bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the success rate of various inpatient alcohol addiction treatment programs in the Czech Republic and their comparison
Authors: Skorkovsky T. , Vevera J. , Benis M. , Miovsky M. , Popov P. 
Published: August 2023

IntroductionHarmful alcohol use far exceeds other mental disorders in the proportion of patients who do not receive adequate treatment. Despite the long history of anti-alcohol treatment in Czech Republic, there is no published prospective study to this day, in which patients that underwent inpatient addiction treatment are compared to patients on the waiting list and only one prospective randomized study comparing two different medium-term inpatient programs was published.Almost all the studies published so far only bring results of particular hospitals. Differences in methodology, differences between cohorts of patients, absence of profiling and differences in therapeutic programs and historical changes makes comparison of results of those studies very difficult.ObjectivesThis work seeks to present and compare the data from studies that evaluate the success of medium-term inpatient treatment of alcohol dependent patients in the Czech Republic. Another aim was to identify problems that make such comparison difficult.MethodsBibliographia Medica Čechoslovaca and Pubmed was used to find studies published in professional medical journals since 1970, in which abstinence of patients who voluntarily completed medium-term inpatient treatment of alcohol dependence is evaluated.ResultsMedium-term inpatient treatment of alcohol addiction leads to one year abstinence in 34 to 76 % of patients. Such variance value is largely caused by different methodology of compared studies. In compared studies there are differences:1. in definition of abstinence2. if abstinence rate is assessed in all patients who have entered the treatment or only in those who have completed the treatment properly3. if abstinence rate is calculated using number of patients entering treatment or the number of patients who have been obtained by valid information (outpatient clinic, questionnaires)4. in the way the data was collected5. in the composition of patients6. in societal background, because there is large time gap present between compared studiesConclusionsThe comparison of individual studies presented many problems. Further steps should be taken to help compare treatment programs in the future, as they provide different therapeutic interventions in different intensity and length to different patients. Adequate patient profiling, detailed description of therapeutic interventions and identification of effective components of the therapeutic program is a way to support further research in this area, optimize existing programs and increase the overall efficiency of treatment.Disclosure of InterestNone Declared
Mental health and addiction in young refugees-Research on prevalence of alcohol and substance use, PTSD and psychological difficulties experienced by young migrants and refugees placed in two refugee centers in Serbia in the time of COVID-19 pandemic
Authors: Vasic J. , Grujicic Roberto , Toskovic Oliver , Milovancevic Milica Pejovic 
Published: August 2023

Abstract: IntroductionAs the global resettlement needs are further increasing, the questions on refugee youths’ wellbeing arise. The experience of migration during childhood might interfere with the developmental trajectories in different ways. Refugee youths might be at higher risk of violence, abuse and mental health problems.ObjectivesThis study aimed to explore the prevalence of alcohol and substance use among young refugees, along with the indicators of experienced psychological difficulties.MethodsData collection was followed by numerous difficulties–C-19 pandemic, linguistic diversity and high respondents’ illiteracy rate.ResultsThe sample consisted of 184 participants aged 11–18 years. More than a half of them displayed symptoms of PTSD - more frequently females, those who resided in a greater number of refugee centers and those who were exposed to abuse and domestic violence. Half of the respondents consumed energy drinks, slightly less than a third of them used tobacco, 13% consumed alcohol, 4.6% marijuana, whereby the frequency of other substance use was significantly lower. The significant indicators of individual propensity to use alcohol and substances were shown to be older age (14-18 years), male gender, lower education, being unaccompanied child and exposure to emotional abuse.ConclusionsOur research confirmed that young refugees, especially unaccompanied, might be at higher risk for mental health difficulties. Research on this topic should aim to link scientific data to sustainable practices, applicable in everyday life.Disclosure of InterestNone Declared
Comorbid anxiety has schizophrenia diagnosis and management modality
Authors: Korchi A. , Laboudi F. , Ouanass A. 
Published: August 2023

IntroductionSchizophrenia is a chronic psychiatric disorder with disorganization progressive and important affecting several spheres: thought, affectivity, cognition and social life of the subject. It is a serious mental disorder with a prevalence of nearly 1%.Men would present more premorbid difficulties, but the overall prevalence of symptoms of schizophrenia is similar in both sexes.When it comes to comorbidity, men and women are vulnerable to somewhat different health issues.Anxiety symptoms are one of the main symptoms in patients with schizophrenia, but the effect of anxiety symptoms on patients is easily overlooked.About 40% have persistent anxiety symptoms in patients with schizophrenia, and whether they are accompanied depressive symptoms, the symptoms may have a greater impact on the patients. We need to help patients avoid suicide when the symptoms depression appear.Hallucinations auditory, anxiety symptoms and depressive symptoms may exist simultaneously in patients with schizophrenia.Most studies focus on studying the relationship between auditory hallucinatory symptoms and depressive symptoms in patients with schizophrenia, the relationship between auditory hallucinatory symptoms and anxiety symptoms, or the relationship between anxiety symptoms and symptoms depressiveObjectivesThe objective of this study is to resolve important questions concerning the interaction of anxiety and schizophrenia in patients followed in psychiatry at Arrazi Hospital .MethodsDescriptive and analytical cross-sectional study, conducted over a period from May 2022 to October 2022 in patients consulted in Arrazi de Salé, using a questionnaire grouping together the sociodemographic characteristics, the risks and the advantages of antipsychotics, medical comorbidities and the mobilization of psychosocial support, and thus the BPRS Anxiety Rating Scale.ResultsOf the 42 patients who completed the study, 18 were female and 24 were male 60% were single. The average age was 36.63 years, 60% have secondary education, 25% primary, and 15% university level, 30% have a family history of schizophrenia.32 were taking an atypical antipsychotic, 10 were taking classic neuroleptics.Most schizophrenics encountered in psychiatry are stabilized on antipsychotic treatment, and those who have an anxious comorbidity are still too often underestimated , put on the account of the positive symptoms and the negative symptoms of schizophrenia, it is insufficiently diagnosed and treated.The effect of anxiety symptoms on patients is easily overlooked.It should be kept in mind that anxiety in schizophrenia requires special attention when discussing and prescribing antipsychotic medications.ConclusionsOptimal interventions for patients with comorbid schizophrenia and anxiety differ by quality of life.At all consultations, preventive strategies should consider mindful interviews and the risks and benefits of treatment for schizophrenia and comorbidities.Disclosure of InterestNone Declared
TELE-PSYCHOTHERAPY OF ANXIETY AND DEPRESSION DISORDERS
Authors: Lancia I. S. , Festa G. M. , Attouchi A. , Civino M. 
Published: August 2023

IntroductionThe process of integrating technology into mental health pathways represents a social transformation that we are gradually getting used to. But does it represent a valid alternative to face-to-face care processes? In this paper we will consider telesychology as a tool for treating anxiety and depression and its validity. Anxiety and depression are harmful to individuals, suffering from these disorders, their caregivers, and the economy. Remote delivery of psychotherapy has been established as a viable alternative to traditional in-person psychotherapy for treating anxiety and depression. However, literature comparing and evaluating the variety of remote delivery modalities of psychotherapy has not yet been integrated.ObjectivesThis review examines the efficiency – to - practice and the limits of e-therapy and its mediums: telephone, video, and online-administered psychotherapy, for treatment of anxiety and depression.MethodsA comprehensive literature search, conducted using PubMed and PsycINFO included systematic reviews, randomized controlled trials, and cost-analysis studies focused on a remote delivery method of e-psychotherapy for anxiety and depressionResultsOverall, interventions delivered through telephone, video, and online modalities, have generally demonstrated good efficiency in treating anxiety and depression; also comorbid with other disorders. The literature also suggested that telehealth psychotherapy is accessible, convenient, and cost-effective.In evaluating the reviews on the databases, it also emerged that among the many psychological therapies for anxiety disorders, delivered digitally (CBT, Attention bias modification, Exposure therapy, Applied relaxation, Bibliotherapy, Psychodynamic therapy, Mindfulness, Behavioral stress management, Counseling), the best digital therapy is internet-based cognitive behavioral therapy (iCBT), in particular for Social Anxiety Disorder (SAD).Despite this, overall, the efficiency and practical benefits of remote psychotherapy interventions in treating anxiety and depression across a diverse range of patient groups suggested that it is an appropriate alternative for those who cannot access in-person psychotherapy.ConclusionsFurther research evaluating the efficiency and practical benefits of e-psychotherapy for anxiety and depression is much needed for patients with limited access to in-person psychological care. Moreover, it remains to evaluate the maintenance of therapeutic gains after the end of the treatments.Disclosure of InterestNone Declared
Anxiety and depressive disorders Screening among Healthcare Professionals
Authors: Ayed W. , Chebbi S. , Ayadi A. , Ayari S. , Kebir H. , Magroun I. 
Published: August 2023

IntroductionStress is an integral part of the profession of health care personnel (HCP) and manifests in higher rates of depressive and anxiety disorders (ADD).ObjectivesScreening of anxiety and depressive disorders factors among HCPsMethodsA descriptive cross-sectional study in two university hospitals in Ariana was carried out ont september 2022. It included HCP who were examined for medical periodic visit. Data was collect from medical records, anxiety and depression Scale (HAD) and somnolence questionnaire (Epworth).ResultsOne hundred and nine HCP were included in the study. Women represented 87.2% of cases. The average age was 38 ±10.7 years. The average occupational seniority varied between one to 38 years. Nurses represented 38.5%, technicians 24% and doctors 7%. They had night work in 12% of cases. Depression and anxiety were found for 20% and 31% of cases respectively. Successive daytime sleepiness was found in 7% of cases. A statistically significant relationship was found between excessive daytime sleepiness and anxiety (p=0.005) and between depression (p=0.002).ConclusionsAnxiety and depressive disorders in HCP were considerable. they were assiciated with sleepiness disorder. Night or day time shift wasn’t statistically correlated with ADD. Referral to psychiatric consultations after psychological opinion was done in order garantee therapeutic support and decide fitness to work.Disclosure of InterestNone Declared
Deep brain stimulation of the medial forebrain bundle - effects on suicidality in treatment-refractory MDD patients?
Authors: Soares J. C. 
Published: August 2023

AbstractDeep brain stimulation (DBS) of brain circuits involved in mood regulation is a novel tool that is being investigated as a potential treatment for some of the most severe patients with mood disorders. At UTHealth Houston, we have had an ongoing clinical trial with DBS of the medial forebrain bundle (MFB).Our preliminary results suggest effects in alleviating depressive symptoms in this very severe, refractory patient group.In this presentation, we will review our latest findings, and will also discuss the potential effects of the MFB stimulation on measures of suicidality in this patient population.Disclosure of InterestNone Declared
Long-acting new generation antipsychotics in the maintenance treatment of bipolar disorders
Authors: Yavuz E. , Altınbaş K. 
Published: August 2023

IntroductionMaintaining remission, preventing from future episodes, better treatment adherence and improving the quality of life are main aims of long-term treatment in bipolar disorders (BD). In recent years, new generation long-acting injectable (LAI) antipsychotics have been frequently used in maintenance treatment for bipolar disorders.ObjectivesWe aimed to review socio-demographic and clinical characteristics of bipolar patients taking LAI treatment for maintenance treatment.MethodsClinical records of 56 bipolar patients who are on LAI treatment and followed in Mazhar Osman Mood Clinic (MOMC) of Selcuk University Medical Faculty were evaluated. Descriptive statistical analysis was performed with Statistical Package for the Social Sciences (SPSS).ResultsNearly half of the patients were male (n:29, 52%). 49,1% of the patients were married. The mean age was 37.1±12.2 years and the mean duration of education was 11.1±4.2 years. All of the patients were diagnosed with bipolar 1 disorder. Most of the patients (64,7%) was on aripiprazole LAI while remaining was receiving paliperidone LAI for maintenance treatment. We found a significant reduction in the number of manic episodes after long-acting treatment (p<0.001), but we could not find any difference for depression. Ten of the patients discontinued the treatment due to the side effects, extrapyramidal side effects were the most common side effects. Eight of the patients were switched from paliperidone treatment to aripiprazole treatment due to side effects, especially hyperprolactinemia. Relapse was observed in 46,4% of the patients and there was no difference between aripiprazole and paliperidone in terms of relapse rate.ConclusionsLAI new generation antipsychotics are taking place in long-term treatment of bipolar disorder via improving treatment adherence. Side effect profile of aripiprazole and paliperidone are different. However, we could not find any difference between two drugs in terms of side effects and relapse rates. Small sample size and shorter duration of follow-up should be considered as limitations.Disclosure of InterestNone Declared
The current shapes of cyberviolence in digital relationships
Authors: Yilmaz Karaman I. G. 
Published: August 2023

AbstractSocial life has moved toward the digital world in many aspects. As the original inhabitants of virtual life, young people face several adversities while flirting and dating online. The anonymity of the online environment enables aggression without consequences. Cyberviolence has no boundaries as time or place. Thus it may cause psychological distress.Young people frequently use online dating and social networking sites, which makes them vulnerable to cyber dating violence, sextortion, and revenge porn. Cyberdating violence usually targets young women and girls. It is mainly related to stereotypical gender beliefs: presented as controlling behavior and psychological violence. Survivors of cyber dating violence tend to feel anger, hostility, and loneliness. Sextortion is image-based sexual abuse, which includes threats with intimate pictures or videos. Perpetrators of sextortion can be hackers, ex-partners, or admirers. Exposure to sextortion is related to shame, fear, and helplessness. Former partners may use revenge porn to control one’s behavior. It is another kind of image-based sexual abuse. Perpetrators may use nonconsensual pornography to punish or humiliate their ex-partners.Cyber victimization is as traumatic as real-life victimization. That results in depression, anxiety, and posttraumatic stress. Moreover, the absence of time and space restrictions can make cyberviolence even more debilitative. I aim to inform European psychiatrists about the current shapes of cyber psychological trauma in the context of online flirting and dating. So that psychiatrists can better understand its content and outcomes, especially while working with young people.Disclosure of InterestNone Declared
An Internet-Based Multi-Approach Intervention Targeting University Students Suffering from Psychological Problems: MindBlooming
Authors: Calati Raffaella , Fagadau Ionut Daniel , Ginelli Davide , Madeddu Fabio , Lopez-Castroman Jorge , Romano Daniele , Gabbiadini Alessandro , Preti Emanuele , Micucci Daniela 
Published: August 2023

AbstractThe young adult can experience psychological difficulties related to the delicate phase of life he/she is going through. Many of them show psychological difficulties but only a small portion receive the needed care. In this regard, internet-based interventions represent an important resource.MindBlooming is a seven-week intervention delivered through a mobile application for university students with mild to moderate psychological difficulties. The application is the result of the interdisciplinary work between the Department of Psychology and the Department of Informatics, Systems and Communication of the University of Milan-Bicocca.The intervention focused on symptoms of depression, anxiety, sleep problems, self-destructive thoughts, job- and study-related stress and burnout, and chronic pain. It is based on different approaches
(multi-approach), primarily psychoeducation, Cognitive-Behavioral Treatment (CBT), and third-wave CBT. During the first pilot study, the intervention consisted of a 7-week treatment on two problematic areas according to each students’ personal needs, identified through an initial assessment. The achieved results are promising especially in terms of interest shown by students. However, we encountered technical problems that hampered the pilot study. A second pilot will be performed to further test the application.The MindBlooming project will be discussed in light of the need for further multidisciplinary research that confirms how biomarkers can be sensitive to non-pharmacological internet-based interventions.Keywordscognitive-behavioral treatment; internet-based intervention; university students.Disclosure of InterestNone Declared
Life stress and Bipolar Disorder: regarding a clinical case
Authors: Coelho Rocha T. , Cunha J. F. , Torres S. , Alves Leal J. , Carvalho Moura J. , Seabra D. , Monteiro Lopes I. , Lopes A. , Lima G. 
Published: August 2023

IntroductionResearch on life stress in bipolar disorder largely fails to account for the possibility of a dynamic relationship between psychosocial stress and episode initiation. The kindling hypothesis states that over the course of recurrent affective disorders, there is a weakening temporal relationship between major life stress and episode initiation that could reflect either a progressive sensitization or progressive autonomy to life stress.ObjectivesTo explore the concept of the Kindling model applied to bipolar disorder and to present a clinical case of a bipolar patient whose latter mood episodes were caused by adverse life events.MethodsWe performed a non-systematic literature review using the most relevant papers found on the database PubMed with the keywords “kindling effect”, “allostatic load”, “bipolar disorder” and “prevention”. Description of the clinical case report.ResultsThe phenomenon of kindling was first discovered by Goddard in 1967 who described it in epilepsy. Later, Post applied it to the bipolar disorder, arguing that the initial episodes of both unipolar and bipolar affective disorders are often precipitated by psychosocial stressors, but after multiple recurrences, not only do precipitated episodes continue to occur, but so do spontaneous ones as well. We present the case report of a 62 years old woman, divorced, diagnosed with type 1 bipolar disorder since she was 20 years old. She always have had poor adherence to her medication and follow-up with Psychiatry consultation, with a non-containing sociofamily environment that does not promote clinical stability. Over the time, her admissions on the Psychiatry ward were more frequent and precipitated by adverse life events, mainly caused by the deteriorated relationship with her children.ConclusionsThe kindling model clarifies aspects of the longitudinal course of episode development, recurrence, and progression to spontaneity, as well as further conceptual and theoretical rationales for intervention in order to prevent illness progression.Disclosure of InterestNone Declared
Characteristics of early and late onset pediatric depression
Authors: Díaz-Castro L. , Hoffman K. L. 
Published: August 2023

IntroductionDepression, anxiety and suicide are serious psychiatric conditions that affect Mexican youth (Institute for Health Metrics and Evaluation, IHME, 2022), with depression showing a prevalence greater than 16%. Suicide ranks as the second most important cause of deathin this age group, (6/100,000 deaths), the first being violent deaths by firearms (15/100,000 deaths;IHME, 2022).ObjectivesTo identify factors related to age of onset of pediatric depression.MethodsA cross-sectional study was carried out during 2018-2020 in two Children’s Psychiatric Hospitals in Mexico City. Data were collected using a survey method. All participants signed an informed consent form. We applied Cox hazard analysis, with the hazard event being the onset of psychiatric symptoms.ResultsData from 400 patients were analyzed, 148 girls (37%) and 252 boys (63%). Mean patient age was 12 years, and mean age of symptom onset was 8 years. The most common diagnoses were hyperkinetic disorder (51%), depression (34%), and anxiety (7.8%). Age of depression onset was significantly reduced in association with male sex (HR=1.46), family history of psychiatric disorder (familial depression HR=2.34; hyperkinetic disorder HR=2.67; psychoactive substance abuse HR=5.09), and certain medical comorbidities (asthma HR=6.41; enuresis HR=3.03). These same covariates were not associated with age of onset of hyperkinetic disorder or anxiety.ConclusionsThese analyses indicate that a subgroup of pediatric depression has an early onset and is associated with familial hyperkinetic disorder and depression, the male sex, and certain medical comorbidities.Disclosure of InterestNone Declared