bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and maturity of co-word thematic clusters: the field of linked data
Authors: Hosseini Elaheh , Taghizadeh Milani Kimiya , Sabetnasab Mohammad Shaker 
Published: July 2023

PurposeThis research aimed to visualize and analyze the co-word network and thematic clusters of the intellectual structure in the field of linked data during 1900–2021.Design/methodology/approachThis applied research employed a descriptive and analytical method, scientometric indicators, co-word techniques, and social network analysis. VOSviewer, SPSS, Python programming, and UCINet software were used for data analysis and network structure visualization.FindingsThe top ranks of the Web of Science (WOS) subject categorization belonged to various fields of computer science. Besides, the USA was the most prolific country. The keyword ontology had the highest frequency of co-occurrence. Ontology and semantic were the most frequent co-word pairs. In terms of the network structure, nine major topic clusters were identified based on co-occurrence, and 29 thematic clusters were identified based on hierarchical clustering. Comparisons between the two clustering techniques indicated that three clusters, namely semantic bioinformatics, knowledge representation, and semantic tools were in common. The most mature and mainstream thematic clusters were natural language processing techniques to boost modeling and visualization, context-aware knowledge discovery, probabilistic latent semantic analysis (PLSA), semantic tools, latent semantic indexing, web ontology language (OWL) syntax, and ontology-based deep learning.Originality/valueThis study adopted various techniques such as co-word analysis, social network analysis network structure visualization, and hierarchical clustering to represent a suitable, visual, methodical, and comprehensive perspective into linked data.
Evaluation of the microstructure and tensile strength of SiC reinforced AA1050 aluminum composite wires fabricated by friction stir extrusion process
Authors: Soleimanipour Mojtaba , Abedinzadeh Reza , Eftekhari Seyyed Ali , Heidari Ali 
Published: July 2023

In this study, the friction stir extrusion process as a new method was used to produce AA 1050 aluminum composite wires reinforced with silicon carbide (SiC) powder. The effect of process parameters on temperature (T), porosity (P) and ultimate tensile strength (UTS) was evaluated using the response surface method based on the Box-Behnken design. The input parameters included rotational speed (RS), extrusion force (EF) and reinforcement weight percentage (RF). Moreover, the microstructural evaluation of composite samples was conducted using optical microscope and scanning electron microscope. Finally, analysis of variance and regression analysis were used to obtain an appropriate model and confirm the accuracy of the results. The results showed that the temperature was increased by increasing the rotational speed to 1000 r/min and decreasing the extrusion force to 5.5 kN. Moreover, the lowest porosity value (averaged = 0.5%), and the highest tensile strength value (averaged = 153 MPa) were obtained at RS = 750 r/min, EF = 10.5 kN and RF = 3%. This can be attributed to the uniform distribution of reinforcing particles and strong interfacial bonding between SiC particles and the aluminum matrix. Also, the most effective parameter in the process was rotational speed which exhibited the greatest influence on P (53%) and UTS (41%) of composite samples. However, reinforcement weight percentage had the least effect on P (14%) and UTS (28%).
Examining the use of assistance dogs to enhance participation in everyday occupations for people with mobility challenges
Authors: Isaacson Mary , Hellman Chan 
Published: July 2023

Introduction: The impact of assistance dogs on an individual’s life is multifaceted. The occupational therapist must identify how assistance dogs enhance occupational performance and influence an individual’s life. This study aims to deepen our understanding about the benefits and challenges of assistance dogs for individuals with mobility challenges. Methods: The qualitative data analysis included codes and theme identification. Quantitative data were analyzed using descriptive analysis, including mean, standard deviation, and Cronbach’s alpha (score reliability). Results: Results indicate that the job of the assistance dog is comprehensive and complex. Assistance dogs support independence, provide hope through occupations, assist with general and client-specific needs, and provide companionship. The use of occupational therapy outcome tools to assess the benefits of service dogs adds to the body of literature. Conclusion: A service dog enhances occupational performance at home, work, school, and community. This unique study aims to deepen the understanding of the benefits and challenges of assistance dogs as an occupational therapy intervention for individuals with mobility challenges.
Refutations of Say’s Law and Dynamics of a Monetary Economy of Production
Authors: Cottin-Euziol Edouard , Piluso Nicolas 
Published: July 2023

In a monetary economy of production, Say’s law is invalid for several reasons. Based on some refutations, it is possible to state that revenues generated by the production process are structurally lower than the supply price of production, which means that firms create insufficient purchasing power to buy what they produce. Herein, we study the dynamics of such an economy and obtain two main results. First, the long-term debt level of that economy must increase during a growth phase to enable demand to grow at the same pace as supply. Second, because of the repayment of this debt, the gap between supply and net revenues generated by the production process widens along a growth phase. JEL Classification: E12, E2, E30, E42, G21
The Profitability Puzzle of Digital Labor Platforms
Authors: Li Zhongjin , Qi Hao 
Published: July 2023

By examining digital labor platforms that connect customers with gig workers, we attempt to solve the puzzle concerning why these labor platforms, such as ride-hailing companies and food delivery companies, continue to suffer weak profitability even though they promise a more efficient way to mobilize and utilize the platform’s labor force. Stylized facts on the profitability of the top ten global labor platforms and a descriptive analysis of their cost structures are presented. We further argue that the modes of production and competition inherent in digital labor platforms are critical to this profitability puzzle because they determine the upper limit of surplus value extraction in production and the heavy financial burden of profit generation for labor platforms. JEL Classification: P12, E24, D40
Inhibitory Activities of Extracts from Chinese Medicinal Herbs on α-Amylase, α-Glucosidase,and Pancreatic Lipase
Authors: Liu Xiang , Nie Yuhao , Chen Rui , Zhang Xiaoying , Yue Lijuan , Chen Chen 
Published: July 2023

Background Metabolic syndrome is an assortment of conditions that often happens together and upsurge your risk of diabetes, stroke, and heart disease. One strategy for the prophylaxis and treatment of diabetes and obesity is to inhibit the enzymes activities, which include α-glucosidase, α-amylase, and pancreatic lipase. Objectives To screen the effect of 16 Chinese medicinal herbs on inhibition of α-glucosidase, α-amylase, and pancreatic lipase. Materials and Methods The water extraction of 16 traditional Chinese herbal medicines was used to estimate activity in vitro from different families against α-glucosidase, α-amylase, and pancreatic lipase by using spectrophotometry with p-nitrophenyl-α-D-glucopyranoside (PNPG), starch derivatives, and 4-methylumbelliferone (4-MUO), respectively, as a substrate. Results The results showed that the water extraction yield of the 16 rhizomes ranged from 0.2% to 4.0%. Among the tested extracts, the extract from Gastrodia elata exhibited the strongest effect on α-amylase (The half-maximal inhibitory concentration (IC50)) = 4.10 mg/mL). The extracts from Pinellia ternate and Arisaema heterophyllum exhibited noteworthy effects on α-glucosidase (IC50 = 29.21 and 41.13 µg/mL, respectively), and Corydalis turtschaninovii possessed the highest effect on pancreatic lipase (IC50 = 4.11 µg/mL) and a stronger effect than orlistat (IC50 = 4.52 µg/mL). Conclusion This study provides a basis for screenings and in-depth studies of anti-obesity and anti-diabetes drugs. Further isolation, identification, and characterization of active compounds should be carried out in the future.
Imatinib mesylate-induced acute hepatotoxicity
Authors: Frikha Imen , Fakhfakh Yousra , Sahnoun Rim , Chtourou Lassaad , Medhaffar Moez , Elloumi Moez 
Published: July 2023

Introduction Imatinib is a first-line selective tyrosine kinase inhibitor used for the treatment of chronic myeloid leukemia. Although imatinib-induced hepatotoxicity may aggravate the patient's clinical condition and alter the treatment plan, the mechanism of imatinib-induced hepatotoxicity has rarely been investigated. Case report We report a 51-year-old man, suffering from acute toxic hepatitis after 5 months of imatinib treatment for chronic myeloid leukemia. Management and outcome The outcome was favorable after discontinuation of treatment with normalization of biological liver function after 12 weeks. The treatment was switched to nilotinib without any incidents. Discussion Regular liver function test monitoring is recommended during imatinib treatment. In fact of acute hepatic toxicity, treatment with imatinib should be stopped in the case of cytolysis more than five times the upper limit of normal.
Onset of Inattention and Hyperactivity in Children and Adolescents With Epilepsy 6 months After the Diagnosis
Authors: Rogač Željka , Stevanović Dejan , Bečanović Sara , Dimitrijević Aleksandar , Andrić Ivana , Božić Ljubica , Nikolić Dimitrije M. 
Published: July 2023

Objective: Complete or major symptoms of ADHD are often present in epilepsy. This study evaluated inattention and hyperactivity symptoms over the first 6 months in newly diagnosed pediatric epilepsy without comorbid ADHD. Method: Children and adolescents with newly diagnosed epilepsy were followed for 6 months after starting antiseizure medications. The Nisonger Child Behavior Rating Form (NCBRF), Adverse Event Profile (AEP), and the Revised Wechsler Intelligence Scale for Children were used. Results: There was a marked increase in attention difficulties while a moderate increase in hyperactivity levels. AEP scores, changes in non-verbal aspects of intelligence, levels of hyperactivity at the follow-up, and attention at baseline were significant predictors for inattention. In contrast, only levels of hyperactivity at the baseline and inattention at the follow-up were significant predictors for hyperactivity. Conclusion: Significant inattention and hyperactivity levels originated 6 months after the diagnosis of epilepsy and starting antiseizure medication.
Retinal microvascular changes in unilateral functional amblyopia detected by oct-angiography and follow-up during treatment
Authors: Errera Charlotte , Romann Julia , Solecki Lauriana , Gaucher David , Ballonzoli Laurent , Bourcier Tristan , Sauer Arnaud 
Published: July 2023

Objective To evaluate the macular microvascular changes using optical coherence tomographic angiography (OCT-A) in children with unilateral amblyopia and their reversibility during treatment. Methods Patients with unilateral strabismic or anisometropic amblyopia or residual amblyopia from early congenital cataract surgery, examined between October 2019 and March 2021, were included. Vessel density and perfusion density in the superficial capillary plexus and area, perimeter and circularity of the foveal avascular zone (FAZ) were analysed using OCT-A in amblyopic eyes, contralateral eyes and control group healthy eyes. Correlation analyses between the microvascular parameters and the visual acuity were performed. In a pilot study on a few patients from the amblyopic cohort, longitudinal follow-up during treatment was also performed. Results A total of 128 eyes of 64 patients were included: 32 amblyopic eyes compared with 32 contralateral eyes and 64 control eyes. Vessel density and perfusion density in the superficial capillary plexus were significantly lower in amblyopic eyes compared to control eyes in 6 × 6 mm ( p < 0.02) and 3 × 3 mm ( p < 0.01) scans. Correlation analyses showed a linear decrease in vessel density and perfusion density with decreasing visual acuity. The microvascular changes observed were reversible with the occlusion treatment of amblyopia ( p < 0.001). Conclusions The study found a decrease in vessel density and perfusion density in the macula of children with unilateral functional amblyopia. These microvascular changes were correlated with visual acuity and appeared to be reversible with treatment of amblyopia. On the whole, OCT-A appears to be a relevant complementary examination when it comes to diagnosing and monitoring functional amblyopia.
Clinical characteristics of hemodialysis patients with left brachiocephalic vein obstruction due to extrinsic compression or prior catheterization
Authors: Wan Ziming , Lai Qiquan , Zhou Yu , Chen Ling , Gao Xuejing , Tu Bo , Chen Bo 
Published: July 2023

Background: Left brachiocephalic vein (LBCV) stenosis is a common complication in hemodialysis patients and is a heterogenous disorder associated with either prior catheterization or extrinsic compression. This study aimed to characterize patients with LBCV stenosis or occlusion with and without a history of central venous catheterization. Methods: We performed a retrospective study in 84 hemodialysis patients with LBCV stenosis or occlusion with ( n = 22) or without ( n = 62) prior catheterization. We compared the clinical features, anatomical factors, restenosis after balloon venoplasty, and patency rates of patients in these two groups. Results: In the cohort of 84 patients with LBCV stenosis or occlusion, 73.8% (62 patients) of them had no history of catheterization. Patients without prior catheterization had more stenotic lesions ( p < 0.05) but less occlusive lesions ( p < 0.05) than patients with prior catheterization. The space between the sternum and the aorta was narrower in patients without prior catheterization than that in patients with prior catheterization ( p < 0.05). Percutaneous venography was performed in 81 patients, and the occurrence of recoil after venoplasty in patients without prior catheterization was significantly higher than that in patients with prior catheterization ( p < 0.05). The rate of stent implantation was significantly higher in patients without prior catheterization than patients with prior catheterization ( p < 0.05), whereas there was no significant difference in primary patency between the two groups. Conclusions: LBCV stenosis and occlusion are mainly due to extrinsic compression rather than prior central venous catheterization. Stent implantation is frequently required after venoplasty to treat LBCV obstructive lesions in patients without prior catheterization.
Assessing the educational value and content of YouTube videos for ultrasound-guided subclavian vein catheterization
Authors: Satilmis Tulin , Basaran Betul 
Published: July 2023

Background: The European Society of Anaesthesiology (ESA) published a guideline regarding continuous ultrasound guidance for central venous catheters in 2020. YouTube has been a popular educational platform since its inception. The purpose of the present study was to evaluate the adequacy of videos on ultrasound-guided subclavian vein catheterization posted on YouTube based on this guideline. Method: YouTube was scanned using the keywords associated with ultrasound-guided subclavian vein catheterization and 46 of the 106 most-watched videos were included in the study. The videos were divided into three groups, as individual, manufacturer, and academic according to their sources, and were evaluated as poor, satisfactory, and good in terms of the overall content. The videos were then evaluated based on ESA’s six-title guide for more specific informational content. Results: A total of 46 videos were reviewed and 52.2% ( n = 24) were found to be prepared by individuals. Among the videos, the rate of videos describing only venipuncture (poor) was 23.9% ( n = 11), 73.9% ( n = 34) of videos described the verification of the guidewire location with venipuncture, and 2.2% of videos described all the recommendations suggested by the guide ( n = 1). At the end of the catheterization procedure, 4.3% ( n = 2) stated that the catheter location should be confirmed by using ultrasound, 15.2% ( n = 7) recommended chest-X-ray, and 80.4% ( n = 37) did not suggest any. Conclusion: Manufacturer and academic videos can be watched due to their high-quality scores, but it may be practical to prepare training videos with guidelines both for educators and students to have global access to the renewed guideline information.
Patient-reported outcomes and prognostic factors in ankle fracture-dislocation: A systematic review
Authors: Ahmed Ramsha , Ward Alex E , Thornhill Elizabeth 
Published: July 2023

Objectives Ankle fractures have an incidence of around 90,000 per year in the United Kingdom. They affect younger patients following high energy trauma and, in the elderly, following low energy falls. Younger patients with pre-existing comorbidities including raised BMI or poor bone quality are also at risk of these injuries which impact the bony architecture of the joint and the soft tissues leading to a highly unstable fracture pattern, resulting in dislocation. At present, there is no literature exploring what effect ankle fracture-dislocations have on patients’ quality of life and activities of daily living, with only ankle fractures being explored. Methods Relevant question formatting was utilised to generate a focused search. This was limited to studies specifically mentioning ankle injuries with a focus on ankle fracture-dislocations. The number of patients, fracture-dislocation type, length of follow up, prognostic factors, complications and outcome measures were recorded. Results Nine hundred and thirty-nine fractures were included within the studies. Eight studies looked at previously validated foot and ankle scores, two primarily focused on the American Orthopaedic Foot and Ankle Society score (AOFAS), three on the foot and ankle outcome score (FAOS), and one study on the Olerud–Molander score (OMAS). Patient, injury, and management factors were identified as being associated with poorer clinical outcomes. Conclusions Not only are age and BMI a risk factor for posttraumatic osteoarthritis but they were also identified as prognostic indicators for functional outcome in this review. Patients sustaining a concurrent fracture-dislocation were found to have poorer clinical outcomes, and the timing and success of reduction further influenced outcomes. This review found that the quality of reduction was directly related to the patients’ functional outcomes post-follow up, and the risk of developing posttraumatic osteoarthritis, which was more frequent in patients sustaining Bosworth fractures, posterior malleolar fractures, and in patients with increasing age. Level of evidence IV.
A Randomized Clinical Trial to Evaluate a Digital Therapeutic to Enhance Gait Function in Individuals With Parkinson’s Disease
Authors: Alberts Jay L. , Kaya Ryan D. , Penko Amanda L. , Streicher Matthew , Zimmerman Eric M. , Davidson Sara , Walter Benjamin L. , Rosenfeldt Anson B. 
Published: July 2023

Background Postural instability and gait dysfunction (PIGD) is a cardinal symptom of Parkinson’s disease (PD) and is exacerbated under dual-task conditions. Dual-task training (DTT), enhances gait performance, however it is time and cost intensive. Digitizing DTT via the Dual-task Augmented Reality Treatment (DART) platform can expand the availability of an effective intervention to address PIGD. Objective The aim of this project was to evaluate DART in the treatment of PIGD in people with PD compared to a Traditional DTT intervention. It was hypothesized that both groups would exhibit significant improvements in gait, and the improvements for the DART group would be non-inferior to Traditional DTT. Methods A single-blind randomized controlled trial was conducted with 47 PD participants with PIGD. Both groups completed 16 therapeutic sessions over 8 weeks; the DART platform delivered DTT via the Microsoft HoloLens2. Primary outcomes included clinical ratings and single- and dual-task gait biomechanical outcomes. Results Clinical measures of PD symptoms remained stable for DART and Traditional DTT groups. However, both groups exhibited a significant increase in gait velocity, cadence, and step length during single- and multiple dual-task conditions following the interventions. Improvements in gait velocity in the DART group were non-inferior to Traditional DTT under the majority of conditions. Conclusion Non-inferior improvements in gait parameters across groups provides evidence of the DART platform being an effective digital therapeutic capable of improving PIGD. Effective digital delivery of DTT has the potential to increase use and accessibility to a promising, yet underutilized and difficult to administer, intervention for PIGD. Clinical Trial Registration ClinicalTrials.gov Dual-task Augmented Reality Treatment for Parkinson’s Disease (DART) NCT04634331; posted November 18, 2020.
A machine learning analysis of patient and imaging factors associated with achieving clinically substantial outcome improvements following total shoulder arthroplasty: Implications for selecting anatomic or reverse prostheses
Authors: Kunze Kyle N , Bobko Aimee , Mathew Joshua I , Polce Evan M , Manzi Joseph E , Nicholson Allen , Finocchiaro Anthony , Estrada Jennifer , Zeitlin Jacob , Meza Blake , Taylor Samuel , Blaine Theodore A , Warren Russell F , Fu Michael C , Dines Joshua S , Gulotta Lawrence V 
Published: July 2023

Background Indications for reverse total shoulder arthroplasty(rTSA) continue to expand making it challenging to predict whether patients will benefit more from anatomic TSA(aTSA) or rTSA. The purpose of this study was to determine which factors differ between aTSA and rTSA patients that achieve meaningful outcomes and may influence surgical indication. Methods Random Forest dimensionality reduction was applied to reduce 23 features into a model optimizing substantial clinical benefit (SCB) prediction of the American Shoulder and Elbow Surgeon score using 1117 consecutive patients with 2-year follow up. Features were compared between aTSA patients stratified by SCB achievement and subsequently with rTSA SCB achievers. Results Eight combined features optimized prediction (accuracy = 87.1%, kappa = 0.73): (1) age, (2) body mass index (BMI), (3) sex, (4) history of rheumatic disease, (5) humeral head subluxation (HH) on computed tomography (CT), (6) HH–acromion distance on X-ray, (7) glenoid retroversion on CT, and (8) Walch classification on CT. A higher proportion of males (65.6% vs. 54.9%, p = 0.022), Walch B-C glenoid morphologies (49.5% vs. 37.9%, p < 0.001), and greater BMI (30.1 vs. 26.5 kg/m2, p = 0.038) were observed in aTSA nonachievers compared with aTSA achievers, while aTSA nonachievers were statistically similar to rTSA achievers. Discussion Patients with glenohumeral osteoarthritis and intact rotator cuffs that have a BMI > 30 kg/m2 and exhibit Walch B-C glenoids may be less likely to achieve the SCB following aTSA and should be considered for rTSA.