bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS FAKTOR RISIKO DAN KONSEKUENSI BURNOUT PADA PERAWAT DI RUMAH SAKIT SWASTA DI JAKARTA
Authors: Mirza Muhammad Navis 
Published: August 2023

Tenaga kesehatan professional seperti perawat yang secara langsung berinteraksi dengan pasien dalam jangka waktu lama dan terus menerus dapat menimbulkan terjadinya gejala burnout. Ada beberapa hal yang dapat menyebabkan burnout pada pekerja terutama di area pekerjaan (Area of worklife) yang terdiri dari beban kerja, kontrol, reward, komunitas, keadilan, dan nilai. terdapat banyak penelitian tentang burnout dan konsekuensi yang timbul seperti job satisfaction, kurang berkomitmen untuk perusahaan, dengan demikian lebih mungkin untuk berhenti dari pekerjaan mereka. Namun sejauh ini fenomena burnout masih belum mendapat perhatian serius dari pihak manajemen, meskipun sudah banyak hasil penelitian yang memperlihatkan bahwa burnout menurunkan efektifitas organisasi. Oleh karena itu penulis berusaha untuk menganalisis faktor risiko dan konsekuensi burnout Pada perawat di rumah sakit swasta di jakarta. Metode penelitian kuantitatif dengan desain studi cross sectional untuk menganalisis 3 dimensi burnout serta hubungan dengan faktor predisposisi area of worklife serta efeknya terhadap kepuasan kerja, keinginan untuk keluar dan komitmen pekerja pada perusahaan. Usia, masa kerja dan jenis kelamin. berhubungan emotional exhaustion, jenis kelamin dan status pernikahan berhubungan terhadap cynicism dan lack of personal efficacy. area of worklife (workload, control, reward, community, fairness, value) yang memiliki hubungan dengan burnout (exhaustion, cynicism, lack of personal efficacy). Burnout yang berhubungan dengan konsekuensi dari burnout. Burnout memiliki hubungan/pengaruh mediasi antara faktor risiko burnout dan konsekuensi Burnout.
GAMBARAN TINGKAT PENGETAHUAN IBU TERHADAP PERILAKU PENCEGAHAN DIARE PADA BALITA DI WILAYAH KERJA PUSKESMAS KALUMPANG
Authors: Aja Nursia , Patilaya Hairudin La , Djafar Monissa A Hi , Merdekawati Diah , Surasno Surasno 
Published: August 2023

Diare adalah keadadan frekuensi buang air besar lebih dari 3 kali bagi anak, konsistensi feses encer, dapat berwarna hijau atau dapat pula bercampur lendir dan darah atau lendir saja . Penyebab utama kematian akibat diare adalah tatalaksana yang tidak tepat baik di rumah maupun di sarana kesehatan. Salah satu upaya mencegah kasus diare adalah dengan berperilaku Hidup Bersih dan Sehat (PHBS) terhadap pada balita. Penelitian ini bertujuan untuk melihat gambaran tingkat pengetahuan tentang pencegahan diare pada balita, perilaku dan upaya pencegahan ibu tentang diare dengan perilaku pencegahan terhadap diare pada balita. Penelitian ini merupakan penelitian observasional dengan teknik potong lintang (cross-sectional study) untuk melihat gambaran diare dengan perilaku pencegahan diare pada balita. Populasi dalam penelitian ini adalah seluruh penderita diare yang tercatat dalam buku register penderita di Puskesmas Kalumpang. Hasil analisis univariat menggambarkan distribusi frekuensi berdasarkan karakteristik demografi meliputi usia balita < 12 bulan sebesar 36%, jenis kelamin laki-laki lebih besar 54.5%. selain itu distribusi frekuensi berupa presentase variabel tingkat pendidikan rendah lebih besar 54.3%, perilaku baik sebesar 50.1% sedangkan variabel upaya pencegahan baik sebesar 57.2%. Disarankan kepada pihak Puskesmas agar memperikan sosialisasi atau pemahaman tentang pengetahuan dan praktek cuci tangan yang benar untuk mencegah Kejadian Diare anggota keluarga. Perlu adanya kerjasama antara pihak Puskesmas dengan anggota keluarga terhadap mencega terjadinya diare pada balita.
Modeling of spatial spread of COVID-19 pandemic waves in Russia using a kinetic-advection model
Authors: Aristov V. V. , Stroganov A. V. , Yastrebov A. D. 
Published: August 2023

Objectives. COVID-19 has a number of specific characteristics that distinguish it from past pandemics. In addition to the high infection rate, the high spread rate is due to the increased mobility of contemporary populations. The aim of the present work is to construct a mathematical model for the spread of the pandemic and identify patterns under the assumption that Moscow comprises the main source of viral infection in Russia. For this purpose, a twoparameter kinetic model describing the spatial spread of the epidemic is developed. The parameters are determined using theoretical constructions alongside statistical vehicle movement and population density data from various countries, additionally taking into account the development of the first wave on the examples of Russia, Italy and Chile with verification of values obtained from subsequent epidemic waves. This paper studies the development of epidemic events in Russia, starting from the third and including the most recent fifth and sixth waves. Our twoparameter model is based on a kinetic equation. The investigated possibility of predicting the spatial spread of the virus according to the time lag of reaching the peak of infections in Russia as a whole as compared to Moscow is connected with geographical features: in Russia, as in some other countries, the main source of infection can be identified. Moscow represents such a source in Russia due to serving as the largest transport hub in the country.Methods. Mathematical modeling and data analysis methods are used.Results. A predicted time lag between peaks of daily infections in Russia and Moscow is confirmed. Identified invariant parameters for COVID-19 epidemic waves can be used to predict the spread of the disease. The checks were carried out for the wave sequence for which predictions were made about the development of infection for Russia and when the recession following peak would occur. These forecasts for all waves were confirmed from the third to the last sixth waves to confirm the found pattern, which can be important for predicting future events.Conclusions. The confirmed forecasts for the timing and rate of the recession can be used to make good predictions about the fifth and sixth waves of infection of the Omicron variant of the COVID-19 virus. Earlier predictions were confirmed by the statistical data.
Restoration of a blurred photographic image of a moving object obtained at the resolution limit
Authors: Fedorov V. B. , Kharlamov S. G. , Starikovskiy A. I. 
Published: August 2023

Objectives. When processing images of the Earth’s surface obtained from satellites, the problem of restoring a blurry image of a moving object is of great practical importance. The aim of this work is to study the possibility of improving the quality of restoration of blurry images obtained at the limit of the resolution of the camera.Methods. Digital signal processing methods informed by the theory of incorrect and ill-conditioned problems were used.Results. The proposed method for restoring a blurred photographic image of a moving object differs from traditional approaches in that the discrete convolution equation, to which the problem of restoring a blurred image is reduced, is obtained by approximating the corresponding integral equation based on the Kotelnikov interpolation series rather than on the traditional basis of the quadrature formula. In the work, formulas are obtained for calculating the kernel of the convolution obtained using the Kotelnikov interpolation series. The discrete convolution inversion problem, which belongs to the class of ill-posed problems, requires regularization. Results of traditional approaches to restoring blurred images using the quadrature formula with Tikhonov regularization and the proposed method based on the Kotelnikov interpolation series are compared. Although the quality of the blurred image restoration is almost the same in both cases, in the quadrature formula the blur value is expressed as an integer number of pixels, while, when using the Kotelnikov series, this value can also be specified in fractions of a pixel.Conclusions. The expediency of discretizing the convolution describing the image distortion of the blur type on the basis of the Kotelnikov interpolation series when processing a blurred image obtained at the limit of the resolution of the camera is demonstrated. In this case, the amount of blur can be expressed in fractions of a pixel. This situation typically arises when processing satellite photography of the Earth’s surface.
Pengaruh Pendidikan dan Ekonomi Orang Tua Terhadap Minat ke Perguruan Tinggi Siswa MA Bahrul Ulum Kupang Jetis
Authors: HA Buro Hasan 
Published: August 2023

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh tingkat pendidikan dan ekonomi orang tua terhadap minat anak untuk melanjutkan ke perguruan tinggi di MA. Bahrul Ulum Kupang Jetis Mojokerto. Populasi penelitian dalam penyusunan skripsi ini adalah siswa kelas XII MA. Bahrul Ulum Kupang Jetis Mojokerto Tahun Pelajaran 2023/2024 yang berjumlah 65 siswa. Dari jumlah populasi yang berjumlah 65 siswa maka secara otomatis diambil secara keseluruhan untuk dijadikan sampel, maka jumlah sampel dalam penelitian ini adalah 65 siswa. Peneliti menggunakan teknik analisis regresi linear sederhana. Hasil penelitian menunjukkan terdapat pengaruh positif yang signifikan tingkat pendidikan dan ekonomi orang tua terhadap minat anak untuk melanjutkan ke perguruan tinggi pada MA. Bahrul Ulum Kupang Jetis Mojokerto Tahun Pelajaran 2023/2024.
A Statistical Analysis of Positive Excess Mortality at Covid-19 in 2020-2021
Authors: Raihen Md Nurul , Akter Sultana , Tabassum Fariha , Jahan Farjana , Sardar Md Nazmul 
Published: August 2023

When it comes to making assessments about public health, the mortality rate is a very important factor. The COVID-19 pandemic has exacerbated well-known biases that affect the measurement of mortality, which varies with time and place. The COVID-19 pandemic took the world off surveillance, and since the outbreak, it has caused damage that many would have thought unthinkable in the present era. By estimating excess mortality for 2020 and 2021, we provide a thorough and consistent evaluation of the COVID-19 pandemic's effects. Excess mortality is a term used in epidemiology and public health to describe the number of fatalities from all causes during a crisis that exceeds what would be expected under 'normal' circumstances. Excess mortality has been used for thousands of years to estimate health emergencies and pandemics like the 1918 "Spanish Flu"6. Positive excess mortality occurs when actual deaths exceed previous data or recognized patterns. It could demonstrate how a pandemic affects the mortality rate. The estimates of positive excess mortality presented in this research are generated using the procedure, data, and methods described in detail in the Methods section and briefly summarized in this study. We explored different regression models in order to find the most effective factor for our estimates. We predict the pandemic period all-cause deaths in locations lacking complete reported data using the Poisson, Negative Binomial count framework. By overdispersion test, we checked the assumption of the Poisson model, and then we chose the negative binomial as a good fitting model for this analysis through Akaike Information Criteria (AIC) and Standardized residual plots, after that checking the P-value<0.05; we found some significant predictors from our choosing model Negative binomial model, and the coefficient of all predictors gave the information that some factors have a positive effect, and some has a negative effect at positive excess mortality at COVID-19 (2020-2021).
Evaluation of Hysteroscopic Findings and Histopathologic Report of Endometrium in Postmenopausal Bleeding
Authors: Begum Monowara , Khatun Sabera , Begum Shirin Akter , Amatullah Mehriban , Mahmud Tasfia , Ara Rifat , Nabi Mahmud-Un , Khatoon Farhana , Nazneen Touhida , Ferdous Jannatul 
Published: August 2023

Background: Women with postmenopausal bleeding have 10%-15% chance of having endometrial carcinoma and therefore the diagnostic work is aimed at excluding uterine malignancy. For accurate diagnosis of cause of postmenopausal bleeding, endometrial abnormalities can be assessed by hysteroscopy and hysteroscopy directed biopsy or fractional curettage.
Objective: To compare the hysteroscopic findings with histopathologic report of endometrium in postmenopausal bleeding.
Methods: Cross sectional study was conducted in the department of gynaecological oncology in Bangabandhu Sheikh Mujib Medical University over 1 year from June 2019 to May 2020. Thirty women with the complaints of postmenopausal bleeding were enrolled. Each women underwent hysteroscopic evaluation and endometrial tissue was obtained by hysteroscopy directed biopsy as well as fractional curettage in some cases, then sent for histopathology. Results were analyzed to find out sensitivity, specificity, accuracy, positive predictive value and negative predictive value of hysteroscopy, taking histopathological diagnosis as gold standard. Analysis was carried out by using SPSS version 26.
Results: Hysteroscopic examination findings and histopathology of endometrium in 30 postmenopausal women, 11(36.6%) cases were found normal both on hysteroscopy and histopathology, among them 4(13.3%) cases were proliferative endometrium, 1(3.3%) was secretory endometrium and 5(16.6%) cases were found atrophic endometrium and 1(3.3%) tissue was insufficient. Hysteroscopic view of normal endometrium showed a sensitivity 100%, specificity 100%, positive predictive value 100%, negative predictive value 100% and accuracy 100%. For Endometrial polyp showed sensitivity, specificity, positive predictive value, negative predictive value and accuracy 100%respectively. For Hyperplasia, hysteroscopy showed sensitivity 100%, specificity 96.2%, positive predictive value 80%, negative predictive value 100% and accuracy 96.7%. Endometrial carcinoma was found in 3(10%) cases and showed sensitivity of 100%, specificity of 96.3%, positive predictive value 75.0%, negative predictive value 100% and accuracy 96.7%. For the atrophic endometrium, sensitivity (100%), specificity (96.0%), positive predictive value (83.3%), negative predictive value (100%) and accuracy (96.7%). 1(3.3%) had in situ endometrial carcinoma and 2(6.6%) had adenomyosis on histopathology.
Conclusion: The study concludes that hysteroscopy and directed biopsy or fractional curettage is a highly accurate, sensitive, specific, positive predictive value and negative predictive value for diagnosis of cause of postmenopausal bleeding.
Bangladesh Medical Res Counc Bull 2023; 49(1): 1-14
New insights learned from the pulmonary to systemic blood flow ratio to predict the outcome in patients with hypoplastic left heart syndrome in the pre-Glenn stage: a single-center study
Authors: Mini Nathalie , Zartner Peter A. , Schneider Martin B. E. 
Published: August 2023

BackgroundTo the best of our knowledge, no study has been made until now to determine whether the ratio between pulmonary and systemic blood flow (Qp/Qs) in the pre-stage II (PS2) or pre-Glenn stage can predict the outcome in patients with hypoplastic left heart syndrome (HLHS) who underwent Norwood (NW) palliation.Patients and methodsFrom January 2016 to August 2022, 80 cardiac catheterizations in 69 patients with HLHS in NW palliation stage with modified Blalock–Taussig shunt (MBTS) were retrospectively recruited. The Qp/Qs was measured under stable conditions using the Fick formula. None of the patients were intubated. Patients were divided into two groups: Group 1 included patients who underwent planned cardiac catheterization (n = 56), and Group 2 had unplanned examination (n = 13), in which the indication for cardiac catheterization was desaturation in 11 patients and pulmonary over-circulation in two. The composite primary outcome was defined as accomplishing the planned operations (Glenn and Fontan) with freedom from death and reoperation, referring to palliative therapy or heart transplantation. The secondary outcome was freedom from transcatheter intervention in MBTS or pulmonary arteries.ResultsThe median follow-up was 48 months (range 6–72 months). The median value of Qp/Qs in Group 1 was 1.75 (range 1.5–2.2). In Group 2, the 11 patients with desaturation, the median value of Qp/Qs was 1.25 (range 0.9–1.45). The two patients with suspected pulmonary overcalculation showed Qp/Qs of 2.3 and 2.5, respectively; a reduction of the shunt size was required. Approximately 96.4% of patients in Group 1 achieved the primary outcome compared with only 30.7% in Group 2. The need for reintervention was 1.8% in Group 1 compared with 61.3% in Group 2. There is a significant relationship between Qp/Qs and the impaired outcome (death, palliative therapy, or heart transplantation) with a p-value of 0.001, a relative risk factor of 3.1, and a 95% confidence interval of 1.4–7.1. No significant relationship between the Qp/Qs and the size of MBTS (p-value of 0.073) was noted.ConclusionThe Qp/Qs in PS2 can predict outcomes in patients with HLHS in Norwood stage with MBTS. The Qp/Qs between 1.5 and 2.2 with a median of 1.75 seems to be optimal in the patients in PS2. Qp/Qs of &lt;1.5 is associated with pulmonary stenosis, shunt stenosis, and pulmonary hypertension.
Teacher sentiments about physical appearance and risk of bullying victimization: the mediating role of quality of student–teacher relationships and psychological adjustment
Authors: Longobardi Claudio , Mastrokoukou Sofia , Fabris Matteo A. 
Published: August 2023

IntroductionThis study investigated the relationship between teachers’ sentiments about physical appearance, student–teacher relationships, psychological adjustment, and the risk of becoming a victim of bullying.MethodParticipants consisted of 995 students (471 females, 47.3%; Mage = 11.3, SDage = 1.49) and 64 teachers (56 females, 87.5%; Mage = 47.59). Students reported their levels of psychological adjustment and their involvement with bullying victimization, while teachers rated relationship quality with their students and reported their sentiments about students’ physical appearance. Teachers’ sentiments about physical appearance were analyzed using the NRC Emotion Lexicon. Correlation and mediation analyses were conducted with Mplus, using a multicategorical antecedent.ResultsResults indicate that teachers’ positive ratings of students’ physical appearance were correlated with close teacher–student relationships, less conflictual relationships, whereas negative ratings were correlated with more conflictual student–teacher relationships and increased bullying victimization risk. Psychological adjustment mediated the relationship, with positive adjustment associated with closer relationships and negative adjustment associated with more conflict.DiscussionThis study suggests the importance of teachers’ sentiments about students’ physical appearance. Positive sentiments promote supportive relationships and reduce the risk of bullying victimization, while negative sentiments erano correlate ad una relazione studente-insegnante netagativa and increased risk of bullying victimization. Promoting positive interactions between teachers and students and addressing appearance biases are critical to creating inclusive educational environments. Further research should focus on understanding and examining the impact of teacher attitudes on student well-being and bullying dynamics.
Pan-cancer analysis of Krüppel-like factor 3 and its carcinogenesis in pancreatic cancer
Authors: Zhu Jinfeng , Teng Hong , Zhu Xiaojian , Yuan Jingxuan , Zhang Qiong , Zou Yeqing 
Published: August 2023

BackgroundKrüppel-like factor 3 (KLF3) is a key transcriptional repressor, which is involved in various biological functions such as lipogenesis, erythropoiesis, and B cell development, and has become one of the current research hotspots. However, the role of KLF3 in the pan-cancer and tumor microenvironment remains unclear.MethodsTCGA and GTEx databases were used to evaluate the expression difference of KLF3 in pan-cancer and normal tissues. The cBioPortal database and the GSCALite platform analyzed the genetic variation and methylation modification of KLF3. The prognostic role of KLF3 in pan-cancer was identified using Cox regression and Kaplan-Meier analysis. Correlation analysis was used to explore the relationship between KLF3 expression and tumor mutation burden, microsatellite instability, and immune-related genes. The relationship between KLF3 expression and tumor immune microenvironment was calculated by ESTIMATE, EPIC, and MCPCOUNTER algorithms. TISCH and CancerSEA databases analyzed the expression distribution and function of KLF3 in the tumor microenvironment. TIDE, GDSC, and CTRP databases evaluated KLF3-predicted immunotherapy response and sensitivity to small molecule drugs. Finally, we analyzed the role of KLF3 in pancreatic cancer by in vivo and in vitro experiments.ResultsKLF3 was abnormally expressed in a variety of tumors, which could effectively predict the prognosis of patients, and it was most obvious in pancreatic cancer. Further experiments verified that silencing KLF3 expression inhibited pancreatic cancer progression. Functional analysis and gene set enrichment analysis found that KLF3 was involved in various immune-related pathways and tumor progression-related pathways. In addition, based on single-cell sequencing analysis, it was found that KLF3 was mainly expressed in CD4Tconv, CD8T, monocytes/macrophages, endothelial cells, and malignant cells in most of the tumor microenvironment. Finally, we assessed the value of KLF3 in predicting response to immunotherapy and predicted a series of sensitive drugs targeting KLF3.ConclusionThe role of KLF3 in the tumor microenvironment of various types of tumors cannot be underestimated, and it has significant potential as a biomarker for predicting the response to immunotherapy. In particular, it plays an important role in the progression of pancreatic cancer.
The IgA of hares (Lepus sp.) and rabbit confirms that the leporids IgA explosion is old and reveals a new case of trans-species polymorphism
Authors: Pinheiro Ana , de Sousa-Pereira Patrícia , Esteves Pedro J. 
Published: August 2023

BackgroundImmunoglobulin A (IgA) is the mammalian mucosal antibody, providing an important line of defense against pathogens. With 15 IgA subclasses, the European rabbit has an extremely complex IgA system, strikingly more complex than most other mammals, which have only one IgA or, in the case of hominoids, two IgA subclasses. Similar to the two hominoid primate IGHA genes, the expansion of the rabbit IGHA genes appears to have begun in an ancestral lagomorph since multiple IgA copies were found by Southern blot analysis for the genera Sylvilagus, Lepus, and Ochotona.ResultsTo gain a better insight into the extraordinary lagomorph IgA evolution, we sequenced, for the first time, expressed IgA genes for two Lepus species, L. europaeus and L. granatensis. These were aligned with the 15 rabbit IgA isotypes, and evolutionary analyses were conducted. The obtained phylogenetic tree shows that the Lepus IgA sequences cluster with and among the rabbit IgA isotypes, and the interspecies and intraspecies nucleotide genetic distances are similar. A comparison of the amino acid sequences of the Lepus and rabbit IgA confirms that there are two trans-species polymorphisms and that the rabbit and Lepus sequences share a common genetic pool. In fact, the main differences between the studied leporids IgAs reside in the characteristics of the hinge region.ConclusionThe Lepus IgA sequences we have obtained strongly suggest that the great expansion of the leporid IGHA genes occurred in a common ancestral species and was then maintained in the descendants. A strong selective pressure caused the extraordinary expansion of the IGHA genes but then subsided, leading to the maintenance of the acquired polymorphisms in the descendants, with little subsequent divergence. This is a unique evolutionary pattern in which an ancient gene expansion has been maintained for approximately 18 million years.