bluuebunny/crossref_metadata_2025_split huggingface dataset:
School Nurse Perspectives on Collaboration With Primary Care Providers
Authors: Goldberg Lauren , Rankine Jacquelin , Devlin Bridgetta , Miller Elizabeth , Ray Kristin N. 
Published: March 2023

ABSTRACTBACKGROUNDSchool nurses are rarely integrated into primary care teams to their full potential. We aimed to characterize school nurses' perceptions related to current and optimal collaboration with primary care providers (PCPs) and identify actionable solutions to improve efficiency, quality, and coordination of pediatric care.METHODSWe conducted and qualitatively analyzed interviews with school nurses to characterize structures, processes, and perceived benefits of optimized school nurse‐PCP collaboration.RESULTSSchool nurse interviewees (n = 23) identified factors important to school nurse‐PCP collaboration within 2 domains: information sharing and relationship building. Information sharing themes included health information sharing laws, data sharing systems, and technology‐based communication systems. Relationship building themes included health care sector understanding of the school nurse role, PCP knowledge of school health requirements, shared professional development opportunities, and time and personnel. Perceived benefits of optimized PCP‐school nurse collaboration were identified for children, PCPs, school nurses, and parents.IMPLICATIONS FOR SCHOOL HEALTH POLICY, PRACTICE, AND EQUITYNeeds assessments and action plans guided by the domains of information sharing and relationship building can inform local improvements to optimize school nurse‐PCP collaboration.CONCLUSIONSSchool nurses highlighted cross‐sector solutions to enhance school nurse‐PCP collaboration including integrated information sharing systems and intentional relationship building.
What makes an international institution work for labor activists? Shaping international law through strategic litigation
Authors: Kahraman Filiz 
Published: March 2023

AbstractStudies on international legal mobilization often analyze the mobilization efforts of activists at a single international court. Yet we know little about how activists choose among multiple international institutions to advance social justice claims. Drawing on comparative case studies of Turkish and British trade union activists' legal mobilization efforts and case law analysis, I show that activists, guided by their lawyers, probe multiple avenues to identify the legal institution with the highest judicial authority and is most responsive to activists' claims. Once they identify their target institution, the iterative process between a responsive court and activists' strategic litigation can build a court's jurisprudence in a new issue area, even if the court provides limited de jure rights protections. Activists primarily use international litigation strategy to leverage structural reforms at the domestic level and to set new international norms through precedents.
Enlargement of opisthenar microcirculatory area predicts impaired heart function in severe acute coronary syndrome patients
Authors: Chen Chen , Zhu Bai Lin , Zheng Wei Da , Guo Zhen Yi , Jin Xin , Zhao Zai Hao , Lin Mei Hua , Cui Lan , Zhang Yin Hua 
Published: March 2023

AbstractBackgroundImpaired microcirculation in acute coronary syndrome (ACS) patients manifests inadequate recovery and adverse clinical outcome. Here, we analyzed correlations between peripheral microcirculation and heart function in ACS patients.MethodsOpisthenar microvessel area (OMA) were measured with optical coherence tomography angiography (OCTA), cardiac functional indexes (echocardiograph) were assessed 48–72 h after therapeutic interventions.ResultsResults showed that OMA normalized with heart rate (OMA‐HR) were significantly greater in ACS patients with percutaneous intervention (ACS‐PCI, n = 25, stenosis >80%) compared to those with pharmacological intervention (ACS‐PI, n = 23, stenosis <50%, p = .02). Ejection fraction (EF) and fractional shortening (FS), which were not different between two groups, showed negative correlations with OMA‐HR in ACS‐PCI (EF: r = −0.512, p = .009; FS: r = −0.594, p = .002). Cardiac output (CO) inversely correlated with OMA‐HR in both groups (r = −0.697, p < .0001; r = −0.527, p = .01). Neutrophil to lymphocyte ratio (NLR) on admission was greater in ACS‐PCI group. NLR, which was negatively associated with EF or FS, was positively associated with OMA‐HR in all patients. The area under the curve (AUC) for OMA‐HR was 0.683 (specificity 0.696 and sensitivity 0.72, p = .02). OMA‐HR at >376.5 μm2 predicts reduced FS and CO (p = .002, p = .005, respectively). Summary OMA‐HR predicts inadequate recovery of the heart in severe ACS patients post‐PCI.
A salivary secretory protein from Riptortus pedestris facilitates pest infestation and soybean staygreen syndrome
Authors: Shan Shiqi , Huang Yue , Guo Chunyun , Hu Biao , Zhang Hehong , Li Yanjun , Chen Jianping , Wei Zhongyan , Sun Zongtao 
Published: March 2023

AbstractThe bean bug (Riptortus pedestris), one of the most important pests of soybean, causes staygreen syndrome, delaying plant maturation and affecting pod development, resulting in severe crop yield loss. However, little is known about the underlying mechanism of this pest. In this study, we found that a salivary secretory protein, Rp614, induced cell death in nonhost Nicotiana benthamiana leaves. NbSGT1 and NbNDR1 are involved in Rp614‐induced cell death. Tissue specificity analysis showed that Rp614 is mainly present in salivary glands and is highly induced during pest feeding. RNA interference experiments showed that staygreen syndrome caused by R. pedestris was significantly attenuated when Rp614 was silenced. Together, our results indicate that Rp614 plays an essential role in R. pedestris infestation and provide a promising RNA interference target for pest control.
Permanent His bundle pacing in patients with right atriomegaly: The value of different dedicated delivery sheaths
Authors: Marinaccio Leonardo , Putorti Francesco , Rocchetto Eros , Giacopelli Daniele 
Published: March 2023

AbstractBackgroundAn enlarged right atrium (RA) is a challenging anatomy that can limit the successful use of His bundle pacing (HBP). It is unknown whether new implantation tools could help overcome these challenges.MethodsConsecutive patients with RA volume index >25 mL/m2 in men and >21 mL/m2 in women underwent permanent HBP. We used a stylet‐driven lead (SDL) with an extendable helix delivered via a dedicated delivery sheath (Selectra 3D, Biotronik) as a first attempt. In case of failure, a second attempt was performed with the same lead but with a different delivery curve. Finally, a lumen‐less lead (LLL) was also available as a third attempt.ResultsThe study cohort included 24 patients (median age 75.7 years [interquartile range, 70.9–79.0], 88% men) with a RA volume of 49 mL/m2 (45–54). Using SDL, HBP was achieved with a single sheath curve in 17 patients (71%). The second attempt with the same lead but a different sheath was successful in four more patients (SDL success 87%). The fluoroscopy time increased significantly when the second attempt was necessary (8 min [6–11] vs. 15 min [13–17], p < .001). In the remaining three patients, HBP was further attempted with a LLL leading to a final procedural success of 96%. No lead dislodgment nor significant increase in pacing threshold was observed at 1‐month (1.2 [0.7–1.7] V@1.0 ms vs. 1.1 [0.8–1.7] V@1.0 ms, p = .939).ConclusionThe availability of different dedicated delivery systems for HBP can improve procedural outcomes even in challenging circumstances, such as in patients with right atriomegaly.
Morphological and electrophysiological evaluation of median and ulnar nerve in complex regional pain syndrome type 1
Authors: Yüksel Emine , Inan Levent Ertuğrul , Tok Fatih 
Published: March 2023

AbstractObjectiveComplex regional pain syndrome (CRPS) can be distinguished as type I without and type II with electrophysiological evidence of major nerve lesion. The pathophysiology of both subgroups is still under investigation. The aim of this research is to demonstrate the nerve morphology and electrophysiology in CRPS type I patients.Materials and MethodsBilateral median and ulnar nerve cross‐sectional areas were evaluated with ultrasound and also median and ulnar nerve conduction studies of both hands were performed. Cross‐sectional areas of median and ulnar nerves and nerve conduction studies in healthy controls were also obtained and compared with the patients.ResultsTwenty‐five male patients and 11 healthy male controls were enrolled in the study. The mean age of the patients was 24.08 ± 5.50 years and controls was 23.18 ± 5.09 (p > 0.05). Compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) amplitudes of the diseased side were found significantly lower than the healthy side (p < 0.05). Both median and ulnar nerve distal motor latency values were significantly higher in the patient group (p < 0.05). There was no significant difference in the median and ulnar nerve cross‐sectional area when compared with the opposite extremity and healthy volunteers.ConclusionThe lower SNAP and CMAP amplitudes of the median and ulnar nerves compared to the healthy side and the prolongation of the affected side median and ulnar nerve distal motor latencies of the affected individuals may indicate axonal involvement in patients with CRPS type 1. Decreased CMAP amplitudes may also indicate muscle atrophy due to a decrease in the number of functional motor units.
Long‐term benefits of mindfulness on white matter tracts underlying the cortical midline structures in panic disorder: A 2‐year longitudinal study
Authors: Bang Minji , Kim Borah , Lee Kang Soo , Choi Tai Kiu , Lee Sang‐Hyuk 
Published: March 2023

AimsWe aimed to examine the long‐term benefits of mindfulness‐based cognitive therapy (MBCT) on white matter plasticity in the cortical midline structures (CMS) for a period of 2 years in patients with panic disorder and the relationships between white matter changes in the CMS and severity of state and trait symptoms.MethodsSeventy‐one participants were enrolled and underwent diffusion tensor imaging at baseline and after 2 years (26 who received MBCT as an adjunct to pharmacotherapy [MBCT+PT], 20 treated with pharmacotherapy alone [PT‐alone], and 25 healthy controls [HCs]). The severity of symptoms and fractional anisotropy (FA) in white matter regions underlying the CMS were assessed at baseline and 2‐year follow‐up.ResultsThe MBCT+PT group showed better outcomes after 2 years than the PT‐alone group. The groups showed different FA changes: the MBCT+PT group showed decreased FA in the left anterior cingulate cortex (ACC); the PT‐alone group showed increased FA in the bilateral dorsomedial prefrontal cortex, posterior cingulate cortex (PCC), and precuneus. Decreased white matter FA in the ACC, PCC, and precuneus was associated with improvements in the severity of state and trait symptoms in patients with panic disorder.ConclusionAlleviation of excessive white matter connectivity in the CMS after MBCT leads to improvements in clinical symptoms and trait vulnerability in patients with panic disorder. Our study provides new evidence for the long‐term benefits of MBCT on white matter plasticity and its clinical applicability as a robust treatment for panic disorder.
Successful sequential liver and hematopoietic stem cell transplantation in a patient with Fanconi anemia
Authors: Di Stasio Fabiana , Bravi Michela , Bonanomi Sonia , Balduzzi Adriana , Prunotto Giulia , Migliorino Guglielmo Marco , Dufour Carlo , D'Antiga Lorenzo , Vendemini Francesca 
Published: March 2023

AbstractBackgroundIn Fanconi anemia bone marrow failure is the major cause of morbidity and mortality and hematopoietic stem cell transplantation represents the only curative treatment. Liver disease, in terms of elevated liver function tests, as well as benign and malignant liver tumors, occurs especially in case of androgen treatment. We report a unique case of a child with Fanconi anemia with FANCD2 mutation who developed neonatal cryptogenic liver cirrhosis and bone marrow failure. The child successfully underwent sequential liver transplantation and hematopoietic stem cell transplantation in the first 2 years of life. Nineteen months after hematopoietic stem cell transplantation and 30 months after liver transplantation, the patient is clinically well with normal hematopoietic function and excellent liver function.ConclusionThis is the first FA patient who successfully received sequential LT and HSCT highlighting that successful sequential transplantation is feasible in Fanconi anemia patients.
Photosensitizer‐Mesoporous Silica Nanoparticles Combination for Enhanced Photodynamic Therapy†
Authors: Prieto‐Montero Ruth , Arbeloa Teresa , Martínez‐Martínez Virginia 
Published: March 2023

AbstractMesoporous silica nanoparticles (MSNs) are widely known for their versatile applications. One of the most extended is as drug delivery systems for the treatment of cancer and other diseases. This review compiles the most representative examples in the last years of functionalized MSNs as photosensitizer carriers for photodynamic therapy (PDT) against cancer. Several commercially available photosensitizers (PSs) demonstrated poor solubility in an aqueous medium and insufficient selectivity for cancer tissues. The tumor specificity of PSs is a key factor for enhancing the PDT effect and at the same time reducing side effects. The use of nanoparticles and particularly MSNs, in which PS is covalently anchored or physically embedded, can overcome these limitations. For that, PS‐MSNs can be externally decorated with compounds of interest in order to act as an active target for certain cancer cells, demonstrating enhanced phototoxicity in vitro and in vivo. The objective of this review is to collect and compare different nanosystems based on PS‐MSNs pointing out their advantages in PDT against diverse types of cancers.
Contract selection and piracy surveillance for video platforms in the age of social media
Authors: Jiang Zhong‐Zhong , Cui Shiliang , He Na , Li Kunyang , Tian Lin 
Published: March 2023

AbstractPirated video clips, a new form of piracy, have spread rapidly in recent years with the vigorous development of short‐video social media platforms such as TikTok and Douyin. This has led to a huge loss of revenue for the film and TV drama industry where the negative economic impact trickles down from legitimate video platforms to content creators. As video platforms fight back against copyright infringement, they need to decide how much effort to invest in detecting and taking down pirated video clips that emerge on social media platforms. In addition, they need to decide whether a lump sum or unit price contract should be used to secure the playing rights for a video from the content creator. A content creator has no incentive to engage in piracy surveillance together with the video platform after signing a lump sum contract but has an incentive to do so after signing a unit price contract because he/she would receive royalties each time someone watches the copyrighted video. Using an analytical model framework, we find that the video platform should use a unit price contract when production of the video is less costly for the same quality (e.g., music‐based, horror, and romance movies) but a lump sum contract when production is costly (e.g., Sci‐fi, animation, and fantasy genres). We show that in equilibrium, the total surveillance effort between the video platform and the content creator is smaller and the video platform charges customers less to watch the copyrighted video under the lump sum contract compared to the unit price contract. As a result, the lump sum contract not only achieves higher consumer surplus compared to the unit price contract but also leads to a higher percentage of customers legally accessing the video program. Finally, the content creator's revenue is the same under both contracts, but the content creator may prefer the lump sum contract because it attracts more (legal or illegal) viewers and the increased visibility could be beneficial in the long run.
Acetic acid enhances drought tolerance more in female than in male willows
Authors: Xia Linchao , Yao Yuan , Zeng Yi , Guo Zian , Zhang Sheng 
Published: March 2023

AbstractDrought is an important stress factor that limits plant growth and development. Female willows generally display stronger drought tolerance than males. The application of exogenous acetic acid (AA) has emerged as an efficient and eco‐friendly approach to facilitate drought tolerance in willows. However, whether AA exerts sexually different effects on willows remains undefined. In this study, we comprehensively performed morphological and physiological analyses on three willow species, Salix rehderiana, Salix babylonica, and Salix matsudana, to investigate the sexually different responses to drought and AA. The results indicated that willow females were more drought‐tolerant than males. AA application effectively enhanced willows' drought tolerance, and females applied with AA displayed greater root distribution and activity, stronger osmotic and antioxidant capacity and photosynthetic rate but less reactive oxygen species, or abscisic acid‐mediated stomatal closure than males. In addition, AA application enhanced the jasmonic acid signaling pathway in females but inhibited it in males, conferring stronger drought defense capacity in female willows than in males. Overall, AA application improves drought tolerance more in female than in male willows, further enlarging the sexual differences in willows under drought‐stressed conditions.
Effects of frequency of the stale seedbed after autumn or spring ploughing on weed density and composition in sown lemon balm
Authors: Junker Charlotte , Neuhoff Daniel , Döring Thomas 
Published: March 2023

AbstractWeed management in organic farming needs to integrate a wide range of preventive tools. Here we tested the stale seed bed technique in field experiments with organic lemon balm. In a two‐factorial trial, four intensities of stale seedbed after either autumn or spring ploughing were tested in 2019/2020 and 2020/2021 on alluvial loams of the research farm Wiesengut in the Rhineland, Germany. Increasing the number of stale seedbed passes did not promote weed emergence before sowing in 2020 due to serious spring drought; in 2021 only the two last stale seedbed passes in later spring caused extra weed flushes, while cold weather conditions in early spring prevented weed response to the earlier passes. Despite the differences in the number of germinating weeds in 2021 before sowing, intensification of the stale seedbed had no decreasing effect on weed density in lemon balm after sowing. However, weed species‐specific periods were identified in which the stale seedbed selectively promoted emergence. Autumn ploughing followed by a superficial incorporation of the catch crop in spring resulted in a lower weed emergence than complete residue incorporation by spring ploughing. Seedbank size differed greatly between fields, probably due to crop rotation. The overall weed reducing effect of the tested tillage treatments was low, probably due to high weed pressure on the organic farm. To increase the efficacy of the stale seed bed technique, sufficient soil moisture as well as temperature requirements of the dominating weed flora need to be considered.
Metabolic and ruck performance effects of a novel, light‐weight, energy‐dense ketogenic bar
Authors: Buga Alex , Crabtree Chris D. , Stoner Justen T. , Decker Drew D. , Robinson Bradley T. , Kackley Madison L. , Sapper Teryn N. , Buxton Jeffrey D. , D'Agostino Dominic P. , McClure Tyler S. , Berardi Anthony , Cline Shawn , Fleck Trevor , Krout Jared , Newby Doran , Koutnik Andrew P. , Volek Jeff S. , Prins Philip J. 
Published: March 2023

AbstractRucksack marches (‘rucks’) are strenuous, military‐relevant exercises that may benefit from pre‐event fuelling. The purpose of this investigation was to explore whether acute ingestion of carbohydrate‐ or lipid‐based nutritional bars before rucking can elicit unique advantages that augment exercise performance. Recreationally active and healthy males (n = 29) were randomized and counterbalanced to consume 1000 kcal derived from a novel, energy‐dense (percentage energy from carbohydrate/fat/protein: 5/83/12) ketogenic bar (KB), or isocaloric high‐carbohydrate bars (CB; 61/23/16) 3 h before a time‐to‐exhaustion (TTE) ruck. Conditions were separated by a 1‐week washout. The rucksack weight was standardized to 30% of bodyweight. Steady‐state treadmill pace was set at 3.2 km/h (0.89 m/s) and 14% grade. TTE was the primary outcome; respiratory exchange ratio (RER), capillary ketones (R‐β‐hydroxybutyrate), glucose and lactate, plus subjective thirst/hunger were the secondary outcomes. Mean TTE was similar between conditions (KB: 55 ± 25 vs. CB: 54 ± 22 min; P = 0.687). The RER and substrate oxidation rates revealed greater fat and carbohydrate oxidation after the KB and CB, respectively (all P < 0.0001). Capillary R‐βHB increased modestly after the KB ingestion (P < 0.0001). Neither bar influenced glycaemia. Lactate increased during the ruck independent of the condition (P < 0.0001). Thirst/fullness perceptions changed independent of the nutritional bar consumed. A novel KB nutritional bar produced equivalent TTE ruck results to the isocaloric CBs. The KB's energy density relative to CB (6.6 vs. 3.8 kcal/g) may provide a lightweight (–42% weight), pre‐event fuelling alternative that does not compromise ruck physical performance.
Cavitation Modeling Using Lumped Parameter Approach Accounting for Bubble Dynamics and Mass Transport Through the Bubble Interface
Authors: Mistry Zubin , Vacca Andrea 
Published: March 2023

AbstractVaporous and gaseous cavitation cause several physical phenomena which are typically undesirable, such as reduction in compressibility and material damage. Therefore, the ability to capture these effects in simulation is highly valued. In the fluid power field, lumped parameter modeling technique has proven effective for analyzing components and systems, allowing for fast simulations. Past efforts in modeling cavitation using lumped parameter approach have assumed dependence of fluid properties such as bulk modulus, density, and viscosity directly to pressure and temperature. This cannot be considered as the fluid mixture is composed of different phases of matter. Some other formulations account for gaseous cavitation based on the equations that are derived from vaporous cavitation. This paper illustrates a better approach that combines the two cavitation effects by considering that both vapor and undissolved gas co-occupy a spherical bubble. The size of the spherical bubble is solved using the Rayleigh–Plesset equation, and the transfer of gas through the bubble interface is solved using Henry's law and diffusion of the dissolved gas in the liquid. These equations are coupled with a novel pressure derivative equation. To show the validity of the proposed approach, the instantaneous pressure of a closed fluid volume undergoing expansion/compression is compared with multiple experimental sources, showing an improvement in accuracy when compared to existing models. Integrating this modeling technique with current displacement chamber simulation can further improve the understanding of cavitation in hydraulic systems.