bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENERGY METABOLISM RELATED CANDIDATE GENE ASSOCIATION STUDY OF PERCEIVED PHYSICAL FATIGABILITY
Authors: Gay Emma , Santanasto Adam , Cvejkus Ryan , Wojczynski Mary , Feitosa Mary , Glynn Nancy W 
Published: December 2022

Abstract
Mitochondrial energy production decreases while fatigability increases with age. Genes associated with energy metabolism may contribute to fatigability. Using Long Life Family Study (LLFS), we initially assessed variants (SNPs) in 272 candidate autosomal genes involved in energy metabolism (previously associated with mitochondrial dysfunction disease) with perceived physical fatigability. Two generations of LLFS enrollees (N=2342, mean age=73.7, range 60-108 years) completed the Pittsburgh Fatigability Scale (PFS, 0-50, higher=greater fatigability) at Visit 2 (2014-2017). Physical fatigability prevalence was 42.1% (PFS≥15). Generalized linear mixed models assessed the association of each SNP with continuous PFS (GENESIS R package) adjusted for age, sex, field center, and family relatedness. We found no associations with perceived physical fatigability, all p&gt;2.5E-7 (Bonferroni multiple comparison corrected p-value). Next steps will examine variants in the mitochondrial genome and BTBD3, another promising candidate gene recently discovered. Genetic biomarker(s) may identify individuals susceptible to greater fatigability to target for early intervention.
PREVIOUS FALLS AND FEAR OF FALLING ON FUNCTIONAL LIMITATIONS: A LONGITUDINAL STUDY
Authors: Liu Kehan , Peng Wenting , Miyawaki Christina , Li Chunxiao , Zheng Yu , Tang Siyuan , Liu Minhui 
Published: December 2022

Abstract
Previous falls and fear of falling (FoF) are risk factors that affect older adults’ daily activities. However, it remains unclear about their combined effects on functional limitations. Using Round 1 (R1) and Round 2 (R2) data from the National Health and Aging Trends Study, we examined whether falls and FoF in R1 independently and jointly predict functional limitations in R2 and the moderating role of demographic factors in this relationship among community-dwelling older adults aged 65 years and older. Previous falls and FoF were ascertained by asking participants whether they had fallen down in the last year and worried about falling in the last month. Functional limitations included any difficulties with mobility, self-care, or household activities. Poisson regression models were used to analyze data. Of 5,956 participants, 16.4% had falls only, 14.3% had FoF only, 14.5% had both, and 54.8% had neither. In the full adjusted model, those who experienced concurrent falls and FoF had a higher risk of functional limitations than those without falls and FoF (Mobility: Incidence risk ratio, IRR=1.44, 95% CI: 1.33-1.57; Self-care: IRR=1.29, 95% CI: 1.20-1.38; Household tasks: IRR=1.32, 95% CI: 1.21-1.44), as well as those with falls only (Mobility: IRR=1.32, 95% CI: 1.21-1.44; Self-care: IRR=1.26, 95% CI: 1.17-1.35; Household tasks: IRR=1.18, 95% CI: 1.08-1.29) and FoF only (Mobility: IRR=1.38, 95% CI: 1.27-1.51; Self-care: IRR=1.26, 95% CI: 1.17-1.35; Household tasks: IRR=1.31, 95% CI: 1.20-1.43). The findings suggest that strategies to improve falls and FoF together could potentially help prevent functional limitations.
ENGAGING AND INVOLVING PEOPLE LIVING WITH DEMENTIA IN RESEARCH: WHAT TO (NOT) EXPECT
Authors: Roes Martina 
Published: December 2022

Abstract
Collaborating across disciplines, professions, and countries as well as engaging a variety of stakeholders has been a goal for researchers for a long time. Interestingly, when people living with dementia and their significant others are actively involved and become a co-researcher or a member of a patient advisory board, the perspective of what collaboration and/or engagement and involvement means, becomes blurry. The intersection between the individual reality of people living with dementia and researchers can be understood as (a) a door that opens up and leads to new (multiple) perspectives and understandings or (b) a disaster because misconceptions of dementia hinder mutual trust building. This presentation will provide examples on how to build trust and how sustain a relationship over the course of time (and progression of the disease). Since living with dementia is highly stigmatized this presentation will also reflect on the impact of misconceptions of dementia on engagement.
DOES PERSONALITY ALWAYS MATTER? EXAMINING THE MODERATING EFFECT OF AGE ON THE PERSONALITY-HEALTH LINK
Authors: Luo Jing , Zhang Bo , Graham Eileen , Mroczek Daniel 
Published: December 2022

Abstract
The current research examined how the associations between the level and changes in the Big Five personality traits and different types of health outcomes (self-rated, physical, cognitive, and physiological health outcomes) differ across ages over the lifespan (Sample 1, age range: 15-100) and during the aging process (Sample 2, age range: 50-109) in particular. Using data from the two large longitudinal studies, we observed three important patterns based on the results. First, levels and changes in personality traits demonstrated substantial effects on health across different life phases, with the effects observed even in very old ages. Second, overall, the prospective relations between personality traits/changes in personality traits and health outcomes increased in strength in mid adulthood and/or early stages of late adulthood; however, the strength of their connections diminished in very old ages. Finally, there were some trait-specific and health outcome-specific patterns in the age-differential associations between personality and health.
THE VALUE OF BALANCE CONFIDENCE IN OLDER ADULT FALL RISK ASSESSMENT
Authors: Hughes Tiffany , Ickert Edmund , Kellar Garrett , Kerns Lucy , Berg-Carramusa Cara 
Published: December 2022

Abstract
Fall risk assessment traditionally focuses on objective physical performance. Balance confidence, a subjective measure of physical function, may provide important information to better predict fall risk and guide assessment and intervention strategies. This study examines the associations of balance confidence congruency with physical performance measures and fall occurrence. One-hundred-fifty-five community-dwelling adults aged 60 and over completed a comprehensive fall risk assessment including physical performance tests (timed up and go, 4-stage balance, 30-second chair stand, and 4-M gait speed), activities-specific balance confidence (ABC) scale, and self-reported falls in the past year. Four groups were created based on congruency between balance confidence (low vs. high) and each physical performance measure or overall fall risk category (at fall risk vs. not at fall risk, based on the STEADI tool kit). Poison regression analyses, adjusted for age and gender, tested the association between group membership and number of falls in the past year. Participants with high balance confidence and at fall risk based on 4-stage balance performance (Estimate=0.88, p &lt; 0.001), or high balance confidence and at fall risk following the STEADI screening algorithm (Estimate=0.69, p = 0.003) were at increased risk of more falls compared to participants in the group with high balance confidence and not at fall risk. These results suggest that older adults who overestimate their balance relative to their physical performance may be at increased fall risk, and that participant subjective reporting of physical performance should be paired with objective physical performance measures to better identify older adults at fall risk.
IS ONLINE ACCESS AND ACTIVITY ASSOCIATED WITH BETTER MOOD IN OLDER ADULTS LIVING ALONE DURING THE COVID-19 PANDEMIC?
Authors: Koren Yael , Leveille Suzanne 
Published: December 2022

Abstract
Older adults living alone during the COVID-19 pandemic face risks for social isolation and mental health problems. The goal of this study was to investigate the relationship between access to internet-capable devices or utilizing email/ texting, social networking [SN], or health-related internet use [HIU] and psychological outcomes (depressive and anxiety symptoms) among older adults living in the community during the early months of the pandemic, March, 2020-May, 2020. A cross-sectional analysis of the National Health and Aging Trends Study (NHATS, Round 10) was conducted, using multivariable logistic regression. Adults aged ≥85y were more likely to live alone than those aged 65-84y (34.3% and 24.9% respectively, p&lt; 0.001). Additionally, 39.6% of women lived alone compared with 21.2% of men (p&lt; 0.001). Fewer people living alone had access to an internet-enabled device than those living with others (10.4% and 5.4%, respectively). Among older adults living alone, utilizing SN and HIU was associated with lower likelihood of depression or anxiety (Depression: adj.OR 0.36, CI 0.17-0.77; Anxiety: adj.OR 0.31 CI 0.13-0.76). Alternatively, among those living with others, using email/ texting was associated with lower likelihood of depression and anxiety (Depression: adj.OR 0.23, CI 0.13-0.46, Anxiety: 0.33 CI, 0.17-0.67). In summary, internet activity was associated with reduced risk for depression and anxiety among older adults who lived alone or with others early in the pandemic. Further research is needed to better understand the potentially mitigating role of internet activities among older adults at risk for isolation and associated mood disturbances.
PATIENT PORTAL USE WITHIN OLDER ADULTS' FAMILY CAREGIVING NETWORKS
Authors: Burgdorf Julia , Fabius Chanee , Wolff Jennifer 
Published: December 2022

Abstract
The patient portal (hereafter, “portal”) is an online platform allowing patients to view health information, perform health management tasks, and directly message clinicians. Millions of older adults co-manage their health care with family caregivers, yet little is known about the extent to which caregivers use the portal alongside or on behalf of patients. We examined linked data from the 2017 National Health and Aging Trends Study (NHATS), National Study of Caregiving (NSOC), and American Community Survey for 1,675 (weighted n=8,511,568) older adults with disability. We measure older adult and caregivers’ respective use of the older adult’s portal from NHATS and NSOC. We use weighted, multivariable, ordered logistic regression to model transition from older adult using the portal alone, to co-using the portal with caregivers, to a caregiver using the portal on the older adult’s behalf. We find that 9% of older adults use the portal on their own, 2% co-use the portal with a caregiver, and 15% have a caregiver who uses the portal on their behalf (74% have no portal use). In adjusted models, older adults had higher odds of a caregiver using the portal on their behalf (compared to the older adult using the portal alone or in tandem with a caregiver) if they were older (aOR: 1.12; p&lt; 0.001), female (aOR: 2.08; p&lt; 0.01), had probable dementia (aOR: 7.04; p&lt; 0.001), were homebound (aOR: 3.78; p&lt; 0.01), attended doctors’ visits with a caregiver (aOR: 3.10; p&lt; 0.01), or lived in a census tract with low broadband accessibility (aOR: 5.76; p&lt; 0.01).
ANOCRITICISM AND THE PERFORMANCE OF MASCULINITY IN OLDER MEN
Authors: de Medeiros Kate 
Published: December 2022

Abstract
While anocriticism is a feminist framework often applied in the context of literary gerontology, this paper uses an anocriticism approach to consider how hegemonic masculinities and old age reveal a separation between cultural stereotypes of age and chronological age. Narratives from 5 men aged 65 and over, who participated in a qualitative study on everyday attributions of depression, were analyzed using an anocriticism framework. Results revealed that participants both claimed and contested their chronological age as an identity marker. Of particular note were claims related to the stereotype of loss of vigor in later life, with each man making a clear point to affirm his virility and sexual prowess independent of other interview questions. Overall, findings point to an important way to read interview data through an anocritical lens, paying particular attention to ways that power are questions and performed in relation to age.
FRAILTY AND SOCIOECONOMIC STATUS IN BRAZIL, CHINA, AND INDIA
Authors: Seligman Benjamin , Agarwal Arunika , Bloom David 
Published: December 2022

Abstract
Frailty, the vulnerability to poor health outcomes following physiologic stress, acts as a measure of physiological age that can be used to compare the health of older populations. Using a frailty index validated in multiple countries, we looked at the relationship between four measures of socio-economic status (SES) and frailty in Brazil, China, and India. For SES measures, we considered within-country income and wealth deciles, education level, and rural residence. Analysis used beta regression, first within each country, then with combined data with country fixed effects and country-by-SES interactions. We found evidence of strong, statistically significant negative associations between education level and frailty in all three countries. Associations between frailty and income or wealth decile or rural residence were small and inconsistently statistically significant. This demonstrates the key role of education for healthy aging and the value of harmonized frailty measures for comparative studies of older populations.
AS YOU SOW, SO SHALL YOU REAP: ADULTS' MEMORIES' EFFECT OF PARENTAL ACCEPTANCE REJECTION IN CHILDHOOD ON AGING PARENTS
Authors: Ali Sumbleen , Rohner Ronald 
Published: December 2022

Abstract
Little is known how adults’ memories of parental acceptance-rejection in childhood influence their behavior toward their aging parents. Grounded in interpersonal acceptance-rejection theory (IPARTheory), this study attempts to better understand how early parent-child relationships affect adult offspring who provide care to their parents in later life. Data were collected from 41 adult offspring. Findings revealed that adults who felt rejected by their parents in childhood reported fewer positive caregiving behaviors toward their now aging parents, were less satisfied with social activities with their parents, spent less time with them or visited them less frequently, and revealed less overall concern for their aging parents. Results were consistent with IPARTheory’s expectations that if parents reject their children, then parents place their own dependent old age at the risk of counter rejection: As you sow, so shall you reap. Such findings may help researchers, clinicians, and practitioners better understand the well-being of aging adults.
BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS OF DEMENTIA (BPSD) IN HOSPITALIZED OLDER ADULTS WITH AD/ADRD
Authors: Marziliano Allison , Makhnevich Alex , Burns Edith , Diefenbach Michael , Sinvani Liron 
Published: December 2022

Abstract
The epidemiology of Behavioral and Psychological Symptoms of Dementia (BPSD) in hospitalized older adults with Alzheimer’s Disease (AD) and AD-related dementias (ADRD) has not been well-characterized. The purpose of this abstract is to examine the prevalence, patient-level factors and hospital outcomes associated with BPSD in hospitalized older adults with AD/ADRD. Data was extracted from the electronic health record (EHR) of older adults (aged 65+ years) with AD/ADRD, admitted to one of 7 hospitals in the greater New York metropolitan area during 2019. Three independent coders reviewed the EHR and recorded the presence or absence of the 11 domains of the Neuropsychiatric Inventory (NPI), a validated measure of BPSD. Of N = 1,865 hospitalized older adults with AD/ADRD, 1,564 had BPSD (prevalence = 83.9%). The most commonly reported BPSD were agitation (72.3%) and anxiety (17.7%). Older age (M = 84.6, SD = 7.6 versus M = 82.4, SD = 7.8, p = .000) and antipsychotic medication use prior to hospital admission (91% of the older adults who used home antipsychotics had BPSD, p = 000) was associated with BPSD. With regard to hospital outcomes, BPSD was associated with: increased mortality (of those who died, 90.6% had BPSD, p = .006), and increased likelihood of readmission to the hospital within 30 days of discharge (of those readmitted, 89.3% had BPSD, p = .007). Given its high prevalence and associated poor outcomes, recognizing and managing BPSD in hospitalized patients with AD/ADRD is critical to improving quality of care for this vulnerable population.
COMMUNITY ENGAGEMENT: INDIGENOUS AND NONINDIGENOUS RESEARCHERS
Authors: Lewis Jordan , Kim Steffi 
Published: December 2022

Abstract
In response to populations that have been chronically underserved and underrepresented within the social sciences, scholars have outlined the need for community-based engagement strategies and research methodologies that are able to represent the voices of those communities to promote culturally informed, appropriate, and driven health initiatives. This symposium introduces and discusses Indigenous research methodologies that are empowering and emphasize the knowledge and wisdom of Indigenous Elders, shares urban Elder engagement strategies, explores engagement strategies for Indigenous and non-Indigenous researchers, and describes the impacts of exclusion of Indigenous voices from research. The first presentation by Maria Crouch and her colleagues will introduce an Elder-centered research methodology as exemplified by two research studies. The second presentation by Steffi Kim focuses on outreach and research engagement strategies to reach Alaska Native Elders in the urban environment. The third presenter, Jordan Lewis, shares and discusses community-based research as an insider and outsider in your own community, outlining research practices, positionality, and accuracy in research. Finally, Lyn Holley will discuss themes emerging from her review of the literature that explored the impacts of the application of “top-down” Eurocentric approaches to inquiry on American Native people and the implications of these findings.
ELDER-CENTERED RESEARCH METHODOLOGY: RESEARCH THAT DECOLONIZES AND INDIGENIZES
Authors: Crouch Maria , Kim Steffi , Asquith-Heinz Zayla , Decker Elyse , Andrew Nyche , Rosich Rosellen , Lewis Jordan 
Published: December 2022

Abstract
Alaska Native (AN) Elders have historically been underrepresented in research. Innovative AN research posits that practice-based evidence is fundamental to culturally grounded, multifaceted methods. Semi-structured interviews were conducted with 34 AN Elders and 12 AN and non-Native caregivers in two studies exploring cultural understandings of memory and successful aging. The design and implementation of these studies employed Elders at every level of the research, ensuring cultural relevancy, outcomes, and dissemination activities. Findings reflect the benefits of engaging AN Elders in research and reveal methods for best practices: 1) creating Advisory councils; 2) identifying stakeholders 3) weaving together Elder and Western knowledge systems; and 4) the reciprocal nature of Elder engagement and wellbeing. This complimentary research builds on Elder-centric principles and lays the foundation for an Elder-centered research methodology that can be adapted and applied in other studies to encourage engagement of older adults in meaningful, restorative, and enculturated ways.
SUPPORTING NURSING HOME MANAGERS TO ACT ON PERFORMANCE FEEDBACK DATA: A PROVINCEWIDE IMPLEMENTATION
Authors: Estabrooks Carole , Saeidzadeh Seyedehtanaz , Bryan Stirling , Norton Peter , Ginsburg Liane , Hoben Matthias , McLeod Don 
Published: December 2022

Abstract
INFORM (Improving Nursing home care through Feedback on perfoRMance data) is a tested research intervention targeting care managers that demonstrated positive two year follow up results and has subsequently been shaped into an operationally acceptable “implementation package”. This package or innovation is being scaled up in one Canadian province’s total Long-Term-Care (LTC) home population with in depth process evaluation during the first cohort of LTC homes. This evaluation will, among other things, assess sector needs for adaptation (vs fidelity). At its core INFORM is designed to address managers’ learning needs with respect to using data to make positive change in a continuous learning loop. We will discuss the transformation of a research intervention to a sector innovation and report on interim process evaluation results.
THE ROLE OF COPING IN THE ASSOCIATION BETWEEN DISCRIMINATION AND HEALTH OVER TIME IN SEXUAL MINORITY OLDER ADULTS
Authors: Nelson Christi 
Published: December 2022

Abstract
While research on lesbian, gay, and bisexual (i.e., sexual minority) middle-aged and older adults has increased over the past decade, there is still a critical need for more research on the health and resilience in this marginalized group, especially longitudinal research. This study examined the differences in the associations between perceived daily discrimination and the physical and mental health of sexual minority and heterosexual adults over time and assessed the moderating effects of problem-focused and emotion-focused coping on these associations. The sample for this study consisted of sexual minority (n=162) and propensity matched heterosexual (n=324) middle-aged and older adults (mean age at baseline=43 years, SD=12.5) with data from three waves of the Midlife in the United States (MIDUS) study, spanning approximately 20 years. Results found that, for sexual minority participants, reporting higher perceived discrimination was associated with a greater number of chronic conditions at baseline, but was also associated with a significant decrease in the number of chronic conditions over time. For the heterosexual participants, both high and low perceived daily discrimination was associated with an increase in the number of chronic conditions over time. The results of this study also found significant moderating effects of coping on the number of chronic conditions and self-rated mental health over time. Problem-focused coping may protect against the negative effects of discrimination on health. These results are suggestive of a “steeling” effect or a resistance to stress achieved through exposures to adversity for the sexual minority middle-aged and older adults in this study.
OVERCOMING RECRUITMENT APPROACHES TO IDENTIFY PARTICIPANTS WITH DEMENTIA
Authors: Galik Elizabeth 
Published: December 2022

Abstract
Clinically the work up for dementia often includes a history and physical, neuropsychiatric screening measures and neuroimaging. These assessments are neither practical nor realistic when identifying participants for research studies. To confirm a diagnosis of dementia for study participants in the FFC-AC-EIT study we developed a measurement model. The model included four measures: the AD8, the Functional Activities Questionnaire, the Clinical Dementia Rating Scale, and the Saint Louis University Mental Status Examination. In the first 346 patients consented, 176 were enrolled and 158 were ineligible. The mean age of the participants was 80.70 (SD=9.60) and the majority were female (64%) and white (66%). There was evidence of reliability based on internal consistency and construct validity based on model fit using Rasch analysis and Structural Equation Modeling. All four measures are recommended as a pragmatic way in which to comprehensively determine evidence of dementia for research studies.