bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abnormal sleep blood pressure patterns are associated with diffusion tensor imaging along perivascular spaces index in cognitively impaired individuals
Authors: Buongiorno Mariateresa , Sánchez-Benavides Gonzalo , Caruana Giovanni , Elias-Mas Andrea , Artero Cristina , Cullell Natalia , Delgado Pilar , Giraldo Darly Milena , Marzal-Espí Clara , Grau-Rivera Oriol , de la Sierra Alejandro , Delgado-Sanchez Ariane , Ray Nicola J. , Krupinski Jerzy 
Published: February 2025

AbstractBlood pressure (BP) physiologically dips during sleep, and lack of dipping associates with adverse health outcomes and cognitive decline. Vascular pulsatility is the main driver of glymphatic cerebrospinal fluid transport, which removes metabolic waste products from the brain during sleep. We hypothesized that abnormal sleep BP patterns may affect glymphatic system health, and that this relationship may result in lower diffusion tensor imaging along perivascular spaces (DTI-ALPS) indices, a proposed neuroimaging index of glymphatic health. Twenty-one participants with mild-to-moderate cognitive impairment underwent 24-hour ambulatory BP monitoring, DTI-MRI and Alzheimer’s disease (AD) biomarker studies. Eight participants were classified as dippers (≥10%) and 13 as non-dippers (<10%), using sleep/awake systolic BP percentage of change. We found that non-dippers had lower DTI-ALPS even when adjusted by age and clinical stage (p=0.013). Stiffness measures (pulse wave velocity) were negatively correlated to DTI-ALPS (r=-0.5), but the association disappeared when adjusted by age. Positive AD biomarkers were more frequent in individuals who were classified as non-dippers of both systolic and diastolic BP, as compared to systolic and diastolic dippers (p=0.041). Our findings suggest that deviations of the physiological dipping sleep BP pattern may relate to poorer glymphatic function and increased AD pathology.
Cdk1 and PP2A constitute a molecular switch controlling orderly degradation of atypical E2Fs
Authors: Nachum-Raines Sapir , Gamliel Noy , Wasserman Danit , Qassem Nasrin , Sher Inbal , Guez-Haddad Julia , Emanuele Michael J , Chill Jordan H , Tzur Amit 
Published: February 2025

AbstractDynamic oscillations in the phosphorylation and ubiquitination of key proliferative regulators are defining features of the eukaryotic cell cycle. Resetting the cell cycle at the mitosis-to-G1 transition requires activation of the E3 ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C), which ensures cell cycle irreversibility by targeting dozens of substrates for degradation, safeguarding genome integrity. However, the overall coupling of substrate phosphorylation with target recognition and degradation by the APC/C remains relatively unexplored. As a paradigm for further defining these rules, we focused on E2F7 and E2F8 – atypical E2F-family proteins that coordinate cell cycle gene expression by restraining the pro-proliferative transcriptional activity of E2F1. Leveraging complementary cell and cell-free systems, we demonstrate that flexible domains in the amino-termini of E2F7 and E2F8 contain APC/C recognition motifs adjacent to critical Thr residues, whose phosphorylation by Cdk1 is rate limiting for degradation. The removal of this phosphorylation by PP2A phosphatase serves as a molecular switch, coupling the degradation of E2F7 and E2F8 to the G1 phase, coinciding with the rise of E2F1. Collectively, these findings highlight a critical role for Cdk1-PP2A signaling in controlling the orderly degradation of APC/C substrates, ensuring precisely timed assembly of the transcriptional infrastructure that coordinates cell cycle commitment and progression.
Molecular mechanisms of recruitment, function and regulation of UPF1 in histone mRNA decay
Authors: de Amorim Alexandrina Machado , Xue Guangpu , Dittmers Theresa , He Wenxia , Lewandowski Sarah , Perez-Borrajero Cecilia , Bethmann Juliane , Mateva Nevena , Krage Clemens , Nandana Vidhyadhar , Hennig Janosch , Urlaub Henning , Marzluff William F. , Chakrabarti Sutapa 
Published: February 2025

AbstractAnimal replication-dependent histone mRNAs end in a conserved stem loop (SL) instead of the canonical poly(A) tail present in all other eukaryotic mRNAs. Degradation of the histone SL at the end of the S-phase is initiated by the stem-loop binding protein SLBP and its interplay with the RNA helicase UPF1 and the exoribonuclease 3’hExo. We report direct interactions between SLBP and UPF1 and show that the unstructured SLBP N-terminus wraps around the UPF1 helicase core, contacting it at multiple sites. Although binding of SLBP to UPF1 impedes unwinding activity, it is critical for efficient histone mRNA decay in cells, as unwinding of the SL facilitates degradation by 3’hExo. Here we show that the UPF1-activator, UPF2, binds 3’hExo, and that UPF2-mediated activation of UPF1 overrides the inhibitory effect of SLBP. Our results highlight the intricate network of UPF1-centric protein-protein and protein/RNA interactions that fine-tunes its unwinding activity and orchestrates timely and efficient degradation of histone mRNA.
Replisomes restrict SMC-mediated DNA-loop extrusionin vivo
Authors: Liao Qin , Brandão Hugo B. , Ren Zhongqing , Wang Xindan 
Published: February 2025

AbstractStructural maintenance of chromosomes (SMC) complexes organize genomes by extruding DNA loops, while replisomes duplicate entire chromosomes. These essential molecular machines must collide frequently in every cell cycle, yet how such collisions are resolvedin vivoremains poorly understood. Taking advantage of the ability to load SMC complexes at defined sites in theBacillus subtilisgenome, we engineered head-on and head-to-tail collisions between SMC complexes and the replisome. Replisome progression was monitored by marker frequency analysis, and SMC translocation was monitored by time-resolved ChIP-seq and Hi-C. We found that SMC complexes do not impede replisome progression. By contrast, replisomes restrict SMC translocation regardless of collision orientations. Combining experimental data with simulations, we determined that SMC complexes are blocked by the replisome and then released from the chromosome. Occasionally, SMC complexes can bypass the replisome and continue translocating. Our findings establish that the replisome is a barrier to SMC-mediated DNA-loop extrusionin vivo, with implications for processes such as chromosome segregation, DNA repair, and gene regulation that require dynamic chromosome organization in all organisms.
Latitudinal phylogenetic and diversity gradients are explained by a tropical-temperate transitional region
Authors: Lerner David , Weir Jason T. , Klein Tamir , Greenbaum Gili 
Published: February 2025

AbstractThe distribution of ecological and evolutionary forces throughout space bring about the patterning of biodiversity. In large geographical areas, this causes the regionalization of biodiversity into structured units known as bioregions. In order to understand how such patterns emerge, a clear delineation of bioregions is required. We use tree species as model taxa in order to analyze the global distribution of biodiversity and understand how latitudinal gradients of biodiversity, specifically the latitudinal phylogenetic and diveristy gradients are formed. By compiling an extensive dataset of tree species distributions and their phylogenetic relationships, we use a data-driven approach to delineate global bioregions of similar evolutionary histories, termed phyloregions. Our analysis reveals the presence of a region between the tropical and temperate regions, coined ‘bridge’ phylore-gion, with a unique evolutionary composition and characteristically weaker association to climatic and environmental parameters. Through simulations, we show that the pres-ence of latitudinal phylogenetic and diversity gradients are much more likely to emerge in the presence of an independent ecological region between tropical and temperate regions, suggesting that its role as a stepping-stone in colonization of species between distinct climatic zones has shaped latitudinal gradients. This study highlights that accurate de-lineation of evolutionary structures of biodiversity can reveal previously cryptic regions with fundamental evolutionary roles in the formation of biodiveristy patterns.1Significance StatementBiodiversity patterns are shaped by geography, forming distinctive units known as bioregions. At global scales there are important gradients in terms of species diversity and phylogenetic relations that are well documented, but the underlying processes that generate them are unclear. We comprised an extensive dataset of tree species distributions and phylogeny, and identified the bioregions from the dataset. We analyzed the diversity and the phylogenetic gradients and identified a previously cryptic bioregion between tropical and temperate zones. Though less climatically distinct, we show through simulations that the presence of this transition zone better explains latitudinal biodiversity patterns. Our findings refine the global dispersal dynamics of species between tropical and temperate regions and highlight the role of this intermediate region in shaping global biodiversity patterns.
Dual origin in the temperature dependence of the coupling parameter for the strange metal state in heavily overdoped cuprate superconductor
Authors: Miyai Yudai , Ideta Shin-ichiro , Arita Masashi , Tanaka Kiyohisa , Oda Migaku , Kurosawa Tohru , Shimada Kenya 
Published: February 2025

The real and imaginary parts of the self-energy in the wide energy range have been evaluated from high-resolution angle-resolved photoemission spectroscopy (ARPES) spectra of a heavily overdoped single-layer cuprate superconductor (Bi,Pb)2Sr2CuO6+δ in the normal state. The real part of the self-energy has the zero-point crossing at −0.6 eV, where the lifetime broadening takes maximum and the ARPES spectral intensity is significantly suppressed forming a high-energy anomaly (HEA). The self-energy part responsible for the HEA is almost temperature independent and the coupling parameter is λHEA∼1 at 300 K, indicating strongly correlated nature of the strange metal state. Meanwhile, the self-energy part responsible for the low-energy kink (LEK) near the Fermi level shows significant temperature dependence: it is λLEK∼0.1 at 300 K but enhances steeply below ∼150K up to λLEK∼0.8, leading to the total coupling strength of λtot=λHEA+λLEK=1.8 at 20 K. The temperature-dependent enhancement cannot be explained by the electron-phonon interaction with a fixed magnitude of the Eliashberg function, which suggests an unexplored mechanism that enhances the coupling parameter at lower temperatures. Our results clearly indicate distinct energy scales in the self-energy, providing insight into the strange metal state as well as the temperature-dependent interplay of many-body interactions.

Published by the American Physical Society
2025
Understanding the corrosion evolution of galvanic steel under simulated marine atmospheric environment using real-time EIS measurement
Authors: Shen Lianfeng , Sun Jinhua , Miao Lei , Gu Haiping , Qiao Shuzhen , Wang Lei , Wei Wei 
Published: February 2025

Purpose
The application of galvanized steel is widespread across industries due to its protective zinc coating that protects against atmospheric corrosion. However, previous studies have primarily focused on long-term corrosion rates rather than the full-scale corrosion behavior of the zinc. This paper aims to study the full-scale corrosion evolution of galvanic steel under simulated marine atmospheric environment using real-time EIS measurement.

Design/methodology/approach
Electrochemical impedance spectroscopy (EIS) provides an advanced method in monitoring such behavior. Therefore, the EIS method has been used to conduct a comprehensive investigation on the corrosion behavior of galvanic steel in a full-time manner.

Findings
The results indicate that the corrosion process of galvanic steel can be divided into three stages: an initial stage with an increased corrosion rate, a subsequent stage with a reduced corrosion rate, and finally a third stage with the lowest and constant corrosion rate. The evolution of corrosion resistance is closely related to changes in composition and structure of the patina layer. In the initial stage, galvanized steel undergoes the formation of soluble ZnCl2 and needle-like Zn5(OH)8Cl2·H2O, which promotes the generation and maintenance of an electrolyte layer, consequently leading to an increase in corrosion rate. With prolonged corrosion time, there is a continuous accumulation of Zn5(OH)8Cl2·H2O within the patina layer, which reduces the content of soluble components and promotes the development of a denser inner layer, thus enhancing corrosion resistance.

Originality/value
This work holds significance in the monitoring of corrosion, understanding the evolution of corrosion and predicting the lifespan of galvanized steel.
Dynamic capabilities of blockchain technology for resilient–sustainable–survival supply chain: empirical evidence from the manufacturing and assembling firms
Authors: Meafa Azz-Eddine , Chaouni Benabdellah Abla , Zekhnini Kamar , Bag Surajit 
Published: February 2025

PurposeUnder a rapidly changing and disruptive environment, the need for resilient, sustainable and survival-oriented performances is currently urgent. To deal with these challenges, the reconfigurable capabilities of blockchain technology (BT) can support supply chains (SC) to be resilient and survive during disruptions while maintaining sustainability goals. Through the lens of the dynamic capability view (DCV), this study aims to investigate the impact of adopting the dynamic capabilities of BT to achieve the resilient–sustainable–survival (RSS) paradigm under a disruptive context.Design/methodology/approachThis study follows the DCV to develop theoretical hypotheses and adopts structural equation modeling to examine and analyze the impact of BT’s capabilities on the triple aspects of the RSS paradigm. It uses the partial least squares technique to evaluate the weight of the correlations among the constructs, test the dependencies of its relationships and assess the model’s power for predicting the outcome variables.FindingsBased on the empirical evidence from the manufacturing and assembling SCs, this study provides insights into the interplay of the sensing, seizing and transforming capabilities of BT, and the most needed ones to fit the expectations of the RSS model. It shows that such capabilities can have a significant impact and can be a powerful tool that contributes to the enhancement of the RSS’s aspects in SC networks.Originality/valueThis study represents one of the initial queries to conceptualize the RSS model of the SC within a disruptive context. For researchers, it adds more understanding of the deployment of the DCV in the technology adoption area. For practitioners, it helps identify the capabilities of BT and their potential to fit the expectations for the RSS paradigm.
The effect of deregulation on bank risk-taking in China: a balance sheet capacity perspective
Authors: Fang Yi , Peng Xinman 
Published: February 2025

PurposeThe impact of banking deregulation on firms and economic growth is heavily researched, but not the effects on banks’ risk-taking. This study aims to investigate the impact of China’s 2009 banking deregulation on bank risk-taking, particularly from a balance sheet capacity perspective.Design/methodology/approachUsing a difference-in-differences approach, this study examines how deregulation affects bank risk-taking. A three-stage regression strategy is employed to conduct mechanism analysis.FindingsThe results reveal that deregulated banks exhibit higher levels of risk-taking. Mechanism analysis confirms the bank balance sheet capacity channel: deregulation helps strengthen the net interest margin of deregulated banks, which enhances their balance sheet capacity and subsequently increases their risk appetite. In addition, deregulation improves firms’ access to long-term credit in regions with limited credit availability, especially for smaller firms, thereby expanding the financial sector’s service outreach.Practical implicationsWhile banking deregulation enhances credit availability for firms and supports the real economy, it also raises banks’ risk-taking, posing challenges to financial stability. Our study highlights the trade-off between supporting the real economy and maintaining financial stability under banking deregulation.Originality/valueThis study fills a gap in research on the effects of banking deregulation on bank risk-taking, highlighting the critical role of balance sheet capacity in this process.
Improvising e-services in Tanzanian public service delivery: model proposal and validation
Authors: Mbano Goodluck Michael , Mwangakala Hilda A. , Shao Deo , Alexopoulos Charalampos , Saxena Stuti 
Published: February 2025

Purpose
This study aims to propose a model for Tanzanian electronic service (e-service) improvisation via public service delivery formats and empirically validate it such that the determinants [namely, information quality (IQ), service quality (SEQ), net impact, top management support (TMS)] of the user satisfaction and the intention to continue using the e-services have been determined.

Design/methodology/approach
A quantitative methodology and a survey research method has been adopted with responses solicited from the Information and Communication Technology officers and accountants working at the Ministry of Finance, Bank of Tanzania, etc. based at Dar es Salam and Dodoma.

Findings
IQ, SEQ, system quality and net impact have a positive and significant impact on user satisfaction and intention to continue to use e-services. However, results for TMS were not found to have any bearing on the user satisfaction and intention to continue to use e-services.

Originality/value
With the extant literature primarily hinged on the understanding of the electronic government services from the efficacy perspective, this study contributes to the literature in two ways, namely, proposing a model for e-service improvisation and empirically validating it in the context of Tanzania.
Bridging the health-care gap: understanding continued telemedicine-usage behaviour in emerging economies
Authors: Singh Aarti , Padhy Ramakrushna , Sahu Aditya Kumar , Chaudhuri Atanu 
Published: February 2025

Purpose
This study aims to analyse the role of factors responsible for continued telemedicine usage in emerging economies.

Design/methodology/approach
A sequential mixed-methods approach was used to analyse the data. This included in-depth interviews with telemedicine users to identify the factors influencing their continued telemedicine usage, followed by quantitative analysis to empirically validate the relationship postulated within the research model.

Findings
The primary findings show that attitude, social influence and satisfaction directly impact users’ continued intention to use telemedicine services. These factors underscore the importance of both individual perceptions and external influences in shaping intention to continue to use telemedicine services.

Practical implications
The results show that factors such as satisfaction, attitude and social influence impact the continued usage of telemedicine services in emerging economies. Specific policy initiatives and awareness programs can be implemented to promote long-term telemedicine usage. In addition, improving apps with user-friendly interfaces, local language options and voice commands, alongside enhanced security measures, would serve to build trust in, and improve accessibility to, telemedicine.

Social implications
The study’s findings can be used to improve health-care services in areas where facilities are inaccessible.

Originality/value
This research explains the intention to continue telemedicine usage through a multi-theoretic perspective that combines technology continuance theory and the unified theory of acceptance and use of technology.
The integration of energy storage system in solar power generation: a bibliometric perspective of renewable energy
Authors: Mohd Aripin Norhana , Hussain Suhaidah , Khai Loon Lee , Mahmud Fatimah , Alimin Nur Sofia Nabila 
Published: February 2025

Purpose
This study aims to review recent advancements in solar energy generation and identify future research trends, with a focus on integrating energy storage systems to enhance the reliability and efficiency of solar power.

Design/methodology/approach
This study involved conducting a review of 313 articles published between 2014 and 2024 in the Scopus database. The research applied bibliometric analysis techniques, which are bibliographic coupling and co-occurrence analysis, to examine recent advancements and future trends in solar energy generation.

Findings
This research highlights recent field contributions through bibliographic coupling, indicating that solar PV is the most environmentally sustainable renewable energy source, with energy storage systems, particularly hydrogen, critical for stability. In addition, co-occurrence analysis on the future research avenue highlights optimizing green hydrogen production and hybrid storage systems while exploring innovative financing models to enhance grid stability and facilitate a sustainable energy transition.

Research limitations/implications
This review recognizes some limitations in bibliometric analysis, such as relying solely on the Scopus database, subjective interpretations of themes and the challenge of distinguishing self-citations from external ones, which can give a misleading impression of a publication’s influence.

Originality/value
This study focuses on exploring how energy storage systems can be integrated with solar energy generation. Although there has been extensive research on renewable energy, this specific intersection has been largely overlooked. By using bibliometric analysis, this study aims to highlight recent developments and future directions in this critical area, ultimately providing valuable insights that can help shape both academic research and practical policy decisions.
The experience of wellbeing practices in project-based organisations
Authors: Kapsali Maria , Prouska Rea , Hajikazemi Sara 
Published: February 2025

PurposeProject-based organisations (PBOs) experience high labour turnover due to wellbeing issues arising from inefficient policies. An in-depth review of previous attributes this to the fact that the experiences and perspectives of project managers are considered neither in organisational policy/practice nor in wellbeing research. This study addresses this gap with two questions: (1) How do project managers experience wellbeing practices in PBOs? (2) What factors enable or restrict the implementation of these practices from their perspective?Design/methodology/approachThis exploratory qualitative study collected interview data from 19 PBO employees in Western Europe across three sectors. Participants assessed the implementation and influencing factors of wellbeing practices in their organisations. Narratives were analysed thematically, followed by sentiment analysis to cross-reference the emotional tone of each theme.FindingsThe findings provided a framework showing the necessary shift in the project managers’ role in PBO wellbeing policy and devolution of voice practices. The results also provided two new conceptual themes specific to wellbeing in PBOs: (1) voice structure and policy and (2) demarcation of the project leader role.Originality/valueThe study introduces a new framework with two new theoretical concepts to improve wellbeing in PBOs. These concepts promote inclusivity of wellbeing concerns via new feedback structures and clarify the project manager’s role in advocating employee voice. The proposed solutions aim to improve knowledge in the research field of wellbeing providing the perspective of the project manager, which currently is lacking from theory.