bluuebunny/crossref_metadata_2025_split huggingface dataset:
Direct 3D-bioprinting of hiPSC-derived cardiomyocytes to generate functional cardiac tissues
Authors: Esser Tilman U. , Anspach Annalise , Muenzebrock Katrin A. , Kah Delf , Schrüfer Stefan , Schenk Joachim , Heinze Katrin G. , Schubert Dirk W. , Fabry Ben , Engel Felix B. 
Published: June 2023

Abstract3D-bioprinting is a promising technology to produce human tissues as drug screening tool or for organ repair. However, direct printing of living cells has proven difficult. Here, we present a method to directly 3D-bioprint human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes embedded in a collagen-hyaluronic acid ink generating centimeter-sized functional ring- and ventricle-shaped cardiac tissues in an accurate and reproducible manner. The printed tissues contained hiPSC-derived cardiomyocytes with well-organized sarcomeres and exhibited spontaneous and regular contractions, which persisted for several months and were able to contract against passive resistance. Importantly, beating frequencies of the printed cardiac tissues could be modulated by pharmacological stimulation. This approach opens up new possibilities for generating complex functional cardiac tissues as models for advanced drug screening or as tissue grafts for organ repair or replacement.
The fungal pathogenUstilago maydistargets the maize corepressor TPL2 to modulate host transcription for tumorigenesis
Authors: Huang Luyao , Ökmen Bilal , Stolze Sara Christina , Kastl Melanie , Khan Mamoona , Hilbig Daniel , Nakagami Hirofumi , Djamei Armin , Doehlemann Gunther 
Published: June 2023

SummaryUstilago maydisis a biotrophic fungus that causes tumor formation on all aerial parts of maize.U. maydissecretes effector proteins during penetration and colonization to successfully overcome the plant immune response and reprogram host physiology to promote infection. In this study, we functionally characterized theU. maydiseffector protein Topless (TPL) interacting protein 6 (Tip6). We found that Tip6 interacts with the N-terminus of ZmTPL2 through its two EAR (Ethylene-responsive element binding factor-associated amphiphilic repression) motifs. We show that the EAR motifs are essential for the virulence function of Tip6 and critical for altering the nuclear distribution pattern of ZmTPL2. We propose that Tip6 mimics the recruitment of ZmTPL2 by plant repressor proteins, thus disrupting host transcriptional regulation. We show that a large group of AP2/ERF B1 subfamily transcription factors are misregulated in the presence of Tip6. Our study suggests a regulatory mechanism where theU. maydiseffector Tip6 utilizes repressive domains to recruit the corepressor ZmTPL2 to disrupt the transcriptional networks of the host plant.
Co-construction of performance indicators for a circular city and its relation to a local action net
Authors: Bekier Justyna , Parisi Cristiana 
Published: June 2023

PurposeThis study examines how circular economy (CE) performance indicators are constructed in an urban context characterised by a multitude of conflicting interests and visions of urban development. It explores the process of constructing a shared consensus about the performance indicators in conditions of low contractibility, where intervention objectives and outcomes are not easily quantifiable because the object is ambiguous and cannot be fully specified in advance.Design/methodology/approachThe construction of performance indicators at the urban level is examined through the lens of an action net. Using group interviews, observations and documentary analysis, this study investigates the case of a CE initiative in the city of Milan.FindingsThe study demonstrates that in cases of low contractibility, the development of CE solutions requires actions that span across organisational boundaries, organised in an action net. As the action net unfolds, it is closely knotted with the construction of performance indicators, indicating a co-constitutive relationship between the two processes.Originality/valueThis interdisciplinary study contributes to the public sector accounting literature by exploring the complexity of performance indicator construction at the urban level. It further recognises performance measurement in cities as a dynamic and flexible process, in which the interconnected actions and involvement of multiple actants shape the composition of the indicators.
Impact of entrepreneurial training on career outcomes: mediated by work passion in Pakistani business owners
Authors: Hussain Sajjad , Rafiq Muhammad , Mahmood Kashif , Nasir Sobia , Zahid Ayesha 
Published: June 2023

Purpose
Passion plays a vital role in entrepreneurship, and examining the role of training in passion development is a recent call. This study aims to examine the impact of entrepreneurial training on occupational commitment and career satisfaction of business owners based on goal content theory.

Design/methodology/approach
In doing so the role of harmonious passion is tested as a mediating mechanism. A three-wave time-lagged data were collected from 351 business owners operating in Punjab, Pakistan and were analyzed by using SmartPLS.

Findings
The findings suggested that entrepreneurial training had a positive impact on building entrepreneurial passion, and as a result, they were found to be more committed and satisfied with their entrepreneurial career. The research has theoretical and practical implications for the role of training in the development of entrepreneurial career outcomes.

Originality/value
Despite a growing interest in entrepreneurial passion, only few studies have explored the entrepreneurial training on occupational commitment and career satisfaction of business owners in context of Pakistan.
Is there a liability of foreignness or foreign privilege in developing nation compliance monitoring?
Authors: Florkowski Gary W. 
Published: June 2023

PurposeDrawing on the international business and game theory literature, this study assesses foreign firm treatment in the early stages of regulatory enforcement.Design/methodology/approachTreating regulation intensity as an exposure variable, negative binomial regression models were applied to firm-level data from 32 emerging markets (n = 15,331) to identify the determinants of inspection interactions. Robustness checks also were performed via variable substitutions for several predictors and an alternative form of statistical testing (i.e. Tobit regression, since it arguably better addresses dependent variables with corner solution responses).FindingsControlling for multiple organizational, regulatory and national characteristics, the findings are consistent with a foreign privilege, manifesting in reduced vulnerability to multiple encounters with labor inspection officials. Moreover, inward FDI stock was negatively related to the general probability of repeat interactions regardless of locus of ownership, an effect that was not moderated by stage of development or the regulatory influence of host interest groups. This collectively suggests that foreign firms not only are favored in compliance monitoring but also work post-entry to influence agencies to generally benefit business.Research limitations/implicationsMore comprehensive assessments were precluded given the lack of information on reasons for contact, citations and fines, and inspectorate reactions to company responses. Second, enforcement-risk management was measured indirectly since investors' internal dealings and actions toward officials are unavailable in secondary sources.Practical implicationsThese findings have important implications for social responsibility, suggesting CSR stakeholders need to track enforcement more closely and exert pressure where needed so rights are not sacrificed for economic development.Originality/valueThis study provides the most rigorous assessment to date of the role that firm, government and economic factors play in national inspection targeting. It also examined whether foreign owners pool and leverage their political influence to impact general inspection activity, a previously untested prospect.
Delivering societal impact through supply chain design: insights from B Corps
Authors: Rosca Eugenia , Taylor Kelsey M. 
Published: June 2023

PurposeThis paper examines how different configurations of societal impact are pursued by purpose-driven organizations (PDOs) and how these configurations align with the application of varying supply chain design (SCD) practices.Design/methodology/approachThis multi-method study uses quantitative data from 1588 B Corps and qualitative data from 316 B Corps to examine how PDOs align SCD with the pursuit of diverse types of societal impact. The authors first conduct a cluster analysis to group organizations based on the impact they create. Second, qualitative content analysis connects impact with enabling SCD elements.FindingsThe analysis of the five identified clusters provides detailed empirical insights on influencers, design decisions and building blocks adopted by PDOs to drive a range of societal impacts. Specifically, the nature of the impact pursued affects (1) whether a PDO will be more influenced by a need in the political environment or an opportunity in the industry environment, (2) the relative importance of the design of social flows versus material flows and (3) the need to develop new relational resources with beneficiaries versus leveraging existing capabilities to manage inter-firm processes.Originality/valueThis study responds to calls to disaggregate different dimensions of societal impact and examines the relationship between SCD and a breadth of sustainability impacts for different stakeholders. In doing so, the authors identify four SCD pathways organizations can follow to achieve specific societal impacts. This study is also the first to employ a supply chain perspective in the study of certified B Corps.
Why is India a popular destination for Bangladeshi medical tourists? A study based on perceived justice by Bangladeshi patients
Authors: Nabi Md. Noor Un , Khan Sarif Mohammad , Misbauddin S.M. , Fatema Kaniz 
Published: June 2023

Purpose
There is evidence of Bangladeshi citizens travelling to India to receive medical treatments, known as medical tourism. This study aims to explore the perceived justice dimensions of Bangladeshi patients towards domestic health care and the effects of these dimensions on their intention for outbound tourism to India.

Design/methodology/approach
Data from 307 Bangladeshi medical tourists were collected to test the proposed model. The data has been interpreted through the proposed model with covariance-based structural equation modelling in AMOS. To produce the results, the measurement model and structural model were examined.

Findings
The analysis confirmed the significant impact of procedural, informational and interpersonal justice dimensions on patients’ health-care experiences. However, the effect of distributive justice on patient experience has been found insignificant. The study also revealed a significant negative impact of patient satisfaction on outbound medical tourism intention. Thus, it raises concerns for the local medical service providers about improving patient satisfaction.

Practical implications
The findings of this paper can be applicable for health-care practitioners and policymakers in emerging countries to improve the bottlenecks of the health-care system for increasing patients’ service experiences and reducing the intention of patients for outbound medical tourism.

Originality/value
The research on perceived justice theory regarding the intention of medical tourism is limited. This research is one of the few studies to combine perceived justice theory with trust and medical tourism decision-making. Using the lens of perceived justice, this research argues that the decrease in perceived justice negatively affects the patients’ service experience, trust and loyalty to the service provider.
Exploring young consumer's adoption of secondhand luxury: insights from a qualitative study
Authors: Rathi Rubal , Jain Sheetal , Garg Ruchi 
Published: June 2023

PurposeThis study explores reasons for and against secondhand luxury (SHL) fashion adoption among young consumers in an emerging nation, India. As a trend, SHL has witnessed tremendous growth in the past few years, but scholarly interest remains scant.Design/methodology/approachDrawing from an interpretivist paradigm, this study uses an exploratory qualitative approach with 26 semi-structured interviews with SHL buyers, analyzed using NVivo software.FindingsThe findings shed significant light on value drivers and find support for status value, uniqueness value, quality value and monetary value, while adding the role of emotional value in reasons for SHL adoption. The results reveal an interesting trait of Indian consumers: price, fashion and celebrity association outweigh sustainability concerns, where an attitude–behavior gap is observed. Also, the findings add depth to risk perceptions as a major reason against SHL adoption.Originality/valueWhile most existing studies have only focused on the motivational drivers, this study offers in-depth insights into the growing SHL literature by drawing attention to the enablers and equally important inhibitors by applying the novel Behavioral Reasoning Theory. It also intends to enhance practitioner knowledge in understanding a culturally diverse market and developing strategies relevant to a new set of consumers. The study calls for SHL retailers to sensitize young consumers in India about the sustainability aspect of SHL consumption, which is currently less appreciated.
Investigating the effects of COVID-19 pandemic on Kuwait stock return: (A) symmetric time-varying evaluation
Authors: Kisswani Khalid M. 
Published: June 2023

PurposeThis study aims to explore the long- and short-run effects of daily confirmed cases of COVID-19 (Ct) on daily stock returns (Rt) for Kuwait. This is the first study that was applied to the case of Kuwait.Design/methodology/approachWe employed the autoregressive distributed lag (ARDL) model of Pesaranet al.(2001) and the nonlinear autoregressive distributed lag (NARDL) model of Shinet al.(2001) for daily data over the period March 2020 to August 2021.FindingsThe findings first document the existence of a long-run relationship (cointegration). Second, the findings of the ARDL model show a significant positive long-run effect of daily confirmed cases of COVID-19 (Ct) on daily stock returns (Rt) but a significant negative short-run effect. As for the NARDL model, the findings showed that the increase and decrease of daily confirmed cases of COVID-19(Ct−1+,Ct−1−)have symmetric long-run effects on daily stock returns but asymmetric short-run effects. Finally, the vector error correction model causality test shows significant long- and short-run unidirectional causality running from daily confirmed cases of COVID-19 (Ct) to daily stock returns (Rt).Originality/valueTo the best of the author’s knowledge, this is the first study that was applied to the case of Kuwait.
Audit partner industry specialization and audit report lag: does changing in the audit reporting requirements matter?
Authors: Mnif Yosra , Cherif Imen 
Published: June 2023

Purpose
This study aims to examine the relationship between the individual auditor’s industry specialization and the audit report lag (hereafter ARD). Further, it explores whether changing in the audit reporting requirement (i.e. the adoption of ISA701) influences the auditor’s industry specialization effect on the ARD.

Design/methodology/approach
A large data set of companies listed on the NASDAQ OMX Stockholm over the period 2010–2019 has been analyzed. Least squares regressions have been estimated to provide empirical evidence for the researched hypotheses.

Findings
The research findings indicate that the ARD is shorter for client firms audited by an industry specialist audit partner. Testing for the moderating role of changing in the auditing reporting regulation on the relation between the audit partner’s industry specialization and the ARD, the authors reveal that all client firms (except client firms with industry specialist audit partners) experienced an increase in the ARD. Overall, the baseline regression findings are found to be robust to the endogenous auditor choice and multiple measures of both the ARD and the auditor’s industry specialization.

Originality/value
This paper provides novel evidence on the relationship between the audit reporting lag and industry specialization from the individual auditor perspective, an issue that has hitherto been unexplored. The regression results further contribute to the upsurge debate about the consequences of changing in the audit reporting model by providing consistent support for the importance of industry specialization of the audit partner in minimizing costs derived from the former requirement.
Exploring folk songs to educate for resilience
Authors: Albacete-Maza Juan , Fernández-Cano Antonio , Callejas Zoraida 
Published: June 2023

PurposeCovid-19 pandemic, war, climate emergency and other recent challenges are inflicting tremendous stress to youth. However, death and tragedy are nowadays considered taboo, as there is generally no standardized nor naturalized discussion on the subject, especially with young people. The current multi-crisis scenario is intensifying the need to incorporate an education on tragedy and resilience in our learning systems. In this context, it is necessary to find suitable teaching resources for this educational challenge that are attractive, entertaining and suitable for children and youth. A resource that meets all these requirements are children’s folk songs (CFSs). Apart from the intrinsic educational potential of music, folk songs have a simplicity and musicality that make them an ideal teaching resource. Considering their oral historical transmission, their survival confirms the attraction that this type of composition causes on children. However, to consider CFSs as an adequate resource to carry out an education for death and tragedy, it is necessary to study whether they present a non-negligible proportion of tragic passages and with enough variety of themes. This paper aims to address the study of the presence of explicit tragic content in Spanish CFSs and thus could be considered a cultural resource with transformative educational potential to develop resilience capabilities on the face of tragedy.Design/methodology/approachAn analysis of lyrics of 2,558 Spanish CFSs is presented, using a manual content analysis as well as a computerized content analysis with the aim of identifying the tragic component of these songs and, thereby, assessing their pedagogical potential as a transformative educational resource.FindingsThe results obtained show a considerable presence of death and tragedy (19.78%) and a variety of tragedy dimensions. CFSs have been transmitted orally not only as a ludic resource, but also to prepare children for life (and death). The results show the complementarity of both analyses to avoid subjectivity while considering the underlying meanings of the songs.Originality/valueThis task had previously not been approached in an automated manner in the literature, nor there had been a similar study with a sample of this magnitude. The outcomes obtained show the considerable presence of tragedy in Spanish CFSs and emphasize the interest of this currently undervalued didactic resource.
Design optimization of 3D printed flow path plates in high-performance bioethanol fuel cells
Authors: T.S. Manikandamaharaj , B.M. Jaffar Ali 
Published: June 2023

Purpose
Effective performance of a direct ethanol fuel cell (FC) stack depends on the satisfactory operation of its individual cells where it is always challenging to manage the temperature gradient, water flow and distribution of reactants. In that, the design of the bipolar fuel flow path plate plays a vital role in achieving the aforementioned parameters. Further, the bipolar plates contribute 80% of the weight and 30%–40% of its total cost. Aim of this study is to enhance the efficiency of fuel to energy conversion and to minimize the overall cost of production.

Design/methodology/approach
The authors have specifically designed, simulated and fabricated a standard 2.5 × 2.5 cm2 active area proton exchange membrane (PEM) FC flow path plate to study the performance by varying the flow fields in a single ladder, double ladder and interdigitated and varying channel geometries, namely, half curve, triangle and rectangle.

Findings
Using the 3D PEMFC model and visualizing the physical and electrochemical processes occurring during the operation of the FCs resulted in a better-performing flow path plate design. It is fabricated by using additive manufacturing technology. In addition, the assembly of the full cell with the designed flow path plate shows about an 11.44% reduction in total weight, which has a significant bearing on its total cost as well as specific energy density in the stack cell.

Originality/value
Simultaneous optimization of multiple flow path parameters being carried out for better performance is the hallmark of this study which resulted in enhanced energy density and reduced cost of device production.
Efficient toolpath planning for collaborative material extrusion machines
Authors: Bacciaglia Antonio , Ceruti Alessandro 
Published: June 2023

Purpose
Timing constraints affect the manufacturing of traditional large-scale components through the material extrusion technique. Thus, researchers are exploring using many independent and collaborative heads that may work on the same part simultaneously while still producing an appealing final product. The purpose of this paper is to propose a simple and repeatable approach for toolpath planning for gantry-based n independent extrusion heads with effective collision avoidance management.

Design/methodology/approach
This research presents an original toolpath planner based on existing slicing software and the traditional structure of G-code files. While the computationally demanding component subdivision task is assigned to computer-aided design and slicing software to build a standard G-code, the proposed algorithm scans the conventional toolpath data file, quickly isolates the instructions of a single extruder and inserts brief pauses between the instructions if the non-priority extruder conflicts with the priority one.

Findings
The methodology is validated on two real-life industrial large-scale components using architectures with two and four extruders. The case studies demonstrate the method's effectiveness, reducing printing time considerably without affecting the part quality. A static priority strategy is implemented, where one extruder gets priority over the other using a cascade process. The results of this paper demonstrate that different priority strategies reflect on the printing efficiency by a factor equal to the number of extrusion heads.

Originality/value
To the best of the authors’ knowledge, this is the first study to produce an original methodology to efficiently plan the extrusion heads' trajectories for a collaborative material extrusion architecture.