bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANÁLISE DAS RELAÇÕES ESPACIAIS DOS CASOS CONFIRMADOS E ÓBITOS DA COVID-19 NO PERÍODO DE MARÇO A AGOSTO DE 2020 NO ESTADO DE PERNAMBUCO, BRASIL
Authors: Candeia Bruna Araujo , Candeias Ana Lúcia Bezerra , Tavares Junior João Rodrigues 
Published: March 2023

Modelando os dados da COVID-19 e elaborando mapas temáticos, foi possível analisar padrões de comportamento espaço-temporal do novo coronavírus em Pernambuco. Sendo possível identificar: 01- Os maiores números de casos e óbitos estão relacionados aos municípios de maior PIB per capita; 02- A dispersão da doença acompanha as direções da rede principal de rodovias federais; 03- Os mapas temáticos dos municípios agregados aos números de casos e óbitos repercutem na propagação articulada e intensa de padrões em blocos de municípios conectados por rodovias na linha do tempo, vide Serra Talhada, São José de Belmonte, Mirandiba, Salgueiro e Parnamirim; 04- Outros municípios como Santa Maria da Boa Vista e Orocó se apresentam isolados com menos casos, assim como Belém do São Francisco e Carnaubeira da Penha, pequenos blocos isolados com menos casos e óbitos, analogamente a Ibimirim e Custódia; já Águas Belas e Serra Talhada apresentam-se fora da propagação em bloco, os “municípios-ilhas”. Revelando, assim, um comportamento de propagação da doença, de municípios isolados ou articulados em torno e ao longo de eixos viários federais. As BR-104 e 232 assumem influência regional e as estradas estaduais e vicinais podem ter contribuído para maior "capilaridade" da disseminação da COVID-19.
Tamaño de repeticiones CTG no aumentado en la transmisión de un padre con alelo expandido: falsa sospecha de fenómeno de contracción
Authors: Goñi Ros Nuria , Sienes Bailo Paula , González Tarancón Ricardo , Martorell Sampol Loreto , Izquierdo Álvarez Silvia 
Published: March 2023

Resumen

Objetivos
La distrofia miotónica tipo 1, conocida también como enfermedad de Steinert, es un desorden multisistémico crónico, degenerativo e incapacitante de expresividad clínica muy variable provocado por una expansión heredada de manera autosómica dominante de la repetición del triplete citosina-timina-guanina, localizada en la región 3′ no codificante del gen DMPK (19q13.3).

Caso clínico
En este estudio, presentamos el caso de una familia con varias expansiones de la repetición CTG intergeneracionales, con un caso adicional de falsa sospecha de fenómeno de contracción, debido a las limitaciones de la técnica TP-PCR.

Conclusiones
La inestabilidad meiótica de las repeticiones de (CTG)n provoca anticipación genética. De este modo, a lo largo de las sucesivas generaciones, se ha hallado un incremento del tamaño de la mutación DM1 y un fenotipo más severo en los individuos afectados. Aunque es extremadamente infrecuente, en la transmisión de padres a hijos, también puede producirse una disminución en el número de repeticiones CTG, siendo esta más frecuente en la transmisión paterna.
Dynamical analysis of a reaction–diffusion mosquito-borne model in a spatially heterogeneous environment
Authors: Wang Jinliang , Wu Wenjing , Li Chunyang 
Published: March 2023

Abstract
In this article, we formulate and perform a strict analysis of a reaction–diffusion mosquito-borne disease model with total human populations stabilizing at H(x) in a spatially heterogeneous environment. By utilizing some fundamental theories of the dynamical system, we establish the threshold-type results of the model relying on the basic reproduction number. Specifically, we explore the mutual impacts of the spatial heterogeneity and diffusion coefficients on the basic reproduction number and investigate the existence, uniqueness, and global attractivity of the nontrivial steady state by utilizing the arguments of asymptotically autonomous semiflows. For the case that all parameters are independent of space, the global attractivity of the nontrivial steady state is achieved by the Lyapunov function.
Np(V) azide complexes with electroneutral N-donor ligands
Authors: Grigoriev Mikhail S. , Charushnikova Iraida A. , Fedoseev Alexandr M. 
Published: March 2023

Abstract
Two new Np(V) azide complexes with electroneutral N-donor ligands of terpyridine derivatives have been synthesized and structurally characterized: [(NpO2)(Cl-Terpy)(N3)(H2O)] (1) and a centrosymmetric dimer [(NpO2)(EtO-Terpy)(N3)]2·2CH3OH (2). The coordination polyhedra of Np atoms in compounds are pentagonal bipyramids with “yl” oxygen atoms in apical positions. The equatorial plane of the bipyramid in complex 1 is formed by: a nitrogen atom from an anion, three nitrogen atoms from an electroneutral Cl-Terpy ligand and an oxygen atom of a water molecule. The equatorial plane of bipyramids in dimer 2 is formed by five nitrogen atoms: two atoms from two anions [N3]− and three atoms from EtO-Terpy. In compound 1, the anion [N3]− acts as a monodentate ligand, and in compound 2, the anion [N3]− is a bidentate-bridging ligand.
Tenofovir-induced hypophosphatemic osteomalacia: how do bone mineral density, trabecular bone score and proximal hip geometry change with treatment?
Authors: Joseph Aneez , Cherian Kripa Elizabeth , Kapoor Nitin , Paul Thomas V 
Published: March 2023

Summary
Tenofovir-induced osteomalacia secondary to proximal renal tubular dysfunction is not an uncommon complication known to occur. A 46-year-old woman was referred for the evaluation of osteoporosis which was diagnosed elsewhere. She had polyarthralgia, bony pains and proximal muscle weakness of 1 year duration. She was diagnosed to have HIV infection and was on antiretroviral therapy that consisted of tenofovir, lamivudine and efavirenz for the past 12 years. She had attained menopause 5 years back. On examination, she had bone tenderness, proximal myopathy and painful restriction of movement of her lower limbs. Investigations showed features of renal tubular acidosis, hypophosphatemia and raised alkaline phosphatase that were suggestive of osteomalacia. X-ray of the pelvis showed diffuse osteopenia and an MRI of the pelvis done showed multiple insufficiency fractures involving the head of femur on both sides. Following this, her tenofovir-based regimen was changed to abacavir, efavirenz and lamivudine with addition of neutral phosphate supplements and calcitriol. On follow-up after 6 months, she had significant improvement in her symptoms as well as in the bone mineral density at the lumbar spine (33.2%), femoral neck (27.6%), trabecular bone score (13.2%) and reduction in the buckling ratio at the narrow neck (6.3%), inter-trochanteric region (34%) and femoral shaft (28.8%). Tenofovir-induced osteomalacia is encountered in individuals on prolonged treatment with tenofovir. Treatment consists of changing to a non-tenofovir-based regimen, as well as supplementation of phosphate and calcitriol. Treatment results in remarkable improvement in symptoms and most densitometric indices.

Learning points

Tenofovir is a nucleotide reverse transcriptase inhibitor (NRTI) and is a major drug in the treatment of retroviral and hepatitis B infections.

Tenofovir-related hypophosphatemic osteomalacia is related to proximal tubulopathy and is not an uncommon occurrence.

Treatment mandates changing to a non-tenofovir-based regimen with supplementation of neutral phosphate and calcitriol.

Treatment results in a significant improvement in bone mineral density, trabecular bone score and hip geometric parameters.
Describir el funcionamiento de los biobancos a nivel internacional a partir de la NTC-ISO 20387:2020
Authors: Cardenas Suárez Diana Mercy , Torres Amado Jennifer 
Published: March 2023

Dentro de la investigación biomédica, los biobancos se han convertido en un recurso de datos esencial. El uso de material biológico proveniente de múltiples fuentes primarias es una necesidad para los investigadores que buscan generar nuevo conocimiento. De esta necesidad nacen los biobancos, que se definen como repositorios de especímenes biológicos y sus datos asociados, para el fomento de la investigación científica y biomédica.

En Colombia no se cuenta con lineamientos estandarizados para la adecuada implementación de Biobancos, como consecuencia, los centros de investigación puede estar perdiendo beneficios y competitividad, requiriéndose promover el uso de estándares internacionales como la Norma ISO 20387, la cual brinda lineamientos para implementar requisitos generales para la competencia, la imparcialidad y la operación coherente de biobancos. Acorde a los resultados de la investigación, no se identifican en el Colombia biobancos certificados en esta norma.
El objetivo fundamental de este artículo de reflexión es indagar y conocer la estructura organizativa de biobancos actuales a través de un análisis de los elementos estructurales que los constituyen frente a los requisitos definidos en la norma ISO 20387:2020, con el fin de describir su funcionamiento a nivel internacional contribuyendo al desarrollo competitivo de los biobancos nacionales.
Para lograr este objetivo se realizó una primera etapa de revisión de literatura, identificando 30 artículos referentes, se continuó con una exploración de 20 biobancos a los cuales en una tercera etapa se les realizó un análisis de cumplimento de los requisitos de la norma, finalmente se trianguló la información para describir los aspectos de estructura, recursos, generalidades, procesos y sistemas de gestión de la calidad, concluyendo con su viabilidad y beneficios de implementación
Covid-19 en la población indígena del Cauca, visibilidad de la vulnerabilidad estructural como un reto para la gestión en salud
Authors: Rodriguez-Rojas Yuber Liliana 
Published: March 2023

La propagación del COVID-19 generó una serie de retos para los países, no solo a nivel de la atención en los servicios de salud por el aumento de número de casos, lo que implicó aumento de las instalaciones, equipos y profesionales de la salud, sino las múltiples manifestaciones clínicas que tenía el desarrollo de la enfermedad. El objetivo de este artículo es reconocer el comportamiento del Covid-19 y determinar si los determinantes estructurales como es el estrato socioeconómico, afiliación al sistema de seguridad se relacionan con la presencia y evolución de la enfermedad. Para ello, se hizo un análisis de los casos reportados al Sistema Nacional de Vigilancia de Salud Pública de la población indígena del Cauca-Colombia, determinando la frecuencia de presentación de la enfermedad y una posible definición de riesgo de mortalidad (OR). Los resultados evidencian que los indígenas que se encuentran en el sistema de seguridad social subsidiada (OR=19,5 p=0,000) y en un estrato socioeconómico 1 (OR=17,9 p=0,052), tienen mayor probabilidad de tener Covid-19. Se evidencia que determinantes estructurales se asocian positivamente con la posibilidad de tener Covid-19 en los pueblos indígenas del Cauca.
Green supplier selection problems with data scaling and production frontier estimations in a DEA model
Authors: Dobos Imre , Vörösmarty Gyöngyi 
Published: March 2023

AbstractConsidering ecological issues in supplier evaluation and management alongside business considerations is getting more recognition among firms. Data envelopment analysis (DEA) is one of those methods, which is frequently suggested by the literature to support management decisions. However, the data requirements of the method should be an important consideration. The literature often addresses the issue of desirable outputs and undesirable input as an important data related problem in case of the ecological use of DEA. This paper will present a new solution to manage these data problems along with connecting the evaluation of management criteria, environmental criteria and total cost aspects. The proposed environmental supplier selection problem is an extension of a former paper. The new model examines the effect of inventory related costs, such as EOQ costs of inventory holding or ordering costs on the selected supplier, extended with newly introduced scaled values of input and output indicators. The usage of scaled values is motivated by the problem of invariance to data alteration. In addition to the uncertainty of the data, the paper looks for a functional relationship between the input and output criterion values and the efficiency that can be assigned to them using DEA.
Methodology of recreation in the structure of the educational space
Authors: Zaytzev Viacheslav , Iermakov Sergii , Hagner- Derengowska Magdalena 
Published: March 2023

Background and Study Aim. The aim of the study is to present the methodological aspects of health, healthy lifestyle and recreation of students in higher educational institutions.
Materials and Methods. Sources of information are publications in domestic literature. A total of 37 publications were selected.
Results. The historical moments of recreation and the conceptual definition of recreational activities are presented. Certain characteristics of types and functions of recreation, recreational system, recreational zoning, placement and correlation of active recreation facilities are given. An important factor in conducting recreational activities is: the desire of students; high professional level of doctors, rehabilitologists, instructors, methodologists of medical physical culture.
Conclusions. Recreation is a collective concept and it reflects mainly active and passive recreation of a person outside of labor, educational, scientific and other activities. Such activities are aimed at the formation, restoration, strengthening and preservation of health. The most favorable environment are sanatorium and health-improving institutions.
Keywords: higher educational institution, student, teacher, recreation, active recreation, passive recreation.
Recreational resources – the basis of human active recreation
Authors: Zaytzev Viacheslav , Iermakov Sergii , Manucharyan Svitlana 
Published: March 2023

Background and Study Aim. The aim of the work is to analyze the theoretical aspects of recreational resources in Ukraine and their use in practice.
Materials and Methods. Sources of information are publications in domestic literature. A total of 20 publications were selected.
Results. Theoretical aspects of the recreational resources of Ukraine, their classification and scoring (biomedical, psychological, technological) are presented. A particular difficulty in assessing recreational resources lies in the fact that they should be considered from the perspective of recreation organizers and vacationers. The importance of recreational relax for a person (student) in sanatorium-resort conditions is shown. Therefore, the curators have two main tasks: medical care for patients (secondary prevention) and recreation.
Conclusions. One of the foundations of active and passive recreation are recreational resources. Recreational resources are a set of natural and artificial objects and phenomena that can be used for active and passive recreation, tourism and treatment. Therefore, it is necessary to focus on resource centers of the sanatorium and medical type and historical and cultural resources.
ANALISIS KEMAMPUAN MENYUSUN LAPORAN KEUANGAN, KEMAMPUAN MANAJERIAL, JIWA KEWIRAUSAHAAN DAN MOTIVASI SEBAGAI FAKTOR PENENTU KINERJA OPERASIONAL
Authors: Wahid Nisa Noor 
Published: March 2023

Pelaku usaha meubel di Kota Tasikmalaya saat ini membutuhkan peningkatan kinerja agar mampu meningkatkan kualitas dan kuantitas untuk bersaing dengan produk impor terlebih akibat adanya era pasar bebas ASEAN. Sehingga dibutuhkan penelitian untuk mengetahui penyebab dominan untuk meningkatkan kinerja operasionalnya. Tujuan penelitian ini adalah untuk mengetahui pengaruh kemampuan menyusun laporan keuangan, kemampuan manajerial, motivasi dan jiwa kewirausahaan terhadap kinerja operasional. Sehingga dalam jangka waktu pendek manajemen akan mengetahui bagaimana manfaat-manfaat yang diperoleh untuk meningkatkan kinerja usahanya. Metode yang digunakan yaitu melalui penyebaran kuesioner kepada 50 orang pelaku UKM Meubel di Kota Tasikmalaya dan dianalisis menggunakan regresi berganda. Hasil Penelitian menunjukkan bahwa kemampuan menyusun laporan keuangan dan motivasi berpengaruh positif terhadap kinerja operasional, sedangkan kemampuan manajerial dan jiwa kewirausahaan tidak berpengaruh terhadap kinerja operasional pelaku UKM meubel di Kota Tasikmalaya. Dengan demikian maka diharapkan para pelaku usaha meubel dapat menyusun laporan keuangan dengan baik serta meningkatkan motivasi agar dapat memiliki kinerja usaha yang lebih baik.
Pengaruh Corporate Governance, Kompetisi dan Karakteristik Perusahaan Terhadap Pengungkapan Risiko Perusahaan
Authors: Muslih Muhamad , Mulyaningtyas Cahya Tri 
Published: March 2023

Abstract. The study aims to determine the impact of corporate governance, competition and corporate characteristics on corporate risk disclosure in consumer goods sector manufacturing industry listed on the Indonesia Stock Exchange period 2013-2017. The population in this study is consumer good sector manufacturing industry listed on the Indonesia Stock Exchange period 2013-2017. The sampling technique used was purposive sampling and obtained 21 companies with a research period of 5 years. The analytical method used in this study is panel data regression analysis using E-views 10 Student Version software. The results showed that simultaneously corporate governance, competition and corporate characteristics had a significant effect on corporate risk disclosure. Partially, Independent board of commisioners, quality of external auditors, firm size, profitability had no significant effect on corporate risk disclosure. Meanwhile, competition has a positive significant effect on corporate risk disclosure.Keywords: Corporate Governance; Competition; Corporate Characteristics; Corporate Risk DisclosureAbstrak. Penelitian ini bertujuan untuk mengetahui pengaruh corporate governance, kompetisi dan karakteristik perusahaan terhadap pengungkapan risiko perusahaan pada industri manufaktur sektor barang konsumsi yang terdaftar di Bursa Efek Indonesia tahun 2013-2017. Populasi dalam penelitian ini adalah industri manufaktur sektor barang konsumsi yang terdaftar di Bursa Efek Indonesia tahun 2013-2017. Teknik pengambilan sampel yaitu purposive sampling dan diperoleh 21 perusahaan dengan periode penelitian selama 5 tahun. Metode analisis data dalam yang digunakan adalah analisis regresi data panel dengan menggunakan software E-views 10 Student Version. Hasil penelitian menunjukkan bahwa secara simultan corporate governance, kompetisi dan karakteristik perusahaan berpengaruh signifikan terhadap pengungkapan risiko perusahaan. Secara parsial, dewan komisaris independen, kualitas auditor eksternal, ukuran perusahaan dan profitabilitas berpengaruh tidak signifikan terhadap pengungkapan risiko perusahaan. Sedangkan, kompetisi berpengaruh signifikan dengan arah positif terhadap pengungkapan risiko perusahaan.Kata Kunci: Corporate Governance; Kompetisi; Karateristik Perusahaan; Pengungkapan Risiko Perusahaan
Kecurangan Akademis Mahasiswa: Kenapa Terjadi dan Apa yang Harus Dilakukan?
Authors: Fontanella Amy , Sukartini Sukartini , Chandra Novrina , Sriyunianti Fera 
Published: March 2023

This study investigates determinants of academic dishonesty. Using the fraud triangle concept, this study examined the effect of pressure, opportunity and rationalizations towards academic dishonesty. This research conducted on Accounting Department of Padang State Politechnic (PNP). This study also analyzes the efforts made by PNP to minimize academic dishonesty. Using a sample of 436 students, this study found that pressure, opportunity and rationalization have a positive effect on academic dishonesty. We also found an opportunity to cheat strengthens the effect of academic pressure on academic dishonesty. The results of interviews and focus group discussions indicate the commitment of PNP to instill honesty values for students through various ways such as determination and dissemination rules related to academic dishonesty, contract agreements related to fraud rules and the implementation of severe sanctions for the perpetrators of fraud. However, a comprehensive and systematic approach is needed to make honesty as a value of department. Penelitian ini bertujuan menginvestigasi determinan perilaku kecurangan akademis mahasiswa. Dengan menggunakan konsep fraud triangle, penelitian ini menguji pengaruh tekanan untuk melakukan kecurangan, kesempatan berbuat curang dan rasionalisasi dalam melakukan kecurangan terhadap perilaku kecurangan mahasiswa. Penelitian ini dilakukan pada Jurusan Akuntansi Politeknik Negeri Padang (PNP. Penelitian ini juga menganalisis upaya-upaya yang telah dilakukan PNP untuk meminimalisir tingkat kecurangan. Dengan menggunakan sampel 436 mahasiswa, penelitian ini menemukan bahwa faktor tekanan, kesempatan dan rasionalisasi berpengaruh positif terhadap perilaku kecurangan mahasiswa. Penelitian ini juga menemukan kesempatan untuk berbuat curang memperkuat pengaruh tekanan akademis terhadap kecurangan akademis. Hasil wawancara dan focus group discussion menunjukkan komitmen PNP untuk menanamkan nilai-nilai kejujuran bagi mahasiswa melalui berbagai cara seperti penetapan dan sosialisasi aturan terkait kecurangan akademis, penandatangan kontrak kesepakatan terkait aturan kecurangan serta penerapan sanksi yang berat bagi pelaku kecurangan. Namun masih perlu dilakukan pendekatan yang komprehemsif, sistematis dan melibatkan seluruh komponen untuk menjadikan kejujuran sebagai value Jurusan.
Perceived Risk, Perceived Functional Benefit, dan Kepuasan sebagai Penentu Intensi Berkelanjutan Wajib Pajak Menggunakan e-filing
Authors: Mangoting Yenni 
Published: March 2023

Penelitian bertujuan untuk menguji dampak perceived functional benefit sebagai mediasi dalam pengaruh penggunaan e-filing terhadap kepuasan dan intensi berkelanjutan wajib pajak. Pengujian moderasi juga dilakukan untuk mengetahui pengaruh kuat dan lemahnya perceived risk dalam hubungan e-filing dan kepuasan wajib pajak. Responden penelitian adalah wajib pajak orang pribadi yang telah menggunakan e-filing. Jumlah responden penelitian adalah 220 wajib pajak orang pribadi. Alat menguji hipotesis menggunakan Wrap-PLS. Hasil penelitian menunjukkan bahwa semua variabel yang diuji secara langsung yaitu e-filing, perceived functional benefit menunjukkn pengaruh sigfnifikan terhadap kepuasan dan intensi keberlanjutan wajib pajak menggunakan e-filing dalam jangka panjang. Uji variabel mediasi menunjukkan bahwa perceived functional benefit dan kepuasan wajib pajak dapat memediasi. Artinya, pengunaan e-filing yang makin tinggi dapat meningkatkan manfaat yang dirasakan wajib pajak sehingga meningkatkan niat berkelanjutan wajib pajak menggunakan e-filing. Faktor moderator, yaitu perceived risk tidak menunjukkan pengaruh signifikan untuk menguatkan atau melemahkan hubungan antara e-filing dan kepuasan wajib pajak. Penelitian menegaskan bahwa pemerintah perlu meningkatkan kapasitas sistem online tidak hanya memfokuskan pada kemudahan penggunaan e-filing, namun juga manfaat fungsional yang diharapkan yaitu, efisiensi biaya dan waktu dan efektivitas dalam menyelesaikan kewajiban perpajakan, dan kemudahan aksesibilitas.