bluuebunny/crossref_metadata_2025_split huggingface dataset:
EKSTRAK BUAH DELIMA (Punica granatum L) SEBAGAI FORMULASI LIPSTIK
Authors: Yanty Yuska Novi , Hepiyansori Hepiyansori , Niarisesa Lisza 
Published: January 2025

Buah Delima (Punica granatum l) termasuk famili PunicaceaeÃƒâ€šÃ‚Â yang mengandung antosianin. Warna dari buah delima disebabkan oleh flavanoid yaitu antosianin. Antosianin merupakan pigmen yang dapat digunakan sebagai pewarna alami dan dapat menggantikan pewarna sintesis. Penelitian ini dilakukan untuk membuat sediaan lipstik dari ekstrak buah delima dan mengetahui pengaruh perbedaan konsentrasi ekstrak buah delima. Pembuatan ekstrak dilakukan dengan metode maserasi dengan menggunakan etanol 96% sebagai pelarut, kemudian pelarut dipekatkan dengan rotary evaporator sehingga diperoleh ekstrak buah delima. Komponen sediaan lipstik terdiri dari cera alba, vaselin alba, setil alkohol, carnauba wax, lanolin, propilen glikol, nipagin, oleum ricini, oleum rosae, serta penambahan ekstrak buah delima dengan konsentrasi 15%, 18%, dan 21%. Pengujian terhadap sediaan meliputi pemeriksaan mutu meliputi uji organoleptis, uji homogenitas, uji pH, uji titi lebur, uji stabilitas, dan uji iritasi. Sediaan lipstik yang dihasilkan mudah dioleskan dan homogen, sediaan tidak menyebabkan iritasi, stabil, bau khas, bentuk silinder, dan warna merah muda. Pengukuran pH rata-rata sediaan lipstik yang mengandung ekstrak buah delima dengan konsentrasi 15% : 4, 06%, : 3,68 dan 21% : 3,53. Titik lebur pada konsentrasi 15% : 59,2Ãƒâ€šÃ‚Â°C, 18%, : 58,5Ãƒâ€šÃ‚Â°C dan 21% : 57,6Ãƒâ€šÃ‚Â°C
ANALISIS LC-MS/MS SENYAWA METABOLITE EKSTRAK DAUN PUTAT (Planchonia valida) DAN PREDIKSI POTENSINYA SEBAGAI KANDIDAT OBAT ANTIKANKER
Authors: Dewi Tribuana Tungga , Bela Anisa , Prabawa Satria , Latief Madyawati , Tarigan Indra Lasmana 
Published: January 2025

Secondary metabolite compounds contained in plants are bioactive substances related to the chemical content in plants, so that some plants can be used as medicinal materials. Putat (Planchonia valida) is a medicinal plant that has bioactive compounds that have potential as anticancer. Compound analysis of LC-MS test results has been carried out which shows several metabolite compounds contained in putat. The method used is analyzing compounds obtained from LC-MS results, screening compounds using pchembl and chemspider websites. And using the pChEMBL webserver to find out the bioactivity of these compounds. The purpose of this study is to determine and predict the potential bioactivity of the compounds contained therein as new drug candidates. The results obtained from this study are metabolite compounds in putat have the potential as anticancer based on the screening results carried out using the pChEMBL webserver by looking at the highest pIC50 value, obtained the highest pIC50 value of 8.18 with target proteins namely Serine/threonin mTOR and Cholinesterase which are target proteins that have anticancer activity.
HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT HIPERTENSI MENGGUNAKAN KUESIONER HILL-BONE TERHADAP KUALITAS HIDUP PASIEN DI PUSKESMAS PEKAUMAN BANJARMASIN SELATAN
Authors: Safitri Sri Desi , Hartanto Dedi , Mulyani Tuty 
Published: January 2025

Hypertension is a disease that is the number one cause of death in the world every year. Based on measurements at ages ≥18 years, the highest hypertension prevalence data according to the province is South Kalimantan at 44.13%. One of the causes of the high prevalence of hypertension is due to low compliance in taking medication. Compliance is very necessary while undergoing hypertension treatment to reduce the impact and thus provide a good quality of life. The purpose of this study was to determine the relationship between the level of compliance using the Hill-Bone questionnaire on the quality of life of hypertensive patients at the Puskesmas Pekauman. This study used an observational method with a cross-sectional design to determine the picture of the level of compliance with the quality of life of hypertensive patients at the Puskesmas Pekauman. Data collection using the Hill-Bone questionnaire to determine adherence level and EQ-5D-5L questionnaire to determine patient's quality of life. The results of this study showed that of the 68 respondents, 3 people (4.40%) with a moderate level of compliance had a moderate quality of life, 59 people (86.80%) with a moderate level of compliance had a high quality of life and 6 people (8.8 %) with a high level of compliance have a high quality of life, which is obtained from Kendall's tau-B test, p-value = 0.000 < 0,05. It can be concluded that there is a significant relationship between compliance and quality of life in hypertension sufferers at the Puskesmas Pekauman.
MEKANISME KO-KEMOTERAPI EKSTRAK ROSELLA (Hibiscus sabdariffa. L) DENGAN DOXORUBICIN PADA SEL KANKER SERVIKS (HeLa) SECARA IN VITRO
Authors: Daud Intan , Hayu Nurani Laela , Bachri Moch. Saiful , Ariani Edityaningrum Citra , Ma’ruf Muhammad 
Published: January 2025

Cervical cancer caused by exposure to Human Papilloma Virus (HPV) through sexual intercourse can be treated with Doxorubicin. Doxorubicin shows side effects so it needs to be combined with co-chemotherapy. Rosella (Hibiscus sabdariffa L.) The main content of anthocyanins is cytotoxic to HeLa cells. The purpose of this study was to find co-chemotherapy combination of Doxorubicin and Rosella extract with apoptosis mechanism and Rosella antiproliferation.
The research method starts from the maceration process of Rosella petals using 96% ethanol. Cytotoxic test method, antiproliferation test, apoptosis, and combination test with MTT method using HeLa cells.
The result of cytotoxic test showed IC50 of Rosella extract was 32.3 ± 2.15 µg/mL and IC50 of Doxorubicin was 2.68 ± 0.09 µg/mL. The antiproliferation test results in the control cell doubling time of 28.25 ± 0.21 hours while the concentration of Rosella extract at levels of 32.3; 16.15; and 8.08 µg/mL doubling time of 53.23 ± 0.20 hours, 39.02 ± 0.19 hours and 46.74 ± 0.23 hours so that it shows the inhibition of cell multiplication growth. The IC results show the combination of 4.04 µg/mL Rosella Flower Extract and 2.67 µg/mL Doxorubicin which is 0.0013 can be interpreted as a very strong synergistic effect (0.0013 ≤ 0.1). So it can be concluded the combination of ethanol extract Rosella flowers has antiproliferation properties through the mechanism of delaying the doubling time.
СРАВНИТЕЛЬНЫЙ АНАЛИЗ РАБОТЫ ЭВОЛЮЦИОННЫХ АЛГОРИТМОВ ПРИ РЕШЕНИИ МНОГОКРИТЕРИАЛЬНОЙ ТРАНСПОРТНОЙ ЗАДАЧИ БЕЗ ОГРАНИЧЕНИЙ
Authors: Белых М.А. , Баранов Д.А. , Барабанов В.Ф. 
Published: January 2025

проводится вычислительный эксперимент по решению многокритериальной транспортной задачи с использованием набора эволюционных алгоритмов, в числе которых генетический алгоритм, алгоритм муравьиной колонии и алгоритм пчелиной колонии. В исследовании используется 10000 различных постановок задачи, каждая из которых состоит из квадратной матрицы смежности размерностью от 10х10 до 20х20. Каждая из этих постановок решалась с использованием 39 вариаций каждого из алгоритмов. Каждым алгоритмом было выполнено по 60 итераций с 60 особями в составе. Основная цель вычислительного эксперимента заключалась в оценке производительности и качества решений, предоставляемых этими алгоритмами, а также в выявлении их преимуществ и недостатков их применения в различных условиях в рамках решения многокритериальной транспортной задачи без ограничений. Результаты экспериментов показывают, что каждый из алгоритмов обладает уникальными характеристиками и может быть предпочтителен в зависимости от специфики задачи и требований к вычислительным ресурсам. Проведенный анализ предоставляет ценную информацию для дальнейших исследований и практического применения метаэвристических методов в решении, в частности, комбинаторных задач оптимизации
this paper presents a computational experiment on solving a multicriteria transportation problem using a set of evolutionary algorithms, including a genetic algorithm, an ant colony algorithm, and a bee colony algorithm. The study uses 10,000 different problem statements, each consisting of a square adjacency matrix with dimensions from 10x10 to 20x20. Each of these statements was solved using 39 variations of each algorithm. Each algorithm performed 60 iterations with 60 individuals in its composition. The main goal of the computational experiment was to evaluate the performance and quality of solutions provided by these algorithms, as well as to identify their advantages and disadvantages of their application in various conditions within the framework of solving a multicriteria transportation problem without constraints. The experimental results show that each of the algorithms has unique characteristics and can be preferable depending on the specifics of the problem and the requirements for computing resources. The conducted analysis provides valuable information for further research and practical application of metaheuristic methods in solving, in particular, combinatorial optimization problems
СОВЕРШЕНСТВОВАНИЕ СИСТЕМЫ РАЗВАРКИ КОНТАКТОВ В СЛУЧАЕ ИЗГОТОВЛЕНИЯ ИНТЕГРАЛЬНЫХ МИКРОСХЕМ
Authors: Долженков С.В. , Звягинцева А.В. , Меньшикова Т.Г. 
Published: January 2025

приведено исследование процессaультразвуковой микросварки проводников методом «клин – клин». Приведена методика исследования микросоединения проволоки с контактными площадками кристалла и внешними выводами. Было проведено определенное сравнение прочности соединений, сформированных при использовании двух различных мощностей (на траверсе и на кристалле). Установлены параметры, при которых зафиксирована максимальная прочность микросварных соединений на разных уровнях мощности ультразвуковая сварка при стандартной частоте ультразвуковых колебаний. Использован метод ультразвуковой сварки только «клин-клином». Ультразвуковая сварка методом клин-клин Au или Al проволокой - передовая технология сварки, обеспечивающая прочные соединения. Она применяется для сварки различных материалов, включая металлы, пластмассы и композиты. Этот метод обладает высокой скоростью сварки и исключает необходимость в клеевых соединениях. Тестирование на отрыв гарантирует надежность и соответствие стандартам сварных соединений. Определено, какое влияние имеет мощность УЗС на прочностные характеристики сварных соединений. Реализована оценка качества сварных сшивок в 3-х режимах: с увеличенным, нормализованным и со сниженным параметром мощности. Зафиксирован оптимальный режим разварки контактов, обеспечивающий прочность микросоединений
the article presents a study of the process of ultrasonic micro–welding of conductors by the "wedge - wedge" method. A technique for investigating the micro-connection of a wire with crystal contact pads and external terminals is presented. A comparison of the strength of the compounds obtained at the two capacities used (on the traverse and on the crystal) is determined. The parameters were obtained at which the greatest strength of micro-welded joints was observed at various ultrasound capacities at the standard frequency of ultrasonic vibrations. In this work, the ultrasound method is used only "wedge-wedge". Ultrasonic wedge-wedge welding with Au or Al wire is an advanced welding technology that ensures strong connections. It is used for welding various materials, including metals, plastics and composites. This method has a high welding speed and eliminates the need for adhesive joints. Separation testing guarantees reliability and compliance with the standards of welded joints. It is determined what effect the power of the ultrasonic circuit has on the strength characteristics of welded joints. The assessment of the quality of welded joints in 3 modes is implemented: with increased, normalized and with reduced power parameter. The optimal contact welding mode has been fixed, which ensures the strength of the micro-connections
Mengungkap Persepsi Masyarakat Terhadap Tingkat Kepercayaan Pengelolaan PAD dan APBD di Kalimantan Tengah
Authors: Malinda Okta , Lampang Muhammad Aji , Ramadhan Muhammad Abshar Noer , Pratama Pratama , Pratama Mar’elfan Hadi , Octaviani Theresia , Andrenossa Glenn 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui persepsi masyarakat terhadap tingkat kepercayaan pengelolaan PAD dan APBD di Provinsi Kalimantan Tengah. Sampel dalam penelitian ini adalah masyarakat Provinsi Kalimantan Tengah dengan usia 20 tahun ke atas. Pengumpulan data dilakukan dengan metode purposive sampling dengan menggunakan instrumen kuesioner yang sesuai dengan kriteria sampel. Teknik pengolahan data yang digunakan adalah analisis statistik deskriptif dengan menggunakan IBM SPSS S. Berdasarkan hasil penelitian terkait variabel persepsi dan variabel kepercayaan, rata-rata jawaban responden menunjukkan hasil yang netral. Netralitas ini mungkin disebabkan oleh rasa segan atau kekhawatiran masyarakat dalam mengekspresikan pandangan mereka secara terbuka mengenai pengelolaan PAD dan APBD, yang dapat mencerminkan kehati-hatian dalam berpendapat mengenai isu-isu yang berhubungan dengan pemerintah daerah. Selain itu, diketahui bahwa persepsi masyarakat memiliki pengaruh yang signifikan terhadap tingkat kepercayaan terhadap pengelolaan PAD dan APBD di Kalimantan Tengah dengan tingkat signifikansinya sebesar 79,60%.
KONSEP EVALUASI PENDIDIKAN DALAM PERSPEKTIF ISLAM
Authors: Imam Maulana Hidayat  , Fitri Hilmiyati  
Published: January 2025

Evaluasi dalam Islam bukan sekadar pengukuran hasil belajar, tetapi juga sebagai alat untuk menilai perkembangan karakter dan hubungan seseorang dengan Tuhannya. Tujuan penelitian ini untuk mengetahui konsep evaluasi pendidikan dalam perspektif Islam. Riset ini menggunakan metode penelitian kualitatif kajian pustaka, dimana peneliti akan mencari sumber data dari hasil wawancara dengan berbagai sumber dan menggali informasi berdasarkan studi dokumentasi. Hasil dari penelitian ini adalah yang pertama evaluasi pendidikan sebagai tindakan atau proses untuk menemukan atau menentukan nilai suatu hal, atau dapat juga diartikan sebagai proses penilaian terhadap segala sesuatu yang terkait dengan objek yang dinilai. Yang kedua menurut Al-Qur'an, evaluasi pendidikan memiliki peran yang sangat penting dalam kehidupan manusia. Al-Qur'an memberikan perhatian khusus pada pentingnya penilaian terhadap segala sesuatu, termasuk penilaian diri, proses pembelajaran, dan hasil pendidikan. Yang ketiga dalam Al-Qur’an terminologi evaluasi pendidikan terdapat beberapa makna dengan mengacu kepada makna kalimat yaitu Al-Hisab, Al-Bala. Yang keempat sistem evaluasi yang dikembangkan dalam oleh Allah SWT dan Rasul-Nya berimplikasikan paedagogis.
Kata Kunci : Implementasi Kompetensi Spiritual; Kompetensi Sosial; Karakter Siswa
The Effect of Transformational Leadership and Career Management on Organizational Commitment with Job Satisfaction as an Interverning Variable
Authors: Siregar Aisyah Huwaida , Budi Winarso Anjar Prihantoro 
Published: January 2025

This study aims to analyse the effect of transformational leadership, career management on organisational commitment with job satisfaction as an interverning variable. The population of the study is active civil servants in the BP2MI environment, totalling 884 people (data as of December 2023). Determination of the number of research samples using the Slovin formula due to the limited and reachable population of 275 people. The sampling method used non-probability sampling with purposive sampling technique. This study uses a Structural Equation Model (SEM) approach with a measurement model using the Smart PLS version 3.2.9 programme. The results showed that Transformational Leadership had no significant direct influence on Organisational Commitment at BP2MI. Transformational Leadership had a significant direct influence on employee Job Satisfaction at BP2MI. Career Management had a significant direct influence on employee Job Satisfaction at BP2MI. Job Satisfaction had a significant direct influence on Organisational Commitment of employees at BP2MI. Job Satisfaction can mediate the effect of Transformational Leadership on Organisational Commitment at BP2MI. Job Satisfaction can mediate the effect of Career Management on Organisational Commitment at BP2MI.
The Orbits of Uranus, Its Satellites and Rings, the Gravity Field of the Uranian System, and the Orientation of the Poles of Uranus and Its Satellites*
Authors: Jacobson Robert A. , Park Ryan S. 
Published: January 2025

Abstract
R. A. Jacobson determined the orbits of the Uranian satellites, the masses of Uranus and its satellites, and the orientation of the pole of Uranus from Earth-based astrometry, Earth-based ring occultations, and observations acquired with the Voyager 2 spacecraft. Subsequent to that publication, several observers obtained new astrometry, and some of the original astrometry was rereduced against the Gaia star catalog. Moreover, R. G. French et al. made a new determination of the orbits of the Uranian rings, the orientation of the Uranian pole, and the gravity harmonics of Uranus from the entire set of Uranian ring occultations. Here we report the results of an analysis that redetermined the Uranus and satellite masses, satellite orbits, and the orbit of Uranus. In addition, we obtained a value for the Uranus tidal dissipation factor and produced an independent determination of the Uranian ring orbits, Uranus pole direction, and Uranus gravity harmonics. We also developed new expressions for the orientations of the satellites. We processed all of the data from our previous work plus the new and rereduced astrometry and the ring occultations. We extended our data arc forward to 2016 and backward to 1847. Our new orbit for Uranus is an update of that in ephemeris DE440 incorporating the occultation data and Gaia astrometry.
Back-illuminated Light-spot-mapping Algorithm for Dual Rotation Robotic Fiber Positioners Based on an Artificial Probability Potential Field Method
Authors: Wang Yingfu , Zhou Jiahao , Liu Ziming , Chen Rongfeng , Xie Jiacheng , Hu Hongzhuan , Wang Jianping , Liu Zhigang , Chu Jiaru , Zhang Feifan , Zhang Haotong , Zhang Yong , Zhou Zengxiang 
Published: January 2025

Abstract
Back-illuminated spot mapping is essential for observations with modern spectroscopic survey telescopes. In the fiber position detection system, after the fiber view camera (FVC) detects the positions of the light spots from the robotic fiber positioners (RFPs), these positions must be mapped to the RFPs individually to complete subsequent calculations of their operational data. The back-illuminated images captured by the FVC show thousands of small light spots, each only hundreds of microns in size, randomly distributed on a completely black background, making accurate one-to-one mapping to the actual RFP positions highly challenging due to the lack of additional RFP features. This study constructs an artificial probability potential field to calculate the likelihood of each light spot appearing in the patrol area of an RFP, employing a global probability potential energy optimization method to establish the optimal mapping relationship. The proposed method successfully maps all light spots in the closed-loop fiber positioning task and is ultimately applied to the fiber positioning system of the Large Sky Area Multi-Object Fiber Spectroscopic Telescope, achieving accurate mapping of 4000 RFPs on the focal plane. This algorithm effectively addresses challenges such as multitarget interference, uniform background, and RFP failures, providing a reliable approach for mapping the back-illuminated points of tens of thousands of dual-rotation RFPs without requiring special backlight designs in future spectral survey telescopes.
Blowing Out the Candle: How to Quench Galaxies at High Redshift—An Ensemble of Rapid Starbursts, AGN Feedback, and Environment
Authors: Kimmig Lucas C. , Remus Rhea-Silvia , Seidel Benjamin , Valenzuela Lucas M. , Dolag Klaus , Burkert Andreas 
Published: January 2025

Abstract
Recent observations with JWST and the Atacama Large Millimeter/submillimeter Array have revealed extremely massive quiescent galaxies at redshifts of z = 3 and higher, indicating both rapid onset and quenching of star formation. Using the cosmological simulation suite Magneticum Pathfinder, we reproduce the observed number densities and stellar masses, with 36 quenched galaxies of stellar mass larger than 3 × 1010
M
⊙ at z = 3.42. We find that these galaxies are quenched through a rapid burst of star formation and subsequent active galactic nucleus (AGN) feedback caused by a particularly isotropic collapse of surrounding gas, occurring on timescales of around 200 Myr or shorter. The resulting quenched galaxies host stellar components that are kinematically fast rotating and alpha-enhanced, while exhibiting a steeper metallicity and flatter age gradient compared to galaxies of similar stellar mass. The gas of the galaxies has been metal enriched and ejected. We find that quenched galaxies do not inhabit the densest nodes, but rather sit in local underdensities. We analyze observable metrics to predict future quenching at high redshifts, finding that on shorter timescales <500 Myr, the ratio M
bh/M
* is the best predictor, followed by the burstiness of the preceding star formation, t
50–t
90 (time to go from 50% to 90% stellar mass). On longer timescales, >1 Gyr, the environment becomes the strongest predictor, followed by t
50–t
90, indicating that at high redshifts the consumption of old gas and lack of new gas are more relevant for long-term prevention of star formation than the presence of a massive AGN. We predict that relics of such high-z quenched galaxies should best be characterized by a strong alpha enhancement.
La recherche agronomique en contexte de crise : cas du PITAG en Haïti
Authors: Augustin Pierre Garry 
Published: January 2025

Dans cet article, nous avons analysé le cas d’un ensemble d’activités de recherche agronomique conduites dans le cadre d’un programme de recherche-formation-vulgarisation implémenté en Haïti, en pleine situation de crise multidimensionnelle. L’article donne un premier bilan des conséquences de cette dernière sur les capacités et résultats de recherche. S’appuyant sur les activités du Programme d’Innovation Technologique en Agriculture et Agroforesterie du ministère de l’Agriculture co-financé par la BID/GAFSP/FIDA, il montre que la pandémie de Covid-19, la situation sociopolitique, la crise sécuritaire de 2020 à 2024 ont eu des répercussions importantes sur la recherche, mais que les acteurs du système d’innovation haïtien ont démontré une résilience étonnante et ont apporté des réponses appropriées aux problèmes identifiés. Les résultats ont été assez conséquents : entre autres 8 diagnostics agro-socio-économiques réalisés, 39 paquets techniques adaptés mis au point et prêts à être diffusés auprès des agriculteurs, un renforcement conséquent des capacités des structures de recherche, publications scientifiques sous formes d’articles et de posters, 11 mémoires de Master et 5 thèses de doctorat, un laboratoire de culture in vitro installé ainsi que 9 stations agro climatiques, des répertoires des produits et des paquets techniques élaborés ainsi qu’un document de capitalisation de l’expérience (appelé programme de Recherche-Formation-Vulgarisation) destiné aux universités…). Mais on ne peut ignorer les limites (un recul insuffisant, un manque d’exhaustivité…) qui invitent à entreprendre d’autres études en vue de mettre en évidence les possibilités qui se sont présentées pendant et après les crises en vue de réorienter le système d’innovation national, tirer les leçons des différentes expériences de façon à rendre le système plus résilient et plus durable encore, élaborer/adopter des politiques visant à renforcer sa capacité de réaction en cas de nouvelles crises (ou de leur approfondissement) et évaluer la pertinence de les adapter à d’autres contextes.