bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examples of non-Dini domains with large singular sets
Authors: Kenig Carlos , Zhao Zihui 
Published: April 2023

Abstract
Let

u

u

be a nontrivial harmonic function in a domain

D
⊂

R

d

D\subset {{\mathbb{R}}}^{d}

, which vanishes on an open set of the boundary. In a recent article, we showed that if

D

D

is a

C

1

{C}^{1}

-Dini domain, then, within the open set, the singular set of

u

u

, defined as

{

X
∈

D

¯

:
u

(

X

)

=
0
=
∣

∇

u

(

X

)

∣

}

\left\{X\in \overline{D}:u\left(X)=0=| \nabla u\left(X)| \right\}

, has finite

(

d
−
2

)

\left(d-2)

-dimensional Hausdorff measure. In this article, we show that the assumption of

C

1

{C}^{1}

-Dini domains is sharp, by constructing a large class of non-Dini (but almost Dini) domains whose singular sets have infinite

ℋ

d
−
2

{{\mathcal{ {\mathcal H} }}}^{d-2}

-measures.
Meta-analysis of the rs231775 locus polymorphism in the CTLA-4 gene and the susceptibility to Graves’ disease in children
Authors: Shi Mili , Liu Xiaobo , Song Qiuyan , Shi Yijie , Tai Qirui 
Published: April 2023

Abstract
The aim of this study was to systematically evaluate the correlation between the rs231775 locus polymorphism in the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene and genetic susceptibility to Graves’ disease (GD) in children. Some studies found that the CTLA-4 gene polymorphism was associated with GD in children. The data up to February 2022 were retrieved from the databases. Stata 15.0 software was used for meta-analysis. A total of seven studies were included in our research. The results of the meta-analysis showed that the rs231775 locus polymorphism in the CTLA-4 gene in general and Asian populations was correlated with children’s susceptibility to GD (A vs G: OR = 0.75, 95% CI (0.660–0.86); GG vs AA: OR = 1.34, 95% CI (1.04–1.73); AG vs AA: OR = 1.32, 95% CI (1.02–1.10); AG + GG vs AA: OR = 3.81, 95% CI (2.17–6.70); GG vs AA + AG: OR = 1.23, 95% CI (1.05–1.45)). In summary, the rs231775 locus polymorphism in the CLTA-4 gene may be a risk factor for GD in Asian children. The G allele may be a susceptibility factor, while the allele A may be a protective factor against GD in Asian children. In the future, more large-scale studies may be needed to verify our results.
Parameter-based patient-specific restoration of physiological knee morphology for optimized implant design and matching
Authors: Grothues Sonja , Becker Ann-Kristin , Hohlmann Benjamin , Radermacher Klaus 
Published: April 2023

Abstract
Total knee arthroplasty (TKA) patients may present with genetic deformities, such as trochlear dysplasia, or deformities related to osteoarthritis. This pathologic morphology should be corrected by TKA to compensate for related functional deficiencies. Hence, a reconstruction of an equivalent physiological knee morphology would be favorable for detailed preoperative planning and the patient-specific implant selection or design process. A parametric database of 673 knees, each described by 36 femoral parameter values, was used. Each knee was classified as pathological or physiological based on cut-off values from literature. A clinical and a mathematical classification approach were developed to distinguish between affected and unaffected parameters. Three different prediction methods were used for the restoration of physiological parameter values: regression, nearest neighbor search and artificial neural networks. Several variants of the respective prediction model were considered, such as different network architectures. Regarding all methods, the model variant chosen resulted in a prediction error below the parameters’ standard deviation, while the regression yielded the lowest errors. Future analyses should consider other deformities, also of tibia and patella. Furthermore, the functional consequences of the parameter changes should be analyzed.
Interactions of Na+/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy
Authors: Zakrzewicz Dariusz , Geyer Joachim 
Published: April 2023

Abstract
Na+/taurocholate cotransporting polypeptide (NTCP) is a member of the solute carrier (SLC) family 10 transporters (gene symbol SLC10A1) and is responsible for the sodium-dependent uptake of bile salts across the basolateral membrane of hepatocytes. In addition to its primary transporter function, NTCP is the high-affinity hepatic receptor for hepatitis B (HBV) and hepatitis D (HDV) viruses and, therefore, is a prerequisite for HBV/HDV virus entry into hepatocytes. The inhibition of HBV/HDV binding to NTCP and internalization of the virus/NTCP receptor complex has become a major concept in the development of new antiviral drugs called HBV/HDV entry inhibitors. Hence, NTCP has emerged as a promising target for therapeutic interventions against HBV/HDV infections in the last decade. In this review, recent findings on protein–protein interactions (PPIs) between NTCP and cofactors relevant for entry of the virus/NTCP receptor complex are summarized. In addition, strategies aiming to block PPIs with NTCP to dampen virus tropism and HBV/HDV infection rates are discussed. Finally, this article suggests novel directions for future investigations evaluating the functional contribution of NTCP-mediated PPIs in the development and progression of HBV/HDV infection and subsequent chronic liver disorders.
Investigating willingness to communicate vis-à-vis learner talk in a low-proficiency EAP classroom in the UK study-abroad context
Authors: Zhou Qianqian 
Published: April 2023

Abstract
A large body of research has investigated the factors which underlie willingness to communicate (WTC). However, scant scholarly attention has been paid to WTC vis-à-vis learner talk, i.e., how intentions to talk translates into talk. Drawing on Dörnyei’s retrodictive qualitative modelling template, this research comprises a qualitative multiple-case study of three South Korean students who were learning English in a low-proficiency EAP classroom in the UK study-abroad context. Specifically, the study examined what factors facilitated or hindered their WTC-talk realisation. Methodological triangulation was achieved by means of classroom observations, audio-stimulated recall interviews and semi-structured interviews. Findings revealed five individual factors and four contextual factors which formed various interactional patterns and interdependently influenced the three students’ WTC-talk realisation. Such interactional patterns showcase how individual and contextual factors interact and contribute to WTC and individual differences in communication frequency in the EAP classroom. The study provides novel empirical evidence for the influence of the Korean Confucian-based culture of learning and communication on students’ L2 practice. Informed by the complex dynamic systems theory, the study concludes with pedagogical implications that aim to inspire EAP practitioners to cultivate WTC-friendly classes that optimise the realisation of learner talk.
Computational analysis of nuclear desalination system under various configurations
Authors: Ud-Din Khan Salah , Orfi Jamel 
Published: April 2023

Abstract
The research addressed the economic evaluation of nuclear energy, coal, oil and natural gas in various cycle configurations with different distillation technologies. A comparison between fossil and nuclear energy sources is discussed. A comprehensive review of all desalination plants using fossil and nuclear energy with cogeneration is also included and discussed. Computational model was used to evaluate nuclear and non-nuclear desalination plants. Four possibilities were discussed. In this first case, a nuclear gas cycle integrated with a MED desalination plant was found to have the lowest cost in the gas cycle. While the nuclear steam cycle integrated with RO has the lowest cost compared to oil and natural gas. In the third case, the combined nuclear cycle was discussed and it was found that the combined nuclear cycle associated with RO has the lowest cost. In the last case, the evaluation of a heat-only desalination plant was conducted among all sources, and it was found that the nuclear plant with RO and MED has the lowest cost. In addition, the completed nuclear desalination plant was subjected to five scenarios to calculate and estimate at which capacity the plant provides the best values. The results show that nuclear desalination with gas cycle is the most economical among the oil and natural gas options.
A self-adaptive inertial extragradient method for a class of split pseudomonotone variational inequality problems
Authors: Owolabi Abd-Semii Oluwatosin-Enitan , Alakoya Timilehin Opeyemi , Mewomo Oluwatosin Temitope 
Published: April 2023

Abstract
In this article, we study a class of pseudomonotone split variational inequality problems (VIPs) with non-Lipschitz operator. We propose a new inertial extragradient method with self-adaptive step sizes for finding the solution to the aforementioned problem in the framework of Hilbert spaces. Moreover, we prove a strong convergence result for the proposed algorithm without prior knowledge of the operator norm and under mild conditions on the control parameters. The main advantages of our algorithm are: the strong convergence result obtained without prior knowledge of the operator norm and without the Lipschitz continuity condition often assumed by authors; the minimized number of projections per iteration compared to related results in the literature; the inertial technique employed, which speeds up the rate of convergence; and unlike several of the existing results in the literature on VIPs with non-Lipschitz operators, our method does not require any linesearch technique for its implementation. Finally, we present several numerical examples to illustrate the usefulness and applicability of our algorithm.
Cd(II) and As(V) removal from the multicomponent solutions in the presence of ionic polymers using carbonaceous adsorbents obtained from herbs
Authors: Gęca Marlena , Wiśniewska Małgorzata , Nowicki Piotr , Jędruchniewicz Katarzyna 
Published: April 2023

Abstract
Biochars and activated carbons obtained from the nettle and the sage herbs were used for Cd(II), As(V), poly(acrylic acid) and polyethylenimine simultaneous adsorption from the multicomponent aqueous solutions. Electrokinetic studies proved that both activated carbons show acidic character of the surface. The point of zero charge of the sample obtained from the nettle herb occurs at pH 3.1, whereas that of the adsorbent obtained from the sage herb at pH 4.0. Cd(II) adsorption causes the decrease in the surface charge density and the zeta potential of both activated carbons, whereas As(V) addition results in the increase of solid surface charge density and its impact on the zeta potential value depends on adsorbent type. In case of the simultaneous presence of metals and polymers, the adsorbed macromolecules have greater influence on the surface charge density and the zeta potential values than the metal ions. Cd(II) and As(V) are well adsorbed on the examined activated carbons irrespective of the solution pH (changing in the range 3–9). Maximum adsorption were 218.27 mg/g for Cd(II) and 205.53 mg/g for As(V). The polymers presence causes a decrease (80–90 %) of both metal ions adsorbed amounts, whereas the poly(acrylic acid) and polyethylenimine adsorption mechanism in the presence of cadmium and arsenic ions depends on the adsorbent type and polymer-metal interactions.
Correlation between PSOGI pathological classification and survival outcomes of patients with pseudomyxoma peritonei treated using cytoreductive surgery and HIPEC: national referral centre experience and literature review
Authors: Martín-Román Lorena , Hannan Enda , Faraz Khan Mohammad , Müller Anna Sophia , Shields Conor , Aird John , Moran Brendan , Mulsow Jurgen 
Published: April 2023

Abstract

Objectives
The Peritoneal Surface Oncology Group International (PSOGI) consensus subdivided pseudomyxoma peritonei (PMP) into four groups according to histopathological features. The aim of this paper is to report survival outcomes after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) from a national referral centre and to correlate the PSOGI classification with survival.

Methods
A retrospective study of a prospectively maintained database was performed. Consecutive patients treated with CRS + HIPEC for PMP of appendiceal origin were included (September-2013 to December-2021). Pathological features of the peritoneal disease were used to classify patients into the four groups proposed by PSOGI. Survival analysis was performed to evaluate the correlation of pathology on overall survival (OS) and disease-free survival (DFS).

Results
Overall, 104 patients were identified; 29.6 % were reclassified as acellular mucin (AM), 43.9 % as low-grade mucinous carcinoma peritonei (LGMCP), 22.4 % as high-grade MCP (HGMCP) and 4.1 % as HGMCP with signet ring cells (HGMCP-SRC). Median PCI and rate of optimal cytoreduction were 19 and 82.7 %, respectively. Median OS and DFS were not reached, 5-year OS and DFS were 88.6(SD 0.04) % and 61.6(SD 0.06) %, respectively. Log-Rank test revealed significant differences in terms of OS and DFS across the different histological subgroups (p<0.001 in both cases). However, histology did not retain its significance in the multivariate analysis for OS or DFS (p=0.932 and p=0.872, respectively).

Conclusions
Survival outcomes after CRS + HIPEC for PMP are excellent. The PSOGI pathological classification correlates with OS and DFS, but differences were not significant at multivariate analysis when adjusted for other prognostic factors.
Linguistic Contact in Perspective: Lateral Coda in Principense Portuguese
Authors: Balduino Amanda Macedo , Torres Vieira Nancy Mendes , Agostinho Ana Lívia 
Published: April 2023

AbstractThis paper discusses the lateral /l/ in coda in Principense Portuguese (PP). Based on an elicitedcorpusrecordedin situ, composed of 852 occurrences of 78 lexical items, we found that the lateral /l/ in coda can be vocalized or deleted. For instance,bolso‘pocket’ can be pronounced as [ˈbow.sʊ] or [ˈbo.sʊ], as reported in some Brazilian Portuguese varieties. In PP, vocalization and deletion are phenomena that arise from a confluence of factors. It gathers characteristic features of the formative grammatical structure of Portuguese. At the same time, it reflects the linguistic contact scenario in which PP is inserted, since the lenition of consonants in semivowels, as well as strategies to avoid codas, are also reported in Lung’Ie (LI), a language in synchronic contact and present in the constitution of the PP (Agostinho, Ana Lívia. 2015.Fonologia e método pedagógico do lung’Ie[Phonology and pedagogical method of Lung’Ie]. São Paulo: University of São Paulo dissertation). Both Portuguese and Lung’Ie support vocalization and deletion in their grammars, fostering a relevant overlap of features to the alternation [ɫ] ∼ [w] ∼ ∅ in PP. We conclude that, in addition to specific features of Portuguese grammatical structure, PP’s linguistic contact situation must be considered as a relevant factor for the deletion and vocalization of laterals in coda in PP.
Congenital cerebral and cerebellar anomalies in relation to bovine viral diarrhoea virus and Akabane virus in newborn calves
Authors: Golchin Diba , Sasani Farhang , Moosakhani Farhad , Badiei Arya , Zafari Mohsen , Partovi Nasr Minoo 
Published: April 2023

AbstractCongenital malformations occur sporadically in cattle; however, congenital structural and functional disorders of the nervous system are rather common in ruminants. Among the numerous causes of congenital nervous system defects, infectious agents are highlighted in this paper. Virus-induced congenital malformations are well known, among which those caused by bovine viral diarrhoea virus (BVDV), Akabane virus (AKAV), Schmallenberg virus (SBV), Bluetongue virus (BTV), and Aino virus (AV) are the most studied. In this study, we specify and categorise macroscopic and histopathological lesions in the brain of 42 newborn calves suffering from severe neurologic signs and diagnosed with BVDV and AKAV infection. Following a complete necropsy, specimens were collected from the brains to track the presence of BVDV, AKAV and SBV utilising reverse transcription polymerase chain reaction. Of the 42 examined calves, 21 were BVDV positive and 6 were AKAV positive, while 15 brains were negative for the studied agents. Regardless of the aetiology, cerebellar hypoplasia, hydranencephaly, hydrocephalus, porencephaly, and microencephaly were detected. Cerebellar hypoplasia was the most common lesion seen in both BVDV-positive and AKAV-positive cases. Virus-induced necrosis of the germinative cells of the external granular layer of cerebellum, as well as vascular damages, are believed to be the underlying causes of cerebellar hypoplasia. BVDV was the most important aetiological agent of such cases in this study.
Improving structural health monitoring with impact zone localization using heuristic algorithms
Authors: El-Bakari Abdelali , Khamlichi Abdellatif , Jacquelin Eric 
Published: April 2023

AbstractThis paper presents a novel approach for reconstructing the characteristics of non-punctual impact events on elastic plates by introducing multi-parameter optimization. The objective function is minimized using two heuristic optimization techniques, particle swarm optimization, and differential evolution, to reconstruct impact force characteristics. The force was regarded as taking the form of a uniform pressure over a part of the plate called the patch. The Maxwell-Betti theorem was considered to decouple the problem of localization and the time history of the applying unknown load. The approach based on heuristic optimization methods has been proven a performance to locate the impact zone. A comparison between particle swarm optimization and differential evolution was discussed.
Design intervention of adaptive reuse for historic districts in Qingdao, China
Authors: Liu Sha Sha , He De Kun , Kovács-Andor Krisztián 
Published: April 2023

AbstractChinese city growth has transitioned recently. Urban regeneration that fits local conditions has replaced rapid urbanization. City modernization and historic preservation often clash. Qingdao's ancient blocks need preservation and utilization to develop responsibly. This article aims to investigate the design interventions of adaptive reuse using in practical preserved projects. The study intends to give relevant participants interventions to consider while renovating historic districts to make theories, concepts, and plans guide, promote, and constrain the practice. It should also offer practical solutions to historic city renovation issues.
Machine Learning Approach for Comparative Analysis of De-Noising Techniques in Ultrasound Images of Ovarian Tumors
Authors: Patil Smital D. , Deore Pramod J. 
Published: April 2023

Ovarian abnormalities such ovarian cysts, tumors, and polycystic ovaries are one of the serious disorders affecting women's health. In ultrasound imaging of ovarian abnormalities, noise during capturing of the image and its transmission process frequently corrupts the image. In order to make the best judgments possible at the appropriate moment, ovarian cysts in females must be accurately detected. In computer aided diagnosis of ovarian tumors, preprocessing is a very important step. In preprocessing, de-noising of medical images is a particularly a difficult task since it must be done while maintaining image features that are essential for diagnosis. In this research work we are using various denoising filters on ultrasound images of ovarian tumors. For different noise denoising techniques, performance measures like MSE, PSNR, SSIM, and UQI etc. are calculated. According to experimental findings, Block matching 3-D filter outperforms all other methods. Radiologists can better diagnose the condition with the use of this computer-assisted system.
Bunga Matahari sebagai Simbol Perempuan dalam Cipta Kreasi Batik Lukis dengan Teknik Pewarnaan Glow In The Dark
Authors: Prasetyan Alfia Bella , Ratnawati Ike , Sidyawati Lisa 
Published: April 2023

Perempuan dan bunga matahari merupakan dua wujud yang berbeda tetapi memiliki sifat yang sama. Bunga matahari memiliki keunikan mengikuti arah matahari bergerak dan filosofi bunganya dihubungkan dengan simbol feminitas atau sifat perempuan. Lemah lembut dan sabar terkadang masih diposisikan tidak adil dalam suatu budaya yang disebut patriarki. Sistem sosial yang menempatkan perempuan di kelas terbawah, kekuasaan lebih didominasi laki-laki sehingga banyak kasus pelecehan dan kekerasan atas tubuh perempuan. Dari permasalahan tersebut masih sering terjadi di era modern ini sehingga penulis menjadikan latar belakang dalam pembuatan karya, yang mana makna dibalik karya ini diharapkan bisa menjadi jembatan khususnya bagi perempuan untuk menyuarakan penderitaannya. Tujuan penciptaan ini mendeskripsikan ide gagasan konsep, proses kreatif, hasil dan penyajian batik lukis yang terinspirasi dari bunga matahari sebagai simbol perempuan. Penulis mengembangkan metode Alma M. Hawkins pada pengciptaannya melalui tiga tahapan, yaitu tahap eksplorasi, improvisasi, dan perwujudan. Penyajian hasil karyanya meng-hasilkan enam batik lukis dengan judul: Nirmala, Gundah, Sadrah, Nirwana, Angkara, dan Senandika. Menggunakan dua teknik yaitu teknik colet dan canting tulis untuk pewarna glow in the dark, hasil akhir penciptaan ini diharapkan dapat menjadi inspirasi dalam mengembangkan teknik baru pada batik lukis modern.
Kata kunci: bunga matahari, simbol, perempuan, batik lukis, glow in the dark
The Sunflowers as a Symbol of Women in the Creation of Batik Painting Creations using Coloring Techniques Glow in The Dark
Women and sunflowers are two different forms but have the same characteristics. Sunflowers have the uniqueness of following the direction of the moving sun, a social system that places women in the lowest class, power is dominated by men so that there are many cases of harassment and violence against women's bodies. These problems still often occur in this modern era, so the author uses the background in making works, where the meaning behind this work is hoped to be a bridge, especially for women to voice their suffering. The purpose of this creation is to describe the concept ideas, creative processes, results and presentation of painted batik inspired by sunflowers as a symbol of women. The author develops Alma M. Hawkins' method of creation through three stages, namely the stages of exploration, improvisation, and embodiment. The presentation of his work resulted in six painted batiks with the titles: Nirmala, Gundah, Sadrah, Nirwana, Angkara, and Senandika. Using two techniques, namely the dab and canting techniques for glow in the dark coloring, the final result of this creation is expected to be an inspiration in developing new techniques in modern painting batik.
Keywords: sunflowers, symbols, woman, painted batik, glow in the dark