bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilization of Agricultural Waste as Low-Cost Adsorbents in Dye Wastewater Treatment: Kinetic and Thermodynamic Study
Authors: Abbas Afiaa Hussein , AlJaberi Forat Yasir 
Published: July 2023

Abstract
In recent years, the treatment of dye wastewater has attracted more attention because of its harmful impact on the environment. Therefore, dye wastewater should be treated using effective treatment methods, such as adsorption, which is widely employed to remediate many dyes from wastewater. This work studied the use of Laurus Nobilis Leaves (LNL) and sawdust (SD) as low-cost natural adsorbents to remediate reactive blue (RB) dye from synthetic wastewater under the influence of their dosages (0.5-5.5 g) for each, pH (3-9), and contact time (10-190 min). The experimental design, analysis of results, and optimization were conducted using Response Surface Methodology (RSM) based on Box-Behnken method (BBM) and the Minitab-Statistical program. The BET and FT-IR tests have been used to characterize these adsorbents, which show that SD-adsorbent includes more pore volume and surface area than LNL-adsorbent. The adsorption isotherms study revealed that Langmuir isotherm was a more fitted model than Freundlich model. Adsorption kinetic shows that the current adsorption process obeys the pseudo-second order model (R2=0.998) compared to the pseudo-first order model (R2=0.973) and the intraparticle diffusion model (R2=0.915). Thermodynamics study revealed that the present adsorption is endothermic, random irregularity at the solid-liquid, and a spontaneous nature. More than 60% of RB-dye removal efficiency was achieved at the optimal conditions, which were 5.5 g of SD-adsorbent, 0.8 g of LNL-adsorbent, pH 3, and 141 min of the contact time. The core results proved that the interaction effect of using multi-natural adsorbents was significant and cost-effective, providing considerable removal of dye from wastewater.
Design of a Test to Identify Mutagenic Effects of Hair Dye using Proteus mirabilis
Authors: Hezam Abbas Mayar , Yousif Maitham Ghaly , Mohammed Ghaidaa Jihadi 
Published: July 2023

Abstract
The purpose of this study was to determine the possible mutagenicity of hair dye using the auxotroph’s methionine Proteus Mirabilis as a test. The Ames test was employed to identify reverse mutations in auxotroph’s P. Mirabilis treated with hair dyes. The results demonstrated a significant increase (P< 0.05) in reverse colonies of auxotroph’s P. mirabilis treated with 250 and 500 mg/mL of hair dyes in comparison to the negative control. Reverse mutations in the metE gene of the auxotroph’s P. Mirabilis were identified using DNA sequencing and polymerase chain reaction. The results confirmed the presence of the metE gene at a percentage of (100%) in all isolates treated with hair dyes at 250 and 500 mg/mL. Using BLAST software, the metE gene’s sequence was compared to the gene sequence of a standard isolate. Point mutations in the DNA of the metE gene altered protein translation, according to a genetic study of metE gene isolates treated with hair dyes. Finally, point mutations in the metE genes were identified using amino acid translation analysis of auxotroph’s P. mirabilis isolates treated with hair dyes. Point mutations in the metE gene cause many amino acids to be converted to methionine, which enables auxotroph’s P. mirabilis to grow without the need for methionine from an external source. The study found that the test for identifying mutagens in hair dyes was simple to use and cheap. It has also shown high efficacy in altering the amino acid and nitrogenous base sequences in the metE genes, thus their effect on methionine synthesis.
Efficacy and Safety of Ocedurenone: Subgroup Analysis of the BLOCK-CKD Study
Authors: Bakris George L , Yang Y Fred , McCabe James M , Liu Jin Rong , Tan Xiaojuan J , Benn Vincent J , Pitt Bertram 
Published: July 2023

Abstract

BACKGROUND
Ocedurenone (KBP-5074), a nonsteroidal mineralocorticoid receptor antagonist, is documented to lower blood pressure in patients with stage 3b/4 chronic kidney disease (CKD) with uncontrolled or resistant hypertension (BLOCK-CKD study). However, the efficacy and safety of Ocedurenone in subgroups such as Hispanic patients or those with stage 4 CKD, diabetes, or very high albuminuria have not been reported.

METHODS
A total of 162 patients were enrolled in the BLOCK-CKD study. The primary endpoint of these analyses was change in systolic blood pressure (SBP) from baseline to day 84. Prespecified subgroup analysis of SBP focused on demographic (e.g., ethnicity, age) and medical (e.g., CKD stage, diabetes, albuminuria, baseline estimated glomerular filtration rate [eGFR]). The safety analysis focused on changes in serum potassium levels from baseline.

RESULTS
SBP reductions were consistent across subgroups compared with the overall study cohort. Placebo-adjusted SBP reductions were observed in Hispanic patients (−8.1 and −9.9 mm Hg for 0.25 and 0.5 mg, respectively, total n = 35) and patients with CKD stage 4 (−9.3 and −10.4 mm Hg for 0.25 and 0.5 mg, respectively, total n = 64), diabetes (−6.9 and −11.6 mm Hg for 0.25 and 0.5 mg, respectively, total n = 51), and very high albuminuria (−13.1 and −12.3 mm Hg for 0.25 and 0.5 mg, respectively, total n = 85). Changes in serum potassium were similar across all patient subgroups regardless of baseline eGFR, diabetes status, or degree of proteinuria. No cases of hyperkalemia required intervention or resulted in study discontinuation.

CONCLUSIONS
Ocedurenone consistently reduced in SBP in all patient subgroups. Moreover, while small elevations in serum potassium occurred, they were not associated with Ocedurenone or study discontinuation.
Comprehensive profiling identifies tumour and immune microenvironmental differences in clinical subsets of cutaneous squamous cell carcinoma
Authors: Thai Alesha A , Young Richard J , Bressel Mathias , Angel Christopher , McDowell Lachlan , Tiong Albert , Bucknell Nicholas W , Fellowes Andrew , Xu Huiling , Trigos Anna , Rischin Danny , Solomon Benjamin J 
Published: July 2023

Abstract

Background
Cutaneous squamous cell carcinomas (cSCCs) are the second most diagnosed skin cancer worldwide; however, little is known about the pathobiological factors that contribute to the diverse clinical outcomes seen.

Objectives
To profile cSCCs comprehensively and identify the pathological processes that contribute to the disparities seen in their clinical behaviour.

Methods
We characterized the genomic, transcriptomic and immunohistochemical profiles of 211 cSCC tumours, including 37 cSCCs from immunocompromised patients.

Results
cSCCs from immunocompromised patients were characterized by a lack of B cells in the peritumoral stroma compared with immunocompetent patients. Further, an abundance of a memory B-cell-like population in the peritumoral stroma was associated with a better prognosis in all patients (immunocompetent and immunocompromised), as well as only immunocompetent patients. No differences in genetic ­variants, tumour mutational burden or mutational signatures were observed between cSCCs from immunocompetent and immunocompromised patients. Thus, differences in survival between cSCCs from immunocompromised patients and immunocompetent patients are not likely to be driven by tumour genomic factors, but may be associated with differential host immune response. cSCC not from a primary head and neck site had lower tumour mutational burden and exhibited upregulation of the epithelial–mesenchymal transition programme compared with head and neck cSCC. Both factors were implicated with poorer responses to immune checkpoint inhibition, and the latter with poorer survival.

Conclusions
We identified tumour and host immune factors that contribute to the disparate clinical behaviour of cSCC, with broad translational application, including prognostication, treatment prediction to current therapies and the identification of novel anticancer therapy approaches in cSCC.
Major improvement of very severe alopecia areata in patients treated with the combination of baricitinib and low doses of corticosteroids: an eight-case series
Authors: Hébert Vivien , Joly Pascal 
Published: July 2023

Abstract
Alopecia areata (AA), especially very severe types, causes patients severe psychological and social distress. Although baricitinib alone has been shown to be effective in conferring complete hair regrowth (HR) in severe AA [Severity of Alopecia Tool (SALT) score 50–94], it gave poor therapeutic results in very severe AA (SALT score ≥ 95). Methotrexate alone is similarly ineffective, but in a recent study of patients with areata totalis or universalis, low-dose prednisone with methotrexate gave a 20% rate of HR, and was effective and well tolerated. In our study of baricitinib 4 mg + prednisone 20 mg per day tapered over 3 months to treat eight women with very severe AA, seven of eight achieved complete HR (SALT score 0) and one had partial HR (SALT score 30).
Habit-reversal training: a psychotherapeutic approach in treating body-focused repetitive behaviour disorders
Authors: Rahman Syed Minhaj , Jafferany Mohammad , Barkauskaite Ruta 
Published: July 2023

Abstract
Body-focused repetitive behaviours (BFRBs) are recurrent, compulsive, destructive behaviours directed towards the body. Although studies have demonstrated a 12–14% prevalence rate, researchers found that dermatologists and psychiatrists show a lack of knowledge regarding psychodermatology resources and information about BFRB disorders (BFRBDs) such as trichotillomania (TTM). There is limited research about treatments including ones investigating the clinical applications of various self-help training such as decoupling (DC) and DC in sensu (DC-is) as well as about habit-reversal training (HRT). HRT is a five-component behavioural intervention that aims to develop a competing response to a specific unwanted behaviour. Studies have found substantial support for HRT’s efficacy in treating a variety of maladaptive repetitive behaviours including onychotillomania, TTM, skin-picking disorder and chronic cheek biting. Additionally, many psychotherapies can augmented HRT. Psychotherapies include acceptance and commitment therapy, dialectical behaviour therapy, psychodynamic psychotherapy, mindfulness mediation and the cognitive psychophysiological model. A recently investigated variant of HRT, DC-is, resulted in consistently satisfactory objective and subjective improvement for treating BFRBDs, and HRT showed good subjective but poor objective improvement compared with standard DC. HRT and HRT variants are effective therapeutic treatments for BFRBDs; however, further randomized double-blinded and placebo-controlled trials are required to examine HRT’s therapeutic profile.
Long noncoding RNAs contribute to DNA damage resistance in Arabidopsis thaliana
Authors: Durut Nathalie , Kornienko Aleksandra E , Schmidt Heiko A , Lettner Nicole , Donà Mattia , Nordborg Magnus , Mittelsten Scheid Ortrun 
Published: July 2023

Abstract
Efficient repair of DNA lesions is essential for the faithful transmission of genetic information between somatic cells and for genome integrity across generations. Plants have multiple, partially redundant, and overlapping DNA repair pathways, probably due to the less constricted germline and the inevitable exposure to light including higher energy wavelengths. Many proteins involved in DNA repair and their mode of actions are well described. In contrast, a role for DNA damage-associated RNA components, evident from many other organisms, is less well understood. Here, we have challenged young Arabidopsis thaliana plants with two different types of genotoxic stress and performed de novo assembly and transcriptome analysis. We identified three long noncoding RNAs (lncRNAs) that are lowly or not expressed under regular conditions but up-regulated or induced by DNA damage. We generated CRISPR/Cas deletion mutants and found that the absence of the lncRNAs impairs the recovery capacity of the plants from genotoxic stress. The genetic loci are highly conserved among world-wide distributed Arabidopsis accessions and within related species in the Brassicaceae group. Together, these results suggest that the lncRNAs have a conserved function in connection with DNA damage and provide a basis for mechanistic analysis of their role.
Optimal allocation method of hybrid energy storage capacity of multi-energy system under low-carbon background
Authors: Wang Xiran , Sun Ke , Yang Xuan , Yang Kai , Chen Jiaxi 
Published: July 2023

Abstract
The energy dispatching and distribution ability is improved by optimizing the configuration of hybrid energy storage capacity of multi-energy system in low-carbon background, and an optimal configuration method of hybrid energy storage capacity of multi-energy system in low-carbon background based on equilibrium control and dynamic optimization algorithm is proposed. The data structure model of hybrid energy storage capacity distribution of multi-energy system is constructed. Under the condition that the energy storage optimal allocation model based on cost analysis meets the system performance index, the energy storage optimal allocation model is established with the objective function of minimizing the cost of configuring energy storage system, and with the objective of minimizing the fluctuation of active power of distributed power sources, such as wind and light. Taking the penalty cost of wind energy storage combined output power exceeding the fluctuation limit as the objective function, low-pass filtering method is adopted to stabilize the fluctuation of new energy power, and the optimal configuration capacity of energy storage system is determined according to the allowable frequency deviation and voltage stability of the system. Balanced control and dynamic optimization algorithm are adopted to realize the optimal configuration of hybrid energy storage capacity of multi-energy system under low-carbon background by combining different wind and solar energy combinations, different sampling intervals and different number of power stations. The simulation results show that the hybrid energy storage capacity allocation of multi-energy system has strong adaptability and high environmental adaptability, which effectively improves the transient stability of power grid system and further promotes the safe and stable operation of power grid system.
Research on the factors influencing college students’ energy-use behavior in dormitories: group-level factors and time factors
Authors: Liu Xiaodan , Yang Yanping , Guo Liang , Liao Ling , Xiao Lin 
Published: July 2023

AbstractPromoting energy-saving behavior among college students in dormitories is conducive to improving the energy efficiency of college buildings. As students in the same dormitory need to share the energy-using equipment and expenses, they will inevitably influence each other by their energy-use behaviors, and this interaction process will gradually reach a certain stable state with the passing of the time spent with roommates. However, the existing research on the influencing factors of energy-use behaviors often focuses on individual subjective characteristics while overlooking the influence of group and time factors. Therefore, this paper incorporates interpersonal relationship and group identity into the theory of planned behavior, and considers the time spent with roommates as the moderating variable to build a model of factors influencing college students’ energy-use behaviors in their dormitories. Empirical data were collected by a questionnaire survey with 768 respondents, and generalized ordered logit regression was used to analyze the research model. The results reveal that the factors that influence students’ energy-use behaviors will change with the time spent with roommates. When the time spent with roommates is 0–1 year, interpersonal relationships, group identity, comfort, individual norms, and environmental concerns are significant influences. When the time spent with roommates is 1–2 years, environmental concerns will no longer have an effect; however, energy-use costs and energy-use habits will be added. When the time spent with roommates is 2–3 years, interpersonal relationships, individual norms, group identity, and energy-use costs will no longer have any influence, but subjective norm will be added.
On the reduction in accuracy of finite difference schemes on manifolds without boundary
Authors: Hamfeldt Brittany Froese , Turnquist Axel G R 
Published: July 2023

Abstract
We investigate error bounds for numerical solutions of divergence structure linear elliptic partial differential equations (PDEs) on compact manifolds without boundary. Our focus is on a class of monotone finite difference approximations, which provide a strong form of stability that guarantees the existence of a bounded solution. In many settings including the Dirichlet problem, it is easy to show that the resulting solution error is proportional to the formal consistency error of the scheme. We make the surprising observation that this need not be true for PDEs posed on compact manifolds without boundary. We propose a particular class of approximation schemes built around an underlying monotone scheme with consistency error $O(h^{\alpha })$. By carefully constructing barrier functions, we prove that the solution error is bounded by $O(h^{\alpha /(d+1)})$ in dimension $d$. We also provide a specific example where this predicted convergence rate is observed numerically. Using these error bounds, we further design a family of provably convergent approximations to the solution gradient.
The impact of thiamethoxam on the feeding and behavior of 2 soybean herbivore feeding guilds
Authors: Lee Scott T , Davis Jeffrey A 
Published: July 2023

Abstract
Over the past few decades, inadvertent consequences have stemmed from the intensified use of neonicotinoids in agroecosystems. Neonicotinoid applications can result in both positive (e.g., reduced persistent virus transmission) and negative (e.g., increased host susceptibility) repercussions exhibiting ambiguity for their use in crop production. In soybean, aspects of neonicotinoid usage such as the impact on nonpersistent virus transmission and efficacy against nontarget herbivores have not been addressed. This study evaluated the interaction between the neonicotinoid thiamethoxam and soybean variety and the impact on different pest feeding guilds. Feeding and behavioral bioassays were conducted in the laboratory to assess the effect of thiamethoxam on the mortality and weight gain of the defoliator, Chrysodeixis includens (Walker). Bioassays evaluated impacts dependent and independent of soybean tissue, in addition to both localized and systemic efficacy within the soybean plant. Additionally, using the electrical penetration graph technique (EPG), the probing behavior of 2 piercing-sucking pests, Aphis gossypii Glover and Myzus persicae (Sulzer), was observed. Results from defoliator bioassays revealed thiamethoxam had insecticidal activity against C. includens. Distinctions in thiamethoxam-related mortality between bioassays dependent and independent of soybean tissue (~98% versus ~30% mortality) indicate a contribution of the plant towards defoliator-related toxicity. Observations of defoliator feeding behavior showed a preference for untreated soybean tissue relative to thiamethoxam-treated tissue, suggesting a deterrent effect of thiamethoxam. EPG monitoring of probing behavior exhibited a minimal effect of thiamethoxam on piercing-sucking herbivores. Findings from this study suggest neonicotinoids like thiamethoxam may provide some benefit via insecticidal activity against nontarget defoliators.
Helium as a signature of the double detonation in Type Ia supernovae
Authors: Collins Christine E , Sim Stuart A , Shingles Luke J , Gronow Sabrina , Röpke Friedrich K , Pakmor Rüdiger , Seitenzahl Ivo R , Kromer Markus 
Published: July 2023

ABSTRACT
The double detonation is a widely discussed mechanism to explain Type Ia supernovae from explosions of sub-Chandrasekhar mass white dwarfs. In this scenario, a helium detonation is ignited in a surface helium shell on a carbon/oxygen white dwarf, which leads to a secondary carbon detonation. Explosion simulations predict high abundances of unburnt helium in the ejecta, however, radiative transfer simulations have not been able to fully address whether helium spectral features would form. This is because helium can not be sufficiently excited to form spectral features by thermal processes, but can be excited by collisions with non-thermal electrons, which most studies have neglected. We carry out a full non-local thermodynamic equilibrium radiative transfer simulation for an instance of a double detonation explosion model, and include a non-thermal treatment of fast electrons. We find a clear He i λ10830 feature which is strongest in the first few days after explosion and becomes weaker with time. Initially this feature is blended with the Mg ii λ10927 feature but over time separates to form a secondary feature to the blue wing of the Mg ii λ10927 feature. We compare our simulation to observations of iPTF13ebh, which showed a similar feature to the blue wing of the Mg ii λ10927 feature, previously identified as C i. Our simulation shows a good match to the evolution of this feature and we identify it as high velocity He i λ10830. This suggests that He i λ10830 could be a signature of the double detonation scenario.
An emerging and enigmatic spectral class of isolated DAe white dwarfs
Authors: Elms Abbigail K , Tremblay Pier-Emmanuel , Gänsicke Boris T , Swan Andrew , Melis Carl , Bédard Antoine , Manser Christopher J , Munday James , Hermes J J , Dennihy Erik , Nitta Atsuko , Zuckerman Ben 
Published: July 2023

ABSTRACT
Two recently discovered white dwarfs, WD J041246.84 + 754942.26 and WD J165335.21 − 100116.33, exhibit Hα and Hβ Balmer line emission similar to stars in the emerging DAHe class, yet intriguingly have not been found to have detectable magnetic fields. These white dwarfs are assigned the spectral type DAe. We present detailed follow-up of the two known DAe stars using new time-domain spectroscopic observations and analysis of the latest photometric time-series data from TESS and ZTF. We measure the upper magnetic field strength limit of both stars as B &lt; 0.05 MG. The DAe white dwarfs exhibit photometric and spectroscopic variability, where in the case of WD J041246.84 + 754942.26 the strength of the Hα and Hβ emission cores varies in antiphase with its photometric variability over the spin period, which is the same phase relationship seen in DAHe stars. The DAe white dwarfs closely cluster in one region of the Gaia Hertzsprung–Russell diagram together with the DAHe stars. We discuss current theories on non-magnetic and magnetic mechanisms which could explain the characteristics observed in DAe white dwarfs, but additional data are required to unambiguously determine the origin of these stars.