bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transient side shift of cluster headache attacks after unilateral greater occipital nerve injection
Authors: Brandt Roemer B. , Naber Willemijn C. , Ouwehand Rosa‐Lin H. , Haan Joost , Ferrari Michel D. , Fronczek Rolf 
Published: June 2023

AbstractAttacks of cluster headache (CH) are usually side‐locked in most, but not all, patients. In a few patients, the side may alternate between or, rarely, within cluster episodes. We observed seven cases in whom the side of CH attacks temporarily shifted immediately or shortly after unilateral injection of the greater occipital nerve (GON) with corticosteroids. In five patients with previously side‐locked CH attacks and in two patients with previously side‐alternating CH attacks, a side shift for several weeks occurred immediately (N = 6) or shortly (N = 1) after GON injection. We concluded that unilateral GON injections might cause a transient side shift of CH attacks through inhibition of the ipsilateral hypothalamic attack generator causing relative overactivity of the contralateral side. The potential benefit of bilateral GON injection in patients who experienced a side shift after unilateral injection should be formally investigated.
‘Creating a culturally competent pharmacy profession’: A qualitative exploration of pharmacy staff perspectives of cultural competence and its training in community pharmacy settings
Authors: McCann Jessica , Lau Wing Man , Husband Andy , Todd Adam , Sile Laura , Doll Amandeep Kaur , Varia Sneha , Robinson‐Barella Anna 
Published: June 2023

AbstractIntroductionCultural competence is an important attribute underpinning interactions between healthcare professionals, such as pharmacists, and patients from ethnic minority communities. Health‐ and medicines‐related inequalities affecting people from underrepresented ethnic groups, such as poorer access to healthcare services and poorer overall treatment outcomes in comparison to their White counterparts, have been widely discussed in the literature. Community pharmacies are the first port of call for healthcare services accessed by diverse patient populations; yet, limited research exists which explores the perceptions of culturally competent care within the profession, or the delivery of cultural competence training to community pharmacy staff. This research seeks to gather perspectives of community pharmacy teams relating to cultural competence and identify possible approaches for the adoption of cultural competence training.MethodsSemistructured interviews were conducted in‐person, over the telephone or via video call, between October and December 2022. Perspectives on cultural competence and training were discussed. Interviews were audio‐recorded and transcribed verbatim. The reflexive thematic analysis enabled the development of themes. QSR NVivo (Version 12) facilitated data management. Ethical approval was obtained from the Newcastle University Ethics Committee (reference: 25680/2022).ResultsFourteen participants working in community pharmacies were interviewed, including eight qualified pharmacists, one foundation trainee pharmacist, three pharmacy technicians/dispensers and two counter assistants. Three themes were developed from the data which centred on (1) defining and appreciating cultural competency within pharmacy services; (2) identifying pharmacies as ‘cultural hubs’ for members of the diverse, local community and (3) delivering cultural competence training for the pharmacy profession.ConclusionThe results of this study offer new insights and suggestions on the delivery of cultural competence training to community pharmacy staff, students and trainees entering the profession. Collaborative co‐design approaches between patients and pharmacy staff could enable improved design, implementation and delivery of culturally competent pharmacy services.Patient or Public ContributionThe Patient and Public Involvement and Engagement group at Newcastle University had input in the study design and conceptualisation. Two patient champions inputted to ensure that the study was conducted, and the findings were reported, with cultural sensitivity.
A Community of Practice to increase education and collaboration in dementia and ageing research and care: The Liverpool Dementia & Ageing Research Forum
Authors: Giebel Clarissa , Tetlow Hilary , Faulkner Thomas , Eley Ruth 
Published: June 2023

AbstractBackgroundToo often, dementia research is conducted in research silos without thorough integration and the involvement of people with lived experiences, care professionals and the Third Sector. Research can also get lost in academic publications, without reaching those benefiting most from the evidence. The aim of this methods and evaluation paper was to outline the aims, components and evaluation of the public‐facing and ‐engaging Liverpool Dementia & Ageing Research Forum, to provide a blueprint for setting up similar communities of practice.MethodsThe Forum was set up in 2019 with the aim to (a) connect different stakeholders in dementia and ageing and co‐produce research and to (b) inform and educate. This paper provides an account of the Forum model and evaluates the following key elements: (1) engagement; (2) experiences of the Forum and its impact (via an online evaluation survey and three reflections). All Forum members and attendees were asked to complete a brief evaluation survey about their experiences from October to November 2022. Three regular Forum attendees provided a case study about their involvement and its impact.FindingsThe Forum has reached out to diverse stakeholders and the general public, generating growing interest and engagement since its initiation. Forty‐four members and attendees completed the survey. Most attendees completing the evaluation survey have so far engaged in between 5 and 20 activities (47.8%), and 91% felt the aims of the Forum have been met. Engaging in the Forum has produced various benefits for attendees, including increased research capacity and knowledge, as well as improved connectivity with other stakeholders. Eleven percent of respondents, 39% of lived experts, stated they experienced improved access to postdiagnostic care.ConclusionsThis is the first reported multistakeholder Community of Practice (CoP) on dementia and ageing. We make key recommendations for setting up and running similar dementia CoP, as they provide a noninterventional format for raising awareness, capacity and access to dementia care.Patient and Public InvolvementThis paper reports on the involvement and engagement of people with dementia, unpaid carers, health and social care providers and Third Sector organisations in a CoP.
Using mid‐infrared spectroscopy combined with chemometrics to determine digested starch and maltose concentration during in‐vitro digestion of starches
Authors: Visnupriyan Ramanah , Flanagan Bernadine , Harper Karen , Cozzolino Daniel 
Published: June 2023

SummaryStarch digestion is typically evaluated using in‐vitro techniques. During and after the in‐vitro digestion, samples are collected (gastric and intestinal phases) at allotted time intervals where starch digestion is quantified through the analysis of sugars using routine chemical and enzymatic analysis. This paper reports the use of mid‐infrared (MIR) spectroscopy as rapid method to measure the concentration of maltose and % digested starch during the digestion of rice and potato starch, maize starch namely Gelose 50 (50% amylose), Gelose 80 (80% amylose) and pregelatinized corn starch collected at different time points (5, 10, 15, 20, 25, 30, 40, 50, 60, 75, 90, 105 and 120 min) from two in‐vitro digestion experiments. Two types of samples, turbid and supernatant were also evaluated. The coefficient of determination (R2) and the standard error in cross‐validation (SECV) ranged between 0.74 to 0.93 and 163 to 360 μg mL−1 for the prediction of the concentration of maltose. The use of turbid samples showed a better predictive ability when compared with the regression models developed using the supernatant samples. This method showed potential to significantly decrease the time and effort associated to determining maltose concentration and % digested starch during in‐vitro digestion.
The effects of gamma irradiation treatment on starch structure and properties: a review
Authors: Zhiguang Chen , Rui Zhou , Qi Yang , Haixia Zhong 
Published: June 2023

SummaryGamma irradiation is a new starch processing and modification method. In this paper, the effects of gamma irradiation on starch structure and properties were summarised and discussed. In terms of starch structure, gamma irradiation destroys glycosidic bonds and significantly reduces the average molecular weight of starch, which may be the fundamental reason for the change in starch properties after irradiation. In addition, irradiation has no effects on crystal type but decreases the crystallinity of starch. Meanwhile, gamma irradiation can increase the specific surface area of starch granules but have no significant effects on the granular morphologies, indicating the damage to starch granules caused by irradiation proceeds from inside the granules. In terms of starch properties, gamma irradiation treatment decreases the viscosity, setback, breakdown, To, Tp, Tc, the enthalpy of crystalline melting, storage modulus, loss modulus, consistency coefficient and swelling ability of starches. In addition, gamma irradiation increases the b value, water absorption capacity, oil absorption capacity and solubility of starches. However, the results of the effects of irradiation on starch digestive, retrogradation and texture properties are not consistent in different studies. It may provide a reference for the application of irradiation in starch processing and modification.
The role of sense of coherence in workplace violence directed at nurses in the shadow of COVID‐19: A cross‐sectional study
Authors: Amit‐Aharon Anat , Warshawski Sigalit , Itzhaki Michal 
Published: June 2023

AbstractAimsTo explore (a) the associations between sense of coherence (SOC), previous exposure to COVID‐19, and the intention to act violently towards nurses, and (b) the role of SOC and sociodemographic variables as risk or protective factors involved in the intention to act violently.DesignA cross‐sectional study with a convenience sample.MethodsA structured self‐report questionnaire was distributed from February to March 2022. The questionnaire included socioeconomic variables, previous exposure to COVID‐19, and a validated questionnaire on SOC. Three vignettes (online shaming, verbal and physical violence) describing nurse–patient communication conflicts were presented to participants. A multinomial logistic regression was conducted to explore the associations with acting violently by comparing three options of no/sometimes/high intention to act violently. The study adhered to STROBE guidelines.ResultsQuestionnaires were completed by 808 adults. SOC and religiosity were revealed as protective factors in the three vignettes. Verbal violent behaviour was found to be a risk factor for online and physical violent behaviour intention. Previous exposure to COVID‐19, non‐academic education, and ethnicity were found to be risk factors for the intention to behave violently toward nurses.ConclusionThe findings suggest that training nurses in practical SOC dimensions (enhancing comprehensible, manageable and meaningful treatment processes) may reduce patients' lack of understanding and frustration and, in turn, reduce the tendency to behave violently.ImpactThis study focused on SOC as a variable that may affect the intention to act violently towards nurses. The results reveal that SOC may be a protective factor, where people with higher SOC will have less intention to behave violently towards nurses. The results can provide an insight for nurses, nurse leaders and policymakers, towards supplying coherent and cultural competency treatment processes for patients and assisting nurses in dealing with stressful situations during normal routines and pandemics.Patient or Public ContributionThe questionnaire was distributed among the general public by master's degree nursing students. The students distributed the questionnaires among their friends and acquaintances using a snowball‐sampling approach.
Nakedly Normative: A Feminist (Re‐)Imagination of Planetary Politics
Authors: David Maxine , Guerrina Roberta , Wright Katharine A. M. 
Published: June 2023

AbstractThis article makes the case for a feminist (re‐)imagination of planetary politics in the context of the normative power approach and Manners' opening article in this special section. Arguing for an urgent turn to a politics that embraces the whole of the planet, we ask: How can we build processes and political structures that equip us with what is needed to manage those tests now faced by the planet? We apply a critical feminist lens to argue that the potential of a normative power approach in realising a planetary politics, so challenging anthropocentrism, can only be fulfilled if political and societal actors embrace four ‘Es’: ethic of care, empathy, emancipation and equity. The cosmopolity envisioned is premised on our ability to ‘see’, ‘hear’, question – perhaps even break with – the disciplining and bounding effects of the disciplines that feed into European studies.
Introgression between highly divergent fungal sister species
Authors: Kinneberg Vilde Bruhn , Lü Dabao Sun , Peris David , Ravinet Mark , Skrede Inger 
Published: June 2023

Abstract
To understand how species evolve and adapt to changing environments, it is important to study gene flow and introgression due to their influence on speciation and radiation events. Here, we apply a novel experimental system for investigating these mechanisms using natural populations. The system is based on two fungal sister species with morphological and ecological similarities occurring in overlapping habitats. We examined introgression between these species by conducting whole genome sequencing of individuals from populations in North America and Europe. We assessed genome-wide nucleotide divergence and performed crossing experiments to study reproductive barriers. We further used ABBA–BABA statistics together with a network analysis to investigate introgression, and conducted demographic modelling to gain insight into divergence times and introgression events. The results revealed that the species are highly divergent and incompatible in vitro. Despite this, small regions of introgression were scattered throughout the genomes and one introgression event likely involves a ghost population (extant or extinct). This study demonstrates that introgression can be found among divergent species and that population histories can be studied without collections of all the populations involved. Moreover, the experimental system is shown to be a useful tool for research on reproductive isolation in natural populations.
Abstract
We studied population histories with demographic modelling and found introgression between highly divergent fungal sister species, involving a ghost population.
The need to consider ‘temporality’ in person‐centred care of people with motor neurone disease
Authors: Harris Denise A. , Jack Kirsten , Wibberley Christopher 
Published: June 2023

AbstractAims and ObjectivesThe overall aim of this paper is to provide practical insight into the way that professionals caring for a person with motor neurone disease (MND) can recognise, respect and respond to that person's temporality; that is, the person that they have been, that they are now and that they will be in the future.BackgroundMND is an umbrella term for a group of four rare, devastating neurodegenerative terminal diseases of middle/later life. Previously, we have acknowledged the importance of different time periods in the trajectory of MND as an illness, for example, during the diagnosis stage through to end of life and decision‐making at that time. Living with MND can cause anxiety at all stages of the disease trajectory especially as it can be difficult for people living with MND to communicate their desires and concerns to professionals and carers. It is important that professionals continue to provide holistic care throughout the illness trajectory and the aim of this paper is to explore past research about caring for someone with MND in relation to the concept of person‐centred care.MethodThe paper is based on the concatenated exploration of the findings of a hermeneutic phenomenological project. Thus, this discursive paper links elements/studies which have been published previously to develop a model of person‐centred care for people with MND which recognises and respects their temporality.ConclusionsWe suggest MND has a significant impact on a person's lifeworld. The proposed person‐centred care model focuses on understanding (interpreting) a person in a wider temporal frame and beyond the context of their illness. The expected collaborative outcomes are that: a person is acknowledged as more than a ‘patient with MND’ and that a professional is providing person‐centred care based on individuality of the person, through a temporal lens. This requires a collaborative approach between the person, others and professionals. Such person‐centred care, focused on individuality, may prevent a person experiencing life in crisis and suffering towards the end of life.
Perceived Stress and Depressive Symptoms Are Associated With Emotional Eating but Not Nutritional Intake During Pregnancy: A Prospective Cohort Study
Authors: Carandang Rogie Royce , Epel Elissa , Radin Rachel , Lewis Jessica B. , Ickovics Jeannette R. , Cunningham Shayna D. 
Published: June 2023

IntroductionPregnancy is a major life event during which women may experience increased psychological distress and changes in eating behaviors. However, few studies have investigated the influence of psychological distress on pregnant women's eating behaviors. The primary objective of this prospective study was to examine the associations of changes in perceived stress and depressive symptoms with emotional eating and nutritional intake during pregnancy. In addition, we examined the direct and moderating effects of perceived social support.MethodsParticipants were racially diverse pregnant women (14‐42 years) from 4 clinical sites in Detroit, MI, and Nashville, TN (N = 678). We used multiple linear and logistic regression models to determine if changes in stress and depressive symptoms across pregnancy were associated with changes in emotional eating and nutritional intake. We examined residualized change in stress and depressive symptoms from second to third trimester of pregnancy; positive residualized change scores indicated increased stress and depressive symptoms.ResultsParticipants showed significant improvement in emotional eating and nutritional intake from second to third trimester of pregnancy (P < .001 for both). At second trimester, higher depressive symptoms were associated with a greater likelihood of emotional eating (P < .001) and worse nutritional intake (P = .044) at third trimester. Increased stress and depressive symptoms during pregnancy were both associated with increased risk, whereas increased perceived social support reduced risk of emotional eating at third trimester (stress: adjusted odds ratio [AOR], 1.17; 95% CI, 1.08‐1.26; depressive symptoms: AOR, 1.05; 95% CI, 1.01‐1.08; social support: AOR, 0.93; 95% CI, 0.88‐0.99). None were associated with changes in nutritional intake. Perceived social support did not show any moderating effects.DiscussionIncreased psychological distress during pregnancy may increase emotional eating. Efforts to promote healthy eating behaviors among pregnant women should consider and address mental health.
Gene expression profiling in whole blood stimulated ex vivo with lipopolysaccharide as a tool to predict post‐stroke depressive symptoms: Proof‐of‐concept study
Authors: Piechota Marcin , Hoinkis Dzesika , Korostynski Michal , Golda Slawomir , Pera Joanna , Dziedzic Tomasz 
Published: June 2023

AbstractPrediction of post‐stroke depressive symptoms (DSs) is challenging in patients without a history of depression. Gene expression profiling in blood cells may facilitate the search for biomarkers. The use of an ex vivo stimulus to the blood helps to reveal differences in gene profiles by reducing variation in gene expression. We conducted a proof‐of‐concept study to determine the usefulness of gene expression profiling in lipopolysaccharide (LPS)‐stimulated blood for predicting post‐stroke DS. Out of 262 enrolled patients with ischemic stroke, we included 96 patients without a pre‐stroke history of depression and not taking any anti‐depressive medication before or during the first 3 months after stroke. We assessed DS at 3 months after stroke using the Patient Health Questionnaire‐9. We used RNA sequencing to determine the gene expression profile in LPS‐stimulated blood samples taken on day 3 after stroke. We constructed a risk prediction model using a principal component analysis combined with logistic regression. We diagnosed post‐stroke DS in 17.7% of patients. Expression of 510 genes differed between patients with and without DS. A model containing 6 genes (PKM, PRRC2C, NUP188, CHMP3, H2AC8, NOP10) displayed very good discriminatory properties (area under the curve: 0.95) with the sensitivity of 0.94 and specificity of 0.85. Our results suggest the potential utility of gene expression profiling in whole blood stimulated with LPS for predicting post‐stroke DS. This method could be useful for searching biomarkers of post‐stroke depression.image
3D atlas of tinamou (Neornithes: Tinamidae) pectoral morphology: Implications for reconstructing the ancestral neornithine flight apparatus
Authors: Widrig Klara E. , Bhullar Bhart‐Anjan S. , Field Daniel J. 
Published: June 2023

AbstractPalaeognathae, the extant avian clade comprising the flightless ratites and flight‐capable tinamous (Tinamidae), is the sister group to all other living birds, and recent phylogenetic studies illustrate that tinamous are phylogenetically nested within a paraphyletic assemblage of ratites. As the only extant palaeognaths that have retained the ability to fly, tinamous may provide key information on the nature of the flight apparatus of ancestral crown palaeognaths—and, in turn, crown birds—as well as insight into convergent modifications to the wing apparatus among extant ratite lineages. To reveal new information about the musculoskeletal anatomy of tinamous and facilitate development of computational biomechanical models of tinamou wing function, we generated a three‐dimensional musculoskeletal model of the flight apparatus of the extant Andean tinamou (Nothoprocta pentlandii) using diffusible iodine‐based contrast‐enhanced computed tomography (diceCT). Origins and insertions of the pectoral flight musculature of N. pentlandii are generally consistent with those of other extant volant birds specialized for burst flight, and the entire suite of presumed ancestral neornithine flight muscles are present in N. pentlandii with the exception of the biceps slip. The pectoralis and supracoracoideus muscles are robust, similar to the condition in other extant burst‐flying birds such as many extant Galliformes. Contrary to the condition in most extant Neognathae (the sister clade to Palaeognathae), the insertion of the pronator superficialis has a greater distal extent than the pronator profundus, although most other anatomical observations are broadly consistent with the conditions observed in extant neognaths. This work will help form a basis for future comparative studies of the avian musculoskeletal system, with implications for reconstructing the flight apparatus of ancestral crown birds and clarifying musculoskeletal modifications underlying the convergent origins of ratite flightlessness.