bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of water-soluble fertilizers on the yield and biochemical composition of table watermelon of medium and late ripening
Authors: Galichkina E. A. , Nadezhkin S. M. 
Published: February 2023

Relevance. The nutritional value of gourds is quite high and is of great importance in the life of the human body. A significant point in modern melon growing is to increase yields without reducing the quality of the products obtained. Therefore, it is necessary to develop new methods of cultivation technologies that allow obtaining stable fruit yields without reducing the quality of table watermelon products of different ripeness groups, in the climatic conditions of the Volgograd region.Material and methodology. The object of research is a watermelon of medium ripening, variety Zemlyanin, and late ripening, variety Kholodok. We studied new types of water-soluble fertilizers Fe chelate, as well as Vegetable Aquarin, by using them for soaking seeds before sowing and processing plants during the growing season.Results. The use of chelated fertilizers in the technology of growing table watermelon of medium and late ripening is an effective technique for obtaining stable yields. The use of water-soluble fertilizers, with various methods of their use, provided an increase in the yield of Zemlyanin watermelon by 2.7-27.8%, and Kholodok watermelon by 2-22.4% in comparison with the control (without treatments). The largest fruits were obtained in the variant Aquarin vegetable (plant processing) Zemlyanin variety - 6.8 kg and Kholodok variety - 8.4 kg. A comparative analysis of the biochemical composition of fruits showed that water-soluble chelate fertilizers do not have a negative effect on the accumulation of nitrates in varieties of medium and late ripening. As a result of research, a positive effect of water-soluble micronutrient fertilizers has been revealed on improving the quality of fruits, which increased the content of ascorbic acid and sugars.
Efficiency of herbicides on cropped onion (<i>Allium cеpaL.</i>)
Authors: Bernaz N. I. , Irkov I. I. 
Published: February 2023

Relevance. Onions are a traditional vegetable crop that is in demand all year round. To obtain high and stable yields, it is necessary to renew the assortment of herbicides in the fight against weeds, to use compositions of preparations of different spectrum of action, toxic to the most harmful weeds and giving the maximum herbicidal effect with minimal labor and financial resources.Results. The article presents the results of tests of new herbicides Bandura and Boxer, unregistered in the Russian Federation on onions, at optimal rates, which showed high selectivity to the crop, but were inferior in efficiency to the Stomp Professional standard. The tank mixtures of Bandura and Stomp Professional with Dual Gold were more effective, exceeding the level of efficiency of the standard. Due to the action of the mixture Stomp Professional + Dual Gold (2 + 1 L / ha), the weediness of onion crops decreased by 78-89% (by quantity) and by 87 - 95% (by weight), which contributed to a significant increase in the yield of bulbs by 12.2% in comparison with control. The efficiency of Goal 2E 0.5 L/ha (42%) in the phase of 2 leaves of onion was insignificant due to the overgrowth of most annual dicotyledonous weeds by the time of treatment (3-10 leaves). The herbicide completely eliminated weeds at an early stage (up to 5 leaves), as well as older white and smoky grass. The remaining weeds experienced oppression in the form of suspension of growth, twisting and necrosis of leaves. Goal 2 E must be included in the system of protective measures against the background of pre-emergence herbicide treatment to suppress annual dicotyledonous weeds, poorly controlled by soil herbicides.
Agrochemical methods for increasing the yield of root chicory
Authors: Vyutnova O. M. , Smirnova I. V. , Novikova I. A. , Maksimova K. S. 
Published: February 2023

Relevance. The effectiveness of fertilizers depends on the need of plants for nutrients and on the ability of the soil to meet this need. According to the Research Institute of Raw Materials of the Alcohol Industry, the responsiveness of chicory to individual substances changes dramatically during the growing season. In the first period of its development, chicory responds sharply positively only to phosphorus. In the future, the phosphorus efficiency remains stable for two months and by the end of the growing season, attenuation begins. The potash efficiency, on the contrary, is low in the first months, and by the end of the growing season, in contrast to the action of phosphorus, it gives a sharp rise. The efficiency of nitrogen during the growing season occupies an average position between the efficiency of phosphorus and potassium.Methodology. The aim of the research was to identify the most effective doses of macro- and microelements and methods of their application (basic and top dressing) to ensure maximum yields of root chicory root crops. The experiments were carried out in the Nonchernozem zone of the Russian Federation in the Rostov district of the Yaroslavl region on the experimental field of the Rostov experimental station for chicory¬ – a branch of the FSBSI FSVC.Results. As a result of the conducted studies, it was found that an increase in the dose of nitrogen nutrition against the background of phosphorus-potassium fertilizer increased the yield of root chicory root crops, fractional application of mineral fertilizers is more effective compared to the main application, the introduction of boron and cobalt increased the content of inulin and sugars in root crops. The inulin content increased as the dose of nitrogen fertilizers increased.
First treatment with venovenous extracorporeal membrane oxygenation in Maribor
Authors: Skok Kristjan , Markota Andrej , Svenšek Franc , Sinkovič Andreja 
Published: February 2023

Purpose: We report on the first patient with refractory hypoxemia treated with venovenous extracorporeal membrane oxygenation (VV ECMO) at the Medical Intensive Care Unit of the University Medical Centre Maribor.
Case report: A 52-year-old male was admitted after successful cardiopulmonary resuscitation from out-of-hospital cardiac arrest (first rhythm was ventricular fibrillation, with 40 min to return of spontaneous circulation). The patient underwent primary percutaneous revascularization of the left anterior descendingcoronary artery with insertion of one coronary stent. Hypoxemia was present during patient transportation and the procedure and continued to worsen after admission. Due to refractory hypoxemia caused by aspiration pneumonia, treatment with the VV ECMO was initiated. The ECMO procedure wasperformed without complications and led to improvement in gas exchange and lung mechanics. The patient was then successfully weaned from ECMO, decannulated, and extubated. After extubation, the patient’s course of treatment was complicated by hospital pneumonia and catheter-related blood stream infection.As his state deteriorated, reintubation was necessary. Despite intensive treatment, the patient died on day 30.
Conclusions: Response to the VV ECMO treatment of refractory hypoxemia due to aspiration pneumonia was positive and without complications. In spite of initial improvement, the patient died after several weeks due to recurring infection and septic shock.
Thiel's embalming method: review of the literature and our institute's experience
Authors: Kocbek Lidija , Rakuša Mateja 
Published: February 2023

Purpose: We aimed to present one of the best researched methods of cadaver preservation, Thiel's method, and share our own 9–year experience in comparison with that of the literature.
Methods: Thiel's embalming method uses intravascular injection of a solution combined of several chemicals, such as water–based mixtures of monopropylene glycol, ammonium nitrate, potassium nitrate, sodium sulfite, boric acid, chlorocresol, formaldehyde, ethanol, and morpholine. Initial perfusion via the carotid and femoral arteries is followed by immersion in a cadaver storage basin in embalming solution for at least 4–6 months. After this, cadavers are stored in plastic bags in refrigerators and are used for months to years.
Results: Since 2008, we have successfully embalmed 16 cadavers using Thiel's method. Due to the beneficial characteristics of this method, Thiel's embalmed cadavers have become an important part of our education and research. Despite initial technical difficulties, we managed to upgrade the method and assure better long–lasting preservation.
Conclusions: Thiel embalmed cadavers resemble realistic living bodies and serve as an appropriate model for teaching and research.
Correlation of Coronary Heart Disease Patient Assessments of Chronic Illness Care and Quality of Care Procedures
Authors: Tušek-Bunc Ksenija , Petek-Šter Marija , Petek Davorina 
Published: February 2023

Purpose: Patient-centered assessment of chronic illness care is replacing the assessment of satisfaction, which does not cover all dimensions of care. Patient assessments reflect both the quality of chronic illness care and provide feedback to healthcare workers about their work. The study aim was to investigate the patient-centered assessment of coronary heart disease (CHD) patients and its correlation with the care that was delivered.
Methods: This cross-sectional study evaluated data obtained from the patient medical records and surveyed patients using the Patient Assessment of Chronic Illness Care (PACIC) questionnaire. A descriptive analysis of the overall and domain-specific responses to the PACIC questionnaire was conducted and the association of the results with delivery of care data in the patient records was determined by Pearson's correlation coefficient.
Results: The study sample included 768 of 1080 CHD patients (71,1%) at 36 family medicine practices who completed the PACIC questionnaire. The mean age of the respondents was 68.3 ± 10.7 years and the overall PACIC score was 3.3 ± 0.9. The highest PACIC scores were delivery system design (3.7), patient activation (3.7), and problem solving (3.6). Follow-up received the lowest score (2.8). Quality of delivered care and PACIC scores were correlated (r = 0.10, p = 0.009).
Conclusions: CHD patients highly rated all aspects of chronic care included in the PACIC questionnaire. They were least satisfied with the follow-up and coordination aspects of chronic care. The process indicators of care were positively correlate with patient assessment of care.
Analysis of pregnant women with the diagnosis of gestational diabetes mellitus without oral glucose tolerance test confirmation in early pregnancy
Authors: Zavratnik Andrej , Krajnc Mitja 
Published: February 2023

Purpose: The aim of this analysis was to determine the proportion of pregnant women referred by gynaecologists to the outpatient diabetes clinic of the University Medical Centre Maribor with a diagnosis of gestational diabetes mellitus (GDM) based on inappropriately measured fasting plasma glucose (FPG). Additionally, we wanted to compare pregnancy outcomes in subgroups diagnosed later as having GDM vs. no–GDM with oral glucose tolerance testing (OGTT) in the 24th to 28th week of pregnancy, but declared as “probably not having GDM” in early pregnancy.
Methods: We reviewed retrospectively data on 81 pregnancies referred to our centre, from August 2013 to July 2014, with a diagnosis of early GDM that we did not con-firm with OGTT retesting. After retesting, women were followed up routinely by a gynaecologist, but those with a diagnostic OGTT, performed in the 24th to 28th week, were referred back to a diabetologist.
Results: The age of the entire cohort was 30.5±4.7 years, and 91% were ≥25 years old; 40% were overweight before pregnancy. The period of fasting before FPG measurement was less than 8 hours in 36%. When comparing the GDM vs. no–GDM subgroups, a higher proportion of women with GDM were fasted for less than 8 hours before FPG measurement (75% vs. 32%; p=0.022), and birth weight was higher for women with GDM (3778±588 g vs. 3316±618 g; p=0.048). There were no differences in macrosomia, eclampsia, Caesarean delivery and birth trauma.
Conclusion: The accuracy of the diagnosis of early pregnancy GDM can be improved by following the FPG measurement protocol. When a single FPG in early pregnancy is near normal we suggest retesting with an OGTT. This approach probably has no adverse effect on pregnancy outcomes.
Microvessel density and PSA level in prostatic adenocarcinoma of Gleason score 6 and 7
Authors: Dariš Barbara , Munda Miha 
Published: February 2023

Purpose: The aim of this investigation was to determine the differences in microvessel density (MVD) and serum levels of prostate-specific antigen (PSA) between groups of patients with Gleason score (GS) 6 prostatic adenocarcinoma and patients with GS 7 prostatic adenocarcinoma.
Methods: The study included a series of 100 patients with prostatic adenocarcinoma. Tumor specimens were divided into two groups: GS 6 (52 cases) and GS 7 (48 cases). Intratumoral microvasculature was determined by immunohistochemistry using an antibody against endoglin. Endoglin stained microvessels were observed in and around the tumor, but weak or no staining of blood vessels was seen in non-neoplastic tissue. Areas of maximal angiogenesis within the tumor were identified and microvessels were counted at ×400 magnification (0.19 mm2 field).
Results: The GS 6 specimens did not significantly differ in MVD per field (24.5 vs. 29.0; P=0.46) or MVD per mm2 (109.3 vs. 129.6; P=0.78) when compared with the GS 7 specimens. No significant difference in mean serum levels of PSA between the two groups was observed (8.5 vs. 10.1 ng/mL; P=0.66). MVD per mm2 was not correlated with PSA (r=0.1; P=0.62). The age of patients at diagnosis was not significantly different between the two groups (63.0 vs. 65.0 years; P=0.84).
Conclusion: Our results show no significant differences in neovascularization and PSA level between Gleason score 6 and 7 prostatic adenocarcinoma.
Subendocardial viability ratio, ambulatory blood pressure monitoring and serum biomarkers for cardiovascular disease in chronic kidney patients
Authors: Piko Nejc , Šrot Tajda , Hojs Nina , Bevc Sebastjan , Hojs Radovan , Ekart Robert 
Published: February 2023

Purpose: Chronic kidney disease (CKD) is associated with a higher prevalence of cardiovascular diseases. The pulse wave analysis measures the aortic pressure waveform based on noninvasive peripheral pressure recording. The subendocardial viability ratio, as part of the pulse wave analysis, is a noninvasivemeasure of microvascular coronary perfusion.
Methods: In the present study, we investigated the relationship between the subendocardial viability ratio, 24-h ambulatory blood pressure measurements, and serum biomarkers to determine the risk for cardiovascular disease in patients with CKD. A pulse wave analysis using applanation tonometry was performed in 86 patients with CKD. Serum biomarkers were measured in patients, and the patients were grouped according to the median value of the subendocardial viability ratio.
Results: The mean age of the patients was 60 ± 13 years; 65% of the patients were men, and the mean subendocardial viability ratio was 151% ± 34%. Patients with CKD in the lower subendocardial viability ratio group (<151%) had significantly lower hemoglobin (p=0.002) and higher NT-proBNP (p=0.034), serum phosphorus (p=0.04), augmentation index (p=0.003), 24-h pulse (p=0.004), and 24-h pulse pressure(p=0.003).
Conclusion: Our findings suggest that patients with CKD with a subendocardial viability ratio below 151% have a higher cardiovascular risk.
Diagnostic relevance of free light chain indices and their relation to the clinical presentation of multiple sclerosis
Authors: Karakatič Sanja , Magdič Jožef , Karakatič Sašo , Omerzu Tomaž , Modrič Evgenija , Hojs Fabjan Tanja 
Published: February 2023

Purpose: Cerebrospinal fluid (CSF) free light chains (FLC) are of promising diagnostic importance in patients with multiple sclerosis (MS). However, research is required to confirm their utility as part of the diagnostic criteria for MS. In addition, very few publications can be found addressing the relationship of FLCs to the clinical presentation at the onset of MS. We aimed to evaluate the diagnostic performance of the FLC kappa and lambda indices, and explored their relationship to the number and type of functional systems (FS) involved.
Methods: FLC indices were determined in paired CSF and serum samples from 71 patients with noninflammatory neurological diseases (non-MS, n = 29) and new-onset MS (MS, n = 42). The latter were further divided into two groups with mono- and polysymptomatic presentation. FS involvement was evaluated in accordance with the Expanded Disability Status Scale (EDSS).
Results: Using both FLC indices along with the age and sex of patients, the diagnostic accuracy of MS was higher (AUC, 0.991; sensitivity, 95.5%; specificity, 95.8%) than that observed when using either the lambda index (AUC, 0.677; sensitivity, 68.0%; specificity, 60.0%) or kappa index (AUC, 0.957; sensitivity, 88.5%; specificity, 88.0%) alone. No differences were observed in the lambda (U = 78.0; p = 0.749) or kappa indices (U = 82.0; p = 0.885) between mono- and polysymptomatic patients. Nor was a correlation found between FLC indices and EDSS scores.
Conslusion: FLC indices could be useful diagnostic markers for MS. However, such indices do not differentiate between clinical presentations at disease onset and are not correlated with baseline EDSS scores.
Case report: Pelvic abscess after cesarean section and hysterectomy
Authors: Krajnc Klavdija , Takač Iztok , Mujezinović Faris , Horvat Matjaž , Kuder Lucija 
Published: February 2023

Purpose: The purpose of this article was to present the case of a pelvic abscess, which developed after an emergency cesarean section followed by a hysterectomy, to identify the risk factors, and describe a minimally invasive technique for abscess drainage.
Case report: We present a 30-year-old patient at 35 + 4 weeks gestation who had an emergency cesarean section. The indication for the cesarean section were four previous cesarean sections. She had severe postpartum bleeding due to uterine atony and disseminated intravascular coagulopathy, which did not resolve with conservative treatment. A few days later, a pelvic abscess formed and complicated the post-operative recovery.
Conclusion: A pelvic abscess is a rare complication following obstetrics surgery; however, it is important to take
Case report: Endodontic treatment of a permanent maxillary first molar with three roots and six root canals
Authors: Novak Marko , Štamfelj Iztok 
Published: February 2023

Purpose: This study aimed to report the diagnosis and management of a permanent maxillary first molar (PMFM) with unusually complex root canal morphology.
Case report: A 30-year-old male patient was referred to the endodontic department to continue endodontic treatment of the left PMFM. The referring dentist could not establish the patency of the canals in the mesiobuccal and distobuccal roots. Radiographically, the tooth had three almost straight roots associated with periapical radiolucencies, indicating periapical periodontitis. The examination of the pulp chamber floor, using a dental operating microscope, revealed the presence of six root canal orifices, three in the mesiobuccal root, two in the distobuccal root, and one in the palatal root. No confluence of multiple canals was detected using the electronic apex locator and K-files. The canals were shaped and cleaned with reciprocating nickel-titanium instruments and obturated using gutta-percha cones and a bioceramic sealer. After 2 years, the patient was asymptomatic and the tooth was clinically and radiographically without pathological findings.
Conclusions: Careful examination of the pulp chamber floor using magnification and illumination is important for successfully managing complex canal morphologies. During endodontic treatment, dentists must consider that the PMFM may have more than four root canals.
Predicting short-term (30-day) mortality in patients with ischemic stroke using the baseline score of the National Institutes of Health Stroke Scale
Authors: Hojs Fabjan Tanja 
Published: February 2023

Purpose: The National Institutes of Health Stroke Scale (NIHSS) was developed to measure neurologic outcome and recovery in patients with stroke. The aim of our study was to establish the validity of the NIHSS on short-term (30-day) mortality in patients with ischemic stroke.
Methods: All 402 patients (216 males) with acute ischemic stroke hospitalized over 1 year were included in the study. Information on the presence of diabetes mellitus and smoking habits was obtained by a questionnaire. Systolic and diastolic blood pressure was measured upon hospital admission. The body mass index was calculated. Laboratory data were assessed in the first 24h after stroke onset. The National Institutes of Health Stroke Scale (NIHSS) was employed upon hospital admission. Patients were then followed up for 30 days.
Results: The mean age of patients was 70.89 years (range, 36–96 years). Women were older than men (P<0.0001). There were 49 (12.2%) deaths in the first 30 days. Patients who died had a higher NIHSS score upon hospital admission (P=0.0001), were older (P=0.013), had higher high-sensitivity C-reactive protein (hsCRP) levels (P=0.0001) and lower albumin levels (P=0.016). With Cox multivariable regression analyses, NIHSS score (P=0.0001) as well as levels of total cholesterol (TC) (P=0.004) and low-density lipoproteincholesterol (LDL-C) (P=0.016) were predictors of 30-day mortality. After the addition of age as a variable, NIHSS score (P=0.0001) as well as levels of TC (P=0.006) and LDL-C (P=0.025) remained predictors of mortality.
Conclusion: The NIHSS is a good predictor of outcome in short-term (30-day) mortality in patients with ischemic stroke.
How to predict a difficult airway
Authors: Mekiš Dušan 
Published: February 2023

According to The American Society of Anaesthesiologists Task Force, a difficult airway is defined as a clinical situation in which a conventionally– trained anaesthesiologist experiences difficulty with face mask ventilation and/or difficulty with tracheal intubation. Failing at efficient airway management is a source of major apprehension for physicians. Predicting difficult airway management is a mandatory part of clinical practice for paediatric and adult patients so as to avoid unexpected difficult airway management and adverse outcomes. Predicting a difficult airway is based on a focused medical history, review of prior medical records, physical examination, and specific tests for airway assessment. Each feature or airway test has its own sensitivity and specificity for the prediction of a difficult airway. All airway assessment tests are characterised by low sensitivity, reasonable specificity, and a low positive predictive value. Several scoring system models have been developed by multivariate analysis with multiple different integrated tests or risk factors to improve the prediction of a difficult airway, but with considerably different effectiveness to predict a difficult airway. According to the European Society of Anaesthesiology, systematic multimodal screening before airway management should include the Mallampati classification and thyromental distance, mouth opening or interincisor distance, range of motion of head and neck, compliance of the mandibular space, and the upper lip bite test.