bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serotonin Degeneration and Amyloid-β Deposition in Mild Cognitive Impairment: Relationship to Cognitive Deficits
Authors: Smith Gwenn S. , Kuwabara Hiroto , Yan Haijuan , Nassery Najlla , Yoon Mark , Kamath Vidya , Kraut Michael , Gould Neda F. , Savonenko Alena , Coughlin Jennifer M. , Lodge Martin , Pomper Martin G. , Nandi Ayon , Holt Daniel , Dannals Robert F. , Leoutsakos Jeannie M. 
Published: September 2023

Background: Neuropathological and neuroimaging studies have demonstrated degeneration of the serotonin system in Alzheimer’s disease (AD). Neuroimaging studies have extended these observations to the preclinical stages of AD, mild cognitive impairment (MCI). Serotonin degeneration has been observed also in transgenic amyloid mouse models, prior to widespread cortical distribution of amyloid-β (Aβ). Objective: The present study evaluated the regional distribution of the serotonin transporter (5-HTT) and of Aβ in individuals with MCI and healthy older controls, as well as the contribution of 5-HTT and Aβ to cognitive deficits. Methods: Forty-nine MCI participants and 45 healthy older controls underwent positron emission tomography (PET) imaging of 5-HTT and Aβ, structural magnetic resonance imaging and neuropsychological assessments. Results: Lower cortical, striatal, and limbic 5-HTT and higher cortical Aβ was observed in MCIs relative to healthy controls. Lower 5-HTT, mainly in limbic regions, was correlated with greater deficits in auditory-verbal and visual-spatial memory and semantic, not phonemic fluency. Higher cortical A β was associated with greater deficits in auditory-verbal and visual-spatial memory and in semantic, not phonemic fluency. When modeling the association between cognition, gray matter volumes and Aβ, inclusion of 5-HTT in limbic and in select cortical regions significantly improved model fit for auditory-verbal and visual-spatial memory and semantic, but not phonemic fluency. Conclusions: These results support the role of serotonin degeneration in the memory and semantic fluency deficits observed in MCI.
Screening of Actinomycetes Isolated from Soil and their Antimicrobial Activity against Plant Pathogens
Authors: Zamir Rahat , Mazhar Sumaira , Shafique Huma , Yasmin Roheela 
Published: September 2023

Actinomycetes abundantly present in soil are renowned for various secondary metabolites production with a wide range of use in diverse fields of life. Many reports are available on the use of actinomycetes for the regulation of pathogenic microbes in plants. For this purpose, this study used thirteen Actinomycetes strains, which were isolated from the fields of Piplan (district Mianwali) Punjab, Pakistan. However, out of thirteen, only seven were found active for the production of both primary and secondary screening. The active seven actinomycetes (AW1, AW2, AW3, AW4, AM1, AC1, and AC2) were separated for their microbial potential against pathogenic strains (Escherichia coli and Staphylococcus aureus) isolated from the same agriculture soil. About 42.85% of isolated actinomycetes (three out of seven) showed antagonistic properties against S. aureu and E. coli in primary screening. Thus, it was noticed that the three strains (AW3, AM1, and AC1) had great antimicrobial potential, which showed the most promising results. Whereas in Secondary screening only AC1 showed the best result with ethyl acetate extract as compared to ethanol, methanol, and chloroform. Hence, It was concluded that actinomycetes isolates had great potential for antibacterial activity and they can be used in agriculture industry for the regulation of plant pathogens.
La salud intercultural como complemento de la medicina occidental en México
Authors: Rodríguez Pacheco Juana , Osuna Flores Israel 
Published: September 2023

El objetivo del presente trabajo es analizar los factores que han provocado la falta de complementariedad entre la medicina tradicional y la occidental, para coadyuvar a enriquecer y alentar la interacción y comprensión entre estas dos importantes áreas del conocimiento médico. Se llevó a cabo una revisión bibliográfica y documental sobre aspectos de salud intercultural en general y en particular en México. La salud intercultural es el resultado de la complementariedad del sistema de salud occidental y tradicional milenario de los pueblos y comunidades indígenas y afro mexicanas. Se requiere de una mayor interacción entre la medicina occidental e indígena y unos de los factores que frenan la complementariedad son la comunicación, reconocimiento de la diversidad lingüística y la falta de capacitación de los profesionales de salud que inciden en la atención a la salud en estas comunidades marginadas. Se tiene que seguir alentando la interacción entre estas dos importantes áreas del conocimiento médico en México.
Phenomenon of Female Composer in Musical Culture of China in the Twentieth Century
Authors: Qiu Difan 
Published: September 2023

The purpose of the article is to identify the specifics of the role of women composers in the musical culture of China in the twentieth century. The research methodology consists in applying the methods of analysis and synthesis, systematisation of facts, comparison and generalisation of the research results. The systemic-historical method allowed the author to consider the formation of female archetypes in the Chinese musical culture of the twentieth century. With the help of the comparative method, the stages of the creative development of women composers in the Chinese national culture of the twentieth century were structured. The scientific novelty of the study lies in an attempt to reveal the originality of the Chinese musical avant-garde, to identify the role of women composers in the musical culture of China in the twentieth century and the level of influence of Chinese traditional and Western compositional techniques of various stylistic techniques on their work. Conclusions. The synthesis of Chinese philosophy, archaic folk music and Western compositional techniques reveals the originality of the Chinese musical avant-garde of the twentieth century. For centuries, women's rights were severely restricted. However, at the beginning of the twentieth century, important reform processes were launched that led to a change in the social status of women in China, including the musical sphere. Starting in the mid-twenieth century, women composers, on the one hand, cultivated the musical traditions of their country, and, on the other hand, were influenced by Western compositional technologies. In this context, a special place is occupied by the Chinese composer Du Yun and her monumental opera "Angel's Bone" — a delicate psychological canvas that successfully combines the styles of different eras.
Key words: musical culture of China, phenomenon of female composers, tradition, originality of Chinese culture, influence of Western musical culture.
Stage Unity of D. Lider’s Plastic Concept of Scenography and S. Danchenko’s Theatre Direction
Authors: Gusakova Nina , Devizorov Maksym 
Published: September 2023

The purpose of the study is to highlight the stage unity of the plastic concept of D. Lider’s scenography and S. Danchenko’s theatre direction, to characterise the original concept of the image of the performances, their uniqueness of artistic solution. The research methodology is to apply the functional and typological method to consider the scenographic activity of D. Lider as an innovative form of artistic creativity in the context of the formation and development of the direction of effective scenography, as well as to assess its significance in the development of scenographic vocabulary of the Ivan Franko National Academic Drama Theatre. The art method is used to analyse the scenographic solution of the performances directed by S. Danchenko and to identify the main conditions and principles of scenographic solutions, compositional techniques and components of D. Lider’s scenography, as well as to determine their influence on the artistic image of the productions. An axiomatic method helped consider Danylo ider's worldview prerogatives in the context of the peculiarities of the formation of his philosophy and artistic and aesthetic position as a master of effective scenography. The novelty of the study. The article comprehensively examines the stage unity of the plastic concept of D. Lider’s scenography and S. Danchenko’s theatre direction in the context of the formation and development of the scenography of the Ivan Franko National Academic Drama Theatre. Conclusions. As a philosopher of theatre, D. Lider’s scenography is not guided by any prescribed rules, and it is impossible to judge it by means of a defining judgment, by imposing certain already known categories on his scenographic vocabulary. The scenery created by the master testifies to an innovative form of the sublime that allows for the acquisition of creative energy – D. Leader sought to overcome the dictates of sensual perception of reality in order to reflect the essential, hidden characteristics of existence. The associative connection and drawing parallels between the actual problems of the present and the problems of a literary work as the basis for deep philosophical and aesthetic reflections introduced by D. Lider is the basis of Ukrainian stage art of the twenty-first century.
Key words: Danylo Lider, Serhii Danchenko, director, theatre, scenography.
МОДИФІКОВАНИЙ МЕТОД СХОДЖЕННЯ ПО ОПУКЛІЙ ПОВЕРХНІ ПРИ ВІДСТЕЖЕННІ ТОЧКИ МАКСИМАЛЬНОЇ ПОТУЖНОСТІ СИСТЕМИ ЕЛЕКТРОПОСТАЧАННЯ СУПУТНИКА
Authors: Jasim Ali Mahmood 
Published: September 2023

The increasing of efficiency of the satellite electrical power supply system (PSS) is important engineering task. Modern satellite PSS widely use DC-DC converters under pulse-width controlling. Existing methods of maximum power point tracking of such systems not always can to search surely for maximum power point if there are existing some local maximums of power. It can be if illumination of few non-oriented solar panels are different. This paper present the modeling of modified hill climbing (HC) maximum power point tracking (MPPT). The aspect of the method is choosing initial point through open circuit voltage coefficient and next tracking by using of special function through digital differentiation of measured values of output power with scaling on actual power and special empirical coefficient. The simulation results revealed robust tracking of the main peak power at a sufficiently rapid convergence.
ВИКОРИСТАННЯ ТЕПЛОТИ ГАРЯЧОЇ ВОДИ СУДНОВОГО МАЛООБЕРТОВОГО ДИЗЕЛЯ КОГЕНЕРАЦІЙНОГО ТИПУ ДЛЯ ОХОЛОДЖЕННЯ ЦИКЛОВОГО ПОВІТРЯ ЕЖЕКТОРНИМ ТЕРМОТРАНСФОРМАТОРОМ
Authors: Радченко Николай Иванович , Стахель Андрей , Богданов Николай Семенович , Щербак Юрий Георгиевич 
Published: September 2023

The evaluation of the fuel efficiency and a depth of marine low speed diesel engine cyclic air cooling by transforming into a cold of the heat of hot water produced by the heat of exhaust gas and scavenge air and spended for heating demands during cool periods of the ship performance has been done. The influence of a depth of the scavenge air heat utilization upon the effect due to its cooling was investigated. It was shown that because of low efficiency of heat transformation by refrigerant ejector chiller caused by insufficient high heat potential of heating water (temperature of about 90 °С) the fuel saving is much more less than potentially possible its value.
ВИЗНАЧЕННЯ ПАРАМЕТРІВ ГОФРУ ПІД ЧАC КОМБІНОВАНОЇ ОПЕРАЦІЇ РЕДУКУВАННЯ ТА ГОФРОУТВОРЕННЯ ТРУБНИХ ЗАГОТІВОК
Authors: Борисевич Володимир Володимирович , Абухабел Мохамед Абубакер 
Published: September 2023

The results of numerical modelling of corrugation forming at combination of reduction and corrugation formation of the tubular blanks are given. There were sequentially modelled initial buckling with symmetrical bulging and further plastic flow. The results of modelling were compared for the different parameters of the technological process and for the different correlation of the initial blank dimensions. It is shown, that applied model describes corrugation formation adequately. Application of the model proposed is recommended for calculation of the parameters of the corrugation formation process with axial displacement of the material to the zone of deformation.
МЕТОД ОПЕРАТИВНОГО КОНТРОЛЯ ДАННЫХ В СИСТЕМЕ ОСТАТОЧНЫХ КЛАССОВ, ОСНОВАННЫЙ НА ПРИНЦИПЕ ПОСЛЕДОВАТЕЛЬНОЙ НУЛЕВИЗАЦИИ
Authors: Краснобаев Виктор Анатольевич , Кошман Сергей Александрович , Янко Алина Сергеевна 
Published: September 2023

The method for real-time data control within the system of residue classes (SRC), based on the consecutive nullification principle is considered. This method is implemented by applying a sequential procedure of nullification with next remainder of position-independent code structure. Main procedure of the method is the following: while it is selected nullification’s constant for the number for the residue’s value for the base , in the calculating path of a computer system in SRC, which is functioning on the base , it can be formed the residue’s value by which the next stage of nullification will be doing the next constant nullification’s constant . The results of assessment and comparative analysis of testing time in SRC are presented
ІНТЕРВАЛЬНИЙ МЕТОД ОЦІНЮВАННЯ ДОВІРИ ТА РЕПУТАЦІЇ В СОЦІАЛЬНІЙ МЕРЕЖІ
Authors: Вартанян Василій Михайлович , Туркіна Вікторія Валентинівна 
Published: September 2023

The problem of trust and reputation systems in social networks estimation's are considered. The interval representation models of the trust are used for the uncertainty accounting. The method of determining trust/reputation in social networks is implemented as a sequence of actions: definition of the trust to provider is based on their reputation, subscriber’s choice for interaction is made by criterion of maximum expected value of their utility function, then correction of the numerical estimation of trust and reputation of the selected subscriber is performed.
МЕТОД СИНТЕЗУ РІШЕНЬ ЗАДАЧІ ПРОГНОЗУВАННЯ СТАНУ ПАЦІЄНТІВ В СИСТЕМАХ МЕДИЧНОГО МОНІТОРИНГУ
Authors: Горячая Вероника Александровна , Угрюмов Михаил Леонидович , Гайденко Олег Александрович , Бакуменко Нина Станиславовна , Трофимова Ирина Алексеевна 
Published: September 2023

This article proposes a mathematical model and computational method for solutions synthesis to the condition prediction problem of patients in medical monitoring systems. Research describes construction method of diagnostic models for quality criteria assessment of a bio-medical system (BMS) elements condition using monitoring data. Authors show an informativeness (significance) estimation method of the systems diagnosing models variables, obtained based on artificial neural networks (ANN) theory. The article describes a forecasting method of multidimensional time series obtained based on the condition variables monitoring data of the dynamic systems. Authors present a method for solving the condition classification problem of the complex systems elements. The developed method for solutions synthesis to the prediction problem is implemented in the computer decision support system (CDSS) for diagnosing patients in medical monitoring systems. Application examples of the described method for solutions synthesis to the condition prediction problem of patients in medical institutions are presented.The paper propose following developed innovations:a) Mathematical method for solutions synthesis to the condition prediction problem of patients based on trend-analysis concept. Unlike existing, this method takes into account the high dimensionality of the states space and informativeness changes of monitored variables, which depend on the patients’ condition.b) Method of informativeness (significance) variables estimation. It takes into account the measurement accuracy of the state variables and the presence of pair correlation between them, that allows to use this method for the analysis of the completeness of the models.c) Statistical method of the patients’ condition classification. It contains orthogonalization procedure and the dimension reduction procedure of the condition variables factor space. In contrast to the existing it uses as a closeness measure precedents in the principal components space and the ability to determine the disease stage, which is not recognized by modern bio-markers (for example, hormone-refractory state);The classification problem of the patients condition was solved for the diagnosing result verification. The results of solving the classification problem of patients condition based on the monitoring data are obtained for the selected type of disease. It was found that with the using developed method and its implementation in CDSS the itself- recognizing probability of the class exceeds 75%.
ІНФОРМАЦІЙНА ПІДТРИМКА ПРОЦЕСІВ МОНІТОРИНГУ ТА КОНТРОЛЮ У ПРОЕКТАХ
Authors: Мартиненко Олександр Сергійович , Гусєва Юлія Юріївна , Чумаченко Ігор Володимирович 
Published: September 2023

The need to make grounded decisions while monitoring and managing the requirements of stakeholders is an integral part of the project management as a whole, which, in particular, determines the quality and success of the project. Known models and methods of project monitoring and control do not have a separate tool for monitoring the fulfillment of the requirements of stakeholders in projects and programs. Earlier authors suggested a model of juxtaposition of the hierarchical structure of the project with the hierarchical structure of the project requirements, the hierarchical structure of the project risks, the hierarchical structure of the project resources, and the organizational structure of the project. Thus, the "work-requirement”, "work-resource", "work-responsible", "work-risk" model (4R & WS) was established. The proposed method allows tracking the dynamics of project implementation by factors of the model (risks, requirements, resources, stakeholders, executors). The practical use of the method requires the formalization of the above relationships. If the relationship between "work-responsible" and "work-resource" can be specified explicitly, the links between "work-and-risk" and "work-requirement" should be given in the fuzzy form.The purpose of this article is to provide informational support for the 4R & WS method by constructing a process for formalizing fuzzy connections of the corresponding model.The process of formalization of fuzzy relationships was carried out to provide information support for the project monitoring and control method based on the comparison of the hierarchical structure of project activities with the hierarchical structure of project requirements, the hierarchical structure of project risks, the hierarchical structure of project resources, and the organizational structure of the project. A functional model of the process is constructed. The use of the results of expert evaluation for the construction of membership functions is suggested. The methods of constructing membership functions are analyzed; the use of the method of statistical processing of expert information is justified.
МАТЕМАТИЧНІ МОДЕЛІ І ІНФОРМАЦІЙНІ ТЕХНОЛОГІЇ КОМПОНУВАЛЬНОГО СИНТЕЗУ СФЕРИЧНИХ КОНФІГУРАЦІЙ
Authors: Карташов Алексей Викторович , Коробчинский Кирилл Петрович 
Published: September 2023

The concept of layout synthesis of optimal configurations is introduced in the article. Under the tasks of layout synthesis it means the formation of a set of geometric objects in such a mutual arrangement that would satisfy the given relations (constraints, properties) and would deliver an extremum to a certain quality criterion. One problem of finding the optimal configuration of geometric objects of spherical shape is considered. The problem is to find such an arrangement of set of spheres without their mutual overlaps, so that their spherical shell is minimal. For this problem, several equivalent mathematical models are given. Since the problem is NP-complete, methods are considered for solving it, based on the search and improvement of local minima.To find one local minimum, it can be used any method of non-linear optimization. In this paper it is used an open system IPOPT for solving optimization problems, using the methods of internal points to search for a local minimum.To search for a local minima, there are used several approaches. The first of them is based on the application of the space expansion method. This method consists in finding a local minimum for a problem with constant radii, and then at the resulting point, a transition to a model with variable radii is made, in which the initial values of the radii of the circles change in a certain range in a random way. After that, the local search is performed again, and so many times. This approach allows for a directed search of a local minima, improving the solution.The second approach is based on a multiple search for a local minima using a genetic algorithm.The third approach is an interactive and uses human intuition. After obtaining some solution, the result is displayed in a graphical editor and the researcher can change the mutual position of objects, after which one of the automatic methods is applied. It is necessary that initial position objects do not be feasible. When solving a problem, it is necessary to ensure interaction between different stages of the solution. To do this, it is need to repeatedly convert geometric information from one form to another. Information technologies for the transformation of geometric information in the process of solving the problem are proposed.An example of a numerical solution is given.
CERMINAN KUASA MELALUI PERIBAHASA MELAYU YANG BEROBJEKKAN ‘GAJAH’ DAN ‘HARIMAU’
Authors: Nopiah Julaina , Addli Mohammad Aasim , Osman Maizura 
Published: September 2023

Peribahasa berobjekkan haiwan digunakan sebagai simbol bagi menggambarkan realiti kehidupan masyarakat Melayu dan mempunyai nilainya yang tersendiri untuk dijadikan panduan hidup. Cara hidup orang Melayu lama yang selalu meneliti unsur alam dan mengenali sifat haiwan menyebabkan mereka menggunakan haiwan sebagai simbol untuk berkias dan memberikan teguran. Makalah ini bertujuan untuk mengenal pasti peribahasa yang menonjolkan konsep kuasa melalui objek ‘gajah’ dan ‘harimau’ Merungkai perkaitan antara objek dan aspek pemaknaan peribahasa yang berobjekkan ‘gajah’ dan ‘harimau’ melalui pendekatan semantik inkuisitif. Data peribahasa Melayu telah dikumpulkan daripada pangkalan data www.malaycivilization.com dan Kamus Istimewa Peribahasa Melayu. Daripada sejumlah 275 peribahasa yang berobjekkan haiwan, lapan peribahasa yang berobjekkan ‘gajah’ dan ‘harimau’ telah dikenal pasti mengandungi kuasa sebagai aspek pemaknaannya. Kajian ini mengaplikasikan pendekatan Rangka Rujuk Silang (RRS) dan pendekatan semantik inkuisitif dalam penganalisisan data. Data yang diperoleh telah diperkukuh dengan hasil janaan data korpus yang menunjukkan persamaan antara ciri-ciri fizikal yang dipunyai oleh haiwan tersebut dengan konsep kekuasaan yang terdapat dalam elemen pemaknaannya. Kekuatan gajah yang terletak kepada ‘saiznya’, manakala kekuatan harimau pula terletak kepada ‘ ‘belangnya’. Kekuatan bagi kedua-dua haiwan ini, telah menyebabkan masyarakat Melayu menganalogikannya sebagai cerminan kekuasaan dalam peribahasa. Gabungan data, teori, falsafah dan budaya yang terdapat dalam semantik inkuisitif menjadi medan dalam dapat menghasilkan huraian makna yang merungkai perkaitan antara objek peribahasa yang digunakan dengan elemen pemaknaannya.