bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of international students on housing markets
Authors: Mocanu Tatiana , Tremacoldi‐Rossi Pedro 
Published: March 2023

AbstractWe study the impact of the 2005–2015 international student boom in US universities on local housing markets. By constructing a sample of American college towns characterizing rarely studied local markets in small urban areas, we show that international students exogenously sustained demand for rentals and residential investment, representing counter‐cyclical shocks during the Great Recession. Exploiting the historical distribution of foreign enrolment across college towns and country‐of‐origin networks, we find that international students increased rents by 1.3% and home prices by 2.5% relative to the housing boom peak, translating into home equity gains of $4,000. An analysis exploiting within‐city dynamics reveals that neighbourhoods near campus absorbed international inflows by replacing single‐family homes with apartment rentals.
Implications for biological invasion of non‐native plants for sale in the world's largest online market
Authors: Banerjee Achyut Kumar , Lee Tien Ming , Feng Hui , Liang Xinru , Lin Yuting , Wang Jiakai , Yin Minghui , Peng Hao , Huang Yelin 
Published: March 2023

AbstractInternet trade is increasingly recognized as a dispersal pathway of non‐native plant species that is difficult to monitor. We sought to identify non‐native flora present in the Chinese online market, the largest e‐commerce market globally, and to decipher the effect of existing trade regulations, among other variables, on e‐trading patterns and to inform policy. We used a comprehensive list of 811 non‐native plant species in China present in 1 of the 3 phases of the invasion continuum (i.e., introduced, naturalized, and invasive). The price, propagule types, and quantities of the species offered for sale were retrieved from 9 online stores, including 2 of the largest platforms. Over 30% of the non‐native species were offered for sale in the online marketplaces; invasive non‐native species dominated the list (45.53%). No significant price difference was observed across the non‐native species of the 3 invasion categories. Among the 5 propagule types, a significantly higher number of non‐native species were offered for sale as seeds. The regression models and path analyses consistently revealed a direct positive effect of the number of uses and species’ minimum residence time and an indirect effect of biogeography on the pattern of trade in non‐native plant species when minimal phylogenetic signal was detected. A review of the existing phytosanitary regulations in China revealed their inadequacy in managing e‐trading of non‐native plant species. To address the problem, we propose integration of a standardized risk assessment framework that considers perceptions of stakeholders and is adaptable based on continuous surveillance of the trade network. If implemented successfully, the measures could provide a template for other countries to strengthen trading regulations for non‐native plant species and take proactive management measures.
Estimating the value of sodium‐glucose cotransporter‐2 inhibitors within the context of contemporary guidelines and the totality of evidence
Authors: McEwan Phil , Foos Volker , Martin Becky , Chen Jieling , Evans Marc 
Published: March 2023

AbstractAimsTo comprehensively estimate the cost‐effectiveness of sodium glucose cotransporter‐2 (SGLT2) inhibitor usage in the management of type 2 diabetes mellitus (T2DM) at established clinical review points, incorporating the totality of proven health benefits.Materials and methodsThis study considered the cardio‐ and reno‐protective effects of SGLT2 inhibitors using the Cardiff type 2 diabetes model. Conventional cost‐effectiveness evaluations were undertaken for eligible populations at relevant intensification points reflecting the 2022 guidelines versus the 2015 National Institute of Health and Care Excellence (NICE) guidelines; incremental cost‐effectiveness ratio lifetime trajectories and timepoints for complete cost‐offset were estimated for each pathway. Treatment effects, utility decrements and costs (applied additively and discounted at 3.5%) were sourced from the published literature.ResultsFor all subpopulations on treatment pathways reflecting the NG28‐2022 guidelines, SGLT2 inhibitor introduction was cost‐effective, becoming cost‐saving between 2 and 16 years post‐initiation. Despite increases in pharmacy costs, predicted lifetime costs were lower than for pathways reflecting the NG28‐2015 guidelines, driven by a reduction in heart failure hospitalization and chronic kidney disease costs. Incremental gains in quality‐adjusted life years (ranging from 0.58–1.12) resulted in dominance for the updated NG28‐2022 guidance in all scenarios.ConclusionsOur results show that SGLT2 inhibitors have the potential to lower healthcare costs while improving health outcomes in eligible patient subpopulations.
Can motor proficiency testing predict sports injuries and sports‐induced bleeds in people with haemophilia?
Authors: Versloot Olav , Blokzijl Johan , Timmer Merel , Schuuring Marleen , van Galen Karin , Kremer Hovinga Idske , van der Valk Paul , van Vulpen Lize , Schutgens Roger , van Koppenhagen Casper , van der Net Janjaap , Fischer Kathelijn 
Published: March 2023

AbstractIntroductionPredicting the risk of sports injuries and sports‐induced bleeds (SIBs) in people with haemophilia (PWH) may support clinical counselling.AimTo assess the association between motor proficiency testing and sports injuries and SIBs and to identify a specific set of tests for predicting injury risk in PWH.MethodsIn a single centre, prospective study male PWH aged 6–49 playing sports ≥1x/week were tested for running speed and agility, balance, strength and endurance. Test results below −2Z were considered poor. Sports injuries and SIBs were collected for 12 months while 7 days of physical activity (PA) for each season was registered with accelerometers. Injury risk was analysed according to test results and type of physical activity (%time walking, cycling, running). Predictive values for sports injuries and SIBs were determined.ResultsData from 125 PWH (mean [± SD] age: 25 [± 12], 90% haemophilia A; 48% severe, 95% on prophylaxis, median factor level: 2.5 [IQR 0–15]IU/dl) were included. Few participants (n = 19, 15%) had poor scores. Eighty‐seven sports injuries and 26 SIBs were reported. Poor scoring participants reported 11/87 sports injuries and 5/26 SIBs. The current tests were poor predictors of sports injuries (Range PPV: 0%–40%), or SIBs (PPV: 0%–20%). PA type was not associated with season (activity seasonal p values > .20) and type of PA was not associated with sports injuries or SIBs (Spearman's rho < .15).ConclusionThese motor proficiency‐ and endurance tests were unable to predict sports injuries or SIBs in PWH, potentially due to few PWH with poor results and low numbers of sports injuries and SIBs.
Health‐related quality of life in persons with haemophilia in Afghanistan
Authors: Hosseini Sayed Mohammad Reza , Mousavi Sayed Hamid , Mesbah‐Namin Seyed Alireza , Tabibian Shadi , Dorgalaleh Akbar 
Published: March 2023

AbstractIntroductionHaemophilia is the most common severe congenital bleeding disorder and can significantly influence patients’ quality of life. The health‐related quality of life (HRQoL) is a multi‐dimensional concept that assess effect of different aspects of health status, including physical, mental, and social domains. Identification of the factors affecting the HRQoL of Persons with Haemophilia (PWH) can guide health care system to better management of patients.AimThe aim of the present study is to evaluate HRQoL in PWH in Afghanistan.MethodsThis cross‐sectional study was conducted on 100 PWH in Kabul City, Afghanistan. Data were collected using 36‐Item‐Short‐Form Health Survey (SF‐36) questionnaire and analysed using correlation coefficients and regression analysis.ResultsThe mean scores for the SF‐36 questionnaire 8 domains range from 33 ± 38.3 to 58.15 ± 20.5. The highest mean value belongs to physical function (PF) (58.15), whereas the lowest is related to restriction of activities due to emotional problems (RE) (33.00). A significant association (p < .005) was observed between all domains of SF‐36 and patients’ age except for PF (p = .055) and general health (GH) (p = .75). A significant association was also observed between all HRQoL domains and the severity of haemophilia (p < .001). The severity of haemophilia was the significant predictor for Physical Component Summary (PCS) and Mental Component Summary (MCS) (p < .001).ConclusionDue to the reduced HRQoL in Afghan PWH, special attention by health care system should be paid to improve patients’ quality of life.
Dermoscopic approach for differential diagnosing of autoimmune bullous disease: pemphigus vulgaris, pemphigus foliaceus, and IgA pemphigus
Authors: Gharib Khaled , Nassar Amani , Youssef Ayman , Bessar Hagar 
Published: March 2023

AbstractIntroductionDermoscopy is a noninvasive technique for the evaluation of different pigments and microstructures of the epidermis, dermoepidermal junction, and papillary dermis that are not apparent to the naked eye, which therefore improves diagnostic accuracy.Aim of the studyThis study aims to describe the characteristic dermoscopic features of bullous diseases and analyze the characteristic dermoscopic features of bullous diseases of the skin and hair.Patients and methodsA descriptive study was conducted to describe and analyze the characteristic dermoscopic features of bullous diseases in the Zagazig University Hospitals.ResultsThis study enrolled 22 patients. Dermoscopy revealed yellow hemorrhagic crusts in all patients and white yellow structure with red halo in 90.9% of patients. Pemphigus vulgaris patients were identified by the presence of dermoscopic clues such as bluish deep discoloration, tubular scaling, black dots, hair casts, hair tufts, yellow dots with whitish halos (fried egg sign) and yellow follicular pustules that are not seen in pemphigus foliaceus and IgA pemphigus.DiscussionDermoscopy is an important tool that serves as a link between clinical and histopathological diagnoses, and it can easily be used in daily practice. Several suggestive dermoscopic features can help in the differential diagnosis of autoimmune bullous disease but only after making a provisional clinical diagnosis. Dermoscopy is a very useful tool in the differentiation of pemphigus subtypes.
Bacterial and viral infections among adults hospitalized with COVID‐19, COVID‐NET, 14 states, March 2020–April 2022
Authors: Shah Melisa M. , Patel Kadam , Milucky Jennifer , Taylor Christopher A. , Reingold Arthur , Armistead Isaac , Meek James , Anderson Evan J. , Weigel Andy , Reeg Libby , Como‐Sabetti Kathryn , Ropp Susan L. , Muse Alison , Bushey Sophrena , Shiltz Eli , Sutton Melissa , Talbot H. Keipp , Chatelain Ryan , Havers Fiona P. ,   the CDC COVID‐NET Surveillance Team
Published: March 2023

AbstractBackgroundBacterial and viral infections can occur with SARS‐CoV‐2 infection, but prevalence, risk factors, and associated clinical outcomes are not fully understood.MethodsWe used the Coronavirus Disease 2019‐Associated Hospitalization Surveillance Network (COVID‐NET), a population‐based surveillance system, to investigate the occurrence of bacterial and viral infections among hospitalized adults with laboratory‐confirmed SARS‐CoV‐2 infection between March 2020 and April 2022. Clinician‐driven testing for bacterial pathogens from sputum, deep respiratory, and sterile sites were included. The demographic and clinical features of those with and without bacterial infections were compared. We also describe the prevalence of viral pathogens including respiratory syncytial virus, rhinovirus/enterovirus, influenza, adenovirus, human metapneumovirus, parainfluenza viruses, and non‐SARS‐CoV‐2 endemic coronaviruses.ResultsAmong 36 490 hospitalized adults with COVID‐19, 53.3% had bacterial cultures taken within 7 days of admission and 6.0% of these had a clinically relevant bacterial pathogen. After adjustment for demographic factors and co‐morbidities, bacterial infections in patients with COVID‐19 within 7 days of admission were associated with an adjusted relative risk of death 2.3 times that of patients with negative bacterial testing. Staphylococcus aureus and Gram‐negative rods were the most frequently isolated bacterial pathogens. Among hospitalized adults with COVID‐19, 2766 (7.6%) were tested for seven virus groups. A non‐SARS‐CoV‐2 virus was identified in 0.9% of tested patients.ConclusionsAmong patients with clinician‐driven testing, 6.0% of adults hospitalized with COVID‐19 were identified to have bacterial coinfections and 0.9% were identified to have viral coinfections; identification of a bacterial coinfection within 7 days of admission was associated with increased mortality.
Examining shifts in conceptual knowledge, procedural knowledge and procedural flexibility in the context of two game‐based technologies
Authors: Chan Jenny Yun‐Chen , Closser Avery H. , Ngo Vy , Smith Hannah , Liu Allison S. , Ottmar Erin 
Published: March 2023

AbstractBackgroundPrior work has shown that middle school students struggle with algebra and that game‐based educational technologies, such as DragonBox and From Here to There!, are effective at improving students' algebraic performance. However, it remains unclear which aspects of algebraic knowledge shift as a result of playing these games and what game design features support algebraic learning.ObjectiveUsing the data from a randomized controlled trial conducted in the 2020–2021 academic year, we (a) examined students' relative performance on assessment items measuring conceptual knowledge, procedural knowledge and procedural flexibility in algebraic equation solving, and (b) identified changes in these aspects of algebraic knowledge after playing DragonBox or From Here to There!.MethodsEight hundred eighty‐seven seventh‐graders were randomly assigned to playing DragonBox or From Here to There! for nine 30‐min sessions throughout the school year. Students also completed a pretest, midtest and posttest measuring their algebraic knowledge.Results and ConclusionFirst, prior to the intervention, students scored the highest on procedural knowledge and lowest on conceptual knowledge. Second, students significantly improved and maintained learning gains on conceptual knowledge throughout the intervention. Their performance on procedural knowledge and procedural flexibility items increased at midtest but decreased at posttest. Third, the pattern of results was consistent for students in the DragonBox and From Here to There! conditions, suggesting that both games may support students' conceptual understanding of algebra. The findings have implications for research and practice on supporting algebraic learning through game‐based technologies during and beyond educational disruptions.
CAD/CAM full‐mouth rehabilitation of an elderly patient: One‐piece digital complete denture meets multilayered zirconia with gradient technology
Authors: Edelhoff Daniel , Schubert Oliver , Stimmelmayr Michael , Schweiger Josef 
Published: March 2023

AbstractObjectiveThis article highlights a CAD/CAM complete‐mouth rehabilitation in an 82‐year‐old patient by means of a complete maxillary prosthesis and mandibular implant‐ and tooth‐supported fixed restorations made from multilayered zirconia.Clinical ConsiderationsComprehensive complete‐mouth rehabilitations in elderly patients with adaptation of the occlusal vertical dimension (OVD) often present particular challenges. This applies especially when exacting functional and esthetic requirements are to be met and the treatment should not cause the patient too much effort, still ensuring the highest level of quality and efficiency and a low intervention rate.ConclusionThe digital approach used for the present patient allowed for an efficient treatment procedure, facilitated virtual evaluations using a face‐scan, and enhanced the predictability of the prosthodontic outcome. The approach enabled some steps required in the conventional protocol to be omitted, resulting in a straightforward clinical treatment with minimal strain on the patient.Clinical SignificanceBecause of the comprehensive recording of extraoral and intraoral data, for example with a facial scanner, it was possible to transfer a digital replica of the patient to the dental laboratory technician. With this protocol, many steps can be performed in the absence of the real patient.
Missed opportunities for diagnosis of hepatitis B and C in individuals diagnosed with decompensated cirrhosis or hepatocellular carcinoma
Authors: Mnatzaganian George , MacLachlan Jennifer H , Allard Nicole , Brown Chelsea , Rowe Stacey , Cowie Benjamin C 
Published: March 2023

AbstractBackground and AimThis study aimed to assess utilization of health‐care services in people with decompensated cirrhosis (DC) or hepatocellular carcinoma (HCC) and a “late diagnosis” of hepatitis B or hepatitis C.MethodsHepatitis B and C cases during 1997–2016 in Victoria, Australia, were linked with hospitalizations, deaths, liver cancer diagnoses, and medical services. A late diagnosis was defined as hepatitis B or hepatitis C notification occurring after, at the same time, or within 2 years preceding an HCC/DC diagnosis. Services provided during the 10‐year period before HCC/DC diagnosis were assessed, including general practitioner (GP) or specialist visits, emergency department presentations, hospital admissions, and blood tests.ResultsOf the 25 766 notified cases of hepatitis B, 751 (2.9%) were diagnosed with HCC/DC, and hepatitis B was diagnosed late in 385 (51.3%). Of 44 317 cases of hepatitis C, 2576 (5.8%) were diagnosed with HCC/DC, and hepatitis C was diagnosed late in 857 (33.3%). Although late diagnosis dropped over time, missed opportunities for timely diagnosis were observed. Most people diagnosed late had visited a GP (97.4% for hepatitis B, 98.9% for hepatitis C) or had a blood test (90.9% for hepatitis B, 88.6% for hepatitis C) during the 10 years before HCC/DC diagnosis. The median number of GP visits was 24 and 32, and blood tests 7 and 8, for hepatitis B and C, respectively.ConclusionsLate diagnosis of viral hepatitis remains a concern, with the majority having frequent health‐care service provision in the preceding period, indicating missed opportunities for diagnosis.
Evaluation of peer‐mediated systems navigation for ageing families of individuals with developmental disabilities
Authors: Marsack‐Topolewski C. , Milberger S. , Janks E. , Anderson N. , Bray M. , Samuel P. S. 
Published: March 2023

AbstractBackgroundAs individuals with intellectual and developmental disabilities (I/DD) age, services often diminish, with many family caregivers experiencing challenges finding and navigating services. The purpose of this study was to examine the benefits of a state‐wide family support project for ageing caregivers (50+) of adults with I/DD in accessing and using services.MethodA one‐group pre‐test–post‐test design was used to determine if participation in the MI‐OCEAN intervention grounded in the Family Quality of Life (FQOL) theory reduced ageing caregivers' (n = 82) perceptions of barriers to accessing, using and needing formal services.ResultsAfter participating in the study, there was a reduction in reported barriers to accessing services. There was also greater use and reduced need for 10 of the 23 listed formal services.ConclusionsFindings indicate that a peer‐mediated intervention grounded in FQOL theory can be beneficial in empowering ageing caregivers by reducing perceived barriers to accessing services and increasing their use of advocacy and support services.
The afterlives of political violence in Argentina: The gendered body and everyday cruelty
Authors: Savloff Leyla 
Published: March 2023

AbstractWhile the last decade in Argentina saw an expansion of civil rights and an increased awareness of gendered violence, prison conditions for women deteriorated. A prominent example took place in Buenos Aires in May 2014 when thirty women in ‘Unidad 31’ were violently transferred to make space for men convicted of crimes against humanity during the last military dictatorship (1976‐1983). This event reveals how the repercussions of the last military dictatorship continue to unfold, displaying new iterations of military power. As former military men settled into a women's prison, the privileges of high‐ranking men expose how the afterlives of political violence reproduce gendered inequities in the prison system and, more broadly, in Argentine society. Drawing on three years of ethnographic fieldwork (2014‐2017), I consider how acts of resistance carried out by feminist collectives expose historical trauma and contemporary expressions of political violence.
Proposing novel dorsal Proatlas‐manifestations: Description and classification of three rare phenomena in humans
Authors: Wolf‐Vollenbröker Michael , Filler Timm Joachim , Prescher Andreas 
Published: March 2023

AbstractThe craniocervical junction (CCJ) of humans and other vertebrates is a developmental restless region. Due to complex phylogenetic and ontogenetic processes, many anatomical variations can be found in that transitional area. Therefore, newly described variants must be registered, named, and classified into existing concepts explaining their genesis. This study aimed to describe and classify anatomical peculiarities that have not or rarely been reported on before in the literature. This study is based on the observation, analysis, classification, and documentation of three rare phenomena of three different human skull bases and upper cervical vertebrae, which come from the body donor program of the RWTH Aachen. As a result, three osseous phenomena (accessory ossicles, spurs, and bridges) at the CCJ of three different body donors could have been documented, measured, and interpreted. Due to extensive collecting efforts, careful maceration, and accurate observation, it is still possible to add new phenomena to the long list of Proatlas‐manifestations. Further on, it could have been shown again that these manifestations can cause damage to the elements of the CCJ due to altered biomechanic conditions. Finally, we have succeeded in showing that phenomena can exist that can imitate the presence of a Proatlas‐manifestation. Here, a precise differentiation between Proatlas‐based supernumerary structures and the results of fibroostotic processes is necessary.
Satisfaction outcomes for patients and physicians following use of a new hyaluronic acid fillers
Authors: Torre Elena , Vetrano Stefano , Vertué Stefano , Zazzaron Michela , Russo Rosalba 
Published: March 2023

AbstractBackgroundThe aesthetic appearance of the skin, with the emergence of wrinkles, blemishes, and infraorbital hollowing, can be a cause of social distress and is a process exacerbated by aging. The presence of skin imperfections and aging is partly due to a loss of hyaluronic acid (HA), which normally contributes to a maintain a healthy and voluminous skin. Attempts to restore volume and revert the signs of aging have therefore focused on the use of dermatologic fillers based on HA.AimHere, we tested the safety and efficacy of MelHA®‐Monophasic Elastic Hyaluronic Acid (Concilium FEEL® filler products) containing HA at different concentrations and injected at different sites according to recommendations.MethodsFive different physicians assessed 42 patients across five different medical facilities in Italy, where they performed the treatment and assessed the patients after a follow‐up visit. Safety and efficacy of the treatment and change in quality of life after treatment were evaluated with two surveys, one directed to medical personnel, and one directed to patients.ResultsOur results show that, across all products and personalized treatments, patients', physicians' and “independent photography reviewer” satisfaction was very high and that the treatment show a favorable safety profile.ConclusionThese results are promising and suggest the use of Concilium Feel® filler products can contribute to an increased self‐esteem and quality of life in aging patients.