bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neurodevelopment of babies born to mothers with epilepsy: A prospective observational cohort study
Authors: Bromley Rebecca L. , Bullen Philip , Campbell Ellen , Craig John , Ingham Amy , Irwin Beth , Jackson Cerain , Kelly Teresa , Morrow James , Rushton Sarah , García‐Fiñana Marta , Hughes David M. , Winterbottom Janine , Wood Amanda , Yates Laura M. , Clayton‐Smith Jill ,   the NaME Study Group
Published: July 2023

AbstractObjectiveDespite widespread monotherapy use of lamotrigine or levetiracetam during pregnancy, prospectively collected, blinded child development data are still limited. The NaME (Neurodevelopment of Babies Born to Mothers With Epilepsy) Study prospectively recruited a new cohort of women with epilepsy and their offspring for longitudinal follow‐up.MethodsPregnant women of <21 weeks gestation (n = 401) were recruited from 21 hospitals in the UK. Data collection occurred during pregnancy (recruitment, trimester 3) and at 12 and 24 months of age. The primary outcome was blinded assessment of infant cognitive, language, and motor development on the Bayley Scales of Infant and Toddler Development (3rd edition) at 24 months of age with supplementary parent reporting on the Vinelands Adaptive Behavior Scales (2nd edition).ResultsThere were 394 live births, with 277 children (70%) completing the Bayley assessment at 24 months. There was no evidence of an association of prenatal exposure to monotherapy lamotrigine (−.74, SE = 2.9, 95% confidence interval [CI] = −6.5 to 5.0, p = .80) or levetiracetam (−1.57, SE = 3.1, 95% CI = −4.6 to 7.7, p = .62) with poorer infant cognition, following adjustment for other maternal and child factors in comparison to nonexposed children. Similar results were observed for language and motor scores. There was no evidence of an association between increasing doses of either lamotrigine or levetiracetam. Nor was there evidence that higher dose folic acid supplementation (≥5 mg/day) or convulsive seizure exposure was associated with child development scores. Continued infant exposure to antiseizure medications through breast milk was not associated with poorer outcomes, but the number of women breastfeeding beyond 3 months was low.SignificanceThese data are reassuring for infant development following in utero exposure to monotherapy lamotrigine or levetiracetam, but child development is dynamic, and future follow‐up is required to rule out later emerging effects.
Parenting during the COVID‐19 pandemic: Insecure or unresolved attachment representation is a risk factor for harmful parenting behavior
Authors: Köhler‐Dauner Franziska , Ziegenhain Ute , Kipping Miriam , Mayer Inka , Fegert Jörg M. , Buchheim Anna 
Published: July 2023

AbstractBackgroundThe current COVID‐19‐pandemic confronted a large number of young families with stressors. For mothers with a history of childhood maltreatment (CM), the distress during the current pandemic added to their already increased risk for a less sensitive, maltreating parenting behavior.ObjectiveThis study aims to investigate whether maternal attachment representation mediates the relationship between maternal CM experiences and changes in parenting behavior during the pandemic.MethodAs a part of a longitudinal study, mothers' experiences of CM and their attachment status were assessed. For the present study, 92 mothers (mean age: 38.14 years, SD = 4.08; attachment representation: 36% secure, 64% insecure and unresolved) completed an online SARS‐CoV‐2‐pandemic survey assessing their parenting behavior since the beginning of the pandemic.ResultsThe odds of an insecure maternal attachment representation in adulthood increased with higher levels of CM load. Mediation analyses revealed that maternal attachment representation fully explained the relationship between maternal CM load to changes in sensitive, endangering, and overall parenting quality.ConclusionsCM has lasting effects on maternal adult attachment representations. Mothers' attachment representations contribute to a further understanding of intergenerational transmission mechanisms of CM later in adulthood through a more endangered parenting approach in challenging times.ImplicationsThe results of this study should be considered in the development of programs offered to families facing stressful circumstances. In particular, we recommend increased implementation of telephone‐ or web‐based programs.
Sentimental Sustainability: Does What Companies Say Tell More Than What Companies Do?
Authors: Ignatov Konstantin , Rudolf Markus 
Published: July 2023

AbstractBased on a sample of more than eleven thousand unique 10‐K reports of US companies filed with SEC in period 2013 to 2018, this study examines the relationship between actual sustainability performance of companies, evaluated by MSCI ESG performance scores, and the extent and the scope of environmental, social, and governance information disclosure in their annual reports. The study shows empirical evidence supporting the signalling theory view of voluntary disclosure of ESG information in annual reports for most industries, while environmentally unfriendly companies belonging to the Mining industry division show excessive reporting behavior favoring environmental topics, which is consistent with incentives to improve public image and mitigate social, political, and legal risks in line with the legitimacy theory of information disclosure. When differentiating between forward‐looking and non‐forward‐looking ESG statements, the study shows that companies providing more forward‐looking ESG information in annual reports show better next‐year ESG performance. This study implements established content analysis techniques with focus on ESG reporting and performance, building up on the study of Baier, Berninger, and Kiesel (2020) that proposed an ESG‐tailored dictionary for textual analysis purposes.
The impact of early adversity and education on genetic and brain morphological predictors of cognitive ability
Authors: Corley Emma , Fahey Laura , Fitzgerald Joan , Holleran Laurena , Walton Esther , Morris Derek W. , Donohoe Gary 
Published: July 2023

AbstractCognitive ability is a strong predictor of occupational achievement, quality of life and physical health. While variation in cognition is strongly heritable and has been robustly associated with early environment and brain morphology, little is known about how these factors combine and interact to explain this variation in cognition. To address this, we modelled the relationship between common genetic variation, grey matter volume, early life adversity and education and cognitive ability in a UK Biobank sample ofN = 5237 individuals using structural equation modelling. We tested the hypotheses that total grey matter volume would mediate the association between genetic variation and cognitive ability, and that early life adversity and educational attainment would moderate this relationship. Common genetic variation, grey matter volume and early life adversity were each significant predictors in the model, explaining ~15% of variation in cognitive ability. Contrary to our hypothesis, grey matter volume did not mediate the relation between genetic variation and cognition performance. Neither did early life adversity or educational attainment moderate this relation, although educational attainment was observed to moderate the relationship between grey matter volume and cognitive performance. We interpret these findings in terms of the modest explanatory value of currently estimated polygenic scores accounting for variation in cognitive performance (~5%), making potential mediating and moderating variables difficult to confirm.
CHRONOCENOSIS: HOW TO IMAGINE THE MULTIPLICITY OF TEMPORALITIES WITHOUT LOSING THE EMPHASIS ON POWER AND CONFLICTS
Authors: Pernau Margrit 
Published: July 2023

ABSTRACTThe twentieth century witnessed the historicization of the categories of time and space. Instead of functioning as a universal category, moving from the past to the present and from the present to the future, time has multiplied into temporalities, and historians have looked for adequate metaphors to describe this multiplicity, its many ways of moving forward and backward, its acceleration and decelerations, its entanglements, and its conflicts and struggles for hegemony. The editors of Power and Time: Temporalities in Conflict and the Making of History offer a thought‐provoking concept by translating biocenosis, the coexistence of different species in the same environment, to time studies and thus using the term “chronocenosis” to refer to different temporalities sharing the same embattled space. The volume covers a large variety of case studies—ranging from early modern Chinese historical novels to attempts to bring together social and biological time in the discussion of the Anthropocene—and draws together disciplines that are not usually discussed in studies of temporalities, disciplines ranging from law to the history of science.
Periradicular surgery: A longitudinal registry study of 10‐year outcomes and factors predictive of post‐surgical extraction
Authors: de Almeida Fernando José Mota , Dawson Victoria S. , Kvist Thomas , Frisk Fredrik , Bjørndal Lars , Isberg Per‐Erik ,   EndoReCo, Fransson Helena 
Published: July 2023

AbstractAimThis historical prospective cohort study of the adult population of Sweden is based on data from a national registry: the primary aim was to evaluate the long‐term survival of teeth after periradicular surgery. A secondary aim was to identify factors predictive of extraction within 10 years of registration of periradicular surgery.MethodologyThe cohort consisted of all individuals who had undergone periradicular surgery to treat apical periodontitis, as reported to the Swedish Social Insurance Agency (SSIA) in 2009. The cohort was followed until 31 December 2020. Subsequent registrations of extractions were collected for Kaplan–Meier survival analyses and survival tables. The patients' sex, age, dental service provider and tooth group were also retrieved from SSIA. Only one tooth per individual was included in the analyses. Multivariable regression analysis was used and p < .05 was considered statistically significant. The reporting guidelines STROBE and PROBE were followed.ResultsAfter data cleaning, and exclusion of 157 teeth, 5622 teeth/individuals remained for analysis. The mean age of the individuals at the time of the periradicular surgery was 60.5 years (range 20–97, standard deviation 13.31); 55% were women. At the end of the follow‐up, that is, up to 12 years, a total of 34.1% of the teeth had been reported as extracted. The multivariate logistic regression analysis, based on follow‐up data at 10 years after registration of the periradicular surgery, included 5548 teeth, of which 1461 (26.3%) had been extracted. Significant associations between the independent variables tooth group and dental care setting (both p < .001) and the dependent variable extraction were found. The highest odds ratio (OR) for extraction applied to tooth group: compared to maxillary incisors and canines, mandibular molars were at greatest risk of extraction (OR 2.429, confidence interval 1.975–2.987, p < .001).ConclusionsAfter periradicular surgery in predominantly elderly people in Sweden, approximately three‐quarters of the teeth are retained over a 10‐year period. The type of tooth is associated with extraction: mandibular molars are at greater risk of extraction than maxillary incisors and canines.
MicroRNA‐4691‐3p inhibits the inflammatory response by targeting STING in human dental pulp cells: A laboratory investigation
Authors: Tian Xinxin , Zhang Ping , Liu Fei , Yang Lijie , Fu Kun , Gan Kang , Liu Chao 
Published: July 2023

AbstractAimThe regulation of human dental pulp inflammation is not fully understood. This study aims to investigate the effect of miR‐4691‐3p on the cGAS–STING signalling cascade and its downstream cytokines production in human dental pulp cells (HDPCs).MethodologyNormal dental pulp tissue and pulp tissue with irreversible pulpitis from third molars were collected. HDPCs were isolated from pulp tissue. The expression of STING mRNA and miR‐4691‐3p was measured by quantitative real‐time PCR. Bioinformatic computation via TargetScanHuman 8.0 and a luciferase reporter assay was used to identify the targets of miR‐4691‐3p. A miR‐4691‐3p mimic and inhibitor were used to upregulate or downregulate miR‐4691‐3p expression in HDPCs. HDPCs were transfected with c‐di‐AMP, c‐di‐GMP, cGAMP, interferon stimulatory DNA (ISD) and bacterial genomic DNA. Immunoblot was performed to detect the phosphorylation of TBK1, p65 and IRF3. Enzyme‐linked immunoassay was performed to detect the cytokines including IFN‐β, TNF or IL‐6 downstream of cGAS–STING.ResultsMiR‐4691‐3p expression was increased in human dental pulp tissue with irreversible pulpitis. Treatment of HDPCs using recombinant human IFN‐β, TNF or IL‐6 also upregulated miR‐4691‐3p. The bioinformatic prediction and luciferase reporter assay confirmed that STING was a direct target of miR‐4691‐3p. The miR‐4691‐3p mimic suppressed STING expression, the phosphorylation of TBK1, p65 and IRF3, and the IFN‐β, TNF or IL‐6 production. In contrast, the miR‐4691‐3p inhibitor enhanced the STING expression, the phosphorylation of TBK1, p65 and IRF3 and the IFN‐β, TNF or IL‐6 production.ConclusionsMiR‐4691‐3p negatively regulates the cGAS–STING pathway by directly targeting STING. This provides insight to utilize miRNA‐dependent regulatory effect to treat endodontic disease as well as STING‐dependent systemic inflammatory disease.
HOUSEHOLD INVENTORY, TEMPORARY SALES, PRICE INDICES
Authors: Ueda Kozo , Watanabe Kota , Watanabe Tsutomu 
Published: July 2023

AbstractThis study addresses the large bias in chained price indices that persists even at lower frequencies. The bias arises from intertemporal substitution caused by consumer hoarding, and is problematic for purchase‐based data. In order to resolve this issue, we propose a method for calculating changes in inventories and consumption using retailer scanner data. We construct a partial equilibrium model to estimate inventories and consumption and show that the model accurately predicts the sign and size of the bias. We also demonstrate that the bias is smaller for consumption‐based data and propose a particular type of price index that eliminates intertemporal substitution bias.
When East meets West: A practitioner inquiry of culturally responsive pedagogy in an Australian Chinese as a Foreign Language classroom
Authors: Xu Wen 
Published: July 2023

AbstractA nuanced description of “what” (the curriculum) and “how” (the pedagogy) to teach in Chinese as a Foreign Language (CFL) education remains unexplored in existing scholarship. This paper addresses this paucity by undertaking a practitioner inquiry to explore the intersection of Eastern pedagogy and Western students in an Australian CFL classroom, with the aim of improving classroom practice and enhancing low socio‐economic status (SES) students’ learning experiences. Ten language lessons were segmented into phases and analyzed within the parameter of classification and framing theorized by Bernstein. An analysis of research journals and students’ focus groups shows culturally responsive pedagogy integrating constructivist and traditional Chinese approaches to teaching has the potential of inducting underprivileged students into knowledge about curriculum and language, providing them with linguistic capital and high aspirations for the future. Pedagogically, this article offers insights for CFL teachers to mediate Chinese and Western teaching beliefs and education schemas; practically, the findings glimpse the ways in which CFL education can be discursively constructed as a cultural agenda that (re)shapes the educational experiences of underprivileged students and mobilizes them into critical hopes that can be acted upon. This paper has important implications for foreign language theory building and for responding to the “back to basics” curriculum approach in schools serving disadvantaged communities.
Review on microalgae protein and its current and future utilisation in the food industry
Authors: Bhatnagar Pooja , Gururani Prateek , Singh Narpinder , Gautam Pankaj , Vlaskin Mikhail S. , Kumar Vinod 
Published: July 2023

SummaryMicroalgae, the photosynthetic microorganisms, open novel commercial opportunities for developing new products because of their abundance in protein, carbohydrates, pigments, vitamins and minerals. These microorganisms possess several advantages such as rapid growth, minimal land and water requirements and adaptability to various environmental conditions. As concerns arise regarding the ability of animal and plant‐based sources to meet future protein demands, researchers have turned their attention to microalgae like Spirulina and Chlorella for various applications. Microalgae typically contain around 30% protein and in case of few cyanobacteria it can reach up to 55%–60%, surpassing the protein content of conventional sources. Numerous studies have investigated the utilisation of algal biomass to enhance the protein content of a wide range of food products, including cookies, bread, yoghurt, snacks, dairy alternatives and soups. This comprehensive review aims to provide a systematic exploration of microalgae protein and its current and future utilisation in the food industry.
Multicentre verification of haematology laboratory blood collection tubes during a global blood collection tube shortage
Authors: Nell Erica‐Mari , Bailly Jenique , Oelofse Diana , Linström Michael , Opie Jessica , Chapanduka Zivanai Cuthbert , Vreede Helena , Korf Marizna 
Published: July 2023

AbstractIntroductionVerification of blood collection tubes is essential for clinical laboratories. The aim of this study was to assess performance of candidate tubes from four alternative suppliers for routine diagnostic haematology testing during an impending global shortage of blood collection tubes.MethodsA multicentre verification study was performed in Cape Town, South Africa. Blood from 300 healthy volunteers was collected into K2EDTA and sodium citrate tubes of BD Vacutainer® comparator tubes and one of four candidate tubes (Vacucare, Vacuette®, V‐TUBE™ and Vacutest®). A technical verification was performed, which included tube physical properties and safety. Routine haematology testing was performed for clinical verification.ResultsVacucare tubes did not have a fill‐line indicator, Vacuette® tubes had external blood contamination on the caps post‐venesection and Vacutest® tubes had hard rubber stoppers. K2EDTA tubes of Vacuette®, Vacucare and Vacutest® performed similarly to the comparator. Unacceptable constant bias was seen for PT in Vacucare (95% CI −2.38 to −0.10), Vacutest® (95% CI −1.91 to −0.49) and Vacuette® (95% CI 0.10–1.84) tubes and for aPTT in Vacuette® (95% CI 0.22–2.00) and V‐TUBE™ (95% CI −2.88 to −0.44). Unacceptable %bias was seen for aPTT in Vacucare (95% CI 2.78–4.59) and Vacutest® tubes (95% CI 2.53–3.82; desirable ±2.30), and in V‐TUBE™ for mean cell volume (95% CI 1.15–1.47, desirable ±0.95%) and mean cell haemoglobin concentration (95% CI −1.65 to −0.93, desirable ±0.43%).ConclusionBlood collection tubes introduce variability to routine haematology results. We recommend that laboratories use one brand of tube. Verification of new candidate tubes should be performed to ensure consistency and reliable reporting of results.
Influences of risk‐aversion behavior and purchasing option in a cross‐border dual‐channel supply chain
Authors: Chen Xue , Li Bo , Song Dongping , Wang Minxue 
Published: July 2023

AbstractConsidering the rapid development of cross‐border e‐commerce, this paper constructs a cross‐border dual‐channel supply chain with a supplier and a retailer in different countries. The supplier directly sells products to overseas market through an online channel and a retail channel. Since the supplier expands the overseas market and bears the potential risk of exchange rate volatility, the supplier is risk‐averse. In the presence of exchange rate volatility, the risk‐averse supplier decides whether to purchase an option to hedge against the risk of exchange rate volatility. Conditional value at risk is applied as a measure of the supplier's risk‐averse behavior. To identify the conditions under which the risk‐averse supplier should purchase an option, we analyze two scenarios: the benchmark model and the option model. By comparing the benchmark model with the option model, we show that if the option premium is lower than a threshold, the risk‐averse supplier prefers to purchase an option, which also makes the retailer better off. Interestingly, when the supplier becomes less risk‐averse, as the exchange rate volatility increases, both players benefit a higher utility in the option model. Finally, we verify the results’ robustness using numerical analysis.
Research Review: Siblings matter. A multi‐level meta‐analysis on the association between cannabis use among adolescent siblings
Authors: Defoe Ivy N. , Treffers Sanne , Stams Geert Jan 
Published: July 2023

BackgroundParents' and peers' cannabis use are well‐documented predictors of youth cannabis use, however, relatively little is known about the influence of siblings' cannabis use. Hence, this meta‐analysis investigated the association between sibling‐youth cannabis use (disorder) and explored moderation by sibling type (monozygotic‐ vs. dizygotic‐ vs. non‐twins), age, age spacing, birth order, gender, and gender constellations (same‐ vs. mix‐ gender pairs). When comparison data of parents' and peers' cannabis use (disorder) were also available in the included studies, separate meta‐analyses on associations between parent‐youth and peer‐youth cannabis use (disorder) were additionally conducted.MethodsStudies were selected if they included 11‐ to 24‐year‐old participants, and investigated associations between cannabis use (disorder) among those youth and their siblings. These studies were retrieved via a search in seven databases (e.g., PsychINFO). A multi‐level meta‐analysis using a random effects model was performed on the studies, and heterogeneity analyses and moderator analyses were also conducted. PRISMA guidelines were followed.ResultsWe retrieved 20 studies (most of which originated from Western cultures) with 127 effect sizes for the main sibling‐youth meta‐analysis and found a large overall effect‐size (r = .423), implying that youth had higher cannabis use rates when their sibling used cannabis, and this association was stronger for monozygotic twins and for same‐gender sibling pairs. Finally, a medium effect size existed for the associations between parent‐youth cannabis use (r = .300) and a large effect size for peer‐youth cannabis use (r = .451).ConclusionsYouth are more likely to use cannabis when their siblings use cannabis. This sibling‐youth cannabis use association existed for all sibling constellations, was larger than the association between parent‐youth cannabis use, and was similar in magnitude compared to the association between peer‐youth cannabis use—suggesting both genetic and environmental influences (e.g., social‐learning) between siblings. Hence, it is important not to neglect sibling influences when treating youth cannabis use (disorder).