bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting multi-vascular diseases in patients with coronary artery disease
Authors: Adiarto Suko , Nurachman Luthfian Aby , Dewangga Raditya , Indriani Suci , Taofan Taofan , Alkatiri Amir Aziz , Firman Doni , Santoso Anwar 
Published: June 2023

Background: Because of its systemic nature, the occurrence of atherosclerosis in the coronary arteries can also indicate a risk for other vascular diseases. However, screening program targeted for all patients with coronary artery disease (CAD) is highly ineffective and no studies have assessed the risk factors for developing multi-vascular diseases in general. This study constructed a predictive model and scoring system to enable targeted screening for multi-vascular diseases in CAD patients. Methods: This cross-sectional study includes patients with CAD, as diagnosed during coronary angiography or percutaneous coronary intervention from March 2021 to December 2021. Coronary artery stenosis (CAS) and abdominal aortic aneurysm (AAA) were diagnosed using Doppler ultrasound while peripheral artery disease (PAD) was diagnosed based on ABI score. Multivariate logistic regression was conducted to construct the predictive model and risk scores. Validation was conducted using ROC analysis and Hosmer-Lemeshow test. Results: Multivariate analysis showed that ages of >60 years (OR [95% CI] = 1.579 [1.153-2.164]), diabetes mellitus (OR = 1.412 [1.036-1.924]), cerebrovascular disease (OR = 3.656 [2.326-5.747]), and CAD3VD (OR = 1.960 [1.250-3.073]) increased the odds for multi-vascular disease. The model demonstrated good predictive capability (AUC = 0.659) and was well-calibrated (Hosmer-Lemeshow p = 0.379). Targeted screening for high-risk patients reduced the number needed to screen (NNS) from 6 in the general population to 3 and has a high specificity of 96.5% Conclusions: Targeted screening using clinical risk scores was able to decrease NNS with good predictive capability and high specificity
Prognostic role of C-reactive protein-to-albumin ratio in acute pancreatitis: a systematic review and meta-analysis
Authors: Mariadi I Ketut , Somayana Gde , Shalim Christina Permata , Sindhughosa Dwijo Anargha , Daniella Dian , Purwanta Made Lady Adelaida 
Published: June 2023

Background: Acute pancreatitis (AP) is a common disorder and although most of the cases are mild, the mortality risk is high when it comes to severe AP. It is therefore important to determine the severity of AP as early as possible. This review aimed to determine the prognostic value of C-reactive protein-to-albumin ratio (CRP/alb ratio) in patients with AP. Methods: We performed a systematic search on the electronic databases PubMed, Cochrane Library, and Google Scholar up to January 2023. Studies reporting CRP/alb ratio on admission and its association with severity or mortality in AP patients were included. We calculated pooled mean difference (MD) and their 95% confidence intervals (CI) using a random-effects model. Quality assessment of the included studies was appraised using a Newcastle–Ottawa scale. Results: A total of six studies comprising 2244 patients were included in this meta-analysis. Severe AP had higher CRP/alb ratio on admission than mild-moderate AP (pooled MD: 3.59; 95% CI: 2.51-4.68; p<0.00001). CRP/alb ratio was also significantly higher on non-survivor AP patients compared to survivor AP patients (pooled MD: 2.12; 95% CI: 0.43-3.8; p < 0.01). Conclusion: High CRP/alb ratio can be used as an early predictor of poor prognosis in patients with AP.
Does food biodiversity protect against malnutrition and favour the resilience to climate change-related events in Amazon Indigenous communities? A protocol for a mixed methods study
Authors: Zavaleta-Cortijo Carol , Cade Janet , Ford James , Greenwood Darren C. , Carcamo Cesar , Silvera-Ccallo Rosa , Fernandez-Neyra Connie , Lancha-Rucoba Guillermo , Pizango-Tangoa Manuel , Pizango-Inuma Rogelia , Chanchari-Huiñapi Junior , Velez-Quevedo Jorge , Inuma-Tangoa Nerita , Antazu Teresita , Miranda-Cuadros Marianella , Aparco Juan Pablo , Aro-Guardia Pedro , Verastegui Manuela , Morales-Ancajima Valeria , Bressan Tiana , Miranda J. Jaime 
Published: June 2023

Background: Undernutrition is projected to be a major consequence of climate change. Biodiversity could enhance climate change resilience by improving nutritional outcomes and providing healthy food resources during and/or after climate-related events. For Indigenous populations who currently base their diet on local biodiversity, rapid climate changes may affect their ability to produce, access or gather food and consequently impact their nutritional status. There is a knowledge gap regarding whether nutritional status among Indigenous populations is better among those who consume a diet with greater biodiversity than those who have a diet with low biodiversity. Objective: This study aims to investigate the role of food biodiversity (FBD) in nutritional resilience to extreme flooding events of Shawi Amazon Indigenous adults living in Peruvian communities that have experienced extreme floods in the past five years. Methods: This study will use a mixed-method sequential explanatory design. The quantitative component includes a cross-sectional survey to assess the association between food biodiversity (FBD) and the prevalence of anaemia in adults aged 15 to 60 years old (n=365). Anaemia will be evaluated using blood hemoglobin and serum ferritin. FBD will be measured with a food frequency questionnaire and a 24-hour dietary recall. Soil-transmitted helminth infections, malaria, and inflammatory biomarkers will also be evaluated. Qualitative component will include a community-based participatory approach to investigate the role of FBD in the responses to extreme floods. Male (n=14) and female (n=14) participants, previously identified in the quantitative phase with high and low levels of FBD, will be invited to participate in a Photovoice activity and semi-structured interviews. A analytical framework for climate change resilience will be used to integrate the data. Discussion: Findings will be integrated to identify features of diet quality to suggest nutritional interventions that are resilient to changing climatic conditions in the Amazon and respect Indigenous views.
Influence of NaCl concentration on the optical scattering properties of water-based aerosols
Authors: Pattyn Christian A. , Zenker Jake P. , Redman Brian J. , van der Laan John D. , Sanchez Andres L. , Westlake Karl , Patel Lekha , Bentz Brian Z. , Wright Jeremy B. 
Published: June 2023

We present the characterization of several atmospheric aerosol analogs
in a tabletop chamber and an analysis of how the concentration of NaCl
present in these aerosols influences their bulk optical properties.
Atmospheric aerosols (e.g., fog and haze) degrade optical signal via
light–aerosol interactions causing scattering and absorption, which
can be described by Mie theory. This attenuation is a function of the
size distribution and number concentration of droplets in the light
path. These properties are influenced by ambient conditions and the
droplet’s composition, as described by Köhler theory. It is therefore
possible to tune the wavelength-dependent bulk optical properties of
an aerosol by controlling droplet composition. We present
experimentation wherein we generated multiple microphysically and
optically distinct atmospheric aerosol analogs using salt water
solutions with varying concentrations of NaCl. The results demonstrate
that changing the NaCl concentration has a clear and predictable
impact on the microphysical and optical properties of the aerosol.
Principle and strategy of using probabilistic shaping in a flexible coherent passive optical network without optical amplifiers
Authors: Xing Sizhe , Li Guoqiang , Yan An , Shen Wangwei , Li Zhongya , Wang Jiaye , Shi Jianyang , He Zhixue , Chi Nan , Zhang Junwen 
Published: June 2023

The coherent passive optical network (CPON) has received a great deal of attention in recent years due to its superior receiver sensitivity and extended power budget for 100G and beyond. In order to fully utilize the channel capacity and achieve adaptive rate adjustment in a flexible coherent passive optical network (FLCS-CPON), constellation-shaping techniques, such as probabilistic shaping (PS), have been introduced. Unlike long-distance transmission networks, which are subject to average power constraint when optical amplifiers are utilized, commercial passive optical network systems are generally subject to peak power constraint, as no optical amplifiers are used. This difference makes the classical probabilistic-shaping (CPS) technology less efficient in CPON systems without optical amplifiers. In this study, the use cases of PS in a flexible coherent access network, including nonlinear-penalty-dominant and noise-dominated regions, are thoroughly explored. By fixing the modulation order and utilizing CPS and reversed probabilistic shaping with a fixed modulation format, a hybrid PS-based FLCS-CPON without optical amplifiers is demonstrated, achieving a peak rate of 200G and a high dynamic range boost of up to 72% from 16 to 27.5 dB in upstream burst-mode-based PS-16 quadrature amplitude modulation. Over the entire dynamic range, the net data rate varies from 168 to 85 Gbps with a power budget of 37 dB, and a dynamic range and net-rate product improvement of 55% is achieved.
Diagnostic characteristics of the 20-minute whole blood clotting test in detecting venom-induced consumptive coagulopathy following carpet viper envenoming
Authors: Tianyi Frank-Leonel , Hamza Muhammad , Abubakar Saidu B. , Al Solaiss Jaffer , Trelfa Anna , Abdullahi Hadiza L. , Iliyasu Garba , Mohammed Nuhu , Mohammed Suleman A. , Casewell Nicholas R. , Harrison Robert A. , Lalloo David G. , Stienstra Ymkje , Habib Abdulrazaq G. 
Published: June 2023

Introduction
Envenoming by Echis spp. (carpet or saw-scaled vipers) causes haemorrhage and coagulopathy and represents a significant proportion of snakebites in the savannah regions of West Africa. Early diagnosis of envenoming is crucial in the management of these patients and there is limited evidence on the utility of the 20-minute whole blood clotting test (20WBCT) in diagnosing venom-induced consumptive coagulopathy (VICC) following envenoming by Echis ocellatus.

Methods
A prospective observational cohort study was conducted at the Kaltungo General Hospital in North-eastern Nigeria from September 2019 to September 2021. Standardised 20WBCTs were conducted by trained hospital staff and citrated plasma samples were collected at numerous timepoints. Prothrombin time (PT) and international normalised ratio (INR) were determined using a semi-automated analyser and INR values were calculated using international sensitivity indices (ISI). The sensitivity, specificity, positive predictive values (PPV), negative predictive values (NPV), and likelihood ratios of the 20WBCT compared to an INR ≥ 1.4 were calculated, alongside 95% confidence intervals.

Results
We enrolled 121 patients into our study, with a median age of 26 (18.0–35.0) years and a male predominance (75.2%). The 20WBCT was positive (abnormal) in 101 out of 121 patients at timepoint 0h, of which 95 had an INR ≥ 1.4, giving a sensitivity of 87.2% (95%CI 79.4–92.8). Among patients with a negative 20WBCT (normal), six had an INR < 1.4 giving a specificity of 50% (95%CI 21.1–78.9). The positive and negative likelihood ratios were 1.7 (95%CI 1.6–1.9) and 0.3 (95%CI 0.1–0.4) respectively.

Conclusion
The 20WBCT is a simple, cheap, and easily accessible bedside test with a high sensitivity for the detection of patients with venom induced consumptive coagulopathy (VICC) following envenoming by E. ocellatus, although false positives do occur. Repeated 20WBCTs can identify patients with new, persistent, and rebound coagulopathy.
Praktik Menuju Vagina yang Sempurna: Pendisiplinan dengan Beragam Produk untuk Daerah Kewanitaan
Authors: Putri Carolina Retmawati 
Published: June 2023

AbstrakTubuh dan seksualitas perempuan selalu diatur mengikuti konstruksi yang berkembang di dalam masyarakat. Dalam hal kenikmatan seksual perempuan dituntut untuk bisa memuaskan pasangannya. Salah satu cara yang dilakukan adalah dengan memiliki penampilan yang menarik seperti yang diidealkan dalam masyarakat. Tidak hanya pada penampilan luarnya saja namun tuntutan tersebut juga berlaku untuk bagian tubuh yang paling private dari perempuan. Vagina sebagai organ yang paling intim juga mendapatkan pendisiplinan di dalam masyarakat. Penelitian ini dilakukan secara kualitatif dengan melihat praktik penggunaan produk-produk khusus untuk vagina yang dilakukan oleh para perempuan muda yang sudah memiliki aktifitas seksual yang aktif namun belum menikah. Pada akhirnya kesebelas perempuan muda sebagai informan penelitian, mencoba untuk memenuhi tuntutan yang terbentuk dalam konstruksi di masyarakat berkaitan dengan vaginanya. Cara yang mereka pilih adalah dengan memaksimalkan vaginanya menggunakan beragam produk-produk kimia khusus untuk vagina. Kata Kunci: seksualitas, vagina, pendisiplinan, dan produk kimia
Borobudur’s Changing Cultural Landscape and Genius Loci
Authors: Mladenović Katarina 
Published: June 2023

Cultural landscape is produced socially trough space and time. Cultural landscape also refers to cultural heritage that is only focused on the cultural object but also on a wider context where it is placed. This is a qualitative descriptive study which observes historical data through the conceptual framework of genius loci. Data is collected through bibliography study with the focus on how political institutions observed and built the environmental image of the place. Political institutions define how the relationship between the natural and human-made environment is sought to exist. Worldviews that have changed from the inception of Borobudur cultural landscape to the present day were influencing ongoing shifts of values, beliefs and cultural relationship towards the place.
ANALISIS PERUBAHAN KONSENTRASI TOTAL SUSPENDED SOLID SECARA MULTITEMPORAL MENGGUNAKAN CITRA SENTINEL 2A (STUDI KASUS: DANAU RAWA PENING, JAWA TENGAH)
Authors: Sasmito Bandi , Bashit Nurhadi , Rachmadiana Erliza 
Published: June 2023

AbstrakDanau Rawa Pening merupakan danau alami yang termasuk danau prioritas utama untuk dilakukan restorasi karena pertumbuhan eceng gondok yang tinggi. Pertumbuhan eceng gondok menyebabkan tertutupnya permukaan air danau dan penumpukan sedimen di dasar perairan. Sedimentasi adalah salah satu faktor penyebab munculnya Total Suspended Solid (TSS) yang menggambarkan kualitas perairan. Pemantauan perubahan kualitas perairan dapat dilakukan dengan melakukan pemetaan menggunakan metode pengindraan jauh. Pada penelitian ini pemetaan TSS dilakukan guna mencari algoritma empiris yang sesuai dengan kondisi Danau Rawa Pening dan menganalisis sebaran konsentrasi TSS melalui algoritma yang didapat. Metode yang digunakan dalam analisis konsentrasi TSS adalah pembangunan model algoritma melalui regresi data reflektan Citra Sentinel 2A tahun 2021 band 1 – 8A yang memiliki kemungkinan tinggi dalam penyerapan dan hamburan balik dari objek air dengan data TSS in situ. Percobaan penerapan regresi dipakai jika nilai ≥ 0,5 yang menunjukkan adanya hubungan keterkaitan yang kuat antara variabel TSS in situ dan nilai reflektans band. Hasil dari penelitian ini berupa 2 model dengan nilai ≥ 0,5 yaitu model persamaan regresi berganda menggunakan ratio band , nilai sebesar 0,620 dan persamaan regresinya . Sebaran konsentrasi TSS di Danau Rawa Pening memenuhi kriteria baku mutu air dengan sebagian besar berada pada kelas I dan sebagaian kecil berada kelas II, III, dan IV. Konsentrasi tertinggi menggunakan perhitungan algoritma ratio band 4/6 pada tahun 2021 sebesar 0 – 258,91 mg/L dan terendah pada tahun 2020 sebesar 0 – 6,13 mg/L.
Economic Benefits and Challenges: Funding Tertiary Education for Economic Development in Greece
Authors: Stergiou Konstantinos , Sofia Anastasiou , Filippidis Konstantinos 
Published: June 2023

It is often proposed that governments should devote resources toward tertiary education to the point where marginal social costs equal marginal social value. A critical challenge in evaluating the viability of financing higher education correlates with the difficulty of connecting educational inputs with output. The argument for investment in tertiary erudition hinges on technological advances and demographic change, whereby individuals require periodic retraining within the information age, and increasing labor productivity could reduce the effects of an aging population. The aim of the present work was to view the current system of funding tertiary education in Greece and review some evidence on the economic benefits of funding tertiary education in this Country. In spite of funding obstacles, empirical evidence indicates that graduates improve economic output and social cohesion. Prioritize funding policies for equitable access, and investigate optimal levels of taxpayer subsidy in future research. While allocative problems permeate the higher education sector within different countries, observational and empirical evidence illustrate that graduates improve economic productivity and increase the tax revenues. Overall, funding tertiary education promotes economic development in the global knowledge economy that is undergoing evolution. In addition to having direct effects on the quality of human capital, funding for postsecondary education also has indirect effects on research infrastructure, innovation and economic growth. Investments in higher education and research and development are essential for fostering economic growth, technological progress, and competitiveness.
Supporting the social inclusion of children and young adults with IDD and psychiatric comorbidities: Autobiographical narratives of practitioners and academics from Europe
Authors: Boyle Andrew , Abdulla Sam , Odrowąż-Coates Anna  , Tah Jude , Kiss Julien , Grung Rolf Magnus , Ahlström Margareta , Marsh Lynne 
Published: June 2023

The article provides a reflection on the social inclusion of children and young people with IDD and associated psychiatric comorbidity through the eyes of practitioners and academics from Norway, Scotland, Sweden, and Romania. Using an autoethnographic approach to share the first-hand experiences of supporting children and young adults with IDD from the perspective of experienced practitioners, telling their stories (individual case studies) and mapping the challenges and successes (best practice) through these professional narratives. The article also acknowledges psychiatric comorbidity in young people with IDD and how psychiatric disorders can impact social inclusion. The results of the self-reflection of active practitioners involved with complex disabilities may serve as a guide for others in sharing best practices and facing difficulties. It also shows the policy developments on a timeline of their practice. Practice-informed issues clinicians and support staff face may aid the training and share the knowledge with other experts. The value added is the interprofessional exchange created by the international contributors.
Location‐specific pathology analysis of the monopodial pulmonary vasculature in a rabbit model of bronchopulmonary dysplasia—A pilot study
Authors: Labode Jonas , Haberthür David , Hlushchuk Ruslan , Regin Yannick , Gie Andre George , Salaets Thomas , Toelen Jaan , Mühlfeld Christian 
Published: June 2023

AbstractThe mammalian pulmonary vasculature consists of functionally and morphologically heterogeneous compartments. When comparing sets of lungs, for example, in disease models or therapeutic interventions, local changes may be masked by the overall heterogeneity of the organ structure. Therefore, alterations taking place only in a sub‐compartment may not be detectable by global analysis. In the monopodial lung, the characterization of distinct vessel groups is difficult, due to the asymmetrical branching pattern. In this pilot study, a previously established method to classify segments of the monopodial pulmonary arterial tree into homogeneous groups was employed. To test its suitability for experimental settings, the method was applied to a hyperoxia (HYX, ≥95% oxygen) rabbit model of bronchopulmonary dysplasia and a normoxic control group (NOX, 21% oxygen). The method allowed the identification of morphological differences between the HYX and the NOX groups. Globally visible differences in lumen diameter were pinpointed to specific lung regions. Furthermore, local changes of wall dimension and cell layers in single compartments, that would not have been identifiable in an unfocused analysis of the whole dataset, were found. In conclusion, the described method achieves a higher precision in morphological studies of lung disease models, compared to a common, global analysis approach.
Genetic diversity of culturable fungi associated with scleractinian corals in the Gulf of Thailand
Authors: Papan Sirapong , Preedanon Sita , Saengkaewsuk Supicha , Klaysuban Anupong , Kobmoo Noppol , Pengsakun Sittiporn , Yeemin Thamasak , Suetrong Satinee , Sakayaroj Jariya 
Published: June 2023

Abstract
Coral reefs are one of the most biodiverse marine ecosystems. Diverse microbes are associated with corals, including zooxanthellae, protists, prokaryotes, and viruses. This study aimed to investigate the genetic diversity of the culturable fungi associated with scleractinian corals in the Gulf of Thailand. Ribosomal DNA sequence analysis and morphological analysis of 130 fungal isolates revealed a high diversity of fungal phylotypes from three coral species: Pavona decussata, Pocillopora damicornis and Porites lutea. Ascomycota was the most abundant fungal phylum. The predominant orders included Eurotiales, Cladosporiales, Hypocreales, Mycosphaerellales, and Diaporthales. There were eight orders of the Basidiomycota dominated by Polyporales, Hymenochaetales, Agaricales, and Wallemiales. A principal component analysis was performed to compare abundance and correlation between the fungal communities, sampling locations and coral species. The results showed that the dissimilarity of fungal communities corresponded to geographic localities. On the other hand, there was a considerable overlap between the fungal communities of different coral species. The results from this research provide information on the diversity and ecology of the fungal communities associated with scleractinian corals in the Gulf of Thailand.
The context of science fiction in the pre-service teachers’ chemistry education
Authors: Vošnjak Matej , Devetak Iztok 
Published: June 2023

Abstract
Context-based teaching and learning has a long tradition in science, especially chemistry. Audiovisual media (movies and series) can be used to provide context, and it can help overcome many students’ negative attitudes toward real science. An example of audiovisual media in which a science context can be presented is science fiction (abbreviated Sci-Fi). The purpose of this study was to investigate how the Sci-Fi context influences pre-service teachers’ attitudes and perceptions regarding the use of Sci-Fi for teaching and learning science, with a focus on chemistry, as a result of a 15-week novel elective Sci-Fi course for pre-service teachers. The main instruments used were online questionnaires, a final exam, and a rubric-based presentation evaluation form. The results of our study show that the majority of pre-service teachers consider the Sci-Fi context to be a very interesting context for science education, especially chemistry, and a useful tool for promoting students’ interest in science. Students believe that it is important to incorporate the Sci-Fi context into chemistry instruction at all levels. Our results suggest that the Sci-Fi context is useful to students as an alternative learning method that can be used to improve student learning outcomes.