bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Reverse Fragility Index: Interpreting the Current Literature on Long-Term Survivorship of Computer-Navigated Versus Conventional TKA
Authors: Shi Jeffrey L. , Mojica Edward S. , Moverman Michael A. , Pagani Nicholas R. , Puzzitiello Richard N. , Menendez Mariano E. , Salzler Matthew J. , Gordon Matthew , Bono James V. 
Published: January 2023

Background:
Despite the most recent American Academy of Orthopaedic Surgeons clinical practice guideline making a “strong” recommendation against the use of intraoperative navigation in total knee arthroplasty (TKA), its use is increasing. We utilized the concept of the reverse fragility index (RFI) to assess the strength of neutrality of the randomized controlled trials (RCTs) comparing the long-term survivorship of computer-navigated and conventional TKA.

Methods:
A systematic review was performed including all RCTs through August 3, 2021, comparing the long-term outcomes of computer-navigated and conventional TKA. Randomized trials with mean follow-up of >8 years and survivorship with revision as the end point were included. The RFI quantifies the strength of a study’s neutrality by calculating the minimum number of events necessary to flip the result from nonsignificant to significant. The RFI at a threshold of p < 0.05 was calculated for each study reporting nonsignificant results. The reverse fragility quotient (RFQ) was calculated by dividing the RFI by the study sample size.

Results:
Ten clinical trials with 2,518 patients and 38 all-cause revisions were analyzed. All 10 studies reported nonsignificant results. The median RFI at the p < 0.05 threshold was 4, meaning that a median of 4 events would be needed to change the results from nonsignificant to significant. The median RFQ was 0.029, indicating that the nonsignificance of the results was contingent on only 2.9 events per 100 participants. The median loss to follow-up was 27 patients. In all studies, the number of patients lost to follow-up was greater than the RFI.

Conclusions:
The equipoise in long-term survivorship between computer-navigated and conventional TKA rests on fragile studies, as their statistical nonsignificance could be reversed by changing the outcome status of only a handful of patients––a number that was always smaller than the number lost to follow-up. Routine reporting of the RFI in trials with nonsignificant findings may provide readers with a measure of confidence in the neutrality of the results.

Level of Evidence:
Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
LA ARQUITECTURA TRADICIONAL CHILENA: DE SU DESCUBRIMIENTO POR LA ACADEMIA A SU PUESTA EN VALOR TURÍSTICO-CULTURAL. ESTUDIOS DE CASOS
Authors: Valenzuela Blossin Maria Paz 
Published: January 2023

ResumenLa valorización del patrimonio arquitectónico en Chile se sustenta desde sus inicios en la investigación académica. En este ámbito tuvieron un papel relevante los llamados arquitectos historiadores, profesionales que centraron sus estudios y su quehacer en la puesta en valor de las expresiones tradicionales y docta de la arquitectura en Chile, desde la particular mirada de la disciplina arquitectónica. Esta vocación dio visibilidad a expresiones vernáculas muy propias de diversas regiones del país, las que reflejan la particular condición geográfica del medio en que se desarrollan, legando una protección y reconocimiento nacional que ha seguido avanzando en el tiempo. Muchos de estos casos hoy son reconocidos y valorados por las comunidades locales y sus propietarios proyectándose en interesantes ejemplos de actividad productiva, esta vez desde el ámbito del turismo. En consecuencia, este artículo busca presentar como una expresión arquitectónica descubierta y puesta en valor desde la Academia -la arquitectura tradicional, concluyéndose que puede persistir y sustentarse basándose en la adaptación a nuevos usos, esta vez turísticos, que permiten su subsistencia desde la gestión empresarial.Palabras clave:Arquitectura tradicional chilena, uso turístico del patrimonio, Chiloé, Estancias Magallánicas, Casas Patronales del Valle Central. AbstractThe valorization of the architectural heritage in Chile, is sustained from its beginnings in academic research, in this area a relevant role has been the so-called architects historians, professionals who have focused their studies and their work in the enhancement of traditional expressions and learned architecture in Chile, from the particular view of the architectural discipline. This vocation gave visibility to vernacular expressions very typical of different regions of the country, which reflect the particular geographical condition of the environment in which they are developed, bequeathing a national protection and recognition that has continued to advance over time, many of these cases are now recognized and valued by the communities and their owners projecting themselves in interesting examples of productive activity, this time from tourism. Consequently, this article seeks to present an architectural expression discovered and valued from academia, traditional architecture, whose persistence and sustainability is based on adapting to new uses, this time tourism, which allow their subsistence based on business management.Key words:Traditional Chilean Architecture, tourism and heritage, Chiloé, Magellanic stations, Central Valley Patron Houses.
Spontaneous-figurative Memory in the Works of Henri Bergson and in Sufism (Comparative Analysis)
Authors:   National University of Uzbekistan named after Mirzo Ulugbek, Kabulniyazova Gulchehra T. 
Published: January 2023

In his work Matter and Memory, Henri Bergson asserts the existence of two forms of memory: mechanical, based on repetition and spontaneous-figurative, in which the activity of the spirit manifests itself. Similar thoughts about the con­nection of figurative memory with the activity of the spirit were expressed at one time by the Central Asian outstanding thinker, founder of the Sufi Tariqa Najm ad-Din Kubra and the famous Persian mystic poet Jalal ad-Din Rumi. According to Kubra, spontaneous-figurative memory is located in the depths of a person’s spiritual heart and the path to it is reached through various spiritual states that have different colors for inner vision, these colors symbolize the levels of spiri­tual development and are called in Kubra’s teaching by the word “latoif”. At the highest stage of spiritual development, a treasure trove of memory opens for the seeker. It stores not just beautiful images that were a source of inspiration for po­ets, but this memory has a huge psychic power with which the spirit manifests its active activity. He materializes these images, thanks to the spontaneous-figura­tive memory, the connection of matter and spirit occurs. Spiritual love and intu­ition help the seeker to go through various stages of spiritual evolution and reach the treasury of spontaneous-imaginative memory.
Case Study: Predicting Electrical Submersible Pump Failures Using Artificial Intelligence and Physics-Based Hybrid Models
Authors: Silvia Shejuti , Gilad Yocheved , Wilson Thomas Andrew , Akbari Babak , Furlong Edward R. 
Published: January 2023

Abstract
Despite being the most widely used artificial lift method for high-producing oil wells, ESPs still experience unplanned failures that impact well productivity and overall field economics. Our advanced ESP Predictive Failure Analytics (PFA) can help detect ESP events ahead of time and extend the overall ESP run life. PFA enabled a major Latin American operator, experiencing frequent unplanned ESP failures, to identify critical events while pumps were running and take remedial actions to extend ESPs run life.

Methods, Procedures, Process
PFA leverages artificial intelligence (AI), statistical and physics-based models to reliably predict Remaining Useful Life (RUL) and possible failure cause. The models are trained using historical sensor time-series from both running and failed ESPs. The trained models are deployed to predict short-term events that may lead to immediate failure, such as a broken shaft, short-circuit, grounded downhole failure; as well as long-term events which build up over time, such as pump low efficiency, sand, scale deposition and gassy conditions.

Results, Observations, Conclusions
For this study, we used two ESPs. For ESP-1, PFA predicted broken shaft/missed pump stages after a sudden decline in motor current and production rate. As the production rate declined beyond the minimum recommended operating range, PFA identified downthrust condition and estimated a significant RUL reduction. PFA enables the operator to quickly schedule a workover, reducing downtime. For ESP-2, intake pressure and motor current started decreasing and motor temperature started increasing. PFA predicted sand influx and estimated a significant RUL reduction. A chemical injection was applied to reduce sand, and avoid an imminent failure leading to PFA estimating an increased RUL.

Novel/Additive Information
PFA is an innovative approach which combines AI, statistical and physics-based methods to provide explainable predictions of ESP failure. Unlike commonly used threshold-based approaches, PFA tends to generate fewer alarms which enables proactive optimization of ESP performance, avoiding unplanned failures and extend ESP run life.
Inflammatory Myofibroblastic Tumour of the Common Bile Duct: A Case Report and Literature Review
Authors: Huang Xiang , Li Guoli , Wang Jinjing , Zheng Hong 
Published: January 2023

Abstract
Introduction: Inflammatory myofibroblastic tumour of the common bile duct (CBD) is an extremely rare low-grade malignancy with various biological behaviours and a lack of specific clinical and histopathological features. Preoperative and intraoperative diagnosis are challenging, and an undiagnosed tumour can cause increased surgical trauma. Case presentation: We report a 34-year-old male who presented with yellowish whole-body skin and yellowish eyes for 20 + days. There was no history of abdominal swelling or pain, fever or chills. Computed tomography (CT) revealed a well-defined, asymmetrical, circumferential obstructing mass in the hilum-mid CBD. The patient was suspected to have cholangiocarcinoma and underwent total bile duct tumour resection and digestive tract reconstruction. The postoperative pathological diagnosis was inflammatory myofibroblastic tumour, and the patient was followed up for three years and exhibited good health. Conclusion: We report a case and literature review regarding inflammatory myofibroblastic tumour of the CBD, which is an extremely rare low-grade malignancy.
Improving the Value and Efficiency of Healthcare Services by Integrated Data Envelopment Analysis and Organizational Structure Design
Authors: Barros Oscar , Diaz Jorge 
Published: January 2023

Abstract
Measuring the efficiency of health services using Data Envelopment Analysis is a common practice nowadays. In addition, some studies use analytical techniques to discover the variables that explain the efficiency level of such services. Nevertheless, few efficiency analyses have resulted in proposals to design organizational health care structures that provide adequate management for actually improving efficiency. Thus, to address the lack of use of Data Envelopment Analysis results in practice, this paper provides a general methodology based on the idea that measuring the efficiency of healthcare services must be complemented with their redesign to obtain potential efficiency improvements. This redesign may include healthcare processes, e.g. clinical flows, analytical techniques to advise processes, e.g. intelligent models, information technology support for processes, and new management structures to facilitate the implementation and operation of the redesigns. Such methodology was applied to a large hospital specialized in cancer to illustrate its use and the results that can be achieved. Results show that the potential cost savings of new designs are about US$ 1.0 million yearly. To generate such savings, new medical and management practices were designed with the MDs’ participation. The implementation of the practices and their continuous evaluation and innovation was possible by a new organizational structure designed for such purpose. This work shows the importance of integrating several methodologies to generate better-founded designs. This integration is lacking in health-service design research, particularly in connection with architecture, processes, and organizational structure; this paper shows that this is a promising line of application.
Profile of the Multicenter Cohort of the German Cancer Consortium’s Clinical Communication Platform
Authors: Maier Daniel , Vehreschild Jörg Janne , Uhl Barbara , Meyer Sandra , Berger-Thürmel Karin , Boerries Melanie , Braren Rikmer , Grünwald Viktor , Hadaschik Boris , Palm Stefan , Singer Susanne , Stuschke Martin , Juárez David , Delpy Pierre , Lambarki Mohammed , Hummel Michael , Engels Cäcilia , Andreas Stefanie , Gökbuget Nicola , Ihrig Kristina , Burock Susen , Keune Dietmar , Eggert Angelika , Keilholz Ulrich , Schulz Hagen , Büttner Daniel , Löck Steffen , Krause Mechthild , Esins Mirko , Ressing Frank , Schuler Martin , Brandts Christian , Brucker Daniel P , Husmann Gabriele , Oellerich Thomas , Metzger Patrick , Voigt Frederik , Illert Anna L , Theobald Matthias , Kindler Thomas , Sudhof Ursula , Reckmann Achim , Schwinghammer Felx , Nasseh Daniel , Weichert Wilko , von Bergwelt-Baildon Michael , Bitzer Michael , Malek Nisar , Öner Öznur , Schulze-Osthoff Klaus , Bartels Stefan , Haier Jörg , Ammann Raimund , Schmidt Anja Franziska , Guenther Bernd , Janning Melanie , Kasper Bernd , Loges Sonja , Stilgenbauer Stephan , Kuhn Peter , Tausch Eugen , Runow Silvana , Kerscher Alexander , Neumann Michael , Breu Martin , Lablans Martin , Serve Hubert 
Published: January 2023

Abstract
Treatment concepts in oncology are becoming increasingly personalized and diverse. Successively, changes in standards of care mandate continuous monitoring of patient pathways and clinical outcomes based on large, representative real-world data. The German Cancer Consortium’s (DKTK) Clinical Communication Platform (CCP) provides such opportunity. Connecting fourteen university hospital-based cancer centers, the CCP relies on a federated IT-infrastructure sourcing data from facility-based cancer registry units and biobanks. Federated analyses resulted in a cohort of 600,915 patients, out of which 232,991 were incident since 2013 and for which a comprehensive documentation is available. Next to demographic data (i.e., age at diagnosis: 2.0% 0–20 years, 8.3% 21–40 years, 30.9% 41–60 years, 50.1% 61–80 years, 8.8% 81 + years; and gender: 45.2% female, 54.7% male, 0.1% other) and diagnoses (five most frequent tumor origins: 22,523 prostate, 18,409 breast, 15,575 lung, 13,964 skin/malignant melanoma, 9,005 brain), the cohort dataset contains information about therapeutic interventions and response assessments and is connected to 287,883 liquid and tissue biosamples. Focusing on diagnoses and therapy-sequences, showcase analyses of diagnosis-specific sub-cohorts (pancreas, larynx, kidney, thyroid gland) demonstrate the analytical opportunities offered by the cohort’s data. Due to its data granularity and size, the cohort is a potential catalyst for translational cancer research. It provides rapid access to comprehensive patient groups and may improve the understanding of the clinical course of various (even rare) malignancies. Therefore, the cohort may serve as a decisions-making tool for clinical trial design and contributes to the evaluation of scientific findings under real-world conditions.
Did real economic uncertainty drive risk connectedness in the oil–stock nexus during the COVID-19 outbreak? A partial wavelet coherence analysis
Authors: Al-Shboul Mohammad , Maghyereh Aktham 
Published: January 2023

Abstract
The paper extends the literature by examining whether real economic policy (the business condition risk (ADS)) can derive the risk connectedness in the oil–stock nexus during the COVID-19 outbreak using the multivariate wavelet coherency (MWC) and partial wavelet coherency (PWC) methods. The wavelet methods allow to isolate the effect of different global risk indices (such as the US economic uncertainty index (EPU), the crude oil volatility index (OVX), and the geopolitical risk index (GPR)) on the level of risk connectedness. Based on the daily data for the period January 2018–December 2020, we find that very strong impact of real economic uncertainty indices on risk connectedness. This impact is time-varying and frequency-sensitive, and it exhibits event-specific patterns. We find stronger MWC and PWC between real economy uncertainty indices and risk connectedness at lower frequencies. However, during the coronavirus disease 2019 (COVID-19) crisis, higher coherencies are found at higher frequencies; conditional to the effect of each global risk factor (EPU, GRP, and OVX), we also find higher PWC between oil and equity volatilities at lower frequencies. This study provides useful guidance to regulators and portfolio risk diversifiers.
JEL Classifications : G12; G15; G18 ; G01; F3; E44
Understanding experiences of mental health help-seeking in Arab populations around the world: A systematic review and narrative synthesis
Authors: Khatib Hania El , Alyafei Aisha , Shaikh Madiha 
Published: January 2023

Abstract
Background: Racial and ethnic disparities in mental health service utilisation and access is well established. Mental illness is common among Arab populations globally, but most individuals display negative attitudes towards mental health and do not seek professional help. The aim of this systematic review was to determine 1) help-seeking behaviours 2) help-seeking attitudes and 3) help-seeking barriers and facilitators, related to mental health services among Arab adults.
Method: A pre-defined search strategy and eligibility criteria allowed for database searching using terms related to: mental health, Arabs, help-seeking, as well as experiences and behaviours. Seventy-four articles were included and analysed through narrative synthesis. Results were reported using the PRISMA guidelines. The review protocol was registered prospectively on PROSPERO (CRD42022319889).
Results: Arabs across the world have negative attitudes towards formal help-seeking and are reluctant to seek help, despite the presence of psychological distress. There is little information on factors that influence help-seeking behaviours and rates of service use. Preference for informal help sources such as family and friends were expressed and considered more acceptable. Low mental health literacy, stigma, gender, age, education, religion, acculturation, and immigrant status were the most common factors influencing help-seeking attitudes. Barriers to help-seeking included stigma, privacy and confidentiality, trust, mental health literacy, language, logistics, and culture related barriers. Increasing societal and family awareness, external support and encouragement, shared culture between the client and therapist, quality of doctor patient relationship, and feelings of connectedness with the host country among refugees were mentioned facilitators. Mixed findings for the role of religion, and family and community, in relation to facilitating or hindering help-seeking were reported.
Conclusions: There is an increased likelihood and preference to seek informal sources of psychological support among Arabs. Contextual and cultural factors impeding help-seeking for Arabs are common across the world. Future research should address actual utilisation rates of services to better understand factors that influence help-seeking behaviours and facilitators to help-seeking. Increasing mental health literacy and developing anti stigma campaigns is necessary. Developing culturally informed interventions should inform future efforts to promote help-seeking among this population.
Evaluating Culture and Arts from an Economic Point of View
- Calculation of the cultural GDP of Kyoto Prefecture in 2015
Authors: Zhang Heming , Ishiro Taku 
Published: January 2023

Abstract
This paper aims to evaluate the culture and arts of the Kyoto prefecture from the economic point of view through the calculation of the cultural GDP of Kyoto prefecture in 2015. The method for calculating the cultural GDP in Japan is mainly based on the criterion of the UNESCO’s Cultural Satellite Account (CSA). Results reveal that the ratio of the cultural GDP to the total GDP in Kyoto prefecture is slightly higher than that of the whole country in Japan and each domain shows different characteristics from the national situation. Considering the growth strategies of cultural industries formulated by Japanese government, Kyoto prefecture should focus on developing its main industry and vigorously promote its cultural industries as well as activate the development of the traditional culture.
Association between regional dietary patterns and cardiovascular health status among elderly in China
Authors: Jiao Yingying , Li Weiyi , Jia Xiaofang , Wang Zhihong , Wang Huijun , Zhang Bing , Jiang Hongru , Ding Gangqiang 
Published: January 2023

Abstract
Objectives To evaluate the cardiovascular health (CVH) status of the elderly and analyze the effects of dietary patterns and demographic characteristics on CVH.
Methods A total of 4299 individuals aged 60 years and above from the China Health and Nutrition Survey in 2018 were selected as the research objects. Cluster analysis was used to analyze the dietary patterns. The definition of "Life’s Essential 8" of CVH released by American Heart Association (AHA)in 2022 was used to evaluate CVH status. Finally, multinomial logit model was used to analyze the impact of demographic economic characteristics on CVH.
Results Three dietary patterns were obtained by cluster analysis. In pattern 1, the intake of wheat, other grains, tubers and legumes was higher. Pattern 2 was dominated by high intake of aquatic products, vegetables and fruits; Pattern 3 was dominated by higher intake of rice and livestock meat. The total CVH score was 68.50, and sleep and blood pressure had the highest and lowest scores (85.85 and 37.64). Pattern 1 and Pattern 2 have slightly higher CVH scores. There were 16%-18% of the elderly with high CVH, and there was no significant difference in the distribution of high, moderate and low CVH among the three patterns (p=0.29). More than 50% of the elderly have 3-4 ideal metrics, 0.2% of the elderly have all 8 metrics reached the ideal state only in pattern 1. Multinomial logit analysis showed that the elderly in pattern 2 had 6-8 ideal metrics, which was 1.81 times higher than that in pattern 1; The presence of 6-8 ideal metrics in female was 3.42 times higher than that in male; Those with a college degree and above have 6-8 ideal metrics, which was 1.99 times of those with a primary school degree and below. Compared with 60-69 years, the presence of 6-8 ideal metrics in 70 years and above was 35% lower (OR=0.65,95%=0.49-0.87). The presence of 6-8 ideal metrics in high income group were 31% lower than those in low income group (OR=0.69,95%=0.47-1.00).
Conclusions The elderly in China were in moderate CVH. Dietary pattern characterized by higher intake of aquatic products, vegetables and fruits were more likely to have more ideal CVH metrics. It is necessary to take targeted intervention measures for the elderly and health factors with low scores to promote the improvement of CVH status.