bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosis spectrum features, neurocognition and functioning in a longitudinal study of youth with 22q11.2 deletion syndrome
Authors: Gur Raquel E. , McDonald-McGinn Donna M. , Moore Tyler M. , Gallagher R. Sean , McClellan Emily , White Lauren , Ruparel Kosha , Hillman Noah , Crowley T. Blaine , McGinn Daniel E. , Zackai Elaine , Emanuel Beverly S. , Calkins Monica E. , Roalf David R. , Gur Ruben C. 
Published: March 2023

AbstractBackgroundNeuropsychiatric disorders are common in 22q11.2 Deletion Syndrome (22q11DS) with about 25% of affected individuals developing schizophrenia spectrum disorders by young adulthood. Longitudinal evaluation of psychosis spectrum features and neurocognition can establish developmental trajectories and impact on functional outcome.Methods157 youth with 22q11DS were assessed longitudinally for psychopathology focusing on psychosis spectrum symptoms, neurocognitive performance and global functioning. We contrasted the pattern of positive and negative psychosis spectrum symptoms and neurocognitive performance differentiating those with more prominent Psychosis Spectrum symptoms (PS+) to those without prominent psychosis symptoms (PS−).ResultsWe identified differences in the trajectories of psychosis symptoms and neurocognitive performance between the groups. The PS+ group showed age associated increase in symptom severity, especially negative symptoms and general nonspecific symptoms. Correspondingly, their level of functioning was worse and deteriorated more steeply than the PS− group. Neurocognitive performance was generally comparable in PS+ and PS− groups and demonstrated a similar age-related trajectory. However, worsening executive functioning distinguished the PS+ group from PS− counterparts. Notably, of the three executive function measures examined, only working memory showed a significant difference between the groups in rate of change. Finally, structural equation modeling showed that neurocognitive decline drove the clinical change.ConclusionsYouth with 22q11DS and more prominent psychosis features show worsening of symptoms and functional decline driven by neurocognitive decline, most related to executive functions and specifically working memory. The results underscore the importance of working memory in the developmental progression of psychosis.
‘God corresponds to Godself’: John Webster's doctrine of God ‘after’ Karl Barth
Authors: Rempel Brent 
Published: March 2023

AbstractThe nature and extent of Karl Barth's significance in John Webster's theological formation is widely recognised but remains to be explored in detail. Addressing this lacuna, this essay considers how Barth's doctrine of the triune God animates Webster's teaching on the same. In approaching the topic, I show how Webster carries forward Barth's deep sense of God's aseity in relation to the world and follows Barth in his commitment to the singularity of God's triune being. God's particularity and aseity converge in ‘God's self-correspondence’ (namely, that God ‘in Godself’ corresponds to God ‘for us’), which represents the core of Barth's influence on Webster's theology proper. The final section responds to Katherine Sonderegger's recent criticism of Webster's ‘relationalism’, which counts God's relation to creatures as an integral aspect of God's eternal life. I reframe the issue in terms of Webster's late-career retractions of the language of inclusion and divine self-determination, arguing that the difficulties that Sonderegger identifies in earlier writings are overcome in the final decade of Webster's corpus.
The effect of memory instructions on within- and between-language false memory
Authors: Beato Maria Soledad , Albuquerque Pedro B. , Cadavid Sara , Suarez Mar 
Published: March 2023

AbstractWe examined the effect of memory instructions on false memory using the Deese/Roediger–McDermott paradigm in second-language learners. Participants studied lists of words in L1 and L2 (e.g., note, sound, piano…) associatively related to a non-presented critical lure (e.g., MUSIC). In a later recognition test, critical lures appeared in the same or the other language of their lists (i.e., within- and between-language conditions). In Experiment 1, participants should only endorse an item when study and test languages matched (i.e., restrictive instructions); that is, they should retrieve language information. In Experiment 2, participants should endorse studied items regardless of the language (i.e., inclusive instructions). With restrictive instructions, false recognition was higher in within- than between-language conditions, whereas with inclusive instructions, this result was replicated only when words were studied in L1, but not L2. Results suggested that second-language learners show false memory in their L2 and that the effect of language shift on false recognition depended on the study language.
Partnership among peasants: rural England, 1270–1520
Authors: Dyer Christopher 
Published: March 2023

AbstractHistorians of medieval society tend to emphasise the roles of either individual peasants or the village community. They also debate the importance of the market in the peasant economy. Here the focus is on partnership, defined as two or more people pursuing common objectives in a mutual co-operative relationship. Peasants sometimes held land jointly, and new land might be cleared by two or more people. Pairs of peasants regularly took on paid work. It is argued that a likely explanation for occasional flurries of litigation was a breakdown of partnerships. The multiple legal disputes suggest the range of collaborative activities undertaken by peasants, from domestic bread making to the management of pastures. Partnerships may have contributed to the resilience of peasant holdings, especially in the period 1370–1420. Local courts and communities responded with peace-making measures if former partners lapsed into extreme hostility.
Coroners’ inquest juries in sixteenth-century England
Authors: Gunn Steven , Gromelski Tomasz 
Published: March 2023

AbstractJuries enabled the participation in local governance of those outside national and regional elites in early modern England. Yet their social range is disputed. We investigate coroners’ inquest juries in a range of communities and compare a sample of 148 juries in eleven counties, featuring 2024 jurors, with tax and muster records. These show that while the rural and urban middling sorts were disproportionately represented, the rich and poor were by no means excluded. As militarily able household heads, many jurors matched the wider demands of ‘respectable masculinity’, and this may be reflected in some of the verdicts they reached.
Cultural heritage and the International Court of Justice: Application of the International Convention on the Elimination of All Forms of Racial Discrimination (Armenia v. Azerbaijan), Provisional Measures, Order of 7 December 2021
Authors: Kirchmair Lando 
Published: March 2023

AbstractThis case note discusses the role of the International Court of Justice (ICJ) in the protection of cultural heritage. Of particular relevance in this vein is the cultural heritage dimension of the International Convention on the Elimination of All Forms of Racial Discrimination and its interpretation by the ICJ in its provisional measures order of 7 December 2021 in the proceedings on the Application of the International Convention on the Elimination of all Forms of Racial Discrimination (Armenia v. Azerbaijan). In this order, the ICJ indicated provisional measures to protect the cultural heritage of minorities and their right to equal participation in cultural activities. Looking ahead, the case note briefly elaborates on the potential implications of this order and the proceedings for the broader debate on the human right to cultural heritage.
UNESCO, world heritage and human rights
Authors: Vrdoljak Ana Filipa 
Published: March 2023

AbstractThis article examines the relationship between the World Heritage Convention and international human rights law. The first part of the article draws on key phrases in Article 1 of the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) Constitution, which defines its purpose to elaborate on the role of human rights to UNESCO’s mandate and how developments in international human rights law over the last 75 years have been translated into the organization’s policies and programs and the implementation of the World Heritage Convention. The second part details how human rights violations related to World Heritage properties expose significant shortcomings in UNESCO’s fulfillment of its mandate and states’ compliance with international human rights norms. The third part outlines the international responsibility of various actors in respect of serious violations of human rights related to World Heritage properties. The final part identifies possible areas of reform in the operation of the World Heritage Convention that may facilitate its alignment with international human rights law and UNESCO’s adherence to its mandate.
Hospital Disasters Preparedness for Mass-Casualty Incidents at Emergency Units in Northwest of Ethiopia: A Cross-Sectional Study
Authors: Getu Samuel Befekadu , Walle Tsegaw Fisseha , Arcos González Pedro , Castro Delgado Rafael 
Published: March 2023

AbstractBackground:Ethiopian policy and strategy aim to make health care systems capable of dealing with emergencies. However, Ethiopian health care still lacks a comprehensive “all-hazard” approach and a disaster preparedness program. Thus, this study aimed to assess the level of disaster preparedness in selected public hospitals for mass-casualty incidents (MCIs) in Amhara Regional State, Northwest Ethiopia.Methods:A descriptive cross-sectional study was conducted at general and comprehensive specialized hospitals (CSHs) in Amhara Regional State, Ethiopia using a World Health Organization (WHO) hospital emergency response checklist that included a domain on mass-casualty management (MCM) adapted from a literature review.Results:Seventeen (17) hospitals were evaluated (response rate: 81%). Five (29.4%) were teaching hospitals (tertiary health care) and 12 (70.5%) were non-teaching (secondary health care) hospitals. With an average mean of 97.3 (SD = 33.68; range 31-160), most hospitals under WHO required an Acceptable level of preparedness. Two were at an Unacceptable (0-67) level of preparedness, 12 (70.5%) hospitals were at an Insufficient (68-134) state, while the other three had an Acceptable (135-192) level of preparedness.Conclusion:The preparedness level of hospitals is Insufficient for potential MCIs in this region and needs prior attention in implementing existing strategic guidelines to develop and activate hospital disaster plans if and when needed.
How do empirical estimators of popular risk measures impact pro-cyclicality?
Authors: Bräutigam Marcel , Kratz Marie 
Published: March 2023

AbstractRisk measurements are clearly central to risk management, in particular for banks, (re)insurance companies, and investment funds. The question of the appropriateness of risk measures for evaluating the risk of financial institutions has been heavily debated, especially after the financial crisis of 2008/2009. Another concern for financial institutions is the pro-cyclicality of risk measurements. In this paper, we extend existing work on the pro-cyclicality of the Value-at-Risk to its main competitors, Expected Shortfall, and Expectile: We compare the pro-cyclicality of historical quantile-based risk estimation, taking into account the market state. To characterise the latter, we propose various estimators of the realised volatility. Considering the family of augmented GARCH(p, q) processes (containing well-known GARCH models and iid models, as special cases), we prove that the strength of pro-cyclicality depends on the three factors: the choice of risk measure and its estimators, the realised volatility estimator and the model considered, but, no matter the choices, the pro-cyclicality is always present. We complement this theoretical analysis by performing simulation studies in the iid case and developing a case study on real data.
Toward electoral (ir)relevance of moral traditionalism? Religious decline and voting in Western Europe (1981–2017)
Authors: Pless Anna , Tromp Paul , Houtman Dick 
Published: March 2023

AbstractThis article tests two contrasting hypotheses about changes in the electoral relevance of moral traditionalism–progressiveness, which pertains to attitudes toward matters of procreation, sexuality, and family and gender roles. While the “cultural turn” literature expects the electoral relevance of moral traditionalism to increase over time alongside that of all other cultural issues, studies inspired by secularization theory rather predict a decrease in its relevance—due to religious decline. Analyzing the data from the European Values Study (1981–2017) for 20 West European countries, we find empirical evidence for a decrease and no indication of an increase in the electoral relevance of moral traditionalism. Religious decline weakened the effect of moral traditionalism on religious and conservative voting over time due to the most traditionalist voters shifting away from these parties. Our findings, therefore, highlight the need to differentiate between different types of cultural motives behind voting choice in Western Europe.
Temperature and Climatic Seasonality Affecting C3 Versus C4 Plants Since the Last Deglacial on the Northeastern Tibetan Plateau
Authors: Ma Xueyun , Wei Zhifu , Wang Yongli , Wang Gen , Zhang Ting , Ma He , He Wei , Yu Xiaoli , Zhang Pengyuan 
Published: March 2023

AbstractThe climate reconstruction of the Tibetan Plateau, which was called the Third Pole Environment, has been a research hotspot in recent years. However, there are few studies on C3 and C4 plants evolution and it is an area of active debate on whether there are C4 plants existing on the Tibetan Plateau. In this study, the paleoclimate of the Hurleg Lake on the northeastern Tibetan Plateau is reconstructed based on n‐alkane‐induced indicators, while the C4 plant evolution history is established by compound‐specific isotope of long‐chain n‐alkanes since 14.1 cal kyr BP. The response of C4 plant evolution history to climate change on the northeastern margin of the Tibetan Plateau demonstrated that C3 and C4 plants were sensitive to local and global climate change. Solar radiation in summer, insolation‐affected East Asian monsoon, and seasonal climate (including seasonal variation of the solar radiation, temperature, and precipitation) had significant effects on the long‐term growth of C4. On the other hand, factors such as temperature, precipitation, and other potential factors affected the detailed variation of C4 plants in a relatively short‐term. Our finding maintained the existence of C4 plants in the high‐altitude region and indicated that the abundance of C4 plants might increase significantly and the ecological pattern of vegetation on the Tibetan Plateau will change distinctly in the coming warmer climate conditions.
A Lagrangian Study of Tidal Advection of Mesospheric Water Vapor
Authors: Koushik N. , Oberheide J. , Pedatella N. M. 
Published: March 2023

AbstractPrevious studies have demonstrated that the diurnal variability of mesospheric water vapor involves a non‐linear interplay between dynamics, photochemistry, and catalytic processes. The inherent difficulty in measurement of winds and water vapor in this region makes the study of mesospheric water vapor complex. Here we study the sources of diurnal variability of mesospheric water vapor with the help of the specified dynamics configuration of the Whole Atmosphere Community Climate Model (WACCM) with thermosphere‐ionosphere eXtension (SD‐WACCM‐X) for typical equinox conditions during the solar minimum year 2009. Special emphasis is given to the advective transport by the migrating diurnal tide and its impact on the mean water vapor in the mesosphere. To isolate the contribution from advective and non‐advective processes, a Lagrangian parcel trajectory model is employed. Using this model, we incorporated the effect of both vertical and horizontal tidal advection on the diurnal variability of mesospheric water vapor. Our results indicate that the vertical tidal advection dominates the transport of water vapor in the upper mesosphere and that there is a significant contribution from horizontal tidal advection below 70 km. Among non‐advective processes, chemical loss of water vapor has the largest contribution. The Lagrangian parcel trajectory approach is further extended using the recently released version 2.07 of water vapor observations from the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) instrument and dynamical tides from the empirical Climatological Tidal Model for the Thermosphere (CTMT). Differences in SD‐WACCM‐X and CTMT + SABER results are discussed in light of the veracity of SABER water vapor measurements.
Plant latent defense response against compatibility
Authors: Zhang Huiming 
Published: March 2023

Abstract
Managing the association with microbes is crucial for plants. Evidence is emerging for the plant latent defense response, which is conditionally elicited by certain microbial nonpathogenic factors and thereby guards against potential risks from beneficial or commensal microbes. Latent defense response is an exciting new research area with a number of key issues immediately awaiting exploration. A detailed understanding of latent defense response will underpin the applications of beneficial microbes.
Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice
Authors: Yu Jia-yu , Cao Nancy , Rau Christoph D. , Lee Ro-Po , Yang Jieping , Flach Rachel J. Roth , Petersen Lauren , Zhu Cansheng , Pak Yea-Lyn , Miller Russell A. , Liu Yunxia , Wang Yibin , Li Zhaoping , Sun Haipeng , Gao Chen 
Published: March 2023

AbstractParallel to major changes in fatty acid and glucose metabolism, defect in branched-chain amino acid (BCAA) catabolism has also been recognized as a metabolic hallmark and potential therapeutic target for heart failure. However, BCAA catabolic enzymes are ubiquitously expressed in all cell types and a systemic BCAA catabolic defect is also manifested in metabolic disorder associated with obesity and diabetes. Therefore, it remains to be determined the cell-autonomous impact of BCAA catabolic defect in cardiomyocytes in intact hearts independent from its potential global effects. In this study, we developed two mouse models. One is cardiomyocyte and temporal-specific inactivation of the E1α subunit (BCKDHA-cKO) of the branched-chain α-ketoacid dehydrogenase (BCKDH) complex, which blocks BCAA catabolism. Another model is cardiomyocyte specific inactivation of the BCKDH kinase (BCKDK-cKO), which promotes BCAA catabolism by constitutively activating BCKDH activity in adult cardiomyocytes. Functional and molecular characterizations showed E1α inactivation in cardiomyocytes was sufficient to induce loss of cardiac function, systolic chamber dilation and pathological transcriptome reprogramming. On the other hand, inactivation of BCKDK in intact heart does not have an impact on baseline cardiac function or cardiac dysfunction under pressure overload. Our results for the first time established the cardiomyocyte cell autonomous role of BCAA catabolism in cardiac physiology. These mouse lines will serve as valuable model systems to investigate the underlying mechanisms of BCAA catabolic defect induced heart failure and to provide potential insights for BCAA targeted therapy.
Oculo-dento-digital dysplasia: a systematic analysis of published dental literature
Authors: Hindu Karshma Devi , Umer Fahad 
Published: March 2023

AbstractIntroductionOculo-dento-digital dysplasia (ODDD, OMIM# 164200) is a rare genetic disorder caused by mutation in Gap junction alpha gene that encodes connexin 43 (Cx43) protein. In this paper, the case of a 16-year-old boy is reported who presented with the complaint of toothache. Examination revealed unusual facial features, i.e., long narrow nose, hypertelorism, prominent epicanthal folds along with syndactyly and camptodactyly. We have also compiled available dental literature on ODDD that will help clinicians in early diagnosis and management of this condition.Materials and methodsA literature search was performed in PubMed NLM, EBSCO Dentistry & Oral Sciences Source, and EBSCO CINAHL Plus.ResultsA total of 309 articles were identified in the literature search. Only 17 articles were included based on the predetermined inclusion and exclusion criteria in the review synthesis. The included articles were case reports (n = 15), a case report and review (n = 1), and an original article (n = 1). Enamel hypoplasia, hypomineralization, microdontia, pulp stones, curved roots, and taurodontism were common dental findings in ODDD.ConclusionsAfter establishing definitive diagnosis, a multidisciplinary team should work in cohesion to improve the quality of life of patients. Immediate treatment should be focused on the correction of current oral condition and symptomatic treatment. In the long term, attention should be diverted to prevent tooth wear and maintaining the occlusal vertical dimension to establish adequate function.
National contributions to climate change due to historical emissions of carbon dioxide, methane, and nitrous oxide since 1850
Authors: Jones Matthew W. , Peters Glen P. , Gasser Thomas , Andrew Robbie M. , Schwingshackl Clemens , Gütschow Johannes , Houghton Richard A. , Friedlingstein Pierre , Pongratz Julia , Le Quéré Corinne 
Published: March 2023

AbstractAnthropogenic emissions of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) have made significant contributions to global warming since the pre-industrial period and are therefore targeted in international climate policy. There is substantial interest in tracking and apportioning national contributions to climate change and informing equitable commitments to decarbonisation. Here, we introduce a new dataset of national contributions to global warming caused by historical emissions of carbon dioxide, methane, and nitrous oxide during the years 1851–2021, which are consistent with the latest findings of the IPCC. We calculate the global mean surface temperature response to historical emissions of the three gases, including recent refinements which account for the short atmospheric lifetime of CH4. We report national contributions to global warming resulting from emissions of each gas, including a disaggregation to fossil and land use sectors. This dataset will be updated annually as national emissions datasets are updated.