bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Cytotoxic Sesquiterpene Ester Derivatives from the Roots of Ferula mervynii
Authors: Yazici Bektas Nurdan , Altiparmak Ulbegi Gulsum , Aksoy Sagirli Pinar , Miski Mahmut 
Published: March 2023

AbstractThis study is the first chemical investigation of Ferula mervynii M. Sağıroğlu & H. Duman, an endemic species to Eastern Anatolia. The isolations of nine compounds including six previously undescribed sesquiterpene esters, 8‐trans‐cinnamoyltovarol (1), 8‐trans‐cinnamoylantakyatriol (3), 6‐acetyl‐8‐trans‐cinnamoyl‐3‐epi‐antakyatriol (5), 6‐acetyl‐8‐trans‐cinnamoylshiromodiol (6), 6‐acetyl‐8‐trans‐cinnamoylfermedurone (7), and 6‐acetyl‐8‐trans‐cinnamoyl‐(1S),2‐epoxyfermedurone (8), were described along with three known sesquiterpene esters, 6‐acetyl‐8‐benzoyltovarol (2), 6‐acetyl‐8‐trans‐cinnamoylantakyatriol (4), and ferutinin (9). The structures of novel compounds were elucidated through extensive spectroscopic analyses and quantum chemistry calculations. The putative biosynthetic pathways for compounds 7 and 8 were discussed. The extracts and isolated compounds were tested for cytotoxic activity against the COLO 205, K‐562, MCF‐7 cancer cell lines, and Human Umbilical Vein Endothelial Cell (HUVEC) lines using MTT assay. Compound 4 showed the highest activity against the MCF‐7 cell lines with an IC50 value of 16.74±0.21 μM.
Granulomatous mastitis in a male breast: A case report and review of literature
Authors: Kawashima Kei , Yamamoto Shinya , Narui Kazutaka , Fujiwara Yoshie , Adachi Shoko , Sasamoto Mahato , Oshi Masanori , Yamada Akimitsu , Kumagai Eita , Otani Masako , Endo Itaru 
Published: March 2023

AbstractGranulomatous mastitis (GM) is a rare disease, particularly among men. Herein, we present a case of GM diagnosed in a 63‐year‐old male patient who showed reduction in the tumor size during 3 months of observation.
Diagnosis of unicuspid aortic valve after loss of consciousness during cesarean section: A case report
Authors: Yukami Shun , Juri Takashi , Nakajima Asami , Daisuke Tachibana , Takahashi Yosuke , Iwata Shinichi , Yamamoto Akira , Mori Takashi 
Published: March 2023

AbstractLoss of consciousness is a rare but potentially serious complication of delivery by cesarean section under spinal anesthesia. Here, we report the case of a pregnant woman with unicuspid aortic valve that was incidentally diagnosed during aortic valve replacement after transient loss of consciousness during cesarean section.
Effect of Metal Layer Support Structures on the Catalytic Activity of NiFe(oxy)hydroxide (LDH) for the OER in Alkaline Media
Authors: Gort Christopher , Buchheister Paul W. , Klingenhof Malte , Paul Stephen D. , Dionigi Fabio , van de Krol Roel , Kramm Ulrike I. , Jaegermann Wolfram , Hofmann Jan P. , Strasser Peter , Kaiser Bernhard 
Published: March 2023

AbstractPhotoelectrochemical (PEC) cells promise to combine the benefits of photovoltaics and electrolysis in one device. They consist of a photoabsorber functionalized with an electrocatalyst to harvest faradaic currents under reduced overpotentials. To protect the absorber from the harsh reaction conditions, a protective buffer layer (e. g. TiO2) is added between absorber and catalyst. In this work, we investigate the influence of the catalyst support systems Ti/TiOx and Ti/TiOx/M (M=Au, Ni, Fe) on the overall activity and stability of nickel and iron mixed layered double hydroxides for the alkaline oxygen evolution reaction (OER). The catalyst performance on the bare Ti/TiOx substrate is very poor, but the incorporation of a metallic interlayer leads to two orders of magnitude higher OER current densities. While a similar effect has been observed for M=gold supported systems, we show that the same effect can be achieved with M=nickel/iron, already contained in the catalyst. This proprietary metal interlayer promises a cheap OER performance increase for PEC cells protected with titania buffer layers. Detailed XPS show an improved transformation of the starting catalyst material into the highly active (oxy)hydroxide phase, when using metallic interlayers. From these experiments a pure conductivity enhancement was excluded as possible explanation, but instead an additional change in the local atomic and electronic structure at the metal‐support and metal‐catalyst interfaces is proposed.
Fine Tuning of Quantum Dots Photocatalysts for the Synthesis of Tropane Alkaloid Skeletons**
Authors: Dabbous Ali , Colson Eloïse , Chakravorty Debargha , Mouesca Jean‐Marie , Lombard Christian , Caillat Sylvain , Ravanat Jean‐Luc , Dubois Fabien , Dénès Fabrice , Renaud Philippe , Maurel Vincent 
Published: March 2023

AbstractSeveral types of Quantum Dots (QDs) (CdS, CdSe and InP, as well as core‐shell QDs such as type I InP‐ZnS, quasi type‐II CdSe‐CdS and inverted type‐I CdS‐CdSe) were considered for generating α‐aminoalkyl free radicals. The feasibility of the oxidation of the N‐aryl amines and the generation of the desired radical was evidenced experimentally by quenching of the photoluminescence of the QDs and by testing a vinylation reaction using an alkenylsulfone radical trap. The QDs were tested in a radical [3+3]‐annulation reaction giving access to tropane skeletons and that requires the completion of two consecutive catalytic cycles. Several QDs such as CdS core, CdSe core and inverted type I CdS‐CdSe core‐shell proved to be efficient photocatalysts for this reaction. Interestingly, the addition of a second shorter chain ligand to the QDs appeared to be essential to complete the second catalytic cycle and to obtain the desired bicyclic tropane derivatives. Finally, the scope of the [3+3]‐annulation reaction was explored for the best performing QDs and isolated yields that compare well with classical iridium photocatalysis were obtained.
High‐Entropy Solid‐State Na‐Ion Conductor for Stable Sodium‐Metal Batteries
Authors: Sun Ge , Lin Hezhe , Yao Shiyu , Wei Zhixuan , Chen Nan , Chen Gang , Zhao Huichao , Du Fei 
Published: March 2023

AbstractSolid‐state sodium‐metal batteries (SSBs) hold great promise for their merits in low‐cost, high energy density, and safety. However, developing solid electrolyte (SE) materials for SSBs with high performance is still a great challenge. In this study, high‐entropy Na4.9Sm0.3Y0.2Gd0.2La0.1Al0.1Zr0.1Si4O12 was synthesized at comparatively low sintering temperature of 950 °C with high room‐temperature ionic conductivity of 6.7×10−4 S cm−1 and a low activation energy of 0.22 eV. More importantly, the Na symmetric cells using high‐entropy SE show a high critical current density of 0.6 mA cm−2, outstanding rate performance with fairly flat potential profiles at 0.5 mA cm−2 and steady cycling over 700 h under 0.1 mA cm−2. Solid‐state Na3V2(PO4)3||high‐entropy SE||Na batteries are further assembled manifesting a desirable cycling stability with almost no capacity decay after 600 cycles and high Columbic efficiency over 99.9 %. The findings present opportunities for the design of high‐entropy Na‐ion conductors toward the development of SSBs.
A review of radiological definitions of sarcopenia in cancer
Authors: Wang James W. , Chen Jiarong , McGregor Alison H. , Williams Matthew 
Published: March 2023

AbstractBackgroundSarcopenia in cancer impacts overall survival, surgical complications, and side effects of oncological treatments. Cancer patients frequently receive cross‐sectional imaging, allowing incidental capture of radiological sarcopenia biomarkers. These biomarkers vary by imaging modality, tumour group, patient demographics, and anatomy but lack a consensus with regard to clinical application. In this article, we provide an overview of radiology‐based sarcopenia biomarkers by anatomy and their prevalence in the literature.MethodsIn accordance with previously published scoping review protocol, we searched PubMed/MEDLINE, Embase, Scopus, and Cochrane between 2007 and June 2021. Studies were independently reviewed by two authors with Cohen's kappa 0.81 and reported using descriptive statistics.ResultsThere were 5649 titles and abstracts reviewed, including 459 full‐text articles. There were 23 additions found through references, resulting in 482 total studies. There is a consistent year‐on‐year increase of new radiological sarcopenia landmarks since 2015, with 49.8% studies reporting novel definitions of sarcopenia. The majority of studies ranged between 50 and 300 participants and featured an abdominal sarcopenia marker (94.4%), of which 75.2% used the skeletal muscle index at L3 (L3SMI). Sarcopenia prevalence ranged from 8.33% to 89.66%. Biomarkers are often applied across genders and ethnicities, regardless of the original population the definition originated from, despite the emergence and availability of ethnic‐specific alternatives.ConclusionThere remains a need to incorporate demographics and age into predictive models derived from sarcopenia biomarkers obtained through routine clinical imaging. Use of individual biomarkers needs to be made with careful consideration of the population in which the biomarkers were generated.
Board gender diversity and firm performance: The mediating role of sustainability disclosure
Authors: Alodat Ahmad Yuosef , Salleh Zalailah , Nobanee Haitham , Hashim Hafiza Aishah 
Published: March 2023

AbstractThis study aims to investigate the mediating role of sustainability disclosure in the relationship between board gender diversity and performance of the firm in the non‐financial listed on Amman Stock Exchange (ASE). Using data from Jordan listed firms in ASE for the period of 2014–2018, the direct effect between board gender diversity on firm performance was examined, and the indirect effect of the mediating role of sustainability disclosure was also tested. The findings showed that board gender diversity has a positive and significant effect on performance of the firm. Furthermore, the results showed that sustainability disclosure fully mediates the relationship between board gender diversity and the performance of the firm. This study contributes to the knowledge by examining the mediating role of the sustainability disclosure on the relationship between board diversity and firm performance. Integrating knowledge of gender, corporate governance and sustainability enrich the study of firm performance. Regulators, investors and managers should consider not only gender diversity as a key enabler of growth but also sustainability disclosure. By increasing the level of sustainability disclosure and having a sound governance system may improve firm performance which in turn attracts investors because sophisticated investors nowadays embed sustainability consideration into their strategies to generate positive outcomes. In addition, this study provides evidence on sustainability disclosure as a mediating variable on the relationship between board gender diversity and performance of the firm in the ASE which is one of the emerging markets.
The potential for synthesized invasive plant biochar with hydroxyapatite to mitigate allelopathy of Solidagocanadensis
Authors: Xu Wenna , Huang Xueyi , Yuan Jiajie , Wang Yanhong , Wu Mengmin , Ni Hongtai , Dong Lijia 
Published: March 2023

AbstractFew studies tried to explore the mitigation effect and underlying mechanisms of biochar and their complex for negative allelopathy from invasive plants, which may provide a new way in the invasive plant management. Herein, an invasive plant (Solidago canadensis)‐derived biochar (IBC) and its composite with hydroxyapatite (HAP/IBC) were synthesized by high temperature pyrolysis, and characterized by scanning electron microscopy, energy dispersion spectrometer, X‐ray diffraction, Fourier transform infrared spectroscopy, and X‐ray photoelectron spectroscopy. Then, both the batch adsorption and pot experiments were conducted to compare the removal effects of kaempferol‐3‐O‐β‐D‐glucoside (C21H20O11, kaempf), an allelochemical from S. canadensis, on IBC and HAP/IBC, respectively. HAP/IBC showed a stronger affinity for kaempf than IBC due to its higher specific surface area, more functional groups (P‐O, P‐O‐P, PO43−), stronger crystallization [Ca3(PO4)2]. The maximum kaempf adsorption capacity on HAP/IBC was six times higher than on IBC (10.482 mg/g > 1.709 mg/g) via π–π interactions, functional groups, and metal complexation. The kaempf adsorption process could be fitted best by both pseudo‐second‐order kinetic and Langmuir isotherm models. Furthermore, HAP/IBC addition into soils could enhance and even recover the germination rate and/or seedling growth of tomato inhibited by negative allelopathy from the invasive S. canadensis. These results indicate that the composite of HAP/IBC could more effectively mitigate the allelopathy from S. canadensis than IBC, which may be a potential efficient approach to control the invasive plant and improve invaded soils.
Electrochemical Borylation of Electron‐Deficient Alkenes and Allenoates
Authors: Aelterman Maude , Jubault Philippe , Poisson Thomas 
Published: March 2023

AbstractThe electrochemical borylation of electro‐deficient alkenes and allenoates is disclosed. In an undivided cell and under galvanostatic conditions a panel of Michael acceptor and allenoates was readily reacted. The reaction offered an access to versatile borylated building blocks in good to excellent yields (20 examples, 47 % to 91 % yields). A plausible reaction mechanism, based on the literature precedent was suggested.
Electrochemical sensing of bisphenol A on single‐walled carbon nanotube paper electrodes
Authors: Bui Catalina , La Flower Gavin , Paudyal Janak 
Published: March 2023

AbstractThe electrochemical detection of BPA often requires modification of electrodes to overcome BPA′s slower kinetics and higher oxidation potential. This work reports a modification‐free, paper electrode based on vacuum‐filtered SWCNT thin film. The prepared electrode does not need to be polished or transferred into the conducting substrates. The linear sweep voltammetric detection showed a linear response from 0.5–10 μM and 25–100 μM with the experimental LOD of 1.0 μM (S/N=3). The interference study and good recovery percentage (93–105 %) in real water samples demonstrated the method‘s selectivity. The sensor can be promising for developing a simple, low‐cost, portable, and paper‐based BPA monitoring system.
Green Sea Turtles (Chelonia mydas) Accumulate Heavy Metals Near a Former Skeet Shooting Range in Kailua, O'ahu, Hawai'i
Authors: Shaw Katherine R. , Balazs George H. , Jones T. Todd , Lynch Harry W. , Liu Jing , Cobb George P. , Klein David M. , Lynch Jennifer M. 
Published: March 2023

Abstract
The present study determined if green sea turtles (Chelonia mydas) in Kailua Bay, Oahu, in the Hawaiian Islands have elevated blood and scute lead (Pb), arsenic (As), and antimony (Sb) concentrations resulting from lead deposition at a historic skeet shooting range. Blood and scute samples were collected and analyzed for Pb, As, and Sb via inductively coupled plasma-mass spectrometry. Prey, water, and sediment samples were also analyzed. Turtle samples in Kailua Bay (45) have blood Pb concentrations (328 ± 195 ng/g) greater than a reference population (Howick Group of Islands, 29.2 ± 17.1 ng/g). Compared with other green turtle populations, only turtles in Oman, Brazil, and San Diego, CA have blood Pb concentrations greater than turtles in Kailua Bay. The estimated daily exposure of Pb from algae sources in Kailua Bay (0.12 mg/kg/day) was significantly lower than the no observed adverse effect level (100 mg/kg) of red-eared slider turtles. However, the chronic effects of Pb on sea turtles is poorly understood and continued monitoring of this population will increase our understanding of the Pb and As loads of sea turtles in Kailua Bay. Environ Toxicol Chem 2023;42:1109–1123. © 2023 SETAC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.
Abstract
An estimated 500 000 pounds of lead (Pb) shot was deposited in the sand and surrounding waters by the Honolulu Skeet Club between 1933 and 1956 (Board of Land and Natural Resources, 2012). This has caused an increase in sediment, algae, and sea turtle blood and scute Pb concentrations in Kailua Bay, Hawaii.
Bayesian quickest detection‐based spectrum sensing for cognitive UAV networks
Authors: Wu Jun , Wang Cong , Liang Haoyu 
Published: March 2023

AbstractWith the gradual popularization of unmanned aerial vehicles (UAVs), spectrum resources are increasingly scarce. At this time, cognitive radio (CR) technology came into being, which can provide available spectrum resources for UAVs. However, different from the conventional CR networks, the UAV's location flexibility significantly reduces the spectrum sensing performance and increases the detection delay. Therefore, we propose a Bayesian quickest detection‐based spectrum sensing for cognitive UAV networks in this paper. To this aim, we establish a multislot spectrum sensing model in a cognitive UAV network to realize cooperative spectrum sensing (CSS) within the single UAV and avoid disadvantages of cooperation among multiple UAVs. On the basis of this, we make use of Bayesian quickest detection to implement multislot spectrum sensing and evaluate its false alarm probability and detection delay. Further, the tradeoff problem between the false alarm and the detection delay is developed and converted into an optimization stopping time problem. Subsequently, the stopping time problem is theoretically proved and solved. Finally, compared to Bayesian detection, numerical simulation results show that the superiority of Bayesian quickest detection with respect to the false alarm probability and the detection delay is evident, which proves the correctness and effectiveness of the proposed tradeoff problem.
Flavour them up! Exploring the challenges of flavoured plant‐based foods
Authors: Pérez Cristina Barallat , Oliviero Teresa , Fogliano Vincenzo , Janssen Hans‐Gerd , Martins Sara I. F. S. 
Published: March 2023

AbstractFood flavourings are often added to enhance overall flavour experience during food consumption and their use in plant‐based food analogues is crucial. The flavour sensory perception is strongly mediated by flavour–food matrix interactions. Aroma molecules establish chemical and physical bonds with lipids and carbohydrates, but proteins play a pivotal role having a strong flavour binding minimizing aroma release and quenching flavour perception. Consequently, final food quality is reduced and so is consumer acceptance. Depending on the chemical structure of the flavour and the type of protein involved, the strength of the flavour–protein binding can vary. It is of great importance to understand if this interaction remains under dynamic conditions such as the oral processing during food consumption. This review aims to gain insights into the influence of the chemical structure and physicochemical features of both proteins and flavours on the binding mechanism. Moreover, the potentiality of coupling in vivo instrumental analysis with sensory methods to study flavour release in real time is explored. Elucidating the drivers of flavour interaction with, and release from, the food matrix is essential to develop flavour solutions for the new generation of plant‐based food products.
The effect of “failed” community mental health centers on non‐white mortality
Authors: Avery Mallory , LaVoice Jessica 
Published: March 2023

AbstractThe Community Mental Health Act of 1963 established Community Mental Health Centers (CMHCs) across the country with the goal of providing continuous, comprehensive, community‐oriented care to people suffering from mental illness. Despite this program being considered a failure by most contemporary accounts, the World Health Organization advocates for a transition from the institutionalization of the mentally ill to a system of community‐centered care. In this paper, we construct a novel dataset documenting the rollout of CMHCs from 1971 to 1981 to identify the effect of establishing a CMHC on county level mortality rates, focusing on causes of death related to mental illness. Though we find little evidence that access to a CMHC impacted mortality rates in the white population, we find large and robust effects for the non‐white population, with CMHCs reducing suicide and homicide rates by 8% and 14%, respectively. CMHCs also reduced deaths from alcohol in the female non‐white population by 18%. These results suggest the historical narrative surrounding the failure of this program does not represent the non‐white experience and that community care can be effective at reducing mental health related mortality in populations with the least access to alternative treatment options.
Impact of access to treatment on patient‐reported outcomes among rheumatoid arthritis patients with tDMARDs and bDMARDS in two Latin‐American countries: A prospective observational study
Authors: Reyes Juan M. , Gutierrez‐Ardila Magda V. , Madariaga Hugo , Otero William , Guzman Renato , Izquierdo Jorge , Del Castillo David J. , Abello Mauricio , Velez Patricia , Ponce de Leon Dario , Lukic Tatjana , Amador Luisa F. , Castaño Natalia 
Published: March 2023

AbstractBackground and AimsA noninterventional prospective study was performed in Colombia and Peru. The aim was to describe the impact of access to treatment on Patient‐reported outcomes (PRO) in patients with Rheumatoid arthritis (RA) after failure to conventional disease‐modifying antirheumatic drugs (DMARDs) in real‐life conditions.MethodsThe impact of access to treatment was measured by access barriers, time to supply (TtS) and interruption evaluating their effect in changes of PROs between baseline and 6‐month follow‐up between February 2017 and November 2019. The association of access to care with disease activity, functional status, health‐related quality of life was assessed using bivariate and multivariable analysis. Results are expressed in least mean difference; TtS in mean number of days for delivery of treatment at baseline. Variability measures were standard deviation and standard error.ResultsOne hundred seventy patients were recruited, 70 treated with tofacitinib and 100 with biological DMARDs. Thirty‐nine patients reported access barriers. The mean of TtS was 23 ± 38.83 days. The difference from baseline to 6‐month visit in PROs were affected by access barriers and interruptions. There was not statistically significant difference in the of PRO's score among visits in patients that reported delay of supply of more than 23 days compared to patients with less days of delay.ConclusionThis study suggested the access to treatment can affect the response to the treatment at 6 months of follow‐up. There seems to be no effect in the PROs for delay of TtS during the studied period.