bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reg family proteins contribute to inflammation and pancreatic stellate cells activation in chronic pancreatitis
Authors: Chen Wenting , Imasaka Mai , Lee Miyu , Fukui Hirokazu , Nishiura Hiroshi , Ohmuraya Masaki 
Published: July 2023

AbstractChronic pancreatitis (CP) is a disease characterized by the inflammation and destruction of pancreatic tissue, leading to the replacement of functional tissue with fibrotic tissue. The regenerating gene (Reg) family proteins have recently been implicated in the repair and regeneration of inflamed pancreatic tissue, though the exact mechanisms of their involvement in the pathogenesis of CP are not yet fully understood. To investigate the role of Reg family proteins in CP, we generated global knockout mice (Reg−/−) for Reg1-3 (Reg1,2,3a,3b,3d,3g) genes using the CRISPR/Cas9 system. We then investigated the effect of Reg family protein deficiency in a genetic model of CP (X-SPINK1) mice by knocking out Reg1-3 genes. We examined pancreatic morphology, inflammatory cytokines expression, and activation of pancreatic stellate cells (PSCs) at different ages. Reg−/− mice showed no abnormalities in general growth and pancreas development. Deficiency of Reg1-3 in CP mice led to a reduction in pancreatic parenchymal loss, decreased deposition of collagen, and reduced expression of proinflammatory cytokines. Additionally, Reg proteins were found to stimulate PSCs activation. Overall, our study suggests that Reg1-3 deficiency can lead to the remission of CP and Reg family proteins could be a potential therapeutic target for the treatment of CP.
High sensitivity of asymmetric 18F-THK5351 PET abnormality in patients with corticobasal syndrome
Authors: Kurihara Masanori , Ishibashi Kenji , Matsubara Tomoyasu , Hatano Keiko , Ihara Ryoko , Higashihara Mana , Kameyama Masashi , Tokumaru Aya Midori , Takeda Katsuhiko , Nishina Yasushi , Kanemaru Kazutomi , Ishii Kenji , Iwata Atsushi 
Published: July 2023

AbstractCorticobasal syndrome (CBS) is characterized by symptoms related to the asymmetric involvement of the cerebral cortex and basal ganglia. However, early detection of asymmetric imaging abnormalities can be challenging. Previous studies reported asymmetric 18F-THK5351 PET abnormalities in CBS patients, but the sensitivity for detecting such abnormalities in larger patient samples, including early-stage cases, remains unclear. Patients clinically diagnosed with CBS were recruited. All patients displayed asymmetric symptoms in the cerebral cortex and basal ganglia. Asymmetric THK5351 PET abnormalities were determined through visual assessment. Brain MRI, perfusion SPECT, and dopamine transporter (DAT) SPECT results were retrospectively reviewed. The 15 patients had a median age of 72 years (59–86 years) and a disease duration of 2 years (0.5–7 years). Four patients met the probable and 11 met the possible CBS criteria according to Armstrong criteria at the time of PET examination. All patients, including early-stage cases, exhibited asymmetric tracer uptake contralateral to their symptom-dominant side in the cerebral cortex/subcortical white matter and striatum (100%). The sensitivity for detecting asymmetric imaging abnormalities contralateral to the symptom-dominant side was 86.7% for brain MRI, 81.8% for perfusion SPECT, and 90% for DAT SPECT. White matter volume reduction was observed in the subcortical region of the precentral gyrus with increased THK5351 uptake, occurring significantly more frequently than gray matter volume reduction. THK5351 PET may be a sensitive imaging technique for detecting asymmetric CBS pathologies, including those in early stages.
Revisiting the magnetic structure of Holmium at high pressure by using neutron diffraction
Authors: Pardo-Sainz M. , Cova F. , Rodríguez-Velamazán J. A. , Puente-Orench I. , Kousaka Y. , Mito M. , Campo J. 
Published: July 2023

AbstractLow-temperature neutron diffraction experiments at$$P= 8$$P=8GPa have been conducted to investigate the magnetic structures of metallic Holmium at high pressures by employing a longd-spacing high-flux diffractometer and a Paris-Edinburgh press cell inside a cryostat. We find that at$$P=8$$P=8 GPa and$$T=5$$T=5 K, no nuclear symmetry change is observed, keeping therefore the hexagonal closed packed (hcp) symmetry at high pressure. Our neutron diffraction data confirm that the ferromagnetic state does not exist. The magnetic structure corresponding to the helimagnetic order, which survives down to 5 K, is fully described by the magnetic superspace group formalism. These results are consistent with those previously published using magnetization experiments.
Draft genome sequence and probiotic functional property analysis of Lactobacillus gasseri LM1065 for food industry applications
Authors: Bae Won-Young , Lee Young Jin , Jung Woo-Hyun , Shin So Lim , Kim Tae-Rahk , Sohn Minn 
Published: July 2023

AbstractProbiotics are defined as live organisms in the host that contribute to health benefits. Lactobacillus gasseri LM1065, isolated from human breast milk, was investigated for its probiotic properties based on its genome. Draft genome map and de novo assembly were performed using the PacBio RS II system and hierarchical genome assembly process (HGAP). Probiotic properties were determined by the resistance to gastric conditions, adherence ability, enzyme production, safety assessment and mobile genetic elements. The fungistatic effect and inhibition of hyphae transition were studied using the cell-free supernatant (CFS). L. gasseri LM1065 showed high gastric pepsin tolerance and mild tolerance to bile salts. Auto-aggregation and hydrophobicity were measured to be 61.21% and 61.55%, respectively. The adherence to the human intestinal epithelial cells was measured to be 2.02%. Antibiotic-resistance genes and putative virulence genes were not predicted in the genomic analysis, and antibiotic susceptibility was satisfied by the criteria of the European Food Safety Authority. CFS showed a fungistatic effect and suppressed the tricarboxylic acid cycle in Candida albicans (29.02%). CFS also inhibited the transition to true hyphae and damaged the blastoconidia. This study demonstrates the essential properties of this novel probiotic, L. gasseri LM1065, and potential to inhibit vaginal C. albicans infection.
Facile synthesis of robust Ag/ZnO composites by sol–gel autocombustion and ion-impregnation for the photocatalytic degradation of sucrose
Authors: Buengkitcharoen Lalita , Amnuaypanich Sittipong , Naknonhan Suriyabhorn , Loiha Sirinuch , Patdhanagul Nopbhasinthu , Makdee Ammarika , Amnuaypanich Sujitra 
Published: July 2023

AbstractMetallic Ag nanoparticles decorated on ZnO photocatalysts were prepared by facile sol–gel autocombustion followed by ion-impregnation. Electron microscopy studies revealed the presence of impregnated Ag as nanoparticles on ZnO surfaces, which affected the microstructure of ZnO particles. XRD patterns of Ag/ZnO composites confirmed the metallic phase of Ag. No peak shift for ZnO phase peaks suggests that the impregnated Ag was barely incorporated into the ZnO lattice. Consequently, DRS spectra of Ag/ZnO composites revealed the same absorption edges and Eg for pure and Ag/ZnO. The photocatalytic activity of Ag/ZnO composites for sucrose degradation under UV light was 40% higher than that of pure ZnO. Metallic Ag nanoparticles on the ZnO surface suppressed the surface defects and the recombination of photoexcited electrons and holes. The highest activity with 100% degradation of 100 ppm sucrose (1200 µg of carbon) within 105 min was achieved using ZnO with 10% w/w Ag (10% Ag/ZnO). Ag L3-edge XANES spectra of fresh and spent Ag/ZnO catalysts confirmed the stability of metallic Ag after the usage. The Ag/ZnO catalyst could be used for 5 cycles without losing photocatalytic activity. The Ag/ZnO catalyst was utilized to degrade sugar-contaminated condensate from the sugar mill. 10% Ag/ZnO revealed the highest photocatalytic performance, capable of degrading 90% of sugar in the condensate within 90 min.
Umsetzung von Rehanachsorgeangeboten bei Kindern und Jugendlichen.
Perspektiven aus der Praxis
Authors: Stumm Judith , Fahrenkrog Sandra , Klüpfel Laura , Spyra Karla 
Published: July 2023

Zusammenfassung
Hintergrund und Zielstellung Für einen langfristigen und
nachhaltigen Rehaerfolg bei chronisch erkrankten Kindern und Jugendlichen wurde
mit Inkrafttreten des Flexirentengesetzes unter anderem die Durchführung
der Rehanachsorge für Kinder und Jugendliche ermöglicht.
Für die Umsetzung und Nutzung von Rehanachsorgeprogrammen gilt es,
verschiedene Barrieren und Herausforderungen zu überwinden und
involvierte Akteur*innen rollenspezifisch mit einzubeziehen. Ziel der
qualitativen Studie war es, die Perspektiven von
Kinderärzt*innen und Rehaklinikmitarbeiter*innen
hinsichtlich des Wissensstandes, des Bedarfs sowie der Barrieren in Bezug auf
Nachsorgeangebote für Kinder und Jugendliche zu untersuchen.
Methodik Es wurden 20 semistrukturierte Telefoninterviews mit
niedergelassenen Kinder- und Jugendärzt*innen (N=10)
sowie Rehaklinikmitarbeiter*innen (N=10) geführt. Die
Daten wurden audiodigital aufgenommen, anonymisiert transkribiert und
inhaltsanalytisch ausgewertet.
Ergebnisse Sowohl die niedergelassenen Ärzt*innen als auch
die Klinikmitarbeiter*innen sind positiv gegenüber dem Konzept
der Rehanachsorge eingestellt. Mangelnde Informationen, fehlende
Kommunikationswege, knappe zeitliche Ressourcen und unklare
Verantwortungsbereiche sind Gründe für die
zurückhaltende Nutzung von Rehanachsorgeangeboten.
Schlussfolgerung Rehanachsorgeangebote für Kinder und Jugendliche
stellen eine essentielle Ergänzung zur medizinischen Rehabilitation dar.
Barrieren und Herausforderungen im Zugang und der Nutzung sollten
zunächst aus der Perspektive von Versorger*innen beleuchtet und
berücksichtigt werden. Eine gezielte Informationspolitik zu bestehenden
Nachsorgeangeboten sowie eine standardisierte Regelung der
Zuständigkeiten können eine Umsetzung und Nutzung von
Rehanachsorgeangeboten fördern und die jeweiligen Akteur*innen
entlasten.
Indirect translation and its influence on term variation
Authors: Cabezas-García Melania , León-Araúz Pilar 
Published: July 2023

Abstract
Term variation occurs when different designations are used to name the same concept. In institutional settings,
such as the European Union, term variants multiply, partly as a result of the different languages and directions involved.
Indirect translation is a recurrent practice in these multilingual contexts since it limits the number of language combinations,
besides reducing costs and the need for translators. This paper describes how indirect translation via English has an influence on
Spanish term variation in the European Union. We analyzed the EUR-Lex and Europarl English and Spanish corpora in Sketch Engine.
The focus was on concepts related to Sustainable Development Goal 13: Climate Action, which are specifically
addressed in these institutional corpora as a result of a long-standing environmental awareness. Our analysis indicates that
indirect translation seems to have a subtle effect on term variants, since their proliferation seems to be mitigated when indirect
translation is used.
Greybody factors for higher-dimensional non-commutative geometry inspired black holes
Authors: Cox Zachary , Gingrich Douglas M 
Published: July 2023

Abstract
Greybody factors are computed for massless fields of spin 0, 1/2, 1, and 2 emitted from higher-dimensional non-commutative geometry inspired black holes. Short-range potentials are used with path-ordered matrix exponentials to numerically calculate transmission coefficients. The resulting absorption cross sections and emission spectra are computed on the brane and compared with the higher-dimensional Schwarzschild–Tangherlini black hole. A non-commutative black hole at its maximum temperature in seven extra dimensions will radiate a particle flux and power of 0.72–0.81 and 0.75–0.81, respectively, times lower than a Schwarzschild–Tangherlini black hole of the same temperature. A non-commutative black hole at its maximum temperature in seven extra dimensions will radiate a particle flux and power of 0.64–0.72 and 0.60–0.64, respectively, times lower than a Schwarzschild–Tangherlini black hole of the same mass.
Spin wave based weak magnetic field measurement at room temperature using magnonic crystal
Authors: Chauhan Kinjal A , Sharma Anuj K , Prajapati Yogendra Kumar 
Published: July 2023

Abstract
We describe a weak magnetic field sensor operating at room temperature based on the magnonic crystal (MC). MC consisting of periodic stripes of cobalt (Co) and permalloy (Py) in one dimension is studied. The magnonic bandgaps are calculated by solving the eigenvalue problem of the Landau–Lifshitz equation using the finite element method. Magnonic bandgap frequency shifts depend upon the external magnetic field and this phenomenon is utilized for magnetic field sensing. The sensitivity characteristics of MCs with dispersion spectra in the gigahertz (GHz) frequency range are studied. It is found that the sensor’s performance gets enhanced for smaller thickness and larger periodicity. The sensitivity reaches a magnitude as large as 66.0 GHz T−1 for 10 nm thickness and 1 μm periodicity. Our analysis indicates that a limit of detection (LOD) of the order of 10−11 T can be achieved for all the geometric configurations considered in the 0–1 T range. The results are explained in terms of corresponding fundamental concepts and phenomena. Further, our simulation results show that the typical gap (e.g. 1 nm) between Co and Py stripes does not significantly affect the sensitivity of the sensor. The results also indicate that any small variation (e.g. 1 nm) in MC thickness may lead to reasonable variation in sensitivity magnitudes. Moreover, the proposed sensor’s performance is significantly superior (in terms of sensitivity, LOD, miniaturization, and material, etc) to the currently available state-of-the-art magnetometers.
A recognition method of less databases by using decoupling parallel CNN based on multiple feature with DAS
Authors: Huang Sheng , Chai Quan , Jia Muxin , Tian Ye , Lewis Elfed , Zhang Jianzhong 
Published: July 2023

Abstract
The integration of artificial intelligence and distributed fiber optic acoustic sensing technology (DAS) has yielded remarkable results in recent years; however, some application scenarios face the challenge of acquiring an adequate amount of data for higher network accuracy. To address this issue, we propose a decoupling parallel convolutional neural network (DPCNN) that relies on multiple feature inputs to achieve higher accuracy while using smaller databases. Our model offers excellent recognition of five events, including background noise, footstep, digging, car passing, and climbing fence, with an accuracy rate of up to 94.9%. The DPCNN is a parallel and lightweight convolutional neural network (CNN) that boasts a short training time of only 3.76 s per epoch and a test time of 0.1175 s, with superior network convergence. In comparison to a mature single-branch CNN based on mixed images of time-frequency and time-space, the DPCNN accuracy is 6.4% higher. Our model demonstrates excellent performance across various databases and can achieve recognition accuracy of up to 98.7% with larger databases. Finally, we show the broad range of applications available for DPCNN based on multiple feature inputs when using a mature single-branch replacement in each branch of a two-branch network.
Empirical Ramanujan decomposition and iterative envelope spectrum for fault diagnosis
Authors: Cheng Jian , Yang Yu , Hu Niaoqing , Cheng Zhe , Cheng Junsheng 
Published: July 2023

Abstract
Ramanujan Fourier mode decomposition obtains components by scanning from low frequency to high frequency, which will cause too many components, and then the fault information in mode components is incomplete. Based on this, the empirical Ramanujan decomposition (ERD) method is proposed. Firstly, ERD uses the optimized lowest minima technique to segment the spectrum and determines the segmentation boundary and the number of components. Subsequently, ERD constructs the filter bank for filtering and retains the spectral components corresponding to the main frequency band. Finally, the time domain components are recovered by the inverse Ramanujan Fourier transform. To further improve the capability of envelope spectrum (ES), an iterative ES (IES) method is proposed. IES enhances the periodic components through iterative envelope to make the fault feature more conspicuous. The analysis results of simulation and experimental signals show that the ERD and IES can extract features effectively.
Temperature and strain SAW/BAW sensors on metallic substrates with RFID capability
Authors: Mengue Prince , Paulmier Baptiste , Hage-Ali Sami , Noirel Cyril , Poncot Marc , Floer Cécile , M’Jahed Hamid , Shvetsov Alexander , Zhgoon Sergei , Nicolay Pascal , Elmazria Omar 
Published: July 2023

AbstractSurface acoustic wave (SAW) strain sensors require an adhesive—typically a glue—for the mounting on the part under measurement. This comes with strain-transfer, reproducibility and aging issues. In this paper, we propose a novel glue-less solution where the SAW sensor is directly fabricated onto the surface of interest, here a metallic substrate. Here, we study the layered structure ZnO/Ti numerically and experimentally, with ZnO as the piezoelectric layer and titanium as the substrate. In this structure, both bulk acoustic waves and SAW can propagate, and we used both of them to monitor temperature variations up to 300 °C and strain levels up to 1800μϵ. Moreover, reflective delay line (R-DL) designs were used, to provide the future users with radio frequency identification functionalities. In order to overcome the limitations due to the relatively low electromechanical coupling coefficient of ZnO/Ti, a specific R-DL layout with connected inter-digital transducers was used. The obtained experimental results confirm that the proposed glue-less R-DL structure is a promising solution for the independent evaluation of temperature and strain, with identification.
Shape recovery and mechanical properties investigation of carbon fiber dispersed bisphenol-A based epoxy composite
Authors: Yadav Avadesh , Kumar Singh Sourabh , Das Sreetam , Kumar Satish , Kumar Abhishek 
Published: July 2023

Abstract
Shape memory polymers (SMPs) are employed in a wide range of fields because to their appealing properties, which include low density, low production costs, and ease of processing. In the present work, SMP composites were developed using ultrasonic mixing of carbon fiber (CF) and amorphous epoxy to enhance the properties of epoxy and shape memory effect. The prepared composites were tested for mechanical and shape memory properties. Flexural strength and tensile strength of pristine epoxy enhanced after dispersing 1% CF which are about 12.7% and 16.2%, respectively, higher than pristine epoxy. Fracture toughness of epoxy improves after adding 1% CF which is about 94.05% higher compared to pristine epoxy. UV–vis-NIR showed reduction in energy bandgap. Shape fixity and shape recovery ratios for pristine epoxy was 98.49% and 93.40%, respectively. These ratios decrease to 90.52% and 87.86%, respectively with addition of 1.5 wt.% CF. However, recovery time improves from 57 s to 33 s with addition of 1.5 wt.% CF in epoxy. Shape recovery rate enhances with CF reinforcement in epoxy composite.
Final ion yields upon the cascade decay of single K, L, M, and N vacancies in atomic silver
Authors: Chaynikov A P , Kochur A G , Dudenko A I , Yavna V A 
Published: July 2023

Abstract
Final ion yields and mean final ion charges upon the cascade decay of single vacancies in the K, L, M, and N shells of atomic silver are calculated using the method of construction and analysis of the decay trees with accounting for the shake-offs caused by the change of atomic core potential due to cascade transitions. The shake-off effect on the final ion yields is found to be comparatively small, the largest increase of the mean final ion charge being 0.20e in the case of initial 2s vacancy. Total semi-relativistic Pauli–Fock energies of cascade-produced ionic configurations were used to calculate cascade transition energies, which made it possible to accurately account for the closing of some non-radiative transitions in multivacancy cascade configurations. For the transitions with overlapping multiplets of initial and final ionic configurations, only energetically allowed transitions between the multiplet components were counted when calculating mean transition energies and transitions branching ratios. Comparison of calculated charge spectra with those reported earlier by other authors demonstrated crucial importance of accurate calculation of transition energies and accounting for multiplet splitting in simulation of cascades in heavy atoms.
Influence of heat treatment on microstructure and mechanical properties of pulsed Nd: YAG laser welded dissimilar sheets of Hastelloy C-276 and monel 400
Authors: Shanthos Kumar G , Sivamaran V , Lokanadham R , Raju C , Mandal T K 
Published: July 2023

Abstract
The study involved using a pulsed Nd:YAG laser welded Hastelloy C-276-Monel 400 dissimilar sheet by the process parameters viz. a pulse energy of 10 J, pulse repetition rate of 20 Hz and pulse duration of 0.006 s under spot weld mode. The objective was to investigate the effects of various post weld heat treatment (PWHT) conditions on the welded sheets. Microscopic analysis showed that the fusion zone and interfaces between the two metals contained smaller dendritic grains containing chromium-rich carbides and nickel-rich oxides. Both the Hastelloy C-276 and Monel 400 interfaces exhibited these traits. The PWHT of the quenched weld (water cooling) produced higher mechanical strength, while the annealed weld (furnace cooling) resulted in lower strength. Tensile failures were observed in the fusion zone for quenched and normalized welds, and in the base alloy of Hastelloy C-276 side for annealed weld under ductile fracture mode. XRD analysis showed the presence of more secondary phases and intermetallic compounds in the fusion zone and Hastelloy C-276 side in the annealed weld. The corrosion study indicated that the fusion zone and Monel 400 side had better corrosion resistance, followed by the Hastelloy C-276 side.
Collective dynamics of two coupled Hopfield inertial neurons with different activation functions: theoretical study and microcontroller implementation
Authors: Madasamy Ettappan , Boui a Boya Bertrand Frederick , Kengne Jacques , Rajagopal Karthikeyan 
Published: July 2023

Abstract
This work deals with the regular and chaotic dynamics of a system made up of two Hopfield-type neurons with two different activation functions: the hyperbolic tangent function and the Crespi function. The mathematical model is in the form of an autonomous differential system of order four with odd symmetry. The analysis highlights nine equilibrium points and four of these points experience a Hopf bifurcation at the same critical value of a control parameter which can be either the diss1ipation parameter or one of the coupling coefficients. This makes plausible the presence of four parallel bifurcation branches as well as the coexistence of multiple attractors in the behavior of the system. One of the highlights revealed in this work is the coexistence of three double-scroll type attractors of particular topology as well as the presence of a four-spiral attractor. Furthermore, the coexistence of both self-excited and hidden dynamics is also reported. All this plethora of dynamics is elucidated by making use of the usual tools for analyzing nonlinear systems such as bifurcation diagrams, the maximum of Lyapunov exponent, basins of attractions as well as phase portraits. A physical implementation of the microcontroller-based system is envisaged in order to confirm the plethora of behaviors observed theoretically.