bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre-selection in cointegration-based pairs trading
Authors: Brunetti Marianna , De Luca Roberta 
Published: May 2023

AbstractThe paper compares the final profitability of a cointegration-based pairs trading strategy when pairs of stocks are pre-selected by means of seven different measures. Some of the measures considered have been extensively used in the pairs trading literature, while others represent a novelty in this type of application. We find that pre-selection matters, since the excess returns remarkably vary, in terms of both average and variability, depending on the metrics used. Differences in profitability by pre-selection metrics are retrieved even after considering commissions and cut rules, market impact, a stricter definition of the Spread reversion to the equilibrium and alternative cointegration tests. Besides, the pairs trading profitability is found to be heterogeneous across the different pre-selection metrics also in terms of exposure to the systematic stock-market risk factors.
Bioleaching metal-bearing wastes and by-products for resource recovery: a review
Authors: Tezyapar Kara I. , Kremser K. , Wagland S. T. , Coulon F. 
Published: May 2023

AbstractThe global transition to a circular economy calls for research and development on technologies facilitating sustainable resource recovery from wastes and by-products. Metal-bearing materials, including electronic wastes, tailings, and metallurgical by-products, are increasingly viewed as valuable resources, with some possessing comparable or superior quality to natural ores. Bioleaching, an eco-friendly and cost-effective alternative to conventional hydrometallurgical and pyrometallurgical methods, uses microorganisms and their metabolites to extract metals from unwanted metal-bearing materials. The performance of bioleaching is influenced by pH, solid concentration, energy source, agitation rate, irrigation rate, aeration rate, and inoculum concentration. Optimizing these parameters improves yields and encourages the wider application of bioleaching. Here, we review the microbial diversity and specific mechanisms of bioleaching for metal recovery. We describe the current operations and approaches of bioleaching at various scales and summarise the influence of a broad range of operational parameters. Finally, we address the primary challenges in scaling up bioleaching applications and propose an optimisation strategy for future bioleaching research.
Functional capacity and inflammatory biomarkers as predictors for right atrial volume index in COPD patients
Authors: Khedr Lamiaa , Khedr Naglaa F. , Werida Rehab H. 
Published: May 2023

Abstract
Objective
Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality and right-heart complications. So, this study aimed to evaluate the role of right atrial volume index (RAVI), inflammatory biomarkers and functional capacity in predicting poor outcomes for patients with COPD, classified by COPD assessment test (CAT) questionnaire, as early predictors of right heart diseases.

Methods
151 patients with COPD with ejection fraction (LVEF) > 55% were enrolled and classified according to CAT questionnaire into CAT ≥ 10 (group I) and CAT < 10 (group II). RAVI was calculated using Echocardiography. Assessment of RV systolic function was done by Doppler imaging. Functional capacity parameters were assessed by modified medical research council dyspnea scale (mMRC). IL-1β, adiponectin, hs-CRP and neopterin were evaluated by ELSA kits.

Results
Group I (CAT ≥ 10) had higher RAVI (73.92 ± 21.20 ml/m2 vs 22.73 ± 6.24 ml/m2, p < 0.001), lower S`tri (0.05 ± 0.01 vs 0.13 ± 0.03 m/s, p < 0.001), lower tricuspid annular plane systolic excursion (TAPSE) (1.20 ± 0.17 cm vs 2.17 ± 0.48 cm, p < 0.001), higher RVSP (54.88 ± 7.97 vs 26.79 ± 9.84 mmHg, p < 0.001) compared with group II (CAT < 10). RAVI was good predictor of CAT (r = 0.954, p < 0.001) and strongly correlated with tricuspid S`tri, RVSP, tricuspid E/e′ and Mitral E/e′ (r = −0.737, r = 0.753, r = 0.817 and r = 0.515, respectively, p < 0.001). RAVI was correlated with TAPSE (r = −0.673, p < 0.001) and with tricuspid E/A ratio & LVEF (r = 0.628, r = −0.407, respectively, p < 0.001). Hs-CRP: 2.50 ± 1.43 vs 2.03 ± 1.19, IL-1β: 37.96 ± 14.35 vs 27.57 ± 8.06, neopterin: 91.37 ± 17.30 vs 76.90 ± 16.75, p < 0.05) were significantly higher besides lower adiponectin levels (3.19 ± 1.98 vs 5.32 ± 1.33 p < 0.05) in group I as compared to group II.

Conclusion
Functional capacity might be useful predictor for right heart diseases in COPD patients. Inflammatory biomarkers, low adiponectin and high Hs-CRP, IL-1β and neopterin levels, might not only be useful to monitor treatment response but may also help to discriminate patients with a worsen prognosis.
Proteomics Analysis of Meat to Identify Goat Intramuscular Fat Deposits Potential Biomarkers
Authors: Xie Yuchun , Zhang Chongyan , Qin Qing , Li Xuewu , Guo Juntao , Dai Dongliang , Wang Zhixin , Zhao Yanhong , Su Rui , Wang Zhiying , Wang Ruijun , Zhang Yanjun , Li Jinquan , Liu Zhihong 
Published: May 2023

AbstractIntramuscular fat (IMF) is a central attribute of goat nutrition qualities and consumers’ choice. Here, we reported potential markers of IMF deposits in goat meat. Based on IMF content that was significantly higher in longissimus dorsi (LD) than in biceps femoris (BF) (P < 0.01), goats were divided into a high-IMF (HI) group (n = 6) and a low-IMF (LI) group (n = 6). To better understand the molecular variations underlying IMF anabolism and catabolism in goats, we performed a proteomic analysis of the HI group and LI group, and 110 differentially expressed proteins (DEPs) were identified. After bioinformatics analysis of GO, KEGG, and protein–protein interaction (PPI), 6 DEPs (HADHA, HADHB, ACSL1, ACADS, ACAT1, and ACAA2) have positive contributions to the regulatory machinery of IMF position. Finally, a potential mRNA–miRNA–protein regulatory network of IMF was created, and the results demonstrated that ACADS and ACSL1 were identified as candidate biomarkers for IMF deposits that are worthy to evaluate in the future. Our study lays a foundation for further improving the meat quality of these animals.
Fasting plasma glucose and serum 25-hydroxy vitamin D levels in individuals with Middle Eastern and Swedish descent
Authors: Taloyan Marina , Steiner Kristin Hjörleifdottir , Östenson Claes-Göran , Salminen Helena 
Published: May 2023

Abstract
Purpose
To determine fasting plasma glucose and serum 25-hydroxyvitamin D (s-25(OH)D) levels and associations between abnormal fasting plasma glucose levels and inadequate s-25(OH)D levels in individuals of Middle Eastern and Swedish descent.

Methods
Observational study with individuals without a diabetes diagnosis, 54.5% of Swedish descent and 45.5% of Middle Eastern descent. In total, 830 participants from two primary healthcare centres in Flemingsberg and Jakobsberg, which are southern and northern suburbs, respectively, of Stockholm, Sweden were included in the study.

Results
Prevalence of inadequate s-25(OH)D levels (at or below 50 nmol/L) was 67.2% among those of Middle Eastern descent and 20.5% among those of Swedish descent (P < 0.001). S-25(OH)D levels correlated weakly positively with fasting plasma glucose levels (ρ = 0.20, P = 0.002) in individuals of Middle Eastern descent. Being of Middle Eastern descent (OR 6.7, 95% CI 4.3–10.4) and having abnormal fasting plasma glucose (OR 1.8, 95% CI 1.2–2.9) were independent predictors of having inadequate s-25(OH)D levels.

Conclusions
Healthcare in Sweden should consider testing fasting plasma glucose and s-25(OH)D levels, particularly in individuals of Middle Eastern descent. The unclear relationship between vitamin D and glucose levels warrants investigation.
Businesses create more jobs in countries with higher share of immigrants because of skill complementarity
Authors: Gutiérrez-Romero Roxana 
Published: May 2023

AbstractPurposePast and recent immigration flows have made societies increasingly more diverse, with important implications for the economy. This article investigates the empirical relationship between ethnic, and birthplace immigration diversity on job creation and entrepreneurship.Design/methodology/approachWe use multilevel modelling and the Global Entrepreneurship Monitor adult population survey across 60 countries from 2001 to 2018.FindingsAs earlier literature, we find that people have a higher probability of becoming entrepreneurs in more ethnically diverse countries. Nonetheless, businesses located in more ethnically diverse countries hire fewer employees. Businesses, on the other hand, create more jobs in countries with a higher proportion of skilled and unskilled immigrants due to skill complementarity.Research originalityContrary to commonly held views, our findings suggest that ethnic and immigration diversity have opposing effects on entrepreneurship and provide important insights into the debate over the economic impact of immigration.
A Systematic Review and Meta-analysis of Electrophysiological Studies of Online Social Exclusion: Evidence for the Neurobiological Impacts of Cyberbullying
Authors: Mills Lia , Driver Christina , McLoughlin Larisa T. , Anijärv Toomas Erik , Mitchell Jules , Lagopoulos Jim , Hermens Daniel F. 
Published: May 2023

AbstractCyberbullying is an increasingly problematic psychosocial health risk, particularly in youth. Electroencephalography (EEG) is commonly utilized to investigate the potential effects of social behaviors on brain activity. Hence, the current paper provides a systematic review of EEG-related studies that have addressed cyberbullying-like behaviors. Initial searches from 4 databases returned 1150 unique articles, which were screened according to PRISMA guidelines. The 29 articles remaining after full text screening investigated online social exclusion, a method of cyberbullying. Across these studies, there was evidence of links between social exclusion and abnormalities in a range of event related potential (ERP) and EEG measures representative of deviance detection (“N2” ERP), response to detection (“P3” ERP), emotional attention (“late slow wave” ERP) and emotional regulation (“frontal theta” EEG). Meta-analysis demonstrated increased P3 and late slow wave amplitudes in response to social exclusion, as well as increases in frontal-medial theta power, particularly in child and adolescent samples. However, many studies had small sample sizes, and lacked longitudinal insight into the effects of recurrent ostracism on brain function. Future research should explore the effects of a broader range of cyberbullying behaviors on psychophysiology longitudinally, particularly in vulnerable populations such as adolescents.
Hermeneutik des Decknamens
Authors: Mohagheghi Yashar 
Published: May 2023

ZusammenfassungMallarmés Dichtung gilt als der Höhepunkt einer selbstreferentiellen Dichtung des l’art pour l’art. In den letzten Jahrzehnten indes hat die Forschung verstärkt Mallarmés Bezug zur Alltagskultur hervorgehoben. Dieser zeigt sich besonders deutlich in der Modezeitschrift La Dernière Mode, die Mallarmé im Jahr 1874 in acht Ausgaben allein verfasst hat. Die Spannung zwischen den Autonomieanforderungen der hohen Kunst und der Populärkultur thematisiert die Zeitschrift dabei selbst. Das zeigt sich auch im Gebrauch der für Modezeitschriften zeittypischen Pseudonyme. Diese gehen über eine rein pragmatische Funktion hinaus und eröffnen ein literarisiertes Spiel der Allusionen und Verweise, das zur Deutung einlädt. Die Hermeneutik des Decknamens erweist sich als Geschlechtertravestie und reflektiert das geschlechtlich kodierte Verhältnis von Hoch- und Populärkultur.
An online fast multi-track locating algorithm for high-resolution single-event effect test platform
Authors: Hu Yu-Xiao , Yang Hai-Bo , Zhang Hong-Lin , Liao Jian-Wei , Mai Fa-Tai , Zhao Cheng-Xin 
Published: May 2023

AbstractTo improve the efficiency and accuracy of single-event effect (SEE) research at the Heavy Ion Research Facility at Lanzhou, Hi’Beam-SEE must precisely localize the position at which each heavy ion hitting the integrated circuit (IC) causes SEE. In this study, we propose a fast multi-track location (FML) method based on deep learning to locate the position of each particle track with high speed and accuracy. FML can process a vast amount of data supplied by Hi’Beam-SEE online, revealing sensitive areas in real time. FML is a slot-based object-centric encoder–decoder structure in which each slot can learn the location information of each track in the image. To make the method more accurate for real data, we designed an algorithm to generate a simulated dataset with a distribution similar to that of the real data, which was then used to train the model. Extensive comparison experiments demonstrated that the FML method, which has the best performance on simulated datasets, has high accuracy on real datasets as well. In particular, FML can reach 238 fps and a standard error of 1.6237 μm. This study discusses the design and performance of FML.
A Novel Handheld Spectroscopy Tool for Detection of Lymphedema
Authors: Sibley Jennifer , Baldwin Jarren , Pamplin John , Rodrick Julia , Liu Charles , Hettrick Heather , Doraiswamy Anand 
Published: May 2023

AbstractThe abstract provides an overview of lymphedema, a chronic and progressive lymphatic disorder that affects millions of people globally. This condition is associated with high costs and comorbidity, with limited treatment options available. Phlebolymphedema, a common form of secondary lymphedema, is linked to the combined effects of lymphatic and chronic venous insufficiencies. Early intervention is crucial to managing the condition; however, early detection remains challenging due to the lack of reliable diagnostic tools. This case study evaluates the clinical utility of a portable tissue analytical tool in a subject with bilateral lower extremity lymphedema undergoing a 60-day self-management program. The study includes details of the subject's profile, the intervention, and the measurements taken with the novel tool.
The importance of cultivating awareness of environmental matters in science classrooms: a cross-regional study
Authors: Lee Ahlam 
Published: May 2023

AbstractAs scientific literacy plays a contributing role in identifying, analysing, and solving environmental matters that our world is facing, there is growing consensus to mandate environmental matters in science classrooms following five decades of efforts in promoting environmental education. However, much remains unknown about the relationship between students’ awareness of environmental matters and their science literacy scores on standardised test. Using data drawn from the 2015 Program for International Student Assessment (PISA) science performance assessment, this study investigates the relationship between students’ awareness of environmental matters and their science literacy scores in the context of established predictors for science learning. In all the regions’ multilevel models ranging from medium to large effect sizes, a significant and positive relationship emerges between students’ awareness of environmental matters and science literacy scores. Among the well-known predictors for science learning, student science self-efficacy associates positively with student science literacy scores across the regions. In contrast, inquiry-based science instruction associates negatively with the scores. Except for these two well-known predictors, variations exist in the relationships between other variables among the regions. Given all the regions’ evidence showing the positive linkage between students’ awareness of environmental matters and science literacy scores, the present study signifies the importance of integrating environmental issues into traditional science classrooms, suggesting that there should be systematic supports that enable both environmental and science educators to collaborate towards the development of an interdisciplinary environmental science curriculum.
The Impact of Digitalization on Global Trade Law
Authors: Burri Mira 
Published: May 2023

AbstractThe Article explores the transformations triggered by digitalization in the domain of global trade law and seeks to evaluate the nature and the effects of the unfolding legal adaptation in this field of international law. For this purpose, the Article starts by mapping the sweeping effects of digitalization on trade and trade policies. It then turns to the current regulatory framework for digital trade—first, by sketching the state of affairs in the multilateral forum of the World Trade Organization (WTO) and second, by analyzing the more deliberate regulatory responses to the challenge of digitalization formulated in free trade agreements (FTAs), with a particular focus on some more recent advanced models of digital trade regulation. The Article finally seeks to contextualize and assess the impact of the existing legal framework and its adequacy for the contemporary data-driven economy, pointing also at some current deficiencies and potential setbacks going forward.
Does Digitalization Change International Law Structurally?
Authors: Burchardt Dana 
Published: May 2023

AbstractThe article provides a meta-analysis of the structural impact of digitalization on international law. It synthesizes the contributions of this special issue, showing how their findings are interrelated and which cross-cutting trends we can observe. It uses an analytical framework designed to assess structural changes in international law by analyzing the impact that digitalization has on key reference points: Actors, norms, and values. From this assessment, it draws the conclusion that digitalization is changing, and will continue to change structural features of international law.
Effects of phase boundary and shear on diffusive instability
Authors: Lu Cailei , Zhang Mengqi , He Xuerao , Luo Kang , Yi Hongliang 
Published: May 2023

We study the diffusive instability subject to a solid–liquid interface and a Kolmogorov flow using modal, non-modal analyses and energy analysis. It is found that the phase boundary has different effects on the threshold of diffusive convection for weak and strong salinity stratification. In the context of oceanography where the salinity Rayleigh number RS is very high, the ice–water interface has negligible influence on the onset of diffusive convection. In the presence of shear, the diffusive convection for RS < 106 tends to be inhibited and with the increase of shear intensity, the oscillatory, steady convective and Kelvin–Helmholtz instabilities will be successively dominant. For RS > 106, the shear has a destabilizing effect on the diffusive convection, due to the generation of thermohaline-sheared instability found by Radko (J. Fluid Mech., vol. 805, 2016, pp. 147–170). Non-modal analysis indicates that for realistic parameters of high-latitude oceans, with the transition of the ultimate energy source of instability from the density gradient to background current, the thermohaline-shear instability is expected to transition from oscillatory to steady instability. The initial transient amplification due to double diffusion has also been studied, which is due to the generation of overstable instability at the initial phase. For RS < 106, the optimal initial condition to achieve the maximum transient growth favours longitudinal rolls. For thermohaline-shear instability, however, it favours transverse rolls and specifically, in oscillatory thermohaline-shear instability, the transient amplification can be enhanced by the shear by one order of magnitude, thus having important influence on the stability of the system.
Análisis tecnológicos y distribucionales de material lítico del sitio Pago Lindo (Departamento de Tacuarembó, Uruguay)
Authors: Gazzán Nicolás , Gianotti Camila , Bonomo Mariano 
Published: May 2023

ResumenEste trabajo se focaliza en el análisis espacial intrasitio del material lítico procedente de un montículo de tierra del sitio arqueológico Pago Lindo (Departamento de Tacuarembó, Uruguay). Se realizaron análisis tecnológicos y distribucionales (vecino más cercano, K de Ripley y modelos kernel) que permitieron caracterizar distintas fases de ocupación y uso del espacio entre 3021 ± 32 y 690 ± 35 años14C aP. Se reconoció una tecnología predominantemente expeditiva en la que no se observaron cambios significativos a través del tiempo. Los resultados de los análisis distribucionales muestran patrones heterogéneos que responden al uso diferencial del espacio en la estructura monticular. Los patrones agrupados, observados principalmente en microlascas, permitieron identificar sectores donde se localizaron espacios domésticos cuya ocupación y gestión de residuos contribuyó al crecimiento del montículo. También se reconocieron sectores donde las agrupaciones del material lítico tienden principalmente a la aleatoriedad, y que corresponden a episodios constructivos planificados. Esto es congruente con el modelo de crecimiento espaciotemporal discontinuo de las estructuras monticulares —basado en la alternancia de momentos de abandono y momentos de uso— pero también con episodios constructivos intencionales.
Polysomnogram outcomes in patients with laryngomalacia and obstructive sleep apnoea treated surgically versus non-surgically
Authors: Casellas Nicolas J , Shah Shalini , Ravikumar Saiganesh , Vandjelovic Nathan D , Faria John , Allen Paul D , McKenna Benoit Margo K 
Published: May 2023

AbstractObjectiveTo compare supraglottoplasty versus non-surgical treatment in children with laryngomalacia and mild, moderate and severe obstructive sleep apnoea.MethodsPatients were classified based on their obstructive apnoea hypopnoea index on initial polysomnogram, which was compared to their post-treatment polysomnogram.ResultsEighteen patients underwent supraglottoplasty, and 12 patients had non-surgical treatment. The average obstructive apnoea hypopnoea index after supraglottoplasty fell by 12.68 events per hour (p = 0.0039) in the supraglottoplasty group and 3.3 events per hour (p = 0.3) in the non-surgical treatment group. Comparison of the change in obstructive apnoea hypopnoea index in the surgical versus non-surgical groups did not meet statistical significance (p = 0.09).ConclusionAll patients with laryngomalacia and obstructive sleep apnoea had a statistically significant improvement in obstructive apnoea hypopnoea index after supraglottoplasty irrespective of obstructive sleep apnoea severity, whereas patients who received non-surgical treatment had more variable and unpredictable results. Direct comparison of the change between the two groups did not find supraglottoplasty to be superior to non-surgical treatment. Larger prospective studies are recommended.
Design, static analysis, and dynamic system modeling of 3-PPRS parallel manipulator with load-balancing UPS leg
Authors: Xavier Reni Prasad A. , Ganesh M. 
Published: May 2023

AbstractAs a heavy load is applied to the parallel manipulators, it causes inaccuracies while positioning the end-effector or unbalanced dynamic forces in the legs. Various load-balancing techniques overcome this. However, the disadvantage of most load-balancing mechanisms is that they add inertia to the assembly and decrease the speed of motion. This article studies a new load-balancing method (a passive damper mechanism). The passive balancing mechanism is proposed to negate the inertia effects while countering the static inaccuracies in the parallel mechanism. This is verified by the structural analysis of the mechanism. The impact of the damper element on the dynamics of the mechanism is unknown. Hence, a complete mathematical model for the balancing mechanism has been developed to study its impact on the dynamics of the entire structure. Laplace transformations characterize the system response. The inclusion of a passive damper in a 3-prismatic-prismatic-revolute-spherical system was examined and found to be stable and critically damped. Such a passive damper was envisaged to facilitate additional force transmission for the actuators, and the DC gain from the system response validates the torque support for the actuators.