bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance analysis of ICI self-cancellation schemes in OFDM systems
Authors: Goel Ashish 
Published: April 2023

Abstract
Orthogonal frequency division multiplexing (OFDM) is a promising technique in modern high data rate wireless communication system. However, the serious problem in OFDM system is the inter-carrier-interference (ICI) that is produced by the carrier frequency offset (CFO). CFO destroys the orthogonal properties among the sub-carriers and introduces ICI. ICI is a major impairment in OFDM system as it can degrade the bit error rate (BER) performance of the system. In this paper we have proposed an optimal ICI self-cancellation scheme that can maximize the carrier-to-interference-ratio (CIR) of the system. This scheme is based on optimizing the data allocation and combining parameters where, for estimated CFO, the optimized values of these parameters are calculated using Nelder Mead simplex algorithm. An approach to calculate the sub-optimized values of data allocation and combining parameters is also proposed, where the knowledge of CFO estimation can be avoided. In this paper, we have carried out the complete performance analysis of ICI self-cancellation schemes. We have also derived the mathematical expressions for ICI coefficients and presented a comparative analysis of standard OFDM system with different ICI cancellation schemes. The mathematical expressions for CIR and BER performance are further derived. To confirm the validity of the results Monte Carlo simulations using Matlab are also performed. We have also done the comparison of peak-to-average power ratio (PAPR) of conventional ICI self-cancellation scheme and proposed scheme.
The influence of water vapor on the structural response of asphalt pavement
Authors: Zhang Youhua , Fang Xiaobin , Tan Xianfeng , Li Zhengang 
Published: April 2023

Abstract
A series of water damage phenomena of asphalt pavement during service show that water is very important. To comprehensively analyze the influence of water vapor factors on the response of pavement structure, this article first tests the water vapor diffusion coefficient of asphalt pavement materials at different temperatures establishes the water vapor concentration field model of the pavement structure, and analyzes the actual water vapor distribution of the pavement structure; then, the relationship between viscoelastic parameters of the mixture and water vapor concentration is established. Based on this, the finite element model of the pavement structure considering the water vapor factor is established, and the influence of the water vapor factor on the pavement structure response and fatigue life is quantified. It is found that water vapor has an important influence on the mechanical response. On the hottest days in summer, the attenuation of surface modulus caused by water vapor has the greatest impact on the upper layer of the pavement structure. Under the influence of water vapor, the position just below the wheel of the upper layer at the bottom of the horizontal tension strain increases by 108.26%, and the horizontal tension strain of the other layers increases by about 5%, increasing the risk of upper layer cracking. At the same time, water vapor reduces the stress that can be borne by the surface layer, while the rest of the stress is borne by the base. Compared with the fatigue life calculation method in the specification, the actual non-uniform water vapor concentration field reduces the fatigue life of the surface layer by 12.246%. This shows that the current structural calculation does not consider the water vapor factor, which makes the pavement structure more dangerous, and the influence of the water vapor factor should be fully considered.
Das Verhältnis geschriebener und gesprochener Sprache im 18. Jahrhundert am Beispiel der Interpunktion in Sprache und Musik
Authors: Schweitzer Claudia 
Published: April 2023

Abstract
The oral realization of written punctuation basically brings two parameters into play: rhythm and intonation. The former is visualized in writing the typeface by a space, while the latter is determined by conventions and depends on the speaker’s personal means of expression. In the 18th century, the oral realization of punctuation was only marginally addressed in grammars. Additional sources can be found in the area of music history, because the music theorists of the 18th century discussed the connection between language and music with great interest.
In this essay, prosodic models for the oral (audible) realization of punctuation marks are examined by comparing the current prosodic description of German with the musical analyses of Johann Mattheson and the remarks in the grammars of his time. Then baroque music examples are examined from the point of view of the possibility of refining the theoretical models. The aim of this interdisciplinary approach is to make use of ancient sources, both theoretical and practical, for the reconstruction of the prosody of 18th century German.
Wir beide und

мы с вами (‚wir mit Ihnen‘): Strategien zur Vagheitsreduktion im Gebrauch des Personalpronomens der 1. Person Plural in deutschen und russischen Diagnosemitteilungs- und Therapieplanungsgesprächen
Authors: Mostovaia Irina , Fedorovskaya Victoria , Imo Wolfgang 
Published: April 2023

Abstract
This paper examines the strategies doctors use to disambiguate the referential scope of the personal pronoun we. In clinical practice, doctors have to manage the different roles in which they can interact with the patients, – as individuals, as representatives of their clinic or their clinical department or as members of the scientific community of medical experts. These different roles also combine with different degrees of agentivity and responsibility. Patients therefore have to decode whether they are included into the we or not. Based on a corpus of more than 90 therapy planning talks recorded at German and Russian oncological clinical departments, our empirical study analyzes which strategies doctors employ to locally clarify the range of we, e. g., by adding a numeral (we two) or a locative phrase (we in this clinic) in order to ensure mutual understanding.
Berberine may provide redox homeostasis during aging in rats
Authors: Yadawa Arun Kumar , Srivastava Parisha , Singh Akanksha , Kesherwani Rashmi , Bhoumik Sukanya , Kumar Raushan , Arya Jitendra Kumar , Rizvi Syed Ibrahim 
Published: April 2023

Abstract
Aging is a natural phenomenon, which is characterised by progressive physiological changes at cellular and organ level. During aging, the defence mechanism of an organism declines over the period of time. The aim of this study was to investigate the biological efficacy of berberine in D-galactose induced aging rat models. For the study, rats were divided into four groups: Control received only vehicle, BBR received berberine orally, D-Gal received D-galactose subcutaneously and BBR + D-Gal received D-galactose and berberine simultaneously. D-galactose treatment increased the pro-oxidants such as malondialdehyde (MDA) level, protein carbonyl, plasma membrane redox system (PMRS) and advanced oxidation protein products (AOPP) in the erythrocytes or plasma. It reduced the anti-oxidant level such as reduced glutathione (GSH), ferric reducing ability of plasma (FRAP), plasma thiols, sialic acid and membrane transporters like Na+/K+ ATPase and Ca2+ ATPase activity in the erythrocyte membrane. Co-treatment of berberine in D-galactose induced aging rat models restored pro-oxidants and anti-oxidants in erythrocytes. Berberine also restored the activity of Na+/K+ ATPase and Ca2+ ATPase in the erythrocyte membrane. On the basis of these findings, we suggest that berberine treatment could attenuate erythrocyte aging in rats through stabilisation of the redox equilibrium.
Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length
Authors: Walker Courtney K , Greathouse Kelsey M , Tuscher Jennifer J , Dammer Eric B , Weber Audrey J , Liu Evan , Curtis Kendall A , Boros Benjamin D , Freeman Cameron D , Seo Jung Vin , Ramdas Raksha , Hurst Cheyenne , Duong Duc M , Gearing Marla , Murchison Charles F , Day Jeremy J , Seyfried Nicholas T , Herskowitz Jeremy H 
Published: April 2023

Proteomic studies utilizing postmortem human brain tissue samples have yielded robust assessments of the aging and neurodegenerative disease(s) proteomes. While these analyses provide lists of molecular alterations in human conditions, like Alzheimer’s disease (AD), identifying individual proteins that affect biological processes remains a challenge. To complicate matters, protein targets may be highly understudied and have limited information on their function. To address these hurdles, we sought to establish a blueprint to aid selection and functional validation of targets from proteomic datasets. A cross-platform pipeline was engineered to focus on synaptic processes in the entorhinal cortex of human patients, including controls, preclinical AD, and AD cases. Label-free quantification mass spectrometry data (n=2,260 proteins) was generated on synaptosome fractionated tissue from Brodmann area 28 (n=58 samples). In parallel, dendritic spine density and morphology was measured in the same individuals. Weighted gene co-expression network analysis was used to construct a network of protein co-expression modules that were correlated with dendritic spine metrics. Module-trait correlations were used to guide unbiased selection of Twinfilin-2 (TWF2), which was the top hub protein of a module that positively correlated with thin spine length. Using CRISPR-dCas9 activation strategies, we demonstrated that boosting endogenous TWF2 protein levels in primary hippocampal neurons increased thin spine length, thus providing experimental validation for the human network analysis. Collectively, this study describes alterations in dendritic spine density and morphology as well as synaptic proteins and phosphorylated tau from the entorhinal cortex of preclinical and advanced stage AD patients.Significance Statement:Proteomic studies can yield vast lists of molecules that are altered under various experimental or disease conditions. Here, we provide a blueprint to facilitate mechanistic validation of protein targets from human brain proteomic datasets. We conducted a proteomic analysis of human entorhinal cortex samples spanning cognitively normal and Alzheimer's disease cases with a comparison of dendritic spine morphology in the same samples. Network integration of proteomics with dendritic spine measurements allowed for unbiased discovery of Twinfilin-2 as a regulator of dendritic spine length. A proof-of-concept experiment in cultured neurons demonstrated that altering Twinfilin-2 protein level induced corresponding changes in dendritic spine length, thus providing experimental validation for the computational framework.
Multiple Subthreshold GPCR Signals Combined by the G-Proteins Gαqand GαsActivate theCaenorhabditis elegansEgg-Laying Muscles
Authors: Olson Andrew C. , Butt Allison M. , Christie Nakeirah T.M. , Shelar Ashish , Koelle Michael R. 
Published: April 2023

Individual neurons or muscle cells express many G-protein-coupled receptors (GPCRs) for neurotransmitters and neuropeptides, yet it remains unclear how cells integrate multiple GPCR signals that all must activate the same few G-proteins. We analyzed this issue in theCaenorhabditis elegansegg-laying system, where multiple GPCRs on muscle cells promote contraction and egg laying. We genetically manipulated individual GPCRs and G-proteins specifically in these muscle cells within intact animals and then measured egg laying and muscle calcium activity. Two serotonin GPCRs on the muscle cells, Gαq-coupled SER-1 and Gαs-coupled SER-7, together promote egg laying in response to serotonin. We found that signals produced by either SER-1/Gαqor SER-7/Gαsalone have little effect, but these two subthreshold signals combine to activate egg laying. We then transgenically expressed natural or designer GPCRs in the muscle cells and found that their subthreshold signals can also combine to induce muscle activity. However, artificially inducing strong signaling through just one of these GPCRs can be sufficient to induce egg laying. Knocking down Gαqand Gαsin the egg-laying muscle cells induced egg-laying defects that were stronger than those of a SER-1/SER-7 double knockout, indicating that additional endogenous GPCRs also activate the muscle cells. These results show that in the egg-laying muscles multiple GPCRs for serotonin and other signals each produce weak effects that individually do not result in strong behavioral outcomes. However, they combine to produce sufficient levels of Gαqand Gαssignaling to promote muscle activity and egg laying.SIGNIFICANCE STATEMENTHow can neurons and other cells gather multiple independent pieces of information from the soup of chemical signals in their environment and compute an appropriate response? Most cells express >20 GPCRs that each receive one signal and transmit that information through three main types of G-proteins. We analyzed how this machinery generates responses by studying the egg-laying system ofC. elegans, where serotonin and multiple other signals act through GPCRs on the egg-laying muscles to promote muscle activity and egg laying. We found that individual GPCRs within an intact animal each generate effects too weak to activate egg laying. However, combined signaling from multiple GPCR types reaches a threshold capable of activating the muscle cells.
Role of Parents’ Perceived Risk and Responsibility in Deciding on Children’s COVID-19 Vaccination
Authors: Liu Ying , Bruine de Buin Wändi , Kapteyn Arie , Szilagyi Peter G. 
Published: April 2023

OBJECTIVES
We examined associations between parents’ reports for whether their children had been vaccinated against coronavirus disease 2019 (COVID-19) and parents’ perceptions of the vaccine’s long-term risk, as well as their own sense of responsibility on deciding to vaccinate or not vaccinate their children.

METHODS
During the period when the Omicron variant was dominant (February–March 2022), we surveyed parents from a nationally representative, probability-based Internet panel about vaccination of their school-aged children, perceptions that the vaccine’s long-term risk exceeds risks without vaccination (henceforth: comparative long-term risk), their tendency to feel more responsible if their child became sick from vaccination than when unvaccinated (henceforth: anticipated responsibility), and their own vaccination status. We used multivariate analyses to assess associations of children’s COVID-19 vaccination with parental comparative long-term risk perceptions, anticipated responsibility, parents’ vaccination status, and demographics.

RESULTS
Among 1715 parent respondents (71% of eligible), 45% perceived vaccine-related comparative long-term risk and 18% perceived greater anticipated responsibility from vaccination than no vaccination. After accounting for parental vaccination, parents who were more concerned about comparative long-term risk and who reported greater anticipated responsibility were 6% (95% confidence interval, −0.09 to −0.03; P &lt; .001) and 15% (95% confidence interval, −0.19 to −0.11; P &lt; .001) less likely to have vaccinated their children, respectively. Findings were driven by vaccinated parents.

CONCLUSIONS
Parents’ perceptions of the COVID-19 vaccine’s long-term comparative risk and their greater anticipated responsibility for children getting sick if vaccinated (versus not) were associated with lower vaccine uptake among children of vaccinated parents.
Tafsir ‘Aqa'idi dalam Kajian Baru
Authors: Agustin Kartini Fujiyanti , Rahman Nida Al , Zulaiha Eni 
Published: April 2023

Tulisan ini mencoba menelaah lebih lanjut mengenai tafsir ‘aqa>idi> dengan menjelaskan sejarah kemunculan corak ‘aqa>idi> dalam dunia tafsir al-Quran, batasan istilah pembahasannya, akseptabilitas para ulama serta contoh kitab-kitab tafsir bercorak ‘aqa>idi>. MetodeNyang digunakanndalam penelitiannini adalahndeskriptif analisisnberbasis penelitiannkepustakaan dengannpendekatan sejarah dan tafsir. Temuan dari penelitian ini bahwa Tafsir ‘Aqa>idi> merupakan salah satu nuansa penafsiran yang menggunakan teori-teori dan pendekatan Teologis. Sejarah kemunculan corak teologis ini bermula pada setelah terjadi perangnSiffin antarankelompok Alinbin Abi Thalibndengan Muawwiyahnbin AbunSufyan. Adapun batasan istilah tafsir ‘aqa>idi> mencakup pembahasan yang berkenaan dengan teologi ketuhanan dan politik kepemimpinan karena keduanya merupakan tema penting yang menyangkut ideologi sekte. Dalam akseptabilitasnya, para ulama memberikan beberapa syarat yang dapat mengklasifikasikan tafsir ‘aqa>idi> dapat diterima ataukah tidak, diantara indikasi sebuah tafsir ‘aqa>idi> tidak dapat diterima adalah jika upaya penafsirannya terindikasi oleh hawa nafsu melegitimasi kelompoknya. Kitab-kitab tafsir bercorak ‘aqa>idi> dapat ditemukan dalam Tafsirnal-Kasysyaf karyanal-Zamakhsyarinyang bernuansanakidah Muktazilah, TafsirnMafatihnal-Ghaib karyanFakhruddinnAl-Razi yangnbermadzhab Asy’ariyyah serta Tafsir Al-Mizan yang ditulis oleh seorang tokoh Syiah, Husein Thabathaba’i.
Quando o ataque é o programa: as estratégias de campanha de Donald Trump e de Jair Bolsonaro no Twitter
Authors: Iasulaitis Sylvia , Vieira Aiane Oliveira 
Published: April 2023

O objetivo desta pesquisa é analisar o uso do microblog Twitter pelos candidatos vitoriosos nos pleitos presidenciais norte-americano em 2016, Donald Trump, e brasileiro em 2018, Jair Bolsonaro. A finalidade é identificar as estratégias utilizadas por ambos os candidatos a partir de uma investigação empírica e comparada por meio de parâmetros e variáveis operativas, buscando verificar especificidades e regularidades a partir de pares relacionais. A estratégia metodológica adotada é quanti-quali, fazendo uso da técnica de análise de conteúdo para classificar as mensagens em categorias que posteriormente foram analisadas de forma qualitativa, buscando inferir as estratégias de campanha adotada. Os resultados mostram que os candidatos privilegiaram a utilização de estratégias de campanha negativa e de ataque, posicionados no espectro ideológico da “extrema direita”.
NUCLEAR COMMUNICATIVE FUNCTION AS TEACHING STRATEGY FOR GERMAN MODAL PARTICLES: RELEVANCE OF THE MINIMALIST APPROACH
Authors: Aquino Marceli 
Published: April 2023

This work aims to introduce a proposal for teaching and learning German Modal Particles (MP) through their nuclear communicative functions. By having a highly structured internal paradigmatic organization, the minimalist approach considers each particle as having a specific communicative function, wherein their pragmatic meaning must be retrieved both by the recognition of their nuclear function, as well as by the interpretation of the communicative situation (AQUINO, 2023; DIEWALD, et al. 2017). Despite being of great importance for everyday interaction in German, MPs are rarely properly addressed in the context of German as an additional language (GAL) (AQUINO, 2020). In light of the experience in an extension course with teachers of GAL in Brazil, we argue that the description of the nuclear functions of MPs represents an innovative, objective and reliable tool for teaching of these modal elements in beginners to more advanced groups of students. As a didactic proposal we present: (i) a descriptive table with the nuclear functions of 15 MPs; (ii) a practical application of teaching MPs through their nuclear functions within authentic uses of doch and ja. Considering the gap of suitable didactic materials for teaching MPs, this proposal represents a significant contribution for GAL.
Cluster Based Communication In Wsn: A Survey
Authors: Et. al. Swati Juneja, , Et. al. Swati Juneja, 
Published: April 2023

WSN establishes an essential role in industrial applications. WSN consists of multiple tiny sensor nodes (SNs), which are organized in an outlying area.These sensor nodes consist of battery and thus it’s very challenging to interchange these SNs in a brassy environment once deployed.Therefore, in order to increase the network life, the sensor node energy needs to be preserved. Thus, in some protocols these wsn’s nodes grouped to form a cluster for efficient communication. In hierarchical approach,there aretwo concepts- one based on cluster and other one based on grid concepts. In cluster-based concepts, SN’s assembled to form clusters, where nodes having more residual energy become a leader of the cluster and thus known as Cluster Head. Thus, the network is separatedinto virtual grids in case of a grid based concept. This paper discusses the hierarchical routing protocol, its design challenge andan advantages and disadvantages of protocols.
Locating Operational Events of the Cooling Tower of a Nuclear Reactor with a Very Local Seismic Network
Authors: Chai Chengping , Marcillo Omar , Maceira Monica , Young Chris , Karnowski Thomas 
Published: April 2023

ABSTRACT
Geolocation of emergent seismic signals is challenging at close distances. We used three-component data from a seismic network and a targeted experiment at a research nuclear reactor to locate seismic sources. Utilizing known events collected during the targeted experiment, we were able to infer source locations with seismic amplitudes and polarization characteristics of the data. Although the resolution of the source location is not perfect, the seismic amplitudes and polarization analysis offer useful constraints. For the known events, the source region inferred with our analysis includes the true source locations. Synthetic tests indicate the resolution is largely due to limited data coverage and measurement uncertainties because the synthetic tests show similar results compared with the field data. We identified the source of the unknown event through spectrum cross correlation between the signals from the known events and an unknown event. Our findings were confirmed by operational staff at the facility. When the propagation medium properties (i.e., seismic velocity and quality factor for attenuation) are known, our analysis can be applied to continuous data from a seismic array to infer both source amplitude and location. If the medium properties are not known, a targeted experiment can be conducted to estimate them.