bluuebunny/crossref_metadata_2025_split huggingface dataset:
Virtual reality simulator for developing spatial skills during retrograde intrarenal pyeloscopy
Authors: Talyshinskii A. E. , Guliev B. G. , Mishvelov A. E. , Agagyulov M. U. , Andriyanov A. A. 
Published: April 2023

Introduction. Currently, several virtual reality (VR) simulators have been described for the upper urinary tract stone surgery skill development, including retrograde or antegrade nephroscopy. However, their high cost and the lack of a detailed reconstruction of the intraluminal pelvicalyceal system (PCS) appearance limit their implementation into educational process and clinical practice.Objectives. To develop the approach for VR-reconstruction of the intraluminal appearance of the PCS via head mounted device (HMD), as well as estimate its usefulness for novices to improve spatial orientation during retrograde flexible nephroscopy.Materials & methods. Five residents without experience in self-performing retrograde flexible nephroscopy participated in a 7-day training course on the VR simulator developed, during which each novice studied six variants of the PCS. For the procedure simulation, a silicone kidney model was created with the stone placed in the calyx which was selected randomly in each case. Before and after VR-course, each resident assisted the experienced urologist during simulated retrograde nephroscopy to find the stone placed according to random selection. The nephroscopy time and the number of errors in stone-finding during retrograde flexible nephroscopy were analysed.Results. There was a statistically significant decrease in nephroscopy time (on avg by 17.6 minutes, p = 0.043) and errors to find targeted calyx, which was observed once after the training one resident only.Conclusion. The described VR simulator does not require significant time, technical and financial costs, and is available for wide implementation in the training of young specialists.
Ejaculation-sparing enucleation of benign prostate hyperplasia: is it almost feasible?
Authors: Martov A. G. , Ergakov D. V. , Asliev K. A. , Baykov N. A. 
Published: April 2023

Introduction. Patients often request maintenance of antegrade ejaculation, and try to find the clinic, surgeon, and treatment to store it. Despite an established technique, the long-term results of ejaculation-sparing operations at a large prostate volume remain unstable. This is not allowed to give patients a guarantee in maintaining this component in their sexual life.Objective. To evaluate the frequency of ejaculation maintenance after laser ejaculatory-sparing prostate enucleation.Materials & methods. Since 2017 ejaculation-sparing laser enucleations have been performed in prostate volume (V pr > 80 cc) in 84 patients. Fifty-four patients (64%) had three lobes benign prostate hyperplasia (BPH) and two lobes — 30 patients (36%). Preoperative voiding parameters were IPSS score — 21.0 ± 2.7, QoL — 4.8 ± 0.6, residual urine volume (V res) — 139 ± 43 mL, Q max — 8.1 ± 2.0 mL. We estimate the result as positive if antegrade ejaculation remained after intervention. If ejaculation volume decreased, then as partially positive and negative — ejaculation was absent postoperatively. We conducted questionnaire and follow-up examination 3 – 6 months after intervention.Results. Thulium-fiber laser enucleations have been performed in all cases without any serious complications. Followup 3 – 6 months after operation showed V pr — 29 ± 4 cc, V res — 19 ± 17 mL, Q max — 19.1 ± 3.1 mL/sec. IPSS score — 8.1 ± 1.9 and QoL — 2.6 ± 0.7. There are the following technical remarks: 1) tissue-sparing in the verumontanum; 2) no or minor mechanical tissue tension during enucleation; 3) avoid additional resection in the bladder neck; 4) refuse total coagulation; 5) no urethral catheter tension after operation; 6) catheter balloon inflow only in the bladder, not in the fossa. Antegrade ejaculation has stored at 17 (20%) patients, partial ejaculation — at 34 (40%) patients, so overall efficacy is 60%. The presence of a median lobe is shown to be negative prognostic factor due to the absence of full antegrade ejaculation in all cases. A partial ejaculation was achieved at 21 patients. Based on the obtained results we have optimized the three-lobe prostate enucleation technique. Four from our initial 7 patients had full storage of ejaculation and 3 — partial.Conclusion. The possibility of BPH laser surgery to store ejaculation function at the request of the patients is modest. The presence of the median lobe makes the full ejaculation-sparing impossible. In cases of two lobes BPH full storage of the ejaculation was at 57% and partial at 43%, respectively. The following evaluation of the described technique is mandatory.
Bilateral percutaneous mininephrolithotripsy: simultaneous or staged approach?
Authors: Popov S. V. , Guseinov R. G. , Orlov I. N. , Perepelitsa V. V. , Pazin I. S. , Davydov A. V. , Sytnik D. A. 
Published: April 2023

Introduction. Patients with bilateral nephrolithiasis are a challenge for the treating physician. Therefore, such patients traditionally are subject to phased surgery to reduce the rate of complications. At the same time, the enhancement of endoscopic technologies and anesthesia makes it possible to perform surgical treatment of bilateral nephrolithiasis simultaneously.Objective. To evaluate the effectiveness and safety of performing simultaneous bilateral percutaneous nephrolithotripsy (PCNL).Materials & methods. The main group comprises 19 patients (avg age 45.0 ± 2.25 years) suffering from bilateral nephrolithiasis (13 men and 6 women). The control group include 20 patients (avg age 45.80 ± 2.29 years) suffering from bilateral nephrolithiasis. Main group patients underwent simultaneous bilateral mini-PCNL, control group patients — staged PCNL within two hospitalisations. The visual analogue scale (VAS) was used to assess the pain severity. Patients noted subjective pain sensations on post-op days 1 and 3. QoL indicators were assessed using the SF-36 general questionnaire, as well as the Russian-language validated version of the WISQoL questionnaire.Results. There were no statistically significant differences between the parameters (the difference between the hemoglobin before and after mini-PCNL was 12 g/l; between the serum creatinine was 18 µmol/l). There was a decrease in total surgery time (121.0 ± 6.1 min) for main group patients compared to (147.0 ± 7.3 min) control group patients (total surgery time during the first and second hospitalisations) and a reduction in hospital stay (4.50 ± 0.23 days) for main group patients compared to control group patients (10.0 ± 0.5 days). Complications observed by us in the two groups were comparable. The valuesobtained on the SF, RE and MH scales in main group patients were higher both on post-op day 1 (67.9 ± 3.39; 56.90 ± 2.85 and 63.80 ± 3.19, respectively) and post-op day 3 (86.80 ± 4.34; 83.70 ± 4.19 and 82.50 ± 4.13, respectively) compared to control group patients during the first and second hospitalizations. Statistically significant differences were also recorded according to the grades "Social functioning" and "Emotional influence" in main group patients (80.90 ± 0.26 and 82.6 ± 0.19, respectively).Conclusion. Simultaneous bilateral mini-PCNL is safe and effective in well-selected patients.
SVEAuAdIR model of COVID-19 Transmission
Authors: Nisitasari Anindhita , Rokhman Nur 
Published: April 2023

The COVID-19 pandemic that has occurred has received worldwide attention due to the rapid rate of transmission of the outbreak and the large number of deaths that occurred. The aim of this study is to build the SVEAuAdIR model , determine the transmission of COVID-19 in Indonesia by forecast the spread of the disease, and determine the effect of vaccination by looking at the basic reproduction number of SVEAuAdIR model. The results obtained from MAPE on the model are 12%. So it can be said that the SVEAuAdIR model is good for prediction models for the spread of COVID-19. The situation where there are no more individuals infected with COVID-19 is called COVID-19 disease free, thus it is predicted that Indonesia will be free of COVID-19 on October 7, 2021. The target of the Indonesian Ministry of Health is that by the end of 2021 the spread of COVID-19 can be stopped . However, on October 7, 2021, judging from the actual data during this research, there were still new cases of COVID-19. On that day there were 1393 new cases infected with COVID-19. Thus, showing that Indonesia's target of being free of COVID-19 disease by the end of 2021 has not been achieved. The number of the SVEAuAdIR model is in the range of values , which means that the spread of disease is close to disease-free. Based on the results of the value of the SVEAuAdIR model, this study concluded that vaccination could reduce the spread of COVID-19 compared to those who did not vaccinate
Penggunaan Pre-trained Model untuk Klasifikasi Kualitas Sekrup
Authors: Rafif Muhammad , Kusumaning Putri Diyah Utami , Awaludin Lukman 
Published: April 2023

Inspeksi kualitas produk berbasis citra merupakan hal yang penting bagi industri manufaktur. Tugas tersebut sebagian besar masih dilakukan oleh manusia yang memiliki unit per hour rendah. Metode konvensional untuk inspeksi citra masih mengandalkan metode berbasis fitur, yang memiliki masalah sulitnya generalisasi dan ekstraksi fitur. Masalah tersebut diatasi dengan metode CNN, tetapi CNN membutuhkan data yang besar dan waktu training yang lama. Penggunaan pre-trained model dan augmentasi citra dapat menyelesaikan permasalahan pada metode-metode sebelumnya. Namun, belum ada penelitian yang secara lengkap meneliti dan membandingkan performa berbagai pre-trained model dan variasi augmentasi citra untuk tugas inspeksi citra kualitas produk manufaktur.Proses penelitian menggunakan dataset sekrup berjenis multi class dan binary class pada 33 jenis pre-trained model dan 8 jenis augmentasi citra. Pengujian pre-trained model menggunakan dataset gabungan seluruh jenis augmentasi citra. Model dengan akurasi tertinggi adalah EfficientNetV2-L untuk dataset multi class (97.8%) dan VGG-19 untuk dataset binary class (96.5%). Augmentasi citra dengan signifikansi tertinggi terhadap performa model adalah blur, dengan akurasi 81.1% pada multi class dan 92% pada binary class. Keseluruhan proses pengujian pre-trained model dan augmentasi citra berjalan dengan baik. Kata kunci—Inspeksi kualitas produk, Pre-trained model, Augmentasi citra
Long-Term Outcomes in IgA Nephropathy
Authors: Pitcher David , Braddon Fiona , Hendry Bruce , Mercer Alex , Osmaston Kate , Saleem Moin A. , Steenkamp Retha , Wong Katie , Turner A. Neil , Wang Kaijun , Gale Daniel P. , Barratt Jonathan 
Published: April 2023

Background
IgA nephropathy can progress to kidney failure, and risk assessment soon after diagnosis has advantages both for clinical management and the development of new therapeutics. We present relationships among proteinuria, eGFR slope, and lifetime risks for kidney failure.

Methods
The IgA nephropathy cohort (2299 adults and 140 children) of the UK National Registry of Rare Kidney Diseases (RaDaR) was analyzed. Patients enrolled had a biopsy-proven diagnosis of IgA nephropathy plus proteinuria >0.5 g/d or eGFR <60 ml/min per 1.73 m2. Incident and prevalent populations and a population representative of a typical phase 3 clinical trial cohort were studied. Analyses of kidney survival were conducted using Kaplan–Meier and Cox regression. eGFR slope was estimated using linear mixed models with random intercept and slope.

Results
The median (Q1, Q3) follow-up was 5.9 (3.0, 10.5) years; 50% of patients reached kidney failure or died in the study period. The median (95% confidence interval [CI]) kidney survival was 11.4 (10.5 to 12.5) years; the mean age at kidney failure/death was 48 years, and most patients progressed to kidney failure within 10–15 years. On the basis of eGFR and age at diagnosis, almost all patients were at risk of progression to kidney failure within their expected lifetime unless a rate of eGFR loss ≤1 ml/min per 1.73 m2 per year was maintained. Time-averaged proteinuria was significantly associated with worse kidney survival and more rapid eGFR loss in incident, prevalent, and clinical trial populations. Thirty percent of patients with time-averaged proteinuria of 0.44 to <0.88 g/g and approximately 20% of patients with time-averaged proteinuria <0.44 g/g developed kidney failure within 10 years. In the clinical trial population, each 10% decrease in time-averaged proteinuria from baseline was associated with a hazard ratio (95% CI) for kidney failure/death of 0.89 (0.87 to 0.92).

Conclusions
Outcomes in this large IgA nephropathy cohort are generally poor with few patients expected to avoid kidney failure in their lifetime. Significantly, patients traditionally regarded as being low risk, with proteinuria <0.88 g/g (<100 mg/mmol), had high rates of kidney failure within 10 years.
Efectos de la privación de alimento prenatal sobre el peso corporal, consumo alimento y tasa de crecimiento durante el periodo post-privación
Authors: López-Espinoza Antonio , Martínez-Moreno Alma Gabriela , Aguilera-Cervantes Virginia Gabriela , Bernal-Gómez Samantha Josefina , Sánchez-Caballero Berenice , Mancilla-González Rocío , Santillán-Rivera Minerva Saraí 
Published: April 2023

En las diversas etapas del desarrollo, los organismos están expuestos a distintas disposiciones ambientales que tienen injerencia sobre su estado de salud, evidenciando la influencia de los patrones alimentarios sobre la aparición de enfermedades asociadas al incremento del peso corporal. No obstante, no solo ello es determinante, también las circunstancias intrauterinas en las cuales se desarrolla el organismo juegan un papel fundamental en su presencia de patologías. Un ejemplo de lo anterior son los efectos post-privación, dado que la privación de alimento genera alteraciones en el peso corporal; por lo que resulta de interés evaluar sus efectos en una etapa prenatal (i.e., la gestación). Para tal fin durante cinco fases, dieciséis ratas albinas de la cepa Wistar fueron asignadas a dos grupos (experimental y control) cada uno con 8 sujetos, fueron expuestas a condiciones de libre acceso seguidas de privación de alimento. Como condición previa al inicio del experimento las crías del grupo experimental, fueron expuestas a privación de alimento durante la gestación; mientras que las del grupo control a condiciones ad libitum durante la misma etapa. Los principales resultados muestran que los efectos post-privación se replican utilizando privación intrauterina, sin embargo, en condiciones intrauterinas aumenta la adaptación a privaciones futuras. Con base en esto, es posible señalar que la historia de privación del grupo experimental fue un importante factor que generó una adaptación ante futuras en los ciclos privación-realimentación.
Determinantes del éxito en procesos de profesionalización de empresas familiares
Authors: Llanos Orlando , Pasten Dennis , Valenzuela Dr. Fredy-Roberto , Huepe Pablo 
Published: April 2023

La profesionalización genera un alto impacto en la competitividad de las empresas, aún más en empresas familiares donde estos procesos son especialmente complejos. Esta investigación buscó determinar cuáles son los determinantes del éxito de procesos de profesionalización de empresas familiares. Sobre la base de la opinión de expertos del ámbito académico, asesoresconsultores de empresas familiares y empresarios que han vivido este tipo de procesos, se logró determinar que las variables que más explican el éxito en este tipo de procesos son la capacidad de adaptarse a los cambios y el control de los procesos de profesionalización. Por otra parte, las variables que menos explican este fenómeno son la capacidad de compartir tareas por parte del propietario y la incorporación de ejecutivos no familiares por medio de procesos competitivos. Esta investigación reafirma las variables encontradas en la literatura y adicionalmente propone un modelo factorial que las agrupa y relaciona de forma más precisa mejorando su comprensión. Futuros estudios podrían profundizar el estudio de este fenómeno, mejorando el tamaño y representatividad de la muestra y estudiando el impacto de variables como la cultura o el tipo de industria. AbstractThe professionalization creates a high impact on the business competitiveness, in particular on family businesses where these processes are particularly complex. This research aimed at identifying the determinants of success in the family businesses professionalization process. Based on the opinions of academic staff, consultants, family business’ managers and entrepreneurs who have experienced this type of process, it was determined that the variables that explain the most the success of this type of process are the ability to adapt to changes and the control of the processes. On the other hand, the variables that explain the least are the ability to share tasks by the owner and the incorporation of non-family executives through competitive processes. This research confirms the variables found in the literature and additionally proposes a factorial model that groups these variables in a more precise and understandable manner. Further studies may try to gain a better and deeper understanding of this phenomenon, improving the sample’s size and representativeness and investigating the impact of variables such as culture or the type of industry.
Comparación de la participación femenina en el mercado laboral trimestres enero - marzo 2011 y 2013
Authors: Chandía Vásquez Fernanda A. , Nazar Soto Ramón E. , Oviedo Pradenas Boris I. 
Published: April 2023

En este artículo analizamos y comparamos la participación de la mujer en el en los distintos sectores económicos, a nivel nacional y regional. Para ello utilizamos antecedentes obtenidos de la Nueva Encuesta Nacional de Empleo (NENE), las cuales fueron tabuladas y estudiadas en el periodo de enero-marzo 2011 y enero-marzo 2013. Considerando como base un acabado marco teórico, analizamos la evolución histórica de la inclusión de la mujer en el ámbito laboral. Utilizando el software SPSS se logró determinar estadísticamente, la participación de la mujer en las distintas actividades económicas del país.En base al estudio realizado se puede dilucidar, que independientemente del aumento de la participación de la mujer en el mercado laboral, sigue existiendo predominancia del sexo masculino en la mayoría de las distintas actividades económicas del país. AbstractIn this article we analyze and compare the participation of women in the diferent economic sectors, national and regional levels. We use records obtained from the New National Employment Survey, which were tabulated and studied in the period January-March 2011 and January-March 2013. Considering as a theoretical framework based finish, we analyze the historical evolution of the inclusion of women in the workplace. Using SPSS statistical software is able to determine the involvement of women in economic activities of the country.Based on the study can be performed to elucidate, that regardless of the increased participation of women in the labor market, there is still a predominance of males in most of the economic activities of the country.
International legal problems of the qualification of the right to a decent standard of living
Authors: Andriiv V. , Vakhonieva T. 
Published: April 2023

The article considers the human right to a decent standard of living, its consolidation in international legal acts on human rights, constitutions and legislation of foreign states. It is emphasized that different terminology in the constitutions of states reflects a conflicting understanding of human rights, as well as the level of their development in a specific state. In this regard, different approaches to the studied terminology are observed in modern scientific literature.
It is noted that a reliable idea of what constitutes the right to life and the right to a dignified life can be formed under the condition of synthesis of knowledge about what life is in general, as well as about the criteria of its dignity. The opinion expressed is that social and legal criteria for a dignified human life represent a multi-component open system. The level of self-realization of a person, acting in this system as an integral, system-creating criterion, is concretized into certain, quite important components: which make it possible to assess the sufficiency of material goods necessary to ensure the real possibility of realizing individual interests and needs; the sufficiency of intangible goods necessary to ensure the realization of individual interests and needs; legal guarantee and protection of the right to a dignified life.
It was emphasized that the level of realization of the right to a decent life is influenced by various factors: state social policy, level of development of the social sphere in the country, living conditions of the population, lifestyle, investment climate, state of the environment, spirituality, socio-historical processes, income of the population, poverty and inequality, unemployment and labor force utilization, demographic dynamics, education and training, health, food and nutrition, housing conditions, infrastructure, communication, culture, social ties, family values, political and social stability, political and civil institutions.
Based on the analysis of scientific points of view and legislation, the author comes to the conclusion that the right to a decent standard of living as a legal category is the minimum standard for satisfying human needs in various spheres: from physiological to spiritual. It includes social, economic and political rights that allow a person to be a worthy member of society, to develop freely in the conditions of security and social protection of the state. This right is enshrined in all the main international acts, both universal and regional, which define basic human rights and freedoms.
THE EFFECT OF CAPITAL STRUCTURE, CAPITAL INTENSITY AND COMPANY SIZE ON CORPORATE INCOME TAX IN THE PHARMACEUTICAL SUBSECTOR LISTED ON THE IDX FOR THE PERIOD 2016 – 2021
Authors: Mustika Vina , Sofyah Susan , Silvia Silvia 
Published: April 2023

This study aims to determine and verify the effect of capital sturcture, capital intensity and firm size in pharmaceutical company listed on Indonesia Stock Exchange in 2016 – 2021 with purposive samping technique obtain a sample of samples used in this research is panel data regression using E-Views 9.0 Variable in this study is corporate income tax for dependent variable and capital structure, capital intensity and firm size for independent variable. The result of the study indicate that capital structure has no effect on corporate income tax, capital intensity has a positive effect on on corporate income tax and firm size has a positive effect on corporate income tax.
Keyword : Income Tax, DER, CIR , SIZE