bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Outcomes and Interprofessional Collaborative Practice in Telehealth Allied Health Community Services: A Prospective Observational Study
Authors: George Stacey , Brebner Chris , Berg Maayken van den , Champion Stephanie , Mills Arryn , Barr Chris , Briley Annette , Kakogianis Mirella , Mpundu-Kaambwa Christine 
Published: December 2022

AbstractBackground In Australia, Allied health community services delivered via telehealth rapidly expanded during the coronavirus pandemic (COVID-19). A gap exists in the understanding of outcomes and interprofessional collaborative practice in allied health community interdisciplinary telehealth services. The objectives of this study were to evaluate patient/service outcomes, cost-effectiveness and interprofessional collaborative practice in two allied health community services delivered via telehealth. One providing early intervention, and the other intervention for people with chronic conditions. Methods Quantitative data from client records (n = 15) and surveys (n = 16) were analysed descriptively. Qualitative data gained from: semi-structured interviews (n = 7) gathered client perspectives, and focus groups (n = 5) staff perspectives (n = 20), were analysed using Braun and Clarke’s six phases of reflexive thematic analysis. Results There was a non-significant improvement in Quality of life scores (Mean = 0.171) from 0.422 (SD = 0.565) at baseline to 0.593 (SD = 0.264) post-intervention, (p = 0.379). Clients incurred lower healthcare costs and had a clinically significant increase (≥ 2 points) in goal measure change scores (4.25) compared with pre-pandemic care. Three key themes were identified: 1. Focus on client-centred care and teamwork, 2. Adjustments to communication, 3. Value of face-to-face. Conclusions Community allied health services delivered via telehealth in COVID-19 can support interprofessional collaborative practice, improve client outcomes and achieve service efficiencies. Recommendations to maximise interprofessional collaborative practice include a focus on communication between clinicians and clients, and adapting interdisciplinary team processes to support service delivery via telehealth.
Impact of the COVID-19 Pandemic on Surgical Residency Training: Time to digitalization
Authors: Naouar Sahbi , Khlifa Badreddine Ben , Khribi Mayssa , Braiek Salem , Kamel Rafik El 
Published: December 2022

Abstract
Background
The COVID-19 pandemic has negatively impacted surgical residency training worldwide. This study aims to evaluate the impact of the COVID-19 pandemic on surgical residency training and psychological well-being in a Tunisian residents cohort, and to emphasize on the importance of digital simulation-based training through a review of different tools reported in the literature.
Methods
A cross-sectional survey of surgical residents was conducted at our surgical division of the teaching hospital, between 1st and 30 December 2020. A study-specific electronic questionnaire designed using the free software Google Forms was distributed to 36 residents via emails and Whatsapp.
Results
At the end of the study period, only 26 participants (72%) completed and submitted the questionnaire. Most respondents reported the negative impact of the pandemic on clinical and surgical training. Anxiety was noticed in all participants; more than half presented depression. During the pandemic, clinical activity was mainly based on "patient bedside" learning (50%) and college courses via webinars (38.4%). Surgical training was mainly based on the medico-surgical encyclopedia (65.4%), surgical videos on YouTube® (61.5%) and emergent surgeries attendance (53.8%). There was a lack of didactic teaching programs implementation during the pandemic.
Conclusions
There is a pressing need to improve surgical training during residency. Simulation-based training using digital tools is the best way to improve psychomotor skills outside of the operating theatre.
Assessing Empirical Support for Replicator Dynamics in Financial Markets: A Maximum Entropy Method Tested with America’s Largest Companies
Authors: Fort Hugo 
Published: December 2022

Abstract
The replicator dynamics (RD) model provides important insights in the evolution of markets but lacks empirical support. A main difficulty is how to obtain the payoff matrix connecting the pairwise effects between interacting market entities. A procedure for estimating these pairwise payoffs, based on the Maximum Entropy (ME) principle, is proposed. The resulting method is thus called Replicator Dynamics Pairwise Maximum Entropy (RDPME). To test this method, daily market values from 2014 to 2019 of America’s top revenue companies are used. As it is customary in time series forecasting analysis, these series are divided into a training period, used to infer the RDPME parameters (intrinsic growth rates and payoff matrix), and a validation period, used to validate the model. Different partitions into training and validation periods are considered. The RDPME method outperforms the stochastic benchmark of the geometric random walk in predicting empirical shares for most of the companies along most choices of validation periods.
JEL codes: C51, C52,C53, C55, C58, C63, G17
D'Alembert Wave Equation Misconception
Authors: N. Bharathraj G. 
Published: December 2022

Abstract
We analyse a simple one dimensional arrangement of identical springs coupled with identical masses to understand longitudinal oscillations on the spring-mass chain. D'Alembert wave eqn implies only one wave-speed value, there is no wave dispersion. Ab initio analysis of the normal modes suggests that wave-speed in a closed-chain has dispersion. In the open-chain case, we can realistically associate a wave-length and wave-speed only for about half the normal mode solutions, because the higher frequency half of the modes on open-chains do not have sinusoidal solutions. In the normal mode analysis we find sinusoidal variation of frequency wrt mode number, not linear as expected by the idea of harmonics. Framing of D'Alembert wave equation is untenable. It is purely a geometric construct without any Physics basis to it.
Okra transcription factor AeWRKY31 enhanced cold resistance of transgenic Arabidopsis through promoting ABA biosynthesis and inhibiting ROS production
Authors: Zhu Zhipeng , Yu Jian-Xiang , Liu Fang-Fang , Xiong Ai-Sheng , Sun Miao 
Published: December 2022

Abstract
The changing climate leads to frequent low temperature events, which results in lower crop production worldwide. Plant growth and development are regulated by WRKYs, as well as a variety of defense responses, including salt, drought, and extreme temperature stresses. Here, a transcription factor AeWRKY31 was obtained from Abelmoschus esculentus and ectopic expressed in Arabidopsis thaliana. Molecular localization and self-transactivation assays revealed AeWRKY31 was a nuclear-localized protein with self-transactivation property. Subsequently, AeWRKY31 expression activated the expression of AtABA1, AtABA2, and AtNCED6, and promoted endogenous ABA accumulation, which induced stomata closure of transgenic Arabidopsis. Histochemical staining and ROS content determination demonstrated that AeWRKY31 expression inhibited the accumulation of H2O2 and O2- and decrease electrolyte leakage in transgenic lines. Meanwhile, compared with that of WT, relative expression levels of cold response-related genes were up-regulated in transgenic lines. Finally, AeWRKY31 transgenic Arabidopsis plants exhibited enhanced cold tolerance both in vivo and in vitro experiments. Our findings will benefit molecular breeding and anti-cold mechanism investigation of okra.
Thioridazine Reverses Trastuzumab Resistance in HER2 Positive Gastric Cancer Cells Through Down-regulation of Skp2 Expression
Authors: Yang Zhengyan , Xue Jingrui , Wang Shuangfeng , Zhao Yiwei , Zhao Zhi , Niu Baohua , Ren Zhiguang , Hu Yanzhong , Shi Ming 
Published: December 2022

Abstract
As the only first-line targeted therapy for advanced gastric cancer (GC) with HER2-positive status, the efficacy of trastuzumab is limited by the high rates of primary and secondary resistance. The therapeutic effect of many other HER2-targeted drugs is not satisfactory in GC. Previous studies have demonstrated that overexpression of S-phase kinase-interacting protein 2 (Skp2) predicted poor prognosis of HER2-positive GC and promoted cancer cell proliferation, resistance, and glycolysis. It has been proved that trastuzumab-resistant GC cells exhibit high glycolytic activity. We found thioridazine restores the sensitivity of trastuzumab in vivo and in vitro by inhibiting Skp2 expression and glycolytic activity. Moreover, thioridazine combined with lapatinib also showed strong inhibitory effects on the growth and survival of trastuzumab-resistant GC cells. Collectively, these data introduce a thioridazine-based therapy to overcome trastuzumab resistance in GC.
Detection and ranging of small targets on water based on binocular camera and improved YOLOv5 algorithm
Authors: Li Yongguo , Xu Caiyin , Qin Can , Li Xiangyan , Tang Xuan 
Published: December 2022

Abstract
In order to meet the needs of intelligent ships to capture and grasp small targets while navigating on water and to be able to sense and avoid small targets, a water target detection method based on the YOLOv5-s algorithm is proposed, and the experimental equipment is allowed to perform real-time and high-precision target recognition and sensing in a dynamic water environment. This method uses the view acquisition by using the ZED 2i binocular camera, and the RGB images obtained by the binocular camera are used as the input of the feature fusion module to improve the YOLOv5-s algorithm to obtain the position information of the small target on water in the acquired image, and the relative position about the camera is calculated by combining the pixel position information obtained by the binocular camera. At the same time, in order to ensure the detection accuracy, the sample anchor frames of some datasets are updated according to the detection results; then the dataset is retrained; the images acquired through the binocular camera are corrected for distortion and stereo correction, etc., to make the detection accuracy higher; the experimental results show that the detection accuracy of combining the binocular camera with the improved YOLOv5-s algorithm is better than that of other methods for small target detection on water and better than the original algorithm The evaluation index map_0.5 is as high as 9.79%, and the detection accuracy error of the lateral detection of the target on water is kept at about 6.6%, and the lateral detection accuracy within 20 meters is about 8.7%. The obtained results can reliably provide a valuable basis for autonomous intelligent ships to work in complex water environment.
Prediction of Urban Water Demand Based on Improved PCA-SSA-Elman Dynamic Neural Network
Authors: ge qiang , WANG Liying , ZHAO Weiguo , GU Shixiang 
Published: December 2022

Abstract
In principal component analysis, data logarithm transformation and row vector centralization improvement are carried out, reducing the input, and simplifying the network model. Use sparrow search algorithm for optimization, and compare the performance with cuckoo algorithm, seagull algorithm, and whale algorithm. To avoid problems as slow convergence speed and insufficient exploration ability, an improved sparrow search algorithm integrating refraction inverse learning mechanism, sin-cosine and Cauchy variation is proposed, a high-precision PCA-SCSSA-Elman neural network prediction model is established. The results show that SSA-Elman neural network has the fastest convergence speed and the optimal performance value is 0.1391 higher. Combined with the extracted principal component data, compared with PCA-Elman, PCA-SSA-Elman and PCA-SineSSA-Elman prediction models, the mean absolute error is higher than the other three models [45.6850%, 14.9168%, 11.7448%], the prediction error is minimal. The results show that the improved sparrow search algorithm can significantly improve the convergence speed and optimization accuracy.
What does your partner want? Using a gender equality lens to assess partner support and involvement in Family Planning in Uganda
Authors: Olapeju Bolanle , Passaniti Anna , Odeke Paul , Hendrickson Zoé Mistrale , Nalukwago Judith , Mugabe Pallen , Bufumbo Leonard , Kimbowa Musa , Amado Fiona , Kayongo Emmanuel , Naibere Mabel , Nanyonga Nanah , Mkandawire Glory , Mugahi Richard , Bakyaita Tabley , Kabanda Richard , Storey Doug 
Published: December 2022

Abstract

Background: While partner involvement in health-related decision-making is linked with positive health behaviors, a key gap in the literature exists on how this construct should be measured and the specific ways men and women in Uganda perceive partner support in the context of family planning. The USAID-funded Social and Behavior Change Activity (SBCA) in Uganda explored the differences in male versus female priorities in the decision-making considerations and preferred measures of partner support related to family planning in order to design contextually relevant solutions.
Methods: Cross -sectional study using a nationally representative telephone survey among 1177 men and women aged 18-49 years old in sexual partnerships. Key measures included current family planning use (Are you or your partner currently doing anything to prevent or delay becoming pregnant?); family planning decision-making considerations (In your experience, which of the following are the three most important considerations as you make family planning decisions?); and preferred partner support (What level of involvement would you like to see from your partner in your family planning decisions?). Multivariable logistic regressions explored factors associated with decision-making priorities and preferred partner support, adjusting for sociodemographic confounders.
Results: Two-thirds (66%) of men and women wanted a high level of involvement from their partner, which was associated with higher odds of using family planning (aOR: 2.46, 95% CI: 1.87 - 3.24). Specific ways partners could be involved included accompanying them to health services (39%), permitting them to get family planning services (26%), and jointly discussing family planning options (23%). Of note, more women wanted their partner to accompany them (45%) than men (33%) while more men (29%) wanted to jointly discuss options than women (15%).
Conclusions: Partner support needs to be operationalized differently for men and women; therefore, social and behavior change (SBC) interventions should employ a gender lens when implementing family planning programs. The project used these insights to implement a health campaign that leverages the views of key audiences; explicitly encourages partner dialogue across the various life stages; and empowers women with knowledge and skills to have honest conversations with their partners about when to have children and how many to have.
Nanoplastics Detected in Commercial Sea Salt
Authors: Ruan Xuejun , Ao Jianpeng , Jones Robin , Liu Juan , Li kejian , Ge Qiuyue , Xu Guanjun , Liu Yangyang , Wang Tao , Xie Lifang , Gong Kedong , Wang Wei , Valev Ventsislav K. , Ji Minbiao , Zhang Liwu 
Published: December 2022

Abstract

People of all ages consume salt every day, but is it really just salt? Plastic nanoparticles (nanoplastics) polluting the oceans and the atmosphere are posing an increasing environmental threat and have begun to contaminate everyday salt in consumer goods. Herein, we developed a combined Surface Enhanced Raman Scattering (SERS) and Stimulated Raman Scattering (SRS) approach that can simultaneously realize the filtration, enrichment, and detection of nanoplastics in commercial salt. SERS was used to explore the potential types of nanoplastic contaminants in salts. SRS was used to conduct imaging and to quantify the presence of nanoplastics. Nanoplastics in sea salts produced from different sources were studied, with the following nanoplastics detected: polystyrene (PS), polyethylene (PE), polypropylene (PP). We estimate that, depending on location, an average person could be ingesting as many as 63,100 nanoplastics per year through the consumption of sea salt alone. Nanoplastics can readily adsorb organic matter and heavy metal particles, so the potential harm to human health should not be underestimated.
Ewing's sarcoma microenvironment-sensitive theranostic nanoprobe for image-guided drug delivery
Authors: Wang Yu , Wang Wenxiang , Yi Xinzeyu , Liu Changjiang , Zhang Hao , Wu Song , Liu Qiaoyun , Yu Aixi 
Published: December 2022

Abstract
To improve the specificity of the current diagnosis and treatment of Ewing's sarcoma (ES), efforts are underway to develop theranostic targeting probes. In particular, tumor specific markers and microenvironment represent potential targets. In addition, tumor exosomes are considered as possible nanocarriers for drugs to achieve tumor targeting and therapy. Herein, the development of CS2-YK@Exo, by packaging the pH-responsive ES-targeting near-infrared probe CS2-YK into ES exosomes is presented. The engineered exosome can serve as shuttle vehicles for drug uptake by tumor cells, and the pH-activatable characteristics of CS2-YK@Exo in acidic tumor environments can realize a precise image-guided drug delivery for the treatment of ES. The in vivo and in vitro studies verified the targeting, specificity, efficacy, and safety of the probe. Subcutaneous ES tumor mouse models, orthotopic models, and lung metastasis models are established to evaluate the real-time target imaging capabilities of the probe. This study demonstrates the potential of CS2-YK@Exo as a delivery nanosystem for tumor-targeted imaging and release of therapeutics to achieve real-time monitoring of therapy.
The effect of strabismus surgery performed by preserving the anterior ciliary vessels on the choroid in pediatric patients
Authors: Yetkin Ali Asgar , Şimşek Ali 
Published: December 2022

Abstract
Background: Horizontal strabismus surgery is one of the most common eye operations. Many studies have shown that strabismus surgery has an effect on choroidal thicknesses. This study aimed to evaluate choroidal changes after the anterior ciliary vessels (ACV) conservation surgery using Enhanced Depth Imaging-Optical coherence tomography (EDI-OCT).
Methods: This study included 41 eyes of 26 pediatric patients that were diagnosed with esotropia and underwent surgery with the standard procedure and 38 eyes of 25 pediatric patients treated with ACV preservation. Preoperative and postoperative refraction error measurements, biomicroscopic examinations, intraocular pressure measurements, dilated fundus control, and strabismus examinations were performed, and the best corrected visual acuity was determined. The patients were operated on under general anesthesia by the same surgeon using two different procedures: the standard procedure (Group 1) and by preserving the ACV (Group 2). Using EDI-OCT, choroidal measurements were performed preoperatively, on postoperative week 1, month 1, and month 3.
Results: The preoperative and postoperative choroidal thickness measurements of the patients in Group 1 decreased in all regions postoperatively (p<0.05) especially at week 1 and month 1, but approached the preoperative values at the third -month evaluations (p>0.05). In Group 2, there was no statistically significant difference in the choroidal measurements between the preoperative ​​and postoperative week 1, month 1, and month 3 values (p>0.05).
Conclusions: ACV preservation is recommended to prevent choroidal changes occurring in the early period after horizontal strabismus surgery.
Design and implementation of a carry-save full adder in quantum-dot cellular automata
Authors: Amiri Melika , Dousti Massoud , Mohammadi Majid 
Published: December 2022

Abstract
Adders are one of the most widely used circuits in microprocessors. These circuits can also be used in various arithmetic operators. Adders are generally made in standard CMOS technology. However, at the nanoscale, CMOS technology faces some issues, such as less control over the gate and high current leakage. Quantum-dot cellular automata (QCA) can be employed to implement the next generation of digital electronic circuits. The present study proposes a carry-save adder in QCA technology for the first time. To the best of our knowledge, no QCA-based carry-save adder has been designed and examined to date. The simulation results show the superior performance of the proposed design over the state-of-the-art ripple-carry adders, with at least two QCA clocks faster addition operation even in the worst-case scenario. The proposed QCA-based adder has significantly higher speed and lower power consumption than its CMOS-based counterpart. The manufacturability of the design is substantially improved. In addition, our proposed full adder requires only 62 cells and the proposed full adder–subtractor requires only 521 cells. The proposed full adder–subtractor occupies 0.62 µm2. A design and simulation tool for QCA-based circuits, QCADesigner, is used to analyze the proposed designs.
A Qualitative Exploration of the Predictors and Approaches of Misuse of Digital Media among Adolescents in Bangladesh: A Public Health Perspective
Authors: BakiBillah Abul Hasan 
Published: December 2022

Abstract
This study investigated the variables affecting the inappropriate use of digital media in Bangladesh with regard to sexual and reproductive health. Academics, researchers, officials, and activists were among the nineteen key informants who took part in the study's Key-Informant-Interview (KII). The transcripts of the interviews were analyzed thematically. The informants had at least a bachelor's degree, with a mean age of 40 (SD+/- 6.8) years. The main causes of the misuse of digital media in the forms of cyberbullying, sexting, revenge porn, sextortion, access to and production of porn videos, etc. were identified as being easy access to indecent (porn) websites, low self-awareness of girls when using social networking sites and other digital devices, the culture of injustice and the muscle-man phenomenon, parental negligence, and level of awareness. According to this study, women and girls are the main misuse victims, with becoming sex slaves and continuing to have persistent mental illnesses being the worst forms of victimization. The research advocated for a total prohibition of pornographic websites, more awareness among women and girls, prompt assistance from law enforcement, and, most importantly, parents' full care and attention.