bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconfiguring Priorities: Breastfeeding Decision-making Among Young Breast Cancer Survivors
Authors: Huertas-Zurriaga Ariadna , Cabrera-Jaime Sandra , Navarri Isabel , Teruel-Garcia Iris , Leyva-Moral Juan Manuel 
Published: January 2025

Background
Breast cancer survivors face unique challenges in breastfeeding decisions. Limited research exists on the experiences and decision-making processes of young women with breast cancer regarding breastfeeding.

Objective
To explain the decision-making processes of young women with breast cancer in relation to breastfeeding throughout the cancer trajectory.

Methods
A constructivist grounded theory approach was used. Semistructured interviews were conducted with 12 women diagnosed with breast cancer and 8 healthcare professionals. Data were analyzed using constant comparative analysis.

Results
The core category “Reconfiguring Priorities: The Secondary Role of Breastfeeding in the Context of Breast Cancer in Young Women” emerged, encompassing 3 subcategories: (1) scars over time, (2) omitting breastfeeding in oncological care, and (3) self-management of breastfeeding.

Conclusions
Breastfeeding decision-making among young breast cancer survivors is not driven by conscious will but by a constant struggle with the conditioning factors of the oncological process: mortality and toxicity of drugs to breast milk. The lack of professional support leads women to develop their own strategies for managing breastfeeding, marked by ambivalence between motivations and personal challenges.

Implications for Practice
Healthcare professionals should integrate breastfeeding discussions into oncological care for young breast cancer survivors. Specialized lactation consultants with oncology expertise should be incorporated into the care team. Peer support programs can provide valuable guidance based on lived experiences, empowering women to make informed decisions about breastfeeding after breast cancer.
Development and Effects of a Smartphone Application to Improve Self-Management in Workers Who Underwent Thyroid Cancer Surgery
Authors: Kim Myoyoun , Hwang Seon Young 
Published: January 2025

Background
Although the survival rate for thyroid cancer is high, a nursing intervention that enhances autonomous motivation is needed for patients with jobs to improve their long-term self-management abilities in the early postoperative period.

Objectives
This study aims to develop a mobile application (app) based on the Self-Determination Theory for patients returning to work after thyroid cancer surgery and to verify its effectiveness.

Methods
We developed an app to promote self-management and verify its effectiveness after 12 weeks in early outpatients who underwent thyroid cancer surgery through a randomized controlled trial design. In addition to a subjective questionnaire, objective data on steps, stress, and sleep quality from a smartwatch are analyzed.

Results
Autonomous motivation (t = −2.11, P = .040), perceived health status (t = −2.05, P = .048), and perceived stress (t = 2.18, P = .039) show significant differences in the experimental group compared to the control group. Objective data collected using a smartwatch show that stress scores (t = 5.43, P = .006) and sleep quality scores (t = 3.83, P = .025) in the experimental group are significantly improved compared to those in the control group.

Conclusion
Among workers in the early stages after thyroid cancer surgery, using the smartphone app strengthens autonomous motivation and improves steps, stress levels, and sleep quality, making it an effective nursing intervention for self-management.

Implications for Practice
In outpatient nursing practice, self-management should be promoted using a smartphone app among adult patients returning to work soon after thyroid cancer surgery.
Neonatal and Home-Based PT Improves Neurodevelopmental Outcomes of Preterm Infants—A Randomized Clinical Trial
Authors: Khurana Sonia , Lewis Leslie E. , Russell Daniel M. , Dusing Stacey C. , Krishna Rao Bhamini 
Published: January 2025

Purpose:
Investigate the effect of structured neonatal physical therapy program (SNP) on neurodevelopmental outcomes of moderate and late preterm (MLP) infants.

Methods:
Sixty MLP infants were randomly allocated to usual care (UC) or SNP. A previous publication reported the effect of neonatal component of SNP at hospital discharge. This paper examined SNP’s effect on motor, cognitive and language outcomes at 3 and 6 months using a 2-way mixed design ANOVA.

Results:
Both groups were similar at baseline for motor scores. Infants receiving SNP significantly outperformed UC at all subsequent time points. At 3 and 6 months, SNP significantly outscored UC in cognitive and language outcomes.

Conclusion:
SNP is effective in improving neurodevelopmental outcomes of MLP infants. However, caution is suggested in interpreting its effect on cognition and language as we lacked baseline scores to compare the longitudinal trajectory.
Medical Student Confidence in Meeting Disability Competencies: Results of a national survey-based study
Authors: Clarke Lauren , Dhanani Zainub , Tan Louis , Altamirano Jonathan , Fassiotto Magali , Poullos Peter 
Published: January 2025

Abstract
People with disabilities have recently been declared a population at increased risk of health disparities, and research has cited a lack of physician training as a cause of that increased risk. Prior studies demonstrate that physicians lack confidence in caring for people with disabilities, but there is little research on disability competency among medical students. This study assessed medical students’ confidence in six disability-related competencies and tested for associations between perceived confidence and students’ personal demographics and institutional characteristics. A cross-sectional survey was administered to measure student confidence, and students’ perceived confidence was calculated using a 5-point Likert scale. Mean confidence ranged from 2.35 – 3.43, suggesting that most students felt either “slightly confident” or “somewhat confident” in their ability to meet the selected competencies. Confidence did not differ based on disability exposure or level of training; however, there was a significant positive relationship between attending a public (state) medical school and students’ confidence in listing community-based services for people with disabilities. This study highlights that future physicians are not confident in their ability to meet the needs of people with disabilities. Additional training is needed to teach future physicians the skills necessary to provide this population with high-quality clinical care.
Plasma microRNA Levels After Electroconvulsive Therapy in Treatment-Resistant Depressed Patients
Authors: Galbiati Chiara , Dattilo Vincenzo , Bortolomasi Marco , Vitali Erika , Abate Maria , Menesello Valentina , Meattini Mattia , Carvalho Silva Rosana , Gennarelli Massimo , Bocchio Chiavetto Luisella , Minelli Alessandra 
Published: January 2025

Objectives
Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-resistant depression (TRD), even though the molecular mechanisms underlying its efficacy remain largely unclear. This study aimed, for the first time, to analyze plasma levels of miRNAs, key regulators of gene expression, in TRD patients undergoing ECT to investigate potential changes during treatment and their associations with symptom improvement.

Methods
The study involved 27 TRD patients who underwent ECT. Plasma samples were collected at baseline (T0) and 1 month after the last ECT session (T1), and miRNA analysis was conducted by qRT-PCR. We also performed gene prediction of miRNAs differentially expressed and KEGG pathway analysis.

Results
miR-95-3p, miR-194-5p, miR-324-3p, miR-195-5p, miR-19b-3p, miR-30c-5p, let-7i-5p, and miR-497-5p were nominally downregulated at T1. Changes in miR-324-3p and miR-30c-5p levels between T0 and T1 significantly correlated with symptom improvement. Among the predicted miRNA target genes of these 2 miRNAs, we noticed the presence of VEGF and SIRT1, whose expression regulation has been associated with the ECT mechanism of action in previous studies.

Conclusions
The study's most relevant results are related to the correlation between reductions in miR-30c-5p and miR-324-3p and the improvement of symptoms in response to ECT, positioning these miRNAs as promising candidates for further studies. These findings support and extend previous clinical and preclinical research indicating a role of miRNAs in ECT mechanism of action. However, no significant effects in ECT miRNA modulation were observed, highlighting the need for future replications in broader samples to confirm these results.
Pseudomonas spirodelae, sp. nov., a bacterium isolated from the roots of the aquatic plant Spirodela polyrhiza
Authors: Vandeborne Karlie , Guy Nathan , Lengyel George , Franks Jonathan , Maltman Chris 
Published: January 2025

A polyphasic taxonomic study was carried out on strain T5W1T, isolated from the roots of the aquatic plant Spirodela polyrhiza. This isolate is Gram-negative, rod-shaped, motile, aerobic and non-pigmented. Nearly complete 16S rRNA gene sequence homology related the strain to Pseudomonas, with 98.4% similarity to P. guineae, P. peli and P. leptonychotis. Average nucleotide identity (ANI) and digital DNA–DNA hybridization (dDDH) with the closest phylogenetic neighbour of T5W1T showed differences at the species level, further confirmed by differences in several physiological characteristics. The main fatty acids are summed feature 3 (C16 : 1

ω7c and/or C16 : 1

ω6c), C18 : 1

ω7c, and C16 : 0. The DNA G+C content is 59.3 mol%. Q-9 is the primary ubiquinone found, and phosphatidylethanolamine is the dominant polar lipid, with lesser amounts of phosphatidylglycerol, diphosphatidylglycerol and phosphatidylserine. Based on the results obtained, this bacterium is assigned to the genus Pseudomonas as a new species with the name Pseudomonas spirodelae sp. nov., type strain T5W1T (=NRRL B-65714T =DSM 118085T).
Revealing hidden knowledge in amnestic mice
Authors: Santi Andrea , Moore Sharlen , Fogelson Kelly A. , Wang Aaron , Lawlor Jennifer , Amato Jordan , Burke Kali , Lauer Amanda M. , Kuchibhotla Kishore V. 
Published: January 2025

AbstractAlzheimer’s disease (AD) is a form of dementia in which memory and cognitive decline is thought to arise from underlying neurodegeneration. These cognitive impairments, however, are transient when they first appear and can fluctuate across disease progression. Here, we investigate the neural mechanisms underlying fluctuations of performance in amnestic mice. We trained APP/PS1+ mice on an auditory go/no-go task that dissociated learning of task contingencies (knowledge) from its more variable expression under reinforcement (performance). APP/PS1+ exhibited significant performance deficits compared to control mice. Using large-scale two-photon imaging of 6,216 excitatory neurons in 8 mice, we found that auditory cortical networks were more suppressed, less selective to the sensory cues, and exhibited aberrant higher-order encoding of reward prediction compared to control mice. A small sub-population of neurons, however, displayed the opposite phenotype, reflecting a potential compensatory mechanism. Volumetric analysis demonstrated that deficits were concentrated near Aβ plaques. Strikingly, we found that these cortical deficits were reversed almost instantaneously on probe (non-reinforced) trials when APP/PS1+ performed as well as control mice, providing neural evidence for intact stimulus-action knowledge despite variable ongoing performance. A biologically-plausible reinforcement learning model recapitulated these results and showed that synaptic weights from sensory-to-decision neurons were preserved (i.e. intact stimulus-action knowledge) despite poor performance that was due to inadequate contextual scaling (i.e. impaired performance). Our results suggest that the amnestic phenotype is transient, contextual, and endogenously reversible, with the underlying neural circuits retaining the underlying stimulus-action associations. Thus, memory deficits commonly observed in amnestic mouse models, and potentially at early stages of dementia in humans, relate more to contextual drivers of performance rather than degeneration of the underlying memory traces.
Ag+-regulated aptamers to thrombin
Authors: Alieva Rugiya , Sokolova Svetlana , Oleynikov Ilya , Novikov Roman , Zatsepin Timofei , Aralov Andrey , Zavyalova Elena 
Published: January 2025

AbstractNucleic acid aptamers are artificial recognition elements with high potential in biotechnology. Approaches for aptamer affinity optimization and activity regulation are required for aptamer-based nanodevices. Here thrombin aptamer affinity was increased by a single nucleotide modification with 7,8-dihydro-8-oxo-1,N6-ethenoadenine. Whereas a double modification makes the aptamer activity Ag+-dependent.
Bacteroidales T6SS minor Hcp subunits form heteromers recognising effectors
Authors: San-Miguel Sergio G. , Al-Ammari Manal Kamal Saleh , Kowalska Anna , Sauer Uwe , Batista Paulo Ricardo , Sandblad Linda , Uhlin Bernt Eric , Cisneros David A. 
Published: January 2025

AbstractThe type VI secretion system (T6SS) is a macromolecular protein complex found in Gram-negative bacteria that mediates intercellular antagonism and gut Bacteroidales use this system to increase their competitiveness. Furthermore, T6SS is a recognized gut colonization factor that influences gut biodiversity. Bacteroidales T6SSs are divergent from their well-characterized Pseudomonadota counterparts. One conserved feature in many Bacteroidales T6SSs is the presence of multiple Hcp proteins with low sequence similarity, encoded within the secretion system’s locus and adjacent to variable effector cassettes. Here we provide evidence that in the Bacteroides fragilis T6SS, these Hcp subunits, similar to other protein export systems function as high and low abundance major and minor subunits. First, we showed that these minor Hcp proteins form a network of interactions. Biochemical characterization of one of the minor Hcp complexes formed between Hcp1 and Hcp2 showed that they form hetero-hexamers with variable stoichiometry. Furthermore, we showed that this complex recognizes the secreted effector Bte1. Our results suggest that these minor subunits function as recognition particles for effectors to mediate secretion and that this is a conserved feature in Bacteroidales T6SS. The functionality of these Hcp-effector modules is encoded in a high-synteny region within T6SS loci, and bioinformatic analyses imply that this arrangement participates in establishing effector variability. Exploiting this feature could pave the way for characterizing numerous Bacteroidales effectors with unknown functions through copurification with their cognate Hcps, unlocking new insights into bacterial interactions and into mechanisms of gut biodiversity establishment.
Deep learning-based detection of players and teams in soccer videos with positioning heatmap generation
Authors: Tanapatpiboon Atitep , Kusakunniran Worapan , Limroongreungrat Weerawat 
Published: January 2025

PurposeThis paper uses computer vision to develop a method for collecting football players’ positions during a match. It also compares the differences between various solutions of the existing object detection models to determine discerning differences. Then, an illustration of the obtained information is created as a heatmap.Design/methodology/approachThe proposed method utilizes a dataset of side-view football broadcast footage to detect the players’ positions on the football at any given moment of the football match. Using YOLO object detection, the players of each team are identified and recorded to create valuable illustrations that the coaches can further analyze, training staff, etc. Using three different implementations of YOLO (YOLOv5m6, YOLOv5l-tph and YOLOv5l-tph-plus) the results will be compared to find out the best implementation for this specific task.FindingsAfter each YOLO implementation was trained using the same dataset, the results showed that YOLOv5l-tph performed best, achieving a precision of 0.9868. Meanwhile, YOLOv5l-tph-plus placed second, with a precision of 0.9786. Finally, YOLOv5m6 performed worst, with a precision of 0.8214.Originality/valueIn sports, various analytical information can be extracted from games, whether from statistical records or recorded footage. For “sports analytics,” the goal is to provide valuable insights that are otherwise not obtainable through traditional means, such as merely rewatching past footage. In both the past and the present, there have been multiple attempts at using statistical records to predict or quantify various aspects of the games.
Does shared prosperity affect perceived financial well-being among individual consumers?
Authors: Nga Joyce Koe Hwee , Kesumo Aristo 
Published: January 2025

PurposeThe purpose of this study is to investigate the relationship between shared prosperity and financial well-being from the individual grassroot perspective in Malaysia through the mediating influence of technological empowerment and responsible citizenship. The study also incorporates the effects of political stability on developmental policies such as shared prosperity as well as behavioural mindset change on financial well-being.Design/methodology/approachThis study employed the quantitative survey method using convenience sampling selected based on ethnicity and income levels. The questionnaire was developed for this study based on extant literature and the Malaysian Shared Prosperity Vision 2030 (SPV2030) policy document. The instrument was validated and data was then analysed using the Structural Equation Modelling approach.FindingsThe findings suggest that technological empowerment and responsible citizenship serve as mediators in ensuring that shared prosperity translates into financial well-being. Additionally, political stability and behavioural mindset are crucial in supporting SPV2030 and financial well-being, respectively.Research limitations/implicationsThe study highlights the need for political awareness and education, as well as the importance of revising legacy policies and enhancing policy feedback mechanisms to support financial well-being.Practical implicationsThis study suggests that individuals need to shift their mindset to create opportunities and take risks to improve their financial status and in embracing shared prosperity. It also calls for the integration of more open policy feedback mechanisms and social mobility through technological empowerment.Social implicationsSocially, this study underscores the importance of social cohesion and mobility, facilitated by technological empowerment, in the pursuit of shared prosperity and financial well-being. It also emphasizes the role of education in fostering political awareness necessary for sustaining these efforts.Originality/valueThis is a nascent study, with its focusing on individual grassroots perspectives and its identification of mediators like technological empowerment and responsible citizenship within the context of a developing, multi-ethnic nation. Methodologically, the study contributes a reliable and valid instrument for the further exploration of shared prosperity and financial well-being in literature.
Strategies for E-retailers to cope with supply chain disruption: a hybrid perspective on sourcing and pricing
Authors: Huang He , Xu Yuchen , Wang Youhao , Zhao Ziwei 
Published: January 2025

PurposeIn this digital age and risk society, this study aims to explore innovative strategies for E-retailers during supply chain disruptions to construct a more resilient supply chain system.Design/methodology/approachVarious game theoretical models are constructed to analyze four supply chain scenarios. Meanwhile, sufficient numerical analysis was conducted to observe the impact of key parameters on supply chain strategies.FindingsMultiple crucial factors exert a comprehensive influence on E-retailers’ decisions on sourcing and pricing, leading to the diversity and complexity of decision-making conditions. First, with the increased probability of disruption, the purchase quantities of the E-retailer from different suppliers are not in a linear changing pattern, and the total purchase quantity is allocated variably between different suppliers. Second, the variation in disruption severity (partial or complete) results in the shift of decisions between single-sourcing and dual-sourcing. Responsive pricing is conducive to increasing the purchase quantity and profits under partial disruption; its advantages are diminished when completely disrupted. Third, higher commission rates usually have a detrimental impact on profit, whereas responsive pricing may mitigate this impact.Originality/valueUnlike the previous single perspective, this study innovatively explores strategies from the hybrid perspective of sourcing and pricing. By extracting two key factors (disruption probability and severity), it realizes the scientific characterization of supply chain disruptions. These achievements boost theoretical innovation. Concentrating on E-retailers, it avoids the generalization of conclusions and enhances the application value.
Developing a resilient humanitarian value ecosystem: a systematic review on humanitarian financing using topic modelling
Authors: Guan Chong , Tay Huay Ling , Zhao Qitong 
Published: January 2025

PurposeThis study systematically reviews the research landscape of humanitarian financing, identifying key themes and pathways to foster a resilient humanitarian value ecosystem.Design/methodology/approachA systematic review using BERTopic analysed 1,043 academic publications from the Web of Science database to uncover major themes in humanitarian financing literature.FindingsSix core themes emerged from the study: Disaster Risk and Climate Change Resilience, Refugee Crises and Humanitarian Health Services, Preparedness and Response to Health Emergencies, Supply Chain and Logistics Fundraising, Food Security and Nutrition Insecurity and Global Health Challenges and Disease Control. The study highlights the role of financing in addressing short-term needs and promoting long-term systemic resilience, such as disaster preparedness, healthcare systems and food security.Research limitations/implicationsThis study provides a comprehensive overview of key research trends in humanitarian financing. However, the reliance on academic literature limits the inclusion of insights from grey literature and practitioner reports. Future studies should adopt broader data sources and interdisciplinary approaches.Practical implicationsFindings underscore the importance of integrating emergency funds with long-term resilience investments, enhancing financial transparency and advocating innovations to optimise humanitarian operations.Social implicationsThe study advocates for interdisciplinary approaches and policies connecting disaster risk reduction, healthcare, climate resilience and food security to build a sustainable humanitarian ecosystem.Originality/valueThis review proposes a novel conceptual framework based on a systematic review of literature using BERTopic, offering actionable insights into the role of humanitarian financing in addressing global crises and promoting resilience.