bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compound Equilibrium in a Polarized Polity — Lessons from American Democracy
Authors: Szklarski Bohdan 
Published: January 2025

Abstract
In the study of political systems, equilibrium stands as a cornerstone, underpinning stability and legitimacy. As we navigate the third decade of the 21st century, amid growing threats to democratic validity, it becomes crucial to re-examine this equilibrium principle. Even established democracies like the USA aren’t immune to the pitfalls of polarization, tribalization, and radicalization. In this text, we aim to explore the resilience of equilibrium in the face of these destabilizing trends. Equilibrium, traditionally viewed as a cohesive product of political competition coming as if naturally, is a mark of consolidated democracy. Yet today, as even robust democracies face internal crises, strained by polarization and fragmentation, the concept of equilibrium evolves to become a compound equilibrium consisting of disjointed axes of conflict, each seeking its individual balance. Such systems necessitate greater leadership intervention or require new rules and processes to restore cohesion. In this text we pose numerous questions about the way this process of fragmentation is overcome and compound equilibrium achieved. Interestingly, some of the measures call on limiting rather than enhancing democracy. The analysis has its historical context. Post-Cold War America exemplifies the notion that more democracy doesn’t necessarily equate to stronger democracy. While the focus here is primarily on the American system, as more democratic nations adopt its practices (such as debates and primaries), it’s hoped that insights from the USA can shed light on how democracies globally might respond to internal and external challenges to their equilibrium.
POSSIBLE PHARMACOLOGICAL BASIS FOR ANTITHROMBOTIC EFFECT OF GLYCYRRHIZA GLABRA IN SPRAGUE DAWLEY RATS
Authors: Jain M. , Yadav A. , Tomar V. , Kannojia P. , Solanki S. S. , Tonpay S. D. 
Published: January 2025

It has been previously identified that 3-aryl comarin derivative, GU-7 isolated from Liquorice posses Antiplatelet activity. It inhibits platelet aggregation by increasing intraplatelet cyclic AMP concentration. Here we report the in-vivo effects of extract of Glycyrrhiza glabra and also the combined effect with Vitamin K and Heparin. Extract of Glycyrrhiza glabraincreased the bleeding time when given in the doses of 180 mg/kg and 360 mg/kg. Blood loss was evaluated 60 minute later as a function of absorbance at 540 nm due to hemoglobin content in water solution. Altogether data indicates that Glycyrrhiza glabra is an effective anti thrombotic agent in vivo, which may account for its known pharmacological properties.
ANALGESIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF PAVETTA INDICA
Authors: Golwala D. K. , Patel L. D. , Bothara S. B. , Patel P. M. , Vaidya S. K. , Raval M. K. 
Published: January 2025

The present study was designed to investigate Analgesic activity of ethanolic leaf extract of Pavetta indica, using hot plate method and tail clip method. Ethanolic extract was administered intraperitoneally at doses of 60 mg/kg and 80 mg/kg to Swiss albino mice and Wister rats. Ethanolic leaf extract of Pavetta indica showed significant (p<0.01) inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.
BENZOTHIAZOLE: DIFFERENT METHODS OF SYNTHESIS AND DIVERSE BIOLOGICAL ACTIVITIES
Authors: Yadav P S , Prakash Dev , Senthilkumar G P 
Published: January 2025

Substituted 1, 3-benzothiazole derivatives are an important class of heterocyclic compounds. In recent years heterocyclic compounds analogues and derivatives have attracted strong interest due to their biological and pharmacological properties. The benzothiazole nucleus containing compounds involved in research aimed at evaluating new products that possess biological activities, such as antimicrobial, anticancer, antifungal, anthelmintic, anti-diabetic, amyloid imagining agents and anticancer agents. The present review focus on the different methods of synthesis of substituted benzothiazoles with potential activities that are now in developing phase.
<i>Citrullus lanatus</i> (Thunb) improves an antidepressant-induced impaired fertility in depressed male mouse model
Authors: Kumar Sandeep , Tripathi Anima , Singh Poonam 
Published: January 2025

Synthetic antidepressants are used in the treatment of mental illness, however due to their side effects people are orienting towards the herbal product as an alternative therapy. The present study therefore, explores the role of C. lanatus (CL) seed extract in evaluating the fluoxetine-induced impaired sperm functions, and fertility of the depressed mice. Adult Swiss strain male mice were separated into six group. Every group contains six animals. Group I received vehicle-treated negative control while Groups II, III, IV, V and VI administered with reserpine (RES) at dose of 0.75 mg/kgBW/day, for 14 days to induce depression, fluoxetine (FLX) at the dose of 40 mg/kgBW/day in depressed mice (positive control) for 28 days, CL seed extract (300 mg/kgBW/day) only, in normal mice, and co-administrations of FLX (40 mg/kgBW/day) with low and high doses of seed extract of CL (150 mg/kgBW/day and 300 mg/kgBW/day) respectively, in the depressed mice for the same duration. Mice of Gr. II and Gr. IV did not alter the epididymal sperm parameters and fertility. However, significant alterations were observed in such parameters in the mice of Gr. III. Partial to complete restorations were noticed in such parameters in Gr. V and VI, as compared to the positive control of Gr. III. The findings suggest that CL seed extract may emerge as a potential herbal remedy to impaired fertility which could be of therapeutic drug in future.
Abundancia y composición de residuos marinos en playas de la bahía de Buenaventura, en el Pacífico Colombiano
Authors: Molina Sandoval Andrés Esteban , Sánchez-Giraldo Nathalia , Duque Guillermo 
Published: January 2025

La contaminación por residuos marinos (RM) ha ido en aumento afectando los ecosistemas costeros. Este estudio tuvo como objetivo analizar la influencia de la variabilidad ambiental espacial y estacional sobre la densidad, masa y composición de los residuos marinos y evaluar el estado de contaminación en playas de la bahía de Buenaventura, Pacifico colombiano. Las muestras se colectaron en la zona intermareal en las playas Comba, La Bocana y Piangüita, en las épocas secas, de transición y lluviosa, usando cuadrantes ubicados aleatoriamente en los transectos establecidos. Los RM fueron clasificados con base en los materiales más comunes y en el caso de los plásticos estos a su vez se agruparon por polímero. Siendo el de mayor predominancia el poliestireno expandido. La densidad promedio de 17.46 ± 25.5 ítems m-2, siendo los artículos de plástico los más comunes (96.6%). Se encontraron diferencias significativas espaciales y temporales, siendo la playa La Bocana en la época seca las de mayor contaminación (78.84±31.2 ítems m-2). Se presentaron correlaciones entre la precipitación y la salinidad con el total de residuos y dos tipos de polímeros. La aplicación de los índices de costa limpia e índice de abundancia de plástico clasifico a las tres playas en un estado de limpieza inaceptable. Por lo tanto, estas playas estudiadas pueden ser vulnerables al aumento de los RM por el crecimiento poblacional, el manejo inadecuado de los residuos y la carencia de educación ambiental.
Analisis Kebutuhan Tenaga Rekam Medis Menggunakan Metode Workload Indicator Staff Needs (WISN) Di Unit Rekam Medis Puskesmas Langsat Pekanbaru
Authors: Natassa Jihan , Maimun Nur , Ulfa Henny Maria , Wardani Sri , Isnani Rama 
Published: January 2025

Sumber Daya Manusia merupakan salah satu komponen penting sebuah institusi yang berperan sebagai, pemikir, dan perencana perkembangan suatu Lembaga. Setiap institusi perlu menganalisis dan mengidentifikasi ketersediaan SDM agar dapat mencapai tujuannya. Salah satunya dengan memetakan beban kerjanya. Kunjungan pasien pada puskesmas langsat berjumlah 35-40 orang/hari. Petugas rekam medis sebanyak 2 orang dan tidak ada yang berpendidikan D3 Rekam Medis. Tujuan penelitian ini untuk mengetahui perkiraan jumlah tenaga rekam medis menggunakan metode WISN. Penelitian ini menggunakan desain penelitian deskriptif kualitatif dengan metode time and motion study . Informan penelitian adalah petugas rekam medis sebanyak 2 orang dan 1 orang kepala TU. Pengumpulan data menggunakan instrumen tabel observasi, wawancara, stopwatch dan komputer lalu dianalisis menggunakan metode WISN. Waktu penelitian dilaksanakan pada bulan Agustus 2023. Variabel penelitian ini adalah waktu kerja tersedia, standar beban kerja, standar kelonggaran, jumlah kebutuhan tenaga kerja. Hasil penelitian adalah waktu kerja tersedia berjumlah 69.360 menit/tahun, standar beban kerja berjumlah 180.336 menit/tahun, standar kelonggaran berjumlah 15.480 menit/tahun atau 0,22, kebutuhan tenaga kerja berjumlah 3 orang. Dari hasil perhitungan tenaga kerja diharapkan adanya penambahan petugas sebanyak 1 orang khususnya tenaga D3 Rekam Medis.
Faktor yang Meningkatkan Kepatuhan Perawat dalam Penerapan Ventilator Bundle : Kajian Literatur
Authors: Erdiana Rhamalia  , Inge Dhamanti  
Published: January 2025

Latar Belakang: Ventilator Associated Pneumonia (VAP) adalah infeksi pneumonia setelah 48 jam pemakaian ventilasi mekanik. Menurut WHO tahun 2018, insiden VAP pasien ventilasi mekanik sekitar 22,8% di dunia dan menyumbang 86% dari infeksi nosokomial dengan insiden VAP global meningkat antara 9-27%. Meskipun terstandarisasi, angka kepatuhan perawat terhadap ventilator bundle rendah. Tujuan: mengetahui faktor yang meningkatkan kepatuhan perawat dalam menerapkan ventilator bundle. Metode: Penelitian dilakukan pada Juni-September 2024. Penelitian menggunakan kajian literatur yang berada pada rentang tahun 2020-2024. Pencarian menggunakan database PubMed dan Google Scholar dengan alur pencarian PRISMA. Hasil: peningkatan kepatuhan perawat dalam penerapan ventilator bundle memiliki rata-rata sebesar 22,56%. Beberapa lokasi penelitian yang dikaji terdapat di berbagai rumah sakit dunia, seperti Brazil, Hungaria, Argentina, dan India. Desain penelitian atau rancang bangun yang dominan pada kajian adalah berupa cross sectional. Dalam kajian diketahui bahwa pengetahuan perawat dan pendidikan yang berbasis kombinasi dari metode gamifikasi, debriefing, dan simulasi terkait ventilator bundle sebagai faktor internal. Selain itu, monitoring checklist ventilator bundle sebagai karakteristik lingkungan pada faktor eksternal. Simpulan: faktor internal yang peningkat kepatuhan perawat adalah pengetahuan dan pendidikan ventilator bundle, sedangkan faktor eksternal adalah karakteristik lingkungan berupa checklist ventilator bundle, sehingga perlu diterapkan untuk mencapai kepatuhan sesuai standar.
DIAMOND-BLACKFEN ANEMIA WITH SEVERE POSTTRANSFUSION IRON OVERLOAD
Authors: Argunova E. F. , Kharabaeva E. M. , Protopopova N. N. , Kondratieva S. A. , Yadreeva O. V. , Nikolaeva S. A. 
Published: January 2025

Diamond-Blackfan anemia (DBA) is a rare form of congenital red cell aplasia of hematopoiesis in infants and children, characterized by suppression of erythropoiesis and congenital malformations. The article presents an observation of a child with DBA. The girl was born with severe anemia. The diagnosis was established at the age of 3 months, genetically conﬁrmed at 2 years. Since her birth, she had been receiving monthly transfusion therapy with red blood cells. Treatment with prednisolone, L-leucine was carried out without effect, the child remained transfusion-dependent. The only curative method for this disease is hematopoietic stem cell transplantation (HSCT). With a 14-year-old sibling not suitable, there was no other suitable related donor. By the age of 15, the child had developed serious complications caused by post-transfusion iron overload of the liver (grade 4), myocardium, pituitary gland with the development of liver and heart failure; endocrine disorders in the form of hypopituitarism, primary and secondary hypothyroidism, increased fasting glycemia. In addition, the girl has chronic viral hepatitis C. In order to remove excess iron from the body, the patient has been receiving chelation therapy since the age of 8.The accumulation of iron in organs leads to irreversible dysfunction, reducing the life expectancy of patients with DBA, so early initiation of chelation therapy is necessary.
SCIENTIFIC SCHOOL OF ACADEMICIAN PALMIRA PETROVA
Authors: Borisova N. V. 
Published: January 2025

Being the core of the scientiﬁc community, scientiﬁc schools play a special role in the formation of civil society. In addition to purely subject content, a scientiﬁc school is essentially an effective model of education as a transmitter of cultural norms and values of the scientiﬁc community from the older to the younger generation.The scientiﬁc school “Physiological and Medical Aspects of Health of Various Population Groups in the Sakha Republic (Yakutia)” is an example of organizing interdisciplinary research devoted to the problem of human health in the extreme conditions of the North and its interaction with the ecology of the environment. The article is dedicated to the founder of the scientiﬁc school, Academician of the Academy of Sciences of the Sakha Republic (Yakutia), Doctor of Medical Sciences, Professor Palmira Georgievna Petrova.
ПРОГНОЗ ОБРАЗОВАНИЯ ПРОВАЛОВ НА ПОДРАБОТАННЫХ ТЕРРИТОРИЯХ МЕТОДОМ ИСКУССТВЕННОГО ИНТЕЛЛЕКТА НА ОСНОВЕ НЕЙРОННЫХ СЕТЕЙ
Authors: Дрибан В.А. , Хохлов Б.В. , Антипенко А.В. 
Published: January 2025

В статье приведены результаты анализа геомеханической обстановки в пределах горного отвода шахты им. В. М. Бажанова. В настоящее время массовое закрытие угольных шахт с их последующим затоплением привело к кардинальному перераспределению гидродинамического режима подземных вод. Это стало причиной активизации геомеханических процессов, в том числе процессов самоликвидации сохранившихся горных выработок и пустот в горном массиве, вплоть до образования провалов земной поверхности. Как следствие, нарушаются эксплуатационные способности (в некоторых случаях вплоть до разрушения) зданий, сооружений и других объектов, расположенных на земной поверхности, что существенным образом увеличивает риски при ведении хозяйственной деятельности, а также создает угрозу жизни и здоровью людей. Поэтому для поля шахты им. В. М. Бажанова был выполнен прогноз вероятности образования провалов земной поверхности по двум методикам: нормативной и с применением искусственного интеллекта. Представленная нейронная сеть разработана в отделе горного давления ФГБНУ «РАНИМИ» на основе нормативной методики, с учетом требований нормативных документов и проведенных исследований.
The article presents the results of an analysis of the geomechanical situation within the mining allotment of the mine named after V. M. Bazhanov. Currently, the mass closure of coal mines with subsequent flooding has led to a radical redistribution of the hydrodynamic regime of underground waters. This has led to the activation of geomechanical processes, including the self-liquidation processes of remaining mine workings and voids in the rock mass, up to the formation of ground surface collapses. As a result, the operational capabilities (in some cases, up to destruction) of buildings, structures, and other objects located on the ground surface are disrupted, significantly increasing the risks associated with economic activities and posing a threat to the lives and health of people. Therefore, a forecast of the probability of ground surface collapses was carried out for the mine named after V. M. Bazhanov, using two methods: normative and with the application of artificial intelligence. The neural network presented was developed by the Mining Pressure Department of the Federal State Budgetary Institution RANIMI based on the normative methodology, considering the requirements of regulatory documents and conducted research.
ВЛИЯНИЕ ВЛАГОСОДЕРЖАНИЯ НА КАЧЕСТВЕННЫЕ ПОКАЗАТЕЛИ ЭКСТРУДАТОВ В ТЕХНОЛОГИИ ПЕРЕРАБОТКИ СМЕСИ РИСОВОЙ КРУПЫ С ПРОДУКТАМИ БИОКОНВЕРСИИ ТОПИНАМБУРА
Authors: Шариков Антон Юрьевич , Амелякина Мария Валентиновна , Иванов Виктор Витальевич , Туршатов Михаил Владимирович , Соловьев Александр Олегович , Абрамова Ирина Михайловна 
Published: January 2025

Перспективность переработки топинамбура на спирт и его использования в других технологиях биоконверсии показана многими исследованиями, при этом актуальной задачей является утилизация образуемых вторичных сырьевых ресурсов. Целью данного исследования стало изучение влияния влагосодержания смесей рисовой крупы и 6% высушенной дисперсной фракции топинамбура, образуемой в процессе его переработки на спирт, на режимы экструзии, технологические показатели экструдатов, рассматриваемых как основа для продуктов быстрого приготовления. Полученные экструдаты оценивали по следующим качественным характеристикам: коэффициент расширения, насыпная плотность, твердость, количество микроразломов, цветовые характеристики в системе CIE Lab, растворимость, набухаемость. Проведенные исследования показали, что со снижением влажности с 20% до 12,5% происходило ужесточение режима экструзии, повышались температура со 155 до 170°С, давление с 2,0 до 4,0 МПа, момент сдвиговых деформаций с 48 до 80%, удельная механическая энергия на 67% с 0,109 до 0,182 кВт·час/кг. Уровень влагосодержания экструдируемых смесей прямо коррелировал с насыпной плотностью экструдатов и их твердостью, которые увеличивались с 73,5 до 227,2 г/дм3 и с 4,4 до 41,7 Н, соответственно, с ростом влагосодержания с 12,5 до 20%. Для других показателей отмечена обратная корреляция, количество микроразломов снижается с 11,8 до 4,7, коэффициент расширения с 13,7 до 4,1, показатель набухаемости с 10,4 до 7,2 см3/г и растворимости с 80 до 49 %. Динамическая вязкость суспензий экструдатов, имитирующих приготовление быстрорастворимых каш в бытовых условиях, снижалась с 3,3 до 2,0 Па·с со снижением влагосодержания. Установлено, что внесение дисперсной фракции топинамбура повышает пористость продукта, оказывает изменения на цветовые характеристики образцов, Исследованиями показана перспективность использования дисперсной фракции топинамбура в экструзионной технологии продуктов быстрого приготовления с целью повышения содержания пищевых волокон.
РАСПОЗНАВАНИЕ ОПАСНЫХ ОБЪЕКТОВ КОСМИЧЕСКИМ АППАРАТОМ МОНИТОРИНГА ОКОЛОЗЕМНОГО КОСМИЧЕСКОГО ПРОСТРАНСТВА
Authors: СЛАТОВА Е В. , АРСЕНЬЕВ В Н. 
Published: January 2025

Рассматривается задача определения наиболее опасных элементов космического мусора в околоземном космическом пространстве специализированным космическим аппаратом, оснащенным бортовой аппаратурой наблюдения: оптико-электронным и радиолокационным средствами с различными вероятностями принятия ошибочныгхрешений. В процессе применения бортовой аппаратуры наблюдения по назначению накапливается опытная информация о характеристиках входящих в нее средств. Для повышения вероятности принятия правильного решения о наиболее опасном объекте предлагается использовать параллельно с расчетными характеристиками оптико-электронных и радиолокационных средств результаты их реального применения. Приведен пример.
The problem of identifying the most dangerous elements of space debris in near-Earth space using a specialized spacecraft equipped with on-board observation equipment: optical-electronic and radar equipment with different probabilities of making erroneous decisions is considered. In the process of using on-board surveillance equipment for its intended purpose, experimental information about the characteristics of its components is accumulated. To increase the likelihood of making the right decision about the most dangerous object, it is proposed to use the results of their actual use in parallel with the calculated characteristics of optical-electronic and radar equipment. An example is given.
Studying the Knowledge, Attitude, and Practice of HealthCare Workers Towards Hepatitis B Virus Prevention in Hospitals, Hodeidah City, Yemen, 2024
Authors: Taha Mogeeb Saeed , Al-Wesabi Sadeq Abdo Mohammed , Al-Selwi Khaled , Suhail Mohammed Ahmed , Al-Nahary Radman Ahmed , Baalwi Abdulaziz Ahmed , Ghanim Nabil Ahmed Saif 
Published: January 2025

Background: Hepatitis B virus (HBV) infection is a public health problem. Healthcare workers (HCWs) are at a high risk for blood-borne pathogens due to their contact with patients and contaminated instruments. Vaccination of HCWs against HBV is standard practice in many countries but is often not implemented in resource-poor settings. to determine HBV knowledge attitude and practice, a study conducted in Al-Mukalla City a majority of participants had poor knowledge and practice about hepatitis B and its management. Also, the vast majority had a negative attitude toward hepatitis B virus . Objective: The purpose of this study was to evaluate the knowledge, attitude, and practice (KAP) of HCWs towards hepatitis B infection in Hospitals, Hodeidah city. Methodology: We enrolled 290 HCWs from the main public and privet hospitals (Athwrah and Alamal Hospitals). Their demographics, medical histories, HBV vaccination details and risk factors for contracting blood-borne infections were collected using a standardized questionnaire. The study was conducted during the period of 1st of March to 1st of May 2024 . Results: The overall KAP scores of HCWs were found to be 20%, 99.7%, and 30%,were positive respectively. Most of the participants correctly recognized the HBV infection. Among the participants, only 15% had undergone screening for HBV, and 43.8% had received HBV vaccine. Moreover, only 43% had completed the three doses of vaccination for HBV. Among the HCWs, the group with higher education level had better knowledge than the group with lower education level. However, the attitude of most of the participants towards HBV prevention was found to be adequate . (99.7%). Conclusion: This study shows that HCWs in Hodeidah, Yemen is at high risk of HBV infection due to low vaccination coverage and inadequate infection control. Therefore, we strongly encourage providing an accessible and compulsory vaccination program for all HCWs to improve their attitude and awareness towards HBV infection and to achieve effective infection control.