bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Legal Position Of Marriage Through a Unified Marriage Isbat Trial At The Gorontalo Religious Court
Authors: Lamara Aneng T. 
Published: August 2023

Abstract: The purpose of writing to be achieved is to know and analyze about what is the legal status of the wife who is still bound by a legal marriage in applying for marriage confirmation through a unified marriage isbattrial? and What are the legal implications for the legal status of the wife due to the establishment of the confirmation of marriage through a unified marriage isbat trial? This study uses a type of Normative research with two approaches, namely the legislative approach and the case approach. the results showed that: First, the position of the legal status of the wife who is still bound by a legal marriage in filing a marriage confirmation through a juridically integrated marriage isbat trial has violated the provisions contained in the marriage law that expressly does not allow for the wife to marry twice before there is a divorce ruling that has permanent legal force from the Court. Second, the legal implications arising from the legal status of the wife due to the establishment of the legalization of marriage through a unified marriage isbat trial, namely the emergence of legality for legally valid wives due to not getting a divorce ruling from the Court on the previous marriage which is essentially contrary to the provisions of the marriage law on the prohibition of polyandry for the wife and opens the space for violations of the law. from the legal side of state administration through legal smuggling at the time of issuance of marriage books. Keywords: Marriage Isbat; Ratification; Court.
Assessing The Authority Of The Village Head Of Buba'a District Of Boalemo Regency Beach District In The Appointment And Dismissal Of Village Devices
Authors: Harun Ismet 
Published: August 2023

The purpose of this study is to find out how the role of the Village Consultative Agency in supervising the performance of the village head in Buba'a village of Paguyaman Pantai Subdistrict and knowing what factors hinder the supervision of village performance in Buba'a village of Paguyaman Pantai Subdistrict. This research uses normative-empirical research methods with descriptive data analysis techniques with more descriptions of interview results, observations, and documentation studies. The results of this study show that first, the authority of the head of Buba'a Village, Boalemo District Beach District in the appointment and dismissal of village devices has not been by the applicable rules, where for almost three years running in the appointment of village devices recruiting outside communities. This is certainly not by what is mandated by Law No. 6 of 2014 concerning villages. In addition, in the appointment or dismissal of Buba'a Village devices, there is no communication between the village head or the local cat. Second, the factors that hinder the performance of the head of Buba'a Village in the appointment and dismissal of village devices are (1) Factors from within the head of Buba'a Village itself because he ignores the applicable rules; (2) The outside factor as a supporter of the performance of the village head is the function of BPD in monitoring the performance of the village head has not been effective; (3) There is no good 2-way communication between the village chief of Buba'a and the local cat in terms of the appointment and dismissal of village devices.
Cita Rasa Penegakan Hukum Terhadap Penggunaan Senjata Tajam Oleh Anak Dibawah Umur
Authors: Repi Aljoshua J.T 
Published: August 2023

Perlu penanganan secara tepat terhadap anak dibawah umur yang melakukan berbagai bentuk tindak pidana berupa membawa dan menggunakan senjata tajam termasuk dalam hal penegakan hukumnya, maka kajian yang dilakukan dalam penelitian ini bertujuan untuk menjelaskan faktor-faktor anak melakukan tindak pidana dengan menggunakan senjata tajam serta peran kepolisian dalam menegakan hukum terhadap anak sebagai pelaku tindak pidana. Metode penelitian yang digunakan dalam penelitian ini adalah penelitian empiris dengan pendekatan lapangan dan perundang-undangan, serta teknik pengumpulan data secara kepustakaanditunjang dengan data wawancara. Dalam penelitian ini teknik analisis yang digunakan adalah deskriptif kualitatif. Berdasarkan hasil penelitian maka dapat disimpulkan bawah, motivasi-motivasi (faktor) anak menggunakan senjata tajam dalam tindak pidana diantaranya; (1) Motivasi Intrinsik, dan (2) Motivasi Ekstrinsik yang terdiri dari, Faktor keluarga, Faktor pendidikan dan sekolah, serta Faktor pergaulan anak, Faktor media sosial. Adapun Peran kepolisian Polres Gorontalo Kota dalam menangani anak-anak yang menggunakan senjata tajam tapi belum pada tindakan kejahatan, masih akan diberikan nasihat terlebih dahulu dan dikembalikan kepada orangtua mereka. Jika anak tersebut sudah berbuat tindakan kriminal untuk kesekian kalinya, maka pihak kepolisian akan melaksanakan proses penegakan hukum sebagaimana regulasi yang telah ada berdasarkan Undang-Undang Nomor 11 Tahun 2012 Tentang Sistem Peradilan Pidana Anak, namun dalam hal kejahatan yang dilakukan merupakan kejahatan senjata tajam dengan ancaman hukuman diatas 7 (tujuh) tahun penjara.
Act Of Settlement By Investigators Against Alleged Adultery
Authors: Haris Rifki Wahyudi 
Published: August 2023

Abstract: This study aims to determine the resolution by investigators to the alleged adultery. The method used in this study is an empirical or sociological research methodology. This study used a qualitative approach and sampling using Purposive Sampling and used descriptive analysis techniques. The results of this study show that the settlement of suspected criminal acts of adultery in the jurisdiction of the Gorontalo Police is carried out with Preventive Efforts, namely socialization or counseling in each village and village. Then the Gorontalo Police often patrols to order or prevent acts prohibited by law including adultery behavior and the form of repressive efforts carried out by the police or investigators of the Gorontalo Police is through investigations, arrests, investigations, until it reaches the judiciary which is then decided by the judge. The repressive efforts made by the police are based on the preliminary evidence that exists because this adultery case is a complaint that can certainly be dismissed because of the party being harmed or caught by Tanagan. Investigators must be more courageous in providing stricter and more straightforward law enforcement in terms of cracking down on the crime of prostitution or in other words adultery.
Fulfillment of The Constitutional Rights of Abandoned Children Victims of Economic Exploitation
Authors: Achir Nuvazria 
Published: August 2023

The existence of abandoned children who are victims of economic exploitation in Gorontalo City is very concerning, because there are many cases related to violence and unfulfilled guarantees of human rights to children. This study aims to find out how to fulfill the constitutional rights of abandoned children as victims of economic exploitation and its inhibiting factors in the city of Gorontalo. The research method uses a case approach and is analyzed qualitatively, data collection through observation, interviews and documentation. The results showed that the fulfillment of children's rights in Gorontalo city was carried out through assessment efforts, cooperation in regional apparatus organizations (OPD), the implementation of raids and interventions, the provision of protection cars (Molin) and mobile motorcycles (Torling) as well as the use of shelter facilities. Factors Hindering the fulfillment of rights include the Economic Difficulties of Parents, Education to children and families has not been sufficiently helpful, because the reasons for carrying out economic activities on their own desires and the demands of needs.
Attainment of Gender Equity and Social Justice for Nigerian Women Through the Implementation of CEDAW’S Right to Choose: an Initiative for the Development of Nigeria
Authors: Olatokun Ganiat Mobolaji 
Published: August 2023

The Convention on the Elimination of all forms of Discrimination against Women (CEDAW) is yet to be domesticated and implemented in Nigeria. Hence, its provisions, particularly, Article 16(1) (e) which provided inter alia that, men and women should be given the same right to decide freely and responsibly on the number and spacing of their children, cannot be given effect to. Hence, when it comes to deciding on the number and spacing of children, women in Nigeria are not given any say. This is in contradiction to social justice for women. This equally shows the inequality status of women to men in Nigeria. In order for Nigerian women to enjoy the dividend of gender equality and have access to justice, the attitude of Nigerian men (mostly the uneducated ones, and even some educated ones) of turning their wives into child producing machines must be stopped. Most women in Nigeria are faced with problem of having children yearly in order satisfy their husbands. These women, despite being exposed to health challenges associated with several child births, are usually trapped in a difficult position either to continue production of babies, or to let go their husbands to take another wife. Most women in Nigeria opt for the later. However, it has been viewed by this researcher that if allowed to prosper, the provision of fairness and justice in the distribution of benefits and responsibilities between men and women is well covered by CEDAW’s right to choose which is well captured under its Article 16. This is a doctrinal research which utilizes the use of books, journals and internet sources for research. The research concluded that future development based on analysis suggests the full implementation of CEDAW’s provision under Article 16.
Exploring the shared molecular mechanisms between systemic lupus erythematosus and primary Sjögren’s syndrome based on integrated bioinformatics and single-cell RNA-seq analysis
Authors: Cui Yanling , Zhang Huina , Wang Zhen , Gong Bangdong , Al-Ward Hisham , Deng Yaxuan , Fan Orion , Wang Junbang , Zhu Wenmin , Sun Yi Eve 
Published: August 2023

BackgroundSystemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are common systemic autoimmune diseases that share a wide range of clinical manifestations and serological features. This study investigates genes, signaling pathways, and transcription factors (TFs) shared between SLE and pSS.MethodsGene expression profiles of SLE and pSS were obtained from the Gene Expression Omnibus (GEO). Weighted gene co-expression network analysis (WGCNA) and differentially expressed gene (DEG) analysis were conducted to identify shared genes related to SLE and pSS. Overlapping genes were then subject to Gene Ontology (GO) and protein-protein interaction (PPI) network analyses. Cytoscape plugins cytoHubba and iRegulon were subsequently used to screen shared hub genes and predict TFs. In addition, gene set variation analysis (GSVA) and CIBERSORTx were used to calculate the correlations between hub genes and immune cells as well as related pathways. To confirm these results, hub genes and TFs were verified in microarray and single-cell RNA sequencing (scRNA-seq) datasets.ResultsFollowing WGCNA and limma analysis, 152 shared genes were identified. These genes were involved in interferon (IFN) response and cytokine-mediated signaling pathway. Moreover, we screened six shared genes, namely IFI44L, ISG15, IFIT1, USP18, RSAD2 and ITGB2, out of which three genes, namely IFI44L, ISG15 and ITGB2 were found to be highly expressed in both microarray and scRNA-seq datasets. IFN response and ITGB2 signaling pathway were identified as potentially relevant pathways. In addition, STAT1 and IRF7 were identified as common TFs in both diseases.ConclusionThis study revealed IFI44L, ISG15 and ITGB2 as the shared genes and identified STAT1 and IRF7 as the common TFs of SLE and pSS. Notably, the IFN response and ITGB2 signaling pathway played vital roles in both diseases. Our study revealed common pathogenetic characteristics of SLE and pSS. The particular roles of these pivotal genes and mutually overlapping pathways may provide a basis for further mechanistic research.
Comparison of propofol-esketamine versus propofol for anesthesia in gastroscopy: a double-blind, randomized controlled clinical trial
Authors: Liu Xiaoli , Xiao Qingyu , Zhuang Shaohui 
Published: August 2023

ObjectiveTo compare the effects of propofol-esketamine and propofol in gastroscopy in adults.MethodsThis randomized controlled clinical trial was performed from January 2021 to March 2021. Eighty patients were enrolled and allocated into normal saline group (group N) and esketamine group (group E). The primary outcome was total amount of propofol. Secondary outcomes included incidences of injection pain, involuntary movement, hemodynamic and respiratory adverse events during examination, total examination time, recovery time and postoperative adverse effects.ResultsTotal amount of propofol was significantly smaller in group E (101.64 ± 32.64 mg) than in group N (129.55 ± 36.34 mg, p = 0.001). Incidences of injection pain, involuntary movement and hypotension was significantly lower in group E than in group N. Incidences of hypertension and tachycardia was higher in group E than in group N. There was no significant difference in incidences of laryngospasm or hypoxemia, total examination time, recovery time, incidences of postoperative adverse effects between two groups.ConclusionCombination of propofol with 0.2 mg/kg esketamine reduced total amount of propofol, provided a more stable hemodynamic status and did not affect recovery time in gastroscopy.Clinical trial registrationhttp://www.chictr.org, identifier ChiCTR2100042406.
Metabolic fingerprinting of systemic sclerosis: a systematic review
Authors: Morales-González Victoria , Galeano-Sánchez Daniel , Covaleda-Vargas Jaime Enrique , Rodriguez Yhojan , Monsalve Diana M. , Pardo-Rodriguez Daniel , Cala Mónica P. , Acosta-Ampudia Yeny , Ramírez-Santana Carolina 
Published: August 2023

Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease, marked by an unpredictable course, high morbidity, and increased mortality risk that occurs especially in the diffuse and rapidly progressive forms of the disease, characterized by fibrosis of the skin and internal organs and endothelial dysfunction. Recent studies suggest that the identification of altered metabolic pathways may play a key role in understanding the pathophysiology of the disease. Therefore, metabolomics might be pivotal in a better understanding of these pathogenic mechanisms.Methods: Through a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA), searches were done in the PubMed, EMBASE, Web of Science, and Scopus databases from 2000 to September 2022. Three researchers independently reviewed the literature and extracted the data based on predefined inclusion and exclusion criteria.Results: Of the screened studies, 26 fulfilled the inclusion criteria. A total of 151 metabolites were differentially distributed between SSc patients and healthy controls (HC). The main deregulated metabolites were those derived from amino acids, specifically homocysteine (Hcy), proline, alpha-N-phenylacetyl-L-glutamine, glutamine, asymmetric dimethylarginine (ADMA), citrulline and ornithine, kynurenine (Kyn), and tryptophan (Trp), as well as acylcarnitines associated with long-chain fatty acids and tricarboxylic acids such as citrate and succinate. Additionally, differences in metabolic profiling between SSc subtypes were identified. The diffuse cutaneous systemic sclerosis (dcSSc) subtype showed upregulated amino acid-related pathways involved in fibrosis, endothelial dysfunction, and gut dysbiosis. Lastly, potential biomarkers were evaluated for the diagnosis of SSc, the identification of the dcSSc subtype, pulmonary arterial hypertension, and interstitial lung disease. These potential biomarkers are within amino acids, nucleotides, carboxylic acids, and carbohydrate metabolism.Discussion: The altered metabolite mechanisms identified in this study mostly point to perturbations in amino acid-related pathways, fatty acid beta-oxidation, and in the tricarboxylic acid cycle, possibly associated with inflammation, vascular damage, fibrosis, and gut dysbiosis. Further studies in targeted metabolomics are required to evaluate potential biomarkers for diagnosis, prognosis, and treatment response.
Direct training high-performance spiking neural networks for object recognition and detection
Authors: Zhang Hong , Li Yang , He Bin , Fan Xiongfei , Wang Yue , Zhang Yu 
Published: August 2023

IntroductionThe spiking neural network (SNN) is a bionic model that is energy-efficient when implemented on neuromorphic hardwares. The non-differentiability of the spiking signals and the complicated neural dynamics make direct training of high-performance SNNs a great challenge. There are numerous crucial issues to explore for the deployment of direct training SNNs, such as gradient vanishing and explosion, spiking signal decoding, and applications in upstream tasks.MethodsTo address gradient vanishing, we introduce a binary selection gate into the basic residual block and propose spiking gate (SG) ResNet to implement residual learning in SNNs. We propose two appropriate representations of the gate signal and verify that SG ResNet can overcome gradient vanishing or explosion by analyzing the gradient backpropagation. For the spiking signal decoding, a better decoding scheme than rate coding is achieved by our attention spike decoder (ASD), which dynamically assigns weights to spiking signals along the temporal, channel, and spatial dimensions.Results and discussionThe SG ResNet and ASD modules are evaluated on multiple object recognition datasets, including the static ImageNet, CIFAR-100, CIFAR-10, and neuromorphic DVS-CIFAR10 datasets. Superior accuracy is demonstrated with a tiny simulation time step of four, specifically 94.52% top-1 accuracy on CIFAR-10 and 75.64% top-1 accuracy on CIFAR-100. Spiking RetinaNet is proposed using SG ResNet as the backbone and ASD module for information decoding as the first direct-training hybrid SNN-ANN detector for RGB images. Spiking RetinaNet with a SG ResNet34 backbone achieves an mAP of 0.296 on the object detection dataset MSCOCO.
Prediction of extracapsular extension in prostate cancer using the Likert scale combined with clinical and pathological parameters
Authors: Wang Jun-guang , Huang Bin-tian , Huang Li , Zhang Xia , He Pei-pei , Chen Jun-bo 
Published: August 2023

AbstractThis study aimed to investigate the independent clinical, pathological, and radiological factors associated with extracapsular extension in radical prostatectomy specimens and to improve the accuracy of predicting extracapsular extension of prostate cancer before surgery.MethodsFrom August 2018 to June 2023, the clinical and pathological data of 229 patients with confirmed prostate cancer underwent radical prostatectomy from The Second Hospital of Yinzhou. The patients’ multiparametric magnetic resonance imaging data were graded using the Likert scale. The chi-square or independent-sample T-test was used to analyze the related factors for an extracapsular extension. Multivariate analysis was used to identify independent factors associated with extracapsular extension in prostate cancer. Additionally, receiver operating characteristic curve analysis was used to calculate the area under the curve and assess the diagnostic performance of our model. The clinical decision curve was used to analyze the clinical net income of Likert scale, biopsy positive rate, biopsy GG, and combined mode.ResultsOf the 229 patients, 52 had an extracapsular extension, and 177 did not. Multivariate analysis showed that the Likert scale score, biopsy grade group and biopsy positive rate were independent risk factors for extracapsular extension in prostate cancer. The area under the curves for the Likert scale score, biopsy grade group, and biopsy positive rate were 0.802, 0.762, and 0.796, respectively. Furthermore, there was no significant difference in the diagnostic efficiency for extracapsular extension (P&gt;0.05). However, when these three factors were combined, the diagnostic efficiency was significantly improved, and the area under the curve increased to 0.905 (P&lt;0.05). In the analysis of the decision curve, The clinical net income of the combined model is obviously higher than that of Likert scale, biopsy positive rate, and biopsy GG.ConclusionThe Likert scale, biopsy grade group and biopsy positive rate are independent risk factors for extracapsular extension in prostate cancer, and their combination can significantly improve the diagnostic efficiency for an extracapsular extension.
The effects of climate change-induced flooding on harvest failure in Burkina Faso: case study
Authors: Müller Charlotte , Ouédraogo Windpanga Aristide , Schwarz Maximilian , Barteit Sandra , Sauerborn Rainer 
Published: August 2023

BackgroundClimate change leads to more frequent and severe extreme weather events including floods, heatwaves, heavy rainfalls, and droughts. In contrast to the majority of research on weather extremes in sub-Saharan Africa, which focus primarily on how a lack of rainfall causes droughts, this paper aims to elucidate the effect of flooding on harvest failure in rural Burkina Faso.MethodsWe conducted a case study in north-western Nouna, Burkina Faso, between August and December 2021 covering a study population of n = 180 participants. The study comprised four components: (i) interviews with farmers (n = 180) on whether any of their fields had been inundated and if so, on harvest loss on these fields; (ii) determining the feasibility of using Sentinel-2 satellite images to validate study participants reports of floods; (iii) characterizing short-term weather including frequency and duration, of extreme rainfall events within the study area, as well as comparing cumulative rainfall (long-term) over the past 50 years; and (v), estimating both the food energy and economic loss of harvest failure due to flooding.Results49% of interviewed farmers (n = 88) reported that floods had damaged at least one of their fields. Some fields (n = 13, 7%) had no harvest due to flooding, while some farmers (n = 14, 8%) had lost part of their harvest. Images from the Sentinel-2-Satellite indicated that reported and remotely observed flooding were consistent. According to time series of data from the local weather station, there has been an increase irregular rainfall distribution and at the same time of cumulative annual rainfall in Nouna. Furthermore, a first illustrative calculation allowed us to estimate the amount of energy lost when one hectare of a common crop is flooded.ConclusionThis case study demonstrated that flood-related harvest failures leading to crop losses in sub-Saharan Africa, exemplified by Burkina Faso, are likely to be substantial. This study serves as a proof-of-principle for flooding effects on food security. This could provide more detail for agricultural adaptation and mitigation strategies. Inundation-vulnerable fields need alternative and novel management practices, which may only be effectively implemented if agricultural institutions and national policy-making bodies receive evidence of flooding e.g., from remote sensing.