bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANFIS- and GEP-based model for prediction of scour depth around bridge pier in clear-water scouring and live-bed scouring conditions
Authors: Choudhary Amandeep , Das Bhabani Shankar , Devi Kamalini , Khuntia Jnana Ranjan 
Published: May 2023

Abstract
Scour depth prediction is an important aspect of designing a bridge pier structure in a river. Proper modeling of scour depth ensures the sustainability of the structure. An attempt is made to develop a scour depth model for the bridge pier using an adaptive network-based fuzzy inference system (ANFIS) and gene expression programming (GEP). The scour depth is found to be influenced by various independent parameters such as pier diameter, flow depth, approach mean velocity, critical velocity, Froude number, bed sediment, and geometric standard deviation of bed particle size. Gamma tests are performed to identify the best input parameter combinations to predict scour depth. In the present study, two separate models have been developed for clear-water scouring (CWS) and live-bed scouring (LBS). For different ranges of input parameters, the scour depth ratio is computed and error analysis is performed. Results indicate that the ANFIS model (R2CWS = 0.95, MAPECWS = 9.39% and R2LBS = 0.95, MAPELBS = 5.29%) is the most accurate predictive model in both scour conditions as compared to the GEP model and existing models of previous researchers. However, for the low value of pier diameter (b) to flow depth (y) ratio (&lt;0.25), the present ANFIS model apportioned unsatisfactory results for LBS only.
Diversity of blaPOM in carbapenem-resistant opportunistic pathogenic Pseudomonas otitidis in municipal wastewater
Authors: Di Doris Yoong Wen , Cao Guangxiang , Zhong Chuanqing , Yan Tao 
Published: May 2023

Abstract

Metallo-β-lactamases (MBLs) encoding carbapenem resistance in wastewater are a well-known serious threat to human health. Twelve Pseudomonas otitidis isolates obtained from a municipal wastewater treatment plant (WWTP) in Hawaii were found to possess a subclass B3 MBL – POM (P. otitidis MBL), with a minimum inhibition concentration (MIC) range of 8–16 mg/L. The unrooted neighbor-joining phylogenetic tree showed that these blaPOM genes isolated in wastewater samples (n = 12) were distinctly different from other reference genes isolated from clinical, freshwater, animal, and soil samples except for isolates MR7, MR8, and MR11. MR7, MR8, and MR11 were found to have 4, 3, and 3 amino acid substitutions when compared to the type strain MC10330T and were closely clustered to the clinical reference genes. The meropenem hydrolysis experiment showed that isolates with multiple amino acid substitutions completely hydrolyzed 64 mg/L of meropenem in 7 h. The emergence of the opportunistic pathogen P. otitidis chromosomally encoding blaPOM in the treated municipal wastewater is an alarming call for the spread of this MBL in the environment. Further studies are required to understand the mechanism and regulation of this carbapenem-resistant β-lactamase in order to fill in the knowledge gap.
Agricultural irrigation water price apportionment and sharing
Authors: Huang Yulin , Wang Shuangyin , Li Xin , Cheng Dongling , Wang Zhe , He Bingjing , Fan Ronxin 
Published: May 2023

Abstract

Studying the apportionment and sharing of agricultural water prices is necessary for clarifying the relationship between agricultural water price apportionment and government responsibility and ensuring the benign operation of irrigated areas. From the perspective of the versatility of irrigation water, irrigation benefits are classified as internal or external; the degree of benefit is measured using the proportion of irrigation water per cubic metre of internal and external benefits. This is used as an allocation coefficient to reasonably share prices based on farmers’ water price tolerance, build agricultural water price apportionment and sharing models, and calculate the range of water prices borne by farmers and the government in the Baojixia Irrigation District in the Shaanxi Province of China. Results showed that the apportionment coefficients of farmers and government were 0.85 and 0.15, respectively. For grain crops, the farmers' price range was 0.115–0.508 yuan/m3, while that of the government was 0.516–0.909 yuan/m3; for cash crops, these values were 0.566–3.009 and 0.154–0.458 yuan/m3, respectively. The results of this study support the formulation of agricultural water prices and provide a theoretical reference for reducing the water burden of farmers and promoting the high-quality development of the regional economy
PERFIL DE SERVIÇOS PÚBLICOS QUE REALIZAM AVALIAÇÃO DO FRÊNULO LINGUAL EM NEONATOS NO RIO GRANDE DO NORTE
Authors: Samara Raquel Sousa de Oliveira  , Monique Ramos Paschoal Dutra  
Published: May 2023

RESUMO
Introdução: A anquiloglossia é caracterizada pela alteração do frênulo lingual resultando na restrição dos movimentos da língua. A avaliação do frênulo lingual em neonatos é importante para diagnosticar precocemente essa alteração. Objetivo: Traçar perfil de serviços que realizam a avaliação do frênulo lingual em neonatos nos hospitais e maternidades públicas do estado do Rio Grande do Norte (RN). Metodologia: Trata-se de um estudo observacional, descritivo e transversal, com abordagem quantitativa. Foram incluídos na pesquisa as maternidades públicas e filantrópicas do estado do RN que realizam procedimentos obstétricos e assistência materno-infantil. As informações acerca da avaliação do frênulo lingual em neonatos e caracterização desses serviços foram coletadas por meio de um questionário eletrônico. Os dados foram armazenados em planilhas no Excel e analisados através do Statiscal Package Social Sciences (SPSS) versão 23.0, onde foram conduzidas análises das variáveis investigadas. Resultados: Participaram do estudo 23 hospitais e maternidades públicas do RN, na qual constatou-se que apenas 7 (30,44%) ofertam a avaliação do frênulo lingual em neonatos no próprio estabelecimento, as demais encaminham para outros serviços. O exame foi implantado nas maternidades entre os anos de 2014 e 2018. A quantidade de profissionais que realizam esta avaliação variou entre 1 e 9 por instituição, e os profissionais envolvidos foram os fonoaudiólogos e cirurgiões-dentistas. A prevalência da anquiloglossia variou de 3,7% a 14,5%. A maioria das maternidades realizam a frenotomia e o profissional que executa é o médico ou cirurgião-dentista. Conclusões: Constatou-se uma baixa oferta da avaliação do frênulo lingual em neonatos no próprio estabelecimento de nascimento. Além disso, essa oferta ainda não acontece de forma universal, principalmente no interior do estado do RN.
Palavras-Chave: Anquiloglossia, Programas Nacionais de Saúde, Triagem Neonatal.
DESAFIOS DO ATENDIMENTO NUTRICIONAL EM TEMPOS DE PANDEMIA: RELATO DE EXPERIÊNCIA
Authors: Silva Ellen Cristina , Araújo Daline Fernandes de Souza , Felicio Aurivânia Kyrlle Peixôto , Lucena Luanna Kássia Sousa de , Freitas Fernanda da Fonseca 
Published: May 2023

Introdução: Considerando o cenário de pandemia ocorrido nos últimos anos (2019- atual) em razão da grande propagação mundial do novo Coronavírus (SARS- CoV-2), tornaram-se necessárias medidas preventivas que corroborasse na diminuição do contágio e disseminação do vírus, dentre estas, o distanciamento social. Com isso, houveram muitas modificações e adaptações de protocolos assistenciais assim como no atendimento nutricional que, embasados em normativas do Conselho Federal de Nutricionistas por meio de resolução, permitiu a utilização do atendimento nutricional de maneira não presencial. Objetivo: Relatar a experiência e desafios vivenciados durante o componente curricular Terapia Ambulatorial Nutricional- Prática II, do curso de Nutrição, por meio de atendimentos nutricionais híbridos, considerando o contexto de pandemia. Metodologia: Trata-se de um relato de experiência construído a partir das vivências do componente curricular Terapia Ambulatorial Nutricional- Prática II (Módulo prático), que integra a grade do Curso de Nutrição, da Faculdade de Ciências da Saúde do Trairi- FACISA, da Universidade Federal do Rio Grande do Norte- UFRN, os atendimentos se passaram em um cenário de pandemia, demandando cuidados e alterações. Resultados: Percebeu-se a partir dessa vivência, que diante do cenário atual muitas adaptações precisaram ser realizadas, no entanto, a utilização de estratégias se fez bastante presente de modo que tornasse a proposta viável. Conclusões: São muitos os obstáculos enfrentados quanto ao atendimento nutricional no contexto de pandemia, haja vista que ajustes foram necessários no cronograma de consultas bem como limitações, os quais dificultaram muitas vezes a realização de uma abordagem igual à planejada. Porém, os obstáculos não tornaram inviável os atendimentos, de modo que foi possível atingir êxito nas consultas, metas e objetivos do paciente.
EDUCAÇÃO ALIMENTAR E NUTRICIONAL EM CASA: A EXPERIÊNCIA DO ENSINO REMOTO NA ESCOLA PÚBLICA EM MUNICÍPIO PARAIBANO
Authors: Ferreira Tavares Nonato Larissa , Evilys Dias da Silva Jhulia , Ramos de Araújo Raymme , Diniz Alves Maria das Graças , Bernardino Domingos José Douglas , Silva Freire de Souza Guilherme , De Araújo Palmeira Poliana , Macêdo Venâncio dos Santos Ana Beatriz 
Published: May 2023

Introdução: Às medidas de segurança da COVID-19 direcionaram a adoção do modelo remoto de ensino, inclusive para ações de extensão universitária realizadas no ambiente escolar. A extensão contribui para a promoção da saúde ao abordar temas como a Educação Alimentar e Nutricional (EAN). Objetivo: O objetivo deste trabalho é relatar a experiência da extensão universitária e a adaptação de ações de EAN ao modelo remoto, com escolares de ensino fundamental do interior da Paraíba em 2020. Metodologia: O projeto “#TICS: EAN em Casa foi realizado com escolares do ensino infantil ao 5º ano de uma escola pública de Cuité, Paraíba. Utilizou-se o whatsapp como ferramenta para as atividades baseadas no incentivo a brincadeiras com movimentação física, o desenvolvimento cognitivo, os vínculos intergeracionais e a alimentação de baixo custo. Foram desenvolvidas 12 ações, adaptadas à idade escolar e de fácil execução no domicílio, através de vídeos explicativos, plataforma de jogos e atividades impressas. Resultados: Observou-se os desafios: desigualdade no acesso à internet, fragilidade na manutenção do vínculo entre a equipe universitária com a comunidade escolar, sobrecarga dos professores e diversos contextos no ambiente familiar como, por exemplo, a vulnerabilidade social e violência doméstica. Conclusão: Contudo, é possível a realização da extensão universitária no modelo remoto a partir da diversificação de estratégias e ferramentas digitais, apesar dos desafios enfrentados para manter o vínculo entre equipe universitária-comunidade escolar.
Palavras-Chave: Educação Alimentar e Nutricional; Extensão Comunitária; Pandemia COVID-19; Tecnologia da Informação e Comunicação.
First Approval of Elacestrant as a Selective Estrogen Receptor
Degrader for the Treatment of Metastatic Breast Cancer
Authors: De Surya K. 
Published: May 2023

Abstract:
Elacestrant was approved by the US FDA on January 27, 2023, for treating
postmenopausal women or adult men with estrogen receptor (ER)-positive, HER2-
negative, ESR1-mutated advanced or metastatic breast cancer with disease progression
prior to using at least one line of endocrine therapy. In this short perspective, physicochemical
properties, dosage and administration, mechanism of action, pharmacodynamics,
pharmacokinetics, drug interaction, and treatment-related adverse reactions of elacestrant
are summarized.
Application of Network Pharmacology and Molecular Docking to Explore
the Mechanism of Danggui Liuhuang Tang against Hyperthyroidism
Authors: Song Dan , Yang Bin , Bao Wenzheng , Wang Jinglong 
Published: May 2023

Introduction:
To investigate the mechanism of Danggui Liuhuang Tang (DGLHT) in the
treatment of hyperthyroidism (HT), we explored the multi-component, multi-target, and multi-pathway
mechanism based on the network pharmacology method of traditional Chinese medicine.

Objective:
Using network pharmacology and molecular docking, the effective components, core targets,
and critical pathways of DGLHT in the therapy of HT were investigated. The mechanism of DGLHT in
the treatment of HT is discussed in this work, which also offers a scientific foundation for further research
into the process.

Methods:
To take DGLHT into the blood components as the research object, we used GeneCards, Drungbank,
Therapeutic Target Database (TTD), Online Mendelian Inheritance in Man (OMIM), Pharmacogenetics
and Pharmacogenomics Knowledge Base (PharmGKB), and other databases to predict the potential
target of the components. Then, it was integrated with the predicted targets of HT disease to obtain the
potential targets of DGLHT in the treatment of HT. We used String database and Cytoscape software for
protein-protein interaction network (PPI) construction, and DAVID platform for Gene Ontology (GO)
analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway annotation, the Cytoscape
software was used to construct a "component-target-pathway" network; the AutoDock Vina platform was
used to conduct molecular docking between the blood entry components and key targets.

Results:
According to the analysis, a total of 93 active ingredients, 348 disease-related targets, and 36 potential
targets were screened out. Among them, key targets such as MAPK1, CCND1, AKT1, and TNF
exert curative effects, and the main pathways are the HIF-1 signaling pathway, FoxO signaling pathway,
Chemokine signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, T cell receptor
signaling pathway, Jak-STAT signaling pathway, and other pathways. Molecular docking results
verified the interaction between active ingredients and key targets, among which rustication and quercetin
had high docking affinity with key target proteins MAPK1 and CCND1.

Conclusion:
This study preliminary revealed that DGLHT has the characteristics of multi-component,
multi-target, and multi-pathway in the treatment of HT, and it established a scientific foundation for a
more detailed investigation of DGLHT's molecular mechanism in the treatment of HT.
Domesticating Social Alarm Systems in Nursing Homes: Qualitative Study of Differences in the Perspectives of Assistant Nurses
Authors: Chang Fangyuan , Östlund Britt , Kuoppamäki Sanna 
Published: May 2023

BackgroundNew social alarm solutions are viewed as a promising approach to alleviate the global challenge of an aging population and a shortage of care staff. However, the uptake of social alarm systems in nursing homes has proven both complex and difficult. Current studies have recognized the benefits of involving actors such as assistant nurses in advancing these implementations, but the dynamics by which implementations are created and shaped in their daily practices and relations have received less attention.ObjectiveBased on domestication theory, this paper aims to identify the differences in the perspectives of assistant nurses when integrating a social alarm system into daily practices.MethodsWe interviewed assistant nurses (n=23) working in nursing homes to understand their perceptions and practices during the uptake of social alarm systems.ResultsDuring the four domestication phases, assistant nurses were facing different challenges including (1) system conceptualization; (2) spatial employment of social alarm devices; (3) treatment of unexpected issues; and (4) evaluation of inconsistent competence in technology use. Our findings elaborate on how assistant nurses have distinct goals, focus on different facets, and developed diverse coping strategies to facilitate the system domestication in different phases.ConclusionsOur findings reveal a divide among assistant nurses in terms of domesticating social alarm systems and stress the potential of learning from each other to facilitate the whole process. Further studies could focus on the role of collective practices during different domestication phases to enhance the understanding of technology implementation in the contexts of complex interactions within a group.
PERENCANAAN TEKNIS INSTALASI DAN KONTROL POMPA MOTOR INDUKSI PADA RESERVOIR SISTEM PENGOLAHAN AIR
Authors: Subairi Subairi , Hakim Ermanu Azizul 
Published: May 2023

Kebutuhan air bersih di suatu daerah menjadi sangat penting karena air merupakan kebutuhan pokok setiap mahluk hidup salah satu proses pengolahan air dikenal dengan sistem pengolahan air minum SPAM. Reservoir adalah tempat menampung sementara air hasil pengolahan untuk disalurkan pada konsumen. Dalam perencanaan teknis pembuatan reservoir adalah kontrol dan instalasi listrik pada unit pengolah ini, artikel ini membahas pada perencanaan teknis instalasi kelistrikan dan komponen pendukung seperti kontrol motor. Dari perencanaan teknis didapat bahwa motor pompa yang digunakan memiliki daya sebesar 125 kW, dari data ini didapat perencanaan kabel dan pengaman untuk istalasi dimana kabel pada panel utama LVMDP menggunakan kabel NYY 4x150 mm2dan pengaman arus lebih MCCB 300 ampere dan kontrol pada motor menggunakan komponen soft-starter. Kata kunci: IPA, SPAM, Reservoir,DesainTeknis,Soft Starter
EKSISTENSI IRIGASI D.I. NGUNUT KECAMATAN DANDER BERDASARKAN OPTIMASI KEUNTUNGAN TANAM
Authors: Yudha Prasetya David , Amal Andi Syaiful 
Published: May 2023

Indonesia merupakan salah satu negara agraris di dunia. Namun , tidak semua daerah mampu dengan maksimal menghasilkan sumber tanam sendiri. Salah satu daerah yang termasuk kurang produktif dalam pengembangan irigasi adalah Kabupaten Bojonegoro. Dengan kondisi topografi bebatuan dengan struktur geologi artiklin besar memanjang dari arah selatan ke utara . Hal ini mengindikasikan bahwa tanah di Kabupaten Bojonegoro cenderung terdiri dari bahan kapur yang kurang optimal untuk dijadikan sebagai lahan pertanian, sehingga dalam pemanfaatan air yang ada harus diimbangi dengan pengembangan luas lahan tanam yang optimal, sehingga diperoleh hasil analisa keuntungan hasil tanam yang maksimum.. Lokasi studi utama yang dibahas adalah Daerah Irigasi Ngunut, Kecamatan Dander, Kabupaten Bojonegoro, seluas 298 Ha, yang memanfaatkan air dari Sumber nggrogolan ( ngunut) sumber utama pemasok air. Diawali dengan analisa data sekunder untuk menentukan berapa kebutuhan air tanam dan air baku, mendapatkan debit sungai yang ada dan menentukan lahan tanam yang mungkin untuk dijadikan lahan pengembangan daerah irigasi eksisting. Optimasi yang dilakukan menggunakan metode linier dengan orientasi pada keuntungan maksimum setiap hektar tanam. Hasil analisa yang diperoleh adalah debit air yang tersedia diestimasi dengan metode Rasional selama 15 tahun, debit andalan terbesarnya adalah 5,156 m³/detik dan debit andalan terkecil adalah sebesar 0,000 m³/detik. Luas lahan yang dianjurkan sebagai dasar perencanaan pengembangan lahan tanam lahan hasil Optimasi Tanam 4 seluas 1040,147 Ha dengan keuntungan bersih tahunan per hektar sebesar Rp48.728.987. Kata Kunci—Ekstensifikasi Irigasi, Optimasi Tanam.
MODEL PENANGGULANGAN PENCEMARAN UDARA PADA MESIN ASPHAL MIXING PLANT
Authors: Romadhon Romadhon , Mokhtar Ali 
Published: May 2023

Analisis dampak lingkungan atas aktivitas mesin AMP terhadap kualitas udara di lingkungan industri kontruksi terpadu perlu dilakukan sehingga pengendalian pencemaran udara sesuai dengan ketentuan yang diijinkan. Sebab kondisi yang ada diindikasikan bahwa Industri Konstruksi Terpadu di Kabupaten Kediri belum melakukan pengolahan dampak untuk meminimalisir pencemaran udara yang terjadi atas aktivitas mesin AMP tersebut. Rumusan tujuan penelitian ini yaitu Untuk mengkontruks model penanggulangan pencemaran udara yang timbul atas aktivitas mesin Asphalt Mixing Plant (AMP) yang efisien dan efektif di Kecamatan Grogol, Kabupaten Kediri. Metode penelitian yang digunakan adalah metode penelitian kuantitatif, Teknik analisis data menggunakan SEM. hasil penelitian menemukan dua persamaan yaitu model matematisnya sebagai berikut ini: Y1 = -0,098 X1 – 0,244 X2 – 0,648X3 dan Y2 = 0,044 X1 + 0.181 X2 + 0,053 X3 dengan makna Semakin tinggi Aktivitas Pabrik AMP, Semakin tinggi konsentrasi polutan pencemaran udara dan Semakin besar dampak pencemaran udara. Ataupun sebaliknya. Meski didapatkan jujga hasil bahwa aktivitas mesin AMP tidak begitu besar pengaruhnya dalam peningkatan model strategi penanggulangan dampak udara tetapi memiliki andil untuk menentukan kualitas udara. Sehingga yang di maksud dengan pengurangan Aktivitas mesin AMP yaitu upaya yang diperlukan untuk melakukan pengaturan waktu operasi kerja secara efektif dan efiesien. Sehingga kemi merekomendasikan pada penelitian selanjtnya agar dapat menguji efek kausal variabel yang kami gunakan dalam penelitian ini kemudian ada beberapa hal untuk di bertimbakan yaitu etika bisnis, tekanan kelembagaan, kepemimpinan, budaya organisasi atau masalah sumber daya manusia.
ANALISIS MANAJEMEN RISIKO PEMBANGUNAN PASAR RAKYAT TROWULAN KABUPATEN MOJOKERTO
Authors: Siswo Siswo , Amal Andi Syaiful 
Published: May 2023

Manajemen risiko dalam pembangunan bangunan gedung menjadi penting untuk dilakukan. Dengan melakukan manajemen risiko diharapkan pembangunan infrastruktur gedung terwujud sasaran proyek yang tepat biaya, tepat waktu, dan tepat mutu. Salah satu risiko yang terjadi adalah keterlambatan pekerjaan proyek. Pekerjaan pembangunan Pasar Rakyat Trowulan Kabupaten Mojokerto sesuai dengan waktu kontrak yang telah disepakati, yaitu selama 240 hari pada pelaksanaannya mengalami keterlambatan. Penyebab keterlambatan bisa karena lokasi site yang sulit, cuaca, ketersediaan material, kekurangan tempat penyimpanan material, peralatan utama yang sering mengalami kemacetan dalam penggunaannya, maupun dikarenakan adanya gangguan lingkungan. Oleh karena itu, analisis risiko dalam pembangunan Pasar Rakyat Trowulan Kabupaten Mojokerto menjadi penting untuk dilakukan. Dengan melakukan manajemen risiko diharapkan pembangunan pasar dapat terwujud sasaran proyek yang tepat biaya dan waktu. Hasil penelitian adalah setelah dilakukan pengelompokkan risiko dengan menggunakan Probability Impact Matrix, didapatkan 11 risiko yang termasuk risiko tinggi, 3 risiko yang termasuk sedang, 6 risiko yang termasuk rendah dan 7 risiko yang termasuk sangat rendah. Faktor yang mempengaruhi risiko tinggi adalah faktor material dan peralatan, serta faktor kontraktual. Faktor yang mempengaruhi risiko sedang adalah faktor tenaga kerja serta faktor material dan peralatan. Faktor yang mempengaruhi risiko sedang dan rendah adalah faktor force majeur, faktor material dan peralatan, faktor faktor tenaga kerja
Concerns about cancer recurrence in Mexican women breast cancer survivors. Psychometric properties of the CARS scale
Authors: Ramírez-Orozco Mónica , Rojas-Russell Mario Enrique , Galindo-Vázquez Oscar , Robles-García Rebeca , Costas-Muñíz Rosario , Bargallo-Rocha Juan Enrique , Meneses-García Abelardo 
Published: May 2023

Fear of recurrence is one of the main affectations of cancer survivors. In Latin-American exist a lack of evidence on the subject and of valid instruments to measure it. The objective of this study was to determine the psychometric properties of the Concerns About Recurrence Scale in Mexican breast cancer survivors. An instrumental study was carried out with 200 women breast cancer survivors with a mean age of 53 years old and a mean survival of 52.5 months. A confirmatory factor analysis of the original version of the scale identified four factors that explained 77 % of the variance and satisfactory goodness of fit indicators: CFI = .967, TLI = .957, SRMR = .035, RMSEA = .071 as well as high internal consistency α = .945. Significant associations were also identified between general fear subscale, anxiety subscale of the HADS and total HADS score (r = .638 and r = .607; p = .01). The CARS presented adequate validity, reliability and factorial structure. It is recommended for usage in clinical care and research with Mexican breast cancer survivors.