bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationships between pain‐associated psychological distress, pain intensity, patient expectations, and physical function in individuals with musculoskeletal pain: A retrospective cohort study
Authors: Leech Joseph B. , MacPherson Kevin L. , Klopper Mareli , Shumway Joshua , Salvatori Robert T. , Rhon Daniel I. , Young Jodi L. 
Published: April 2023

AbstractIntroductionThe presence of pain‐associated psychological distress (PAPD) in musculoskeletal disorders, including negative mood, fear‐avoidance, and lack of positive affect/coping, is associated with prolonged disability. The importance of considering psychological influence on pain is well known, but practical ways of addressing it are not as straightforward. Identifying relationships between PAPD and pain intensity, patient expectations, and physical function may guide the development of future studies that assess causality and inform clinical practice.ObjectiveTo assess the relationship between PAPD measured by the Optimal Screening for Prediction of Referral and Outcome—Yellow Flag tool, and baseline pain intensity, expectations of treatment effectiveness, and self‐reported physical function at discharge.DesignRetrospective cohort study.SettingHospital‐based outpatient physical therapy.ParticipantsPatients 18 to 90 years old with spinal pain or lower extremity osteoarthritis.Main Outcome MeasuresPain intensity and patient expectations of treatment effectiveness at intake, and self‐reported physical function at discharge.ResultsA total of 534 patients, 56.2% female, median (interquartile range [IQR]) age 61 (21) years with an episode of care between November 2019 and January 2021 were included. A multiple linear regression showed a significant association between PAPD and pain intensity with 6.4% (p < .001) of the variance explained. PAPD explained 3.3% (p < .001) of the variance in patient expectations. One additional yellow flag present resulted in a 0.17‐point increase in pain intensity and 1.3% decrease in patient expectations. PAPD was also associated with physical function with 3.2% (p < .001) of the variance explained. PAPD explained 9.1% (p < .001) of the variance in physical function at discharge in the low back pain cohort only when assessed independently by body region.ConclusionThese findings support the theory that the pain experience is complex and multiple factors should be considered when evaluating a patient with musculoskeletal pain. Clinicians who have identified PAPD may consider these relationships when planning or modifying interventions and pursuing multidisciplinary collaboration.
Research on wake interval of paired departure at closely spaced parallel runways
Authors: Gao Haoran , Liu Cheng , Chen Yaqing , He Xin 
Published: April 2023

AbstractTo assess and improve the operation system of paired takeoff separation and reduce the risk of wake turbulence encounters during paired takeoff, a computational fluid dynamics (CFD) method is used to study the operational conditions and wake turbulence safety intervals of paired takeoff separation mode. Firstly, the safe area of wake turbulence under the paired takeoff separation mode is analyzed, and a safety interval model is constructed. Secondly, the SST k‐ω turbulence model is selected, and a numerical simulation method for the wake flow of the leading aircraft before the pairing is established based on CFD. Finally, a calculation method for the safety interval of paired takeoff separation is established. Taking Hongqiao Airport as an example, A320‐200 and B737‐800 are selected as the leading and trailing aircraft, and the wake flow field is simulated at 0, −1, and −2 m/s crosswind conditions. The simulation results are then used to analyze the operational conditions and safety intervals of paired takeoff separation mode. The results provide data support for the implementation of the paired takeoff separation mode and demonstrate the applicability of the CFD method in studying aircraft wake turbulence.
Mini Review on The Synthesis and Biological Impact of Thiazoles
Authors: Ayman Manar , Abdelmonsef Aboubakr H. , Rashdan Huda R. M. 
Published: April 2023

AbstractThis review discusses the most recently reported documents available on the chemistry of thiazoles. In addition, it covers the biological impact of different thiazole based compounds. The information mentioned in this review about the different physico‐chemical characters’ and synthetic paths of such important heterocyclic system take especial attraction and consideration of the biomedicinal chemists to make combinatorial library and exert more efforts in the search of thiazoles.
Activating Joy Through Culturally and Historically Responsive Read‐Alouds
Authors: Vlach Saba K. , Lentz Tova S. , Muhammad Gholnecsar E. 
Published: April 2023

AbstractActivating joy is a rigorous and serious pursuit in literacy education. In this article, we guide educators through the framework of culturally and historically responsive education and its five pursuits: identity, skills, intellect, criticality, and joy. Our focus is on the fifth pursuit ‐joy– and we support elementary school teachers in pursuing joy during read‐aloud in their classrooms. As we advocate for activating joy during read‐aloud, we ask educators to consider joy and its relationship to justice and humanity. We suggest that to activate joy, educators must start with stories that center and celebrate our young people, their lived experiences, and their histories from a place of self‐empowerment. We offer practical examples of culturally and historically responsive read‐alouds that center five types of joy.
The HNRNPF/H RNA binding proteins and disease
Authors: Brownmiller Tayvia , Caplen Natasha J. 
Published: April 2023

AbstractThe members of the HNRNPF/H family of heterogeneous nuclear RNA proteins—HNRNPF, HNRNPH1, HNRNPH2, HNRNPH3, and GRSF1, are critical regulators of RNA maturation. Documented functions of these proteins include regulating splicing, particularly alternative splicing, 5′ capping and 3′ polyadenylation of RNAs, and RNA export. The assignment of these proteins to the HNRNPF/H protein family members relates to differences in the amino acid composition of their RNA recognition motifs, which differ from those of other RNA binding proteins (RBPs). HNRNPF/H proteins typically bind RNA sequences enriched with guanine (G) residues, including sequences that, in the presence of a cation, have the potential to form higher‐order G‐quadruplex structures. The need to further investigate members of the HNRNPF/H family of RBPs has intensified with the recent descriptions of their involvement in several disease states, including the pediatric tumor Ewing sarcoma and the hematological malignancy mantle cell lymphoma; newly described groups of developmental syndromes; and neuronal‐related disorders, including addictive behavior. Here, to foster the study of the HNRNPF/H family of RBPs, we discuss features of the genes encoding these proteins, their structures and functions, and emerging contributions to disease.This article is categorized under:
RNA in Disease and Development > RNA in Disease
RNA Processing > Splicing Regulation/Alternative Splicing
RNA Interactions with Proteins and Other Molecules > Protein–RNA Interactions: Functional Implications
Local- and Small-Scale Atmospheric Dispersion Modeling Towards Complex Terrain and Building Layout Scenario Using Micro-Swift-Spray
Authors: Dong Xinwen , Zhuang Shuhan , Fang Sheng 
Published: April 2023

AbstractAtmospheric dispersion models (ADMs) have been widely used in simulating the contamination from released pollutants, which supports the emergency response and assist the inverse modeling for unknown source, due to its balance between accuracy and speed of calculation. The Micro-SWIFT-SPRAY modeling system (MSS) is one of the candidates that are able to accurately reproduce the wind and concentration fields with inputs of meteorology, topography, and source information. The obstacle treatments benefit its performance over dense buildings. Applying the optimal parameters to MSS, both the local and small-scale simulations were carried out in the vicinity of the same nuclear power plant (NPP) site with dense buildings and surrounded by mountains and sea. In these scenarios, the airflows came from the NE direction and cross over the sea and buildings to mountains. Both the wind and concentration results were evaluated against the measurements of two wind tunnel experiments. The results demonstrate that MSS can reproduce the variations of wind and concentration towards the changes in terrain elevation or building layout. The local-scale simulation well matches the measurements in the mountain area, whereas the small-scale one better reconstructs those around the buildings. The clusters of wind direction and speed are found that result from the topography of monitoring networks. The high concentration area around the release position is successfully reproduced, which indicates the turbulence is sufficient facing complex obstacles. Besides, MSS outperforms the concentration simulations in the local-scale scenario with a FAC5 of 0.710 and a FB of −0.010. However, the VG of the local-scale scenario reaches 15.510 meaning many extremes are introduced. The small-scale scenario obtains a lower VG of 2.303. Considering different performance dominances of two scales, nesting grids may bring improvement in the case both the simulations in the mountain and building areas are meant for the emergency response.
Discussion on the Reporting of Nuclear Safety Incident from the Perspective of Media Ecology
Authors: Li Yang , Yao Li Jie 
Published: April 2023

AbstractNuclear safety events report is an important part of news reports related to nuclear power. Correct and appropriate reporting is very important for the positive development of public opinion and the emotional guidance of the public in China, and it also directly reflects the overall level of China’s nuclear safety culture construction. Based on the media ecology, this paper studies the evolution of the concept and way of accident reporting in China, and taking the recent report of Taishan nuclear power incident in 2021 as an example, discusses the differences and changes in several public opinions in the brand-new media ecology mode, such as the report way, the report idea and narrative subject, and puts forward a new perspective and thinking, and holds that we should seek truth from facts, be scientific and rigorous, use appropriate reporting and public communication methods, and take advantage of news language and different narrative subjects to make the real situation. I hope the new perspective of this paper can provide reference for future related work, and maintain the healthy and upward development of our nuclear safety culture atmosphere.
Development Prospect and Application of Nuclear District Heating in China
Authors: Zhang Yifan , Li Wenan , Yu Qian 
Published: April 2023

AbstractWith the increase of heating demand, in order to further expand the heat source channels and promote China’s clean heating work, this paper investigates the development status of nuclear regional heating at home and abroad, explores the development prospect of China’s nuclear heating industry, and discusses the difficulties encountered in the future application and the corresponding solutions. The research results show that China’s nuclear heating has broad development prospects, but there are some problems in the construction of regional heating network and the safety, reliability and economy of nuclear power plant operation, and put forward targeted solutions, so as to promote the wide application of nuclear regional heating and realize the sustainable development of economy.
Effect of β-Phase Heat Treatment on Microstructure of Zr-Sn-Nb-Fe Alloy
Authors: Cui Yiran , Yang Zhongbo , Zhang Wei , Liu Hong 
Published: April 2023

AbstractZirconium alloys are extensively used in nuclear fuel element cladding tube, guide tube and positioning spacer grid and other reactor core structural materials because of their excellent nuclear properties. The preparation of these profiles includes ingot forging, β-phase heat treatment, hot and cold deformation processing and other processes. Among them, The β-phase heat treatment process significantly affects the microstructure and processability of zirconium alloys forging billets. OM, SEM and TEM were used to study the microstructure of Zr-0.85Sn-1Nb-0.3Fe alloy forging ingot samples after β-phase heat treatment at (950–1150 °C)/(15 min–2 h), and water quenching. The results indicated that under different heat treatment conditions, typical acicular shape martensitic microstructure appears in Zr-Sn-Nb-Fe alloy after water quenching. The size of martensitic laths increased with the extension of holding time, which showed that the length and width of the small part of the acicular martensite away from the forging plane both increased significantly; on this basis, the effects of β-phase heat treatment temperature and holding time on the phase transformation behavior of the alloy were analyzed.
Mechanical and Numerical Simulation Analysis for the Insertion Section Sampling of Irradiation Charpy Specimen Reconstitution
Authors: Tang Yunpeng , Qi Muran , Zhu Huiping , Tong Zhenfeng , Wang Chenglong 
Published: April 2023

AbstractThe reactor pressure vessel (RPV) is one of the most critical equipment in the pressurized water reactor, and its structural integrity is the key factor that determines the operational safety and service life of the reactor. In practical applications, the aging degree of RPV can be evaluated through the ductile-brittle transition temperature (DBTT) curve of the Charpy impact specimen pre-placed in RPV. However, due to the space limitation inside the reactor core, the available irradiation surveillance specimens are limited for mechanical testing. Especially, most reactors have faced the problem of life extension in recent years, and the impact data of the irradiation surveillance specimen is an important basis for the life extension of the reactor. One of the solutions is to reconstitute new Charpy specimens from the impacted ones to obtain more impact data. In this paper, the basic methods for the reconstitution of RPV material Ni-Cr-Mo-V steel are studied. By testing the hardness change of the Charpy impact broken specimen along the length direction, the maximum value of the plastic deformation zone of the impact fracture is obtained. Besides, based on the Gurson-Tvergaard-Needleman (GTN) model, the impact process of the material in the upper shelf temperature region is calculated by ABAQUS numerical simulation. Compared with the tested microhardness results of the material, the maximum length of the insert section of Charpy impact specimen reconstitution is confirmed. It shows that for Ni-Cr-Mo-V steel, the maximum length of the plastic deformation zone at the upper shelf temperature region is about 7 mm, and the insert length of the reconstituted specimens can be selected to 20 mm. The results can be used as an important reference for establishing the fabrication standard of the reconstituted Charpy specimen of the reactor pressure vessel.
Research on Atmospheric Dispersion Factor Used in the Calculation of Emergency Planning Zone
Authors: Cao Qun , Qiu Lin 
Published: April 2023

AbstractReasonable division of emergency planning zones is an important technical basis for emergency preparedness and responses. In order to evaluate the size of the emergency planning zone, it’s important to determine the appropriate atmospheric dispersion factor based on the realistic site conditions to calculate the dose consequences caused by the accident through the radioactive plume. This paper introduces the current progress in the calculation of emergency planning zoning for different reactor nuclear power plant sites, the general method of determining the emergency planning zone in China and puts forward the method for optimizing the calculation of the atmospheric dispersion factor used in the emergency planning zoning for HPR1000 nuclear power plant site. Based on the theoretical analysis and comparison of the current main calculation models of atmospheric dispersion factor, this paper is devoted to the feasibility analysis of use of Gaussian puff models in the EPZ calculation considering the light wind and the calm wind condition, which can obtain the convergence results. This model can fully consider the dispersion process, spatial variation of meteorological fields, topographic effects and accumulation of pollutants and greatly improve the calculation accuracy. To solve the problems of low calculation speed brought by Gaussian puff models used in the EPZ calculation, the paper makes a theoretical analysis of the current main weather sampling methods and puts forward the stratified random sampling method to improve the speed of EPZ calculation. This method can select representative weather samples from the annual weather sequences to represent the annual situation so as to speed up the calculation without affecting the calculation accuracy.
Hazard Identification on the Process of High-Level Liquid Waste Concentration and Denitration in Spent Fuel Reprocessing by HAZOP
Authors: Wang Weishuai , Liu Xuegang , He Qian-ge , Wang Xinghai 
Published: April 2023

AbstractTo develop China’s spent nuclear fuel reprocessing, safety analysis of reprocessing facility is of great importance and high priority. Any methodology of safety analysis, no matter whether it is in a kind of deterministic analysis, probabilistic assessment or so-called Integrated Safety Analysis, is beginning with the identification and systematic analysis of hazards as the very first essential step. Recognizing that reprocessing facilities are, to a large extent, chemical processing plants, HAZard and OPerability analysis (HAZOP) was introduced firstly in the US. It is featured as one of the most suitable methods for performing detailed identification of a wide range of hazards.In this paper, our work on part of the concentration and denitration process (C/D process) of high-level liquid waste (HLLW) was revealed to exemplify the procedure of hazard identification and analysis for a typical reprocessing process, as the C/D process of HLLW has many symbolic features of spent fuel reprocessing, such as high radiation, various chemicals, complex chemical reactions and operation stages. The purpose of this paper was to test the applicability of HAZOP for a typical process in reprocessing.The HAZOP approach was starting with the identifications of process, reactions, equipment, and system borders. Base on the features of the given system (part), specific elements and guidewords were selected and combined to generate deviations for different operation stages. The possible causes and consequences of deviation as well as existing safeguards were taken into consideration. To make the workflow of HAZOP complete and underscore its significance, a 4-by-5 risk matrix was established to evaluate the risk levels of all consequences resulted from deviations, based on the severity of consequence and associated likelihood of occurrence.The final results were shown in a HAZOP analysis worksheet, in which twenty-two deviations were presented, revealing the potential hazards found in the C/D part. After a preliminary risk assessment using a risk matrix, eight of them were recognized as undesirable risks (only accepted when risk reduction is impracticable). The results verified that the HAZOP analysis was suitable for the processes or parts involved with high radiation and complex chemical reactions in reprocessing facilities.
Development of Subchannel Code for Plate-Type Fuel Plus Verification
Authors: Zhang Bo , Jiang Gefan , Zhai Peichao , Shan JianQiang 
Published: April 2023

AbstractThe fuel shape and flow path structure of the plate-type fuel reactor are different from those of the conventional rod-bundle reactor, which leads to the difference between the thermal-hydraulic phenomenon and thermal conduction in the rod bundle assembly. Therefore, in this thesis, the subchannel analysis model and code applied to the plate-type fuel reactor are developed. The calculation results of the code are compared with the simulation results of FLUENT and MATRA and the experimental results of the flow and heat transfer of the rectangular channel, so that the code is verified.This thesis first fully investigated the thermal-hydraulic and friction models applicable to rectangular flow channels, and developed the plate-type fuel heat conduction model and flow redistribution model. On the basis of the existing two-fluid three-field subchannel code, the subchannel analysis software for the plate type fuel reactor was developed. The comparison with the rectangular channel heat transfer experiment shows that the code can accurately predict the heat transfer coefficient under the rectangular channel. The comparison and verification with the simulation calculation results of the MTR reactor under steady-state conditions with the FLUENT and MATRA codes show that the developed subchannel code can simulate the thermal-hydraulic phenomena of the plate fuel assembly. Finally, according to the calculation results of the MTR reactor by the code, the thermal-hydraulic characteristics of the plate fuel reactor are analyzed, and the safety of the plate fuel is evaluated.
A Moose-Based Neutron Diffusion Code with Application to a LMFR Benchmark
Authors: Wang Weixiang , Feng WenPei , Zhang KeFan , Yang Guangliang , Ding Tao , Chen Hongli 
Published: April 2023

AbstractMOOSE (Multiphysics Object-Oriented Simulation Environment) is a powerful finite element multi-physics coupling framework, whose object-oriented, extensive system is conducive to the development of various simulation tools. In this work, a full-core MOOSE-based Neutron Diffusion application is developed, and a 3D PWR benchmark 3D-IAEA with given group constants is applied for code verification. Then the MOOSE-based Neutron Diffusion application is applied to the calculation of a Sodium-cooled Fast Reactor (SFR) benchmark, together with the research on homogenized few-group constants generation based on Monte Carlo method. The calculation adopts a 33-group cross section sets, which is generated using Monte Carlo code OpenMC. Considering the long neutron free path and strong global neutron spectrum coupling of liquid metal cooled reactor (LMFR), a full-core homogeneous model is used in OpenMC to generate the homogenized few-group constants. In addition, transport correction is used in the process of cross section generation, considering the prominent anisotropic scattering of fast reactor. The calculated results, including effective multiplication factor (keff) and assembly power distributions, are in good agreement with the reference values and the calculation results of OpenMC, which proves the accuracy of the neutron diffusion application, and also shows that the Monte Carlo method can be applied to generation of homogenized few-group constants for LMFR analysis.
Research on High-Performance Concrete for Volute Region of PX Combined Pump Room in Hualong Nuclear Power Plant
Authors: Liu Xiangkun , Zhou Chongxu , Hu Dehua , Zhang Wei 
Published: April 2023

AbstractAiming at the volute area concrete structure design requirements for PX combined pump room of HUALONG, the high performance concrete with wonderful property resistance to harmful ion erosion was made by optimization design. The strength grade of the concrete is CF50. Based on experimental result, its slump was 195 mm, its compressive strength was 60.9 MPa with the chloride ion permeability coefficient was 3.6 × 10−12 m2/s at twenty-eight days, and the restrained expansion rate was 2.7 × 10–4 with the dry shrinkage rate was 1.3 × 10–4. All the technical indexes conform to the design and construction requirements. Verified by engineering application, concrete compressive strength during continuous production period was according to the evaluation criteria of GB/T 50107-2010. And the standard deviations were only 1.64 MPa. It indicates that the concrete quality is stable and controlled.