bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ekspresi VEGF di Jaringan Hati Tikus Pasca Induksi 2AAF/CCl4
Authors: Liem Isabella Kurnia , Alvarabie Radietya , Oktorina Fanny , Husna Firda Asma'ul , Wuyung Puspita Eka , Kodariah Ria 
Published: June 2023

Vascular Endothelial Growth Factor (VEGF) merupakan sebuah faktor angiogenik poten yang terpicu ekspresinya jika jaringan hati mengalami cedera. Pada cedera hati kronis, VEGF diduga dapat berperan sebagai faktor pro-fibrotik atau anti-fibrotik. Penelitian ini dilakukan untuk mengetahui peningkatan ekspresi VEGF di jaringan hati tikus model dengan cedera hati kronis 2AAF/CCl4 (2-acetylaminofluorene dan carbon tetrachloride). Penelitian menggunakan desain eksperimental dan dilakukan sejak Oktober 2019- April 2021 di laboratorium Patologi Anatomi dan Departemen Anatomi Fakultas Kedokteran Universitas Indonesia. Dua belas ekor tikus Wistar dibagi menjadi dua kelompok, yaitu kelompok kontrol (normal; n=6) dan kelompok perlakuan (diinduksi dengan 2AAF/CCl4; n=6). Dilakukan pemeriksaan morfologi hati dengan pewarnaan hematoxylin eosin dan Masson’s trichrome dengan skoring NAFLD activity score (NAS) dan pengukuran kadar VEGF menggunakan pewarnaan imunohistokimia. Semua tikus kelompok perlakuan mengalami kerusakan hati dan fibrosis, dengan kerusakan hati terbanyak mencapai derajat 5 (5 dari 6) dan fibrosis hati terbanyak mencapai derajat 2 (4 dari 6). Sedangkan pada kelompok kontrol, semua tikus menunjukkan morfologi hati dalam kondisi normal (derajat 0). Skor ekspresi VEGF pada kelompok perlakuan (median [min-max] = (115 [97-141]) tidak meningkat bermakna (uji Mann-Whitney U; p=0,688) dibandingkan kelompok kontrol (112 [94-129]). Disimpulkan bahwa pada jaringan hati tikus model cedera hati yang diinduksi oleh 2AAF/CCl4 terdapat peningkatan VEGF namun tidak bermakna secara statistik.
Problem Based Learning Oriented Thematic Worksheets: Increased Discipline of Elementary School Students
Authors: Nugraheni Wahyu Nur , Sutama  
Published: June 2023

Learning activities in elementary schools are carried out by paying attention to all aspects that need to be nurtured and developed properly. Learning activities must cover three domains, namely affective, cognitive, and psychomotor. The teacher's patterns and strategies in implementing the concept understanding process are important points in delivering learning. Worksheets is certainly a process for students to seek further understanding of the concepts presented by the teacher. This study aims to analyze the effect of problem-based learning-oriented thematic worksheets on discipline character of elementary school students. This research method is quasi-experimental on the fourth grade students. The data analysis applied, namely the t-test, is one of the parametric statistical tests with two measurements. In implementing the problem-based learning-oriented thematic worksheets, there are several stages, namely introduction to the teacher, pre-test implementation, introduction to students, post-test implementation, and processing data with validity and reliability tests. By getting the results the average pre test shows 3.125 and the average post test shows 3.575. From these results, there is an increase in discipline in working on worksheets.
KETAHANAN PANGAN ANGGOTA DAN NONANGGOTA KWT MEKAR JAYA PENERIMA PROGRAM PEKARANGAN PANGAN LESTARI SELAMA PANDEMI COVID-19
Authors: Setiawan Rendi , Indriani Yaktiworo , Riantini Maya 
Published: June 2023

Goals of this study is to analyze food security and factors influencing food security of members and nonmembers of KWT Mekar Jaya, the recipient of the sustainable food yard program (P2L). This study was conducted purposively in Giri Tunggal Village of Pagelaran Utara Subdistrict of Pringsewu Regency. There were 60 household samples consisting of 30 members and 30 nonmembers of KWT Mekar Jaya. The main and second data of this research was collected in April-July 2021. The first aim was analyzed by crosstabs between the part of food expenditure and sufficiency of energy and the second goal was analyzed by logistic regression. The results of this study showed that most respondents (65%) are classified as food resistant, and the rest (35%) are classified as vulnerable to food. The factors that influenced the household food security were the number of family members and household income. Key words: food security, household, KWT Mekar Jaya, P2L
ANALISIS KINERJA DAN STRATEGI PENGEMBANGAN KOPERASI PERTANIAN SEANDANAN KABUPATEN PESAWARAN
Authors: Mubarok Muhammad Rizqi , Lestari Dyah Aring Hepiana , Sayekti Wuryaningsih Dwi 
Published: June 2023

This research aims to analyze the cooperative performance, internal and external environment, and formulate the development strategies of Agriculture Cooperative Seandanan. This research is taken at Agriculture Cooperative Seandanan in Pesawaran District, which is chosen purposively. Furthermore, data of this research was collected in January 2019. This research uses a case study method. Respondents of this research are 13 people consist of administrators and members of cooperative, experts and regulators. Data analysis methods used in this research are qualitative descriptive analysis, SWOT (Strengths, Weakness, Opportunities, and Threats) analysis, and Quantitative Strategic Planning Matrix (QSPM). The results of this research showed that the performance of cooperative was included in the category of sufficient quality. Internally, the cooperatives had the main strength that healthy and independent capital and finance, while the main weakness that was management function that were not managed optimally. Externally, cooperative’s main opportunity was easy and fast loan procedures, although the main threat was the weak understanding of the community about cooperatives. The priority strategies for developing cooperatives were maximizing the cooperative management functions to strengthen the cooperative image in the community, utilizing assets in the form of buildings to increase cooperative income, in addition to compiling and completing the unorganized administration of cooperatives and formulating a clear vision and mission. Key words: agriculture cooperative, QSPM, SWOT analysis
Kajian Literatur Dampak dan Pengaruh Digital Influencer Marketing terhadap Perkembangan Strategi Bisnis
Authors: Wirapraja Alexander , Hariyanti Novi Tri , Aribowo Handy 
Published: June 2023

Abstrak. Media sosial menghubungkan individu di seluruh dunia, di mana kekuatan interaksi dan berbagi informasi telah bergeser dari perusahaan menjadi berorientasi pada kebutuhan pelanggan. Peran influencer khususnya pada saluran pemasaran digital seperti media sosial telah digunakan sebagai solusi untuk memengaruhi tingkat keputusan pembelian konsumen dan dengan meningkatkan tingkat pembelian terhadap produk dan layanan yang dipasarkan. Pada penelitian ini menggunakan metode studi literatur untuk menemukan dampak pemanfaatan influencer pada media sosial, kelebihan dan kekurangan menggunakan jasa influencer dan faktor-faktor apa saja yang mendorong organisasi pada era moderen saat ini wajib menggunakan influencer sebagai bagian dari strategi pemasaran mereka. hasil akhir yang didapatkan adalah adanya gambaran secara luas mengenai peran influencer sehingga dapat menjadi masukan bagi organisasi bisnis dalam mengembangkan strategi pemasaran mereka.

Abstract. Social media connects individuals around the world, where the power of interaction and information sharing has shifted from corporate to customer oriented. The role of influencers especially in digital marketing channels such as social media has been used as a solution to influence the level of consumer purchasing decisions and by increasing the level of purchase of products and services being marketed. This research uses the literature study method to find the impact of using influencers on social media, the advantages, and disadvantages of using influencer services and what factors encourage organizations in the modern era to use influencers as part of their marketing strategy. The result obtained is a broad description of the influencer's role so that it can become input for business organizations in developing their marketing strategy.
Social Media Content And Hedonic Brand Image In Eco-Friendly Fashion Start-Up
Authors: Tulipa Diyah , Sulistyo Andy Pratama , Mellifan Tania 
Published: June 2023

In the internet era, as it is today, social media is an important tool for communication. Not only for personally but also for communication between companies and consumers. The study aims to determine the effect of social media advertising content and sales promotional content on purchase intention through the hedonic brand image of brand- new fashion start-up KA2N. This study employed 113 Instagram followers of KA2N. The results show that social media advertising content and media social sales promotional content have influence hedonic brand image, then in turn hedonic brand image affects purchase intention. However, social media advertising content and social media sales promotion content does not directly influence consumer purchase intention, significantly. It means that hedonic brand image mediates the relationship between social media advertising content and social media sales promotion content with purchase intention.
ANALISIS MINAT MASYARAKAT USIA MUDA TERHADAP WISATA SUSUR SUNGAI DAN WISATA PERMUKIMAN KUMUH DI CI LIWUNG BIDARA CINA – MANGGARAI
Authors: Ulum Miftahul , Handawati Rayuna , Hijrawadi Sony Nugratama 
Published: June 2023

Abstract : Wisata sungai menjadi salah satu upaya pemulihan sungai yang dilakukan oleh beberapa negara. Ci Liwung yang merupakan sungai paling tercemar di Provinsi DKI Jakarta dan menjadi salah satu tempat pembuangan (water back landscape), nyatanya memiliki potensi wisata yaitu wisata susur sungai dan wisata permukiman kumuh. Penelitian ini menggunakan pendekatan kuantitatif dengan penyebaran kuesioner dan analisis deskriptif. Hasil penelitian menunjukkan bahwa masyarakat usia muda memiliki minat yang rendah yaitu sebesar 59,3%. Berdasarkan indikator pengukur minat yaitu minat transaksional, minat referensial, dan minat preferensial termasuk kedalam kategori rendah, sedangkan minat eksploratif termasuk kedalam kategori tinggi. Dilihat berdasarkan komponen pariwisata, amenitas wisata yang belum memadai baik secara kualitas mau kuntitas, atraksi wisata yang berbeda dan aksesibilitas yaitu jarak lokasi tempat tinggal dengan lokasi wisata menjadi penyebab rendahnya minat masyarakat usia muda terhadap wisata susur sungai dan wisata permukiman kumuh di Ci Liwung Bidara Cina – Manggarai.
Kata Kunci: Minat, Masyarakat Usia Muda, Wisata Susur Sungai, Wisata Permukiman Kumuh
Financial Management Training As An Effort To Improve The Reliability Of Preparation Of Financial Statements
Authors: Khamisah Nur , Hakiki Arista , Nida Rahma , Yusrianti Hasni , Sitepu Christian Damar Sagara 
Published: June 2023

Financial Statement is one of very important element in business, because it is an output that can give information for user as base for taking decision. The problems faced cooperative employees of PT PUSRI Palembang are, they not yet understand about financial management in compile report effective and efficient finance. Financial management need understood for cooperative manager, because its related with the reliability of information in financial statement cooperative . This community service activity aims to provide knowledge and skills regarding financial management in order to increase the reliability of financial statement to the target group, namely the PT PUSRI Palembang employee cooperative. Activity devotion done with method outreach and training . Benefit from activity devotion to employees cooperative PT PUSRI Palembang is expected become useful input for participants activity capable to manage financial in a effective and efficient manner so the cooperative objective can optimally achieved. Besides it, with knowledge management good finances owned by the participants can used as consideration in taking decision related finance nor direction policy business in a manner more broad .
TINJAUAN YURIDIS TERHADAP PEMENUHAN HAK BAGI TENAGA KERJA DISABILITAS MENURUT HUKUM POSITIF DI INDONESIA
Authors: Dharma Putra Sigalo , Asyhadie H. Zaeni 
Published: June 2023

Sebagian besar penyandang disabilitas tidak memiliki kehidupan yang layak karena tidak memiliki kesempatan untuk bekerja. Kenyataan ini kontradiktif dengan ketentuan Undang-Undang Nomor 8 Tahun 2016 tentang Penyandang Disabilitas yang menyatakan bahwa penyandang disabilitas berhak atas kesempatan dan perlakuan yang sama untuk bekerja sesuai dengan Janis dan tingkat kecacatan, Pendidikan dan kemampuannya. Permasalahannya, ketentuan mengenai tenaga kerja penyandang disabilitas ini tidak diatur dalam undang-undang induk Ketenagakerjaan yaitu Undang-Undang Nomor 13 Tahun 2003 tentang Ketenagakerjaan. Adapun jenis penelitian yang digunakan adalah penelitian hukum normatif dengan menggunakan Pendekatan Undang-Undang (Statute Approach) dan Pendekatan Konsepsual (Conceptual Approach). Dan dapat disimpulkan bahwa telah terjadi ketidaksinkronan antar peraturan perundang-undangan dan kekosongan hukum mengenai hak bekerja bagi tenaga kerja penyandang disabilitas pada Undang-Undang Ketenagakerjaan.
KAJIAN YURIDIS PENGADAAN TANAH BAGI KEPENTINGAN UMUM PASCA BERLAKUNYA UNDANG-UNDANG NOMOR 11 TAHUN 2020 TENTANG CIPTA KERJA
Authors: Mindan Cahyani Cici , Rahman Arief 
Published: June 2023

Penelitian ini bertujuan untuk mengetahui bagaimana pengaturan dan mekanisme pengadaan tanah untuk kepentingan umum pasca disahkannya Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja serta bagaimana perlindungan hukum terhadap masyarakat pemegang hak atas tanah. Penelitian ini merupakan penelitian hukum normatif dengan menggunakan pendekatan perundang-undangan, pendekatan konseptual, dan pendekatan historis.Hasil penelitianmenunjukan bahwa revisi beberapa pasal yang berkaitan dengan pengadaan tanah dalam Undang-Undang Cipta Kerja mempermudah proses pengadaan tanah terutama yang berkaitan dengan proyek strategis nasional. Namun, meski memberi kemudahan dalam pengadaan tanah, perubahan tersebut juga dipandang memiliki dampak negatif, yaitu dapat mengakibatkan kerusakan lingkungan dan konflik agraria.
PERLINDUNGAN HUKUM DALAM PERKAWINAN DI BAWAH UMUR PADA TRADISI MERARIK SUKU SASAK
Authors: Devi Wulandari Fitria , Salat Musakir 
Published: June 2023

Penelitian ini bertujuan untuk mengetahui bentuk perlindungan hukum dalam perkawinan di bawah umur pada tradisi merarik di Kabupaten Lombok Timur. Penelitian ini adalah penelitian hukum normatif-empiris dengan menggunakan pendekatan perundang-undangan, pendekatan konseptual, pendekatan kasus dan pendekatan sosiologis, hasil penelitian terungkap bahwa bentuk perlindungan hukum dalam perkawinan di bawah umur pada tradisi merarik adalah pemberian dispenasi nikah namun tidak semua kasus tradisi merarik diberikan dispensasi nikah oleh Pengadilan Agama Selong. Ada beberapa pertimbangan hakim untuk memutuskan apakah layak atau tidak diberikan dispensasi nikah dan dasar hukum yang digunakan hakim Pengadilan Agama Selong dalam menentukan dispensasi nikah adalah pasal 7 ayat (2) undang-undang perkawinan. Adapun faktor yang menjadi hambatan dalam pelaksanaan pemberian dispensasi nikah adalah dokumen yang tidak lengkap, ketidaktauan masyarakat terhadap hukum positif dan faktor usia yang masih jauh dari ketentuan undang-undang perkawinan.
ANALISIS PUTUSAN NO. 17/Pdt.G.S/2020/PN.Sel TENTANG GUGATAN SEDERHANA MENGENAI WANPRESTASI DALAM PENGADAAN PANGAN ANTARA SUPLAYER BANTUAN PANGAN NON TUNAI (BPNT) DENGAN AGEN/E-WARONG
Authors: Havia Nidaan , Kusuma Rahmawati 
Published: June 2023

Penelitian ini bertujuan untuk mengetahui pertimbangan hakim mengenai Putusan 17/Pdt.G.S/2020/PN.Sel tentang gugatan sederhana mengenai wanprestasi dalam pengadaan pangan antara suplayer bahan pangan BPNT dengan Agen/E-Warong dan untuk mengetahui akibat hukum terhadap pelaksanaan adanya putusan No. 17/Pdt.G.S/2020/PN.Sel tentang gugatan sederhana mengenai wanprestasi dalam pengadaan pangan antara suplayer bahan pangan BPNT dengan Agen/E-Warong. Metode penelitian dalam penyusunan skripsi ini menggunakan metode normatif, dengan metode pendekatan perundang-undangan, pendekatan kasus, dan pendekatan konseptual. Hasil penelitian yang didapatkan dari penelitian ini yaitu pertimbangan hakim terhadap putusan tersebut dimana suplayer daging selanjutnya disebut sebagai pengguga mengajukan gugatan dalam bentuk Gugatan Sederhana, tetapi tidak memperhatikan Perma No. 4 Tahun 2019 perubahan atas Perma No. 2 Tahun 2015 tentang Tata Cara Penyelesaian Gugatan Sederhana, sehingga cacat di syarat formil. Selanjutnya akibat hukum yang timbul atas terjadinya sengketa ini dimana pihak penggugat yaitu Suplayer Daging tidak dapat lagi memasok bahan pangan kepada Agen/E-Warong di Kecamatan Pringgasela karena kontrak Kerjasama yang otomatis terputus.
Search Algorithms for a System of Different Representatives of Subsets of a Finite Set
Authors: Terzi Dmitri 
Published: June 2023

The paper considers various aspects and approaches regarding the search for a system of differenrt representatives (SDR) of subsets of a finite set. Algorithm 3 has been developed, which is an algorithmization of the search process for SDR on the basis of Hall's theorem on the existence of SDR. Algorithms 1-5 for searching for partial and complete SDRs based on the technology for solving problems of the transport type, in particular, the algorithm associated with the construction of cycles, are given. SDR search algorithms can be used as auxiliary tools for solving combinatorial problems. It is also shown, conversely, that the search for SDR can be considered as a combinatorial optimization problem.
Mathematics Subject Classification – MSC2020: 90-08, 90B06, 90C27
Studi Pemeriksaan Sedimen Urine berdasarkan Karakteristik Pada Penikmat Kopi di Asrama Kiwal Brawijaya Surabaya
Authors: Wiliyanarti Pipit Festy , Atrasina Jilan , Maulidiyanti Ellies Tunjung Sari 
Published: June 2023

Coffee is a psychostimulant drink which can provide good benefits for the body if consumed in moderation. However, one of the effects in excessive coffee consumption over a long period of time that is not accompanied by adequate fluid intake is in fact able to affect sedimentation in urine. The caffeine content which has a lot of particles can cause the kidneys to be unable to reabsorb it. Therefore, it is excreted along with the urine and it causes the urine to be more concentrated. This causes increased sedimentation in the urine. The purpose determined the description of urine sediment examination on coffee connoisseurs in Asrama Kiwal in Brawijaya of Surabaya. The research type used descriptive research with a research sample of 40 people taken by purposive sampling. The results showed that the description of urine sediment examination on coffee connoisseurs at Asrama Kiwal in Brawijaya of Surabaya that 12 people (30%) had normal urine sediment and 28 people (70%) had abnormal urine sediment. Based on the characteristics of the respondents, the presence of abnormal urine sediment was found in the age category 30 years as many as 26 people (76%) with a frequency of coffee consumption > 3 times per day as many as 14 people (35%) in a series of coffee consumption for > 10 years as many as 27 people ( 67.5%) and the frequency of consumption of mineral water 2 litters per day as many as 24 people (60%). The conclusion of this study was that most of the coffee connoisseurs in Asrama Kiwal Brawijaya of Surabaya that experienced abnormal urine sedimentation.Keywords: Coffee, Urine Sediment
Formulasi Dan Karakteristik Fisik Sediaan Plester Hidrogel Ekstrak Daun Ciplukan (Physalis angulata L.) Dan Batang Kayu Manis (Cinnamomum burmannii)
Authors: Hanistya Ria , Samlan Karima 
Published: June 2023

Diabetes mellitus is a degenerative disease caused by the damage of beta pancreatic cells. This caused many complication such as diabetic ulcer which left untreated can cause an open wound hard to heal thereby reducing the quality of life. Treatment of diabetic ulcer despite using antidiabetic also using an antibiotic therapy like Mupirocin. In its development, the use of natural ingredients is known to be used as adjuvant therapy for diabetic ulcer such as Ciplukan leaves and Kayu Manis bark. Both of the plant contain phytochemical compound like sinamaldehid, tannin, polyphenol and flavonoid which can work as wound healer. To increase its efficacy then Ciplukan leaves and Kayu Manis bark were formulated as hydrogel patch. Hydrogel patch are known has advantages like better penetration, hygienic and easy to administered Ciplukan (Physalis angulata L.) leaves and Kayu Manis (Cinnamomum burmannii) Bark extracted with maceration technique. The extracts then made into matrix type hydrogel patch with 10% HPMC and 5% PVA as backing patch. The backing patch and extract then placed on a square cast and dried under room temperature for 24 hours. The hydrogel patch then evaluated for physical characteristic including organoleptic aspect, weight uniformity, moisture content and pH. The results showed that Ciplukan leaves and Kayu Manis Bark hydrogel patch have a semi solid consistency, transparent greenish color and distinctive smell. The average pH is 5,5 and have average weight around 1,18 grams. The moisture contens of hydrogel patch is 2,42%. The Ciplukan leaves and Kayu Manis bark is able to formulated into hydrogel patch. The hydrogel patch is showing good appearance and having good properties as topical dosage form. The pH of the hydrogel patch is suitable with pH of the skin and have no intention to irritate the skin. Hydrogel patch also giving a cooling sensations in wound area thus increase patients convenience and acceptability. Keywords: Diabetes mellitus, extract, drug delivery system, hydrogel patch, adjuvant therapy
Uji Efektifitas Perasan Jahe (Zingiber officinale) Terhadap Pertumbuhan Jamur Candida albicans
Authors: Azizah Fitrotin , Artanti Dita 
Published: June 2023

Candidiasis is one of the most common infectious diseases caused by Candida sp. In 2017 the Mycology Division of Dr. Soetomo said there were 67 patients diagnosed with candidiasis. The use of natural ingredients as an alternative to traditional medicine is increasing because it is safe for consumption and does not cause side effects. One of the natural ingredients is Ginger (Zingiber officinale). The choice of using ginger juice (Zingiber officinale) is because the ingredients are easy to obtain and easy to apply by the community. This study aims to determine the antifungal effectiveness of ginger (Zingiber officinale) juice against the growth of Candida albicans. This research is experimental by doing the treatment which was repeated 4 times, namely the concentration of ginger juice 20%, 40%, 60%, 80%, 100%, negative control (aquadest) and positive control (ketoconazole). The inhibition zone examination method used the Kirby Bauer diffusion method which was characterized by the formation of a clear zone around the paper disc on MHA (Muller Hinton Agar) media. The inhibition zone formed was measured using a caliper, then the data obtained were analyzed using the Mann-Whitney test. From laboratory examination, it was found that the average diameter of inhibition formed with concentrations of 20%, 40%, 60%, 80%, and 100% was 0 mm, and the negative control (aquadest) was 0 mm. The results of statistical analysis showed that 0.05 obtained a significant value between the administration of juice concentrations of 20%, 40%, 60%, 80%, 100% and not given (negative control-aquadest) = 1,000. From these results, it was concluded that there was no significant difference between the concentrated juice of 20%, 40%, 60%, 80%, 100% and not given (negative control - distilled water)Keywords : Ginger (Zingiber officinale), Candida albicans