bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN ANTARA PEMBERIAN REMUNERASI TERHADAP KINERJA KARYAWAN DI RUMAH SAKIT ISLAM SITI KHADIJAH PALEMBANG
Authors: Juairiah Juairiah , Malwa Rosyidah Umpu 
Published: February 2023

This study determines whether there is a relationship between the remuneration to the employee performance at the Islamic Hospital Siti Khadijah Palembang. The hypothesis of this study is no significant relationship between the remuneration to the employee performance in The Islamic Hospital Siti Khadijah Palembang. There are two variables in the study of variable remuneration X and Y performance. The method used is quantitative correlation. The sampling technique in studies using stratified random sampling, and found the number of sampling as many as 50 people. Instrument collecting data in this study using a scale of remuneration and performance scale. Hypothesis testing using a hypothesis test analysis of SPSS version 22.0 for Windows. The results of data analysis based on the analysis of the Kearl Person Product Moment showed that there is a significant correlation (r s> r table) = 0.666> 0.279 with significance level of 0.05. This indicates the higher administration remunersi the employee's performance will increase.
Quando devoção e carnaval se encontram
Authors: Menezes Renata , Bártolo Lucas 
Published: February 2023

A partir de experiências etnográficas com enredos de escolas de samba do Rio de Janeiro que contêm referências religiosas, este artigo tem por objetivo apontar possibilidades de articulação entre festa, arte, cultura e religião. Toma-se por base o acompanhamento dos desfiles da Renascer de Jacarepaguá, em 2016, em homenagem aos Ibeijis, santos e orixás gêmeos, e da Estação Primeira de Mangueira, em 2017, com um enredo que tratava das relações entre santos e devotos. As etnografias foram realizadas de forma coletiva por membros do Grupo de Pesquisa em Antropologia da Devoção do Museu Nacional/UFRJ, que partiram de um repertório acumulado de discussões na área da “antropologia da devoção” e no estudo das religiões ou das festas religiosas stricto sensu. Porém, o processo de aproximação ao universo das escolas de samba produziu uma abertura de horizontes, provocada pela experiência de abordar a religião como temática carnavalesca. São as descobertas e os impasses dessa mudança de contexto em um percurso de pesquisas que procuraremos explorar aqui.
Apresentação em vídeo: https://youtu.be/uDLKJcDKpgM
Recruitment of plasma cells to the bone marrow in primary and secondary immune reactions
Authors: Ferreira-Gomes Marta , Durek Pawel , Chen Yidan , Rincon-Arevalo Hector , Heinrich Frederik , Szelinski Franziska , Guerra Gabriela , Stefanski Ana-Luisa , Niedobitek Antonia , Wiedemann Annika , Bondareva Marina , Ritter Jacob , Lehmann Katrin , Hardt Sebastian , Hipfl Christian , Hein Sascha , Hildt Eberhard , Matz Mareen , Mei Henrik , Cheng Qingyu , Dang Van Duc , Witkowski Mario , Lino Andreia , Kruglov Andrey , Melchers Fritz , Perka Carsten , Schrezenmeier Eva , Radbruch Andreas , Dörner Thomas , Mashreghi Mir-Farzin 
Published: February 2023

Abstract

Bone marrow plasma cells (BMPC) emerge as a consequence of immune reactions and are considered the source of antibodies that protect against recurrent infectious diseases throughout life. Despite their importance, it remains unclear if these cells reflect different activation environments or the differentiation/maturation stages of their precursors. Here we track the recruitment of plasma cells, generated in primary and secondary immune reactions to SARS-CoV-2 spike protein vaccines, to the human bone marrow. Trajectories based on single cell transcriptomes and antigen-receptor clonotypes of antibody-secreting cells exiting the immune reaction and of those residing in the bone marrow, allow to follow the evolution of the immune response to these vaccines, leading to sequential colonization of these cells to different compartments (clans) of BMPC, and their establishment as long-lived (memory) plasma cells. In primary immune reactions, both CD19low (clans 1 and 4) and CD19high (clan 0) BMPC are generated. In secondary immune reactions, mostly CD19high BMPC of the largest compartment (clan 0) are generated, resulting from the reactivation of memory B lymphocytes. The latter is also observed in vaccinated convalescent individuals and upon recall vaccination against diphtheria/tetanus/pertussis (DTP). Thus, humoral immunological memory, i.e. serum antibodies secreted by long-lived memory BMPC, is generated already in the primary immune response, more so in the secondary, and it represents the evolution of the immune response.
A Reliable Diabetic Retinopathy Grading via Transfer Learning with Quadratic Weighted Kappa Metric
Authors: Chilukoti Sai Venkatesh , Shan Liqun , Maida Anthony S , Hei Xiali 
Published: February 2023

Abstract
Diabetic Retinopathy (DR), the most prevalent eye condition in diabetic patients, can be brought on by diabetes. It may result in reduced eyesight or possibly complete blindness. Early detection can help prevent eye damage, but it can be challenging because symptoms might not show up right away. To grade diabetic retinopathy and identify all stages of DR, many predictive models based on machine learning and deep learning have been proposed. However, the majority of the diabetic retinopathy grading models now in use cannot identify all stages. For DR grading, the most used metrics, including as accuracy, f1-score, precision, recall, and AUC-ROC score, are unreliable. Since they do not consider the level of disagreement between target and predicted labels and the ordinality of target labels, which helps classify all DR stages. To address these issues, we developed the customized EfficientNet b3. The Quadratic Weighted Kappa (QWK) was chosen as the primary evaluation metric since the distinct stages of diabetic retinopathy are ordinal. The degree of discrepancy between the actual and expected labels is also taken into consideration. We were able to achieve a higher QWK score of 0.87 by recognizing all the DR stages after aggregating the predictions from the efficientnet-b3 model, which was trained for 30 and 60 epochs, respectively. This result is state-of-the-art. DR grading must identify each stage in order to provide patients with the greatest care available. Our Confusion matrix of ensembled efficientnetb3 shows, which is state-of-the-art, that all DR stages are identified with higher probabilities.
Is it safe to commercialize ornamental plants irrigated with antimicrobial-contaminated water?
Authors: Rocha Camila Silva , Kochi Leticia Yoshie , Brito Julio Cesar Moreira , Kitamura Rafael Shinji Akiyama , Carneiro Daniella Moreira , Reis Michele Valquíria dos , Gomes Marcelo Pedrosa 
Published: February 2023

Abstract
Enrofloxacin (Enro) has been widely encountered in natural water sources, and that water is often used for irrigation in crop production systems. Due to its phytotoxicity and accumulation in plant tissues, the presence of Enro in water used for crop irrigation may represent economical and toxicological concerns. Here, we irrigated two ornamental plant species (Zantedeschia rehmannii and Spathiphyllum wallisii) with water artificially contaminated with the antimicrobial enrofloxacin (Enro; 0, 5, 10, 100 and 1000 µg L− 1) to evaluate its effects on ornamental plant production, as well as its accumulation and distribution among different plant organs (roots, leaves, bulbs, and flower stems), and examined the economic and environmental safety of commercializing plants produced under conditions of pharmaceutical contamination. The presence of Enro in irrigation water was not found to disrupt plant growth (biomass) or flower production. Both species accumulated Enro, with its internal concentrations distributed as following: roots > leaves > bulbs > flower stems. In addition to plant tolerance, the content of Enro in plant organs indicated that both Z. rehmannii and S. wallisii could be safety produced under Enro-contaminated conditions and would not significantly contribute to contaminant transfer. The high capacity of those plants to accumulate Enro in their tissues, associated with their tolerance to it, indicates them for use in Enro-phytoremediation programs.
Development of a Neonatal Incubator for Community Health Care Centres in Ghana
Authors: Shankar Srinivasan Balapangu , Amoako Emmanuel , Gavi Vanessa Naki , Dzidah Ebenezer , Razak Nana Ayisha Abdul , kumordzi Prince , Narh Sosi Alaric , Kuuziile Mark Konyele 
Published: February 2023

Abstract
A newborn baby less than 28 days is considered a neonate, according to the World Health Organization. A child has the greatest chance of dying within the first 28 days of life. This is due to the fact that a newborn's body is still developing. Neonatal have respiratory problems and can't regulate their body temperatures. In Ghana, neonatal deaths account for around half of all pediatric mortality. Most of these fatalities occur at nearby medical facilities. This is because incubators are now too expensive and challenging to access in such places. The most well-known modern methods—the heated cot and kangaroo mother care—have drawbacks but are nonetheless widely used today. With this research, a low-cost neonatal incubator will be created for Ghanaian community healthcare facilities. The incubator generates heat from LED stripes, which may be operated by a minimum voltage of 19V, rather than the heated filament found in conventional incubators. In order to keep the infant alive, this created the correct humidity and temperature conditions. For use during power outages, load shedding, or interruptions, a power bank was constructed using a simple laptop battery. Temperature and humidity levels are maintained via the incubator's central cooling system, which consists of a fan and an atomizer. Last but not least, the housing of the incubator was created utilizing widely accessible and inexpensive bamboo and acrylic. Adopting this plan will therefore aid in lowering Ghana's high infant mortality rate in rural communities.
Comparison of the macular vascular densities between molecularly confirmed MODY patients with GCK variants and age-matched healthy controls
Authors: Çavdarli Cemal , Büyükyılmaz Gönül , Çavdarlı Büşranur , Çomçalı Sebile , Yılmaz Pınar Topçu , Alp Mehmet Numan 
Published: February 2023

Abstract
Background: Several structural, vascular density and perfusion studies were conducted in type 1 and 2 diabetes, even in the absence of retinopathy. The current study is the first to compare macular vessel densities (VD) by optical coherence tomography angiography (OCTA) between maturity onset diabetes of the young (MODY) patients and healthy controls.
Methods: The macular VD of superficial, deep retina, and choriocapillaris, and central macular thickness (CMT), foveal avascular zone area (FAZ), FAZ perimetry, VD of total retina at 300µm around the FAZ (FD), acirculatory index (AI) measurements were captured by the OCTA, which operates with built into software (RTVue-XR100-2 Avanti, Angiovue), and were compared between molecularly confirmed (GCK mutations) MODY patients and controls.
Results: Twenty-five MODY patients and 30 controls were included. Mean plasma HbA1c level of the MODY group was 6.39±0.38 (min:5,4 max:6,9, %). Average age was 13.8±2.1 in the MODY group, and was 12.6±2.5 years among controls. There was no significant difference in terms of age, superficial and deep retinal VD, FAZ, FAZ perimetry, CMT, FD, and AI between groups. Significant increase of VD only at the parafoveal and perifoveal regions of choriocapillaris in the MODY group was observed (P=0.034 and P=0.009).
Conclusion: No significant difference of macular VD was observed between non-retinopathic MODY patients and controls, except VD of choriocapillaris at the parafovea and perifovea. Previous thickness and VD results were distributed in a wider range suggesting not yet defined factors may be affecting the choroidal vasculature independent of glycemia or as a contributing factor.
Neoadjuvant chemotherapy for triple negative and Her2+ve breast cancer: striving for the standard of care
Authors: Roberts Amanda , Hallet Julie , Nguyen Lena , Coburn Natalie , Wright Frances C. , Gandhi Sonal , Jerzak Katarzyna , Eisen Andrea , Hong Nicole J Look 
Published: February 2023

Abstract

Purpose
Neoadjuvant chemotherapy (NAC) for triple negative (TN) and Her2 positive (HER2) breast cancers is supported by international guidelines as it can decrease extent of surgery, provide prognostic information and allow response-driven adjuvant therapies. Our goal was to describe practice patterns for patients with TN and HER2 breast cancer and identify factors associated with the receipt of NAC versus surgery as initial treatment.
Methods
A retrospective population-based cohort study of adult women diagnosed with stage I-III TN or HER2 breast cancer (2012-2019) in Ontario was completed using linked administrative datasets. The primary outcome was NAC as first treatment. The association between NAC and patient, tumour, and practice-related factors were examined using multivariable logistic regression models.
Results
Of 12,881 patients included, 22.9% (n = 2952) underwent NAC as first treatment. Patients who underwent NAC were more likely to be younger, have larger tumors, node positive disease and stage 3 disease. Of patients who underwent surgery first, 8.4% were seen by a medical oncologist prior to surgery. On multivariable analysis, increasing tumor size (T2 vs T1/T0: 2.63 (2.13 - 3.25)) and node positive (N1 vs N0: 3.60 (2.88 - 4.50)) disease were both associated increased odds of receiving NAC.
Conclusion
A considerable proportion of patients with TN and HER2 breast cancer do not receive NAC as first treatment. Of those, most were not assessed by both a surgeon and medical oncologist prior to initiating therapy. This points towards potential gaps in multidisciplinary assessment and disparities in receipt of guideline-concordant care.
Automatic generation of water distribution networks using central street lines.
Authors: Frota Artemisa Fontinele , Costa Luis Henrique Magalhães , Costa José Nilton de Abreu , de Castro Marco Aurélio Holanda 
Published: February 2023

Abstract
This paper puts forth a dedicated algorithm for automatic generation of water distribution networks based solely on street layouts designed in a CAD environment. In the model, any detected street boundaries are converted into lines that are subjected to a mathematical treatment via parametric representation. These central street lines are extended to generate intersections, which are then used to determine the location of the network’s nodes and later the pipes connecting the nodes. Two different layouts were used to ascertain the efficacy of the model, one hypothetical and one real. The algorithm was considered to yield satisfactory results as it automatically generated the entire grid plan in an EPANET input file for both layouts.
CT features of eosinophilic gastroenteritis
Authors: Liu Yan , Wang Shanshan , Niu Junqiao , Wang Jia , Li Xiaojuan , Li Jingjing , Wang Yan 
Published: February 2023

Abstract
Background
This study aimed to investigate the features and diagnostic value of computed tomography (CT) in eosinophilic gastroenteritis (EG).
Methods
Twenty patients pathologically diagnosed with EG by gastroscopy and enteroscopy were retrospectively analyzed to determine the imaging features of EG.
Results
Among the patients diagnosed with EG in this study, fifteen demonstrated a predominantly mucosal type, nine of whom had EG involving the gastric wall. CT findings showed gastric wall thickening, submucosal edema, and intraluminal granuloma mimicking a polyp. Six of the patients had EG involving the small bowel, presenting as bowel wall thickening and “araneid-limb-like” sign. One patient had muscular type EG found in the ileocecus, with CT revealing luminal narrowing with obstruction, mimicking a soft tissue mass, and a small amount of fluid in the abdominal cavity. One patient had serosal type EG observed in the colon, with CT revealing pronounced wall thickening of the hole in the colon with evident contrast enhancement of the outer layers, “comb sign,” increased enhancement of the mesentery and fat tissue of the small bowel, and little amount of fluid in the abdominal cavity. In three patients with mixed type EG, lesions were patchy and multiple and localized or diffuse, and irregular wall thickening of multiple inhomogeneous reinforcement, with skipped areas, and mural stratification and multi-circumferential enhancement were observed.
Conclusions
Considering that each type of EG has characteristic CT appearance, combined with typical clinical features and peripheral blood eosinophilia, establishing an appropriate diagnosis of EG is significant.
Production, large-scale extraction and purification of phycocyanin by potential of different strains of cyanobacteria isolated from various environments
Authors: Hajiyeva SONA , CANKILIC Meral Yılmaz , SARIÖZLÜ Nalan Yılmaz 
Published: February 2023

Abstract
Blue-green cyanobacteria, which have attracted great interest in recent years due to their potential applications in biotechnology, have an essential ability to synthesize natural pigments of different colors. The chosen study is aimed at investigating the strain with the highest phycocyanin yield among the five cyanobacterial strains isolated from the wastewaters of Porsuk river, thermal springs, and boron-bearing waters of Eskişehir county of Turkey, and optimized studies, purification, and characterization for increasing the phycocyanin yield. At the initial stage, the phycocyanin yield was analyzed by applying four different extraction methods - freeze-thawing, sonication, homogenization, and treatment with lysozyme - to the selected strains. The most appropriate strain sonication method was selected and thermophilic Geitlerema sp was obtained with 116 ± 0.18 mg g− 1 phycocyanin. The crude extract obtained following the optimized studies was first purified by solid ammonium sulfate precipitation/dialysis at 50% and 75% saturation, and then by ion-exchange chromatography using two anionic resins (DEAE -cellulose, and Q -sepharose). The purity rate determined in the spectrum was recorded as 4.12 with 48.9% recovery (A620/A280). The molecular weights of the α and β subunits were found to be 17 kDa to 19 kDa, respectively, by characterization using the SDS-PAGE method. In addition, the effect of purified thermal phycocyanin at different temperatures was examined, the CR value of its pigment was determined to be stable by resisting at high temperatures up to 60Cº. Generally, in the study, a thermostable C-phycocyanin was purified from Geitlerema sp, which may be differentiated commercially from other mesophilic species.
Perceived health-related quality of life among patients living with cancer at Kamuzu Central Hospital in Malawi
Authors: Banda Jonathan Chiwanda , Bula Agatha , Tsidya Mercy , Udedi Michael , Muula Adamson Sinjani 
Published: February 2023

Abstract
Patients living with cancer and their families experience several challenges that affect their health-related quality of life (HRQOL). Perceived factors affecting quality of life (QOL) among people living with cancer have rarely been studied. We aimed at exploring the factors perceived to be associated with health-related quality of life among people living with cancer attending to a National Cancer Centre at Kamuzu Central Hospital in Malawi. Between May and June 2022, we conducted a qualitative study to assess perceptions and the in-depth lived experiences for people living with cancer, caregivers and healthcare workers at the cancer center on health-related quality of life. We purposively selected and interviewed thirteen participants. Interviews were transcribed, coded using NVivo 12 and analyzed using thematic analysis. Two broad categories of emerging themes of quality of life were identified. These included: (a) individual level factors such as experiences with diagnosis and treatment, changes on physical, psychological and social health, support received, benefits and challenges, (b) facility level factors such as availability of resources, relationship with providers, satisfaction with cancer care, facility organization, facilitators and barriers to improved quality of life. This study has highlighted the importance of physical, psychological, and social factors as key determinants perceived to be affecting health-related quality of life among patients living with cancer and their caregivers at the National Cancer Centre, Kamuzu Central Hospital in Malawi. The QOL challenges experienced by patients and their caregivers, implied that cancer care interventions should consider a holistic approach to cover for all dimensions of life in order to improve health-related quality of life among patients living with cancer.
Evidence of Lightning and Gravity wave signatures produced by the Hunga-Tonga Volcanic eruption on Global geomagnetic data
Authors: Chandrasekhar N. Phani , Archana R. K. , Arora Kusumita 
Published: February 2023

Abstract

Global disruptions were noticed after the Hunga-Tonga volcanic eruption on January 15th 2022, which released an enormous amount of mass and energy into the atmosphere. Since there are many facets associated with this event, the primary focus of this investigation is on the following: (i) changes in the Schumann resonance (SR) modes as a result of the discharge of lightning strikes and (ii) global geomagnetic disturbances due to acoustic-gravity waves (AGWs). The results of our analysis show the noticeable changes in SR frequency modes (i.e. 7 to 21 Hz), between 04:15 and 05:45 UT hours in the high-frequency 64Hz scalar magnetic field (F) data derived from Induction coil magnetometer at Patiyasar (Himalayan region) and the propagation velocity of geomagnetic disturbances is found to be 269.68 ± 5 m/s, corresponding to the acoustic-gravity wave velocity, derived from the scalar magnetic field from the fluxgate magnetometers from 20 geomagnetic observatories (18 INTERMAGNET and 02 non- INTERMAGNET) world-wide located between 800 and 16000 km away from Tonga volcano. By comparing the lag time between the observed Schumann resonance and the negative bay, this study confirmed the velocity of the acoustic-gravity wave (296.76 ± 5 m/s, which closely corresponds to the estimated AGWs velocity: 269.68 ±5 m/s) with a delay of 11.48 ± 0.25 UT hour from a single geomagnetic observatory, Patiyasar (15000 km from Tonga). The variance in velocities could be attributed to the role of atmospheric-ionospheric winds and different ionosphere conditions.
WBE joins AI: improving WBE protocols to support the construction of predictive ML models
Authors: Bonifácio Carmen L.C , Krempser Eduardo , Pedroso Marcel , Porto Fábio 
Published: February 2023

Abstract
Wastewater Based Epidemiology (WBE) supports sanitary surveillance enablingan early identification of viral spread. The procedure involves the genome copy(GC) of SARS-CoV-2 capture from sewage samples infected by symptomatic andasymptomatic people. During the pandemic of COVID-19 in Brazil(2020/2021)the WBE studies followed different guidelines still incipient, revealinglow concern for a common agreed-upon procedure. As a result, when compilingthe available WBE data for the training of Artificial Intelligence (AI) models forCOVID-19 number of cases prediction, we found few quantity, obtained throughdifferent adopted procedures and difficult to co-related to extra information. Thelack of a common WBE procedure makes it hard to build useful predictiveMachine Learning (ML) models. In this context, guidelines that link ML andWBE are explored here. We aim at raising an alert highlighting the relevance onthe design of useful strategies to join WBE and IA. The proposal aims atstandardization and consistency without any detriment to the initial objective ofsurveillance. The approach includes processes related to: the definition of samplecollection approach, sampling frequency, related information, physical andtemporal sample characteristics, laboratory methods for genes amplification anddetection and results dissemination.