bluuebunny/crossref_metadata_2025_split huggingface dataset:
The methylene blue and phenol red photocatalytic degradation study by cyclodextrin-ZnO nanostructures
Authors: Gharebaghi Azar , Magham Abbas Heshmati Jannat , Hokmabadi Leila 
Published: August 2023

Abstract
Photocatalytic processes are able to decompose dyes and toxic substances in the water environment. This fascinating topic can address many environmental concerns about polluted water. Zinc oxide is widely used as a photocatalyst in various nanocomposites.In this study, the formation of a nanostructure including cyclodextrin and ZnO has been investigated by density functional theory (DFT) in gas and aqueous phases at B3LYP and M06-2X functional levels. The calculated binding energies and natural bond orbital (NBO) analysis indicate the existence of strong chemical interactions of ZnO with inside of the cyclodextrin (CD) cavity during CD-ZnO formation. In addition, the interaction of methylene blue (MB) and phenol red (PhR) dyes with CD-ZnO nanostructure has been investigated. The dyes’ adsorption energies on the CD-ZnO and the density of states diagrams in their complexes, confirm the strong interaction of MB and PhR with CD-ZnO. This strong interaction of dyes with nanostructure can support the mechanisms that lead to the photocatalytic degradation of dye molecules.
Relationship between Abnormal Spontaneous Brain Activity and Altered Neuromuscular Activation of Lumbar Paraspinal Muscles in Chronic Low Back Pain
Authors: Zhang Shanshan , Wang Yanjun , Li Tingting , Ma Junqin , He Rongxing , Han Xiulan , Wu Wen , Wang Chuhuai 
Published: August 2023

Abstract

Background
Chronic low back pain (cLBP) affects brain functional activity of the descending pain modulatory network and altered synergistic activation of lumbar paraspinal muscles. However, the neural mechanism underlying functional reorganization and effectiveness of cooperative motion remains unexplored.
Methods
Fifteen cLBP patients and fifteen healthy controls underwent whole brain blood oxygen level-dependent signals measured by functional magnetic resonance imaging technique and amplitude of low-frequency fluctuation (ALFF) analysis method to identify pain-induced changes in regional spontaneous brain activity. A novel approach based on the surface electromyography system and fine-wire electrodes was used to record the EMG signals in the deep multifidus, superficial multifidus and erector spinae.
Results
ALFF was higher in the medial prefrontal cortex, primary somatosensory cortex, motor cortex and inferior temporal cortex in cLBP than at the baseline, whereas lower in the cerebellum, anterior cingulate cortex and posterior cingulate cortex. Further, the decrease in the average electromyography of three lumbar muscles in the cLBP group was positively correlated with the ALFF values of the primary somatosensory cortex, motor cortex, precuneus and middle temporal cortex, but significantly negatively correlated with the medial prefrontal cortex and inferior temporal cortex. Interestingly, the correlation between the functional activity in the cerebellum and the electromyography activity varied in lumbar muscles.
Conclusion
These findings suggest a functional association between abnormal spontaneous brain activity and altered voluntary neuromuscular activation patterns of the lumbar paraspinal muscles, providing new insights into the underlying mechanisms of pain chronicity and important implications for developing novel therapeutic targets of cLBP patients.
Spatiotemporal patterns and influencing factors of intangible cultural heritage of music in the "Yellow River—Yangtze River Civilization Corridor", China
Authors: Tian Yonggang , Chen Mo , Liu Yuan 
Published: August 2023

Abstract
The "Yellow River—Yangtze River Civilization Corridor" is an important cultural corridor in China that gathers the main cultural heritage resources along China's two river basins. The space-time distribution of intangible cultural heritage in the "Yellow River–Yangtze River Civilization Corridor" significantly helps understand the development and evolution of China's two river civilizations. This study examines 3,277 national and provincial intangible cultural heritage sites related to music in the Yellow River and Yangtze River basins of China. The spatial and temporal distributions of intangible cultural heritage of music (ICHM) were visualized by means of the nearest neighbour index, kernel density analysis, standard deviation ellipse and geographical detector, and the influencing factors were discussed. The results show the following: (1) The spatial distributions of ICHMs in the "Yellow River—Yangtze River Civilization Corridor" are significantly different, with a high concentration in the central region, where the largest number of traditional dance and the smallest number of quyi arts are located. (2) The "Yellow River–Yangtze River Civilization Corridor" ICHMs are agglomerated, forming a pattern of "one area and four points" in the combined area of western Shandong—southern Henan—southern Shanxi—central Shaanxi, along with Jiangsu, Jiangxi, Hubei and Chongqing. The distributions of various ICHMs are different. (3) The historical development of ICHMs of the "Yellow River—Yangtze River Civilization Corridor" generally presents the changing characteristics of "two peaks and three valleys", which articulate a peak in artistic production in the pre-Qin to Qin and Han dynasties, and another in the Song and Yuan to Ming and Qing dynasties. Comparatively, production lies in a trough in prehistoric times, the Wei, Jin, Southern and Northern dynasties and in modern times. The overall trajectory of the centre of gravity of ICHMs shifts from northwest to southeast. (4) Population, an average temperature ≥ 10℃, GDP, elevation and annual rainfall play a leading role in the spatial distribution of ICHMs along the "Yellow River—Yangtze River Civilization Corridor". The synergistic effect of the social economy and natural environment is greater than the effect of single dimension factors on the spatial distribution of ICHMs in the "Yellow River-Yangtze River Civilization Corridor". The results provide a reference for policy-makers designing the protection, inheritance and sustainable development of ICHMs in the "Yellow River—Yangtze River Civilization corridor" and enrich the theoretical research and practical management of the world's river civilization ICHMs.
Association of exercise with better olfactory performance and higher functional connectivity between the olfactory cortex and the prefrontal cortex: a resting-state fNIRS study
Authors: Zhang Chenping , Wang Xiaochun 
Published: August 2023

Abstract
Background
Olfactory deterioration is suggested to be a predictor of some neurodegenerative diseases.
Methodology
: Our study compared the functional connectivity between the olfactory cortex and the prefrontal cortex in healthy individuals who exercised regularly and healthy persons who did not. We also assessed their odor threshold. Participants were aged 55 years or older, and the two groups were balanced for age, sex, body mass index, and educational level.
Results
We found that compared with individuals who did not exercise, exercisers had a significantly lower threshold for detecting odors. In addition, the olfactory cortex had stronger connectivity with the PFC in exercisers than in non-exercisers. More specifically, when the PFC was grouped into three subregions, namely, the ventrolateral prefrontal cortex (VLPFC), dorsolateral prefrontal cortex (DLPFC), and frontopolar cortex (FPA), Pearson correlation analysis revealed stronger connectivity between the VLPFC and the OFC, between the OFC and the FPA, and between the left and right OFC hemispheres in the exercisers. In addition, Granger causality indicated higher directional connectivity from the DLPFC to the OFC in exercisers than in non-exercisers.
Conclusion
Our findings indicate that the exercise group not only had better olfactory performance but also had stronger functional connectivity between the olfactory cortex and the PFC than non-exercise group.
Increased odds ratio for Bell’s palsy following COVID -19 infection or vaccination in a large Health Center
Authors: Katz Joseph , Sayman Eva 
Published: August 2023

Abstract
Objective: Bell’s palsy is a paralysis of the facial muscles on one side of the face caused by a viral infection. Studies have indicated an increase of Bell’s palsy following infection or vaccination for COVID-19. The study examined the association of these variables with Bell’s palsy in a large hospital cohort.
Materials and Methods: Using the deidentified data i2b2 of subjects visiting the University of Florida during October 2015- October 2022 we have identified subjects with an ICD-10 diagnoses of COVID -19, Bell’s palsy and vaccination for COVID-19.
Results: From a total population of 1314924, 38005 had a history of COVID-19, 2072 had a diagnosis of Bell’s palsy, 112 both Bell’s Palsy and COVID-19
and 196279 were vaccinated. Diagnosis of COVID-19 was associated with increased risk for Bell’s palsy (odds ratio 1.87, 95% CI 1.54 -2.26 p<0.0001). COVID -19 vaccination was associated with increased risk for Bell’s palsy at odds ratio1.98 (95%CI 1.79-2.18, p<0.0001).
COVID -19 infection or vaccination were associated with an increased risk for Bell’s palsy.
Conclusions:Although causality cannot be attributed to cross sectional studies, these findings may indicate that exposure to the viral antigen may be related to the neurological sequalae of COVID- 19.
Clinical Relevance: The Dental professionals should be aware of Bell’s palsy and the potential link of the appearance of Bell’s palsy post COVID-19 infection or vaccination
Identification and Characterization of Extrachromosomal Circular DNA in Age-Related Osteoporosis
Authors: Zhu Qingrun , Chen Rudong , Kuang Mingjie , Zhang Wen , Wang Dachuan , Han Shijie 
Published: August 2023

Abstract
Extrachromosomal circular DNA (eccDNA) was once thought to mainly exist in tumour cells, although it was later shown to be ubiquitous in healthy tissues as well. However, the characteristics and properties of eccDNA in healthy tissue or non-cancer tissue are not well understood. This study first analyses the properties, possible formation mechanisms and potential functions of eccDNA in osteoporotic or normal bone tissue. We used circle-seq to demonstrate the expression spectrum of the eccDNA in the bone tissue. A bioinformatics analysis was performed for the differentially expressed eccDNA, and it enriched the Hippo signalling pathway, PI3K-Akt signalling pathway, Ras signal-ling pathway and other signalling pathways that are closely related to osteoporosis (OP). Then, we used real-time polymerase chain reaction and Sanger sequencing to assess human bone marrow mesenchymal stem cells and obtained the base sequence of the eccDNA cyclization site. Overall, eccDNAs in bone tissue are common and may play a significant role in pathways connected to age-related osteoporosis progression.
Ictal Interictal Continuum in the pediatric intensive care unit
Authors: Sansevere Arnold , Keenan Julia , Pickup Elizabeth , Conley Caroline , Staso Katelyn , Harrar Dana 
Published: August 2023

Abstract

Introduction:
The ictal interictal continuum (IIC) is a common EEG pattern identified in critically ill adults. The IIC has not been systematically studied in critically ill children. We report the incidence of the IIC in the pediatric intensive care unit (PICU). We then compare IIC patterns to periodic and rhythmic patterns (PRP) not meeting IIC criteria looking for associations with cerebral injury, electrographic seizures (ES), and in-hospital mortality.
Methods
Prospective study of patients admitted to the PICU at Children’s National Hospital from July 2021 to January 2023. All patients with continuous EEG were screened for PRP. American Clinical Neurophysiology Society standardized critical care EEG terminology for the IIC were applied to each PRP. We excluded patients with epilepsy and/or remote cerebral injury. Associations between IIC and PRP not meeting IIC criteria, with clinical and EEG variables were calculated using odds ratios.
Results
Of 201 patients, 21% (42/201) had a PRP, and 12% (24/201) met IIC criteria. Among patients with an IIC pattern, the median age was 3.4 years (IQR 0.6–12). Sixty-seven percent (16/24) met a single IIC criterion, while the remainder met two criteria. ES were identified in 83% (20/24) and cerebral injury in 96% (23/24) of patients with IIC patterns. When comparing patients with IIC patterns to those with PRP not qualifying as an IIC pattern, both patterns were associated with cerebral injury (IIC OR 26(95% CI 3.4–197) p = 0.0016 vs. PRP OR 3.5(95% CI 1.1–11), p = 0.03), however only the IIC was associated with ES (OR 121(95% CI 33–451), p < 0.0001); vs PRP (OR 1.3(0.4-5), p = 0.7).
Conclusions
The IIC is seen in over 10% of critically ill children and suggests cerebral injury. The independent impact of the IIC on secondary brain injury requires further study.
Zinc supplementation trial in pediatric chronic kidney disease: effects on circulating FGF23 and Klotho.
Authors: Belostotsky Vladimir , Filler Guido , Atkinson Stephanie 
Published: August 2023

Abstract
Background Zinc status and its role in bone metabolism has not been studied in children with chronic kidney disease (CKD).
Methods Forty-one children (25 male and 16 female, age 12.94±4.13 years) with CKD in native or transplanted kidneys were recruited through two pediatric nephrology divisions in Ontario, Canada and their zinc status was assessed. 14 patients (64% enrolment rate) with identified zinc deficiency received zinc citrate supplement for 3 months in the dose of 10 mg orally once a day for age 4-8 years, and 10 mg twice a day for age 9-18 years.
Results Zinc deficiency (plasma concentration < 11.5 µmol/L) was found in 22 patients (53.7%). A linear regression model suggested that for every 1 unit drop of eGFR zinc concentration dropped by 0.026 µmol/L (p=0.04). Zinc deficiency was associated with higher serum intact FGF-23; however, this was predominantly determined by the falling GFR. Zinc deficient and sufficient children had similar circulating cFGF-23 and alpha-Klotho. Normalization of plasma zinc concentration was achieved in 8 patients rising from 9.96±1.48 to 12.39±3.89 μmol/L (p=0.0073). In children treated with zinc but not receiving calcitriol a statistically significant (p=0.0078) rise in c-terminal FGF-23 was observed. However, no other meaningful changes to biochemical measures or an increase in phosphaturia were observed.
Conclusion Zinc status is related to kidney function and connected to bone metabolism in patients with CKD. However, it plays a minor role in fine-tuning various metabolic processes and therapeutic supplementation seems to only modestly improve bone metabolism in asymptomatic CKD patients.
Analyses of POL30 (PCNA) reveal positional effects in transient repression or bi-fold active/silent state at the sub-telomeres of S. cerevisiae
Authors: Sauty Safia Mahabub , Yankulov Krassimir 
Published: August 2023

Abstract
Background
Classical studies on position effect variegation in Drosophila have demonstrated the existence of bi-modal Active/Silent state of the genes juxtaposed to heterochromatin. Later studies with irreversible methods for the detection of gene repression have revealed a similar phenomenon at the telomeres of Saccharomyces cerevisiae and other species. In this study, we used dual reporter constructs and a combination of reversible and non-reversible methods to present evidence for the existence of different states of gene repression at the sub-telomeres of S. cerevisiae.
Results
We show position dependent transient repression or bimodal expression of reporter genes at the VIIL sub-telomere. We also show that mutations in the replicative clamp POL30 (PCNA) or the destruction of the histone chaperone CAF1 or the RRM3 helicase lead to transient de-repression, while the destruction of the histone chaperone ASF1 causes a shift from transient de-repression to a bi-modal state of repression. We analyze the physical interaction of CAF1 and RRM3 with PCNA and discuss the implications of these findings for our understanding of the stability and transmission of the epigenetic state of the genes.
Conclusions
There are distinct modes of gene silencing, bi-modal and transient, at the sub-telomeres of S. cerevisiae. We characterise the roles of CAF1, RRM3 and ASF1 in these modes of gene repression. We suggest that the interpretations of past and future studies should consider the existence of the dissimilar states of gene silencing.
Evaluation of Conservation Tillage Methods on Soil and Water Conservation, and Yield and Yield Components of Maize (Zea mays L.) in South Ari District, Southern Ethiopia
Authors: Handiso Mitiku Ayele , Hemacho Abebe Hegano , Bongido Belayneh Lemage , Anjulo Merdikios Malla 
Published: August 2023

Abstract
Reduced tillage is one of the options to combat land degradation problems. The study aims to evaluate the impacts of tillage practice on selected soil physicochemical properties and soil loss, and maize yield and yield components. Four tillage treatments were evaluated, including zero tillage, two-times tillage, strip tillage, and farmers' practice were laid out in a randomized complete block design with five replications. Then, soil moisture, soil loss, and yield and yield components of maize data were collected. The results on soil moisture and soil loss revealed that conservation tillage methods were conducive to having better soil moisture contents during active crop development and after harvest compared to the conventional methods. The current findings also showed that adopting reduced tillage and zero tillage boosted maize yield and yield components with higher economic benefits to farmers in the long run as compared to strip tillage and conventional tillage. Although zero tillage attributed to less grain yield, it resulted in higher economic benefits to farmers and saved 44.84% soil loss reduction relative to conventional tillage. The economic evaluation result clearly showed that zero tillage, strip tillage and reduced tillage methods are better and recommendable for farmers, but reduced tillage is the best. Hence, farmers can use either zero tillage or reduced tillage, depending on their investment capital. But, to get considerable changes in soil and water balances, other soil physicochemical properties, and crop yields, conducting similar studies for more than two years period at permanent field plots is paramount in the future.
Improved intelligent methods for power transformer fault diagnosis based on tree ensemble learning and multiple feature vector analysis
Authors: Hechifa Abdelmoumene , Lakehal Abdelaziz , Nanfak Arnaud , saidi Lotfi , Labiod Chouaib , Kelaiaia Ridha , Ghoneim Sherif S. M. 
Published: August 2023

Abstract
This paper discusses the impact of the feature input vector on the performance of DGA-based intelligent power transformer fault diagnosis methods. For this purpose, 22 feature vectors from traditional diagnostic methods were used as feature input vectors for four tree-based ensemble algorithms, namely random forest (RF), tree ensemble (TE), gradient boosted tree (GBT), and extreme gradient tree (XGB). To build the proposed diagnostics models, 407 samples were used for training and testing. For validation and comparison with the existing methods of literature 89 samples were used. Based on the results obtained on the training and testing datasets, the best performance was achieved with feature vector 16, which consists of the gas ratios of Rogers’ four ratios method and the three ratios technique. The test accuracies based on these vectors are 98.37, 96.75, 95.93, and 97.56% for the RF, TE, GBT, and XGB algorithms, respectively. Furthermore, the performance of the methods based on best input feature were evaluated and compared with other methods of literature such as Duval Triangle, modified Rogers’ four ratios method, combined technique, three ratios technique, Gouda triangle, IEC 60599, NBR 7274, clustering, and key gases with gas ratio methods. On validating dataset, diagnostic accuracies of 92.13, 91.01, 89.89, and 91.01% were achieved by the RF, TE, GBT, and XGBoost models, respectively. These diagnostic accuracies are higher than 83.15 % of the clustering method and 82.02 % of combined technique which are the best existing methods. Even if the performance of DGA-based intelligent methods depends strongly on the shape of the feature vector used, this study provides scholars with a tool for choosing the feature vector to use when implementing these methods.
CiteSpace bibliometric-based analysis of fluorescent probes in brain diseases
Authors: Ren Yan , Chen Weikang , Wu Shasha , Zhang Ruiping 
Published: August 2023

Abstract
Background
Fluorescent probes are used to detect and label the corresponding substances and play an important role in the detection of brain diseases. However, the general research trends in this field are poorly understood. This article explores trends in the application of fluorescent probes in brain diseases from a bibliometric perspective.
Aim
This holistic bibliometric analysis aim to provide a general overview of the recent advancement and the hotspots in the field of fluorescent probe from 2002 to 2022.
Materials and Methods
Publication between January 1 2002 and December 31 2022, relate to fluorescent probes and brain diseases research are acquired from the Web of Science Core Collection (WOSCC) database. Analysis of the volume of keyword occurrences use VOSviewer software, Scimago Graphica software is applied to country analysis, and keyword clustering, author collaboration, and institutional collaboration use CiteSpace software.
Results
A total of 1927 publications are extracted from the WOSCC databases. Publications are mainly from China. The keywords are divided into seven clusters, including multiple sclerosis, tumor, oxidative stress, alzheimers disease, reactive oxygen species, plasma, infection; of which, gene, single nucleotide polymorphism, schizophrenia, haplotype, apolipoprotein e, bipolar disorder are the original research hotspot in the field. Peptide, biosensor, aggregation induced emission are the main areas researched in recent years.
Conclusion
Current research on fluorescent probes and brain disorders have attracted increasing attention in the past two decades. This study provides a comprehensive view to understand the research trends, hot topics of research and research progress in this field.