bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Prediction of Cardio Vascular Disease (CVD) from Diabetic Retinopathy using improvised deep Belief Network (I-DBN) with Optimum feature selection technique
Authors: Revathi T. K. , Sathiyabhama B. , Kaliraj S , Sureshkumar Vidhushavarshini 
Published: January 2025

Abstract
Cardio Vascular Disease (CVD) is one of the leading causes of mortality and it is estimated that 1 in 4 deaths happens due to it. The disease prevalence rate becomes higher since there is an inadequate system/model for predicting CVD at an earliest. Diabetic Retinopathy (DR) is a kind of eye disease was associated with increasing risk factors for all-causes of CVD events. The early diagnosis of DR plays a significant role in preventing CVD. However, there are many works have been carried out on classification of the disease but they focused less on feature selection and increasing the accuracy of the model. The proposed work introduces Improvised Deep Belief Network named I-DBN to resolve the above mentioned problems and mainly to concentrate on improving the entire performance of the model leading to the unbiased output. We used Principal Component Analysis (PCA) and Particle Swarm Optimization (PSO) algorithm for feature extraction and selection respectively. Five performance metrics have been used to assess the proposed model. The results of I-DBN outperform other state-of-the-art methods. The result validation ensures that I-DBN can deliver trustworthy recommendations to doctors to treat the patients by enhancing the accuracy of CVD prediction up to 98.95%.
Effects of respiratory sarcopenia on the postoperative course in elderly lung cancer patient: a retrospective study
Authors: Han Dong Jae , Na Kwon Joong , Yun Taeyoung , Park Ji Hyeon , Na Bubse , Park Samina , Lee Hyun Joo , Park In Kyu , Kang Chang Hyun , Kim Young Tae 
Published: January 2025

Abstract

Objectives
Recently, sarcopenia has been linked to unfavorable outcomes in various surgical procedures, including lung cancer surgery. This study aimed to investigate the impact of respiratory sarcopenia (RS) on postoperative and long-term outcomes in elderly patients undergoing lung cancer surgery.

Methods
This retrospective study included patients aged 70 years and older who underwent lobectomy with curative intent for lung cancer between 2017 and 2019. RS was defined as having values below the median for both the L3 skeletal muscle index, measured from preoperative PET-CT images, and peak expiratory flow (PEF). An inverse probability of treatment weighting (IPTW) approach was applied to balance covariates between the RS and non-RS groups. Baseline characteristics and postoperative outcomes were compared between groups using t-tests and chi-square tests. Kaplan–Meier curves and log-rank tests were used to compare overall and recurrence-free survival. Multivariable logistic regression analysis incorporating IPTW weights was performed to assess the impact of RS on respiratory complications.

Results
A total of 509 patients were included, of whom 123 (24.2%) had RS. After IPTW adjustment, baseline characteristics, including pulmonary function, were similar between the RS and non-RS groups. All patients underwent lobectomy, with 78.8% of the RS group and 80.9% of the non-RS group undergoing minimally invasive surgery. The RS group had a significantly higher rate of respiratory complications compared to the non-RS group (14.5% vs. 7.7%, p = 0.041). Multivariable logistic regression analysis showed that male sex (odds ratio = 15.2, p < 0.01) and lower DLCO (odds ratio = 0.96, p < 0.01) were significantly associated with respiratory complications, whereas RS did not show a significant association (p = 0.05). No significant differences were found in overall survival (p = 0.11) or recurrence-free survival (p = 0.51) between the groups.

Conclusions
In this study, RS had a limited impact on both postoperative and long-term outcomes in elderly patients undergoing lung cancer surgery. These findings suggest that other factors, such as DLCO and male sex, may play a more prominent role in predicting respiratory complications.
Intraoperative vascular anastomosis occlusion due to cold agglutinin disease during brain surgery: a case report
Authors: Kitamura Kazuma , Nakanishi Mayumi , Fukuoka Naokazu , Tanabe Kumiko , Kamiya Yoshinori 
Published: January 2025

Abstract

Background
Cold agglutinin disease (CAD) is an autoimmune hemolytic anemia that induces blood coagulation and hemolysis upon exposure to cold temperatures. Strict temperature control is essential to mitigate these effects, especially during surgical procedures where hypothermia is possible.

Case presentation
A 57-year-old male, 165 cm and 72 kg, diagnosed with CAD, underwent cerebral vascular anastomosis. Intraoperatively, mean arterial pressure was maintained at or above 65 mmHg with phenylephrine administration, while body temperature was rigorously controlled between 36.5 °C and 37.5 °C using forced-air warming blankets and heated intravenous infusions. Despite these measures, thrombotic occlusion occurred, necessitating surgical thrombus removal, intravenous heparin administration, and irrigation of the surgical field with warmed saline followed by re-anastomosis. The anastomosis remained patent without recurrence of thrombus formation thereafter.

Conclusion
Preventing hypothermia is extremely important in the anesthesia management of CAD patients. However, careful attention must also be paid to temperature regulation in the surgical field.
Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review
Authors: Komorowski Marcin , Janiszewski Michał , Pelczarska Aleksandra , Kaczorowski Rafal , Forenc Tomasz , Hunia Jaromir , Górny Julia , Jurek Jonasz , Kapciak Alicja 
Published: January 2025

Introduction: Caffeine, a well-known stimulant, is commonly used by athletes to enhance performance across various sports, including combat sports. Its ergogenic properties, such as improved strength, endurance, and cognitive function, have been well documented in the literature. This paper explores the effects of caffeine supplementation on combat sports, specifically in disciplines such as judo, jiu-jitsu, taekwondo, and boxing. The impact of different doses of caffeine on performance in these sports is examined, along with potential risks, limitations, and considerations for its use.
Aim of Study: The primary aim of this study is to analyze the effects of caffeine on performance in combat sports, considering various factors such as optimal dosage, timing, and the impact of habitual caffeine consumption. Additionally, this paper evaluates the potential adverse effects, including anxiety, sleep disturbances, and cardiovascular concerns, as well as the considerations regarding caffeine’s status as a banned substance in sports.
Material and methods: A review of the literature on caffeine and its effect was performed using the PubMed database.
Results and Conclusions: Caffeine supplementation consistently enhances performance in combat sports. Doses ranging from 3–6 mg/kg were found to improve strength, endurance, and reaction times across various combat sports, with higher doses being more effective for elite athletes. However, habitual caffeine consumption may diminish responsiveness to caffeine’s ergogenic effects. Caffeine’s potential adverse effects, such as anxiety, insomnia, and increased heart rate, were reported, with gender differences in sensitivity. While caffeine’s ergogenic effects are well-established, its use should be personalized, considering individual responses and training status. Furthermore, caffeine's legal status and potential interactions with other substances, such as alcohol and medications, must be considered in competitive settings.
Label-free (fluorescence-free) sensing of a single DNA molecule on DNA origami using a plasmon-enhanced WGM sensor
Authors: Ghamari Shahin , Chiarelli Germán , Kołątaj Karol , Subramanian Sivaraman , Acuna Guillermo P. , Vollmer Frank 
Published: January 2025

Abstract
The integration of DNA origami structures with opto-plasmonic whispering gallery mode (WGM) sensors offers a significant advancement in label-free biosensing, overcoming the limitations of traditional fluorescence-based techniques, and providing enhanced sensitivity and specificity for detecting DNA hybridization events. In this study, DNA origami acts as a scaffold for the precise assembly of plasmonic dimers, composed of gold nanorods (AuNRs), which amplify detection sensitivity by generating strong near-field enhancements in the nanogap between the nanorods. By leveraging the strong electromagnetic fields generated within the nanogap of the plasmonic dimer, this platform enables the detection of transient hybridization events between DNA docking strands and freely diffusing complementary sequences. Our findings demonstrate that the salt concentration critically influences DNA hybridization kinetics. Higher ionic strengths reduce electrostatic repulsion between negatively charged DNA strands, thereby stabilizing duplex formation and prolonging interaction times. These effects are most pronounced at salt concentrations around 300–500 mM, where optimal conditions for duplex stability and reduced dissociation rates are achieved. By thoroughly investigating the hybridization kinetics under varying environmental conditions, this study contributes to a deeper understanding of DNA interactions and offers a robust tool for single-molecule detection with real-time capabilities.
Do Prosecutors Have The Authority To Realize The Restorative Justice? An Indonesian Case
Authors: Sasongko Andy , Abdul Madjid  , Yuliati  , Fachrizal Afandi  
Published: January 2025

This article explores the role of a prosecutor in realizing restorative justice in Indonesia. This research employs a socio-legal method, focusing on how legal certainty, legal order, justice, and truth can be achieved by upholding human values, religious norms, politeness, and decency. The Attorney General of the Republic of Indonesia has established, among others, the prosecutorial function and authority to promote restorative justice in terminating prosecutions in Indonesia based on Prosecutor's Regulation of Indonesia (PERJA RI) Number 15 of 2020 concerning Termination of Prosecutions Based on Restorative Justice. With the amendment of PERJA RI, it is hoped that the public prosecutor in handling criminal cases will act more humanely and conscientiously, prioritizing restorative justice, which aims at restoration to protect the lives of victims and people who commit criminal acts on the grounds of humanity and justice in society instead of focusing on retaliation against perpetrators. As the state institution responsible for prosecutions, the prosecutor's office strives to uphold legal certainty, truth, and justice in line with legal principles while respecting humanity, morality, decency, and religious values.
Antibacterial Activity of Ethyl Acetate Extract of Mango Bud (Mangifera indica L. var. Arum Manis) Against Multidrug-Resistant Bacteria
Authors: Mulangsri Dewi Andini Kunti , Nisa Maurizka Chairun , Sugihartanti Diana Nuraini , Hidayah Arini Ulfa 
Published: January 2025

Ethyl acetate extracts of Mangifera indica leaves had chemical constituents such as saponins, alkaloids, phenols, tannins, flavonoids and diterpenes. Purified extract of Mangifera indica leaves had antibacterial activity against S. aureus and E. coli. This research aimed to know the antibacterial activity of mango bud (Mangifera indica L. var Arum Manis) against S. aureus, E. coli, P. aeruginosa and their multidrug resistant spesies. Arum manis mango bud simplicia powder was extracted by maceration method used ethyl acetate solvent. This extract tested to flavonoids and alkaloids by qualitative methods. Antibacterial activity used disc diffusion method and the concentration of this extract such as 10, 20, 30, 40 and 50%. Data of antibacterial activity was analyzed by descriptively. Arum manis mango bud extract had antibacterial activity against all of tested bacteria with diameter of zone of inhibition at 6.76 – 12.20 mm. The arum manis mango bud extract contained flavonoids and alkaloids.
Molecular epidemiology of human papillomavirus variants in cervical cancer in India
Authors: Sharma Nita , Changotra Harish , Kaur Manpreet 
Published: January 2025

Background & objectives
Cervical cancer (CC) has been documented as the fourth most common cancer worldwide. Persistent infections with high-risk human papillomavirus (hr-HPV) have been suggested in the development of CC. Although prophylactic vaccines are available for the prevention of prevalent hr-HPV types, intra-type variations exist within a particular HPV type that has varying oncogenic potential as well as the mechanism of pathogenicity and varying neutralization by antibodies. Therefore, we carried out a systematic review to determine the distribution of HPV intra-typic variations in different geographical locations of India and their reported implications.

Methods
Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were followed to retrieve relevant articles from the standard databases using appropriate keywords. Consequently, 17 articles were included in the current review after screening based on inclusion and exclusion criteria.

Results
The majority of articles included in this review reported variations within the HPV16 E6 gene, followed by the L1 and E7 genes. Analysis of available data indicated the differential regional distribution of some variations. These variations have also been reported to impact the biological functions of various viral proteins.

Interpretation & conclusions
The distribution of lineages varied with the different genomic regions sequenced. Additionally, there were certain unique and common variations in the HPV genome with respect to geographical regions. Hence, we suggest the identification of region-specific variations for the development of diagnostic and prognostic interventions.
Cognitive Insights from Emotional Intelligence: A Systematic Review of EI Models in Educational Achievement
Authors: Gkintoni Evgenia , Dimakos Ioannis , Nikolaou Georgios 
Published: January 2025

Objectives: This study aims to investigate the relationship between Emotional Intelligence (EI) and academic achievement within educational settings. It seeks to determine how different EI models—specifically, Ability EI and Trait EI—impact students' academic performance, behavior, engagement, and motivation. The goal is to provide insights that can guide the integration of EI into educational practices to foster a more supportive and effective learning environment. Methods/Analysis: The study is based on a systematic review of sixty-four (64) peer-reviewed studies published between 2016 and 2023. These studies include randomized controlled trials (RCTs), longitudinal studies, and meta-analyses. The selected studies were analyzed to explore the effects of EI on various academic outcomes, including performance, behavioral engagement, and motivation. Findings: The analysis reveals that both Ability EI and Trait EI are positively associated with academic success. These models of EI appear to contribute significantly to the development of key skills such as emotional control, empathy, and problem-solving, which in turn support effective classroom management and academic achievement. The findings suggest that incorporating EI into educational curricula can lead to improved communication, better problem-solving abilities, and enhanced relationships between students and faculty. These improvements can create a more conducive learning environment and enhance overall academic outcomes. Novelty/Improvement: This study adds to the existing literature by offering a comprehensive review of recent studies that examine the role of EI in academic settings. It highlights the importance of implementing EI-focused interventions and curricula in schools, emphasizing the practical implications for educators and policymakers. Doi: 10.28991/ESJ-2024-SIED1-016 Full Text: PDF
La identificación de los conocimientos previos en la estructura cognitiva en estudiantes de primer ingreso a la universidad
Authors: Heredia Murillo Jorge Alberto , Benavides Martínez Benigno , Cuevas Gutiérrez Ana Irene 
Published: January 2025

La presente investigación busca identificar los conocimientos previos que poseen los estudiantes de primer ingreso en la universidad, partiendo del trabajo realizado por Hailikari & Nevgi (2010), sobre los tipos y niveles de conocimiento previo que existen. Se utilizo una metodología cualitativa a través de la técnica del focus group el cual se aplicó a un grupo de estudiantes de primer semestre compuesto de 5 hombre y 5 mujeres. Como resultado se identificaron distintos tipos de conocimientos previos: de hechos, de significados, de integración y aplicación del conocimiento, estos se ubican como conocimientos declarativos y procedimentales, estos últimos se relacionaron con las estrategias metacognitivas. La finalidad del estudio fue reconocer los conocimientos previos que han contribuido para que los estudiantes puedan establecer un puente entre el grado académico anterior, generar nuevos conocimientos y tener confianza para transitar en esta nueva etapa académica.
Pengembangan Web Edukasi Kompetensi Membaca Berbasis Ensiklopedia bagi Mahasiswa BIPA Tingkat Madya
Authors: Hermanto Hermanto , Agustin Thesia Anggraini , Himawan Riswanda 
Published: January 2025

Penelitian ini dilatarbelakangi dengan kurangnya bahan ajar digital yang kreatif pada proses belajar mengajar terutama pada materi pariwisata. Berdampak pada kurangnya motivasi pemelajar dalam melaksanakan pembelajaran. Untuk mengatasi persoalan tersebut perlu pengembangan bahan ajar digital. Salah satunya dengan mengembangkan web edukasi berbasis ensiklopedia. Penelitian ini merupakan penelitian pengembangan dengan model ADDIE. Selaras dengan jenisnya, penelitian ini bertujuan untuk mengembangkan web edukasi membaca bagi mahasiswa BIPA tingkat madya. Setelah dilakukan pengembangan produk. Tahapan yang digunakan untuk mengetahui kelayakan web edukasi yaitu melakukan uji kelayakan kepada ahli dan respons mahasiswa. Observasi, wawancara, dan angket digunakan sebagai teknik pengumpulan data. Deskriptif kuantitatif merupakan analisis datanya. Penelitian ini dilakukan pada pemelajar BIPA tingkat madya Universitas Ahmad Dahlan. Hasil penelitian ini adalah sebagai berikut: (1) hasil analisis kebutuhan menujukkan bahwa saat ini diperlukan adanya pengembangan web pada kelas membaca mahasiswa BIPA; (2) Hasil kelayakan ahli materi memperoleh skor 84,12% dengan kriteria “baik sekali”. Ahli media 90% dengan kriteria “baik sekali”. Hasil penelitian dari validasi ahli pengajaran tahap pertama 72,58% dengan kriteria “baik”. Hasil penelitian dari validasi ahli pengajaran tahap kedua 86,7% dengan kategori “baik sekali”. Hasil uji coba kelompok kecil 88,75% dengan kategori “baik sekali”. Dari hasil tersebut, dapat disimpulkan bahwa bahwa web edukasi layak untuk digunakan dalam proses pembelajaran membaca bagi mahasiswa BIPA tingkat madya.Kata Kunci: Pengembangan; Bahan Ajar; WEB; BIPA
Menelusuri Tataran Kejadian dan Riwayat dalam Novel 1Q84 Karangan Haruki Murakami: Kajian Naratologi
Authors: Arianto Anggiarini , Pribadi Rendy 
Published: January 2025

Salah satu cabang ilmu linguistik yang membicarakan permasalahan alur dalam bercerita, yakni naratologi, belum banyak diperbincangkan dan dikaji dalam dunia akademik. Kajian dalam bercerita ini khususnya naratologi belum memiliki model yang baik dalam mengkaji karya fiksi cerpen terutama dalam karya fiksi berbahasa Jepang. Penelitian ini bertujuan untuk menawarkan dan menegosiasikan kemampuan mengkaji karya fiksi menggunakan analisis naratologi melalui penerapan model naratologi tataran kejadian dan riwayat. Model Rimmon-Kenan, Shlomith inilah yang digunakan untuk menganalisis kejadian dan riwayat dari setiap karya fiksi. Penelitian ini merupakan penelitian analisis isi yang menganalisis dan menginterpretasi novel berjudul IQ84. Jenis penelitian ini adalah kualitatif. Teori yang digunakan pada penelitian ini adalah teori kejadian dan riwayat, yang ditawarkan oleh Rimmon-Kenan dan Shlomith. Hasil penelitian dalam tataran kejadian menawarkan hubungan kausal dalam sebuah cerita yang berfungsi menghubungkan keadaan seimbang awal, ketidakseimbangan, dan keseimbangan baru. Tataran riwayat menunjukkan dampak ketidakseimbangan sebagai rumusan umum yang bisa digunakan dalam menentukan titik konflik yang terjadi dalam sebuah cerita, seperti penggunaan tataran kejadian dan riwayat yang bertemu pada suatu pembahasan, yakni aliran Sakigeki dan tataran riwayat dalam novel ini menunjukkan keadaan seimbang baru dari masing-masing tokohya, yakni Aomame dan Tango. Implikasi pada pengajaran sastra sebagai tawaran dalam menentukan bentuk kaidah progresif atau flashback sehingga dapat digunakan dalam penentuan ideologi. Kata Kunci: Model Tataran Riwayat; Naratologi; Novel.
Kekuasaan Pemikiran pada Novel Yang Telah Lama Pergi Karya Tere Liye
Authors: Arianti Linda , Affandy Ali Nuke , Kartika Pheni Cahya 
Published: January 2025

Hidup manusia itu menguasai. Kekuasaan begitu menarik minat hingga menarik manusia untuk mendekatinya. Sebagian manusia merasa senang karena mampu mengendalikan manusia lain dan membuat manusia lain mengikuti keputusannya. Kekuasaan memiliki arti sebagai pengaruh atau kekuatan atas pemikiran yang digunakan untuk memengaruhi individu atau kelompok agar menjadikan mereka patuh dengan apa yang diperintahkan. Penelitian ini bertujuan untuk mendeskripsikan kekuasaan yang didasari oleh sebuah pemikiran dimana ada kekuasaan yang didasari oleh sebuah pemikiran dan menghasilkan taktik untuk meruntuhkan kerajaan Sriwijaya. Penelitian ini menggunakan teori kekuasaan pemikiran perspektif Michel Foucault. Penelitian ini dilatarbelakangi oleh adanya pemikiran-pemikiran yang berbeda oleh ke-8 tokoh yang bergabung untuk menyelesaikan satu misi besar bersama para perompak pada novel Yang Telah Lama Pergi karya Tere Liye. Metode yang digunakan dalam penelitian ini yaitu deskriptif kualitatif. Teknik pengumpulan data menggunakan studi pustaka yang merupakan proses pengumpulan data dengan cara membaca referensi terdahulu dan teknik pengumpulan data yang digunakan pada penelitian ini melalui beberapa tahapan yaitu (1) membaca, (2) menandai, dan (3) menganalisis. Hasil penelitian yang ditemukan adalah (1) setiap tokoh pada novel Yang Telah Lama Pergi memiliki pemikiran yang berbeda dan berpengaruh dalam sebuah kekuasaan (2) Kekuasaan pada novel Yang Telah Lama Pergi berjalan dengan pikiran atau pengetahuan yang menghasilkan taktik yang dijalankan untuk meruntuhkan Kerajaan Sriwijaya.Kata Kunci: Kekuasaan; Pemikiran; Michel Foucault