bluuebunny/crossref_metadata_2025_split huggingface dataset:
Life in Care Homes during the Covid-19 Pandemic
Authors: Balard Frédéric , Caradec Vincent , Castra Michel , Chassagne Aline , Clavandier Gaëlle , Launay Pauline , Schrecker Cherry , Trimaille Hélène 
Published: January 2023

Fondé sur des entretiens réalisés avec 37 résidents vivant dans 15 établissements d’hébergement pour personnes âgées dépendantes (Ehpad), cet article se propose d’analyser leurs expériences variées du premier confinement. Dans un premier temps, il montre que l’expérience du confinement a pris des formes différentes en fonction des modes d’habiter en Ehpad. Ceux qui vivaient repliés dans leur chambre voient peu de différences avec la vie d’avant. Ceux qui habitaient l’Ehpad en s’appropriant les espaces collectifs tendent à percevoir le confinement comme une privation de ces espaces. Enfin, ceux qui étaient tournés vers l’extérieur de l’établissement insistent plutôt sur l’absence de liberté de circuler en dehors de l’Ehpad qui a marqué la période. Dans un second temps, l’article explore trois autres facteurs qui éclairent également les expériences du confinement : les modalités de confinement mises en place par l’Ehpad dans lequel ils résident, les ressources occupationnelles ou relationnelles que les Ehpad ont pu mobiliser et la trajectoire antérieure des résidents.
Itinérances politiques et éducatives franco-espagnoles. « Voir ce qui doit être vu » : les trois voyages d'Henri Wallon en Espagne républicaine de 1936 à 1938
Authors: Rodriguez Mari Carmen 
Published: January 2023

De 1936 à 1938, Henri Wallon, psychologue de l'enfance, enseignant à la Sorbonne, puis au Collège de France, se rend à trois reprises dans une République espagnole en guerre. Comme pour les membres de sa génération qui en ont fait l'expérience, le « voyage de guerre » en Espagne est un outil de formation multiple et un vecteur de circulations transnationales. La zone républicaine de 1936 à 1939 est une destination où convergent des militants antifascistes, conscients de la portée internationale du conflit, ainsi que les passeurs de réformes éducatives. En effet, ce territoire constitue un laboratoire de l'« École nouvelle », héritier d'un long parcours d'échanges depuis le XVIIIe siècle entre élites libérales pour lesquelles l'éducation est un partage fondateur et émancipateur. Cette contribution tente de questionner ces échanges à la lumière de l'itinérance politique et éducative de Wallon durant ses trois séjours, entre engagement marxiste et antifasciste, action humanitaire et observation du patrimoine d'« Éducation nouvelle » en Espagne avant sa disparition.
Quels sens pour les savoirs scolaires en démocratie ? Approches, lectures, défis
Authors: Roelens Camille 
Published: January 2023

L’article se propose de traiter de la question du sens des savoirs scolaires en démocratie. Nous identifions deux voies réflexives privilégiées permettant de progresser vers l’horizon d’une intelligibilité plus assurée dans ce domaine – l’épistémologie des savoirs scolaires et la philosophie politique de l’éducation – et tentons un dialogue avec la première depuis un ancrage dans la deuxième. Le premier temps de notre développement est dédié aux contributions respectives de Brigitte Frelat-Kahn, de Marie-Claude Blais, Marcel Gauchet et Dominique Ottavi, et enfin de Pierre Statius. Nous reconstituons ainsi un moment de réflexion important sur les enjeux scolaires dans la démocratie française contemporaine. Le second moment de notre développement identifie trois inspirations majeures – deweyenne, bachelardienne et tocquevillienne – pour penser notre objet. Nous montrons donc, en dialogue avec les travaux de Michel Fabre, comment la notion de problématicité du monde démocratique peut être un guide précieux pour aborder deux questions socialement et politiquement vives pour penser les savoirs scolaires en démocratie : la question individualiste et la question libérale.
Usages et impacts des espèces arborescentes dans les exploitations cacaoyères de l’Indénié-Djuablin, Côte d’Ivoire
Authors: Kougbo Ménéké Distel , Djah François Malan , Diop Amadou Lamine , Amenan Sylvie Konan , Dogba Mathieu 
Published: January 2023

Les espèces arborescentes ont toujours occupé une importante place dans les cacaoyères en zone tropicale. Cependant, leur survie est menacée à cause de l’évolution des pratiques culturales. Cette étude vise à connaître les interactions entre les agriculteurs de l’Indénié-Djuablin (Côte d’Ivoire) et les espèces arborescentes qu’ils épargnent ou introduisent dans leurs cacaoyères. Pour ce faire, un inventaire de ces espèces a été effectué à l’intérieur de 54 cacaoyères sélectionnées sur la base de la superficie et de la densité d’espèces arborescentes. Une enquête semi-structurée individuelle a été ensuite menée auprès des propriétaires des cacaoyères afin de connaître comment ils perçoivent et utilisent les espèces trouvées dans leurs plantations. Dans ces cacaoyères, il a été inventorié 63 espèces arborescentes employées dans quatre catégories d’usages : alimentaire, bois d’œuvre, médicinal et bois de chauffe. Par ailleurs, 64,06 % de ces ligneux sont perçus comme ayant des incidences positives ou négatives sur le développement des cacaoyers. Les bois d’œuvre comme le Tiama (Entandrophragma angolense), le Bété (Mansonia altissima) et l’Iroko (Milicia excelsa) sont appréciés pour l’excellent ombrage bénéfique aux jeunes cacaoyers et l’amélioration de la fertilité du sol tandis que les plantes médicinales comme l’Emien (Alstonia boonei), l’Ilomba (Pycnanthus angolensis) et l’Akpi (Ricinodendron heudelotii) sont perçues comme créant un ombrage excessif et comme hôtes potentiels de parasites des cultures. Certains ligneux néfastes au développement des cacaoyers sont donc maintenus dans les cacaoyères pour des usages précis. La prise en compte d’un tel aspect dans tout projet d’agroforesterie permettrait de concilier durablement production agricole, conservation de la diversité végétale et valorisation de la ressource.
The fate of surplus embryos in the setting of assisted reproductive technology
Authors: Agung Sentosa I Gusti Agung Ngurah , Ayuandari Sarrah , Rosyidah Rafhani , Dewanto Agung 
Published: January 2023

Objective:
To identify the attitudes of infertile couples toward their surplus frozen embryos.

Methods:
This study was according to PRISMA-ScR as the guideline for scoping review. Studies that assessed the attitudes of patients or infertile couples who had surplus embryos were included. We conducted systematic searches in English studies from April 2011-April 2021 using 7 databases: PubMed, Science Direct, EBSCO, Scopus, the Cochrane Library, Sage Journals, and Google Scholar. Data were charted based on author, year of publication, country, purpose, data collection, key findings, and research focus/domain.

Results:
A total of 37 research articles were included in the analysis. Their attitudes encompassed: supporting the donation of the surplus embryos for both research and reproductive purposes, continuing to store the frozen embryos, and disposing of the surplus embryos.

Conclusions:
Most of the infertile patients support donating their surplus embryos for research and reproductive purposes.
Embryo quality and chromosomal abnormality in embryos from couples undergoing assisted reproductive technology using preimplantation genetic screening
Authors: Niusha Mina , Rahmani Seyed Ali , Kohan Leila , Sadeghi Ladan , Nouri Mohammad , Nejabati Hamid Reza 
Published: January 2023

Objective:
To detect common chromosomal aneuploidy variations in embryos from couples undergoing assisted reproductive technology and preimplantation genetic screening and their possible associations with embryo quality.

Methods:
In this study, 359 embryos from 62 couples were screened for chromosomes 13, 21, 18, X, and Y by fluorescence insitu hybridization. For biopsy of blastomere, a laser was used to remove a significantly smaller portion of the zona pellucida. One blastomere was gently biopsied by an aspiration pipette through the hole. After biopsy, the embryo was immediately returned to the embryo scope until transfer. Embryo integrity and blastocyst formation were assessed on day 5.

Results:
Totally, 282 embryos from 62 couples were evaluated. The chromosomes were normal in 199 (70.57%) embryos and abnormal in 83 (29.43%) embryos. There was no significant association between the quality of embryos and numerical chromosomal abnormality (P=0.67).

Conclusions:
Embryo quality is not significantly correlated with its genetic status. Hence, the quality of embryos determined by morphological parameters is not an appropriate method for choosing embryos without these abnormalities.
A novel herbal combination ameliorates ovarian dysfunction and regulates altered biochemical parameters in rats with letrozole-induced polycystic ovary syndrome
Authors: Shailajan Sunita , Menon Sasikumar , Singh Swati , Patil Yugandhara 
Published: January 2023

Objective:
To investigate the potential activity of novel herbal combination and novel herbal formulation (syrup) in female Sprague Dawley rats with letrozole-induced polycystic ovary syndrome (PCOS).

Methods:
Forty-two rats were randomly divided into seven groups with six rats in each group. Group 1 received 0.5% carboxy methylcellulose orally for 37 days and served as the normal control group. Group 2 was orally administered with letrozole of 1 mg/kg for 21 days and served as the PCOS induction group without treatment. Group 3 to 7 were administered with letrozole of 1 mg/kg for 21 days orally to induce PCOS, and then respectively received clomiphene citrate at 1 mg/kg, 100 and 200 mg/kg of novel herbal combination, 200 mg/kg of novel herbal formulation (syrup), and 400 mg/kg of marketed formulation of Pushyanuga churna, once daily for 15 days. Effects of the novel herbal combination and its syrup formulation were evaluated on the hormonal profile, the levels of antioxidants, the lipid profile and on the ovarian morphology, using letrozole-induced PCOS model in rats.

Results:
Letrozole caused alterations in hormonal levels and lipid levels similar to PCOS and ovarian histology showed presence of ovarian cysts confirming the induction of PCOS in rats. On treatment with the novel herbal combination and its syrup formulation in PCOS-induced rats, the altered hormonal and lipid profiles showed significant recovery to normal levels. Ovarian histology confirmed the restoration of folliculogenesis in the PCOS-induced rats. The treatment with the syrup formulation of novel herbal combination was found to be more effective than novel herbal combination and showed better recovery in various parameters evaluated. The results of the study, however, suggested that treatment with novel herbal combination and its syrup formulation provided minimal protection against oxidative stress caused due to the induction of PCOS.

Conclusions:
The integrated approach for management of PCOS is to counterbalance the limitations associated with modern therapy. Both the novel herbal combination and the syrup formulation of novel herbal combination show efficacy in the management of PCOS in rats and restore folliculogenesis in the ovary. The syrup formulation of novel herbal combination is most effective in the management of PCOS and shows potential to be developed as an adjuvant therapeutic agent.
Effects of N-acetylcysteine on growth, viability and reactive oxygen species levels in small antral follicles cultured in vitro
Authors: Cordeiro Efigênia B. , Silva Bianca R. , Paulino Laís R. F. M. , Barroso Pedro A. A. , Barrozo Laryssa G. , de Lima Neto Miguel F. , Silva José R. V. 
Published: January 2023

Objective:
To investigate the effects of different concentrations of N-acetylcysteine on follicular growth and morphology, as well as on viability, levels of reactive oxygen species (ROS) and meiotic progression of oocytes from in vitro cultured bovine early antral follicles.

Methods:
Isolated early antral follicles (about 500 μm) were cultured in TCM-199+ alone or supplemented with 1.0, 5.0 or 25.0 mM N-acetylcysteine at 38.5 °C with 5% CO2 for 8 days. Follicle diameters were evaluated at day 0, 4 and 8 of culture. At the end of culture, the levels of ROS, chromatin configuration and viability (calcein-AM and ethidium homodimer-1 staining) were investigated in the cumulus-oocyte complexes. Comparisons of follicle diameters between treatments were performed. Data on percentages of morphologically normal follicles, growth rates and chromatin configuration in different treatments were compared.

Results:
An increase in follicular diameters after culture in all treatments was observed, except for follicles cultured with 25.0 mM N-acetylcysteine. Fluorescence microscopy showed that oocytes cultured in all treatments were stained positively with calcein-AM, and that 5.0 mM N-acetylcysteine reduced fluorescence for ethidium homodimer-1. Intracellular levels of ROS in oocytes from follicles cultured with 1.0 mM N-acetylcysteine showed a significant reduction compared to other treatments. The presence of N-acetylcysteine in culture medium did not influence the rates of oocyte at the germinal vesicle stage.

Conclusions:

N-acetylcysteine at concentrations of 1.0 and 5.0 mM reduces ROS levels and staining for ethidium homodimer-1 in in vitro cultured follicles, respectively, while 25.0 mM N-acetylcysteine decreases follicular growth and the percentages of continuously growing follicles.
Assessment of the effect of two regimens of milrinone infusion in paediatric patients with pulmonary artery hypertension undergoing corrective cardiac procedure
Authors: Prajapati Mrugesh , Patel Jigar , Patel Hasmukh , Gandhi Hemang , Singh Guriqbal , Patel Pravin 
Published: January 2023

Background :
The aim of the study was to compare the effect of two different regimens of milrinone in pediatric patients with pulmonary artery hypertension (PAH) undergoing corrective procedure.

Materials and Methods :
This randomized prospective study included 100 pediatric patients undergoing corrective cardiac surgeries. Group E: Milrinone was started as infusion 0.5 μg/kg/min without a loading dose after induction of anesthesia and continued as infusion 0.5–0.75 μg/kg/min in the pediatric cardiac surgical intensive care unit (PSICU). Group L: Milrinone was started as a loading dose 50 μg/kg over 10 min before weaning from cardiopulmonary bypass (CPB) followed by infusion 0.5–0.75 μg/kg/min in the PSICU. We compared heart rate, mean arterial blood pressure, central venous pressure, cardiac index (CI), mean pulmonary arterial pressure (MPAP), serum lactate level, urine output, vasoactive inotropic score, mechanical ventilation duration, and intensive care unit (ICU)- and hospital length of stay between the groups.

Results :
There was an increase in mean arterial blood pressure, CI, and urine output in Group E compared to Group L (P < 0.05). MPAP, serum lactate level, and requirement of inotropes and vasopressors were lower in Group E compared to Group L (P < 0.05). Mechanical ventilation duration, ICU, and hospital length of stay were shorter in Group E than Group L (P < 0.05).

Conclusions :
Early use of milrinone in patients with PAH undergoing corrective cardiac surgeries improved CI and mean arterial pressure, decreased MPAP, improved urine output, decreased serum lactate level, and decreased requirement of inotropes and vasopressors after weaning from CPB compared to the milrinone bolus group.
Effectiveness of mHealth for modification of dietary habits and physical activity among individuals at risk or suffering from noncommunicable diseases in primary healthcare settings in South East Asian Region countries – A systematic review and meta-analysis
Authors: Banerjee Bratati , Dutt Debashis , Saha Indranil , Paul Bobby , Lachyan Abhishek Shivanand 
Published: January 2023

Background:
Noncommunicable diseases (NCDs) are increasing, for which some behavioral risk factors are major concerns. mHealth has been found to be effective in changing these behavioral patterns.

Objective:
To assess effectiveness of mHealth technology in modification of dietary habits and physical activity, among individuals having NCDs or their risk factors, in primary healthcare settings in South East Asian Region Countries.

Materials and Methods:
A systematic review and meta-analysis was done with the primary outcome as effectiveness of mHealth for improving dietary practices and increasing physical activity. Articles were retrieved from PubMed, Cochrane Central, Google Scholar, and Pre-print servers followed by forward and backward searching. Quality and risk of bias of included studies were assessed. Meta-analysis was performed using RevMan v. 5.4.1 software. Heterogeneity was tested using χ
2 test and measured using I
2 statistic, with Forest plots as the final outcome.

Results:
Nine publications from seven studies, of which seven were conducted in India and two in Bangladesh, qualified for the review. All studies used varied mHealth interventions. Most studies reported beneficial effects in reducing inadequate/improper diet and insufficient/improving physical activity, at community/workplace settings, except two studies reporting no apparent impact, both being from Bangladesh. Meta-analysis revealed statistically significant differences between intervention and control groups for pooled estimates of reduced dietary energy and increased fruits/vegetables. Although heterogeneity is absent between studies considered for fruits/vegetables, both studies were compromised in quality and bias. Studies on dietary energy intake had high statistical heterogeneity, in addition to having high risk of bias. Hence, the results need to be interpreted with caution. No effect was observed on increasing physical activity.

Conclusion:
mHealth interventions have huge potential to facilitate behavior change. However, more research is needed before its potential scale-up.
A 10-year review of the visual outcomes of early versus late pars plana vitrectomy in eyes with dropped lens fragment or nucleus during phacoemulsification
Authors: Farrahi Fereydoun , Kasiri Ali , Feghhi Mostafa , Darvishi Dastgerdi Malihe 
Published: January 2023

Background: Pars plana vitrectomy (PPV) is a routine surgical option for the removal of dropped lens fragment or nucleus in the vitreous cavity due to complicated cataract surgery; however, its optimal timing is controversial. Therefore, we aimed to determine the visual outcomes of early versus late PPV in eyes with dropped lens fragment or nucleus due to complicated phacoemulsification cataract surgery.
Methods: This descriptive-analytical retrospective study collected data of patients who underwent early (less than or equal to 1 week) versus late (> 1 week) PPV for the management of dropped lens fragment or nucleus resulting from complicated phacoemulsification cataract surgery over a 10-year period at Imam Khomeini Tertiary Referral Hospital, Ahvaz, Iran. Demographic characteristics, the interval between complicated phacoemulsification and PPV, pre- and postoperative intraocular pressures, best-corrected distance visual acuity (BCDVA), and postoperative complications were extracted from each patient’s record.
Results: Fifty-one eyes of 51 patients with a mean (standard deviation [SD]) age of 64.66 (6.54) years and a male-to-female ratio of 33 (64.7%) to 18 (35.3%) were included over 10 years. The mean (SD) BCDVA before PPV was 1.87 (0.53) logarithm of the minimum angle of resolution (logMAR), which improved significantly to 0.54 (0.46) logMAR at the final postoperative visit (P < 0.001). The mean (SD) BCDVA was significantly better after early PPV than after late PPV (0.41 [0.30] versus 0.62 [0.52] logMAR; P < 0.05). There was no significant difference in the final BCDVAs among the three methods of lens fragment removal (P > 0.05). The rates of post-PPV complications were as follows: 29 (56.9%) eyes with corneal edema, 16 (31.4%) eyes with uveitis, 10 (19.6%) eyes with cystoid macular edema, 8 (15.7%) eyes with rhegmatogenous retinal detachment, and 8 (15.7%) eyes with other complications (optic nerve atrophy, choroidal neovascularization, vitreous hemorrhage, or epiretinal membrane formation). No significant differences were observed in the rates of complications according to the time interval between complicated phacoemulsification and PPV (all P > 0.05). The frequency of corneal edema was significantly higher when removing lens fragments using the trans-limbal method than using the other methods (P < 0.05), yet the rates of other complications were comparable among the three methods of lens fragment removal (all P > 0.05).
Conclusions: Early PPV and removal of a dropped lens fragment or nucleus resulting from complicated phacoemulsification cataract surgery are recommended to achieve better visual outcomes. Future studies with longer follow-up, greater sample sizes, and analysis of other parameters of visual function, such as contrast sensitivity, visual field, color vision, and stereopsis, could provide more conclusive results and help verify our preliminary findings.
Annual cycle of hygroscopic properties and mixing state of the suburban aerosol in Athens, Greece
Authors: Spitieri Christina , Gini Maria , Gysel-Beer Martin , Eleftheriadis Konstantinos 
Published: January 2023

Abstract. The hygroscopic properties of atmospheric aerosol were
investigated at a suburban environment in Athens, Greece, from August 2016
to July 2017. The growth factor distribution probability density function (GF-PDF) and mixing state were determined with a hygroscopicity tandem
differential mobility analyser (HTDMA). Four dry particle sizes
(D0) were selected to be analysed in terms of their hygroscopic
properties at 90 % relative humidity. The annual mean GFs for D0 = 30, 50, 80 and 250 nm were found to be equal to 1.28, 1.11,
1.13 and 1.22, respectively. The hygroscopic growth spectra were divided
into two distinct hygroscopic ranges: a non- and/or slightly hygroscopic mode
(GF < 1.12) and a moderately hygroscopic mode (GF > 1.12), which are
representative of a suburban environment influenced by local/urban emissions
and background aerosol. The standard deviation σ of the GF-PDF was
employed as a measure of the mixing state of ambient aerosol. The 30 nm
particles were mostly internally mixed, whereas larger particles were found
to be externally mixed, either with a distinct bimodal structure or with
partly overlapping modes. Cluster analysis on the hourly dry number size
distributions was performed to identify the link between aerosol
hygroscopicity and aerosol emission sources and formation processes. The
size distributions were classified into five groups, with the “mixed urban
and regional background” aerosol (67 %) and the “fresh traffic-related
particles” from the neighbourhood urban area (15 %) accounting for more
than 80 % of the results. The hygroscopic properties for 50 and 80 nm
were found to be similar in all cases, indicating particles of similar
nature and origin across these sizes. This was also confirmed through the
modal analysis of the average number size distributions for each cluster;
the 50 and 80 nm particles were found to belong to the same Aitken mode
in most cases. The 250 nm particles (i.e. accumulation mode) were generally
more hygroscopic than Aitken particles but less hygroscopic than the 30 nm
particles (nuclei mode).