bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing a telehealth medical nutrition therapy (MNT) service for adults living in rural Australia at risk of cardiovascular disease: An intervention development study
Authors: Herbert Jaimee , Schumacher Tracy , Brown Leanne J. , Collins Clare E. 
Published: June 2023

AbstractBackgroundReceiving medical nutrition therapy (MNT) from an accredited practising dietitian (APD) can reduce diet‐related cardiovascular disease (CVD) risk factors. However, people living in rural areas of Australia experience barriers to accessing dietitians because of their remote location. Telehealth has the potential to improve dietetic access in rural areas; however, there is limited research into the development and delivery of telehealth MNT interventions specific to these areas. The present study describes the development of the Healthy Rural Hearts (HealthyRHearts) telehealth MNT intervention, which was developed as a part of the HealthyRHearts randomised control trial, set in primary care practices in rural areas of the Hunter New England and Central Coast Primary Health Network. The aim of HealthyRHearts is to improve diet‐related risk factors for CVD in rural adults at moderate to high CVD risk using a telehealth MNT intervention delivered by an APD.MethodsThe study describes the development of the HealthyRHearts telehealth MNT intervention, using the 14‐item GUIDance for rEporting of intervention Development (GUIDED) checklist and the Template for Intervention Description and Replication (TIDieR) framework to guide description.ResultsHealthyRHearts is a complex intervention that aims to translate a telehealth MNT intervention for CVD prevention into rural and remote primary care settings. The intervention is designed to be implemented across multiple sites of varying characteristics and needs, with the ability to accommodate individual complexities within the rural context and target population. Participants are adults aged 45–75 years who are assessed as moderate to high risk of CVD by their general practitioner (GP). Consenting participants are referred to the intervention by their GPs and receive five telehealth MNT consultations with an APD over 6‐months. APDs are trained in the intervention protocol including intervention materials, resources and behaviour change counselling strategies.ConclusionUsing the GUIDED and TIDieR frameworks to guide description of the HealthyRHearts intervention development process facilitates detailed description of decision‐making pathways for each element of the intervention design. The comprehensive description of the intervention development process for HealthyRHearts is intended to facilitate replication, iteration and optimisation of the intervention for rural contexts.
Continuous glucose monitoring with data sharing in older adults: A qualitative study
Authors: Allen Nancy A. , Grigorian Ernest G. , Mansfield Kelly , Berg Cynthia A. , Litchman Michelle L. 
Published: June 2023

AbstractAimsThis study examined the perceptions of the SHARE plus intervention and its effects on communication, collaboration, and involvement in day‐to‐day diabetes management in older adults with Type 1 diabetes (T1D) and their care partners.BackgroundThe SHARE plus intervention includes continuous glucose monitoring with a data sharing app that allows care partners to view glucose data on a smartphone and receive alerts. People with T1D and their care partners are educated about communication strategies, problem‐solving strategies, and action planning when using glucose data sharing.DesignQualitative descriptive design.MethodsOlder adults with T1D wore a continuous glucose monitor for 3 months (n = 10). Care partners (n = 10) used a data‐sharing app. The SHARE plus intervention consisted of one 90‐min education session. Semi‐structured interviews were conducted across 10 dyads (person with diabetes and care partner) following the 12‐week study. A qualitative description and a constant comparison approach were used to examine similarities and differences in experiences. Interviews were transcribed, coded, and analysed for common themes. The manuscript adheres to COREQ EQUATOR checklist.ResultsThe SHARE plus intervention increased diabetes knowledge across the dyads, improving confidence and helping partners understand how to navigate symptoms and behaviours and when to intervene. Dyads worked together to optimise diabetes management through improved communication, collaboration, and management of disagreements. Although the majority of persons with diabetes and their care partners reported no conflictual communication, disagreements about diabetes management remained in some dyads. The SHARE plus intervention impacted care partners in various ways from a psychological perspective. While live‐in‐care partners felt peace of mind, care partners living away from persons with diabetes had some increased worry and concern.ConclusionThe SHARE plus intervention results can help guide future development of diabetes dyadic care and education interventions using diabetes technology.Relevance to Clinical PracticeThe SHARE plus intervention is a brief, practical intervention that can help diabetes clinicians improve communication and collaboration among spouses living with older adults with T1D who use continuous glucose monitoring with data sharing.Patient ContributionA person with diabetes was part of the research team and assisted with design of the intervention and subsequent interviews and analysis.
Telemedicine in the diagnosis and management of temporomandibular disorders: A systematic review conducted according to PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions
Authors: Abdul Nishath Sayed , Kumari Minti , Shenoy Mahesh , Shivakumar Ganiga Channaiah , Herford Alan Scott , Cicciù Marco , Minervini Giuseppe 
Published: June 2023

AbstractBackgroundTelemedicine (T‐Med) has always been an important tool in the arsenal of clinicians worldwide. This technique has become increasingly popular in recent years, especially in light of the COVID‐19 pandemic, which has made it difficult for some people to access traditional dental care. The current review aimed to analyse the usage of telemedicine in the diagnosis and management of temporomandibular disorders (TMDs) and its impact on general health.MethodsAn extensive search of databases was conducted using keywords such as, “telemedicine,” “teledentistry,” “TMJ” and “temporomandibular disorders,” resulting in a total of 482 papers to be available from which eligible studies were selected. The Risk of Bias in Observational Studies of Exposures (ROBINS‐E) tool was used to evaluate methodological quality of included studies.ResultsTwo studies were selected which fulfilled the eligibility criteria. All assessed studies indicated varying degrees of positive outcomes for patients who were intervened for TMDs using T‐Med.ConclusionT‐Med shows promising results for the diagnosis and management of TMDs, especially since the advent of the COVID‐19 pandemic and thereafter. Long‐term clinical trials with larger samples are needed to further ascertain validity in this regard.
Multiplexed LC‐MS/MS quantification of salivary RNA modifications in periodontitis
Authors: Vignon Margaux , Bastide Amandine , Attina Aurore , David Alexandre , Bousquet Philippe , Orti Valérie , Vialaret Jérôme , Lehmann Sylvain , Periere Dominique DevilleDe , Hirtz Christophe 
Published: June 2023

AbstractObjectiveTo analyse the salivary epitranscriptomic profiles as periodontitis biomarkers using multiplexed mass spectrometry (MS).BackgroundThe field of epitranscriptomics, which relates to RNA chemical modifications, opens new perspectives in the discovery of diagnostic biomarkers, especially in periodontitis. Recently, the modified ribonucleoside N6‐methyladenosine (m6A) was revealed as a crucial player in the etiopathogenesis of periodontitis. However, no epitranscriptomic biomarker has been identified in saliva to date.Materials and MethodsTwenty‐four saliva samples were collected from periodontitis patients (n = 16) and from control subjects (n = 8). Periodontitis patients were stratified according to stage and grade. Salivary nucleosides were directly extracted and, in parallel, salivary RNA was digested into its constituent nucleosides. Nucleoside samples were then quantified by multiplexed MS.ResultsTwenty‐seven free nucleosides were detected and an overlapping set of 12 nucleotides were detected in digested RNA. Among the free nucleosides, cytidine and three other modified nucleosides (inosine, queuosine and m6Am) were significantly altered in periodontitis patients. In digested RNA, only uridine was significantly higher in periodontitis patients. Importantly there was no correlation between free salivary nucleoside levels and the levels of those same nucleotides in digested salivary RNA, except for cytidine, m5C and uridine. This statement implies that the two detection methods are complementary.ConclusionThe high specificity and sensitivity of MS allowed the detection and quantification of multiple nucleosides from RNA and free nucleosides in saliva. Some ribonucleosides appear to be promising biomarkers of periodontitis. Our analytic pipeline opens new perspectives for diagnostic periodontitis biomarkers.
Extrudability of cookie batters evaluated with three measurement methods
Authors: De Souter Rachel , Vandeweyer Dries , Claes Johan 
Published: June 2023

AbstractFor cookie batters, there is a strong interaction between ingredient formulation and processing. Changing the amounts and types of sugar and fat in a recipe to change taste or healthiness influences the type of product formation in a production plant. In this study, the applicability of three measurement methods, a rheometer, a forward extrusion cell, and the Foodtexture Puff Device (FPD), was evaluated to measure the extrudability of cookie batters. When looking at the sugar and fat content, both the rheometer and the FPD proved to be consistent and reliable methods to describe the impact of those ingredients on extrudability. A further optimization of the measurement settings of the FPD may improve the performance of this new method. Although the forward extrusion cell performed well for recipes with an increasing sugar content, it did not yield proper results for recipes with a higher fat content due to a separating fat layer. This also limited the applicability of the forward extrusion cell for different fat types, while the other two methods performed well in that case. The small differences in consistency due to different sugar grain sizes were properly described by the forward extrusion cell and the FPD. Overall, it can be concluded that the rheometer performed best to analyze the extrudability of cookie batters, closely followed by the FPD, of which the measurement settings can be optimized. These methods can also be used in the product development phase.
Satellite image survey of beluga whales in the southern Kara Sea
Authors: Fretwell Peter T. , Cubaynes Hannah C. , Shpak Olga V. 
Published: June 2023

AbstractThe use of satellite imagery to find, count and monitor whales in remote and hard to access areas has shown some promise, but few satellite studies have, as yet, provided substantial conservation outcomes. Recent studies have shown the ability of very high‐resolution satellites to detect and count previously surveyed populations of belugas and narwhals in Canada. Here we describe the detection of a large aggregation of a poorly surveyed population of belugas in the southern Kara Sea, Russia, in a region where Soviet whaling is known to have had a heavy toll on belugas. We counted over 1,100 surface belugas using very high‐resolution satellite imagery. As only an unknown portion of the belugas can be seen on the surface, accurately converting the surface count to an abundance estimate will need further study, but using the analog of aerial surveys we estimate that this aggregation is between ~1,150–2,870 individuals. Although the species is not currently considered endangered, concern over belugas future population trends is increasing, as the species is reliant on Arctic sea ice, which is rapidly declining due to climate change. This study shows the utility of satellite imagery to discover and monitor new and little‐known cetacean populations.
An evidence‐based protocol for sensory soothing in paediatric intensive care
Authors: Boles Jessika , Wilson Sarah , Woodburn Ashlie , Betters Kristina 
Published: June 2023

AbstractIn recent years, an increasing body of literature has highlighted the significant sequelae of a paediatric intensive care unit admission for children and their families. More innovative bedside approaches are needed to support children's coping and development and help minimize the use of sedatives, given their known deleterious effects. To support nursing staff in managing agitation in critically ill infants and children, a ‘Sensory Pyramid’ program was built in collaboration with occupational therapists, child life specialists and critical care nursing staff at an academic medical center in the United States. Anchored in evidence‐based and developmentally appropriate non‐pharmacologic sensory soothing techniques, the protocol outlines escalating comfort interventions nurses can employ that are safe and feasible for implementation by bedside staff and families.
Predictors of pacing‐induced cardiomyopathy detection and outcomes demonstration after conduction system pacing upgrade on patients with long‐term persistent atrial fibrillation
Authors: Wang Nan , Ma Pei‐pei , Jing Zhao‐meng , Chen Ying , Jia Jing‐jing , Zhao Fu‐lu , Zhao Yan‐ni , Xiao Xian‐jie , Li Guo‐cao , Yang Yi‐heng , Ma Cheng‐ming , Gao Lian‐jun , Xia Yun‐long , Yang Yan‐zong , Dong Ying‐xue 
Published: June 2023

AbstractObjectiveTo identify the predictors of pacing‐induced cardiomyopathy (PICM) and illustrate the safety and feasibility of conduction system pacing (CSP) upgrade on patients with long‐term persistent atrial fibrillation (AF).MethodsAll patients with long‐term persistent AF and normal left ventricular ejection fraction (LVEF) ≥50% were consecutively enrolled from January 2008 to December 2017, and all the patients with atrioventricular block (AVB) and high right ventricular pacing (RVP) percentage of at least 40%. The predictors of PICM were identified, and patients with PICM were followed up for at least 1 year regardless of CSP upgrade. Cardiac performances and lead outcomes were investigated in all patients before and after CSP upgrade.ResultsThe present study included 139 patients, out of which 37 (26.62%) developed PICM, resulting in a significant decrease in the left ventricular ejection fraction (LVEF) from 56.11 ± 2.56% to 38.10 ± 5.81% (p< .01). The median duration for the development of PICM was 5.43 years. Lower LVEF (≤52.50%), longer paced QRS duration (≥175 ms), and higher RVP percentage (≥96.80%) were identified as independent predictors of PICM. Furthermore, the morbidity of PICM progressively increased with an increased number of predictors. The paced QRS duration (183.90 ± 22.34 ms vs. 136.57 ± 20.71 ms, p < .01), LVEF (39.35 ± 2.71% vs. 47.50 ± 7.43%, p < .01), and left ventricular end‐diastolic diameter (LVEDD) (55.53 ± 5.67 mm vs. 53.20 ± 5.78 mm, p = .03) improved significantly on patients accepting CSP upgrade. CSP responses and complete reverse remodeling (LVEF ≥50% and LVEDD < 50 mm) were detected in 80.95% (17/21) and 42.9% (9/21) of patients. The pacing threshold (1.52 ± 0.78 V/0.4 ms vs. 1.27 ± 0.59 V/0.4 ms, p = .16) was stable after follow‐up.ConclusionPICM is very common in patients with long‐term persistent AF, and CSP upgrade was favorable for better cardiac performance in this patient population.
Spawning induction for Latin American fishes
Authors: Mechaly Alejandro S. , Batlouni Sergio R. , Elisio Mariano , Sanches Eduardo A. , Guzmán Jonathan Chacon , García Minerva Maldonado , Rodríguez‐Forero Adriana , Vissio Paula , Fatsini Elvira , Núñez Jesús , Duncan Neil 
Published: June 2023

AbstractAquaculture offers solutions to meet the growing global demand for fish, and reports from the UN‐FAO indicate that aquaculture production in Latin America (LA) has grown at rates above the world average in recent years. One of the major constraints in the diversification of LA aquaculture is the control of reproduction in several popular native fish species for which difficulties in captive propagation have not yet been sufficiently overcome. This article reviews the use of hormone treatments to promote reproduction in females of these native fish species. LA has played a key role in the history of development of hormone administration, including the first hormonally induced spawning. That contribution is included in a historical overview of the discovery of the major hormones used in fish culture. The review provides a summary of difficulties to propagate females of various native fishes and the effects of administering hormones to enhance reproduction. Induced spawning of certain freshwater species was mainly achieved with pituitary extracts or human chorionic gonadotropin (hCG), although gonadotropin‐releasing hormone analogues (GnRHa) treatments are being researched, and successful studies suggest that low doses may be more effective. Research on new and emerging aquaculture species has applied both gonadotropins (Gths) and GnRHa‐based treatments, and GnRHa treatments have shown potential for marine species. However, native marine species new to aquaculture have also been conditioned to spawn spontaneously without hormones. Finally, we proposed future lines of research to examine reproductive strategies and GnRHa‐based hormone treatments to improve reproductive control for economically important fish species of LA.
Recent advances in acoustic technology for aquaculture: A review
Authors: Li Daoliang , Du Zhuangzhuang , Wang Qi , Wang Jun , Du Ling 
Published: June 2023

AbstractAcoustic technology has great application prospects in aquaculture. In particular, two indispensable, critical technologies for the future aquaculture industry are multi‐sensor acquisition that can achieve multi‐scale information fusion, collection and establishment of a global acoustic fish database and highly developed deep learning intelligent algorithms that can establish a correlation mechanism between fish acoustic and behaviour characteristics. Acoustic technology offers remarkable advantages in large and turbid water bodies for studying spatial and temporal distribution patterns of aquatic organism populations, developing on‐demand feeding systems and estimating biomass. This article reviews the development of acoustic technology and its application in aquaculture over the last 30 years. It further analyses, in detail, the advantages and disadvantages of acoustic technology in evaluating aquatic organism biomass and morphological and physical indicators, aquatic organism behaviour and welfare improvement. Challenges of acoustic technology in acquiring dynamic target data accurately, building a global acoustic fish database and establishing connections between fish behaviour and acoustic characteristics are also discussed. In brief, this article aims to help researchers and practitioners better understand the current state‐of‐the‐art acoustic technologies, which can provide strong support for smart aquaculture applications.
Worst‐case scenarios: Modeling uncontrolled type 2 polio transmission
Authors: Kalkowska Dominika A. , Wiesen Eric , Wassilak Steven G. F. , Burns Cara C. , Pallansch Mark A. , Badizadegan Kamran , Thompson Kimberly M. 
Published: June 2023

AbstractIn May 2016, the Global Polio Eradication Initiative (GPEI) coordinated the cessation of all use of type 2 oral poliovirus vaccine (OPV2), except for emergency outbreak response. Since then, paralytic polio cases caused by type 2 vaccine‐derived polioviruses now exceed 3,000 cases reported by 39 countries. In 2022 (as of April 25, 2023), 20 countries reported detection of cases and nine other countries reported environmental surveillance detection, but no reported cases. Recent development of a genetically modified novel type 2 OPV (nOPV2) may help curb the generation of neurovirulent vaccine‐derived strains; its use since 2021 under Emergency Use Listing is limited to outbreak response activities. Prior modeling studies showed that the expected trajectory for global type 2 viruses does not appear headed toward eradication, even with the best possible properties of nOPV2 assuming current outbreak response performance. Continued persistence of type 2 poliovirus transmission exposes the world to the risks of potentially high‐consequence events such as the importation of virus into high‐transmission areas of India or Bangladesh. Building on prior polio endgame modeling and assuming current national and GPEI outbreak response performance, we show no probability of successfully eradicating type 2 polioviruses in the near term regardless of vaccine choice. We also demonstrate the possible worst‐case scenarios could result in rapid expansion of paralytic cases and preclude the goal of permanently ending all cases of poliomyelitis in the foreseeable future. Avoiding such catastrophic scenarios will depend on the development of strategies that raise population immunity to type 2 polioviruses.
What is an InsurTech? A scientific approach for defining the term
Authors: Sosa Gómez Iván , Montes Pineda Óscar 
Published: June 2023

AbstractThe insurance sector has been transformed as a result of the impact of InsurTech. However, although InsurTech has become a highly relevant concept in recent years, there has yet to be an agreed‐upon meaning of InsurTech. Therefore, it is necessary to establish a solid definition that provides a clear understanding of the term InsurTech. For this purpose, an essential study of the complete scientific production has been carried out through the results obtained for InsurTech in the most relevant databases up to December 31, 2021. This paper aims to define the term InsurTech considering all the contributions made by scholars in the existing academic literature. The research methodology has consisted of an extensive systematic literature review merged with a comprehensive analysis of the nature of the definitions of InsurTech through a three‐stage procedure. A total of 111 academic articles referring to InsurTech have been found. Based on a rigorous analysis and building on the common elements of the 17 meanings provided by the academics, a definition of Insurtech from a scientific approach has been presented. Finally, the nuances of this definition for an Insurtech to be considered as such are discussed and explained.
Household Debt and Risk Tolerance: Evidence From China
Authors: Li Jialong 
Published: June 2023

AbstractThis paper examines the relationship between the head of household's risk tolerance and household debt in China for a sample drawn from the China Household Finance Survey, 2011, 2013, 2015 and 2017. The effect of risk tolerance on both the decision to hold and the amount of total household debt, housing debt and non‐housing debt held is analyzed. The key findings indicate that risk tolerance is positively associated with household debt and non‐housing debt. Differences are found in the effect of risk tolerance on household debt across rural and urban households. For example, there exists a positive relationship between risk tolerance and the probability of holding housing debt for rural households while such a relationship is not found for urban households. In addition, the effect of risk tolerance on household debt is larger for rural households.