bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the role of value chain formation in the scaling of crop diversification
Authors: Weituschat Chiara Sophia , Pascucci Stefano , Materia Valentina Cristiana , Blasi Emanuele 
Published: February 2023

AbstractSignificant detrimental effects of agricultural intensification and specialization are becoming increasingly evident. Reliance on monocultures, few varieties, and intensive use of agrochemicals is a major factor in climate change, biodiversity decline, soil health deterioration, and pollution, putting our food system at risk. This requires sustainable agricultural processes, such as crop diversification, to be more rapidly and effectively tested, adopted, and scaled. While these processes are typically introduced at niche level, they often struggle to scale and to induce broader sustainability transitions. In this study, we investigate how scaling may occur, focusing on institutional logics, their changes, and realignment over time. In particular, we applied an abductive research strategy to collect empirical evidence from two in-depth, longitudinal case studies of innovation niches related to crop diversification. Doing so, we show for the first time that, despite their many differences, scaling processes of crop diversification in both niches converge, presenting similar progressions in terms of institutional dimensions, and facing similar obstacles when it comes to value chain formation. While initial experimentation could still be implemented using organizational forms familiar to the lead actors, we discover that a systemic lack of adequate value chain arrangements obstructed the scaling process of crop diversification in both cases. These findings have been used to reflect on the role of value chain relations in scaling processes in sustainability transitions in agriculture.
Cystectomie en urinedeviatie bij interstitiële blaasafwijkingen
Authors: Nieuwenhuijzen Jakko A. , van der Sluis Tim M. 
Published: February 2023

SamenvattingDoel van de studie was evaluatie van de beschikbare literatuur over de kans op succes van urinedeviaties al dan niet met cystectomie bij patiënten met bekkenpijnsyndroom / interstitiële cystitis. Er werden drie reviews gevonden en nul gerandomiseerde trials. In de 21 geselecteerde case series werden in totaal 475 patiënten geïncludeerd. De kans op succes van een urinedeviatie was 81%. Voorspellers voor de kans op succes (aanwezigheid van een Hunnerse laesie en kleine blaascapaciteit) konden niet worden bevestigd vanwege de heterogeniteit van de studies. Urinedeviatie in combinatie met verwijdering van de blaas was na cystectomie succesvol in 96% van de gevallen, na partiële cystectomie in 75% en na urinedeviatie en zonder cystectomie in 79% van de gevallen. Concluderend kan worden gesteld dat harde wetenschappelijke onderbouwing voor of tegen een urinedeviatie bij bekkenpijnsyndroom / interstitiële cystitis ontbreekt, omdat de (best goede) resultaten in de case series alleen kunnen worden geïnterpreteerd met inachtneming van (inclusie)bias. Op grond hiervan moeten therapiekeuzes nog steeds op individuele basis worden gemaakt.
Themapoli voor ketamine-geïnduceerde cystitis: eerste ervaringen en resultaten
Authors: van der Sanden Wouter M. H. , Wyndaele Michel , Schipper Robert A. , de Kort Laetitia M. O. 
Published: February 2023

SamenvattingRecreatief ketaminegebruik neemt toe in Nederland. Ketaminemisbruik kan leiden tot schade aan de urinewegen, waardoor urogenitale klachten ontstaan met forse impact op de kwaliteit van leven. Dit artikel gaat over de eerste Nederlandse themapoli met diagnose- en behandelprotocol voor patiënten met ketamine-geïnduceerde urogenitale klachten. Tot op heden zagen we 30 patiënten, van wie 10% betrokkenheid had van de hoge urinewegen. Aanvullende diagnostiek en behandeling waren gefocust op preservatie van nierfunctie. De overige 90% werd gecounseld met als doel te stoppen met ketaminegebruik. Urogenitale klachten werden medicamenteus behandeld. 71% van deze patiënten slaagde erin binnen drie maanden te stoppen met ketaminegebruik en had significant (p < 0,05) vaker afname van klachten dan de groep die niet stopte. Het is belangrijk ketaminemisbruik te erkennen als mogelijke oorzaak van urogenitale klachten bij jonge patiënten, enerzijds vanwege het gevaar voor de hoge urinewegen en anderzijds omdat urogenitale klachten een impactvolle groep aandoeningen is die reversibel is bij stoppen met ketamine.
Oxygen transfer and hydrodynamic evaluation in a multistage flexible fibre biofilm reactor
Authors: Abdulgader M. , Yu Q. J. , Zinatizadeh A. A. , Williams P. , Rahimi Z. 
Published: February 2023

AbstractIn present work, the hydrodynamic studies and determination of oxygen mass transfer coefficients (KLa) were conducted in a multistage flexible fibre biofilm reactor developed for treating milk processing wastewater. In this regard, the residence time distributions in the MS-FFBR under various operating conditions as water flow rates, airflow rates, and hydraulic retention times were analysed using tracer experiments. The results revealed that the reactor’s hydraulic regime is similar to a continuous stirred tank reactor. Furthermore, the multistage flexible fibre biofilm reactor exhibited a lower oxygen mass transfer coefficient (KLa of 11.955 1/h at AFR/WFR of 47) than that reported for continuous stirred tank reactor in the literature at similar WFRs and AFRs (KLa of 15 1/h at AFR/WFR of 40). From the results, dissolved oxygen transfer was hindered to some extent owing to the presence of the fibre packing.
Adrenal insufficiency in thyroid cancer patients treated with tyrosine kinase inhibitors and detected by ACTH stimulation test
Authors: Valerio L. , Giani C. , Matrone A. , Pontillo-Contillo B. , Minaldi E. , Agate L. , Molinaro E. , Elisei R. 
Published: February 2023

Abstract
Purpose
Advanced thyroid cancer patients treated with tyrosine kinase inhibitors (TKI) can develop several adverse events (AEs), including adrenal insufficiency (AI).

Methods
We studied 55 patients treated with TKI for radioiodine-refractory or medullary thyroid cancer. The adrenal function was evaluated during follow-up by performing serum basal ACTH, and basal and ACTH-stimulated cortisol.

Results
Twenty-nine/55 (52.7%) patients developed subclinical AI during TKI treatment as demonstrated by a blunted cortisol response to ACTH stimulation. All cases showed normal values of serum sodium, potassium and blood pressure. All patients were immediately treated, and none showed an overt AI. Cases with AI were all negative for adrenal antibodies and did not show any adrenal gland alteration. Other causes of AI were excluded. The onset time of the AI, as measured in the subgroup with a first negative ACTH test, was < 12 months in 5/9 (55.6%), between 12 and 36 months in 2/9 (22.2%) and > 36 months in 2/9 (22.2%) cases. In our series, the only prognostic factor of AI was the elevated, although moderate, basal level of ACTH when the basal and stimulated cortisol were still normal. The glucocorticoid therapy improved fatigue in most patients.

Conclusions
Subclinical AI can be developed in > 50% of advanced thyroid cancer patients treated with TKI. This AE can develop in a wide period ranging from < 12 to > 36 months. For this reason, AI must be looked for throughout the follow-up to be early recognized and treated. A periodic ACTH stimulation test, every 6–8 months, can be helpful.
Evaluating signs of hippocampal neurotoxicity induced by a revisited paradigm of voluntary ethanol consumption in adult male and female Sprague-Dawley rats
Authors: Colom-Rocha Carles , Bis-Humbert Cristian , García-Fuster M. Julia 
Published: February 2023

Abstract
Background
Binge alcohol drinking is considered a prominent risk factor for the development of alcohol-use disorders, and could be model in rodents through the standard two-bottle preference choice test. The goal was to recreate an intermittent use of alcohol during 3 consecutive days each week to ascertain its potential impact on hippocampal neurotoxicity (neurogenesis and other neuroplasticity markers), and including sex as a biological variable, given the well-known sex differences in alcohol consumption.

Methods
Ethanol access was granted to adult Sprague–Dawley rats for 3 consecutive days per week, followed by 4 days of withdrawal, during 6 weeks, mimicking the most common pattern of intake in people, drinking over the weekends in an intensive manner. Hippocampal samples were collected to evaluate signs of neurotoxicity.

Results
Female rats consumed significantly more ethanol than males, although intake did not escalate over time. Ethanol preference levels remained below 40% over time and did not differ between sexes. Moderate signs of ethanol neurotoxicity were observed in hippocampus at the level of decreased neuronal progenitors (NeuroD + cells), and these effects were independent of sex. No other signs of neurotoxicity were induced by ethanol voluntary consumption when measured through several key cell fate markers (i.e., FADD, Cyt c, Cdk5, NF-L) by western blot analysis.

Conclusions
Overall, the present results suggest that even though we modeled a situation where no escalation in ethanol intake occurred across time, mild signs of neurotoxicity emerged, suggesting that even the use of ethanol during adulthood in a recreational way could lead to certain brain harm.
The Impact of a Dedicated Multidisciplinary Team Approach for Prosthetic Joint Infections of the Lower Limb
Authors: Sires James D. , Pham Kim , Wilson Christopher J. 
Published: February 2023

Abstract
Introduction
Prosthetic joint infections (PJI) of the hip and knee have significant morbidity and mortality, and present with varying local, host and microbiological factors. Given the broad presentation and complexity of PJI’s, we developed a dedicated multidisciplinary team (MDT) to manage this complex patient cohort, and report on our early outcomes.

Methods
This was a retrospective observational study of all patients diagnosed with a prosthetic joint infection of the hip or knee (n = 71) at our institution during a 4.5-year period. Patients treated after development of the MDT (post-MDT) (n = 44), were compared to a control group prior establishment of the MDT (pre-MDT) (n = 27).

Results
85.2% of individuals in the pre-MDT, and 85.7% of individuals in the post-MDT group were considered cured at a minimum 2 years post-operatively according to the Delphi-based definition. The total number of admissions to hospital (2.44 vs. 1.84) and total number of antibiotics used (3.37 vs. 2.75) decreased in the post-MDT group; however, differences were not considered statistically significant.

Discussion
Implementation of a dedicated MDT in the management of individuals with PJI’s of the lower limb at our hospital has allowed early and effective collaboration between healthcare personnel, with early promising results. Given the broad nature of PJI, future studies are ongoing to determine modifiable risk factors to reduce the incidence and improve outcomes of individuals with PJI’s where systems can then be implemented into already established MDTs to achieve the best clinical outcome for our patients.
Assessing the artificially intelligent workplace: an ethical framework for evaluating experimental technologies in workplace settings
Authors: Hosseini Ziagul , Nyholm Sven , Le Blanc Pascale M. , Preenen Paul T. Y. , Demerouti Evangelia 
Published: February 2023

AbstractExperimental technologies, including AI and robots, are revolutionising many types of work. For example, the logistics warehouse sector is witnessing a wave of new technologies, such as automated picking tools, collaborative robots and exoskeletons, affecting jobs and employees. Notably, it is not always possible to predict the effects of such new technologies, since they have inherent uncertainties and unintended consequences. Hence, their introduction into workplaces can be conceived as a social experiment. This paper aims to sketch a set of ethical guidelines for introducing experimental technologies into workplaces. It builds on Van de Poel's general framework for assessing new experimental technologies and translates that framework into a more specific context of work. We discuss its five principles: non-maleficence, beneficence, responsibility, autonomy, and justice. Each of these principles is applied to workplaces in general, and specifically to the logistics warehouse setting as a case study. A particular focus in our discussion is put on the distinctive potential harms and goods of work.
AllBRICQS: The All-sky BRIght, Complete Quasar Survey
Authors: Onken Christopher A. , Wolf Christian , Hon Wei Jeat , Lai (賴民希) Samuel , Tisserand Patrick , Webster Rachel 
Published: February 2023

AbstractWe describe the first results from the All-sky BRIght, Complete Quasar Survey (AllBRICQS), which aims to discover the last remaining optically bright quasars. We present 156 spectroscopically confirmed quasars (140 newly identified) having$|b|>10^{\circ}$. 152 of the quasars haveGaiaDR3 magnitudes brighter than$B_{P}=16.5$or$R_{P}=16$mag, while four are slightly fainter. The quasars span a redshift range of$z=0.07-3.93$. In particular, we highlight the properties of J0529-4351 at$z=3.93$, which, if unlensed, is one of the most intrinsically luminous quasars in the Universe. The AllBRICQS sources have been selected by combining data from theGaiaandWISEall-sky satellite missions, and we successfully identify quasars not flagged as candidates byGaiaData Release 3. We expect the completeness to be$\approx$96% within our magnitude and latitude limits, while the preliminary results indicate a selection purity of$\approx$96%. The optical spectroscopy used for source classification will also enable detailed quasar characterisation, including black hole mass measurements and identification of foreground absorption systems. The AllBRICQS sources will greatly enhance the number of quasars available for high-signal-to-noise follow-up with present and future facilities.
Can a urease inhibitor improve the efficacy of nitrogen use under perennial ryegrass temperate grazing conditions?
Authors: Murray Á. , Gilliland T. J. , Delaby L. , Patton D. , Creighton P. , Forrestal P. J. , McCarthy B. 
Published: February 2023

AbstractThis study sought to compare the efficiency of different nitrogen (N) fertilizer forms applied to perennial ryegrass swards that were rotationally grazed by dairy cows or sheep under Irish conditions for two or three years. A 3 × 2 factorial random complete block design plot arrangement was used to compare calcium ammonium nitrate (CAN), urea and urea + N-(n-butyl) thiophosphoric triamide (urea + NBPT) at 150 and 250 kg N/ha per year. Zero nitrogen plots were also added to allow for N efficiency to be calculated. The study was conducted at four sites, giving three years of data collection at two sites and two years at the other two sites. All four sites observed similar responses to N fertilizer type and N fertilizer rate. Significant differences were observed between the 150 kg N/ha and 250 kg N/ha treatments for pre-grazing herbage yield (1346 and 1588 kg DM/ha, respectively; P < 0.001) and total herbage production (12 290 and 14 448 kg DM/ha, respectively; P < 0.001). There was no difference but a tendency for pre-grazing herbage yield to be higher for CAN and urea + NBPT than urea (1485, 1480 and 1436 kg DM/ha, for CAN, urea + NBPT and urea, respectively; P = 0.091). Total herbage production was significantly higher for CAN and urea + NBPT than urea (13 478, 13 542 and 13 087 kg DM/ha, respectively; P = 0.004). In conclusion, there was an overall benefit detected over the 10 site-years from using urea protected with NBPT v. using urea.
The internal structure of the syllable in Russian and in Hebrew: Evidence from monolingual kindergarteners
Authors: Kogan Nadya , Saiegh-Haddad Elinor 
Published: February 2023

AbstractNotwithstanding remarkable phonological differences, the CV syllable is the most frequent syllable type in both Russian and Hebrew. This led to the prediction that the internal structure of the CVC syllable in the two languages, as reflected in phonological awareness tasks, might be similar. The study tested phonological awareness in two groups of monolingual kindergarteners: Hebrew-speaking (N = 35) and Russian-speaking (N = 20) in order to shed light on the underlying structure of the CVC syllable in the two languages. Phonological awareness tasks targeted awareness of the sub-syllabic structure (structured and unstructured) and phoneme awareness (initial and final). A linear mixed model analysis revealed that children in both groups showed greater facility with body-coda CV-C than with onset-rime C-VC syllable splitting and higher scores on final than on initial phoneme isolation tasks. The unstructured tasks also reflected the cohesion of the CV body in both languages. The findings demonstrate a similar internal representation of the CVC syllable in Russian and in Hebrew speakers as reflected in phonological awareness among preschoolers.
Farmer perceived challenges toward conservation practice usage in the margins of the Corn Belt, USA
Authors: Adhikari Ram Kumar , Wang Tong , Jin Hailong , Ulrich-Schad Jessica D. , Sieverding Heidi L. , Clay David 
Published: February 2023

AbstractWhile conservation practices promote soil health and reduce the negative environmental effects from agricultural production, their adoption rates are generally low. To facilitate farmer adoption, we carried out a survey to identify potential challenges faced by farmers regarding conservation tillage and cover crop adoption in the western margin of the US Corn Belt. We found farmers' top two concerns regarding conservation tillage were delayed planting, caused by slow soil warming in spring, and increased dependence on herbicide and fungicides. Narrow planting window and lack of time/labor were perceived by farmers as the two primary challenges for cover crop adoption. Some sense of place factors, including the commonly included dimensions of attachment, identity and dependence, played a role in farmers' perceived challenges. For example, respondents more economically dependent on farming perceived greater challenges. We found that farmers' challenge perceptions regarding reduced yield and lack of time/labor significantly decreased as years of usage increased, implying that time and experience could dilute some challenges faced by farmers. Our findings indicate that social network use, technical guidance and economic subsidies are likely to address the concerns of farmers and facilitate their adoption of conservation practices.
Dust Detection Over East Asia From Multispectral and Multi‐Temporal Himawari‐8/AHI Thermal Infrared Observations
Authors: Shi Jianjun , Yang Shizhi , Cui Shengcheng , Luo Tao , Li Xuebin , Lu Wenqiang , Han Lu 
Published: February 2023

AbstractThe frequent outbreak of dust storms every spring is one of the extreme weathers in East Asia. Geostationary meteorological satellite thermal infrared (TIR) imagery provides observations for high‐frequency, all‐day, large‐scale monitoring of dust sources and transport. This study proposes an integrated method to detect dust over East Asia by using the multispectral and multi‐temporal Himawari‐8/Advanced Himawari Imager (AHI) TIR observations, based on a Feedforward Neural Network (FNN) model and the Robust Principal Component Analysis based Anomalous Dust Detection (ADD) method. The FNN model is trained to map the multispectral Brightness Temperatures (BTs) to the three category probabilities (i.e., cloud, dust, and clear sky), and the ADD method calculates the dust score by normalizing multi‐temporal BT difference anomalous variation. The Integrated Dust Index (IDI) reflects the quantified dust confidence of the AHI pixel, which is defined as the sum of the dust probability and the dust score. The IDI was evaluated using 2 months of the Sentinel‐5P TROPOMI Ultraviolet Aerosol Index and achieved a total dust detection accuracy above 90%. A comparison with Cloud Aerosol Lidar and Infrared Pathfinder Satellite Observation nighttime observations shows that the IDI can also detect dust at night. The times series IDI of the massive 14–16 March 2021 dust storm show its capabilities to trace dust sources and monitor dust transport.
GOLD Synoptic Observations of Thermospheric Annual and Semiannual Variations in Composition During Solar Minimum Years
Authors: Gan Quan , Qian Liying , Pedatella Nicholas M. , Wu Yen‐Jung , Correira John , Wang Wenbin , McClintock William E. , Eastes Richard W. 
Published: February 2023

AbstractThis study investigates thermospheric seasonal variations composed of annual and semiannual oscillations (AO and SAO) in the column density ratio of atomic oxygen to molecular nitrogen observed by Global‐scale Observations of Limb and Disk. On the basis of multiple analysis approaches, it is revealed that the AO is the predominant component at middle latitudes, while the SAO tends to be increasingly important toward the lower latitudes. The SAO is also evident in the southern mid‐latitudes. Quantitative analyses demonstrate that AO (SAO) peaks around winter solstices (equinoxes). Additionally, the seasonal variation at low‐latitudes exhibits greater amplitudes in the early morning and around noon, whereas it gradually weakens from early morning toward late afternoon at mid‐latitudes. A hypothesis is that seasonal variations are likely modulated by atmospheric tides, including those generated in the thermosphere and those propagating upward from the lower atmosphere.
Role of Extreme Indian Ocean Dipole in Regulating Three‐Dimensional Freshwater Content in the Southeast Indian Ocean
Authors: Chen Gengxin , Han Weiqing , Ma Xueying , Li Yuanlong , Zhang Tiecheng , Wang Dongxiao 
Published: February 2023

AbstractThe tropical Southeast Indian Ocean (SEIO) is a key area linking the global freshwater and heat exchanges. The Indian Ocean Dipole (IOD) fundamentally modulates the Indian Ocean circulation and thus regulates the basin‐wide freshwater balance. However, our knowledge of this effect remains limited. Using observational‐based data sets, this study suggests that extreme positive IOD events have notable signatures on the three‐dimensional freshwater content of the SEIO, leading to the vertically opposite salinity anomalies in the surface and subsurface layers. The wind changes led to the northwestward extension of the South Equatorial Current and intensified Sumatra‐Java upwelling. The changing horizontal and vertical currents jointly result in the complicated salinity anomalies. The Equatorial Undercurrent serves as the conduit for water exchange between the equator and the SEIO. This work highlights a strong coupling between the equatorial circulation and the three‐dimensional freshwater inventory of the SEIO within the framework of the IOD.