bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Phosphate‐based Organic Polymer Nanocontainer Efficiently Hosts Ag/Ru Nanoparticles for Heterogeneous Catalytic Reduction of Nitroaromatics and Oxidation of Benzyl Alcohols
Authors: Bera Sudharanjan , Banerjee Flora , Samanta Suman Kalyan 
Published: April 2023

AbstractOrganic polymer networks (OPNs) are an interesting class of materials showing immense potential for supporting various metal nanoparticles for their heterogeneous catalytic applications. Herein, we delineate a protocol for generating metal‐based nanoparticles including silver nanoparticles (AgNPs) and ruthenium nanoparticles (RuNPs) within a phosphate‐based OPN (OPN‐4) prepared by the copolymerization of phosphoryl chloride and 1,3,5‐(4‐hydroxyphenyl)benzene in order to generate the heterogeneous catalysts, M@OPN‐4 (M=Ag/Ru). OPN‐4 emerged as an excellent host for the loading of these nanoparticles. These nanoparticles loaded OPN‐4 were characterized by several techniques including scanning and transmission electron microscopy (SEM, TEM), thermogravimetric analysis (TGA), X‐ray photoelectron spectroscopy (XPS), powder X‐ray diffraction (PXRD), and FTIR studies. M@OPN‐4 acted as the heterogeneous catalysts towards various organic reactions including reduction of nitroaromatics (Ag@OPN‐4) and oxidation of benzyl alcohols (Ru@OPN‐4) furnishing desired products from moderate to excellent yield with high selectivity over a broad range of substrates. They also exhibited easy recovery via filtration and reuse for up to five cycles without losing their catalytic activity significantly. Above all, the as synthesized catalysts were found to possess air and moisture endurance, high cost‐effectiveness and robust behavior. Thus, the OPN‐4 nanocontainer could establish itself as a versatile host towards different metal nanoparticles attributed to electron donating phosphate moiety.
The inequalities reduction through healthcare decentralisation in low‐middle income countries: The case of Tunisia
Authors: Giusti Martina , Romolini Alberto , Persiani Niccolò 
Published: April 2023

AbstractHealthcare decentralisation is a model of public service management founds on the wider distribution of the decisional power about healthcare. The decision power is split by central government also with the local health authorities. Since the 1980s, at worldwide level this reform has being applied for guaranteeing equity, efficiency, quality and financial sustainability in the healthcare services provision. In the last years, healthcare decentralisation is happening especially in low‐middle income countries. With regard to the analysis of the effectiveness of decentralisation in healthcare, the obtained results are mixed. This study aims to investigate the contribution of management in the first steps of decentralisation's implementation for reducing health inequalities in Tunisia. To have the management's point of view, a survey was sent to all directors of the Tunisian regional hospitals. Health management was able to offer operative and timely solutions to the homogenisation and the improvement of healthcare services supply in Tunisia. For healthcare managers the guarantee of an equal and effective Tunisian healthcare system is into the application of a differentiated decentralisation. The differentiated decentralisation of healthcare system allows to resolve regional issues in Tunisia. These interventions permit to obtain consistent positive results about the satisfaction of Tunisian population health needs. The differentiated decentralisation of healthcare system could also be useful for similar countries, for example, of MENA are of low‐middle income countries.
Clinical outcomes of fetuses with chromosome 16 short arm copy number variants
Authors: Kang Jessica , Lee Chien‐Nan , Su Yi‐Ning , Tai Yi‐Yun , Chen Chih‐Ling , Chen Han‐Ying , Lin Shin‐Yu 
Published: April 2023

AbstractBackgroundThe short arm of chromosome 16 consists of several copy number variants (CNVs) that are crucial in neurodevelopmental disorders; however, incomplete penetrance and diverse phenotypes after birth aggravate the difficulty of prenatal genetic counseling.MethodsWe screened 15,051 pregnant women who underwent prenatal chromosomal microarray analysis between July 2012 and December 2017. Patients with positive array results were divided into four subgroups based on the type of mutation identified on screening (16p13.3, 16p13.11, 16p12.2, and 16p11.2), and the maternal characteristics, prenatal examinations, and postnatal outcomes of different cases were reviewed.ResultsChromosome 16 CNVs were identified in 34 fetuses, including four with 16p13.3 CNVs, 22 with 16p13.11 CNVs, two with 16p12.2 microdeletions, and six with 16p11.2 CNVs. Of the 34 fetuses, 17 delivered without early childhood neurodevelopmental disorders, three developed neurodevelopmental disorders during childhood, and 10 were terminated.ConclusionIncomplete penetrance and variable expressivity make prenatal counseling challenging. Most cases with inherited 16p13.11 microduplication were reported to have normal development in early childhood, and we also report a few cases of de novo 16p CNVs without further neurodevelopmental disorders.
Hotspots and trends in frozen soils research in 2010–2019
Authors: Liu Wenhao , Li Ren , Shi Xiaoqian , Wu Tonghua , Wu Xiao Dong 
Published: April 2023

AbstractIn the context of climate change, research on frozen soils has attracted much attention in recent years, and numerous research papers have been published on these topics in the last decade. However, the present status and developmental trends in frozen soils research have not been reported systematically. Herein, a bibliometric analysis was conducted using 7,108 research papers on frozen soils published between 2010 and 2019. The results indicate that: (a) although the number of articles published increased from 432 in 2010 to 1,066 in 2019, the average number of citations per paper reached a maximum of 5.40 in 2014, and subsequently decreased to 2.99 in 2019; (b) China, the USA, and Canada ranked first to third in terms of total papers; (c) the most popular author keywords were boreal, tundra, Landsat, lakes, decomposition, dissolved organic carbon, permafrost thaw, and carbon cycle; and (d) the five most popular research topics in 2010–2019 were the characteristics and factors influencing frozen soils, the Arctic carbon cycle under the background of its complex environment, permafrost changes on the Qinghai–Tibet Plateau in the context of climate change, ancient frozen soils in various historical periods, and frozen soils in the Arctic.
Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota‐host co‐metabolism of branched‐chain amino acid
Authors: Zheng Xiao‐xiao , Li Ding‐xiang , Li Ya‐ting , Chen Yu‐lang , Zhao Yan‐lin , Ji Shuai , Guo Meng‐zhe , Du Yan , Tang Dao‐Quan 
Published: April 2023

AbstractElevations in circling branched‐chain amino acids (BCAAs) levels associated with insulin resistance and type 2 diabetes mellitus (T2DM). Morus alba L. water extracts (MLE) show hypoglycemic function, but the precise mechanism remains obscure. This study is designed to investigate the association of the antidiabetes effect of MLE with the BCAAs co‐metabolism modulated by host and gut microbiota. Tissue‐specific expressions of BCAA‐catabolizing enzymes were detected by RT‐PCR and western blot, respectively. The components of the intestinal microflora were analyzed by high‐throughput 16S rRNA gene sequencing. The results showed that MLE administration improved blood glucose and insulin level, decreased inflammatory cytokines expression, and lowered serum and feces BCAAs levels. Furthermore, MLE reversed the abundance changes of the bacterial genera correlated with serum and feces BCAAs, such as Anaerovorax, Bilophila, Blautia, Colidextribacter, Dubosiella, Intestinimonas, Lachnoclostridium, Lachnospiraceae_NK4A136, Oscillibacter, and Roseburia. Functionality prediction indicated that MLE potentially inhibited bacterial BCAAs biosynthesis, and promoted the tissue‐specific expression of BCAAs catabolic enzyme. More importantly, MLE had obvious impacts on BCAA catabolism in germ‐free‐mimic T2DM mice. Those results indicated that MLE improving T2DM‐related biochemical abnormalities is associated with not only gut microbiota modification but also the tissue‐specific expression of BCAAs catabolic enzyme.
The Plastic treaty: What is in it for Africa?
Authors: Shomuyiwa Deborah Oluwaseun , Onukansi Francisca Ogochukwu , Ivanova Maria , Lucero‐Prisno Don Eliseo 
Published: April 2023

AbstractThe new plastic treaty, slated for 2024, represents a shift in the global fight to address environmental pollution and degradation. The international agreement, unlike previous resolutions, covers the lifecycle of plastics and represents a legally binding instrument for ending plastic pollution across all ecosystems. Plastic waste contamination poses significant challenges to African nations. It challenges food security, ecological variation and economic development. The African region has been identified with a high level of enactment of waste management policies but a deficiency of sustainable measures to adopt and implement these policies. The new treaty could provide an instrument for collaboration and innovation and set the stage for Africa to transition to a sustainable plastics environment that promotes zero‐waste.
A copula‐based reliability model for phased mission systems with dependent components
Authors: Li Xiangyu , Zhan Kai , Xiong Xiaoyan , Vu Tuong Quyen 
Published: April 2023

AbstractRecently, researches on the reliability analysis of phased mission systems (PMSs) are very popular. And most of the existing research on PMSs assumed that all the components are statistically independent on each other, which is not meet the engineering reality. The system structure changes from phase to phase in the PMSs, so the dependency among components may also change in different phases. Meanwhile, the well‐known phase dependency is also existing in the system reliability modeling. To model the varying dependency among components and phase dependency at the same time, a copula‐based method is proposed for the reliability analysis of PMS with correlated components. Firstly, the system reliability of multi‐state PMS with dependent components is evaluated by different copula functions. Then, multiple indicators are used to select the optimal copula functions for different phases. And an engineering case is illustrated to show the proposed copula‐based method.
Achieving corporate sustainable development through social responsibility, green activities, and stakeholders management: A multidirectional cause analysis
Authors: Liu Yiying , Niu Juanjuan , Zhou Yongbin , Huang Ruoqi 
Published: April 2023

AbstractThe study aims to explore insights into stakeholder engagement that how it amplifies consumers' engagement toward organizations. This study attempts to meet the literature gap by investigating the nexus among corporate social responsibility, green purchase behavior, stakeholder knowledge, and stakeholder trust by considering the Chinese Z‐generation drawing on stakeholder theory. Structure equation modeling was majorly equipped to obtain the connections among adopted variables to compute the proposed relationships using the sample size of 611 (n = 611). First, a positive relationship was found between corporate social responsibility (CSR) and green purchase behavior. Second, the study uncovered the significant connection between CSR and consumer knowledge. Finally, the study confirmed the positive relationship between CSR and consumer trust toward the organizations. This study endows with numerous interesting and fruitful implications for managers, practitioners, and policymakers. The current study additionally endeavors to highlight the notion of CSR in terms of stakeholders' engagement and how a firm can strengthen relationships with its stakeholders such as consumers. Besides, this study bears some shortcomings and several potentials for future scholars to consider similar themes to validate the outcomes within the Chinese market and across the world.
Ultrasound‐Assisted Zinc‐Catalyzed One‐pot Synthesis of Enaminoketoesters
Authors: Itage Shivanand V. , Bhosle Siddhanath D. , Jadhav Krishna A. , Bhosale Rajesh S. , Yadav J. S. 
Published: April 2023

AbstractHerein we report an ultrasound‐assisted zinc‐catalyzed solvent‐free process for the synthesis of enaminoketoesters from 1,3 dicarbonyl compounds, N, N‐Dimethylformamide dimethyl acetal (DMFDMA) and various amines with good to excellent yields. This methodology is very much applicable for primary aliphatic, aromatic and secondary alicyclic amines bearing different functional groups. The present work offers the following merits such as inexpensive reagents, one‐pot reaction, eco‐friendly and tolerance to different functional groups with short reaction time.
Experimental and DFT investigations of SERS Profile of a Bioactive Hydroxybenzamide Derivative
Authors: Al‐Otaibi Jamelah S. , Mary Yohannan Sheena , Mary Y. Shyma , Krátký Martin , Vinsova Jarmila , Gamberini Maria Cristina 
Published: April 2023

AbstractSurface enhanced Raman scattering (SERS) experiments were used to evaluate the adsorption and orientation of 5‐bromo‐N‐[4‐bromo‐3‐(trifluoromethyl)phenyl]‐2‐hydroxybenzamide (BTB) adsorbed on silver colloid and the results were compared to normal Raman spectra of BTB. Density functional theory (DFT) analysis was used to theoretically validate the observed spectra of BTB. BTB and BTB‐Ag6 molecular structures were optimized at first. The BTB molecule is adsorbed with the Ag6 with energy of −10.67 eV through atoms, O9, F22 and Br17 atoms. The charge transfer interaction between Ag6 clusters and BTB, which lead to BTB adsorption on Ag6 metal clusters, is confirmed by the Frontier Molecular Orbitals (FMOs) study. The BTB chemisorbed on silver with a tilted orientation, as confirmed by SERS spectral analysis and the accompanying results were theoretically justified.
Asymmetric Synthesis of Contact Pheromone Component of Xylotrechus colonus and Its Analogues
Authors: Yuan Chaonan , Wu Jianwei , Yu Shihang , Bian Qinghua , Wang Min , Liu Dan , Zhong Jiangchun 
Published: April 2023

AbstractXylotrechus colonus is an abundant wood‐boring pest of woody plants. 3‐Methylpentacosane was identified as the component of its contact pheromone. A novel and efficient asymmetric synthesis of (S)‐3‐methylpentacosane and its analogues was developed using (S)‐2‐methylbutan‐1‐ol as chiral source. The key of this approach included Wittig coupling of chiral phosphonium salt with aldehyde, Pd‐catalyzed hydrogenation and Appel reaction. Our synthesis would be helpful for the control and detect of this pest.
Visible‐Light‐Promoted Fluoroalkylative Cyclization of N‐Allyl‐4,5‐dihydro‐3H‐1‐benzazepin‐2‐amines: Effective Synthesis of Fluoroalkylated Imidazobenzazepines
Authors: Danyliuk Ivanna Yu. , Tolmachova Valentyna S. , Shishkina Svitlana V. , Vovk Mykhailo V. 
Published: April 2023

AbstractA new preparatively convenient approach to the synthesis of biopromising 1‐fluoroalkyl‐substituted 2,4,5,6‐tetrahydro‐1H‐imidazo[1,2‐a][1]benzazepines has been developed, based on the chemoselective photoreduction‐catalyzed fluoroalkylation cyclization of N‐allyl‐4,5‐dihydro‐3H‐1‐benzazepin‐2‐amines in the presence of fluorescein as an organocatalyst. The use of comparatively inexpensive perfluoroalkyl iodides (RfI), mild reaction conditions and a wide range of substituents introduced make this method very attractive for the preparation of imidazobenzazepines with a variety of fluorinated moieties.
Heavy Metals Removal Using Nano‐Hydroxyapatite Extracted from Cattle Bones
Authors: Aissa Abdallah , Othmani Masseoud 
Published: April 2023

AbstractLocal cattle (lamb and camel) bones were used as a starting material to obtain pure nano‐hydroxyapatite n‐HAp. Extraction of nano‐HAp is done at 700 °C and 900 °C calcination temperatures, followed by some characterization technics such as FTIR spectroscopy, UV‐visible spectroscopy, XRD diffraction pattern, SEM and EDX analyzes. All the technics used have confirmed that calcination at these temperatures leads to a material in which pure hydroxyapatite is the only crystallographic phase. The heavy metals removal capacity of n‐HAp applied to Cu2+ and Co2+ from aqueous solutions was exanimated and compared. The obtained results were interpreted and compared based on; (i) the calcination temperature, (ii) the nature of the adsorbed cation on the nano‐hydroxyapatite surface and (iii) the nature of the adsorbent.
Ce Site in Amorphous Iron Oxyhydroxide Nanosheet toward Enhanced Electrochemical Water Oxidation
Authors: Dajan Fekadu Tsegaye , Sendeku Marshet Getaye , Wu Binglan , Gao Ning , Anley Eyaya Fekadie , Tai Jing , Zhan Xueying , Wang Zhenxing , Wang Fengmei , He Jun 
Published: April 2023

AbstractIron oxyhydroxide has been considered an auspicious electrocatalyst for the oxygen evolution reaction (OER) in alkaline water electrolysis due to its suitable electronic structure and abundant reserves. However, Fe‐based materials seriously suffer from the tradeoff between activity and stability at a high current density above 100 mA cm−2. In this work, the Ce atom is introduced into the amorphous iron oxyhydroxide (i.e., CeFeOxHy) nanosheet to simultaneously improve the intrinsic electrocatalytic activity and stability for OER through regulating the redox property of iron oxyhydroxide. In particular, the Ce substitution leads to the distorted octahedral crystal structure of CeFeOxHy, along with a regulated coordination site. The CeFeOxHy electrode exhibits a low overpotential of 250 mV at 100 mA cm−2 with a small Tafel slope of 35.1 mVdec−1. Moreover, the CeFeOxHy electrode can continuously work for 300 h at 100 mA cm−2. When applying the CeFeOxHy nanosheet electrode as the anode and coupling it with the platinum mesh cathode, the cell voltage for overall water splitting can be lowered to 1.47 V at 10 mA cm−2. This work offers a design strategy for highly active, low‐cost, and durable material through interfacing high valent metals with earth‐abundant oxides/hydroxides.
Improved simplified constitutive tensile model for fiber‐reinforced concrete
Authors: Vandevyvere Brecht , Vandewalle Lucie , Li Jiabin 
Published: April 2023

AbstractDue to the low strain capacity and the weak crack resistance of concrete, fibers are commonly added to concrete to increase its tensile resistance. The most recent standardized constitutive tensile model is given in the fib Model code 2010, which is based on a simplified stress profile at serviceability limit state (SLS) and ultimate limit state (ULS). However, in current research, an improved stress profile at ULS is proposed. Consequently, three new constitutive tensile models, which are valued for a specific FRC class, are developed. Those models are constructed with the test data of fiber‐reinforced concrete with natural aggregates (FR‐NAC) and three types of recycled aggregates (FR‐RAC). In addition, macro glass fibers and macro polypropylene fibers are used. The test data indicate that the lower concrete Young's modulus of FR‐RAC, as well as the crack growth resistance due to plastic work of the recycled concrete mixtures, result in an increased residual tensile strength at SLS and ULS. The residual tensile strength at 2.5 mm CMOD () of the normal recycled aggregate concrete (nRAC) mixture with 0.75 V% glass fibers is 0.95 MPa, while the FR‐NAC mixture with the same fiber content only indicates a ‐value of 0.43 MPa. Consequently, higher linear postcracking stresses are observed for the FR‐RAC mixtures, especially for the FR‐RAC mixtures with 0.75 V% glass fibers and the lower quality of recycled aggregates.
Clinical outcome, quality of life, and mental health in long-gap esophageal atresia: comparison of gastric sleeve pull-up and delayed primary anastomosis
Authors: Boettcher Michael , Hauck Marie , Fuerboeter Mareike , Elrod Julia , Vincent Deirdre , Boettcher Johannes , Reinshagen Konrad 
Published: April 2023

Abstract
Introduction
Pediatric surgeons have yet to reach a consensus whether a gastric sleeve pull-up or delayed primary anastomosis for the treatment of esophageal atresia (EA), especially of the long-gap type (LGEA) should be performed. Thus, the aim of this study was to evaluate clinical outcome, quality of life (QoL), and mental health of patients with EA and their parents.

Methods
Clinical outcomes of all children treated with EA from 2007 to 2021 were collected and parents of affected children were asked to participate in questionnaires regarding their Quality of Life (QoL) and their child’s Health-Related Quality of Life (HRQoL), as well as mental health.

Results
A total of 98 EA patients were included in the study. For analysis, the cohort was divided into two groups: (1) primary versus (2) secondary anastomosis, while the secondary anastomosis group was subdivided into (a) delayed primary anastomosis and (b) gastric sleeve pull-up and compared with each other. When comparing the secondary anastomosis group, significant differences were found between the delayed primary anastomosis and gastric sleeve pull-up group; the duration of anesthesia during anastomosis surgery (478.54 vs 328.82 min, p < 0.001), endoscopic dilatation rate (100% vs 69%, p = 0.03), cumulative time spent in intensive care (42.31 vs 94.75 days, p = 0.03) and the mortality rate (0% vs 31%, p = 0.03). HRQoL and mental health did not differ between any of the groups.

Conclusion
Delayed primary anastomosis or gastric sleeve pull-up appear to be similar in patients with long-gap esophageal atresia in many key aspects like leakage rate, strictures, re-fistula, tracheomalacia, recurrent infections, thrive or reflux. Moreover, HrQoL was comparable in patients with (a) gastric sleeve pull-up and (b) delayed primary anastomosis. Future studies should focus on the long-term results of either preservation or replacement of the esophagus in children.
From laboratory to field: laboratory-measured pesticide resistance reflects outcomes of field-based control in the redlegged earth mite, Halotydeus destructor
Authors: Umina Paul A. , McGrane Leo , Thia Joshua A. , Chirgwin Evatt , Hoffmann Ary A. 
Published: April 2023

AbstractResistance to pesticides is typically identified via laboratory bioassays after field control failures are observed, but the results of such assays are rarely validated through experiments under field conditions. Such validation is particularly important when only a low-to-moderate level of resistance is detected in the laboratory. Here we undertake such a validation for organophosphate resistance in the agricultural pest mite Halotydeus destructor, in which low-to-moderate levels of resistance to organophosphorus pesticides have evolved in Australia. Using data from laboratory bioassays, we show that resistance to the organophosphate chlorpyrifos is higher (around 100-fold) than resistance to another organophosphate, omethoate (around 7-fold). In field trials, both these chemicals were found to effectively control pesticide-susceptible populations of H. destructor. However, when applied to a resistant mite population in the field, the effectiveness of chlorpyrifos was substantially decreased. In contrast, omethoate remained effective when tested alone or as a mixture with chlorpyrifos. We also show that two novel (non-pesticide) treatments, molasses and wood vinegar, are ineffective in controlling H. destructor when sprayed to pasture fields at rates of 4 L/ha. These findings suggest a close link between levels of resistance quantified through laboratory bioassays and the field effectiveness of pesticides; however, in the case of H. destructor, this does not necessarily mean all field populations possessing organophosphate resistance will respond similarly given the potentially complex nature of the underlying resistance mechanism(s).