bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Mometasone Effective in Treating Otitis Media with Effusion?
Authors: Al-Zaidi Haider Majid Haider 
Published: January 2023

Otitis media with effusion (OME) is the long-term deposition of mucus in the middle ear cleft. It is the leading cause of childhood hearing loss and a common childhood infection. It can impair communication and life quality. OME's direct and indirect costs are also crucial. Improving OME care is crucial. This study examines intranasal mometasone's efficacy in treating otitis media with effusion. A clinical trial study was conducted during a period from January 2021 to June 2022. It included 80 patients suffering from otitis media with effusion bilaterally (160 ears) who had an intact tympanic membrane and tympanometry type B. These patients were included only if they had a hearing change or loss noted by the parents or by the patient if he or she could complain for three months or more. These patients were split into two groups. Group A had 80 ears (40 patients) who got one puff of mometasone furoate nasal spray in each nostril every day for three months, and Group B had 80 ears (40 patients) who got one puff of seawater nasal spray in each nostril every day for the same period. On the first visit, otoscopic findings were recorded, and all patients had pure-tone audiometry and tympanometry performed. All of the above-mentioned measures were repeated and compared to the records from the first visit at the end of the three months of treatment. After treatment, 75% of ears in Group A changed from type B to type A tympanometry. This was significantly higher than in Group B, where only 15% of ears changed from type B to type A tympanometry. Regarding retraction, 75% of ears in Group A showed no retraction after treatment with mometasone furoate, while in Group B, it was 40%. The average pure-tone audiometry score in Group A improved after therapy. Corticosteroids are effective in the treatment of otitis media with effusion and safer when used as topical intranasal steroids than systemic preparations.
Virtual Parenting Welcome To Face To Face Learning Acording To Processes In The Covid- 19 Pandemic Time At The Untung Suropati II SDK Sidoarjo
Authors: Widianingtyas Sisilia 
Published: January 2023

Wabah penyakit coronavirus (COVID-19) ditetapkan sebagai Kedaruratan Kesehatan Masyarakat yang meresahkan dunia. Seperti banyak orang sudah ketahui bahwa penyakit Corona virus ini ditularkan melalui kontak langsung dengan percikan dari saluran napas orang yang terinfeksi (yang keluar melalui batuk dan bersin). Diperlukan kewaspadaan untuk mencegah kemungkinan penyebaran COVID-19 dosetiap lini termasuk di lingkungan sekolah. Saat ini Kemendikbud bersama tiga kementerian merencanakan untuk menyelenggarakan pelaksanaan tahun ajaran dan tahun akademik baru 2020/2021 secara tatap muka secara langsung, berdasarkan hal tersebut banyak yang perlu di ketahui dan direncanakan agar pembelajaran tatap muka secara langsung bisa berjalan dengan baik dan tentunya aman. Ada kecemasan dan kekhawatiran dari orang tua, untuk mengirim anaknya kembali kesekolah dengan alasan yang bermacam-macam. Karena tidak dipungkiri perlu persiapan banyaknya hal mulai dari kesiapan pihak sekolah untuk menyiapkan sarana prasana pendukung. Tujuan pengabdian masyarakat saat ini adalah untuk memberikan pendidikan kesehatan ini bagi, guru dan staf, orang tua, pengasuh, anggota masyarakat, serta anak-anak dalam menciptakan sekolah yang aman dan sehat. Agar nantinya dikala pembelajaran luring sudah dimulai bisa melakukan pencegahan, deteksi dini dan pengendalian COVID-19 di sekolah dan fasilitas pendidikan lainnya. Ada peningkatan pengetahuan khususnya dalam upaya menjaga kesehatan di masa pandemi dan pentingnya membiasakan perilaku hidup sehat di rumah, dan di sekolah
Empowerment Of Family The “Ngabdi Wong Tuwo” With Caregiver Training For Elderly Stroke Suffering In Jabung Village Plupuh Sragen
Authors: Ningsih Warti 
Published: January 2023

Latar belakang : hidup dengan menderita stroke pada lansia memberikan pengaruh terhadap kehidupan keluarga. Kondisi stroke pada lansia menambah beban ketergantungan lansia terhadap keluarga. Sebagai support sistem dalam merawat lansia dengan stroke dibutuhkan pengetahuan, ketrampilan yang memadai. Keluraga yang memiliki lansia dengan stroke 10 diantaranya tidak mengetahui cara merawat pasien stroke dari 23 lansia dengan stroke di Desa Jabung Plupuh Sragen. Metode : studi ini dilakukan dengan metode deskriptif. Dilakukan intervensi berupa pelatihan caregiver yang sebelumya kita lakukan identifikasi pengetahuan sebelum dan sesudah pelatihan, dimana pelatihan diikuti oleh 20 kader lansia dan 20 care giver lansia dengan stroke. Pendampingan keluarga dilakukan pada 13 keluarga yang merawat lansia dengan stroke selanjutnya kita evaluasi terkait dukungan keluarga sebelum dan sesudah pendampingan. Hasil : pengetahuan kader lansia sebelum pelatihan 50 % cukup setelah dilakukan pelatihan sebagian besar baik 75 %. Pengetahuan care giver sebelum pelatihan sebagian besar kurang 70 % menjadi sebagian besar baik 65 % setelah dilakukan penelitian. Dukungan keluarga setelah dilakukan pada 13 keluarga sebelumnya pendampinag 53,8 % dukungan keluarga baik meningkat menjadi hampir seluruhnya 92,3% baik. Kesimpulan : pelatihan dan pendampingan keluarga dalam merawat lansia yang stroke dapat meningkatkan pengetahuan dan dukungan keluarga sebagai care giver lansia yang mengalami stroke
The association between diabetes status and latent-TB IGRA levels from a cross-sectional study in eastern China
Authors: Chen Cheng , Hu Xinsong , Shao Yan , Song Honghuan , Li Guoli , Lu Wei , Martinez Leonardo , Xu Jianfang , Zhu Limei 
Published: January 2023

BackgroundThere is a debate regarding the sensitivity of the QuantiFERON-TB Gold In-Tube (QFT) among people with diabetes, and prior studies have shown heterogeneous results. We evaluated whether the QFT TB antigen was modified among persons with differing diabetes status and other related risk factors.MethodsA cross-sectional study of 5,302 people was conducted to screen latent tuberculosis infection (LTBI) in eastern China. The QFT assay was performed as an indicator of LTBI. Fasting plasma glucose (FPG) was collected from each participant; the definition of diabetes followed the guidelines from the American Diabetes Association. Participants were classified into normoglycemia, prediabetes, undiagnosed diabetes, and previously diagnosed diabetes to evaluate the relationship between the QFT TB antigen and distinct diabetes status.ResultsTB antigen values from the QFT were statistically different among participants with differing diabetes status (P = 0.008). Persons with undiagnosed diabetes had a higher TB antigen value (0.96 ± 0.20) than persons with normoglycemia (0.50 ± 0.02, P &lt; 0.05). However, the TB antigen values demonstrated no significant difference among the four different diabetic groups when stratified by the standard cutoff for the QFT (P = 0.492 for the positive group and P = 0.368 for the negative group). In a linear regression model, we found that FPG, age, and smoking were positively associated with the QFT TB antigen value (P = 0.017, P &lt; 0.001, and P &lt; 0.001).ConclusionsDiabetes status had little influence on the level of QFT TB antigen response among IGRA-positive persons. However, FPG, old age, and smoking were important risk factors for increasing levels of QFT TB antigen.
Relationship between hydrogeochemical characteristics of hot springs and seismic activity in the Jinshajiang fault zone, Southeast Tibetan Plateau
Authors: Liu Jie , Zhou Xiaocheng , Li Ying , He Miao , Li Jingchao , Dong Jinyuan , Tian Jiao , Yan Yucong , Ouyang Shupei , Liu Fengli 
Published: January 2023

Significant anomalous hydrogeochemical changes in hot spring water are detected during strong seismic cycles. It is now necessary to clarify the relationship between tectonic movements, earthquakes and the evolution of hot springs. In this paper, laboratory analyses of major, trace elements, δD, δ18O and 87Sr/86Sr values of 28 hot spring waters in the Jinshajiang fault zone (JSJFZ) in the northwestern boundary of the Sichuan-Yunnan block were conducted. The results showed that the primary source of water for JSJFZ hot springs was atmospheric precipitation. The geothermal reservoir temperature variation based on the silicon enthalpy mixing model ranged from 73 to 272°C. And the circulation depth range was 1.2–5.4 km. The segmentation characteristics of the 87Sr/86Sr values were related to the influence of source rocks on groundwater cycle processes. A conceptual model of the hydrologic cycle of hot springs explained the spatial distribution of earthquakes associated with tectonic movements. The Batang segment had the strongest water-rock reaction, the highest reservoir temperature and the deepest circulation depth; meanwhile, it was also an earthquake prone area. The fluid circulation of the JSJFZ corresponds well with the seismicity, which indicates that the hydrological characteristics of the hot spring water in a fracture zone play a crucial role in receiving information on seismic activity.
A method to evaluation rock brittleness based on statistical damage constitutive parameters
Authors: Gao Meiben , Li Tianbin , Gao Yang , Zhang Yan , Yang Qingwen , He Zhihao , He Qingqing 
Published: January 2023

Brittleness is an important parameter to evaluate the performance of rock engineering. A scientific and reasonable brittleness evaluation method is of great significance to theoretical research and the engineering practice of rock mechanics. In view of the existing statistical constitutive models of rock based on the Weibull distribution being able to express various constitutive behaviors well, such as brittleness, plasticity, strain softening, this paper wants to determine rock brittleness from constitutive models. First, the parameter m, which can effectively reflect the overall characteristics of the rock stress-strain curve, and the parameter δ, which can reflect the post-peak characteristics, are selected. Then, a brittle evaluation method based on rock statistical damage constitutive parameters is proposed, and the brittleness index Bm (Bm = m·δ) is established. The feasibility is verified by the testing data of granite, sandstone and marble under different conditions. The results show that the brittleness of those hard rocks decrease with the increasing of confining pressure. For confining pressures of 5 MPa and 15 MPa, the brittleness of granite under triaxial unloading test is greater than that under triaxial compression test. The calculation results quantitatively reflect the brittle characteristics of sandstone, marble and granite in the test. Compared with the existing representative brittleness indexes, it is found that the brittleness index Bm can effectively reflect the characteristics of rock brittleness decreasing with increasing confining pressure and enhancement under unloading stress path. This paper provides a way to evaluate rock brittleness from the perspective of a constitutive model, which is helpful to enrich our understanding of rock brittleness.
Experimental study and weighting analysis of factors influencing gas desorption
Authors: He Xin , Cui Hong-qing , Zhang Hang , Wang Zhen-zhi , Wang Ze-hua , Shi Guang-shan 
Published: January 2023

Gas is one of the necessary contributing factors for coal and gas outburst accidents, and the gas desorbed in coal is the energy carrier in the outburst process. The study of gas desorption laws is the premise and basis for gas content determination and gas accident prevention. To solve the problem of inaccurate gas content measurement due to the unclear characteristics of rapid gas desorption in 0–10 s, the gas desorption experimental device was improved, the influence factors of gas desorption were studied experimentally, and a comprehensive analysis method was proposed based on the gas desorption rate, gas desorption efficiency, initial gas desorption amount and total desorbed gas. The experiment analysed five factors that affected gas desorption, including the degree of metamorphism, type of failure, particle size, pressure and temperature. The results show that there is a monotonically decreasing power function relationship between the initial gas desorption rate and time and a monotonically increasing logarithmic function relationship between the gas desorption amount and time; the curve has a limit value. The gas desorption amount is large in 0–10 s and increases slowly afterwards. Among the factors affecting gas desorption, their importance decreases in the order of pressure &gt; metamorphism &gt; particle size &gt; failure type &gt; temperature. This study is of great practical value for the calculation of gas losses in gas content determination, and the resulting gas desorption laws are of great importance in guiding gas control work.
Tunneling construction technology of shafts and cross-passages under strictly controlling deformation of the existing railway
Authors: Liu Liu , Xu Gongwen , Li Rongxian , Fang Zhichun , Chen Hongwen , Wu Siqi , Xu Wenbo , Han Bing , Ma Chaoyi , Shen Qian 
Published: January 2023

Underground construction will have more or less adverse effects on adjacent existing buildings with more and more existing buildings above ground. However, this situation has only been reported by a small number of researchers. In view of this, this article takes the existing airport line shaft and horizontal passage project in the western suburb of Beijing Metro Line 12 as the background to study the impact of the construction of subway station and shaft passage on the adjacent existing railway. Based on the above project reality, under the action of pavement load, the effects of different parameters (the distance between the surface measuring point and the middle line of the transverse passage and the substep of construction loading sup step) on the surface settlement and track deformation of the shaft and cross-passage through the existing railway are studied by numerical analysis method. The calculation results show that the construction method of shaft and cross passage is reasonable. The comprehensive reinforcement measures of subgrade, rail and hole are effective, effectively controlling the deformation of subgrade and rail within the standard value (surface settlement ≤60 mm, rail deformation ≤6 mm). In addition, the numerical simulation data can better represent the actual situation as a whole.
Post-collisional magmatism associated with the final closure of the Rushan-Pshart Meso-Tethys Ocean in Pamir, Tajikistan: Inference from Cretaceous igneous rocks of the Pshart accretionary complex
Authors: Yogibekov Dzhovid , Sang Miao , Xiao Wenjiao , Mamadjonov Yunus , Zhou Chuanming , Yang He , Mao Qigui , Aminov Jovid , Khalimov Gufron , Ashuraliev Sohibnazar 
Published: January 2023

The Pamir orogen was formed by the subducted accretion and amalgamation of Cimmerian terranes from the northern margin of Gondwana with the southern margin of Eurasia. The Mesozoic magmatic rocks are widespread in Pamir and record the tectonic evolution in different stages. The Rushan–Pshart suture zone represents an ancient ocean between Central and Southern Pamir. This paper reports the petrography, geochronology, and geochemistry of Cretaceous granites and diabase dikes that intrude into the Pshart complex. The granites were emplaced between 124 and 118 Ma, based on their zircon U-Pb ages. These granites are characterized by high-K calc-alkaline, low magnesian, and high SiO2, A/CNK, and K2O+Na2O values. They also display strong depletion of Ba, Sr, Eu, and Ti and comparatively weak negative Nb anomalies in spidergrams. Thus, we proposed in this study that these are highly fractionated, strongly peraluminous S-type granites. They were generated by the partial melting of the metasedimentary rocks in the plagioclase stability field and underwent subsequent fractional crystallization during their ascent. The diabase dikes contain low SiO2, and high MgO levels and negative Nb and Ta anomalies, which were interpreted to form in an extensional environment. Late Jurassic–Early Cretaceous closure of the Rushan–Pshart Ocean and subsequent foundering of its oceanic lithosphere caused local extension and upwelling of the asthenospheric mantle. The underplating of mafic magma provided a heat source to melt the metasedimentary-derived granitic that formed in the initial post-collisional environment. The subsequent local extension caused the emplacement of diabase dikes. Based on our new data and combined with data from previous studies, we concluded that the Rushan–Pshart suture zone is the remnant of the Meso-Tethys Ocean and may represent the western continuation of the Bangong–Nujiang suture of the Tibetan Plateau.
Association of objective and subjective parameters of obstructive sleep apnea with plasma aldosterone concentration in 2,066 hypertensive and 25,368 general population
Authors: Wang Hui , Heizhati Mulalibieke , Li Nanfang , Gan Lin , Lin Mengyue , Yang Wenbo , Li Mei , Yao Ling , Liu Miaomiao , Maitituersun Adalaiti , Liu Shasha , Wu Zihao , Xiamili Zuhere , Tong Ling , Lin Yue , Luo Qin , Hong Jing 
Published: January 2023

Study objectivesObstructive sleep apnea (OSA) severity has been suggested in aldosterone elevation in resistant hypertension, whereas it is undetermined in the rest population. We explored the association of OSA parameters with plasma aldosterone concentration (PAC) in participants with and without hypertension.MethodsWe enrolled clinically hypertensive patients with polysomnography and PAC data under no interfering agents, compared (log) PAC, and assessed the linearity of log PAC by tertiles (T1/2/3) of sleep parameters and their association using linear regression by gender and age. We enrolled participants with and without hypertension who had No-SAS scale and PAC data from the community and duplicated the observations from clinical setting considering age, gender, and presence of hypertension.ResultsOf the 2,066 clinical patients with hypertension (1,546 with OSA), men participants (n=1,412), log apnea–hypopnea index (p=0.043), apnea index (AI, p=0.010), and lowest oxygen saturation (LSaO2, p=0.013) showed significant linearity with log PAC. Log AI (B=0.04, 95%CI: 0.01,0.07, p=0.022) and log LSaO2 (B=−0.39, 95%CI: −0.78,−0.01, p=0.044) showed significant positive and negative linear associations with log PAC in regression. In community dwellers, 6,417 participants with untreated hypertension (2,642 with OSA) and 18,951 normotensive participants (3,000 with OSA) were included. Of the men participants with and without hypertension, the OSA group showed significantly higher (log) PAC than did their counterparts, and log No-SAS score showed positive association with log PAC (hypertension: B=0.072, 95%CI: 0.002,0.142, p=0.043; normotension: B=0.103, 95%CI: 0.067,0.139, p&lt;0.001) in linear regression analysis, which were consistent in all age groups.ConclusionsOSA parameters were positively associated with PAC in normotensive and hypertensive participants, indicating that OSA may increase circulating aldosterone, especially in men.
The association between the reduction of body weight and new-onset type 2 diabetes remission in middle-aged Japanese men: Population-based Panasonic cohort study 8
Authors: Matsui Takaaki , Okada Hiroshi , Hamaguchi Masahide , Kurogi Kazushiro , Murata Hiroaki , Ito Masato , Fukui Michiaki 
Published: January 2023

AimThis study aimed to investigate the association between change in body weight (BW) and type 2 diabetes remission in Japanese men with new-onset type 2 diabetes.MethodsThis study enrolled 1,903 patients with new-onset type 2 diabetes between 2008 and 2013 from a medical health checkup program conducted by the Panasonic Corporation, Osaka, Japan. The baseline was defined as the year of new-onset diabetes. We assessed the type 2 diabetes remission five years after baseline and the association between the change in BW and type 2 diabetes remission using logistic regression analyses. To evaluate the predictive performance of the change in BW, we employed the receiver operating characteristic curves and the area under the receiver operating characteristic (ROC) curve (AUC).ResultsThe BW loss was associated with type 2 diabetes remission in the participants with a BMI ≥25 kg/m2 but not in the participants with a BMI &lt;25 kg/m2. The odds ratios were 1.96 (95% CI: 1.19–3.29) and 3.72 (95% CI: 2.14–6.59) in the participants with a loss of 5–9.9% and loss of ≥10% for five years, respectively, in the participants with a BMI ≥25 kg/m2 (reference; stable group [0.9% gain to 0.9% loss]). The AUC and cut-off values for the rate of change in BW for type 2 diabetes remission were 0.59 and 5.0%.DiscussionBody weight loss of ≥5% effectively achieved diabetes remission in Japanese men with a BMI ≥25 kg/m2 and new-onset type 2 diabetes.
Association of exposure to air pollutants with gestational diabetes mellitus in Chiayi City, Taiwan
Authors: Yan Yuan-Horng , Chien Chu-Chun , Wang Panchalli , Lu Mei-Chun , Wei Yu-Ching , Wang Jyh-Seng , Wang Jun-Sing 
Published: January 2023

IntroductionWe investigated the associations of exposure to particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5) and several gaseous pollutants with risk of gestational diabetes mellitus (GDM) in Taiwan.MethodsWe retrospectively identified pregnant women who underwent a two-step approach to screen for GDM between 2006 and 2014. Information on concentrations of air pollutants (including PM2.5, sulfur dioxide [SO2], nitrogen oxides [NOx], and ozone [O3]) were collected from a single fixed-site monitoring station. We conducted logistic regression analyses to determine the associations between exposure to air pollutants and risk of GDM.ResultsA total of 11210 women were analyzed, and 705 were diagnosed with GDM. Exposure to PM2.5 during the second trimester was associated with a nearly 50% higher risk of GDM (odds ratio [OR] 1.47, 95% CI 0.96 to 2.24, p=0.077). The associations were consistent in the two-pollutant model (PM2.5 + SO2 [OR 1.73, p=0.038], PM2.5 + NOx [OR 1.52, p=0.064], PM2.5 + O3 [OR 1.96, p=0.015]), and were more prominent in women with age &lt;30 years and body mass index &lt;25 kg/m2 (interaction p values &lt;0.01).DiscussionExposure to PM2.5 was associated with risk of GDM, especially in women who were younger or had a normal body mass index.