bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of pesticide regulations on mortality from suicide by pesticide in China: an interrupted time series analysis
Authors: Yan Yongfu , Jiang Yingying , Liu Rong , Eddleston Michael , Tao Chuanjiang , Page Andrew , Wang Lijun , Feng Guoshuang , Liu Shiwei 
Published: September 2023

BackgroundPesticide bans and regulatory restrictions have been shown to be effective strategies for preventing suicide in several countries. Suicide and suicide by pesticides have decreased significantly in China over the past two decades. However, whether the reduction was associated with pesticide regulation is unknown.MethodsThe monthly data on suicide and suicide by pesticide from 2006 to 2018 were obtained from China's Disease Surveillance Point (DSP) system. Information on China's pesticide regulations since 1970 was obtained from Pesticide Action Network International (PAN International), Joint Meeting on Pesticide Management Highly Hazardous Pesticides (JMPM HHP) lists, the website of the Ministry of Agriculture of China, Pesticide Information Network of China, and the Wan Fang database. Change point detection and policy analysis were combined to identify the time of any trend change breakpoint of suicide and suicide by pesticide. Interrupted time series analysis was used to investigate the pre- and post-breakpoint trends of monthly standardized rates in suicide and suicide by pesticide.ResultsThe standardized pesticide suicide rate decreased by 60.5% from 6.50 in 2006 to 2.56 per 100,000 in 2018. Larger declines were evident among people in urban areas (67.3%), female individuals (63.5%), and people aged 15–44 years (68.1%). The effect of policies banning highly hazardous organophosphorus pesticides (HHOP) [rate ratio (RR) = 0.993, 95% CIs (0.991–0.994)] in December 2008 and stopping domestic sales and use of paraquat aqueous solution (RR = 0.992, 95% CIs: 0.990–0.994) in July 2016 were more pronounced than regulating the paraquat-related products (RR = 1.003, 95% CIs: 1.002–1.004) in April 2012.ConclusionDeclines in suicide by pesticide in China occurred contemporaneously with regulatory bans and restrictions implemented on several pesticides, particularly in urban areas, among female individuals, and the relatively low age profile. These findings indicate the potential influence of these bans on trends of suicide by pesticides.
Racial differences in pathways to care preceding first episode mania or psychosis: a historical cohort prodromal study
Authors: Gardea-Resendez Manuel , Ortiz-Orendain Javier , Miola Alessandro , Fuentes Salgado Manuel , Ercis Mete , Coombes Brandon J. , Gruhlke Peggy M. , Bostwick J. Michael , Michel Ian , Vande Voort Jennifer L. , Ozerdem Aysegul , McKean Alastair , Frye Mark A. , Taylor-Desir Monica 
Published: September 2023

BackgroundThere is evidence suggesting racial disparities in diagnosis and treatment in bipolar disorder (BD) and schizophrenia (SZ). The purpose of this study is to compare psychiatric diagnoses and psychotropic use preceding a first episode of mania (FEM) or psychosis (FEP) in racially diverse patients.MethodsUsing a comprehensive medical records linkage system (Rochester Epidemiology Project, REP), we retrospectively identified individuals diagnosed with BD or SZ and a documented first episode of mania or psychosis. Illness trajectory before FEP/FEM were characterized as the time from first visit for a mental health complaint to incident case. Pathways to care and clinical events preceding FEP/FEM were compared based on subsequent incident case diagnosis (BD or SZ) and self-reported race (White vs. non-White).ResultsA total of 205 (FEM = 74; FEP = 131) incident cases were identified in the REP. Duration of psychiatric antecedents was significantly shorter in non-White patients, compared to White patients (2.2 ± 4.3 vs. 7.4 ± 6.6 years; p &lt; 0.001) with an older age at time of first visit for a mental health complaint (15.7 ± 6.3 vs. 11.1 ± 6.0 years; p = 0.005). There were no significant differences by race in FEM pathway to care or age of first seeking mental health. Overall non-White patients had lower rates of psychotropic use.ConclusionThese data are unable to ascertain reasons for shorter duration of psychiatric antecedents and later age of seeking care, and more broadly first age of initial symptom presentation. If symptoms are confirmed to be earlier than first time seeking care in both groups, it would be important to identify barriers that racial minorities face to access timely psychiatric care and optimize early intervention strategies.
Patterns of pediatric and adolescent female genital inflammation in China: an eight-year retrospective study of 49,175 patients in China
Authors: Gao Huihui , Zhang Yuchen , Pan Yanzheng , Zhao Mengjia , Qi Ye , Zhou Mingming , Chan Symphorosa S. C. , Huang Siyi , Song Peige , Tang Kun , Sun Liying , Yuan Changzheng 
Published: September 2023

BackgroundGenital inflammation is one of the most frequent clinical complaints among girls, which was easily overlooked by the general public. This study aimed to investigate the patterns and epidemiological characteristics of pediatric and adolescent female genital inflammation in China.MethodsA retrospective observational study (2011 to 2018) was conducted among all female patients under the age of 0–18 years at the Department of Pediatric and Adolescent Gynecology of The Children’s Hospital, Zhejiang University School of Medicine. Data were collected from the electronic medical records. The abnormal vaginal discharge of patient was collected for microbiological investigation by bacterial and fungal culture. Descriptive analysis was conducted to evaluate the genital inflammation pattern and epidemiological characteristics, including age, season, and type of infected pathogens.ResultsA total of 49,175 patients met the eligibility criteria of genital inflammation and 16,320 patients later came to the hospital for follow-up over the study period. The number of first-visit increased gradually from 3,769 in 2011 to 10,155 in 2018. The peak age of the first visit was 0–6 years old. Non-specific vulvovaginitis, lichen sclerosis, and labial adhesion were the top three genital inflammation. Among the top five potential common pathogens of vaginal infection, the prevalence of Haemophilus influenzae cases was the highest (31.42%, 203/646), followed by Streptococcus pyogenes (27.74%, 176/646), Candida albicans (14.09%, 91/646), Escherichia coli (8.51%, 55/646), and Staphylococcus aureus (6.35%, 41/636). The specific disease categories and pathogens of genital inflammation vary by age groups and season.ConclusionOur study summarizes the pattern of pediatric and adolescent female genital inflammation over an 8-year period in China, emphasizing the need for more public awareness, healthcare services and research in this field.
Illness representation of COVID-19 affected public’s support and anticipated panic regarding the living with the virus policy: a cross-sectional study in a Chinese general population
Authors: Yu Yanqiu , Ling Rachel Hau Yin , Ng Joyce Hoi-Yuk , Lau Mason M. C. , Ip Tsun Kwan Mary , Lau Joseph T. F. 
Published: September 2023

BackgroundThere is a global trend for countries to adopt the Living with the Virus (LWV) policy regarding COVID-19. Little is known about the public’s supportiveness and emotional responses (e.g., anticipated panic) related to this policy. Such responses may be associated with illness representations of COVID-19 (i.e., how people think and feel about COVID-19). This novel topic was investigated in this study to facilitate policy-making and health communication.MethodsA random, population-based telephone survey interviewed 500 adults aged ≥18 of the Hong Kong general adult population from March to April 2022.ResultsThe prevalence of the public’s support and anticipated panic regarding the LWV policy, which were negatively correlated with each other, was 39.6 and 24.2%, respectively. The illness representation constructs of consequences, timeline, identity, illness concern, and emotional representations were negatively associated with supportiveness and positively associated with anticipated panic regarding the LWV policy. Illness coherence was significantly associated with policy support but not with anticipated panic. The associations between personal control/treatment control and supportiveness/anticipated panic were statistically non-significant. Moderation analyses showed that the above significant associations were invariant between those with and without previous COVID-19 infection.ConclusionPolicymakers need to be sensitized about the public’s supportive/unsupportive attitude and potential worry (panic) when adopting the LWV policy. Such attitudes/emotional responses may be affected by people’s illness representations of COVID-19. In general, those who found COVID-19 involving a milder nature and less negative emotions would be more supportive and anticipated less panic under the LWV policy.
Excessive whole-body exposure to 28 GHz quasi-millimeter wave induces thermoregulation accompanied by a change in skin blood flow proportion in rats
Authors: Ijima Etsuko , Kodera Sachiko , Hirata Akimasa , Hikage Takashi , Matsumoto Akiko , Ishitake Tatsuya , Masuda Hiroshi 
Published: September 2023

IntroductionLimited information is available on the biological effects of whole-body exposure to quasi-millimeter waves (qMMW). The aim of the present study was to determine the intensity of exposure to increase body temperature and investigate whether thermoregulation, including changes in skin blood flow, is induced in rats under whole-body exposure to qMMW.MethodsThe backs of conscious rats were extensively exposed to 28 GHz qMMW at absorbed power densities of 0, 122, and 237 W/m2 for 40 minutes. Temperature changes in three regions (dorsal and tail skin, and rectum) and blood flow in the dorsal and tail skin were measured simultaneously using fiber-optic probes.ResultsIntensity-dependent temperature increases were observed in the dorsal skin and the rectum. In addition, skin blood flow was altered in the tail but not in the dorsum, accompanied by an increase in rectal temperature and resulting in an increase in tail skin temperature.DiscussionThese findings suggest that whole-body exposure to qMMW drives thermoregulation to transport and dissipate heat generated on the exposed body surface. Despite the large differences in size and physiology between humans and rats, our findings may be helpful for discussing the operational health-effect thresholds in the standardization of international exposure guidelines.
Interpreting match performance in elite futsal: considerations for normalizing variables using effective time
Authors: Spyrou Konstantinos , Ribeiro João Nuno , Ferraz António , Alcaraz Pedro E. , Freitas Tomás T. , Travassos Bruno 
Published: September 2023

IntroductionThis study aimed to investigate the physical and individual technical-tactical performance of elite futsal players.MethodsThirteen National Team futsal players (27.4 ± 4.7 years, 70.3 ± 7.6 kg, 176.3 ± 5.5 cm) competed in 15 official matches in three distinct competitions. Session rate of perceived exertion (sRPE) and player load (PL) were measured for assessing physical internal and external load, respectively. Individual tactical actions were analyzed using Instat Scout®, considering variables such as fouls, shots, shots on target, goals, successful dribbles, passes, successful passes, ball losses, ball recoveries, and challenges won.ResultsThe cluster analysis classified the players into two groups: “high-involvement” (HIGH) and “low-involvement” (LOW), based on their average effective playing time, sRPE, and PL. A linear mixed model was used to examine the differences in external and internal load and technical-tactical variables between the two groups, accounting for individual repeated measures. Considering absolute values, HIGH players presented higher sRPE, RPE, total PL, shots, goals, passes, successful passes, ball losses and recoveries, and challenges won (p = 0.001–0.039; ES = 0.43–2.48), when compared to their LOW counterparts. However, when analyzed relative to effective time, LOW players reached higher total PL and shots per minute (p = 0.001–0.012; ES = 0.39–0.93) when compared to HIGH players. Non-significant differences were found for the rest of the variables.DiscussionIn summary, these results emphasize the importance of normalizing internal and external load variables and technical-tactical performance variables per effective playing time in futsal. The current findings indicate that players with lower involvement can present the same or even higher physical and technical-tactical performance compared to teammates with more playing time.
Challenging structures: gender transformative interventions by livestock CRP in Ethiopia
Authors: Kinati Wole , Temple Elizabeth C. , Baker Derek , Najjar Dina 
Published: September 2023

IntroductionThis study is a review of secondary literature that has been synthesized to extract information and demonstrate the implementation and impact of community conversations (CCs) on gender aspects of social norms in livestock-based systems in Ethiopia.MethodsThe study used the phenomenological method of qualitative literature review to sketch the gender transformative approach to the delivery of knowledge products in a program on transforming the small ruminant value chain. The CC aimed at addressing gender-related norms in the division of labor, resource ownership, and handling practices of animals and their products previously identified, and those that emerged during the CC events across the study sites. A total of 1,517 community members (out of which 574 are women) took part in various CC events.Results and discussionThe review shows that the gender-related norms addressed were in line with the identified constraining norms faced by women livestock keepers in the mixed and livestock-based systems. The CC approach adopted complied with the stages laid out in literature: identification of existing knowledge; imparting new knowledge; knowledge integration and application; and review, reflection, and re-planning. The process was inclusive and community-engaging, which possibly cultivated intrinsic motivation and ownership of the process. Changes in knowledge, attitudes, and practices at household, community, and institutional levels were identified. The conclusions include institutionalizing the gender transformative approach in the public agricultural extension system. This could be facilitated by the generation of robust objective evidence of impacts and guidance for subsequent scaling at local, regional, and national levels.
Accuracy of the Personal Economic Distress Index Among Arabic Unemployed
Authors: Razki Khouloud , Zgueb Yosra , Aissa Amina , Ouali Emna Sofia , Wahabi Anis , Ouali Uta 
Published: September 2023

Objectives: Studies about The Index of Personal Economic Distress (IPED) in Arab countries since the onset of the COVID-19 pandemic have been alarming. This study aimed to explore the reliability, factor structure, and criterion validity of the Arabic IPED in a sample of unemployed Tunisians during the past 6 months.Methods: The Arabic version of the IPED and the validated Hospital Anxiety and Depression Scale (HADS) were administered to a total of 2011 unemployed people originating from all Tunisian regions. Principal component analysis (PCA) with confirmatory factor analysis (CFA) was used to establish the spontaneous distribution of the 8 items and possible factors of the IPED. Receiver operating characteristic (ROC) analysis was conducted to assess the ability of the IPED to distinguish between unemployed individuals with no economic distress and those in distress. The correlation between the IPED and the HADS were explored.Results: The reliability of the Arabic version of the IPED was adequate. The PCA suggested two main components of the Arabic version of the IPED: the first component including five items focused on financial responsibilities towards state structures and the second dimension containing three items focused on well-being. A statistically significant association (p = 0.01; r = 0.05) was found between the well-being dimension of the IPED and the Anxiety subscale of HADS.Conclusion: This validated version of the IPED is an important tool to study the impact of economic crises on the mental health of unemployed people, as demonstrated in the link found in this study between economic distress and anxiety.
The Effect of Continuous Liver Normothermic Machine Perfusion on the Severity of Histological Bile Duct Injury
Authors: Gilbo Nicholas , Neil Desley , Brais Rebecca , Fieuws Steffen , Lo Faro Letizia , Friend Peter , Ploeg Rutger , Monbaliu Diethard 
Published: September 2023

Static Cold Storage (SCS) injures the bile duct, while the effect of Normothermic Machine Perfusion (NMP) is unknown. In a sub-study of the COPE trial on liver NMP, we investigated the impact of preservation type on histological bile duct injury score (BDIS). Transplants with at least one bile duct biopsy, either at end of preservation or 1 h post-reperfusion, were considered. BDIS was determined by assessing peribiliary glands injury, stromal and mural loss, haemorrhage, and thrombosis. A bivariate linear model compared BDIS (estimate, CI) between groups. Sixty-five transplants and 85 biopsies were analysed. Twenty-three grafts were preserved with SCS and 42 with NMP, with comparable baseline characteristics except for a shorter cold ischemic time in NMP. The BDIS increased over time regardless of preservation type (p = 0.04). The BDIS estimate was higher in NMP [8.02 (7.40–8.65)] than in SCS [5.39 (4.52–6.26), p &lt; 0.0001] regardless of time. One patient in each group developed ischemic cholangiopathy, with a BDIS of 6 for the NMP-preserved liver. In six other NMP grafts, BDIS ranged 7–12 without development of ischemic cholangiopathy. In conclusion, BDIS increases over time, and the higher BDIS in NMP did not increase ischemic cholangiopathy. Thus, BDIS may overestimate this risk after liver NMP.
Asymptotically Optimal Adversarial Strategies for the Probability Estimation Framework
Authors: Patra Soumyadip , Bierhorst Peter 
Published: September 2023

The probability estimation framework involves direct estimation of the probability of occurrences of outcomes conditioned on measurement settings and side information. It is a powerful tool for certifying randomness in quantum nonlocality experiments. In this paper, we present a self-contained proof of the asymptotic optimality of the method. Our approach refines earlier results to allow a better characterisation of optimal adversarial attacks on the protocol. We apply these results to the (2,2,2) Bell scenario, obtaining an analytic characterisation of the optimal adversarial attacks bound by no-signalling principles, while also demonstrating the asymptotic robustness of the PEF method to deviations from expected experimental behaviour. We also study extensions of the analysis to quantum-limited adversaries in the (2,2,2) Bell scenario and no-signalling adversaries in higher (n,m,k) Bell scenarios.
Improvements of Age-Related Cognitive Decline in Mice by Lactobacillus helveticus WHH1889, a Novel Strain with Psychobiotic Properties
Authors: Gao Kan , Chen Cailing , Ke Xueqin , Fan Qiuling , Wang Haifeng , Li Yanjun , Chen Su 
Published: September 2023

A gradual decline in cognitive function occurs with age. Accumulating evidence suggests that certain probiotic strains exert beneficial effects on age-related cognitive decline. Our previous study revealed that Lactobacillus helveticus WHH1889 attenuated symptoms of anxiety and depression in depressed mice via shaping the 5-hydroxytryptamine (5-HT) and 5-hydroxytryptophan (5-HTP) metabolism and gut microbial community, indicating the psychobiotic potential of WHH1889. In the present study, the effects of WHH1889 on age-related cognitive decline were investigated. WHH1889 was orally administrated (1 × 109 CFU/day) for twelve weeks in aged mice, and their cognitive behaviors, neurochemical factors, cognitive-related gene expressions, neuroinflammation, and serum tryptophan pathway-targeted metabolic profiling, as well as gut microbiome composition were assessed. WHH1889 demonstrated improvement of the cognitive behaviors via the novel object recognition test (NORT), the active shuttle avoidance test (ASAT), the Y-maze test, and the passive avoidance test (PAT). The hippocampal neuronal loss; the declined concentrations of BDNF, 5-HT, and 5-HTP; the decreased gene expressions of neurodegeneration biomarkers; and the increased production of hippocampal inflammatory cytokines in aged mice were restored by WHH1889. In addition, WHH1889 increased the 5-HT/5HTP levels and decreased the serum levels of tryptophan-derived metabolites (e.g., kynurenine, xanthurenic acid, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid). Furthermore, WHH1889 was revealed to shape the gut microbiota community by reversing the relative abundances of Bacteroidota and Firmicutes. The present findings suggest that L. helveticus WHH1889 exerted cognitive improving effects on aged mice, which was associated with the modulation of 5-HT and 5-HTP metabolism and gut microbial composition. The supplementation of WHH1889 may therefore be a promising therapeutic agent for age-related cognitive deficits.
Jouer (et donner) à penser. Une lecture de Roberte Hamayon en contexte(s) chinois
Authors: Vermander Benoît 
Published: September 2023

Jouer, de Roberte Hamayon, apporte un éclairage spécifique sur les mécanismes régissant tout un pan des interactions sociales, dans le monde asiatique et au-delà. Pour en souligner la fécondité, cet article procède en quatre temps. En l’abordant sous l’angle d’une « économie morale du jeu », il le rapproche et le contraste tout à la fois de l’Essai sur le don, de Marcel Mauss ; il illustre le mode d’articulation entre rite et jeu suggéré par la lecture croisée de ces deux ouvrages au travers d’une description des enjeux attachés à la célébration des rituels chez les Nuosu (Yi de Liangshan), dans le sud-ouest du Sichuan. Dans un deuxième temps, l’article continue à explorer les effets sociaux produits par le croisement de l’action rituelle, du jeu et du don en relisant les analyses de R. Hamayon à la lumière de Marcel Granet. La troisième partie contraste l’unité sémantique du champ considéré dans l’aire culturelle étudiée par R. Hamayon avec l’éclatement (au moins apparent) du vocabulaire du « jouer » en monde chinois ; et elle signale certaines pratiques récentes qui résonnent avec les intuitions développées dans l’ouvrage. La dernière partie s’appuie sur les Recherches philosophiques de Ludwig Wittgenstein pour esquisser quelques réflexions autour de l’articulation entre « jeu », « langage » et « pensée ».
Un nuevo pedúnculo de Memoria, Verdad y Justicia. Dos narraciones orales sobre el colectivo Historias Desobedientes
Authors: Médica Gerardo 
Published: September 2023

En mayo de 2017, luego del controvertido fallo de la Corte Suprema de Justicia comúnmente llamado “2x1” y su intento de aplicación a responsables de crímenes de lesa humanidad en el país, comienza a constituirse haciendo su primera aparición pública en la Marcha “Ni una Menos”, el colectivo Historias Desobedientes (Hijos, Hijas y Familiares de Genocidas por la Memoria, Verdad y Justicia). Dicho colectivo se ha ubicado en el escenario de luchas por los derechos humanos del país como una agrupación política-social en defensa de las políticas de Memoria, Verdad y Justicia.
El presente trabajo centrado en las “historias de vida” y los relatos orales de Analía Kalinec y Bibiana Reibaldi (integrantes fundacionales del colectivo) busca explorar el tránsito individual y colectivo que las posicionó como militantes por la Memoria, Verdad y Justicia rompiendo los mandatos familiares de negación y silencio.