bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PROFITABILITAS, LEVERAGE, GOOD CORPORATE GOVERNANCE TERHADAP NILAI PERUSAHAAN
Authors: Isyfa Fuhrotun  
Published: December 2022

Tujuan penelitian ini adalah menganalisis pengaruh profitabilitas terhadap nilai perusahaan, pengaruh leverage terhadap nilai perusahaan, dan pengaruh Good Coorporate Governance terhadap nilai perusahaan.
Penelitian ini menggunakan jenis data sekunder bersifat kuantitatif dan sumber data diperoleh dari www.idx.co.id. Populasi yang digunakan adalah perusahaan LQ45 yang terdaftar di Bursa Efek Indonesia (BEI) tahun 2016-2019.Metode pengambilan sampel dari penelitian ini adalah dengan purposive sampling. Teknik analisis data yang digunakan yaitu analisis regresi linear berganda dengan jumlah sampel sebanyak 106.
Berdasarkan metode uji asumsi klasik yang menunjukkan bahwa semua variabel yang digunakan memenuhi asumsi serta tidak terdapat pelanggaran, demikian uji F dan uji R menunjukkan model yang diajukan layak digunakan. Hasil analisis data menunjukkan bahwa variabel profitabilitas berpengaruh positif dan signifikan terhadap nilai perusahaan. Leverage berpengaruh positif dan signifikan terhadap nilai perusahaan. GCG berpengaruh positif dan signifikan terhadap nilai.
Sosialisasi Ketentuan Perubahan Struktur Koperasi Di Era Pandemi Covid 19 Bersama Koperasi Hikmah Berkah Silaturahim
Authors: Wahyudi  
Published: December 2022

Pandemi covid 19 mempunyai dampak yang sangat besar terhadap sektor perekonomian, tidak terkecuali bidang usaha koperasi. Menghadapi hal tersebut koperasi berusaha bertahan dengan berbagai cara, salah satunya melakukan perubahan struktur koperasi. Tujuan pengabdian kepada masyarakat ini untuk menambah wawasan pengetahuan bagi anggota koperasi. Metode yang digunakan dalam kegiatan ini melalui sosialisasi penyuluhan hukum. Hasil yang diperoleh dalam kegiatan ini terlihat dalam simulasi rapat anggota tahunan koperasi dengan bahasan pokok perubahan struktur pengurus koperasi. Pengurus koperasi bertugas untuk mengelola kegiatan dan bidang usaha dengan tujuan untuk kesejahteraan anggota. Perubahan pengurus dilakukan melalui rapat anggota koperasi yang dilakukan secara tatap muka atau secara daring. Keputusan dari rapat anggota tahunan tersebut dilaporkan kepada pemerintah atau pemerintah daerah berdasarkan wilayah keanggotaan koperasi. Pengawasan kegiatan koperasi dilakukan oleh pemerintah sebagai bentuk perlindungan hukum terhadap anggota koperasi yang terdaftar, jika dalam pengawasan ditemukan pelanggaran maka pemerintah berwenang unutk memberikan sanksi administratif. Kegiatan pengabdian kepada masyarakat ini mempunyai dampak yang cukup signifikan dengan indikator pemahaman ketentuan peraturan perundang-undangan yang berlaku bagi anggota dan pengurus koperasi hikmah berkah silaturahim.
Sarojini Naidu: The Singer of Beautiful Songs
Authors: Shatakshi Misra  
Published: December 2022

Sarojini Naidu was an Indian political activist, feminist, and poet, a proponent of civil rights, women’s emancipation, and anti-imperialistic ideas. Despite all these qualities, she was known as “The Singer of Beautiful Songs” she will always be remembered and recalled by her two names: “The Nightingale of India” and” Bharat Kokila” as Mahatma Gandhi ornamented her. The present paper is a genuine effort to reveal her personality as a singer of beautiful songs; she emerged as the very soul of India and was attached firmly to its soil. Despite all her western garb and literary affiliation with the English poets, her sensibility was “wholly native.” Blessed with remarkable creative talent, she adroitly composed charming songs with a striking note of native fervour. In this task, she fell into the tradition of Indian women writers since the Vedic age. In the tradition of Vishwavara and Ghosha, the singers of sonorous songs in Vedas of Gargie, Maitreyi, and Sulabha, the unchangeable Upanishadic debaters of Sumana, Shyama, Sumangala, Sangh Mitra, and Rajyashri.
An in vitro study of zinc effect on Trichomonas vaginalis isolated from infected women
Authors: Ali Salih Ahlam , Obaid Hiro Mohammed , M. Jasim Wafa 
Published: December 2022

The most common non-viral sexual transmission disease in humans, trichomoniasis, is caused by the protozoan parasite Trichomonas vaginalis (STD). Metronidazole is the most frequently recommended of the imidazole drugs used to treat trichomoniasis. In any case, these substances may result in undesired side effects and parasite resistance. As a result, this infection needs to be treated in a different way.
Aim: This study was designed to determine the relation between zinc intake and the Trichomonas vaginalis occurrence and also to find out the in vitro effect of zinc on T. vaginalis viability.
Methods: This study was carried out on 63 pregnant women whom attended (Azadi Teaching, Kirkuk General and Al-Nasr maternity) Hospitals from December 2021 till April 2022. Specimens of vaginal swabs and serum samples were obtained from all pregnant women. The swabs were first examined directly by normal saline on slide microscopically then inoculated onto Modified Diamond medium. Zinc levels and concentrations in the blood were assessed using serum. Result: T. vaginails was isolated from pregnant women. The overall prevalence among 63 examined samples were positive by direct microscopically and culture with a rate of 5(8%) while 58 (92%) were negative. The 1.5mg/ml zinc concentration was the most effective on T. vaginalis trophozoites number than other concentration of zinc. Conclusion: Zinc is a very important anti- T. vaginalis and can be used it as dilution washing for treatment process.
INFLUENCE DES FIRMES DE PRODUITS DE SANTE, LIENS ET CONFLITS D'INTERETS. PERCEPTION DES ETUDIANTS DE TROISIEME CYCLE DE MEDECINE GENERALE
Authors: VASSELON Q , VALLEE J 
Published: December 2022

Introduction. La Conférence nationale des doyens a établi une charte éthique et déontologique qui préconise le renforcement des enseignements sur l’information médicale et le risque de perte d’indépendance. La faculté de Saint-Étienne propose des formations aux liens et conflits d’intérêts en troisième cycle de médecine générale. Objectifs. Explorer les perceptions des internes de médecine générale stéphanois de l’influence des firmes, des liens et conflits d’intérêts et leurs souhaits de participation à des formations sur ces thèmes. Mé thodes. Étude qualitative par théorisation ancrée. Entretiens semi-dirigés analysés par catégories, auprès de 18 internes de médecine générale réalisée de décembre 2020 à juin 2021. Résultats. Hormis deux internes formés initialement hors de France, les participant·e·s ont été en contact répété et habituel avec les firmes dès le second cycle, plus souvent en stage hospitalier. Les positions des médecins encadrants ont rarement été discutées au cours du cursus. Majoritairement conscients des techniques d’influence, plusieurs participant·e·s exprimaient un sentiment d’invulnérabilité. Pour leur formation continue professionnelle, certain·e·s gardaient des contacts avec les firmes, d’autres pas. Conclusion. Une formation sur les liens et conflits d’intérêts devrait être effectuée dès le premier cycle des études médicales et réitérée au cours du cursus. Les médecins hospitaliers ou de ville encadrants devraient instaurer un dialogue sur ces thèmes avec les étudiants. Ces propositions pourraient permettre aux étudiants d’exercer leur libre arbitre. Enseigner durant la formation initiale les modalités de formation médicale continue indépendante contribuera à aider leur choix.
Cache Coherence issues and Solution: A Review
Authors: Alkhamisi Khalid 
Published: December 2022

Computer systems are extensively being used in today’s era and the advancement in computer systems has led to the evolution of various technologies. As the efficiency of the computer systems is to be enhanced, the usage of cache memory becomes a must. The cache memory problems occur when multiprocessor systems are used. When multiple processors are processors share a common memory pool, the problem of cache coherence occurs. Cache coherence is a state in which the cache memories of the processors must stay in coherence with each other. The data should be updated in all the cache systems. Various protocols are used to ensure cache coherence. This study delineates the cache memory architecture, cache coherence, and the issues that arise due to non-consistent data in the cache of multiprocessor systems. Moreover, this study also delineates the protocols of the cache coherence and also describes in detail the MISE protocol. This study will provide an in-depth review of cache, cache coherence, and the issues associated with cache coherence along with the solution.
Application of analytic hierarchy process (AHP) to evaluate maintenance practices in TVET institutions in Kenya
Authors: Njeru George Njagi , Muchiri Peter Ng'ang'a 
Published: December 2022

TVET institutions are expected to produce the bulk of Kenya’s middle level manpower equipped with skills to drive the attainment of infrastructural objectives of Kenya Vision 2030. However inadequate training resources brought about by poor management practices continue to impede efforts to equip Kenyan youth with employable technical skills. A programme to re-equip the institutions has been effected but it requires maintenance practices to be aligned with the new acquisitions to ensure they are constantly available for training. A survey was conducted through a questionnaire to engineering departments to evaluate compliance with maintenance performance indicators (PIs); a 5-point rating scale was used to score responses in the questionnaire that returned a combined Maintenance Management System Effectiveness Index of 0.517. This indicated a need for improvement of maintenance practices. The Analytical Hierarchical Process (AHP) method was applied which identified predictive maintenance policy as the best one to apply
Efficacy of Aloe secundiflora crude plant extract against Candida albicans and Penicillium marneffei
Authors: Ndiba Patrick Mutharia , Waihenya Rebecca 
Published: December 2022

Abstract
Medicinal plants have been used in production of various drugs singly or in combination and even as principal raw material for the production of other conventional medicines. There are a number of Aloe species that grow wildly in Kenya. Ten mature leaves of Aloe secundiflora were collected and the crude plant extract was obtained and prepared according to Waihenya et al., 2003. It was then tested for antifungal activity against Candida albicans and Penicillium marneffei. In- vitro studies on the efficacy of crude extracts of A. secundiflora on C.albicans and P. marneffei were conducted. The results of the study revealed considerable zones of inhibition of Candida albicans growth caused by Aloe secundiflora crude plant extract on Sabouraoud agar. There was also growth inhibition of the Penicillium marneffei which is known to cause infections in immunosuppressed hosts and in non-AIDS patients with hematological malignancies and those receiving immunosuppressive therapy. Our results suggests that, the extract can be used to prevent the aflatoxins caused by Aspergillus species and the superficial mycosis that result from fungal infection and probably any other kind of mycoses. Further studies are required starting with experimental models to establish the in-vivo activity of the crude extract, the active ingredient, dosage and safety of A.secundiflora, before recommending it for clinical use.

Keywords: Aloe secundiflora, Immunosuppressed hosts, Crude extract, Candida albicans, Penicillium marneffei
RANCANG ULANG TATA LETAK RAK DAN PERALATAN KERJA DI UNIT RM SECARA ERGONOMIS DI RUMAH SAKIT TINGKAT III BRAWIJAYA SURABAYA
Authors: Ali Amir , Nurlaili Novita , Sudirman Sudirman , Setiawan Ade 
Published: December 2022

Latar Belakang : Ruang penyimpanan berkas rekam medis di Rumah Sakit Tingkat III Brawijaya Surabaya berada di lantai satu memiliki luas 15 m x 8 m dan didalamnya terdapat 16 buah rak penyimpanan serta merupakan tempat penyimpanan BRM. Ruang penyimpanan berkas rekam medis di sini juga masih belum memenuhi standar ilmu ergonomi, Seperti tidak memaksimalkan pencarian berkas dan penempatan berkas saat dibutuhkan, Pengaturan tata letak yang belum baik membuat perekam medis tidak nyaman saat bekerja.

Tujuan : Tujuan dari penelitian adalah melakukan perancangan ulang tata letak rak dan peralatan kerja di unit rm secara ergonomis di RS Tingkat III Brawijaya Surabaya.

Metode : Penelitian ini menggunakan penelitian deskriptif dengan pendekatan kuantitatif yaitu dengan tujuan untuk merancang ulang tata letak rak dan peralatan kerja di ruang penyimpanan berkas rekam medis sesuai dengan standar ergonomi. Sampel penelitian menggunakan teknik total sampling yaitu semua anggota populasi digunakan menjadi sampel. Sampel yang digunakan yaitu 4 orang petugas rekam medis. Pengumpulan data melalui observasi menggunakan alat meter ukur.

Hasil : Untuk ukuran tata ruang filing di Rumah Sakit Tingkat III Brawijaya Surabaya yang disesuaikan dengan data antropometri petugas filing ialah tinggi rak 180 cm disesuaikan menjadi 185,5 cm, panjang rak 229,5 cm disesuaikan menjadi 142,5 cm, lebar rak 50 cm disesuaikan menjadi 54 cm, jarak antar rak 63 cm disesuaikan menjadi 102 cm, luas ruangan 120 m2. Ukuran yang dihasilkan dari pengukuran di Rumah Sakit Tingkat III Brawijaya Surabaya lebih kecil dibandingkan ukuran yang diperoleh dari hasil perhitungan.

Kesimpulan : Perancangan ruang penyimpanan BRM aktif di Rumah Sakit Tingkat III Brawijaya Surabaya yang sudah memenuhi standar ergonomi, dimana ruang kerja petugas penyimpanan BRM terasa lebih nyaman. Selain itu BRM dapat tersusun dengan rapi dan dapat menampung lebih banyak BRM, jarak antara rak satu dengan lainnya yang sudah memenuhi standar disbanding sebelumnya.
Mature Wistar Rats' Spleen and Liver Histomorphological Changes Related to the Duration of Atrazine Exposure
Authors: Odi Praise Ajiri , Udi Onoriode Andrew , Chris-Ozoko Lilia Ebeye , Oyovwi Mega Obukohwo 
Published: December 2022

Background: Spleen and liver is secondary lymphoid organ that is highly sensitive to different chemicals. Widespread use of pesticides in agriculture has always been a matter of concern. And surprisingly, atrazine distinguishes out for being used more frequently among numerous harmful pesticides. As a result, long term exposure to atrazine and other pesticides is thought to produce metabolic abnormalities; however, little is known about how atrazine affects the spleen and liver and how this relates to its histo-achitectural structure.
Aim: The histopathology of the spleen and liver from rats exposed to atrazine was the subject of our investigation.
Materials and Methods: Twenty male wistar rats ranging from 150-200g were acclimated to laboratory conditions for 14 days, following which they were randomly assigned into 4 groups 1, 2, 3 and 4 of 5 animals each based on average body weight. Groups (2-4) were administered atrazine via oral route corresponding to 1237 mg/kg (20/5 LD50), 618 mg/kg (10/5 LD50) and 309 mg/Kg/body weight (1/10 LD50) for 7, 14 and 30 days, while group I (control) received distilled water orally using orogastric canula for 30 days . The liver and spleen from each group of rats were harvested, weighed, and fixed in 10% buffered formal saline fixative before being taken for histological examination 24 hours following the experimental periods of oral administration of the extract.
Results: At the end of the experiment, the histological findings showed increased and numerous area of the white pulp of spleen from rats exposed to atrazine as compared to that from the control. The relative area of germinal centre in the structure of the splenic lymph follicles of rats exposed to atrazine also revealed increased. Also, Histo-pathologically, the liver showed necrotic hepatic cells and congested central vein, with the highest atrazine concentration causing the most adverse effects.
Conclusion: Our data demonstrated that rats exposed to high-dose of atrazine led to hypertrophy of white pulp of the spleen and hepatic cell damage with liver. From this we concluded that both organ are highly sensitive to the debilitating effects of atrazine.
Correlation between Corneal Biomechanics and Lamina Cribrosa Curvature in Primary Open Angle Glaucoma
Authors: Shalaby Alaa Mohamed Abd Elhameed , Shalaby Said Mohamad , Shaheen Mohamed Abd El-Fatah , Nassar El Sayed Abbas 
Published: December 2022

Background: Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide. This condition is distinguished by progressive optic neuropathy, excavation of the optic disc, and characteristic visual field abnormalities. Intraocular pressure (IOP) elevation is the primary risk factor. Due to the same collagen makeup of the cornea and sclera, the cornea and lamina cribrosa (LC) may have similar biomechanical qualities. In the present study. This study aimed to establish the association between corneal biomechanical parameters and LC curvature in POAG-affected eyes.
Methods: This prospective comparative cross-sectional investigation was conducted on sixty eyes at the Tanta University ophthalmology department. There were 30 eyes with primary open-angle glaucoma and 30 eyes with normal age, gender, and refraction. The corneal biomechanical parameters applanation 1 length and velocity (A1L, A1V), applanation 2 length and velocity (A2L, A2V), peak distance (PD), the radius of curvature (R), and deformation amplitude (DA) were measured using a non-contact Scheimpflug-based tonometer (corvids ST). LC curvature was determined by measuring the LC curvature index (LCCI) using spectral-domain optical coherence tomography B-scan pictures (OCT). The data were gathered and analyzed using a suitable statistical tool.
Results: Mean A1V was significantly lower (P=0.027) in the POAG group (0.13 ± 0.02 m/sec) than the control groupn(0.14 ± 0.01 m/sec). PD was significantly increased (P=0.05) in the POAG group (4.30± 0.54 mm) than the control group (3.99± 0.66 mm). R was significantly higher (P=0.004) in the POAG group (7.90± 0.93 mm) than in the control group (7.14± 1.04 mm). DA was significantly lower (P<0.001) in the POAG group (0.95± 0.06 mm) than in the control group (1.11± 0.02 mm). LCCI was significantly higher (P<0.001) in the POAG group (10.69 ± 1.77) than in the control group (6.90 ± 0.93). LCCI showed a positive significant correlation with PD and R and a negative significant correlation with DA.
Conclusions: The corneas of POAG eyes were less deformed than those of normal controls. In POAG patients, corneas with less deformability were related to a more posteriorly bent LC. This result may explain why corneal biomechanics may be utilized to evaluate and predict glaucoma risk and progression. Corvis ST is a novel non-contact tonometer that allows for simple estimation of corneal biomechanics and should be used routinely in patient monitoring.
Composition Engineering of Perovskite Single Crystals for High‐Performance Optoelectronics
Authors: Zhang Yunxia , Liu Yucheng , Liu Shengzhong (Frank) 
Published: December 2022

AbstractComposition engineering, with its advantages to effectively tune semiconductor properties by regulating chemical stoichiometry, is a proven strategy to boost the efficiency and stability of ABX3 perovskite photoelectronic devices. Compared with its counterpart polycrystalline perovskite film, single crystalline is the ideal model for exploring its fundamental scientific issues. In this review, a critical overview of recent advances of the growth strategies, properties, and functional applications of multicomponent perovskite single crystals (SCs) is presented. First, the underlying advantages of composition engineering of perovskite SCs are discussed and then the different composition tuning strategies, including A‐site, B‐site, X‐site, and simultaneous A‐ and X‐site engineering, are systematically summarized. Subsequently, the benefits of composition engineering are highlighted for optimizing photovoltaic and photoelectronic devices. Lastly, controversies and remaining challenges for the development of composition engineering of perovskite SCs are discussed and a brief perspective regarding further investigation in this field is provided.
Highly Sensitive Self‐Powered 2D Perovskite Photodiodes with Dual Interface Passivations
Authors: Ji Ting , Zhang Haibo , Guo Jiahao , Wang Yingkui , Shi Linlin , Wu Yukun , Wang Wenyan , Li Guohui , Wen Rong , Xiao Liantuan , Su Qingmei , Xu Bingshe , Chen Hongzheng , Cui Yanxia 
Published: December 2022

Abstract2D perovskites have attracted intensive attention by virtue of their excellent optical and electrical properties along with good stabilities. Herein, a highly sensitive self‐powered photodiode based on (PEA)2(MA)4Pb5I16 (PEA=C6H5(CH2)NH3, MA=CH3NH3) 2D perovskite is demonstrated by dual interface passivations. The Al2O3 bottom passivation can reduce the pinhole defects in the 2D perovskite film and suppress the trap‐related recombination loss, bringing forward much reduced dark current and increased photocurrent. The poly (methyl methacrylate) (PMMA) top passivation can encapsulate the 2D perovskite film and thus improve the stability of the device. These results show that the 2D perovskite‐based photodiode with dual interface passivations exhibits a large photo‐to‐dark current ratio of 107, a fast response speed of 597 ns and a linear dynamic range of 160 dB without bias. Responsivity (R) and detectivity (D*) respectively reach 0.36 A W−1 and 5.4 × 1012 Jones under 532 nm laser illumination at a power density of 1.5 nW cm−2. Moreover, the dual interface passivated device exhibits good stabilities. This study paves the road for developing low‐cost, low‐power, solution processed image sensors.
Unveiling the Multiple Tumor‐Targeted Impairments of Covalent‐Organic Framework‐Switched Photothermal Shielding Nanoparticles
Authors: Qin Yanhui , Zhang Xiaoyi , Lächelt Ulrich , Huang Rongqin 
Published: December 2022

AbstractCovalent organic framework (COF) receives great attention in biomedical applications due to its variable compositions and ordered structures. However, its targeted design to achieve desirable physiological functions especially for cancer treatments remains elusive. Herein, PEGylated COF with tumor‐specific TKD peptide modification is uniformly coated on photothermal mesoporous carbon nanospheres via polyethyleneimine‐mediated interface polymerization to construct a multifunctional core‐shell nanoparticle (OPCPT). Physicochemical studies demonstrate near infrared (NIR)‐blocking ability of the crystalline COF shells under physiological conditions, whereas COF is degraded under the acidic tumor microenvironments (TME). Subsequently, the nanoparticle charge is reversed and the COF monomers can produce 1O2/O2. As a result, OPCPT, activated in the TME due to the shell dissociation, penetrates deeply into tumors through positive charge‐mediated/lysosome rupture‐mediated transcytosis and recovers its NIR‐heating potential for tumor‐specific photothermal therapy. Moreover, the TME‐triggered 1O2 significantly depresses the lysosome autophagy via membrane destruction, and selectively damages the mitochondria to promote the cytochrome C release‐activated apoptosis and ATP deficiency‐inhibited tumor metastasis. Particularly, this unique O2 generation mechanism relieves the tumor hypoxia upon the reactive oxygen species therapy and downregulates hypoxia‐inducible factor and its downstream proteins, which all contribute to augmented tumor therapy. The findings represent a remarkable unveiling of the potential of COF‐based nanomaterials for extended biomedical applications.