bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Multitrajectories of Lipid Indices With Premature Cardiovascular Disease: A Cohort Study
Authors: Tian Xue , Chen Shuohua , Wang Penglian , Zhang Yijun , Zhang Xiaoli , Xu Qin , Wu Shouling , Wang Anxin 
Published: April 2023

Background
The multitrajectory model can identify joint longitudinal patterns of different lipids simultaneously, which might help better understand the heterogeneous risk of premature cardiovascular disease (CVD) and facilitate targeted prevention programs. This study aimed to investigate the associations between multitrajectories of lipids with premature CVD.

Methods and Results
The study enrolled 78 526 participants from the Kailuan study, a prospective cohort study in Tangshan, China. Five distinct multitrajectories of triglyceride, low‐density lipoprotein cholesterol (LDL‐C), and high‐density lipoprotein cholesterol over 6‐year exposure were identified on the basis of Nagin's criteria, using group‐based multitrajectory modeling. During a median follow‐up of 6.75 years (507 645.94 person‐years), 665 (0.85%) premature CVDs occurred. After adjustment for confounders, the highest risk of premature CVD was observed in group 4 (the highest and increasing triglyceride, optimal and decreasing LDL‐C, low and decreasing high‐density lipoprotein cholesterol) (hazard ratio [HR], 2.13 [95% CI, 1.36–3.32]), followed by group 5 (high and decreasing triglyceride, optimal and increasing LDL‐C, low and decreasing high‐density lipoprotein cholesterol) (HR, 2.07 [95% CI, 1.45–2.98]), and group 3 (optimal and increasing triglyceride, borderline high and increasing LDL‐C, optimal and decreasing high‐density lipoprotein cholesterol) (HR, 1.90 [95% CI, 1.32–2.73]).

Conclusions
Our results showed that the residual risk of premature CVD caused by increasing triglyceride levels remained high despite the fact that LDL‐C levels were optimal or declining over time. These findings emphasized the importance of assessing the joint longitudinal patterns of lipids and undertaking potential interventions on triglyceride lowering to reduce the residual risk of premature CVD, even among individuals with optimal LDL‐C levels.
BNT162b2 or CoronaVac Vaccinations Are Associated With a Lower Risk of Myocardial Infarction and Stroke After SARS‐CoV‐2 Infection Among Patients With Cardiovascular Disease
Authors: Ye Xuxiao , Yan Vincent K. C. , Yiu Hei Hang Edmund , Shami Jessica J. P. , Kang Wei , Ma Tiantian , Qin Xiwen , Chui Celine S. L. , Lai Francisco T. T. , Li Xue , Wan Eric Y. F. , Wong Carlos K. H. , Wong Ian C. K. , Chan Esther W. 
Published: April 2023

Background
COVID‐19 vaccines have demonstrated effectiveness against SARS‐CoV‐2 infection, hospitalization, and mortality. The association between vaccination and risk of cardiovascular complications shortly after SARS‐CoV‐2 infection among patients with cardiovascular disease remains unknown.

Methods and Results
A case–control study was conducted with cases defined as patients who had myocardial infarction or stroke within 28 days after SARS‐CoV‐2 infection between January 1, 2022 and August 15, 2022. Controls were defined as all other patients who attended any health services and were not cases. Individuals without history of cardiovascular disease were excluded. Each case was randomly matched with 10 controls according to sex, age, Charlson comorbidity index, and date of hospital admission. Adjusted odds ratio with 95% CI was estimated using conditional logistic regression. We identified 808 cases matched with 7771 controls among all patients with cardiovascular disease. Results showed that vaccination with BNT162b2 or CoronaVac was associated with a lower risk of myocardial infarction or stroke after SARS‐CoV‐2 infection with a dose–response relationship. For BNT162b2, risk decreased from 0.49 (95% CI, 0.29–0.84) to 0.30 (95% CI, 0.20–0.44) and 0.17 (95% CI, 0.08–0.34) from 1 to 3 doses, respectively. Similar trends were observed for CoronaVac, with risk decreased from 0.69 (95% CI, 0.57–0.85) to 0.42 (95% CI, 0.34–0.52) and 0.32 (95% CI, 0.21–0.49) from 1 to 3 doses, respectively.

Conclusions
Vaccination with BNT162b2 or CoronaVac is associated with a lower risk of myocardial infarction or stroke after SARS‐CoV‐2 infection among patients with cardiovascular disease.
Catestatin Protects Against Diastolic Dysfunction by Attenuating Mitochondrial Reactive Oxygen Species Generation
Authors: Qiu Zeping , Fan Yingze , Wang Zhiyan , Huang Fanyi , Li Zhuojin , Sun Zhihong , Hua Sha , Jin Wei , Chen Yanjia 
Published: April 2023

Background
Catestatin has been reported as a pleiotropic cardioprotective peptide. Heart failure with preserved ejection fraction (HFpEF) was considered a heterogeneous syndrome with a complex cause. We sought to investigate the role of catestatin in HFpEF and diastolic dysfunction.

METHODS AND RESULTS
Administration of recombinant catestatin (1.5 mg/kg/d) improved diastolic dysfunction and left ventricular chamber stiffness in transverse aortic constriction mice with deoxycorticosterone acetate pellet implantation, as reflected by Doppler tissue imaging and pressure‐volume loop catheter. Less cardiac hypertrophy and myocardial fibrosis was observed, and transcriptomic analysis revealed downregulation of mitochondrial electron transport chain components after catestatin treatment. Catestatin reversed mitochondrial structural and respiratory chain component abnormality, decreased mitochondrial proton leak, and reactive oxygen species generation in myocardium. Excessive oxidative stress induced by Ru360 abolished catestatin treatment effects on HFpEF‐like cardiomyocytes in vitro, indicating the beneficial role of catestatin in HFpEF as a mitochondrial ETC modulator. The serum concentration of catestatin was tested among 81 patients with HFpEF and 76 non–heart failure controls. Compared with control subjects, serum catestatin concentration was higher in patients with HFpEF and positively correlated with E velocity to mitral annular e′ velocity ratio, indicating a feedback compensation role of catestatin in HFpEF.

Conclusions
Catestatin protects against diastolic dysfunction in HFpEF through attenuating mitochondrial electron transport chain–derived reactive oxygen species generation. Serum catestatin concentration is elevated in patients with HFpEF, probably as a relatively insufficient but self‐compensatory mechanism.
Cardiovascular Magnetic Resonance in Survivors of Critical Illness: Cardiac Abnormalities Are Associated With Acute Kidney Injury
Authors: Isaak Alexander , Pomareda Isabel , Mesropyan Narine , Kravchenko Dmitrij , Endler Christoph , Bischoff Leon , Pieper Claus C. , Kuetting Daniel , Attenberger Ulrike , Zimmer Sebastian , Putensen Christian , Schewe Jens‐Christian , Kreyer Stefan , Luetkens Julian A. 
Published: April 2023

Background
The objective of this study was to investigate cardiac abnormalities in intensive care unit (ICU) survivors of critical illness and to determine whether temporary acute kidney injury (AKI) is associated with more pronounced findings on cardiovascular magnetic resonance.

Methods and Results

There were 2175 patients treated in the ICU (from 2015 until 2021) due to critical illness who were screened for study eligibility. Post‐ICU patients without known cardiac disease were prospectively recruited from March 2021 to May 2022. Participants underwent cardiovascular magnetic resonance including assessment of cardiac function, myocardial edema, late gadolinium enhancement, and mapping including extracellular volume fraction. Student
t
test, Mann‐Whitney
U
test, and χ
2
tests were used. There were 48 ICU survivors (46±15 years of age, 28 men, 29 with AKI and continuous kidney replacement therapy, and 19 without AKI) and 20 healthy controls who were included. ICU survivors had elevated markers of myocardial fibrosis (T1: 995±31 ms versus 957±21 ms,
P
<0.001; extracellular volume fraction: 24.9±2.5% versus 22.8±1.2%,
P
<0.001; late gadolinium enhancement: 1% [0%–3%] versus 0% [0%–0%],
P
<0.001), more frequent focal late gadolinium enhancement lesions (21% versus 0%,
P
=0.03), and an impaired left ventricular function (eg, ejection fraction: 57±6% versus 60±5%,
P
=0.03; systolic longitudinal strain: 20.3±3.7% versus 23.1±3.5%,
P
=0.004) compared with healthy controls. ICU survivors with AKI had higher myocardial T1 (1002±33 ms versus 983±21 ms;
P
=0.046) and extracellular volume fraction values (25.6±2.6% versus 23.9±1.9%;
P
=0.02) compared with participants without AKI.

Conclusions
ICU survivors of critical illness without previously diagnosed cardiac disease had distinct abnormalities on cardiovascular magnetic resonance including signs of myocardial fibrosis and systolic dysfunction. Findings were more abnormal in participants who experienced AKI with necessity of continuous kidney replacement therapy during their ICU stay.

Registration

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT 05034588.
Ethogram for blacktip reef sharks (Carcharhinus melanopterus)
Authors: Porcher Ila F. 
Published: April 2023

Abstract
The chondrichthyan lineage diverged from the osteichthyan line around 440 million years ago, resulting in a vast evolutionary gulf between modern elasmobranchs and other vertebrates. Though this has supported the assumption that as an ancient line, elasmobranchs are dangerously stupid, intelligent actions including social interactions have been noted in the field, while laboratory studies have confirmed a variety of cognitive capacities. Yet, due to fear of sharks and the difficulties of observing them in their aquatic environments, few ethological studies have been done, so their natural behaviour remains little known. On noting that the blacktip reef shark, Carcharhinus melanopterus, displayed complex actions during incidental meetings, a long-term ethological study of the species was carried out on the north shore of Mo’orea Island, French Polynesia. During the 6.5 years of the study, new behaviours continued to present. The 35 context-specific actions identified as comprising the behavioural repertoire of C. melanopterus are described.
A new species of Acanthocyclops Kiefer, 1927 (Copepoda, Cyclopoida) from ephemeral and permanent waterbodies of Sian Ka’an and Calakmul biosphere reserves, Mexico
Authors: Mercado-Salas Nancy F. , Suárez-Morales Eduardo , Khodami Sahar , Martínez Arbizu Pedro 
Published: April 2023

Abstract
A new species of the genus Acanthocyclops is described from temporal freshwater bodies in the Sian Ka’an and Calakmul Biosphere Reserves in Southeast Mexico. Acanthocyclops fiersi n. sp. represents the third species of the genus described from the Neotropics, only after A. rebecae and A. smithae. Acanthocyclops fiersi n. sp., is recognized as a member of the A. vernalis-robustus species-complex, and its clear divergence with respect to its congeners was supported using comparative morphology and molecular methods. The mtCOI marker revealed a 0.54% K2P divergence within populations of A. fiersi n. sp. and 17.6-22.41% with respect to other members of the A. vernalis-robustus species-complex. Acanthocyclops fiersi n. sp. might be restricted to the Yucatán Peninsula. Comments about the likely underestimated regional diversity of Acanthocyclops and the need of further studies in the Neotropics are provided. An identification key to the species of Acanthocyclops distributed in Mexico is included.
Fishery and population characteristics of the Indian white shrimp, Penaeus indicus H. Milne Edwards, 1837 (Decapoda, Dendrobranchiata) in Pulicat Lake, southeast coast of India
Authors: Jesintha N. , Jayakumar N. , Madhavi K. , Karuppasamy K. 
Published: April 2023

Abstract
Fishery and population characteristics of the Indian white shrimp, Penaeus indicus, were studied in Pulicat Lake, on the southeast coast of India, using the FiSAT software package. The asymptotic length (), growth coefficient (K) and arbitrary origin of growth (t0) were estimated by the ELEFAN method to be 16.18 cm, 0.60 year−1 and −0.18 year, respectively. The asymptotic length () was calculated as 16.09 cm using the Wetherall method. The growth performance index (Ø′) was found to be 2.19. The mortality parameters Z, F and M were computed to be 3.85, 2.30 and 1.55 year−1, respectively. The pattern of recruitment was observed to be year-round, with a peak from June to September. The total stock, annual catch and exploitation rate for P. indicus were estimated to be 1518.43 tonnes, 809.3 tonnes, and 0.59 year−1, respectively. The estimated Maximum Sustainable Yield (MSY) was found to be 131.95 tonnes less than the annual catch. The stock of P. indicus was found to be over-exploited, so it is suggested that the effort level be reduced by 16.3% in order to sustain this resource in Pulicat Lake.
Varieties of Unionism?
Authors: Nishida Naoki 
Published: April 2023

Abstract
Scholarly evidence on the causes of state-run unemployment insurance development is sometimes contradictory and disconnected, preventing our understanding of union-run unemployment insurance development. A set-theoretic approach based on Qualitative Comparative Analysis (QCA) can model the business–labor interaction in the development of union unemployment funds, revealing two paths by comparing 11 sectors in 20th-century France. In skill-intensive, low-risk firms, union funds developed only when unionization rates were low. In small, low-risk factories, funds developed regardless of workers’ wages. The sociability fostered by small unions and factories allowed for social control, reducing psychological barriers to insurance scheme establishment. By comparing the business–labor combinations in different industries, this study demonstrates the “variety of unionism” hidden beneath the existing macro cross-national evidence.
Does Changing an Electoral System to a Mixed System (Really) Affect Voter Turnout and the Party System?
Authors: Högström John , Dahlberg Stefan 
Published: April 2023

Abstract
In this study the authors aim to add to the understanding of whether, and if so how, a change of electoral system affects factors such as voter turnout and the party system, and the authors’ focus has been on changes that result in mixed electoral systems. They used three country cases (Japan, Italy, and New Zealand) to explore patterns in a before-and-after design. The findings suggest that a country cannot expect a significant effect on voter turnout if it decides to change its electoral system to a mixed system. Regarding party system fragmentation, the results show that the change of the electoral system in New Zealand from a plurality system to a mixed member proportional system had a clear and immediately positive effect on the party system. However, the results do not indicate that the changes of electoral systems in Japan and Italy have had any significant effect on the party system.
The Processes and Problems of Social Integration of Refugees in Greece in the 21st Century
Authors: Vlassopoulos Ioannis 
Published: April 2023

Abstract
Refugee populations constitute a new reality for Greek society. These moving populations contribute to a process of redefining social and cultural status in the countries of reception. The following article was written as part of the author’s PhD thesis. The research method used is that of qualitative research through semi-structured in-depth interviews with refugees and asylum seekers. The article refers to part of field research results that focus on the forms of social integration adopted by refugees and asylum seekers in Greece, as well as how integration or exclusion is perceived by the latter. The aim of this research is to portray the experiences of the refugees on the process of their social integration into Greece.
Comparison of the ecological niche of two closely related toads (Bufo bufo and Bufo verrucosissimus)
Authors: Gül Serkan , Dursun Cantekin , Kutrup Bilal , Üzüm Nazan , Özdemir Nurhayat 
Published: April 2023

Abstract
Understanding climatic variables to determine the ecological niche is crucial to explaining species distributions and revealing how sister species coexist within a geographic area. Here, we used ecological niche modeling to determine the ecological niche patterns of two toad species in Türkiye: Bufo bufo and Bufo verrucosissimus. Thus, we tested the ecological niche divergence and similarity between these species. In our results, the potential distribution of B. verrucosissimus showed high suitability throughout all Caucasus hotspots, and this suitability has been found even along the middle and western coast of Türkiye, but suitability was found to be very weak in the southern part of Türkiye. For B. bufo, the distribution pattern indicated high suitability along the Black Sea and Mediterranean coasts of Türkiye, but this suitability was low throughout Caucasus hotspots. Furthermore, we found that among B. bufo and B. verrucosissimus, the niches are not identical, but this situation is different in the background test. Therefore, we suggested that although there is niche conservatism between the two sister species, this pattern is caused by geographic barriers, not climatic parameters.
Aristotle’s Understanding of Democratic Justice and His Distinction between Two Kinds of Equality: A Response
Authors: Knoll Manuel 
Published: April 2023

Abstract
This short article is a response to Douglas Cairns, Mirko Canevaro, and Kleanthis Mantzouranis, who in Polis 39 (2022) explicitly criticize both of my previous interpretations of Aristotle’s view of democratic justice and of the relation of proportional and numerical equality. Against Cairns et al., I argue that there is no tension or contradiction between Aristotle’s statements on these two kinds of equality and on democratic justice. The paper suggests a new reading of Aristotle’s texts that strictly distinguishes between Aristotle’s own views and his references to ‘respected opinions’ (endoxa). It concludes that Aristotle consistently identifies democratic justice with ‘numerical’ or ‘arithmetic’ equality and not with proportional equality, which he usually identifies with equality ‘according to worth or merit’ (kat’ axian).
‘What’s in a Name?’ Ideology and Language in the Epistulae ad Caesarem
Authors: Paleo-Paz Héctor 
Published: April 2023

Abstract
The following paper offers a study on how contestation over the meaning of language forged the political ideology present in the second of the Epistulae ad Caesarem. ‘Ideology’ being a notoriously malleable concept, Michael Freeden’s theoretical approach is used to focus what it means, how it is manifested in the sources, and how it can be located and analysed. The political thought of the Late Republic is studied by examining the vocabulary contained in one of the disputed letters that Sallust addressed to Julius Caesar. Taking libertas as a case study of an ‘essentially contested concept’, the relation between language, meaning and ideology is dissected, outlining the morphological configuration that underlies the second Epistula. It is argued that the resulting array of political arguments is one iteration of what has been called popularis ideology.
The Model of Voting in Cicero’s Best State
Authors: McConnell Sean 
Published: April 2023

Abstract
In the proposed law-code in De legibus there is a law that votes are to be known by the best citizens (the optimates) but free to the common people (the plebs) (3.10). This law, Cicero claims, grants ‘the appearance of liberty’ (libertatis species), preserves the authority (auctoritas) of the optimates, and promotes harmony between the classes (3.39). The law and the precise meaning of libertatis species remain opaque even with the lengthy commentary (3.33–39), and much scholarly debate and discussion has arisen as a result – most of it very critical of Cicero’s proposal and the arguments supporting it. This paper offers a fresh analysis of the voting law that is more charitable to Cicero. It unpacks the full details of the voting system that is developed in De legibus and sheds new light on developments in Cicero’s thinking about the best state.
New Holocene Radiocarbon Dates from the Heart of the Sangha River Interval, Southwestern Central African Republic
Authors: Schmitt Dave N. , Lupo Karen D. , Amaye Guy T. , Ndanga Jean-Paul , Nguerede Lucien P. , Zana Henri 
Published: April 2023

Abstract
Radiocarbon assay of charcoal from four sites in Nola, Central African Republic, provide new age estimates from the Sangha River Interval and doubles the number of radiocarbon dates from the center of this important and controversial biogeographical tract. The new age estimates mark the occupation of a village ~575 cal BP, two iron-smelting events about 1550 cal BP, and a ~2750–2520 cal BP iron production feature that represents one of the earliest smelting sites in the Congo Basin. Although the numbers of dated sites in the northcentral Sangha River Interval remain unfortunately small, most represent iron production loci that predate 1550 cal BP and suggest Nola supported widespread Early Iron Age smelting on the cusp of a proposed human population collapse. The extant record also indicates this profusion of smelting occurred hundreds of years before intensification in metallurgy in the neighboring Lobaye River basin.
Classifying “Lao” Ethnic Languages Spoken in Central Thailand Using Tonal Criteria: A Case Study of “Chachoengsao Lao”
Authors: Pornpottanamas Warunsiri 
Published: April 2023

Abstract
In the linguistic literature on the languages of ethnic Lao in Thailand, labels such as “Lao” or “Lao Wiang” are often used to identify local dialects as Lao varieties. This study examines patterns of tonal splits and mergers in the linguistic varieties spoken by the so-called “Lao” ethnic groups in Chachoengsao Province, Thailand, to re-identify and reclassify the so called “Lao” languages collected from 124 participants at 50 locations. This study used the tone box concept (Gedney 1972) as a basic tool to analyse tonal patterns. The results indicate that the “Lao” ethnic languages of Chachoengsao can be classified into three main groups, namely Lao, Phuan and Hua Phan Tai Nuea. While the Lao varieties show typical tonal patterns of Lao dialects (B≠DL, C1=DL123 and/or C234=DL4), the other two groups show none of the patterns. The findings show that the patterns of tonal development labels are better criteria than ethnic labels in the identification of Lao groups.
“Dream Boy” and “Hotmale”
Authors: Lucido Santos Joey Andrew , Saisuwan Pavadee 
Published: April 2023

Abstract
Gender and sexuality have gradually become the focus of more semiotic landscape research, however, studies relating specifically to sex tourism spaces are limited and with those in the Thai context even more so. Therefore, this paper examines the discursive construction of Phatphong 2, one of the famous destinations for sex tourism in Bangkok among male homosexuals, as queer space. Drawing on code preference and inscription (Scollon and Scollon 2003) and visual social semiotics (Kress and Van Leeuwen 1996), we analyze the linguistic and semiotic resources in sexed signs. Findings reveal that Englishization, particularly the terms “boy” and “Bangkok” in shop signs, creates a glocalized and international queer identity for Phatphong 2. The salience of the lean male muscular body and marginalization of transwomen in promotional signs unveil the hegemonic masculinity in queer sex tourism spaces. The study concludes that sexed signs in sex tourism spaces are semiotic aggregates of global queer culture.