bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-training algorithm based on density peaks combining globally adaptive multi-local noise filter
Authors: Li Shuaijun , Lu Jia 
Published: April 2023

Self-training algorithm highlights the speed of training a supervised classifier through small labeled samples and large unlabeled samples. Despite its long considerable success, self-training algorithm has suffered from mislabeled samples. Local noise filters are designed to detect mislabeled samples. However, two major problem with this kind of application are: (a) Current local noise filters have not treated the spatial distribution of the nearest neighbors in different classes in much detail. (b) They are being disadvantaged when mislabeled samples are located in overlapping areas of different classes. Here, we develop an integrated architecture – self-training algorithm based on density peaks combining globally adaptive multi-local noise filter (STDP-GAMLNF), to improve detecting efficiency. Firstly, the spatial structure of the data set is revealed by density peak clustering, and it is used for empowering self-training to label unlabeled samples. In the meantime, after each epoch of labeling, GAMLNF can comprehensively judge whether a sample is a mislabeled sample from multiple classes or not, and it will reduce the influence of edge samples effectively. The corresponding experimental results conducted on eighteen UCI data sets demonstrate that GAMLNF is not sensitive to the value of the neighbor parameter k, and it is capable of adaptively finding the appropriate number of neighbors of each class.
Quantitative Sleep Electroencephalogram in Parkinson’s Disease: A Case-Control Study
Authors: Memon Adeel A. , Catiul Corina , Irwin Zachary , Pilkington Jennifer , Memon Raima A. , Joop Allen , Wood Kimberly H. , Cutter Gary , Miocinovic Svjetlana , Amara Amy W. 
Published: April 2023

Background: Sleep disorders are common in Parkinson’s disease (PD) and include alterations in sleep-related EEG oscillations. Objective: This case-control study tested the hypothesis that patients with PD would have a lower density of Scalp-Slow Wave (SW) oscillations and higher slow-to-fast frequencies ratio in rapid eye movement (REM) sleep than non-PD controls. Other sleep-related quantitative EEG (qEEG) features were also examined, including SW morphology, sleep spindles, and Scalp-SW spindle phase-amplitude coupling. Methods: Polysomnography (PSG)-derived sleep EEG was compared between PD participants ( n = 56) and non-PD controls ( n = 30). Following artifact rejection, sleep qEEG analysis was performed in frontal and central leads. Measures included SW density and morphological features of SW and sleep spindles, SW-spindle phase-amplitude coupling, and spectral power analysis in Non-REM (NREM) and REM. Differences in qEEG features between PD and non-PD controls were compared using two-tailed Welch’s t-tests, and correction for multiple comparisons was performed per the Benjamini-Hochberg method. Results: SW density was lower in PD than in non-PD controls (F = 13.5, p’ = 0.003). The PD group also exhibited higher ratio of slow REM EEG frequencies (F = 4.23, p’ = 0.013), higher slow spindle peak frequency (F = 24.7, p’ < 0.002), and greater SW-spindle coupling angle distribution non-uniformity (strength) (F = 7.30, p’ = 0.034). Conclusion: This study comprehensively evaluates sleep qEEG including SW-spindle phase amplitude coupling in PD compared to non-PD controls. These findings provide novel insights into how neurodegenerative disease disrupts electrophysiological sleep rhythms. Considering the role of sleep oscillatory activity on neural plasticity, future studies should investigate the influence of these qEEG markers on cognition in PD.
Impacto de la pandemia por SARS-CoV-2 en los pacientes que acuden a urgencias de pediatría por problemas de salud mental
Authors: Merino-Hernández Amaia , Jové-Blanco Ana , Palacios-Bermejo Andrea , Rodríguez-Represa Javier , Ferrero García-Loygorri Clara , Vázquez-López Paula 
Published: April 2023

El confinamiento instaurado durante la pandemia por SARS-CoV-2 y el efecto del virus en la población podrían suponer un factor precipitante para trastornos de salud mental en la población infantil. Objetivo: Comparar los motivos de consulta, diagnósticos al alta, tasa de ingreso y reconsulta de pacientes pediátricos que acuden al Servicio de Urgencias por trastornos de salud mental antes y después del confinamiento por SARS-CoV-2. Pacientes y Método: Estudio descriptivo, retrospectivo. Se incluyeron pacientes menores de 16 años con motivos de consulta relacionados con salud mental durante los periodos preconfinamiento (01/07/2018-01/07/2019) y postconfinamiento (01/07/2020- 01/07/2021). Se comparó la frecuencia de diagnósticos de salud mental, necesidad de inicio de fármacos, de hospitalización y de reconsultas. Resultados: Se incluyeron 760 pacientes (399 preconfinamiento y 361 postconfinamiento). Tras el confinamiento se observó un aumento del 45,7% en la frecuencia de consultas relacionadas con salud mental respecto al total de consultas de urgencias. La alteración del comportamiento fue el motivo de consulta más frecuente en ambos grupos (34,3% vs. 36,6%, p = 0,54). En el periodo postconfinamiento aumentaron significativamente las consultas relacionadas con intentos autolíticos (16,3% vs. 24,4%, p < 0,01) y el diagnóstico de depresión (7,5% vs. 18,5%, p < 0,01). Se objetivó un aumento del 58,8% en los pacientes que ingresaron respecto al total de pacientes que acudieron a urgencias (0,17% vs. 0,27%, p = 0,003) y un aumento del número de reconsultas (12% vs. 17,8%, p = 0,026). No se observaron diferencias en los días de hospitalización (7 días [RIC 4-13] vs. 9 días [RIC9-14], p0,45). Conclusión: En el periodo postconfinamiento se incrementó la proporción de pacientes pediátricos que acudieron a urgencias con alteraciones de la salud mental.
URGENSI DESKRIPSI PEKERJAAN DALAM MENINGKATKAN KINERJA KARYAWAN : SEBUAH STUDI LITERATUR
Authors: Astuti Nidya , Ikhwan Khairul 
Published: April 2023

Penelitian ini memiliki tujuan yaitu untuk mengetahui dampak dari deskripsi pekerjaan bagi karyawan. Sampel penelitian ini adalah artikel yang dipublikasikan pada 16 jurnal nasional berakreditasi pada tahun 2016 sampai dengan tahun 2021. Sampel diperoleh sebanyak 17 artikel yang membahas mengenai deskripsi pekerjaan. Metode yang digunakan yaitu metode charting the field yang dikembangkan oleh (Hesford et al., 2007). Penelitian ini mengklasifikasikan artikel berdasarkan topik, metode penelitian, dan sektor penelitian. Topik yang paling banyak diteliti dari variabel dependen adalah variabel kinerja karyawan, variabel independen yang paling banyak diteliti adalah variabel deskripsi pekerjaan. Metode penelitian yang paling banyak digunakan adalah metode kuantitatif dan sebagian besar penelitian dilakukan pada sektor swasta.
Affix rivalry in French demonym formation: The role of linguistic and non-linguistic parameters
Authors: Thuilier Juliette , Tribout Delphine , Wauquier Marine 
Published: April 2023

Affix rivalry is defined as the phenomenon of morphological competition where affixes and meaning are in a many-to-one relationship. Because of their poor semantic content, demonyms are perfect candidates for the investigation of selectional constraints in such a context. Indeed the morphological processes they originate from are characterized by their shared, straightfoward semantic relation, as they denote inhabitants linked to the toponym they derive from, which allows for the apparently simplified scrutinization of non-semantic properties. Investigations suggest a more nuanced and complex reality.The present study provides a quantitative and statistical investigation of the rivalry between French - ois, - ais, - ien and - éen suffixes. It notably relies on phonological and morphological features. Its contribution pertains to the use of statistical modeling to provide a quantitative description and to the integration of extralinguistic features on the nature of geographical proximity in a quantitative approach. The study shows that while the model cannot accurately predict the suffix of a given demonym based on these features, it still draws on the main tendencies underlying affix rivalry in the formation of French demonyms.
Comparative transcriptome analysis of Peromyscus leucopus and C3H mice infected with the Lyme disease pathogen
Authors: Gaber Alhussien M. , Mandric Igor , Nitirahardjo Caroline , Piontkivska Helen , Hillhouse Andrew E. , Threadgill David W. , Zelikovsky Alex , Rogovskyy Artem S. 
Published: April 2023

Lyme disease (LD), the most prevalent tick-borne disease of humans in the Northern Hemisphere, is caused by the spirochetal bacterium of Borreliella burgdorferi (Bb) sensu lato complex. In nature, Bb spirochetes are continuously transmitted between Ixodes ticks and mammalian or avian reservoir hosts. Peromyscus leucopus mice are considered the primary mammalian reservoir of Bb in the United States. Earlier studies demonstrated that experimentally infected P. leucopus mice do not develop disease. In contrast, C3H mice, a widely used laboratory strain of Mus musculus in the LD field, develop severe Lyme arthritis. To date, the exact tolerance mechanism of P. leucopus mice to Bb-induced infection remains unknown. To address this knowledge gap, the present study has compared spleen transcriptomes of P. leucopus and C3H/HeJ mice infected with Bb strain 297 with those of their respective uninfected controls. Overall, the data showed that the spleen transcriptome of Bb-infected P. leucopus mice was much more quiescent compared to that of the infected C3H mice. To date, the current investigation is one of the few that have examined the transcriptome response of natural reservoir hosts to Borreliella infection. Although the experimental design of this study significantly differed from those of two previous investigations, the collective results of the current and published studies have consistently demonstrated very limited transcriptomic responses of different reservoir hosts to the persistent infection of LD pathogens.ImportanceThe bacterium Borreliella burgdorferi (Bb) causes Lyme disease, which is one of the emerging and highly debilitating human diseases in countries of the Northern Hemisphere. In nature, Bb spirochetes are maintained between hard ticks of Ixodes spp. and mammals or birds. In the United States, the white-footed mouse, Peromyscus leucopus, is one of the main Bb reservoirs. In contrast to humans and laboratory mice (e.g., C3H mice), white-footed mice rarely develop clinical signs (disease) despite being (persistently) infected with Bb. How the white-footed mouse tolerates Bb infection is the question that the present study has attempted to address. Comparisons of genetic responses between Bb-infected and uninfected mice demonstrated that, during a long-term Bb infection, C3H mice reacted much stronger, whereas P. leucopus mice were relatively unresponsive.
An erosive neritic area of Shantou in coastal NE South China Sea since at least MIS 5 revealed by OSL dating of cores
Authors: Zhong Jiemei , Liu Bohui , Ou Yang , Tian Ruonan , Shan Jingxiang , Xu Yantian , Wang Feng , Abbas Mahmoud , Zhang Ke , Lai Zhongping 
Published: April 2023

The neritic region of the Chaoshan plain is located on the northeastern (NE) boundary of the South China Sea (SCS). Despite the extensive research on the stratigraphic architecture and sedimentary processes within the Chaoshan plain, the neighboring neritic area remains largely unexplored. In this study, we provide a new set of ages on seventeen quartz optically stimulated luminescence (OSL) dating results from four cores (SY2-2, SY3-1, SY3-2, and HS02) to investigate the regional chronostratigraphy and sedimentology of the area. The samples were collected at depths ranging from 0.6 to 73.5 m and yielded ages ranging from 4.9 ± 0.3 ka to &gt;139 ± 28 ka. Sedimentation thickness from cores SY3-2, SY2-2, and HS02 is less than 4.2 m, 5.5 m, and 6.4 m, respectively, since at least Marine Isotope Stage (MIS) 5, and the Holocene sediments of core SY3-2 are less than 4.2 m thick. The preservation state of the sediments in the area is poor since at least 83.6 ka, indicating an intensified erosion in the neritic region of the northeastern South China Sea (NESCS) since at least MIS 5. This erosion may have been caused by fluvial incision resulting from sea-level decline during the last glacial period, as well as strong transportation caused by coastal currents.
Association of weight range with telomere length: A retrospective cohort study
Authors: Wang Xinyu , Wen Jingli , Qu Qiang , Gu Shujun , Zhang Lixi , Li Yu , Qi Xu 
Published: April 2023

ObjectivePrevious research has shown a significant association between weight and telomere length, but did not take into consideration weight range. The study was to investigate the association of weight range with telomere length.MethodsData of 2918 eligible participants aged 25-84 years from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 cycle were analyzed. Information about demographic variables, lifestyle factors, anthropometric variables, and medical comorbidities were included. Univariate and multivariate linear regression model with adjustments for potential confounders were employed to determine the association between weight range and telomere length. A non-parametrically restricted cubic spline model was used to illustrate the possible non-linear relationship.ResultsIn univariate linear regression, BMImax, BMI range, and weight range all revealed significant negative associations with telomere length. However, annual rate of BMI/weight range showed a significant positive associations with telomere length. There was no significant association between telomere length and BMImin. After adjusting for potential confounders, the inverse associations persisted in BMImax (β=-0.003, P&lt;0.001), BMI range (β=-0.002, P=0.003), and weight range (β=-0.001, P=0.001). Furthermore, annual rate of BMI range (β=-0.026, P=0.009) and weight range (β=-0.010, P=0.007) presented negative associations with telomere length, after adjusting for covariates in Model 2-4. The association between BMImin (β =-0.002, P=0.237) and telomere length still could not reach statistical significance in multivariate linear regression model. The results of restricted cubic spline analysis showed that BMImax (P for nonlinear =0.026), BMI range (P for nonlinear =0.022), weight range (P for nonlinear =0.035), annual rate of BMI range (P for nonlinear =0.030), and annual rate of weight range (P for nonlinear =0.027) all had nonlinear inverse associations with telomere length.ConclusionsThe study suggests that weight range is inversely associated with telomere length in U.S. adults. Larger weight fluctuation may accelerate telomere shortening and aging.
Salivary cortisol, dehydroepiandrosterone, and chromogranin A levels in patients with gingivitis and periodontitis and a novel biomarker for psychological stress
Authors: Lee Yeon-Hee , Suk Chon , Shin Seung-Il , Hong Ji-Youn 
Published: April 2023

IntroductionThis study aimed to investigate the neuroendocrine responses based on cortisol, dehydroepiandrosterone (DHEA), cortisol/DHEA ratio, and chromogranin A levels, which reflect the activity of the hypothalamic-pituitary-adrenal axis, according to the presence or absence of psychological stress in patients with gingivitis and periodontitis compared to that in healthy controls.MethodsIn total, 117 patients (60 women, mean age: 36.29 ± 19.03 years) participated in this case-control study, comprising 32 healthy controls, 49 patients with gingivitis, and 36 patients with periodontitis. We investigated the presence of psychological stress and salivary characteristics, and analyzed the stress-related biomarkers of cortisol, DHEA, cortisol/DHEA ratio, and chromogranin A in the stimulated saliva.ResultsSalivary cortisol and chromogranin A levels increased with the severity of periodontal disease; their levels were the highest in the periodontitis group and were significantly higher in the following descending order: periodontitis, gingivitis, and healthy control groups (all values of p &lt; 0.001). Additionally, the DHEA levels and cortisol/DHEA ratio were higher in the periodontitis group than those in the healthy control group (all values of p &lt; 0.001). A multivariate logistic regression analysis revealed that the factors predicting above-average cortisol levels were periodontitis (odds ratio [OR] = 256.829; p &lt; 0.001), women (OR = 6.365; p = 0.004), and psychological stress (OR = 6.036; p = 0.007); those predicting above-average cortisol/DHEA ratios were periodontitis (OR = 11.436; p &lt; 0.001), psychological stress (OR = 3.977; p = 0.003), and women (OR = 2.890; p = 0.026). Thus, periodontitis and psychological stress were significant and strong predictors of above-average cortisol levels and cortisol/DHEA ratios. In the gingivitis group, salivary cortisol levels (r = 0.381, p = 0.007) and cortisol/DHEA ratios (r = 0.479, p &lt; 0.001) were correlated with the presence of psychological stress. In the periodontitis group, increased cortisol/DHEA ratios (r = 0.412, p = 0.013) and lowered salivary buffer capacities (r = -0.334, p = 0.047) were correlated with the presence of psychological stress.ConclusionPeriodontitis is a multifactorial disease resulting in inflammatory tissue destruction, which differs from gingivitis and a healthy state. Differences in stress-related neuroendocrine markers were revealed based on the severity of periodontal disease. The biomarkers that could be classified according to disease severity were salivary cortisol and chromogranin A levels. Above-average cortisol levels and cortisol/DHEA ratios are significant predictors of psychological stress in patients with gingivitis and periodontitis.
Deviation between willingness and actual behavior regarding community participation in protected areas: A case study in Shengjin lake national nature reserve in China
Authors: Wu Tianyu , Jia Weiguo , Wang Qianwen 
Published: April 2023

Introduction: The deviation between high willingness and poor actual behaviors in community participation has become an obstacle to achieving effective management and resource protection of protected areas. Therefore, it is necessary to investigate this deviation and its influencing factors.Methods: Based on a field survey of community residents in the Shengjin Lake National Nature Reserve (SJLNNR) in Anhui Province, China, this study uses a Logistic-ISM model to analyze the key factors influencing the deviation and the hierarchical structure supporting those key factors.Results: There is a significant deviation between participation willingness and actual behavior in SJLNNR. This deviation is characterized by eight key factors. Among these, awareness of the necessity of establishing SJLNNR is a direct factor at the surface level. Participation of important or recognizable people; average annual family income; understanding of environmental protection laws and regulations; realization of environmental improvement effect; satisfaction with SJLNNR authority; and future earnings expectations are all intermediate indirect factors. Furthermore, resident member is a fundamental factor. Resident members refer to those who live at home for six months or more during a calendar year.Discussion: These results indicate that there are three possible practical reasons for the deviation: 1) The lack of young and middle-aged adults is the root cause. 2) Inadequate ecological compensation is the direct trigger. 3) Individual internal psychological factors have significant effects. Furthermore, this study provides policy implications for converting willingness into actual participation in the community and promoting sustainable development.
Sepsis survivors and caregivers perspectives on post–acute rehabilitation and aftercare in the first year after sepsis in Germany
Authors: Born Sebastian , Matthäus-Krämer Claudia , Bichmann Anna , Boltz Hannah-Sophia , Esch Marlene , Heydt Luisa , Sell Stefan , Streich Kathleen , Scherag André , Reinhart Konrad , Hartog Christiane S. , Fleischmann-Struzek Carolin 
Published: April 2023

BackgroundSepsis survivors often suffer from new morbidities. Current rehabilitation therapies are not tailored to their specific needs. The perspective of sepsis survivors and their caregivers on rehabilitation and aftercare is insufficiently understood. We aimed to assess how sepsis survivors in Germany rated the suitability, extent and satisfaction with rehabilitation therapies that they underwent in the year following the acute sepsis episode.MethodsProspective mixed-methods, multicenter study among a cohort of adult ICU-treated sepsis survivors and their caregivers. Interviews were conducted 6 and 12 months after ICU discharge by telephone and comprised closed as well as open-ended questions. Primary outcomes were the utilization and patient satisfaction with inpatient and outpatient rehabilitation and post-sepsis aftercare in general. Open-ended questions were analyzed according to the principles of content analysis.ResultsFoun hundred interviews were performed with 287 patients and/or relatives. At 6 months after sepsis, 85.0% of survivors had applied for and 70.0% had undergone rehabilitation. Among these, 97% received physical therapy, but only a minority reported therapies for specific ailments including pain, weaning from mechanical ventilation, cognitive deficits of fatigue. Survivors were moderately satisfied with the suitability, extent, and overall results of received therapies and perceived deficits in the timeliness, accessibility, and specificity of therapies as well as deficits in the structural support frameworks and patient education.ConclusionFrom the perspective of survivors who undergo rehabilitation, therapies should already begin in hospital, be more appropriate for their specific ailments and include better patient and caregiver education. The general aftercare and structural support framework should be improved.
Risk factors of incontinence-associated dermatitis among critically ill patients: A systematic review and meta-analysis
Authors: Jiang Hongzhan , Shen Jiali , Lin Huihui , Xu Qiuqin , Li Yuanchan , Chen Lijuan 
Published: April 2023

ObjectivesIncontinence-associated dermatitis (IAD) is increasingly found among critically ill patients, but the risk factors for IAD in these patients are currently unclear. The purpose of this meta-analysis was to identify the risk factors of IAD in critically ill patients.MethodsWeb of Science, PubMed, EMBASE, and Cochrane Library were systemically searched until July 2022. The studies were selected based on inclusion criteria, and data were independently extracted by two researchers. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. Odds ratios (ORs) and their associated 95% confidence intervals (CIs) were used to identify significant differences in the risk factors. The I2 test was used to estimate the heterogeneity of studies, and Egger's test was used to assess the potential publication bias.ResultsA total of 7 studies enrolling 1,238 recipients were included in the meta-analysis. Age ≥ 60 (OR = 2.18, 95% CI: 1.38~3.42), female sex (OR = 1.76, 95% CI: 1.32~2.34), dialysis (OR = 2.67, 95% CI: 1.51~4.73), fever (OR = 1.55, 95% CI: 1.03~2.33), vasoactive agent (OR = 2.35, 95% CI: 1.45~3.80), PAT score ≥ 7 (OR = 5.23, 95% CI: 3.15~8.99), frequency of bowel movement &gt; 3times/d (OR = 5.33, 95% CI: 3.19~8.93), and liquid stool (OR = 2.61, 95% CI: 1.56~4.38) were the risk factors of IAD among critically ill patients.ConclusionsMany risk factors are related to IAD among critically ill patients. Nursing staff should pay more attention to evaluating the risk of IAD and enhance the care of high-risk groups.