bluuebunny/crossref_metadata_2025_split huggingface dataset:
A seminatural approach towards restoration, classification, and pattern extraction from heritage Hindi poetry: A probabilistic case study with Dohā chanda
Authors: Naaz Komal , Singh Niraj Kumar 
Published: July 2023

Abstract
Indian literary heritage is vast and is of great importance; to explore it, one has to devote them in studying dialects (Khariboli, Haryanavi, Brajbhasha, Awadhi, Bhojpuri, Marwari, etc.) especially when old Hindi is under the lens of observation. Chanda are poetic compositions that have well-defined structures. Dohā is a kind of chanda which, in our work, has been explored using Kabir’s compositions as a case study. Kabir represents the cult of poets who relied on oral means for the propagation and consumption of poetry. The poems were communicated to the later generation through simple acts of recitation and hearing, leading to obvious mutation and multiple versions of the same compositions when documented later and hence needs restoration (at least metrically). Using the knowledge from the state-of-art models metadata generator, Text2Mātrā, and RPaGen and extending beyond them, this article is first of its kind to present Kabir’s dohā within the scope of restoration, metrical computation, and statistics. Starting with the restoration process, the proposed algorithms generate data that are subjected to suitable statistical models. These models highlight the trends in the dataset, which is helpful in realizing abstract patterns inside the textual data.
Isolated angioedema due to face mask and other cases of isolated angioedema
Authors: Aksakal Sengul 
Published: July 2023

Abstract
Isolated angioedema can be divided into two groups as mast cell–mediated angioedema and bradykinin-mediated angioedema according to the known mechanisms of occurrence. However, angioedema can also occur with mechanisms whose cause is unknown. Treatment varies according to the mechanism of angioedema formation. In this prospective study, we present the causes of 80 isolated angioedema cases admitted to our clinic during the pandemic period. We would like to emphasize the causes that we found in our cases but which are rare in the literature. For example: angioedema due to allergy to nickel in the mask used during the pandemic period, T cell–mediated angioedema, alpha adrenergic receptor blocker use, and patients diagnosed with collagen tissue disease presenting with angioedema as the first clinical finding.
Combining Wearable Technology and Telehealth Counseling for Rehabilitation After Lumbar Spine Surgery: Feasibility and Acceptability of a Physical Activity Intervention
Authors: Master Hiral , Coronado Rogelio A , Whitaker Sarah , Block Shannon , Vanston Susan W , Pennings Jacquelyn S , Gupta Rishabh , Robinette Payton , Stephens Byron , Abtahi Amir , Schwarz Jacob , Archer Kristin R 
Published: July 2023

Abstract

Objective
The purpose of this study was to examine the feasibility and acceptability of a wearable device and telehealth counseling physical activity intervention early after lumbar spine surgery.

Methods
Sixteen patients were randomized to an 8-session physical activity intervention or to usual postoperative care after surgery. The intervention included a wearable device (ie, Fitbit) and telehealth counseling by a licensed physical therapist. The feasibility of study procedures was assessed through recruitment, randomization, retention, and participation rates. Acceptability was assessed through a satisfaction survey and median within-participant change in objective physical activity (steps per day and time spent in moderate-to-vigorous physical activity [MVPA]) and patient-reported outcomes.

Results
Of 64 participants who were eligible, recruitment and randomization rates were 41 and 62%, respectively. Retention for objective physical activity and patient-reported outcomes was 94 and 100%, respectively, at 6-month follow-up. Seven (88%) participants in the intervention group completed all telehealth sessions, and 6 (75%) met step goals over the 8 sessions. All participants in the intervention group found the wearable device and telehealth counseling to be helpful and reported it much or somewhat more important than other postoperative services. Median within-participant change for steps per day improved from baseline (preoperative) to 6 months after surgery for both the intervention (1070) and usual care (679) groups, while MVPA only improved for the intervention group (2.2. minutes per day). Improvements in back and leg pain and disability were noted for both groups. No adverse events were reported in the study.

Conclusion
Combining wearable technology and telehealth counseling is a feasible approach to promote the physical activity during the early postoperative period after spine surgery. Future randomized controlled trials are needed to investigate the efficacy of leveraging wearables and telehealth during postoperative rehabilitation.

Impact
This study has implications for the clinical dissemination of physical activity strategies in the rehabilitation setting.
Pontine Waves Accompanied by Short Hippocampal Sharp Wave-Ripples During Non-rapid Eye Movement Sleep
Authors: Tsunematsu Tomomi , Matsumoto Sumire , Merkler Mirna , Sakata Shuzo 
Published: July 2023

Abstract
Ponto-geniculo-occipital or pontine (P) waves have long been recognized as an electrophysiological signature of rapid eye movement (REM) sleep. However, P-waves can be observed not just during REM sleep, but also during non-REM (NREM) sleep. Recent studies have uncovered that P-waves are functionally coupled with hippocampal sharp wave ripples (SWRs) during NREM sleep. However, it remains unclear to what extent P-waves during NREM sleep share their characteristics with P-waves during REM sleep and how the functional coupling to P-waves modulates SWRs. Here, we address these issues by performing multiple types of electrophysiological recordings and fiber photometry in both sexes of mice. P-waves during NREM sleep share their waveform shapes and local neural ensemble dynamics at a short (~100 milliseconds) timescale with their REM sleep counterparts. However, the dynamics of mesopontine cholinergic neurons are distinct at a longer (~10 seconds) timescale: although P-waves are accompanied by cholinergic transients, the cholinergic tone gradually reduces before P-wave genesis during NREM sleep. While P-waves are coupled to hippocampal theta rhythms during REM sleep, P-waves during NREM sleep are accompanied by a rapid reduction in hippocampal ripple power. SWRs coupled with P-waves are short-lived and hippocampal neural firing is also reduced after P-waves. These results demonstrate that P-waves are part of coordinated sleep-related activity by functionally coupling with hippocampal ensembles in a state-dependent manner.
Eye-mask and earplugs compared with sleep advice leaflet to improve night sleep duration in pregnancy: a randomized controlled trial
Authors: Gan Farah , Sooriappragasarao Muginrarao , Sulaiman Sofiah , Razali Nuguelis , Hong Jesrine Gek Shan , Tan Peng Chiong 
Published: July 2023

Abstract

Study Objectives
To evaluate at-home use of eye-mask and earplugs (EMEP) versus sleep hygiene advice leaflet (AL) on actigraphy-derived night sleep duration in sleep-deprived pregnant women.

Methods
A randomized controlled trial was conducted in the antenatal clinic of University Malaya Medical Centre from June 2021 to June 2022. Women at 34–36 weeks gestation with self-reported night sleep duration ≤6 hours were recruited. Participants wore an actigraphy device at night for seven consecutive nights (Observation/Baseline week). Only women whose actigraphy-derived night sleep duration was confirmed to be ≤360 minutes were randomized to use EMEP or AL. Actigraphy was continued for another week (Intervention week). Primary outcome was change in actigraphy-derived night sleep duration from observation to intervention week across trial arms. Secondary outcomes include participants’ sleep quality, labor, and neonatal outcome. Comparisons were by Student t-test, Mann–Whitney U test, and chi-square test.

Results
A total of 210 women were randomized: 105 each to EMEP and AL. The increase in night sleep duration over baseline was significantly longer with both EMEP (mean ± SD) 23 ± 41 minutes, p &lt; .001, and AL 10 ± 35 minutes, p = .007. Night sleep duration was longer by 12.9 (95% CI = 2.2 to 23.7) minutes, p = .019 with EMEP over AL. Sleep quality (Global Pittsburgh Sleep Quality Index score) was significantly improved with EMEP (mean ± SD) −2.0 ± 2.5, p &lt; .001, but not with AL −0.3 ± 2.2, p = .246. Labor and neonatal outcomes were not significantly different.

Conclusion
EMEP significantly lengthened night sleep duration in sleep-deprived women in late pregnancy and is superior to AL.

Clinical Trial Information
“Use of eye masks and earplugs compared with standard advice to improve sleep in pregnancy”. https://doi.org/10.1186/ISRCTN19061849. Registered with ISRCTN on 07 May 2021, trial identification number: ISRCTN19061849.
Psychological Distress after inpatient non-cardiac Surgery
Authors: Gandotra Sakshi , Daza Julian F. , Diep Calvin , Mitani Aya A. , Ladha Karim S. , Wijeysundera Duminda N. ,   on behalf of the METS Study Investigators
Published: July 2023

Objective:
Describe the incidence and natural progression of psychological distress after major surgery.

Summary Background:
The recovery process following surgery imposes physical and mental burdens that put patients at risk of psychological distress. Understanding the natural course of psychological distress after surgery is critical to supporting timely and tailored management of high-risk individuals.

Methods:
We conducted a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) multicentre cohort study (Canada, Australia, New Zealand, UK). METS recruited adult participants (≥40 y) undergoing elective inpatient non-cardiac surgery and followed them for one year. The primary outcome was the severity of psychological distress measured using the anxiety-depression item of EQ-5D-3L. We used cumulative link mixed models to characterize the time trajectory of psychological distress among relevant patient subgroups. We also explored potential predictors of severe and/or worsened psychological distress at one year using multivariable logistic regression models.

Results:
Of 1,546 participants, moderate-to-severe psychological distress was reported by 32.6% of participants before surgery, 27.3% at 30 days after surgery, and 26.2% at 1 year after surgery. Psychological distress appeared to improve over time among females (OR 0.80, 95% CI 0.65–0.95) and patients undergoing orthopedic procedures (OR 0.73, 95% CI 0.55–0.91), but not among males (OR 0.87, 95% CI 0.87–1.07) or patients undergoing non-orthopedic procedures (0.95, 95% CI 0.87–1.04). Among the average middle-aged adult, there were no time-related changes (OR 0.94, 97% CI 0.75–1.13) whereas the young-old (OR 0.89, 95% CI 0.79–0.99) and middle-old (OR 0.87, 95% CI 0.73–1.01) had small improvements. Predictors of severe and/or worsened psychological distress at one year were younger age, poor self-reported functional capacity, smoking history, and undergoing open surgery.

Conclusion:
One-third of adults experience moderate to severe psychological distress before major elective non-cardiac surgery. This distress tends to persist or worsen over time among select patient subgroups.
The impact of fentanyl on DUIDs and traffic fatalities: Blood and oral fluid data
Authors: Harper Curt E. , Mata Dani C. , Lee Dayong 
Published: July 2023

AbstractFentanyl has emerged as the most prolific drug in the ongoing opioid epidemic and has greatly impacted traffic safety in recent years. This study aimed to evaluate fentanyl prevalence and concentrations in blood and oral fluid in driving under the influence of drugs (DUID) cases in three different regions (i.e., Alabama, Orange County, CA, and Houston, TX) from 2017 to 2022. Furthermore, traffic fatalities were evaluated for Alabama and Orange County, CA. Fentanyl positivity in DUID and traffic fatalities increased for most years in this study. In Alabama, the prevalence of fentanyl DUID cases increased 4‐fold in 2022 compared to 2017. Orange County's increase from 2017 to 2022 was 14‐fold. In Houston, the increase was approximately 2‐fold from 2019 to 2022. The greatest increase for all laboratories coincided with the start of the COVID‐19 pandemic. In 2022, the median fentanyl DUID blood concentrations were 4.7, 11, and 4.7 ng/mL in Alabama, Orange County, and Houston, respectively. Most fentanyl cases were polydrug cases (≥90%). Methamphetamine, THC, and alprazolam were the most frequently detected drugs in combination with fentanyl. Alabama has collected oral fluid and blood in DUID cases since 2018. The detection of fentanyl in oral fluid was comparable to blood. However, 59% and 8.7% of fentanyl‐positive cases had concentrations of >20 ng/mL in oral fluid and blood, respectively. Therefore, oral fluid as an alternative or supplemental specimen to blood is an attractive approach for fentanyl in DUID cases. This study contributes to understanding recent fentanyl trends and their impact on traffic safety.
Anal cancer: a 20‐year retrospective study from Australia
Authors: Wong Jean , Allwright Maggie , Hruby George , Roberts Jennifer M. , Carr Andrew , Jin Fengyi , Gett Rohan , Meagher Alan P. , Hillman Richard 
Published: July 2023

AbstractBackgroundsAnal cancer is an uncommon condition, occurring at higher rates in specific subpopulations. Clinical experience is limited and substantial changes have recently occurred in our understanding of this condition. We, therefore, set out to characterize patients presenting with anal cancer and investigate whether there have been any changes over the past 20 years.MethodsRetrospective audit of cases identified from pathology and clinical databases during the period 1 January 2000 to 31 December 2019.ResultsTwo hundred and sixteen patients had anal squamous cell carcinomas, comprising 160 (74%) males and 56 (26%) females. Mean age at initial diagnosis was 55.1 ± 11.20 for males and 60.6 ± 15.18 for females (P = 0.02). At initial diagnosis, HIV‐positive cases were significantly younger than HIV negative cases (mean 52.2 ± 9.35 vs. 62.8 ± 11.61, P < 0.001); 46% of cases were classified as intra‐anal, 29% perianal and 25% both; 52% were > 2 cm at diagnosis. At presentation, intra‐anal cases were larger and more advanced than perianal cases (P = 0.049). Compared with the period 2000–2009, anal cancers presented more commonly in 2010–2019 (148 vs. 76), were more likely to occur in HIV‐negative people and to be diagnosed at a similar stage.ConclusionThe number of anal cancer cases almost doubled over the study period and people living with HIV presented 10 years younger than others. Perianal cases presented earlier than those originating in intra‐anal locations. Together with the large size at diagnosis, this suggests the potential value of screening, particularly for intra‐anal cancers in those at high risk.
The history of Danish neuroscience
Authors: Paulson Olaf B. , Schousboe Arne , Hultborn Hans 
Published: July 2023

AbstractThe history of Danish neuroscience starts with an account of impressive contributions made at the 17th century. Thomas Bartholin was the first Danish neuroscientist, and his disciple Nicolaus Steno became internationally one of the most prominent neuroscientists in this period. From the start, Danish neuroscience was linked to clinical disciplines. This continued in the 19th and first half of the 20th centuries with new initiatives linking basic neuroscience to clinical neurology and psychiatry in the same scientific environment. Subsequently, from the middle of the 20th century, basic neuroscience was developing rapidly within the preclinical university sector. Clinical neuroscience continued and was even reinforced during this period with important translational research and a close co‐operation between basic and clinical neuroscience. To distinguish ‘history’ from ‘present time’ is not easy, as many historical events continue in present time. Therefore, we decided to consider ‘History’ as new major scientific developments in Denmark, which were launched before the end of the 20th century. With this aim, scientists mentioned will have been born, with a few exceptions, no later than the early 1960s. However, we often refer to more recent publications in documenting the developments of initiatives launched before the end of the last century. In addition, several scientists have moved to Denmark after the beginning of the present century, and they certainly are contributing to the present status of Danish neuroscience—but, again, this is not the History of Danish neuroscience.
Gluten subfractions of wheat storage proteins are affected by high night temperature during grain formation
Authors: Parveen Shamima , Sharma Poornima , Kaushik Megha , Divte Pandurang R. , Mandal Pranab Kumar , Jain Neelu , Anand Anjali 
Published: July 2023

AbstractGluten (gliadin + glutenin) protein in wheat flour is affected by high temperature (day and/or night) resulting in undesirable consequences on dough quality. A study was conducted with early and late‐maturing wheat genotypes, to assess the spatial (superior‐ central and inferior‐ apical and basal spikelets) variation in the composition of gluten subfractions in the developing ear under high night temperature (HNT). We hypothesised that protein content in the superior and inferior grains may show a differential quantitative and qualitative response to HNT. HNT resulted in a significant increase in protein content which exhibited a strong (r = −0.44*) negative correlation with sedimentation volume (SV) that determines baking quality. The late‐maturity genotypes were more responsive to HNT with changes in ω‐5 and γ gliadin subfractions of both superior and inferior spikelets, though a consistent trend was not established. The proportion of high molecular weight (HMW) glutenins increased, whereas low molecular weight (LMW) glutenins reduced in most of the genotypes under HNT. Both HMW and LMW glutenins revealed significant positive (r = 0.43* and r = 0.81***, respectively) correlation with SV. The expression analysis of genes for gluten subfractions showed a significant decrease in transcript abundance of α, ω‐5, γ, HMW, and LMW fractions under HNT.
Families in quarantine: COVID‐19 pandemic effects on the work and home lives of women and their daughters
Authors: Coyle Emily F. , Fulcher Megan , Baker Konner , Fredrickson Craig N. 
Published: July 2023

AbstractThe onset of the COVID‐19 pandemic in March 2020 disrupted the lives of millions of US families, with rising unemployment and initial lockdowns forcing nationwide school and daycare closures. These abrupt changes impacted women in particular, shifting how families navigated roles. Even pre‐pandemic, US women were responsible for the majority of household labor and childcare, and daughters bore greater chore responsibility than sons. We surveyed 280 families early in the pandemic (Spring 2020) and another 199 families more than a year later (Summer 2021) about pre‐pandemic versus current work‐family conflict (WFC), division of labor and schooling, and children's daily activities. Early on, mothers reported increased WFC (especially family impacting work), mothers assumed primary responsibility for children's education at home, and daughters spent more time doing chores and educating siblings. One year in, WFC remained high but mother's stress was lower, parents reported working less from home, and children largely returned to face‐to‐face schooling. Yet, children, especially daughters, actually spent more time caring for siblings than early in the pandemic, though less time on chores overall. We conclude that policies that support families such as paid family leave and subsidized childcare are needed to right the gender inequalities exacerbated by the pandemic.
Cardiac resynchronization therapy for patients with heart failure and nonspecific intraventricular conduction delay
Authors: Cao Zezhong , Chen Xinmin , Su Lan , Hou Xiaofeng 
Published: July 2023

AbstractThe efficacy of cardiac resynchronization therapy (CRT) in heart failure patients with left bundle branch block (LBBB) is well established with Class I or IIa recommendation according to 2021 ESC Guidelines on cardiac pacing and CRT, whereas non‐LBBB morphology is less recommended. There is insufficient evidence that proves patients with NICD could benefit from CRT. As patients with NICD are characterized by heterogeneity, the effect of CRT on these patients is still controversial. Although the proportion of NICD in the population is lower than that of LBBB patients, it is still worth investigating the effects of CRT on patients with NICD in an era of His‐Purkinje conduction system pacing (HPCSP).
A qualitative study of school nurses’ moral distress related to COVID‐19
Authors: Baker Christina , Jones Jacqueline , Weiss Charlotte R. , Harpin Scott B. 
Published: July 2023

AbstractObjectiveTo understand school nurses' perceptions and experiences of moral distress related to COVID‐19 case management in the school systems.DesignA descriptive qualitative study guided by Braun and Clarke's reflexive thematic analysis.SampleTwelve school nurses practicing in Colorado from December 2021 to January 2022.MeasurementsSemi‐structured interviews about school nurses’ experiences of COVID‐19. Investigators utilized an iterative reflexive thematic analysis process engaging the participants' and researchers' subjective experiences.ResultsFour themes were created: (1) keeping kids and the community safe, (2) caught in the middle of the “tug of war” between health and politics, (3) distress amid an ocean of COVID‐19 uncertainty, and (4) visibility as a bright spot shining through the COVID‐19 cloud.ConclusionsTwo research questions examined school nurses’ experiences of moral distress and their role and scope of practice that affected their relationships in the educational and public health systems. The results of this study confirm the important role of school nurses and interprofessional case management in school environments in the fight against infectious diseases and pandemics. Building stronger relationships between school nurses and public health is imperative for future collaborative and cohesive public health responses to pandemics.
Total Loss of Feedwater Analysis of Pressurized Water Reactor Using RELAP5
Authors: Prošek Andrej 
Published: July 2023

Abstract
In Europe, the design extension conditions (DEC) were introduced after the Fukushima Dai-ichi accident as preferred method for giving due consideration to the complex sequences and severe accidents without including them in the design basis conditions. The objective of the study is to determine available elapsed time before core uncovery and needed DEC safety features for total loss of all feedwater (TLOFW) in a two-loop pressurized water reactor. RELAP5/MOD3.3 computer code has been used for calculations. The initiating event for TLOFW is multiple failures in which, in addition to the loss of main feedwater, the auxiliary feedwater is also lost. The scenarios without DEC safety features and the scenarios with DEC safety feature assumed have been simulated. The results showed that after TLOFW event initiation, it is very important to trip the reactor as soon as possible. In case of loss of offsite power, the reactor coolant pumps stop, and the reactor very quickly trips on low reactor coolant pump flow. When normal operation systems are assumed, the reactor trip occurs on low-low steam generator narrow level few tens of seconds after accident initiation, resulting in less time available before core uncovery occurence. The results for TLOFW scenarios with normal operation systems and DEC safety features assumed demonstrated that secondary side bleed and feed can prevent core uncovery in case when no operator actions are credited in the first 30 min of event. When primary side bleed and feed is used, less time is available for operator actions.