bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in mental indicators and state-hope related to the level of engagement in social unrest in Israel
Authors: Hamama-Raz Yaira , Leshem Elazar , Ben-Ezra Menachem 
Published: July 2023

Abstract
Background
This study examined the interplay between engagement in social unrest, mental indicators, state-hope and demographic variables. In addition, mental indicators and state-hope were compared in line with levels of engagement in social unrest.
Methods
In a cross-sectional study, conducted from March 23 to April 10, 2023, 2015 Israelis were recruited via a survey company. Participants completed self-report questionnaires to assess engagement in social unrest, anxiety, social unrest related distress, state-hope and demographic variables.
Results
Participants with higher engagement in social unrest, who opposed the law reform, were prone to higher levels of social unrest related distress, anxiety, and lower levels of state-hope compared to those not engaged in social unrest activities or those who supported the law reform.
Conclusions
Concerns regarding unmet mental health needs, during and following social unrest, regardless of the engagement level, should be actively addressed by mental health professionals and health policy makers.
Structural behavior of pre-engineered buildings provided with different types of bracings in various seismic zones
Authors: Bharmal Pravin. P. , Kumbhar Popat. D. , Gumaste Krishnakedar. S. 
Published: July 2023

Abstract
In recent years, the use of Pre-engineered buildings (PEB) has become more popular due to their important advantages over conventional steel structures (CSB) such as cost-effectiveness, faster construction, low maintenance, consistent span, reasonable earthquake resistance, the capability of offering column-free area, etc. This paper focuses on the analytical study of the structural behavior of a PEB provided with different types of bracings (viz. X, V, K, and diagonal) considering all the seismic zones (i.e., II, III, IV, and V) and medium type of soil. The analysis of a PEB of size 22m x 44m is done using Staad Pro software considering wind and seismic forces for determining the efficient type of bracing that will minimize the structural responses viz. displacement and natural time period. The results of the study indicate that the PEB provided with diagonal bracing reduces displacement and natural time period by 13% and 15.80% respectively when compared with the corresponding average values of displacement and natural time period of PEBs provided with X, V, and K types of bracings. The study concludes that the provision of diagonal bracing contributes to improving the performance of PEB in all the seismic zones.
Clinical analysis of 116 children with Meckel’s diverticulum
Authors: Zhang TingTing , Zhang RuiYun , Cai Peng , Zhu Jie , Chen Jian Lei , Zhao Hao Wei , Jiang Yu Liang , Wang Qi , Zhu Meng Lei , Zhou Xiao Gang , Hu Fei Long , Gu Zhi Cheng , Zhu Zhen Wei 
Published: July 2023

Abstract
Objective: We aimed to retrospectively analyze the clinical characteristics of pediatric Meckel’s diverticulum to improve the understanding and diagnosis of Meckel’s diverticulum in children.
Methods: The clinical data of 116 hospitalized children with Meckel’s diverticulum diagnosed by surgery in the Department of Pediatric Surgery, Children’s Hospital of Soochow University, between January 2017 and January 2023 were analyzed retrospectively.
Results: A total of 95 boys and 21 girls were included in this study, with a male-to-female ratio of 4.524:1. The observed clinical manifestations could be roughly divided into the following three categories: gastrointestinal bleeding in 68 cases (59%), intestinal obstruction in 35 cases (30%), and abdominal inflammation in 10 cases (9%). The positive rate of 99TcmO4-ECT was higher than that of abdominal ultrasound in all patients and patients with gastrointestinal bleeding. The sensitivity and specificity of 99TcmO4-ECT were 98% and 25%, respectively. The surgical methods of Meckel’s diverticulum are mainly divided into two types: either wedge resection of the diverticulum or resection of the diverticulum and adjacent bowel after laparoscopic or open exploration. The average distance between the diverticulum and ileocecal junction was 50.5 ± 18.2 cm, the average length of the diverticulum was 3.25 ± 1.6 cm, and the average width of the diverticulum was 1.52 ± 0.7 cm. According to the pathological examination results, the incidence of ectopic mucosal tissue in Meckel’s diverticulum in the gastrointestinal bleeding group was higher than that in the non-gastrointestinal bleeding group. The clinical symptoms of gastrointestinal bleeding in children with Meckel’s diverticulum are related to the presence of ectopic mucosal tissue.
Conclusions: Gastrointestinal bleeding is the most common clinical manifestation of Meckel’s diverticulum in children, and it is closely related to the presence of ectopic mucosal tissue. 99TcmO4-ECT is an important imaging examination for the diagnosis of Meckel’s diverticulum. Once Meckel’s diverticulum is suspected, immediate surgical resection is advocated.
Fraunhofer Diffraction Patterns by Incorporating hBN
Authors: Lei Jin , Jiang Hua , Zhang Lee , Zhang Yan , Li Jingxiang 
Published: July 2023

Abstract
This research paper explores the intriguing world of Fraunhofer diffraction manipulation using Hexagonal Boron Nitride (hBN) as the diffracting material. Through a comprehensive theoretical investigation and MATLAB simulations, we analyze the diffraction patterns obtained for different incident light frequencies and phases. The diffraction patterns exhibit fascinating variations, showcasing hBN's tunable nature in controlling the spatial distribution of diffracted light. As the incident light frequency increases, the diffraction peaks shift to higher angles, reflecting hBN's dispersion characteristics. The energy intensity pattern also undergoes significant changes, with regions of higher intensity shifting as the frequency varies. The validated theoretical model and simulations emphasize hBN's potential as a versatile platform for diffractive optics and light manipulation, promising applications in advanced spectroscopy, optical communications, and nanophotonic devices. The insights gained from this study pave the way for harnessing hBN's optical properties in emerging quantum technologies and integrated photonics, driving innovations in the realm of optical control and light manipulation.
Mechanistic role of RND3-regulated IL33/ST2 signaling on cardiomyocyte senescence
Authors: Wu Linxu , Zhu Xinglin , Luo Cai , Zhao Yangyang , Pan Shanshan , Shi Kaijia , Shen Zhihua , Guo Junli , Jie Wei 
Published: July 2023

Abstract

BACKGROUND: Hyperinflammatory responses are pivotal in the pathophysiology of cardiomyocyte senescence, with IL33 serving as a crucial pro-inflammatory mediator. Our previous findings highlighted RND3's suppressive effect on IL33 expression. This study delves into the influence of RND3 on IL33/ST2 signaling activation and cardiomyocyte senescence.
METHODS: AC16 cardiomyocytes were subjected to treatments involving recombinant IL33, NF-κB inhibitor PDTC, or ST2 antibody Astegolimab. SA-β-gal and γH2AX staining were utilized to monitor alterations in cell senescence and DNA damage, respectively. Western blot analysis was conducted to ascertain the expression of Senescence-Associated Secretory Phenotype (SASP) and NF-κB activation. Utilizing CRISPR/Cas9 technology, the RND3 gene was knocked out in H9C2 cells, followed by senescence analysis and sST2 level detection in the culture medium supernatant via ELISA. Post-AAV9 injection overexpressing RND3 in SD rats, IL33/ST2 and SASP expression in heart tissues, and serum IL33 and sST2 changes were evaluated using ELISA.
RESULTS: Exogenous IL-33 significantly induced IL-1α, IL6, and MCP1 expression, increased the p-p65/p65 ratio, and the proportion of SA-β-gal and γH2AX positive cells in AC16 cells. PDTC and Astegolimab application mitigated these effects. RND3 knockout in H9C2 cells led to increased intracellular IL33, ST2L, IL1 α, IL6, and MCP1 expression, decreased sST2 in the supernatant, and increased SA-β-gal and γH2AX positive cells. RND3 overexpression suppressed IL33, ST2L, IL-1α, IL6, and MCP1 expression in heart tissues, decreased serum IL33, and increased sST2 levels.
CONCLUSION: RND3 expression in cardiomyocytes modulates cell senescence by negatively regulating the IL33/ST2/NF-κB signaling pathway, underscoring its potential as a therapeutic target in cardiovascular senescence.
Association between sedentary behavior and physical activity with arthritis in the NHANES 2007-2016
Authors: Ji Hongshen , Li Lei , Zhang Wenfeng , Chen Xing , Sun Jian , Xie Hezhi , Xu Kun 
Published: July 2023

Abstract
Background
Arthritis stands as a major, globally rampant, and enduring health condition. Influences such as age, hereditary factors, and excessive body weight have been understood to trigger arthritis, yet the impact of physical activity and a sedentary behavior remains less explored. The objective of this research is to ascertain the linkage between physical activity, sedentary behavior, and arthritis manifestation.
Methods
We harnessed data from the representative National Health and Nutrition Examination Survey (NHANES) spanning 2007 to 2016. A multivariate logistic regression model was adopted to assess the correlation between physical activity, sedentary behavior, and arthritis, and to present the odds ratios (OR).
Results
Arthritis prevalence was notably higher among females, the elderly, non-Hispanic white demographic, moderate alcohol consumers, smokers, individuals with obesity, and diabetic patients. Total physical activity, heightened transportation and leisure-time physical activity, and diminished sedentary behavior corresponded with a lower arthritis onset. The adjusted multivariate regression analysis unveiled individuals lacking occupational moderate-to-vigorous physical activity (MVPA) showed decreased odds of arthritis (OR = 0.71, 95% CI = 0.62–0.81, p < 0.01). Furthermore, individuals demonstrating high sedentary behavior during non-screen time had increased odds of arthritis (OR = 1.25, 95% CI = 1.1–1.41, p < 0.01).
Conclusion
Physical activity is integral to joint health, with active individuals indicating lower arthritis onset, while prolonged stationary behavior was linked to increased arthritis cases. Hence, endorsing moderate physical activity and curtailing sedentary periods emerge as crucial strategies for arthritis prevention and control.
On the Automatic Continuity on Fréchet algebras
Authors: Mustapha LAAYOUNI 
Published: July 2023

Abstract
A topological algebra A over C is called functionally continuous if each complex homomorphism on A is continuous. It is well-known that each Banach algebra is functionally continuous, but it is not known whether or not each commutative Fréchet algebra has this property; This is a famous question called Michael’s problem. Many mathematicians have been trying to answer this old problem in the past 70 years. To give an affirmative answer to this conjecture we use two great theorems of functional analysis, namely the closed graph theorem and the open image theorem: Let φ be complex homomorphism on a commutative Fréchet al- gebra (A; (|| ||n)n≥0 ). Our first result shows that there exists an integer q such that ker (|| ||q) ⊂ ker (φ) (Theorem 2.1). Next, we will provide A with a sequence (||.||′ n)n of semi-norms under which A is a Fréchet algebra (Lemma2.2 ) and which make the character φ continuous. The Closed graph theorem [2 , B.2, p.335] and the open image theorem [2, B.1, p.335 ] allow us to show that the two topologies are equivalent on A (Lemma2.3) and therefore φ is (|| ||n)n-continuous (Theorem2.3)
Financial Development- International Trade Nexus in Ghana: The Role of Sectoral Effects
Authors: Prempeh Kwadwo Boateng , Frimpong Joseph Magnus 
Published: July 2023

Abstract

This study investigates the role of sectoral effects in the finance-trade nexus using time series data from Ghana from 1960 to 2017. Our evidence from the autoregressive distributed lag (ARDL) estimates indicates that while the effect of sectoral value additions on trade is conditional on the proxy of finance, financial development significantly promotes trade in both the long and short run regardless of the proxy. Moreover, even after accounting for sectoral value additions, finance had a positive effect on trade. On the moderation front, we observe that increased agricultural value additions mitigate the beneficial impact of finance on trade, whereas increased service value additions magnify the beneficial effects. Thus, to boost international trade in Ghana, policymakers should prioritise fostering complementarity between the industrial, agricultural, service, manufacturing, and financial sectors.
Jel Classification: F13; F14; G21
Comparing Radiopacity of Nanohybrid Composite and Giomers: An In Vitro Study
Authors: Vyas Aarshati , Shah Shilpa , Patel Nishtha , Yagnik Krushnangi , Yagnik Kruti 
Published: July 2023

Aim: The aim of this study was to evaluate and compare the radiopacity of three different composite resins; one nanohybrid and two giomers.
Material and Methods:
For evaluation of radiopacity of composites, ten specimens of each material [(3 groups) (total 30) (n=10] with thicknesses of 2 mm were prepared and radiographed alongside aluminum step wedge and human enamel and dentin. Occlusal radiograph was taken and mean gray values of the test materials were measured using Image J software. Then a conversion was performed to establish the radiopacity of the test materials, in millimeters of equivalent Aluminum (Al). Data were analyzed using one‑way analysis of variance and Scheffe’s Post Hoc tests (P < 0.05).
Results:
The radiopacity values varied among the restorative materials (p < 0.05) with the highest for Filtek followed by Beautifil Injectable, Beautifil 2, enamel and dentin.

Conclusion:
All materials tested had radiopacity values greater than dentin and had sufficient radiopacity to meet International Organization for Standardization 4049 standard.

Key Words: Radiopacity, aluminum stepwedge, composites, opacifing-fillers.
Non-coding RNAs in Regulation of Protein Aggregation and Clearance
Pathways: Current Perspectives Towards Alzheimer's Research and
Therapy
Authors: Sundram Sonali , Dhiman Neerupma , Malviya Rishabha , Awasthi Rajendra 
Published: July 2023

Abstract:
Alzheimer's disease (AD) is the leading cause of dementia, affecting approximately 45.0
million people worldwide and ranking as the fifth leading cause of mortality. AD is identified by neurofibrillary
tangles (NFTs), which include abnormally phosphorylated tau-protein and amyloid protein
(amyloid plaques). Peptide dysregulation is caused by an imbalance between the production and clearance
of the amyloid-beta (Aβ) and NFT. AD begins to develop when these peptides are not cleared
from the body. As a result, understanding the processes that control both normal and pathological protein
recycling in neuronal cells is critical. Insufficient Aβ and NFT clearance are important factors in
the development of AD. Autophagy, lysosomal dysfunction, and ubiquitin-proteasome dysfunction
have potential roles in the pathogenesis of many neurodegenerative disorders, particularly in AD.
Modulation of these pathways may provide a novel treatment strategy for AD. Non-coding RNAs
(ncRNAs) have recently emerged as important biological regulators, with particular relevance to the
emergence and development of neurodegenerative disorders such as AD. ncRNAs can be used as potential
therapeutic targets and diagnostic biomarkers due to their critical regulatory functions in several
biological processes involved in disease development, such as the aggregation and accumulation of
Aβ and NFT. It is evident that ncRNAs play a role in the pathophysiology of AD. In this communication,
we explored the link between ncRNAs and AD and their regulatory mechanisms that may help in
finding new therapeutic targets and AD medications.
Preparation and Characterization of Nickle-based Nanocatalyst for the
Regioselective Synthesis Triazole Derivatives and Antimicrobial Study
Authors: Heidari Nadia , Albadi Jalal , Hemmati Zahra , Jalali Mehdi 
Published: July 2023

Abstract:
In this research, poly (4-vinyl pyridine)-supported nickel oxide nanoparticles (P4VP-NiO
nanocatalyst) as an efficient recyclable catalyst have been prepared and used for the regioselective
synthesis of triazole derivatives. The nanocatalyst we characterized by Fourier-transform infrared
spectroscopy (FT-IR), field emission scanning electron microscopy (FESEM), energy dispersive spectroscopy
(EDS), x-ray diffraction (XRD), thermogravimetric analysis (TGA), inductively coupled
plasma (ICP), and brunauer-emmett-teller (BET) surface area analysis. The most important advantages
of using poly (4-vinylpyridine)-nickel oxide nanocatalysts in these reactions are the short reaction
time, cost-effectiveness, easy recycling of the catalyst, and high yield of the product. Also, the
antimicrobial properties of the new triazole derivatives have been studied.
Return to work following traumatic brain injury: An exploration of using the Brannagan Executive Functions Assessment to increase self-awareness in practice
Authors: Mason Fiona , George Stacey , Pryor Julie 
Published: July 2023

Aim and Background: The Brannagan Executive Functions Assessment is an occupation-based approach for increasing self-awareness. This study explores the application of the Brannagan Executive Functions Assessment in traumatic brain injury return to work intervention. It describes changes in self-awareness, goal achievement and perspectives of occupational therapy and people with brain injury. Methods: Case study design using a mixed-methods approach: with pre-post evaluation of outcomes and semi-structured interviews. Participants with traumatic brain injury completed the assessment with two occupational tasks related to return to work. Primary outcomes were self-awareness (Self-awareness Deficits Interview and Awareness Questionnaire) and Goal performance/satisfaction using the Canadian Occupational Performance Measure. Mood was a secondary outcome. Analysis was descriptive for quantitative data, thematic for qualitative data. Results: Two participants with brain injury, two support people and one occupational therapist were recruited. One participant with brain injury had an increase in self-awareness scores. Brain injury participants and the occupational therapist identified benefits including an increased awareness of needing to incorporate planning to meet goals. Conclusion: The Brannagan Executive Functions Assessment offers benefits to practice in brain injury rehabilitation, facilitating a structured occupational approach to self-awareness and participation in meaningful return to work tasks.
Internet-Based Recruitment and Retention of Young Adults With Type 1 Diabetes: Cross-Sectional Study
Authors: Griggs Stephanie , Ash Garrett I , Pignatiello Grant , Papik AnnMarie , Huynh Johnathan , Leuchtag Mary , Hickman Jr Ronald L 
Published: July 2023

Background
Multiple research strategies are required to recruit and engage a representative cohort of young adults in diabetes research. In this report, we describe an approach for internet-based recruitment for a repeated-measures descriptive study.

Objective
The objective of this cross-sectional study was to determine whether internet-based recruitment through multiple social media platforms, a clinical research platform, and cooperation with community partnerships—College Diabetes Network and Beyond Type 1—would serve as an effective way to recruit a representative sample of young adults aged 18-25 years with type 1 diabetes (T1D).

Methods
We conducted a repeated-measures descriptive study. We captured enrollment rates and participant characteristics acquired from each social media platform through survey data and Facebook analytics. This study was advertised via paid postings across a combination of different social media platforms (eg, Facebook, Instagram, Twitter, and Reddit). We used quarterly application postings, quarterly newsletters, and participation in the ResearchMatch registry to identify potentially eligible participants from February 3, 2021, to June 6, 2022.

Results
ResearchMatch proved to be the most cost-effective strategy overall, yielding the highest gender and racial diversity compared to other internet platforms (eg, Facebook, Instagram, Twitter, and Reddit), application postings (eg, Beyond Type 1), and newsletters (eg, College Diabetes Network and a local area college). However, we propose that the combination of these approaches yielded a larger, more diverse sample compared to any individual strategy. Our recruitment cost was US $16.69 per eligible participant, with a 1.27% conversion rate and a 30% eligibility rate.

Conclusions
Recruiting young adults with T1D across multiple internet-based platforms was an effective strategy to yield a moderately diverse sample. Leveraging various recruitment strategies is necessary to produce a representative sample of young adults with T1D. As the internet becomes a larger forum for study recruitment, participants from underrepresented backgrounds may continue engaging in research through advertisements on the internet and other internet-based recruitment platforms.
Assessing ChatGPT’s Capability for Multiple Choice Questions Using RaschOnline: Observational Study
Authors: Chow Julie Chi , Cheng Teng Yun , Chien Tsair-Wei , Chou Willy 
Published: July 2023

Background
ChatGPT (OpenAI), a state-of-the-art large language model, has exhibited remarkable performance in various specialized applications. Despite the growing popularity and efficacy of artificial intelligence, there is a scarcity of studies that assess ChatGPT’s competence in addressing multiple-choice questions (MCQs) using KIDMAP of Rasch analysis—a website tool used to evaluate ChatGPT’s performance in MCQ answering.

Objective
This study aims to (1) showcase the utility of the website (Rasch analysis, specifically RaschOnline), and (2) determine the grade achieved by ChatGPT when compared to a normal sample.

Methods
The capability of ChatGPT was evaluated using 10 items from the English tests conducted for Taiwan college entrance examinations in 2023. Under a Rasch model, 300 simulated students with normal distributions were simulated to compete with ChatGPT’s responses. RaschOnline was used to generate 5 visual presentations, including item difficulties, differential item functioning, item characteristic curve, Wright map, and KIDMAP, to address the research objectives.

Results
The findings revealed the following: (1) the difficulty of the 10 items increased in a monotonous pattern from easier to harder, represented by logits (–2.43, –1.78, –1.48, –0.64, –0.1, 0.33, 0.59, 1.34, 1.7, and 2.47); (2) evidence of differential item functioning was observed between gender groups for item 5 (P=.04); (3) item 5 displayed a good fit to the Rasch model (P=.61); (4) all items demonstrated a satisfactory fit to the Rasch model, indicated by Infit mean square errors below the threshold of 1.5; (5) no significant difference was found in the measures obtained between gender groups (P=.83); (6) a significant difference was observed among ability grades (P<.001); and (7) ChatGPT’s capability was graded as A, surpassing grades B to E.

Conclusions
By using RaschOnline, this study provides evidence that ChatGPT possesses the ability to achieve a grade A when compared to a normal sample. It exhibits excellent proficiency in answering MCQs from the English tests conducted in 2023 for the Taiwan college entrance examinations.