bluuebunny/crossref_metadata_2025_split huggingface dataset:
Urban Datarization for unalienating urban design and built environment in Society 5.0
Authors: Shanti L , Sihombing A , Fuad A H 
Published: May 2023

Abstract
Discourse on alienation has been widely discussed from a social and psychological point of view. The influence of the physical environment in the urban context has not been widely discussed, although the physical environment often affects the behaviour and psychological state of humans around it. This article is structured to describe the extent of alienation discourse in the urban built environment so that the discussion on this topic can be deepened in the context of society 5.0 where urban life’s quality can be improved with the use of data. This article was compiled using the literature review method by collecting discussions related to this topic that had been produced previously, then structuring and mapping it. The conclusion is that there are aspects of the urban built environment that contributes to urban alienation. These aspects can be defined in a more empirical data so that continues monitoring can be done to improve the quality or urban built environment that heads towards no alienation for its citizens, especially to its workers.
Industrial Symbiosis in Green Industrial Estate: Potential and Problems
Authors: Noegroho N , Wijaksono S 
Published: May 2023

Abstract
Industrial Symbiosis (IS) can give multiple benefits not only to the environment but also to the economic and social aspects. From an environmental point of view, this IS supports the implementation more ‘green’ environment in Industrial Estate. However, there are some problems with IS implementation. The objective of this paper is to investigate the potential and problems associated with IS implementation in Industrial Estate, especially in Indonesia. The method used in this research is a case study by analysing the existing area and interviewing stakeholders. The result of the analysis shows that differences in time development of each industry and the use of technology to link industries can affect the optimization of industrial symbiosis in the Industrial Estate.
The Use of Local Wind Simulation in Healthcare Facilities for Disease Control
Authors: Djimantoro M I , Tumiwa A E 
Published: May 2023

Abstract
Ventilation and air circulation are essential elements in healthcare facilities. Moreover, good ventilation helps to dilute odour pollutants and control the spread of the disease. This air circulation generally uses mechanical ventilation, whereas the use of natural ventilation is encouraged by the Indonesian Ministry of Health and the World Health Organization due to its affordability and sustainability considerations. Therefore, this paper aims to study the optimal building composition for health facilities using natural ventilation. There are two parts of the discussion in this manuscript. The first part is to study the building shape based on local wind characteristics. The second part is to determine the layout of the interior, adapting to the prevailing wind and its function. The research approach uses venturi theory, solar atrium and cross-ventilation, which is simulated through several computer simulations. The result showed that by orchestrating the building composition and layout in a specific way, natural ventilation could remove disease particles and provide better air circulation. These findings can be a new discussion in the planning and design of health facilities due to natural ventilation.
Eco-tourism through carrying capacity in Eris Village North Sulawesi: problems in process
Authors: Noegroho N , Ardiani YM , Agustina IA 
Published: May 2023

Abstract
A tourist destination must be developed in a balanced way, making the destination attractive to tourists while maintaining the sustainability of its environment. Destinations are developed not only to provide comfort for tourists by build various facilities but also to provide comfort for local people living in the place. One of the efforts is to develop eco-friendly tourist destinations including the facilities built in it. If development is carried out by destroying the environment, many parties will be harmed, as a result, tourists are not interested to visit. Therefore, create a sustainable tourist destination is important based on its carrying capacity. The advantages are knowing the threshold so that the destination does not over tourism and the environment itself is still maintained and remains comfortable for tourists and the local community. This research was conducted to develop sustainable tourist destinations, but focus only on the measurement process. The goal is to find out the problems that occur in the process so that it can be an anticipatory step in the process of developing a sustainable tourist destination. The method used in this research is a case study in Eris Village in North Sulawesi, where this village has natural and community conditions that have the potential to be developed as a tourist destination. Interviews were conducted with stakeholders to find out their development projections. The results obtained show that the determination of destination spots at the beginning of the process becomes an important issue in creating sustainable tourist destination especially its carrying capacity.
Thermal expansion flow analysis in designing a sustainability computer personal unit casing
Authors: Sahroni T R , Ahmad S A , Akmal S 
Published: May 2023

Abstract
The material of computer personal unit is commonly used metal based. The problem occurs when waste of electronic device to be recycled. This paper describes the thermal expansion flow in designing a sustainability computer personal unit (CPU) casing based on the material selection technique. In this study, the design concepts were generated to be processed for screening matrix with criteria selection of comfortable, user friendly, ergonomic, flexible, functionality and material. Design concept 4 was selected to be further analyzed. The material selection technique was used in this study using CES Edupack and provide the material of Acrylonitrile butadiene styrene (ABS), Polyetheretherketone (PEEK), and Polyoxymethylene (Acetal, POM) for analysis based on criteria of recycle ability, price, hardness, density, and temperature maximum. The ABS material suits the design requirement toward sustainability computer personal unit. Based on the simulation result, the thermal expansion flow meets the design specification. In addition, the phenomena of heat dissipated from internal CPU shows significant information for design manufacturing to manage and place the electronic parts properly to reduce the risk of overheated and damaged.
Cookies Product Development with the Addition of Turmeric Extract
Authors: Renzo A , Tedjakusuma F , Surya R 
Published: May 2023

Abstract
Turmeric (Curcuma longa L.) was used to develop novel formulated cookies, which have rich traditional culinary values. Turmeric extract (0.5 and 1%) were used as an added ingredient in cookies (with 0% as a control or those cookies without extracts). Results showed that antioxidant activity increase along addition of turmeric and lower temperature. This can be related to the baking process damaging heat-sensitive antioxidants. Proximate analysis showed that the addition of 1% turmeric extract increased the protein and ash content. Protein content in turmeric cookies even higher to SNI. Further, results of sensory evaluation revealed cookies with 1% turmeric extract and baking temperature of 180°C for 20 min was the most preferred formulation by the panellists. The panellists gave a higher preference for cookies that have a crunchy-hard texture and bright yellow colour.
Physicochemical Properties of Enzymatically Modified Starch: A Review
Authors: Hutabarat Donald John Calvien , Stevensen Jansen 
Published: May 2023

Abstract
Common enzymes used in starch modification include α-amylase, β-amylase, glucoamylase, isoamylase, and pullulanase. Botanical sources of starch are widely used in grains, beans, and tubers. The modification of starch is used to change the lack of native starch properties and make the desired physicochemical properties. Besides, starch modification can produce resistant starch (RS), which is essential for health concerns. The review aims to provide information on the enzymatic modification of starch and its effect on changes in the physicochemical properties of various botanical starch sources. Changes in physicochemical properties in modified starch include granular morphology, crystalline type, paste properties, swelling power, and solubility.
The stability of total phenolic and antioxidant activity during processing and cooking of sorghum-moringa substituted tapioca noodle
Authors: Sadek NF , Hamidah RS 
Published: May 2023

AbstractAdding sorghum (Sorghum bicolorL. Moench) dan moringa (Moringa oleifera) leaf powder into tapioca noodle formulation was expected to improve health functional properties. This study evaluated the total phenolic content (TPC) and antioxidant activity in each step of noodle processing (including mixing, steaming, sheeting-slitting, and oven drying) and boiling. Noodle formulation was tapioca and sorghum flours (80:20) with a 5% moringa leaf powder addition. The TPC and antioxidant activity were analyzed using Folin Ciocalteu and DPPH (2,2-diphenyl-1-picrylhydrazyl) assays. The concentration of DPPH solution used in this study was 0.1 M. The TPC and antioxidant stability was significantly affected during processing and boiling. The TPC retention was highest in sample taken from sheeting-slitting step (0,27±0,001 mg GAE/g), while the antioxidant activity was found to be highest in the samples taken from oven drying (90.29±0.158 %). This result indicated that the heat involved expressed positive influences, except for the boiling effect in TPC. Heat treatment was proposed to release antioxidant compounds from food matrices, but the presence of water as a boiling medium may lead to phenolic leaching. Other bioactive compounds might also play a role in antioxidant activity due to a very weak correlation between TPC and antioxidant activity. High ability in DPPH reduction made the noodle could be proposed as a potential source of antioxidants.
The nutritional content, omega fatty acids, and amino acids profiles of sorghum-moringa substituted tapioca noodles
Authors: Sadek N F , Hamidah R S , Murwani I A 
Published: May 2023

Abstract
Sorghum (Sorghum bicolor L. Moench) and moringa (Moringa oleifera) could be utilized to develop an innovative and functional food product, especially for stunting prevention, due to their nutritional content. In this study, those commodities were incorporated into tapioca noodle formulation, with the ratio of sorghum and tapioca flours was 20:80 and 5% moringa leaf flour. This formula resulted in 4.12% protein, 1.15% fat, 81.75% carbohydrate, and 5.88% dietary fiber and provided 353.77 kcal energy per 100g product. This made our product could be considered low-fat and a source of dietary fiber. Magnesium (42.89 mg/ 100 g), phosphorus (68.18 mg/100 g), zinc (0.58 mg/100 g), and iron (4.21 mg/100 g) were minerals presented in the product, while no vitamin A and D were detected. The complete essential amino acids were also found in this product, with 5.5; 26.4; and 32.7 mg/100 g of omega-3, -6, and -9 fatty acids, respectively. This result indicated the potency of health-promoting effects in stunted children. However, future research should emphasize increasing the protein content of sorghum-moringa substituted tapioca noodles.
The effect of potato starch and xanthan gum addition on cilantro sauce product development
Authors: Inneke Gracia , Kristopo Hari 
Published: May 2023

AbstractThis study aims to identify consumers’ most liked formulation and evaluate the effect of thickening agents of potato starch (PS) and xanthan gum (XG) on the overall acceptability of cilantro sauces, viscosity, and pH. There are five formulas to be tested: F1 (1% PS), F2 (0.75% PS: 0.25% XG), F3 (0.50% PS: 0.50% XG), F4 (1% XG), and F5 (control). The results show significant differences based on taste and texture in the acceptance test, but no significant differences were discovered based on color and aroma. While no significant changes were identified in pH, there was a substantial difference in the viscosity test for each formulation. Based on the results, the ideal formulation for cilantro sauce consists of 0.75% PS and 0.25% XG (F2).
Texture and mechanical properties of quenching and partitioning steel
Authors: Hu Pengsheng , Su Yu , Li Jun , Zuo Zhicheng 
Published: May 2023

Abstract
Advanced high-strength steels, such as quenching and partitioning (Q&P) steels, are of considerable interest in the automotive industry owing to their desirable mechanical properties. However, further research is required to elucidate the relationship between the microstructure and mechanical properties of Q&P steels. Therefore, this study investigated the microstructure, texture, and mechanical properties of Fe0.23C1.55Si1.92Mn0.04Al Q&P steel prepared under different conditions. After tensile deformation, the intensity of the H {001}〈110〉 orientation in the samples increased from 2.47 to 3.51. The sample partitioned at 375 °C for 60 s had the highest ultimate tensile strength of 1446 MPa. The sample partitioned at 450 °C for 180 s achieved the highest elongation at fracture of 17.7%. As the partitioning temperature (PT) increased, the width of the lath martensite increased, the volume fraction of primary martensite decreased, and the secondary martensite of the III sample increased. As the partitioning time (Pt) increased, the size and content of secondary martensite decreased.
A global assessment of national road network vulnerability
Authors: Koks Elco , Rozenberg Julie , Tariverdi Mersedeh , Dickens Ben , Fox Charles , van Ginkel Kees , Hallegatte Stephane 
Published: May 2023

Abstract
Every country relies on a well-functioning road system. However, we do not have a clear understanding yet of the vulnerability of each of these road networks to different forms of disruption. In this study, we aim to better understand how road networks are affected by different disruptive events, to identify hotspots of road network vulnerabilities, and to better target where and what type of future investments can be made to develop more resilient networks. To do so, we developed a fully open-source modelling framework to expose over 200 country road systems across the world to random, local, and targeted disruption schemes. For each country, we assessed the impact of such disruptions on intra-country travel activities and regional accessibility. The results highlight the vulnerability of road systems in mountainous and small-island countries owing to the limited availability of alternative routes. Additionally, we find that, on average, low-income countries experience a collapse of road-system services with much fewer disruptions, relative to high-income countries, due to the lack of redundancy in their systems. While the value of goods and services disrupted may be higher in wealthier countries, the results highlight that from an equity perspective, transport infrastructure investments are more desired in low-income country networks.
Reconsidering frailty from a human and social sciences standpoint: towards an interdisciplinary approach to vulnerability
Authors: Sabot Philippe , Di Martino Carla , Moroni Christine , Pentini Anna Aluffi , Pabjan Barbara , Machado Maria Manuela Pereira , Katkonienė Agata , Czajkowski Paweł , Bardauskienė Raminta , Beuscart Jean-Baptiste ,   Coverage Collaborative Group, Encarnação Paula , Fernandes Anabela Silva , Fabio Olivieri , Fernandez Diego Pinal , Pivoriene Jolanta , Posłuszny Łukasz , Petronilho Fernando Alberto Soares , Sourial Nadia , Sousa Sonia S , Teodorescu Adriana , Vedel Isabelle , Zemaitaityte Irena , Zuber Marcelina 
Published: May 2023

Abstract
Although frailty is an important, well-characterized concept in the provision of medical care to older adults, it has not been linked to the concept of vulnerability developed in the humanities and social sciences. Here, we distinguish between the two main dimensions of vulnerability: a fundamental, anthropological dimension in which people are exposed to a risk of injury, and a relational dimension in which people depend on each other and on their environment. The relational notion of vulnerability might provide healthcare professionals with a better understanding of frailty (and its potential interaction with precarity). Precarity situates people in their relationship with a social environment that might threaten their living conditions. Frailty corresponds to individual-level changes in adaptation to a living environment and the loss of ability to evolve or react in that environment. Therefore, we suggest that by considering the geriatric notion of frailty as a particular form of relational vulnerability, healthcare professionals could better understand the specific needs of frail, older people—and thus provide more appropriate care.
Changes in Personal Protective Equipment Usage Among Healthcare Personnel From the Beginning of Pandemic to Intra-COVID-19 Pandemic in Thailand
Authors: Mahasing Chayanit , Kittikraisak Wanitchaya , Mott Joshua A , Yoocharoen Pornsak , Piyaraj Phunlerd , Tanathitikorn Chuleekorn , Punjasamanvong Somsak , Wongrapee Thanapat , Suttha Patama , Rattanathumsakul Thanit , Davis William W , Westercamp Matthew , Chottanapund Suthat 
Published: May 2023

Abstract

Objectives
Personal protective equipment (PPE) use is associated with reduced risk of SARS-CoV-2 infection among healthcare personnel (HCP). There are limited data on the impact of the novel coronavirus disease 2019 (COVID-19) pandemic on the PPE use of HCP. We describe the changes in PPE use from just before the widespread of community outbreaks (‘pre-pandemic’) to intra-pandemic time points, and examine factors associated with not changing in PPE use behavior among HCP in four Thai hospitals.

Methods
We performed a retrospective cohort evaluation using two-time points: (i) February-March 2020 (pre-pandemic period); and (ii) January–March 2021 (intra-pandemic period). Self-reported frequency of appropriate PPE use was measured by a Likert scale. We used multivariable logistic regression to identify factors associated with no increase in self-reported PPE use.

Results
Of 343 HCP, the proportion of participants reporting ‘always’ using PPE rose from 66% during the pre-pandemic period to 80% during the pandemic. Factors associated with HCP who did not increase in PPE use included having high baseline reported PPE, being a non-registered HCP (e.g. nurse assistants, dental assistants, porters), being male, and having a low perceived risk of becoming infected with any respiratory virus while working in the hospital.

Conclusion
PPE education, training, and risk communication content should target all cadres of HCP, regardless of registered/non-registered status, with a focus on behavior change for improved prevention and control of SARS-CoV-2 and other respiratory viruses in healthcare settings.
KGANSynergy: knowledge graph attention network for drug synergy prediction
Authors: Zhang Ge , Gao Zhijie , Yan Chaokun , Wang Jianlin , Liang Wenjuan , Luo Junwei , Luo Huimin 
Published: May 2023

Abstract
Combination therapy is widely used to treat complex diseases, particularly in patients who respond poorly to monotherapy. For example, compared with the use of a single drug, drug combinations can reduce drug resistance and improve the efficacy of cancer treatment. Thus, it is vital for researchers and society to help develop effective combination therapies through clinical trials. However, high-throughput synergistic drug combination screening remains challenging and expensive in the large combinational space, where an array of compounds are used. To solve this problem, various computational approaches have been proposed to effectively identify drug combinations by utilizing drug-related biomedical information. In this study, considering the implications of various types of neighbor information of drug entities, we propose a novel end-to-end Knowledge Graph Attention Network to predict drug synergy (KGANSynergy), which utilizes neighbor information of known drugs/cell lines effectively. KGANSynergy uses knowledge graph (KG) hierarchical propagation to find multi-source neighbor nodes for drugs and cell lines. The knowledge graph attention network is designed to distinguish the importance of neighbors in a KG through a multi-attention mechanism and then aggregate the entity’s neighbor node information to enrich the entity. Finally, the learned drug and cell line embeddings can be utilized to predict the synergy of drug combinations. Experiments demonstrated that our method outperformed several other competing methods, indicating that our method is effective in identifying drug combinations.
BUSZ: compressed BUS files
Authors: Einarsson Pétur Helgi , Melsted Páll 
Published: May 2023

Abstract

Summary
We describe a compression scheme for BUS files and an implementation of the algorithm in the BUStools software. Our compression algorithm yields smaller file sizes than gzip, at significantly faster compression and decompression speeds. We evaluated our algorithm on 533 BUS files from scRNA-seq experiments with a total size of 1TB. Our compression is 2.2× faster than the fastest gzip option 35% slower than the fastest zstd option and results in 1.5× smaller files than both methods. This amounts to an 8.3× reduction in the file size, resulting in a compressed size of 122GB for the dataset.

Availability and implementation
A complete description of the format is available at https://github.com/BUStools/BUSZ-format and an implementation at https://github.com/BUStools/bustools. The code to reproduce the results of this article is available at https://github.com/pmelsted/BUSZ_paper.