bluuebunny/crossref_metadata_2025_split huggingface dataset:
INFERTILITY SCREENING
Authors: Amran Rizani , Effendi Kms Yusuf , Zulqarnain Iskandar , Manan Heriyadi , Usman Fatimah , Hakim M Komarul , Patricia Vicela , Rizany Selly , Rama Anton , Fachroni Achmad 
Published: May 2023

Infertility is a common condition caused by the female factor, male factor, or both. Infertility problems can have a significant impact on married couples who experience them. In addition to causing medical problems, infertility can also cause economic and psychological problems. Couples who experience infertility will undergo a long process of evaluation and treatment, where this process can be both physical and psychological for the infertile couple. The aim of this article is presenting a literature study on infertility screening. Infertility affects millions of people of reproductive age worldwide and impacts family and community life. Estimates suggest that between 48 million couples and 186 million people are living with infertility. Infertility occurs in 15% of couples. Female factors cause infertility in 50-70%, and malefactors are the cause of infertility in 40-50% of couples. Given the high prevalence of malefactors in infertility heterosexual couples, medical history and early evaluation of male partners are needed. Ovulation dysfunction was defined as a history of oligomenorrhea or amenorrhea, recurrent luteal progesterone levels of less than 3 ng/mL, or both. For many women, a menstrual history is sufficient to assess ovulatory function. The clinical history can be used to assess the ovulatory cycle as most women will have regular menstrual cycles every 25–35 days. Anovulation may be associated with obesity, hypothalamic and pituitary dysfunction, PCOS, and other etiologies. Polycystic ovary syndrome is the most common cause of ovulatory infertility.
Women with PCOS who have been diagnosed are at increased risk of the metabolic syndrome associated with cardiovascular events and negatively impacting pregnancy.
Infertility is the failure of a couple to get pregnant for at least 12 months having regular sex without contraception, or also known as primary infertility. Secondary infertility is the inability of a person to have children or maintain a pregnancy. Idiopathic infertility refers to infertile couples who have undergone standard examinations, including ovulation tests, tubal patency, and semen analysis with normal results.
PREVENTION OF LOW BACK PAIN COMPLAINTS TO STUDENTS DURING ONLINE LEARNING IN THE TIME OF THE COVID-19 PANDEMIC
Authors: Septadina Indri Seta , Wardiansyah Wardiansyah , Adnindya Msy Rulan , Suciati Tri 
Published: May 2023

Low back pain is a widespread health problem worldwide and the leading cause of disability. Low back pain or lower back pain is a Musculoskeletal disorder caused by strenuous physical activity, and It causes muscle spasms and back stiffness. This complaint occurs because the muscles receive pressure due to workload continuously without getting
relaxation opportunities. The incidence of low back pain in the world each year varies wildly, reaching 15 - 45%. According to WHO (2013), shows that 33% of the population in persistent pain develops. Data for LBP sufferers in Indonesia is unknown but is estimated to vary between 7.6% to 37% of the total population. LBP is not caused by organic disorders but by the wrong body position at work. With the issuance of a work from home policy for workers and online at students and students, there is a shift in low back pain at a young age. Low back pain continues to increase 5% every year. The intensity of physical movement, work and study so that laptops and smartphones are increasing. The increase in the duration of media use causes various kinds of effects, including influencing how students and workers learn.
PRODUCTION OF YELLOW WOOD ROOT TEA AS A BLOOD SUGAR STABILIZER
Authors: Fatmawati Fatmawati , Athiah M , Sinulingga S , Oswari L.O , Safyudin Safyudin 
Published: May 2023

Diabetes mellitus is a disease or metabolic disorder that is increasing year by year, characterized by high blood sugar levels as a result of insulin function insufficiency. Diabetes mellitus, which is often referred to as diabetes, is a disease or metabolic disorder that is increasing year by year, characterized by high blood sugar levels as a result of insulin function insufficiency. Treatment is by using drugs. Currently, a treatment using herbal medicine is being developed, one of which is Kayu kuning, where in previous studies it was found that the roots of Kayu kuning can reduce blood glucose levels. This has triggered the Biochemistry and Medical Chemistry section of the Faculty of Medicine to introduce to the public the preparations of this herbal medicine with ready-to-use packaging and the right dosage. The process of making tea is carried out at the Chemical Basic Medicine Laboratory, Faculty of Medicine, Sriwijaya University. About 5.6 kg of yellow wood root, washed and cut into small pieces then dried and ground to obtain a coarse powder (simplicia) of about 2.5 kg. Yellow wood root simplicia is put into tea bags weighing 10 g per bag. One tea bag can be brewed with 200 mL of hot water and drunk once a day. In this service, 250 tea bags were produced which were packaged in 50 packages (5 tea bags/package). The production of this yellow wood root tea has been carried out in the Komplek Azhar Lama, Kenten Laut, Palembang.
Keywords: Herbal medicine, yellow root (Arcangelisia flava)
PREVENTION OF ENDOMETRIAL CANCER
Authors: Saleh Agustria Z 
Published: May 2023

Endometrial carcinoma is a malignancy originating from the epithelial cells lining the uterine cavity. 1,3 Currently, endometrial carcinoma is often found in gynecological malignancies. Endometrial carcinoma is the sixth leading cause of death from malignancy in women. In Indonesia, endometrial cancer ranks third for genital cancer after cervical (cervical) and ovarian cancer. An endometrial biopsy is done to diagnose and evaluate abnormal intrauterine bleeding, t. However, in patients who cannot undergo an endometrial biopsy because of cervical stenosis or symptoms persist despite normal biopsy results, dilatation and curettage may be performed under anesthesia. Dilatation and curettage procedures are currently the gold standard for the diagnosis of endometrial cancer.2 Microscopic examination of endometrial biopsy and endocervical curettage can usually confirm the diagnosis of endometrioid or mucinous adenocarcinoma but rarely can be associated with the initial lesion of cervical adenocarcinoma in situ or atypical hyperplasia of the endometrium. The prognosis of patients with this type is poor and has a lower survival rate than patients with type 1. In addition, in some types of type 2 endometrial adenocarcinoma found an increase in molecules that are generally found in type 1, this indicates that type 2 endometrial adenocarcinoma can occur as a worsening. from the pre-existing type 1. 4 The risk of endometrial cancer is strongly associated with family history, Therefore, screening is needed as early as possible.6
PREVENTION OF CERVICAL CANCER
Authors: Agustiansyah Patiyus 
Published: May 2023

Cervical cancer is the fourth most common cancer in women globally. In 2018, 570.000 women were diagnosed with cervical cancer, and 311.000 of them died from the disease.1 In Indonesia, cervical cancer is the second most common cancer. According to GLOBOCAN, there was a decrease in incidence from 17.2% to 9.2% from 2018 to 2020. This decrease has also been seen in other countries such as the United States. However, the distribution of cervical cancer varies widely among countries. WHO projected that the global burden of cervical cancer is projected to continue to increase, rising to 700 000 cases (21% increase) and 400 000 deaths (27% increase) in 2030 compared to 2018. Preventive measures become an important step to manage this situation. Preventions such as HPV vaccination, screening, and treatment of precancerous lesions have been found to be effective.
NEUROPATI PERIFER SEBAGAI KOMPLIKASI NEUROLOGI PASCA INFEKSI COVID-19
Authors: Christin Theresia 
Published: May 2023

Severe acute respiratory syndrome (SARS-CoV-2) disebabkan virus COVID-19 telah menjadi pandemic yang mengancam jiwa dan mempengaruhi organ sistem saraf pusat dan perifer. Neuropati perifer adalah proses patologi mengenai susunan saraf perifer, meliputi kelemahan motorik, gangguan sensorik, otonom, dan melemahnya refleks tenon yang dapat bersifat akut atau kronik, berupa proses demielinisasi atau degenerasi aksonal atau keduanya. Sebanyak 400 Pasien COVID-19 dengan atau tanpa gejala neuromuscular dilakukan pemeriksaan elektrofisiologi prevalensi mencapai 56,3% dari semua pasien COVID 19. Gejala umum yang dilaporkan pada pasien dengan post–acute COVID-19 syndrome (PACS) adalah tanda - tanda keterlibatan sistem saraf perifer baik gejala sensorik (parestesia dan nyeri neuropatik) maupun gejala disautonomik serta sistem otot, seperti mialgia dan kelemahan. Mengingat manifestasi klinis neuropati perifer sangat bervariasi yang disebabkan oleh COVID 19 diperlukan evaluasi sistematis dan menyeluruh meliputi klinis, laboratorium penunjang dan tes elektrodiagnostik, agar dapat direncanakan terapi dengan baik.
PENGENDALIAN MIOPIA PADA ANAK
Authors: Ismail Ani 
Published: May 2023

Miopia adalah kelainan refraksi yang paling sering ditemukan dan merupakan salah satu penyebab utama gangguan penglihatan. Prevalensi miopia pada anak-anak meningkat di seluruh dunia dan paling tinggi ditemukan pada anak-anak keturunan Asia Timur. Di Cina, sebanyak 90% remaja dan dewasa muda mengalami miopia, sedangkan di Seoul, terdapat 96,5% remaja dan dewasa muda mengalami miopia. Miopia derajat tinggi telah dikaitkan dengan berbagai komplikasi, seperti ablatio retina, degenerasi makula, neovaskularisasi koroid, katarak, dan glaukoma. Risiko tersebut meningkat seiring dengan meningkatnya kecepatan progresivitas miopia dan pemanjangan aksial bola mata. Prevalensi yang semakin meningkat, morbiditas yang mungkin terjadi, serta beban biaya yang ditimbulkan, menyebabkan miopia telah menjadi masalah kesehatan masyarakat, sehingga perlu dilakukan penatalaksaan yang cepat dan tepat terhadap kejadian miopia ini. Ada berbagai macam metode untuk mencegah progresivitas miopia yaitu dengan ortokeratologi (Ortho-K), instrumentasi (spectacle, contact lens), modifikasi lingkungan seperti meningkatkan aktivitas luar rumah dan paparan sinar matahari, atropin dosis rendah, dan terapi red-light tingkat rendah dikaitkan dengan upaya pencegahan progresivitas miopia ini. Atropin dosis rendah merupakan intervensi paling efektif untuk memperlambat perkembangan miopia, namun masih diperlukan studi lebih lanjut dengan sampel yang lebih besar dan follow-up jangka panjang terkait progresivitas miopia.
PERAN HERBAL DALAM FARMAKOLOGI TERAPI
Authors: Kamaluddin Muhammad Totong 
Published: May 2023

Herbal adalah tumbuhan yang mengandung berbagai zat kimia aktif sebagai metabolit sekunder, dapat berinteraksi dengan sistem biologi dari mahluk hidup hingga menimbulkan efek yang dapat diamati, terukur dan prediktif sehingga herbal perlu diteliti guna menaksir respon biologiknya. Berbagai zat kimia yang diekstrak dari tumbuhan/herbal dapat dikenali, diklasifikasi sesuai kandungan biokimiawi sehingga efeknya dapat dibandingkan dengan zat kimia standar. Ekstrak yang diperoleh disiapkan serta diolah lebih lanjut dengan teknologi farmasi untuk menjadi obat baru guna dievaluasi efek farmakoterapinya baik berperan untuk pengobatan, kondisi patologis atau justru meningkatkan peran/fungsiya saja. Interaksi zat kimia dari herbal tersebut akan menimbulkan respon biologi (efek terapetik) sesuai dengan hukum dan aturan farmakologi. Respon farmakologik ini dievaluasi dengan obat standar baik pada binatang ataupun manusia. Temuan dalam kajian farmakokinetik dan farmakodinamik tersebut tidak akan menimbulkan respon baru pada sel dan jaringan yang diuji, kecuali berperan untuk menentukan perjalanan patologi suatu penyakit.
ANNOYING ACNE: WHAT SHOULD WE DO?
Authors: Kurniawati Yuli , Octyvani Tiar Marina 
Published: May 2023

Akne vulgaris (AV) adalah peradangan kronis pada unit pilosebasea, yang melibatkan 4 elemen kunci dalam patogenesis, termasuk hiperproliferasi folikel epidermis, produksi sebum, aktivitas Cutibacterium acnes, serta respon imun inflamasi. Akne vulgaris terjadi pada 85% populasi dunia dan menimbulkan berbagai dampak negatif pada pasien. Penatalaksanaan AV tetap menjadi tantangan bagi sebagian besar klinisi, karena terdapat beberapa faktor internal dan eksternal yang menyebabkan AV rekalsitran namun cenderung diabaikan. Tinjauan pustaka ini bertujuan untuk memaparkan berbagai faktor yang menyebabkan AV rekalsitran sehingga klinisi dapat mengidentifikasi tantangan ini dan menanganinya dengan tepat. Beberapa strategi untuk menangani AV rekalsitran juga diuraikan.
Formulation and Evaluation of Novel Aceclofenac Matrix Tablet Using Natural Polymers
Authors: Kumar Rajesh , Sharma Dr. Vijay , Kumawat Sunil 
Published: May 2023

The current study attempted to design and create Aceclofenac sustained release matrix tablets employing different proportions of Hibiscus rosa-sinensis mucilage, Mimosa Pudica mucilage as natural polymers and povidone.Aceclofenac is widely used as a centrally acting muscle relaxant; therefore, have been selected to prepare sustained release dosage forms.Different types of evaluation parameters were evaluated like appearance, thickness, diameter, weight variation, hardness, friability, drug content, in-vitro dissolution studiesand stability studies.Sustained release matrix tablets can improve patient compliance by lowering the total dose and dosing schedule, which can be extremely beneficial in the treatment of chronic illnesses.
Key words:S, , .
Measurements of Breakdown and Buildup of Thixotropy in Cement Pastes Containing Diatomaceous Earth
Authors: Hasanzadeh Bashir , Sun Zhihui 
Published: May 2023

This paper proposes a comprehensive series of protocols that can make quantitative measurements on both breakdown and buildup aspects of thixotropic behaviors of cement pastes. While measuring breakdown and buildup separately, the correlations between these two aspects have also been investigated. Cement pastes with different water-to-binder ratios (w/b=0.4, 0.5 and 0.6) and different replacement levels of Diatomaceous Earth (DE) (0%, 2%, 6% and 10% by weight of cement) were studied. To simulate the real on-site conditions, parameters such as pressure and temperature were also considered during the measurement. The research found that increase in DE replacement dosage can reduce the energy required to breakdown thixotropic structure of cement pastes while no specific trend on buildup aspect was observed. Among the three used w/b ratios, the 0.5 w/b ratio has the most reduction effect in breakdown energy, where using 10% DE can lead to 65% of energy reduction in breakdown compared to the control sample. However, the measured yield stress for these specimens were very similar to each other. In addition, increase in temperature significantly increases the buildup ratio of cement pastes while increase in pressure as high as 20 MPa has a minimal impact on thixotropic properties of cement pastes.
The analysis of decomposition rate of Vermigot fertilizer (vermicompost and kasgot) by utilizing of Black Soldier Fly larvae and earthworms with and without technique feeding
Authors: Sebayang Nur Ulina Warnisyah , Sabrina Tengku , Rahmawati Nini , Lubis Nursiani 
Published: May 2023

ABSTRACT

One of the efforts in managing waste is to carry out environmentally friendly bioconversion with one of the most popular composting is vermicomposting. The use of insects in composting is also one of the new technologies, namely the Black Soldier Fly larvae. The combination of two types of decomposing organisms that are synergistic can increase the effectiveness of the decomposition process. The purpose of this study was to analyze the rate of decomposition of vermigot fertilizer in the treatment of cow manure and banana stem waste by utilizing a combination of BSF larvae and earthworms. This study used a non-factorial randomized block design method with 2 techniques (feeding and without feeding), namely D0 = without decomposers; D1 = earthworm (100%); D2 = BSF larvae (100%); D3 = earthworms: BSF larvae (50% : 50% kg); D4 = earthworms : BSF larvae (25% : 75%); D4 = earthworms: BSF larvae (75% : 25%). The results of this study showed that the pH of the vermigot ranged from neutral to slightly alkaline (6.4 - 7.8) in the non-feeding technique, while the pH of the vermigot in the feeding technique was slightly acidic (5.7 - 5.8). The temperature of the vermigot in the non-feeding and feeding technique is the same, ranging from (26 - 31oC) but in the non-feeding technique the temperature tends to rise until the 5th day and tends to decrease on the 7th day to the 21st day. Meanwhile, the temperature of the vermigot with the feeding technique tends to experience fluctuations.
Relationship between Allergic Rhinitis to Quality of Life of Students of Faculty of Medicine Universitas Sumatera Utara Batch 2018
Authors: Delinda Anna , Andrina Rambe  
Published: May 2023

Background:
Allergic rhinitis is an inflammation mediated by Immunoglobulin E (IgE) with symptoms such as runny nose, sneezing, nasal congestion, with or without itchy nose. Although allergic rhinitis is not a dangerous disease, this disease has an impact on decreasing the quality of life of the sufferer which can interfere with daily activities. Objective: This study use to determine the relationship between allergic rhinitis and quality of life among students of the Faculty of Medicine, Universitas Sumatera Utara, batch 2018. Methods: This study used an observational analytical method with a cross-sectional study approach. The research sample was determined by simple random sampling technique and used two questionnaires, namely SFAR to assess allergic rhinitis and SF 36 to assess quality of life. Results: Based on the study, the number of allergic rhinitis sufferers from 72 students of the Faculty of Medicine, Universitas Sumatera Utara, batch 2018, 38 students suffering from allergic rhinitis. The results of data analysis using the Chi Square statistical test showed that there was a significant relationship between allergic rhinitis and quality of life, p (p value) of 0.001 (p <0.05). Conclusion: There is a relationship between allergic rhinitis and quality of life in 2018 students of the Faculty of Medicine, Universitas Sumatera Utara.
Analysis of Risk Factors Associated with Maskne in the Era of the COVID-19 Pandemic
Authors: S. Az-Zahra  , N. K. Jusuf  
Published: May 2023

The necessity to always use a mask in the era of the COVID-19 pandemic has given rise to a new term called maskne. Maskne is the appearance of acne that is triggered by wearing a mask. It usually occurs specifically in the area covered by the mask, focused on the cheeks, chin, and nose. This study aims to determine the risk factors associated with the occurrence of maskne. A cross-sectional study was conducted on the Faculty of Medicine students, Universitas Sumatera Utara class 2018. This study uses primary data from questionnaires and observation of respondents' face photos. Based on statistical analysis, 99 out of 221 respondents (44.8%) experienced maskne. Bivariate analysis shows p-values <0.05 for gender, duration of mask use, and previous acne history. On the other hand, it was obtained p-value >0.05 for the type of mask and mask changing habit. Based on multivariate analysis, the p-value <0.05 for gender indicates that gender is the most dominant risk factor in the incidence of maskne. Furthermore, there is a significant association between gender and the occurrence of maskne. Females are twice as likely to experience maskne.
THE POTENTIAL OF Azadirachta indica (NEEM TREE) LEAVES FOR BIOETHANOL PRODUCTION USING Zymomanas mobilis AS FERMENTING ORGANISMS
Authors: Ruwa Abdulhamid Musa Ruwa , Grace A. F. , Hafsah M. A. , Kaltum U. M. , Ali A. A. , Adeboye M. M. , Musa I. , Falmata B. M. D. , Usman A. B. , Hauwa M. A. , Hosea S. H. , Aisha L. K. 
Published: May 2023

Bioethanol is a renewable energy produced from lignocellulosic biomass mainly by the fermentation process. It is used as an alternative to fossil fuel which doesn’t contribute to global warming. This research work was carried out to determining the potential of Neem tree leaves for bioethanol production. The process used in this study include pretreatment, hydrolysis fermentation and distillation. Hot water and Acid methods were used for the pretreatment. The hydrolysis of the substrate was carried out using Aspergillus niger for five days. Benedict test method was used to determine the reducing sugar concentration of the hydrolysate. The highest yield of 1500-2000 (mg/dl) was obtained equally for both the pre-treatment method. After hydrolysis, fermentation process was carried out for seven days using Zymomonas mobilis to ferment the hydrolysate. The fermented broth was separate using fractional distillation. Acid potassium dichromate was used to determine the concentration of the bioethanol produced. The results obtained shows that liquid hot water pretreatment produced the highest yield of 0.294±0.882 (mg/L) whereas alkaline method produced 0.282±.882 (mg/L) yield. Gas chromatography and mass spectroscopy analysis was also carried out to determine the presence of volatile compounds in the bioethanol produced. The highest volatile compound was Ethanol with 33.12% where Butyl Glycol was found to be least volatile compound with 6.22%. This result shows that Neem tree leaves is a good biomass for bioethanol production and pretreatment using Hot water method produced more bioethanol than Alkaline method of pretreatment.
COMPARATIVE EVALUATION ON THE POTENTIALS OF SHEEP RUMEN CONTENTS FOR BIOGAS GENERATION
Authors: Kaltum U. M. , Hafsah M. A. , Ruwa Abdulhamid Musa Ruwa , Grace A. F. , Ali A. A. , Adeboye M. M. , Musa I. , Falmata B. M. D. , Usman A. B. , Hauwa M. A. , Hosea S. H. , Abubakar B. T. 
Published: May 2023

Biogas refers to a gas produced by the biological breakdown of organic matter in the absence of oxygen. It is as a clean biofuel produced by microorganism during anaerobic digestion of organic matter. The study was carried out to determine the potentials of sheep rumen contents for biogas production through anaerobic digestion. Proximate analysis was carried out on the substrate. The results shows that nitrogen, potassium and phosphorus have 0.58 ± 0.02 (mg/ml), 425 ± 5.00 (mg/ml), and 2.57 ± 0.03 (mg/ml) respectively. After proximate analysis, four (4) local digesters with capacity of 500g tins were designed and used for the collection of gas via passage pipe systems. The digesters were used to digest the slurry (mixture of Sheep rumen content and water) which were mixed in the ratio of 2:1 for a period of eight weeks (56 days) retention time until the biogas reduced significantly. The pH values of the slurries were adjusted to neutral. The digesters were stirred thrice daily to avoid scum formation in the digesters and allow for easy escape of gas produced. The total average yield of the gas produced were 820 cm3, 1070 cm3, 780 cm3, and 660 cm3 for D1, D2, D3, and D4 respectively. Isolation of Microorganisms were caried during the production where B. subtilis, E. coli, P. aeruginosa, and S. aureus were found. Biogas production from organic wastes which is an eco-friendly, which helps to solve most countries energy crisis.