bluuebunny/crossref_metadata_2025_split huggingface dataset:
From Duck Lane to Lazarus Seaman
Authors: Woudhuysen H. R. 
Published: September 2023

Abstract
This chapter constitutes the first published outline of the trade in second-hand books and manuscripts in England during the sixteenth and seventeenth centuries. It gives an overview of the subject and is organized around three key events: the Dissolution of the Monasteries, the work of the Parliamentary Sequestration Committee, and the first known auction sale in the country—that of Lazarus Seaman in 1676. It goes slightly beyond that event and looks at the spread of auctions in the country before 1700. Particular attention is paid to the language used to describe the trade and to the locations in which it took place. Some consideration is given to booksellers’ warranties and to the significance of codes used to price second-hand books. In the course of the chapter, evidence from the collections of some notable figures—Ben Jonson, John Donne, James Ussher, Samuel Pepys among them—is cited.
Provenance Narratives in the Twenty-First Century
Authors: James Kathryn 
Published: September 2023

Abstract
This chapter examines the provenance narrative as a form of ontological mediation, a mechanism by which the text-object is framed as the focus of study. It argues that, as a narrative, the provenance history indelibly influences the categories by which the object is or isn’t presented to its observers. Taking the work of John Leland, Thomas Hearne, M. R. James, and others as its focus, the chapter argues that the Dissolution of the Monasteries and the consequent destruction of their libraries acted as an originating provenance for the study of the book in the early modern period. It examines the long consequences of this for the field of English Studies and the categories by which that field was defined and understood by practitioners from the sixteenth century onwards. One consequence can be seen in the prioritization of ideals of intactness, completeness, or textual recovery in English bibliographical work, and in the ways in which the text-object is defined through its relationship with the imagined plenum and prelapsarian state of a pre-dissolution world.
Conversations about Time and Space
Authors: Iyengar Sujata 
Published: September 2023

Abstract
This chapter defines and describes ‘bookness’, the phenomenology of codices and material texts as they encounter human bodies in time and space, through a sustained comparison between contemporary artists’ books and early modern books about counting, calculating, and identifying objects in the real world (field guides, including abecedaries), and imagining the universe (astronomical books). It foregrounds the functions of bookness in space, both private and public, historically and in the present by contrasting early modern, flexible uses of the codex form with contemporary artists’ books—limited edition, artisanal, or fine art print objects that, in Johanna Drucker’s phrase, consider the codex as ‘a form to interrogate’ rather than as ‘a vehicle for reproduction’. It concludes by suggesting that the deliberately archaic form of the printed book and the arguably elitist and certainly rarefied commodity of the artists’ or fine-press book highlights the beauty, fragility, and human-inflicted damage of the natural world.
Paediatric obesity and Crohn’s disease: a descriptive review of disease phenotype and clinical course
Authors: McCoy Jacob , Miller Michael R , Watson Melanie , Crowley Eileen , Woolfson Jessica P 
Published: September 2023

Abstract

Objectives
In an era of increasing paediatric obesity and inflammatory bowel disease (IBD), this study evaluates the disease phenotype and clinical course of Crohn’s disease (CD) in paediatric patients who are obese or overweight.

Methods
This is a retrospective, single-center, descriptive observational study from January 2010 to May 2020. Participants were included if they were: aged 2 to 18 years at the time of diagnosis, had a confirmed diagnosis of CD, and met WHO criteria for overweight or obesity at the time of diagnosis or within one year before diagnosis.

Results
A total of 345 patient charts with CD were screened during the study period, with 16 patients meeting inclusion criteria. Median age of patients was 15.5 years (IQR = 13.6, 16.1). Of the 15 patients over 10 years of age, median anthropometrics at diagnosis included body mass index (BMI) of 27.2 (IQR = 24.9, 29.4) and BMI for age z-score of 1.82 (IQR = 1.58, 2.19). Presenting symptoms included abdominal pain (80.0%), diarrhea (66.7%), hematochezia (66.7%), and weight loss (26.7%). Five patients (33.3%) had obesity-related complications. Median time from symptom onset to diagnosis was 146 days (IQR = 31, 367), and median time from diagnosis to remission was 229 days (IQR = 101.8, 496.3).

Conclusions
Patients with elevated BMI and CD present with typical symptoms of IBD, although weight loss was a less common presenting symptom. Time to disease remission is delayed, and obesity-related complications are common. Primary care providers must have a high degree of clinical suspicion in patients to prevent delays to gastroenterology referral and to improve time to disease remission.
Investigating the gut microbiota's influence on psoriasis and psoriatic arthritis risk: a Mendelian randomization analysis
Authors: Yu Nianzhou , Wang Jiayi , Liu Yuancheng , Guo Yeye 
Published: September 2023

Abstract

Background
Numerous investigations have revealed the interplay between gut microbiota (GM) and psoriasis (Ps) and psoriatic arthritis (PsA). However, the causal relationship between them remains unknown.

Methods
We curated a collection of genetic variants (P &lt; 1 × 10−5) associated with GM (n = 18 340) derived from the MiBioGen study. To explore the intricate relationship between GM and Ps as well as PsA, we harnessed the comprehensive resources of the FinnGen database, encompassing a vast cohort of individuals, including 4510 Ps cases and 212 242 controls and 1637 PsA cases and 212 242 controls. Mendelian randomization (MR) was used, including an inverse variance weighting method, followed by a sensitivity analysis to verify the robustness of the results.

Results
For Ps, some bacterial taxa, including Lactococcus, Ruminiclostridium 5, and Eubacterium fissicatena, were identified as risk factors; but Odoribacter demonstrated a protective effect against Ps. In the case of PsA, Lactococcus, Verrucomicrobiales, Akkermansia, Coprococcus 1, and Verrucomicrobiaceae were identified as risk factors; Odoribacter and Rikenellaceae exhibited a protective effect against the development of PsA.

Conclusion
Our study establishes a causal link between the GM and Ps and PsA. These findings provide insights into the underlying mechanisms and suggest potential therapeutic targets.
Global trade network patterns are coupled to fisheries sustainability
Authors: Elsler Laura G , Oostdijk Maartje , Gephart Jessica A , Free Christopher M , Zhao Junfu , Tekwa Eden , Bochniewicz Elaine M , Giron-Nava Alfredo , Johnson Andrew F 
Published: September 2023

Abstract
The rapid development of seafood trade networks alongside the decline in biomass of many marine populations raises important questions about the role of global trade in fisheries sustainability. Mounting empirical and theoretical evidence shows the importance of trade development on commercially exploited species. However, there is limited understanding of how the development of trade networks, such as differences in connectivity and duration, affects fisheries sustainability. In a global analysis of over 400,000 bilateral trade flows and stock status estimates for 876 exploited fish and marine invertebrates from 223 territories, we reveal patterns between seafood trade network indicators and fisheries sustainability using a dynamic panel regression analysis. We found that fragmented networks with strong connectivity within a group of countries and weaker links between those groups (modularity) are associated with higher relative biomass. From 1995 to 2015, modularity fluctuated, and the number of trade connections (degree) increased. Unlike previous studies, we found no relationship between the number or duration of trade connections and fisheries sustainability. Our results highlight the need to jointly investigate fisheries and trade. Improved coordination and partnerships between fisheries authorities and trade organizations present opportunities to foster more sustainable fisheries.
Vascular endothelial cell-specific disruption of theprofilin1gene leads to severe multiorgan pathology and inflammation causing mortality
Authors: Allen-Gondringer Abigail , Gau David , Varghese Christopher , Boone David , Stolz Donna , Larregina Adriana , Roy Partha 
Published: September 2023

AbstractActin-binding protein Profilin1 is an important regulator of actin cytoskeletal dynamics in cells and critical for embryonic development in higher eukaryotes. The objective of the present study was to examine the consequence of loss-of-function of Pfn1 in vascular endothelial cells (ECs) in vivo. We utilized a mouse model engineered for tamoxifen-inducible biallelic inactivation of the Pfn1 gene selectively in EC (Pfn1EC-KO). Widespread deletion of EC Pfn1 in adult mice leads to severe health complications presenting overt pathologies (endothelial cell death, infarct, and fibrosis) in major organ systems and evidence for inflammatory infiltrates, ultimately compromising the survival of animals within 3 weeks of gene ablation. Mice deficient in endothelial Pfn1 exhibit selective bias toward the proinflammatory myeloid-derived population of immune cells, a finding further supported by systemic elevation of proinflammatory cytokines. We further show that triggering Pfn1 depletion not only directly upregulates proinflammatory cytokine/chemokine gene expression in EC but also potentiates the paracrine effect of EC on proinflammatory gene expression in macrophages. Consistent with these findings, we provide further evidence for increased activation of Interferon Regulatory Factor 7 (IRF7) and STAT1 in EC when depleted of Pfn1. Collectively, these findings for the first time demonstrate a prominent immunological consequence of loss of endothelial Pfn1 and an indispensable role of endothelial Pfn1 in mammalian survival unlike tolerable phenotypes of Pfn1 loss in other differentiated cell types.
All the President’s Lies: Repeated False Claims and Public Opinion
Authors: Pillai Raunak M , Kim Eunji , Fazio Lisa K 
Published: September 2023

Abstract
A hallmark of the Trump presidency was a stream of false statements, many of which were repeated dozens or even hundreds of times. But whether (and to what extent) this repetition translates into public misperceptions remains an open question. We address this question by leveraging the most comprehensive data on Trump’s repetition of misleading claims during his presidency. In a national survey asking Americans to evaluate the truth of claims from this database, we find a clear partisan asymmetry. An increase in the number of repetitions of a falsehood corresponded with increased belief among Republicans but decreased belief among Democrats. We also find an important moderating role of media consumption. The effects of repetition were larger when people consumed more right-leaning cable news and when falsehoods were mostly repeated on Twitter. We discuss implications of these findings for misinformation research.
Grantmaking, Grading on a Curve, and the Paradox of Relative Evaluation in Nonmarkets
Authors: Adda Jérôme , Ottaviani Marco 
Published: September 2023

AbstractThe article develops a model of nonmarket allocation of resources such as the awarding of grants to meritorious projects, honors to outstanding students, or journal slots to quality publications. On the supply side, the available budget of grants is awarded to applicants who are evaluated most favorably according to the noisy information available to reviewers. On the demand side, stronger candidates are more likely to obtain grants and thus self-select into applying, given that applications are costly. We establish that if evaluation is perfect, grading on a curve inefficiently discourages even the very best candidates from applying. More generally, when the budget is insufficient to award grants to all applicants, the equilibrium unravels if information is symmetric enough—the paradox of relative evaluation. Leveraging a technique based on the quantile function pioneered by Lehmann, we characterize a broad set of nonmarket allocation rules under which an increase in evaluation noise in a field (or course) raises equilibrium applications in that field, and reduces applications in all other fields. We empirically confirm these comparative statics by exploiting a change in the rule for apportioning the total budget to applications in different fields at the European Research Council, showing that a 1 standard deviation increase in own evaluation noise leads to a 0.4 standard deviation increase in the number of applications and budget share. Moreover, we derive insights for the design of evaluation institutions, particularly regarding the endogenous choice of noise by fields or courses and the optimal aggregation of fields into panels.
Ocular Surface Regeneration by Limbal Stem Cells Therapies: State of the Art, Challenges, and Perspectives
Authors: Bonnet Clémence , González Sheyla , Deng Sophie X 
Published: September 2023

Abstract
Limbal stem cells (LSCs) are adult stem cells located at the limbus ensuring the continuous renewal of the corneal epithelium, critical to maintain an optimal visual function. Damages to the LSCs or their niche microenvironment lead to limbal stem cell deficiency (LSCD), a potentially blinding disease. Transplantation of LSCs as a treatment for severe to total LSCD has gained popularity since 1980s, owing to the clinical success of the first direct limbal autograft transplantation. Recent advances in the understanding of the LSCs’ molecular identity and regulation have enabled preclinical and clinical advancements of promising LSCs therapies. However, lack of standardization of the diagnostic methods, staging of the disease severity, manufacturing process, and clinical outcome measures have hindered the advancement of the therapy. To move these therapies to the clinic, optimization and standardization of the diagnostic strategy, cell product manufacturing, and assessment of clinical efficacy with potency assays are key points to the development of customized therapies. Recent findings suggest that residual LSCs exist in eyes presenting with clinical signs of total LSCD, which opens new therapeutic strategies for eyes with partial LSCD. Prospective, randomized, multicentric controlled clinical trials are necessary to determine the efficacy of different LSCs therapies for different stages of LSCD using a set of standardized outcome measures.
A culturally and linguistically adapted text-message Diabetes Prevention Program for Latinos: Feasibility, acceptability, and preliminary effectiveness
Authors: Formagini Taynara , Teruel Camargo Juliana , Perales-Puchalt Jaime , Drees Betty M , Fracachan Cabrera Monica , Ramírez Mariana 
Published: September 2023

Abstract
Despite the general positive outcomes of the Diabetes Prevention Program (DPP), the program’s reach, adherence, and effectiveness among Latinos are still suboptimal. Text-message DPP can potentially overcome barriers and improve DPP outcomes for this group. We aimed to assess the feasibility, acceptability, and preliminarily effectiveness of a culturally and linguistically adapted text-message DPP for Latinos. We enrolled 26 eligible Spanish-speaking Latino adults at risk of developing type 2 diabetes (A1c = 5.7%–6.4%, body mass index ≥25) in a 6-month culturally and linguistically adapted text-message DPP. Participants received (i) two to three daily automated text-messages about healthy eating, physical activity, problem-solving skills, lifestyle change motivation, and logistics, (ii) on-demand keyword-driven messages, and (iii) on-demand chat messages with a DPP coach. Outcomes included feasibility (e.g. adherence), acceptability (e.g. satisfaction), and preliminary effectiveness (e.g. weight loss). Twenty-four participants completed the program and follow-up assessments. Participants’ mean body weight changed from 191.2 to 186.7 pounds (P = .004); 45.8% of participants lost ≥3%, and 29.2% lost ≥5% of body weight. Body mass index and waist circumference were also reduced [0.9 kg/m2 (P = .003) and 1.1 cm (P = .03), pre–post]. Self-reported physical activity frequency was increased (P = .003). No statistically significant changes in diet quality were found. Most participants were satisfied with the program and perceived it to help prevent diabetes. Our pilot study of an innovative text-message DPP for Latinos demonstrated the program was acceptable, feasible, and potentially effective. Using text-message for DPP can reduce barriers to in-person participation by increasing the program’s reach without compromising fidelity and effectiveness.
Global trends and prospects in health economics of robotic surgery: A bibliometric analysis
Authors: Peng Yihao , Liu Yuancheng , Lai Sicen , Li Yixin , Lin Zexu , Hao Lingjia , Dong Jingyi , Li Xu , Huang Kai 
Published: September 2023

Background:
Over ten million robotic surgeries have been performed. However, the cost and benefit of robotic surgery need to be evaluated to help hospitals, surgeons, patients, and payers make proper choices, making a health economic analysis necessary. We revealed the bibliometric profile in the field of health economics of robotic surgery to prompt research development and guide future studies.

Materials and Methods:
The Web of Science Core Collection scientific database was searched for documents indexed from 2003 to December 31, 2022. Document types, years, authors, countries, institutions, journal sources, references, and keywords were analyzed and visualized using the Bibliometrix package, WPS Office software, Microsoft PowerPoint 2019, VOSviewer software (version 1.6.18), ggplot2, and Scimago Graphica.

Results:
The development of the health economics of robotic surgery can be divided into three phases: slow growing (2003-2009), developing (2010-2018), and fast-developing (2019-2022). HU JC and CHANG SL were the most active and influential authors, respectively. The USA produced the most documents, followed by China, and Italy. Korea had the highest number of citations per document. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES accepted most documents, whereas ANNALS OF SURGERY, EUROPEAN UROLOGY, and JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY had the highest number of citations per document. The JOURNAL OF ROBOTIC SURGERY is promising. The most cited document in this field is New Technology and Health Care Costs - The Case of Robot-Assisted Surgery in 2010. The proportion of documents on urology is decreasing, while documents in the field of arthrology are emerging and flourishing.

Conclusion:
Research on the health economics of robotic surgery has been unbalanced. Areas awaiting exploration have been identified. Collaboration between scholars and coverage with provisions for evidence development by the government is needed to learn more comprehensively about the health economics of robotic surgery.
The preliminary development and clinical verification of the positive index score scale of “Heart Arthralgia Syndrome”
Authors: Xu Sai , Chen Shouqiang , Xu Yunsheng 
Published: September 2023

Background:
In recent years, the age of onset for coronary heart disease (CHD) has become one of the leading causes of death worldwide. The medical treatments occasionally cause side effects; therefore, there is still an urgent need to develop new therapeutic modalities for CHD in clinical practice. "Heart Arthralgia Syndrome (HAS)" is a general term for CHD with arthralgia symptoms proposed by our team based on clinical experience. At present, there is little in-depth research on the treatment of HAS by TCM. Pick Complex Therapy (PCT) is an innovative and developed theory of collateral acupuncture therapy for HAS.

Methods:
We collected data from 276 patients who met the criteria for (coronary heart disease with numbness of neck, shoulder, waist, and leg). We selected 24 diagnostic criteria for HAS by means of multiple methods, including Cronbach’s α coefficient, retest reliability, subjective evaluation, discrete trend, Pearson’s rank correlation coefficient and factor analysis method. We thereafter evaluated the reliability, validity and responsiveness of the scale. In the clinical validation phase, we verified whether the preliminary developed positive index (PI) scale can guide clinical practice. Forty (40) patients with HAS were selected in the study. SPSS23.0 statistical software was used for statistical processing and analysis.

Results:
Assessment results of the initial PI scale for HAS: the average time to complete the scale was 7.47 ± 3.59 minutes. Cronbach’s α coefficient for the initial table was 0.711, the retest reliability was 0.897, the Kaiser-Meyer-Olkin test result was 0.844, and the Bartlett test result was 2502.300. Following maximum variance rotation analysis, the cumulative variance contribution rate was determined to be 66.605%. In the clinical validation phase of the PI scale, we tested 40 patients before and after the PCT treatments. After 3 measurements, the correlation between the PI scale for HAS and the angina pectoris grading scoring method table decreased gradually. The last 2 measurement results of study indicated that there was a significant correlation between the PI scale and thrombin time, while physical and chemical examination showed no significant changes.

Conclusion:
The PI scale for HAS can be widely used in the clinic as a preliminary evaluation tool for guiding PCT.
Bilateral femoral neck stress fractures in elderly individuals: A case report and literature review
Authors: Fang Zhanglu , Cao Jianhua , Wang Xun , Zhang Li 
Published: September 2023

Rationale:
Bilateral femoral neck stress fractures are relatively rare injuries that occur frequently in military recruits, athletes and patients with osteoporosis, renal bone disease, metabolic bone disease, and chronic steroid use. Herein, a case of an elderly patient with bilateral femoral neck stress fractures is reported.

Patient concerns:
A 65-year-old man presented to the author’s hospital with right hip pain for over a month. The patient was a farmer, had a long history of field labor before the onset of pain, denied any history of trauma.

Diagnosis:
The patient was diagnosed with a right subcapital fracture of the femoral neck after examination. The patient complained of only right hip symptoms, and hip computed tomography showed no abnormalities in the left hip. A tension fracture of the left femoral neck was missed due to unawareness of the abnormal signal of the left femoral neck seen on right hip magnetic resonance imaging.

Interventions:
During the first hospitalization, the patient underwent total hip arthroplasty (THA) on the right hip. Two months after the operation, the patient started to have pain in the left hip and underwent left THA again for a displaced left femoral neck fracture.

Outcomes:
The patient eventually underwent bilateral THA surgery and had a satisfactory functional recovery. But the oversight in the diagnostic process led to the patient undergoing left THA that could have been avoided.

Lessons:
For patients who complain of hip pain but deny a history of trauma, we should be concerned about the presence of a hip fracture even if the patient’s radiograph does not report a positive result. The most sensitive method is bilateral magnetic resonance imaging examination of the hip. Femoral neck stress fractures require early diagnosis and treatment to prevent complications.