bluuebunny/crossref_metadata_2025_split huggingface dataset:
Difference in determinants of ICU admission and death among COVID-19 hospitalized patients in two epidemic waves in Portugal: possible impact of healthcare burden and hospital bed occupancy on clinical management and outcomes, March–December 2020
Authors: Ricoca Peixoto Vasco , Vieira André , Aguiar Pedro , Carvalho Carlos , Thomas Daniel , Sousa Paulo , Nunes Carla , Abrantes Alexandre 
Published: June 2023

AimIdentify factors associated with COVID-19 intensive care unit (ICU) admission and death among hospitalized cases in Portugal, and variations from the first to the second wave in Portugal, March–December 2020.IntroductionDeterminants of ICU admission and death for COVID-19 need further understanding and may change over time. We used hospital discharge data (ICD-10 diagnosis-related groups) to identify factors associated with COVID-19 outcomes in two epidemic periods with different hospital burdens to inform policy and practice.MethodsWe conducted a retrospective cohort study including all hospitalized cases of laboratory-confirmed COVID-19 in the Portuguese NHS hospitals, discharged from March to December 2020. We calculated sex, age, comorbidities, attack rates by period, and calculated adjusted relative risks (aRR) for the outcomes of admission to ICU and death, using Poisson regressions. We tested effect modification between two distinct pandemic periods (March–September/October–December) with lower and higher hospital burden, in other determinants.ResultsOf 18,105 COVID-19 hospitalized cases, 10.22% were admitted to the ICU and 20.28% died in hospital before discharge. Being aged 60–69 years (when compared with those aged 0–49) was the strongest independent risk factor for ICU admission (aRR 1.91, 95%CI 1.62–2.26). Unlike ICU admission, risk of death increased continuously with age and in the presence of specific comorbidities. Overall, the probability of ICU admission was reduced in the second period but the risk of death did not change. Risk factors for ICU admission and death differed by epidemic period. Testing interactions, in the period with high hospital burden, those aged 80–89, women, and those with specific comorbidities had a significantly lower aRR for ICU admission. Risk of death increased in the second period for those with dementia and diabetes.Discussion and conclusionsThe probability of ICU admission was reduced in the second period. Different patient profiles were identified for ICU and deaths among COVID-19-hospitalized patients in different pandemic periods with lower and higher hospital burden, possibly implying changes in clinical practice, priority setting, or clinical presentation that should be further investigated and discussed considering impacts of higher burden on services in health outcomes, to inform preparedness, healthcare workforce planning, and pandemic prevention measures.
Change in circulating klotho in response to weight loss, with and without exercise, in adults with overweight or obesity
Authors: Collins Katherine A. , Ambrosio Fabrisia , Rogers Renee J. , Lang Wei , Schelbert Eric B. , Davis Kelliann K. , Jakicic John M. 
Published: June 2023

Introduction: Klotho is a protein associated with protection from aging-related diseases and health conditions. Obesity is associated with lower Klotho concentrations. Thus, this secondary analysis of adults with obesity examined 1) the change in serum Klotho concentration in response to a behavioral weight loss intervention by the magnitude of weight loss achieved; and 2) the association among serum Klotho concentration and weight, body composition, and cardiorespiratory fitness.Methods: Participants were randomized to either diet alone (DIET), diet plus 150 min of physical activity per week (DIET + PA150), or diet plus 250 min of physical activity per week (DIET + PA250). Participants [n = 152; age: 45.0 ± 7.9 years; body mass index (BMI): 32.4 ± 3.8 kg/m2] included in this secondary analysis provided blood samples at baseline, 6-, and 12 months, and were classified by weight loss response (Responder: achieved ≥10% weight loss at 6 or 12 months; Non-responder: achieved &lt;5% weight loss at both 6 and 12 months). Serum Klotho was measured using a solid-phase sandwich enzyme-linked immunosorbent assay (ELISA). Analyses of covariance (ANCOVA’s) were used to examine changes in weight, body composition, cardiorespiratory fitness, and Klotho concentration by weight loss response across the 12-month weight loss intervention.Results: Responders had a greater reduction in measures of weight and body composition, and a greater increase in cardiorespiratory fitness, compared to Non-Responders (p &lt; 0.05). Change in Klotho concentration differed between Responders and Non-Responders (p &lt; 0.05), with the increase in Klotho concentration from baseline to 6 months for Responders being statistically significant. The 6-month change in Klotho concentration was inversely associated with the 6-month change in weight (rs = −0.195), BMI (rs = −0.196), fat mass (rs = −0.184), and waist circumference (rs = −0.218) (p-values &lt;0.05).Discussion: Findings provide evidence within the context of a behavioral intervention, with and without exercise, that change in Klotho concentration is significantly different between adults with weight loss ≥10% compared to &lt;5% across 12 months. These findings suggest that weight loss and reduction in fat mass may be favorably associated with the change in Klotho concentration. This may reduce the risk of negative health consequences associated with accelerated aging in middle-aged adults.
Generalized permanent dentition fluorosis severity becomes less evident over time among a birth cohort
Authors: Levy Steven M. , Warren John J. , Kolker Justine L. , Weber-Gasparoni Karin 
Published: June 2023

ObjectivesThere are relatively few cohort studies which have examined changes in fluorosis appearance over time, and none of these have assessed changes in generalized fluorosis. In this analysis, we quantified and assessed changes in multiple measures of generalized fluorosis severity through childhood, adolescence, and young adulthood.MethodsParticipants were from the Iowa Fluoride Study, a birth cohort recruited from 1992 to 1995. Permanent dentition fluorosis exams were carried out at ages 9, 13, 17, and 23 years using the Fluorosis Risk Index (FRI). Generalized fluorosis was assessed using mean FRI scores at the tooth- and person-level as well as a five-category measure of generalized fluorosis. Generalized fluorosis prevalence and severity was summarized at each time point and differences in adjacent time points were assessed using gamma statistics, signed-rank tests, and plotting changes in generalized fluorosis between adjacent time points.ResultsWe observed a statistically significant decline in the percentage of non-zero mean FRI scores at later exam ages at both the person- and tooth-levels. Based on our five-category generalized fluorosis measure, there were 34.0%–54.1% of participants with generalized fluorosis at baseline for each tooth group, and these percentages declined to 8.9%–27.2% at the age 23-year exam.ConclusionsWe observed a statistically significant decline in generalized fluorosis severity scores and overall prevalence at later exam ages across all three measures of generalized fluorosis severity. This trend should be accounted for when estimating the prevalence of fluorosis in a population using fluorosis severity data collected in children and adolescents.
Determining the Provenance of Traded Wildlife in the Philippines
Authors: Brandis Kate J. , Meagher Phoebe , Schoppe Sabine , Zawada Kyle , Widmann Indira , Widmann Peter , Dolorosa Roger G. , Francis Roxane 
Published: June 2023

The illegal wildlife trade is a significant threat to global biodiversity, often targeting already threatened species. In combating the trade, it is critical to know the provenance of the traded animal or part to facilitate targeted conservation actions, such as education and enforcement. Here, we present and compare two methods, portable X-ray fluorescence (pXRF) and stable isotope analysis (SIA), to determine both the geographic and source provenance (captive or wild) of traded animals and their parts. Using three critically endangered, frequently illegally traded Philippine species, the Palawan forest turtle (Siebenrockiella leytensis), the Philippine cockatoo (Cacatua haematuropygia), and the Philippine pangolin (Manis culionensisis), we demonstrate that using these methods, we can more accurately assign provenance using pXRF data (x¯ = 83%) than SIA data (x¯ = 47%). Our results indicate that these methods provide a valuable forensic tool that can be used in combating the illegal wildlife trade.
Fluctuación poblacional de Chaetanaphothrips signipennis en Musa sp frente al depredador Amblyseius swirskii
Authors: Barrezueta-Unda Salomon Alejandro , Cabezas Zhumi Bryan Leonardo 
Published: June 2023

La principal plaga que afecta a los frutos del banano es Chaetanaphothrips signipennis (Thysanoptera: Thripidae), conocido como el trips de la mancha roja del banano. Una forma de control es mediante el control biológico con el ácaro depredador Amblyseius swirskii. En este contexto, el objetivo del trabajo fue comparar la fluctuación poblacional de C. signipennis, y después de introducir A. swirskii en el cultivo de banano. Para esto, en una bananera se aplicó en todo el área cultivada 250 ácaros por cada racimo recién embolsado, luego se delimitó tres parcelas donde se tomó planta al azar para contabilizar los adultos de C. Signipennis y A. swirskii durante 12 semanas. Las observaciones fueron entre los bordes de las hojas y los márgenes interiores del pseudotallo. La suma de las poblaciones por semana fueron muy heterogéneas. La suma total de C. signipennis fue de 1147 trips, inferior al registro de A. swirskii de 4860 ácaros. Las poblaciones de C. Signipennis se redujo desde la segunda semana, pero se volvió a incrementar en la semana 11, a diferencia de A. Swirskii que se incrementa cada dos semanas. La distribución poblacional de C. Signipennis en los tres tramos que se dividieron las parcelas fue agregada, concentrando la mayor población entre el centro y el final de las parcelas. Distribución diferente en A. Swirskii que mostró una distribución homogénea en las parcelas.
GAMBARAN PENGETAHUAN KESEHATAN GIGI DAN MULUT DAN PERILAKU MEROKOK SISWA KELAS XII TEKNIK MESIN SMKN 1 KATAPANG KABUPATEN BANDUNG TAHUN 2022
Authors: Nurunnisa Shabrina , Octaviana Devy , Widyastuti Tri , Praptiwi Yenni Hendriani 
Published: June 2023

Kebiasaan merokok merupakan salah satu pencetus timbulnya gangguan penyakit rongga mulut serta berpengaruhnya terhadap estetika, antara lain dapat mengakibatkan perubahan warna gigi, penebalan mukosa, gingivitis, bahkan penyakit kanker mulut. Kandungan rokok yang berupa tembakau, nikotin, karbon monoksida, ammonia, dan derivat-derivat lainnya dapat mengiritasi rongga mulut saat dikonsumsi karena adanya pembakaran. Data Riset Riskesdas 2010, persentase usia mulai merokok di Indonesia terbesar yaitu pada usia 15-19 tahun (43,4%). Data tersebut menunjukkan bahwa masyarakat Indonesia paling banyak mulai merokok pada usia remaja. Tujuan penelitian ini adalah untuk diketahuinya gambaran pengetahuan kesehatan gigi dan mulut dan perilaku merokok pada siswa kelas XII Teknik Mesin SMKN 1 Katapang. Jenis penelitian ini adalah penelitian deskriptif dengan pendekatan survey. Pengambilan sampel penelitian ini dilakukan dengan total sampling. Cara kerja penelitian ini dengan pemberian kuesioner kepada responden. Hasil penelitian ini menunjukkan subjek sebanyak 68 siswa dimana 47 siswa merokok dan 21 siswa tidak merokok. Dan pada pengetahuan kesehatan gigi dan mulut pengetahuan baik sebanyak 10 siswa (14,07%),subjek yang memiliki pengetahuan sedang sebanyak 25 siswa (38,8%), dan subjek yang memiliki pengetahuan kurang sebanyak 33 siswa (48,5%). Dan untuk pengetahuan kesehatan gigi dan mulut dan perilaku merokok sebanyak 26 siswa yang merokok dengan pengetahuan kurang. Disimpulkan bahwa perilaku yang merokokmemiliki pengetahuan dengan kategori kurang mengenai kesehatan gigi dan mulut.
Pengaruh Penyuluhan Modifikasi Video Terhadap Tingkat Pengetahuan Pentingnya Menjaga Kesehatan Gigi Dan Mulut Dalam Pencegahan Karies
Authors: Fitriani Sania , Restuning Sekar , Mulyanti Sri , Herijulianti Eliza 
Published: June 2023

ABSTRAK
Kesehatan gigi dan mulut merupakan bagian dari kesehatan tubuh dan mempengaruhi kesehatan tubuh secara keseluruhan dan tidak dapat dipisahkan. Sekitar 80% penduduk Indonesia menderita kerusakan gigi karena berbagai alasan. Siswa Sekolah Menengah Atas (SMA) umumnya pada rentan usia antara 15 hingga 19 tahun dan beberapa masih remaja. Masa remaja ialah masa transisi perkembangan antara anak ke dewasa, dengan perubahan keadaan fisik, kognitif, dan psikologis sosial. Siswa SMA berada pada tahap perkembangan kognitif operasional formal. Penelitian menggunakan media modifikasi video mengenai menjaga kesehatan gigi dan mulut. Tujuan mengetahui tingkat pengetahuan pentingnya menjaga kesehatan gigi dan mulut dalam pencegahan karies melalui modifikasi video tentang pentingnya menjaga kesehatan gigi dan mulut di MAN 4 Sukabumi. Penelitian ini mengunakan jenis penelitian analitik dengan desain penelitian quasi eksperimen (eksperimen semu). sampel diambil menggunakan total sampling dengan jumlah 151 orang. Analisa penelitian menggunakan uji Wilcoxon. Hasil penelitian didapatkan hasil nilai rata-rata pretest yaitu 8,38, hasil nilai rata-rata posttest yaitu 8,92 dan selisih yaitu sebesar 0,54, dengan nilai p value = 0.000 ≤ 0.05 yang berarti ada pengaruh media modifikasi video terhadap peningkatan pengetahuan. Disimpulkan bahwa adanya peningkatan pengetahuan siswa kelas X di MAN 4 Sukabumi dalam menjaga kesehatan gigi siswa MAN 4 Sukabumi. Media video juga dapat dijadikan sebagai promosi kesehatan yang dapat dijadikan meningkatkan kesadaran tentang menjaga kesehatan gigi dan mulut.
The Relationship Of Coffee Consumption Habits With The Occurence Of Stain In Community In Sirap Village
Authors: Aprilina Reza Asri , Nurjannah Neneng , Ningrum Nining , Widyastuti Tri 
Published: June 2023

Stain is a staining on the teeth caused by the attachment of food, drink, or other content, such as coffee. The habit of consuming coffee is one of the factors that cause stains due to caffeine contained in coffee. The purpose of this study was to determine the relationship between coffee consumption habits and the occurrence of stains on teeth.
This type of research is analytic with a cross sectional research design which was carried out in March 2022 on 50 respondents with a sampling technique using purposive sampling technique. The habit of consuming coffee was obtained through interviews using a questionnaire, while stains on teeth were obtained through direct examination results.
The results of univariate data showed that most of the respondents had stains with moderate criteria, namely 25 respondents (50%). The results of the Somers'd gamma test showed that there was a relationship between the length and amount of coffee consumed and the occurrence of stains, namely p < 0.05 and there was no relationship between the type of coffee consumed and the occurrence of stains, namely p > 0.05.
The Relationship Of Smokers’ Behavior With Dental And Mouth Cleaning At SMAN 1 Majalaya, Bandung Regency
Authors: Andriana Icha Khoerany , Sirait Tiurmina , Herijulianti Eliza , Insanuddin Isa 
Published: June 2023

Introduction: Smoking is a global health problem because it can cause various diseases and even death. The prevalence of smoking in Indonesia is 28.8%, and in West Java the prevalence of smoking is in the first rank of 34 provinces which is 32.0%, and the prevalence of smoking at the age of >15 years in 2018 is at a high rate (62.9 %). A number of studies show that smokers start smoking at the age of 11 and 13 years and 85-90% start smoking before the age of 18 years, and high school students with peers who smoke are 5 times more likely to smoke than non-smokers. have friends who smoke. In addition, there are several factors that cause students to smoke, including students having the motivation to smoke cigarettes because they want to try it after suggestions appear to try smoking from within themselves after seeing people around them smoking. Smoking not only has a systemic effect, but can also cause pathological conditions in the oral cavity. Teeth and soft tissues of the oral cavity are parts that can be damaged by smoking.
Methods: This research is a non-experimental quantitative research and uses the type of analytical research. Data were collected by distributing questionnaires containing questions about smoking behavior and followed by examination of the Hygiene Index on 40 student respondents of SMAN 1 Majalaya, Bandung Regency according to the criteria. The statistical test carried out is the Chi-Square test.
Results: The behavior of smokers and the dental and oral hygiene of the respondents were in the moderate category. And obtained the relationship between smoking behavior with dental and oral hygiene (p = 0.011 <0.05).
Conclusion: There is a significant relationship between smoking behavior and oral hygiene at SMAN 1 Majalaya, Bandung Regency.
Conjuntivite purulenta com isolamento bacteriano em uma Chinchilla lanigera
Authors: Gonçalves Daniele de Oliveira 
Published: June 2023

O presente trabalho tem o objetivo de descrever a ocorrência de conjuntivite purulenta em uma Chinchilla lanigera, heterobege, macho, não castrado e com 4 anos de idade. Ao realizar o exame clínico oftalmológico, constatou-se grande quantidade de exsudato ocular mucopurulento no olho esquerdo. Organismos bacterianos como Staphylococcus aureus e Streptococcus sp. foram identificados em amostras microbiológicas coletadas com swab nas regiões da córnea, pálpebra e do saco conjuntival. Infecções causadas por bactérias oportunistas são relatadas nesses animais e a anatomia ocular da espécie leva a predisposição de lesões. As chinchilas podem desenvolver conjuntivite secundária à má oclusão dentária, contudo, o paciente não apresentava histórico ou sinais dessa doença. Fatores como objetos pontiagudos no viveiro, o pó utilizado no banho da chinchila e produtos irritantes foram os principais suspeitos na causa da enfermidade. O tratamento para conjuntivite bacteriana é realizado com medicação tópica com ou sem terapia antimicrobiana oral. Foi estabelecido tratamento com colírio a base de cloridrato de Ciprofloxacino e dexametasona (Ciprixin Dexa®), obtendo-se pleno êxito com o procedimento. É esperado que os casos de doenças oftálmicas aumentem devido ao número crescente da criação das chinchilas. A compreensão da morfologia e parâmetros fisiológicos da espécie permite um melhor diagnóstico oftalmológico.
ANALISIS TINGKAT KECELAKAAN KERJA DI PABRIK KELAPA SAWIT PT. ABC MENGGUNAKAN JOB SAFETY ANALYSIS
Authors: Yardani Jesi , Akbar Jamaluddin , Ulimaz Almira 
Published: June 2023

ABSTRACT

This study aims to analyze the factors that influence the level of work accidents at the palm oil mill of PT. ABC and test the effectiveness of the Job Safety Analysis method in reducing the risk of work accidents in factories. Through observation, identification, risk analysis, as well as interviews and discussions, this study found that human factors, work environment factors, and tool and machine factors influence the rate of work accidents in factories. The results also show that the Job Safety Analysis method can be effective in reducing the risk of work accidents at the PT. ABC. These findings make an important contribution to companies and society in improving work safety in factories and show the importance of using the Job Safety Analysis method to reduce the risk of work accidents.

Keywords: Job Safety Analysis, Occupational Health and Safety, Palm oil mill

ABSTRAK

Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi tingkat kecelakaan kerja di pabrik minyak kelapa sawit PT. PQRS dan menguji efektivitas metode Job Safety Analysis dalam mengurangi risiko kecelakaan kerja di pabrik. Melalui observasi, identifikasi, analisis risiko, serta wawancara dan diskusi, penelitian ini menemukan bahwa faktor manusia, faktor lingkungan kerja, dan faktor alat dan mesin mempengaruhi tingkat kecelakaan kerja di pabrik. Hasil penelitian juga menunjukkan bahwa metode Job Safety Analysis dapat efektif dalam mengurangi risiko kecelakaan kerja di pabrik minyak kelapa sawit PT. ABC. Temuan ini memberikan kontribusi penting bagi perusahaan dan masyarakat dalam meningkatkan keselamatan kerja di pabrik dan menunjukkan pentingnya penggunaan metode Job Safety Analysis untuk mengurangi risiko kecelakaan kerja.

Kata kunci: Job Safety Analysis, Keselamatan dan Kesehatan Kerja, Pabrik kelapa sawit
Myocardial Infarction as Predictor of Cognitive Disorders in Cardiovascular Patients: A Literature Review
Authors: Гордеев И.А. , Куторова Е.Э. , Акимова Н.C. 
Published: June 2023

Выполнен анализ исследований, посвященных изучению проблемы связи состояния центральной нервной и сердечно-сосудистой систем у пациентов с инфарктом миокарда. Приводятся сведения о том, что несвоевременные диагностика и коррекция когнитивных расстройств могут ассоциироваться с их прогрессированием и развитием деменции, приводящей к инвалидизации пациента. Когнитивные расстройства имеют несомненное социально-экономическое значение как с точки зрения практического здравоохранения, так и в отношении каждого отдельного пациента. По данным литературы, когнитивные нарушения являются фактором, увеличивающим показатели общей смертности в популяции. Показано, что лица, перенесшие инфаркт миокарда, в 5 раз чаще страдают нарушениями когнитивного статуса по сравнению с общей популяцией.
The article presents a review of literature on a problem of the relationships between the central nervous system and the cardiovascular system in the patients with myocardial infarction. The contribution of comorbid conditions in mechanisms of cognitive disorders development caused by ischemic heart disease is of ongoing scientific and clinical interest. Data are presented indicating that untimely diagnosis and correction of cognitive disorders may be associated with their progression, so the cognitive disorders have an important socio-economic significance. The growing number of evidence suggests that excessive decrease in cognitive functions affects the survival of patients with cardiovascular diseases. According to clinical trials review, cognitive impairments increase overall mortality rates in the population. Myocardial infarction is one of the important factors of cognitive disorders development.