bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcriptome profiling reveals the expression and regulation of genes associated with Fusarium wilt resistance in chickpea (Cicer arietinum L.)
Authors: Garg Vanika , Chitikineni Annapurna , Sharma Mamta , Ghosh Raju , Samineni Srinivasan , Varshney Rajeev K. , Kudapa Himabindu 
Published: May 2023

AbstractFusarium wilt (FW) is one of the most significant biotic stresses limiting chickpea production worldwide. To dissect the molecular mechanism of FW resistance in chickpea, comparative transcriptome analyses of contrasting resistance sources of chickpea genotypes under control and Fusarium oxysporum f. sp. ciceris (Foc) inoculated conditions were performed. The high‐throughput transcriptome sequencing generated about 1137 million sequencing reads from 24 samples representing two resistant genotypes, two susceptible genotypes, and two near‐isogenic lines under control and stress conditions at two‐time points (7th‐ and 12th‐day post‐inoculation). The analysis identified 5182 differentially expressed genes (DEGs) between different combinations of chickpea genotypes. Functional annotation of these genes indicated their involvement in various biological processes such as defense response, cell wall biogenesis, secondary metabolism, and disease resistance. A significant number (382) of transcription factor encoding genes exhibited differential expression patterns under stress. Further, a considerable number of the identified DEGs (287) co‐localized with previously reported quantitative trait locus for FW resistance. Several resistance/susceptibility‐related genes, such as SERINE/THREONINE PROTEIN KINASE, DIRIGENT, and MLO exhibiting contrasting expression patterns in resistant and susceptible genotypes upon Foc inoculation, were identified. The results presented in the study provide valuable insights into the transcriptional dynamics associated with FW stress response in chickpea and provide candidate genes for the development of disease‐resistant chickpea cultivars.
The comparative study of biocomposites based on hydrochar and chitosan‐modified urea‐formaldehyde resins
Authors: Ristić Mirjana , Samaržija‐Jovanović Suzana , Jovanović Vojislav , Kostić Marija , Jovanović Tijana , Marković Gordana , Kojić Marija , Vujčić Ivica , Marinović‐Cincović Milena 
Published: May 2023

AbstractTo provide new insight into the field of urea‐formaldehyde (UF) adhesives science, in this work, for the first time, UF resin was modified with hydrochar of spent mushroom substrate (HCUF) and chitosan (CHUF) to investigate the effect of these bio‐fillers on the hydrolytic and thermal stability of in situ prepared UF resins. The characterization of the modified UF biocomposites was performed using X‐ray diffraction analysis (XRD), Fourier transforms infrared spectroscopy (FTIR), non‐isothermal thermogravimetric analysis (TG), differential thermal gravimetry (DTG), and differential thermal analysis (DTA). Scanning electron micrographs (SEM) of the CHUF and HCUF biocomposites show a spherical structure that differs from each other because the surface of the CHUF biocomposite has pronounced pores that form a network structure. With its hydroxyl and amino groups, chitosan bonding to UF resin through hydrogen bonds, which is confirmed by FTIR analysis. The content of free FA in CHUF biocomposite is 0.06%, while that of HCUF is higher and amounts to 0.48%. The content of released FA in both modified UF biocomposites was similar (2.5% and 2.8% for CHUF and HCUF, respectively). The hydrolytic stability of CHUF is slightly higher compared to the HCUF biocomposite. Thermal analysis shows that the CHUF is thermally more stable because it starts to decompose at a slightly higher temperature than the HCUF biocomposite.
The Plight of Temporary Migrants: The Intersection of Migration Status, Family Violence and Support
Authors: Pfitzner Naomi , Fitz-Gibbon Kate , Walklate Sandra , Meyer Silke , Segrave Marie 
Published: May 2023

AbstractThere is a growing body of research showing that migration status can exacerbate the risk of DFV, and that targeted support is required for migrant and refugee women. Given this knowledge, the impact of COVID-19 lockdowns and stay-at-home orders for women holding temporary visas requires specific and focused attention. This chapter explores the differential impact of migration status on women’s experiences of DFV during the COVID-19 pandemic, drawing on 100 victim-survivor case files during the national lockdown in Australia in March 2020. This chapter illustrates the importance of paying close attention to the experiences and responses to DFV and the broader treatment of temporary migrants in the COVID-19 context.
In the Shadow of COVID-19: The Invisibility of Children’s Experiences of Violence in Homes During the Pandemic
Authors: Pfitzner Naomi , Fitz-Gibbon Kate , Walklate Sandra , Meyer Silke , Segrave Marie 
Published: May 2023

AbstractThe invisibility of children and their wellbeing during the COVID-19 pandemic became an early issue of global concern. The UN and specialist children’s services raised concerns at the outset of the pandemic that children may be the biggest victims of COVID-19 restrictions, due to their exacerbated vulnerability and invisibility associated with added household stressors and wide-ranging closures of education and childcare settings. Despite this, globally the policy discourse around violence in the home and the role of pandemic-related restrictions in increased risk and decreased detection remained overwhelmingly adult-focused. This chapter explores children’s experiences and their invisibility throughout the first two years of the pandemic. Emerging evidence highlights the critical need to ensure attention is paid to children’s experiences of violence in the home during the pandemic, and to their related recovery needs going forward.
Conclusion
Authors: Pfitzner Naomi , Fitz-Gibbon Kate , Walklate Sandra , Meyer Silke , Segrave Marie 
Published: May 2023

AbstractThis conclusion examines what lessons, if any, can be drawn from adaptations to service delivery and responses during COVID-19 for future policy responses to global and local challenges faced in times of crisis. This chapter draws the book together—paying particular attention to the ways in which the first two years of the COVID-19 pandemic further marginalised certain groups, including women and children who experience domestic and family violence. During this time, the conditions of the global health crisis compounded the already existing impacts of structural inequality. This chapter serves as a ‘call to action’ for governments worldwide to prioritise women and children’s safety and freedom from violence, as governments continue to respond to COVID-19 and other crises. It makes the case that for recovery from a crisis to work, the gendered structural inequalities documented in this book must be front and centre in any policy priorities going forward.
Digital Technology-Driven Business Process Redesign: A Classification Framework
Authors: Kubrak Kateryna , Milani Fredrik , Nava Juuli 
Published: May 2023

AbstractOrganizations constantly seek ways to improve their business processes. This often involves using digital technologies to enable process improvements. However, simply substituting existing technology with newer technology has limited value as compared to using the capabilities of digital technologies to introduce changes to business processes. Therefore, process analysts need to understand how the capabilities of digital technologies can be used to redesign business processes. In this paper, we conducted a systematic literature review and examined 40 case studies where digital technologies were used to redesign business processes. We identified that, within the context of business process improvement, capabilities of digitalization, communication, analytics, digital representation, and connectivity can enable business process redesign. Furthermore, we note that these capabilities enable applying nine redesign heuristics. Based on our review, we map how each capability can facilitate the implementation of specific redesign heuristics to improve a business process. Thus, our mapping can aid analysts in identifying candidate redesigns that capitalize on the capabilities of digital technologies.
Persuasive Visual Presentation of Prescriptive Business Processes
Authors: Leemets Janna-Liina , Kubrak Kateryna , Milani Fredrik , Nolte Alexander 
Published: May 2023

AbstractPrescriptive process monitoring methods recommend interventions during the execution of a case that, if followed, can improve performance. Research on prescriptive process monitoring so far has focused mainly on improving the underlying algorithms and providing suitable explanations for recommendations. Empirical works indicate, though, that process workers often do not follow recommendations even if they understand them. Drawing inspiration from the field of persuasive technology, we developed and evaluated a visualization that nudges process workers towards accepting a recommendation, following a design science approach. Our evaluation points towards the feasibility of the visualization and provides insights into how users perceive different persuasive elements, thus providing a basis for the design of future systems.
Normalized Solutions to the Fractional Schrödinger Equation with Potential
Authors: Zuo Jiabin , Liu Chungen , Vetro Calogero 
Published: May 2023

AbstractThis paper is concerned with the existence of normalized solutions to a class of Schrödinger equations driven by a fractional operator with a parametric potential term. We obtain minimization of energy functional associated with that equations assuming basic conditions for the potential. Our work offers a partial extension of previous results to the non-local case.
Neutrophil sub-types in maintaining immune homeostasis during steady state, infections and sterile inflammation
Authors: Ganesh Kailash , Joshi Manjunath B. 
Published: May 2023

Abstract
Introduction
Neutrophils are component of innate immune system and a) eliminate pathogens b) maintain immune homeostasis by regulating other immune cells and c) contribute to the resolution of inflammation. Neutrophil mediated inflammation has been described in pathogenesis of various diseases. This indicates neutrophils do not represent homogeneous population but perform multiple functions through confined subsets. Hence, in the present review we summarize various studies describing the heterogeneous nature of neutrophils and associated functions during steady state and pathological conditions.

Methodology
We performed extensive literature review with key words ‘Neutrophil subpopulations’ ‘Neutrophil subsets’, Neutrophil and infections’, ‘Neutrophil and metabolic disorders’, ‘Neutrophil heterogeneity’ in PUBMED.

Results
Neutrophil subtypes are characterized based on buoyancy, cell surface markers, localization and maturity. Recent advances in high throughput technologies indicate the existence of functionally diverse subsets of neutrophils in bone marrow, blood and tissues in both steady state and pathological conditions. Further, we found proportions of these subsets significantly vary in pathological conditions. Interestingly, stimulus specific activation of signalling pathways in neutrophils have been demonstrated.

Conclusion
Neutrophil sub-populations differ among diseases and hence, mechanisms regulating formation, sustenance, proportions and functions of these sub-types vary between physiological and pathological conditions. Hence, mechanistic insights of neutrophil subsets in disease specific manner may facilitate development of neutrophil-targeted therapies.
A review of excluded groups and non-response in population-based mental health surveys from high-income countries
Authors: Wright Eryn , Pagliaro Claudia , Page Imogen S. , Diminic Sandra 
Published: May 2023

Abstract
National mental health surveys play a critical role in determining the prevalence of mental disorders in a population and informing service planning. However, current surveys have important limitations, including the exclusion of key vulnerable groups and increasing rates of non-response. This review aims to synthesise information on excluded and undersampled groups in national mental health surveys. We conducted a targeted review of nationally representative adult mental health surveys performed between 2005 and 2019 in high-income OECD countries. Sixteen surveys met our inclusion criteria. The response rate for included surveys ranged between 36.3% and 80.0%. The most frequently excluded groups included people who were homeless, people in hospitals or health facilities and people in correctional facilities. Males and young people were the most commonly underrepresented groups among respondents. Attempts to collect data from non-responders and excluded populations were limited, but suggest that mental health status differs among some of these cohorts. The exclusion of key vulnerable groups and high rates of non-response have important implications for interpreting and using the results of national mental health surveys. Targeted supplementary surveys of excluded or hard-to-reach populations, more inclusive sampling methodologies, and strategies aimed at improving response rates should be considered to strengthen the accuracy and usefulness of survey findings.
Anomaly detection and virtual reality visualisation in supercomputers
Authors: Mulero-Pérez David , Benavent-Lledó Manuel , Azorín-López Jorge , Marcos-Jorquera Diego , García-Rodríguez José 
Published: May 2023

AbstractAnomaly detection is the identification of events or observations that deviate from the expected behaviour of a given set of data. Its main application is the prediction of possible technical failures. In particular, anomaly detection on supercomputers is a difficult problem to solve due to the large scale of the systems and the large number of components. Most research works in this field employ machine learning methods and regression models in a supervised fashion, which implies the need for a large amount of labelled data to train such systems. This work proposes the use of autoencoder models, allowing the problem to be approached with semi-supervised learning techniques. Two different model training approaches are compared. The former is a model trained with data from all the nodes of a supercomputer. In the latter approach, observing significant differences between nodes, one model is trained for each node. The results are analysed by evaluating the positive and negative aspects of each approach. On the other hand, a replica of the Marconi 100 supercomputer is developed in a virtual reality environment that allows the data from each node to be visualised at the same time.
Laser beam remelting of stainless steel plate for cladding and comparison with conventional CMT process
Authors: Bunaziv Ivan , Ren Xiaobo , Hagen Anette Brocks , Hovig Even Wilberg , Jevremovic Ivana , Gulbrandsen-Dahl Sverre 
Published: May 2023

AbstractProgressing towards circular economy requires smarter and more efficient use of energy and resources. Laser beam can be efficient and flexible tool for melting different metals, commonly used in cladding and additive manufacturing (AM) with a wire and powder feedstock. As an alternative, feedstock in the form of plates and sheets can be used for cladding to achieve corrosion resistant surfaces. Compared to powder or wire, plates are easier to process, less costly to use, and may come as scrap metal. This leads to smarter and more efficient resource utilization. However, processing plates in such way is not mature and requires more in-depth investigation to be competitive with well-established methods. In this work, 2.0 mm thick 316L stainless steel plates were remelted by a high-power fibre laser beam for cladding on carbon steel substrates. It was compared to the conventional cold metal transfer (CMT) welding-based arc cladding which is frequently used due to a low heat input. In the first phase, different defocusing distances were studied to understand the laser remelting process capabilities to optimize the productivity. It was found that a highly defocused laser beam provided unstable melt pool conditions with low track quality. Compared to CMT, the laser remelting provided enhanced productivity, reduced heat input by 50% per pass, and lower distortions. Microhardness testing showed an increase in hardness in the intermediate layer towards the fusion line due to carbon diffusion. Despite a higher delta ferrite formation in laser-remelted tracks, a comparable corrosion protection to CMT was observed. The proposed method is promising for reducing CO2 emissions with respect to reusing scrap metal in the form of plates or use of ordinary plates instead of filler wires which opens possibilities for further enhancements.
Colorectal Surgery in Patients with Liver Cirrhosis: A Systematic Review
Authors: Ng Zi Qin , Tan Patrick , Theophilus Mary 
Published: May 2023

AbstractBackgroundColorectal surgery in patients with liver cirrhosis poses a significant challenge due to the associated peri‐operative morbidity and mortality risks. The aim of this systematic review was to evaluate the outcomes in this cohort of patients following colorectal surgery.MethodsThe PubMed, Embase and Cochrane databases and references were searched up to October 2022 using the PRISMA guidelines. The data collated included: patient demographics, pathology or type of colorectal operation performed, severity of liver cirrhosis, post‐operative complication rates, mortality rates and prognostic factors. A quality assessment of included studies was performed with the Newcastle–Ottawa scale.ResultsSixteen studies reporting the outcomes of colorectal surgery in patients with liver cirrhosis were identified, including the results of 8646 patients. The indications, pathologies and/or type of operations varied. The overall complication rate ranged from 29 to 75%, minor complication ranged 14.5–37% and major complication ranged 6.7–59.3%. The mortality rates ranged from 0 to 37%.ConclusionColorectal surgery in patients with liver cirrhosis still carries considerable morbidity and mortality rates. This group of patients needs to be managed in a multidisciplinary setting to achieve excellent outcomes. Future research should focus on uniform definitions to enable interpretable outcomes.
The surgical anatomy of the axillary approach for nerve transfer procedures targeting the axillary nerve
Authors: Beytell Levo , Mennen Erich , van Schoor Albert-Neels , Keough Natalie 
Published: May 2023

Abstract
Purpose

The exact relational anatomy for the anterior axillary approach, targeting the axillary nerve for nerve transfers/grafts, has not been fully investigated. Therefore, this study aimed to dissect and document the gross anatomy surrounding this approach, specifically regarding the axillary nerve and its branches.

Methods
Fifty-one formalin-fixed cadavers (98 axilla) were bilaterally dissected simulating the axillary approach. Measurements were taken to quantify distances between identifiable anatomical landmarks and relevant neurovascular structures encountered during this approach. The musculo-arterial triangle, described by Bertelli et al., to aid in identification on localization of the axillary nerve, was also assessed.

Results
From the origin of the axillary nerve till (1) latissimus dorsi was 62.3 ± 10.7 mm and till (2) its division into anterior and posterior branches was 38.8 ± 9.6 mm. The origin of the teres minor branch along the posterior division of the axillary nerve was recorded as 6.4 ± 2.9 mm in females and 7.4 ± 2.8 mm in males. The musculo-arterial triangle reliably identified the axillary nerve in only 60.2% of the sample.

Conclusion
The results clearly demonstrate that the axillary nerve and its divisions can be easily identified with this approach. The proximal axillary nerve, however, was situated deep and therefore challenging to expose. The musculo-arterial triangle was relatively successful in localising the axillary nerve, however, more consistent landmarks such as the latissimus dorsi, subscapularis, and quadrangular space have been suggested. The axillary approach may serve as a reliable and safe method to reach the axillary nerve and its divisions, allowing for adequate exposure when considering a nerve transfer or graft.
Estimating prognostic relevant cutoff values for a multiplex PCR detecting BCR::ABL1 in chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy in resource-limited settings
Authors: Hailu Saifu , Kinde Samuel , Cross Michael , Tsegaye Aster , Kelemu Tsehayneh , Seifu Daniel , Alemayehu Dawit , Tarekegn Azeb , Jabessa Gutema , Abeje Desalegn , Abebe Markos , Sherif Abdulaziz , Tadesse Fisihatsion , Platzbecker Uwe , Howe Rawleigh , Gebremedhin Amha 
Published: May 2023

AbstractThe prognosis of chronic myeloid leukemia (CML) on tyrosine kinase inhibitor (TKI) treatment is based on the quantification of BCR::ABL1 fusion gene transcript copy number, harmonized by an international scale (IS) based on TaqMan-based real-time quantitative PCR (qRT-PCR). In Ethiopia, as in most low- and middle-income countries (LMICs), access to standard diagnostic, follow-up, and prognostic tools is very limited, and it has been challenging to strictly follow international guidelines. This seriously compromises clinical outcome, despite the availability of TKIs through the Glivec International Patient Assistance Program (GIPAP). Multiplex PCR (mpx-PCR), conventionally regarded as a “screening tool,” offers a potential solution to this problem. A total of 219 samples from confirmed CML patients were assayed. In reference to qRT-PCR, the AUC of ROC curve for mpx-PCR was 0.983 (95% CI: 0.957 to 0.997). At the optimum cut-off value, equivalent to BCR::ABL1 (IS) transcript copy number of 0.6%, the specificity and sensitivity were 93% and 95%, respectively, with 94% accuracy. Albeit the sensitivity and accuracy of mpx-PCR decrease below the optimum cutoff of 0.6% (IS), the specificity at 0.1% (IS) was 100%, making it an attractive means to rule-out relapse and drug non-adherence at later stages of treatment, which is particularly an issue in a low income setting. We conclude that the relative simplicity and low cost of mpx-PCR and prognostic relevant cutoff values (0.1–0.6% IS) should allow its use in peripheral clinics and thus maximize the positive impact of TKIs made available through GIPAP in most LMICs.