bluuebunny/crossref_metadata_2025_split huggingface dataset:
Merchant estates in Tomsk planning structure late in the 19th and early 20th centuries
Authors: Katalevskaya E. S. , Sitnikova E. V. 
Published: February 2023

The article deals with wooden merchant estate buildings of Tomsk late in the 19th and early 20th centuries. At the turn of the 19–20th centuries, the wooden construction, is the fundamental planning in the architectural and town-planning structures in Siberian cities. The relevance of the study is determined by the problems of preserving the integrity of historical urban estates in Tomsk, in particular household buildings of which there are currently very few left.Purpose: A comprehensive analysis of three most interesting estates of Tomsk merchants, namely G.M. Golovanov, A.F. Zelenevskaya, and the Kukhterins and the planning structure and functional zoning of merchant estates, architecture and planning of buildings, and preservation of estate complexes.Methodology/approach: Historical, archival and bibliographic documents; field research conducted by the authors in 2022; methods of the data identification, comprehensive, systematic and comparative analyses.Research findings: Collected and analyzed materials on wooden merchant estates in Tomsk. The high urban significance of the historical buildings is determined, the rational zoning and multifunctionality of merchant estates is identified.Originality/value: The comprehensive analysis of three merchant wooden estates of the 19–20th centuries, justification of their value as the main elements of the spatial planning structure of the Tomsk city.
Symptomatic subdural hemorrhage following heart valve surgery: a retrospective cohort study
Authors: Oshida Sotaro , Tsuboi Junichi , Kin Hajime , Okabayashi Hitoshi , Komoribayashi Nobukazu , Akamatsu Yosuke , Fujiwara Shunrou , Ogasawara Kuniaki 
Published: February 2023

OBJECTIVE
Subdural hemorrhage (SDH) has been reported to be the most frequent intracranial hemorrhagic complication following open heart surgery; however, its clinical features and pathophysiology remain unclear. The aim of this retrospective study was to elucidate the incidence, clinical course, and factors associated with the development of symptomatic SDH following heart valve surgery.

METHODS
A retrospective review of medical records on the development of symptomatic SDH after heart valve surgery involving cardiopulmonary bypass (CPB) from April 2011 to March 2016 was performed. Patients who had undergone preoperative cranial computed tomography (CT) or brain magnetic resonance imaging (MRI) were included in this study, and factors associated with SDH following heart valve surgery were analyzed. When neurological symptoms developed after heart valve surgery, cranial CT or brain MRI was performed.

RESULTS
A total of 556 patients who had undergone heart valve surgery were analyzed. Among these patients, symptomatic SDH occurred in 11 (2.0%). The mean duration of symptomatic onset was 10.1 days (range 2–37 days). Ten of 11 patients (90.9%) developed SDH in the posterior fossa or occipital convexity. Logistic regression analysis revealed longer aortic clamp time (95% CI 1.00–1.10, p = 0.04), higher dose of heparin after surgery (95% CI 1.00–1.02, p = 0.001), and higher pulmonary artery pressure (PAP) just before disconnection of the CPB (95% CI 1.01–1.37, p = 0.04) as significantly associated with the development of SDH.

CONCLUSIONS
The incidence of symptomatic SDH following heart valve surgery was 2.0%. Symptoms due to SDH usually developed a few days to 1 month after surgery. Surprisingly, most SDHs developed in the posterior fossa or occipital convexity following heart valve surgery. A longer aortic clamp time, higher dose of heparin after surgery, and higher PAP just before disconnection of the CPB were related to the development of symptomatic SDH following heart valve surgery.
Efektifitas Hipnoterapi Dalam Menurunkan Tingkat Kecemasan Pasien Gangguan Jiwa
Authors: Putri Puspitasari Rahmah , Mufidah Wardatul , Zunaidah Siti Nur 
Published: February 2023

The purpose of this study is to determine the effectiveness of hypnotherapy in decreasing anxiety levels in mental disorder patients.The hypothesis proposed is to find out whether hypnotherapy reduces the level of anxiety of mental disorder patients.The samples from this study involved 18 patients from Puskesmas II Denpasar Timur Bali.The sampling technique used in this study was Purposive Sampling. To obtain an anxiety score in this study, the method of data collection with observation, interview, hars psychology scale (Hamilton Anxiety Rating Scale) by testing anxiety scores using hypnosis therapy. The hypothesis test used is a paired samples statistical test. The results of the t-test analysis use paired sample test sign values. 2 tailed of : 0.002 and paired sample correlation value : 0.262 with mean pretest : 21.83 and mean post test : 18.44. with the conclusion of the value of the sig. the difference test gets a value of 0.000. The value is less than 0.05. This shows that there is a significant difference in the level of anxiety between before and after hypnotherapy, where there is a decrease in anxiety between before hypnosis and after hypnosis. So the proposed hypothesis is accepted.

Key words : anxiety, hypnotherapy, mental disorder patient
НОВА РОЗРАХУНКОВА МЕТОДИКА МОДЕЛЮВАННЯ СТРУГАННЯ МЕТАЛУ
Authors: Паровченко М. В. , Нарижний О. Г. 
Published: February 2023

Cutting methods on machine-building enterprises have a stake of 50-70% of machining total volume. Hereupon, especially taking into account the use of new materials, new modes of cutting and new equipment, cutting tasks on the increase of the productivity, part processing accuracy, durability and strength of instrument, efficiency of equipment will be yet long time actual. In this connection there is a requirement in the methods of research of cutting processes. It is confessed that the experimental method of decision of cutting tasks almost exhausted the possibilities, that is why it is needed to develop theoretical approach that has two basic directions. The first direction is a-the construction of analytical correlations that describe relationship of cutting parameters and allow to expect the necessary values of parameters in every case, on the basis of generalization of statistical data or on the basis of suppositions. The second direction envisages formulation and decision of tasks of cutting on the basis of the use of fundamental laws of mechanics of the deformed solid. In this direction an important role is played by the method of finite elements. In our time three varieties of FEM are used for the simulation of cutting with dissociating of chip from a detail: method of Euler, method of Lagrange and ALE (arbitrary Lagrangian- Eulerian). Each of varieties has substantial disadvantages. The methods of Euler and ALE need preliminary determination of form of body of chip and used for the calculations of the regular modes of cutting. The method of Lagrange needs the use of adaptive nets and "throwing" out of erosion elements, that causes violation of balance of mass and energy are executed in that. Besides all these methods have too high cost The new methods of discretization of differential equalizations appear in our time, in particular, SPH (smooth particle hydraulic), that is free of the indicated defects. This method is potentially free of the indicated defects. It was used for the decision of similar tasks. The article contains mathematical problem of cutting definition, description of calculation model, discretization of FEM-SPH mixed in particular, and also results.
СИСТЕМА ФОРМУВАННЯ ЗНАНЬ ІНФОРМАЦІЙНОЇ ПІДГОТОВКИ ПРОФЕСІОНАЛІВ-ФАХІВЦІВ З ЕКОНОМІКИ ТА УПРАВЛІННЯ ГОСПО-ДАРСЬКОЮ ДІЯЛЬНІСТЮ ПІДПРИЄМСТВ АВІАЦІЙНОЇ ГАЛУЗІ ПРИ ПЕРЕХОДІ УКРАЇНИ ДО РИНКОВОЇ ЕКОНОМІКИ
Authors: Бабушкин А. И. , Бабушкин А. А. 
Published: February 2023

The concept of organizing the process of forming the composition of academic disciplines and curricula for teaching KhAI students is outlined in the training of specialists in the new formation in economics and management of enterprises in the aerospace industry in connection with the transition of Ukraine from a command-administrative system to a market-entrepreneurial form of management.At the time of the proclamation of Ukraine as an independent state, the aerospace industry, at the scientific, technical and technological level of creating advanced designs of aircraft and rocket and spacecraft, occupied one of the foremost places in the world. Having made a choice in favor of the transition to a market economy, Ukraine has set itself the task of great organizational complexity - how to maintain the achieved scientific and technical level in the new market conditions of economic activity of enterprises to achieve high economic results?The key issue is the training of personnel in a new formation based on new knowledge at all levels of the full-time economic positions of the enterprise. The analysis of new functional responsibilities for professional specialists allowed:– to form the composition and content of the disciplines to be studied for the new conditions of economic activity of the enterprise,– develop curricula and related provisions for the organization of the educational process, taking into account the use of modern integrated information technologies,– prepare the necessary teaching materials (manuals, recommendations, instructions),– organize specialized training classes equipped with modern computer technology with the availability of work on the international Internet.The concept of curriculum formation and the methodology for filling them with a set of focused disciplines (what to teach), supported by appropriate teaching and methodological tools for teaching them (how to teach) met the expectations of training high-quality professional economists to work in a market economy.
ДОСЛІДЖЕННЯ ЛОГІСТИЧНИХ ПРОЦЕСІВ ПРИ ВИРОБНИЦТВІ ТЕХНІЧНО-СКЛАДНОЇ ПРОДУКЦІЇ
Authors: Rudenko N. 
Published: February 2023

Automation of production processes, which is widely used at foreign enterprises and largely reduces the labor intensity of products, is of particular relevance. In addition, in some cases, the installation of more productive equipment leads to a reduction in its quantity and allows you to partially free up production space. Technical re-equipment should concern, first of all, those workshops and production areas where cost reduction will be of greatest importance.The reasons for the need for technical re-equipment of small machining enterprises can be grouped in the following areas:- increasing the technological stability of production;- reduction of production cycles of parts and assembly units, acceleration of the turnover of investments;- reduction of terms and cost of preparation of production;- reduction of labor intensity, reduction of production costs;- reduction of rejects and costs for the restoration of defective products;- reducing the cost of upgrading and repairing equipment.The success of the enterprise, its competitiveness in market conditions, largely depends on how the issue of managing costs in the process of production and sale of products is resolved. It is especially important to re-solve this issue in the case of a diversified nature of production. The research methodology in this work will be the use of the SMED equipment changeover system to save time in the production of multi-product parts. If the changeover process takes very little time, it can be carried out as often as required. This, in turn, means that if we manufacture products in small batches, we can get many advantages: flexibility, fast delivery, productivity, high quality.The enterprise can meet the changing needs of customers without the overhead of stockpiling. Manufacturing in small batches will reduce the time spent preparing the order for shipment, as well as the time the customer waits for the required product. Accordingly, the likelihood of damage to products is reduced, since their stor-age time is reduced. The volume of production rejects is also reduced due to fewer errors during setup and trial runs of equipment.
Geometric Evaluation and Analysis of Road Pavement on the Buper - Kemp Road Section, Wolker Waena
Authors: Widy Christianto Silamba  , Iskandar Isdaryanto 
Published: February 2023

The topography in Jayapura regency is generally an area consisting of mountains and valleys that have various elevations, and the transportation facilities are also diverse. Geometric evaluation on the Camp road section. Wolker – Buper Waena conducted a topographic survey of existing roads. To obtain geometric data, then geometric evaluation is carried out based on RSNI T-14-2004 (Guidelines for Geometric Planning of Urban Roads) and Inter-City Geometric Planning Procedures, Department of PU, Directorate General of Highways, 1997. Road pavement analysis based on the Road Pavement Design Manual of the Ministry of PU No. 04/SE/DB/2017 and the Regulation of the Minister of PU No. 04/SE/M/2010.The conclusion of the study on geometric evaluation of horizontal alinyemen roads on the bends PI – 10 and PI – 11 did not meet the standard provisions. Similarly, vertical alinyemen exceeds the maximum limit of road slump, which is 10%. The slump is at sta 0+450 – 0+650 and sta 0+800 – 1+400. Thus, it needs re-planning. Analysis of road pavement at the Cbr point of the field > 6%, the basic soil strength class SG6. Basic soil improvement foundation structure stabilization segment or preferred heap material (compaction of ≤ layer 200 mm loose thickness), no need for improvement. Then for the field Cbr < 2.5%, the basic soil strength class SG1 with a support layer of 700 mm. For a field Cbr of 2.5%, the base soil strength class is SG2.5 with a minimum soil improvement thickness of 175 mm. For field Cbr, 3 % uses basic soil strength class SG3 with a minimum thickness of soil improvement of 150 mm. For a field Cbr of 4%, a base soil strength grade of SG4 with a minimum soil improvement thickness of 100 mm. The pavement layer design obtained AC WC = 40 mm, AC BC = 60 mm and LPA Class A adjusts the minimum thickness of soil improvement of each segment.
Pengaruh Ekstrak Etanol Kunyit (Curcuma longa) terhadap Pembentukan Biofilm Candida albicans
Authors: Fauzan Laili Shafarina , Masfufatun Masfufatun , Inawati Inawati 
Published: February 2023

Abstrak
Kunyit (curcuma longa) merupakan salah satu jenis tanaman yang memiliki zat bioaktif yang dapat menghambat jamur. Penelitian ini bertujuan untuk mempelajari aktivitas antibiofilm ekstrak kunyit yang dapat menghambat pertumbuhan biofilm Candida albincans. Jenis penelitian menggunakan eksperimental labolatorik secara in vitro dengan rancangan penelitian post-test only control group. Kunyit dimaserasi dengan pelarut etanol. Ekstrak dibuat menjadi konsentrasi 1%; 0,5%; 0,25%; 0,125% dan 0,625%. Uji antibiofilm menggunakan metode mikrodilusi yang diawali dengan tahap adherent sel dan ditambahkan kristal violet 0,01% untuk pengukuran matriks biofilm C.albicans melalui microplate reader (λ = 490 nm) dan dihitung nilai absorbansinya. Data dianalisis dengan menggunakan ANOVA satu arah One Way Analysis of Varians) dengan taraf kepercayaan 5%, kemudian dilanjutkan dengan uji LSD. Hasil penelitian menunjukkan konsentrasi ekstrak kunyit 1%; 0,5%; 0,25%; 0,125% dan 0,625% memiliki kemampuan sebagai antibiofilm dengan persentase penghambatan masing-masing sebesar 70,595; 63,413; 56,4785; 48,764 dan 34,043%. Berdasarkan analisis probit, diperoleh nilai KHBM50 ekstrak kunyit sebesar 0,546%. Dapat disimpulkan bahwa ekstrak etanol kunyit memiliki kemampuan dalam menghambat pertumbuhan biofilm Candida albicans sehingga bisa dimanfaatkan sebagai agen alternatif antibiofilm.
Kata kunci: ekstrak kunyit (Curcuma longa), antibiofilm, Candida albicans

Abstract
Turmeric (curcuma longa) is one type of plant that has bioactive substances that can inhibit fungi. This study aims to evaluate the antifungal and antibiofilm activity of turmeric extract as that can inhibit the growth of the fungus Candida albincas. This research used laboratory experimental in vitro with a post-test only control group research design. Turmeric macerated with ethano. Extracts were made into concentrations of 1,0; 0,5: 0,25; 0,125 and 0,625%. Antibiofilm test used microdilution method, starting with the adheren cell stage and adding crystal violet 0.01% for testing. Then it was observed using a microplate reader (λ = 595 nm) and absorbance value was calculated. The data were analyzed using one-way ANOVA (One Way Analysis of Variance) with a 5% confidence level, then continued with LSD test. The results showed that the concentration of turmeric extract 1,0; 0,5: 0,25; 0,125 and 0,625% had the ability as antibiofilm with the percentage inhibition of 54,9; 52,16; 49,28; 12,89 and 15,98%, respectively. Based on probit analysis, the KHBM50 value was 0.546%. Based on this research, it can be concluded that turmeric extract has ability to inhibit the growth of Candida albicans so that it can be used as an alternative antibiofilm agent.
Keywords: turmeric extract (Curcuma longa), antibiofilm, Candida albicans
ДОСЛІДЖЕННЯ ШЛЯХІВ ЗМЕНШЕННЯ ЗАБРУДНЕННЯ ПОВІТРЯ ВІД СУДНОПЛАВСТВА
Authors: Golovan A.I. , Honcharuk I.P. , Voloshyn A.O. , Shumylo O.M. , Nykyforov Yu.O. , Shamov O.V. 
Published: February 2023

У статті розглядаються сучасні проблеми запобігання забруднення повітря в процесі експлуатації судна. Вказані проблеми зумовлені тим, що викиди вуглекислого газу сприяють глобальному потеплінню, а гази оксидів сірки і оксидів азоту швидко перетворюються на кислотні речовини, які впливають на хімічний склад морських, поверхневих вод та ґрунту, що має наслідки для організмів, які населяють підкислену воду. Всі фізіологічні і ферментативні процеси є чутливими до водневого показнику і, отже, можуть мати великий вплив, наприклад, на ріст мікроорганізмів, а також на більших тварин, наприклад, впливаючи на відчуття і органи нюху живих організмів. В теперішній час національні та міжнародні екологічні норми визначають необхідність покращення стану навколишнього середовища. Проведений аналіз попередніх досліджень і публікацій свідчить про те, що питанням визначення оптимального способу запобігання забруднення повітря в процесі експлуатації судна не приділено належної уваги. З огляду на прогнозування очікування збільшення глобальних морських перевезень приблизно на 3 % на рік з 2021 по 2030 рік через економічне зростання та сприяння морському транспорту, цей прогноз формує необхідність аналізу та застосування дієвих засобів запобігання забруднення повітря. Метою статті є аналіз динаміки забруднення повітря від судноплавства і визначенні оптимального способу запобігання забруднення повітря в процесі експлуатації судна. А також аналіз нормативно правової бази, що регулює питання запобігання забруднення повітря і аналіз існуючих способів запобігання забруднення повітря в процесі експлуатації судна. Результати. Запропоновані заходи та надані рекомендації щодо вибору оптимального способу запобігання забруднення повітря в процесі експлуатації судна. Висновки. Таким чином, проблеми запобігання забруднення повітря в процесі експлуатації судна повинні вирішуватися в комплексі, з урахуванням того, що найефективнішими, менш витратними, такими, що не потребують значної модернізації самого судна, є наступні способи запобігання забруднення повітря: очищення відпрацьованих газів, їх рециркуляція, попередня обробка палива і застосування емульсій води та палива.
СУЧАСНИЙ МЕТОД РОЗРАХУНКУ ПОПРАВКИ КОМПАСУ ПО НЕБЕСНИМ ТІЛАМ З ВИКОРИСТАННЯМ СЕРЕДОВИЩА MATLAB
Authors: Kupraty O.G. 
Published: February 2023

В сучасних умовах зростає роль інформаційних технологій для безпечної навігації. У статті опрацьовується метод розрахунку поправки компасу через взаємодію програмного середовища MATLAB та програмного середовища MS Excel. Сучасна навігація потребує нових підходів до розв’язання задачі розрахунку поправки компасу по небесним тілам. Для реалізації цих підходів автором було розроблено алгоритм і прописано код у вище зазначеному програмному середовищі. Програмне середовище MATLAB дозволяє брати дані з електронного астрономічного альманаху і опрацьовувати їх в автоматичному режимі згідно алгоритму. Велике значення приділено знакам параметрів A і B. В програмному коді прописано умови вибору знаку для параметру A за широтою, для параметру B за місцевим часовим кутом LHA та схиленням DEC. У роботі було використано альманах у форматі в MS Excel. Аналізуючи альманах, було розроблено алгоритм, що відштовхується від зимового і літнього сонцестояння, тобто 2 схилення, 2 точки, від яких змінюється напрям графіку схилення від зростання на спадання і навпаки. Сонцестояння – момент часу, у який центр Сонця проходить або через найпівнічнішу точку екліптики, що має схилення +23° 27', або через найпівденнішу її точку, що має схилення -23° 27'. В алгоритмі використовуються 5 дат: сонцестояння минулого року, 2 сонцестояння року, в якому відбулася обсервація, день обсервації і останній день року. Дані по Сонцю в день обсервації комбінуються в матриці, з яких потім вибирається необхідне значення.
The Use of Antibiotics without a Prescription : a Literature Review
Authors: Dewi Arie Kusumo , Handayani Handayani , Febriani Afira 
Published: February 2023

Background : Infectious diseases are treated with antibiotics. Antibiotics are widely used because infectious diseases are so common. Even though antibiotics are purchased at pharmacies with a doctor's prescription, many antibiotics are currently being taken without a prescription. Resistance will develop if antibiotics are consumed without a doctor's prescription and not according to indications for administration.
Objective : This study examines how people use antibiotics without a doctor's prescription.
Methods : The author of this article uses a method related to the article's title by using some relevant literature from database of journals such as Google Scholar. The discussion and findings of this study will assist readers and health professionals in analyzing how people use antibiotics without a prescription.
Result : Based on the findings of the five studies, journals discuss the relationship between knowledge level and attitudes regarding the use of antibiotics without a prescription. This literature review shows that most people of reproductive age consume antibiotics without a doctor's prescription to treat symptoms usually caused by non-bacterial pathogens.
Conclusion : . One of the intervention approaches taken to restrict access is government control. Holistic interventions against those who sell antibiotics without a prescription are expected to significantly reduce the irresponsible use of antibiotics in the community
Drug Interactions in Coronary Heart Disease Patients : a Literature Review
Authors: Tamarah Elok , Handayani Handayani , Ferdiantoro Andik 
Published: February 2023

Background: Patients with coronary heart disease generally receive many drugs, such as hypercholesterolemia, antianginal, antiplatelet, anticoagulants, and medications for comorbid illnesses such as antihypertension and diabetes mellitus. Concomitant administration of several types of drugs may result in drug interactions.
Objective : This study aims to figure out drug interactions that might occur in using combination drugs in patients with coronary heart disease.
Methods: This article review uses the Google Scholar database, published 2017-2022. The keywords used were "coronary heart disease and drug interactions." The PRISMA flowchart is used to summarize the article selection process.
Results: Administration of aspirin with clopidogrel causes a moderate synergistic interaction, whereas administration of antiplatelet agents with anticoagulants causes a significant synergistic interaction on bleeding. And the administration of nifedipine with atorvastatin causes a synergistic pharmacodynamic interaction.
Conclusions: Drug interactions occur in patients with coronary heart disease, either synergistic or antagonistic pharmacodynamic interactions with minor, moderate, and significant classifications