bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rol y valor patrimonial del Balloon Frame en la arquitectura industrial en Chile
Authors: Pizzi Marcela 
Published: January 2023

Históricamente, el desarrollo económico ha sido un elemento clave en la configuración de los paisajes y centros urbanos. Ello sucede de modo más relevante con el advenimiento de la Revolución Industrial y los consecuentes procesos de comercialización y colonización en que los países más desarrollados buscaron nuevos territorios y materias primas para su sustento, manifestándose ello con fuerza a partir de mediados del siglo diecinueve.
Asimismo, asociado a este fenómeno, se desarrolla el ingenio innovativo en todos los campos, y en el caso del medio ambiente construido, la generación de nuevos sistemas constructivos a partir de los materiales disponibles y avances tecnológicos, los que
son utilizados para acoger tanto las actividades productivas como para albergar las necesidades de los trabajadores y sus familias. En dicho contexto la madera, en tanto elemento constructivo, adquirió protagonismo a nivel global con la creación de sistemas de entramado liviano que permitieron no solo dar rápida respuesta a dichas necesidades sino también generar un nuevo carácter en el paisaje con valores globales pero también locales, como en el caso de Chile.
El presente artículo explora las condicionantes económicas asociadas a dicho proceso y los precedentes de los sistemas foráneos de entramado liviano en madera, examinando sus expresiones más relevantes en nuestro país y relevando las características de su evolución que dieron origen a paisajes únicos y propios.
Physiological interaction of SARS-CoV-2 binding to the ACE-2 receptor
Authors: Anwar Saadia , Bhatti Iqra Heer , Mughal Amna , Abbasi Samia Shoukat , Mujtaba Mariam Ahmed , Qureshi Muhammad Sheraz , Rizwan Muhammad , Sharma Ravi Dutt 
Published: January 2023

For a better knowledge of how viruses enter cells, the associations that are created between the viral glycoproteins and associated human receptors must be studied. The spike glycoprotein (S-glycoprotein) of the new coronavirus SARS-CoV-2 mediates entrance into host cells, and the cellular receptor angiotensin-converting enzyme 2 (ACE-2) has been discovered.The goal of our research was to evaluate the physiological interactions between the SARSCoV-2 and the human cell receptor ACE-2.Modifications were discovered in the S1 monomer of the receptor-binding domain of spikes using an in silico analysis. The observed modifications have a considerable impact on the interlinkage between the SARS-CoV-2 spike and ACE-2. According to the research outcome, the SARS-Cov-2 spikes proteinhas a strong attraction for the human ACE-2 receptor than the Bat-CoV spikes does. Further, the presence of two loops throughout the SARS-CoV-2 receptor binding domain (RBD) may facilitate binding to the ACE-2 (receptor)throughenhancing the quantity of atoms implicated. The reason SARS-CoV-2 binds to substrates with higher binding energies than SARS-CoV may be due to longer capping loops and changed amino acids.
Second Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients
Authors: Freedman Isaac G. , Dowd Hollie N. , Dhodapkar Meera M. , Halperin Scott J. , Grauer Jonathan N. 
Published: January 2023

Background:
Osteosarcoma is the most common primary bone tumor in children, adolescents, and young adults. Second primary malignancies (SPMs) are a potential serious long-term event that can occur in osteosarcoma survivors.

Methods:
The National Cancer Institute's Surveillance, Epidemiology, and End Results 18 database was queried for all osteosarcoma cases from 2000 through 2015. Standardized incidence ratio (SIR) and absolute excess risk (AER) of SPM per 10,000 persons (AER) relative to representative population-level data were calculated across for various anatomic locations.

Results:
In total, 3438 patients with osteosarcoma were identified. Of these patients, 79 (2.3%) developed SPMs, with an SIR of 2.84 (95% confidence interval [CI] 2.35 to 3.39, P < 0.0001) and an AER of 44.96. The most common SPMs were tumors of the bones or joints (SIR 73.07, CI, 38.90 to 124.94, P < 0.0001, AER 7.48), tumors of soft tissues including the heart (SIR 15.19, CI, 5.58 to 33.07, P < 0.0001, AER 3.27), and leukemia (SIR 22.28, CI, 15.03 to 31.80, P < 0.0001, AER 16.74).

Conclusion:
The overall incidence of SPMs in osteosarcoma survivors was significantly higher than would otherwise be expected for this population. Considering the occurrence and targeting surveillance for SPM in the osteosarcoma patient population is warranted.
EFEITOS DA CEFALEIA DO TIPO TENSIONAL NO RENDIMENTO ACADÊMICO E NAS ATIVIDADES COTIDIANAS DE UNIVERSITÁRIOS DO SERTÃO PERNAMBUCANO
Authors: Sampaio Anna Caroline Loyola , Pereira Dryelle Daianne do Nascimento , Coelho Jéssica dos Santos , Arruda Mariana Vitória Souza , Prado Giovanna Francchine Santos , Conegundes Clinton Henry Colaço , Angelo Rita di Cássia de Oliveira , Ferraz Rosana Paula Cruz 
Published: January 2023

Introdução: Os universitários, em especial dos cursos da saúde, são um dos grupos mais acometidos pela cefaleia do tipo tensional (CTT), tendo em vista a carga exaustiva de atividades a qual estes indivíduos estão expostos, o que pode desencadear intenso estresse emocional, redução da produtividade e da qualidade de vida. Objetivo: Investigar a frequência de CTT em um grupo de estudantes universitários do Sertão do estado de Pernambuco – Brasil, bem como analisar o impacto da referida desordem neurológica sobre o rendimento acadêmico e as atividades cotidianas daqueles com critérios positivos para CTT. Metodologia: Trata-se de um estudo do tipo descritivo, de corte transversal e exploratório, cuja coleta de dados ocorreu mediante a aplicação de questionários para investigação sociodemográfica e acadêmica, para rastreio da CTT, para categorização da intensidade da dor e avaliação dos prejuízos na vida acadêmica e na vida cotidiana. Resultados: A amostra final constituiu-se por 121 participantes, de ambos os sexos, com predomínio de indivíduos do sexo feminino, faixa etária superior a 18 e inferior a 25 anos. Dentre os universitários com rastreio positivo para CTT, observou-se critérios compatíveis com: CTT episódica pouco frequente em 23,6%, com mediana da dor referida de 5; CTT episódica frequente em 16,7%, com mediana da dor de 6; CTT crônica em 4,2%, com mediana da dor de 6; CTT provável em 55,5%, com mediana da dor de 5. Houve relação direta e significativa entre a presença de CTT, a frequência e a duração de episódios, bem como presença de fonofobia ou fotofobia. A análise da relação entre o nível de interferência da CTT nas atividades cotidianas e na vida acadêmica dos universitários, e a intensidade da dor percebida mostrou correlação linear direta e significativa entre todas as variáveis. Conclusão: A CTT, portanto, compromete as atividades acadêmicas e profissionais, bem como a qualidade de vida dos estudantes da área da saúde que possuem esse distúrbio. Ressalta-se, ainda, a necessidade de instrumentos de rastreio validados e eficazes para obter-se dados com maior especificidade a fim de formular melhores estratégias de manejo dessa desordem e evitar a evolução para outros distúrbios neurológicos.
COMBATE AO USO INDISCRIMINADO DE ANTIMICROBIANOS EM PRODUÇÕES AVÍCOLAS NO SEMIÁRIDO PARAIBANO PARA TORNÁ-LAS MAIS SUSTENTÁVEIS E PERFIL DE SUSCEPTIBILIDADE ANTIMICROBIANA DE ENTEROBACTÉRIAS
Authors: Nascimento Carlos Eduardo de Oliveira , de Farias Allamy Jorge Luciano Fernandes , Santos Lincoln Moreira de Aquino Miranda , Melo Junior Francisco Jackson de Oliveira , Silva Afonso Gualberto Dantas , De Oliveira Jefferson wandell Mendes , Da Silva Maria Lindervania Pajeú , De Sousa Débora Luíse Canuto , De Souza Mônica Adriana Araújo , Santos Carolina de Sousa Américo Batista , Brandão Patrícia Araújo 
Published: January 2023

A crescente resistência bacteriana aos antibióticos acendeu um sinal vermelho levando os órgãos reguladores a serem mais rigorosos com relação ao uso de antibióticos na alimentação animal, atentando que resíduos destes medicamentos presentes nas carcaças podem ser transferidos para os humanos por meio da alimentação. O objetivo desta pesquisa foi avaliar as técnicas de manejo e os parâmetros produtivos das aves criadas em diferentes sistemas de produção na região do semiárido paraibano. Foram selecionados aleatoriamente 40 frangos sem alterações neurológicas, de ambos os sexos e com idade a partir de 25 dias, de criações tecnificadas no semiárido paraibano e realizadas coletas com swab estéril direto da cloaca dos animais. Feita a identificação das enterobactérias presentes nas fezes dos animais e realizada a qualificação da variedade de espécies desses microrganismos que compõem a microbiota fecal dos indivíduos estudados. Posteriormente, foi realizado antibiograma e teste fenotípico para ESBL (Beta-lactamase de espectro estendido). Os dados foram computados e tabulados para possível organização, leitura e interpretação dos dados, assim como realizada estatística descritiva, calculando-se as frequências absoluta e relativa. Na granja de poedeiras, foi utilizada ração com adição de premix, a qual não possui antibióticos em sua composição. Enquanto que na granja de frangos de corte, observou-se antibióticos na composição da ração e também em uso terapêutico no tratamento de determinadas enfermidades. Foram identificadas bactérias multirresistentes em ambos os sistemas de produção, sendo verificados 94% dos isolados na granja de galinhas poedeiras e 100% na granja de frango de corte, respectivamente.
Binary Training Sessions: Meaningful Content and Educational Effects
Authors: Nadtochiy Yulia 
Published: January 2023

The advantages of binary classes in domestic and foreign pedagogy have been discussed for quite a long time. However, in most cases, various binary activities (lessons) at school are described. The study is based on the practical experience of using binary classes in an educational organization of higher education (on the example of such disciplines as &quot;management&quot; and &quot;logic&quot;). The article presents the development of a specific task, taking into account the relationship of such scientific fields as logic and management, and also an attempt is made to consider further possibilities for the active use of various interdisciplinary connections (interdisciplinary integration) for organizing and conducting various binary / integrated classes in order to stimulate and develop cognitive interest, increasing attention to the material studied by students, to the further study of various training courses, etc. The importance of binary classes for the intellectual development of students and the development of such practical skills as applying, transferring to new areas and supplement/expand existing knowledge is also substantiated.
ANALISIS KALIUM IODAT (KIO3) DALAM GARAM DAPUR PRODUKSI KUALA BAU ACEH SELATAN
Authors: Adriani Azmalina , Fauziah  , Ria Ranti Sri 
Published: January 2023

Dalam garam dapur harus terdapat Kalium Iodat (KIO3) yang merupakan iodium dalam garam yang sangat penting untuk sintesa hormon tiroid. Garam biasa digunakan sebagai bahan tambahan pangan yang mengandung mineral untuk memenuhi kebutuhan gizi. Tujuan penelitian ini adalah untuk mengetahui ada atau tidaknya kalium iodat dalam garam dapur serta menentukan kadar KIO3 dalam garam dapur produksi Kuala Bau Aceh Selatan. Penelitian ini dilakukan di laboratorium Analis Farmasi dan Makanan Banda Aceh. Metode penelitian dilakukan secara uji kualitatif dengan reaksi warna dan uji kuantitatif pada 4 sampel dengan metode Iodometri. Pengambilan sampel secara total sampling. Hasil penelitian menunjukkan bahwa keempat sampel garam yang di analisa positif mengandung KIO3 dengan kadar rata-rata kalium iodat KIO3 dalam sampel garam A yaitu 37,65 ppm, garam B 35.37 ppm, garam C 35.23 ppm dan garam D 36.56. Dari hasil analisis keempat garam tersebut memenuhi syarat yang telah ditentukan oleh SNI 01-3556-2016 yaitu 30-80 ppm.
Kata kunci : Garam, Iodometri, Kalium Iodat (KIO3)
Pembelajaran Menulis Cerita Pendek Menggunakan Aplikasi Wattpad
Authors: Ningrum Dwi Maula Fitri , Ristiyani Ristiyani , Roysa Mila 
Published: January 2023

Tujuan penelitian ini adalah untuk mengetahui aktivitas siswa dalam menulis cerita pendek menggunakan aplikasi Wattpad di SMA 1 Mejobo. Perkembangan teknologi informasi dan komunikasi yang semakin pesat terutama di bidang pendidikan memiliki peranan penting dalam menarik minat belajar siswa khususnya pembelajaran menulis cerita pendek. Peneliti menggunakan media Wattpad pada saat pembelajaran menulis cerita pendek untuk merangsang kreatifitas, minat menulis siswa dan untuk melihat kemampuan menulis teks cerita pendek. Jenis penelitian ini menggunakan penelitian kualitatif dengan metode deskriptif. Subjek penelitiannya adalah siswa kelas XI MIPA1 SMA N 1 Mejobo dan objeknya adalah cerita pendek yang ditulis siswa dengan menggunakan aplikasi Wattpad. Teknik pengumpulan data yaitu observasi, dokumentasi, dan wawancara. Sampel penelitian yang diambil yaitu siswa kelas XI MIPA 1 di SMA N 1 Mejobo.
Manifiesto Eikasía
Authors: Eikasía Grupo , Hidalgo Tuñón Alberto , Pérez Herranz Fernando Miguel , Sánchez Corredera Silverio , Sánchez Ortiz de Urbina Ricardo , García-Rovés Marcos , García Fernández Román 
Published: January 2023

Conviene subrayar en la época de la ciencia, cuando las prácticas más aberrantes y las especulaciones más desaforadas compiten por arrogarse el título de ciencias, que la filosofía no es una ciencia, ni necesita serlo para ejercer sus funciones críticas. No obstante, mantiene una relación íntima y constante con las ciencias desde sus orígenes hasta nuestros días (relación histórica), utiliza el mismo instrumento metodológico, la razón crítica (relación metódica) y recorre el mismo ámbito de la experiencia cognoscitiva humana (relación sistemática).
En ese sentido, la filosofía no se arredra ante el discurso postmoderno de la deslegitimación —Lyotard, Baudrillard, Vattimo, etc.—. Aunque las soluciones filosóficas son legitimadoras, no se reducen a mera ideología, ni tecnocrática ni progresista.
Assessment of Physicians’ Awareness of Radiation Exposure and Patient Radiation Protection in Mogadishu, Somalia
Authors: Osman Ahmed Adam , Kusbeci Mahmut , Ibrahim Ismail Gedi , Buber Ahmed , Eraslan Asir , Hussein Ahmed Abdirahman , Mohamed Nur Adam 
Published: January 2023

Abstract
Objective: Diagnostic investigations using radiation have become a critical feature of medical practice in recent times, and the possibility of doctors’ underestimation of over-exposure risks to patients from diagnostic radiation is a matter of concern. Therefore, the purpose of this study was to evaluate medical doctors’ awareness of radiation exposure in selected diagnostic radiology centers in Mogadishu.
Methods: This was a descriptive cross-sectional study of the awareness of doctors about radiation exposure in diagnostic radiology investigations in Somalia. Online questionnaires were distributed to 200 medical doctors working in 3 state and 7 private hospitals in Mogadishu. The study was conducted online during the COVID-19 pandemic. Our data analysis was descriptive with a quantitative method, with univariate level analysis only for all variables.
Results: Of the 200 participants, 62% had no formal training on radiation exposure. 86% of our respondents had no idea of the quantity of radiation. Whereas only 10.5% of our respondents correctly estimated the quantity of radiation.
Conclusion: As a result of the high rate of poor awareness of radiation risks observed in the study, it is important that the Somali Ministry of Health and state-level health ministries must guarantee and implement appropriate radiological examination guidelines and national radiation policies and apply it to all levels of healthcare services.
PENGARUH MOTIVASI KERJA TERHADAP KINERJA KARYAWAN BANK MAYBANK CIREBON
Authors: Mariana Putri  , Arin  , Andika Saputra  
Published: January 2023

Work motivation has a crucial role in increasing work performance in employees because with motivation, each employee has the will to work hard and fulfill the company’s target. PT Bank Maybank Cirebon is a private banking company which demands its human resource to keep improving in order to increase their performance so that the quality and performance of the company can also increase. This research’s purpose was to analyze the effect of work motivation toward employee’s performance in PT Bank Maybank Cirebon branch. Research method used in this study was a quantitative method with questionnaire data gathering technique. Research samples were determined using saturated sampling method with a total of 56 respondents. Data analysis methods used in this study include validity test, reliability test, simple regression analysis, t-test, and determination coefficient analysis with the help of Minitab program version 17.3.1. From the research results, it was obtained that work motivation had a positive effect toward employee’s work performance in PT Bank Maybank Cirebon with correlation percentage of 19.74%.
Abstrak
Motivasi kerja memiliki peranan penting dalam meningkatkan kinerja karyawan karena dengan motivasi diharapkan setiap karyawan memiliki kemauan untuk bekerja keras dan dapat memenuhi target yang telah ditetapkan oleh perusahaan. PT Bank Maybank Cirebon merupakan perusahaan perbankan swasta yang menuntut peranan sumber daya manusianya untuk terus berkembang dalam meningkatkan kinerja karyawannya sehingga kualitas dan kinerja perusahaan juga dapat meningkat. Penelitian ini bertujuan untuk menganalisis pengaruh motivasi kerja terhadap kinerja karyawan pada PT Bank Maybank Cabang Cirebon. Metode penelitian yang digunakan adalah metode penelitian kuantitatif dengan teknik pengumpulan data menggunakan kuesioner. Sampel penelitian ditentukan dengan metode sampling jenuh dengan jumlah total sebanyak 56 responden. Metode analisis data dalam penelitian ini meliputi uji validitas, uji reliabilitas, analisis regresi linier sederhana, uji t, dan analisis koefisien determinasi dengan bantuan program Minitab versi 17.3.1. Dari hasil penelitian yang dilakukan, diperoleh kesimpulan bahwa motivasi kerja berpengaruh positif terhadap kinerja karyawan di PT Bank Maybank Cirebon dengan persentase korelasi sebesar 19,74%.
ANALISIS LAPORAN KEUANGAN UNTUK MENGUKUR KINERJA KEUANGAN PADA PT VINCENT SHEPPARD INDONESIA PERIODE 2017-2021
Authors: Lydia Monica  , Suripto  , Yenni Rohmatun  
Published: January 2023

This study aims to detemine the financial performance of companies that are assessed by financial ratio analysis in the company PT Vincent Sheppard Indonesia on period 2017, 2018, 2019, 2020 and 2021. The data analysis method used in this study is a quantitative method by measuring the liquidity ratio namely the current ratio and quick ratio, the activity ratio namely the total aset turnover ratio, fixed asset turnover ratio and receivbles turnover ratio, ratio profitability which includes the rasio of gross profit margin, net profit margin and ROE. Based on the results of research on the liquidity ratio of the period 2017 to 2021 is categorized as healthy because the company can inhabit liabilities, then based on the company’s activity ratio in the period 2017 to 2021 categorized as very healthy due to asset and receivable turnover very controlled, and the last one is based pn the company’s profitability ratio categorized as healthy because profit always increase from year to year.
ABSTRAK
Penelitian ini bertujuan untuk mengetahui kinerja keuangan perusahaan yang dinilai dari analisis rasio keuangan pada PT Vincent Sheppard Indonesia pada periode 2017, 2018, 2019, 2020 dan 2021. Metode analisis data yang digunakan dalam penelitian ini adalah metode kuantitatif dengan pengukuran rasio likuiditas yaitu rasio lancar dan rasio cepat, rasio aktivitas yaitu rasio perputaran total aset, rasio perputaran aset tetap dan rasio perputaran piutang, lalu rasio profitabilitas yang mencakup rasio margin laba kotor, margin laba bersih dan ROE. Berdasarkan hasil penelitian rasio likuiditas periode 2017 sampai 2021 dikategorikan sehat karena perusahaan dapat melunasi kewajibannya, selanjutnya berdasarkan rasio aktivitas perusahaan pada periode 2017 sampai 2021 dikategorikan sangat sehat karena perputaran aset dan piutang sangat terkendali, dan yang terakhir berdasarkan rasio profitabilitas perusahaan dikategorikan sehat karena laba selalu mengalami peningkatan dari tahun ke tahun.
DAMPAK PENGETAHUAN PRODUK DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN LABU MADU DI PT ASKARA FARM INDONESIA
Authors: Alvi Velayati  , Vina Andita Pratiwi  , Asep Kosasih  
Published: January 2023

This study aims to analyze the impact of product knowledge and promotion on honey pumpkin buying decisions at PT Askara Farm Indonesia. The research method uses a quantitative descriptive method with a survey approach with a sample 75 people. Data was collected by filling out a questionnaire for product knowledge and promotion with buying decisions. Then the data colleted was analyzed using SPSS 16.0 for windows a significance level (α) of 0,05 with data analysis methods consisting of Validity Test, Reliability Test, Classical Asumption Test ( Normality Test, Heteroscedastisity Test, Multicolinearity Test), Multiple Linear Regression Analysis, Coefficient of Determination and Hypothesis Testing. From the results of the study, the tcount value of the product knowledge variable (X1) was 2,509 ttable, namely 1.66600 and promotion with the promotion variable (X2) with a tcount value of 1.706 ttable, namely 1.66600 with an R Square of 0.336. Thus, the independent variables, namely product knowledge and promotions, have a positive influence on the dependent variable in purchasing decisions of 33.6%.

ABSTRAK
Penelitian bertujuan untuk menganalisa dampak pengetahuan produk dan promosi terhadap keputusan pembelian labu madu di PT Askara Farm Indonesia. Metode penelitian menggunakan metode deskriptif kuantitatif dengan pendekatan survey dengan sampel sebanyak 75 orang. Pengumpulan data dilakukan dengan pengisian kuesioner untuk pengetahuan produk dan promosi dengan keputusan pembelian. Selanjutnya data yang terkumpul dianalisa dengan SPSS 16.0 for windows dengan tingkat kemaknaan (α) 0.05 dengan metode analisis data yang terdiri Uji Validitas, Uji Reliabilitas, Uji Asumsi Klasik (Uji Normalitas, Uji Heteroskedastisitas, Uji Multikolinearitas), Analisis Regresi Linear Berganda, Koefisien Determinasi dan Uji Hipotesis. Dari hasil penelitian diperoleh nilai thitung variabel pengetahuan produk (X1) sebesar 2,509 ≥ ttabel yaitu 1,66600 dan promosi dengan variabel promosi (X2) dengan nilai thitung sebesar 1,706 ≥ ttabel yaitu 1,66600 dengan R Square sebesar 0,336. Dengan demikian variabel bebas yaitu pengetahuan produk dan promosi mempunyai pengaruh yang positif terhadap variabel terikat keputusan pembelian sebesar 33,6%.