bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of the International Consensus and 5th WHO edition classifications of adult myelodysplastic syndromes and acute myeloid leukemia
Authors: Falini Brunangelo , Martelli Maria Paola 
Published: January 2023

AbstractSeveral editions of the World Health Organization (WHO) classifications of lympho‐hemopoietic neoplasms in 2001, 2008, and 2016 served as the international standard for diagnosis. Since the 4th WHO edition, here referred as WHO‐HAEM4, significant clinico‐pathological, immunophenotypic, and molecular advances have been made in the field of myeloid neoplasms, which have contributed to refine diagnostic criteria, to upgrade entities previously defined as provisional and to identify new entities. This process has resulted in two recent classification proposals of myeloid neoplasms: the International Consensus Classification (ICC) and the 5th edition of the WHO classification (WHO‐HAEM5). In this paper, we review and compare the two classifications in terms of diagnostic criteria and entity definition, with a focus on adult myelodysplastic syndromes/neoplasms (MDS) and acute myeloid leukemia (AML). The goal is to provide a tool to facilitate the work of pathologists, hematologists and researchers involved in the diagnosis and treatment of these hematological malignancies.
Coherent quantum states in resonant‐mass gravitational wave detectors
Authors: Frajuca Carlos , Selbach Lucas , da Silva Douglas Alves , de Sales Dinalva Aires , Ferrari Fabricio , Magalhaes Nadja Simao 
Published: January 2023

AbstractThis work describes the importance of quantum coherent states when a resonant‐mass gravitational wave detector absorbs energy from a gravitational wave in an amount very close to the quantum limit. In this case, quantum non‐demolition measurements become essential as well. As the main result, for a coherent‐state signal, the detector behaves as if the signal was a classical one.
Determination of vegetable tannins from plants in China
Authors: Zhang Liangliang , Xu Man , Guan Qinhao , Jiang Jianchun , Sun Kang , Manirafasha Emmanuel 
Published: January 2023

AbstractTannin is a chemical compound found in plants such as tea, with yellow or brown as a characteristic color. Tannin is present in any plant species’ wood, stems, barks, leaves, roots, and fruits. However, the tannin contents in those plants are not the same and plants rich in tannin are the most used raw material for industrial‐level tannin extraction, such as chestnut. The central purpose of this article was to identify the tannin content of vegetables. In this study, tannins were extracted from 72 plants in China. The contents and purities of tannins, non‐tannins and insoluble substances in those studied plants were determined. A gravimetric approach, using hider powder as a precipitate to bind tannins, has been developed to quantify total tannins in plants. The results showed that high contents of tannins (>20%) were found in Pltycarya strobilacea fruit, Quercus acutissima shell, Quercus variabilis shell, Acacia mearnsii bark, Albizia kalkora bark, Camellia oleifera wood, Rosa cymosa root, Rosa laevigata root, Rhus chinensis gallnut, Bruguiera sexangular bark, Kandelia candel bark, Ceriops tagal bark, Lumnitzera racemose bark and Dioscorea cirrhosa tuber. The purity of tannins was more than 70% in some plants: Larix gmelimi bark, Causuarina equisetifolia bark, P. strobilacea fruit, Castanopsis tibetana wood, Quercus aliena shell, Quercus chenii shell and bark, A. mearnsii bark, A. kalkora bark, Bruguiera gymnorrhiza bark, C. tagal bark, K. candel bark and D. cirrhosa tubers. These plants are excellent resources for vegetable tannins in China. © 2023 Society of Industrial Chemistry and John Wiley & Sons Ltd.
How the anchor moves: Measuring and comparing the anchoring bias in autistic and neurotypical individuals
Authors: Rogge Nicky 
Published: January 2023

AbstractThe present paper is an exploratory study of the anchoring bias among individuals with autism. Anchoring bias is one of the most robust choice heuristics. The anchoring bias is measured and compared among adults with autism and age‐, gender‐, and education level‐matched, neurotypical controls. The study differentiates between high and low anchors. Results show that individuals with autism are generally equally susceptible to the anchoring bias as neurotypical individuals in judgment and decision making.
Emulsion‐assisted interfacial polymerization strategy: Controllable architectural engineering of anisotropic and isotropic nanoparticles for high‐performance supercapacitors
Authors: Liu Yumeng , Li Li , Zhang Liangliang , Han Gengxu , Liu Zhilin , Huang Jiaxing , Zhang Ling , Luo Jiahuan , Zhu Zhu , Qiao Zhen‐An 
Published: January 2023

AbstractAnisotropic nanoparticles have attracted extensive attention due to their potential applications in material transport, energy storage, and biopharmaceutical. However, due to the inadequate understanding of microscopic particle formation, controllable asymmetric growth is still a great challenge. Herein, we report a facile emulsion‐assisted interfacial polymerization strategy for the synthesis of nitrogen‐doped porous carbon particles (NPCPs) with tunable anisotropic/isotropic architectures. During the synthesis process, we can form emulsion droplets with different nanostructures directionally through dual routes, thereby assisting and mediating the polymerization and growth process of the monomer to obtain poly‐diaminopyridine nanoparticles with various architectures. The corresponding NPCPs with tunable specific surface area (125–362 m2 g−1), nitrogen content (10%–14%), and diverse morphologies can be acquired by calcination under N2 atmosphere at 700 °C. The synergetic effect of abundant microporous structures and active nitrogen species content contributes to improve the physicochemical properties, while the unique anisotropic architecture increases the charge diffusion efficiency and enhances the high‐rate stability. Therefore, the resultant NPCPs electrode exhibits a specific capacitance up to 275 F g−1 at 0.2 A g−1 and surface‐area‐normalized capacitance of 83.0 μF cm−2, indicating a promising material for high‐performance supercapacitors.
Mixed reality navigation training system for liver surgery based on a high‐definition human cross‐sectional anatomy data set
Authors: Shahbaz Muhammad , Miao Huachun , Farhaj Zeeshan , Gong Xin , Weikai Sun , Dong Wenqing , Jun Niu , Shuwei Liu , Yu Dexin 
Published: January 2023

AbstractObjectivesThis study aims to use the three‐dimensional (3D) mixed‐reality model of liver, entailing complex intrahepatic systems and to deeply study the anatomical structures and to promote the training, diagnosis and treatment of liver diseases.MethodsVascular perfusion human specimens were used for thin‐layer frozen milling to obtain liver cross‐sections. The 104‐megapixel‐high‐definition cross sectional data set was established and registered to achieve structure identification and manual segmentation. The digital model was reconstructed and data was used to print a 3D hepatic model. The model was combined with HoloLens mixed reality technology to reflect the complex relationships of intrahepatic systems. We simulated 3D patient specific anatomy for identification and preoperative planning, conducted a questionnaire survey, and evaluated the results.ResultsThe 3D digital model and 1:1 transparent and colored model of liver established truly reflected intrahepatic vessels and their complex relationships. The reconstructed model imported into HoloLens could be accurately matched with the 3D model. Only 7.7% participants could identify accessory hepatic veins. The depth and spatial‐relationship of intrahepatic structures were better understandable for 92%. The 100%, 84.6%, 69% and 84% believed the 3D models were useful in planning, safer surgical paths, reducing intraoperative complications and training of young surgeons respectively.ConclusionsA detailed 3D model can be reconstructed using the higher quality cross‐sectional anatomical data set. When combined with 3D printing and HoloLens technology, a novel hybrid‐reality navigation‐training system for liver surgery is created. Mixed Reality training is a worthy alternative to provide 3D information to clinicians and its possible application in surgery. This conclusion was obtained based on a questionnaire and evaluation. Surgeons with extensive experience in surgical operations perceived in the questionnaire that this technology might be useful in liver surgery, would help in precise preoperative planning, accurate intraoperative identification, and reduction of hepatic injury.
Comparative assessment of grain quality in tannin versus non‐tannin sorghums in the sorghum association panel
Authors: S. Impa M. , Bean Scott R. , loerger B. P. , Hayes Chad , Emendack Yves , Jagadish S. V. Krishna 
Published: January 2023

AbstractBackground and ObjectivesThe presence of antinutritional compounds such as tannins reduce the nutritional benefits in sorghum. Hence, the major objective was to evaluate the differences in grain quality and physical parameters in 254 tannin and non‐tannin accessions in a diverse set of sorghum association panel.FindingsWide variability was noticed for total protein (11%–19%) and protein digestibility (13%–78%). Tannin content recorded a significant negative relationship (R2 = 0.65, p < .001) with protein digestibility, indicating strong impact of tannins on protein digestibility in sorghum accessions with a pigmented testa. Non‐tannin accessions exhibited higher protein content, protein digestibility, kernel hardness, kernel weight and diameter, and lower phenolics compared to tannin accessions. Among the genetic races, Durra had the highest protein digestibility and Caudatum had the highest kernel weight than other races. In accessions with tannin, red grains had the highest tannin content and lowest protein digestibility than other colored grains.ConclusionsThe study revealed accessions with high protein digestibility of around 71% in both non‐tannin and tannin groups. A tannin containing accession SC1056 had the highest protein digestibility (78%) coupled with high kernel hardness.Significance and NoveltyAccessions with above‐average protein digestibility, either with or without tannins could be ideal donors for breeding for improved grain quality in sorghum.
Tumor‐to‐tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
Authors: Mansikka Iisa , Kinnunen Ilpo , Hirvonen Jussi , Vainio Paula , Velhonoja Jarno 
Published: January 2023

AbstractMetastases of distant primary tumors on the parotid gland are very rare. Tumor‐to‐tumor metastasis to salivary gland tumors is extremely rare. A case of a 69‐year‐old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine‐needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary breast cancer. A negative FNA does not rule out the possibility of a malignant parotid tumor or metastasis, and a parotid lump should be presumed to be a secondary tumor until proven otherwise if the patient has a history of any distant primary cancer. Our patient case serves as a reminder that a new distant primary cancer might be the cause of a parotid lump.
Defect‐Induced Activity Enhancement of Self‐Exfoliated Carbon Nitrides for Solar Hydrogen Evolution
Authors: Zhu Chaofeng , Wang Yang , Xue Jiawei 
Published: January 2023

AbstractThe recombination of photogenerated electron‐hole pairs severely limits the efficiency of solar‐driven hydrogen evolution in carbon nitrides (CN) system. Herein, a K+ doped and cyanamide defects modified CN (CCNK) with free‐standing nanosheets in water was synthesized by a bottom‐up self‐exfoliated strategy. Further experimental characterizations reveal that the cyanamide moiety and K+ in the framework play an important role in the enhancement of hydrophilicity and efficiently suppress electron‐hole pair recombination. CCNK exhibits an impressive photocatalytic hydrogen evolution activity (132.6 μmol h−1), which is 22 times higher than bulk CN (6.0 μmol h−1), and far surpassing other CN‐based photocatalysts. This work provides an innovative facile self‐exfoliated strategy for bottom‐up preparation of ultrathin CN nanosheets without using any acid, base, or solvents, paving the way for the development of high‐performance photocatalysts using CN‐based powders.
Polyethylenimine‐Grafted Silica Nanoparticles Facilitate Enzymatic Carbon Dioxide Conversion
Authors: Liu Yu , Li Yu-Tong , Liu Ling , Bai Shu , Yu Lin-Ling , Sun Yan 
Published: January 2023

AbstractPolyethylenimine (PEI)‐grafted silica nanoparticles were fabricated and characterized for the electrostatic immobilization of a CO2 conversion enzyme. PEI was supposed to serve as a carbonic anhydrase mimic for CO2 capture and conversion to HCO3− (the optimal substrate of many CO2 conversion enzymes) and was proved to assist phosphoenolpyruvate carboxylase to form a dual‐enzyme cascade system for CO2 conversion. The immobilized enzyme not only presented better thermostability, pH tolerance, and storage stability, but also enhanced the specific activity (three‐ and fourfold for HCO3− and CO2 as the substrates, respectively), with good reusability and low cost. It was proven that PEI‐grafted nanoparticles are highly efficient nanocarriers for immobilizing CO2‐converting enzymes in industrial applications.
Base‐Mediated Radio‐Iodination of Arenes by Using Organosilane and Organogermane as Radiolabelling Precursors
Authors: Bloux Hugo , Dahiya Amit , Hébert Alexandra , Fabis Frédéric , Schoenebeck Franziska , Cailly Thomas 
Published: January 2023

AbstractThe radio‐iodination of arenes is investigated from organosilane and organogermane precursors using ipso‐electrophilic halogenation (IEH). Discovery of a mild base mediated process allows radio‐iodination in HFIP (1,1,1,3,3,3‐hexafluoro‐2‐propanol) of either aryl silane or germane, with germanes being more reactive. Clinical potential of arylgermanes as radio‐iodination precursors is demonstrated through the labelling of [125I]IMTO (iodometomidate) and [125I]MIBG (meta‐iodobenzylguanidine) thus offering an alternative to radio‐iododestannylation processes using non‐toxic precursors.
α‐Amination of Carbonyl Compounds by Using Hypervalent Iodine‐Based Aminating Reagents Containing a Transferable (Diarylmethylene)amino Group
Authors: Okumatsu Daichi , Kawanaka Kazuki , Kainuma Shunpei , Kiyokawa Kensuke , Minakata Satoshi 
Published: January 2023

AbstractHypervalent iodine‐based aminating reagents containing a transferable (diarylmethylene)amino group can be used for the α‐amination of simple carbonyl compounds such as esters, amides, and ketones in the presence of a lithium base. The (diarylmethylene)amino groups of the products can be readily modified, thus providing access to primary amines and diarylmethylamines. The developed method features transition‐metal‐free conditions and a simple one‐pot procedure without the need to prepare enolate equivalents separately, thus offering a general and practical approach to the synthesis of a wide variety of α‐amino carbonyl compounds. Experimental mechanistic investigations indicate that this amination proceeds through a unique radical coupling of an α‐carbonyl radical with an iminyl radical; they are generated through a single‐electron transfer between a lithium enolate and the hypervalent iodine reagent.
Simulationsstrategie zur belastbaren Auslegung der Essigsäure‐Rückgewinnung aus Abwässern der industriellen Celluloseacetatherstellung
Authors: Millenautzki Thomas , Tempel Tasia , Barbe Stéphan 
Published: January 2023

AbstractBei der industriellen Acetylierung von Cellulose fallen große Mengen an essigsäurehaltigem Abwasser an. Im Sinne der Nachhaltigkeit und der zirkularen Wertschöpfung ist es entscheidend, die Essigsäure zurückzugewinnen und zu recyceln (closed loop). In dieser Arbeit wurde eine Simulationsstrategie zur belastbaren Auslegung der Rückgewinnung von Essigsäure aus Abwässern der industriellen Celluloseacetatherstellung entwickelt und experimentell validiert. Dabei wurden die entsprechenden Modelle (NRTL & UNIFAC) diskutiert und für Simulationen eingesetzt. Die Praxiswerte bestätigten die Vermutung der praktischen Anwendbarkeit des NRTL‐Aktivitätskoeffizienten von αij = 0,2.
Influence of weak electrostatic charges and secondary flows on pneumatic powder transport
Authors: Grosshans Holger 
Published: January 2023

AbstractThe dynamics of the transported powder determines the functionality and safety of pneumatic conveying systems. The relation between the carrier gas flow, induced by the flown‐through geometry, and the powder flow pattern is not clear yet for electrostatically charged particles. This paper highlights the influence of relatively minor cross‐sectional secondary flows and electrostatic forces on the concentration and dynamics of the particles. To this end, direct numerical simulations (DNS) capture the interaction of the continuous and dispersed phases using a four‐way coupled Eulerian–Lagrangian strategy. The transport of weakly charged particles in channel flows, where turbopheresis defines the particle concentration, is compared to duct flows, where additional cross‐sectional vortices form. For both geometries, the Stokes number () and the electrical Stokes number () are varied, and the turbulent carrier flow was fixed to . The presented simulations demonstrate that secondary flows, for the same , , and , dampen the effect of particle charge. In a duct flow, vortical secondary flows enhance the cross‐sectional particle mobility against the direction of electrostatic forces. Compared to a duct flow, in a channel, the wall‐normal aerodynamic forces are weaker. Thus, electrical forces dominate their transport; the local particle concentration at the walls increases. Further, electrostatic charges cause a stronger correlation between the gas and particle velocities. In conclusion, despite being weak compared to the primary flow forces, secondary flow and electrostatic forces drive particle dynamics during pneumatic transport.
Carfentanil structural analogs found in street drugs by paper spray mass spectrometry and their characterization by high‐resolution mass spectrometry
Authors: Borden Scott A. , Mercer Savannah R. , Saatchi Armin , Wong Ernest , Stefan Cristiana M. , Wiebe Heather , Hore Dennis K. , Wallace Bruce , Gill Chris G. 
Published: January 2023

AbstractCarfentanil is one of the most potent synthetic opioids ever developed, with an estimated analgesic potency approximately 20–100 times that of fentanyl and 10,000 times that of morphine. Carfentanil has been appearing in the illicit drug supply in many regions and has been linked to fatal overdose events. A subset of 59 street drug samples obtained in Victoria, B.C., that were confirmed to contain carfentanil were analyzed by mass spectrometry for this study. Carfentanil quantitation by paper spray mass spectrometry ranged from 0.05 to 2.95 w/w% (median = 0.32%) in the original drug sample. Paper spray mass spectrometry analysis also detected two unknown peaks at m/z 380.2 and 381.2 in 31 of these 59 samples (53%). Initial tandem mass spectrometry experiments revealed structural similarities between these unknown compounds and carfentanil, suggesting they were potential structural analogs, possibly arising from incomplete purification during synthesis. High‐resolution mass spectrometry determined the chemical formulas of these compounds as C23H29N3O2 (m/z 380.2333) and C23H29N2O3 (m/z 381.2137). Literature and tandem mass spectrometry results were used to determine the identity of these potential new psychoactive substances, C23H29N3O2 as desmethylcarfentanil amide and C23H29N2O3 as desmethylcarfentanil acid. μ‐Opioid receptor binding modeling determined that the binding poses of these analogs were nearly identical to that of carfentanil with relative binding energy calculations of 0.544 kJ/mol (desmethylcarfentanil amide) and −0.171 kJ/mol (desmethylcarfentanil acid); these data suggest they may share the toxic effects of carfentanil and have similar potencies.
Differences in the behavior and diet between shoaling and solitary surgeonfish (Acanthurus triostegus)
Authors: Guerra Ana Sofia , Van Wert Jacey C. , Haupt Alison J. , McCauley Douglas J. , Eliason Erika J. , Young Hillary S. , Lecchini David , White Timothy D. , Caselle Jennifer E. 
Published: January 2023

AbstractVariation in behavior within marine and terrestrial species can influence the functioning of the ecosystems they inhabit. However, the contribution of social behavior to ecosystem function remains underexplored. Many coral reef fish species provide potentially insightful models for exploring how social behavior shapes ecological function because they exhibit radical intraspecific variation in sociality within a shared habitat. Here, we provide an empirical exploration on how the ecological function of a shoaling surgeonfish (Acanthurus triostegus) may differ from that of solitary conspecifics on two Pacific coral reefs combining insight from behavioral observations, stable isotope analysis, and macronutrient analysis of gut and fecal matter. We detected important differences in how the social mode ofA. triostegusaffected its spatial and feeding ecology, as well as that of other reef fish species. Specifically, we found increased distance traveled and area covered by shoaling fish relative to solitaryA. triostegus. Additionally, shoalingA. triostegusprimarily grazed within territories of other herbivorous fish and had piscivorous and nonpiscivorous heterospecific fish associated with the shoal, while solitaryA. triostegusgrazed largely grazed outside of any territories and did not have any such interactions with heterospecific fish. Results from stable isotope analysis show a difference in δ15N isotopes between shoaling and solitary fish, which suggests that these different social modes are persistent. Further, we found a strong interaction between social behavior and site and carbohydrate and protein percentages in the macronutrient analysis, indicating that these differences in sociality are associated with measurable differences in both the feeding ecology and nutrient excretion patterns. Our study suggests that the social behavior of individuals may play an important and underappreciated role in mediating their ecological function.