bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Space between Look and Read
Authors: Hagan Susan M. 
Published: March 2023

Unleashing the potential that can be found in the space between words and images.
Designers have long understood that image, text, and typeface can work together to produce new meanings, creating semiotic registers impossible to achieve with image or text alone. In The Space Between Look and Read, a study of complementary meaning in design, Susan Hagan presents a framework, called Inter-play, which explains how these new meanings emerge. Inter-play is not simply an analytical tool; it is also a method for using complementary meaning to encourage critical thinking in design audiences.
Drawing from cognitive psychology, art theory, discourse analysis, design, and rhetoric, Hagan breaks down the synthesis of looking and reading into a complex series of registers, which are revealed through examples of excellent design. Thus, the book is both a theoretical exploration of how designers communicate and a casebook in communication well achieved.
From the physiology of vision to the limits of language, from Allan Paivio to Uwe Loesch, The Space Between Look and Read expands our understanding of complementary design and argues that by engaging audiences through multiple cognitive registers, complementary design serves as a cognitive tool, helping audiences reach new conclusions about complex problems.
Off-Earth
Authors: Nesvold Erika 
Published: March 2023

Can we do better in space than we've done here on Earth?
We've pinpointed the destination, refined the technology, designed the habitat, outfitted our space residents. Are we forgetting something? A timely reminder that it's not just rocket science, this thought-provoking book explores the all-too-human issues raised by the prospect of settling in outer space. It's worth remembering, Erika Nesvold suggests, that in making new worlds, we don't necessarily leave our earthly problems behind. Accordingly, her work highlights the complex ethical challenges that accompany any other-worldly venture—questions about the environment, labor rights, and medical ethics, among others.
Any such venture, Nesvold contends, must be made on behalf of all humanity, with global input and collaboration. Off-Earth thus includes historical and contemporary examples from outside the dominant Western/US, abled, and privileged narrative of the space industry. Nesvold calls on experts in ethics, sociology, history, social justice, and law to launch a hopeful conversation about the potential ethical pitfalls of becoming a multi-planet species—and, ideally, to shed light on similar problems we presently face here on Earth.
Space settlement is rapidly becoming ever more likely. Will it look like the utopian vision of Star Trek? Or the dark future of Star Wars? Nesvold challenges us to decide.
Constructing Student Mobility
Authors: Kim Stephanie K. 
Published: March 2023

How universities in the US and South Korea compete for global student markets—and how university financials shape students' lives.
The popular image of the international student in the American imagination is one of affluence, access, and privilege, but is that image accurate? In this provocative book, higher education scholar Stephanie Kim challenges this view, arguing that universities -- not the students -- create the paths that allow students their international mobility. Focusing on universities in the United States and South Korea that aggressively grew their student pools in the aftermath of the Great Recession, Kim shows the lengths to which universities will go to expand enrollments as they draw from the same pool of top South Korean students.
Kim closely follows several students attending a university in Berkeley and a university in Seoul. They have chosen different paths to study abroad or learn at home, but all are seeking a transformative educational experience. To show how student mobility depends on institutional structures, Kim demonstrates how the universities themselves compel students' choices to pursue higher learning at one institution or another. She also profiles the people who help ensure the global student supply chain runs smoothly, from education agents in South Korea to community college recruiters in California. Using ethnographic research gathered over a ten-year period in which international admissions were impacted by the Great Recession, changes in US presidential administrations, and the COVID-19 pandemic, Constructing Student Mobility provides crucial insights into the purpose, effects, and future of student recruitment across the Pacific.
¡Alerta!
Authors: Reddy Elizabeth 
Published: March 2023

A lively account of a controversial technology developed to mitigate earthquake risk and change how we live with threatening environments.
The Sistema de Alerta Sísmica Mexicano is the world's oldest public earthquake early warning system. Given the unpredictability of earthquakes, the technology was designed to give the people of Mexico City more than a minute to prepare before the next big quake hits. How does this kind of environmental monitoring technology get built in the first place? How does its life-saving promise align with reality? And who shapes modern risk mitigation? In ¡Alerta!, Elizabeth Reddy surveys this innovation to shed light on what it means to imagine a world where sirens could sound out an ¡alerta sísmica! at any moment—and what it would be like to live in such a world.
Proponents of earthquake early warnings havelong held that the technology can save lives and limit economic losses. Drawing on ethnographic fieldwork and archival data, Reddy conducts a thorough, qualitative analysis of these claims and considers the requirements and uses of the alert system. She embeds her study in a rich narrative of the engineers who designed the system in conjunction with contingent political and environmental conditions. The result demonstrates how addressing earthquake dangers is no small task: it means trying to change relationships between the environment, society, and technology. Doing so, she critiques universalist and techno-centric approaches to hazard risk mitigation and celebrates the potential of contextually appropriate and broadly supported efforts.
¡Alerta! takes readers on a vivid journey into the world of Mexican earthquake risk mitigation, with critical insights for anthropologists and science and technology studies scholars, as well as specialists in the geosciences, engineering, and emergency management.
Media Ruins
Authors: Jack Margaret 
Published: March 2023

How a generation of tech-savvy young Cambodians is restoring historical media artifacts from before the war—and, in the process, helping to repair the Khmer Rouge's cultural destruction.
During the Khmer Rouge regime (1975–1979), an estimated quarter to a third of the Cambodian population perished from execution, starvation, or disease. The regime especially targeted artists and intellectuals and their work, including films, photographs, and audio recordings. In Media Ruins, Margaret Jackcharts the critical role of media in the historical political landscape of Cambodia as well as in its post-conflict reconstruction and reconciliation. Along the way, Jack tells the remarkable stories of resourceful Cambodians in the decades that followed the end of the regime—those who worked to reconstruct their country's media infrastructure and restore their damaged cultural heritage.
Jack describes the crucial role that media has played in helping the nation grapple with the traumas of its past and imagine brighter futures. She explores how tech-savvy Cambodian media creators have engaged in practices of infrastructural restitution—work that is both emotionally cathartic and politically vital. She also examines the ways these media creators have used digital tools to restore and disseminate lost media artifacts, while embracing an aesthetic of material decay as a visible reminder of loss. As these creators reconcile with the past, they are also finding ways to navigate the country's increasingly authoritarian media landscape. Bringing media and technology studies into conversation with trauma and memory studies, the book provides a unique, and necessary, perspective on post-conflict reconstruction.
Living with Algorithms
Authors: Siles Ignacio 
Published: March 2023

A nuanced account from a user perspective of what it's like to live in a datafied world.
We live in a media-saturated society that increasingly transforms our experiences, relations, and identities into data others can analyze and monetize. Algorithms are key to this process, surveilling our most mundane practices, and to many, their control over our lives seems absolute. In Living with Algorithms, Ignacio Siles critically challenges this view by surveying user dynamics in the global south across three algorithmic platforms—Netflix, Spotify, and TikTok—and finds, surprisingly, a more balanced relationship.
Drawing on a wealth of empirical evidence that privileges the user over the corporate, Siles examines the personal relationships that have formed between users and algorithms as Latin Americans have integrated these systems into the structures of everyday life, enacted them ritually, participated in public with and through them, and thwarted them. Sometimes users follow algorithms, Siles finds, and sometimes users resist them. At times, users do both. Agency lies in the navigation of the spaces in-between.
By analyzing what we do with algorithms rather than what algorithms do to us, Living with Algorithms clarifies the debate over the future of datafication and whether we have a say in its development. Concentrating on an understudied region of the global south, the book provides a new perspective on the commonalities and differences among users within a global ecology of technologies.
Genome-wide survey of HMA gene family and its characterization in wheat (Triticum aestivum)
Authors: Zahra Sadaf , Shaheen Tayyaba , Qasim Muhammad , Mahmood-ur-Rahman  , Hussain Momina , Zulfiqar Sana , Shaukat Kanval , Mehboob-ur-Rahman  
Published: March 2023

Background
Abiotic stresses, particularly drought and heavy metal toxicity, have presented a significant risk to long-term agricultural output around the world. Although the heavy-metal-associated domain (HMA) gene family has been widely explored in Arabidopsis and other plants, it has not been thoroughly studied in wheat (Triticum aestivum). This study was proposed to investigate the HMA gene family in wheat.

Methods
To analyze the phylogenetic relationships, gene structure, gene ontology, and conserved motifs, a comparative study of wheat HMA genes with the Arabidopsis genome was performed.

Results
A total of 27 T. aestivum proteins belonging to the HMA gene family were identified in this study, with amino acid counts ranging from 262 to 1,071. HMA proteins were found to be grouped into three subgroups in a phylogenetic tree, and closely related proteins in the tree showed the same expression patterns as motifs found in distinct subgroups. Gene structural study elucidated that intron and exon arrangement differed by family.

Conclusion
As a result, the current work offered important information regarding HMA family genes in the T. aestivum genome, which will be valuable in understanding their putative functions in other wheat species.
Long-term outcomes and predictors of patients with ST elevated versus non-ST elevated myocardial infarctions in non-obstructive coronary arteries: a retrospective study in Northern China
Authors: Chen Lin , Fan Yinghong , Fang Zhen , Liu Ning 
Published: March 2023

Background
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous disease entity with diverse etiologies and no uniform treatment protocols. Patients with MINOCA can be clinically classified into two groups based on whether they have an ST-segment elevation (STE) or non-ST segment elevation (NSTE), based on electrocardiogram (ECG) results, whose clinical prognosis is unclear. This study aimed to compare the outcomes and predictors of patients with STE and NSTE in the MINOCA population.

Methods
We collected the data for 196 patients with MINOCA (115 with STE and 81 with NSTE) in China. Clinical characteristics, prognoses, and predictors of major adverse cardiovascular events (MACE) were analyzed during the follow-up of all patients.

Results
The proportion of patients with STE was greater than that with NSTE in the MINOCA population. Patients with NSTE were older and had a higher incidence of hypertension. No differences were observed in the outcomes between the STE and NSTE groups during a median follow-up period of 49 (37,46) months. No significant differences were observed in those with MACE (24.35% vs 22.22%, P = 0.73) and those without MACE. The multivariable predictors of MACE in the NSTE groups were Killip grades ≥ 2 (HR 9.035, CI 95% [1.657–49.263], P = 0.011), reduced use of β-blockers during hospitalization (HR 0.238, CI 95% [0.072–0.788], P = 0.019), and higher levels of low-density lipoprotein cholesterol (LDL-C) (HR 2.267, CI 95% [1.008–5.097], P = 0.048); the reduced use of β-blockers during hospitalization was the only independent risk factor of MACE in the STE group.

Conclusions
There were differences between the clinical characteristics of patients with STE and NSTE in the MINOCA population, even though outcomes during follow-up were similar. Independent risk factors for major adverse cardiac events were not identical in the STE and NSTE groups, which could be attributable to the differences in disease pathogenesis.
Association of BRAF Variants With Disease Characteristics, Prognosis, and Targeted Therapy Response in Intrahepatic Cholangiocarcinoma
Authors: Xin Hao-Yang , Sun Rong-Qi , Zou Ji-Xue , Wang Peng-Cheng , Wang Jia-Yin , Ye Yu-Hang , Liu Kai-Xuan , Hu Zhi-Qiang , Zhou Zheng-Jun , Fan Jia , Zhou Jian , Zhou Shao-Lai 
Published: March 2023

ImportanceBRAF variants are associated with tumor progression; however, the prevalence of BRAF variant subtypes and their association with disease characteristics, prognosis, and targeted therapy response in patients with intrahepatic cholangiocarcinoma (ICC) are largely unknown.ObjectiveTo explore the association of BRAF variant subtypes with disease characteristics, prognosis, and targeted therapy response in patients with ICC.Design, Setting, and ParticipantsIn this cohort study, 1175 patients who underwent curative resection for ICC from January 1, 2009, through December 31, 2017, were evaluated at a single hospital in China. Whole-exome sequencing, targeted sequencing, and Sanger sequencing were performed to identify BRAF variants. The Kaplan-Meier method and log-rank test were used to compare overall survival (OS) and disease-free survival (DFS). Univariate and multivariate analyses were performed using Cox proportional hazards regression. Associations between BRAF variants and targeted therapy response were tested in 6 BRAF-variant, patient-derived organoid lines and in 3 of the patient donors of those lines. Data were analyzed from June 1, 2021, to March 15, 2022.InterventionsHepatectomy in patients with ICC.Main Outcomes and MeasuresThe association of BRAF variant subtypes with OS and DFS.ResultsOf 1175 patients with ICC, the mean (SD) age was 59.4 (10.4) years and 701 (59.7%) were men. A total of 20 different subtypes of BRAF somatic variance affecting 49 patients (4.2%) were identified; V600E was the most frequent allele in this cohort, accounting for 27% of the identified BRAF variants, followed by K601E (14%), D594G (12%), and N581S (6%). Compared with patients with non-V600E BRAF variants, patients with BRAF V600E variants were more likely to have large tumor size (10 of 13 [77%] vs 12 of 36 [33%]; P = .007), multiple tumors (7 of 13 [54%] vs 8 of 36 [22%]; P = .04), and more vascular/bile duct invasion (7 of 13 [54%] vs 8 of 36 [22%]; P = .04). Multivariate analysis revealed that BRAF V600E variants, but not overall BRAF variants or non-V600E BRAF variants, were associated with poor OS (hazard ratio [HR], 1.87; 95% CI, 1.05-3.33; P = .03) and DFS (HR, 1.66; 95% CI, 1.03-2.97; P = .04). There were also broad differences among organoids with different BRAF variant subtypes in sensitivity to BRAF or MEK inhibitors.Conclusions and RelevanceThe findings of this cohort study suggest that there are broad differences among organoids with different BRAF variant subtypes in sensitivity to BRAF or MEK inhibitors. Identifying and classifying BRAF variants may be able to help guide precise treatment for patients with ICC.
Coherence of child maltreatment narratives by emerging adults: How does child maltreatment affect how we share our story?
Authors: Fishere Mariam , Habermas Tilmann 
Published: March 2023

AbstractIndividuals narrate stories to explain how they became who they are, forming their own narrative identity. Highly disruptive experiences such as child maltreatment (CM) may be challenging to integrate into the life story and even to narrate coherently just by themselves. To test these potential effects, we divided a total of 171 students at an English‐speaking university in Egypt into two groups, those with a history of CM and those who experienced none. We compared narratives of four different types of emotional childhood experiences. Narratives of CM were no less coherent than narratives of most stressful childhood experiences in the control group, but were more integrated into the life story, which in turn predicted symptoms of posttraumatic stress disorder (PTSD). The present study contributes to the literature by confirming that there is no evidence for a lack of coherence among adults' CM narratives, and by highlighting the association between the centrality of the traumatic event in one's life and PTSD symptoms.
Building Highly Light‐Harvesting Near‐Infrared AIEgens Using Triazole‐Based Luminescent Core for Improved Intravital Afterglow Imaging
Authors: Li Jisen , Zhang Guo‐Qiang , Zhang Yufan , Tang Youhong , Ding Dan , Li Wen , Liu Qian 
Published: March 2023

AbstractDevelopment of the powerful building block is of great significance to construct materials with advanced properties. Herein, for the first time, a triazole‐based luminescent core with balanced twist and conjugation is reported, which is explored to construct a D‐A near‐infrared (NIR) aggregation‐induced emission luminogens (TPT‐DCM) with high molar extinction coefficient, good brightness and excellent reactive oxygen species generation rate. These features enable it to function as a nanoprobe with ultralong NIR afterglow luminescence (up to 20 days) and ultrahigh tumor‐to‐liver signal ratio (up to 187) for in vivo deep‐tissue afterglow imaging (with depth reaching 1.6 cm), in combination with chemiluminescence resonance energy transfer aided by active Schaap's dioxetane. Moreover, thanks to the excellent properties of the nanoprobe, the afterglow imaging‐guided surgery navigation can be successfully conduced to remove the tumors especially with tiny size of < 1 mm. This is particularly useful to eliminate tumor residuals and prevent the cancer recurrence after surgery.
Low‐Valent Manganese Atoms Stabilized on Ceria for Nitrous Oxide Synthesis
Authors: Surin Ivan , Tang Zhenchen , Geiger Julian , Damir Suyash , Eliasson Henrik , Agrachev Mikhail , Krumeich Frank , Mitchell Sharon , Kondratenko Vita A. , Kondratenko Evgenii V. , Jeschke Gunnar , Erni Rolf , López Núria , Pérez‐Ramírez Javier 
Published: March 2023

AbstractNitrous oxide, N2O, exhibits unique reactivity in oxidation catalysis, but the high manufacturing costs limit its prospective uses. Direct oxidation of ammonia, NH3, to N2O can ameliorate this issue but its implementation is thwarted by suboptimal catalyst selectivity and stability, and the lack of established structure–performance relationships. Systematic and controlled material nanostructuring offers an innovative approach for advancement in catalyst design. Herein low‐valent manganese atoms stabilized on ceria, CeO2, are discovered as the first stable catalyst for NH3 oxidation to N2O, exhibiting two‐fold higher productivity than the state‐of‐the‐art. Detailed mechanistic, computational and kinetic studies reveal CeO2 as the mediator of oxygen supply, while undercoordinated manganese species activate O2 and facilitate N2O evolution via NN bond formation between nitroxyl, HNO, intermediates. Synthesis via simple impregnation of a small metal quantity (1 wt%) predominantly generates isolated manganese sites, while full atomic dispersion is achieved upon redispersion of sporadic oxide nanoparticles during reaction, as confirmed by advanced microscopic analysis and electron paramagnetic resonance spectroscopy. Subsequently, manganese speciation is maintained, and no deactivation is observed over 70 h on stream. CeO2‐supported isolated transition metals emerge as a novel class of materials for N2O production, encouraging future studies to evaluate their potential in selective catalytic oxidations at large.
PIP2 Alteration Caused by Elastic Modulus and Tropism of Electrospun Scaffolds Facilitates Altered BMSCs Proliferation and Differentiation
Authors: Gao Chen , Lai Yulin , Cheng Liang , Cheng Yifan , Miao Anqi , Chen Jialong , Yang Runhuai , Xiong Fei 
Published: March 2023

AbstractAligned submicron fibers have played an essential role in inducing stem cell proliferation and differentiation. In this study, it is aimed to identify the differential causes of stem cell proliferation and differentiation between bone marrow mesenchymal stem cells (BMSCs) on aligned‐random fibers with different elastic modulus, and to change the differential levels through a regulatory mechanism mediated by B‐cell lymphoma 6 protein(BCL‐6) and miRNA‐126‐5p(miR‐126‐5p). The results showed that phosphatidylinositol(4,5)bisphosphate alterations are found in the aligned fibers compared with the random fibers, which has a regular and oriented structure, excellent cytocompatibility, regular cytoskeleton, and high differentiation potential. The same trend is actual for the aligned fibers with a lower elastic modulus. The level of proliferative differentiation genes in cells is altered by BCL‐6 and miR‐126‐5p mediated regulatory mechanisms to make the cell distribution nearly consistent with the cell state on low elastic modulus aligned fibers. This work demonstrates the reason for the difference of cells between the two kinds of fibers and on fibers with different elastic modulus. These findings provide more insights for understanding the gene‐level regulation of cell growth in tissue engineering.