bluuebunny/crossref_metadata_2025_split huggingface dataset:
2.2  kW single-mode narrow-linewidth laser delivery through a hollow-core fiber
Authors: Cooper M. A. , Wahlen J. , Yerolatsitis S. , Cruz-Delgado D. , Parra D. , Tanner B. , Ahmadi P. , Jones O. , Habib Md. S. , Divliansky I. , Antonio-Lopez J. E. , Schülzgen A. , Amezcua Correa R. 
Published: September 2023

Antiresonant hollow-core fibers (AR-HCFs) have opened up exciting
possibilities for high-energy and high-power laser delivery because of
their exceptionally low nonlinearities and high damage thresholds.
While these fiber designs offer great potential for handling
kilowatt-class powers, it is crucial to investigate their performance
at multi-kW power levels. Until now, transmission of narrow-linewidth
single-mode lasers at multi-kW power levels through a HCF has not been
demonstrated, to our knowledge. Here, we present the delivery of a
record 2.2 kW laser power with an input spectral linewidth of
86 GHz, centered at 1080 nm, while maintaining 95%
transmission efficiency and beam quality (M2) of 1.03. This was achieved via a
104.5 m single-mode five-tube nested AR-HCF with
0.79 dB/km loss. Furthermore, we show power delivery of
1.7 kW with a spectral linewidth as narrow as 38 GHz
through the same fiber. Our results could lead to a new generation of
fiber-based laser beam delivery systems with applications in precision
machining, nonlinear science, directed energy, and power beaming over
fiber.
A Study of Dietary Patterns Derived by Cluster Analysis and Their Association With Metabolic Dysfunction-Associated Steatotic Liver Disease Severity Among Hispanic Patients
Authors: Zhang Xiaotao , Daniel Carrie R. , Soltero Valeria , Vargas Ximena , Jain Shilpa , Kanwal Fasiha , Thrift Aaron P. , Balakrishnan Maya 
Published: September 2023

INTRODUCTION:
Diet is a modifiable metabolic dysfunction-associated steatotic liver disease (MASLD) risk factor, but few studies have been conducted among Hispanic patients, despite the fact that MASLD prevalence and severity are highest among this ethnic subgroup. We aimed to identify prevalent dietary patterns among Hispanic patients using cluster analysis and to investigate associations with MASLD severity.

METHODS:
This cross-sectional analysis included 421 Harris County MASLD Cohort participants who self-reported Hispanic ethnicity and completed baseline food frequency questionnaires. All included patients had MASLD, diagnosed per standard clinical criteria. K-means analysis was used to identify clusters of patients sharing similar dietary habits. Multivariable adjusted logistic regression was used to estimate associations of dietary clusters with aminotransferases among the overall sample and with histologic steatosis, metabolic dysfunction-associated steatohepatitis, and fibrosis among a subsample of patients who underwent liver biopsy within 6 months of their baseline food frequency questionnaire (n = 186).

RESULTS:
We identified 2 clusters: a plant-food/prudent and a fast-food/meat pattern. The fast-food/meat pattern was associated with 2.47-fold increased odds (95% confidence interval 1.31–4.65) of more severe steatosis than the plant-food/prudent pattern after adjusting for demographics, metabolic score, physical activity, and alcohol (q = 0.0159). No significant association was observed between diet and aminotransferases, metabolic dysfunction-associated steatohepatitis, or fibrosis.

DISCUSSION:
Given the importance of sociocultural influences on diet, it is important to understand dietary patterns prevalent among Hispanic patients with MASLD. Using cluster analysis, we identified 1 plant-based pattern vs 1 distinct fast-food/meat-based pattern associated with detrimental effects among our population. This information is an important starting point for tailoring dietary interventions for Hispanic patients with MASLD.
“The Only Thing You Can’t Do Is Hear” 1
Authors: Ehriander Helene 
Published: September 2023

Set in the 1990s and engaging with issues current at that time, Hurt Go Happy tells two interconnected and thematically analogous stories: first, the struggle of deaf protagonist Joey Willis to be allowed to learn sign language and, second, twentieth-century experiments to teach American Sign Language to chimpanzees. The novel engages with the oralist/manualist debate and contends that being deaf and not being permitted to learn sign language is to be suspended between two cultures and denied agency. In its description of the different means of communication the novel gives voice to those who cannot always speak for themselves: children, the disabled and animals. The challenge is how to be a part of a society and a family without choosing one of the cultures over the other but naturally belonging to both. The chapter draws on theories from comparative literature, cultural studies, language studies and ethology.
La gare de Mons et le territoire
Authors: Bourez Olivier , Mawet Marc 
Published: September 2023

Tandis qu’ailleurs la recherche par le projet se cherche, Olivier Bourez et Marc Mawet fournissent, dans ce troisième numéro « hors série » des pages du laa, les arguments logiques et graphiques d’une exemplaire « critique par le projet ». Celle-ci consiste à montrer par le biais d’une proposition inédite qu’il existe une autre possibilité que celle d’abord envisagée, et qu’à l’aune de cette autre possibilité la première s’avère inadéquate ou inopportune.
La critique porte en l’occurrence sur la nouvelle gare de Mons, ouvrage en cours de réalisation dû à l’architecte et ingénieur espagnol Santiago Calatrava. De manière implacable, elle révèle une « occasion manquée » et, par là même, accuse les défauts d’une architecture autoréférentielle.
Olivier Bourez et Marc Mawet sont architectes. Le premier enseigne le projet d’architecture à la Faculté d’architecture, d’ingénierie architecturale, d’urbanisme de l’UCLouvain, le second enseigne la même matière à la Faculté d’architecture La Cambre Horta de l’ULB. Ensemble, ils dirigent l’agence d’architecture Matador (www.matador.be).
On intervals
Authors: Montalbetti Mario 
Published: September 2023

Le 15 avril 2019, la cathédrale Notre Dame de Paris prend feu ! L’incendie provoque, on le sait, un énorme émoi proportionnel à la charge des mémoires qui habitent l’édifice : le christianisme, les maîtres bâtisseurs du gothique, la Nation hypostasiée, la littérature et d’autres. Le président Macron et les très grandes fortunes de France tentent de transformer la catastrophe en effet d’aubaine et d’y capter quelques fragments de la hauteur morale qui leur manque.
Le 26 avril, 11 jours plus tard, Alain Badiou donne une conférence à l’Université de Louvain. Il revient sur l’incendie et analyse patiemment les multiples échos et effets de ce qu’il nomme un « accident architectural ». Il conclut sa conférence en énonçant abruptement, au titre de définition : “L’Architecture devrait être … comme une espèce d’intervalle violent entre le Réel et le Symbolique.” Le 20 février 2020, 10 mois plus tard, Mario Montalbetti donne une conférence à l’Université de Louvain qui s’arrime à la déclaration d’Alain Badiou qu’il commente à partir de ses propres positions, celle de poète et celle de linguiste.
Mario Montalbetti est linguiste, poète et essayiste. Docteur en linguistique (MIT, avec Noam Chomsky), il est professeur principal au Departamento de Humanidades de la Pontificia Universidad Catolica del Peru (PUCP). Il est membre fondateur de la revue Hueso Humero. Ses œuvres poétiques ont été réunies dans Lejos de mi decirles (Aldus, 2013). Il a publié également lacan arquitectura, avec Jean Stillemans (PUCP, 2009), Cualquier hombre es une isla (Fondo de Cultura Economica, 2014), El mas crudo invierno (Fondo de Cultura Economica, 2016), Cajas (Colecion Decir Arquitectura, PUCP, 2017), Epiciclos, avec Marc Belderbos ( Colecion Decir Arquitectura, PUCP, 2018), Notas para un seminario sobre Foucault (Fondo de Cultura Economica, 2018), El pensiamento del poema(Marginalia Editores, 2019). Les pages du laa ont publié en 2009 « Ce que Lacan n’a pas dit (sur l’architecture) est aussi organisé comme ce qu’il a dit (sur le langage) ».
Menopausal stage differences in endothelial resistance to ischemia‐reperfusion injury
Authors: Delgado Spicuzza Jocelyn M. , Proctor David N. , Thijssen Dick H. J. , Somani Yasina B. 
Published: September 2023

AbstractBackgroundIn postmenopausal women, reduced ovarian function precedes endothelial dysfunction and attenuated endothelial resistance to ischemia‐reperfusion (IR) injury. We hypothesized that IR injury would lower endothelial function, with premenopausal women demonstrating the greatest protection from injury, followed by early, then late postmenopausal women.MethodsFlow‐mediated dilation (FMD) was assessed at baseline and following IR injury in premenopausal (n = 11), early (n = 11; 4 ± 1.6 years since menopause), and late (n = 11; 15 ± 5.5 years since menopause) postmenopausal women.ResultsThere were significant group differences in baseline FMD (p = 0.007); post hoc analysis revealed a similar resting FMD between premenopausal (7.8% ± 2.1%) and early postmenopausal (7.1% ± 2.7%), but significantly lower FMD in late postmenopausal women (4.5% ± 2.3%). Results showed an overall decline in FMD after IR injury (p < 0.001), and a significant condition*time interaction (p = 0.048), with early postmenopausal women demonstrating the most significant decline in FMD following IR.ConclusionOur findings indicate that endothelial resistance to IR injury is attenuated in healthy early postmenopausal women.
Ventilatory efficiency in post‐COVID‐19 athletes
Authors: Komici Klara , Bencivenga Leonardo , Rengo Giuseppe , Bianco Andrea , Guerra Germano 
Published: September 2023

AbstractLimitation in exercise capacity has not been described in athletes affected by SARS‐CoV‐2 infection. However, patients who have recovered from COVID‐19 without cardiopulmonary impairment show exaggerated ventilatory response during exercise. Therefore, we aimed to evaluate the ventilatory efficiency (VEf) in competitive athletes recovered from COVID‐19 and to characterize the ventilation versus carbon dioxide relationship (VE/VCO2) slope in this population. Thirty‐seven competitive athletes with COVID‐19 were recruited for this study. All participants underwent spirometry, echocardiography, and cardiopulmonary exercise testing (CPET). z‐FVC values and end‐title pressure of CO2 (PETCO2) were lower in the third tertile compared with the first tertile: −0.753 ± 0.473 vs. 0.037 ± 0.911, p = 0.05; 42.2 ± 2.7 vs. 37.1 ± 2.5 mmHg, p < 0.01. VE/VCO2 slope was significantly correlated to maximal VCO2/VE and maximal VO2/VE: coefficient = −0.5 R2 = 0.58, p < 0.0001 and coefficient = −0.3 R2 = 0.16, p = 0.008. Competitive athletes affected by SARS‐CoV‐2 infection, without cardio‐respiratory disease sequel, may present ventilatory inefficiency (ViE), without exercise capacity limitation. FVC is higher in athletes with better ventilatory performance during exercise, and increased VE/VCO2 slope is inversely correlated to max VCO2/VE and max VO2/VE.
Body mass index evolution and ovarian function in adolescent girls who received GnRH agonist treatment for central precocious puberty or early and fast puberty
Authors: Buyukyilmaz Gonul , Koca Serkan Bilge , Adiguzel Keziban Toksoy , Gurbuz Fatih , Boyraz Mehmet 
Published: September 2023

Abstract

Objectives
Gonadotropin-releasing hormone agonist (GnRHa) has been used for central precocious puberty (CPP) or early and fast puberty. It was aimed to assess changes in body mass index (BMI), polycystic ovary syndrome (PCOS) frequency, and anti-Müllerian hormone (AMH) in girls who had been treated with GnRHa.

Methods
Fifty-eight adolescent girls treated with GnRHa for CPP or early and fast puberty (3.75 mg/28 days), between 2011 and 2015, were re-evaluated in 2020–2022 at least 2 years after menstruation. Hormonal analyses were compared with 51 healthy adolescents.

Results
In the GnRHa-treated group, a statistically significant increase was observed when the BMI standard deviation score (SDS) at the beginning of the treatment was compared with the BMI SDS at the end of the treatment (p=0.038). A statistically significant decrease was observed when the BMI SDS at the end of the treatment was compared with the BMI SDS in late adolescence (p=0.012). When the BMI SDS at the beginning of the treatment was compared with the BMI SDS in late adolescence, it was observed that there was no statistically significant difference (p=0.196). Of the 58 girls in the GnRHa-treated group, 8 (14 %) had PCOS. Serum AMH levels did not differ between the GnRHa-treated and the control group.

Conclusions
GnRHa treatment causes no adverse effect on BMI, at least in late adolescence. Girls treated with GnRHa were not found to be prone to developing PCOS. AMH levels were similar in the GnRHa-treated group as in the control group.
The antihypertensive felodipine shows synergistic activity with immune checkpoint blockade and inhibits tumor growth via NFAT1 in LUSC
Authors: Liang Si-Yu , Xiao Hong-Kai 
Published: September 2023

Abstract
This study aimed to explore the role and mechanism of felodipine in lung cancer therapy. Murine subcutaneous lung squamous cancer (LUSC) models constructed by KLN-205 cells were utilized to assess the effect of felodipine monotherapy and in combination with the programmed cell death protein 1 antibody (PD1ab) and cytotoxic T lymphocyte-associated antigen-4 (CTLA4ab). Immunohistochemistry analysis was subsequently applied to detect the number of CD8+ T cells and Ki67+ cells. Lastly, a series of in vitro and in vivo experiments were performed to evaluate the effects of felodipine on human LUSC cells and explore the preliminary mechanism underlying felodipine inhibition. The results revealed that felodipine monotherapy exerted a significant inhibitory effect on LUSC growth and synergistic antitumoral activity with PD1ab and CTLA4ab. Meanwhile, immunohistochemistry analysis displayed that felodipine promoted CD8+ T-cell infiltration and downregulated Ki67 expression in tumor cells. Moreover, in vitro and in vivo experiments utilizing human LUSC cells determined that felodipine impaired the proliferative and migratory abilities of cancer cells. In addition, TCGA data analysis uncovered that nuclear factor of activated T cell (NFAT1) expression was positively correlated with overall survival and disease-free survival. Finally, the cell counting kit-8 assay signaled that felodipine might suppress tumor growth by modulating NFAT1.
Cooperatives in insolvency and liquidation - an overview of recent case law developments (2021 - 2023)
Authors: Kling Michael 
Published: September 2023

Zusammenfassung
Der vorliegende Beitrag nimmt die neuere Rechtsprechung zu Genossenschaften in Insolvenz und Liquidation zum Anlass, die Grundsätze der fehlerhaften Gesellschaft in den Blick zu nehmen. Deren drastische Rechtsfolgen - Fortgeltung der Pflicht der Genossenschaftsmitglieder zur Zahlung rückständiger Einlagen und Kündigungsmöglichkeit der Gesellschaft lediglich für die Zukunft - werden durch diese Rechtsprechung erneut vollumfänglich bestätigt. Umstritten ist jedoch die Befugnis des Insolvenzverwalters zur Geltendmachung rückständiger Pflichteiträge, sofern das Gesellschaftsvermögen zur Befriedigung der Gesellschaftsgläubiger ausreicht. Ferner wird untersucht, ob investierende Mitglieder ihren Zeichnungsschaden gegenüber dem für die Gründungsprüfung zuständigen genossenschaftlichen Prüfverband geltend machen können. Diese Möglichkeit scheitert regelmäßig an den sehr strengen Haftungsvoraussetzungen.
Da tutela à luta pela autonomia
Authors: Bronz Deborah 
Published: September 2023

Ao considerar a importância da pesca artesanal para a economia familiar e a reprodução de modos de vida e práticas culturais de uma grande quantidade de comunidades situadas em todo território nacional, este ensaio procura recuperar a forma como pescadores e pescadoras se relacionaram historicamente com o Estado brasileiro. A análise das políticas governamentais e regulações da pesca até os dias de hoje pode iluminar nossa compreensão sobre os modos como estes/as foram se constituindo como sujeitos das políticas de Estado e formulando as pautas de sua luta por direitos. Diferentes direcionamentos alicerçaram as políticas governamentais da pesca ao longo do tempo. Mais recentemente, a vinculação entre as políticas da pesca e as políticas de proteção ambiental se apresenta como uma alternativa importante à manutenção dos modos de vida tradicionais ligados à pesca artesanal. A análise mais abrangente das políticas estatais e das formas de organização política de pescadores/as é complementada pela visão particular de três importantes lideranças, pessoas que participaram ativamente das lutas pelo reconhecimento de seus direitos no Brasil.
Recommendations Emerging from Carbon Emissions Estimations of the Society for Neuroscience Annual Meeting
Authors: Kay Caroline , Kuper Rob , Becker Elizabeth A. 
Published: September 2023

AbstractThe annual Society for Neuroscience (SfN) meeting yields significant, measurable impacts that conflict with the environmental commitment of the Society and the Intergovernmental Panel on Climate Change (IPCC) recommendations to address the climate emergency (IPCC, 2018). We used 12,761 presenters’ origins, two online carbon calculators, and benchmark values to estimate 2018 meeting-related travel, event venue operations, and hotel accommodation emissions. Presenters’ conference travel resulted in between 17,298 and 8690 tons of atmospheric carbon dioxide (t CO2), with or without radiative forcing index factors. Over 92% of authors traveled by air and were responsible for >99% of total travel-related emissions. Extrapolations based on 28,691 registrants yielded between 69,592.60 metric tons of carbon dioxide equivalents (t CO2e) and 38,010.85 t CO2from travel. Comparatively, authors’ and registrants’ hotel accommodation emissions equaled 429 and 965 t CO2e, whereas operation of the San Diego Convention Center equaled ∼107 t CO2e. We relate SfN meeting-related emissions to potential September Arctic Sea ice loss, labor productivity loss in lower-income equatorial countries, and future temperature-related deaths. We estimate emissions reductions of between 23% and 78% by incentivizing between 10% and 50% of the most distant registrants to attend virtually or connecting between two and seven in-person hubs virtually. Completely virtual meetings may yield a reduction of >99% relative to centralized in-person meetings and increase participation of women, queer and transgender scientists, and scientists from low- and middle-income countries. We strongly recommend adopting alternative meeting modes such as four or more in-person global hubs connected virtually by 2030 and fully virtual by 2050.
Causalidad y posicionamientos en el discurso de la historia escolar en español
Authors: Leiva Natalia , Oteíza Teresa 
Published: September 2023

En la construcción discursiva de la causalidad confluye el uso de una serie de recursos que van mucho más allá de los denominados “conectores causales” en la tradición lingüística española. Estudios en español han mostrado que la conexión puede realizarse implícita y explícitamente a través de diversas configuraciones. Algunas de estas configuraciones, además de realizar conexión, implican determinados posicionamientos interpersonales. El objetivo de este artículo es caracterizar la interacción entre los significados de conexión y significados interpersonales en la construcción de la causalidad histórica. Para ello, se analizan las secuencias causales en fragmentos provenientes de un texto escolar chileno de Historia para tercer año de enseñanza secundaria, desde una perspectiva semántico-discursiva utilizando la lingüística sistémico-funcional. El análisis de las secuencias permite observar que el sistema de conexión interactúa con los subsistemas interpersonales de compromiso y gradación. En relación con el subsistema de compromiso, las conexiones realizadas verbalmente (p. ej. A permitió B) juegan un rol en el cierre o apertura del espacio dialógico. Respecto del subsistema de gradación, las mismas conexiones permiten agudizar o suavizar la actualización de la conexión causal. Desde una mirada multifuncional del lenguaje, se concluye que la construcción de la causalidad genera ensambles con significados lógicos e interpersonales que son relevantes en la interpretación del pasado.
Enhancing Handwriting in the Peruvian Educational Context: Design of an Interactive Web Platform
Authors: Lida Violeta Asencios-Trujilo , Lucia Asencios-Trujillo , Carlos Jacinto La Rosa-Longobardi , Djamila Gallegos-Espinoza , Cristina Piñas-Livia , Rosa Perez- Siguas , Hernan Matta-Solis 
Published: September 2023

The main objective of this research work is to design a web platform so that through its use they can learn to write, it is aimed at a general public regardless of their age. A Design Thinking methodology was used since it was found to be adequate to explain each stage of the research in their respective phases of the methodology. On the other hand, a survey was conducted with 15 people from an Alternative Basic Educational Center (CEBA) to find out if they were willing to use a web platform to learn to write.
Finally, it was concluded that it is necessary to take advantage of technological advances for problems that may occur in the field of education and have solutions through its use.
A New Automatic Watercolour Painting Algorithm Based on Dual Stream Image Segmentation Model with Colour Space Estimation
Authors: Zhou Ye , Sirivesmas Veerawat , Joneurairatana Eakachat , Simatrang Sone 
Published: September 2023

Image processing plays a crucial role in automatic watercolor painting by manipulating the digital image to achieve the desired watercolor effect. segmentation in automatic watercolor painting algorithms is essential for region-based processing, color mixing and blending, capturing brushwork and texture, and providing artistic control over the final result. It allows for more realistic and expressive watercolor-like paintings by processing different image regions individually and applying appropriate effects to each segment. Hence, this paper proposed an effective Dual Stream Exception Maximization (DSEM) for automatic image segmentation. DSEM combines both color and texture information to segment an image into meaningful regions. This approach begins by converting the image from the RGB color space to a perceptually-based color space, such as CIELAB, to account for variations in lighting conditions and human perception of color. With the color space conversion, DSEM extracts relevant features from the image. Color features are computed based on the values of the color channels in the chosen color space, capturing the nuances of color distribution within the image. Simultaneously, texture features are derived by computing statistical measures such as local variance or co-occurrence matrices, capturing the textural characteristics of the image. Finally, the model is applied over the deep learning model for the classification of the color space in the painting. Simulation analysis is performed compared with conventional segmentation techniques such a CNN and RNN. The comparative analysis states that the proposed DSEM exhibits superior performance compared to conventional techniques in terms of color space estimation, texture analysis and region merging. The performance of classification with DSEM is ~12% higher than the conventional techniques.