bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and imaging outcomes of self-locking stand-alone cages and anterior cage-with-plate in three-level anterior cervical discectomy and fusion: a retrospective comparative study
Authors: Tang Liang , Liu Xiaoming , Lu Yanghu , Liu Yanbin , Yu Jiangming , Zhao Jian 
Published: April 2023

Abstract
Background
Anterior cervical discectomy and fusion has been considered standard management for cervical myelopathy and radiculopathy. However, the option of using self-locking stand-alone cages or cage-with-plate in three-level anterior cervical discectomy and fusion still remains controversial. The aim of this study was to evaluate the clinical and imaging outcomes of the two procedures in multilevel anterior cervical discectomy and fusion.

Methods
Sixty-seven patients who underwent three-level anterior cervical discectomy and fusion were enrolled in this study, of which 31 patients underwent surgery using self-locking stand-alone cages (group cage) and 36 patients using cage-with-plate (group plate). For the evaluation of clinical outcomes, modified Japanese Orthopedic Association scores, visual analogue scale for neck pain, neck disability index, Odom’s criteria and dysphagia status were measured. Imaging outcomes were evaluated by cervical sagittal angle, fusion segmental Cobb’s angle, fusion segmental height, range of motion, cage subsidence rate, fusion rate and adjacent segment degeneration. Statistical analyses were performed using the SPSS software (version 19.0).

Results
Both groups showed improvement in modified Japanese Orthopedic Association scores, visual analogue scale for neck pain and neck disability index, after surgery, and there was no significant difference between the groups. The occurrence rate of dysphagia is significantly lower in the group cage compared with the group plate (p < 0.05). The postoperative cervical sagittal angle, fusion segmental Cobb’s angle, fusion segmental height and cage subsidence rate in the group plate were significantly superior to that in the group cage (p < 0.05). However, the rate of adjacent segment degeneration was significantly lower in the group cage compared with the group plate (p < 0.05). Both groups showed no significant difference in terms of fusion rate (p > 0.05).

Conclusions
The self-locking stand-alone cages are effective, reliable and safe in anterior cervical discectomy and fusion for the treatment of cervical myelopathy and radiculopathy. Self-locking stand-alone cages showed a significantly lower rate of dysphagia and adjacent segment degeneration, while anterior cervical cage-with-plate could provide stronger postoperative stability and maintain better cervical spine alignment.
Evaluating remote post-mortem veterinary meat inspections on pig carcasses using pre-recorded video material
Authors: Almqvist Viktor , Berg Charlotte , Kautto Arja Helena , Hultgren Jan 
Published: April 2023

Abstract
Background
Official meat inspections at small-scale slaughterhouses and game-handling establishments in geographically remote areas place a heavy burden on the meat-producing food business operators. By performing meat inspections remotely using live-streamed video, instead of on-site, the official control could meet the goals of sustainability, resilience and logistics. We investigated the agreement between the two approaches at pig slaughter. Two official veterinarians (OVs) inspected 400 pig carcasses at a Swedish slaughterhouse, with each pig being inspected on site by one OV and remotely by the other. After a period of 3 to 6 months, video recordings of the remote inspections were assessed again by the same OVs, thus enabling direct comparisons of previous on-site inspections and renewed video-based inspections within the same OV.

Results
Agreement across 22 finding codes was generally very high for both OVs. In all but one case (whether to fully condemn a carcass), for both OVs, Prevalence-Adjusted Bias-Adjusted kappa was well above 0.8, indicating ‘almost perfect agreement’.

Conclusions
This study supports earlier findings that reliable post-mortem inspections can be performed using video, and indicates higher agreement between remote and on-site inspections if the same OV performs both.
External validation of the PROLOGUE score to predict neurological outcome in adult patients after cardiac arrest: a prospective cohort study
Authors: Blatter René , Gökduman Bulus , Amacher Simon A. , Becker Christoph , Beck Katharina , Gross Sebastian , Tisljar Kai , Sutter Raoul , Pargger Hans , Marsch Stephan , Hunziker Sabina 
Published: April 2023

Abstract
Background
The PROLOGUE score (PROgnostication using LOGistic regression model for Unselected adult cardiac arrest patients in the Early stages) is a novel prognostic model for the prediction of neurological outcome after cardiac arrest, which showed exceptional performance in the internal validation. The aim of this study is to validate the PROLOGUE score in an independent cohort of unselected adult cardiac arrest patients and to compare it to the thoroughly validated Out-of-Hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP) scores.

Methods
This study included consecutive adult cardiac arrest patients admitted to the intensive care unit (ICU) of a Swiss tertiary teaching hospital between October 2012 and July 2022. The primary endpoint was poor neurological outcome at hospital discharge, defined as a Cerebral Performance Category (CPC) score of 3 to 5 including death.

Results
Of 687 patients included in the analysis, 321 (46.7%) survived to hospital discharge with good neurological outcome, 68 (9.9%) survived with poor neurological outcome and 298 (43.4%) died. The PROLOGUE score showed an area under the receiver operating characteristic curve (AUROC) of 0.83 (95% CI 0.80 to 0.86) and good calibration for the prediction of the primary outcome. The OHCA and CAHP score showed similar performance (AUROC 0.83 and 0.84 respectively), the differences between the three scores were not significant (p = 0.495). In a subgroup analysis, the PROLOGUE score performed equally in out-of-hospital and in-hospital cardiac arrest patients whereas the OHCA and CAHP score performed significantly better in OHCA patients.

Conclusion
The PROLOGUE score showed good prognostic accuracy for the early prediction of neurological outcome in adult cardiac arrest survivors in our cohort and might support early goals-of-care discussions in the ICU.
Trial registration Not applicable.
Individual psychotherapy for cluster-C personality disorders: protocol of a pragmatic RCT comparing short-term psychodynamic supportive psychotherapy, affect phobia therapy and schema therapy (I-FORCE)
Authors: Daniëls Martine , Van Henricus L. , van den Heuvel Birre , Dekker Jack J. M. , Peen Jaap , Bosmans Judith , Arntz Arnoud , Huibers Marcus J. H. 
Published: April 2023

AbstractBackgroundCluster-C personality disorders (PDs) are highly prevalent in clinical practice and are associated with unfavourable outcome and chronicity of all common mental health disorders (e.g. depression and anxiety disorders). Although several forms of individual psychotherapy are commonly offered in clinical practice for this population, evidence for differential effectiveness of different forms of psychotherapy is lacking. Also, very little is known about the underlying working mechanisms of these psychotherapies. Finding evidence on the differential (cost)-effectiveness for this group of patients and the working mechanisms of change is important to improve the quality of care for this vulnerable group of patients.ObjectiveIn this study, we will compare the differential (cost)-effectiveness of three individual psychotherapies: short-term psychodynamic supportive psychotherapy (SPSP), affect phobia therapy (APT) and schema therapy (ST). Although these psychotherapies are commonly used in clinical practice, evidence for the Cluster-C PDs is limited. Additionally, we will investigate predictive factors, non-specific and therapy-specific mediators.MethodsThis is a mono-centre randomized clinical trial with three parallel groups: (1) SPSP, (2) APT, (3) ST. Randomization on patient level will be pre-stratified according to type of PD. The total study population to be included consists of 264 patients with Cluster-C PDs or other specified PD with mainly Cluster-C traits, aged 18–65 years, seeking treatment at NPI, a Dutch mental health care institute specialized in PDs. SPSP, APT and ST (50 sessions per treatment) are offered twice a week in sessions of 50 min for the first 4 to 5 months. After that, session frequency decreases to once a week. All treatments have a maximum duration of 1 year. Change in the severity of the PD (ADP-IV) will be the primary outcome measure. Secondary outcome measures are personality functioning, psychiatric symptoms and quality of life. Several potential mediators, predictors and moderators of outcome are also assessed. The effectiveness study is complemented with a cost-effectiveness/utility study, using both clinical effects and quality-adjusted life-years, and primarily based on a societal approach. Assessments will take place at baseline, start of treatment and at 1, 3, 6, 9, 12, 18, 24 and 36 months.DiscussionThis is the first study comparing psychodynamic treatment to schema therapy for Cluster-C PDs. The naturalistic design enhances the clinical validity of the outcome. A limitation is the lack of a control group for ethical reasons.Trial registrationNL72823.029.20 [Registry ID: CCMO]. Registered on 31 August 2020. First participant included on 23 October 2020.
Early weaning causes small intestinal atrophy by inhibiting the activity of intestinal stem cells: involvement of Wnt/β-catenin signaling
Authors: Tian Junquan , Li Yuying , Bao Xuetai , Yang Fan , Tang Xiongzhuo , Jiang Qian , Yin Yulong , Yao Kang 
Published: April 2023

Abstract
Background
Early weaning and shorter breastfeeding duration are applied by a proportion of young mothers, especially in the social spheres of poverty-stricken areas. Early childhood is a critical period for intestinal development, which is driven by intestinal stem cells (ISCs). However, how early weaning practice affects the function of ISCs to mediate intestinal development remains unclear.

Methods
We established an excellent early weaning mice model that has significant intestinal atrophy and growth arrest symptoms to explore the responses of ISCs to early weaning. The primary and passaged intestinal organoids from the suckling or early weaning mice were cultured to explore the underlying mechanism of early weaning affecting the ISCs.

Results
Early weaning depressed the self-renewal of ISCs and attenuated the activity of ISCs-driven intestinal epithelial regeneration and crypt expansion in vivo and ex-vivo. Further results showed that early weaning retarded the differentiation of ISCs into transit-amplifying cells and Paneth cells, and accelerated the apoptosis of villous epithelial cells, jointly leading to intestinal epithelial atrophy. Mechanistically, early weaning inhibited Wnt signaling in ISCs, while an exogenous Wnt amplifier restored ISCs’ function in ex-vivo.

Conclusion
Our findings indicate that early weaning depresses the activity of ISCs via attenuating Wnt/β-catenin signaling and triggers the proinflammatory cytokines TNF-α, IL-1β, IL-6, and IL-17 in jejunum, thereby impeding ISCs-driven epithelial regeneration and intestinal growth, which may provide a basal theory for the development of infant nutrients targeting stem cells to alleviate early weaning-induced intestinal problems.
Vehicle logo detection using an IoAverage loss on dataset VLD100K-61
Authors: Shi Xiaohui , Ma Shengli , Shen Yang , Yang Yankun , Tan Zexin 
Published: April 2023

AbstractVehicle Logo Detection (VLD) is of great significance to Intelligent Transportation Systems (ITS). Although many methods have been proposed for VLD, it remains a challenging problem. To improve the VLD accuracy, an Intersection over Average (IoAverage) loss is proposed for enhancing the bounding box regression. The IoAverage loss accelerates the convergence of bounding box regression than using the Intersection over Union (IoU) loss. In the experiments, IoAverage loss has been incorporated into the state-of-the-art object detection framework YOLOV5s, namely YOLOV5s-IoAv in this paper. The advantages of the IoAverage loss are verified on the PASCAL VOC2007 datasets. The results of using the IoAverage loss show performance gains of + 15.27% mAP0.5 and + 30.87% mAP0.5:0.95 higher than that of the Complete IoU (CIoU) loss. The application of YOLOV5s-IoAv is implemented to VLD on dataset VLD100K-61. VLD100K-61 is a self-collected dataset containing 100,041 images supplied by traffic surveillance cameras in the real world from 61 categories. YOLOV5s-IoAv achieves performance gains as + 15.27% mAP0.5:0.95 for VLD than YOLOV5s-CIoU. The proposed method yields the mAP0.5 value of up to 0.992 on the dataset VLD100K-61, providing a promising solution to vehicle logo recognition applications.
Blow-up of solutions to the semilinear wave equation with scale invariant damping on exterior domain
Authors: Ren Cui , Ming Sen , Fan Xiongmei , Du Jiayi 
Published: April 2023

AbstractThis paper is concerned with the blow-up of solutions to the initial boundary value problem for the wave equation with scale invariant damping term on the exterior domain, where the nonlinear terms are power nonlinearity $|u|^{p} $

|
u
|

p

, derivative nonlinearity $|u_{t}|^{p} $

|

u
t

|

p

and combined nonlinearities $|u_{t}|^{p}+ |u|^{q} $

|

u
t

|

p

+

|
u
|

q

, respectively. Upper bound lifespan estimates of solutions to the problem are obtained by constructing suitable test functions and utilizing the test function technique. The main novelty is that lifespan estimates of solutions are associated with the well-known Strauss exponent and Glassey exponent. To the best of our knowledge, the results in Theorems 1.1–1.3 are new.
Acceptability of mandatory vaccination against influenza, measles, pertussis and varicella by workers in healthcare facilities: a national cross-sectional study, France, 2019
Authors: Vaux Sophie , Fonteneau Laure , Péfau Muriel , Venier Anne-Gaëlle , Gautier Arnaud , Altrach Sophan Soing , Parneix Pierre , Levy-Bruhl Daniel 
Published: April 2023

Abstract
Background
Vaccination of healthcare workers (HCW) aims to protect them and to reduce transmission to susceptible patients. Influenza, measles, pertussis, and varicella vaccinations are recommended but not mandatory for HCW in France. Insufficient vaccine coverage for these diseases in HCW has raised the question of introducing mandatory vaccination. We conducted a survey to estimate acceptability of mandatory vaccination for these four vaccines by HCW working in healthcare facilities (HCF) in France, and to identify associated determinants.

Methods
In 2019, we performed a cross-sectional survey of physicians, nurses, midwives and nursing assistants working in HCF in France using a randomised stratified three-stage sampling design (HCF type, ward category, HCW category). Data were collected in face-to-face interviews using a tablet computer. We investigated the possible determinants of acceptability of mandatory vaccination using univariate and multivariate Poisson regressions, and estimated prevalence ratios (PR).

Results
A total of 8594 HCW in 167 HCF were included. For measles, pertussis, and varicella, self-reported acceptability of mandatory vaccination (very or quite favourable) was 73.1% [CI95%: 70.9–75.1], 72.1% [69.8–74.3], and 57.5% [54.5–57.7], respectively. Acceptability varied according to i) HCW and ward category for these three vaccinations, ii) age group for measles and pertussis, and iii) sex for varicella. For mandatory influenza vaccination, acceptability was lower (42.7% [40.6–44.9]), and varied greatly between HCW categories (from 77.2% for physicians to 32.0% for nursing assistants).

Conclusion
HCW acceptability of mandatory vaccination was high for measles, pertussis and varicella but not as high for influenza. Vaccination for COVID-19 is mandatory for HCW in France. Replication of this study after the end of the COVID-19 crisis would help assess whether the pandemic had an impact on their acceptability of mandatory vaccination, in particular for influenza.
Changes in selection of resources with reproductive state in a montane ungulate
Authors: Blum Marcus E. , Stewart Kelley M. , Shoemaker Kevin T. , Cox Mike , Wakeling Brian F. , Dilts Thomas E. , Bennett Joe R. , Bleich Vernon C. 
Published: April 2023

AbstractAnimals select habitats based on food, water, space, and cover. Each of those components are essential to the ability of an individual to survive and reproduce in a particular habitat. Selection of resources is linked to reproductive fitness and individuals likely vary in how they select resources relative to their reproductive state: during pregnancy, while provisioning young when nutritional needs of the mother are high, but offspring are vulnerable to predation, or if they lose young to mortality. We investigated the effects of reproductive state on selection of resources by maternal female desert bighorn sheep (Ovis canadensis nelsoni) by comparing selection during the last trimester of gestation, following parturition when females were provisioning dependent young, and if the female lost an offspring. We captured, and recaptured each year, 32 female bighorn sheep at Lone Mountain, Nevada, during 2016–2018. Captured females were fit with GPS collars and those that were pregnant received vaginal implant transmitters. We used a Bayesian approach to estimate differences in selection between females provisioning and not provisioning offspring, as well as the length of time it took for females with offspring to return levels of selection similar to that observed prior to parturition. Females that were not provisioning offspring selected areas with higher risk of predation, but greater nutritional resources than those that were provisioning dependent young. When females were provisioning young immediately following parturition, females selected areas that were safe from predators, but had lower nutritional resources. Females displayed varying rates of return to selection strategies associated with access to nutritional resources as young grew and became more agile and less dependent on mothers. We observed clear and substantial shifts in selection of resources associated with reproductive state, and females exhibited tradeoffs in favor of areas that were safer from predators when provisioning dependent young despite loss of nutritional resources to support lactation. As young grew and became less vulnerable to predators, females returned to levels of selection that provided access to nutritional resources to restore somatic reserves lost during lactation.
The effect of wearable technology on badminton learning performance: a multiple feedback WISER model in physical education
Authors: Lin Kuo-Chin , Hung Hui-Chun , Chen Nian-Shing 
Published: April 2023

AbstractTraditional physical education mainly relies on the instructor’s verbal explanations and physical demonstrations. However, learners might be confused about whether their movements and positions are correct. Moreover, a typical badminton class has approximately 50 students, creating a huge teaching load for an instructor. To reduce the instructor’s workload and improve learners’ badminton performance, a multiple feedback WISER model was designed for badminton classes. The model provides visual feedback, information feedback, and verbal guidance to learners. In this study, a quasi-experiment was designed and participants were divided into experimental and control groups. The experimental group adopted the multiple feedback WISER model while the control group applied the conventional method. The teaching experiment lasted for 8 weeks with 46 participants in the experimental group and 50 participants in the control group, respectively. To measure the learning performance, a movement detection system using wearable technology was utilized. The results indicate that the experimental group, which used the multiple feedback WISER model, outperformed the control group, which used traditional teaching methods, on badminton clear and smash skill learning (Clear: p < .001, EG = 71.03, CG = 54.76; Smash: p < .01, EG = 82.79, CG = 72.22). Further analysis reveals that the multiple feedback is more beneficial for learners with lower initial skill levels (Clear: p < .05, Lower = 63.21, Higher = 46.99; Smash: p < .001, Lower = 77.67, Higher = 39.39)
So, you want to get into “total-body” PET/CT scanning? An installation guide for beginners!
Authors: Hicks Rodney J. 
Published: April 2023

Abstract“Total-body” and ultra-extended field-of-view PET/CT scanners are now available commercially with great enthusiasm for their potential in both streamlining clinical practice and providing unique research opportunities. Accordingly, many groups are rushing to implement this technology. For early adopters, the challenges of these systems compared with more standard PET/CT systems have been significant. In this guide, aspects that need to be considered in planning installation of one of these scanners are discussed. These include financing, space, structural engineering, power supply, chilled water and environmental controls to manage heat loads, IT infrastructure and data storage, radiation safety and radiopharmaceutical procurement, staffing levels, patient handling logistics and imaging protocol redesign to leverage the superior sensitivity of these scanners, and marketing. It is a daunting but worthwhile endeavor in the author’s opinion but needs a great team and the ability to bring in the appropriate expertise at the appropriate time.
Development of particle swarm clustered optimization method for applications in applied sciences
Authors: Mahdavi-Meymand Amin , Sulisz Wojciech 
Published: April 2023

AbstractAn original particle swarm clustered optimization (PSCO) method has been developed for the implementations in applied sciences. The developed PSCO does not trap in local solutions in contrary to corresponding solutions obtained by the applications of particle swarm optimization algorithm that is frequently used in many disciplines of applied sciences. The integrations of PSCO with multilayer perceptron neural network, adaptive neuro-fuzzy inference system (ANFIS), linear equation, and nonlinear equation were applied to predict the Vistula river discharge. The performance of PSCO was also compared with autonomous groups particle swarm optimization, dwarf mongoose optimization algorithm, and weighted mean of vectors. The results indicate that the PSCO has no tendency to trap in local solutions and its global solutions are more accurate than other algorithms. The accuracy of all developed models in predicting river discharge was acceptable (R2 > 0.9). However, the derived nonlinear models are more accurate. The outcome of thirty consecutive runs shows that the derived PSCO improves the performance of machine learning techniques. The results also show that ANFIS-PSCO with RMSE = 108.433 and R2 = 0.961 is the most accurate model.