bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constrained Trading Networks
Authors: Kizilkale Can , Vohra Rakesh 
Published: May 2023

Trades based on bilateral (indivisible) contracts can be represented by a network. Vertices correspond to agents, whereas arcs represent the nonprice elements of a bilateral contract. Given prices for each arc, agents choose the incident arcs that maximize their utility. We enlarge the model to allow for polymatroidal constraints on the set of contracts that may be traded, which can be interpreted as modeling limited one-for-one substitution. We show that, for two-sided markets, there exists a competitive equilibrium; however, for multisided markets, this may not be possible. Funding: This work was supported by the Defense Advanced Research Projects Agency [Grant HR001118S0045].
Effectiveness of home-based end-of-life care
Authors: Mansoor Mohamed , Hebatalla Abdelaal , Hill James 
Published: May 2023

Commentary on: Shepperd S, Gonçalves-Bradley DC, Straus SE, Wee B. Hospital at home: home-based end-of-life care. Cochrane Database of Systematic Reviews. 2021;Issue 3. 10.1002/14651858.CD009231.pub3 When a person has been diagnosed with a terminal illness and has less than 6 months to live, and curative treatments are no longer effective, end-of-life care or hospice care may be initiated. Studies suggest that approximately 7 million people a year are given this type of care, which strives to reduce distress and improve quality of life for patients and their families by providing comprehensive physical, psychosocial, and spiritual support. Surveys show that most individuals would prefer to receive this care at home when given the option. However, there are still some uncertainties regarding the effects of end-of-life care at home on a range of important patient outcomes. As a result, a Cochrane review was conducted/updated to study the effects of receiving end-of-life care at home, looking at these outcomes. The aim of this commentary is to critically appraise this Cochrane review and expand upon the findings of the review in context to practice.
Associations between long-term fine particulate matter exposure and hospital procedures in heart failure patients
Authors: Catalano Samantha , Moyer Joshua , Weaver Anne , Di Qian , Schwartz Joel D. , Catalano Michael , Ward-Caviness Cavin K. 
Published: May 2023

Background
Ambient fine particulate matter (PM2.5) contributes to global morbidity and mortality. One way to understand the health effects of PM2.5 is by examining its impact on performed hospital procedures, particularly among those with existing chronic disease. However, such studies are rare. Here, we investigated the associations between annual average PM2.5 and hospital procedures among individuals with heart failure.

Methods
Using electronic health records from the University of North Carolina Healthcare System, we created a retrospective cohort of 15,979 heart failure patients who had at least one of 53 common (frequency > 10%) procedures. We used daily modeled PM2.5 at 1x1 km resolution to estimate the annual average PM2.5 at the time of heart failure diagnosis. We used quasi-Poisson models to estimate associations between PM2.5 and the number of performed hospital procedures over the follow-up period (12/31/2016 or date of death) while adjusting for age at heart failure diagnosis, race, sex, year of visit, and socioeconomic status.

Results
A 1 μg/m3 increase in annual average PM2.5 was associated with increased glycosylated hemoglobin tests (10.8%; 95% confidence interval = 6.56%, 15.1%), prothrombin time tests (15.8%; 95% confidence interval = 9.07%, 22.9%), and stress tests (6.84%; 95% confidence interval = 3.65%, 10.1%). Results were stable under multiple sensitivity analyses.

Conclusions
These results suggest that long-term PM2.5 exposure is associated with an increased need for diagnostic testing on heart failure patients. Overall, these associations give a unique lens into patient morbidity and potential drivers of healthcare costs linked to PM2.5 exposure.
Child-appealing packaged food and beverage products in Canada–Prevalence, power, and nutritional quality
Authors: Mulligan Christine , Vergeer Laura , Kent Monique Potvin , L’Abbé Mary R. 
Published: May 2023

Background
Children are frequently exposed to marketing on food packaging. This study evaluated the presence, type and power of child-appealing marketing and compared the nutritional quality of child-appealing vs. non-child-appealing Canadian packaged foods and examined the relationship between nutrient composition and marketing power.

Methods
Child-relevant packaged foods (n = 5,850) were sampled from the Food Label Information Program 2017 database. The presence and power (# of techniques displayed) of child-appealing marketing were identified. Fisher’s Exact test compared the proportion of products exceeding Health Canada’s nutrient thresholds for advertising restrictions and Mann Whitney U tests compared nutrient composition between products with child- /non-child-appealing packaging. Pearson’s correlation analyzed the relationship between nutrient composition and marketing power.

Results
13% (746/5850) of products displayed child-appealing marketing; the techniques used, and the power of the marketing varied (x¯ 2.2 techniques; range: 0–11). More products with child-appealing packaging than with non-child appealing packaging exceeded Health Canada’s thresholds (98% vs. 94%; p < .001). Products with child-appealing packaging (vs. non-child-appealing) were higher in total sugars (median: 14.7 vs. 9 g/RA; p < .001) and free sugars (11.5 vs. 6.2 g/RA; p < .001), but lower in all other nutrients. There was weak overall correlation between marketing power and nutrient levels. Results varied by nutrient and food category.

Conclusions
Unhealthy products with powerful child-appealing marketing displayed on package are prevalent in the food supply. Implementing marketing restrictions that protect children should be a priority.
Bleb analysis using anterior segment optical coherence tomography after trabeculectomy with amniotic membrane transplantation
Authors: Kim Hwayeong , Moon Sangwoo , Kim Eunah , Kim Jinmi , Lee Jiwoong 
Published: May 2023

Introduction
Little has been known about the intrableb structures associated with bleb function after trabeculectomy with amniotic membrane transplantation (AMT). The aim of this study is to analyze the characteristics of intrableb structures using anterior segment optical coherence tomography (AS-OCT) after trabeculectomy with AMT.

Methods
A total of 68 eyes of 68 patients with primary open-angle glaucoma who underwent trabeculectomy with AMT were included. Surgical success was defined as intraocular pressure (IOP) ≤ 18 mmHg and IOP reduction of ≥ 20% without medication on AS-OCT examination. Intrableb parameters, including bleb height, bleb wall thickness, striping layer thickness, bleb wall reflectivity, fluid-filled space score, fluid-filled space height, and microcyst formation were evaluated using AS-OCT. Logistic regression analysis was performed to determine factors associated with IOP control.

Results
Of the 68 eyes, 56 eyes were assigned to the success group and 12 eyes to the failure group. In the success group, bleb height (P = 0.009), bleb wall thickness (P = 0.001), striping layer thickness (P = 0.001), fluid-filled space score (P = 0.001), and frequency of microcyst formation (P = 0.001) were greater than those in the failure group. Bleb wall reflectivity was higher in the failure group than in the success group (P < 0.001). In the univariate logistic regression analysis, previous cataract surgery was significantly associated with surgical failure (odds ratio = 5.769, P = 0.032).

Conclusion
A posteriorly extending fluid-filled space, tall bleb with low reflectivity, and thick striping layer were characteristics of successful filtering blebs after trabeculectomy with AMT.
Cognitive performance of 4-6-year-old children: a longitudinal study
Authors: Utami Nur Handayani , Sekartini Rini , Kolopaking Risatianti , Besral Besral , Khusun Helda 
Published: May 2023

Background Many children in low and middle-income countries (LMIC) have reduced cognitive abilities, but few studies have explored the influencing factors.
Objective To determine the determinants of children's low cognitive development at 4 to 6-year-old.
Methods This is a retrospective cohort study in year 2021. The data was obtained from Bogor Longitudinal Study of Child Growth and Development (BLSCGD) that started from year 2012. For this analysis, we considered 165 of children aged 4-6 years. The dependent variable in this analysis was cognitive development as measured by the Indonesian Wechsler Preschool and Primary Scale of Intelligence (WPPSI) with the indicators of full-scale IQ (FSIQ), verbal IQ (VIQ) and performance IQ (PIQ). The independent variables were determinants of children’s cognitive development at 4-6 years, consisted of socio-demographic factors, determinants from early life (0-23 months), as well as determinants from current conditions. Multivariate analysis done with the logistic regression test.
Results Bivariate analysis revealed that paternal education level was significantly associated with FSIQ and inadequate calorie intake in infancy and poor child stimulation were significantly associated with VIQ. In the final model of multivariate analysis, low paternal education level retained a significant association with FSIQ. Psychosocial stimulation was significantly associated with VIQ and inadequate calorie intake during infancy was significantly associated with PIQ.
Conclusion Low paternal education level and inadequate psychosocial stimulation are risk factors for reduced child cognitive development in 4-6-year-olds. Inadequate calorie intake in infancy even though not statistically significant it has high OR values for low VIQ and PIQ, thus the results showed the importance of calory intake in infancy.
Predictive factors of advanced chronic kidney disease in children with congenital anomalies of kidney and urinary tract
Authors: Puspitarini Dea , Herini Elisabeth Siti , Satria Cahya Dewi , Hermawan Kristia 
Published: May 2023

Background Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease (CKD) in children. Delayed diagnosis of CAKUT due to lack of universal screening (such as prenatal ultrasound screening or postnatal ultrasound screening in neonates with risk of CAKUT) has led to more cases of advanced CKD in children. CKD has high morbidity and mortality, and early detection is required to prevent the progression of CKD.
Objective To determine the factors that predict the development of advanced CKD in children with CAKUT.
Methods This retrospective cohort study included children with CAKUT at Dr. Sardjito Hospital, Yogyakarta, Indonesia from January 2016 to February 2021. Patients who were diagnosed with CAKUT were followed up to 5 years or until the onset of advanced CKD. Advanced CKD was defined as a decreased estimated glomerular filtration rate (eGFR) of less than 30mL/min/1.73m2 based on the revised Schwartz formula. CKD progression-free survival was determined with Kaplan-Meier and Cox regression analyses.
Results Among 62 subjects with CAKUT, 7 (11.3%) subjects progressed to advanced CKD. The mean time of advanced CKD progression was 52.2 (95%CI 46.9 to 57.5) months. The overall incidence rate was 22 per 1,000 person-years. Based on Kaplan-Meier analysis, children with eGFR <60 mL/min/1.73m2 at the time of diagnosis had more rapid progression to advanced CKD than patients with eGFR ?60 mL/min/1.73m2 [40.2 (95%CI 33.4 to 46.6) months vs. 58.2 95%CI 46.9 to 57.5) months; P=0.02, respectively].
Conclusion Reduced eGFR at the time of diagnosis showed rapid progression to advanced CKD.
Zum Verhältnis von Originalerhalt und Digitalisierung von schriftlichem Kulturgut
Authors: Frohmann Jakob , Kistenich-Zerfaß Johannes , Müller Maria Elisabeth , Preuss Stephanie , Sorbello Staub Alessandra , Scherr Laura , Stumpf Marcus 
Published: May 2023

Zusammenfassung
Beim Erhalt analogen schriftlichen Kulturguts in seiner Entstehungsform wurden im vergangenen Jahrzehnt signifikante Fortschritte erzielt. Zuvorderst sind hierfür die Koordinierungsstelle zur Erhaltung des schriftlichen Kulturguts (KEK), Förderprogramme des Bundes und der Länder, der Ausbau von Infrastrukturen und ein leistungsfähiger Dienstleistermarkt verantwortlich. Bestandsschonend erzeugte Digitalisate schützen Originale vor Nutzungsschäden. Im Sinne der Bewahrung des kulturellen Erbes zurückzuweisen sind Vorstellungen, zugunsten der Digitalisierung den Originalerhalt zu vernachlässigen, wie es die Strategie des Bundesarchivs vorsieht. Denn: Nichts kann das Original vollumfänglich ersetzen.
Adverse outcomes and maternal complications in pregnant women with severe-critical COVID-19: a tertiary center experience
Authors: Sinaci Selcan , Tanacan Atakan , Besimoglu Berhan , Menekse Beser Dilek , Uyan Hendem Derya , Tugrul Ersak Duygu , Atalay Aysegul , Kaya Ecem , Ozden Tokalioglu Eda , Cankar Dal Hayriye , Ocal Doga Fatma , Erdem Deniz , Izdes Seval , Moraloglu Tekin Ozlem , Ates İhsan , Turan Sema , Sahin Dilek 
Published: May 2023

Abstract

Objectives
This study aimed to present perinatal outcomes, clinical challenges, and basic ICU management in pregnant women with severe-critical COVID-19 at our tertiary referral center.

Methods
In this prospective cohort study, patients were divided into two groups, whether they survived or not. Clinical characteristics, obstetric and neonatal outcomes, initial laboratory test results and radiologic imaging findings, arterial blood gas parameters at ICU admission, and ICU complications and interventions were compared between groups.

Results
157 of the patients survived, and 34 of the patients died. Asthma was the leading health problem among the non-survivors. Fifty-eight patients were intubated, and 24 of them were weaned off and discharged healthfully. Of the 10 patients who underwent ECMO, only 1 survived (p<0.001). Preterm labor was the most common pregnancy complication. Maternal deterioration was the most common indication for a cesarean section. Higher neutrophil-to-lymphocyte-ratio (NLR) values, the need for prone positioning, and the occurrence of an ICU complication were important parameters that influenced maternal mortality (p<0.05).

Conclusions
Overweight pregnant women and pregnant women with comorbidities, especially asthma, may have a higher risk of mortality related to COVID-19. A worsening maternal health condition can lead to increased rates of cesarean delivery and iatrogenic prematurity.
Analytical chemistry of some trace elements inTamarix gallicaL. using instrumental neutron activation analysis (INAA)
Authors: Nedjimi Bouzid 
Published: May 2023

AbstractSalt cedar (Tamarix gallicaL.) is an important xero–halophytic tree used for its medicinal properties to treat cancer, gastrointestinal syndromes, diabetes and infections. In the present investigation, instrumental neutron activation analysis (INAA) was carried out to evaluate some major and trace elements (As, Ba, Br, Ca, Ce, Co, Cr, Cs, Eu, Fe, K, La, Na, Rb, Sb, Sc, Sm, Tb, Th, and Zn) in this species. The quality of the results was assessed by the analysis of CRM-GSV4 tea leaves; a good agreement was achieved between the measured and recommended data. The results show thatT. gallicacontained high levels of Ca, K, Na and Fe, while elements toxic to humans (As, Br, and Sb) were below the tolerable limits reported in the World Health Organization database (WHO/FAO). Macro–and microelements essential to humans were present inT. gallicaleaves with significant levels in the following order: Ca > Na > K > Fe > Zn > Cr > Co.T. gallicacould provide a new promising therapeutic source for pharmacological purposes.
Study on the properties of amide Gemini surfactants
Authors: Cai Yongchen , Xu Hujun , Ling Peng 
Published: May 2023

Abstract
In this study, the properties of amide Gemini surfactants (DLP-12, DLP-14 and DLP-16) were investigated. The results showed that these surfactants have good wettability and solubility, but these properties deteriorate with increasing hydrophobic chain length. The critical micelle concentrations (CMC) measured by the Wilhelmy method and by the steady-state fluorescence spectroscopy were similar and showed the same trend: The CMC values decreased with increasing hydrophobic chain length. The solubilization capacities in toluene were (6320, 6440 and 6680) mL/mol for DLP-12, DLP-14 and DLP-16, respectively, indicating an improvement in solubilization ability. Thermal stability experiments showed that the initial decomposition temperatures of the three surfactants were (301, 320 and 331) °C, respectively, indicating good thermal stability of these surfactants.
Domain-General and Domain-Specific Electrophysiological Markers of Cognitive Distance Coding forWhat,Where, andWhenMemory Retrieval
Authors: Park Sang-Eon , Lee Jeonghyun , Lee Sang Ah 
Published: May 2023

Thewhat,where, andwhencomponents of episodic memory can be differentiated based on their distinctive domain-specific underlying neural correlates. However, recent studies have proposed that a common neural mechanism of conceptual mapping may be involved in the coding of cognitive distance across all domains. In this study, we provide evidence that both domain-specific and domain-general processes occur simultaneously during memory retrieval by identifying distinctive and common neural representations for mappingwhat(i.e., semantic distance),where(i.e., spatial distance), andwhen(i.e., temporal distance) using scalp EEG from 47 healthy participants (age 21-30, 26 male and 21 female). First, we found that all three components commonly showed a positive correlation between cognitive distance and slow theta power (2.5-5 Hz) in parietal channels. Meanwhile, fast theta power (5-8.5 Hz) specifically represented spatial and temporal distance in occipital and parietal channels, respectively. Additionally, we identified a unique correlate of temporal distance coding in frontal/parietal slow theta power during the early phase of retrieval. All of the above neural markers of cognitive mapping, both domain-general and specific, were associated with individual differences inwhat, where, and whenmemory accuracy.SIGNIFICANCE STATEMENTThe Cognitive Map Theory was originally founded to explain how we remember and organize the immense amount of spatial information that we face when we navigate. However, memory research has recently trended in the direction of emphasizing the generalizability of cognitive mapping mechanisms to information in any domain, represented as distances in an abstract conceptual space. In a single study, we show that both common and unique neural coding of semantic distance (i.e.,what), spatial distance (i.e.,where), and temporal distance (i.e.,when) simultaneously support episodic memory retrieval. Our results suggest that our ability to accurately distinguish between memories is achieved through an integration of domain-specific and domain-general neurocognitive mechanisms that work in parallel.
Nonspecific Diagnoses and Return Visits Among Children Discharged From the Emergency Department
Authors: Ramgopal Sriram 
Published: May 2023

OBJECTIVES
Previous work has suggested an association between diagnostic uncertainty and the use of nonspecific diagnostic billing codes. We sought to evaluate differences in emergency department (ED) return visits among children discharged from the ED with specific and nonspecific discharge diagnosis codes.

METHODS
We performed a retrospective study including children (aged &lt;18 years) discharged from 40 pediatric EDs between July 2021 and June 2022. Our primary and secondary outcomes were 7-day and 30-day ED return visits, respectively. Our predictor of interest was diagnosis, classified as nonspecific (only signs/symptoms diagnoses, e.g., “cough”) or specific (≥1 specific diagnosis, e.g., “pneumonia”). We evaluated for associations using Cox proportional hazard models adjusted for race/ethnicity, payer status, age, medical complexity, and neighborhood opportunity.

RESULTS
Among 1870100 discharged children, 7-day return visits occurred in 73956 (4.0%); of these, 15.8% had nonspecific discharge diagnoses. The adjusted hazard ratio (aHR) of a return visit among children with a nonspecific diagnosis on their index visit was 1.08 (95% confidence interval, 1.06–1.10). Nonspecific diagnoses with the highest aHR of return visits were for fever, convulsions, digestive system, abdominal signs/symptoms, and headache. Respiratory and emotional/behavior signs or symptoms had a lower aHR of 7-day return visits. The aHR of nonspecific diagnosis on 30-day return visits was 1.01 (95% confidence interval 1.01–1.03).

CONCLUSIONS
Children with nonspecific diagnoses discharged from the ED had distinct patterns of health care utilization compared with those having specific diagnoses. Further research is required to evaluate the role of diagnostic uncertainty with diagnosis code application in the ED.
Applying the SES Framework to coral reef restoration projects on the Pacific coast of Costa Rica
Authors: Palou Zúniga Nohelia , Madrigal Ballestero Róger , Schlüter Achim , Alvarado Juan José 
Published: May 2023

Introduction: Global and local stressors have led to rapid declines in coral reef health. The high rates of coral degradation have motivated restoration initiatives worldwide. Evaluation of these initiatives has provided valuable information regarding coral restoration techniques and limitations faced by projects. However, most of the literature is focused on evaluating metrics related to fragment survival rate and growth, leaving a gap in understanding how social aspects such as governance structure affect project outcomes
Objective: The present research applies the Social-Ecological Systems Framework to identify social and ecological factors contributing to the success of three coral reef restoration projects in Costa Rica.
Methods: Data was gathered from 50 semi-structured interviews with project members, volunteers, tour operators, fishers, and related community and government organizations that were analyzed using the categories determined by the Social-Ecological Systems Framework.
Results: Despite each case’s specific ecological and governance characteristics, research results show that three main steps have contributed to project success. First, the importance of locals having a positive perception of coral reef and project benefits; second, the use of network structure to obtain adequate financial and human resources and third, the importance of compliance with a regulatory framework to create enabling environments for reef restoration.
Conclusions: Results show no universal solutions for coral reef restoration projects. Project managers must understand the ecological and social context of the restoration site to boost the benefits that reef restoration projects can provide, such as an increase in local stewardship, income generation, and the creation of more resilient communities.