bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis Of Acceptance And Profits Of The Tempe Household Industry
Authors: Adil Nindianata Sekar , Sumartono Eko , Yumiati Yossie 
Published: January 2025

Purpose : The aim of this research is to determine the advantages and acceptance obtained by each owner of home-based tempeh industries located in Sukaraja District. Method: The research conducted in Sukaraja District used a sampling method that took certain considerations into account, namely the duration of the business (10 years) and the production volume (500 kg per month). After consideration, the number of respondents obtained was 5 (five) respondents. Quantitative research, the data obtained in the field is processed using Microsoft Excel. Results: This study presents the revenue of home-based tempeh industries in Sukaraja District for the month of April, with an average revenue of Rp.23,325,000. Poernomo's tempeh industry generated a revenue of Rp.29,935,000, Randat earned Rp.24,450,000, Salim Rp.22,960,000, Saumi Rp.21,480,000, and Agil's industry earned Rp.17,800,000. The profits obtained from the five home-based tempeh industries are as follows: Poernomo's Rp.11,890,698, Randat's Rp.7,371,032, Salim's Rp.7,806,869, Saumi's Rp.6,085,774, Agil's Rp.4,295,209, with an average profit of Rp.7,489,916. Findings: Success acceptance highest can be attributed to several key factors, including operational efficiency and greater economies of scale and greater economies of scale Novelty: This study provides new insights into the profits earned by tempeh artisans in Sukaraja sub-district. Sukaraja sub-district. Originality: This study offers an analysis of the profitability of the household-scale profit analysis of the household-scale tempeh industry in Sukaraja District. Conclusion: It can be seen that the income and profits obtained by the owners of this home-based tempe industry are very beneficial for them. Type of paper : Empirical Research Article
The Role Of Taruna Tani In Supporting Organic Agriculture (Case Study Of Gentungan Village, Mojogedang District, Karanganyar Regency)
Authors: Oktaviana Anisya , Setyowati Retno , Rusdiyana Eksa 
Published: January 2025

Purpose: This study aims to analyze the roles, efforts, supporting factors, and obstacles of the youth farmer group (taruna tani) in supporting organic farming in Gentungan Village, Mojogedang District, Karanganyar Regency. Methodology: The research employed a qualitative descriptive method with purposive sampling for location selection. Informants were determined using purposive and snowball techniques, involving 15 individuals. Data were collected through observation, in-depth interviews, and documentation, and analyzed using Miles and Huberman’s approach. Results: The youth farmer group plays roles as family members, community members, and contributors to agricultural development. Findings: Efforts include fostering entrepreneurship through the production and sale of organic fertilizers and rice, and agribusiness skill training facilitated by stakeholders. Originality and Novelty: The youth farmer group demonstrates a significant role in advancing organic farming in the village. Conclusion: Supporting factors include self-awareness, organizational structure, government and mentor support, and shared interests. Obstacles include peer influence and members’ main job commitments. Type of Paper: Empirical research article.
Youtube As An Agricultural Extension Media
Authors: Mujiono Mujiono , Dianthi Martha Heriniazwi 
Published: January 2025

Purpose: This study aims to analyze the meaning of signs in a YouTube video by Penyuluh Pertanian Lapangan titled Pupuk Organik Cair ini 100 Kali Lebih Kuat Dari Air Cucian Beras/Leri - JAKABA SUPER with a duration of 13 minutes and 45 seconds, viewed 2,966,730 times. Methodology: The research adopts a qualitative approach using John Fiske’s semiotics analysis. Results: The video highlights the role of agricultural extension workers as a “bridge” between government policies and farmers. Technical information is conveyed in simple language, supported by clear visuals for better understanding. Findings: The content empowers farmers through relevant, practical education. Structured narration and clean video editing enhance communication effectiveness. Originality: This study emphasizes a semiotic approach in digital agricultural content. Novelty: It provides in-depth analysis of YouTube as an educational medium in agriculture. Conclusion: The video integrates technical education, ecological ideology, and modern technology to promote sustainable farming practices. Type of Paper: Qualitative research paper.
Resilience first aid: Primary prevention through a strength-based peer support programme
Authors: Rossouw Jurie G. , Ruberto Maria 
Published: January 2025

Orientation: Peer support and resilience are crucial for mental health, particularly in high-stress occupations such as healthcare and emergency services. Existing interventions primarily focus on reactive measures, leaving a gap in proactive mental health strategies.Research purpose: This study aimed to investigate the effectiveness of the Resilience First Aid (RFA) programme, incorporating the Predictive 6 Factor Resilience (PR6) model and the ALL Protocol, in enhancing resilience and peer support.Motivation for the study: There is a pressing need for primary prevention strategies to address the growing mental health challenges in high-stress professions. These challenges include burnout, post-traumatic stress disorder (PTSD), and suicide, among others. This study addresses the knowledge gap by exploring a strength-based, proactive approach to peer support.Research approach/design and method: A literature review was conducted to examine gaps in peer support and explore the theoretical framework of RFA. The study draws on neurobiological insights and integrates psychotherapeutic principles to develop a resilience-focused intervention.Main findings: Resilience First Aid training significantly improved participants’ personal resilience, peer support skills and ability to recognise suicide risk factors. The ALL Protocol facilitated emotional regulation and constructive problem-solving in peer support interactions, aligning with neuroscience-based insights.Implications for practice: Implementing RFA in high-stress environments could enhance workforce resilience and reduce the prevalence of acute mental health crises. The programme’s structured, proactive approach addresses current gaps in mental health support systems.Contribution/value-add: This study contributes by presenting a comprehensive, proactive model for peer support and resilience, offering a structured conversational tool (ALL Protocol) that can be applied across various professional settings.
Consumption of folk medicine in men-seeking treatment for infertility
Authors: Baazeem Abdulaziz , Alqurashi Thamer Mishal M. , Alharbi Yasser Homaidi H. , Aldahhas Raad Abdullah D. , Fatani Mutaz Hassan A. 
Published: January 2025

Background:
Male infertility is a major health problem that can have a tremendous negative impact on the affected individuals and couples. The use of folk medicine is common practice in the Middle Eastern region, especially before seeking conventional medical treatment. Unfortunately, some of these remedies might be potentially harmful. This study aims to assess the use of folk medicine before formal medical evaluation by a male infertility specialist among men in couples with subfertility in Saudi Arabia.

Materials and Methods:
A retrospective study of prospectively documented data was conducted among male patients who presented for evaluation of their infertility at one center in Jeddah, Saudi Arabia, from May 1, 2020, to April 30, 2021, to assess the prevalence of the use of traditional medicine among these patients.

Results:
The total number of patients who visited the center for infertility assessment during the specified period was of 427. Most patients had primary infertility (64.4%). Table 1 summarizes the demographic data of the patient population. About 55.3% of the patients were 40 years old or less. Patients who consumed some form of alternative medicine are 38.9%. A clinical varicocele was detected in 57.8% of these men. Patients who use alternative medicine had significantly lower semen concentration and estradiol levels (P = 0.02 similarly).

Conclusion:
About 38.9% of patients who attended our clinic were using some alternative medicine. Furthermore, patients who use alternative medicine had significantly less sperm motility and progressive motility.
Gender bias in urology: The role of gender in selecting urology as a medical specialty
Authors: Alnazari Mansour , Aljohani Abdullah K. , Rajih Emad S. , Bakhsh Abdulaziz , Alghamdi Ghadi S. , Sebaa Faris S. , Alraddadi Ali A. , Moalwi Adel 
Published: January 2025

Background:
Gender inequality has been prevalent in the history of medicine, specifically within surgical specialties. Although there have been advances, urology has remained overwhelmingly male-dominant, with slow growth in female recruitment.

Objectives:
The study aimed to assess whether the gender influences selection of medical specialty, especially gender bias in urology.

Materials and Methods:
A cross-sectional study was conducted among undergraduate medical students in Saudi Arabian medical schools to explore the influence of gender on urology specialty selection. Data were collected from November 2023 to June 2024 using a structured questionnaire administered electronically. A pilot study was conducted to evaluate the questionnaire’s reliability and clarity. Data were analyzed using descriptive and inferential statistics. The questionnaire demonstrated acceptable reliability.

Results:
The total study participants were 602 medical students. The dataset reveals a balanced gender representation, with males constituting 55.6% and females 44.4%. A substantial majority, 94.5%, expressed a definitive willingness to pursue further residency training following graduation, indicating a robust commitment to advancing their medical careers. However, while evaluating interest in urology, the statistics revealed a potential disparity, with only 43.2% affirmatively considering urology as a specialty, contrasted against 56.8% who would not. The study shows that the participants’ considering urology as a specialty has a statistically significant relation to gender (P = 0.0001) as 72.3% of those who would consider the specialty were males compared to only 27.7% for females. The data also show a concerning trend where 21.8% of those uninterested in urology reported insufficient exposure during medical school as a deterrent, while others found the specialty to be embarrassing or simply uninteresting, accounting for 70.8% of the negative responses.

Conclusion:
This study reveals a significant gender disparity in urology specialty selection among medical students. While the majority of students intend to pursue residency training, male students are significantly more likely to consider urology as a specialty compared to female students. Factors such as limited exposure and negative perceptions contribute to the underrepresentation of women in urology. Addressing these issues is crucial to achieving gender equality within the field.
Identifying adipocyte-derived exosomal miRNAs as potential novel prognostic markers for radiotherapy of esophageal squamous cell carcinoma
Authors: Ge Yang-Yang , Xia Xiao-Chun , Wu An-Qing , Ma Chen-Ying , Yu Ling-Hui , Zhou Ju-Ying 
Published: January 2025

BACKGROUND
Radiation resistance limits radiotherapy efficacy in esophageal squamous cell carcinoma (ESCC). The tumor microenvironment, particularly adipocytes, plays a role in promoting cancer progression. Extracellular vesicles and microRNAs (miRNAs) regulate gene expression and hold prognostic potential for esophageal carcinoma. Elucidating radioresistance mechanisms and identifying radiosensitization targets can help enhance radiotherapy efficacy for esophageal cancer.
AIM
To investigate the potential role of miRNAs derived from adipocyte exosomes as prognostic markers for radiotherapy efficacy in ESCC.
METHODS
Free adipocytes were isolated from human thoracic adipose tissue. A co-culture model of adipocytes and ESCC cells was established to observe colony formation and cell survival post-irradiation. ESCC cell apoptosis was assessed by flow cytometry. Western Blot and immunofluorescence assays were performed to evaluate DNA damage in ESCC cells post-irradiation. Adipocyte-derived exosomes were isolated by ultracentrifugation and identified by electron microscopy. A similar set of experiments was performed on ESCC cells to analyze cell survival, apoptosis, and DNA damage post-radiation exposure. Exosomes from adipose tissue and serum exosomes from ESCC patients pre- and post-radiotherapy were subjected to high-throughput miRNA-sequencing and validated using real-time quantitative polymerase chain reaction. The correlation between potential target miRNAs and the short-term prognosis of radiotherapy in ESCC was evaluated by receiver operating characteristic curve analysis.
RESULTS
Co-culturing adipocytes with ESCC cells enhanced radioresistance, as evidenced by increased colony formation. Adipocyte co-culture reduced ESCC cell apoptosis and DNA damage post-radiation. Adipocyte-derived exosomes similarly conferred radioresistance in ESCC cells, decreasing apoptosis and DNA damage post-irradiation. High-throughput miRNA-sequencing identified miR-660-5p in serum and adipose tissue exosomes. Patients with high expression of serum exosome miR-660-5p showed poor prognosis after radiotherapy.
CONCLUSION
Adipocyte-derived exosomal miR-660-5p is a potential biomarker for evaluating radiotherapy efficacy in ESCC.
Efficacy of sorafenib combined with transarterial chemoembolization in the treatment of advanced hepatocellular carcinoma: A meta-analysis
Authors: Xu Mei , Zhou Si-Rui , Li Ya-Ling , Zhang Chen-Hao , Liao Da-Zhong , Wang Xiao-Li 
Published: January 2025

BACKGROUND
The combination of sorafenib with transarterial chemoembolization (TACE) is being investigated for its potential to improve outcomes in advanced hepatocellular carcinoma (HCC).
AIM
To evaluate the efficacy of this combined treatment strategy in enhancing overall survival (OS) and progression-free survival (PFS) compared to monotherapies.
METHODS
A systematic review was conducted following the PRISMA guidelines. A comprehensive search was performed across PubMed, EMBASE, Web of Science, and the Cochrane Library up to May 8, 2024. Studies were included if they compared sorafenib plus TACE to sorafenib alone or TACE alone in adults with advanced HCC. Primary outcomes were OS, PFS, response rates, and safety profiles. Data extraction and quality assessment were independently performed by two reviewers. Heterogeneity was assessed using the I² statistic, and a random-effects model was applied for pooling data. Sensitivity analysis and publication bias assessment were also conducted.
RESULTS
A total of twelve studies involving 1174 patients met the inclusion criteria. Significant heterogeneity was observed for both OS (I² = 72.6%, P < 0.001) and PFS (I² = 83.7%, P < 0.001). The combined treatment of sorafenib with TACE significantly improved OS [hazard ratio (HR) = 0.60, 95% confidence interval (CI): 0.44-0.76] and PFS (HR = 0.54, 95%CI: 0.38-0.69). Sensitivity analysis confirmed the robustness of these findings. Funnel plots and Egger's test indicated no significant publication bias.
CONCLUSION
Sorafenib combined with TACE significantly enhances both OS and PFS in patients with advanced HCC compared to monotherapy. This combination therapy represents a promising approach to improving clinical outcomes in advanced liver cancer.
Malignant perivascular epithelioid cell tumor of the colorectum: Clinicopathological characterization, diagnosis and treatment process of 7 cases
Authors: Ma Ming-Fei , Chi Zhen-Yu , Zhao Li-Juan , Zhai Wei , Zhong Wen , Wang Song 
Published: January 2025

BACKGROUND
Perivascular epithelioid cell tumor (PEComa) of the colorectum is exceedingly rare, with only a few published reports. It presents with a wide spectrum of biological behavior, ranging from benign to malignant. The prognosis for malignant PEComa is poor and there is little consensus on its treatment.
AIM
To fully characterize PEComa and standardize its diagnosis and treatment.
METHODS
Patients with colorectal malignant PEComa were identified from the First Affiliated Hospital, Zhejiang University School of Medicine and People's Hospital of Anji. Cases with controversial pathology and cases lost to follow-up were excluded, leaving seven remaining cases that formed the basis of the study. We collected relevant clinicopathological, therapeutic and followup details. Disease stage and progression were assessed by contrast-enhanced computed tomography at baseline and at 3-month intervals.
RESULTS
The mean age was 43 years, with a range of 5 years to 73 years. The average body mass index was 21.8 ± 3.0 kg/m2, and 71.4% of cases occurred in the colon. The main symptoms of colorectal PEComas were abdominal mass and hematochezia. The most common microscopic finding of malignant behavior was infiltrative growth. Immunohistochemical analysis found that 6/7 cases were positive for HMB45, 5/7 were positive for melan-A, and 3/5 were positive for MiTF. The watch-and-wait approach to treatment was a risky option. Radical resection was preferable to systemic treatment. The median progression-free survival exceeded 38 months, longer than previously reported.
CONCLUSION
Radical or extended resection is the key to prolonged survival of malignant PEComa. More meaningful studies are urgently needed to establish the standardized diagnosis and treatment.
THE CONTRIBUTION OF EUROPOL, FRONTEX, EPPO AND EUROJUST IN THE AREA OF FREEDOM, SECURITY AND JUSTICE
Authors: Korontzis Tryfon 
Published: January 2025

The aim of this paper is the critical presentation of the European Union (EU) legal texts and especially of the main European Organizations that are activated in the Area of Freedom, Security and Justice (AFSJ) [Schengen Area] and specifically in dealing with organized crime and terrorism in the EU [Europol, Eurojust, Frontex as well as the recent institution of the European Public Prosecutor Office (EPPO)] and in particular the powers and duties assigned to them and the efficiency related to their action in the area in question. Research has been carried out in the areas of freedom, security and justice: general aspects, asylum policy, immigration policy, management of external borders, judicial cooperation in criminal cases, and police cooperation at the EU level by evaluating EU legal texts, scientific articles and literature and drawing on data from the EU specific Agencies.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0774/a.php" alt="Hit counter" /></p>
BUILDING A CHINA - AFRICA COMMUNITY WITH A SHARED FUTURE: PATHWAYS AND PRACTICE
Authors: Kitili Ike M. 
Published: January 2025

Building a China-Africa Community with a Shared Future requires a nuanced understanding of its concept and the broader vision of a Community with a Shared Future for Mankind. By tracing historical and contemporary drivers, this exploration identifies five strategic pathways: fostering cultural exchange, promoting inclusive economic growth, strengthening collaboration in poverty reduction and public health, establishing a Peace and Security Forum, and advancing climate-focused environmental initiatives. Successfully navigating international complexities and Africa’s internal diversity demands enhanced dialogue and respect for African development autonomy. This endeavour holds transformative potential, rooted in political trust, economic partnership, and shared prosperity, to address global challenges.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0447/a.php" alt="Hit counter" /></p>
Comparison of the Laws Governing Online Loans in England and Indonesia
Authors: Nurhilmiyah  , Purba Hasim , Sitompul Zulkarnain , Azwar Tengku Keizerina Devi 
Published: January 2025

Introduction: This study compares the laws governing online lending, or peer-to-peer lending, in the UK and Indonesia, two nations with distinct fintech market features. This paper examines the legal framework that oversees the online lending sector in both nations using a normative juridical and comparative approach, with a particular emphasis on consumer protection, risk management, and regulatory supervision.

Objective: According to the study's findings, Indonesia's fintech industry is governed by the Financial Services Authority, but the UK has more developed laws with the Financial Conduct Authority (FCA) as the only body in charge. in contrast to Indonesia, the UK has more stringent licensing procedures and higher minimum capital requirements.

Theoretical Framework: According to the study's findings, Indonesia's fintech industry is governed by the Financial Services Authority, but the UK has more developed laws with the Financial Conduct Authority (FCA) as the only body in charge. in contrast to Indonesia, the UK has more stringent licensing procedures and higher minimum capital requirements.

Method: This research uses a case approach to analyze existing problems. There are differences in legal regulations that cause problems. implementation of sanctions and supervision that cannot be implemented properly. These indications will be analyzed to find solutions to existing problems.

Results and Discussion: While Indonesia has just recently started to create comparable safeguards for investors, the UK mandates that online lending platforms have explicit backup plans and reserves to protect consumers.

Research Implications: There are still regulatory loopholes that need to be filled, especially in the areas of data protection, transparency, and dispute resolution procedures, despite Indonesia's notable legislative advancements in the online lending sector, according to this report.

Originality/Value: Taking into account the local market's features and the degree of financial knowledge of the Indonesian populace, this study suggests that Indonesia implement some of the best practices from the UK regulatory system.
The Mediating Role of Strategic Intelligence in the Relationship Between Administrative Creativity and Decision-Making Styles in Jordanian Universities
Authors: Shaqra Rawan Khader Abu , Alsadi Mohammad 
Published: January 2025

Objective: The study aimed to identify the mediating role of strategic intelligence in the relationship between administrative creativity and decision-making styles in Jordanian universities.

Method: To achieve the study's goal, the predictive descriptive approach was used through the design of a research tool that included three main axes: strategic intelligence, administrative creativity, and decision-making styles. This tool was distributed to faculty members in Jordanian universities, with a total of 346 participants.

Results: The study results showed that the level of strategic intelligence among department heads was high. Additionally, it revealed that administrative creativity skills were also high.

Findings: The findings further indicated that department heads predominantly used rational decision-making styles compared to other styles. Moreover, strategic intelligence was found to mediate the relationship between administrative creativity and decision-making styles.