bluuebunny/crossref_metadata_2025_split huggingface dataset:
СОЦІАЛЬНО-ПСИХОЛОГІЧНА АДАПТАЦІЯ ЗДОБУВАЧІВ ВИЩОЇ ОСВІТИ ПОЛТАВСЬКОГО ДЕРЖАВНОГО МЕДИЧНОГО УНІВЕРСИТЕТУ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Іленко Н. М. , Бойченко О. М. , Іленко-Лобач Н. В. 
Published: September 2023

Анотація. Соціально-психологічна адаптація – це процес подолання проблемних ситуацій особистістю, в ході якого вона використовує набуті на попередніх етапах свого розвитку навички соціалізації, що дозволяє їй взаємодіяти з групою без внутрішніх або зовнішніх конфліктів, продуктивно виконувати провідну діяльність, виправдовувати рольові очікування і, при цьому, самостверджуватись, задовольняти свої основні потреби. Життя людини тісно пов’язане з її професійною діяльністю, тому немає нічого більш важливого, аніж правильний вибір життєвого шляху та майбутньої діяльності. Для реалізації кожної людини, як соціального елементу, необхідно знайти своє місце в соціумі, що в подальшому дозволить реалізувати себе повною мірою, відчути радість від праці, яку виконуєш.
Процес адаптації особистості здобувачів до освітнього процесу в умовах воєнного стану – довгий і складний, а часом навіть дуже проблематичний. Він характеризується повною відмовою від звичного способу життя та входженням у нове невідоме доросле життя, в якому необхідно думати не тільки про навчання, а й про те, як вижити під час війни, убезпечити себе та своїх рідних, допомогти армії та країні.
Сьогодні колектив кафедри терапевтичної стоматології ПДМУ працює в офлайн-, змішаному та онлайн-режимі (на платформі Zoom). Змішана форма навчання складається з трьох ключових компонентів, таких, як: лекції, практичні заняття та безпосереднє спілкування викладача зі здобувачами (індивідуальна робота). Наразі лекційний матеріал представлений у формі презентацій та коротких конспектів усіх лекцій на сайті кафедри. Що ж до практичних занять, то тут також є зміни: передусім викладачі приділяють час психолого-педагогічній підтримці студентів, адже військові дії, повітряні тривоги та перманентний тривожний стан перешкоджають відчуттю «базової безпеки», необхідної для ґрунтовного засвоєння навчального матеріалу. За сприятливих умов (відсутність повітряних тривог та відключень електроенергії) значно збільшується час на опанування практичних навичок (робота з пацієнтами), щоб компенсувати недоліки виключно дистанційного навчання на початку війни. Викладачі кафедри індивідуально підходять до оцінювання кожного студента, адже сьогодні вони можуть готуватися до заняття в умовах тривалої відсутності світла, Інтернету, мобільного зв’язку.
Успішна соціально-психологічна адаптація до освітнього процесу в умовах воєнного стану забезпечує подальший розвиток здобувача освіти як особистості та майбутнього професіонала. Від того, наскільки швидко та ефективно здобувачі освіти подолають перешкоди в ході оволодіння професійними компетенціями, залежить, як вони реалізують свої здібності у сфері професійної діяльності та поза нею. В подальшому розвитку проблеми соціально-психологічної адаптації здобувачів планується розробити шляхи вирішення та вдосконалення методичних напрацювань, що надасть можливість кращого сприйняття ситуації в даний час.
MillenniumDB: An Open-Source Graph Database System
Authors: Vrgoč Domagoj , Rojas Carlos , Angles Renzo , Arenas Marcelo , Arroyuelo Diego , Buil-Aranda Carlos , Hogan Aidan , Navarro Gonzalo , Riveros Cristian , Romero Juan 
Published: September 2023

ABSTRACT
In this systems paper, we present MillenniumDB: a novel graph database engine that is modular, persistent, and open source. MillenniumDB is based on a graph data model, which we call domain graphs, that provides a simple abstraction upon which a variety of popular graph models can be supported, thus providing a flexible data management engine for diverse types of knowledge graph. The engine itself is founded on a combination of tried and tested techniques from relational data management, state-of-the-art algorithms for worst-case-optimal joins, as well as graph-specific algorithms for evaluating path queries. In this paper, we present the main design principles underlying MillenniumDB, describing the abstract graph model and query semantics supported, the concrete data model and query syntax implemented, as well as the storage, indexing, query planning and query evaluation techniques used. We evaluate MillenniumDB over real-world data and queries from the Wikidata knowledge graph, where we find that it outperforms other popular persistent graph database engines (including both enterprise and open source alternatives) that support similar query features.
The Orthodox Woman: Jerome on the Relation Between Asceticism, Orthodoxy, and Gender
Authors: Pålsson Katarina 
Published: September 2023

Abstract
While previous scholarship has shown that the rhetorical figure of the “heretical woman” was important in Jerome’s slandering of male rivals, this article argues that the “orthodox woman” played a just as important role in his self-presentation as an orthodox teacher. The “orthodox woman” is characterized by true asceticism which, according to Jerome’s ascetic theology, implies that she transcends her sex. Rather than being a “woman”, in the ordinary sense of the word, she is an angelic being with a supernatural understanding, which allows her to discern the spiritual meaning of the Scriptures and to distinguish between orthodoxy and heresy. It is argued that the presentation of the “orthodox woman” as very learned, independent and strong-willed makes her the direct opposite of Jerome’s “heretical woman”, and that such a portrayal suited Jerome’s purposes, as his great reliance on women readers called for a defence of female spiritual authority.
Diverging Global Dry and Humid Heat Responses to Modern Irrigation
Authors: Chiang Felicia , Cook Benjamin I. , McDermid Sonali 
Published: September 2023

Abstract
The moderating influence of irrigation on dry heat extremes is well established, but the effect of irrigation on humid heat is more uncertain. Here, we study the impact of modern irrigation on both dry and humid heat-wave occurrences during the boreal summer using the NASA GISS Earth System Model (ModelE) with and without present-day irrigation. We show that the presence of modern irrigation reduces the total number of dry heat waves in most land areas, especially in arid and temperate regions. In contrast, humid heat waves occur more frequently under modern irrigation, especially in the Mediterranean Sea region, northern Africa, southern Africa, and the Middle East. Present-day irrigation reduces dry heat extremes by favoring latent heating over sensible heating and lowering surface solar radiation by increasing total cloud cover. Meanwhile, modern irrigation drives increases in humid heat through increases in specific humidity and precipitation. Notably, the reduction in dry heat is mostly localized over irrigated grid cells while humid heat increases both in locally irrigated areas and remote (nonirrigated) regions because of widespread increases in humidity associated with irrigation. Our results suggest that irrigation may amplify humid heat, even in nonirrigated areas, highlighting the importance of improving our understanding of both local and remote effects of the irrigation forcing on climate hazards.
Diverse Eurasian Temperature Responses to Arctic Sea Ice Loss in Models due to Varying Balance between Dynamic Cooling and Thermodynamic Warming
Authors: Zheng Cheng , Wu Yutian , Ting Mingfang , Screen James A. , Zhang Pengfei 
Published: September 2023

Abstract
Cold winters over Eurasia often coincide with warm winters in the Arctic, which has become known as the “warm Arctic–cold Eurasia” pattern. The extent to which this observed correlation is indicative of a causal response to sea ice loss is debated. Here, using large multimodel ensembles of coordinated experiments, we find that the Eurasian temperature response to Arctic sea ice loss is weak compared to internal variability and is not robust across climate models. We show that Eurasian cooling is driven by tropospheric and stratospheric circulation changes in response to sea ice loss but is counteracted by tropospheric thermodynamical warming, as the local warming induced by sea ice loss spreads into the midlatitudes by eddy advection. Although opposing effects of thermodynamical warming and dynamical cooling are found robustly across different models or different sea ice perturbations, their net effect varies in sign and magnitude across the models, resulting in diverse model temperature responses over Eurasia. The contributions from both tropospheric dynamics and thermodynamics show substantial intermodel spread. Although some of this spread in the Eurasian winter temperature response to sea ice loss may stem from model uncertainty, even with several hundred ensemble members, it is challenging to isolate model differences in the forced response from internal variability.
Assessment of an Experimental Version of fvGFS for TC Genesis Forecasting Ability in the Western North Pacific
Authors: Lin Shu-Jeng , Hsu Huang-Hsiung , Tu Chia-Ying , Chih Cheng-Hsiang 
Published: September 2023

Abstract
We evaluated the ability of the fvGFS with a 13-km resolution in simulating tropical cyclone genesis (TCG) by conducting hindcast experiments for 42 TCG events over 2018–19 in the western North Pacific (WNP). We observed an improved hit rate with a lead time of between 5 and 4 days; however, from 4- to 3-day lead time, no consistent improvement in the temporal and spatial errors of TCG was obtained. More “Fail” cases occurred when and where a low-level easterly background flow prevailed: from mid-August to September 2018 and after October 2019 and mainly in the eastern WNP. In “Hit” cases, 850-hPa streamfunction and divergence, 200-hPa divergence, and genesis potential index (GPI) provided favorable TCG conditions. However, the Hit–Fail case differences in other suggested factors (vertical wind shear, 700-hPa moisture, and SST) were nonsignificant. By contrast, the reanalysis used for validation showed only significant difference in 850-hPa streamfunction. We stratified the background flow of TCG into four types. The monsoon trough type (82%) provided the most favorable environmental conditions for successful hindcasts, followed by the subtropical high (45%), easterly (17%), and others (0%) types. These results indicated that fvGFS is more capable of enhancing monsoon trough circulation and provides a much better environment for TCG development but is less skillful in other types of background flow that provides weaker large-scale forcing. The results suggest that the most advanced high-resolution weather forecast models such as the fvGFS warrant further improvement to properly simulate the subtle circulation features (e.g., mesoscale convection system) that might provide seeds for TCG.

Significance Statement
This study provides an evaluation of tropical cyclone genesis prediction skill of fvGFS. Favorable large-scale environmental factors for successful prediction are identified. Skill dependence on environmental factors provides guidance for evaluating the reliability of a genesis forecast in advance.
A Visual-Vestibular Model to Predict Motion Sickness for Linear and Angular Motion
Authors: Sousa Schulman Daniel , Jalgaonkar Nishant , Ojha Sneha , Rivero Valles Ana , Jones Monica L. H. , Awtar Shorya 
Published: September 2023

Objective This study proposed a model to predict passenger motion sickness under the presence of a visual-vestibular conflict and assessed its performance with respect to previously recorded experimental data. Background While several models have been shown useful to predict motion sickness under repetitive motion, improvements are still desired in terms of predicting motion sickness in realistic driving conditions. There remains a need for a model that considers angular and linear visual-vestibular motion inputs in three dimensions to improve prediction of passenger motion sickness. Method The model combined the subjective vertical conflict theory and human motion perception models. The proposed model integrates visual and vestibular sensed 6 DoF motion signals in a novel architecture. Results Model prediction results were compared to motion sickness data obtained from studies conducted in motion simulators as well as on-road vehicle testing, yielding trends that are congruent with observed results in both cases. Conclusion The model demonstrated the ability to predict trends in motion sickness response for conditions in which a passenger performs a task on a handheld device versus facing forward looking ahead under realistic driving conditions. However, further analysis across a larger population is necessary to better assess the model’s performance. Application The proposed model can be used as a tool to predict motion sickness under different levels of visual-vestibular conflict. This can be leveraged to design interventions capable of mitigating passenger motion sickness. Further, this model can provide insights that aid in the development of passenger experiences inside autonomous vehicles.
Predicting clozapine dose required to achieve a therapeutic plasma concentration – A comparison of a population algorithm and three algorithms based on gene variant models
Authors: Taylor David , Cahill Caroline , Wallang Paul , Millard Louise , Cela Luis Ramudo , Breen Kieran C 
Published: September 2023

Background: Clozapine is the most effective antipsychotic but requires careful titration to therapeutic blood levels. Methods to predict therapeutic doses are based on population data. Aims: We aimed to construct a model based on genetic variants which accurately predicted plasma levels for clozapine. Method: We measured clozapine plasma levels in patients on a stable dose of clozapine who were known to be fully compliant. Measured plasma levels were adjusted for sampling time and dose. Hepatic enzyme variants were analysed and models were constructed to predict the required dose. These predictions were compared with a standard population-based algorithm. Results: We measured plasma clozapine concentrations in 18 adherent patients on stable doses of clozapine and recorded the exact timing of sampling. For the algorithm-predicted dose, the mean difference was −49.9 mg/day ((SD 155.9), r = 0.36) from the actual dose required to give a plasma concentration of 0.35 ng/ml. The gene variant activity score predicted a dose for which the mean difference was −43.5 mg/day ((SD 140.1), r = 0.55). For the gene variant activity score with omeprazole correction predicted dose, the mean difference was −31.0 mg/day ((SD 140.8), r = 0.54), and with the gene variant CYP1A2 inducibility predicted dose the mean difference was 44.9 mg/day ((SD 160.8), r = 0.32). Conclusion: Our gene variant activity score with omeprazole correction gave the best estimate of the clozapine dose required to achieve a minimum therapeutic plasma concentration. The use of this model will allow safer titration of clozapine and may reduce the need for plasma-level monitoring during titration.
Effect of valve leaflet surface patterning on valve hydrodynamic performance
Authors: Wang Aili , Wang Yumiao , Liu Wanbing , Liu Li , Zhou Jianye 
Published: September 2023

Objective: We aimed to elucidate the effects of the micro-structure of the pyrolytic carbon for artificial heart valves on its hydrodynamic performance. Methods: Bileaflet mechanical valves of GKS 23 and 29 A were randomly selected. According to ISO5840, mean transvalvular pressure (MPG), regurgitation fraction (RF), and effective orifice area (EOA) of valve were assessed. Then, parallel-groove pattern was constructed by laser etching on leaflet surface, and the valves were subjected again to the same test. Results: Compared with before patterning at 2, 3.5, 5, and 7 L/min, the MPG of the valves in two specifications were higher, the EOA was larger in 23 A, but smaller in 29 A, and the RF was contrary to EOA. At 5 L/min, the RF in both specifications was lower after etching at 45 bpm. At 70 bpm however, the RF in 23 A decreased, in 29 A increased. Conclusion: The parallel-groove pattern on leaflet surface affected the hemodynamic performance of the valve prostheses.
Activation of GPR81 aggravated intestinal ischemia/reperfusion injury-induced acute lung injury via HMGB1-mediated neutrophil extracellular traps formation
Authors: Yili Sun , Xinyi Dai , Kerui Fan , Kun Chen , Yang Yongqiang , Zhang Li , Hu Kai 
Published: September 2023

Introduction Intestinal ischemia/reperfusion (II/R) injury is a life-threatening situation accompanied by severe organ injury, especially acute lung injury (ALI). A great body of evidence indicates that II/R injury is usually associated with hyperlactatemia. G-protein-coupled receptor 81 (GPR81), a receptor of lactate, has been recognized as a regulatory factor in inflammation, but whether it was involved in II/R injury-induced ALI is still unknown. Methods To establish the II/R injury model, the superior mesenteric artery of the mice was occluded gently by a microvascular clamp for 45 min to elicit intestinal ischemia and then a 90-min reperfusion was performed. Broncho-alveolar lavage fluid (BALF) and lung tissues were obtained to evaluate the lung injury after II/R. The pulmonary histopathological alteration was evaluated by H&E staining. The concentration of proteins, the number of infiltrated cells, and the level of IL-6 were measured in BALF. The formation of neutrophil extracellular traps (NETs) was evaluated by the level of double-stranded DNA (dsDNA) and myeloperoxidase- double-stranded DNA (MPO-dsDNA) complex in BALF, and the content of citrullinated histone H3 (Cit-H3) in lung tissue. The level of HMGB1 in the BALF and plasma was measured by enzyme linked immunosorbent assay (ELISA). Results Administration of the GPR81 agonist 3,5-dihydroxybenzoic acid (DHBA) aggravated II/R injury-induced lung histological abnormalities, upregulated the concentration of proteins, the number of infiltrated cells, and the level of IL-6 in BALF. In addition, DHBA treatment increased the level of dsDNA and MPO-dsDNA complex in BALF, and promoted the elevation of Cit-H3 in lung tissue and the release of HMGB1 in BALF and plasma. Conclusion After induction of ALI by II/R, the administration of DHBA aggravated ALI through NETs formation in the lung.
Quality of life, fatigue, sleep quality, and mental health in systemic lupus erythematosus patients with a high cardiovascular risk profile
Authors: Caruso Mazzolani Bruna , Infante Smaira Fabiana , Mendes Sieczkowska Sofia , Romero Marina , Toledo Ribeiro Thainá , Cordeiro Amarante Milla , Pasoto Sandra , de Sá Pinto Ana Lúcia , Rodrigues Lima Fernanda , Braga Benatti Fabiana , Bonfa Eloísa , Roschel Hamilton , Gualano Bruno 
Published: September 2023

Systemic lupus erythematosus (SLE) patients report worse health-related quality of life (HRQL), fatigue, anxiety, depression, and sleep quality, when compared to the general population and other chronic diseases. Furthermore, cardiometabolic diseases are highly prevalent in SLE and are also associated with these parameters. Thus, it is plausible to suggest that SLE patients with a high cardiovascular risk may report worse results for these parameters. The aim of the study is to describe HRQL, fatigue, anxiety and depression symptoms, and sleep quality in a sample of SLE patients with a high cardiovascular risk profile (i.e., BMI between 25 and 40 kg/m2 and/or dyslipidemia, hypertension, or diabetes). This was a cross-sectional study where patients were assessed for (i) demographic, anthropometric, and disease-related parameters, (ii) HRQL, (iii) fatigue, (iv) anxiety and depression symptoms, and (v) sleep quality. One-hundred patients completed the study; however, only 87 patients were assessed for sleep quality data. Patients averaged 41.7 ± 9 years, and most patients were classified as overweight/obese (87%). SF-36 scores for physical and mental components summary were 51.3 ± 9.6 and 54.2 ± 15.6, respectively, with “bodily pain” and “role emotional” presenting the lower scores. The total SLEQOL score was 105.1 ± 42.0, with lower scores reported for “self-image” and “mood.” Fatigue score was 30.8 ± 8.9, and 78% and 93% reported severe symptoms of anxiety and depression, respectively. The average sleep effectiveness was 82.9 ± 6.6%. Sleep latency, total time in bed (TTiB), and total sleep time (TST) were 8.4 ± 8.9, 495.8 ± 79.7, and 409.7 ± 69.9 min, respectively. Patients reported an average of 17.8 ± 6.2 WE, with 4.5 ± 1.5 min duration and a WASO of 77.7 ± 36.6 min. Despite similar HRQL, fatigue, and sleep quality parameters to those reported by other SLE populations, SLE patients with a high cardiovascular risk had a higher prevalence of depression and anxiety. Understanding SLE patients’ quality of life and psychological symptoms is of utmost importance to improve disease management. The findings of this study highlight the need for more intensive and global care regarding mental health when considering a high cardiovascular risk in SLE.
Orthopaedic surgery academic productivity – how do we measure up?
Authors: Croker Nicholas , Panwar Yash , Balogh Zsolt J 
Published: September 2023

Purpose Research is vital for evidence-based surgery. Understanding scientometric differences among surgical specialties has scope to inform discussions within and across surgical specialities to develop and maintain a culture of research productivity. This study aims to quantify Australian orthopaedic surgical academic productivity compared to the other specialties within the Royal Australasian College of Surgeons’ (RACS). Methods A list of Australian surgeons registered with RACS was compiled using the “find a surgeon” function on the RACS Web site. This list was cross-referenced with the specialty databases on their respective websites. A name search of the SCOPUS database for each individual surgeon was performed. For each individual h-index, m-index, total active publishing years, total publications, and total citations were collected. Results Orthopaedic surgeons had the equal lowest h-index median 2 (interquartile range:3), the shortest duration involved in research median 5 years (14), produced the fewest articles median 2 (7) and attained the second lowest number of citations median 28 (116) of the Australian surgical specialties. When the 10 individuals with highest h-index are compared among specialties, orthopaedic surgeons rank second with a median of 37 (6.5). Conclusion Our objective data provides a factual comparison and baseline assessment of one aspect of research productivity. It can challenge currently held perceptions of performance and can inform conversations about strategic development. We recommend this assessment to other international Colleges and Societies on regular basis. These accurate academic productivity metrics provide opportunity for developing and maintaining a culture of sustained, significant contribution to surgical research.