bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prescribed Opioid Dosages, Payer Type, and Self-Reported Outcomes After Surgical Procedures in Michigan, 2018-2020
Authors: Breuler Christopher J. , Shabet Christina , Delaney Lia D. , Brown Craig S. , Lai Yen-Ling , Brummett Chad M. , Bicket Mark C. , Englesbe Michael J. , Waljee Jennifer F. , Howard Ryan A. 
Published: July 2023

ImportanceCollaborative quality improvement (CQI) models, often supported by private payers, create hospital networks to improve health care delivery. Recently, these systems have focused on opioid stewardship; however, it is unclear whether reduction in postoperative opioid prescribing occurs uniformly across health insurance payer types.ObjectiveTo evaluate the association between insurance payer type, postoperative opioid prescription size, and patient-reported outcomes in a large statewide CQI model.Design, Setting, and ParticipantsThis retrospective cohort study used data from 70 hospitals within the Michigan Surgical Quality Collaborative clinical registry for adult patients (age ≥18 years) undergoing general, colorectal, vascular, or gynecologic surgical procedures between January 1, 2018, and December 31, 2020.ExposureInsurance type, classified as private, Medicare, or Medicaid.Main Outcomes and MeasuresThe primary outcome was postoperative opioid prescription size in milligrams of oral morphine equivalents (OME). Secondary outcomes were patient-reported opioid consumption, refill rate, satisfaction, pain, quality of life, and regret about undergoing surgery.ResultsA total of 40 149 patients (22 921 [57.1%] female; mean [SD] age, 53 [17] years) underwent surgery during the study period. Within this cohort, 23 097 patients (57.5%) had private insurance, 10 667 (26.6%) had Medicare, and 6385 (15.9%) had Medicaid. Unadjusted opioid prescription size decreased for all 3 groups during the study period from 115 to 61 OME for private insurance patients, from 96 to 53 OME for Medicare patients, and from 132 to 65 OME for Medicaid patients. A total of 22 665 patients received a postoperative opioid prescription and had follow-up data for opioid consumption and refill. The rate of opioid consumption was highest among Medicaid patients throughout the study period (16.82 OME [95% CI, 12.57-21.07 OME] greater than among patients with private insurance) but increased the least over time. The odds of refill significantly decreased over time for patients with Medicaid compared with patients with private insurance (odds ratio, 0.93; 95% CI, 0.89-0.98). Adjusted refill rates for private insurance remained between 3.0% and 3.1% over the study period; adjusted refill rates among Medicare and Medicaid patients decreased from 4.7% to 3.1% and 6.5% to 3.4%, respectively, by the end of the study period.Conclusions and RelevanceIn this retrospective cohort study of surgical patients in Michigan from 2018 to 2020, postoperative opioid prescription size decreased across all payer types, and differences between groups narrowed over time. Although funded by private payers, the CQI model appeared to have benefitted patients with Medicare and Medicaid as well.
Characteristics of topographical location and spatial composition on villages on Kikaijima Island, Nansei Islands: Reconstructing spatial composition of villages immediately before and after World War II
Authors: Kamata Seishi , Yamamoto Takatsugu , Urayama Takakazu , Shibuya Sizuaki , Saiki Takahito 
Published: July 2023

AbstractThe purpose of this study was to reconstruct the spatial characteristics of the villages on Kikaijima Island immediately before and after World War II to examine the characteristics of these spatial characteristics within the context of the topographical situation of the villages. In this study, we clarified the commonalities and differences of the location and spatial composition of the villages by analyzing aerial photographs of all of the villages on Kikaijima Island by the US military immediately before and after World War II.
Robust virtual sensors design for linear and nonlinear systems under external disturbances
Authors: Zhirabok Alexey , Zuev Alexander , Filaretov Vladimir , Protcenko Alexander , Chung Il Kim 
Published: July 2023

SummaryThe problem of robust virtual sensors design in linear and nonlinear dynamic systems is studied. To design such sensors, two different canonical forms are used: identification and Jordan canonical forms. The problems generally are solved in three steps: at the first step, the linear model invariant with respect to the disturbance is designed; at the second step, a possibility to take into account the nonlinear term and to estimate the given variable is checked; finally, stability of the observer is obtained. The relations allowing to design virtual sensor of minimal dimension estimating the prescribed component of the state vector of the system are obtained. The problem of virtual sensor location is studied and solved. The theoretical results are illustrated by the example of three tank system.
Deep‐MSIM: Fast Image Reconstruction with Deep Learning in Multifocal Structured Illumination Microscopy
Authors: Liao Jianhui , Zhang Chenshuang , Xu Xiangcong , Zhou Liangliang , Yu Bin , Lin Danying , Li Jia , Qu Junle 
Published: July 2023

AbstractFast and precise reconstruction algorithm is desired for for multifocal structured illumination microscopy (MSIM) to obtain the super‐resolution image. This work proposes a deep convolutional neural network (CNN) to learn a direct mapping from raw MSIM images to super‐resolution image, which takes advantage of the computational advances of deep learning to accelerate the reconstruction. The method is validated on diverse biological structures and in vivo imaging of zebrafish at a depth of 100 µm. The results show that high‐quality, super‐resolution images can be reconstructed in one‐third of the runtime consumed by conventional MSIM method, without compromising spatial resolution. Last but not least, a fourfold reduction in the number of raw images required for reconstruction is achieved by using the same network architecture, yet with different training data.
Pure Organic AIE Nanoscintillator for X‐ray Mediated Type I and Type II Photodynamic Therapy
Authors: Yu Yuewen , Xiang Lisha , Zhang Xuanwei , Zhang Le , Ni Zhiqiang , Zhu Zhong‐Hong , Liu Yubo , Lan Jie , Liu Wei , Xie Ganfeng , Feng Guangxue , Tang Ben Zhong 
Published: July 2023

AbstractX‐ray induced photodynamic therapy (X‐PDT) circumvents the poor penetration depth of conventional PDT with minimal radio‐resistance generation. However, conventional X‐PDT typically requires inorganic scintillators as energy transducers to excite neighboring photosensitizers (PSs) to generate reactive oxygen species (ROS). Herein, a pure organic aggregation‐induced emission (AIE) nanoscintillator (TBDCR NPs) that can massively generate both type I and type II ROS under direct X‐ray irradiation is reported for hypoxia‐tolerant X‐PDT. Heteroatoms are introduced to enhance X‐ray harvesting and ROS generation ability, and AIE‐active TBDCR exhibits aggregation‐enhanced ROS especially less oxygen‐dependent hydroxyl radical (HO•−, type I) generation ability. TBDCR NPs with a distinctive PEG crystalline shell to provide a rigid intraparticle microenvironment show further enhanced ROS generation. Intriguingly, TBDCR NPs show bright near‐infrared fluorescence and massive singlet oxygen and HO•− generation under direct X‐ray irradiation, which demonstrate excellent antitumor X‐PDT performance both in vitro and in vivo. To the best of knowledge, this is the first pure organic PS capable of generating both 1O2 and radicals (HO•−) in response to direct X‐ray irradiation, which shall provide new insights for designing organic scintillators with excellent X‐ray harvesting and predominant free radical generation for efficient X‐PDT.
Recent Progress on Natural Clay Minerals for Lithium‐Sulfur Batteries
Authors: Yang Liu , Yang Xin , Xia Feng , Gong Yifei , Li Faxue , Yu Jianyong , Gao Tingting , Li Yiju 
Published: July 2023

AbstractLi−S batteries with high energy density have the potential to become a viable alternative to Li‐ion batteries. However, Li−S batteries still face several challenges, including the shuttle effect, low conversion kinetics, and Li dendrite growth. Natural clay minerals with porous structures, abundant Lewis‐acid sites, high mechanical modulus, and versatile structural regulation show great potential for improving the performance of Li−S batteries. However, so far, relevant reviews focusing on the applications of natural clay minerals in Li−S batteries are still missing. To fill the gap, this review first presents an overview of the crystal structures of several natural clay minerals, including 1D (halloysites, attapulgites, and sepiolite), 2D (montmorillonite and vermiculite), and 3D (diatomite) structures, providing a theoretical basis for the application of natural clay minerals in Li−S batteries. Subsequently, research advancements in the natural clay‐based energy materials in Li−S batteries have been comprehensively reviewed. Finally, the perspectives concerning the development of natural clay minerals and their applications in Li−S batteries are provided. We hope this review can provide timely and comprehensive information on the correlation between the structure and function of natural clay minerals in Li−S batteries and offer guidance for material selection and structure optimization of natural clay‐based energy materials.
Affinity to mnemonic features of social media: Antecedent and consequences
Authors: Mookherjee Satadruta , Mohanty Smaraki , Mukherjee Sourjo 
Published: July 2023

AbstractThis research explores consumer loneliness and its resulting preference for mnemonic features as the psychological antecedents of social media use and studies its consequence on consumer behavior. To test our hypotheses, we conducted a survey with a large sample (N = 1307) and analyzed the data using PLS structural equation modeling method. We show that individuals with higher (vs. lower) feelings of loneliness show a lower (vs. higher) affinity to mnemonic features of social media platforms, making them more likely to use Snapchat (vs. Facebook). This effect persists after controlling for demographic factors (such as age and gender) and other known motivations behind social media choice. These two groups of social media users also exhibit different types of consumer behavior resulting from their underlying affinity to mnemonic features. Snapchat users tend to be more variety‐seeking and prefer newer brands (vs. established brands) than Facebook users. Our research contributes to the literature on the adoption of social media platforms by studying an important individual difference variable and integrating the concept of mnemonic features of social media as a key driving factor in that choice. The findings can give managers essential insights into the usership of social media platforms and help them select the right platform for their social media campaigns.
Investigating the changes of texture, physicochemical properties, microbial diversity, and volatile compounds of quinoa fresh noodles during storage time
Authors: Wang Zinan , Liang Shan , Zhang Min 
Published: July 2023

AbstractBackgroundQuinoa was suggested to substitute in noodles with positive effects of cardiovascular disease, metabolic, and gastrointestinal systems. However, quinoa fresh noodles (QFN) were hard to preserve but constrain industrial production. The deteriorative changes in the quality and relative parameters of QFN at 25 ± 1°C are lacking and needed to investigate.FindingsIn this study, QFN was sampled every 12 h at 25 ± 1°C, and found that the total plate count exceeded safety limit (5 log10 CFU/g) in 24 h. Bacillus, Staphylococcus, Aspergillus, and Filobasidium were the dominant spoilage microorganisms, where Bacillus was significantly increased and accounted over 90% of bacteria after spoilage. The volatile compounds changed significantly, where aldehydes decreased from 58.25% to 30.09%, while easters and alcohols increased from 2.29% to 14.84%, and 7.78% to 20.28% separately. With increasing of storage time, the water content and water activity decreased. Besides, strongly bound water decreased from 12.51% to 7.63%, weakly bound water and free water increased. The color of QFN turned to dark and red, where a value increased from 2.11 to 3.82, while L value decreased from 75.20 to 64.56. pH of QFN also decreased during storage. The quality index of QFN was qualified with decreased texture properties (hardness, springiness, and chewiness) and significantly increased cooking loss rate (8.65%–12.74%) and cooked broken rate (0%–26.67%).ConclusionsThe storage time of QFN was 24 h at 25 ± 1°C. The textural changes and certain indexes changed significantly after spoilage. And relative indexes of QFN qualities presented significant correlation with microorganisms.Significance and NoveltyBacillus in QFN may contribute significant changes in spoilage. The correlation analysis figured out the possible reasons for qualities changes of QFN.
Osteomyelitis with abscess associated with acute closed upper humerus fracture in an adult: A case report
Authors: Skedros John G. , Smith Tyler R. , Cronin John T. 
Published: July 2023

Key Clinical MessageA 64‐year‐old female presented with malaise and fever 11 days after a closed, minimally displaced humerus surgical neck fracture. MR imaging revealed an abscess around the fracture, which is a very rare occurrence in adults. Two open debridements and IV antibiotics eradicated the infection. Reverse total shoulder arthroplasty was eventually performed for fracture nonunion.
A diagnostic challenge; pelvic solitary fibrous tumor (SFT) mimicking Peri‐Anal gastrointestinal stromal tumor (GIST): A case report
Authors: Yazdi Seyed Amir Miratashi , Roudsari Payvand Parhizkar , Amoli Hadi Ahmadi , Hajebi Reza 
Published: July 2023

Key Clinical MessageThe study reports a rare case of pelvic solitary fibrous tumor (SFT) that was initially considered as a peri‐anal gastrointestinal stromal tumor due to similar radiologic/pathologic features. SFT diagnosis can be challenging due to its rarity and wide range of diagnoses that must be ruled out precisely.AbstractSolitary fibrous tumors (SFTs) are rare tumors that can occur in any part of the body. Although usually benign, malignant SFTs have been reported, especially outside the lungs. Radiology can help with diagnosis, but immunohistochemistry is necessary to distinguish SFTs from other possible diagnoses such as gastrointestinal stromal tumors (GISTs). This study presents a rare case of pelvic SFT initially considered to be a peri‐anal GIST, highlighting the importance of accurate diagnosis given the rarity of SFTs and the need to rule out other potential diagnoses.
Incidentally diagnosed multiple intradural extramedullary spinal hydatidosis in a young adult: A case report and review of the literature
Authors: Ahmadi Seyyed Mostafa , Meibodi Keyvan Tayebi , Raeesi Neda , Bitaraf Mohammad Ali , Iranmehr Arad 
Published: July 2023

Key Clinical MessageAlthough quite rare, vertebral hydatidosis should always be considered as a differential diagnosis for spinal presentations, particularly in endemic areas for echinococcosis.AbstractIn this paper, we report a rare case of asymptomatic multiple intradural, extramedullary spinal hydatidosis, incidentally diagnosed in a patient with signs and symptoms of a true protruded disc. Although quite rare, vertebral hydatidosis should always be considered as a differential diagnosis for spinal presentations, particularly in endemic areas for echinococcosis.
Chiral diketopyrrolo[3,4‐c]pyrrole‐based oligothiophenes: Synthesis and characterization of aggregated states in solution and thin films
Authors: Albano Gianluigi , Aronica Laura Antonella , Pescitelli Gennaro , Di Bari Lorenzo 
Published: July 2023

AbstractIn this work, we synthesized a family of three structurally related chiral oligothiophenes containing a 1,4‐diketo‐3,6‐diarylpyrrolo[3,4‐c]pyrrole (DPP) unit as the central core; functionalized with the same (S)‐3,7‐dimethyl‐1‐octyl chains on the nitrogen atoms of lactam moieties, they only differ in the number of lateral thiophene units. The aggregation modes of these π‐conjugated chiral systems were evaluated by means of UV–Vis absorption and ECD spectroscopies in conditions of solution aggregation (CHCl3/MeOH mixtures) and as thin films, describing in particular the impact of the π‐conjugation length on the chiroptical properties. Interestingly, we found that the variable number of thiophene units attached to the DPP core affects not only the propensity to aggregation but also the aggregates' helicity. ECD revealed information about the supramolecular arrangement of these molecules, that one would not obtain by using conventional optical spectroscopy and microscopy techniques. Thin film samples revealed very different aggregation modes with respect to solution aggregates, casting doubts on the common assumption that these latter may serve as simple models of the former ones.
Digital, interactive, colorful – interactive visualizations about color perception and organic colorants for chemistry lessons
Authors: Zerouali Amina , Werner Bernard , Lewalter Doris , Koenen Jenna 
Published: July 2023

AbstractDie Wahrnehmung von Licht und Farbe ist ein omnipräsentes Phänomen des alltäglichen Lebens. Daher entwickeln Schülerinnen und Schüler frühzeitig eigene Konzepte und Vorstellungen über die Natur dieser Phänomene. Diese Konzepte bzw. Vorstellungen beeinflussen die Art und Weise, wie Schülerinnen und Schüler Licht und Farbe wahrnehmen und verstehen. Bereits bestehende Konzepte beeinflussen den Lernprozess maßgeblich. Daher gilt es, diese bei der Gestaltung von Lehr‐/Lernmaterialien zu berücksichtigen, um diese Konzepte gezielt zu adressieren. Eine Methode, den Lernprozess zu unterstützen, ist die Verwendung von interaktiven Visualisierungen, die es Schülerinnen und Schülern ermöglichen, Phänomene gezielt zu erfahren und ihre bestehenden Konzepte zu hinterfragen und/oder zu erweitern. Der nachfolgende Artikel befasst sich daher mit der Konzeption und Entwicklung von interaktiven Visualisierungen zum Thema Licht und Farbe und präsentiert Implementierungsmöglichkeiten in den Chemieunterricht.
Solid State Zinc and Aluminum ion batteries: Challenges and Opportunities
Authors: Guo Yuqi , Lim Gwendolyn J. H. , Verma Vivek , Cai Yi , Chua Rodney , Nicholas Lim J. J. , Srinivasan Madhavi 
Published: July 2023

AbstractSolid‐state zinc ion batteries (ZIBs) and aluminum‐ion batteries (AIBs) are deemed as promising candidates for supplying power in wearable devices due to merits of low cost, high safety, and tunable flexibility. However, their wide‐scale practical application is limited by various challenges, down to the material level. This Review begins with elaboration of the root causes and their detrimental effect for four main limitations: electrode‐electrolyte interface contact, electrolyte ionic conductivity, mechanical strength, and electrochemical stability window of the electrolyte. Thereafter, various strategies to mitigate each of the described limitation are discussed along with future research direction perspectives. Finally, to estimate the viability of these technologies for wearable applications, economic‐performance metrics are compared against Li‐ion batteries.
Slowing down of charged particles in the dusty plasmas with a non‐thermal velocity α‐distribution
Authors: Wang Yu , Du Jiulin 
Published: July 2023

AbstractThe slowing down of a charged particle beam passing through the dusty plasma with a non‐thermal velocity α‐distribution is studied. By using the Fokker‐Planck collision theory, we derive the deceleration factor and slowing down time and make the numerical analyses. We show that the non‐thermal velocity α‐distributions of the plasma components have a significant effect on the slowing down. With increase of the mean velocity, the deceleration factor increases rapidly, reaches a peak and then decreases gradually. And the entire peak of the deceleration factor moves generally to the right with the increase of the α‐parameter. The slowing down time decreases with the increase of the non‐thermal α‐parameter, and so the slowing down time in the non‐thermal dusty plasma is generally less than that in a Maxwellian one.
Biotic and abiotic factors shaping bat activity in Maryland soybean fields
Authors: Maynard Lauren D. , Ford W. Mark , Parker John D. , Whitehead Susan R. 
Published: July 2023

AbstractBats are important pest control agents in agriculture. Yet, the underlying fine‐scale biotic and abiotic mechanisms that drive their foraging behaviors and responses to insect outbreaks are unclear. Herbivore‐induced plant volatiles (HIPVs) can attract both invertebrate and vertebrate natural enemies that use the chemical plant cues to locate insect prey. The ability of HIPVs to attract multiple species raises the question of whether they may also be a biotic factor influencing insectivorous bat activity. Additionally, abiotic factors, such as weather conditions, can affect bat activity in agricultural settings, but little is known about how bats respond to shifting environmental conditions on short timescales in this landscape context. Using a model crop system, soybean (Glycine max), our study asked three questions: (1) Which bat species are active in eastern Maryland soybean fields? (2) Is insectivorous bat activity affected by naturally occurring soybean HIPVs and/or synthetic soybean HIPVs (indole or farnesene)? (3) How is insectivorous bat activity affected by hourly weather conditions in this landscape? In soybean fields in eastern Maryland, we created paired treatment plots: HIPV plots (damaged plants or synthetic HIPV dispensers) and control plots (undamaged plants or empty dispensers). We measured bat activity using ultrasonic recorders, summarizing hourly and nightly activity, and detected 10 total species. The most abundant species were big brown/silver‐haired bats (Eptesicus fuscus/Lasionycteris noctivagans). Bat activity did not significantly differ between control and HIPV plots in any of the three experiments. Thus, our results do not support our expectation that bats in eastern Maryland use soybean HIPVs to locate insect prey. However, bat activity did increase with increasing average hourly temperature and wind speed. This initial study of bats and HIPVs, as well as the fine‐scale examination of weather conditions on bat activity, may serve as a guide for future research on bat–plant interactions that can support the development of new strategies for sustainable pest management.
Discrimination for geographical origin of Panax quinquefolius L. using UPLC Q‐Orbitrap MS‐based metabolomics approach
Authors: Pang Shifeng , Piao Xiangmin , Zhang Xiaohao , Chen Xiaolin , Zhang Hao , Jin Yinping , Li Zheng , Wang Yingping 
Published: July 2023

AbstractAmerican ginseng, Panax quinquefolius L., is an important medicinal plant with multiple pharmacological effects and high nutritional value. American ginseng from different geographical origins varies in quality and price. However, there was no approach for discriminating American ginseng from different geographical origins to date. In this study, a metabolomic method based on the UPLC–Orbitrap fusion platform was established to comprehensively determine and analyze metabolites of American ginseng from America and Canada, Heilongjiang, Jilin, Liaoning, and Shandong provinces in China. A total of 382 metabolites were detected, including 230 saponins, 30 amino acids and derivatives, 27 organic acids and derivatives, 25 lipids, 17 carbohydrates and derivatives, 10 phenols, 8 nucleotides, and derivatives, as well as 35 other metabolites. Metabolite differences between North America and Asia producing areas were more obvious than within Asia. Twenty metabolites, contributed most to the differentiation of producing areas, were identified as potential markers with prediction accuracy higher than 91%. The results provide new insights into the metabolite composition of American ginseng from different origins, which will help discriminate origins and promote quality control of American ginseng.