bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of exposure to multiple volatile organic compounds with ultrasound-defined hepatic steatosis and fibrosis in the adult US population: NHANES 2017–2020
Authors: Shao Wentao , Gong Pan , Wang Qihan , Ding Fan , Shen Weiyi , Zhang Hongchao , Huang Anhua , Liu Chengyu 
Published: January 2025

ObjectiveVolatile organic compounds (VOCs) are pervasive environmental pollutants known to impact human health, but their role in liver steatosis or fibrosis is not fully understood. This study investigates the association of urinary VOC mixtures with the risk of liver steatosis and fibrosis in U.S. adult population.MethodsData of 1854 adults from the National Health and Nutrition Examination Survey (NHANES) from 2017.01 to 2020.03 were collected. Vibration Controlled Transient Elastography (VCTE) assessed hepatic steatosis and liver fibrosis via the controlled attenuation parameter (CAP) and liver stiffness measurement (LSM), respectively. The study examined the relationship between urinary exposure biomarkers for 20 VOCs and liver health outcomes using multivariate logistic regression and Bayesian Kernel Machine Regression (BKMR) to evaluate the effects of both individual and mixed VOC exposures.ResultsMultivariate logistic regression analysis revealed that exposure biomarkers for acrolein and crotonaldehyde were positively associated with hepatic steatosis. Conversely, biomarkers for styrene, ethylbenzene, and propylene oxide were negatively associated with hepatic steatosis. Furthermore, biomarkers for 1,3-butadiene and xylene were positively associated with liver fibrosis, while ethylbenzene was negatively associated with this condition. BKMR analysis identified a significant positive joint effect of VOC biomarkers on CAP. Notably, when other VOC-EBs were held at median levels, biomarkers for acrolein and 1,3-butadiene exhibited linear correlations with Ln CAP and hepatic Ln LSM, respectively.ConclusionThe study highlights the potential hepatotoxic effects of VOC mixtures, particularly noting the roles of acrolein and 1,3-butadiene in exacerbating liver steatosis and fibrosis. These findings advocate for further research to explore the mechanistic pathways and conduct longitudinal studies to establish causality and enhance understanding of VOCs’ impact on liver health.
Does the reform of the phased reduction of the pension insurance contribution rate benefit the labor income share of enterprises?
Authors: Dou Chengqiang , Liu Ying 
Published: January 2025

IntroductionThis paper develops a theoretical model to clarify the mechanisms by which pension insurance contribution rate affects the labor income share of enterprises and conducts empirical validation.MethodsUtilizing a difference-in-differences approach, this paper analyzes data from China’s A-share listed companies from 2013 to 2018 to examine the impact and mechanism of the phased reduction of the pension insurance contribution rate on enterprise labor income share.Results and discussionThe phased reduction of the pension insurance contribution rate is beneficial for increasing enterprise labor income shares, with significant variations observed across regions and enterprise ownership types. The actual pension insurance contribution rate and capital intensity are two potential mechanisms through which this reform affects labor income share.ConclusionIn summary, we establish a causal link between the reform of the phased reduction of the pension insurance contribution rate and enterprise labor income share. This suggests that continuing the reform could increase labor income share, but it necessitates enhanced collection and management of pension insurance contributions, along with differentiated policies based on regional and enterprise ownership characteristics.
Stress sources and symptoms: the role of gender in a Brazilian university medical school
Authors: Romeo Marina , Marques Antonio Luiz , Yepes-Baldó Montserrat , Boria-Reverter Sefa 
Published: January 2025

IntroductionThe main objective of this research was to identify the sources and symptoms of occupational stress among Brazilian university professors and examine the impact of gender on this relationship.MethodsA total of 81 university professors from a Brazilian Federal University Medical School answered a questionnaire that collected demographic and occupational data, lifestyle information, health issues, and stress symptoms originating from work and personal factors. Univariate statistics, Spearman correlation and the forgotten effects theory were used to analyze the data.ResultsParticipants experienced medium-high stress levels from individual factors and low stress levels from work-related factors. Common stress symptoms included fatigue and nervousness. There was a significant correlation between stress sources from work and individual factors, with different symptoms linked to each source. Gender moderated the relationship between work-related stress sources and symptoms and the forgotten effects theory revealed overlooked but significant cause-and-effect relationships.DiscussionUniversities should implement supportive measures and policies that consider the unique challenges faced by faculty, particularly related to gender. These initiatives can create a healthier and more productive work environment for professors and benefit both faculty members and students alike.
Mediating effects of social detachment in young and middle-aged stroke patients between stigma and ability to return to work
Authors: Dong Jinping , Ding Xueying , Wen Yating , Sun Shujie , Wu Jingliang , Wang Jianhua , Fan Yang , Hu Guojing , Xin Zhang , Li Jiayin , Sun Xiaoyan 
Published: January 2025

ObjectiveTo investigate the mediating effect of social isolation on the relationship between stigma and work ability in young and middle-aged stroke patients.MethodsFrom May 2022 to May 2024, a survey was conducted on young and middle-aged stroke patients visiting the neurology department of a tertiary hospital in Weifang. The survey utilized the General Information Questionnaire, the Rankin Scale, the General Isolation Scale, the Stigma Scale for Stroke Patients, and the Work Ability Scale.ResultsThe scores for work ability, social isolation, and stigma among young and middle-aged stroke patients were 44.23 ± 12.72, 46.27 ± 5.17, and 43.37 ± 4.48, respectively. There was a positive correlation between stigma and social isolation scores (r = 0.550, P &lt; 0.01), and a negative correlation between stigma and work ability scores (r = −0.371, P &lt; 0.01). Social isolation was negatively correlated with work ability (r = −0.418, P &lt; 0.01). Multiple linear stepwise regression analysis indicated that stroke type, duration of illness, mRS score, stigma, and social isolation are significant factors affecting work ability in young and middle-aged stroke patients. Social isolation significantly mediated the relationship between stigma and work ability, accounting for 21.66% of the total effect.ConclusionStigma and social isolation can directly predict the level of work ability in young and middle-aged stroke patients. Additionally, stigma can indirectly influence work ability through social isolation.
Hormone replacement therapy, menopausal age and lifestyle variables are associated with better cognitive performance at follow-up but not cognition over time in older-adult women irrespective of APOE4 carrier status and co-morbidities
Authors: Watermeyer Tamlyn J. , Gregory Sarah , Leetham Emmi , Udeh-Momoh Chinedu T. , Muniz-Terrera Graciela 
Published: January 2025

IntroductionThe impact of Hormone Replacement Therapy (HRT) on cognitive function in postmenopausal women remains a topic of considerable debate. Although estrogen's neuroprotective effects suggest potential cognitive benefits, empirical findings are mixed.MethodsThis study uses data from the Cognitive Function and Ageing Study Wales (CFAS Wales) cohort to explore the relationships between HRT use, age at menopause, APOE4 carrier status, lifestyle factors, comorbidities, and cognitive outcomes in older adult women. Two regression models were employed: one analyzing cognitive performance at follow-up and another examining changes in cognitive scores over time.ResultsResults indicate that while age, education, HRT use, age at menopause, alcohol consumption, and diet were associated with cognitive function at a single later time point, only age remained a significant predictor when modeling cognition over time.DiscussionThese findings suggest that while HRT, menopausal age and lifestyle factors may support cognitive stability, they do not necessarily predict cognitive decline in post-menopausal older women. A major limitation of the current work is the lack of detail regarding HRT use, such as formulation, timing and duration; caveats that future studies should address. The study underscores the need for longer follow-up periods, consideration of other female-specific risk factors, and more comprehensive lifestyle and health assessments to clarify the complex interplay between HRT use, reproductive history, lifestyle, comorbidities and cognitive aging in women.
Analysis Of The Implementation Of The ASEAN Political Security Community Framework In The Philippines In Counter Terrorism Efforts
Authors: Melinda Susan , Darmayadi Andrias 
Published: January 2025

This research aims to analyze the Philippines' failure in tackling terrorism based on the ASEAN Political-Security Community (APSC) Blueprint mechanism. This research uses a descriptive-qualitative approach to describe facts, characteristics of subjects and objects precisely, also uses data collection techniques through literature review by collecting secondary data. The results show that although the Philippines has ratified the ASEAN Convention on Counter Terrorism (ACCT) in 2010, it still relies on a militaristic approach in dealing with the Abu Sayyaf group in Mindanao, which is contrary to the APSC framework that emphasizes a comprehensive security approach. Moreover, based on adherence theory and constructivism paradigm, the Philippines shows its identity incompatibility with the ASEAN framework, as its priority on counterterrorism relies on a militaristic rather than comprehensive approach. Therefore, the case indicates ASEAN's ineffectiveness in ensuring the level of adherence of member states to implement the agreed regional counter-terrorism mechanism. Keywords — Adherence theory, APSC, Terrorism, the Philippines
Perancangan User interface Website Untuk Promosi Paw Paw Cafe Dengan Metode Design thinking
Authors: Erico Muhammad , Wicaksono Arif Ranu 
Published: January 2025

Penelitian ini bertujuan untuk merancang user interface (UI) website Paw Paw Cafe sebagai media promosi yang lebih modern dan professional dengan menggunakan metode design thinking. Industri kafe di Kota Surakarta, termasuk Paw Paw Cafe yang bertema animal cafe, mengalami pertumbuhan pesat. Namun promosi kafe masih terbatas menggunakan media sosial saja. Penelitian ini bertujuan untuk merancang user interface (UI) website Paw Paw Cafe sebagai media promosi yang lebih modern serta terkesan professional dan formal. Sehinga akan meningkatkan kepercayaan dan loyalitas pelanggannya. Dalam pengembangan UI website ini menggunakan metode design thinking terkenal dalam efektifitasnya karena mampu menggabungkan empati, kreativitas dan analisi dalam menyelesaikan permasalahan dalam pembuatan website. Metode design thinking yang meliputi tahapan empathize, define, ideate, prototype, dan test. Dalam pengujian UI website Paw Paw Cafe yang melibatkan 20 responden yang terdiri dari pengelola cafe dan pelanggan didapatakan hasil yang positif sekitar lebih dari 85% reponden menyatakan sudah Baik dalam aspek kecepatan akses, Kelengkapan informasi, kemudahan penggunaan navigasi, tampilan UI Website yang menarik dan UI Website Paw Paw Cafe dapat berfungsi dengan baik.
Self-Reported Burden and Health-Related Quality of Life in Acute Kidney Injury Survivors Compared to Patients with Advanced CKD
Authors: Huang Félix , Ethier Isabelle , Vaillant Isabelle , Silver Samuel A. , Côté Jean-Maxime 
Published: January 2025

Background:
Survivors of severe acute kidney injury (AKI) are at risk of increased morbidity. There are limited data of the quality of life (QOL) of patients having recently suffered from an AKI episode. The purpose of this study was to explore the health-related QOL of severe AKI survivors when compared to patients living with advanced chronic kidney disease (CKD).

Methods:
A prospective observational cohort study of severe AKI survivors who attended follow-up in a specialized post-AKI clinic was compared to a cohort of patients with advanced stage 4 or 5 CKD followed in a dedicated nephrology clinic. Self-reported health-related QOL was determined with the Treatment Burden Questionnaire (TBQ) and compared between both groups.

Results:
A total of 100 participants were included in the analysis. As opposed to CKD patients, AKI survivors were younger (median age: 63 [52-72] vs. 72 [62-79]), had lower comorbidities (median Charlson index: 5 [2-7] vs. 8 [6-9]) and higher eGFR at follow-up (median: 60 [40-82] vs. 15 [12-20]). The overall QOL reported by AKI survivors was not statistically different from advanced CKD patients (median TBQ score: 19.0 [6.5-43.8] vs. 25 [12.8-43.0]), p=0.45). The only domain where a significant difference was observed between the two cohorts was dietary restrictions (p=0.037). A negative correlation between age and TBQ score was observed (Spearman’s rank: -0.23 [p=0.02]), especially in CKD patients (-0.51 [p=0.001]), meaning older participants reported a lower impact on health-related QOL, and between eGFR and TBQ (-0.20 [p=0.049]), meaning patients with lower eGFR reported lower health-related QOL. No correlation was observed for hospital length of stay, burden of medication or follow-up duration since hospital discharge.

Conclusions:
This study showed that health-related QOL of patients recently discharged from a severe AKI episode is comparable to the low QOL reported by patients living with advanced CKD. How to integrate that information into clinical practice when offering post-AKI care requires further research.
Mapping of Research Themes on Environmental, Social, and Governance (ESG) Using Leximancer
Authors: Permatasari Ika , Permatasari Intan Kurnia , Laksono Bayu Rama , Putikadea Insyirah , Hidayat Rendra Arief 
Published: January 2025

This article presents a study using Leximancer (a text mining tool to visualize themes and concepts in text) to find any themes that still have a great opportunity to be studied further related to ESG. This study used the Scopus database and gathered 159 published articles from 2011 to 2020. The articles were selected based on the analysis of the abstract, the theory used, including the development of hypothesis (if any), and conclusions. Based on the main themes generated by Leximancer software, overall, the ‘social’ theme was the most dominant, while themes such as ‘investor’ and ‘sustainability’ were less dominant. This review reveals that the themes and concepts resulting from Leximancer’s content analysis have not been widely studied in the previous literature. Our study continues the previous literature review with a different scope and method. Leximancer offers a larger list of potentially useful keywords for further analysis and provides a visually appealing display of themes and concepts and their level of importance. The results of this review could be used as a basis for providing academic guidance in future ESG research.

Keywords: Leximancer, ESG, ESG themes, ESG concepts.
ВРЕДИТЕЛИ И БОЛЕЗНИ ПЛОДОВЫХ КУЛЬТУР И МЕРЫ БОРЬБЫ С НИМИ
Authors: Гусева Н.К. , Васильева Н.А. 
Published: January 2025

Плодовые культуры в Сибири являются одним их основных источников получения поливитаминной продукции с богатым биохимическим составом, растут и плодоносят в суровых климатических условиях (холодная и малоснежная зима, короткое, почти без осадков лето) и на бедных песчаных и суглинистых почвах. Большинство сортов плодовых культур многие годы считались устойчивыми к основным вредителям и болезням, что позволяло получать экологически чистый урожай без использования химических препаратов. В последние годы в Сибири на плодовых культурах появились вредители и болезни, наносящие не только вред многолетним насаждениям, но и приводящие к их гибели. Сегодня задачей сибирского садоводства является своевременное выявление вредителей и болезней плодовых культур, а также изучение методов борьбы, которые будут безопасны как для человека, так и для окружающей среды. В статье рассмотрены основные вредители и болезни плодовых культур, распространенные в Бурятии. Исследования проводились в любительских садах с 2014 г. и в саду лаборатории селекции и сортоизучения плодовых, ягодных и декоративных культур Бурятского НИИ сельского хозяйства. Объекты исследования – вредители и болезни семечковых и косточковых культур: яблоня, груша, слива, вишня. Исследования проведены в соответствии с методиками, применяемыми в садоводстве. По результатам многолетней работы изучено развитие вредителей и появление болезней, а также предложены биологические и химические препараты для борьбы с ними.
Fruit crops in Siberia are one of the main sources of multivitamin products with a rich biochemical composition. Such crops grow and bear under harsh climatic conditions (cold and dry winters, short, almost rainless summers) and on poor sandy and loamy soils. For many years, most varieties of fruit crops were considered resistant to major pests and diseases, which made it possible to obtain an environmentally friendly harvest without the use of chemicals. However, over recent years, pests and diseases have appeared on fruit crops in Siberia, causing damage to perennial plantings if control measures are not used in a timely manner. Today, an urgent problem of Siberian gardening is to identify pests and diseases of fruit crops in a timely manner, as well as to study of suppressing methods that will be safe for both humans and the environment.. The article deals with the main pests and diseases of fruit crops common for Buryatia. The research has been carried out in amateur gardens since 2014 and in the garden of the laboratory for selection and variety study of fruit, berries and ornamental crops of the Buryat Research Institute of Agriculture. Оbjects of research are pests and diseases of pome and stone fruit crops: apple trees, pear trees, plum trees, cherries. The research was carried out in accordance with the methods used in gardening. Based on the results of many years of work, the development of pests and the emergence of diseases have been studied, and practical methods of suppressing them have been developed (technological, biological, chemical).
ЯРОВАЯ РОЖЬ – ВАЖНЫЙ РЕЗЕРВ КОРМОВ В УСЛОВИЯХ ЗАСУХ
Authors: Мардваев Н.Б. , Шапсович С.Н. , Сандакова А.Е. , Надмитова Т.Н. 
Published: January 2025

Исследования проводили на территории землепользования СПК «Надежда» Джидинского района в сухостепной зоне Бурятии с 2016 по 2018 год. Схема опыта: два срока посева (20-21 и 29-30 апреля) и трех норм высева (2, 4 и 6,0 млн шт./га всхожих семян). Почва участка каштановая мучнисто-карбонатная легкого гранулометрического состава, преобладающая в сухостепных зонах Западного Забайкалья. За время проведения исследований метеорологические условия были засушливыми, когда суммы осадков были меньше средних многолетних значений, а суммы температур превышали средние многолетние. Изменение нормы высева с 2 до 4 млн/га не вело к существенному снижению полевой всхожести яровой ржи, а увеличение ее до 6 млн/га уже приводило к заметному ее снижению. Выживаемость растений яровой ржи к первому укосу, в среднем, по первому сроку посева – 68,8-75,0%, по второму сроку посева – 66,3-71,0%. Урожай за два укоса был всегда заметно больше при посеве повышенными нормами высева. Несмотря на засушливые условия, самые ранние посевы яровой ржи 20-21 апреля дали за два укоса урожай от 4,7 до 8,1, а более поздние посевы 29-30 апреля от 4,8 до 6,7 т/га зеленой массы. Прослеживалась зависимость между увеличением нормы высева с 2 до 4 и 6 млн шт. всхожих семян на 1 га и урожаями зеленой массы. Самые высокие в опыте урожаи получены в вариантах посева семян 20-21 апреля с нормой высева 6 млн всхожих семян на 1 га.
The research was carried out on the land use territory of the APC “Nadezhda” of the Dzhidinsky district, in the dry-steppe zone of Buryatia from 2016 to 2018. The scheme of the experiment was two sowing periods (April 20-21 and 29-30) and three seeding rates (2, 4 and 6.0 million pcs./ha of germinating seeds). The soil of the experimental plot is chestnut powderycarbonated of light granulometric composition, prevailing in the dry-steppe zones of Western Transbaikalia. During the research, meteorological conditions were arid, with total precipitation less than the average long-term indices, and the sums of temperatures exceeded the average long-term indices. The change in the seeding rate from 2 to 4 mln/ha did not lead to a significant decrease of the field germination of spring rye, while the increase to 6 mln/ha led to a noticeable decrease. The survival rate of spring rye plants by the first mowing on average by the first sowing period was 68.8–75.0%, by the second sowing period – 66.3-71.0%. The harvest for two mowing periods was always noticeably larger when sowing with increased seeding rates. Despite the arid conditions, the earliest spring rye crops sown on April 20-21 provided a yield from 4.7 to 8.1 in two mowing times, and later crops sown on April 29-30 - from 4.8 to 6.7 t/ha of fresh yield. There was a correlation between the increase in the seeding rate from 2 to 4 and 6 million pieces of germinating seeds per 1 ha and the yield of green mass. The highest yields during the experiment were obtained in the variants of sowing seeds on April 20-21 with a seeding rate of 6 million germinating seeds per 1 ha.
Studying the effect of Some Hematological Parameters on a cohort of female individuals afflicted with breast cancer in The National Cancer Center in AL- Najaf AL- Ashraf Province
Authors: Al-Mosawi Rabab Ali , Al-Azawi Ebtesam Mohsen 
Published: January 2025

The current study aims to shed light on the importance of blood standards in determining abnormality score values in studying the disease for patients with breast cancer (BC) and comparing them with healthy people.
The study included (50) women with breast cancer at different stages of the disease, with an average age ranging from (35 - 75) years. The study also included (25) healthy women with characteristics consistent with the previous group, and this group was classified as a control group.
Samples for this study were collected for the period (from the first of January to the end of June of 2023). They were collected from patients attending the National Educational Center for Oncology in Najaf Governorate and who were diagnosed clinically and laboratory. The results of blood tests showed average values of RBC, HB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW- CV, MPV, PCT, WBC, and LYM. The current results showed significant differences in some parameters below the significance level (P ≤0.05). While no significant differences appeared in some other parameters. This study demonstrated the importance of blood standards as useful markers and methods that help in distinguishing between individuals afflicted with breast cancer and individuals in a state of good health. people.
Patients with BC may have significant changes in various blood parameters. Blood parameters must be tested regularly for early diagnosis of the disease and the necessary follow-up is performed.