bluuebunny/crossref_metadata_2025_split huggingface dataset:
CFD-Based Simulation for the Stability of Floating Solar Arrays
Authors: Arora Prince , Prasad Patel Badri , Ahmad Suhail , Jain Arvind Kumar , Joe Joe C. S. , Aggarwal Pratham 
Published: September 2023

Abstract
Floating solar energy technology, among other renewable energy, is growing exponentially, owing to reduced water evaporation from the water body and much less land requirement. Floating Photovoltaic (FPV) panels can be installed in any water body, viz. lakes, balancing reservoirs, backwaters, dam reservoirs etc. However, the FPV system is very complex due to the involvement of multiple types of equipment to name a few: - floats, anchoring & mooring system, solar modules, string monitoring unit, power conditioning units, LV switchgear, cables, inverter transformer, AC & DC cables, lightning arrestors etc. Further, this complexity increases during different project phases (erection, installation, towing of arrays, commissioning etc.), with variable water depth due to bathymetry and frequent water level changes in the case of a dam reservoir. In addition to that, system connection must be flexible with modular installation. Worldwide, FPV is gaining commercial interest due to its low LCOE and researcher interest due to its vast research potential.
One significant challenge in the design, engineering & installation of FPV is the unavailability of international codes & standards. The only recommended practice for FPV is DNVGL-RP-0584, which still requires many improvements. While designing the system, most industries follow the extreme wind conditions applicable for buildings but do not precisely describe the situation specific to floating solar. In the recent past, one of the floating solar parks collapsed due to a strong wind gust[1].
A solar array is first modelled in the present work, and its aerodynamics is investigated through CFD in ANSYS FLUENT. A parametric study is then carried out with the variable inclination angle of solar panels. The wind loads are then compared with a standard analytical approach considering the wind pressure acting on the projected area. An optimized size of the solar array is recommended based on CFD loads at a particular inclination angle of the solar panel. Such a study helps design an FPV park without the code.
The Relationship Between Lower-Body Force–Time Variables and Skating Performance in Female Ice Hockey Players
Authors: Geneau Mary C. , Tsai Ming-Chang , Agar-Newman Dana , Geneau Daniel J. , Klimstra Marc , James Lachlan P. 
Published: September 2023

Purpose: Ice hockey is a team invasion sport characterized by repeated high-intensity skating efforts, technical and tactical skill, physical contact, and collisions requiring considerable levels of muscular strength. The purpose of this study was to evaluate the relationships between lower-body vertical force–time metrics and skating qualities in subelite female ice hockey players. Methods: A cross-sectional cohort design was employed utilizing 14 athletes (body mass = 66.7 [1.8] kg; height = 171.6 [6.2] cm; age = 21.1 [1.7] y). The relationships between metrics of lower-body strength collected from a drop jump, squat jump, countermovement jump, loaded countermovement jump, and an isometric squat and 4 skating qualities collected from a linear sprint, repeated sprint test, and a multistage aerobic test were evaluated. Results: The regression models revealed a positive relationship between relative peak force in the isometric squat and skating multistage aerobic test performance (r2 = .388; P = .017) and a positive relationship between repeated-sprint ability and eccentric mean force during the loaded countermovement jump (r2 = .595; P = .001). No significant relationships were observed between strength metrics and skating acceleration or maximal velocity. Conclusions: These data suggest that skating ability is most affected by relative isometric strength in female ice hockey players. It is recommended that practitioners focus training on tasks that improve relative force output. It is also recommended that isometric relative peak force be used as a monitoring metric for this cohort.
Draft genomes of
Lactobacillus delbrueckii
and
Klebsiella pneumoniae
coexisting within a female urinary bladder
Authors: London Laricca Y. , Lim Chae Hee , Modliszewski Jennifer L. , Siddiqui Nazema Y. , Sysoeva Tatyana A. 
Published: September 2023

ABSTRACT

Here, we present the draft genome sequences of
Lactobacillus delbrueckii
and
Klebsiella pneumoniae
, both isolated from the urinary bladder of an asymptomatic post-menopausal female patient with a diagnosis of recurrent urinary tract infections. These genomes will facilitate analyses of interbacterial interactions in the urinary microbiome.
In vitro
activity of cefiderocol against comparators (ceftazidime-avibactam, ceftazidime-avibactam/ aztreonam combination, and colistin) against clinical isolates of meropenem-resistant
Klebsiella pneumoniae
from India
Authors: Borde Kalyani , Kareem M. A. , Sharma Ratna Mani , Dass S. Manick , Ravi Vedantham , Mathai Dilip 
Published: September 2023

ABSTRACT

Cefiderocol (FDC), a novel siderophore drug, is active against Gram-negative bacteria producing carbapenemases, including metallo-beta-lactamases. The objective of this study is to compare the
in vitro
activity of FDC with ceftazidime-avibactam (CZA), CZA/aztreonam (AT) combination, and colistin (CST), in clinical isolates of meropenem-resistant (MER-R)
Klebsiella pneumoniae
. From the 2,052 clinical specimens submitted for culture testing, 245
K
.
pneumoniae
isolates were recovered within a 6-month period in 2021. One hundred three non-duplicate, non-outbreak, MER-R (minimum inhibitory concentration, MIC >4 µg/mL) strains were included in the study. Identification and susceptibility were performed using VITEK-2 (bioMérieux). Meropenem-susceptible isolates (
n
= 10) served as controls. For FDC, broth microdilution (BMD) was performed after in-house standardization. Disk diffusion (Liofilchem, Italy) and broth microdilution (ComASP, STC, Liofilchem, Italy) were used for susceptibility testing of CZA and CST, respectively. Synergy testing for CZA and AT was performed using disk approximation method. CLSI breakpoints were used for the interpretation of the results. For FDC, MIC
50
and MIC
90
were 2 and 8 µg/mL, respectively. A total of 80% of isolates were susceptible to FDC, 26.2% of isolates were susceptible to CZA, synergy testing with CZA/AT was positive for 74 (72%) of the isolates, and 89.3% were intermediate to CST. Nine (8.7%) were susceptible only to FDC. FDC is active
in vitro
against MER-R
K. pneumoniae
>CZA/AT > CZA > CST
,
as observed in this study, applying CLSI criteria. Clinico-microbiological studies should be performed to assess the clinical efficacy of this novel drug in this region with a high prevalence of carbapenem resistance among Gram-negative organisms.

Importance

Management of infections with multi-drug resistant
Klebsiella pneumoniae
is a major challenge in hospital settings, with few treatment options. In this study, the authors aim to assess the
in vitro
susceptibility of these clinical isolates to cefiderocol, a novel siderophore. Comparators are colistin, ceftazidime-avibactam, and ceftazidime-avibactam/aztreonam synergy, which are currently available options for treatment in this region. Baseline-resistance rates against cefiderocol are higher than those in the previously published studies, with MIC50 and MIC90 at 2 and 8 µg/mL, respectively.
Composition of Phenocrysts in Lamproites of Gaussberg Volcano, East Antarctica
Authors: Migdisova N. A. , Sushchevskaya N. M. , Portnyagin M. V. , Shishkina T. A. , Kuzmin D. V. , Batanova V. G. 
Published: September 2023

Abstract—This paper presents numerous new data on the geochemical composition of olivine, clinopyroxene, and leucite phenocrysts, as well as spinel inclusions in olivine and quench glass from lamproites of Gaussberg volcano (East Antarctica). Most of the olivine phenocrysts in the Gaussberg lamproites are high Mg varieties (Fo89–91) with elevated Ni contents (up to 4900 ppm) and high Ni/Co ratios. According to data of about 320 clinopyroxene analyses, two groups of diopsidic phenocrysts have been established. Group I consists mainly of high-Mg varieties (Mg#>80), while group II clinopyroxenes are less magnesian (Mg# 52–80). The main difference between the clinopyroxenes of the two groups is the elevated contents of Al2O3, FeO and reduced TiO2, Cr2O3, and NiO in the compositions of group II compared to group I, as well as different contents of trace elements, which may reflect their crystallization from different types of primary melts. According to the study of ~550 grains of leucite phenocrysts in the Gaussberg lamproites, it was shown that they correspond to the ideal stoichiometry of leucite K[AlSi2O6] and are enriched in Na2O (0.05–0.35 wt %), but depleted in K2O (19.9–20.9 wt %) compared to leucites from lamproites of other provinces. The BaO content reaches 0.3 wt %, SrO –0.04 wt %. The iron content in most leucite phenocrysts varies within 0.7–1.2 wt % Fe2O3, but some grains have the low Fe2O3 contents (<0.5 wt %). In leucite microlites of the groundmass and rims of phenocrysts, the Fe2O3 content can reach 2.4 wt %, which may indicate more oxidized conditions at lava eruption. Based on the study of natural samples, existing experimental data and numerical models, the order and conditions of crystallization of the Gaussberg lamproites were obtained. Crystallization proceeded in the following order: chromian spinel → chromian spinel + olivine → olivine + leucite (± chromian spinel) → olivine + leucite + clinopyroxene (± chromian spinel). The near-liquidus assemblage represented by high-Mg olivine phenocrysts with inclusions of Cr-spinel was formed in the temperature range from 1180 to 1250°C. Further crystallization of the melt with the formation of an association of olivine+leucite+clinopyroxene phenocrysts could occur at pressures below 2 GPa and temperatures of 1070–1180°C, corresponding to the presence of water in the magmatic system. Estimates of the redox conditions of crystallization of lamproites obtained using different oxybarometers vary in a wide range from QFM-0.5 to QFM+2.3. The elevated Ni contents in liquidus olivines of Gaussberg indicate the high nickel contents in the source. It is shown that the formation of ultra-alkaline magmas in the Gaussberg volcano area is likely related to melting of the continental lithosphere, which was heterogeneous and included both the peridotite mantle and hydrous pyroxenite fragments.
Interplay between chronic widespread pain and lifestyle factors on the risk of type 2 diabetes: longitudinal data from the Norwegian HUNT Study
Authors: Marcuzzi Anna , Caceres-Matos Rocio , Åsvold Bjørn Olav , Gil-Garcia Eugenia , Nilsen Tom I L , Mork Paul Jarle 
Published: September 2023

IntroductionChronic widespread pain (CWP) and diabetes commonly co-occur; however, it is unclear whether CWP infers an additional risk for diabetes among those with known risk factors for type 2 diabetes. We aimed to examine if CWP magnifies the effect of adverse lifestyle factors on the risk of diabetes.Research design and methodsThe study comprised data on 25 528 adults in the Norwegian HUNT Study without diabetes at baseline (2006–2008). We calculated adjusted risk ratios (RRs) with 95% CIs for diabetes at follow-up (2017–2019), associated with CWP and body mass index (BMI), physical activity, and insomnia symptoms. The relative excess risk due to interaction (RERI) was calculated to investigate the synergistic effect between CWP and adverse lifestyle factors.ResultsCompared with the reference group without chronic pain and no adverse lifestyle factors, those with BMI ≥30 kg/m2with and without CWP had RRs for diabetes of 10.85 (95% CI 7.83 to 15.05) and 8.87 (95% CI 6.49 to 12.12), respectively; those with physical activity <2 hours/week with and without CWP had RRs for diabetes of 2.26 (95% CI 1.78 to 2.88) and 1.54 (95% CI 1.24 to 1.93), respectively; and those with insomnia symptoms with and without CWP had RRs for diabetes of 1.31 (95% CI 1.07 to 1.60) and 1.27 (95% CI 1.04 to 1.56), respectively. There was little evidence of synergistic effect between CWP and BMI ≥30 kg/m2(RERI=1.66, 95% CI −0.44 to 3.76), low physical activity (RERI=0.37, 95% CI −0.29 to 1.03) or insomnia symptoms (RERI=−0.09, 95% CI −0.51 to 0.34) on the risk of diabetes.ConclusionsThese findings show no clear interaction between CWP and adverse lifestyle factors on the risk of diabetes.
Association of sleep disorders with asthma: a meta-analysis
Authors: Liu Xueqian , Hong Cheng , Liu Zhiyu , Fan Lihua , Yin Moqing , Chen Yunhu , Ren Xiang , Gu Xuefang 
Published: September 2023

BackgroundAnimal experiments and clinical trials have revealed a potential relationship between sleep disorders and asthma. However, the associations between these factors remain unclear.Material and methodsWe searched PubMed, Embase, Web of Science and Cochrane Library databases for eligible studies published before 30 December 2022. Studies investigating the association between sleep disorders (insomnia, poor sleep quality and insufficient sleep time) and asthma were selected. Sleep disorders were assessed using questionnaires, interviews, or medical records. Asthma was diagnosed based on medical history and drug use. The Newcastle-Ottawa Scale and the Agency for Healthcare Research and Quality checklist were employed for quality assessment. We used OR with 95% CI as the effect measures and forest plots to display the results. Heterogeneity was evaluated usingI2statistics and subgroup analyses were performed for bias analysis. Publication bias was evaluated using the funnel plots and Egger’s test.ResultsTwenty-three studies were included in the primary analysis, which suggested a positive association between sleep disorders and asthma (OR: 1.38, 95% CI 1.10 to 1.74). Subgroup analyses were conducted according to the study design, age, family history of asthma and type of sleep disorders. We did not find any association between sleep disorders and asthma in children aged ˂12 years (OR: 1.13, 95% CI 0.97 to 1.32). The association was insignificant in studies where the family history of asthma was adjusted for (OR: 1.16, 95% CI 0.94 to 1.42). Funnel plot and Egger’s test indicated a significant publication bias.ConclusionSleep disorders are associated with an increased prevalence and incidence of asthma. However, the quality of the evidence was low because of potential biases.PROSPERO registration numberCRD42023391989.
Preterm birth, birth weight, infant weight gain and their associations with childhood asthma and spirometry: a cross-sectional observational study in Nairobi, Kenya
Authors: Meme Helen , Amukoye Evans , Bowyer Cressida , Chakaya Jeremiah , Dobson Ruaraidh , Fuld Jonathan , Gray Cindy M , Kiplimo Richard , Lesosky Maia , Mortimer Kevin , Ndombi Amos , Obasi Angela , Orina Fred , Quint Jennifer K , Semple Sean , West Sarah E , Zurba Lindsey , Devereux Graham 
Published: September 2023

BackgroundIn sub-Saharan Africa, the origins of asthma and high prevalence of abnormal lung function remain unclear. In high-income countries (HICs), associations between birth measurements and childhood asthma and lung function highlight the importance of antenatal and early life factors in the aetiology of asthma and abnormal lung function in children. We present here the first study in sub-Saharan Africa to relate birth characteristics to both childhood respiratory symptoms and lung function.MethodsChildren attending schools in two socioeconomically contrasting but geographically close areas of Nairobi, Kenya, were recruited to a cross-sectional study of childhood asthma and lung function. Questionnaires quantified respiratory symptoms and preterm birth; lung function was measured by spirometry; and parents were invited to bring the child’s immunisation booklet containing records of birth weight and serial weights in the first year.Results2373 children participated, 52% girls, median age (IQR), 10 years (8–13). Spirometry data were available for 1622. Child immunisation booklets were available for 500 and birth weight and infant weight gain data were available for 323 and 494 children, respectively. In multivariable analyses, preterm birth was associated with the childhood symptoms ‘wheeze in the last 12 months’; OR 1.64, (95% CI 1.03 to 2.62), p=0.038; and ‘trouble breathing’ 3.18 (95% CI 2.27 to 4.45), p<0.001. Birth weight (kg) was associated with forced expiratory volume in 1 s z-score, regression coefficient (β) 0.30 (0.08, 0.52), p=0.008, FVC z-score 0.29 (95% CI 0.08 to 0.51); p=0.008 and restricted spirometry, OR 0.11 (95% CI 0.02 to 0.78), p=0.027.ConclusionThese associations are in keeping with those in HICs and highlight antenatal factors in the aetiology of asthma and lung function abnormalities in sub-Saharan Africa.
UK and Ireland Joint Advisory Group (JAG) consensus statements for training and certification in diagnostic endoscopic ultrasound (EUS)
Authors: El Menabawey Tareq , McCrudden Raymond , Shetty Dushyant , Hopper Andrew D , Huggett Matthew T , Bekkali Noor , Carroll Nicholas R , Henry Elaine , Johnson Gavin J , Keane Margaret G , Love Mark , McKay Colin J , Norton Sally , Oppong Kofi , Penman Ian , Ramesh Jayapal , Ryan Barbara , Siau Keith , Nayar Manu 
Published: September 2023

Background and aimsInternational endoscopy societies vary in their approach for credentialing individuals in endoscopic ultrasound (EUS) to enable independent practice; however, there is no consensus in this or its implementation. In 2019, the Joint Advisory Group on GI Endoscopy (JAG) commissioned a working group to examine the evidence relating to this process for EUS. The aim of this was to develop evidence-based recommendations for EUS training and certification in the UK.MethodsUnder the oversight of the JAG quality assurance team, a modified Delphi process was conducted which included major stakeholders from the UK and Ireland. A formal literature review was made, initial questions for study were proposed and recommendations for training and certification in EUS were formulated after a rigorous assessment using the Grading of Recommendation Assessment, Development and Evaluation tool and subjected to electronic voting to identify accepted statements. These were peer reviewed by JAG and relevant stakeholder societies before consensus on the final EUS certification pathway was achieved.Results39 initial questions were proposed of which 33 were deemed worthy of assessment and finally formed the key recommendations. The statements covered four key domains, such as: definition of competence (13 statements), acquisition of competence (10), assessment of competence (5) and postcertification mentorship (5). Key recommendations include: (1) minimum of 250 hands-on cases before an assessment for competency can be made, (2) attendance at the JAG basic EUS course, (3) completing a minimum of one formative direct observation of procedural skills (DOPS) every 10 cases to allow the learning curve in EUS training to be adequately studied, (4) competent performance in summative DOPS assessments and (5) a period of mentorship over a 12-month period is recommended as minimum to support and mentor new service providers.ConclusionsAn evidence-based certification pathway has been commissioned by JAG to support and quality assure EUS training. This will form the basis to improve quality of training and safety standards in EUS in the UK and Ireland.
Interplay between diet, circulating indolepropionate concentrations and cardiometabolic health in US populations
Authors: Hu Yang , Li Jun , Wang Biqi , Zhu Lu , Li Yanping , Ivey Kerry L , Lee Kyu Ha , Eliassen A Heather , Chan Andrew , Huttenhower Curtis , Hu Frank B , Qi Qibin , Rimm Eric B , Sun Qi 
Published: September 2023

ObjectivesTo identify indolepropionate (IPA)-predicting gut microbiota species, investigate potential diet–microbiota interactions, and examine the prospective associations of circulating IPA concentrations with type 2 diabetes (T2D) and coronary heart disease (CHD) risk in free-living individuals.DesignWe included 287 men from the Men’s Lifestyle Validation Study, a substudy of the Health Professionals Follow-Up Study (HPFS), who provided up to two pairs of faecal samples and two blood samples. Diet was assessed using 7-day diet records. Associations between plasma concentrations of tryptophan metabolites and T2D CHD risk were examined in 13 032 participants from Nurses’ Health Study (NHS), NHSII and HPFS.ResultsWe identified 17 microbial species whose abundance was significantly associated with plasma IPA concentrations. A significant association between higher tryptophan intake and higher IPA concentrations was only observed among men who had higher fibre intake and a higher microbial species score consisting of the 17 species (p-interaction<0.01). Dietary and plasma concentrations of tryptophan and most kynurenine pathway metabolites were positively associated with T2D risk (HRQ5 vs Q1ranged from 1.17 to 1.46) while a significant inverse association was found for IPA (HRQ5 vs Q1(95% CI) 0.70 (0.56 to 0.88)). No associations were found in CHD for any plasma tryptophan metabolites.ConclusionsSpecific microbial species and dietary fibre jointly predicted significantly higher circulating IPA concentrations at higher tryptophan intake. Dietary and plasma tryptophan, as well as its kynurenine pathway metabolites, demonstrated divergent associations from those for IPA, which was significantly predictive of lower risk of T2D.
Unravelling interobserver variability in gastrointestinal glandular neoplasia: a contemporary study of US and Korean pathologists
Authors: Pacheco Richard R , Kim Hyunki , Choi Won-Tak , Kook Myeong-Cherl , Cho Mee-Yon , Karamchandani Dipti M , Lee Michael J , Kim Baek-Hui , Lee Sung-Hak , Yang Zhaohai , Kim Jihun , Lagana Stephen M , Lee Hwajeong 
Published: September 2023

AimsInterobserver variability in the assessment of gastric neoplasia biopsies between most Western and Eastern (predominantly represented by Japanese in the literature) pathologists has been documented. It is unknown if such variability exists between the US and Korean pathologists in the current era.MethodsTen gastrointestinal (GI) pathologists from the USA (n=5) and South Korea (n=5) evaluated 100 scanned images of gastric (n=50) and colorectal (n=50) neoplasia biopsies and answered multiple questionnaires. Consensus was defined as the answer chosen by the majority. Cohen’s (κc) and Fleiss’ kappa (κf) values were calculated between the consensus of the two groups and among the raters, respectively.ResultsBoth groups reached a consensus in the majority of cases (74%–100%) with slight to perfect intergroup (κc=0.049–1.000) and no to substantial intragroup (κf=−0.083 to 0.660) agreements. For gastric neoplasia, Korean pathologists relied heavily on cytoarchitectural atypia, whereas the US pathologists focused on stromal invasion when diagnosing adenocarcinoma. For colorectal neoplasia, the Korean pathologists identified concurrent intramucosal carcinoma when diagnosing invasive adenocarcinoma, while the presence of desmoplasia was a prerequisite for the diagnosis of invasive adenocarcinoma for the US pathologists.ConclusionsFor GI neoplasia biopsy interpretation, the diagnostic approach of Korean pathologists is similar to that of Eastern/Japanese pathologists. Consensus outperformed kappa statistics in capturing the magnitude of inter-rater and intergroup reliability, highlighting the potential benefit of consensus meetings to decrease the gap between Western and Eastern diagnostic approaches.