bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arterial stiffness measured by pulse wave velocity correlated with cognitive decline in hypertensive individuals: A systematic review
Authors: Aimagambetova Botagoz , Ariko Taylor , Merritt Stacy , Rundek Tatjana 
Published: June 2023

Abstract

Background
Arterial stiffness is a degenerative modification of the arterial wall significantly influencing normal aging, longevity, and vascular health. Hypertension is a major risk factor for the development of arterial stiffness, which can lead to changes in cerebral perfusion and cognitive dysfunction. This, in turn, can increase the risk of cognitive decline. Pulse wave velocity (PWV) is an established gold standard for measuring arterial stiffness. Studies have shown that individuals with hypertension and elevated PWV are more likely to experience worse cognitive decline compared to those with either condition alone. The current literature, however, demonstrates controversial results. The aim of this article is to review the most recent published studies linking arterial stiffness to cognitive function in individuals with arterial hypertension.
Methods
We conducted a systematic review following the Cochrane protocol that was registered through the NIHR PROSPERO system. The PRISMA 2020 guidelines were used for reporting the systematic review. PubMed, Embase, Web of Science, CINAHL, and Cochrane databases were searched for relevant publications from early June to the end of December 2022. This review includes publications with a sample size of at least 500 participants older than 45 years. Screening of abstracts and full-text review of chosen articles were carried out through the Covidence.
Results
A total of 434 articles were selected for the full-text review. Twenty-four longitudinal studies and four cross-sectional designs that met the inclusion criteria were selected for the comparisons. The total sample size for these studies was 56,946 individuals. Twenty-seven studies (95%) demonstrated a significant association between arterial stiffness and cognitive dysfunction in hypertensive individuals. One study reported an association between stiffness and cognition independent of blood pressure (5% of the total population).
Conclusion
The results of this systematic review showed that arterial hypertension is one of the most important factors linking arterial stiffness to cognitive disorders. Pulse wave velocity was shown to be a strong measure associated with cognitive decline in aging individuals with chronically elevated blood pressure. Early screening for arterial stiffness, hypertension treatment, and effective prevention of cerebrovascular disease are imperative for cognitive health.
NIHR PROSPERO registry ID: CRD 42022379887
Investigation of Nursing Students' Opinions on HPV Infection and HPV Vaccine in Turkey: A Qualitative Study
Authors: ÇETİN Serpil ABALI , ÇINAR Derya 
Published: June 2023

Abstract
Background A number of interventions are needed to remove barriers to early screening for cervical cancer. A step-by-step strategy is required for these interventions to be successful. The first stage will be building consensus among trained health care providers, policy makers and educators. This study aimed to determine nursing students’ opinions about HPV infection and HPV vaccine.Methods A qualitative focus group discussion study. A state university in western Turkey Undergraduate nursing students recruited through purposive sampling. The research data were collected on an online platform with the focus group interview method by using the Participant Information Form and Semi-Structured Interview Form.Results Three main themes (HPV infection/vaccine perception, severity perception, suggestions and requests/facilitators) and eight sub-themes were developed based on the thematic analysis of the research findings.Conclusions According to the findings, it was concluded that nursing students’ opinions on HPV infection and HPV vaccine were affected by factors related to cultural, religious and sexual behaviors. Based on study results, it is suggested to organize national cervical screening programs to increase public’s knowledge and awareness on the subject in accordance with the socio-cultural norms of the society with the agreement and cooperation of educated health service providers, policy makers and educators.
Assessment of sugarcane bagasse through thermo-kinetic study as sustainable energy resources
Authors: Parmar Pankaj , Meiakp B. C. , Mukherjee Subhrajit 
Published: June 2023

Abstract
The improper and careless disposal of sugarcane bagasse (SCB) has drawn much attention. To use biomasses, looking at their potential as a bioenergy source is critical. Using biomass and biochar to generate bioenergy in this situation requires understanding the thermal conversion processes of these two materials. With the use of kinetic isoconversional methods and thermogravimetric analysis (TG), which incorporates thermodynamic parameters for non-isothermal studies using Ozawa-Flynn-Wall (OFW), Kissinger- Akahira-Sunose (KAS), and Friedman, Understanding the thermal behavior of SCB biomass residue and his biochar was the goal of this work. Thermal studies were carried out at 10, 20, 30, and 40°C min− 1 rates of heating in an inert and oxidizing atmosphere. The most significant loss rate for devolatilization occurred at 200°C, while the maximum mass loss rates for cellulose and lignin occurred at 350°C and 510°C, respectively.
Cross-species transferability of soybean SSR markers to yam bean (Pachyrhizus erosus L.): an underutilized crop for diversity analysis
Authors: Jena Biswajit , Pati Kalidas , Donde Ravindra , Acharya Varsha , Dash Goutam Kumar , Giri Alok Kumar , Chauhan Vijay Bahadur Singh , Nedunchezhiyan Maniyam 
Published: June 2023

Abstract
Yam bean (Pachyrhizus erosus L.) is an underutilized tuber crop that has recently gained popularity because of its enormous advantages in terms of nutrition and health. To date, there are no such potential molecular and genomic tools are available for the improvement of the yam bean crop that could help in studying genetic diversity or to identify and selecting elite cultivars for their conservation. The present study has used 67 SSR markers from soybean crops and checked their transferability in the 140 accessions of the yam bean, which identified 15 polymorphic novel SSR markers that showed cross-species transferability. These SSR markers show diversity dissimilarity percentage of 0.42 among the all accession and polymorphic information content (PIC) ranging from 0.03 to 0.84 with a mean of 0.36. Among the 140 accessions of yam bean, the SSR markers showed major allele frequency varying from 0.22 to 0.99 with an average of 0.68. The highest allele frequency, 0.99, was observed in SSR marker GMES0011. The population structure K-3 was identified based on the values of delta K and maximum likelihood (K) among the population of the yam bean. In the AMOVA analysis, identified genetic variance obtained among the population and within the population was 21% and 79%, respectively. These 15 soybean SSR markers successfully differentiated the yam bean accessions in to three groups. The present finding could be used to design a breeding strategy for the yam bean, to discover donor parent with untapped genetic potential for improvement and promote crop preservation.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning
Authors: Wang Shuhong , Xiong Binyuan , Tian Yin , Hu Quan , Jiang Xuheng , Zhang Ji , Chen Lin , Wang Ruilie , Li Mo , Zhou Xin , Zhang Tianxi , Ge Hongfei , Yu Anyong 
Published: June 2023

Abstract
Survivors experiencing acute carbon monoxide poisoning (ACMP) tend to develop white matter injury (WMI). The mechanism of ACMP-induced WMI remains unclear. Considering the role of ferroptosis in initiating oligodendrocyte damage to deteriorate WMI, exploring therapeutic options to attenuate ferroptosis is a feasible approach to managing WMI. Our results indicated that ACMP induced accumulation of iron and reactive oxygen species (ROS) eventually leading to WMI and motor impairment after ACMP. Further, ferrostatin-1 reduced iron and ROS deposition to alleviate ferroptosis, thereafter reducing WMI to promote the recovery of motor function. The nuclear factor erythroid-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway was found to be involved in alleviating ferroptosis as seen with the administration of ferrostatin-1. The present study rationalizes that targeting ferroptosis to alleviate WMI is a feasible therapeutic strategy for managing ACMP.
Finding best orthogonal channels through arbitrary optical
systems using integrated photonic processors
Authors: SeyedinNavadeh SeyedMohammad , Milanizadeh Maziyar , Zanetto Francesco , Ferrari Giorgio , Sampietro Marco , Sorel Marc , Miller David , Melloni Andrea , Morichetti Francesco 
Published: June 2023

Abstract
Modes of propagation are generally defined as the eigensolutions of the wave equation in a given system. When propagation occurs through complicated or highly scattering media, however, modes are better identified as the best orthogonal communication channels to send information between sets of input and output apertures. Here, we demonstrate that we can find optimum bi-directional orthogonal communication channels through arbitrary and scattering optical systems using photonic processors. The processors, made from meshes of tunable Mach-Zehnder interferometers in silicon photonics, configure themselves based on simple power maximization or minimization algorithms, without external calculations or calibration or any prior knowledge of the optical system. The resulting communication mode channels correspond to a singular-value decomposition, performed by the photonic processors, of the entire complex optics. Cross-talk below -30dB is observed between channels even in the presence of distorting masks or partial obstructions; in such cases, the beams bear little resemblance to conventional mode families, but show orthogonality nonetheless.
The thermal DLTS study of defect states of PELLE polymer
Authors: Rusnák Jaroslav , Pecz Michal , Škoviera Ján , Klbik Ivan 
Published: June 2023

Abstract
Thermal Deep Level Transient Spectroscopy (DLTS) technique was applied to study the defect states and their activation energies of polyurethane-based polymer network (PELLE) insulator. It was demonstrated that decomposition analysis of exponential transients allows a more accurate determination of the activation energy of the defective states. Two groups of activation energies for the PELLE polymer were observed, ranging from 0.49 eV to 1.9 eV and − 7.84 eV to -2.53 eV, which were assigned to changes of bond properties in the hard and soft segments of the studied polymer, respectively. The applicability of the DLTS method for the characterization of polymers was demonstrated. It was shown that the DLTS technique could contribute to a more comprehensive picture of the properties of polymers.
Indicators From the Quality of Soil Management Using Dimensional Analysis
Authors: Manoel Márcia Pereira Silva , Ferraz Camila Porfírio Albuquerque , Fengler Felipe Hashimoto , Albiero Daniel , Pereira Elisabeth Teixeira , Ribeiro Admilson Írio 
Published: June 2023

Abstract
For the agro-environmental management the use of indicator variables from soil management combined in the form of an index may represent an alternative for the characterization from the quality of management and its response to the level of the environmental fragilization from locals with agrosilvopastoris activities in watersheds. In this scope, the work associated, through the method of dimensional analysis some of the variable indicators from the soil’s quality management aiming applicability in the agro-environmental management of agrosilvopastoral activities, these are: the geometric mean diameter of the aggregates, mechanical resistance to penetration, permeability coefficient, natural covering, the local of the agrosilvopastoral management, organic matter, effective root depth, exposed soil and analogue anthropic pressure in the management area. The application of dimensional analysis on these variables enabled the elaboration of six dimensionless indexes, two with applicability in relational analysis of areas and four applicable in the analysis of embrittlement and quality of soil management.
Dissecting Lymph Node Stations Into Separate Specimens During Gastrectomy For Gastric Cancer Improves The Quality Of Nodal Status Evaluation: a retrospective cohort study
Authors: Fernström Aleksi , Kokkola Arto , Korpela Akseli , Puolakkainen Pauli , Louhimo Johanna 
Published: June 2023

Abstract
Background
In gastric cancer (GC), the pN-stage is an important prognostic factor influencing treatment. In this study, we explored whether dissecting lymph node stations into separate specimens affects the quality of nodal status evaluation and patient outcome.
Methods
The clinical data of 130 GC patients treated at the Helsinki University Hospital between 2016-2019 was reviewed. The processing of the surgical specimen before the pathological examination was assessed from the operation records and pathology reports.
The association of the number of examined lymph nodes with other variables was assessed and multivariate survival analysis was performed to explore the independent prognostic factors in disease specific survival.
Results
Dissecting lymph node stations into separate specimens before pathological evaluation yielded a significantly greater number of examined lymph nodes compared with a specimen without intervention (median 34.5 vs 21.0, p<0.001). The pT-stage, the pN-stage and the extent of lymphadenectomy were identified as independent prognostic factors, whereas dissecting the specimen’s lymph node stations did not associate with survival.
Conclusions
Dissecting lymph node stations into separate specimens results in a greater number of examined lymph nodes, which may lead to a more reliable pN-stage assessment.
Lifestyle factors, physical health, and life satisfaction among Chinese community-dwelling older adults: a longitudinal analysis
Authors: Peng Man-Man , Liang Zurong 
Published: June 2023

Abstract
Background
The study aims to investigate the long-term effects of lifestyle-related factors and physical health on subjective well-being among Chinese community-dwelling older adults with transitions in mental health conditions.
Methods
Using data from the China Health and Retirement Longitudinal Study (CHARLS), the analytic sample of this study included 1068 older adults who had participated in the surveys in both 2011 and 2018. Multivariate regression was used to examine the longitudinal associations of lifestyle-related factors and physical health with the subjective well-being of older adults. Additionally, distinct trajectories of their depressive symptoms were considered.
Results
Multimorbidity was found to be significantly related to baseline and follow-up depressive risk in older adults. Shorter sleep duration was associated with baseline depression risk. Compared to nondrinkers, current alcohol drinkers reported significantly more severe depressive symptoms. At baseline, current smokers were more likely to have a lower degree of life satisfaction than nonsmokers. Among older adults with chronic depression at the 7-year follow-up, former smokers tended to have lower life satisfaction than nonsmokers.
Conclusions
Our findings identified drinking alcohol and having a shorter sleep duration as modifiable lifestyle-related risk factors for late-life depression and smoking as a detrimental factor for life satisfaction in Chinese community-dwelling older adults. Multimorbidity was a significant predictor of more depressive symptoms at the 7-year follow-up. Our findings have implications for future psychosocial interventions that target the alleviation of depressive symptoms and the promotion of life satisfaction in older Chinese people based on their different long-term mental and physical health conditions.
Quantitative risk analysis of the sediment heavy metals using the positive matrix factorization-based ecological risk index method: Case of the Kuye River, China
Authors: Zhang Yaning , Wu Xijun , Dong Ying , Zhao Jian , Liu Jing 
Published: June 2023

Abstract

The risk sources of heavy metals (HMs) in river sediments are the key to pollution mitigation and risk control in coal mining area. Indeed, fifty-nine sediment samples were collected from the Kuye River and analyzed for eight HMs (Zn, Cr, Ni, Cu, Pb, As, Cd, and Hg). The ecological risks resulting from different sources were evaluated through an integrated method that combines the potential ecological risk index (RI) with positive matrix factorization (PMF) model. The obtained results showed that: the eight HMs contents in sediments exceeded the soil background values of Shaanxi Province. The average sediment Hg content was 3.42 times higher than the Hg background value. HMs in Kuye River sediments were mainly derived from industrial, traffic, agricultural pollution sources, and coal-mining sources according to the obtained PMF results. The RI indices ranged from 26.15 to 483.70. Hg contributed the most to ecological risk in the study area, showing a contribution rate of up to 75%. In addition, 28.8% of sampling sites belonged to the serious ecological risk. The coal-miningsource exhibited greatest impact on the river ecosystem (48.79%), followed, respectively, by traffic(34.41%), industrial (12.70%), and agricultural pollution (4.10%) sources according to the PMF-based RI model. These results indicated that the largest contributors to the environmental ecological risks are not necessarily the major sources of environmental pollutants for the river sediments. These findings highlight the ecological risks linked to potential sources of sediment HMs contamination and provided valuable information on the reduction of corresponding risks for local environmental managers.
Evaluation of Independent Parameter Effects on Sesame (Sesamum indicum L.) Yield and Water Productivity in Tape Drip Irrigation
Authors: Salamati nader , Danaie Amirkhosro , Behbahani Leila , azadi abolfazl 
Published: June 2023

Abstract
As water scarcity becomes more acute in many parts of the world, increasing the effectiveness with which agricultural water resources are used is a priority for enhanced food security of water. Experiment was carried in the fromed out of randomized complete block design (RCBD) with three replications in Behbahan Agricultural Research Station in Khuzestan province southwest Iran, during the 2018 and 2019 growing seasons. To evaluate of Yield and Water Productivity of Sesame using Drip Tape Irrigation system, different water levels based on water requirements (40, 60, 80, and 100% of the water requirement) and three sesame varieties (Darab1, Dashtestan2, and Shevin) were considered as main plots and sub plots, respectively. According to obtained results, Comparison of the average interaction effects of irrigation and various varieties showed that the Darab1 variety, which had the best results with 100% water requirement treatment and had 73.3 seeds per capsule, 125.7 capsules per plant, 2.703 gr of 1000-seed weight, and 1314.5 kg.ha− 1 yields, was superior and came in first place. The analysis of the regression model's, beta coefficient and the Pearson correlation coefficient for the studied traits revealed a trend toward increasing beta coefficient and Pearson correlation coefficient values as water consumption increased from treatment 40–100% water requirement. The increasing trend in beta and Pearson correlation coefficients had a higher slope from 40 to 80% of water requirement levels and a lower slope from 80 to 100% of water requirement levels. At the level of 80% of water requirement, yield and water productivity had the highest beta coefficients (0.622 and 0.633) and Pearson correlation (0.712 ** and 0.730 **) with capsules per plant, respectively. Less fluctuation of beta and Pearson correlation coefficients from the level of 80 to 100% of water requirement compared to other irrigation levels caused the level of 80% of water requirement to be introduced as the optimal level of irrigation, and in conclusion, the highest water productivity was observed in Darab1 variety. Additionally, this research highlights the possibility of using Darab1 variety in study area and region with similar conditions.
Associations between fasting plasma glucose trajectories and cardiovascular disease among older Chinese adults
Authors: chen quan , Du Jinling , Hong Xin 
Published: June 2023

Abstract
Background
The aim of this study was to investigate the relationship between fasting plasma glucose (FPG) trajectories and the risk of cardiovascular disease (CVD) in the elderly population aged 65 years and above in China based on a community-based cohort study.
Methods
We included 7,079 participants aged 65 and above from a cohort based on the health examination data in Nanjing after following strict inclusion and exclusion criteria. FPG and other covariates were repeatedly measured from 2018 to 2020. The trajectory analysis model (GBTM) was used to construct the trajectories of fasting blood glucose index (FPG logarithm, so that it obeys the normal distribution). And the first cardiovascular disease in 2021 was used as the outcome event. A Cox proportional hazards model was used to examine the association between FPG trajectories and incident cardiovascular disease.
Results
We identified three FPG trajectories based on 2018 FPG measurement and change patterns during 2018-2020: low level (n=5,635), medium level (n=1,201), and high level (n=243). In 2021, we documented 70 incident cardiovascular disease events. Compared with the low-level group, groups with higher level FPG trajectories had a higher risk of CVD events. Adjusted HRs (95% CIs) were 1.63(0.94-2.85) for the medium-level group, and 2.79(1.19-6.52) for the high-level group. After further adjusting for metabolic indicators, we observed similar results. Among the 70 outcome events, there were 64 cases of stroke outcome events. And in the outcome event of stroke, we also found similar results, independent of age, sex and other covariates.
Conclusions
Higher levels of fasting plasma glucose trajectories were associated with a higher risk of cardiovascular disease or stroke outcomes in the elderly population in China.