bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Naturalistic Developmental Behavioral Interventions in Early Intervention for Autistic Toddlers: An Observational Study
Authors: Lee Jordan , Sone Bailey , Rooney Tara , Roberts Megan Y. 
Published: January 2023

Purpose:
Naturalistic developmental behavioral interventions (NDBIs) have demonstrated initial promise in facilitating social communication development for autistic toddlers, but their highly structured protocols may be a barrier toward their use by early intervention (EI) providers who must individualize intervention according to family-centered principles. This study aimed to characterize the extent to which EI speech-language pathologists (SLPs) use NDBI strategies, and the range of skills and behaviors addressed during their EI sessions, to contextualize the role of NDBIs within the scope of needs of families with autistic children in EI.

Method:
This observational study included 25 families with an autistic toddler and their EI SLP. One home-based session was recorded for each family, and an observational measure was used to describe SLPs' NDBI strategy use. Qualitative content analyses were also used to characterize the strategies SLPs recommended to families, and the child skills and behaviors they discussed.

Results:
SLPs did not implement NDBI strategies with high quality, but they implemented developmental NDBI strategies with significantly higher quality than behavioral NDBI strategies. SLPs discussed many strategies and skills across disciplines within the session.

Conclusions:
SLPs may require further training to implement NDBI strategies, but given the breadth and depth of skills addressed during sessions, researchers should investigate and report on the impact of NDBIs on a wider range of communication skills and developmental domains. This will facilitate clinical decision making and make these interventions better aligned with family-centered EI principles.

Supplemental Material:

https://doi.org/10.23641/asha.21834480
Embedding Executive Function Training Into Early Literacy Instruction for Dual Language Learners: A Pilot Study
Authors: Goodrich J. Marc , Peng Peng , Bohaty Janet , Leiva Sergio , Thayer Lauren 
Published: January 2023

Purpose:
Early literacy skills are key indicators of future reading development for young dual language learners (DLLs). Additionally, emerging evidence indicates that young children's executive function (EF) skills are uniquely associated with elementary school reading outcomes (Ribner et al., 2017). Therefore, the purpose of this pilot study was to evaluate the potential for embedding strategies to support EF development within evidence-based early language and literacy instruction for young DLLs.

Method:
Sixty-nine preschool DLLs were randomly assigned to one of three treatment groups: a business-as-usual control group (BAU), a group that received early literacy instruction only (EL group), and a group that received early literacy instruction with embedded EF strategies (EL + EF group). The intervention focused on improving children's early literacy skills, including letter–name knowledge, phonological awareness, and oral language. Children completed assessments of early literacy and EF immediately before and after the intervention.

Results:
The EL and EL + EF groups significantly outperformed the BAU control group for two early literacy outcomes, and effects of evidence-based early literacy instruction were strongest for children with poor EF skills. Results indicated that there were no significant differences between the EL + EF and EL groups.

Conclusions:
This pilot study indicated that there was no significant benefit to adding supports for EF skills within evidence-based early literacy instruction. Additional research is needed with larger samples to replicate observed effects.

Supplemental Material:

https://doi.org/10.23641/asha.21834465
A 1.0 fJ energy/bit single‐ended 1 kb 6T SRAM implemented using 40 nm CMOS process
Authors: Wang Chua‐Chin , Sangalang Ralph Gerard B. , Tseng I‐Ting , Chiu Yi‐Jen , Lin Yu‐Cheng , Jose Oliver Lexter July A. 
Published: January 2023

AbstractAn ultra‐low‐energy SRAM composed of single‐ended cells is demonstrated on silicon in this investigation. More specifically, the supply voltages of cells are gated by wordline (WL) enable, and the voltage mode select (VMS) signals select one of the corresponding supply voltages. A lower voltage is selected to maintain stored bit state when cells are not accessed, lowering the standby power. And when selecting a cell (i.e. WL is enabled) to perform the read or write (R/W) operations, the normal supply voltage is used. A 1‐kb SRAM prototype based on the single‐ended cells with built‐in self‐test (BIST) and power‐delay production (PDP) reduction circuits was realised on silicon using 40‐nm CMOS technology. Theoretical derivations and simulations of all‐PVT‐corner variations are also disclosed to justify low energy performance. Physical measurements of six prototypes on silicon shows that the energy per bit is 1.0 fJ at the 10 MHz system clock.
A PVT resilient true‐time delay cell
Authors: Yarahmadi Ahmad , Jannesari Abumoslem 
Published: January 2023

AbstractA true‐time delay (TTD) cell in TSMC 0.18 μm CMOS technology for 1–5 GHz applications is presented. Process variations, ageing effects, field variations, and other non‐idealities have some impacts on the TTD cell's devices. One of the vulnerable specifications of TTD cells is their delay variation. While the TTD cell works in a delay line, the cell must have a constant and robust delay in the frequency band. For this matter, the body bias technique is presented and applied to the inductor‐less TTD cell. With this technique, the threshold voltage can be manipulated intentionally. So, any variation in this voltage can be compensated with the body biasing of transistors. The simulation results show the TTD cell's robust performance against non‐idealities, while delay variation improves more than 3× times in the frequency band of interest. This TTD cell provides a 50.95 pS delay with only 2% variation, while S11 and S22 parameters are lower than −10 dB in the 1–5 GHz frequency band. IIP3 of the TTD cell is about 2.7 dBm, and the power consumption is 20.5 mW.
Context‐aware target classification with hybrid Gaussian process prediction for cooperative vehicle safety systems
Authors: Valiente Rodolfo , Raftari Arash , Mahjoub Hossein Nourkhiz , Razzaghpour Mahdi , Mahmud Syed K. , Fallah Yaser P. 
Published: January 2023

AbstractVehicle‐to‐Everything (V2X) communication has been proposed as a potential solution to improve the robustness and safety of autonomous vehicles by improving coordination and removing the barrier of non‐line‐of‐sight sensing. Cooperative Vehicle Safety (CVS) applications are tightly dependent on the reliability of the underneath data system, which can suffer from loss of information due to the inherent issues of their different components, such as sensors' failures or the poor performance of V2X technologies under dense communication channel load. Particularly, information loss affects the target classification module and, subsequently, the safety application performance. To enable reliable and robust CVS systems that mitigate the effect of information loss, a Context‐Aware Target Classification (CA‐TC) module coupled with a hybrid learning‐based predictive modeling technique for CVS systems is proposed. The CA‐TC consists of two modules: a Context‐Aware Map (CAM), and a Hybrid Gaussian Process (HGP) prediction system. Consequently, the vehicle safety applications use the information from the CA‐TC, making them more robust and reliable. The CAM leverages vehicles' path history, road geometry, tracking, and prediction; and the HGP is utilized to provide accurate vehicles' trajectory predictions to compensate for data loss (due to communication congestion) or sensor measurements' inaccuracies. Based on offline real‐world data, a finite bank of driver models that represent the joint dynamics of the vehicle and the drivers' behavior is learned. Offline training and online model updates are combined with on‐the‐fly forecasting to account for new possible driver behaviors. Finally, the framework is validated using simulation and realistic driving scenarios to confirm its potential in enhancing the robustness and reliability of CVS systems.
Mutual information‐based constant‐modulus waveform design for multiple‐input‐multiple‐output radar in spectrally crowded environment
Authors: Wang Xuyang , Tang Bo , Li Da , Wu Wenjun 
Published: January 2023

AbstractThis study considers designing constant‐modulus waveforms for multiple‐input‐multiple‐output radar in spectrally crowded environment. The mutual information is used as the waveform design metric. A constant‐modulus constraint is imposed on the waveforms to improve the hardware efficiency. To enhance the spectral compatibility of the transmit waveforms, a precise control on the interference energy produced on each reserved bandwidth is considered. To tackle the multi‐spectrally constrained waveform design problem, a minorisation‐maximisation based method is developed, and a quadratic function to minorise the objective function is derived. Then an alternating direction method of multipliers is used to tackle the quadratically constrained quadratic programming problem at each iteration. The effectiveness of the presented algorithm is demonstrated via simulation results.
Quasi-periodic oscillations in the γ-ray light curves of bright active galactic nuclei
Authors: Ren Helena X. , Cerruti Matteo , Sahakyan Narek 
Published: January 2023

Context. The detection of quasi-periodic oscillations (QPOs) in the light curves of active galactic nuclei (AGNs) can provide insights into the physics of the super-massive black holes (SMBHs) powering these systems and could represent a signature of the existence of SMBH binaries, setting fundamental constraints on SMBH evolution in the Universe.
Aims. The identification of long-term QPOs, characterized by periods on the order of several months to years, is particularly challenging and can only be achieved via all-sky monitoring instruments that provide unbiased, continuous light curves of astrophysical objects. The Fermi-LAT satellite, thanks to its monitoring observing strategy, is an ideal instrument for such a goal. Here, we aim to identify QPOs in the γ-ray light curves of the brightest AGNs within the Fermi-LAT catalog.
Methods. We analyzed the light curves of the 35 brightest Fermi-LAT AGNs, including data from the beginning of the Fermi mission (August 2008) to April 2021, with energies from 100 MeV to 300 GeV. Two time binnings were investigated: 7 and 30 days. The search for quasi-periodic features was then performed using the continuous wavelet transform. The significance of the result was tested via Monte Carlo simulations of artificial light curves with the same power spectral density and probability distribution function as the original light curves. The significances were then corrected for the look-elsewhere effect and provided as post-trials.
Results. We identified 24 quasars with candidate QPOs. Several of our candidates coincide with previous claims in the literature, namely: PKS 0537−441, S5 0716+714, Mrk 421, B2 1520+31, and PKS 2247−131. All our candidates are transient. The most significant multi-year QPO, with a period of about 1100 days, was observed in the quasar S5 1044+71. It is reported here for the first time.
The Gravitational Wave Universe Toolbox
Authors: Hendriks Kai , Yi Shu-Xu , Nelemans Gijs 
Published: January 2023

Context. In the current multi-messenger astronomy era, it is important that information about joint gravitational wave (GW) and electromagnetic (EM) observations through short gamma-ray bursts (sGRBs) remains easily accessible to each member of the GW-EM community. The possibility for non-experts to execute quick computations of joint GW-sGRB detections should be facilitated.
Aims. For this study, we constructed a model for sGRBs and added this to the framework of the previously built Gravitational Wave Universe Toolbox (GWToolbox or Toolbox). We provide expected joint GW-sGRB detection rates for different combinations of GW detectors and high-energy (HE) instruments.
Methods. We employed and adapted a generic GRB model to create a computationally low-cost top-hat jet model suitable for the GWToolbox. With the Toolbox, we simulated a population of binary neutron stars (BNSs) observed by a user-specified GW detector such as LIGO, Virgo, the Einstein Telescope (ET), or the Cosmic Explorer (CE). Based on the characteristics of each binary, our model predicts the properties of a resulting sGRB, as well as its detectability for HE detectors such as Fermi/GBM, Swift/BAT, or GECAM.
Results. We report predicted joint detection rates for combinations of GW detectors (LIGO and ET) with HE instruments (Fermi/GBM, Swift/BAT, and GECAM). Our findings stress the significance of the impact that ET will have on multi-messenger astronomy. While the LIGO sensitivity is currently the limiting factor regarding the number of joint detections, ET will observe BNSs at such a rate that the vast majority of detected sGRBs will have a GW counterpart observed by ET. These conclusions hold for CE as well. Additionally, since LIGO can only detect BNSs up to a redshift of ~0.1 where few sGRBs exist, a search for sub-threshold GW signals at higher redshifts using sGRB information from HE detectors has the potential to be very successful and significantly increase the number of joint detections. Equivalently, during the ET era, GW data can assist in finding sub-threshold sGRBs, potentially increasing, for example, the number of joint ET-Fermi/GBM observations by ~270%. Lastly, we find that our top-hat jet model underestimates the number of joint detections that include an off-axis sGRB. We corrected for this by introducing a second, wider and weaker jet component. We predict that the majority of joint detections during the LIGO/Virgo era will include an off-axis sGRB, making GRB170817A not as unlikely as one would think based on the simplest top-hat jet model. In the ET era, most joint detections will contain an on-axis sGRB.
A kinematically detected planet candidate in a transition disk
Authors: Stadler J. , Benisty M. , Izquierdo A. , Facchini S. , Teague R. , Kurtovic N. , Pinilla P. , Bae J. , Ansdell M. , Loomis R. , Mayama S. , Perez L. M. , Testi L. 
Published: January 2023

Context. Transition disks are protoplanetary disks with inner cavities possibly cleared by massive companions. Observing them at high resolution is ideal for mapping their velocity structure and probing companion–disk interactions.
Aims. We present Atacama Large Millimeter/submillimeter Array (ALMA) Band 6 dust and gas observations of the transition disk around RXJ1604.3–2130 A, known to feature nearly symmetric shadows in scattered light, and aim to search for non-Keplerian features.
Methods. We studied the 12CO line channel maps and moment maps of the line-of-sight velocity and peak intensity. We fitted a Keplerian model of the channel-by-channel emission to study line profile differences and produced deprojected radial profiles for all velocity components.
Results. The 12CO emission is detected out to R ∼ 1.8″ (265 au). It shows a cavity inward of 0.39″ (56 au) and within the dust continuum ring (at ∼0.56″, i.e., 81 au). Azimuthal brightness variations in the 12CO line and dust continuum are broadly aligned with the shadows detected in scattered-light observations. We find a strong localized non-Keplerian feature toward the west within the continuum ring (at R = 41 ± 10 au and PA = 280 ± 2°). It accounts for Δvϕ/vkep ∼ 0.4 or Δvz/vkep ∼ 0.04, depending on if the perturbation is in the rotational or vertical direction. A tightly wound spiral is also detected and extends over 300° in azimuth, possibly connected to the localized non-Keplerian feature. Finally, a bending of the iso-velocity contours within the gas cavity indicates a highly perturbed inner region, possibly related to the presence of a misaligned inner disk.
Conclusions. While broadly aligned with the scattered-light shadows, the localized non-Keplerian feature cannot be solely due to changes in temperature. Instead, we interpret the kinematical feature as tracing a massive companion located at the edge of the dust continuum ring. We speculate that the spiral is caused by buoyancy resonances driven by planet–disk interactions. However, this potential planet at ∼41 au cannot explain the gas-depleted cavity, the low accretion rate, and the misaligned inner disk, which suggests the presence of another companion closer in.
An attempt to apply laser combustion to palm waste
Authors: Awad Fatima M. , Alsabah Yousef A. , Marouf Ali A.S. , Orsod Mohammed U. 
Published: January 2023

The focus of this study was to develop a method to demonstrate the feasibility of obtaining useful and high-value resources from Phoenix dactylifera residues and, to determine the physical and chemical properties of the ash of dates-palm-tree remains. Date-palm leaves and fiber samples were combusted for 50 s, using an Nd: YAG laser with 40 W output power. It was found, that combustion of one gram of agricultural waste could be completed in 50 s and 40 W by laser while 10 g required 1.5–10 min and 300–800 W power by microwave and at least 2 h with 1500 W power for conventional heating for 10 g. The subjects of this treatment, the leaves and fiber samples, before and after combustion were investigated by X-Ray Diffraction (XRD) and Fourier Transform Infrared (FTIR). The XRD results of the palm-fiber after combustion reveal that the samples were crystallized with a rhombohedral phase of acetamide and hatrurite, orthorhombic finite, and Ca4Si2O6(CO3)(OH)2, and a monoclinic phase of ikaite properties. The XRD patterns of palm-leaf after combustion reveal that the samples were crystallized with orthorhombic hillebrandite, rhombohedral acetamide, and the monoclinic phase of each karpatite, morganite, and howlite. Finally, the FTIR exhibited several absorbance peaks, assigned to silica.
MiR-99a-5p Inhibits the Proliferation and Migration of Human Retinal
Microvascular Endothelial Cells by Targeting NOX4
Authors: Yu Haizhen , Zhang Xu , Wang Xuyang , Chen Wangling , Lao Wei , Chen Yunxin 
Published: January 2023

AbstractDiabetic retinopathy is one of the common microvascular complications of
diabetes, and it is the main cause of vision loss among working-age people. This
study interpreted the roles of miR-99a-5p in DR patients and human retinal
microvascular endothelial cell (hRMECs) injury induced by high glucose. The
expression of miR-99a-5p was detected in patients with NDR, NPDR, and PDR. The
indictive impacts of miR-99a-5p were tested by the ROC curve, and the link
between miR-99a-5p and clinical information was verified by the Pearson test. HG
was used to instruct cell models. The CCK-8 and transwell methods were performed
to detect the proliferative and migrated cells. The targeted relationship was
explained by luciferase activity. The content of miR-99a-5p was gradually
lessened in NPDR and PDR patients. MiR-99a-5p might differentiate DR patients
from NDR patients and PDR patients from NPDR patients. The interconnection
between miR-99a-5p and clinical factors was endorsed in all DR patients.
Overexpression of miR-99a-5p assuaged the abnormality of cell migration and
proliferation of hRMECs triggered by HG. NOX4 was a downstream signaling
component of miR-99a-5p. In conclusion, MiR-99a-5p protected hRMECs against HG
damage, and the miR-99a-5p might be a novel target for diagnosis of DR.
Sarcopenia – Definition, Radiological Diagnosis, Clinical Significance
Authors: Vogele Daniel , Otto Stephanie , Sollmann Nico , Haggenmüller Benedikt , Wolf Daniel , Beer Meinrad , Schmidt Stefan Andreas 
Published: January 2023

Background Sarcopenia is an age-related syndrome characterized by a loss of muscle mass and strength. As a result, the independence of the elderly is reduced and the hospitalization rate and mortality increase. The onset of sarcopenia often begins in middle age due to an unbalanced diet or malnutrition in association with a lack of physical activity. This effect is intensified by concomitant diseases such as obesity or metabolic diseases including diabetes mellitus.
Method With effective preventative diagnostic procedures and specific therapeutic treatment of sarcopenia, the negative effects on the individual can be reduced and the negative impact on health as well as socioeconomic effects can be prevented. Various diagnostic options are available for this purpose. In addition to basic clinical methods such as measuring muscle strength, sarcopenia can also be detected using imaging techniques like dual X-ray absorptiometry (DXA), computed tomography (CT), magnetic resonance imaging (MRI), and sonography. DXA, as a simple and cost-effective method, offers a low-dose option for assessing body composition. With cross-sectional imaging techniques such as CT and MRI, further diagnostic possibilities are available, including MR spectroscopy (MRS) for noninvasive molecular analysis of muscle tissue. CT can also be used in the context of examinations performed for other indications to acquire additional parameters of the skeletal muscles (opportunistic secondary use of CT data), such as abdominal muscle mass (total abdominal muscle area – TAMA) or the psoas as well as the pectoralis muscle index. The importance of sarcopenia is already well studied for patients with various tumor entities and also infections such as SARS-COV2.
Results and Conclusion Sarcopenia will become increasingly important, not least due to demographic changes in the population. In this review, the possibilities for the diagnosis of sarcopenia, the clinical significance, and therapeutic options are described. In particular, CT examinations, which are repeatedly performed on tumor patients, can be used for diagnostics. This opportunistic use can be supported by the use of artificial intelligence.
Key Points:

Citation Format
Operative Versorgung der Extremitäten und der
Wirbelsäule bei Achondroplasie
Authors: Roth Andreas , Schumann Eckehardt , Ghanem Mohamed , Heyde Christoph-Eckhard 
Published: January 2023

ZusammenfassungDie Achondroplasie gilt als häufigste Form des genetisch bedingten
Kleinwuchses. Zur Verbesserung des Wachstums erfolgen in Abhängigkeit
vom klinischen Befund und vom Alter operative Eingriffe an den
Extremitäten in Form von Korrektur- und Verlängerungsosteotomie.
Nur ausgeprägte Beindeformitäten sollten korrigiert werden. Die
regelmäßig auftretende flexible Kyphose wird in der Regel
konservativ behandelt. Eine operative Versorgung der Wirbelsäule erfolgt
bei spinaler Stenose. Die Ergebnisse der chirurgischen Therapie sind sehr gut.
Insbesondere bei Knochenverlängerungen muss jedoch über
häufig auftretende Komplikationen aufgeklärt werden. Neue
medikamentöse Behandlungsmethoden zur Wachstumsbeeinflussung befinden
sich in der Entwicklung.