bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biological Activity of Ganoderma Species (Agaricomycetes) from Sonoran Desert, Mexico
Authors: Bacallao-Escudero Alexander , Guerrero-Germán Patricia , Torres-Moreno Heriberto , Vidal-Gutiérrez Max  , López-Romero Julio César , Tejeda-Mansir Armando , Esqueda Martín , Robles-Zepeda Ramón Enrique 
Published: August 2023

<i>Ganoderma</i> species have been used in folk medicine against different illnesses and are characterized by producing a diversity of bioactive metabolites (triterpenoids, polysaccharides, flavonoids, and phenols) with numerous medicinal effects (anti-proliferative, antioxidant, anti-inflammatory, and antibacterial). This work aims to evaluate ethanolic extracts of fruiting bodies of <i>Ganoderma oerstedii, G. weberianum</i>, and <i>G. subincrustatum</i> strains from the Sonoran Desert in the anti-proliferative activity by the MTT assay on cancer cell lines; anti-inflammatory effect by quantifying nitric oxide (NO) production; antioxidant activity by DPPH, ABTS, and FRAP assays; total phenolic and flavonoid content by Folin-Ciocalteu and AlCl<sub>3</sub> method, respectively; antibacterial activity by the broth microdilution method against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i>. Extracts showed anti-proliferative activity with IC<sub>50</sub> &#60; 100 &#181;g/mL on the cancer cell lines MDA-MB-231, A549, and HeLa, except <i>G. subincrustatum</i> extract with an IC<sub>50</sub> &#62; 100 &#181;g/mL; anti-proliferative activity was not selective, being affected non-cancerous cell line ARPE-19. Extracts showed significant inhibition of NO release in cells stimulated by LPS, up to 60&#37; with <i>G. subincrustatum</i> and <i>G. oerstedii</i>, and 47&#37; with <i>G. weberianum</i>. All tested assays showed moderate antioxidant potential; the most active was <i>G. lucium</i> (control strain) with IC<sub>50</sub> of 69 and 30 &#181;g/mL by DPPH and ABTS respectively; and 271 &#181;g Trolox equivalents/g by FRAP. Total phenols and flavonoids ranged from 38 to 56 mg GAE/g and 0.53 to 0.93 mg QE/g, respectively. A significant correlation was found between the antioxidant activities revealed by DPPH, ABTS, and FRAP with total phenol and flavonoid contents. Antibacterial activity was weak against <i>S. aureus</i> (MIC<sub>50</sub> &#62; 10 mg/mL). These results demonstrate that tested <i>Ganoderma</i> mushrooms have medicinal potential such as anti-inflammatory and anti-proliferative.
Crushed amygdaloidal basalt rock and its effects on tomato production
Authors: Dalmora Adilson Celimar , Müller Kautzmann Rubens , Staubc Jair , Homrich Schneider Ivo André 
Published: August 2023

Abstract
Sustainable agriculture plays an important role in agricultural productivity, in which it seeks to reduce dependence on conventional synthetic fertilizers (imported from Europe) and promote the use of alternative, low-cost and environmentally friendly sources. An experiment was carried out in the municipality of Santa Maria, Rio Grande do Sul, Brazil, with the objective of evaluating the efficiency and agronomic viability of using a mineral product (amygdaloid basalt powder) as an agricultural input on tomato productivity Solanum lycopersicum. The experimental design used was randomized blocks with six treatments and four replications, at doses 0 (treatment 1 - control), 1.0 ton ha-1 of rock dust (treatment 2), 2.5-ton ha-1 of rock dust (treatment 3), 3.5-ton ha-1 of rock dust (treatment 4), 4.5-ton ha-1 of rock dust (treatment 5), and recommended fertilization for tomato 5-20-20 NPK (treatment 6 - standard). The treatments were applied in December 2018 and the transplant took place in February 2019. According to the conditions under which the experiment was submitted and analyzing the results obtained, it can be inferred that the application of 1-ton ha-1 of amygdaloidal basalt in the soil increased parameters such as root length, stem diameter, green and dry mass of shoots and roots, number of flowers/plants, number of fruits/plant and productivity in tomato Solanum lycopersicum. It is a viable, sustainable, and low-cost strategy that contributes to the achievement of the Sustainable Development Goal (SDG 2) and can be replicated in Brazil and worldwide.
La traducción inglés > español de verbos de manera de movimiento en el subtitulado de documentales deportivos de Netflix enfocada en el aprendizaje de lenguas
Authors: López Martínez Leticia , Guerrero García Sandra 
Published: August 2023

El presente trabajo se centra en explorar cuál es el grado de especificidad con el que se traducen los verbos de manera de movimiento del inglés al español en el ámbito de los deportes. Para ello se han utilizado dos documentales deportivos de la plataforma Netflix (Home Game y The Playbook) y se han analizado los subtítulos que ofrece la extensión Language Reactor en ambas lenguas. El objetivo es comprobar si es posible utilizar estas herramientas como recurso para el aprendizaje de patrones de lexicalización de movimiento en el proceso de adquisición de segundas lenguas. Se analiza del nivel de inclusión de información sobre la manera empleado por el traductor y los resultados apuntan a que la combinación de Netflix y Language Reactor no resulta un recurso conveniente para el aprendizaje de los patrones de lexicalización del movimiento. Sin embargo, sí supone una fuente de contenido didáctico para crear actividades de foco en la forma, método apropiado para este tipo de contenido gramatical más pormenorizado.
La réalisation des métaphores conceptuelles de la vaccination contre le COVID-19 en français et en tchèque
Authors: Mazurkiewicz Paulina , Lazar Jan 
Published: August 2023

Cet article vise à analyser l’expression de la métaphore conceptuelle du vaccin contre le Covid-19 dans le discours médical de vulgarisation en français et en tchèque. Nous avons sélectionné, comme corpus de recherche, des sites Internet de vulgarisation médicale, en prenant en compte le sujet de la vaccination contre le Covid-19 (doctissimo.fr pour la langue française et www.idnes.cz pour la langue tchèque). Les recherches menées montrent un réseau de métaphores pour expliquer un phénomène complexe de lutte efficace contre le virus qui cause cette maladie. Les experts se réfèrent à la métaphore structurelle montrant le transfert des structures conceptuelles du domaine source OPÉRATION MILITAIRE vers le domaine cible VACCINATION. À son tour, le vaccin conceptualisé comme SOLDAT est un exemple d’anthropomorphisation dans une métaphore ontologique. L’examen du corpus comparable a montré une quantité importante d’équivalences lexicales et syntaxiques totales résultant d’une même perception de la réalité pandémique par les Tchèques et les Français. D’autre part, cela peut être dû à la référence à l’anglais, dans lequel la recherche scientifique mondiale s’exprime le plus souvent.
Carbapenem-Resistant Enterobacterales Infections and Their Association with Rectal Colonization
Authors: AYDEMİR Özlem , KÖROĞLU Mehmet , ORMANOĞLU Gökçen , AYHANCI Tuğba , AYDEMİR Yusuf , GÜÇLÜ Ertuğrul 
Published: August 2023

Objectives: Carbapenem-resistant Enterobacterales (CRE) infections have limited treatment options, and these infections are associated with high mortality rates. Asymptomatic carriers colonized with CRE contribute to the spread of CRE in hospitals. It was aimed to determine the frequency of CRE isolates detected in our center, carbapenemase ratios in these strains, carbapenemase genes, antibiotic resistance profiles, rectal CRE colonization rates and to evaluate various clinical features of CRE infections.
Methods: Enterobacterales species isolated from various specimens and Enterobacterales species isolated from rectal swab specimens sent for colonization screening were examined. Patients with CRE colonization in rectal swab samples were examined for the development of CRE infection at a later time. CRE isolates were examined for carbapenemase production and the presence of carbapenemase gene.
Results: 12,721 Enterobacterales (10,161 E. coli and 2395 K. pneumoniae, 165 Citrobacter) isolates were examined. Carbapenem resistance was detected in 10.3% of these strains. CRE was detected in 4.7% of 15695 rectal swab samples evaluated for colonization. In 23.4% of the patients with CRE colonization, CRE growth was detected in other samples besides the rectal swab in the later period. It was observed that CRE infections developed on average 21 days after colonization.
Conclusion: CRE infections have started to emerge as a factor not only in hospitalized patients but also in community-acquired infections. Our study also showed that CRE colonization could be a significant risk factor for the development of infection. Therefore, early screening detection to detect colonization can help prevent or limit CRE infections with appropriate isolation methods.
The Turkish Validity and Reliability of the Coronavirus-Related Health Literacy Scale on Health Science Students
Authors: PEKSOY KAYA Sibel , DEMİR Pervin , KAPLAN Sena , ŞAHİN Sevil 
Published: August 2023

Objective: Health literacy is one’s ability to access, comprehend, appraise, and apply health-related information. Health literacy has become an important topic since the COVID-19 pandemic. This methodological study aimed to adapt the Coronavirus-Related Health Literacy Scale (HLS-COVID-Q22) to Turkish.
Methods: The sample consisted of 539 students of the faculty of health sciences of a university in Turkey. The study was conducted between December 2020 and May 2021. The content validity ratio was calculated for content validity. The construct and concurrent validity, internal consistency reliability, test-retest reliability, and ceiling and floor effects were also determined. A confirmatory factor analysis was performed for construct validity.
Results: The fit indices indicated an adequate fit (2/df: 4.970.70) and Cronbach’s alpha values (>0.90) were above acceptable limits. Most students had “adequate health literacy” (71.8%). A quarter of the students had “problematic health literacy” (24.5%). The remaining students had “inadequate health literacy” (3.7%). Students with lower levels of health literacy were more likely to have confusion about coronavirus-related information (p
Pelatihan pembuatan storyboard dan games interaktif untuk guru dan mahasiswa magister pendidikan matematika
Authors: Sari Nenden Mutiara , Yaniawati Poppy , Firmansyah Eka , Mubarika Melinda Putri , Assegaff Nurani , Purwanti Nurul Septiyani Ayu 
Published: August 2023

[Bahasa]: Kemampuan guru dan mahasiswa magister pendidikan matematika dalam membuat dan memilih media pembelajaran serta mengemas proses pembelajaran berperan sangat penting dalam dalam menentukan keberhasilan dari hasil belajar. Namun, saat ini penggunaan media pembelajaran interaktif masih kurang, karena kurangnya penguasaan teknologi oleh para guru dan mahasiswa magister pendidikan matematika. Untuk mengatasi masalah tersebut, solusi yang diajukan dalam kegiatan pengabdian kepada masyarakat (PKM) ini adalah menyelenggarakan workshop tentang pembuatan storyboard dan games interaktif. Pendekatan PKM yang digunakan dalam pelatihan ini adalah Participatory Ation Reasearch (PAR). Peserta program pengabdian ini adalah guru dan mahasiswa magister pendidikan matematika. Data evaluasi hasil kegiatan PKM menunjukkan tingkat kepuasan peserta pelatihan pada kategori sangat memuaskan. Berdasarkan hasil tes yang diberikan, pelatihan dan pendampingan pembuatan storyboard dan games interaktif meningkatkan kemampuan guru dan mahasiswa magister pendidikan matematika dalam membuat media pembelajaran. Sebanyak 85% peserta pelatihan berhasil membuat storyboard dan games interaktif.
Kata Kunci: games interaktif, media pembelajaran, storyboard
[English]: The ability of master students in mathematics education to make learning media, choose learning media, and package the learning process plays a vital role in determining the success of learning outcomes. However, the use of interactive learning media is still lacking due to a lack of mastery of technology by teachers and students of master of mathematics education programs. To overcome this problem, the solution proposed in this PKM activity is to organize a workshop on making storyboards and interactive games. The PKM approach used in this training is Participatory Action Research (PAR). The participants of this program were the teachers and students of the mathematics education master's degree. Evaluation of the data shows that the level of participants was very satisfactory. The results of this program show that the training and assistance in making storyboards and interactive games increase the ability of teachers and students of mathematics education masters to make learning media. As many as 85% of the training participants succeeded in making interactive storyboards and games.
Keywords: interactive games, learning media, storyboard
AVALIAÇÃO DA ATIVIDADE CITOTÓXICA E GENOTÓXICA DE EXTRATOS DE ARRABIDAEA CHICA SOBRE O SISTEMA TESTE DE ALLIUM CEPA
Authors: Lima Silvânia Narielly Araújo , Marques de Lima Amanda , Pereira de Araújo Amanda Geovana , Vieira de Lima Santos Igor Luiz 
Published: August 2023

A Arrabidaea chica é uma planta medicinal utilizada no tratamento de diversas enfermidades, porém ainda são necessários mais estudos sobre a segurança da sua utilização, confirmando se a mesma é ou não citotóxica e/ou genotóxica. O teste Allium cepa é um bioindicador ideal para o primeiro screening da citogenotoxicidade de infusões de plantas medicinais. Por isso, esse trabalho visou avaliar a citogenotoxicidade de extratos da Arrabidaea chica sobre o sistema teste Allium cepa, cujos extratos foram preparados por infusão, decocção e maceração. Inicialmente, foi realizada a triagem fitoquímica e análise do pH dos extratos. Com o teste Allium cepa, foram avaliadas microscópica e estatisticamente aberrações cromossômicas e atividade antiproliferativa, utilizando como controle negativo a água destilada e como controle positivo o metamizol. Observou-se a presença de taninos, alcaloides e flavonoides nos 3 extratos, cujo pH variou entre 6 e 4. Não foram observadas aberrações cromossômicas nos extratos, indicando que esta não é genotóxica. Os extratos resultaram em uma diminuição no índice mitótico, em relação ao controle negativo, indicando que esta planta apresenta efeito citotóxico. Os resultados obtidos foram satisfatórios, contudo, ainda são necessários mais estudos sobre esta planta, como utilizando testes com Artemia Salina.
GENDER SEGREGATION OF HEALTH MANAGERS IN DISTRICT HEALTH OFFICERS IN INDONESIA
Authors: Marwah Shofi Kambarwati Nur , Putri Nuzulul Kusuma 
Published: August 2023

Introduction: Women dominate Indonesia's health system but there is no clear evidence how this is represented equally in the decision-making process. Globally, the healthcare system is challenged by gender segregation of health managerial position. Aims: This study is to explain the findings regarding patterns of male or female dominance in the particular division of the district health office. Methods: This study was an original research discussing gender segregation of male and female dominance as health managers in district health office. We listed the characteristics of health managers in two provinces with different kinship system. These characteristics were then compared with several gender segregation patterns i.e. work area; position requirement; dominant task coordination; workplace; emergency possibility; budget; percentage of the female manager based on matriarchy and patriarchy background. Result: Female managers of a matriarchal background dominate in General Secretariat (63.4%). Public Health and Community Empowerment (62.5%) and Healthcare Services (80%). A significant portion of men of a patriarchy background shows that men are dominating in two divisions, Disease Prevention and Control (57.8%) and Health Services (55.3%). The study proved the existence of the dominance of one gender in a specific job. This indicated the existence of gender segregation in the healthcare system. Conclusion: Female managers tend to be placed in domestic organization affairs while the male managers are generally responsible for interorganizational affairs, including jobs with high emergency responses.
DETERMINANTS OF STIGMA ON PEOPLE LIVING WITH HIV AND AIDS IN INDONESIA (EVIDENCE FROM 2017 IDHS DATA)
Authors: Adiansyah Mohammad Taufiq , Ramani Andrei , Baroya Ni'mal 
Published: August 2023

Introduction: People living with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) face bio-psycho-socio-spiritual problems. The stigma against PLWHA exists in more than 65 countries. Indonesia occupied the highest position in the Pacific with a case rate of 62.8%. Stigma has contributed to the failure of HIV and AIDS epidemic-control programs. Aims: To determine the stigma against PLWHA in Indonesia. Method: This study used the 2017 IDHS dataset with a cross-sectional design. The study sample comprised 47.233 people. The variables studied included age, sex, marital status, educational level, economic status, employment status, mass media exposure, type of residence, knowledge about HIV and AIDS, and stigma against PLWHA. The data analysis technique was the chi-square test and logistic regression with α 0.05 (5%). Result: Factors that determined the stigma of PLWHA include age 15-19 (OR 1.611), age 20-24 (OR 1.438), age 25-29 (OR 1.131), age 30-34 (OR 0.993), male gender (OR 0.834), married status (OR 1.416), educational level less (1.247), very poor economic status (OR 1.503), poor (OR, 1.134), medium (OR 1.080), rich (OR 0.972), not working ( OR 1.065), and lack of knowledge (OR 2.588). Conclusion: person aged 15-24 years, female, single, have low education, poorest/poor, do ot have a job, and have a low level of knowledge about HIV and AIDS are very likely to be stigmatized towards PLWHA. Education related to HIV and AIDS, especially how HIV and AIDS are transmitted, still needs to be improved so that it can reach all levels in society
DEVELOPMENT OF SUSTAINABLE HEALTHCARE MODEL FOR THE HOSPITALS IN NORTHERN INDIA
Authors: Gupta Hima , Garg Shweta , Gupta Utkarsh 
Published: August 2023

Background: Healthcare organizations incorporate products and services at economical prices to deliver healthcare services of good quality. All the operations performed in the organizations aimed to achieve a higher level of environmental sustainability governed by the Sustainable Developmental Goals of 2030.
Aims: This study aims to develop a sustainable healthcare model using Analytical Hierarchy Process (AHP).
Methods: First and foremost, the authors have identified the factors associated with the sustainable healthcare system through a literature review. Based on these factors, a questionnaire was developed and administered to 25 healthcare organizations from December 2020 to March 2021. An Analytical Hierarchy Process is utilized to rank the factors, and a conceptual model is developed. The Felix Hospitals substantiate this model. The authors have also applied sensitivity analysis to validate the results achieved via AHP.
Results: The AHP model demonstrates the focus is on the environment first, followed by the economic and social dimensions sustainably. The validated model was also substantiated by the hospital (Felix) results and sensitivity analysis.
Conclusion: It can be concluded that hospital sustainability highly depends on the environment in the first stage and economic and social sustainability in the second and third stages. The same result was achieved through AHP.
Keywords: analytical hierarchy process, hospital, sustainable healthcare.
COST ANALYSIS OF HOME PHARMACY CARE PROGRAM AMONG DIABETES PATIENTS IN PHARMACY
Authors: Halisa Kiftiatin Nur , Setiawan Didik , Prasuma Galar Sigit 
Published: August 2023

Background: Home pharmacy care is expected to be able to provide a pharmaceutical service that not only reduces the incidence of drug interactions and side effects but also increases the effectiveness of therapy and patient compliance in using drugs.
Aims: The study aimed to analyze the costs incurred for the home pharmacy care program for diabetic patients at the pharmacy.
Methods: This analysis used the independent variable by providing a program of home pharmacy care. The dependent variable was the cost of running the program of home pharmacy care. The sample was the pharmacist in charge of the pharmacies in the Banyumas and Cilacap districts, which provide a home pharmacy care service program. The sample was conducted by purposive sampling method. Sampling was done by direct interviews with pharmacists who signed informed consent. Break Even Point (BEP) was calculated to determine the number of patients who must be served. The pharmacoeconomic analysis used is Cost Analysis using the activity-based costing (ABC) method.
Results: The lowest rate for home pharmacy care services is Rp. 17,000, and the highest is Rp.31,000 without including home pharmacy care services.
Conclusions: Pharmacies continue to benefit from the home pharmacy care program, and there is no provision for home pharmacy care service rates.
Keywords: Activity Based Costing (ABC), Diabetes Mellitus, Home pharmacy care (HPC)
Nomophobia Sebagai Determinan Kualitas Tidur Mahasiswa Keperawatan
Authors: Riandi Irnanda Naufal , Mulyono Wastu Adi , Choiruna Hasby Pri 
Published: August 2023

Background. Sleep is a basic human need that has to be fulfilled as a fundamental of physiological part, but mostly need of sleep not fulfil enough and have a bad sleep quality. There are numerous factors that affect someone sleep quality, those are age, gadget, nomophobia, and physical activity. This research purposed to predict the most influential variable of sleep quality among nursing students.
Methods. This cross-sectional study aimed to predict the influential variable that affect sleep quality among nursing students. Regression analysis to 80 respondents that selected by simple random sampling from students batch 2019, 2020, 2021, and 2022 had done to examine the determinant of sleep quality nursing students.
Results. From four predictors that used in this research, only nomophobia (p=0,001) which had a significant correlation to sleep quality by partial t test. Simultaneous F test indicated that all variable were significantly correlated with sleep quality (p=0,004) and coefficient determination 18,1% . Simple linear regression with nomophobia and sleep quality get significant result (p=0,001) and coefficient determination 0,171.
Conclusion. Nomophobia is a determinant variable of sleep quality among nursing academic community. Sleep problem among nursing students around a fifth affected by nomophobia. It is suggested to nursing student aware of their anxiety to gadget because it might help for better sleep quality.