bluuebunny/crossref_metadata_2025_split huggingface dataset:
CYTOKINE STATUS IN PATIENTS WITH CHRONIC PERIODONTITIS, ASSOCIATIONS AND CORRELATIONS
Authors: Ssablina Svetlana 
Published: August 2023

Subject. The subject of this research is the immunological parameters of the blood serum and the oral fluid.
Objectives. The objective of this research is to study the levels of serum and oral cytokines TNF-α, IFN-γ, IL-4, MCP-1 in women with secondary amenorrhea for at least one year.
Methodology. There were 109 women under the supervision of the Ural State Medical University Department of Preventive Dentistry and Propedeutics of Dental Disease. The main group consisted of 76 women with generalized moderate chronic periodontitis (K05.31)and secondary amenorrhea for at least one year. The control group consisted of 33 post-menopausal women with generalized slight chronic periodontitis in remission. The patients of the both groups underwent laboratory serum and oral fluid testing using enzyme-linked immunosorbent assay. The levels of cytokines TNF-α, IFN-γ, IL-4, MCP-1 were measured in samples using Vector-Best’s tests systems (Vector-Best, Koltsovo, Novosibirsk Region, Russia). The systemic bone mineral density was measured using dual energy X-ray absorptiometry (DXA) with Discovery W QDR Series X-Ray Bone Densitometer (Hologic Inc., USA).
Conclusion. The levels of interleikins TNF-α, IFN-γ and chemokine MCP-1 were found to be elevated in the blood serum and the oral fluid of women generalized moderate chronic periodontitis against the background of secondary amenorrhea for at least one year. In contrast, the serum values of IL-4 revealed statistically lower levels in comparison with the same values of IL-4 in the patients from the control group. We defined the statistically significant (at 0.05) correlation between parameters of salivary IL-4 levels and spine bone mineral density, and also the statistically significant (at 0.05) weak negative correlation between parameters of blood IFN-γ levels and right-hip bone mineral density.
INFORMATION SPACE AS AN ELEMENT OF PREVENTION OF DENTAL DISEASES IN CHILDREN'S PATIENTS
Authors: Abdrashitova Alena , Safina Roza , Samatova Ravilya , Samerhanova Elvina , Gaynullina Dilya 
Published: August 2023

Subject. Digital technologies and information resources in the prevention of dental diseases in children's patients and their implementation in the activities of dental medical organizations of the Republic of Tatarstan.
The aim. To develop an information resource for children and their parents on the prevention of dental diseases in children's patients.
Results. The main method of influencing the patient is individual preventive counseling. Hygienic education and upbringing should be strictly differentiated by purpose and content, depending on the age of children. However, pediatric dentists have difficulties in teaching the patient and their parents hygiene skills. For example, this may be due to the lack of free time for parents to listen to information from a doctor about the prevention of dental diseases. Parents receive information from the Internet and social groups without thinking about the correctness of the information received and the availability of a scientific approach. The authors have developed a software product for patients of dental medical organizations of children's profile, in which the space is divided by age: from 0 to 17 years.
Conclusions. Despite the scaling up and implementation of preventive measures, the intensity of caries and its increase in many regions of the Russian Federation is at a fairly high level. The lack of information received at the clinical reception, the psycho-emotional component of the child's behavior, the lack of a scientific approach in the Internet information networks lead to low effectiveness of prevention programs. That is why one of the main directions in healthcare is the prevention of diseases, as well as the formation of a healthy lifestyle for both adults and children. The use of the developed product provides various advantages both for the dental medical organization and for patients and their parents. But most importantly, this will increase the effectiveness of preventive measures in children's patients.
EVALUATION OF THE EFFECTIVENESS OF THE USE OF A SYNBIOTIC COMPLEX CONTAINING STREPTOCOCCUS THERMOPHILUS LYSATE AMONG ADOLESCENTS WITH A HIGH RISK OF CARIES
Authors: Kisel'nikova Larisa , Sadovskiy Vladimir , Alekseeva Irina , Ostrovskaya Irina , Ostrovskaya Yulia 
Published: August 2023

Relevance. Assessment of the risk of occurrence, prevention and treatment of caries and gingivitis in adolescents.
Objective. To evaluate the effectiveness of the use of an oral rinse containing Streptococcus thermophilus lysate in adolescents with a high risk of caries.
Materials and methods. The examined 25 adolescents aged 11 to 18 years used a mouthwash "Dentabalance ®" synbiotic complex for a month. The effectiveness of preventive and therapeutic measures was evaluated before and after a month of using the rinse aid by the oral hygiene index OHI-S, periodontal index PMA and indicators of mixed saliva by determining the activity of enzymes by spectrophotometric method: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alkaline phosphatase (alkaline phosphatase) in IU/l; by gas-liquid chromatography, the amount of acetic, propionic and butyric acids in mol/l.
Results. High index values were observed in adolescents with a high risk of caries of permanent teeth: CPU (6,7), OHI-S (2,43 ± 0,07), PMA (62,1 ± 3,0%). In the mixed saliva, increased activity of enzymes was detected, the values of which were AST — 42.0 ± 8.1IU/l; LDH — 490 ± 51.2 IU/l; SCHF — 30.6 ± 1.94IU /l, the indicators of acetic and propionic acids were 2.38 ± 0.48 mol/l and 0.25 ± 0.03 mol/l, respectively, and the content of butyric acid was not determined.
After the use of a mouthwash containing Streptococcus thermophilus lysate by adolescents, the indicators of the hygiene index OHI-S decreased statistically significantly (p < 0.05) by 54.1% and the values of the PMA index by 53.3%; in mixed saliva, a decrease in the activity of AST was determined by 3.5 times, LDH by 4.7 times, alkaline phosphatase by 1.4 times, and also, the number of short-chain organic acids — acetic by 4.7 times and propionic by 1.4 times.
Conclusions. The Dentabalance ® mouthwash is a synbiotic complex containing Streptococcus thermophilus lysate, has an anti-carious and anti-inflammatory effect, which allows it to be recommended for use by adolescents with a high risk of caries and gingivitis.Relevance: Due to the high prevalence of caries and inflammatory lesions of periodontal tissues in adolescents, the assessment of the risk of occurrence, prevention and treatment of these diseases remains relevant.
PELATIHAN PRODUCT BRANDING SEBAGAI OPTIMALISASI STRATEGI PEMASARAN BAGI UMKM
Authors: Mahfirah Titis Fatarina , Rahmi  , Haneul  , Haura Tazkia , Putri Clara Alika 
Published: August 2023

The importance of small and medium enterprises (SMEs) for the Indonesian economy has become an important concern. Especially during the COVID-19 pandemic, SMEs in Indonesia has experienced an increase and has become the most stable sector while other businesses, including large companies, have been affected by COVID-19. However, as SMEs increases, competition also increases. To help SMEs compete in the market, innovation such as building branding is needed. However, many MSMEs have not mastered the application of branding in their business. To this end, product branding training is organized for SMEs trained by Suku Dinas PPKUKM Kota Administrasi Jakarta Timur. This training is an implementation of cooperation between the S1 Management Study Program Faculty of Economics Universitas Negeri Jakarta and Suku Dinas PPKUKM Kota Administrasi Jakarta Timur. The training is conducted online using the Zoom platform. The implementation of the activity begins with the preparation stage, the implementation stage, activity evaluation, reporting and publication of activity outcomes. As a result, SMEs understand the importance of branding for their business. In addition, SMEs are also able to determine the branding strategy that they will implement in their business.

Abstrak
Tingginya peranan UMKM untuk perekonomian Indonesia menjadi perhatian penting. Terlebih pada saat pandemi COVID-19, UMKM di Indonesia mengalami peningkatan dan menjadi bidang yang paling stabil disaat usaha sektor lain termasuk perusahaan besar goyah akibat adanya COVID-19. Namun, dengan meningkatnya UMKM tentu persaingan ikut meningkat. Untuk membantu UMKM bersaing di pasarnya, diperlukan inovasi seperti membangun branding. Namun, banyak pelaku UMKM yang belum menguasai penerapan branding dalam usaha mereka. Untuk itu, diselenggarakan pelatihan mengenai product branding bagi UMKM yang dibina oleh Suku Dinas PPKUKM Kota Administrasi Jakarta Timur. Pelatihan ini merupakan implementasi kerja sama antara Program Studi S1 Manajemen Fakultas Ekonomi Universitas Negeri Jakarta dengan Suku Dinas PPKUKM Kota Administrasi Jakarta Timur. Pelatihan dilaksanakan secara daring menggunakan platform Zoom. Pelaksanaan kegiatan diawali dengan tahap persiapan, tahap pelaksanaan, evaluasi kegiatan, pelaporan dan publikasi luaran kegiatan. Hasilnya, pelaku UMKM memahami pentingnya branding untuk usaha mereka. Selain itu, pelaku UMKM juga mampu untuk menentukan strategi branding yang akan mereka terapkan dalam usahanya.
Life Cycle Assessment of Improved Oil Recovery While Helping to Achieve Net Zero Emissions from Shale Reservoirs
Authors: Bao Xiaolin , Amaya Alfonso Fragoso , Aguilera Roberto 
Published: August 2023

Summary
Shale reservoirs will help to meet oil demand that is forecasted to continue increasing for several years. Oil recovery from shales is low and has been reported to range between 5% and 10%. The objective of this paper is to show how oil recovery from shale can be improved while simultaneously reducing CO2 emissions, thus contributing to the goal of a net-zero future.
The proposed methodology shows how oil recovery from shales can be increased while simultaneously storing CO2 in undepleted (as opposed to depleted) shale oil reservoirs and consequently contributing to a future with net-zero emissions. The methodology is developed with the use of reservoir simulation and is achieved by performing the following procedure: (1) Start huff ’n’ puff CO2 injection 2 or 3 years after the well goes on oil production so the shale reservoir is essentially undepleted, and (2) store CO2 gradually in the shale reservoir during the huff periods, and continuously once the huff ’n’ puff project is finalized.
The simulation model includes a history match period with actual production data from a pilot horizontal well and a forecast period with huff ’n’ puff CO2 injection. Two cases, one with diffusion and one without diffusion, are conducted for evaluating the molecular diffusion effect. The initial reservoir pressure is never exceeded during the life cycle of the project as a safeguard against the possible creation of new fractures or reactivation of faults.
Life cycle assessment (LCA) indicates that the ratio of cumulative stored CO2 to cumulative equivalent CO2 emissions during the project is approximately 31.3%, helping us consequently in the goal to eventually achieve a future with net-zero emissions. A careful literature survey indicates that the methodology proposed in this paper that includes enhanced oil recovery (EOR) by huff ’n’ puff CO2 injection and the simultaneous storage of CO2 in the shale reservoir is novel and has not been considered previously in geoscience or petroleum engineering literature.
Intelligent Transport Systems as the Basis of de Lege Ferenda of the Transport System of the Russian Federation
Authors: Bazhina M. A. 
Published: August 2023

Objective: to research the trends of legal regulation of using intelligent transport systems under digital transformation of the transport sector of economy, namely, the growing importance of intelligent transport systems in the future transport system of the Russian Federation.Methods: systemic-structural method is the basis for researching intelligent transport systems. It enables to study the architecture of intelligent transport systems as a complex structural unity. Also, comparative-legal method was used, aimed at illustrating the differences and similarities in the legal regulation of intelligent transport systems. Methods of legal modeling and forecasting, as well as formal-logic method, served as secondary methods to comprehensively study the legal regulation of intelligent transport systems.Results: the article presents conceptual approaches to defining the notion of “intelligent transport systems” and outlining the hierarchy of intelligent transport systems, which play a fundamental role in building the transport sector. Based on the analysis, conclusions are made about the vectors of forming transport legislation, aimed at regulating the use of intelligent transport systems.Scientific novelty: the article provides a conceptual approach to forming the legal regulation of intelligent transport systems. To this end, the issue is considered about the essential content of the notion of “intelligent transport systems” at legal and scientific levels; the current terminological problems in building the legal regulation are shown. Analysis of the architecture of intelligent transport systems allowed for the first time to formulate the basic approaches to shaping the legal regulation of its individual elements (including highly automated and fully automated transport means, “smart” infrastructure, etc.) not in isolation but as constituent parts of the whole matter.Practical significance: the presented materials and conclusions facilitate the development of legal regulation of transport industry under digital transformation. The article accentuates the legal regulation of intelligent transport systems taking into account their technical and technological features. It is the intelligent transport systems that are de lege ferenda of the transport system, which determines the vector of transformation of transport legislation. In turn, development of the legal bases allows broadening the geography of introducing technical novelties and making their application much more large-scale.
Sovereignty vs. Digital Sovereignty
Authors: Robles-Carrillo M. 
Published: August 2023

Objective: the aim of this paper is to analyze the relationship between sovereignty and digital sovereignty in order to determine whether they are linked or autonomous concepts and in which cases and to what extent there is or is not a connection between the two categories.Methods: the methodology is based on the analysis of international, European and national practice and scientific discourse, taking into account sovereignty and digital sovereignty from a threefold perspective: contextual, conceptual and functional.Results: 1) analysis of the correlation between sovereignty and digital sovereignty showed that both are related concepts; 2) important consequences that digital sovereignty has in the case of States and the European Union are defined: a) there is a substantial difference between sovereignty and digital sovereignty because the former is only applied to States, while the latter is also used in reference to the EU; b) digital sovereignty is not necessarily a consequence or an extension of sovereignty; c) while in the case of States, digital sovereignty is justified as a safeguard of traditional sovereignty, in case of European Union its function must necessarily be different, since the European Union lacks sovereignty.Scientific novelty: the analysis of this relationship provides an objective scientific premise for a comprehensive understanding of the idea of digital sovereignty. From the perspective of the context where they operate, as well as their concept and functions, sovereignty and digital sovereignty seem to be autonomous and, in some cases, complementary categories.Practical significance: the dual functionality of digital sovereignty as a concept attached to national sovereignty and as an autonomous concept helps to explain the use of this category in the case of states and in the case of an organization such as the European Union, as well as the differences in its scope and meaning in each scenario.
Features of Online Settlement of Consumer Disputes by e-commerce Platforms in the People’s Republic of China
Authors: Ermakova E. P. 
Published: August 2023

Objective: to research the features of online dispute settlement by e-commerce platforms in the People’s Republic of China, to reveal positive features and drawbacks of ODS technologies applied by the platforms.Methods: empirical methods of comparison, description, interpretation; theoretical methods of formal and dialectical logic. Specific scientific methods were used: legal-dogmatic and the method of legal norms interpretation.Results: it was found that the internal ODS model on e-commerce Taobao ODS platforms is a direct, clear and effective means of online resolution of consumer disputes. However, being a non-independent “third party”, the internal ODS mechanism of e-commerce platforms will never be able to substitute other external systems of dispute resolution. ODS relies on the data and Internet processes much stronger than traditional dispute resolution. Among the many safety factors emerging as a result of online processes, ODS creates the risk of data leakage, lack of confidentiality and unsafe consumer protection. ODS also causes concerns due to traditional principles of justice such as objectivity, confidentiality and safety of data in the process of dispute settlement. Not only the People’s Republic of China but any country introducing the ODS technologies into the procedures of dispute resolution should take serious measures to ensure the ODS processes are just, unbiased and guarantee observance of procedural rights. Scientific novelty: consists in a complex research of online dispute settlement by e-commerce platforms in the People’s Republic of China, the practice of implementation thereof has its specific features stemming from the model of self-regulation of thee relations, further stipulated by normative legal acts of the People’s Republic of China and reflected in the activity of private ODS platforms.Practical significance: is due to the current absence of possibility to apply the legal norms and rules, taking into account the specific features of ODS technologies on private platforms, to the relations using such technologies. The main provisions and conclusions of the research can be used to improve the mechanisms of legal regulation of ODS technologies in the procedural legislation of the Russian Federation.
Genesis and Prospects of Development of Legal Regulation of Digital Financial Assets in the Russian Federation
Authors: Peretolchin A. P. 
Published: August 2023

Objective: to research the existing problems and promising directions of the legal regulation of digital financial assets as a relatively new tool of the modern digital economy.Methods: the methodological basis of the work is the set of scientific cognition methods such as theoretical analysis, research, comparison, synthesis, and summarization of scientific literature.Results: the work analyzes the existing approaches to legal regulation of digital financial assets in the Russian Federation and some foreign countries, reveals the existing gaps in the Russian legislation in the field of circulation of digital financial assets, gives estimation to the prospects of development of the legal regulation of these tools and forms proposals for its improving. Also, during the research, the approaches to legal regulation of digital currencies and digital financial assets, adopted in certain foreign countries, were analyzed, the trends were considered, and the positive and negative aspects of using cryptographic algorithms for the goals in economic and juridical spheres of the global economy were reflected.Scientific novelty: within the work, the topical issues of legislative regulation of such a relatively new notion as digital financial assets are considered. The positions of Russian and foreign jurist are considered concerning the existing problems and risks associated with “tokenization” and “blockachainization” of private law. Besides, the author comes to a conclusion about the existence of significant gaps in the current approach to legal regulation of digital financial assets, indicates them and proposes certain mechanisms to solve these problems.Practical significance: is due to the imperfect current legislation in the sphere of relations occurring when using the technologies based of distributed ledger, including digital financial assets. Research of these problems allows evaluating the risks, considering the existing ways of overcoming and solving the emerging disputable questions. Also, the conclusions obtained can be used to improve the Russian legislation, as well as in the academic literature devoted to the topical issues of developing the digital legislation.
Facial Recognition Technology and Ensuring Security of Biometric Data: Comparative Analysis of Legal Regulation Models
Authors: Utegen D. , Rakhmetov B. Zh. 
Published: August 2023

Objective: to specify the models of legal regulation in the sphere of biometric identification and authentication with facial recognition technology in order to elaborate recommendations for increasing information security of persons and state-legal protection of their right to privacy.Methods: risk-oriented approach in law and specific legal methods of cognition, such as comparative-legal analysis and juridical forecasting, are significant for the studied topic and allow comparing the legal regulation models used in foreign countries and their unions in the sphere of biometric identification and authentication with facial recognition systems, forecasting the possible risks for the security of biometric data, taking into account the prospects of further dissemination of the modern facial recognition technology, and to shape recommendations on legal protection of biometric data.Results: the ways are proposed to further improve legislation of the Republic of Kazakhstan and other countries currently developing the legal regulation of biometric data, regarding the admissible criteria for using the facial recognition technology, the elaboration of categorization of biometric systems with a high and low risk levels (by the example of the experience of artificial intelligence regulation in the European Union), and the necessity to introduce a system of prohibitions of mass and unselective surveillance of humans with video surveillance systems, etc.Scientific novelty: consists in identifying a positive advanced foreign experience of developing legal regulation in the sphere of facial recognition based on biometry (European Union, the United States of America, the United Kingdom of Great Britain and Northern Ireland), which can be used for further improvement of the national legislation in order to create more effective mechanisms of legal protection of personal data, including biometric information.Practical significance: based on risk-oriented approach and comparative analysis, the research allows elaborating measures for enhancing the legal protection of biometric data and ensuring effective protection of civil rights and freedoms by forecasting further expansion of the modern facial recognition technology.