bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decreased Expression of EP3 Receptor mRNA in the Brain of Mouse
Model of Autism Spectrum Disorder
Authors: Anggadiredja Kusnandar , Kurniati Neng Fisheri , Kasai Atsushi , Hashimoto Hitoshi 
Published: April 2023

Background:
Accumulating evidence has implicated the role of neuroinflammation in the pathology of autism spectrum disorder (ASD), a neurodevelopmental disorder.

Objectives:
To investigate the expression of prostaglandin EP3 (EP3) receptor mRNA in the brain of ASD mouse model.

Methods:
Pregnant mice were injected with valproic acid (VPA) 500 mg/kg intraperitoneally at 12.5 d gestation. The offspring were tested at the age of 5-6 weeks old for their social interaction behav-ior. Each mouse was assessed for prostaglandin EP3 receptor expression in the prefrontal cortical, hippocampal and cerebellar areas one day after the behavioral test.

Results:
Compared to the naive, mice born to dams treated with VPA demonstrated a significantly shorter duration of sniffing behavior, a model of social interaction. Results further showed that the expression of EP3 receptor mRNA was significantly lower in all three brain regions of the mice born to VPA-treated dams.

Conclusion:
The present study provides further evidence of the relevance of the arachidonic acid cascade as an essential part of neuroinflammation in the pathology of ASD.
How People Use Web-Based Parenting Information to Support Others in Their Social Circle: Qualitative Descriptive Study
Authors: El Sherif Reem , Pluye Pierre , Paquet Virginie , Ibekwe Fidelia , Grad Roland 
Published: April 2023

Background
Almost two-thirds of the North American population have searched for health information on the web, and the majority report searching on behalf of someone else in their social circle, a phenomenon referred to as proxy seeking. Little is known about how proxy seekers use web-based health information and the outcomes they experience.

Objective
The main aim of this study was to explore why proxy seekers used a parenting website on behalf of parents in their social circle and the outcomes they reported.

Methods
A qualitative descriptive study was conducted in the context of a partnership with a web-based parenting resource to explore the contexts and motivations for proxy web-based health information seeking, use of information, and subsequent outcomes. A total of 14 participants who self-identified as family members, friends of parents of young children, or professionals who worked with young children were interviewed, and a thematic analysis was conducted.

Results
The following 4 reasons for proxy seeking were uncovered: for reassurance, out of personal curiosity, as part of a professional role, or following an explicit request from the parents. Information was used to provide informational support for parents or material support for a child. Positive outcomes of using the information and some of the resulting interpersonal tensions were described.

Conclusions
This study provides an in-depth look at proxy seeking behavior and outcomes among users of a web-based parenting resource.
Efficacy and Safety of Home-Based Cardiac Telemonitoring Rehabilitation in Patients After Transcatheter Aortic Valve Implantation: Single-Center Usability and Feasibility Study
Authors: Ashikaga Kohei , Doi Shunichi , Yoneyama Kihei , Suzuki Norio , Kuwata Shingo , Koga Masashi , Takeichi Naoya , Watanabe Satoshi , Izumo Masaki , Kida Keisuke , Akashi Yoshihiro J 
Published: April 2023

Background
No consensus exists on the efficacy of home-based cardiac rehabilitation (CR) in patients who have undergone transcatheter aortic valve implantation (TAVI). Additionally, there are no reports on home-based cardiac telemonitoring rehabilitation (HBTR) in patients after TAVI.

Objective
We aimed to investigate the efficacy of HBTR in patients who have undergone TAVI.

Methods
This single-center preliminary study introduced HBTR to patients after TAVI, and the efficacy outcomes of the rehabilitation method were compared to that of a historical control cohort. The historical control cohort (control group) consisted of 6 consecutive patients who underwent ordinary outpatient CR after TAVI from February 2016 to March 2020. Patients who participated in the HBTR program were only recruited after the TAVI procedure and before discharge between April 2021 and May 2022. In the first 2 weeks after TAVI, patients underwent outpatient CR and were trained using telemonitoring rehabilitation systems. Thereafter, patients underwent HBTR twice a week for 12 weeks. The control group performed standard outpatient CR at least once a week for 12 to 16 weeks. Efficacy was assessed using peak oxygen uptake (VO2) prior to and after CR.

Results
Eleven patients were included in the HBTR group. All patients underwent 24 HBTR sessions during the 12-week training period, and no adverse events were observed. The control group participants performed 19 (SD 7) sessions during the training period, and no adverse events were observed. Participants in the HBTR and control groups had a mean age of 80.4 (SD 6.0) years and 79.0 (SD 3.9) years, respectively. In the HBTR group, preintervention and postintervention peak VO2 values were 12.0 (SD 1.7) mL/min/kg and 14.3 (SD 2.7) mL/min/kg (P=.03), respectively. The peak VO2 changes in the HBTR and control groups were 2.4 (SD 1.4) mL/min/kg and 1.3 (SD 5.0) mL/min/kg (P=.64), respectively.

Conclusions
Home-based CR using a telemonitoring system is a safe outpatient rehabilitation method. Its efficacy is not inferior to that of standard CR in patients who have undergone TAVI.

Trial Registration
Japan Registry of Clinical Trials jRCTs032200122; https://jrct.niph.go.jp/latest-detail/jRCTs032200122
Seeing Muslim Men and Women Hermeneutically: A Liberal-Feminist Study on Amina Wadud’s Qur’an Exegesis
Authors: Ariesita Dahlia Kartika , Adhitya Galant Nanta 
Published: April 2023

Gender inequality became one of the important issues in the US as it intersects with other societal aspects, one of which is religion. In the last century, the US has seen a fast-growing number of believers in Islam, despite its unequal practices based on gender. American Muslim women are not only treated differently due to religious beliefs but also to racial backgrounds. The emergence of Amina Wadud, a female Imam with an African-American background, brings new thoughts on the position of women in Islam. Employing the Post-Nationalist approach combined with Rosemarie Tong’s liberal feminism theory, this article analyzes Wadud’s Qur’an and Women: Re-reading the Sacred Text from a Woman’s Perspective to reveal her thinking in becoming a female Imam in the US, as well as her fights against injustices towards Muslim women. It finds that her background as an African-American woman, a second class in American society, pushes her to put women’s rights in Islam forward, which are not consistent in the Qur’an. She re-interprets it with the hermeneutic method, putting women and men in the same position. While her pro-faith determination for equality drives her to overcome the rejection from the American Muslim community when she became an imam in a mixed congregation of Friday prayers.
Estudio de validez y confiabilidad del Cuestionario de Gratitud-6 (GQ-6) en México
Authors: Quezada Berumen Lucía 
Published: April 2023

Las investigaciones han sugerido que las personas agradecidas son más felices, enérgicas y tienen mayor esperanza de tener experiencias positivas. A pesar de que el GQ-6 es un instrumento ampliamente utilizado para evaluar la gratitud, su estructura factorial no ha sido explorada en población mexicana. El objetivo del presente estudio fue evaluar las propiedades psicométricas del GQ-6 en una muestra mexicana. Participaron 566 personas de población general de 18 a 67 años. El GQ-6 fue administrado junto con la Escala de Afecto Positivo y Afecto Negativo (PANAS) y el Test de Orientación Vital (LOT-R). Los resultados indicaron una estructura unifactorial con seis indicadores la cual mostró una buena bondad de ajuste y confiabilidad aceptable (α = .79); estos resultados se mantuvieron independientemente del sexo. Puede concluirse que el GQ-6 es un instrumento con buenas propiedades psicométricas para evaluar la disposición para experimentar gratitud en población mexicana.
Modelo para medir el retorno sobre la inversión en seguridad informática y de la información - ROSI
Authors: Angulo Rivera Christian 
Published: April 2023

The following work tries to propose across a quantitative correlation investigation, a model to measure the return on the investment in IT security ROSI in the SMEs of Colombia, allowing hereby that the managers, leaders of technology and security, should have the necessary tools to determine in an objective way how to prioritize the investments, thinking always about the economic and operative well-being of the organization.
An important variable of this investigation is the understanding of the state in which they find the SMEs of Colombia in topics of IT security and of the information, since these topics are new due to the fact that scarcely they are starting listening to these terms, thanks to the quantity of news that relates to "Hackers" or losses of corporate information. In the city of Cali there is a great quantity of SMEs that are very focused on the development of their service or main function and do not have inside their radar a topic so delicate as it is that of the IT security and of the information.
Likewise, the aim is to make visible the security models that SMEs can use into account the advantages and disadvantages of their application. Although it is not mandatory for legally constituted organizations to implement security controls, there is a corporate responsibility for the delivery of an excellent product or service, which is only guaranteed if the information assets are correctly safeguarded.
Hidden and intangible costs generated due to lack of investment or planning in security investments are also presented. This allows SMEs to be aware that they can be victims of computer criminals or that losses can be generated due to the lack of training of their staff and all this due to the lack of implementation of controls, which ensure proper management on issues technological.
Modelo de análisis de la cultura organizacional en los sistemas de producción - operaciones
Authors: Vivares Jorge Andrés , Rivera Gabriel , Alzate Leonardo , Avella Lucía 
Published: April 2023

Organizational culture is a mental pattern that governs decision-making and people’s behavior, it also facilitates, or inhibits, distinctive capabilities development in organizations. In this paper we study organizational culture in production-operations systems, because phenomenon about culture could explain the system performance, and we prove there is a gap of knowledge in the state of the art about this topic based on a systematic literature review. Furthermore, the purpose of this work was to develop a theoretical framework to study organizational culture in production-operations systems. That framework provides several novelty propositions for further research.
Diseño de un Roadmap Empresarial para mejorar los procesos de la gestión documental de la secretaria de movilidad del distrito de Turbo Antioquia a través de Cloud Computing
Authors: Barrios Chaverra Geider , Cardona Román Diana Marcela 
Published: April 2023

The development context of the project is focused on making a Roadmap which establishes the ideal route to improve the document management processes of the Turbo Antioquia district mobility secretary, using Cloud Computing services.
The entity's problems are mainly due to the failures presented in the document and files management processes since it does not accomplish with the parameters of the Archives Law issued by the Ministry of ICT.
The methodology used in this study corresponds to descriptive applied research. To carry out the Roadmap, ten steps were taken into account, one of them was to know the current state of the document and file management processes (AS-IS), determine the desired or future states (TO-BE) through of activities aimed at closing the gaps, such as training administrative personnel or those in the area of document and archive management processes, taking into account the guidelines of the national government through the Ministry of ICT and international standards. Implement an information security system for the protection of information in the management of procedures.
The result of this project is to carry out the design of the Roadmap, outlining the established guidelines to meet the indicators that allow closing the gaps with the aim of improving the processes of the document management of the Mobility Secretary of the Turbo Antioquia District.
To achieve the results of this research, the business architecture approach was used through the design of a road map, whose in-depth analysis allows knowing the current state (AS-IS) of the entity's capabilities and processes, in the document management area. This linked to a set of strategies or particular activities in time for each problem presented with the objective of closing the gaps, as a method of solution to each problem presented. The proposed solution is known as the future state (TO-BE), where solutions are presented to the problems found in the document management processes. The main conclusion of the work was that the use of Cloud Computing in the document management process was found as a fundamental element of the new disruptive trends in IT management processes.
Deep generative learning helps extract ecological meaning from the complex three dimensional shapes of bird bills
Authors: Dinnage Russell , Kleineberg Marian 
Published: April 2023

Data on the three dimensional shape of organismal morphology is becoming
increasingly common. The availability of this data forms part of a new
revolution in high-throughput phenomics that promises to help understand
ecological and evolutionary processes that influence phenotypes at
unprecedented scales. However, in order to meet the potential of this
revolution we need new data analysis tools to deal with the complexity
and heterogeneity of large-scale phenotypic data such as that
represented by three dimensional shapes. In this study we explore the
potential of techniques derived from Artificial Intelligence research to
help organise and extract meaning from complex 3D data. Specifically, we
train a deep representational learning method known as DeepSDF, a type
of deep generative model, on a dataset of 3D scans of the bills of 2,020
bird species. The model is designed to learn a continuous vector
representation of 3D shapes, along with a ‘decoder’ function, that
allows the transformation from this vector space to the original 3d
morphological space. We find that that the latent vector representations
learned by the approach have morphological coherence in the sense that
movement along various directions in the latent space form smooth
continuous transformations in 3D morphological space, and that
particular directions are associated with discernible morphological
meaning (such as elongation, flattening, etc.). Learned latent vectors
also have ecological meaning as shown by their ability to predict the
trophic niche of the bird each bill belongs to with a high degree of
accuracy. Unlike existing 3D morphometric techniques, this method has
very little requirements for human supervised tasks such as landmark
placement, increasing it accessibility to labs with fewer labour
resources. It has fewer strong assumptions than alternative dimension
reduction techniques such as PCA. The computational requirements for
training the model, while substantial, is still within the reasonable
reach of most researchers, with a ~2000 shape model
taking just over 2 days to train on only a single current generation
consumer-level GPU. Once trained, 3D morphology predictions can be made
from latent vectors very computationally cheaply. Lastly, we present an
in development R package with an implementation of the model, with the
goal of making model training accessible to any researcher with access
to data and GPU computing resources.
Modeling lathe dynamic system in terms of estimated dampening coefficient of autocorrelation function of oscillations
Authors: Ignatyev Alexander Anatolevich , Nasad Irina Pavlovna , Nasad Tat'yana Gennadievna 
Published: April 2023

Part machining on the lathes with automated tools is a complex process that depends on the properties
of the lathe dynamic system. Oscillations in processing the main parts determine the dynamic quality of the lathes, quality of the surface layer and resistance of the cutting tool, therefore, it is necessary to identify the methods to control the operation mode. Increased efficiency of the process is provided by the forced cutting modes, which can lead to the deterioration of processing quality and premature wear of a cutting tool. Theoretical definition of rational cutting modes causes certain difficulties, so the experimental search for a solution to the problem is most urgent. In order to select rational cutting modes on the lathes and grinding machines, it is proposed to use the stability margin of the lathe dynamic system (DS), which should be determined from the transfer function of DS using the autocorrelation function (ACF) of oscillations. A condition for identification of the lathe DS is a preliminary identification of ACF, which can be implemented using oscillation records during cutting. Pre-filtering of oscillations is carried out to exclude low-frequency range containing frequencies caused by oscillations of lathe system elements and to save frequencies associated with the cutting process. Cut modes are assigned to the highest stability margin, which ensures high surface quality. There is an unambiguous ana-lytical relationship between the oscillation index and the damping coefficient of the ACF, which makes it possible to calculate the α coefficient, by the value of which it is possible to estimate the stability margin of the ET in different cutting modes and select the most appropriate one. Studying the lathe oscillations in processing high-precision parts makes it possible to control the technological mode, using the oscillation level as one of the indicators of its quality.
ХУДОЖНІЙ СВІТ ПРОЗИ СИДОНІЇ НИКОРОВИЧ 1910-Х РОКІВ
Authors: Антофійчук Володимир 
Published: April 2023

У статті вперше простежуються основні ідейно-тематичні та жанрово-стильові особливості прози за- бутої письменниці Сидонії Никорович (1888 – 1957) – активної учасниці та організаторки українського літературного процесу на Буковині та в Румунії, громадсько-культурної діячки, соратниці Ольги Кобилянської.
Художній світ письменниці розкривається у багатьох різножанрових творах: поезіях у прозі, новелах, оповіда- ннях, повістях тощо. У їх центрі – молода жінка, яка втілює найкращі риси тодішнього українського суспільства і в різний спосіб протистоїть тим соціальним, морально-психологічним і звичаєво-побутовим обставинам, які принижують її людську та національну гідність. Основна увага приділена аналізу повісті «Анничка», в якій протиставляються два світи – селянський і шляхетський, що свідчить про намагання письменниці зберегти й утривалити традиційні на- ціональні цінності, а також пояснює її закорінення в народницько-етнографічні традиції, характерні для українського письменства усього ХІХ століття. Однак під цим товстим покровом літературного консерватизму пробиваються потужні модерністичні паростки, що проявляються в сюжетно-композиційній організації твору, яка ґрунтується на паралелі символізму станового одягу та станової й національної самоідентифікації, міфологічно-ритуальних світоуявленнях героїв тощо.
Стверджується, що наративні стратеґії прози Сидонії Никорович виразно детерміновані моральними засадами, основоположними аксіологічними уявленнями про шлюб, моральні норми і християнські традиції. За стилістичними та ідейно-естетичними особливостями повість «Марія» Сидонії Никорович близька до творів Ольги Кобилянської «В неділю рано зілля копала» і «Земля» та інших модерністичних зразків української прози. В основі повісті «Касандра» романтична історія про особисту драму заголовної героїні, спричинену заміжжям без любові. Однак проблемно- тематичний комплекс аналізованої прози, характер і спосіб його художньої реалізації виразно декларують специфічні риси неоромантичного художнього мислення Сидонії Никорович.
PELATIHAN PEMBUATAN HAND SANITIZER BERBASIS BAHAN ALAM UNTUK MENDUKUNG PROTOKOL KESEHATAN DI ERA PANDEMI COVID-19
Authors: Maharani Dina Kartika , Kusumawati Nita , Setiarso Pirim , Sanjaya IGM , Monica Maria , Samik Samik , Safitri Rizka Dwi , Nurzulla Weka Firda Rizki , Rhamdiyah Fastabiqul Khairati , Ramadanti Awanda Halida , Naulia Kaila , Lailiyah Nur 
Published: April 2023

Pandemi Covid-19 menuntut masyarakat untuk selalu menerapkan protokol kesehatan terutama jika berada di luar rumah atau saat berada di kerumunan. Salah satunya yang gencar disosialisaikan adalah mencuci tangan dengan sabun atau menggunakan hand sanitizer. Kebiasaan baru ini meningkatkan kebutuhan hand sanitizer yang tinggi di pasaran. Hand sanitizer yang sudah ada di pasaran umumnya realtif cukup mahal dan berbasis alkohol yang kurang ramah lingkungan. Oleh karena itu perlu diadakan pelatihan pembuatan hand sanitizer berbasis bahan alam sebagai bentuk edukasi kepada masyarakat untuk memperoleh hand sanitizer yang murah dan ramah lingkungan. Pelatihan diikuti oleh peserta yang mayoritas berdomisili di wilayah Driyorejo, Gresik. Tujuan diadakannya pelatihan ini adalah agar warga Driyorejo, Gresik yang mayoritas bekerja di bidang industri memiliki pengetahuan dan keterampilan untuk membuat hand sanitizer secara mandiri dari bahan yang mudah diperoleh di sekitar rumah. Bahan alam yang digunakan yaitu daun kemangi dan daun sirih, serta diberikan juga pelatihan untuk pembuatan hand sanitizer alkohol dalam sediaanspray dan gel. Kegiatan pelatihan dilakukan pada 4 September 2021 secara webinar, penyampaian materi dilakukan melalui Zoom. Pelatihan dilaksanakan dengan peserta sebanyak 87 orang. Kepada 20 peserta diberikan kesempatan untuk membuat hand sanitizer sendiri di rumah dengan mempraktikkan ilmu yang telah didapatkan dari pelatihan. Sebagai bahan evaluasi, peserta diwajibkan mengirimkan video saat proses pembuatan. Hasil evaluasi kegiatan pelatihan hand sanitizer menunjukkan bahwa masyarakat Driyorejo telah terampil membuat hand sanitizer alami maupun berbasis alkohol.