bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term cardiometabolic health in people born after assisted reproductive technology: a multi-cohort analysis
Authors: Elhakeem Ahmed , Taylor Amy E , Inskip Hazel M , Huang Jonathan Y , Mansell Toby , Rodrigues Carina , Asta Federica , Blaauwendraad Sophia M , Håberg Siri E , Halliday Jane , Harskamp-van Ginkel Margreet W , He Jian-Rong , Jaddoe Vincent W V , Lewis Sharon , Maher Gillian M , Manios Yannis , McCarthy Fergus P , Reiss Irwin K M , Rusconi Franca , Salika Theodosia , Tafflet Muriel , Qiu Xiu , Åsvold Bjørn O , Burgner David , Chan Jerry K Y , Gagliardi Luigi , Gaillard Romy , Heude Barbara , Magnus Maria C , Moschonis George , Murray Deirdre , Nelson Scott M , Porta Daniela , Saffery Richard , Barros Henrique , Eriksson Johan G , Vrijkotte Tanja G M , Lawlor Deborah A 
Published: February 2023

Abstract

Aims
To examine associations of assisted reproductive technology (ART) conception (vs. natural conception: NC) with offspring cardiometabolic health outcomes and whether these differ with age.

Methods and results
Differences in systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), lipids, and hyperglycaemic/insulin resistance markers were examined using multiple linear regression models in 14 population-based birth cohorts in Europe, Australia, and Singapore, and results were combined using meta-analysis. Change in cardiometabolic outcomes from 2 to 26 years was examined using trajectory modelling of four cohorts with repeated measures. 35 938 (654 ART) offspring were included in the meta-analysis. Mean age ranged from 13 months to 27.4 years but was &lt;10 years in 11/14 cohorts. Meta-analysis found no statistical difference (ART minus NC) in SBP (−0.53 mmHg; 95% CI:−1.59 to 0.53), DBP (−0.24 mmHg; −0.83 to 0.35), or HR (0.02 beat/min; −0.91 to 0.94). Total cholesterol (2.59%; 0.10–5.07), HDL cholesterol (4.16%; 2.52–5.81), LDL cholesterol (4.95%; 0.47–9.43) were statistically significantly higher in ART-conceived vs. NC offspring. No statistical difference was seen for triglycerides (TG), glucose, insulin, and glycated haemoglobin. Long-term follow-up of 17 244 (244 ART) births identified statistically significant associations between ART and lower predicted SBP/DBP in childhood, and subtle trajectories to higher SBP and TG in young adulthood; however, most differences were not statistically significant.

Conclusion
These findings of small and statistically non-significant differences in offspring cardiometabolic outcomes should reassure people receiving ART. Longer-term follow-up is warranted to investigate changes over adulthood in the risks of hypertension, dyslipidaemia, and preclinical and clinical cardiovascular disease.
3-D Simulations of earthquakes rupture jumps: 1. Homogeneous pre-stress conditions
Authors: Kroll Kayla A , Dieterich James H , Richards-Dinger Keith B , Oglesby David D 
Published: February 2023

SUMMARYObservational and modelling studies indicate that earthquake ruptures can jump between fault sections as large as ∼3 and ∼5 km for compressional and extensional offsets, respectively. Here, we compare characteristics of the rupture jump process on parallel but offset fault sections from traditional 3-D dynamic rupture simulations governed by slip weakening friction using the finite element code, FaultMod, to those from quasi-dynamic simulations governed by rate- and state-dependent friction (rate-state friction) using the code RSQSim. These simulations use spatially uniform initial stresses. For a variety of measures the rupture renucleation position on the offset fault, the rate-state friction and slip weakening friction models produce very similar results. The principal difference is the additional occurrence of delayed rupture jumps that arise from the time- and stress-dependent nucleation that is characteristic of rate-state friction. For immediate rupture jumps, models with slip weakening friction span greater offsets than those with rate-state friction. However the jump distances are nearly identical when delayed rupture jumps are included in the comparisons. We propose that delayed rupture jumps are the likely mechanism for adjacent large-earthquake pairs and clusters. Based on the similarity of renucleation positions with both dynamic and quasi-dynamic models, we conclude that the renucleation positions for rupture initiation on the receiver fault (separated by less than ∼3 km from the source fault) are primarily controlled by static stress changes induced by slip on the initiating fault. However, in light of the slightly greater maximum jump distances (&gt;3 km) seen with the dynamic slip weakening friction model, dynamic stress changes from seismic waves play an increasingly important role as offset distances increase.
Dynamics of Anti-influenza Mucosal IgA Over a Season in a Cohort of Individuals Living or Working in a Long-term Care Facility
Authors: Hitchings Matt D T , Borgert Brooke A , Shir Adam , Yang Bingyi , Grantz Kyra H , Ball Jacob , Moreno Carlos A , Rand Kenneth , Small Parker A , Fowke Keith R , Cummings Derek A T 
Published: February 2023

Abstract

Background
Serological surveys are used to ascertain influenza infection and immunity, but evidence for the utility of mucosal immunoglobulin A (IgA) as a correlate of infection or protection is limited.

Methods
We performed influenza-like illness (ILI) surveillance on 220 individuals living or working in a retirement community in Gainesville, Florida from January to May 2018, and took pre- and postseason nasal samples of 11 individuals with polymerase chain reaction (PCR)-confirmed influenza infection and 60 randomly selected controls. Mucosal IgA against 10 strains of influenza was measured from nasal samples.

Results
Overall, 28.2% and 11.3% of individuals experienced a 2-fold and 4-fold rise, respectively, in mucosal IgA to at least 1 influenza strain. Individuals with PCR-confirmed influenza A had significantly lower levels of preseason IgA to influenza A. Influenza-associated respiratory illness was associated with a higher rise in mucosal IgA to influenza strains of the same subtype, and H3N2-associated respiratory illness was associated with a higher rise in mucosal IgA to other influenza A strains.

Conclusions
By comparing individuals with and without influenza illness, we demonstrated that mucosal IgA is a correlate of influenza infection. There was evidence for cross-reactivity in mucosal IgA across influenza A subtypes.
Edge effect of wide spectrum denoising in super-resolution microscopy
Authors: Cheng Tao , Wang Yingshan 
Published: February 2023

Abstract
During the stochastic optical reconstruction microscope (STORM) raw image acquisition in super-resolution microscopy, noise is inevitable. Noise not only reduces the temporal and spatial resolution of the super-resolution image but also leads to the failure of super-resolution image reconstruction. Wide spectrum denoising (WSD) can effectively remove various random noises (such as Poisson noise and Gaussian noise) from the STORM raw image to improve the super-resolution image reconstruction. We found that there is an obvious edge effect in WSD, and its influence on STORM raw image denoising and super-resolution image reconstruction is studied. We then proposed the method of restraining edge effect. The simulation and real experiment results show that edge trimming can effectively suppress the edge effect, thus leading to better super-resolution image reconstruction.
Increased RSV-A Bronchiolitis Severity in RSV-Infected Children Admitted to a Reference Center in Catalonia (Spain) Between 2014 and 2018
Authors: Vila Jorgina , Lera Esther , Peremiquel-Trillas Paula , Andrés Cristina , Martínez Laia , Barceló Irene , Carsi Ariadna , Balcells Joan , Ángel Rodrigo-Pendás José , Soler-Palacín Pere , Rodrigo Carlos , Antón Andrés 
Published: February 2023

Abstract
Between 2014 and 2018, we evaluated the severity of 687 cases of bronchiolitis caused by respiratory syncytial virus (RSV) in Catalonia, Spain. Compared to RSV-B, RSV-A cases required intensive care (adjusted relative risk (aRR) = 1.44, p &lt; 0.01) and respiratory support (aRR = 1.07, p &lt; 0.01) more often; hospital stay was one day longer (p &lt; 0.01). Subgroup identification may aid clinical evaluation and seasonal healthcare planning.
Millimeter-wave spectrum of 2-propanimine
Authors: Zou Luyao , Guillemin Jean-Claude , Belloche Arnaud , Jørgensen Jes K , Margulès Laurent , Motiyenko Roman A , Groner Peter 
Published: February 2023

ABSTRACT
Up to date, only six imines have been detected in the interstellar medium. The 3-carbon imine, 2-propanimine ((CH3)2C = NH), is predicted to be the structural isomer with the lowest energy in the C3H7N group, and appears to be a good candidate for astronomical searches. Unexpectedly, no microwave or millimeter wave spectrum is available for 2-propanimine. In this work, we provide the first high-resolution millimeter wave spectrum of 2-propanimine and its analysis. With the guide of this laboratory measurement, we aim to search for 2-propanimine in two molecule-rich sources Sgr B2(N) and IRAS 16293–2422 using observations from the Atacama Large Millimeter/submillimeter Array (ALMA). Starting from a synthesized sample, we measured the spectrum of 2-propanimine from 50 to 500 GHz, and the ground state lines are successfully assigned and fitted using XIAM and ERHAM programs with the aid of theoretical calculations. The barriers to internal rotation of the two CH3 tops are determined to be 531.956(64) cm−1 and 465.013(26) cm−1 by XIAM. These data are able to provide reliable prediction of transition frequencies for astronomical search. Although a few line matches exist, no confirmed detection of 2-propanimine has been found in the hot molecular core Sgr B2(N1S) and the Class 0 protostar IRAS 16293B. Upper-limits of its column density have been derived, and indicate that 2-propanimine is at least 18 times less abundant than methanimine in Sgr B2(N1S), and is at most 50 – 83 per cent of methanimine in IRAS 16293B.
Hickson-like compact groups inhabiting different environments
Authors: Taverna A , Salerno J M , Daza-Perilla I V , Díaz-Giménez E , Zandivarez A , Martínez H J , Ruiz A N 
Published: February 2023

ABSTRACT
Although compact groups (CGs) of galaxies have been envisioned as isolated extremely dense structures in the Universe, it is accepted today that many of them could be not as isolated as thought. In this work, we study Hickson-like CGs identified in the Sloan Digital Sky Survey Data Release 16 to analyse these systems and their galaxies when embedded in different cosmological structures. To achieve this goal, we identify several cosmological structures where CGs can reside: nodes of filaments, loose groups, filaments, and cosmic voids. Our results indicate that 45 per cent of CGs do not reside in any of these structures, i.e. they can be considered non-embedded or isolated systems. Most of the embedded CGs are found inhabiting loose groups and nodes, while there are almost no CGs residing well inside cosmic voids. Some physical properties of CGs vary depending on the environment they inhabit. CGs in nodes show the largest velocity dispersions, the brightest absolute magnitude of the first-ranked galaxy, and the smallest crossing times, while the opposite occurs in non-embedded CGs. When comparing galaxies in all the environments and galaxies in CGs, CGs show the highest fractions of red/early-type galaxy members in most of the absolute magnitudes ranges. The variation between galaxies in CGs inhabiting one or another environment is not as significant as the differences caused by belonging or not to a CG. Our results suggest a plausible scenario for galaxy evolution in CGs in which both large-scale and local environments play essential roles.
Accretion-modified stellar-mass black hole distribution and milli-Hz gravitational wave backgrounds from galaxy centre
Authors: Wang Mengye , Ma Yiqiu , Wu Qingwen 
Published: February 2023

ABSTRACTGas accretion of embedded stellar-mass black holes (sBHs) or stars in the accretion disc of active galactic nuclei  (AGNs) will modify the mass distribution of these sBHs and stars, which will also affect the migration of the sBHs/stars. With the introduction of the mass accretion effect, we simulate the evolution of the sBH/star distribution function in a consistent way by extending the Fokker–Planck equation of sBH/star distributions to the mass-varying scenario, and explore the mass distribution of sBHs in the nuclear region of the galaxy centre. We find that the sBHs can grow up to several tens solar mass and form heavier sBH binaries, which will be helpful for us to understand the black-hole mass distribution as observed by the current and future ground-based gravitational wave detectors (e.g. LIGO/Virgo, ET and Cosmic Explorer). We further estimate the event rate of extreme mass-ratio inspirals (EMRI) for sBH surrounding the massive black hole and calculate the stochastic gravitational wave (GW) background of the EMRIs. We find that the background can be detected in future space-borne GW detectors after considering the sBHs embedded in the AGN disc, while the mass accretion has a slight effect on the GW background.
The Double Dividend of a Joint Tariff and VAT Reform: Evidence from Iran
Authors: Yousefi Kowsar , Vesal Mohammad 
Published: February 2023

AbstractThis paper provides empirical evidence on a novel complementarity between VAT and trade taxes. Downstream domestic firms require VAT receipts from importers to claim VAT on purchases, increasing incentives for honest reporting of imports. Trade gap, the difference between mirror and domestic trade reports in Iran at 6-digit HS disaggregation, is used to measure this complementarity. Iran introduced VAT in 2008 and, since then, has increased its rate from 3 to 9 percent. Difference-in-differences estimates show that a 1 percentage point increase in the VAT rate reduces the trade gap by about 2 percent. Consistent with the compliance mechanisms for VAT, a smaller effect for consumer products that have a shorter value chain is observed. Findings suggest that replacing tariffs with VAT results in a double dividend. Tax revenue might increase due to better tariff compliance and a broader VAT base.
Genome Sequence Resource of Fusarium oxysporum Strain PkF01: The Causative Agent of Rhizome Rot of Polygonatum kingianum
Authors: Su Jianyun , Dong Xian , Dong Jiahong , Ji Pengzhang , Zhang Lei 
Published: February 2023

Fusarium oxysporum strain PkF01 is the causal agent of Polygonatum kingianum rhizome rot. Here, we report, for the first time, the genome assemblies of the F. oxysporum strain PkF01 using the PacBio Sequel system. We obtained a total base number of 51.27 Mb in 87 contigs. The number of scaffolds and scaffold N50 were 86 and 2.46 Mb, with a 47.55% GC content. The number of coding sequences was 17,265, with total length of 36.61 Mb, average length of 1.77 kb, and a gene density of 0.34 kb. A total of 11,447, 14,734, 10,759, and 4,434 genes were annotated using the Pfam, COG, GO, and KEGG databases, respectively. A total of 764, 335, 1,572, 216, 4,245, 1,591, 2,242, and 1,926 genes were annotated using the CAZy, CYP450, DFVF, CARD, PHI, SignalP, TCDB, and TMHMM databases, respectively. Collinearity analysis showed that the PkF01 genome shared more homologous genomic regions with F. oxysporum f. sp. lilii strain Fol39 than with F. oxysporum f. sp. lycopersici strain Fol4287, indicating that the PkF01 genome is more closely related to the Fol39 rather than the Fol4287 genome. The high-quality genome sequences of PkF01 will provide a valuable resource for not only investigating both the pathogenicity mechanism and host specificity in F. oxysporum but also exploring disease control measures. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
Psychiatric sequelae and interventions in critically ill trauma survivors
Authors: Chow Jarva , Lancman Benn 
Published: February 2023

Purpose of review
Psychiatric disorders following trauma impact functional recovery in trauma survivors and are a significant source of disability. Although research has traditionally focused on the physical sequelae of trauma, more attention is being directed towards the significant morbidity and mortality associated with the psychologic sequelae of trauma. This review evaluates the existing literature.

Recent findings
Use of multidisciplinary collaborative programmes in combination with psychiatric treatment and pharmacotherapy may be necessary to improve the care of trauma patients with psychiatric sequelae. Improving identification of vulnerable patients may help in the prevention and treatment of psychiatric disorders and is an area of current research initiatives.

Summary
There are few interventions that have demonstrated efficacy in managing the psychiatric sequelae of trauma. The development of strategies to guide early identification of at-risk patients and recommend prevention and treatment may improve the care of trauma survivors.
Acute pain management and long term outcomes
Authors: Delande Simon , Lavand’homme Patricia 
Published: February 2023

Purpose of review
The acute inflammatory reaction induced by tissue trauma causes pain but also promotes recovery. Recovery is highly variable among peoples. Effective acute pain (AP) management is very important but remains suboptimal what could affect long term outcomes. The review questions the impact of either failure or effectiveness of AP treatments and the choice of analgesic drugs on different long-term outcomes after tissue trauma.

Recent findings
Pain control during mobilization is mandatory to reduce the risk of complications which exacerbate and prolong the inflammatory response to trauma, impairing physical recovery. Common analgesic treatments show considerable variability in effectiveness among peoples what argues for an urgent need to develop personalized AP management, that is, finding better responders to common analgesics and targeting challenging patients for more invasive procedures. Optimal multimodal analgesia to spare opioids administration remains a priority as opioids may enhance neuroinflammation, which underlies pain persistence and precipitates neurocognitive decline in frail patients. Finally, recent findings demonstrate that AP treatments which modulate nociceptive and inflammatory pain should be used with caution as drugs which inhibit inflammation like nonsteroidal antiinflammatory drugs and corticoids might interfere with natural recovery processes.

Summary
Effective and safe AP management is of far greater importance than previously realized. Evidence of suboptimal AP management in many patients and recent reports pointing out the impact of current treatments on long term outcomes argue for further research in the field.
The anesthetic approach to a patient with placenta accreta spectrum
Authors: Ioscovich Alexander , Weiss Adina , Shatalin Daniel 
Published: February 2023

The Purpose of This Review
Placenta accreta poses significant risk of morbidity and mortality to a laboring patient. Here we review available treatment options, highlight in bleeding prevention and diagnosis that have been shown to improve patient outcome, and provide best practice suggestions. We also discuss the decision-making process for choice of anesthesia, as it is not based on a gold-standard paradigm.

Recent findings
The use of resuscitative endovascular balloon occlusion of the aorta has been gaining popularity around the world. It has been shown to cause an equivocal reduction in perioperative bleeding in placenta accreta spectrum (PAS), reduce the rate of hysterectomies, and is a safe and relatively easy technique. There are other invasive radiology techniques that have also proven to be beneficial in bleeding prevention: balloon occlusion of hypogastric arteries intraoperatively, internal iliac artery embolization, and intraoperative ligation of the hypogastric or uterine arteries.

Summary
Optimal management of PAS begins with early and definitive diagnosis. A multidisciplinary approach along with preparation of special equipment and the use of a check-list maximize the chance for success. Anesthesia could be done with all types of regional or under general, considering case-by-case factors but most importantly choosing according to the institutions best facility and skill.
Paediatric pain management: from regional to virtual
Authors: Heydinger Grant , Karthic Anitra , Olbrecht Vanessa A. 
Published: February 2023

Purpose of review
Due to increased interest in opioid-sparing multimodal analgesic strategies both inside and outside of the operating room, anaesthesiologists have started to look towards regional anaesthesia as well as nonpharmacological pain-reducing techniques. The purpose of this article is to discuss current trends and recent developments in regional anaesthesia and virtual reality for paediatric pain management.

Recent findings
The development of novel fascial plane blocks has expanded regional options for anaesthesiologists, especially when neuraxial anaesthesia is not a viable or straightforward option. Other regional techniques, such as spinal anaesthesia and continuous epidural analgesia for infants and neonates, are becoming more popular, as more paediatric anaesthesiologists become familiar with these techniques. Virtual reality for paediatric pain management is a relatively new area of study that has shown promise, but more research needs to be done before widespread adoption of this practice becomes a reality. Various preexisting pain-reducing strategies such as distraction and biofeedback are being integrated with virtual reality to help optimize its effect on pain and anxiety for paediatric patients.

Summary
Regional anaesthesia and virtual reality are valuable tools that serve to alleviate pain in paediatric patients. Advances are being made within both fields in various healthcare settings for different types of pain. Over the next few years, they will likely both play an increasing role in paediatric pain management.
Anaesthesia role in enhanced recovery after surgery: a revolution in care outcomes
Authors: de Boer Hans D. , Scott Michael J. , Fawcett William J. 
Published: February 2023

Purpose of review
Enhanced recovery after surgery (ERAS) has revolutionized care outcomes. The purpose of this review is to provide an overview of how ERAS changed healthcare outcomes.

Recent findings
Development of multidisciplinary evidence-based ERAS guidelines for specific surgical specialties and systematic implementation of these guidelines resulted in improved healthcare outcomes, reduction in length of stay, reduction in complications and improved survival. The value of audit of the outcomes is essential for implementation and to improve healthcare. Healthcare economics analysis related to the implementation of ERAS showed significant cost savings up to a return to investment ratio of more than seven.

Summary
ERAS has revolutionized healthcare by developing evidence-based ERAS guidelines and systematic implementation of these guidelines. Audit of outcomes is essential, not only to improve healthcare but also to significantly save healthcare expenditures.