bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASPEK HUKUM PERJANJIAN LISENSI TERHADAP MEREK BERDASARKAN UNDANG-UNDANG NOMOR 20 TAHUN 2016
Authors: Nur Hidayat Sri Sulastri & 
Published: January 2023

Lisensi adalah izin yang diberikan oleh pemilik Kekayaan Intelektual kepada pihak lain berdasarkan perjanjian secara tertulis sesuai peraturan perrrndang-undangan untukmenggunakan Kekayaan Intelektual.sebagaimana dimaksud dalam Undang-Undang Nomor 30 Tahun 2000 tentang Rahasia Dagang, Undang-Undang Nomor 31 Tahun 2000 tentang Desain Industri, Undang-Undang Nomor 32 Tahun 2000 tentang Desain Tata Letak Sirkuit Terpadu, Undang-Undang Nomor 28 Tahun 2014 tentang Hak Cipta, Undang-Undang Nomor 13 Tahun 2016 tentang Paten, dan Undang-Undang Nomor 20 Tahun 2016 tentang Merek dan Indikasi Geografis.Perjanjian Lisensi harus dilakukan secara tertulis serta harus dicatatkan agar supaya Perjanjian tersebut mempunyai akibat hukum pada pihak ketiga.Perjanjian Lisensi terhadap Merek berdasarkan Undang-undang Nomor 20 tahun 2016 tentang Merek dan Indikasi Geografis harus berupa Merek terdaftar serta merek tersebut tidak berakhir masa perlindungannya dan juga tidak dalam telah dihapuskan.Perjanjian Lisensi Merek yang telah dilakukan antar pihak , masih dapat dilakukan perjanjian lisensi merek dengan pihak ketiga sepanjang tidak diperjanjikan lain.Dalam perjanjian Lisensi merek baik Penerima Lisensi maupun Pemberi Lisensi masing masing dapat menggunakan Merek tersebut sesuai dengan perjanjian yang telah disepakatinya dan juga sepanjang tidak diperjanjikan lain pemberi Lisensi dapat memberikan Lisensi atas Merek terdaftar miliknya kepada pihak ketiga.Tenggang waktu lamanya Pencatatan Lisensi Merek mengikuti tenggang waktu lamanya perjanjian Lisensi merek serta isi dari perjanjian lisensi merek dapat dirubah sewaktu-waktu sesuai kesepakan pemberi dan penerima Lisensi , begitu juga dapat dicabut apabila ada kesepakatan antara pemeberi dan penerima lisensi , karena adanya putusan pengadilan atau sebab lain yang dibenarkan berdasarkan ketentuan peraturan perundang-undangan.
TRADISI BHEN-GIBHEN PADA PERKAWINAN ADAT MADURA DALAM PERSPEKTIF NILAI LOKAL MADURA
Authors: Maulana Arief 
Published: January 2023

AbstrakMadura mempunyai sejarah yang panjang. Di masa kerajaan singasari, pulau ini menjadi salah satu kabupaten dengan adipatinya yang sangat terkenal, Arya Wiraraja. Jika kita lihat dari sekilas sejarahnya, Jawa mempunyai pengaruh atas Madura. Masyarakat Madura juga mempunyai tradisi perkawinan. Seperti disinggung di atas, bahwa dalam masyarakat Madura mempunyai tradisi yang unik. Di dalam perkawinan Madura, seorang anak biasanya sudah dijodohkan sejak kecil. Dibalik sejarah diatas, jika kita berpikir tentang masyarakat Madura, maka prasangka kita terhadap penilaian Madura lebih condong negative dengan berbagai stereotipe. Tradisi adat perkawinan Madura merupakan hal yang menarik dari berbagai segi kehidupan. Tidak hanya itu, perkawinan adat di Madura juga masih kental dengan kearifan lokal (local wisdom) yang masih dipegang teguh dan dilaksanakan secara turun-temurun. Seperti tradisi "Bhen-Gibhen" yang sampai hari ini masih tetap dilakukan oleh masyarakat Madura.Kata Kunci: Bhen-Ghiben, Adat Perkawinan, Orang Madura
MENGANALISIS ROKAT BUMI MENURUT PRESPEKTIF ISLAM
Authors: Fatahillah Izet Alfian 
Published: January 2023

AbstrakArtikel ini bertujuan untuk memberikan gambaran dan pengetahuan tentang kearifan lokal adat Madura “Rokat Tana” yang terletak di Desa Bapelle, Sampang, Madura. Penelitian ini menggunakan metode penelitian kualitatif terhadap lapangan,penelitian ini untuk memberikan pandangan dan pengetahuan tentang “rokat tana” di desa tersebut. Penelitian ini menggunakan Teknik wawancara dan observasi lapangan dengan beberapa masyarakat di desa tersebut agar data yang diperoleh sesuai dengan yang ada di lapangan dan sesuai fakta.Kata kunci: Adat, rokat tana, Bapelle.
Pengembangan Bahan Ajar Mata Palajaran Pendidikan Agama Islam Berbentuk Modul Dengan Model Borg Dan Gall Terhadap Siswa Kelas Xi Semester Ganjil Di SMA Negeri 2 Situbondo Tahun Pelajaran 2015/2016
Authors: Hakim Lukman Nul 
Published: January 2023

Abstrak
Penelitian pengembangan ini dilakukan untuk mengembangkan bahan ajar mata pelajaran PAI berupa model borg and gall. Dalam bentuk modul baik untuk siswa atau pegangan guru sekaligus untuk mengetahui sejauh mana efektifitas dari modul tersebut. Pengembangan bahan ajar ini menggunakan langkah-langkah pengembangan model pengembangan dengan desain R & D dari Borg dan Gall memiliki tujuan untuk mengembangkan sekaligus memvalidasi produk. Adapun beberapa tahapan pengembangan model tersebut adalah sebagai berikut : (1) penelitian dan pengumpulan informasi, (2) perencanaan, (3) pengembangan produk, (4) uji lapangan awal, (5) revisi produk utama, (6) uji lapangan lanjut, (7) revisi produk operasional, (8) uji lapangan operasional, (9) uji lapangan akhir dan (10) diseminasi dan implementasi. Namun dalam penelitian tesis dan desertasi Borg and Gall menyarankan untuk membatasi penelitian dalam skala kecil. Data yang akan diuraikan berikut ini meliputi, (1) data uji coba ahli materi, (2) data uji coba ahli media, (3) data uji coba ahli bahasa, (4) data uji coba perorangan, (5) data uji coba kelompok kecil, (6) data uji coba lapangan yang diperoleh dari satu guru mata pelajaran pendidikan agama islam dan 34 siswa (7) hasil belajar siswa dengan menggunakan produk pengembangan bahan ajar mata pelajaran Pendidikan Agama Islam yang berupa modul dengan model borg and gall, untuk mengetahui tingkat keefektifan terhadap bahan ajar berupa modul yang diterapkan menunjukkan perbedaan yang signifikan antara skor sebelum dan sesudah menggunakan bahan ajar berupa modul yang baru.
Kata kunci
Bahan Ajar, PAI, Modul Model Borg and Gall.
Konsep Negara Islam
Authors: Amina Siti 
Published: January 2023

Al-Mawardi adalah ulama yang produktif, hal ini terbukti dari banyaknya karya-karya beliau dalam banyak berbagai bidang kedisiplinan ilmu. Al-Ahkam as-Sultaniyyah wa al-wilayah al-Diniyyah adalah karya terakhir beliau yang nama al-Mawardi dikenal hingga kini. Tulisan ini merupakan karya ilmiah pertama yang membahas ilmu politik dan administrasi negara dalam sejarah Islam dan masih merupakan buku rujukan utama bagi para ulama dan pemikir politik Islam di bidang politik dan pemerintahan. Teori politik yang dikemukakan al-Mawardi adalah penting karena merupakan upaya pertama dalam sejarah Islam yang membahas dan menyusun teori kenegaraan secara lengkap, di samping karena berpengaruh besar terhadap pemikiran politik Islam sampai dewasa ini.
Dalam pandangan Al-Mawardi, sebuah Negara harus memiliki 6 sendi yaitu pertama, menjadikan agama sebagai pedoman, kedua, memiliki pemimpin yang bijak dan otoritas yang ada pada diri pemimpin tersebut, ketiga, memiliki keadilan yang merata dan menyeluruh yang dimana semua itu akan menciptakan suatau perdamaian, keempat, keamanan semesta yang akan memberikan keamanan, kelima, kesuburan tanah air dan terakhir, harapan bertahan dan mengembangkan kehidupan.
Perencanaan Arsitektur Enterprise Pada Labor Komputer STMIK Dumai Dengan Enterprise Architecture Planning
Authors: Yunita Putri , Salsabila Annisa , Anggirani Kiki , Sari Sri Indah 
Published: January 2023

STMIK Dumai adalah sebuah institusi pendidikan tinggi yang telah menggunakan SI/TI dalam menjalankan proses bisnisnya. Fasilitas kelas menjadi salah satu pendukung dalam proses belajar mengajar termasuk segala fasilitas perkuliahan yang disediakan di STMIK Dumai. Telah dilakukan Penelitian pada labor komputer STMIK Dumai dalam melakukan pelaporan kerusakan komputer dengan menggunakan metode Enterprise Architecture Planning (EAP). Penelitian dilatarbelakangi oleh pelaporan yang masih dilakukan secara manual pada labor komputer. Penelitian ini dilakukan dengan mewawancarai asisten labor secara langsung. Sehingga dibuatlah sebuah sistem yang digunakan untuk melakukan pelaporan secara komputerisasi agar mempermudah dan mempercepat pelaporan dengan menggunakan metode Enterprise Architecture Planning (EAP). Hasil dari proses pelaporan kerusakan komputer, disajikan dalam bentuk laporan kerusakan. Laporan ini dapat digunakan untuk melihat kondisi fasilitas labor komputer bagi pimpinan dan unsur lainnya dalam peningkatan kualitas fasilitas di labor komputer STMIK Dumai.
Corticosteroids Resistance Diseases Review
Authors: Alghamdi Doha , Alghamdi Abdulrahman 
Published: January 2023

Glucocorticoids, the main anti-inflammatory medication, are useful for the treatment of many diseases such as inflammation, respiratory diseases, malignancies, etc., but unfortunately, glucocorticoids cannot inhibit inflammation by various mechanisms. The definition of glucocorticoid resistance is loss of efficacy or reduced sensitization over time and increases due to chronic inflammation. It is affecting 30% of glucocorticoid-treated patients. It shows an essential restriction in the treatment of chronic inflammation and malignancies diseases and can be due to the impairment of various mechanisms along the signaling pathway of glucocorticoids. However, glucocorticoids dissociation has been improved to reduce the SE, DIGRAs “receptor of glucocorticoid dissociation agonists” are a group of trial drugs developed to share various wanted as an anti-inflammatory, suppress immunity, or properties of anti-malignancies of traditional steroids medications with lesser adverse events, but it is so hard to dissociate anti-inflammatory effects from adverse effects. Cases with glucocorticoid unresponsive should use other medications with similar mechanisms in inflammation as well as drugs that may change the molecular mechanism of resistance to glucocorticoid. Here, we discuss the evidence that exists for the hypothesis that individual glucocorticoid resistance underlies the problem.
Ensaio teórico sobre o uso das redes neurais artificiais no gerenciamento de resultados
Authors: Da Silveira Elmo Dias , De Souza Paulo Vitor Souza , De Britto Paulo Augusto Pettenuzzo 
Published: January 2023

A Rede Neural Artificial (RNA) tem capacidade de simular uma rede neural biológica e apresenta-se como uma ferramenta que pode auxiliar na redução de problemas econométricos mediante modelos matemáticos. Modelos de gerenciamento de resultados apresentam um problema fundamental pelo fato dos accruals discricionários da gestão não serem diretamente observáveis, o que vem a afetar a avaliação do desempenho real de empresas. Portanto, este ensaio tem como objetivo apresentar a RNA como uma abordagem que pode minimizar problemas observados em modelos de gerenciamento de resultados por accruals. A literatura sobre gerenciamento de resultados apresenta diversos problemas relacionados aos modelos por accruals: proxies não confiáveis, interpretação restrita, incentivos, existência de condições simultâneas, problemas de correlação, classificação e especificação em modelos de gerenciamento, entre outros. Com base no suporte teórico apresentado pela literatura, entende-se que a utilização da abordagem da RNA pode proporcionar melhores níveis de poder e especificidade em modelos de gerenciamento de resultados por accruals. Este estudo visa contribuir com diversos usuários da informação contábil por evidenciar problemas em modelos de gerenciamento, bem como apresentar uma proposta baseada em inteligência artificial como solução para os problemas observados.
An In-vitro Study of the Effect of Hydroethanol Extract of Annona senegalensis Leaves on Bitis rhinoceros (Viperidae) Venom Induced Coagulopathy
Authors: Julien Golly Koffi , Marcel Ahon Gnamien , Antoinette Yapo-Crezoit Chiayé Claire , Hermann Akaffou Marc , Benoit Yobouet Dedrekwaku Camman , Bernard Allali Kouadio , Karamoko Ouattara , Mireille Dosso , Joseph Djaman Allico 
Published: January 2023

Bites of Bitis Rhinoceros (Viperidae) usually cause a hemorrhagic syndrome in the victims. This is a medical emergency. Antivenom immunotherapy remains effective. However, its availability and cost still limiting its use in Africa in general and in Côte d'Ivoire particularly. The roots of a plant of the Annonaceae family (Annona senegalensis) are used in Côte d'Ivoire to treat cases of envenomations by Viperidae. The objective of this work is to study the modulation of the effect of Bitis rhinoceros venom on coagulation parameters by the hydroethanol extract of Annona senegalensis leaves.
The phytochemical study of the plant was carried out by monitoring effect of the venom on three blood coagulation parameters (PT, APTT, Fibrinogen) from healthy individuals in the presence and absence of the hydro-ethanolic extract. Phytochemistry revealed the presence of saponins, tannins, and polyphenolic compounds including flavonoids in this plant.
The study of the effect of the venom showed that at the concentration of 10-2 mg/mL the venom of Bitis rhinoceros modifies some coagulation parameters by the decrease of half of the prothrombin rate, the increase of the coagulation time. It has no effect on the fibrinogen level.
The effect of this venom is inhibited by 1 mg/mL of the hydroethanol extract. The leaves of Annona senegalensis contain molecules that could neutralize the action of the venom in the coagulation disorder.
Accumulation of Heavy Metals by Some Aquatic Macrophytes in Two Streams along the Tiko-Douala Highway, Cameroon
Authors: Fonge B. A. , Awo M. E. , Tabot P. T. , Akango C. , Kenko D. , Djeugo C. 
Published: January 2023

Aims: This study was aimed at determining the ecological health of two roadside streams across the Tiko-Douala highway, Cameroon, and investigating the phytoremediation potentials of dominant aquatic macrophytes within these streams.
Study Design: Water, sediments, and aquatic plant samples were collected from Camp 7 and Moqouo streams, and analyzed for ammonium nitrogen, nitrate nitrogen, phosphates, magnesium, cadmium, and lead, including other relevant water quality parameters.
Place and Duration of Study: In the Life Science Laboratory of the University of Buea, and Soil and Water Laboratory of the University of Dschang, Cameroon between June 2021 and June 2022.
Methodology: Six water samples and six sediment samples were collected per stream, and two of the most dominant plant species (Pennisetum purpureum Schumach (Poaceae) and Dicanthelium clandestinum L. (Poaceae) from Camp 7, Commelina benghalensis L. (Commelinaceae) and Oldenlandia corymbosa L.(Rubiaceae) from Moqouo stream) were collected for heavy metal analysis. Heavy metal concentration and bioaccumulation factors were determined for each plant.

Results: High concentrations of phosphates were recorded in Camp 7 (1.19 mg/L) and Moqouo (2.17 mg/L) streams. Dissolved oxygen levels were 0.69 mg/L and 0.80 mg/L in Camp 7 and Moqouo respectively. Sediment cadmium levels ranged from 0.33± 0.02 to 0.63± 0.16 mg/kg, and lead ranged from 0.34 ±0.03 to 0.37 ± 0.12 mg/kg in Moqouo and Camp 7 respectively.
Conclusion: The Mouqouo and Camp 7 streams are rich in phosphates and thus not suitable for drinking and irrigation. Cadmium and lead in stream water were within the permissible limits but sediments contained higher concentrations than water and therefore they could be released gradually into the water column. All plants in the study except (Dicanthelium cladestinum) accumulated cadmium and lead, and could be potential plants for the phytoremediation of these metals.
Impasses and Nuances of Vaccination for COVID-19 in Children Aged 5-11 Years
Authors: Nicoly F. Figueiredo, , Yitzhak V. Núñez, , Karla P. M. Pérez, , Caroline P. Moreira, , J Gonçalves Júnior, , Estelita L. Cândido, 
Published: January 2023

Background: In relation to COVID-19, pediatric patients are usually asymptomatic or with mild manifestations of lesser severity. On the other hand, the literature demonstrates the reduced existence of cases that progressed to serious complications. Therefore, the release of a vaccine for this age group is extremely important for children's health and for reducing the spread of the virus. Furthermore, the immunization of children against SARS-CoV-2 was implemented in some countries and, as a result, the panorama regarding this subject has changed completely, being saturated with opinions and divergences related to the topic. In view of this, the present article aims to clarify the nuances of SARS-Cov-2 immunization in children between the ages of 5-11 years old.
Methodology: For this study, we have conducted a review on the literature regarding vaccination against COVID-19 on the 5-11 years pediatric age group, using the MeSh terms "COVID-19", "vaccination", "children", and "pandemic", in the following databases: "Google Scholar", "PubMed" and "BVS".
Results: Overall, the research has shown that the most common side effects in the pediatric age group, when present, were local pain (48,7%), headache (20,4%), fatigue (27,7%), myalgia (11,4%), and local erythema (11,4%), whilst severe symptoms, such as myocarditis, occurred with a low incidence (0,16%).
Conclusion: Due to the absence or, if present, mild /local side effects on children, the recommendations of the main health agencies are in favor of the immunization of this age group, although, further work on the social opinion is needed in order to increase public acceptance concerning the importance and safety of vaccination against COVID-19 in children between the ages of 5-11.
Algorithm-Based Palliative Care in Patients With Cancer
Authors: Parikh Ravi B. , Ferrell William J. , Li Yang , Chen Jinbo , Bilbrey Larry , Johnson Nicole , White Jenna , Sedhom Ramy , Dickson Natalie R. , Schleicher Stephen , Bekelman Justin E. , Mudumbi Sandhya 
Published: February 2025

ImportanceAmong patients with advanced solid malignant tumors, early specialty palliative care (PC) is guideline recommended, but strategies to increase PC access and effectiveness in community oncology are lacking.ObjectiveTo test whether algorithm-based defaults with opting out and accountable justification embedded in the electronic health record (EHR) increase completed PC visits.Design, Setting, and ParticipantsThis 2-arm cluster randomized clinical trial was conducted from November 1, 2022, to December 31, 2023. Eligible patients from 15 urban or rural clinics within a large community oncology network in Tennessee had advanced lung or noncolorectal gastrointestinal cancer and were identified by an automated EHR algorithm adapted from national guidelines. Data were analyzed between November 1, 2023, and March 4, 2024.InterventionAt sites randomized to control, clinicians received weekly reports detailing PC referral rates compared with peer clinicians (peer comparison) and referred patients to PC at their discretion. At sites randomized to intervention, clinicians also received default PC orders using the EHR. Clinicians who opted out of PC consultation were asked to provide justification (accountable justification). If clinicians did not opt out, a study coordinator contacted patients to introduce and schedule PC visits using a standardized, predefined script.Main Outcomes and MeasuresThe primary outcome was a completed PC consultation within 12 weeks of enrollment. Exploratory outcomes included quality of life, feeling heard and understood, and intensive end-of-life care. Outcomes were analyzed using clustered generalized linear and logistic regression models.ResultsThe trial enrolled 562 patients (mean [SD] age, 68.5 [10.1] years; 288 male [51.2%]), of whom 433 (77.0%) had lung cancer. There were 130 of 296 patients (43.9%) randomized to the intervention group and 22 of 266 (8.3%) randomized to the control group who completed PC visits (adjusted odds ratio, 8.9 [95% CI, 5.5-14.6]; P &amp;lt; .001). Among 179 patients who died at the 24-week follow-up, 6 of 92 (6.5%) in the intervention group compared with 14 of 87 (16.1%) in the control group received systemic therapy within 14 days of death (adjusted odds ratio, 0.3 [95% CI, 0.1-0.7]; P = .05). There were no differences in quality of life, feeling heard and understood, or late hospice referral.Conclusions and RelevanceIn this randomized clinical trial of algorithm-based EHR defaults, the intervention increased PC consultations and decreased end-of-life systemic therapy. The intervention provides a scalable implementation strategy to increase specialty PC referrals in the community oncology setting.Trial RegistrationClinicalTrials.gov Identifier: NCT05590962
Lifetime Socioeconomic Status, Cognitive Decline, and Brain Characteristics
Authors: Krueger Kristin R. , Desai Pankaja , Beck Todd , Barnes Lisa L. , Bond Jerenda , DeCarli Charles , Aggarwal Neelum T. , Evans Denis A. , Rajan Kumar B. 
Published: February 2025

IMPORTANCESocioeconomic status (SES) has an important association with cognitive function and structural brain indices. Identifying the nature of this association will guide strategies for improving health equity.OBJECTIVETo test the longitudinal associations of SES with cognitive decline and brain characteristics and to examine whether these associations differ between Black and White individuals.DESIGN, SETTING, AND PARTICIPANTSParticipants aged 65 years old or older were recruited for this population-based cohort study from 4 communities on the south side of Chicago, Illinois. At-home interviews were conducted between 1993 and 2012. The data were analyzed in April 2024.MAIN OUTCOMES AND MEASURESOutcome measures were level and change in global cognition and 4 individual tests. Three magnetic resonance imaging (MRI) measures of the brain included total brain volume, hippocampal volumes, and white matter hyperintensities (WMH). Childhood SES was assessed using parental education levels, father’s occupation, and childhood finance rating. Adulthood SES was assessed using the participants’ education, occupation, and income. Lifetime SES was assessed on the basis of the mother’s education, childhood SES, and participants’ occupation and income.RESULTSOf the 7303 participants (mean [SD] age, 72.3 [6.3] years; 4573 female participants [63%]), 4581 (63%) were non-Hispanic Black, and 2722 (37%) were non-Hispanic White. SES was higher for White individuals compared with Black individuals in childhood, adulthood, and across the lifespan. Higher lifetime SES was associated with better global cognitive functioning at baseline (estimate, 0.337; 95% CI, 0.317 to 0.357; P &amp;lt; .001) but not with decline over time (estimate, 0.003; 95% CI, −0.001 to 0.006; P = .10). Higher lifetime SES was associated with a better baseline score on the Mini-Mental State Examination (estimate, 0.281; 95% CI, 0.261 to 0.302; P &amp;lt; .001) and a slower decline for all participants (estimate, 0.012; 95% CI, 0.008 to 0.016; P &amp;lt; .001). In a subset of 933 participants who underwent MRI, there was an association between lifetime SES and healthier brain structures, as measured by total brain volume (estimate, 3.18; 95% CI, 0.20 to 6.17; P = .04) and WMH burden (estimate, −0.11; 95% CI, −0.21 to −0.01; P = .03).CONCLUSIONS AND RELEVANCEIn this cohort study, SES, mainly in adulthood, was associated with a person’s cognitive status and brain structure, resulting in a discrepancy in cognitive status over time. These findings point to a need for interventions that improve SES throughout the lifespan, particularly for Black individuals, who had lower SES than White individuals.