bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clouds across the new dawn for clinical, diagnostic and biological data: accelerating the development, delivery and uptake of personalized medicine
Authors: Horgan Denis , Capoluongo Ettore , Dube France , Trapani Dario , Malapelle Umberto , Rovite Vita , Omar Muhammad Imran , Alix-Panabières Catherine , Rutkowski Piotr , Bayle Arnaud , Hackshaw Allan , Hofman Paul , Subbiah Vivek 
Published: April 2023

Abstract
Growing awareness of the genetic basis of disease is transforming the opportunities for improving patient care by accelerating the development, delivery and uptake of personalised medicine and diseases diagnostics. This can mean more precise treatments reaching the right patients at the right time at the right cost. But it will be possible only with a coherent European Union (EU) approach to regulation. For clinical and biological data, on which the EU is now legislating with its planned European Health Data Space (EHDS), it is crucial that the design of this new system respects the constraints also implicit in the testing which generates data. The current EHDS proposal may fail to meet this requirement. It risks being over-ambitious, while taking insufficient account of the demanding realities of data access in daily practice and current economics/business models. It is marred by imprecision and ambiguity, by overlaps with other EU legislation, and by lack of clarity on funding. This paper identifies key issues where legislators should ensure that the opportunities are not squandered by the adoption of over-hasty or ill-considered provisions that jeopardise the gains that could be made in improved healthcare.
Characterisation of carbonate lake sediments as a potential filler for polymer composites
Authors: Borkowski Grzegorz , Martyła Agnieszka , Dobrosielska Marta , Marciniak Piotr , Głowacka Julia , Pakuła Daria , Gabriel Ewa , Przekop Robert E. 
Published: April 2023

Abstract
The purpose of the study was to determine whether lake sediments could be a potential raw material for the plastics industry. The examined samples were obtained in a complex process of sediment collection from Lake Swarzędzkie located in the region of Wielkopolska, Poland, followed by granulometric analysis by sieving and quartz grain shape analysis, with preparation of geotechnical sheets. The works involved the examination of physico-chemical characteristics of carbonate lake sediments and the analysis of impact of the sediments’ depth extraction on their chemical composition and physico-chemical properties. The lake sediment consists mainly of calcium carbonate (CaCO3) and can be a potential filler for plastics. Tests were carried out to determine chemical composition of the sediments and their thermal stability. The thermogravimetric analysis showed the three stages of the thermal decomposition. Sediments in deeper layers of the lake are characterised by the presence of not only CaCO3 and silica, but also other chemical compounds, including aluminosilicates. In addition, as the depth increases, the average size of sediment particles changes, with the main fraction particle size being the smallest for the material from the 6–12 m depth. Additionally, carbon content systematically decreases with increasing depth.
Physical Geodesy by Martin Vermeer published by Aalto University Press 2020
Authors: Eshagh Mehdi 
Published: April 2023

Abstract
The book “Physical Geodesy” by Martin Vermeer is written in a proper pedagogic way with a simple and complete text, good examples, conceptual questions and excellent exercises at the end of each chapter. This book is a suitable reference for educational purposes in Physical Geodesy from the bachelor to higher levels of education.
On the connection of the Ecuadorian Vertical Datum to the IHRS
Authors: Carrión José L. , de Freitas Sílvio R. Correia , Barzaghi Riccardo 
Published: April 2023

Abstract
In this work, the determination of the discrepancy between the Ecuadorian Vertical Datum (EVD) and the International Height Reference System (IHRS) is presented. The vertical offset was estimated at the EVD based on the fixed geodetic boundary value problem approach. The focus of the experiment was the determination of the anomalous potential in the EVD, which in turn enable determination of the respective geopotential value. Taking a geopotential space-based approach, two estimates of the EVD offset with respect to the IHRS were obtained that amount to −1.51 and −1.61 m2/s2.
Cultural competency training for the social service professions: A systematic literature review
Authors: Uher Alyssa , Fisher Marisa H. , Josol Cynde K. 
Published: April 2023

Abstract
Social justice movements have sought public awareness and positive change for marginalized communities, including the intersection of Black, Indigenous and People of Color (BIPOC) and disabled students. Despite significant strides made to decrease the inequities experienced by marginalized communities, gaps still exist. Increasingly, the fields of special education and related services (e.g., social services providers who support disabled students in schools) have been encouraging and requiring their practitioners to be taught culturally relevant content, such as cultural competency. Despite the push to incorporate cultural competency training, no systematic approach to providing this training has been identified. The current systematic literature review was conducted to identify common practices for training cultural competency within social service professions. A search across five databases yielded 53 studies that met inclusion criteria. The results demonstrate that cultural competency content and knowledge is taught and measured using a variety of methods and assessments; cultural competency was most often taught within academic programs and assessed using the Multicultural Counseling Inventory. This review contains a variety of methods that have been shown to teach cultural competency and thus can be used by educational programs and organizations across the social service professions to aid in creating trainings for their practitioners.
Honeycomb-like aluminum antennas for surface-enhanced infrared absorption sensing
Authors: Najem Melissa , Carcenac Franck , Coutaud Luka , Mouhibi Mohamed , Taliercio Thierry , Gonzalez-Posada Fernando 
Published: April 2023

Abstract
Surface-enhanced infrared absorption (SEIRA) spectroscopy is a competent method to detect trace quantity of molecules and even protein conformational flexibility by enhancing their vibrational modes. To improve the spectroscopy features, we propose a surface with honeycomb-like (HC) arrangement of aluminum equilateral triangles within a metal-insulator-metal configuration. With adjustable geometric parameters, the HC nanoantennas allow a tunable and wide spectral coverage in the IR. The reflectance measurements correlate extremely well with the numerical simulations. Being compact and insensitive to the light polarization, the HC are appealing for boosting the signal-to-noise ratio and increasing the number of hotspots as required for sensing applications. These nanoantennas are thus suitable for accurate and broadband SEIRA sensing via a spectral overlap between the large plasmonic resonances and the narrow IR vibrational modes of our analyte (vanillin). In line with our previously studied bowties nanoantennas, we demonstrate, using HC, SEIRA enhancement factors greater than 107 achieved at a tuning ratio below 1 stating the best spectral overlap. Around 104 molecules are sensed per HC tip. The investigation results are matching the best-reported SEIRA studies. These findings pave the way toward sensitive, adaptable, and miniaturized IR spectroscopy devices for vital applications like biosensing and environmental monitoring.
An efficient flow control technique based on co-flow jet and multi-stage slot circulation control applied to a supercritical airfoil
Authors: Wang Lei , Lu Hanan , Xu Yue , Li Qiushi 
Published: April 2023

Abstract
Circulation control is a kind of efficient flow control technology which can improve aircraft aerodynamic performance and reduce fuel consumption. However, improving the aerodynamic efficiency of a circulation device to enhance flight endurance and achieve environmentally flying is a challenging problem for the application of circulation control. This paper presents an efficient flow control technique that combines co-flow jet and multi-stage slot circulation control. The combinational flow control technique is applied to a supersonic airfoil to test its energy consumption and aerodynamic benefit achievement. Results show that both the single and double slot circulation control can improve the maximum lift-drag ratio of the baseline airfoil, with an increment of 11.3% and 19.1%, respectively. Compared with the single application of co-flow jet control which can increase the lift-drag ratio of the baseline airfoil by 16.3% and extend the stall angle of attack from 6° to 8°, the combinational flow control can obtain a more significant lift-drag ratio increment by about 27.3% and eliminate flow separations at high angle of attack. The stall angle of attack can even be increased to about 10°. Additionally, the blowing efficiency of the circulation control airfoil has been comprehensively analyzed. The results show that the maximum effective lift-drag ratio and highest blowing efficiency can be achieved at a blowing coefficient of 0.00235.
Differential equations of oscillation of thin plates with point bonding
Authors: Berikkhanova Gulnaz , Zholymbayev Oraltay , Aniyarov Almir 
Published: April 2023

AbstractThe relevance of the research results presented in this article lies in the general concept of elasticity theory, which integrates the bases of theoretical-empirical physics, practical mathematics and the natural implementation of modelling results in the fields of industrial (to a large extent in the design and manufacture of aircraft and naval aircraft shells and fuselages), construction (more so in the design and formation of multi-layer building structures), electronics and other areas of the science and industry complex. The aim of the study is to form a mathematical model of thin plate vibration based on a system of differential equations for the computational case of point bonding. The method of scientific search (Multilocal Literature Review) is used to achieve the set goal, which made it possible to establish the actual scientific-theoretical basis of the investigated problem, the method of mathematical modelling allowing to systematize the systems of differential equations developed earlier and formed in the framework of the present study, both for the general concept of the theory of elasticity of thin plates and for a selected calculation situation with partial constraints in the form of point bond imposing. As a result of the investigations conducted in the framework of this study, a mathematical model of the oscillations of thin plates bounded by special point-coupling conditions has been obtained, consisting of a system of differential equations obtained by successive iterations of mathematical transformations for the generated local boundary conditions. The mathematical model obtained is of practical scientific interest. The developed model environment forms a complete mathematical theory of elasticity for the formulated problem of the oscillatory process of thin plates with bounding point couplings. This problem has not received a satisfactory mathematical apparatus because of the complexity and cumbersomeness of analytical methods to describe the investigated elastic object.
Mixed micellization analysis of tri-substituted SAIL and amphiphilic drug mixture in aqueous/salt media at diverse temperatures
Authors: Kaur Ramanjeet , Kaur Gagandeep , Sharma Pooja , Kumar Harsh , Kaur Jasmeet 
Published: April 2023

Abstract
The present work aimed to study the mixed micellar behaviour of a tri-substituted imidazolium based surface-active ionic liquid (SAIL), 1-tetradecyl-2,3-dimethylimidazolium bromide [C14bmim][Br], with a drug Nortriptyline hydrochloride (NOT) in the water/salt (Na2SO4) medium using surface tension measurements (298.15 K) alongwith conductivity measurements (298.15K–313.15K). Lower experimentally obtained cmc values compared to their ideal values suggest that the investigated amphiphiles interact strongly. The values of micellar mole fraction (X
1) based on the several proposed models (Rubingh, Motomura, and Rodenas) and the ideal micellar mole fraction (X

id
) were assessed, and the predicted outcomes indicate that NOT has a significant contribution to the formation of mixed micelles, which increases as the [C14bmim][Br] mole fraction is increased. The negative values of micellization’s Gibbs free energy (ΔGm
0) between the examined amphiphiles were an indication of spontaneous mixed micelle formation. Micellar changes in entropy (ΔSm
0) and enthalpy (ΔHm
0) were also computed and discussed. Using surface tension measurements, surface-active parameters like surface tension at cmc (γ

cmc
), minimum surface area per IL molecule (A
min), maximum surface excess concentration (τ
max), effectiveness of surface tension reduction (π

cmc
), and cmc of mixed system have been estimated. The results showed an improved adsorption and micellization properties of these mixtures which will surely contribute to the tremendous rise of these mixed systems in drug delivery applications.
Histopathological findings on resected gastric specimens from obese patients undergoing laparoscopic sleeve gastrectomy
Authors: Mocian Flavius , Sorlea Sorin , Coroș Marius 
Published: April 2023

Background and aims. This study aimed to investigate the relationship between baseline characteristics of obese patients and histopathological findings on resected gastric specimens resulted after laparoscopic sleeve gastrectomy.
Methods. Seventy-seven patients undergoing laparoscopic sleeve gastrectomy in a university surgical department from Romania were included in the present study. Demographic data, preoperative Body Mass Index values, and their relationship with the histopathological findings of resected gastric specimens were statistically analyzed.
Results. The mean age of patients included was 40.2 ± 11.05 years and the mean Body Mass Index was 43.5 ± 7.8 kg/m2; 71.4% of the patients were female. Active chronic gastritis was the most common gastric pathology (39%) encountered. Helicobacter pylori infection was present in 27.2% of the cases. Normal gastric histology was found in 33.7% of the specimens. A strong statistically significant association was noted between Helicobacter pylori infection and active chronic gastritis (p<0.0001). Similarly, a statistically significant association was observed between age, Body Mass Index, and intestinal metaplasia (p=0.005 and p=0.009 respectively). No malignancies were found.
Conclusions. Our study results show that the incidence of active chronic gastritis and Helicobacter pylori infection is relatively high in obese patients. Considering this, we conclude that it is important to send the resected gastric specimens for histopathological analysis after laparoscopic sleeve gastrectomy.
Descriptions and Changes in Charge Master Pricings of US Children’s Hospitals From 2019 to 2021
Authors: Parlar-Chun Raymond , Samaniego Katelin , Jagen Adam , Forbes Ty , Zheng Norman 
Published: April 2023

BACKGROUND AND OBJECTIVES
A lack of price transparency may contribute to high healthcare costs. US hospitals were mandated to post their charge masters online in 2019. To compare changes in charge master prices of 3 common tests (complete blood count, complete metabolic panel, and chest radiograph) at US children’s hospitals between 2019 and 2021.

METHODS
Online search for charge master was conducted from July to December 2019 and October to December 2021. Descriptive statistics were reported for each test. Prices between years were adjusted for inflation and compared with paired t test. City-level variation was evaluated by comparing the coefficient of variation in 6 metropolitan areas: Baltimore, California Bay Area, Chicago, Dallas-Fort Worth, Los Angeles, and New York City.

RESULTS
Of 847 hospitals, charge masters were found in 747 (88%) in 2021 and 728 (86%) in 2019. Complete blood count prices ranged from $5 to $1037 in 2019 and $5 to $1085 in 2021, with no difference between the 2 years (P = .17). Complete metabolic panel prices ranged from $10 to $2440 in 2019 and $6 to $2746 in 2021, with no difference in prices (P = .75). Chest radiograph prices ranged from $20 to $1900 in 2019 compared with $30 to $5800 in 2021. Prices were higher compared with 2019 ($392 vs. $365, P &lt; .0006). City-level changes in the coefficient of variation showed only 2 cities with reduced coefficients of variation in all 3 tests.

CONCLUSIONS
Two years after mandating hospitals post charge masters online, there continues to be tremendous variability in prices of common tests across US children’s hospitals.
Disparities in Mortality Trends for Infants of Teenagers: 1996 to 2019
Authors: Woodall Ashley M. , Driscoll Anne K. , Mirzazadeh Ali , Branum Amy M. 
Published: April 2023

BACKGROUND AND OBJECTIVES
Although mortality rates are highest for infants of teens aged 15 to 19, no studies have examined the long-term trends by race and ethnicity, urbanicity, or maternal age. The objectives of this study were to examine trends and differences in mortality for infants of teens by race and ethnicity and urbanicity from 1996 to 2019 and estimate the contribution of changes in the maternal age distribution and maternal age-specific (infant) mortality rates (ASMRs) to differences in infant deaths in 1996 and 2019.

METHODS
We used 1996 to 2019 period-linked birth and infant death data from the United States to assess biennial mortality rates per 1000 live births. Pairwise comparisons of rates were conducted using z test statistics and Joinpoint Regression was used to examine trends. Kitagawa decomposition analysis was used to estimate the proportion of change in infant deaths because of changes in the maternal age distribution and ASMRs.

RESULTS
From 1996 to 2019, the mortality rate for infants of teens declined 16.7%, from 10.30 deaths per 1000 live births to 8.58. The decline was significant across racial and ethnic and urbanization subgroups; however, within rural counties, mortality rates did not change significantly for infants of Black or Hispanic teens. Changes in ASMRs accounted for 93.3% of the difference between 1996 and 2019 infant mortality rates, whereas changes in the maternal age distribution accounted for 6.7%.

CONCLUSIONS
Additional research into the contextual factors in rural counties that are driving the lack of progress for infants of Black and Hispanic teens may help inform efforts to advance health equity.
Karakteristik Mutu Fisik dan Hedonik Serbuk Ekstrak Ikan Gabus (Channa striata)
Authors: Wulansari Devi , Prasetyati Sukma Budi , Ratnaningtyas Susi , Anasri Anasri , Holis Nurur Rahmah 
Published: April 2023

Albumin berperan penting mengatur tekanan darah dalam pembuluh darah dan menjaga cairan yang terdapat dalam pembuluh darah tidak bocor ke jaringan tubuh sekitarnya. Ikan gabus mengandung albumin lebih banyak daripada ikan jenis lain. Stabilitas sediaan dalam bentuk cair cenderung kurang baik, tidak efisien, rasa obat yang tidak menyenangkan atau tidak enak dan menyebabkan penurunan mutu yang lebih besar dikarenakan mudahnya perkembangbiakan bakteri sehingga nilai nutrisinya menurun. Perlu dilakukan upaya untuk meningkatkan mutu yaitu dengan cara menyerbukan ekstrak ikan gabus. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik mutu fisik dan hedonik pada serbuk ekstrak ikan gabus dengan bahan pengisi laktosa pada konsentrasi yang berbeda. Ekstrak ikan gabus dikeringkan menggunakan laktosa dengan 2 kelompok konsentrasi A (25%) dan B (20%). Proses pengeringan dengan cara pendinginan dilakukan pada suhu 10˚C hingga kering. Pengujian yang dilakukan antara lain kadar albumin, uji waktu alir, uji sudut diam dan uji hedonik. Kadar albumin tertinggi terdapat pada kelompok A sebesar 0,207 mg/ml. Hasil uji waktu alir dan sudut diam menunjukan bahwa kelompok B memenuhi syarat granul dengan skor uji waktu alir sebesar 4.64 detik dan uji sudut diam sebesar 39,35˚. Uji hedonik menunjukkan kelompok A lebih disukai oleh panelis. Kelompok dengan konsentrasi ekstrak 25% memiliki karakter mutu yang lebih baik namun perlu perbaikan formulasi untuk meningkatkan kualitas mutu fisik produk.
Analysis of The Standard Quality of The Crude Solar Salt become The Health and Industry's Salt in Karawang District
Authors: Pasaribu Roberto Patar , Pranoto Aris Kabul , Tanjung Anasri , Waluyo Waluyo , Suratna Suratna 
Published: April 2023

"Krosok" salt, or "Crude Solar Salt", is salt produced through the evaporation and crystallization of seawater. Some krosok salts have different qualities, and this is influenced by the quality of seawater as raw material, available production facilities and post-harvest handling. This krosok salt is mainly produced by salt farmers along the north coast of Karawang Regency. This study aimed to determine the quality of krosok salt obtained from salt farmers in Karawang Regency and to raise salt quality standards to increase the sale value of salt by creating healthy and industrial salt products. The method is to re-crystallize the "krosok" salt by adding binders or additives. Based on the results of the salt crystal test in the laboratory, it is known that the crystallization of "krosok" salt in Karawang Regency has a NaCl content of up to 99.35%; this value is already above the SNI quality standard of 98% as health salt. Meanwhile, for hazardous materials such as (Hg) and (As), the content is around 0.001%, below the SNI threshold of 0.1%.
CONSTRUÇÃO DE REDES TEMÁTICAS
Authors: Azevedo Maria Antonia Ramos de , Costa Xavier Amanda Rezende , Morais Pâmela Christina Gonçalves de 
Published: April 2023

Atualmente, no ensino superior brasileiro, há uma crescente nos movimentos de reestruturação acadêmica que priorizam a inovação pedagógica e curricular dos cursos universitários, intensificados por políticas públicas e que se traduzem em projetos políticos-pedagógicos de curso que salientam o conceito de interdisciplinaridade e a indissociabilidade entre ensino, pesquisa e extensão. Neste contexto, a organização curricular intenciona a articulação dos diferentes conhecimentos através de eixos que permitam que o conhecimento se construa de maneira integral a partir das variadas epistemologias das áreas. Isto posto, este artigo tem por objetivo contribuir de maneira teórica e conceitual para a reflexão de estratégias teórico-metodológicas que colaborem com a promover de rupturas paradigmáticas no que concerne à inovação, a interdisciplinaridade, ao currículo e à criação de projetos que sejam balizados em uma perspectiva emancipatória. Trata-se de um estudo de caráter qualitativo que, sob a ótica da Pedagogia Universitária, discorre sobre os modelos de organização interdisciplinar no ensino superior e apresenta reflexões derivadas de oficinas pedagógicas realizadas com coordenadores de curso e professores universitários. É possível constatar que, para a elaboração de currículos interdisciplinares que se efetivem em projetos pedagógicos de curso estruturados e articulados por este preceito, é necessário definir um conjunto de princípios que devem orientar as decisões institucionais, bem como a clareza de que uma organização curricular potente e interdisciplinar excede uma visão disciplinar e/ou compartimentalizada de ensino superior.