bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Antimullerian Hormone in the Diagnosis of Poly Cystic Ovarian Syndrom.
Authors: Al-Taee Hanan A. 
Published: June 2023

Background: Polycystic vary syndrome (PCOS) is a common endocrine disorder, affecting up to 10% of women of reproductive age. The cardinal features of PCOS are hyperandrogenism (HA) and oligo-anovulation. Many work teams recently have relate the severity of PCOS with Anti mullerian hormone (AMH) or antral follicle count (AFC). Objective: 1) to confirm if there is an increase of serum AMH in this group of patients with PCOS, 2) to relate the AMH level to the follicle status at ultrasound (U/S) in this group, and 3) to search if AMH or AFC can serve as surrogate for the definition of PCOS.
Patients and methods: Twenty five (control) and another 45 participants (with PCOS) were selected for this study. The control women had a mean age of 32.5 year (yr) and the patients group women had a mean age of 28.4 yr. Blood samples were collected from all participants, anthropometric measurements were calculated, and transvaginal U/S was performed to measure the AFC during the early follicular phase. The blood samples were assayed for AMH, follicle-stimulating hormone (FSH), Luteinizing Hormone (LH) and estradiol (E2) and total testosterone (TT).
Results: Basal serum hormonal levels of LH, AMH and TT as well as AFC were significantly higher in the study group than in controls. While basal serum levels of E2 and FSH show no significant difference between the two groups. Body mass index (BMI) is significantly higher in PCOS patients. Basal serum levels of AMH show significant positive correlation with both AFC and basal serum TT levels.The area under the receiver operating characteristic curve (ROCAUC ) for AMH and AFC show significant sensitive and specificities
Conclusion: serum AMH and AFC appear as a sensitive and specific parameter that would probably help in the diagnosis of PCOS. Both criteria need to be incorporated into the Rotterdam definition for PCOS, and it indicates PCOS only if associated with HA and/or oligo-anovulation.
Calisthenics versus Pilates training on glycemic control and body fat in overweight individuals with type 2 diabetes mellitus
Authors: Kamat Kinjol , Kage Vijay , Sequeira Sherin 
Published: June 2023

BACKGROUND: Physical activity plays an important role in management and preventing complications of type 2 diabetes mellitus (DM). Effectiveness of Pilates on DM showed that there was improvement in glucose control. Presently, resistance training forms are becoming very popular for weight loss and DM. Calisthenics is a relatively new form of resistance exercise training that has been less studied in obese and diabetic individuals. STUDY PURPOSE: To evaluate and compare the effect of Calisthenics and Pilates training approaches on percentage body fat and glycemic control (HbA1C, Post Prandial Blood Glucose (PPBG)) in overweight individuals with type 2 Diabetes mellitus (DM). METHODS: Thirty ( n = 30) over weight individuals with type 2 DM with HbA1C levels >6.5% were recruited for the study. The participants were randomly allocated to calisthenics (CG) and Pilates (PG) study groups who received respective exercise interventions for 12 weeks. The outcome measures were HbA1C, PPBG and percentage body fat assessed at pre and post intervention. RESULTS: Both CG and PG study groups showed statistically significant difference for glycemic control (HbA1C, PPBG) post 12 week intervention. However, significant improvement was noted in CG than PG in terms of HbA1c ( p = 0.03), PPBG ( P = 0.01) and body fat percentage ( p < 0.0001). CONCLUSION: Calisthenics exercise training was more effective than the Pilates training in achieving long term (HbA1c) and post meal (PPBS) glycemic control with significant reduction in body fat percentage in overweight individuals with type 2 DM.
Skin blood flow as an objective measure for lateral elbow tendinopathy
Authors: Sakulsriprasert Prasert , Bunprajun Tipwadee , Soonthonsawat Subkamon 
Published: June 2023

PURPOSE: To investigate the test-retest reliability, side-to-side difference, responsiveness, and concurrent validity of skin blood flow (SkBF) measured by laser Doppler flowmetry (LDF) in individuals with acute or subacute lateral elbow tendinopathy (LET). METHODS: Eighteen individuals with acute or subacute LET were recruited for this study. SkBF was measured over the lateral epicondyle and common extensor origin on both ipsilateral and contralateral sides. The intraclass correlation coefficient (ICC3,1) was used to evaluate test-retest reliability. A paired t-test was used for comparing the side-to-side difference. Responsiveness was reported with a change score, paired t-test, effect size (ES), and standardized response mean (SRM). The concurrent validity of SkBF was investigated by correlating with a visual analog scale (VAS) pain intensity during resisted wrist extension isometric contraction using the Spearman correlation coefficient. RESULTS: Test-retest reliability was good at lateral epicondyle (ICC3,1 = 0.899), and at common extensor origin (ICC3,1 = 0.803). A side-to-side difference was found between the two sides ( p < 0.001). For responsiveness, the change score for SkBF at the lateral epicondyle was – 8.04, and the common extensor origin was – 3.54. The ES and SRM ranged from – 0.71 to – 0.78. Concurrent validity was reported with a strong correlation with pain intensity ( r = – 0.637). DISCUSSION: SkBF is a reliable and responsive variable for investigating the elbows with acute or subacute LET providing clinical information according to its inflammatory responses. However, the concurrent validity can be found only for SkBF at common extensor origin, which correlates with pain during resisted wrist extension isometric contraction.
Assessing lower limb angles from sagittal plane images captured with a smartphone for post-stroke gait
Authors: Kitaji Yu , Sato Haruhiko , Ishida Shinnosuke , Harashima Hiroaki , Miyano Satoshi 
Published: June 2023

BACKGROUND: Clinical gait analysis of sagittal plane lower-limb kinematics using video images is a quantitative tool for clinicians. However, the reliability and validity of limb kinematics after stroke using video images has not been fully investigated. OBJECTIVE: This study aimed to examine the within-session inter-rater reliability and criterion-related validity of lower limb angles measured in sagittal plane images captured using a smartphone for assessing post-stroke gait and to determine which asymmetric parameters are associated with faster gait velocity. METHODS: Thirty-two patients with stroke were included; video images were recorded as they walked at their preferred pace for 1–3 cycles. Lower limb angles (contact, push-off, and excursion angles) and degree of asymmetry were determined based on video images using markers of acromion, greater trochanter, and fifth metatarsal head. Measurement reliability was calculated using the two-way random effects model of intraclass correlation coefficients and minimal detectable change. The criterion validity investigated Pearson’s correlation between lower limb angles and their asymmetry and gait velocity. RESULTS: The lower value of the 95% confidence interval of intraclass correlation coefficients (2.3) of the lower limb was 0.891, and the maximum minimal detectable change was 9.6 degrees. Push-off angle showed a moderate-to-strong correlation with gait velocity, whereas the asymmetry of the push-off angle showed a weak correlation with gait velocity. CONCLUSIONS: Assessing post-stroke gait utilizing video images using a smartphone is feasible. The push-off angle, in particular, may provide insight into the clinical assessment of post-stroke gait.
About some differences in the construction of stage action by a director of drama and musical theaters
Authors: Khorolets Larysa 
Published: June 2023

The purpose of the study is to diagnose the prospects for the implementation of expressive techniques that allow to solve any dramatic problems and reveal the life of the "human spirit" in all its subtlest manifestations, accumulated over the centuries of existence in the works of musical drama. The research is related to the analysis of the adequacy of the modern understanding of the problem and prospects of music to finally take a leading position in the synthetic form of theater, which we call modern musical theater. The research methodology is determined by observational, analytical and historical-logical analysis of the prospects of understanding the need for directorial search for new methods of expression for the dramatic tasks of musical theater, given that in each era and in each country this problem was solved differently. The novelty of the study is to expand the idea of ​​how to generalize from the generalizing properties of music specific stage tasks, and how to make these tasks do not contradict its emotional and figurative structure. How to make the very ability of music to generalize help to deepen and enlarge the emotion that will be born on stage as a result of the right task set for the actor. Conclusions. The method by which a play is solved in a dramatic theater cannot be completely transferred to a musical theater. The prominent, leading position of music in musical theater requires a different approach, a different creative method. Music, which is the art of generalizing experiences, however, does not allow to "make an event" where it is. so to speak, not audible at all. And in this sense, the director of a musical theater dictates more specific conditions: through the events heard in music, to see the series in which they were built by the composer, and to understand exactly the conflict that aroused the imagination of the author.
Key words: musical theater, director of musical theater, musical drama, means of expression, event series, stage action, stage conflict, score, composer-playwright.
Structuring the benchmarks of artistic and creative motivation for creating a stage image of a role by an actor in a drama theatre
Authors: Donchenko Natalia 
Published: June 2023

The purpose of the article. Determination of the structure of the main guidelines of artistic and creative motivation in the process of creating a stage image of a role by an actor in a drama theatre. The research methodology consists of the use of systemic, art history, analytical, structural, and functional methods of researching the main guidelines in organizing the creative process of transforming the performer of the role actor into a certain stage image in accordance with the subject of his creative activity in the theatrical production, which is directly represented by the character of the dramatic work. Research novelty. For the first time, the structuring of the conceptual and categorical basis of guidelines for artistic and creative motivation of professional requirements for creating a stage image by an actor in a drama theatre has been carried out. Conclusions. At present, the fundamental scientific-theoretical method of consistency in building the structuring of the process of an actor's work on a stage image, apart from Stanislavsky's orientation system, has not been developed. For the better or not, is a controversial issue, because the creative search for a more effective and universal basis for acting is taking place in modern creative laboratories of theatre artists. So, the process of inventing new original artistic techniques for a stage play, figurative motivations, and the interpretation of a character in a dramatic form remains an incompletely resolved problem for stage artists.
Key words: theatre, actor, acting, stage image, character, role, character.
Struktur Populasi Katak Batu Berbintik Hitam Staurois guttatus (Ranidae:Amphibia) di Gunung Poteng, Kalimantan Barat
Authors: Anwar Khairul , Junardi Junardi , Riyandi Riyandi 
Published: June 2023

Katak batu berbintik hitam (Staurois guttatus) merupakan spesies endemik Borneo yang dapat ditemukan di Sabah Sarawak (Malaysia), Brunei Darussalam dan Kalimantan (Indonesia). Status konservasi S. guttatus termasuk spesies yang terancam punah menurut International Union for Conservation of Nature (IUCN). S. guttatus dikonfirmasi bahwa di Gunung Poteng tersebut masih belum diketahui. Penelitian ini bertujuan untuk mengetahui struktur populasi S.guttatus di kawasan Gunung Poteng. Sampling menggunakan metode VES (Visual Encounter Survey) dengan line transect sepanjang 500 meter disepanjang riam dan aliran sungai. Pengamatan dilakukan pada malam hari pukul 20.00 - 00.00 WIB. Faktor lingkungan yang diukur meliputi suhu udara, suhu air, kelembaban udara, dan pH air. Hasil penelitian dari tiga waktu sampling diperoleh total 273 individu jantan, 34 individu betina, dan 6 individu juvenil dengan kepadatan rata rata individu jantan yaitu 72 Ind/Ha, 54 Ind/Ha dan 57 Ind/Ha.
The Growth of Bacillus cereus (IHB B 379) Isolates at Different Temperature and Concentration of Mercury Chloride (HgCl2)
Authors: Boni Boni Pasius Wiro , Turnip Masnur , Kurniatuhadi Rikhsan 
Published: June 2023

Bacillus cereus (IHB B 379) has been isolated from the sediments of the illegal gold mining area located in Danau Biru Singkawang, these bacteria have resistant properties by being able to grow on media containing HgCl2 with a concentration of 500 ppm. This study aimed to determine the effect of temperature and concentration of mercuric chloride (HgCl2) on the growth of Bacillus cereus (IHB B 379) and to determine the temperature and concentration of mercuric chloride (HgCl2) on the optimum growth of Bacillus cereus (IHB B 379). The study used a Completely Randomized Factorial Design (CRD) consisting of two treatment factors. The first factor was a different temperature treatment with three levels, namely 320C, 370C, and 420C. The second factor was the treatment of the mercuric chloride (HgCl2) concentration with three levels, namely 0 ppm, 250 ppm, and 500 ppm. The Bacillus cereus (IHB B 379) growth test used the delusional method and the number of colonies was calculated using the Total Plate Count (TPC) method. The results showed that the growth of Bacillus cereus (IHB B 379) was seriously affected by the temperature and concentration of HgCl2 . The best growth pattern of Bacillus cereus (IHB B 379) was occurred at 320C and concentration HgCl2 250 ppm.
Aktivitas Antibakteri Ekstrak Metanol Daun Sengkubak (Pycnarrhena cauliflora) Terhadap Bakteri Eschericia coli dan Staphylococcus aureus
Authors: Inggit Novitasari  , Linda Riza , Kurniatuhadi Rikhsan 
Published: June 2023

Eschericia coli dan Staphylococcus aureus merupakan contoh bakteri penyebab infeksi pada tubuh manusia. Salah satu tanaman yang berpotensi sebagai antibakteri adalah tanaman sengkubak. Sengkubak memiliki kandungan metabolit sekunder seperti alkaloid, flavonoid, steroid. Penelitian ini bertujuan untuk mengetahui efek antimikroba ekstrak metanol daun sengkubak (Pycnarrhena cauliflora) terhadap bakteri E. coli dan S. aureus dan untuk mengetahui konsentrasi efektif ekstrak dalam menghambat pertumbuhan bakteri E. coli dan S. aureus sebagai alternatif lain pengganti antibiotik. Penelitian ini dilakukan dari bulan April sampai Agustus 2021. Penelitian ini terdiri dari 7 taraf perlakuan yaitu kontrol positif (ciprofloxacin) 5µg/mL, kontrol negatif (DMSO 10%) dan konsentrasi ekstrak untuk uji E. coli yaitu 0,5; 1; 1,5; 2 dan 2,5 g/mL. Konsentrasi ekstrak untuk uji S. aureus yaitu 0,3; 0,4; 0,5; 0,6 dan 0,7 g/mL. Berdasarkan hasil penelitian menunjukkan bahwa ekstrak metanol daun sengkubak memberikan aktivitas antibakteri terhadap bakteri E. coli dan S. aureus. Konsentrasi efektif untuk menghambat bakteri E. coli dan S. aureus sebesar 0,5 g/mL dan 0,3 g/mL dengan diameter zona hambat sebesar 13,9 mm dan 12,6 mm dengan kategori aktivitas daya hambat ekstrak kuat.
Oxytocin and vasopressin levels in maltreated children: A systematic review
Authors: Beyazıt Utku , Kuru Alev , İlhan Ildız Gökçen , Uzun Mehmet Erdem , Şirin Hande , Bütün Ayhan Aynur , Yılmaz Serkan 
Published: June 2023

Objective: The present study aimed to focus on the neurobiological basis of childhood maltreatment. Method: A systematic review approach was followed by focusing on the possible links among oxytocin, vasopressin, and child maltreatment. The review included research based on data examining the role that being exposed to any kind of maltreatment during childhood plays. The review was not limited to a specific period. However, reviews, systematic reviews, dissertations, congress papers, and studies in languages other than Turkish and English were excluded. The search was concentrated on the Web of Science, PubMed, Science Direct, Scopus, EBSCO Host, and Google Scholar databases including the keyword combinations. Results: The review between December 2021 and April 2022 revealed 49 research studies that reported data from a total of 13979 participants (3981 children and adolescents, 9998 adults). Studies reviewed contained demographically diverse samples from a wide range of Western cultural contexts. Conclusion: The findings are promising in terms of clinical implications as there are considerable links between OXT and child maltreatment. However, more studies are needed to understand the nature of these links.
Assessment of the influence of the ADC resolution of the coherent radar on the accuracy of determining the coordinate of the projectile flight
Authors: Hrabchak Volodymyr , Kosovtsov Andriy , Hrabchak Zinaida 
Published: June 2023

The article considers the development of a heavy-class robotic ground combat system based on the BTR-4E armored personnel carrier. Analysis of samples the heavy class combat robotic ground complexes showed that they can be developed on the basis of serial crewed military vehicles HMMWV (AM General), M-ATV (Oshkosh), BMP-3 (Russia), T-72 (Russia), M113 (Israel), Patria AMV (Finland) or create a new design MDARS (AM General), Black Knight (BAE Systems), "Uran-9" (Russia), TYPE-X (Milrem Robotics). They are made on a tracked or wheeled platform. What unites this class of robotic ground combat systems is a remotely controlled combat module with a 25-30 mm cannon, anti-tank guided missiles, a machine gun and a grenade launcher, which can be controlled from a distance.
A comparative analysis of the tactical and technical characteristics the BTR-4E armored personnel carrier with military vehicles with a 30 mm cannon in service with the Armed Forces of Ukraine has been performed. As a result, the choice of BTR-4E armored personnel carrier as the basic crew unit for the construction of a heavy class robotic ground combat system has been substantiated.The analysis of the design of control drives of the power plant, transmission, braking system, steering system and combat module installed on the BTR-4E armored personnel carrier was carried out in terms of the possibility of implementing remote control of movement and fire.
The structure of a combat ground robotic complex based on the BTR-4E armored personnel carrier with different variants of remote control panels, means of establishing communication channels and construction of a remote control station is proposed.
For example, the driver's remote control panel may be designed on the basis a tablet or on the basis a simulator for full simulation of control commands. Remote controls for the commander and gunner can be designed on the basis of regular controls and be similar to them for quick training of the crew to work.
Communication between remote control units and the controlled armored personnel carrier can be arranged using ultrashort-wave radios or via the 4G, 5G mobile network.
The remote control point can also be developed on the basis a BTR-4E armored personnel carrier, a military vehicle or deployed on the ground. It depends on the concept of application of the heavy class combat ground robotic complex.
ІСТОРІЯ МОДЕРНІЗАЦІЇ ТАНКІВ Т-72 В УКРАЇНІ
Authors: Кікавський Андрій Григорович 
Published: June 2023

У статті розглянуті питання та ряд аспектів програм модернізації танків Т-72 в Україні, передумови створення варіантів модернізації, їх реалізація та розвиток. Після розпаду срср Україна отримала досить численний танковий парк основних бойових танків Т-64/72/80 та їх модифікацій з різними силовими установками, ходовими частинами та комплексами озброєння. Парк танків Т-72 налічував близько 800 одиниць. Вище керівництво вбачало в цьому значний експортний потенціал не тільки в базовому варіанті, але у розробці проєктів модернізації, в тому числі з залученням зарубіжних країн, що відчутно покращувало бойові та експлуатаційні характеристики Т-72 з урахуванням сучасних вимог до основних бойових танків.
Development of an alginate-Matrigel hydrogel system to evaluate cancer cell behavior in the stiffness range of the bone marrow
Authors: Northcutt Logan A. , Questell Alyssa M. , Rhoades Julie , Rafat Marjan 
Published: June 2023

Bone metastasis is highly prevalent in breast cancer patients with metastatic disease. These metastatic cells may eventually form osteolytic lesions and affect the integrity of the bone, causing pathological fractures and impairing patient quality of life. Although some mechanisms have been determined in the metastatic cascade to the bone, little is known about how the mechanical cues of the bone marrow microenvironment influence tumor cell growth and invasion once they have homed to the secondary site. The mechanical properties within the bone marrow range from 0.5 kPa in the sinusoidal region to 40 kPa in the endosteal region. Here, we report an alginate-Matrigel hydrogel that can be modulated to the stiffness range of the bone marrow and used to evaluate tumor cell behavior. We fabricated alginate-Matrigel hydrogels with varying calcium sulfate (CaSO4) concentrations to tune stiffness, and we demonstrated that these hydrogels recapitulated the mechanical properties observed in the bone marrow microenvironment (0.7–16 kPa). We encapsulated multiple breast cancer cell lines into these hydrogels to assess growth and invasion. Tumor cells in stiffer hydrogels exhibited increased proliferation and enhanced elongation compared to lower stiffness hydrogels, which suggests that stiffer environments in the bone marrow promote cellular invasive capacity. This work establishes a system that replicates bone marrow mechanical properties to elucidate the physical factors that contribute to metastatic growth.