bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of chopper-stabilized ASIC preamplifier for improving noise equivalent magnetic induction of search coil magnetometer probing space plasma waves
Authors: Ozaki Mitsunori , Tokunaga Yuya , Koji Hiroki , Yagitani Satoshi 
Published: May 2023

AbstractSpace-based search coil (SC) magnetometers connected to preamplifiers have been used to investigate magnetic field vectors of plasma waves from 100 mHz to 10 kHz for understanding magnetospheric dynamics. However, flicker noise below several 100 Hz of typical preamplifiers degrades the noise equivalent magnetic induction (NEMI) of SCs and affects the probing of plasma waves from 100 mHz to 100 Hz. In this study, we developed a chopper-stabilized preamplifier using application-specific integrated circuit (ASIC) technology for improving the NEMI below 100 Hz while maintaining miniaturization and a low power consumption. The chopper ASIC preamplifier fits into a layout size of 2.3 × 3.4 mm in a bare chip. We used two SC sensors with different (20 cm and 5 cm) lengths to evaluate the NEMI with the prototype of the chopper ASIC preamplifier. At 100 mHz, the NEMI values of the 20-cm length and 5-cm length SCs were 0.1 nT/Hz1/2 and 1.9 nT/Hz1/2, respectively, which can detect typical electromagnetic ion cyclotron waves in the magnetosphere. The NEMI value at 100 mHz for the 5-cm-length SC was improved by approximately 19 dB compared with that for a previous ASIC preamplifier without chopping. We conducted temperature tests for the chopper ASIC preamplifier to evaluate the behavior for under a wide temperature range from − 40 to + 100 °C. The temperature coefficient of the gain was approximately − 0.02 dB/°C, which is a sufficiently low temperature-dependence. The use of ASIC technology achieved high stability under the wide temperature range and radiation tolerance. Thus, the chopper ASIC preamplifier with high robustness and ultra-low noise characteristics is suitable for plasma wave observations in harsh space environments for future missions.
Graphical Abstract
Development of a high-performance seismic phase picker using deep learning in the Hakone volcanic area
Authors: Kim Ahyi , Nakamura Yuji , Yukutake Yohei , Uematsu Hiroki , Abe Yuki 
Published: May 2023

AbstractIn volcanic regions, active earthquake swarms often occur in association with volcanic activity, and their rapid detection and analysis are crucial for volcano disaster prevention. Currently, these processes are ultimately left to human judgment and require significant time and money, making detailed real-time verification impossible. To overcome this issue, we attempted to apply machine learning, which has been successfully applied to various seismological fields to date. For seismic phase pick, several models have already been trained using a large amount of training data (mainly crustal earthquakes). Although there are some cases in which these models can be applied without any problems, regional dependence on pre-trained models has been reported. Since this study targets earthquakes in a volcanic region, applying existing pre-trained models may be difficult. Therefore, in this study, we compared three models; the publicly available trained model (model 0), a model which was trained with approximately 220,000 P- and S-wave onset reading data recorded at the Hakone volcano from 1999 to 2020 with initialized parameters (model 1) using the same architecture, and a model fine-tuned with the aforementioned Hakone data using the parameters of model 0 as initial values (model 2), and evaluated their phase identification performance for the Hakone data. As a result, the seismic phase detection rates of models 1 and 2 were much higher than those of model 0. However, small-amplitude signals are often missed when multiple seismic events occur within a detection time window. Therefore, we created training data with two earthquakes in the same time window, retrained the model using the data, and successfully detected events that previously would have been missed. In addition, it was found that more events were detected by setting the threshold to a low probability value for detection, increasing the number of seismic phase detections, and filtering by phase association and hypocenter location.
Graphical Abstract
Fidelity to the ACT SMART Toolkit: an instrumental case study of implementation strategy fidelity
Authors: Tschida Jessica E. , Drahota Amy 
Published: May 2023

Abstract
Background
Evidence-based practices (EBPs) are shown to improve a variety of outcomes for autistic children. However, EBPs often are mis-implemented or not implemented in community-based settings where many autistic children receive usual care services. A blended implementation process and capacity-building implementation strategy, developed to facilitate the adoption and implementation of EBPs for autism spectrum disorder (ASD) in community-based settings, is the Autism Community Toolkit: Systems to Measure and Adopt Research-based Treatments (ACT SMART Toolkit). Based on an adapted Exploration, Adoption decision, Preparation, Implementation, Sustainment (EPIS) Framework, the multi-phased ACT SMART Toolkit is comprised of (a) implementation facilitation, (b) agency-based implementation teams, and (c) a web-based interface. In this instrumental case study, we developed and utilized a method to evaluate fidelity to the ACT SMART Toolkit. This study responds to the need for implementation strategy fidelity evaluation methods and may provide evidence supporting the use of the ACT SMART Toolkit.

Methods
We used an instrumental case study approach to assess fidelity to the ACT SMART Toolkit during its pilot study with six ASD community agencies located in southern California. We assessed adherence, dose, and implementation team responsiveness for each phase and activity of the toolkit at both an aggregate and individual agency level.

Results
Overall, we found that adherence, dose, and implementation team responsiveness to the ACT SMART Toolkit were high, with some variability by EPIS phase and specific activity as well as by ASD community agency. At the aggregate level, adherence and dose were rated notably lowest during the preparation phase of the toolkit, which is a more activity-intensive phase of the toolkit.

Conclusions
This evaluation of fidelity to the ACT SMART Toolkit, utilizing an instrumental case study design, demonstrated the potential for the strategy to be used with fidelity in ASD community-based agencies. Findings related to the variability of implementation strategy fidelity in the present study may also inform future adaptations to the toolkit and point to broader trends of how implementation strategy fidelity may vary by content and context.
Sleep Fragmentation, Electroencephalographic Slowing, and Circadian Disarray in a Mouse Model for Intensive Care Unit Delirium
Authors: Dulko Elzbieta , Jedrusiak Michal , Osuru Hari P. , Atluri Navya , Illendula Meghana , Davis Eric M. , Beenhakker Mark P. , Lunardi Nadia 
Published: May 2023

BACKGROUND:
We aimed to further validate our previously published animal model for delirium by testing the hypothesis that in aged mice, Anesthesia, Surgery and simulated ICU conditions (ASI) induce sleep fragmentation, electroencephalographic (EEG) slowing, and circadian disarray consistent with intensive care unit (ICU) patients with delirium.

METHODS:
A total of 41 mice were used. Mice were implanted with EEG electrodes and randomized to ASI or control groups. ASI mice received laparotomy, anesthesia, and simulated ICU conditions. Controls did not receive ASI. Sleep was recorded at the end of ICU conditions, and hippocampal tissue was collected on EEG recording. Arousals, EEG dynamics, and circadian gene expression were compared with t tests. Two-way repeated measures analysis of variance (RM ANOVA) was used to assess sleep according to light.

RESULTS:
ASI mice experienced frequent arousals (36.6 ± 3.2 vs 26.5 ± 3.4; P = .044; 95% confidence interval [CI], 0.29–19.79; difference in mean ± SEM, 10.04 ± 4.62) and EEG slowing (frontal theta ratio, 0.223 ± 0.010 vs 0.272 ± 0.019; P = .026; 95% CI, −0.091 to −0.007; difference in mean ± SEM, −0.05 ± 0.02) relative to controls. In ASI mice with low theta ratio, EEG slowing was associated with a higher percentage of quiet wakefulness (38.2 ± 3.6 vs 13.4 ± 3.8; P = .0002; 95% CI, −35.87 to −13.84; difference in mean ± SEM, −24.86 ± 5.19). ASI mice slept longer during the dark phases of the circadian cycle (nonrapid eye movement [NREM], dark phase 1 [D1]: 138.9 ± 8.1 minutes vs 79.6 ± 9.6 minutes, P = .0003, 95% CI, −95.87 to −22.69, predicted mean difference ± SE: −59.28 ± 13.89; NREM, dark phase 2 (D2): 159.3 ± 7.3 minutes vs 112.6 ± 15.5 minutes, P = .006, 95% CI, −83.25 to −10.07, mean difference ± SE, −46.66 ± 13.89; rapid eye movement (REM), D1: 20.5 ± 2.1 minutes vs 5.8 ± 0.8 minutes, P = .001, 95% CI, −24.60 to −4.71, mean difference ± SE, −14. 65 ± 3.77; REM, D2: 21.0 ± 2.2 minutes vs 10.3 ± 1.4 minutes, P = .029, 95% CI, −20.64 to −0.76, mean difference ± SE, −10.70 ± 3.77). The expression of essential circadian genes was also lower in ASI mice (basic helix-loop-helix ARNT like [BMAL1]: −1.3 fold change; circadian locomotor output cycles protein kaput [CLOCK]: −1.2).

CONCLUSIONS:
ASI mice experienced EEG and circadian changes mimicking those of delirious ICU patients. These findings support further exploration of this mouse approach to characterize the neurobiology of delirium.
Clinical Utility of the Cardiorespiratory Optimal Point in Patients with Heart Failure
Authors: KROESEN SOPHIE H. , BAKKER ESMÉE A. , SNOEK JOHAN A. , VAN KIMMENADE ROLAND R. J. , MOLINGER JEROEN , ARAÚJO CLAUDIO G. , HOPMAN MARIA T. E. , EIJSVOGELS THIJS M. H. 
Published: May 2023

ABSTRACT

Introduction
We assessed the cardiorespiratory optimal point (COP)—the minimal V̇
E/V̇O2 in a given minute of an incremental cardiopulmonary exercise test—in patients with heart failure (HF) and aimed to determine 1) its association with patient and disease characteristics, 2) changes after an exercise-based cardiac rehabilitation program (CR), and 3) the association with clinical outcomes.

Methods
We studied 277 HF patients (67 (58–74) yr, 30% female, 72% HF with restricted ejection fraction) between 2009 and 2018. Patients participated in a 12- to 24-wk CR program, and COP was assessed pre- and post-CR. Patient and disease characteristics and clinical outcomes (mortality and cardiovascular-related hospitalization) were extracted from patient files. The incidence of clinical outcomes was compared across COP tertiles (low, <26.0; moderate, 26.0–30.7; high, >30.7).

Results
Median COP was 28.2 (24.9–32.1) and was reached at 51% ± 15% of V̇O2peak. Lower age, female sex, higher body mass index, the absence of a pacemaker or the absence of chronic obstructive pulmonary disease, and lower N-terminal prohormone brain natriuretic peptide concentrations were associated with a lower COP. Participation in CR reduced COP (−0.8; 95% confidence interval, −1.3 to −0.3). Low COP had a reduced risk (adjusted hazard ratio, 0.53; 95% confidence interval, 0.33–0.84) for adverse clinical outcomes as compared with high COP.

Conclusions
Classic cardiovascular risk factors are associated with a higher, more unfavorable, COP. CR-based exercise training reduces COP, whereas a lower COP is associated with a better clinical prognosis. As COP can be established during a submaximal exercise test, this may offer novel risk stratification possibilities for HF care programs.
Survival impact of fibrotic interstitial lung abnormalities in resected stage IA non-small cell lung cancer
Authors: Jeong Won Gi , Kim Yun-Hyeon 
Published: May 2023

Objectives: To assess the association between fibrotic interstitial lung abnormalities (ILAs) and long-term survival in patients with resected Stage IA non-small cell lung cancer (NSCLC). Methods: Data of patients who underwent curative resection of pathological Stage IA NSCLC between 2010 and 2015 were retrospectively analysed. ILAs were evaluated using pre-operative high-resolution CT scans. The association between ILAs and cause-specific mortality was assessed via Kaplan–Meier analysis and the log-rank test. Cox proportional hazards regression was performed to determine the risk factors for cause-specific death. Results: Overall, 228 patients were identified (63.27 ± 8.54 years, 133 men [58.3%]). ILAs were detected in 24 patients (10.53%). Fibrotic ILAs were observed in 16 patients (7.02%), and there was a significantly higher cause-specific mortality rate among patients with fibrotic ILAs compared with patients with no ILAs (p < 0.001). Patients with fibrotic ILAs had a significantly higher cause-specific mortality rate than patients without ILAs at 5 post-operative years (survival rate: 61.88% vs 93.03%, p < 0.001). The presence of afibrotic ILA was an independent risk factor for cause-specific death (adjusted hazard ratio = 3.22; 95% confidence interval: 1.10, 9.44; p = 0.033). Conclusion: The presence of afibrotic ILA was a risk factor for cause-specific death in patients with resected Stage IA NSCLC. Radiologists and clinicians should be familiar with the relatively new concept of ILAs and understand the close association between ILA status and long-term survival in resected Stage IA NSCLC. Patients presenting fibrotic ILAs should receive appropriate surveillance and management to optimise prognosis. Advances in knowledge: Fibrotic ILAs are important findings implicated inthe long-term survival of patients with resected Stage IA NSCLC. Specific management is required for this group.
Performance of panoramic radiography compared with computed tomography in the evaluation of pathological changes in the maxillary sinuses: a systematic review and meta-analysis
Authors: Fischborn Amanda Regina , Andreis Jéssica Daniela , Wambier Leticia Maíra , Pedroso Caique Mariano , Claudino Marcela , Franco Gilson Cesar Nobre 
Published: May 2023

Objective: A systematic review was performed to evaluate the performance of panoramic radiography (PR) vs CT or cone beam CT (CBCT) in the diagnosis of pathological maxillary sinuses. Methods: This review was registered in the PROSPERO database under the number CRD42020211766. Observational studies that compared PR with CT/CBCT were used to evaluate pathological changes in the maxillary sinuses. A complete search of seven primary databases and gray literature was carried out. The risk of bias was assessed according to the Newcastle-Ottawa tool, and the GRADE tool was used to assess the quality of evidence. A binary meta-analysis was performed to assess the effectiveness of evaluating pathological alterations in the maxillary sinuses in PR and CT/CBCT. Results: Seven studies were included in our study, out of which four were included in a quantitative analysis. All studies were classified as low risk of bias. Five studies compared PR with CBCT and two studies compared PR to CT. The most common pathological alteration in maxillary sinuses reported was mucosal thickening. CT/CBCT was seen to be the most effective method for assessing pathological changes in the maxillary sinus when compared to PR (RR = 0.19, 95% confidence interval [CI] = 0.05 to 0.70, p = 0.01). Conclusion: CT/CBCT are the most appropriate imaging methods to evaluate pathological changes in the maxillary sinuses, while PR is still limited in the evaluation of these changes being considered only for initial diagnosis.
Post-Cardiac arrest targeted temperature management in a parturient with severe COVID-19 disease
Authors: Eman Ali , Balaban Onur , Özmen Süner Kezban , Özgün Bora 
Published: May 2023

Background and Objective: Targeted temperature management (TTM) may improve neurological outcomes and mortality after cardiac arrest. We present a targeted mild hypothermia treatment in a postpartum patient with COVID-19 after successful cardiopulmonary resuscitation (CPR).
Case presentation: A 23 year old, 26-week pregnant patient with the diagnosis of COVID-19. The patient developed respiratory arrest followed by cardiac arrest and underwent CPR for six minutes. The patient underwent an emergency cesarean section after CPR in intensive care unit. After the resuscitation, 72-hours hypothermia protocol was initiated. We extubated the patient 13 days after the hypothermia procedure. The patient was conscious and cooperative. Respiratory distress worsened in the following days; the patient was re-intubated 18 days after the TTM. The benefit of targeted hypothermia was improved neurologic outcome in our patient. However, severe infectious complications led to multi-organ failure and the patient died on the 45th ICU admission day.
doi: https://doi.org/10.12669/pjms.39.4.7193
How to cite this: Eman A, Balaban O, Süner KÖ, Özgün B. Post-Cardiac arrest targeted temperature management in a parturient with severe COVID-19 disease. Pak J Med Sci. 2023;39(4):---------. doi: https://doi.org/10.12669/pjms.39.4.7193
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Professional burnout syndrome in a group of nursing staff employed in a psychiatric hospital
Authors: Tomaszewska Katarzyna , Porczak Waldemar , Guty Edyta , Majchrowicz Bożena 
Published: May 2023

Nurses are one of the occupational groups most exposed to stress in the health care system. In their daily work, the staff of a psychiatric ward often encounters threats, aggression or unpredictability of patients' behavior. Employees, including nurses, often feel discomfort related to the treatment of patients admitted against their will, the need to use direct coercion. In psychiatry, it is also burdensome to participate in family matters of patients, to solve their problems. The group of factors recognized as stressful and causing psychological burden for nurses includes a large number of patients under their care, their serious condition as well as physical and verbal aggression of the patient and violence.
The aim of the study was to present the problem of occupational burnout in a group of nursing staff employed in a psychiatric hospital
Material and methods 203 nurses participated in the study. The research tool was a proprietary questionnaire and a standardized tool, the Ch. Maslach. The level of statistical significance in this study was p<0.05.
Results The average occupational burnout rate was 34.9% ± 20.9%. Emotional exhaustion was assessed at 32.5% ± 28.5%, the level of depersonalization at 23.1% ± 26.1%. The main motivators in the work of nurses are earnings (57.3%), willingness to help others (54.4%) and a good atmosphere at work (35%).
Conclusions: Mental burden in the work of a psychiatric nurse results in the development of occupational stress leading to occupational burnout. Actions are recommended to counteract the professional burnout syndrome
use of adrenaline in cardiac arrest - impact on survival to discharge from the hospital
Authors: Zimnicki Patryk , Lato Marta , Iberszer Konrad , Litwiniuk Maria , Zaniuk Marcin , Hurkała Kamil , Antonik Dominika , Denys Barbara , Góra Karolina , Zdziennicki Wojciech 
Published: May 2023

Introduction and objective: Epinephrine is the most important and primary drug that resuscitation team use to reverse cardiac arrest. The provision of epinephrine is currently suggested by both the American Heart Association and the European Resuscitation Council. It is vital to improving the return of spontaneous circulation (ROSC), however the evidence for the use of adrenaline in resuscitation is inconclusive.
Materials and methods: The literature was reviewed in the Pubmed database, in the Via Medica Journals database, and in the guidelines of the Polish Society of Anesthesiology, European Resuscitation Council and the American Heart Association with the use of keywords.
State of knowledge: There is a clear evidence of an association between epinephrine and increased return of spontaneous circulation (ROSC). Its action is based on stimulation of alpha- and beta-adrenergic receptors. Epinephrine have a role in resuscitation, during CPR it increases the probability of restoring cardiac activity with pulses, which is intermediate step toward long-term survival. However, there are conflicting results regarding long-term survival and functional recovery, particularly neurological outcome.
Conclusions: Research shows that epinephrine administration in patients with cardiac arrest increases the chance of restoring spontaneous circulation and patient survival to hospital admission and discharge. However, there are arguments questioning the validity of using epinephrine in resuscitation. Publications show that the compound contributes to post-resuscitation syndrome, which reduces a patient's chance of long-term survival. There are a number of conflicting studies that vary widely in the results presented. The current evidence is insufficient to either confirm or exclude the efficacy of epinephrine, which is why it is still recommended in the latest resuscitation guidelines by the European Resuscitation Council (ERC 2021) and the American Heart Association (AHA 2020).
The non-pharmacological treatment of primary dysmenorrhea - efficiency and safety
Authors: Zapała Brygida , Ząber Aldona , Gacoń Ewa , Zembala Julita , Siekierko Nikola , Kucharski Jakub , Żołnierek Maja , Kotusiewicz Wiktoria , Lewandowski Mateusz Mirosław 
Published: May 2023

Primary dysmenorrhea is the most common, though often underdiagnosed, gynecological disorder of women of reproductive age. The disease presents with painful abdominal cramps associated with menstrual bleeding in the absence of pelvic abnormalities. Symptoms are caused primarily by increased levels of prostaglandins produced by the endometrium, which provides hypercontraction of the uterine muscles, ischemia, and pain. Dysmenorrhea is usually treated pharmacologically with non-steroidal anti-inflammatory drugs or hormonal contraception. In particularly severe cases, surgical treatment is also possible. Nonetheless, an increasing amount of studies on non-pharmacological treatments have been published recently. Methods like Transcutaneous Electrical Nerve Stimulation (TENS), acupuncture, continuous topical heat, or exercise and yoga seem to be effective in reducing the symptoms of primary dysmenorrhea. All have an anti-inflammatory effect by lowering prostaglandin levels, but they also contribute to reducing symptoms through other mechanisms. TENS elevates the pain threshold and, together with acupuncture, causes the release of endogenous opioids. Heat, yoga, and acupuncture also lead to increased blood flow in the uterus, reducing hypoxia. Their additional advantage is the low cost and ease of self-use, except for acupuncture, depending on the patient's needs. Side effects of non-pharmacological treatments are usually mild and rarely reported.
Eklektyczna filozofia przyrody Krystyna Lacha
Authors: Roskal Zenon 
Published: May 2023

Filozofia Krystyna Lacha Szyrmy z uwagi na jej nominalnie eklektyczny charakter nie jest przedmiotem żywego zainteresowania historyków filozofii w Polsce. Krytyczne wydanie dzieł filozoficznych Szyrmy może zmienić ten stan rzeczy, ale w wydaniu tym pominięte zostały poglądy filozoficzne Szyrmy, które ujawnił w przypisach w redagowanym przez niego czasopiśmie Pamiętnik Umiejętności Moralnych i Literatury. W artykule zostały nie tylko przytoczone te poglądy, ale także zostały zinterpretowane jako frenologiczno-spirytualistyczny amalgamat, który łączy nowożytny empiryzm z dogmatyzmem scholastycznej metafizyki. Programowy eklektyzm tej filozofii został zinterpretowany jako postawa filozoficzna w pełni afirmującą dyspozycje do pozytywnej oceny takich wartości jak wybór, pluralizm i kompromis. Źródłem tego rodzaju eklektyzmu były doświadczenia życiowe Krystyna Lacha.