bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of peripheral active warming and passive insulation on core body temperature during feline ovariohysterectomy: a multi-arm randomized clinical trial
Authors: Kreisler Rachael E , MacDonald Lauren J , Mensing Rachel N , Hoffmann Emma R , Keary Carissa G , Padilla Kayla N , Norris Jeffrey W 
Published: March 2023

Objectives Hypothermia is a common complication of anesthesia, particularly in cats. Some veterinarians insulate the extremities of cats as a preventive measure, and there is evidence that heating the extremities of dogs decreases the rate of heat loss from the core. This study investigated whether active warming or passive insulation of the extremities of cats resulted in a slower decrease in rectal temperature during anesthesia. Methods Female cats were assigned via block randomization to passive (cotton toddler socks), active (heated toddler socks) or control group (uncovered extremities). Rectal temperature was monitored every 5 mins from induction through return to trap/carrier (final temperature). Multivariable linear regression models were used to compare temperature (rate change and final) between groups. Results There were 164 cats with 1757 temperature readings. Mean total duration of anesthesia was 53 ± 13 mins. The temperature of all groups decreased linearly over time (all P <0.0001), with the rates of temperature decrease being −0.039°F/min (95% confidence interval [CI] −0.043 to −0.035)/−0.022°C (95% CI −0.024 to −0.019), −0.039°F/min (95% CI −0.042 to −0.035)/−0.022°C (95% CI −0.023 to −0.019) and −0.029°F/min (95% CI −0.032 to −0.025)/−0.016°C (95% CI −0.018 to −0.014) for the control, passive and active groups, respectively. The control, passive and active groups had median final temperatures of 98.4°F (interquartile range [IQR] 97.6−99.4)/36.9°C (IQR 36.4−37.4), 98.0°F (IQR 97.2–98.7)/36.7°C (IQR 36.2–37.1) and 99.1°F (IQR 97.7–100.0)/37.3°C (IQR 36.5–37.8), respectively. After controlling for weight, postinduction temperature and duration of anesthesia, and as compared with controls, the final temperature of the active group was predicted to be 0.54°F (95% CI 0.03–1.01)/0.3°C (95% CI 0.02–0.56) greater ( P = 0.023), while the passive group was not significantly different ( P = 0.130). Conclusions and relevance The rate of rectal temperature decrease was significantly slower for the active group compared with the other groups. Although the cumulative difference in final temperature reading was modest, superior materials might enhance performance. Cotton toddler socks alone did not slow the rate of temperature decrease.
Developing Awareness of Green Human Resource Development Practices in the Hotel Industry
Authors: Osolase Ehikioya Hilary , Rasdi Roziah Mohd , Mansor Zuraina Dato’ 
Published: March 2023

The Problem The hotel industry is a major contributor to the depletion of natural resources (e.g., water and energy) and other practices (e.g., waste management and pollution) that jeopardizes environmental sustainability. The expertise of human resource development (HRD) practitioners is needed to develop the knowledge and skills of industry practitioners towards the development of pro-green knowledge and competencies for automation of workflows for environmental sustainability. The Solution Green human resource development is suggested as a paradigm shift from traditional approaches of HRD to bring awareness of ways that HRD expertise can be applied to green practices. By integrating the expertise, knowledge, and competencies of HRD practitioners with industry practitioners, the hotel industry has the potential to be transformed into a sector with ecofriendly and pro-environmental culture. The Stakeholders Human resource development researchers and practitioners; hotel industry workforce (practitioners, organizational leaders, and all sectors of the workforce).
The results of thrombectomy from the arteries of the lower extremities in patients infected with SARS-CoV-2 Omicron variant with different severity of respiratory failure
Authors: Kazantsev Anton N , Zharova Alina S , Shmatov Dmitriy V , Zakeryaev Aslan B , Lider Roman Yu , Kazantseva Elizaveta G , Bagdavadze Goderzi S. , Korotkikh Alexander V , Lutsenko Victor A , Sultanov Roman V , Lebedev Oleg V , Sirotkin Alexey A , Snopova Elena V , Palagin Petr D 
Published: March 2023

Goal Analysis of the results of thrombectomy from the arteries of the lower extremities in patients with COVID-19 against the background of different severity of respiratory failure. Materials and Methods This retrospective, cohort, comparative study for the period from 05/01/2022 to 20/07/2022 included 305 patients with acute thrombosis of the arteries of the lower extremities against the background of the course of COVID-19 (SARS-CoV-2 Omicron variant). Depending on the type of oxygen support, 3 groups of patients were formed: group 1 ( n = 168) – oxygen insufflation through nasal cannulas; group 2 ( n = 92) – non-invasive lung ventilation; and group 3 ( n = 45) – artificial lung ventilation. Results Myocardial infarction and ischemic stroke were not detected in the total sample. The highest number of deaths (group 1: 5.3%, n = 9; group 2: 72.8%, n = 67; group 3: 100%, n = 45; p < 0.0001), rethrombosis (group 1 : 18.4%, n = 31; group 2: 69.5%, n = 64; group 3: 91.1%, n = 41; p < 0.0001), and limb amputations (group 1: 9.5%, n = 16; group 2: 56.5%, n = 52; group 3: 91.1%, n = 41; p < 0.0001) was recorded in group 3 (ventilated) patients. Conclusion In patients infected with COVID-19 and on artificial lung ventilation, a more aggressive course of the disease is noted, expressed in an increase in laboratory parameters (C-reactive protein, ferritin, interleukin-6, and D-dimer) of the degree of pneumonia (CT-4 in overwhelming number) and localization of thrombosis of the arteries of the lower extremities, mainly in the tibial arteries.
Adherence of healthcare workers to COVID-19 infection prevention practices and its relationship with SARS-CoV-2 seropositivity
Authors: El-Ghitany Engy Mohamed , Ashour Ayat , Elmorshedy Hala , Farghaly Azza Galal , Hashish Mona H. , Omran Eman A. 
Published: March 2023

Background Infection prevention and control (IPC) practices against COVID-19 should be adopted by healthcare workers (HCWs) at their workplaces to protect themselves, their patients, and their families from infection. Purpose This study aimed to describe the relationship between the healthcare-related COVID-19 infection prevention measures adopted by HCWs and their SARS-CoV-2 seropositivity. Research Design This cross-sectional study was conducted during the second and third COVID-19 waves in Egypt. Study Sample The study included 416 unvaccinated HCWs from 39 hospitals in Egypt. Data Collection Sociodemographic data, as well as COVID-19 IPC measures done at work, and protective measures performed by their healthcare facilities were collected. SARS-CoV-2 spike protein antibodies were measured by ELISA. Results 58.2% of participants were seropositive for SARS-CoV-2. Among the previously undiagnosed HCWs, 125/271 (46.1%) were seropositive. Predictors of seropositivity were rural residence (aOR = 5.096; 95% CI: 1.583–16.403, p = 0.006), previous COVID-19 infection (aOR = 4.848, 95% CI: 2.933–8.015, p = 0.000), and examining 10–20 suspected COVID-19 patients daily (aOR = 2.329; 95% CI: 1.331–4.077, p = 0.003. Reporting low satisfaction (25–50%) with infection control implementation, working more than 40 h per week, reporting to “sometimes abiding by hand hygiene” compared to those who reported to “always” adhere to hand hygiene and shorter duration of hand washing (<20 s) were associated with significantly higher odds of seropositivity. Conclusions Poor infection control measures and the high workload of HCWs (longer working hours and examining more patients) were modifiable risk factors for SARS-CoV-2 seropositivity among HCWs. Hand hygiene was better among HCWs working in urban versus rural areas.
Zincorietveldite, Zn(UO2)(SO4)2(H2O)5, the zinc analogue of rietveldite from the Blue Lizard mine, San Juan County, Utah, USA
Authors: Kampf Anthony R. , Olds Travis A. , Plášil Jakub , Marty Joe 
Published: March 2023

AbstractThe new mineral zincorietveldite (IMA2022-070), Zn(UO2)(SO4)2(H2O)5, was found in the Blue Lizard mine, San Juan County, Utah, USA, where it occurs as yellow to orange–yellow blades in a secondary assemblage with bobcookite, coquimbite, halotrichite, libbyite, metavoltine, rhomboclase, römerite, tamarugite and voltaite. The streak is very pale yellow. Crystals are transparent with vitreous lustre. The tenacity is brittle, the Mohs hardness is ~2½ and the fracture is curved. Cleavage is excellent on {010}, good on {100} and fair on {001}. The mineral is easily soluble in H2O and has a calculated density of 3.376 g⋅cm–3. The mineral is optically biaxial (+) with α = 1.568(2), β = 1.577(2) and γ = 1.595(2); 2V = 70(1)°. Electron microprobe analyses provided (Zn0.720Mg0.109Fe0.091Mn0.046Co0.035)Σ1.00(UO2)(SO4)2(H2O)5. Zincorietveldite is orthorhombic, Pmn21, a = 12.8712(9), b = 8.3148(4), c = 11.2959(4) Å, V = 1208.90(11) Å3 and Z = 4. Zincorietveldite is the Zn analogue of rietveldite. The structural unit is a uranyl-sulfate chain that is also found in the structures of bobcookite, oldsite, oppenheimerite and svornostite.
Crystal-chemical characterisation and spectroscopy of fluorcarletonite and carletonite
Authors: Kaneva Ekaterina , Bogdanov Alexander , Radomskaya Tatiana , Belozerova Olga , Shendrik Roman 
Published: March 2023

AbstractThe minerals of carletonite group, fluorcarletonite, KNa4Ca4[Si8O18](CO3)4(F,OH)·H2O and carletonite, Na4Ca4[Si8O18](CO3)4(OH,F)·H2O, were investigated using a multi-method approach. A detailed comparative chemical study of the minerals was carried out using electron probe microanalysis and Fourier transform infrared spectroscopy. Using X-ray techniques and the results obtained, geometrical and distortion characteristics of the mineral structures are calculated and the successful crystal-structure refinement of these two natural compounds are given. Using spectroscopic and luminescence methods and ab initio calculations, it is shown that hole defects (CO3)•– are responsible for the colouration of the samples studied. Luminescence due to 5d–4f transition in Ce3+ ions is observed in both investigated compounds. Moreover, luminescence attributed to intrinsic luminescence, corresponding to the decay of electronic excitations of (CO3)2– complexes in the carletonite sample, is registered for the first time in phyllosilicates. An analysis of the optical absorption spectra and g-tensor values suggests that (CO3)•– defects in the crystal structure are localised in the C1 positions. Identification of these specific properties for these sheet silicates, with a two-dimensional infinite tetrahedral polymerisation, indicates that carletonites could be prospective materials for novel phosphors and luminophores.
Lung cancer screening in rural primary care practices in Colorado: time for a more team-based approach?
Authors: Gomes Rebekah , Nederveld Andrea , Glasgow Russell E. , Studts Jamie L. , Holtrop Jodi Summers 
Published: March 2023

AbstractBackgroundDespite lung cancer being a leading cause of death in the United States and lung cancer screening (LCS) being a recommended service, many patients eligible for screening do not receive it. Research is needed to understand the challenges with implementing LCS in different settings. This study investigated multiple practice members and patient perspectives impacting rural primary care practices related to LCS uptake by eligible patients.MethodsThis qualitative study involved primary care practice members in multiple roles (cliniciansn = 9, clinical staffn = 12 and administratorsn = 5) and their patients (n = 19) from 9 practices including federally qualified and rural health centers (n = 3), health system owned (n = 4) and private practices (n = 2). Interviews were conducted regarding the importance of and ability to complete the steps that may result in a patient receiving LCS. Data were analyzed using a thematic analysis with immersion crystallization then organized using the RE-AIM implementation science framework to illuminate and organize implementation issues.ResultsAlthough all groups endorsed the importance of LCS, all also struggled with implementation challenges. Since assessing smoking history is part of the process to identify eligibility for LCS, we asked about these processes. We found that smoking assessment and assistance (including referral to services) were routine in the practices, but other steps in the LCS portion of determining eligibility and offering LCS were not. Lack of knowledge about screening and coverage, patient stigma, and resistance and practical considerations such as distance to LCS testing facilities complicated completion of LCS compared to screening for other types of cancer.ConclusionsLimited uptake of LCS results from a range of multiple interacting factors that cumulatively affect consistency and quality of implementation at the practice level. Future research should consider team-based approaches to conduct of LCS eligibility and shared decision making.
Development and validation of a clinical nomogram for differentiating hemorrhagic and ischemic stroke prehospital
Authors: Ye Sheng , Pan Huiqing , Li Weijia , Wang Jinqiang , Zhang Hailong 
Published: March 2023

Abstract
Objectives
The early detection and identification of stroke are essential to the prognosis of patients with suspected stroke symptoms out-of-hospital. We aimed to develop a risk prediction model based on the FAST score to identify the different types of strokes early for emergency medical services (EMS).

Methods
This retrospective observational study enrolled 394 stroke patients at a single center from January 2020 to December 2021. Demographic data, clinical characteristics, and stroke risk factors with patients were collected from the EMS record database. Univariate and multivariate logistic regression analysis was used to identify the independent risk predictors. The nomogram was developed based on the independent predictors, in which the discriminative value and calibration of the nomogram were verified by the receiver operator characteristic (ROC) curve and calibration plots.

Results
A total of 31.90% (88/276) of patients were diagnosed with hemorrhagic stroke in the training set, while 36.40% (43/118) in the validation set. The nomogram was developed based on the multivariate analysis, including age, systolic blood pressure, hypertension, vomiting, arm weakness, and slurred speech. The area under the curve (AUC) of the ROC with nomogram was 0.796 (95% CI: 0.740–0.852, P < 0.001) and 0.808 (95% CI:0.728–0.887, P < 0.001) in the training set and validation set, respectively. In addition, the AUC with the nomogram was superior to the FAST score in both two sets. The calibration curve showed a good agreement with the nomogram and the decision curves analysis also demonstrated that the nomogram had a wider range of threshold probabilities than the FAST score in the prediction risk of hemorrhagic stroke.

Conclusions
This novel noninvasive clinical nomogram shows a good performance in differentiating hemorrhagic and ischemic stroke for EMS staff prehospital. Moreover, all of the variables of nomogram are acquired in clinical practice easily and inexpensively out-of-hospital.
Clinical characteristics and therapeutic effects of checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer
Authors: Pang Li , Xie Mei , Ma Xidong , Huang Aiben , Song Jialin , Yao Jie , Deng Hui , Zhang Duchao , Zang Xuelei , Ren Fangping , Gao Jie , Wu Chongchong , Wang Yuanyong , Zhang Xin , Bao Xinyu , Pan Lei , Xue Xinying 
Published: March 2023

AbstractBackgroundWith the application of immune checkpoint inhibitors (ICIs) in cancer treatment, more and more attention has been paid to checkpoint inhibitor-related pneumonitis (CIP), which requires a better understanding of its clinical characteristics and therapeutic effects.MethodsThe clinical and imaging data of 704 patients with non-small cell lung cancer (NSCLC) who received immunotherapy were analyzed retrospectively; the clinical characteristics of CIP were summarized, and the therapeutic regimens and effects of the patients were summarized.Results36 CIP patients were included in the research. The most common clinical symptoms were cough, shortness of breath and fever. The CT manifestations were summarized as follows: Organizing pneumonia (OP) in 14 cases (38.9%), nonspecific interstitial pneumonia (NSIP) in 14 cases (38.9%), hypersensitiviy pneumonitis(HP) in 2 cases (6.3%), diffuse alveolar damage in 1 case (3.1%) and atypical imaging manifestations in 5 cases (13.9%). 35 cases received glucocorticoid therapy, 6 patients were treated with gamma globulin and 1 patient was treated with tocilizumab. There were no deaths in CIP G1-2 patients and 7 deaths occured in CIP G3-4 patients. 4 patients were treated again with ICIs.ConclusionWe found that glucocorticoid 1–2 mg/kg was effective for most patients with moderate to severe CIP, and a few patients with hormone insensitivity needed early immunosuppressive therapy. A few patients can be rechallenged with ICIs, but CIP recurrence needs to be closely monitored.
A text-mining study on emotional cognition, understanding, and preventative behaviors during the COVID-19 pandemic
Authors: Lim Eunjung , Shin Jieun , Park Seyeon 
Published: March 2023

Abstract
Background
This study aimed to look at emotions perceived about the attributes, prevention, diagnosis, and treatment of infectious diseases related to coronavirus disease (COVID-19) that were widespread across the world and identify their relevance to knowledge about infectious diseases and preventative behaviors.

Methods
Texts to measure emotional cognition were selected through a pre-test, and 282 people were chosen as participants based on the survey conducted for 20 days from August 19 to August 29, 2020, created with Google Forms. IBM SPSS Statistics 25.0 was used for the primary analysis, and the SNA package in R (version 4.0.2) was utilized to conduct the network analysis.

Results
It was found that universal negative emotions such as feeling “anxious” (65.5%), “afraid” (46.1%), and “scared” (32.7%) commonly appeared among most people. Also, they were found to be feeling both positive (“caring” [42.3%] and “strict” [28.2%]) and negative (“frustrating” [39.1%] and “isolated” [31.0%]) emotions about efforts to prevent and curb the spread of COVID-19. In terms of emotional cognition for the diagnosis and treatment of such diseases, “reliable” (43.3%) took the biggest ratio among the replies. The level of understanding about infectious diseases showed differences in emotional cognition, thereby affecting people’s emotions. However, no differences were found in the practice of preventative behaviors.

Conclusions
Emotions associated with cognition in the context of pandemic infectious diseases have been found to be mixed. Furthermore, it can be seen that feelings vary depending on the degree of understanding of the infectious disease.
The experience of diabetic retinopathy patients during hospital-to-home full-cycle care: A qualitative study
Authors: Zhang Mengyue , Zhang ChunHua , Chen Chen , Liu Linjie , Liang Youping , Hong YiRong , Chen Yanyan , Shi Yinghui 
Published: March 2023

Abstract
Background
Diabetic retinopathy (DR) is one of the major blinding eye diseases worldwide. Psychological, emotional and social problems of DR patients are prominent. The aim of this study is to explore the experiences of patients with different phases of DR from hospital to home based on the “Timing It Right” framework, and to provide a reference for formulating corresponding intervention strategies.

Methods
The phenomenological method and semi-structured interviews were used in this study. A total of 40 patients with DR in different phases were recruited from a tertiary eye hospital between April and August 2022. Colaizzi’s analysis method was used to analyse the interview data.

Results
Based on the “Timing It Right” framework, different experiences in five phases of DR before and after Pars Plana Vitrectomy (PPV) were extracted. The patients experienced complicated emotional reactions and inadequate coping skills during the pre-surgery phase, increased uncertainty during the post-surgery phase, insufficient confidence and the decision to change during the discharge preparation phase, eagerness for professional support and moving forward in exploration during the discharge adjustment phase, and courageous acceptance and positive integration during the discharge adaptation phase.

Conclusion
The experiences of DR patients with vitrectomy in different phases of disease are ever-changing, and medical staff should provide personalized support and guidance to help DR patients get through the hard times smoothly and enhance the quality of hospital-family holistic care.
Purification and characterization of aspartic protease from Aspergillus niger and its efficient hydrolysis applications in soy protein degradation
Authors: Wei Mengyuan , Chen Pengcheng , Zheng Pu , Tao Xiumei , Yu Xiaowei , Wu Dan 
Published: March 2023

Abstract
Background
Adding acid protease to feed can enhance protein digestibility, boost feed utilization, and stimulate the growth of animals in breading industry. In order to obtain an acid protease with high hydrolysis efficiency to plant protein, in this study, an aspartic protease from Aspergillus niger was heterologous expressed in Pichia pastoris (P. pastoris). The enzymatic properties and application in soybean protein degradation were also studied.

Results
In our investigation, the high aspartic protease (Apa1) activity level of 1500 U/mL was achieved in 3 L bioreactor. After dialysis and anion exchange chromatography, the total enzyme activity and specific enzyme activity were 9412 U and 4852 U/mg, respectively. The molecular weight of the purified protease was 50 kDa, while the optimal pH and temperature were 3.0 and 50 °C, respectively. It was stable at pH 2.0–5.0 and 30–60 °C. Apa1 was used to hydrolyze soybean isolate protein (SPI) at 40 °C and pH 3.0, and a high hydrolysis degree (DH) of 61.65% was achieved. In addition, the molecular weight distribution of SPI hydrolysis products was studied, the result showed that the hydrolysis products were primarily oligopeptides with molecular weights of 189 Da or below.

Conclusions
In this study, Apa1 was successfully expressed in P. pastoris and high expression level was obtained. In addition, the highest protein hydrolysis rate to SPI degradation so far was achieved. The acid protease in this study provides a new protease that is suitable for the feed industry, which will be very helpful to improve the feed utilization and promote the development of the breeding industry.