bluuebunny/crossref_metadata_2025_split huggingface dataset:
Situations of work-related diseases and injuries among agriculturists in the upper northeast regions of Thailand
Authors: Chaiklieng Sunisa , Chagkornburee Chuthamas , Suggaravetsiri Pornnapa 
Published: May 2023

Background: Agriculturists exposed to health hazards are affected by increased occupational disease. This retrospective study aimed to investigate situations of work-related diseases and injuries among agriculturists in upper northeast Thailand. Methods: The secondary data of international classification of diseases 10 th revision (ICD-10) case reports of occupational disease among farmers, from the database of the Health Data Center (HDC), were used. The registered farmers’ data was collected as a dataset from the provincial agricultural office and the data of the ICD-10 code, which was utilized from the hospital information system (HIS) of healthcare services in Udon Thani and Roi-Et provinces, was extracted for cases of work-related diseases and injuries of registered agriculturists. The annual morbidity rate of occupational diseases was analyzed and presented as a rate per 100,000 farmers. Results: Among diseases of farmers in the HDC database, lung disease, which was not reported as an occupational disease of the HDC database, was the highest ranking of all diseases, followed by work-related musculoskeletal disorders (WMSDs), noise- and heat-related diseases, and pesticide toxicity, respectively, while the injury rate was as high as that of WMSDs. Those morbidity rates of Roi-Et and Udon Thani provinces were representative of the morbidity ranking of diseases of the nation and had increasing trends from 2014 to 2016. The number of farmers in the HDC database did not consistently reflect the number of registered farmers in the agricultural database. Conclusions: Situations of work-related diseases and injuries discovered among registered farmers reflect the health problems of Thai agriculturists, and the underestimation in the reported disease rate in the health database is explained by big data analysis, which showed that work-related cases with an identifying code of Y96 had rarely been reported among agriculturists. Therefore, the agriculturists should be supported in registration for occupational diseases and injuries surveillance.
Do the benefits outweigh the risks? Potential dangers associated with long-term therapy of proton pump inhibitors
Authors: Wolanin Izabela , Zielonka Bartłomiej , Dengler Barbara , Madej Karolina , Wolanin Marta , Stachyra Bartłomiej , Stawikowski Cezary , Osińska Aleksandra , Kowalczyk Ilona , Krasa Aleksandra 
Published: May 2023

Introduction:Proton pump inhibitors (PPIs) are one of the most popular and also one of the most commonly prescribed medications worldwide. In many conditions associated with excessive secretion of hydrochloric acid in the stomach, they are the first-line treatment. When they are used in a balanced manner in strict indications, they have a high level of efficacy and a favorable safety profile. The low rate of side effects refers mainly to their short-term use. With the over-the-counter availability of PPIs, increasing dangerous trend of their abuse has provided new evidence suggesting the presence of numerous, more serious side effects of long-term PPI therapy.
Purpose:The purpose of this review is to summarize current reports regarding the potential risks and causal relationship of adverse effects occurring as a consequence of long-term use of proton pump inhibitors.
Material and methods:This literature review based on the available scientific literature, published between 2015 and 2023 in the Pubmed database, searched using the terms, listed under "keywords”.
Conclusion:PPIs are relatively safe drugs. However, they are not completely free of side effects. There are a lot of reports suggesting a potential connection between their long-term use and the development of complications, such as: various infections, decreased absorption of nutrients, kidney disease, liver disease, pancreatic disease, musculoskeletal disease, nervous system disease, cardiovascular disease, dementia, hypergastrinemia and even cancer. However, some of them are fraught with errors, and another often provide contradictory results. More precisely designed studies are needed to draw clear conclusions, especially in view of the ever-increasing abuse of PPIs worldwide. It is worth noting that patients with strictly defined indications for long-term PPI therapy, may benefit significantly outweighing the potential dangers.
Move Fast and Break Things? The Contingent Nature of Product Acceleration in Nascent Markets
Authors: Lu Xuege (Cathy) , Lee Hyeonsuh , Coles Ryan 
Published: May 2023

Acceleration allows firms to lock in early success upon entering a nascent market, but whether it enables firms to sustain competitive advantage after the entry is unclear. Using a granular data set on the U.S. LED lightbulb market 2010–2017, we apply an abductive approach to examine the relationship between postentry product acceleration and market acceptance. We find that, although acceleration is slightly more beneficial for firms that have accumulated greater pioneering experience, incumbents with more recognizable brands are able to achieve even greater market acceptance by slowing down their product iterations. Meanwhile, deceleration seems to be a better strategy among firms striving to build legitimacy via regulatory engagement, whereas acceleration could be more beneficial for firms competing in subproduct markets with greater technological uncertainties. We contribute to the nascent market literature by showing that the extent to which firms gain market acceptance through postentry product acceleration hinges on their abilities to assess, learn from, and shape both market and nonmarket stakeholders. Funding: This research is supported by grants from the Innovation, Entrepreneurship, and Technology Research Grant provided by Cornell University’s Johnson College of Business and Daigle Labs at the University of Connecticut, School of Business. Supplemental Material: The online appendices are available at https://doi.org/10.1287/stsc.2023.0192 .
Exploring midwives' emotional wellbeing: evaluation of a survey using cognitive interviews
Authors: Dent Jackie , Smeeton Nigel , Whiting Lisa , Watson Tim 
Published: May 2023

Background/Aims Surveys are a popular method of collecting data to explore factors associated with midwives' emotional wellbeing. However, existing survey instruments lack consideration of how working practices may influence outcomes. This study aimed to test the face and content validity of a new instrument by assessing midwives' comprehension of bespoke survey items. Methods A total of 24 cognitive interviews were conducted with midwives working across the UK. A framework matrix method facilitated descriptive and explanatory analysis of the interpretation of survey items. Interviews were followed by a discussion group with midwifery academics to help identify optimal wording of one problematic survey question. Results A range of potential comprehension and response problems were identified, resulting in modifications and the addition of new survey items. Conclusions Cognitive interviews can be an effective method to confirm the relevance and usability of bespoke survey items and offer opportunities to improve wording to reduce potential sources of error, thus enhancing the face and content validity of surveys.
What is the ‘voltage drop’ when an effective health promoting intervention for older adults—Choose to Move (Phase 3)—Is implemented at broad scale?
Authors: McKay Heather A. , Macdonald Heather M. , Nettlefold Lindsay , Weatherson Katie , Gray Samantha M. , Bauman Adrian , Khan Karim M. , Sims Gould Joanie 
Published: May 2023

BackgroundChoose to Move (CTM), an effective health-promoting intervention for older adults, was scaled-up across British Columbia, Canada. Adaptations that enable implementation at scale may lead to ‘voltage drop’—diminished positive effects of the intervention. For CTM Phase 3 we assessed: i. implementation; ii. impact on physical activity, mobility, social isolation, loneliness and health-related quality of life (impact outcomes); iii. whether intervention effects were maintained; iv) voltage drop, compared with previous CTM phases.MethodsWe conducted a type 2 hybrid effectiveness-implementation pre-post study of CTM; older adult participants (n = 1012; mean age 72.9, SD = 6.3 years; 80.6% female) were recruited by community delivery partners. We assessed CTM implementation indicators and impact outcomes via survey at 0 (baseline), 3 (mid-intervention), 6 (end-intervention) and 18 (12-month follow-up) months. We fitted mixed-effects models to describe change in impact outcomes in younger (60–74 years) and older (≥ 75 years) participants. We quantified voltage drop as percent of effect size (change from baseline to 3- and 6-months) retained in Phase 3 compared with Phases 1–2.ResultsAdaptation did not compromise fidelity of CTM Phase 3 as program components were delivered as intended. PA increased during the first 3 months in younger (+1 days/week) and older (+0.9 days/week) participants (p<0.001), and was maintained at 6- and 18-months. In all participants, social isolation and loneliness decreased during the intervention, but increased during follow-up. Mobility improved during the intervention in younger participants only. Health-related quality of life according to EQ-5D-5L score did not change significantly in younger or older participants. However, EQ-5D-5L visual analog scale score increased during the intervention in younger participants (p<0.001), and this increase was maintained during follow-up. Across all outcomes, the median difference in effect size, or voltage drop, between Phase 3 and Phases 1–2 was 52.6%. However, declines in social isolation were almost two times greater in Phase 3, compared with Phases 1–2.ConclusionBenefits of health-promoting interventions—like CTM—can be retained when implemented at broad scale. Diminished social isolation in Phase 3 reflects how CTM was adapted to enhance opportunities for older adults to socially connect. Thus, although intervention effects may be reduced at scale-up, voltage drop is not inevitable.
Association between occupational exposures and chronic low back pain: Protocol for a systematic review and meta-analysis
Authors: Jahn Alexander , Andersen Johan Hviid , Christiansen David Høyrup , Seidler Andreas , Dalbøge Annett 
Published: May 2023

Introduction
The association between occupational mechanical exposures and chronic low back pain (LBP) has been widely studied, however, few systematic reviews have evaluated the evidence of an association. Furthermore, little is known of the impact of occupational psychosocial exposures on chronic LBP. The aim of this systematic review and meta-analysis is to study the association between occupational mechanical and psychosocial exposures and chronic LBP.

Methods
The study will be conducted as a systematic review using another systematic review published in 2014 as basis and has been registered in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number CRD42021281996. A systematic literature search will be performed in 6 scientific databases to identified potential relevant studies published after 2014. Studies will systematically be excluded through a screening process performed independently by 2 reviewers. Exposures will include occupational mechanical and psychosocial exposures, and outcome will include chronic LBP (LBP ≥3 months, “degenerative” diseases, and lumbosacral radiculopathy). Study population will include persons in or above working age, and study designs will comprise cohort and case-control studies. The quality of each included study will be methodologically assessed by 2 independent reviewers and level of evidence of an association will be graded using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) system. In meta-analyses, effect sizes will be addressed using random-effect models, sensitivity analyses will explore the robustness of the meta-analysis, and heterogeneity assessed.

Discussion
This systematic review and meta-analysis will assess the evidence available of the association between occupational mechanical and psychosocial exposures and chronic LBP. The review can provide essential knowledge on the association, exposure-response relationships, thresholds, which may pave the way for political decisions on the occupational environment and the labour market insurance policy.
Content validity of the Scoliosis Research Society questionnaire (SRS-22r): A qualitative concept elicitation study
Authors: Alamrani Samia , Gardner Adrian , Falla Deborah , Russell Emily , Rushton Alison B. , Heneghan Nicola R. 
Published: May 2023

IntroductionScoliosis Research Society-22 revised (SRS-22r) is the common questionnaire used to evaluate health related quality of life (HRQOL) for young people with adolescent idiopathic scoliosis (AIS). The aim of this study is to evaluate its content validity for this population.MethodsIn-depth semi-structured interviews were conducted with a purposive sample of young people with AIS (Cobb angle ≥25˚, aged 10–18 years). Concept elicitation was used to evaluate the influence of AIS on participants’ HRQOL. Participant information sheets and consent/assent forms were age relevant. Topic guide was informed by the SRS-22r and existing evidence. Interviews were audio and video recorded, transcribed verbatim, coded, and analysed using thematic analysis. Derived themes/codes were compared with SRS-22r contents (domains/items).ResultsEleven participants (mean age 14.9 years [SD = 1.8]; 8 female) were recruited. The mean curve size was 47.5° [SD = 18°] and participants had been managed via different approaches. Four main themes emerged with associated subthemes: 1) Physical effects related to physical symptoms (back hurt, stiffness) and body asymmetry (uneven shoulders), 2) Activity-related effects showed impact on mobility (sitting for long periods), self-care (dressing), and school activities (focus during lessons), 3) Psychological effects revealed emotional (feel worried), mental (sleep quality), and body image effects (hide back from others), 4) Social effects (participation in school and leisure activities), and school, friends and mental health support. A weak association was found between items of the SRS-22r and the identified codes.ConclusionThe SRS-22r does not adequately capture important concepts that relate to HRQOL of adolescents with AIS. These findings support revision of the SRS-22r, or the development of a new patient reported outcome measure to evaluate HRQOL of adolescents with AIS.
VALIDITAS ISI SKALA INTEGRITAS AKADEMIK DOSEN
Authors: Widodo Prasetya Budi , Rusmawati Diana , Mujiasih Endah , Dinardinata Adi 
Published: May 2023

Integritas akademik adalah kualitas individu-individu dalam lembaga pendidikan yang selalu diupayakan untuk menjadi semakin baik dari waktu ke waktu. Penelitian ini bertujuan untuk menguji validitas isi skala integritas akademik dosen. Item yang dikembangkan dalam penelitian ini menggunakan desain situational judgement test (SJT) yang terdiri dari sebuah skenario dan 4 opsi respon. Validasi isi dilakukan kepada indikator keperilakuan dan item yang disusun peneliti dengan batas nilai Aiken sebesar 0,8. Ahli yang dilibatkan dalam penelitian ini sejumlah 21 orang. Hasil analisis dengan Aiken’s V menunjukkan skala integritas akademik dosen yang dikembangkan dalam penelitian ini mempunyai validitas isi yang baik, dengan nilai V lebih dari 0,8 pada pengujian validitas isi indikator perilaku aspek integritas akademik maupun pengujian validitas isi pada 96 item skala integritas akademik.
PENGARUH SUHU EKSTRAKSI PADA METODE DRY RENDERING TERHADAP KUALITAS MINYAK KASAR HATI IKAN MANYUNG (Arius thalassinus)
Authors: Efendi Sindi Clarista , Anggo Apri Dwi , Wijayanti Ima 
Published: May 2023

Suhu ekstraksi pada pengolahan minyak hati ikan manyung akan mempengaruhi kualitas minyak yang dihasilkan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perbedaan suhu ekstraksi terhadap kualitas minyak hati ikan manyung yang dihasilkan. Penelitian bersifat experimental laboratories dengan model rancangan acak lengkap (RAL). Faktor perlakuan yaitu perbedaan suhu ekstraksi (60˚C, 70˚C dan 80˚C) dengan lama pemanasan 20 menit dan ulangan sebanyak tiga kali. Metode ekstraksi minyak menggunakan metode dry rendering dengan parameter yang diamati berupa rendemen, angka iod, bilangan penyabunan, kadar lemak dan sensori. Data dianalisis menggunakan uji ANOVA dan dilanjutkan dengan uji. Hasil penelitian menunjukkan perlakuan perbedaan suhu ektraksi telah memberikan pengaruh nyata terhadap parameter rendemen minyak yang dihasilkan, angka iod, bilangan penyabunan, kadar lemak dan nilai sensorinya. Suhu ekstraksi terbaik bagi minyak hati ikan manyung adalah 70oC selama 20 menit dengan kriteria rendemen sebanyak 3,27±0,57%, angka iodine sebesar 113,13±0,59 mg/g, bilangan penyabunan sebesar 135,21±0,61 mg.KOH/g, kadar lemak 93,03±0,74% dan rata-rata nilai sensori sebesar 56±0,3. Semakin naik suhu ekstraksi maka parameter angka iod, bilangan penyabunan dan sensori semakin menurun, sedangkan kadar lemak dan rendemennya meningkat.
APLIKASI TEKNOLOGI IONISASI TEGANGAN TINGGI UNTUK PENGAWET IKAN TONGKOL (Euthynnus affinis)
Authors: Melantina Diana , Swastawati Fronthea , Syakur Abdul 
Published: May 2023

Ikan tongkol merupakan salah satu produk perairan yang rentan terhadap kemunduran mutu dan umur simpan yang singkat. Salah satu cara untuk memperlambat penurunan mutu ikan segar adalah dengan menambahkan ozon selama penyimpanan. Ozon dipilih sebagai pengawet ikan karena ozon merupakan senyawa yang dapat membunuh bakteri dan memiliki kemampuan oksidasi yang kuat. Ikan segar membutuhkan proses pengawetan yang baik untuk memperlambat penurunan mutu dan memperpanjang umur simpan. Proses pengawetan ikan dilakukan dengan cara ikan dicuci dengan air bersih, ikan ditimbang, ikan diletakkan pada chamber, selanjutnya ikan diawetkan menggunakan ozon. Analisa terdiri dari organoleptik, kadar air, kadar lemak, kadar protein, dan TPC. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pengawetan dengan ozon terhadap karakteristik ikan tongkol dengan lama pengawetan terbaik. Metode penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan perlakuan lama waktu pengawetan (0 menit, 30 menit dan 60 menit) sebanyak 3 kali ulangan. Data yang diperoleh diuji dengan uji normalitas, uji homogenitas, analisis sidik ragam (ANOVA), dan beda nyata jujur (BNJ) untuk mengetahui perbedaan nyata pada perlakuan. Hasil analisa data menunjukkan bahwa ozon dengan lama waktu pengawetan yang berbeda mempunyai pengaruh yang berbeda nyata (P<5%) terhadap semua parameter uji yaitu organoleptik, kadar air, kadar lemak, kadar protein dan TPC. Berdasarkan hasil penelitian, ikan tongkol terbaik yaitu lama pengawetan menggunakan ozon selama 30 menit dengan nilai organoleptik 7,93 ≤ µ ≤ 7,99, kadar air 72,09 0,20 (%), kadar lemak 1,44 0,03 (%), kadar protein 26,20 0,15 (%), dan TPC 1,3 x 103(CFU/ml).
PENGARUH KOMBINASI LEACHING DAN EGG WHITE POWDER (EWP) TERHADAP KUALITAS GEL KAMABOKO IKAN COBIA (Rachycentron Canadum)
Authors: Firmansyah Ardya Risma , Anggo Apri Dwi , Purnamayati Lukita 
Published: May 2023

Kamaboko merupakan salah satu produk berbasis lumatan daging ikan yang ditambahkan tepung, gula dan garam. Ikan sebagai bahan baku utama kamaboko memiliki kelemahan yaitu mudah mengalami kerusakan tekstur saat pengolahan akibat menurunnya kekuatan gel pada daging sehingga diperlukan perlakuan untuk meningkatkan kekuatan gel kamaboko. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi leaching dan EWP 3% terhadap kualitas kamaboko ikan cobia dan menentukan pengaruh perlakuan terbaik terhadap kekuatan gel kamaboko ikan cobia. Metode penelitian yang digunakan adalah experimental laboratories menggunakan model RAL (Rancangan Acak Lengkap) dengan perlakuan leaching 1 kali (K), leaching 3 kali (A), leaching 1 kali dan penambahan EWP 3% (B), leaching 3 kali dan penambahan EWP 3% (C) dengan 3 kali ulangan. Data kekuatan gel, daya ikat air, derajat putih, kadar air, kadar protein dianalisis menggunakan ANOVA dan BNJ. Data uji lipat dan uji gigit dianalisis menggunakan Kruskall-Wallis dan uji lanjut Mann-Whitney. Hasil penelitian menunjukkan bahwa kombinasi leaching dan EWP 3% memberikan pengaruh nyata (p<0,05) terhadap nilai kekuatan gel, daya ikat air, derajat putih, kadar air, kadar protein, uji lipat dan uji gigit. Kamaboko ikan cobia dengan perlakuan leaching 3 kali dan penambahan EWP 3% merupakan produk dengan hasil terbaik dengan karakteristik: kekuatan gel 1453,48 g.cm, daya ikat air 20,9%, derajat putih 72,62%, kadar air 69,24%, kadar protein 20,87%.
Sifat Organoleptik Sambal Pecel UKM Hj Sartinah Semarang Selama Masa Penyimpanan Suhu Ruang
Authors: Azizah Amalina Nur , Setiani Bhakti Etza , Pramono Yoyok Budi 
Published: May 2023

Penelitian ini bertujuan untuk mengetahui kualitas sambal pecel dari segi sifat organoleptik pada kemasan yang berbeda serta mengetahui kemasan yang lebih baik untuk sambal pecel selama masa penyimpanan 8 minggu. Perlakuan kemasan plastik vakum dan kemasan aluminium foil masing – masing terdiri dari 3 kali ulangan dan disimpan pada suhu ruangan selama 8 minggu. Aspek organoleptik yang dinilai meliputi aroma, warna, tektur, kesukaan rasa, dan kesukaan overall dianalisis menggunakan Kruskal Wallis program SPSS 21.0. Hasil penelitian dilihat dari aspek sifat organoleptik menunjukkan bahwa selama penyimpanan 8 minggu kualitas sambal pecel kemasan aluminium foil lebih baik dibandingkan dengan kemasan plastik vakum. Panelis lebih menerima sambal pecel dengan kemasan aluminium foil.
Studi Apoptosis Pada Daging Itik dan Ayam melalui Perubahan pH
Authors: Lumbantoruan Julia Ester , Setiani Bhakti Etza , Al-Baarri Ahmad Ni'matullah , Sutopo Sutopo , Kurnianto Edy 
Published: May 2023

Apoptosis merupakan kematian sel yang terjadi saat pengkonversian daging yang berkaitan erat dengan kualitas daging. Salah satu parameter studi apoptosis adalah perubahan pH. Analisis pH dilakukan dengan menggunakan pH meter. Penelitian ini bertujuan untuk menganalisis nilai pH pada daging itik dan ayam yang disimpan selama 8 jam pada suhu ruang. Berdasarkan penelitian ini dapat diketahui bahwa nilai pH pada daging itik secara berturut-turut sebesar 6,70±0,21; 6,66±0,13; 6,64±0,31; 6,51±0,25 dan 6,50±0,19 sedangkan pada daging ayam sebesar 5,66±0,16; 5,59±0,11; 5,56±0,25; 5,52±0,16 dan 5,45±0,16. Penyimpanan daging pada suhu ruang menyebabkan penurunan nilai pH daging itik sebesar 0,20% dan daging ayam sebesar 0,21%. Apoptosis is a death cell that occurs when meat conversion is closely related to meat quality. One of the parameters of study apoptosis is pH change. pH analysis was performed using pH meter. This study aims to analyze the pH value of duck and chicken meat stored for 8 hours at room temperature. Based on this research it can be seen that the pH value in duck meat in a row is 6.70 ± 0.21; 6.66 ± 0.13; 6.64 ± 0.31; 6.51 ± 0.25 and 6.50 ± 0.19 whereas chicken meat was 5.66 ± 0.16; 5.59 ± 0.11; 5.56 ± 0.25; 5.52 ± 0.16 and 5.45 ± 0.16. Storage of meat at room temperature caused a decrease in the value of pH of duck meat by 0.20% and chicken meat by 0.21%.