bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nota da Editora
Authors: Cardoso Squeff Tatiana 
Published: July 2023

Apresenta a edição n. 2 do vol. 50 da Revista da Faculdade de Direito da Universidade Federal de Uberlândia, tecendo importantes comentários inspirados do pensamento de Gabriel Garcia Márquez acerca do acesso ao conhecimento diante do cenário global cada vez mais tecnológico, que fomenta o digital divide e faz brotar novas expressões coloniais, como a colonialidade digital. Assim, a edição é composta por sete seções, contemplando 27 artigos científicos assinados por 50 pesquisadores diferentes, vinculados a instituições situadas em 12 estados da federação (GO, DF, MG, MS, PE, PR, RJ, RN, RO, RS, SC e SP), além de instituições do exterior, nomeadamente Bolívia, Espanha, Suíça e País Basco. Ademais, este número igualmente contempla 2 book reviews, 1 comentário de jurisprudência, 1 relatório e 2 anais de eventos acadêmicos realizados com fomento da Revista, perfazendo 950 páginas e 34 arquivos!
THE STRONG AND STABLE UPWELLING AND DOWNWELLING REGIONS IN THE ECMAN LAYER OF THE SOUTH CHINA SEA
Authors: Lanh Vo Van , Son Tong Phuoc Hoang , Tuan Nguyen Van 
Published: July 2023

On the basis of distribution of curl (τ/f) computed by the means monthly data of wind and relationship between the curl (τ/f) with the vertical velocity W [equation (5)], the regions of upwelling [Rot(τ/f) > 0, W < 0] and downwelling [Rot(τ/f) < 0, W > 0] in the Ecman layer of South China Sea were determined. The results indicates that the upwelling and downwelling phenomena are occurred almost everywhere in the sea, but the most strong (/W/ ≥ 10-3 cm/s) and stale ones in the following locations: 1. Very strong upwelling in he Southern Central Vietnam coastal and shelf waters during South West Monsoon (Fig. 2). The hydrological analysis indicate that in the centre of the upwelling, the /W/ can reach to 10-1 – 10-2 cm/s, the water temperature anomaly - to -3 ÷ -50C and salinity anomaly - to +1,2%o at the depths of 50 - 100 m. 2. The strong upwelling in the region North West and South West of Luzon island during North East Monsoon, when the water temperature anomaly can reach to -30C and salinity - to +1%o at the depths of 50 – 100 m (Fig. 1). 3. The strong downwelling in the Southern Central Vietnam coastal and shelf waters and in the region South West of Taiwan during North East Monsoon (Fig. 1). τ is the wind stress, f is the Coriolic parameter, W is the vertical velocity.
JOINT VIETNAMESE - RUSSIAN RESEARCHES IN MARINE BIOLOGY DURING 1980-2007
Authors: An Nguyen Tac , Dautova T. N. 
Published: July 2023

The main programs of cooperation between IMB FESC AS USSR and Institute of Marine Researches belonging to the National Centre of Natural Science and Technology in Vietnam for the period of 1980 - 2000 were established asfollows: - Tropical littoral ecosystems (coral reef and the intertidal area: biodiversity and productivity). - Biological basis for mariculture of algae and invertebrates. - Biochemistry and chemislly ofmarine organisms. - Microelemental consistency of mass species of algae and invertebrates. Co-researches in the 21th century are being held due to agreements of co-activities between IMB RAS and Scientific Institutes of VAST Together with Institute of Oceanography, Institute of Materials and Institute of Marine Environment and Resources. Institute of Natural Combinations’ Chemistty, of VAST, there are some main cooperative projects: - Due to increasing influence of anthropogenic stress if was concluded that importan task is to use macrophytes and reef building corals as indicators of anthropogenic pollution. Another idea - to estimate productive resources of marine algae, grasses and reef building corals, their realization in nature and cultivation. - Research in spheres of biodiversity of Vietnamese open waters. - Study of bioactive substances of marine animals and algae. - Study of species diversity and distribution of marine plants in southern and northern regions of Vietnam.
A novel type of facultative and plasminogen independent thrombolytic enzyme from the ancient marine organism, Sipunculus nudus
Authors: Ma Guoxing , tang mingqing , Xu Chun-Yan , Yang Hui , Lin Hongjun , Bian Chao , Hu Chengjia , Lu Meiling , Chen Lei , Jie Wen-cai , Yue Zhen , Jian Jianbo , Sun Yuqing , Zhou Jingjing , Huang Yiwen , Li Zhaofa , Cai Shuangfeng , Wu Yaqing , Yang Kexin , Yan Hui , Xiong Yanan , Zhao Yonggang , Lv Zhimin , Xu Xiaoming , Liu Chuang , Xin Pengliang , Ye Lichao , Cuil Xiuling , Shi Qiong , Chen Xi , XU Ruian 
Published: July 2023

Abstract
Thrombotic diseases have become a leading threat to global health, especially in the post-COVID-19 era. Current thrombolytic drugs are highly dependent on the activation of the human plasminogen. Herein we disclose a novel facultative and plasminogen independent thrombolytic enzyme (snFPITE) from Sipunculus nudus, which could completely dissolve fibrin(ogen) into ultra-small molecule fragments without leaving any undegradable D-dimer. Furthermore, it cleaves the plasminogen to form a new fibrinolytic-active agent (Flaa) rather than the conventional plasmin. Mechanistically, snFPITE activates the plasminogen and degrades fibrin(ogen) at multiple cleavage sites, and this plasminogen activation and fibrin(ogen) degradation are inhibited by plasminogen activator inhibitor 1 and α2-antiplasmin through a unique competitive inhibition mechanism. On the other hand, up to 29 snFPITE candidate sequences have been identified by mass spectroscopy, molecular cloning and genome sequencing, including 10 of which that have been functionally verified. This novel thrombolytic enzyme pool might be valuable for the rapid development of powerful and efficient thrombolytic drugs in the near future.
Exploring Snake Robot Motion Control: A VR-Enhanced Approach for Studying the MPC Algorithm
Authors: Sibilska-Mroziewicz Anna , Mozaryn Jakub , Ordys Andrzej , Hameed Ayesha , Abadi Ali Soltani Sharif , Sibilski Krzysztof 
Published: July 2023

Abstract
This study focuses on enhancing control strategies and locomotion capabilities for underactuated snake robots. A 10-segment underactuated snake robot with 9 Degrees of Freedom (DOF) is modelled and controlled using Model Predictive Control (MPC). MATLAB is utilized to implement the snake robot model and various control algorithms. The simulation results are then integrated into a Virtual Reality (VR) application to visualize the motion of the snake robot. The VR scene generates an animated representation of the snake robot's segments, along with selected physical parameters such as segment velocities, heading angle, and "ghost robots" - predicted positions of the snake robot, along the prediction horizon, calculated by the MPC algorithm. The results demonstrate improved performance and agility of the snake robot by implementing advanced control strategies. The examined strategies enable the robot to navigate in challenging environments even with joint malfunctions.
Analysis of the clinical value of postoperative circulating tumor DNA (ctDNA) within the first month for resected colorectal cancer in a real-world.
Authors: feng zhen , Sun Zhiwei , Song Yang , zhang yu , hai yanru , Zheng Mengge , wu zoey , ren shuangyi , zhang qianshi 
Published: July 2023

Abstract
Purpose
Analysis of the clinical value of postoperative circulating tumor DNA (ctDNA) within the first month for resected colorectal cancer in a real-world.
Methods
In this longitudinal cohort study, 42 resectable CRC patients with stage I-III were enrolled and treated per standard of care. Tumor tissues (n = 42) and serial plasma samples (n = 161) were collected and detected with massively parallel sequencing to evaluate somatic variants. Recurrence monitoring during approximately 2 years of follow-up period was performed. Survival analysis was performed by the Kaplan-Meier method, based on the Log-Rank test.
Results
Mutation profiling in paired baseline tissues and plasma samples demonstrated a good concordance (P<0.01). Serial analysis of ctDNA profiling indicated mutation status of CRC-related driver genes and DNA damage repair pathway genes in this cohort were tightly correlated with clinical recurrence. Longitudinal ctDNA detection revealed ctDNA positivity was closely associated with an inferior recurrence-free survival in the whole course of pre- or postoperation, especially ctDNA status in first month postoperatively (P = 0.037). Furthermore, ctDNA status in first month post-operation was the strongest independent risk factor for predicting recurrence after adjusting for clinicopathologic indexes in the multivariate analysis (HR = 24; 95% CI, 2.168–265.8; P = 0.01). Combination of postoperative ctDNA status in 1 month with clinical risk stratification based on clinicopathologic characteristics also significantly improved classification of prognosis (P = 0.008). CtDNA predicted recurrence with an average lead time of 5 months compared with CT imaging.
Conclusion
CtDNA within the first month is great importance to hint prognosis and predict response to adjuvant therapy.
MANUSIA SEMPURNA MENURUT AL-JILI
Authors: Dirhamzah Dirhamzah 
Published: July 2023

ABSTRACT This article discusses the concept of "Insan Kamil" according to Al-Jili. The concept of his thought is written in his book entitled "al-Insan al-Kamil fi Ma'rifat-I 'l-awãkhir wa' l-Awã'il". A perfect human being according to Al-Jili is a human being the mirror of God or a human being a copy of God. In al-Jîlî's view the most perfect tajalli container of god and none other is Nur Muhammad, according to him Nur Muhammad has existed since before this universe existed. Nur Muhammad moved from one generation to the next in various forms of prophets, starting from the Prophet Adam As to the closing Prophet, then moved to the guardians and ending with the closing guardian (khatam auliyâ), namely Isa as who will descend at the end time. Such is the process of tajalli (self -appearance) of Allah in the universe. His most perfect tajalli container is a perfect human being in the form of the Prophet Muhammad saw. Because the Prophet Muhammad is a human being who is considered to have reached a degree of perfection in his life. Keywords: Al-Jili, Insan Kamil, Nur Muhammad ABSTRAK Artikel ini membahas tentang konsep “Insan Kamil’ menurut pandangan Al-Jili. Konsep pemikirannya tersebut ditulis dalam bukunya yang berjudul “al-Insan al-Kamil fi Ma’rifat-I ‘l-awãkhir wa ‘l-Awã’il”. Insan kamil menurut Al-Jili adalah manusia cermin tuhan atau manusia copy (nuskah) tuhan. Dalam pandangan al-Jîlî wadah tajalli tuhan yang paling sempurna dan tidak ada yang lain adalah Nur Muhammad, menurutnya Nur Muhammad telah ada sejak sebelum alam ini ada. Nur Muhammad berpindah-pindah dari satu generasi ke generasi berikutnya dalam berbagai bentuk para nabi, mulai dari Nabi Adam As hingga pada Nabi penutup, kemudian berpindah kepada para wali dan berakhir pada wali penutup (khatam auliyâ), yaitu Isa as yang akan turun pada akhir zaman. Demikian proses tajalli (penampakan diri) Allah pada alam semesta. Wadah tajalli-Nya yang paling sempurna adalah insan kamil dalam wujud Nabi Muhammad saw. Karena Nabi Muhammad-lah manusia yang dinilai telah mencapai derajat kesempurnaan dalam hidupnya.
Sosialisasi rintisan pengembangan desa wisata kebugaran kelurahan Canden kabupaten Bantul D.I Yogyakarta
Authors: Agustin Helfi , Hidayat M. Syamsu , Wardiyanta Wardiyanta , Adhilla Fitroh 
Published: July 2023

Canden, a village in the Bantul Regency, is one of the tourism settlements with the potential to develop. The village of Canden comprises 15 hamlets, one of which is Kiringan, recognized as a hub for conventional herbal medicine. This hamlet is home to at least 110 herbal medicine vendors. This community service project aimed to make it easier for the town of Canden to thrive as a tourism destination, starting with the potential of herbal medicine as the foundation of wellness travel. This community service approach was participatory rural appraissal using focus group discussion with community, tourism management, head of the tourism office, public health center, university, and so on. This community service was carried out smoothly and the results were obtained in the form of community mapping and identification of needs in the development of fitness tourism villages.
The possibilities of game dialog programs for teaching the solution of typical tasks of the "Programming" section of the school informatics course
Authors: Markelov V. K. , Zavyalova O. A. 
Published: July 2023

Today, not enough attention is paid to teaching programming in schools, as it causes many difficulties for students associated with a misunderstanding of the abstract and difficult to assimilate new material. At the same time, a weak level of motivation to study and, in the future, to teach the section "Programming" is one of the problems of training future informatics teachers. As a means of motivation for both students and future informatics teachers, game dialogue programs (games in which the player enters into a dialogue with the computer) can be used. Such programs can be used by teachers to develop students' skills in solving typical problems in the "Programming" section.The article discusses the possibilities of using various types of game dialogue programs (text quests, games with random numbers, dice, bulls and cows) for learning to solve typical problems in the "Programming" section. In particular, these games can be used in the study of data processing algorithms using branches and loops, algorithms for finding the maximum and minimum, algorithms for extracting digits from a natural number. At the same time, it should be noted that these programs can be adapted for learning to solve typical problems of the "Programming" section based on other educational programming languages, such as Pascal, Java, C++, etc.
THE EFFECT OF DIFFERENT INTENSITY OF SESSIONS ON THE OOCYTES RETRIEVAL FROM LIVED COWS
Authors: Чинаров Р.Ю. , Луканина В.А. , Сингина Г.Н. 
Published: July 2023

В статье рассмотрено влияние различной интенсивности сессий на результативность прижизненной УЗИ-ассистированной пункции фолликулов у коров (OPU). Исследования проводили на телках-донорах симментальской породы (n=4). Была выполнена 91 сессия OPU с интервалами между ними 3, 4, 7 и 8 дней. Наибольшая результативность в отношении числа визуализированных фолликулов наблюдалась при проведении их аспирации с интервалом 3 дня. В среднем за сессию было аспирировано 15,85 фолликула, что, соответственно, на 5,44 (P≤0,001) и 5,08 (P≤0,001) фолликула превышало значения данного показателя при проведении пункций с интервалом 4 и 7 дней. Не наблюдалось достоверное влияние различной интенсивности сессий на степень извлечения ооцитов: значения данного показателя варьировали от 41,00 до 46,06%. При проведении OPU с интервалом 3 дня в среднем за сессию было получено 7,30 ооцит-кумулюсного комплекса (ОКК), что на 2,92 (P≤0,001), 2,36 (P≤0,001) и 2,17 ОКК (P≤0,01) превышало значения показателей, достигнутых в группах телок-доноров, подвергавшихся пункции фолликулов с интервалом 4, 7 и 8 дней. Учитывая, что доли пригодных ОКК при проведении сессий с интервалом 3—7 дней существенно не различались, повышение интенсивности сессий OPU (1 раз в 3 дня) позволяет получать больше ооцит-кумулюсных комплексов хорошего качества за определенный период времени по сравнению с проведением сессий с большим интервалом — 4—8 дней.
The effect of different intensity of sessions on the efficiency of ultrasound-assisted follicles puncture (OPU) in lived cows is considered. The studies were carried out on donor heifers of the Simmental breed (n=4). A total of 91 OPU sessions were performed with an interval between sessions of 3, 4, 7 and 8 days. The greatest efficiency in relation to the number of visualized follicles was observed during follicle aspiration with an interval of 3 days. On average, 15.85 follicles were aspirated during one session, which exceeded by 5.44 (P≤0.001) and 5.08 (P≤0.001) follicles the values of this indices observed at intervals of 4 and 7 days, respectively. We did not find a significant effect of different session intensity on the oocyte retrieval rate: the values of this indices ranged from 41.00 to 46.06%. During OPU with an interval of 3 days, we obtained an average of 7.30 cumulus-oocyte complexes (COCs) per session, which was 2.92 (P≤0.001), 2.36 (P≤0.001) and 2.17 (P≤0.01) COCs higher than the values achieved in the groups of donor heifers undergoing follicle puncture at intervals of 4, 7 and 8 days. Considering that the rate of suitable COCs during sessions with an interval of 3—7 days did not differ significantly, increasing the intensity of OPU sessions (once every three days) allows to get more cumulus-oocyte complexes of good quality for a certain period of time compared with sessions with a greater interval of 4—8 days.
APPLICATION OF INTESTINAL LAVAGE FOR CORRECTION OF PROTEOLYTIC ACTIVITY IN ACUTE INTESTINAL OBSTRUCTION
Authors: Boyko V. V. , Merkulov A. A. , Shevchenko O. M. , Beloded E. A. 
Published: July 2023

Summary. The aim of the work is to improve the results of treatment of patients with acute adhesive intestinal obstruction in the postoperative period by correcting the proteolytic activity of small intestinal contents
Materials and methods. 62 patients were operated on for acute adhesive intestinal obstruction. All patients underwent nasogastrointestinal intubation with aspiration of intestinal contents and subsequent prolonged intestinal decompression.
62 patients were operated on for acute adhesive intestinal obstruction, which were divided into 2 groups. In group 1 (n = 39), after dissection of adhesions and resection of the small intestine area (if necessary), intestinal contents were evacuated and the small intestine was washed with saline sodium chloride solution. In the 2nd group (n = 23), 200.0 ml of 5 % α-aminocaproic acid was additionally administered with 30-minute probe compression on days 1, 2 and 3 of the postoperative period 2 times a day with an interval of 12 hours.
Research results. In the second group, after intestinal lavage with α-aminocapronic acid, a decrease in total proteolytic activity was observed both in the contents of the small intestine and in blood serum.
Conclusions. The use of intestinal lavage with the use of aminocaproic acid leads to a faster normalization of total proteolytic activity both in the contents of the small intestine and in the blood serum, to a decrease in the α1-antiproteinase inhibitor, proteolysis index, and also contributes to an earlier elimination of intestinal paresis.
IDENTIFICATION OF ANTIFUNGAL COMPOUNDS FROM LEAF EXTRACT OF EUCALYPTUS CITRIODORA AGAINST ASCOCHYTA RABIEI
Authors: A. Javaid  
Published: July 2023

Ascochyta rabiei (Pass.) Lab. is a highly destructive pathogen of chickpea. In thisstudy, leaf extract of Eucalyptus citriodora was assessed against this pathogen. Bioassays withmethanolic extract (0, 05, 1.0, 1.5, …, 4.0%) extract revealed the remarkable antifungal potential ofleaf extract where 69–94% reduction in biomass of A. rabiei was recorded. Chloroform fraction of thisextract was separated by partitioning the extract in a separating funnel. Using a solvent system ofchloroform: n-hexane (20:80), three compounds were detected on TLC plate which were separatedthrough preparative TLC and purified on HPLC. GC-MS of the purified compounds lead to theidentification of 3-cyclohexene- 1-ol, 4-methyl-1-(1-methylethyl)- (1), 1-cyclohexene- 1carboxaldehyde,4-(1-methylethyl)- (2) and eucalyptol (3) that might caused antifungal activity of the extract.
Numeric estimates of the principal eigenvalue of the p-Laplacian using interval arithmetic
Authors: Benedikt Jiri , Pulpan Jan 
Published: July 2023

We present a numerical algorithm for computing rigorous upper and lower estimates of the principal eigenvalue of the p-Laplacian. To control all possible errors including the rounding errors of the computer arithmetic, we use the interval arithmetic. We implement our algorithm in the Julia programming language using IntervalArithmetic.jl package [12].
See also https://ejde.math.txstate.edu/special/02/b3/abstr.html
Tinjauan Yuridis tentang Diakonia dalam Gereja
Authors: Jehaut Rikardus 
Published: July 2023

This article focuses on juridical analysis of the ministry of charity (diakonia) in the light of Codex Iuris Canonici 1983 and some of magisterial teaching such as Deus caritas est and Intima Ecclesiae natura (on the church’s deepest nature). Relying heavily on these Church’s documents, this article seeks to offer canonical insights concerning four points of particular interest: first, the ministry of charity (diakonia) is a constitutive element of the Church’s mission and an indispensable expression of her very being; second, by baptism, all the faithful have the right and responsibilities to devote themselves personally to the service of charity; third, the exercise of the ministry of charity requires organization. The community of the faithful and every faithful has the right, ad normam iuris, to form charitable organisations or create foundations to fund concrete charitable initiatives; fourth, the ministry of charity is directly connected to the Episcopal ministry. Indeed, the bishop is the one primary responsible for that ministry. He has a role in supervising and coordinating works of charity. This article argues that in the area of ministry of charity, diocesan bishop play a pivotal role. He must show a concrete and visible commitment, ensuring that the ministry of charity is to be the chief concern of the particular Church, promoting communion and dialogue among the various agencies as well as keeping the
Leukocyte telomere length predicts subsequent infectious morbidity among Colombian schoolchildren
Authors: Lee Gwenyth O. , Mora‐Plazas Mercedes , Marín Constanza , Villamor Eduardo 
Published: July 2023

AbstractObjectiveTelomere length (TL) attrition is related to chronic disease risk. However, less is known on whether TL predicts infectious outcomes, especially in childhood. We examined whether leukocyte TL (LTL) was associated with subsequent infectious morbidity in schoolchildren.MethodsWe assessed LTL in 717 Colombian children 5–12 years‐old at the beginning of a school year and followed them through the year for daily occurrence of common infection symptoms and doctor visits. We estimated adjusted incidence rate ratios (IRR) with 95% confidence intervals (CI) of gastrointestinal and respiratory syndromes for quartiles of standardized LTL Z score and per unit LTL Z score.ResultsA longer LTL was associated with increased incidence of all infectious morbidity syndromes considered. Adjusted IRR (95% CI) per unit LTL Z score were 1.55 (1.20, 2.00) for diarrhea with vomiting, 1.34 (1.13, 1.60) for cough with fever, 1.70 (1.28, 2.28) for ear infection, and 1.66 (1.36, 2.02) for doctor visits with symptoms.ConclusionsLonger LTL is related to increased incidence of common infectious morbidities in middle childhood.