bluuebunny/crossref_metadata_2025_split huggingface dataset:
BRIDGING SILOS: EVALUATION OF AN INNOVATIVE REGIONAL SENIOR TRANSPORTATION SERVICE
Authors: Jansen Taylor , Silverstein Nina , Dugan Beth , Lee Chae Man , Xu Shu , Su YanJhu 
Published: December 2022

Abstract
A pilot study was conducted for a regional transit authority (RTA) to evaluate the implementation of a customized software to increase ridership, trips, destinations and coordination of rides among four Councils on Aging (COA) using RTA vans to serve rural communities in north central Massachusetts. Baseline and follow up ride data were collected from each COA from Fall 2019 (N= 178 riders; N= 4,230 trips) and Fall 2021 (N= 131 riders; N= 2,020 trips) and from 59 stakeholder interviews with riders, drivers, dispatchers, and staff from the COAs, RTA, and software company. The evaluation found after 6 months that while the goals of the pilot were not yet achieved, due in part to external factors such as the COVID-19 pandemic and driver shortage, valuable lessons were learned including the importance of balancing provider goals of efficiency and reporting with rider needs of driver hands-on assistance and friendly scheduling support.
GERONTOLOGIC BIOSTATISTICS: MERGING WITH DATA SCIENCE AND TOWARD PERSONALIZED MEDICINE
Authors: Shardell Michelle , Murphy Terrence , Allore Heather 
Published: December 2022

Abstract
The sub-discipline of gerontologic biostatistics (GBS) was introduced in 2010 to emphasize the special challenges encountered in the design and analysis of research studies of older persons. These challenges center on the multifactorial nature of human aging, characterized by the parallel and progressive deterioration of diverse organ and cellular systems that eventually results in death. Ten years after the introduction of GBS, which initially focused on important aspects of design and analysis that ensure their statistical validity, we update how GBS has been enriched by evolving practices. We present individual sessions on three seminal developments in the practice of GBS: integration of data science and multiple streams of data, including those automated and or multidisciplinary in nature; enhanced methods of addressing the heterogeneity of treatment effects from health-related interventions for older patients; and how interactive visualization can help specific patients locate themselves along the continuum of individualized treatment effects. We conclude our presentation with a session that reviews three prominent trends in the validation of the heterogeneity inherent to the assessment of health among older adults. Reflecting this era of big gerontological data, we discuss several established modeling approaches for validation, the proliferation of signal intensive behavior phenotypes, and the deep characterization of phenotypes through OMICS studies and multimodal approaches. All talks discuss pitfalls and areas of future development and draw from published studies. We are submitting as an interest group collaborative panel submission between two interest groups: Epidemiology of Aging and Measurement, Statistics and Design.
PREDICTORS OF DEPRESSION AMONG MIDDLE-AGED AND OLDER MEN AND WOMEN IN EUROPE: A MACHINE LEARNING APPROACH
Authors: Aichele Stephen , Handing Elizabeth , Strobl Carolin , Jiao Yuqin , Feliciano Leilani 
Published: December 2022

Abstract
The high prevalence of depression in a growing aging population represents a critical public health issue. It is unclear how social, health, cognitive, and functional variables rank as risk/protective factors for depression among older adults and whether there are conspicuous differences among men and women. We utilized random forest analysis (RFA), a machine learning method, to compare 56 risk/protective factors for depression in a large representative sample of European older adults (N = 67,603; ages 45-105y; 56.1% women; 18 countries represented) from the Survey of Health, Ageing and Retirement in Europe (SHARE Wave 6). Self-rated social isolation and self-rated poor health were the most salient risk factors, jointly accounting for 22.0% (in men) and 22.3% (in women) of variability in depression. Difficulties in mobility (in both sexes), difficulties in instrumental activities of daily living (in men), and higher self-rated family burden (in women) accounted for an additional but small percentage of variance in depression risk (2.2% in men, 1.5% in women). To our knowledge, this is the first large, multi-country study to use machine learning to compare a broad range of social, health, functional, and cognitive variables as concurrent risk/protective factors for depression in middle-aged and older adults—and with analyses conducted independently for women and men. The results point to the importance of screening for depression risk within this age demographic during routine medical visits (i.e., when assessing general health status) and further indicate that such screening may be improved by inclusion of measures of perceived social isolation.
INNOVATIONS IN AGING: CREATING A TRANSDISCIPLINARY RESEARCH COLLABORATIVE GRADUATE FELLOWSHIP PROGRAM
Authors: Martin Diane , Latimer Nia , Bowers Katherine 
Published: December 2022

Abstract
Social isolation impacts nearly one-quarter of community dwelling adults aged 65+ in the United States. It is associated with poor physical and mental health, cognitive decline, higher healthcare costs, and early mortality. Older adults are at greater risk because they are more likely to live alone, experience a shrinking social network from loss of family and friends, and encounter limitations with driving and mobility resulting from chronic health conditions and sensory impairments. Social isolation in later life is not new; however, the COVID-19 pandemic brought to light the increased risk for negative outcomes. Reducing social isolation is a priority area for our state’s Department of Aging (DoA), and the updated State Plan on Aging highlights the need for innovative approaches to develop and strengthen initiatives addressing social isolation among older adults. The DoA is advancing multiple projects, including a partnership with our public university to create a transdisciplinary graduate fellowship program. The program brought together professional students from medicine, nursing, pharmacy, and social work and resulted in a community of practice in which fellows engaged with DoA and university faculty to share best practices and receive training in transdisciplinary research. In this session, the first presentation will focus on development of the fellowship program and highlight the success of the inaugural year; the second session will focus on the future goals of the fellowship program, and the third presentation will share how we plan to expand the partnership between our public university and our state’s Department of Aging.
YEAR ONE AND BEYOND: SUSTAINING A COLLABORATIVE AGING FELLOWSHIP PROGRAM
Authors: Martin Diane 
Published: December 2022

Abstract
A graduate aging fellowship experience can provide participants with unique opportunities for professional development in interdisciplinary and transdisciplinary research, community engagement, and team science. Program success is contingent on multiple factors beyond participant recruitment and customizable curriculum to meet the educational goals of individual participants. Stakeholder buy-in, strategic planning, and identification of funding streams are all necessary to support an internal program beyond its first year. In this session, we will offer guidance in planning, building, and sustaining a fellowship program for current graduate students with a professional interest in supporting older adults.
"WHAT'S YOURS IS MINE": A DYADIC STUDY OF EVERYDAY EMOTIONAL EXPERIENCES AND CORTISOL IN OLDER COUPLES
Authors: Pauly Theresa , Kolodziejczak Karolina , Drewelies Johanna , Ashe Maureen , Madden Kenneth , Ram Nilam , Gerstorf Denis , Hoppmann Christiane 
Published: December 2022

Abstract
Older partners’ health is linked; individuals’ physiological arousal can be shaped by their own and their partner’s emotional experiences. This study examines those associations using repeated daily life assessments (7 days) of physiological arousal (cortisol), positive affect (PA), and negative affect (NA) obtained from 321 older couples. Results from multi-level models revealed, at the between-person level, that individuals with higher average cortisol had partners with higher overall NA; and, at the within-person (momentary) level, that cortisol was lower in moments when the partner’s PA was higher than usual and when one’s own PA was higher and NA was lower than usual. On a day level, cortisol output was lower on days with lower own NA and with higher partner PA, particularly when relationship satisfaction was high, but unrelated to own PA. The findings emphasize the importance of considering how members of a dyad influence each other’s health in old age.
UNDERSTANDING THE PALLIATIVE CARE INFORMATION CIRCULATING ON TWITTER DURING THE CORONAVIRUS PANDEMIC
Authors: Inoue Megumi , Hashemi Mahdi , Li Meng-Hao , Kulkarni Rajendra , Koizumi Naoru 
Published: December 2022

Abstract
Palliative care is a growing medical specialty. While its value has become particularly evident during the pandemic, it faces various challenges including misconceptions among the general public, a lack of awareness of its benefits, and limited/sporadic access and coverage by Medicare. Given the increasing number of people sharing their health information and seeking healthcare information on social media where misinformation is widely spread, this study examined types of information on palliative care circulated on Twitter. A total of 26,495 English Tweets were collected 01/01/2020 – 12/30/2021 using the keywords “Palliative” and “Covid” or “Corona”. We manually developed a framework for coding/classifying the first 6,000 Tweets. Of those, 5,308 were unrelated Tweets (e.g., advertising palliative care seminars/conferences). Among the remaining Tweets, persistent myths were observed (e.g., palliative care is only for dying people) and were labeled accordingly. In addition, while some people mentioned negative impact of the pandemic on palliative care (e.g., shortage of beds), others found value in palliative care and reported positive changes due to the pandemic (e.g., telehealth in palliative care). Consequently, the following categories were defined for Tweets: i) Recognized benefits (203 Tweets); ii) Positive impact of the pandemic on palliative care (120 Tweets); iii) Negative impact of the pandemic on palliative care (333 Tweets); iv) Myth (63 Tweets). We will use these manually classified Tweets to train machine-learning algorithms to automatically classify the remaining tweets, aiming to obtain a comprehensive understanding of palliative care information circulating on Twitter and seek ways to promote palliative care use.
THE CORONAVIRUS JOB RETENTION SCHEME AND MENTAL HEALTH AMONG OLDER WORKERS: EVIDENCE FROM ENGLAND
Authors: Gessa Giorgio Di , Zaninotto Paola 
Published: December 2022

Abstract
The COVID-19 pandemic has led to major economic disruptions. In March 2020, the UK implemented the Coronavirus Job Retention Scheme –known as furlough –to minimize the impact of job losses. So far, little is known on the mental health impact of this scheme on older workers, and on whether this varies by job characteristics. Exploiting longitudinal data from Wave 9 (2018/19) and two COVID-19 sub-studies (June/July 2020; November/December 2020) of the English Longitudinal Study of Ageing we use logistic and linear regression models to investigate associations between changes of employment and mental health during the pandemic. About 10% of respondents aged 52-67 were furloughed in the initial phase of the pandemic. Overall, employment disruption was associated with changes in mental health, although results suggest differences by pre-pandemic job characteristics (i.e. hours worked, physical effort, social class, and stress measured by the effort-reward imbalance model).
CHILDHOOD AND MIDLIFE CULTURAL ENGAGEMENT AMONG KOREAN MARRIED COUPLES
Authors: Kim Kyungmin , Burr Jeffrey , Han Gyounghae , Kim Bon 
Published: December 2022

Abstract
Cultural reproduction theory posits that cultural resources transmit to the next generation, suggesting a lingering effect of parental influences on cultural experiences in adulthood. Further, middle-aged adults’ cultural engagement may not only be influenced by their own childhood experiences but also their spouses’ experiences. This study extends our understanding of childhood and midlife cultural engagement of married couples, using a sample of 1,271 couples (age 49–66) from the 2012 Korean Baby Boomer Panel Study and Korean Forgotten Generation Study. Results from Actor Partner Interdependence Models showed that beyond one’s own childhood cultural engagement, spouse’s childhood cultural engagement was associated with levels of perceived cultural engagement at midlife (for both husbands and wives) and number of arts and cultural activities at midlife (only for husbands). Given the cross-spousal associations in cultural engagement among Korean middle-aged couples, both spouses’ cultural resources need to be considered for policy implications.
SOCIAL DETERMINANTS OF HEALTH AND WILLINGNESS FOR END-OF-LIFE DISCUSSION AMONG KOREAN AMERICAN IMMIGRANTS
Authors: Noh Hyunjin , Choi Eunyoung , Lee Lewis , Lee Hee 
Published: December 2022

Abstract
This study aimed to examine social determinants of health (SDH) associated with Korean American (KA) immigrants’ willingness for end-of-life discussions with family and doctors. A self-administered, cross-sectional survey was conducted with 259 KAs in Alabama. Demographic, health, acculturation, and SDH information were collected. Binary logistic regression analyses were conducted to examine associations between SDH and willingness for end-of-life discussion. Most participants were willing to discuss with family (94%) and doctors (82%). Those aware of hospice care were more likely to have willingness for discussion with family and doctors. Those who could not see a doctor because of cost and who had higher threats to interpersonal safety were less likely to have willingness for discussion with family. Those with more chronic conditions and higher social isolation were less likely to have willingness for discussion with doctors. Interventions aimed to promote KAs' end-of-life discussions should consider the SDH identified in this study.
CHALLENGES RELATED TO DATA SOURCES FOR RWE IN AGING RESEARCH
Authors: Lu Kevin 
Published: December 2022

Abstract
Numerous challenges remain in research to generate RWE for FDA approvals and other health care decision-makers or stakeholders. This is particularly true for research to evaluate the effectiveness of pharmaceutical care and patient outcomes in older populations. For example, data sources available for RWE in the older populations are limited and data access can be daunting; identifying appropriate data sources for FDAapprovals remain challenging. Most of the FDA approvals are based on RWE rely on multiple data sources instead of a single database. In addition, pharmacoepidemiologic studies in older adults using RWD are often limited in capturing important clinical information and prognostic factors that are useful for decision-makers. Polypharmacy, frailty, and patient outcomes measures are often inconsistent depending on specific databases and thus produce controversial results. We will discuss different data sources appropriate for pharmacoepidemiology research and make comparisons and contrasts of different research approaches using different databases.
USE RWE TO IMPROVE DRUG INFORMATION FOR GERIATRIC PATIENTS
Authors: Li Minghui , Watts Chelsea 
Published: December 2022

Abstract
Older adults are the main users of medications. However, they are usually excluded from clinical trials due to comorbidity and polypharmacy. Older adults, especially those 75 years and older, are underrepresented in clinical trials. This creates a unique opportunity to use RWE to improve the quantity and quality of drug information for geriatric patients. The quality of RWD is critical to have information on patient population, comparator, measurement, and endpoints. Data linkage is encouraged if key variables are not included in one data source. In addition, external controls based on RWE can be used when clinical trials are unethical or impractical. They can be applied for older adults, rare diseases, and under-represented minorities. For conditions common in older adults (e.g. Alzheimer's disease, lung cancer, and osteoporosis), RWE is greatly needed for all geriatric age groups. The entire spectrum of geriatric populations could identify age differences in efficacy and safety outcomes.
CARE NETWORKS OF RURAL APPALACHIAN FAMILY CAREGIVERS AND PERSONS LIVING WITH DEMENTIA
Authors: Savla Jyoti , Roberto Karen , Blieszner Rosemary 
Published: December 2022

Abstract
Dementia care research typically focuses on primary family caregivers with limited consideration of their engagement with a broader care network and the geographic area in which they reside. Using a mixed-methods approach, we analyzed care networks of 163 primary caregivers and their relative living with dementia in rural Virginia. Six distinct care network types emerged based on the primary caregiver's gender, relationship to the person living with dementia, and presence of other informal caregivers. Networks differed by the caregiver’s emotional connectivity with family/friends and feelings of caregiver strain, role overload, and loneliness. Caregivers’ service use attitudes and support service utilization varied across network types and across divergent economic resources of the rural counties in which families resided. Findings establish a framework for understanding the types and influences of care networks and tailoring services to support dementia family caregivers in diverse rural areas.
CHANGES IN RURAL AND URBAN FAMILY CAREGIVING NETWORKS IN THE MIDWEST DURING THE COVID-19 PANDEMIC
Authors: Ashida Sato , Cho Hyunkeun , Thompson Lena , Williams Kristine , Koehly Laura , Schneider Haley , Donohoe Maria , Hossain Lubna 
Published: December 2022

Abstract
This study elucidates the changes in family caregiving networks during the COVID-19 pandemic and its implications on caregiver well-being. Eighty-two caregivers of individuals diagnosed with dementia within the past 2 years participated in this study to test a post-diagnosis intervention that provides a community care planning service that connects caregivers directly to community-based services. Caregivers completed telephone surveys at baseline and 3- and 6-month follow-up. The number of network members engaging in malfeasant (negative) social interactions increased by 0.798 every 3 months (p=0.002). Members engaging in uplifting interactions decreased, especially among intervention participants, by 1.93 every 3 months (p=0.047); urban caregivers reported greater decrease than rural (p=0.006). Participants in intervention group showed a trend for greater decrease in COVID-19 related distress (10-point scale) over time compared to control group (p=0.059); those with more members engaging in uplifting interactions reported lower distress (p=0.017) regardless of intervention status, network size, and rurality.
CONTEXT MATTERS IN DECISION-MAKING: CAREGIVING NETWORKS OF AFRICAN AMERICAN DEMENTIA DYADS
Authors: Johnson Kalisha Bonds , Epps Fayron , Song MinKyoung , Lyons Karen , Hepburn Kenneth , Driessnack Martha 
Published: December 2022

Abstract
Limited research explores the contextual and cultural nuances within African American dementia dyads within the United States and how these factors influence decision-making processes. Through a secondary data analysis of semi-structured interviews, we examined decision-making processes in five African American dementia dyads related to how they navigated decisions for the person living with Alzheimer’s disease and related dementias (ADRD) across five unique contexts (e.g., mother with multiple daughters, mother with son and daughter where the son was the “primary” caregiver). Analysis revealed that within dyads, persons living with ADRD were involved in the decision-making processes, but the level of the involvement in decision making by the caregiving networks varied across dyads. Understanding the context in which decisions are made (i.e., within the dyad, across multiple family members in a caregiving network) has important implications in clinical practice and research. Interventions should be tailored to reflect these contextual and cultural nuances.
SENESCENCE-DERIVED PROTEIN BIOMARKERS DURING AGING AND OSTEOARTHRITIS
Authors: Schilling Birgit , Patel Sandip , Rose Jacob , Campisi Judith , Bons Joanna , King Christina , Schurman Charles 
Published: December 2022

Abstract
Aging is a complex biological process associated with progressive loss of physiological function and susceptibility to several diseases, such as cancer and neurodegeneration. As senescence burden increases with aging and becomes a risk factor for many age-related diseases we are specifically interested in senescence-derived aging signatures. We use cutting-edge proteomic workflows to investigate both the senescence-associated secretory phenotype (SASP) in tissue cultures. We are subsequently examining exosome proteins as well as lipid cargo in plasma from human young (20–26 yrs) and old cohorts and old (60–66 yrs) individuals. We will also present current work assessing senescence markers in cartilage and bone targeting underlying mechanisms and options for intervention for osteoarthritis. Overall, our focus is specifically directed towards senescence-derived biomarkers of aging.
AN AGE-RELATED POSITIVITY EFFECT IN HUMOR: AN ASIAN CONTEXT
Authors: Ng Zoe Ziyi , Yow W Quin 
Published: December 2022

Abstract
Humor plays a pivotal role in our interaction with people. According to the age-related positivity effect, older adults (OA) demonstrate more positive emotions and are better able to modulate negative emotions than younger adults (YA), suggesting an increase in humor appreciation with age. However, given the heterogeneity and complexity of humor, it is unknown if this effect holds across various types of humor in a culture with ambivalent attitudes toward humor (Yue, 2016). We explored age-related effects in the perception of four types of humor with Asian adults: incongruity-resolution/benign humor, aggressive humor, local-slang humor, and self-vs.-other-deprecating humor. Fifty-six Singaporean-Chinese OA (n=26;M=64.33) and YA (n=30;M=22.48) watched four short videos depicting the four types of humor in a randomized order. Participants rated how funny each video was (from a scale of 1-not funny-at-all to 5-very-funny), ranked them in the order of most-to-least-entertaining and answered questions on Future-Time-Perspective-scale and self-rated humor.Repeated-measures ANOVA found significant main effects of age, F(1,59)=6.60, p=.013, where OA gave higher ratings than YA (M=3.00 vs. 2.47), and humor-type, F(3,177)=26.87, p&lt;.001. There was a significant linear contrast in humor-type where aggressive and benign humor had the lowest ratings while self-vs.-others-deprecating humor had the highest ratings. Ranking analyses revealed that OA preferred local-slang and others-deprecating humor while YA preferred other-deprecating humor significantly above chance. Interestingly, there was no relationship between self-rated humor and future time perspective with age. Overall, OA displayed a greater appreciation of humor than YA, supporting an age-related positivity effect in an Asian context, despite preference differences. We would like to thank Prof Suzanne Flynn, Department of Linguistics and Philosophy, MIT, for her guidance, and the MOE Tier 2 Academic Research Fund Tier 2 (T2MOE2005) and SUTD Growth Plan Grant for Healthcare (SGPHCRS1902) awarded to the last author.