bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avifaunal Diversity of Northwestern Himalayas (Jammu &amp; Kashmir) and Trans Himalayas (Ladakh)
Authors: Yousuf Parvaiz , Parvaiz Semran , Zehbi Nisheet , Zargar Bilal Nasir , Rather Rouf , Tantray Javeed Ahmad , Lateef Mohammad 
Published: February 2023

Abstract
The Himalayas are home to a wide variety of animals and plants, making it one of the world's most biodiverse regions. Both the northwestern Himalayan region of Jammu & Kashmir and the trans-Himalayan region of Ladakh are home to a wide variety of bird species because of varied topography and temperature. In this study, we collected the field data and checklists over a period of 3 years based on the compilation of data from published & unpublished scientific literature, print & electronic, currently accessible in the form of research articles, papers, books, websites, web pages, & field notes. The Northwestern Himalayas (Jammu and Kashmir) and trans-Himalayas (Ladakh) are home to 677 bird species belonging to 89 families (out of 107 families in the Indian sub-continent), which is equal to 6.77% of total bird species (>10000) found globally and 49.2% of total bird species (1376) found in the Indian subcontinent. The family Muscicapidae (53, 7.8%) has the most species, followed by Accipitridae (41, 6%), and so on. Moreover, the number of threatened species is 54 (8%), which includes 22 (3.25%), 23 (3.40%), 6 (0.8%) & 3 (0.44%) under Near Threatened, Vulnerable, Endangered, & Critically Endangered categories. Among 677 species, 228 species (33.77%) are found in all the 3 regions, 77 (11.4%) in only Jammu & Kashmir but not Ladakh, 24 (3.55%) in Jammu & Ladakh but not in Kashmir, 80 (11.85%) in Kashmir & Ladakh but not in Jammu, 152 (22.5%) only in Jammu but not in Kashmir & Ladakh, 26 (3.84%) only in Kashmir but not in Jammu & Ladakh, 71 (10.51%) only in Ladakh but not in Jammu & Kashmir. This provides the first-of-its-kind comprehensive data on bird diversity in these regions.
Analysis of People’s Opinions Based on the Vaccination Procedure and E-Commerce Product Reviews using XLNET Framework
Authors: patidar Mrs RITU PATIDAR , PATEL SACHIN PATEL 
Published: February 2023

Abstract
Many people have been severely affected by the COVID-19 outbreak, which has left them anxious, terrified, and other difficult feelings. Since the introduction of coronavirus vaccinations, people’s emotional spectrum has broadened and become more sophisticated. We want to perceive and interpret their sentiments using deep learning techniques in this work. The most efficient way to convey one’s thoughts and feelings right now is via social media, and using Twitter may help one have a better knowledge of what is popular and what is going through other people’s minds.Analysing and visualisation of data plays a vital role in Data Science; as customers over e-commerce increase, feedback/reviews shared by them increase significantly, and decisions by a new customer to buy a product or not rely on these reviews; reviews might falsely be displayed which may be involving in controlling if any products demand and supply so, reviews analysing and visualisationto understand their genuinely play an important role over e-commerce nowadays. Our primary objective in conducting this study was to understand better the various perspectives held by individuals on the process of vaccination and reviews of products purchased online.The proposed work displayed the way to analyses and visualisation methodologies which give quick and faster grasping of the e-commerce data even with high dimensions, which gives a quicker conceptual understanding of the data.The proposed data was analysed based on various parameters, which gives a wholesome overview of the data, and the relationship of data with various other parameters; all correlation and non-correlation variables were mapped and analysed.The proposed work gives an idea about observations in sentiments over different arguments and which sentiments are related to each parameter; it creates the scope for modelling to extract some decision-making insights from the data to make application areas such as product quality and customer satisfaction efficient based on the results of modelling.
Bacteroides rhinocerotis sp. nov., isolated from the fresh feces of rhinoceros in Beijing Zoo
Authors: Li Xue , Sun Peilin , Gong Liang , Shi Weixiong , Xiang ZhiGuang , Li Ming , Su Lei , Qin Chuan 
Published: February 2023

Abstract
A Gram˗stain˗negative, anaerobic, non˗motile, non˗spore˗forming, rod˗shaped bacterial strain named as NGMCC 1.200684T was isolated from the fresh feces of rhinoceros in Beijing Zoo. Based on 16S rRNA gene sequences, phylogenetic analysis indicated that strain NGMCC 1.200684T belonged to the genus Bacteroides and was most strongly related to the type strain of Bacteroides uniformis ATCC 8492T (96.88%). The G+C content of the genomic DNA was determined to be 46.62 mol%. Between strains NGMCC 1.200684T and Bacteroides uniformis ATCC 8492T, the average nucleotide identity (ANI) and digital DNA˗DNA hybridization (dDDH) were 93.89 and 67.60%, respectively. Strain NGMCC 1.200684T can produce acid from fermentation of several substrates, including glucose, mannitol, lactose, saccharose, maltose, salicin, xylose, cellobiose, mannose, raffinose, sorbitol, trehalose, D˗galactose，maltotriose. The major cellular fatty acids (>10 %) were identified as anteiso˗C15:0, iso˗C15:0, iso˗C14:0, iso˗C17:0 3˗OH. The polar lipid profile of strain NGMCC 1.200684T was determined to contain diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, three unknown phospholipids, two unknown aminophospholipids. Based on phenotypic, phylogenetic and chemotaxonomic characteristics, a novel species of the genus Bacteroides, Bacteroides rhinocerotis sp. nov. is proposed. The type strain is NGMCC 1.200684T (=CGMCC 1.18013T=JCM 35702T).
Ionic Liquid Coating-Driven Nanoparticle Delivery to the Brain: Applications for NeuroHIV
Authors: Hamadani Christine M. , Mahdi Fakhri , Merrell Anya , Flanders Jack , Cao Ruofan , Vashisth Priyavrat , Pride Mercedes C. , Hunter Alysha N. , Singh Gagandeep , Roman Gregg , Paris Jason J. , Tanner Eden E. L. 
Published: February 2023

Abstract

Delivering cargo to the central nervous system (CNS) remains a pharmacological challenge. For infectious diseases such as HIV, the CNS acts as a latent reservoir that is inadequately managed by systemic antiretrovirals (ARTs). ARTs thus cannot eradicate HIV, and given CNS infection, patients experience an array of neurological deficits that are collectively referred to as ‘neuroHIV’. Herein we report the development of bioinspired ionic liquid-coated nanoparticles (IL-NPs) for in situ hitchhiking on red blood cells (RBCs), which enabled 48% delivery of intravenously infused cargo to the brain. Moreover, the ionic liquid (IL) choline trans-2-hexenoate (CA2HA 1:2) demonstrated preferential accumulation in parenchymal microglia over endothelial cells post-delivery. We further demonstrate the successful loading of abacavir (ABC), an ART that is challenging to encapsulate, into the IL-coated NPs and verify the retention of antiviral efficacy in vitro. IL-NPs were not cytotoxic to primary human peripheral blood mononuclear cells (PBMCs) and the CA2HA 1:2 coating conferred notable anti-viremic capacity on its own. In addition, in vitro cell culture assays showed markedly increased uptake of IL-coated nanoparticles into neuronal cells compared to bare nanoparticles. This work debuts bioinspired ionic liquids as promising nanoparticle coatings to assist CNS biodistribution and has the potential to revolutionize the delivery of cargos (i.e., drugs, viral vectors) through compartmental barriers such as the blood-brain-barrier (BBB), illustrated in the graphical abstract below.
Engineering a HER2-CAR-NK cell secreting soluble programmed cell death protein with superior anti- tumor efficacy
Authors: Xia Wenjiao , Chen Jiaxin , Hou Wenqing , Chen Junshen , Xiong Ying , Li Hongyan , Qi Xin , Xu Hui , Xie Zhuoquan , Li Mingfeng , Zhang Xiaomin , Li Jing 
Published: February 2023

Abstract
To improve the therapeutic efficacy to relapse patient based-trastuzumab therapy, new therapy strategy was urgent to be explored. It is well known that HER2-specific chimeric antigen receptor (CAR) expressing NK cells is rapid development for solid tumor therapy with many advantages over HER2-CAR-T, and as an endogenous molecule, soluble PD-1 (sPD-1), a PD-1 extracellular domain, can block PD-1/PD-L1 pathway to promote cancer immunology. Herein, we engineered a new HER2-CAR-NK cells with co-expression of sPD-1 (sPD-1-CAR-NK cells), and assessed the cytotoxicity toward cancer cells, immunity activations and sPD-1 releases of sPD-1-CAR-NK cells in vitro and in both immunocompetent mouse model and humanized mouse model bearing HER2-high expression or trastuzumab-resistance-HER2 breast cancer. Furthermore, we compared with the anti-tumor effects of sPD-1-CAR-NK cells, HER2-CAR-NK cells and HER2-CAR-NK cells in combination with sPD-1. We demonstrated that HER2-CAR-NK cells specially diminished various HER2-expression breast cancer cells, and sPD-1-CAR-NK cells had ability to release bioactive sPD-1 and promote cytolysis activities of HER2-CAR-NK cells when incubated with target cells including trastuzumab-resistant cells. In vivo, sPD-1-CAR-NK cells had superior immunological anticancer efficacy than HER2-CAR-NK cells, and advantage over HER2-CAR-NK cells along with endogenous sPD-1. Together, these data indicate that HER2-specific CAR-NK cells carrying sPD1 show promise as a treatment for patients with HER2-positive breast cancer, and are is beneficial to develop for trastuzumab-resistance patient.
Prevalence of risk factors for human immunodeficiency virus among sexually active women in Rwanda: a nationwide survey
Authors: Nuwabaine Lilian , Kawuki Joseph , Namulema Angella , Asiimwe John Baptsist , Sserwanja Quraish , Donkar Elorm , Gatasi Ghislaine 
Published: February 2023

Abstract
Background
The Human Immunodeficiency Virus (HIV) remains a global health burden and despite the advancements in antiretroviral therapy and various strategies employed to curb HIV infections, the incidence of HIV remains disproportionately high among women. Therefore, this study aimed to determine the prevalence of the risk factors for acquisition of HIV among sexually active women in Rwanda.
Methods
Secondary data from the 2020 Rwanda Demographic Health Survey comprising 10,684 sexually active women was used. Multistage stratified sampling was employed to select the study participants. Multivariable logistic regression was conducted to determine the associated risk factors, using the SPSS (version 25).
Results
Of the 10,684 sexually active women, 28.7% (95% Confidence Interval (CI): 27.5–29.4) had at least one risk factor for HIV acquisition. Having no education (AOR = 3.65, 95%CI: 2.16–6.16), being unmarried (AOR = 4.50, 95%CI: 2.47–8.21), being from female-headed households (AOR = 1.75, 95%CI: 1.42–2.15), Protestant (AOR = 1.28, 95%CI: 1.09–1.50) and other religions (AOR = 1.99, 95%CI: 1.41–2.80), not having health insurance (AOR = 1.34, 95%CI: 1.09–1.65), no HIV test history (AOR = 1.44, 95%CI: 1.01–2.08), being from the poorest wealth quintile (AOR = 1.61, 95%CI: 1.14–2.27) and lack of exposure to mass media (AOR = 1.30, 95%CI: 1.07–1.58) were associated with higher odds of risk factors for HIV acquisition. In contrast, age groups of 25–34 (AOR = 0.56, 95%CI: 0.44–0.71) and 35–44 (AOR = 0.62, 95%CI: 0.48–0.80) years, rural residence (AOR = 0.63, 95%CI: 0.49–0.81) and being from western region (AOR = 0.67, 95%CI: 0.48–0.94) were associated with less odds of risk factors for HIV acquisition.
Conclusion
More than a quarter of sexually active women in Rwanda had exposure to at least one risk factor for HIV acquisition. There is a need to maximize the use of mass media in disseminating HIV prevention and behavioral change messages. Engagement of religious leaders and promotion of HIV testing, especially among the never-testers would also be vital strategies in successful HIV prevention programs.
Mangrove mudwhelk (Terebralia palustris, Linnaeus, 1767) harvesting and subsequent use in basket trap fishery, at the Mida creek Biosphere reserve, Kenya
Authors: Nthiga Aniel , Kihia Charles , Muthumbi Agnes , Okondo Julius , Njuguna Vincent 
Published: February 2023

Abstract

Traditionally basket traps, baited with gastropods, seagrass, among others, deployed in nearshore fishery, are typical to tropical coastlines. Although fish landings from such fishery are documented, bait utilized remains sketchy. The Indo-Pacific Mangrove mudwhelk (Terebralia palustris) are keystone species, threatened by habitat degradation but also the poorly documented human harvesting. Forest bait harvesting is comparable to tropical forest hunting but has received scant attention in spite of potential impacts. This study elucidates mudwhelk baited trap harvest and subsequent use in basket trap fishery at the Mida creek. Bait and fish landings and effort, and habitat attributes at sites at the Mida creek, are determined and variations described. Results show 0.64 kg.m-2 of mudwhelk occur at Mida creek, with higher biomass (P<0.05) at the more complex Dabaso forest. Harvesters targeted larger individuals (10.38 cm), extracting 9.26 kg.harvest-1 at a rate of 0.12 kg.min-1, with higher harvest (P<0.001), at the less complex Kirepwe forest. The mudwhelk bait, were used to land 0.69 kg.fisher-1 of fish with relatively low landing efficiency (>1.0 kg fish.kg-1 bait), but higher (P<0.001) landings at Kirepwe. We tentatively estimate Mida creek mudwhelk harvest of 5.9 t.yr-1, corresponding to 5.2% of stock (115.2 t), but may mask localized overharvesting at sites with higher trap fishery participation and require more testing to guide sustainable management.
Taxing in a Pandemic: An Assessment of the Impact of Covid-19 Pandemic on Tax Revenues and Revenues of Small and Medium Enterprises in Ghana
Authors: Ntiamoah Jones Adjei , Asare Joseph , Arhenful Peter , Owusu-Akomeah Michael Nana 
Published: February 2023

Abstract

This study assessed the impacts of the COVID-19 pandemic on tax revenues and small and medium enterprises (SMEs) revenues in Ghana using qualitative and quantitative analysis. These impacts were analyzed using autoregressive tax regressions, buoyancy, and tax elasticity formulas. A simple radon sampling was used to select 350 SMEs in five major cities in Ghana. The findings point to "Demand" as a critical factor influencing SMEs sales and revenue with a rating of 5.3, a p-value less than the significance level of 0.05, and a deviation of 0.864, indicating the extent of the impact on tax revenue and sales of small and medium enterprises during a pandemic. In addition, a coefficient based on the ORL model application shows a value of 0.9565 in support of the econometric model used. The study also finds that tax revenue could drop by 8%, and VAT revenue could drop by 1% or more. A tax buoyancy of 0.1% or 100% in forecasting tax revenue could be observed depending on the severity and impact of the pandemic. The findings show that tax revenue in a pandemic is impacted adversely, which requires logical and coordinated approaches to improve tax compliance.
Knowledge and awareness of Neglected Tropical Diseases among senior medical students and intern doctors in Bangladesh
Authors: Rahman Md. Sahidur , Susan Farha , Mawa Kashfia , Islam Sabrina 
Published: February 2023

Abstract
Proper knowledge and awareness of healthcare professionals are imperative for the control and eradication of Neglected tropical diseases (NTDs). The study aimed to measure the level of knowledge and awareness of medical students and intern doctors in Bangladesh to facilitate control strategies. Data were collected through an online questionnaire and ranked the participants by scoring their responses as one for correct and zero for wrong answers. Later, the rank of respondents was analyzed with the socio-demographic characteristics using the Chi-square and Fisher exact probability tests. Of the total 31.4%, (32.2% students and 29.8% interns) participants achieved a good score while 24.6% (24.5% students and 24.8% intern doctors) demonstrated poor rank. The geographical location of participants and previous experience of seeing any NTD patients were significantly associated (P = 0.001) with the level of knowledge and awareness. Most of them (76.4%) acknowledged participating in control activities of NTDs in Bangladesh and marked highly the importance of mass awareness (83.8%) and easy diagnostic facilities (71.2%). We advocate focusing on NTDs in the medical education curriculum and professional training especially on the common NTDs of Bangladesh to confirm the active involvement of these primary stakeholders in prevention and control programs.
The Rule of Law in the ESG Framework in the World Economy
Authors: Leogrande Angelo 
Published: February 2023

Abstract
In this article, I have estimated the Rule of Law for 193 countries using data from the Environment Social and Governance-ESG database of World Bank. I have used different econometric techniques to estimate the value of “Rule of Law” i.e.: Panel Data with Fixed Effects, Panel Data with Random Effects, Pooled OLS. I found that Rule of Law is positively associated, among others to “Regulatory Quality” and “Control of Corruption” and negatively associated among others to, “Access to Electricity” and “Prevalence of Overweight”. I have performed a cluster analysis with the k-Mean algorithm optimized with the Elbow Method and I find the presence of four clusters. Finally, I present a confrontation among eight different machine-learning algorithms to predict the level of Rule of Law. I find that Linear Regression is the best predictor according to MAE, MSE, RMSE and R-squared.
JEL CODE: D7, D70, D72, D73, D78.
Comparison of Long-Term Outcomes of Infliximab and Adalimumab Therapy in Biologic-Naive Patients with Ulcerative Colitis
Authors: Durak Muhammed Bahaddin , Şimşek Cem , Yüksel İlhami 
Published: February 2023

Abstract
Background
Data comparing their long-term efficacy and safety of Infliximab (IFX) and adalimumab (ADA) in moderate to severe ulcerative colitis (UC) is limited. In this study we aimed to compare the long-term effectiveness and safety of IFX and ADA in UC who had not previously received biologic therapy.
Methods:
Data from patients treated between 2007 and 2021 was collected and analyzed. Outcomes evaluated included UC-related hospitalization, colectomy, steroid use, and serious infections leading to treatment cessation.
Results
Of 86 UC patients, 41 received IFX and 45 received ADA. No differences were found in terms of demographics, risk factors, baseline Mayo scores and treatment history. During anti-TNF therapy, steroid use was significantly higher in the ADA group (44.4%) compared to the IFX group (14.6%). UC-related hospitalization and colectomy rates were similar between the two groups, as were rates of serious infection leading to treatment cessation. These outcomes were similar in UC patients treated with IFX or ADA monotherapy or in combination with an immunomodulator. The Kaplan-Meier analysis showed that the duration of discontinuation of the drug due to secondary loss of response was longer in the IFX group compared ADA the other group, although the difference was not statistically significant (72.5% versus 46.7%, p = 0.057).
Conclusion
Overall, the study suggests that IFX and ADA may be similar in terms of clinical outcomes for UC patients who are new users of anti-TNF agents, but the higher rate of steroid use in the ADA group should be noted.
CoolMOS based high-voltage power supply with PRF up to 200 kHz for metal vapor active media excitation
Authors: Trigub Maxim , Gembukh Pavel , Semenov Konstantin 
Published: February 2023

Abstract
The paper presents the development and investigation of the semiconductor power supply for metal atoms active media excitation with pulse repetition rate up to 200 kHz. The high voltage pulse formation is based on the LTD-generator concept (linear transform driver) with single turn step-up transformer. This PRF equalled 200 kHz when the consumption power was 750 W. The record pulse repetition frequency (PRF) of CuBr active medium excited by semiconductor excitation source was achieved. The mean radiation power was equal to 650 mW under excitation condition: PRF was to 150 kHz and pulse energy input was 160 µJ/cm3.
Allocation concealment appraisal of clinical therapy trials using the extended Composite Quality Score (CQS-2) – An empirically based update (Preprint)
Authors: Mickenautsch Steffen , Yengopal Veerasamy 
Published: February 2023

Abstract
Objectives
To revise CQS-2/Criterion II concerning allocation concealment appraisal for prospective, controlled clinical therapy trials.
Methods
Meta-analyses of trials with inadequate allocation concealment were tested for in-between trial heterogeneity (I2 > 0) due to imbalances in baseline variables. Meta-analyses with positive test results were used as a basis to deduce criteria for adequate allocation concealment. The CQS-2/Criterion II was reformulated in line with the findings.
Result
One suitable meta-analysis was identified. Two forest plots with data from five and four trials with inadequate/unclear allocation concealment were selected for testing. In addition, a total of five trials with adequate allocation concealment were identified. The meta-analysis test results were positive, and keywords for the judgment of adequate allocation concealment were extracted verbatim from the text of the meta-analysis. The extracted keywords indicate ‘central allocation’ as the main criterion for adequate allocation concealment. Criterion II of the CQS-2 was revised accordingly.
Conclusion
Criterion II of the CQS-2 trial appraisal tool was revised. The revised appraisal tool was specified as version CQS-2B.
Origin of Biological Homochirality by Crystallization of an RNA Precursor on a Magnetic Surface
Authors: Ozturk S. Furkan , Liu Ziwei , Sutherland John D. , Sasselov Dimitar D. 
Published: February 2023

Abstract
Homochirality is a signature of life on Earth yet its origins remain an unsolved puzzle. Achieving homochirality is essential for a high-yielding prebiotic network capable of producing functional polymers like ribonucleic acid (RNA) and peptides. However, a prebiotically plausible and robust mechanism to reach homochirality has not been shown to this date. The chiral-induced spin selectivity (CISS) effect has established a strong coupling between electron spin and molecular chirality and this coupling paves the way for breaking the chiral molecular symmetry by spin-selective processes. Magnetic surfaces can act as chiral agents due to the CISS effect and they can be templates for the enantioselective crystallization of chiral molecules. Here we studied the spinselective crystallization of racemic ribo-aminooxazoline (RAO), an RNA precursor, on magnetite (Fe3O4) surfaces, achieving an unprecedented enantiomeric excess of about 60%. Following the initial enrichment, we then obtained homochiral crystals of RAO after a subsequent crystallization. Our work combines two necessary features for reaching homochirality: chiral symmetry-breaking induced by the magnetic surface and self-amplification by conglomerate crystallization of RAO. Our results demonstrate a prebiotically plausible way of achieving systems level homochirality from completely racemic starting materials.