bluuebunny/crossref_metadata_2025_split huggingface dataset:
PEMERKASAAN PELAKSANAAN SULH DALAM KES-KES HARTANAH MELALUI PEMAKAIAN ARAHAN AMALAN DI MAHKAMAH SYARIAH DI MALAYSIA (Enhancement on the Application of Sulh in Real Property Cases through Practice Directions in Malaysian Shariah Courts)
Authors: Wan  Adnan Wan Azimin , Buang Ahmad Hidayat , Sulaiman Zubaidi 
Published: January 2023

Pemakaian Arahan Amalan membantu pelaksanaan sulh di Mahkamah Syariah pada penyediaan proses kerja bermula daripada pendaftaran kes hingga perintah penghakiman persetujuan dikeluarkan. Kajian ini meneliti kedudukan dan pemakaian Arahan Amalan dalam pelaksanaan sulh dalam kes-kes hartanah di Mahkamah Syariah. Data kajian ini terdiri daripada sumber primer seperti statut, Arahan-Arahan Amalan, penghakiman kes-kes, temubual dan sumber sekunder seperti penulisan di dalam artikel jurnal dan buku. Analisis kandungan secara deskriptif digunakan bagi menganalisis data-data yang telah dikumpulkan. Kajian ini mendapati pemakaian Arahan Amalan menyediakan garis panduan kepada pegawai sulh dan hakim syarie menjalankan tugas mereka secara berkesan. Namun melalui analisis penghakiman kes yang diputuskan, Arahan Amalan ke arah pemerkasaan pelaksanaan sulh khususnya dalam penyelesaian kes hartanah masih perlu ditambah baik dalam mendepani cabaran semasa, isu perundangan dan pentadbiran. Implikasi kajian ini dapat memantapkan aspek proses penghakiman dan pengurusan kes dalam Mahkamah Syariah di Malaysia. ABSTRACT The application of practice directions assists the implementation of sulh in the Syariah Courts in the preparation of work processes starting from case registration until the issuance of consent judgement order. This study examined the position and application of practice directions in the implementation of sulh with regard to real estate in the Syariah Courts. The data of this study was based on primary sources such as statutes, practice directions, judgement of cases, interviews and secondary sources such as journal articles and books. Descriptive content analysis was used to analyze the data collected. This study found that the application of practice directions serves as guidelines for sulh officers and syarie judges to conduct their duties effectively. Despite this, by using content analysis of the case decided, it was found that practice directions in empowering sulh implementation needs to be improved to deal with current challenges, including legal and administrative issues. The implications of this study can help strengthen aspects of judgement and case management processes in the Malaysian Syariah Courts.
PEMBAYARAN NAFKAH ANAK MELALUI POTONGAN KUMPULAN WANG SIMPANAN PEKERJA: SUATU ALTERNATIF
Authors: Mat Hussin Mohd. Norhusairi , Fauzi Muhammad Farid Aizat 
Published: January 2023

Nafkah anak merupakan suatu kefarduan yang wajib ditunaikan secara berterusan oleh bapa atau penjaga menurut hukum syarak dan undang-undang. Namun begitu, tidak dinafikan bahawa wujudnya pengabaian nafkah daripada pihak bapa kepada anak-anak disebabkan pelbagai faktor. Pengabaian nafkah ini menyebabkan kehidupan anak-anak terjejas dan tidak mendapat hak yang sepatutnya. Oleh itu, kajian ini bertujuan untuk menganalisis potongan Kumpulan Wang Simpanan Pekerja (KWSP) sebagai suatu alternatif untuk pembayaran nafkah anak di Mahkamah Syariah sekaligus mencadangkan potongan simpanan KWSP bapa sebagai salah satu mekanisma pembayaran nafkah. Data utama dalam kajian ini diperolehi melalui kajian perpustakaan dan juga kajian lapangan yang melibatkan temubual dengan Peguam Syarie bagi mendapatkan pandangan mereka berkenaan kaedah-kaedah pembayaran nafkah yang sedia ada serta keperluan pelaksanaan potongan KWSP sebagai kaedah alternatif. Metodologi yang digunakan ini boleh menyoroti potongan wang KWSP bagi tujuan nafkah dibuat melalui undang-undang seterusnya boleh mengesahkan kepentingan potongan wang KWSP bagi membela hak anak-anak untuk mendapatkan nafkah. Kajian ini penting khususnya kepada pihak kerajaan dan pembuat dasar di KWSP bagi meminda dasar yang sedia ada untuk membantu memelihara hak anak-anak daripada sikap culas bapa yang mencarum di KWSP. ABSTRACT Child support is an obligation that must be fulfilled continuously by the father or the guardian according to the Syarak and common law. However, there is no denying that there is often the issue of neglect in the maintenance of child support from the father due to various factors. This neglect has certainly affected the lives of the children as they do not get the rights that they deserve. Therefore, this study aims to analyze the deduction from the Employees Provident Fund (EPF) as an alternative for the payment of child support in the Shariah Court. It is a proposal that the deduction of the father’s EPF savings can be one of the payment mechanisms for child support. The main data in this study was obtained through a library study and also a field study involving interviews with Sharie Counsel. The latter was carried out to obtain their views on the existing methods of payment for child support and the need to implement EPF deductions as an alternative method. The methodology used can highlight the deduction of EPF money for the purpose of child support made through the law. It will also further underscore the importance of the deduction of EPF money to protect the rights of children to obtain child support. This study is important to the government and policy makers as the amendment to the existing policy will go a long way to help protect the rights of children from the cavalier attitude of fathers toward payment for child support.
Diseño y validación de un instrumento para medir la percepción sobre la gestión de residuos sólidos de construcción en las empresas de la ciudad de Cuenca 2021
Authors: Cajamarca-Solis Diego , Heras-Benavides Diego , Mendoza-Enríquez Nayra 
Published: February 2023

Una correcta gestión de residuos sólidos y de desperdicios producidos por las diferentes industrias reduce significativamente el impacto al medio ambiente y protege al entorno. Procesos normativos, tecnológicos y políticas ambientales relacionadas con el manejo de residuos se han desarrollado e implementado escasamente en los proyectos de construcción. En Cuenca, si bien procesos de gestión son aplicados, no existe una herramienta que permita valorar el nivel de percepción asociado a la gestión de residuos sólidos en empresas constructoras de la ciudad.
Objetivo: Esta investigación diseñó un instrumento para medir la percepción en la gestión de residuos sólidos de construcción en las empresas de la ciudad de Cuenca.
Método: Este estudio adoptó un enfoque cuantitativo y se apoyó del diseño observacional. Una propuesta de encuesta fue evaluada por un grupo de expertos, para luego ser aplicada a profesionales constructores. Los datos obtenidos fueron sometidos a validación estadística utilizando los softwares JAMOVI y JASP consiguiendo así una escala validada.
Resultado: Se estableció un instrumento final tipo escala, conformado por diez ítems y distribuido en tres dimensiones: el conocimiento e identificación de residuos sólidos (CIRS), la gestión de residuos de la construcción (GRC) y los efectos de los residuos de construcción (ERC).
Conclusiones: La escala permite medir la situación de la gestión de residuos de una empresa con un nivel aceptable de confiabilidad y validez. Procesos de: optimización, toma de decisiones y mejora continua se derivarán de la información proporcionada por el instrumento.
Monitorização do nível de consciência utilizando o índice biespectral e espectrograma em uma paciente portadora da síndrome do encarceramento sob anestesia geral: um relato de caso
Authors: Dias Gustavo Henrique dos Santos , Oliveira Nádia Marisa Sotério de 
Published: January 2023

Introdução: A síndrome do encarceramento é uma condição neurológica na qual o paciente desenvolve tetraplegia e anartria, se tornando incapaz de executar movimentos dos membros e falar, porém, mantém preservada a propriocepção e a consciência, além do movimento vertical dos olhos, sendo este o único modo do paciente se comunicar. Dentre os vários tipos de monitorizações intraoperatórias, o BIS e o espectrograma nos fornecem a análise do nível de consciência do paciente, permitindo a manutenção de um plano anestésico adequado, reduzindo o despertar intraoperatório e as complicações de um plano anestésico muito profundo. Objetivo: Descrever um caso de uma paciente que desenvolveu a síndrome do encarceramento devido acidente vascular isquêmico de ponte e foi submetida à anestesia geral com monitorização de nível de consciência com o índice bispectral (BIS) e espectrograma. Relato de caso: Paciente de 50 anos, sexo feminino, dona de casa, deu entrada na emergência da UPA São Sebastião - Brasília DF, com quadro de rebaixamento de nível de consciência. Filha relata que paciente referiu queixa de cefaléia intensa, seguida de síncope. Foi avaliada pela equipe médica que optou por intubação orotraqueal e transferiu para serviço de referência em neurologia pela suspeita de AVE. Conclusão: Apesar do estado aparente de coma, o paciente portador da síndrome do encarceramento apresenta dados de monitorização de profundidade anestésica com BIS e espectograma similares à população normal, o que torna seu uso importante na prevenção de desfechos negativos, como a consciência intraoperatória.
Análise de alterações na pele devido ao uso de máscaras em profissionais da saúde
Authors: Colet Thaís Lorenzzon , Mattos Alexandra Brugnera Nunes de 
Published: January 2023

A COVID-19 é uma doença ocasionada pelo vírus SARS-CoV-2 e possui uma alta incidência de propagação, haja vista que sua principal forma de contágio se dá pela disseminação de pequenas partículas virais, os aerossóis. Por isso, como medida de controle do avanço da pandemia, diversas instituições governamentais estabeleceram o uso da máscara de proteção facial como obrigatoriedade, estimulando seu uso por grandes períodos e com abundante frequência. Diante disso, este estudo descritivo tem por objetivo a identificação de alterações tegumentares geradas pelo uso prolongado de máscaras pelos profissionais de saúde, bem como revelar quais são os principais fatores desencadeantes e que interferem nestas afecções. A partir disso, a pesquisa terá como metodologia a aplicação de um questionário online, a fim de obter dados quantitativos para análise de alterações cutâneas, suas causas, e de cuidados que podem ser adotados para evitar o surgimento de dermatoses ocupacionais. Verificou- se que o microclima da pele tem um papel fundamental na manutenção da permeabilidade e na ação antimicrobiana cutânea. Os fatores externos e genéticos, como o ambiente, a temperatura e o pH são meios que influenciam na barreira cutânea. O trabalho aponta que os principais fatores de risco associados ao surgimento de alterações de pele devido ao uso da máscara são a, duração de uso superior a 8 horas por dia, as máscaras do tipo N95/PFF2 e sexo feminino, bem como as dermatoses mais prevalentes dentre a população estudada foram acne e dermatite de contato.
Produção in vitro de embriões partenogenéticos a partir de oócitos caprinos criopreservados: revisão de literatura
Authors: Oliveira Marlene Sipaúba de , Teixeira Letícia Soares de Araújo , Porfírio Kenney de Paiva , Salgueiro Cristiane Clemente de Mello , Nunes Jose Ferreira , Mineiro Ana Lys Bezerra Barradas , Cardoso Janaina de Fátima Saraiva , Paula Ney Rômulo Oliveira 
Published: January 2023

A produção in vitro de embriões (PIV) é uma biotécnica utilizada, alternativamente, para acelerar a produção de animais geneticamente superiores, com diferentes etapas: colheita e maturação in vitro (MIV) de oócitos, fecundação in vitro (FIV), cultivo in vitro (CIV) de zigotos até ao estádio de blastocisto. A PIV, em conjunto com a criopreservação de oócitos e embriões, pode permitir a comercialização de embriões em larga escala, o transporte de embriões livres de patógenos e transações comerciais de germoplasma mais fáceis e baixos custos. Porém, não é efetivo devido a vários fatores relacionados a evolução no processo. Estudos visam facilitar o uso de oócitos por razões biológicas, comerciais e melhor aproveitamento celular. Foi realizada uma revisão narrativa da literatura, por meio de artigos científicos, dissertações, teses e livros publicados nas bases de dados: Scopus, PubMed, Scielo e Google acadêmico, com o objetivo de fornecer uma perspectiva geral dessa biotécnica em caprinos com ênfase na descrição enfatizando as principais metodologias atualmente utilizadas para colheita de oócitos, MIV, FIV e CIV de embriões.
Cuidados ao paciente com câncer: desafios e condutas da enfermagem
Authors: Silva Larissa Gabriele Farias e , Gonçalves Maria Vilmara Batista , Gonçalves Maria Valbilene , Nascimento Maria do Desterro Silva , Conrado Gilceane Maria , Paiva Claudeir Siqueira de , Dias Joseana de Almeida , Souza Lindiclea Balbino de , Silva Maria Aparecida Guimarães da , Couto Sabrina Iracema da Silva 
Published: January 2023

Objetivo: Descrever com base na literatura científica as condutas e dificuldades do enfermeiro diante o paciente oncológico. Metodologia: Trata-se de uma Revisão integrativa da literatura, realizada nos meses de setembro a outubro de 2022, tendo como base de dados: LILACS, SCIELO, PUBMED, contempladas pela BVS, onde foram utilizados artigos na língua portuguesa ou inglesa. Resultados: Foram encontrados 1720 artigos no total, após rigor metodológico por meio dos critérios de inclusão e exclusão, foram selecionados 11 artigos, sendo 5 artigos na LILACS, 3 na SCIELO e 3 na PUBMED, logo após criteriosa avaliação dos artigos, a análise foi feita de forma descritiva e predispõe a extração dos seguintes dados: ano de publicação, autores, título e objetivo, onde todos os artigos evidenciam a importância do cuidado de enfermagem, no suporte emocional ao paciente oncológico e em cuidado paliativos. Conclusão: Portanto, foi possível observar a importância da comunicação entre o profissional de enfermagem e o paciente, além do cuidado estendido para os familiares e o próprio profissional, visto que o mesmo profissional que cuida tem necessidades de ser cuidado. Sendo primordial a equipe de enfermagem assistenciar o paciente e família de forma holística, não focando somente na doença, como já citado, porém deve-se sempre ter em mente que as pessoas são seres biopsicossociais e têm variadas demandas nos âmbitos de suas vidas.
Clinical usefulness of NGS multi-gene panel testing in hereditary cancer analysis
Authors: Anaclerio Federico , Pilenzi Lucrezia , Dell’Elice Anastasia , Ferrante Rossella , Grossi Simona , Ferlito Luca Maria , Marinelli Camilla , Gildetti Simona , Calabrese Giuseppe , Stuppia Liborio , Antonucci Ivana 
Published: February 2023

Introduction: A considerable number of families with pedigrees suggestive of a Mendelian form of Breast Cancer (BC), Ovarian Cancer (OC), or Pancreatic Cancer (PC) do not show detectable BRCA1/2 mutations after genetic testing. The use of multi-gene hereditary cancer panels increases the possibility to identify individuals with cancer predisposing gene variants. Our study was aimed to evaluate the increase in the detection rate of pathogenic mutations in BC, OC, and PC patients when using a multi-gene panel.Methods: 546 patients affected by BC (423), PC (64), or OC (59) entered the study from January 2020 to December 2021. For BC patients, inclusion criteria were i) positive cancer family background, ii) early onset, and iii) triple negative BC. PC patients were enrolled when affected by metastatic cancer, while OC patients were all submitted to genetic testing without selection. The patients were tested using a Next-Generation Sequencing (NGS) panel containing 25 genes in addition to BRCA1/2.Results: Forty-four out of 546 patients (8%) carried germline pathogenic/likely pathogenic variants (PV/LPV) on BRCA1/2 genes, and 46 (8%) presented PV or LPV in other susceptibility genes.Discussion: Our findings demonstrate the utility of expanded panel testing in patients with suspected hereditary cancer syndromes, since this approach increased the mutation detection rate of 15% in PC, 8% in BC and 5% in OC cases. In absence of multi-gene panel analysis, a considerable percentage of mutations would have been lost.
Exome-wide analysis identify multiple variations in olfactory receptor genes (OR12D2 and OR5V1) associated with autism spectrum disorder in Saudi females
Authors: Almandil Noor B. , Alismail Maram Adnan , Alsuwat Hind Saleh , AlSulaiman Abdulla , AbdulAzeez Sayed , Borgio J. Francis 
Published: February 2023

BackgroundAutism Spectrum Disorder (ASD) is a multifactorial, neurodevelopmental disorder, characterized by deficits in communication, restricted and repetitive behaviors. ASD is highly heritable in Saudi Arabia; indecencies of affected individuals are increasing.ObjectivesTo identify the most significant genes and SNPs associated with the increased risk of ASD in Saudi females to give an insight for early diagnosis.MethodsPilot case–control study mostly emphasized on the significant SNPs and haplotypes contributing to Saudi females with ASD patients (n = 22) compared to controls (n = 51) without ASD. With the use of allelic association analysis tools, 243,345 SNPs were studied systematically and classified according to their significant association. The significant SNPs and their genes were selected for further investigation for mapping of ASD candidate causal variants and functional impact.ResultsIn females, five risk SNPs at p ≤ 2.32 × 10−05 was identified in association with autism. The most significant exonic variants at chromosome 6p22.1 with olfactory receptor genes (OR12D2 and OR5V1) clustered with high linkage disequilibrium through haplotyping analysis. Comparison between highly associated genes (56 genes) of male and female autistic patients with female autistic samples revealed that 39 genes are unique biomarkers for Saudi females with ASD.ConclusionMultiple variations in olfactory receptor genes (OR5V1 and OR12D2) and single variations on SPHK1, PLCL2, AKAP9 and LOC107984893 genes are contributing to ASD in females of Arab origin. Accumulation of these multiple predisposed coding SNPs can increase the possibility of developing ASD in Saudi females.
Effect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials
Authors: Abedi Ali , Ghobadi Hassan , Sharghi Afshan , Iranpour Sohrab , Fazlzadeh Mehdi , Aslani Mohammad Reza 
Published: February 2023

IntroductionThis study aimed to perform an updated systematic review and meta-analysis to evaluate the effectiveness of saffron supplementation on oxidative stress markers [malondialdehyde (MDA), total antioxidant capacity (TAC), total oxidant status (TOS), glutathione peroxidase (GPx), superoxide dismutase (SOD), and prooxidant/antioxidant balance (PAB)] in randomized controlled trials (RCTs).MethodsWe searched PubMed/Medline, Web of Science, Scopus, Cochrane CENTRAL, and Google Scholar until December 2022. Trial studies investigating the effects of oral saffron supplements on MDA, TAC, TOS, GPx, SOD, and PAB concentrations were included in the study. To analyze the results, mean differences (SMD) and 95% confidence intervals (CI) were pooled using a random effects model. Heterogeneity was assessed using the Cochrane Q and I2 values. Sixteen cases were included in the meta-analysis (468 and 466 subjects in the saffron and control groups, respectively).ResultsIt was found that saffron consumption caused a significant decrease in MDA (SMD: −0.322; 95% CI: −0.53, −0.16; I2 = 32.58%) and TOS (SMD: −0.654; 95% CI: −1.08, −0.23; I2 = 68%) levels as well as a significant increase in TAC (SMD: 0.302; 95% CI: 0.13, 0.47; I2 = 10.12%) and GPx (SMD: 0.447; 95% CI: 0.10, 0.80; I2 = 35%). Subgroup analysis demonstrated a significant reduction in MDA levels in studies with a saffron dosage of &gt;30 mg/day, age of &lt;50 years, and study duration of &lt;12 weeks. Among the limitations of the study, we can point out that the studies were from Iran, the different nature of the diseases included, and were not considered of some potential confounders such as smoking, physical activity, and diet in the studies.DiscussionIn summary, the results showed that saffron has beneficial effects on oxidative stress markers.
Pediococcus pentosaceus PR-1 modulates high-fat-died-induced alterations in gut microbiota, inflammation, and lipid metabolism in zebrafish
Authors: Liu Yue , Zhu Danxu , Liu Jiwen , Sun Xiaoxia , Gao Feng , Duan Huiping , Dong Lina , Wang Xin , Wu Changxin 
Published: February 2023

IntroductionObesity is a health issue worldwide. This study aimed to evaluate the beneficial effects of Pediococcus pentococcus PR-1 on the modulating of gut microbiota, inflammation and lipid metabolism in high-fat-diet (HFD)-fed zebrafish.MethodsAdult zebrafish were fed a commercial (C), high fat (H, 25% fat), probiotic (P, 106 CFU/g), or high fat with probiotic (HP) diets twice daily for 5 weeks. Gut microbiota were analysed using 16S rRNA gene sequencing. Gene expressions of intestinal cytokine, intestinal TJ protein, and liver lipid metabolism were analysed by quantitative real-time polymerase chain reaction. Biochemical and histological analysis were also performed.Results and discussionP. pentosaceus PR-1 reduced body weight and BMI, indicating its anti-obesity effect. The 16S rRNA sequencing results showed HFD induced a distinct gut microbiota structure from C group, which was restored by probiotic. P. pentosaceus PR-1 improved gut health by decreasing the abundance of Ralstonia and Aeromonas which were increased induced by HFD. Moreover, probiotic restored abundance of Fusobacteria, Cetobacterium and Plesiomonas, which were decreased in HFD-fed zebrafish. The results of quantitative real-time polymerase chain reaction showed probiotic suppressed HFD-induced inflammation by decreasing the expressions of IL-1b and IL-6. Levels of hepatic TNF-α, IL-1ß, and IL-6 were reduced by probiotic in HFD-fed zebrafish. Probiotic also ameliorated gut barrier function by increasing the expressions of occludin, Claudin-1, and ZO-1. Probiotic exerted anti-adipogenic activity through regulating the expressions of SREBP1, FAS and LEPTIN. Levels of hepatic triglyceride, total cholesterol, low density lipoprotein were also reduced by probiotic. Histological analysis showed probiotic alleviated liver steatosis and injury induced by HFD. P. pentosaceus PR-1 might be useful as a dietary health supplement, especially for reducing obesity.