bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influencing factors of medication literacy among community-dwelling older adult patients with hypertension: a study based on social learning theory
Authors: Lu Tingting , Yang Zhen , Chen Ping , Li Jingyan , Zheng Chen , Kong Linghui , Zhang Huijun 
Published: June 2023

Objective: This study aimed to examine the factors affecting medication literacy in community-dwelling older adults with hypertension, guided by social learning theory. It sought to analyze the pathways these factors influenced and provide a theoretical foundation for designing targeted intervention programs.Study design: This is a cross-sectional study.Methods: From October 2022 to February 2023, a total of 432 community-dwelling older adults with hypertension from Linghe District, Guta District, and Taihe District, Jinzhou City, Liaoning Province, China, were selected using convenience sampling. Data were collected using a socio-demographic questionnaire, a medication literacy questionnaire, the Brief Illness Perception Questionnaire, the General Self-efficacy Scale, and the Perceived Social Support Scale. The collected data were analyzed with Kruskal-Wallis and Mann-Whitney tests, correlation analysis, multiple stepwise regression analysis, and structural equation modeling (SEM).Results: The medication literacy score among the participants was 3.83 ± 1.91. Multi-factor analysis revealed key factors affecting their medication literacy, including blood pressure-control status, utilization of community health education resources, receiving guidance for medication usage, marital status, number of annual visits, social support, self-efficacy, and disease perception. The SEM based on social learning theory showed that general self-efficacy mediated the relationship between social support, disease perception, and medication literacy.Conclusion: The present study developed a model and provided potential intervention strategies to improve medication literacy, knowledge, and safety among community-dwelling older adults with hypertension, considering the relationships between the identified variables.
Recent advances of exosomes in age-related macular degeneration
Authors: Gu Feng , Jiang Jiyu , Sun Peng 
Published: June 2023

Exosomes are 30–150 nm extracellular vesicles that are secreted by almost all types of cells. Exosomes contain a variety of biologically active substances, such as proteins, nucleic acids, and lipids, and are important in the intercellular communication of biological mediators involved in nerve injury and repair, vascular regeneration, immune response, fibrosis formation, and many other pathophysiological processes. Although it has been extensively studied in the field of cancer, the exploration of ocular diseases has only just begun. Here, we discuss the latest developments in exosomes for age-related macular degeneration (AMD), including the pathogenesis of exosomes in age-related macular degeneration, their potential as diagnostic markers, and therapeutic vectors of the disease. Finally, the study of exosomes in age-related macular degeneration is still relatively few, and more detailed basic research and clinical trials are needed to verify its application in treatment and diagnosis, so as to adopt more personalized diagnosis and treatment strategies to stop the progression of age-related macular degeneration.
Neuromuscular adjustments to unweighted running: the increase in hamstring activity is sensitive to trait anxiety
Authors: Fazzari Camille , Macchi Robin , Ressam Camélia , Kunimasa Yoko , Nicol Caroline , Martha Cécile , Bolmont Benoît , Sainton Patrick , Hays Arnaud , Vercruyssen Fabrice , Lapole Thomas , Bossard Martin , Casanova Rémy , Bringoux Lionel , Chavet Pascale 
Published: June 2023

Introduction: Originally developed for astronauts, lower body positive pressure treadmills (LBPPTs) are increasingly being used in sports and clinical settings because they allow for unweighted running. However, the neuromuscular adjustments to unweighted running remain understudied. They would be limited for certain lower limb muscles and interindividually variable. This study investigated whether this might be related to familiarization and/or trait anxiety.Methods: Forty healthy male runners were divided into two equal groups with contrasting levels of trait anxiety (high, ANX+, n = 20 vs. low, ANX−, n = 20). They completed two 9-min runs on a LBPPT. Each included three consecutive 3-min conditions performed at 100%, 60% (unweighted running), and 100% body weight. Normal ground reaction force and electromyographic activity of 11 ipsilateral lower limb muscles were analyzed for the last 30 s of each condition in both runs.Results: Unweighted running showed muscle- and stretch-shortening cycle phase-dependent neuromuscular adjustments that were repeatable across both runs. Importantly, hamstring (BF, biceps femoris; STSM, semitendinosus/semimembranosus) muscle activity increased during the braking (BF: +44 ± 18%, p &lt; 0.001) and push-off (BF: +49 ± 12% and STSM: +123 ± 14%, p &lt; 0.001 for both) phases, and even more so for ANX+ than for ANX−. During the braking phase, only ANX+ showed significant increases in BF (+41 ± 15%, p &lt; 0.001) and STSM (+53 ± 27%, p &lt; 0.001) activities. During the push-off phase, ANX+ showed a more than twofold increase in STSM activity compared to ANX− (+119 ± 10% vs. +48 ± 27, p &lt; 0.001 for both).Conclusion: The increase in hamstring activity during the braking and push-off phases may have accelerated the subsequent swing of the free-leg, likely counteracting the unweighting-induced slowing of stride frequency. This was even more pronounced in ANX+ than in ANX−, in an increased attempt not to deviate from their preferred running pattern. These results highlight the importance of individualizing LBPPT training and rehabilitation protocols, with particular attention to individuals with weak or injured hamstrings.
Optimizing drip fertigation at different periods to improve yield, volatile compounds and cup quality of Arabica coffee
Authors: Li Rongmei , Cheng Jinhuan , Liu Xiaogang , Wang Zhihui , Li Huiyong , Guo Jinjin , Wang Haidong , Cui Ningbo , Zhao Lu 
Published: June 2023

How to improve and regulate coffee bean yield and quality through split fertilization in the whole life cycle of coffee is still unclear and deserves further study. A field experiment of 5-year-old Arabica coffee trees was conducted for 2 consecutive years from 2020 to 2022. The fertilizer (750 kg ha-1 year-1, N-P2O5-K2O:20%-20%-20%) was split in three times at early flowering (FL), the berry expansion (BE), and the berry ripening (BR). Taking equal fertilization throughout the growth cycle (FL250BE250BR250) as the control check, variable fertilizations including FL150BE250BR350, FL150BE350BR250, FL250BE150BR350, FL250BE350BR150, FL350BE150BR250, and FL350BE250BR150. Leaf net photosynthetic rate (Anet), stomatal conductance (gs), transpiration rate (Tr), leaf water use efficiency (LWUE), carboxylation efficiency (CE), partial factor productivity of fertilizer (PFP), bean yield, crop water use efficiency (WUE), bean nutrients, volatile compounds and cup quality, and the correlation of nutrients with volatile compounds and cup quality was evaluated. FL350BE250BR150 had the maximum Anet and gs, followed by FL250BE350BR150. The highest dry bean yield and WUE were obtained from FL250BE350BR150, which increased by 8.86% and 8.47% compared with FL250BE250BR250 in two-year average. The ash, total sugar, fat, protein, caffeine and chlorogenic acid in FL250BE350BR150 were 6.47%, 9.48%, 3.60%, 14.02%, 4.85% and 15.42% higher than FL250BE250BR250. Cluster analysis indicated FL150BE350BR250, FL250BE350BR150, FL350BE150BR250 and FL350BE250BR150 under medium roasted degree increased pyrazines, esters, ketones and furans, FL150BE350BR250 and FL250BE350BR150 under dark roasted degree increased ketones and furans. The aroma, flavor, acidity and overall score of medium roasted coffee were higher than dark roasted coffee, while the body score of dark roasted coffee was higher than medium roasted coffee. The nutrient contents were correlated with the volatile compounds and cup quality. TOPSIS indicated that FL250BE350BR150 was the optimal fertilization mode in the xerothermic regions. The obtained optimum fertilization mode can provide a scientific basis for coffee fertilization optimization and management.
Ascorbate peroxidase plays an important role in photoacclimation in the extremophilic red alga Cyanidiococcus yangmingshanensis
Authors: Fu Han-Yi , Wang Ming-Wei 
Published: June 2023

IntroductionAcidothermophilic cyanidiophytes in natural habitats can survive under a wide variety of light regimes, and the exploration and elucidation of their long-term photoacclimation mechanisms promises great potential for further biotechnological applications. Ascorbic acid was previously identified as an important protectant against high light stress in Galdieria partita under mixotrophic conditions, yet whether ascorbic acid and its related enzymatic reactive oxygen species (ROS) scavenging system was crucial in photoacclimation for photoautotrophic cyanidiophytes was unclear.MethodsThe significance of ascorbic acid and related ROS scavenging and antioxidant regenerating enzymes in photoacclimation in the extremophilic red alga Cyanidiococcus yangmingshanensis was investigated by measuring the cellular content of ascorbic acid and the activities of ascorbate-related enzymes.Results and discussionAccumulation of ascorbic acid and activation of the ascorbate-related enzymatic ROS scavenging system characterized the photoacclimation response after cells were transferred from a low light condition at 20 μmol photons m–2 s–1 to various light conditions in the range from 0 to 1000 μmol photons m–2 s–1. The activity of ascorbate peroxidase (APX) was most remarkably enhanced with increasing light intensities and illumination periods among the enzymatic activities being measured. Light-dependent regulation of the APX activity was associated with transcriptional regulation of the chloroplast-targeted APX gene. The important role of the APX activity in photoacclimation was evidenced by the effect of the APX inhibitors on the photosystem II activity and the chlorophyll a content under the high light condition at 1000 μmol photons m–2 s–1. Our findings provide a mechanistic explanation for the acclimation of C. yangmingshanensis to a wide range of light regimes in natural habitats.
The effects of executive coaching on behaviors, attitudes, and personal characteristics: a meta-analysis of randomized control trial studies
Authors: Nicolau Andreea , Candel Octav Sorin , Constantin Ticu , Kleingeld Ad 
Published: June 2023

BackgroundA growing number of studies emphasize executive coaching as an effective developmental tool that managers can use to increase their performance in organizational settings. However, the coaching research suggests a large variety of processes and outcomes, lacking clarity on the primary psychological dimensions most impacted.MethodReviewing 20 studies with a rigorous methodological design that used control trials and pre-post tests, we evaluated and compared the relative effects of coaching on different types and sub-types of outcomes by means of a classification of coaching outcomes based on previously used taxonomies.ResultsThe results indicate that the impact of coaching on behavioral outcomes was higher compared to attitudes and person characteristics outcomes, suggesting that behavioral coaching outcomes, especially cognitive behavioral activities, are the most impacted by executive coaching. Moreover, we found significant positive effects for some specific outcomes, such as self-efficacy, psychological capital, and resilience, indicating that executive coaching is effective in producing change even on dimensions considered relatively stable over time. The results show no moderation effects of the number of sessions. The length of the coaching program was a significant moderator only for the attitudes outcomes.DiscussionThese findings provide evidence that executive coaching is a powerful instrument for organizations to support positive change and personal development.
The influence of leadership on employees' employability: a bibliometric analysis, systematic literature review, and research agenda
Authors: Hoedemakers Joost , Vanderstukken Arne , Stoffers Jol 
Published: June 2023

IntroductionPolicymakers, researchers, and practitioners have recently begun treating employability-an individual's ability to possess and continuously adjust and acquire up-to-date competencies, flexibility, adaptability, and openness to change-as crucial to enabling employees to respond to ubiquitous and rapid changes in organizations (e.g., changing tasks and work-related processes). Research into ways to enhance employability, particularly through supervisor leadership, which, for example, facilitates training and competence development, has thus grown in popularity. A review on leadership as an antecedent of employability is both evident and timely. This review thus addresses the question of whether a supervisor's leadership influences employees' employability, and in which contexts and through which mechanisms it does so.MethodsAs preliminary study we conducted a bibliometric analysis (which corroborated employability's recent rise in popularity) and as main study we conducted a systematic literature review. For this, the authors independently searched for articles, which met the inclusion criteria and subsequently were included for full text analysis. The authors also independently used the forward and backward snowballing technique for identifying additional articles which met the inclusion criteria and subsequently were included for full text analysis. The procedure resulted in 17 articles in total.ResultsMost of the articles identified positive relationships among several conceptualizations of supervisor leadership and employee employability, such as transformational leadership and leader-member exchange, and to a lesser extent, servant leadership and perceived supervisor support. This review suggests that such relationships occur across different work contexts, such as educational, SMEs, healthcare, and several other industries, and these contexts also vary geographically.DiscussionThe relationships among supervisor leadership and employee employability are largely explained using a social exchange perspective, which means that the positive influence of leadership on employability is itself influenced by a two-way social exchange relationship between supervisor and employees. The quality of the dyadic relationship between leader and followers thus determines the extent to which leaders offer valuable resources such as training and feedback, which subsequently enhances employees' employability. This review demonstrates that investing in supervisors' leadership is a valuable HRM strategy that fosters employability, and it identifies practical implications that inform policy and practice and sets an agenda for future employability research.
Shall we play together? Game-based learning for engagement and classroom climate in Spanish socially deprived communities
Authors: Rodríguez-Ferrer José M. , Manzano-León Ana , Fernández-Jiménez Carolina , Luque de la Rosa Antonio , Fernández-Campoy Juan M. , Aguilar-Parra José M. 
Published: June 2023

PurposeThe purpose of this study is to analyze the effects of a game-based learning (GBL) program on the classroom climate and engagement of high schools in socially deprived communities in Spain.MethodsThe study included 277 students from two secondary schools located in Southern Spain, situated in Zones in Need of Social Transformation. Sampling was non-probabilistic and accidental, based on the accessibility of the school and the willingness of the management and teaching staff to participate in the GBL program. The study employed a control group and two experimental groups (cooperative games group only and cooperative and competitive games group) to compare pre-test and post-test data in both groups. The Brief Class Climate Scale and Engagement Inventory, validated in academic literature, were used as assessment instruments.ResultsThe study used a series of ANOVA tests to compare the experimental groups with the control group. The results indicated statistically significant changes in all study variables. In all cases, the experimental groups demonstrated greater benefits than the control group.Discussion and conclusionThe study findings reveal that games can provide significant benefits to students, regardless of whether they are cooperative or competitive. The study provides evidence of the benefits of GBL in high schools located in socially deprived communities in Spain.
Psychological wellbeing in adult adoptees: current age and developmental tasks
Authors: Melero Sandra , Verdugo Laura , Sánchez-Sandoval Yolanda 
Published: June 2023

IntroductionStudies about adult adoptees are normally focused on the differences in adjustment difficulties between them and non-adoptees. However, there has been less research about adoptees' positive and developmental adjustment in adulthood. The aim of this study is to test a model of the mediating role of adoptees' achievement of adulthood tasks in the relationship between current age and psychological wellbeing.Materials and methodsThe sample consisted of 117 adults who were adopted as children by Spanish families. Their current mean age is 28.3 years. Participants underwent an interview and completed Ryff's Psychological WellBeing Scales.ResultsFindings show that current age is directly and negatively related to psychological wellbeing [c′ = −0.039, 95% CI (−0.078, −0.001)], and the relationship between these variables is mediated by adoptees' achievement of adulthood tasks [indirect effect = 0.035, 95% CI (.014, 0.059)].DiscussionThe findings support traditional theories about transitioning to adulthood, and adds relevant information about this transition in adoptees. Moreover, this work indicates a new way of assessing adoption success, based on long-term measures and normative variables. Services providers should account for the importance of supporting young people on their life transitions and promoting their wellbeing, especially among those who started from disadvantaged contexts.
Assessing hypertension and diabetes knowledge, attitudes and practices among residents in Akatsi South District, Ghana using the KAP questionnaire
Authors: Asante Dorothy O. , Dai Anran , Walker Anita N. , Zhou Zhou , Kpogo Senam A. , Lu Rongzhu , Huang Kaizong , Zou Jianjun 
Published: June 2023

ObjectiveLow awareness of hypertension and diabetes is a public health concern in Ghana. Assessing the general population’s behaviour via knowledge, attitude, and practice (KAP) will be invaluable in these diseases, where prevention and control need a lifelong commitment to a healthy lifestyle. Hence, our goal was to assess the behaviour of Akatsi South residents towards the diseases to assist health providers in implementing tailored intervention programs.MethodsThis was a population-based cross-sectional study with 150 adults (18–70 years) from November to December 2021. A semi-structured questionnaire with face-to-face interviews was used to obtain data. All variables in the model had descriptive statistics. The Chi-square (χ2) test was used to examine correlations between variables, and a value of p &lt; 0.05 was considered statistically significant. The factors associated with checking blood sugar levels and blood pressure were determined using binary logistic regression.ResultsThe respondents’ mean age and BMI were 32.40 years (± 12.07) and 24.98 kg/m2 (± 2.36), respectively. Only 46.67% of the respondents frequently monitor their blood pressure and 17.33% their blood glucose (at least once a year). Less than half of those surveyed had a good knowledge of hypertension (42.7%) and diabetes (32.0%), whereas nearly 3/4 had poor attitudes regarding both conditions. A binary logistic regression analysis revealed that having a good attitude toward hypertension (exp B = 2.479, p = 0.036) and diabetes (exp B = 4.547, p = 0.009) were the participants’ strongest predictor of blood pressure and sugar level checks. However, being overweight (exp B = 0.046, p = 0.002,) or obese (exp B = 0.144, p = 0.034) negatively influenced the frequency with which our respondents checked their blood glucose levels.ConclusionIn the study, we found that the population generally has poor knowledge, which affects their behaviour (attitudes and practices) towards the diseases. To enable healthcare practitioners to reduce disease-associated mortality and morbidity in the future, frequent public health education and promotion about the conditions is critical to closing the knowledge gap.
Topic evolution and sentiment comparison of user reviews on an online medical platform in response to COVID-19: taking review data of Haodf.com as an example
Authors: Li Chaoyang , Li Shengyu , Yang Jianfeng , Wang Jingmei , Lv Yiqing 
Published: June 2023

IntroductionThroughout the COVID-19 pandemic, many patients have sought medical advice on online medical platforms. Review data have become an essential reference point for supporting users in selecting doctors. As the research object, this study considered Haodf.com, a well-known e-consultation website in China.MethodsThis study examines the topics and sentimental change rules of user review texts from a temporal perspective. We also compared the topics and sentimental change characteristics of user review texts before and after the COVID-19 pandemic. First, 323,519 review data points about 2,122 doctors on Haodf.com were crawled using Python from 2017 to 2022. Subsequently, we employed the latent Dirichlet allocation method to cluster topics and the ROST content mining software to analyze user sentiments. Second, according to the results of the perplexity calculation, we divided text data into five topics: diagnosis and treatment attitude, medical skills and ethics, treatment effect, treatment scheme, and treatment process. Finally, we identified the most important topics and their trends over time.ResultsUsers primarily focused on diagnosis and treatment attitude, with medical skills and ethics being the second-most important topic among users. As time progressed, the attention paid by users to diagnosis and treatment attitude increased—especially during the COVID-19 outbreak in 2020, when attention to diagnosis and treatment attitude increased significantly. User attention to the topic of medical skills and ethics began to decline during the COVID-19 outbreak, while attention to treatment effect and scheme generally showed a downward trend from 2017 to 2022. User attention to the treatment process exhibited a declining tendency before the COVID-19 outbreak, but increased after. Regarding sentiment analysis, most users exhibited a high degree of satisfaction for online medical services. However, positive user sentiments showed a downward trend over time, especially after the COVID-19 outbreak.DiscussionThis study has reference value for assisting user choice regarding medical treatment, decision-making by doctors, and online medical platform design.