bluuebunny/crossref_metadata_2025_split huggingface dataset:
Persepsi Terhadap Penggunaan Istilah Penyuntingan Berbahasa Melayu dalam Kalangan Pensyarah Bidang Penerbitan
Authors: Suhaimi Mohamad Suhaizi , Sharif Muhammad Ridzwan 
Published: June 2023

Penggunaan istilah dalam bidang penyuntingan naskhah sering menimbulkan kekeliruan apabila pengguna bahasa perlu memilih sama ada ingin menggunakan bahasa pinjaman atau bahasa Melayu asli. Oleh itu, kajian ini bertujuan mengenal pasti istilah-istilah penyuntingan dalam bahasa Melayu asli di samping menganalisis persepsi para pensyarah terhadap penggunaan istilah penyuntingan berbahasa Melayu asli. Kajian ini menggunakan kaedah bertanyakan soalan (naming questions) yang bertumpukan kepada persoalan kajian dalam mengkaji persepsi responden terhadap istilah penyuntingan berbahasa Melayu. Selain itu, kajian ini menggunakan kaedah kualitatif serta instrumen soal selidik yang melibatkan empat (4) orang pensyarah universiti sebagai responden yang dipilih melalui persampelan bertujuan (purposive sampling) supaya bertepatan dengan ciri-ciri yang dikehendaki oleh pengkaji. Dapatan kajian mengenai persepsi seperti ‘menggunakan’, ‘menggalakkan’, ‘faham’ dan ‘sikap’ menunjukkan bahawa istilah penyuntingan berbahasa Melayu digunakan sepenuhnya dalam kalangan responden. Selain itu, kecenderungan responden dalam menggunakan istilah-istilah penyuntingan berbahasa Melayu asli juga memaparkan jumlah yang tinggi. Justeru, para pensyarah dalam bidang penyuntingan bahasa Melayu tidak mempunyai persepsi yang negatif terhadap penggunaan istilah penyuntingan berbahasa Melayu asli.

Daunting decision in the field of manuscript editing happened when choosing either to use borrowed words or the original Malay language. Therefore, this study aims to identify the terms of editing in the original Malay language as well as to analyse the perceptions of lecturers on the use of editing terms in the original Malay language. This study uses the method of naming questions which focuses on research questions in examining respondents' perceptions of the term Malay language editing. In addition, this study uses qualitative method and questionnaire instruments involving four (4) university lecturers as respondents selected through purposive sampling to coincide with the characteristics desired by the researcher. Findings of the study on perceptions such as ‘use’, ‘encourage’, ‘understand’ and ‘attitude’ show that the term Malay language editing is used fully among the respondents. Besides, their tendency in using original Malay language editing terms also displays a high number. Thus, the lecturers in the field of Malay language editing do not have a negative perception on the use of the term original Malay language editing.
Measurement properties of utility-based health-related quality of life measures in cardiac rehabilitation: a systematic review protocol
Authors: Bulamu Norma B. , Hines Sonia , Gebremichael Lemlem G. , Mpundu-Kaambwa Christine , Pinero de Plaza Maria Alejandra , Dafny Hila A. , Beleigoli Alline , Kaambwa Billingsley , Hendriks Jeroen M. , Clark Robyn A. 
Published: June 2023

Objective:
This review will identify and appraise existing evidence on the measurement properties of utility-based health-related quality of life (HRQoL) measures used in cardiac rehabilitation programs. The review will then map the measure domains against the International Classification of Functioning, Disability and Health and the International Consortium of Health Outcome Measures domains for cardiovascular disease.

Introduction:
Improving HRQoL is an international key indicator for delivering high-quality and person-centered secondary prevention programs. Many instruments and measures assess HRQoL in individuals undergoing cardiac rehabilitation. Utility-based measures are suitable for calculating quality-adjusted life years, a required outcome metric in cost–utility analysis. Cost–utility analysis requires the use of utility-based HRQoL measures. However, there is no consensus on which utility-based measure is best for populations undergoing cardiac rehabilitation.

Inclusion criteria:
Eligible studies will include patients aged ≥ 18 years with cardiovascular disease who are undergoing cardiac rehabilitation. Empirical studies that assess quality of life or HRQoL using a utility-based, health-related, patient-reported outcome measure or a measure accompanied by health state utilities will be eligible. Studies must report at least 1 of the following measurement properties: reliability, validity, responsiveness.

Methods:
This review will follow the JBI methodology for systematic reviews of measurement properties. The following databases will be searched from inception to the present: MEDLINE, Emcare, Embase, Scopus, CINAHL, Web of Science Core Collection, Informit, PsyclNFO, REHABDATA, and the Cochrane Library. Studies will be critically appraised using the COSMIN risk of bias checklist. The review will be reported in line with the PRISMA guidelines.

Systematic review registration number:
PROSPERO CRD42022349395
Mites associated with Vitis labrusca (Vitaceae) in southern Brazil: Population dynamics and ecology
Authors: Da Silva Rita Tatiane leão , Berté Amália Luisa Winter , Bizarro Gabriel Lima , Schussler Matheus , Silva Darliane Evangelho , Granich Juliana , Ferla Noeli Juarez 
Published: June 2023

Viticulture is one of the main economic activities in Rio Grande do Sul (RS), Brazil, with emphasis on the American grape varieties, Vitis labrusca L. (Vitaceae), used in producing juices and wines. The present work aimed to identify the mite species associated with American grapevines (V. labrusca), their possible natural enemies, and their population fluctuations. The selected varieties were: Bordô (Bd) and Couderc (Cc and Cd) in Dois Lajeados (RS), Bordô (Bi) in Imigrante (RS) and Bordô (Bp), in Putinga (RS). The study was conducted monthly between March 2017 and March 2018, evaluating 20 randomly selected plants from each municipality. We found 5,452 mites belonging to 13 families, distributed across 29 genera and 42 species, or belonging to the suborder Oribatida. Higher mite richness was observed on Cc (12 species) and higher abundance on Cd (2,812 specimens), Cc (868) and Bi (799). Among the predatory mite families, Stigmaeidae had the highest abundance (896 specimens), followed by Phytoseiidae (746). The most abundant species observed were Euseius mesembrinus (Dean), Agistemus riograndensis Johann & Ferla, Tydeus californicus (Banks), Polyphagotars-onemus latus (Banks) and Tarsonemus sp. This is the first study in southern Brazil that evaluates and reports the mite fauna and its ecology on American grape varieties, with high abundance and frequency of predatory mites. This work is important to assist in implementing management techniques that promote the maintenance of predatory mite species in these vineyards.
Measles, mumps, and rubella vaccine at age 6 months and hospitalisation for infection before age 12 months: randomised controlled trial
Authors: Zimakoff Anne Cathrine , Jensen Andreas , Vittrup Dorthe Maria , Herlufsen Emma Hoppe , Sørensen Jesper Kiehn , Malon Michelle , Svensson Jannet , Stensballe Lone Graff 
Published: June 2023

Abstract

Objective
To test for potential non-specific effects of an additional, early measles, mumps, and rubella (MMR) vaccine at age 5-7 months on risk of infection related hospitalisation before age 12 months.

Design
Randomised, double blinded, placebo controlled trial.

Setting
Denmark, a high income setting with low exposure to MMR.

Participants
6540 Danish infants aged 5 to 7 months.

Interventions
Infants were randomly allocated 1:1 to intramuscular injection with standard titre MMR vaccine (M-M-R VaxPro) or placebo (solvent only).

Main outcome measures

Hospitalisations for infection, defined as all hospital contacts of infants referred from primary care for hospital evaluation and with an infection diagnosed, analysed as recurrent events, from randomisation to 12 months of age. In secondary analyses implications of censoring for date of subsequent diphtheria, tetanus, pertussis, polio,
Haemophilus influenzae
type B, and immunisation with pneumococci conjugate vaccine (DTaP-IPV-Hib+PCV), potential effect modification by sex, prematurity (<37 weeks’ gestation), season, and age at randomisation were tested, and the secondary outcomes of hospitalisations ≥12 hours and antibiotic use were evaluated.

Results
6536 infants were included in the intention-to-treat analysis. 3264 infants randomised to MMR vaccine experienced 786 hospitalisations for infection before age 12 months compared with 762 for the 3272 infants randomised to placebo. In the intention-to-treat analysis the rate of hospitalisations for infection did not differ between the MMR vaccine and placebo groups (hazard ratio 1.03, 95% confidence interval 0.91 to 1.18). For infants randomised to MMR vaccine compared with those randomised to placebo, the hazard ratio of hospitalisations for infection with a duration of at least 12 hours was 1.25 (0.88 to 1.77), and for prescriptions of antibiotics was 1.04 (0.88 to 1.23). No significant effect modifications were found by sex, prematurity, age at randomisation, or season. The estimate did not change when censoring at the date infants received DTaP-IPV-Hib+PCV after randomisation (1.02, 0.90 to 1.16).

Conclusion
Findings of this trial conducted in Denmark, a high income setting, do not support the hypothesis that live attenuated MMR vaccine administered early to infants aged 5-7 months decreases the rate of hospitalisations for non-targeted infection before age 12 months.

Trial registration

EU Clinical Trials Registry EudraCT 2016-001901-18 and ClinicalTrials.gov
NCT03780179
.
Relationship between job stress and work-related quality of life among emergency medical technicians: a cross-sectional study
Authors: Hashemi Shima , Ghazanfari Firoozeh , Merzah Mohammed , Rezaei Mehdi , Astaraki Peyman , Birjandi Mehdi 
Published: June 2023

ObjectiveThis study was aimed to determine the relationship between job stress and work-related quality of life (WRQoL) among emergency medical technicians (EMTs) in Lorestan province, Western Iran.DesignThis was a cross-sectional study.MethodsTotally 430 EMTs who had been engaged in their respective units for more than 6 months from all emergency facilities in Lorestan province were selected using single stage cluster sampling method. Data were collected from April to July 2019 using two standard questionnaires: job stress (Health and Safety Executive (HSE)) and WRQoL. The OR with 95% CI was used to declare the statistical association (p≤0.05).ResultsAll participants were exclusively males, with a mean age of 32±6.87 years. The overall average score of job stress using the HSE scale was 2.69±0.43; while the overall quality of working life score was 2.48±1.01. The type of working shift was found to have a significant impact on the HSE-average score (F(3,417)=5.26, p=0.01); and on the WRQoL-average score (F(3,417)=6.89, p<0.01).ConclusionTwo-thirds of EMTs working in governmental hospitals had job stress and a low quality of work-related life. Additionally, work shift was statistically significant associated with EMTs’ job stress and WRQoL.
Novel sequential treatment strategy for patients with muscle-invasive bladder cancer (MIBC): intravesical recombinant BCG, followed by neoadjuvant chemoimmunotherapy, radical cystectomy plus pelvic lymphadenectomy and adjuvant immunotherapy – protocol of a multicentre, single arm phase 2 trial (SAKK 06/19)
Authors: Petrausch Ulf , Spahn Martin , Schneider Martina , Hayoz Stefanie , Rentsch Cyrill A , Rothschild Sacha , Omlin Aurelius , Cathomas Richard 
Published: June 2023

IntroductionThe combination of checkpoint inhibition and cisplatin-based chemotherapy is investigated in muscle invasive bladder cancer (MIBC) and results from phase 2 trials have been presented. Intravesical BCG has been used for non-MIBC (NMIBC) in patients with carcinoma in situ and high-grade Ta/T1 tumours. BCG induces innate and adapted immune response and upregulation of PD-L1 in preclinical models. The proposed trial is intended to implement a new immuno-immuno-chemotherapy induction therapy for MIBC. The combination of BCG and checkpoint inhibition with chemotherapy aims at higher intravesical responses and better local and systemic control of disease.Methods and analysisSAKK 06/19 is an open-label single-arm phase II trial for patients with resectable MIBC T2-T4a cN0-1. Intravesical recombinant BCG (rBCG: VPM1002BC) is applied weekly for three instillations followed by four cycles of neoadjuvant cisplatin/gemcitabine every 3 weeks. Atezolizumab 1200 mg every 3 weeks is started together with rBCG and given for four cycles. All patients then undergo restaging and radical cystectomy and pelvic lymphadenectomy. Atezolizumab is continued as maintenance therapy after surgery every 3 weeks for 13 cycles. Pathological complete remission is the primary endpoint. Secondary endpoints include pathological response rate (<ypT2 N0), event-free survival, recurrence-free survival, overall survival, feasibility and toxicity. An interim safety analysis will be performed after the first 12 patients have completed neoadjuvant treatment specifically assessing toxicity possibly associated with intravesical rBCG application.The study has received approval by ethical committee Zurich, Switzerland, BASEC-No. 2021–01872. Results will be made available by publication.Trial registration numberNCT04630730.
Protocol for improving the costs and outcomes of assistive reproductive technology fertility care pathways: a study using cost measurement and process mining
Authors: Leusder Maura , van Elten Hilco J , Ahaus Kees , Hilders Carina G J M , van Santbrink Evert J P 
Published: June 2023

IntroductionValue-based healthcare suggests that care outcomes should be evaluated in relation to the costs of delivering that care from the perspective of the provider. However, few providers achieve this because measuring cost is considered complex and elaborate and, further, studies routinely omit cost estimates from ‘value’ assessments due to lacking data. Consequently, providers are currently unable to steer towards increased value despite financial and performance pressures. This protocol describes the design, methodology and data collection process of a value measurement and process improvement study in fertility care featuring complex care paths with both long and non-linear patient journeys.Methods and analysisWe employ a sequential study design to calculate total costs of care for patients undergoing non-surgical fertility care treatments. In doing so, we identify process improvement opportunities and cost predictors and will reflect on the benefits of the information generated for medical leaders. Time-to-pregnancy will be viewed in relation to total costs to determine value. By combining time-driven, activity-based costing with observations and process mining, we trial a method for measuring care costs for large cohorts using electronic health record data. To support this method, we create activity and process maps for all relevant treatments: ovulation induction, intrauterine insemination, in vitro fertilisation (IVF), IVF with intracytoplasmic sperm injection and frozen embryo transfer after IVF. Our study design, by showing how different sources of data can be combined to enable cost and outcome measurements, can be of value to researchers and practitioners looking to measure costs for care paths or entire patient journeys in complex care settings.Ethics and disseminationThis study was approved by the ESHPM Research Ethics Review Committee (ETH122-0355) and the Reinier de Graaf Hospital (2022–032). Results will be disseminated through seminars, conferences and peer-reviewed publications.
Tolerability of bedtime diuretics: a prospective cohort analysis
Authors: Garrison Scott R , Kelmer Michael , Korownyk Tina , Kolber Michael R , Allan Gary Michael , Bakal Jeffrey , Singer Alexander , Katz Alan , Mcalister Finlay , Padwal Raj S , Lewanczuk Richard , Hill Michael D , McGrail Kimberlyn , O’Neill Braden , Greiver Michelle , Manca Donna P , Mangin Dee , Wong Sabrina T , Kirkwood Jessica E M , McCormack James P , Yeung Jack M S , Green Lee 
Published: June 2023

ObjectivesWe sought to validate, or refute, the common belief that bedtime diuretics are poorly tolerated due to nocturia.DesignPrespecified prospective cohort analysis embedded within the randomised BedMed trial, in which hypertensive participants are randomised to morning versus bedtime antihypertensive administration.Setting352 community family practices across 4 Canadian provinces between March 2017 and September 2020.Participants552 hypertensive patients (65.6 years old, 57.4% female) already established on a single once-daily morning antihypertensive and randomised to switch that antihypertensive to bedtime. Of these, 203 used diuretics (27.1% thiazide alone, 70.0% thiazide/non-diuretic combinations) and 349 used non-diuretics.InterventionSwitching the established antihypertensive from morning to bedtime, and comparing the experience of diuretic and non-diuretic users.Primary and secondary outcome measuresPrimary outcome: Adherence to bedtime allocation time at 6 months (defined as the willingness to continue with bedtime use, not an assessment of missed doses). Secondary 6-month outcomes: (1) nocturia considered to be a major burden and (2) increase in overnight urinations/week. All outcomes were self-reported and additionally collected at 6 weeks.ResultsAt 6 months: Adherence to bedtime allocation time was lower in diuretic users than non-diuretic users (77.3% vs 89.8%; difference 12.6%; 95% CI 5.8% to 19.8%; p<0.0001; NNH 8.0), and more diuretic users considered nocturia a major burden (15.6% vs 1.3%; difference 14.2%; 95% CI 8.9% to 20.6%; p<0.0001; NNH 7.0). Compared with baseline, diuretic users experienced 1.0 more overnight urinations/week (95% CI 0.0 to 1.75; p=0.01). Results did not differ between sexes.ConclusionsSwitching diuretics to bedtime did promote nocturia, but only 15.6% found nocturia a major burden. At 6 months, 77.3% of diuretic users were adherent to bedtime dosing. Bedtime diuretic use is viable for many hypertensive patients, should it ever become clinically indicated.Trial registration numberNCT02990663.
Self-harm among unaccompanied asylum seekers and refugee minors: protocol for a global systematic review of prevalence, methods and characteristics
Authors: Hedrick Kyli , Borschmann Rohan 
Published: June 2023

IntroductionAsylum seekers and refugees are at an elevated risk of self-harm, with younger age and traumatic experiences found to further increase such risk. Despite this, evidence regarding self-harm among unaccompanied asylum seekers and refugee minors has not been synthesised. As self-harm among minors is a risk factor for a range of adverse clinical and social outcomes, including suicide, such information may help to inform evidence-based prevention strategies among these vulnerable populations. This systematic review will synthesise findings from the literature regarding the prevalence, methods and characteristics of self-harm, including risk and protective factors, among unaccompanied asylum seekers and refugee minors internationally.Methods and analysisWe searched key electronic databases (PsycINFO, Scopus, PubMed and Ovid MEDLINE) and grey literature for relevant studies published in English from database inception to 10 February 2023. Our primary outcome is self-harm among unaccompanied asylum seekers and/or refugee minors. With the exception of single-case studies, clinical trials and case-control studies, we will include all types of study design that examine the prevalence of self-harm in unaccompanied asylum seekers and/or refugee minors. We will exclude dissertations, conference abstracts, letters, book chapters, editorials, study registrations, registered protocols and qualitative studies. Only studies reporting on participants aged <18 years will be eligible for inclusion. The Methodological Standard for Epidemiological Research Scale will be used to assess the quality of included studies. If there are sufficient studies and homogeneity between them, we will conduct meta-analyses to calculate pooled estimates of self-harm rates, as well as comparisons between subgroups of relevance. If the studies do not report sufficient data, or there is substantial heterogeneity, we will provide a narrative synthesis of the findings.Ethics and disseminationThis review is exempt from ethics approval. Our findings will be disseminated through peer-reviewed publications and conference presentations.PROSPERO registration numberCRD42021292709.
Protocol for a qualitative study exploring the lived experience of hearing loss and patient reported experience in the UK: the HeLP study
Authors: Pryce Helen , Smith Sian Karen , Burns-O'Connell Georgina , Shaw Rachel , Hussain Saira , Banks Jonathan , Hall Amanda , Knibb Rebecca , Greenwood Rosemary , Straus Jean 
Published: June 2023

IntroductionWorldwide, hearing loss is a significant public health issue and one of the most common chronic health conditions experienced by older adults. Hearing loss is associated with communication difficulties, social withdrawal, isolation and lower quality of life. Although hearing aid technology has improved significantly, the workload of managing hearing aids has increased. The aim of this qualitative study is to develop a novel theory of people’s lived experience of hearing loss across the lifespan.MethodsEligible participants will be young people and adults aged 16 years and above who have a hearing loss and carers/family members of people with a hearing loss. This study will use individual, in-depth face-to-face or online interviews. With participants’ permission, interviews will be audio-recorded and transcribed verbatim. A grounded theory approach to concurrent data gathering and analysis will develop grouped codes and categories and link these to provide a novel theory to describe the experience of hearing loss.Ethics and disseminationThe study was approved by the West of Scotland Research Ethics Service (approval date: 6 May 2022 ref: 22/WS/0057) and the Health Research Authority and Health and Care Research Wales Approval (approval date: 14 June 2022; IRAS project ID: 308816). The research will inform the development of a Patient Reported Experience Measure to improve the information and support given to patients. Findings will be disseminated through peer-reviewed articles and at academic conferences, as well as to our patient and public involvement groups, healthcare professionals, audiology services and local commissioners.