bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bilinear $\omega$-type Calder\'{o}n-Zygmund operator and its commutator on product of grand mixed generalized Morrey spaces
Authors: Lu Guanghui , Wang Miaomiao , Tao Shuangping 
Published: August 2023

Abstract
In this paper, we first introduce a grand mixed generalized Morrey spaces $M^{P),\Psi(\cdot)}_{u}(\mathbb{R}^{n})$, where $P=(p_{1},\cdots,p_{n})\in(1,\infty)^{n}$, $\Psi(\cdot)=(\psi_{1}(\cdot),\cdots,\psi_{n}(\cdot))$ is $n$-tuple of positive increasing functions $\psi_{i}$ defined on intervals $(0,p_{i}-1]$ for $i=1,\cdots,n$, and\\$u(X,r): \mathbb{R}^{n}\times(0,\infty)\rightarrow(0,\infty)$ is a Lebesgue measurable function; especially, if we take $\Psi(\Upsilon):=\Upsilon^{\Theta}$ with $0<\Upsilon:=(\varepsilon_{1},\cdots,\varepsilon_{n})0$, then the space $M^{P),\Psi(\cdot)}_{u}(\mathbb{R}^{n})$ is denoted by $M^{P),\Theta}_{u}(\mathbb{R}^{n})$. Furthermore, we establish the embeddingand density properties for the spaces $M^{P),\Psi(\cdot)}_{u}(\mathbb{R}^{n})$. Finally, as some applications, we prove that a bilinear $\omega$-type Calder\'{o}n-Zygmund operator$\widetilde{T}_{\omega}$ is bounded from the product of spaces $M^{P_{1}),\Theta}_{u_{1}}(\mathbb{R}^{n})\times M^{P_{2}),\Theta}_{u_{2}}(\mathbb{R}^{n})$ into spaces $M^{P),\Theta}_{u}(\mathbb{R}^{n})$; and also show that the commutator $\widetilde{T}_{\omega,b_{1},b_{2}}$ generated by $b_{1},b_{2}\in\mathrm{BMO}(\mathbb{R}^{n})$ and $\widetilde{T}_{\omega}$ is bounded from\\ the product of spaces $M^{P_{1}),\Theta}_{u_{1}}(\mathbb{R}^{n})\times M^{P_{2}),\Theta}_{u_{2}}(\mathbb{R}^{n})$ into spaces $M^{P),\Theta}_{u}(\mathbb{R}^{n})$, where $u_{1}u_{2}=u$ and $1<\infty$.Moreover, the boundedness of $\widetilde{T}_{\omega}$ and $\widetilde{T}_{\omega,b_{1},b_{2}}$ on the product of grand mixed Morrey spaces$M^{P_{1}),\Theta}_{q_{1}}(\mathbb{R}^{n})\times M^{P_{2}),\Theta}_{q_{2}}(\mathbb{R}^{n})$ is established.
Initiation of Dendritic Failure of LLZO via Sub-Surface Lithium Deposition
Authors: Siniscalchi Marco , Shi Yifu , Li Guanchen , Gibson Joshua , Bonilla Ruy , Speller Susannah , Grovenor Chris 
Published: August 2023

Abstract
The occurrence of lithium deposition in occluded spaces within ceramic electrolytes due to electronic leakage currents can jeopardise the commercialization of power-dense solid-state batteries. Here, we utilize plasma-FIB serial sectioning to visualize the surface and sub-surface of a garnet solid electrolyte (LLZO) after lithium plating. We study the morphology of surface spallation cracks, which represent the initial stage of dendrite formation. Employing a LiMg anode, we track the magnesium diffusion around these surface cracks with EDS. The absence of magnesium in early-stage cracks suggests they form due to the pressure build-up from the deposition of pure lithium in occluded pores near the electrolyte surface. These spallation cracks act as current focusing and stress concentration hot spots. Electron beam induced current imaging demonstrates that short-circuiting lithium dendrites grow from the spallations during plating. Thus, the sub-surface deposition of lithium is a possible explanation for the initiation of lithium dendrites in LLZO.
Hashimoto’s thyroiditis negatively influences IVF outcome in euthyroid women on T4 substitution therapy; a retrospective study
Authors: Herman Tünde , Török Péter , Laganà Antonio Simone , Chiantera³ Vito , Jakab Attila 
Published: August 2023

Abstract
Purpose: We retrospectively analyzed how the presence of thyroid autoimmunity (TAI positive) affected reproductive parameters in eighty-six (86) TAI positive women referred to IVF treatment.
Methods: All participants diagnosed with subclinical or overt hypothyroidism, while euthyroid on thyroxine replacement. Sixty-nine (69) female patients in the same IVF program, with no thyroid abnormalities served as controls (TAI negative group).
Results: Statistically significant baseline hormone profile differences were found in multiple parameters between the two groups. TAI positive women were older (mean age 34.7±5.42 vs. 32.32±5.04 years; p=0.002), had higher FSH (8.4±3.49 U/L vs. 7.04±2.32 U/L; p=0.024), higher E2 (53.94±47.61 vs. 42.93±18.92 pg/ml; p=0.025) levels, while their AMH (2.88±2.62 vs. 3.6±1.69 ng/ml; p=0.0002) was lower. There were no differences in TSH levels (1.64±0.96 vs. 1.66±0.65 uIU/ml; p= 0.652) between the two groups, FT3 (2.63±0.58 vs. 2.98±0.55 pg/ml; p=0.002) was lower and FT4 (1.304±0.29 vs. 1.13±0.21 ng/dl; p=0.0002) was higher in the TAI positive group.
Egg cell counts (6.0±3.82 vs. 7.5±3.95; p=0.015), clinical pregnancy rate (36.04 % vs. 69.56 %; p<0.001), live birth rate (23.25 % vs. 60.86 %) were lower, the miscarriage rate (35.48 % vs. 12.5 %; p=0.024) was higher in the TAI positive group. There was no difference in ICSI fertilization rate (69.12 % vs 62.91 %, p=0,12), although the fertilization rate was lower for patients under 35 in the TAI positive group, after adjusting for age.
Conclusion: TAI positive women carry a multitude of endocrine and metabolic parameters which may contribute to unfavorable effects on reproductive health.
Determination of the Optimal Elliptical Trajectories Around the Earth and Moon
Authors: Carter Thomas , Humi Mayer 
Published: August 2023

Abstract
Current space exploration programs call for the establishment of a permanent Human presence on the Moon. This paper considers periodic orbits of a shuttle between the Earth and the Moon. Such a shuttle will be needed to bring supplies to the Moon outpost and carry back those resources that are in short supply on Earth. To keep this shuttle in permanent periodic orbit it must have a thruster that forces it into an elliptical orbit from perigee near Earth to an apogee just beyond the Moon and back to perigee. The impacts of the Earth, Moon and Sun gravity on this orbit are considered. For this model we determine the eccentricity that minimizes the thrust requirements and the lunar ∆ υ requirements. We show that optimal placements of the eccentricity of the shuttle orbit can produce significant improvement in thrust (and fuel) requirements.
Zero Knowledge and Oblivious Ads Recommendation
Authors: Rajagopalan Anirudh , Singh Kunwar , Jayashrri Balaji , John Anu E 
Published: August 2023

Abstract
Interest-based Advertising, sometimes called online behavioural advertising, uses data collected from online activity on a digital device (e.g. smart phone, tablet, computer, etc.) using cookies, pixel tags, and other technologies to show personalized ads. While interest-based advertising is invaluable in helping advertisers reach the most suitable audience for their products, user privacy could be better protected if it could be accomplished without collecting a particular individual’s browsing history. This paper aims to implement an amalgamation of cryptography techniques that leverage zero-knowledge proof (ZKP) cryptography and oblivious transfer (OT) alongside standard hashing and fuzzy logic to ensure that users’ sensitive, personal and private data is always kept secure.
Pseudomonas putida as saviour for troubled Synechococcus elongatus in a synthetic co-culture – Interaction studies based on a multi-OMICs approach
Authors: Pflueger-Grau Katharina , Kratzl Franziska , Urban Marlene , Pandhal Jagroop , Shi Mengxun , Kleigrewe Karin , Meng Chen , Kremling Andreas 
Published: August 2023

Abstract
In their natural environments, microbes rarely exist in isolation; instead, they thrive in consortia where diverse interactions take place. In this study, a defined synthetic co-culture of the cyanobacterium S. elongatus cscB, which feeds the heterotrophic P. putida cscRABY with sucrose, was investigated to identify potential interactions. In initial experiments, a remarkable growth-promoting effect brought about by the presence of the heterotrophic partner on the cyanobacterium was observed, leading to a growth rate increase of up to 80% and increased photosynthetic capacity. Vice versa, the cyanobacterium had a neutral effect on P. putida cscRABY, highlighting the resilience against stress of pseudomonads and their potential as co-culture partners. A suitable reference process reinforcing the growth-promoting effect was established in a parallel operating photobioreactor system, which sets the basis for the analysis of the co-culture at transcriptional, proteomic, and metabolomic level. This multi-OMICs approach revealed several moderate changes, including alterations in the metabolism, transportation, and stress response in both microbes, indicating multi-level interactions. These findings provide valuable insights into the complex dynamics within the co-culture system, suggesting the exchange of further molecules beyond the unidirectional feeding with sucrose.
Targeting the Warburg Effect with Glucosodiene: A Case Report of a 43-year-old Female after Mastectomy of the right breast and axillary clearance with Successful First Case Treatment for Metastatic Triple Negative Breast Cancer (TNBC) of Bone.
Authors: ahmed Amr 
Published: August 2023

Abstract
Breast cancer is the most common type of cancer among women, and triple-negative breast cancer (TNBC) is a particularly aggressive subtype, representing 15-20% of cases. TNBC lacks estrogen, progesterone, and HER2 receptors, making it challenging to treat. This study explores a novel approach by investigating the metabolic pathways in TNBC, focusing on the alkaline glucose isomer, glucosodiene, as a potential therapy. The Warburg effect, discovered in 1924, serves as the basis for this investigation. The case report presents a 42-year-old female patient with TNBC Patient with MRM, Modified radical mastectomy, With axillary clearance., exhibiting a right breast lump with lymph node metastasis. Diagnostic tests confirmed invasive ductal carcinoma GII with negative hormone receptors and HER2/neu. The patient had previously undergone unsuccessful traditional chemotherapy and presented with bone metastasis. Treatment with glucosodiene for 15 days resulted in normal vital functions and no signs of cellular activity. This case study aims to evaluate an individualized treatment plan for TNBC patients and establish effective follow-up protocols. The trial is registered under clinicaltrials.gov number NCT05957939
Comprehensive evaluation of the effect of regional groundwater overexploitation restoration
Authors: Ling Minhua , Chen Jiangyu , Liu Fei , Yu Lili , Li Fengkai , Xia Qinyuan 
Published: August 2023

Abstract

The traditional groundwater overexploitation restoration only considers the impact on groundwater, on the basis of which, this paper also comprehensively considers the impact on economic society and the ecological environment. Based on analyzing the effect of groundwater overexploitation restoration on the groundwater–economic society–ecological environment (GESEE) system, an evaluation indicator system covering the GESEE system was constructed, an evaluation method for the effect of groundwater overexploitation restoration was established, and the effects were evaluated for Hebei Province, China, from 2014 to 2019. The results showed that the effect of groundwater overexploitation restoration in Hebei Province was obvious, and the grade of the groundwater overexploitation restoration effect improved from fair to good. The grade of the groundwater overexploitation restoration effect in most cities was improved to good. The measures that most affected the effect of groundwater overexploitation restoration in Hebei Province are strict control of extraction and reduction of consumption, while measures such as the replacement of water sources also play a significant role. An evaluation indicator system constructed in this paper can help to promote sophisticated effect evaluation of groundwater overexploitation restoration and improve the understanding and management of groundwater overexploitation restoration.
Surveillance of Naegleria fowleri in Louisiana's public water systems
Authors: Ward Lauren , Sherchan Samendra P. 
Published: August 2023

Abstract

The free-living amoeba Naegleria fowleri (Nf) inhabits soil and natural waters worldwide: it is thermophilic and thrives at temperatures up to 45 °C and in a multitude of environments. Three deaths in Louisiana were attributed to primary amoebic meningoencephalitis (PAM) caused by Nf infection in 2011 and 2013. Following these incidents, public water systems are now monitored for the presence of Nf in Louisiana. From 2014 to 2018, 29% (27/93) of samples collected showed positive for Nf and 68% (63/93) showed all thermophilic amoeba culture. Ten raw water sources and 17 distribution water systems tested positive. The year 2017 showed the highest number of samples with Nf (n = 10) followed by nine samples in 2015. As climate change increases surface water temperatures, continued testing for Nf prevalence will be an important facet of water monitoring and will need to extend into locations farther north than the current most common range.
N-unsubstituted Imidazoles: Design, Synthesis, and Antimicrobial Evaluation
Authors: Davood Asghar , EbrahimiNassimi Yassamin , Sardari Soroush , Farahani Yekta Farmahini 
Published: August 2023

Background:
All the current antifungal azoles have one substituted nitrogen atom in their imidazole
or triazole rings. In this study, eleven imine and amine derivatives of imidazole, in which both nitrogen atoms
of the imidazole ring are unsubstituted, were designed and synthesized.

Materials and Methods:
Imine derivatives were prepared by condensation of imidazole-4-carboxaldehyde with
appropriate amines, and then in the next step, using sodium borohydride, the imines were reduced to amine derivatives.
Docking studies reveal unsubstituted nitrogen atom of the imidazole ring coordinated well with the
heme molecule of the receptor. In vitro, antimicrobial evaluation was tested on Candida albicans, E. coli, and
Staphylococcus aureus.

Results:
Based on the results of the antimicrobial study, compound 10, which contains 4-chlorobenzyl moiety,
proved to be the most potent compound against Candida albicans, and it was more active than the reference
drug fluconazole and showed comparable activity to amphotericin B. Compounds 10 and 11 and compounds 8,
10 and 11 showed significant responses against E. coli and Staphylococcus aureus respectively.

Conclusion:
It is concluded that compound 10 can be acted as a new lead compound to find new azoles antifungal.
Revolutionizing Pharmaceutical Industry: The Radical Impact of Artificial
Intelligence and Machine Learning
Authors: Chhina Aashveen , Trehan Karan , Saini Muskaan , Thakur Shubham , Kaur Manjot , Shahtaghi Navid Reza , Shivgotra Riya , Soni Bindu , Modi Anuj , Bakrey Hossamaldeen , Jain Subheet Kumar 
Published: August 2023

Abstract:
This article explores the significant impact of artificial intelligence (AI) and machine learning (ML)
on the pharmaceutical industry, which has transformed the drug development process. AI and ML technologies
provide powerful tools for analysis, decision-making, and prediction by simplifying complex procedures from
drug design to formulation design. These techniques could potentially speed up the development of better medications
and drug development processes, improving the lives of millions of people. However, the use of these
techniques requires trained personnel and human surveillance for AI to function effectively, if not there is a possibility
of errors like security breaches of personal data and bias can also occur. Thus, the present review article
discusses the transformative power of AI and ML in the pharmaceutical industry and provides insights into the
future of drug development and patient care.
Impact of Phytomolecules with Nanotechnology on the Treatment of
Inflammation
Authors: Singh Sonia , Semwal Bhupesh C , Sharma Himanshu , Sharma Divya 
Published: August 2023

Abstract:
Inflammation is a part of the biological response of body tissues against harmful stimuli,
such as damaged cells, pathogens, irradiations, and toxic compounds. Numerous treatments, including
anti-inflammatory drugs that treat the condition of inflammation, are available for its management.
Because of the severe adverse effects associated with synthetic medications, phytotherapy
may be a promising and effective approach to treating inflammation. The therapeutic potential of
herbs is due to their capacity to target a variety of inflammatory mediators, including chemokines,
cytokines, nitric oxide, lipoxygenase, nuclear factor kappa-B, and arachidonic acid. Furthermore,
nanomedicine may be a valuable and effective formulation approach for overcoming the drawbacks
of phytoconstituents, such as their low bioavailability, high first-pass metabolism, and poor stability.
The current manuscript provides a thorough description of many phytoconstituents and herbal
plants that have great potential for treating inflammation-related diseases, as well as information on
their limitations, drug formulations, and regulatory issues.
Natural Antioxidant Extracts as Anti-browning Agents from Algerian
Date Palm Fruit
Authors: Wafa Bensania , Amar Djeridane , Noureddine Bouras , Mohamed Yousfi 
Published: August 2023

Abstract:
Enzymatic browning is a negative change that affects fruits and vegetables. This makes them
unfit for consumption or reduces their shelf life and quality. This reaction alters the appearance, texture,
fragrance, taste, and nutritional value of the food. In order for these products to be widely accepted by
consumers, it is necessary to use natural compounds with anti-browning properties.

Objective:
The main objective of this study was to select effective extracts for the anti-browning (antipolyphenol
oxidase and anti-peroxidase), and antioxidant activities of by-products of Phoenix dactylifera
L., Ghars variety, from Algeria.

Methods:
Hydro-methanolic extracts from the pedicel, perianth, and leaves of date palm were examined
to evaluate the phenol and total flavonoid contents. Using spectrophotometric techniques, the antioxidant
activities were assessed using 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH●), 2, 2’-azino-bis-(3-
ethylbenzthiazoline-6-sulfonic acid) radical (ABTS●+) and Ferric Reducing Antioxidant Power (FRAP)
assay, examined the enzyme inhibitory activity against polyphenol oxidase and peroxidase of Phoenix
dactylifera L. extract.

Results:
The range of total phenolic and flavonoid contents was 12.29 to 48.98 mg gallic acid equivalent/
g dry matter and 2.83 to 15.07 mg rutin equivalent/g dry matter, respectively. The pedicel extracts
showed significant antioxidant activity in the DPPH and FRAP tests (IC50 = 0.0057 ± 0.0010 mg/ml and
FEAC = 1.1961 ± 0.0647) compared to other extracts. However, in the ABTS assay, the leaf extract exhibited
an interesting potency (IC50 = 0.0020 ± 0.0001mg/ml). The study on the anti-browning activity
of date palm by-product extracts showed that it inhibited the activity of peroxidase enzyme from date
palm fruit.

Conclusion:
This work is the first time the potential of an extract from date palm by-products to enzymatically
reduce the browning of date palms is presented. According to the results obtained, the different
organs studied from the Ghars date palm, are a powerful natural antioxidant and may include natural
compounds that retard browning by enzymes.
News of Death In Jumlah Fi‘liyyah In Obituarial Rubric Of Al-Ahrām Newspaper December 2017 – March 2018 Edition: Semantic Analysis
Authors: Farhani Nada 
Published: August 2023

This study discusses news of death in the jumlah fi‘liyyah in the obituary rubric of Al-Ahrām (SKA) newspaper with the euphemisms contained there in. This study aims to reveal the fi'l form used and the choice of words or euphemisms in obituaries jumlah fi‘liyyah numbers in the opening sentences of the SKA obituary rubric, December 2017 – March 2018 edition. The theory used in this research is semantic. The data of this research is in the form of obituaries in jumlah fi‘liyyah in the opening sentence of the SKA obituary rubric advertisement. The method used in providing data is the listening method, with basic tapping and orthographic note-taking techniques as advanced techniques. At the data analysis stage, the method used is the distribution method with basic techniques for natural elements and advanced courses in the form of dissipation techniques and replacement techniques. As for the data presentation stage, the informal presentation method is used.
Based on research conducted on obituaries in jumlah fi‘liyyah in the opening sentence of the SKA obituary rubric advertisement, eight variations of obituaries used based on the fi'l were found. The eight obituaries in jumlah fi‘liyyah are divided into three categories of fi'l forms, namely fi'l mujarrad ma'lūm, fi'l mazīd ma'lūm, and fi'l mazīd majhūl. The eight fi'ls in these three forms are euphemisms to replace /māta/ in BA. Thus, it is known that the perspective of the Arab nation in symbolizing someone's death with the choice of subtle words in the form of certain fi'l and visible religious symbols through the terms used.
Desain Pengabdian Pembinaan Mudabbir-Mudabbirah dalam Pengasuhan Santri dengan Pendekatan Mau’idhah Hasanah pada Dayah Boarding School
Authors: Hayati Salma , Lailatussaadah  , Mujiburrahman  , Yusriman  , Nisak Amiratun , An-Nazary Nargis 
Published: August 2023

The purpose of this service-based research is to design the mentoring of mudabbir-mudabbirah in the care of santri with a mau'idhah hasanah approach in dayah of boarding school. The research method used is research and development based on Sugiyono which refers to the theory of Borg and Gall and takes three (3) steps; potential and problems, data collection and activity design. The data were analyzed in a qualitative descriptive. The results of the service-based research of mudabbir mudabbirah mentoring in nurturing santri with mau'idhah hasanah were carried out using a five-stage frame of reference; input, activities, output, purpose and goal.
Kualitas Fisik Dan Organoleptik Daging Ayam Broiler Yang Diberi Ransum Berbasis Pakan Lokal Berprobiotik
Authors: Prayoga Arya Hangga , Hendalia Ella , Noferdiman Noferdiman 
Published: August 2023

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pakan lokal berprobiotik terhadap kualitas fisik dan kualitas organoleptic daging ayam broiler. Penelitian ini dilaksanakan di Farm Fakultas Peternakan, Universitas Jambi. Pengujian kualitas fisik dan kualitas organoleptik dilaksanakan di Laboratorium Fakultas Peternakan Universitas Jambi. Sebanyak 200 ekor DOC strain platinum dimasukkan secara acak ke dalam 20 kandang, terdiri atas 5 perlakuan dan 4 ulangan. Pakan Perlakuan yang diterapkan adalah P0 (100% P-kom +0 % P-pro), P1 (75% P-kom + 25% P-pro), P2 (50% P-kom + 50% P-pro), P3 (25% P-kom + 75% P-pro) dan P4 (0% P-kom + 100% P-pro). Pakan diberikan ad libitum selama 35 hari. Pada hari ke 35 dilakukan pemotongan ayam dan pengambilan sampel dagi dada. Parameter yang diamati adalah kualitas fisik (Daya Ikat Air, susut masak, dan pH) dan organoleptik (warna, rasa, tekstur dan aroma) DAGING. Data kualitas fisik dianalisis dengan sidik ragam (ANOVA), sedangkan kualitas organoleptik dianalisis dengan uji Hedonic Kruskal-Wallis. Hasil penelitian menunjukkan bahwa pemberian ransum berbasis pakan lokal berprobiotik memberikan pengaruh tidak nyata (P > 0,05) terhadap kualitas fisik dan organoleptic daging ayam broiler. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa daging ayam broiler yang diberi ransum berbasis pakan lokal berprobiotik memiliki kualitas fisik dan organoleptik yang relative sama dengan daging ayam broiler yang diberikan pakan komersil dan dapat diterima dengan baik oleh konsumen.
Kata kunci : Daging ayam broiler,pakan local berprobiotik,,kualitas fisik,,kualitas organoleptic