bluuebunny/crossref_metadata_2025_split huggingface dataset:
High optoelectronic quality of AZO films grown by RF-magnetron sputtering for organic electronics applications
Authors: Silva Hálice de Oliveira Xavier , Faraco Thales Alves , Maciel Indhira Oliveira , Quirino Welber Gianini , Fragneaud Benjamin , Pereira Paula Gomes , Legnani Cristiano 
Published: April 2023

Abstract
Aluminum-doped zinc oxide thin films, known by the acronym AZO, were grown by radio-frequency magnetron sputtering method (rf-magnetron sputtering) onto glass substrate at room temperature and without posterior heat treatment. The impact on the structural, electrical, and optical properties of the AZO films was studied as a function of the following deposition parameters: working pressure, rf-power and thickness. Our films showed low electrical resistivity and high transmittance in the visible region comparable to commercial indium tin oxide (ITO) films. We obtained an optimized AZO film with an electrical resistivity of 4.90 × 10−4 Ωcm and presented optical transmittance strikingly high for such a good conductor, with about 98% at 580 nm and an average optical transmittance of about 92% in the visible region. We also built and characterized an organic light-emitting diode (OLED) using the optimized AZO film as a transparent electrode. The AZO-based OLED showed characteristics comparable to a reference ITO-based device, indicating that AZO films have optoelectronic properties good enough to be used in organic electronics. In addition, the results suggest that they are suitable to be employed as transparent conductors in flexible polymeric substrates since their synthesis was performed without intentional heating.
Systematic study of tunable laser cooling for trapped-ion experiments
Authors: Kulosa A P , Prudnikov O N , Vadlejch D , Fürst H A , Kirpichnikova A A , Taichenachev A V , Yudin V I , Mehlstäubler T E 
Published: April 2023

Abstract
We report on a comparative analysis of quenched sideband cooling in trapped ions. We introduce a theoretical approach for time-efficient simulation of the temporal cooling characteristics and derive the optimal conditions providing fast laser cooling into the ion’s motional ground state. The simulations were experimentally benchmarked with a single 172Yb+ ion confined in a linear Paul trap. Sideband cooling was carried out on a narrow quadrupole transition, enhanced with an additional clear-out laser for controlling the effective linewidth of the cooling transition. Quench cooling was thus for the first time studied in the resolved sideband, intermediate and semi-classical regime. We discuss the non-thermal distribution of Fock states during laser cooling and reveal its impact on time dilation shifts in optical atomic clocks.
Dynamical friction due to fuzzy dark matter on satellites described by axisymmetric logarithmic potentials
Authors: Vitsos Andreas , Gourgouliatos Konstantinos N. 
Published: April 2023

Abstract
A plausible dark matter candidate is an ultralight bosonic particle referred to as fuzzy dark matter. The equivalent mass-energy of the fuzzy dark matter boson is ∼ 10-22 eV and has a corresponding de Broglie wavelength of kiloparsec scale, thus exhibiting wave behaviour in scales comparable to a galactic core, which could not appear in conventional cold dark matter models. The presence of fuzzy dark matter in galactic clusters will impact the motion of their members through dynamical friction. In this work, we present simulations of the dynamical friction on satellites traversing an initially uniform fuzzy dark matter halo. We focus on the satellites whose shapes are beyond spherical symmetry described by ellipsoidal and logarithmic potentials. We find that the wakes created on the fuzzy dark matter halo due to the passage of such satellites are qualitatively different from those generated by spherically symmetric ones. Furthermore, we quantify the dynamical friction coefficient for such systems, finding that the same satellite may experience a drag differing by a factor of 5 depending on its ellipticity and the direction of motion. Finally, we find that the dynamical friction time-scale is close to Hubble time, assuming a satellite of 1011
M
⊙ traversing at 103 km/s a FDM halo whose mean density is ∼ 106
M
⊙ kpc-3.
Large Telescope Wind Load Estimation with Gradient Segments Superposition and its Servo Control
Authors: Yu Jia-Heng , Xue Song , Luan Tian , Wang Long-Yang , Lian Pei-Yuan , Yan Yue-Fei , Kong De-Qing , Zhao Wu-Lin , Xu Qian , Wang Cong-Si 
Published: April 2023

Abstract
Obtaining the wind load distribution on the telescope aperture is very important to estimate its influence and reduce the wind disturbance on the telescope system. The aperture of the radio telescope structure can be as large as 100 m and therefore, the uniform wind load on the aperture assumption is not suitable for the radio telescope with large aperture. In this paper, a gradient segments superposition method for calculating the wind load has been proposed. The proposed method has been constructed by combining two regional divisions. First, reflecting surface has been evenly divided in the altitudinal direction. Second, the reflecting surface has been divided into several uniform rings assuming that the wind load coefficient on different rings are different. For the 110 m aperture radio telescope, the wind load estimation results differ by 28%. After that, a structural dynamics model of telescope has been established and a fuzzy PID controller has been designed to reduce wind disturbance. The Root Mean Square Error of telescope pointing under wind disturbance has been reduced by 67.8%. It is suggested that the proposed wind load estimation method has lay a solid foundation for the design of the large telescope system under wind disturbance.
A novel method to pack cryopreserved amniotic membrane for wound dressing—the pathway through validation of a new biological product
Authors: Ogliari Karolyn Sassi , Grudzinski Patrícia Bencke , da Silva Camila Gomes , Immig Mônica Luiza , Halon Maria Laura , Loth Fabrízio Blank , Ogliari Alicia Sassi , Tovo Monique Blauth , Beckenkamp Liziane Raquel 
Published: April 2023

Abstract
Amniotic membrane (AM) has been widely used as a biological dressing for many pathologies and illnesses worldwide, and products derived from this tissue have been commercially available in several countries. In Brazil, regulatory agencies have recently authorized its clinical use as a non-experimental therapy for burns, diabetic and venous stasis ulcers, and intrauterine adhesions. In this study, we present our pathway through validating the first available service in the country of AM cryopreservation, with a protocol for long-term storage in high-efficiency nitrogen cryogenic freezers and a specific way of packing the tissue for optimal clinical handling and efficient storage space utilization while preserving live cells and the tissue’s biological properties. Using gauze as support, cryoprotectant dimethyl sulfoxide and product presentation as a multilayer roll exhibited the best cell viability results and maintained the tissue integrity and presence of stem/progenitor cells. Essential proteins involved in tissue regeneration and immune and antimicrobial control were detected from the secretome of cryopreserved tissue similar to fresh tissue. Furthermore, immunogenic markers, such as human leukocyte antigens, were detected at very low levels in the tissue, confirming their low immunogenicity. Finally, we demonstrate that the tissue can be kept under refrigerated conditions for up to 7 d for further use, maintaining sterility and considerable cell viability. Our cryopreservation and storage protocol kept the AM viable for at least 20 months. In conclusion, this study enabled us to determine a novel efficient protocol for long-term AM preservation for future clinical applications.
Vitexin loaded mixed polymeric micelles: preparation, optimization, evaluation and anti-osteoporotic effect
Authors: Zhang Jian , Li Xiaoxiao , Xia Xiaoli , Adu-Frimpong Michael , Shen Xinyi , He Qing , Rong Wanjing , Shi Feng , Cao Xia , Ji Hao , Toreniyazov Elmurat , Wang Qilong , Yu Jiangnan , Xu Ximing 
Published: April 2023

Abstract
In this regard, we developed vitexin (Vi)-loaded D-ɑ-tocopherol polyethylene glycol succinate, polyvinylpyrrolidone K30 and sodium cholate mixed micelles (Vi-MMs) mainly for improving oral bioavailability and enhancing anti-osteoporotic effect of Vi. Thin layer dispersion method was employed to prepare Vi-MMs, and then the optimal prescription was optimized by the orthogonal design-response surface method, wherein encapsulation efficiency (EE) was used as optimizing index. The physical properties of Vi-MMs such as appearance morphology, particle size, and zeta potential were also characterized. We further analyzed the in-vitro release of Vi and Vi-MMs in three media and investigated the pharmacokinetics of Vi and Vi-MMs in rats. Anti-osteoporotic activity of Vi and Vi-MMs was assessed by establishing a zebrafish osteoporosis model with prednisone. Drug loading, EE, particle size and zeta potential of the optimized Vi-MMs were 8.58 ± 0.13%, 93.86 ± 1.79%, 20.41 ± 0.64 nm and −10 ± 0.56 mV, respectively. The optimized Vi-MMs were shaped spherically as exhibited by transmission electron microscopic technique, with evident core shell nano-structure, well dispersed. In all three media, the release rate of Vi-MMs was significantly higher than that of free Vi. The oral bioavailability of Vi-MMs was increased by 5.6-fold compared to free Vi. In addition, alleviation of prednisone induced osteoporosis in zebrafish by Vi-MMs further demonstrated good anti-osteoporotic effect. In summary, Vi-MMs exhibited enhanced bioavailability and anti-osteoporotic effect, which is expected to be potential nanocarrier for Vi applications in drug development.
Deposition of inverse opal-like TiO2 thin film with enhanced photoelectrochemical activity by a spin-coating combined with a dip-coating method
Authors: Rustembekkyzy Kuralay , Molkenova Anara , Kaikanov Marat , Atabaev Timur Sh 
Published: April 2023

Abstract
TiO2 thin films with an inverse opal-like structure have attracted considerable attention recently owing to their high potential for a range of applications. In this study, we demonstrated the possibility to deposit TiO2 thin films with an inverse opal-like structure from TiO2 nanoparticle-based slurry paste using a conventional spin-coating process. In addition, we also showed that the photoelectrochemical (PEC) performance of as-fabricated inverse opal-like TiO2 films can be further improved by the dip-coating process. In particular, dip-coated and untreated inverse opal-like TiO2 films exhibit photocurrent densities of ∼66.5 μA cm−2 and ∼40.9 μA cm−2 at 1.23 V versus RHE, respectively. A detailed physicochemical analysis revealed that photocurrent density enhancement (∼38.5%) in dip-coated inverse opal-like films can be attributed to a variety of factors including improved interconnection between TiO2 nanoparticles, higher crystallinity, decreased light reflection, and reduced charge carriers recombination. We strongly believe that these findings will be useful in the development of highly efficient third-generation solar cells, photocatalytic systems, electrochromic devices, and gas sensors.
My Parent, Myself, or My Child: Whose Education Matters Most for Trajectories of Cognitive Aging in Middle Age?
Authors: Gutierrez Sirena , Meza Erika , Glymour M Maria , Torres Jacqueline M 
Published: April 2023

Abstract
The growing body of evidence linking intergenerational education and late-life cognitive decline is almost exclusively from high-income countries, despite rapid intergenerational changes in education in low- and middle-income countries (LMICs). We used data from the Mexican Health and Aging Study (n = 8,822), a cohort study of Mexican adults aged ≥50 years (2001–2018), to evaluate whether parental education (none vs. any formal schooling), one’s own education (less than primary school vs. completion of primary school), or an adult child’s education (less than high school vs. completion of high school) was associated with verbal memory z scores. We used linear mixed models with inverse probability of attrition weights. Educational attainment in all 3 generations was associated with baseline verbal memory scores, independent of the prior generation’s education. Lower parental (β = −0.005, 95% confidence interval: −0.009, −0.002) and respondent (β = −0.013, 95% confidence interval: −0.017, −0.010) educational level were associated with faster decline in delayed (but not immediate) verbal memory z scores. Associations between adult child’s education and respondent’s verbal memory decline varied by exposure specification. The educational attainment of parents and adult children may influence the cognitive aging of middle-aged and older adults in LMICs. These results have important implications given recent structural shifts in educational attainment in many LMICs.
Nutritional Blood Concentration Biomarkers in the Hispanic Community Health Study/Study of Latinos: Measurement Characteristics and Power
Authors: Boe Lillian A , Mossavar-Rahmani Yasmin , Sotres-Alvarez Daniela , Daviglus Martha L , Durazo-Arvizu Ramon A , Thyagarajan Bharat , Kaplan Robert C , Shaw Pamela A 
Published: April 2023

Abstract
Measurement error is a major issue in self-reported diet that can distort diet-disease relationships. Use of blood concentration biomarkers has the potential to mitigate the subjective bias inherent in self-reporting. As part of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) baseline visit (2008–2011), self-reported information on diet was collected from all participants (n = 16,415). The HCHS/SOL also included annual telephone follow-up, as well as a second (2014–2017) and third (2020–2023) clinic visit. Blood concentration biomarkers for carotenoids, tocopherols, retinol, vitamin B12, and folate were measured in a subset of participants (n = 476) as part of the Study of Latinos: Nutrition and Physical Activity Assessment Study (SOLNAS) (2010–2012). We examined the relationships among biomarker levels, self-reported intake, Hispanic/Latino background (Central American, Cuban, Dominican, Mexican, Puerto Rican, or South American), and other participant characteristics in this diverse cohort. We built regression calibration–based prediction equations for 10 nutritional biomarkers and used a simulation to study the power of detecting a diet-disease association in a multivariable Cox model using a predicted concentration level. Good statistical power was observed for some nutrients with high prediction model R2 values, but further research is needed to understand how best to realize the potential of these dietary biomarkers. This study provides a comprehensive examination of several nutritional biomarkers within the HCHS/SOL, characterizing their associations with subject characteristics and the influence of the measurement characteristics on the power to detect associations with health outcomes.
Conditional indirect genetic effects of caregivers on brood in the clonal raider ant
Authors: Piekarski Patrick K , Valdés-Rodríguez Stephany , Kronauer Daniel J C 
Published: April 2023

Abstract
Caregivers shape the rearing environment of their young. Consequently, offspring traits are influenced by the genes of their caregivers via indirect genetic effects (IGEs). However, the extent to which IGEs are modulated by environmental factors, other than the genotype of social partners (i.e., intergenomic epistasis), remains an open question. Here we investigate how brood are influenced by the genotype of their caregivers in the clonal raider ant, Ooceraea biroi, a species in which the genotype, age and number of both caregivers and brood can be experimentally controlled. First, we used four clonal lines to establish colonies that differed only in the genotype of caregivers and measured effects on foraging activity, as well as IGEs on brood phenotypes. In a second experiment, we tested whether these IGEs are conditional on the age and number of caregivers. We found that caregiver genotype affected the feeding and foraging activity of colonies, and influenced the rate of development, survival, body size, and caste fate of brood. Caregiver genotype interacted with other factors to influence the rate of development and survival of brood, demonstrating that IGEs can be conditional. Thus, we provide an empirical example of phenotypes being influenced by IGE-by-environment interactions beyond intergenomic epistasis, highlighting that IGEs of caregivers/parents are alterable by factors other than their brood’s/offspring’s genotype.
Attention-based GCN integrates multi-omics data for breast cancer subtype classification and patient-specific gene marker identification
Authors: Guo Hui , Lv Xiang , Li Yizhou , Li Menglong 
Published: April 2023

AbstractBreast cancer is a heterogeneous disease and can be divided into several subtypes with unique prognostic and molecular characteristics. The classification of breast cancer subtypes plays an important role in the precision treatment and prognosis of breast cancer. Benefitting from the relation-aware ability of a graph convolution network (GCN), we present a multi-omics integrative method, the attention-based GCN (AGCN), for breast cancer molecular subtype classification using messenger RNA expression, copy number variation and deoxyribonucleic acid methylation multi-omics data. In the extensive comparative studies, our AGCN models outperform state-of-the-art methods under different experimental conditions and both attention mechanisms and the graph convolution subnetwork play an important role in accurate cancer subtype classification. The layer-wise relevance propagation (LRP) algorithm is used for the interpretation of model decision, which can identify patient-specific important biomarkers that are reported to be related to the occurrence and development of breast cancer. Our results highlighted the effectiveness of the GCN and attention mechanisms in multi-omics integrative analysis and the implement of the LRP algorithm can provide biologically reasonable insights into model decision.
Neural reinstatement of context memory in adults with autism spectrum disorder
Authors: Justus Sidni A , Mirjalili Soroush , Powell Patrick S , Duarte Audrey 
Published: April 2023

Abstract
Autism spectrum disorder (ASD) is associated with episodic memory impairment. However, episodic memories include a variety of contextual details, and it is difficult to solely rely on behavioral data to assess how specifically (i.e. event-specific reinstatement) an event is remembered. We applied encoding-retrieval representational similarity (ERS) analysis to EEG data to assess event-specific ERS for object-context associations in a sample of 34 adults (17 with, 17 without ASD). Participants studied objects presented alongside 2 contextual features: scene/color, and attention was directed toward one object-context relationship. At retrieval, memory was assessed for the object and both contexts. Behavioral results revealed no group differences in item or context memory performance. ERS results revealed group temporal differences in reinstatement. Results may indicate differences in both encoding (i.e. fewer perceptual details) and retrieval (i.e. ineffectively skipping through memory fragments) in ASD and should be further investigated in studies modulating the perceptual detail required for memory decisions. Results highlight the utility of ERS as a methodology used to evaluate episodic reinstatement even in the absence of behavioral differences in memory performance.
MBS: a genome browser annotation track for high-confident microRNA binding sites in whole human transcriptome
Authors: Arancio Walter , Sciaraffa Nicolina , Coronnello Claudia 
Published: April 2023

Abstract
MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) that play a role in many regulatory pathways in eukaryotes. They usually exert their functions by binding mature messenger RNAs. The prediction of the binding targets of the endogenous miRNAs is crucial to unravel the processes they are involved in. In this work, we performed an extensive miRNA binding sites (MBS) prediction over all the annotated transcript sequences and made them available through an UCSC track. MBS annotation track allows to study and visualize the human miRNA binding sites transcriptome-wide in a genome browser, together with any other available information the user is interested in. In the creation of the database that underlies the MBS track, three consolidated algorithms of miRNA binding prediction have been used: PITA, miRanda and TargetScan, and information about the binding sites predicted by all of them has been collected. MBS track displays high-confident miRNA binding sites for the whole length of each human transcript, both coding and non-coding ones. Each annotation can redirect to a web page with the details of the miRNA binding and the involved transcripts. MBS can be easily applied to retrieve specific information such as the effects of alternative splicing on miRNA binding or when a specific miRNA binds an exon–exon junction in the mature RNA. Overall, MBS will be of great help for studying and visualizing, in a user-friendly mode, the predicted miRNA binding sites on all the transcripts arising from a gene or a region of interest.
Database URL https://datasharingada.fondazionerimed.com:8080/MBS
Popular politics, heritage and memories of Chartism in England and Wales, 1918–2020
Authors: Roberts Matthew 
Published: April 2023

Abstract
Chartism has enjoyed a remarkably enduring posthumous life. This article focuses on the politics of remembering the movement via three case studies: the interwar political left, the attempts by the political and cultural establishment to co-opt Chartism since the 1980s, and the role of Chartism in the contemporary and ongoing campaigns for democratic renewal promoted by a range of heritage organizations and groups. By drawing on critical heritage studies, as well as a range of material – from press reports to ephemera and the built environment – this article shows how forms of remembrance and the practices of commemoration surrounding Chartism were (and are) far from static and repetitive but evolving, dynamic and contested.