bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global reach, regional strength: Spatial patterns of a big science facility
Authors: Söderström Kristofer Rolf 
Published: June 2023

AbstractThe European Synchrotron Radiation Facility (ESRF), a leading facility in synchrotron science, plays a crucial role in supporting both the local and the international scientific community by providing advanced instrumentation for their research. However, our understanding of the actual reach of the facility and its spatial dynamics remains limited. Thus, a methodology is proposed where author affiliation links are processed, analyzed, and visualized. A case study that focuses on the ESRF is implemented, where the author affiliation links of 17,870 publications over the period 2011–2021 are processed, revealing 76,850 addresses, of which 11,120 are unique locations. The results of the case study bring to light robust patterns of increased internationalization over time, accompanied by regional agglomeration and the emergence of potential research hotspots. The methodology and results are likely to be of interest to researchers in Spatial Scientometrics, which addresses some of the current challenges in the field. Managers, funders, and policy‐makers can utilize this method or similar approaches to enrich impact analyses of large‐scale science facilities, vital for insuring their sustained support. The code for the methodology, as well as the interactive visualizations, is freely available on GitHub for further exploration and replication of the methodology.
Fault‐tolerant control of multi‐agent systems with input delay and sensor failure
Authors: Syed Ali Muhammed , Mubeen Tajudeen Muhammed Haneef , Rajchakit Grienggrai , Hammachukiattikul Porpattama , Cao Jinde 
Published: June 2023

AbstractThe problem of fault‐tolerant control (FTC) for a multi‐agent system (MAS) with input delay and sensor failures is addressed in this study. The topology of communication is an undirected subgraph having directed connections between the followers and leader. The Lyapunov approach is used to identify sufficient criteria for consensus control. We propose a fault‐tolerant controller based on observed descriptors. On the basis of proposed fault‐tolerant control, actuator problems, sensor faults, and state estimations can be solved. To minimize the size of the data, the Artstein–Kwon–Pearson reduction method is applied. Based on a Lyapunov functional predictive descriptor observer architecture, sufficient conditions are derived to guarantee the asymptotic stability. To demonstrate the theoretical results, numerical examples are provided.
Anxiety in autistic preschool children: Phenomenology and a network analysis of correlates
Authors: Vasa Roma A. , Kerns Connor M. , Singh Vini , McDonald Rachel , Jang Yeon Sik , Keefer Amy 
Published: June 2023

AbstractAnxiety disorders in autistic children are associated with significant functional impairment. Few studies have examined impairing anxiety presentations in autistic preschool children (i.e., 3–5 years old). This cross‐sectional study examined the phenomenology of impairing anxiety and the strongest correlates of anxiety in 75 autistic preschool children. Parents completed a diagnostic interview that assesses two anxiety types, DSM‐5 anxiety disorders and impairing distinct anxiety presentations, and measures of anxiety correlates. An exploratory network analysis examined connections between anxiety and its correlates. Forty percent of children had impairing anxiety. Specific phobia followed by ‘other social fear,’ a type of distinct anxiety, were the most common anxiety types. Child intolerance of uncertainty (IU) was the only correlate that was associated with anxiety in a network analysis framework. Child IU linked anxiety to two other correlates, sensory over‐responsivity and somatic symptoms. Findings emphasize the need for early intervention for anxiety and further research on its correlates.
Butanol and caproate production by consolidated bioprocessing after adaptive evolution of a fermentative microbial community
Authors: González‐Tenorio Diana , Dudek Karol , Valdez‐Vazquez Idania 
Published: June 2023

AbstractButanol production from cellulose by consolidated bioprocessing may accelerate the commercialization of lignocellulosic biofuels. This study applied adaptive evolution to a natural microbial community consisting of different taxa of fermenters and plant‐degrading bacteria to increase its production of butanol. To this end, the parental microbial community was subjected to the stepwise enrichment of butanol at four initial concentrations in repeated‐batch fermentations using pretreated corn stover as the sole substrate. After the adaptive evolution, the microbial community exposed to the highest concentration of butanol produced 13.8 g L‐1 butanol, which was nine times higher than the parental microbial community. The adapted microbial community also produced the medium‐chain fatty acid caproate (7.5 g L‐1) from the condensation of alcohols (ethanol/butanol) with short‐chain fatty acids at the end of the fermentation. A network analysis revealed that the largest subcommunities were represented by Clostridium sensu stricto 7 and Caproiciproducens, which are associated with the production of alcohols (ethanol/butanol) and medium‐chain fatty acids, respectively. In the smaller subcommunities, Pseudomonas, Sutterella, and Pandoraea became more important after adaptive evolution, suggesting the production of extracellular polymeric substances and cross‐stress protection as mechanisms of protection and adaptation against butanol. This study demonstrated that butanol production by the consolidated bioprocessing of cellulose required solventogenic bacteria, diverse taxa of plant‐degrading bacteria that established unique interactions with the fermenters and, more important, members with mechanisms of protection and tolerance to solvents. © 2023 The Authors. Biofuels, Bioproducts and Biorefining published by Society of Industrial Chemistry and John Wiley & Sons Ltd.
Structural, optical, and luminescence properties of Dy3+‐activated potassium calcium silicate phosphor for white light‐emitting diodes
Authors: Sharma Vibha , Maurya Shreya , Anu  , Prasad Aman , Rao Allam Srinivasa 
Published: June 2023

AbstractA dysprosium (Dy3+)‐activated potassium calcium silicate (K4CaSi3O9) phosphor was prepared using a solid‐state synthesis route. The phosphor had a cubic structure with the space group Pa
as confirmed using X‐ray diffraction (XRD) measurements. Details of surface morphology and elemental composition of the as‐synthesized undoped KCS phosphor was obtained using scanning electron microscopy (SEM) and energy‐dispersive X‐ray (EDX) spectroscopy. The chemical structure as well as the vibrational modes present in the as‐prepared KCS phosphor was analyzed using Fourier transform infrared (FT‐IR) spectroscopy. Diffuse reflectance spectra (DRS) were used to determine the optical bandgap of the phosphors and were found to be in the optical range 3.52–3.71 eV. Photoluminescence (PL) spectra showed intense yellow emission corresponding to the 4F9/2→6H13/2 transition under 350 nm excitation. Commission International de l′Eclairage colour chromaticity coordinates were evaluated using the PL spectral data lie within the white region. Dexter theory and the Inokuti–Hirayama (I–H) model were applied to study the nature of the energy transfer mechanism in the as‐prepared phosphors. The relatively high activation energy of the phosphors was evaluated using temperature‐dependent PL (TDPL) data and confirmed the high thermal stability of the titled phosphor. The abovementioned results indicated that the as‐prepared KCS:Dy3+ phosphor was a promising candidate for n‐UV‐based white light‐emitting diodes.
Cancer inequalities in incidence and mortality in the State of São Paulo, Brazil 2001–17
Authors: Ribeiro Adeylson Guimarães , Ferlay Jacques , Vaccarella Salvatore , Latorre Maria do Rosário Dias de Oliveira , Fregnani José Humberto Tavares Guerreiro , Bray Freddie 
Published: June 2023

AbstractBackgroundCancer disparities exist between and within countries; we sought to compare cancer‐specific incidence and mortality according to area‐level socioeconomic status (SES) in the State of São Paulo, Brazil.MethodsCancer cases diagnosed 2003–2017 in the Barretos region and 2001–2015 in the municipality of São Paulo were obtained from the respective cancer registries. Corresponding cancer deaths were obtained from a Brazilian public government database. Age‐standardized rates for all cancer combined and the six most common cancers were calculated by SES quartiles.ResultsThere were 14,628 cancer cases and 7513 cancer deaths in Barretos, and 472,712 corresponding cases and 194,705 deaths in São Paulo. A clear SES‐cancer gradient was seen in São Paulo, with rates varying from 188.4 to 333.1 in low to high SES areas, respectively. There was a lesser social gradient for mortality, with rates in low to high SES areas ranging from 86.4 to 98.0 in Barretos, and from 99.2 to 100.1 in São Paulo. The magnitude of the incidence rates rose markedly with increasing SES in São Paulo city for colorectal, lung, female breast, and prostate cancer. Conversely, both cervical cancer incidence and mortality rose with lower levels of SES in both regions.ConclusionsA clear SES association was seen for cancers of the prostate, female breast, colorectum, and lung for São Paulo. This study offers a better understanding of the cancer incidence and mortality profile according to SES within a highly populated Brazilian state.
Should I adopt an integrated virtual clinic? A dual‐factor theory perspective
Authors: Shankar Amit , Kumar Aman , Yadav Rambalak , Misra Pooja , Pani Saroj Kumar 
Published: June 2023

AbstractThis study investigates consumers' adoption intention toward the virtual clinic. The theory of planned behavior and status‐quo‐bias theory are used as underpinning theories to investigate the effects of enablers and inhibitors, respectively. Further, the mediating role of perceived values on the relationship between enablers, inhibitors, and adoption intention is also investigated. The study also investigates how mediating effect of perceived values varies at different levels of perceived information privacy concerns. The results of this study reveal that attitude, subjective norm, regret avoidance, inertia, and switching costs significantly influence the adoption intention toward virtual clinics. The study's findings will enrich technology adoption and online health literature, especially emerging literature related to the virtual clinic. The study helps healthcare service providers understand consumers' adoption intention of the virtual clinic.
A Novel Multifunctional Crosslinking PVA/CMCS Hydrogel Containing Cyclic Peptide Actinomycin X2 and PA@Fe with Excellent Antibacterial and Commendable Mechanical Properties
Authors: Chen Fengyun , Javeed Ansar , Zeng Qiuyu , Zhang Quan , Han Bingnan 
Published: June 2023

AbstractBacterial infected environments and resulting bacterial infections have been threatening the human health globally. Due to increased bacterial resistance caused by improper and excessive use of antibiotics, antibacterial biomaterials are being developed as alternatives to antibiotics in some cases. Herein, an advanced multifunctional hydrogel with excellent antibacterial properties, enhanced mechanical properties, biocompatibility and self‐healing performance, was designed through freezing‐thawing method. This hydrogel network is composed of polyvinyl alcohol (PVA), carboxymethyl chitosan (CMCS), protocatechualdehyde (PA), ferric iron (Fe) and an antimicrobial cyclic peptide actinomycin X2 (Ac.X2). The double dynamic bonds among protocatechualdehyde (PA), ferric iron (Fe) and carboxymethyl chitosan containing coordinate bond (catechol‐Fe) as well as dynamic Schiff base bonds and hydrogen bonds endowed the hydrogel with enhanced mechanical properties. Successful formation of hydrogel was confirmed through ATR‐IR and XRD, and structural evaluation through SEM analysis, whereas mechanical properties were tested with electromechanical universal testing machine. The resulting PVA/CMCS/Ac.X2/PA@Fe (PCXPA) hydrogel has favorable biocompatibility and excellent broad‐spectrum antimicrobial activity against both S. aureus (95.3 %) and E. coli (90.2 %) compared with free‐soluble Ac.X2, which exhibited subpar performance against E. coli reported in our previous studies. This work provides a new insight on preparing multifunctional hydrogels containing antimicrobial peptides as antibacterial material.
Cerebral venous sinus thrombosis and skull base osteomyelitis as manifestations of cat‐scratch disease in a pediatric patient: A case report and literature review
Authors: Otufowora Ayodeji , Lee Christine , Mohideen Aneeb , DeSena Grace , Pringle Charlene , Guyer Freddie , Sharma Priya , Baines Torrey , Carr Silvana 
Published: June 2023

Key Clinical MessageCat‐scratch disease (CSD) is caused by Bartonella henselae and usually presents with regional lymphadenopathy. Skull base osteomyelitis and cerebral venous sinus thrombosis are rarely reported, particularly in immunocompetent children. CSD should be considered in the differential diagnosis of any patient with persistent headaches in the setting of cat exposure.
Isolated Hodgkin lymphoma of the intracranial dura: A case report and review of the literature
Authors: Kanagalingam Tharsan , Velker Vikram , Pejhan Shervin , Zhang Qi , Mangel Joy , Young Sympascho 
Published: June 2023

AbstractPrimary dural Hodgkin lymphoma (PDHL) is an extremely rare subset of Hodgkin lymphoma (HL). Its existence is controversial, as Hodgkin lymphoma is not traditionally thought to arise from the central nervous system (CNS) or its meninges and only 0.02% of patients with Hodgkin lymphoma have any CNS involvement. We report a case of a 71‐year‐old Caucasian man who presented with progressive fatigue and sudden onset slurred speech, disorientation, and memory loss. Brain imaging identified a large extra‐axial right frontal mass, and he underwent urgent subtotal resection. Pathology and subsequent workup revealed Stage IAE classical Hodgkin lymphoma of the right frontal dura, with no extra‐cranial disease or leptomeningeal spread detected. The patient was subsequently treated with ABVD chemotherapy (completed 2.5 of 4 planned cycles) and 36 Gy in 20 fractions of consolidative involved‐site radiotherapy (ISRT). He has been followed for 5 years with no clinical or radiological signs of recurrence. This is the second confirmed case of intracranial PDHL reported in the literature, with the longest follow‐up for any case of PDHL.
Perforated marginal ulcer following Whipple procedure: A case report
Authors: Rijal Sabina , Awal Shila , Basukala Sunil , Shah Kunda Bikram 
Published: June 2023

Key Clinical MessageMarginal ulcers are rare complications of pancreatoduodenectomy. Patient can present with varying symptoms such as epigastric discomfort, pain, dysphagia, or can present in emergency department with complications like bleeding and perforation.
“Listen louder”: Counselor trainee understanding of diversity in diagnosis
Authors: Dunson Caputo Laura G. , Storlie Cassandra A. 
Published: June 2023

AbstractUsing grounded theory methodology, authors utilized four online focus groups to explore counselor trainees’ understanding of diversity in a mental health diagnosis course. Four overarching themes, each embodied by two subthemes, emerged from the data. Implications for counselor educators teaching diversity in diagnosis to counselor trainees are provided.
Scalable Synthesis of Pre‐Intercalated Manganese(III/IV) Oxide Nanostructures for Supercapacitor Electrodes: Electrochemical Comparison of Birnessite and Cryptomelane Products
Authors: Jones Daniel R. , Hussein Haytham E. M. , Worsley Eleri A. , Kiani Sajad , Kamlungsua Kittiwat , Fone Thomas M. , Phillips Christopher O. , Deganello Davide 
Published: June 2023

AbstractManganese(III/IV) oxide is a promising pseudocapacitive material for supercapacitor electrodes due to favorable attributes such as its chemical resilience, high earth abundance and low specific cost. Herein, the morphological, compositional and electrochemical characteristics of co‐precipitated manganese(III/IV) oxide products, each described by the general formula NaxKyMnOz, are investigated to establish how these properties are influenced by synthesis conditions. NaxKyMnOz growths in low‐temperature (<100 °C) basic and acidic environments are shown to promote the formation of turbostratic birnessite and cryptomelane phases, respectively, with the latter polymorph containing a relatively low concentration of interstitial Na+ and K+ cations. It is demonstrated that K+ pre‐insertion during synthesis yields lower initial charge‐transfer resistances than equivalent Na+ intercalation, and that this parameter correlates strongly with storage performance. Accordingly, Na‐mediated storage initially delivers inferior specific capacitances and Coulombic efficiencies than K‐based mechanisms, but K+ intercalation/deintercalation causes faster capacitance decay during prolonged galvanostatic cycling. Furthermore, whilst crystallographic phase is shown to have a weaker effect on NaxKyMnOz storage properties than the choice of intercalating guest cations, cryptomelane electrodes are more susceptible to cycling‐induced capacitance and efficiency losses than their birnessite counterparts. In combination, these insights provide an instructive foundation for the optimization of NaxKyMnOz in high‐power storage applications.
Valbenazine isomers and enantiomer determination by chiral normal phase liquid chromatography
Authors: Deshmukh Balasaheb R. , Akshinthala Parameswari , Katari Naresh Kumar , Kowtharapu Leela Prasad , Deshpande Girish K. , Battula Sreenivas Rao , Gundla Rambabu 
Published: June 2023

AbstractA novel, simple, specific, rapid, enantioselective normal phase chiral high‐performance liquid chromatographic method with amylose‐based Chiral Pak IG‐3(250 × 4.6 mM) 3.0 μM column was developed and validated for separation and quantification of isomers and enantiomer of Valbenazine. The mobile phase composed of n‐Heptane, isopropyl alcohol, dichloromethane, ethanol, and diethylamine in the ratio of 70:10:15:5:0.1 (V/V/V/VV) with a gradient flow rate was applied. The injection volume was 10 μl, and detection was carried out using a photodiode array detector at 282 nM. The column compartment was set at 35°C. The resolution between the enantiomer and isomers was found to be more than 2.0. The method was linear over the concentration range of limit of quantitation to 250% for isomers and enantiomers. The method was found to be robust with column temperature. The proposed chiral method is applicable for the determination of isomers and enantiomer of Valibenazine and was successfully used in the quality control of bulk drug manufacturing and pharmaceuticals.
Chloride‐Promoted Photoelectrochemical C—H Silylation of Heteroarenes†
Authors: Zhao Xin‐Ru , Zhang Yu‐Chen , Hou Zhong‐Wei , Wang Lei 
Published: June 2023

Comprehensive SummaryA photoelectrochemical approach for the C—H silylation of heteroarenes through dehydrogenation cross‐coupling with H2 evolution has been developed. The photoelectrochemical C—H silylation depends on hydrogen atom transfer (HAT) from silanes to Cl‐radical generated through the light‐induced homolytic cleavage of Cl2, in which Cl2 was produced by electrochemical oxidation of chloride. A large number of silylated heterocyclic molecules are rapidly constructed in satisfactory yields without relying on oxidants and metal reagents.
Direct admission versus interhospital transfer for revascularisation in non‐ST‐segment elevation myocardial infarction
Authors: van Steenbergen Gijs J. , Demandt Jesse P. A. , Schulz Daniela N. , Tonino Pim A. , Dekker Lukas , Vermeer‐Gerritzen Iris , Wijnbergen Inge F. , Thijssen Eric J. M. , Theunissen Luc J. H. J. , Heijmen Eric P. C. M. , Haest Rutger J. P. , Vlaar Pieter‐Jan , van Veghel Dennis 
Published: June 2023

AbstractBackgroundThe differences in outcomes and process parameters for NSTEMI patients who are directly admitted to an intervention centre and patients who are first admitted to a general centre are largely unknown.HypothesisThere are differences in process indicators, but not for clinical outcomes, for NSTEMI who are directly admitted to an intervention centre and patients who are first admitted to a general centre.MethodsWe aim to compare process indicators, costs and clinical outcomes of non‐ST‐segment elevation myocardial infarction (NSTEMI) patients stratified by center of first presentation and revascularisation strategy. Hospital claim data from patients admitted with a NSTEMI between 2017 and 2019 were used for this study. Included patients were stratified by center of admission (intervention vs. general center) and subdivided by revascularisation strategy (PCI, CABG, or no revascularisation [noRevasc]). The primary outcome was length of hospital stay. Secondary outcomes included: duration between admission and diagnostic angiography and revascularisation, number of intracoronary procedures, clinical outcomes at 30 days (MACE: all‐cause mortality, recurrent myocardial infarction and cardiac readmission) and total costs (accumulation of costs for hospital claims and interhospital ambulance rides).ResultsA total of 9641 NSTEMI events (9167 unique patients) were analyzed of which 5399 patients (56%) were admitted at an intervention center and 4242 patients to a general center. Duration of hospitalization was significantly shorter at direct presentation at an intervention centre for all study groups (5 days [2–11] vs. 7 days [4–12], p < 0.001). For PCI, direct presentation at an intervention center yielded shorter time to diagnostic angiography (1 day [0–2] vs. 1 day [1–2], p < 0.01) and revascularisation (1 day [0–3] vs. 4 days [1–7], p < 0.001) and less intracoronary procedures per patient (2 [1–2] vs. 2 [2–2], p < 0.001). For CABG, time to revascularisation was shorter (8 days [5–12] vs. 10 days [7–14], p < 0.001). Total costs were significantly lower in case of direct presentation in an intervention center for all treatment groups €10.211 (8750–18.192) versus €13.741 (11.588–19.381), p < 0.001) while MACE was similar 11.8% versus 12.4%, p = 0.344).ConclusionNSTEMI patients who were directly presented to an intervention center account for shorter duration of hospitalization, less time to revascularisation, less interhospital transfers, less intracoronary procedures and lower costs compared to patients who present at a general center.