bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study of price elasticity of demand and its application in first mile/last mile service collaboration between mass transit and ride sharing providers
Authors:   , Warapiankul Voragorn 
Published: September 2023

Since today, Bangkok faces the big pollution and low mobility. One main reason is Bangkok people tend to travel by automobiles instead of the transit. The main problem of Bangkok transit especially Bangkok metro is the low accessibility to travel to/from the transit nodes and between nodes or as called First Mile Last Mile problem. Moreover, Bangkok metro transit fare is claimed that is too expensive compared to the cost of living and minimum wages in Bangkok. This research aims to study the price elasticity of demand for Bangkok metro which is the indicator of fare demand management in Bangkok metro transit that is important to have the public opinion on the fare with their range of acceptable price. Following to analyse the approach for the collaboration between Bangkok metro transit and ride sharing providers, in order to find the solution to improve the First Mile Last Mile of Bangkok metro transit and the accepted service fare strategy. The research methods are surveying the Bangkok metro users for the accepted fare opinion and interviewing the metro operators and ride sharing providers for the collaborative approach with their fare strategies. The results show the metro routes which is operated by Bangkok Mass Transit System Public Company Limited (BTSC) is elastic to demand and should discount its current fare base on users opinion. While the metro routes which is operated by Bangkok Expressway and Metro Public Limited Company (BEM) is inelastic to demand that its current fare is already in the accepted range. Moreover, the Bangkok metro operator and ride sharing provider accept the collaborative approach that is able to gain the mutual benefit for the transport providers to increase its service demand and for the Bangkok people to increase the conveniences and decrease cost of travelling in their daily life.
An interlanguage study of L2 perception and production of english word stress by L1 Thai learners.
Authors:   , Jaiprasong Sawaros 
Published: September 2023

The aim of this study was to investigate L1 Thai learners’ English word stress perception and production of two different groups of English words: English words with different suffixes (suffixes affecting stress shift and neutral suffixes) and compound words (compound nouns and compound verbs). Three objectives were 1) to compare and contrast the perception of English word stress focusing on words, 2) to compare and contrast the production of English word stress focusing on words and 3) to investigate whether there is a relationship between L1 Thai learners’ perception and production of English word stress. Two groups of L1 Thai first-year undergraduate learners participated in this study: 30 L1 Thai beginners and 30 L1 Thai intermediate learners from Srinakharinwirot University. They completed two tasks: “Marking English Word Stress in Sentences” and “Reading English Word Stress in Sentences”. The results showed the L1 Thai intermediate learners significantly outperformed the L1 Thai beginners in both perception and production. Moreover, a relationship between the learners’ perception and production of English word stress was observed from the L1 Thai beginners and the L1 Thai intermediate learners. It was assumed that the problems of English stress assignment were caused by both interlingual and intralingual factors (Ellis, 2003; Haryani, 2016). Word stress placement rules in English and Thai differ substantially. Based on the Interlanguage Hypothesis, strategies of second language learning possibly have a negative impact on the problems (Selinker, 1972; Corder, 1999). The results contributed to second language acquisition and provided pedagogical implications for teaching and learning English pronunciation with respect to English word stress by L2 learners.
Pre-feasibility study on granite quarry for aggregate: a case study at Kanchanaburi province, Thailand
Authors:   , Ziyivang Bee 
Published: September 2023

This study aims to develop long term mine planning and design, equipment requirement calculation, and financial model analysis of mining and crushing plant. The ore reserve estimation and pit design carried out by using MineSight software (Ver. 9.50). A discounted cash flow model (DCF) and sensitivity analysis used to evaluate the financial project. Based on our study, the open-pit mining method was advisable for mine planning and design. Ore reserve estimated to 48.4 Mtons under the mining operation of 2.4 Mtos per year. The project time frame is 22 years which spends 21 years for operation and one year for preparation and development. The project required of 598 million baht for capital cost, spent 148 million baht for operating costs annually. The financial model indicated that NPV13.4% is 2,335 million baht, MIRR obtained 22.41%, and 1.6 years of payback period. The sensitivity analysis of the financial model shown that the most sensitive value was the aggregate price. For example, a 30% increase in aggregate price leading to raised NPV13.4% up from 2,335 million baht to 3,442 million baht. In contrast, a decrease of 30% in aggregate price resulted in NPV13.4% reduced by 53.62%.
Phospholipid- and gold-induced gelation of Thai silk fibroin
and its applications for cell and drug delivery
Authors:   , Laomeephol Chavee 
Published: September 2023

Recently, an in situ gelation, which is a rapid sol-to-gel transition under mild conditions, has been employed, allowing an entrapment of cells or substances in 3D structures as well as tailorable geometries and point-of-care uses. Silk fibroin (SF), a natural polymer from Bombyx mori silkworm cocoons, was chosen in this study as a substrate for the in situ hydrogel fabrication, due to self-assembly characteristic and a presence of modifiable functional groups. However, regenerated SF solution poses a slow gelation (several days or weeks) which is impractical for an in situ application. Therefore, a phospholipid, dimyristoyl glycerophosphoglycerol (DMPG), and a gold salt (Au3+) were introduced as chemical inducers to accelerate the gelation process of SF.

SF hydrogels induced by DMPG can be obtained within 10-40 min depending on the concentration of DMPG. Electrostatic and hydrophobic interactions were proposed as driving forces for inducing SF structural transition. Encapsulated L929 and NIH/3T3 fibroblasts in the hydrogel displayed a normal proliferation, confirming the cytocompatibility of DMPG-induced SF hydrogel. Subsequently, DMPG-based liposomes were prepared and loaded with an anticancer drug, curcumin. The liposomes can enhance loading amount and extend curcumin stability as well as induce the rapid gelation of SF. Curcumin released from liposome-SF hydrogels can inhibit the growth of cancer cells. When using the hydrogel as a substrate for cell culture, low cell survival was observed, possibly due to the combination of low cell attachment on SF and cytotoxicity of curcumin. Moreover, an addition of a gold salt (Au3+) in regenerated and thiolated SF solutions can accelerate the sol-to-gel transition. Dityrosine formation was proposed as an underlying mechanism of gelation for regenerated SF, while the formation of disulfide and Au-S bonds was proposed for thiolated SF. The obtained hydrogels exhibited good cytocompatibility with L929 fibroblasts.

In summary, the rapid gelation of SF can be achieved by the addition of DMPG or Au3+ salt. Different gelation mechanisms were proposed, and the obtained hydrogels showed the in vitro cytocompatibility, indicating the potential uses as a biomaterial for different biomedical applications.
Argonaute 4 promotes genomic methylation
Authors:   , Chalertpet Kanwalat 
Published: September 2023

RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic pathway in plants. Similar to genome and epigenome editing with the CRISPR-Cas9 system, RdDM is composed of a regulatory protein and a “guide” RNA (gRNA), which recruits the complex to specific genomic locations containing DNA sequences homologous to the RNA sequence. In humans, we found that Argonaute-4 (AGO4) colocalization has a strong correlation to promoter methylation of AGO4-binding genes. Here, we engineered cell-penetrating tagged oligoarginines (R9) tagged AGO4 (R9-AGO4) or xentry tagged AGO4 (X-AGO4) loaded with single guided-RNA (sgRNA) as a tool to specifically add methylation at genome locations where sgRNA is homologous to. We uncovered that only R9-AGO4-sgRNA complex can methylate both repetitive sequences (Alu and LINE-1) and unique copy gene (EML2 and CCNA1) while X-AGO4-sgRNA can penetrate into cells, but did not provide methylation change. The induction of methylation by R9-AGO4-LINE-1 or R9-AGO4-CCNA1 also contributes to down-regulation of their own gene expression. Moreover, R9-AGO4-LINE-1 can delay proliferation rate of transfected cells compared with their control counterparts. Therefore, our study is the first time reported that the engineered R9-AGO4 protein can be transfected to cells with sgRNA and can be used as an alternative tool for epigenomic editing at any specific genes or DNA sequences in humans.
Characteristics and mechanisms of coastal upwelling in the gulf of Thailand
Authors:   , Sripoonpan Pacharamon 
Published: September 2023

The characteristics and mechanisms of coastal upwelling in the Gulf of Thailand was investigated through 2 approaches; 1) Ekman transport upwelling index (UIET) and sea surface temperature upwelling index (UISST), and 2) Hydrodynamics model DELFT3D-FLOW under the influences of tide, spatially varying wind, water temperature, salinity and river discharge. The UIET indicated favorable upwelling conditions along the west coast of the GoT mostly during northeast monsoon in January and 1st inter-monsoon in March, while the favorable upwelling condition indicated by UISST was found along the east coast during southwest monsoon in August and 2nd inter-monsoon in October. The model expressed the favorable upwelling conditions along the west coast of the upper gulf and the west coast of Ca Mau Cape during northeast monsoon and southwest monsoon. Besides, the model results shown the upwelling with the obvious cooler coastal water along the west coast of the upper gulf and the central gulf and along the west coast of Ca Mau Cape during northeast monsoon and southwest monsoon, and with slightly cooler coastal water during 1st inter-monsoon in March and 2nd inter-monsoon in October. The coastal upwelling associated with UIET was different from UISST and the model simulation. The UIET indicated the wind-driven coastal upwelling directly connecting with directions of Ekman transport and wind. In contrast, the UISST was estimated using the satellite-observed sea surface temperature. Also, the upwelling found in the model simulation was generated using different forces, e.g., tide, wind, temperature, salinity, river discharge and heat. The tracked coastal upwelling in this study might be vital for fisheries resources managements and conservation, and to complete the knowledge of nutrient distributions in the Gulf of Thailand.
Pointwise dimension of archimedean copulas
Authors:   , Yanpaisan Noppawit 
Published: September 2023

In this thesis, we introduce the pointwise dimension of a bivariate copula C at (u,v) in [0, 1]2 via its C-volume. This quantity gives a broader view of probability mass distribution than the support of a copula, the smallest closed set on which the whole mass lies. We would like to study some fundamental properties of pointwise dimension, including the equality to pointwise exponent whenever both of them exist. After that, we investigate the behavior of the pointwise dimension of copulas constructed by various methods. In the last part, we compute the pointwise dimension of Archimedean copulas, an important class of copulas used widely in many branches.
Effects of non-albicans Candida species on biofilm formation and acidogenicity of dual-species biofilms and on cariogenic virulence gene expression of streptococcus mutans
Authors:   , Sansanoa Wirunphat 
Published: September 2023

Early childhood caries is a common oral disease found in children which could affect their general health. Streptococcus mutans is an important cariogenic pathogen since it possesses cariogenic properties, which are acid production, acid tolerance and biofilm formation. Recent studies showed that Candida albicans, which is frequently found together with S. mutans in plaques of children with dental caries, enhances cariogenicity. At the same time, increasing prevalence of non-albicans Candida species (NACs) in children and immune-compromised patients has been reported. Therefore, this study aims to investigate the effects of NACs when co-cultured with S. mutans on cariogenic properties and virulence gene expression of S. mutans. The results showed that C. albicans and NACs, especially Candida tropicalis, increased biofilm mass and cell viability of dual species biofilm, but did not increase acid production. For S. mutans gene expression, the genes related to exopolysaccharides synthesis (gtfBCD), sugar transportation (scrAB) and sugar utilization (pdhA and pfl) were up-regulated in dual species biofilm when co-culture with C. albicans, C. tropicalis and Candida krusei. In contrast, the expression levels of genes related to acid stress tolerance (atpD and fabM) in all dual-species biofilm were similar to S. mutans in single-species biofilm. In addition, the expression of genes involved in the signal transduction system (ciaRH) were upregulated in dual-species biofilms of S. mutans and C. albicans or NACs, except C. dubliniensis. In conclusion, the presence of NACs, especially C. tropicalis and C. krusei, could enhance cariogenic virulence factors of S. mutans similarly to C. albicans.
Multipole resonance probe measurement in plasma
Authors:   , Jampaiboon Natthapong 
Published: September 2023

Active plasma resonance spectroscopy (APRS) is one of the interesting methods which could avoid plasma contamination problem occurs in a conventional Langmuir probe measurement. It is because the probe conductors are covered by a dielectric material. The APRS probe can be of any shape. A multipole resonance probe is a hemisphere APRS probe since a sphere imposes the simplest way to find an analytical solution by solving the Laplace equation in the spherical coordinates with the azimuthal symmetry. In this study, the APRS probes in the hemisphere, microstrip, and parallel rod shapes were constructed. Plasma density was obtained by using the probe that is connected with a network analyzer to locate the match frequencies in the reflection coefficient spectrum. The match frequencies of different probe shapes were then calibrated with the plasma density obtained by Langmuir probe measurement. Our experiments showed that the constructed probes respond with the change in plasma. For the hemisphere probe, the results of the calibrated and the mathematically analyzed results were compared. Our study showed that the plasma density from the mathematical model is approximately the second order of magnitude away from that of the Langmuir probe.
Effects of gardenia jasminoides fruit extract on helicobacter pylori induced gastritis in vitro and in vivo studies
Authors:   , Noonak Nattida 
Published: September 2023

Helicobacter pylori (H. pylori) releases virulence factors to gastric epithelial cells causing an imbalance between aggressive factors and protective factors leading to gastritis inflammation. Gardenia jasminoides (G. jasminoides) fruit extract contains geniposide as a major bioactive compound that possesses anti-inflammatory effects. The present study aimed to investigate the effects of G. jasminoides fruit extract on gastric inflammation and protective mechanisms in H. pylori-induced gastritis. In an in vitro experiment, we demonstrated that G. jasminoides fruit extract could inhibit growth of H. pylori using disk diffusion method. The result showed that the inhibition zone was observed at geniposide ≥ 0.16 mg/disc. In an in vivo experiment, rats were divided into 5 groups (n=7 each): 1) control, 2) H. pylori; rats were inoculated with H. pylori (108-1010 CFU/mL) 1 mL twice daily for 3 consecutive days, 3) Hp+gen8, 4) Hp+gen16, 5) Hp+gen32; rats were inoculated with H. pylori and two weeks later, treated with G. jasminoides fruit extract suspended in 5% methylcellulose, received G. jasminoides fruit extract at the dose of 98.52, 197.04, and 394.09 mg/kg, which contained geniposide at the dose of 8, 16 and 32 mg/kg, respectively once daily for 1 week. Gastric tissues were collected for gastric histopathology and immunohistochemistry (IHC) staining for epidermal growth factor (EGF). Serum samples were collected for interleukin-17 (IL-17), interleukin-33 (IL-33), and prostaglandin E2 (PGE2) analyses using ELISA. The results showed that rats in H. pylori group had increased IL-17, IL-33, EGF and decreased PGE2 levels and developed gastric inflammation on histology. Treatment with geniposide in G. jasminoides fruit extract could decrease IL-17, IL-33, EGF, and increase PGE2 levels. In addition, G. jasminoides fruit extract improved gastric histopathology. These findings suggested that G. jasminoides fruit extract attenuated H. pylori-induced gastritis by inhibiting bacterial growth, reducing inflammation, and enhancing protective mechanisms.
Knowledge and attitude on practice of iron deficiency anemia prevention among high school female students in Banjarmasin City, Indonesia: a mixed method study
Authors:   , Munira Lafi 
Published: September 2023

Based on the Indonesia National Basic Health Survey in 2018, the prevalence of anemia in young women was 48.9%, along with the major proportions of anemia in the age group of 15-24 years. This study aimed to examine the influence of knowledge and attitude on iron deficiency anemia prevention practice and to find out the reasons for not practicing anemia prevention among female high school students in Banjarmasin, Indonesia. The mixed-method study with a quantitative study: cross-sectional survey study (April 2020) was conducted through an online survey among 359 female students (15-18 years old) and qualitative study: focus group discussion and in-depth interview (April-May 2020) were conducted through tele-interview via video call among teacher and health officers. Purposive sampling was used to select three high schools with a high prevalence of anemia in Banjarmasin, Indonesia. Data analysis for the quantitative study was used binary logistic regression and for qualitative study were used a combination of content analysis and thematic analysis. Results: A total of 359 female students participated in the study with the age range from 15 to 18 years old. The results showed 166 (46.2%) of female students had poor practice, along with 152 (42.3%) poor attitude level and 175 (48.7%) poor knowledge level towards iron deficiency anemia prevention. The study also indicated that age group (17-18 years old) OR (95%CI): 1.60 (1.03, 2.50) p = 0.039, types of school l OR (95%CI): 0.55 (0.34, 0.90) p = 0.017, knowledge OR (95%CI): 1.07 (1.01, 1.13) p = 0.031 were significant predictors of practicing iron deficiency anemia prevention. Top 3 reasons for not practicing anemia prevention among students were 1) Feeling nausea after taking iron tablets (32%); 2) Don’t like the smell and color of iron tablets (21.4%); 3) Don’t know the benefit of practice anemia prevention (18.9%). From focus group discussion findings found that lack of information given and lack of the duration of information given linked to lack of knowledge among female students. Main reasons for not practicing anemia prevention among female students were related to the dislike of iron tablets and lack of knowledge due to ineffective anemia education program. Therefore, anemia prevention programs should be improved for increasing the knowledge of students towards the benefit of anemia prevention practice and iron tablets compliance.
Effectiveness of the self static stretching strengthening program on physical performances in market vendors: a Quasi-experimental study
Authors:   , Cetthakrikul Salila 
Published: September 2023

Introduction: Work-related musculoskeletal disorders (WRMDs) often occurs within the market vendor group. This study design is a Self-Static Stretching and Strengthening program for market vendors for reducing and/or preventing WRMDs. Objective: To determine the effectiveness of the Self-Static Stretching and Strengthening program (SSS program) compared with ergonomic knowledge on physical performances in market vendors. Methods: This study design was a quasi-experimental study with the control group. Base on convenience, the Samyan market was placed into the intervention group and the Ortorkor market was placed into the control group. The market vendors who volunteered were asked to complete the questionnaire and were measured muscle pain, muscle flexibility, and grip strength. As well, the market vendors who met the criteria were recruited to this study. The market vendors in the intervention group performed SSS program with physical therapists 3 times a week for 4 weeks and they were asked to perform this program by themselves for 6 months. Both groups were assessed at 5-time points. Repeated measures ANCOVA was used for determining the effects of SSS program on physical performances. Result: After final implementation, there were 131 participants attended the study (intervention group = 56, control group =75). There was no statistically significant difference in participant characteristics between both groups. After the intervention program was completed, there were significant differences in the degree of pain between both groups in the lower back area and at the left leg area at post-intervention and 1-month follow up (p<0.05). There were significant differences in muscle flexibility between groups at post-intervention and 1-month, 3-months and 6 months follow up (p<0.05). Conclusion: The Self-Static Stretching and Strengthening program has effective for reducing muscle pain at the lower back and legs and improving muscle flexibility when compared between both groups. The results of this study may be generalized to market vendors in other markets within a similar context.