bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-traumatic brain injury glioma: Characteristics, report of 2 cases report and literature review
Authors: Chen Kui , Andrade-Barazarte Hugo , Liang Wenjia , Zhu Qingyun , Guo Haixing , Li Yanxin , Li Haichun , Qian Rongjun 
Published: December 2022

Background:
Traumatic brain injury (TBI) as a pathogenetic factor in glioma remains controversial, and currently there is still no clear mechanism behind post-TBI glioma. Thus, we provide two case reports of post-TBI glioma contributing power to this research, and we provide a summary of the mechanisms of post-TBI glioma through literature review.

Methods:
We report two cases of brain gliomas that developed in the scar of a previous brain trauma. Both patients were male and both had suffered prior traumatic brain injuries (time interval 10–20 years), and postoperative pathological findings reported glioblastoma and WHO grade III glioma, respectively.

Results:
These two cases further support the association of between traumatic brain injury and gliomas development.

Conclusion:
Although the epidemiological investigation between TBI and glioma is still controversial, there are still some important aspects here that can determine the possibility between TBI and gliomagenesis. Besides, we found that the reparative response of neural stem cells and the dysregulation of inflammatory cells are timportant theories of the mechanism of post-TBI glioma.
One filter may be enough for duplicate inferior vena cava filter implantation in patients with deep venous thrombosis: Two cases report
Authors: Li Tao , Wang Qi , Wang Wei , Yang Jun , Dong Shuilin 
Published: December 2022

Background:
Duplicate inferior vena cava (IVC) is an uncommon congenital malformation, but should be treated carefully under the circumstances of deep venous thrombosis (DVT). However, there is a paucity of clinical guidance on this situation.

Methods:
Duplicate IVC was diagnosed based on the imaging examination that revealed the dual IVC. Deep venous thrombosis was diagnosed by Compression Doppler ultrasonography of both lower extremities with the high-elevated D-dimer. Retrievable IVC filters were implanted to prevent massive and fatal pulmonary embolism. Appropriate anticoagulation therapy was also performed.

Results:
Two retrievable filters were successfully implanted and retrieved in two patients with deep venous thrombosis and duplicate inferior vena cava, respectively. During further follow-up, no adverse event was reported.

Conclusion:
Comprehensive imaging examination might contribute to the diagnosis of duplicate IVC, especially when individual conditions were limited. The position above the confluence of bilateral IVCs might be an appropriate suprarenal retrievable filter insertion location. To deal with different types of dual IVC anatomy, different strategies should be taken into consideration.
The effect and safety of low-dose Tripterygium wilfordii in patients with type 2 diabetic nephropathy: A meta-analysis
Authors: Chen Yixuan , Lu Meiqi , Feng Yiting , Gao Qing 
Published: December 2022

Background:This review aims to assess the efficacy and safety of low-doseTripterygium wilfordiiHook F (TWHF) in treating type 2 diabetic nephropathy (DN) and provide high-level evidence supporting its normalized application.Methods:Seven electronic databases were queried to locate trials that qualify. Randomized controlled trials (RCTs) about low-dose TWHF long-term treatment of type 2 DN are included. After data extraction and quality evaluation of the clinical studies that met the inclusion criteria, a meta-analysis was performed using RevMan 5.4 and Stata 14.Results:A total of 23 RCTs were included. For the patients in the trial group, the effective rate [confidence interval (CI), odd ratio] [odd ratio = 1.38, 95% CI (1.22–1.56),P < .001], albumin [standard mean difference (SMD) = 0.58, 95% CI (0.18–0.98),P = .004], 24-hour urine total protein [SMD = −1.329, 95% CI = (−1.647 to −1.012),P < .001], serum creatinine [SMD = −0.64, 95% CI = (−0.86 to −0.31),P < .001], and the untoward effect [RR = 2.43 95% CI = (1.23–4.82),P = .01] were significantly higher than those in the control group. However, in white blood cell [Weighted mean difference = −0.27, 95% CI (−0.54 to 0.01),P = .06] and blood urea nitrogen [Weighted mean difference = −0.11, 95% CI (−0.42 to 0.21),z = 0.67,P = .50], none of the differences were significant compared with the control group.Conclusion:This suggests that low-dose TWHF positively affects patients with type 2 DN after a long course of treatment. Although there are some side effects, symptoms can improve after medication suspension or symptomatic treatment. Limited by the methodological quality of the included studies, this conclusion needs to be verified by more large-sample RCTs with rigorous design and long-term follow-up.
The optimal dose of intravenous dexamethasone in peripheral nerve blocks: A protocol for systematic review and meta-analysis
Authors: Wu Yinglong , Wei Yiyong , Zhang Donghang 
Published: December 2022

Background:
Although intravenous dexamethasone prolongs the duration of analgesia for peripheral nerve blocks (PNB), the optimal dose of dexamethasone is not yet determined. This protocol aims to compare the analgesic effects of different doses of intravenous dexamethasone on PNB.

Methods:
We will search PubMed, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and Web of Science to identify randomized controlled trials that compared the effects of different doses of intravenous dexamethasone for PNB. The duration of analgesia will be defined as the primary outcome. Secondary outcomes will include pain scores, analgesics consumption >48 hours, and the incidence of adverse effects. RevMan 5.3 software will be used for data analysis.

Results:
This study will explore the optimal dose of intravenous dexamethasone for the prolongation of analgesia in PNB.

Conclusion:
The results of this study will provide evidence for the dose selection of intravenous dexamethasone in PNB.
Comparative study of fractional flow reserve and diastolic pressure ratio using a guidewire with a sensor for measuring intravascular pressure
Authors: Kojima Hiroki , Ishii Hideki , Tanaka Akihito , Funakubo Hiroshi , Kato Toshiaki , Shimbo Yusaku , Kawamiya Toshiki , Kuwatsuka Yachiyo , Ando Masahiko , Murohara Toyoaki 
Published: December 2022

Purpose:
This study aimed to evaluate the correlation and diagnostic agreement between diastolic pressure ratio (dPR) and fractional flow reserve (FFR) in a Japanese real-world setting.

Design:
Prospective multicenter observational study

Methods:
This study included 100 patients with intermediate coronary artery stenosis at 4 Japanese hospitals. For these lesions, FFR and dPR were measured using a guidewire with a sensor and a monitor to measure intravascular pressure. The correlation and diagnostic agreement between FFR and dPR were assessed. When both FFR and dPR were negative or positive, the results were considered to be concordant. When one was positive and the other was negative, the result was regarded as discordant (positive discordance, FFR > 0.80 and dPR ≤ 0.89; negative discordance, FFR ≤ 0.80 and dPR > 0.89).

Results:
Overall, the FFR and dPR were well-correlated (R = 0.841). FFR and dPR were concordant in 89% of cases (concordant normal, 43%; concordant abnormal, 46%) and discordant in 11% (positive discordance, 7%; negative discordance, 4%). No significant difference was observed in the rate of concordant results between patients with and without diabetes mellitus. The diagnostic concordance rate was significantly different among the 3 coronary arteries (right coronary artery, 93.3%; left anterior descending artery, 93.2%; and left circumflex artery, 58.3%; P = .001). Additionally, the rate of concordant results tended to be higher when using intravenous administration of adenosine than when using intracoronary bolus injection of nicorandil (adenosine, 95.1%; nicorandil, 84.7%; P = .103).

Conclusion:
We found that dPR was highly correlated with FFR, and diagnostic discordance was observed in 11% of the lesions. Several factors, including lesion location and medication for hyperemia, may cause the diagnostic discordance between dPR and FFR.
Identification of hub genes related to Duchenne muscular dystrophy by weighted gene co-expression network analysis
Authors: Wei Yanning , Su Qisheng , Li Xiaohong 
Published: December 2022

Background:
The study was aimed to analyze the potential gene modules and hub genes of Duchenne muscular dystrophy (DMD) by weighted gene co-expression network analysis.

Methods:
Based on the muscular dystrophy tissue expression profiling microarray GSE13608 from gene expression omnibus, gene co-expression modules were analyzed using weighted gene co-expression network analysis, gene modules related to DMD were screened, gene ontology and Kyoto encyclopedia of genes and genomes enrichment analyses were performed, and signature genes in the modules were screened. The protein–protein interaction network was constructed through Cytoscape, and hub genes were identified. The expression of hub genes in DMD versus normal muscle tissue was calculated in GSE6011.

Results:
12 co-expressed gene modules were identified, among which black module was significantly related to DMD. The characteristic genes in the module were enriched in the regulation of immune effector processes, immune response mediated by immunoglobulin, immune response mediated by B cells, etc. SERPING1, F13A1, C1S, C1R, and HLA-DPA1 were considered as hub genes in protein–protein interaction network. Analysis of GSE6011 shows that expression of SERPING1, F13A1, C1S, C1R, and HLA-DPA1 in tissues of DMD patients were higher than normal.

Conclusion:
SERPING1, F13A1, C1S, C1R, and HLA-DPA1 may participate in the development of DMD by regulating innate immunity and inflammation, and they are expected to be a potential biomarker and novel therapeutic targets for DMD.
Differentiation between IgG4-related Mikulicz disease and Sjögren’s syndrome: A review case report and literature review
Authors: Otani Yurie , Shimura Tomotaka , Nogaki Taketoshi , Ikenoya Yoichi , Oyake Koichiro , Imaizumi Naomi , Inoue Yukiko , Uruma Shuhei , Kamimura Sawa , Kawamura Yojiro , Kobayashi Sei 
Published: December 2022

Rationale:
IgG4-related diseases cause lesions in various organs throughout the body. In otorhinolaryngology, IgG4-related Mikulicz’s disease is suspected and diagnosed based on the presence of lesions of the head and neck, salivary and lacrimal gland enlargement, and bilateral sinus opacity concentrated on the maxillary sinuses. However, in some cases, it is necessary to consider about differentiation between IgG4-related Mikulicz’s disease and Sjögren syndrome.

Patient concerns and diagnosis:
A 75-years-old male patient visited our hospital with bilateral otitis media with effusion, which was resistant to conservative treatment. Other symptoms at presentation included enlarged bilateral submandibular and sublingual glands marked oral dryness, severe decrease in saliva secretion (1 mL/10 minutes), and dry eyes. We conducted a Schirmer’s and fluorescent dye tests, both of which were positive. High serum IgG4 levels were observed, and although the Sjögren syndrome (SS)-A/SS-B antibodies were negative, marked hypolacrimation and tear secretion were observed. Therefore, a detailed examination considering both IgG4-related Mikulicz’s disease and SS was conducted. Salivary gland scintigraphy performed prior to the salivary gland biopsy revealed a marked decrease in uptake, which satisfied the diagnostic criteria for SS; however, it was difficult to diagnose IgG4-related disease based on the diagnostic definition.

Intervensions:
Although a definitive diagnosis of SS was made, the persistent otitis media with effusion that was resistant to conservative treatment and bilateral mixed hearing loss were confirmed. As mixed hearing loss is considered an otological symptom of IgG4-related disease, oral steroid treatment was administered.

Outcome:
Thereafter, marked recovery of hearing and reduced swelling and induration of the bilateral parotid and submandibular glands were observed. Clinically, IgG4-related Mikulicz’s disease was strongly suspected, but a definite diagnosis of SS was made.

lessons:
In the absence of an IgG4-related Mikulicz’s disease diagnosis, careful differentiation between IgG4-related Mikulicz’s disease and 2 diseases and their diagnostic criteria was essential.
Outpatient Prosthetic Based Reconstruction During COVID-19 Pandemic Possible in Selected Patients Without Increased Complications
Authors: Manstein Samuel M , Laikhter Elizabeth , Boustany Ashley N , Shiah Eric , Comer Carly D , Bustos Valeria P , Singhal Dhruv , Fukudome Eugene Y , Cauley Ryan P , Morris Donald J , Lee Bernard T , Lin Samuel J 
Published: December 2022

Background:
Following the reopening of elective surgery, our division transitioned from inpatient admission to same-day discharge for immediate prosthetic breast reconstruction in an effort to decrease the hospital’s clinical burden and minimize potential COVID-19 exposure. This study aims to compare complication rates following this acute transition for patients who had inpatient and outpatient mastectomy with immediate alloplastic reconstruction.

Methods:
A retrospective chart review was performed on patients who underwent mastectomy with immediate prosthetic reconstruction. The outcome of interest was 30-day morbidity. Descriptive statistics were compared for patients with outpatient and inpatient surgeries. Odds ratios were calculated to determine whether any pre-operative factors increased odds of 30-day complications.

Results:
A total of 115 patients were included in this study. Twenty-six patients had outpatient surgery and 89 stayed inpatient postoperatively. Same-day discharge did not significantly impact the odds of having one or more 30-day complications (OR: 0.275, 95% CI: 0.047-1.618, p = 0.153). Patients with complications had significantly longer median operating times (5.0, IQR 4.0 – 6.0 vs. 4.0, IQR 3.0 – 5.0, p = 0.05), and there was a statistically significant association between length of surgery and odds of complication (OR: 1.596, 95% CI: 1.039-2.451, p = 0.033). Age was independently associated with increased risk of 30-day complication (OR: 1.062, 95% CI: 1.010-1.117, p = 0.020).

Conclusions:
Our findings support a continuation of same-day discharge strategy which could decrease costs for patients and hospitals without increasing complications.
Kidney Transplant and Dialysis Patients Remain at Increased Risk for Succumbing to COVID-19
Authors: Weiss Anne , Hendrickx Rodinde , Stensgaard Eva , Jellingsø Mads , Sommer Morten O.A. 
Published: December 2022

Background.Immunocompromised patients have been at an increased risk of succumbing to coronavirus disease 2019 (COVID-19) since the beginning of the pandemic.Methods.Here, we analyzed mortality and case fatality data from dialysis and kidney transplant patients, and compared each with an age-matched subgroup of the general population.Results.We found that both patients on dialysis and kidney transplant patients remain at increased risk of succumbing to COVID-19 despite all available countermeasures.Conclusions.The analyses underline the need for additional protection for this vulnerable population.
Cultivation of plant-growth promoters in vinasse: contributions for a circular and green economy
Authors: Torres Mariela Analía , Valdez Alejandra Leonor , Angelicola María Virginia , Raimondo Enzo Emanuel , Pajot Hipólito Fernando , Nieto-Peñalver Carlos Gabriel 
Published: December 2022

AbstractVinasse is a by-product with a key role in the circular economy. In this work, we analyze sugarcane vinasse as culture medium for obtaining single and mixed inoculants.Trichoderma harzianumwas cultured in single and sequential co-culture withPseudomonas capeferrumorRhizobiumsp. Fungal biomass was higher in vinasse than in a laboratory medium. Residual vinasses presented almost neutral pH and lower conductivities and toxicity than raw vinasse. Fertigation with residual vinasses improves characteristics of soil evidenced in the total N, cation exchange capacity, urease and acid phosphatase, and the microbial metabolic diversity, in comparison to raw vinasse. The evaluation of the treatment indicates that vinasse is suitable for the production of inoculants containingT. harzianumand that the co-culture withP. capeferrumimproves the characteristics of the residual vinasse in comparison toRhizobiumsp. Obtaining this valuable biomass in vinasse is relevant for the circular and green economy.
Smog risk perception, corporate social responsibility, and green innovation: evidence from China
Authors: Liu Zonghua , Guo Yulang , Zhang Ming , Mao Tianping 
Published: December 2022

Purpose
The purpose of this study is to investigate the main effect of top executive smog risk perception on green innovation and to examine the mediating role of corporate social responsibility (CSR) in the positive relationship between smog risk perception and green innovation along with the moderating role of smog knowledge.

Design/methodology/approach
A theoretical framework is developed based on the upper echelons theory to argue that top executive smog risk perception can be closely related to green innovation. Hierarchical analysis is conducted using a sample of eight firms in China.

Findings
Hypothesis testing indicates that physical health risk perception and mental health risk perception positively affect green innovation, and that these effects are positively mediated by CSR. In addition, smog knowledge moderates the relationship between physical health risk perception and green innovation.

Research limitations/implications
The findings extend current studies on green innovation by highlighting the role of top executives’ perceptions beyond studying top executives’ attributes. The findings suggest that top executives should actively respond to smog pollution and fulfill CSR.

Originality/value
Previous studies have suggested that top executives’ demographic characteristics are the determining factors of green innovation. This empirical paper fills a gap in the literature by exploring the impact of top executive smog risk perception on green innovation within the framework of the upper echelons theory.
English version of Japanese guidance for use of biologics for psoriasis (the 2022 version)
Authors: Saeki Hidehisa , Mabuchi Tomotaka , Asahina Akihiko , Abe Masatoshi , Igarashi Atsuyuki , Imafuku Shinichi , Okubo Yukari , Komine Mayumi , Sano Shigetoshi , Torii Hideshi , Morita Akimichi , Yotsuyanagi Hiroshi , Watanabe Akira , Ohtsuki Mamitaro ,   Committee for reviewing the safety of molecularly targeted drugs for psoriasis, Japanese Dermatological Association
Published: December 2022

AbstractThis is the English version of Japanese guidance for use of biologics for psoriasis (the 2022 version). As the first biologics for psoriasis in Japan, infliximab and adalimumab, anti‐tumor necrosis factor‐α antibodies, became available in the field of dermatology in 2010, followed by ustekinumab, an anti‐interleukin (IL)‐12/IL‐23p40 antibody, which was launched in Japan in 2011. Moreover, after 2015, three IL‐17 inhibitors, the IL‐17A antibody preparations secukinumab and ixekizumab, and an anti‐IL‐17 receptor antibody preparation brodalumab were marketed. Furthermore, after 2018, the anti‐IL23p19 antibody preparations guselkumab and risankizumab, the TNF inhibitor certolizumab pegol, the IL‐23 inhibitor tildrakizumab, and the anti‐IL‐17A/F antibody bimekizumab were marketed. It is important for physicians to select appropriate biologic therapy for each psoriatic patient after due consideration of disease factors, treatment factors, and patient background factors, sharing such information with patients. The followings can be listed as points to be considered for the selection of biologics: drug effects (e.g., strength of effectiveness, time to onset of effectiveness, effectiveness against arthritis, primary failure, secondary failure), safety (e.g., infections, administration‐related reactions, and relationships with other comorbidities), convenience for patients (e.g., hospital visit intervals, self‐injection, maintenance therapy at clinics, feasibility of drug discontinuation/re‐administration), and payment (medical costs) borne by patients. This guidance has been prepared with the aim of allowing dermatologists experienced in the treatment of psoriasis to use biologics appropriately according to the circumstances of individual patients after consideration of the above‐mentioned factors.
Umbilic points of slowness surface in elastic orthorhombic media
Authors: Xu Shibo , Stovas Alexey , Huang Xingguo 
Published: December 2022

AbstractFor 3D seismic data processing, azimuth plays an important role, especially in complex subsurface regions. In such regions, elliptical or anelliptical orthorhombic models are commonly used to describe wave propagation. In these models, the behaviour of the slowness surface needs more detailed analysis. Umbilic points defined by the equal principal curvatures exist in a complex 3D model. In the vicinity of the umbilic points, the traveltime surface has the shifted hyperbola form that needs to be considered in processing operations like velocity analysis. Fractured media characterized by the orthorhombic model are more likely to have umbilic points, and it is important to address their positions. If exists, umbilic points can provide additional constraints in inverting for model parameters. Through a defined condition, we examine the position of the umbilic point and derive their explicit formulas. We analyse umbilic points for elliptical and anelliptical orthorhombic models in the numerical example. For the elliptical orthorhombic model, the formulas for the umbilic point position on different symmetry planes are derived and corresponding conditions are also identified. Further, we numerically examine umbilic point positions for anelliptical orthorhombic models and observe that the umbilic points are located out of two vertical symmetry planes. Moreover, caused by interference from two neighbouring umbilic points, a more significant deviation in traveltime is found in the anelliptical orthorhombic model.
Elevated O3 concentrations alter the compartment‐specific microbial communities inhabiting rust‐infected poplars
Authors: Tao Siqi , Yin Haiyue , Fang Yue , Zhang Yunxia , Zhang Naili , Qu Laiye 
Published: December 2022

AbstractElevated ozone (O3) can affect the susceptivity of plants to rust pathogens. However, the collective role of microbiomes involved in such interaction remains largely elusive. We exposed two cultivated poplar clones exhibiting differential O3 sensitivities, to non‐filtered ambient air (NF), NF + 40 ppb or NF + 60 ppb O3‐enriched air in field open‐top chambers and then inoculated Melampsora larici‐populina urediniospores to study their response to rust infection and to investigate how microbiomes inhabiting four compartments (phyllosphere, rhizosphere, root endosphere, bulk soil) are involved in this response. We found that hosts with higher O3 sensitivity had significantly lower rust severity than hosts with lower sensitivity. Furthermore, the effect of increased O3 on the diversity and composition of microbial communities was highly dependent on poplar compartments, with the microbial network complexity patterns being completely opposite between the two clones. Notably, microbial source analysis estimated that phyllosphere fungal communities predominately derived from root endosphere and vice versa, suggesting a potential transmission mechanism between plant above‐ and below‐ground systems. These promising results suggest that further investigations are needed to better understand the interactions of abiotic and biotic stresses on plant performance and the role of the microbiome in driving these changes.