bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avaliação do conhecimento dos pais sobre a desobstrução de vias aéreas em crianças menores de cinco anos de idade
Authors: Rodrigues Dara Gonzalez , Silva Maria Eduarda Alves , Ribeiro Luana Sanches , Lozano Tatiani da Silva Palhota , Dias Ricardo Burato , Bento Vera Franco da Silva 
Published: July 2023

Objetivo: Compreender a percepção dos pais sobre a desobstrução de vias aéreas em crianças menores de cinco anos de idade. Método: Diante disso, o estudo de caráter descritivo-exploratório com uma abordagem quantitativa buscou investigar o conhecimento prévio dos pais acerca do assunto e demonstrar a importância de orientá-los sobre como agir nos casos da emergência. Foram abordados 21 participantes, através da Unidade Básica de Saúde Urbino Pasqual Bailão de Nova Luzitânia-SP e aplicado de forma online um questionário a respeito da desobstrução de vias aéreas. Resultados: Dados demonstram alto índice de óbito em menores de cinco anos de idade por obstrução de vias aéreas por aspiração de corpo estranho. Considerações Finais: O estudo revela que poucos pais receberam orientação sobre desengasgo pela equipe de saúde, porém, a maioria dos participantes relataram conhecer a manobra de Heimlich e nenhum deles obteve esse conhecimento através das instituições de saúde.
International Road Race of São Silvestre: why don't brazilians win anymore and what do we need to do?
Authors: Da Silva Ronaldo Aparecido 
Published: July 2023

Aim: To compare the Brazilian and foreign runners in the International Road Race of São Silvestre. Methods: Retrospective study that evaluated the results of 220 athletes of both genders that reached the top 10. The time of each race was converted in seconds to compare the performance. Results: After 11 editions of the International Road Race of São Silvestre only one Brazilian athlete won without any female victory. In the male 10 foreign athletes won (Kenya 5 x 5 Ethiopia) and all the females proved were won by foreign athletes (Kenya 9 x 2 Ethiopia). There was a difference when comparing the performance of foreign elite runners in the male (p<0.004) and female (p<0.001). Conclusion: Despite the large number of existing runners, the Brazilian elite does not develop the same level of performance to beat African athletes. To change this condition, it is necessary to change the strategy for preparing Brazilian athletes from the base of training athletes.
Eficácia clínica de novos estudos para o tratamento da Dermatite Atópica: uma revisão integrativa
Authors: De Campos Kaique Augusto Marques , Prado José Augusto Queiroz , Oliveira Bruno Henrique de Melo , Almeida João Pedro Arantes de Sousa , Duarte Ana Flávia Miranda de Carvalho , Silva Maria Emília Pereira , Carregosa Mateus Dias , Batista Paulo Henrique de Carvalho , Boaretto Bruna Luiza da Silva , De Carvalho Luana Iorio , De Souza Pedro Érico Alves 
Published: July 2023

A dermatite atópica (DA) é a doença de pele mais comum dentre as doenças inflamatórias crônicas da pele, acometendo de 10 a 20% das crianças e até 10% dos adultos em países desenvolvidos. O presente estudo de revisão buscou avaliar a eficácia clínica de novos estudos para o tratamento da dermatite atópica, documentados por meio de estudos clínicos e randomizados. Trata-se de uma pesquisa de revisão integrativa realizada por meio da base de dados PubMed, que levou em consideração os seguintes critérios de inclusão: ensaios clínicos e testes controlados e randomizados; artigos publicados no último ano; que possuíam texto completo disponível e que abordassem acerca da terapêutica da dermatite atópica (DA). Ficou constatado que o brepocitinibe tópico se mostrou bem tolerado nos pacientes que possuem DA de grau leve e moderado, da mesma forma que o upadacitinibe, o qual apresenta um perfil de risco-benefício favorável para o tratamento da DA moderada e grave em adolescentes. Além disso, o abrocitinibe também demonstrou resultados eficazes, com melhora da qualidade de vida e da coceira noturna em pacientes com DA. Verificou-se, ainda, que os anticorpos neutralizantes de IL-13 apresentam eficácia clínica comprovada em pacientes com DA, em especial quando associados aos costicosteroides tópicos. Essa associação com o traloquinumabe trouxe melhorias de sintomas, com redução de interferência no sono relacionado ao eczema, resultados semelhantes de eficácia quando os corticosteroides são associados ao lebrikizumabe.
Ціннісний потенціал компетентнісної освіти Нової української школи
Authors: Черній Алла , Гавлітіна Тетяна 
Published: July 2023

У статті окреслено ціннісний потенціал компетентністого змісту освіти Нової української школи, що поєднує навчання, виховання, розвиток особистості учня та сприяє створенню ефективного освітнього середовища, покликаного підвищувати рівень академічних досягнень учнів та розвивати навички міжособистісного діалогового спілкування, які зберігаються впродовж усього життя. Доведено, що позитивну атмосферу партнерської взаємодії, сповнену свободи, довіри та безпеки, формують саме батьки і вчителі як найголовніші носії цінностей, які переймають учні.
Обґрунтовано, що ціннісно зорієнтована освіта в Новій українській школі – це передусім виховання характеру особистості учня, намагання разом із класним колективом створити допоміжні структури для сприяння розвитку позитивних, етичних, просоціальних схильностей і компетентностей у дітей та учнівської молоді, зокрема щодо посилення академічної та ціннісної спрямованості досягнень, формування в умовах виховної системи закладу загальної середньої освіти спільних цінностей.
Закцентовано увагу на тому, що навчання, виховання, розвиток особистості учня на цінностях Нової української школи здійснюється завдяки ціннісним орієнтирам компетентнісної освіти; новим освітнім практикам і педагогічним стратегіям ефективної взаємодії однолітків; виявленню особистих переваг, прихованих талантів і реалізації ідей щодо допомоги іншим; зосередженню на побудові стосунків з оточуючими;, розширенню можливостей вихованців; критичним дискусіях про поведінку та ціннісні ставлення щодо взаємодії та їхні наслідки; позитивному спілкуванню з наставниками; баченню особистості дитини в центрі місії закладу; партнерській взаємодії з батьками тощо.
La relation aux traditions et aux modes de socialisation traditionnels des Églises évangéliques Born Again aux Philippines
Authors: Ianni Jérémy 
Published: July 2023

Bien que développant un discours critique à l’encontre de certaines traditions, les Églises Born Again aux Philippines sont populaires puisque de plus en plus de personnes les rejoignent. À partir d’une enquête de terrain et de données collectées dans le réseau du Conseil des Églises évangéliques des Philippines, l’auteur montre que, même si ces Églises tendent à remettre en cause certaines traditions, elles s’appuient cependant sur des modes traditionnels de socialisation pour se développer. Entre moi collectif – c’est la figure du kapwa – et unité, l’organisation du pouvoir charismatique religieux aux Philippines repose notamment sur des socialisations traditionnelles.
Psychologists’ experiences and perspectives of adults with long-Covid and neurodiversity, including intellectual disabilities
Authors: Rawlings Gregg H. , Beail Nigel 
Published: July 2023

While there is an increasing number of studies aimed at better understanding long-Covid, there is a lack of research involving people with intellectual disabilities (ID). We asked 12 psychologists working in long-Covid services, their views of the condition in adults with neurodiversity. While it was relatively common for psychologists to work with people with neurodiversity and long-Covid, eight had never worked with someone with ID in their service. Psychologists identified factors that may be predispose, precipitate, and perpetuate the condition in this group. Data reflects the importance of considering the intersection between ID and long-Covid. Guidelines recommend the adaptations of long-Covid treatments for people with ID; we provide examples of how this could be achieved.Easy to read summary■The symptoms that people can experience after recovering from the Covid-19 virus has been called long-Covid or post-Covid syndrome.■While we are learning more about long-Covid, there is little research that includes people with neurodiversity.■Psychologists in services for people with long-Covid do not see people with intellectual disability often.■Our findings can help guide research being conducted in this area, and clinicians who are likely to encounter someone with long-Covid and neurodiversity.
An audit of psychology risk screen completion across five time points and consideration of risk content
Authors: Hearn Michael 
Published: July 2023

This paper describes an audit of completion of psychology risk-screens by psychology staff across a 20-month period, taken at five time-points, in a single North London Borough. A dramatic improvement in completion rate was observed over this period. For the final audit period (May, 2022) the extent of co-occurrence of self-harm/self-injury (SIB) and aggression was assessed and a strong positive association was observed.Easy to read summaryIn our learning disabilities team we need to make sure the people we meet are safe. We ask people if they hurt themselves or other people. We need to keep a note of this so we can try to help. This is called a risk assessment. We had a look at our notes to see if we were good at doing risk assessments. To start with we noticed that we were not doing many. We tried harder. Every few months for nearly two years we checked. In the end we had got a lot better at doing risk assessments. We also found that if someone hurts themself it is more likely that they might try to hurt someone else, even if they do not do this on purpose.
NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ VIÊM SỤN VÀNH TAI CÓ TỤ DỊCH TẠI THÀNH PHỐ CẦN THƠ NĂM 2021-2023
Authors: Nguyễn Tri Minh Trí , Nguyễn Kỳ Duy Tâm , Dương Hữu Nghị 
Published: July 2023

Đặt vấn đề: Viêm sụn vành tai có tụ dịch là bệnh lý không thường gặp trong chuyên khoa Tai Mũi Họng, bệnh có thể được điều trị dễ dàng ở giai đoạn sớm nhưng cũng có thể diễn tiến đến hoại tử sụn gây biến dạng vành tai và ảnh hưởng đến thẩm mỹ của bệnh nhân. Mục tiêu nghiên cứu: Mô tả đặc điểm lâm sàng và đánh giá kết quả điều trị của viêm sụn vành tai có tụ dịch. Đối tượng và phương pháp nghiên cứu: 53 bệnh nhân được chẩn đoán và điều trị viêm sụn vành tai có tụ dịch. Sử dụng phương pháp mô tả, tiến cứu có can thiệp. Kết quả: Bệnh xảy ở nam cao hơn nữ. Các nguyên nhân gây bệnh thường gặp: bấm khuyên tai xuyên sụn (30,2%), chấn thương (26,4%) và không rõ nguyên nhân (32,1%). Tỷ lệ triệu chứng thực thể là: sưng, phồng vành tai (86,8%), nóng đỏ (42,7%), rò mủ (41,5%), biến dạng (34%), rò dịch (20,8%). Vị trí thường gặp nhất của viêm sụn vành tai có tụ dịch là 2/3 trên (32,1%), kế đến là 1/3 trên (28,3%). Kích thước thường gặp là 2-3 cm chiếm 43,4%. Kết luận: Tỷ lệ viêm sụn vành tai có tụ dịch có kết quả điều trị tốt khá cao, tuy nhiên khả năng di chứng sẹo xấu như tai súp lơ ảnh hưởng đến kết quả thẫm mỹ cuối cùng phụ thuộc vào lượng sụn bị tổn thương và được nạo vét.
Pengaruh Ukuran Butir Batupasir Terhadap Nilai Point Load Index Test Pada Formasi Balikpapan Dan Pulau Balang
Authors: Malik Abdul , Trides Tommy , Magdalena Henny , Oktaviani Revia , Juvensius Pontus Albertus 
Published: July 2023

Batupasir memiliki variasi ukuran butir yang sangat beragam mulai dari ukuran butir sangat halus sampai ukuran butir sangat kasar. Skala wentworth sebagai dasar penentu ukuran butir digunakan pada penelitian ini ukuran butir sangat halus hingga sangat kasar terdapat pada batuan yang telah di uji dimana ukuran butir tersebut menjadi faktor pembeda pada saat sampel di uji menggunakan alat uji point load index. Penelitan ini menggunakan metode kuantitatif dimulai dari data koordinat lokasi pengambilan sampel batuan, sifat fisik batuan, dan kemudian data sifat mekanik batuan yang merupakan data primer. Ada 8 lokasi pengambilan sampel pada penelitian ini yang terdiri dari 2 formasi yang berbeda yaitu formasi balikpapan dan formasi pulaubalang. Hasil pengujian point load index pada penelitian ini menunjukan bahwa ukuran butir mempunyai pengaruh terhadap nilai point load index ,semakin kecil ukuran butir maka nilai point load index besar, diikuti dengan bentuk sampel blok memiliki nilai point load index lebih tinggi dibandingkan bentuk sampel silinder dan irregular terlihat pada formasi balikpapan dengan bentuk irregular memiliki nilai sebesar 0,05 MPa untuk bentuk silinder memiliki nilai sebesar 0,10 MPa dan pada bentuk blok memiliki nilai tertinggi pada ukuran butir yang sama dengan nilai point load index sebesar 0,27 MPa begitu juga pada formasi pulau balang sampel bentuk blok memiliki nilai paling tinggi sebesar 0,67 MPa di ikuti dengan bentuk sampel silinder dengan nilai point load index sebesar 0,34 MPa dan untuk bentuk sampel irregullar memiliki nilai point load index sebesar 0,09 MPa
Biopolymer‐Polysiloxane Double Network Aerogels
Authors: Takeshita Satoru , Ono Takumi 
Published: July 2023

AbstractA new series of transparent aerogels of biopolymer‐polysiloxane double networks is reported. Biopolymer aerogels have attracted much attention from green and sustainable aspects but suffered from strong hydrophilicity and difficulty to make homogeneous structures in nanoscale; these drawbacks are overcome by compositing with a polysiloxane network. Alginate‐polymethylsilsesquioxane aerogel has high optical transparency, water repellency, comparable superinsulation property and improved bending flexibility compared to pure polymethylsilsesquioxane aerogel. The nanoscale homogeneity is realized by separating the crosslinking steps for two networks in a sequential protocol: condensation of siloxane bonds and metal‐crosslinking of biopolymer. The crosslinking order, biopolymer‐first or siloxane‐first, and universality/limitation of biopolymer‐crosslinker pairs are discussed to construct fundamental chemistry of double network systems for their further application potentials.
Retinal disease projection conditioning by biological traits
Authors: Hassan Muhammad , Zhang Hao , Fateh Ahmed Ameen , Ma Shuyue , Liang Wen , Shang Dingqi , Deng Jiaming , Zhang Ziheng , Lam Tsz Kwan , Xu Ming , Huang Qiming , Yu Dongmei , Zhang Canyang , You Zhou , Pang Wei , Yang Chengming , Qin Peiwu 
Published: July 2023

AbstractFundus image captures rear of an eye which has been studied for disease identification, classification, segmentation, generation, and biological traits association using handcrafted, conventional, and deep learning methods. In biological traits estimation, most of the studies have been carried out for the age prediction and gender classification with convincing results. The current study utilizes the cutting-edge deep learning (DL) algorithms to estimate biological traits in terms of age and gender together with associating traits to retinal visuals. For the trait’s association, we embed aging as the label information into the proposed DL model to learn knowledge about the effected regions with aging. Our proposed DL models named FAG-Net and FGC-Net, which correspondingly estimates biological traits (age and gender) and generates fundus images. FAG-Net can generate multiple variants of an input fundus image given a list of ages as conditions. In this study, we analyzed fundus images and their corresponding association in terms of aging and gender. Our proposed models outperform randomly selected state-of-the-art DL models.
A field work report on newly discovered and documented megalithic jar sites in the Lao People’s Democratic Republic
Authors: Skopal Nicholas , Bounxaythip Souliya , O’Reilly Dougald , Shewan Louise , Luangkhoth Thonglith , Van Den Bergh Julie 
Published: July 2023

AbstractXieng Khouang and neighboring provinces in Central Laos are home to a vast megalithic landscape featuring large stone jars, discs, and imported boulders located in elevated positions. Sites were first noted in the late nineteenth century, with systematic recording commencing in the 1930s. Continuing on from the 2019 field survey by the Plain of Jars Archaeological Research Project, this paper presents the results of a 2020 survey across Xieng Khouang Province, Lao People’s Democratic Republic (PDR) which led to the documentation of 27 previously unreported megalithic sites, growing the Lao PDR Government database from 102 to 127 known jar sites, with 124 geo-located. In addition, a preliminary analysis of the known jar sites to date is conducted regarding distribution and jar characteristics providing a basis for further investigation.
Biochar and zero-valent iron sand filtration simultaneously removes contaminants of emerging concern and Escherichia coli from wastewater effluent
Authors: Zhu Linyan , Chattopadhyay Suhana , Elijah Akanbi Oluwasegun , Lobo Steven , Panthi Suraj , Malayil Leena , Craddock Hillary A. , Allard Sarah M. , Sharma Manan , Kniel Kalmia E. , Mongodin Emmanuel F. , Chiu Pei C. , Sapkota Amir , Sapkota Amy R. 
Published: July 2023

AbstractAdvanced treated municipal wastewater is an important alternative water source for agricultural irrigation. However, the possible persistence of chemical and microbiological contaminants in these waters raise potential safety concerns with regard to reusing treated wastewater for food crop irrigation. Two low-cost and environmentally-friendly filter media, biochar (BC) and zero-valent iron (ZVI), have attracted great interest in terms of treating reused water. Here, we evaluated the efficacy of BC-, nanosilver-amended biochar- (Ag-BC) and ZVI-sand filters, in reducing contaminants of emerging concern (CECs), Escherichia coli (E. coli) and total bacterial diversity from wastewater effluent. Six experiments were conducted with control quartz sand and sand columns containing BC, Ag-BC, ZVI, BC with ZVI, or Ag-BC with ZVI. After filtration, Ag-BC, ZVI, BC with ZVI and Ag-BC with ZVI demonstrated more than 90% (> 1 log) removal of E. coli from wastewater samples, while BC, Ag-BC, BC with ZVI and Ag-BC with ZVI also demonstrated efficient removal of tested CECs. Lower bacterial diversity was also observed after filtration; however, differences were marginally significant. In addition, significantly (p < 0.05) higher bacterial diversity was observed in wastewater samples collected during warmer versus colder months. Leaching of silver ions occurred from Ag-BC columns; however, this was prevented through the addition of ZVI. In conclusion, our data suggest that the BC with ZVI and Ag-BC with ZVI sand filters, which demonstrated more than 99% removal of both CECs and E. coli without silver ion release, may be effective, low-cost options for decentralized treatment of reused wastewater.
Graphical Abstract
Dynamical downfolding for localized quantum states
Authors: Romanova Mariya , Weng Guorong , Apelian Arsineh , Vlček Vojtěch 
Published: July 2023

AbstractWe introduce an approach to treat localized correlated electronic states in the otherwise weakly correlated host medium. Here, the environment is dynamically downfolded on the correlated subspace. It is captured via renormalization of one and two quasiparticle interaction terms which are evaluated using many-body perturbation theory. We outline the strategy on how to take the dynamical effects into account by going beyond the static limit approximation. Further, we introduce an efficient stochastic implementation that enables treating the host environment with a large number of electrons at a minimal computational cost. For a small explicitly correlated subspace, the dynamical effects are critical. We demonstrate the methodology by reproducing optical excitations in the negatively charged NV center defect in diamond, that agree with experimental results.
Effect of angiotensin II on irradiation exacerbated decompression sickness
Authors: Fan Jie-Fu , Wang Yang-Kai , Liu Min , Liu Guang-Sheng , Min Tian-Jiao , Chen Rui-Yong , He Ying 
Published: July 2023

AbstractIn some complicated situations, decompression sickness (DCS) combined with other injuries, such as irradiation, will seriously endanger life safety. However, it is still unclear whether irradiation will increase the incidence of DCS. This study was designed to investigate the damage effects of irradiation on decompression injury and the underlying mechanism. Sprague–Dawley rats were exposed to irradiation followed by hyperbaric decompressing and the mortality and decompression symptoms were observed. Lung tissue and bronchoalveolar lavage fluid were collected to detect the lung lesion, inflammation response, activity of the angiotensin system, oxidative stress, and relative signal pathway by multiple methods, including Q-PCR, western blot, and ELISA. As a result, pre-exposure to radiation significantly exacerbated disease outcomes and lung lesions of DCS. Mechanically, the up-regulation of angiotensin-converting enzyme expression and angiotensin II levels was responsible for the exacerbated DCS and lung lesions caused by predisposing irradiation exposure. Oxidative stress and PI3K/AKT signal pathway activation in pulmonary tissue were enhanced after irradiation plus decompression treatment. In conclusion, our results suggested that irradiation could exacerbate lung injury and the outcomes of DCS by activating the angiotensin system, which included eliciting oxidative stress and activation of the PI3K/AKT signal pathway.
Targeting CD47-SIRPa axis shows potent preclinical anti-tumor activity as monotherapy and synergizes with PARP inhibition
Authors: Al-Sudani Hussein , Ni Ying , Jones Philip , Karakilic Huseyin , Cui Lei , Johnson Lisa D. S. , Rose Peter G. , Olawaiye Alexander , Edwards Robert P. , Uger Robert A. , Lin Gloria H. Y. , Mahdi Haider 
Published: July 2023

AbstractThe objective was to correlate CD47 gene expression with resistance to immune checkpoint inhibitors (ICI) in tumor tissue of gynecological cancer (GC). Further, we sought to assess the efficacy of targeting CD47 pathway alone and in combination in pre-clinical ovarian cancer (OC) models. We performed transcriptomic analyses in GC treated with ICI. Signaling pathway enrichment analysis was performed using Ingenuity Pathway Analysis. Immune cell abundance was estimated. CD47 expression was correlated with other pathways, objective response, and progression-free survival (PFS). Anti-tumor efficacy of anti-CD47 therapy alone and in combination was investigated both in-vitro and in-vivo using cell-line derived xenograft (CDX) and patient-derived xenograft (PDX) models. High CD47 expression associated with lower response to ICI and trended toward lower PFS in GC patients. Higher CD47 associated negatively with PDL1 and CTLA4 expression, as well as cytotoxic T-cells and dendritic cells but positively with TGF-β, BRD4 and CXCR4/CXCL12 expression. Anti-CD47 significantly enhanced macrophage-mediated phagocytosis of OC cells in-vitro and exhibited potent anti-tumor activity in-vivo in OC CDX and PDX models. In-vitro treatment with PARPi increased CD47 expression. Anti-CD47 led to significantly enhanced in-vitro phagocytosis, enhanced STING pathway and synergized in-vivo when combined with PARP inhibitors in BRCA-deficient OC models. This study provides insight on the potential role of CD47 in mediating immunotherapy resistance and its association with higher TGF-β, BRD4 and CXCR4/CXCL12 expression. Anti-CD47 showed potent anti-tumor activity and synergized with PARPi in OC models. These data support clinical development of anti-CD47 therapy with PARPi in OC.