bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ketahanan Keluarga dalam Adaptasi New Normal Pandemi Covid-19 di Indonesia
Authors: Roma Megawanty  , Margaretha Hanita  
Published: February 2023

Ketahanan keluarga adalah elemen utama dalam menghadapi kerentanan terhadap guncangan dari luar, baik guncangan kecil, sedang maupun besar. Pandemi Covid-19 yang melanda dunia sejak Januari 2020 adalah guncangan besar yang dalam waktu singkat mengubah dunia ke arah kerusakan: kematian, kehancuran ekonomi, kepanikan dan kekacauan. Lockdown diterapkan di mana-mana di seluruh dunia yang menghasilkan dua dampak : mengurangi jumlah orang terinfeksi namun di sisi sebaliknya semakin memperparah kerusakan ekonomi dan sosial. WHO menyarankan dunia menerapkan New Normal, kondisi di nama kehidupan dijalankan seperti sediakala namun dengan cara yang berbeda. Berhasil atau tidak berhasilnya New Normal bergantung pada seberapa lenting ketahanan keluarga beradaptasi menghadapi guncangan besar.
PENGARUH KUALITAS PRODUK DAN PELAYANAN TERHADAP KEPUASAN KONSUMEN (STUDI PADA CARREFOUR LEBAK BULUS - JAKARTA)
Authors: Tarmizi Achmad 
Published: February 2023

Costumer satisfaction is the main for hypermarket employees to give the best quality of service. Then every costumer wants to expense more for service quality which can make happy the customer to be served as at their home. Customer service could be seen after the customers use the product of service. With other word, customer satisfaction is after service evaluation or evaluation after comparing what they feel with their hope. The research aim is to know “product quality affect and service quality to customer satisfaction (Study on Carrefour of Lebak Bulus, Jakarta.
The research result show that affect variable of product quality and service quality affect significantly to customer satisfaction of Carrefour of Lebak Bulus. T test result take thitung value accepted at 5% significant, quality service variable affects dominantly to customer service comparing with product quality variable. T test result take thitung value for quality service variable (7.444) more than thitung value product quality variable (3.308) at significant of 5%.
Pengaruh Religiusitas, Pelayanan, dan Promosi terhadap Keputusan Menabung Di Bank Syariah
Authors: Nadya Maulina Robyani  , Ritonga Ahmad Husein , Mubyarto Novi 
Published: February 2023

Artikel ini membahas tentang pengaruh religiusitas, pelayanan, dan promosi terhadap keputusan menabung di Bank Syariah, di mana lokasi penelitiannya adalah Bank Syariah di Pasar Angso Duo Jambi. Masalah utama dalam penelitian ini adalah mengapa masih banyak pedagang yang tidak menggunakan jasa menabung di Bank Syariah Indonesia? Penelitian ini merupakan penelitian Kuantitatif Deskriptif dengan metode survey dengan menggunakan analisis jalur (Path analysis). Penelitian ini menemukan bahwa Religiusitas berpengaruh signifikan terhadap minat menabung di Bank Syariah. Pelayanan berpengaruh signifikan terhadap minat menabung di Bank Syariah. Promosi tidak berpengaruh terhadap minat menabung di Bank Syariah. Religiusitas berpengaruh signifikan terhadap keputusan menabung di Bank Syariah. Pelayanan tidak berpengaruh signifikan terhadap keputusan menabung di Bank Syariah. Promosi tidak berpengaruh signifikan terhadap keputusan menabung di Bank Syariah. Minat berpengaruh signifikan terhadap keputusan menabung di Bank Syariah. Religiusitas dan pelayanan secara tidak langsung melalui minat menabung berpengaruh signifikan terhadap keputusan menabung di Bank Syariah dan terjadi efek mediasi. Sedangkan promosi secara tidak langsung melalui minat menabung tidak berpengaruh signifikan terhadap keputusan menabung di Bank Syariah dan tidak terjadi efek mediasi.
Clinical application of the principles of weaning from invasive ventilation in very preterm infants
Authors: Миткинов Олег Эдуардович , Дашибалов Абида Ашагнимаевич 
Published: February 2023

Пролонгированная искусственная вентиляция легких связана с повышением риска развития бронхолегочной дисплазии и неблагоприятных неонатальных исходов. Ранняя экстубация является желаемым вариантом терапии, но опасна преждевременная и неподготовленная экстубация. Исследованы случаи экстубации у 146 новорожденных с гестационным возрастом менее 27 недель (57 детей) и 27-31 неделя (89 детей). Применены критерии готовности к экстубации и методы неинвазивной вентиляции с перемежающимся положительным давлением и высокочастотной осцилляторной вентиляции. Частота вынужденной реинтубации в течение 5 суток после экстубации составила 21-22%.
Mechanical ventilation in newborns increases the risk of bronchopulmonary dysplasia and poor neontal outcomes. Early extubation is a desirable treatment option, but premature and unprepared extubation is dangerous. Extubation was performed in 146 newborns with a gestational age of less than 27 weeks (57 children) and 27-31 weeks (89 children). Extubation readiness criteria and non invasive intermittent positive pressure ventilation and high frequency oscillatory ventilation were applied. The frequency of forced reintubation within 5 days after extubation is at the level of 21-22%.
THE USE OF NON-INVASIVE VENTILATION AND HIGH-FLOW OXYGEN THERAPY IN CHILDREN WITH VARIOUS PATHOLOGIES IN THE INTENSIVE CARE UNIT OF A MULTIDISCIPLINARY HOSPITAL
Authors: Лебедева Елена Александровна , Никитина Надежда Владимировна , Шаршов Федор Геннадьевич , Смыков Артем Юрьевич , Шарнина Анастасия Дмитриевна 
Published: February 2023

В исследовании приведен анализ частоты применения неинвазивной вентиляции легких через назальные канюли, лицевую маску, шлем у 98 детей с различной патологией, а также сложности в их применении. В ходе работы были исследованы режимы подбора неинвазивной вентиляции, возрастные группы пациентов, эффективность применения данного метода. Несмотря на достаточно большое число сложностей, высокопоточная оксигенотерапия и неинвазивная вентиляция легких активно используются при лечении дыхательной недостаточности во всех возрастных группах. Как показал анализ, неинвазивная вентиляция с помощью шлема у детей младше 3 лет не проводилась. Данный факт, вероятно, связан с необходимостью проведения дополнительной седации, сложностями с доступом к дыхательным путям ребенка, подбором параметров для достижения оптимального режима и образованием конденсата. Частота применения высокопоточной оксигенотерапии и неинвазивной вентиляции легких при лечении острой дыхательной недостаточности у детей всех возрастов составляет более 79% при различной патологии. Ограниченное использование шлема для проведения неинвазивной вентиляции требует более детального анализа.
The study analyzes the frequency of noninvasive lung ventilation through nasal cannulas, face mask, helmet in 98 children with various pathologies, as well as difficulties in their use. In the course of the work, the modes of selection of noninvasive ventilation, age groups of patients, and the effectiveness of this method were investigated. Despite a rather large number of difficulties, high flow oxygen therapy and non invasive ventilation are actively used in the treatment of respiratory failure in all age groups. As the analysis showed, noninvasive ventilation with a helmet was not performed in children under 3 years of age. This fact is probably related to the need for additional sedation, difficulties with access to the respiratory tract of the child, the selection of parameters to achieve the optimal regime and the formation of condensation. The frequency of high flow oxygen therapy and noninvasive ventilation in the treatment of acute respiratory failure in children of all ages is more than 79% in various pathologies. The limited use of the helmet for non invasive ventilation requires a more detailed analysis.
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДА КОНТРЕЙЛЕРЛІК ТАСЫМАЛДАУ ТЕХНОЛОГИЯСЫН ҚОЛДАНУ АРҚЫЛЫ ЛОГИСТИКАЛЫҚ ИНФРАҚҰРЫЛЫМНЫҢ ТИІМДІЛІГІН ӘЗІРЛЕУ
Authors: КАСЕНБАЕВА З.У. , ТЛЕУКЕЕВА А.Т. , НУРМУХАНБЕТОВА И.Ж. , КРУНКЕЕВА И.А. 
Published: February 2023

В статье рассмотрены вопросы развития транспортно-логистической инфраструктуры автомобильного транспорта в Республике Казахстан. Предложено решение по совершенствованию логистической инфраструктуры в стране, путем использования такой технологии, как контрейлерные перевозки.
Мақалада Қазақстан Республикасында автомобиль көлігінің көліктік-логистикалық инфрақұрылымын дамыту мәселелері қаралды. Контрейлерлік тасымалдар сияқты технологияларды пайдалану арқылы елдегі логистикалық инфрақұрылымды жетілдіру бойынша шешім ұсынылды.
The article deals with the development of transport and logistics infrastructure of road transport in the Republic of Kazakhstan. A solution has been proposed to improve the logistics infrastructure in the country by using space technology as piggyback transportation.
Study on Determinants of Capital Structure in the Pharmaceutical Industry of Pakistan
Authors: Haque Zia ul , Shaiq Muhammad 
Published: February 2023

This research on the determinant of capital structure is limited to pharmaceutical companies listed on Pakistan Stock Exchange (PSX). Several researchers both in developed and developing countries have attempted to identify determinant of capital structure for different industries in their economies. The results for various explanatory variables used by researchers have been somewhat mixed. Some of the variable which were found significant in explaining the capital structure in one study remained insignificant in the other studies. This empirical study makes an attempt to explore the determinants of capital structure in the pharmaceutical firms quoted on PSX (Pakistan Stock Exchange). This study coversa ten years period from 2012 to 2021( both inclusive) for seven companies using eleven explanatory variables for leverage. There are twelve companies listed on PSX, seven of these twelve quoted companies on the basis of availability of data for all 10 years have been selected. The results of the study indicate, operating leverage, firm’s specialty, return on asset and tax rate were significant determinants of capital structure. It was also observed that the size of the firm, growth rate, basic earning power, fixed charges coverage ratio, non-debt tax shield, dividend payout ratio and liquidity have a minor (insignificant) influence on the capital structure of the pharmaceutical companies in Pakistan.
Efektivitas Penerapan Sistem E-Court Pengadilan Agama Dalam Perkara Perceraian
Authors: Shodikin Akhmad , Saepullah Asep , Lestari Imas Indah 
Published: February 2023

Fast traslate Icon translate Fast traslate Icon translate Fast traslate Icon translate E-court is a court instrument as a form of service to the community in terms of online case registration, online payment, sending trial documents (answers, replicates, duplicates and conclusions) and online summons, the e-court application is expected to improve services in its function of receiving online case registration where the public will save time and money when registering a case.This study aims to answer questions from the formulation of the problem: "how is the application of the e-court system in divorce cases at the Cirebon City Religious Court", "What is the impact of the application of the e-court system in the Religious Court of Cirebon City for the community seeking justice" The research methodology uses a qualitative research methodology, namely research methods based on original data sources, both textually and non-textually.The results of this study: the application of the use of the e-court application in divorce cases, namely after the plaintiff received an electronic call, then an electronic trial was carried out in the trial of the plaintiff and the defendant agreed to conduct an electronic trial by filling in the principal agreement, so the parties could do it according to e-summons to The trial schedule has been integrated with the SIPP trial postponement, for the control mechanism (receiving, checking and forwarding) of all uploaded documents as long as they have not been verified by the judge the parties cannot download the documents sent. The e-court system brings smoothness, convenience and success to its users because with the e-court application, parties do not need to come to the court so that it does not incur transportation costs and it can be more efficient in time spent. Effectiveness of divorce case e-court, Religious Court
Association between androgen receptor gene alteration and osteoporosis in Chinese Han elderly men
Authors: Huang Xin , Zhang Zhengdong , Zou Liangxuan , Li Wenbo , He Jun 
Published: February 2023

Objective
To explore the role of blood glucose, blood lipids, and androgen receptor gene (CAG)n genotype in the pathogenesis of osteoporosis in Chinese Han men and to provide theoretical value for screening people susceptible to osteoporosis.

Methods
Patients who visited the First Affiliated Hospital of Chengdu Medical College from February 2021 to October 2021 were selected as research subjects to measure bone density by double-energy X-ray, osteoporosis patients as osteoporosis group (40 patients), and non-osteoporosis patients as the control group (40 patients). The STR method detected the repeat times of the androgen receptor gene (CAG)n in the two groups. The repeat times ≤22 were the SS genotype, and >22 were the LL genotype. Meanwhile, the patient’s age, body mass index (BMI), blood glucose, blood lipids, calcium, phosphorus, and alkaline phosphatase examined on day one after admission were collected, and the statistical analysis was performed using SPSS 26.0.

Results
The results of the univariate analysis showed that there was no significant difference in age, calcium, phosphorus, alkaline phosphatase, and glycosylated hemoglobin between the two groups (P > 0.05). There were significant differences in average blood glucose, total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, and genotype frequency (P < 0.05). The multivariate logistic regression analysis results showed significant differences in total cholesterol and genotype frequency between the two groups (P < 0.05).

Conclusion
Androgen receptor LL genotype and elevated total cholesterol may be the risk factors for osteoporosis in older men of Han nationality.
Tsallis’ Analysis of the Horizontal Component of the Earth’s Magnetic Field over India during 2002
Authors: Jayapal R. , Anilkumar C. P. , Unnikrishnan K. , Venugopal Chandu 
Published: February 2023

A widely used measure of entropy to quantify uncertainity in an open system is the Boltzmann-Gibbs (B-G) entropy. It, however, cannot describe non-equilibrium systems with large variability and multi-fractality. A generalisation of the B - G entropy is the Tsallis’ entropy. The values of the horizontal components of the Earth’s magnetic field, observed at various stations in India in 2002 were used. During the years 2000 – 2002, solar cycle 23 reached its maximum. Data from Ettaiyapuram (ETT, latitude = 90 10’ N, longitude = 780 01’ E, geomagnetic latitude = 0.130 N), Visakhapatnam (VIS, 170 41’ N, 830 19’ E, 8.170 N), Hyderabad (HYD, 170 25’ N, 780 33’ E, 8.170 N), Alibag (ABG, 180 37’ N, 720 52’ E, 10.020 N) and Tirunelveli (TVI, 80 42’ N, 770 48’ E, 0.320 S) were used. Using these values as inputs, we demonstrate that Tsallis’ entropy can be used to detect minor differences in the horizontal components of the geomagnetic field observed between different pairs of stations. The method is a very simple and elegant one to detect minor variations between pairs of similar signals.
A Novel Dual-wavelength, Dual-function Laser System for Presbyopia and Glaucoma Treatments
Authors: Lin Jui-Teng 
Published: February 2023

Purpose: To update the accommodation mechanisms and propose a dual-wavelength, dual-function laser system for presbyopia and glaucoma treatments.
Study Design: Laser sclera softening (LSS) for increased accommodation of presbyopic eyes.
Place and Duration of Study: New Taipei City, Taiwan, between Jan., 2023 and Feb., 2023.
Methodology: Accommodation gain (AG) can be improved by: (i) thermal shrinkage of the scleral stroma and ciliary body, or (ii) softening of the scleral stroma (with temperature range of 700C to 900C), such that the the lens front and back curvature change (or lens thickening), leading to the thickening of ciliary body and its apex, and the increase of the space of ciliary body and lens equation (SCL), and the length of the posterior vitreal zonules (PVZ) increases.
Results: A novel dual-color laser system having wavelength A and B, acting on the front-zone and back-zone of the sclera, respectively, where laser-A has a deep thermal penetration the sclera and ciliary body (CB) (0.5 to 1.0 mm); and laser-B has a shallow penetration depth in the sclera (0.3 to 0.5 mm), based on the optical property of the sclera. Laser-A (having a wavelength about0.8 to 0.98 um) leads to thermal shrinkage of the ciliary body such that the CLS is increased for accommodation gain which is much more effective than the prior art.
Conclusion: The increase of AG can be achieved by scleral softening and ciliary body shrinkage which increase the SCL. A proposed novel dual-color laser system acting on the front-zone and back-zone of the sclera, respectively, could provide higher AG than that of single wavelength, or prior arts using scleral ablation. However, further clinical studies are required to justified the proposed novel system with predicted advantages and efficacy based on the optical properties of sclera.
Effect of Vitamin D Supplementation on Bone Mass in Infants With 25-Hydroxyvitamin D Concentrations Less Than 50 nmol/L
Authors: Gharibeh Nathalie , Razaghi Maryam , Vanstone Catherine A. , Sotunde Olusola F. , Glenn Laura , Mullahoo Kristina , Farahnak Zahra , Khamessan Ali , Wei Shu Qin , McNally Dayre , Rauch Frank , Jones Glenville , Kaufmann Martin , Weiler Hope A. 
Published: February 2023

ImportanceThe dose of supplemental vitamin D needed in infants born with serum 25-hydroxyvitamin D (25[OH]D) concentrations less than 50 nmol/L (ie, 20 ng/mL) is unclear.ObjectiveTo determine whether a higher dose (1000 IU vs 400 IU per day) is required in infants born with 25(OH)D concentrations less than 50 nmol/L for bone mineral accretion across infancy.Design, Setting, and ParticipantsIn this prespecified secondary analysis of a double-blinded randomized clinical trial, conducted from March 2016 to March 2019 in a single center in Greater Montreal, Quebec, Canada, a consecutive sample of 139 healthy term singletons were recruited from 866 infants screened for vitamin D status at birth. Data were analyzed from June 2021 to November 2022.InterventionsCapillary blood was collected 24 to 36 hours after birth to measure serum total 25(OH)D concentrations. Infants with 25(OH)D concentrations less than 50 nmol/L were randomized to receive either 1000 IU or 400 IU per day of oral vitamin D3 supplementation from age 1 to 12 months. Infants with 25(OH)D concentrations of 50 nmol/L or greater formed a reference group.Main Outcomes and MeasuresMeasures at age 1, 3, 6, and 12 months were preplanned and included whole-body bone mineral content, lumbar spine bone mineral content, and bone mineral density using dual-energy x-ray absorptiometry, and serum 25(OH)D3 using liquid chromatography tandem mass spectrometry.ResultsOf 139 included infants, 81 (58.3%) were male, and the median (IQR) gestational age at birth was 39.6 (38.9-40.6) weeks. A total of 49 infants were included in the 1000 IU per day group, 49 infants in the 400 IU per day group, and 41 in the reference group. Mean (SD) whole-body bone mineral content was not different between trial groups over time (1000 IU per day, 173.09 [2.36] g; 400 IU per day, 165.94 [66.08] g). Similarly, no differences were observed in lumbar spine bone mineral content or density. Mean (SD) serum 25(OH)D3 concentrations were significantly higher in the 1000 IU per day group from age 3 to 12 months (3 months, 115.2 [35.3] nmol/L; 6 months, 121.6 [34.4] nmol/L; 12 months, 99.6 [28.8] nmol/L) compared with the 400 IU per day trial group (3 months, 77.4 [23.3] nmol/L; 6 months, 85.1 [18.6] nmol/L; 12 months, 82.3 [14.3] nmol/L).Conclusions and RelevanceIn this study, a higher dose of vitamin D supplementation in infants born with 25(OH)D concentrations less than 50 nmol/L did not present advantages to bone mass in infancy. This study supports a standard dose of 400 IU per day of vitamin D supplementation for breastfed infants in Montreal.Trial RegistrationClinicalTrials.gov Identifier: NCT02563015
COVID‐19 Metabolomic‐Guided Amino Acid Therapy Protects from Inflammation and Disease Sequelae
Authors: Ming Siqi , Qu Siying , Wu Yongjian , Wei Jiayou , Zhang Guoliang , Jiang Guanmin , Huang Xi 
Published: February 2023

AbstractThe outbreak of coronavirus disease 2019 (COVID‐19) has caused a worldwide pandemic since 2019. A metabolic disorder is a contributing factor to deaths from COVID‐19. However, the underlying mechanism of metabolic dysfunction in COVID‐19 patients and the potential interventions are not elucidated. Here targeted plasma metabolomic is performed, and the metabolite profiles among healthy controls, and asymptomatic, moderate, and severe COVID‐19 patients are compared. Among the altered metabolites, arachidonic acid and linolenic acid pathway metabolites are profoundly up‐regulated in COVID‐19 patients. Arginine biosynthesis, alanine, aspartate, and glutamate metabolism pathways are significantly disturbed in asymptomatic patients. In the comparison of metabolite variances among the groups, higher levels of l‐citrulline and l‐glutamine are found in asymptomatic carriers and moderate or severe patients at the remission stage. Furthermore, l‐citrulline and l‐glutamine combination therapy is demonstrated to effectively protect mice from coronavirus infection and endotoxin‐induced sepsis, and is observed to efficiently prevent the occurrence of pulmonary fibrosis and central nervous system damage. Collectively, the data reveal the metabolite profile of asymptomatic COVID‐19 patients and propose a potential strategy for COVID‐19 treatment.
Photothermal Lysis of Engineered Bacteria to Modulate Amino Acid Metabolism against Tumors
Authors: Sun Mengxue , Yang Meichen , Li Shanshan , Wang Chaohui , Zhang Fengrong , Xu Bolong , Zhang Yulian , Sun Xinxiao , Yuan Qipeng , Liu Huiyu 
Published: February 2023

AbstractBacterial‐mediated synergistic cancer therapy (BMSCT) is used as a promising tumor therapy approach. However, there are some disadvantages of bacterial therapy alone to be resolved, such as low tumor suppression rate in the treatment. In this study, a novel light‐controlled engineered bacterial material which synergistically regulates amino acid metabolism to fight tumors is developed. It transcribes l‐methionine‐γ‐lyase (MdeA) into Escherichia coli (E. coli) and loads the approved photothermal agent indocyanine green (ICG), namely E. coli‐MdeA@ICG. Using the hypoxic tropism of E. coli, genetically engineered bacteria are first loaded with photothermal agents, then selectively accumulate and replicate in the tumor region. Under laser irradiation, photothermal lysis of E. coli‐MdeA is performed to release the MdeA and consume the essential amino acid methionine (Met) in the tumor environment. In vitro cell experiments confirm that the E. coli‐MdeA + NIR group can reach 90% of the 4T1 cells killing. In 4T1 tumor‐bearing mouse models, E. coli‐MdeA@ICG shows enhanced antitumor efficacy, along with 91.8% of the tumor growth inhibited. Apoptosis of tumor cells is induced under the dual action of photothermal therapy (PTT) and amino acid metabolism therapy. This strategy provides new ideas for the combination of synthetic biology and nanotechnology in anti‐tumor.