bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN ANTARA PEMBELAJARAN DALAM JARINGAN (DARING) DENGAN TINGKAT STRES SELAMA PANDEMI COVID-19 PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MALAHAYATI BANDAR LAMPUNG ANGKATAN 2019
Authors: Risky Ririn Pearl , Sahara Nita , Sudiadnyani Ni Putu , Lestari Sri Maria Puji 
Published: January 2023

Virus Corona merupakan virus baru yang masih belum terindentifikasi pada manusia sebelumnya, sehingga disebut 2019 Novel Coronavirus atau 2019-nCoV. Dengan adanya kebijakan WFH hampir semua perguruan tinggi di Indonesia melakukan pembelajaran Daring. Mekanisme adaptasi dari perkuliahan secara tatap muka menjadi perkuliahan Daring menurut beberapa teori dapat menimbulkan stress. Stres merupakan pengalaman paling sering dialami dalam lingkungan akademik, baik yang sedang belajar di tingkat sekolah ataupun perguruan tinggi. Penelitian ini diketahui hubungan antara pembelajaran Daring dengan tingkat stres selama pandemi Covid-19 pada mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Malahayati Bandar Lampung Angkatan 2019. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional. Populasi pada penelitian adalah semua mahasiswa angkata 2019 sejumlah 136 orang, Sampel pada penelitian ini sejumlah 102 orang. Pengumpulan data menggunakan kuesioner. Analisis hubungan menggunakan uji Chi Square. Responden menyatakan pembelajaran Daring tidak efektif yaitu berjumlah 58 orang (56.9%), tidak mengalami stress yaitu berjumlah 65 orang (63,7%). Hasil penelitian menunjukkan ada hubungan antara pembelajaran Daring dengan tingkat stres selama pandemi Covid-19 pada mahasiswa Program Studi Kedokteran Fakultas Kedokteran Universitas Malahayati Bandar Lampung Angkatan 2019 (p value 0,007, OR 3,63). Ada hubungan antara pembelajaran Daring dengan tingkat stres selama pandemi Covid-19.
Pengaruh Good Corporate Governance dan Leverage terhadap Kinerja Keuangan (Studi pada Perusahaan Manufaktur yang terdaftar di BEI)
Authors: Agustina Nita , Aprianti Kartin 
Published: January 2023

Purpose of this study to explain how much influence good corporate governance and leverage can affect financial performance. Data was collected bt targeting random sampling from 6 cemen sub-sector companies listed on the Indonesian Stock Exchange between 2016-2020. Multiple linear analysis was used as the analytical method. then tested the hypothesis with a partial T test and simultaneous F test with the determinant coefficient with a significance level of 5%. Management supervision carried out by independent commissioners does not a significant impact on financial performance. Many or at least the number of audit committees in a company does not significant impact on financial performance. low leverage has a significant impact on financial performance. However based on a simultaneous reviews, the combination of independent commissioners, audit committees and leverage has a significant impact on financial performance.
Dampak Pandemi Covid-19 Pada Aktivitas Ekspor-Impor Provinsi Lampung (Studi Pada PT. Pelabuhan Indonesia Cabang Panjang)
Authors: Suryani Suryani , Susanty P Melan 
Published: January 2023

This study aims to determine the development of export and import activities in Lampung Province during the Covid-19 pandemic, especially at the Port of Panjang-Bandar Lampung. The type of research used is qualitative research, and the sampling technique uses purposive sampling method. This research is expected to provide information or knowledge for exporters, importers, related institutions, especially port managers. Based on the results of the study, export and import activities in Lampung Province through the Port of Panjang-Bandar Lampung experienced a significant decline during the Covid-19 pandemic. The impact of the Covid-19 pandemic is not only on the health sector, but also has a significant impact on the economic and business sectors, especially in export and import activities.
Analisis Faktor – Faktor Yang Mempengaruhi Penggunaan Informasi Akuntansi Pada UMKM Di Bandar Lampung
Authors: Astuti Sri , Irawan Irawan , Sidik Muhammad Muhayyin 
Published: January 2023

Pengembangan dan pertumbuhan UMKM merupakan salah satu motor penggerak yang krusial bagi pembangunan ekonomi. Berdasarkan pengalaman di negara-negara maju menunjukkan bahwa UMKM adalah sumber dari inovasi produksi dan teknologi, pertumbuhan jumlah wirausahawan yang kreatif dan inovatif dan penciptaan tenaga kerja terampil dan fleksibel dalam proses produksi.Tujuan dari penelitian ini adalah menganalisis faktor-faktor yang berpengaruh terhadap penggunaan informasi akuntansi bagi UMKM. Faktor-faktor tersebut adalah jenjang pendidikan pemilik,lama usaha, skala usaha,dan pengetahuan pemilik tentang informasi akuntansi apakah berpengaruh terhadap penggunaan informasi akuntansi.Hasil penelitian ini sangat penting untuk para pelaku UMKM di Kota Bandar Lampung untuk lebih memahami dan memanfaatkan informasi akuntansi dalam penyusunan laporan keuangannya. Hasil penelitian ini juga dapat dijadikan dasar bagi Pemerintah Kota Bandar Lampung dalam menambahkan berbagai langkah strategis dalam memberikan pembinaan dan pendampingan UMKM dan melakukan evaluasi terhadap capaian yang selama ini sudah dilakukan dalam rangka mendukung program Pemerintah Kota untuk semakin memberdayakan UMKM.
Accuracy Assessment of “Step-by-Step” Simulation Modeling Method for Rock Breaking by TBM Disc Cutters Assisted with Laser
Authors: Zhang Kui , Kuang Minghai , Liu Jingang , Zheng Xuejun , Qiao Shuo 
Published: January 2023

Rock breaking by laser-assisted disc cutters is a novel high-efficiency rock breaking mode that combines mechanical stress induced by the disc cutters with thermal cracking by laser. This paper presented a “step-by-step” simulation modeling concept, and conducted an in-depth study on potential influencing factors of simulation accuracy at each key step. First, the prediction accuracy of laser holes in laser drilling simulation was discussed. Second, the SHPB simulation and experiment were carried out to evaluate the accuracy of the selected material constitutive model in simulating the dynamic fracture damage of rock. Then, taking the laser-assisted rock-penetrating process of the scaled disc cutter as an example, the simulation prediction accuracy of rock-breaking by the disc cutter was analyzed. Finally, the simulation and experiment of laser-assisted disc cutter penetration into rock was carried out, and then the feasibility of the “step-by-step” concept was analyzed. The results show that: (1) in the laser drilling simulation, the predicted accuracy of laser hole size is higher when the power is low; with the laser power increases, the large amount of glass glaze will affect the subsequent modeling accuracy; (2) the HJC model can be used to simulate the transient nonlinear fracture damage behavior of granite; (3) the damage morphology of the granite obtained by the penetration simulation is highly similar to the experimental results, and the load curve should be corrected by the peak point fitting method. The results show the application prospects of the proposed numerical modeling method in future laser-assisted TBM tunnelling.
Esposito And Machiavelli: Inspiration And Affinity
Authors: Pugliese Olga Zorzi 
Published: January 2023

Esposito's early essays, from the 1980s, on Machiavelli's The Prince and The Discourses reveal affinities between the two thinkers: the stress on innovation and originality, the goal of concreteness and functionality, and the effective use of rhetorical modes of expression, including metaphorical language (the image of the pathway, for example). Esposito's non-conventional manner of interpreting Machiavelli, which excludes questions of chronology or biography, and presents a non-linear analysis of the texts, expressed in vivid prose, help explain the modern philosopher's view of the Renaissance author as a precursor in the Italian tradition of what he calls living thought or Italian theory.
Xenophon's Anabasis
Authors: Brennan Shane 
Published: January 2023

Xenophon's Anabasis tells the story of Cyrus the Younger’s failed rebellion against his brother, the Persian King, in 401 BCE and of what happened afterwards to the Ten Thousand Greek mercenaries who enlisted in his army. The account provides a vivid insight into the lived experience of the journey and the key events that defined it. Through his telling of the story, Xenophon furthermore integrates a number of the themes and concerns that recur across his oeuvre, including leadership, panhellenism, Sparta and apologia. Adopting an interdisciplinary perspective, Brennan offers a fresh reading of the text which originates in a broad-ranging consideration of Xenophon’s aims in writing the book some thirty years after the event. The central argument brings the presence of Socrates into relief and demonstrates how the author, representing himself in the story as a model pupil of the philosopher, perpetuates Socratic teachings and values through ‘Xenophon’s’ leadership. Ultimately, Anabasis is revealed to be a ‘Socratic history’, a narrative rooted in a historical event or period and in which the author embeds a reflection of the philosopher and his values.
Japanese High School Films
Authors: Pugsley Peter C. 
Published: January 2023

Japanese High School Films: Iconography, Nostalgia and Discipline explores how contemporary films set in high schools capture a distinct view of Japanese adolescent life, uncovering significant links with the themes of discipline and institutionalisation that underpin Japanese society. It illustrates how Japanese high school films link directly to manga, anime, TV dramas and pop music, triggering audience recognition and nostalgia through on-screen use of iconographic images, from school uniforms to rooftop recreational spaces. This book identifies universal themes of teen romance, friendship, and bullying, and the spatial and temporal changes that affect every student’s journey. The casting of already-famous music and fashion celebrities as students and as teachers allows the films to capitalise on cross-generational fandom across Japan’s prolific entertainment and popular culture industries. Drawing on established Japanese film aesthetics, some high school films explore taboo student-teacher relationships, adolescent sexuality, and the possibility of teen same-sex relationships. Japanese High School Films is the first book to give a detailed account of this popular cinematic genre that informs us about contemporary Japanese culture.
A Call to Dissent
Authors: Sim Stuart 
Published: January 2023

Dogmatism, prejudice and bigotry are becoming ever more evident in Western politics. Divisive governments looking to cement their power strive to close down anyone who disagrees with them: political opponents, members of their own parties, the mainstream media, educators, protesters and, ultimately, voters. The political right have declared 'war' on 'woke', as though it was wrong to believe in social justice and respect for beliefs and opinions other than one's own. That is, to support the principles of liberal democracy.
A Call to Dissent defends dissent as an essential part of democracy. It argues that the political left are falling into despair in the face of growing right-wing populism, rather than challenging and standing up to it. Taking a wide-ranging view, the book identifies how dissent works in philosophy, religion, science and the arts as well as in politics. Ultimately, it calls on all of us to become dissenters ourselves in order to challenge authoritarianism and counter the growth of prejudice, bigotry, and extremism in public life.
R. B. Cunninghame Graham and Scotland
Authors: Munro Lachlan 
Published: January 2023

This multidisciplinary work explores the complex life of the most controversial and enigmatic Scot of his generation, and his contribution to Scottish life and letters. R. B. Cunninghame Graham was a very well-known and hugely influential figure in late nineteenth and early twentieth-century Scottish politics and literature, and the book explores his early political views, his time as a Member of Parliament, his disillusionment with the Liberal Party, his arrest and imprisonment, and his reputation as the first declared ‘socialist’ M.P. Using documentary evidence and tangible philosophical links, the book traces Graham’s early political influences, derived directly or indirectly from key nineteenth-century figures, particularly William Morris, and his friendships with George Bernard Shaw, Oscar Wilde, and Joseph Conrad. It also examines Graham’s anti-imperialist, anti-colonial and anti-racist speeches and writings, and his active support for women’s rights and universal suffrage, his relationship with Keir Hardie, and their founding of the first party of Labour in Britain, his later active support for Irish and Scottish independence, and his highly original evocations of Scottish landscape and character. The book strips away the mythology surrounding Graham to reveal an altogether more complex picture, exploring his political and literary achievements, during a time of enormous political, economic, and cultural upheaval, the reverberations of which are still ongoing.
Morphological and mechanical alterations in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs
Authors: Gao Jiazi , Ren Pengling , Gong He 
Published: January 2023

Objectives: This study aimed to investigate the morphological and mechanical changes in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs.Materials and methods: Hip joints of guinea pigs were investigated at 1, 3, 6, and 9 months of age (hereafter denoted as 1 M, 3 M, 6 M, and 9 M, respectively; n = 7 in each group). Morphological and mechanical alterations during spontaneous hip osteoarthritis in guinea pigs were investigated. The alterations included the micromechanical properties of articular cartilage (stiffness and creep deformation), microstructure of the subchondral bone (bone mineral density, bone volume fraction, trabecular thickness, trabecular number, and trabecular separation), micromorphology of the articular cartilage, and surface nanostructure (grain size and roughness) of the articular cartilage and subchondral bone.Results: Micromechanical properties of articular cartilage in 1 M showed the lowest stiffness and highest creep deformation with no significant differences in stiffness or creep deformation amongst 3 M, 6 M, and 9 M. Articular cartilage thickness decreased with age. The earliest degeneration of articular cartilage occurred at 6 months of age, characterised by surface unevenness and evident chondrocytes reduction in micromorphology, as well as increased grain size and decreased roughness in nanostructure. No degeneration at micro- or nanostructure of subchondral bone was observed before 9 months.Conclusion: Morphological degeneration of cartilage occurred before degeneration of mechanical properties. Meanwhile, degeneration of cartilage occurred before degeneration of subchondral bone during hip osteoarthritis. The current study provided novel insights into the structural and micromechanical interaction of hip osteoarthritis, which can serve as a theoretical basis for understanding the formation and progression of osteoarthritis.
β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway
Authors: Yan Cai-Ping , Wang Xing-Kuan , Jiang Ke , Yin Chong , Xiang Chao , Wang Yong , Pu Chaoyu , Chen Lu , Li Yu-Ling 
Published: January 2023

Graphical AbstractSchematic illustrations of the fabrication of the bone defect model and action of β-Ecd in promoting bone regeneration and repair of bone defects. We established a rat model of a femoral bone defect in vivo to evaluate the effect of β-Ecd on bone regeneration. Rats injected intraperitoneally with 72 mg/kg β-Ecd showed a higher degree of ossification of regenerated bone tissue at the site of the bone defect at weeks 4 and 8. β-ecdysterone binding to the BMP2 receptor activates SMAD1 to bind to SMAD1/5/8, promotes RUNX2 and OSTERIX replication in the nucleus, and mediates bone regeneration. This study provides a new approach to the treatment of bone injury and degenerative diseases represented by bone defects and osteoporosis.
New Yuomys rodents from southeastern Qinghai-Tibet Plateau indicate low elevation during the Middle Eocene
Authors: Ni Xijun , Li Qiang , Deng Tao , Zhang Limin , Gong Hao , Qin Chao , Shi Jingsong , Shi Fuqiao , Fu Shubing 
Published: January 2023

Yuomysare medium-sized Hystricomorpha rodents. They are known for coming from areas of low elevation in China during the middle and late Eocene. Two newYuomyswere discovered from a locality near Xueshuo village in Litang County, Sichuan Province. The locality lies in the Gemusi pull-apart basin formed in the Litang Fault System (LTFS) in the Hengduan Mountains. The current average elevation is about 4200 m. One of the two newYuomysis larger and shows clear lophodont and unilateral hypsodont morphology, similar toYuomys yunnanensis, which was discovered as being from the early middle Eocene (Irdinmanhan, Asian Land Mammal Ages) in the Chake Basin of Jianshui County, Yunnan Province. The Chake Basin is one of the small pull-apart basins formed in the Xianshuihe-Xiaojiang Fault system (XSH-XJF). The other newYuomysrodent is smaller, brachydont, and less lophodont than the larger new species. The small newYuomysis smaller than all knownYuomysexceptYuomys huheboerhensis, which is from the early middle Eocene Irdinmanhan of Inner Mongolia in Northern China. Given their narrow biochronological distribution and presumably preferred living environment, the occurrence ofYuomysin the pull-apart basins in LTFS and XSH-XJF suggests that the two deep fault systems probably started strike-slip movement by the early middle Eocene, about 49–45 million years ago. Well-studied middle Eocene mammalian faunas from Henan and Inner Mongolia includeYuomys, primates, and other low elevation forest mammals. We suggest that the two newYuomysspecies reported here probably also lived in a similar low elevation forest environment.
Nanoscale pore characteristics of the Jurassic Dongyuemiao member lacustrine shale, Eastern Sichuan Basin, SW China: Insights from SEM, NMR, LTNA, and MICP experiments
Authors: Zhou Yadong , Wang Zhanlei , Hu Dongfeng , Wei Zhihong , Wei Xiangfeng , Liu Ruobing , Wang Daojun , Jiang Yuqiang 
Published: January 2023

The Jurassic Dongyuemiao Member is the most promising target for lacustrine shale gas exploration in Sichuan Basin. By integrating SEM, NMR, LTNA, and MICP experiments, and other basic measurements, the nanoscale pore category and structure and the corresponding controlling factors of Dongyuemiao lacustrine shale in Eastern Sichuan Basin are studied. The results denote that organic pores comprise primary pores within plant debris and secondary pores within bitumen. Inorganic pores are composed of intraparticle pores within calcite particles, intercrystalline pores between pyrite crystals, and interparticle pores between different minerals. The 4th Section lacustrine shale of Dongyuemiao Member has the best pore structure, exhibiting high organic pore proportion, large amounts of gas adsorption, and parallel plate-shaped pore morphology. Micropores (&lt;2 nm) are the main contributors of the pore volume and surface area of Dongyuemiao lacustrine shale. Moreover, the enrichment of organic matter positively affects the formation of micropores and has no influence on the mesopore–macropore (&gt;2 nm). Quartz does not significantly affect the nanoscale pore formation. The intraparticle pores within calcite particles constitute part of mesopore–macropore but not micropores. Clay minerals are conducive to the formation of micropores but play a negative role in the formation of mesopore–macropore.
Zebrafish Tric-b is required for skeletal development and bone cells differentiation
Authors: Tonelli Francesca , Leoni Laura , Daponte Valentina , Gioia Roberta , Cotti Silvia , Fiedler Imke A. K. , Larianova Daria , Willaert Andy , Coucke Paul J. , Villani Simona , Busse Björn , Besio Roberta , Rossi Antonio , Witten P. Eckhard , Forlino Antonella 
Published: January 2023

IntroductionTrimeric intracellular potassium channels TRIC-A and -B are endoplasmic reticulum (ER) integral membrane proteins, involved in the regulation of calcium release mediated by ryanodine (RyRs) and inositol 1,4,5-trisphosphate (IP3Rs) receptors, respectively. While TRIC-A is mainly expressed in excitable cells, TRIC-B is ubiquitously distributed at moderate level. TRIC-B deficiency causes a dysregulation of calcium flux from the ER, which impacts on multiple collagen specific chaperones and modifying enzymatic activity, leading to a rare form of osteogenesis imperfecta (OI Type XIV). The relevance of TRIC-B on cell homeostasis and the molecular mechanism behind the disease are still unknown.ResultsIn this study, we exploited zebrafish to elucidate the role of TRIC-B in skeletal tissue. We demonstrated, for the first time, that tmem38a and tmem38b genes encoding Tric-a and -b, respectively are expressed at early developmental stages in zebrafish, but only the latter has a maternal expression. Two zebrafish mutants for tmem38b were generated by CRISPR/Cas9, one carrying an out of frame mutation introducing a premature stop codon (tmem38b-/-) and one with an in frame deletion that removes the highly conserved KEV domain (tmem38bΔ120-7/Δ120-7). In both models collagen type I is under-modified and partially intracellularly retained in the endoplasmic reticulum, as described in individuals affected by OI type XIV. Tmem38b-/- showed a mild skeletal phenotype at the late larval and juvenile stages of development whereas tmem38bΔ120-7/Δ120-7 bone outcome was limited to a reduced vertebral length at 21 dpf. A caudal fin regeneration study pointed towards impaired activity of osteoblasts and osteoclasts associated with mineralization impairment.DiscussionOur data support the requirement of Tric-b during early development and for bone cell differentiation.
Evolution of non-thyroidal illness syndrome in acute decompensation of liver cirrhosis and acute-on-chronic liver failure
Authors: Langer Mona-May , Bauschen Alina , Guckenbiehl Sabrina , Klauss Sarah , Lutz Teresa , Denk Gerald , Zwanziger Denise , Moeller Lars C. , Lange Christian M. 
Published: January 2023

Background and aimsNon-thyroidal illness syndrome (NTIS) is frequent in critically ill patients and associated with adverse outcomes. We aimed to characterize the evolution of NTIS in patients with acute decompensation (AD) of cirrhosis and acute-on-chronic liver failure (ACLF), since NTIS is not well described in these newly defined syndromes.MethodsThyroid hormones (TH) were quantified at baseline in consecutive patients with cirrhosis. In addition, 76 inflammatory mediators were quantified by proximity extension analysis assay in a subgroup of patients. Associations between TH, cirrhosis stage, mortality and inflammation were assessed.ResultsOverall, 437 patients were included, of whom 165 (37.8%), 211 (48.3%), and 61 (14%) had compensated cirrhosis (CC), AD, and ACLF. FT3 concentrations were lower in AD versus CC, and further decreased in ACLF. Importantly, NTIS was present in 83 (39.3%) patients with AD and in 44 (72.1%) patients with ACLF (P&lt;0.001). Yet, TSH and TSH-based indexes (TSH/FT3-ratio, thyroid index) showed an U-shaped evolution during progression of cirrhosis, suggesting a partially preserved responsiveness of the hypothalamus and pituitary in AD. Infections were associated with lower FT3 concentrations in AD, but not in ACLF. Low FT3 concentrations correlated significantly with 90-day mortality. Both, AD/ACLF and NTIS, were associated with signatures of inflammatory mediators, which were partially non-overlapping.ConclusionNTIS is frequent already in AD and therefore precedes critically illness in a subgroup of patients with decompensated cirrhosis. This might constitute a new paradigm of TH signaling in cirrhosis, offering opportunities to explore preventive effects of TH in AD.