bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Utility of MRI in Evaluating Ruptures of the Patellar Tendon
Authors: Otlans Peters , Heimur Juliana , Sonnier John Hayden , Gibby Devyn , Freedman Kevin B. 
Published: January 2023

Background: Although the identification of patellar tendon rupture is a clinical diagnosis aided by standard radiography, magnetic resonance imaging (MRI) may aid in identifying the location of the rupture and concomitant pathology. Purpose: To evaluate the characteristics of patellar tendon tears needing surgical repair and to determine whether patient or injury factors were predictive of tear location. Study Design: Case series; Level of evidence, 4. Methods: Consecutive patients who underwent primary patellar tendon repair for rupture between May 15, 2017, and April 10, 2020, were reviewed retrospectively. Exclusion criteria included age <18 years, surgical treatment of multiligamentous knee injury, laceration injury, and knee arthroplasty. Radiographs, MRI scans, MRI reports, clinic notes, and operative notes were evaluated. Statistical analysis was performed to determine factors associated with tear location, complications, and reoperation. Results: In total, 147 patients and 156 tendon tears were included; 82.1% of the tears were patellar avulsions, 14.7% were midsubstance or complex tears, and 3.2% were tibial avulsions. Patient and injury characteristics (body mass index, race, medical comorbidities, presence of patellar tendinitis, mechanism of injury, Insall-Salvati ratio, and the presence of infrapatellar bone fragments) were not predictive of tear location ( P > .05). Patellar tendon ruptures were able to be clinically diagnosed correctly in >99% of cases. MRI was used to evaluate 77 (49.4%) knees. Patients who underwent MRI before surgery were more likely to have a history of preexisting tendinitis ( P = .015) and a lower preoperative Insall-Salvati ratio (1.68 vs 1.52; P = .017). Conclusion: Patient and injury factors were not predictive of tear location. The majority of patellar tendon tears were avulsion-type injuries from the inferior patella. MRI was not necessary to aid in the diagnosis of patellar tendon rupture, as 99.4% of tears were able to be diagnosed clinically without advanced imaging.
Scheimpflug imaging for evaluation of intraocular lens position in modified flanged scleral fixated intraocular lens
Authors: Oli Avadhesh , Yadav Anil , Babu J. Ganesh , Balakrishnan Divya 
Published: January 2023

Background: Scleral fixation of intraocular lens (IOLs) is the most preferred technique for the management of aphakia and the techniques have evolved over the years. These methods have their advantages and disadvantages, however, the major concern being the position of the intraocular lens, its stability and complications. The final IOL position is the major determinant of the final visual acuity, and various imaging modalities have been used to quantify the IOL tilt. Objectives: Use of Scheimpflug imaging to evaluate the IOL tilt in modified flanged scleral-fixated intraocular lens (MFSIOL). Design: Retrospective chart review of 41 consecutive patients who underwent MFIOL. Methods: We conducted a retrospective chart review of 41 consecutive patients who underwent MFIOL. The baseline and final best-corrected visual acuity (BCVA), refractive error, and clinical examination findings were recorded. The vertical and horizontal tilts of the IOLs were calculated using the Scheimpflug image. The IOL tilt (in degrees) in the vertical and horizontal axes was the primary outcome and the BCVA, residual refractive error, intraocular pressure, and surgical complications were secondary outcome measures. Results: The mean baseline BCVA was logMAR 0.49, which improved to logMAR 0.356 ( p < .005) after the surgery. The mean IOL tilt in the vertical axis was 3.40° (range of 0.0°–8.5°, interquartile range: 1.21–5.66) and in the horizontal axis was 1.35° (range of 0.60°–4.620°, interquartile range: 0.44–1.86), respectively. There was no correlation between angle of IOL tilt and UCVA ( r = 0.089, p = 0.580), BCVA ( r = 0.109, p = 0.498), final spherical error ( r = 0.081, p = 0.615), cylindrical error ( r = 0.207, p = 0.195), axial length ( r = 0.105, p = 0.514), and IOL power ( r = –0.139, p = 0.388) Conclusion: Modified flanged IOL (MFIOL) is an alternative technique for intrascleral fixation of IOL resulting in good lens stability. The IOL tilt achieved by this technique is minimal and did not influence the final visual outcome or spectacle correction. Scheimpflug imaging is simple and non-invasive method to measure the IOL tilt. Plain Language Summary: Scheimpflug imaging for modified flanged scleral fixated lens position This study on 41 eyes was aimed to analyze the lens tilt using Scheimpflug imaging in cases of modified flanged scleral fixation of intraocular lens (MFSFIOL), which is a novel technique to minimize the complications and simplify the procedure. The intraocular lens (IOL) remained stable with an acceptable range of vertical and horizontal tilt. There was no significant effect of IOL tilt on the final best-corrected visual acuity (BCVA) or spectacle correction. Scheimpflug imaging is an accurate and non-invasive technique for assessment of lens position in the patients with intrascleral fixation of IOL.
Synthesis of Fe-deficient eudialyte analogues: Relationships between the composition of the reaction system and crystal-chemical features of the products
Authors: Kovalskaya Tatiana N. , Ermolaeva Vera N. , Chukanov Nikita V. , Varlamov Dmitry A. , Kovalskiy Georgy A. , Zakharchenko Egor S. , Kalinin Georgy M. , Chaichuk Korney D. 
Published: January 2023

AbstractEudialyte-related compounds have been synthesised hydrothermally at T = 600°C and P = 2 kbar from a stoichiometric mixture of Na2CO3, CaO, Fe2O3, ZrOCl2 and SiO2 using the Na:Ca:Fe:Zr:Si ratios corresponding to the eudialyte end-member Na15Ca6Fe3Zr3Si(Si25O73)(OH)Cl2⋅H2O, in the presence of 1 M aqueous solutions of NaCl and NaF. The synthesis was carried out in platinum ampoules over 10 days. Natural raslakite (a Ca-deficient member of the eudialyte group) was used as a seed and added in amounts corresponding to 2 wt.% of the whole charge. The products were characterised by powder X-ray diffraction, IR and Raman spectroscopy, morphological features, and electron probe microanalyses. In experiments with NaCl, almost pure eudialyte-type compounds were obtained. Synthesis in the presence of a NaF solution resulted in the formation of a F-dominant eudialyte-type compound related to raslakite as the main product and aegirine, vlasovite and lalondeite as by-products. All synthesised eudialyte-type compounds are Zr-rich and Fe-deficient, similar to eudialyte-group minerals from hyperagpaitic rocks related to foyaites. The increased NaCl contents in the reaction system results in increased Ca content in the synthesised eudialyte-related compounds. The crystal-chemical formulae of the synthesised eudialyte-type compounds are derived based on general regularities established earlier for eudialyte-group minerals.
A hybrid machine learning framework to improve prediction of all-cause rehospitalization among elderly patients in Hong Kong
Authors: Guan Jingjing , Leung Eman , Kwok Kin-on , Chen Frank Youhua 
Published: January 2023

Abstract
Background
Accurately estimating elderly patients’ rehospitalisation risk benefits clinical decisions and service planning. However, research in rehospitalisation and repeated hospitalisation yielded only models with modest performance, and the model performance deteriorates rapidly as the prediction timeframe expands beyond 28 days and for older participants.

Methods
A temporal zero-inflated Poisson (tZIP) regression model was developed and validated retrospectively and prospectively. The data of the electronic health records (EHRs) contain cohorts (aged 60+) in a major public hospital in Hong Kong. Two temporal offset functions accounted for the associations between exposure time and parameters corresponding to the zero-inflated logistic component and the Poisson distribution’s expected count. tZIP was externally validated with a retrospective cohort’s rehospitalisation events up to 12 months after the discharge date. Subsequently, tZIP was validated prospectively after piloting its implementation at the study hospital. Patients discharged within the pilot period were tagged, and the proposed model’s prediction of their rehospitalisation was verified monthly. Using a hybrid machine learning (ML) approach, the tZIP-based risk estimator’s marginal effect on 28-day rehospitalisation was further validated, competing with other factors representing different post-acute and clinical statuses.

Results
The tZIP prediction of rehospitalisation from 28 days to 365 days was achieved at above 80% discrimination accuracy retrospectively and prospectively in two out-of-sample cohorts. With a large margin, it outperformed the Cox proportional and linear models built with the same predictors. The hybrid ML revealed that the risk estimator’s contribution to 28-day rehospitalisation outweighed other features relevant to service utilisation and clinical status.

Conclusions
A novel rehospitalisation risk model was introduced, and its risk estimators, whose importance outweighed all other factors of diverse post-acute care and clinical conditions, were derived. The proposed approach relies on four easily accessible variables easily extracted from EHR. Thus, clinicians could visualise patients’ rehospitalisation risk from 28 days to 365 days after discharge and screen high-risk older patients for follow-up care at the proper time.
Predictors of incident reversible and potentially reversible cognitive frailty among Taiwanese older adults
Authors: Hwang Hei-Fen , Suprawesta Lalu , Chen Sy-Jou , Yu Wen-Yu , Lin Mau-Roung 
Published: January 2023

Abstract
Background
Few studies emphasize on predictors of incident cognitive frailty (CF) and examine relationships between various gait characteristics and CF. Therefore, we conducted a 2-year prospective study to investigate potential predictors, including gait characteristics, of incident reversible CF (RCF) and potentially RCF (PRCF) among Taiwanese older adults.

Methods
Eligible participants were individuals aged ≥ 65 years, who could ambulate independently, and did not have RCF/PRCF at the baseline. The baseline assessment collected information on physical frailty and cognitive measures, in addition to sociodemographic and lifestyle characteristics, preexisting comorbidities and medications, gait characteristics, Tinetti’s balance, balance confidence as assessed by Activities-specific Balance Confidence (ABC) scale, and the depressive status as assessed by the Geriatric Depression Scale. The Mini-Mental State Examination (MMSE), Mattis Dementia Rating Scale, and Digit Symbol Substitution Test were used to evaluate cognitive functions. Incident RCF and PRCF were ascertained at a 2-year follow-up assessment.

Results
Results of the multinomial logistic regression analysis showed that incident RCF was significantly associated with older age (odds ratio [OR] = 1.05) and lower ABC scores (OR = 0.97). Furthermore, incident PRCF was significantly associated with older age (OR = 1.07), lower ABC scores (OR = 0.96), the presence of depression (OR = 3.61), lower MMSE scores (OR = 0.83), slower gait velocity (OR = 0.97), and greater double-support time variability (OR = 1.09).

Conclusions
Incident RCF was independently associated with older age and lower balance confidence while incident PRCF independently associated with older age, reduced global cognition, the presence of depression, slower gait velocity, and greater double-support time variability. Balance confidence was the only modifiable factor associated with both incident RCF and PRCF.
A case of novel, rapidly-growing Mycolicibacter kumamotonensis infection in a patient with severe pulmonary disease treated in New York City
Authors: Weidmann Maxwell D. , Wu Yuexiu , Wu Fann , Hapani Dhrupa D. , Green Daniel A. , Aaron Justin G. , Berry Gregory J. 
Published: January 2023

Abstract
Introduction
Mycolicibacter kumamotonensis is a slowly growing, non-chromogenic non-tuberculous mycobacteria (NTM) that was initially distinguished from the M. terrae complex in 2006. Since then it has been rarely reported as the cause of pulmonary and soft-tissue infections in both immunocompromised and immunocompetent patients.

Case presentation
We present a case of severe pulmonary disease due to Mycolicibacter kumamotonensis in a 57-year-old male who was immunocompetent at time of diagnosis, with a history of interstitial lung disease and a prior diagnosis of tuberculosis (TB). After initial treatment for TB in 2017, his condition stabilized until a recurrence in September 2021, leading to an evaluation for lung transplant in the setting of pulmonary fibrosis and emphysema which led to the identification of Mycolicibacter kumamotonensis. A lung transplant was completed, and the patient was successfully treated with a combination of Ethambutol, Azithromycin, and Rifabutin.

Conclusions
This represents the first case reported of M. kumamotonensis in a patient undergoing lung transplant, and the first case with rapid culture growth during identification of the organism (4 days). This report highlights the need for consideration of M. kumamotonensis as a pathogen in humans, with the potential for rapid growth in liquid media, and the importance of early identification to inform empiric therapy.
Ultrasound measurement of optic nerve sheath diameter in a healthy adult Colombian population
Authors: Trocha Guillermo , Bonilla Andrés , Romero Camilo , Palacios Jonathan , Molano-Gonzalez Nicolas 
Published: January 2023

Abstract
Background
Measurement of the optic nerve sheath diameter (ONSD) provides a rapid, safe, and easy method for detecting increased intracranial pressure (ICP). However, the normal mean and upper limit values may vary according to sex, age, ethnicity, and ultrasound technique.

Aim
We aimed to obtain the mean ONSD in a healthy Colombian adult population and to correlate it with demographic and anthropometric measures.

Methods
In a prospective study using a 10–13 MHz linear ultrasound probe, eye transverse diameter (ETD) and ONSD in the transverse (ONSD-TP) and sagittal planes (ONSD-SP) were measured in healthy adult volunteers in Bogota, Colombia.

Results
A total of 100 healthy subjects were included, with a mean age of 26,7 ± 8,3 years and 62 women. The mean ETD, ONSD-TP and ONSD-SP was 23.11 mm (95% confidence interval (CI): 22.90 mm-23.32 mm), 3.96 mm (95% CI: 3.85 mm-4.07 mm) and 4.0 mm (95% CI: 3.90 mm-4.11 mm), respectively. The ONSD in both planes ranged from 2.35 mm to 5.20 mm. There was a significant correlation between ONSD-SP and ONSD-TP (p < 0.0001) but no correlation between the ocular measures and demographic or anthropometric variables (p > 0.05). The intraclass correlation between the eyes was statistically significant.

Conclusion
Our study shows that ultrasound-measured ONSD in healthy adults in Colombia is similar to that found worldwide. An ONSD of 5.5 mm may be considered the upper limit for healthy adults in Colombia. ONSD can be measured in either plane; there is a good correlation between the two eyes; and ONSD is not modified by demographic or anthropometric characteristics.
Fetal pharyngeal glial heterotopia manifested as polyhydramnios: a rare case with difficult prenatal diagnosis
Authors: Ke Xiaoting , Cai Huaijie , Wang Wei , Lai Qingquan 
Published: January 2023

Abstract
Background
Glial heterotopia is a rare congenital developmental malformation that presents as tumor-like lesions of the nerve tissue that grow outside the nervous system, but are not true tumors. At present, most cases are reported in neonates and children and are very rarely found in fetuses. The present report describes a case of fetal pharyngeal glial heterotopia and associated imaging findings to better understand the disease in the future.

Case presentation
A 32-year-old pregnant woman was admitted to the hospital with polyhydramnios. An ultrasound examination revealed a hypoechoic mass in the neck of the fetus. Magnetic resonance imaging showed a well-defined mass with significant compression of the esophagus and airway. The amniotic fluid index was approximately 40 cm. Considering that difficulty swallowing and breathing may occur due to compression by the mass after birth, tracheotomy and mass resection should be performed immediately. The difficulty of the tumor resection procedure and the nature of the tumor are both factors affecting the prognosis of the fetus. The pregnant woman eventually chose to induce labor. The fetal pharyngeal mass was then resected and its pathological examination indicated pharyngeal glial heterotopia.

Conclusions
Polyhydramnios due to pharyngeal glial heterotopia is extremely rare and accurate prenatal diagnosis is challenging. Clinical diagnosis of glial heterotopia in preterm fetuses is difficult. Therefore, understanding glial heterotopia is helpful to improve clinical treatment options.
Porphyromonas gingivalis predicts local recurrence after endoscopic submucosal dissection of early esophageal squamous cell carcinoma or precancerous lesion
Authors: Gao She-Gan , Qi Zhi-Peng , Qi Yi-Jun , Hou Ying-Yong , Liu Yi-Wen , Li Meng-Xiang , Li Bing , Sun Di , Shi Qiang , Cai Shi-Lun , Zhou Ping-Hong , Zhong Yun-Shi 
Published: January 2023

Abstract
Background
Porphyromonas gingivalis plays an oncogenic role in development and progression of esophageal squamous cell carcinoma (ESCC). However, the impact of P. gingivalis on local recurrence of early ESCC or precancerous lesion after ESD treatment remains unknown. The present study aimed to evaluate the impact of P. gingivalis on local recurrence after ESD treatment of early ESCC or high-grade dysplasia (HGD).

Methods
The amount of P. gingivalis was assessed by immunohistochemistry in 205 patients with early ESCC or HGD. Univariate and multivariate Cox regression analyses were performed to determine the effect of P. gingivalis on local recurrence. Propensity score matching analysis was performed to reduce the imbalance of baseline characteristics. A nomogram integrating significant prognostic factors was built for local recurrence prediction.

Results
The amount of P. gingivalis increased significantly in neoplasms that invaded up to muscularis mucosa and submucosa compared with lesions confined to epithelium or lamina propria. Overabundance of P. gingivalis was positively associated with invasion depth, post-ESD stricture and local recurrence. Univariate and multivariate Cox regression analyses revealed that P. gingivalis, longitudinal length of lesion and lymphovascular invasion were independent predictors for post-ESD recurrence. A nomogram comprising P. gingivalis, lymphovascular involvement, and lesion length performed well for prediction of post-ESD local recurrence with the concordance indices of 0.72 (95%CI, 0.62 to 0.80), 0.72 (95%CI, 0.63 to 0.80), and 0.74 (95%CI, 0.65 to 0.83) in the validation cohort, the entire cohort, and the subcohort after PSM, respectively.

Conclusion
P. gingivalis overabundance is a risk factor and a potential predictor for local recurrence of early ESCC or HGD after ESD treatment. Thus, clearance of P. gingivalis represents an attractive strategy for prognosis improvement and for prevention of ESCC.
Resilience and problematic smartphone use: a moderated mediation model
Authors: Hao Zejun , Jin Liangyi , Huang Jinzi , Akram Hafiza Rabia , Cui Qian 
Published: January 2023

Abstract
Background
Problematic smartphone use (PSU) is adversely correlated with resilience. To completely comprehend the mechanism underlying this relationship, however, more investigation is required.

Methods
For this cross-sectional study, the method of stratified random cluster sampling was applied. 834 Chinese undergraduate students (aged 17 to 24) were recruited, and self-reported questionnaires were administered to measure their levels of resilience, perceived social support, the sense of school belonging, and habitual and problematic smartphone use.

Results
The findings showed that resilience both directly and indirectly predicted PSU through perceived social support and the sense of school belonging. Additionally, there were significant moderating effects of habitual smartphone use between resilience and perceived social support, the sense of school belonging, and PSU.

Conclusions
Our research identified the negative influence of resilience on PSU, and specifically, highlighted the mediation effects of perceived social support and the sense of school belonging. Of significance, we also found the moderation effect of habitual smartphone use in the development of PSU.
Behavioural Change Techniques in Health Coaching-Based Interventions for Type 2 Diabetes: A Systematic Review and Meta-Analysis
Authors: Almulhim Abdullah N. , Hartley Hannah , Norman Paul , Caton Samantha J. , Doğru Onur Cem , Goyder Elizabeth 
Published: January 2023

Abstract
Background
Given the high rates globally of Type 2 Diabetes Mellitus (T2DM), there is a clear need to target health behaviours through person-centred interventions. Health coaching is one strategy that has been widely recognised as a tool to foster positive behaviour change. However, it has been used inconsistently and has produced mixed results. This systematic review sought to explore the use of behaviour change techniques (BCTs) in health coaching interventions and identify which BCTs are linked with increased effectiveness in relation to HbA1C reductions.

Methods
In line with the PICO framework, the review focused on people with T2DM, who received health coaching and were compared with a usual care or active control group on HbA1c levels. Studies were systematically identified through different databases including Medline, Web of science, and PsycINFO searches for relevant randomised controlled trials (RCTs) in papers published between January 1950 and April 2022. The Cochrane collaboration tool was used to evaluate the quality of the studies. Included papers were screened on the reported use of BCTs based on the BCT taxonomy. The effect sizes obtained in included interventions were assessed by using Cohen’s d and meta-analysis was used to estimate sample-weighted average effect sizes (Hedges’ g).

Results
Twenty RCTs with a total sample size of 3222 were identified. Random effects meta-analysis estimated a small-sized statistically significant effect of health coaching interventions on HbA1c reduction (g+ = 0.29, 95% CI: 0.18 to 0.40). A clinically significant HbA1c decrease of ≥5 mmol/mol was seen in eight studies. Twenty-three unique BCTs were identified in the reported interventions, with a mean of 4.5 (SD = 2.4) BCTs used in each study. Of these, Goal setting (behaviour) and Problem solving were the most frequently identified BCTs. The number of BCTs used was not related to intervention effectiveness. In addition, there was little evidence to link the use of specific BCTs to larger reductions in HbA1c across the studies included in the review; instead, the use of Credible source and Social reward in interventions were associated with smaller reductions in HbA1c.

Conclusion
A relatively small number of BCTs have been used in RCTs of health coaching interventions for T2DM. Inadequate, imprecise descriptions of interventions and the lack of theory were the main limitations of the studies included in this review. Moreover, other possible BCTs directly related to the theoretical underpinnings of health coaching were absent. It is recommended that key BCTs are identified at an early stage of intervention development, although further research is needed to examine the most effective BCTs to use in health coaching interventions.

Trial registration
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021228567.