bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intratendinous pressure of the Achilles tendon during exercise is related to the degree of tendon torsion
Authors: Pringels Lauren , Stouthandel Michael , Van Hoof Tom , Martens Manuel , Chevalier Amelie , Burssens Arne , Wezenbeek Evi , Vanden Bossche Luc 
Published: August 2023

AbstractTorsion of the Achilles tendon (AT) enhances tensile strength, but a high degree of torsion might also be a risk factor for Achilles tendinopathy, due to greater internal compression exerted during tensile loading. However, evidence supporting the grounds for this assumption is lacking. Hence, we aimed to investigate the impact of AT torsion type on intratendinous pressure. Eighteen human fresh frozen cadaveric legs were mounted in a testing rig and a miniature pressure catheter was placed through ultrasound‐guided insertion in the midportion region of the AT. Intratendinous pressure was measured during a simulated straight‐knee calf stretch and eccentric heel drop. The AT was then carefully dissected and classified into Type I (least), Type II (moderate), and Type III (extreme) torsion. Of the ATs examined, nine were found to have Type I torsion (50%), nine Type II (50%), and none Type III. It was found that the intratendinous pressure of the AT increased exponentially with ankle dorsiflexion during both exercises (p < 0.001) and that this increase was greater in ATs with Type II torsion than Type I torsion (p < 0.05). This study provides the first biomechanical data to support the hypothesis that in athletes with a high degree of torsion in the AT, the midportion area will experience more internal compression during exercise, for example, calf stretching and eccentric heel drops. Whether this phenomenon is also associated with an elevated risk for Achilles tendinopathy needs further prospective investigation.
Aerobic high‐intensity intervals improve V̇O2max more than supramaximal sprint intervals in females, similar to males
Authors: Helgerud Jan , Hov Håkon , Mehus Håkon , Balto Bård , Boye Anders , Finsås Lars , Hoff Jan , Wang Eivind 
Published: August 2023

AbstractIntroductionMaximal oxygen uptake (V̇O2max) is a pivotal factor for aerobic endurance performance. Recently, aerobic high‐intensity interval training (HIIT) was documented to be superior to sprint interval training (SIT) in improving V̇O2max in well‐trained males. However, as mounting evidence suggests that physiological responses to training are sex‐dependent, examining the effects of HIIT versus SIT on V̇O2max, anaerobic capacity, and endurance performance in females is warranted.MethodsWe randomized 81 aerobically well‐trained females (22 ± 2 years, 51.8 ± 3.6 mL∙kg−1∙min−1 V̇O2max), training three times weekly for 8 weeks, to well‐established protocols: (1) HIIT 4 × 4 min at ~95% of maximal aerobic speed (MAS), with 3 min active recovery (2) SIT 8 × 20 s at ~150% of MAS, with 10 s passive recovery (3) SIT 10 × 30 s at ~175% of MAS, with 3.5 min active recovery.ResultsOnly HIIT 4 × 4 min increased V̇O2max (7.3 ± 3.1%), different from both SIT groups (all p < 0.001). Anaerobic capacity (maximal accumulated oxygen deficit) increased following SIT 8 × 20 s (6.5 ± 10.5%, p < 0.05), SIT 10 × 30 s (14.4 ± 13.7%, p < 0.05; different from HIIT 4 × 4 min, p < 0.05). SIT 10 × 30 s resulted in eight training‐induced injuries, different from no injuries following HIIT 4 × 4 min and SIT 8 × 20 s (p < 0.001). All groups improved long‐distance (3000‐meter) and sprint (300‐meter) running performance (all p < 0.001). SIT protocols improved sprint performance more than HIIT 4 × 4 min (p < 0.05). Compared to previous male results, no increase in V̇O2max following SIT 8 × 20 s (p < 0.01), and a higher injury rate for SIT 10 × 30 s (p < 0.001), were evident.ConclusionsIn aerobically well‐trained women, HIIT is superior to SIT in increasing V̇O2max while all‐out treadmill running SIT is potentially more harmful.
Queering reproductive justice: Framing reproduction of gay men from a transnational perspective—Taiwan as a case
Authors: Chen Jung 
Published: August 2023

AbstractThis article uses Taiwan as an example to argue that reproductive justice for gay men should be conceptualised within social, legal, and political contexts. Taiwan is the first Asian country to legalise same‐sex marriage, yet the law favours heterosexual couples and denies LGBTQ+ reproductive rights. Thus, Taiwanese gay men seek third‐party reproduction overseas to become parents. This article exemplifies gay men's unequal conditions from a non‐Western perspective. I re‐examine scholarly literature on the interlocking concepts of reproductive justice, stratified reproduction, and queer reproduction to answer what reproductive justice gay men need and how their injustice position situates within and beyond the nation‐state borders. Drawing on the reproductive justice framework and studies of queer reproduction, this article proposes a transnational perspective to understand queer reproductive justice through the case that elucidates the specific context of Taiwanese gay men. This article aims to make two contributions. Firstly, it reconsiders the reproductive framework from a transnational perspective to argue that gay men's reproductive justice should be conceptualised at the intersection with other dimensions of injustice. Secondly, this article suggests that the transnational approach could be applied as a critical lens for future research in queer reproduction and reproductive justice.
Management of perioperative iron deficiency anemia as part of patient blood management in France: A budget impact model‐based analysis based on real world data
Authors: Lasocki Sigismond , Delahaye D. , Fuks D. , Savoie P. H. , Dussart C. , Hofmann A. , Paubel P. 
Published: August 2023

AbstractObjectivesPatient Blood Management (PBM) is defined as a patient‐centered, systematic, evidence‐based approach to improve patient outcomes by managing and preserving a patient's own blood, while promoting patient safety and empowerment. As a corollary, it also reduces the utilization of allogeneic blood components. However, demonstrating cost‐effectiveness depends on the health insurance system considered. This analysis aims to estimate the one‐year budget impact of PBM in four elective surgical areas, from French National Health Insurance and hospital perspectives.MethodsA budget impact model was developed to estimate the difference in the cost of care between scenarios with and without PBM. The impact of hematopoiesis optimization (first pillar of PBM) was studied throughout the management of preoperative anemia and iron deficiency in four types of surgeries: orthopedic, cardiac & cardiovascular, vascular & thoracic, and urologic & visceral surgery. Estimation of model's parameters was based on data collected in 10 French hospitals, literature, and on data from the French national medico‐administrative database.ResultsA total of 980,125 patients were modeled for all four therapeutic areas. Results shows that implementation of a PBM program could generate annual savings up to €1079 M from the French National Health Insurance perspective (€1018 M from the hospital perspective), and the sparing of 181,451 red blood cells units per year. The deterministic sensitivity analysis showed that PBM generates savings for both perspectives in most parameters tested.ConclusionImplementing PBM programs could result in important savings for the health care system in France.
Simplicial approach to path homology of quivers, marked categories, groups and algebras
Authors: Ivanov Sergei O. , Pavutnitskiy Fedor 
Published: August 2023

AbstractWe develop a generalisation of the path homology theory introduced by Grigor'yan, Lin, Muranov and Yau (GLMY theory) in a general simplicial setting. The new theory includes as particular cases the GLMY theory for path complexes and new homology theories: path homology of categories with a chosen set of morphisms (marked categories) groups with a chosen subset (marked groups) and path Hochschild homology of algebras with chosen vector subspaces (marked algebras). Using our general machinery, we also introduce a new homology theory for quivers that we call square‐commutative homology of quivers and compare it with the theory developed by Grigor'yan, Muranov, Vershinin and Yau.
Single and Double Cantilever Beam Large Displacement Mixed Mode Fracture Toughness Test Methods and J-Integral Analyses
Authors: Paris Anthony J. 
Published: August 2023

Abstract
The J-integral is applied to the single cantilever beam (SCB) and double cantilever beam (DCB) test specimens subjected to both mixed-mode I and II loading and large displacements. The methods proposed and resulting closed-form theoretical equations allow for the instantaneous evaluation of J during laboratory tests, requiring only the applied load and angular rotation of the specimen loading link, loading points, and remaining ligament. These measurands can be acquired using a common load cell and markers, a digital video camera, and image analysis software. In general, the equations do require knowledge of the specimen elastic moduli and shear moduli, as well as the specimen linear dimensions. Since the test data can be analyzed and J determined throughout the test instantaneously, and since, due to geometric nonlinearities, the ratio of mode I and mode II loading will likely vary significantly throughout the test, each specimen can be used to generate multiple data points. If crack length is determined throughout the test, presumably by directly measuring the crack length optically, or if the load drops abruptly due to crack growth, then when the crack advances, critical values of J for mixed-mode loading can be determined using the methods and results presented. It is noted that moderate to large translational and rotational displacements may improve the accuracy of the results using these methods. The results are applicable to standard pure mode I or pure mode II SCB and DCB tests as well and reduce to known equations in those special cases.
HG-CAD: Hierarchical Graph Learning for Material Prediction and Recommendation in Computer-Aided Design
Authors: Bian Shijie , Grandi Daniele , Liu Tianyang , Jayaraman Pradeep Kumar , Willis Karl , Sadler Elliot , Borijin Bodia , Lu Thomas , Otis Richard , Ho Nhut , Li Bingbing 
Published: August 2023

Abstract
To support intelligent computer-aided design (CAD), we introduce a machine learning architecture, namely HG-CAD, that recommends assembly body material through joint learning of body- and assembly-level features using a hierarchical graph representation. Specifically, we formulate the material prediction and recommendation process as a node-level classification task over a novel hierarchical graph representation of CAD models, with a low-level graph capturing the body geometry, a high-level graph representing the assembly topology, and a batch-level mask randomization enabling contextual awareness. This enables our network to aggregate geometric and topological features from both the body and assembly levels, leading to competitive performance. Qualitative and quantitative evaluation of the proposed architecture on the Fusion 360 Gallery Assembly Dataset demonstrates the feasibility of our approach, outperforming selected computer vision and human baselines while showing promise in application scenarios. The proposed HG-CAD architecture that unifies the processing, encoding, and joint learning of multi-modal CAD features indicates the potential to serve as a recommendation system for design automation and a baseline for future work.
Exploring the Effects of Perceived Complexity Criteria on Performance Measures of Human–Robot Collaborative Assembly
Authors: Verna Elisa , Puttero Stefano , Genta Gianfranco , Galetto Maurizio 
Published: August 2023

AbstractThe use of Human–Robot Collaboration (HRC) in assembly tasks has gained increasing attention in recent years as it allows for the combination of the flexibility and dexterity of human operators with the repeatability of robots, thus meeting the demands of the current market. However, the performance of these collaborative systems is known to be influenced by various factors, including the complexity perceived by operators. This study aimed to investigate the effects of perceived complexity on the performance measures of HRC assembly. An experimental campaign was conducted in which a sample of skilled operators was instructed to perform six different variants of electronic boards and express a complexity assessment based on a set of assembly complexity criteria. Performance measures such as assembly time, in-process defects, quality control times, offline defects, total defects, and human stress response were monitored. The results of the study showed that the perceived complexity had a significant effect on assembly time, in-process and total defects, and human stress response, while no significant effect was found for offline defects and quality control times. Specifically, product variants perceived as more complex resulted in lower performance measures compared to products perceived as less complex. These findings hold important implications for the design and implementation of HRC assembly systems and suggest that perceived complexity should be taken into consideration to increase HRC performance.
Li-Ion Battery Electrode Manufacturing Control System in Winding Process: Tension Control in Industrial Complex Roll-to-Roll Winding Machine Via SMC-FLC Hybrid Control Method
Authors: Chen Haozhen , Ni Jun 
Published: August 2023

Abstract
This paper introduces a new control method for web tension control on a complex roll-to-roll winding machine used in battery production. A traditional web tension control method cannot perform well enough under high winding speed: the parameter tuning process is time-consuming, the disturbance rejection performance is not satisfying, and the control performance is not stable. A hybrid control method is proposed, and it is easy to be implemented on common programming platform for commercial winding machines with an easy tuning process, while providing superior control performance to the traditional control method. The system modeling used in the control method is much simpler than the modeling in most of the tension control researches, providing better feasibility for industrial application.
Historically Black College and University Faculty’s Perception of Commission on Sport Management Accreditation and Perceived Barriers
Authors: Stowe Rennae Williams , Crowley Charles 
Published: August 2023

Program-level accreditation ensures that students will be equipped with the knowledge and skills needed to be successful in a career that is based on industry standards. Numerous researchers have reported the cost and benefits of pursuing specialized accreditation in different disciplines. There is a dearth of research related to specialized accreditation at historically Black colleges and universities (HBCUs) in general and none specifically for sport management accreditation. Therefore, this study aims to fill the void of research on the perception of the Commission on Sport Management Accreditation (COSMA) by faculty and administrators at HBCUs. The researchers were given permission to utilize an existing survey. Results of this study found that the top benefits of accreditation were accountability for program improvements and recognition as a superior (elite) program/institution. Cost and redundancy were reported as major barriers to COSMA. Although HBCUs must deal with fewer resources and a lower budget than most predominantly White institutions (PWI), they are evaluated using the same accreditation standards as PWIs. Therefore, if HBCU sport management programs are going to seek accreditation with COSMA, they must be understood within the context in which they are operating—and how that may be different from PWIs.
In vitro
efficacy of humanized regimen of flomoxef against extended-spectrum β-lactamase-producing
Escherichia coli
and
Klebsiella pneumoniae
Authors: Yamashiro Hidenori , Kasamatsu Yu , Anan Naomi , Takemura Miki , Yamano Yoshinori 
Published: August 2023

ABSTRACT

This study compared the efficacy of flomoxef with other β-lactam antibiotics against extended-spectrum β-lactamases (ESBL)-producing bacteria of clinical relevance. First, the prevalence and β-lactamase genotypes of ESBL-producing strains among
Escherichia coli
and
Klebsiella pneumoniae
isolates collected in Japan from 2004 to 2018 were investigated. High MIC
90
values (>64 µg/mL) of ceftriaxone, cefepime, and ceftazidime and low MIC
90
values (≤0.06–2 µg/mL) of flomoxef, cefmetazole, and meropenem against both species were observed. Second, a chemostat model was used to analyze the efficacy of humanized regimens of three oxacephem/cephamycin antibiotics (flomoxef, cefmetazole, cefoxitin) and two other antibiotics (meropenem and piperacillin/tazobactam) in suppressing the growth of five ESBL-producing
E. coli
and two
K. pneumoniae
strains. Flomoxef, piperacillin/tazobactam, and meropenem showed good bactericidal effects with >4 log
10
CFU/mL reduction without bacterial regrowth at 24 h even when the MIC of test isolates was >MIC
90
. Cefmetazole and cefoxitin resulted in regrowth of test isolates with MIC ≥MIC
90
at 24 h. Cefmetazole, cefoxitin, flomoxef, and meropenem showed increased MICs for regrown samples. A clear relationship between the proportion of time that the free drug concentration exceeded the MIC (%
f
T
>MIC
) and antibiotic efficacy was found for flomoxef, cefoxitin, and cefmetazole, and flomoxef had the highest %
f
T
>MIC
, whereas discrepancies between Clinical and Laboratory Standards Institute breakpoint and bactericidal activity were observed for cefmetazole. Flomoxef was effective in preventing the growth of all ESBL-producing strains, even those with an MIC eight times the MIC
90
. Thus, flomoxef may be a good alternative to meropenem in context of carbapenems sparing stewardship.
Epidemiology and risk factors for recurrence in biliary source bloodstream infection episodes in oncological patients
Authors: Grafia Ignacio , Chumbita Mariana , Seguí Elia , Cardozo Celia , Laguna Juan Carlos , García de Herreros Marta , Garcia-Pouton Nicole , Villaescusa Ana , Pitart Cristina , Rico-Caballero Verónica , Marco-Hernández Javier , Zamora Carles , Viladot Margarita , Padrosa Joan , Tuca Albert , Mayor-Vázquez Eric , Marco Francesc , Martínez Jose A. , Mensa Josep , Garcia-Vidal Carolina , Soriano Alex , Puerta-Alcalde Pedro 
Published: August 2023

ABSTRACT

We aimed to describe the characteristics and outcomes of biliary source bloodstream infections (BSIs) in oncological patients. Secondarily, we analyzed risk factors for recurrent BSI episodes. All episodes of biliary source BSIs in oncological patients were prospectively collected (2008–2019) and retrospectively analyzed. Logistic regression analyses were performed. A rule to stratify patients into risk groups for recurrent biliary source BSI was conducted. Four hundred biliary source BSIs were documented in 291 oncological patients. The most frequent causative agents were
Escherichia coli
(42%) and
Klebsiella
spp. (27%), and 86 (21.5%) episodes were caused by multidrug-resistant Gram-negative bacilli (MDR-GNB). The rates of MDR-GNB increased over time. Overall, 73 patients developed 118 recurrent BSI episodes. Independent risk factors for recurrent BSI episodes were prior antibiotic therapy (OR 3.781, 95% CI 1.906–7.503), biliary prosthesis (OR 2.232, 95% CI 1.157–4.305), prior admission due to suspected biliary source infection (OR 4.409, 95% CI 2.338–8.311), and BSI episode caused by an MDR-GNB (OR 2.857, 95% CI 1.389–5.874). With these variables, a score was generated that predicted recurrent biliary source BSI with an area under the receiver operating characteristic (ROC) curve of 0.819. Inappropriate empirical antibiotic treatment (IEAT) was administered in 23.8% of patients, and 30-d mortality was 19.5%. As a conclusion, biliary source BSI in oncological patients is mainly caused by GNB, with high and increasing MDR rates, frequent IEAT, and high mortality. Recurrent BSI episodes are frequent. A simple score to identify recurrent episodes was developed to potentially establish prophylactic strategies.

IMPORTANCE
This study shows that biliary source bloodstream infections (BSIs) in oncological patients are mainly caused by Gram-negative bacilli (GNB), with high and increasing rates of multidrug resistance. Importantly, recurrent biliary source BSI episodes were very frequent and associated with delays in chemotherapy, high rates of inappropriate empirical antibiotic therapy, and high 30-d mortality (19.5%). Using the variable independently associated with recurrent BSI episodes, a score was generated that predicted recurrent biliary source BSI with high accuracy. This score could be used to establish prophylactic strategies and lower the risk of relapsing episodes and the associated morbidity and mortality.
Large negative δ238U anomalies in endogenic-type travertine systems
Authors: Polyak Victor J. , Curry Brionna H. , Lavery Daniel J. , Strasberg Zachary L. , Cutler Savannah , Song Wenkai , Crossey Laura J. , Karlstrom Karl E. , Asmerom Yemane 
Published: August 2023

Abstract
We report exceptionally negative δ238U values for spring water (−2.5‰ to −0.8‰) and travertine calcite (−3.2‰ to −1.1‰) from an area where the Jemez lineament intersects the western margins of the Rio Grande rift, west-central New Mexico (southwestern United States). The highest anomalies come from the southern margins of the Valles Caldera and are related to upwelling CO2-charged spring water forming travertine mounds along joints and faults. The anomaly likely occurs due to CO2 lixiviation of uranium in a deep-seated reduced environment where 235U is preferentially leached along a long flow path through Precambrian granitic basement, resulting in spring water with exceptionally low δ238U values inherited by the calcite that precipitated near or at the surface at relatively low temperatures, i.e., ~40 °C (modern temperatures). The lowest δ238U values are preserved in settings where upwelling waters are least diluted by oxidized aquifer groundwaters. Given these low δ238U values in travertine are associated with and possibly indicators of upwelling CO2 related to tectonic and magmatic activity, studies such as ours may be used to identify this association far back in time.