bluuebunny/crossref_metadata_2025_split huggingface dataset:
The fundamentals of the book studies (The review of the book “Neurobibliology: The first effort of the cognitive study” by V. P. Leonov)
Authors: Stolyarov Yu. N. 
Published: September 2023

The book [in Russian] comprises three chapters, i. e. “The book as a human innate program”, “The bibliology in search of the meanings: The book is an outer cognitome?”, “The bibliology and music as an outer cognitome and form of knowledge”, “On the reading neurobiology and “brain book”, “Neurphilosophy and neurobibliology: The problems at the interface of disciplines”, “On the interdisciplinarity of bibliology: From Bibliologos to Neurobibliology”, and “Neurbibliology as the interdisciplinary studies of the book and cognitive processes”.The reviewer dissects and analyzes the key provisions of the book. The assumption that “the book is the human innate program” contradicts to the speech evolutionary descent theory and to the practice. The documentology also answers to the question surprisingly mysterious to the book author (“what are the origins of the writing?”) – the sound is a sign and “represents” the thought. It is impossible to preserve the initial meaning for the long time so the appropriate equivalent had to be found in the form of the letters as the transformed sound signs, or the code.Further, V. Leonov develops the concept of the book as an outer cognitome, i. e. the element of integrated biomedical, technological, and existential – brain cognitive power which makes him to view the bibliology on the conjunction of neurosciences and the humanities. The theory of cognitive systems has to become the methodological foundation of the bibliology and bibliography, and the Russian Academy of Sciences needs an interdisciplinary analytic center for studies of the book phenomenon. The author suggests the term “bibliology of neurosciences” for the new discipline. Besides, he suggests that a new interdisciplinary science of cognitology has to integrate psychology, computer science, linguistics, anthropology, neuroscience, philosophy, pedagogy, bibliology, and bibliography in the aspect of knowledge. The cognitome is the innate cognitome while the book is an outer cognitome. This interpretation coincides with that of K. Popper’s three worlds, one of which is the world of “products of thought”, the objects in their own right. The reference to this concept would significantly strengthen Leonov’s hand.
Pre-scaling up of ground nut varieties in selected districts of West and Kellem Wollega zones, Ethiopia
Authors: Hika Tasfa  , Damaksa Umar  
Published: September 2023

The study was conducted in Dale sadi, Dale wabera and Sayo districts of Kellem wollega Zone and Gimbi districts of west Wollega zone for two consecutive years of production(2016/17 and 2017/18 G.C ) on farmers’ field. The objective of the study was to pre-scale up and popularize the best-performing and preferred groundnut variety in the study area. The study addressed a total of 90 farmers in the two years of the project span. From a total of 90 farmers, male represents 73 and female 17. During farmers’ selection process, both female and male farmers were incorporated so as to avoid gender bias. Training was given to the selected farmers, development agents and district experts about improved groundnut technologies production and management. Full packages of the technologies were provided. Variety Manipinter was planted on plot area of 0.25ha on respective farmers’ field in the study area. The recommended rate of NPS 100kg/ha and Row planting method with the spacing of 60cm between rows and 10cm between plants were used respectively. To enhance farmer’s knowledge on Groundnut training was given for target community on agronomic practice of Groundnut. During training a total of 117 target communities were participated on training out of which 84 were male and 33 were male. An average production of 14.935 qt/ha and a total of 336 quintal of groundnut yield was harvested during project life span. Finally, farmers feedback concerning technology was collected and incorporated, accordingly the farmers feel as the Manipinter have relatively high yield, good seed quality (Grain size, color), disease tolerant than previously used varieties. Generally, since it is impossible to address all farmers only by the effort of the research center, district agriculture and natural resource bureau in collaboration with zonal agricultural and natural resource office and input supplying NGO’s should hold the turn to scale up the technology in wider scale.
Res. Agric. Livest. Fish. Vol. 10, No. 2, August 2023: 147-153
Tratamento de queimaduras de 2º grau com Ácido Hialurônico 0,2%: Revisão integrativa da literatura
Authors: Silva Arthur Carmo , Cintra Bruno Barreto , Maia Júlia Beatriz Barros Lins , Couto Flávia Dantas Santos do , Oliveira Clara Vitória Braz Lima de 
Published: September 2023

As queimaduras de segundo grau afetam a camada externa da pele, conhecida como epiderme, e a camada subjacente, chamada de derme. Elas podem ser causadas por fontes de calor, como chamas, líquidos quentes ou contato prolongado com superfícies aquecidas. O tratamento eficaz das queimaduras de segundo grau é importante para promover a cicatrização adequada, prevenir infecções e minimizar o impacto físico e emocional nos pacientes. O ácido hialurônico a 0,2% tem despertado interesse no tratamento de queimaduras de segundo grau devido às suas propriedades benéficas na regeneração tecidual. O presente estudo se configura como uma revisão bibliográfica integrativa, compilando informações de referências já publicadas para fornecer maior visibilidade e conectar o pesquisador à literatura existente sobre o tema. Isso contribui para aprofundar os conhecimentos sobre o assunto abordado e orientar pesquisas futuras. Se utilizou materiais científicos publicados em livros, periódicos nacionais e internacionais, sites e documentos de entidades ligadas à pesquisa científica. A revisão de literatura seguiu um processo sistemático e abrangente, composto por seis etapas: identificação do problema ou questão de pesquisa, estabelecimento de critérios de inclusão e exclusão de estudos, definição das informações a serem extraídas dos estudos selecionados, avaliação dos estudos, interpretação dos resultados e apresentação da síntese do conhecimento. Foram utilizadas bases de dados como SCIELO, LILACS, Public Medline e Google Acadêmico para a busca de artigos e teses pertinentes ao tema. A revisão de literatura ressaltou a necessidade de novos estudos acerca do objeto de estudo.
Case Report: Spectrum of interesting ocular manifestations following COVID-19 vaccination: a case series of real-world presentations
Authors: Tajunisah Iqbal , Tan Shao Sze , Effendi-Tenang Irina , Samsudin Amir , Ling Kiet-Phang , Tan Wee Yong , Ramasamy Sunder , Fong Kenneth Choong Sian 
Published: September 2023

PurposeWe report the ocular findings that patients experienced after receiving the coronavirus disease 2019 (COVID-19) vaccination in three different eye centers in Malaysia.ObservationsA total of four cases were reported. Three patients received the Pfizer-BioNTech vaccine, while the other received the Oxford AstraZeneca type. Ocular symptoms occurred after the first vaccine dose in two patients and after the second vaccine dose in the other two. Three out of four patients required active treatment for their vision complications postvaccination. The first patient had acute-onset retinal pigment epitheliitis within 3 h of vaccination and was treated conservatively. The second patient developed unilateral choroidal neovascularization 3 days after vaccination and required intravitreal antivascular endothelial growth factor injection. The third patient presented with bilateral acute multifocal placoid pigment epitheliopathy a week after vaccination and responded to intravenous methylprednisolone. The fourth patient presented with herpes zoster infection and unilateral anterior nongranulomatous uveitis 2 weeks after vaccination and was treated with oral acyclovir and topical corticosteroids. All patients reported some amount of visual recovery.Conclusions and importanceVisual symptoms and various ocular adverse events can occur following COVID-19 vaccination, which warrants further investigation and urgent intervention if necessary. We would suggest patients receiving the COVID-19 vaccination be aware of possible ocular complications and report any symptoms, regardless of severity.
A multicenter study on the application of artificial intelligence radiological characteristics to predict prognosis after percutaneous nephrolithotomy
Authors: Hou Jian , Wen Xiangyang , Qu Genyi , Chen Wenwen , Xu Xiang , Wu Guoqing , Ji Ruidong , Wei Genggeng , Liang Tuo , Huang Wenyan , Xiong Lin 
Published: September 2023

BackgroundA model to predict preoperative outcomes after percutaneous nephrolithotomy (PCNL) with renal staghorn stones is developed to be an essential preoperative consultation tool.ObjectiveIn this study, we constructed a predictive model for one-time stone clearance after PCNL for renal staghorn calculi, so as to predict the stone clearance rate of patients in one operation, and provide a reference direction for patients and clinicians.MethodsAccording to the 175 patients with renal staghorn stones undergoing PCNL at two centers, preoperative/postoperative variables were collected. After identifying characteristic variables using PCA analysis to avoid overfitting. A predictive model was developed for preoperative outcomes after PCNL in patients with renal staghorn stones. In addition, we repeatedly cross-validated their model’s predictive efficacy and clinical application using data from two different centers.ResultsThe study included 175 patients from two centers treated with PCNL. We used a training set and an external validation set. Radionics characteristics, deep migration learning, clinical characteristics, and DTL+Rad-signature were successfully constructed using machine learning based on patients’ pre/postoperative imaging characteristics and clinical variables using minimum absolute shrinkage and selection operator algorithms. In this study, DTL-Rad signal was found to be the outstanding predictor of stone clearance in patients with renal deer antler-like stones treated by PCNL. The DTL+Rad signature showed good discriminatory ability in both the training and external validation groups with AUC values of 0.871 (95% CI, 0.800-0.942) and 0.744 (95% CI, 0.617-0.871). The decision curve demonstrated the radiographic model’s clinical utility and illustrated specificities of 0.935 and 0.806, respectively.ConclusionWe found a prediction model combining imaging characteristics, neural networks, and clinical characteristics can be used as an effective preoperative prediction method.
A novel nomogram for identifying high-risk patients among active surveillance candidates with papillary thyroid microcarcinoma
Authors: Zhang Li , Wang Peisong , Li Kaixuan , Xue Shuai 
Published: September 2023

ObjectiveActive surveillance (AS) has been recommended as the first-line treatment strategy for low-risk (LR) papillary thyroid microcarcinoma (PTMC) according to the guidelines. However, preoperative imaging and fine-needle aspiration could not rule out a small group of patients with aggressive PTMC with large-volume lymph node micro-metastasis, extrathryoidal invasion to surrounding soft tissue, or high-grade malignancy from the AS candidates.MethodsAmong 2,809 PTMC patients, 2,473 patients were enrolled in this study according to the inclusion criteria. Backward stepwise multivariate logistic regression analysis was used to filter clinical characteristics and ultrasound features to identify independent predictors of high-risk (HR) patients. A nomogram was developed and validated according to selected risk factors for the identification of an HR subgroup among “LR” PTMC patients before operation.ResultsFor identifying independent risk factors, multivariable logistic regression analysis was performed using the backward stepwise method and revealed that male sex [3.91 (2.58–5.92)], older age [0.94 (0.92–0.96)], largest tumor diameter [26.7 (10.57–69.22)], bilaterality [1.44 (1.01–2.3)], and multifocality [1.14 (1.01–2.26)] were independent predictors of the HR group. Based on these independent risk factors, a nomogram model was developed for predicting the probability of HR. The C index was 0.806 (95% CI, 0.765–0.847), which indicated satisfactory accuracy of the nomogram in predicting the probability of HR.ConclusionTaken together, we developed and validated a nomogram model to predict HR of PTMC, which could be useful for patient counseling and facilitating treatment-related decision-making.
Relationship between sodium–glucose cotransporter-2 inhibitors and muscle atrophy in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
Authors: Xia Chengdong , Han Yufeng , Yin Chunhui , Geng Ruyue , Liu Zhenfei , Du Yongle , Yu Mingkun 
Published: September 2023

AimThis study aims to assess the association between sodium–glucose cotransporter type-2 inhibitor (SGLT-2i) treatment and muscle atrophy in patients with type 2 diabetes mellitus (T2DM).MethodsWe searched six databases from 1 January 2012 to 1 May 2023, without language restrictions. The primary outcome was muscle. Secondary outcomes were weight loss, weakness, malaise, or fatigue. Subgroup analyses were performed according to different definitions of muscle, treatment duration, and measurement methods. The quality of the studies was assessed using the Cochrane tool. The quality of the evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) tool.ResultsNineteen randomized controlled trials (RCTs) involving 1,482 participants were included. Compared with the control group, a meta-analysis showed that T2DM participants in the group treated with SGLT-2i demonstrated statistically significant reductions in lean body mass of 0.66 (95% confidence interval (CI), −1.05 to −0.27; p = 0.0009) and skeletal muscle mass of 0.35 (95% CI, −0.66 to −0.04; p = 0.03). No deaths or serious adverse events were reported. The quality of evidence in the included trials was low.ConclusionsSGLT-2i may lead to a reduction in muscle strength in the treatment of T2DM compared to the control group. However, there is still a lack of high-quality evidence to evaluate muscle atrophy caused by SGLT-2i.Systematic review registrationhttps://inplasy.com/inplasy-2022-12-0061/, identifier 2022120061.
MEA-based CO2 capture: a study focuses on MEA concentrations and process parameters
Authors: Wang Nan , Wang Dong , Krook-Riekkola Anna , Ji Xiaoyan 
Published: September 2023

CO2 capture using monoethanolamine (MEA) is one of the important decarbonization options and often considered as a benchmark, while the optimal MEA contraction and systematic process study are still lacking. In this work, firstly, the MEA concentrations between 15 and 30 wt% were studied from both process simulations with Aspen Plus and experimental measurements in the pilot-scale. 20 wt% MEA was identified as the preferable solution. Subsequently, a systematic analysis was conducted for CO2 capture using 20 wt% MEA with/without CO2 compression to study how various parameters, including gas flow rate, CO2 concentration, and CO2 removal rate, affected the energy demand and techno-economic performances quantitatively. The influence of each parameter on both energy demand and cost showed an obvious non-linear relationship, evidencing the importance of systematic analysis for further study on decarbonization. The evaluation indicated that the regeneration heat required the largest portion of energy demand. The economic analysis showed that the capital cost was more sensitive to the selected parameters than the operational cost, while the operational cost created a major change in the overall cost. In addition, the gas flow rate and CO2 concentration were the main parameters affecting the cost, rather than the CO2 removal rate. Finally, it was suggested that, for a new plant, CO2 capture showed the minimum investment cost per ton CO2 when operating the plant on a large scale, high CO2 concentration, and high CO2 removal rate; for an existing plant, the capture preferred to run with the high CO2 removal rate.
Digital resonant control of power converters under variable grid frequency conditions
Authors: Ijaz Muhammad , Nazir Rabia , Alhussein Musaed , Ahmad Jameel , Aurangzeb Khursheed , Saleem Faisal 
Published: September 2023

Introduction: The proportional resonant (PR) controller is known for its ability to effectively regulate sinusoidal current and voltage with low steady-state error. However, in the context of digital power systems, where operations are discrete in time, applying conventional PR controllers directly presents challenges. This study investigates the impact of various discretization methods on the performance of PR controllers, particularly under scenarios with varying reference frequencies.Methods: To assess the performance of digital PR controllers under varying reference frequency conditions, three discretization techniques are employed: zero-order hold (ZOH), impulse invariant (II), and zero pole matching (ZPM), in addition to the conventional deadbeat controller. These controllers are tested in conjunction with a single-phase pulse-width modulated (PWM) inverter, which is a crucial component in modern power systems.Results: Simulation results indicate the effectiveness of the different digital PR controllers in tracking both fixed and variable reference frequency signals while minimizing total harmonic distortion (THD) and steady-state error. When utilizing only the deadbeat controller, steady-state error and THD are measured at 4.9 V and 4.82%, respectively. However, the proposed ZPM-based digital PR controller significantly improves performance, reducing steady-state error to 0.12 V and THD to 0.45%, highlighting its superior performance.Discussion: The findings of this study emphasize the importance of choosing the appropriate discretization method when implementing PR controllers in digital power systems. The ZPM-based digital PR controller proves to be highly efficient in regulating power converters under varying grid frequency conditions. This research contributes to the understanding of digital PR controller behavior and its potential for improving power system performance, especially in scenarios with intermittent renewable energy resources and fluctuating grid frequencies.
Insight into Nrf2: a bibliometric and visual analysis from 2000 to 2022
Authors: Ma Yawei , Wang Zhongqing , Hu Yuedong 
Published: September 2023

Background: Nrf2 plays a pivotal role in governing the antioxidant defense system, triggering the transcription of diverse genes involved in cellular protection. Its role in mitigating oxidative damage and modulating inflammatory processes has made Nrf2 an attractive target for therapeutic interventions. Despite the growing interest in Nrf2 research, a bibliometric analysis is relatively rare. This study aimed to clarify Nrf2’s role in multiple diseases, identify emerging trends and hotspots using bibliometric analysis, and provide valuable insights and potential directions for future therapeutic interventions.Methods: The Science Citation Index of Web of Science Core library from 2000 to 2022 was searched on 22 October 2022. Use Microsoft Excel, CiteSpace, Bibliometrix, and VOS viewers for data collection and visualization of research focus and trends.Results: A vast collection of 22,040 research studies on Nrf2 published between 2000 and 2022 were identified. Nrf2 research has seen significant growth globally from 2000 to 2022. China leaded in publication numbers (9,623, 43.66%), while the United States dominated in citation frequency with 261,776 citations. China Medical University was the most productive institutions (459, 2.08%). Masayuki Yamamoto topped in publications (307), while Itoh K. ranked first in citations with 3669. Free Radical Biology and Medicine was the journal with the most studies and citations on Nrf2 (613, 29,687 citations). The analysis of keyword clustering enhanced the categorization of topics and can be summarized as oxidative stress, cancer, disorders in glycolipid metabolism, inflammation, and neurological conditions.Conclusion: China and the United States are the pioneers in Nrf2 research. Recently, there has been a comprehensive exploration of Nrf2 involving both experimental and clinical aspects, as well as mechanisms and therapeutic applications. Investigating novel molecular mechanisms, including NF-κB, Ho1, and Keap1, and developing enhanced, targeted Nrf2 activators or inhibitors to uncover the interplay among cancer, glycolipid metabolic disorder, inflammation, and neurological disorders will be upcoming trends and hotspots.
Remote detection of fungal pathogens in viticulture using laser-induced fluorescence: an experimental study on infected potted vines
Authors: Kölbl Christoph , Diedrich Manu , Ellingen Elias , Duschek Frank , Selim Moustafa , Berkelmann-Löhnertz Beate 
Published: September 2023

IntroductionPathogenic fungi, such as Plasmopara viticola and Erysiphe necator, severely threaten the annual yield of grapes in both quantity and quality. In contrast to other crop production systems, fungicides are intensively applied in viticulture as a countermeasure. The goal of precision viticulture is to optimize vineyard performance as well as the environmental impact by reducing fungicides and applying different techniques and combined strategies. Therefore, new emerging technologies are required, including non-invasive detection, as well as monitoring and tools for the early and in-field detection of fungal development. MethodsIn this study, we investigated leaves of potted vines (Vitis vinifera cv. ‘Riesling’) and traced the development of the inoculated leaves using our new remote detection system vinoLAS®, which is based on laser-induced fluorescence spectroscopy. We ran a measurement campaign over a period of 17 days.ResultsWe were able to detect a leaf infection with P. viticola, the causal agent of downy mildew, between 5 and 7 days after inoculation. Our results provide evidence for a successful application of laser-based standoff detection in vineyard management in the future. Thus, the vinoLAS system can serve as a model technology for the detection of pathogenic disease symptoms and thus monitoring complete vineyard sites. This allows for early countermeasures with suitable crop protection approaches and selected hot-spot treatments.DiscussionAs P. viticola is considered one of the most damaging fungi in European viticulture, disease mapping via this monitoring tool will help to reduce fungicide applications, and will, therefore, support the implementation of the European Green Deal claims.