bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agility adaptability and alignment in start-ups
Authors: Sreenivasan Aswathy , Suresh M. 
Published: April 2023

Purpose
When coping with uncertainties, three characteristics distinguish firms: agility, adaptability and alignment (triple-A). Based on significant field research, the triple-A highlights the significance of coordinating agility, adaptability and alignment. Start-ups are facing a lot of challenges in this turbulent environment. However, this sector is undergoing a major transformation. Agility, adaptability and alignment concepts have had a major influence on the supply chain, but their implementation in start-ups has been less visible. This paper aims to identify, analyze and categorize the enablers for agility, adaptability and alignment in start-ups using the total interpretive structural modeling (TISM) approach.

Design/methodology/approach
In addition to the scheduled interview, a closed-ended questionnaire was used to collect data. To identify how the factors interact, the TISM technique is used, and the Matriced’Impacts Croises-Multipication Applique’ and Classment method is used to rank and categorize the agility, adaptability and alignment enablers.

Findings
This study identified ten agility, adaptability and alignment factors for start-ups. It has been found that the key importance should be given to management involvement, conflict management, collaboration and information integration.

Research limitations/implications
This study primarily focused on the agility, adaptability and alignment factors in start-ups.

Practical implications
This study will help academics and key stakeholders understand the aspects that lead to agility, adaptability and alignment in start-ups.

Originality/value
Agility, adaptability and alignment concepts have had a major influence on the supply chain, but their implementation in start-ups has been less visible. Therefore, this is a novel attempt in this industry’s agility, adaptability and alignment.
Drug abuse and suicidal thoughts among employees: an emerging economy perspective
Authors: Amponsah-Tawiah Kwesi , Lartey Joshua King Safo , Suleman Abdul-Razak 
Published: April 2023

PurposeAnchored with turbulence emanating from the COVID-19 pandemic, the work environment has become more stressful with debilitating effects on the well-being of employees. Employees rely on varying means of coping including drug abuse. However, the association between drug abuse and suicidal thoughts among employees in Ghana is unknown. Therefore, this study sought to examine the relationship between drug abuse and suicidal thoughts among employees in Ghana.Design/methodology/approachIn a cross-sectional survey, this study purposively sampled 470 employees from three sectors of the Ghanaian economy (telecommunication, banking and manufacturing). The data was analysed using the multivariate analysis (MANOVA), Pearson’s r test and hierarchical regression.FindingsAnalysis of data revealed a positive relationship between drug abuse and suicidal thoughts, indicating that drug abuse is a risk factor for suicidal thoughts. Besides, it was also revealed that banking sector employees have a higher risk of having suicidal thoughts than employees in the telecommunication and manufacturing sectors.Practical implicationsManagers of organisations need to redesign work to embrace the challenging circumstances brought about as a result of COVID-19 and post-COVID implications. The work environment needs to be more supportive to shield employees from the physical and emotional demands of work during and after this period of the COVID-19 pandemic. Today than ever, investment in the implementation of employee-assisted programmes (EAPs) and employee well-being programmes (EWPs) to equip employees with the needed skills to cope with stressful conditions has been more than justified.Originality/valueFrom a broader perspective, this study identifies drug abuse as a key risk factor for suicidal thoughts among employees, thereby highlighting the fact that smoking cessation programs and drug management therapies are an integral part of well-being programmes aimed at establishing equilibrium and gradually creating a wide gap between employees and suicidal thoughts.
Exploring the domain of relationship between happiness management in organizations and the environment
Authors: Rando Cueto Dolores , Jambrino-Maldonado Carmen , Jiménez-Marín Gloria , Iglesias-Sánchez Patricia P. 
Published: April 2023

PurposeOrganizational happiness has received exponential attention in recent years. To offer an over-view for future research gap, this article produces a comprehensive review by combining bibliometric analysis and interviews to key authors in the field. The main objective of this paper is to show the state of research regarding the environment in the management of happiness in organizations: the evolution of scientific activity, current trends in authorship, topics and future setting research agenda.Design/methodology/approachThe methodological process focuses on a mixed method. A systematic review of the relevant literature; bibliometric analysis and network mapping in the Web of Science and Scopus data-bases; bibliometric network analysis of authorship, citation and co-occurrence of key words in scientific publications.FindingsThe results reveal that happiness management is gaining importance and, moreover, more than half of the publications about happiness management are related to the environment in which the organizations are immersed. Therefore, the study provides some research directions and insists on role of environment to better understand the theoretical and practical perspectives. Likewise, bibliometric analysis and interviews allow to measure quality, impact, productivity and scientific evolution which are increasingly valued in order to identify the main concepts and topics that are considered key, drivers of research and those gaps that should be addressed in future research work for the conceptual framework of happiness management in organizations.Originality/valueConclusions are drawn that promoting corporate social responsibility strategies, aimed at fostering sustainability and care for the environment result in the well-being of organizations and the performance of their workers are highlighted.
Trafficking trauma: a review on the psychological effects of human trafficking
Authors: Pascale Raluca Ioana , Tzani Calli , Ioannou Maria , Williams Thomas James Vaughan , Hunt Daniel 
Published: April 2023

Purpose
The purpose of this study is to investigate the psychological consequences of human trafficking and to reveal the importance of appropriate post-trafficking psychological interventions. Specifically, this study provides a detailed analysis of human trafficking categories, as well as the characteristics of victims and traffickers’ motives. More recent data in the literature show that trauma-coerced attachments and complex post-traumatic stress disorder are also observed among trafficking survivors.

Design/methodology/approach
Each of the mentioned mental disorders is presented separately, and results are discussed throughout this study. Consequently, psychological interventions are proposed in accordance with the human trafficking category, survivors’ characteristics and needs and with the relevant personal risk factors determined among victims.

Findings
Sex trafficking can have a severe effect on a victim’s mental health, and mental health disorders are substantially higher in human trafficking victims compared to non-trafficked victims or general psychiatric population. Limitations, implications and future recommendations are discussed.

Originality/value
A limited number of past studies evaluated the mental health consequences and identified that survivors have a higher prevalence of anxiety disorders, depression disorders and post-traumatic stress disorder.
How does the hospitality industry integrate heritage?
Authors: Munjal Parul G. 
Published: April 2023

PurposeThe paper aims to highlight the importance of nurturing heritage from the perspective of hospitality professionals and entrepreneurs in countries such as India that have a wealth of natural and cultural heritage resources. The intent is to bring out intersections of heritage and hospitality and place these in the context of global and local issues and concerns.Design/methodology/approachHeritage has been outlined in a broad and inclusive manner, to include not only tangible natural and cultural resources but also intangible oral histories, processes and practices embedded in traditional knowledge. Secondary sources are used to represent trends mapped in other studies though the main narrative is derived from gaps and opportunities observed by the author, both as a heritage expert and consumer of heritage hospitality.FindingsThere are three areas where the hospitality industry intersects with heritage in the current context, namely, awareness of heritage resources and integration of these in curating creative visitor experiences, incorporating traditional sustainable practices in the operating procedures of hospitality services, and in fostering heritage entrepreneurship.Originality/valueThis viewpoint should be of interest to researchers, academics and practitioners with a hospitality background as they seek creative ways of bringing heritage and traditional knowledge into mainstream hospitality education and practice, based on more systematic inquiry and exploration.
Mechanisms and consequences of infection‐induced phenotypes
Authors: Nadler Lauren E. , Adamo Shelley A. , Hawley Dana M. , Binning Sandra A. 
Published: April 2023

AbstractResearchers studying animal phenotypes often overlook the potential influence of parasites hiding inside their study organisms. Yet, most wild animals host parasites, which can alter individual phenotypes (e.g. morphology, physiology, behaviour).Infection‐induced phenotypes stem from several nonmutually exclusive mechanisms (i.e. adaptive host defences, infection‐induced debilitation and host manipulation by parasites), driven by parasites and/or hosts.Changes in host phenotype can impact all levels of biological organization, from cells to communities. The nature and magnitude of these effects can vary depending on the biotic and abiotic environmental factors experienced by hosts and parasites.This special feature highlights recent insights into the ways parasites alter host phenotypes across a range of systems. Here, we contextualize how each contribution expands our knowledge of the role of parasites in driving individual variation in animal phenotypes.Looking to the future, we need to better understand how infection‐induced phenotypes fluctuate with natural variation in infection (e.g. infection intensity, coinfection) and whether studies in laboratory‐based environments provide strong proxies for host–parasite interactions in the wild. The time is ripe to acknowledge, critique and discuss the implications of infection on host phenotypes across taxonomic boundaries and biological levels of organization.Read the freePlain Language Summaryfor this article on the Journal blog.
Hiding in plain sight: IDP's protection strategies after closing Juba's protection of civilian sites
Authors: Janguan Tot , Kirk Tom 
Published: April 2023

AbstractThis article examines how former Protection of Civilian site (PoCs) residents are staying safe and protecting themselves after the United Nations Mission in South Sudan's (UNMISS) handing over of the PoCs to the Revitalised‐Transitional Government of National Unity (R‐TGoNU). Using key informant interviews, questionnaires, and observations, we establish that those still residing in the PoCs do so with less humanitarian assistance, increased insecurity, and few authorities they can rely upon or turn to for protection. In response, it is shown how camp residents have developed their own safety and protection strategies at the cost of their ability to pursue livelihoods, move freely outside of the camps, and publicly express their identities. Although broadly stable, this situation is unsustainable and risks the safety of camp residents and the wider ongoing peace process. The paper concludes with policy recommendations for humanitarians and R‐TGoNU policymakers interested in their welfare.
Osimertinib combined with bevacizumab as the first‐line treatment in non‐small cell lung cancer patients with brain metastasis harboring epidermal growth factor receptor mutations
Authors: Zhang Ling , You Yunhong , Liu Xueli , Liu Fengjuan , Nie Keke , Ji Youxin 
Published: April 2023

AbstractBackgroundThe efficacy and safety of osimertinib combined with bevacizumab in non‐small cell lung cancer (NSCLC) patients with brain metastasis harboring epidermal growth factor receptor (EGFR) mutations have not been fully studied.MethodsTreatment‐naïve NSCLC patients with brain metastasis harboring EGFR‐activating mutations were treated with osimertinib 80 mg oral daily and bevacizumab 15 mg/kg intravenously on day 1, repeated every 21 days, until disease progression, intolerable toxicity, or death. The primary endpoint was the median progression‐free survival (mPFS), and the secondary endpoints were the median overall survival (mOS), response rates, and toxicities. This study has been registered in ClinicalTrials.gov (NCT05104281) and is ongoing.ResultsA total of 52 Chinese patients were enrolled, of whom 17 harbored EGFR 19 del and 35 harbored EGFR L858R mutation. The objective response rate (ORR) was 75.0% and the disease control rate (DCR) was 96.2%; the mPFS was 17.0 months (95% CI: 11.46–22.54), while the mOS was not reached. The mPFS was 20.0 months (95% CI: 14.56–25.44) and was 17.0 months (95% CI: 13.28–20.72) for patients harboring EGFR 19 del and EGFR L858R mutation (p = 0.844), respectively. The intracranial ORR was 82.7%, and the intracranial mPFS was 22.0 months (95% CI: 2.92–41.08).The main adverse events were mild‐to‐moderate hand‐foot syndrome, diarrhea, hypertension, and proteinuria. Three patients developed grade III proteinuria, while five patients developed grade III hypertension; they permanently discontinued bevacizumab treatment.ConclusionsOsimertinib combined with bevacizumab shows promising results in EGFR‐mutated NSCLC patients with brain metastasis, and the side effects are tolerable.
Estimating the effect of time‐invariant characteristics in panel data: wheat adoption in Western Canada
Authors: Syme Jennifer , An Henry , Torshizi Mohammad 
Published: April 2023

AbstractA growing global population and the challenges of climate change have made the need to develop new and improved wheat varieties increasingly important. Creating varieties that are more disease resistant and tolerant to changing environmental conditions such that they will be widely adopted requires breeders to understand the needs of producers. Existing literature suggests that time‐invariant traits such as disease resistance and brand matter in crop adoption decisions; however, studies using common panel data approaches are unable to identify the individual effects of time‐invariant variables, as they are captured by fixed effects dummies. This study uses a recently developed econometric approach—the fixed effects filter model—that can estimate the effects of time‐variant, slowly changing, and time‐invariant traits. Using wheat variety adoption in the Canadian Prairies as our empirical setting, we find that both time‐variant traits, such as varietal adaptability, and time‐invariant traits, such as resistance to stripe rust infection, are positively correlated with adoption. We also find that seed brand has a statistically significant effect on adoption. Prior panel data studies on crop adoption have not given much consideration to time‐invariant variety characteristics like disease tolerance and seed brand, but a better understanding of their impact on adoption can assist breeders in responding to emerging problems, particularly new diseases, more quickly and more efficiently. This will also enhance the work by crop research institutions, prevent considerable economic loss to farmers, and improve crop production.
Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis
Authors: Semmler Georg , Scheiner Bernhard , Balcar Lorenz , Paternostro Rafael , Simbrunner Benedikt , Pinter Matthias , Trauner Michael , Bofill Roig Marta , Meyer Elias Laurin , Hofer Benedikt Silvester , Mandorfer Mattias , Pinato David James , Zauner Christian , Reiberger Thomas , Funk Georg‐Christian 
Published: April 2023

SummaryBackgroundHyponatremia has prognostic implications in patients with cirrhosis, and thus, has been incorporated in the 2016 MELD‐UNOS update. Changes in serum chloride are commonly perceived as ‘just’ parallel to changes in serum sodium. However, these are less well studied in the context of cirrhosis.AimsTo investigate whether serum chloride independently predicts outcomes in patients with advanced chronic liver disease (ACLD) and stable clinical course or with critical illness.Methods891 patients with ACLD (defined by hepatic venous pressure gradient [HVPG] ≥6 mm Hg) were followed after HVPG measurement between 2003 and 2020 (ACLD cohort). 181 critically ill patients with cirrhosis admitted to the ICU between 2004 and 2007 were recruited for the ICU cohort. Hypo−/hypernatremia (normal: 136–145 mmol/L) and hypo−/hyperchloremia (normal: 98–107 mmol/L) at baseline were assessed.ResultsACLD cohort: 68% of male patients with a median MELD (adjusted for Na) of 11 (9–17) were included (Child‐Pugh‐stages‐A/B/C: 46%/38%/16%) and followed for a median of 60 months. Lower serum chloride (adjusted average HR per mmol/L: 0.965 [95% confidence interval (95% CI): 0.945–0.986], p = 0.001) showed a significant association with hepatic decompensation/liver‐related mortality on multivariable Cox regression analysis adjusted for age, HVPG, albumin and MELD. In line, hypochloremia was significantly associated with hepatic decompensation/liver‐related mortality (adjusted average HR: 1.656 [95% CI:1.267–2.163], p < 0.001).ICU cohort: 70% of patients were male, median MELD was 31(22–39) at ICU admission (92% with Child‐Pugh‐stage‐C). After adjusting for hypo−/hypernatremia, MELD, and blood pH, hypochloremia remained independently associated with ICU‐mortality (aOR Cl: 3.200 [95%CI: 1.209–8.829], p = 0.021).ConclusionHypochloremia is associated with increased mortality in clinically stable and critically ill patients with cirrhosis independently of MELD including serum sodium.
Interacting with global refugee complexity and wresting control: Shan refugees and migrants in Thailand
Authors: Nillsuwan Benjamas 
Published: April 2023

AbstractThe changes in Thailand's policy on labor migrant control appeared optimistic for refugee and human rights issues in recent years. This article argues that such positive adjustment is to take control of refugees and migrants outside the space of the global refugee regime. Using the case of Chiang Mai, Thailand, it discussed how the movement of Shan people in this area indicates mixed migration and how the Thai authorities and local Thais' views of them affect their status in Thailand. It examined the role of international norms that influence Thailand's policy and treatment of the Shan refugees and migrants in education and healthcare. Recent adjustments demonstrated that the Thai government began altering migration restrictions, although this is an attempt to seize control. In the refugee regime complexity, Thailand interacts with the regimes in two areas: education and healthcare, to maintain the control and manageability of refugees and migrants.
Vascular closure devices in living‐donor nephrectomy: a much‐needed systematic review and meta‐analysis focusing on safety
Authors: Burgos Revilla Francisco Javier , Artiles Medina Alberto , Domínguez Gutiérrez Ana , Muriel García Alfonso , Figueiredo Arnaldo , Gómez Dos Santos Victoria 
Published: April 2023

ObjectiveTo assess the safety of vascular closure devices in living‐donor nephrectomy (LDN), as staplers and non‐transfixion techniques (polymer locking and metal clips) are the methods employed to secure the renal vessels during laparoscopic and robotic LDN, but the use of clips has come into question since the United States Food and Drug Administration and manufacturers issued a contraindication.MethodsA systematic review and meta‐analysis were conducted to assess the safety of vascular closure devices (International Prospective Register of Systematic Reviews [PROSPERO] registration: CRD42022364349). The PubMed, Scopus, the Excerpta Medica dataBASE (EMBASE), and the Literatura Latino‐Americana e do Caribe em Ciências da Saúde (LILACS) databases were searched in September 2022. For comparative and non‐comparative studies, incidence estimates and odds ratios (ORs), respectively, for the main variables regarding safety of vascular closure devices were pooled by using random effects meta‐analyses. Quality assessment of the included comparative studies was conducted using the Risk Of Bias In Non‐randomised Studies of Interventions (ROBINS‐I) tool.ResultsOf the 863 articles obtained, data were retrieved from 44 studies, which included 42 902 patients. In non‐comparative studies, the pooled estimate rates for device failure, severe haemorrhage rate, conversion to open surgery, and mortality were similar for both clips and staplers. Regarding the meta‐analyses for comparative studies (three studies), there were no significant differences between the two groups for the severe haemorrhage rate (OR 0.57, 95% confidence interval [CI] 0.18–1.75; P = 0.33), conversion to open surgery (OR 0.35, 95% CI 0.08–1.54; P = 0.16), or death rate (OR 3.64, 95% CI 0.47–28.45; P = 0.22). Based on weak evidence, device failure was lower in the polymer clip group (OR 0.41, 95% CI 0.23–0.75; P = 0.00).ConclusionsThis study has confirmed that there is no evidence for the superiority of any vascular closure device in terms of safety in LDN. Standardised recommendations for vascular control in this context should be carefully designed and prospectively evaluated.
Characterising the internal structural complexity of the Southern North Sea Zechstein Supergroup Evaporites
Authors: Barnett Hector G. , Ireland Mark T. , Van der Land Cees 
Published: April 2023

AbstractThe internal structure and architecture of evaporite sequences is often overlooked, with attention frequently concentrating on the external geometries that salt bodies form. The availability of extensive 3D seismic data affords the opportunity to interpret the internal structures within these evaporite sequences and comprehensively characterise the different structural facies over large areas. This paper concentrates on the Zechstein Supergroup evaporite deposits within the Southern North Sea of the United Kingdom's Continental Shelf. This analysis of the internal structural complexity and stratigraphic heterogeneity utilises 26,000 km2 of 3D seismic data together with over 96 wells from the Southern North Sea. Characterisation of the different structural facies present was undertaken alongside mapping their spatial distribution to understand the relationship they have with one another and the structural evolution that may have been taken. This work has (1) characterised and mapped six different internal structural facies present within the Zechstein with increasing levels of deformation; (2) shown the internal lithological heterogeneity is indicative of variations in the vertical strength profile of layered evaporite sequences; (3) discontinuous high‐amplitude reflections within the Zechstein are as a result of the geometries being too steeply dipping for the seismic data to image; and (4) the ability to possibly predict the internal heterogeneity of areas of poorly imaged salt, such as within large diapiric salt structures, from surrounding structural facies. These findings suggest that there is significant internal complexity even within areas of the basin with minor mobilisation to the external salt geometry.