Park Kenneth H , Anastassiades Constantinos , Ligresti Dario , Hayashi Nobuhiko , Hasan Aws , Kim Tae‐Hyeon , Pausawasdi Nonthalee , Wang Hsiu‐Po , Lo Simon K , Ho Khek‐Yu , Barresi Luca , Traina Mario , Yasuda Ichiro , Savides Thomas J , Koo Chieh‐Sian , Chan Ting Ting , Lam Thomas Y T , Sung Joseph J Y 
Published: December 2022

AbstractBackground and AimDedicated studies evaluating the impact of COVID‐19 on outcomes of pancreatobiliary IgG4 related disease (IgG4‐RD) patients are scarce. Whether COVID‐19 infection or vaccination would trigger IgG4‐RD exacerbation remains unknown.MethodsPancreatobiliary IgG4‐RD patients ≥ 18 years old with active follow‐up since January 2020 from nine referral centers in Asia, Europe, and North America were included in this multicenter retrospective study. Outcome measures include incidence and severity of COVID‐19 infection, IgG4‐RD disease activity and treatment status, interruption of indicated IgG4‐RD treatment. Prospective data on COVID‐19 vaccination status and new COVID‐19 infection during the Omicron outbreak were also retrieved in the Hong Kong cohort.ResultsOf the 124 pancreatobiliary IgG4‐RD patients, 25.0% had active IgG4‐RD, 71.0% were on immunosuppressive therapies and 80.6% had ≥ 1 risk factor for severe COVID. In 2020 (pre‐vaccination period), two patients (1.6%) had COVID‐19 infection (one requiring ICU admission), and 7.2% of patients had interruptions in indicated immunosuppressive treatment for IgG4‐RD. Despite a high vaccination rate (85.0%), COVID‐19 infection rate has increased to 20.0% during Omicron outbreak in the Hong Kong cohort. A trend towards higher COVID‐19 infection rate was noted in the non‐fully vaccinated/unvaccinated group (17.6% vs 33.3%, P = 0.376). No IgG4‐RD exacerbation following COVID‐19 vaccination or infection was observed.ConclusionWhile a low COVID‐19 infection rate with no mortality was observed in pancreatobiliary IgG4‐RD patients in the pre‐vaccination period of COVID‐19, infection rate has increased during the Omicron outbreak despite a high vaccination rate. No IgG4‐RD exacerbation after COVID‐19 infection or vaccination was observed.
Ceruloplasmin‐deficient mice show changes inPTMprofiles of proteins involved in messengerRNAprocessing and neuronal projections and synaptic processes
Authors: Villadsen Birgitte , Thygesen Camilla , Grebing Manuela , Kempf Stefan J. , Sandberg Marie B. , Jensen Pia , Kolstrup Stefanie H. , Nielsen Helle H. , Larsen Martin R. , Finsen Bente 
Published: December 2022

AbstractCeruloplasmin (Cp) is a multicopper oxidase with ferroxidase properties being of importance to the mobilisation and export of iron from cells and its ability to bind copper. In ageing humans, Cp deficiency is known to result in aceruloplasminemia, which among other is characterised by neurological symptoms. To obtain novel information about the functions of Cp in the central nervous system (CNS) we compared the brain proteome in forebrains from asymptomatic 4‐6‐month‐old Cp‐deficient (B6N(Cg)‐Cptm1b(KOMP)Wtsi/J) and wild‐type mice. Of more than 5600 quantified proteins, 23 proteins, were regulated, whereas more than 1200 proteins had regulated post‐translational modifications (PTMs). The genes of the regulated proteins, glycoproteins and phosphoproteins appeared mostly to be located to neurons and oligodendrocyte precursor cells. Cp deficiency especially affected the function of proteins involved in the extension of neuronal projections, synaptic signalling and cellular mRNA processing and affected the expression of proteins involved in neurodegenerative disease and diabetes. Iron concentration and transferrin saturation were reduced in the blood of even younger, 3‐ to 5‐month‐old, Cp‐deficient mice. Iron act as cofactor in many enzymatic processes and reactions. Changes in iron availability and oxidation as consequence of Cp deficiency could therefore affect the synthesis of proteins and lipids. This proteomic characterisation is to our knowledge the first to document the changes taking place in the CNS‐proteome and its phosphorylation and glycosylation state in Cp‐deficient mice.image
A case of cystic lymphangioma arising from the parauterine tissue
Authors: Semba Satoki , Kodama Takashi , Nomura Nana , Sato Yuki , Urabe Satoshi , Hirata Eiji 
Published: December 2022

AbstractA 57‐year‐old woman, gravida 3, para 3, with no complaints visited our hospital for right‐sided adnexal tumor found incidentally in cancer screening. She had no medical history, surgical history, or gynecological disease. Imaging studies showed a 5‐cm lobular cystic tumor on the right side of uterus. We suspected right hydrosalpinx and decided to perform diagnostic laparoscopy. During laparoscopy, the right adnexa was found to be atrophic, and the tumor was located in the broad ligament. The tumor was observed to be a multilocular cyst containing yellow fluid that developed from the right parauterine tissue. The tumor was resected from the surrounding tissue. Histological examination revealed that the multilocular cyst contained a vascular component surrounding the lymphatic endothelium and was decided to be a cystic lymphangioma. The patient was followed up and there was no evidence of recurrence at postoperative 7 months. We experienced a very rare case of lymphangioma arising from the parauterine tissue. The laparoscopic approach can assist with both diagnosis and treatment.
Nurse intervention process for the thoughts and concerns of people with cancer at the end of their life: A structural equation modeling approach
Authors: Tanaka Aiko , Nagata Chizuru , Goto Miyuki , Adachi Keiichiro 
Published: December 2022

AbstractOver the last decade, the importance of Advanced Care Planning has been recognized in Japan. However, it is still difficult for healthcare providers and patients to verbalize how they want to spend the last days of their lives and what unfinished business they have left to accomplish. This study aimed to clarify how nurses intervened to assist patients with cancer at the end of life to express their thoughts and concerns. Twenty‐four nurses were interviewed regarding how they intervened for patients' thoughts and concerns, and data were analyzed qualitatively using a modified grounded theory approach. A 25‐item scale was selected, and the questionnaires, which included the scale, were distributed to nurses in general wards, palliative care units, and home visiting nurse services. A total of 1864 responses were analyzed. Factor analysis and structural equation model analysis were used, and three factors were identified: “assessment and intervention,” “basic care,” and “knowledge and communication,” which led to the formulation of an intervention structure model for uncovering thoughts and concerns. These results indicate the importance of basic care and communication during interventions for patients.
H2O2, NO, and H2S networks during root development and signalling under physiological and challenging environments: Beneficial or toxic?
Authors: Mukherjee Soumya , Corpas Francisco J. 
Published: December 2022

AbstractHydrogen peroxide (H2O2) is a reactive oxygen species (ROS) and a key modulator of the development and architecture of the root system under physiological and adverse environmental conditions. Nitric oxide (NO) and hydrogen sulphide (H2S) also exert myriad functions on plant development and signalling. Accumulating pieces of evidence show that depending upon the dose and mode of applications, NO and H2S can have synergistic or antagonistic actions in mediating H2O2signalling during root development. Thus, H2O2‐NO‐H2S crosstalk might essentially impart tolerance to elude oxidative stress in roots. Growth and proliferation of root apex involve crucial orchestration of NO and H2S‐mediated ROS signalling which also comprise other components including mitogen‐activated protein kinase, cyclins, cyclin‐dependent kinases, respiratory burst oxidase homolog (RBOH), and Ca2+flux. This assessment provides a comprehensive update on the cooperative roles of NO and H2S in modulating H2O2homoeostasis during root development, abiotic stress tolerance, and root‐microbe interaction. Furthermore, it also analyses the scopes of some fascinating future investigations associated with strigolactone and karrikins concerning H2O2‐NO‐H2S crosstalk in plant roots.
Wound healing dynamics, morbidity, and complications of palatal soft‐tissue harvesting
Authors: Tavelli Lorenzo , Barootchi Shayan , Stefanini Martina , Zucchelli Giovanni , Giannobile William V. , Wang Hom‐Lay 
Published: December 2022

AbstractPalatal‐tissue harvesting is a routinely performed procedure in periodontal and peri‐implant plastic surgery. Over the years, several surgical approaches have been attempted with the aim of obtaining autogenous soft‐tissue grafts while minimizing patient morbidity, which is considered the most common drawback of palatal harvesting. At the same time, treatment errors during the procedure may increase not only postoperative discomfort or pain but also the risk of developing other complications, such as injury to the greater palatine artery, prolonged bleeding, wound/flap sloughing, necrosis, infection, and inadequate graft size or quality. This chapter described treatment errors and complications of palatal harvesting techniques, together with approaches for reducing patient morbidity and accelerating donor site wound healing. The role of biologic agents, photobiomodulation therapy, local and systemic factors, and genes implicated in palatal wound healing are also discussed.
Downregulation of Sonic hedgehog signaling induces G2‐arrest in genital warts
Authors: Du Xiangxi , Li Shan , Yang Kun , Cao Yuchun 
Published: December 2022

AbstractBackgroundHuman papillomavirus (HPV) infected keratinocyte dysfunction results in the formation of genital warts, and the specific role of Sonic hedgehog (SHh) signaling in genital warts remains elusive. Thus, this study aimed to identify the correlation between wart formation and SHh signaling.Materials and methodsIn this study, nine male patients with genital warts were recruited, and the expression of SHh and its downstream signal molecules Patched‐1 and GLI family zinc finger 1 (Ptch1 and Gli1) was detected. Moreover, G2‐phase cells in the collected genital warts samples were assessed with normal foreskin samples as a comparison. HPV6/11 were detected via in situ hybridization (ISH), and SHh expression of the corresponding paraffin sections was determined via immunohistochemical staining (IHC). In addition, an in vitro down‐regulated SHh model was constructed by siRNA transfection of the HaCaT cell line, and the cell cycle was detected at 36 h by flow cytometry with propidium iodide staining.ResultsSHh, Ptch1, and Gli1 in warts were significantly downregulated in the condyloma acuminatum (CA) group compared to the normal foreskin group. G2‐phase cells in the middle section of the spinous layer of CA wart tissues were significantly increased. Moreover, the expression of HPV‐DNA was amplified and negatively correlated with SHh activity in CA wart tissues. Lastly, the downregulation of SHh‐induced G2 arrest in vitro.ConclusionsThe downregulation of the SHh signaling promotes HPV replication and the formation of warts by inducing G2/M arrest in the keratinocytes of CA.
Birth order and morbidity and mortality to hospital discharge among inborn very low-birthweight, very preterm twin infants admitted to neonatal intensive care: a retrospective cohort study
Authors: Del Pino Hernández Iris L , García Domínguez María J , Urquía Martí Lourdes , Reyes Suárez Desiderio , Avila-Alvarez Alejandro , García-Muñoz Rodrigo Fermín 
Published: December 2022

ObjectiveTo know the association of birth order with the risk of morbidity and mortality in very low-birthweight (VLBW) twin infants less than 32 weeks’ gestational age (GA).DesignRetrospective cohort study.SettingInfants admitted to the collaborating centres of the Spanish SEN1500 neonatal network.PatientsLiveborn VLBW twin infants, with GA from 23+0weeks to 31+6weeks, without congenital anomalies, admitted from 2011 to 2020. Outborn patients were excluded.Main outcome measuresRespiratory distress syndrome (RDS), patent ductus arteriosus, bronchopulmonary dysplasia (BPD), necrotising enterocolitis, major brain damage (MBD), late-onset neonatal sepsis, severe retinopathy of prematurity, survival and survival without morbidity. Crude and adjusted incidence rate ratios were calculated.ResultsAmong 2111 twin pairs included, the second twin had higher risk (adjusted risk ratio (aRR) of RDS (aRR 1.08, 95% CI 1.03 to 1.12) and need for surfactant (aRR1.10, 95% CI 1.05 to 1.16). No other significant differences were found, neither in survival (aRR 1.01, 95% CI 0.99 to 1.03) nor in survival without BPD (aRR 1.02, 95% CI 0.99 to 1.05), survival without MBD (aRR 1.02, 95% CI 0.99 to 1.06) nor in survival without major morbidity (aRR 0.97, 95% CI 0.92 to 1.03). However, second twins born by caesarean section (C-section) after a vaginally delivered first twin had less overall survival and survival without MBD.ConclusionIn modern perinatology, second twins are still more unstable immediately after birth and require more resuscitation. After admission to the neonatal intensive care unit, they are at increased risk of RDS, but not other conditions, except for second twins delivered by C-section after a first twin delivered vaginally, who have decreased overall survival and survival without major brain injury.
Evaluation of the long-term variability of macular OCT/OCTA and visual field parameters
Authors: Wu Jo-Hsuan , Moghimi Sasan , Nishida Takashi , Walker Evan , Kamalipour Alireza , Li Elizabeth , Mahmoudinezhad Golnoush , Zangwill Linda M , Weinreb Robert N 
Published: December 2022

Background/aimsTo assess the long-term variability of macular optical coherence tomography (OCT)/OCT angiography (OCTA) and visual field (VF) parameters.MethodsHealthy and glaucoma eyes with ≥1-year follow-up were included. 24–2 VF and macular OCT/OCTA parameters, including VF mean deviation (MD), whole-image vessel density (wiVD) and ganglion cell complex thickness (wiGCC) were analysed. Intraclass correlation coefficient (ICC), root mean squared error (RMSE), within-subject test–retest SD (Sw) and test–retest variability were calculated for stable eye cohort (max follow-up=1.5 years). Rates of change and RMSE were evaluated in the extended cohort including all eyes (unlimited follow-up).ResultsFrom a total of 230 eyes (150 participants; age=67.7 years), 86 eyes (37%, 62 participants) were stable. In stable eyes, OCT parameters showed the highest mean (95%) ICC (wiGCC=0.99 (0.99, 0.99)), followed by VF (VF MD=0.91 (0.88, 0.93)) and OCTA (wiVD=0.82 (0.75, 0.87)). RMSE and Sw for VF MD were 0.92 dB and 0.81 dB, respectively, for wiVD were 1.64% and 1.48%, respectively, and for wiGCC, 0.91 µm and 0.78 µm, respectively. The long-term test–rest variability of VF MD, wiVD and wiGCC was 2.2 dB, 4.1% and 2.2 µm, respectively. In the extended cohort (mean follow-up=3.0 years), all parameters had significant rates of change (p<0.001), and compared with the stable cohort, only slightly higher RMSE (VF MD=1.07 dB; wiGCC=2.03 µm; wiVD=2.57%) were found.ConclusionsVF and macular OCT/OCTA, particularly OCT parameters, showed small long-term variability in all eyes, including stable ones, supporting the use of these instruments in glaucoma follow-up. Changes in macular VD and GCC greater than 4%–5% and 2 µm, respectively, indicate possible progression.Trial registration numberNCT00221897.