bluuebunny/crossref_metadata_2025_split huggingface dataset:
Habitat functionality: Integrating environmental and geographic space in niche modeling for conservation planning
Authors: Van Moorter Bram , Kivimäki Ilkka , Panzacchi Manuela , Saura Santiago , Brandão Niebuhr Bernardo , Strand Olav , Saerens Marco 
Published: May 2023

AbstractNiche modeling is typically used to assess the effects of anthropogenic land use and climate change on species distributions and to inform spatial conservation planning. These models focus on the suitability of local biotic and abiotic conditions for a species in environmental space (E‐space). Although movements also affect species occurrence, efforts to formally integrate geographic space (G‐space) into niche modeling have been hindered by the lack of comprehensive theoretical frameworks. We propose the “functional habitat” framework to define areas that are simultaneously of high quality in E‐space, and functionally connected to other suitable habitats in G‐space. Originating in metapopulation ecology, approaches have been developed to assess the amount of suitable connected habitats, based on the proximity between pairs of locations. Using network theory, which operates in topological space (T‐space, defined by a network), we extended these metapopulation approaches to integrate movement constraints in G‐space with niche modeling in E‐space. We demonstrate the functional habitat framework using empirical data (GPS tracking and population monitoring) throughout the European wild mountain reindeer (Rangifer t. tarandus) distribution range. We show that functional habitat outperforms traditional suitability in explaining the species' distribution. This approach integrates effects from habitat loss and fragmentation for spatial conservation planning, and avoids overemphasizing small, inaccessible areas with locally suitable habitats. The functional habitat framework formally integrates biotic, abiotic, and movement constraints in niche modeling using network theory, thus opening a wide range of applications in spatial conservation planning.
Renal and blood pressure effects of dapagliflozin in recently hospitalized patients with heart failure with mildly reduced or preserved ejection fraction: Insights from the DELIVER trial
Authors: Chatur Safia , Cunningham Jonathan W. , Vaduganathan Muthiah , Mc Causland Finnian R. , Claggett Brian L. , Desai Akshay S. , Miao Zi Michael , Jhund Pardeep S. , de Boer Rudolf A. , Hernandez Adrian F. , Inzucchi Silvio E. , Kosiborod Mikhail N. , Lam Carolyn S.P. , Martinez Felipe A. , Shah Sanjiv J. , Petersson Magnus , Langkilde Anna Maria , McMurray John J.V. , Solomon Scott D. 
Published: May 2023

AimsPatients recently hospitalized for heart failure (HF) often have unstable haemodynamics and experience worsening renal failure, and are at elevated risk for recurrent HF events. In DELIVER, dapagliflozin reduced HF events or cardiovascular death including among patients who were hospitalized or recently hospitalized.Methods and resultsWe examined the effects of dapagliflozin versus placebo on estimated glomerular filtration rate (eGFR) slope (acute and chronic), 1‐month change in systolic blood pressure, and the occurrence of serious hypovolaemic or renal adverse events in patients with and without HF hospitalization within 30 days of randomization. The 654 (90 randomized during hospitalization, 147 1–7 days post‐discharge and 417 8–30 days post‐discharge) recently hospitalized patients had lower baseline eGFR compared with those without recent HF hospitalization (median [interquartile range] 55 [43, 71] vs. 60 [47, 75] ml/min/1.73 m2). Dapagliflozin consistently reduced the risk of all‐cause (pinteraction = 0.20), cardiac‐related (pinteraction = 0.75), and HF‐specific (pinteraction = 0.90) hospitalizations, irrespective of recent HF hospitalization. In those recently hospitalized, acute placebo‐corrected eGFR reductions with dapagliflozin were modest and similar to patients without recent hospitalization (−2.0 [−4.1, +0.1] vs. −3.4 [−3.9, −2.9] ml/min/1.73 m2, pinteraction = 0.12). Dapagliflozin's effect to slow chronic eGFR decline was similar regardless of recent hospitalization (pinteraction = 0.57). Dapagliflozin had a minimal effect on 1‐month systolic blood pressure and to a similar degree in patients with and without recent hospitalization (−1.3 vs.−1.8 mmHg, pinteraction = 0.64). There was no treatment‐related excess in renal or hypovolaemic serious adverse events, irrespective of recent HF hospitalization.ConclusionIn patients recently hospitalized with HF, initiation of dapagliflozin had minimal effects on blood pressure and did not increase renal or hypovolaemic serious adverse events, yet afforded long‐term cardiovascular and kidney protective effects. These data suggest that the benefit to risk ratio favours initiation of dapagliflozin among stabilized patients hospitalized or recently hospitalized for HF.Clinical Trial Registration:
ClinicalTrials.gov NCT03619213.
Gas‐Free Amino‐ and Alkoxycarbonylation of Aryl Iodides in a Bioinspired Deep Eutectic Solvent with Mo(CO)6 as a Safe CO Source
Authors: Messa Francesco , Paparella Andrea Nicola , Veselý Dominik , Krajčovič Jozef , Papadia Paride , Perrone Serena , Salomone Antonio 
Published: May 2023

AbstractThe Pd‐catalyzed amino‐ and alkoxycarbonylation of aryl iodides has been exploited, for the first time, in a bioinspired Deep Eutectic Solvent and under gas‐free conditions, by using Mo(CO)6 as the CO source. The method allows for the preparation of carboxylic amides and esters in high yields (up to 99 %), short reaction time (2 h) and under mild reaction conditions (80 °C), with a low catalyst loading (2.5 mol %). Noteworthy, in the case of N‐hexylbenzamide, it has been demonstrated that both the catalyst and DES can be used for four consecutive runs, with a moderate decrease of catalytic efficiency. The methodology has been also applied to the preparation of an Active Pharmaceutical Ingredient used for the treatment of human scabies and lice.
Hierarchical structure regulation for sequential steps in solar vapor generation
Authors: Chen Xuanbo , Liu Shuyong , Yang Nailiang , Yu Ranbo , Wang Dan 
Published: May 2023

AbstractIncluding the transpiration of leaves, water evaporation from solar irradiation is a universal phenomenon in nature. Currently, solar vapor generation allows clean water to be obtained from various waterbodies. Since water is transported through porous structures and evaporates on their surfaces, the properties of the nano‐micro structure, especially the surfaces are significantly important. For instance, the surface energy, determined by the localized atomic arrangement, can modify the interactions between water and the substrate. Moreover, the construction of a three‐dimensional hierarchical structure can efficiently enlarge the surface area, and the provided channels play a vital role in mass transfer. In this review, we summarize recent research on the structural regulation in tuning the sequential steps in photo‐vapor generation. We hope this review can provide a rational and systemic basis for the development of advanced solar vapor generating materials, especially from the view of surface engineering.image
Effects of sesame (Sesamum indicum L.) and bioactive compounds (sesamin and sesamolin) on inflammation and atherosclerosis: A review
Authors: Hadipour Elham , Emami Seyed Ahmad , Tayarani‐Najaran Niloufar , Tayarani‐Najaran Zahra 
Published: May 2023

AbstractInflammation, oxidative stress, obesity, infection, hyperlipidemia, hypertension, and diabetes are the main causes of atherosclerosis, which in the long term lead to hardening of the arteries. In the current study, we reviewed recent findings of the mechanism of sesame and its active compounds of sesamin and sesamolin regulates on atherosclerosis. Sesame can decrease the lipid peroxidation and affect the enzymes, which control the balance of oxidative status in the body. Besides modulating the inflammatory cytokines, sesame regulates the main mediators of the signaling pathways in the process of inflammation, such as prostaglandin E2 (PGE2), nuclear factor kappa light‐chain enhancer of activated B cells (NF‐kB) and peroxisome proliferator‐activated receptor gamma (PPAR‐γ). Sesame decreases the growth of different pathogens. It fights against obesity and helps to reduce weight, body mass index (BMI), waist circumference, and lipid count of serum and liver. In addition to lowering fasting blood sugar (FBS), it decreases the hemoglobin A1c (HbA1c) and glucose levels and improves insulin function. With high content of linoleic acid, α‐linolenic acid, and total polyunsaturated fatty acid (PUFA), sesame efficiently controls the blood plasma lipids and changes the lipid profile. In the case of hypertension, it maintains the health of endothelium through multiple mechanisms and conserves the response of the arteries to vasodilation. PUFA in sesame suppresses blood clotting and fibrinogen activity. All the mentioned properties combat atherosclerosis and hardening of blood vessels, which are detailed in the present review for sesame.
Hand anthropometric survey of Iranian healthcare workers
Authors: Zare Asma , Jahangiri Mehdi , Seif Mozhgan , Choobineh Alireza , Tahernejad Somayeh 
Published: May 2023

AbstractBackgroundHand anthropometric data can help properly design hand tools and protective equipment for healthcare workers. This study aimed to measure and analyze the hand anthropometric data of Iranian healthcare workers.MethodsIn this cross‐sectional study, 33 hand dimensions were measured among 540 Iranian healthcare workers (270 male and 270 female) in six ethnic groups. Two‐dimensional imaging and traditional measurement methods were used. The data were classified and compared based on gender and ethnicity.ResultsThe results revealed a difference between the dimensions of males' and females' hands, which indicated that the dimensions of males' hands were larger. The results showed significant differences between different regions of Iran and other countries including the United States, Bangladesh, Nigeria, and Colombia.ConclusionDifferences in hand anthropometric dimensions should be considered in the design and manufacture of hand tools and hand protection equipment to prevent reduced productivity, occupational injuries, and diseases.
Hall current, radiation absorption, and diffusion thermoeffects on unsteady MHD rotating chemically reactive second‐grade fluid flow past a porous inclined plate in the presence of an aligned magnetic field, thermal radiation, and chemical reaction
Authors: Sridevi D. , Murthy Ch. V. Ramana , Varma N. Udaya Bhaskara 
Published: May 2023

AbstractIn this paper, we analyze the effects of Hall current, radiation absorption and diffusion thermo on unsteady magnetohydromagnetic free convection flow of a viscous incompressible electrically conducting and chemically reacting second‐grade fluid past an inclined porous plates in the presence of an aligned magnetic field, thermal radiation, and chemical reaction. An exact analytical solution of the governing equations for fluid velocity, fluid temperature, and species concentration subject to appropriate initial and boundary conditions is obtained using the perturbation technique. Expressions for shear stress, rate of heat transfer, and rate of mass transfer at the plate are derived. The numerical values of primary and secondary fluid velocities, fluid temperature and species concentration are displayed graphically, whereas those of shear stress and rate of mass transfer at the plate are presented in tabular form for various values of pertinent flow parameters. In addition, the skin friction on the boundary, the heat flux expressed in terms of the Nusselt number, and the rate of mass transfer described in the Sherwood number are all derived, and their behavior is studied computationally. It can be deduced that an increase in radiation absorption and hall current parameters over the fluid region increases the velocity produced. The resulting velocity continually increases to a very high level, with contributions coming from thermal and solutal buoyancy forces. Skin friction may decrease by manipulating the rotation parameter, but the Hall effect can worsen it. When the parameter for the chemical reaction increases, there is a concomitant rise in the mass transfer rate.
Exact analytical solution of forced convection through a porous‐saturated duct
Authors: Karimi Shiva , Shivanian Elyas , Barikbin Zahra , Sohrabi Fatemeh 
Published: May 2023

AbstractIn the current paper, the effect of a magnetic field on the fully developed forced convective flow and heat transfer is studied. An exact solution is extracted when the flow in the porous medium is governed by the Brinkman–Forchheimer Extended Darcy model. First, the problem formulation is explained to obtain a new system of mathematical formulation. Then, by utilizing the properties which are imposed into the problem, the exact closed‐form analytical solution of the problem is explored. Finally, the main results are illustrated to show the impact of the porous media‐shaped parameter, magnetic parameter, Forchheimer number, and viscosity ratio. It should be mentioned that the asymptotic results achieved in this study were compared with the exact results and it is found that they are in good agreement.
Data pricing with privacy loss compensation for cyber‐physical systems: A Stackelberg game based approach
Authors: Yang Ming , Feng Honglin , Wang Xin , Wu Xiaoming , Wang Yunfei , Ren Chuanxu 
Published: May 2023

AbstractThe integration of sensors in cyber‐physical systems has given rise to data markets, where data owners can offer their sensing data for sale to potential buyer. However, determining the optimal data price in such markets is a complex issue, which demands a careful consideration of the interests of all parties involved, as well as the potential privacy loss for data sellers. By taking privacy loss into account, this paper proposes a fair compensation model for data sellers and formulates the pricing problem as a Stackelberg game. An automatic data pricing algorithm is developed to calculate the optimal price maximizing the joint benefits of the data sellers and the buyer where the privacy loss of the data sellers are compensated reasonably. Numerical simulations validate the effectiveness of the proposed pricing model in balancing benefits and privacy loss.
Family economic pressure and early adolescents' prosocial behavior: The importance of considering the types of prosocial behavior
Authors: Xiao Sonya Xinyue , Korous Kevin M. , Hewitt Sarah L. , Nguyen Diana 
Published: May 2023

AbstractBackgroundPrior research findings are mixed regarding whether prosocial behavior is positively or negatively related to socioeconomic status and its correlates, such as economic pressure. This may be due to the lack of considerations for the type of prosocial behavior.AimsIn this study, we aimed to examine how six types of prosocial behavior (i.e., public, anonymous, compliant, emotional, dire, and altruistic) are related to economic pressure among early adolescents. We hypothesized that family economic pressure would be associated with each type of prosocial behavior in differing ways.Materials & MethodsParticipants were 11–14 years old (N = 143, Mage = 12.2 years, SDage = 0.87, 63 boys, 1 trans‐identified boy, 55 girls), early adolescents and their parents. Among them, 54.6% were non‐Hispanic/Latinx (NH/L) White, 23.8% were NH/L Black, 11.2% were NH/L Asian, 2.1% were NH/L Multiracial, and 8.4% were Hispanic/Latinx. Parents reported family economic pressure and adolescents' six types of prosocial behavior.ResultsPath analysis revealed that economic pressure was negatively associated with emotional and dire prosocial behavior over and above age, gender, and race/ethnicity. Family economic pressure was unrelated to public, anonymous, compliant, and altruistic prosocial behavior.DiscussionThese findings show some support for the Family Stress Model, such that economic stress might hinder youth's prosocial development. At the same time, youth may have similar levels of certain types of prosocial behavior regardless of their family's economic pressure.ConclusionThis research provided insight into the complex relation between economic pressure and youth's prosocial behavior which varies depending on the type of behavior.
On the political right, the customer is always right: Political ideology, entitlement, and complaining
Authors: Shepherd Steven , Teymouri Athar Hesam , Zaboli Sahel 
Published: May 2023

AbstractAcross three preregistered studies and five supplementary datasets, we predicted and found that conservatives were more inclined to complain than liberals due to conservative consumers feeling a greater sense of entitlement. This research contributes to the literature by introducing consumer entitlement as a novel explanation for ideological differences in consumer behavior, and by building on previous work suggesting that conservative consumers complain less than liberals (Journal of Consumer Research, 2017, 44, 477). Evidence is provided across several service contexts and types of complaining behaviors. Study 1 and 4 supplementary datasets supported the basic process. Next, theory‐relevant boundary conditions provided converging process evidence. In Study 2, complaining intentions decreased among conservatives when they felt less (vs. more) entitled than the target of social comparison. In Study 3, complaining intentions decreased among conservatives when a service recovery was framed as providing special treatment. Implications and future research directions are discussed.
Slo1 deficiency impaired skeletal muscle regeneration and slow‐twitch fibre formation
Authors: Xia Chao , Wang Yonghui , Jiang Tianyuan , Hu Yan , Chen Yang , Ma Xinrun , Zhang Xuemei , Gao Yanhong 
Published: May 2023

AbstractBackgroundIt has been observed that Slo1 knockout mice have reduced motor function, and people with certain Slo1 mutations have movement problems, but there is no answer whether the movement disorder is caused by the loss of Slo1 in the nervous system, or skeletal muscle, or both. Here, to ascertain in which tissues Slo1 functions to regulate motor function and offer deeper insight in treating related movement disorder, we generated skeletal muscle‐specific Slo1 knockout mice, studied the functional changes in Slo1‐deficient skeletal muscle and explored the underlying mechanism.MethodsWe used skeletal muscle‐specific Slo1 knockout mice (Myf5‐Cre; Slo1flox/flox mice, called CKO) as in vivo models to examine the role of Slo1 in muscle growth and muscle regeneration. The forelimb grip strength test was used to assess skeletal muscle function and treadmill exhaustion test was used to test whole‐body endurance. Mouse primary myoblasts derived from CKO (myoblast/CKO) mice were used to extend the findings to in vitro effects on myoblast differentiation and fusion. Quantitative real‐time PCR, western blot and immunofluorescence approaches were used to analyse Slo1 expression during myoblast differentiation and muscle regeneration. To investigate the involvement of genes in the regulation of muscle dysfunction induced by Slo1 deletion, RNA‐seq analysis was performed in primary myoblasts. Immunoprecipitation and mass spectrometry were used to identify the protein interacting with Slo1. A dual‐luciferase reporter assay was used to identify whether Slo1 deletion affects NFAT activity.ResultsWe found that the body weight and size of CKO mice were not significantly different from those of Slo1flox/flox mice (called WT). Deficiency of Slo1 in muscles leads to reduced endurance (~30% reduction, P < 0.05) and strength (~30% reduction, P < 0.001). Although there was no difference in the general morphology of the muscles, electron microscopy revealed a considerable reduction in the content of mitochondria in the soleus muscle (~40% reduction, P < 0.01). We found that Slo1 was expressed mainly on the cell membrane and showed higher expression in slow‐twitch fibres. Slo1 protein expression is progressively reduced during muscle postnatal development and regeneration after injury, and the expression is strongly reduced during myoblast differentiation. Slo1 deletion impaired myoblast differentiation and slow‐twitch fibre formation. Mechanistically, RNA‐seq analysis showed that Slo1 influences the expression of genes related to myogenic differentiation and slow‐twitch fibre formation. Slo1 interacts with FAK to influence myogenic differentiation, and Slo1 deletion diminishes NFAT activity.ConclusionsOur data reveal that Slo1 deficiency impaired skeletal muscle regeneration and slow‐twitch fibre formation.
Validation of a telephone‐based administration of the simplified nutritional appetite questionnaire
Authors: Thai Binh Duong , Bauer Jürgen M. , Eidam Annette , Durga Jane , Grund Stefan , Mross Thomas , Benzinger Petra 
Published: May 2023

AbstractBackgroundAnorexia of aging is characterized by an age‐associated reduction of appetite, whose aetiology in most cases is multifactorial and which often triggers malnutrition. The Simplified Nutritional Appetite Questionnaire (SNAQ) is an established screening tool. This study aimed to investigate reliability, validity, and feasibility of its telephone administration (T‐SNAQ) in German community‐dwelling older adults.MethodsThis cross‐sectional single‐centre study recruited participants from April 2021 to September 2021. First, the SNAQ was translated into German according to an established methodology. After translation, reliability, construct validity, and feasibility of the T‐SNAQ were analysed. A convenience sample of community‐dwelling older adults aged ≥70 years was recruited. The following measurements were applied to all participants: T‐SNAQ, Mini Nutritional Assessment – Short Form (MNA‐SF), six‐item Katz index of independence in activities of daily living (ADL), eight‐item Lawton instrumental activities of daily living (IADL), telephone Montreal Cognitive Assessment (T‐MoCA); FRAIL scale, Geriatric Depression Scale (GDS‐15) and Charlson co‐morbidity index as well as daily caloric and protein intake.ResultsOne hundred twenty participants (59.2% female) with a mean age of 78.0 ± 5.8 years were included in the present study. The percentage of participants identified with poor appetite based on T‐SNAQ was 20.8% (n = 25). T‐SNAQ showed a good internal reliability with a Cronbach's alpha coefficient of 0.64 and a good test–retest reliability [intraclass coefficient of 0.95 (P < 0.05)]. Regarding construct validity, T‐SNAQ was significantly positively correlated with MNA‐SF (r = 0.213), T‐MoCA (r = 0.225), daily energy (r = 0.222) and protein intake (r = 0.252) (P < 0.05). It also demonstrated a significant negative association with GDS‐15 (r = −0.361), FRAIL scale (r = −0.203) and Charlson co‐morbidity index (r = −0.272). Regarding applicability, the mean time for T‐SNAQ was 95 s and completion rate was 100%.ConclusionsThe T‐SNAQ is a feasible screening instrument for anorexia of aging in community‐dwelling older adults via telephone interviews.
Current and emerging technologies for defining and validating tendon cell fate
Authors: Huang Alice H. , Galloway Jenna L. 
Published: May 2023

AbstractThe tendon field has been flourishing in recent years with the advent of new tools and model systems. The recent ORS 2022 Tendon Section Conference brought together researchers from diverse disciplines and backgrounds, showcasing studies in biomechanics and tissue engineering to cell and developmental biology and using models from zebrafish and mouse to humans. This perspective aims to summarize progress in tendon research as it pertains to understanding and studying tendon cell fate. The successful integration of new technologies and approaches have the potential to further propel tendon research into a new renaissance of discovery. However, there are also limitations with the current methodologies that are important to consider when tackling research questions. Altogether, we will highlight recent advances and technologies and propose new avenues to explore tendon biology.