bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of Ag-CNTs and Ag-Graphene nanocomposite and their combination with MnO2 bath deposition for flexible supercapacitor development.
Authors:   , Keawploy Norawich 
Published: September 2023

Nowadays, researchers have made great efforts on the development of flexible and light weight energy storage devices for their practical applications and the advancement of modern electronic devices. Owing to the promising feathers of high specific power, high rate capability, and long-term cycling life, the supercapacitors (SCs) are considered as highly suitable for various flexible applications. In general, the carbon-based nanomaterials such as carbon nanotubes and graphene nanosheets, exhibit good supercapacitor performance. Manganese dioxide (MnO2) are widely studied for pseudocapacitors owing to their high specific capacitance, high power, and energy density. Thus, MnO2 was applied to increase the supercapacitor performance of carbon materials. However, most of the reported SCs are bulk, heavy, and non-flexible, which are not suitable for wearable energy technology. To overcome these challenges, flexible supercapacitors (FSCs) are developed to meet the wearable electronics. The cotton cloth materials are widely considered for flexible substrates due to inexpensive natural fiber, highly hydrophilic and light weight. In this work, the conductive cotton was successfully prepared by the screen-printing method using the developed ink. The designed textile ink and silver powder mixture demonstrates an outstanding conductivity. The prepared conductive cotton reached a low resistance of less than 15 ohm/cm2. Furthermore, the supercapacitor electrodes were also fabricated by mixing the active materials (CNT, and graphene) into the developed ink. Among these different carbon electrodes, the CNT electrodes show superior electrochemical performance (78.49 mF/cm2 at 0.1 mA/cm2). To further enhance the specific capacitance, the MnO2 was coated on the electrodes by chemical bath deposition (CBD) using potassium permanganate and sulfuric acid solution. The specific capacitance of as high as 741.83 mF/cm2 at 0.1 mA/cm2 was achieved. Finally, the flexible supercapacitor device was also successfully fabricated, which exhibited a high specific areal capacitance of 677.12 mF/cm2 at 0.0125 mA/cm2 for CNT electrodes. The flexible device also shows excellent rate performance and cyclic stability with capacitance retention of 80% for 3000 cycles, demonstrating that advanced flexible energy storage devices can be achieved.
The efficacy of vitamin c oral supplement on wound healing after tooth extraction
Authors:   , Pisalsitsakul Nanthanut 
Published: September 2023

Objectives: The purpose of this study was to evaluate the effect and proper dosage of oral vitamin C supplement on post-extraction wound healing.

Methods: This study was a split mouth, double-blind, randomized-controlled clinical trial of 42 patients who underwent symmetric bilateral non-infected premolars extraction. The patients were randomly divided into 3 groups (14 patients for each group); 1.placebo vs vitamin C 600 mg/d, 2.placebo vs vitamin C 1,500 mg/d and 3.vitamin C 600 mg/d vs vitamin C 1,500 mg/d. Each group was prescribed placebo and/or vitamin C three times a day for 10 days after each tooth extraction. The assessment of the wound was performed on day 0, 7 and 21 then then the other side extraction was performed with the same protocol. Size of the extraction wound in bucco-lingual width, mesio-distal width, depth and 1% toluidine blue stained were collected by two examiners. Pain score and high vitamin C-containing diets were recorded by each patient on the first three days and seven days, respectively.

Results: The percentage reduction of the extraction wound size in mesiodistal dimension between day 0 and day 7 of teeth receiving vitamin C 600 mg daily was more than that in placebo (P < 0.05). Pain scores on day 1-3 after tooth extraction of teeth receiving vitamin C 600 mg daily was significantly lower than the placebo side (P < 0.05).

Conclusion: Taking oral vitamin C 600 mg/d for 10 days after tooth extraction tended to promote extraction wound healing and reduced post-operative pain.
Association between clinical signs and quality of life in Thai patients with oral lichen planus
Authors:   , Yiemstan Sasirin 
Published: September 2023

Subjective patient’s symptoms and oral health-related quality of life (OHRQoL) were recommended to be involved in oral lichen planus (OLP) studies. Objectives: to evaluate 1) the association between OLP clinical signs and OHRQoL as well as pain perception. 2) the association between OLP pain and OHRQoL. Methods: Sixty-nine OLP or oral lichenoid drug reaction (OLDR) Thai patients were recruited. Data were collected through personal interview with the Numeric Rating Scale (NRS) and Thai version of Oral Impacts on Daily Performance (OIDP) index. OLP signs were examined in aspects of localization, type and clinical severity according to the Thongprasom sign scoring system. Results: 1) there was statistically significant association between OLP clinical severity and the intensity of oral impacts (Spearman’s correlation (rs) = 0.490, p < 0.001) and with OLP pain (rs = 0.298, p = 0.013). The intensity of OLP impacts and pain intensities were increased along with OLP clinical severity, except for the clinical score 1. The ulcerative OLP lesions equivalent to clinical score 4 and 5 were the most painful symptom and had substantial impacts on OHRQoL. Presence of OLP at soft palate had considerable worsened OHRQoL. 2) there was statistically significant association between OLP pain and the intensity of oral impacts (rs= 0.400, p = 0.001). Conclusion: The results showed the OHRQoL measure would valid against OLP clinical measure. As the discrepancy based on its measurement, using merely OLP clinical indicators were insufficient. OHRQoL measures could complement OLP clinical measures.
High magnification polymeric lens for smartphone microscope
Authors:   , Jaikeandee Wisansaya 
Published: September 2023

In this work, we present a facile method for fabrication of plano-convex lenses, using high reflective optical polymer (Polydimethylsiloxane, Sylgard 184 by Dow Corning, n ~1.42 and Norland Optical adhesive 61, NOA61 by Norland Products, ~1.56) under the confined sessile drop technique. The confined sessile drop technique is a facile method and an adjustable lens geometry through controlled the weight of liquid polymer on the lens substrate, as PMMA circular disk and Sylgard circular disk, with different diameter (2.5-6.0 mm). The liquid polymer was gradually spread and radially over the surface of the lens substrate, and resistance to spreading of liquid by a sharp edge under the gravitational force and interfacial surface tension to form spherical cap with smooth surface. When the use of the weight of liquid polymer increased, the deformation of the lens observed due to affect the gravitational force. The fabricated lenses, as Sylgard 184 plano-convex lens and NOA 61 plano-convex lens, provides the magnification up to 51.0X and 88.3X, respectively. In addition, the imaging quality of the fabricated lenses was characterized using USAF 1951 target. The fabricated plano-convex lenses which could be used to convert a smartphone to a smartphone microscope to taken the small objects that cannot see by naked eye. Due to high refractive index of NOA 61 plano-convex lens, it can be utilized as design of low cost SPR sensors under Kretschmann surface plasmon sensors configuration through deposited with 50 nm-Au film on rough surface as base of NOA 61 plano-convex lenses.
Effects of sulodexide in the prevention of peritoneal membrane changes in continuous ambulatory peritoneal dialysis patients
Authors:   , Ditsawanon Panida 
Published: September 2023

The objective of this placebo-controlled clinical study is to determine the effect of sulodexide for the prevention of peritoneal membrane change in PD patients by evaluating dialysate biomarkers of peritoneal membrane change, phenotypes of peritoneal mesothelial cells, peritoneal membrane transports and safety. A total of 66 patients were included in this randomized control trial study. Patients were randomly assigned to receive either 50 mg of sulodexide or placebo by oral 2 times daily. PET was performed to evaluate peritoneal transport function. Dialysate CA125, IL-6 and VEGF concentration were also measured at baseline and after treatment by ELISA. Peritoneal mesothelial cell culture from dialysate effluent was done to evaluate EMT.

Overall, 61 patients completed the 3-month study. After the treatment period, there was a significantly lower D/P creatinine in the sulodexide group than in the placebo group (p-value = 0.04). However, no difference in D/D0 glucose was observed between two groups. For ultrafiltration volume, there was a significantly higher volume in the sulodexide group when compared to the placebo group (p-value = 0.01). Patients in the sulodexide group had no difference change from baseline in CA125 concentration while there was a significantly lower CA125 level in the placebo group (p-value = 0.03). However, no significant difference in CA125 was found between the two groups. For IL-6 , a significantly higher level was found within the placebo group after the treatment period (p-value < 0.01) while there was no difference change within the sulodexide group. When compared between groups, a significantly higher IL-6 level was found in the placebo group than those in the sulodexide group (p-value = 0.03). No difference was observed for VEGF changes both within and between two groups of patients. In conclusion from overall results in this study, the administration of sulodexide has a potentially beneficial effect in the prevention of peritoneal membrane damage in CAPD patients. Sulodexide may be used to slow the progression of peritoneal membrane change.
Phytochemicals with α-glucosidase inhibitory activity from cissus javana, dendrobium christyanum, gastrochilus bellinus and huberantha jenkinsii
Authors:   , San Htoo 
Published: September 2023

Phytochemical investigations of Cissus javana DC., Dendrobium christyanum Rchb. f., Gastrochilus bellinus Rchb. f. Kuntze and Huberantha jenkinsii (Hook. f. & Thomson) Chaowasku led to the isolation of twenty-seven compounds, six of which were new naturally occurring compounds. From Cissus javana, three known compounds were isolated, including bergenin, stigmast-4-en-3-one, and β-sitosterol. From Dendrobium christyanum, thirteen known compounds were identified, namely, n-eicosyl trans-ferulate, n-docosyl 4-hydroxy-trans-cinnamate, 4,5-dihydroxy-2-methoxy-9,10-dihydrophenanthrene, moscatilin, aloifol I, gigantol, batatasin III, dendrosinen B, coniferyl aldehyde, methyl haematommate, atraric acid, vanillin and diorcinolic acid. From Gastrochilus bellinus, four new compounds, comprising three phenanthropyrans and a phenanthrene derivative, were isolated and structurally characterized. From Huberantha jenkinsii, two new alkaloids of 8-oxoprotoberberine type were isolated along with five known compounds including mangiferin, allantoin, oxylopinine, N-trans-feruloyl tyramine and N-trans-p-coumaroyl tyramine. The structures of these compounds were determined by UV, IR, MS and NMR spectroscopic methods, and comparison of the data with literature values. Methyl haematommate (IC50 18.7 ± 2.1 µM), n-docosyl 4-hydroxy-trans-cinnamate (IC50 4.6 ± 0.2 µM), N-trans-feruloyl tyramine (IC50 30.6 ± 2.9 µM) and N-trans-p-coumaroyl tyramine (IC50 0.6 ± 0.1 µM) showed potent α-glucosidase inhibitory activity in comparison with the drug acarbose (IC50 724.7 ± 46 µM). N-Docosyl 4-hydroxy-trans-cinnamate at 0.212 mM also displayed 31.6 ± 4.4 %. enhancement of glucose uptake in L6 cells. Mangiferin showed moderate α-glucosidase inhibition (IC50 253.6 ± 14.2 µM) and recognizable cellular glucose uptake stimulatory activity (208.1 ± 10.7% enhancement at a concentration of 0.237 mM) as compared with insulin (146.6 ± 35.8 % at a concentration of 500 nM).
Cytotoxic effects of mansonone G and ethoxy mansonone G from mansonia gagei drumm in non-small cell lung cancer
Authors:   , Wannachote Arachawipa 
Published: September 2023

Mansonones are naphthoquinone-containing compounds extracted from the heartwood of Mansonia gagei. Several studies have reported that mansonones have various pharmacological activities such as antibacterial, antifungal, antioxidant, antiestrogenic, antiadipogenic and anticancer effects. A previous study reported that ether analogues of mansonone G (MG), a major compound isolated from Mansonia gagei Drumm, displayed higher antibacterial and antiadipogenic activities than parent MG. However, the anticancer activities of MG and ethoxy MG (EMG) on lung cancer cells have never been investigated. This study aimed to determine cytotoxic activities of MG and EMG and the underlying mechanism(s) in two non-small cell lung cancer cell lines, EGFR wild-type A549 cells and EGFR mutant H1975 cells. The present study demonstrated that MG and EMG significantly inhibited the viability of A549 and H1975 cells in a concentration dependent manner. It should be noted that EMG displayed higher cytotoxicity than MG in both A549 and H1975 cells. Notably, EMG was more toxic to NSCLC cells than PCS201-010 normal cells. Mechanistic studies demonstrated that EMG induced cell cycle arrest at G1 phase in A549 cells but did not induce cell cycle arrest at any phase of cell cycle in H1975 cells. Additionally, EMG induced apoptosis through ROS generation in both A549 and H1975 cells and this effect was abolished by N-acetyl cysteine (NAC). Western blotting revealed that EMG downregulated the expression of Bcl-XL and Bcl-2 and upregulated the expression of BAK and BAX in both A549 and H1975 cells. EMG activated the phosphorylation of ERK1/2 and AKT in A549 cells whereas it inhibited the phosphorylation of ERK1/2 and AKT in H1975 cells. Taken together, the results of this study suggest that the cytotoxicity of EMG is mediated via induction of cell cycle arrest and apoptosis, generation of ROS and modulation of PI3K/AKT and MAPK/ERK signaling pathways in NSCLC cells. These results suggest that EMG is a promising anticancer agent for lung cancer.
Association between NAT2 polymorphisms and anti-tuberculosis drug-induced liver injury in Myanmar patients in Thailand
Authors:   , Thaw Khin 
Published: September 2023

The aims of this study were to determine the N-acetyl transferase 2 (NAT2) genetic distribution of Myanmar tuberculosis (TB) patients and evaluate the association of NAT2 polymorphisms and antituberculosis drug-induced liver injury (AT-DILI) in Myanmar patients. A case-control study was conducted in adult Myanmar TB patients at Samut Sakorn Hospital. Fifty-four patients who completed anti-TB treatment without liver injury (controls) and five patients with AT-DILI during their anti-TB treatment (cases) were enrolled. Patients’ baseline characteristics, anti-TB doses, and liver enzyme levels were collected from the hospital’s record. Blood samples were collected and four NAT2 SNPs, rs1041983, rs1799929, rs1799930, and rs1799931, were genotyped using allele-specific polymerase chain reaction (AS-PCR). In this study, all patients received the standard anti-TB regimen with anti-TB doses in World Health Organization (WHO) recommended dose range. Baseline characteristics of cases and controls were not different. NAT2 rs1041983 was highly found in all patients (56%), while cases had higher NAT2 rs1799929 frequency than control (50% vs 10%). The most common allele was NAT2*6A, and the most common genotype was NAT2*4/*7B. Forty-seven percent (n=28) were slow acetylators, while 44% (n=26) were intermediate acetylators. The phenotype distribution in this study is in concordance with Thai and Indonesian studies. There was no association of non-genetic factors and AT-DILI. NAT2 rs1799929 (CT and TT genotypes) showed higher risk to get liver injury than CC genotypes (OR= 19.2865, 95% C.I =1.751-212.417, p = 0.016 and OR = 22.50, 95% C.I = 1.001– 505.846, p = 0.005, respectively). However, there was no association between NAT2 genotype and phenotype and AT-DILI. When stratified patients according to their liver enzyme levels to normal and elevated levels, CT genotype of NAT2 rs1799929 was highly found in patients with elevated AST levels (OR=4.625, 95% C.I=1.078-19.840, p = 0.039). In addition, the highest AST and ALT levels were found in slow acetylators with NAT2*5B/*5B. Multiple linear regression analysis showed that NAT2 SNPs rs1799929, isoniazid dose, and age significantly associated with AST levels (B=49.334, p < 0.001, B=22.241, p=0.007 and B=1.991, p=0.025 respectively). These factors can describe 35% of AST level variation. Furthermore, NAT2 phenotype, isoniazid dose, and age also explained 22% of AST level variation (B=23.781, p=0.038, B=22.003, p=0.016 and B=2.581, p=0.008 respectively). In addition, NAT2 SNPs rs1799929 also exhibited 22% of ALT level variation (B=85.944, p < 0.001). To summarize, this study demonstrated a strong influence of NAT2 rs1799929 on AT-DILI and elevated liver enzymes in Myanmar patients receiving anti-TB treatment. As the NAT2 phenotype distribution of Myanmar patients is similar to the Thai population, this study supports the use of Thai TB guidelines in anti-TB adverse drug reaction monitoring for Myanmar TB patients in Thailand.
Exploring and analysing thailand’s potential new legislation on mandatory human rights due diligence for private sectors
Authors:   , Masee Kritsakorn 
Published: September 2023

This Thesis focuses on a study of potential enforcement of the Legislation on mandatory Human Rights Due Diligence (HRDD) for private sectors operating a business in Thailand in order to safeguard human rights, as recognised in the international human rights laws and national laws, in their value chain within the consideration of the United Nations on Guiding Principles on Business and Human Rights (UNGPs) as well as Thailand’s National Action Plan on Business and Human Rights Phase I (2019-2022). With new corporate governance regime and under emerging concept of due diligence requirements, private sectors subject to this mandatory HRDD Legislation is expected to Protect, Respect, and Remedy the UNGPs, by identifying, preventing adverse impacts on human rights due to business-related human rights abuse and mitigating and accounting for human rights violation. This Thesis illustrates emerging concepts of increased corporate responsibility to address risk to people along their business activities. Further, it discusses policy and legal developments on this type of Legislation by inspecting and analysing existing and potential law of mandatory human rights due diligence in some of the European Union’s Member States as they tend to influence standards of protection and strongly uphold human rights. The Thesis will provide an analysis and a proposal on a body of this law to be enforced in Thailand by identifying characteristics of this law, scope of application, remedial measure, and oversight body. It also extends to analytically address functional and institutional challenges and impacts on relevant stakeholders: rightsholders, private sectors, and Civil Society Organisations (CSOs). With the inclusion of all stakeholders, this potential enforcment of the Legislation could help drive and create an equal, strengthened, and sustainable society, and step forward to sustainable growth altogether.
Legal analysis on bankability of hydro floating solar project in Thailand
Authors:   , Aramtiantamrong Natdanai 
Published: September 2023

In comparison to other types of renewable energy projects, hydro floating solar projects are more complicated as public water resources are used as the location of the project but the electricity is generated from solar power. Accordingly, it is unclear whether the operation of the project falls within the definition of water use that is subject to the Water Resources Act B.E.2561(2018) or not. Several interpretations on the definition of water use in Section 4 of this Act may cause challenges in the bankability of the project. In order to fund the project, the project company generally relies on the loan from financial institutions. The presence of uncertainty in the rights that the project company triggers the problem in the bankability of the project. This thesis will address the criteria that the financial institutions take into consideration, analyze the laws in Thailand that are relevant to the project and compare the law regulating public water resources in Thailand with those in Japan and Australia. Ultimately, the recommendation will be provided to facilitate the bankability of hydro floating solar project in Thailand.
Structural deviation of hydrogenated graphene and multi-layer graphene under high pressure
Authors:   , Pakornchote Teerachote 
Published: September 2023

Graphene, a layer of graphite, has marvelous properties that can enhance the performance of its composite materials. To broaden the capability of its applications, the adatoms are introduced onto graphene to create such distinguish property. Hydrogenated graphene is a hydrogen deposition on graphene forming sp3-hybridization between carbon and hydrogen atoms and deviating the structure of graphene. Partial hydrogenation induces the energy gap and the magnetization of graphene which opens the door to many applications, e.g. semiconducting and spintronic devices. The properties of hydrogenated graphene can be tuned by either plasma bombarding or thermal annealing to raise or reduce, respectively, the number of hydrogen atoms on a graphene surface. Therefore, the hydrogen concentration plays a central role in tunable properties and phase stability of hydrogenated graphene. In this thesis, we studied the phase stability and the phase transition pathway of hydrogenated single-layer graphene and hydrogenated bilayer graphene on theoretical and experimental bases. In the theoretical part, the formation energies of the hydrogenated graphenes with various hydrogen concentrations were obtained using density functional theory (DFT). The phase stabilities are portrayed by the convex hull which is based on the thermodynamic principle. Most of the phases in this study are not energetically favorable, while some of the phases can be stabilized by compressive strain. However, many of them are still dynamically stable. The vibrational analysis was performed to show the fingerprint of possible Raman and infrared (IR) spectrum for guiding the experiment. In the experimental part, the highly hydrogenated graphene was synthesized using laser-heating at high pressure. As a result, the hydrogenation could occur more when the sample was compressed at a higher pressure in the hydrogen environment presenting the hydrogenation pathway toward fully hydrogenated graphene. We also model the possible slippery of graphene from its substrate and show the possible hole-doping of hydrogenated graphene at high pressure.