bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kaposi's sarcoma in a patient with pemphigus vulgaris mimicking exacerbation of pemphigus
Authors: Balighi Kamran , Ghiasi Maryam , Aryanian Zeinab , Nikyar Zahra , Hatami Parvaneh 
Published: April 2023

AbstractBackgroundKaposi's sarcoma (KS) is a rare multifocal angiogenic tumor often seen in immunocompromised setting such as acquired immunodeficiency syndrome (AIDS) or organ transplantation recipients. Pemphigus vulgaris (PV) is a rare blistering disorder with mucocutaneous involvement for which immunosuppressive therapy has long been the core of treatment. Iatrogenic form of KS has been reported infrequently in pemphigus patients as a result of long‐term immunosuppressive therapy.CaseWe describe a 39‐year‐old male patient with confirmed diagnosis of PV who developed KS after receiving immunosuppressive agents for his pemphigus. KS was initially localized to the oral cavity with features mimicking exacerbation of his pemphigus.ConclusionThis interesting case of KS suggests that dermatologists visiting patients with pemphigus with discomfort in the oral cavity should have a high degree of awareness and consider other differential diagnoses along with merely an exacerbation of PV.
Throughput and error probability improvement in downlink communication based on MIMO‐NOMA using reconfigurable intelligent surface (RIS)
Authors: Ravi M. , Sheikh Tasher Ali , Bulo Yaka 
Published: April 2023

SummaryThe user far from the base station (BS) can decode the signal via direct transmission or a relay network, but it cannot achieve higher throughput because of its high error probability. The MIMO‐NOMA‐Relay networks are replaced by MIMO‐NOMA‐RIS to achieve higher throughput in the proposal. The MIMO‐NOMA‐RIS sends a superimposed signal to the receiver using a multiple RIS beam scanning algorithm. They can improve the strength of the signal as well as improve the throughput and reduce the probability of error. As more reflecting surface area increases, the strength of the beam‐forming signal also increases, which means that the user could receive more signal strength than the direct transmission, amplify and forward (A&F) relay network. In multi‐user case, use the max–min power control algorithm (MMPCA) to allocate optimum power to a weaker channel strength user and achieve an optimum result. Method 1 used a single user with RIS to find the system equations. In both single‐user and multi‐user scenarios, we use MIMO‐NOMA‐RIS. Our proposed method's complexity is low because of its simplicity. In our proposed method, the MMPCA is used for optimum power allocation, and the resulting non‐convex function is converted into a convex one by using successive convex approximations. The result section shows that the RIS achieved the highest throughput and the lowest probability of error.
The ENSO cycle and forecastability of global inflation and output growth: Evidence from standard and mixed‐frequency multivariate singular spectrum analyses
Authors: Reza Yeganegi Mohammad , Hassani Hossein , Gupta Rangan 
Published: April 2023

AbstractIn this paper, the role of the El Niño‐Southern Oscillation (ENSO), measured by the Equatorial Southern Oscillation Index (EQSOI), is used to formally forecast the inflation and GDP growth rates of the United States, advanced (excluding the United States) and emerging countries, as well as the world economy (barring the United States). We rely on univariate and multivariate singular spectrum analyses (SSA), as well as mixed‐frequency version of the latter since the EQSOI is monthly, while GDP is available only at quarterly frequency unlike monthly inflation rates. We find statistically significant evidence of the ability of the EQSOI in forecasting inflation and GDP growth rates of the four economic blocs, though there are exceptions in terms of forecasting gains associated with inflation rate of emerging economies and the growth rate of the United States. Our results have important implications for policymakers.
Seed type and origin‐dependent seedling emergence patterns in Danthonia californica, a species commonly used in grassland restoration
Authors: Jones S. Holden , Reed Paul B. , Roy Bitty A. , Morris William F. , DeMarche Megan L. 
Published: April 2023

AbstractDanthonia californica Bolander (Poaceae)is a native perennial bunchgrass commonly used in the restoration of prairie ecosystems in the western United States. Plants of this species simultaneously produce both chasmogamous (potentially outcrossed) and cleistogamous (obligately self‐fertilized) seeds. Restoration practitioners almost exclusively use chasmogamous seeds for outplanting, which are predicted to perform better in novel environments due to their greater genetic diversity. Meanwhile, cleistogamous seeds may exhibit greater local adaptation to the conditions in which the maternal plant exists. We performed a common garden experiment at two sites in the Willamette Valley, Oregon, to assess the influence of seed type and source population (eight populations from a latitudinal gradient) on seedling emergence and found no evidence of local adaptation for either seed type. Cleistogamous seeds outperformed chasmogamous seeds, regardless of whether seeds were sourced directly from the common gardens (local seeds) or other populations (nonlocal seeds). Furthermore, average seed weight had a strong positive effect on seedling emergence, despite the fact that chasmogamous seeds had significantly greater mass than cleistogamous seeds. At one common garden, we observed that seeds of both types sourced from north of our planting site performed significantly better than local or southern‐sourced seeds. We also found a significant seed type and distance‐dependent interaction, with cleistogamous seedling emergence peaking approximately 125 km from the garden. These results suggest that cleistogamous seeds should be considered for greater use in D. californica restoration.
Effects of Ambient Temperature on the Recognition and Preferences for Host Song Pulse-rate by the Acoustic Parasitoid FlyOrmia ochracea
Authors: Jirik Karina J. , Dominguez Jimena A. , Abdulkarim Iya , Glaaser Johanna , Stoian Emilia , Almanza Luis J. , Lee Norman 
Published: April 2023

AbstractReceivers of acoustic communication signals evaluate signal features to correctly identify conspecifics. Environmental variation such as changes in the ambient temperature can alter signal features that may render species recognition a challenge. In field crickets, song temporal features evaluated for species recognition vary with temperature, and the intended receivers of these signals exhibit signal preferences that are temperature-coupled to maintain effective communication. Whether eavesdroppers of communication signals exhibit similar temperature-coupled preferences is unknown. Here, we investigate whether the parasitoid flyOrmia ochracea, an eavesdropper of cricket calling songs, exhibit song pulse rate preferences that are temperature-coupled. We use a high-speed treadmill system to record walking phonotaxis at three ambient temperatures (21, 25, and 30 °C) in response to songs that varied in pulse rates (20 to 90 pulses per second). Total walking distance, peak steering velocity, angular heading, and the phonotaxis performance index varied with song pulse rates and were affected by ambient temperature. The peak of phonotaxis performance index preference functions became broader and exhibited a “high-pass” shape, shifting to higher pulse rate values at higher temperatures. Temperature related changes in cricket songs between 21-30 °C will not drastically affect the ability of flies to recognize cricket calling songs.
A nurse‐led comprehensive geriatric assessment intervention in primary care: A feasibility cluster randomized controlled trial
Authors: Lyndon Helen , Latour Jos M. , Marsden Jonathan , Kent Bridie 
Published: April 2023

AbstractAimTo determine the feasibility of a nurse‐led, primary care‐based comprehensive geriatric assessment (CGA) intervention.DesignA feasibility cluster randomized controlled trial.MethodsThe trial was conducted in six general practices in the United Kingdom from May 2018 to April 2020. Participants were moderately/severely frail people aged 65 years and older living at home. Clusters were randomly assigned to the intervention arm control arms. A CGA was delivered to the intervention participants, with control participants receiving usual care. Study outcomes related to feasibility of the intervention and of conducting the trial including recruitment and retention. A range of outcome measures of quality of life, function, loneliness, self‐determination, mortality, hospital admission/readmission and number of prescribed medications were evaluated.ResultsAll pre‐specified feasibility criteria relating to recruitment and retention were met with 56 participants recruited in total (30 intervention and 26 control). Retention was high with 94.6% of participants completing 13‐week follow‐up and 87.5% (n = 49) completing 26‐week follow‐up. All outcome measures instruments met feasibility criteria relating to completeness and responsiveness over time. Quality of life was recommended as the primary outcome for a definitive trial with numbers of prescribed medications as a secondary outcome measure.ConclusionIt is feasible to implement and conduct a randomized controlled trial of a nurse‐led, primary care‐based CGA intervention.ImpactThe study provided evidence on the feasibility of a CGA intervention for older people delivered in primary care. It provides information to maximize the success of a definitive trial of the clinical effectiveness of the intervention.Patient or Public ContributionPatient and public representatives were involved in the study design including intervention development and production of participant‐facing documentation. Representatives served on the trial management and steering committees and, as part of this role, interpreted feasibility data. ISRCTN Number: 74345449.
Light therapy in insomnia disorder: A systematic review and meta‐analysis
Authors: Chambe Juliette , Reynaud Eve , Maruani Julia , Fraih Elise , Geoffroy Pierre A. , Bourgin Patrice 
Published: April 2023

SummaryIn the management of insomnia, physicians and patients are seeking alternative therapeutics to sleeping pills, in addition to sleep hygiene and cognitive behavioural therapy. Bright light therapy (LT) has proven its efficacy in circadian and mood disorders. We conducted a systematic literature review and meta‐analysis according to Cochrane and PRISMA guidelines and using the databases Medline, Cochrane, and Web of Science, with a special focus on light therapy and insomnia. Twenty‐two studies with a total of 685 participants were included, five of which with a high level of proof. Meta‐analysis was performed with 13 of them: light therapy for insomnia compared with control conditions significantly improved wake after sleep onset (WASO: SMD = −0.61 [−1.11, −0.11]; p = 0.017; weighted difference of 11.2 min ±11.5 based on actigraphy, and SMD = −1.09 [−1.43, −0.74] (p < 0.001) weighted difference of −36.4 min ±15.05) based on sleep diary, but no other sleep measures such as sleep latency, total sleep time (TST), or sleep efficiency. Qualitative analysis of the review showed some improvement mainly in subjective measures. Morning light exposure advanced sleep–wake rhythms and evening exposure led to a delay. No worsening was observed in objective nor subjective measures, except for TST in one study with evening exposure. A light dose–response may exist but the studies’ heterogeneity and publication bias limit the interpretation. To conclude, light therapy shows some effectiveness for sleep maintenance in insomnia disorders, but further research is needed to refine the light parameters to be chosen according to the type of insomnia, in the hope of developing personalised therapeutics.
The role of policy narrators during crisis: A micro‐level analysis of the sourcing, synthesizing, and sharing of policy narratives in rural Texas
Authors: Hand Mark C. , Morris Megan , Rai Varun 
Published: April 2023

AbstractHow do policymakers respond to crises? The Narrative Policy Framework (NPF) answers this question by focusing on the contest over policy narratives. This paper focuses on the individuals constructing those policy narratives, conceptualizing them as policy narrators. Using a case study approach, we analyze seven counties located in a major oil and gas formation in Texas, which in early 2020 faced both an oil bust and the onset of COVID‐19. We explore four sets of propositions about how policy narrators source, synthesize, and share their policy narratives. We find that while their narratives vary, the structure of those narratives is similar; their backgrounds shape how they source narratives, and they tailor their levels of narrative breach to the action (or inaction) they hope for. They avoid casting other local actors as villains, place their audience as the hero, and situate themselves as either supporting or a member of that audience, stressing their common ties. From these findings, we put forward a working definition of policy narrators, identify how they fit into the NPF, and discuss how they relate to other types of policy actors, including policy entrepreneurs.
Dataset S1 from Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications
Authors: Vasudevan Divya , Hickok Jason R. , Bovee Rhea C. , Pham Vy , Mantell Lin L. , Bahroos Neil , Kanabar Pinal , Cao Xing-Jun , Maienschein-Cline Mark , Garcia Benjamin A. , Thomas Douglas D. 
Published: April 2023

<p>GO terms associated with ÃƒÂ¢Ã‹â€ Ã¢â€žÂ¢NO-regulated genes</p>
Supplementary Method, Supplementary Tables, and Supplementary Figures from Photodynamic Therapy Synergizes with Irinotecan to Overcome Compensatory Mechanisms and Improve Treatment Outcomes in Pancreatic Cancer
Authors: Huang Huang-Chiao , Mallidi Srivalleesha , Liu Joyce , Chiang Chun-Te , Mai Zhiming , Goldschmidt Ruth , Ebrahim-Zadeh Neema , Rizvi Imran , Hasan Tayyaba 
Published: April 2023

<p>(i) Supplementary Methods 1.	Synthesis of L-BPD and L-IRI via freeze-thaw extrusion method 2.	Pharmacokinetics and biodistribution of L-BPD and L-IRI 3.	In-vitro quantification of changes in ABCG2 expression using immunofluorescence 4.	Ultrasound Imaging 5.	Histology and immunofluorescence of tumor samples 6.	Quantification of H&E and immunofluorescence biomarkers 7.	Determination of Synergism (ii) Supplementary Tables Supplementary Table S1. Comparison of PDT and irinotecan doses used in this study versus in clinic Supplementary Table S2. List of antibodies used for immunofluorescence Supplementary Table S3. The synergistic effect of combination PDT and L-IRI Supplementary Table S4. Physical parameters of L-BPD and L-IRI (iii) Supplementary Figures and Legends Supplementary Fig. S1. Treatment schedule and longitudinal monitoring of PanCa tumors in vivo Supplementary Fig. S2. Sub-cytotoxic PDT leads to decreased levels of ABCG2 and increased intracellular irinotecan in AsPC-1 cells Supplementary Fig. S3. Tumor growth kinetics of MIA PACa-2 and AsPC-1 in vivo Supplementary Fig. S4. Change in mouse body weight after combination treatment</p>
Supplementary Table 1 and Supplementary Figures 1 through 6 from <i>CSN1</i> Somatic Mutations in Penile Squamous Cell Carcinoma
Authors: Feber Andrew , Worth Daniel C. , Chakravarthy Ankur , de Winter Patricia , Shah Kunal , Arya Manit , Saqib Muhammad , Nigam Raj , Malone Peter R. , Tan Wei Shen , Rodney Simon , Freeman Alex , Jameson Charles , Wilson Gareth A. , Powles Tom , Beck Stephan , Fenton Tim , Sharp Tyson V. , Muneer Asif , Kelly John D. 
Published: April 2023

<p>Supplementary Table 1. A)Patient details for Fresh Frozen test cohort, B) Patient details for validation cohort. Supplementary Figure 1. APOBEC mutation fraction of across multiple cancer types. Supplementary Figure 2. DNA methylation. Supplementary Figure 3. Candidate PeCa driver mutations. Supplementary Figure 4. Schematic of FAT1 is shown with locations of mutations and ethylation states of PeCa and normal penile tissue across the canonical FAT1 gene. Supplementary Figure 5. A) Example plot of Copy Number Alterations (CNA) in penile cancers, 450K methylation profiles for penile cancer and normal squamous epithelium, and output from GISTIC showing the frequency and significance of CNAs.</p>
Supplementary Fig S5 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[<sup>18</sup>F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H. 
Published: April 2023

<p>200 mg/kg gemcitabine affect growth of A549 xenografts.</p>
Supplementary Fig S3 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[<sup>18</sup>F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H. 
Published: April 2023

<p>TS and hENT1 expression are not altered 6 h after gemcitabine.</p>
Effectiveness of laparoscopic appendectomy over open appendectomy in a tertiary care centre: a retrospective study
Authors: Akshitha Gardas , Venkata Reddy Morthala , Ananthula Anusha 
Published: April 2023

Background: Acute abdomen is the most common surgical clinical entity. Appendectomy is the treatment of choice for acute appendicitis. It can be done by open or laparoscopic method. Laparoscopic appendectomy gives a better evaluation of the peritoneal cavity than that obtained by open approach and also facilitates other differential diagnosis.
Methods: Patients admitted under surgical unit from December 2020 to June 2022, at Mamata Medical College and Hospital, Khammam. A study was carried out on 100 patients were admitted with 50 patients undergoing laparoscopic appendectomy and the remaining 50 patients undergoing open appendectomy. ln both study groups the outcome was assessed based on the intra operative finding, operative time, post-operative recovery, post-operative complications, and length of hospital stay.
Results: Findings of the patients undergoing open and laparoscopic appendectomy were compared and recorded. After analysing the data, there were significant differences between the two procedures with laparoscopic appendicectomy being better in respect to post operative pain perception, duration of analgesics used in days, postoperative infection, postoperative bleeding, post operative duration of hospital stay days and return to normal work in days with p value being significant.
Conclusions: The laparoscopic appendicectomy was better than open appendicectomy with respect to pain score, lesser use of analgesics, post operative complications like vomiting, ileus and wound infection rate. Only drawback of laparoscopic appendicectomy was with the duration of surgery. Overall laparoscopic appendicectomy is better than open appendicectomy in selected patients with acute/recurrent appendicitis.
An Auto Ethnographic Study on Communicative Approach in Teaching English Syntax in a University Context
Authors: Abdullah Abdullah , Noni Nurdin , Basri Muhammad , Djirong Agussalim 
Published: April 2023

This research employed an auto ethnographic study. It is a method used to describe the journey of the researcher in teaching English Syntax for three years in academic years 2015 to 2017. The problem in this research is how the lecturer implemented the communicative approach in teaching English Syntax in an Indonesian Higher Education Context. The Method used in this research is qualitative method. The subject of this research was the students and the lecturer of English department, Faculty of Language and Literature, Makassar State University. The instrument of the research was interview and auto ethnography reflection (lecturer personal reflection). Technique of the data collection used individual in-depth interview. The result of the data analysis indicated that the implementation of the communicative approach in teaching English Syntax run well because the students felt satisfy to join the class, from the class start until the end. The implementation was divided into three steps. The first is preparation; the lecturer has already prepared the teaching material well, the learning objective, and teaching method and strategy. The second is implementation the communicative approach in teaching English Syntax, and the third is evaluation. The all of the steps are run well in teaching English Syntax through the communicative approach. It can be concluded that teaching English Syntax through communicative approach was very good and successful, and get a good impact for the students in improving their language knowledge and skills. Keywords: an auto ethnographic study, Syntax, and communicative approach
Smart-Phone Assisted Language Learning in a Public University in Saudi Arabia
Authors: Mohamed Karem Abdelatif , Halim Tanzina 
Published: April 2023

The present study tried to investigate EFL teachers' and learners’ facilities regarding smartphone-assisted language learning (SALL) in the Faculty of Languages and Translation, King Khalid University (KKU), Saudi Arabia, including their attitudes, perceptions, levels of proficiency, and challenges they experienced. The study also pursued to inspect whether EFL teachers’ experiences have any significant influence on their facility of SALL. Investigation data was composed of (45) EFL teachers and (68) EFL learners. Two questionnaires were used to collect data. Some statistical analyses were used. The results showed EFL teachers' and learners’ positive perceptions of SALL. Participants stated that (SALL) is beneficial and has supported and enhanced EFL teaching and learning. Most EFL teachers said they needed more skills to advance SALL activities and mentioned some challenges they confronted. The results also indicated significant differences among participants’ SALL facility based on their professional development and teaching experiences, but no differences based on their gender were found. These results also showed that emphasizing professional development in SALL for KKU EFL teachers could promote greater proficiency and the facility to overcome challenges. The study concluded by providing recommendations on advancing SALL implications and suggestions. Keywords: EFL Learners, EFL Teachers, Facility, Implication, Smartphones