bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vitamin E Treatment Improves the Antioxidant Capacity of Patients Receiving Dialysis: A Systematic Review and Meta‐Analysis
Authors: Ni Ce , Zhou Wenhua , Yu Mengyuan , Li Xinyang , Li Jian , Cui Yingchun , Cui Wenpeng 
Published: September 2023

ScopeTo summarize the effect of vitamin E‐coated dialyzer membranes (VEMs) treatment or oral vitamin E intake on antioxidant molecules, such as superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), and total antioxidant level in patients receiving dialysis.Methods and resultsA literature search of PubMed, Embase, CNKI, and the Cochrane Library databases is performed from inception to July 1, 2023, with no language nor country restrictions. Twenty‐four experimental studies involving 512 patients undergoing dialysis are selected for meta‐analysis. The levels of antioxidant markers in the blood of patients receiving hemodialysis (HD) improve with long‐term VEMs treatment (p = 0.016). According to the findings of each antioxidant index, there is a significant increase in the levels of erythrocyte‐derived SOD (p = 0.047), CAT (p = 0.029), and plasma‐derived total antioxidant level (p < 0.001). The antioxidant marker levels in patients receiving HD are significantly increased by oral vitamin E intake (p < 0.001). Erythrocyte‐derived SOD (p = 0.003), GPX (p < 0.001), and CAT (p = 0.001) substantially improves after 2–6 months of intervention with oral vitamin E preparation. The antioxidant index of patients receiving peritoneal dialysis (PD) is unaffected by oral vitamin E treatment (p = 0.945).ConclusionVitamin E therapy has a favorable effect on the retention of antioxidant compounds in patients undergoing dialysis.
Compact wideband MIMO antenna with fragmented patches for 5G mobile terminals
Authors: Liu An , Liu Juhua 
Published: September 2023

AbstractA compact wideband MIMO antenna obtained by breaking up an intact rectangular patch into a 2 × 5 small patch array with connected strips is proposed for 5G mobile terminals. The diagonal small patches are connected with the metal strips respectively, so as to constitute an interleaved double branch composed of a main branch and a parasitic branch, thus achieving compactness. The main branch fed by two ports operates at 4.5 GHz, and the parasitic branch coupled by the main branch achieves a lower resonant frequency of 3.35 GHz, thus widening the bandwidth. The small patches in the middle are connected to the ground to improve the isolation. A short length of 21.5 mm (about 0.24 wavelength of the lower‐edge frequency) of the proposed antenna pair is realized. Besides, an eight‐element MIMO antenna is designed and fabricated. Measured results show the reflection coefficients are lower than −6 dB, and the transmission coefficients between every two ports are lower than −10 dB in the 5G N77/N78/N79 bands (3.3–5.0 GHz). The average total efficiencies are 70.4% and 63.8% for antenna 1 and antenna 2, respectively. The ECCs are lower than 0.15.
Analysis of two fully discrete spectral volume schemes for hyperbolic equations
Authors: Wei Ping , Zou Qingsong 
Published: September 2023

AbstractIn this paper, we analyze two classes of fully discrete spectral volume schemes (SV) for solving the one‐dimensional scalar hyperbolic equation. These two schemes are constructed by using the forward Euler (EU) method or the second‐order Runge–Kutta (RK2) method in time‐discretization, and by letting a piecewise kth degree( is an arbitrary integer) polynomial satisfy the local conservation law in each control volume designed by subdividing the underlying mesh with Gauss–Legendre points (LSV) or right‐Radau points (RRSV). We prove that for the EU‐SV schemes, the weak(2) stability holds and the norm errors converge with optimal orders , provided that the CFL condition is satisfied. While for the RK2‐SV schemes, the weak(4) stability holds and the norm errors converge with optimal orders , provided that the CFL condition is satisfied. Here and are, respectively, the spacial and temporal mesh sizes and the constant is independent of and . Our theoretical findings have been justified by several numerical experiments.
Are 24‐hour movement recommendations associated with obesity‐related indicators in the young population? A meta‐analysis
Authors: López‐Gil José Francisco , Tapia‐Serrano Miguel Angel , Sevil‐Serrano Javier , Sánchez‐Miguel Pedro Antonio , García‐Hermoso Antonio 
Published: September 2023

AbstractObjectiveThis study aimed to determine the relationship between meeting all three 24‐hour movement recommendations (i.e., physical activity, sleep duration, and screen time) and obesity‐related indicators among young people.MethodsFour databases were systematically searched (PubMed, Scopus, Web of Science, and Cochrane Library).ResultsMeeting the 24‐hour movement recommendations was cross‐sectionally associated with lower overall obesity‐related indicators (r = −0.09, 95% CI: −0.11 to −0.06), but no longitudinal association was found. Regarding each obesity‐related indicator separately, meeting all three recommendations was related to lower odds of overweight/obesity (odds ratio = 0.65, 95% CI: 0.56 to 0.76) and obesity alone (odds ratio = 0.28, 95% CI: 0.16 to 0.50). An inverse relationship between meeting 24‐hour movement recommendations and BMI, BMI z score, waist circumference, and body fat was also found. Regarding subgroup analysis, the association between 24‐hour movement recommendations and overall obesity‐related indicators was similar regardless of sex, comparison used (meeting all three vs. not meeting [i.e., those who met zero to two of the movement behaviors] or meeting all three vs. none), and type of measure to assess 24‐hour movement recommendations (i.e., self‐reported or accelerometer‐based measures).ConclusionsMeeting all 24‐hour movement recommendations may be a crucial factor in maintaining a healthy weight status in the young population.
Use of CFTR modulators in special populations, part 2: Severe lung disease
Authors: Elijah Joseph , Fitzgerald Linda J. , Phan Hanna 
Published: September 2023

AbstractSafety and efficacy data surrounding cystic fibrosis transmembrane regulator (CFTR) modulator administration for people with CF (pwCF) and severe lung disease elect has remained unclear as a result of exclusion from key trials. A scoping review of English language articles from the period of 1 January 2012, to 31 July 2023 was conducted utilizing PubMed and EmBase databases with the following terms: “severe lung disease” OR “advanced lung disease” AND “ivacaftor OR lumacaftor OR tezacaftor OR elexacaftor”; “cystic fibrosis transmembrane conductance regulator” AND “off label drug use.” Search results were reviewed by title and abstract for relevance. Twenty articles specific to CFTR modulator use in the setting of severe lung disease were included for review, with few specific to pediatric‐aged pwCF. PwCF and severe lung disease experienced significant improvement in pulmonary function, body weight, number of IV antibiotic days, and quality of life. A few studies reported a transient decline in pulmonary function among pwCF shortly after LUM/IVA initiation. However, preemptive reductions in the dose of LUM/IVA may mitigate this reaction. ELE/TEZ/IVA utilization in pwCF and severe lung disease appears to be devoid of the transient decline in pulmonary function observed with LUM/IVA while providing the same clinical benefit. Current available data regarding use of CFTR modulators in pwCF and severe lung disease is reassuring; however, there remains a lack data regarding outcomes among the pediatric population including long‐term outcomes. Therefore, treatment decisions should be individualized and coproduced.
Raincloud conditioning by thunder
Authors: Temkin Samuel 
Published: September 2023

AbstractThis article considers the role of thunder in the production of rain by gravitational processes. A previous numerical work has shown that a thunder event consisting of four consecutive thunderclaps can alone produce small but significant droplet growths in a lean cumulus cloud in less than 2 s. Here we consider, also numerically, the coalescence effects produced by both thunderclaps and gravity in a cumulus congestus cloud that had more than four times the liquid content of that lean cloud. Those effects are studied separately and in tandem, using the same set of assumptions. Therefore, the results presented here provide a basis for the comparison of the effectiveness of each type to produce droplet growth in thunderclouds. For thunder alone, these results show that a small number of thunderclaps can in less than 2 s produce mean size growths larger than 50%. For gravity alone, it is found that after 60 s, the longest time considered, gravitational coalescence increases the mean diameter of the original droplet size distribution by 20%. The tandem study considers the effects produced by gravitation on the droplet size distribution that resulted after the original distribution was modified by four or five thunderclaps. Significant increases are found in both cases. For four claps it was found that the mean size increased by 71% in 60 s. The corresponding growth for five claps was slightly larger than 100%. These substantial increases also show that the growths produced by the thunderclaps are not simply additive, but significantly accelerate those produced by gravitation. This acceleration implies that the droplet size growths produced by thunderclaps can substantially decrease the time required by gravitational coagulation to produce raindrops in rainclouds.
Successful Long-Term Guselkumab Treatment of Severe Plaque Psoriasis in Patients with Class III Obesity: A Case Series
Authors: Galluzzo Marco , Marcelli Lorenzo , Fico Angela , Bianchi Luca , Talamonti Marina 
Published: September 2023

Abstract
Data from real-world studies and clinical trials have documented the long-term efficacy and safety of guselkumab in patients with moderate-to-severe psoriasis. Limited data are available on the long-term use of guselkumab in morbidly obese individuals with severe psoriasis. Here, we present data on the outcome of three patients with class III obesity (body mass index (BMI) of ≥40 kg/m2) with severe plaque psoriasis treated with 100 mg guselkumab. At baseline, mean BMI was 46.5 ± 5.4 kg/m2 and mean PASI was 46.0 ± 18.5 and all patients were biologic naïve. After 12 weeks of guselkumab treatment, mean PASI decreased to 9.7 ± 4 and to 4.0 ± 1.7 at 28 weeks. After 1 year, two patients achieved complete remission and one patient had PASI of 6 (achieving remission by week 140). All three patients are still in complete remission. Our real-life results in specific patients burdened with class III obesity naïve to biologic treatment show excellent long-term psoriasis outcome with guselkumab.
Bug report priority prediction using social and technical features
Authors: Huang Zijie , Shao Zhiqing , Fan Guisheng , Yu Huiqun , Yang Kang , Zhou Ziyi 
Published: September 2023

SummarySoftware stakeholders report bugs in issue tracking system (ITS) with manually labeled priorities. However, the lack of knowledge and standard for prioritization may cause stakeholders to mislabel the priorities. In response, priority predictors are actively developed to support them. Prior studies trained machine learners based on textual similarity, categorical, and numeric technical features of bug reports. Most models were validated by time‐insensitive approaches, and they were producing suboptimal results for practical usage. While they ignored the social aspects of ITS, the technical aspects were also limited in surface features of bug reports. To better model the bug report, we extract their topic and most similar code structures. Since ITS bridges users and developers as the main contributors, we also integrate their experience, sentiment, and socio‐technical features to construct a new dataset. Then, we perform two‐classed and multiclassed bug priority prediction based on the dataset. We also introduce adversarial training using generated training data with random word swap and random word deletion. We validate our model in within‐project, cross‐project, and time‐wise scenarios, and it outperforms the two baselines by up to 15% in area under curve‐receiver operating characteristics (AUC‐ROC) and 19% in Matthews correlation coefficient (MCC). We reveal involving contributor (i.e., assignee and reporter) features such as sentiment that could boost prediction performance. Finally, we test statistically the mean and distribution of the features that reflect the differences in social and technical aspects (e.g., quality of communication and resource distribution) between high and low priority reports. In conclusion, we suggest that researchers should consider both social and technical aspects of ITS in bug report priority prediction and introduce adversarial training to boost model performance.
Large‐Area Inkjet‐Printed Flexible Hybrid Electrodes with Photonic Sintered Silver Grids/High Conductive Polymer
Authors: Kant Chandra , Mahmood Sadiq , Seetharaman Madhu , Katiyar Monica 
Published: September 2023

AbstractThe field of printed organic electronics has not only made flexible devices accessible but also allows the production process toward a high throughput industrial scale. The current research involves the inkjet‐printing of an indium tin oxide‐free large‐area flexible hybrid electrode compose of a high conductivity organic layer (PEDOT: PSS) as a main electrode and inorganic silver nanoparticles‐based grid/film for the auxiliary electrode. The current bottleneck in the roll‐to‐roll production of printed electronics is the time required for the conductive inks to dry and sinter. Flash sintering is used to dry nano‐silver conductive ink to 77.6 m Ω □−1 sheet resistance in <20 ms, the quickest annealing procedure, without damaging flexible substrates. Flexible organic light‐emitting diodes (OLEDs) are created with a large active area (500 mm2) to demonstrate the efficacy of the flexible hybrid electrodes and the excellent bending stability (4 mm bending radius) of OLEDs. Maximum current efficiency of 19.58 cd A−1 and a maximum luminescence of 8708 cd m−2 at a low turn‐on voltage of 3.1 V for the small‐area (16 mm2) OLEDs are achieved. This method is promising for reducing indium consumption and paving the way for creating new high throughout hybrid electrodes for large‐area flexible printed electronics.
Development of stability indicating liquid chromatographic method for estimation of novel anti‐diabetic drug Evogliptin
Authors: Gajjar Deepanti , Shah Dimalkumar S. 
Published: September 2023

AbstractEvogliptin (EVG) is prescribed in the treatment of type 2 diabetes. An accurate and precise high‐performance liquid chromatographic method along with forced degradation studies and design of experiments has been developed for the estimation of EVG. Agilent C18 Column (250 × 4.6 mm, 5 μm particle size) was used as the stationary phase and methanol: 0.05% Orthophosphoric acid in water (51: 49% V/V) was used as the mobile phase. The method was linear in the concentration range of 5–30 μg/ml with a correlation coefficient (r2) of 0.9996. The proposed method was validated with respect to linearity, accuracy, precision, and robustness as per the International Conference on Harmonization Q2 (R1) guideline. A forced degradation study was performed to find out the intrinsic stability of the molecules. The degradation products were well resolved from the drug peak and did not interfere with the analysis. The method was successfully applied for the analysis of EVG.
Evaluation of breeding objectives, breeding practices and reproductive performance of indigenous dairy cows in selected districts of Kaffa Zone, South West Ethiopia
Authors: Asfaw Yakob , Begna Regasa , Masho Worku 
Published: September 2023

AbstractBackgroundBreeding objectives are designed to achieve targeted dairy cow production goals, which can be affected by production type, farmer preferences, environmental factors and genetic factors individually or in combination. Breeding practices, such as both controlled and uncontrolled, and artificial insemination (AI) are the tools used to obtain the desired breeding objectives. The lower reproductive performance of indigenous dairy cows affects the total milk production and calf crops that are produced during their lifetime. Designing appropriate breeding objectives and breeding practices can improve the reproductive performance of dairy cows and their overall production performance.Materials and methodsThe current study was conducted with the objective of evaluating the breeding, practices and performance of indigenous dairy cattle in the south western part of Ethiopia. The districts of Gesha and Chena were purposefully chosen. The study design for the 384 household surveys was a cross‐sectional survey with a simple random sample approach. Data analysis was carried out by MS‐Excel (2010) and the general linear model procedure of SAS of 2008.ResultsThe current study revealed that methods of breeding were predominantly natural‐controlled mating, followed by natural‐uncontrolled mating and AI in descending order. Breeding objectives were input function, output function, sociocultural and economic functions and assets and security functions in decreasing order of rank. Reproduction performance indexes of indigenous dairy cows age at first service (3.72 ± 0.05 years), age at first calving (AFC) (4.71 ± 0.07 years), calving interval (CI) (1.58 ± 0.03 years), days open (DO) (4.26 ± 0.11 months), services per conception in natural mating (1.4 ± 0.08) and AI (2.73 ± 0.14), age of bull at maturity (4.17 ± 0.74 years), interoestrus interval (23.18 ± 0.61 days), calves crop (7.53 ± 0.22) and the life span of indigenous dairy cow (11.94 ± 0.26 years) were significant (p < 0.01) between two districts, whereas the values of age of bull at maturity and number of services per conception in natural mating were significant (p < 0.05) between districts.ConclusionsUsing AI and major reproduction performances, such as AFC, CI and DO of indigenous dairy cows in the study area, were very low. Therefore, concerned bodies should intervene to improve reproduction performance through the utilization of AI techniques, with the integration of forage development activities and improvements in livestock health care.
Two cases of acquired porto‐systemic shunt in association with veno‐occlusive disease in captive Northern cheetah (Acinonyx jubatus soemmeringii) with insights into antemortem diagnostics
Authors: Torres‐Blas Irene , Tubb Francesca , Molenaar Fieke , Spiro Simon 
Published: September 2023

AbstractTwo Northern cheetahs (Acinonyx jubatus soemmeringii) were euthanased at the Zoological Society of London's Whipsnade Zoo due to old age and degenerative joint disease. Both animals were found to have mild to moderate fibrosis of the space of Disse (veno‐occlusive disease) and multiple congested, tortuous vessels running from the hepatic portal vein to the caudal vena cava (acquired portosystemic shunt). We hypothesise that the shunts result from portal hypertension caused by the veno‐occlusive disease, and that this helps relieve pressure on the sinusoidal endothelium, limiting progression of the disease. As acquired portosystemic shunt is a known sequel to portal hypertension, we believe that acquired portosystemic shunt may be more common in cheetahs with veno‐occlusive disease than is currently reported, and provide a practical protocol and gross images as diagnostic tools to aid in the postmortem diagnosis of this condition.
Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat
Authors: Colella Antonella , Greco Grazia , Cordisco Marco , Tinelli Antonella , Paradies Paola 
Published: September 2023

AbstractFeline infective endocarditis is a difficult condition to detect and diagnose early, with a poor long‐term prognosis. This case report describes the clinical, laboratory, instrumental and histological findings in a 12‐year‐old cat with Bartonella henselae endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia. The latter pathogen recently emerged as deadly nosocomial bacteria in humans and is considered a common cause of infective endocarditis. The prolonged corticosteroid therapy administered in the cat probably played a role in the onset of B. henselae endocarditis and E. faecalis intestinal translocation and bacteraemia. Echocardiography remains the tool of choice to suspect infective endocarditis, as it can detect vegetative lesions consistent with this condition. Feline infective endocarditis should always be considered as a differential diagnosis in cats, especially when there are signs of systemic disease, a history of prolonged corticosteroid treatment or concomitant infections.
Immune‐mediated haemolytic anaemia with severe thrombocytopenia in a Pembroke Welsh Corgi
Authors: Tucker Samuel M. , Baja Alexie J. , Rasche Brittany L. , Negrão Watanabe Tatiane Terumi , Harrell Karyn A. 
Published: September 2023

AbstractAn 8‐year‐old, female, spayed Pembroke Welsh Corgi presented for a 3‐day history of worsening lethargy and pale pink mucous membranes. Hematological analysis revealed a normocytic, normochromic, regenerative anaemia, positive saline agglutination and marked thrombocytopenia, supportive of a diagnosis of immune‐mediated haemolytic anaemia and thrombocytopenia, either as a secondary result of immune‐mediated haemolytic anaemia or an additional immune‐mediated process. Due to continued decreases in packed cell volume despite immunosuppressive therapy and packed red blood cell transfusion, euthanasia was elected. Gross postmortem examination revealed cutaneous and visceral petechiae to ecchymoses, visceral icterus, and moderate splenomegaly. Microscopically, the bone marrow was hypercellular with moderate to marked increase in numbers of erythroid lineage cells relative to myeloid lineage cells. Few macrophages displayed erythrophagia. Given the drastically worsening thrombocytopenia, immune‐mediated thrombocytopenia was considered more likely, but this could not be entirely verified. This presentation of immune‐mediated haemolytic anaemia with thrombocytopenia illustrates the clinical diagnosis and management of immune‐mediated haematological diseases in dogs.
Using banding data to estimate primary feather molt and hatch chronology of white‐winged doves in Texas
Authors: Hall Jared D. , Mathewson Heather A. , Oldenburger Shaun L. , Frisbie Mike , Schwertner Thomas W. 
Published: September 2023

AbstractBanding data are commonly used to estimate vital rates for migratory game bird management. We used white‐winged dove (Zenaida asiatica) banding data to estimate molt and hatch chronology in Texas. We used Texas Parks and Wildlife Department's long‐term, state‐wide banding data (71,675 banded individuals) from 1 June to 15 August 2007–2016 to investigate primary feather molt and hatching in white‐winged doves in Texas. We estimated primary feather molt and used individual recapture data to determine reliability of models predicting primary feather molt rates. For hatching, we used primary feather molt scores of captured hatch‐year doves to backdate to an estimated hatch date. Our modeling predicted mean after‐hatch‐year primary feather molt rate of 13.21 ± 0.93 days. We predicted 95% of adult white‐winged doves began molting between 7 April to 8 July and completed molt between 17 August to 17 November. Across all years, white‐winged doves hatched as early as 6 January and as late as 27 July, with 95% of all hatching occurring between 22 March and 18 June and peaking on 4 May. Primary feather molt initiation peaked 16 days after the peak of hatching, suggesting that white‐winged doves delay the onset of primary molt until reproductive activity slows. Secondary data collected during banding operations on migratory game birds may be used to understand additional life processes without the requirement to initiate additional survey efforts.