bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of second warm ischemia elimination on kidney graft function: an experiment and clinical study
Authors: Shabunin A. V. , Drozdov P. A. , Makeev D. A. , Nesterenko I. V. , Zhuravel O. S. , Astapovich S. A. , Lidjieva E. A. 
Published: July 2023

Objective: to evaluate the effectiveness of a new device for second warm ischemia (SWI) elimination in kidney transplantation (KT).Materials and methods. The study included clinical and experimental stages. The clinical stage included 63 patients out of 219 who underwent KT at Botkin Moscow City Clinical Hospital between July 2018 and August 2022. The inclusion criteria were kidneys from donation after brain death (DBD) donors with expanded criteria or kidneys from donation after circulatory death (DCD) donors, and an SWI time greater than 45 minutes. The first group consisted of 24 recipients operated on using the new SWI elimination device. The second retrospective control group consisted of 39 patients where sterile ice bags were used at the implantation stage. The groups had no statistically significant differences in the main recipient and donor characteristics, as well as in perioperative parameters. Also, from November 2021 to April 2022, 23 kidney autotransplantation experiments in female Landrace pigs were performed. The animals were cared for in accordance with the European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (Strasbourg, 18 March 1986). Efficiency of different SWI elimination techniques was compared on two experimental models: standard donor (group 1, n = 12) and asystolic donor (group 2, n = 11).Results. In the clinical trial group, mean graft temperature (tm) before reperfusion was statistically significantly lower in group 1 using the special SWI elimination device: 6.4 ± 1.7 °C (95% CI 3.2–8.5) versus 22.1 ± 2.3 °C (18.1–24.6), р < 0.001. The risk of delayed graft function (DGF) was 3.86 times higher (95% CI 1.11–13.43) with the standard SWI elimination technique. In the experimental group, in the subgroups using the new device (n = 12), graft tm before reperfusion was 5.1 ± 0.4 °C (95% CI 4.5–5.8), whereas in the ice bag subgroups (n = 11), tm was 29.3 ± 1.3 °C (95% CI 27.7–30.8), which was significantly higher (p < 0.001). The overall 1-week survival of the experimental animals was significantly higher in the SWI elimination device subgroup (logrank p = 0.036).Conclusion. The developed device is effective in eliminating SWI of renal graft.
Explosion, earthquake, and ambient noise recordings in a Pliocene sediment-filled valley: Inferences on seismic response properties by reference- and non-reference-site techniques
Authors: Malagnini L. , Tricarico P. , Rovelli A. , Herrmann R. B. , Opice S. , Biella G. , de Franco R. 
Published: July 2023

Abstract
Explosion, earthquake, and ambient noise recordings were collected at the eastern edge of a Pliocene sediment-filled valley, nearby the town of San Casciano dei Bagni (Tuscany, Central Italy). The anomalous amplification of amplitudes (as high as a factor of 20 between sediment and hard-rock sites) shown by classical spectral ratios were compared with results obtained by using non-reference-site techniques, like that of Nakamura (1989) and its receiver-function-like extension.
The explosion data were collected in June 1990, as part of a crustal refraction experiment carried out in the Monti Vulsini volcanic area. A linear array of 13 digital stations was deployed orthogonally to the eastern border of the Radicofani graben: 2 stations were set up on a bedrock outcrop, whereas the remaining 11 were deployed on soft sediments, 100 m apart, along a straight line toward the center of the valley.
During a second part of the study, two stations were left in the field to record local and regional seismicity, acquiring data from more than 150 events from a seismic swarm that occurred in the Monti Vulsini volcanic area in February 1992 with a maximum magnitude MD = 3.8. Spectral ratios were computed on the 41 strongest events, showing a seismic response consistent with that computed using explosion data, at least in the 0.5- to 4-Hz frequency band. Non-reference-site techniques were employed to analyze earthquake and noise data: although it is clear that the horizontal/vertical (H/V) spectral ratios describe some intrinsic properties of sites (noise and earthquake data give equivalent results), in our case, they failed in recognizing both resonances and amplification levels.
Large amplifications shown by classical spectral ratios were probably due to basin-induced surface waves and 3D resonances. Seismic waves recorded by a small (50m radius) 2D array deployed within the valley provided instrumental evidence for the existence of waves diffracted locally on lateral heterogeneities.
Leveraging Policy Changes Made in Response to COVID-19 to Advance Telehealth and Novel Treatment Approaches for People Who Use Opioids: Qualitative Perspectives From Two Rural North Carolina Counties
Authors: Chen Hillary , Knettel Brandon A. , Macon Harrison Lisa , Des Marais Andrea , Nelli Amanda , Campbell Hilary A. , Muhirwa Amnazo , McKellar Mehri S. , Gulur Padma , Guthrie Shauna 
Published: July 2023

Background The COVID-19 pandemic has been a catalyst for telehealth services for people who use opioids; however, the data show dramatic increases in opioid overdose deaths and ongoing lack of treatment options in North Carolina, particularly among rural residents. Methods We conducted a listening session and qualitative interviews with 10 health care professionals, administrators, and community partners providing services for individuals who use opioids in Granville and Vance counties. Data were analyzed with an applied thematic approach. Results Participants described several benefits of rapid expansion of telehealth services during the pandemic. Continued improvements in access to high-speed internet will be critical to maintain progress in rural areas. Participants advocated for integrated, co-located ser­vices and improved referral processes to minimize cost and burden of attending multiple appointments across sites. Integrated services could include medication for opioid use disorder (MOUD), mental/behavioral health support, primary medical care, and harm reduction services. Participants supported novel community-based strategies, such as mobile clinics, and described a need for after-hours and crisis services for opioid recovery in the region. Limitations The study was exploratory in nature and elicited the perspectives of providers serving two rural counties in North Carolina, which may not be generalizable to broader populations. We did not include the perspectives of people who use opioids in this study but will do so in upcoming research. Conclusions Participants were strong proponents of the benefits of telehealth and identified strategies for continuing recent progress in rural access to opioid treatment through novel integrated and community-based approaches.
Perceptions of North Carolina’s Medicaid Transformation: A Qualitative Study
Authors: Zimmer Rachel P. , Hanchate Amresh D. , Palakshappa Deepak , Aguilar Aylin , Wiseman Kimberly , Crotts Charlotte I. , Abdelfattah Lindsay , McNeill Sheena , Sostaita Daniel , Montez Kimberly 
Published: July 2023

Background In 2021, North Carolina switched 1.6 million beneficiaries from a fee-for-service Medicaid model to a managed care system. The state prepared beneficiaries with logistical planning and a communications plan. However, the rollout occurred during the COVID-19 pandemic, creating significant challenges. Little is known about how Medicaid Transformation impacted the experience of Medicaid en­rollees. Methods We conducted four focus groups (N = 22) with Medicaid beneficiaries from January to March 2022 to gain insight into their experience with Medicaid Transformation. A convenience sample was recruited. Focus groups were recorded, transcribed verbatim, and verified. A codebook was developed using inductive and deductive codes. Two study team members independently coded the transcripts; discrepancies were resolved among the research team. Themes were derived by their prevalence and salience within the data. Results We identified four major themes: 1) Participants expressed confusion about the signup process; 2) Participants had a limited understanding of their new plans; 3) Participants expressed difficulty accessing services through their plans; and 4) Participants primarily noted negative changes to their care. These findings suggest that Medicaid enrollees felt unsupported during the enrollment process and had difficulty accessing assistance to gain a better understanding of their plans and new services. Limitations Participants were recruited from a single institution in the Southeastern United States; results may not be transferable to other institutions. Participants were likely not representative of all Medicaid Transformation beneficiaries; only English-speaking participants were included. Conclusion As the transition process continues, the North Carolina Medicaid program can benefit from integrating recommendations identified by member input to guide strategies for addressing whole-person care.
Characteristics of Patients with Asthma Attack Followed in the Intensive Care Unit
Authors: KARAOĞLANOĞLU Selen , BOSTAN Özge , ÖCAL Serpil , ERSOY ORTAÇ Ebru , DEMİR Ahmet , KARAKAYA Gül , KALYONCU Ali Fuat 
Published: July 2023

Objective: Asthma attack is a critical reason for morbidity and mortality if not treated effectively at the right time. Data about the efficiency of noninvasive and invasive mechanical ventilation (NIV, IMV) in respiratory failure due to asthma attacks are scant. The aim of this study was to investigate the relationship between asthma-related factors, medical and NIV/IMV treatments received in the Intensive Care Unit (ICU), and the mortality rates and length of hospital stay, in asthma attacks.
Methods: The characteristics of patients with severe asthma treated in Hacettepe University Medical ICU for a ten-year period were analyzed from patient records retrospectively. The association between age, sex, comorbidities, asthma duration, treatment, adherence to the treatment, the effectiveness of NIV/IMV treatment if performed, and asthma attack severity, length of hospital stay, and mortality were investigated.
Results: A total of 22 patients were included in this study. In addition to medical treatment, eight (36.6%) patients received NIV, five (22.7%) received invasive mechanical ventilation (IMV), and five (22.7%) patients had both. Four (18.1%) patients died in the ICU. There was no significant relationship between these parameters and length of hospital stay and mortality. The relationship between baseline PaCO2, pH, and HCO3 and the difference of PaCO2, pH, and HCO3¯ changes were significant, indicating the correct and effective use of NIV/IMV.
Conclusion: NIV applications, which have been proven to be effective in hypercapnic respiratory failure, were also found to be effective in hypoxemic respiratory failure due to asthma attacks. The absence of a relationship between the investigated parameters and mortality revealed that the reasons for the mortality might be infections or comorbidities, not the respiratory tract.
Pouvoir attractif de l’association M-Crésol 1-Octen-3-Ol dans un type de diffuseur pratique pour <em>Glossina tachinoides</em> au Burkina Faso
Authors: Filledier J. , Mérot P. 
Published: July 2023

Après des études préliminaires menées sur l’attractivité de composés phénoliques dérivés des urines pour Glossina tachinoides Westwood, 1850, les recherches ont porté sur l’association de ces dérivés avec d’autres produits ; un mélange efficace est testé dans un diffuseur de longue durée permettant un emploi pratique dans le cadre d’une campagne de lutte. L’association M-Crésol l-Octen-3-01 dans un rapport de 3 pour 1, diffusée au moyen d’un tube de polyéthylène souple de 4 ml de contenance, semble répondre à cet objectif et être en mesure d’améliorer les techniques de piégeage pour une glossine du sous-genre Nemorhina. Pendant au moins 10 semaines, les captures de Glossina tachinoides sont multipliées par 2,5 avec l’emploi du piège biconique Challier-Laveissière. Le coût de ce diffuseur est de 230 francs CFA en juin 1988. Les différences avec les résultats obtenus par d’autres équipes de recherche sont discutées. L’impossibilité d’employer comme attractif, au Burkina Faso, l’urine elle-même est soulignée.
Instilling Islamic Values on STEAM Learning in Early Childhood Education to Produce Islamic Scientist
Authors: Rahmatullah Rahmatullah , Faeruz Ratna , Romadhon Dzikri Rahmat , Rahiem Maila D. H. 
Published: July 2023

<p><em>In Indonesia, most early childhood education institutions are affiliated with Muslim groups to educate future intellectuals who are clerics or knowledgeable about religion and scientists who advance science. This study aims to determine how teachers of Islamic Kindergarten/Raudhatul Athfal integrate Islamic values into STEAM instruction. The qualitative phenomenological method was employed in the research. The study enrolled 44 teachers and principals from eight Islamic Kindergartens/Raudhatul Athfal in five cities/districts throughout three provinces. The research revealed that instructors of Islamic Kindergarten/Raudhatul Athfal instill Islamic values into the STEAM curriculum by 1) integrating Islamic thematic; 2) conducting Tarbiyah Imaniyah and Islamiyah; 3) utilizing technological media, and 4) referencing the Qur'an and Hadith. The researchers concluded that implementing Islamic-based STEAM learning in Islamic Kindergarten/Raudhatul Athfal is characterized by reoccurring themes, which are subsequently translated into STEAM learning activities. The researchers urge Islamic Kindergarten/Raudhatul Athfal teachers to incorporate Islamic values throughout all STEAM curriculum components continuously. </em><strong></strong></p>
Assessing ChatGPT Responses to Common Patient Questions Regarding Total Hip Arthroplasty
Authors: Mika Aleksander P. , Martin J. Ryan , Engstrom Stephen M. , Polkowski Gregory G. , Wilson Jacob M. 
Published: July 2023

Background:
The contemporary patient has access to numerous resources on common orthopaedic procedures before ever presenting for a clinical evaluation. Recently, artificial intelligence (AI)-driven chatbots have become mainstream, allowing patients to engage with interfaces that supply convincing, human-like responses to prompts. ChatGPT (OpenAI), a recently developed AI-based chat technology, is one such application that has garnered rapid growth in popularity. Given the likelihood that patients may soon call on this technology for preoperative education, we sought to determine whether ChatGPT could appropriately answer frequently asked questions regarding total hip arthroplasty (THA).

Methods:
Ten frequently asked questions regarding total hip arthroplasty were posed to the chatbot during a conversation thread, with no follow-up questions or repetition. Each response was analyzed for accuracy with use of an evidence-based approach. Responses were rated as “excellent response not requiring clarification,” “satisfactory requiring minimal clarification,” “satisfactory requiring moderate clarification,” or “unsatisfactory requiring substantial clarification.”

Results:
Of the responses given by the chatbot, only 1 received an “unsatisfactory” rating; 2 did not require any correction, and the majority required either minimal (4 of 10) or moderate (3 of 10) clarification. Although several responses required nuanced clarification, the chatbot’s responses were generally unbiased and evidence-based, even for controversial topics.

Conclusions:
The chatbot effectively provided evidence-based responses to questions commonly asked by patients prior to THA. The chatbot presented information in a way that most patients would be able to understand. This resource may serve as a valuable clinical tool for patient education and understanding prior to orthopaedic consultation in the future.
Opioid-Sparing Strategies in Arthroscopic Surgery
Authors: Ekhtiari Seper , Nucci Nicholas , Uddin Fares , Albadran Adeeba , Gazendam Aaron Michael , Bhandari Mohit , Khan Moin 
Published: July 2023

Background:
Opioid overprescription is a problem in orthopaedic surgery. Arthroscopic surgery, given its minimally invasive nature, represents an opportunity to minimize opioid prescription and consumption by using effective pain management adjuncts. Thus, the primary question posed in this study was which noninvasive pain management modalities can effectively manage pain and reduce opioid intake after arthroscopic surgery.

Methods:
The databases PubMed, MEDLINE, EMBASE, Scopus, and Web of Science were searched on August 10, 2022. Randomized controlled trials (RCTs) evaluating noninvasive pain management strategies in arthroscopy patients were evaluated. Eligible studies were selected through a systematic screening process. Meta-analysis was performed for pain scores and opioid consumption at time points which had sufficient data available.

Results:
Twenty-one RCTs were included, with a total of 2,148 patients undergoing shoulder, knee, and hip arthroscopy. Meta-analysis comparing nonopioid, oral analgesic regimens, with or without patient education components, with the standard of care or placebo demonstrated no difference in pain scores at 24 hours, 4 to 7 days, or 14 days postoperatively. Nonopioid regimens also resulted in significantly lower opioid consumption in the first 24 hours postoperatively (mean difference, −37.02 mg oral morphine equivalents, 95% confidence interval, −74.01 to −0.03). Transcutaneous electrical nerve stimulation (TENS), cryotherapy, and zolpidem were also found to effectively manage pain and reduce opioid use in a limited number of studies.

Conclusions:
A range of noninvasive pain management strategies exist to manage pain and reduce opioid use after arthroscopic procedures. The strongest evidence base supports the use of multimodal nonopioid oral analgesics, with some studies incorporating patient education components. Some evidence supports the efficacy of TENS, cryotherapy, and nonbenzodiazepine sleeping aids. Direction from governing bodies is an important next step to incorporate these adjuncts into routine clinical practice to manage pain and reduce the amount of opioids prescribed and consumed after arthroscopic surgery.

Level of Evidence:

Level II, systematic review and meta-analysis of RCTs. See Instructions for Authors for a complete description of the levels of evidence.
Age-dependent Effect of Vitamin D Supplementation on Musculoskeletal Health in Chronic Spinal Cord Injury Patients: A Pilot Study
Authors: Yang Hea-Eun , An Eui Jin , Choi I Jun , Oh Ji Yeon , Lee Byeong Wook 
Published: July 2023

AbstractStudy designProspective drug-intervention study.ObjectivesTo determine the effect of vitamin D supplementation on changes in body composition associated with musculoskeletal health status in patients with chronic SCI and vitamin D deficiency as a response to age.SettingDepartment of rehabilitation medicine, Veterans Health Service Medical Center.MethodsSeventeen patients with vitamin D insufficiency/deficiency (<30 ng/ml) and chronic SCI were divided into two groups: groups (A) <65 years (n=8) and (B) ≥65 years of age (n=9). Both groups received 800 IU/day cholecalciferol for 12 weeks. Participants body composition at baseline and 12 weeks after treatment were evaluated. We used blood samples to evaluate metabolites related to vitamin D, testosterone (T), lipid profiles, and sex hormone-binding globulin (SHBG). Bioelectrical impedance analysis (BIA) was used to evaluate body composition.ResultsGroup A had significantly better baseline clinical characteristics for all BIA measurements. SHGB was significantly higher in Group B (p=0.003) and albumin was significantly higher in Group A (p=0.000). When comparing pre- to post-treatment, Group A showed a significant improvement in T (p=0.042), total cholesterol (p=0.035), and triglyceride (p=0.025) levels, whereas Group B significantly increased vitamin D (p=0.038) and protein mass (PM) (p=0.034) levels.ConclusionsThis study confirmed that addressing vitamin D deficiency in patients with SCI had different effects in young and older adults, with both groups showing positive changes in body composition. Particularly, the increase in PM on BIA measurements in elderly patients at high risk of sarcopenia was encouraging.
Assessing Fishery Households Welfare in Indonesia: Panel Spatial Durbin Model Approach
Authors: Harsono Iwan , Sukiyono Ketut , Mulana Lalu Yuriade 
Published: July 2023

Abstract

The welfare of fishermen, indicated by the value of NTN, is the government's focus in supporting economic growth and national development. The NTN or Nilai Tukar Nelayan (Fihermen Exchange Rate), is estimated based on the prices of goods and services in terms of production, costs and household consumption.. On the other hand, the government needs to recognize how macroeconomic assumptions affect the welfare of fishermen in Indonesia as a basis for budget planning and national development programs. Therefore, this study is aimed at- comprehensively analyzing the welfare of fishermen in Indonesia using a spatial Durbin panel model approach. Provincial (spasial) secondary data from 2020–2022 involving variables of Fishermen's Exchange Rates, Human Development, Population Density, inflation, agricultural sector labor, and average daily wages are used for thi study.. From the results of selecting the best model human capital (IPM) and inflation have a significant positive effect on fishery household welfare in Indonesia, while other factors are not... Further goverment interventions are further required especially to improve fishermen skill and inovations, development disparities as well as inflation controls.
Synergistic Effects of Graphite and Carbon Nanotube Hybrid Fillers on Key Properties of Epoxidized Natural Rubber Nanocomposites
Authors: Pichaiyut Skulrat , Kitisavetjit Wasuthon , Nakason Charoen 
Published: July 2023

Abstract

This study investigates the preparation and characterization of epoxidized natural rubber (ENR) nanocomposites using graphite (GP), carbon nanotubes (CNTs), and CNTs/GP hybrid fillers. The results demonstrate that both gum and filled ENR compounds exhibit a reversion curve due to the breaking of weak -O-O- linkages. Furthermore, increasing GP loadings in ENR-GP and ENR-CNTs/GP hybrid composites lead to elevated cure curves and torque differences, indicating higher crosslink density and stiffness of the vulcanizates. These changes are attributed to the increasing chemical interaction between polar functional groups in ENR molecules and nanofiller surfaces, as confirmed by FTIR analysis. The analysis demonstrates a decrease in OH and epoxide groups, along with an increase in ether linkages. Moreover, ENR-CNTs/GP hybrid composites exhibit even higher curing curves, torque differences, Payne effect, total bound rubber content, electrical conductivity, and dielectric constant due to finer filler dispersion and distribution. This results in the formation of interconnected infinite networks that rapidly reach the percolation threshold concentration. Additionally, the formation of CNTs-GP-CNT connections enhances mechanical strength, heat conduction, and the tunneling effect of electrons. These findings confirm the synergistic effects of graphite and carbon nanotube hybrid fillers on key properties in ENR-CNTs/GP hybrid nanocomposites, indicating their potential applications in various fields.