bluuebunny/crossref_metadata_2025_split huggingface dataset:
Imaging Recommendations for Diagnosis, Staging, and Management of Pancreatic Cancer
Authors: Shetty Nitin Sudhakar , Agarwal Ujjwal , Choudhari Amit , Gupta Anurag , PG Nandakumar , Bhandare Manish , Gala Kunal , Chandra Daksh , Ramaswamy Anant , Ostwal Vikas , Shrikhande Shailesh V. , Kulkarni Suyash S. 
Published: March 2023

AbstractPancreatic cancer is the fourth most prevalent cause of cancer-related death worldwide, with a fatality rate equal to its incidence rate. Pancreatic cancer is a rare malignancy with a global incidence and death ranking of 14th and 7th, respectively. Pancreatic cancer cases are divided into three categories without metastatic disease: resectable, borderline resectable, or locally advanced disease. The category is determined by the tumor's location in the pancreas and whether it is abutting or encasing the adjacent arteries and/or vein/s.The stage of disease and the location of the primary tumor determine the clinical presentation: the pancreatic head, neck, or uncinate process, the body or tail, or multifocal disease. Imaging plays a crucial role in the diagnosis and follow-up of pancreatic cancers. Various imaging modalities available for pancreatic imaging are ultrasonography (USG), contrast-enhanced computed tomography (CECT), magnetic resonance imaging (MRI), and 18-fluoro-deoxy glucose positron emission tomography (FDG PET).Even though surgical resection is possible in both resectable and borderline resectable non-metastatic cases, neoadjuvant chemotherapy with or without radiotherapy has become the standard practice for borderline resectable cases as it gives a high yield of R0 resection.
Corifollitropin Alfa for Controlled Ovarian Stimulation in Assisted Reproductive Technologies: State of the Art
Authors: Carvalho Bruno Ramalho de 
Published: March 2023

AbstractPhysical and emotional burdens during the journey of infertile people through assisted reproductive technologies are sufficient to justify the efforts in developing patient-friendly treatment strategies. Thus, shorter duration of ovarian stimulation protocols and the need for less injections may improve adherence, prevent mistakes, and reduce financial costs. Therefore, the sustained follicle-stimulating action of corifollitropin alfa may be the most differentiating pharmacokinetic characteristic among available gonadotropins. In this paper, we gather the evidence on its use, aiming to provide the information needed for considering it as a first choice when a patient-friendly strategy is desired.
Imaging Recommendations for Diagnosis, Staging, and Management of Gastric Cancer
Authors: Chatterjee Argha , Shah Diva , Roy Bipradas , Ghosh Joydeep , Ray Soumendranath , Patra Anurima , Gehani Anisha , Gupta Bharat , Ghosh Priya , Mukhopadhyay Sumit , Chandra Aditi , Lingegowda Dayananda , Sen Saugata 
Published: March 2023

AbstractGastric cancer is the second most common cause of cancer-related death in Indian men and women aged between 15 and 44 years. Most patients present at an advanced stage of disease. Surgically resectable disease usually requires a standard gastric resection and D2 lymphadenectomy. Imaging, especially with computed tomography scan of abdomen as well as thorax, is necessary for localization, nodal mapping, and metastatic workup of gastric cancer. In this review, we discuss current imaging recommendations for gastric carcinoma.
Multisystem Imaging Recommendations/Guidelines: In the Pursuit of Precision Oncology
Authors: Mahajan Abhishek , Chakrabarty Nivedita , Majithia Jinita , Ahuja Ankita , Agarwal Ujjwal , Suryavanshi Shubham , Biradar Mahesh , Sharma Prerit , Raghavan Bagyam , Arafath Rasheed , Shukla Shreya 
Published: March 2023

AbstractWith an increasing rate of cancers in almost all age groups and advanced screening techniques leading to an early diagnosis and longer longevity of patients with cancers, it is of utmost importance that radiologists assigned with cancer imaging should be prepared to deal with specific expected and unexpected circumstances that may arise during the lifetime of these patients. Tailored integration of preventive and curative interventions with current health plans and global escalation of efforts for timely diagnosis of cancers will pave the path for a cancer-free world. The commonly encountered circumstances in the current era, complicating cancer imaging, include coronavirus disease 2019 infection, pregnancy and lactation, immunocompromised states, bone marrow transplant, and screening of cancers in the relevant population. In this article, we discuss the imaging recommendations pertaining to cancer screening and diagnosis in the aforementioned clinical circumstances.
Meta-analysis and Construction of Core Indicator Field of Pediatric Bronchitis Treated by Chinese Herbs Acupoint Application Therapy
Authors: Qian Zhenzhen , Li Rui , Duan Juan , Jing Zhiwei , Gao Rui 
Published: March 2023

Abstract
Objective Our objective was to explore the commonly used herbs, acupoints, and efficacy evaluation indicators of Chinese herbs acupoint application therapy in the treatment of pediatric bronchitis, screen and construct the core index field, and systematically evaluate the efficacy and safety of Chinese herbs acupoint application therapy in the treatment of this disease.
Methods Chinese periodical databases such as China National Knowledge Infrastructure, Wanfang database, VIP Information, and Chinese Biomedical Literature database were searched, and the literature information was extracted manually to establish data tables for data analysis and the key efficacy evaluation index field. The quality of the included studies was assessed using the Cochrane Systematic Bias Risk Assessment Tool and the relevant efficacy indicators were meta-analyzed using RevMan 5.3 software.
Results The most commonly used herbs in acupoint application therapy were wind-cold dispersing herbs and cough-asthma relieving herbs. Feishu (BL 13), Danzhong (RN 17), and Tiantu (RN 22) were the main acupoints. The core indicators were effective rate, improvement of main symptoms/signs, onset time, disappearance time, traditional Chinese medicine (TCM) syndrome score, and symptom score. Meta-analysis results showed that the total effective rate was 0.11 (0.08, 0.33) (Z = 8.64, p < 0.00001), I
2 = 39%; due to the heterogeneity of cough, expectoration, asthma, and other indicators, the meta-analysis was abandoned.
Conclusion In terms of total efficiency, Chinese medicine acupoint application therapy is superior to conventional Western medicine in efficacy and shortening the time of symptoms of pediatric asthmatic bronchitis. However, as the quality of the evidence included in the study is medium and low, and in the selection of indicators, there are more composite and relatively subjective indicators such as total effective rate, TCM syndrome score, and symptom score. Therefore, it is necessary to further standardize the efficacy indicators in this field and carry out high-quality and detailed Chinese medicine clinical randomized controlled trials.
Cervical Cancer Screening with DNA-HPV Testing and Precancerous Lesions Detection: A Brazilian Population-based Demonstration Study
Authors: Teixeira Julio Cesar , Vale Diama Bhadra , Discacciati Michelle Garcia , Campos Cirbia Silva , Bragança Joana Froes , Zeferino Luiz Carlos 
Published: March 2023

Abstract
Objective To evaluate the rates of precancerous lesions, colposcopy referral, and positive predictive value (PPV) by age groups of a population-based screening with DNA-HPV testing.
Methods The present demonstration study compared 16,384 HPV tests performed in the first 30 months of the program with 19,992 women tested in the cytology screening. The colposcopy referral rate and PPV for CIN2+ and CIN3+ by age group and screening program were compared. The statistical analysis used the chi-squared test and odds ratio (OR) with 95% confidence interval (95%CI).
Results The HPV tests were 3.26% positive for HPV16-HPV18 and 9.92% positive for 12 other HPVs with a 3.7 times higher colposcopy referral rate than the cytology program, which had 1.68% abnormalities. Human Papillomavirus testing detected 103 CIN2, 89 CIN3, and one AIS, compared with 24 CIN2 and 54 CIN3 detected by cytology (p < 0.0001). The age group between 25 and 29 years old screened by HPV testing had 2.4 to 3.0 times more positivity, 13.0% colposcopy referral, twice more than women aged 30 to 39 years old (7.7%; p < 0.0001), and detected 20 CIN3 and 3 early-stage cancer versus 9 CIN3 and no cancer by cytology screening (CIN3 OR= 2.10; 95%CI: 0.91–5.25; p = 0.043). The PPV of colposcopy for CIN2+ ranged from 29.5 to 41.0% in the HPV testing program.
Conclusion There was a significant increase in detections of cervix precancerous lesions in a short period of screening with HPV testing. In women < 30 years old, the HPV testing exhibited more positivity, high colposcopy referral rate, similar colposcopy PPV to older women, and more detection of HSIL and early-stage cervical cancer.
Predictive Factors of Tolerance in Office Hysteroscopy – a 3-Year Analysis from a Tertiary Center
Authors: Coimbra Ana Carolina , Falcão Vera , Pinto Pedro , Cavaco-Gomes João , Fernandes Ana Sofia , Martinho Margarida 
Published: March 2023

Abstract
Objective Pain is the primary limitation to performing hysteroscopy. We aimed to evaluate the predictive factors of low tolerance to office hysteroscopic procedures.
Methods Retrospective cohort study of the patients who underwent office hysteroscopy from January 2018 to December 2020 at a tertiary care center. Pain tolerance to office-based hysteroscopy was subjectively assessed by the operator as terrible, poor, moderate, good, or excellent. Categorical variables were compared with the use of the Chi-squared test; an independent-samples t-test was conducted to compare continuous variables. Logistic regression was performed to determine the main factors associated with low procedure tolerance.
Results A total of 1,418 office hysteroscopies were performed. The mean age of the patients was 53 ± 13.8 years; 50.8% of women were menopausal, 17.8% were nulliparous, and 68.7% had a previous vaginal delivery. A total of 42.6% of women were submitted to an operative hysteroscopy. Tolerance was categorized as terrible or poor in 14.9% of hysteroscopies and moderate, good, or excellent in 85.1%. A terrible or poor tolerance was more frequently reported in menopausal women (18.1% vs. 11.7% in premenopausal women, p = 0.001) and women with no previous vaginal delivery (18.8% vs. 12.9% in women with at least one vaginal birth, p = 0.007). Low tolerance led more often to scheduling a second hysteroscopic procedure under anesthesia (56.4% vs. 17.5% in reasonable-to-excellent tolerance, p < 0.0005).
Conclusion Office hysteroscopy was a well-tolerated procedure in our experience, but menopause and lack of previous vaginal delivery were associated with low tolerance. These patients are more likely to benefit from pain relief measures during office hysteroscopy.
Tagasaste silvopastures in steep-hill country. 1. Tagasaste edible dry-matter production and nutritive value
Authors: Tozer Katherine , Douglas Grant , Noakes Emma , Greenfield Rose , Cameron Catherine 
Published: March 2023

Context Tagasaste (Cytisus proliferus) has potential to supplement pasture production in steep-hill country and increase pasture resilience. Aims To (1) quantify production of edible dry matter (EDM) of pruned 2-year-old tagasaste shrubs and branches from unpruned 10-year-old tagasaste trees, and (2) determine the effect of proximity of the 10-year-old tagasaste trees on selected pasture species established as spaced transplants. Methods A site was established on the eastern coast of the North Island of New Zealand on steep-hill country (>20° slope). Tagasaste and pasture species production was measured over 3 years. Results Tagasaste shrubs produced an average of 2.7 kg EDM shrub−1 year−1 and a tree branch produced 129 g EDM year−1. The metabolisable energy content of tagasaste branches averaged 10.0 MJ kg EDM−1, the crude protein content ranged from 18% to 27% and neutral detergent fibre content averaged 39%. Branch diameter and length were poor predictors of EDM branch−1. There was no effect of increasing proximity to tagasaste on DM production of the resident pasture. Effects of increasing proximity to tagasaste on the growth and survival of selected pasture species are reported in a companion paper. Conclusions Edible-DM production was much greater from shrubs than tree branches and it was not possible to predict branch EDM from branch diameter or length. Implications A tagasaste silvopasture is likely to be more productive if tagasaste is managed for grazing in situ than if using mature trees for harvesting of branches for browse.
Nonlinear optical response and characteristic Raman spectra of phagraphene quantum dots
Authors: Ghosh Mainak , Nath Subhadip , Sen Sabyasachi , Jana Debnarayan 
Published: March 2023

Abstract
In the field of optoelectronics, quantum dots (QDs) have gained interest due to the easy modification of electronic properties. Subsequently, the importance of nonlinear optical (NLO) properties is increasing day by day. In this work, we have systematically analyzed the NLO properties of phagraphene QDs with different shapes and sizes, employing density functional theory (DFT). A negative value of cohesive energy and the absence of imaginary modes in the Raman spectra confirm the energetical stability of the QDs. Successful experimental realization of phagraphene nanoribbon has triggered the possibility of experimental feasibility of the QDs. Additionally, most of the QDs showcase high absorption in the UV region. Particularly, the variation of electronic bandgap and the number of delocalized π electrons in the structure control the NLO responses of materials. Both the electronic bandgap and the number of π electrons in the system can be tuned easily by varying the shapes and sizes of the phagraphene QDs. Both static and dynamical variations of polarizability 〈α〉, first-order 〈β〉, and second-order hyperpolarizability 〈γ〉 are calculated here. Maximum value of 〈α〉, 〈β〉 and 〈γ〉 are observed for different QDs. The variation of NLO responses with perturbing electric fields leads to the feasibility of applications in optoelectronics.
Aerodynamic optimization analysis of the front bumper side of the vehicle
Authors: Wu Bingheng , Chen Lin , Guan Qingyun , Xiao Ling , Yuan Xiayi 
Published: March 2023

Abstract
The front bumper is the earliest part of the vehicle that is exposed to the head-on airflow, and the optimization of the front bumper side plays an extremely important role in the development of the air drag of the vehicle. In this paper, the front bumper side of a model is optimized by numerical simulation method, which greatly improves the air drag of the vehicle.
Study on the influence of aerodynamic configuration on vortex vibration of steel pipe
Authors: Huang Guo , Li Xiaojun , Xia Xiang 
Published: March 2023

Abstract
In this paper, for steel pipe members with a slenderness ratio of 120, spoilers with different numbers and spacings are arranged to test the vibration reduction effect. Wind tunnel test results show that 7 sets of spoilers with a size of 1D×0.5D can basically suppress the vibration of the steel pipe member. When the spoiler spacing is 1D~4D, the reduction of the maximum amplitude is more than 90%.
Investigation of neutral hydrogen distribution and neutral hydrogen halo mass relation based on IllustrisTNG50
Authors: Wu Yanlin 
Published: March 2023

Abstract
For the sake of investigating the observational data of the universe mass distribution using neutral hydrogen as a mass tracer, it is necessary to investigate the simulation prediction of the distribution of the neutral hydrogen. In this paper, the TNG50 is selected, which is the latest released part of IllustrisTNG project, as simulation data to study the distribution of gas and neutral hydrogen as well as the relation between the halo mass and the corresponding neutral hydrogen mass contained in each halo. The results show a tendency that most of neutral hydrogen are distributed within the halo and sub-halo structures. The neutral hydrogen halo mass relation is clearly shown and the function can be will produced by the conventional HI halo mass parameterization function. Based on the analysis, this paper fills the blank of other related works with most recent TNG50 data. These results offer a guideline for the following study about the halo model and pave a path to deeper understanding and investigating the hydrogen distribution in the cosmos.
Morphology of Broad Emission Lines from Binary Supermassive Blackholes
Authors: Xiong Hongyi , Jiang Peng 
Published: March 2023

Abstract
Accretion onto a blackhole can indue extreme radiation stimulating emission lines in nearby gases. In the deep gravitational well, these clouds move at speeds up to 10,000 km/s, and so broadens the emission lines via the relativistic Doppler Effect. These broad emission lines on spectra are the most prominent feature of AGNs. The region around central black hole, where such broad emission lines are produced, is known as the broad-line region (BLR). We developed a self-consistent model to describe both the geometry of the BLR and the dynamics of the gas clouds in the BLR. The motion of clouds is described by a series of Keplerian orbits. The spectral shift of emission line can be derived by the radial velocity at each point in Keplerian orbits. Assuming that the BLR is stable, that is, the structure and distribution of gas in BLR doesn’t change over a considerable period of time, the accumulated emission line profile can be constructed by simple addition of all Keplerian orbits in the BLR. By comparing the calculated profiles to spectra observed in SDSS (Sloan Digital Sky Survey), we found that our model can satisfactorily match most observed profiles. We attempted to review and summarize potential binary AGNs. We applied the model to the study of binary AGNs and their profiles of emission lines. We considered the velocity offset due to mutual Keplerian motion of black holes in binary and added their respective profiles to produce the final, resulting emission line profile from binary AGNs. Three kinds of emission line profiles are featured in our simulations: twin-peak structures where two strong broad-lines are present; sub-peak structures where a smaller but still visible emission line accompanies the dominant line; single broad emission peak but with significant velocity offset from the systematic redshift that is derived from the narrow emission-lines on the same spectrum. We then analyzed 1,348 AGN spectra with high S/N ratio in SDSS database, and selected 26 as candidate binary supermassive blackhole systems. These candidates are valuable for following-up observation, their binary nature could be confirmed by detecting the profile variation due to orbital motions.
The wave-particle interactions between chorus waves and electrons in the Earth radiation belts
Authors: Wang Yijia 
Published: March 2023

Abstract
There exists a large number of high-energy electrons and various plasma waves in the Earth’s radiation belts. The chorus waves, as a kind of whistler-mode waves can cause electrons acceleration and loss by wave-particle interactions, thus playing a vital role in the dynamic evolution of the radiation belts. To improve our understandings of such mechanisms and facilitate people to anticipate the dramatic variation of space environment, we utilized the wave and field data from Van Allen Probes to statistically study the acceleration and loss timescale of electrons by chorus waves. The first part in this paper presents the temporal-spatial distribution of the chorus characteristics and background field parameters. The second part exhibits the loss and acceleration timescales of electrons caused by chorus waves. The main results in this paper includes: As geomagnetic activity and L shells increase, the pitch angle and momentum diffusion of electrons driven by chorus waves strengthens. The dramatic acceleration of electrons by chorus waves exists in the region with lower fpe
/fce
. Compared with keV electrons, MeV electrons are hard to be scattered by chorus waves, and electrons be precipitated into the atmosphere within several hours during highly disturbed times.
An investigation of flow characteristics between different mediums
Authors: Wang Zihan , Yi Yulong , Yin Siyuan 
Published: March 2023

Abstract
In this research topic, two-dimensional tunnels made of different mediums (including the contrast of gas-solid condition and solid-solid condition and the contrast of solid-solid condition with or without a bump) are designed to compare how they influence the velocity and the pressure of the fluid when the fluid is flowing through them. The Navier-Stokes momentum equation is used to guide the project and set up the equations of motion for these models. At the same time, Newton’s law of viscosity is applied to set the boundary conditions. Numerical methods involving finite differences are used to help discretize those equations and simulate the models in computers. The result shows that the velocity and the pressure of the fluid are influenced significantly by different tunnels settings. A nozzle with or without a bump can also significantly affect the velocity and pressure of the fluid. As the materials of tunnels change, the dependence of these flow characteristics in terms of x and y-direction will change, and the shape of the tunnel will also influence these traits.
Research on wind direction measurement of wind turbine based on fluid simulation
Authors: Ren Na , Zhu Guangwei , Fu Shaonan , He Xiaocong , Hu Jianbin , Zhu Yangguang 
Published: March 2023

Abstract
For horizontal-axis wind turbines, wind turbines typically alignment nacelle to the wind using yaw system, realizing max energy capture. If the wind turbine’s nacelle has a large error to the wind, the captured wind energy loss will be large, and it will also cause an increase in the load of the unit, which will pose a major risk to the safety of the wind turbine. Affecting the wind measurement error in addition to the performance of the sensor itself, the installation position of the wind measurement equipment also accounts for an important factor, this paper on the basis of the calculation of fluid dynamics simulation results, through the lateral and longitudinal comparison of the simulation results, pointed out the best installation location of the wind direction sensor, optimize the loss caused by wind measurement error of wind turbine in design, and provide guidance for the installation of the wind direction sensor on site.
Analysis of fluid excited noise characteristics of bulkhead opening of an Underwater Unmanned Vehicle
Authors: Wu Zhengjiang , Xiang Chao , Hu Junhua , Zeng Baoping 
Published: March 2023

Abstract
Acoustic stealth performance is an important performance index of Underwater Unmanned Aerial Vehicles. Due to equipment installation and other reasons, there will be a sea port on the bulkhead of the aircraft. Because the sea port destroys the flow field on the surface of the aircraft and produces noise, which affects the underwater communication of the aircraft. In this paper, the numerical simulation method is used to analyze the flow induced noise characteristics of the bulkhead of an underwater unmanned vehicle, and the main noise frequency characteristics at the bulkhead of the estuary are obtained, which provides data reference for the structural design of the estuary and the layout of the underwater communication system.