bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of different herbal teas on the color stability of nanohybrid and bulk-fill composites
Authors: Tunçdemir Makbule Tuğba , Dereli Zeynep , Bahar Ayşe 
Published: March 2023

Aim: The aim of this study is to investigate the effects of green tea and rosehip tea, on the color stability of nanohybrid and bulk-fill composite resins.
Methodology: A total of 60 disc-shaped samples were made from two types of A2 resin with nanohybrid (Tetric N Ceram, Ivoclar Vivadent, Schaan, Liechtenstein) and bulk-fill (Filtek Bulk-Fill, 3M ESPE, MN, USA) structure with the help of 10 mm diameter and 2 mm thick Teflon molds in this study. All samples were finished and polished with 4-stage (thick, medium, fine, superfine) polishing discs (Sof-lex, 3M ESPE, MN, USA) and kept in an oven at 37 °C for 24 hours. The samples, whose initial color measurements were made by spectrophotometer, were divided into subgroups for the control group and two different herbal teas (Green tea, Rosehip) (n=10). Color measurements were repeated, and ΔE values were calculated. Wilcoxon, Kruskal-Wallis, and Bonferroni tests were used to analyze the data (p < 0.05).
Results: There was no statistically significant difference in color change between the composite resins (p > 0.05). No significant color change was found for either the Tetric N-Ceram or Filtek Bulk-Fill composite resin samples immersed in distilled water (p > 0.05, ΔE<3.3).
Conclusion: Rosehip and green tea affect the color stability of composite resin restorations. Whereas the color change caused by green tea is at a clinically acceptable level, that stemming from rosehip tea falls within clinically unacceptable levels.

How to cite this article:
Tunçdemir MT, Dereli Z, Bahar A. The effect of different herbal teas on the color stability of nanohybrid and bulk-fill composites. Int Dent Res 2022;12(Suppl.1):103-7. https://doi.org/10.5577/intdentres.445

Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.
Awareness of Physiotherapy among Medical Professionals: A Cross Sectional Survey
Authors: Shah Rizwan , Ijaz Shazia , Ali Mehak , Saeed Sameena , Sultan Salma 
Published: March 2023

Objectives:
The study aim to determine the knowledge and awareness of physical therapy in medical professionals.
Methodology:
A descriptive, cross sectional study was used to examine 105 medical practitioners in Haripur. A standardized questionnaire was used in collecting data for 3 months, starting from June, 2018. Those participants (Medical practitioners) that were registered in different Haripur hospitals were included in sampling, whereas those hospitals/clinics participant that were not registered with PMDC (Pakistan Medical and Dental Council) and were not able to complete the questionnaire were excluded from the study. Prior to collecting the data, the individuals provided their written informed consent. According to the type of variable being studied, descriptive statistics were extracted from the response after it had been processed using SPSS-20.
Results:
The majority of medical professionals—94.3%—had shown to have good knowledge about physiotherapy. The findings indicated that 21% of medical practitioners receive physiotherapy care. According to the results, 84.76% of practitioners referred patients for physiotherapy care. Orthopedic cases were most frequently referred by doctors (554.28%), followed by sports injuries cases (10.47%), fitness cases (10.47%), cardiopulmonary cases (5.71%), women's health cases (5.71%), geriatric cases (3.83%), and the least in neurological cases (1.90%) and paediatric cases (1.90%). Physiotherapy was regarded as significant and very important in the health industry by about 40% and 47% of professionals, respectively. More, the majority of professionals, 87%, suggested that every hospital should have a physiotherapy department.
Conclusions:
Senior medical professionals have extremely positive perceptions of the responsibilities that physical therapists play in patient care and health promotion. Leading medical professionals understood physiotherapy well. Yet, doctors think that the major therapy strategy utilised by therapists is prescription exercises, and there is little knowledge of the most recent developments and inventions in the field of rehabilitation. The most successful physiotherapy treatments, according to practitioners, are orthopaedic treatment and treatment for sports injuries. Despite the fact that medical practitioners are generally aware of physiotherapy and its benefits, there is still need for progress in this area in order to get better functional results. Hence, proper steps must be done to raise awareness of and foster a positive attitude towards the profession of physiotherapy.
Performance of carbon nanotubes as supports of nickel-iron catalysts for carbon dioxide methanation
Authors:   , Mala Phanatchakorn 
Published: March 2023

Nowadays, an increase in CO2 emission is one of the main reasons of global warming. Many studies have tried to solve the problem by developing catalysts to efficiently convert CO2 into CH4. Herein, bimetallic Ni-Fe catalyst was studied to improve the catalyst activity of Ni-based catalyst which has low activity and is easily deactivated. Carbon nanotubes (CNTs) have been identified as one of the most promising nanomaterials with unique electrical, thermal, and mechanical properties. In this thesis, CNTs was synthesized from eucalyptus oil as a renewable carbon source and then employed as catalyst support material in methanation. Variations of synthesis conditions indicated the optimal pyrolysis temperature (Tpyro) of 900 °C and molar ratio of eucalyptus oil and ferrocene (moil/fer) of 3:1 to obtain highest content of CNTs and highest thermal stability. The synthesized CNTs were impregnated with nickel and iron with different weight ratios to be catalyst for CO2 methanation. The 30wt% Ni-Fe/CNT with weight ratio Ni:Fe of 70:30 could provide the highest CO2 conversion and methane yield at reaction temperature of 325 °C and molar ratio CO2:H2:He of 1:4:5 due to its highest reducibility and synergistic effect of Ni and inherited Fe presence in synthesized CNTs.
Influence of Aeroponic System on Growth and Yield Parameters of V-1 Mulberry
Authors: Nishchitha G. A. , Chandrashekhar S. , Bhaskar R. N. , Chikkalingaiah  
Published: March 2023

In an aeroponic system, nutrients are directly delivered to the plant roots, which results in the faster growth of crops. Furthermore, aeroponics has been extensively used as a research tool for many difficult-to-propagate plant species. The present investigation shows that the plants grown under the aeroponic system were recorded maximum for all the growth parameters except leaf area which was found maximum under nursery conditions. Among treatments, T3 (three buds per cutting) recorded the maximum for all growth parameters followed by T2 (two buds per cutting) and T1 (one bud per cutting). The interaction effect between propagation systems and the number of buds per cutting showed significant results. S1T3 (three budded cuttings under aeroponic system) recorded maximum for growth parameters viz., intermodal length (4.27 cm), plant height (44.39 cm), number of leaves (16.91), leaf yield (10.79 g/plant), whereas least was recorded by S2T1 i.e., one budded cuttings under nursery (2.39 cm, 35.47 cm, 5.88, 4.84g /plant respectively) at 60 DAT. However, S2T3 recorded a maximum leaf area of 95.96 cm2. From these results, it can be concluded that the aeroponic system could be effectively used for the production of V-1 mulberry saplings.
Computational modeling and in vitro evaluation identified natural product—Z218 as a novel Janus kinase 2 (JAK2) inhibitor to combat β‐thalassemia
Authors: Shaikh Ahmad 
Published: March 2023

AbstractAberrant activity of Janus kinase 2 (JAK2) is a known driver of several myeloproliferative disorders, including polycythemia vera, and thalassemia. Several inhibitors have been proposed to inhibit JAK2 activity in order to control the disease progression. Ruxolitinib and fedratinib that targets JAK2 kinase have been approved for use in myeloproliferative neoplasms patients. Experimental structures of JAK2 complexed with ruxolitinib provide insights into critical interactions of ruxolitinib. In this work, using a high‐throughput virtual screening followed by experimental validations, we have identified a novel natural product from ZINC database that interacts with JAK2 in a manner similar to ruxolitinib and inhibits the activity of JAK2 kinase. Molecular dynamics simulations and MMPBSA method show binding dynamics and stability of our identified lead compound. Kinase inhibition assays show that our identified lead molecule inhibits JAK2 kinase at a nanomolar range, indicating a plausibility that the identified lead molecule can be further studied as natural product inhibitor of JAK2 kinase.
Antimicrobial effect of pimozide by targeting ROS‐mediated killing in Staphylococcus aureus
Authors: Kumar Siddhartha , Sandeep Kumar , Kumar Rakesh , Kumar Antresh 
Published: March 2023

AbstractIn spite of the higher nosocomial and community‐acquired infections caused by Staphylococcus aureus, emerging drug resistance is a leading cause of increased mortality and morbidity associated with the overuse of antimicrobials. It is an emergent need to find out new molecules to combat such infections. In the present study, we analyzed the antibacterial effect of pimozide (PMZ) against gram‐positive and gram‐negative bacterial strains, including methicillin‐sensitive (MSSA) and methicillin‐resistant (MRSA) S. aureus. The growth of MSSA and MRSA was completely inhibited at concentrations of 12.5 and 100 μg/mL, respectively, which is referred to as 1× minimum inhibitory concentration (MIC). The cell viability was completely eliminated within 90 min of PMZ treatment (2× MIC) through reactive oxygen species (ROS)‐mediated killing without affecting cell membrane permeability. It suppressed α‐hemolysin production and biofilm formation of different S. aureus strains by almost 50% at 1× MIC concentration, and was found to detach matured biofilm. PMZ treatment effectively eliminates S. aureus infection in Caenorhabditis elegans and improves its survival by 90% and is found safe to use with no hemolytic effect on human and chicken blood tissues. Taken together, it is concluded that PMZ may turn out to be an effective antibacterial for treating bacterial infections including MSSA and MRSA.
Advances in Regioselective Functionalization of Endohedral Metallofullerenes†
Authors: Li Yanbang , Sun Yue , Kopcha William P. , Zhang Jianyuan 
Published: March 2023

Comprehensive SummaryEndohedral metallofullerenes (EMFs) are a family of molecules with metal clusters or ions encapsulated inside a fullerene cage. Their unique structures provide a powerful interface for organic chemists to manipulate metal elements. Over a decade ago, many reactions on empty fullerenes were adopted for EMFs, resulting in a series of reactions that are well‐established and reviewed in the literature. In recent years, new topics have emerged in EMF chemistry. First, new addition reactions were developed, notably some that are not based on known empty‐fullerene reactions. Second, considerable progress has been made on regioselective multi‐additions on EMFs. Finally, EMFs have been covalently conjugated with fullerene C60 to form functional materials. This Recent Advances article will focus on these new developments and discuss their implication for future directions of EMFs.
Optimal multiwave validation of secondary use data with outcome and exposure misclassification
Authors: Lotspeich Sarah C. , Amorim Gustavo G. C. , Shaw Pamela A. , Tao Ran , Shepherd Bryan E. 
Published: March 2023

AbstractObservational databases provide unprecedented opportunities for secondary use in biomedical research. However, these data can be error‐prone and must be validated before use. It is usually unrealistic to validate the whole database because of resource constraints. A cost‐effective alternative is a two‐phase design that validates a subset of records enriched for information about a particular research question. We consider odds ratio estimation under differential outcome and exposure misclassification and propose optimal designs that minimize the variance of the maximum likelihood estimator. Our adaptive grid search algorithm can locate the optimal design in a computationally feasible manner. Because the optimal design relies on unknown parameters, we introduce a multiwave strategy to approximate the optimal design. We demonstrate the proposed design's efficiency gains through simulations and two large observational studies.
Effects of sulforaphane on breast cancer based on metabolome and microbiome
Authors: Cao Shuyuan , Hu Shengjie , Jiang Ping , Zhang Zhan , Li Lei , Wu Qian 
Published: March 2023

AbstractSulforaphane (SFN) is a promising phytochemical with a wide range of antitumor activities. A comprehensive understanding of the effects of SFN on breast cancer based on the metabolome and microbiome is limited. Thus, we treated MCF‐7 cell‐transplanted nude mice with 50 mg/kg SFN. SFN inhibits breast cancer cell proliferation. SFN increased the levels of sulfate‐related metabolites and glutathione‐related metabolites and decreased tryptophan metabolites and methyl‐purine metabolites in urinary metabolic profile. SFN indirectly affected the activation of aryl hydrocarbon receptor by tryptophan metabolism. The ratio of SAM to methionine was decreased by SFN while the global DNA methylation was downregulated in tumor tissue. SFN decreased the sulfate‐reducing bacterium Desulfovibrio, which is related to reduced methylation capacity, and increased the genus Lactobacillus related to tryptophan metabolites with antitumor activities. In conclusion, we provide a perspective on the metabolome and microbiome to elucidate the antitumor activities of SFN.
Local‐level exposure to conflicts and child health: Evidence from Côte d'Ivoire
Authors: Wayoro Didier 
Published: March 2023

AbstractThis paper analyses the impact of the 2002–2011 period of instability in Côte d'Ivoire on child health. It uses two rounds of DHS surveys (1998–1999 and 2011–2012) and geo‐referenced data on conflict event locations, which gives more precise estimates of the effects of conflict on child welfare. Regressions using both spatial and temporal variations of conflict events across birth cohorts show a negative association between proximity to conflict events and child height‐for‐age z‐score. The study also suggests that maternal stress and disruptions of healthcare services are possible channels through which conflict affects child wellbeing.
Optimizing microdisplay requirements for pancake VR applications
Authors: Hsiang En‐Lin , Yang Zhiyong , Wu Shin‐Tson 
Published: March 2023

AbstractVirtual reality (VR) devices use imaging optics to magnify the microdisplay images for providing an immersive viewing experience. A microdisplay is preferred to have high‐resolution density and high dynamic range to meet the demanding requirements of human vision system (HVS), for example, visual acuity >60 pixels per degree and grayscale depth >10 bits. However, increasing resolution density and dynamic range often lead to a reduced optical efficiency and sophisticated fabrication process of the microdisplay panels. In this paper, we systematically analyze the image degradation mechanisms of VR devices caused by both imaging optics and microdisplay and find that the image degradation caused by imaging optics significantly unleash the requirements of microdisplay, such as contrast ratio, number of local dimming zones, and resolution density. For example, aberrations of the imaging optics reduce the resolution density requirement of the microdisplay, and stray light of the imaging optics relieves the contrast ratio requirement of the microdisplay. These results help prevent excessive design of microdisplay, for example, mini‐light‐emitting diode (LED) backlit liquid‐crystal displays (LCDs), organic LEDs, or micro‐LEDs, in a pancake lens‐based VR headset.
Einführung: Eltern im Stress?
Authors: Maly-Motta Hanna 
Published: March 2023

Zusammenfassung„Eltern, was habt ihr euch erwartet?“ – titelt die Süddeutsche Zeitung unter der Rubrik Stress. Stress im Rahmen von Elternschaft bzw. das Wohlbefinden von Eltern stehen immer wieder im Mittelpunkt medialer Aufmerksamkeit. Auch die Forschung hat sich aus unterschiedlichen Blickwinkeln mit dem Wohlbefinden und mit Belastungsaspekten im Rahmen von Elternschaft auseinandergesetzt, vor allem mit Elterneffekten (z. B. Effekten elterlicher Belastung oder von Paarkonflikten) auf das Kind. Aufgrund der Interdisziplinarität der Forschungsbefunde stehen diese teilweise unverknüpft nebeneinander. Das Ziel der vorliegenden Arbeit ist es daher, die Rolle des Kindes für das Wohlbefinden von Eltern auf systematische Weise theorie- und datenbasiert zu betrachten um herauszufinden, unter welchen Umständen oder in welchen Lebenssituationen das Kind einen wichtigen Ausgangspunkt für das Wohlbefinden der Eltern darstellen kann.
Extremal metrics on the total space of destabilising test configurations
Authors: Sektnan Lars Martin , Spotti Cristiano 
Published: March 2023

AbstractWe construct extremal metrics on the total space of certain destabilising test configurations for strictly semistable Kähler manifolds. This produces infinitely many new examples of manifolds admitting extremal Kähler metrics. It also shows for such metrics a new phenomenon of jumping of the complex structure along fibres.
Automatic tree detection and attribute characterization using portable terrestrial lidar
Authors: Solares-Canal Ana , Alonso Laura , Picos Juan , Armesto Julia 
Published: March 2023

Abstract
Key message
This study details a methodology to automatically detect the positions of and dasometric information about individual Eucalyptus trees from a point cloud acquired with a portable LiDAR system.

Abstract
Currently, the implementation of portable laser scanners (PLS) in forest inventories is being studied, since they allow for significantly reduced field-work time and costs when compared to the traditional inventory methods and other LiDAR systems. However, it has been shown that their operability and efficiency are dependent upon the species assessed, and therefore, there is a need for more research assessing different types of stands and species. Additionally, a few studies have been conducted in Eucalyptus stands, one of the tree genus that is most commonly planted around the world. In this study, a PLS system was tested in a Eucalyptus globulus stand to obtain different metrics of individual trees. An automatic methodology to obtain inventory data (individual tree positions, DBH, diameter at different heights, and height of individual trees) was developed using public domain software. The results were compared to results obtained with a static terrestrial laser scanner (TLS). The methodology was able to identify 100% of the trees present in the stand in both the PLS and TLS point clouds. For the PLS point cloud, the RMSE of the DBH obtained was 0.0716, and for the TLS point cloud, it was 0.176. The RMSE for height for the PLS point cloud was 3.415 m, while for the PLS point cloud, it was 10.712 m. This study demonstrates the applicability of PLS systems for the estimation of the metrics of individual trees in adult Eucalyptus globulus stands.
Understanding the influence of news on society decision making: application to economic policy uncertainty
Authors: Trust Paul , Zahran Ahmed , Minghim Rosane 
Published: March 2023

AbstractThe abundance of digital documents offers a valuable chance to gain insights into public opinion, social structure, and dynamics. However, the scale and volume of these digital collections makes manual analysis approaches extremely costly and not scalable. In this paper, we study the potential of using automated methods from natural language processing and machine learning, in particular weak supervision strategies, to understand how news influence decision making in society. Besides proposing a weak supervision solution for the task, which replaces manual labeling to a certain extent, we propose an improvement of a recently published economic index. This index is known as economic policy uncertainty (EPU) index and has been shown to correlate to indicators such as firm investment, employment, and excess market returns. In summary, in this paper, we present an automated data efficient approach based on weak supervision and deep learning (BERT + WS) for identification of news articles about economical uncertainty and adapt the calculation of EPU to the proposed strategy. Experimental results reveal that our approach (BERT + WS) improves over the baseline method centered in keyword search, which is currently used to construct the EPU index. The improvement is over 20 points in precision, reducing the false positive rate typical to the use of keywords.
Using the COM-B model to identify barriers to and facilitators of evidence-based nurse urine-culture practices
Authors: Advani Sonali D. , Winters Ali , Turner Nicholas A. , Smith Becky A. , Seidelman Jessica , Schmader Kenneth , Anderson Deverick J. , Reynolds Staci S. 
Published: March 2023

Abstract
Our surveys of nurses modeled after the Capability, Opportunity, and Motivation Model of Behavior (COM-B model) revealed that opportunity and motivation factors heavily influence urine-culture practices (behavior), in addition to knowledge (capability). Understanding these barriers is a critical step towards implementing targeted interventions to improving urine-culture practices.
A Review of the Effectiveness of the Nigerian Whistleblowing Stopgap Policy of 2016 and the Whistleblower Protection Bill of 2019
Authors: Ojobo Ejemen 
Published: March 2023

AbstractThe act of whistleblowing is not common in Nigeria; this can be attributed to the cultural norms of Nigerian society where deference is paid to those in positions of power and it is often viewed as taboo to speak up against them. This problem of not speaking up is further compounded by the lack of robust whistleblowing legislation which protects whistleblowers from reprisals. The need to protect whistleblowers was brought to the forefront after the implementation in 2016 of the Nigerian stopgap policy on whistleblowing, leading to the Whistleblower Protection Bill proposed in 2019, legislation that seeks to provide wider protection to whistleblowers. This article examines this bill, identifying its limitations; it does not rehash previous scholarly debates about whether incentives are necessary, but rather focuses on bringing the Nigerian perspective to the fore, thus contributing to the existing literature in this area.