bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure Regulation of MOF Nanosheet Membrane for Accurate H2/CO2 Separation
Authors: Song Hongling , Peng Yuan , Wang Chenlu , Shu Lun , Zhu Chenyu , Wang Yanlei , He Hongyan , Yang Weishen 
Published: March 2023

AbstractHigh‐purity H2 production accompanied with a precise decarbonization opens an avenue to approach a carbon‐neutral society. Metal–organic framework nanosheet membranes provide great opportunities for an accurate and fast H2/CO2 separation, CO2 leakage through the membrane interlayer galleries decided the ultimate separation accuracy. Here we introduce low dose amino side groups into the Zn2(benzimidazolate)4 conformation. Physisorbed CO2 served as interlayer linkers, gently regulated and stabilized the interlayer spacing. These evoked a synergistic effect of CO2 adsorption‐assisted molecular sieving and steric hinderance, whilst exquisitely preserving apertures for high‐speed H2 transport. The optimized amino membranes set a new record for ultrathin nanosheet membranes in H2/CO2 separation (mixture separation factor: 1158, H2 permeance: 1417 gas permeation unit). This strategy provides an effective way to customize ultrathin nanosheet membranes with desirable molecular sieving ability.
Hierarchical Microtubular Covalent Organic Frameworks Achieved by COF‐to‐COF Transformation
Authors: Mu Zhenjie , Zhu Yuhao , Zhang Yufeng , Dong Anwang , Xing Chunyan , Niu Ziru , Wang Bo , Feng Xiao 
Published: March 2023

AbstractPore environment and aggregated structure play a vital role in determining the properties of porous materials, especially regarding the mass transfer. Reticular chemistry imparts covalent organic frameworks (COFs) with well‐aligned micro/mesopores, yet constructing hierarchical architectures remains a great challenge. Herein, we reported a COF‐to‐COF transformation methodology to prepare microtubular COFs. In this process, the C3‐symmetric guanidine units decomposed into C2‐symmetric hydrazine units, leading to the crystal transformation of COFs. Moreover, the aggregated structure and conversion degree varied with the reaction time, where the hollow tubular aggregates composed of mixed COF crystals could be obtained. Such hierarchical architecture leads to enhanced mass transfer properties, as proved by the adsorption measurement and chemical catalytic reactions. This self‐template strategy was successfully applied to another four COFs with different building units.
Multiple stories: Collaborative and generative possibilities for psychological evaluation
Authors: Ruiz‐Alfaro Frances , Arandes Edgardo Morales 
Published: March 2023

AbstractThis paper explores a collaborative generative approach to psychological assessment employed in Puerto Rico, with children, adolescents, and adults. It begins with a critical reflection on how the dominant discourse of mental health, founded in the suppositions and practices of Euro‐American‐centred psychological knowledge, has been disseminated to the globalise south under the claim that its assertions are unaffected by social, ideological, or historical forces. It discusses how its claims of expertscientific knowledgehave contributed, through classificatory instruments such as the DSM and the ICD, to the production and re‐production of deficit narratives in our day‐to‐day life. It also examines how these practices have been applied in the use of assessment instruments in Puerto Rico. It then describes, how, through a collaborative approach and narrative theory, the established colonising practices and narratives of traditional forms of psychological assessment can be questioned, deconstructed, and transformed. This approach promotes the co‐creation of dialogic and generative spaces that allow for the emergence of multiple stories and performances that give meaning to a person's identity and relational being. A brief clinical case exposition is used to illustrate how this collaborative, dialogic, and culturally sensitive approach to psychological assessment can help to undermine and disrupt deficit‐based narratives and provide families with new generative possibilities for re‐storying and re‐performing their lives and particularly, the lives of their children.
Evaluation of Terminalia arjuna loaded in surfactant modified polycaprolactone nanofiber as an infection resistant matrix
Authors: Kumari Vandana , Mukhopadhyay Samrat , Gupta Bhuvanesh 
Published: March 2023

AbstractElectrospinning of polycaprolactone (PCL) nanofiber (NF) was carried out with bis (2‐ethylhexyl) sulfosuccinate (AOT) and Triton X 100 (TX 100) surfactants. PCL and surfactant concentration were optimized to get fine NF. The morphological study of the NF was carried out by scanning electron microscope and atomic force microscopy. The structural changes were evaluated by X‐ray diffraction, and its elemental mapping was analyzed by energy dispersive X‐ray mapping. The addition of surfactants altered the morphology of PCL NFs and improved their physiochemical properties, such as wettability, roughness and crystallinity. Among these two surfactants, AOT gave a better NF structure. In the presence of AOT, the hydroalcoholic extract of Terminalia arjuna (TA) was incorporated as the herbal drug, and antibacterial behavior against gram‐positive and gram‐negative bacteria was monitored. The novelty of this work was in the use of a surfactant as a cospinning agent for dual purposes in a single step. The surfactant changed the hydrophobic PCL into a superhydrophilic matrix and incorporated herbal extract to develop an infection‐resistance nanofiber. The developed PCL/TA nanofiber showed excellent potential as an antimicrobial agent with antioxidant properties.
A new genus of Praemordellinae from the Middle Jurassic of China
Authors: Sun Yifei , Du Xuheng , Cao Jiajia , Pang Hong , Bao Tong 
Published: March 2023

AbstractJuramordella asperula gen. et sp. nov. (Coleoptera: Tenebrionoidea) is described based on a specimen from the Middle Jurassic Daohugou Biota, Nincheng County, Inner Mongolia of China. Juramordella asperula is distinguished from other Praemordellinae mainly for roughly punctate elytra, absence of subapical or lateral ridges on all tibiae and tarsi, simple, not bilobed protarsi and mesocoxa distant from procoxa, epicoxa not anterior to metacoxa, well‐developed metafemur and absence of elongated pygidium. The morphology of Juramordella asperula demonstrates the early mordellid‐like beetles have adopted the body shape with their way of movement since the Middle Jurassic, long before their flower‐visiting behavior was established.
Path planning for a tracked robot traversing uneven terrains based on tip‐over stability
Authors: Zhao Jiangbo , Zhang Jiaquan , Liu Hanze , Wang Junzheng , Chen Zhihua 
Published: March 2023

AbstractIn the real‐world environment, the path planning method of tracked robot is widely studied when driving on uneven terrain. How to solve the problem that the traditional path planning algorithm cannot adapt to uneven terrain because of the constraints of obstacle avoidance and path length is a challenge for tracked robots. In this paper, a stability‐based path planning framework for tracked robot is proposed to reduce the risk of rollover when the tracked robot passes through uneven terrain. First, a virtual plane method is proposed to estimate the attitude of tracked robot. Second, on this basis, a dynamic high‐stability path evaluation algorithm for tracked robot based on force angle stability margin (FASM) is proposed, which transforms the stability‐based path planning problem into a hypergraph problem. Moreover, considering that the optimization problem is strongly nonlinear and nonconvex, a hybrid algorithm of covariance matrix adaptive evolution strategy (CMAES) and Levenberg–Marquardt (LM) is designed under the framework of generalized graph optimization (G2O) to improve the solution efficiency. Finally, simulation and experiments show that the stability‐based path planning framework can effectively plan the high‐quality path, and the maximum stability of the tracked robot is 0.9156 when the robot crosses uneven terrain using optimal path 2.
Childhood trauma as a mediator between attachment and recidivism risk: A study of Canadian offenders with mental disorders
Authors: Adams G. Camelia , Wrath Andrew J. , Mela Mansfield , DesRoches Andrea , Adams Stephen , Andreen Anita , McKenna Anne 
Published: March 2023

AbstractThe current study aimed to explore the relationships between attachment and childhood trauma on recidivism risk in a sample of Canadian offenders with mental disorder (OMDs). N = 56 OMDs completed the Adverse Childhood Experiences (ACE) questionnaire, a measure of adult attachment (Experiences in Close Relationships Scale), and interview to determine recidivism risk (Level of Service/Case Management Inventory; LS/CMI). The variables of interest had small to moderate correlations. Multivariable regression analysis found that ACE scores but not attachment insecurity were associated with LS/CMI scores. Mediation analyses demonstrated that ACE scores fully mediated the association between attachment anxiety and attachment avoidance and recidivism risk. Results demonstrate that as exposure to diverse ACEs increased so did the risk to recidivate and this exposure mediated the relationship between attachment insecurity and recidivism risk. This study highlights the necessity of addressing both attachment insecurity and the experience of ACE when providing psychiatric services to OMDs.
Antitumor Cembrane Diterpenoids from the South China Sea Soft Coral Lobophytum sp.
Authors: Song Yu‐Ting , Yu Dan‐Dan , Zhi Su Ming , Luo Hui , Cao Jian‐Guo , Yao Li‐Gong , Liang Lin‐Fu , Guo Yue‐Wei , Yang Fan 
Published: March 2023

AbstractTwo new highly functionalized cembrane diterpenoids named ximaolobophytolides A (1) and B (2) as minor components, together with seven related known compounds (3–9), have been isolated and identified from the Ximao soft coral Lobophytum sp. They were characterized by the presence of an α‐methylene‐γ‐lactone moiety. Based on the comprehensive analyses of 1D and 2D NMR spectroscopic data, the absolute configurations of these two new compounds were elucidated by the combination of quantum mechanical (QM)‐NMR and time‐dependent density functional theory/electronic circular dichroism (TDDFT‐ECD) calculation approaches. In the anti‐tumor bioassays, compounds 3–9 showed moderate to significant inhibitory effects (IC50 values ranging from 29.66 to 0.39 μM) against the proliferations of five tumor cells HEL, A549, H1975, MDA‐MB‐231, and H1299. It might be worthy to point out that compounds 4, 7, and 8 exhibited better anti‐tumor activities than that of the positive control Doxorubicin.
Tracking the Message: Applying Single Molecule Localization Microscopy to Cellular RNA Imaging
Authors: Arnould Benoît , Quillin Alexandria L. , Heemstra Jennifer M. 
Published: March 2023

AbstractRNA function is increasingly appreciated to be more complex than merely communicating between DNA sequence and protein structure. RNA localization has emerged as a key contributor to the intricate roles RNA plays in the cell, and the link between dysregulated spatiotemporal localization and disease warrants an exploration beyond sequence and structure. However, the tools needed to visualize RNA with precise resolution are lacking in comparison to methods available for studying proteins. In the past decade, many techniques have been developed for imaging RNA, and in parallel super resolution and single‐molecule techniques have enabled imaging of single molecules in cells. Of these methods, single molecule localization microscopy (SMLM) has shown significant promise for probing RNA localization. In this review, we highlight current approaches that allow super resolution imaging of specific RNA transcripts and summarize challenges and future opportunities for developing innovative RNA labeling methods that leverage the power of SMLM.
Oligonucleotides Containing C5‐Propynyl Modified Arabinonucleic Acids: Synthesis, Biophysical and Antisense Properties
Authors: Pontarelli Alexander , Wilds Christopher J. 
Published: March 2023

AbstractThe introduction of chemical modifications on the nucleic acid scaffold has allowed for the progress of antisense oligonucleotides (ASOs) in the clinic for the treatment of a variety of disorders. In contribution to the repertoire of gene‐silencing nucleic acid modifications, herein we report the synthesis and incorporation of C5‐propynyl arabinouridine (araUP) and arabinocytidine (araCP) into mixed‐base ASOs containing a pyrimidine core. Substitution of the core with araUP and araCP resulted in stabilization of the duplex formed with RNA but not with DNA. Similar results were obtained with ASOs bearing phosphorothioate linkages or methoxyethyl (MOE) wings in a gapmer design. All modified ASOs were compatible with E. coli RNase H mediated degradation of target RNA. Substitution of DNA for araUP and araCP in the central portion of a gapmer with MOE wings demonstrated improved nuclease resistance. These results suggest C5‐modified arabinonucleic acids may serve as a potential chemical modification for therapeutic ASOs.
Boosting Direct Oxidation of Methane with Molecular Oxygen at Low Temperature over Rh/ZSM‐5 Catalyst
Authors: Yu Xing , Mao Jianing , Wu Bo , Wei Yao , Sun Yuhan , Zhong Liangshu 
Published: March 2023

AbstractAs a clean fossil energy and chemical feedstock, development of breakthrough strategies for direct conversion of methane (CH4) into various chemicals under mild reaction conditions is highly desired. Herein, Rh/ZSM‐5 catalyst was reported to convert CH4 to oxygenates with molecular oxygen (O2) in the presence of CO at low temperature with promising catalytic performance. The oxygenates productivity reached as high as 5638.0 μmol gcat.−1 h−1. Structure characterization confirmed the existence of highly dispersed Rh2O3 nanoparticles with an average diameter of 2.4 nm in the Rh/ZSM‐5 catalyst. Based on control experiments and mechanism study, it was suggested that CO plays a pivotal role over the Rh/ZSM‐5 catalyst to boost direct oxidation of methane. CO participates in water‐gas‐shift reaction to produce in‐situ H species, which enables to form *OH, *OOH and H2O2 active species by reacting with O2. The as‐obtained *OH, *OOH and H2O2 species will thus render high activity for methane oxidation.
Highly Stereospecific On‐Surface Dimerization into Bishelicenes: Topochemical Ullmann Coupling of Bromohelicene on Au(111)
Authors: Voigt Jan , Martin Kévin , Neziri Egzona , Baljozović Miloš , Wäckerlin Christian , Avarvari Narcis , Ernst Karl‐Heinz 
Published: March 2023

AbstractThe on‐surface dimerization into bis(hexahelicene) on a gold(111) surface has been studied by means of scanning tunneling microscopy and time‐of‐flight secondary mass spectrometry. C−C Ullmann coupling of (rac)‐2‐bromo‐hexahelicene leads to formation of the (M,M)‐ and (P,P)‐diastereomers of 2,2’‐bis(hexahelicene), whilst formation of the (M,P)‐diastereomer is not observed. Upon cooling, the bis(hexahelicene) aggregates into an ordered two‐dimensional lattice with partly randomly distributed enantiomers. The highly specific diastereomeric coupling is explained by the surface alignment of educt in combination with the strong steric overcrowding in a possible surface‐confined (M,P)‐product.
SSAE‐KPLS: A quality‐related process monitoring via integrating stacked sparse autoencoder with kernel partial least squares
Authors: Ye Zhenyu , Wu Ping , He Yuchen , Pan Haipeng 
Published: March 2023

AbstractKernel partial least squares (KPLS) is widely employed to address the issue of nonlinearity inherent in complex industrial processes. However, KPLS can only extract shallow features from process measurements. This paper proposes a new quality‐related process monitoring method via integrating stacked sparse autoencoder (SSAE) with KPLS (SSAE‐KPLS). First, an SSAE model is employed to exploit the nonlinearity within process variables. Through SSAE, hierarchical features are learned to extract latent representations of process variables from multiple sparse autoencoder (SAE) layers. Second, the learned hierarchical features from SSAE are used as input, and the final quality variables are used as output. A KPLS model is then built to exploit the nonlinear relationship between the hierarchical features extracted from process variables and the final product quality for process monitoring. Third, Hotelling's and statistics are employed to detect the quality‐unrelated and quality‐related faults, respectively. Finally, experiments on a numerical example and the commonly used industrial benchmark of the Tennessee Eastman process (TEP) are conducted to illustrate the efficacy and merits of the proposed SSAE‐KPLS based quality‐related process monitoring method by comparing it with other related methods.
Multilayer privacy‐preserving model for security and privacy access control in edge computing
Authors: Karthikeyan K. , Madhavan P. 
Published: March 2023

SummaryIn a recent scenario of a computing environment, the Internet of Things (IoT) provides a greater impact in several applications and services. For that Edge Computing techniques are effectively incorporated, in which the sensitive data are stored on servers. As a result, edge computing allows for data storage and operation at the network's edge to emerge as optimistic advancement. Regardless, the distinctive characteristics of edge computing including real‐time computing, content perception and parallel processing have introduced a number of innovative challenges in the domain of privacy preservation and data security. Edge computing provides an extension of the cloud for designing and deploying new security resolutions in the area of IoT. In this paper, a Trusted Platform Module with Ciphertext‐policy attribute‐based encryption technique is introduced to provide a solution to a multilayer privacy‐preserving model for efficient data storage. The developed model is adaptable and has a reliable data access control mechanism. Further, the results of the experiments demonstrate that the suggested technique operates better and give 83% results in terms of storage cost, load testing, effective runtime execution, higher security, credibility, and efficiency.
Single‐cell transcriptomic analysis deciphers key transitional signatures associated with oncogenic evolution in human intramucosal oesophageal squamous cell carcinoma
Authors: Liu Xin‐Yang , Liu Yan‐Bo , Xu Jia‐Cheng , Zhang Yi‐Fei , Ruan Yuan‐Yuan , Zhao Yi , Wu Lin‐Feng , Hu Jian‐Wei , Zhang Zhen , He Meng‐Jiang , Chen Tian‐Yin , Xu Xiao‐Yue , Zhang Jing‐Wei , Zhang Yi‐Qun , Zhou Ping‐Hong 
Published: March 2023

AbstractBackground and aimsThe early diagnosis and intervention of oesophageal squamous cell carcinoma (ESCC) are particularly important because of the lack of effective therapies and poor prognosis. Comprehensive research on early ESCC at the single‐cell level is rare due to the need for fresh and high‐quality specimens obtained from ESD. This study aims to systematically describe the cellular atlas of human intramucosal ESCC.MethodsFive paired samples of intramucosal ESCC, para‐ESCC oesophageal tissues from endoscopically resected specimens and peripheral blood mononuclear cells were adopted for scRNA‐seq analysis. Computational pipeline scMetabolism was applied to quantify the metabolic diversity of single cells.ResultsA total of 164 715 cells were profiled. Epithelial cells exhibited high intra‐tumoural heterogeneity and two evolutionary trajectories during ESCC tumorigenesis initiated from proliferative cells, and then through an intermediate state, to two different terminal states of normally differentiated epithelial cells or malignant cells, respectively. The abundance of CD8+ TEXs, Tregs and PD1+CD4+T cells suggested an exhausted and suppressive immune microenvironment. Several genes in immune cells, such as CXCL13, CXCR5 and PADI4, were identified as new biomarkers for poor prognosis. A new subcluster of malignant cells associated with metastasis and angiogenesis that appeared at an early stage compared with progressive ESCC was also identified in this study. Intercellular interaction analysis based on ligand–receptor pairs revealed the subcluster of malignant cells interacting with CAFs via the MDK–NCL pathway, which was verified by cell proliferation assay and IHC. This indicates that the interaction may be an important hallmark in the early change of tumour microenvironment and serves as a sign of CAF activation to stimulate downstream pathways for facilitating tumour invasion.ConclusionThis study demonstrates the changes of cell subsets and transcriptional levels in human intramucosal ESCC, which may provide unique insights into the development of novel biomarkers and potential intervention strategies.
Composition and Physical Stability of the Colloidal Dispersion in Veiled Virgin Olive Oil
Authors: Breschi Carlotta , Ferraro Giovanni , Guerrini Lorenzo , Fratini Emiliano , Calamai Luca , Parenti Alessandro , Lunetti Lorenzo , Zanoni Bruno 
Published: March 2023

AbstractVeiled virgin olive oil (VOO) samples of nine different olive cultivars are chosen to have a wide range of physicochemical and biological properties of colloidal dispersions. The contents of proteins and phospholipids range from 40 to 190 mg kg−1 and from 70 to 200 mg kg−1, respectively. The effect of lab‐scale centrifugation on cloudy appearance is studied measuring the decrease of turbidity grade values. The time to obtain unveiled oils (20 NTU) is modeled by a logistic equation, and a clear relationship between the initial water content and the above time is observed with a different trend between two groups of the VOO samples. Four VOO samples are selected to study the aggregation phenomena of microdroplets of water, pulp particles, and olive stone fragments via optical microscopy and dynamic light scattering during lab‐scale gravity sedimentation. All VOOs are unstable with the cloudiness disappearing within the 230 days of investigation due to an overall diameter increase of cloudy components which is modeled by a power‐law equation. The VOO samples, characterized by both small diameter values of dispersed components (150–250 nm) and high values of water content, show the fastest aggregation kinetics, but they have the longest time of cloudiness stability.Practical Applications: Water content and size distribution of VOO cloudy components can be key factors to control the colloidal stability. If removal of cloudy appearance is required, centrifugation can be applied to obtain a fast oil clarification which shows a power law relationship of water content with time. Instead, if physical stability of the colloidal dispersion is required, the aggregation phenomena should be slow down through VOO processing to obtain small diameters of the cloudy components. Tuning both the water content and dispersed phase diameter in the VOO can be the first step towards the control of phenomena related to the colloidal dispersion for every olive oil processing organization, above and beyond the simple removal of cloudy appearance by filtration.