bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appropriate indications for laparoscopic repeat hepatectomy
Authors: Masuda Takashi , Endo Yuichi , Amano Shota , Kawamura Masahiro , Fujinaga Atsuro , Kawasaki Takahide , Kawano Yoko , Hirashita Teijiro , Ohta Masayuki , Inomata Masafumi 
Published: April 2023

Abstract
Background: Laparoscopic repeat hepatectomy (LRH) has increased, but appropriate indications for LRH are unclear. This study aimed to clarify appropriate indications for LRH.
Methods: We retrospectively compared surgical outcomes between open RH (ORH) (n=57) and LRH (n=40) groups. To detect difficult cases of complete pure LRH, we examined patients with unplanned intraoperative hand-assisted laparoscopic surgery (HALS)/open conversion (n=6).
Results: In the LRH versus ORH group, as previous hepatectomy, laparoscopic (75% vs. 12%, p<0.001) and Hr0 (73% vs. 37%, p=0.002) were more frequently performed, and as RH procedure, Hr0 (88% vs. 47%, p=0.0002)was more frequently performed. S1 tumor cases were higher in ORH group (11% vs. 0%), but S2-6 cases were higher in LRH group(73% vs. 49%) (p=0.02). In LRH group, compared to the pure LRH patients, HALS/open conversion patients underwent significantly more previous hepatectomy with Hr2-3 (33% vs. 2.9%, p=0.033) and more RH procedures with HrS (33% vs. 2.9%, p=0.03). All LRH requiring a second hepatic hilar approach were HALS conversions.
Conclusion: Appropriate indications for LRH were previous hepatectomy was laparoscopic Hr0, and RH procedure was Hr0 for S2-6 tumor location. When RH is more than HrS requiring a second hepatic hilar approach, LRH should not be selected due to the high possibility of HALS/open conversion.
Un-differential processing of COSMIC-2 radio occultation measurements with 1-Hz LEO clock corrections
Authors: Guo Sheng , Zhang Shaocheng , Meng Xiangguang , Wu Yunlong , Lou Yidong , Lin Jian 
Published: April 2023

Abstract
Precise isolating atmospheric excess phase (AEP) is the fundamental work of Global Navigation Satellite System (GNSS) radio occultation technique towards reconstructing on the refractivity and other meteorological profiles. Currently, the COSMIC-2 satellites AEP products from University Corporation for Atmospheric Research (UCAR) were calculated by conventional single-differential approach at cost of complicating the processing and also amplified the excess phase noise. This study provided a strengthened un-differential method for COSMIC-2 AEP calculation such that the interpretation of raw occulting phase data could be enriched. The vital bias, receiver clock offset, was modeled and calibrated at 1s sampling via pre-processing of LEO precise orbit determination, which took both two antennas’ observations into estimator for intensifying orbit and clock precision. After combining the un-differential method with 1s LEO receiver clock corrections, COSMIC-2 AEP was calculated and collected to retrieve the refractivity profiles for statistical validation. Analyzation of 2579 RO profiles indicates that the mean bias of our results against COSMIC-2 official refractivity profiles were below 0.2% at height above 10km. Furthermore, external reference of European Centre for Medium-Range Weather Forecasts (ECMWF) analysis data was adopted for revealing the characteristics of bias and investigating the advantage of un-differential approach. Validation indicates that the standard deviation (STD) of un-difference derived refractivity against co-located referred profiles were around 1.17% and 1.28% for GPS and GLONASS occultations at altitude below 35km, appearing bias less than 0.04% against single difference method derived. The un-difference processing also shows higher accuracy than single difference in the lower troposphere. Hence, the proposed UD processing for COSMIC-2 radio occultation retrieval is feasible when the 1s LEO clock offsets were estimated for correction.
Robotic Surgery Perception and Attitude Among Medical Students in the Gulf Countries: A Multinational Cross-Sectional Study
Authors: Mousa Ahmed Hafez , Nukaly Houriah Yasir , Abujamai Jakleen Ziyad , Mohamed Rawan Elwalid Ali , AlShehabi Nagam , Duvuru Ruthwik , Ennab Farah , Nawaz Faisal A , Ahmed Ruqayyah Ali , Mosalli Rafat , Alshanberi Asim Muhammed , Ali Ehab A. Abo 
Published: April 2023

Abstract

Background:Robotic surgery comprises surgical procedures performed via robotic assistance. Recently, 75% more surgical robotic systems were installed in the United States’ hospitals. Saudi Arabia was the first regionally to introduce robotic surgery in 2003. Our study aims to compare and assess medical students’ knowledge and attitude on robotic surgery in the Gulf Region.Methods:This descriptive cross-sectional study assessed medical students across Kingdom of Saudi Arabia (KSA), United Arab Emirates (UAE) and Qatar. Our questionnaire evaluated demographical background, knowledge on robotic surgery, and lastly attitude towards robotic surgery.Results:The 278 participants (UAE: 144, KSA: 99, and Qatar: 35) were mostly female (66.9%), preclinical students (56.1%) and local (53.2%). Most UAE participants (86.8%) were aware of local robotic surgery applications, while most KSA (62.6%) and Qatar (82.9%) participants were not sure. Most KSA (60.6%), UAE (89.6%) and Qatar (68.6%) students correctly defined robotic surgery. Most participants from KSA felt neutral (36.3%) or agreed (33.3%) to use robotic surgery in clinical practice, while majority of UAE participants (57.6%) strongly agreed, and Qatar participants (51.4%) agreed. In addition, KSA respondents were more neutral (42.4%) on investing into robotic surgeries than UAE and Qatar participants.Conclusion:Most UAE participants were aware of local robotic surgery applications, while most KSA and Qatar participants were not sure. Mostmedical students in the Middle East had high level of knowledge on robotic surgery and its characteristics. However, attitudes on applicability of robotic surgery varied between positive and neutral outlooks depending on the country.
Green Cloud Computing Adoption Challenges and Practices: A Client's Perspective based Empirical Investigations
Authors: Ahmad Ashfaq , Khan Siffat Ullah , Khan Rafiq Ahmad , Alwageed Hathal Salamah , Al-Atawi Abdullah A. 
Published: April 2023

Abstract
Context
Over the last decade, the widespread adoption of cloud computing has spawned a new branch of the computing industry, known as green cloud computing. Cloud computing is improving, and data centers are increasing at regular frequencies to meet the demands of users. Cloud providers, on the other hand, pose major environmental risks because massive data centers use a large amount of energy and leave a carbon footprint. One possible solution to this issue is the use of green cloud computing. However, clients face significant difficulties in adopting green cloud computing.
Objective
This study aims to understand the problems faced by client organizations while considering green cloud computing. In addition, this study aims to empirically identify the solution to the challenges faced by green cloud computing practitioners.
Method
A questionnaire survey approach was used to get insight into green cloud computing practitioners concerning the challenges they faced and their solutions.
Results
Data were obtained from sixty-nine professionals in green cloud computing. The results revealed that "lack of quality of service", "lack of dynamic response", and "lack of services to satisfy client's requirements" are critical for green cloud computing. In addition, sixty-three practices for addressing the challenges in green cloud computing are also identified.
Conclusion
The identified challenges and practices of green cloud computing will benefit the client organizations to update and revise their process to consider green cloud computing. In addition, it will also assist vendor organizations in developing, planning, and managing systems concerning client satisfaction.
Verification of the existence of copper-based antifouling paint particles in the sea and their implications for marine microplastic degradation
Authors: NAKATANI Hisayuki , YAMASHIRO Kaito , UCHIYAMA Taishi , MOTOKUCHO Suguru , DAO Anh Thi Ngoc , KIM Hee-Jin , YAGI Mitsuharu , KYOZUKA Yusaku 
Published: April 2023

Abstract
Marine microplastics (MP) and microdebris were retrieved from the five sampling stations between Nagasaki port and Goto Island and were classified into six types. Three of these types, MP (A), Si-based (B), and Cu-based (C) paint particles, were predominant. Type C had no depth dependence, regardless of the presence of cuprous oxide with high specific gravity. The dominant size of type C was less than 10 µm and contained 30 to 50 mol% of Cu content. The long stay behavior of type C suggested that it had implications for degrading type A. To clarify this, polypropylene (PP) film samples containing cuprous oxide were prepared, and their accelerated degradation behavior in seawater was investigated using the advanced oxidation process method using the sulfuric acid radical initiator in seawater of different salinity concentrations. Infrared spectroscopy revealed the formation of a copper soap compound in seawater. Scanning electron microscopy/energy-dispersive X-ray spectroscopy analysis indicated that the chemical reactions between Cl− and cuprous oxide produced Cu+ ions. Changes in the number of polymer chain scissions were investigated at various salinity concentrations of seawater. These findings confirm that Cu+ species promote PP autoxidation.
Cuprotosis Clusters Predicts Prognosis and Immunotherapy Response in Low-grade glioma
Authors: Zhu Wenjun , Fu Min , Li Qianxia , Chen Xin , Li Xiaoyu , Luo Na , Tang Wenhua , Yang Feng , Chen Ziqi , Zhang Yiling , Zhang Yuanyuan , Peng Xiaohong , Hu Guangyuan 
Published: April 2023

Abstract
Cuprotosis, a new cell death mode, has recently received increasing attention. However, the role of cuprotosis in low-grade glioma (LGG) remains unclear. In this study, we explored the relationship of cuprotosis with LGG patient prognosis and immune status. We divided LGG patients into cuprotosis clusters A and B based on the expression of 18 cuprotosis genes in LGG patients. The prognosis of patients in cuprotosis cluster A was better than cuprotosis cluster B. Cuprotosis clusters showed different immune cell infiltration and biological functions. We screened the differentially expressed genes (DEGs) between the different cuprotosis clusters and identified 6 DEGs (TNFRSF11B, METTL7B, SSTR2, OXTR, CDKN2C, and H19) to construct a cuprotosis-related prognostic signature to predict the prognosis of LGG patients through univariate cox-lasso-multivariate cox regression analysis. The signature split LGG patients into two risk groups. High-risk group showed significantly shorter overall survival (OS) time than low-risk group in the training group, internal and external validation groups. The nomogram further precisely predicted patients' 1, 3 and 5-year OS. The Sankey diagram visually displayed the correspondence of different clusters with risk scores and survival status. Similarly, we also found the relationship of tumor microenvironment (TME) infiltration and tumor mutation burden (TMB) with risk scores, and the high-risk group might benefit more from immunotherapy. In conclusion, our study highlighted the significant role of cuprotosis in LGG prognosis and TME infiltration. The cuprotosis-related prognostic signature would help us predict the prognosis of LGG patients and understand the LGG immune infiltration characterization, providing potential molecules for further molecularly targeted therapies and immunotherapeutic interventions in LGG.
Serum thiamine levels was relative factors in the incidence of readmission due to heart failure
Authors: Watanabe Shingo 
Published: April 2023

Abstract
Background and Aims
Previous studies have reported that 5-91% of patients with heart failure have thiamine deficiency. With the aging of heart failure patients, the number of heart failure patients with thiamine deficiency may increase. It is important to know the prevalence and clinical characteristics of heart failure patients with thiamine deficiency.
The purpose of our study is to investigate the prevalence and clinical characteristics of thiamine deficiency in patients with heart failure.
Methods and Results
The subjects were 256 cases who were admitted to our hospital for acute heart failure. All patients were classified into two groups, a thiamine deficient group (TD group N=72) and a normal thiamine group (NT group N=184), with the serum vitamin 24 ng / ml, which is the standard value in Japan, as the cutoff value. The clinical features and outcomes of both groups were investigated. The endpoint was set to one-year of cardiac death and readmission due to heart failure.
Of all 256 cases, 72 (28.1%) had thiamine deficiency.
The TD group had a significantly higher incidence of one-year cardiac death (25.0% VS 13.0% P=0.02) and readmission due to heart failure (38.9% VS 23.9% P=0.01)
Multivariate logistic regression analysis revealed that serum thiamine levels was relative factors in the incidence of readmission due to heart failure.
Conclusion
Thiamine deficiency is not uncommon in patients with heart failure.
Patients with heart failure who have thiamine deficiency have a high incidence of readmission due to heart failure, so treatment aimed at preventing readmission is necessary.
Distribution of normalized pulmonary transit time per pathology in a population of routine CMR examinations
Authors: Jossart Adrien , Gerber Bernhard , Houard Laura , Pilet Bernard , O'Connor Sean , Gilles Raymond 
Published: April 2023

Abstract
Introduction: Pulmonary Transit Time (PTT), defined as the time required for a contrast bolus to pass from the right ventricle to the left ventricle, is a surrogate for noninvasive preload assessment. It is used in different imaging modalities: pulmonary angiography, echocardiography and cardiac magnetic resonance (CMR).
Purpose: Many recent studies have highlighted the prognostic value of PTT. Therefore, we sought to evaluate PTT in a consecutive cohort of patients undergoing CMR.
Methods: We retrospectively evaluated PTT normalized for heart rate in 278 patients (66% male, mean age 58±11 years) who underwent CMR between August 2017 and November 2021 with a diagnosis of dilated cardiomyopathy, infarct, hypertrophy, valvular, myocarditis, other pathology or no pathology (“normal”).
Results: Normalized pulmonary transit time (nPTT) was higher in men than in women (8.4 ± 1.3 beats vs 7.5 ± 1.1 beats, p = 0.002) in the “normal” group. nPTT was moderately correlated with left ventricular end-diastolic volume (LVEDV) (r² = 0.19 ; p < 0.001), left ventricular end-systolic volume (LVESV) (r² = 0.34 ; p < 0.001) and left ventricular ejection fraction (LVEF) (r² = 0.29 ; p < 0.001). nPTT was significantly higher in patients suffering from dilated cardiomyopathy (11.3 ± 5.4 beats ; p < 0.001), infarct (9.5 ± 2.9 beats ; p < 0.001) or valvular disease (9.5 ± 3.1 beats ; p = 0.006) than in patients included in the “normal” group (7.9 ± 1.3 beats).
Conclusion: nPTT is a novel major surrogate for the preload status of the patient. Its value depends on gender and type of pathology.
Optimal bounds for complete elliptic integral from the quasi-arithmetic mean and Seiffert-like mean
Authors: Shi Yong-Guo , Li Na 
Published: April 2023

Abstract
We give the new double inequalities for the quasi-arithmetic mean and Seiffert-like mean. As applications, two new optimal bounds are presented for the complete elliptic integral of the second kind. And numerical comparisons illustrate that some bounds of our results are better than before.
AMS(2020) subject Classification: 26E60, 33C75, 26D20.
Monitoring Mangrove Forest Degradation in the Sunderban Region of India using Remote Sensing Techniques: Implications for CO 2 Absorption and Surface Energy Balance from 2000-2020
Authors: Maske Ambadas Bandu 
Published: April 2023

Abstract
The study uses novel remote sensing approach for understanding the changes in mangrove forest of Sunderban region of India. The study tried to estimate the changes in carbon emissions using GIS and remote sensing. The study quantifies the changes in different heat fluxes of surface energy balance i.e., net radiations, ground heat flux, latent heat flux. Unavailability of real time atmospheric profile data is the major limitation of study. study presents an analysis of the changes in carbon emissions, energy fluxes, and land-use and land-cover (LULC) in the Sunderban forest from 2000 to 2020. The results show a significant loss of mangroves, which has led to a decline in carbon stocks and an increase in CO2 emissions. Changes in the energy fluxes, particularly the decrease in latent heat flux, were found to be associated with the reduction in the area under mangrove. The LULC analysis reveals changes in the surface temperature due to the reduction in vegetation cover, which has implications for the local and regional climate. The findings underscore the urgent need for conservation and restoration efforts to protect the vital ecosystem services provided by mangrove forests and mitigate the adverse effects of climate change.
The significance of calibration to the quantum-mechanical description of physical reality
Authors: Krechmer Ken 
Published: April 2023

Abstract
This paper is a response to the EPR paper titled: "Can quantum-mechanical description of physical reality be considered complete?", published in Physical Review in 1935. A quantum-mechanical (QM) measure function describes a distribution of local results, while each experimental measurement process produces one result as exact as allowed by a measuring apparatus calibrated to a non-local unit standard. Repeating experimental measurements produces a Gaussian distribution of measurement results. These QM and experimental measurement result distributions can be compared. To compare a QM measure function describing a distribution of eigenvectors to a distribution of repetitive experimental measurement results, it is necessary to determine, by calibration, the precision of the eigenvectors to the same standard as the experimental results, because each eigenvector evidences uncertainty relative to a standard. When the calibration process is recognized as formal as well as empirical, QM measure function and experimental measurement process results are unified.
Automatic Test Data Generation based on the Prime Path Coverage Criterion: A Grouping-based GA Approach
Authors: Damia Amirhossein , Esnaashari Mehdi , Parvizimosaed Mohammadreza 
Published: April 2023

Abstract
Software testing is the process of running an application with the goal of finding bugs and subsequently improving its quality. Software testing, as a key process, plays a role in ensuring the quality of software systems. Testing is currently considered an industry in the field of software. Given that about 40% of the cost of producing any software is spent on testing, creating tools for automatically generating test data will significantly reduce the current costs of software development. This process can be considered an optimization problem, and thus, search algorithms can be used for tackling it. The Genetic Algorithm (GA) is one of the widest algorithms in this field. In this paper, we have proposed a novel GA approach, called Group-based GA (G-GA), which differs from the standard GA algorithm in the following ways. First of all, a new fitness function has been utilized that uses search space information to guide the population. The population is divided into four groups, each of which is updated according to its fitness level. Finally, in the proposed algorithm, the selection operator has been omitted and thus, the algorithm has less complexity and calculations than the standard GA. Also, the proposed algorithm considers a good level of exploration and exploitation at each step. Experiments have shown that the proposed G-GA method, in terms of the convergence speed and the search time, significantly outperforms the basic GA, its variations, PSO, Tabu Search, and Simulated Annealing.
Elucidation of the mechanisms of human cathelicidin-derived antimicrobial peptides (LL-37 and its truncated LL-31) against Burkholderia pseudomallei
Authors: Tun Wonn Shweyi Thet , Phophetleb Onanong , Klaynongsruang Sompong , Daduang Sakda , Taweechaisupapong Suwimol , Patramanon Rina 
Published: April 2023

Abstract
Melioidosis is an endemic disease caused by Burkholderia pseudomallei found in tropical areas. The bacterium is intrinsically resistant to conventional antibiotics, making treatment difficult. Cathelicidin-derived peptides LL-37, and its truncated LL-31 played a crucial role in innate immune defense against infected microorganisms. LL-31 showed superior killing activity than LL-37 in reducing bacteria viability, combination with antibiotic ceftazidime (CAZ), outer and inner membrane permeabilization, membrane depolarization, and affinity binding to lipopolysaccharide (LPS) of B. pseudomallei. Both peptides had similar content of alpha-helical structure. This study provided insights into the molecular mechanisms of LL-37 and its truncated form, LL-31. By utilizing the knowledge gained from this study, researchers may be able to improve treatment options and help combat the spread of antibiotic-resistant bacteria.
Isolation and characterization of two glycolipopeptids biosurfactants produced by a Lactobacillus plantarum strain isolated from green olive curing water
Authors: AMMAR Ameni Ben , BOUASSIDA Mouna , BOUALLEGUE Amir , FOURATI Nada , Gerardi Gisela , Muñiz Pilar , Benito Jose Manuel , GHRIBI Dhouha 
Published: April 2023

Abstract
Microbial surfactants are natural amphiphilic compounds with high surface activities and emulsifying properties. Due to their structural diversity, low toxicity, biodegradability, and chemical stability in different conditions, these molecules are potential substitutes for chemical surfactants; their interest has grown significantly over the last decade. The current study focuses on the isolation, identification, and characterization of a lactic acid bacteria that produces two forms of biosurfactants. The OL5 strain was isolated from green olive fermentation and identified using MALDI/TOF and ADNr16S amplification. Emulsification activity and surface tension measurements were used to estimate biosurfactant production. The two biosurfactants derived from L. plantarum OL5 presented good emulsification powers in the presence of various oils. They were also shown to have the potential to reduce water surface tension from 69 mN/m to 34 mN/m and 37 mN/m within a critical micelle concentration (CMC) of 7 mg/ml and 1.8 mg/ml, respectively, for cell bound and extracellular biosurfactants. Thin layer chromatography (TLC) and FT-IR were used to analyze the composition of the two biosurfactants produced. the obtained data revealed that the two biomolecules consist of a mixture of carbohydrates, lipids and proteins. We demonstrated that they are two anionic biosurfactants with glycolipopeptide nature which are stable in extreme conditions of temperature, pH and salinity.