bluuebunny/crossref_metadata_2025_split huggingface dataset:
Noise exposure assessment of non-coal mining workers in four provinces of China
Authors: Wang Xin , Kang Ning , Dong Yiwen , Liu Kai , Ning Kang , Bian Hongying , Han Feng , Chen Yongqing , Ye Meng 
Published: January 2023

ObjectiveThis study aimed to understand the noise exposure of non-coal mines in China to take appropriate controls to protect workers' health.MethodsAn assessment of non-coal miners' noise exposures was conducted in four provinces in China. Individual noise exposure levels were measured, and the survey on the hearing protector device (HPD) equipment was administered.Results423 noise dosimeter measurements were obtained, including drilling, blasting, ore drawing, transportation, winching, crushing, screening and ball milling, and auxiliary (air pressure, pump, and maintenance). A total of 31.9% of the individual noise levels (LEX,8h) exceeded 85 dB(A), and the median dosages of non-coal miners with high noise exposure were: excavation workers-89.1 dB(A), mill operators-88.7 dB(A), and crusher operators-87.0 dB(A). The noise dose of underground mine workers is higher than that of surface mine workers (P &lt; 0.001). A total of 53.7% of non-coal mining enterprises are not equipped with HPD for workers, mainly small and micro enterprises.ConclusionsHigh levels of hazardous noise exposure are typical in non-coal mines. Noise exposure data can help to develop more feasible noise controls.
Patterns of improvement in functional ability and predictors of responders to dual-task exercise: A latent class analysis
Authors: Ho Vanda , Chan Yiong Huak , Merchant Reshma Aziz 
Published: January 2023

BackgroundExercise is the pillar for healthy aging. “Non-responders” may be due to a mismatch in exercise prescription. A latent cluster analysis (LCA) profile can be useful to uncover subpopulations sharing similar profiles or outcomes. We aim to use the LCA to develop a response prediction model for older adults who would benefit from The Healthy Aging Promotion Program for You, a community-embedded dual-task exercise program.MethodsA total of 197 participants completed the 3-month follow-up, and the complete data were available for 136 community-dwelling older adults. Inclusion criteria were age ≥60 years, pre-frail or frail and ambulant, mild cognitive impairment, and ability to provide consent. Data collected include demographics, education, falls, physical function (Katz ADL scale and Lawton's IADL scale), physical activity (rapid assessment of physical activity), cognition (Montreal Cognitive Assessment; MoCA), frailty (FRAIL scale), and perceived health, pain, anxiety/depression, fear of falling, and social isolation (Lubben Social Network Scale). The body mass index (BMI), handgrip strength, and short physical performance battery (SPPB) were measured. Those who improved in frailty, anxiety/depression, pain, Lubben, MoCA, SPPB, fear-of-falling, physical activity, falls, and HGS were classified as responders.ResultsThe mean age was 74.7 years, BMI 23.5 kg/m2, 23.5% were male, 96.3% were of Chinese ethnicity, 61% were pre-frail, education level of 4.3 years, and the MoCA score of 23.3 ± 4.8. Two clusters were identified: non-responders (61.8%) and responders (38.2%). Responders had significant improvement in cognition (44.2% vs. 0, p &lt; 0.001) and SPPB (gait:28.8% vs. 0, p &lt; 0.001; balance:42.3% vs. 15.5%, p = 0.001; chair-stand:65.4% vs. 4.8%, p &lt; 0.001). Responders were significantly older (76.9 vs. 73.3 years, p = 0.005), had higher BMI (24.8 vs. 22.8 kg/m2, p = 0.007), lower education (3.4 vs. 4.9 years, p = 0.021), lower MoCA scores (21.8 vs. 24.3, p = 0.002), and lower SPPB scores (8.7 vs. 10.6, p &lt; 0.001). The predictive variables for the responder cluster were age ≥75 years, BMI ≥23 kg/m2, robust, no anxiety, pain, fear of falling, MoCA ≤22, Lubben ≤12, SPPB score: chair-stand ≤2, balance ≤2, gait &gt;2, handgrip strength &lt;20 kg, no falls and RAPA &gt;3. With an optimal cut-off of ≥12, this prediction model had sensitivity of 76.9%, specificity of 70.2%, positive predictive value 61.5%, and negative predictive value of 83.1%.ConclusionResponse to dual-task exercise was influenced by age, SPPB, BMI, and cognition. Prospective longitudinal studies are needed to validate this LCA model and guide the development of public health strategies.
Influences of temperature and humidity on cardiovascular disease among adults 65 years and older in China
Authors: Chen Huashuai , Zhang Xuebin 
Published: January 2023

BackgroundThe burden of cardiovascular disease (CVD) on the current aging society in China is substantial. Climate change, including extreme temperatures and humidity, has a detrimental influence on health. However, epidemiological studies have been unable to fully identify the association between climate change and CVD among older adults. Therefore, we investigated the associations between temperature and relative humidity and CVD among older adults in China.MethodsWe used cohort data from the China Longitudinal Health and Longevity Survey (CLHLS) conducted in 2002, 2005, 2008, 2011, 2014, and 2018. A total of 39,278 Chinese adults 65 years and older participated in the analyses. The average annual temperatures and relative humidity during 2001 and 2017 (before the survey year) at the city level in China were used as the exposure measures. We selected patients with hypertension, heart disease, and stroke to create a sample of CVD patients. The associations between temperature and relative humidity and CVD were analyzed using the generalized estimation equation (GEE) model. Covariates included sociodemographic factors, health status, lifestyle, and cognitive function.ResultsThe average annual temperature was negatively correlated with the prevalence of CVD. Every 1°C increase in the average annual temperature reduced the rates of hypertension by 3% [odds ratio (OR): 0.97; 95% confidence interval (CI): 0.96–0.97], heart disease by 6% (OR: 0.94; 95% CI: 0.92–0.95), and stroke by 5% (OR: 0.95; 95% CI: 0.94–0.97). The results of the analyses stratified by sex, urban/rural residence, and educational level were robust. The average annual relative humidity was inversely associated with the likelihood of CVD among older adults. Every 1% increase in the average annual relative humidity reduced the rates of hypertension by 0.4% (OR: 0.996; 95% CI: 0.99–1.00), heart disease by 0.6% (OR: 0.994; 95% CI: 0.99–1.00), and stroke by 0.08% (OR: 0.992; 95% CI: 0.98–1.00). However, the effects were more obvious with higher humidity levels (&gt;70).ConclusionOur findings suggest that higher temperatures and relative humidity may reduce the risk of CVD among older adults.
Evaluation of health system resilience in 60 countries based on their responses to COVID-19
Authors: Zhao Laijun , Jin Yajun , Zhou Lixin , Yang Pingle , Qian Ying , Huang Xiaoyan , Min Mengmeng 
Published: January 2023

IntroductionIn 2020, the COVID-19 epidemic swept the world, and many national health systems faced serious challenges. To improve future public health responses, it's necessary to evaluate the performance of each country's health system.MethodsWe developed a resilience evaluation system for national health systems based on their responses to COVID-19 using four resilience dimensions: government governance and prevention, health financing, health service provision, and health workers. We determined the weight of each index by combining the three-scale and entropy-weight methods. Then, based on data from 2020, we used the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) method to rank the health system resilience of 60 countries, and then used hierarchical clustering to classify countries into groups based on their resilience level. Finally, we analyzed the causes of differences among countries in their resilience based on the four resilience dimensions.ResultsSwitzerland, Japan, Germany, Australia, South Korea, Canada, New Zealand, Finland, the United States, and the United Kingdom had the highest health system resilience in 2020. Eritrea, Nigeria, Libya, Tanzania, Burundi, Mozambique, Republic of the Niger, Benin, Côte d'Ivoire, and Guinea had the lowest resilience.DiscussionGovernment governance and prevention of COVID-19 will greatly affect a country's success in fighting future epidemics, which will depend on a government's emergency preparedness, stringency (a measure of the number and rigor of the measures taken), and testing capability. Given the lack of vaccines or specific drug treatments during the early stages of the 2020 epidemic, social distancing and wearing masks were the main defenses against COVID-19. Cuts in health financing had direct and difficult to reverse effects on health systems. In terms of health service provision, the number of hospitals and intensive care unit beds played a key role in COVID-19 clinical care. Resilient health systems were able to cope more effectively with the impact of COVID-19, provide stronger protection for citizens, and mitigate the impacts of COVID-19. Our evaluation based on data from 60 countries around the world showed that increasing health system resilience will improve responses to future public health emergencies.
Cardiovascular benefits of air purifier in patients with stable coronary artery disease: A randomized single-blind crossover study
Authors: Liu Zhe , Wang Qin , Li Na , Xu Chunyu , Li Yunpu , Zhou Jun , Liu Liu , Zhang Haijing , Mo Yang , Han Feng , Xu Dongqun 
Published: January 2023

BackgroundExposure to PM2.5 will accelerate the progression of cardiovascular diseases. Air purifier can reduce the PM2.5 exposure and theoretically alleviate the influence of PM2.5 on patients with stable coronary artery disease (SCAD). However, few studies of the protective effect showed significant results because the interferent effects of routine medication had not been taken into account. In order to explore the actual effect on patients with SCAD, we conducted a randomized single-blind crossover air purifier intervention trial.MethodLevels of PM2.5 exposure during intervention and cardiovascular indicators (inflammation, coagulation, plaque stability, and blood lipids) after intervention were detected, meanwhile the information of drug use was obtained by questionnaire. The kinds of drug used by more than 20% of the subjects were sorted out. And the influence of these drugs on cardiovascular indicators was summarized through literature review. Based on that, the drug use was included as a variable in linear mixed effects models that used to analyze the associations between PM2.5 exposure reduction by air purifier and cardiovascular indicators.ResultsThe result revealed that the interpretation contribution rate of drug use was more than that of PM2.5 exposure. The level of C-reactive protein significantly decreased by 20.93% (95%CI: 6.56%, 33.10%), 23.44% (95%CI: 2.77%, 39.39%) and 24.11% (95%CI: 4.21%, 39.69%) on lag1, lag01 and lag02 respectively, while the level of high-density lipoprotein cholesterol significantly increased by 5.10% (95%CI: 0.69%, 9.05%), 3.71% (95%CI: 0.92%, 6.60%) and 6.48% (95%CI: 2.58%, 10.24%) respectively on lag0, lag1 and lag01 associated with an interquartile range decrease of 22.51 μg/m3 in PM2.5 exposure.ConclusionThe study shows positive effects of air purifier on SCAD, and also provides methodological reference for future related research.
Association between exposure to greenness and atopic march in children and adults—A systematic review and meta-analysis
Authors: Wang Xue , Zhou Nan , Zhi Yuxiang 
Published: January 2023

IntroductionAllergic diseases are a global public health problem. Food allergy, atopic dermatitis (AD), allergic rhinoconjunctivitis, allergic rhinitis (AR) and asthma represent the natural course of allergic diseases, also known as the “atopic march”. In recent years, a large number of studies have been published on the association between greenness exposure and allergic diseases. However, systematic reviews on the association between greenness exposure and multiple allergic diseases or atopic march are lacking.MethodsIn this study, PubMed, EMBASE, ISI Web of Science, and Scopus were systematically searched. Meta-analyses were performed if at least three studies reported risk estimates for the same outcome and exposure measures.ResultsOf 2355 records, 48 studies were included for qualitative review. Five birth cohort studies, five cross-sectional studies, and one case-control study were included for asthma meta-analysis, respectively. Four birth cohort studies were included for AR meta-analysis. Our results support that exposure to a greener environment at birth reduces the risk of asthma and AR in childhood. In addition, higher greenness exposure was associated with decreased odds of current asthma in children.DiscussionThere was a large heterogeneity among the included studies and most of them did not specify the vegetation type and causative allergens. Therefore the study results need to be further validated. In addition, a small number of studies evaluated the association between greenness and food allergy, AD and allergic rhinoconjunctivitis. More research is needed to strengthen our understanding of the association between greenness and allergic diseases.
Artificial intelligence (AI) acceptance in primary care during the coronavirus pandemic: What is the role of patients' gender, age and health awareness? A two-phase pilot study
Authors: Chalutz Ben-Gal Hila 
Published: January 2023

BackgroundArtificial intelligence (AI) is steadily entering and transforming the health care and Primary Care (PC) domains. AI-based applications assist physicians in disease detection, medical advice, triage, clinical decision-making, diagnostics and digital public health. Recent literature has explored physicians' perspectives on the potential impact of digital public health on key tasks in PC. However, limited attention has been given to patients' perspectives of AI acceptance in PC, specifically during the coronavirus pandemic. Addressing this research gap, we administered a pilot study to investigate criteria for patients' readiness to use AI-based PC applications by analyzing key factors affecting the adoption of digital public health technology.MethodsThe pilot study utilized a two-phase mixed methods approach. First, we conducted a qualitative study with 18 semi-structured interviews. Second, based on the Technology Readiness and Acceptance Model (TRAM), we conducted an online survey (n= 447).ResultsThe results indicate that respondents who scored high on innovativeness had a higher level of readiness to use AI-based technology in PC during the coronavirus pandemic. Surprisingly, patients' health awareness and sociodemographic factors, such as age, gender and education, were not significant predictors of AI-based technology acceptance in PC.ConclusionsThis paper makes two major contributions. First, we highlight key social and behavioral determinants of acceptance of AI-enabled health care and PC applications. Second, we propose that to increase the usability of digital public health tools and accelerate patients' AI adoption, in complex digital public health care ecosystems, we call for implementing adaptive, population-specific promotions of AI technologies and applications.
COVID-19, mobility restriction, and sexual behavior among a cohort of people of reproductive age: Nigeria
Authors: Adekola Paul O. , Ugwu Favour C. , Amoo Emmanuel O. , Olawole-Isaac Adebanke , Cirella Giuseppe T. 
Published: January 2023

BackgroundOne of the non-pharmaceutical strategies adopted by various governments to control the spread of COVID-19 is mobility restriction (MR), popularly known as a lockdown. Evidence shows that MR has some unintended consequences, such as increased cases of domestic violence, rape, pornography, sex chats, incest, and other unhealthy sexual behaviors (SBs).MethodsThe study examined the influence of MR on SB in Owerri via a cross-sectional quantitative approach. A total of 425 interviewees were randomly chosen among people of a reproductive age. Data were analyzed using univariate, bivariate, and multivariate levels of analysis.ResultsA significant relationship exists between selected socio-demographic characteristics, such as age and marital status, and the ability of people to cope with sexual abstinence. Results from the logistic regression analysis further illustrated this observation as during MR people were twice as likely to engage in prolific sex chats that could spur other harmful SBs.ConclusionIt is recommended that people should be allowed to determine whether they would like to stay with their partners in subsequent lockdowns, or otherwise, to prevent some of the unpleasant SBs recorded.
3D-printed Model and guide plate for accurate resection of advanced cutaneous squamous cell carcinomas
Authors: Jiang Weiqian , Chen Peng , Cui Lei , Li Li , Shao Yan , Zhang Dekang , Xu Lin , Tao Ran , Chen Youbai , Han Yan 
Published: January 2023

GRAPHICAL ABSTRACTSchematic figure of the relationship between guide plate and tumor. The orange area represents the body surface; the red area represents the maximum range of tumor subcutaneous invasion in MRI; the yellow area represents the visible part of the tumor on the body surface; the blue area represents the projection range of the tumor on body surface and the green dotted line represents the guide plate range to help resection, which is 5 mm beyond the projection boundary.
Development and Validation of the COVID-19 Worries and Fears Scale
Authors: Cuadrado Esther , Arenas Alicia , Moyano Manuel , La Gamma Martina 
Published: January 2023

Objectives: How individuals perceive the risk of COVID-19 influences their mental health and protective behaviors. Therefore, the development of an instrument to capture COVID-19-related worries and fears is relevant. This study aims to develop and validate the CoV-WoFe to measure COVID-19-related worries and fears.Methods: An online questionnaire was completed by 593 participants during Christmas 2020 and by 328 participants during Summer 2021, from which 88 participants formed a longitudinal sample.Results: Analyses confirmed a robust adjustment for consistency over time and a gender-invariant bifactorial structure. Factor 1 represented worry about the health consequences of COVID-19 and Factor 2 represented the perceived physiological symptoms associated with fear of COVID-19. Construct validity was evidenced by: the expected relations between the CoV-WoFe and other theoretically related constructs; the serial mediating role of both dimensions in the relationship that security values establish with protective behaviors against COVID-19 and with anxiety; and the expected gender differences in the Cov-WoFe.Conclusion: The CoV-WoFe represents a short, valid, reliable, gender-invariant tool that is easy to apply in both the health professional and research context to assessCOVID-19-related worries and fears, which are variables of relevance for spread of the virus and for mental health.
Solid Fuel Use and the Progression of Multimorbidity in Middle-Aged Chinese Participants: A Prospective Cohort Study
Authors: Wu Tingting , Zhang Yue , Zhou Yaguan , Zhang Zifan , Cheng Yangyang , Liu Xiangtong , Xu Xiaolin 
Published: January 2023

Objectives: This study aimed to examine the association of solid fuel use for cooking and heating with the progression of multimorbidity.Methods: A total of 5,437 participants from the China Health and Retirement Longitudinal Study were included. Multivariate logistic regression models were used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for the associations of the independent and joint effects of solid fuel use for cooking and heating with the progression of multimorbidity.Results: The proportion of participants reporting solid fuel use for both cooking and heating was 59.0% at baseline. Solid fuel use for both cooking and heating was associated with the progression of multimorbidity (adjusted OR: 1.42, 95% CI: 1.19–1.70), compared with clean fuel use for both.Conclusion: Solid fuel use for cooking and heating play an important role in the progression of multimorbidity. Therefore, solid fuel reduction should be considered in developing multimorbidity control and prevention programmes.
Angiomyolipoma of the kidney—Clinicopathological analysis of 52 cases
Authors: Fejes Zsuzsanna , Sánta Fanni , Jenei Alex , Király István Előd , Varga Linda , Kuthi Levente 
Published: January 2023

The renal angiomyolipoma (AML) is a benign tumor characteristically composed of fat, smooth muscle tissue, and vessels. We collected AMLs from our nephrectomy database, reclassified them according to their histological appearance, recorded the demographic, clinical, and pathological parameters, and compared them with oncocytoma (RO) and renal cell carcinoma (RCC). Immunohistochemistry was ordered in 41 cases. In 2224 nephrectomies, we found 52 AMLs with a 53 mm median size. The mean age was 52.76. Forty-eight tumors were sporadic, while four were hereditary. The revision resulted in 31 classic, 13 leiomyoma-like, five lipoma-like, two epithelioid, and one AML with epithelial cysts. SMA was diffusely positive, except for the epithelioid type, while MelanA harbored stronger expression than HMB45. AML was more frequent in females and appeared ten and 7 years earlier than RO and RCC, respectively. The follow-up time was 7.42 years, and neither tumor-related death nor relapse occurred. AML is rare in nephrectomies and develops primarily in females in their 50s with an average size of 50–60 mm at the surgery. The histological appearance in order of frequency is classic, leiomyoma-like, lipoma-like, epithelioid, and cystic. The MelanA, HMB45, and SMA immunohistochemistry can support the light-microscopic findings.
Co-Infection of Potential Tick-Borne Pathogens of the Order Rickettsiales and Borrelia burgdorferi s. l. and Their Link to Season and Area in Germany
Authors: Hoffmann Angeline , Müller Thomas , Fingerle Volker , Silaghi Cornelia , Noll Matthias 
Published: January 2023

The prevalence of potential human pathogenic members of the order Rickettsiales differs between Borrelia burgdorferi sensu lato-positive and -negative tick microbiomes. Here, co-infection of members of the order Rickettsiales, such as Rickettsia spp., Anaplasma phagocytophilum, Wolbachia pipientis, and Neoehrlichia mikurensis as well as B. burgdorferi s.l. in the tick microbiome was addressed. This study used conventional PCRs to investigate the diversity and prevalence of the before-mentioned bacteria in 760 nucleic acid extracts of I. ricinus ticks detached from humans, which were previously tested for B. burgdorferi s.l.. A gltA gene-based amplicon sequencing approach was performed to identify Rickettsia species. The prevalence of Rickettsia spp. (16.7%, n = 127) and W. pipientis (15.9%, n = 121) were similar, while A. phagocytophilum was found in 2.8% (n = 21) and N. mikurensis in 0.1% (n = 1) of all ticks. Co-infection of B. burgdorferi s. l. with Rickettsia spp. was most frequent. The gltA gene sequencing indicated that Rickettsia helvetica was the dominant Rickettsia species in tick microbiomes. Moreover, R, monacensis and R. raoultii were correlated with autumn and area south, respectively, and a negative B. burgdorferi s. l. finding. Almost every fifth tick carried DNA of at least two of the human pathogenic bacteria studied here.