bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of logistics costs of the enterprise
Authors: Plekan Uliana , Tson Oleg , Gevko Bogdan , Antoniuk Oleh 
Published: September 2023

The article examines the problems of the operation of the enterprise's logistics system, which are relevant and require immediate resolution by optimizing logistics costs and improving the operation of this system as a whole. The connection between the optimization of logistics costs and the strengthening of the company's competitive advantages due to the successful selection of contractors, optimal product distribution channels, modeling of logistics systems and chains, and the creation of conditions for resource conservation is substantiated. The quality of logistics processes is reflected in the effective indicators of the transport company's activity, as costs aimed at the use of labor, means and labor items are minimized.
The logistics system of a modern company is increasingly becoming the subject of scientific research and development as a key form of automation, integration, optimization and management of material resources and information flows circulating in business units. The issue of optimization of logistics costs of production enterprises is characterized by incompleteness and requires further scientific research.
The quality of logistics processes is reflected in the effective indicators of the enterprise's activity due to the minimization of costs for the use of labor, funds and labor items. The main types of logistics costs were analyzed in the article. And also the need to determine the presence of hidden types of logistics costs was noted. It was outlined that the complexity of determining logistics costs is caused by the influence of internal and external environmental factors. Changes in the structure of logistics costs were analyzed based on the data of the investigated enterprise. The impact of labor costs on logistics workers of the selected enterprise was considered and the dynamics of costs associated with the provision of logistics services on the total amount of logistics costs was analyzed. It was determined that the relationship between the total logistics costs and the set of their factor characteristics is a close direct one. Correlation-regression analysis to identify influencing factors on the behavior of logistics costs of the analyzed enterprise was performed.
It was substantiated that the definition of factors and their influence on logistics costs make it possible to influence the costs of the enterprise and ensure the attractiveness of the product for consumers. The influence of logistics levers on the profitability of the enterprise was schematically displayed. The indicators of logistics cost management assessment, which provide an opportunity to form a qualitative description of the state of the enterprise's logistics system, were given in the article.
Siedem sztuk wyzwolonych w "Etymologiach" Izydora z Sewilli
Authors: Krynicka Tatiana , Wilczyński Adam 
Published: September 2023

Kanon siedmiu nauk wyzwolonych należy do szczytowych osiągnięć antycznej kultury. Starożytni myśliciele postrzegali je jako nauki godne człowieka wolnego, uprawiane w wolnym czasie, bez zaangażowania wysiłku fizycznego oraz nie w celu otrzymania korzyści materialnej. Dla autorów chrześcijańskich to nauki prowadzące do poznania prawdy, która wyzwala; Kasjodor podkreśla, że są one przekazywane w książkach oraz stwierdza, że mają fundamentalne znaczenie dla rozwoju człowieka. Izydor z Sewilli również wprowadza swego czytelnika w świat wiedzy o Stwórcy i stworzeniu przez bramy siedmiu nauk wyzwolonych, którym poświęca pierwsze trzy księgi Etymologii. Centralne miejsce w jego wykładzie zajmuje gramatyka (ks. 1); studium nauk literackich (ks. 1-2) jest bardziej szczegółowe niż prezentacja dyscyplin matematycznych (ks. 3). Wykład materiału, zaczerpniętego z pism poprzedników, jest przemyślany, usystematyzowany, poniekąd oryginalny (ks. 1); choć w niektórych partiach (zwłaszcza tych poświęconych gramatyce) niekiedy chaotyczny i niespójny. Podsumowanie roli poszczególnych nauk wyzwolonych dokonane zostaje w końcowym rozdziale ks. 4, traktującej o medycynie.
Praktek Edukasi Spiritual Kaum Difabel Lewat Pembelajaran Alkitab di Sentra Efata Kupang
Authors: Saefatu Meyrlin , Nigha Johanes Marno , Kabnani Simon , Taopan Mayenti , Maukoni Alexander J. 
Published: September 2023

Kegiatan Pengabdian kepada Masyarakat di Sentra Efata Kupang ini bertujuan untuk memberikan pelatihan dan pendalaman tentang pembelajaran Alkitab serta beragam media pembelajaran untuk melayani pendampingan spiritual anak difabel. Adapun metode yang digunakan yaitu lewat praktek edukasi spiritual kaum difabel melalui pembelajaran Alkitab bagi anak difabel yang dilaksanakan dengan menggunakan metode ceramah, diskusi dan praktek dalam bentuk teater. Sesi pertama diadakan dengan memberikan pemahaman kepada para peserta tentang bagaimana anak-anak kaum penyandang disabilitas menerima diri mereka berdasarkan bacaan Alkitab yang terambil dari Kitab Yeremia 1:5, dengan tema “Penerimaan Diri”. Setelah itu dilanjutkan dengan “Praktek Edukasi Spiritual”. Kegiatan tersebut diikuti oleh 65 orang yang terdiri dari 60 orang penerima manfaat (kaum disabilitas) dan tiga orang pendamping serta dua orang pembina kerohanian. Hasil kegiatan tersebut adalah anak-anak disabilitas memiliki pemahaman tentang diri mereka sebagai ciptaan Tuhan yang mulia dan unik, yang melalui keterbatasan mereka, Tuhan menitipkan kelebihan dalam dirinya. Kegiatan Pengabdian kepada Masyarakat telah terlaksana dengan baik dan mendapatkan antusias baik dari para penerima manfaat (kaum disabilitas) maupun dari para pendamping dan pembimbing rohani.
Uncovering the Morphological and Genetical Heterogeneity of Pyricularia oryzae (cooke) sacc. in Southwestern Region of Bangladesh
Authors: Sultana Mst. Sabiha , Ray Joyanti , Akther Papry , Mondal Debproshad , Mondal Chhoa 
Published: September 2023

Significant yield losses are reported due to blast disease caused by Pyricularia oryzae across all rice growing areas of the world. Though, management strategies reduce disease significantly but blast epidemics are still common. This research was aimed to determine the variability among the 19 Pyricularia oryzae isolates of South-Western regions of Bangladesh. Morphological variability was determined based on nine morphological components like front mycelial color, reverse mycelial color, growth behavior, conidial length (μm), conidial width (μm), conidial color, radial growth at 12 days (mm), 14 days (mm) and 16 days (mm) after incubation. Cluster analysis considering nine morphological components showed five distinct groups. Front and reverse mycelial color, growth behavior and conidial length played more than 80% role in generating variation among the nine tested components. Higher genetic variation was also detected among the 19 isolates of P. oryzae. Here, larger numbers of amplified DNA fragments was formed by Primers UCB-155 which showed distinct polymorphism. Between two clusters, Cluster II consists of 18 isolates that were originated from different origin but having maximum 94% genetical similarity. Cluster I contain only one isolates PO-16. From pair wise distance matrix, maximum distance (80%) was found between PO-16 and PO-03 isolates and minimum distance (6%) was obtained between the isolates PO-11 and PO-12. Results of this experiment revealed that, higher genetic diversity among isolates of P. oryzae existed in the south western region of Bangladesh but there has no direct relation with genetic diversity and geographical origin.
The association of hamstring tightness with lumbar lordosis and trunk flexibility in healthy individuals: gender analysis
Authors: Allam Nesma M. , Ebrahim Hasnaa Ali , Megahed Ibrahim Ateya , Elneblawi Nora Helmi , El-Sherbiny Mohamed , Fouda Khaled Zaki 
Published: September 2023

Objectives: The purpose of this study was to investigate if there is a relation between hamstring tightness and lumbar lordosis as well as trunk flexibility based on gender differences and to analyze the differences in hamstring tightness, lumber lordosis and trunk flexibility in healthy adults.Methods: One hundred young healthy adults were recruited and distributed into 2 equal groups according to gender: group A (female group) and group B (male group). Hamstring tightness (HT) was measured by Active Knee Extension (AKE) test and Straight Leg Raise (SLR) test, the angle of lumbar lordosis was measured with a flexible ruler from standing position and trunk flexion flexibility (TFF) was measured by Fingertip-to-Floor Test.Results: There was a significant correlation between TFF and both measures of HT (SLR, p = 0.001; AKE, p = 0.001) in females. While, there was a non-significant correlation in males (SLR, p = 0.900; AKE, p = 0.717). Moreover, there was a non-significant correlation between lumbar lordosis and HT measures in both groups as (p &gt; 0.05). Furthermore, there were significant differences between males and females in hamstring flexibility, TFF and lumbar lordosis as (p &lt; 0.05).Conclusion: Gender differences in the relationship between hamstring tightness and trunk flexion flexibility are significant. However, there was no significant difference between males and females in the relationship between hamstring tightness and lumbar lordosis.
Investigations into the effects of scaffold microstructure on slow-release system with bioactive factors for bone repair
Authors: Pei Baoqing , Hu Mengyuan , Wu Xueqing , Lu Da , Zhang Shijia , Zhang Le , Wu Shuqin 
Published: September 2023

In recent years, bone tissue engineering (BTE) has played an essential role in the repair of bone tissue defects. Although bioactive factors as one component of BTE have great potential to effectively promote cell differentiation and bone regeneration, they are usually not used alone due to their short effective half-lives, high concentrations, etc. The release rate of bioactive factors could be controlled by loading them into scaffolds, and the scaffold microstructure has been shown to significantly influence release rates of bioactive factors. Therefore, this review attempted to investigate how the scaffold microstructure affected the release rate of bioactive factors, in which the variables included pore size, pore shape and porosity. The loading nature and the releasing mechanism of bioactive factors were also summarized. The main conclusions were achieved as follows: i) The pore shapes in the scaffold may have had no apparent effect on the release of bioactive factors but significantly affected mechanical properties of the scaffolds; ii) The pore size of about 400 μm in the scaffold may be more conducive to controlling the release of bioactive factors to promote bone formation; iii) The porosity of scaffolds may be positively correlated with the release rate, and the porosity of 70%–80% may be better to control the release rate. This review indicates that a slow-release system with proper scaffold microstructure control could be a tremendous inspiration for developing new treatment strategies for bone disease. It is anticipated to eventually be developed into clinical applications to tackle treatment-related issues effectively.
Cardiovascular disease and risk factors in adults with diabetes mellitus in Hungary: a population-based study
Authors: Ulambayar Battamir , Ghanem Amr Sayed , Kovács Nóra , Trefán László , Móré Marianna , Nagy Attila Csaba 
Published: September 2023

IntroductionDiabetes mellitus (DM) and cardiovascular disease (CVD) such as acute myocardial infarction, stroke, and coronary artery disease are highly prevalent conditions that are responsible for significant morbidity and mortality, particularly in Hungary. The conditions are attributed to identical risk factors, and individuals with DM are primarily susceptible to cardiovascular complications, which are the leading causes of death and disability in patients with DM. The objective of this study was to estimate the prevalence of CVD in individuals with DM and to investigate the association between potential risk factors and the presence of CVD among individuals with DM in a population-based sample.MethodsThe study was based on data from three waves of the European Health Interview Surveys (EHIS) conducted in Hungary in 2009, 2014, and 2019.ResultsThe prevalence of CVD among patients with DM decreased during the study period and that socioeconomic factors, cardiometabolic risk factors including high blood pressure and high cholesterol, and depression are major contributors to CVD burden in patients with DM in Hungary.DiscussionOur findings suggest the importance of regular check-up for hypertension and hypercholesterolemia, better focus on socioeconomic status, as well as ongoing monitoring of mental health among patients with diabetes. Further research is needed to understand the potential causes behind the observed decrease in CVD prevalence.
A new type of high hardness coating for improving drill bit stability in unconventional oil and gas development
Authors: Xuan Lingchao , Wang Jiangshuai 
Published: September 2023

In deep unconventional oil and gas development, the problem faced is that PDC bits are eroded by solid-liquid high-speed fluids, resulting in damage. It has led to serious damage to the stability of the drill bit, a decrease in the service life of the drill bit, and an increase in the difficulty in efficient drilling. The essence is that the surface hardness and erosion resistance of the drill bit are not strong enough. Therefore, improving the stability of drill bits is a crucial and urgent problem to be solved. In this paper, Ni60A + 20% WC + 0.3% graphene composite coatings were prepared on a Q235 steel substrate, which is a new type of high hardness coating. Moreover, the effects of microstructure and microhardness of the composite coatings at different laser powers (800 W, 1200 W, 1600 W, and 2000 W) were investigated. The results show that the laser power can significantly affect the microstructure of the coating. The phase composition of the composite coatings is essentially the same at different laser powers. However, there are significant differences in the content of each phase. When the laser power is higher than 1200W, the content of M23C6, Cr3C2 and Fe3C in the composite coating increases and the microhardness of the coating decreases. When the laser power is below 1200 W, the dilution rate of the substrate is low and a metallurgical bond cannot be formed between the composite coating and the substrate.
Influence of 36 years of integrated nutrient management on soil carbon sequestration, environmental footprint and agronomic productivity of wheat under rice-wheat cropping system
Authors: Ranjan Shivani , Kumar Sanjay , Dutta Swaraj Kumar , Padhan Smruti Ranjan , Dayal Parmeswar , Sow Sumit , Roy Dhirendra Kumar , Nath Dibyajyoti , Baral Kirttiranjan , Bharati Vikram 
Published: September 2023

A long-term field experiment was conducted to study the effects of different combinations of integrated nutrient management (INM) on carbon sequestration and wheat yield in a rice-wheat cropping system. The experiment consisted of 11 treatments that were replicated three times. The organic manures used in the study included farmyard manure (FYM), wheat straw (WS), and green manure (GM) with Sesbania aculeata. The results of the experiment revealed that the application of 50% of the recommended dose of fertilizers (RDF) along with 50% nitrogen (N) through FYM during rice cultivation, and RDF during wheat cultivation, led to a significant increase in soil organic carbon (SOC). Specifically, the SOC content was enhanced by 46.4% (18.29 Mg ha-1) compared to RDF in rice and wheat, resulting in a C sequestration rate of 0.22 Mg ha-1 year-1. These increases were higher in treatments that combined organic and inorganic inputs. Additionally, the application of 50% RDF and substituting 50% of the nitrogen with FYM during wheat cultivation resulted in a 24.7% increase in grain yield compared to RDF in rice and wheat. The INM treatments, showed significantly (p ≤ 0.05) higher agronomic efficiency (AE) of nitrogen (N), phosphorus (P) and potassium (K), partial factor productivity (PFP) of N, P and K, and carbon pool index (CPI) compared to the application of inorganic fertilizers at the recommended dose. Moreover, the INM treatments also exhibited lower greenhouse gas (GHG) emission intensity. Application of neither chemical fertilizers nor organic manure (T1) resulted in maximum GHG emission intensity (328.1 kg CO2 eq Mg−1 yield). Based on these findings, it can be concluded that the combined use of inorganic fertilizers and organic manures significantly increased crop yield and soil organic carbon sequestration while reducing GHG emissions in a rice-wheat cropping system in the eastern Indo-Gangetic Plains (EIGP) of India.
Case report: De novo mutation of a-galactosidase A in a female patient with end-stage renal disease: report of a case of late diagnosis of Anderson–Fabry disease
Authors: Simonetta Irene , Riolo Renata , Todaro Federica , Donadio Vincenzo , Incensi Alex , Tuttolomondo Antonino 
Published: September 2023

Background: Anderson–Fabry disease (AFD) is an X-linked disease that results from reduced activity of the enzyme galactosidase alpha (GLA). When the GLA gene sequence is altered by mutations that alter the normal DNA sequence, variants of the alpha-galactosidase A enzyme are produced, which may or may not function. These mutations are responsible for Fabry disease, and to date, over 800 different mutations of the gene have been described in patients with Anderson–Fabry disease. In this case, we report the case of a woman who is the sole family member with this type of mutation.Case presentation: We report a case of a 52-year-old woman with end-stage chronic kidney disease in dialysis treatment. The patient’s alpha-galactosidase activity was 6.6 nmol/ml/h in whole blood, and lyso-GB3 levels were 11.45 nmol/L (normal range &lt; 2.3 nmol/L). Alpha-galactosidase A gene sequence analysis revealed a pathogenic variant of c.947dupT in exon 6, leading to the p. I317NfsTer16 amino acid substitution. The genetic analysis did not detect the same mutation in any of the other screened family members.Conclusion: The international Fabry disease genotype-phenotype database (dbFGP) reports a pathogenic variant c.947dupT in exon 6 that is probably associated with a classical phenotype of Fabry disease. In this case report, we report the case of a woman who is the sole family member with this type of pathogenic variant. Similar situations have not been described in the literature for this pathogenic variant, and it represents an important case of inter- and intrafamilial variability in patients with Fabry disease. The literature shows that de novo pathogenic variants are frequently found in the context of Fabry disease.
Genotype-by-socioeconomic status interaction influences heart disease risk scores and carotid artery thickness in Mexican Americans: the predominant role of education in comparison to household income and socioeconomic index
Authors: Diego Vincent P. , Manusov Eron G. , Mao Xi , Curran Joanne E. , Göring Harald , Almeida Marcio , Mahaney Michael C. , Peralta Juan M. , Blangero John , Williams-Blangero Sarah 
Published: September 2023

Background:Socioeconomic status (SES) is a potent environmental determinant of health. To our knowledge, no assessment of genotype-environment interaction has been conducted to consider the joint effects of socioeconomic status and genetics on risk for cardiovascular disease (CVD). We analyzed Mexican American Family Studies (MAFS) data to evaluate the hypothesis that genotype-by-environment interaction (GxE) is an important determinant of variation in CVD risk factors.Methods:We employed a linear mixed model to investigate GxE in Mexican American extended families. We studied two proxies for CVD [Pooled Cohort Equation Risk Scores/Framingham Risk Scores (FRS/PCRS) and carotid artery intima-media thickness (CA-IMT)] in relation to socioeconomic status as determined by Duncan’s Socioeconomic Index (SEI), years of education, and household income.Results:We calculated heritability for FRS/PCRS and carotid artery intima-media thickness. There was evidence of GxE due to additive genetic variance heterogeneity and genetic correlation for FRS, PCRS, and CA-IMT measures for education (environment) but not for household income or SEI.Conclusion:The genetic effects underlying CVD are dynamically modulated at the lower end of the SES spectrum. There is a significant change in the genetic architecture underlying the major components of CVD in response to changes in education.
The clinical characteristics of COVID-19 omicron variant infection in pregnant women and their neonates
Authors: Liu Li-Li , Lin Lv-Hua , Lin Fen , Yang Yi-Kang , Lin Chun-Fan , Zhang Lin , Huang Yu-Chan , Liao Yu-Wei , Zeng Yan-Qing , Zeng Guang-Kuan , Cao Yan-Bin , Zhu Rui-Zhen , Yang Li-Ye 
Published: September 2023

ObjectiveThe objective of this study was to analyze the clinical characteristics of pregnant women infected with the COVID-19 omicron variant and their neonates during the outbreak in Guangdong province, China.MethodsThe clinical data of pregnant women infected with the COVID-19 omicron variant and their neonates were retrospectively collected from two hospitals in Guangdong province. Information recorded included age of mother, date of birth, sex, weight at birth, mode of delivery, gestational age, feeding mode, Apgar score, signs, medical records, underlying comorbidities and laboratory results. The presence of SARS-CoV-2 viral RNA was tested using an real-time PCR assay.ResultsSeventy-nine pregnant women infected with COVID-19 omicron variant and their 68 neonates were included in this study. The vast majority (86.1%) of pregnant women was in their third trimester of pregnancy, and only 11 cases (15%) were in the first or second trimester. Of 79 pregnant women, 39 cases were asymptomatic at the time of infection, and 40 mothers presented with mild manifestations of COVID-19. The most common symptoms were fever (92.5%, 37/40) and cough (57.5%, 21/40). All of pregnant women did not receive chest computed tomography (CT) scan or X-ray. No pregnant woman developed severe pneumonia. A total of 68 neonates (3 set of twins) from 65 mothers with COVID-19 were reviewed. Among women who delivered, 34 cases underwent cesarean section, 31 cases underwent vaginal delivery. According to the timing of birth, there were 10 (14.7%) preterm neonates. Two babies were born dead (intrauterine fetal death after 22 weeks of gestation). Of the live babies born (66 cases) from mothers with COVID-19, 9 newborns were lower weight, and one preterm case was born with respiratory distress and intubated, he recovered and developed normally. SARS-CoV-2 nucleic acid testing was conducted on 41 neonates daily after birth, with only one neonate testing positive for SARS-CoV-2 infection on the third day after birth. The infected neonate exhibited typical fever and acute respiratory tract syndrome but ultimately had a good prognosis, recovering after 5 days of treatment.ConclusionAlthough preliminary data suggests the risk of severe maternal and fetal complications from Omicron variant infection during pregnancy is lower than previous variants and Delta variant. Our study, which was conducted on a limited population sample, indicates that there is a possibility of severe complications, such as stillbirth, occurring in some fetal cases. These findings emphasize the need for continued attention from obstetricians.