bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymorphism of VDR (Bsml) gene in patients with atopic dermatitis
Authors: Garibeh E. 
Published: December 2022

Objective — to study the significance of the BsmI (rs1544410) gene of the VDR as a genetic molecular marker of the risk of atopic dermatitis (AD) development.
Materials and methods. The study included 54 patients with atopic dermatitis (the main group). The control group consisted of 32 people. All of the participants of this study lived in Podilliya region and had Ukrainian origin. The method of allele detection is based on the polymorphism of the length of restriction fragments that are obtained after treatment with certain restriction enzymes. BsmI polymorphism was studied, the international polymorphism code is rs1544410. Correct distribution of genotype frequencies was determined in accordance with Hardy—Weinberg’s law. Statistically significant differences were considered at p < 0.05.
Results and discussion. Analysis of the genotypes of single nucleotide polymorphism rs1544410 of VDR gene in patients with atopic dermatitis showed the predominance of the heterozygous variant (G/A). However, the proportion of allele A reached (47.2 ± 3.7) %, which may indicate a significant number of people with increased risk of atopic dermatitis development. According to our study of the single nucleotide polymorphism of the BsmI gene of the VDR among the subjects of the control group, the percentage of A/A-­genotype carriers was significantly lower than that of individuals with G/G­ (р = 0.028) and G/A-genotype (р = 0.023). While comparing the distribution of genotypes and alleles of single-nucleotide polymorphism BsmI VDR gene among individuals of the main and the control groups, we noted that allele A was more common in patients with atopic dermatitis (47.2 vs. 39.07 %, (OR 1.412; 95 % SI 0.203—0.978; р = 0.271). According to the obtained data, the carriers of the A/A-genotype dominated among the patients with severe atopic dermatitis, in contrast to the patients with a moderate course of the disease in whom G/A-genotype predominated. Carriers of the G/A- and G/G-genotypes also predominated among the patients with a mild course of the disease. Their number was significantly higher than that of the patients with the A/A-genotype (p < 0.05).Conclusions. Polymorphism of the VDR rs1544410 gene may be associated with an increased risk of atopic dermatitis development. Carriers of A/A-genotype of VDR rs1544410 gene are more common among patients with atopic dermatitis than among healthy persons of the control group.
Nigerian Supreme Council for Islamic Affairs and the Quest for Unity of Muslim Ummah in Nigeria
Authors: Suberu Ibrahim 
Published: December 2022

Abstract
The emergence of Islamic organizations during the colonial era caused disunity among the Muslim Ummah in Nigeria. The quest to coordinate the affairs of these organizations and to unite the Muslim Ummah nationally under one umbrella led to the establishment of the Nigerian Supreme Council for Islamic Affairs (NSCIA) in 1973. This study, therefore, examines the role of NSCIA in addressing the challenges of disunity confronting the Muslim Ummah in Nigeria. Data were collected from oral interviews, questionnaires and secondary sources. A multidisciplinary approach was adopted using a combination of historical, phenomenological and sociological methods of data analysis. The theoretical framework is built on the theory of Asabiyyah by Ibn Khaldun and the theory of structural functionalism. The study discovered that the need to protect Islamic faith from colonial influence gave rise to the emergence of Islamic organizations in Nigeria. It is also discovered that Nigerian Muslims are divided along ethnic, regional and organizational lines. The study shows that despite the establishment of NSCIA in 1973, to foster unity, there are still issues bothering on disunity among the Muslim Ummah in Nigeria. Perpetuation and nothernization of the council's leadership is discovered to be a factor responsible for the inefficiency of the Council to unite the Ummah. This work recommends a review of the constitution of NSCIA for effectiveness. It also suggests rotation of its headship and that serious effort should be made by the Council at cultivating the spirit of unity among Muslims Ummah.
Effect of COVID -19 Pandemic on Mental Health of Students: A Contemporary Literature Review
Authors: Gyawali Kalpana 
Published: December 2022

The globally increasing trend of COVID -19 pandemic has got worldwide attention from several nations. Along with physical health, pandemic diseases have shown a tremendous negative impact on mental health in the general population throughout the world. To find out the impact of this pandemic on the mental health of students, a systematic review of different national and international literatures was carried out to complete this study. Elevated anxiety, depression, stress, and sleeping disorder were found as the major mental disorders among the students. Most of the results of reviewed studies were based on online survey. In Nepalease context studies on the impact of Covid -19 on mental health are very limited, hence the findings might be useful to explore the possible mental problems among the Nepalese students; and the result will be helpful to follow the necessary further steps to minimize the COVID-19 induced mental problems among the targeted group.
Analyzing the Educational Attainment of People in Nepal from Gender Perspective
Authors: Karki Rita Devi , Karki Tek Mani 
Published: December 2022

Education is a key tool for human civilization but many people are deprived of it and do not have equal chance to achieve it from gender point of view in society, though everyone has an equal right to get it. In this context, this study tries to explore the literacy status, educational attainment. The major concern of preparing this article was to study this issue extracting the data from two immediate past censuses of Nepal and analysing them by using the Microsoft Excel programme. Humanities and Arts, Business and Administration, Education, Science, and Social and Behavioural Science are supposed to be more selected subjects of study for both males and females at the national level. More gender gap in terms of literacy and level of education seems to occur though the level of education increases in all provinces.
Factors Influencing Head Teacher's Leadership: A Case of Community School in Kathmandu Valley
Authors: Sherpa Dawa , Baraily Khagendra 
Published: December 2022

This study aimed to explore the factors influencing leadership of head teacher. For this purpose, interpretative phenomenology was employed. Five head teachers having more than ten years' experience in different community secondary schools of Kathmandu valley were selected as participants for their lived experience and perception through purposive sampling. Information was collected through participants by in-depth interviews and semi-structured questionnaire to draw the perception and experience of the participants. In interviews, we attempted to interpret respondents' explanations, experiences, struggles, and evidences related to head teacher. Interviews were transcribed as verbatim and coded to generate themes. Themes were analyzed with reference to the essence of transformative leadership theory to reach in conclusion. The study finding showed that size of organization, level of interaction, decision making skill, problem solving skills, and team efforts are influencing factors for effective leadership. Head teacher’s leadership can be positively influenced in small organization but professional development of staffs can be negatively impacted. Frequent collaboration among stakeholders and interpersonal relationship among staff influences the leadership of head teacher positively. The tactful leadership skills for problem solving inspired the head teacher to strengthen the capacity of the organization along with team effort. Thus, the leadership of head teacher in community school needs to be sensitized to apply appropriate size based on stakeholder. The intensity of collaboration is required to be maintained with the principles of rich communication and team effort.
Spectrum of endocrine disorders in a hospitalized patient in a Tertiary University Hospital, Nepal
Authors: Yadav G. , Paudel G. , Gautam A. , Yadav R. , Khatiwada P. , Raut P. , Guragain P. , Chaturvedi M. , Maskey R. 
Published: December 2022

Background: The epidemiological spectrum of endocrine disorders in hospitalized patients is not much explored in developing countries. Therefore, the spectrum to visualize a complete picture of the endocrine-related disease is still missing.
Aims: The study aims to find the spectrum of endocrine-related-disorders in a hospitalized patient, characterize demographic variables, and the duration of hospital stay of patients.
Methods: This was a retrospective study of medical records of admitted cases between January 2014 to December 2018 in the Medicine Ward of BPKIHS. Records were retrieved from the Medical office and were entered into Excel and then transferred to SPSS and were analysed.
Result: Out of 26,590 admitted cases,1141 (4.3%) had endocrine-related-disease. This includes 565 males and 576 females (1.02: 1 ratio) with an overall mean age of 52.81 ± 16.21 years and median (IQR) age 53 (42-64) years. Among which 904 (79.2%) had Diabetes mellitus, 118 (10.3%) had Metabolic Disorders, 38 (3.3%) had Disorders of Thyroid gland, 38 (3.3%) had Other Nutritional Deficiencies, 29 (2.5%) had Disorders of other endocrine glands, 7 (0.6%) had other disorders of glucose regulation and pancreatic internal secretion, 5 (0.4%) had Overweight, obesity and other hyperalimentation, 2 (0.2%) had Malnutrition.
Conclusion: Diabetes and Metabolic disorders are the main components of the spectrum of endocrine disorders in admitted cases. Emphasizing the resources essential for further investigation will help both in dealing with and managing the cases of endocrine disorders.
Formation of grammatical forms of full-meaning parts of speech in Ukrainian and Polish languages
Authors: Lesiuk Mykola 
Published: December 2022

The aim of the article is to find out and explain the reasons that differentiate these two grammatical systems and show that common which unites them and gives the basis to consider them closely related. The basis for writing this article served many years of experience in teaching the history of the Ukrainian language compared to other Slavic languages, and the source base, that the author relies on, are the numerous works of Ukrainian and Polish linguists dedicated to the history of Slavic languages.
Basic methods that were used while writing this article – are descriptive and comparative, due to which the author was able to show a great similarity in grammatical forms of main (independent) parts of speech and at the same time differences in these forms caused by these or those reasons that arose in the process of development of languages. In this article those language issues were given, in the process of studying of which the students, who study Polish, had some difficulties. This, in particular, concerns masculine and non-masculine personal forms within the limits of every full-meaning part of speech in Polish, namely here separate forms of masculine were singled out that concern just the males. As for Ukrainian, there isn’t such a variety of declinable forms, that means it went through larger unifications, moreover, if we take the system of verbs (separate verb forms) – under the influence of female samples. Functioning of these grammatical forms is shown in the system of declension of a noun, adjective, pronoun, numeral and a verb.
To conclude, this article will give students and all those who are interested in the language of the nation, namely the representatives of both countries – Ukraine and Poland – the understanding of main grammatical regularities and features of both closely related languages.
Poetic Skovorodiniana of Dnipro region
Authors: Biliatska Valentyna 
Published: December 2022

Research of Hryhorіy Skovoroda phenomenon is significant, but his creative heritage has not been sufficiently studied especially the artistic interpretation of his figure. The poetic image of the Ukrainian philosopher in the lyrics of Dnipro region writers was not the object of scientific study. In the poetry of Dnipro residents Skovoroda is a key figure of our culture, it is a measure of the truth of life values, the personification of the spirit strength, a source of inner harmony and spiritual insight: «gray – haired lubomudr» (S. Burlakov); «judge of earthly vanities», «harsh philosopher», «affectionate judge», «thoughtful» (V. Korzh); «Immortelle-ozonets» (H. Prokopenko).
Assimilating the philosophical and aesthetic experience of Hryhorіy Skovoroda, artistic and ideological aspects of his heritage, the poets of Sicheslav region poetically interpreted the leading philosophical theory of the sage – cognition: by embracing himself and the world around him, a person asserts himself, develops his natural inclinations, chooses his own path and fulfills his earthly purpose; they focused on his teaching about work as a necessity of being to which God called rewarding him with talent and giving him the ability to know himself (S. Burlakov «Slobozhanshchina, I love your gardens», O. Zaivyi «Skovoroda», V. Zemliany «Skovoroda», V. Korzh «From the life of Hryhorіy Skovoroda. Rest», A. Kravchenko-Rusіv «Hryhorіy Skovoroda», N. Nikulina «Over the books of Skovoroda», H. Prokopenko «Testament of Skovoroda», H. Svitlychna «Skovoroda», I. Sokulsky «Skovoroda», K. Chernyshоv «It happens that the spirit of Skovoroda»).
In the poetry of Dnipro region artists symbolic images of Skovoroda are revealed: roads as a fact of the sage’s biography and inner world; garden as a kind of model harmony with nature, God, the world, and with himself, which corresponds to the biblical Garden of Eden and is associated with the immortality of the philosopher and his way of life; hearts and souls as a constant struggle between good and evil, helping to overcome all misconceptions and learn the true essence of a person. The works of poets were written mainly in the 70s and 80s of the twentieth century, but the lyrics interpreted this outstanding personality as a carrier of freedom, a carrier of «free spirit» (K. Chernyshоv), «son of freedom» (H. Prokopenko), and a «freedom-loving person» (A. Zaivyi).
2D magnetotelluric image of the Dobrá Voda seismoactive area
Authors: ONDRÁŠOVÁ Lenka , VOZÁR Ján , HÓK Jozef , CIPCIAR Andrej , GODOVÁ Dominika , KLANICA Radek 
Published: December 2022

Dobrá Voda village is located in the Malé Karpaty Mts. (Brezovské Karpaty) and is well known for its increased seismic activity. For a better understanding of the processes preceding earthquakes, this area has been studied using several methods. One of them is magnetotellurics. Magnetotellurics provides an image of the distribution of electrical conductivity within the Earth and helps to determine individual tectonic structures, specifically faults. The shallow conductive structures are associated with Neogene sediments of the Danube Basin, sedimentary fill of the Dobrá Voda Depression, and partial nappes of Hronicum, probably saturated with water. Less conductive structures are the Fatricum sediments and the lowest conductivity values belong to crystalline basement of the Tatricum tectonic unit. Whole structure of the Dobrá Voda seismoactive area along our magnetotelluric profile is disrupted by NE–SW oriented normal faults. Based on the location of earthquake hypocentres, we can identify main seismoactive areas as crystalline complexes of Tatricum.
PENERAPAN METODE DISCOVERY LEARNING MENURUT TEORI KOGNITIVISME BRUNER DALAM PEMBERIAN LAYANAN BIMBINGAN KONSELING DI SEKOLAH MENENGAH ATAS
Authors: Ayuna Rihya Syifa Qurrotu , Cahyaningrum Agustina , Zakira Shabrina , Baen Suprianto , Tjalla Awaluddin 
Published: December 2022

Tujuan yang dilakukan dalam penelitian ini dalah untuk mengetahui bagaimana guru BK dalam memberikan layanan bk dengan menggunakan metode discovery learning menurut teori Kogitivisme Bruner di SMA Santa Ursula, dan bagaimana layanan guru BK yang diberikan siswa di SMA Santa Ursula. Metode dalam penelitian ini metode Kualitatif dengan pendekatan Deskriptif. Pemilihan subjek penelitian secara purposive sampling. Pengumpulan data dilakukan dengan wawancara, observasi dan dokumentasi. Hasil penelitian membuktikan bahwa berdasarkan teori Kogitivisme Bruner dengan Fase operasi kongkrit, di fase ini siswa di SMA Santa Ursula sudah mampu memecahkan masalah yang sedang dihadapinya secara konkrit. Dari hasil wawancara yang dilakukan dengan guru BK. Sedangkan di Fase operasi formal yaitu pada tahap ini siswa sudah mampu memberikan ide-ide ataupun gagasan yang dimana ide dan gagasan ini diperoleh dari kemampuannya dalam berbahasa dan logika. Dalam memahami dunia sekitarnya siswa menggunakan banyak simbol yaitu dengan cara menggunakan media dalam mendukung keberhasilan kegiatan pembelajarannya. Layanan Guru BK yang sudah diterapkan dengan baik terkait dengan teori kognitivisme Bruner yaitu partisipasi aktif siswa dalam mengenal perbedaan dengan Guru BK sebagai fasilitator, motivator dan evaluator, Penilaian hasil layanan hasil penilaian setelah dilaksanakannya layanan BK yaitu dengan memberikan evaluasi proses dan evaluasi hasil.
Analisa Yuridis Terhadap Pelaku Tindak Pidana Pembunuhan Berencana: Studi Kasus Putusan Nomor 51/Pid.B/2019/PN.Tbh
Authors: Desya Anindyta Rizkyfia , Pratama Hapsari Ifahda , Jaya Wardana Dodi 
Published: December 2022

Artikel ini mengungkap unsur-unsur yang mempengaruhi terjadinya tindak pidana pembunuhan berencana dan pertimbangan hakim dalam kasus Putusan Nomor 51/Pid.B/2019/PN.Tbh. Studi ini menggunakan jenis penelitian hukum normatif yang terdiri dari penelitian terhadap asas-asas hukum, sistematika hukum, sejarah hukum dan penelitian perbandingan hukum. Pendekatan yang digunakan adalah pendekatan undang-undang (Statute Approach), Pendekatan konseptual (Conceptual Approach), dan Pendekatan Kasus (Case Approach). Hasil menunjukan bahwa unsur–unsur tindak pidana pembunuhan berencana yang dilakukan oleh pelaku terbukti memenuhi unsur barangsiapa, unsur menghilangkan orang lain, unsur dengan sengaja, dan unsur direncanakan lebih dahulu. Pertimbangan Majelis Hakim sebelum menjatuhkan putusan Nomor 51/Pid.B/2019/PN.Tbh sudah sesuai dengan aturan hukum yang berlaku dengan mempertimbangkan hal-hal yang memberatkan, dan hal-hal yang meringankan pelaku. Pelaku juga sudah dinyatakan dewasa menurut hukum, dimana pelaku telah berusia dua puluh tahun dan sudah cakap hukum.
Peran Pemkab Magelang Dalam Pelaksanaan Pemajuan Kebudayaan Tari Topeng Ireng
Authors: Sintha Dewi Dyah Adriantini , Anggraini Vivin , Sulistyaningsih Puji 
Published: December 2022

Pemberian perlindungan bagi ekspresi budaya tradisional menjadi penting ketika dihadapkan pada karakteristik dan keunikan yang dimilikinya dan juga berperan positif memberikan dukungan kepada komunitas masyarakat hukum adat selaku pemilik dan pengemban kebudayaan tersebut untuk melestarikan tradisinya. Agar kepemilikannya tidak diakui tanpa izin oleh negara lain.
Oleh sebab itu, kekayaan budaya tersebut perlu memperoleh perlindungan hukum. Di Kabupaten Magelang terdapat kesenian tari tradisional topeng ireng, perkembangan seni Topeng Ireng saat ini sangat beragam, mulai dari lagu hingga irama dan kostumnya. Sebagai upaya untuk melindungi dan memajukan kesenian tradisional topeng ireng di Kabupaten Magelang maka diperlukan upaya dan peran dari pemerintah daerah Kabupaten Magelang. Untuk diperlukan suatu strategi dalam pengambilan kebijakan yang dilakukan.

Pendekatan yang digunakan dalam penelitian ini, yaitu pendekatan undang-undang (statue approach) dan pendekatan penelitian field research (lapangan). Jenis penelitian yang digunakan penelitian ini adalah pendekatan yuridis sosiologis. Sumber data diambil secara primer yaitu melalui wawancara, bahan hukum primer yang digunakan yaitu Undang-Undang Nomor 28 Tahun 2014 tentang Hak Cipta, Undang-Undang Nomor 5 Tahun 2017 tentang Pemajuan Kebudayaan.
Dinas Pendidikan dan Kebudayaan Kabupaten Magelang dalam upaya memajukan kebudayaan seni tari topeng ireng belum berjalan dengan baik. Dalam upaya pemajuan kebudayaan seni tari topeng ireng di Kabupaten Magelang, pemerintah khususnya Dinas Pendidikan dan Kebudayan belum melakukan publikasi kebudayaan dan kesenian di Kabupaten Magelang yang sudah disahkan. Sehingga dalam hal ini Pemerintah Kabupaten Magelang seharusnya dapat segera memperbaiki hal tersebut dengan membuatkan sebuah media publikasi baik itu website, instagram maupun media sosial online lainnya.
Pemerintah Kabupaten Magelang khususnya Dinas Pendidikan dan Kebudayaan Kabupaten Magelang yang bertanggung jawab akan pendataan kesenian Tari Topeng Ireng ini, sebagaimana pada Pasal 15 Ayat (1) Undang-Undang Pemajuan Kebudayaan yang menyatakan bahwa Sistem Pendataan Kebudayaan Terpadu dibentuk oleh Menteri. Sebagaimana dalam Pasal 1 Angka 17 Undang-Undang Pemajuan Kebudayaan menyebutkan bahwa Menteri yang dimaksud dalam Undang-Undang ini adalah menteri yang menyelenggarakan urusan pemerintahan di bidang kebudayaan.
Pertanggungjawaban Pidana Pelaku Jual Beli Anjing Tanpa Sertifikat Veteriner (Studi Putusan Nomor 99/Pid.Sus/2021/PN Wat)
Authors: Wardhana Ega Kusuma , Kurniaty Yulia , Krisnan Jhony , Basri Basri 
Published: December 2022

Dari hasil investigasi yang dilakukan JAAN (Jakarta Animal Aid Network) terdapat suatu perdagangan daging konsumsi yang menggunakan daging anjing. Terdapat 500 ekor anjing tiap harinya yang masuk ke Surakarta, dengan cara masuk tanpa adanya pengawasa, sertifikat, dan juga adanya proses karantina. Tujuan penulisan ini untuk menganalisa sanksi pidana dan pertanggungjawaban pidana pelaku penyelundupan anjing dari daerah tertular atau terduga tertular rabies ke wilayah bebas penyakit rabies serta untuk mengetahui pertimbangan hakim dalam memutus kasus tersebut.
Metode penulisan yang digunakan dalam penelitian ini menggunakan metode pendekatan undang-undang dan juga kasus, jenis penelitian yang digunakan adalah hukum normatif, spesifikasi penelitian yang digunakan adalah deskriptif analitis, sumber hukum yang digunakan meliputi sumber hukum primer dan sumber hukum sekunder. Pendekatan penelitian data menggunakan analisis deskriptif kualitatif. Hasil penelitian ini berupa pertanggungjawaban pidana bagi pelaku tindak pidana memasukan hewan anjing yang tidak dilengkapi dokumen SKKH dari daerah tertular atau terduga tertular penyakit rabies ke wilayah bebas penyakit rabies di Indonesia diatur dalam UU RI No. 41 Tahun 2014 atas perubahan UU RI No. 18 Tahun 2009 tentang Peternakan.dan Kesehatan.Hewan, dimana saknsi pidananya terdapat pada Pasal 89 ayat (2) juncto pasal 46 ayat (5) UU tersebut. Dalam kasus pada Putusan Nomor 99/Pid.Sus/2021/PN Wat menurut peneliti ada hal yang mustinya dapat menjadi bahan pertimbangan hakim dalam memperberat putusan terhadap terdakwa dimana dalam fakta persidangan terungkap perbuatan terdakwa dilakukan lebih dari satu kali yang menurut peneliti seharusnya dapat dijadikan pertimbangan yang memberatkan oleh hakim dalam memutus perkara tersebut mengingat peredaran/jual beli anjing tanpa adanya sertifikat veternier atau ijin pengawasan sangat membahayakan bagi masyarakat khususnya dari segi kesehatan.