bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible circularly polarized CPW antenna for X-band: design, simulation, and experimental validation
Authors: D Rajesh Kumar , Vishnulakshmi K , K G Sujanth Narayan , G Venkat Babu 
Published: January 2025

Abstract
This paper presents the design and analysis of a circularly polarized coplanar waveguide (CPW) antenna specifically tailored for X-band applications. The antenna, with compact dimensions of 27 mm × 28 mm, is fabricated on a flexible 0.1 mm thick polyimide substrate. It operates effectively within the frequency range of 10.5 GHz to 12 GHz. To enhance performance metrics such as gain and radiation characteristics, two complementary split-ring resonators (CSRRs) are integrated into the radiating patch. Comprehensive simulations were conducted, followed by the fabrication and experimental testing of the antenna. The results indicate a high degree of agreement between the simulated and measured performance parameters. The antenna achieves a gain of up to 6 dBi, with an axial ratio maintained below 3 dB across the operating frequency band, signifying excellent circular polarization characteristics. These findings underscore the potential of the proposed CPW antenna design as a highly efficient solution for X-band applications, offering notable improvements in gain and axial ratio performance. This work contributes to the development of advanced antenna technologies suitable for modern communication systems operating in the X-band spectrum.
Toward a Definition of Mexican Canto Nuevo
Authors: Palomares-Salas Claudio 
Published: January 2025

Abstract
Chapter 2 explores various features crucial to comprehending Mexican Canto Nuevo from a broader perspective. These include the movement’s nomenclature and temporality, the positionality of its members, and the critical concept of folklorization, which is essential to understanding Canto Nuevo’s approach to traditional Mexican and Latin American music. It also discusses the Marxist/humanist values that sustained the movement ideologically and some of the shared features among its members, which positioned themselves collectively in response to the social, cultural, and political events shaping Mexico and Latin America in the 1960s–1980s. Finally, it studies the six themes dominating the movement’s lyrical production: history, social and political issues, armed struggle, humor, love, and children’s topics.
Consolidation (1977–1981)
Authors: Palomares-Salas Claudio 
Published: January 2025

Abstract
Chapter 6 examines Canto Nuevo’s consolidation as a cultural force in Mexico from 1977 to 1981. It discusses the substantial support received through official organizations, reviews the two Encuentros de la Canción Política in 1977–1978, and explores how Canto Nuevo went beyond the peñas and embarked on a series of massive concerts, particularly the Festivales de Oposición, which became emblematic of the movement. It discusses the participation of some Canto Nuevo artists in the Onceavo Festival de la Juventud y los Estudiantes held in Cuba in 1978 and the 1981 Canto Nuevo contest organized by Canal 13. It also reviews Gabino Palomares’s La maldición de Malinche (1977), discusses the group Sanampay, and briefly surveys the work of Guadalupe Pineda, Eugenia León, and Tania Libertad. Finally, the chapter explores Canto Nuevo’s solidarity activity with Central American revolutionary movements and discusses the emergence of the record label Pentagrama.
Brain aging rejuvenation factors in adults with genetic and sporadic neurodegenerative disease
Authors: Casaletto Kaitlin B , Saloner Rowan , Kornak John , Staffaroni Adam M , Villeda Saul , Paolillo Emily , VandeBunte Anna M , Cadwallader Claire J , Lario Lago Argentina , Webb Julia , Chen Coty , Rascovsky Katya , Miyagawa Toji , Ramos Eliana Marisa , Masdeu Joseph C , Pantelyat Alexander , Tartaglia Maria Carmela , Bozoki Andrea , Pressman Peter S , Rademakers Rosa , Kremers Walter , Darby Ryan , Younes Kyan , Pascual Belen , Ghoshal Nupur , Lapid Maria , Mackenzie Ian R A , Li Jingyao , Hsiung Ging-Yuek Robin , Hall Jacob N , Yutsis Maya V , Litvan Irene , Henderson Victor W , Sivasankaran Rajeev , Worringer Katie , Domoto-Reilly Kimiko , Snyder Allison , Loureiro Joseph , Kramer Joel H , Heuer Hilary , Forsberg Leah K , Rosen Howard J , Boeve Bradley , Rojas Julio C , Boxer Adam L 
Published: January 2025

Abstract
The largest risk factor for dementia is age. Heterochronic blood exchange studies have uncovered age-related blood factors that demonstrate ‘pro-aging’ or ‘pro-youthful’ effects on the mouse brain. The clinical relevance and combined effects of these factors for humans is unclear. We examined five previously identified brain rejuvenation factors in cerebrospinal fluid of adults with autosomal dominant forms of frontotemporal dementia and sporadic Alzheimer’s disease. Our frontotemporal dementia cohort included 100 observationally followed adults carrying autosomal dominant frontotemporal dementia mutations (Mage = 49.6; 50% female; 43% C9orf72, 24% GRN, 33% MAPT) and 62 non-carriers (Mage = 52.6; 45% female) with cerebrospinal fluid analysed on Somascan, and longitudinal (Mvisits = 3 years, range 1–7 years) neuropsychological and functional assessments and plasma neurofilament light chain. Our Alzheimer’s disease cohort included 35 adults with sporadic Alzheimer’s disease (Mage = 69.4; 60% female) and 56 controls (Mage = 68.8, 50% female) who completed the same cerebrospinal fluid and clinical outcome measures cross-sectionally. Levels of C-C motif chemokine ligand 11, C-C motif chemokine ligand 2, beta-2-micorglobulin, bone gamma-carboxyglutamate protein (aka Osteocalcin) and colony stimulating factor 2 in cerebrospinal fluid were linearly combined into a composite score, with higher values reflecting ‘pro-youthful’ levels. In genetic frontotemporal dementia, higher baseline cerebrospinal fluid rejuvenation proteins predicted slower decline across cognitive, functional, and neurofilament light chain trajectories; estimates were similar across genotypes. In transdiagnostic analyses, higher cerebrospinal fluid rejuvenation proteins associated with better functional, cognitive, and neurofilament light chain outcomes in adults with sporadic Alzheimer’s disease. Proteins with pre-clinical evidence for brain rejuvenation show translational clinical relevance in adults with Alzheimer’s disease and related dementias and warrant further investigation.
The empowering influence of air-liquid interface culture on skin organoid hair follicle development
Authors: Sun Jane , Ahmed Imaan , Brown Jason , Khosrotehrani Kiarash , Shafiee Abbas 
Published: January 2025

Abstract

Background
Rodent models have been widely used to investigate skin development, but do not account for significant differences in composition compared to human skin. On the other hand, two-dimensional and three-dimensional engineered skin models still lack the complex features of human skin such as appendages and pigmentation. Recently, hair follicle containing skin organoids (SKOs) with a stratified epidermis, and dermis layer have been generated as floating spheres from human-induced pluripotent stem cells (hiPSCs).

Methods
The current study aims to investigate the generation of hiPSCs-derived SKOs using an air-liquid interface (ALI) model on transwell membranes (T-SKOs) and compares their development with conventional floating culture in low-attachment plates (F-SKOs).

Results
Mature SKOs containing an epidermis, dermis, and appendages are created in both T-SKO and F-SKO conditions. It was found that the hair follicles are smaller and shorter in the F-SKO compared with T-SKOs. Additionally, the ALI conditions contribute to enhanced hair follicle numbers than conventional floating culture.

Conclusions
Together, this study demonstrates the significant influence of transwell culture on the morphogenesis of hair follicles within SKOs and highlights the potential for refinement of skin model engineering for advancing dermatology and skin research.
An aortic root abscess mimic identified by multi-disciplinary imaging review: a case report
Authors: Caceres Juan , Sulaiman Abdulbaset , Edwards Mark , Zhou Shiwei , Kurz Sarah , Raglow Zoe , Hamilton Barbara , Harris Andrew W 
Published: January 2025

Abstract

Background
While echocardiography and cardiac positron emission tomography (PET) can aid in the diagnosis of prosthetic valve endocarditis (PVE), post-operative changes can lead to false-positive imaging findings. We report a case of a patient with an aortic valve prosthesis with remnant BioGlue deposits mimicking a para-valvular abscess on imaging in the setting of suspected PVE.

Case summary
A 67-year-old man presented with 2 days of fever, chills, and altered mentation. He had a history of two prior aortic root replacements—19 and 4 years prior to his presentation. He had blood cultures that were persistently positive for Pseudomonas aeruginosa. Initial transoesophageal echocardiogram (TEE) was notable for a thickening of the posterior aortic root thought to be consistent with post-surgical changes. Cardiac PET showed significant uptake around the prosthetic aortic valve, concerning for a para-valvular abscess. However, given the patient’s high risk for re-do surgery, clearance of blood cultures, and preserved valve function, our multi-disciplinary endocarditis team (MET) recommended non-surgical management and close follow-up. After 6 weeks of appropriate antibiotics, a TEE demonstrated concern for an evolving para-valvular abscess. The MET performed extensive review of his prior surgical interventions and cardiac imaging, revealing the previous use of surgical BioGlue and stability in the aortic root on imaging, consistent with non-infectious post-surgical changes, and conservative management was recommended.

Discussion
Thorough review of prior interventions and serial imaging in patients with suspected PVE through a multi-disciplinary team approach is essential in elucidating the complete, often complex, clinical picture and recommending the most appropriate management.
Systemic Glucose Homeostasis Requires Pancreatic but Not Neuronal ATP-sensitive Potassium Channels
Authors: Li Athena H , Tsai Wen-Sheng , Tsai Wen-Hao , Yang Shi-Bing 
Published: January 2025

Abstract
The adenosine triphosphate (ATP)-sensitive potassium (KATP) channels, composed of Kir6.2 and sulfonylurea receptor 1 (SUR1) subunits, are essential for glucose homeostasis. While the role of pancreatic KATP channels in regulating insulin secretion is well-documented, the specific contributions of neuronal KATP channels remain unclear due to challenges in precisely targeting neuronal subpopulations. In this study, we utilized a Kir6.2 conditional knockout mouse model to distinguish the roles of KATP channels in different cell types. Our findings demonstrate that deletion of neuronal KATP channels does not impair glucose homeostasis, as glucose-sensing neurons retained their responsiveness despite the absence of functional KATP channels. In contrast, the deletion of KATP channels in pancreatic β cells led to significant hyperglycemia and glucose intolerance, indicating unstable blood glucose levels under varying physiological conditions. Importantly, we showed that restoring KATP channel function exclusively in pancreatic β cells within a global Kir6.2 knockout background effectively reversed glucose regulation defects. This underscores the critical role of pancreatic KATP channels in maintaining systemic glucose homeostasis. Our results challenge the previous hypothesis that neuronal KATP channels are essential for glucose regulation, suggesting that their primary function may be neuroprotective rather than homeostatic. These findings highlight pancreatic KATP channels as key regulators of glucose balance and potential therapeutic targets for correcting glucose dysregulation.
Effect of sodium alginate-bentonite nanocomposite films enriched with Satureja hortensis essential oil on extending shelf-life of rainbow trout fillets
Authors: Baran Alper , Nadaroglu Hayrunnisa , Gelen Sevda Urcar 
Published: January 2025

Abstract
This study evaluated the effects of Satureja hortensis essential oil (SHEO)-enriched sodium alginate-bentonite nanocomposite films on the quality of rainbow trout (Oncorhynchus mykiss) fillets during 15 days of refrigerated storage at 4 ± 1 °C, with analyses conducted on days 0, 3, 6, 9, and 15. Five film formulations were prepared: sodium alginate alone (C), sodium alginate with bentonite nanoclay (CN), and sodium alginate combined with SHEO at 0.5%, 1%, and 1.5% concentrations (CN0.5, CN1, CN1.5). SHEO addition improved film properties, with thickness increasing from 0.225 ± 0.013 cm in the control to 0.245 ± 0.014 cm in CN1.5 and tensile strength peaking at 5.37 ± 0.15 MPa in CN0.5. The CN1.5 group exhibited superior preservation effects, maintaining total viable counts at 4.58 log CFU/g compared to 6.88 log CFU/g in the control by day 15. Pseudomonas spp., coliforms, lactic acid bacteria, and psychrotrophic bacterial counts were significantly reduced. Lipid oxidation was minimized, with TBARS values of 0.8 mg MDA/kg in CN1.5 compared to 2.38 mg MDA/kg in the control. Additionally, TVB-N levels were maintained at 15.4 mg N/100 g in CN1.5, while they reached 28.4 mg N/100 g in the control. These results highlight the potential of SHEO-enriched sodium alginate-bentonite nanocomposite films, particularly CN1.5, in extending the freshness and shelf life of rainbow trout fillets under refrigerated conditions.
Use of potassium hydroxide as a source of nutrients in the composition of food supplements
Authors: Zovi Andrea , Ferrara Francesco 
Published: January 2025

Abstract
In recent years, diet and nutrition have become a primary focus of public health worldwide. Food supplements (FS), used to complement common diets, are a significant and highly marketed category of food products. This has positioned healthcare professionals and public decision makers to play critical roles in their distribution and monitoring. Following a serious case of intoxication due to the ingestion of potassium hydroxide (KOH) as a nutrient source in a food supplement, technical opinion has been applied to admissible levels of vitamins and minerals in such products. KOH, known for its high potential Hydrogen (pH) and caustic properties, poses safety risks if not properly diluted. EU Regulation 1169/2011 stipulates minimum significant quantities for nutrients, including potassium, which must not exceed certain levels to ensure safety. The use of KOH as the sole potassium source in the form of powders has been shown to create strong alkalinity, posing risks when dissolved in water for human consumption. Safer alternative potassium forms are available for food supplements. This underscores the need for continuous regulatory oversight and greater involvement of healthcare professionals to ensure consumer safety, given the broad variability in supplement formulations and their increasing market share.
Association Between Herpes Simplex Virus Type 2 and High-Risk Human Papillomavirus Infections: A Population Study of the National Health and Nutrition Examination Survey, 2009–2016
Authors: Liu Chuqi , Guo Yongzhen , Wang Lulu , Guo Ruixia , Lei Dongmei 
Published: January 2025

Abstract

Background
Human papillomavirus (HPV) is a leading cause of cervical cancer, with 14 subtypes classified as high-risk HPV (HR-HPV). Despite the availability of vaccines, certain regions still experience limited access. Herpes simplex virus type 2 (HSV-2), a common sexually transmitted infection, is hypothesized to increase the risk of HR-HPV infections. This study aims to individually analyze whether HSV-2 infection increases the risk of each HR-HPV infection in a representative sample of American adults.

Methods
Data were derived from the National Health and Nutrition Examination Survey from 2009 to 2016, involving 4076 female participants. The study utilized logistic regression to estimate the link between HSV-2 infection and HR-HPV infection. We also conducted a stratified analysis to evaluate the impact of HSV-2 on HR-HPV infection in different subgroups.

Results
After adjustment, the odds of having HR-HPV infection were 1.46 (95% CI, 1.24–1.71) for those with HSV-2 infection. Moreover, women with HSV-2 infection had higher odds of HPV-18 (odds ratio, 3.01; 95% CI, 2.05–4.41) and HPV-58 (OR, 2.05; 95% CI, 1.52–3.32) infection even after adjusting for potential confounding factors. The results remain significant in subgroup analysis and in the interaction test.

Conclusions
The study found a significant association between HSV-2 infection and HR-HPV infection, particularly with HPV-18 and HPV-58, highlighting the importance of preventing HSV infection and advocating for early vaccination with an HPV vaccine for those vulnerable to HSV infection. Further prospective studies are needed to validate causal associations and elucidate the underlying mechanisms.
A Step Toward Formalising Visual Data Analysis Practices in Human Computer Interaction
Authors: Sturdee Miriam 
Published: January 2025

Abstract
Visual data is an integral part of qualitative research, yet it is not always clear to researchers how to use or interpret it once gathered. Existing methods for qualitative data analysis largely rely on textual approaches such as thematic analysis, or grounded theory. Open coding is a term that is frequently used to describe a analysis that follows a logical—yet undocumented—process, but these can often be applied ad hoc, and are necessarily created after the fact of data collection. Researchers often develop their own ways of interrogating visual data, but can struggle to prove the legitimacy of not employing an existing approach. This article outlines a proven and replicable process for the analysis of static visual imagery that has been developed by the author and utilised together with research collaborators over a seven year period. The approach, which I call Annotated Visual Analysis (AVA), can be used for sketched or artistic data from participants or in first person, subjective research, in order to generate insight, gather requirements or confirm hypotheses. Here, I outline five case studies using the approach in differing contexts, in order to demonstrate its applicability, and outline the process and guidelines so that other researchers might employ the method. I also discuss the need for other researchers using visual methods to share and consolidate their forms of analysis to develop knowledge for use by others in the field.
Intrathecal Baclofen Pump Wean and Risk of Exposure in a Large Total Body Surface Area Burn Wound Patient: A Case Report
Authors: Lautenslager Lauren A , Cullom Melissa E , Bedgood Deidra B , Boyd Allison N , Spera Leigh J 
Published: January 2025

Abstract
Burn injuries in patients with significant preexisting medical conditions provide unique challenges in both medical management and surgical planning. Spasticity, if left untreated, can be one of the most disabling consequences of a neurologic injury. Treatment is largely dependent on pharmacologic management with antispasmodic agents such as baclofen. Baclofen’s effectiveness when taken orally is often limited by its systemic side effects, which mostly affect the CNS. Intrathecal baclofen (ITB) can circumvent these intolerable adverse effects while achieving symptom relief via a more targeted therapeutic route. However, abrupt cessation of chronic baclofen use can precipitate an acute life-threatening withdrawal syndrome. We present a case of a 47-year-old female who sustained 54% TBSA full-thickness flame burns to the circumferential bilateral lower extremities, left arm, left anterior and posterior trunk, flank, and perineum. She had a premorbid C5 spinal cord injury resulting in spastic paraplegia for which she had an ITB pump implanted into her left abdominal wall for symptom management. This pump was directly beneath her operative burn wounds. We discuss the complex issues that were encountered throughout her care related to medication reservoir supply, life-threatening risk of baclofen withdrawal, pain-specialist availability, medical-legal barriers, and the multi-staged surgical plan for coverage, balancing proper wound debridement with risk of device exposure and infection. To our knowledge, this is the only case report detailing the cohort of obstacles that may be associated with these devices, specifically with burn patients.
Latitudinal variation in leaf functional traits of an invasive salt-marsh plant and its relationship with growth performance
Authors: Guo Yangping , Chen Xincong , Wu Fujia , Liu Wenwen , Zhang Yihui 
Published: January 2025

Abstract
Leaf functional traits reveal the ecological strategies of plants and affect growth and distribution. Variation in leaf traits was usually documented across species in terrestrial ecosystems, studying in wetlands can advance the understanding about leaf trait variation along environmental gradients. Intraspecific study contributes to explore trait variation and underlying mechanism. Marine coastal wetlands have become hot spots for studying trait variation. Invasive Spartina alterniflora distributed along China’s coastline, is an ideal species for studying leaf traits variation. We determined geographical variation and abiotic drivers in six leaf functional traits, and explored the roles of phenotypic plasticity and genetic differentiation through a 2-year common garden experiment. We detected relationships between leaf traits and growth performance in field and common garden. All leaf traits exhibited significant geographical variation, which were affected by both climatic and sedimentary variables. Common garden experiment exhibited the trait-dependent response, different leaf traits showed various degrees of plastic response or genetic differentiation. Variation in leaf size, leaf thickness, and specific leaf area displayed genetic differentiation, while variation in leaf density and leaf dry matter content exhibited plastic response. Leaf size and thickness positively correlated with growth performance in field and common garden. Our study advances the understanding about leaf trait variation in the terrestrial ecosystems. Multiple abiotic variables shape the latitudinal patterns in leaf traits. Resource acquisition at high latitudes in the northern hemisphere contributes to great growth performance of S. alterniflora, which might promote expansion northward, whereas the resource conservation at low latitudes might hinder expansion southward.
SN 2023xwi: Forbidden line emission in the peak spectrum of a Ca-strong transient
Authors: Touchard-Paxton C-G , Frohmaier C , Pursiainen M , Sullivan M , Polin A , Dimitriadis G , Galbany L , Killestein T L , Kumar A , Lyman J 
Published: January 2025

Abstract
We present an extensive optical photometric and spectroscopic investigation into the calcium-rich supernova (SN) – SN2023xwi. Observations from a variety of ground-based telescopes follow the SN from 8 days pre-peak brightness to 87 days post-peak, covering both early-time (photospheric) and late-time (nebular) phases of the supernova. Objects of this class are characterised by nebular spectra that are dominated by [Ca II] λλ 7291, 7324 emission. SN 2023xwi displays a unique peculiarity in that its forbidden [Ca II] feature is visible in its peak photospheric spectrum – far earlier than expected in current models. This is one of the strongest and earliest detections of this feature in Ca-rich SNe in photospheric-phase spectra. We investigate the velocity evolution of this spectral feature and show that it cannot be easily explained by conventional progenitor systems. From our observations, we propose a SN progenitor embedded in an environment polluted by a recurrent He-nova AM CVn system.