bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mendelian randomization analysis suggests no associations of herpes simplex virus infections with systemic lupus erythematosus
Authors: Chang Min‐Jing , Liu Meng‐Ting , Chen Miao‐Ran , Li Nan , Zhao Yu‐Hui , Zhang Sheng‐Xiao , He Pei‐Feng , Yu Qi 
Published: March 2023

AbstractSystemic lupus erythematosus (SLE) characterized by immune dysfunction is possibly more vulnerable to herpes simplex virus (HSV) infection. The infection has been intensively considered a common onset and exacerbation of SLE. This study is aimed at elucidating the causal association between SLE and HSV. A bidirectional two‐sample Mendelian Randomization (TSMR) analysis was systematically conducted to explore the causal effect of SLE and HSV on each other. The causality was estimated by inverse variance weighted (IVW), MR‐Egger and weighted median methods based on the summary‐level genome‐wide association studies (GWAS) data from a publicly available database. Genetically proxied HSV infection exhibited no causal association with SLE in the forward MR analysis using IVW method (odds ratio [OR] = 0.987; 95% confidence interval [CI]: 0.891–1.093; p = 0.798), nor did HSV‐1 IgG (OR = 1.241; 95% CI: 0.874–1.762; p = 0.227) and HSV‐2 IgG (OR = 0.934; 95% CI: 0.821–1.062; p = 0.297). Similar null results with HSV infection (OR = 1.021; 95% CI: 0.986–1.057; p = 0.245), HSV‐1 IgG (OR = 1.003; 95% CI: 0.982–1.024; p = 0.788) and HSV‐2 IgG (OR = 1.034; 95% CI: 0.991–1.080; p = 0.121) were observed in the reverse MR where SLE served as the exposure. Our study demonstrated no causal association between the genetically predicted HSV and SLE.
Social interactions in trauma disclosure: A multi‐informant and multiconstruct investigation
Authors: Ennis Naomi , Wagner Anne C. , Hart Tae L. , Monson Candice M. 
Published: March 2023

AbstractResearch has established that social factors are integral to trauma recovery. Yet, there is relatively little data on the association between social interactions from different supports and posttraumatic stress disorder (PTSD) symptoms. Moreover, few studies have measured these factors from multiple informants. This paper examined social interactions from different sources (i.e., negative and positive reactions from a chosen close other [CO], family/friends, and general non‐COs) and their association with PTSD symptoms using multi‐informant reports of the social constructs (i.e., from the individual exposed to trauma [TI] and their CO). Participants (N = 104 dyads) were recruited from an urban center within 6 months of the TIs’ exposure to a traumatic event. TIs were assessed using the Clinician‐Administered PTSD Scale. TI self‐report, t(97) = 2.58, p = .012, and CO collateral report of disapproval from family/friends, t(97) = 2.14, p = .035, and TI self‐report of general disapproval, t(97) = 4.91, p < .001, emerged as significant predictors of PTSD symptoms when compared with other social constructs. Interventions that target family members’ and friends’ reactions to trauma survivors and societal discourse around trauma and reactions to trauma survivors are recommended. Clinical interventions that buffer against TIs’ experiences of disapproval and guide COs on the provision of supportive responses are discussed.
The Value of Ultrasound for Differentiating Trichilemmal Cysts From Epidermoid Cysts
Authors: Ren Wei‐Wei , Wu Ling , Wang Qiao , Shan Dan‐Dan , Wang Li‐Fan , Chen Zi‐Tong , Li Liang , Sun Li‐Ping , Guo Le‐Hang , Xu Hui‐Xiong 
Published: March 2023

ObjectivesThis study was aimed to evaluate the diagnostic performance of ultrasound (US) in differentiating trichilemmal cysts (TCs) from epidermoid cysts (ECs).MethodsBased on clinical and ultrasound features, a prediction model was established and validated. 164 cysts in the pilot cohort and another 69 in the validation cohort diagnosed with TCs or ECs histopathologically were evaluated. The same radiologist performed all ultrasound examinations.ResultsFor clinic features, TCs tended to occur in females compared with ECs (66.7 vs 28.5%; P < .001). In addition, TCs were prone to occur in the hairy area compared with ECs (77.8 vs 13.1%; P < .001). For ultrasound features, the internal hyperechogenicity and cystic change were more likely to appear in TCs in comparison with ECs (92.6 vs 25.5%; P < .001; 70.4 vs 23.4%; P < .001, respectively). Upon the features mentioned above, a prediction model was established with the areas under the receiver operating characteristic curves of 0.936 and 0.864 in the pilot and validation cohorts, respectively.ConclusionsUS is promising for differentiating TCs from ECs and is valuable for their clinical management.
Zwitterionic Polymer Brushes and Core‐Shell Particles Based thereon for Control of Biofouling
Authors: Kopsch Fabian , Drechsler Astrid , Priebs Martina , Caspari Anja , Müller Anett , Lentz Sarah , Friedrichs Jens , Synytska Alla 
Published: March 2023

AbstractBiofilm formation on material surfaces – biofouling – has a significant economic impact on a wide range of applications and industries. There is a huge need for the prevention of undesired interactions of coatings with proteins, cells, and bacteria in biomaterials, biosensors, and other applications. In this work, the preparation and characterization as well as the comparison of bio‐fouling properties of surfaces based on planar zwitterionic polymer brushes made of poly(sulfobetaine methacrylate) P(SBMA‐3), poly(carboxybetaine methacrylate) P(CBMA‐2), or poly(2‐methacryloyloxyethyl phosphorylcholine) P(MPC‐2) are reported. Since polymer brushes on planar surfaces have disadvantages with regard to layer stability, industrial scaling, and the coating of complex geometries, nano‐ and microstructured coatings based on polymer‐functionalized core‐shell particles are subsequently produced. It is found that coatings based on poly(phosphorylcholine) P(MPC‐2) modified particles with a diameter of 100 nm have the lowest bioadhesion compared to other particle sizes and chemical compositions. The particle‐based coatings developed can pave the way for developing scalable anti‐fouling coatings in the future.
Retailers' information disclosure strategies with behavior‐based pricing in competitive supply chains
Authors: Ma Peng , Lu Yujia , Wang Haiyan , Wen Danping 
Published: March 2023

AbstractIn this paper, we investigate information disclosure strategies with behavior‐based pricing (BBP) of retailers in a competitive channel with consumers' valuation uncertainty. We analyze the impacts of disclosure strategies (i.e., disclosing by an individual retailer and disclosing by both retailers) with BBP on the pricing decisions and profits of supply chain members. Then, we investigate the effects of the probability of a high valuation on supply chain members. We find that (i) the profits of manufacturers and retailers with BBP and information disclosure are always higher than those with BBP; (ii) the profits of manufacturers and retailers when both retailers implement BBP and use information disclosure are always higher than those when one retailer implements BBP and uses information disclosure; and (iii) the profits of manufacturers and retailers decrease with the probability of a high valuation first and then increase with it when both retailers implement BBP and use information disclosure.
A preliminary evaluation of positive self‐review as an oral reading fluency intervention
Authors: Wu Shengtian , Gadke Daniel L. 
Published: March 2023

AbstractVideo self‐modeling (VSM) has been used to improve the social behaviors of students from diverse backgrounds. However, its application to reading fluency is still in the preliminary stage. VSM can be divided into feedforward VSM (FFVSM) and positive self‐review (PSR). Previous studies examined the effect of stand‐alone FFVSM and its effect when adding it to intervention packages or repeated reading (RR). However, no study has examined the effect of PSR on improving reading fluency. Following a baseline phase, an alternating treatments design compared the control, PSR, RR, and PSR + RR conditions. The comparisons evaluated the stand‐alone effect of PSR and the effect of PSR as an intervention component when added to RR. The extended analysis and follow‐up phase validated the most effective intervention identified in the alternating treatments phase for each participant and evaluated the long‐term effect of the most effective interventions. Based on visual analysis and two effect size measurements (Nonoverlaps of All Pairs and Tau‐U), PSR was found to be effective for only one of three elementary school students with disabilities. Moreover, RR was more effective than the stand‐alone PSR for the participants. Practical implications, limitations, and future studies are discussed.
Nussbaum‐based robust adaptive control for nonlinear switching systems with switching unknown control coefficients
Authors: Tang Liqiang , Yang Yongliang , Chen Xianzhong , Li Qing 
Published: March 2023

AbstractThis paper develops a robust adaptive dynamic surface control (DSC) design approach for switching strict feedback nonlinear systems with multiple switching control gains and unknown control directions. To capture the multiple unknown control directions, we design multiple Nussbaum‐type gains for every subsystem. Based on this Nussbaum‐type gain design, we construct a common Lyapunov function for all subsystems via backstepping technique, which can ensure the system stability under the existence of random switches. Meanwhile, the problem of multiple switching control gains is resolved by this means. To obviate repeated differentiation and decrease computation complexity, the dynamic surface control technique is introduced. Finally, two simulation examples are provided to validate the effectiveness of the developed method.
When Super‐Resolution Microscopy Meets Microfluidics: Enhanced Biological Imaging and Analysis with Unprecedented Resolution
Authors: Yang Wei , Hou Lei , Luo Chunxiong 
Published: March 2023

AbstractSuper‐resolution microscopy is rapidly developed in recent years, allowing biologists to extract more quantitative information on subcellular processes in live cells that is usually not accessible with conventional techniques. However, super‐resolution imaging is not fully exploited because of the lack of an appropriate and multifunctional experimental platform. As an important tool in life sciences, microfluidics is capable of cell manipulation and the regulation of the cellular environment because of its superior flexibility and biocompatibility. The combination of microfluidics and super‐resolution microscopy revolutionizes the study of complex cellular properties and dynamics, providing valuable insights into cellular structure and biological functions at the single‐molecule level. In this perspective, an overview of the main advantages of microfluidic technology that are essential to the performance of super‐resolution microscopy are offered. The main benefits of performing super‐resolution imaging with microfluidic devices are highlighted and perspectives on the diverse applications that are facilitated by combining these two powerful techniques are provided.
Perovskite‐Nanocrystal‐Doped Cellulose Nanocrystal Ligands for Electrospun Nanofibers with Excellent Stability
Authors: Chen Wei‐Cheng , Chen Lung‐Chih , Liu Fu‐Jie , Tsai Wei‐Chen , Tung Bo‐Han , Venkatesan Manikandan , Tsai Meng‐Lin , Lin Ja‐Hon , Kuo Chi‐Ching 
Published: March 2023

AbstractBecause of their exceptional physical and thermal properties, cellulose nanocrystals (CNCs) are a highly promising bio‐based material for reinforcing fillers. Studies have revealed that some functional groups from CNCs can be used as a capping ligand to coordinate with metal nanoparticles or semiconductor quantum dots during the fabrication of novel complex materials. Therefore, through CNCs ligand encapsulation and electrospinning, perovskite‐NC‐embedded nanofibers with exceptional optical and thermal stability are demonstrated. The results indicate that, after continuous irradiation or heat cycling, the relative photoluminescence (PL) emission intensity of the CNCs‐capped perovskite‐NC‐embedded nanofibers is maintained at ≈90%. However, the relative PL emission intensity of both ligand‐free and long‐alkyl‐ligand‐doped perovskite‐NC‐embedded nanofibers decrease to almost 0%. These results are attributable to the formation of specific clusters of perovskite NCs along with the CNCs structure and thermal property improvement of polymers. CNCs‐doped luminous complex materials offer a promising avenue for stability‐demanding optoelectronic devices and other novel optical applications.
Molecular phylogenetic assessment of three major taxa in the Asplenium scolopendrium complex (Aspleniaceae)
Authors: Heo Namjoo , Yun Seona , Fernando Danilo D. 
Published: March 2023

AbstractTaxonomic ambiguities of the Asplenium scolopendrium complex arise from multiple synonyms and reclassifications, subtle phenotypic variations, and a lack of information on phylogenetic relationships. This study thus aimed to resolve this taxonomic uncertainty and provide insight into identifying evolutionarily significant units (ESUs). We first utilized genomic approaches to resolve the phylogenetic position of the East Asian taxon, A. komarovii, which is currently treated as a separate species. Phylogenetic trees based on whole plastomes suggested that A. komarovii is a variant of A. scolopendrium most closely related to A. scolopendrium var. americanum, with A. scolopendrium var. scolopendrium as the sister to these in the clade. This three‐lineage relationship was also validated with the nuclear marker gapCp and newly developed infraspecific plastid markers. Asplenium komarovii should therefore be subsumed into A. scolopendrium, rather than remaining a distinct species. In addition, our phylogenetic analyses further revealed that A. scolopendrium var. americanum consisted of subclades with potential to be treated as distinct ESUs. Our results also grouped a newly discovered population from New Mexico (U.S.A.) as a member of A. scolopendrium var. americanum and identified a genetically admixed population in New York (U.S.A.) containing putative hybrids. Well‐defined taxonomy and ESUs can greatly improve the implementation of tailored conservation actions by adequately reflecting the underlying evolutionary potentials of the A. scolopendrium complex.
Relationships between undergraduate instructors' conceptions of how students learn and their instructional practices
Authors: Idsardi Robert C. , Luft Julie A. , Wingfield Jenna L. , Whitt Blake , Barriga Paola A. , Lang Jason D. 
Published: March 2023

AbstractSupporting changes in undergraduate science, technology, engineering, and mathematics (STEM) instruction requires an understanding of the relationship between STEM instructors' conceptions and practices. In this study, the authors used the Teacher‐Centered Systematic Reform (TCSR) model as a framework to understand how instructors' conceptions are related to their instructional practices. This multiple methods study included interviews and classroom observations of 22 STEM instructors. We used qualitative methods to describe instructors' conceptions of how students learn and quantitative methods, including a hierarchical cluster analysis, to analyze the types of relationships that exist between their conceptions and practices. Results indicated instructors had a wide range of conceptions that exist along a continuum from teacher‐centered to student‐centered. While many faculty members perceived student‐centered practices as valuable, they conceptualized these practices in different ways. Instructors implemented a wide range of instructional practices, and these practices varied independently of conceptions. We identified three distinct clusters of participants based on the relationships between instructors' conceptions and practices: congruent lecturers, congruent active learning facilitators, and incongruent lecturers. In the first two clusters, instructors' conceptions were aligned with their instructional practices. However, incongruent lecturers thought that students learn through active learning approaches but primarily lectured in their courses. Instructors in this group described several personal and contextual factors that influenced the relationship between their conceptions and practices. The results include an in‐depth portrayal of one participant in each cluster. We found that student‐centered conceptions may be necessary but are not sufficient for instructors to implement active learning. Implications focus on instructional and institutional change efforts. To promote instructional change most effectively, it is important to address each component of the TCSR model, including personal and contextual factors. A focus on conceptions and practices alone may not sufficiently support faculty members in overcoming barriers that limit active learning instruction.
IGTCM: An integrative genome database of traditional Chinese medicine plants
Authors: Ye Yuan‐Nong , Liang Ding‐Fa , Yi Jia‐Hao , Jin Shuai , Zeng Zhu 
Published: March 2023

AbstractFully understanding traditional Chinese medicines (TCMs) is still challenging because of the extreme complexity of their chemical components and mechanisms of action. The TCM Plant Genome Project aimed to obtain genetic information, determine gene functions, discover regulatory networks of herbal species, and elucidate the molecular mechanisms involved in the disease prevention and treatment, thereby accelerating the modernization of TCMs. A comprehensive database that contains TCM‐related information will provide a vital resource. Here, we present an integrative genome database of TCM plants (IGTCM) that contains 14,711,220 records of 83 annotated TCM‐related herb genomes, including 3,610,350 genes, 3,534,314 proteins and corresponding coding sequences, and 4,032,242 RNAs, as well as 1033 non‐redundant component records for 68 herbs, downloaded and integrated from the GenBank and RefSeq databases. For minimal interconnectivity, each gene, protein, and component was annotated using the eggNOG‐mapper tool and Kyoto Encyclopedia of Genes and Genomes database to acquire pathway information and enzyme classifications. These features can be linked across several species and different components. The IGTCM database also provides visualization and sequence similarity search tools for data analyses. These annotated herb genome sequences in IGTCM database are a necessary resource for systematically exploring genes related to the biosynthesis of compounds that have significant medicinal activities and excellent agronomic traits that can be used to improve TCM‐related varieties through molecular breeding. It also provides valuable data and tools for future research on drug discovery and the protection and rational use of TCM plant resources. The IGTCM database is freely available at http://yeyn.group:96/.
Approximate Inference in Probabilistic Answer Set Programming for Statistical Probabilities
Authors: Azzolini Damiano , Bellodi Elena , Riguzzi Fabrizio 
Published: March 2023

Abstract“Type 1” statements were introduced by Halpern in 1990 with the goal to represent statistical information about a domain of interest. These are of the form “x% of the elements share the same property”. The recently proposed language PASTA (Probabilistic Answer set programming for STAtistical probabilities) extends Probabilistic Logic Programs under the Distribution Semantics and allows the definition of this type of statements. To perform exact inference, PASTA programs are converted into probabilistic answer set programs under the Credal Semantics. However, this algorithm is infeasible for scenarios when more than a few random variables are involved. Here, we propose several algorithms to perform both conditional and unconditional approximate inference in PASTA programs and test them on different benchmarks. The results show that approximate algorithms scale to hundreds of variables and thus can manage real world domains.
Moduli stabilization in type IIB orientifolds at h2,1 = 50
Authors: Tsagkaris Konstantinos , Plauschinn Erik 
Published: March 2023

Abstract
We study moduli stabilization in Calabi-Yau orientifold compactifications of type IIB string theory with O3- and O7-planes. We consider a Calabi-Yau three-fold with Hodge number h2,1 = 50 and stabilize all axio-dilaton and complex-structure moduli by three-form fluxes. This is a challenging task, especially for large moduli-space dimensions. To address this question we develop an algorithm to generate 105 flux vacua with small flux number Nflux. Based on recent results by Crinò et al. we estimate the bound imposed by the tadpole-cancellation condition as Nflux≤$$ \mathcal{O} $$
O
(103), however, the smallest flux number we obtain in our search is of order Nflux = $$ \mathcal{O} $$
O
(104). This implies, in particular, that for all solutions to the F-term equations in our data set the tadpole conjecture is satisfied.
A Characterisation of Orthomodular Spaces by Sasaki Maps
Authors: Lindenhovius Bert , Vetterlein Thomas 
Published: March 2023

AbstractGiven a Hilbert space H, the set P(H) of one-dimensional subspaces of H becomes an orthoset when equipped with the orthogonality relation ⊥ induced by the inner product on H. Here, an orthoset is a pair (X,⊥) of a set X and a symmetric, irreflexive binary relation ⊥ on X. In this contribution, we investigate what conditions on an orthoset (X,⊥) are sufficient to conclude that the orthoset is isomorphic to (P(H),⊥) for some orthomodular space H, where orthomodular spaces are linear spaces that generalize Hilbert spaces. In order to achieve this goal, we introduce Sasaki maps on orthosets, which are strongly related to Sasaki projections on orthomodular lattices. We show that any orthoset (X,⊥) with sufficiently many Sasaki maps is isomorphic to (P(H),⊥) for some orthomodular space, and we give more conditions on (X,⊥) to assure that H is actually a Hilbert space over $\mathbb R$
ℝ
, $\mathbb C$
ℂ
or $\mathbb H$
ℍ
.