bluuebunny/crossref_metadata_2025_split huggingface dataset:
The taxonomic status of Hymenodora (Crustacea: Oplophoroidea): morphological and molecular analyses suggest a new family and an undescribed diversity deep in the sea
Authors: Lunina Anastasiia , Kulagin Dmitry , Vereshchaka Alexander 
Published: August 2023

Abstract
Hymenodora represents the most scantily studied branch of the pelagic shrimp belonging to the superfamily Oplophoroidea. We present a phylogenetic revision based on 80 morphological characters and six genes. Molecular and morphological phylogenetic analyses, along with molecular distances calculated with the use of six genes, suggest a family-level status of the clade Hymenodoridae including Hymenodora and Sclerodora, which is also supported by morphological characters linked to the mouthparts. We erect and diagnose a new family and provide a key to families of Oplophoroidea. We tested seven morphological characters, found that only one of them provides a confident identification of Hymenodora gracilis and Hymenodora glacialis complexes. We provide an amended key to species of Hymenodoridae. Molecular trees, along with genetic distances based on COI and 16S genetic markers, showed that H. gracilis and H. glacialis represent complexes of cryptic lineages that cannot be identified on the basis of solitary morphological characters; however, when we included seven morphological characters and ran principal component analysis and generalized linear mixed models, we could distinguish all cryptic lineages confidently. Evolutionary traits of Hymenodoridae are linked to adaptations to feeding in the deep sea (mouthparts), strengthening the membranous carapace (carinae, sulci) and passive defence (shape and proportions of the rostrum and carapace).
Streptomyces cocklensis DSM 42063 and Actinacidiphila bryophytorum DSM 42138 Colonize Arabidopsis thaliana and Modulate Its Proteome
Authors: Arsène-Ploetze Florence , Rompais Magali , Alioua Abdelmalek , Cognat Valérie , Erhardt Mathieu , Graindorge Stefanie , Koechler Sandrine , Mutterer Jérôme , Carapito Christine , Schaller Hubert 
Published: August 2023

Streptomycetaceae are found ubiquitously within plant microbiota. Several species belonging to this family are plant growth-promoting bacteria or may inhibit phytopathogens. Such bacteria therefore exert crucial functions in host development and resistance to stresses. Recent studies have shown that plants select beneficial bacteria into their microbiota. However, the selection process and the molecular mechanisms by which selected bacteria modulate the physiology of their host are not yet fully understood. Previous work revealed that the metabolic status of Arabidopsis thaliana was crucial for the selection of Streptomycetaceae into the microbiota, in particular bacteria phylogenetically related to Streptomyces cocklensis or Actinacidiphila bryophytorum (previously named Streptomyces bryophytorum). Here, the Arabidopsis-Streptomycetaceae interaction was further depicted by inoculating axenic A. thaliana with S. cocklensis DSM 42063 or A. bryophytorum DSM 42138. We showed that these two bacteria colonize A. thaliana ecotype Columbia-0 plants, but the colonization efficiency is reduced in a chs5 mutant of the same ecotype, being altered in isoprenoid, phenylpropanoid, and lipid profiles. We observed that A. bryophytorum inhibits growth of the chs5 mutant but not of the wild type, suggesting that the Arabidopsis-Actinacidiphila interaction depends on the metabolic status of the host. Using a mass spectrometry-based proteomic approach, we showed that S. cocklensis and A. bryophytorum modulate the A. thaliana proteome, in particular components involved in photosynthesis or phytohormone homeostasis. This study unveils specific aspects of the Arabidopsis-Streptomycetaceae interaction and highlights its complexity and diversity. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
The Predictive Potential of Nutritional and Metabolic Burden
Authors: Tretiakov Peter S. , Thomas Zach , Krol Oscar , Joujon-Roche Rachel , Williamson Tyler , Imbo Bailey , Dave Pooja , McFarland Kimberly , Mir Jamshaid , Vira Shaleen , Diebo Bassel , Schoenfeld Andrew J. , Passias Peter G. 
Published: August 2023

Study Design:
A retrospective cohort review.

Objective:
To develop a scoring system for predicting increased risk of postoperative complications in adult spinal deformity (ASD) surgery based on baseline nutritional and metabolic factors.

Background:
Endocrine and metabolic conditions have been shown to adversely influence patient outcomes and may increase the likelihood of postoperative complications. The impact of these conditions has not been effectively evaluated in patients undergoing ASD surgery.

Materials and Methods:
ASD patients 18 years or above with baseline and two-year data were included. An internally cross-validated weighted equation using preoperative laboratory and comorbidity data correlating to increased perioperative complications was developed via Poisson regression. Body mass index (BMI) categorization (normal, over/underweight, and obese) and diabetes classification (normal, prediabetic, and diabetic) were used per the Centers for Disease Control and Prevention and the American Diabetes Associates parameters. A novel ASD-specific nutritional and metabolic burden score (ASD-NMBS) was calculated via Beta-Sullivan adjustment, and Conditional Inference Tree determined the score threshold for experiencing ≥1 complication. Cohorts were stratified into low-risk and high-risk groups for comparison. Logistic regression assessed correlations between increasing burden score and complications.

Results:
Two hundred one ASD patients were included (mean age: 58.60±15.4, sex: 48% female, BMI: 29.95±14.31, Charlson Comorbidity Index: 3.75±2.40). Significant factors were determined to be age (+1/yr), hypertension (+18), peripheral vascular disease (+37), smoking status (+21), anemia (+1), VitD hydroxyl (+1/ng/mL), BMI (+13/cat), and diabetes (+4/cat) (model: P<0.001, area under the curve: 92.9%). Conditional Inference Tree determined scores above 175 correlated with ≥1 post-op complication (P<0.001). Furthermore, HIGH patients reported higher rates of postoperative cardiac complications (P=0.045) and were more likely to require reoperation (P=0.024) compared with low patients.

Conclusions:
The development of a validated novel nutritional and metabolic burden score (ASD-NMBS) demonstrated that patients with higher scores are at greater risk of increased postoperative complications and course. As such, surgeons should consider the reduction of nutritional and metabolic burden preoperatively to enhance outcomes and reduce complications in ASD patients.
An Analysis of Community-Level Socioeconomic Status Effects on Pricing Transparency and Variability of Hand Surgery Procedures
Authors: Rhee Ben S. , Tanzer Joshua R. , Charvis Jodi S. , Kalliainen Loree K. 
Published: August 2023

Background:
The hospital price transparency final rule requires hospitals to publish pricing information about provided items and services by means of 2 methods: (1) a comprehensive machine-readable file and (2) a display tool of selected shoppable services. Using machine-readable files on hospital websites, the authors examined trends in pricing transparency and variation in association with community-level socioeconomic factors for 3 common hand surgery procedures among Association of American Medical Colleges–affiliated hospitals.

Methods:
Available discount cash prices and payer-specific negotiated prices for CPT codes 64721, 26615, and 25111 were recorded. Multivariate analysis was used to stratify hospitals into 2 groups based on their area’s median household income, percentage uninsured, and geographic practice cost index practice expense scores. Generalized linear mixed effects modeling was used to evaluate price variability against community-level financial characteristics of the patient population.

Results:
Of hospitals that met selection criteria, a majority did not display discount cash prices and payer-specific negotiated prices for the 3 procedures. Hospitals in lower-income areas and areas with a higher percentage of the uninsured tended to charge a higher average payer-specific negotiated price for CPT code 25111. They also tended to have greater variation in payer-specific negotiated prices than hospitals found in higher-income and lower-percentage-uninsured areas.

Conclusions:
This study demonstrates that considerable pricing variation and incomplete transparency exists for CPT codes 64721, 26615, and 25111 among Association of American Medical Colleges–affiliated hospitals. Patients in lower-income and higher-percentage-uninsured areas are more exposed to a higher variability and average of negotiated prices than those in higher-income areas, which may translate to higher out-of-pocket costs for those with higher coinsurance and less socioeconomic prowess.
Morphologic Severity and Age at Surgery Are Associated with School-Age Neurocognitive Outcomes in Metopic Craniosynostosis
Authors: Long Aaron S. , Hauc Sacha C. , Almeida Mariana N. , Alper David P. , Beiriger Justin , Rivera Jean Carlo , Goldstein Jesse , Mayes Linda , Persing John A. , Alperovich Michael 
Published: August 2023

Background:
Radiographic severity of metopic synostosis has been suggested as a predictor of long-term neurocognitive outcomes, and artificial intelligence (AI) has recently been used to quantify severity. Age at surgery is predictive of long-term neurocognition in sagittal synostosis but has not been adequately explored in metopic synostosis.

Methods:
Children ages 6 to 18 years with corrected metopic synostosis underwent testing of intelligence quotient, academic achievement, and visuomotor integration (VMI). Various manual measurements and AI-derived severity scores were determined. Scans were categorized as moderate or severe for head-to-head comparisons and multivariable linear regressions were used to assess the relationship of age at surgery and severity with neurocognitive outcomes.

Results:
A total of 41 patients with average age at testing of 10.8 ± 3.4 years were included. A total of 18 patients were in the severe group and 23 patients were in the moderate group, with average ages at surgery of 6.6 ± 2.7 and 10.6 ± 8.4 months, respectively (P = 0.062). Greater AI-derived severity was significantly associated with lower reading comprehension (P = 0.040 and 0.018) and reading composite scores (P = 0.024 and P = 0.008). Older age at surgery was significantly associated with lower VMI scores (P values ranging from 0.017 to 0.045) and reading composite scores (P = 0.047 and 0.019).

Conclusions:
This study suggests an association between greater AI-derived radiographic severity and lower reading ability in corrected metopic synostosis. Older age at surgery was independently associated with lower reading ability and VMI. Surgical correction may mitigate neurodevelopmental differences based on severity that have been observed preoperatively.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Risk, II.
Stochastic thermodynamics: dissipativity, accumulativity, energy storage and entropy production
Authors: Lanchares Manuel , Haddad Wassim M. 
Published: August 2023

In this paper, we develop an energy-based dynamical system model driven by a Markov input process to present a unified framework for stochastic thermodynamics predicated on a stochastic dynamical systems formalism. Specifically, using a stochastic dissipativity, losslessness and accumulativity theory, we develop a nonlinear stochastic port-Hamiltonian system model characterized by energy conservation and entropy non-conservation laws that are consistent with statistical thermodynamic principles. In particular, we show that the difference between the average stored system energy and the average supplied system energy for our stochastic thermodynamic model is a martingale with respect to the system filtration, whereas the difference between average system entropy production and the average system entropy consumption is a submartingale with respect to the system filtration.
This article is part of the theme issue ‘Thermodynamics 2.0: Bridging the natural and social sciences (Part 2)’.
Maximum power in evolution, ecology and economics
Authors: Hall Charles A. S. , McWhirter Timothy 
Published: August 2023

Ludwig Boltzmann suggested that natural selection was fundamentally a struggle among organisms for available energy. Alfred Lotka argued that organisms that capture and use more energy than their competition will have a selective advantage in the evolutionary process, i.e. the Darwinian notion of evolution was based on a fundamental, generalized energy principle. He extended this general principle from the energetics of a single organism or species to the energetics of entire energy pathways through ecosystems. Howard Odum and Richard Pinkerton, building on Lotka, extended this concept to ‘The maximum power principle’ and applied it to many biological and physical systems including human economies. We examine this history and how these ideas relate to concepts from other disciplines including philosophy. But there has been considerable confusion in understanding and applying these concepts which we attempt to resolve while providing various examples from routine life and discussing some unresolved issues.
This article is part of the theme issue ‘Thermodynamics 2.0: Bridging the natural and social sciences (Part 2)’.
‘The agency of observation not to be neglected’: complementarity, causality and the arrow of events in quantum and quantum-like theories
Authors: Plotnitsky Arkady 
Published: August 2023

The argument of this article is grounded in the irreducible interference of observational instruments in our interactions with nature in quantum physics and, thus, in the constitution of quantum phenomena versus classical physics, where this interference can, in principle, be disregarded. The irreducible character of this interference was seen by N. Bohr as the principal distinction between classical and quantum physics and grounded his interpretation of quantum phenomena and quantum theory. Bohr saw complementarity as a generalization of the classical ideal of causality, which defined classical physics and relativity. While intimated by Bohr, the relationships among observational technology, complementarity, causality and the arrow of events (a new concept that replaces the arrow of time commonly used in this context) were not addressed by him either. The article introduces another new concept, that of quantum causality, as a form of probabilistic causality. The argument of the article is based on a particular interpretation of quantum phenomena and quantum theory, defined by the concept of ‘reality without realism (RWR)’. This interpretation follows Bohr's interpretation but contains certain additional features, in particular the Dirac postulate. The article also considers quantum-like (Q-L) theories (based in the mathematics of QM) from the perspective it develops.
This article is part of the theme issue ‘Thermodynamics 2.0: Bridging the natural and social sciences (Part 2)’.
Phase transitions, KMS condition and decision making: an introductory model
Authors: Bagarello Fabio 
Published: August 2023

We consider a simple model of interacting agents asked to choose between ‘yes’ and ‘no’ to some given question. The agents are described in terms of spin variables, and they interact according to a mean field Heisenberg model. We discuss under which conditions the agents can come out with a common choice. This is made using, in a social context, the notion of KMS states and phase transitions.This article is part of the theme issue ‘Thermodynamics 2.0: Bridging the natural and social sciences (Part 2)’.
The effects of the modern evolutionary synthesis on the new organizational paradigm
Authors: Sunar Lütfi , Geçimli Gözde 
Published: August 2023

This paper discusses the connection between natural and social sciences through how the modern evolutionary synthesis approach, which emerged in biology, influenced social organizations. First, the paper examines the relationship of neo-evolutionism with organizational theories. Then the interaction between natural and social sciences is explained in the study. Afterwards, the relationship between neo-evolutionism and organization theory is handled around the discussions in this field. It has been emphasized that the flow of knowledge between sociology and biology is much more organic and mutual than expected. In other words, this study aims to draw attention to the methodological continuity of the interaction between evolution and organization theory from the very beginning to the present. In line with this purpose, the relationship between the transformation of the theory of evolution and the transformation of classical organizational theories is examined. In this study, it is claimed that the source of the paradigmatic interaction of neo-evolutionism and organization theories is the analogical relationship that began to be established between biology and sociology in the nineteenth century and that this relationship has turned into a much more organic structure than a mechanical and technical analogy in the historical process.
This article is part of the theme issue ‘Thermodynamics 2.0: Bridging the natural and social sciences (Part 2)’.
Long-term risk of repeat hospital admission involving self-harm by Aboriginal and non-Aboriginal people: A retrospective cohort study
Authors: Leckning Bernard , Borschmann Rohan , Hirvonen Tanja , Silburn Sven R. , Guthridge Steven , Robinson Gary W. 
Published: August 2023

AbstractBackgroundIdentify risk factors for repeat hospitalisation involving self-harm by Aboriginal and non-Aboriginal people in the Northern Territory (NT), Australia.MethodsA retrospective cohort study of hospitalisations involving suicidal ideation and/or self-harm between 1 July 2001 and 31 December 2013 followed up to 31 December 2018. Survival analyses identified demographic and clinical characteristics associated with repeat hospitalisation involving self-harm.ResultsThe risk of repeat hospitalisation involving self-harm was higher (HR 1.39; 95% CI: 1.22-1.59) amongst Aboriginal (n=2,304) than non-Aboriginal people (n=2,087). Compared to suicidal ideation only, a higher risk of repetition was observed for any self-harm method (aHR: 1.71; 95% CI: 1.37-2.12) amongst Aboriginal people and self-poisoning only (aHR: 1.45; 95% CI: 1.13-1.85) amongst non-Aboriginal people. Previous substance misuse was associated with a higher risk of repeat hospitalisation involving self-harm for Aboriginal (aHR: 1.7; 95% CI: 1.38-2.1) and non-Aboriginal (aHR: 1.6; 95% CI: 1.14-2.25) people. For non-Aboriginal people, several mental health diagnoses were associated with higher risks of repetition.LimitationsThe use of routinely collected administrative data limits analysis to only coded diagnoses and does not represent the full burden of self-harm and suicidal ideation in hospitals.ConclusionThe similarities and differences in long-term risk of repeat hospitalisation involving self-harm between Aboriginal and non-Aboriginal people pose distinct challenges for clinical management and prevention. The results emphasise the importance of comprehensive psychosocial assessment to properly understand the interplay of individual and contextual influences and highlights the need to better understand the availability and effectiveness of culturally tailored clinical interventions and community-based solutions.
Investigating the Neural Correlates of Processing Basic Emotions: A Functional Near-Infrared Spectroscopy (fNIRS) Study
Authors: Yükselen Gülnaz , Öztürk Ozan Cem , Canlı Gümüş Deniz , Erdoğan Sinem Burcu 
Published: August 2023

ABSTRACTEmotion regulation, a fundamental aspect of human functioning, involves the ability to monitor, evaluate, and modify emotional responses. Understanding the neural mechanisms underlying emotion regulation holds significant implications across various disciplines, including psychology, neuroscience, and clinical psychiatry. This study aims to explore the neural correlates of emotion regulation using functional near-infrared spectroscopy (fNIRS) with a specific focus on the prefrontal cortex (PFC). fNIRS, a non-invasive and portable brain imaging technology, offers an excellent opportunity to investigate real-life emotion processing with high temporal resolution. Twenty participants underwent an experimental protocol where they viewed emotional pictures from the International Affective Picture System (IAPS) database, varying in valence (positive and negative) and arousal (high and low). fNIRS data were collected during the picture presentation, and the hemodynamic responses in the PFC were analyzed. The findings demonstrated distinct spatiotemporal patterns of activation associated with different emotional states. Positive valence stimuli elicited higher hemodynamic activation in bilateral dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC) regions when compared to negative valence stimuli. On the other hand, negative valence stimuli induced higher activation in the medial prefrontal cortex (mPFC) when compared to positive valence stimuli. Moreover, high arousal positive valence stimuli evoked higher activation in the left DLPFC region when compared to high arousal negative valence stimuli. These results shed light on the differential neural processing of positive and negative emotions within the PFC, supporting the notion of lateralized emotional processing. The study validates the feasibility of fNIRS for objectively capturing emotion-related neural activity, providing valuable insights for future applications in emotion recognition and affective brain-computer interfaces (BCIs). Understanding the neural basis of emotion regulation has significant implications for designing targeted interventions for individuals experiencing emotion dysregulation disorders. Additionally, the integration of fNIRS technology into affective BCIs may offer new possibilities for real-time emotion detection and communication in populations with communication challenges.
Implementation and testing of a biohybrid transition microelectrode array for neural recording and modulation
Authors: Ahmed Benozir , Binder Simon , Boroomand Saeed , Strathman Hunter J. , Hantak Michael , Shepherd Tate , Ehrenhofer Adrian , Zhang Huannan , Shepherd Jason , Solzbacher Florian , Tresco Patrick A. , Blair Steve , Reiche Christopher F. , Fan Yantao 
Published: August 2023

AbstractRecent advances in microtissue engineered neural networks have opened avenues for the fabrication of biohybrid intracortical brain implants. To date, however, the experimental validation of these biohybrid implants has been restricted to singularly positioned electrodes, with the functionality confined to optical neuromodulation and neural recording. We present for the first time a biohybrid transition microelectrode array (TMEA) comprising a 4×4 matrix of biohybrid electrodes. These electrodes are expected to project axons into the brain, thereby establishing synaptic connections for electrical readout and excitation. Our device thus offers a promising pathway to leverage organic, endogenous materials in intracortical implants to enhance their biocompatibility as well as their functionality. In particular with respect to functionality, we assume that the spatiotemporal resolution of recorded neural signals may be significantly increased using this technology owing to the size ratios of these biohybrid microelectrodes compared to abiotic ones. Future investigations will therefore focus on the exploitation of the electrode density to further advance brain-computer interface technology.