bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patients Satisfaction towards services provided in general surgical ward in King Faisal Hospital, Makkah, KSA.
Authors: AlSairafi Rani , Softa Sameer , Elfaki Elbagir , Simbawa Hatem , Ahmed Aisha 
Published: July 2023

Introduction: Patient satisfaction is often used as an imperative source of information to evaluate and develop a plan to improve health services quality1. Patient Satisfaction can be defined as fulfillment or meeting of expectation of a person from a service. The World Health Organization established the ultimate goal of preserving the best possible level of health for all people and providing high-quality care. This eventually could help in improving the surgical care so as to meet the satisfaction of the patients.
AIMS: To explore patients' perceptions regarding the quality of surgical care and satisfaction in the general surgical wards at King Faisal Hospital, Makkah, Saudi Arabia, throughout the stay in surgical ward, till the discharge time.
Methods: A cross-sectional descriptive study was conducted. A total of 182 surgical patients admitted to surgical ward and scheduled for surgery (elective and emergency) were included in our study, during the period of (February -July 2022). Data will be collected in this specially designed questionnaire and analyzed by excel sheet. All surgical in-patient interviewed on the day of discharge after surgery. focused on their experiences and satisfaction of all services rendered including operative care during their stay in surgical ward.
Results: Overall rate of the patients were satisfied (85.4%) with the service at admission counter and reception (85.7%) diet quality and service (87.4%) doctor-patient relationship, diet quality and services satisfied (72.5%), doctor-patient relations and professionalism (81.9%). However, (65.9%) of patient was dissatisfied with room preparation, cleanliness and quietness at the time of admission and during the stay in the ward and (37.4%) was dissatisfied with the behavior of nurses and cooperation.
Conclusion: Generally, there is high patient satisfaction general surgical wards services in King Faisal Hospital, Makkah, Saudi Arabia. health workers need to be more responsive by reducing waiting time for patient discharge note and keeping the room tidier and more comfortable for patients.
Проблемы кадрового обеспечения работы с детьми, имеющими расстройство аутистического спектра
Authors: Рымханова Айнагуль 
Published: July 2023

Цель статьи - изучение вопроса кадрового обеспечения коррекционно-педагогического процесса с детьми, имеющими расстройство аутистического спектра в Республике Казахстан. Имеющаяся практика показывает, что работодатели нуждаются в узкопрофильных специалистах, которые целенаправленно подготовлены для работа с детьми с РАС, владеющих навыками применения всех современных передовых зарубежных технологий, интенсивно внедряющихся в коррекционно-педагогическую практику. Подготовку специалистов для данной категорий детей целесообразно рассматривать в контексте профессиональной педагогической подготовки с соответствующей квалификацией, т.к. краткосрочные курсы повышения квалификации не обеспечат ожидаемых фундаментальных знаний и навыков на должном уровне. Учитывая специфику работы с детьми с расстройством аутистического спектра, которая заключается в индивидуальном подходе, в единстве психолого-педагогического и медицинского воздействия, задача вузов – обновить и расширить направления подготовки специальных педагогов с учетом типов образовательных организаций и характеров деятельности, согласно занимаемой должности в специальных (коррекционных) и общеобразовательных организациях с обязательным привлечениеме в реализацию образовательных программ практических психологов и медицинских работников, т.к. клиническая картина РАС требует выхода за рамки педагогической деятельности. В результате можно удовлетворить запрос родителей, работодателей, государства и общества на специалистов способных для: осуществления психологических, медицинских скрининговых тестов и диагностических мероприятий с детьми в раннем возрасте; анализа и оценка эффективности зарубежных коррекционных методик и технологий; апробации и внедрения результатов передовых мировых опытов с учетом адаптации и модификации; своевременного признания неэффективности тех или иных методик, которые не могут содействовать получению желаемых результатов по причине несоответствия условий применения или особенностей системы образования; исследования и разработки собственных методик; обучения и социализации детей с РАС; полноценной реализации прав детей с РАС на доступное и качественное образование.
Radiographic Changes Five Years After Treatment of Meniscal Tear and Osteoarthritic Changes
Authors: Katz Jeffrey N. , Collins Jamie E. , Brophy Robert H. , Cole Brian J. , Cox Charles L. , Guermazi Ali , Jones Morgan H. , Levy Bruce A. , MacFarlane Lindsey A. , Mandl Lisa A. , Marx Robert G. , Selzer Faith , Spindler Kurt P. , Wright Rick W. , Losina Elena , Chang Yuchiao 
Published: July 2023

ObjectiveMeniscal tear in persons aged ≥45 years is typically managed with physical therapy (PT), and arthroscopic partial meniscectomy (APM) is offered to those who do not respond. Prior studies suggest APM may be associated with greater progression of radiographic changes.MethodsWe assessed changes between baseline and 60 months in the Kellgren‐Lawrence (KL) grade and OARSI radiographic score (including subscores for joint space narrowing and osteophytes) in subjects aged 45–85 years enrolled into a seven‐center randomized trial comparing outcomes of APM with PT for meniscal tear, osteoarthritis changes, and knee pain. The primary analysis classified subjects according to treatment received. To balance APM and PT groups, we developed a propensity score and used inverse probability weighting (IPW). We imputed a 60‐month change in the OARSI score for subjects who underwent total knee replacement (TKR). In a sensitivity analysis, we classified subjects by randomization group.ResultsWe analyzed data from 142 subjects (100 APM, 42 PT). The mean ± SD weighted baseline OARSI radiographic score was 3.8 ± 3.5 in the APM group and 4.0 ± 4.9 in the PT group. OARSI scores increased by a mean of 4.1 (95% confidence interval [95% CI] 3.5–4.7) in the APM group and 2.4 (95% CI 1.7–3.2) in the PT group (P < 0.001) due to changes in the osteophyte component. We did not observe statistically significant differences in the KL grade. Sensitivity analyses yielded similar findings to the primary analysis.ConclusionSubjects treated with APM had greater progression in the OARSI score because of osteophyte progression but not in the KL grade. The clinical implications of these findings require investigation.
Scaling up of Growth, Fabrication, and Device Transfer Process for GaN‐based LEDs on H‐BN Templates to 6‐inch Sapphire Substrates
Authors: Vuong Phuong , Moudakir Tarik , Gujrati Rajat , Srivastava Ashutosh , Ottapilakkal Vishnu , Gautier Simon , Voss Paul L. , Sundaram Suresh , Salvestrini Jean Paul , Ougazzaden Abdallah 
Published: July 2023

AbstractThe growth of hexagonal boron nitride (h‐BN) and van der Waals (vdW) epitaxy of blue multi‐quantum well (MQW) GaN‐based LED heterostructures on 6‐inch sapphire substrates using metal‐organic chemical vapour deposition (MOCVD) is demonstrated. Challenges associated with the growth of large surface h‐BN and the subsequent vdW epitaxy of GaN‐based LED heterostructures are discussed. To overcome these challenges, the spatial uniformity is controlled of the growth temperature, optimizes the slope of temperature variations during the growth and cooling process, and manages the surface temperature during switching of gas flows. With these adaptations, high quality GaN‐based LED heterostructures are grown on h‐BN without any spontaneous delamination. The GaN‐based LED devices are then fabricated on a 6‐inch sapphire wafer, which are lifted off as a membrane and transferred to a flexible copper support. These GaN‐based LED devices emitt bright blue illumination with an electroluminescence peak at 437 nm. This scaling up of growth, lift‐off, and transfer can lead to the commercialization of GaN‐based LEDs on h‐BN template on 6‐inch sapphire substrates, with a process compatible with current modern equipment for the fabrication of LEDs and electronic devices.
Asymmetric Organocatalyzed Phospha‐Michael Addition for the Direct Synthesis of Biologically Active Chromenylphosphonates
Authors: Marqués‐López Eugenia , Sonsona Isaac G. , Garcés‐Marín Miryam , Gimeno M. Concepción , Herrera Raquel P. 
Published: July 2023

AbstractThe potential of phosphites as nucleophiles for the asymmetric synthesis of chiral chromene derivatives has been overlooked in the literature. Herein, we report a promising approach via asymmetric organocatalyzed phospha‐Michael addition to iminochromenes, using a bifunctional squaramide, which gives access to chromenylphosphonates, an interesting family of bioactive compounds. Our optimized protocol provides very good reactivity, affording yields of up to 95% and with chiral products exhibiting an enantiomeric excess of up to 98%.
Cyclic potentiodynamic passivation of 316L stainless steels of different crystallographic orientation produced by laser powder bed fusion: Towards the improvement of corrosion resistance
Authors: Gu Rong , Trisnanto Satria Robi , Brochu Mathieu , Omanovic Sasha 
Published: July 2023

AbstractThe influence of cyclic potentiodynamic passivation (CPP) of 316L stainless steels (SS) of different crystallographic orientation produced by laser powder bed fusion (LPBF) on the resulting general and pitting corrosion resistance is discussed. CPP was performed by cyclic voltammetry in aqueous 0.1 M NaNO3. Electrochemical tests including open circuit potential (OCP), electrochemical impedance spectroscopy (EIS), and linear potentiodynamic polarization were employed to evaluate the resulting corrosion properties of the surfaces in aqueous 3.5 wt.% NaCl. It was found that the CPP method enables the formation of a passive oxide surface film which significantly improved the materials' general and pitting corrosion resistance in comparison to the naturally‐formed passive film under the experimental conditions investigated. It was also found that the general corrosion resistance, for both the unmodified (naturally‐passivated) and CPP‐modified LPBF 316L samples, decreased in the order of {111} > {100} > polycrystalline > {110}. Although the CPP‐modified samples showed a significantly lower current in the passive region and higher pitting potentials, in comparison to the unmodified samples, their crystalline structure was found not to have any influence on the corresponding behaviours.
Challenges and lessons learned birthing during the COVID‐19 pandemic: A scoping review
Authors: Knox‐Kazimierczuk Francoise , Trinh Shannon , Odems Dorian , Shockley‐Smith Meredith 
Published: July 2023

AbstractBackground and AimsThe impact of the COVID‐19 pandemic on the healthcare system facilitated a change in policies to redress the consequences of increased demand and fear of disease transmission. Restrictive measures throughout the healthcare system limiting access to accompanying partners of birthing people in addition to fears of contracting COVID‐19, an increasing number of birthing people chose to have an out‐of‐hospital birth. Out‐of‐hospital births are not prevalent in the United States. However, in recent years the percentage of out‐of‐hospital births has been steadily increasing. COVID‐19 was a novel virus imposing a unique birthing situation for millions of women, complicated by lack of integration and varied policies in the U.S.MethodsTo better understand the challenges of birthing people during the pandemic a scoping review was conducted to explore the literature during the first wave of the pandemic related to out‐of‐hospital births. The approach for this review made use of the methodology manual published by the Joanna Briggs Institute for scoping reviews. All manner of publications (i.e. peer‐reviewed published articles, grey articles, conference proceedings, webinars, editorials, and textbook chapters) were included in the review.ResultsArticles retrieved from the database search yielded sixty‐three articles, after duplicate removal forty‐six records were available for screening. Articles were further excluded using the PRISMA process, yielding thirty‐one remaining records. From the thirty‐one records twelve themes emerged, which were collapsed into four meta‐themes.ConclusionThese meta‐themes focused on (a) advocacy, (b) homebirth infrastructure, (c) support networks, and (d) uncertainty during the pandemic. COVID‐19 has accelerated this movement to birthing at home and thought must be given to how the healthcare system is going to support and integrate this mode of birthing.
Potential economic impacts of foot‐and‐mouth disease in Brazil: A case study for Mato Grosso and Paraná
Authors: de Menezes Taís Cristina , Ferreira Filho Joaquim Bento de Souza , Countryman Amanda M. 
Published: July 2023

AbstractThis study investigates the economic effects of foot‐and‐mouth disease (FMD) by employing a regional, dynamic computable general equilibrium model in tandem with results from an epidemiological model to simulate an FMD outbreak in Brazil. Outbreaks located in Paraná and Mato Grosso negatively impact other states in Brazil, demonstrating a spillover effect of economic losses beyond the region directly affected by the disease. Results highlight the distributive effects of FMD outbreaks with most of the negative impacts falling predominantly on lower income workers and households. This study shows the importance of animal disease surveillance and control and provides estimates of the potential economywide effects of an FMD outbreak in Brazil.
Effect of infill pattern scaling on mechanical properties of FDM-printed PLA specimens
Authors: Birosz Márton Tamás , Andó Mátyás 
Published: July 2023

Abstract3D printing offers a significant advantage in the production of hollow parts through the use of infill patterns. However, these patterns are typically generated by slicer software with a primary focus on providing basic structural rigidity, while neglecting other important criteria. This paper presents a simplified infill scaling technique for fused deposition modeling (FDM) and evaluates its effectiveness through tensile tests. The research question addressed in this study is whether adjusting the size of the pattern can reduce print time while maintaining the same stiffness at a given infill ratio. The methodology involves analyzing the results obtained from the tensile tests. The findings reveal that the print time can be reduced to some extent by properly adjusting the size of the infill pattern. However, it is observed that the mechanical resistance is influenced by the layer formation process. In conclusion, this research contributes to understanding the relationship between infill scaling, print time reduction, and mechanical resistance in FDM 3D printing.
Co-incorporation of hydrotalcite and starch into biochar-based fertilizers for the synthesis of slow-release fertilizers with improved water retention
Authors: Lu Jiawei , Li Yongfu , Cai Yanjiang , Jiang Peikun , Yu Bing 
Published: July 2023

AbstractThe unsatisfactory nutrient slow-release and water-retention performance of traditional biochar-based compound fertilizers (BCF) severely limit their practical application. Herein, a new type of slow-release fertilizer with high water retention was fabricated via the incorporation of hydrotalcite and starch into BCF, named as HS-BCF. The water-retention and nutrient releasing performance of the prepared HS-BCF and related nutrient slow-release mechanism were investigated. The results showed that the incorporation of hydrotalcite and starch into BCF could increase the soil water-retention ratio by 5–10% points. The accumulated N, P, and K leaching amounts of HS-BCF in soil within 30 days were 49.4%, 13.3%, and 87.4% of BCF at most, respectively. Kinetic analysis indicated that the release of nutrients from HS-BCF was attributed to the coupling of the diffusion-controlled and relaxation-controlled mechanism. Moreover, hydrotalcite could bind with P in HS-BCF, contributing to the enhanced durability of P in HS-BCF. Finally, pot experiments showed that the N–P–K utilization efficiencies of HS-BCF were all higher than those of BCF due to a better synchronization between the nutrient release of HS-BCF and the uptake of tomato plants. Overall, the study may provide a promising strategy for simultaneously improving the water-retention and slow-release performance of traditional biochar-based fertilizers.
Graphical Abstract
Consumer Behavior as a Challenge and Opportunity for Circular Food Packaging—a Systematic Literature Review
Authors: Du Rietz Sabina , Kremel Anna 
Published: July 2023

AbstractThe food sector has been targeted as a potential site for the implementation of circular economy strategies. Food packaging, in particular, has caused concern due to its high production volume, short usage time, and problems related to waste management and littering. Circular economy strategies could potentially address these concerns if there is consumer acceptance and participation in circular systems. The present review seeks to inform future studies of the need for further research in this area by reviewing current knowledge of consumer behavior in relation to circular food packaging. When doing so, the study finds that studies have primarily focused on recycling, foremost in the European and American setting. However, less is known about consumers and circular packaging in developing countries. While reuse strategies were more prevalent in studies from the 1970–1980s, the review finds that such initiatives are yet again researched, which is promising given their generally favorable environmental footprint.
Apoplastic barriers of Populus × canescens roots in reaction to different cultivation conditions and abiotic stress treatments
Authors: Grünhofer Paul , Heimerich Ines , Herzig Lena , Pohl Svenja , Schreiber Lukas 
Published: July 2023

AbstractPopulus is an important tree genus frequently cultivated for economical purposes. However, the high sensitivity of poplars towards water deficit, drought, and salt accumulation significantly affects plant productivity and limits biomass yield. Various cultivation and abiotic stress conditions have been described to significantly induce the formation of apoplastic barriers (Casparian bands and suberin lamellae) in roots of different monocotyledonous crop species. Thus, this study aimed to investigate to which degree the roots of the dicotyledonous gray poplar (Populus × canescens) react to a set of selected cultivation conditions (hydroponics, aeroponics, or soil) and abiotic stress treatments (abscisic acid, oxygen deficiency) because a differing stress response could potentially help in explaining the observed higher stress susceptibility. The apoplastic barriers of poplar roots cultivated in different environments were analyzed by means of histochemistry and gas chromatography and compared to the available literature on monocotyledonous crop species. Overall, dicotyledonous poplar roots showed only a remarkably low induction or enhancement of apoplastic barriers in response to the different cultivation conditions and abiotic stress treatments. The genetic optimization (e.g., overexpression of biosynthesis key genes) of the apoplastic barrier development in poplar roots might result in more stress-tolerant cultivars in the future.
STAG2 inactivation reprograms glutamine metabolism of BRAF-mutant thyroid cancer cells
Authors: Li Xinru , Liu Yan , Liu Juan , Qiang Wei , Ma Jingjing , Xie Jingyi , Chen Pu , Wang Yubo , Hou Peng , Ji Meiju 
Published: July 2023

AbstractSTAG2, an important subunit in cohesion complex, is involved in the segregation of chromosomes during the late mitosis and the formation of sister chromatids. Mutational inactivation of STAG2 is a major cause of the resistance of BRAF-mutant melanomas to BRAF/MEK inhibitors. In the present study, we found that STAG2 was frequently down-regulated in thyroid cancers compared with control subjects. By a series of in vitro and in vivo studies, we demonstrated that STAG2 knockdown virtually had no effect on malignant phenotypes of BRAF-mutant thyroid cancer cells such as cell proliferation, colony formation and tumorigenic ability in nude mice compared with the control. In addition, unlike melanoma, STAG2 knockdown also did not affect the sensitivity of these cells to MEK inhibitor. However, we surprisingly found that STAG2-knockdown cells exhibited more sensitive to glutamine deprivation or glutaminase inhibitor BPTES compared with control cells. Mechanistically, knocking down STAG2 in BRAF-mutant thyroid cancer cells decreases the protein stability of c-Myc via the ERK/AKT/GSK3β feedback pathway, thereby impairing glutamine metabolism of thyroid cancer cells by down-regulating its downstream targets such as SCL1A5, GLS and GLS2. Our data, taken together, demonstrate that STAG2 inactivation reprograms glutamine metabolism of BRAF-mutant thyroid cancer cells, thereby improving their cellular response to glutaminase inhibitor. This study will provide a potential therapeutic strategy for BRAF-mutant thyroid cancers.
Stem cell-derived intestinal organoids: a novel modality for IBD
Authors: Tian Cheng-mei , Yang Mei-feng , Xu Hao-ming , Zhu Min-zheng , Yue Ning-Ning , Zhang Yuan , Shi Rui-yue , Yao Jun , Wang Li-sheng , Liang Yu-jie , Li De-feng 
Published: July 2023

AbstractThe organoids represent one of the greatest revolutions in the biomedical field in the past decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly similar to that of the tissue and organ. Using the regeneration ability of stem cells, a 3D organ-like structure called intestinal organoids is established, which can mimic the characteristics of real intestinal organs, including morphology, function, and personalized response to specific stimuli. Here, we discuss current stem cell-based organ-like 3D intestinal models, including understanding the molecular pathophysiology, high-throughput screening drugs, drug efficacy testing, toxicological evaluation, and organ-based regeneration of inflammatory bowel disease (IBD). We summarize the advances and limitations of the state-of-the-art reconstruction platforms for intestinal organoids. The challenges, advantages, and prospects of intestinal organs as an in vitro model system for precision medicine are also discussed.