bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three‐dimensional sector‐wise golden angle–improved k‐space uniformity after electrocardiogram binning
Authors: Fyrdahl Alexander , Ullvin Amanda , Ramos Joao G. , Seiberlich Nicole , Ugander Martin , Sigfridsson Andreas 
Published: May 2023

PurposeTo develop and evaluate a 3D sector‐wise golden‐angle (3D‐SWIG) profile ordering scheme for cardiovascular MR cine imaging that maintains high k‐space uniformity after electrocardiogram (ECG) binning.MethodCardiovascular MR (CMR) was performed at 1.5 T. A balanced SSFP pulse sequence was implemented with a novel 3D‐SWIG radial ordering, where k‐space was divided into wedges, and each wedge was acquired in a separate heartbeat. The high uniformity of k‐space coverage after physiological binning can be used to perform functional imaging using a very short acquisition. The 3D‐SWIG was compared with two commonly used 3D radial trajectories for CMR (i.e., double golden angle and spiral phyllotaxis) in numerical simulations. Free‐breathing 3D‐SWIG and conventional breath‐held 2D cine were compared in patients (n = 17) referred clinically for CMR. Quantitative comparison was performed based on left ventricular segmentation.ResultsNumerical simulations showed that 3D‐SWIG both required smaller steps between successive readouts and achieved better k‐space sampling uniformity after binning than either the double golden angle or spiral phyllotaxis trajectories. In vivo evaluation showed that measurements of left ventricular ejection fraction calculated from a 48 heart‐beat free‐breathing 3D‐SWIG acquisition were highly reproducible and agreed with breath‐held 2D‐Cartesian cine (mean ± SD difference of −3.1 ± 3.5% points).ConclusionsThe 3D‐SWIG acquisition offers a simple solution for highly improved k‐space uniformity after physiological binning. The feasibility of the 3D‐SWIG method is demonstrated in this study through whole‐heart cine imaging during free breathing with an acquisition time of less than 1 min.
A comprehensive study demonstrating the influence of the solvent composition on the phytotoxicity of compounds, as exemplified by 2,4‐D‐based ILs with a choline‐type cation
Authors: Niemczak Michał , Stachowiak Witold , Kaczmarek Damian Krystian , Grzanka Monika , Sobiech Łukasz 
Published: May 2023

BackgroundGrowing concern for the protection of the environment and existing ecosystems has resulted in increasing consideration of phytotoxicity tests as valid ecotoxicological indicators of the potential hazards of the use of ionic liquids (ILs) or any other chemical. The objective of this study was to gain a detailed understanding of the influence of the solvent composition of spray solutions on the phytotoxic effect of foliar application of ionic pairs with weak (choline 2,4‐dichlorophenoxyacetate, [Chol][2,4‐D]), medium (N‐hexylcholine 2,4‐dichlorophenoxyacetate, [C6Chol][2,4‐D]) and good (N‐dodecylcholine 2,4‐dichlorophenoxyacetate, [C12Chol][2,4‐D]) surface‐active properties.ResultsExperimental results unambiguously demonstrated that the biological activity of the test salt solutions, particularly [Chol][2,4‐D] and [C6Chol][2,4‐D], can be strongly affected by the addition of an organic solvent, such as methanol, ethanol, dimethylformamide (DMF) or dimethylsulfoxide (DMSO) compared to solutions in pure water. However, the observed tendency is less pronounced for the compound exhibiting good surface activity, [C12Chol][2,4‐D].ConclusionsThe collected findings show that caution is warranted in the exploitation or modification of methodologies for assessing phytotoxicity to ensure the reliable interpretation of obtained results for environmental risk assessment or building quantitative structure–activity relationship (QSAR) models. © 2023 Society of Chemical Industry.
Toumeyella parvicornis versus endotherapic abamectin: three techniques, 1 year after
Authors: Di Sora Nicolò , Rossini Luca , Contarini Mario , Mastrandrea Giovanni , Speranza Stefano 
Published: May 2023

AbstractBackgroundToumeyella parvicornis is an invasive soft scale insect native to North America that is rapidly spreading in Italy and France, provoking severe infestations on Pinus pinea L. To date, the control of this pest is entrusted to three endotherapic techniques whose short‐term efficacy is partially known. No information on long‐term efficacy is currently available, although fundamental. This work aims to report on the long‐term effect that abamectin‐based insecticides, injected with the three different techniques, have on adult female populations.ResultsThe study was carried out in an infested P. pinea forest in the area of Rome, Italy. Results showed that the tested methods had a similar long‐term effect, and only in one case there were differences with the untreated control. Multiresidue analysis reported a zero level of abamectin in plant tissues 14 months apart from injection, except for one treatment where pesticide concentration was just above the limit of quantification.ConclusionsThis study represents the first long‐term evaluation about endotherapic control strategy against T. parvicornis. In fact, the pest may quickly bring the death and fall of the stone pines, representing a concerning risk for citizens, however, control actions to manage it are still partially known and deserve more in‐depth investigations. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Frequency and spatial distribution of knock‐down resistance (kdr) to pyrethroids in multiple oilseed rape pest species of the genus Ceutorhynchus
Authors: Daum Eve , Brandes Meike , Heimbach Udo , Zimmer Christoph , Slater Russell , Elias Jan 
Published: May 2023

AbstractBackgroundThe protection of European oilseed rape (OSR) from damaging insects relies on pyrethroid insecticides, but the development of resistance in key coleopteran pests such as the pollen beetle (Brassicogethes aeneus) and the cabbage stem flea beetle (Psylliodes chrysocephala) has resulted in reduced effectiveness of these insecticides. The sodium channel gene mutation L1014F knock‐down resistance (kdr) is a contributing factor in resistance to pyrethroids in B. aeneus and P. chrysocephala, but little is known about the status of resistance in weevils of the genus Ceutorhynchus (Coleoptera: Curculonidae). Therefore, the present study investigated pyrethroid susceptibility and the presence of the kdr mutation in four Ceutorhynchus species.ResultsThe kdr mutation in either its heterozygous or homozygous form was found in all investigated Ceutorhynchus species (C. picitarsis, C. pallidactylus, C. napi and C. obstrictus). Samples where pyrethroids in bioassays still provided control at 100% field rate or below contained kdr at frequencies of ≤12.5%, whilst bioassays using 100% field rate that did not control Ceutorhynchus populations contained homozygous resistant individuals at frequencies of greater than 55%. Field sampling demonstrated that kdr frequencies in populations of C. picitarsis and C. obstrictus collected from across France and Germany ranged from 0 to 100%.ConclusionThe present study demonstrated the potential of all four Ceutorhynchus species tested to develop pyrethroid resistance via the L1014F (kdr) mutation. Although kdr frequency varies among species and geographic locations, the risk of loss of pyrethroid insecticide effectiveness is high. Integration of other control tools for resistance management is therefore needed. © 2023 Society of Chemical Industry.
The ryanodine receptor mutation I4728M confers moderate‐level resistance to diamide insecticides in Spodoptera litura
Authors: Mei Wenjuan , Zuo Yayun , Su Ting , Yuan Jing , Wu Yidong , Yang Yihua 
Published: May 2023

AbstractBackgroundThe common cutworm, Spodoptera litura (Fabricius), is one of the most widespread and destructive polyphagous pests in tropical and subtropical Asia. S. litura has evolved resistance to different insecticides, including diamide insecticides. Here, we identified a ryanodine receptor (RyR) mutation (I4728M) associated with target site resistance to diamides in a field‐collected population of S. litura. The contribution of this mutation to diamide resistance was investigated through establishing a near‐isogenic resistant strain of S. litura.ResultsThe ND21 population of S. litura, collected from Ningde, Fujian province of China in 2021, exhibited 130.6‐fold resistance to chlorantraniliprole compared to the susceptible NJ‐S strain. S. litura RyR mutation I4728M, corresponding to Plutella xylostella RyR I4790M, was identified in the ND21 population. SlRyR I4728M mutation of ND21 was introgressed into a susceptible background strain (NJ‐S) with marker‐assisted backcrossing. The introgressed strain named ND21‐R, which was homozygous for the mutant 4728M allele, shared about 94% of the genetic background with the NJ‐S strain. ND21‐R strain showed moderate levels of resistance to two anthranilic diamides (19.1‐fold to chlorantraniliprole, 19.7‐fold to cyantraniliprole) and the phthalic diamide flubendiamide (23.4‐fold). Genetic analysis showed that chlorantraniliprole resistance was autosomal, incompletely recessive and tightly linked with SlRyR I4728M mutation in the introgressed ND21‐R strain of S. litura.ConclusionIdentification of the I4728M mutation and its contribution to diamide resistance in S. litura will help develop allelic discrimination assays for resistance monitoring and guide resistance management practices for diamides in S. litura. © 2023 Society of Chemical Industry.
Strategic leadership in liminal space: Framing exploration of digital opportunities at hierarchical interfaces
Authors: Putra Fathiro H. R. , Pandza Krsto , Khanagha Saeed 
Published: May 2023

AbstractResearch SummaryWe investigate how strategic leaders of an incumbent firm frame exploration of digital opportunities at the interfaces of organizational hierarchy. Digital technologies create an unbounded array of opportunities that may pose challenges to the strategic coherence of corporate entrepreneurship activity. Our analysis reveals that top management teams (TMTs) adopt a paradoxical framing of exploration, thereby creating a liminal space with unstable boundaries between exploration activities aligned with core resources (i.e., convergent) and those perceived as divergent. We show that middle managers (MMs) skillfully navigate this space by combining framing with substantive and symbolic actions to blur the boundaries of exploration. Drawing on our findings, we theorize the role of framing at the interfaces between the TMT and MMs in setting boundaries for exploration.Managerial SummaryThe process of digital transformation can be overwhelming for established companies as managers encounter a myriad of new opportunities. Our study of a large telecommunications company found that both senior and MMs play important roles in guiding the development of new digital businesses. Senior managers encourage creative thinking and promote exploring multiple innovation opportunities. However, they also set boundaries to prevent innovation activities from becoming too risky by venturing into very distant domains. This contradictive requirement creates a “gray zone” for MMs to imaginatively use their skills to navigate restrictions without compromising exploration of new opportunities. This approach involves both top‐down and bottom‐up communication between senior and MMs that helps avoid short‐sightedness and overspending when it comes to innovating with digital technologies.
Regulating Crystallization and Lead Leakage of Perovskite Solar Cell Via Novel Polyoxometalate‐Based Metal–Organic Framework
Authors: Dong Yayu , Zhang Jian , Wang Wei , Hu Boyuan , Xia Debin , Lin Kaifeng , Geng Lin , Yang Yulin 
Published: May 2023

AbstractDespite the unprecedented progress in lead‐based perovskite solar cells (PSCs), the toxicity and leakage of lead from degraded PSCs triggered by deep‐level defects and poor crystallization quality increase environmental risk and become a critical challenge for eco‐friendly PSCs. Here, a novel 2D polyoxometalate (POM)‐based metal–organic framework (MOF) (C5NH5)4(C3N2H5)2Zn3(H8P4Mo6O31)2·2H2O (POMOF) is ingeniously devised to address these issues. Note that the integration of POM endows POMOF with great advantages of electrical conductivity and charge mobility. Ordered POMOF induces the crystallization of high‐quality perovskite film and eliminates lead‐based defects to improve internal stability. The resultant PSCs achieve a superior power conversion efficiency (23.3%) accompanied by improved stability that maintains ≈90% of its original efficiency after 1600 h. Meanwhile, POMOF with phosphate groups effectively prevents lead leakage through in situ chemical anchoring and adsorption methods to reduce environmental risk. This work provides an effective strategy to minimize lead‐based defects and leakage in sustainable PSCs through multi‐functional POM‐based MOF material.
Strategic Fast Induction Heating to Combat Hysteresis Barriers in a Flexible MOF for Rapid CO2Desorption in Biogas Upgrading
Authors: Maity Rahul , Gholami Mohsen , Peter Sunil A. , Schoukens Matthias , Tiriana Segato , Baron Gino V. , Denayer Joeri F. M. 
Published: May 2023

AbstractA major challenge in Cyclic Swing Separation using flexible adsorbents that have high equilibrium CO2 adsorption capacity is their very low‐pressure hysteresis that hinders efficient desorption. Mg‐Gallate MOF is such a flexible adsorbent that only begins to release CO2at its pore closing pressure at 0.08 bar and 30 °C, showing very slow and inefficient desorption in pressure or temperature swing. Therefore, a novel strategy is presented that combines state of art technique Magnetic Induction Heating with a vacuum swing for fast and efficient CO2desorption from flexible adsorbents at a moderately elevated temperature (70 °C).
A General Strategy for Synthesis of Binary Transition Metal Phosphides Hollow Sandwich Heterostructures
Authors: Shi Jinghui , Peng Wei , Yang Yi‐Fei , Li Bo , Nie Jianhang , Wan Hui , Li Yao , Huang Gui‐Fang , Hu Wangyu , Huang Wei‐Qing 
Published: May 2023

AbstractThe hollow sandwich core–shell micro‐nanomaterials are widely used in materials, chemistry, and medicine, but their fabrication, particularly for transition metal phosphides (TMPs), remains a great challenge. Herein, a general synthesis strategy is presented for binary TMPs hollow sandwich heterostructures with vertically interconnected nanosheets on the inside and outside surfaces of polyhedron FeCoPx/C, demonstrated by a variety of transition metals (including Co, Fe, Cd, Mn, Cu, Cr, and Ni). Density functional theory (DFT) calculation reveals the process and universal mechanism of layered double hydroxide (LDH) growth on Prussian blue analog (PBA) surface in detail for the first time, which provides the theoretical foundations for feasibility and rationality of the synthesis strategy. This unique structure exhibits a vertical nanosheet‐shell‐vertical nanosheet configuration combining the advantages of sandwich, hollow and vertical heterostructures, effectively achieving their synergistic effect. As a proof‐of‐concept of their applications, the CoNiPx@FeCoPx/C@CoNiPx hollow sandwich polyhedron architectures (representative samples) show excellent catalytic performance for the oxygen evolution reaction (OER) in alkaline electrolytes. This work provides a general method for constructing hollow‐sandwich micro‐nanostructures, which provides more ideas and directions for design of micro‐nano materials with special geometric topology.
Miniaturized liquid extraction cartridge with a functional porous polytetrafluoroethylene membrane for the determination of formaldehyde in gaseous samples
Authors: Ueta Ikuo , Kawamura Shunsuke , Saito Yoshihiro 
Published: May 2023

AbstractA new miniaturized liquid extraction cartridge equipped with a functional porous polytetrafluoroethylene membrane was developed for the determination of formaldehyde in gaseous samples. The functional polytetrafluoroethylene membrane allows gas to pass through while repelling both water‐based and organic‐based liquids. A derivatization reagent for formaldehyde, 2,4‐dinitrophenylhydrazine, was placed in the cartridge and gaseous samples are collected through the cartridge at 20 ml/min for 30 min. Formaldehyde in the gaseous sample is captured as the corresponding 2,4‐dinitrophenylhydrazine hydrazone, and an aliquot of the sample collection solution can be directly subjected to high‐performance liquid chromatographic analysis. The limit of quantification for the developed method was 5 ng/L formaldehyde in gas with a sampling volume of 600 ml. Proof‐of‐concept for formaldehyde determination in an aqueous sample was demonstrated using the developed cartridge in a purge‐and‐trap extraction setup.
Elucidating the Mechanism of Freeze‐Thaw Driven Content Mixing between Protocells
Authors: Peter Benedikt , Schwille Petra 
Published: May 2023

AbstractModern cells rely on highly evolved protein networks to accomplish essential life functions, including the inheritance of information from parents to their offspring. In the absence of these sophisticated molecular machineries, alternatives were required for primitive protocells to proliferate and disseminate genetic material. Recurring environmental constraints on ancient earth, such as temperature cycles, are considered as prebiotically plausible driving forces capable of shuffling of protocellular contents, thereby boosting compositional complexity. Using confocal fluorescence microscopy, we show that temperature oscillations such as freezing‐thawing (FT) cycles promote efficient content mixing between giant unilamellar vesicles (GUVs) as model protocells. We shed light on the underlying exchange mechanism and demonstrate that transient periods of destabilized membranes enable the diffusion of cargo molecules across vesicle membranes. Furthermore, we determine essential parameters, such as membrane composition, and quantify their impact on the lateral transfer efficiency. Our work outlines a simple scenario revolving around inter‐protocellular communication environmentally driven by periodic freezing and melting of water.
Spirocyclic Iodonium Ylides for Fluorine‐18 Radiolabeling of Non‐Activated Arenes: From Concept to Clinical Research
Authors: Chassé Melissa , Pees Anna , Lindberg Anton , Liang Steven H. , Vasdev Neil 
Published: May 2023

AbstractPositron emission tomography (PET) is a powerful imaging tool for drug discovery, clinical diagnosis, and monitoring of disease progression. Fluorine‐18 is the most common radionuclide used for PET, but advances in radiotracer development have been limited by the historical lack of methodologies and precursors amenable to radiolabeling with fluorine‐18. Radiolabeling of electron‐rich (hetero)aromatic rings remains a long‐standing challenge in the production of PET radiopharmaceuticals. In this personal account, we discuss the history of spirocyclic iodonium ylide precursors, from inception to applications in clinical research, for the incorporation of fluorine‐18 into complex non‐activated (hetero)aromatic rings.
Presenting domain information or self‐exploration to foster hypothesis generation in simulation‐based inquiry learning
Authors: Kuang Xiulin , Eysink Tessa H. S. , de Jong Ton 
Published: May 2023

AbstractThis study investigated the effects of presenting domain information (basic information about the domain) either together with or instead of offering exploratory practice (an exploratory opportunity in a simulation‐based representation of the learning domain) prior to inquiry learning for facilitating students' hypothesis generation and subsequent inquiry processes and their knowledge acquisition. Secondary school students (n = 118) completed a simulation‐based inquiry task on force and motion. They were randomly assigned to one of four conditions: the D + E condition (n = 29), in which domain information and exploratory practice were available; the D condition (n = 30), in which only domain information was available; the E condition (n = 32), in which only exploratory practice was available; or the C condition (n = 27), with no support at all. Students' knowledge was measured with a pre‐ and posttest and a test on knowledge of variables. Inquiry processes were inferred from information students entered in a Hypothesis Scratchpad and an Observation tool, and from a final summary that they had to write. Results indicated that providing students with domain information alone helps to foster their knowledge of variables before generating hypotheses and leads to knowledge acquisition. The results also showed that the opportunity to explore before experimenting does not affect students' inquiry behavior or learning performance, even when combined with providing students with domain information.
“Hice Zoom Con Mi Abuelita”: What We Can Learn from First and Second Graders' Pandemic Narratives
Authors: Casesa Rhianna Henry , LaDuke Aja E. , Quiñonez Vanessa Chavez , Garibay Heidy 
Published: May 2023

AbstractThis article details a classroom‐based study designed to provide agency and voice to first and second grade emergent bilinguals as they processed the COVID‐19 pandemic. Two California teachers created a narrative writing unit not only to teach specific writing skills, but also to challenge pervasive deficit assumptions that young children “could not handle” the details or scope of this global health crisis. Students' narratives illustrated a profound awareness of the cultural, social, psychological, and academic impacts of COVID‐19. This work demonstrates that children can indeed, understand and articulate complex lived experiences, while also confirming the value of writing and drawing as powerful invitations for children to communicate and process. This project highlights the resilience of children who have been living through the COVID‐19 pandemic and what adults in their lives can learn from their reflections.
Factors influencing Scottish dairy farmers’ antibiotic use
Authors: Pate Lorna A. , Milne Catherine E. , McMorran Rob , Roberts David J. , Macrae Alastair I. 
Published: May 2023

AbstractBackgroundGood stewardship of antibiotics can reduce the development and impact of antimicrobial resistance (AMR); therefore, understanding farmers’ antibiotic use is of interest to stakeholders. To date, few qualitative studies have looked at farmers’ antibiotic use on dairy farms in the UK.MethodsSemi‐structured interviews were used to explore 15 Scottish dairy farmers’ antibiotic use behaviours and the factors influencing their antibiotic use on farms.ResultsUsing an inductive process, the results from the interviews were analysed, and four key themes were extracted: use of antibiotics, awareness of AMR, determinants of antibiotic use and future aspirations.LimitationsSome of the farmers interviewed were wary about discussing their antibiotic use, which could mean that some contentious issues were not discussed. The farmers also all belonged to a single milk‐buying group, which may limit the generalisability of the findings.ConclusionsThe quantities of antibiotics used were felt to be driven by the disease prevalence on farms, cows being indoors more, increasing herd sizes resulting in increased stocking densities, retention of poorer cows and substandard housing. Farmer knowledge of antibiotics varied, and not all farmers interviewed were aware of AMR. The farm veterinarian, the press and peers were found to be the main sources of antibiotic information.