bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and molecular docking studies of novel tricyclic and angular tetracyclic benzothiadiazines via sp3‐C‐Hactivation as potential colon cancer inhibitors
Authors: Kolade Sherif O. , Aina Oluwafemi S. , Gordon Allen T. , Hosten Eric C. , Olasupo Idris A. , Ogunlaja Adeniyi S. , Asekun Olayinka T. , Familoni Oluwole B. 
Published: August 2023

AbstractThis paper describes the synthesis of tricyclic and tetracyclic benzothiadiazines and their derivatives, which are known for their versatility as bioactive agents. The starting materials were N‐cycloamino‐4‐substituted‐2‐nitrobenzenesulfonamides 8–16, which were prepared through the condensation of 4‐substituted‐2‐nitrobenzenesulfonyl chlorides 1–3 and cyclic amines 4–7. The intermediates, N‐cycloamino‐4‐substituted‐2‐sulfanilamides 17–25, were obtained through catalytic hydrogenation of N‐cycloamino‐4‐substituted‐2‐nitrobenzenesulfonamides 8–16 using a 10% palladium‐on‐charcoal catalyst. The potentially bioactive tricyclic and angular tetracyclic 1,2,4‐benzothiadizine dioxides 26–34 were then synthesized via metal‐free intramolecular N‐iodosuccinimide (NIS)‐mediated radical oxidative sp3‐C‐H activation aminative cyclization of N‐cycloamino‐4‐substituted‐2‐sulfanilamides 17–25. The yields were good to excellent (68–93%). Docking studies were conducted for N‐cycloamino‐4‐substituted‐2‐nitrobenzenesulfonamides 8–16, N‐cycloamino‐4‐substituted‐2‐sulfanilamides 17–25, and tricyclic and angular tetracyclic 1,2,4‐benzothiadizine dioxides 26–34 for colon cancer using five protein molecules. The results showed that most of the prepared ligands exhibited higher activity than the reference drugs capecitabine, capecitabine, and fluorouracil. Among the compounds synthesized, KS7, a benzothiadiazine, showed the best activity against 6KRO.
Fairness uncertainty and pay information exchange: Why and when employees disclose bonus pay to pay information websites
Authors: Brown Michelle , Bamberger Peter , Bliese Paul D. , Shields John 
Published: August 2023

SummaryHaving limited information regarding how pay is distributed in their organization, employees often find it difficult to assess the fairness of their pay. Uncertainty management theory (UMT) posits that fairness uncertainty is aversive and that individuals experiencing it search for information to reduce this uncertainty. Pay information exchange – the communication of one's pay‐related information to others in return for information from that other – provides a mechanism to reduce pay information uncertainty. We focus on third‐party mediated pay information exchange (such as via Glassdoor and PayScale), an increasingly prevalent form of exchange. Drawing on UMT, we investigate why and when individuals exchange their pay information with such agents. Using data from a field experiment we find that (a) the willingness of employees to disclose their pay to a pay information exchange platform is influenced by perceived utility of a‐priori information offered by the exchange partner, but that this relationship depends on the salience of fairness uncertainty to the employee, and (b) employer pay communication restrictiveness only attenuates the impact of disclosure willingness on actual disclosure when individuals engage in deliberative thinking about such restrictiveness and its possible consequences. We discuss the implications for theory and practice.
An Injectable, Adhesive, and Self‐Healing Hydrogel with Inherently Antibacterial Property for Wound Dressing
Authors: Jiang Hanwen , Xiao Yan , Huang Huanxuan , Yin Wang , Lang Meidong 
Published: August 2023

AbstractAntibacterial hydrogel has emerged as an excellent candidate for wound dressing with the ability to eliminate infection and promote wound healing. Herein, a dynamic hydrogel is developed by Schiff base reaction of mixed charged polypeptides and oxidized dextran (ODex). Specifically, biodegradable polypeptides of 1‐(propylthio)acetic acid‐3‐butylimidazole‐modified poly(L‐lysine) (PLL‐PBIM) and adipate dihydrazide‐modified poly(L‐glutamic acid) (PLG‐ADH) are achieved with tunable substitution and charge. By mixing with ODex, charged polypeptides of PLL‐PBIM and PLG‐ADH led to an injectable and self‐healing hydrogel in seconds. The injectable and self‐healing performances of the hydrogels are ascribed to the reversible imine and hydrazone bonds formed between polypeptides and ODex. The positively charged hydrogels exhibited over 95% antibacterial activity against E. coli and S. aureus. An optimized balancing of PLG‐ADH and PLL‐PBIM significantly reduced the hemolysis rate and cytotoxicity of hydrogels. Therefore, the dynamic hydrogel with excellent biocompatibility and inherently antibacterial ability can have potential application for wound dressing.
Angular and linear velocity observer design using vector and landmark measurements
Authors: Zhu Hangbiao , Gui Haichao 
Published: August 2023

AbstractThis paper presents an approach for designing angular and linear velocity observers for rigid bodies using two inertial vectors and one landmark measurements directly. Compared with the classical velocity estimation algorithms, the proposed observer does not need to reconstruct the pose information from measurements nor be coupled with velocity sensors. The linear‐time varying dynamics of the estimation error equation are analyzed, rigorously showing the uniform local exponential stability of the observer. Simulations are conducted to illustrate the significant performance of the proposed method.
Do Teacher Reports of Executive Functions Predict Reading Development? Evidence from a Nationally Representative Sample
Authors: Weaver Andrew 
Published: August 2023

AbstractThis study explores whether teacher reports of executive functions predict change in reading performance (i.e., reading development) for elementary‐aged students when controlling for direct assessments of executive functions and for teacher reports of students' literacy skills. Prior research has raised problems with the construct validity of teacher reports of executive functions but has yet to consider that these teacher reports might be related to teachers' perceptions of their students' literacy skills. The current study used Grades 3 through 5 data from nationally representative data (N = 6945) of students collected between 2014 and 2016 to examine the contributions of teacher reports of executive functions to change in reading performance over the course of a year with autoregressive structural equation models. Measures of executive functions tapped attentional focusing (in Grades 3 and 4), working memory (in Grade 3), and inhibitory control (in Grade 4). When controlling for a direct assessment of the same facet of executive function as the teacher report, the teacher report of executive function predicted next year's reading. However, controlling for a teacher report of students' literacy skills reduced the effect of teacher reports of executive functions to nearly 0 across models while not reducing the effect of direct assessments of executive functions. This finding held across student race and home language subgroups in multigroup analyses. Based on these findings, teacher reports of executive functions do not capture information about executive functions that predicts of reading development beyond the teachers' perceptions of their students' literacy skills. Further research is needed to determine how teacher reports of EF could be designed to capture EFs as applied to reading.
Rural household's willingness to pay for irrigation water use: An application of contingent valuation method, in the case of North Shewa zone, Ethiopia
Authors: Shenkute Biruk Kemaw , Getahun Yitea Seneshaw , Moges Alebachew Shumye , Tesfaye Mekonnen Aklilu 
Published: August 2023

AbstractThis study aimed to evaluate household's willingness to pay (WTOP) for irrigation water use (IWU) per timad (0.25 ha) of the irrigable land per year and to analyze determinants of WTOP for IWU at individual households based on the contingent valuation method (CVM). The primary data collected for this study was from 120 households using two‐stage sampling techniques such as simple random sampling and purposive from four peasant associations of the Efratana Gidim and Kewit districts by semistructured questionnaire. The secondary dataset was collected from several sources. The collected data were analyzed using descriptive, inferential, and Tobit econometric models. In addition, a seemingly unrelated bivariate probit (SUBP) model was applied to calculate the average WTOP for IWU per timad/year. The CVM survey indicated that from the total sample collected data, 80% of the households showed WTOP for IWU, while the remaining 20% did not show WTOP. The econometric result of the Tobit model showed that the education level of the household, household family size, Irrigation experience, total annual income, and credit utilization influenced farmers' WTOP positively and significantly, while only initial bid price affected the farmer negatively and significantly. Hence, the above variables should be given high emphasis in designing irrigation water‐related projects in the districts. The SUBP model result revealed that the household's average annual WTOP was 854.74 Ethiopia Birr/0.25 ha/year. The estimated MWTOP for IWU is a huge amount of money. Hence, the concerned body has to collect money from households, which has to be used in the development of irrigation systems in the study area. This study recommends that different stakeholders of government should collaborate in raising revenue from the local community and apply it for the desired community development purposes, particularly for food security enhancement as the districts are highly dependent on rainfed agriculture.
Recasting bounds on long-lived heavy neutral leptons in terms of a light supersymmetric R-parity violating neutralino
Authors: Dreiner Herbi K. , Köhler Dominik , Nangia Saurabh , Schürmann Martin , Wang Zeren Simon 
Published: August 2023

Abstract
In R-parity-violating (RPV) supersymmetric models, light neutralinos with masses from the GeV-scale down to even zero are still allowed by all laboratory constraints. They are further consistent with dark matter observations, as they decay via RPV couplings. These RPV couplings are in general constrained to be small. Hence, such light neutralinos, if produced, e.g., at a beam-dump or collider experiment, appear as displaced vertices or missing energy at the detector level. The same signatures have been extensively searched for at various experiments in the theoretical context of sterile neutrinos which mix with active neutrinos. In this work, we recast the sensitivity of both past and present experiments to sterile neutrinos to obtain new bounds on RPV couplings associated with a light neutralino. We find experiments such as T2K, BEBC, FASER, DUNE, and MoEDAL-MAPP can improve the current bounds on RPV couplings by up to 3–4 orders of magnitude in several benchmark scenarios.
Holographic n-partite information in hyperscaling violating geometry
Authors: Ju Xin-Xiang , Lai Teng-Zhou , Sun Ya-Wen , Wang Yuan-Tai 
Published: August 2023

Abstract
The n-partite information (nI) is formulated as a measure of multi-partite entanglement. Field theory computation revealed that the sign of nI is indefinite for n ≥ 3, while holographic studies conjectured a sign property that holographic nI is non-negative/non-positive for even/odd n, with tripartite information (TI, n = 3) proved. We investigate the aspects of nI with holographic duality in hyperscaling violating geometry. We confirm the conjectured sign property for strips of equal length with equal separation distance, and disprove this conjecture for n > 3 with general configurations. Therefore, nI in field theories and holography exhibits compatibility except for n = 3. We also discuss other properties of holographic nI with analytic computation: the monotonicity, linearity, relation to hyperscaling violating parameters, temperature and UV cutoff effects, and the physical implications. It is doubtful that nI is an effective measure of entanglement considering the indefinite sign, non-monotonicity, and quasi-linearity of its holographic dual. In this respect, we propose constraints on the multi-partite entanglement measures.
A post-Gaussian approach to dipole symmetries and interacting fractons
Authors: Molina-Vilaplana J. 
Published: August 2023

Abstract
We use a post-Gaussian variational approach to non-perturbatively study a general class of interacting bosonic quantum field theories with generalized dipole symmetries and fractonic behavior. We find that while a Gaussian approach allows to carry out a consistent renormalization group (RG) flow analysis of these theories, this only grasps the interaction terms associated with the longitudinal motion of dipoles, which is consistent with previous analysis using large N techniques. Remarkably, our post-Gaussian proposal, by providing a variational improved effective potential, can capture the transverse part of the interaction between dipoles in such a way that a non-trivial RG flow for this term is obtained and analyzed. Our results suggest that dipole symmetries that manifest due to the strong coupling of dipoles, may robustly emerge at low energies from short-distance models without that symmetry.
Dark photon dark matter from cosmic strings and gravitational wave background
Authors: Kitajima Naoya , Nakayama Kazunori 
Published: August 2023

Abstract
Dark photon dark matter may be produced by the cosmic strings in association with the dark U(1) gauge symmetry breaking. We perform three-dimensional lattice simulations of the Abelian-Higgs model and follow the evolution of cosmic strings. In particular, we simulate the case of (very) light vector boson and find that such vector bosons are efficiently produced by the collapse of small loops while the production is inefficient in the case of heavy vector boson. We calculate the spectrum of the gravitational wave background produced by the cosmic string loops for the light vector boson case and find characteristic features in the spectrum, which can serve as a probe of the dark photon dark matter scenario. In particular, we find that the current ground-based detectors may be sensitive to such gravitational wave signals and also on-going/future pulsar timing observations give stringent constraint on the dark photon dark matter scenario.
Quantum error correction from complexity in Brownian SYK
Authors: Balasubramanian Vijay , Kar Arjun , Li Cathy , Parrikar Onkar , Rajgadia Harshit 
Published: August 2023

Abstract
We study the robustness of quantum error correction in a one-parameter ensemble of codes generated by the Brownian SYK model, where the parameter quantifies the encoding complexity. The robustness of error correction by a quantum code is upper bounded by the “mutual purity” of a certain entangled state between the code subspace and environment in the isometric extension of the error channel, where the mutual purity of a density matrix ρAB is the difference $$ {\mathcal{F}}_{\rho}\left(A:B\right)\equiv \textrm{Tr}\ {\rho}_{AB}^2-\textrm{Tr}\ {\rho}_A^2\ \textrm{Tr}\ {\rho}_B^2 $$

F
ρ

A
:
B

≡
Tr

ρ
AB
2

−
Tr

ρ
A
2

Tr

ρ
B
2

. We show that when the encoding complexity is small, the mutual purity is O(1) for the erasure of a small number of qubits (i.e., the encoding is fragile). However, this quantity decays exponentially, becoming O(1/N) for O(log N) encoding complexity. Further, at polynomial encoding complexity, the mutual purity saturates to a plateau of O(e−N). We also find a hierarchy of complexity scales associated to a tower of subleading contributions to the mutual purity that quantitatively, but not qualitatively, adjust our error correction bound as encoding complexity increases. In the AdS/CFT context, our results suggest that any portion of the entanglement wedge of a general boundary subregion A with sufficiently high encoding complexity is robustly protected against low-rank errors acting on A with no prior access to the encoding map. From the bulk point of view, we expect such bulk degrees of freedom to be causally inaccessible from the region A despite being encoded in it.
On the brane expansion of the Schur index
Authors: Beccaria M. , Cabo-Bizet A. 
Published: August 2023

Abstract
We consider the Schur index of $$ \mathcal{N} $$
N
= 4 U(N) SYM theory in 4d and its holographic giant graviton-type expansion at finite N. We compute the world-volume brane superconformal index by a recently proposed definition of the gauge holonomy integral as a multivariate residue. This is evaluated by a novel deformation algorithm that avoids Gröbner basis methods. Various terms of the brane expansion are computed and their sum is shown to be free of wall-crossing singularities to the order we explored. The relation between the brane expansion and previous giant graviton-type represenations of the Schur index is clarified.
Erweiterte präoperative sprachaudiometrische Diagnostik im Rahmen der Cochleaimplantatversorgung
Authors: Beyer Annika , Rieck Jan-Henrik , Mewes Alexander , Dambon Jan Andreas , Hey Matthias 
Published: August 2023

Zusammenfassung
Hintergrund
Bei einer hochgradigen, bis an Taubheit grenzenden Schallempfindungsschwerhörigkeit ist das Cochleaimplantat (CI) die Therapie der Wahl. Für die Indikationsstellung zur Cochleaimplantation sind das präoperativ gemessene Freiburger Einsilberverstehen (EV) bei 65 dB SPL mit Hörgerät (HG) im Freifeld (EVHG65) und das maximale Einsilberverstehen ohne HG mit Kopfhörern (mEV) von entscheidender Bedeutung. Ziel dieser retrospektiven Studie war die Analyse des Zusammenhangs zwischen EV mit dem HG bei 80 dB SPL (EVHG80) und dem mEV. Dies ist eine Ergänzung zur Bestimmung des EVHG65 im Vergleich zum mEV und zum Reintonaudiogramm (4FPTA).

Material und Methodik
Im Rahmen dieser Studie wurde das EV mit und ohne HG bei 661 Ohren retrospektiv analysiert. Einschlusskriterium war die spätere Implantation mit einem CI.

Ergebnisse
Im Rahmen der präoperativen CI-Diagnostik ergibt sich ein mEV von 0 % bei 334 Ohren. Ebenso lag das EVHG65 bei 485 Ohren bzw. das EVHG80 bei 335 Ohren bei 0 %. Das EV mit HG verschlechterte sich mit zunehmendem 4FPTA für beide Prüfpegel, wobei der Effekt bei 80 dB SPL weniger stark ausgeprägt war als bei 65 dB SPL. Werden nur Ohren betrachtet, welche präoperativ ein mEV > 0 % hatten (n = 260), zeigt sich eine stärkere Übereinstimmung zwischen dem EVHG80 und dem mEV mit einer Differenz von (−4,0 ± 16,4 %) im Vergleich zum EVHG65 und dem mEV mit einer Differenz von (−18,3 ± 16,7 %). Es zeigt sich ein signifikanter Unterschied zwischen dem mEV und dem EVHG80 im Vergleich zum mEV und dem EVHG65.

Schlussfolgerung
Das EV mit HG zeigt bei einem Sprachpegel von 65 dB SPL oftmals nicht die nach Hilfsmittelrichtlinie und CI-Leitlinie geforderte Annäherung des EV an das mEV. Das EVHG80 zeigt eine bessere Deckung mit dem mEV als das EVHG65. Es ist in der klinischen Diagnostik sinnvoll, das Sprachverstehen mit HG ergänzend oberhalb von 65 dB SPL zu untersuchen.
Carl Arthur Kollmann: Urologe, Venerologe und Puppenspieler in Leipzig
Authors: Moll Friedrich H. 
Published: August 2023

ZusammenfassungWährend die Erinnerungskultur zu dem aus Dresden stammenden sächsischen Urologen Felix Martin Oberländer innerhalb der deutschen Urologie gut entwickelt ist und sein Name in einem seit 1997 gestifteten Preis der Deutschen Gesellschaft für Urologie e. V. weiter fortlebt, ist die Erinnerung und das Wissen um Felix-Arthur Kollmann aus Leipzig in der Urologie verlorengegangen. Die Erinnerung an ihn in seinem weiteren akademischen Betätigungsfeld, dem Puppenspiel und der Puppenspielforschung ist bis heute lebendig.
Mouse phenome database: curated data repository with interactive multi-population and multi-trait analyses
Authors: Bogue Molly A. , Ball Robyn L. , Walton David O. , Dunn Matthew H. , Kolishovski Georgi , Berger Alexander , Lamoureux Anna , Grubb Stephen C. , Gerring Matthew , Kim Matthew , Liang Hongping , Emerson Jake , Stearns Timothy , He Hao , Mukherjee Gaurab , Bluis John , Davis Sara , Desai Sejal , Sundberg Beth , Kadakkuzha Beena , Kunde-Ramamoorthy Govindarajan , Philip Vivek M. , Chesler Elissa J. 
Published: August 2023

AbstractThe Mouse Phenome Database continues to serve as a curated repository and analysis suite for measured attributes of members of diverse mouse populations. The repository includes annotation to community standard ontologies and guidelines, a database of allelic states for 657 mouse strains, a collection of protocols, and analysis tools for flexible, interactive, user directed analyses that increasingly integrates data across traits and populations. The database has grown from its initial focus on a standard set of inbred strains to include heterogeneous mouse populations such as the Diversity Outbred and mapping crosses and well as Collaborative Cross, Hybrid Mouse Diversity Panel, and recombinant inbred strains. Most recently the system has expanded to include data from the International Mouse Phenotyping Consortium. Collectively these data are accessible by API and provided with an interactive tool suite that enables users’ persistent selection, storage, and operation on collections of measures. The tool suite allows basic analyses, advanced functions with dynamic visualization including multi-population meta-analysis, multivariate outlier detection, trait pattern matching, correlation analyses and other functions. The data resources and analysis suite provide users a flexible environment in which to explore the basis of phenotypic variation in health and disease across the lifespan.
Clinical and neuroimaging characteristics in mild-type infantile acute subdural hematoma: report of four cases
Authors: Aoki Nobuhiko 
Published: August 2023

Abstract
Purpose
Infantile acute subdural hematoma (IASDH) has a limited age distribution and mostly benign clinical features. Mild-type IASDH has a stereotypical clinical course which, however, has been described in only a few studies.

Methods
Four male infants (aged 6–10 months; mean age: 7.5 months) were diagnosed as mild-type IASDH associated with retinal hemorrhage (RH) after suffering from occipital impact in a fall. The present case series reviews their clinical features and neuroimaging findings, including CT and MRI findings.

Results
All the infants fell backwards from a standing or sitting position onto a soft surface, striking the occipital region. They began crying on impact and then soon afterwards exhibited seizure-like activity or recurrent vomiting. CT and MRI revealed a thin, unclotted subdural hematoma (SDH) without mass effect or brain parenchymal abnormality. Various degrees of bilateral RH were observed. On the day of symptom onset, all infants returned to baseline, and follow-up more than 5 years revealed normal development with no deficits.

Conclusions
Mild-type IASDH with retinal hemorrhage presents with seizure-like activity or recurrent vomiting preceded by crying after an occipital impact on a soft surface. The clinical course of IASDH is followed by rapid recovery on the day of symptom onset. CT and MRI findings reveal a small, unclotted SDH without a mass effect or cerebral parenchymal abnormality.