bluuebunny/crossref_metadata_2025_split huggingface dataset:
Children's Oncology Group's 2023 blueprint for research: Cellular therapy and stem cell transplantation
Authors: Kitko Carrie L. , Bollard Catherine M. , Cairo Mitchell S. , Chewning Joseph , Fry Terry J. , Pulsipher Michael A. , Shenoy Shalini , Wall Donna A. , Levine John E. 
Published: July 2023

AbstractSince the publication of the last Cellular Therapy and Stem Cell Transplant blueprint in 2013, Children's Oncology Group cellular therapy‐based trials advanced the field and created new standards of care across a wide spectrum of pediatric cancer diagnoses. Key findings include that tandem autologous transplant improved survival for patients with neuroblastoma and atypical teratoid/rhabdoid brain tumors, one umbilical cord blood (UCB) donor was safer than two UCB donors, killer immunoglobulin receptor (KIR) mismatched donors did not improve survival for pediatric acute myeloid leukemia when in vivo T‐cell depletion is used, and the depth of remission as measured by next‐generation sequencing‐based minimal residual disease assessment pretransplant was the best predictor of relapse for acute lymphoblastic leukemia. Plans for the next decade include optimizing donor selection for transplants for acute leukemia/myelodysplastic syndrome, using novel engineered cellular therapies to target a wide array of malignancies, and developing better treatments for cellular therapy toxicities such as viral infections and graft‐vs‐host disease.
Development of chopped (non‐woven) carbon fiber reinforced composite sheet and its electrothermal performance for heating applications
Authors: Kaushal Shweta , K. Abhishek , Dhakate S. R. 
Published: July 2023

AbstractNon‐woven carbon fiber sheet‐based heaters have been used for various thermal and material science applications, which possess rapid thermal heating at low input power. This work investigates the optimization of chopped carbon fiber composite sheet for heating applications. Here, different lengths of chopped carbon fiber have been used to fabricate the composite sheet. The parameters of composite sheets, such as morphology, porosity, electrical conductivity, mechanical property, and thermal stability, were studied. Besides, the electrothermal performance of prepared sheet heaters was investigated, and the results were compared at the input voltages of 10 and 12 V. The input power consumed by different sheet heaters was also investigated. The optimal chopped size of the carbon fiber composite sheet showed the highest surface thermal heating temperature of 245°C at 12 V.
Emotional distress in cancer survivors from various ethnic backgrounds: Analysis of the multi‐ethnic HELIUS study
Authors: Müller Fabiola , Veen Linde M. , Galenkamp Henrike , Jim Heather S. L. , Lok Anja , Nieuwkerk Pythia T. , Suurmond Jeanine , van Laarhoven Hanneke W. M. , Knoop Hans 
Published: July 2023

AbstractPurposeInsight into emotional distress of cancer survivors from ethnic minority groups in Europe is scarce. We aimed to compare distress levels of survivors from ethnic minorities to that of the majority population, determine whether the association between having cancer (yes vs. no) and distress differs among ethnic groups and investigate sociocultural correlates of distress.MethodsCross‐sectional data were derived from HELIUS, a multi‐ethnic cohort study conducted in the Netherlands. Of 19,147 participants, 351 were diagnosed with cancer (n = 130 Dutch, n = 75 African Surinamese, n = 53 South‐Asian Surinamese, n = 43 Moroccan, n = 28 Turkish, n = 22 Ghanaian). Distress (PHQ‐9, MCS‐12) and correlates were assessed by self‐report. Cancer‐related variables were derived from the Netherlands Cancer Registry.ResultsSurvivors were on average 7 years post‐diagnosis. Survivors from South‐Asian Surinamese, Moroccan, Turkish and Ghanaian origin reported more distress than survivors from Dutch origin (effect sizerange: 0.44–1.17; adjusted models). The association between having cancer or not with distress differed in direction between Dutch and the non‐Dutch ethnic groups: Non‐Dutch cancer patients tended to have more distress than their cancer‐free peers, whereas Dutch cancer patients tended to have less distress than their cancer‐free peers. For Moroccan and Turkish patients, the acculturation style of separation/marginalization, compared to integration/assimilation, was associated with higher depressive symptoms. In analyses pooling data from all ethnic minorities, lower health literacy, lower emotional support satisfaction and younger age at the time of migration were associated with higher depressive symptoms. Lower health literacy, fewer emotional support transactions, and more frequent attendance at religious services were associated with worse mental health.ConclusionCancer survivors from ethnic minorities experience more distress than those from the majority population. Culturally sensitive supportive care should be considered.
Fine‐scale environment control on ground surface temperature and thaw depth in a High Arctic tundra landscape
Authors: Khani Hadi Mohammadzadeh , Kinnard Christophe , Gascoin Simon , Lévesque Esther 
Published: July 2023

AbstractSurface conditions are known to mediate the impacts of climate warming on permafrost. This calls for a better understanding of the environmental conditions that control the thermal regime and the depth of the active layer, especially within heterogeneous tundra landscapes. This study analyzed the spatial relationships between thaw depths, ground surface temperature (GST), and environmental conditions in a High Arctic tundra environment at Bylot Island, Nunavut, Canada. Measurements were distributed within the two dominant landforms, namely earth hummocks and low‐center polygons, and across a topographic gradient. Our results revealed that GST and thaw depth were highly heterogeneous, varying by up to 3.7°C and by more than 20 cm over short distances (<1 m) within periglacial landforms. This microscale variability sometimes surpassed the variability at the hillslope scale, especially in summer. Late‐winter snowpack thickness was found to be the prime control on the spatial variability in winter soil temperatures due to the highly heterogeneous snow cover induced by blowing snow, and this thermal effect carried over into summer. However, microtopography was the predominant driver of the spatial variability in summer GST, followed by altitude and moss thickness. In contrast, the spatial variability in thaw depth was influenced predominantly by variations in moss thickness. Hence, summer microclimate conditions dominated active layer development, but a thicker snowpack favored soil cooling in the following summer, due to the later disappearance of snow cover. These results enhance our understanding of High Arctic tundra environments and highlight the complexity of considering surface feedback effects in future projections of permafrost states within heterogeneous tundra landscapes.
Identifying sustainability assessment parameters for genetically engineered agrifoods
Authors: Wei Wei , Grieger Khara , Cummings Christopher L. , Loschin Nick , Kuzma Jennifer 
Published: July 2023

Societal Impact StatementA diverse portfolio of genetically engineered food crops, as well as animal livestock and fish, are currently being developed and commercialized. To ensure their contributions to long‐term sustainability, a broad range of environmental, health, ethical, and societal parameters should be used in their evaluations. This paper proposes a set of parameters to evaluate the sustainability of genetically engineered food and agriculture products and discusses mechanisms to improve their governance and oversight. With such holistic evaluations, genetic engineering applications that are deemed beneficial to sustainable agriculture could be identified in an effort to foster sustainability.SummaryTo achieve international sustainable development goals, food and agricultural production need to rely on sustainable and resilient practices. Traditional breeding as well as the use of new agricultural technologies, including genetic engineering and gene editing, have the potential to help achieve sustainable agrifood production. Although numerous oversight mechanisms exist to guarantee the secure and sustainable advancement and utilization of genetically engineered agrifoods, the majority of these mechanisms heavily depend on a narrow set of parameters to assess risks and safety concerning human health and nontarget organisms. However, a more comprehensive range of parameters should be considered to promote environmental and social sustainability in a more holistic manner. This Opinion article argues that to achieve a more sustainable agrifood production that relies on genetic engineering, governance systems related to new agrifood biotechnologies should incorporate a broader array of environmental, health, ethical, and societal factors to ensure their sustainability in the long‐term. To facilitate this process, we propose a set of parameters to help evaluate the sustainability of agrifoods that rely on genetic engineering. We then discuss major challenges and opportunities for formalizing sustainability parameters in US governance policy and decision‐making systems. Overall, this work contributes to further developing a more comprehensive assessment framework that aims to minimize potential risks and maximize potential benefits of agrifood biotechnology while also fostering sustainability.
VoroIF‐GNN: Voronoi tessellation‐derived protein–protein interface assessment using a graph neural network
Authors: Olechnovič Kliment , Venclovas Česlovas 
Published: July 2023

AbstractWe present VoroIF‐GNN (Voronoi InterFace Graph Neural Network), a novel method for assessing inter‐subunit interfaces in a structural model of a protein–protein complex, relying solely on the input structure without any additional information. Given a multimeric protein structural model, we derive interface contacts from the Voronoi tessellation of atomic balls, construct a graph of those contacts, and predict the accuracy of every contact using an attention‐based GNN. The contact‐level predictions are then summarized to produce whole interface‐level scores. VoroIF‐GNN was blindly tested for its ability to estimate the accuracy of protein complexes during CASP15 and showed strong performance in selecting the best multimeric model out of many. The method implementation is freely available at https://kliment-olechnovic.github.io/voronota/expansion_js/.
Functional analysis of neutral lipases in bug feeding and reproduction
Authors: Lu Hai‐Bin , Lu Jia‐Bao , Li Li‐Li , Zhang Ze‐Long , Chen Jian‐Ping , Li Jun‐Min , Zhang Chuan‐Xi , Huang Hai‐Jian 
Published: July 2023

AbstractBACKGROUNDThe bean bug, Riptortus pedestris, is known to cause significant economic losses in soybean crops due to its seed‐sucking behavior, but the mechanism of its adaptation to lipid‐rich seeds remains poorly understood. To exploit potential target genes for controlling this pest, neutral lipases are functionally characterized in this study.RESULTSIn this study, a total of 69 lipases were identified in R. pedestris, including 35 neutral lipases that underwent significant expansion. The phylogeny, expression patterns, and catalytic capacity of neutral lipases were investigated and we selected six salivary gland‐specific, eight gut‐specific, and three ovary‐specific genes for functional analysis. All three ovary‐specific neutral lipases (Chr1.3195, Chr1.0994, and Chr5.0087) are critical for insect reproduction, while a few gut‐specific neutral lipases (Chr4.0221 and Chr1.3207) influence insect survivorship or weight gain. In contrast, no significant phenotype change is observed when silencing salivary gland‐specific neutral lipases.CONCLUSIONThe lipases Chr1.3195, Chr1.0994, Chr5.0087, Chr4.0221, and Chr1.3207 are essential for R. pedestris feeding and reproduction, and the insect is highly sensitive to their deficiency, suggesting that neutral lipases are promising candidates for application in RNAi‐based control of this destructive pest. © 2023 Society of Chemical Industry.
Towards stunting eradication in Indonesia: Time to invest in community health workers
Authors: Miranda Adriana Viola , Sirmareza Trio , Nugraha Ryan Rachmad , Rastuti Maritta , Syahidi Habibi , Asmara Rindang , Petersen Zack 
Published: July 2023

AbstractIn Indonesia, home to the fourth‐largest children‐under‐five population globally, the stunting prevalence is among the highest in Asia. The detrimental and irreversible impacts of stunting warranted the government to aim for stunting eradication by 2030, with community health workers (CHWs) at the forefront of the program. With over 1.5 million Indonesian CHWs conducting monthly growth monitoring and counseling, the critical importance and cost‐effectiveness of CHWs in stunting management are clear. However, several implementation challenges continue to hinder their maximum potential. This includes unclear recruitment processes, the nonprofessional status of CHWs, unclear incentive schemes, research and funding constraints, and unclear role of stakeholders. This commentary examines the current involvement of CHWs in the Indonesian stunting program, the remaining issues, and recommendations to mitigate the identified challenges. Improvements in the recruitment process, recognition, and incentivization system, as well as cross‐sectoral collaboration, particularly in evidence creation and policy‐research continuum, are crucial in improving the current program and achieve the goal of stunting eradication.
Nonlinear Interaction between Two Chirped Broadband Single Photons
Authors: Li Yuanhua , Huang Yiwen , Qi Zhantong , Chen Xianfeng 
Published: July 2023

AbstractCoherent correlation between two distant broadband single photons can be realized by using the nonlinear optical method, which provides a key technology for spread‐spectrum communication in the quantum network. Here, sum‐frequency generation (SFG) between two broadband single photons is experimentally demonstrated by using chirp technology. The results show that the efficiency of the SFG is 6.51 × 10−8, and the visibility of coherent correlation of two distant broadband photons of the telecommunications band is 93.7%. This technique can also be used for other quantum applications, such as quantum entanglement swapping and quantum communication.
Fixed‐time disturbance observer based distributed cooperative containment control with fixed‐time anti‐saturation compensator for multi‐unmanned aerial vehicles
Authors: Cui Lei , Zhou Qi , Huang Di 
Published: July 2023

AbstractThis article proposes a fixed‐time backstepping distributed cooperative containment control scheme for multiple unmanned aerial vehicles (UAVs). A fixed‐time compensator is designed for the fixed‐wing UAVs actuator saturation problem. Based on this, an improved fixed‐time disturbance observer is proposed for the problem of the excessive initial peak. The problem of “complexity explosion” is solved by the fixed‐time differential filter. For the distributed containment control of multiple UAVs, a cooperative control architecture based on a fixed‐time anti‐saturation compensation system is proposed. The proposed algorithm can be shown practicable by using Lyapunov stability theory and graph theory. Simulation results are given to demonstrate the effectiveness of the proposed control scheme.
Traditional kriging versus modern Gaussian processes for large‐scale mining data
Authors: Christianson Ryan B. , Pollyea Ryan M. , Gramacy Robert B. 
Published: July 2023

AbstractThe canonical technique for nonlinear modeling of spatial/point‐referenced data is known as kriging in geostatistics, and as Gaussian Process (GP) regression for surrogate modeling and statistical learning. This article reviews many similarities shared between kriging and GPs, but also highlights some important differences. One is that GPs impose a process that can be used to automate kernel/variogram inference, thus removing the human from the loop. The GP framework also suggests a probabilistically valid means of scaling to handle a large corpus of training data, that is, an alternative to ordinary kriging. Finally, recent GP implementations are tailored to make the most of modern computing architectures, such as multi‐core workstations and multi‐node supercomputers. We argue that such distinctions are important even in classically geostatistical settings. To back that up, we present out‐of‐sample validation exercises using two, real, large‐scale borehole data sets acquired in the mining of gold and other minerals. We compare classic kriging with several variations of modern GPs and conclude that the latter is more economical (fewer human and compute resources), more accurate and offers better uncertainty quantification. We go on to show how the fully generative modeling apparatus provided by GPs can gracefully accommodate left‐censoring of small measurements, as commonly occurs in mining data and other borehole assays.
Integrating risk assessment for increased social resilience: Lessons from South Africa
Authors: Kruger Leandri , Sandham Luke A. , van Niekerk Dewald 
Published: July 2023

AbstractAmidst the increased exposure of vulnerable communities to disaster risks in recent years, the optimal use of Social Impact Assessment (SIA) for effective risk reduction, enhanced social resilience, and a more sustainable human environment is essential. The limited flexibility of SIA methodological guidance is a potential obstacle to optimal practice, particularly in developing countries with complex social contexts, such as South Africa. In this article, the potential integration of SIA with aspects of Disaster Risk Assessment (DRA) for improved practice is explored by evaluating commonalities and differences in South African SIA and DRA methodological guidelines in comparison with international good practice guidelines. While South African SIA guidance is in line with international good practice, definite shortcomings were observed, such as the absence of risk assessment guidance. The findings suggest that the incorporation of DRA has the potential to strengthen risk assessment in SIA practice through an integrated approach to social risk baseline studies. SIA and DRA practice communities will benefit from this integrated approach, and thereby contribute to improved social resilience, all of which should contribute to sustainable development outcomes, especially in hazard influenced contexts.
Beyond the direct effect of economic growth on child mortality in Sub‐Saharan Africa: does environmental degradation matter?
Authors: Fotio Hervé Kaffo , Gouenet René Marcel , Ngo Tedga Pauline 
Published: July 2023

AbstractUsing a sample of 45 Sub‐Saharan African countries over the 2000–2019 period, this paper contributes to the ongoing debate on the health effect of economic growth. Specifically, it investigates the direct effect of economic growth on child mortality as well as the indirect effect through environmental degradation. Findings from panel‐corrected standard errors, feasible generalized least squares, and Driscoll and Kraay standard errors show that economic growth has significantly decreased infant and under‐five mortality rates in Sub‐Saharan Africa. However, results from the mediation analysis reveal that, beyond its direct effect, economic growth has an indirect effect on under‐five mortality through greenhouse gas emissions. Implementing green growth policies should help minimize the indirect negative effect of economic growth on child mortality in Sub‐Saharan African countries.
In situ Synthesis of S‐scheme Polymer Heterojunction Poly(phenyl‐1,3,5‐yl)‐benzene)/g‐C3N4 Composites for Efficient Removal of Rhodamine B
Authors: Mao Na , Zhang Yu‐hang , Li Junyan , Gao Ying 
Published: July 2023

AbstractPoly(phenyl‐1,3,5‐yl)‐benzene/g‐C3N4 (PPB/g‐C3N4) catalysts were prepared by in situ for the removal of Rhodamine B from polluted water under visible light irradiation. In addition, the catalytic behavior of PPB/g‐C3N4 composites has been studied by using XRD, TEM, UV‐vis DRS and PL. The results show that PPB has been successfully loaded on g‐C3N4, PPB/g‐C3N4‐0.4 composite have good photo‐Fenton‐like catalytic performance. In the case of PPB/g‐C3N4+H2O2 composite, the RhB photo‐ removal efficiency was ∼96 % in 50 min. The removal rate of PPB/g‐C3N4+H2O2 composite is 9.4 times higher than that of pure g‐C3N4. Owing to the higher surface area and polymer heterojunction (PHJ), PPB/g‐C3N4‐0.4 composite have the superior photo‐Fenton‐like catalytic activity. Moreover, PPB/g‐C3N4 composite rendered excellent stability. Therefore, S‐scheme polymer heterojunction PPB/g‐C3N4 composite was synthesised without metal in situ, which are potential photo‐Fenton‐like catalyst for wastewater treatment under visible‐light irradiation, in which provided a new integration strategy.
Formation of the Short‐Range Order in Liquid Al−Ni−Sn Alloys
Authors: Yakovenko Olexiy , Kazimirov Volodymyr , Kashirina Yaroslavna , Sokolskii Volodymyr , Golovataya Nataliya , Kotova Natalia , Roik Oleksandr 
Published: July 2023

AbstractShort‐range order (SRO) in the liquid Al−Ni−Sn alloys has been investigated using the X‐ray diffraction method and Reverse Monte Carlo simulations. Obtained results point out a micro‐inhomogeneous structure of Al−Sn−Ni melts with Sn content between 10 and 65 at.% due to the presence of atomic clusters with the structure of liquid Sn and atomic clusters with Ni−Sn coordination. The influence of the atomic size ratio (size factor) and pair atomic interactions (energy factor) on the short‐range order of the investigated ternary melts are discussed. There is a competition between Al and Sn atoms in the formation of the SRO around Ni atoms due to the difference in bond energy in Ni−Al and Ni−Sn pairs. This competition, as well as a bigger radius of Sn atoms, results in the formation of atomic clusters with liquid Sn‐like local atomic structure.
Fabrication of Ternary Ag/g‐C3N4/BiVO4 Composites with Enhanced Visible‐Light‐Driven Photocatalytic Activity toward Rhodamine B Elimination
Authors: Hoang Lan‐Anh T. , Le‐Duy Nhat , Nguyen Trinh Duy , Lee Taeyoon 
Published: July 2023

AbstractBiVO4 and g‐C3N4 have gain attention for their potential in sustainable energy and environmental applications due to their visible light absorption properties. However, their limitations in terms of visible light absorption and electron‐hole separation have prompted efforts to enhance their energy utilization and reduce electron‐hole recombination. In our study, we investigated the fabrication of a ternary Ag/g‐C3N4/BiVO4 composite for Rhodamine B (RhB) degradation under visible light irradiation using a combination of photo‐deposition and calcination methods. Our findings demonstrate that the Ag/g‐C3N4/BiVO4 outperforms g‐C3N4, BiVO4, and g‐C3N4/BiVO4 in terms of RhB degradation rate. This improvement can be attributed to the improved light absorption and synergetic effects on charge transfer and photoelectron‐hole recombination resulting from the incorporation of Ag into the ternary system. This ternary Ag/g‐C3N4/BiVO4 composite has potential as a photocatalyst for the removal of organic pollutants due to its reasonable design and superior effectiveness.