bluuebunny/crossref_metadata_2025_split huggingface dataset:
Landscape forming factors of the Karkaraly low mountains
Authors: Keukenov Ye. , Dzhanaleeva К. , Baryshnikov G. , Orazymbetova К. 
Published: August 2023

The territory of geosystems of the Karkaraly low mountains is mainly forest landscapes and dark-chestnut soil cover. The paper reflects the state of the soil and vegetation cover of the forest landscapes of the Karkaraly low mountains in the Karaganda region. The paper provides the results of chemical soil tests, describes the vegetation cover samples using geoinformation technologies based on the standard quantitative index NDVI (Normalized Difference Vegetation Index), confirmed in field studies in the summer of 2020. The work performed aims at a comprehensive assessment of the physical, chemical, and biological characteristics of the components of geosystems.
In course of the field study, a brief description of phytodiversity was compiled, indicating the geomorphological attributes of key areas. To study the vegetation, sample plots of the underlying soil and vegetation cover were set. Overview and thematic maps of the object under study were created. At the final stage of the study, the interpretation of the results is presented with the identification of cause-and-effect relationships of the state and fluctuations of geoecosystems. Data sources include satellite images of Landsat-8 (US Geological Survey) and field studies along the routes and four key areas. The results of the work allow defining the object under study, determining the distinctive properties in key areas, as well as possible reasons for the difference in the studied territory of geosystems.
PEMBENTUKAN PERPADUAN DI MALAYSIA MELALUI NILAI BUDAYA DALAM ANIMASI UPIN DAN IPIN (Unity Formation in Malaysia Through Cultural Values in Upin and Ipin Animation)
Authors: Md Ariff Siti Nurkhalida , Deng Phat a/l Awang , Yaakub Yusniza 
Published: August 2023

ABSTRAK
Tidak dapat dinafikan lagi bahawa perpaduan kaum di Malaysia belum lagi utuh. Perasaan curiga antara kaum masih lagi wujud kerana sesetengah masyarakat yang terpengaruh dengan sentimen perkauman yang sering dihujahkan oleh pihak-pihak tertentu termasuklah ahli politik. Hal ini telah menyebabkan masyarakat di Malaysia kurang memahami budaya masyarakat lain malah takut untuk bergaul dengan kaum lain. Kepelbagaian budaya di Malaysia perlu diraikan oleh setiap masyarakat di Malaysia dengan berusaha untuk memahami budaya kaum lain. Animasi Upin dan Ipin memainkan peranan dalam mempromosikan budaya majmuk di Malaysia dengan memaparkan perasaan kasih sayang dan keharmonian rakyat Malaysia, malah telah diangkat sebagai duta mahabbah. Oleh itu, kajian ini bertujuan untuk mengenal pasti dan menganalisis nilai-nilai pendidikan budaya yang terdapat dalam animasi Upin dan Ipin yang dapat membantu dalam membentuk perpaduan di Malaysia terutamanya dalam kalangan kanak-kanak. Kajian berbentuk kualitatif ini menggunakan kaedah analisis kandungan sebagai reka bentuk kajian untuk menyerlahkan nilai pendidikan budaya dalam animasi Upin dan Ipin berdasarkan pandangan Teori Sosiolisasi. Hasil kajian mendapati bahawa nilai budaya yang terdapat dalam animasi Upin dan Ipin memberikan pengetahuan yang baharu tentang kepelbagaian budaya di Malaysia, serta penting sebagai satu usaha memupuk perpaduan di Malaysia.
ABSTRACT

It can’t be denied that racial unity in Malaysia is not perfectly intact. Feelings of prejudices among races still exist due to the influences of racial sentiments that often argued by certain parties including politicians. This has created lack of understanding among Malaysian regarding other culture and even afraid to mingle with other races. Cultural diversity needs to be celebrated by every community in Malaysia through understanding of the culture of every Malaysian. Upin and Ipin animations play a role in promoting pluralistic culture in Malaysia by displaying the feelings of love and harmony as Malaysians, and have even been appointed as ambassadors of love. Therefore, this study aims to identify and analyze the values of cultural values found in Upin and Ipin animation that can assist forming unity in Malaysia especially among children. This qualitative study uses the content analysis method as a research design to highlight the value of cultural values in Upin and Ipin animation based on the view of Socialization Theory. The results of the study found that the cultural values found in Upin and Ipin animation provide new knowledge about cultural diversity in Malaysia, as well as being important as an effort to gain unity in Malaysia.
НА ШЛЯХУ ФОРМУВАННЯ ЦИФРОВИХ АРХІВІВ (РЕПОЗИТОРІЇВ) МУЗИЧНОГО ФОЛЬКЛОРУ В УКРАЇНІ (РОЗРОБКА ІНФРАСТРУКТУРИ РОБОЧОГО СЕРЕДОВИЩА)
Authors: Kropyvnyi Oleksandr 
Published: August 2023

Збереження фольклорних колекцій, включаючи аудіовізуальні архіви польових матеріалів, є надзвичайно важливим завданням, особливо в умовах російської агресії в Україні. Безпека зберігання інформації стала одним з найгостріших викликів в умовах воєнного часу, коли музейні фонди опинилися під загрозою знищення, а доступ до них ускладнений. Українські архівісти усвідомлюють необхідність формування нових принципів зберігання даних, передусім оцифрування (дигіталізацію) колекцій українського музичного фольклору й створення сучасних пошукових структур для орієнтації в цих зібраннях. Проте спільна візія майбутнього таких сховищ-репозиторіїв ще не сформована. Від початку війни активізувалися дискусії про створення сучасного централізованого сховища для об’єктів українського музичного та словесного фольклору. Прихильники цього підходу намагаються вирішити спільні проблеми впорядкування фольклорних архівів різних українських наукових інституцій та приватних фондів окремих дослідників. Напрацювання ініціаторів централізованого підходу (головно – Андрія Вовчака) наразі стосуються логічної структури пропонованого сховища, тоді як першочергові практичні питання забезпечення технічної інфраструктури (зокрема, варіанти периферійного обладнання для обслуговування та наповнення сховища) залишаються не вирішеними. Мета статті – розглянути концепцію цифрового репозиторію українського музичного фольклору (ЦР УМФ), що не існує відособлено, а є складовою робочого середовища, призначеного для зберігання, наукового опрацювання, аналізу та розповсюдження аудіовізуальних об’єктів українського музичного фольклору. Методологія. Методологічну базу статті складають роботи українських та зарубіжних дослідників, які вивчали архівне зберігання фіксацій українського музичного фольклору, зокрема А. Вовчака [2-6], І. Клименко [8], К. Гончаренко [7] та ін. Теорію побудови технічної інфраструктури автор почерпнув з досліджень зарубіжних фахівців з області інформаційних технологій [12, 17], архівістів [16, 18], а також з технічної документації до програмних продуктів та апаратного забезпечення [13, 15]. Наукова новизна публікації полягає у висвітленні раніше недосліджених аспектів технічної реалізації цифрового репозиторію українського музичного фольклору. Висновки. У статті описано основні елементи фізичної (апаратної) інфраструктури цифрового репозиторію українського музичного фольклору та запропоновано нові підходи до організації централізованої роботи з фондами музичного фольклору шляхом застосування концепції робочих станцій. Окреслено технологічні шляхи реалізації фізичної інфраструктури пропонованого робочого середовища та цифрового репозиторію, з метою забезпечення масштабованості та надійності сховища.
PROBLEMATIKA PELAKSANAAN PEMBUKAAN UNDANG-UNDANG DASAR 1945 DALAM SEGI NILAI KEBANGSAAN PADA GENERASI Z DAN ALPHA
Authors: Hutapea Elsa Kristina , Santoso Puguh , FS Alexandra Halomoan 
Published: August 2023

Artikel ini bertujuan menguraikan problematika pelaksanaan Pembukaan Undang-Undang Dasar 1945 dengan titik sasaran menurunnya Nilai Kebangsaan pada generasi Z dan Alpha Indonesia di era Digital setelah pandemi Covid-19 dan menganalisis urgensi pelaksanaan Pembukaan Undang-Undang Dasar 1945 yang salah satunya mencerdaskan kehidupan bangsa sebagai salah satu upaya untuk menyelamatkan generasi Indonesia. Artikel ini disusun dengan mengunakan metode library review (tinjauan pustaka), dengan fokus pada generasi Indonesia. Peneliti mengumpulkan data dari berbagai sumber, seperti artikel jurnal, buku, dan sumber lain yang terkait. Hasil dari penelitian ini menunjukkan bahwa penurunan nilai kebangsaan mengalami eskalasi, terutama satelah terjadinya Covid-19, yang ditandai banyak generasi Indonesia yang tidak mengetahui nilai kebangsaan dan ini menimbulkan problematika akan pelaksanaan Pembukaan Undang-Undang Dasar 1945. Covid-19 merupakan pandemi yang mempengaruhi menurunnya kesadaran generasi Z dan Alpha disamping semua ini merupakan tanggung jawab bersama. Perhatian yang harus diberikan kepada generasi Z dan Alpha tidak hanya dibebankan pada lembaga pendidikan. Namun, ini juga tanggung jawab para orang tua, Pemerintah dan tokoh masyarakat. Selain itu, hasil lain menunjukkan bahwa jika tidak kita yang menyelamatkan generasi Z dan Alpha maka akan berdampak dikemudian hari bahwa penerus Bangsa Indonesia mengalami kemunduran karena tidak mengenal nilai Kebangsaannya sendiri bahkan tidak mengetahui jati diri sebagai Warga Negara Indonesia yang baik dalam memperjuangkan dan mencapai upaya mencerdaskan Bangsa.
Kata kunci: Covid-19, Generasi, Nilai Kebangsaan
Cuidados de enfermagem a pacientes com COVID-19 em Unidade de Terapia Intensiva: uma revisão integrativa
Authors: Silva Clara Mariana Vicente da , Silva Julio Cesar Pereira da , Santos Dandhara Anardys Costa dos , Vieira Dhamaris de Araujo , Marques Silvia Luana Lima , Nojosa Samira da Silva , Barbosa Luana Cristina de Souza 
Published: August 2023

Objetivo: Analisar, a partir da literatura, quais os cuidados de enfermagem a pacientes com COVID-19 em unidade de terapia intensiva. Metodologia: Trata-se de uma revisão integrativa de literatura, realizada mediante a busca de estudos em três bases de dados nacionais e internacionais: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Banco de Dados de Enfermagem (BDENF) e Medical Literature Analysis and Retrievel System Online (MEDLINE). A amostra final foi constituída por 15 estudos publicados. Resultados e Discussão: Após cruzamento dos descritores e aplicabilidade dos critérios de inclusão e exclusão a discussão foi realizada com base em 15 artigos. Conclusão: A enfermagem presta cuidados assistenciais desde aporte de oxigenoterapia, monitorização cardíaca, cuidados com a função renal, além de apoio emocional a partir do uso de tecnologias e da musicalização. Os desafios relativos à escassez de recursos matérias e humanos foi destacado, porém a enfermagem se sobressaiu com um cuidar flexível e inovador com vistas a práticas pautadas na sistematização e no processo de enfermagem.
DETERMINAN NILAI PERUSAHAAN TERHADAP SEKTOR CONSUMER NON CYCLICALS
Authors: Fauziyanti Wachidah , Sarbullah Sarbullah , F Lia Anisatul 
Published: August 2023

Nilai perusahaan merupakan kondisi tertentu yang telah dicapai oleh suatu perusahaan sebagai gambaran dari kepercayaan masyarakat terhadap perusahaan setelah melalui satu proses kegiatan selama beberapa tahun, Penelitian ini bertujuan untuk mengetahui pengaruh struktur modal, pertumbuhan perusahaan dan profitabilitas terhadap nilai perusahaan pada perusahaan sektor consumer non-cyclicals yang terdaftar di Bursa Efek Indonesia tahun 2019-2021. Populasi dalam penelitian ini adalah perusahaan sektor consumer non-cyclicals indeks papan utama yang terdaftar di Bursa Efek Indonesia berjumlah 57 perusahaan. Sampel dalam penelitian ini menggunakan purposive sampling sehingga diperoleh sampel sebanyak 30 perusahaan. Metode analisis data menggunakan analisis regresi linier berganda.
Berdasarkan hasil analisis data disimpulkan bahwa Struktur modal berpengaruh signifikan terhadap nilai perusahaan, pertumbuhan perusahaan tidak berpengaruh signifikan terhadap nilai perusahaan, Profitabilitas tidak berpengaruh signifikan terhadap nilai perusahaan. Saran dan kesimpulan untuk peneliti selanjutnya disarankan untuk menguji faktor-faktor lain yang diduga dapat mempengaruhi terjadinya nilai perusahaan
PENERAPAN PENERAPAN LAPORAN KEUANGAN BERDASARKAN STANDAR AKUNTANSI KEUANGAN ENTITAS MIKRO, KECIL DAN MENENGAH (SAK EMKM)
Authors: Fandil Fandil , Sarbullah Sarbullah 
Published: August 2023

Abstraksi.
Permasalahan yang umumnya dialami para pelaku UMKM adalah keterbatasan pemahaman akuntansi yang memiliki kemampuan dalam akuntansi. Hal ini menyebabkan UMKM menggunakan pencatatan sederhana yaitu dengan mencatat penerimaan dan pengeluaran kas. Tujuan penelitian ini yaitu untuk menganalisis penerapan laporan keuangan berdasarkan Standar Akuntansi Keuangan Entitas Mikro, Kecil dan Menengah (SEK-EMKM) Pada UMKM UD. Andalan jaya. Jenis penelitian menggunakan penelitian kualitatif. Desain penelitian menggunakan metode deskriptif kualitatif. Penelitian ini dilakukan pada UMKM UD. Andalan Jaya di Kabupaten Tegal. Jenis data yang digunakan data primer. Data primer dari penelitian ini berasal dari jawaban responden seperti jawaban atas interview pelaku usaha. Data diperoleh dengan melakukan wawancara, observasi dan dokumentasi langsung. Data tersebut dianalisis menggunakan akuntansi pokok dalam penyusunan laporan keuangan pada UD Andalan Jaya berdasarkan literatur Standar Akuntansi Keuangan Entitas Mikro, Kecil dan Menengah (SAK EMKM) tahun 2018. Hasil penelitian bahwa UD Andalan Jaya tidak memiliki laporan keuangan dan hanya memiliki catatan atas transaksi penjualan dan pembelian, sehingga hal ini tidak sesuai dengan pedoman Standar Akuntansi Keuangan Entitas Mikro Kecil dan Menengah. Penelitian ini menghasilkan posisi keuangan UD Andalan Jaya periode 31 Desember 2020 sebagai berikut Aset Rp. 1.795.099.224, Kewajiban Rp. 750.000.000, Modal Rp. 1.045.099.224, dan Laba bersih Rp. 240.099.224.
Capra cartilage-derived peptide delivery via carbon nano-dots for cartilage regeneration
Authors: Maity Priti Prasanna , Kapat Kausik , Poddar Puja , Bora Hema , Das Chandan Kanta , Das Poushali , Ganguly Sayan , Das Narayan Chandra , Dhara Dibakar , Mandal Mahitosh , Roy Chowdhury Amit , Mukherjee Sumanta , Dhara Santanu 
Published: August 2023

Targeted delivery of site-specific therapeutic agents is an effective strategy for osteoarthritis treatment. The lack of blood vessels in cartilage makes it difficult to deliver therapeutic agents like peptides to the defect area. Therefore, nucleus-targeting zwitterionic carbon nano-dots (CDs) have immense potential as a delivery vehicle for effective peptide delivery to the cytoplasm as well as nucleus. In the present study, nucleus-targeting zwitterionic CDs have been synthesized as delivery vehicle for peptides while also working as nano-agents towards optical monitoring of cartilage healing. The functional groups of zwitterion CDs were introduced by a single-step microwave assisted oxidation procedure followed by COL II peptide conjugation derived from Capra auricular cartilage through NHS/EDC coupling. The peptide-conjugated CDs (PCDs) allows cytoplasmic uptake within a short period of time (∼30 m) followed by translocation to nucleus after ∼24 h. Moreover, multicolor fluorescence of PCDs improves (blue, green, and read channel) its sensitivity as an optical code providing a compelling solution towards enhanced non-invasive tracking system with multifunctional properties. The PCDs-based delivery system developed in this study has exhibited superior ability to induce ex-vivo chondrogenic differentiation of ADMSCs as compared to bare CDs. For assessment of cartilage regeneration potential, pluronic F-127 based PCDs hydrogel was injected to rabbit auricular cartilage defects and potential healing was observed after 60 days. Therefore, the results confirm that PCDs could be an ideal alternate for multimodal therapeutic agents.
Bridging the extracellular vesicle knowledge gap: insights from non-mammalian vertebrates, invertebrates, and early-diverging metazoans
Authors: Liegertová Michaela , Janoušková Olga 
Published: August 2023

Extracellular vesicles (EVs) are lipid-enclosed structures that facilitate intercellular communication by transferring cargo between cells. Although predominantly studied in mammals, extracellular vesicles are ubiquitous across metazoans, and thus research in non-mammalian models is critical for fully elucidating extracellular vesicles biology. Recent advances demonstrate that extracellular vesicles mediate diverse physiological processes in non-mammalian vertebrates, including fish, amphibians, and reptiles. Piscine extracellular vesicles promote fin regeneration in zebrafish and carry heat shock proteins regulated by stress. Frog extracellular vesicles containing microRNAs modulate angiogenesis, while turtle extracellular vesicles coordinate reproductive functions. Venom from snakes contains extracellular vesicles that mirror the whole venom composition and interact with mammalian cells. Invertebrates also possess extracellular vesicles involved in immunity, development, and pathogenesis. Molluscan extracellular vesicles participate in shell formation and host interactions. Arthropod models, including Drosophila, genetically dissect conserved pathways controlling extracellular vesicles biogenesis and signalling. Nematode extracellular vesicles regulate larval development, animal communication, and ageing via conserved extracellular vesicles proteins. Ancient metazoan lineages utilise extracellular vesicles as well, with cnidarian extracellular vesicles regulating immunity and regeneration. Ultimately, expanding extracellular vesicles research beyond typical biomedical models to encompass phylogenetic diversity provides an unparalleled perspective on the conserved versus specialised aspects of metazoan extracellular vesicles roles over ∼500 million years. With a primary focus on the literature from the past 5 years, this review aims to reveal fundamental insights into EV-mediated intercellular communication mechanisms shaping animal physiology.
Changes of ubiquitylated proteins in atrial fibrillation associated with heart valve disease: proteomics in human left atrial appendage tissue
Authors: Wu Chen-Kai , Teng Shuai , Bai Fan , Liao Xiao-Bo , Zhou Xin-Min , Liu Qi-Ming , Xiao Yi-Chao , Zhou Sheng-Hua 
Published: August 2023

BackgroundCorrelations between posttranslational modifications and atrial fibrillation (AF) have been demonstrated in recent studies. However, it is still unclear whether and how ubiquitylated proteins relate to AF in the left atrial appendage of patients with AF and valvular heart disease.MethodsThrough LC–MS/MS analyses, we performed a study on tissues from eighteen subjects (9 with sinus rhythm and 9 with AF) who underwent cardiac valvular surgery. Specifically, we explored the ubiquitination profiles of left atrial appendage samples.ResultsIn summary, after the quantification ratios for the upregulated and downregulated ubiquitination cutoff values were set at &gt;1.5 and &lt;1:1.5, respectively, a total of 271 sites in 162 proteins exhibiting upregulated ubiquitination and 467 sites in 156 proteins exhibiting downregulated ubiquitination were identified. The ubiquitylated proteins in the AF samples were enriched in proteins associated with ribosomes, hypertrophic cardiomyopathy (HCM), glycolysis, and endocytosis.ConclusionsOur findings can be used to clarify differences in the ubiquitination levels of ribosome-related and HCM-related proteins, especially titin (TTN) and myosin heavy chain 6 (MYH6), in patients with AF, and therefore, regulating ubiquitination may be a feasible strategy for AF.
Robust intra-model teleconnection patterns for extreme heatwaves
Authors: Miloshevich George , Rouby-Poizat Philippine , Ragone Francesco , Bouchet Freddy 
Published: August 2023

Introduction: The goal of this study is to provide analysis of statistics and dynamics of extreme heatwaves over two areas of Europe, France and Scandinavia, while comparing and contrasting the representation in climate models and reanalysis.Methods: The 1000 year long datasets are generated using respectively two climate models of different complexity. The composite maps of the heatwaves found in these datasets are compared to the ones observed in reanalysis by estimating significance of such patterns. We also employ time series analysis, in particular compare return time plots and use Gaussian stochastic processes to model the temporal correlations for rare events.Results: Our investigation reveals that recurrent wavenumber three teleconnection patterns distinctly underpin heatwaves in France and Scandinavia. These patterns manifest in both surface temperature and mid-tropospheric geopotential height. For heatwaves of return times of 4 years such patterns are robustly represented across diverse models of complexity and reanalysis data. For longer return times, reanalysis records are too short to give statistically significant results, while models confirm the relevance of these large scale patterns for the most extreme heatwaves. Moreover, A time series analysis shows that heatwave indices defined at synoptic scale are fairly well described by Gaussian stochastic processes, and that these Gaussian processes reproduce well return time plots even for very rare events.Discussion: These results suggest that extreme heatwaves over different areas of Europe show recurrent typical behaviours in terms of long-range spatial correlations and subseasonal-scale temporal correlations. These properties are consistently represented among models of different complexity and observations, thus suggesting their relevance for a better understanding of the drivers and causes of the occurrence of extreme midlatitude heatwaves and their predictability.
Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters?
Authors: Martin Joseph V. , Sarkar Pradip K. 
Published: August 2023

We review the evidence regarding the nongenomic (or non-canonical) actions of thyroid hormones (thyronines) and their derivatives (including thyronamines and thyroacetic acids) in the adult brain. The paper seeks to evaluate these compounds for consideration as candidate neurotransmitters. Neurotransmitters are defined by their (a) presence in the neural tissue, (b) release from neural tissue or cell, (c) binding to high-affinity and saturable recognition sites, (d) triggering of a specific effector mechanism and (e) inactivation mechanism. Thyronines and thyronamines are concentrated in brain tissue and show distinctive patterns of distribution within the brain. Nerve terminals accumulate a large amount of thyroid hormones in mature brain, suggesting a synaptic function. However, surprisingly little is known about the potential release of thyroid hormones at synapses. There are specific binding sites for thyroid hormones in nerve-terminal fractions (synaptosomes). A notable cell-membrane binding site for thyroid hormones is integrin αvβ3. Furthermore, thyronines bind specifically to other defined neurotransmitter receptors, including GABAergic, catecholaminergic, glutamatergic, serotonergic and cholinergic systems. Here, the thyronines tend to bind to sites other than the primary sites and have allosteric effects. Thyronamines also bind to specific membrane receptors, including the trace amine associated receptors (TAARs), especially TAAR1. The thyronines and thyronamines activate specific effector mechanisms that are short in latency and often occur in subcellular fractions lacking nuclei, suggesting nongenomic actions. Some of the effector mechanisms for thyronines include effects on protein phosphorylation, Na+/K+ ATPase, and behavioral measures such as sleep regulation and measures of memory retention. Thyronamines promptly regulate body temperature. Lastly, there are numerous inactivation mechanisms for the hormones, including decarboxylation, deiodination, oxidative deamination, glucuronidation, sulfation and acetylation. Therefore, at the current state of the research field, thyroid hormones and their derivatives satisfy most, but not all, of the criteria for definition as neurotransmitters.