bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment for Learning of Design Teamwork Skills
Authors: Tessier Virginie , Carbonneau‐Loiselle Mathilde 
Published: May 2023

AbstractThis article seeks to contribute to the reflection around the training of future designers regarding teamwork. Collaboration, teamwork and negotiations are common everyday interactions that are now known to contribute positively to the design process. This article builds on a theoretical model that was initially proposed as a Ph.D. thesis contribution: the zone of proximal development for learning teamwork skills. The objective of this article is to share the first implementation of the model in a real educational situation and seize this opportunity to develop it further. The framework of assessment for learning and the concept of the zone of proximal development guide this research. The data collection is based on the observations of teamwork during a design seminar. The analysis is structured around the theoretical definitions of the model's components and in situ observations of the participants. This process guides us to share indicators allowing to confirm if a level or set of skills are achieved by a student. Plus, we propose a set of related teaching guidance to use when skills are identified as underdeveloped or to develop. Through this work, we wish to discuss how design students can be better equipped to enter the profession and play a significant role as team players.
Modularization of the front‐end logistics services in e‐fulfillment
Authors: Yurt Oznur , Sorkun Metehan Feridun , Hsuan Juliana 
Published: May 2023

AbstractThis study exploits service modularity in front‐end logistics services in e‐fulfillment, from a customer‐centric approach, particularly in order management, delivery, and return. Through an online survey of UK customers, the service priorities of 494 respondents via AHP (Analytic Hierarchical Process) were analyzed. Extracting customers' service priorities, ordering behavior, and demographic information as input data, the clustering algorithm KAMILA (KAy‐means for MIxed LArge data sets) was further applied. The three identified customer clusters (multichannel shoppers, infrequent shoppers, and online fans) provide preliminary evidence on how commonality and variability aspects of service modularity in front‐end logistics services can optimize the number of service options and their performance levels. Therefore, our study, building on value co‐creation and modularity, proposes a systematic way of exploiting service modularity for the customer segmentation process that addresses heterogeneous customer preferences cost‐efficiently and uncomplicatedly. Furthermore, we provide a framework for the governance of front‐end logistics services, guiding outsourcing decisions. Accordingly, it reveals the implications of customer priorities and service decomposition logic choices on value creation. Finally, the propositions formulated aim to develop theoretical foundations for explaining how the heterogeneity in customer priorities for logistics services can be managed with modularity, creating value both for customers and retailers.
Mass transfer and color change kinetics of infrared drying of rose petals and its impact on physico‐chemical properties
Authors: Aradwad Pramod , Yadav Rahul , Arun Kumar T. V. , Shabeer T. P. Ahammed , Raju D. V. S. , Kumar P. Naveen , Sahoo Monalisa 
Published: May 2023

AbstractThe present study investigated the effects of infrared and forced convective air at different infrared power levels (300, 400, and 500 W) and hot air temperatures (50, 57, and 65°C) on thin layer drying of rose petals. Infrared drying requires 50%–52% less time as compared with forced convective drying. The initial and final moisture content of rose petals were 84% (w.b.) and 4.5% (w.b.) respectively. The Midilli–Kucuk model gives a superior fit for both the drying methods followed by Avhad and Marchetti, and the Page model. The zero‐order, followed by the first‐order color kinetics model gives the best fitting for L*, a*, and b* values. Moisture diffusivity was increased by infrared power (1.7308 × 10−8 to 4.1495 × 10−8 m2/s) and hot air temperature (9.3715 × 10−9 to 1.1709 × 10−8 m2/s). The activation energy obtained for rose petals in hot air dryers and infrared dryers was 51.09 kJ/mol and 6.50 kW/kg, respectively. Samples dried at 500 W infrared drying for 18 min demonstrated higher retention of color, ascorbic acid (61.03 ± 2.6 mg/100 g), and anthocyanin content (295.75 ± 65.70 mg/100 g) in the rose petals.Practical ApplicationsSeveral drying techniques are available, though continuous efforts have been made to improve drying methods in terms of energy efficiency and product quality attributes. The present work has been carried out considering the dearth of information on the influence of infrared power/intensity on drying behavior and product quality of rose petals. Mass and color kinetics has been studied for a better understanding of the process along with rehydration, ascorbic acid and anthocyanin content. Our results showed that the infrared drying has significant industrial importance as it provides an efficient way to dry flowers, preserving their quality and extending their shelf life.
Sex and single women in midlife: Theoretical perspectives, recent findings, and future directions
Authors: Luke Nancy , Poulin Michelle 
Published: May 2023

AbstractDemographic trends, such as the graying of divorce, have led to increasing numbers of unmarried women in midlife, yet little is known about the meaning of sex and intimacy among this population. This article reviews the nascent literature on single women's sexual experiences at midlife, theoretical frameworks that have been employed, and key findings. Challenging the stereotype that single women in midlife are in sexual decline, research shows that many women embrace their newfound freedom, have increased agency in midlife, and have positive sexual experiences. Others face impediments to finding new partners and engaging in sexual activity, including the lasting effects of abuse from previous relationships and restrictive social norms. For some, sex becomes less important in midlife, often replaced by close relationships with family and friends. Research largely focuses on White, heterosexual women; research on the experiences of racial and sexual minorities and midlife women in the Global South is needed.
Plastid KEA‐type cation/H+ antiporters are required for vacuolar protein trafficking in Arabidopsis
Authors: Zhang Xiao , Wang Lu , Pan Ting , Wu Xuexia , Shen Jinbo , Jiang Liwen , Tajima Hiromi , Blumwald Eduardo , Qiu Quan‐Sheng 
Published: May 2023

AbstractArabidopsis plastid antiporters KEA1 and KEA2 are critical for plastid development, photosynthetic efficiency, and plant development. Here, we show that KEA1 and KEA2 are involved in vacuolar protein trafficking. Genetic analyses found that the kea1 kea2 mutants had short siliques, small seeds, and short seedlings. Molecular and biochemical assays showed that seed storage proteins were missorted out of the cell and the precursor proteins were accumulated in kea1 kea2. Protein storage vacuoles (PSVs) were smaller in kea1 kea2. Further analyses showed that endosomal trafficking in kea1 kea2 was compromised. Vacuolar sorting receptor 1 (VSR1) subcellular localizations, VSR–cargo interactions, and p24 distribution on the endoplasmic reticulum (ER) and Golgi apparatus were affected in kea1 kea2. Moreover, plastid stromule growth was reduced and plastid association with the endomembrane compartments was disrupted in kea1 kea2. Stromule growth was regulated by the cellular pH and K+ homeostasis maintained by KEA1 and KEA2. The organellar pH along the trafficking pathway was altered in kea1 kea2. Overall, KEA1 and KEA2 regulate vacuolar trafficking by controlling the function of plastid stromules via adjusting pH and K+ homeostasis.
Differentiation of strains in the lateral and medial bands of the iliofemoral ligament: A segmental approach
Authors: St‐Pierre Marc‐Olivier , Effatparvar Mohammad Reza , Begon Mickaël , Sobczak Stéphane 
Published: May 2023

AbstractIliofemoral ligament strains have been assessed in a circumscribed portion, limiting the information regarding the strains in the proximal, mid and distal portions. The purpose of this study is to describe the longitudinal and transversal strain within the proximal, mid and distal portions of the lateral and medial bands of the iliofemoral ligament. Ten fresh cadaveric specimens were assessed. The iliofemoral ligaments were divided into medial and lateral bands. Hemispherical beads (2.6 mm) were placed on the lateral and medial borders of each band. Four positions were assessed: abduction, extension, internal and external rotations combined with extension. The hemispherical beads were scanned at the end range of motion using a laser scanner. The three‐dimensional position of each bead was used to estimate longitudinal and transversal strains. A three‐factor ANOVA was used to compare movements, borders, and portions within each ligament for longitudinal strains. A one‐way ANOVA was used to compare transversal strains between portions. This technique showed mean reliability (ICC: 2, 1) of 0.90 ± 0.06. The external rotation showed the highest strains in both ligaments (p < 0.05). Abduction showed a significant difference between the lateral and medial borders in both bands (p = 0.001). Eight movement‐border combinations showed a significant difference between proximal, medial, and lateral portions (p < 0.005). According to our results, there is a clear effect of portions (proximal, mid and distal) within the ligament and movements. Abduction shows the lowest strains longitudinally but the largest strains transversally. Although we do not know the impact of this phenomenon, future studies should assess the strains following hip arthroscopies. The latter might improve the impact of this procedure on hip biomechanics. Lastly, the iliofemoral ligament should be assessed using a segmental approach rather than as a complete unit.
Ghost infarct core: A systematic review of the frequency, magnitude, and variables of CT perfusion overestimation
Authors: Ballout Ahmad A. , Oh Seok Yoon , Huang Brendan , Patsalides Athos , Libman Richard B. 
Published: May 2023

AbstractBackground and PurposeCT perfusion (CTP) imaging is now widely used to select patients with large vessel occlusions for mechanical thrombectomy. Ghost infarct core (GIC) phenomenon has been coined to describe CTP core overestimation and has been investigated in several retrospective studies. Our aim is to review the frequency, magnitude, and variables associated with this phenomenon.MethodsA primary literature search resulted in eight studies documenting median time from symptom onset to CTP, median estimated core size, median final infarct volume, median core overestimation of the GIC population, recanalization rates, good outcomes, and collateral status for this systematic review.ResultsAll the studies investigated patients who underwent CTP within 6 hours of symptom onset, ranging from median times of 105 to 309 minutes. The frequency of core overestimation varied from 6% to 58.4%, while the median estimated ischemic core and final infarction volume ranged from 7 to 27 mL and 12 to 31 mL, respectively. The median core overestimation ranged from 3.6 to 30 mL with upper quartile ranges up to 58 mL. GIC was found to be a highly time‐and‐collateral‐dependent process that increases in frequency and magnitude as the time from symptom onset to imaging decreases and in the presence of poor collaterals.ConclusionsCTP ischemic core overestimation appears to be a relatively common phenomenon that is most frequent in patients with poor collaterals imaged within the acute time window. Early perfusion imaging should be interpreted with caution to prevent the inadvertent exclusion of patients from highly effective reperfusion therapies.
Exploring the structure of fearlessness using self‐report measures
Authors: Van Til Kaela , Miller Joshua D. , Carter Nathan T. , Lynam Donald R. 
Published: May 2023

AbstractObjectiveThe present study examined the hierarchical structure of self‐reported fearlessness and compared this structure to external criterion measures.BackgroundFearlessness is often discussed in relation to clinical and personality research. However, there is a paucity of research focusing on its empirical structure, in particular with self‐report measures.MethodUsing a preregistered analytical approach, we employed Goldberg's 2006 “bass‐ackward” factor analysis on self‐reported trait fear and fearlessness items to uncover the hierarchical structure of the construct. The final sample consisted of 619 participants and 562 informants.ResultsBy assessing fit statistics and interpretability of the factors, we found a six‐factor model fit the data best. The six‐factor solution emerged as comprehensive and included components labeled Assertiveness, Low Anxiety, Sociability, Recklessness, Openness to Action, and Adventurousness. Criterion variables measuring boldness, fear, anxiety, psychopathy, basic personality traits, and impulsivity, were correlated with the factor scores at each factor level of the model.
Conclusions
The findings from this study elucidate how trait fearlessness unfolds at varying levels and how these factors relate to and diverge from various outcomes.
Religious Homogamy and Marital Satisfaction in South Korea: Exploring Variations across Religious Groups
Authors: Lee Sangsoo , Lee Myoung‐Jin 
Published: May 2023

AbstractThis study examines whether and how the association between religious homogamy (i.e., whether spouses have the same religious affiliation) and marital satisfaction varies across religious affiliations by utilizing a unique context that four large religious groups (i.e., Buddhists, Protestants, Catholics, and religious nones) coexist in South Korea. Our results show that while religious homogamy has a positive relationship with marital satisfaction among Protestants and Catholics, there is no such association among Buddhists. This study also reveals that higher levels of religious attendance intensify the positive relationship between religious homogamy and marital satisfaction only among Protestants. Moreover, religious heterogamy is positively associated with marital relationships among religious nones compared to religious homogamy. However, this pattern held only for religious nones who married Buddhists or Catholics. We discuss the implications of our findings for research on religion and marriage from cross‐cultural perspectives.
Career arduousness and instability: Both matter for health beyond 50
Authors: Vandenberghe Vincent 
Published: May 2023

AbstractThis paper explores the long‐term consequences of career arduousness and career instability for both physical and mental health in the European context. One of its strengths is to link what happens during the entire career and the health status at an older age. The paper finds a positive link between career arduousness (i.e. the sum of job demands individuals have been exposed to during their entire career) and late‐life mental and physical ill health, but also evidence that career instability (i.e. career gaps, job insecurity, displacements, unemployment spells) could matter as much as arduousness per se. And this has implications for pension policy inter alia.
Safety and efficacy of venous thromboembolism prophylaxis in patients with cirrhosis: A systematic review and meta‐analysis
Authors: Pasta Andrea , Calabrese Francesco , Labanca Sara , Marenco Simona , Pieri Giulia , Plaz Torres Maria Corina , Intagliata Nicolas M. , Caldwell Stephen H. , Giannini Edoardo G. 
Published: May 2023

AbstractBackground & AimsPatients with cirrhosis are considered in a haemostatic balance, though weaker than in normal subjects. In these patients, however, the use of pharmacological prophylaxis for venous thromboembolism (VTE) remains controversial. Therefore, in this study, we aimed to assess the safety and efficacy of VTE prophylaxis in patients with cirrhosis.MethodsWe conducted a systematic review of studies reporting the occurrence of bleeding and VTE events in patients with cirrhosis, and controls, undergoing VTE prophylaxis. Meta‐regression analysis was conducted to further explore the determinants of heterogeneity in the study of the occurrence of either bleeding or VTE events.ResultsIn a total of 10 studies, including 5712 patients, of which 2330 undergoing VTE prophylaxis, bleeding (n = 5513) and VTE events occurred in 8.2% and 2.8% patients respectively. A total of 2963 and 3162 patients were included from low‐risk of bias studies in bleeding and VTE analysis respectively: while administration of VTE prophylaxis did not seem to reduce VTE (OR = 1.07, CI 0.39–2.96, p = .89), importantly prophylaxis was not associated with increased bleeding risk (OR = 0.56, CI 0.20–1.59, p = .27). Meta‐regression analysis showed that no parameter significantly influenced the heterogeneity of data regarding bleeding or VTE events.ConclusionsIn patients with cirrhosis, current evidence is insufficient to advise for or against the use of VTE prophylaxis, mainly due to lack of quality and homogeneity of available data. However, its use does not appear to be associated with a significant bleeding risk. Adequately designed studies are required to provide a measure of its overall utility.
Usefulness of controlled attenuation parameter in monitoring clinically relevant decline of hepatic steatosis for non‐alcoholic fatty liver disease
Authors: Wang Jing‐Houng , Ou Hsin‐You , Yen Yi‐Hao , Hung Chao‐Hung , Lu Sheng‐Nan 
Published: May 2023

AbstractBackground and AimsMagnetic resonance imaging‐derived proton density fat fraction (MRI‐PDFF) is the reference standard of hepatic steatosis assessment. This study evaluates usefulness of controlled attenuation parameter (CAP) in monitoring the clinically relevant outcome by MRI‐PDFF for non‐alcoholic fatty liver disease (NAFLD) patients.MethodsNAFLD patients were enrolled prospectively. Instruction was given in lifestyle modifications with exercise and control of metabolic factors. MRI‐PDFF and CAP were performed at enrollment and follow‐up, with the diagnostic validity of CAP in monitoring clinically relevant outcome defined as a decline of ≥30% relative to baseline value by MRI‐PDFF.ResultsA total of 75 patients (male/female: 49/26, mean age: 53.2) were enrolled. Baseline MRI‐PDFF, CAP and liver stiffness was 14.4%, 300.2 dB/m and 6.5 kPa. In a median interval of 369 days, thirteen (17.3%) patients achieved clinically relevant outcome with decline of 46.7 dB/m by CAP, compared with increase of 5.1 in the other patients. In multivariate analysis, clinically relevant outcome was associated with changes (Δ) of CAP and glucose. Assessed by area under receiver operating curve, the performances of ΔCAP in predicting clinically relevant outcome were 0.815 and 0.808, and with the specificity of >90%, the ΔCAP cutoff was −46 dB/m and −15% relative to baseline value; sensitivity was 53.8% and 46.2% with negative predictive value of 90.3% and 88.9% respectively.ConclusionsFor NAFLD patients, CAP exhibited good performance in monitoring clinically relevant decline of hepatic steatosis in MRI‐PDFF. With the cutoffs of −46 dB/m or −15%, ΔCAP is useful in excluding clinical relevant outcome achievement.
Intensive care nurses' experiences of caring for patients during the COVID‐19 pandemic based on an analysis of blog posts
Authors: Skoglund Karin , Åhlman Ebba , Mallin Sofia , Holmgren Jessica 
Published: May 2023

AbstractBackgroundIn 2019, coronavirus disease 2019 (COVID‐19) broke out worldwide, leading to a pandemic. Studies have shown that COVID‐19 patients in intensive care units (ICUs) require more nursing care than other patients. ICU nurses who care for patients with COVID‐19 have shown signs of psychological and physical strain.AimThe aim of this study was to illuminate ICU nurses' experiences of caring for patients with COVID‐19 in ICUs during the first wave of the pandemic.Study DesignA qualitative, descriptive and inductive approach was used. A total of 70 blog posts from 13 bloggers in the United States, Great Britain, Finland and Sweden were analysed using qualitative inductive manifest content analysis.ResultsThe results reveal an overall theme: ‘An overturned existence under extreme conditions’. Furthermore, three categories—‘the virus caused changes in work and private lives’, ‘unreasonable demands’, and to hold on to caring ideals thanks to the support of others’—and seven subcategories were identified.ConclusionsCaring for patients with COVID‐19 during the first wave of the pandemic was demanding because of a lack of knowledge about the disease and the severity of the illness. This led to ICU nurses experiencing extreme conditions that affected various aspects of their lives. Support from colleagues and teamwork were revealed to be particularly important for how nurses dealt with the demands of working during a pandemic, as was sufficient recovery time between work shifts.Relevance to Clinical PracticeWork in ICUs was challenging and demanding, even before the pandemic. This study contributes to an understanding of the complex work environment that existed in hospitals during the first wave of the COVID‐19 pandemic. The knowledge obtained from this study can be used to revise working conditions and identify health interventions for ICU nurses.
Mesenchymal stem cells‐derived IL‐6 promotes invasion and metastasis of oral squamous cell carcinoma via JAK‐STAT3 signalling
Authors: Liu Chuanxia , Zhou Jinhan , Zhang Shanshan , Fu Ji , Li Yining , Hao Yilong , Yuan Jian , Tang Fan , Ge Weili , He Hong , Chen Qianming 
Published: May 2023

AbstractObjectivesOral squamous cell carcinoma (OSCC) is often diagnosed with cervical lymph node metastasis. Mesenchymal stem cells (MSCs) and interleukin‐6 (IL‐6) signalling are considered to play important roles in promoting tumour malignancy. The detailed biological interaction of MSCs and IL‐6 and the subsequent effect on OSCC metastasis remain largely unclear. This study aimed to determine the effects and molecular mechanism of MSCs‐derived IL‐6 on tumour invasion and metastasis.Subjects and MethodsThe effects of MSC‐derived IL‐6 and tocilizumab on the proliferation, mobility, and epithelial‐mesenchymal transition (EMT) of OSCC cells and potential pathways were detected in vitro. In addition, a murine xenograft model was generated to verify the biological mechanism in vivo.ResultsThe results showed that the expression of MSCs and EMT‐related signals was increased in poorly differentiated OSCC tissues. MSCs released a higher level of IL‐6 and promoted the proliferation, invasion, and metastasis of OSCC cells and solid neoplasms, which were activated by the downstream molecules JAK and STAT3.ConclusionsThe results indicated that MSCs‐derived IL‐6‐promoted tumour invasion and metastasis via JAK–STAT3 signalling. Blockade of this pathway by tocilizumab may be a potential treatment to improve the prognosis and survival rate of patients with OSCC.