bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors affecting citizens’ intention to use e-government services: assessing the mediating effect of perceived usefulness and ease of use
Authors: Zubir Muhammad Hafiz Hariz , Abdul Latip Muhammad Safuan 
Published: August 2023

Purpose
This paper aims to examine how information and communication technology (ICT) coordination, information reliability, social pressure, perceived usefulness and perceived ease of use affect citizens’ intentions to use e-government services.

Design/methodology/approach
The study is a quantitative type of study conducted through a causal study design. Noncontrived and cross-sectional methods were used, targeting Malaysian citizens who were 18 years of age or older. Due to an inaccessible sample frame, convenience sampling was used. After cleaning and removing necessary outliers, the final data set used for hypothesis testing consisted of 323 responses, which is considered sufficient as the study required a minimum sample size of 220.

Findings
A study has found that social pressure, perceived ease of use and perceived usefulness positively affect people’s intention to use e-government services. The impact of social pressure is influenced by perceived usefulness and ease of use, suggesting that government agencies can encourage usage by improving perceived usefulness and leveraging social pressure. The study emphasizes the significance of perceived usefulness and social pressure in promoting adoption. To enhance the user experience, agencies can use targeted marketing, improve service quality, collaborate with communities and develop mobile applications.

Originality/value
The study underscores the importance of examining the relationship between perceived usefulness, ease of use and the popularity of e-government services while emphasizing the need to comprehend the impact of ICT coordination, information reliability and social pressure on the adoption of e-government applications in developing countries.
Implementing physical activity in nursing homes: a qualitative exploration of Turkish health care staff’ experiences
Authors: Arıkan Dönmez Ayşe , Aslan Funda 
Published: August 2023

Purpose
Implementing physical activity in nursing homes (NHs) can improve functional capacity, quality of life and well-being and even control symptoms associated with chronic diseases in elderly people. Taking into consideration the increasing in number of NHs in Türkiye, it is obvious that this matter should be handled. The purpose of this study is to explore health-care staff’s perspectives on implementing physical activity in NHs.

Design/methodology/approach
A generic, qualitative study using face-to-face semi-structured interviews was conducted among 25 health-care staff. A theoretical sampling strategy was used to inform data collection. Data were analyzed using a thematic analysis method.

Findings
Three main themes and seven sub-themes were generated from health-care staff’s narratives of implementing physical activity. Main themes were the lack of knowledge about physical activity, negative mindset and organizational requirements. Implementing physical activity in NHs contributes to a better quality of life for the residents and the protection and improvement of their health. However, a lack of knowledge, negative perceptions of both health-care staff and administrators about physical activity and the organizational requirement were recognized.

Originality/value
Findings from this study will enable administrators to recognize the potential challenges and make informed decisions to implement physical activity programs for NH residents from health-care staff’s perspectives who are working with elderly people.
Exploring machine learning methods for predicting systemic lupus erythematosus with herpes
Authors: Wang Da‐Cheng , Tang Yang‐Yang , He Cheng‐Song , Fu Lu , Liu Xiao‐Yan , Xu Wang‐Dong 
Published: August 2023

AbstractObjectivesTo investigate whether machine learning, which is widely used in disease prediction and diagnosis based on demographic data and serological markers, can predict herpes occurrence in patients with systemic lupus erythematosus (SLE).MethodsA total of 286 SLE patients were included in this study, including 200 SLE patients without herpes and 86 SLE patients with herpes. SLE patients were randomly divided into a training group and a test group, and 18 demographic characteristics and serological indicators were compared between the two groups.ResultsWe selected basophil, monocyte, white blood cell, age, immunoglobulin E, SLE Disease Activity Index, complement 4, neutrophil, and immunoglobulin G as the basic features of modeling. A random forest model had the best performance, but logistic and decision tree analyses had better clinical decision‐making benefits. Random forest had a good consistency between feature importance judgment and feature selection. The 10‐fold cross‐validation showed the optimization of five model parameters.ConclusionThe random forest model may be an excellently performing model, which may help clinicians to identify SLE patients whose disease is complicated by herpes early.
Association between substance‐induced psychosis and suicide attempt: A Danish nation‐wide register‐based study
Authors: Munch Solvejg Dam , Madsen Trine , Nordentoft Merete , Erlangsen Annette , Hjorthøj Carsten 
Published: August 2023

AbstractBackground and aimsSubstance‐induced psychosis has previously been linked to an excess risk of suicide; however, the association between substance‐induced psychosis and suicide attempt has hitherto not been investigated. We investigated whether substance‐induced psychosis was associated with a higher risk of subsequent suicide attempt.DesignNation‐wide prospective register‐based cohort study.SettingDenmark.ParticipantsAll people living in Denmark aged 13 years or more during 1995 to 2017.MeasurementsSubstance‐induced psychosis and suicide attempts were identified through hospital records as ICD‐10 codes.FindingsA total of 8900 (78.8% males) individuals were diagnosed with a substance‐induced psychosis, and 740 of these had a suicide attempt during follow‐up. People with a substance‐induced psychosis had a higher risk of a subsequent suicide attempt [hazard ratio (HR) = 13.4, 95% confidence interval (CI) = 12.4–14.4] when compared with the general population. The highest hazard ratios were found for psychosis induced by opioids (HR = 26.4, 95% CI = 18.2–38.2); alcohol (HR = 17.7, 95% CI = 15.2–20.6); sedatives (HR = 17.2, 95% CI = 8.9–33.0); and cocaine (HR = 15.6, 95% CI = 10.7–22.8), while cannabis‐induced psychosis was linked to an HR of 8.9 (95% CI = 7.7–10.3). Approximately 15% of patients with substance‐induced psychosis had had a suicide attempt within 20 years of their substance‐induced psychosis diagnosis.ConclusionsIn Denmark, substance‐induced psychosis appears to be strongly associated with subsequent suicide attempt, underscoring the importance of attention and better follow‐up for this patient group.
Vital signs and medical emergency response (MER) activation predict in‐hospital mortality in general surgery patients: a study of 15 969 admissions
Authors: Kovoor Joshua G. , Bacchi Stephen , Stretton Brandon , Gupta Aashray K. , Lam Lydia , Jiang Melinda , Lee Shane , To Minh‐Son , Ovenden Christopher D. , Hewitt Joseph N. , Goh Rudy , Gluck Samuel , Reid Jessica L. , Hugh Thomas J. , Dobbins Christopher , Padbury Robert T. , Hewett Peter J. , Trochsler Markus I. , Flabouris Arthas , Maddern Guy J. 
Published: August 2023

AbstractBackgroundThe applicability of the vital signs prompting medical emergency response (MER) activation has not previously been examined specifically in a large general surgical cohort. This study aimed to characterize the distribution, and predictive performance, of four vital signs selected based on Australian guidelines (oxygen saturation, respiratory rate, systolic blood pressure and heart rate); with those of the MER activation criteria.MethodsA retrospective cohort study was conducted including patients admitted under general surgical services of two hospitals in South Australia over 2 years. Likelihood ratios for patients meeting MER activation criteria, or a vital sign in the most extreme 1% for general surgery inpatients (<0.5th percentile or > 99.5th percentile), were calculated to predict in‐hospital mortality.Results15 969 inpatient admissions were included comprising 2 254 617 total vital sign observations. The 0.5th and 99.5th centile for heart rate was 48 and 133, systolic blood pressure 85 and 184, respiratory rate 10 and 31, and oxygen saturations 89% and 100%, respectively. MER activation criteria with the highest positive likelihood ratio for in‐hospital mortality were heart rate ≤ 39 (37.65, 95% CI 27.71–49.51), respiratory rate ≥ 31 (15.79, 95% CI 12.82–19.07), and respiratory rate ≤ 7 (10.53, 95% CI 6.79–14.84). These MER activation criteria likelihood ratios were similar to those derived when applying a threshold of the most extreme 1% of vital signs.ConclusionsThis study demonstrated that vital signs within Australian guidelines, and escalation to MER activation, appropriately predict in‐hospital mortality in a large cohort of patients admitted to general surgical services in South Australia.
Repeated robotic pancreatectomy for recurrent pancreatic metastasis of mesenchymal chondrosarcoma: A case report
Authors: Hayashida Sayuri , Ikenaga Naoki , Nakata Kohei , Nakamura So , Abe Toshiya , Ideno Noboru , Endo Makoto , Noguchi Shoko , Oda Yoshinao , Nakamura Masafumi 
Published: August 2023

AbstractMesenchymal chondrosarcoma is a rare subset of sarcomas accounting for 3%–10% of all cases of chondrosarcomas. Radical resection is the only curative strategy, even in patients with metastatic tumors. However, data regarding treatment strategies remain limited owing to the small number of cases. Herein, we report a patient who underwent repeated robotic pancreatectomy for recurrent pancreatic metastasis originating from extraskeletal mesenchymal chondrosarcoma of the pelvis. First, robotic pancreaticoduodenectomy with a reconstruction of pancreaticogastrostomy was performed for synchronous pancreatic metastasis 5 months after the primary resection of mesenchymal chondrosarcoma. Ten months after robotic pancreaticoduodenectomy, tumor recurrence was observed at the tail end of the pancreas, which was removed by reperforming robotic distal pancreatectomy. Given the precise tissue manipulation that can be achieved with robotic articulated forceps, the peripheral splenic artery and pancreas were easily isolated and divided in close proximity to the tumor. The central part of the pancreas was preserved. Robotic surgery allowed safe and effective resection of the reconstructed remnant pancreas. The patient survived for 28 months after primary tumor resection. Repeated pancreatectomy with minimally invasive techniques is a feasible and curative treatment for metastatic mesenchymal chondrosarcoma.
Usefulness of real‐time navigation using intraoperative ultrasonography for rectal cancer resection
Authors: Otani Kensuke , Kiyomatsu Tomomichi , Ishimaru Kazuhiro , Kataoka Atsuko , Hayashi Yuki , Gohda Yoshimasa 
Published: August 2023

AbstractIntroductionAt our institute, we usually perform robot‐assisted surgery for rectal cancer as minimally invasive surgery. It is necessary to recognize the tumor edge accurately when deciding where to place the distal cutting line of the rectum. In this article, with video presentation, we demonstrate the usefulness of intraoperative sonography (IOUS) for detecting the rectal tumor site in robotic surgery. This is the first report to discuss the IOUS image of rectal cancer.Materials and Surgical TechniqueAfter mobilization of the rectum in robotic procedure, the rectum should be straightened. Drop the laparoscopic ultrasonography probe through the 12‐mm assistant port and place it at the anterior wall of the rectum. By presenting operative and ultrasound findings simultaneously on a single monitor, the operator can recognize the tumor location accurately and decide on the cutting line. We report three cases in the supporting video presentation.DiscussionRectal tumors can be detected by IOUS, and this modality is effective for determining the cutting line of the rectum. Real‐time navigation by IOUS can be performed noninvasively and easily, so it is expected to be helpful in cases of robotic rectal cancer resection.
Effect of food and polymorphisms in SLCO2B1, CYP3A4 and UGT1A4 on pharmacokinetics of abiraterone and its metabolites in Chinese volunteers
Authors: Hu Yixin , Wu Jianyuan , Cheng Bingyu , You Rongli , Yin Xueyan , Chen Guiying , Yang Ling , Zhang Yang , Si Luqin , Jiang Hongliang , Zhang Yongjun , Huang Jianying , Huang Jiangeng 
Published: August 2023

AimsAbiraterone acetate, a prodrug of abiraterone (ABI), provides an efficient therapeutic option for metastatic castration‐resistant prostate cancer patients. ABI undergoes extensive metabolism in vivo and is transformed into active metabolites Δ4‐abiraterone and 3‐keto‐5α‐abiraterone as well as inactive metabolites abiraterone sulfate and abiraterone N‐oxide sulfate. We aimed to examine the effect of polymorphisms in SLCO2B1, CYP3A4 and UGT1A4 on the pharmacokinetics of ABI and its metabolites.MethodsIn this study, 81 healthy Chinese subjects were enrolled and divided into 2 groups for fasted (n = 45) and fed (n = 36) studies. Plasma samples were collected after administering a 250 mg abiraterone acetate tablet followed by liquid chromatography–tandem mass spectrometry analysis. Genotyping was performed on a MassARRAY system. The association between SLCO2B1, CYP3A4, UGT1A4 genotype and pharmacokinetic parameters of ABI and its metabolites was assessed.ResultsFood effect study demonstrated high fat meal remarkedly increased systemic exposure of ABI and its metabolites. The geometric mean ratio and 90% confidence interval of area under the plasma concentration–time curve from time 0 to the time of the last quantifiable concentration (AUC0‐t) and maximum plasma concentration (Cmax) of ABI in fed state vs. fasted state were 351.64% (286.86%–431.04%) and 478.45% (390.01%–586.94%), respectively, while the corresponding results were ranging from 145.11% to 269.42% and 150.10% to 478.45% for AUC0‐t and Cmax of ABI metabolites in fed state vs. fasted state, respectively. The SLCO2B1 rs1077858 had a significant influence on AUC0‐t and Cmax, while 7 other SLCO2B1 variants prolonged half‐life of ABI under both fasted and fed conditions. As for ABI metabolites, the systemic exposure of Δ4‐abiraterone, abiraterone sulfate and abiraterone N‐oxide sulfate as well as the elimination of 3‐keto‐5α‐abiraterone were significantly affected by SLCO2B1 polymorphisms. Polymorphisms in CYP3A4 and UGT1A4 did not significantly affect pharmacokinetics of ABI and its metabolites.ConclusionPolymorphisms in SLCO2B1 were significantly related to the pharmacokinetic variability of ABI and its metabolites under both fasted and fed conditions.
Risk factors impacting the survival of implants replaced following failure: A retrospective study
Authors: Lee Dongseob , Ko Young‐Chang , Seol Yang‐Jo , Koo Ki‐Tae , Lee Yong‐Moo , Lee Jungwon 
Published: August 2023

AbstractAimThis study aimed to investigate factors influencing the survival of replaced dental implants.Materials and MethodsCharts from 2005 to 2021 were reviewed. Replaced implants after removal for the first time were identified. Depending on their survival, the replaced group was divided into the surviving and second‐removal groups. Risk factors affecting survival of replaced implants were evaluated considering clustering of multiple implants within patients.ResultsThe present study included 464 replaced implants of 370 patients, of which 429 and 35 implants were categorized into the surviving group and the second‐removal group. The 5‐year survival rate was 90.2 ± 0.18% in replaced implants at sites with a periodontitis history and 97.0 ± 0.15% at sites without a periodontitis history (p = 0.008). The 5‐year survival rate was 89.1 ± 0.27% in replaced implants with guided bone regeneration (GBR) at first implant placement and 93.9 ± 0.14% at non‐GBR (p = 0.032). The 5‐year survival rate was 97.6 ± 0.13% in replaced implants with GBR and 90.3 ± 0.17% in replaced implants without GBR (p = 0.026). In the multivariable analysis adjusted for clinical variables, periodontitis history (adjusted hazard ratio [aHR] = 3.417; 95% confidence interval [CI] = 1.161–10.055), GBR at first implant placement (aHR = 2.152; 95% CI = 1.052–4.397) and non‐GBR at primary implant replacement (aHR = 0.262; 95% CI = 0.088–0.778) were identified as independent risk factors for second implant removal.ConclusionsPeriodontitis history, GBR at first implant placement and non‐GBR at primary implant replacement were identified as risk factors affecting the survival of replaced implants.
Bibliometric analysis of the 100 most cited articles on bone grafting in dentistry
Authors: dos Anjos Lucas Menezes , Rocha Aurélio de Oliveira , Magrin Gabriel Leonardo , Kammer Pedro Vitali , Benfatti Cesar Augusto Magalhães , Matias de Souza Júlio César , Sanz Mariano , Henriques Bruno Alexandre Pacheco de Castro 
Published: August 2023

AbstractAimThis bibliometric study analyzed the characteristics of the 100 most cited articles on bone grafts in dentistry.Materials and MethodsA database search was performed on the Web of Science Core Collection using a specific search strategy. Scopus and Google Scholar were also consulted for citation comparisons. Data extracted included: title, citation metrics, publication year, journal, study design, graft material, surgical technique, authors, institution, and country. Bibliometric networks were generated using VOSviewer.ResultsThe identified articles were published between 1991 and 2019. Citation counts ranged from 120 to 1161 (mean: 240, 30). Clinical Oral Implants Research was the most cited journal (5175 citations; 25/100). Xenogeneic bone graft material was the most frequently used (5130 citations; 22/100). Europe had 62 articles (14,604 citations), and the United States was the most prominent country (5209 citations; 22/100). The University of Bern had the highest number of citations (2565 citations; 13/100), with Buser D as the author with the largest number of articles (2648 citations; 12/100).ConclusionThis study shows the scientific progress on bone grafts in dentistry. The use of xenogeneic grafts for horizontal and/or vertical ridge augmentation was the most prominent trend.
Learnings from a prison‐based drug treatment program on planning for release: A qualitative study
Authors: D’Souza Bebe , Butler Tony , Shakeshaft Anthony , Calder Ivan , Conigrave Katherine , Doyle Michael 
Published: August 2023

AbstractIntroductionPrison‐based drug and alcohol group treatment programs operate in all Australian jurisdictions. With more than two‐thirds of people in prison having a history of substance use prior to incarceration, such programs are needed. There have been few published papers on the impact of attending group treatment programs in Australian prisons, and the research published to date has been predominately quantitative. We aim to report the experiences of males in prison who completed and those who did not complete a group‐based drug and alcohol program, to gain insight into their strategies for reducing harm from drug and alcohol post‐release.MethodsQualitative thematic analysis of in‐depth interviews with 12 males who completed or were about to complete and 10 males who discontinued a prison‐based group drug and alcohol treatment program.ResultsProgram completers were more likely to have well‐developed plans to reduce drug and alcohol harms and maintain abstinence upon return to the community, which included creating healthier social networks. They also showed stronger insights into the factors that led to offending. Those who did not complete the drug and alcohol program appeared to rely on self‐will as the main way to reduce drug and alcohol harms, with less awareness of options for support services to reduce or stop drug and alcohol use.Discussion and ConclusionsPrison‐based drug and alcohol program engagement imparted useful information for program completers. Controlled trials are needed to examine whether such differences equate to improved outcomes after release.
Impaired erythropoietin‐producing hepatocellular B receptors signaling in the prefrontal cortex and hippocampus following maternal immune activation in male rats
Authors: Shao Yiqian , Cai Yaqi , Chen Tengfei , Hao Keke , Luo Binbin , Wang Xiujuan , Guo Weiyun , Su Xi , Lv Luxian , Yang Yongfeng , Li Wenqiang 
Published: August 2023

AbstractAn environmental risk factor for schizophrenia (SZ) is maternal infection, which exerts longstanding effects on the neurodevelopment of offspring. Accumulating evidence suggests that synaptic disturbances may contribute to the pathology of the disease, but the underlying molecular mechanisms remain poorly understood. Erythropoietin‐producing hepatocellular B (EphB) receptor signaling plays an important role in synaptic plasticity by regulating the formation and maturation of dendritic spines and regulating excitatory neurotransmission. We examined whether EphB receptors and downstream associated proteins are susceptible to environmental risk factors implicated in the etiology of synaptic disturbances in SZ. Using an established rodent model, which closely imitates the characteristics of SZ, we observed the behavioral performance and synaptic structure of male offspring in adolescence and early adulthood. We then analyzed the expression of EphB receptors and associated proteins in the prefrontal cortex and hippocampus. Maternal immune activation offspring showed significantly progressive cognitive impairment and pre‐pulse inhibition deficits together with an increase in the expression of EphB2 receptors and NMDA receptor subunits. We also found changes in EphB receptor downstream signaling, in particular, a decrease in phospho‐cofilin levels which may explain the reduced dendritic spine density. Besides, we found that the AMPA glutamate, another glutamate ionic receptor associated with cofilin, decreased significantly in maternal immune activation offspring. Thus, alterations in EphB signaling induced by immune activation during pregnancy may underlie disruptions in synaptic plasticity and function in the prefrontal cortex and hippocampus associated with behavioral and cognitive impairment. These findings may provide insight into the mechanisms underlying SZ.
VOICING VULNERABILITY: MEDIATING VIOLENCE, VICTIMISATION AND FEMALE SUBJECTIVITY IN NORA GOMRINGER'S MONSTER POETRY*
Authors: Märten Annegret 
Published: August 2023

ABSTRACTThis chapter examines poetic works by the Swiss‐German performance poet Nora‐Eugenie Gomringer that draw on monsters as a conceptual lens to engage with experiences of vulnerable subjects, that is, those that have experienced harm or violence or are considered especially susceptible to these risks. The anthology Monster Morbus Moden (2013–17), with its initial collection Monster Poems (2013), reflects poetically on how female subjects and their bodies, which are conventionally represented as weak, are simultaneously and paradoxically considered dangerously non‐normative and in need of policing. Gomringer explores how this paradox emerges from the interplay of textual and media surfaces, institutional logic and intersubjective power imbalances. The author employs an experimental mix of intertextual, intermedial and performative strategies that draws attention to the embodied and culturally iterative nature of such subject constructions. Putting emphasis on visualising and voicing victimisation, these works can be seen to probe to what extent a monstrous poeticisation of such experiences might shift stereotyping scopic regimes that produce the conditions for the widespread sexual violence against women or curtail reproductive freedoms. This experimentation, this article argues, seeks to establish awareness around the potential mobility of the concept of ‘vulnerability’ that has also been raised in recent feminist discussions.