bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constraints on the Hubble constant from supernova Refsdal’s reappearance
Authors: Kelly Patrick L. , Rodney Steven , Treu Tommaso , Oguri Masamune , Chen Wenlei , Zitrin Adi , Birrer Simon , Bonvin Vivien , Dessart Luc , Diego Jose M. , Filippenko Alexei V. , Foley Ryan J. , Gilman Daniel , Hjorth Jens , Jauzac Mathilde , Mandel Kaisey , Millon Martin , Pierel Justin , Sharon Keren , Thorp Stephen , Williams Liliya , Broadhurst Tom , Dressler Alan , Graur Or , Jha Saurabh , McCully Curtis , Postman Marc , Schmidt Kasper Borello , Tucker Brad E. , von der Linden Anja 
Published: May 2023

The gravitationally lensed supernova Refsdal appeared in multiple images produced through gravitational lensing by a massive foreground galaxy cluster. After the supernova appeared in 2014, lens models of the galaxy cluster predicted that an additional image of the supernova would appear in 2015, which was subsequently observed. We use the time delays between the images to perform a blinded measurement of the expansion rate of the Universe, quantified by the Hubble constant (
H
0
). Using eight cluster lens models, we infer

H
0

=

64.8

−
4.3

+
4.4

kilometers per second per megaparsec

. Using the two models most consistent with the observations, we find

H
0

=

66.6

−
3.3

+
4.1

kilometers per second per megaparsec

. The observations are best reproduced by models that assign dark-matter halos to individual galaxies and the overall cluster.
Effect of resistance exercise dose components for tendinopathy management: a systematic review with meta-analysis
Authors: Pavlova Anastasia Vladimirovna , Shim Joanna S C , Moss Rachel , Maclean Colin , Brandie David , Mitchell Laura , Greig Leon , Parkinson Eva , Alexander Lyndsay , Tzortziou Brown Victoria , Morrissey Dylan , Cooper Kay , Swinton Paul A 
Published: May 2023

ObjectiveTo investigate potential moderating effects of resistance exercise dose components including intensity, volume and frequency, for the management of common tendinopathies.DesignSystematic review with meta-analysis and meta-regressions.Data sourcesIncluding but not limited to: MEDLINE, CINAHL, SPORTDiscus, ClinicalTrials.gov and ISRCTN Registry.Eligibility criteria for selecting studiesRandomised and non-randomised controlled trials investigating resistance exercise as the dominant treatment class, reporting sufficient information regarding ≥2 components of exercise dose.ResultsA total of 110 studies were included in meta-analyses (148 treatment arms (TAs), 3953 participants), reporting on five tendinopathy locations (rotator cuff: 48 TAs; Achilles: 43 TAs; lateral elbow: 29 TAs; patellar: 24 TAs; gluteal: 4 TAs). Meta-regressions provided consistent evidence of greater pooled mean effect sizes for higher intensity therapies comprising additional external resistance compared with body mass only (large effect size domains:βBodyMass: External= 0.50 (95% credible interval (CrI): 0.15 to 0.84; p=0.998); small effect size domains (βBodyMass: External= 0.04 (95% CrI: −0.21 to 0.31; p=0.619)) when combined across tendinopathy locations or analysed separately. Greater pooled mean effect sizes were also identified for the lowest frequency (less than daily) compared with mid (daily) and high frequencies (more than once per day) for both effect size domains when combined or analysed separately (p≥0.976). Evidence for associations between training volume and pooled mean effect sizes was minimal and inconsistent.Summary/conclusionResistance exercise dose is poorly reported within tendinopathy management literature. However, this large meta-analysis identified some consistent patterns indicating greater efficacy on average with therapies prescribing higher intensities (through inclusion of additional loads) and lower frequencies, potentially creating stronger stimuli and facilitating adequate recovery.
Factors associated with viral load non-suppression in people living with HIV on ART in Nigeria: cross-sectional analysis from 2017 to 2021
Authors: Tomescu Silviu , Crompton Thomas , Adebayo Jonathan , Akpan Francis , Dauda Dauda Sulaiman , Allen Zola , Ondura Evans Odhiambo , Wose Kinge Constance , Chasela Charles , Pisa Pedro 
Published: May 2023

ObjectivesIdentify factors (demographic and clinical) associated with a non-suppressed viral load (VL) of people living with HIV (PLHIV) on antiretroviral therapy (ART) in Nigeria.DesignCross-sectional study.SettingSixteen US Agency for International Development supported states in Nigeria.Participants585 632 PLHIV on ART.Primary outcome measuresVL non-suppression (defined as having a VL of at least 1000 HIV RNA copies per mL of plasma). χ2testing and multivariable modified Poisson regression with robust variance estimates were conducted on routinely collected ART programme data.ResultsSixty-six per cent of the study population were females. The largest age groups were 25–34 and 35–44, accounting for 32.1% and 31.1%, respectively. Males had a 9% greater likelihood (adjusted prevalence ratio, APR=1.09) of being non-suppressed. The age groups below 60+ (APR=0.67) had a higher likelihood of a non-suppressed VL, with the highest in the 0–14 age group (APR=2.38). Clients enrolled at tertiary and secondary level facilities had the greatest likelihood of a non-suppressed VL. Clients who started ART between 2010 and 2015 had the greatest likelihood of viral non-suppression (APR=6.19). A shorter time on ART (<1 year (APR=3.92)) was associated with a higher likelihood of a non-suppressed VL. Clients receiving care at private facilities had a lower likelihood of viral non-suppression in the adjusted model. Clients in the Edo (APR=2.66) and Niger (APR=2.54) states had the greatest likelihood of viral non-suppression.ConclusionsTargeting males, clients of younger age, those on treatment for less than 3 years, clients at tertiary and secondary health facilities, small and medium facilities, and clients in the Edo, Niger and Borno states for interventions could lead to improvements in VL suppression in Nigeria. The independent factors associated with a non-suppressed VL can guide improvements in ART programme development and VL suppression of PLHIV on ART in Nigeria.
Efficacy and safety of acupuncture for post-COVID-19 depression: a protocol for systematic review and meta-analysis
Authors: Li Bei , Liu Haijing , Luo Xin , Liu Yuhua , Pan Jin , Yang Meidi , Tian Hangcheng , Hu Chi , Feng Yang , Li Cuiling 
Published: May 2023

IntroductionPost-COVID-19 depression (PCD) is a possible sequela of COVID-19. Some doctors have used acupuncture to treat PCD, but no systematic review or meta-analysis has yet evaluated its efficacy and safety for the treatment of PCD. The aim of this systematic review is to assess the efficacy and safety of acupuncture therapy for PCD.Methods and analysisTwo reviewers will independently search the Cochrane Central Register of Controlled Trials (CENTRAL), Medline (PubMed), Excerpt Medica Database (EMBASE), China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Chinese Scientiﬁc Journal Database (VIP) and Wan-Fang Database from inception to 24 January 2023. Study selection, data extraction and assessment of study quality will be independently performed by two reviewers. If a meta-analysis is appropriate, Review Manager V.5.3 will be used for data synthesis; otherwise, a descriptive analysis will be conducted. Data will be synthesised using a ﬁxed-effects or random-effects model, according to the results of a heterogeneity test. The results will be presented as risk ratios with 95% CIs for dichotomous data, and weighted mean differences or standardised mean differences with 95% CIs for continuous data.Ethics and disseminationThe entire process used for this systematic review does not use private information, so ethical approval is not required. The results of this meta-analysis will be disseminated through publication in a peer-reviewed journal and/or conference presentations.PROSPERO registration numberCRD42022379312.
Feasibility randomised controlled trial of online group Acceptance and Commitment Therapy for Functional Cognitive Disorder (ACT4FCD)
Authors: Poole Norman , Cope Sarah , Vanzan Serena , Duffus Aimee , Mantovani Nadia , Smith Jared , Barrett Barbara M , Tokley Melanie , Scicluna Martin , Beardmore Sarah , Turner Kati , Edwards Mark , Howard Robert 
Published: May 2023

IntroductionFunctional cognitive disorder (FCD) is seen increasingly in clinics commissioned to assess cognitive disorders. Patients report frequent cognitive, especially memory, failures. The diagnosis can be made clinically, and unnecessary investigations avoided. While there is some evidence that psychological treatments can be helpful, they are not routinely available. Therefore, we have developed a brief psychological intervention using the principles of acceptance and commitment therapy (ACT) that can be delivered in groups and online. We are conducting a feasibility study to assess whether the intervention can be delivered within a randomised controlled trial. We aim to study the feasibility of recruitment, willingness to be randomised to intervention or control condition, adherence to the intervention, completion of outcome measures and acceptability of treatment.Methods and analysisWe aim to recruit 48 participants randomised 50:50 to either the ACT intervention and treatment as usual (TAU), or TAU alone. ACT will be provided to participants in the treatment arm following completion of baseline outcome measures. Completion of these outcome measures will be repeated at 8, 16 and 26 weeks. The measures will assess several domains including psychological flexibility, subjective cognitive symptoms, mood and anxiety, health-related quality of life and functioning, healthcare utilisation, and satisfaction with care and participant-rated improvement. Fifteen participants will be selected for in-depth qualitative interviews about their experiences of living with FCD and of the ACT intervention.Ethics and disseminationThe study received a favourable opinion from the South East Scotland Research Ethics Committee 02 on 30 September 2022 (REC reference: 22/SS/0059). HRA approval was received on 1 November 2022 (IRAS 313730). The results will be published in full in an open-access journal.Trial registration numberISRCTN12939037.
New perspective on exploring the predictive factors of blood pressure reduction during CPAP treatment in people with severe OSA and hypertension: a prospective observational study
Authors: Meng Zili , Chen Ying , Yang Ting , Sun Bo , Luo Chao , Wei Guihong , Xie Xiaochen , Gu Yang , Ding Ning , Zhang Xilong , Xu Jing 
Published: May 2023

BackgroundThe predictive factors of blood pressure (BP) response to continuous positive airway pressure (CPAP) in obstructive sleep apnoea (OSA) are still being explored. We aimed to assess the antihypertensive effect of CPAP considering the obstructive respiratory event-triggered BP surge profiles in 130 subjects with severe OSA and untreated hypertension.MethodsNocturnal BP was monitored continuously and synchronised with polysomnography. Event-triggered BP surge profiles were studied: BP surge as the value of event-related systolic BP (SBP) elevation; BP index as the number of BP surge events of ≥10 mm Hg per hour. Patients were then divided into two groups according to the median BP index (high and low BP surge groups) and assigned to 4 weeks of CPAP. Changes in BPs and plasma biomarkers were compared. After the initial evaluation, patients with a better BP response in the high BP surge group were then followed up for the second evaluation at 24 months.ResultsOverall, a modest decrease was observed in both office and asleep BPs at the 4-week follow-up; however, BPs dropped more markedly in patients in the high BP surge group than those in the low BP surge group, in both office SBP (5.3 mm Hg vs 2.2 mm Hg, p=0.003) and diastolic BP (4.0 mm Hg vs 1.2 mm Hg, p<0.001), especially the asleep SBP (9.0 mm Hg vs 2.1 mm Hg, p<0.001). For 30 cases in the high BP surge group, optimal BP control was achieved in 60.0% of patients and BP<140/90 mm Hg reached up to 83.3% after 24 months of CPAP. Linear regression revealed that BP index was significantly associated with BP decrease during CPAP treatment.ConclusionsOur results suggested that high event-triggered BP surge was a sensitive predictor of BP response to CPAP in patients with severe OSA and untreated hypertension.Trial registration numberClinical Trials.gov Identifier:NCT03246022;https://clinicaltrials.gov/ct2/show/NCT03246022?term=NCT+03246022&draw=2&rank=1.
Distinguishing functional from primary tics: a study of expert video assessments
Authors: Rigas Antigony , Mainka Tina , Pringsheim Tamara , Münchau Alexander , Malaty Irene , Worbe Yulia , Cavanna Andrea E , Lees Andrew John , Lang Anthony E , Martino Davide , Ganos Christos 
Published: May 2023

BackgroundReliably applied criteria to differentiate functional from primary tics are lacking. In the absence of biological markers, the development of new diagnostic criteria to assist clinicians is predicated on expert judgement and consensus. This study examines the level of diagnostic agreement of experts in tic disorders using video footage and clinical descriptions.MethodsUsing a two-part survey, eight experts in the diagnosis and management of tics were first asked to study 24 case videos of adults with primary tics, functional tics or both and to select a corresponding diagnosis. In the second part of the survey, additional clinical information was provided, and the diagnosis was then reconsidered. Inter-rater agreement was measured using Fleiss’ kappa. In both study parts, the factors which influenced diagnostic decision-making and overall diagnostic confidence were reviewed.ResultsBased on phenomenology alone, the diagnostic agreement among the expert raters was only fair for the pooled diagnoses (κ=0.21) as well as specifically for functional (κ=0.26) and primary tics (κ=0.24). Additional clinical information increased overall diagnostic agreement to moderate (κ=0.51) for both functional (κ=0.6) and primary tics (κ=0.57). The main factors informing diagnosis were tic semiology, age at tic onset, presence of premonitory urges, tic suppressibility, the temporal latency between tic onset and peak severity, precipitants and tic triggers and changes in the overall phenotypic presentation.ConclusionsThis study confirmed that in the absence of clinical information, the diagnostic distinction between primary and functional tics is often difficult, even for expert clinicians.
Determinants and clinical outcomes of patients who refused anticoagulation: findings from the global GARFIELD-AF registry
Authors: Apenteng Patricia , Virdone Saverio , Camm John , Fox Keith A A , Bassand Jean-Pierre , Turpie Alexander G G , Oh Seil , Brodmann Marianne , Cools Frank , Barretto Antonio C P , Nielsen Jørn , Haas Sylvia , Kayani Gloria , Pieper Karen S , Kakkar Ajay K 
Published: May 2023

ObjectiveThere is a substantial incidence of stroke in patients with atrial fibrillation (AF) not receiving anticoagulation. The reasons for not receiving anticoagulation are generally attributed to clinician’s choice, however, a proportion of AF patients refuse anticoagulation. The aim of our study was to investigate factors associated with patient refusal of anticoagulation and the clinical outcomes in these patients.MethodsOur study population comprised patients in the Global Anticoagulant Registry in the FIELD (GARFIELD-AF) registry with CHA2DS2-VASc≥2. A logistic regression was developed with predictors of patient anticoagulation refusal identified by least absolute shrinkage and selection operator methodology. Patient demographics, medical and cardiovascular history, lifestyle factors, vital signs (body mass index, pulse, systolic and diastolic blood pressure), type of AF and care setting at diagnosis were considered as potential predictors. We also investigated 2-year outcomes of non-haemorrhagic stroke/systemic embolism (SE), major bleeding and all-cause mortality in patients who refused versus patients who received and patients who did not receive anticoagulation for other reasons.ResultsOut of 43 154 AF patients, who were at high risk of stroke, 13 283 (30.8%) did not receive anticoagulation at baseline. The reason for not receiving anticoagulation was unavailable for 38.7% (5146/13 283); of the patients with a known reason for not receiving anticoagulation, 12.5% (1014/8137) refused anticoagulation. Diagnosis in primary care/general practitioner, Asian ethnicity and presence of vascular disease were strongly associated with a higher risk of patient refusal of anticoagulation. Patient refusal of anticoagulation was associated with a higher risk of non-haemorrhagic stroke/SE (adjusted HR (aHR) 1.16 (95% CI 0.77 to 1.76)) but lower all-cause mortality (aHR 0.59 (95% CI 0.43 to 0.80)) compared with patients who received anticoagulation. The GARFIELD-AF mortality score corroborated this result.ConclusionThe data suggest patient refusal of anticoagulation is a missed opportunity to prevent AF-related stroke. Further research is required to understand the patient profile and mortality outcome of patients who refuse anticoagulation.
Feasibility study of using bench-scale centrifugation for segregation and consolidation behaviour of oil sands tailings products
Authors: Wong Chee K. , Hu Tianquan , Graham Michael , Wong Ron C.K. 
Published: May 2023

Fluid fine tailings (FFT) are a by-product of the process used to extract bitumen from surface-mined oil sands in Alberta, Canada. One of the FFT reclamation techniques involves mixing centrifuged FFT with coarse sand tailings to form non-segregating tailings (NST). While NST provides a means to achieve mine closure and reclamation objectives, the self-weight consolidation of NST takes years to complete in full-scale testing. This paper examines the use of bench-scale centrifugation for physical modelling of the consolidation of NST under centrifuge loading. A series of bench-scale centrifuge tests is conducted on NST specimens reconstituted at different sand–fines ratios (SFRs), along with conventional oedometer and standpipe tests. Micro-computed tomography technique with high resolution is used to quantify the internal structure of the centrifuged specimens, and to infer the segregation and consolidation behaviour of NST specimens under 1-g and centrifuge loading. No segregation is detected in NST specimens under 1-g loading, while segregation occurs in NST specimens with low SFRs under centrifugal loading. Thus, only consolidation behaviour of NST specimens without segregation is investigated and compared to those determined from conventional oedometer tests. Limitations on use of bench-scale centrifuge in physical modelling of consolidation behaviour of oil sands tailings are addressed.
Research status and emerging trends in remediation of contaminated sites: a bibliometric network analysis
Authors: Cui Wenwen , Dong Xiaoqiang , Li Xiaoqiang , Zhang Jieya , Lu Yisi , Yang Fan 
Published: May 2023

Site contamination poses a grave danger to the environmental quality and human health, and its remediation has been a focus of worldwide concern over the last few decades. Based on 5068 bibliographic data (2001–2022) acquired from the Web of Science Core Collection, this study employed a scientometric analysis approach to analyze the present state and investigate the trends of contaminated site remediation studies. The results of this study provide an in-depth response to the following: (1) publication characteristics of polluted site restoration studies; (2) basic information on countries, institutions, journals, and disciplines engaged in remediation research in contaminated areas; and (3) a summary of development trends and hotspots in poisoned field cleanup investigations. In summary, this study assessed the results of research on contaminated site remediation. Those unfamiliar with contaminated site remediation could utilize the information in this study to rapidly merge into the field and grasp the forefront of research on this subject. This article can be regarded as a reference for scholars who desire to conduct further research on relevant subjects.
New limit on $$^{94}$$Zr double beta decay to the 1st excited state of $$^{94}$$Mo
Authors: Celi E. , Ješkovský M. , Laubenstein M. , Nagorny S. S. , Nahorna V. V. , Nisi S. , Pagnanini L. , Povinec P. , Wang P. 
Published: May 2023

AbstractA new study of double beta decay processes in natural Zr isotopes using Zr metal samples and an ultra-low-background high-purity germanium detectors was performed at Laboratori Nazionali del Gran Sasso of INFN (Italy). Two data sets were collected with a 736.35 g and a 129.94 g Zr metal over 59.7 days and 37.3 days, respectively, and were used for a detailed analysis. A new limit on the double beta decay of $$^{94}$$

94

Zr to the 1st excited level of $$^{94}$$

94

Mo was set as $$T_{1/2}^{\beta \beta } > 2.1\times 10^{20}~\text {year}$$

T

1
/
2

β
β

>
2.1
×

10
20

year

, which is a factor of three better than the previous result. It is shown that the current radiopurity of Zr metal (tens of Bq/kg), produced via two methods, do not comply with the radiopurity requirements for low-background experiments. Hence, we propose to use a purified ZrCl$$_{4}$$

4

powder in an optimized geometry as a new approach for future experiments with extended sensitivity focused on studies of rare nuclear processes in Zr isotopes.
Localization of abelian gauge fields with Stueckelberg-like geometrical coupling on f(T, B)-thick brane
Authors: Belchior F. M. , Moreira A. R. P. , Maluf R. V. , Almeida C. A. S. 
Published: May 2023

AbstractIn the context of f(T, B) modified teleparallel gravity, we investigate the influence of torsion scalar T and boundary term B on the confinement of both the gauge vector and Kalb–Ramond fields. Both fields require a suitable coupling in five-dimensional braneworld scenarios to yield a normalizable zero mode. We propose a Stueckelberg-like geometrical coupling that non-minimally couples the fields to the torsion scalar and boundary term. To set up our braneworld models, we use the first-order formalism in which two kinds of superpotential are taken: sine-Gordon and $$\phi ^{4}$$

ϕ
4

-deformed. The geometrical coupling is used to produce a localized zero mode. Moreover, we analyze the massive spectrum for both fields and obtain possible resonant massive modes. Furthermore, we do not find tachyonic modes leading to a consistent thick brane.
Towards the theory of how a constitutional supercooling layer appears ahead of the planar crystallization front
Authors: Alexandrov Dmitri V. , Toropova Liubov V. 
Published: May 2023

AbstractThis study, the effect of constitutional supercooling appearing ahead of the crystallization front and leading to the mushy layer origination is considered. An approximate analytical theory determining the time of mushy layer initiation is constructed. Theoretical predictions are in good agreement with numerical simulations carried out in previous studies.