bluuebunny/crossref_metadata_2025_split huggingface dataset:
Das Konstrukt der alltäglichen Lebenssituation
Authors: Schlüter Saskia 
Published: July 2023

ZusammenfassungIm vorliegenden Kapitel werden im Hinblick auf die Beantwortung der ersten Forschungsfrage nach den Konstruktionsfaktoren von alltäglicher Lebenssituation die theoretischen Bezugssysteme der vorliegenden Arbeit untersucht. Ziel der Untersuchung ist es, herauszuarbeiten, wie alltägliche Lebenssituation vom Subjekt konstruiert wird. Um Erkenntnisse zu gewinnen, die der Beantwortung der ersten Forschungsfrage zugrunde liegen, wird das vorliegende Kapitel wie folgt gegliedert: Zunächst erfolgt eine theoretische Auseinandersetzung mit dem Konstrukt alltägliche Lebenssituation.
Implikationen für die pädagogische Sprachdiagnostik und pädagogische Sprachförderung sowie für zukünftige Forschungsfelder auf Basis der Befunde der vorliegenden Arbeit
Authors: Schlüter Saskia 
Published: July 2023

ZusammenfassungDas vorliegende Kapitel gibt auf Basis der vorherigen Ausführungen zur Reflexion und Diskussion der Vorgehensweise und Ergebnisse der vorliegenden Arbeit einen Ausblick auf Implikationen für das Aufgabenfeld der pädagogischen Sprachdiagnostik und pädagogischen Sprachförderung. Daran anschließend werden Implikationen für zukünftige Forschungsfelder beschrieben.
Neutrinoless double beta decays tell nature of right-handed neutrinos
Authors: Asaka Takehiko , Ishida Hiroyuki , Tanaka Kazuki 
Published: July 2023

Abstract
We consider the minimal seesaw model, the Standard Model extended by two right-handed neutrinos, for explaining the neutrino masses and mixing angles measured in oscillation experiments. When one of right-handed neutrinos is lighter than the electroweak scale, it can give a sizable contribution to neutrinoless double beta (0νββ) decay. We show that the detection of the 0νββ decay by future experiments gives a significant implication to the search for such a light right-handed neutrino.
Combining transcriptomics and metabolomics to identify key response genes for aluminum toxicity in the root system of Brassica napus L. seedlings
Authors: Li Chenyang , Shi Hongsong , Xu Lu , Xing Mingli , Wu Xiaoru , Bai Yansong , Niu Mengyuan , Gao Junqi , Zhou Qingyuan , Cui Cui 
Published: July 2023

Abstract
Key Message
By integrating QTL mapping, transcriptomics and metabolomics, 138 hub genes were identified in rapeseed root response to aluminum stress and mainly involved in metabolism of lipids, carbohydrates and secondary metabolites.

Abstract
Aluminum (Al) toxicity has become one of the important abiotic stress factors in areas with acid soil, which hinders the absorption of water and nutrients by roots, and consequently retards the growth of crops. A deeper understanding of the stress-response mechanism of Brassica napus may allow us to identify the tolerance gene(s) and use this information in breeding-resistant crop varieties. In this study, a population of 138 recombinant inbred lines (RILs) was subjected to aluminum stress, and QTL (quantitative trait locus) mapping was used to preliminarily locate quantitative trait loci related to aluminum stress. Root tissues from seedlings of an aluminum-resistant (R) line and an aluminum-sensitive (S) line from the RIL population were harvested for transcriptome sequencing and metabolome determination. By combining the data on quantitative trait genes (QTGs), differentially expressed genes (DEGs), and differentially accumulated metabolites (DAMs), key candidate genes related to aluminum tolerance in rapeseed were determined. The results showed that there were 3186 QTGs in the RIL population, 14,232 DEGs and 457 DAMs in the comparison between R and S lines. Lastly, 138 hub genes were selected to have a strong positive or negative correlation with 30 important metabolites (|R|≥ 0.95). These genes were mainly involved in the metabolism of lipids, carbohydrates and secondary metabolites in response to Al toxicity stress. In summary, this study provides an effective method for screening key genes by combining QTLs, transcriptome sequencing and metabolomic analysis, but also lists key genes for exploring the molecular mechanism of Al tolerance in rapeseed seedling roots.
Predictors of outcome for treatment of enterovaginal fistula
Authors: Drefs Moritz , Schömer Cuenca Sebastian , Wirth Ulrich , Kühn Florian , Burian Maria , Werner Jens , Zimmermann Petra 
Published: July 2023

Abstract
Background
Enterovaginal fistulas represent a serious complication of various diseases and therapeutic procedures, often associated with complicated clinical courses and massive impairment of quality of life. As underlying conditions and procedures are multifarious, therapeutic approaches are challenging and have to be tailored individually. As the therapeutic management is complex and individualized, multiple surgical interventions might be necessary.

Methods
The aim of this study was to identify possible predictors for outcome in the treatment enterovaginal fistula patients. The study was realized as a retrospective analysis. Ninety-two patients treated with enterovaginal fistulas between 2004 and 2016 were analyzed. Patient characteristics, therapeutic data, and endoscopic findings were stratified according to etiology, closure rate and time, as well as recurrence of fistula. Main outcome measure was the overall rate of fistula closure.

Results
Overall therapeutic success rate was 67.4%. Postoperatively derived fistulas were most frequent (40.2%), mainly after rectal surgery (59.5%). Postoperative and non-IBD-inflammation associated fistulas had better outcome than IBD-, radiotherapy-, and tumor-related fistulas (p = 0.001). Successful fistula closure was observed more frequently after radical surgical interventions, best results observed after transabdominal surgery (p < 0.001). Fistula recurrence was also less frequently observed after radical surgical therapies (p = 0.029). A temporary stoma was associated with higher incidence of fistula closure (p = 0.013) and lower incidence of fistula recurrence (p = 0.042) in the postoperative subgroup, as well as shortened therapy period in all groups (p = 0.031).

Conclusion
Enterovaginal fistulas are a result of various etiologies, and treatment should be adjusted accordingly. A very sustainable, rapid, and persistent therapeutic success can be expected after radical surgical approaches with temporary diverting stoma. This is especially true for postoperatively derived fistulas.
Retrospective clinical and X-ray-based outcome analysis of a short-stem hip arthroplasty taking into account the operative learning curve over 7 years in the 3-year control course
Authors: Jahnke Alexander , Köther-Herrmann Jan , Fonseca Ulloa Carlos A. , Harz Torben , Rickert Markus , Ishaque Bernd Alexander 
Published: July 2023

Abstract
Introduction
Self-monitoring is crucial to work progressively with a high-quality standard. A retrospective analysis is a valuable tool for studying the postoperative outcome of a prosthesis and for evaluating the learning process for the surgeon.

Materials and methods
The learning process of one surgeon was analysed in 133 cases of hip arthroplasty. These were divided into seven groups representing the surgical years 2008–2014. Over the course of 3 postoperative years, a total of 655 radiographs were analysed at regarding three radiological quality parameters (centrum-collum-diaphyseal angle (CCD angle), intramedullary fit&fill ratio (FFR), and migration) and ancillary outcome parameters (Harris Hip Score (HHS), blood loss, operating time, and complications). This period was divided into five times: 1st-day post-op, 6 M, 12 M, 24 M, and 36 M. Bivariate Spearman's correlation analysis and pairwise comparisons were performed.

Results
The total collective achieved a proximal FFR of over 0.8. The distal prosthesis tip migrated and was located on the lateral cortex within the first months. The CCD angle initially showed a variation with a subsequent constant course. The HHS showed a significant increase (p < 0.001) to over 90 points postoperatively. Over time, the operating time and blood loss decreased. Intraoperative complications existed only at the beginning of the learning phase. A learning curve effect can be determined for almost all parameters by comparing the subject groups.

Conclusions
Operative expertise was shown to gain through a learning curve, whereby postoperative results corresponded to the system philosophy of the short hip stem prosthesis. The distal FFR and the distal lateral distance could represent the principle of the prosthesis, which overall could be an interesting approach for verification of a new parameter.
Validated method for polystyrene nanoplastic separation in aqueous matrices by asymmetric-flow field flow fraction coupled to MALS and UV–Vis detectors
Authors: H.Valido Iris , Fuentes-Cebrian Victor , Hernández Alba , Valiente Manuel , López-Mesas Montserrat 
Published: July 2023

AbstractPlastics with nanosize (nanoplastics, NPLs) must be characterized, since they can be toxic or act as carriers of organic and inorganic pollutants, but there is a lack of reference materials and validated methods in the nanosize range. Therefore, this study has focused on the development and validation of a separation and size characterization methodology of polystyrene latex nanospheres, by using an asymmetric-flow field flow fraction system coupled to multi-angle light scattering and ultraviolet–visible detectors (AF4-MALS-UV). Hence, this work presents a fully validated methodology in the particle size range 30 to 490 nm, with bias between 95 and 109%, precision between 1 and 18%, LOD and LOQ below 0.2 and 0.3 µg respectively, except for 30-nm standard, for both detectors, and showing stable results for 100 analyses.
Graphical Abstract
Callose deposition analysis with special emphasis on plasmodesmata ultrastructure during megasporogenesis in Sedum (Crassulaceae)
Authors: Brzezicka Emilia , Kozieradzka-Kiszkurno Małgorzata 
Published: July 2023

AbstractIn this study, the results of the first detection of callose within the ovules of the representatives of the family Crassulaceae are presented. This study was carried out on three species of the genus Sedum. Data analysis showed differences in the callose deposition pattern between Sedum hispanicum and Sedum ser. Rupestria species during megasporogenesis. Callose was present mostly in the transversal walls of dyads and tetrads in S. hispanicum. Furthermore, a complete loss of callose from the cell walls of the linear tetrad and a gradual and simultaneous deposition of callose within the nucellus of S. hispanicum were observed. The findings of this study showed the presence of hypostase with callose in the ovules of S. hispanicum, which is not common in other angiosperms. The remaining species tested in this study—Sedum sediforme and Sedum rupestre—showed a typical, well-known callose deposition pattern for plants with the monospore type of megasporogenesis and the Polygonum type of embryo sac. The functional megaspore (FM) in all studied species was located most chalazally. FM is a mononuclear cell, which wall is callose-free in the chalazal pole. The study presents the causes of different patterns of callose deposition within Sedum and their relationship with the systematic position of the study species. Moreover, embryological studies present an argument for excluding callose as a substance that forms an electron-dense material near the plasmodesmata in megaspores of S. hispanicum. This research expands the knowledge about the embryological processes of succulent plants from the family Crassulaceae.
Quality of life and healthcare costs of patients with allergic respiratory diseases: a cross-sectional study
Authors: Hillerich Vivienne , Valbert Frederik , Neusser Silke , Pfaar Oliver , Klimek Ludger , Sperl Annette , Werfel Thomas , Hamelmann Eckard , Riederer Cordula , Wobbe-Ribinski Stefanie , Neumann Anja , Wasem Jürgen , Biermann-Stallwitz Janine 
Published: July 2023

Abstract
Background
Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality of Life (HRQoL) of the patients in order to identify statistically significant influencing factors that determine HRQoL. Another aim was to assess and analyze data on cost-of-illness from a statutory health insurance perspective.

Methods
The EQ-5D-5L was used to evaluate the patients’ HRQoL. To identify the factors influencing the HRQoL, a multinomial logistic regression analysis was conducted using groups based on the EQ-5D-5L index value as dependent variable. Routine data were analyzed to determine total healthcare costs.

Results
The average EQ-5D-5L index was 0.85 (SD 0.20). A high age, the amount of disease costs, low internal health-related control beliefs and high ozone exposure in the residential area were found to be statistically significant influencing factors for a low HRQoL, whereas low age, male sex and a good possibility to avoid the allergens were found to be statistically significant factors influencing a high HRQoL. On average, the study participants incurred annual costs of €3072 (SD: 3485), of which €699 (SD: 743) could be assigned to allergic respiratory diseases.

Conclusions
Overall, the patients in the VerSITA study showed a high level of HRQoL. The identified influencing factors can be used as starting points for improving the HRQoL of patients with allergic respiratory diseases. From the perspective of a statutory health insurance, per person expenditures for allergic respiratory diseases are rather low.
University students’ beliefs about science and their relationship with knowledge about science
Authors: Schoor Cornelia 
Published: July 2023

AbstractScience and personal experiences in some cases seem to be two different ways of knowledge justification. The current “post-truth” era is characterized by a rise of personal beliefs and justifications. In order to address these phenomena from a perspective of beliefs, several constructs may be considered: Beliefs about the utility of science and of personal experiences, trust in science, and epistemic beliefs. Despite some research addressing each belief’s independent relation to information seeking behavior, we do not know much about the interrelationship of these beliefs. To address this research gap and to explore whether knowledge about how science works is related to these beliefs, a paper–pencil study with 315 university students of psychology, education, and teacher education was conducted. There was a high positive relationship of trust in science with justification-by-authority beliefs, and medium negative relationships of trust in science with uncertainty beliefs and personal-justification beliefs. Trust in science was positively related to the perceived utility of science. Epistemic beliefs were also related to utility beliefs. The number of methods courses taken and knowledge about how science works was related to trust in science and epistemic beliefs, but not to utility of science or utility of personal experiences. It is concluded that we should revisit our conceptualization of epistemic beliefs in the context of “post-truth”.
Cavity-breeding birds create specific microhabitats for diverse arthropod communities in boreal forests
Authors: Hanzelka Jan , Baroni Daniele , Martikainen Petri , Eeva Tapio , Laaksonen Toni 
Published: July 2023

AbstractThe nests of secondary cavity-nesters located in tree cavities may form specific microhabitats of conservation importance due to their limited accessibility and availability. Species-specific nesting materials in nests of different secondary cavity-nesters may furthermore provide very different microhabitats for arthropods. The potential differences in arthropod communities inhabiting nests of different bird species in excavated cavities or nest boxes have, however, rarely been studied despite their relevance for conservation. Here we investigated the diversity and composition of arthropod communities in these different cavity types and bird species’ nests in managed boreal forests. We identified morphologically and by DNA-metabarcoding arthropods in nest materials that were collected in and compared between (i) woodpecker-size cavities from seven different combinations of cavity type (nest box or excavated cavity), tree species (aspen or pine) and accumulation history of nest materials (single-season cleaned or uncleaned nest boxes that accumulated nests of passerines or an owl species); and (ii) nests of two different passerine species in small nest boxes. We identified 64 arthropod taxa in ten orders, from which Diptera, Coleoptera, Siphonaptera, and Lepidoptera were the most abundant. Shannon diversity index was similar among the cavity-nest-type combinations, but taxa richness was the highest in the owl nests. The arthropod communities (especially Histeridae beetles) deviated most from the other types of nests in owl and aspen cavity nests with more advanced decomposition of nest material (soil or wet environment related taxa). The differences in arthropod communities between the different nest types point out the importance of the ecological chain “tree cavities—bird nests—arthropod communities”.
Exposure to pesticides and risk of Hodgkin lymphoma in an international consortium of agricultural cohorts (AGRICOH)
Authors: Kim Joanne , Leon Maria E. , Schinasi Leah H. , Baldi Isabelle , Lebailly Pierre , Freeman Laura E. Beane , Nordby Karl-Christian , Ferro Gilles , Monnereau Alain , Brouwer Maartje , Kjaerheim Kristina , Hofmann Jonathan N. , Straif Kurt , Kromhout Hans , Schüz Joachim , Togawa Kayo 
Published: July 2023

AbstractPurposeSome pesticides may increase the risk of certain lymphoid malignancies, but few studies have examined Hodgkin lymphoma (HL). In this exploratory study, we examined associations between agricultural use of 22 individual active ingredients and 13 chemical groups and HL incidence.MethodsWe used data from three agricultural cohorts participating in the AGRICOH consortium: the French Agriculture and Cancer Cohort (2005–2009), Cancer in the Norwegian Agricultural Population (1993–2011), and the US Agricultural Health Study (1993–2011). Lifetime pesticide use was estimated from crop-exposure matrices or self-report. Cohort-specific covariate-adjusted overall and age-specific (< 40 or ≥ 40 years) hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression and combined using random effects meta-analysis.ResultsAmong 316 270 farmers (75% male) accumulating 3 574 815 person-years at risk, 91 incident cases of HL occurred. We did not observe statistically significant associations for any of the active ingredients or chemical groups studied. The highest risks of HL overall were observed for the pyrethroids deltamethrin (meta-HR = 1.86, 95% CI 0.76–4.52) and esfenvalerate (1.86, 0.78–4.43), and inverse associations of similar magnitude were observed for parathion and glyphosate. Risk of HL at ≥ 40 years of age was highest for ever-use of dicamba (2.04, 0.93–4.50) and lowest for glyphosate (0.46, 0.20–1.07).ConclusionWe report the largest prospective investigation of these associations. Nonetheless, low statistical power, a mixture of histological subtypes and a lack of information on tumour EBV status complicate the interpretability of the results. Most HL cases occurred at older ages, thus we could not explore associations with adolescent or young adult HL. Furthermore, estimates may be attenuated due to non-differential exposure misclassification. Future work should aim to extend follow-up and refine both exposure and outcome classification.
Insights into the borohydride reduction of dialdehyde cellulose: the dilemma of competing reduction and β-elimination reactions
Authors: Simon Jonas , Fliri Lukas , Fröhlich Flavia , Sapkota Janak , Ristolainen Matti , Hummel Michael , Rosenau Thomas , Potthast Antje 
Published: July 2023

AbstractBorohydride reduction of dialdehyde cellulose (DAC) is a promising strategy to generate dialcohol cellulose as bio-based alternative to petroleum-based materials. However, the degradation of the polymer backbone according to β-elimination mechanisms limits the practical applications of the reaction. Therefore, we aimed at optimizing the process to suppress degradation reactions by varying reaction time, pH, and reagent stoichiometry. The degree of oxidation (DO) of the DAC intermediates significantly impacts the yields and molecular weights of the isolated dialcohol celluloses, with a “leveling-off” effect at higher DO values. Increasing the amount of sodium borohydride can minimize—but not entirely prevent—chain scissions. Lowering the pH value during reduction slows down the degradation but results in incomplete conversion of the aldehyde functionalities. Our study provides valuable insights into the consequences of side reactions during borohydride reduction of DAC as well as into chemistry and analysis of the dialdehyde cellulose/dialcohol cellulose system.Graphical abstractAbout a dilemma in cellulose chemistry: Dialcohol cellulose derived by periodate oxidation and subsequent borohydride reduction of cellulose has received increasing attention in the development of sustainable thermoplastic materials. The present study highlights the challenge of suppressing β-elimination and favoring the reduction pathway to optimize reaction conditions and minimize chain degradation.
A compactification of the moduli space of multiple-spin curves
Authors: Sertöz Emre Can 
Published: July 2023

AbstractWe construct a smooth Deligne–Mumford compactification for the moduli space of curves with an m-tuple of spin structures using line bundles on quasi-stable curves as limiting objects, as opposed to line bundles on stacky curves. For all m, we give a combinatorial description of the local structure of the corresponding coarse moduli spaces. We also classify all irreducible and connected components of the resulting moduli spaces of multiple-spin curves.
Solubility of Salicylic Acid in Some (Ethanol + Water) Mixtures at Different Temperatures: Determination, Correlation, Thermodynamics and Preferential Solvation
Authors: Akay Sema , Kayan Berkant , Peña María Ángeles , Jouyban Abolghasem , Martínez Fleming 
Published: July 2023

AbstractEquilibrium mole fraction solubility of salicylic acid in nine aqueous-ethanolic mixtures, as well as in neat water and neat ethanol, was determined at seven temperatures from T = (293.15 to 323.15) K. Salicylic acid solubility in these mixtures was adequately correlated with well-known correlation/prediction methods based on Jouyban-Acree model. Apparent thermodynamic quantities, i.e. Gibbs energy, enthalpy, and entropy, for the dissolution and mixing processes, were computed by means of the van’t Hoff and Gibbs equations. The enthalpy–entropy compensation plot of enthalpy vs. Gibbs energy of dissolution was not linear exhibiting positive slopes from neat water to the mixture of w1 = 0.30 and from the mixture of w1 = 0.50 to neat ethanol indicating enthalpy-driven drug transfer processes but negative in the interval of 0.30 < w1 < 0.50 indicating entropy-driven drug transfer processes from more polar to less polar solvent systems. Moreover, by using the inverse Kirkwood–Buff integrals it is observed that salicylic acid is preferentially solvated by water molecules in water-rich mixtures but preferentially solvated by ethanol molecules in those mixtures of 0.24 < x1 < 1.00.