bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catalytic degradation of organic pollutant by biosynthesized silver nanoparticles using Trigonella foenum-graceum L. leaves
Authors: Moond Monika , Singh Sushila , Sangwan Seema , Devi Ritu , Beniwal Anuradha , Rani Jyoti , Beniwal Rajita , Sharma Rajni Kant 
Published: April 2023

Abstract
The usefulness of plant extracts in the green synthesis of silver nanoparticles (AgNPs) have received a lot of interest since it is easy, environmentally benign, stable and economical. The present study involves biosynthesis of AgNPs using Trigonella foenum-graceum L. leaf extract belonging to specific variety HM (Hisar Mukta) 425. The different reaction conditions such as amount of leaf extract, temperature, concentration of silver nitrate, pH and incubation period were optimized by using UV-Visible spectrophotometer. The average particle size, morphology and elemental composition of the AgNPs were studied through UV-Vis spectroscopy, Particle size analyser (PSA), Field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), High resolution transmission electron microscopy (HRTEM) and Fourier Transform Infrared Spectroscopy (FTIR). The average size of AgNPs was found to be 19 nm and were spherical in shape. The efficacy of AgNPs as a catalyst was confirmed by the 13 minutes completion of the organic pollutant p-nitrophenol (p-NP) reduction. Their catalytic capabilities strongly support the use of AgNPs in the purification of contaminated water.
The Effect of Comorbid Somatic Pain and Psychiatric Disorder on Oral Health-Related Quality of Life in Patients with Malocclusion
Authors: Xie Yaxin , Ye Shiyang , Li Yuanhong , He Jiayue , Han Xianglong 
Published: April 2023

Abstract
Background Malocclusion patients, as a population highly concerned with oral health-related quality of life (OHRQoL), are especially at risk of developing psychiatric disorders. Since somatic pains are frequently accompanied by psychiatric disorders, a growing body of research is starting to focus on this comorbidity in the orthodontic patient population. However, the relationships among somatic pains, psychiatric disorders, and impaired OHRQoL during orthodontic treatment remain unknown.Method In the current study, scale measurements including somatic pain (quantified by PHQ-15), mental disorders (quantified by HEI, PIDAQ, and SCL90), and OHRQoL (verified by OHIP-14) were collected from 769 outpatients in the orthodontic department. According to their reports of the presence or absence of somatic pain, respondents were divided into with symptoms and without symptoms groups. Variation analysis and correlation analysis were used to investigate the relationships among different clinical assessments. A chained mediation model was further conducted to explore the direct and indirect effects of these various clinical factors.Results The scores of HEI, SCL90, and OHIP-14 were significantly higher in the patients with somatic pain symptoms (P < 0.001). The higher PHQ-15-P and HEI scores remained as statistically significant predictors of lower OHIP-14 scores (P < 0.001). Anxiety and depression partially mediated the correlation between somatic pain and OHRQoL, of which the mediation effect of anxiety (52.9%) dominated the indirect effect.Conclusion Orthodontic Patients with somatic pain symptoms were at significantly higher risk for mental disorders and lower OHRQoL. Somatic pain can influence the orofacial system and was partially mediated by comorbid anxiety and depression. The comorbidity of somatic symptoms and psychological disorders influence the quality of life significantly and thus the prognosis of the orthodontic treatment.
Simulation of Chinese Language and Text Information System Processing Mode Based on Hidden Markov Model
Authors: Mengzhan Zhou 
Published: April 2023

Abstract
With the popularization of computers, artificial intelligence technology has become more and more mature, among which speech recognition technology in artificial intelligence is favored by people. In the past few years, the acoustic model combined with the Gaussian mixture model and the hidden Markov model has always been in the leading position. In the field of speech recognition technology, because the development of speech data has gradually expanded, and the complexity of the data has also increased. The larger the data, the traditional data network model is slowly showing inadequacy. However, the deep neural network model is easy to deal with large and complex data modeling. This article combines the advantages of basic learning theory and speech recognition technology, and launches in-depth research on embedding learning theoretical knowledge into the field of speech recognition. Nowadays, large-scale text information databases relying on computers are becoming more and more important in linguistic research, and a large-scale corpus that fully reflects language facts and contains rich language information has been constructed. The establishment of the text information database system is long, from word segmentation, part-of-speech tagging to syntactic tagging to semantic tagging. Therefore, the characteristic of information system processing is that the systematic description depends on the application environment of understanding vocabulary and reasoning. According to different scenarios, the realization methods of semantic description roles are also different, and the description of semantic roles in correct scenarios is clearer, more detailed and systematic. Therefore, this article is of great significance for solving the semantic problem of using Chinese frame network for Chinese information processing in the context of speech recognition.
Chest Circumference Predicts MAFLD Better than Waist Circumference and BMI in Obese Prepubertal Children Aged 8 Years
Authors: Zeng Jing , Jin Qian , Yang Jing , Yang Rui-Xu , Zhang Rui-Nan , Zhao Jian , Fan Jian-Gao 
Published: April 2023

Abstract
Backgroundand Aim
Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a new inclusive definition of the entire spectrum of liver diseases associated with metabolic disorders. This study aimed to determine the prevalence of MAFLD using controlled attenuation parameter (CAP) values obtained by transient elastography (TE) technique and identify the optimal predicator for diagnosing MAFLD in this population.
Methods
This study enrolled children who were part of the Shanghai Birth Cohort Study and had completed the 8-year-old follow-up. Anthropometric measurements were taken, and FibroScan-502 examination with an M probe (Echosens, Paris, France) was conducted on these children. The diagnosis of MAFLD was based on the median CAP exceeding 248 dB/m and predefined criteria. Receiver operating characteristic (ROC) curve analysis was performed to identify the optimal predicator for MAFLD in these children.
Results
A total of 848 healthy 8-year-old children (431 boys and 417 girls) who participated in the Shanghai Birth Cohort Study were included in the analysis. Among them, 113 (13.33%) children were classified as obese. The prevalence of obesity was significantly higher in boys (17.63%) than in girls (8.87%) (p < 0.001). The prevalence of central obesity was significantly higher in girls (34.05%) than in boys (22.04%) (p < 0.001). MAFLD was diagnosed in 29 (3.42%) children. The prevalence of MAFLD was significantly higher in the obese group (15.93%) than in the non-obese group (1.50%) (p < 0.05). Children with MAFLD had significantly higher weight, BMI, chest circumference, waist circumference, hip circumference, waist-to-height ratio, waist-to-hip ratio, and liver stiffness measurement than non-MAFLD (all p < 0.05). Waist circumference (OR: 1.187; 95%CI: 1.132-1.243; p < 0.001) was significantly associated with the presence of MAFLD in these participants in multivariate linear regression analyses. Chest circumference (OR: 1.321; 95%CI: 1.123-1.424; p < 0.001) was significantly associated with the presence of MAFLD in obese participants and had the largest AUC of 0.813 in ROC curve analysis.
Conclusion
This study highlights the prevalence of MAFLD in prepubertal children, particularly in the obese subgroup. Our findings also suggest that chest circumference is an optimal anthropometric predicator for MAFLD in 8-year-old obese children.
What to Expect from Primary Inferior Oblique Overaction After Esotropia Surgery
Authors: Freitas-da-Costa Paulo , Alves Hélio , Santos-Silva Renato , Falcão-Reis Fernando , Breda Jorge , Magalhães Augusto 
Published: April 2023

Abstract
Background Overelevation in adduction is a common feature of patients with primary esotropia. This study evaluates the variation in ocular motility pattern in patients with primary inferior oblique (IO) muscle overaction after esotropia surgery.Methods The medical records of consecutive patients who underwent surgery for infantile, partially accommodative, and basic esotropia over eleven years and had at least one year of follow-up were reviewed. Patients with primary inferior oblique muscle overaction (IOOA) presented at baseline or during follow-up were selected and divided according to the first surgery performed concurrently with horizontal rectus surgery: without IO recession (NO-recess), with unilateral IO recession (UNIL-recess), and with bilateral IO recession (BIL-recess). The success and recurrence rates and the evolution of the non-operated IO muscles were evaluated.Results One hundred and ten patients were included – 53 NO-recess, 26 UNIL-recess, and 31 BIL-recess. Medial rectus muscle posterior fixation sutures surgery (PFS) was performed in 88.2% of patients for esotropia. A recession with graded anterior transposition was the weakening IO procedure. In the NO-recess group, 28 (52.8%) patients normalized their mild IOOA after PFS surgery alone. In the UNI-recess group, 16 (61.5%) patients showed worsening of the fellow eye IO muscle, which prompted additional surgery in 10 patients. In the BIL-recess group, all 31 patients (100%, 62 eyes) improved the adduction pattern of the operated eye. The surgical success rate was 88.5% in the UNIL-recess group and 80.6% in the BIL-recess group.Conclusion Graded anterior transposition of the inferior oblique muscle effectively normalizes versions. However, it’s frequent for a contralateral overaction to become manifest after unilateral IO surgery.
Von – Willebrand Factor, a Possible Biomarker for Disease Activity in Vasculitis
Authors: Keret Shiri , Mazareeb Jomana , Snir Ayelet , Shouval Aniela , Awisat Abid , Kaly Lisa , Rosner Itzhak , Rozenbaum Michael , Boulman Nina , Hardak Emilia , Slobodin Gleb , Rimar Doron 
Published: April 2023

Abstract
Background: Inflammation markers commonly used to evaluate disease activity in vasculitis, C- reactive protein (CRP) and sedimentation rate, are often normal despite active disease. Von – Willebrand factor (vWF), is synthesized primarily in endothelial cells and secreted in response to vascular damage. Sporadic reports suggested increased vWF levels in vasculitis.Aim: To evaluate vWF serum concentration in patients with vasculitis as a marker of disease activity.Methods: Adult patients with systemic vasculitis were prospectively enrolled. Disease activity was recorded using the Birmingham Vasculitis Activity Score (BVAS) v3. Blood group adjusted vWF antigen serum level was evaluated at diagnosis and when available after treatment.Results: Twenty-five patients with systemic vasculitis were compared to 15 healthy controls. The mean age of patients was 56 ± 17 years and 56% were women. 40% had ANCA-associated vasculitis; 20% had giant cell arteritis; 16% had polyarteritis nodosa; 8% had Takayasu arteritis and the rest had other vasculitides. The mean disease duration was 3.4 ± 4.8 years. Mean vWF was higher in patients with active vasculitis compared to patients in remission or low disease activity state and healthy controls- 212%±81, 159%±80, and 106%±26, respectively. vWF levels directly correlated with BVAS. In 13 patients with active vasculitis who reached remission or LDA after treatment, vWF level at follow-up decreased significantly. In 3/5 patients who were treated with IL-6 inhibitors, vWF was elevated despite normal CRP levels, while clinically vasculitis was active.Conclusion: vWF Ag serum level is increased in active vasculitis and is suggested as a biomarker for disease activity.
Elliptic Quaternion and Elliptic linear Interpolation
Authors: Ghadami Raheleh , Yaylı Yusuf 
Published: April 2023

Abstract

On a sphere in Euclidean space, spherical spline quaternion interpolation has been carried out using quaternions. Using elliptic quaternions, we performed linear interpolation on an ellipsoid in this research. This interpolation curve is called Elerp elliptic linear interpolation. In addition, ESquad (spline elliptic quaternion interpolation) is defined by using the group structure feature of elliptic quaternion on ellipsoid.
Time-resolved FTIR Difference Spectroscopy for the Study of Photosystem I with High Potential Naphthoquinones Incorporated into the A 1 Binding Site. Identification of Neutral State Quinone Bands
Authors: Hastings Gary , Agarwala Neva 
Published: April 2023

Abstract
Time-resolved step-scan FTIR difference spectroscopy at 77 K has been used to study cyanobacterial photosystem I (PSI) from Synechocystis sp. PCC 6803 with four high-potential, 1,4–naphthoquinones (NQs) incorporated into the A1 binding site. The incorporated quinones are 2–chloro–NQ (2ClNQ), 2–bromo–NQ (2BrNQ), 2,3–dichloro–NQ (Cl2NQ), and 2,3–dibromo–NQ (Br2NQ). For completeness 2-methyl-NQ (2MNQ) was also incorporated and studied. Here we focus on spectra in the previously unexplored 1400 − 1200 cm− 1 spectral region. In this region several bands are identified and assigned to the neutral state of the incorporated quinones. This is important as identification of neutral state quinone bands in the regular 1700 − 1600 cm− 1 region has proven difficult in the past. For neutral PhQ in PSI a broad, intense band appears at ⁓1300 cm− 1. For the symmetric di-substituted NQs (Cl2NQ/Br2NQ) a single intense neutral state band is found at ~ 1280/1269 cm− 1, respectively. For both mono-substituted NQs, 2ClNQ and 2BrNQ, however, two neutral state bands are observed near 1280 and ⁓1250 cm− 1, respectively. These observations from time-resolved spectra agree well with conclusions drawn from absorption spectra of the NQs in THF, which are also presented here. Density functional theory (DFT) based vibrational frequency calculations are also undertaken allowing an identification of the normal modes associated with the neutral state quinone bands. Multiple types of double difference spectra are compared and it is shown that this comparison is a potent approach for band identification in highly convoluted spectra.
Persistent descending mesocolon as a vital risk factor for anastomotic failure and prolonged operative time for sigmoid colon and rectal cancers
Authors: Mei Shiwen , Zhang Mingguang , Ye Feng , Qiu Wenlong , Quan Jichuan , Zhuang Meng , Wang Xishan , Tang Jianqiang 
Published: April 2023

Abstract
Background The diagnostic criteria and effect of persistent descending mesocolon (PDM) on sigmoid and rectal cancers (SRCs) remain controversial. This study aims to clarify PDM patients' radiological features and short-term surgical results.
Method From January 2020 to December 2021, radiological imaging data from 845 consecutive patients were retrospectively analyzed using multiplanar reconstruction (MRP) and maximum intensity projection (MIP). PDM is deﬁned as the condition wherein the right margin of the descending colon is located medially to the left renal hilum; this is usually proved intraoperatively. The anatomical features and surgical results of PDM patients were compared with those of non-PDM patients.
Results The frequency of PDM was 3.8%. The lengths from the inferior mesenteric artery (IMA) to the inferior mesenteric vein (1.6 vs. 2.5 cm, p＜0.001), IMA to marginal artery arch (2.7 vs. 8.4 cm, p＜0.001), and IMA to the colon (3.5 vs. 9.8 cm, p＜0.001) were significantly shorter in the PDM group than those in the non-PDM group. The conversion to open surgery (12.5% vs. 1.2%, p=0.001), operative time (207.5 vs. 156 min, p=0.001), intraoperative blood loss (p＜0.001), marginal arch injury (15.6% vs. 1.1%, p＜0.001), splenic flexure free (21.9% vs. 3.3%, p＜0.001), and Hartmann procedure (15.6% vs. 0.1%, p＜0.001) were significantly higher in the PDM group. Moreover, PDM was an independent risk factor for prolonged operative time (OR=3.205, p=0.004) and anastomotic failure (OR=7.601, p=0.003).
Conclusion PDM was an independent risk factor for prolonged operative time and anastomotic failure in SRC surgery. Preoperative radiological evaluation using MRP and MIP can help surgeons better handle this rare congenital variant.
miR-22-3p regulates hepatocellular carcinoma invasion and proliferation through the Rap1/mTOR signaling pathway
Authors: Hao Yuesong , Su Huizhao , Wei Pingzhen , Li Yizheng , Cui Ping 
Published: April 2023

Abstract
Objective Liver cancer is a deadly cancer worldwide. As important biomarkers, miRNAs play important roles in different tumors but the mechanism of miRNAs in hepatocellular carcinoma is unclear. This study aims at exploring the regulatory function and mechanisms linked to miR-22-3p in hepatoma.Methods A proper miR-22-3p evaluation has been perfomed in hepatocellular carcinoma cells. Different assays evaluated cell migration, invasion and expansion, including the CCK8, colony formation and transwell ones. The dual luciferase reporter analysis explored how miR-22-3p and Rap1B were related together. A xenograft model in nude mice was also developed.Results Low miR-22-3p levels were poorly prognostic in patients with hepatoma. The miR-22-3p expression was downregulated in hepatocellular carcinoma tissues. In hepatocellular carcinoma cells, silencing miR-22-3p significantly favored cell expansion, migration and invasion, whereas miR22-3p overexpression determined opposite findings. The miR-22-3p bound to Rap1B 3’ UTR regulated the expression of Rap1B, thereby further activating its downstream signaling molecules.Conclusion In hepatocellular carcinoma, the miR-22-3p influenced cell expansion, invasion and migration through the novel target Rap1B and the mTOR pathway.
Adoption of Artificial Intelligence in the Ugandan Health Sector: a review of Literature
Authors: Mirugwe Alex 
Published: April 2023

Abstract
This paper presents a comprehensive literature review on the application of artificial intelligence techniques in Ugandan healthcare and the medical industry. Recently, the data generated in the health domain has exceeded the human cognitive capacity to analyze it effectively. Several approaches have been suggested to address this problem but in several studies, Artificial Intelligence has been found to be the best and the most effective solution as far as speed, accuracy, robustness, and reliability are concerned. We searched and reviewed AI health-related peer-reviewed articles in ScienceDirect, Springer, PubMed, arXiv, IEEE Xplore, medRxiv, PLOS, Wiley Online Library, BioMed Central, bioRxiv, and Scopus published between 2012 and 2022. This literature survey covered 38 research papers, and the review showed that the most applied AI subfields are statistical learning, machine learning, and deep learning. The paper highlights the challenges, gaps, and opportunities required to improve and advance the application of AI in the Ugandan healthcare industry. We believe this study will help researchers and policymakers to foster AI innovations better.
Does IFRS mandatory adoption promote economic growth in European countries via Cost of Capital: Pooled Mean Group-ARDL vs Generalized Method of Moments
Authors: GHOUMA Ghouma , BECHA Hamdi , KALAI Maha , HELALI Kamel 
Published: April 2023

Abstract

This study examines the effect of IFRS mandatory adoption on economic growth in 17 European countries via the Cost of Capital between 1994 and 2021 using PMG-ARDL and GMM-system techniques. The results show that IFRS adoption in European countries positively affects economic growth. This implies that the adoption of IFRS in these countries has led to improvements in financial reporting quality, which has positively impacted investment decisions and stimulated economic growth. These results provide insights into the benefits of adopting international accounting standards and highlight the importance of institutional and financial factors in shaping the economic impact of adopting accounting standards.
JEL Classification: C23; M40; O11; O52.
Metabolic pseudo-progression in a patient with metastatic KIT exon 11 GIST after one month of first-line imatinib: a case report
Authors: Tassinari Elisa , Conci Nicole , Battisti Giacomo , Porta Francesco , Scioscio Valerio Di , Pirini Maria Giulia , Nigro Maria Concetta , Iezza Miriam , Castagnetti Fausto , Lovato Luigi , Fanti Stefano , Pantaleo Maria Abbondanza , Margherita Nannini 
Published: April 2023

Abstract
Background Positron emission tomography (PET) with 18-fluorodeoxyglucose (18FDG) has proven to be highly sensitive in early assessment of tumor response in GIST, especially in cases where there is doubt, or when early prediction of the response could be clinically useful for patient management. As widely known, kinase mutations have an undoubtful predictive value for sensitivity to imatinib and the inclusion of KIT and PDGFRa mutational analysis in the diagnostic work-up of all GIST is now considered as standard practice.Case presentation Herein we detailed described a case of an exon 11 KIT mutated-metastatic GIST patient, who presented an unexpected metabolic progression at the early 18FDG-PET evaluation after one month of first line imatinib, unconfirmed at the liver biopsy performed near after, which has conversely shown a complete pathological response.Conclusions This report aims to be aware of the existence of this metabolic pseudoprogression in GIST at the beginning of imatinib therapy, in order to avoid early treatment discontinuation. Therefore, an early metabolic progression during a molecular-targeted therapy always deserves to be evaluated in the context of the disease molecular profiling and in case of discordant finding between functional imaging and molecular background, a short-term longitudinal control should be suggested.