bluuebunny/crossref_metadata_2025_split huggingface dataset:
PROMIS Scores for Plantar Fasciitis Before and After Gastrocnemius Recession
Authors: Sanchez Thomas , Sankey Turner , Schick Sam , Arthur Rodney , Young Matt , Underwood Meghan , Harrelson Whitt , Shah Ashish 
Published: March 2023

Background: There has been an established relationship between increased loading on the Achilles tendon and tension on the plantar fascia. This supports the idea that either tight gastrocnemius and soleus muscles or contractures of the Achilles tendon are risk factors for plantar fasciitis. Gastrocnemius recession has gained popularity as a viable surgical intervention for cases of chronic plantar fasciitis due to isolated gastrocnemius contracture. To our knowledge, this is the first study to investigate Patient-Reported Outcome Measurement Information Systems (PROMIS) scores in patients with plantar fasciitis before and after gastrocnemius recession. Methods: The Electronic Medical Record was queried for medical record numbers associated with Current Procedural Terminology code 27687 (gastrocnemius recession). Our study included all patients with a preoperative diagnosis of chronic plantar fasciitis with treatment via isolated gastrocnemius recession with 1-year minimum follow-up. Forty-one patients were included in our study. Patient variables were collected via chart review. Preoperative and postoperative PROMIS scores were collected in the clinic. Results: We followed up 41 patients with a median age of 48 years (interquartile range [IQR] 38-55) and median body mass index of 29.02 (IQR 29.02-38.74) for 1 year post surgery. Preoperative and postoperative PROMIS scores improved for physical function from 39.3 to 44.5 ( P = .0005) and for pain interference from 62.8 to 56.5 ( P = .0001). PROMIS depression scores were not significantly different ( P = .6727). Visual analog scale (VAS) scores significantly decreased from 7.05 to 1.71 ( P < .0001). Conclusion: In this case series, we found the gastrocnemius recession to be an effective option for patients with refractory pain in plantar fasciitis. Our PROMIS and VAS data confirm this procedure’s utility and highlight its ability to significantly decrease pain and improve physical function in patients with chronic plantar fasciitis, although final median scores did not reach normative standards for the population, suggesting some residual pain and/or dysfunction was, on average, present. Based on the results of this study, the authors conclude that gastrocnemius recession is a reasonable treatment option for chronic plantar fasciitis patients who fail nonoperative management. Level of Evidence: Level III, retrospective cohort study.
Becoming Southern: 10 Autoethnographic Polaroids
Authors: Kavoori Anandam 
Published: March 2023

I call it “the great emptying.” This business of making and re-making of the self. The immigrant self, that is:   I hold a bucket in my hand    Piled high with memories     Of Delhi, India,     I begin Swirling,    Swinging it over head Holding in a deep-deep breath, Throwing it out, away, as far as I can     Back to where it belongs      The past I call it The Great Filling. This business of making and re-making of the self. The immigrant self, that is: I hold a bucket in my hand   Filling it with memories,    Of Athens and Sapelo     I begin swirling,   Swinging it over my head Holding in a deep deep breath   Pouring it all over me    Over My Place    My Deep South
Feasibility of Microwave Scissors-Based Off-Clamp Laparoscopic Partial Nephrectomy in a Porcine Model
Authors: Nguyen Ha Ngoc , Yamada Atsushi , Naka Shigeyuki , Mukaisho Ken-Ichi , Tani Tohru 
Published: March 2023

Objectives To assess the feasibility of off-clamp laparoscopic partial nephrectomy using microwave scissors. Methods We performed transperitoneal laparoscopic partial nephrectomy, without hilar clamping or renorrhaphy, using only microwave scissors for renal resection in a porcine model. For each kidney, 2 types of procedures were performed: a middle pole resection excising an area of 2-cm diameter and approximately 1-cm depth and a lower pole resection at the level of the lower polar line. The renal calyces exposed during renal resection were sealed and transected using microwave scissors. After 3 days of follow-up, the pigs were reoperated to inspect for postoperative complications. Euthanasia was performed to collect the remaining kidneys for histopathological examination. Results Ten procedures were successfully performed, without hilar clamping or suturing of the renal calyces and parenchyma, in 5 kidneys from 3 pigs. The median resecting time, blood loss, and lateral thermal injury were 23.2 min, 47.1 mL, and 6.8 mm in the middle pole resection, and were 15.1 min, 26.5 mL, and 6.9 mm in the lower pole resection, respectively. No complications were noted during reoperation, such as postoperative hemorrhage and major urine leakage. Extravasation occurred in 2 middle pole resections and 3 lower pole resections during retrograde pyelogram. Hematoxylin and eosin staining revealed thermal injury characterized by tissue microwave fixation in the near zone and acute coagulative necrosis in the intermediate zone. Conclusions Microwave scissors-based off-clamp laparoscopic partial nephrectomy is feasible in pigs and can be used for clinical applications.
Post-traumatic Stress Disorder as an Independent Risk Factor for Increased Opioid Use Following Carpal Tunnel Surgery
Authors: Hudock Nicholas L. , Kshir Sean A. , Taylor Kenneth F. 
Published: March 2023

Background: Carpal tunnel release (CTR) is one of the most common hand surgeries. Studies have highlighted a mental-physical connection to hand pathologies and psychological connections to postoperative pain burden. Post-traumatic stress disorder (PTSD) has been identified as a medical-psychological comorbidity like other mental health disorders such as generalized anxiety disorder (GAD). There remains a gap in the literature regarding PTSD as a comorbidity for hand surgeries, where there is this mental-physical connection. We hypothesize PTSD will be associated with increased risk of postoperative pain, evidenced by greater prevalence of opioid usage. Methods: The authors performed a retrospective analysis using the TriNetX Research Database. Patients who underwent elective CTR were identified within the database. Two groups were created and compared against individual controls: the first was identified based on the diagnosis of PTSD, and the second was identified based on the diagnosis of GAD. Cohorts were matched and opioid usage was compared postoperatively. Results: Patients with PTSD who underwent CTR were found to be at significantly increased risk of postoperative opioid use ( P = .033) and more likely to present to the emergency department (ED) ( P = .001). Patients with GAD were found to be significantly less likely to require postoperative opioids ( P = .040). Conclusions: We found patients with PTSD to be at increased risk of opioid use and more likely to present to ED following CTR. Patients with GAD were found to be at decreased risk of opioid use after CTR. Owing to the independent significant risks not found in GAD, further research of postoperative pain in patients with PTSD is needed.
Proximal right subclavian artery aneurysms: A case report and review of the literature
Authors: Cui Hong-jie , Wu Ying-feng 
Published: March 2023

Background Subclavian aneurysms are rare in clinic; right subclavian artery aneurysms (SAAs) are more common than left SAAs in clinical practice. Although the causes and methods of treating subclavian aneurysms have been studied, it is still unknown how they form naturally. Objective While describing the uncommon subclavian aneurysm, examine the pertinent literature to discuss its etiology and treatment outcomes, and offer some recommendations for this patient’s treatment plan. Methods In this case report, we describe a man patient who had a right subclavian proximal aneurysm that was discovered by accident. No clear clinical symptoms or signs were present in the patient. Upon admittance, an examination revealed an aneurysm in the vertebral artery but no peripheral embolization or compression symptoms. The patient refused operation, so we opted for follow-up instead. Result The patient took an ultrasound examination at our first follow-up appointment 3 months after discharge, and the results showed no thrombosis or appreciable aneurysm enlargement. Follow-up appointments for 6 months and a year have begun. Conclusion Follow-up is a good method to monitor the course of subclavian aneurysms without a clear indication for surgery when there is a clear operation mode and risk.
Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis
Authors: Hapfelmeier Alexander , On Begum Irmak , Mühlau Mark , Kirschke Jan S. , Berthele Achim , Gasperi Christiane , Mansmann Ulrich , Wuschek Alexander , Bussas Matthias , Boeker Martin , Bayas Antonios , Senel Makbule , Havla Joachim , Kowarik Markus C. , Kuhn Klaus , Gatz Ingrid , Spengler Helmut , Wiestler Benedikt , Grundl Lioba , Sepp Dominik , Hemmer Bernhard 
Published: March 2023

Background: Multiple sclerosis (MS) is a chronic neuroinflammatory disease affecting about 2.8 million people worldwide. Disease course after the most common diagnoses of relapsing-remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS) is highly variable and cannot be reliably predicted. This impairs early personalized treatment decisions. Objectives: The main objective of this study was to algorithmically support clinical decision-making regarding the options of early platform medication or no immediate treatment of patients with early RRMS and CIS. Design: Retrospective monocentric cohort study within the Data Integration for Future Medicine (DIFUTURE) Consortium. Methods: Multiple data sources of routine clinical, imaging and laboratory data derived from a large and deeply characterized cohort of patients with MS were integrated to conduct a retrospective study to create and internally validate a treatment decision score [Multiple Sclerosis Treatment Decision Score (MS-TDS)] through model-based random forests (RFs). The MS-TDS predicts the probability of no new or enlarging lesions in cerebral magnetic resonance images (cMRIs) between 6 and 24 months after the first cMRI. Results: Data from 65 predictors collected for 475 patients between 2008 and 2017 were included. No medication and platform medication were administered to 277 (58.3%) and 198 (41.7%) patients. The MS-TDS predicted individual outcomes with a cross-validated area under the receiver operating characteristics curve (AUROC) of 0.624. The respective RF prediction model provides patient-specific MS-TDS and probabilities of treatment success. The latter may increase by 5–20% for half of the patients if the treatment considered superior by the MS-TDS is used. Conclusion: Routine clinical data from multiple sources can be successfully integrated to build prediction models to support treatment decision-making. In this study, the resulting MS-TDS estimates individualized treatment success probabilities that can identify patients who benefit from early platform medication. External validation of the MS-TDS is required, and a prospective study is currently being conducted. In addition, the clinical relevance of the MS-TDS needs to be established.
Chemical Constituents From the Marine Microalgae Thraustochytrium pachydermum
Authors: Thuy Nguyen Thi Thu , Minh Hien Hoang Thi , Ha Nguyen Cam , Thom Le Thi , Hong Dang Diem , Thinh Nguyen Van , Dan Nguyen Trong , Hoi Nguyen Dang , Loan Vu Thi , Quang Hoang Duc , Hang Dan Thi Thuy , Kiem Phan Van , Dat Nguyen Tien , Nhiem Nguyen Xuan 
Published: March 2023

Objectives Isolation, structure determination, and antimicrobial activities evaluation of compounds from the methanol extract of the marine microalga Thraustochytrium pachydermum TSL10. Methods Using chromatographic methods to isolate compounds from the methanol extract of the T pachydermum. The chemical structures were elucidated by analyses of HR-ESI-MS and NMR spectral data. The antimicrobial activities of compounds were evaluated using the dilution turbidimetric broth method as the standard protocol published by the Clinical and Laboratory Standard Institute. Results One new sterol, (24 R)-ergosta-7,22-diene-3 β,5 α,9 α-triol (1), and 16 known compounds, ergosta-7,22-diene-3 β,5 α-diol (2), cerevisterol (3), (22 E,24 S)-5 α,6 α-epoxy-ergosta-8(9),22-diene-3 β,7 α-diol (4), ergosterol (5), 5 α,8 α-epidioxyergosta-6,22-diene-3 β-ol (6), linoleic acid (7), 4-((9 Z,12 Z)-octadeca-9,12-dienoyloxy)butanoic acid (8), 1-linoleoyl-sn-glycero-3-phosphocholine (9), cibotiglycerol (10), gingerglycolipid B (11), oleic acid (12), 4-((9Z)-octadec-9-enoyloxy)butanoic acid (13), (2 S)-1- O-(9 Z)-octadec-9-enoyl)-3- O-(6-sulfo-D-quinovopyranosyl)glycerol (14), 6′- O-linoleylsucrose (15), gingerglycolipid C (16), and ( S)-3-stearoyl- sn-glycerol (17) were identified from the marine microalga Thraustochytrium pachydermum TSL10. Sterols 1–6 were found to exhibit significant antimicrobial activities on Gram-( + ) bacteria ( Enterococcus faecalis ATCC29212 , Staphylococcus aureus ATCC25923, and Bacillus cereus ATCC14579) and the yeast ( Candida albicans ATCC10231) with MIC values ranging from 32 to 256 µg/mL. Conclusions The results suggested sterols 1–6 could be potential antimicrobial agents against Gram-( + ) bacteria.
The process of Transformative Learning in Dialog Café with Health Professionals and Citizens/Patients
Authors: Son Daisuke , Ishikawa Hirono , Yonekura Yuki , Nakayama Kazuhiro 
Published: March 2023

Introduction: Dialogue Café, which is an inclusive process that provides a platform for the exchange of ideas or perspectives on certain issues, is a suitable approach to facilitating mutual understanding between health professionals and citizens/patients. However, little is known about the effects of the Dialogue Café on participants in the context of health communication. Previous studies suggest that transformative learning occurs after dialogue. Objectives: This study aimed to clarify the process of the transformative learning process among participants of the Dialog Café and to evaluate whether their transformative learning would lead to an understanding of others’ perspectives. Methods: We conducted a psychometric analysis of a web-based questionnaire consisting of 72 items for participants of Dialog Café held from 2011 to 2013 in Tokyo and studied the relationships between various concepts using structural equation modeling (SEM). To evaluate the validity and reliability of concept measurement, we conducted an exploratory factor analysis and a confirmatory factor analysis. Results: The questionnaire response rate was 39.5% (141/357), of which 80 (56.7%) respondents were health professionals and 61 (43.3%) respondents were citizens/patients. The SEM analysis revealed that transformative learning occurred in both groups. The process of transformative learning consisted of 2 types; one process leading directly to “perspective transformation” and the other leading to “perspective transformation” via “critical self-reflection” and “disorienting dilemmas.” “Perspective transformation” was related to “understanding others” in both groups. Among health professionals, “perspective transformation” was related to “transformation of awareness toward patients/users.” Conclusion: Dialog Café can facilitate the process of transformative learning among participants, and transformative learning may lead to mutual understanding between health professionals and citizens/patients.
Lost in translation? A qualitative study of representations and management of chronic depression in general practice
Authors: Linder Audrey , Widmer Daniel , Fitoussi Claire , Gagnebin Lucile , de Roten Yves , Despland Jean-Nicolas , Ambresin Gilles 
Published: March 2023

Abstract
Background
GPs are on the front line for the identification and management of chronic depression but not much is known of their representations and management of chronic depression.

Objectives
To analyze GPs’ representations of chronic depression and to explore how they manage it.

Methods
Three focus groups were conducted with 22 French-speaking general practitioners in Switzerland. The focus groups were transcribed and coded with MaxQDA. A detailed content analysis was carried out and the results were synthesized into a conceptual map.

Results
GPs form representations of chronic depression at the intersection of expert and lay knowledge. When talking about patients suffering from chronic depression, GPs mention middle-aged women with complex psychosocial situations and somatic complaints. GPs’ management of chronic depression relies on the relationship with their patients, but also on taking care of them as a whole: psyche, body and social context. GPs often feel helpless and lonely when confronted with a patient with chronic depression. They insist on the importance of collaboration and supervision. As regards chronic depression management, GPs remain alone with patients suffering from complex biopsychosocial situations. In other situations, GPs seek the help of a psychiatrist, sometimes quickly, sometimes after a long approach. In each situation, GPs have to develop skills for translating patients’ complaints.

Conclusion
GPs endorse a role of interpreter, making the physical presentation of their patient complaints move towards a psychological appreciation. Our results call for a renewed interest in GPs’ role as interpreters and the means to achieve it.
How do respondents of primary care surveys compare to typical users of primary care? A comparison of two surveys
Authors: Cronin Shawna , Li Allanah , Bai Yu Qing , Ammi Mehdi , Hogg William , Wong Sabrina T. , Wodchis Walter P. 
Published: March 2023

Abstract
Background
Primary care surveys are a key source of evaluative data; understanding how survey respondents compare to the intended population is important to understand results in context. The objective of this study was to examine the physician and patient representativeness of two primary care surveys (TRANSFORMATION and QUALICOPC) that each used different sampling and recruitment techniques.

Methods
We linked the physician and patient participants of the two surveys to health administrative databases. Patients were compared to other patients visiting the practice on the same day and other randomly selected dates using sociodemographic data, chronic disease diagnosis, and health system utilization. Physicians were compared to other physicians in the same practice, and other physicians in the intended geographic area using sociodemographic and practice characteristics.

Results
Physician respondents of the TRANSFORMATION survey included more males compared to their practice groups, but not to other physicians in the area. TRANSFORMATION physicians cared for a larger roster of patients than other physicians in the area. Patient respondents of the QUALICOPC survey did not have meaningful differences from other patients who visit the practice. Patient respondents of the TRANSFORMATION survey resided in more rural areas, had less chronic disease, and had lower use of health services than other patients visiting the practice.

Conclusion
Differences in survey recruitment methods at the physician and patient level may help to explain some of the differences in representativeness. When conducting primary care surveys, investigators should consider diverse methods of ensuring representativeness to limit the potential for nonresponse bias.
Protocol for the SEHNeCa randomised clinical trial assesing Supervised Exercise for Head and Neck Cancer patients
Authors: Rodriguez-Arietaleanizbeaskoa M. , Mojas Ereño E , Arietaleanizbeaskoa MS , Grandes G. , Rodríguez Sánchez A , Urquijo V. , Hernando Alday I , Dublang M. , Angulo-Garay G. , Cacicedo J. ,   on behalf of the SEHNeCa group, Rodriguez-Arietaleanizbeaskoa Mario , Mojas Ereño Egoitz , Arietaleanizbeaskoa Maria S. , Grandes Gonzalo , Garcia-Alvarez Arturo , Coca Aitor , Mendizabal Nere , Hoyo Olga del , García-Escobedo Javier , Rodríguez Sánchez Ángel , Flores Barrenechea Lucía , Sánchez Rebeca , Urquijo Virginia , Barbier Herrero Luis , Díaz-Basterra Goiztidi , Gómez-Suarez Javier , Calles Romero Laura A , Iglesias-Hernandez Natalia C. , Hernando Alday Iñigo , Dublang Maddalen , Ramirez-Garcia Lina M. , Angulo-Garay Garazi , Dominguez-Martinez Silvia , Gil-Rey Erreka , Martinez-Aguirre Aitor , Gutierrez-Santamaria Borja , Cacicedo Jon 
Published: March 2023

Abstract
Objectives
To evaluate the effectiveness of an innovative supervised exercise programme to mitigate the loss of lean body mass, functional capacity and quality of life in people with head and neck cancer, as well as to identify the optimal moment to apply it, before or after radiotherapy treatment, compared with the prescription of a physical activity plan carried out autonomously.

Methods
Patients with squamous cell carcinoma of the head and neck (n = 144), treated with radiotherapy, will be randomly assigned to one of 3 comparison groups: pre-radiotherapy supervised exercise, post-radiotherapy supervised exercise and autonomous exercise, stratifying by human papillomavirus infection and previous surgery.
The exercise programme will be carried out in 36 sessions over 12 weeks, combining moderate and high intensity strength and aerobic exercises. The main outcome variable is the change in lean body mass at 6 months measured by bioimpedance, while secondary variables are functional capacity, symptoms, quality of life and adverse effects. Longitudinal generalised mixed models will be used for the analyses of the repeated measurements at 3, 6, and 12 months after baseline.

Conclusions
The pilot study supports the feasibility and safety of the project. However, as the programme progressed, attendance at the sessions decreased. Strategies will be necessary for increasing attendance, as well as involving the patient in their recovery and other incentives. Follow-up after treatment to assess acute/late toxicity will enable us to know the response to both the exercise programme and its adherence.

Trial registration
NCT04658706 Date and version identifier: March 1, 2023. Version 1.1
A novel pupilloplasty in crescent-shaped suturing pattern for coloboma and traumatic iris defects
Authors: Yao Xiaoming , Kang Qian , Qi Wei , Liu Yuan , Zhou Xiaoping , Wang Mingwu , Yang Yukun , Zhu Fengjiao , Cao Wenchao 
Published: March 2023

AbstractObjectivePurposeTo observe the safety and effect of the C-pupilloplasty for the treatment of iris coloboma and traumatic iris defects.MethodsA total of 21 cases (21 eyes) with iris coloboma or traumatic iris defects who underwent C-pupilloplasty (a single-pass three-throw technique) from Feb. 2016 to Mar. 2020 were analyzed retrospectively. Uncorrected visual acuity, refraction, corneal topographic keratometry and endothelial cell density were examined.ResultsAll the patients were successfully treated, and a central and round pupil was restored. The mean follow-up duration was 8.76 ± 3.58 months (ranging from 2 to 14 months). All patients had round or round-like pupils with a diameter less than or equal to 3 mm after the C-pupilloplasty. Very slightly endothelial loss, negligible symptoms such as glare, distortion, dizziness and photophobia were observed.ConclusionWe introduced a new technique of pupilloplasty (C-pupilloplasty) which could be a more straight forward and more effective treatment for iris coloboma and traumatic iris defect.