bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRATEGI PEMASARAN SAGU DALAM MENINGKATKAN POTENSI PASAR PERSPEKTIF MANAJEMEN BISNIS SYARIAH
Authors: Sermaf Nur Jihan Fahira Hasan 
Published: January 2023

AbstrakPenelitian ini bertujuan untuk mengetahui strategi pemasaran sagu dalam meningkatkan potensi pasar ditinjau dari perspektif manajemen bisnis syariah di Dusun Hurnala Kabupaten Maluku Tengah. Jenis penilitian ini adalah penelitian kualitatif deskriptif. Pengumpulan data dilakukan dengan mengadakan observasi, wawancara, dokumentasi dan penelusuran referensi. Dari penelitian ini diperoleh hasil bahwa penerapan strategi yang digunakan oleh pengusaha sagu adalah menjadikan pasar sebagai tempat menjual usaha sagu mereka dan juga ada beberapa penjual sagu yang menggunakan media sosial sebagai tempat promosi dan karena pengetahuan dari masyarakat atau konsumen sagu banyak yang sudah mengetahui tempat goni atau rumah pengusaha sagu tersebut dari mulut ke mulut sehingga konsumen langsung membeli sagu di goni atau memesan sagu melalui telpon. Usaha sagu di Dusun Hurnala berupa tumang, sagu lempeng, dan sagu gula. Strategi pemasaran sagu perspektif bisnis syariah yang dilakukan oleh penjual sagu di Dusun Hurnala menerapkan strategi pemasaran yang mencontoh praktik pemasaran dan sifat Nabi Muhammad saw, yaitu Siddiq (jujur, benar), Amanah (Dapat Dipercaya), Fathanah (Cerdas), dan Tabligh (komunikatif).Kata kunci: Strategi, Pasar, Sagu, Pemasaran, Bisnis Syariah
Toxicity of essential oils on cabbage seedpod weevil (Ceutorhynchus obstrictus) and a model parasitoid (Nasonia vitripennis)
Authors: Sulg Silva , Kaasik Riina , Kallavus Triin , Veromann Eve 
Published: January 2023

Plant essential oils are being increasingly studied as a potential environmentally friendly alternative to synthetic insecticides. The insecticidal efficacy of essential oils on the cabbage seedpod weevil (Ceutorhynchus obstrictus), an important oilseed rape pest, has not been previously tested. We examined the impact of six essential oils on C. obstrictus via contact with dry residues on leaf and flower surfaces. We also examined the effect of these essential oils on a model non-target parasitoid wasp, Nasonia vitripennis. Exposure to dry residues of cumin (Cuminum cyminum) and cinnamon (Cinnamomum verum) essential oils (applied to oilseed rape leaves) resulted in significant loss of mortality and immobility in C. obstrictus adults. Treatment with C. cyminum essential oil at 1.5% resulted in 50.71% mortality and 87.3% combined mortality and immobility in C. obstrictus. Cinnamomum verum oil, at 1.5% concentration, resulted in 88.8% mortality and immobility among C. obstrictus 24 h post-treatment. All treatments studied with essential oil dry residues at 0.3% concentration caused high mortality and immobility in N. vitripennis. The greatest mortality and immobility were observed at 0.3% concentration in F. vulgare and C. verum treatments (54 and 53% loss respectively). At 0.1% concentration, F. vulgare and T. vulgaris significantly reduced parasitoids mobility and at 1.5% concentration all essential oils resulted in 100% mortality of N. vitripennis after 3 h. Our study revealed that C. cyminum and C. verum essential oils may have potential in the management of C. obstrictus. However, their impact on non-target organisms, including parasitoids, needs to be studied more thoroughly to determine the potential of essential oil main compounds in integrated pest management.
Design and evaluation of sodium alginate-based hydrogel dressings containing Betula utilis extract for cutaneous wound healing
Authors: Ishfaq Bushra , Khan Ikram Ullah , Khalid Syed Haroon , Asghar Sajid 
Published: January 2023

Traditional wound dressings have a limited capacity to absorb exudates, are permeable to microbes, and may adhere to wounds, which leads to secondary injuries. Hydrogels are promising alternative dressings to overcome the above challenges. In this study, we developed sodium alginate-based hydrogel films loaded with Betula utilis bark extract. These films were prepared via solvent-casting crosslinking method and evaluated for wound healing activity. Prepared films were 0.05–0.083 mm thick, flexible with folding endurance ranging from 197–203 folds, which indicates good physical properties. Optimized formulations exhibited successful loading of extract in the film matrix without any interaction as confirmed by FTIR. Maximum zone of inhibition against Gram-positive and Gram-negative bacteria was achieved by optimum formulation (B6), i.e., 19 mm and 9 mm, respectively, with &gt; 90% scavenging activity. Furthermore, this optimum formulation (B6) was able to achieve 93% wound contraction in rats. Histograms of the optimized formulation treated group also revealed complete reepithelization of wounds. Conclusively, our extract-loaded hydrogel dressing successfully demonstrated its potential for cutaneous wound healing.
The efficacy of femoral augmentation for hip fracture prevention using ceramic-based cements: A preliminary experimentally-driven finite element investigation
Authors: Fung Anita , Fleps Ingmar , Cripton Peter A. , Guy Pierre , Ferguson Stephen J. , Helgason Benedikt 
Published: January 2023

Femoral fractures due to sideways falls continue to be a major cause of concern for the elderly. Existing approaches for the prevention of these injuries have limited efficacy. Prophylactic femoral augmentation systems, particularly those involving the injection of ceramic-based bone cements, are gaining more attention as a potential alternative preventative approach. We evaluated the mechanical effectiveness of three variations of a bone cement injection pattern (basic ellipsoid, hollow ellipsoid, small ellipsoid) utilizing finite element simulations of sideways fall impacts. The basic augmentation pattern was tested with both high- and low-strength ceramic-based cements. The cement patterns were added to the finite element models (FEMs) of five cadaveric femurs, which were then subject to simulated sideways falls at seven impact velocities ranging from 1.0 m/s to 4.0 m/s. Peak impact forces and peak acetabular forces were examined, and failure was evaluated using a strain-based criterion. We found that the basic HA ellipsoid provided the highest increases in both the force at the acetabulum of the impacted femur (“acetabular force”, 55.0% ± 22.0%) and at the force plate (“impact force”, 37.4% ± 15.8%). Changing the cement to a weaker material, brushite, resulted in reduced strengthening of the femur (45.2% ± 19.4% acetabular and 30.4% ± 13.0% impact). Using a hollow version of the ellipsoid appeared to have no effect on the fracture outcome and only a minor effect on the other metrics (54.1% ± 22.3% acetabular force increase and 35.3% ± 16.0% impact force increase). However, when the outer two layers of the ellipsoid were removed (small ellipsoid), the force increases that were achieved were only 9.8% ± 5.5% acetabular force and 8.2% ± 4.1% impact force. These results demonstrate the importance of supporting the femoral neck cortex to prevent femoral fractures in a sideways fall, and provide plausible options for prophylactic femoral augmentation. As this is a preliminary study, the surgical technique, the possible effects of trabecular bone damage during the augmentation process, and the effect on the blood supply to the femoral head must be assessed further.
Diagnostic value of real-time four-dimensional transesophageal echocardiography on the implant-related thrombus
Authors: Yu Yi , Zhang Rui , Chen Yu-Han , Wang Ting , Tang Xiao-Li , Gong Chang-qi , Shao Yun , Wang Zheng , Wang Yue-Peng , Li Yi-Gang 
Published: January 2023

ObjectivesThis study aims to evaluate the diagnostic value of real-time four-dimensional transesophageal echocardiography (RT4D-TEE) for implant-related thrombus (IRT).MethodsWe collected 1,125 patients with atrial fibrillation from May 2019 to February 2022 in our hospital. All patients accepted transesophageal echocardiography (TEE) examination to exclude any thrombi before the LAAC procedure.ResultsThere were 760 patients with LAAC, 66 patients with CIED, and 299 patients without any implantations. A total of 40 patients with an established diagnosis of IRT were further analyzed. The accurate detection rate of IRT by RT4D-TEE was 4.8% (40/826), which was higher than 3.8% (31/826) by 2D-TEE (P = 0.004). No IRT was found on TEE in the rest of the 786 patients. These 40 patients were divided into LAAC (n = 23) and CIED (n = 17) groups according to the results of RT4D-TEE. In the LAAC group, IRT distributed on different parts of the LAA occluder surface, 91.3% (21/23) with clumps of thrombi, and 8.7% (2/23) with a thin layer of thrombi covering the surface of the occluder. In the CIED group, thrombi were seen attached to the leads in the right atrium and right ventricle. The thrombi were beaded in 17.6% (3/17), corded in 17.6% (3/17), and clotted in the remaining 64.7% (11/17) of cases. After adjusting the anticoagulant dosage and following up for 6 months, 20% (8/40) of cases were successfully resolved, 67.5% (27/40) became smaller, and 12.5% (5/40) showed no changes.ConclusionThe accurate detection rate of IRT by RT4D-TEE was significantly higher than that by 2D-TEE. 2D-TEE has limitations, but RT4D-TEE can be used as an effective complementary method. Imaging and some clinical features differ significantly between IRT on occluder and IRT on CIED lead.
Suture-based vs. pure plug-based vascular closure devices for VA-ECMO decannulation–A retrospective observational study
Authors: Scherer Clemens , Theiss Hans , Istrefi Mario , Binzenhöfer Leonhard , Kupka Danny , Stocker Thomas , Lüsebrink Enzo , Stambollxhiu Era , Alemic Ahmed , Petzold Tobias , Stark Konstantin , Deseive Simon , Braun Daniel , Joskowiak Dominik , Peterss Sven , Hausleiter Jörg , Hagl Christian , Massberg Steffen , Orban Martin 
Published: January 2023

BackgroundVeno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a valuable treatment option for patients in cardiogenic shock, but complications during decannulation may worsen the overall outcome. Therefore, the aim of this study was to compare the efficacy and safety of suture-based to pure plug-based vascular closure devices for VA-ECMO decannulation.MethodsIn this retrospective study, the procedural outcome of 33 patients with suture-based Perclose ProGlide closure devices was compared to 38 patients with MANTA plug-based closure devices.ResultsRate of technically correct placement of closure devices was 88% in the suture-based group and 97% in the plug-based group (p = 0.27). There was a significant reduction of severe bleeding events during VA-ECMO decannulation in plug-based versus suture-based systems (3% vs. 21%, p = 0.04). Ischemic complications occurred in 6% with suture-based and 5% with plug-based device (p = 1.00). Pseudoaneurysm formation was detected in 3% in both groups (p = 1.00). No switch to vascular surgery due to bleeding after decannulation was necessary in both groups.ConclusionBased on our retrospective analysis, we propose that plug-based vascular closure should be the preferred option for VA-ECMO decannulation. This hypothesis should be further tested in a randomized trial.
Construction technologies and mechanical effects of the pipe-jacking crossing anchor-cable group in soft stratum
Authors: Han Jianyong , Wang Jun , Jia Dongfeng , Yan Fushun , Zhao Yue , Bai Xiaoyu , Yan Nan , Yang Guang , Liu Dong 
Published: January 2023

In this study, an open-cut approach using steel-sheet piles and jet grouting piles for waterproofing was proposed to resolve the problem that ordinary pipe-jacking equipment cannot cross areas with existing anchor cables in soft stratum. The case history of a pipe-jacking project of a sewage treatment plant in the Jinan East Railway Station area was investigated. The mechanical properties of steel-sheet piles, horizontal displacement of piles, and ground surface settlement in the anchor-cable crossing area were investigated based on in situ observations. Numerical investigations were performed using the finite element method (FEM). The effects of existing anchor cables on the mechanical behaviors of retaining structures, deformation variation of the ground, and stability of the excavation were studied. The results indicate that the composite supporting structures of steel-sheet piles and jet grouting piles have a positive effect on waterproofing and deformation control in areas with existing anchor cables. When the steel-sheet pile touched the anchor cable during pile jacking, the compressive stress at the pile cap increased rapidly until it reached 62.8 MPa (the maximum pressure provided by the pile-pressing machine), which is twice the pressure under ordinary conditions. The maximum horizontal displacement of the retaining pile, δv, increased linearly with the excavation depth He. Existing anchor structures behind the excavation can restrain the deformation of the ground and retain the structure to a certain extent. The δv value of the pile with existing anchor structures behind is 6.5 mm or approximately 0.01% of the He value, which is 70% of that of the retaining pile without existing anchor structures. “Groove type” ground surface settlements are found on both sides of the excavation. The maximum ground settlements δh are 0.29% He and 0.05% He, respectively. The plastic zone at both sides of the excavation bottom extends to the ground surface with an angle of about 45°. When an excavation fails, the plastic zone range in the ground with existing anchor cables is significantly larger than it is in the ground without anchor cables. The key contribution of this research is to provide an effective and low-budget treatment for pipe-jacking crossing through an anchor-cable group region. The findings from this study also provide industry practitioners with a comprehensive guide regarding the specific applications and mechanical performance of the crossing excavation for obstacle treatment.
Mesozoic magmatic evolution of the Laiyuan complex: Tracing the crust-mantle and lithosphere-asthenosphere interactions in the central North China Craton
Authors: Xue Fei , Santosh M. , Tsunogae Toshiaki , Yang Fan , Tan Hongbing , Chen Guohui , Li Chao , Xu Yunchou 
Published: January 2023

The Laiyuan complex in the central North China Craton (NCC) incorporating different magmatic suites offers an excellent opportunity to investigate the lithospheric evolution and cratonic destruction. However, the petrogenesis and tectonic implications of this magmatic suite remain debated due to lack of integrated studies. Here we evaluate the magmatism and tectonic setting assembling data from multidisciplinary investigations of the Laiyuan complex. The complex is composed of volcanic suites, granitoids, ultramafic-mafic intrusions, and dykes showing common features of enrichments in LREEs and LILEs and depletions in HFSEs. Detailed petrogenetic considerations suggest that crust-mantle and lithosphere-asthenosphere interactions contributed to the formation of various magmatic suites. The involvement of thickened lower crust and enriched lithospheric mantle in the source, and diverse magmatic processes including partial melting, fractional crystallization, and magma mixing have played a significant role in the petrogenesis of the Laiyuan complex. Furthermore, the lithosphere-asthenosphere interaction induced by thinning lithosphere and upwelling asthenosphere controlled the source variations from dolerites to lamprophyres. The complex formed in an extensional tectonic setting triggered by the subduction of the Paleo-Pacific Plate. The subduction, rollback, and stagnation of the Paleo-Pacific slab contributed to the modification of the lithospheric architecture of the North China Craton. A slow and gradual thermal-mechanical erosion occurred at the central North China Craton whereas the rapid and intense lithospheric delamination occurred at the eastern North China Craton contributing to different lithospheric evolution. Both of the mechanisms combined with the subduction of Paleo-Pacific slab played a significant role in the destruction of the North China Craton and the formation of various magmatic suites. An integrated model is proposed to describe the magmatic evolution of the Laiyuan complex. During Jurassic, the subduction of the Paleo-Pacific Plate reached beneath the central North China Craton. At 145–140 Ma, the fast slab rollback occurred and lead to hot asthenosphere upwelling and extensional setting in the central North China Craton inducing the crust-mantle interaction accounting for the petrogenesis for the formation of granitoids with MMEs (137–126 Ma), volcanic rocks (131–127 Ma), and felsic dykes (131–127 Ma). Through time, the lithosphere became substantially thin with the asthenospheric input increasing to form dolerite dykes at 125–117 Ma and lamprophyre dykes at 115–111 Ma.
Numerical study on the impact of water-rock interactions on the propagation of water-flooding induced fracture
Authors: Qu Hongyan , Peng Yan , Pan Zhejun , Xu Xiangdong , Zhou Fujian 
Published: January 2023

Introcution: Water-flooding is an effective way to develop the extra-low permeability oil reservoirs and the water-flooding induced fracture (WIF) can improve waterflooding efficiency. However, geomechanical properties of rocks may alter due to the water-rock interactions, which usually increases the heterogeneity of reservoir properties and affects the WIF propagation.Methods: In this study, a method to calculate the WIF propagation length was proposed and numerical models were established considering the effect of water-rock interactions on geomechanical properties. In addition, the numerical model of stress distribution of the WIF propagation was validated by theoretical solutions based on the fracture mechanics. Moreover, the WIF propagation mechanism and the effect of water-rock interactions on the WIF propagation was analyzed.Results: Results indicate that the numerical model is valid to calculate the stress distribution induced by the WIF with an error under 5%. In addition, the WIF propagation can be affected by several factors, including the injection pressure, the damage variable and the initial fracture length. Noteworthy, the injection pressure should be strictly controlled because the WIF propagation is highly sensitive to the injection pressure. An increase of 2 MPa in the injection pressure can result in 90 m WIF propagation length, accounting for 64% of initial fracture length in the case studied in this work.Discussion: Moreover, water-rock interactions aggravate the heterogeneity of the reservoir and promote the WIF propagation due to the alteration of the geomechanical properties such as Young’s modulus. Therefore, the WIF can propagate even if the injection pressure is less than the minimum horizontal stress. Furthermore, the stress intensity factor (KIA) and WIF propagation length increase with the initial fracture length, which may lead to sudden water flux and reduce the efficiency of waterflooding.
Organizational preparedness domains and indicators of educational organizations for students with disabilities in pandemic times: A scoping review
Authors: Vlachou Anastasia , Kalaitzi Stavroula , Tsermidou Lia , Toulia Anastasia , Papazoglou Theodora , Fyssa Aristea , Papazis Filippos 
Published: January 2023

BackgroundThe impact of the COVID-19 pandemic on educational systems has caused a profound shift in the organization and delivery of education worldwide. The effects of the pandemic crisis on educational systems proved to be detrimental for students with disabilities, highlighting not only the looming social and educational inequalities but also the huge gap in organizational preparedness for education, including identifying the main areas (domains) of preparedness that guide the process of organizational preparedness and the sub-themes (indicators) per domain that help educational organizations to evaluate their level of preparedness and to identify potential gaps and set priorities for preparedness planning.MethodsScoping review with thematic analysis was performed on literature published from 2010 to 2022. Six scientific databases (PsycInfo, Web of Science, Eric, Scopus, Proquest, JSTOR) and one academic search engine (Google Scholar) were examined in order to identify publications (peer-reviewed and preprint) in English. The search strategy and robust eligibility criteria were defined by the authors, who also performed screening of the papers, eligibility decisions, and key data extractions. A thematic analysis was applied to define the organizational preparedness domains and indicators per domain, informed by a system thinking approach for educational organizations. Conflicts were collaboratively resolved after each step. All members of the research team were involved in the data synthesis.ResultsFrom 1,564 publications identified, 216 were included in the final analysis. Six domains and 14 indicators were identified.ConclusionThe organizational preparedness in educational organizations in pandemic crisis times needs to be prioritized in the educational policy agenda, drawing special attention on students with disabilities. The identified preparedness domains and indicators may guide the policy dialogue and inform accordingly a system thinking change approach in education and disability.
Sodium glucose co-transporter 2 (SGLT2) inhibition via dapagliflozin improves diabetic kidney disease (DKD) over time associatied with increasing effect on the gut microbiota in db/db mice
Authors: Wu Jiajia , Chen Yan , Yang Huinan , Gu Leyi , Ni Zhaohui , Mou Shan , Shen Jianxiao , Che Xiajing 
Published: January 2023

BackgroundThe intestinal microbiota disorder gradually aggravates during the progression of diabetes. Dapagliflozin (DAPA) can improve diabetes and diabetic kidney disease(DKD). However, whether the gut microbiota plays a role in the protection of DAPA for DKD remains unclear.MethodsTo investigate the effects of DAPA on DKD and gut microbiota composition during disease progression, in our study, we performed 16S rRNA gene sequencing on fecal samples from db/m mice (control group), db/db mice (DKD model group), and those treated with DAPA (treat group) at three timepoints of 14weeks\18weeks\22weeks.ResultsWe found that DAPA remarkably prevented weight loss and lowered fasting blood glucose in db/db mice during disease progression, eventually delaying the progression of DKD. Intriguingly, the study strongly suggested that there is gradually aggravated dysbacteriosis and increased bile acid during the development of DKD. More importantly, comparisons of relative abundance at the phylum level and partial least squares-discriminant analysis (PLS-DA) plots roughly reflected that the effect of DAPA on modulating the flora of db/db mice increased with time. Specifically, the relative abundance of the dominant Firmicutes and Bacteroidetes was not meaningfully changed among groups at 14 weeks as previous studies described. Interestingly, they were gradually altered in the treat group compared to the model group with a more protracted intervention of 18 weeks and 22 weeks. Furthermore, the decrease of Lactobacillus and the increase of norank_f:Muribaculaceae could account for the differences at the phylum level observed between the treat group and the model group at 18 weeks and 22 weeks.ConclusionWe firstly found that the protective effect of DAPA on DKD may be related to the dynamic improvement of the gut microbiota over time, possibly associated with the impact of DAPA on the bile acid pool and its antioxidation effect.