bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review
Authors: Misra Shubham , Quinn Terence J. , Falcone Guido J. , Sharma Vijay K. , de Havenon Adam , Zhao Yize , Eldem Ece , French Jacqueline A. , Yasuda Clarissa Lin , Dawson Jesse , Liebeskind David S. , Kwan Patrick , Mishra Nishant K. 
Published: March 2023

AbstractBackground and purposeThe genetics of late seizure or epilepsy secondary to traumatic brain injury (TBI) or stroke are poorly understood. We undertook a systematic review to test the association of single‐nucleotide polymorphisms (SNPs) with the risk of post‐traumatic epilepsy (PTE) and post‐stroke epilepsy (PSE).MethodsWe followed methods from our prespecified protocol on PROSPERO to identify indexed articles for this systematic review. We collated the association statistics from the included articles to assess the association of SNPs with the risk of epilepsy amongst TBI or stroke patients. We assessed study quality using the Q‐Genie tool. We report odds ratios (OR) and hazard ratios with 95% confidence intervals (CIs).ResultsThe literature search yielded 420 articles. We included 16 studies in our systematic review, of which seven were of poor quality. We examined published data on 127 SNPs from 32 genes identified in PTE and PSE patients. Eleven SNPs were associated with a significantly increased risk of PTE. Three SNPs, TRMP6 rs2274924, ALDH2 rs671, and CD40 ‐1C/T, were significantly associated with an increased risk of PSE, while two, AT1R rs12721273 and rs55707609, were significantly associated with reduced risk. The meta‐analysis for the association of the APOE ɛ4 with PTE was nonsignificant (OR 1.8, CI 0.6–5.6).ConclusionsThe current evidence on the association of genetic polymorphisms in epilepsy secondary to TBI or stroke is of low quality and lacks validation. A collaborative effort to pool genetic data linked to epileptogenesis in stroke and TBI patients is warranted.
Beyond latitude: Temperature, productivity and thermal niche conservatism drive global body size variation in Odonata
Authors: Mähn Laura Anna , Hof Christian , Brandl Roland , Pinkert Stefan 
Published: March 2023

AbstractAimSo far, latitudinal body size clines have been discussed primarily in the context of thermoregulation, sensu Bergmann. However, body size patterns are ambiguous in ectotherms, and this heterogeneity remains poorly understood. We tested whether Bergmann's rule and the resource availability rule, which states that energetic requirements determine species body size, apply to damselflies and dragonflies (Odonata). Furthermore, we hypothesized that the contrasting effects of thermoregulation and resource availability (e.g., productivity) can obscure the overall gradient in body size variation.LocationGlobal.Time periodContemporary.Major taxa studiedOdonata.MethodsUsing data for 43% of all odonate species described so far, we tested our hypotheses in phylogenetically and spatially comparative analyses at assemblage and species levels. For the distribution data, we integrated expert range maps and ecoregional ranges based on all available occurrence records. To distinguish between long‐term and evolutionarily recent responses of environmental drivers in body size, we constructed a phylogenetically informed classification of all odonate species and decomposed the body size into its phylogenetic and specific components for our subset of species.ResultsWe documented a weak positive relationship between body length and latitude but found strong and contrasting effects for temperature between dragonflies and damselflies and consistent positive effects for productivity that explained 35–57% of body size variation. Moreover, we showed a strong phylogenetic signal in sized‐based thermoregulation that shaped the distribution of dragonflies, but not of damselflies.Main conclusionsWe concluded that temperature, productivity and conservatism in size‐based thermoregulation synergistically determine the distribution of ectotherms, while the taxon‐specific importance of these factors can lead to contrasting and weak latitude–size relationships. Our results reinforce the importance of body size as a determinant of species distributions and responses to climate change.
Mindfulness for people with chronic pain: Factors affecting engagement and suggestions for programme optimisation
Authors: Marikar Bawa Fathima L. , Mercer Stewart W. , Sutton Jane W. , Bond Christine M. 
Published: March 2023

AbstractIntroductionChronic pain is a common, multifactorial condition and pharmacological treatments have limited benefits. Mindfulness is a holistic approach that might be of value in the management of chronic pain. However, attrition rates from mindfulness‐based interventions are high and factors affecting engagement are unknown. The aim of this study was to inform the design of a mindfulness programme that would be accessible and acceptable for people with chronic pain.MethodsInterpretative phenomenological analysis of interview data from people with chronic pain who had taken part in an 8‐week mindfulness programme based on mindfulness‐based stress reduction revealed factors affecting engagement with and suggestions for tailoring the programme. Factors were grouped into physical, psychological and social domains. Further suggestions for tailoring the programme to address these factors were generated through a nominal group of healthcare professionals and a focus group with service users who had chronic pain.FindingsPhysical factors included disability and discomfort with some practices; psychological factors included expectations of the mindfulness programme and understanding the relationship between mindfulness and pain; and social factors included loneliness and support from others. The proposed modifications to the mindfulness programme supported by healthcare professionals and/or service users to address these are described in this paper.Public ContributionThis study involved public contributions at a number of stages. The University of Aberdeen Division of Applied Health Sciences Service User Group (who were members of the public with chronic pain) was involved in the design of the study. Patients with chronic pain recruited from general medical practice who took part in the mindfulness programme were interviewed on their experience of the programme. Patients with chronic pain who attended the mindfulness programme, and healthcare professionals with expertise in chronic pain and/or mindfulness, attended meetings to design a tailored mindfulness programme for people with chronic pain.
Development of al‐doped MgMn2O4‐based cathode materials for magnesium ion cells
Authors: Rosli Rosnadiya , Othman Othman , Harudin Nurhidayu Haji , Kufian Mohd Zieauddin , Mahat Annie Maria , Sonsudin Faridah , Supa'at Izlina , Osman Zurina 
Published: March 2023

AbstractMagnesium ion battery is an alternative for secondary battery instead of lithium ion battery due to its advantages of low cost, safety and environment friendly. Magnesium (Mg) is safer compared to lithium (Li) where it has high stability in contact of air and prevent the formation of dendrites during electrochemical cycling. The cathode materials of un‐doped MgMn2O4 and Al‐doped MgMn2‐xAlxO4, x = .01, .02, .03 were prepared using self‐propagating combustion method with triethanolamine fuel as a reducing agent. All samples (powder form) were annealed at 700˚C in 6 h based on the thermogravimetric analysis results. The samples were been characterized using X ray diffraction, field emission electron microscopy, energy‐dispersive X‐ray spectroscopy and high‐resolution transmission electron microscopy to study structural and morphological properties of the samples. Electrochemical properties of linear sweep voltammetry, cyclic voltammetry, and charge‐discharge capacity were performed in 1 M Magnesium Trifluoromethanesulfonate (MgTf2) with ratio 1:1 of ethylene carbonate: dimethyl ether electrolyte. The discharge capacity of magnesium ion cells using Al‐doped cathode material showed the improvement of 68% compared to the un‐doped sample.
Climate change and the displaced person: how vectors and climate are changing the landscape of infectious diseases among displaced and migrant populations
Authors: Choi Soo H. , Beer Jacob , Charrow Alexandra 
Published: March 2023

AbstractBackgroundAs the climate crisis grows, so does the global burden of displacement. Displacement, whether a direct or indirect consequence of natural disaster, can lead to dire health sequelae. Skin health is no exception to this, with dermatologic disease being a leading concern reported by those who care for displaced persons. Health professionals who provide dermatologic care for displaced persons benefit from understanding how climate change impacts the global profile of infectious agents.MethodsThis review was performed using PubMed and Google Scholar. Search terms included climate change, displaced person, internally displaced person, and refugee, as well as searches of infectious disease dermatology and the specific diseases of interest. Case reports, case series, reviews, and original research articles were included in this review. Non‐English studies were not included.ResultsIn this manuscript several key infectious agents were identified, and we discuss the skin manifestations and impact of climate change on cutaneous leishmaniasis, dengue, chikungunya, zika, malaria, pediculosis, cutaneous larva migrans, cholera, and varicella zoster.ConclusionsClimate change plays a significant role in the challenges faced by displaced persons, including their skin health. Among the many consequences of climate change is its altering of the ecological profile of infectious agents and vectors that impact displaced persons. Being familiar with this impact can improve dermatologic care for this vulnerable population.
Clinical application of a new method for determination of the erythrocyte sedimentation rate using the BC‐720 automated hematology analyzer
Authors: Shen Yimin , Liu Dongmei , Wang Yong , Cao Jun , Zhang Shuaishuai , Wen Hui , Dong Qiuqiu , Zheng Dong , Qiu Jun 
Published: March 2023

AbstractBackgroundThe erythrocyte sedimentation rate (ESR) is a nonspecific inflammatory indicator and is widely used in clinical diagnosis. Westergren is the gold standard method recommended by the International Committee for Standardization of Hematology (ICSH), but it is time‐consuming and inconvenient and has biosafety risks. A new alternate method for ESR (Easy‐W ESR) measurement was designed and integrated into the Mindray BC‐720 series automated hematology analyzer to meet the clinical needs of hematology laboratories for efficiency, safety, and automation. In this study, the performance of the new ESR method was evaluated based on the ICSH recommendations on modified and alternate ESR methods.MethodsMethodological comparisons using the BC‐720 analyzer, TEST 1, and the Westergren method were performed to assess repeatability, carryover, sample stability, reference range validation, factors influencing the ESR, and clinical applicability in rheumatology and orthopedics.ResultsThe correlation between the BC‐720 analyzer and the Westergren method was good (Y = 2.082 + 0.9869X, r = 0.9657, P > 0.0001, n = 342), carryover was <1%, the repeatability standard deviation was ≤1 mm/h, and the coefficient of variation (CV) was ≤5%. The reference range meets the manufacturer's claim. For rheumatology patients, the BC‐720 analyzer showed a good correlation with the Westergren method (Y = 1.021X–1.941, r = 0.9467, n = 149). For orthopedic patients, the BC‐720 analyzer also showed a good correlation with the Westergren method (Y = 1.037X + 0.981, r = 0.978, n = 97).ConclusionThis study verified the clinical and analytical performance of the new ESR method, indicating that the results are very similar to those obtained using the Westergren method.
Structural and functional insights into the ATP‐binding cassette transporter family in the corn planthopper, Peregrinus maidis
Authors: Wang Yu‐Hui , Klobasa William , Chu Fu‐Chyun , Huot Ordom , Whitfield Anna E. , Lorenzen Marcé 
Published: March 2023

AbstractThe corn planthopper, Peregrinus maidis, is an economically important pest of maize and sorghum. Its feeding behaviour and the viruses it transmits can significantly reduce crop yield. The control of P. maidis and its associated viruses relies heavily on insecticides. However, control has proven difficult due to limited direct exposure of P. maidis to insecticides and rapid development of resistance. As such, alternative control methods are needed. In the absence of a genome assembly for this species, we first developed transcriptomic resources. Then, with the goal of finding targets for RNAi‐based control, we identified members of the ATP‐binding cassette transporter family and targeted specific members via RNAi. PmABCB_160306_3, PmABCE_118332_5 and PmABCF_24241_1, whose orthologs in other insects have proven important in development, were selected for knockdown. We found that RNAi‐mediated silencing of PmABCB_160306_3 impeded ovary development; disruption of PmABCE_118332_5 resulted in localized melanization; and knockdown of PmABCE_118332_5 or PmABCF_24241_1 each led to high mortality within five days. Each phenotype is similar to that found when targeting the orthologous gene in other species and it demonstrates their potential for use in RNAi‐based P. maidis control. The transcriptomic data and RNAi results presented here will no doubt assist with the development of new control methods for this pest.
Community empowerment: A concept analysis
Authors: Kruahong Suratsawadee , Tankumpuan Thitipong , Kelly Kathleen , Davidson Patricia M. , Kuntajak Premgamon 
Published: March 2023

AbstractAimTo report an analysis of the concept of community empowerment.DesignConcept analysis.Data SourcesLiterature published in the CINAHL, PubMed, Scopus and Medline electronic databases from 2016 to 2022 were systematically searched from 30 July to 1 October 2022.MethodThe amended guideline from Walker and Avant's approach (2011) to concept analysis was performed in nine stages: choosing a concept, determining the purpose of analysis, identifying definitions of the concept, defining attributes, identifying a model case, identifying antecedents, identifying consequences, defining empirical referents and applying the concept to nursing practice.ResultsCommunity empowerment is a fundamental idea in health promotion that may assist communities in defining priorities, making choices, developing strategies and executing them to improve health and minimize inequalities in health. Community empowerment is an effective tool that advanced practice nurses (APNs) may employ to eliminate health inequities and promote community health.ConclusionThis concept analysis is one step towards broadening nurses' understanding of one of the ideas of health promotion. Additionally, the concept of community empowerment represents an opportunity for additional research in nursing that is applicable to communities.ImpactCommunity empowerment has served as a guiding paradigm for both theory and practice in health promotion. Also, it is recognized that social, economic and environmental elements have a direct effect on health status. However, community empowerment research in advanced nursing practices is limited. This paper will guide future nursing research on community empowerment that goes beyond involvement and engagement, for this is an effective strategy APNs can use to address health disparities and improve community health.
Abundance patterns of mammals across Russia explained by remotely sensed vegetation productivity and snow indices
Authors: Razenkova Elena , Dubinin Maxim , Pidgeon Anna M. , Hobi Martina L. , Zhu Likai , Bragina Eugenia V. , Allen Andrew M. , Clayton Murray K. , Baskin Leonid M. , Coops Nicholas C. , Radeloff Volker C. 
Published: March 2023

AbstractAimPredicting biodiversity responses to global changes requires good models of species' distributions. Both environmental conditions and human activities determine population density patterns. However, quantifying the relationship between wildlife population densities and their underlying environmental conditions across large geographical scales has remained challenging. Our goal was to explain the abundances of mammal species based on their response to several remotely sensed indices including the Dynamic Habitat Indices (DHIs) and the novel Winter Habitat Indices (WHIs).LocationRussia, the majority of regions.TaxonEight mammal species.MethodsWe estimated average population densities for each species across Russia from 1981 to 2010 from winter track counts. The DHIs measure vegetative productivity, a proxy for food availability. Our WHIs included the duration of snow‐free ground, duration of snow‐covered ground and the start, end and length of frozen season. In models, we included elevation, climate conditions, human footprint index. We parameterized multiple linear regression and applied best‐subset model selection to determine the main factors influencing population density.ResultsThe DHIs were included in some of the top‐twelve models of every species, and in the top model for moose, wild boar, red fox and wolf, so they were important for species at all trophic levels. The WHIs were included in top models for all species except roe deer, demonstrating the importance of winter conditions. The duration of frozen ground without snow and the end of frozen season were particularly important. Our top models performed well for all the species (R2adj 0.43–0.87).Main ConclusionsThe combination of the DHIs and the WHIs with climate and human‐related variables resulted in high explanatory power. We show that vegetation productivity and winter conditions are key drivers of variation in population density of eight species across Russia.
Long‐term care in EU policy 1999‐2022: women's responsibility, migrants' work?
Authors: Zacharenko Elena 
Published: March 2023

AbstractAs the population of the European Union (EU) is ageing and its working‐age population shrinking, concerns are rising about how the growing demand for long‐term care (LTC) will be met. Since unpaid care, provided mainly by women, is increasingly scarce, some EU states are becoming dependent on migrant labour for the functioning of their elder care systems. To address the growing deficit of care in the EU, the European Commission put forward a European Care Strategy, for the first time proposing a stand‐alone policy on LTC. This followed on from a Commission proposal for a new strategy on migration, calling for labour migrants to be proactively attracted to work in the EU's care sector. As the (lack of) availability of LTC is increasingly shaping EU policy, it is timely to investigate what its impact is on key policy areas, such as gender equality, social and migration policies.
Interpopulation variation of behavioural and morphological traits that affect downstream displacement of the juvenile white‐spotted charr Salvelinus leucomaenis
Authors: Yamada Hiroyuki , Wada Satoshi 
Published: March 2023

AbstractDownstream displacement, the passive downstream dispersal of riverine organisms, can generate evolutionary pressures that selectively remove susceptible individuals from upstream habitats. These evolutionary pressures may accumulate over time in fish populations situated upstream of a tall check dam that displaced fish are unable to swim over and can be diluted by the homing of displaced individuals in the absence of such barriers. Here, we conducted interpopulation comparisons between above‐dam and unrestricted open‐stream populations of the juvenile white‐spotted charr Salvelinus leucomaenis to test the hypothesis that above‐dam juveniles possess more advantageous traits that reduce downstream displacement than open‐stream juveniles. We focused on sedentary behaviour and body depth, both of which are known to affect downstream displacement. Interpopulation comparisons revealed that juveniles from above‐dam populations were consistently more sedentary than those from open‐stream populations. On the other hand, there were no systematic differences in body depth between above‐dam and open‐stream populations. These results are consistent with the evolution of behaviours in above‐dam populations that inhibit downstream displacement. However, several other factors could explain the results obtained and further studies will be needed to confirm the presence of behavioural evolution in our study system.
Effect of plasma‐activated water generated by surface DBD on inactivation of pathogens Pseudomonas tolaasii and Lecanicillium fungicola and enhancement of storage quality of button mushroom
Authors: Pourbagher Roghayeh , Abbaspour‐Fard Mohammad Hossein , Sohbatzadeh Farshad , Rohani Abbas , Pourbagher Maryam 
Published: March 2023

AbstractPseudomonas tolaasii and Lecanicillium fungicola are the bacterial and fungal pathogen that causes brown spots and dry bubble diseases and spoilage of fresh mushroom. The objective of this study was to consider the efficacy of plasma‐activated water (PAW) on the inactivation of P. tolaasii and L. fungicola and storage quality of button mushroom. Button mushrooms were immersed for 10 min in PAW generated by four types of plasma feeding gas at activation times 5, 10, 15, and 20 min, designated PAW‐5, PAW‐10, PAW‐15, and PAW‐20, respectively. The results indicated that the bacteria and fungi growth was controlled by PAW treatment through 21 days of post‐harvest storage. The lowest bacterial and fungal population was 3.6‐log CFU g−1 and 4.7‐log CFU g−1 after treatment with PAW‐20 generated by hydrogen peroxide bubbled with air (H2O2‐air), which was significantly lower than that of control (6.57 and 7.49 log CFU g−1) or soaking in distilled water (7.65 and 8.57 log CFU g−1), respectively. The plasma created by H2O2‐air gas formed the highest concentration of H2O2, NO2−, and NO3− species in PAW. The findings of water friendship and firmness showed that immersion in PAW could delay the softness of the mushroom. In addition, treatment with PAW significantly inactivated polyphenol oxidase (PPO) and peroxidase (POD) enzymes. Meanwhile, significant changes were registered in the color, antioxidant activity and phenolic content of mushrooms treated with PAW and the control groups. Thus, PAW treatment may be considered as an alternative method for fresh keeping of button mushroom.Practical ApplicationsChemical, radiation, and physical methods (modified‐atmosphere packaging and refrigeration) used to increase the shelf‐life of edible mushrooms cause discoloration, a decrease in nutritional value, and tastelessness. Activated water technology with cold plasma is one of the non‐thermal and environmentally‐friendly methods that, while solving the mentioned problems, ensures food safety without significant impact on sensory or nutritional characteristics. The results presented in this study introduce plasma‐activated water as an effective method for inactivating disease‐causing pathogens and lesions in button mushrooms. This technology is a suitable alternative method for the disinfection of edible mushrooms due to maintaining freshness and physicochemical characteristics as well as inhibiting the activity of browning enzymes and pathogenic microorganisms.