bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desempenho e repetibilidade de características de frutos de acessos de Physalis angulata L..
Authors: Toupe Arsene Mariano Sebastien , Lima Jefferson Souza , Souza Ian de Oliveira , de Souza Erison Martins , Passos Adriana Rodrigues , Silva Luiz Cláudio Costa 
Published: June 2023

Abstract
The Physalis angulata L. species, better known in Brazil as camapu, is most found in the northern regions of the country. It is used for human consumption, in medicine and as an ornamental plant. Because of its potential economic and nutritional value, studies have carried out to known the genetic variability of fruit traits. Repeatability is the fraction of phenotypic variation that is due to permanent genetic and environmental factors. The estimation of repeatability coefficient allows breeders to estimate the ideal number of measurements for a trait. This work aims to evaluate the performance of P. angulata accessions and to estimate the coefficients of repeatability and minimum number of repetitions for fruit characteristics, in two environments and two seasons. The present work was conducted at the Horto Florestal Experimental Unity of Universidade Estadual de Feira de Santana, using seven accessions of P. angulata from the Germplasm Collection of LAGEM/UEFS. Four experiments were conducted, two in the experimental field and two in the greenhouse, in an entirely randomized design with 24 replicates, using five accessions in the first two experiments, and six accessions in the last two in each environment, totaling 120 and 144 experimental units, respectively. The characteristics number of fruits per plant (NFP), soluble solids content (SSC), longitudinal diameter (LFD) and transversal diameter (TFD) of the fruits, and average fruit mass (AFM) were evaluated. Data were submitted to analysis of variance (ANOVA) and estimates of repeatability coefficients were obtained by ANOVA, principal components (PC), and structural analysis (SA) methods. There was significant variance among accessions for the characteristics LFD, TFD, AFM and SSC in the experimental field, and for TFD, LFD NFP in the greenhouse. Heritability ranged from 61.63–91.91% in both environments. PC showed the highest estimates of repeatability coefficient. The repeatability and determination coefficients by PC analysis ranged from TFD (r = 0.51; R2 = 96.19%) to SSC (r = 0.72; R2 = 98.47) in the field, and from NFP (r = 0.40; R2 = 93.92%) to LFD (r = 0.51; R2 = 79.38%) in the greenhouse. Twenty measurements can achieve 95% and 90% reliability for experimental field and greenhouse experiments, respectively, for the evaluated traits.
Fourier-domain beamforming for Full Matrix Capture Data with Circular Statistics Vector Weighting in Nondestructive Testing
Authors: Chen Yao , Ma Xiaoxiao , Xiong Zhenghui , Chen Junchao , Kang Yaxuan , Lu Chao 
Published: June 2023

Abstract
Total focusing method (TFM) based on full-matrix capture (FMC) is widely used in the field of nondestructive testing due to its high resolution and high signal-to-noise ratio. In order to solve the problems of the slow speed of traditional time-domain total focusing imaging and poor imaging quality, this paper proposes a total focusing imaging method weighted by circular statistics vector (CSV) in the Fourier domain (FD). Firstly, the cosine and sinusoidal components of the instantaneous phase in the undelayed RF signal are extracted, and the coherence factor is established according to the cosine and sinusoidal components in the FD domain. Finally, the total focusing image in the FD domain is weighted. The complexity calculation shows that CSV-weighted imaging in the FD domain has a higher imaging speed than delay-and-sum (DAS) imaging. The DAS total focusing imaging algorithm, FD domain total focusing imaging algorithm, and FD domain CSV weighted imaging algorithm are used to verify the hole and crack defects in brass test blocks, aluminum test blocks, and steel test blocks. The experimental results show that the proposed FD domain CSV weighted imaging map generally shows higher resolution and signal-to-noise ratio, and the algorithm has higher robustness. Also, it has revealed a low computational load.
Associations Between Improvements in Psychological Variables and Subsequent Sick Leave Among Persons Receiving a Multimodal Intervention for Exhaustion Disorder
Authors: de Leur Jakob Clason van , Buhrman Monica , Wallby Kajsa , Karlström Amanda , Johansson Fred 
Published: June 2023

Abstract

Background: The incidence of sick leave due to stress-related disorders such as exhaustion disorder (ED) is high in many economically developed countries. Meanwhile, knowledge about facilitating return to work during clinical interventions for ED patients is still limited. The current study aimed to investigate if improvements in exhaustion symptoms, insomnia, perfectionistic behaviors, psychological flexibility, and perceived work ability during treatment of ED were associated with subsequent sick leave in the year following treatment.
Methods: Using a cohort of 880 ED patients who had participated in a multimodal intervention based on Cognitive Behavior Therapy, we estimated the association between one standard deviation (SD) improvement in treatment-related variables and the rate of net days of sick leave one-year following treatment.
Results: Our results showed that improvements in all treatment-related variables were associated with lower sick leave rates one year following treatment. Improvements in exhaustion symptoms (rate ratio (RR): 0.70 [95% CI 0.66; 0.75]) and self-perceived work ability (RR 0.56 [95% CI 0.50; 0.63]) showed the largest associations to subsequent sick leave.
Conclusions:These findings suggest that interventions that focus on exhaustion symptoms, insomnia, perfectionistic behaviors, psychological flexibility, and perceived work ability during treatment can have meaningful impacts on ED patients' ability to return to work.
Trial registration: Clinicaltrials.gov (Identifier: NCT03360136)
An ocean of stratospheric aerosols after the Hunga Tonga– Hunga Haʻapai volcanic eruption
Authors: Vernier Hazel 
Published: June 2023

Abstract
Volcanic eruptions are key drivers of the natural variability of the Earth’s Climate system. The sulfate aerosols produced by major volcanic events can last for several years and reduce surface temperatures while warming the stratosphere1. However, this “classic” view is now challenged by the January 15th, 2022, Hunga Tonga Hunga Ha’apai submarine eruption. For the first time in the satellite era, a volcano injected material up to the mesosphere2 leading to an increase in the global stratospheric water vapor burden by 10% from seawater injected3. However, no information is available about the chemical properties of the plume. Herein, we show a detailed analysis of the chemical composition of the HTHH plume through a new balloon-based sampling technique. The ion chromatographic analysis of the sampled aerosols shows the presence of sea salts as opposed to a pure sulfate plume alone. The chemical analysis thereby revealed that the HTHH is more complex than initially thought and may explain the unexpected aerosol burden created by this eruption relative to the expected sulfate aerosol produced from the modest 0.6 Tg SO2 injected. These results challenge the current models that simulate the climate impacts of volcanoes.
Coronary tortuosity: a new gender related risk factor?
Authors: Donna Carlo Di , Ricci Francesca , Rellini Carlotta , Pugliese Luca , De Stasio Vincenzo , D'Errico Francesca , Madonna Matteo , Patanè Alberto , Garaci Francesco , Floris Roberto , Chiocchi Marcello 
Published: June 2023

Abstract
Gender differences in cardiovascular disease represent a great challenge for cardiology. Coronary vessel tortuosity is common anatomical feature that shows significant prevalence in women.Tortuosity modifies vessels hemodinamyc; coronary tortuosity is related to helical flow which results in a reduction of myocardial perfusion pressure and in increase of shear stress and microcirculatory resistance. 149 patients (78 males;71 females), with low to intermediate cardiovascular risk and no previous history of CAD, who underwent coronary CT scan were included in this retrospective study. All patients who underwent CCT were admitted to our institution with no cardiac symptoms and low or intermediate cardiovascular risk, according to ESC guidelines. It can be observed that there is a positive, strong and statistically significant relationship between NYHA and all the other variable. In our study we demostrate correlation between coronary tortuosity, diastolic disfunction and symptoms.
Co-enrichment of cancer-associated bacterial taxa is correlated with immune cell infiltrates in esophageal tumor tissue
Authors: Greathouse KL , Stone JK , Vargas AJ , Choudhury A , Padgett N , White JR , Jung A , Harris CC 
Published: June 2023

Abstract
Esophageal carcinoma (ESCA) is a leading cause of cancer-related death worldwide, and Barrett’s esophagus (BE) is a strong risk factor along with smoking. Smoking is well-known to induce microbial dysbiosis and we asked if BE and esophageal microbiomes had shared microbial alterations that could provide novel biomarkers. We extracted DNA from BE tissues (n=5) and tumors of 158 patients in the NCI-MD case control study and sequenced the 16S rRNA gene (V3-4), with TCGA ESCA RNAseq (n = 173) and WGS (n = 139) non-human reads used as validation. We identified four taxa, Campylobacter, Prevotella, Streptococcus, and Fusobacterium as highly enriched in esophageal cancer across all cohorts. Using SparCC, we discovered that Fusobacteriumand Prevotella were also co-enriched across all cohorts. We then analyzed immune cell infiltration to determine if these dysbiotic taxa were associated with immune signatures. Using xCell to obtain predicted immune infiltrates, we identified a depletion of megakaryocyte-erythroid progenitor (MEP) cells in tumors with presence of any of the four taxa, along withenrichment of platelets in tumors with Campylobactor or Fusobacterium. Taken together, our results suggest that intratumoral presence of these co-occurring bacterial genera may confer tumor promoting immune alternations that allow disease progression in esophageal cancer.
Twin Delayed Stochastic Actor-Critic
Authors: Asadolahi Mohammad , Sharifi Arash , Banirostam Touraj 
Published: June 2023

Abstract
In both discrete and continuous domains, model-free reinforcement learning algorithms have been successfully applied to the vast majority of reinforcement learning problems and are the main solution to real world problems. In reinforcement learning problems with continuous action space, state-of-the-art algorithms are extremely sample-inefficient and need lots of training interactions to become proficient, which could be catastrophically expensive and infeasible in real-world problems. So far, frontier algorithms have not used well-defined methods to explore the decision space. Exploring new behaviors is a prerequisite to look for optimal policies. All of the leading algorithms in the field leverage a blind form of exploration added to agent decisions to search for better policies. Such solutions fail to mindfully explore the environment, disrupting the learning process. This makes these algorithms very prone to failing in specific domains. In this research, a novel stochastic Off-Policy Actor-Critic algorithm, TDS for short, is presented. Combining the policy gradient theorem with the deterministic policy gradient, the TDS algorithm can learn how to mindfully explore the environment. The proposed update method enables TDS to learn how to modify the decision stochasticity bonds for each state and action. This is done according to gradients information derived from learning feedbacks. Evaluations in MuJoCo and Box2D tasks show faster convergence or outperform the state-of-the-art algorithms including TD3, SAC, and DDPG in every environment tested.
Development of a novel protocol for enhanced tomato callus formation and growth through the use of medicinal Plant extracts
Authors: sohrabi omid , Hatamzadeh Abbdollah , Ghasemnezhad Azim , Samizadeh Habibollah , Erfani-moghadam Vahid 
Published: June 2023

Abstract
Medicinal plants and their derivatives have been used for centuries in various sectors beyond treatment and nutrition. However, the use of toxic chemicals such as pesticides, fungicides, and herbicides has led to environmental pollution, necessitating the search for eco-friendly alternatives. Medicinal plants and their compounds offer a promising solution due to their naturalness and biodegradability. An in-vitro experiment was conducted at Gorgan University in 2022 to test the impact of six medicinal plant extracts on tomato growth and callus induction. Two concentrations of 50 and 100 mg/L were added to the Murashige and Skoog (MS) medium culture. Results showed a 100% increase in germination speed and an increasing trend in stem length (SL), with the 50 mg/L Juniperus sabina treatment yielding the highest amount. The amount of callus growth (CG) and weight (CW) increased by 50% and over 200%, respectively, with the Taraxacum officinale 100 and Conocarpus erectus 50 mg/L treatments producing the best results. More than 90% callus formation was observed compared to the control. Biochemical analysis revealed that the extracts were rich in phenolic compounds (348 mg/g of total phenol), flavonoids (162 mg/g), antioxidants (61%), and auxin. Antioxidant and plant growth regulators (PGR) content and the stimulation of the plant's defense system likely contributed to the results. Plant extracts also affected the biochemical content of calluses, with the exception of total phenol. Using plant extracts to increase growth and reduce time for callus induction is recommended in tomato tissue culture. However, optimal concentration and combination of medicinal plant extracts for different plant species and growth conditions require further research.
Vitamin D deficiency and bone density in children with celiac disease in southern Iran: An academic tertiary referral center's experience
Authors: Honar Naser , davoodi marzieh , Azizi Mehdi , Saki Forough 
Published: June 2023

Abstract
Objectives
Celiac disease is not limited to the digestive tract. Patients are at high risk for secondary osteoporosis, rendering the monitoring of bone density critical. We aimed to examine vitamin D deficiency and bone density in children with celiac disease.
Methods
This prospective cross-sectional study was conducted in 2018–2019 in the Fars province of Iran. The study population included children with celiac disease referred to Imam Reza Clinic or Namazi Hospital within the study period. Patients were examined for vitamin D deficiency and bone density levels.
Results
The present study included 10 (43.5%) boys and 13 girls (56.5%) with celiac disease. Only two patients were under vitamin D supplementation (8.7%). Growth disorders were the most common reason for referral (78%). Celiac disease in most children was associated with vitamin D, calcium, and parathyroid hormone enzyme activity disorders. Increasing age was associated with vitamin D deficiency. The lumbar and femoral bone density were associated with the puberty stage but not the age or gender.
Conclusions
Considering that the prevalence of osteoporosis and osteopenia is very high in celiac disease patients, a proper screening program should be devised to reduce the injuries caused by undiagnosed bone disorders.
On the Investigation of Interacting Fault Movement in a Viscoelastic Structure
Authors: Kundu Piu , Negi Anil 
Published: June 2023

Abstract
Investigations of the effects of ground deformation due to fault movement on surface and subsurface engineering structures
are important owing to their direct impact on the reduction of earthquake damage. This ground deformation has a great impact on displacement and stress-strain accumulation due to fault movement. In this study, a theoretical model of aseismically creeping, interacting, inclined, buried and strike-slip fault has been considered and the fault model located in a visco-elastic half-space of Maxwell medium. The analytical solution of displacement, stress and strain components in the absence of fault movement and due to interaction between the faults has been obtained by using the correspondence principle in terms of Mittag-Leffler function and Green's function. The obtained results has been studied graphically which may helps us to study earthquake prediction program.
Visit-to-visit blood pressure variability and clinical events in older patients receiving home medical care: The OHCARE study
Authors: Koujiya Eriko , Kabayama Mai , Yamamoto Mariko , Higami Yoko , Kodama Kana , Mukai Sakino , Yano Tomoko , Nako Yumiko , Murakami Naoko , Fukata Yuka , Godai Kayo , Nakamura Toshinori , Hirotani Atsushi , Fukuda Toshio , Tamatani Michio , Okuda Yoshinari , Ikushima Masashi , Baba Yoshichika , Nagano Masahiro , Takeya Yasushi , Rakugi Hiromi , Kamide Kei 
Published: June 2023

Abstract
Background
In recent years, the management of blood pressure (BP) variability and mean BP levels have become more important for hypertensive patients. We investigated the association of visit-to-visit variability (VVV) of BP with clinical events in older patients (about 85 years old) receiving home medical care.
Methods
We included patients who were followed up as part of the Osaka Home CAre Registry (OHCARE) study. OHCARE was a prospective cohort study that targeted older patients receiving home medical care in Japan. We included patients (n = 103) that fulfilled the following inclusion criteria: aged 65 years or older; BP measurements performed on at least three occasions before the baseline date (median 4.78 occasions); BP measurement interval of 16 ± 13 days (median ± 1 standard deviation [SD]). We used SD and coefficient of variation (CV) of systolic blood pressure (SBP) measured at baseline as the VVV of BP. Main outcomes were clinical events including hospitalizations, falling, and death during follow-up.
Results
Regarding the relationship between VVV and clinical events, the rate of hospitalization was significantly higher in the group with the largest SD of SBP than in the group with the smallest. Furthermore, multivariate analysis showed that SD and CV of SBP had independent positive associations with hospitalization.
Conclusions
In older patients requiring home medical care, a higher VVV in SBP may be related to the occurrence of events leading to hospitalizations; thus, our findings suggest that it could be used as a predictive marker.
The Effect of an Adapted Digital Mental Health Intervention for Sickle Cell Disease on Engagement: A Pilot Randomized Controlled Trial
Authors: Parchuri Ektha , Nardo Emily , O'Brien Julia , Crosby Lori , Porter Jerlym , Palermo Tonya , Nikolajski Cara E , Treadwell Marsha , Hillery Cheryl , Szigethy Eva , Jonassaint Charles 
Published: June 2023

Abstract
INTRODUCTION: Despite promising outcomes, lack of engagement and poor adherence are barriers to treating mental health using digital CBT, particularly in minority groups. After conducting guided focus groups, a current mental health app was adapted to be more inclusive for minorities living with SCD.
METHODS: Patients between the ages of 16–35 with SCD who reported experiencing anxiety or depression symptoms were eligible for this study. Once enrolled, participants were randomly assigned to receive one of two versions of a mental health app 1) the current version designed for the general population and 2) the adapted version. Baseline measures for depression, anxiety, pain and self-efficacy were completed at the start of the study and again at postintervention (minimum 4 weeks).
RESULTS: Compared to baseline, pain (p = 0.03), self-efficacy (p = 0.007) and depression symptoms (p = 0.016) improved for the group that received the adapted app. Regardless of group assignment, a positive relationship (r = 0.47) was shown between app engagement and a change in depression symptoms (p = 0.042).
DISCUSSION: Target enrollment for this study sought to enroll 40 participants. However, after difficulties locating qualified participants, enrollment criteria were adjusted to expand the population pool. Regardless of these efforts, the sample size for this study was still smaller than anticipated (n = 21). Additionally, irrespective of group approximately 40% of participants did not engage with the app. However, despite a small sample size and poor engagement, participants in the intervention group displayed better outcomes and showed trends for greater app interaction.
CONCLUSION: These promising results should encourage future researchers to continue exploring ideal adaptations for implementing digital CBT in minority populations. Future studies should also consider implementing post-intervention surveys to help identify common factors relating to a lack of engagement.
Test-retest reliability and practice effect of the Test of Visual Perceptual Skills-4th Edition for individuals with schizophrenia
Authors: Chiu En-Chi , Lee Shu-Chun 
Published: June 2023

Abstract
Background
The Test of Visual Perceptual Skills-4th Edition (TVPS-4) is widely used for repeated measures of visual perception. This study aims to examine the test-retest reliability and practice effect of the TVPS-4 in individuals with schizophrenia receiving care in community psychiatric rehabilitation facilities.
Methods
A repeated assessment design was employed, involving 80 participants. Test-retest reliability was evaluated using the intraclass correlation coefficient (ICC). Minimal detectable change (MDC) values were calculated at 95%, 90%, and 80% confidence levels. The MDC% was determined based on the MDC with 95% certainty. Cohen's d effect sizes and paired t-tests were utilized to assess the practice effect.
Results
The ICCs of the overall scale and the seven subscales of the TVPS-4 were 0.93 and 0.59–0.84, respectively. The MDC95 (MDC%), MDC90, and MDC80 ranged from 4.7–16.3 (13.2–34.8%), 3.9–13.6, and 3.1–10.6, respectively. Cohen’s ds were 0.06–0.26 and paired t-test showed significant differences in scores of the overall scale and the four subscales (p < 0.05).
Conclusion
The TVPS-4 has acceptable test-retest reliability and trivial to small practice effect, and the MDCs at different confidence levels can be used to interpret the score changes at a particular level of certainty for individuals with schizophrenia.
Long short-term prediction guides human metacognitive reinforcement learning
Authors: Lee Sang Wan , Kim Dongjae , Lee Jee Hang , Jung Wooseok , Kim So Hyun 
Published: June 2023

Abstract
Long-term prediction ensures stable but slow learning. Short-term prediction is fast but deemed to be risky in context-changing environments. To understand how humans resolve this conflict, we fitted nine biologically plausible reinforcement learning models to 82 human behavior data using a human-model policy matching method. One meta-RL model replicates subjects' context-dependent behavior, passing underfitting and overfitting tests. The same model survived a generalizability test simulating various Markov decision tasks and an adaptation test in which task structure, reward, and uncertainty change unexpectedly. Critically, the model’s ability is attributed to long- and short-term predictions about state transition and reward. Quantitative analyses revealed that conventional instant prediction error and its underlying long-term baseline are sufficient for context embeddings. These findings generate a long short-term prediction hypothesis: humans translate short-term into long-term predictions for context generalization while self-evaluating their long-term predictions to adjust short-term predictions. This creates a virtuous cycle of metacognitive generalization-adaptation.