bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN HUKUM DAN AKIBAT KEGAGALAN HASIL KESEPAKATAN DALAM PELAYANAN REPRODUKSI MELALUI TEKNOLOGI BAYI TABUNG
Authors: Yogasara Namira Fadhya , Komalawati Veronica , Putri Sherly Ayuna 
Published: April 2023

Pelayanan reproduksi melalui teknologi bayi tabung merupakan salah satu bentuk pelayanan kedokteran berupa pemberian pembantuan dokter dalam membantu pasangan suami istri yang sulit memiliki keturunan karena ketidaksuburan (infertilitas). Hubungan hukum antara dokter dan pasien merupakan jenis perikatan inspanningverbintenis, sehingga apabila terjadi suatu kegagalan dalam mencapai hasil maka tidak dapat dituntut berdasarkan suatu hubungan kontraktual. Namun, pada kenyataannya timbul permasalahan dari hasil yang tidak sesuai dengan apa yang diinginkan sehingga menimbulkan gugatan wanprestasi. Penelitian ini bertujuan untuk menentukan dan merumuskan terjadinya hubungan hukum dan akibatnya apabila terjadi kegagalan dalam pelaksanaan pelayanan reproduksi melalui teknologi bayi tabung ditinjau dari Buku III KUHPerdata tentang Perikatan dan Undang-Undang No. 29 Tahun 2004 tentang Praktik Kedokteran.Hasil penelitian menunjukan bahwa hubungan hukum terjadi dalam pelaksanaan pelayanan reproduksi melalui teknologi bayi tabung apabila adanya kesepakatan yang dituangkan melalui informed consent (persetujuan didasarkan informasi sebelumnya), tindakan medik yang dilakukan dalam pelayanan reproduksi melalui teknologi bayi tabung meliputi fase pra tindakan, tindakan dan pasca tindakan. Didasarkan hukum perikatan, hubungan hukum antara dokter dan pasien dikategorikan sebagai jenis perikatan inspanningverbintenis sehingga apabila terjadi kegagalan dalam mencapai hasil yang disepakati pada pelayanan reproduksi melalui teknologi bayi tabung, maka akibat hukumnya tidak bisa dilaksanakan karena dokter hanya memiliki kewajiban inspanningverbintenis yaitu terpenuhinya usaha maksimal (ikhtiar) dengan hasil dari usaha tersebut tidak dapat dipastikan dan tidak dapat dikategorikan sebagai perbuatan Wanprestasi. Tetapi apabila terjadi kerugian pada pasien, pasien dapat menuntut ganti kerugian dengan membuktikan adanya kesalahan atau kelalaian dokter dalam menjalankan kewajiban hukumnya.
Bcl-2/BCL2L12 mediated apoptosis and cell cycle arrest induced by Kaempferol through the suppression of PI3K/AKT signaling pathway in Hepatocellular carcinoma
Authors: Maheshkumar Kannan  , Sridharan Jayamohan  , Ajayakumar Kulavarambil Mohanakumar  , Rajesh Kannan Moorthy  , Krishna Murthy Purushothama  , Antony Joseph Velanganni Arockiam  
Published: April 2023

Hepatocellular carcinoma (HCC) is a highly aggressive and third leading cancer-related death. PI3k/AKT and p53 signaling pathways play a vital role and regulate cellular proliferation, migration, cell cycle, apoptosis, and autophagy during cancer conditions. BCL2L12 is a bcl-2 family protein and encoded by the BCL2L12 gene, which is involved in the execution phase of apoptosis. However, the biological function of PI3K/AKT/Bcl-2 mediated BCL2L12, and its molecular mechanism in HCC is largely unknown. Herein, we investigated the effect of Kaempferol, on PI3K/AKT/Bcl-2/BCL2L12 expressions in HCC cells. The expression level of PI3K/AKT/Bcl-2/BCL2L12, and its target genes in polyphenolic flavonoid Kaempferol treated HCC cells analyzed by Quantitative Real-Time PCR and Western blotting. Subsequently, the effect of Kaempferol in HCC chemosensitivity, cell proliferation, migration, cell cycle, and apoptosis were analyzed using AO/EtBr staining, ROS staining, mitochondrial membrane potential assay, wound healing assay, Transwell migration assay, MTT assay, and PI Staining. We found that the downregulation of PI3-K, AKT, LC3A/B, MMP9, Bcl-2, and BCL2L12 and upregulation of PTEN, p53, p21, and caspase 3 in Kaempferol treated HCC cells. Subsequently, we observed that Kaempferol effectively inhibits cellular proliferation, migration and enhances apoptosis, cell cycle arrest, autophagy, and 5-Fluorouracil mediated chemosensitivity in HCC cells. Furthermore, Kaempferol has dominant role against HCC and inhibits 50-60% of cells after 24h treatment with 30μM in HepG2 and 40μM in Huh7 cells. Therefore, Kaempferol plays a promising role in cancer therapeutics by inhibiting PI3K/AKT/Bcl-2 mediated BCL2L12 expression in HCC.
СОВЕТ ҲОКИМИЯТИНИНГ ЎЗБЕКИСТОН ССРГА ХАЛҚЛАРНИ МАЖБУРИЙ КЎЧИРИШ СИЁСАТИ ТАРИХШУНОСЛИГИ
Authors: Рахманова Мавлуда 
Published: April 2023

Ушбу мақолада Иккинчи жаҳон уруши арафаси ва уруш йилларида Ўзбекистон ССРга мажбуран кўчирилган халқлар тарихини акс эттирувчи илмий адабиётлар, тадқиқотлар, монография ва мақолалар таҳлил этилган ва уларнинг Ўзбекистон тарихшунослигидаги муҳим жиҳатлари тадқиқ этилган.
ЦИВИЛИЗАЦИЯ ТУШУНЧАСИ ВА УНИНГ ГНОСЕОЛОГИК МОҲИЯТИ
Authors: Ҳакимов Акмалжон 
Published: April 2023

Ушбу мақолада жамият тараққиёти хусусиятлари, цивилизация тушунчаси ва унинг гносеологик моҳияти , илмий ёндашувларнинг хилма-хиллиги хусусида фикр юритилган.
ИМОМ АБУ МАНСУР МОТУРИДИЙ ВА МОТУРИДИЙЛИК ТАЪЛИМОТИ – ДУНЁ ОЛИМЛАРИ НИГОҲИДА
Authors: Адашова Махсума 
Published: April 2023

Мазкур мақолада ақида ва калом илмининг султони Имом Абу Мансур Мотуридийнинг буюк шахсияти ва илмий меросини ўрганиш бўйича дунё олимлари томонидан олиб борилган илмий фаолият натижалари ва уларнинг таҳлили бўйича маълумотлар берилади. Хусусан, туркиялик олимлар томонидан Имом Мотуридийнинг фалсафий меросини тадқиқ
LEXICAL UNITS OF THE SEMANTIC FIELD “MURDER”
Authors: Ismoilova Dilorom 
Published: April 2023

The article discusses the structural linguistics and its crucial methods which are implemented in scientific research. The field theory is considered as one of the effective methods to analyze the structural and semantic peculiarities of the language. The structure of the microfield of "murder" in the English language and the semantic features of its constituents are scrutinized in this article. Also, the synonymic, antonymic, hyper-hyponymic and graduonymic relations of the lexical units connected to this field within the field were analyzed based on the views of the field theory. In particular, the article reflects the results of research on the methodical use of lexical units included in the microfield of "murder". The author deeply analyzed the general and specific semantic features of these components.
Multiple Ambivalent Feminine Spaces in Zora Neale Hurston’s Feminine Characters
Authors: Salam Alali 
Published: April 2023

This paper focuses on Zora Neale Hurston’s exploration of feminine space and the way she viewed the African Americans in a very fragmentary way borrowing from the post- colonial theory Homi Bhabha’s concept of “third space” and from Stuart Hall’s concept of “becoming” and “positionality.” It also explores the concept of space in selected novels by Hurston, using Edward W. Soja’s and Henry Lefebvre’s idea about the multiplicity and hybridity of third space in favor of negating the plurality of space, taking it at the end to apply on gender in her chosen fiction.
Los sospechosos de siempre: grasas, azúcares y sales. Circulación y apropiación de controversias alimenticias en una cocina
Authors: Daza Caicedo Sandra 
Published: April 2023

El presente artículo discute la mirada reduccionista de la alimentación conocida en los estudios sociales de la ciencia y la tecnología como Nutricionismo la cual moviliza una visión reduccionista y funcionalista de la alimentación vinculándola a los efectos que micro y macro nutrientes tienen sobre la salud. Esta forma de comprender la alimentación es ampliamente utilizada en políticas nutricionales y de salud pública y movilizada por las industrias alimenticias para el desarrollo de productos “saludables”. Utilizando el ejemplo de las atribuciones sobre la salud que se les ha otorgado a las grasas, la sal y el azúcar (los sospechosos de siempre) se analiza cómo dichas atribuciones son productos de controversias y ensamblajes complejos entre laboratorios científicos, políticas e industrias alimenticias. Adicionalmente se discute a través de un análisis etnográfico en clases de cocina cómo los discursos ensamblados sobre estos tres sospechosos circulan y son traducidos y apropiados por profesores y estudiantes de estas clases relevando a estos productos y a la alimentación como un fenómeno más complejo.
IMPACT DE LA RUPTURE DES STOCKS DES PRODUITS BRASSICOLES SUR LE COMPORTEMENT DES CLIENTS DANS UN SYSTEME CONCURENCIEL DANS LA VILLE DE GOMA. CAS DE LA BRALIMA SARL DE JANVIER 2012 A OCTOBRE 2014
Authors: Micky KAFUMBAMIRA BAMENYIRWE Paul 
Published: April 2023

Ce travail traite de l’impact de la rupture de stocks des produits brassicoles sur le comportement des clients dans un système concurrentiel cas de la BRALIMA SARL/ Dépôt de Goma.
Le problème trouvé était de savoir qu’est-ce qui est à la base des ruptures des stocks des produits BRALIMA sur le marché de la ville, d’où ma question posée : quel est l’impact de la rupture des stocks des produits brassicoles sur le comportement de ses clients ? on a émis comme hypothèse : la rupture des stocks des produits brassicoles aurait un impact négatif sur le comportement de ses clients.
L’objet assigné à ce travail était d’évaluer l’impact de la rupture des stocks de BRALIMA SARL/Goma dans l’optique logistique. J’ai eu comme résultats :
A la question de savoir les causes de ruptures des stocks des produits brassicoles de la BRALIMA SARL Dépôt de Goma 70% des enquêtés sur l’assemble affirment connaitre les causes de ruptures de stocks et occupe la 1ère position, 17% des enquêtés nient connaitre les causes de ruptures de stocks des produit et 17% ont répondu je ne sais pas. On a confirmé l’hypothèse nulle.
A la question de savoir les conséquences y afférentes, les résultats de nos recherches ont poussé à confirmer l’hypothèse nulle.
En fin, à la question de proposer des pistes de solution, la comparaison du Khi carré a infirmé l’hypothèse nulle car le Khi carré existant entre les valeurs dépendantes et indépendantes ayant donné 2,9 supérieurs au Khi carré tabulaire.
SAÚDE MENTAL NO ENSINO SUPERIOR: REVISÃO DE LITERATURA
Authors: Lima Vivian Daniele de , Meira Costa Ailana Garcia , Iennaco de Vasconcelos Maria Luiza , Lourenço Lelio Moura 
Published: April 2023

A saúde mental de universitários é uma temática crescente na literatura científica, principalmente devido ao aumento da prevalência de transtornos psicológicos. Com o intuito de aprofundar aspectos como: a vulnerabilidade, fatores de risco e de proteção e consequências para a saúde dos estudantes foi realizada uma revisão de literatura das publicações dos últimos 10 anos. Elegeram-se as seguintes bases de dados: PsycInfo, Dialnet, Scielo Brasil, PePSic; e a Web of Science e analisados 161 artigos. Contatou-se que Brasil, Estados Unidos e Espanha foram os países com maior número de publicações. A metodologia adotada pela maioria das pesquisas foi a quantitativa, destacando-se delineamentos descritivos, experimentais, correlacionais e transversais. A maioria das publicações tiveram como público-alvo estudantes das áreas de saúde e verificou-se uma necessidade de validação de instrumentos específicos para o contexto acadêmico. Estudos futuros podem ampliar as discussões acerca do suicídio acadêmico e também discutir possibilidades de prevenção, propostas de intervenção e a saúde mental em estudantes de mestrado e doutorado.
Bravo Segrave!
Authors: Segrave Jeffrey 
Published: April 2023

Abstract
On March 29, 1927, Sir Henry Segrave hurtled down Florida's Daytona Beach to establish a new world land speed record of 203 mph. Two years later, Segrave returned to Daytona Beach to reclaim the land speed record for England, driving at over 231 mph. His achievements were hailed in every leading newspaper in England and the United States. This article interrogates the cultural significance of Segrave's feats and argues that Segrave personified an era intoxicated with the allure of speed and infatuated with the power of the machine. Segrave also straddled the cultural divide between the values and virtues of the Victorian era and the emergence of the new technologically sophisticated modern world. Even more significantly, Segrave stood astride a tectonic shift in the place and role of England in the postwar world.
Arsenic and Axes
Authors: Hollowak Thomas L. 
Published: April 2023

Abstract
Crime and murder, in particular, is a facet of Polonia history both misunderstood and very often overlooked. True crime stories, especially those involving murder, are among the most popular genres in popular culture. Fascination with murder is not a recent development but dates back to the beginning of journalism. For many readers, their first encounter with murder is in the pages of the daily newspaper. Between 1876 and 1925, the local press reported twenty-one murders involving Baltimore Poles as both victims and perpetrators. These real-life homicides from Baltimore's Polonia history offer an opportunity to explore how their contemporaries regarded perpetrator, victim, and the act itself. They also offer insights into the harmful impact of immigration within the Polish community. The loss of kin support networks found in the old country and poverty experienced in their new homes sometimes lead to dysfunctional families. This disorder could result in heavy drinking, juvenile delinquency, and both petty and significant crime. Murder, as the most atypical of crime, also generated more print in the local press. These case studies were selected because they were all given extensive newspaper coverage. Family reminiscences supplement the newspaper accounts. Even today, two of these murders still resonate in local folklore.
Gambaran Pelaku Riba Perspektif Al-Qur’an
Authors: Syukkur Abdul 
Published: April 2023

The Qur'an calls the perpetrator of usury like a dazed person in the afterlife, because he does not have a firm foothold, so he is unable to support his body and staggers. This kind of image of usury perpetrators is proof that usury behavior is very bad. This research provides a description of how bad the fate of usury perpetrators is in the Qur'an, by collecting verses from the Qur'an about the description of usury perpetrators, mentioning the interpretation of the mufassir, describing the whole picture and complementing it with the hadiths of the Prophet Muhammad SAW. The conclusion of this study gets the idea that the perpetrator of usury will not rise from his grave at the end of the world, other than to exist in a state like a strangled madman, and another picture of punishment in the afterlife.
Keywords: Usury, Overview, Qur'an
TRANSFORMAÇÃO DIGITAL NOS PEQUENOS NEGÓCIOS: REVISÃO BIBLIOGRÁFICA BASEADA NA SCOPUS
Authors: De Oliveira Idelmárcia Dantas , Nobre Anna Cláudia dos Santos , De Oliveira Hilderline Câmara , Barreto Laís Karla da Silva , Maia Junior Júlio Mário , Figueiró Rafael de Albuquerque 
Published: April 2023

A pandemia da Covid-19 ocasionou urgência na adoção de estratégias ancoradas no uso das tecnologias digitais pelas empresas, suscitando mudanças nessas instituições. Considerando a importância das pequenas empresas no cenário global e as mudanças mencionadas, esta pesquisa pretende analisar as publicações científicas sobre a transformação digital nos pequenos negócios, indexadas na base de dados Scopus. Trata-se de estudo exploratório, bibliográfico e com abordagem quali-quantitativa, amparado na análise de 53 resumos de artigos. Os principais resultados foram: a transformação digital nos pequenos negócios é um campo pouco explorado, com aumento de publicações a partir de 2017, sendo, em sua maioria, russas ou de países europeus, nas áreas Computer Science, Business Management and Accounting e Social Sciences; publicadas em periódicos, com as palavras-chave Digital, Business, Small e Economy; A partir de análise lexicográfica dos resumos, os artigos foram agrupados nas classes Uso de tecnologias digitais, Desenvolvimento e economia digital, Elementos estruturais dos resumos e Impactos da pandemia. Observou-se lacuna na literatura da área de Administração, em função da importância da temática e do reduzido número de estudos publicados.
المواجهة الجنائية لاستخدام العملات المشفرة في تمويل الإرهاب
Authors: نور خالد 
Published: April 2023

نتيجة طبيعية للتطور التقني المتسارع ظهرت تقنية البلوك تشين Block chain، وفرضت نفسها علي ثورة التكنولوجيا في مجال المعاملات الآمنة، لاحتوائها علي قاعدة بيانات لا مركزية مكونه من مجموعة من الكتل المترابطة والمتسلسلة والمشفرة تحتوي بداخلها علي بيانات ومعلومات يصعب اختراقها . وبرز ما يسمي بالعملات المُشفرة، وعلي رأسها البيتكوين Bitcoin كأول تطبيق عملي لاستخدام تقنية البلوك تشين، عام 2008 علي يد المخترع الياباني ساتوشي ناكاموتو. وكأي جديد لم تحمل العملات المُشفرة في طياتها ميزات إيجابية فقط، لكنها أفرزت بعض المساوئ أهمها استعمالها بشكل غير مشروع لغرض ارتكاب بعض الجرائم، كتمويل الإرهاب، إذ أن التقنية المتبعة في التعامل بتلك العملات تخفى الهوية الحقيقية للدافع والمتلقي وراء رمز رقمي. ولذلك فتعُد العملات المُشفرة من أبرز التحديات المعاصرة التي تواجه الأمن القومي، فهذه الجرائم لها آثار ضارة تطال كافة جوانب الحياة الاقتصادية والاجتماعية والسياسية والأمنية، لاعتماد التنظيمات الإرهابية عليها في عمليات التمويل والدعم والتدريب والاستقطاب والتنفيذ، والتي قد تمثل ممراً خلفياً للتمويل بعيداً عن أعين الرقابة ورصد التدفقات المالية عبر البنوك المركزية ، بعد أن قوضت الدولة عمليات التمويل التقليدية للإرهاب والجرائم المنظمة عموماً. ومن أجل ذلك كله أصبح الأمر يتطلب ضرورة وضع تشريعات قانونية وخطط استراتيجية جديدة تتضمن فكراً قانونياً وأمنياً وأساليب مغايرة لتلك الاستراتيجيات التي كانت توضع لمواجهة الجرائم التقليدية مع الاستعانة بكل ما توصل إليه البحث العلمي في هذا المجال التقني وتهيئة المناخ المناسب لتحقيق أكبر فائدة من تطبيق هذه الاستراتيجيات، للتصدي لظاهرة تداول العملات المُشفرة بطريقة غير مشروعة. ولذلك فتشمل خطة الدراسة بحث دور العملات المُشفرة في تمويل الإرهاب.
المراقبة الإلكترونية كبديل عن الحبس الاحتياطي
Authors: المنشاوي محمد 
Published: April 2023

يعتبر الحبس الاحتياطي أحد أهم الإجراءات في سير الدعوى الجنائية، وتضع التشريعات الإجرائية قيوداً على هذا الإجراء، نظراً لخطورته فتقيده بعدد من القيود، ويتشدد المشرع في هذه القيود أكثر مما عداها المقررة في إجراءات التحقيق الأخرى كونه أكثر إجراءات التحقيق إيلاما. يمثل الوضع تحت المراقبة الإلكترونية أحد أساليب السياسة الجنائية المستحدثة للحد من أضرار الحبس الاحتياطي، والاستفادة من معطيات التكنولوجيا الحديثة، حيث أثبتت التجربة العديد من المزايا التي يمكن أن تحققها المراقبة الإلكترونية من الناحية الاجتماعية والصحية والاقتصادية. وهي نظام يمكن أن تتعدد صوره وتطبيقاته ويفرض على المتهم من الالتزامات ما يحقق في الكثير من الحالات الغاية المرجوة من الحبس الاحتياطي ولا ينطوي على أي من مساوئه، ويقوم هذا النظام على السماح للمتهم بالبقاء خارج دور الحبس الاحتياطي، مع الحد من تحركاته ومراقبته بواسطة جهاز أو سوار مثبت في معصمه أو في أسفل قدمه ويتم ضبط معلوماته ومراقبته إلكترونيا من قبل جهات التحقيق أو الجهة القضائية المختصة. وتأتي ضرورة الاهتمام بالمراقبة الإلكترونية كبديل عن الحبس الاحتياطي، نظرا لأن كل المؤشرات توضح اتجاه أعداد المجبوسين احتياطيا للزيادة عالميا، الأمر الذي استدعى المشرع البحث عن أليات ووسائل مستحدثة لمحاولة الحد من تضخم الحبس الاحتياطي.
Investigating the impacts of connected and automated vehicles on road carbon emissions: A semi-systematic literature review
Authors: Toliyat Seyed Mohammad Hossein , Remfry Catherine , Levi Isaac 
Published: April 2023

Rapid development of Connected and Automated Vehicles (CAVs) besides the urgency of cutting down carbon emissions in the next three decades raise a question about the impact of CAVs deployment on carbon emissions from transport sector. The uncertainties around this question are grave due to the complex interactions between technological capabilities, policy interventions and public travel behaviour. Previous modelling and simulation studies suggest a wide variation in how CAVs may contribute to carbon saving strategies or worsen CO2 emissions. This indicates a necessity for breaking the technology down into the mechanisms as well as features that directly or indirectly affect emissions at vehicular and/or network levels.
This paper aims to investigate the mechanisms and different ways that CAVs may decrease or increase road carbon emissions in order to constrain the uncertainties. A semi-systematic literature review was designed and conducted which resulted in identification of 40 relevant publications and documents. Subsequently, 38 levers were ascertained and classified across five major categories: i) emissions per mile; ii) emissions per vehicle; iii) emissions from infrastructure; iv) vehicle miles travelled (VMT); and v) emissions per manufactured vehicle.
The estimates for potential impacts of the most significant levers on key performance indicators (KPIs) such as VMT, vehicle occupancy rate and number of manufactured vehicles are provided. Some of the plausible policy interventions are discussed. The findings are also closely related to energy consumption (other than carbon emissions). Therefore, the results can be used for studying potential implications for mass adoption of automated and electric vehicles (AEVs).
Tibial avascular necrosis in a trimalleolar ankle fracture
Authors: Renier Edee , Powell Eric 
Published: April 2023

Fractures involving the distal tibia and fibula are challenging to treat, and can have debilitating sequelae. While many fractures can be treated conservatively, open reduction with internal fixation for displaced or unstable variants is the standard of care. Complications in treatment of these complex fractures are relatively common and often unavoidable. The authors present the case study of a 49 year-old female who underwent open reduction with internal fixation of a closed Danis Weber type-B trimalleolar ankle fracture and suffered avascular necrosis of the anterior lateral tibial plafond. This patient underwent successful trimalleolar ankle fracture fixation surgery, and subsequently suffered collapse of the anterior lateral aspect of the tibia 14 weeks following her index procedure. This case study lends an example of avascular necrosis causing devastating osseous collapse despite timely and robust fracture fixation.
Feedback and winning-losing probability effects on economic behavior in risky choices decision-making
Authors: Pérez-Acosta Andrés M. , Farina Rafael , Valle Mauricio A. , Oliveira Bueno José Lino 
Published: April 2023

Myopic Loss Aversion (MLA) is one of the study objects of behavioral economics. It corresponds to the fact that participants, when facing choice situations, cannot rationally evaluate the risks and profits of available options, leading them to choose investments more likely to occur but less profitable. This behavior shows that they cannot evaluate the options satisfactorily, so they have sub-optimal decisions. There may be conditions for MLA more favorable for it to occur, as the frequency one shows the participant the outcomes of their choices (feedback) and the probability of winning or losing. In this way, this study aims to evaluate how feedback influences participants' choices and the influence and interaction of the winning and losing probability. This study had the participation of 80 people, ages 18 to 30 years, all university students, 29 women and 51 men, without either relation to business degree courses or familiarity with the research area on economic behavior. The experiment consisted in making nine repeated choices in a lottery game. Participants started the experiment with R$1000 (a thousand) fictitious reais (Brazilian currency); each lottery game had a cost of 150 reais, and the profits returned this invested value with an addition of more 150 reais. The results indicate that the presence of feedback induces participants to bet more. However, the winning and losing probability do not influence the invested amount, and there was no interaction between these two factors.