bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unmet Need for Sexual Rehabilitation after Acquired Brain Injury (ABI): A Cross-Sectional Study Concerning Sexual Activity, Sexual Relationships, and Sexual Rehabilitation after ABI
Authors: Ek Ann-Sofie , Holmström Charlotta , Elmerstig Eva 
Published: April 2023

AbstractIn relation to brain injury rehabilitation, research has stressed the importance of including sexuality issues due to increased risk for sexual dysfunctions after Acquired Brain Injury (ABI). This study aims to explore experiences after non-stroke ABI concerning individual and relational aspects of sexuality, received information about sexuality at rehabilitation, and gender differences. A postal nationwide survey was conducted in Sweden, 2018–2019. The sample included individuals who had participated in brain injury rehabilitation 2014–2016, response rate 40% (250/624). Among all participants 78% had resumed sexual activity, and there was a significant difference between males (84%, 118/140) and females (69%, 76/110, p = 0.004). Among all participants, 95% reported physical intimacy as important, 80% considered sex as important on an individual level, and 91% stated sexuality as important for the relationship (no gender differences). Significantly more females (52%) than males (22%) reported that they had tried sexual aids (p = 0.000), and more males (29%) than females (16%) reported that professionals addressed sexuality issues during brain injury rehabilitation (p = 0.024). However, only a few participants were offered specific sexual counseling during brain injury rehabilitation, such as individual counseling (3%), couples counseling (2%), and group counseling (3%). To conclude, the vast majority valued both individual and relational aspects of sex and sexuality highly, and more males than females had resumed sexual activity. Few had received information about sexuality after ABI, and even fewer females compared to males reported that the issue was raised during rehabilitation. Clinical implications are discussed in relation to sexual rehabilitation.
Thresholding methods in non-intrusive load monitoring
Authors: Precioso Daniel , Gómez-Ullate David 
Published: April 2023

AbstractNon-intrusive load monitoring (NILM) is the problem of predicting the status or consumption of individual domestic appliances only from the knowledge of the aggregated power load. NILM is often formulated as a classification (ON/OFF) problem for each device. However, the training datasets gathered by smart meters do not contain these labels, but only the electric consumption at every time interval. This paper addresses a fundamental methodological problem in how a NILM problem is posed, namely how the different possible thresholding methods lead to different classification problems. Standard datasets and NILM deep learning models are used to illustrate how the choice of thresholding method affects the output results. Some criteria that should be considered for the choice of such methods are also proposed. Finally, we propose a slight modification to current deep learning models for multi-tasking, i.e. tackling the classification and regression problems simultaneously. Transfer learning between both problems might improve performance on each of them.
Vertex transitivity and distance metric of the quad-cube
Authors: Jha Pranava K. 
Published: April 2023

AbstractThe quad-cube is a special case of the metacube that itself is derivable from the hypercube. It is amenable to an application as a network topology, especially when the node size exceeds several million. This paper presents the following welcome properties of the graph, relating to its structure: (1) vertex transitivity that facilitates the working of an algorithm meant for a “local” context in the global context as well, and (2) an exact formula for the distance metric, which leads to a precise result on the distance-wise vertex distribution of the graph and an exact formula for the average vertex distance. Remarkably, the vertex distribution of the quad-cube resembles, to a large extent, the vertex distribution of the twin copies of a hypercube. In a parallel study, the author recently reported similar results with respect to the dual-cube (Jha in J Supercomput 78:17758–17775, 2022)
What-it’s-like talk is technical talk
Authors: Owesen Erlend 
Published: April 2023

AbstractIt is common to characterise phenomenal consciousness as what it is like to be in a mental state. This paper argues that the ‘what-it’s-like’-phrase in this context has a technical meaning, i.e. a meaning for which the association to the relevant expression is peculiar to a theoretical community. The relevant theoretical community is philosophy and some parts of cognitive science, so on this view, only philosophers and cognitive scientists use the ‘what-it’s-like’-phrase in the way that is characteristic in the literature on phenomenal consciousness. This claim has important consequences. Firstly, I argue that the phrase says nothing informative about phenomenal consciousness. Secondly, I argue that the fact that non-philosophers use the phrase is not compelling evidence that they believe in phenomenal consciousness. These claims have further consequences for debates about phenomenal consciousness.
Nematode predatory ability of the fungus Duddingtonia flagrans affected by in vitro sequential exposure to ovine gastrointestinal tract
Authors: Céspedes-Gutiérrez Elizabeth , Aragón Diana Marcela , Gómez-Álvarez Martha Isabel , Cubides-Cárdenas Jaime Andrés , Cortés-Rojas Diego Francisco 
Published: April 2023

AbstractDuddingtonia flagrans is a nematophagous fungus employed as a biocontrol agent of gastrointestinal nematodes in ruminants. After oral ingestion and passage through the digestive tract of animals, this microorganism captures the nematodes in the feces. The drastic conditions of ruminant digestive tract could affect fungi chlamydospores and therefore biocontrol activity. The aim of this study was to evaluate in vitro the effect of four ruminant digestive segments on the concentration and nematode predatory ability of a Colombian native strain of D. flagrans. The sequential four-step methodology proposed evaluated conditions of the oral cavity, rumen, abomasum, and small intestine such as pH (2, 6, 8), enzymes (pepsin, pancreatin), temperature (39 °C), and anaerobiosis comparing short (7 h) and long (51 h) exposure times. The results showed that the nematode predatory ability of the fungi is affected by sequential exposure to gastrointestinal segments and this effect depends on the exposure time to those conditions. After short exposure (7 h) through the four ruminant digestive segments, the fungi had a nematode predatory ability of 62%, in contrast, after long exposure (51 h) the nematode predatory ability was lost (0%). Moreover, the number of broken chlamydospores was higher in the long-exposure assay.
Noninvasive Imaging OX40+ Activated T Cells Provides Early Warning of Rheumatoid Arthritis
Authors: Wen Gang , Lei Hongwei , Qi Baochang , Duan Shao , Xiao Zunyu , Han Chaozhe , Xia Yifei , Jing Chengwei , Liu Jianyu , Li Chao 
Published: April 2023

Abstract
Purpose
The goal of this study was to develop an imaging probe—IRDye-680RD-OX40 mAb—that can be used for noninvasive imaging and optical imaging of rheumatoid arthritis (RA). OX40/OX40 ligand (OX40L) interactions have been shown to exert potent costimulatory effects on T cell activation. Detectable change in T cell activation profiles was observed in early RA.

Methods
OX40 expression pattern was analyzed by flow cytometry. N-hydroxysuccinimide (NHS) esters are used to label proteins selectively on free amino groups of OX40 monoclonal antibody (mAb). Characterization of IRDye-680RD-OX40 mAb was measured and a fluorescence spectrum gathered. Cell binding assay was also performed between activated and naïve murine T cells. Longitudinal near-infrared fluorescence (NIRF) imaging of the probe was performed on day 8, day 9, day 10, and day 11 of adjuvant-induced arthritis (AIA) mouse model. Paw thickness and body weight were compared between the OX40 mAb and IgG injection groups.

Results
NIRF imaging with IRDye-680RD-OX40 mAb revealed strong OX40-positive responses with high specificity. Flow analysis showed that OX40 was specifically expressed on the surface of T cells in RP and spleen of AIA model. The AIA group was significantly differentiated from the control group at all time points with imaging monitoring. The region of interest (ROI) was in line with ex vivo imaging and biodistribution study. This study highlights the potential utility of the OX40 NIRF imaging as a new strategy for RA prediction and T cell monitoring.

Conclusion
The results provide evidence that IRDye-680RD-OX40 mAb detects organized T cells activation in early RA. The optical probe was capable of detection of RA pathogenesis. It identified transcriptional responses to RA that mediate its immune functions. Thus, it may be an ideal probe for RA imaging.

Graphical Abstract
Fatigue and Progressive Damage of Thin Woven CFRP Plates Weakened by Circular Holes
Authors: Heinzlmeier L. , Sieberer S. , Kralovec C. , Schagerl M. 
Published: April 2023

Abstract
Background
In order to design thin-walled components it is necessary to consider the presence of holes and their effects. For high performance composite structures, this is still an issue, since usually only coupons are used in experimental observations and the influence of free edges and the hole affects the fatigue behavior mutually.

Objective
This work aims to find, through experimental trials, an empirical model that can be used to describe and predict the damage propagation, originating from a circular hole.

Methods
A fatigue test series is performed and the damage initiation and propagation is monitored with three-dimensional digital image correlation, with which the occurring damage can be measured. Validation of the experimentally induced damage size measured with digital image correlation is performed intermediate with an in-situ measurement with active thermography and phased array ultrasonic. The novelty of this approach is that wide specimens are used, where the influence of the free edges on the hole does not occur.

Results
The progression of the detected damage over the test reflects the applied loads, where higher loads cause larger damage. For all defined load levels a similar damage propagation is identified, allowing to establish an empirical model and fit it to the test data.

Conclusion
The proposed empirical model provides a novel approach to describe and predict damage propagation originating from a circular hole in thin-walled composite plates. In addition, it is shown that the damage propagation ceases for the selected plate configuration and thus does not lead to a complete failure.
Haemato-biochemical, mutagenic, and histopathological changes in Oreochromis niloticus exposed to BTX
Authors: Sayed Alaa El-Din H. , Idriss Shaimaa K. , Abdel-Ghaffar Sary Kh. , Hussein Asmaa A. A. 
Published: April 2023

AbstractThe study of the DNA damage response in erythrocytes after exposure to volatile organic compounds (VOCs) can present evidence for its potential effect as genotoxic- biomarkers for environmental pollution. Although VOCs are dangerous pollutants, still little is known about hemotoxic, cytotoxic, and genotoxic effects of such pollutants on fish. We optimized an assay method for apoptosis and DNA damage in erythrocytes of adult tilapia fish after 15 days exposure to benzene (0.762 ng/L), toluene (26.614 ng/L), and xylene (89.403 ng/L). The highest level of apoptosis and DNA damage were recorded in benzene-exposed fish, as was the highest level of histopathological alterations in gills, liver, and kidney. The imbalance of the antioxidants profile explained the stress-case reported in exposed fish. These results suggest that hemotoxic, cytotoxic, genotoxic, and tissue damage were recorded after exposure to BTX in Oreochromis niloticus.
Environmental Conditions After Planting Affect the Expression of Differences in Tuber Formation of In Vitro-Derived Potato Plantlets from Different Ages and Cultivars
Authors: Lommen W. J. M. 
Published: April 2023

AbstractTo identify if and how the age of in vitro potato plantlets at planting affects the later tuber formation, an extensive pot experiment was performed under controlled conditions. In vitro-derived plantlets of different ages (14, 28, 42 and 56 days old at planting) and cultivars varying in maturity type (Gloria, very early; Bintje, mid-early; Elkana, late) were grown after planting for 10 weeks at photo/thermoperiods of 16 h (standard conditions) or 12 h (short-day conditions). Plants raised from older in vitro plantlets produced higher total dry weights, harvest index and tuber dry and fresh weights than plants from younger in vitro plantlets when grown under standard conditions after planting. By contrast, total and tuber dry weights were not affected by plantlet age when grown under short-day conditions. The number of tubers per plant increased with increase in in vitro plantlet age in the later cultivars and in the oldest age classes of the very early cultivar when plants were grown under standard conditions. Short-day conditions resulted in fewer, but larger tubers than standard conditions. Results support the ideas that (1) plants from older in vitro plantlets and earlier maturing cultivars are more advanced in the tuber formation process; however, this may benefit tuber yield only when plants are grown under conditions that are not strongly inducing tuberization, and (2) higher tuber numbers can be achieved by more below-ground nodes—as in older in vitro plantlets—and/or by later or less strong tuber induction—as in less inducing conditions (16-h vs. 12-h), later cultivars or younger in vitro plantlets.
Neuroimaging of hypophysitis: etiologies and imaging mimics
Authors: Kurokawa Ryo , Kurokawa Mariko , Baba Akira , Nakaya Moto , Kato Shimpei , Bapuraj Jayapalli , Nakata Yasuhiro , Ota Yoshiaki , Srinivasan Ashok , Abe Osamu , Moritani Toshio 
Published: April 2023

AbstractHypophysitis is an inflammatory disease affecting the pituitary gland. Hypophysitis can be classified into multiple types depending on the mechanisms (primary or secondary), histology (lymphocytic, granulomatous, xanthomatous, plasmacytic/IgG4 related, necrotizing, or mixed), and anatomy (adenohypophysitis, infundibulo-neurohypophysitis, or panhypophysitis). An appropriate diagnosis is vital for managing these potentially life-threatening conditions. However, physiological morphological alterations, remnants, and neoplastic and non-neoplastic lesions may masquerade as hypophysitis, both clinically and radiologically. Neuroimaging, as well as imaging findings of other sites of the body, plays a pivotal role in diagnosis. In this article, we will review the types of hypophysitis and summarize clinical and imaging features of both hypophysitis and its mimickers.
The Swallowable Intragastric Balloon Combined with Lifestyle Coaching: Short-Term Results of a Safe and Effective Weight Loss Treatment for People Living with Overweight and Obesity
Authors: Jense Marijn T.F. , Palm-Meinders Inge H. , Sanders Boy , Boerma Evert-Jan G. , Greve Jan Willem M. 
Published: April 2023

Abstract
Background
Some patients with overweight or obesity are not eligible for surgery according to international guidelines or do not wish a surgical intervention. For these patients, different treatment options are being explored. In this study, we examined the effectiveness of the swallowable intragastric balloon (IB) combined with lifestyle coaching, in patients living with overweight and obesity.

Method
A retrospective data study was conducted on patients with a swallowable IB placement between December 2018 and July 2021, combined with a 12-month coaching program. Before balloon placement, patients underwent multidisciplinary screening. The IB was swallowed and filled with fluid once in the stomach and naturally excreted around 16 weeks.

Results
A total of 336 patients, 71.7% female, were included with a mean age of 45.7 (±11.7) years. Mean baseline weight and BMI were 107.54 (±19.16) kg and 36.1 (±5.02) kg/m2. After 1 year, the mean total weight loss was 11.0% (±8.4). The mean placement duration was 13.1 (±2.82) min, and in 43.7%, a stylet was used to facilitate placement. The most common symptoms were nausea (80.4%) and gastric pain (80.3%). In the majority of patients, complaints were resolved within a week. The early deflation of the balloon occurred in 8 patients (2.4%) of which one showed symptoms suggesting a gastric outlet obstruction.

Conclusion
Given the low rate of long-term complaints while providing a positive effect on weight loss, we conclude that the swallowable intragastric balloon, combined with lifestyle coaching, is a safe and effective treatment option for patients living with overweight and obesity.

Graphical Abstract
Economic development, female wages and missing female births in Spain, 1900–1930
Authors: Echavarri Rebeca , Beltrán Tapia Francisco J. 
Published: April 2023

AbstractFocusing on Spain between 1900 and 1930, a period characterised by significant structural transformations and rapid economic growth, this article shows that the sex ratio at birth (SRB) was abnormally high, at least until the 1920s. Apart from questioning whether female under-registration and different mortality environments alone can explain the results reported here, our analysis of regional information indicates that SRBs were higher in provinces where the economic structure was dominated by agriculture and manufacturing (relative to the service sector). In addition, exploiting the annual variation in low-skilled wages at the province level makes it possible to distinguish between the roles played by under-registration and outright neglect: while higher wages could increase the opportunity cost of registering a female birth (and therefore result in higher SRBs), they could also reduce the pressure to neglect female babies (and therefore result in lower SRBs). We find evidence of both effects (income and opportunity cost) of wages on SRBs between 1914 and 1920 in Spain, a period in which WWI arguably subjected the Spanish economy to an exogenous demand shock. These two effects, however, imply very different discriminatory practices. In fact, on average, the income effect was larger than the effect arising from the opportunity cost, which supports the idea that female neglect around birth was more prevalent than previously assumed during the early twentieth century in Spain. As expected, the relationship between wages and the SRB vanished during the 1920s, along with the unbalanced SRB. These results stress that gender discrimination around birth does not necessarily disappear with economic growth unless this process is accompanied by expanded labour opportunities for women.
Memnon in the Middle Ages: The Reception of a Homeric Hero
Authors: Dean Trevor 
Published: April 2023

AbstractMemnon, the mythic king of Ethiopia killed by Achilles during the Trojan War, had a double or fused identity in classical antiquity: both Asian and African for Greek and Roman writers because of his parentage and because of the geographical indeterminacy of ‘Aithiopia’ and of ‘India’, but definitely black-skinned for Roman writers. How was this figure received in medieval texts and images? This paper tracks Memnon through three textual genres from the twelfth to the fifteenth century – commentaries on Ovid, catalogues of famous men, histories of the Trojan War – and charts the ways in which his classical identity was overlaid and transformed by pro-Trojan sentiment, chivalric heroization and Christian sacrificial thinking.
A Trained Humanoid Robot can Perform Human-Like Crossmodal Social Attention and Conflict Resolution
Authors: Fu Di , Abawi Fares , Carneiro Hugo , Kerzel Matthias , Chen Ziwei , Strahl Erik , Liu Xun , Wermter Stefan 
Published: April 2023

AbstractTo enhance human-robot social interaction, it is essential for robots to process multiple social cues in a complex real-world environment. However, incongruency of input information across modalities is inevitable and could be challenging for robots to process. To tackle this challenge, our study adopted the neurorobotic paradigm of crossmodal conflict resolution to make a robot express human-like social attention. A behavioural experiment was conducted on 37 participants for the human study. We designed a round-table meeting scenario with three animated avatars to improve ecological validity. Each avatar wore a medical mask to obscure the facial cues of the nose, mouth, and jaw. The central avatar shifted its eye gaze while the peripheral avatars generated sound. Gaze direction and sound locations were either spatially congruent or incongruent. We observed that the central avatar’s dynamic gaze could trigger crossmodal social attention responses. In particular, human performance was better under the congruent audio-visual condition than the incongruent condition. Our saliency prediction model was trained to detect social cues, predict audio-visual saliency, and attend selectively for the robot study. After mounting the trained model on the iCub, the robot was exposed to laboratory conditions similar to the human experiment. While the human performance was overall superior, our trained model demonstrated that it could replicate attention responses similar to humans.
Mehr oder weniger punitiv?
Authors: Beineke Christoph , Schmidt Sabrina , Wen Sebastian 
Published: April 2023

ZusammenfassungDer Beitrag rückt die Hypothese in den Fokus, dass die Fachkräfte der Sozialen Arbeit im Zuge der sozialpolitischen Wende hin zum aktivierenden Sozialstaat vermehrt durch punitive Einstellungen gekennzeichnet sind. In diesem Kontext verfolgt diese Studie das Ziel, empirisch zu beforschen, wie häufig und warum punitive Einstellungen unter angehenden Fachkräften der Sozialen Arbeit und in der Allgemeinbevölkerung mit soziodemografisch ähnlicher sozialer Lage vorkommen. Die Ergebnisse untermauern die Hypothese punitiver Einstellungen in der Sozialen Arbeit nur teilweise. Zwar zeigen sich unter angehenden Fachkräften der Sozialen Arbeit durchaus punitive Einstellungen, insgesamt treten sie im Vergleich zur entsprechenden Referenzgruppe der Allgemeinbevölkerung jedoch seltener und weniger stark auf. Die Befunde stellen zudem die politische Einstellung und die soziale Herkunft als Determinanten punitiver Einstellungen heraus.