bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biphasic positive airway pressure in the management of acute respiratory distress syndrome: a comparative study
Authors: Salem Shymaa Sayed , Hussein Khaled , Badawy M. Sh. , Gad Gad s , Rashad Alaa 
Published: May 2023

Abstract
Background
Biphasic positive airway pressure, also known as BIPAP, is a type of pressure-controlled ventilation that permits unrestricted spontaneous breathing at any time during the ventilatory cycle. Our study’s objective was to compare BIPAP’s effects on ARDS patients with those of the synchronized intermittent mandatory ventilation with pressure control (SIMV-PC) mode.

Results
The present observational, cross-sectional study was conducted on 40 ARDS patients of both sex. These patients were admitted to the intensive care unit, at Qena University Hospital, from April 2019 to November 2021. They were categorized into two groups at random, with group (A) patients receiving BIPAP mode and group (B) patients receiving (SIMV-PC) mode. Changes in arterial blood gases, hemodynamics, and lung mechanics (mean airway pressure, minute volume, tidal volume, compliance, and pressure limit) were compared in both groups after 24 h. There were no differences in the baseline clinical data, demographic, hemodynamic, arterial blood gases, and mortality between the two groups. Follow-up data after 24 h showed that BIPAP was associated with better hemodynamics, oxygenation, and lung mechanics (mean airway pressure, minute volume, and tidal volume). Fewer days of sedation requirements and mechanical ventilation in BIPAP compared to SIMV PC during the duration of the study.

Conclusions
In ARDS patients, BIPAP can improve oxygenation, hemodynamics, lung mechanics, decrease sedation use, and decrease duration of mechanical ventilation.

Trial registration
BIPAP in the Management of Acute Respiratory Distress Syndrome, ID: NCT05483959 Retrospectivelyregistered,https://register.clinicaltrials.gov/prs/app/template/EditRecord.vm?epmode=View&listmode=Edit&uid=U0003OBB&ts=12&sid=S00078AY&cx=9n7oml. Registered on 1 August 2022.
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling
Authors: Chen Zhao-Rong , Hong Yu , Wen Shi-Hong , Zhan Ya-Qing , Huang Wen-Qi 
Published: May 2023

BACKGROUND:
Myocardial infarction is a common perioperative complication, and blood flow restoration causes ischemia/reperfusion injury (IRI). Dexmedetomidine (DEX) pretreatment can protect against cardiac IRI, but the mechanism is still insufficiently understood.

METHODS:
In vivo, myocardial ischemia/reperfusion (30 minutes/120 minutes) was induced via ligation and then reperfusion of the left anterior descending coronary artery (LAD) in mice. Intravenous infusion of 10 μg/kg DEX was performed 20 minutes before ligation. Moreover, the α2-adrenoreceptor antagonist Yohimbine and STAT3 inhibitor Stattic were applied 30 minutes ahead of DEX infusion. In vitro, hypoxia/reoxygenation (H/R) with DEX pretreatment for 1 hour was performed in isolated neonatal rat cardiomyocytes. In addition, Stattic was applied before DEX pretreatment.

RESULTS:
In the mouse cardiac ischemia/reperfusion model, DEX pretreatment lowered the serum creatine kinase-MB isoenzyme (CK-MB) levels (2.47 ± 0.165 vs 1.55 ± 0.183; P < .0001), downregulated the inflammatory response (P ≤ .0303), decreased 4-hydroxynonenal (4-HNE) production and cell apoptosis (P = .0074), and promoted the phosphorylation of STAT3 (4.94 ± 0.690 vs 6.68 ± 0.710, P = .0001), which could be blunted by Yohimbine and Stattic. The bioinformatic analysis of differentially expressed mRNAs further confirmed that STAT3 signaling might be involved in the cardioprotection of DEX. Upon H/R treatment in isolated neonatal rat cardiomyocytes, 5 μM DEX pretreatment improved cell viability (P = .0005), inhibited reactive oxygen species (ROS) production and calcium overload (both P ≤ .0040), decreased cell apoptosis (P = .0470), and promoted STAT3 phosphorylation at Tyr705 (0.102 ± 0.0224 vs 0.297 ± 0.0937; P < .0001) and Ser727 (0.586 ± 0.177 vs 0.886 ± 0.0546; P = .0157), which could be abolished by Stattic.

CONCLUSIONS:
DEX pretreatment protects against myocardial IRI, presumably by promoting STAT3 phosphorylation via the α2-adrenoreceptor in vivo and in vitro.
Assessment of Temporomandibular Joint for Occurrence and Severity of Disorders in Adult Cases with Unilateral Cleft Lip and Palate and Non-Cleft Class I Using Helkimo Index
Authors: Kumar Nikhil , Daigavane Pallavi 
Published: May 2023

Background: Cleft lip and palate is congenital anomalies. Cleft patients are more akin toward surgical treatment plan neglecting the dental treatment aspects as aesthetic is main concern of patient bond to have malocclusion. Which may contribute to Temporomandibular joint disorder (TMDs) in cleft patients. Methods: A total 40 patients (20 cleft patients and 20 non cleft class I) were taken in the study. patients’ selection was done based on inclusion and exclusion criteria. Helkimo index was used for both subjective and clinical assessment for TMDs in both groups. Results: Cleft patients shows significant symptom of TMD between range of mild to severe while non cleft I cases showing mostly mild to moderate symptom of TMDs. Conclusions: It was found that Unilateral cleft lip and palate (UCLP) cases shows higher occurrence of TMDs in comparison with non-cleft class I group.
O LETRAMENTO DIGITAL EM TEMPOS DE PLATAFORMIZAÇÃO DA EDUCAÇÃO E AS POSSIBILIDADES PARA O ENSINO DE HISTÓRIA.
Authors: Rodrigues de Oliveira Max Fabiano 
Published: May 2023

ResumoEste artigo reflete sobre a importância do letramento digital de professoras e professores que atuam no ensino básico. Além de observar a importância de um letramento midiático que dê conta não apenas de questões operacionais, mas também se debruce para o estudo do funcionamento da rede em relação a privacidade de dados de crianças e adolescentes em um cenário de plataformização da educação e comportamento algorítmico que customiza aquilo que deve ou não aparecer em feeds infinitos. Há uma grande necessidade de formação continuada que busque o aperfeiçoamento desses docentes no que se refere ao uso das novas tecnologias digitais de informação e comunicação, as chamadas (NTICs). Letrados digitalmente, professores e estudantes, tornam-se peças fundamentais para combater a disseminação do discurso de ódio, fake news e a desinformação. Palavras-chave: Letramento digital; fake news; discurso de ódio; ensino de história
POČÍTAČOVÁ SIMULACE ZRANĚNÍ CHLAPCE NA ZADNÍM SEDADLE OSOBNÍHO VOZIDLA
Authors: Pavlata Petr 
Published: May 2023

Příspěvek se zabývá využitím moderních simulačních technik s podporou sw VPS (Virtual Performance System) a škálovatelnýho biomechanickým modelem lidského těla Virthuman při řešení silniční nehody s těžkým zraněním chlapce, sedícího na dětské sedačce na zadním sedadle osobního vozidla. Závěry analýzy naznačují, že chlapec v rozporu s předchozím tvrzením nebyl připoután. S podporou a využitím výše uvedeného sw a modelu, bylo možné zprěsnit výpočtové vymezení střetové rychlosti silničního vozidla.
Microwave target location method based on the diamond NV color center
Authors: Liu Yusong , Wang Qi , Qin Yue , Guo Hao , Li Jie , Li Zhonghao , Wen Huanfei , Ma Zongmin , Tang Jun , Liu Jun 
Published: May 2023

We propose a method for microwave target source localization based on the diamond
nitrogen vacancy color center. We use coherent population oscillation
effect and modulation and demodulation techniques to achieve the
detection of microwave intensity of microwave target sources, with a
minimum detection intensity of 0.59 µW. Positioning of
the microwave source was achieved within 50×100cm2 distance from the system 1 m
away using the cubic spline interpolation algorithm and minimum mean
squared error. The maximum positioning error was 3.5 cm. This
method provides a new, to the best of our knowledge, idea for the
passive localization of microwave targets.
Automatic classification of patients with myocardial infarction or myocarditis based only on clinical data: A quick response
Authors: Rahman Sheikh Shah Mohammad Motiur , Chen Zhihao , Lalande Alain , Decourselle Thomas , Cochet Alexandre , Pommier Thibaut , Cottin Yves , Salomon Michel , Couturier Raphaël 
Published: May 2023

Background
In acute cardiovascular disease management, the delay between the admission in a hospital emergency department and the assessment of the disease from a Delayed Enhancement cardiac MRI (DE-MRI) scan is one of the barriers for an immediate management of patients with suspected myocardial infarction or myocarditis.

Objectives
This work targets patients who arrive at the hospital with chest pain and are suspected of having a myocardial infarction or a myocarditis. The main objective is to classify these patients based solely on clinical data in order to provide an early accurate diagnosis.

Methods
Machine learning (ML) and ensemble approaches have been used to construct a framework to automatically classify the patients according to their clinical conditions. 10-fold cross-validation is used during the model’s training to avoid overfitting. Approaches such as Stratified, Over-sampling, Under-sampling, NearMiss, and SMOTE were tested in order to address the imbalance of the data (i.e. proportion of cases per pathology). The ground truth is provided by a DE-MRI exam (normal exam, myocarditis or myocardial infarction).

Results
The stacked generalization technique with Over-sampling seems to be the best one providing more than 97% of accuracy corresponding to 11 wrong classifications among 537 cases. Generally speaking, ensemble classifiers such as Stacking provided the best prediction. The five most important features are troponin, age, tobacco, sex and FEVG calculated from echocardiography.

Conclusion
Our study provides a reliable approach to classify the patients in emergency department between myocarditis, myocardial infarction or other patient condition from only clinical information, considering DE-MRI as ground-truth. Among the different machine learning and ensemble techniques tested, the stacked generalization technique is the best one providing an accuracy of 97.4%. This automatic classification could provide a quick answer before imaging exam such as cardiovascular MRI depending on the patient’s condition.
Severe Mpox Proctitis Complicated by Bowel Obstruction
Authors: Saleh Hasan , Ho Bao T. , Call Justin T. , Plante Marie M. , Zaver Himesh B. , Powers Harry R. , Metcalfe Allie M. , Graham Charles G. , Lewis Michele D. 
Published: May 2023

ABSTRACT
Mpox is a rare infection caused by the zoonotic orthopoxvirus. We present the case of a 44-year-old man with HIV and a history of kidney transplant who presented with mpox and developed proctitis-associated bowel obstruction, urinary retention, and eosinophilia. Our case highlights potential gastrointestinal manifestations of severe mpox infection.
APA ARTINYA MENJADI YOUTUBER? ANALISIS FENOMENOLOGIS INTERPRETATIF TENTANG PENGALAMAN MENJADI YOUTUBER
Authors: Pratama Herryan Rudi , Kahija Yohanis Franz La 
Published: May 2023

Penelitian mengenai YouTuber sebagai profesi baru di era kemajuan teknologi saat ini dari sudut pandang keilmuan psikologi masih jarang dilakukan. Padahal, dalam beberapa kasus terdapat pelaku profesi YouTuber yang rentan mengalami permasalahan kesehatan mental, seperti depresi akibat banyaknya tekanan, hujatan, dan beban kerja yang dijalani, terlepas dari banyaknya pandangan bahwa YouTuber merupakan pekerjaan fleksibel yang dapat menghasilkan uang dalam jumlah yang tidak sedikit. Maka dari itu, penelitian ini akan mengeksplorasi tentang bagaimana YouTuber menjalani pekerjaannya beserta segala dinamika yang menyertai. Tujuan penelitian ini adalah untuk memahami bagaimana partisipan memaknai pengalaman subjektifnya dalam menjalani pekerjaan sebagai YouTuber. Partisipan penelitian terdiri dari tiga orang YouTuber yang dipilih berdasarkan metode sampling purposif. Penggalian data dilakukan dengan melakukan wawancara secara semi terstruktur. Transkrip wawancara kemudian dianalisis dengan menggunakan metode analisis fenomenologis interpretatif. Pada penelitian ini terdapat delapan tema superordinat yang ditemukan : (1) totalitas dalam bekerja, (2) optimisme dalam bekerja, (3) tantangan pekerjaan, (4) penghasilan sebagai orientasi pekerjaan, (5) pemahaman terhadap profesi YouTuber, (6) interaksi dengan penonton, (7) presentasi diri, (8) pengaruh dari perlakuan tidak menyenangkan dan satu tema khusus, yaitu dorongan berperilaku altruis.
PENGARUH PELATIHAN SELF-COMPASSION SECARA DARING UNTUK MENINGKATKAN PENERIMAAN DIRI PADA MAHASISWA DENGAN FOBIA SPESIFIK RINGAN
Authors: Indrawati Nur Diana , Kaloeti Dian Veronika Sakti 
Published: May 2023

Mahasiswa tahun pertama kuliah perlu menguasai cara mengatur lingkungan sosial yang baru, sehingga individu harus menyesuaikan dengan lingkungan mereka, mengembangkan identitas diri mereka dan membentuk hubungan dekat dengan orang lain. Mahasiswa yang berjuang dengan fobia akan lebih sulit untuk memiliki penerimaan diri. Pelatihan self-compassion disebutkan dapat membantu individu untuk meningkatkan emosi positif dalam diri mereka. Penelitian ini bertujuan untuk mengetahui efektivitas pelatihan self-compassion secara daring untuk meningkatkan penerimaan diri pada mahasiswa tahun pertama dengan fobia spesifik ringan. Desain yang digunakan yaitu randomized pretest-postest control group design. Subjek dalam penelitian ini adalah mahasiswa baru dengan tingkat fobia spesifik ringan dan penerimaan diri yang rendah dan sedang. Terdapat total 26 subjek dalam penelitian ini. Pengambilan data menggunakan skala Severity Measure for Specific Phobia—Adult dari APA dan skala penerimaan diri. Hasil uji menunjukkan tidak ada perbedaan signifikan antara kelompok kontrol dan kelompok eksperimen (p=0,059 (0>0,05) untuk uji Mann-Whitney U. Selanjutnya dilakukan uji Friedman untuk mengetahui perbedaan pada kelompok eksperimen dari sebelum dan sesudah diberi perlakuan dan mengikuti follow-up. Hasil uji menunjukkan terdapat perbedaan signifikan pada kelompok eksperimen sebelum dan sesudah diberi perlakuan, serta setelah mengikuti follow-up (p=0,018, p<0,05). Hal tersebut mengindikasikan bahwa pelatihan self-compassion secara daring dapat dilakukan untuk meningkatkan penerimaan diri pada mahasiswa tahun pertama Fakultas Psikologi Universitas Diponegoro dengan fobia spesifik ringan.
PENGARUH EDIBLE COATING BERBASIS GELATIN-ALGINAT TERHADAP KEMUNDURAN MUTU BAKSO IKAN LELE (Clarias sp.) PADA PENYIMPANAN SUHU RUANG
Authors: Chotimah Khusnul , Dewi Eko Nurcahya , Suharto Slamet 
Published: May 2023

Penggunaan Edible coating yang bersifat antimikroba berpotensi mencegah kontaminasi patogen dan memperbaiki mutu pangan. Tujuan penelitian ini adalah mendapatkan formula edible coating berbasis gelatin-alginat dengan konsentrasi terbaik, dan mengetahui pengaruh aplikasi formula edible coating terhadap umur simpan produk dan mutu bakso ikan setelah dicoating. Bahan yang digunakan yaitu gelatin ikan, alginat dan bakso ikan lele. Metode penelitian yang digunakan bersifat eksperimental laboratories dengan rancangan percobaan Rancangan factorial split plot terbagi oleh waktu. Parameter yang diamati adalah uji viskositas, total fenol, dan uji hedonic, pengamatan visual (lendir), uji TVBN, serta uji TPC. Data dianalisis menggunakan Analisa sidik ragam (ANOVA). Untuk mengetahui perbedaan antar perlakuan, data diuji dengan uji lanjut BNJ. Berdasarkan hasil penelitian dapat disimpulkan bahwa edible coating gelatin-alginat dengan konsentrasi terbaik adalah edible coating gelatin dengan penambahan alginat 1,5% dengan kadar fenol 102,2±0,67, nilai viskositas 14150±753,28 cP dan nilai hedonik dengan selang kepercayaan 6,72<µ<7,04. Aplikasi edible coating gelatin-alginat efektif untuk dapat meningkatkan mutu pada bakso ikan selama penyimpanan selama 24 jam pada suhu ruang dibandingkan dengan kontrol. Hal ini dapat disimpulkan dari nilai organoleptik dengan nilai selang kepercayaan 95% yakni 6,37<µ<6,65. Nilai TVBN dan TPC mengalami penurunan paling rendah yakni 22,21±1,16 mgN% dan 4,61±0,31 log koloni/g. dan penampakan visual (lendir) bakso ikan lele masih lebih baik dibandingkan dengan perlakuan lainnya.
Pengembangan Akses Air Minum di Pedesaan: Penyediaan Air Berbasis Masyarakat untuk Mencapai Akses Air Minum Aman di Banjar Dauh Peken, Bali
Authors: Djaja I Made , Wispriyono Bambang , Aryati Gita Permata , Nurmalasari Nurmalasari , Putri Nanda Marhandhika 
Published: May 2023

AbstrakKemudahan mengakses air bersih yang cukup, merupakan aspek penunjang kesehatan masyarakat yang perlu mendapat perhatian khusus. Makalah ini merupakan laporan berbasis kasus yang bertujuan untuk menggambarkan langkah-langkah penyediaan air minum masyarakat dalam bentuk Stasiun Pengisian Air Minum Umum atau Depot Air Minum Pedesaan (DAMIUP) di Banjar Dauh Peken, Bali. Pemberian DAMIUP merupakan langkah nyata untuk mengembangkan akses air minum dan pengelolaan sumber dayanya di Dauh Peken Banjar, Desa Penarungan, Kecamatan Mengwi, Kabupaten Badung, Bali. Dalam seminggu, pompa DAMIUP dinyalakan 3–4 kali dengan perkiraan masyarakat telah menggunakan 6000–7500 liter air DAMIUP, atau setara dengan 300–350 botol galon. DAMIUP dapat secara signifikan mengurangi risiko kontaminasi dan pengangkutan air dengan mengurangi waktu pengangkutan air dan penggunaan sistem perpipaan. Keterlibatan masyarakat sangat penting dalam mempertahankan sistem. Kedepannya, masyarakat dapat meminta bantuan kepada dinas kesehatan setempat untuk melakukan pemantauan secara berkala guna menjaga dan meningkatkan kualitas air. Abstract The ease of accessing sufficient, clean water is an aspect of supporting public health that requires special attention. This paper is a case-based report aiming to depict the steps on community water provision in the form of Public Water Refilling Station or called Depot Air Minum Pedesaan (DAMIUP) in Banjar Dauh Peken, Bali. The provision of DAMIUP is a concrete step to develop access to drinking water and its resources management in Dauh Peken Banjar, Penarungan Village, Mengwi District, Badung Regency, Bali. In a week, the DAMIUP pump is turned on 3 – 4 times with an estimate that the community has used 6000–7500 liters of DAMIUP water, or the equivalent of 300 – 350 gallon bottles. DAMIUP can significantly reduce the risk of contamination and water transportation by reducing the time to transport water and the usage of piping systems. Community involvement is highly crucial in sustaining the system. In the future, the community can seek assistance from local health authorities to carry out regular monitoring to maintain and improve water quality.
Pelatihan Kuesioner Praskrening Perkembangan Bagi Guru Paud Dan Taman Kanak-Kanak Di Manokwari Papua Barat
Authors: Fabanjo Ivonne Junita , Susantie Niluh Gede , Paisey Feni Mayana , Inyomusi Yunike 
Published: May 2023

Upaya kesehatan anak kesehatan anak harus dilakukan sedini mungkin sejak anak dalam kandungan sampai lima tahun pertama kehidupannya. Proses deteksi dan stimulasi tumbuh kembang menjadi hal penting untuk membentuk generasi penerus yang berkualitas secara fisik, emosional, maupun sosial. Kuesioner Praskrining Perkembangan (KPSP) merupakan salah satu alat deteksi dini yang digunakan di tingkat pelayanan primer. Guru di sekolah merupakan salah satu mitra tenaga kesehatan dalam upaya deteksi dini perkembangan anak. Pentingnya pengetahuan tentang KPSP dan bagaimana cara menggunakannya akan mendorong para guru untuk lebih aktif melakukannya dengan tepat. Metode yang digunakan dalam kegiatan ini adalah pelatihan bagi guru PAUD dan TK yang berada di Kabupaten Manokwari. Sebelum dan sesudah pelatihan dilakukan pengukuran pengetahuan dengan kuesioner tentang KPSP anak. Ketrampilan peserta digunakan lembar observasi peserta pada saat simulasi. Hasil pelatihan terhadap 30 orang guru PAUD dan TK melalui pre-test dan post-test menunjukkan peningkatan pengetahuan 20 orang (93%), hasil penilaian keterampilan peserta selama simulasi 13 orang (43%) dengan kategori mampu dan dengan kategori mahir 17 orang (57%). ABSTRACTChild health efforts should be carried out as early as possible from the child in the womb until the first five years of life. The process of detection and stimulation of growth and development is important to form the next generation of quality physically, emotionally, and socially. The Development Preskrining Questionnaire (KPSP) is one of the early detection tools used at the primary service level. Teachers in schools are one of the partners of health workers in efforts to detect early child development. The importance of knowledge about KPSP and how to use it will encourage teachers to be more active in doing it appropriately. The method used in this activity is training for PAUD and Kindergarten teachers located in Manokwari Regency. Before and after training, knowledge measurements are carried out with questionnaires about children's KPSP. Participants' skills were used as participant observation sheets during the simulation. The results of training of 30 PAUD and Kindergarten teachers through pre-test and post-test showed an increase in knowledge of 20 people (93%), the results of the participants' skill assessment during the simulation of 13 people (43%) with the capable category and with the proficient category of 17 people (57%).
Penguatan Kader Posyandu Dalam Upaya Peningkatan Pelayanan Posyandu Balita di Masa Pandemi Covid 19
Authors: Roza Shelvy Haria , Afrizal Riki 
Published: May 2023

Capaian pelayanan posyandu di wilayah kerja Puskesmas Dadok Tunggul Hitam masih rendah, hal ini juga berdampak pada masa pandemi. Hal ini disebabkan, karena mayoritas penduduk bekerja, selain itu karena pandemi COVID 19 sehingga pelayanan posyandu belum berjalan maksimal. Tujuan kegiatan pengabdian masyarakat ini adalah meningkatkan peran kader posyandu balita dan ibu dalam upaya peningkatan pelayanan posyandu balita di masa pandemi COVID 19. Metode pelaksanaan kegiatan adalah dengan melakukan Focus Group Discussion dengan enam kader di Posyandu Tulip Kelurahan Bungo Pasang untuk mengetahui permasalahan posyandu dan peran kader dalam pengelolaan posyandu, dan memberikan penyuluhan kesehatan mengenai pelayanan dan pengelolaan posyandu di masa pandemi. Penyuluhan dilakukan melalui ceramah dan diskusi tanya jawab. Hasil kegiatan didapatkan bahwa adanya antusias dari kader dalam mengikuti penyuluhan ini, dan terjadinya peningkatan kapasitas kader dalam pengelolaan posyandu. Hal ini terlihat terjadinya peningkatan pengetahuan dan keterampilan kader mengenai pengelolaan posyandu di masa pandemi.