bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case of epiglottic entrapment in a cat
Authors: Arbona Diana Victoria , Pratt Chap , Tearney Caitlin , Istvan Stephanie 
Published: July 2023

AbstractObjectiveThe objective of this study was to describe a case of epiglottic entrapment in a cat.Case SummaryA 5‐month‐old male neutered Russian Blue cat was evaluated for progressive stertorous upper airway sounds, acute onset vestibulopathy and abnormal laryngeal anatomy. Endotracheal intubation was only able to be achieved using videoscopic guidance and identified concern for severe nasopharyngeal stenosis. A computerized tomography scan revealed otitis interna, narrowed nasopharynx and no definitive cause for the stertorous breathing. The cat recovered very slowly from anaesthesia due to concern for airway obstruction following extubation. It was discharged the following day and then passed away at home 2 weeks later. Necropsy revealed that the epiglottis was obscured by 2 cm of redundant mucosal tissue extending from the base of the tongue to the larynx resulting in epiglottic entrapment. Also noted was chronic, severe otitis interna and externa. Upper airway obstruction is suspected to be the cause of sudden death.New or Unique InformationTo the authors’ knowledge, this is the first report of these oropharyngeal anatomic abnormalities in a cat.
Artificial Intelligence Techniques for Automatic Detection of Peri-implant Marginal Bone Remodeling in Intraoral Radiographs
Authors: Vera María , Gómez-Silva María José , Vera Vicente , López-González Clara I. , Aliaga Ignacio , Gascó Esther , Vera-González Vicente , Pedrera-Canal María , Besada-Portas Eva , Pajares Gonzalo 
Published: July 2023

AbstractPeri-implantitis can cause marginal bone remodeling around implants. The aim is to develop an automatic image processing approach based on two artificial intelligence (AI) techniques in intraoral (periapical and bitewing) radiographs to assist dentists in determining bone loss. The first is a deep learning (DL) object-detector (YOLOv3) to roughly identify (no exact localization is required) two objects: prosthesis (crown) and implant (screw). The second is an image understanding-based (IU) process to fine-tune lines on screw edges and to identify significant points (intensity bone changes, intersections between screw and crown). Distances between these points are used to compute bone loss. A total of 2920 radiographs were used for training (50%) and testing (50%) the DL process. The mAP@0.5 metric is used for performance evaluation of DL considering periapical/bitewing and screws/crowns in upper and lower jaws, with scores ranging from 0.537 to 0.898 (sufficient because DL only needs an approximation). The IU performance is assessed with 50% of the testing radiographs through the t test statistical method, obtaining p values of 0.0106 (line fitting) and 0.0213 (significant point detection). The IU performance is satisfactory, as these values are in accordance with the statistical average/standard deviation in pixels for line fitting (2.75/1.01) and for significant point detection (2.63/1.28) according to the expert criteria of dentists, who establish the ground-truth lines and significant points. In conclusion, AI methods have good prospects for automatic bone loss detection in intraoral radiographs to assist dental specialists in diagnosing peri-implantitis.
Cissus quadrangularis L extract-loaded tricalcium phosphate reinforced natural polymer composite for guided bone regeneration
Authors: Liao Lele , Zhu Weihong , Tao Cheng , Li Ding , Mao Minzhi 
Published: July 2023

AbstractNatural medicines plants are significant considerable attention as potential therapeutic agents for bone tissue engineering. Cissus quadrangularis L (CQ). is a potent therapeutic plant known for its own osteogenic properties. In this research work, a phytoconstituents-filled composite was produced by incorporating CQ extract with gelatin (Gel) and pectin (Pec) polymers collective through β- tricalcium phosphate (β-TCP) bioceramic via a green template method. The effect of CQ-filled composite morphology and chemical structural properties, in vitro cytotoxicity, cell proliferation, and differentiation was investigated. FTIR spectroscopic results indicated the prepared materials’ structural confirmation. The CQ extract was the alcoholic -OH merge with the hydroxyl and -NH groups in the range of 3000 cm−1 to 3500 cm−1. Scanning electron microscopy images showed that the β-TCP ceramic was perfectly embedded in Gel-Pec polymeric matrix, which is important for bone regeneration. In vitro cell culture results indicated that β-TCP/Gel-Pec/CQ composite provided 92.0% of a favorable substrate for mesenchymal stem cell viability. The gene expression and RT-PCR studies represent the materials with good osteogenic expression, especially the β-TCP/Gel-Pec/CQ composite is observed at 168.0% and 188.0% for RUNx2 and OCN, respectively. The result of the physicochemical characterizations and cell viability studies suggest that CQ-loaded β-TCP/Gel-Pec composite can serve as a potential biomaterial for bone tissue repair and regeneration.
Graphical Abstract
Kinematic and dynamic analysis of a 4-DOF over-constraint parallel driving mechanism with planar sub-closed chains
Authors: Huang Yangyang , Zhang Jinzhu , Xiong Xiaoyan , Liu Shengxiang 
Published: July 2023

AbstractIn this paper, a new over-constrained parallel driving mechanism (PDM) with planar sub-closed chains is proposed. First, the number of over-constraints on the PDM is calculated. Then, an analysis is conducted as to the kinematics of the hybrid manipulator, including positions, velocities, and accelerations of all bodies. Furthermore, the Newton–Euler approach is taken to deduce the kinematic formula of each link and the formula of inertial force at the center of mass. However, it remains difficult to solve the equation since the number of equations is smaller than that of unknown variables. To solve this problem, the screw theory is applied in the present study to analyze the cause of over-constraints, with the link’s elastic deformation introduced as the supplement of deformation compatibility equations. Moreover, the actuation forces and constrained forces/moments are calculated simultaneously. Finally, the dynamic model is verified through simulation and experimentation. The proposed modeling approach provides a fundamental basis for the structural optimization and friction force computation of the over-constrained PDM.
Retrospective evaluation of an integrated molecular-epidemiological approach to cyclosporiasis outbreak investigations – United States, 2021
Authors: Ahart Lauren , Jacobson David , Rice Marion , Richins Travis , Peterson Anna , Zheng Yueli , Barratt Joel , Cama Vitaliano , Qvarnstrom Yvonne , Montgomery Susan , Straily Anne 
Published: July 2023

Abstract
Cyclosporiasis results from an infection of the small intestine by Cyclospora parasites after ingestion of contaminated food or water, often leading to gastrointestinal distress. Recent developments in temporally linking genetically related Cyclospora isolates demonstrated effectiveness in supporting epidemiological investigations. We used ‘temporal-genetic clusters’ (TGCs) to investigate reported cyclosporiasis cases in the United States during the 2021 peak-period (1 May – 31 August 2021). Our approach split 655 genotyped isolates into 55 genetic clusters and 31 TGCs. We linked two large multi-state epidemiological clusters (Epidemiologic Cluster 1 [n = 136 cases, 54 genotyped] and Epidemiologic Cluster 2 [n = 42 cases, 15 genotyped]) to consumption of lettuce varieties; however, product traceback did not identify a specific product for either cluster due to the lack of detailed product information. To evaluate the utility of TGCs, we performed a retrospective case study comparing investigation outcomes of outbreaks first detected using epidemiological methods with those of the same outbreaks had TGCs been used to first detect them. Our study results indicate that adjustments to routine epidemiological approaches could link additional cases to epidemiological clusters of cyclosporiasis. Overall, we show that CDC’s integrated genotyping and epidemiological investigations provide valuable insights into cyclosporiasis outbreaks in the United States.
A high-resolution large-scale dataset of pathological and normal white blood cells
Authors: Bodzas Alexandra , Kodytek Pavel , Zidek Jan 
Published: July 2023

AbstractMicroscopic examination plays a significant role in the initial screening for a variety of hematological, as well as non-hematological, diagnoses. Microscopic blood smear examination that is considered a key diagnostic technique, is in recent clinical practice still performed manually, which is not only time consuming, but can lead to human errors. Although automated and semi-automated systems have been developed in recent years, their high purchasing and maintenance costs make them unaffordable for many medical institutions. Even though much research has been conducted lately to explore more accurate and feasible solutions, most researchers had to deal with a lack of medical data. To address the lack of large-scale databases in this field, we created a high-resolution dataset containing a total of 16027 annotated white blood cells. Moreover, the dataset covers overall 9 types of white blood cells, including clinically significant pathological findings. Since we used high-quality acquisition equipment, the dataset provides one of the highest quality images of blood cells, achieving an approximate resolution of 42 pixels per 1 μm.
Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism
Authors: Oya Masaki , Matsuoka Kiwamu , Kubota Manabu , Fujino Junya , Tei Shisei , Takahata Keisuke , Tagai Kenji , Yamamoto Yasuharu , Shimada Hitoshi , Seki Chie , Itahashi Takashi , Aoki Yuta Y. , Ohta Haruhisa , Hashimoto Ryu-ichiro , Sugihara Genichi , Obata Takayuki , Zhang Ming-Rong , Suhara Tetsuya , Nakamura Motoaki , Kato Nobumasa , Takado Yuhei , Takahashi Hidehiko , Higuchi Makoto 
Published: July 2023

AbstractIncreased excitatory neuronal tones have been implicated in autism, but its mechanism remains elusive. The amplified glutamate signals may arise from enhanced glutamatergic circuits, which can be affected by astrocyte activation and suppressive signaling of dopamine neurotransmission. We tested this hypothesis using magnetic resonance spectroscopy and positron emission tomography scan with 11C-SCH23390 for dopamine D1 receptors in the anterior cingulate cortex (ACC). We enrolled 18 male adults with high-functioning autism and 20 typically developed (TD) male subjects. The autism group showed elevated glutamate, glutamine, and myo-inositol (mI) levels compared with the TD group (p = 0.045, p = 0.044, p = 0.030, respectively) and a positive correlation between glutamine and mI levels in the ACC (r = 0.54, p = 0.020). In autism and TD groups, ACC D1 receptor radioligand binding was negatively correlated with ACC glutamine levels (r =  − 0.55, p = 0.022; r =  − 0.58, p = 0.008, respectively). The enhanced glutamate-glutamine metabolism might be due to astroglial activation and the consequent reinforcement of glutamine synthesis in autistic brains. Glutamine synthesis could underly the physiological inhibitory control of dopaminergic D1 receptor signals. Our findings suggest a high neuron excitation-inhibition ratio with astrocytic activation in the etiology of autism.
Emergence of topological and spin valley hallmarks in buckled Xene bilayers
Authors: Rahman Zia Ur , Rehman Majeed Ur , Kiani Maryam , Ullah Naeem 
Published: July 2023

Abstract
A subclass of two-dimensional materials with honeycomb structure, namely buckled Xene monolayers, are efficient for topological applications due to varying degrees of buckling in their lattice structure and have received a significant revival of interest in the last few years. However, to-date, less attention, as compared to, planer Xene bilayers has been assigned to the buckled Xene bilayers. The buckled Xene bilayers can offer a unique platform to study transport properties in bilayer systems. In this study, we explore the unknown topological behaviour of buckled Xene bilayers by exploiting the space inversion and time-reversal (TR) symmetries in these solids. In order to exploit the underline symmetries, we use light irradiation, layered antiferromagnetic exchange magnetization and vertical electric field as an external means. By mixing these three ingredients in a proper way, we achieve various topological phases in bilayers of buckled Xene solids, including TR-broken quantum spin Hall insulator, photo-induced quantum Hall insulator, photo-induced spin-polarized quantum Hall insulator, and quantum spin-valley Hall insulator. Furthermore, we establish a topological phase diagram and identify a topological domain wall in buckled Xene bilayers when subjected to circularly polarized light and gated voltage, which opens up possibilities for the propagation of perfectly valley-polarized channels.
Thermodynamic, transport, and radiation properties of HFO-1336mzz(E) mixtures as eco-friendly SF6 alternatives
Authors: Zhang Boya , Deng Junwei , Wang Sunsiqin , Cao Minchuan , Zhou Ran , Wang Guanyu , Li Xingwen , Tang Nian 
Published: July 2023

Abstract
HFO-1336mzz(E) is proposed as a novel alternative to SF6 due to its low greenhouse effect and high insulation strength. Typically, it is mixed with CO2 or Air to lower its boiling point to meet the minimum operating temperature. To better understand the thermophysical properties of the gases’ arcing plasma, the composition, thermodynamic properties, transport properties, and net emission coefficient of 30% molar fraction of HFO-1336mzz(E) mixed with CO2 or Air at temperatures from 300 K to 30 000 K at 0.12 MPa are calculated. It is found that HFO-1336mzz(E) mixtures have similar turbulent energy dissipation and thermal interruption capability to the pure SF6. Analysis of radiation characteristics demonstrates that the HFO-1336mzz(E) mixtures at 0.12 MPa exhibit stronger radiation emission compared to SF6 at 0.1 MPa, which indicates good arc radiation dissipation capabilities within such mixtures. This study reports the properties of thermal plasma of HFO-1336mzz(E) mixtures for the first time. These findings not only provide fundamental data for further magneto-hydro-dynamic calculations for arcing process but also put forward the potential application of these mixtures as arc interruption medium in medium voltage switchgears.
First-principles investigation of stable lead-free halide perovskite materials CsSnCl
x
Br
y
I3−x−y
for solar cell applications
Authors: Li Yaping , McKinney Lanie G , He Yuxuan , Liu Shi-Yu , Wang Sanwu 
Published: July 2023

Abstract
Perovskite solar cells based on hybrid organic–inorganic lead halide materials have attracted immense interest in recent years due to their enhanced power conversion efficiency. However, the toxic lead element and unstable property of the material limit their applications. With first-principles calculations based on density functional theory, we studied a series of ten lead-free perovskite materials made of cesium, tin, and halogen elements, chlorine (Cl), bromine (Br), and iodine (I). We found that the relative concentrations of the halogen atoms determine the crystal structures and the relative stability of the halide perovskites. Chlorine tends to increase the structural stability, while iodine plays the role of reducing the band gaps of the mixed halide perovskites. Considering the stability and the requirement of suitable band gaps, we identify that, among the ten lead-free halide perovskites, CsSnCl2I, CsSnBr2I, CsSnClBrI, CsSnClI2, CsSnBrI2, and CsSnI3 are the appropriate choices for solar cell applications.
Dimension measurement method of ring forgings based on laser scanning and multiple regression filtering algorithm
Authors: Lu Zheng , Zhou Qiwen , Zhang Yungang 
Published: July 2023

Abstract
In order to detect the radial is characterized and the isolated points that deviate from the target point cloud are removed using statistical section dimensions of ring parts in the forging process, we present a new method that processes laser scanning data of the outer radial section profile of ring forgings. Based on regression analysis and point cloud filtering, a multiple regression filtering algorithm is proposed to process the point cloud data for the measurement of the outer diameter of ring forgings. First, the laser scanned point cloud data filtering methods. The outlier clusters are then removed using regression analysis and processed by Gaussian regression filtering algorithms to obtain point cloud data with good circularity characteristics. Next, the Least Squares principle is used to fit a circle to the processed data to obtain information on the external diameter of the ring forgings to be measured. Finally, the feasibility of the method is verified by measuring the outer dimensions of the elliptical ring forgings in the experiment and performing error analysis.
On timing-optimized SiPMs for Cherenkov detection to boost low cost time-of-flight PET
Authors: Gundacker Stefan , Borghi Giacomo , Cherry Simon R , Gola Alberto , Lee Daehee , Merzi Stefano , Penna Michele , Schulz Volkmar , Kwon Sun Il 
Published: July 2023

Abstract

Objective. Recent SiPM developments and improved front-end electronics have opened new doors in TOF-PET with a focus on prompt photon detection. For instance, the relatively high Cherenkov yield of bismuth-germanate (BGO) upon 511 keV gamma interaction has triggered a lot of interest, especially for its use in total body positron emission tomography (PET) scanners due to the crystal’s relatively low material and production costs. However, the electronic readout and timing optimization of the SiPMs still poses many questions. Lab experiments have shown the prospect of Cherenkov detection, with coincidence time resolutions (CTRs) of 200 ps FWHM achieved with small pixels, but lack system integration due to an unacceptable high power uptake of the used amplifiers. Approach. Following recent studies the most practical circuits with lower power uptake (<30 mW) have been implemented and the CTR performance with BGO of newly developed SiPMs from Fondazione Bruno Kessler tested. These novel SiPMs are optimized for highest single photon time resolution (SPTR). Main results. We achieved a best CTR FWHM of 123 ps for 2 × 2 × 3 mm3 and 243 ps for 3 × 3 × 20 mm3 BGO crystals. We further show that with these devices a CTR of 106 ps is possible using commercially available 3 × 3 × 20 mm3 LYSO:Ce,Mg crystals. To give an insight in the timing properties of these SiPMs, we measured the SPTR with black coated PbF2 of 2 × 2 × 3 mm3 size. We confirmed an SPTR of 68 ps FWHM published in literature for standard devices and show that the optimized SiPMs can improve this value to 42 ps. Pushing the SiPM bias and using 1 × 1 mm2 area devices we measured an SPTR of 28 ps FWHM. Significance. We have shown that advancements in readout electronics and SiPMs can lead to improved CTR with Cherenkov emitting crystals. Enabling time-of-flight with BGO will trigger a high interest for its use in low-cost and total-body PET scanners. Furthermore, owing to the prompt nature of Cherenkov emission, future CTR improvements are conceivable, for which a low-power electronic implementation is indispensable. In an extended discussion we will give a roadmap to best timing with prompt photons.
Laser micro-fabricated multifunctional sensing layer for structural health monitoring
Authors: Li Zhenglin , Ding Taotao , Xiao Biao , Gao Yang , Xiang Yanxun , Xuan Fuzhen 
Published: July 2023

Abstract
Multifunctional sensing layer (MSL) integrated with multiple sensors and transducers has diverse applications in structural health monitoring (SHM). However, current MSLs still suffer from using rigid sensing units and complicated fabrication methods. To address this, a type of MSL integrated with flexible multi-functional sensing units and stretchable interconnectors was developed in this study by a laser-microfabrication (LMF) method with high efficiency and scalability. The flexible strain sensor has a sensitivity of 8.5, a minimum detection limit of 0.01%, and a durability of up to 12 000 cycles. The flexible temperature sensor has a temperature coefficient of resistance up to 2.75 × 10−3 °C–1 and a response time of 2.5 s. The flexible comb transducer provides a damage detection accuracy of over 90%. Further investigation proves the capability of the MSL for real-time monitoring of pressure vessels. The high efficiency and scalability of the LMF as well as the multi-functional sensing ability pave the potential application of the MSL in SHM.
Dynamic resistance and voltage response of a REBCO bifilar stack under perpendicular DC-biased AC magnetic fields
Authors: Sun Yueming , Geng Jianzhao , Badcock Rodney A , Jiang Zhenan 
Published: July 2023

Abstract
The dynamic resistance of REBCO (REBa2Cu3O7-d, RE stands for rare earth), coated conductors (CCs) is a key parameter in many high-temperature superconductor applications where CCs carry DC currents exposed to AC and DC magnetic fields, such as field-triggered persistent current switches, flux pumps, and fault current limiters. In this work, dynamic resistance and dynamic voltage have been studied via experiments and finite element method (FEM) simulations in a REBCO bifilar stack at 77 K, under combined AC and DC magnetic fields with different magnitudes, frequencies, and waveforms. Our results show some distinct features of dynamic resistance and voltage from those under pure AC magnetic fields. With an increasing DC magnetic field, the dynamic resistance exhibits an obvious linearity with the applied AC magnetic field, and becomes less dependent on the AC field frequency. The fundamental frequency of the dynamic voltage under a DC magnetic field becomes the same as that of the applied AC field, which completely differs from the pure AC field case where the fundamental frequency doubles. For the first time, instantaneous threshold field (B
th) values are obtained from the dynamic voltage, which are substantially different in the field-increasing and field-decreasing processes. These key differences are attributed to the dominant role of DC magnetic fields in determining the critical current of the superconductor, which significantly dwarfs the influence of AC fields. These new discoveries may help researchers better understand the electromagnetism of superconductors and be useful for relevant applications.