bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristic Analysis of Fingerprint Datasets from a Pragmatic View of Indoor Localization using Machine Learning Approaches
Authors: Mallik Manjarini , Chowdhury Chandreyee 
Published: January 2023

Abstract
Due to their availability on commercial smartphones, WiFi, Bluetooth, and magnetometer are commonly utilized for indoor localization as indoor spaces are GPS deprived. Indoor localization falls into the category of data-intensive applications. In this domain, most of the recent solution approaches deploy MachineLearning (ML) and Deep Learning (DL) techniques on the data collected through the sensors. However, the publicly available benchmark datasets on indoor localization suffer from certain issues requiring complicated and customized data preprocessing techniques for each dataset for applying a common ML/DL technique. Thus, a fair comparison of the ML/DL methods for indoor localization datasets and hence, checking for the generality of a solution that spans across different indoor regions become infeasible. In this comparative study, we have investigated three key challenges of fingerprint datasets that should be addressed for real-life localization applications, namely, (i) repetitive site survey, (ii) device heterogeneity, (iii) granularity, and subregion-specific performance variation. To demonstrate how these attributes might impact localization performance, experimental analysis is done using five benchmark datasets. The novelty of the work is that it not only highlights the challenges but also analyse the feasibility of possible future directions to address these challenges through implementation results. Formulating the application of a generative adversarial network (GAN) to address the issue of repetitive site surveys has been discussed with implementation results.
Association mapping of rapid visco analyzer traits
Authors: zhu cheng 
Published: January 2023

Abstract
The viscous coefficient and amylose content are the important target for evaluating rice cooking and eating quality. In this study we got the genome-wide association analysis results of amylose content (AC) and parameters value of starch rapid visco analyzer (RVA) PKV, HPV, CPV, BDV, SBV, CSV, GT and PeT through 179 rice core germplasm materials. We detected 170 associated QTL locus all of the nine characters, including a number of the same QTL locus of control multiple traits on chromosome 1, 2, 5, 6, 7, 9 and 12. About 21 QTL locus have been reported related to starch synthesis genes in rice. Starch synthase (include straight-chain starch synthase genes (GBSS) and branched chain starch synthase genes(SS)) had effect on all traits. And three materials of NIP/ZS97 CSSL single segment, one material of ACC9/ZS97 CSSL single segment and one material of NIP/9311 CSSL single segment could confirm nine QTLs which effect on BDV, SBV, PKV and CSV were scanned by association analysis on chromosome 1、3、7 and 8. In the start stage of starch synthesis, participate in the regulation of glucose − 6 - phosphate (Glc6p) →glucose − 1 - (Glc1p) and phosphate Glc1p →UDPGlc way's gene GPT and PGM had a specificity effect on the traits of BDV and SBV, but had little effect on other traits.
The effect of pairing assistance under medical alliance policy on healthcare utilization for patients with chronic diseases in rural China
Authors: Li Mingyue , Zhu He , Tang Haoqing , Cheng Xiaoran , Liu Xiaoyun 
Published: January 2023

Abstract
Pairing assistance (PA) of health professionals between county hospitals and township health centers is one of the key components of the reform of medical alliances in China to strengthen the development of health workforce in primary health care (PHC). This study aims to examine the effect of PA on healthcare utilization for patients with chronic diseases in rural areas. Two waves of National Health Services Survey (2013 and 2018) were used. A total of 13893 and 22725 rural residents with chronic diseases were included in the 2013 and 2018 waves, respectively. Multiple logistic regressions were used to examine the associations between PA and outpatient and inpatient service utilization in PHC. Chow test was used to examine the difference between PA in two models. Among rural patients with chronic diseases, two-week outpatient visits increased from 22.69–27.54%, and annual hospitalization admission increased from 20.72% in 2013 to 25.44%. PA was associated with a significant decrease in outpatient visits (p < 0.001) in 2018 after controlling for individual and county characteristics. Patients in PA counties were 1.45 times (95% CI 1.10–1.90) more likely to use PHC outpatient care in 2013, but the difference disappeared in 2018 (OR = 0.85, 95% CI 0.71–1.01). PA did not reverse the downward trend in the share of PHC outpatient visits. PA under medical alliances in China provides a potential model for building integrated people-centered health systems for other low- and middle-income countries.
Comparison of staged LLIF combined with posterior instrumented fusion and posterior instrumented fusion alone for adult degenerative lumbar scoliosis with sagittal imbalance
Authors: Lai Oujie , Li Hao , Chen Qixing , Hu Yong , Chen Yunling 
Published: January 2023

Abstract
Background
To retrospectively compare the clinical and radiological results of staged lateral lumbar interbody fusion (LLIF) combined with posterior instrumented fusion（PIF）and PIF alone for adult degenerative lumbar scoliosis (ADLS) with sagittal imbalance.
Methods
ADLS patients with sagittal imbalance underwent corrective surgery were divided into staged group (multilevel LLIF at the first stage and PIF at the second stage) and control group (PIF alone). The clinical and radiological outcomes were evaluated and compared between the two groups.
Results
Forty-five patients with average age of 69.7±6.3 years were enrolled, including 25 in staged group and 20 in control group. Compared with preoperative values, both groups achieved significant improvement in terms of ODI, VAS back, VAS leg and spinopelvic parameters after surgery, which were well maintained during the follow-up period. Compared with control group, staged group showed more operative time, however, less blood loss and blood transfusion. The average posterior fixation segments were 6.2±1.78 in staged group and 8.25±1.16 (P<0.01), respectively. Posterior column osteotomy (PCO) was performed in 9 patients (36%) in staged group. PCO and/or pedicle subtraction osteotomy were performed in 15 patients (75%) in control group (P<0.01). No difference was observed between the two groups regarding complication.
Conclusion
Both surgical strategies were effective treatments for ADLS with sagittal imbalance. However, staged treatment was more minimal invasive. The first stage LLIF could simplified second stage posterior procedure, reducing the number of posterior fixation segments and osteotomy requirement.
High expression of TLR2 influenced immune infiltration in pancreatic cancer
Authors: Liu Jinyang , He Miao 
Published: January 2023

Abstract
Purpose
Pancreatic cancer showed specific immunological microenvironment. For a better understanding of relative valuable biomarkers, correlation between prognostic differentially expressed immunity genes and immunological microenvironment in online pancreatic cancer datasets was evaluated.
Methods
ssGSEA algorithm was used to evaluate the immunological characteristics in tumor samples. Limma algorithm was used to assess the differentially expressed genes, survival analysis was performed by Cox models and Kaplan Meiers method, gene sets enrichment analyses were conducted to evaluate the correlation between prognostic differentially expressed genes expression and GO/KEGG terms. ESTIMATE and CIBERSORT algorithms were used to evaluate the immune infiltration in tumor immunological microenvironment. Receiver operating characteristic analysis was performed to evaluate the diagnostic and prognostic value of prognostic differentially expressed genes in pancreatic cancer patients.
Results
High immune infiltration was demonstrated to be related with poor prognosis in pancreatic cancer. Four genes including TLR2 were identified as prognostic differentially expressed immunity genes in pancreatic cancer, high TLR2 expression was correlated with high infiltration and poor prognosis, furthermore, TLR2 expression was correlated with opposite survival in early/advanced stages. High TLR2 expression was correlated with immune-related pathways, functions and processes and indicated high immune infiltration of immune cells including activated memory CD4+ T cells, M2 macrophages and rested dendritic cells and low immune infiltration of regulatory T cells, activated natural killer cells and plasma cells. Moreover, TLR2 showed a moderate predictive accuracy in the diagnosis of pancreatic cancer.
Conclusion
Correlation between TLR2 and immune infiltration in pancreatic cancer was identified.
The theory of sandy land soil hydrology and mode of low coverage afforestation in northwest China
Authors: Wang Mingyuan 
Published: January 2023

Abstract
Most of the sandy land areas in northwest China belong to semi-arid area and the average annual rainfall is about 250-500 mm. Sandy land has the potential to reverse itself when man-made pressure is removed. The specific permeability structure of sandy soil showed heterogeneous anisotropy in the horizontal direction (x or y) of the soil surface (0-10cm), and showed interlayer homogeneity and isotropy in the vertical direction (z) of the underlying of soil surface, which formed rainfall infiltration process of the special combination of both channel flow and capillary flow percolation systems in sandy soil. It is reflected in the combination structure of "source" and "reservoir" in the soil water profile due to lateral gravity water recharge. There is no hydraulic relation between large area exposed sandy land and groundwater, and the modelof shrub community consuming soil water reflects the relationship between soil water deficit and free gravity water recharge in sandy land formed by precipitation. On the one hand, sandy land afforestation preserves a part of bare sandy land intermittently to gather surface and subsurface soil runoff (or called collecting internal drainage from source), and adopting sandy land afforestation methods and techniques with low coverage and patch vegetation configuration. On the other hand, shrub plants in sandy land have a higher root-shoot ratio. According to the balance between soil water storage (collection) and vegetation water consumption, plantation vegetation coverage in sandy land can be determined by the square of root-shoot ratio . This formula indicates that the deep roots and horizontal ductility of plants in sandy land expand the soil water space available to vegetation under drought conditions so that the water consumption of transpiration is relatively supplemented. These two aspects are the key to the success of large-scale desertification control and afforestation.
A cross-sectional study on depression and its associated factors among adults in urban Can Tho, Vietnam
Authors: Phuc Lam Duong , Ho Nhan The 
Published: January 2023

Abstract
Background
This study set out to determine the prevalence of depression and its associated factors in Can Tho City, Vietnam's urban community.
Methods
A cross-sectional descriptive study with a sample of 449 people aged 18 to 60 years old was conducted in Ninh Kieu district, Can Tho city, from September 2015 to June 2016. Depression was measured using the PQH-9 Patient Health Scale. The total PHQ-9 scores ranged from 0 to 27. Scores of 5, 10, 15, and 20 represent cut-off scores for mild, moderate, and major depression, respectively. and analyze related factors by multivariable logistic regression.
Results
Sixteen percent of participants met the cutoff point for depression, a score of 5 or over. There were 12.2% with mild depression, 2.9% with moderate depression, 0.7% with moderately severe depression, and 0.2% with severe depression. Chronic diseases (OR = 2.79; p = 0.005), introversion/affectivity (OR = 3.12; p = 0.002), failure in work or study (OR = 4.40; p <0.001), family history of mental illness (OR = 8.93; p = 0.029), family unhappiness (OR = 5.61; p = 0.002), and relatives dying or suffering from severe illness (OR = 2.75; p = 0.004).
Conclusion
This study provides an alarming signal for health professionals and health policymakers in Can Tho City about the need for better recognition of depression and its associated factors in adult people.
A Brief Questionnaire for Measuring Alarm Fatigue in Nurses and Physicians in Intensive Care Units
Authors: Wunderlich Maximilian Markus , Amende-Wolf Sandro , Krampe Henning , Kruppa Jochen , Spies Claudia , Weiß Björn , Memmert Belinda , Balzer Felix , Poncette Akira-Sebastian 
Published: January 2023

Abstract
Background. When exposed to hundreds of medical device alarms per day, intensive care unit (ICU) staff can develop “alarm fatigue” (i.e., desensitisation to alarms). However, no standardised way of quantifying alarm fatigue exists.
Objective. We aimed to develop a brief questionnaire for measuring alarm fatigue in nurses and physicians.
Methods. After developing a list of initial items based on a literature review, we conducted 15 cognitive interviews with the target group (13 nurses and two physicians) to ensure that the items are face valid and comprehensible. We then asked 32 experts on alarm fatigue to judge whether the items are suited for measuring alarm fatigue. The resulting 27 items were sent to nurses and physicians from 15 ICUs of a large German hospital. We used exploratory factor analysis to further reduce the number of items and to identify scales.
Results. A total of 585 submissions from 707 participants could be analysed (of which 14% were physicians and 64% were nurses). The simple structure of a two-factor model was achieved within three rounds. The final questionnaire (called Charité Alarm Fatigue Questionnaire; CAFQa) consists of nine items along two scales (i.e., the “alarm stress scale” and the “alarm coping scale”).
Conclusion. CAFQa is a brief questionnaire that allows clinical alarm researchers to quantify the alarm fatigue of nurses and physicians. It should not take more than five minutes to administer.
New insights of the pharmacological properties of curcumin: cytotoxicity and immuno-modulation study
Authors: Derguine Rania , Rezgui Abdelmalek , Tachour Rechda Amel , Khenchouche Abdehalim , Cherif Djaouida , Rym Agred , Meziti Hicham , Hareiche Mohammed ,   Amina Lamouri1, Bouriche hamama , Benguerba Yacine , Sobhi Widad 
Published: January 2023

Abstract

The current study aims to appreciate curcumin’s anti-inflammatory and immuno-modulation properties through the investigation of its effect on the neutrophil enzymes (MPO and elastase) activities. The toxicity of pure curcumin was studied using three cell types: human neutrophils, NOD mouse Langerhans β cell line (NIT-1), and mouse breast cancer carcinoma cell line (EMT-6). Neutrophil isolation from whole blood was assessed using the histopaque gradient density method. After the MPO and elastase extraction from isolated neutrophils, the modulatory effect of curcumin on the activity of these enzymes was assayed using 3,3′,5,5′- tétramethylbenzidine and le N-Methoxy-Suc-(Ala)2-Pro-Val-p-Nitroanilide as specific substrates, respectively. Also, the Cytotoxic of curcumin was investigated on the EMT6, NIT-1, and neutrophils cells using XTT and trypan blue exclusion assays, respectively. Results indicate that curcumin modulates the neutrophil's activity by inhibiting its enzymes. In effect, curcumin exerts a significant dose-dependent inhibitory effect on both MPO and elastase activities with IC50 of 14.41± 1.74 μg/ml and 6.06± 3.67 μg/ml. On the other hand, we reveal that curcumin significantly decreases neutrophil viability in a dose-dependent manner with IC50 = 25.60 ± 7.88 μg/ml. Moreover, no significant cytotoxic effect on EMT6 and NIT-1cells lines was shown. The IC50 of EMT6 breast cancer cell and NIT-1cell lines were higher than 30 μg/ml and 60 μg/ml, respectively. While, doxorubicin, an anti-cancer drug used as a positive control, significantly reduces EMT6 viability with IC50 of 4.885± 0.063 μg/ml. These results indicate that curcumin has a potential anti-inflammatory effect considering neutrophil viability and some of its activities. Moreover, curcumin has shown selective cytotoxicity toward neutrophils with no prominent cytotoxic effect on EMT6 and NIT-1 cell lines. Given these results, we can think of proposing curcumin for anti-inflammatory and immunomodulatory use.
Continuation Newton methods with deflation techniques for global optimization problems
Authors: Luo Xin-long , Xiao Hang , Zhang Sen 
Published: January 2023

Abstract
The global minimum point of an optimization problem is of interest in engineering fields and it is difficult to be solved, especially for a nonconvex large-scale optimization problem. In this article, we consider a new memetic algorithm for this problem. That is to say, we use the continuation Newton method with the deflation technique to find multiple stationary points of the objective function and use those found stationary points as the initial seeds of the evolutionary algorithm, other than the random initial seeds of the known evolutionary algorithms. Meanwhile, in order to retain the usability of the derivative-free method and the fast convergence of the gradient-based method, we use the automatic differentiation technique to compute the gradient and replace the Hessian matrix with its finite difference approximation. Accordingto our numerical experiments, this new algorithm works well for unconstrained optimization problems and finds their global minima efficiently, in comparison to the other representative global optimization methods such as the multi-start methods (the built-in subroutine GlobalSearch.m of MATLAB R2021b, GLODS and VRBBO), the branch-and-bound method (Couenne, a state-of-the-art open-source solver for mixed integer nonlinear programming problems), and the derivative-free algorithms (CMA-ES and MCS).
Mathematics Subject Classification (2010) 65K05 · 65L05 · 65L20
Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis
Authors: Li Mingxuan , Yan Yu , Wang Chaonan , Tu Haixia 
Published: January 2023

Abstract
Background
Studies on the mortality of blunt abdominal aortic injury (BAAI) are rare, and the rates reported by them vary widely. We aimed to quantitatively analyze the data retrieved and reveal the hospital mortality of this disease more precisely.
Methods
Published studies were searched on Excerpta Medica Database (Embase), PubMed, Web of Science (WOS) and Cochrane Library without date restriction. We set the overall hospital mortality (OHM) and its 95% confidence interval (CI) of BAAI patients as the primary outcome measure. English references with data that met the selection criteria were included. The quality of all included studies was assessed by the Joanna Briggs Institute (JBI) checklist and the American Agency for Health Care Quality and Research’s (AHQR) cross-sectional study quality evaluation items. After data extraction, a meta-analysis was performed using the metaprop command of joint the Freeman-Tukey double arcsine transformation of data in Stata 16 software. Heterogeneity was assessed and reported as a percentage using the I² index value and as a P value using the Cochrane Q test. And various methods were used to find out the source of heterogeneity and analyze the sensitivity of the computation model.
Results
Of 2,147 references screened, 5 studies that involve 1,593 patients were included because of meeting the selection criteria. There were no low-quality references after assessment. There was 1 study that only included 16 juvenile BAAI patients was excluded from the meta-analysis of the primary outcome measure due to great heterogeneity. Because of low heterogeneity (I2 = 47.6%, P = 0.126 for Q test) after analysis using a random effects model, pooling the ESs of remaining four references using a fixed effects model yielded an OHM = 28.8% (95% CI, 26.5%-31.1%). The good stability of the model was verified by checking calculation. Egger’s test yielded P = 0.339, which shows the low publication bias of the model. In addition, we also performed meta-analyses and obtained the pooled hospital mortality of operation [13.5% (95%CI, 8.0%-20.0%)] and the pooled hospital mortality of non-operation [28.4% (95%CI, 25.9%-31.0%)] of BAAI, respectively.
Conclusions
BAAI has an OHM of 28.8%. This serious disease deserves more attention and research.
Sources of Growth in the Nigerian Economy From 1970 to 2018
Authors: Salisu Temitope Quadri 
Published: January 2023

Abstract
This study investigated the sources of growth in the Nigeria economy from 1970 to 2018 using neoclassical theory of economic growth also known as Solow growth model propounded by Robert Solow (1987). Different diagnostic tests were carried out which include descriptive statistics, correlation, and Ordinary Least Square (OLS). Descriptive statistics were used to examine if the explanatory variables and the dependent variable exhibit leptokurtosis characteristics. The OLS method was used to the models of sources of growth. The study adopted three dependent variables which are gross domestic product per capita (GDPPC), real gross domestic product (GDP) and growth of gross domestic product (GDP_GROWTH) in order to show which definition of growth is or are relevant to Nigeria. Using gross domestic product per capita as the dependent variable, the study found that two variables were statistically significant where both log of gross fixed capital formation and log of labour are statistically significant at 1%. The explanatory variables i.e. gross fixed capital formation and labour are positively related to the growth of gross domestic product in Nigeria therefore, a 1% increase in any of the explanatory variable will increase the growth of the economy by 3.180% and 1.094% respectively. Using real gross domestic product as the dependent variable, the study found that one variable is statistically significant where labour is statistically significant at 1%. The explanatory variables are positively related to the growth of gross domestic product in Nigeria. Therefore, a 1% increase in any of the explanatory variable will increase the growth of the economy by 0.409% and 1.731% respectively. In the same vein, using growth of gross domestic product as the dependent variable, the study found that the two variables are statistically significant where the log of gross fixed capital formation and labour are statistically significant at 1%. The explanatory variables that is gross fixed capital formation and labour are positively related to the growth of gross domestic product in Nigeria therefore, a 1% increase in any of the explanatory variable will increase the growth of the economy by about 1.194% and 1.139% respectively.