bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Intervention to Increase Condom Use Among Users of Sexually Transmitted Infection Self-sampling Websites (Wrapped): Protocol for a Randomized Controlled Feasibility Trial
Authors: Newby Katie , Kwah Kayleigh , Schumacher Lauren , Crutzen Rik , Bailey Julia V , Jackson Louise J , Bremner Stephen , Brown Katherine E 
Published: February 2023

Background
Reducing the rates of sexually transmitted infections (STIs) among young people is a public health priority. The best way to avoid STIs from penetrative sex is to use a condom, but young people report inconsistent use. A missed opportunity to intervene to increase condom use is when young people access self-sampling kits for STIs through the internet. The potential of this opportunity is enhanced by the increasing numbers of young people being tested through this route every year in England. Hence, in a cocreation by young people, stakeholders, and researchers, Wrapped was developed––a fully automated, multicomponent, and interactive digital behavior change intervention developed for users of STI self-sampling websites, who are aged 16-24 years.

Objective
This paper is a protocol for a feasibility randomized controlled trial (fRCT). The fRCT seeks to establish whether it is feasible to run a randomized controlled trial to test the effectiveness and cost-effectiveness of Wrapped. Wrapped aims to reduce the incidence of STIs through increasing correct and consistent use of condoms among users of STI self-sampling websites, who are aged 16-24 years.

Methods
A 2-arm parallel-group randomized fRCT of Wrapped plus usual care, compared to usual care only (basic information on STIs and condom use), with a nested qualitative study. A minimum of 230 participants (aged 16-24 years) are recruited from an existing chlamydia self-sampling website. Participants are randomized into 1 of 2 parallel groups (1:1 allocation). Primary outcomes are the percentage of users recruited to the fRCT and the percentage of randomized participants who return a chlamydia self-sampling kit at month 12. Additionally, besides chlamydia positivity based on biological samples, surveys at baseline, month 3, month 6, and month 12, are used to assess condom use attitude, behavioral capability, self-efficacy, and intention, along with details of any partnered sexual activity and condom use, and health economic data. Nested qualitative interviews with trial participants are used to gain insight into the factors affecting recruitment and attrition.

Results
Recruitment to the fRCT began in March 2021 and was completed in October 2021. Data collection was completed in December 2022.

Conclusions
This feasibility study will provide data to inform the design of a future-definitive trial. This work is timely given a rapid rise in the use of internet testing for STIs and the sustained high levels of STIs among young people.

Trial Registration
ISRCTN Registry ISRCTN17478654; http://www.isrctn.com/ISRCTN17478654

International Registered Report Identifier (IRRID)
DERR1-10.2196/43645
Prediction Models for Sleep Quality Among College Students During the COVID-19 Outbreak: Cross-sectional Study Based on the Internet New Media
Authors: Zheng Wanyu , Chen Qingquan , Yao Ling , Zhuang Jiajing , Huang Jiewei , Hu Yiming , Yu Shaoyang , Chen Tebin , Wei Nan , Zeng Yifu , Zhang Yixiang , Fan Chunmei , Wang Youjuan 
Published: February 2023

Background
COVID-19 has been reported to affect the sleep quality of Chinese residents; however, the epidemic’s effects on the sleep quality of college students during closed-loop management remain unclear, and a screening tool is lacking.

Objective
This study aimed to understand the sleep quality of college students in Fujian Province during the epidemic and determine sensitive variables, in order to develop an efficient prediction model for the early screening of sleep problems in college students.

Methods
From April 5 to 16, 2022, a cross-sectional internet-based survey was conducted. The Pittsburgh Sleep Quality Index (PSQI) scale, a self-designed general data questionnaire, and the sleep quality influencing factor questionnaire were used to understand the sleep quality of respondents in the previous month. A chi-square test and a multivariate unconditioned logistic regression analysis were performed, and influencing factors obtained were applied to develop prediction models. The data were divided into a training-testing set (n=14,451, 70%) and an independent validation set (n=6194, 30%) by stratified sampling. Four models using logistic regression, an artificial neural network, random forest, and naïve Bayes were developed and validated.

Results
In total, 20,645 subjects were included in this survey, with a mean global PSQI score of 6.02 (SD 3.112). The sleep disturbance rate was 28.9% (n=5972, defined as a global PSQI score >7 points). A total of 11 variables related to sleep quality were taken as parameters of the prediction models, including age, gender, residence, specialty, respiratory history, coffee consumption, stay up, long hours on the internet, sudden changes, fears of infection, and impatient closed-loop management. Among the generated models, the artificial neural network model proved to be the best, with an area under curve, accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of 0.713, 73.52%, 25.51%, 92.58%, 57.71%, and 75.79%, respectively. It is noteworthy that the logistic regression, random forest, and naive Bayes models achieved high specificities of 94.41%, 94.77%, and 86.40%, respectively.

Conclusions
The COVID-19 containment measures affected the sleep quality of college students on multiple levels, indicating that it is desiderate to provide targeted university management and social support. The artificial neural network model has presented excellent predictive efficiency and is favorable for implementing measures earlier in order to improve present conditions.
Assessment of thin bony structures using cone-beam computed tomography
Authors: Lennholm Camilla , Westerlund Anna , Lund Henrik 
Published: February 2023

ABSTRACTObjectivesTo investigate the validity and reliability of marginal bone level measurements on cone-beam computed tomography (CBCT) images of thin bony structures using various reconstruction techniques, two image resolutions, and two viewing modes.Materials and MethodsCBCT and histologic measurements of the buccal and lingual aspects of 16 anterior mandibular teeth from 6 human specimens were compared. Multiplanar (MPR) and three-dimensional (3D) reconstructions, standard and high resolutions, and gray scale and inverted gray scale viewing modes were assessed.ResultsValidity of radiologic and histologic comparisons were highest using the standard protocol, MPR, and the inverted gray scale viewing mode (mean difference = 0.02 mm) and lowest using a high-resolution protocol and 3D-rendered images (mean difference = 1.10 mm). Mean differences were significant (P &lt; .05) at the lingual surfaces for both reconstructions, viewing modes (MPR windows), and resolutions.ConclusionsVarying the reconstruction technique and viewing mode does not improve the observer's ability to visualize thin bony structures in the anterior mandibular region. The use of 3D-reconstructed images should be avoided when thin cortical borders are suspected. The small difference when using a high-resolution protocol is unjustified due to the higher radiation dose required. Previous studies have focused on technical parameters; the present study explores the next link in the imaging chain.
PENERAPAN LAYANAN MEDIASI UNTUK MENGURANGI PERKELAHIAN ANTAR SISWA SMP NEGERI 5 PERCUT SEI TUAN
Authors: Hasni Erna 
Published: February 2023

Abstract: Application of Mediation Services to Reduce Fighting Between Students of SMP Negeri 5 Percut Sei Tuan. The purpose of this study is to reduce fights between students through the application of mediation services and to find out the enhancement of the skills of the BK Guidance teacher conducting mediation services. The study was conducted at SMP Negeri 5 Percut Sei Tuan starting from early February 2017 to June 2017 with two cycles of action. The subjects in this study were 10 students from SMP Negeri 5 Percut Sei Tuan who were involved in a fight in the school environment. The results showed that the application of mediation services to overcome fights in SMP Negeri 5 Percut Sei Tuan can reduce the level of fighting among students.Keywords: service, mediation, fightingAbstrak: Penerapan Layanan Mediasi untuk Mengurangi Perkelahian Antar Siswa SMP Negeri 5 Percut Sei Tuan. Tujuan penelitian ini adalah untuk mengurangi perkelahian antar siswa melalui penerapan layanan mediasi dan untuk mengetahui peningkatan keterampilan Guru BK melakukan layanan mediasi. Penelitian dilakukan di SMP Negeri 5 Percut Sei Tuan mulai dari awal Februari 2017 sampai Juni 2017 dengan dua siklus tindakan. Subjek dalam penelitian ini adalah siswa-siswi SMP Negeri 5 Percut Sei Tuan berjumlah 10 orang yang terlibat dalam perkelahian di lingkungan sekolah. Hasil penelitian menunjukkan bahwa penerapan layanan mediasi untuk mengatasi perkelahian di SMP Negeri 5 Percut Sei Tuan dapat mengurangi tingkat perkelahian antar siswa.Kata kunci: layanan, mediasi, perkelahian
MENINGKATKAN HASIL BELAJAR SISWA PADA MATA PELAJARAN IPA DENGAN METODE DEMONTRASI DI KELAS VII-1 SMPN 1 PATUMBAK
Authors: Nadapdap Erika 
Published: February 2023

Abstract: Improving Student Learning Outcomes in Science Subjects Using Demonstration Methods in Class VII-1 SMPN 1 Patumbak. The purpose of this study was to determine the increase in students' science learning outcomes through the application of the Demonstration method in science subjects for Class VII-1 students of SMPN 1 Patumbak T.A 2018/2019. Student activities in the learning process of demonstrations each cycle have increased. This has a positive impact on student achievement, which can be shown by increasing the average value of students in each cycle. This can be seen from the increasingly solid understanding of students towards the material delivered by the teacher (mastery learning increases from cycles I, II, and III), namely respectively 67.57%, 78.38%, and 89.19%. In cycle III students' classical learning completeness has been achieved.Keywords: Learning Outcomes, Demonstration Method, Science LearningAbstrak: Meningkatkan Hasil Belajar Siswa Pada Mata Pelajaran IPA Dengan Metode Demonstrasi Di Kelas VII-1 SMPN 1 Patumbak. Tujuan penelitian ini adalah untuk mengetahui peningkatan hasil belajar IPA siswa melalui penerapan metode Demonstrasi pada mata pelajaran IPA siswa Kelas VII-1 SMPN 1 Patumbak T.A 2018/2019. Aktivitas siswa dalam proses pembelajaran demonstrasi setiap siklus mengalami peningkatan. Hal ini berdampak positif terhadap prestasi belajar siswa yaitu dapat ditunjukkan dengan meningkatnya nilai rata-rata siswa pada setiap siklus. Hal ini dapat dilihat dari semakin mantapnya pemahaman siswa terhadap materi yang disampaikan guru (ketuntasan belajar meningkat dari siklus I, II, dan III) yaitu masing-masing 67,57%, 78,38%, dan 89,19%. Pada siklus III ketuntasan belajar siswa secara klasikal telah tercapai.Kata kunci: Hasil belajar, Metode Demonstrasi, Pembelajaran IPA
ANALISIS KETERAMPILAN GURU SEKOLAH DASAR DALAM MENERAPKAN VARIASI PEMBELAJARAN
Authors: Pratiwi Cerianing Putri , Ediyono Suryo 
Published: February 2023

Abstract: Analysis of Elementary School Teacher Skills in Applying Learning Variations. This study aims to determine the skills of primary school teachers in applying variations of learning. This research is a descriptive qualitative research. This research was conducted in Purwosari Elementary School. The subjects used in this study were 5th grade teachers. Data collection techniques used were observation, documentation, and interviews. Data analysis techniques using interactive model data analysis techniques in the form of data reduction, data presentation and drawing conclusions. The results of this study are Purwosari elementary school teachers have implemented a variety of learning in accordance with the planned implementation of learning.Keywords: Teacher Skills, Learning VariationsAbstrak: Analisis Keterampilan Guru Sekolah Dasar dalam Menerapkan Variasi Pembelajaran. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan keterampilan guru SD dalam menerapkan variasi pembelajaran. Jenis penelitian ini yaitu kualitatif deskriptif.. Tempat dilaknakan penelitian yaitu di Sekolah dasar Purwosari. Subyek yang digunakan dalam penelitian ini yaitu guru kelas 5. Dalam pengumpulan data menggunakan dokumentasi, wawancara, dan observasi. Penelitian ini menggunakan teknik pengumpulan data yaitu observasi, dokumentasi, dan wawancara. Teknik analisis data yang digunakan yaitu teknik analisis data model interaktif yaitu berupa reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini yaitu guru SDN Purwosari sudah menerapkan variasi belajar yang sesuai dengan rencana pelaksanaan pembelajaran yang telah disusun.Kata Kunci : Keterampilan Guru, Variasi Pembelajaran
MENINGKATKAN HASIL BELAJAR SISWA MATA PELAJARAN BAHASA INGGRIS MELALUI PICTURE SERIES DI KELAS VIII-2SMP NEGERI 1 PATUMBAK
Authors: Herniwati Herniwati 
Published: February 2023

Abstract: Improving Student Learning Outcomes of English Subjects Through Picture Series in Class VIII-2 Middle School 1 Patumbak. The purpose of this study was to determine the extent of understanding and mastery of English subjects after the use of the use of picture series in Class VIII-2 students of SMPN 1 Patumbak 2018/2019 academic year. The research subjects were students of Class VIII-2 SMPN 1 Patumbak. The results of this study indicate that simple English learning using the applied introductory system is carried out through five stages of learning, namely (1) Introduce, (2) Second stage, Connect, (3) In the Apply stage, ( 4) The next stage is Reflect (5) Train students to describe something in the group. Keywords: English, picture series, learning outcomes Abstrak:Meningkatkan Hasil Belajar Siswa Mata PelajaranBahasa Inggris Melalui Picture Series Di Kelas VIII-2SMP Negeri 1 Patumbak.Tujuan penelitian ini adalah untuk mengetahui seberapa jauh pemahaman dan penguasaan mata pelajaran Bahasa Inggris setelah diterapkannya penggunaan picture series pada siswa siswa Kelas VIII-2 SMPN 1 Patumbak tahun pelajaran 2018/2019. Subyek penelitian adalah siswa-siswi Kelas VIII-2 SMPN 1 Patumbak. Hasil penelitian ini menunjukkan bahwa pembelajaran bahasa Inggris sederhana menggunakan sistim perkenalan terapan, dilakukan melalui lima tahapan pembelajaran yaitu (1) Introduce (Perkenalkan),(2) Tahap kedua, Connect (Hubungkan), (3) Pada tahap Apply (Terapkan),(4)Tahap berikutnya adalah Reflect (Refleksikan)(5) Melatih siswa mendiskripsikan sesuatu dalam kelompok. Kata kunci: Bahasa Inggris, picture series, hasil belajar
MENINGKATKAN HASIL BELAJAR MATEMATIKA MENGGUNAKAN MODEL INKUIRI PADA SISWA KELAS XII RPL 2 DI SMK NEGERI 7 PEKANBARU
Authors: Edwar Edwar 
Published: February 2023

Abstract: Improving Mathematics Learning Outcomes Using Inquiry Model in Class XII RPL 2 Students at SMK Negeri 7 Pekanbaru. The application of inquiry learning strategies in mathematics can improve mathematics learning outcomes of students of class XII RPL 2 SMK Negeri 7. This is indicated by the willingness and ability and activity of students to formulate problems, determine hypotheses, make students dare to ask, answer, and submit ideas . It also has activated students in the discussion process. From observations in the first and second cycles obtained, in the first cycle student learning outcomes increased from 72.73% of students achieving the KKM value and after the action in the second cycle there was an increase in student learning outcomes to 86.36% had reached the KKM value. Keywords: learning outcomes, mathematics, inquiry. Abstrak: Meningkatkan Hasil Belajar Matematika Menggunakan Model Inkuiri Pada Siswa Kelas XII RPL 2 di SMK Negeri 7 Pekanbaru. Penerapan strategi pembelajaran inkuiri pada mata pelajaran matematika dapat meningkatkan hasil belajar Matematika siswa kelas XII RPL 2 SMK Negeri 7. Hal ini ditandai dengan adanya kemauan dan kemampuan serta aktivitas siswa dalam merumuskan masalah, menentukan hipotesis, membuat siswa berani bertanya, menjawab, dan mengajukan gagasan. Selain itu juga telah mengaktifkan siswa dalam proses diskusi. Dari observasi pada siklus I dan II diperoleh, pada siklus I hasil belajar siswa meningkat dari 72.73 % siswa mencapai nilai KKM dan setelah tindakan pada siklus II ada peningkatan hasil belajar siswa menjadi 86.36 % telah mencapai nilai KKM. Kata kunci : hasil belajar, matematika, inkuiri.
DETERMINAN GRAF KNESER
Authors: Hutabarat Hanna Dewi Marina 
Published: February 2023

Abstract : Determinat of Kneser Graph. Kneser Graph is kind of simple graph with no loop and no parallel edge. Kneser Graphs could be present with matrix. In this article, we will discuss about Kneser Graph, how to present it with adjacency matrix, the determinant of the matrix. We will show that the determinant of the adjacency matrix is always zero. Using cornice determinant, the determinant of Kneser Graphs matrix could counting more easily for nxn matrix with n>4.Keywords : Kneser Graphs, Adjacency Matrix, Determinant.Abstrak : Determinan Graf Kneser. Graf Kneser merupakan graf sederhana karena tidak memiliki lup dan tidak memiliki sisi parallel. Graf Kneser dapat disajikan dalam bentuk matriks. Dalam artikel ini, akan dibahas tentang graf Kneser, penyajiannya dalam matriks ketetanggaan dan determinan dari matriks tersebut. Akan ditunjukkan bahwa determinan dari matriks ketetanggaan sebuah graf Kneser selalu nol. Pencarian determinan graf kneser menggunakan metode cornice determinan, dimana metode ini diperuntukkan untuk yang merupakan metode tercepat dalam pencarian determinan matriks. Hal ini dikarenakan graf kneser yang cenderung memiliki titik yang banyak.Kata kunci : Graf Kneser, Matriks Ketetanggaan, Determinan
PsA inhibits the development of bovine embryos through epigenetic and oxidative stress
Authors: Ma Xin , Zhan Chenglin , Ma Panpan , Jing Guo , Liyan Su , Zhang Yanlin , Jing Zhao , Liu Hongyu , Wang Jun , Lu Wenfa 
Published: February 2023

Abstract

OBJECTIVE
Histone deacetylases (HDACs) are the key regulators involved in the process of embryo development and tumor progression and are often dysregulated in numerous disordered cells, including tumor cells and somatic cell nuclear transfer (SCNT) embryos. Psammaplin A (PsA), a natural small-molecular therapeutic agent, is a potent histone deacetylase inhibitor (HDACi) that alters the regulation of histone.

SAMPLES
Approximately 2,400 bovine parthenogenetic (PA) embryos.

PROCEDURES
To investigate the effect of PsA on bovine preimplanted embryos, we analyzed the preimplantation development of PA embryos treated with PsA in this study.

RESULTS
The blastocyst formation rate of bovine PA embryos decreased sharply with an increase in concentration and duration. Furthermore, the expression of the pluripotency-related gene Nanog was decreased, and the inhibitory effects on histone deacetylases 1 (HDAC1) and DNA methylation transferase 1 (DNMT1) were observed in bovine PA embryos. The acetylation level of histone H3 lysine 9 (H3K9) was enhanced by a PsA treatment of 10 μM for 6 h, while the DNA methylation appeared unchanged. Interestingly, we also found that PsA treatment enhanced the intracellular reactive oxygen species (ROS) generation and decreased the intracellular mitochondrial membrane potential (MMP)- and superoxide dismutase 1 (SOD1)-induced oxidative stress. Our findings improve the understanding of HDAC in embryo development and provide a theoretical basis and reproduction toxicity evaluation for the application of PsA.

CLINICAL RELEVANCE
These results indicate that PsA inhibits the development of bovine preimplantation PA embryos, supplying data for the PsA clinical application concentration to avoid reproductive toxicity. In addition, the reproduction toxic effect of PsA may be modulated through increased oxidative stress on the bovine PA embryo, suggesting that PsA in combination with antioxidants, for example, melatonin, might be an effective clinical application strategy.
The natural history collections of Adam Mickiewicz University in Poznań (Poland): an outline of their history and content
Authors: Jackowiak Bogdan , Błoszyk Jerzy , Celka Zbigniew , Konwerski Szymon , Szkudlarz Piotr , Wiland-Szymańska Justyna 
Published: February 2023

Abstract
The origins of scientific nature collections in Wielkopolska (Western Poland) date back to the seventeenth century. Their development was repeatedly disrupted by major events, including two world wars fought in Poland in the twentieth century. The rescued historical collections as well as specimens of algae, plants, fungi and animals systematically collected after 1945 are now stored under optimal conditions at the Faculty of Biology of Adam Mickiewicz University in Poznań (FBAMU). The current collections include approximately 2.2 million pre-catalogued objects that document not only the biodiversity of Wielkopolska and Poland but also that of many regions of the world on all continents. Specimens included in the FBAMU are used extensively in taxonomic, biogeographic, phylogenetic, ecological and genetic studies. The collections also have significant educational value and help disseminate knowledge about biodiversity.
Digitization of and online access to data from the natural history collections of Adam Mickiewicz University in Poznań: Assumptions and implementation of the AMUNATCOLL project
Authors: Jackowiak Bogdan , Błoszyk Jerzy , Dylewska Magdalena , Nowak Maciej M. , Szkudlarz Piotr , Lawenda Marcin , Meyer Norbert 
Published: February 2023

Abstract
This paper describes a project aimed at digitizing and openly sharing the natural history collections (AMUNATCOLL) of the Faculty of Biology at Adam Mickiewicz University in Poznań (Poland). The result of this project is a database (including 2.2 million records) of plant, fungal and animal specimens, which is available online via the AMUNATCOLL portal and on the Global Biodiversity Information Facility website. This article presents selected aspects of the “life cycle” of this project, with a particular focus on its preparatory phase.
Carex brunnescens (Pers.) Poir. in Poland and in the neighbouring regions – in the past and at present
Authors: Kruk Jerzy 
Published: February 2023

Abstract
In the article, new and historical locations of Carex brunnescens (Pers.) Poir. from Poland and the neighbouring regions are described. This species was found in 2019 at two stands in north-eastern Poland – on the peaty shores of two small lakes; one situated in the Suwałki Landscape Park and the other in the Augustów Forest. Three historical records, supported by the herbarium materials, from the turn of the 19th and the 20th centuries, were situated in the Lower Vistula region (north-central Poland), i.e. in the vicinity of Kielno, Nowe and Susz. The literature data indicates the existence of many stands in the historical Eastern Prussia, one of which was situated south of the Romnicka Forest in Poland and all the others in the Kaliningrad region. Moreover, numerous incorrect reports from the Sudetes and the Carpathians were discussed. As Carex brunnescens is probably extinct at all the historical locations in the present territory of Poland, the species deserves special attention and protection at the two recently indentified stands.