bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pharmacist Intervention to Address Drug Related Problems in Patients with Decompensated Liver Cirrhosis
Authors: Khazal Ameer A. , Jamal Mohammed Y. 
Published: April 2023

Background: Patients with decompensated cirrhosis are often given therapeutic and prophylactic drugs. Polypharmacy raises both the likelihood of prescription errors and the complications associated with drugs. Clinical pharmacists are excellent at recognizing, addressing, and preventing clinically significant drug-related problems.
Objectives: Identification types of pharmacist interventions to address drug-related problems in patients with decompensated cirrhosis and assess the acceptance/implementation of these recommendations. And identify patient factors associated with accepting pharmacist recommendations.
Subjects and Methods: Prospective, interventional, clinical study for 80 hospitalized decompensated cirrhosis patients was conducted at Baghdad Teaching Hospital and lasted for four months, from the first of December 2021 until the last of March 2022. The study involved two phases, the first one was observational to identify drug-related problems and classify them according to the Pharmaceutical Care Network Europe classification version 9.1, and the second phase was interventional to increase the awareness of patients and health care providers about those problems and to propose a proper solution for each one.
Results: The most frequent pharmacist intervention was proposed to the prescriber (54.7%), followed by speaking to the caregiver (37.7%). Acceptance and full implementation were highly observed in 71.1% of the intervention. There is a significant association between occurring ascites and bleeding in patients and accepting/implementing pharmacist recommendations
Conclusions: Patients with decompensated liver cirrhosis have a significant prevalence of drug-related problems. Clinical pharmacists are excellent at recognizing drug-related problems and reducing their incidence, and their interventions were well accepted.
The Surgical outcomes of fundus-first technique in lowering the rate of bile duct injuries and bleeding during open cholecystectomy that facing intraoperative difficulties: A single-center prospective study
Authors: Doush Wael Mohialddin , Abdelaziz Muataz S. , Musaad Abdlmagid M. 
Published: April 2023

Background: The problem of difficult gallbladder is not clearly defined and associated with real missing of therapeutic approaches that decreased morbidity. Moreover, the difficult gallbladder was reported as a contributing risk factor for biliary injury due to raised difficulty in surgical dissection within Calot’s triangle. The aim of this study is to determine the surgical outcomes of the open fundus-first cholecystectomy in lowering the rate of lethal intraoperative risks.
Subjects and Methods: Our prospective study conducted during the period of January 2019 to December 2022 at Ibn Sina specialized hospital, Khartoum, Sudan, for two hundred and fifty-three patients underwent elective open fundus-first cholecystectomy for intraoperative difficulties.
Results: the majority of cases had long-standing cholelithiasis with intraoperative difficulties revealed by pre-operative TUS and MRCP which required open fundus-first cholecystectomy in 173 (68.4%) of patients, (P-value <0.05). The operative surgical time was 120 minutes in 103 patients (40.7%), (P-value <0.05). During open cholecystectomy, variable intraoperative difficulties were found in all patients, (P-value <0.05) and were divided into: (A) Contracted intra-hepatic gallbladder seen in 157 (62.1%) of cases; (B) Distorted anatomy within Calot's triangle seen in 135 (53.4%) of patients; and (C) Intraoperative bleeding from the liver bed was observed as bloody oozing form in 150 (59.3%) of cases. Our patients had minimal postoperative complications like mild wound infection in 8 (3.2%) of cases and mortality rate was zero.
Conclusions: There is a need for appropriate therapeutic and preventive strategies in healthcare systems for safe dealing with difﬁcult cholecystectomy. Unclear anatomy due to severe inflammatory dense adhesions at Calot’s triangle and CBD stones needing difficult surgeries are the most important limiting factors for fundus-first laparoscopic cholecystectomy. Hence, we humbly recommend an open approach of fundus-first cholecystectomy as safe surgical option to reduce the incidence of bile duct injuries and intra-operative bleeding.
Effect of Investments on Cash flow of Manufacturing Firms Listed at the Nairobi Securities Exchange
Authors: Musembi Damaris Mutindi , Sporta Fred 
Published: April 2023

The researcher in this study sought to establish the factors that affect cash flow in manufacturing firms in Kenya. The study was guided by the following specific objectives,to establish how investments affect cash flow in manufacturing firms listed in the Nairobi stock exchange, to find out how inventory controls affect cash flow in manufacturing firms listed in the Nairobi stock exchange, to determine how profitability affect cash flow in manufacturing firms listed in the Nairobi stock exchange. The researcher used descriptive research design to describe the factors affecting cash flow in manufacturing firms listed in the Nairobi stock exchange. A firm should be able to generate enough cash flows from its operations. If a firm is not able to cover its current liabilities with cash generated from operations, it will have cash challenges in financing its operations. A cash flow ratio of oneshow that the firm has healthy cash flows and a ratio of less than one shows that the firm does not have enough cash flows to finance its operations. The study covered a period of five years from 2012 to 2017.The methodology for the study was descriptive research design. The study employed population census as the listed firms were very few for the researcher to employ sampling. The listed firms were nine. Analyzed data was presented using figures and tables. The study findings revealed that there is a positive relationship between cash flows and investments as measured by net capital expenditure, profitability as measured by return on assets. There is a negative relationship between cash flows and inventory control as measured by inventory turnover. The study also established that there is a positive relationship between cash flows and profitability of a firm as measured by return on Assets (ROA).cash flows in all the firms have the same trend expect for Eveready East African ltd. The study concluded that manufacturing firms should exercise inventory control, invest wisely and also manage profitability of assets to ensure that the firm has enough cash flows to fund its operations
Central Bank Policy and Commercial Banks Distress Level in Nigeria
Authors: Wachukwu Princewill Ihenacho , Iwedi Marshal , Barisua Sirah Patience 
Published: April 2023

This study investigated the impact of central bank policy on commercial bank distress Level in Nigeria. Financial time series data were obtained from the central bank of Nigeria statistical bulletin. The data collected were tested using the vector auto regression analysis. The study established that 99.3 percent variation in commercial bank distress level in Nigeria is accounted for by the combined efforts of the explanatory variables of the study. The study concludes that Central Bank of Nigeria must continuously monitor the level of liquidity in order to mitigate any adverse impact on the stability of the financial system.
Agglomeration of population and employment in the urbanization - industrialization interaction: The case of Izmir
Authors: Yetiskul Emine , Kul Fahrettin 
Published: April 2023

As production and economic activities shaped the growth of cities during the pre-industrial era, they are still the most important factors explaining modern urbanization. Economic restructuring is being reshaped with agglomeration economies, bringing spatial restructuring with it. Regional economic growth, emergence of new centers and production foci are formed in the equilibria of positive and negative externalities of agglomeration. Positive externalities do not arise solely from internal economies of scale related to factors of production such as easy accessibility in the region. It also results from external economies of scale, including economies of localization and urbanization. On the other hand, as cities grow the attractiveness of large agglomeration and advantages of economies of scale decrease. Negative externalities in the larger agglomerations may eventually lead to decreasing returns to scale in cities. Economic view of regional science and geography considers cities maintaining equilibrium between two competing forces, i.e., centripetal forces (agglomeration) and centrifugal forces (dispersion). This study examines recent agglomeration and dispersion processes in the settlement pattern from the relationship between urbanization and economic growth. To do so, we take Izmir as a case and use general explanatory variables such as population and employment. Specifically, we investigate spatial agglomeration in the Izmir city region and metropolitan area by using population and employment data of 2009 and 2019. Based on empirical results, we discuss new sub-regions, urban centers, and clustering that emerged due to economies of scale as well as positive and negative externalities of agglomeration.
Alternative Dispute Resolution (ADR): A Suitable Broad Based Dispute Resolution Model in Nigeria; Challenges and Prospects.
Authors: Ojo Samuel Olugbenga 
Published: April 2023

Purpose: Due to the flaws in the traditional judicial system, the use of Alternative Dispute Resolution (ADR) methods is gaining popularity among scholars and lawyers around the world. Most scholarly articles have examined the inherent advantages of Alternative Dispute Resolution (ADR) techniques over the traditional judicial processes for resolving different types of conflict. Despite the increasing frequency and classification of conflicts in Nigeria, little research has been conducted on the reasons for, and barriers to, disputants' use of alternative dispute resolution (ADR) systems as viable options. Given the complexity of the nature and structure of disputes in Nigeria, this research delves into the factors that push and pull litigants into the use of Alternative Dispute Resolution (ADR).
Methodology: This study utilized an explanatory research approach to investigate the many distinctive kinds of conflicts and match them with the most relevant ADR procedures. In particular, property disputes, family conflicts, and business disagreements were investigated.
Findings: According to the findings, Alternative Dispute resolution (ADR) may lead to a considerable reduction in the amount of time and expense of the dispensation of justice that addresses unfairness in the system of criminal justice administration, ultimately resulting in positive social change.
Contributions to Theory, Policy and Practice: The study concludes that Alternative Dispute Resolution (ADR) processes have significant potentials for handling the growing number of disputes. However, it is necessary to address their shortcomings as well as facilitate collaboration between the practitioners and the regular courts. It would improve social stability and guarantee satisfaction for the perpetrator, the victim, the community, and society as a whole if this were done. The study recommended, among other things, that the general public and litigants be educated on the inherent advantages of Alternative Dispute Resolution (ADR) in the resolution of conflicts.
Formulation and Phytochemical Profile of a Product Prototype Infused with Cannabis sativa Leaves
Authors: Tongkasee Pongsathorn , Srithat Dutsdee , Sriyasak Patcharawalai , Jitcharerntham Anunkaorn , Piwgern Teera , Khoontawad Jarinya , Insuwan Wilaiporn 
Published: April 2023

This study investigated the formulation of a product prototype RMUTI-SKC by using the legal part of cannabis plants (leaves). Five product prototypes were composed of cannabis (leaves), stevia and mint. The herbs were added to improve the taste, smell and physical appearance properties of the product prototype which was yellowish-green. The analysis of the chemical properties found no heavy metals (Cd, As, and Pb) were observed (based on THAI community product standard, and demonstrated a moderate antioxidant activity, total phenolic content and total flavonoid content. The GC-MS profile of crude extracts analysis revealed the phytochemicals based on pharmacological action of essential oil, flavoring substance, anti-inflammatory, antioxidant, anti-bacterial, antidiabetic, antifungal and anti-cancer, respectively. The experimental results showed the pharmacological properties of the product prototype which can be a guideline for applying cannabis plants to other products. Further study on pathogen testing and product aging should be carried out to satisfy the quality of production.
HIGHLIGHTS

The formulation of a product prototype RMUTI-SKC by using the legal part of cannabis plants (leaves). The analysis of the chemical properties found no heavy metals (Cd, As and Pb) were observed (based on THAI community product standard, and demonstrated a moderate antioxidant activity, total phenolic content and total flavonoid content.

GRAPHICAL ABSTRACT
FORMAÇÃO DE PROFESSORES INDÍGENAS NO ESTADO DO TOCANTINS
Authors: Lima Jandira Rodrigues Aquino , Freire José Carlos da Silveira 
Published: April 2023

Este artigo aborda a formação de professores indígenas desde 1991, quando o Ministério da Educação – MEC, conduziu os processos de educação, junto aos povos indígenas do Estado do Tocantins. Para tanto, as pesquisas bibliográficas foram realizadas em livros, dissertações, artigos e documentos em várias esferas governamentais, sobre experiências e políticas públicas de formação dos indígenas. Nesse contexto, é apresentada a política de formação para professores indígenas no Estado do Tocantins, o curso de formação de professores: Projeto de Educação Indígena para o Estado do Tocantins e a Proposta de Formação de Professores Indígenas do Estado do Tocantins. Escrever este Artigo configura a concretização de um desejo que há tempos nutria em meu coração e o interesse por essa temática, tem sido atribuído à necessidade da oferta de uma educação de qualidade e na busca de um modelo de formação indígena, capaz de articular as demandas de qualificação docente e valorização da cultura indígena no currículo escolar.
É POSSÍVEL PARA REDIMIR-SE DA INSUFICIÊNCIA NA LITERATURA GUINEENSE NA SALA DE AULA ATRAVÉS DA POLÍTICA EDUCACIONAL: DESCOBRIR A SUA IMPORTÂNCIA DE APRENDÊ-LA PELA REVALORIZAÇÃO CULTURAL
Authors: Sané Manga , Scherma Camila Caracelli 
Published: April 2023

A Guiné-Bissau é um país colonizado pelos portugueses e sofreu-se profundamente a opressão dos mesmos sobre o povo guineense, por outro lado, uma opressão que se vincula à política e a religiosidade dos mesmos logo a sua chegada ao território em 1446 até 24 de setembro de 1973, em que época, o PAIGC (Partido Africano Para a Independência da Guiné e Cabo Verde) proclamou a sua autonomia unilateral, a pós uma década de luta armada contra os colonizadores que tinham se posicionados em aniquilar supostamente todos os valores culturais guineense, nesta circunstância, essa política implantou-se entre guineenses, a cultura europeia, de uma forma radicalizada e ignora a cultura guineense. Neste âmbito, o trabalho mostra-se que é possível para redimir-se da insuficiência na literatura guineense na sala de aula através da política educacional: descobrir a sua importância de aprendê-la pela revalorização cultural. Neste contexto, com base no tema acima apresentado, assim, pretende-se, basicamente, a analisar às obras dos autores nos quais, hipoteticamente, podem sustentar na pesquisa, por exemplo, Bâ (2003); Ribeiro e Semedo (2011); Da Cruz e Dos Santos (2019). Nesta conjuntura, metodologicamente, realiza-se a pesquisa bibliográfica, a razão pela qual, opta-se por pesquisar artigos científicos, livros, romances etc. com intuito de compilar o objeto pesquisado. Neste cenário, pode-se perceber que a Guiné-Bissau, presumivelmente, os materiais didáticos são modelos da Europa e provavelmente que não condescende em nenhum momento da autenticidade da população local. Com isso, ao longo da pesquisa feita, pois, vale a pena reconhecer que a Guiné-Bissau como é um país constituído com multiétnico, plurilinguismo, étnico-cultural e multirracial, neste caso, é possível revalorizar todas as culturas para compilar nos materiais didáticos e usá-los como armas de persuasão com a finalidade de descontruir a política dos colonizadores herdada das elites guineenses.
O IMPACTO DO TRATAMENTO FARMACOLÓGICO NA VIDA DOS PACIENTES COM FIBROSE CÍSTICA
Authors: Almeida Ricardo Sousa de , Silva Isabella Andrade Louzada Barreto da , Bugalho Bisneto Manoel Rodrigues , Pires Ana Carla Lírio , Oliveira Cristiane Metzker Santana de 
Published: April 2023

Levando em conta que os indivíduos com fibrose cística são submetidos a tratamento medicamentoso complexo, pesquisa-se sobre o impacto do tratamento farmacológico na vida dos pacientes com fibrose cística., com o intuito de promover o conhecimento a respeito das implicações do tratamento medicamentoso da mucoviscidose . Para tanto, é necessário conceituar a fibrose cística e as suas repercuções clínicas, relacionar o tratamento farmacológico da fibrose cística com a qualidade de vida do paciente e evidenciar a importância do farmacêutico clínico no suporte ao paciente fibrocístico. Realiza-se, então, uma pesquisa de revisão de literatura. Diante disso, verifica-se que apesar dos avanços notórios no tratamento que contribuíram para maior sobrevida, o tratamento, em certo aspecto, tem apresentado alguns ônus para os pacientes por estar se tornando ainda mais complexo e oneroso, juntamente com os avanços. Nesse contexto, o fator qualidade de vida passa a ganhar mais evidência tanto em meio a pacientes, quanto entre os profissionais de saúde. Nesse contexto a necessidade aperfeiçoar o tratamento diminuindo sua carga e impactos negativos, ganha espaço. Dessa forma é reforçada a importância de incluir o farmacêutico, de forma ativa, na equipe de tratamento desses pacientes, pelas diversas capacidades desse profissional à respeito da gestão do tratamento, fator crucial para sobrevida e qualidade de vida do paciente com fibrose cística.
HISTÓRIA, MEMÓRIA E DOCUMENTO: A IMPORTÂNCIA DA HISTORIOGRAFIA DOCUMENTAL LOCAL PARA A DIFUSÃO DO SABER
Authors: Batista Grescyelly Neves 
Published: April 2023

Contar a história de um lugar requer uma escuta ativa de relato oral e análise de informações e registros, para que o compilado de elementos deem origem a História de um lugar de um povo, que formam um conjunto: o patrimônio documental. Este estudo tem por finalidade expor um relato de experiência da produção de um livro que conta a história de uma cidade no coração da Amazônia e destaca ainda a importância da preservação da memória individual e coletiva em relação ao documento, história e memória, com vistas ao acesso à informação para as futuras gerações. Trata-se de uma pesquisa bibliográfica. Assim, delimitou-se o uso de materiais publicados em livros, documentários, buscas a registros oficiais em instituições públicas, fotografias, relatos orais e internet. O intuito da criação de patrimônio documental é oportunizar ao povo o acesso à memória, para formar sua identidade, favorecendo o direito da sociedade ao acesso à sua própria história.
O SILÊNCIO ÀS VOZES FEMININAS: UMA ANÁLISE COMPARATIVA ENTRE A MULHER BRASILEIRA CONTEMPORÂNEA E O LIVRO VOX
Authors: Leite Maria Ingridi da Silva , Oliveira Edjôfre Coelho de 
Published: April 2023

O presente estudo tem por finalidade analisar o silêncio imposto à figura feminina na sociedade por meio da literatura comparada com o livro VOX, de Christina Dalcher. Este estudo foi aprofundado por meio de pesquisa bibliográfica narrativa com abordagem dedutiva e com a finalidade de analisar o silenciamento à voz feminina nas leis brasileiras vivenciado na sociedade contemporânea. Com relevância social, uma vez que discutir a participação da mulher em todos os aspectos da sociedade é condição necessária à equiparação entre direitos e participações sociais. O tema em questão interliga a realidade da mulher na sociedade brasileira à problemática da violência feminina de forma associada à área do Direito e da Literatura com base no livro VOX, demonstrando também que essa violência é algo característico de uma sociedade baseada em conceitos machistas, uma vez que foram analisados dados, realidade, obra literária – a qual é um reflexo do momento histórico social dos indivíduos, pois apresenta uma mímise daquele contexto em que ela foi escrita a fim de mostrar que, para haver uma mudança na problemática abordada, deve-se haver mudança de todo um pensamento social arcaico vinculado à figura feminina e aos papéis dessa em seu ambiente de convívio.
CRIME DE RESPONSABILIDADE: IMPEACHMENT – CASO DA DILMA ROUSSEFF
Authors: Silva Nicole Coely Oliveira da , Fernandes Adriano Ferreira 
Published: April 2023

O artigo tem como objetivo, o estudo do processo do impeachment analisando a natureza jurídica do processo. Previsto na Constituição de 1988, no art. 85 incisos I a VII e na Lei 1.079/50 de 1950, que é proveniente o crime de responsabilidade. Visa-se também assinalar as diferenças entre infração penal (crimes comuns) e a infração de responsabilidade, demonstrando também as etapas processuais bem como as consequências do crime de responsabilidade: Impeachment. Além disso, iremos abordar um de inúmeros casos de impeachment, o caso de Dilma Rousseff que ocorreu no decorrer de 2016, seu procedimento e a forma como ocorreu. O Brasil foi um dos primeiros a concretizar o processo completo de impeachment, como pode ser visto no caso do Collor.
BENEFÍCIOS DO HIGH INTENSITY INTERVAL TRAINING - HIIT NA COMPOSIÇÃO CORPORAL FEMININA
Authors: Fernandes Thayna Evangelista , Oliveira Thiago José de , Souza Anderson da Silva , Motta Roberto Cesar Pereira da , Oliveira Junior Wallace José Chicarino 
Published: April 2023

A nível mundial, a busca constante pelo corpo descrito como “ideal” - disseminado às grandes massas pelos meios de comunicação - tem tomado proporções inimagináveis. Assim, a busca frenética por exercícios que forneçam bons resultados, em curto espaço de tempo, estão no topo da lista relacionada a busca do corpo ideal, principalmente no público feminino. Sob essa perspectiva muitos exercícios se ajustam a rotina do dia a dia e a falta de tempo, entre eles o HIIT (High Intensity Interval Training), que em português significa Treino Intervalado de Alta Intensidade. Com base no exposto, o objetivo deste artigo é propor uma revisão de literatura sobre a influência HIIT na composição corporal feminina. Com base nos diversos autores e estudos analisados, foi possível concluir que independente da condição física, ou da faixa etária, grau de obesidade ou de sedentarismo, com síndromes e doenças crônicas não-transmissíveis, ou com boa saúde e aptidão física, o HIIT se demonstra uma ótima ferramenta para a mudança significativa na composição corporal feminina, bem como mudanças estéticas e funcionais do corpo de maneira geral.