bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analyzing Yemen’s health system at the governorate level amid the ongoing conflict: a case of Al Hodeida governorate
Authors: Al Waziza Raof , Sheikh Rashad , Ahmed Iman , Al-Masbhi Ghassan , Dureab Fekri 
Published: May 2023

Abstract
Background
Yemen is regarded as one of the Middle East’s poorest countries. Decades of political, economic, and social difficulties have culminated in the current protracted conflict. As a result, the globe experienced its worst humanitarian catastrophe. The ongoing war has affected several public services, notably the health sector, which is operating at less than half its capacity. This study aims to examine Yemen’s health system at the governorate level (Al Hodeida) amidst the current conflict. It analyzes current challenges and produces suggestions for enhancement.

Methods
The study used qualitative research methods such as Key Informant Interviews (KIIs) and document analysis. The study used WHO’s health systems framework to measure health system performance. Twelve KIIs were conducted via Skype with several health stakeholders. In addition, documents were analyzed to inform the subject guide, generate themes, and aid in the triangulation of results.

Results
According to the study findings, the governorate health system managed to offer a minimum level of healthcare services while making some advances in outbreak control jointly with other partners. One of the main difficulties confronting the governorate’s health system is a severe lack of financial resources forcing it to rely entirely on external aid. Furthermore, other significant deficiencies include inadequate health system organogram, low reporting capacities, insufficient funding, and scarcity of health professionals.

Conclusion
Yemen’s frail health system has been weakened by almost eight years of insecurity and conflict. If the current scenario continues, most of Yemen’s health system’s operations and indicators will likely deteriorate. On the other hand, progress in some areas, such as primary healthcare (PHC) services and disease management, is remarkable. However, for better performance, Yemen’s health system leadership and stakeholders should seek a holistic strategy to improve the entire dimensions of the health system.
Association between selenium intake and cognitive function among older adults in the US: National Health and Nutrition Examination Surveys 2011–2014
Authors: Ferdous Khondoker Adeba , Knol Linda L , Park Han-A 
Published: May 2023

Abstract
Cognitive decline occurs commonly as people age. Despite the complexity of cellular mechanisms, oxidative stress is a critical contributor to age-associated cognitive impairment. Selenium plays an important role in antioxidant defense systems. The purpose of the present study was to assess the correlation between selenium intake and cognitive function among older adults. The participants were individuals ≥65 years old (n=1681) who participated in the 2011–2014 National Health and Nutrition Examination Survey (NHANES), a country-wide cross-sectional survey. Dietary selenium intake and adequacy were evaluated with 2 d of 24-h recalls and the estimated average requirement (EAR) cut-point method, respectively. Cognitive function was assessed with the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) score, which was significantly higher when selenium intake was adequate. After adjusting for energy intake, the association was no longer significant. Inadequate intake of selenium is rare in the US and dependent on caloric intake in older adults.
Are Openly LGBTQ2+ the New Sacrificial Lambs? Campaign Contexts and the Gendered Implications for LGBTQ2+ Candidates
Authors: Everitt Joanna , Tremblay Manon 
Published: May 2023

AbstractRecent increases in the number of openly LGBTQ2+ candidates have not resulted in a corresponding rise in the number of LGBTQ2+ politicians elected to the Canadian House of Commons, reviving the hypothesis of the “sacrificial lamb” candidacies. Drawing upon Lovenduski and Norris’ work on political recruitment, we analyze the backgrounds and experiences of the 172 LGBTQ2+ candidates who ran in the 2015, 2019 and 2021 federal elections in Canada. Our approach is based on the idea that LGBTQ2+ candidacies are the new sacrificial lambs of Canadian politics, although some of them seem less likely to be sacrificed than others. Indeed, we highlight how the electoral opportunities (for example, district competitiveness) afforded to LGBTQ2+ cis men are more likely to result in success than those afforded to LGBTQ2+ cis women or gender minority candidates.
A meta-analysis of cognitive interventions for patients with recent onset psychosis: are they effective for improving functioning?
Authors: Petkari Eleni , Martín-María Natalia , Sánchez-Gutiérrez Teresa , Fernández-Castilla Belén , Calvo Ana 
Published: May 2023

AbstractThe increasing popularity of cognitive interventions for patients with psychosis calls for further exploration on how these interventions may benefit functional outcomes. We conducted a meta-analysis of randomized controlled trials (RCTs) to examine the effectiveness of cognitive interventions (i.e. Cognitive Remediation, Cognitive Training, Social Cognition, and their combination) on functioning of patients with recent onset psychosis, established as the period within the first five years from the first episode. The following databases were searched: Proquest, PUBMED/MEDLINE, PsycINFO, WOS, Scopus for research published until January 2022. In total, 12 studies were eligible. The total number of participants was 759, of which 32.2% in the intervention and 30.8% in the control group were female. We extracted data to calculate the standardized mean change from pre-test to post-test comparing the intervention with the control conditions. Overall, there was no effect of any of the cognitive intervention types on functioning. None of the examined factors (intervention type, length, and modality; control condition, follow-up time; cognitive functions; medication; symptoms) seemed to moderate these findings. Our results indicate that cognitive interventions as standalone interventions do not appear to improve functioning in patients with recent onset psychosis. Given the small number of eligible studies, further RCTs with larger and more refined samples are needed to test whether these interventions should be applied as single interventions with these patients.
A systematic review of digital interventions for smoking cessation in patients with serious mental illness
Authors: Martinez Agulleiro Luis , Patil Bhagyashree , Firth Joseph , Sawyer Chelsea , Amann Benedikt L. , Fonseca Francina , Torrens Marta , Perez Victor , Castellanos Francisco Xavier , Kane John M. , Guinart Daniel 
Published: May 2023

AbstractTobacco smoking is highly prevalent among patients with serious mental illness (SMI), with known deleterious consequences. Smoking cessation is therefore a prioritary public health challenge in SMI. In recent years, several smoking cessation digital interventions have been developed for non-clinical populations. However, their impact in patients with SMI remains uncertain. We conducted a systematic review to describe and evaluate effectiveness, acceptability, adherence, usability and safety of digital interventions for smoking cessation in patients with SMI. PubMed/MEDLINE, EMBASE, CINAHL, Web of Science, PsychINFO and the Cochrane Tobacco Addiction Group Specialized Register were searched. Studies matching inclusion criteria were included and their information systematically extracted by independent investigators. Thirteen articles were included, which reported data on nine different digital interventions. Intervention theoretical approaches ranged from mobile contingency management to mindfulness. Outcome measures varied widely between studies. The highest abstinence rates were found for mSMART MIND (7-day point-prevalent abstinence: 16–40%). Let's Talk About Quitting Smoking reported greater acceptability ratings, although this was not evaluated with standardized measures. Regarding usability, Learn to Quit showed the highest System Usability Scale scores [mean (s.d.) 85.2 (15.5)]. Adverse events were rare and not systematically reported. Overall, the quality of the studies was fair to good. Digitally delivered health interventions for smoking cessation show promise for improving outcomes for patients with SMI, but lack of availability remains a concern. Larger trials with harmonized assessment measures are needed to generate more definitive evidence and specific recommendations.
Enacting citizenship through writing: an analysis of a diary written by a man with Alzheimer's disease
Authors: Lotherington Ann Therese , Obstfelder Aud Uhlen 
Published: May 2023

AbstractCitizenship and dementia studies have, during the last 15 years, grown into a substantial body of research recognising the experiences and agentic powers of people living with dementia. This article aims to contribute to and extend this research field. We undertake the aim through a feminist posthumanist non-representational analysis of a diary written by a man with Alzheimer's disease to explore the diary's potential to enact citizenship. The first section of the article examines current approaches to democracy, citizenship and dementia, and advances the concept intra-active citizenship, an approach that extends the individual and understands citizenship as enacted in and through entanglements of human–more-than-human agents. The second section is a theory-informed analysis of the diary, in which events, relations, doings and affective resonances constitute the analytical categories. The third section discusses whether the diary and the writing of it might enact citizenship, and if so, what kind of citizenship. The article concludes with a reflection on how our posthumanist, non-representational approach might pave a new path for theorising and, hence, contribute to new understandings of dementia and citizenship.
Trends in retirement and retirement income choices by TIAA participants: 2000–2018
Authors: Brown Jeffrey R. , Poterba James M. , Richardson David P. 
Published: May 2023

AbstractThis paper documents trends over the last two decades in retirement behavior and retirement income choices of participants in TIAA, a large and mature defined contribution plan. From 2000 and 2018, the average age at which TIAA participants stopped contributing to their accounts, which is a lower bound on their retirement age, rose by 1.2 years for female and 2.0 years for male participants. There is considerable variation in the elapsed time between the time of the last contribution to and the first income draw from plan accounts. Only 40% of participants take an initial income payment within 48 months of their last contribution. Later retirement and lags between retirement and the first retirement income payout led to a growing fraction of participants reaching the required minimum distribution (RMD) age before starting income draws. Between 2000 and 2018, the fraction of first-time income recipients who took no income until their RMD rose from 10% to 52%, while the fraction of these recipients who selected a life-contingent annuitized payout stream declined from 61% to 18%. Among those who began receiving income before age 70, annuitization rates were significantly higher than among those who did so at older ages. Aggregating across all income-receiving beneficiaries at TIAA, not just new income recipients, the proportion with a life annuity as part of their payout strategy fell from 52% in 2008 to 31% in 2018. By comparison, the proportion of all income recipients taking an RMD payment rose from 16% to 29%. About one-fifth of retirees received more than one type of income; the most common pairing was an RMD and a life annuity. In the later years of our sample, the RMD was becoming the de facto default distribution option for newly retired TIAA participants.
Will the centre hold? Countering the erosion of the principle of distinction on the digital battlefield
Authors: Mačák Kubo 
Published: May 2023

AbstractThis article argues that the growing involvement of civilians in activities on the digital battlefield during armed conflicts puts individuals at risk of harm and contributes to the erosion of the principle of distinction, a cornerstone of international humanitarian law (IHL). The article begins by outlining the ongoing trend of civilianization of the digital battlefield and puts forward brief scenarios to illustrate it. It then examines the narrow circumstances under which such forms of civilian involvement may qualify as direct participation in hostilities under IHL, and discusses what this means for the individuals concerned, particularly from the perspective of their loss of protection under the law. The analysis shows that certain types of State conduct which put civilians in harm's way by inducing them to directly participate in hostilities may constitute standalone violations of IHL and human rights law obligations. Beyond these specific prescriptions, the encouragement of civilian involvement undermines the principle of distinction, with dangerous ripple effects on the interpretation of those rules of IHL that flow from it. Accordingly, the article concludes that States should act to reverse the trend of civilianization of the digital battlefield and refrain as much as possible from involving civilians in the conduct of cyber hostilities.
Maternal incarceration increases the risk of self-harm but not suicide: a matched cohort study
Authors: Cumming Craig , Bell Megan F. , Segal Leonie , Spittal Matthew J. , Kinner Stuart A. , Dennison Susan , Dawe Sharon , Preen David B. 
Published: May 2023

Abstract

Aims
Children of incarcerated mothers are at increased risk of experiencing multiple adversity such as poverty, mental illness and contact with child protection services (CPS), including being taken into out of home care (OOHC). However, little is known about whether these children are at increased risk of suicide or self-harm compared to children not exposed to maternal incarceration or about the factors that may contribute to this. We aimed to investigate differences in the risk of suicide and self-harm between children exposed to maternal incarceration and those not exposed and examine how socio-demographic factors, maternal mental illness and CPS contact (with or without OOHC) may affect these outcomes.

Methods
We used a retrospective matched cohort study design, comparing 7674 children exposed to maternal incarceration with 7674 non-exposed children. We used multivariable Cox proportional hazards regression to compare the risk of suicide and self-harm between exposed and non-exposed groups, controlling for geographical remoteness, CPS contact and maternal mental illness.

Results
There was no significant difference in the rate of suicide (rate ratio [RR] = 1.49; 95% confidence interval [CI]: 0.78, 2.87) or risk of suicide (adjusted hazard ratio [aHR] = 0.92; 95% CI: 0.43, 1.96) between the two groups. However, the exposed group had a significantly higher rate of self-harm (RR = 2.83; 95% CI: 2.50, 3.21) and a significantly higher risk of self-harm (aHR = 1.74; 95% CI: 1.45, 2.09) compared to those non-exposed. CPS contact with or without OOHC was independently associated with an increased risk of self-harm for both groups.

Conclusion
Children exposed to maternal incarceration are at an increased risk of self-harm and should be prioritized to receive targeted, multimodal support that continues after the mother’s release from prison. The association between CPS contact and self-harm warrants further research.
Wie fair testet der WÜRT 1 die Rechtschreibleistungen von mehrsprachigen Kindern?
Authors: Brandenburg Janin , Huschka Sina S. , Visser Linda , Cartschau Friederike , Goldammer und Ariane von 
Published: May 2023

Zusammenfassung: Bei der Diskussion über Bildungsgerechtigkeit für mehrsprachige Kinder steht u. a. die Testfairness standardisierter Schulleistungstests im Fokus. So sollte eine Leistungsdiagnostik dieser Kinder auf Tests zurückgreifen, deren Fairness für Kinder mit nicht-deutscher Muttersprache empirisch abgesichert ist, denn nur so lassen sich die Testergebnisse in gleicher Weise interpretieren wie bei Kindern, die einsprachig deutsch aufwachsen. Ein Ziel bestand daher darin, die Testfairness des Würzburger Rechtschreibtests für 1. und 2. Klassen (WÜRT 1 – 2) zu überprüfen. Außerdem wurde analysiert, ob mehrsprachige Kinder die gleichen Fehlerschwerpunkte in der Rechtschreibung aufweisen wie einsprachige Kinder. Es nahmen 146 einsprachige und 107 mehrsprachige Kinder am Ende der ersten Klasse teil. Analysen zum Differential Item Functioning zeigten nur bei einem der insgesamt 36 Items Hinweise auf eine systematische Benachteiligung mehrsprachiger Kinder. Mit dem WÜRT 1 liegt somit ein faires Testverfahren vor, dessen Einsatz auch bei mehrsprachigen Kindern empfohlen werden kann. Die ein- und die mehrsprachigen Kinder unterschieden sich in der Fehleranzahl, nicht aber ihren qualitativen Fehlerprofilen. Dies legt nahe, dass eine Rechtschreibförderung für mehrsprachige Kinder an den gleichen Schwerpunkten ansetzen kann wie bei einsprachigen Kindern.
Emissions Background, Climate, and Season Determine the Impacts of Past and Future Pandemic Lockdowns on Atmospheric Composition and Climate
Authors: Hickman Jonathan E. , Bauer Susanne E. , Faluvegi Gregory S. , Tsigaridis Kostas 
Published: May 2023

AbstractCOVID‐19 pandemic responses affected atmospheric composition and climate. These effects depend on the background emissions, climate, and season in which they occur. Although using multiple scenarios is common in explorations of long‐term climate change, they are rarely used to explore atmospheric composition or climate changes in response to transient emission perturbations on the scale of COVID‐19 lockdowns. We used the ModelE Earth system model to evaluate how atmospheric and climate impacts depend on the decade and season in which lockdowns occurred. Global COVID‐19‐related anomalies in aerosols and trace gases differed by up to an order of magnitude or more when comparing lockdowns in 1980, 2008, 2020, and 2051. Regional atmospheric composition anomalies tended to be largest when emissions were near a historical peak: 1980 in Europe and temperate North America, 2008 or 2020 in eastern Asia, and 2051 in south Asia. Regional aerosol direct effect anomalies were almost always less than 0.1 W m−2 during the first pandemic year, but over 0.1 W m−2 in Europe and exceeded 0.2 W m−2 in Europe and temperate North America in 1980, generally changing in tandem with regional emissions. In contrast, direct effect anomalies in Asia were positive in 1980 and negative in 2008, suggesting they may be primarily determined by exogenous emission anomalies. Shifting COVID‐19 onset in 2020 by 3, 6, or 9 months also altered atmospheric composition on the order of 2%–25% globally. In all scenarios, changes in surface temperature or precipitation appeared unrelated to local atmospheric compositional changes.
Wind and Turbulence Observations With the Mars Microphone on Perseverance
Authors: Stott Alexander E. , Murdoch Naomi , Gillier Martin , Banfield Don , Bertrand Tanguy , Chide Baptiste , De la Torre Juarez Manuel , Hueso Ricardo , Lorenz Ralph , Martinez German , Munguira Asier , Mora Sotomayor Luis , Navarro Sara , Newman Claire , Pilleri Paolo , Pla‐Garcia Jorge , Rodriguez‐Manfredi Jose Antonio , Sanchez‐Lavega Agustin , Smith Michael , Viudez Moreiras Daniel , Williams Nathan , Maurice Sylvestre , Wiens Roger C. , Mimoun David 
Published: May 2023

AbstractWe utilize SuperCam's Mars microphone to provide information on wind speed and turbulence at high frequencies on Mars. To do so, we first demonstrate the sensitivity of the microphone signal level to wind speed, yielding a power law dependence. We then show the relationship between the microphone signal level and pressure, air and ground temperatures. A calibration function is constructed using Gaussian process regression (a machine learning technique) taking the microphone signal and air temperature as inputs to produce an estimate of the wind speed. This provides a high rate wind speed estimate on Mars, with a sample every 0.01 s. As a result, we determine the fast fluctuations of the wind at Jezero crater which highlights the nature of wind gusts over the Martian day. To analyze the turbulent behavior of this wind speed estimate, we calculate its normalized standard deviation, known as gustiness. To characterize the behavior of this high frequency turbulent intensity at Jezero crater, correlations are shown between the evaluated gustiness statistic and pressure drop rates/sizes, temperature and energy fluxes. This has implications for future atmospheric models on Mars, taking into account turbulence at the finest scales.
Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration
Authors: Marinkovic Milos , Tran Olivia N. , Wang Hanzhou , Abdul-Azees Parveez , Dean David D. , Chen Xiao-Dong , Yeh Chih-Ko 
Published: May 2023

AbstractSalivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical manifestation that has the potential to cause severe oral and/or systemic diseases and compromise quality of life. Currently, the standard-of-care for this condition remains palliative. A variety of approaches have been employed to restore saliva production, but they have largely failed due to damage to both secretory cells and the extracellular matrix (niche). Transplantation of allogeneic cells from healthy donors has been suggested as a potential solution, but no definitive population of SG stem cells, capable of regenerating the gland, has been identified. Alternatively, mesenchymal stem cells (MSCs) are abundant, well characterized, and during SG development/homeostasis engage in signaling crosstalk with the SG epithelium. Further, the trans-differentiation potential of these cells and their ability to regenerate SG tissues have been demonstrated. However, recent findings suggest that the “immuno-privileged” status of allogeneic adult MSCs may not reflect their status post-transplantation. In contrast, autologous MSCs can be recovered from healthy tissues and do not present a challenge to the recipient’s immune system. With recent advances in our ability to expand MSCs in vitro on tissue-specific matrices, autologous MSCs may offer a new therapeutic paradigm for restoration of SG function.
Genetic architecture of brain age and its causal relations with brain and mental disorders
Authors: Leonardsen Esten H. , Vidal-Piñeiro Didac , Roe James M. , Frei Oleksandr , Shadrin Alexey A. , Iakunchykova Olena , de Lange Ann-Marie G. , Kaufmann Tobias , Taschler Bernd , Smith Stephen M. , Andreassen Ole A. , Wolfers Thomas , Westlye Lars T. , Wang Yunpeng 
Published: May 2023

AbstractThe difference between chronological age and the apparent age of the brain estimated from brain imaging data—the brain age gap (BAG)—is widely considered a general indicator of brain health. Converging evidence supports that BAG is sensitive to an array of genetic and nongenetic traits and diseases, yet few studies have examined the genetic architecture and its corresponding causal relationships with common brain disorders. Here, we estimate BAG using state-of-the-art neural networks trained on brain scans from 53,542 individuals (age range 3–95 years). A genome-wide association analysis across 28,104 individuals (40–84 years) from the UK Biobank revealed eight independent genomic regions significantly associated with BAG (p < 5 × 10−8) implicating neurological, metabolic, and immunological pathways – among which seven are novel. No significant genetic correlations or causal relationships with BAG were found for Parkinson’s disease, major depressive disorder, or schizophrenia, but two-sample Mendelian randomization indicated a causal influence of AD (p = 7.9 × 10−4) and bipolar disorder (p = 1.35 × 10−2) on BAG. These results emphasize the polygenic architecture of brain age and provide insights into the causal relationship between selected neurological and neuropsychiatric disorders and BAG.