bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum anti-erythropoietin antibodies among pregnant women with Plasmodium falciparum malaria and anaemia: A case-control study in northern Ghana
Authors: Nkansah Charles , Bannison Bani Simon , Mensah Kofi , Appiah Samuel Kwasi , Osei-Boakye Felix , Abbam Gabriel , Daud Samira , Agyare Eugene Mensah , Agbadza Peace Esenam , Derigubah Charles Angnataa , Serwaa Dorcas , Apodola Francis Atoroba , Quansah Yeduah , Issah Rahama , Dindiok Samuel Yennuloom , Chukwurah Felix Ejike 
Published: March 2023

Background
Anaemia in pregnancy is common in underdeveloped countries, and malaria remains the predominant cause of the condition in Ghana. Anti-erythropoietin (anti-EPO) antibody production may be implicated in the pathogenesis of Plasmodium falciparum malaria-related anaemia in pregnancy. This study ascertained the prevalence of anti-EPO antibody production and evaluated the antibodies’ relationship with Plasmodium falciparum malaria and malaria-related anaemia in pregnancy.

Methods
This hospital-based case-control study recruited a total of 85 pregnant women (55 with Plasmodium falciparum malaria and 30 controls without malaria). Venous blood was taken from participants for thick and thin blood films for malaria parasite microscopy. Complete blood count (CBC) analyses were done using an automated haematology analyzer. Sandwich enzyme-linked immunosorbent assay (ELISA) was used to assess serum erythropoietin (EPO) levels and anti-EPO antibodies. Data were analyzed using IBM SPSS version 22.0.

Results
Haemoglobin (p<0.001), RBC (p<0.001), HCT (p = 0.006) and platelet (p<0.001) were significantly lower among pregnant women infected with Plasmodium falciparum. Of the 85 participants, five (5.9%) had anti-EPO antibodies in their sera, and the prevalence of anti-EPO antibody production among the Plasmodium falciparum-infected pregnant women was 9.1%. Plasmodium falciparum-infected pregnant women with anti-EPO antibodies had lower Hb (p<0.001), RBC (p<0.001), and HCT (p<0.001), but higher EPO levels (p<0.001). Younger age (p = 0.013) and high parasite density (p = 0.004) were significantly associated with Plasmodium falciparum-related anti-EPO antibodies production in pregnancy. Also, younger age (p = 0.039) and anti-EPO antibody production (p = 0.012) related to the development of Plasmodium falciparum malaria anaemia in pregnancy.

Conclusion
The prevalence of anti-EPO antibodies among pregnant women with Plasmodium falciparum malaria was high. Plasmodium falciparum parasite density and younger age could stimulate the production of anti-EPO antibodies, and the antibodies may contribute to the development of malarial anaemia in pregnancy. Screening for anti-EPO antibodies should be considered in pregnant women with P. falciparum malaria.
Between ‘minjung’ and ‘literature’: Korean labor poetry and reportage literature in the 1980s
Authors: Kim Nahyun 
Published: March 2023

This paper reviews three books which symbolically represent a new direction in ‘minjung literature’ in the 1980s. Labor poet Park No-hae (박노해)’s collection of poems, Dawn of Labor (노동의 새벽), was popular when it was published because it was literature in the form of poetry written by a real member of the minjung who kept his identity as a worker secret by becoming a faceless poet. Song Hyo-soon (송효순)’s memoir, Road to Seoul (서울로 가는 길) records the miserable reality of factories as the subaltern writing. Park Tae-soon (박태순)’s The Land and the Minjung (국토와 민중) was reportage (reporting) literature that records his travels around the country. He shows that the history of ‘minjung’ physically exists within the country and testifies that the land was owned by the ‘minjung’. These three books reflect how ‘minjung literature’ in the 1980s testified to the ‘minjung’. Concern about how to describe and represent the ‘minjung’ shows thoughts about both the ‘minjung’ and literature. The ‘minjung’ testimonies written in a variety of literary styles cause readers to ask themselves what literature is. ‘Minjung’ poetry poetry and reportage in the 1980s can help answer this question.
Optical differential phase shift keying transceiver systems performance efficiency at high data rate optical systems in the presence of Pr doped amplifiers
Authors: Rashed Ahmed Nabih Zaki , Krishnan Kannan , Prabu Ramachandran Thandaiah , Xavier Benisha Maria , Ahammad Shaik Hasane , Hossain Md. Amzad 
Published: March 2023

Abstract
This work has been clarified the optical differential phase shift keying transceiver systems performance efficiency at high data rate optical systems in the presence of pr doped amplifiers. The Max optical signal power variations after fiber link versus wavelength variations at various system data rates are demonstrated. The total optical power within optical fiber at data rates from 10 to 100 Gbps are indicated. The Max electrical signal power variations against frequency after receiver variations at various system data rates are clarified. The total electrical power after receiver at various system data rates are demonstrated. The light/electrical power received, OSNR and SNR variations in relation to data rate variations are also studied.
An Empirical Study of Regulatory Capture in Kenya’s Maize Seed Sector
Authors: Van Dycke Lodewijk Guido K. , Mawia Harriet , Rutsaert Pieter , Donovan Jason 
Published: March 2023

Abstract
In sub-Saharan Africa, public sector breeding programs depend on local seed companies to deliver new maize varieties to farmers. Such varieties are needed to adapt cropping systems to climate change. While dozens of small and medium seed companies have emerged in the last two decades, the maize seed market in Kenya remains dominated by the parastatal seed company Kenya Seed Company, with multinational seed companies making major inroads. We assess whether parastatal and multinational seed companies have captured Kenya’s seed laws to the detriment of local small and medium seed companies (‘regulatory capture’), negatively effecting competition and the capacity of local companies to introduce new varieties in the hybrid maize seed market. We conducted in-depth interviews based on legal clauses with maize seed companies active in Kenya, as well as interviews with regulators and stakeholders. Results show that local companies do not feel disadvantaged compared to their multinational counterparts or the parastatal. However, all of them are wary of the entry of new actors. Moreover, through excessive procedures, the Kenyan government keeps a sovereign grasp over the seed sector. Despite frustrations with some of these excessive procedures, seed companies felt comfortable in the protective environment of the Kenyan seed market and were generally happy with the technical aspects of Kenya’s seed laws, which are based on international norms. We suggest some improvements to make Kenyan seed laws more conducive to varietal turnover, in line with seed companies’ suggestions and taking into account the political sensitivities of the Kenyan government.
One-dimensional inverse problems of determining the kernel of the integro-differential heat equation in a bounded domain
Authors: Durdiev Durdimurod Kalandarovich , Jumaev Jonibek Jamolovich 
Published: March 2023

Abstract
The integro-differential equation of heat conduction with the time-convolution integral on the right side is considered. The direct problem is the initial-boundary problem for this integro-differential equation. Two inverse problems are studied for this direct problem consisting in determining a kernel of the integral member on two given additional conditions with respect to the solution of the direct problems, respectively. The problems are replaced with the equivalent system of the integral equations with respect to unknown functions and on the basis of contractive mapping the unique solvability inverse problem.
Geopolitical Risk and Energy Market
Authors: Hudecova Kristina , Rajcaniova Miroslava 
Published: March 2023

Abstract
The fundamental aim of this paper is to test the symmetric and asymmetric effects of geopolitical risk on the five selected prices of energy commodities, consisting of coal, crude oil, gasoline, heating oil, and natural gas, during the period 2 January 2020–29 July 2022 by application of linear and nonlinear ARDL models. Moreover, we also study the impact of anticipated financial volatility on energy commodities. Our results suggest that, over the long term, there is no linear relationship between geopolitical risk, financial volatility, and energy prices. On the other hand, we find statistically significant asymmetrical effects of geopolitical risk and financial volatility on crude oil, gasoline, and heating oil prices in the long and short run. We also identify that coal and natural gas prices do not respond to changes in geopolitical risk during the analysed period.
The EGFR phosphatase RPTPγ is a redox‐regulated suppressor of promigratory signaling
Authors: Joshi Maitreyi S , Stanoev Angel , Huebinger Jan , Soetje Birga , Zorina Veronika , Roßmannek Lisaweta , Michel Kirsten , Müller Sven AH , Bastiaens Philippe IH 
Published: March 2023

AbstractSpatially organized reaction dynamics between proto‐oncogenic epidermal growth factor receptor (EGFR) and protein tyrosine phosphatases determine EGFR phosphorylation dynamics in response to growth factors and thereby cellular behavior within developing tissues. We show that the reaction dynamics of mutual inhibition between RPTPγ phosphatase and autocatalytic ligandless EGFR phosphorylation enable highly sensitive promigratory EGFR signaling responses to subnanomolar EGF levels, when < 5% receptors are occupied by EGF. EGF thereby triggers an autocatalytic phospho‐EGFR reaction by the initial production of small amounts of phospho‐EGFR through transient, asymmetric EGF‐EGFR2 dimers. Single cell RPTPγ oxidation imaging revealed that phospho‐EGFR induces activation of NADPH oxidase, which in turn inhibits RPTPγ‐mediated dephosphorylation of EGFR, tilting the autocatalytic RPTPγ/EGFR toggle switch reaction towards ligandless phosphorylated EGFR. Reversibility of this reaction to EGF is maintained by the constitutive phosphatase activity of endoplasmic reticulum‐associated TCPTP. This RPTPγ/EGFR reaction at the plasma membrane causes promigratory signaling that is separated from proliferative signaling induced by accumulated, liganded, phosphorylated EGF‐EGFR in endosomes. Accordingly, loss of RPTPγ results in constitutive promigratory signaling from phosphorylated EGFR monomers. RPTPγ is thus a suppressor of promigratory oncogenic but not of proliferative EGFR signaling.
Musicoterapia y trastorno específico del lenguaje / Music therapy and specific language disorder
Authors: Herrero Gómez María , Pérez Eizaguirre Miren 
Published: March 2023

El Trastorno Específico del Lenguaje (TEL) es uno de los problemas que más repercusiones tiene a nivel educativo e incluso, socio-cultural. Se ha descubierto que la musicoterapia puede ser una ayuda para la mejora de niños con esta dificultad de lenguaje. Son muchos los beneficios que la musicoterapia puede conseguir a nivel de expresión y comprensión, pero también a nivel personal del paciente. Los distintos planos de la música se adaptan perfectamente a los diferentes planos del lenguaje, facilitando el desarrollo del mismo, por lo que produce una gran mejoría. Además la música es capaz de suplir la falta de lenguaje permitiendo la expresión emocional del niño cuando este aún no encuentra palabras para expresarse. Se plantean dos ejemplos de sesiones para dar una idea de intervención.Palabras clave: TEL (Trastorno Específico del Lenguaje), musicoterapia, expresión oral, comprensión oral.AbstractThe Specific Language Impairment (SLI) is one of the problems with more education impact and also, socio-cultural one. It has been discovered that the musictherapy can be a helpful to get improvements in children with this language difficulty. Not only the benefits that can be achieved by the musictherapy in the speaking and listening skills are huge, but also in the patient’s personal level. The different music levels can be perfectly adapted to the different language levels, facilitating its development and producing a great improvement in the children’s language. Moreover, the music is able to compensate for children’s lack of verbal language, allowing them to express their emotions when they can’t still find words to do it. Two examples of sessions are shown to give an idea of intervention.Key words: SLI (Specific Language Impairment), musictherapy, speaking, listening.
Caregiver and Clinician Perspectives on Discharge Medication Counseling: A Qualitative Study
Authors: Carroll Alison R. , Schlundt David , Bonnet Kemberlee , Mixon Amanda S. , Williams Derek J. 
Published: March 2023

OBJECTIVES
Children are at increased risk for medication errors and the transition from hospital-to-home is a vulnerable time for errors to occur. This study aimed to explore the perspectives of multidisciplinary clinicians and caregivers regarding discharge medication counseling and to develop a conceptual model to inform intervention efforts to reduce discharge medication dosing errors.

METHODS
We conducted semistructured interviews with clinicians and caregivers of children &lt;4 years old discharged from the hospital on a liquid medication. A hierarchical coding system was developed using the interview guide and several transcripts. Qualitative analysis employed an iterative inductive-deductive approach to identify domains and subthemes and inform a conceptual framework.

RESULTS
We conducted focus groups and individual interviews with 17 caregivers and 16 clinicians. Using the Donabedian structure-process-outcomes model of quality evaluation, domains and subthemes included: (1) infrastructure of healthcare delivery, including supplies for counseling, content and organization of discharge instructions, clinician training and education, roles and responsibilities of team members, and hospital pharmacy delivery and counseling program; (2) processes of healthcare delivery, including medication reconciliation, counseling content, counseling techniques, and language barriers and health literacy; and (3) measurable outcomes, including medication dosing accuracy and caregiver understanding and adherence to discharge instructions.

CONCLUSIONS
The conceptual model resulting from this analysis can be applied to the development and evaluation of interventions to reduce discharge medication dosing errors following a hospitalization. Interventions should use a health literacy universal precautions approach—written materials with plain language and pictures and verbal counseling with teach-back and show-back.
The redistributive effect of the Hungarian flat tax and family allowance system
Authors: Krekó Judit , Erős Hanna , Greskovics Bori , Hajnal Áron , Scharle Ágota 
Published: March 2023

AbstractThe study examines the income redistribution effects of the Hungarian flat-tax and the recently introduced family allowance scheme. They were done on the basis of people's individual data for 2007, 2011 and 2020, which yields more accurate estimates than the previous studies based on aggregate or survey data. Between 2011 and 2013, progressive taxation was abolished, and a flat income tax was introduced, along with a substantial widening of pre-existing family tax allowances. We find that the tax reform has favoured high-income earners and taxpayers with children, while the main losers were low-income and/or childless workers. While the share of family tax allowances is somewhat lower for the high-income deciles, this effect is in practice negligible, therefore the income tax system can still be considered flat. The family tax allowance scheme favours wealthy families with many children over low-income families with fewer or no children. The biggest winners of the scheme are the taxpayers in the top income decile with three or more children: these 22,000 taxpayers (that is, 2% of all recipients) receive 10% of the total amount of the family tax allowance, and almost a third of the credit allocated to families with three or more children.
Bond durability between anchored GFRP bar and seawater concrete under offshore environmental conditions
Authors: Kazemi Hamidreza , Yekrangnia Mohammad , Shakiba Milad , Bazli Milad , Vatani Oskouei Asghar 
Published: March 2023

AbstractThe lower bond strength of FRP bars to concrete compared to steel bars has remained an unsolved barrier to the widespread use of FRP-reinforced concrete under extreme loading. Additionally, the degradation of the bond between FRP reinforcement and concretes in aggressive environments adds to the existing concern. In this study, an innovative anchorage system comprised of polypropylene pipe was used to strengthen the bond between seawater concrete and GFRP bars after 250 days of exposure to offshore environmental conditions. As material factors, two types of GFRP bars (sand-coated and ribbed) and two types of concrete (normal and seawater concrete) were evaluated. Four distinct environmental conditions were used to assess the samples: (i) ambient environment (control), (ii) tap water, (iii) seawater, and (iv) wet-dry cycles in seawater. According to the findings of the direct pull-out tests, the suggested anchor system strengthens the bond and shifts the failure mode from bond failure to bar rupture. Additionally, after exposure to 250 days of seawater wet-dry cycles, GFRP-reinforced seawater concrete lost 5% of its maximum bond strength (developed bar tensile stress). All other samples exposed to different environmental conditions either increased or decreased in bond strength by less than 5% after 250 days, compared to the control samples.
Potential clinical application of the cancer antigen CA‑62 for differential diagnosis of prostate cancer and benign prostatic hyperplasia at the elevated prostate‑specific antigen
Authors: Cherkasova Zh. R. , Tsurkan S. A. , Prostyakova A. I. , Boroda A. M. , Rozhkov A. A. , Pirogova Yu. N. , Nikitina N. M. , Sekacheva M. I. 
Published: March 2023

Purpose of the study. Evaluation of the diagnostic characteristics of the CA‑62 marker for epithelial carcinomas for detecting early‑stage prostate cancer in a double‑blind clinical study. This study is also focused on the possibility of using the CA‑62 antigen as an auxiliary tool for decision‑making in prostate cancer diagnosis.Patients and methods. A blinded clinical study was conducted on 325 clinically verified blood serum samples. This includes 144 prostate cancer samples, 79 generally healthy volunteers‑men and 102 samples from patients with benign prostatic hyperplasia (BPH). Quantitative determination of the total and free prostate specific antigen (PSA) levels, as well as the CA‑62 marker of serum samples was performed using the electrochemiluminescent immunoassay ECLIA Elecsys Total and Free PSA (COBAS, Roche Diagnostics GmbH, Germany, EU) and the chemiluminescent immunoassay CLIA‑CA‑62 (JVS Diagnostics LLC, Moscow, RF).Results. A comparison of the CA‑62 level with the results for total and free PSA, as well as other diagnostic methods (PCA3, PHI) for the analysis of the BPH and prostate cancer groups was performed. The results show that the CA‑62 marker has the highest PPV (94.4 %) and NPV (93.1 %). This may increase the reliability of the decision related to the presence of PC and be used by doctors as an argument as an argument for a prostate biopsy referral. It has been demonstrated that using the novel cancer marker CA‑62 makes it possible to detect up to 90 % of the early‑stage prostate cancer with 97.2 % specificity (AUC = 0.969).Conclusion. Using the CA‑62 marker as an auxiliary diagnostic method within the PSA “grey zone” (from 2.5 to 10 ng/ml) made it possible to significantly increase the accuracy of detecting the PC early stages at biopsy up to 93.1 %. It will help the doctors to effectively differentiate between prostate cancer and benign prostatic hyperplasia.
Effect of dendritic cell vaccine on blood redox status in patients with cervical cancer
Authors: Menshenina A. P. , Goroshinskaya I. A. , Frantsiyants E. M. , Moiseenko T. I. , Verenikina E. V. , Kaplieva I. V. , Nemashkalova L. A. 
Published: March 2023

Purpose of the study. The purpose of the study was to evaluate the dynamics of parameters of malondialdehyde (MDA), reduced glutathione and antioxidant enzyme activity in patients with advanced cervical cancer (CC) receiving anticancer treatment with dendritic cell vaccine (DCV).Patients and methods. Levels of malondialdehyde (MDA), reduced glutathione and antioxidant enzyme activity were studied in 27 patients aged 27–65 years with advanced primary and recurrent CC receiving chemotherapy (CT) with DCV or DCV as monotherapy at a dose of 10 million cells intradermally once a week. The same indices were studied in 20 healthy women from the comparison group.Results. The majority of patients showed the initial increase of MDA: in blood plasma by an average of 66.7 %, in red blood cells – statistically insignificant. After CT, MDA levels were elevated respectively in primary and recurrent patients in erythrocytes by 85.6 % and 96.4 % compared to donors, and by 53.9 % and 33.7 % compared to the initial values; the levels in plasma were elevated by 79.8 % and 57.1 % compared to donors. After 5–7 DCVs in combination with CT, MDA levels in erythrocytes and in blood plasma were similar to the donor values. MDA in erythrocytes of patients receiving DCV without CT decreased by 36 % compared to initial values. Oxidase activity of ceruloplasmin, initially increased by 34.2–57.1 %, normalized after DCV. Superoxide dismutase activity decreased by 16.7–27.3 % after 4–6 DCVs and normalized after 7 DCVs. Catalase activity, initially reduced by more than 40 %, remained 20–38 % lower than the norm at all stages of DCV. In this setting, hydrogen peroxide was probably inactivated by glutathione peroxidase whose activity was increased at all stages of treatment and decreased only when MDA was normalized after 7 DCVs.Conclusion. Administration of 5–7 DCVs in combination with CT or as monotherapy to patients with advanced CC normalizes parameters of free radical oxidation and antioxidant system of the blood.
La importancia de un enfoque integral del riesgo cardiovascular en el medio ambiente laboral
Authors: Gómez Vélez Diego Fernando 
Published: March 2023

El origen de la enfermedad cardiovascular se ha asociado con factores de riesgo como el sobrepeso, la hipertensión arterial, las dislipidemias, la diabetes mellitus, el tabaquismo, la inactividad física, la edad y la historia familiar de enfermedad cardiovascular, entre otros. Estudios científicos relacionan también factores de riesgo del medio laboral, como agentes químicos, factores físicos, agentes biológicos y factores psicosociales, con efectos adversos sobre el sistema cardiovascular o enfermedad cardiovascular.
En este artículo se busca generar reflexión en la comunida científica sobre los efectos cardiovasculares de factores de riesgo laborales que pueden ser significativos, a menudo subestimados y obligan a incluir en la prevención de la enfermedad cardiovascular en la empresa la identificación, el monitoreo y control de estos.