bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Evaluation of Curcumin-loaded Niosomal Gel for
Wound Healing in Rats
Authors: Ahmad Asad , Akhtar Juber , Ahmad Mohammad , Khan Mohammad Irfan , Badruddeen  , Singh Aditya 
Published: July 2023

Background:
The process of wound healing is a complicated series of organized biochemical and cellular phenomena that restore the integrity of the skin and subcutaneous tissue. A drug molecule can be transported to the site of action through a variety of carriers, including niosomes or non-ionic surfactant vesicles. They can trap medications that are both hydrophilic and hydrophobic. It has been demonstrated that curcumin has strong analgesic, anti-inflammatory, and wound-healing qualities.

Methods:
In the current study, an effort has been made to create a curcumin-loaded niosomal gel for efficient wound healing therapy. Utilizing non-ionic surfactants (Span 60, Span 20, Tween 20, and Tween 60) and cholesterol at various concentrations, a modified thin-film hydration process was used to create niosomal gels containing curcumin. Particle size, shape, entrapment effectiveness, deformability, and in vitro skin penetration were used to describe the vesicles. The 1% carbopol 940 gel was then made using the improved formulation. In wound-induced rats, the effectiveness of the in vivo wound healing was assessed.

Results:
The manufactured niosomes were discovered to be homogeneous in size and spherical in shape. According to the IR spectrum study, the medication and formulation additives did not interact. It was discovered that the niosomal gel (S-3) loaded with curcumin was not irritating to the skin. According to studies on in vivo wound healing, curcumin-loaded niosomal gel exhibited the highest percentage of wound contraction. Following 21 days of niosomal gel treatment, the histopathological evaluation found a noticeable improvement in the skin's histological architecture. Curcumin-loaded niosomal gel was easily made using the thin film hydration process.

Conclusion:
The results of this study demonstrate the potential of niosomal gel as a cutting-edge therapeutic strategy for wound healing.
Exploring Patient Advisors’ Perceptions of Virtual Care Across Canada: Qualitative Phenomenological Study
Authors: Braund Heather , Dalgarno Nancy , Chan-Nguyen Sophy , Digby Geneviève , Haji Faizal , O'Riordan Anne , Appireddy Ramana 
Published: July 2023

Background
While virtual care services existed prior to the emergence of COVID-19, the pandemic catalyzed a rapid transition from in-person to virtual care service delivery across the Canadian health care system. Virtual care includes synchronous or asynchronous delivery of health care services through video visits, telephone visits, or secure messaging. Patient advisors are people with patient and caregiving experiences who collaborate within the health care system to share insights and experiences in order to improve health care.

Objective
This study aimed to understand patient advisors’ perceptions related to virtual care and potential impacts on health care quality.

Methods
We adopted a phenomenological approach, whereby we interviewed 20 participants who were patient advisors across Canada using a semistructured interview protocol. The protocol was developed by content experts and medical education researchers. The interviews were audio-recorded, transcribed verbatim, and analyzed thematically. Data collection stopped once thematic saturation was reached. The study was conducted at Queen’s University, Kingston, Ontario. We recruited 20 participants from 5 Canadian provinces (17 female participants and 3 male participants).

Results
Six themes were identified: (1) characteristics of effective health care, (2) experiences with virtual care, (3) modality preferences, (4) involvement of others, (5) risks associated with virtual care encounters, and (6) vulnerable populations. Participants reported that high-quality health care included building relationships and treating patients holistically. In general, participants described positive experiences with virtual care during the pandemic, including greater efficiency, increased accessibility, and that virtual care was less stressful and more patient centered. Participants comparing virtual care with in-person care reported that time, scheduling, and content of interactions were similar across modalities. However, participants also shared the perception that certain modalities were more appropriate for specific clinical encounters (eg, prescription renewals and follow-up appointments). Perspectives related to the involvement of family members and medical trainees were positive. Potential risks included miscommunication, privacy concerns, and inaccurate patient assessments. All participants agreed that stakeholders should be proactive in applying strategies to support vulnerable patients. Participants also recommended education for patients and providers to improve virtual care delivery.

Conclusions
Participant-reported experiences of virtual care encounters were relatively positive. Future work could focus on delivering training and resources for providers and patients. While initial experiences are positive, there is a need for ongoing stakeholder engagement and evaluation to improve patient and caregiver experiences with virtual care.
Calidad de la información de los promocionales de la industria farmacéutica y la educación médica
Authors: Peredo-Silva Luis , Reyes-Morales Hortensia , Guizar-García Luis Alberto , Almeida-Gutiérrez Eduardo , Páez-Moreno Ricardo , Lifshitz Alberto , Mino-León Dolores 
Published: July 2023

Introducción: El 15% de los promocionales de la industria farmacéutica (IF) incluyen información que no se fundamenta con los resultados del artículo original.
Objetivo: Evaluar la validez de los artículos científicos originales que sustentan la información de los promocionales de la IF dirigidos a internistas y cardiólogos y conciliar la información del artículo científico original con la del promocional.
Método: Los promocionales se obtuvieron en los congresos nacionales de Medicina Interna (MI) y Cardiología (C) realizados en México; aleatoriamente se seleccionaron 10 de cada especialidad; tres investigadores evaluaron la calidad de las referencias bibliográficas, la validez de los artículos originales y realizaron la conciliación de la información. Se realizó análisis descriptivo.
Resultados: Se recolectaron 57 promocionales de MI y 16 de C; la calidad de las referencias bibliográficas de 4 promocionales de MI se evaluaron como evidencia “moderada” y las referencias de 4 promocionales de C como evidencia “no científica”. Los ensayos clínicos controlados de MI y C fueron válidos, un estudio observacional de C se catalogó sin validez. La conciliación de la información del promocional con la del artículo original reveló diferencias en cuatro promocionales de cada especialidad y de acuerdo con los criterios éticos para la promoción de medicamentos de la Organización Mundial de la Salud (OMS) predominó la falta de exactitud, en algunos casos la información no fue fidedigna y/o verdadera.
Conclusiones: Es importante capacitar al médico en lectura crítica, para que evalúe objetivamente la información e identifique la promoción de medicamentos inefectivos y/o inseguros.
Actitudes y percepciones de los estudiantes de Odontología sobre la educación a distancia
Authors: Castro-Rodríguez Yuti 
Published: July 2023

Introducción: La educación a distancia ha sido instaurada en múltiples universidades debido al contexto de la pandemia de COVID-19 y es discutido si presenta impactos positivos en el campo de Odontología.
Objetivo: Identificar las actitudes y percepciones de los estudiantes de Odontología sobre la educación a distancia.
Método: Estudio transversal comparativo que incluyó a estudiantes de la Facultad de Odontología de la Universidad Nacional Mayor de San Marcos (Lima, Perú). Se utilizó una escala de actitudes hacia el aprendizaje, un cuestionario de datos personales y preguntas abiertas. Los datos de la escala se presentaron como frecuencias relativas según respuesta global y puntuaciones promedio. Estos datos se compararon con las características de los estudiantes.
Resultados: Fueron encuestados 216 estudiantes, 120 (55.6 %) mujeres. El 34.7 % (n = 75) estuvo en desacuerdo al afirmar que la educación a distancia es más eficaz que el aprendizaje presencial, el 24.5 % (n = 53) sí estuvo de acuerdo. Los varones estuvieron más satisfechos con la educación a distancia (3.91 ± 1.02); las puntuaciones de esta satisfacción fueron más elevadas para los estudiantes de primer y segundo año, así como para aquellos que cursaban asignaturas teóricas (3.94 ± 1.12). Los estudiantes que recibieron asignaturas teóricas, prácticas y clínicas evidenciaron bajas puntuaciones respecto a la pregunta “Creo que no he aprendido bien con la educación a distancia” (3.01 ± 0.12).
Conclusiones: La mayoría de estudiantes de Odontología de una universidad pública peruana presentan actitudes de desacuerdo respecto a la eficacia de la educación a distancia sobre la educación presencial, principalmente por estudiantes de años superiores y aquellos que han llevado asignaturas teórico-prácticas y clínicas. La mayoría de estudiantes sí recomienda el uso del modelo educativo a distancia para llevar asignaturas teóricas, que no demanden sesiones prácticas donde se desarrollen habilidades psicomotrices y que se desarrolle una asignatura al día.
The Implementation of Effective Online Asynchronous Corrective Feedback on the Oral Production of English as a Foreign Language Learners in University Virtual Speaking Classes
Authors: Ugalde Ramos Óscar Abel 
Published: July 2023

This article had as main aim that of identifying the effectiveness of asynchronous corrective feedback on the oral production of university students taking an online integrated English course as part of their program. All research instruments and tested corrective feedback method were applied in the speaking section of the course that had a duration of sixteen weeks. The study followed a mixed-methods design, where qualitative data was gathered by means of a leaners’ speech analysis scale, while quantitative data was gathered through a questionnaire addressing language learners´ preferences in relation to corrective feedback in oral English classes. A first oral test and final oral test were also used as pre-test and post-test to measure the level of improvement after the intervention phase. Opposed to Nunan’s (1992) position towards the use of positive feedback instead of corrective feedback, the present research project was underlaid by the conception that teachers’ reactions and reflections on learners’ deviant forms of the target language are a crucial part of the whole language learning spectrum. Very interesting findings were shed, first, for the two main types of errors analyzed in the study (Grammar and Vocabulary, and Pronunciation), there was a diminution in quantity when comparing the results from the first exam to those of the final exam, representing those learners committed 10% less errors in the final oral exam. Unsurprisingly, students unanimously favored the use of corrective feedback in their language classes. However, preferences on synchronous and asynchronous corrective feedback showed no major difference.
Gêneros textuais na EJA: um estudo com contos de assombração
Authors: Borba Valquíria Claudete Machado 
Published: July 2023

O presente artigo é uma reflexão sobre os gêneros textuais em sala de aula a partir de um trabalho com contos de assombração em duas turmas de terceira fase de EJA (Educação de Jovens e Adultos). Analisando os dados, pensando na realidade que encontramos em sala de aula, tecemos algumas considerações sobre gêneros textuais, leitura e escrita na EJA.
Ergonomic Risk Assessment of Nigerian Teaching Personnel: Cases of a Secondary School and a Tertiary Institution in Ibadan, Nigeria
Authors: Bolarinwa Mojisola A. , Kumapayi Adeola O. 
Published: July 2023

Educators often spend a lot of time carrying out repetitive motions of the upper limbs and prolonged standing on a daily basis, exposing them to hours of ergonomic risks. This is due to awkward postures, caused by significant deviation of some major body members from the normal neutral positions. Poor ergonomics can lead to various Musculoskeletal Disorders (MSDs), which are of serious concern for workplace safety, especially in jobs that require repetitive motions. It thus became necessary to assess the stress level associated with teaching postures and the prevalent musculoskeletal discomfort in different parts of the body. In this study, ergonomic assessment of teaching personnel at an International Secondary School and University of Ibadan, Nigeria was conducted to determine the prevalent musculoskeletal discomfort in different parts of the body. The study utilised two ergonomic assessment tools- Rapid Entire Body Assessment (REBA) and Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) to gather qualitative and quantitative data about posture and motions during teaching activities. It was discovered that both university lecturers and secondary school teachers in Nigeria face significant ergonomic risks, primarily in the neck, shoulders, and lower back. Further comparison revealed that educators in the secondary school experienced higher severity of musculoskeletal discomfort and exposure to MSD risks, compared to those in the tertiary institution. The educators of the International School had an average REBA score of 4.57, while those at the University of Ibadan had a score of 3.73. These scores indicated a medium level of MSD risk for both groups, but the educators of the International School were at a higher risk. On comparing the CMDQ outcome, it was discovered that there were major differences in the regions where discomforts were reported. While secondary school revealed higher average scores in the neck, right shoulder, and left shoulder regions, and with the neck region having a mean score of 7.003; right shoulder having a mean score of 4.550; and left shoulder having a mean score of 1.600; outcome from University of Ibadan revealed higher mean scores in the lower back and left wrist regions, with the lower back region having a mean score of 7.450 and left wrist region having a mean score of 1.030. These scores indicated a mild to moderate level of discomfort for both groups, with each facing major discomfort in unique body regions. This research highlights the significance of ergonomic evaluation and the combination of quantitative and qualitative data to identify potential interventions.
The Effect Of High-Intensity Exercise Training On Serum Calcium Of Female Combat Athletes
Authors: Hoseini Ravesh Seyed Mohammad , Moghadam Masha Nakhaei 
Published: July 2023

Purpose: Cell homeostasis is an essential factor in maintaining cellular health and intracellular mechanisms, which can also be associated with inflammatory factors and increased stress for muscle cell health. Calcium is also a necessary factor in cell health and is to establish homeostasis in the body. This study aimed to investigate the effect of high-intensity training on serum calcium levels in combat women. Method: For this purpose, 18 women karateka in the age range of 17 to 23 years were randomly divided into 2 groups: control (n=7) and exercise ((n=11). The exercise group performed proper exercises to improve karate and aerobic techniques for 6 weeks in the intensities of more than 80% of the maximum heart rate reserve. Physiological indices and blood samples were measured 24 hours before and 48 hours after the training protocol. To measure calcium cell biomarker, the Pars Azmoon calcium kit was used. Research data were analysed by covariance test at the significant level (P≤0.05) using SPSS software version 25. Results: After six weeks of high-intensity training, there was a significant difference in serum calcium levels in the exercise group compared to the control group (P = 0.002). Also, the results within the group showed a significant increase in serum calcium (P = 0.016) in the exercise group compared to baseline conditions. Conclusions: High intensity training seems to increase serum calcium in female athletes, and this can lead to precursors to cellular disorders, muscle damage and increase inflammatory factors and ultimately decrease the performance of female athletes. However, more research is essential in this regard.
Academic Motivation of Highschoolers During Distance Learning: The Contribution of Perceived Social Support and Grit
Authors: Salim Rose Mini Agoes , Ginandra Regia Lidwina , Rumalutur Nur Aisyah 
Published: July 2023

The changing in learning activities from face-to-face classes to distance learning has brought a decrease in student’s enthusiasm and involvement. This change might also cause a decrease in academic motivation among high school students. Academic motivation could be increased by internal factors, namely perceptions of social support and grit. This study aimed to examine the contribution of perceived social support and grit on academic motivation. This study’s measurements utilized: (1) the Academic Motivation Scale (AMS) for academic motivation; (2) Social Provisions Scale (SPS) for perceived social support; and (3) Grit Short Scale (GRIT-S) for grit. Data was obtained using a series of questionnaire distributed online. This study involved total of 222 high school students undergoing distance learning. Based on a multiple linear regression analysis, it was found that perceived social support and grit had a significant contribution of 8.7% to academic motivation (F = 10.392; R² = .087; Adjusted R² = .078; p = .05). Therefore, related parties need to maintain and develop social support and grit for students so that academic motivation can remain good even when faced with distance learning conditions.

Perubahan kegiatan belajar menjadi pembelajaran jarak jauh (PJJ) membawa berbagai perubahan yang dapat menyebabkan menurunnya semangat dan keterlibatan, karena menurunnya motivasi akademik pada siswa sekolah menengah atas (SMA). Motivasi akademik dapat ditingkatkan dengan faktor internal, yaitu persepsi terhadap dukungan sosial dan grit. Studi ini ingin melihat kontribusi dari persepsi terhadap dukungan sosial dan grit secara bersamaan pada motivasi akademik. Pengukuran variabel studi ini dilaksanakan menggunakan: (1) motivasi akademik dengan Academic Motivation Scale (AMS); (2) persepsi terhadap dukungan sosial dengan Social Provisions Scale (SPS); dan (3) grit dengan Grit Short Scale (GRIT-S). Data studi ini didapatkan dengan menggunakan kuesioner yang disebarkan secara daring. Sebanyak 222 partisipan yang sedang menjalani pembelajaran jarak jauh (PJJ) dilibatkan dalam studi ini, dan berdasarkan analisis multiple linear regression, didapatkan hasil bahwa persepsi terhadap dukungan sosial dan grit secara bersamaan memiliki kontribusi yang signifikan senilai 8,7% terhadap motivasi akademik (F = 10,3; R² = 0,087; Adjusted R² = 0,078; p < 0,05). Maka dari itu, penting bagi pihak terkait untuk menjaga dan mengembangkan dukungan sosial dan juga grit pada siswa agar motivasi akademik dapat tetap baik walaupun dihadapkan pada kondisi pembelajaran jarak jauh (PJJ).
OBITUARY: Jill Jolliffe: Running for her life
Authors: Gruber Fiona 
Published: July 2023

Journalist and author Jill Jolliffe’s work took her around the world, including 16 years in Portugal, reporting on corruption and injustices, including the killing of five Australian, British and New Zealand journalists at Balibo on the eve of the Indonesian invasion of Timor-Leste in 1975. Her commitment to East Timorese independence endured over decades. Paying tribute, Timorese leader Xanana Gusmão, said: ‘Jill was an activist, a rebel and a fighter . . . She is one of us.’
REVIEW: Learning from Oceania peace activists
Authors: Devere Heather 
Published: July 2023

Peace Action: Struggles for a decolonised and demilitarised Oceania and East Asia, edited by Valerie Morse. Te Whanganui-A-Tara (Wellington): Left of the Equator Press, 2022, 178 pages. ISBN 9780473634452.
THE AIMS of Peace Action as stated by the editor, Valerie Morse, are ‘to make visible interconnections between social struggles separated by the vast expanse of Te Moana Nui-A-Kiwi [the Pacific Ocean] … to inspire, to enrage and to educate, but most of all, to motivate people to action’ (p. 11). It is an opportunity to learn from the activists involved in these struggles.
REVIEW: SAS exposé a masterclass in investigative journalism
Authors: Lidberg Johan 
Published: July 2023

Crossing The Line: The inside story of murder, lies and a fallen hero, by Nick McKenzie. Sydney: Hachette Australia. 2023. 454 pages. ISBN 9780733650437
I WILL forever remember choking on my morning coffee when I read The Age on 8 June 2018. Nick McKenzie and Chris Master’s article detailing the alleged war crimes in Afghanistan of a highly decorated Australian war hero was confronting, to say the least. ‘This is crazy brave,’ I remember thinking. ‘I really hope they’ve done their homework.’
Participation of Healthy Volunteers in Clinical Trials &ndash; Motives, Barriers and Ethical Issues
Authors: Asghar Raja Sajjad , Saleem Javeria , Ishaq Muhammad 
Published: July 2023

<p>Recruitment of adequate number of healthy volunteers is vital for success of clinical trials but there is limited research on factors motivating the healthy volunteers to participate in clinical trials especially in developing countries. Pakistani researchers also faced the problems in enrollment of enough healthy volunteers during COVID-19 pandemic when a number of clinical trials began in Pakistan. Around 117 research proposals were processed by the National Bioethics Committee (NBC) of Pakistan in last two years. A major proportion of these clinical research studies target healthy populations as primary research subjects or as controls.</p>
<p>Numerous studies have investigated factors such as motives, barriers, risks. benefits and ethical values affecting recruitment and participation of healthy volunteers in clinical trials. We have reviewed the literature to learn about factors that motivate or prevent the healthy persons to volunteer along with the pertaining ethical issues.</p>
<p>Financial incentive is the principal motive for healthy volunteers to participate in clinical trials along with altruism, contribution to sciences, research and other people&rsquo;s health, desire to take part in something important, learning more about science and medicine, access to healthcare &amp; free medical checkup and prospects of one&rsquo;s social network expansion whereas time inconvenience, confidentiality, possible side effects &amp; route of administration of drug and fear of contacting the disease were identified as important barriers.</p>
<p>Application of knowledge of these motives and barriers will help Pakistani researchers to enroll adequate number of healthy volunteer for their clinical trials.</p>