bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single-operator left atrial appendage occlusion utilizing conscious sedation, transoesophageal echocardiography, lack of outpatient pre-imaging, and same-day expedited discharge: a feasibility case series
Authors: Golzarian Hafez , Pasley Benjamin A , Shah Sidra R , Thiel Arielle M , Hempfling Gerri L , Otto Michael , Otto Todd , Patel Sandeep M 
Published: July 2023

Abstract

Background
Contemporary procedural guidelines for percutaneous left atrial appendage occlusions (LAAO) with the WATCHMAN device often require the utilization of pre-screening imaging, general anaesthesia, intubation, a dedicated intra-procedural echocardiographer, and overnight observation. For these reasons, LAAO with the WATCHMAN is not economically feasible for many hospital systems. Thus, we sought to evaluate a newstrategy for implantation that may provide a more minimalistic and less cumbersome approach to LAAO.

Case summary
We describe five cases utilizing single-operator left atrial appendage occlusion utilizing conscious sedation, transoesophageal echocardiography, lack of outpatient pre-imaging, and same-day expedited discharge (SOLO-CLOSE)—a novel single-operator procedural strategy for LAAO that safely foregoes the aforementioned procedural requirements and allows for same-day early discharge. All five patients were observed according to our newly devised SOLO-CLOSE protocol and were safely discharged home the same day. Follow-up transoesophageal echocardiography (TEE) at 45 days and 1 year revealed well-seated and well-anchored devices with no leaks (&lt;5 mm) or device-related thrombi.

Discussion
The SOLO-CLOSE series is the first ever documented WATCHMAN strategy that utilizes a single-operator, TEE-guided, nurse-driven conscious sedation protocol that defers pre-screening imaging and allows for same-day discharge. The versatility of this technique allows proceduralists to comfortably achieve successful LAAO despite a wide range of risk profiles. This single-operator technique has potential to become a widely accepted universal approach for non-pharmacological cardioembolic stroke prophylaxis due to its efficacy, safety, simplicity, and presumable cost-effectiveness.
The built environment and cardiovascular disease: an umbrella review and meta-meta-analysis
Authors: Liu Mingwei , Meijer Paul , Lam Thao Minh , Timmermans Erik J , Grobbee Diederick E , Beulens Joline W J , Vaartjes Ilonca , Lakerveld Jeroen 
Published: July 2023

Abstract

Aims
To provide a comprehensive overview of the current evidence on objectively measured neighbourhood built environment exposures in relation to cardiovascular disease (CVD) events in adults.

Methods and results
We searched seven databases for systematic reviews on associations between objectively measured long-term built environmental exposures, covering at least one domain (i.e. outdoor air pollution, food environment, physical activity environment like greenspace and walkability, urbanization, light pollution, residential noise, and ambient temperature), and CVD events in adults. Two authors extracted summary data and assessed the risk of bias independently. Robustness of evidence was rated based on statistical heterogeneity, small-study effect, and excess significance bias. Meta-meta-analyses were conducted to combine the meta-analysis results from reviews with comparable exposure and outcome within each domain. From the 3304 initial hits, 51 systematic reviews were included, covering 5 domains and including 179 pooled estimates. There was strong evidence of the associations between increased air pollutants (especially PM2.5 exposure) and increased residential noise with greater risk of CVD. Highly suggestive evidence was found for an association between increased ambient temperature and greater risk of CVD. Systematic reviews on physical activity environment, food environment, light pollution, and urbanization in relation to CVD were scarce or lacking.

Conclusion
Air pollutants, increased noise levels, temperature, and greenspace were associated with CVD outcomes. Standardizing design and exposure assessments may foster the synthesis of evidence. Other crucial research gaps concern the lack of prospective study designs and lack of evidence from low-to-middle-income countries (LMICs).

Registration
PROSPERO: CRD42021246580
Association of Hyperlipidemia With Perioperative Complications in Posterior Cervical Spine Fusion
Authors: Okada Rintaro , Son Seung Min , Fresquez Zoe , Formanek Blake , Mertz Kevin , Buser Zorica , Wang Jeffrey C. 
Published: July 2023

Study Design:
A retrospective database study.

Objectives:
The purpose of the current study was to investigate the impact of hyperlipidemia (HLD) on the incidence of perioperative complications associated with posterior cervical spine fusion (PCF).

Background:
HLD is a very common disease that leads to atherosclerosis. Therefore, it can cause fatal diseases as well as lifestyle-related diseases. The possible impact of HLD on outcomes after PCF has not yet been investigated.

Methods:
Patients with cervical degeneration underwent initial PCF from 2010 through the third quarter of 2020 using the MSpine subset of the PearlDiver Patient Record Database. The incidence of perioperative complications was queried using relevant ICD-9, 10, and CPT codes. χ2 analysis was performed in age-, sex-, and Charlson Comorbidity Index (CCI)-matched populations to compare between non-HLD and HLD patients in each single-level and multilevel PCF.

Results:
Through propensity score matching, 1600 patients each in the HLD and non-HLD groups were analyzed in the single-level PCF, 6855 patients were analyzed in the multilevel PCF were analyzed. The comorbidity of HLD significantly decreased the incidence of respiratory failure in single-level PCF (OR=0.58, P<0.01). In the multilevel PCF, the presence of HLD increased the incidence of cervicalgia (OR=1.26, P=0.030). On the contrary, the incident of spinal cord injury (OR=0.72, P<0.01), dysphagia (OR=0.81, P=0.023), respiratory failure (OR=0.85, P=0.030), pneumonia (OR=0.70, P=0.045), neurological bladder (OR=0.84, P=0.041), and urinary tract infection (OR=0.85, P=0.021) in the HLD group were significantly lower than those in non-HLD group.

Conclusions:
In the current study, the presence of HLD significantly increased the incidence of postoperative cervicalgia in multilevel PCF. On the other hand, the incidence of some complications was significantly decreased with HLD. Further studies are needed taking into account other factors such as the treatment of HLD, its efficacy, and intraoperative events.

Level of Evidence:
Level III.
Aortic stenosis is independently associated with male gender, obesity renal failure, COPD, Caucasians and numerous inflammatory diseases in addition to known cardiovascular risk factors
Authors: Movahed Mohammad Reza , Timmerman Brandon , Hashemzadeh Mehrtash 
Published: July 2023

AbstractBackgroundAortic valve stenosis is associated with age, rheumatic fever, and bicuspid aortic valve but its association with other comorbidities such as inflammatory disease and race is less known. The purpose of this study was to investigate any association between aortic stenosis and many comorbidities.MethodWe utilized the large Nationwide Inpatient Sample database to evaluate any association between aortic stenosis and risk factors. We performed uni- and multivariate analyses adjusting for comorbid conditions.ResultsData were extracted from the first available database that used ICD-10 codes specifically coding for aortic stenosis alone, spanning from 2016 to 2020. Data included 112,982,565 patients. A total of 2,322,649 had aortic stenosis, with the remaining 110,659,916 patients serving as controls. We found a strong and independent significant association between aortic stenosis and coronary artery disease (OR: 2.11, CI 2.09 - 2.13, P < 0.001), smoking (OR: 1.08, CI 1.07 - 1.08, P < 0.001), diabetes mellitus (OR: 1.15, CI 1.14 - 1.16, P < 0.001), hypertension (OR: 1.41, CI 1.4 - 1.43, P < 0.001), hyperlipidemia (OR: 1.31, CI 1.3 - 1.32, P < 0.001), renal disease (OR: 1.3, CI 1.29 - 1.31, P < 0.001), chronic obstructive lung disease (COPD) (OR: 1.05, CI 1.04 - 1.05, P < 0.001), obesity (OR: 1.3, CI 1.29 -1.32, P < 0.001), rheumatoid arthritis (OR: 1.13, CI 1.11 - 1.15, P <0.001), scleroderma (OR: 1.93, CI 1.79 - 2.09, P <0.001), systemic connective tissue disease (OR: 1.24, CI 1.2 - 1.27, P <0.001), polyarteritis nodosa (OR: 1.5, CI 1.24 -1.81, P <0.001), and Raynauds syndrome (OR: 1.16, CI 1.09 - 1.24, P <0.001), in addition to known factors such as age, male gender and bicuspid aortic valve.ConclusionUsing a very large database, we found many new associations for presence of aortic valve stenosis including race, renal disease, several inflammatory diseases, COPD, and obesity in addition to many other known cardiovascular risk factors.
Examining the transition to adulthood in autism spectrum disorder: examining the perspectives of autistic individuals, caregivers and service providers
Authors: Nicholas David B. , Jubenville-Wood Theresa , Zulla Rosslynn T. , Lowe Katelyn , Zwaigenbaum Lonnie 
Published: July 2023

Purpose
The purpose of this study is to examine how the search for transitional services has been characterized as a challenging experience for autistic youth and their families. Transitional services are reported to be inconsistent and do not address the range of needs that autistic individuals have.

Design/methodology/approach
In this study, qualitative interviews were conducted with autistic individuals (n = 31), their parents/caregivers (n = 23) and transition-based service providers (n = 10).

Findings
Findings invite capacity building across sectors, including working with both the autistic individual and their caregiver, and ensuring targeted services commensurate with individual needs related to autism and ancillary challenges. Implications and recommendations for service and system advancement are offered.

Practical implications
Current services were reportedly insufficient in meeting the needs of autistic individuals as they transitioned into adulthood. Service areas needing to be bolstered include daily life, community engagement and employment. Capacity building and enhanced training are required. Information and communication strategies require advancement.

Social implications
A more responsive system is required, which involves support from many societal sectors (e.g. health, mental health, advanced education, social services, industry, housing and justice) over the lifespan. Policy adjustments and organizational mandates need to be reviewed to better consider the needs of transitioning autistic youth and allocate resources accordingly. Partnerships across stakeholder groups are needed.

Originality/value
This study provides details on a known but not well understood issue of transition to adulthood for autistic adults. This study is unique in providing first-hand data from transitioning autistic adults, with corroborating data from families and service providers.
Time to look forward: advocating future orientation in business network research
Authors: Halinen Aino , Nordberg-Davies Sini , Möller Kristian 
Published: July 2023

Purpose
Future is rarely explicitly addressed or problematized in business network research. This study aims to examine the possibilities of developing a business actor’s future orientation to network studies and imports ideas and concepts from futures research to support the development.

Design/methodology/approach
The study is conceptual and interdisciplinary. The authors critically analyze how extant studies grounded in the sensemaking view and process research approach integrate future time and how theoretical myopia hinders the adoption of a future orientation.

Findings
The prevailing future perspective is restricted to managers’ perceptions and actions at present, ignoring the anticipation and exploration of alternative longer-term futures. Future time is generally conceived as embedded in managers’ cognitive processes or is seen as part of the ongoing interaction, where the time horizon to the future is not noticed or is at best short.

Research limitations/implications
To enable a forward-looking perspective, researchers should move the focus from expectation building in business interaction to purposeful preparation of alternative future(s) and from the view of seeing future as enacted in the present to envisioning of both near-term and more distant futures.

Practical implications
This study addresses the growing need of business actors to anticipate future developments in the rapidly changing market conditions and to innovate and change business practices to save the planet for future generations.

Originality/value
This study elaborates on actors’ future orientation to business markets and networks, proposes the integration of network research concepts with concepts from futures studies and poses new types of research questions for future research.
Reflectance confocal microscopy as a non‐invasive imaging tool in vulvar high‐grade squamous intraepithelial lesions and lichen sclerosus: A descriptive morphological study in patients and healthy volunteers
Authors: Huisman Bertine W. , Pagan Lisa , Ulrich Martina , Rissmann Robert , Damman Jeffrey , Piek Jurgen M. J. , Niemeyer‐van der Kolk Tessa , van Poelgeest Mariette I. E. 
Published: July 2023

AbstractIncorrect and delayed diagnosis of vulvar high‐grade squamous intraepithelial neoplasia (vHSIL) and lichen sclerosus (LS) increases malignant progression risks and negatively impacts prognosis and quality of life. There is a need to improve diagnosis and monitoring. Reflectance confocal microscopy is a non‐invasive imaging tool that visualizes skin structures at cellular resolution. The objectives were to explore feasibility and patient acceptability of vulvar RCM imaging and to identify RCM characteristics that are discriminative for vulvar HSIL and LS. This was a prospective, cross‐sectional, observational clinical trial in patients with vHSIL and LS compared to healthy volunteers. RCM images and vulvar tissue samples were obtained. Five (5) patients with vHSIL, 10 patients with LS and 10 healthy volunteers were enrolled. In total, 100 image series of vulvar skin were obtained, including lesional and nonlesional sites. The RCM technique was considered acceptable for application by patients and healthy controls. Healthy vulvar skin was characterized by a homogenous, normal honeycomb patterned epidermis and a clear epidermal‐dermal junctions. Vulvar HSIL and LS displayed an atypical honeycomb pattern of the epidermis and lymphocytic influx with presence of melanophages. Distinct features specifically observed in LS included the presence of hyalinised vessels and sclerotic areas in the dermis. RCM is a non‐invasive imaging technique that is feasible and clinically acceptable to apply on vulvar skin, both in patients with premalignant lesions and healthy controls. Recognition and validation of disease‐specific characteristics could make reflectance confocal microscopy a clinical tool to non‐invasively aid identification of vulvar premalignancies.
Teaching relationship science: Continuity and change in the craft
Authors: Verette‐Lindenbaum Julie , Bartolic Silvia K. , Miller Rowland S. 
Published: July 2023

AbstractRelationship science is a dynamic, flourishing enterprise, with numerous discoveries and new lines of inquiry evident in recent changes in its textbooks and the teaching activities invented by its instructors. To survey changes and challenges in the teaching of courses that introduce students to relationship science—and to pursue “news instructors can use”—we surveyed 135 instructors of relationships courses regarding their teaching tactics and experiences. Guided by their responses and suggestions for further inquiry, we also examined the changes in textbooks on which they rely and reviewed teaching activities created to assist them with their teaching over the last 20 years. At present, some topics are nearly universal components of relationships courses but idiosyncrasy exists, particularly with regard to new topics—such as coverage of technology, intersectionality, or consensual nonmonogamy—that instructors plan to include in revisions of their courses. Suggestions for both new and experienced instructors are provided.
Treatment alternatives for the rehabilitation of the posterior edentulous maxilla
Authors: Avila‐Ortiz Gustavo , Vegh Dániel , Mukaddam Khaled , Galindo‐Moreno Pablo , Pjetursson Bjarni , Payer Michael 
Published: July 2023

AbstractRehabilitation of the edentulous maxilla with implant‐supported fixed dental prostheses can represent a significant clinical challenge due to limited bone availability and surgical access, among other factors. This review addresses several treatment options to replace missing teeth in posterior maxillary segments, namely the placement of standard implants in conjunction with maxillary sinus floor augmentation, short implants, tilted implants, and distal cantilever extensions. Pertinent technical information and a concise summary of relevant evidence on the reported outcomes of these different therapeutic approaches are presented, along with a set of clinical guidelines to facilitate decision‐making processes and optimize the outcomes of therapy.
Sensitivity of a Hymenoptera serological immunoglobulin (Ig)E assay for the diagnosis of venom hypersensitivity in dogs
Authors: Chan Hilary H. , Burrows Amanda K. , Hosgood Giselle , Ghubash Rudayna 
Published: July 2023

AbstractBackgroundHymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom hypersensitivity. The utility of venom allergen‐specific sIgE has not yet been evaluated for this purpose in dogs.ObjectivesThe objective of the study was to investigate the sensitivity (sn), specificity (sp) and positive predictive value (PPV) of honey bee and paper wasp serological titres using a commercially available sIgE assay [VARL (Veterinary Allergen Reference Laboratory) Liquid Gold] against clinical history for a diagnosis of Hymenoptera hypersensitivity in dogs.Materials and MethodsHoneybee and paper wasp IgE serum titres were measured in 15 client‐owned dogs with a diagnosis of Hymenoptera venom hypersensitivity based on a history of anaphylaxis, owner observation of Hymenoptera, and positive IDT to bee and/or wasp; and in 10 client‐owned dogs with no known history of anaphylaxis or Hymenoptera exposure and a negative IDT to bee and wasp.ResultsAnalysis of receiver operating characteristic (ROC) curves demonstrate that a VARL score cut‐off of one of six for honeybee yields Sn, Sp and PPV of 40%, 60% and 60%, respectively, and two of six for wasp yields Sn, Sp and PPV of 25%, 78% and 60%, respectively.Conclusions and Clinical RelevanceOwing to the poor sensitivity and PPV of sIgE assays for both bee and wasp hypersensitivity in dogs with known envenomation and anaphylaxis, the use of sIgE cannot be recommended as a tool for venom identification.
Effects of Resistance Training of Upper Limb and Trunk Muscles on Soccer Instep Kick Kinematics
Authors: de Assis Miguel Arcanjo , Santos Thiago Ribeiro Teles , Fonseca Sergio Teixeira , de Andrade André Gustavo Pereira , Araújo Priscila Albuquerque , de Souza Thales Rezende , Resende Renan Alves , Ocarino Juliana Melo 
Published: July 2023

The upper body and trunk muscles are crucial to perform soccer kicks. Resistance training targeting these muscles may modify the pattern adopted during kicking. This study aimed to investigate the effect of resistance training of the arm and anterior trunk muscles on instep kicking kinematics. Twenty-six male participants were randomly allocated into a training group or control group. The training group underwent resistance training of arm and trunk muscles and practiced the instep kick for 8 weeks. The control group only practiced kicking during the same period. The trunk, hip, and knee kinematics were assessed during the instep kick before and after the intervention. Kinematics were analyzed according to their data distribution with statistical parametric or nonparametric mapping. The effect of the training on the 1-repetition maximum test was analyzed using a repeated-measures multivariate analysis of variance. The training group showed greater hip extension after the training during the backswing phase (Hedge g effect size of 0.316–0.321) and increased 1-repetition maximum for all exercises. There were no other differences. The present study documented the nonlocal effect of strengthening training in which arm and trunk muscle training resulted in changes in hip kinematics during the backswing phase of the instep kick.
Speech Segmentation and Cross-Situational Word Learning in Parallel
Authors: Dal Ben Rodrigo , Prequero Isabella Toselli , Souza Débora de Hollanda , Hay Jessica F. 
Published: July 2023

Abstract
Language learners track conditional probabilities to find words in continuous speech and to map words and objects across ambiguous contexts. It remains unclear, however, whether learners can leverage the structure of the linguistic input to do both tasks at the same time. To explore this question, we combined speech segmentation and cross-situational word learning into a single task. In Experiment 1, when adults (N = 60) simultaneously segmented continuous speech and mapped the newly segmented words to objects, they demonstrated better performance than when either task was performed alone. However, when the speech stream had conflicting statistics, participants were able to correctly map words to objects, but were at chance level on speech segmentation. In Experiment 2, we used a more sensitive speech segmentation measure to find that adults (N = 35), exposed to the same conflicting speech stream, correctly identified non-words as such, but were still unable to discriminate between words and part-words. Again, mapping was above chance. Our study suggests that learners can track multiple sources of statistical information to find and map words to objects in noisy environments. It also prompts questions on how to effectively measure the knowledge arising from these learning experiences.
Dogs Bark, the Carnival Moves On… Revisiting Zygmunt Bauman, Modernity and the Holocaust
Authors: Beilharz Peter 
Published: July 2023

Modernity and the Holocaust is now thirty years old. How should we respond to the book, its controversy, and its history or context? In this essay I offer three steps as a way into this labyrinth. First, I review the core claims of Bauman’s book (1989). Second, I use my four-volume edited collection of essays on his work (2002) as a decade check on its reception. Third, the new volume, Revisiting Modernity and the Holocaust: Heritage, Dilemmas, Extensions (2022) is brought into play as a third optic or time slice. I conclude that the book is a classic, which means we should still read it and use it as a marker, but also that the debate has out of necessity moved on. As Bauman used to say, “The dogs bark, the carnival moves on”.
On “Modernity and the Holocaust” – inspirations and critique after three decades
Authors: Starnawski Marcin 
Published: July 2023

The article discusses the main theses of Zygmunt Bauman’s book Modernity and the Holocaust, the contexts of its writing and its early critical reception in the 1990s. As an introduction to the issue’s theme, it focuses on the proposals for a contemporary interpretation of Bauman’s work put forward by the authors of the articles published in this issue of Studia Litteraria et Historica. In the final section, the author proposes a reading of Modernity and the Holocaust in relation to educational issues raised in the 1960s by Theodor W. Adorno.