bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Decomposition approach for Assessing Land Leverage and Depreciation Rate on the Real Estate Market – Evidence from Warsaw Poland
Authors: Waszczuk Joanna 
Published: March 2023

ABSTRACT
Most property valuation research concerns entire properties consisting of land and structures. However, different features of land and capital as factors of production determine different patterns shaping their value and their different impact on the total price of real estate. In this article the hedonic decomposition model, which controls for differences in housing quality, is applied to decompose the price of an apartment into the land and structure components. The depreciation rate of housing was calculated and taken into account to properly isolate the dynamics of land over time. This allowed us to compare the house price index with the dynamics of land and structure. The empirical analysis was carried out on the data for the city of Warsaw.
Points of Interest and Housing Prices
Authors: Cellmer Radosław 
Published: March 2023

ABSTRACT
Points of Interest (POI) are an inherent element of the urban landscape, and their number and density reflect, among other things, the degree of urbanization and the city’s spatial structure. The very presence of POI in the closest vicinity of a residential property may indirectly or directly affect housing value. This paper aims to demonstrate the usefulness of POI density information of different categories in assessing the quality of a property’s immediate surroundings. While the mere presence of POIs in the nearest neighborhood may affect real estate prices, the influence of specific categories may not necessarily be positive. Therefore, the study attempted to classify POIs and determine their importance in the price formation process using spatial regression models. The results indicate that a high density of POIs in the immediate area is a stimulant for housing prices. The detailed analysis indicated that only some POI categories might be related to transaction prices, while in certain situations, some POI categories may negatively impact prices.
Photocatalytic Properties of Co-precipitated Bismuth Cobalt Ferrite
Authors: Catur Saputri Abi , Prasetya Nurdiyantoro Putra , Utari Utari , Purnama Budi 
Published: March 2023

Bismuth substituted cobalt ferrite nanoparticle is studied for photocatalytic in this paper. Bismuth cobalt ferrite has been synthesized by the coprecipitation method and low-temperature annealing treatment. The characterization results showed that the XRD spectral pattern is consistent with ICDD 221086. The crystallite size of bismuth cobalt ferrite increases with increasing annealing temperature. FTIR results confirm the available metal-oxide at number wave around 570/cm and 475/cm which is the appearance of octahedral and tetrahedral sites owing cobalt ferrite. The photocatalyst test was carried out by varying the catalyst mass and UV irradiation time. The absorption spectrum decreases with increasing catalyst mass. The increase in UV irradiation time causes the formation of more holes (h+) and electrons (e-). So that the hydroxide reaction occurs that produces free radicals. The results of this study indicate that cobalt ferrite-based nanoparticles have potential as photocatalyst materials.
Efficacy and Safety of Tralokinumab in US Adults with Moderate-to-Severe Atopic Dermatitis: A Post-hoc Analysis of ECZTRA3
Authors: Elewski Boni , Zirwas Matthew , Kurbasic Azra , Schneider Shannon , Claxton Ami , Silverberg Jonathan 
Published: March 2023

Background: Tralokinumab, a monoclonal antibody that specifically neutralizes interleukin (IL)-13, is approved for the treatment of adults with moderate-to-severe atopic dermatitis (AD). Tralokinumab was studied in ECZTRA3 (NCT03363854), a randomized, double-blind, multi-national, placebo-controlled Phase 3 trial of tralokinumab in adults with moderate-to-severe AD.
Objective: We conducted a post-hoc analysis in the United States (US) subset of ECZTRA3 patients to inform healthcare practitioners and payers on the efficacy and safety of tralokinumab in the US setting.
Methods: Patients were treated with either 300 mg tralokinumab (n=63) or placebo (n=25) every 2 weeks (Q2W) in combination with TCS as needed for an initial 16 weeks. Thereafter, tralokinumab-treated patients continued with either Q2W dosing or Q4W+TCS for 16 additional weeks. Primary, secondary, and safety endpoints of the ECZTRA3 US subset were evaluated at 16 and 32 weeks following main statistical analyses (previously published).
Results: At Week 16, 37.1% tralokinumab+TCS vs 12.0% placebo+TCS reached Investigator’s Global Assessment (IGA) 0/1 (nominal P=0.039); 56.5% of tralokinumab+TCS vs 24.0% placebo+TCS (nominal P=0.012) achieved the Eczema Area and Severity Index (EASI)-75. Secondary, patient-reported outcomes including itch score and health-related quality of life (HRQoL) were also improved at Week 16 versus baseline, more so for tralokinumab+TCS group. Tralokinumab was well tolerated, with an overall safety profile comparable to placebo.
Conclusions: Consistent with the full ECZTRA3 population, US patients with moderate-to-severe AD treated with tralokinumab+TCS as needed achieved greater symptom relief, reductions in disease severity and improvement of HRQoL than placebo+TCS, with comparable safety.
Investigator global assessment (IGA) of Acne Vulgaris and IGA Success among patients with moderate to severe non-nodular Acne Vulgaris (AV) administered sarecycline in community practices across the U.S: PROSES study analysis by gender and age
Authors: Graber Emmy , Baldwin Hilary , Harper Julie , Stein Gold Linda , Alexis Andrew , Fried Richard , Rieder Evan , Del Rosso James , Kircik Leon , Narayanan Siva , Koscielny Volker , Kasujee Ismail , Hebert Adelaide 
Published: March 2023

Introduction: The objective of this analysis was to evaluate facial IGA and the associated IGA success, stratified by age and gender, among AV patients administered sarecycline in community practices across the U.S.
Methods: A single-arm, prospective cohort study (PROSES) was conducted with moderate-to-severe non-nodular AV patients >9 years who were prescribed sarecycline in real-world community practices in the US. Facial IGA of AV status was collected on a five-point adjectival response scale (0(clear)-4(severe)). IGA success at week-12 was defined as >2-grade improvement and score 0-clear or 1-almost clear at week-12. Proportion of patients achieving IGA success was analyzed, stratified by gender and age (9-17yrs, >=18yrs).
Results: A total of 253 AV patients completed the study (female: 66.40%; 9-17yrs: 39.92%; >=18yrs: 60.08%; Facial IGA success at week-12 was 56.47% for male and 60.12% for female; 57.43% for patients 9-17yrs old and 59.87% for patients >=18yrs old.
Conclusion: Within the study cohort of adolescent and adult patients with moderate to severe AV at baseline administered sarecycline, a narrow-spectrum, tetracycline-derived antibiotic for 12 weeks, across the gender and age groups, majority of patients achieved IGA success at week-12.
Intralesional Treatment of Basal Cell Carcinoma in a Genetically Inducible Mouse Model
Authors: Messier Nancy , Couture Frédéric , Théberge Vanessa , Harvey Mario , Kobayashi Kenneth 
Published: March 2023

Introduction: Patients with nevoid basal cell carcinoma syndrome (NBCCS), also termed Gorlin syndrome, develop numerous basal cell carcinomas (BCCs). Current treatment options include systemic hedgehog pathway inhibitors, with significant side effects when used long term, and multiple surgeries with the risk of scarring and sometimes even disfigurement over the long term. We have developed an intralesional treatment for BCC based on the intracellular delivery of an antisense oligonucleotide (ASO) targeting Gli1, the main protein active in the hedgehog pathway responsible for BCC. To test the efficacy of our treatment, we developed an inducible NBCCS-like mouse model, genetically modified at the level of the expression of the Ptch1 and p53 genes in the skin.
Methods: The inducible mouse model uses Ptch1- and P53-knockdown mice irradiated with UVB three times a week until BCCs appear. These BCCs were treated once or twice a week with injections of an antisense oligonucleotide (ASO) targeting the production of the Gli1 protein, with and without the use of a peptide (the “Feldan shuttle") designed to introduce the ASO into the tumor cells. The evolution of the tumors was monitored several times a week with caliper measurements and photography. Following the treatments, the tumor site tissue was harvested and analyzed by both routine (H&E) and specialized (IHC, IF) histologic methods .
Results: Intralesional treatment of BCCs in the inducible mouse model using the ASO and peptide combination (FLD103) resulted in rapid and marked tumor regression, and sometimes complete eradication, over a few weeks. In addition, healthy perilesional skin appeared unaffected by the treatment, demonstrating targeted treatment specificity. The healed skin appeared grossly normal. Histologic examination of the treated sites after recovery showed no residual BCC as well as complete healing of the epidermis, dermis and subcutaneous tissue. We also observed that intralesional treatment with the ASO alone is not associated with tumor regression and in fact permits continued tumor growth.
Conclusion: We have demonstrated the utility of a specific intralesional treatment for BCC in a genetically inducible mouse model. This alternative and novel treatment produces rapid results with normal healing of the treated site. This treatment could offer an attractive option for patients with multiple BCCs who wish to avoid systemic treatments or multiple surgeries.
MODELS OF THERMOELASTICITY FOR POROUS MATERIALS WITH FRACTURES TAKEN INTO ACCOUNT
Authors: Алексеев В.Н. , Васильева М.В. , Прокопьев Г.А. , Тырылгин А.А. 
Published: March 2023

Предложена математическая модель и вычислительный алгоритм для решения задач термоупругости в трещиноватых пористых средах. Для моделирования теплопереноса в пористых средах строится математическая модель с использованием моделей двойной диффузии. Учет теплопереноса в трещинах проводится посредством задания интерфейсного условия, позволяющего моделировать скачок температуры на границе трещин. Для расчета напряженно-деформированного состояния используется модель линейной упругости с дополнительным условием на трещине. Для численного решения задачи строится аппроксимация с использованием разрывного метода Галеркина, позволяющего учитывать интерфейсное условие в вариационной постановке. Приводятся результаты численного решения модельной задачи с использованием предложенной модели термоупругости.
We propose a mathematical model and a computational algorithm for solving thermoelasticity problems in fractured porous media. To simulate heat transfer in porous media, a mathematical model is constructed using double diffusion models. The heat transfer in the cracks is taken into account by setting the interface condition which allows modeling the temperature jump at the crack boundary. To calculate the stress-strain state, a linear elasticity model is used with an additional condition on the crack. For the numerical solution of the problem an approximation is constructed using the Galerkin discontinuous method which allows taking into account the interface condition in the variational formulation. We present the results of the numerical realization of the model problem using the proposed model of thermoelasticity.
An optimal size of an external rigid thin inclusion for a nonlinear problem describing equilibrium of a three-dimensional cracked cylindrical body
Authors: Лазарев Н.П. , Эверстов В.В. 
Published: March 2023

Изучена математическая модель о равновесии упругого цилиндрического тела с трещиной, скрепленного на внешней границе жестким тонким включением. На поверхности, задающей трещину, ставится условие непроникания в виде неравенства. Проводится анализ зависимости решений от параметра, характеризующего размер тонких жестких включений. Доказано существование решения задачи оптимального управления. Для этой задачи функционал качества определен с помощью произвольного функционала, непрерывного в пространстве решений. Параметр управления задается размером жестких тонких включений.
A mathematical model describing equilibrium of cracked three-dimensional bodies with rigid thin stiffener on the outer boundary is studied. Inequality type boundary condition is imposed at the crack faces providing a mutual non-penetration between crack faces. We analyze the dependence of solutions on the size of the thin rigid stiffener reinforcing the cracked body on the outer edge. Existence of the solution to the optimal control problem is proved. For this problem the cost functional is defined by an arbitrary continuous functional, while the size parameter of the thin rigid stiffener is chosen as a control parameter.
Initial-boundary problem with conjugation conditions for composite-type equations with two breakdown coefficients
Authors: Григорьева А.И. 
Published: March 2023

Изучается разрешимость начально-краевой задачи с условиями сопряжения для двух неклассических дифференциальных уравнений составного типа. Описывается случай, когда коэффициенты каждого рассматриваемого уравнения имеют разрыв 1-го рода в точке нуль. Область исследований задана в виде полосы ввиду наличия точки разрыва, состоящей из двух подобластей. Таким образом, исследуемые уравнения рассматриваются в двух различных областях. Для доказательства существования и единственности регулярных решений (которые имеют все обобщенные производные, входящие в уравнения) начально-краевой задачи используется метод продолжения по параметру, имеющий широкое применение в теории краевых задач. С помощью принципа максимума устанавливается наличие всех необходимых априорных оценок для решений изучаемой задачи.
In this paper we study the solvability of an initial-boundary value problem with conjugation conditions for two nonclassical differential equations of composite type. We describe the case when the coefficients of each equation under consideration have a discontinuity of the first kind at the point zero. The field of research is given in the form of a band, due to the presence of a discontinuity point consisting of two subregions. Thus, the investigated equations are considered in two different areas. To prove the existence and uniqueness of regular solutions (which have all the generalized derivatives entering into the equations) of the initial-boundary value problem, we use the method of continuation with respect to a parameter, which has a wide application in the theory of boundary value problems. Using the maximum principle, the presence of all necessary a priori estimates for the solutions of the problem being studied is established.
ON DIMENSION OF THE SPACE OF KILLING FIELDS ON k–SYMMETRIC LORENTZIAN MANIFOLDS
Authors: Оскорбин Д.Н. , Родионов Е.Д. , Эрнст И.В. 
Published: March 2023

Исследованы поля Киллинга на kсимметрических лоренцевых многообразиях. Множество решений уравнения Киллинга образуют алгебру Ли киллинговых полей. Представленное исследование сфокусировано прежде всего на размерности этой алгебры. Рассмотренные лоренцевы многообразия, называемые обобщенными пространствами Кахена Уоллаха, имеют удобную систему локальных координат. В локальных координатах описано общее решение уравнения Киллинга на локально неразложимых 2симметрических лоренцевых многообразиях, которые являются обобщенными многообразиями Кахена Уоллаха, что было показано А. С. Галаевым и Д. В. Алексеевским. Дано явное описание всех возможных размерностей алгебры киллинговых полей на 2симметрических лоренцевых многообразиях малых размерностей.
We study the Killing equation on ksymmetric Lorentzian manifolds. Solutions of this equation form a Lie algebra called the algebra of Killing fields. Our consideration is focused primarily on the dimension of the Lie algebra of Killing fields. The Lorentzian manifolds we consider in this article are the generalized Cahen Wallach spaces, which are convinient to use because of the coordinate system they have. Using these coordinates, we describe the general solution of the Killing equation on locally indecomposable 2symmetric Lorentzian manifolds, which are generalized CahenWallach spaces, as was proved by A. S. Galaev and D. V. Alekseevsky. Finally, we give an explicit description of all possible dimensions of the algebra of Killing fields on 2symmetric Lorentzian manifolds of small dimensions.
PECULIARITIES OF THE DYNAMICS OF A BROWNIAN PARTICLE WITH RANDOM DISTURBANCES ORTHOGONAL TO ITS SPEED
Authors: Дубко В.А. 
Published: March 2023

Классические диффузионные уравнения основаны на предположении, что скорости броуновской частицы могут принимать сколь угодно большие значения. В статье показано, что для решения уравнения Ланжевена, когда случайные влияния ортогональны скорости частицы, может существовать притягивающая поверхность для скорости, несмотря на то, что процесс Винера это процесс, который принимает сколь угодно большие значения. В отличие от наших предыдущих статей и статей других исследователей, в этой статье построено уравнение для определения вероятности распределения частиц в координатном пространстве с учетом зависимости от начального направления скорости. Показано, что при определенном согласовании коэффициентов в исходном стохастическом уравнении небольшие случайные влияния приводят к описанию плотности вероятности положения частицы на основе волновых уравнений. Отмечено, что рассмотренные уравнения не исчерпывают класс моделей, когда возмущения ортогональны компоненте решения. Расширенный класс стохастических уравнений с ортогональными возмущениями рассматривался в предыдущих работах автора, в том числе для nмерных процессов, в связи с развитием теории первых интегралов для стохастических систем.
The classical diffusion equations are based on the assumption that the velocities of a Brownian particle can take arbitrarily large values. In this article, it is shown that for solving the Langevin equations when random influences are orthogonal to the particle velocity there might exist an attractive surface for velocity, despite the fact that the Wiener process is a process that takes arbitrarily large values. Unlike the previous articles, here we construct an equation for determining the probability density of the distribution of particles in the coordinate space taking the initial direction of velocity into account. It is shown that small influences with a certain agreement of the coefficients in the initial stochastic equation lead to a description of the moving particle based on the wave equations with constant speed. The considered equations do not exhaust the class of models when the perturbations are orthogonal to the vector component of the solution. An extended class of stochastic equations with orthogonal perturbations was considered in previous works of the author, in particular, for ndimensional processes, in connection with the development of the theory of first integrals for stochastic systems.
THE ALGORITHM FOR SOLVING THE DIRECT KINEMATIC PROBLEM OF SEISMICS IN THREE–DIMENSIONAL HETEROGENEOUS ISOTROPIC MEDIA
Authors: Галактионова А.А. , Белоносов А.С. 
Published: March 2023

Решение прямой кинематической задачи сейсмики важный этап обработки данных полевых измерений в сейсмологии и сейсморазведке, например, при решении обратной кинематической задачи сейсмики методом нелинейной лучевой сейсмотомографии 1, в методе пространственно-временной миграции Кирхгофа и др. К настоящему моменту существует несколько подходов к решению данной задачи. К наиболее популярным из них относятся: 1) методы, основанные на решении двухточечной краевой задачи 2) метод волновых фронтов 3) разностные методы решения уравнения эйконала и др. 2, 3. Предлагаемый в работе метод относится к методам лучевого трассирования 4 и преодолевает некоторые ограничения, присущие вышеперечисленным методам. Основой подхода, предложенного в данной работе, является итерационный метод Ньютона Канторовича. Алгоритм трехмерной пристрелки прост в реализации и допускает почти линейное распараллеливание. Вопросы сходимости метода Ньютона в применении к поставленной задаче в данной работе не рассматриваются. Также не рассматриваются вопросы применимости метода при наличии каустик, зон тени, дифракции.
The solution of the direct kinematic problem of seismics is an important stage of the seismic data processing in seismology and seismic explorations, e.g., while solving the inverse kinematic problem of seismics by the method of nonlinear seismic tomography, in the method of the space-time Kirchhoffs migration, etc. There are several approaches now to the solution of this problem: 1) methods based on the solution of two-point boundary value problems 2) the wavefront construction method 3) finite-difference methods for solving eikonal differential equations, etc. 23. The method proposed in this paper relates to ray tracing methods and overcomes some of the limitations inherent in the above methods. The basis of the approach is the iterative Newtons method. The algorithm of threedimensional shooting is simple to implement and allows almost linear speedup from parallelization. Questions of convergence of the Newton method applied to this problem are not considered in this paper. In addition, we do not consider the applicability of the method in the presence of caustics, shadow zones, and diffraction.
INTEGRAL TOPOGRAPHIC CHARACTERISTICS IN SOLVING PROBLEMS OF REMOTE SENSING DATA PROCESSING
Authors: Самарина О.В. , Семенов С.П. 
Published: March 2023

Одной из наиболее актуальных задач цифровой обработки изображений является задача поиска новых математических подходов к анализу и обработке многоканальных изображений (в том числе данных дистанционного зондирования Земли). Актуальность этих исследований определена необходимостью оптимизации существующих методов цифровой обработки изображений, повышения эффективности и качества результатов, получаемых в результате анализа цифрового сигнала. В работе предложен подход к обработке данных дистанционного зондирования Земли, основанный на определенных инвариантных интегрально-геометрических характеристиках цифрового изображения. Инвариантные характеристики играют важную роль в обработке цифрового сигнала и широко используются в задачах распознавания образов, при поиске структурных соответствий по образцу, в задачах дистанционного зондирования, геологических исследованиях. В работе также представлено описание программного модуля, разработанного в системе MatLab в целях анализа изображений и вычисления указанных числовых характеристик.
Search for new mathematical approaches to the multichannel images analysis and processing (including Earth remote sensing data) is one of the topical problems in digital image processing. The relevance of it is determined by the need to optimize the existing methods of digital image processing, to improve the efficiency and quality of the results obtained from the digital signal analysis. In this paper, we present an approach to Earth remote sensing data processing based on invariant integral-geometric characteristics of the digital image. The invariant characteristics play an important role in digital signal processing and are widely used in pattern recognition tasks, in pattern structural matching, in remote sensing tasks, and in geological research. The paper also describes a MatLab software module developed for image analyzing and calculating of the numerical integral-geometric characteristics.