bluuebunny/crossref_metadata_2025_split huggingface dataset:
A randomized controlled trial of postoperative rehabilitation using digital healthcare system after rotator cuff repair
Authors: Shim Ga Yang , Kim Eun Hye , Baek Yun Jeong , Chang Won Kee , Kim Bo Ram , Oh Joo Han , Lee Jong In , Hwang Ji Hye , Lim Jae-Young 
Published: May 2023

AbstractA digital healthcare system based on augmented reality (AR) has promising uses for postoperative rehabilitation. We compare effectiveness of AR-based and conventional rehabilitation in patients after rotator cuff repair (RCR). This study randomly allocates 115 participants who underwent RCR to digital healthcare rehabilitation group (DR group) and conventional rehabilitation group (CR group). The DR group performs AR-based home exercises using UINCARE Home+, whereas the CR group performs brochure-based home exercises. The primary outcome is a change in the Simple Shoulder Test (SST) score between baseline and 12 weeks postoperatively. The secondary outcomes are the Disabilities of the Arm, Shoulder and Hand (DASH) score; Shoulder Pain And Disability Index (SPADI) score; EuroQoL 5-Dimension 5-Level (EQ5D5L) questionnaire score; pain; range of motion (ROM); muscle strength; and handgrip strength. The outcomes are measured at baseline, and at 6, 12, and 24 weeks postoperatively. The change in SST score between baseline and 12 weeks postoperatively is significantly greater in the DR group than in the CR group (p = 0.025). The SPADI, DASH, and EQ5D5L scores demonstrate group×time interactions (p = 0.001, = 0.04, and = 0.016, respectively). However, no significant differences over time are observed between the groups in terms of pain, ROM, muscle strength, and handgrip strength. The outcomes show significant improvement in both groups (all p < 0.001). No adverse events are reported during the interventions. AR-based rehabilitation shows better improvement in terms of shoulder function after RCR compared to conventional rehabilitation. Therefore, as an alternative to the conventional rehabilitation, the digital healthcare system is effective for postoperative rehabilitation.
Spin operator, Bell nonlocality and Tsirelson bound in quantum-gravity induced minimal-length quantum mechanics
Authors: Bosso Pasquale , Petruzziello Luciano , Wagner Fabian , Illuminati Fabrizio 
Published: May 2023

AbstractDifferent approaches to quantum gravity converge in predicting the existence of a minimal scale of length. This raises the fundamental question as to whether and how an intrinsic limit to spatial resolution can affect quantum mechanical observables associated to internal degrees of freedom. We answer this question in general terms by showing that the spin operator acquires a momentum-dependent contribution in quantum mechanics equipped with a minimal length. Among other consequences, this modification induces a form of quantum nonlocality stronger than the one arising in ordinary quantum mechanics. In particular, we show that violations of the Bell inequality can exceed the maximum value allowed in ordinary quantum mechanics, the so-called Tsirelson bound, by a positive-valued function of the momentum operator. We introduce possible experimental settings based on neutron interferometry and quantum contextuality, and we provide preliminary estimates on the values of the physical parameters needed for actual laboratory implementations.
Tunable spin and conductance in porphyrin-graphene nanoribbon hybrids
Authors: Gao Fei , Menchón Rodrigo E. , Garcia-Lekue Aran , Brandbyge Mads 
Published: May 2023

AbstractRecently, porphyrin units have been attached to graphene nanoribbons (Por-GNR) enabling a multitude of structures. Here we report first-principles calculations of two prototypical, experimentally feasible, Por-GNR hybrids, one of which displays a small band gap relevant as electrodes in devices. Embedding a Fe atom in the porphyrin causes spin-polarized ground state (S = 1). Using density functional theory and nonequilibrium Green’s function, we examine a 2-terminal setup involving a Fe-Por-GNR between small band gap, Por-GNR electrodes. The coupling between the Fe-d and GNR band states results in a Fano anti-resonance feature in the spin transport, making the conductance highly sensitive to the Fe spin state. We demonstrate how mechanical strain or chemical adsorption on the Fe give rise to spin-crossover to S = 2 and S = 0, directly reflected in the transmission. Our results provide a deep understanding which can open an avenue for carbon-based spintronics and chemical sensing.
Geometrical control of topological charge transfer in Shakti-Cairo colloidal ice
Authors: Rodríguez-Gallo Carolina , Ortiz-Ambriz Antonio , Nisoli Cristiano , Tierno Pietro 
Published: May 2023

AbstractLattice transformations that preserve the system topology, but not its geometry, are common in condensed matter systems. However, how geometric constrains influence the topological properties of the lattices is still unclear. Here we show that a geometric transformation between two mixed coordination lattices, from Shakti to Cairo in an artificial colloidal ice, leads to a breakdown of the ice rule in all but one specific geometry. We observe a transfer of topological charge among sublattices which can be controlled in sign and intensity, vanishing at the ice-rule point. These unusual topological effects are absent in magnetic spin ices and they are due to collective, non-local geometric frustration in the particle ice. By merging numerical simulations, theory and experiments, we demonstrate how the charge transfer occurs in the Cairo geometry. The broader implication of our results is that we demonstrate how geometric constraints can control the topological properties of a mesoscopic colloidal system.
Bio-inspired selective nodal decoupling for ultra-compliant interwoven lattices
Authors: Mistry Yash , Weeger Oliver , Morankar Swapnil , Shinde Mandar , Liu Siying , Chawla Nikhilesh , Chen Xiangfan , Penick Clint A. , Bhate Dhruv 
Published: May 2023

AbstractArchitected materials such as lattices are capable of demonstrating extraordinary mechanical performance. Lattices are often used for their stretch-dominated behavior, which gives them a high degree of stiffness at low-volume fractions. At the other end of the stiffness spectrum, bending-dominated lattices tend to be more compliant and are of interest for their energy absorption performance. Here, we report a class of ultra-compliant interwoven lattices that demonstrate up to an order of magnitude improvement in compliance over their traditional counterparts at similar volume fractions. This is achieved by selectively decoupling nodes and interweaving struts in bending-dominated lattices, inspired by observations of this structural principle in the lattice-like arrangement of the Venus flower basket sea sponge. By decoupling nodes in this manner, we demonstrate a simple and near-universal design strategy for modulating stiffness in lattice structures and achieve among the most compliant lattices reported in the literature.
Gliding tremors associated with the 26 second microseism in the Gulf of Guinea
Authors: Bruland Charlotte , Hadziioannou Celine 
Published: May 2023

AbstractA location in the Gulf of Guinea, which emits monochromatic seismic waves at 26-second period, seemingly continuously, was identified in the 1960s. However, the origin of these seismic waves remains enigmatic to date. Here we use three-component data from two seismic arrays in Africa, as well as additional seismic data compiled from around the world, to investigate the tremors. We identify frequency glides accompanying the previously known 26 s microseism which start at the same frequency and originate in the same, fixed location in the Gulf of Guinea. The stable characteristics of the tremors, their low frequency range, the implied large spatial scale, and the decades-long timescales where this phenomenon seems to have been active, all point towards a gap in our understanding of long period oceanic and volcanic signals. Since tremor is an important tool to monitor volcanoes, understanding this phenomenon may affect future forecasting of volcanic activity.
An epidemic model for the investigation of multi‐malware attack in wireless sensor network
Authors: Awasthi Shashank , Srivastava Pramod Kumar , Kumar Naresh , Ojha Rudra Pratap , Pandey Purnendu Shekhar , Singh Rajesh , Gehlot Anita , Priyadarshi Neeraj , Jain Rituraj , Bakare Yohannes Bekuma 
Published: May 2023

AbstractThe protection of wireless sensor networks (WSN) against malware attacks is crucial. The paper discusses the issue of malware attacks in WSN, which are commonly used for monitoring and surveillance in various applications. Due to resource constraints, sensor nodes in WSN are vulnerable to malware attacks, which can spread rapidly and paralyze the network. The development of new technologies such as IoT, Industry 4.0 has increased the importance of WSN, and it has become essential to address the challenges posed by the resource‐constrained nature of sensor nodes and security concerns. In this paper, a model is considered with two exposed states to investigate the behaviour of malware spreading in WSN, and a SE1E2IR (Susceptible—Exposed State 1 ‐ Exposed State 2 ‐ Infectious—Recovered) model is proposed. The model is formulated as a system of differential equations, and its equilibrium and stability are examined. The basic reproduction number (R0) is also calculated as a key parameter that characterizes the spread of malware in the network. This parameter helps to identify the conditions under which the network will remain malware‐free or when it will experience an outbreak of malware. The proposed model provides a mechanism for the earlier detection of malware occurrences in WSN, and also discusses the effect of connectivity and coverages on the propagation of malware in the network. The paper also includes a comparative study of the proposed model with existing models; extensive theoretical study and computation analysis are performed to validate the proposed model.
Selbstmanagement beim Lymphödem
Authors: Niemann Heike , Helmbrecht Susanne 
Published: May 2023

SummarySelbstmanagement beim Lymphödem ohne ausreichenden und fachlich richtigen Input von außen kann nicht funktionieren. Denn falsche Vorstellungen oder falsche „Hinweise“ aus sozialen Medien führen häufig zum Aufgeben, da keine ausreichenden Erfolge erzielt werden. Doch was gehört zum Selbstmanagement?
Venöse Gefäßerkrankungen
Authors: Schmid Eva C. 
Published: May 2023

SummaryDer überwiegende Teil der erwachsenen Bevölkerung, nämlich etwa 90 % der zwischen 18- und 79-Jährigen, weist venöse Veränderungen auf. Manche Veränderungen im Venensystem haben nur kosmetische Relevanz, andere können jedoch einen chronischen Verlauf mit weitreichenden Folgen nehmen. Von großer Bedeutung ist die chronisch-venöse Insuffizienz (CVI), eine chronische venöse Hypertonie der Beine, die mit Venen- und Hautveränderung einhergeht. Das Ulcus cruris venosum stellt die schwerste Form dieser Erkrankung dar.
Cholesterinsenker im Wandel
Authors: Wendland Matthias 
Published: May 2023

Summary80 % des Cholesterins produziert der Körper selbst in der Leber, unter anderem als Baustein von Gallensäuren, Vitamin D, Zellmembranen und Hormonen. Durch übermäßige Aufnahme im Rahmen moderner Ernährung kann der Spiegel jedoch unkontrolliert ansteigen und zu Arteriosklerose führen. Klassische und gebräuchlichste Medikamente sind die Statine (CSE-Hemmer), Cholesterin-Resorptionshemmer (Ezetimib) und Ionenaustauscherharze (Colestyramin). Allerdings kamen in den letzten Jahren weitere interessante Wirkstoffe hinzu, darunter ACL-Inhibitoren (Bempedoinsäure), Antikörper (Alirocumab, Evolocumab) und RNA-Therapeutika (Inclisiran). Neben gesunder Ernährung und Lebensweise tragen auch Phytosterine, Vitamin D und Coenzym Q10 (mildert Statinnebenwirkungen) zu einer Verbesserung bei.
Pflanzliche Hilfe für das kleine Becken
Authors: Wanitschek Anne 
Published: May 2023

SummaryEine, meist vegetativ bedingte, Minderdurchblutung des kleinen Beckens der Frau kann zu Beschwerden wie Libidomangel, Menstruationsstörungen, Vaginaltrockenheit und Unfruchtbarkeit führen. Dies zeigt sich iridologisch unter anderem mit dunklem Hautring, Lakunen und charakteristischen Abdunkelungen. Heilpflanzen unterstützen in unterschiedlichen Zubereitungen die Beckendurchblutung, Blutbildung, Parasympathikus- und Uterusaktivität, Entspannung, Lust, Östrogen- und Progesteronproduktion. Im vorgestellten Fall wurden Fruchtbarkeitsstörungen in Verbindung mit Stressbeschwerden und Hypothyreose mit Phytotherapeutika und Probiotika erfolgreich und bis zum erfüllten Kinderwunsch behandelt.
Die Perspektive von Stakeholdern auf Nutzende von Pflegerobotik an
der Intersektion Alter und Geschlecht – Ergebnisse einer qualitativen
Analyse
Authors: Weßel Merle , Ellerich-Groppe Niklas , Schweda Mark , Koppelin Frauke 
Published: May 2023

ZusammenfassungPflegerobotik wird in Politik und Wirtschaft als vielversprechende Lösung
für den anhaltenden Fachkräftemangel sowie den steigenden
Pflegebedarf gesehen. Studien zeigen jedoch, dass die potenziell Nutzenden sich
wenig von solchen Technologien angesprochen fühlen und
Technikentwickelnde kaum Kenntnis von Bedarfen und Bedürfnissen der
potentiell Nutzenden haben. Vor diesem Hintergrund untersucht der vorliegende
Beitrag auf der Grundlage von 16 qualitativen Stakeholderinterviews mit
Expert*innen aus der Technikentwicklung, Technikvermarktung und
Pflege(wissenschaft) explorativ, welche Annahmen und Erwartungen
bezüglich Alter und Geschlecht der Nutzenden in diesem Bereich von
Bedeutung sind. Dabei werden drei unterschiedliche Perspektiven
herausgearbeitet: 1) die Rolle von Alter und Geschlecht für die
Entwicklung und den Einsatz von Pflegerobotik wird wahrgenommen, 2) die Relevanz
alternativer Kategorien wie Bildung, Kultur oder Krankheit wird benannt und 3)
sozialen Kategorien wird keinerlei Bedeutung zugeschrieben. Die Ergebnisse
werden im Licht des Diskurses über Diversität in der
Pflegerobotik diskutiert und es werden Schlussfolgerungen für eine
nutzendenorientierte, diversitätssensible Technikentwicklung und
-implementierung gezogen.
Walking exercise through smartphone application plus branched-chain amino acid supplementation benefits skeletal muscle mass and strength in liver cirrhosis: A prospective control trial
Authors: Xiang Qian , Xiong Jing , Zhao Zhi jing , Zhou Ting , Wu Jun , Chen Xia 
Published: May 2023

Abstract
Introduction and objectives Whether a combination of exercise and
branched-chain amino acid (BCAA) supplementation was more beneficial than those given alone in
sarcopenia related to liver cirrhosis (LC) is unknown. Widely used smartphone applications
provide continuous and easily expandable management of chronic liver disease (CLD). This study
is to investigate the effects of unsupervised walking exercise using WeChat combined with BCAA
supplementation on skeletal muscle mass and strength in LC.
Materials and Methods The 127 LC patients of Child–Pugh A/B were
assigned to group A (BCAA supplements, n=42), group B (walking exercise, n=43) and group C
(walking exercise plus BCAA supplements, n=42). Laboratory data, average daily steps, serum
BCAA, skeletal muscle mass index (SMI) and grip strength were analyzed pre- and 3 months after
interventions.
Results Of the 124 patients who completed interventions, albumin
and daily steps were significantly increased in all groups (p=0.0001). Post-intervention BCAA were significantly elevated in group A (A vs B,
p=0.001) and C (C vs B, p=0.012;).
While post-intervention daily steps in group B (B vs A, p=0.0001)
and C (C vs A, p=0.0001) were higher. Grip strength (C vs A, p=0.020; C vs B, p=0.036) and SMI (C vs A,
p=0.035; C vs B, p=0.012) were
increased in group C. Prevalence of sarcopenia was significantly decreased in group C (p=0.015).
Conclusions A combination of unsupervised walking exercise using
smartphone applications and BCAA supplementation might be an effective and safe treatment for
cirrhosis patients with Child–Pugh A/B to improve skeletal muscle mass and strength or to
prevent progress of sarcopenia.
EUS-guided gastroenterostomy vs. surgical gastrojejunostomy and enteral stenting for malignant gastric outlet obstruction: a meta-analysis
Authors: Miller Corey , Benchaya Joshua A , Martel Myriam , Barkun Alan , Wyse Jonathan M , Ferri Lorenzo , Chen Yen-I 
Published: May 2023

Abstract
Background and study aims Malignant gastric outlet obstruction (MGOO) is traditionally treated with surgical gastrojejunostomy (SGJ), which is effective but associated with high rates of morbidity, or endoscopic stenting (ES), which is less invasive but associated with significant risk of stent dysfunction and need for reintervention. Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) provides a robust bypass without the invasiveness of surgery.
Methods We performed a systematic review and meta-analysis comparing EUS-GE to SGJ and ES for MGOO. Electronic databases were searched from inception through February 2022. A meta-analysis was performed with results reported as odds ratios (ORs) with 95% confidence intervals (CIs) using random effects models. Primary outcomes included clinical success without recurrent GOO and adverse events (AEs).
Results Sixteen studies involving 1541 patients were included.
EUS-GE was associated with higher clinical success without recurrent GOO compared to ES or SGJ
[OR 2.60, 95% CI1.58–4.28] and compared to ES alone [OR 5.08, 95% CI 3.42–7.55], but yielded
no significant difference compared to SGJ alone [OR 1.94, 95% CI 0.97–3.88]. AE rates were
significantly lower for EUS-GE compared to ES or SGJ grouped together [OR 0.34, 95% CI
0.20–0.58], or SGJ alone [OR 0.17, 95% CI 0.10–0.30] but were not significant different versus
ES alone [OR 0.57, 95% CI 0.29–1.14].
Conclusions EUS-GE is the most successful approach to treating MGOO, exhibiting a lower risk of recurrent obstruction compared to ES, and fewer AEs compared to SGJ.
Enabling Real-World Data to Accelerate the Development of Innovative Cancer Biomarkers
Authors: Yeh Chen 
Published: May 2023

AbstractThe molecular diagnostics industry has historically relied on sanitized clinical trials and commoditized data sources to inform its biomarker discovery and validation process—an under-substantiated approach that was ultra-expensive, resource-consuming and did not reflect how representative a new biomarker would be in broader patient populations. In an effort to gain more accurate insight into the patient experience and bring innovative biomarkers to market more efficiently and accurately, the industry is now expanding into extended real-world data. To access the needed breadth and depth of patient-centric data, diagnostic companies must collaborate with a healthcare data analytics partner that has three key assets: (i) a broad and deep megadata with metadata, (ii) a data-rich provider network, and (iii) an outcomes-improvement engine to support the next generation of molecular diagnostics (Dx) and therapeutics (Rx) development.
Peroneal Nerve Repair with Cross-Bridge Ladder Technique: Parallel End-to-Side Neurorrhaphies
Authors: Ammanuel Simon , Burkett Daniel , Kim Jason J. , Bond Evalina S. , Hanna Amgad S. 
Published: May 2023

Abstract
Background Multiple nerve transfer techniques are used to treat patients with nerve injuries when a primary repair is not possible. These techniques are categorized to end-to-end, end-to-side, and side-to-side neurorrhaphy. Our study aims to explore the utility of the cross-bridge ladder technique (H-shaped), which has shown promising results in animal models and probably underutilized clinically.
Methods Four patients with significant loss of ankle dorsiflexion were seen in the clinic and underwent evaluation, including electrodiagnostic studies. A cross-bridge ladder repair technique was used between the tibial nerve as the donor and the common peroneal nerve as the recipient via one or two nerve grafts coapted in parallel with end-to-side neurorrhaphies. Dorsiflexion strength was measured preoperatively using the Medical Research Council (MRC) grading system and at each postoperative follow-up appointment.
Results All four patients had suffered persistent and severe foot drop (MRC of 0) following trauma that had occurred between 6 and 15 months preoperatively. Three of the four patients improved to an MRC of 2 several months postoperatively. The last patient had an immediate improvement to an MRC of 2 by his first month and had a complete recovery of ankle dorsiflexion within 4 months from surgery.
Conclusion We demonstrate the utility and clinical outcomes of the cross-bridge ladder technique in patients with persistent and prolonged foot drop following trauma. Both early and late recovery were seen while all patients regained motor function, with some patients continuing to improve up to the most recent follow-up.IRB Approval: Obtained 2013–1411-CP005
Multisystem Inflammatory Syndrome in Children Associated with COVID-19 Infection: Clinical Presentation and Outcome
Authors: Agrawal Ritesh Kumar , Sharma Rewati , Mishra Arpita , Singh Ashok , Narayan Raghvendra , Mishra Om Prakash 
Published: May 2023

Abstract
Objective In the midst of the COVID-19 pandemic, many children presenting with persistent fever, rashes, conjunctivitis, abdominal pain, respiratory distress, and shock were reported and diagnosed with multisystem inflammatory syndrome in children (MIS-C). The aim of the study was to observe the clinical presentation and outcome of MIS-C treated at a tertiary care hospital.
Methods Eighteen children, aged 24 days to 18 years, with suspected MIS-C were admitted. Their clinical presentation, laboratory parameters, radiological investigations, management, and outcomes were recorded.
Results Median age was 8 years (interquartile range [IQR]: 0.5, 14), and the male-to-female ratio was 1:1. Fever, tachycardia, respiratory distress, hypotension, and seizures with altered sensorium were present in 94.4, 88.8, 83.3, 44.4, and 44.4% of the cases, respectively. Median erythrocyte sedimentation rate, C-reactive protein, serum ferritin, and d-Dimer levels were 21 mm/h, 151 mg/L (1,14.2, 319), 1,091 µg/L (737.4, 1,456), and 3,094 ng/mL (990, 4,300), respectively. Methylprednisolone was given to all patients. Low molecular weight heparin and intravenous immunoglobulin (IVIG) were instituted in 83.3 and 38.8% cases, respectively. Seventeen patients (94.4%) required oxygen therapy and 44.4% needed mechanical ventilation. Fourteen patients (77.7%) recovered completely and four cases (22.2%) expired during the hospital stay. The need for ventilation and the presence of shock adversely affected the outcome.
Conclusion Chief clinical presentations in the patients of MIS-C were fever, respiratory distress, hypotension, and altered sensorium. Among admitted patients, 87.8% cases were managed successfully by systemic corticosteroids with or without IVIG. Need for mechanical ventilation, shock, and central nervous system symptoms at admission appear to be important factors that can lead to mortality.