bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-lagged analysis of problematic social media use and phubbing among college students
Authors: Lv Shuai , Wang Hui 
Published: February 2023

Abstract
Background
Phubbing is a commonly seen phenomenon that has emerged in recent years among groups of college students, posing a rising challenge to educators. We conduct research in which the reciprocal relationship between problematic social media use and phubbing is explored and analysed quantitatively, aiming to discover reliable theoretical support to work out an appropriate intervention on students’ phubbing for students’ mental health concerns.

Methods
Using the problematic social media use scale and the phubbing scale, 328 college students from four universities in Shandong Province were enrolled in a two-stage longitudinal follow-up study for 20 months from December 2019 to August 2021. A cross-lagged model was constructed to explore the reciprocal relationship between problematic social media use and phubbing. The results of correlation analysis showed that problematic social media use was positively correlated with phubbing at both time points (r = 0.51, 0.53, P < 0.01).

Results
The results of cross-lagged regression analysis showed that the predictive effect of pretest problematic social media use on posttest problematic social media use was statistically significant (β = 0.24, P < 0.01). There was statistical significance in the prediction effect of pretest phubbing on posttest phubbing (β = 0.16, P < 0.05). Pretest problematic social media use had statistical significance in predicting posttest phubbing (β = 0.22, P < 0.01), and there was no statistical significance in the prediction of pretest phubbing on posttest problematic social media (β = 0.16, P < 0.05).

Conclusion
The problematic social media use of college students is closely related to phubbing, and problematic social media use can predict phubbing.
The sound of stress recovery: an exploratory study of self-selected music listening after stress
Authors: Adiasto Krisna , van Hooff Madelon L. M. , Beckers Debby G. J. , Geurts Sabine A. E. 
Published: February 2023

Abstract
Background
Empirical support for the notion that music listening is beneficial for stress recovery is inconclusive, potentially due to the methodological diversity with which the effects of music on stress recovery have been investigated. Little is presently known about which recovery activities are chosen by individuals for the purpose of stress recovery, and whether audio feature commonalities exist between different songs that are selected by individuals for the purpose of stress recovery. The current pre-registered study investigated whether audio feature commonalities can be extracted from self-selected songs for the purpose of stress recovery. Furthermore, the present study exploratorily examined the relationship between audio features and participants’ desired recovery-related emotions while listening and after listening to self-selected music.

Methods
Participants (N = 470) completed an online survey in which they described what music they would listen to unwind from a hypothetical stressful event. Data analysis was conducted using a split-sample procedure. A k-medoid cluster analysis was conducted to identify audio feature commonalities between self-selected songs. Multiple regression analyses were conducted to examine the relationship between audio features and desired recovery emotions.

Results
Participants valued music listening as a recovery activity to a similar extent as watching TV, sleeping, or talking to a significant other. Cluster analyses revealed that self-selected songs for the purpose of stress recovery can be grouped into two distinct categories. The two categories of songs shared similarities in key, loudness, speechiness, acousticness, instrumentalness, liveness, musical valence, tempo, duration, and time signature, and were distinguished by danceability, energy, and mode. No audio features were significantly associated with participants’ desired recovery emotions.

Conclusions
Although a comprehensive portrait of the relationship between audio features and stress recovery still warrants further research, the present study provides a starting point for future enquiries into the nuanced effects of musical audio features on stress recovery.
Psychological distress and associated factors among cancer patients in public hospitals, Addis Ababa, Ethiopia: a cross-sectional study
Authors: Negussie Frehiwot , Giru Berhanu Wordofa , Yusuf Nete Tewfik , Gela Debela 
Published: February 2023

AbstractBackgroundCancer has great implications for psychological, social, economic, and emotional dimensions. Psychological distress is overwhelming among cancer patients following a confirmed diagnosis. However, little is known about the prevalence of psychological distress and associated factors among cancer patients in Africa Sub-Saharan. Thus, this study aimed to assess the prevalence of psychological distress and associated factors among cancer patients in public hospitals in Addis Ababa, Ethiopia.MethodsAn institution-based cross-sectional study was conducted among cancer patients from September 15, 2019, to June 30, 2020. A total of 386 cancer patients selected through a simple random sampling technique participated in the study. Data were collected by an interview-administered questionnaire to evaluate psychological distress with a distress thermometer and social support with the Oslo 3-items Social Support Scale. The collected data were entered into Epi-data version 4.2 and exported into SPSS 25 for analysis, and then binary and multivariate logistic regressions were done to identify the association between dependent and independent variables.ResultsA total of 386 study participants were included in the study with a response rate of 91.4%. The prevalence of psychological distress among cancer patients in public hospitals in Addis Ababa, Ethiopia was 64.5%. Age > 45 years [AOR = 0.41; 95% CI (0.22–0.77)], marital status of being divorced [AOR = 3.3; 95%CI (1.23–8.71)] and married [AOR = 3.2; 95%CI (1.03–10.40)], rural residence [AOR = 1.5; 95%CI (1.15–5.18)], cancer stage II [AOR = 3.9; 95%CI (1.90–15.50)], stage III [AOR = 3.5;95%CI (1.45–8.44)] and stage IV [AOR = 3.4; 95%CI (1.90–10.11)], co-morbidity [AOR = 0.07; 95%CI: (0.03–0.17)], and moderate social support [AOR = 0.36; 95%CI (0.14–0.60)] and strong social support [AOR = 0.06; 95%CI (0.03–0.12)] were found to be significantly associated with psychological distress.ConclusionThe prevalence of psychological distress among cancer patients in public hospitals in Addis Ababa, Ethiopia was high, and age, marital status, place of residence, cancer stage, co-morbidity, and social support were associated with psychological distress. Therefore, interventions focusing on these findings require special emphasis during designing interventions aimed at decreasing psychological distress.
Investigating coordinated account creation using burst detection and network analysis
Authors: Bellutta Daniele , Carley Kathleen M. 
Published: February 2023

AbstractDemocracies around the world face the threat of manipulation of their electorates via coordinated online influence campaigns. Researchers have responded by developing valuable methods for finding automated accounts and identifying false information, but these valiant efforts often fall into a cat-and-mouse game with perpetrators who constantly change their behavior. This has forced several researchers to go beyond the detection of individual malicious actors by instead identifying the coordinated activity that propels potent information operations. In this vein, we provide rigorous quantitative evidence for the notion that sudden increases in Twitter account creations may provide early warnings of online information operations. Analysis of fourteen months of tweets discussing the 2020 U.S. elections revealed that accounts created during bursts exhibited more similar behavior, showed more agreement on mail-in voting and mask wearing, and were more likely to be bots and share links to low-credibility sites. In concert with other techniques for detecting nefarious activity, social media platforms could temporarily limit the influence of accounts created during these bursts. Given the advantages of combining multiple anti-misinformation methods, we join others in presenting a case for the need to develop more integrable methods for countering online influence campaigns.
Nanomaterial-based biohybrid hydrogel in bioelectronics
Authors: Shin Minkyu , Lim Joungpyo , An Joohyun , Yoon Jinho , Choi Jeong-Woo 
Published: February 2023

AbstractDespite the broadly applicable potential in the bioelectronics, organic/inorganic material-based bioelectronics have some limitations such as hard stiffness and low biocompatibility. To overcome these limitations, hydrogels capable of bridging the interface and connecting biological materials and electronics have been investigated for development of hydrogel bioelectronics. Although hydrogel bioelectronics have shown unique properties including flexibility and biocompatibility, there are still limitations in developing novel hydrogel bioelectronics using only hydrogels such as their low electrical conductivity and structural stability. As an alternative solution to address these issues, studies on the development of biohybrid hydrogels that incorporating nanomaterials into the hydrogels have been conducted for bioelectronic applications. Nanomaterials complement the shortcomings of hydrogels for bioelectronic applications, and provide new functionality in biohybrid hydrogel bioelectronics. In this review, we provide the recent studies on biohybrid hydrogels and their bioelectronic applications. Firstly, representative nanomaterials and hydrogels constituting biohybrid hydrogels are provided, and next, applications of biohybrid hydrogels in bioelectronics categorized in flexible/wearable bioelectronic devices, tissue engineering, and biorobotics are discussed with recent studies. In conclusion, we strongly believe that this review provides the latest knowledge and strategies on hydrogel bioelectronics through the combination of nanomaterials and hydrogels, and direction of future hydrogel bioelectronics.Graphical Abstract
Trends and research foci of robotics-based STEM education: a systematic review from diverse angles based on the technology-based learning model
Authors: Darmawansah Darmawansah , Hwang Gwo-Jen , Chen Mei-Rong Alice , Liang Jia-Cing 
Published: February 2023

AbstractFostering students’ competence in applying interdisciplinary knowledge to solve problems has been recognized as an important and challenging issue globally. This is why STEM (Science, Technology, Engineering, Mathematics) education has been emphasized at all levels in schools. Meanwhile, the use of robotics has played an important role in STEM learning design. The purpose of this study was to fill a gap in the current review of research on Robotics-based STEM (R-STEM) education by systematically reviewing existing research in this area. This systematic review examined the role of robotics and research trends in STEM education. A total of 39 articles published between 2012 and 2021 were analyzed. The review indicated that R-STEM education studies were mostly conducted in the United States and mainly in K-12 schools. Learner and teacher perceptions were the most popular research focus in these studies which applied robots. LEGO was the most used tool to accomplish the learning objectives. In terms of application, Technology (programming) was the predominant robotics-based STEM discipline in the R-STEM studies. Moreover, project-based learning (PBL) was the most frequently employed learning strategy in robotics-related STEM research. In addition, STEM learning and transferable skills were the most popular educational goals when applying robotics. Based on the findings, several implications and recommendations to researchers and practitioners are proposed.
Single-time-point dosimetry using model selection and nonlinear mixed-effects modelling: a proof of concept
Authors: Hardiansyah Deni , Riana Ade , Beer Ambros J. , Glatting Gerhard 
Published: February 2023

Abstract
Purpose
This project aims to develop and evaluate a method for accurately determining time-integrated activities (TIAs) in single-time-point (STP) dosimetry for molecular radiotherapy. It performs a model selection (MS) within the framework of the nonlinear mixed-effects (NLME) model (MS–NLME).

Methods
Biokinetic data of [111In]In-DOTATATE activity in kidneys at T1 = (2.9 ± 0.6) h, T2 = (4.6 ± 0.4) h, T3 = (22.8 ± 1.6) h, T4 = (46.7 ± 1.7) h, and T5 = (70.9 ± 1.0) h post injection were obtained from eight patients using planar imaging. Eleven functions were derived from various parameterisations of mono-, bi-, and tri-exponential functions. The functions’ fixed and random effects parameters were fitted simultaneously (in the NLME framework) to the biokinetic data of all patients. The Akaike weights were used to select the fit function most supported by the data. The relative deviations (RD) and the root-mean-square error (RMSE) of the calculated TIAs for the STP dosimetry at T3 = (22.8 ± 1.6) h and T4 = (46.7 ± 1.7) h p.i. were determined for all functions passing the goodness-of-fit test.

Results
The function $$f_{4d} \left( t \right) = A_{1} /\left\{ {\left( {\frac{1 - \alpha }{{\lambda_{1} + \lambda_{{{\text{phys}}}} }}} \right) - \left( {\frac{\alpha }{{\lambda_{2} + \lambda_{{{\text{phys}}}} }}} \right) - \left( {\frac{1 - 2\alpha }{{\lambda_{bc} + \lambda_{{{\text{phys}}}} }}} \right)} \right\} \cdot e^{{ - \lambda_{{{\text{phys}}}} t}} \cdot \left\{ {\left( {1 - \alpha } \right) \cdot e^{{ - \lambda_{1} t}} - \alpha \cdot e^{{ - \lambda_{2} t}} - \left( {1 - 2\alpha } \right) \cdot e^{{ - \lambda_{bc} t}} } \right\}$$

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with four adjustable parameters and $$\lambda_{bc} = \frac{{{\text{ln}}\left( 2 \right)}}{{1\;{\text{ min}}}}$$

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was selected as the function most supported by the data with an Akaike weight of (45 ± 6) %. RD and RMSE values show that the MS–NLME method performs better than functions with three or five adjustable parameters. The RMSEs of TIANLME–PBMS and TIA3-parameters were 7.8% and 10.9% (for STP at T3), and 4.9% and 10.7% (for STP at T4), respectively.

Conclusion
An MS–NLME method was developed to determine the best fit function for calculating TIAs in STP dosimetry for a given radiopharmaceutical, organ, and patient population. The proof of concept was demonstrated for biokinetic 111In-DOTATATE data, showing that four-parameter functions perform better than three- and five-parameter functions.
Distinguishing Killian–Jamieson diverticulum from Zenker’s diverticulum
Authors: Watanabe Yuki , Taniyama Yusuke , Koseki Ken , Ishida Hirotaka , Ozawa Yohei , Okamoto Hiroshi , Sato Chiaki , Unno Michiaki , Kamei Takashi 
Published: February 2023

Abstract
Background
Killian–Jamieson diverticulum, which is a relatively rare pharyngoesophageal diverticulum, is difficult to distinguish from Zenker’s diverticulum. Because major points of the relevant surgical procedures for these two entities differ, it is important to make an accurate diagnosis. We herein report a case of Killian–Jamieson diverticulum initially diagnosed as Zenker’s diverticulum.

Case presentation
A 56-year-old man complaining of discomfort during swallowing was diagnosed with pharyngoesophageal diverticulum. He was initially diagnosed with Zenker’s diverticulum before surgery, but the diverticulum actually arose from the left side of the esophageal wall, at the level of the cricoid cartilage and below the cricopharyngeal muscle. We therefore ultimately diagnosed this case as Killian–Jamieson diverticulum during surgery, and were able to preserve the muscle above the diverticulum, which would normally have to be cut when treating a case of Zenker’s diverticulum.

Conclusion
To make an accurate diagnosis, clinical and surgical findings are important to consider, including the location of the diverticulum and the relationship between the diverticula and cricopharyngeal muscles or between the diverticula, thyroid cartilage and cricoid cartilage.
Transmission sources and severe rat lung worm diseases in travelers: a scoping review
Authors: Meesing Atibordee , Khamsai Sittichai , Sawanyawisuth Kittisak , Tiamkao Somsak , Maleewong Wanchai , Limpawattana Panita , Sawunyavisuth Bundit , Ngamjarus Chetta , Boonsawat Watchara 
Published: February 2023

Abstract
Background
Rat lung worm disease (RLWD) has several clinical forms including eosinophilic meningitis (EOM) and two severe forms, eosinophilic meningoencephalitis (EOME) and eosinophilic radiculomyelitis (EORM). It remains unclear whether transmission sources are associated with severe forms of RLWD. This study aimed to evaluate if transmission factors are related to the severity of RLWD among travelers by using a scoping review of case reports.

Methods
This was a review using five databases to retrieve case reports and case series of travelers with RLWD. Clinical data and transmission sources of reported cases diagnosed as RLWD were retrieved. The outcome of the study was occurrence of severe forms of RLWD defined as EOME, EORM, and combined EOME/EORM.

Results
We retrieved 1,326 articles from five databases and 31 articles were included in the analysis. There were 84 cases eligible from 15 countries. Four cases were excluded. Seventy cases were in EOM group and 10 cases had EOME or EORM. Compared with the EOM group, the EOME, EORM, and combination EOME/EORM group had similar age, sex, and risk factors of consumptions of apple snails, shrimp and prawn, and salad/vegetables. The EOME group had higher proportion of consumption of African snails than the EOM group (60% vs 13.8%). However, only one study reported the consumption of African snails and the heterogeneity between studies and the small sample size impeded direct comparisons between groups.

Conclusions
RLWD in travelers can be found in most continents and mostly get infected from endemic countries of RLWD. Further studies are required to evaluate the association between transmission vectors and severity of RLWD.
Did weekly economic index and volatility index impact US food sales during the first year of the pandemic?
Authors: Das Narasingha , Gangopadhyay Partha 
Published: February 2023

AbstractWe explore the impacts of economic and financial dislocations caused by COVID-19 pandemic shocks on food sales in the United States from January 2020 to January 2021. We use the US weekly economic index (WEI) to measure economic dislocations and the Chicago Board Options Exchange volatility index (VIX) to capture the broader stock market dislocations. We validate the NARDL model by testing a battery of models using the autoregressive distributed lags (ARDL) methodology (ARDL, NARDL, and QARDL specifications). Our study postulates that an increase in WEI has a significant negative long-term effect on food sales, whereas a decrease in WEI has no statistically significant (long-run) effect. Thus, policy responses that ignore asymmetric effects and hidden cointegration may fail to promote food security during pandemics.
Association of tobacco use with the tobacco-related built environment: an ecological study from urban slums of Bhopal, India
Authors: Sabde Yogesh Damodar , Yadav Vikas , Pakhare Abhijit P. , Kumar Sanjeev , Joshi Ankur , Joshi Rajnish 
Published: February 2023

Abstract
Introduction
Tobacco is one of the biggest public health problems and a major risk factor for various non-communicable diseases (NCDs). An important aspect of tobacco control strategy could include modifications in the tobacco-related built environment. This study investigated the association between tobacco shop density and tobacco use prevalence in the urban slums of Bhopal city, India.

Methods
We conducted a cross-sectional survey to obtain the distribution of tobacco-related built environment (tobacco shops) in the neighbourhood (400-m service area) of 32 urban slum clusters of Bhopal. We plotted this distribution using the 'network service area analysis' in ArcMap 10.7.1 software. Then, we used an ecological design to determine the association between tobacco shop density and tobacco use prevalence in these 32 clusters (N = 6214 adult inhabitants). We used multiple linear regression analysis to estimate the regression coefficient (adjusted for socio-demographic variables) between tobacco use and tobacco shop density at the cluster level.

Results
The prevalence of tobacco use among all 32 slum clusters ranged from 22.1 to 59.6% (median 40.9% with IQR 31.8–44.2). There were 194 tobacco shops situated in the neighbourhood of all clusters. The median density of tobacco shops was 59.40/km2 (IQR 39.9–108.1/km2) in the neighbourhoods of slum clusters. Tobacco use prevalence was significantly associated with tobacco shop density (estimate or B = 0.071, p value = 0.002) after adjusting for age, literacy, wealth index, and gender ratio.

Conclusions
Tobacco use prevalence is significantly associated with tobacco shop density in the slums of Bhopal city in central India. We need to develop appropriate built environment interventions to control rampant tobacco use.
ANCHOR CRC: Results From a Single-Arm, Phase II Study of Encorafenib Plus Binimetinib and Cetuximab in Previously Untreated BRAFV600E-Mutant Metastatic Colorectal Cancer
Authors: Van Cutsem Eric , Taieb Julien , Yaeger Rona , Yoshino Takayuki , Grothey Axel , Maiello Evaristo , Elez Elena , Dekervel Jeroen , Ross Paul , Ruiz-Casado Ana , Graham Janet , Kato Takeshi , Ruffinelli Jose C. , André Thierry , Carrière Roussel Edith , Klauck Isabelle , Groc Mélanie , Vedovato Jean-Claude , Tabernero Josep 
Published: February 2023

PURPOSE The positive BEACON colorectal cancer (CRC) safety lead-in, evaluating encorafenib + cetuximab + binimetinib in previously treated patients with BRAFV600E-mutated metastatic CRC (mCRC), prompted the design of the phase II ANCHOR CRC study (ClinicalTrails.gov identifier: NCT03693170 ). ANCHOR CRC aimed to evaluate efficacy, safety, and quality of life with first-line encorafenib + binimetinib + cetuximab in BRAFV600E-mutated mCRC. METHODS In this multicenter, open-label, single-arm study, patients with BRAFV600E-mutated mCRC received oral encorafenib 300 mg once daily and binimetinib 45 mg twice daily in 28-day cycles, plus intravenous cetuximab 400 mg/m2 once on day 1 of cycle 1, then 250 mg/m2 once weekly for the first seven cycles, and 500 mg/m2 once on Days 1 and 15 from cycle 8 onward. The primary end point was locally assessed confirmed objective response rate (cORR), and secondary end points included centrally assessed cORR, progression-free survival, overall survival (OS), quality of life, and safety and tolerability. RESULTS Among 95 patients, the locally assessed cORR was 47.4% (95% CI, 37.0 to 57.9) with all partial responses. Since the lower limit of the 95% CI exceeded 30%, the primary end point was met. With a median follow-up duration of 20.1 months, the median progression-free survival on the basis of local assessments was 5.8 months and the median OS was 18.3 months. Treatment was well tolerated, with no unexpected toxicities. Using Patient Global Impression of Changes, substantial improvement in symptoms was consistently reported in ≥ 30% of patients from cycle 3 to cycle 10. CONCLUSION The ANCHOR CRC study showed that the scientifically driven combination of encorafenib + binimetinib + cetuximab was active in the first-line setting of BRAFV600E-mutated mCRC with a manageable safety profile. Further first-line evaluation is ongoing (ClinicalTrails.gov identifier: NCT04607421 ).