bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anatomical Study and Clinical Application of Optic Canal Decompression Via Transethmoid-sphenoid Approach Under Endoscope
Authors: Wang Xingdong , Zhang Hengzhu , She Lei , Wang Xiaodong , Yan Zhengcun , Wei Min , Tang Can 
Published: April 2023

This study aimed to evaluate the safety and accuracy of the endoscopic transethmoid-sphenoid approach for optic canal decompression. Twelve sides of 6 adult cadaveric heads fixed in formalin were selected to simulate optic canal decompression using the endoscopic transethmoid-sphenoid approach. Furthermore, this approach was used for optic canal decompression in 10 patients (11 eyes) with optic nerve canal injury. Related anatomical structures were observed using a 0-degree endoscope, and the anatomical characteristics as well as the surgical data were collected. The maximum effective widths of the cranial opening, orbital opening, and middle segment of the canal that could be drilled open endoscopically were 7.82±2.63, 8.05±2.77, and 6.92±2.01 mm, respectively. The angle between the line linking the center point of the tubercular recess with the midpoint of the cranial opening of the optic canal and the horizontal coordinate was 17.23±1.34 degrees. At the orbital opening of the optic canal, the ophthalmic artery was located directly inferior to the optic nerve in 2 cases (16.7%) and laterally inferior to the optic nerve in 10 cases (83.3%). Six of the operational eyes were effective while the remaining 5 were ineffective. No postoperative complications such as bleeding, infection, or cerebrospinal fluid leakage were observed during the follow-up period (6–12 mo). In conclusion, optic canal decompression positively impacts the prognosis of partial traumatic optic neuropathy. Furthermore, the endoscopic transethmoid-sphenoid approach for optic canal decompression is a minimally invasive procedure that provides direct access and adequate decompression. This technique is easy to master and suitable for clinical applications.
Analysis of Survival Quality of Peroneal Artery Perforator Flap in Immediate Repairment and Reconstruction of Oral and Maxillofacial Malignancies
Authors: Song Peijun , Liang Qiu , Qian Yunzhu , Li Jiancheng 
Published: April 2023

Objective:
This study aimed to investigate the survival quality of peroneal artery perforator flap in the reconstruction of oral and maxillofacial malignant tumors.

Methods:
Thirty-two cases with a diagnosis of oral and maxillofacial malignant tumors admitted to our hospital from January 2019 to December 2019 were randomly divided into 2 groups. The observation group was reconstructed with free open artery perforator flaps, and the control group was repaired with free forearm flaps.

Results:
The observation group had significantly lower scores in terms of postoperative pain, appearance, and anxiety, compared with the control group (P<0.05). Both groups had high scores on taste, saliva, and shoulder function although there was no significant difference (P>0.05). The scores of the observation group were significantly higher than those in the control group in terms of chewing, swallowing, speech, activity, mood, and entertainment (P<0.05). There was 1 case accompanied by postoperative wound dehiscence and 2 cases with wound infection in the observation group while there were 3 cases with wound dehiscence and 2 cases with wound infection in the control group (P>0.05).

Conclusion:
Compared with the forearm flap, the peroneal artery perforator flap can improve the survival quality of patients, especially in postoperative function with the fibula joint to repair the oral and maxillofacial defects. It has a wide application prospect as one of the ideal flaps in oral and maxillofacial postoperative repair and reconstruction.
Severity Grading Systems for Intraoperative Adverse Events. A Systematic Review of the Literature and Citation Analysis
Authors: Sayegh Aref S. , Eppler Michael , Sholklapper Tamir , Goldenberg Mitchell G. , Perez Laura C. , La Riva Anibal , Medina Luis G. , Sotelo Rene , Desai Mihir M. , Gill Inderbir , Jung James J. , Kazaryan Airazat M. , Edwin Bjørn , Biyani Chandra Shekhar , Francis Nader , Kaafarani Haytham MA , Cacciamani Giovanni E. 
Published: April 2023

Introduction:
The accurate assessment and grading of adverse events (AE) is essential to ensure comparisons between surgical procedures and outcomes. The current lack of a standardized severity grading system may limit our understanding of the true morbidity attributed to AEs in surgery. The aim of this study is to review the prevalence in which intraoperative adverse event (iAE) severity grading systems are used in the literature, evaluate the strengths and limitations of these systems, and appraise their applicability in clinical studies.

Methods:
A systematic review was conducted in accordance with PRISMA guidelines. PubMed, Web of Science, and Scopus were queried to yield all clinical studies reporting the proposal and/or the validation of iAE severity grading systems. Google Scholar, Web of Science, and Scopus were searched separately to identify the articles citing the systems to grade iAEs identified in the first search.

Results:
Our search yielded 2957 studies, with 7 studies considered for the qualitative synthesis. Five studies considered only surgical/interventional iAEs, while two considered both surgical/interventional and anesthesiologic iAEs. Two included studies validated the iAE severity grading system prospectively. A total of 357 citations were retrieved, with an overall self/non-self-citation ratio of 0.17 (53/304). The majority of citing articles were clinical studies (44.1%). The average number of citations per year was 6.7 citations for each classification/severity system, with only 2.05 citations/year for clinical studies. Of the 158 clinical studies citing the severity grading systems, only 90 (56.9%) used them to grade the iAEs. The appraisal of applicability (mean%/median%) was below the 70% threshold in 3 domains: stakeholder involvement (46/47), clarity of presentation (65/67), and applicability (57/56).

Conclusion:
Seven severity grading systems for iAEs have been published in the last decade. Despite the importance of collecting and grading the iAEs, these systems are poorly adopted, with only a few studies per year using them. A uniform globally implemented severity grading system is needed to produce comparable data across studies and develop strategies to decrease iAEs further improving patient safety.
Liver Transplantation vs Partial Hepatectomy for Stage T2 Multifocal Hepatocellular Carcinoma <3 cm Without Vascular Invasion: A Propensity Score-Matched Survival Analysis
Authors: Wong Linda L , Landsittel Douglas P , Kwee Sandi A 
Published: April 2023

BACKGROUND:
Multifocal hepatocellular carcinoma (HCC) differs biologically and immunologically from single-nodule HCC. Asian and European guidelines consider liver transplantation (LT) and partial hepatectomy (PH) as effective for T2 multifocal HCC, with preference toward LT, but few US studies compare these treatments directly. This propensity score–based observational study uses an established national cancer outcomes registry to compare overall survival in patients undergoing PH and LT for multifocal HCC.

STUDY DESIGN:
Data from the 2020 National Cancer Database were obtained on patients who underwent LT or PH for multifocal stage 2 HCC within Milan criteria and without vascular invasion. Propensity score matching and Cox regression analysis was applied to evaluate overall survival in an observational cohort balanced by age, sex, treatment facility type, treatment year, prothrombin time, α-fetoprotein, comorbidity burden, liver fibrosis severity, and pretreatment creatinine and bilirubin levels.

RESULTS:
Of 21,248 T2 HCC patients identified, 6,744 had multifocal tumors with largest tumor diameter <3 cm without major vascular invasion, with 1,267 and 181 having undergone LT and PH, respectively. Propensity score–matched Cox regression analysis associated LT with a hazard ratio of 0.39 (95% CI 0.30 to 0.50) relative to PH. Landmark analyses to account for a longer interval to LT demonstrated survival benefits of similar magnitude.

CONCLUSIONS:
Although early-stage HCC can be effectively treated with either LT or PH, propensity score–matched analysis comparatively shows a survival benefit for LT in patients with multifocal HCC who are within the Milan criteria.
Pseudoaneurysm after High-Grade Penetrating Solid Organ Injury and Utility of Delayed CT Angiography
Authors: Schellenberg Morgan , Owattanapanich Natthida , Emigh Brent , Nichols Chance , Dilday Joshua , Ugarte Chaiss , Onogawa Atsushi , Matsushima Kazuhide , Martin Matthew J , Inaba Kenji 
Published: April 2023

BACKGROUND:
Leaving an injured solid organ in situ allows preservation of structure function but invites complications from the damaged parenchyma, including pseudoaneurysms (PSAs). Empiric PSA screening after solid organ injury is not yet established, particularly following penetrating trauma. The study objective was definition of delayed CT angiography (dCTA) yield in triggering intervention for PSA after penetrating solid organ injury.

METHODS:
Penetrating trauma patients at our American College of Surgeons–verified level 1 center with American Association for the Surgery of Trauma grade ≥3 abdominal solid organ injury (liver, spleen, kidney) were retrospectively screened (January 2017 to October 2021). Exclusions were age <18 y, transfers, death within <48 h, and nephrectomy/splenectomy within <4 h. Primary outcome was intervention triggered by dCTA. Statistical testing with ANOVA/chi-square compared outcomes between screened vs unscreened patients.

RESULTS:
A total of 136 penetrating trauma patients met study criteria: 57 patients (42%) screened for PSA with dCTA and 79 (58%) unscreened. Liver injuries were most common (n = 41, 64% vs n = 55, 66%), followed by kidney (n = 21, 33% vs n = 23, 27%) and spleen (n = 2, 3% vs n = 6, 7%) (p = 0.48). Median American Association for the Surgery of Trauma grade of solid organ injury was 3 (3 to 4) across groups (p = 0.75). dCTA diagnosed 10 PSAs (18%) at a median of hospital day 5 (3 to 9). Among screened patients, dCTA triggered intervention in 17% of liver patients, 29% of kidney patients, and 0% of spleen-injured patients, for an overall yield of 23%.

CONCLUSIONS:
Half of eligible penetrating high-grade solid organ injuries were screened for PSA with dCTA. dCTA identified a significant number of PSAs and triggered intervention in 23% of screened patients. dCTA did not diagnose any PSAs after splenic injury, although sample size hinders interpretation. To avoid missing PSAs and incurring their risk of rupture, universal screening of high-grade penetrating solid organ injuries may be prudent.
Risk analysis of public-private partnership waste-to-energy incineration projects in China: a hybrid fuzzy DEMATEL-ISM approach
Authors: Cheng Min , Liu Lin , Cheng Xiaotong , Tao Li 
Published: April 2023

PurposeMany waste-to-energy (WTE) plants are constructed and operated using the public-private partnership (PPP) mode in China. However, risk events of PPP WTE incineration projects sometimes occur. This study aims to clarify the relationship of risks in China's PPP WTE incineration projects and identify the key risks accordingly and risk transmission paths.Design/methodology/approachA risk list of PPP WTE incineration projects was obtained based on literature analysis. Moreover, a hybrid approach combining fuzzy sets, decision-making trial and evaluation laboratory (DEMATEL) and interpretive structural modeling (ISM) was developed to analyze the causality of risks, explore critical risks and reveal the risk transmission paths. The quantitative analysis process was implemented in MATLAB.FindingsThe results show that government decision-making risk, government credit risk, government supervision behavior risk, legal and policy risk, revenue and cost risk and management capacity risk are the critical risks of PPP WTE incineration projects in China. These critical risks are at different levels in the risk hierarchy and often trigger other risks.Originality/valueCurrently, there is a lack of exploration on the interaction between the risks of PPP WTE incineration projects. This study fills this gap by examining the key risks and risk transfer pathways of PPP WTE incineration projects from the perspective of risk interactions. The findings can help the public and private sectors to systematically understand the risks in PPP WTE incineration projects, thus enabling them to identify the risks that need to be focused on when making decisions and to optimize risk prevention strategies. The proposed hybrid approach can offer methodological ideas for risk analysis of other types of PPP projects.
The Anthropocene and the sustainable development goals: key elements in geography higher education?
Authors: Martínez-Hernández Carlos , Mínguez Carmen 
Published: April 2023

Purpose
The current “Anthropocene” epoch has witnessed an imbalanced global change, but it is an opportunity to design a better and sustainable future. Sustainability criteria need to be fully implemented in political institutions, companies and universities. Moreover, sustainable pedagogies must accompany the process in terms of students’ professional competences to overcome crisis situations. This paper aims to evaluate geography degrees in Spain to corroborate whether students and teachers consider that students are prepared to address the challenges of global change.

Design/methodology/approach
The research is focused on the sustainable development goals (SDGs), a clear and easily identifiable framework for society that reflects the principles of the UN 2030 Agenda. A statistically validated questionnaire answered by 319 respondents has been used. Data analysis with descriptive and inferential techniques was performed.

Findings
The results show that geography degrees do not meet the needs of students, for whom career opportunities will be related to the implementation of the 2030 Agenda; there are significant gaps between the perception of teachers and students; some geographical topics are undervalued; SDGs are more present in optional subjects; and there is a need to “sustain” the curriculum, following this highly valued framework.

Originality/value
Geography educative programs had scarcely been empirically evaluated to check a sustainability framework implementation. This research provides innovative and unprecedented self-assessment results from higher education agents, in an empirical and statistically validated way.
COVID‐19 vaccine–associated vitiligo: A cross‐sectional study in a tertiary referral center and systematic review
Authors: Tsai Tsung‐Fu , Ng Chau Yee 
Published: April 2023

AbstractAs the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus continues to infect patients globally, vaccination remains one of the primary methods to combat this prolonged pandemic. However, there are growing reports of coronavirus disease 2019 (COVID‐19) vaccines possibly triggering autoimmunity, irrespective of the vaccine's design. This phenomenon has been observed in patients with vitiligo, with a rising number of cases reporting new‐onset or worsening vitiligo following COVID‐19 vaccinations. In this study, the authors present the most extensive case series of COVID‐19 vaccine–associated vitiligo to date, along with a systematic review of the literature. The aim is to assist physicians in the clinical evaluation of patients with vitiligo with regard to future vaccinations.
Clean energy, clean water, and quality education: Prospects of achieving Sustainable Development Goals (SDGs) in Sri Lanka
Authors: Wijayarathne J. M. D. Sandamali , Hassan Gazi M. , Holmes Mark J. 
Published: April 2023

AbstractThe Sustainable Development Goal (SDG) 7 targets universal access to affordable, reliable, and modern energy services by 2030. Modern or clean energy is perceived to be the golden thread that connects economic growth, human development, and environmental sustainability. However, one third of the world's population still uses solid fuels for cooking, endangering human health, and the environment. This paper, therefore, analyses demographic, socio‐economic, and housing characteristics that affect the fuel choice for cooking. Further, it identifies how SDG 4 (quality education) and SDG 6 (clean water) create synergies with SDG 7 (clean energy). The data are obtained from the four waves of the Sri Lankan Households Income and Expenditure Survey, covering more than 79,000 households. The random‐effects panel multinomial logit results reveal that household income, wealth, marital status and education of the head, age and education of the spouse, household size, number of children, housing characteristics, and residential sector are vital in selecting clean fuel for cooking. Furthermore, advanced sustainability analysis shows SDG 4 and 6 have a strong synergistic effect on SDG 7. Policymakers can use the findings to prioritise educational, water, and sanitation programmes in national policies aimed at enhancing the use of clean cooking fuel and technologies to meet SDG 7 by 2030.
¿Los índices biológicos de calidad son universalmente útiles? Límites de los índices basados en bentos en una subcuenca salobre y árida de Argentina
Authors: Alvarez Dalinger Florencia Soledad , Lozano Verónica Laura , Moraña Liliana , Borja Claudia Nidia , Salusso Mónica 
Published: April 2023

ResumenSe evaluó la calidad del agua de los ríos de una subcuenca árida del norte de Argentina en un gradiente longitudinal, durante el período de sequía máxima de 2017. Se estudió la composición y estructura del fitobentos mediante índices bióticos. Se determinaron 126 spp. en total, con predominio de diatomeas y cianobacterias. La mayoría de las especies de diatomeas encontradas eran de meso a polihalobas y tolerantes a la contaminación orgánica. A pesar de que los ríos de la cuenca atraviesan zonas con usos de la tierra muy diferentes, no se registraron diferencias en las abundancias de fitobentos entre los sitios. Según el Índice de Saprobiedad de Pantle & Buck, la subcuenca se clasificó en el rango de α‐mesosaprobiedad, y el Índice de Eutrofización/Contaminación por Diatomeas asigna una calidad baja a la mayoría de los sitios. La salinidad debe inducir una homogeneización de la ficoflora que limita la sensibilidad de los índices bióticos a los impactos antropogénicos.
Clinical and dermoscopic features of nail unit melanoma in an Australian nail clinic cohort
Authors: Arasu Alexis , Howard Anne , Tan Chin‐Guan , Prakash Saurabh , Kern Johannes S. 
Published: April 2023

AbstractNail unit melanoma carries diagnostic challenges conferring with its poor prognosis. This audit aims to characterise both clinical and dermoscopic features of nail unit malignant lesions and compare them with biopsied benign lesions. It focuses on informing future practice by aiding in the stratification and recognition of malignant diagnostic patterns in the Australian context.
The simultaneous occurrence of livedoid vasculopathy and lymphocytic thrombophilic arteritis in six cases
Authors: Kelly Robert , Gan Christian , Ting Sarajane , Manuelpallai Nicholas , Wee Edmund 
Published: April 2023

AbstractLymphocytic thrombophilic arteritis and livedoid vasculopathy may both present with livedo racemosa and ulceration. We present 6 cases with features of both conditions, raising the possibility that they are either closely linked or are part of a spectrum of the same condition.
Ethnonationalist Gender Norms: How Parties Shape Voter Attitudes toward Female Candidates in India
Authors: Thomas Anjali , Banerjee Sayan , Hankla Charles , Banerjee Arindam 
Published: April 2023

AbstractHow do parties in multiethnic societies shape voter attitudes toward female candidates? We address this question, focusing on parties with ideologies that contain ethnonationalist gender norms—patriarchal norms applied to women from an ethnonationalist party's core ethnic constituency. We argue that, while these norms appeal to an ethnonationalist party's base, they also provide informational cues to the party's “non‐core” voters that undermine their support for the party's “core” female candidates. Evidence from an original conjoint survey experiment in the Indian state of Bihar supports our argument; upper‐caste female candidates suffer a support penalty when they are affiliated with the national ruling party, whose ideology prescribes ethnonationalist gender norms targeting its core Hindu upper‐caste constituency. This penalty, we show, is driven by the party's non‐core voters. Our results, which we further bolster using real‐world electoral data, illuminate when and how ethnonationalist gender norms disadvantage elite female candidates.
Emotional involvement matters, too: Associations among parental involvement, time management and academic engagement vary with Youth's developmental phase
Authors: Liu Sihan , Wang Xinyi , Ying Jiefeng , Shi Jialin , Wu Xinchun 
Published: April 2023

AbstractBackgroundPrior studies have emphasized the importance of parents' educational involvement (a type of cognitive involvement) to academic engagement, although little is known about emotional involvement.AimsThis study investigated whether and how different facets of involvement (cognitive vs. emotional, paternal vs. maternal) are differentially related to academic engagement and whether and how the associations among parental involvement, time management and academic engagement vary by adolescents' developmental phases.SamplesThe participants of this large national survey were students in elementary, middle and high school across different regions of mainland China. A total of 2687 adolescents (52.7% females, Mage = 14.07 ± 2.47) participated in this study.MethodsStructural equation models and multigroup analysis were conducted.ResultsWe found that the total effect of paternal and maternal emotional involvement on academic engagement was positive in elementary‐, middle‐ and high school students, and an indirect effect of time management underlying the above paths was found in all three groups. In contrast, the positive effect of maternal cognitive involvement on academic engagement as well as the indirect effects underlying the above pathways was established only in high school students.ConclusionsThe findings highlight the necessity of parents' emotional involvement and the consideration of adolescent developmental characteristics in the design of interventions.
Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR‐671‐5p/LGALS3BP/NF‐κB axis
Authors: Guo Kaixuan , Shi Juanyi , Tang Zhuang , Lai Cong , Liu Cheng , Li Kuiqing , Li Zhuohang , Xu Kewei 
Published: April 2023

AbstractCircular RNAs (circRNAs) play crucial roles in various biological processes, including prostate cancer (PCa). However, the precise roles and mechanism of circRNAs are complicated. Hence, we studied the function of a circRNA that might be involved in the progression of PCa. In this study, we found that circARHGEF28 was frequently downregulated in PCa tissues and cell lines. Furthermore, gain‐ and loss‐of function experiments in vitro showed that circARHGEF28 inhibited proliferation, migration, and invasion of PCa. Additionally, circARHGEF28 suppressed PCa progression in vivo. Bioinformatics analysis and RNA pull‐down and capture assay found that circARHGEF28 sponged miR‐671‐5p in PCa cells. Importantly, qRT‐PCR and dual luciferase assays found that Lectin galactoside‐binding soluble 3 binding protein (LGALS3BP) was downstream of miR‐671‐5p, and western blot analysis further confirmed that LGALS3BP negatively regulated the nuclear factor kappa‐B (NF‐κB) pathway. These results demonstrated that circARHGEF28 abolished the degradation of LGALS3BP by sponging miR‐671‐5p, thus blocking the activation of the NF‐κB pathway. Our findings revealed that circARHGEF28/miR‐671‐5p/LGALS3BP/NF‐κB may be an important axis that regulates PCa progression.