bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased levels of a subset of angiogenesis-related plasma proteins in essential thrombocythemia
Authors: Vikman Sofia , Larsson Anders , Thulin Måns , Karlsson Torbjörn 
Published: March 2023

Background: Increased local angiogenesis is important for the growth and dissemination of cancer. The myeloproliferative neoplasm essential thrombocythemia (ET) is known to involve increased bone marrow angiogenesis. Blood levels of several angiogenesis-related proteins are increased in different types of cancer. The aim of this study was to investigate whether a subset of such proteins was elevated in treatment-naïve ET patients.
Methods: Blood plasma from 41 ET patients and 43 healthy aged-matched controls was analyzed for eight different angiogenesis-related proteins.
Results: The ET cohort displayed a more homogenous expression pattern of these proteins compared with controls. Five of the eight proteins were significantly increased in ET patients.
Conclusion: Increased plasma levels of matrix metallopeptidase 9 (MMP9) and endostatin have not previously been reported in ET. In our patients, MMP9 levels correlated positively with Janus kinase 2 (JAK2) V617F allele burden and leukocyte count.
Nos rastros da opressão: manifestações da violência em Triste fim de Policarpo Quaresma, de Lima Barreto
Authors: Da Silva Luiz Felipe Verçosa 
Published: March 2023

O presente trabalho tem por objetivo explanar sobre o contexto histórico do Brasil na época do carioca Lima Barreto. Com foco no período entre o fim do século XIX e o início do século XX, época que coincide com a criação do romance Triste Fim de Policarpo Quaresma (1915). Será abordada nesta pesquisa a constituição da Literatura de Lima Barreto e os conceitos filosóficos de Violência, sendo posteriormente feita uma análise do livro sobre a manifestação dos traços de violência presentes na obra, estudados pelo viés do filósofo-psicanalista esloveno Slavoj Žižek, o qual defende a ideia de que existem dois tipos de violência: a subjetiva, que é vista e reconhecida como tal e a invisível, que é entendida como a violência que ocorre de forma despercebida, porém, que também é constitutiva de toda forma de violência subjetiva. Diante desta perspectiva, este trabalho ambiciona investigar a forma como se estrutura as marcas das violências visíveis e invisíveis na narrativa do romance. Para a constituição dessa pesquisa, tornou-se necessário um levantamento bibliográfico, utilizado como base para a fundamentação teórica, contando das obras de ŽIŽEK (2006, 2010, 2014), ARENDT (1985), que pensa a violência a partir das relações de poder e WEIL (2013), com o seu pensamento filosófico sobre a gênese das ações violentas.
Palavras-chave: Violência; Literatura Brasileira; Triste Fim de Policarpo Quaresma; Lima Barreto.
A importância do estágio curricular supervisionado para a formação docente: relato de uma vivência na EJAI
Authors: Gonzaga Maria Dayane Martins 
Published: March 2023

RESUMO: O respectivo relato é resultado das ações e vivências que foram perpassadas ao longo do Estágio Curricular Supervisionado na Educação de Jovens, Adultos e Idosos (EJAI), no semestre letivo de 2022.1. Este, tem por objetivo, trazer à tona algumas reflexões acerca da importância do Estágio Curricular Supervisionado para a formação docente, bem como acerca de como se deu o processo de inserção na escola campo e os desafios vivenciados na prática docente enquanto professora da Educação de Jovens, Adultos e Idosos. A metodologia abordada corresponde a um desdobramento da Pesquisa-ação e foram utilizados como procedimentos as vivências suscitadas a partir das ações desenvolvidas. Para dialogar com as temáticas propostas, fez-se uso dos estudos das autoras Hugues (2007), Pimenta e Lima (2017), Ostetto (2008). Para auferir, o referido relato evidencia a pertinência do Estágio Curricular Supervisionado para a formação dos licenciandos e ressalta algumas situações desafiadoras que foram experienciadas ao longo das práticas em sala de aula.
Palavras-chave: Estágio Curricular Supervisionado. Formação docente. Vivência.

ABSTRACT: The respective report is the result of actions and experiences that were permeated throughout the Supervised Curricular Internship in Youth, Adult and Elderly Education (EJAI), in the academic semester of 2022.1. This aims to bring up some reflections about the importance of the Supervised Curricular Internship for teacher training, as well as about how the process of insertion in the field school took place and the challenges experienced in teaching practice as a teacher of Youth Education, Adults and Seniors. The approached methodology corresponds to an unfolding of the Action-Research and the experiences raised from the developed actions were used as procedures. To dialogue with the proposed themes, studies by authors Hugues (2007), Pimenta e Lima (2017), Ostetto (2008) were used. In order to earn, the aforementioned report highlights the pertinence of the Supervised Curricular Internship for the training of undergraduates and highlights some challenging situations that were experienced throughout the practices in the classroom.
Keywords: Supervised internship. Teacher training. Experience.
Geografizando a diversidade cultural: o Estágio Supervisionado na Educação de Jovens, Adultos e Idosos
Authors: Almeida Ricardo Santos de 
Published: March 2023

RESUMO: Este artigo tem por objetivo problematizar experiências didático-pedagógicas aprendidas colaborativamente no âmbito da Geografia em turma da Educação de Jovens, Adultos e Idosos no município Pariconha/AL, no ano de 2017. Neste relato de experiência, analisaremos do espaço escolar às suas múltiplas dimensões de uso e ocupação geográficos pela comunidade escolar oportunizados pelo componente curricular Estágio Supervisionado Docência na EJA e Normal da Unidade Temática de Aprendizagem Metodologias da Linguagem e História do curso Pedagogia Licenciatura, do Centro Universitário UNINTER. Para o desenvolvimento da análise foram realizadas discussões envolvendo a compreensão do espaço escolar a partir de Pimenta e Lima (2004), Veiga (2001), dentre outros, e a educação geográfica a partir de Moreira (2008), Santos (2012) dentre outros, confluindo pela experiência do estágio supervisionado em Geografia a busca pelo ser mais a partir de Freire (2010).

Palavras-chave: Ensino-aprendizado. Geografia. Ser mais.

ABSTRACT: This article aims to problematize didactic-pedagogical experiences learned collaboratively within the scope of Geography in a class of Educação de Jovens, Adultos e Idosos in the municipality of Pariconha/AL, in the year 2017. In this experience report, we will analyze the school space to its multiple dimensions of geographic use and occupation by the school community made possible by the curricular component Estágio Supervisionado Docência na EJA e Normal of the Unidade Temática de Aprendizagem Metodologias da Linguagem e História of the Pedagogia Licenciatura course, of the University Center UNINTER. For the development of the analysis, discussions were carried out involving the understanding of the school space from Pimenta e Lima (2004), Veiga (2001), among others, and geographic education from Moreira (2008), Santos (2012) among others, converging on the experience of the supervised internship in Geography with the search for being more from Freire (2010).
Keywords: Teaching-learning. Geography. Be more.
Neofascismo brasileiro e suas articulações transnacionais: uma contribuição a partir das Relações Internacionais
Authors: Magalhães David 
Published: March 2023

Este artigo consiste em um diálogo com o Odilon Caldeira Neto, com base no artigo de sua autoria “O Neofascismo no Brasil, local ou global?”, publicado na seção debate da revista Esboços. Duas reflexões são propostas neste breve comentário: primeiramente, procuro inserir as organizações de extrema direita brasileira dentro de um quadro mais amplo e complexo de transnacionalização que se opera no Sistema Internacional com a intensificação da globalização, valendo-me de uma literatura no campo das Relações Internacionais; (ii) No contexto do surgimento da nova direita brasileira, problematizo o enquadramento de alguns atores como neofascistas, dada a estratégia de metapolitização adotada por diversas organizações ultradireitistas no Brasil.
MELALUI SUPERVISI MANAJERIAL DAPAT MENINGKATKAN KINERJA KEPALA SEKOLAH DALAM MENYUSUN RENCANA KERJA TAHUNAN
Authors: SUMARNI BAIQ 
Published: March 2023

This study aims to determine the increase in annual performance based on school unit report cards carried out by school principals through managerial supervision at target schools in West Lombok Regency. This research is an action research head of supervision or PTKp. The subjects in this study were the principals of public and private schools in West Lombok Regency who were supervised by supervisors (researchers) for the 2022-2023 school year. Based on the analysis of the results of the research and discussion, it can be concluded that supervising supervisors through effective managerial supervision can improve the performance of school principals in preparing RKTs based on school unit reports in the 2022-2023 school year in the assisted junior high schools of West Lombok Regency. This can be seen by the increase in the results of the questionnaire for each cycle, namely cycle I 56%, cycle II 76% and cycle III 88%. Not only that, this can be seen with the predicted value in the first cycle of 2.8 (almost enough), the second cycle is 3.8 (almost good) and the third cycle is 4.4 (good).
ABSTRAKPenelitian ini bertujuan untuk mengetahui peningkatan kinerja kepala sekolah dalam menyusun rencana kerja tahunan berdasarkan rapor satuan pendidikan yang dilakukan oleh pengwas sekolah melalui supervisi manajarial pada sekolah binaan di Kab Lombok Barat. Penelitian ini merupakan penelitian tindakan kepengawasan atau PTKp. Subyek dalam penelitian ini adalah Kepala sekolah Negeri dan Swasta di Kabupaten Lombok Barat yang menjadi Binaan Pengawas (Peneliti) tahun pelajaran 2022-2023. Berdasarkan analisis hasil penelitian dan diskusi dapat disimpulkan bahwa pembinaan pengawas melalui supervisi manajerial efektif dapat meningkatkan kinerja kepala sekolah dalam menyusun RKT berdasarkan rapor satuan pendidikan pada tahun pelajaran 2022-2023 di SMP binaan Kabupaten Lombok Barat. Hal ini dapat dilihat dengan meningkatnya hasil angket tiap-tiap siklus yaitu siklus I 56%, siklus II 76% dan siklus III 88%. Tidak hanya itu hal tersebut dapat dilihat dengan nilai prediksi pada siklus pertama sebesar 2,8 (hampir cukup), siklus kedua 3,8 (hampir baik) dan siklus ketiga 4,4 (baik).
PENGARUH PERSEPSI TERHADAP KESIAPAN KERJA MELALUI KEPUASAN PRAKTEK KERJA LAPANGAN MAHASISWA PERGURUAN TINGGI VOKASI PARIWISATA
Authors: Priyanto Priyanto , Widiarto Setyo , Darmadi Roby , Rahayu Nurti 
Published: March 2023

On the Job Training (OJT) as part of the tourism vocational education curriculum is more than just a requirement to meet the adequacy of student graduation credits, OJT is required to provide student experience and competence to work after graduation. This study aims to determine work readiness which is determined by the perception and satisfaction of student OJT . This is a quantitative research utilizing the Structural Equation Model (SEM) as an analysis method. Utilizing the Work Readiness Scale (WRS) to quantify the level of student work readiness, the research results revealed that student perceptions did not significantly affect student OJT satisfaction, student OJT perception and satisfaction had a positive and significant effect on work readiness, while an indirect relationship between student perceptions of work readiness through OJT satisfaction showed insignificant results. These results conclude that factors that affect job satisfaction during the implementation of OJT have a significant impact on student work readiness. In the end, tourism vocational universities are required to be able to manage OJT well as an effort to create graduates who have competence and are ready to work and are highly competitive in the business world.
Pengaruh Model Pembelajaran Learning Contract (Kontrak Belajar) terhadap Hasil Belajar Peserta Didik Kelas XI IPS Madrasah Aliyah Nurul Islam Pungging Mojokerto
Authors: Fauzi Ahmad , Prasetyo Yudi , Christiawan Yuddy 
Published: March 2023

Artikel ini bertujuan mengetahui pengaruh penerapan learning contract terhadap pemahaman dan hasil belajar sejarah materi kolonialisme dan imperialisme di Indonesia peserta didik kelas XI IPS MA Nurul Islam Pungging Mojokerto. Artikel ini merupakan penelitian kuantitatif dengan desain eksperimen dengan pola pretest posttest design. Kelas XI IPS Lughoh sebagai kelas kontrol dan kelas XI IPS Alat sebagai kelas eksperimen yang diberi perlakuan dengan learning contract. Data hasil penelitian diperoleh sebagai berikut: Hasil validasi learning contract dari validator dengan nilai 5 dengan kategori sangat baik, validasi instrumen soal rata-rata nilai 5 dengan kategori sangat baik, validasi instrumen angket respon peserta didik rata-rata nilai 4 dengan kategori sangat baik. Uji hipotesis dengan taraf signifikansi (sig.2-tailed) adalah 0,000 lebih kecil dari 0,05 maka Ho ditolak dan H1 diterima dengan kriteria ada pengaruh yang signifikan penggunaan learning contract terhadap nilai sebelum (pretest) dan sesudah (posttest). Berdasarkan hasil penelitian, disimpulkan bahwa terdapat pengaruh yang signifikan penggunaan model pembelajaran learning contract terhadap hasil belajar peserta didik Kelas X MA Nurul Islam Pungging Kab. Mojokerto. Sehingga dapat membangun karakter peserta didik yang mandiri, jujur, percaya diri, karena peserta didik sebelum melaksanakan pembelajaran harus membuat kesepakatan belajar yang dikenal dengan istilah learning contract. Peserta didik lebih bersemangat dalam kegiatan pembelajaran karena memiliki target atau tujuan belajara yang jelas. Hal ini tercermin pada kelas XI IPS Alat sebagai kelas eksperimen dalam penelitian ini mendapat nilai yang lebih baik antara pre test dan post test melalui learning contract. Persepsi peserta didik yang mendapatkan pembelajaran dengan pemanfaatan model pembelajaran learning contract lebih termotivasi untuk meningkatkan prestasi hasil belajarnya. Hal tersebut dikarenakan sebelum pembelajaran berlangsung peserta didik dan pendidik telah membuat sebuah kesepakatan tertulis berupa learning contract sehingga peserta didik termotivasi untuk lebih giat belajar karena mereka berusaha untuk mencapai target-target hasil pembelajarannya yang akan dicapai sesuai dengan kesepakatan bersama guru mata pelajaran sejarah
STATE REGULATION OF THE REGIONAL AGRO-INDUSTRIAL COMPLEX ON THE PROJECT APPROACH
Authors: Мокрушин А.А. , Прохорова В.В. , Рычковская Д.Н. 
Published: March 2023

Статья посвящена изучению региональных аспектов государственного регулирования АПК региона на основе проектного подхода. Раскрыта роль программно-целевого планирования на принципах проектного управления в обеспечении социально-экономического развития территориального АПК. Раскрыты территориально-отраслевые особенности АПК Республики Адыгея, обусловливающие меры государственного регулирования хозяйственных процессов. Проведен анализ результатов реализации региональных проектов «Экспорт продукции АПК в Республике Адыгея» и «Создание системы поддержки фермеров и развитие сельской кооперации в Республике Адыгея», направленных на повышение конкурентоспособности агропромышленного производства в регионе депрессивного типа. Представлены стратегические направления модернизации АПК Республики Адыгея, действенные инструменты государственного регулирования воспроизводственных процессов. Раскрыты основные проблемы и направления развития проектного управления социально-экономическими процессами в АПК депрессивного региона
The article is devoted to the study of regional aspects of state regulation of the regional agro-industrial complex on the basis of project approach. The role of program-target planning based on the principles of project management in ensuring the socio-economic development of the territorial agro-industrial complex is revealed. The territorial and sectoral features of the agro-industrial complex of the Republic of Adygea, which determine the measures of state regulation of economic processes, are disclosed. The analysis of the results of the implementation of regional projects «Export of agricultural products in the Republicof Adygea» and «Creation of a system of support for farmers and development of rural cooperation in the Republic of Adygea» aimed at increasing the competitiveness of agro-industrial production in the depressed region. The strategic directions of modernization of the agro-industrial complex of the Republic of Adygea, effective instruments of state regulation of reproductive processes are presented. The main problems and directions of development of project management of socio-economic processes in the agro-industrial complex of the depressed region are revealed. Keywords: state regulation, socio-economic development, project approach, instruments, agro-industrial complex, Republic of Adygea, federal project, regional project, state programs, project management, strategic objectives.
Frequency of anemia in patients presenting with ulcerative colitis
Authors: Ullah Zabih , Shah Waqar , Hidayat Rania , Riaz Ummarah , Naseer Adil , Khan Hafizullah 
Published: March 2023

Introduction: Anemia appears to be the most common extra intestinal manifestation of inflammatory bowel disease and has been associated with a wide range of complications such as impaired quality of life, an increased rate of hospital admissions and even mortality. Objective: To determine the frequency of anemia in patients presenting with ulcerative colitis. Material and methods;This Cross Sectional Study was conducted in the Department of Gastroenterology, ATH, Abbottabad from 20th September 2020 to 20th March 2021. A total of 109 patients of both gender with ulcerative colitis were included in the study. Venous blood was collected from all patients in sodium EDTA tube by a 3rd year resident and was immediately sent to hospital laboratory. Hemoglobin < 11 g/dL was recorded as anemia and noted. Results: Age range in this study was from 18 to 60 years with mean age of 41.550±6.56 years, mean duration of complain was 9.862±2.57 months and mean weight was 80.091±7.60 Kg. Male patients were 63.3% and females were 36.7%. Anemia was observed in 14.7% Patients presenting with ulcerative colitis. Conclusion: In conclusion, we found a high incidence and prevalence of anaemia in patients presenting with ulcerative colitis.
The characteristics, convictions, and incidents of risk of women in the national high secure healthcare service for women
Authors: Clarke Martin , Williams Marie , Siddall Yasmin , Lewis Jessica 
Published: March 2023

PurposeA service evaluation was conducted to characterise all admissions to the National High Secure Healthcare Service for Women (NHSHSW).Design/methodology/approachData were obtained from computerised records, case notes, and the hospital’s Risk Department. Data collected included the date of incident, incident type, location of incident and name of aggressor. The severity of incidents were reported from 2010 onwards. Some data are presented in three time bands: 2007, 2008–2011, and 2013–2015 in order to illustrate changes. Some data is presented in three age bands based on age at admission: under 30 years old, 30–39 years old and 40 years and over.Findings105 women were admitted into the service between January 2007 and 30 June 2015. The majority of women had a diagnosis of personality disorder (81.0 per cent), a history of trauma (e.g. it was documented that 71.4 per cent had experienced sexual abuse) and had received a criminal conviction (90.5 per cent). A total of 8934 risk incidents were reported and the majority of women (N = 101, 96.2 per cent) were involved in at least one incident during their admission. The majority of recorded incidents involved self-harm (70.9 per cent).Originality/ValueLittle has been published about the NHSHSW population. This article outlines the characteristic profiles of women detained in high secure care.Practical implicationsThe complex background and clinical characteristics highlight the need for trauma-informed practice. Continuous monitoring is required to ensure effective practices.
Technology innovation to support young people in the children and young people secure estate
Authors: Lee Robyn , McKeown Annette , Brown Daniel , Conlon Aileen , Sutherland Perry , Moss Andrew , Mitchell Anthony , Kennedy Patrick J 
Published: March 2023

BackgroundThe use of technology within education and mental health provision has progressed significantly over recent years and opportunities for integrated provision to utilise technology to enhance young people’s learning and psychological wellbeing are on the rise. Access to education has been found to be a protective factor for young people in forensic populations, whereas a lack of engagement in education can be a risk factor for offending. The use of technology is also evolving within forensic settings and may support engagement in therapeutic interventions.ObjectiveThe current paper offers feedback from young people and staff within a Secure Children’s Home (SCH) in the North East of England, regarding their views on technology as a means to enhance learning and psychological wellbeing.MethodThe Meganexus Virtual Campus In-Room system is a viable solution for in-room technology with an emphasis on security and accessibility in secure settings. This system was demonstrated and reviewed by a total of eight young people and 35 staff members within a SCH. Preferences and views regarding the feasibility and efficacy of technology in young people’s secure services were examined.ResultsOverall, young people and staff felt that technology could be useful to support young people’s education and psychological wellbeing. Qualitative feedback highlighted several recommendations relating to education, multidisciplinary working, empowering young people, and promoting wellbeing. Conclusion: Promoting education and psychological wellbeing is essential within forensic settings for young people, and technology may provide an innovative solution to enhance engagement within secure settings. Implications and recommendations for future research are presented.
QUEM SÃO E COMO GASTAM OS CONSUMIDORES DA MICRORREGIÃO DE JAÚ-SP
Authors: Favoni Célio , Mendes Gerotti Franco Nathália 
Published: March 2023

Potencial de consumo reflete um limite superior para as transações que podem ocorrer numa determinada localização, quando são consideradas todas as unidades vendedoras e compradoras de uma categoria de bem ou serviço. Assim, estudos voltados para o tamanho do mercado consumidor são importantes, especialmente para identificar o perfil de gastos dos indivíduos de diferentes regiões e classes socioeconômicas. Diante do exposto, o objetivo deste artigo é quantificar o potencial de consumo, para o ano de 2019, dos municípios que compreende a microrregião de Jaú/SP. Trata-se de uma pesquisa quantitativa onde os dados foram extraídos de institutos governamentais e do Índice de Potencial de Consumo (IPC Maps). Para a definição de classes de rendimento foi adotado o Critério de Classificação Econômica Brasil. Os resultados indicaram que a microrregião possui mais de 389 mil habitantes, 96,6% vivem em área urbana e 60% são economicamente ativos (entre 15 e 60 anos). O Potencial de Consumo foi estimado em R$ 9,6 bi (2019), sendo que 66,9% estão concentrados nas cidades de Jaú (39,3%), Pederneiras (11,6%), Barra Bonita e Igaraçu do Tietê (16%). A maior parcela do consumo da população foi com habitação (27,48%), seguido por despesas com beleza, empregados, serviços (17,22%). A classe B foi a responsável pelo maior volume de gastos em produtos e serviços com 44,1% do total. A classe C produziu um gasto de mais de R$ 3,4 bi, o que representou 35,2% do total.
Palavras- chave: Potencial de Consumo. Classe Econômica. Microrregião de Jaú.