bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of clinical factors with socio-occupational functioning among individuals with schizophrenia
Authors: Kumari Sunita , Dahuja Shrishti , Singh Upendra 
Published: December 2022

ABSTRACT

Background:
Schizophrenia is assumed to be developing into a marked disability affecting performances in educational and vocational fields for both males and females. It is a psychiatric disorder that has been proven to be associated with poor occupational skills and functioning. This research aimed at studying the clinical correlates of socio-occupational functioning skills of persons with schizophrenia as per the ICD-10, DCR criteria.

Materials and Methods:
The is a cross-sectional descriptive study that included 200 participants diagnosed with schizophrenia, in which sociode mographic and clinical data sheet and Socio-occupational Functioning Scale (SOFS) by Saraswat et al. were used.

Results:
Mean age of the participants was 34 years, with onset of illness being 24 years of age. The results indicated significant correlation at 0.05 level between the total score of SOFS and age of onset and duration of illness.

Conclusion:
It can be concluded that for a better treatment outcome in a disorder like schizophrenia, bio-psychosocial model of treatment is necessary.
A study on the pathogenic microbes and antibiotic-sensitivity patterns in urinary tract infection among diabetes patients at a tertiary care hospital in Central Kerala
Authors: Goswami Tribeni , Krishnamurthy Mathew Samuel , Varghese Sangeetha Merrin 
Published: December 2022

Background:
Diabetes mellitus (DM) has become a global disease that is affecting millions of people, and currently, India has about 50 million patients. Urinary tract infections (UTIs) have long been recognized as a significant problem in patients with DM. This study aimed to find out the pathogenic microorganisms and antibiotic sensitivity patterns for UTI in diabetes patients.

Methodology:
This was a cross-sectional study conducted in the Department of Microbiology at a tertiary care hospital. The duration of the study was for 10 months. Diabetic status was confirmed as per the recommended diagnostic criteria. The identification of the bacterial isolates and antimicrobial sensitivity was carried out by conventional or Vitek-2 compact system. Data were entered in Microsoft Excel and were analyzed using the SPSS version 20. Variables were represented by the frequency and percentage analysis.

Results:
There were 59 positive urine cultures in diabetes patients from January 2021 to October 2021, and the highest number of patients belong to the >70 years' age group. Escherichia coli was the predominant organism isolated and was most sensitive to carbapenems.

Conclusions:
In our study, the elderly female population were found to be the most vulnerable group. The highest sensitivity was observed in carbapenem which can be used for empirical treatment in admitted patients.
Comparison of sublingual misoprostol with intramuscular oxytocin in active management of the third stage of labor
Authors: Charaya Harsha , Soni Monica , Gupta Jeevika , Nayak Asmita 
Published: December 2022

Background:
Postpartum hemorrhage (PPH) is the most common cause of maternal mortality worldwide. Significant numbers are preventable, especially in low-resource settings. Active management of the third stage of labor (AMTSL) is a key denominator. The present study aimed to compare sublingual misoprostol with intramuscular oxytocin in AMTSL to search for an easy and effective alternative for low-resource settings.

Materials and Methods:
A prospective randomized comparative study was conducted, where the subjects were registered over 1 year extending from May 2020 to June 2021 including 200 patients admitted to the labor room with term pregnancy with a period of gestation between 37 and 42 weeks and were divided into two groups, Group A and Group B receiving intramuscular oxytocin and sublingual misoprostol, respectively.

Results:
Sublingual misoprostol was equally effective compared with intramuscular oxytocin in the prevention of PPH. There were no statistical differences in the duration of the third stage of labor, need for additional uterotonics, need for manual removal of placenta, and need for blood transfusion in the two groups.

Conclusion:
Sublingual misoprostol appeared to be as effective as intramuscular oxytocin in the AMTSL and may be an alternative, especially in low-resource settings.
Assessment of breeding sites and seroprevalence of dengue in an urban area of Puducherry – A community-based study
Authors: Velavan A , Shashikala  , Anitha Patricia , Stalin P. , Kumar R. Arun , Purty Anil J. 
Published: December 2022

Background:
Dengue virus infection is an important global public health issue. India is one of the high-burden countries with the resurgence of dengue in recent years. Surveillance based on hospital data can be misleading. Seroprevalence studies in the community are extremely useful in measuring the extent of transmission. This community-based study was done to identify the breeding sites of the Aedes mosquito and measure the seroprevalence of dengue infection in an urban area of Puducherry.

Methodology:
A cross-sectional study was done for 6 months in an urban area of Puducherry to assess the breeding sites for dengue and to find the serological prevalence of dengue. House-to-house visits were done in the study area to collect details on sociodemographic data, environmental data, and breeding sites for dengue. Blood samples were obtained from all willing participants aged 9 years and above to detect specific immunoglobulin G antibodies to dengue virus by enzyme-linked immunosorbent assay.

Results:
The seroprevalence of dengue infection was found to be 8.3%. Flower vase with water 72 (18%), animal water container 32 (8%), roof gutter/sunshades, 25 (6.3%), and open water storage tanks 18 (4.5%) were the most commonly prevalent breeding sites in the study area. The houses with potential breeding sites, such as roof gutters and sunshades, were significantly associated with the prevalence of dengue seropositivity among the study participants.

Conclusion:
The seroprevalence was found to be relatively low in the study area and the potential breeding sites for dengue were identified.
Coronary artery calcification
Authors: Shabestari Abbas Arjmand , Mahdavi Arash , Abrishami Alireza , Alahyari Sam , Molla Mahdieh 
Published: December 2022

Background:
The aim of this study was to evaluate the effect of coronary artery calcification on disease severity and prognosis in patients with coronavirus disease-2019 (COVID-19).

Materials and Methods:
One hundred and forty-one patients with COVID-19 were included in this study. The severity of pulmonary involvement and calcification of coronary arteries were assessed by computed tomography scan and calcification was classified by two methods: Weston and segmental. In both the methods, patients were divided into three groups with scores of 0, 1–6, and 7–12, which are called groups 1, 2, and 3, respectively.

Results:
The mean age of patients was 54.26 ± 14.55. Difference in score of pulmonary involvement was reported to be significant between deceased and discharged patients (11.73 ± 5.26 and 7.28 ± 4.47, P = 0.002, respectively). In Weston score system, the chance of recovery of Group 1 patients was significantly higher than Group 3 (odds ratio [OR] =6.72, P = 0.05, 95% confidence interval [CI] =1.901–50.257). Similar results were observed in the segmental scoring system (OR =6.34, P = 0.049, 95% CI =1.814–49.416). Despite the higher chance of severe disease in patients with coronary artery calcification, this increase was not statistically significant in either Weston or segmental methods (OR =0.47, P = 0.23 and OR =0.85, P = 0.79, respectively).

Conclusion:
Coronary artery calcification in patients with COVID-19 has a significant association with poor prognosis. However, no significant relationship was observed between this issue and the severity.
Economic impact of acute respiratory disease pandemics
Authors: Hadian Shirin Alsadat , Rezayatmand Reza 
Published: December 2022

Background:
The economic impact of acute respiratory disease pandemics has yet to be specifically systematically reviewed. The aim of this scoping review is to identify and classify the economic impacts and its values and ranges.

Materials and Methods:
We conducted a literature search across three key databases using an extensive list of keywords. Then, we included studies which explored direct and indirect costs as well as broader economic impact associated with different nine acute respiratory diseases, i.e., pandemic and seasonal influenza, avian influenza, equine influenza, swine influenza, severe acute respiratory syndrome, coronavirus disease 2019, Middle East respiratory syndrome, H1N1, and H7N9.

Results:
We included 62 studies in English language between 1987 and 2020, mostly from the countries of East Asia and Pacific pertinent. We classified the economic impact into 5 main categories and 18 subcategories. The main categories were macroeconomic impacts, impacts on health cost, industry, businesses and trade, and education.

Conclusion:
Respiratory disease pandemics have widely impacted different sectors of economy such as the direct cost on macroeconomic, providing and receiving health services, disease management, industries, business and trade, education, and indirect costs due to productivity losses. However, lots of the reviewed studies were unable to quantify the actual economic cost of these impacts. This made it challenging to conduct any kind of quantitative comparison of the results. A key priority for future research is to develop standard methods to quantify the broader economic costs of respiratory disease pandemics. Understanding the total economic impact of respiratory disease pandemics is a key step to inform national and international priority setting for disease prevention and pandemic control interventions.
Growth Inhibitory Activity of Brassica oleracea var. Alboglabra on Human Gastric Cancer Cells
Authors: Ngo Dai-Hung , Nguyen Hoang Nhat Minh , Nguyen Thi Nhat Hang , Nguyen Thi Lien Thuong , Ngo Dai-Nghiep , Vo Thanh Sang 
Published: December 2022

Objectives:
The aim of this study is to investigate anticancer activity of Brassica oleracea var. alboglabra (BOA) against the proliferation of BGC-823 human gastric cancer cells.

Materials and Methods:

B. oleracea var. alboglabra was extracted by ethanol 98% at a solid-to-liquid ratio of 1:8, (w/v) for 24h at room temperature. The cytotoxic effect of vegetables was examined by MTT assay. The migration of the cancer cells was conducted by wound healing assay and visualized under an inverted microscope. The mRNA expression level was quantified by real time PCR.

Major Findings:
It was found that ethanol extract of BOA exhibited the inhibitory activity against the proliferation of BGC-823 cells at IC50 value of 217.6 ± 2.8 µg/ml. Moreover, the treatment of BOA extract at concentration of 100 µg/ml for 24 h significantly suppressed the migration of gastric cancer cells into the gap as compared to the untreated cell group. Notably, the cytotoxic effect of BOA extract on human gastric cancer cells was found due to induction of apoptosis, mediating the up-regulation of caspase-8, -9, -3, and Bax in cancer cells.

Conclusion:
These results indicated that B. oleracea var. alboglabra have the potential inhibitory activity against the development of gastric cancer.
Alleviation of Hepatotoxicity by Natural Chelators in Lead-induced Poisoning in Rats
Authors: Nausheen Quadri Neha , Ali Syed A. 
Published: December 2022

Aims:
The study intends to monitor the consequences of lead on the body, its reversal by natural chelators (chitosan and chitosamine), and comparison of monotherapy with the combination using the synthetic ones.

Materials and Methods:
A total of 42 albino Wistar male rats (200–250 g) were divided into seven groups (n = 6). Except for the first group which received sodium acetate 1 g/L (drinking water, vehicle control), all groups received lead acetate 0.4 mg/kg body weight peroral (p.o.). Group II (toxic) received merely lead acetate, whereas the third and fourth groups received 0.2 g/kg (p.o.) of chitosan and chitosamine, respectively. Groups V–VII received ethylenediaminetetraacetic acid (EDTA) 495 mg/kg (p.o.). In addition, the sixth and seventh groups received chitosan and chitosamine (0.2 g/kg) (p.o.), respectively. The hematological, biochemical, oxidative stress parameters, number of porphobilinogen molecules formed/h/mL, and histopathology were assessed. The data obtained were compared using analysis of variance following Tukey’s test.

Results:
The results revealed a statistically significant reduction in the hemogram parameters, antioxidant enzymes, porphobilinogen molecules and an increase in oxidative stress, liver biomarkers along with malondialdehyde in the toxic group in comparison with control and treatment groups. The histopathological findings revealed a significant improvement in the chitosan and chitosamine treatment groups when compared with the toxic group, whereas the results obtained from combination therapy with respect to its monotherapy were most significant than the monotherapy alone.

Conclusion:
Chitosan and chitosamine are found to improve hemato- and hepatotoxicity by chelation and can be used as potent detoxifiers in heavy metal toxicities.
A low peripheral perfusion index can accurately detect prolonged capillary refill time during general anesthesia
Authors: Iizuka Yusuke , Yoshinaga Koichi , Nakatomi Takeshi , Takahashi Kyosuke , Yoshida Kyoko , Sanui Masamitsu 
Published: December 2022

Background:
Capillary refill time (CRT) is the gold standard for evaluating peripheral organ perfusion; however, intraoperative CRT measurement is rarely used because it cannot be conducted continuously, and it is difficult to perform during general anesthesia. The peripheral perfusion index (PI) is another noninvasive method for evaluating peripheral perfusion. The PI can easily and continuously evaluate peripheral perfusion and could be an alternative to CRT for use during general anesthesia. This study aimed to determine the cutoff PI value for low peripheral perfusion status (prolonged CRT) by exploring the relationship between CRT and the PI during general anesthesia.

Methods:
We enrolled 127 surgical patients. CRT and the PI were measured in a hemodynamically stable state during general anesthesia. A CRT >3 s indicated a low perfusion status.

Results:
Prolonged CRT was observed in 27 patients. The median PI values in the non-prolonged and prolonged CRT groups were 5.0 (3.3–7.9) and 1.5 (1.2–1.9), respectively. There was a strong negative correlation between the PI and CRT (r = −0.706). The area under the receiver operating characteristic curve generated for the PI was 0.989 (95% confidence interval, 0.976–1.0). The cutoff PI value for detecting a prolonged CRT was 1.8.

Conclusion:
A PI <1.8 could accurately predict a low perfusion status during general anesthesia in the operating room. A PI <1.8 could be used to alert the possibility of a low perfusion status in the operating room.

Trial Registration:
University Hospital Medical Information Network (UMIN000043707; retrospectively registered on March 22, 2021, https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049905).
Awareness, preconception, and fear of epidural analgesia among childbearing women in Saudi Arabia
Authors: Aldammas Fatma , Alshihri Abdulrhman A. , Alhowaish Rayan K. , Alotaibi Basheer M. , Alhamdi Abdullah F. , Algharbi Faisal F. , Alhassoun Hamad Y. , Alhamad Mohammed H. , Alhaddab Abdullah A. 
Published: December 2022

Background:
Labor pain is one of the most excruciatingly painful sensations a woman can have. A woman's attitude toward childbirth might be influenced by her lack of understanding of the birth process and the pain she experiences throughout labor and delivery. The control of pain is an important aspect of appropriate obstetrical care. Our study aims to measure the level of awareness, preconception, and fear of epidural analgesia (EDA) among childbearing women.

Methods:
An observational cross-sectional, hospital-based study was conducted using a self-administered questionnaire. The study included all pregnant women who were attending an obstetrical clinic for routine antenatal follow-up at King Khalid university hospital in Riyadh, Saudi Arabia, during the month of August 2022. They were asked about five main parts that tapped their awareness, preconception, and fear of EDA. Data were analyzed by SPSS version 26 using descriptive methods, including mean, frequency, and percentage, and also Pearson's correlation coefficient for regression analysis to find the correlation between socio-demographics and awareness and between awareness and fear.

Results:
Participants in our study included 202 childbearing women. Most women, about 113 (55.9%), participating in the study were aged between 25 and 34 years old. The majority of the participants of this study were Saudi, about 196 (97.0%). In terms of education, 120 (59.4%) of the participants graduated from university. One hundred and forty two (70.3%) of the participants had a monthly income of less than 10000. When it comes to parity, the majority of participants, about 102 (50.5%), have had more than two pregnancies. The average percentage of awareness among the participants showed 45.9%, with an insignificant very moderate correlation between parity and awareness (r = -0.088, P = 0.107); women's knowledge, income, and age were also insignificantly related to awareness. Also, the result showed a moderate level of fear with an average percentage of 44.6% among the participants, with a moderate correlation between awareness and fear with a value of (r = 0.184, P = 0.004).

Conclusion:
This study results demonstrate a good level of desirability toward using EDA for labor pain, yet there is a limited level of preconceptions and a low level of awareness and knowledge about EDA. In addition, the results showed that the average percentage of fear is 44.6%. Therefore, we suggest that more awareness, knowledge, and guidance about EDA should be provided to pregnant women through antenatal clinics. Furthermore, educational campaigns should be made to dispel misconceptions and fears about EDA.
Bases for upper cluster algebras and tropical points
Authors: Qin Fan 
Published: December 2022

It is known that many (upper) cluster algebras possess different kinds of good bases which contain the cluster monomials and are parametrized by the tropical points of cluster Poisson varieties. For a large class of upper cluster algebras (injective-reachable ones with full rank coefficients), we describe all of their bases with these properties. Moreover, we show the existence of the generic basis for them. In addition, we prove that Bridgeland’s representation-theoretic formula is effective for their theta functions (weak genteelness).
Our results apply to (almost) all known cluster algebras arising from representation theory or higher Teichmüller theory, including quantum affine algebras, unipotent cells, double Bruhat cells, skein algebras over surfaces, where we change the coefficients if necessary so that the full rank assumption holds.
Optimalisasi Kinerja Perum Bulog dalam Menyerap Hasil Panen Petani di Distrik Kurik
Authors: Hubertus  , Teturan Yohanes E , Adnan Rasdi 
Published: December 2022

The issue of rice procurement is still in the spotlight and focus for every organization to survive in the current era of globalization. This research purpose of this study is to analyze the performance of Perum Bulog in handling farmers' harvests in Kurik District. The research method uses a qualitative descriptive approach. The research results on Bulog handling farmers' rice in Kurik District, Merauke Regency, have yet to run optimally in the absorption of farmers' rice products. This happens because the rice skins produced by farmers do not follow the rice quality standards determined by Bulog. As a recommendation, research needs to bridge the demands and needs of farmers so that the harvest can be maximized and optimize local governments' role in training farmers. Thus, farmers will have the necessary means to optimize their crops in quality and quantity.
Abstrak
Permasalahan pengadaan beras masih menjadi sorotan dan tumpuan bagi setiap organisasi agar dapat bertahan di era globalisasi pada saat ini. Tujuan dari penelitian ini adalah untuk menganalisis kinerja Perum Bulog dalam menangani hasil panen petani di Distrik Kurik. Metode penelitian menggunakan pendekatan kualitatif. Data penelitian dikumpulkan melalaui wawancara, sedengkan untuk analisis data berupa: reduksi data; penyajian data, serta penarikan kesimpulan. Hasil penelitian kinerja perum bulog dalam menyerap beras petani di Distrik Kurik Kabupaten Merauke belum berjalan secara maksimal dalam penyerapan hasil beras petani. Hal ini terjadi karena kualitas beras petani yang dihasilkan belum semua sesuai dengan standar kualiats beras yang sudah ditentukan oleh bulog. Efektivitas kinerja Perum Bulog belum efektif karena di lapangan masih banyak beras yang belum terserap secara keseluruhan. Produktifitas Perum Bulog belum maksimal dalam menyerap beras yang dihasilkan petani, penyerapan beras hanya yang memenuhi standar dan beras yang tidak memenuhi standar dikembalikan. Perum Bulog seharusnya memiliki alternatif lain dalam menampung beras yang belum memenuhi standar dengan sistem perawatan. Rekomendasi penelitian optimalisasi peran pemerintah daerah sangat diperlukan dalam bentuk pelatihan sistem pengelolaan sawah yang terpadu agar petani dapat memiliki pengetahuan dalam penanaman, pra panen, dan pasca panen agar hasil panen dapat dimaksimalkan baik secara kualitas maupun kuantitasnya.
THE CHARACTERISTICS LEVEL OF MATERNAL SATISFACTION IN RECEIVING ANTENATAL CARE (ANC)
Authors: Mutianingsih Rosa , Mardiningsih Siti 
Published: December 2022

The low working capacity of puskesmas midwives in health care facilities is one indicator of low work effectiveness, as well as service satisfaction for pregnant women . The purpose of this study was to identify the level of maternal satisfaction about obstetric examination services antenatal care (ANC) by health workers at Karang Pule Health Center. Research design using descriptive survey research methods . the population, namely all pregnant women who did ANC at the Karang Pule Health Center in January to June 2020, was 96 people. Sampling technique Accidental sampling. Number of samples as many as 30 respondents, how to process data using Likert scale. From the results showed that the level of maternal satisfaction in the acceptance of ANC examination services in general from the aspect of Tangibles, expressed satisfaction as many as 23 respondents (76.67%), Reliability expressed satisfaction as many as 23 respondents (76.67%), Responsivenes expressed satisfaction as many as 24 respondents (80%), assurance expressed satisfaction as many as 22 respondents (73.33%),Emphaty expressed satisfaction as many as 24 respondents (80%), the results of this study concluded 78, 38% expressed satisfaction. It is expected from the results of this study to be one of the inputs on the need to improve the attention and standards of ANC services in health centers