bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women authorship in pain research: A bibliometric analysis from 2002 to 2021
Authors: Zhong Haoyan , Poeran Jashvant , Cozowicz Crispiana , Illescas Alex , Liu Jiabin , Memtsoudis Stavros G. 
Published: June 2023

AbstractObjectivesThere is a lack of data on the distribution of women first and senior authorships in pain journals. Using articles published in top North American pain journals over the past two decades, we sought to describe the prevalence and changes in women representation among first and last authors.MethodsWe retrieved all published research articles in four pain journals (Regional Anesthesia and Pain Medicine, Clinical Journal of Pain, Pain and The Journal of Pain) from 2002 to 2021 using the easyPubMed package. Subsequently, the ‘gender’ package in R was used to determine authors' gender by first names. Trends in gender authorship change over time were assessed.ResultsThe final cohort consisted of 20,981 authors (from an initial total of 11,842 publications and 23,684 authors retrieved). Women authors were more often first compared to senior authors (46.7% vs. 30.5%). The proportion of women first authors (46.2% in 2002 vs. 48.4% in 2021) and women senior authors (22.4% in 2002 vs. 36.3% in 2021) increased over the course of the study period (all p‐value <0.001). The Clinical Journal of Pain having the highest percentage of women authors and Regional Anesthesia and Pain Medicine had the lowest percentage of women authors.DiscussionOur data demonstrated increasing women authorship in pain journals in the past 20 years, largely driven by an increase in first authorships. There still remains a large gap between first and senior authorship, indicative of disparity in the role that women play in research.
Natural flood management: Lessons and opportunities from the catastrophic 2021–2022 floods in eastern Australia
Authors: Fryirs Kirstie , Zhang Nuosha , Ralph Timothy J. , Arash Amir Mohammad 
Published: June 2023

AbstractNatural flood management (NFM), a nature‐based solution to flood mitigation where hydrological and biophysical processes are harnessed to reduce flow velocity, erosive energy and flood risk, is an emerging global theme of water and river management. The catastrophic 2021 and 2022 floods in eastern Australia are used to assess the hydrological properties of discrete events and to start an investigation of whether widespread changes in flood hydrology are occurring. We find that most coastal rivers in New South Wales (NSW) had a noticeable decrease in flood wave celerity (increase in flood travel time) when the 2021 and 2022 floods are contrasted with equivalent floods since the 1970s and that several also exhibit increases in flood peak attenuation. For some rivers, there is a coincident trend between these changing flood properties, riparian vegetation regrowth (regreening) and geomorphic recovery over the last +30 years. These may be the first signals that passive riparian management is counteracting some of the more severe hydrological effects of floods on these rivers and that some degree of NFM is possible. Lessons from this work are that there is an immediate opportunity to implement large‐scale NFM in coastal catchments of NSW, but this will only occur if we re‐examine current flood mitigation and adaption strategies and recognise and prioritise nature‐based solutions that include space‐to‐flood and corridors of river recovery, as essential parts of the modern flood mitigation toolkit.
Adherence to recommendations for nutrient supplementation related to pregnancy in Germany
Authors: Doru Berin , Hockamp Nele , Sievers Erika , Hülk Philipp , Lücke Thomas , Kersting Mathilde 
Published: June 2023

AbstractSupplementation of certain micronutrients is recommended to ensure their adequate supply during pregnancy and lactation. In Germany, this applies particularly to folic acid and iodine. There is no nationwide data on adherence to the supplementation guidelines. The aim of this cross‐sectional study was to determine the prevalence and predictors of the recommended supplementation of both folic acid and iodine in mothers of a nationwide birth cohort. Data on supplementation, before, during, and shortly after pregnancy, were collected retrospectively 14 days postpartum in a sample of 962 mother–infant pairs participating in the second nationwide study on breastfeeding and infant nutrition in Germany, called “SuSe II” (2017–2019). Folic acid and iodine supplementation were classified as recommended according to the German guidelines if supplementation was provided for both essential periods: for folic acid before and during pregnancy and for iodine during pregnancy and lactation. Univariable tests and multivariable logistic regression analysis were performed. The vast majority of mothers did not adhere to the recommendations, with only 36.2% supplementing folic acid and 31.9% supplementing iodine during the recommended periods, and only 15.2% adhering to the recommendations for both nutrients. Main predictors of adherence to recommendations of both nutrients were lifestyle attributes and nutrition‐related intentions like previous breastfeeding experience and breastfeeding intentions, but not common sociodemographic characteristics. The data suggest widespread dissemination of the time‐specific recommendations covering the entire period from preconception to lactation that could help to sensitize women and healthcare providers.
Altered habenular connectivity in chronic low back pain: An fMRI and machine learning study
Authors: Mao Cui Ping , Wu Yue , Yang Hua Juan , Qin Jie , Song Qi Chun , Zhang Bo , Zhou Xiao Qian , Zhang Liang , Sun Hong Hong 
Published: June 2023

AbstractThe habenula has been implicated in the pathogenesis of pain and analgesia, while evidence concerning its function in chronic low back pain (cLBP) is sparse. This study aims to investigate the resting‐state functional connectivity (rsFC) and effective connectivity of the habenula in 52 patients with cLBP and 52 healthy controls (HCs) and assess the feasibility of distinguishing cLBP from HCs based on connectivity by machine learning methods. Our results indicated significantly enhanced rsFC of the habenula‐left superior frontal cortex (SFC), habenula‐right thalamus, and habenula‐bilateral insular pathways as well as decreased rsFC of the habenula‐pons pathway in cLBP patients compared to HCs. Dynamic causal modelling revealed significantly enhanced effective connectivity from the right thalamus to right habenula in cLBP patients compared with HCs. RsFC of the habenula‐SFC was positively correlated with pain intensities and Hamilton Depression scores in the cLBP group. RsFC of the habenula‐right insula was negatively correlated with pain duration in the cLBP group. Additionally, the combination of the rsFC of the habenula‐SFC, habenula‐thalamus, and habenula‐pons pathways could reliably distinguish cLBP patients from HCs with an accuracy of 75.9% by support vector machine, which was validated in an independent cohort (N = 68, accuracy = 68.8%, p = .001). Linear regression and random forest could also distinguish cLBP and HCs in the independent cohort (accuracy = 73.9 and 55.9%, respectively). Overall, these findings provide evidence that cLBP may be associated with abnormal rsFC and effective connectivity of the habenula, and highlight the promise of machine learning in chronic pain discrimination.
Measuring quality of life at work for healthcare and social services workers: A systematic review of available instruments
Authors: Wang Liang , Touré Moustapha , Poder Thomas G. 
Published: June 2023

AbstractQuality of life at work is an important and widely discussed concept in the literature. Several instruments can be used to measure it, but with regard to healthcare and social services, the existing instruments are not well known. A review of available instruments intending to capture the quality of life of healthcare and social services workers (QoLHSSW) is necessary to better assess their working conditions and promote programs/guidelines to improve these conditions. The aim of this study was to identify the existing instruments used in measuring QoLHSSW and explore their characteristics. Particular attention was given to instruments adapted to the province of Quebec, Canada, which enabled the determination of which instruments are adapted for the measurement of QoLHSSW in Quebec and possibly elsewhere. A systematic review of the literature was conducted according to the JBI methodological guide. The articles' selection procedure was performed according to the PRISMA flowchart. The search was conducted up to October 28, 2021, and then updated on January 25, 2023, in four databases: PsycINFO, Medline, Embase, and CINAHL. The selection and extraction were performed independently by two researchers. The analysis of the quality of the studies was performed with the COnsensus‐based Standards for the selection of health Measurement Instruments. From a total of 8178 entries, 13 articles corresponding to 13 instruments were selected. Among these instruments, the common aspects that were considered were work conditions, job satisfaction, stress at work, relationship/balance, and career development. Most instruments used a 5‐point Likert scale. Various validation methods were used, including reporting Cronbach's alpha for overall scale reliability; factor analysis to test construct validity; different model fit indices to test model superiority; different language comparisons to test cross‐cultural validity; and qualitative expert reviews to assess content validity.
Post‐treatment 18F‐fludeoxyglocuse‐positron emission tomography in human papillomavirus‐associated oropharyngeal cancer
Authors: Liu Zhen Yu , Khoo Denver , Hartel Gunter , Punyadeera Chamindie , Vasani Sarju 
Published: June 2023

AbstractBackgroundHuman papillomavirus association has changed the landscape of treatment for oropharyngeal squamous cell carcinoma; it remains to be seen whether current post‐treatment surveillance schedules are effective.ObjectiveEvaluate whether post‐treatment surveillance of oropharyngeal cancer through FDG‐PET imaging is modified by human papillomavirus association.MethodsA prospective cohort analysis of retrospective data was conducted for patients undergoing treatment of oropharyngeal cancer between 2016 and 2018. This study was conducted at a single large tertiary referral center in Brisbane, Australia.ResultsTwo‐hundred and twenty‐four patients were recruited for the purposes of the study, 193 (86%) with HPV‐associated disease. In this cohort FDG‐PET had a sensitivity of 48.3%, specificity of 72.6%, positive predictive value of 23.7%, and negative predictive value of 88.8% in detecting disease recurrence.ConclusionsFDG‐PET in HPV‐associated oropharyngeal cancer has significantly lower positive predictive value when compared to non‐HPV‐associated oropharyngeal cancer. Caution should be used when interpreting positive post‐treatment FDG‐PET.
The difficulties in emotion regulation scale: Dimensionality, measurement invariance, and physiological correlates in community adolescents
Authors: Sousa Rúben , Linharelhos Mariana , Silva Diana Ribeiro da , Rijo Daniel 
Published: June 2023

AbstractObjectiveEmotion regulation is a central construct for the study of mental health in adolescence. Although the Difficulties in Emotion Regulation Scale (DERS) has been vastly used, several issues remain unanswered (e.g., factor structure/dimensionality). This study aimed to validate the 36‐items DERS in a sample of 989 Portuguese community adolescent (460 boys; 529 girls; age ranged from 14 to 18).MethodA bifactor‐ESEM model, comprising a general and six specific factors (nonacceptance; goals; impulses; strategies; clarity; awareness) was explored and considered the best fitting model.ResultsGender measurement invariance was established. When compared with boys, although differences were small in magnitude, girls presented higher emotion regulation difficulties. Evidence for reliability and construct/temporal validity were found, and significant associations between the DERS and physiological measures of emotion regulation (i.e., Heart Rate and Heart Rate Variability) were established.ConclusionFindings support the use of the DERS in adolescent samples.
Stand‐alone model for delivery of oral HIV pre‐exposure prophylaxis in Kenya: a single‐arm, prospective pilot evaluation
Authors: Ortblad Katrina F. , Mogere Peter , Omollo Victor , Kuo Alexandra P. , Asewe Magdaline , Gakuo Stephen , Roche Stephanie , Mugambi Mary , Mugambi Melissa Latigo , Stergachis Andy , Odoyo Josephine , Bukusi Elizabeth A. , Ngure Kenneth , Baeten Jared M. 
Published: June 2023

AbstractIntroductionThe delivery of daily, oral HIV pre‐exposure prophylaxis (PrEP) at private pharmacies may overcome barriers to PrEP delivery at public healthcare facilities, including HIV‐associated stigma, long wait times and overcrowding.MethodsAt five private, community‐based pharmacies in Kenya, a care pathway for PrEP delivery (ClinicalTrials.gov: NCT04558554) was piloted—the first of its kind in Africa. Pharmacy providers screened clients interested in PrEP for HIV risk, then used a prescribing checklist to identify clients without medical conditions that might contraindicate PrEP safety, counsel them on PrEP use and safety, conduct provider‐assisted HIV self‐testing and dispense PrEP. For complex clinical cases, a remote clinician was available for consultation. Clients who did not meet the checklist criteria were referred to public facilities for free services delivered by clinicians. Pharmacy providers dispensed a 1‐month PrEP supply at initiation and a 3‐month supply thereafter at a client fee of 300 KES (∼$3 USD) per visit.ResultsFrom November 2020 to October 2021, pharmacy providers screened 575 clients, identified 476 who met the prescribing checklist criteria and initiated 287 (60%) on PrEP. Among pharmacy PrEP clients, the median age was 26 years (IQR 22–33) and 57% (163/287) were male. The prevalence of behaviours associated with HIV risk among clients was high; 84% (240/287) reported sexual partners with unknown HIV status and 53% (151/287) reported multiple sexual partners (past 6 months). PrEP continuation among clients was 53% (153/287) at 1 month, 36% (103/287) at 4 months and 21% (51/242) at 7 months. During the pilot observation period, 21% (61/287) of clients stopped and restarted PrEP and overall pill coverage was 40% (IQR 10%–70%). Nearly, all pharmacy PrEP clients (≥96%) agreed or strongly agreed with statements regarding the acceptability and appropriateness of pharmacy‐delivered PrEP services.ConclusionsFindings from this pilot suggest that populations at HIV risk frequently visit private pharmacies and PrEP initiation and continuation at pharmacies is similar to or exceeds that at public healthcare facilities. Private pharmacy‐based PrEP delivery, conducted entirely by private‐sector pharmacy staff, is a promising new delivery model that has the potential to expand PrEP reach in Kenya and similar settings.
Shifting responses of phytoplankton to atmospheric and oceanic forcing in a prolonged marine heatwave
Authors: Zhan Weikang , Zhang Ying , He Qingyou , Zhan Haigang 
Published: June 2023

AbstractMarine heatwaves are becoming a severe challenge for marine ecosystems. However, current understanding of their impacts on phytoplankton, especially biomass and community structure, is still deficient or fragmentary. Here, we focus on the response of phytoplankton to a prolonged (372 d) marine heatwave in the southeastern tropical Indian Ocean in 2015–2016. Despite a similar surface warming throughout the marine heatwave, we found two distinctively different changes in chlorophyll a (Chl a) concentration, based on which the marine heatwave was divided into two phases of nearly equal duration. During Phase 1, the Chl a concentration and phytoplankton biomass increased slightly, while during Phase 2 they decreased dramatically, with a marked shift in phytoplankton community toward smaller‐size species. This difference mainly resulted from the change in dominant drivers of the marine heatwave, which shifted from atmospheric forcing (enhanced net air–sea heat flux) in Phase 1 to oceanic process (downwelling Kelvin waves) in Phase 2. The intensified near‐surface stratification and upwelling Kelvin waves led to a slight surface nutrient increase in Phase 1, while the downwelling Kelvin waves suppressed the seasonal upwelling in Phase 2, resulting in a substantial decrease in nutrient supply from the subsurface ocean, and hence dramatic decreases in Chl a concentration and biomass. Our results demonstrate the complex responses of phytoplankton to marine heatwaves and highlight the importance of distinguishing the driving mechanisms of marine heatwaves when evaluating their ecological impacts.
Quantitative and qualitative comparison of marine dissolved organic nitrogen recovery using solid phase extraction
Authors: Miranda Carlos , Boiteau Rene M. , McKenna Amy M. , Knapp Angela N. 
Published: June 2023

AbstractMarine dissolved organic carbon and nitrogen (DOC and DON) are major global carbon and nutrient reservoirs, and their characterization relies on extraction methods for preconcentration and salt removal. Existing methods optimize for capturing and describing DOC. Here, we report an optimized analytical strategy to recover marine DON for subsequent molecular characterization. Retention efficiencies between 5% and 95% are reported for seven solid phase extraction (SPE) sorbents, with PPL recovering 23% of marine DON compared to 95% recovered with C18. Additional comparisons of the effect of varying sample volumes and elution speed, and the resulting molecular composition of DON extracts, were investigated using C18 and PPL sorbents. Sample volumes > 200 mL decreased DON retention efficiency independent of SPE sorbent, and gravity elution recovered 1.7‐ to 4.2‐fold more DON compared to vacuum elution. Characterization of extracted DON by negative‐ion electrospray ionization Fourier transform‐ion cyclotron resonance mass spectrometry (FT‐ICR MS) highlights compositional differences between DON species recovered by each method. DON isolated with optimized methods includes low molecular weight (< 600 Da) peptide‐like compounds with low O:C ratios (0.2 to 0.5) that are not detected by other SPE sorbents (e.g., PPL). The majority of additional DON isolated with this approach was undetectable by direct infusion negative mode FT‐ICR MS analysis.
On singular generalizations of the Singer–Hopf conjecture
Authors: Maxim Laurenţiu 
Published: June 2023

AbstractThe Singer–Hopf conjecture predicts the sign of the topological Euler characteristic of a closed aspherical manifold. In this note, we propose singular generalizations of the Singer–Hopf conjecture, formulated in terms of the Euler–Mather characteristic, intersection homology Euler characteristic and, resp., virtual Euler characteristic of a closed irreducible subvariety of an aspherical complex projective manifold. We prove these new conjectures under the assumption that the cotangent bundle of the ambient variety is numerically effective (nef), or, more generally, when the ambient manifold admits a finite morphism to a complex projective manifold with a nef cotangent bundle. The main ingredients in the proof are the semi‐positivity properties of nef vector bundles together with a topological version of the Riemann–Roch theorem, proved by Kashiwara.
Initiator‐Free Photocuring 3D‐Printable PVA‐Based Hydrogel with Tunable Mechanical Properties and Cell Compatibility
Authors: Li Chao , Lu Guoqiang , Wang Guohua , Liu Bo , Xue Tanlong , Yuan Hengda , Nie Jun , Zhu Xiaoqun 
Published: June 2023

AbstractPoly(vinyl alcohol) (PVA)‐based hydrogels have attracted great attention and been widely used in biological tissue engineering. With the development of modern medicine, precision medicine requires the customization of medical materials. However, lacking of photocurable functional groups or the performance of rapid phase transition makes PVA‐based hydrogels difficult to be customizable molded through photocuring 3D printing technique. In this research, customizable PVA‐based hydrogels with high performance through 3D photocurable printing and freezing‐thawing (F‐T) process are obtained. The ability of 3D‐printable is endowed by the introduction of polyvinyl alcohol–styrylpyridine (PVA‐SBQ), which can be photo‐crosslinked quickly without photoinitiator. Meanwhile, the tunable mechanical properties are achieved by adjusting the mass ratio of PVA‐SBQ to PVA, and PVA can offer the physical crosslinking points through freezing‐thawing (F‐T) process. The hydrogels with high resolution are prepared by digital light procession 3D printing with the mass ratio 1:1 of PVA‐SBQ to PVA solution. Attributed to the absence of initiator, and no small molecule residues inside the hydrogels, the hydrogels have good biocompatibility and have the potential to be applicated in the field of biological tissue engineering.
Sperm capacitation as a predictor of boar fertility
Authors: Keller Alexandra , Kerns Karl 
Published: June 2023

AbstractPrediction of a boar's fertility level has great economic importance for sow herds. After standard sperm morphology and motility metrics are met, approximately 25% of boars have less than 80% conception rates. Due in part to the many factors involved in the fertilization process, a multifactorial model incorporating multiple relevant sperm physiology factors will likely lead to increased understanding of boar fertility. Here we review the current literature on boar sperm capacitation as a predictor of boar fertility. While limited, several studies have provided correlations between the percentage of sperm in an ejaculate that are capable of undergoing sperm capacitation in a chemically defined media and artificial insemination field fertility as well as proteome and other methods. Work summarized here underscores the need for further understanding of boar fertility.
A local spectrum enhancement‐based method and its application in incipient fault diagnosis of rotating machinery
Authors: Shi Jiancong , Xu Baoming , Wang Xinglong , Zhang Jun 
Published: June 2023

AbstractIncipient faults of gears and rolling bearings in rotating machineries are very difficult to identify using traditional envelope analysis methods. To address this challenge, this paper proposes an effective local spectrum enhancement‐based diagnostic method that can identify weak fault frequencies in the original complicated raw signals. For this purpose, a traversal frequency band segmentation technique is first proposed for dividing the raw signal into a series of subfrequency bands. Then, the proposed synthetic quantitative index is constructed for selecting the most informative local frequency band (ILFB) containing fault features from the divided subfrequency bands. Furthermore, an improved grasshopper optimization algorithm‐based stochastic resonance (SR) system is developed for enhancing weak fault features contained in the selected most ILFB with less computation cost. Finally, the enhanced weak fault frequencies are extracted from the output of the SR system using a common spectrum analysis. Two experiments on a laboratory planetary gearbox and an open bearing data set are used to verify the effectuality of the proposed method. The diagnostic results demonstrate that the proposed method can identify incipient faults of gears and bearings in an effective and accurate manner. Furthermore, the advantages of the proposed method are highlighted by comparison with other methods.