bluuebunny/crossref_metadata_2025_split huggingface dataset:
A good architecture for fast and slow thinking, but exclusivity is exclusively in the past
Authors: Stanovich Keith E. , Toplak Maggie E. 
Published: July 2023

Abstract
No doubt older work in the dual-process tradition overemphasized the importance and frequency of the override function, and the working model in this target article provides a useful corrective. The attempt to motivate the model using the so-called exclusivity assumption is unnecessary, because no recent dual-process model in the reasoning literature has rested strongly on this assumption.
The distinction between long-term knowledge and short-term control processes is valid and useful
Authors: Shiffrin Richard M. , Schneider Walter , Logan Gordon D. 
Published: July 2023

AbstractThe binary distinction De Neys questions has been put forward many times since the beginnings of psychology, in slightly different forms and under different names. It has proved enormously useful and has received detailed empirical support and careful modeling. At heart the distinction is that between knowledge in long-term memory and control processes in short-term memory.
Ancient dolphin genomes reveal rapid repeated adaptation to coastal waters
Authors: Louis Marie , Korlević Petra , Nykänen Milaja , Archer Frederick , Berrow Simon , Brownlow Andrew , Lorenzen Eline D. , O’Brien Joanne , Post Klaas , Racimo Fernando , Rogan Emer , Rosel Patricia E. , Sinding Mikkel-Holger S. , van der Es Henry , Wales Nathan , Fontaine Michael C. , Gaggiotti Oscar E. , Foote Andrew D. 
Published: July 2023

AbstractParallel evolution provides strong evidence of adaptation by natural selection due to local environmental variation. Yet, the chronology, and mode of the process of parallel evolution remains debated. Here, we harness the temporal resolution of paleogenomics to address these long-standing questions, by comparing genomes originating from the mid-Holocene (8610-5626 years before present, BP) to contemporary pairs of coastal-pelagic ecotypes of bottlenose dolphin. We find that the affinity of ancient samples to coastal populations increases as the age of the samples decreases. We assess the youngest genome (5626 years BP) at sites previously inferred to be under parallel selection to coastal habitats and find it contained coastal-associated genotypes. Thus, coastal-associated variants rose to detectable frequencies close to the emergence of coastal habitat. Admixture graph analyses reveal a reticulate evolutionary history between pelagic and coastal populations, sharing standing genetic variation that facilitated rapid adaptation to newly emerged coastal habitats.
Direct evidence of substorm-related impulsive injections of electrons at Mercury
Authors: Aizawa Sae , Harada Yuki , André Nicolas , Saito Yoshifumi , Barabash Stas , Delcourt Dominique , Sauvaud Jean-André , Barthe Alain , Fedorov Andréi , Penou Emmanuel , Yokota Shoichiro , Miyake Wataru , Persson Moa , Nénon Quentin , Rojo Mathias , Futaana Yoshifumi , Asamura Kazushi , Shimoyama Manabu , Hadid Lina Z. , Fontaine Dominique , Katra Bruno , Fraenz Markus , Krupp Norbert , Matsuda Shoya , Murakami Go 
Published: July 2023

AbstractMercury’s magnetosphere is known to involve fundamental processes releasing particles and energy like at Earth due to the solar wind interaction. The resulting cycle is however much faster and involves acceleration, transport, loss, and recycling of plasma. Direct experimental evidence for the roles of electrons during this cycle is however missing. Here we show that in-situ plasma observations obtained during BepiColombo’s first Mercury flyby reveal a compressed magnetosphere hosts of quasi-periodic fluctuations, including the original observation of dynamic phenomena in the post-midnight, southern magnetosphere. The energy-time dispersed electron enhancements support the occurrence of substorm-related, multiple, impulsive injections of electrons that ultimately precipitate onto its surface and induce X-ray fluorescence. These observations reveal that electron injections and subsequent energy-dependent drift now observed throughout Solar System is a universal mechanism that generates aurorae despite the differences in structure and dynamics of the planetary magnetospheres.
Actinide inverse trans influence versus cooperative pushing from below and multi-center bonding
Authors: Motta Laura C. , Autschbach Jochen 
Published: July 2023

AbstractActinide-ligand bonds with high multiplicities remain poorly understood. Decades ago, an effect known as 6p pushing from below (PFB) was proposed to enhance actinide covalency. A related effect—also poorly understood—is inverse trans influence (ITI). The present computational study of actinide-ligand covalent interactions with high bond multiplicities quantifies the energetic contributions from PFB and identifies a hitherto overlooked fourth bonding interaction for 2nd-row ligands in the studied organometallic systems. The latter are best described by a terminal O/N ligand exhibiting quadruple bonding interactions with the actinide. The 4th interaction may be characterized as a multi-center or charge-shift bond involving the trans ligand. It is shown in this work that the 4th bonding interaction is a manifestation of ITI, assisted by PFB, and provides a long-sought missing piece in the understanding of actinide chemistry.
Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males
Authors: Abou-El-Hassan Hadi , Rezende Rafael M. , Izzy Saef , Gabriely Galina , Yahya Taha , Tatematsu Bruna K. , Habashy Karl J. , Lopes Juliana R. , de Oliveira Gislane L. V. , Maghzi Amir-Hadi , Yin Zhuoran , Cox Laura M. , Krishnan Rajesh , Butovsky Oleg , Weiner Howard L. 
Published: July 2023

AbstractTraumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta (γδ) T cells have been shown to affect brain immunopathology in multiple different conditions, however, their role in acute and chronic TBI is largely unknown. Here, we show that γδ T cells affect the pathophysiology of TBI as early as one day and up to one year following injury in a mouse model. TCRδ−/− mice are characterized by reduced inflammation in acute TBI and improved neurocognitive functions in chronic TBI. We find that the Vγ1 and Vγ4 γδ T cell subsets play opposing roles in TBI. Vγ4 γδ T cells infiltrate the brain and secrete IFN-γ and IL-17 that activate microglia and induce neuroinflammation. Vγ1 γδ T cells, however, secrete TGF-β that maintains microglial homeostasis and dampens TBI upon infiltrating the brain. These findings provide new insights on the role of different γδ T cell subsets after brain injury and lay down the principles for the development of targeted γδ T-cell-based therapy for TBI.
Phonemic segmentation of narrative speech in human cerebral cortex
Authors: Gong Xue L. , Huth Alexander G. , Deniz Fatma , Johnson Keith , Gallant Jack L. , Theunissen Frédéric E. 
Published: July 2023

AbstractSpeech processing requires extracting meaning from acoustic patterns using a set of intermediate representations based on a dynamic segmentation of the speech stream. Using whole brain mapping obtained in fMRI, we investigate the locus of cortical phonemic processing not only for single phonemes but also for short combinations made of diphones and triphones. We find that phonemic processing areas are much larger than previously described: they include not only the classical areas in the dorsal superior temporal gyrus but also a larger region in the lateral temporal cortex where diphone features are best represented. These identified phonemic regions overlap with the lexical retrieval region, but we show that short word retrieval is not sufficient to explain the observed responses to diphones. Behavioral studies have shown that phonemic processing and lexical retrieval are intertwined. Here, we also have identified candidate regions within the speech cortical network where this joint processing occurs.
An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models
Authors: Kim Woori , Tripathi Mohit , Kim Chunhyung , Vardhineni Satyapavan , Cha Young , Kandi Shamseer Kulangara , Feitosa Melissa , Kholiya Rohit , Sah Eric , Thakur Anuj , Kim Yehan , Ko Sanghyeok , Bhatia Kaiya , Manohar Sunny , Kong Young-Bin , Sindhu Gagandeep , Kim Yoon-Seong , Cohen Bruce , Rawat Diwan S. , Kim Kwang-Soo 
Published: July 2023

AbstractThe nuclear receptor, Nurr1, is critical for both the development and maintenance of midbrain dopamine neurons, representing a promising molecular target for Parkinson’s disease (PD). We previously identified three Nurr1 agonists (amodiaquine, chloroquine and glafenine) that share an identical chemical scaffold, 4-amino-7-chloroquinoline (4A7C), suggesting a structure-activity relationship. Herein we report a systematic medicinal chemistry search in which over 570 4A7C-derivatives were generated and characterized. Multiple compounds enhance Nurr1’s transcriptional activity, leading to identification of an optimized, brain-penetrant agonist, 4A7C-301, that exhibits robust neuroprotective effects in vitro. In addition, 4A7C-301 protects midbrain dopamine neurons in the MPTP-induced male mouse model of PD and improves both motor and non-motor olfactory deficits without dyskinesia-like behaviors. Furthermore, 4A7C-301 significantly ameliorates neuropathological abnormalities and improves motor and olfactory dysfunctions in AAV2-mediated α-synuclein-overexpressing male mouse models. These disease-modifying properties of 4A7C-301 may warrant clinical evaluation of this or analogous compounds for the treatment of patients with PD.
Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel
Authors: Hu Zhengshan , Zheng Xiangdong , Yang Jian 
Published: July 2023

AbstractCyclic nucleotide-gated (CNG) channels transduce chemical signals into electrical signals in sensory receptors and neurons. They are activated by cGMP or cAMP, which bind to the cyclic nucleotide-binding domain (CNBD) to open a gate located 50-60 Å away in the central cavity. Structures of closed and open vertebrate CNG channels have been solved, but the conformational landscape of this allosteric gating remains to be elucidated and enriched. Here, we report structures of the cGMP-activated human cone photoreceptor CNGA3/CNGB3 channel in closed, intermediate, pre-open and open states in detergent or lipid nanodisc, all with fully bound cGMP. The pre-open and open states are obtained only in the lipid nanodisc, suggesting a critical role of lipids in tuning the energetic landscape of CNGA3/CNGB3 activation. The different states exhibit subunit-unique, incremental and distinct conformational rearrangements that originate in the CNBD, propagate through the gating ring to the transmembrane domain, and gradually open the S6 cavity gate. Our work illustrates a spatial conformational-change wave of allosteric gating of a vertebrate CNG channel by its natural ligand and provides an expanded framework for studying CNG properties and channelopathy.
Identification of breast lesion through integrated study of gorilla troops optimization and rotation-based learning from MRI images
Authors: Si Tapas , Patra Dipak Kumar , Mallik Saurav , Bandyopadhyay Anjan , Sarkar Achyuth , Qin Hong 
Published: July 2023

AbstractBreast cancer has emerged as the most life-threatening disease among women around the world. Early detection and treatment of breast cancer are thought to reduce the need for surgery and boost the survival rate. The Magnetic Resonance Imaging (MRI) segmentation techniques for breast cancer diagnosis are investigated in this article. Kapur’s entropy-based multilevel thresholding is used in this study to determine optimal values for breast DCE-MRI lesion segmentation using Gorilla Troops Optimization (GTO). An improved GTO, is developed by incorporating Rotational opposition based-learning (RBL) into GTO called (GTORBL) and applied it to the same problem. The proposed approaches are tested on 20 patients’ T2 Weighted Sagittal (T2 WS) DCE-MRI 100 slices. The proposed approaches are compared with Tunicate Swarm Algorithm (TSA), Particle Swarm Optimization (PSO), Arithmetic Optimization Algorithm (AOA), Slime Mould Algorithm (SMA), Multi-verse Optimization (MVO), Hidden Markov Random Field (HMRF), Improved Markov Random Field (IMRF), and Conventional Markov Random Field (CMRF). The Dice Similarity Coefficient (DSC), sensitivity, and accuracy of the proposed GTO-based approach is achieved $$87.04\%$$

87.04
%

, $$90.96\%$$

90.96
%

, and $$98.13\%$$

98.13
%

respectively. Another proposed GTORBL-based segmentation method achieves accuracy values of $$99.31\%$$

99.31
%

, sensitivity of $$95.45\%$$

95.45
%

, and DSC of $$91.54\%$$

91.54
%

. The one-way ANOVA test followed by Tukey HSD and Wilcoxon Signed Rank Test are used to examine the results. Furthermore, Multi-Criteria Decision Making is used to evaluate overall performance focused on sensitivity, accuracy, false-positive rate, precision, specificity, $$F_1$$

F
1

-score, Geometric-Mean, and DSC. According to both quantitative and qualitative findings, the proposed strategies outperform other compared methodologies.
Climate, host and geography shape insect and fungal communities of trees
Authors: Franić Iva , Allan Eric , Prospero Simone , Adamson Kalev , Attorre Fabio , Auger-Rozenberg Marie-Anne , Augustin Sylvie , Avtzis Dimitrios , Baert Wim , Barta Marek , Bauters Kenneth , Bellahirech Amani , Boroń Piotr , Bragança Helena , Brestovanská Tereza , Brurberg May Bente , Burgess Treena , Burokienė Daiva , Cleary Michelle , Corley Juan , Coyle David R. , Csóka György , Černý Karel , Davydenko Kateryna , de Groot Maarten , Diez Julio Javier , Doğmuş Lehtijärvi H. Tugba , Drenkhan Rein , Edwards Jacqueline , Elsafy Mohammed , Eötvös Csaba Béla , Falko Roman , Fan Jianting , Feddern Nina , Fürjes-Mikó Ágnes , Gossner Martin M. , Grad Bartłomiej , Hartmann Martin , Havrdova Ludmila , Kádasi Horáková Miriam , Hrabětová Markéta , Justesen Mathias Just , Kacprzyk Magdalena , Kenis Marc , Kirichenko Natalia , Kovač Marta , Kramarets Volodymyr , Lacković Nikola , Lantschner Maria Victoria , Lazarević Jelena , Leskiv Marianna , Li Hongmei , Madsen Corrie Lynne , Malumphy Chris , Matošević Dinka , Matsiakh Iryna , May Tom W. , Meffert Johan , Migliorini Duccio , Nikolov Christo , O’Hanlon Richard , Oskay Funda , Paap Trudy , Parpan Taras , Piškur Barbara , Ravn Hans Peter , Richard John , Ronse Anne , Roques Alain , Ruffner Beat , Santini Alberto , Sivickis Karolis , Soliani Carolina , Talgø Venche , Tomoshevich Maria , Uimari Anne , Ulyshen Michael , Vettraino Anna Maria , Villari Caterina , Wang Yongjun , Witzell Johanna , Zlatković Milica , Eschen René 
Published: July 2023

AbstractNon-native pests, climate change, and their interactions are likely to alter relationships between trees and tree-associated organisms with consequences for forest health. To understand and predict such changes, factors structuring tree-associated communities need to be determined. Here, we analysed the data consisting of records of insects and fungi collected from dormant twigs from 155 tree species at 51 botanical gardens or arboreta in 32 countries. Generalized dissimilarity models revealed similar relative importance of studied climatic, host-related and geographic factors on differences in tree-associated communities. Mean annual temperature, phylogenetic distance between hosts and geographic distance between locations were the major drivers of dissimilarities. The increasing importance of high temperatures on differences in studied communities indicate that climate change could affect tree-associated organisms directly and indirectly through host range shifts. Insect and fungal communities were more similar between closely related vs. distant hosts suggesting that host range shifts may facilitate the emergence of new pests. Moreover, dissimilarities among tree-associated communities increased with geographic distance indicating that human-mediated transport may serve as a pathway of the introductions of new pests. The results of this study highlight the need to limit the establishment of tree pests and increase the resilience of forest ecosystems to changes in climate.
Differences in carbonate chemistry up-regulation of long-lived reef-building corals
Authors: Canesi Marine , Douville Eric , Montagna Paolo , Taviani Marco , Stolarski Jarosław , Bordier Louise , Dapoigny Arnaud , Coulibaly Gninwoyo Eric Hermann , Simon Anne-Catherine , Agelou Mathieu , Fin Jonathan , Metzl Nicolas , Iwankow Guillaume , Allemand Denis , Planes Serge , Moulin Clémentine , Lombard Fabien , Bourdin Guillaume , Troublé Romain , Agostini Sylvain , Banaigs Bernard , Boissin Emilie , Boss Emmanuel , Bowler Chris , de Vargas Colomban , Flores Michel , Forcioli Didier , Furla Paola , Gilson Eric , Galand Pierre E. , Pesant Stéphane , Sunagawa Shinichi , Thomas Olivier P. , Vega Thurber Rebecca , Voolstra Christian R. , Wincker Patrick , Zoccola Didier , Reynaud Stéphanie 
Published: July 2023

AbstractWith climate projections questioning the future survival of stony corals and their dominance as tropical reef builders, it is critical to understand the adaptive capacity of corals to ongoing climate change. Biological mediation of the carbonate chemistry of the coral calcifying fluid is a fundamental component for assessing the response of corals to global threats. The Tara Pacific expedition (2016–2018) provided an opportunity to investigate calcification patterns in extant corals throughout the Pacific Ocean. Cores from colonies of the massive Porites and Diploastrea genera were collected from different environments to assess calcification parameters of long-lived reef-building corals. At the basin scale of the Pacific Ocean, we show that both genera systematically up-regulate their calcifying fluid pH and dissolved inorganic carbon to achieve efficient skeletal precipitation. However, while Porites corals increase the aragonite saturation state of the calcifying fluid (Ωcf) at higher temperatures to enhance their calcification capacity, Diploastrea show a steady homeostatic Ωcf across the Pacific temperature gradient. Thus, the extent to which Diploastrea responds to ocean warming and/or acidification is unclear, and it deserves further attention whether this is beneficial or detrimental to future survival of this coral genus.
Annular multi-focal-phase mask multiplexing based large depth of field imaging by interferenceless coded aperture correlation holography
Authors: Liu Chao , Wan Yuhong , Ma Teng , Ma Tian , Man Tianlong 
Published: July 2023

AbstractExtending depth-of-field (DOF) of the imaging system without modifying the structure and sacrificing imaging performances of the optical system is of great significance to broaden the capability and application of the imaging system. In this paper, the interferenceless coded aperture correlation holography(I-COACH) is developed to be a large-depth incoherent imaging system by employing an annular multi-focal coded phase mask (AM-CPM). Based on the analyses of axial defocus characteristics in I-COACH, the defocus compensation function is defined, the AM-CPM is designed and multiplexed on the system optical pupil, which plays the role of a gradual lens. In AM-CPM, multi-annular zones with different focal lengths are used to compensate different axial defocus aberrations and adjacent annular zones have symmetric axial defocus aberration correction capability according to the imaging characteristics of the system. The simulations and experimental results fully demonstrate that the axial point spread function distribution of the system obtained by AM-CPM is continuous and the development method enables the extension of the DOF of the I-COACH system by only single exposure point spread hologram. This solution is expected to provide great potential in the field of microscopic imaging and other fields of that based on I-COACH system.
A precise estimation for vibrational energies of diatomic molecules using the improved Rosen–Morse potential
Authors: Abu-Shady M. , Khokha E. M. 
Published: July 2023

AbstractIn the context of the generalized fractional derivative, novel solutions to theD-dimensional Schrödinger equation are investigated via the improved Rosen-Morse potential (IRMP). By applying the Pekeris-type approximation to the centrifugal term, the generalized fractional Nikiforov-Uvarov method has been used to derive the analytical formulations of the energy eigenvalues and wave functions in terms of the fractional parameters inD-dimensions. The resulting solutions are employed for a variety of diatomic molecules (DMs), which have numerous uses in many fields of physics. With the use of molecular parameters, the IRMP is utilized to reproduce potential energy curves for numerous DMs. The pure vibrational energy spectra for several DMs are determined using both the fractional and the ordinary forms to demonstrate the effectiveness of the method utilized in this work. As compared to earlier investigations, it has been found that our estimated vibrational energies correspond with the observed Rydberg-Klein-Rees (RKR) data much more closely. Moreover, it is observed that the vibrational energy spectra of different DMs computed in the existence of fractional parameters are superior to those computed in the ordinary case for fitting the observed RKR data. Thus, it may be inferred that fractional order significantly affects the vibrational energy levels of DMs. Both the mean absolute percentage deviation (MAPD) and average absolute deviation (AAD) are evaluated as the goodness of fit indicators. According to the estimated AAD and MAPD outcomes, the IRMP is an appropriate model for simulating the RKR data for all of the DMs under investigation.