bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphological changes after open lumbar microdiscectomy at 2-year follow-up
Authors: Şimşek Abdullah Talha , Baysal Begümhan , Adam Baha Eldin , Çalış Fatih , Topçam Arda , Demirkol Mahmut , Doğan Mahmut Bilal , Binguler Ayse Hande Erol , Karaarslan Numan , Balak Naci 
Published: August 2023

BACKGROUND: It is known that a possible decrease in disc height (DH) and foraminal size after open lumbar microdiscectomy (OLM) may cause pain in the long term. However, there is still insufficient information about the short- or long-term pathoanatomical and morphological effects of microdiscectomy. For example, the exact temporal course of the change in DH is not well known. OBJECTIVE: The purpose of this study was to examine morphological changes in DH and foramen dimensions after OLM. METHODS: In patients who underwent OLM for single-level lumbar disc herniation, MRI scans were obtained before surgery, and at an average of two years after surgery. In addition to DH measurements, foraminal area (FA), foraminal height (FH), superior foraminal width (SFW), and inferior foraminal width (IFW), were measured bilaterally. RESULTS: A postoperative increase in DH was observed at all vertebral levels, with an average of 5.5%. The mean right FHs were 15.3 mm and 15.7 mm before and after surgery, respectively (p= 0.062), while the left FHs were 14.8 mm and 15.8 mm before and after surgery (p= 0.271). The mean right SFW was 5.4 mm before surgery and 5.7 mm after surgery, while the mean right IFW ranged from 3.6 mm to 3.9 mm. The mean left SFW was 4.8 mm before surgery and 5.2 mm after surgery, while the mean left IFW ranged from 3.5 mm to 3.9 mm. Before surgery, the FAs were, on average, 77.1 mm2 and 75.6 mm2 on the right and left sides, respectively. At the 2-year follow-up, the mean FAs were 84.0 mm2 and 80.2 mm2 on the right and left sides, respectively. CONCLUSIONS: Contrary to prevalent belief, in patients who underwent single-level unilateral OLM, we observed that there may be an increase rather than a decrease in DH or foramen size at the 2-year follow-up. Our findings need to be confirmed by studies with larger sample sizes and longer follow-ups.
Anxiety in Parkinson’s Disease Is Associated with Changes in Brain Structural Connectivity
Authors: Carey Guillaume , Viard Romain , Lopes Renaud , Kuchcinski Gregory , Defebvre Luc , Leentjens Albert F.G. , Dujardin Kathy 
Published: August 2023

Background: Anxiety in Parkinson’s disease (PD) has been associated with grey matter changes and functional changes in anxiety-related neuronal circuits. So far, no study has analyzed white matter (WM) changes in patients with PD and anxiety. Objective: The aim of this study was to identify WM changes by comparing PD patients with and without anxiety, using diffusion-tensor imaging (DTI). Methods: 108 non-demented PD patients with ( n = 31) and without ( n = 77) anxiety as defined by their score on the Parkinson Anxiety Scale participated. DTI was used to determine the fractional anisotropy (FA) and mean diffusivity (MD) in specific tracts within anxiety-related neuronal circuits. Mean FA and MD were compared between groups and correlated with the severity of anxiety adjusted by sex, center, Hoehn & Yahr stage, levodopa equivalent daily dosage, and Hamilton depression rating scale. Results: Compared to patients without anxiety, PD patients with anxiety showed lower FA within the striato-orbitofrontal, striato-cingulate, cingulate-limbic, and caudate-thalamic tracts; higher FA within the striato-limbic and accumbens-thalamic tracts; higher MD within the striato-thalamic tract and lower MD within the striato-limbic tract. Conclusions: Anxiety in PD is associated with microstructural alterations in anxiety-related neuronal circuits within the WM. This result reinforces the view that PD-related anxiety is linked to structural alteration within the anxiety-related brain circuits.
Long term remineralizing effect of casein phosphopeptide amorphous calcium phosphate in white spot lesions: A systematic review and meta-analysis
Authors: AlBuraiki Meisam Jehad , Ingle Navin Anand , Baseer Mohammad Abdul , Al Mugeiren Osamah M. , Minervini Giuseppe 
Published: August 2023

BACKGROUND: White spot lesions (WSLs) appear as white, opaque areas on the teeth and are caused by a demineralization of the enamel. OBJECTIVE: The purpose of this systematic review and meta-analysis was to determine whether casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has beneficial effects on WSLs and provides remineralizing benefits that are superior to those of placebo or no treatment. METHODS: Following a thorough analysis of the literature across major online sources, 103 papers – 54 of which underwent in-depth evaluation – were found. We used inclusion and exclusion criteria to choose research articles that were appropriate for our review. RESULTS: 10 papers met this review’s requirements and were subsequently included. As compared to the controls, CPP-ACP demonstrated increased efficacy in treatment of WSLs in terms of remineralisation and other parameters which included microhardness tests and enamel surface roughness. The forest plots present the results of meta-analyses comparing the effect of CPP-ACP versus control/other agents on white spot lesions (WSLs). In terms of odds ratios (OR), CPP-ACP showed a small increase in the odds of WSLs compared to control/other agents. In-vitro studies showed no significant difference in relative risk (RR) between CPP-ACP and control/other agents. Randomized control trials indicated a small increase in the risk of WSLs with CPP-ACP treatment, but the overall effect was not statistically significant. CONCLUSION: There was evidence to support the use of CPP-ACP over other agents for WSL prevention or treatment, but further research is needed to confirm these findings.
Asociación poco frecuente del complejo OEIS con un defecto diafragmático
Authors: Torres Paola Catalina , Montaña-Jiménez Lina Paola , Ramirez-Corredor Ayelet , Vargas Vaca Yaris Anzully , Zarante Ignacio , Lopez Cruz Ruth Liliana 
Published: August 2023

El complejo OEIS (onfalocele, extrofia cloacal, ano imperforado y defectos espinales) forma parte de los defectos de pared abdominal. Es una entidad infrecuente, que conlleva alta morbimortalidad y requiere de manejo multidisciplinario. Objetivo: Reportar un caso de asociación poco frecuente entre el complejo OEIS y hernia diafragmática; discutir su patogénesis y posible asociación con otras malformaciones de línea media. Caso Clínico: Neonato pretérmino, con diagnóstico antenatal de onfalocele. Al nacer destacó onfalocele gigante con amnios íntegro que contenía todo el hígado y asas, extrofia vesical con vejiga abierta y orificios uretrales expuestos, útero didelfo, epispadias, no se palparon gónadas, mediante imágenes se logró evidenciar extrusión de los tejidos blandos de pelvis, hernia diafragmática izquierda (Bochdalek), malformaciones óseas, mielomeningocele y mielocistocele. Con dichos hallazgos, se planteó complejo OEIS con presentación simultánea de pentalogía Cantrell o deleción 1p36, en el estudio genético se descartaron cromosomopatías, pero no se pudo completar estudio más específico. Se realizó colostomía, cierre de cloaca y afrontamiento a línea media de placa vesical, con adecuada evolución postoperatoria. Dada estabilidad respiratoria, se difirió corrección quirúrgica de hernia diafragmática. Se dio de alta después de una larga hospitalización, falleciendo por patología respiratoria aguda intercurrente. Conclusiones: Dentro de las asociaciones clínicas del complejo OEIS la hernia diafragmática es infrecuente, lo que podría corresponder a una forma inusual del complejo, debido a presentación simultánea con pentalogía Cantrell o deleción 1p36. A pesar de ser una malformación de presentación esporádica, es importante tener conocimien- to de sus características y variantes.
Anemia y comunicación verbal efectiva en niños y niñas de 9 a 36 meses
Authors: Reátegui-Díaz Marcelo , Bernabé-Barreto Antouannet , Vilchez-Villarreal Nicole , Noriega-Arce Nicole , Romaní-Romaní Franco Romani 
Published: August 2023

La comunicación verbal efectiva (CVE) es la capacidad para entender y decir lo que sienten y piensan los niños(as), lo cual podría verse afectada por la anemia. Objetivo: determinar la asociación entre anemia y CVE a nivel comprensivo y expresivo en niños(as) de 9 a 36 meses. Sujetos y Método: estudio basado en la Encuesta Demográfica y de Salud Familiar 2020 del Perú, de diseño transversal. Se seleccionaron mujeres con hijo(a) sin discapacidad de 9 a 36 meses, participantes del Módulo de Desarrollo Infantil Temprano, cuyo niño(a) tuviera hemoglobinometría. Se clasificó el grado de anemia según los niveles de hemoglobina: normal 11,0 a 14,0; leve 10,0 a 10,9; moderada 7,0 a 9,9 y severa < 7,0 g/dL. Dichas categorizaciones consideraron el nivel de hemoglobina ajustada por altitud. Para el análisis bivariado y multivariado se definió anemia como presente (hemoglobina < 11,0 g/dL) o ausente (≥ 11,0 g/dL). La CVE fue medida con “Battelle Development Instrument”, adecuada y validada para niños(as) peruanos. Su usó regresión logística binaria, donde la CVE fue la variable dependiente y anemia junto a otras covariables fue la independiente. Resultados: el 26,2% y 10,9% de niños(as) tuvo anemia leve y moderada-grave, respectivamente. La proporción de niños(as) con CVE sin riesgo según edad fue: 9 a 12 meses (76,6%), 13 a 18 meses (35,4%), 19 a 23 meses (25,6%) y 24 a 36 meses (55,3%). La asociación entre anemia y CVE no fue significativa en ninguno rango de edad. Las covariables asociadas a la CVE sin riesgo fueron: sexo (13-36 meses); alfabetismo materno (9-12 y 24-36 meses), lugar de residencia (24-36 meses) y administración de hierro en los últimos 12 meses (13-18 meses). Conclusiones: la anemia no es un factor asociado a la CVE de acuerdo con la edad, existirían otras rutas causales que pondrían en riesgo el desarrollo de la CVE.
Contabilidad de costes y procesos de producción de estructuras metálicas
Authors: Mayorga Ases Maria Jose , Velastegui Hernández Rommel Santiago , Mayorga Ases Leticia Abigail , Carranza Calero Diego Mauricio 
Published: August 2023

Introducción. La contabilidad de costes desempeña un papel crucial en la producción de estructuras de acero, proporciona información valiosa sobre la salud financiera de una empresa y ayuda a tomar decisiones informadas sobre la optimización de costes. El proceso de producción de estructuras de acero, la contabilidad de costes es especialmente importante debido a la complejidad de las operaciones de fabricación. La contabilidad de costes desempeña un papel importante en la toma de decisiones dentro de la industria de producción de estructuras de acero. El cálculo de costes por procesos permite tomar decisiones estratégicas y garantiza la rentabilidad y sostenibilidad generales del proceso de producción de estructuras de acero. Objetivo. Explicar la importancia de la contabilidad de costos en la producción de estructuras de acero. Metodología. La metodología de investigación propuesta para el estudio está compuesta de los siguientes pasos: a. Planteamiento del problema. b. Revisión de literatura. c. Diseño de investigación. d. Recopilación y análisis de datos. e. Resultados y conclusiones. f. Bibliografía. g. Redacción del artículo. Cada uno de ellos bien definidos. Resultados. Se obtienen los siguientes resultados en diferentes componentes. 1. Componentes de coste en la producción de estructuras de acero. 2. Métodos de imputación de costes en la producción de estructuras de acero. 3. Técnicas de estimación de costes para la producción de estructuras de acero. 4. Medidas de control de costes en la producción de estructuras de acero. 5. Procesos de producción de estructuras de acero. 6.Control de calidad en la producción de estructuras de acero. 7. Retos de la contabilidad de costes en la producción de estructuras de acero. 8. Casos prácticos y mejores prácticas de contabilidad de costes en la producción de estructuras de acero. Conclusión. La contabilidad de costes desempeña un papel crucial en la producción de estructuras de acero, los costes que se debe considerar son: los costes de material, los costes de mano de obra y los gastos generales, las empresas pueden tomar decisiones con conocimiento de causa y controlar eficazmente los costes. Existen diversos métodos de imputación de costes, como la imputación de costes directos e indirectos y el cálculo de costes por actividades, ayudan a asignar los costes con precisión a los distintos procesos de producción. Finalmente, la contabilidad de costes es una herramienta vital para optimizar los procesos de producción y garantizar la rentabilidad y sostenibilidad de la producción de estructuras de acero.
Mikrozonasi Seismik : Sebuah Pendekatan Delineasi Penguatan Gelombang Seismik oleh Sedimen Permukaan untuk Penyediaan Data Dasar Penataan Ruang Wilayah, Studi Kasus Daerah Demak, Jawa Tengah
Authors: Marjiyono  , J.H Setiawan , Hidayat  , S Andriani , A Ibrahim , W.T Buana , Subagio  
Published: August 2023

Kerusakan bangunan dan infrastruktur dalam kejadian gempabumi tidak hanya terkait dengan besaran gempabumi dan jarak sumbernya, tetapi juga sangat dipengaruhi oleh kondisi geologi permukaan. Daerah dengan litologi permukaan yang belum mengalami konsolidasi cenderung menguatkan gelombang yang meningkatkan intensitas goncangan. Karakterisasi sedimen permukaan diperlukan dalam rangka mengidentifikasi nilai panguatan gelombang. Sebagai daerah yang telah ditetapkan menjadi Kawasan Strategis Nasional, ketersediaan data mikrozonasi seismik di daerah Demak dan sekitarnya untuk penataan ruang wilayah mutlak diperlukan. Pengukuran mikrotremor array dan single station telah dilakukan untuk memodelkan kondisi bawah permukaan dangkal. Hasil analisis nilai penguatan gelombang menunjukkan zona kerentanan tinggi menempati bagian tengah, timur dan utara daerah penyelidikan. Zona kerentanan tinggi direkomendasikan untuk pengembangan sektor-sektor beresiko rendah. Pengembangan perkotaan lebih lanjut direkomendasikan di zona kerentanan rendah.

Kata kunci : tata ruang wilayah, penguatan gelombang, mikrozonasi seismik, mikrotremor, kerentanan.
Do visual and step height factors cause imbalance during bipedal and unipedal stances? A plantar pressure perspective
Authors: Guo Panjing , Wang Duoduo , Li Yumin , Wang Ruiqin , Xu Haoran , Han Jia , Lyu Jie 
Published: August 2023

Objective: The plantar pressure analysis technique was used to explore the static balance ability and stability of healthy adult males under the influence of visual and step height factors during bipedal and unipedal stances.Methods: Thirty healthy adult males volunteered for the study. Experiments used the F-scan plantar pressure analysis insoles to carry out with eyes open (EO) and eyes closed (EC) at four different step heights. The plantar pressure data were recorded for 10 s and pre-processed to derive kinematic and dynamic parameters.Results: For unipedal stance, most of kinematic parameters of the subjects’ right and left feet were significantly greater when the eyes were closed compared to the EO condition and increased with step height. The differences in toe load between right and left feet, open and closed eyes were extremely statistically significant (p &lt; 0.001). The differences in midfoot load between the EO and EC conditions were statistically significant (p = 0.024) and extremely statistically significant between the right and left feet (p &lt; 0.001). The difference in rearfoot load between EO and EC conditions was extremely statistically significant (p &lt; 0.001) and statistically significant (p = 0.002) between the right and left feet. For bipedal stance, most of kinematic parameters of the subjects’ EO and EC conditions were statistically significant between the right and left feet and increased with step height. The overall load’s difference between EO and EC states was statistically significant (p = 0.003) for both feet. The overall load’s difference between the right and left feet was extremely statistically significant (p &lt; 0.001) in the EC state. The differences between the right and left feet of the forefoot and rearfoot load with EO and EC suggested that the right foot had a smaller forefoot load, but a larger rearfoot load than the left foot (p &lt; 0.001). The differences between the forefoot and rearfoot load of the subjects’ both feet with EO and EC were extremely statistically significant (p &lt; 0.001).Conclusion: Both visual input and step height factors, even the dominant foot, act on kinematic and dynamic parameters that affect the maintenance of static balance ability.
Explainable AI: roles and stakeholders, desirements and challenges
Authors: Hoffman Robert R. , Mueller Shane T. , Klein Gary , Jalaeian Mohammadreza , Tate Connor 
Published: August 2023

IntroductionThe purpose of the Stakeholder Playbook is to enable the developers of explainable AI systems to take into account the different ways in which different stakeholders or role-holders need to “look inside” the AI/XAI systems.MethodWe conducted structured cognitive interviews with senior and mid-career professionals who had direct experience either developing or using AI and/or autonomous systems.ResultsThe results show that role-holders need access to others (e.g., trusted engineers and trusted vendors) for them to be able to develop satisfying mental models of AI systems. They need to know how it fails and misleads as much as they need to know how it works. Some stakeholders need to develop an understanding that enables them to explain the AI to someone else and not just satisfy their own sense-making requirements. Only about half of our interviewees said they always wanted explanations or even needed better explanations than the ones that were provided. Based on our empirical evidence, we created a “Playbook” that lists explanation desires, explanation challenges, and explanation cautions for a variety of stakeholder groups and roles.DiscussionThis and other findings seem surprising, if not paradoxical, but they can be resolved by acknowledging that different role-holders have differing skill sets and have different sense-making desires. Individuals often serve in multiple roles and, therefore, can have different immediate goals. The goal of the Playbook is to help XAI developers by guiding the development process and creating explanations that support the different roles.
Assessment of dysfunctional tunneled hemodialysis catheters and outcome of endovascular salvage techniques: a simple solution to a complex problem
Authors: Xu Tao , Zeng Ni , Li Nan 
Published: August 2023

ObjectiveThe aim of this study was to evaluate the causes of the dysfunctional tunneled cuffed catheters (TCCs) using multi-spiral computed tomography venography (MSCTV), and to analyze the outcomes of endovascular salvage techniques.Material and methodsThis retrospective review data from 27 patients who experienced TCC dysfunction between July 1, 2016 and January 31, 2021 was conducted. Patients’ demographic data, clinical signs and symptoms, and imaging data were collected from interventional radiology database.ResultsMSCTV showed a range of abnormalities in the hemodialysis (HD) patients, including central venous occlusion (n = 4), fibrin sheath formation (n = 3), malposition of the catheter tips (n = 4), central venous perforation (n = 1), thrombus formation (n = 12), regular catheter exchange without determined lesions (n = 3). Interventional catheter salvage procedures were performed, such as catheter exchange, balloon disruption of a fibrin sheath, angioplasty for central vein stenosis, and stent deployment. The technical success rate for catheter insertions was 100%, and no procedure-related severe complications were observed. The 30-day catheter patency for all assessable catheters was 85.2%.ConclusionThe use of MSCTV showed abnormal findings in almost 88.9% of cases concerning dysfunctional TCC. In this study, the examined appropriate endovascular techniques were found to be safe and technically successful, with a low incidence of procedure-related complications.
High-density mapping of the average complex interval helps localizing atrial fibrillation drivers and predicts catheter ablation outcomes
Authors: Squara Fabien , Scarlatti Didier , Bun Sok-Sithikun , Moceri Pamela , Ferrari Emile , Meste Olivier , Zarzoso Vicente 
Published: August 2023

BackgroundPersistent Atrial Fibrillation (PersAF) electrogram-based ablation is complex, and appropriate identification of atrial substrate is critical. Little is known regarding the value of the Average Complex Interval (ACI) feature for PersAF ablation.ObjectiveUsing the evolution of AF complexity by sequentially computing AF dominant frequency (DF) along the ablation procedure, we sought to evaluate the value of ACI for discriminating active drivers (AD) from bystander zones (BZ), for predicting AF termination during ablation, and for predicting AF recurrence during follow-up.MethodsWe included PersAF patients undergoing radiofrequency catheter ablation by pulmonary vein isolation and ablation of atrial substrate identified by Spatiotemporal Dispersion or Complex Fractionated Atrial Electrograms (&gt;70% of recording). Operators were blinded to ACI measurement which was sought for each documented atrial substrate area. AF DF was measured by Independent Component Analysis on 1-minute 12-lead ECGs at baseline and after ablation of each atrial zone. AD were differentiated from BZ either by a significant decrease in DF (&gt;10%), or by AF termination. Arrhythmia recurrence was monitored during follow-up.ResultsWe analyzed 159 atrial areas (129 treated by radiofrequency during AF) in 29 patients. ACI was shorter in AD than BZ (76.4 ± 13.6 vs. 86.6 ± 20.3 ms; p = 0.0055), and mean ACI of all substrate zones was shorter in patients for whom radiofrequency failed to terminate AF [71.3 (67.5–77.8) vs. 82.4 (74.4–98.5) ms; p = 0.0126]. ACI predicted AD [AUC 0.728 (0.629–0.826)]. An ACI &lt; 70 ms was specific for predicting AD (Sp 0.831, Se 0.526), whereas areas with an ACI &gt; 100 ms had almost no chances of being active in AF maintenance. AF recurrence was associated with more ACI zones with identical shortest value [3.5 (3–4) vs. 1 (0–1) zones; p = 0.021]. In multivariate analysis, ACI &lt; 70 ms predicted AD [OR = 4.02 (1.49–10.84), p = 0.006] and mean ACI &gt; 75 ms predicted AF termination [OR = 9.94 (1.14–86.7), p = 0.038].ConclusionACI helps in identifying AF drivers, and is correlated with AF termination and AF recurrence during follow-up. It can help in establishing an ablation plan, by prioritizing ablation from the shortest to the longest ACI zone.