bluuebunny/crossref_metadata_2025_split huggingface dataset:
NORMATIZAÇÃO E EXPERIÊNCIA DISCRIMINATÓRIA: ANÁLISE DA CIDADANIA PRECÁRIA LGBTQIA+
Authors: Camacho Soares Mateus , Viana Leão Ingrid 
Published: August 2023

Este artigo analisa as práticas discriminatórias contra a população LGBTQIA+ sob a perspectiva do conceito de necropolítica, bem como na leitura sobre cidadania precária compreendendo que a homo-lesbo-transfobia é parte de um projeto resultante do desprezo e do preconceito social, mas que sempre foi estimulado por forças do Estado. Isto corroborou para que a condição de ser LGBTQIA+ sempre foi objeto de perseguições e violências e que, ao longo da história brasileira. Essas pessoas, com base em orientação sexual e identidade de gênero, não só foram consideradas não detentoras de direitos como tinham as suas existências questionadas. Para este estudo, foi realizado um levantamento sobre compilações jurídicas e dispositivos de leis que regem o Brasil desde o Período Colonial para assim evidenciar que o Estado brasileiro sempre agiu a favor de um país hetero-cisnormativo.
ASSESSMENT CENTER DALAM MANAJEMEN TALENTA ASN
Authors: Puteri Pramudhita 
Published: August 2023

ABSTRAK
Penggunaan metode assessment center dalam pengelolaan ASN sudah menjadi suatu kebutuhan, Akan tetapi, penggunaan assessment center masih menghadapi sejumlah tantangan, khususnya isu validitas metode tersebut yang berdampak pada pemanfaatan hasil uji kompetensi. Kajian literatur ini akan mengeksplorasi ide-ide dari sejumlah penelitian yang dapat digunakan untuk mengembangkan metode assessment center. Tidak hanya itu, kajian literatur ini juga memberikan sejumlah saran yang dapat dilakukan organisasi untuk mengoptimalkan pemanfaatan assessment center dalam manajemen talenta ASN.
Kata Kunci : Assessment Center, Asesor, Desain Simulasi, Validitas

ABSTRACT
The use of the assessment center method in the State Civil Servants management has become a necessity. However, the implementation of assessment center still faces a number of challenges, especially the issue of the validity of the method which has an impact on utilizing the Assessment center’s result. This literature review will explore ideas from a number of studies that can be used to develop the assessment center method. Also, this literature review also provides a number of suggestions that organization could implement to optimize the assessment center utilization in the State Civil Servants Talent Management.
Keywords: Assessment Center, Assessor, Simulation Design, Validity
ANALISIS PERBANDINGAN IMPLEMENTASI LEARNING ORGANIZATION PADA INSTANSI PEMERINTAH
Authors: Purba Asriani , Bawie Puti Paramita 
Published: August 2023

Jurnal ini membahas tentang perbandingan implementasi learning organization pada dua instansi pemerintah yaitu Kementerian Keuangan dan Badan Kepegawaian Negara. Dasar perbandingan ini berdasarkan komponen LO dari Peter Senge dan Cummmings & Worley yaitu personal mastery, mental models, shared vision, team learning, systems thinking, kepemimpinan, struktur organisasi, budaya organisasi, pengembangan SDM, dan sistem informasi. Penulisan ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Penelitian dilakukan berdasarkan hasil observasi, jurnal, buku, data seminar, dan studi peraturan perundang-undangan, serta data lainnya. Hasil penelitian yang penulis dapatkan adalah pada Kemenkeu dan BKN implementasi LO sudah berjalan dan memenuhi semua aspek LO. Namun, pada BKN belum ada peraturan khusus yang mengatur terkait LO sehingga belum adanya komitmen bersama (collective action) untuk mengimplementasikan LO.

Kata kunci: Implementasi. Learning Organization, Institusi Pemerintah
NETRALITAS PEGAWAI NEGERI SIPIL PASCA TERBITNYA PERATURAN PEMERINTAH NOMOR 94 TAHUN 2021 TENTANG DISIPLIN PNS
Authors: SYAEFUDIN ROCHMAT ALI , SUSENO WAHYU HANGGORO , SUBIYANTO NANANG 
Published: August 2023

ABSTRAK. Netralitas Aparatur Sipil Negara (ASN) di Indonesia merupakan problem laten dan kompleks. Pelayanan publik dan demokrasi akan terganggu apabila birokrasi tidak netral. Salah satu penyebab keberpihakan ASN dalam pemilihan umum/pemilihan kepala daerah karena kepentingan karier. Faktor penyebab pelanggaran netralitas ASN diantaranya kurangnya pengawasan dan rendahnya sanksi terhadap pelanggar. Terbitnya Peraturan Pemerintah (PP) Nomor 94 Tahun 2021 tentang Disiplin Pegawai Negeri Sipil (PNS) telah memberikan dukungan dalam penegakan netralitas PNS. PP Nomor 94 Tahun 2021 mengatur lebih rinci larangan bagi PNS terkait netralitas dalam pemilihan umum maupun pemilihan kepala daerah, terutama yang sebelumnya tidak diatur dalam PP Nomor 53 Tahun 2010.
Abstract. The neutrality of the State Civil Apparatus (ASN) in Indonesia is a latent and complex problem. Public service and democracy will be disturbed if the bureaucracy is not neutral. One of the causes of ASN's alignment in the general election/regional head election is due to career interests. The factors that cause violations of ASN neutrality include lack of supervision and low sanctions against violators. The issuance of Government Regulation (PP) Number 94/2021 concerning Discipline of Civil Servants (PNS) has provided support in the enforcement of the neutrality of civil servants. PP Number 94/2021 regulates in more detail the prohibition for civil servants related to neutrality in general elections and regional head elections, especially those that were not previously regulated in Government Regulation Number 53/2010.
PERMASALAHAN PENERAPAN KAMUS KOMPETENSI MANAJERIAL DAN SOSIAL KULTURAL PERMENPAN RB NOMOR 38 TAHUN 2017 DALAM MENILAI KOMPETENSI PEJABAT FUNGSIONAL TERTENTU
Authors: Aman Lusius 
Published: August 2023

ABSTRAK
Ketentuan yang mewajibkan penggunaan kamus kompetensi manajerial dan sosial kultural Permenpan RB Nomor 38 Tahun 2017 dalam penilaian kompetensi terhadap semua ASN pada semua jenis jabatan ternyata menemukan permasalahan tersendiri dalam penerapannya, terutama dalam penilaian bagi jabatan fungsional tertentu. Permasalahan tersebut mencakup akurasi standar kompetensi dan reliabilitas hasil penilaian dan masalah keadilan dalam menilai.
Setelah ditelisik, ternyata deskripsi kompetensi dan indikator perilaku kompetensi manajerial dan sosial kultural dalam kamus kompetensi manajerial dan sosial kultural berdasarkan Permenpan RB Nomor 38 Tahun 2017 kurang sesuai dengan uraian tugas beberapa JFT seperti Analis Kepegawaian, Pranata Komputer, Arsiparis dan Widyaiswara, dengan demikian kurang adil untuk menilai para pejabat fungsional tersebut. Ditemukan bahwa semakin tinggi jenjang jabatan fungsionalnya, semakin banyak pula aspek standar kompetensi yang tidak sesuai uraian tugas JFT. Kamus kompetensi tersebut lebih tepat digunakan untuk menilai kompetensi para pejabat struktural yang memiliki bawahan, dibandingkan bila dipakai untuk menilai pejabat fungsional tertentu yang tidak memiliki bawahan.
Temuan ini menjadi semakin meyakinkan ketika dikomparasikan dengan hasil penilaian menggunakan kamus kompetensi yang lain. Hasil studi kasus menunjukkan bahwa penggunaan kamus kompetensi manajerial sesuai Peraturan Kepala BKN Nomor 7 Tahun 2013 dalam menilai kompetensi JFT yang menggunakan ternyata lebih relevan, valid, akurat dan lebih memuaskan.
URGENSI ASAS NETRALITAS APARATUR SIPIL NEGARA DALAM PEMILIHAN UMUM DITINJAU DARI UNDANG-UNDANG NOMOR 5 TAHUN 2014 TENTANG APARATUR SIPIL NEGARA
Authors: Saputra Deni Jaya 
Published: August 2023

Partisipasi politik dalam negara demokrasi merupakan indikator implementasi penyelenggaraan kekuasaaan negara tertinggi yang absah oleh rakyat. Akan tetapi, tidak semua rakyat bisa berpartisipasi secara langsung dalam politik praktis dengan cara berpihak terhadap salah satu calon, menjadi tim sukses dan mengikuti setiap kegiatan kampanye. Rakyat dalam konteks ini adalah Aparatur Sipil Negara (ASN) yang diharuskan bersikap netral. Urgensi asas netralitas ASN dalam pemilu, yaitu: a. Independensi ASN terjaga sehingga ASN terbebas dari tekanan pemangku kebijakan di luar konteks kinerja; b. ASN terbebas dari politik balas budi; c. ASN fokus mengembangkan kompetensinya untuk mendapatkan promosi jabatan; d. Asas netralitas dapat meminimalisir korupsi, kolusi dan nepotisme dalam tubuh ASN; dan e. ASN mampu menjadi abdi negara yang profesional dalam pelayanan publik. Selain itu, manajemen ASN dilengkapi dengan sistem merit melalui kebijakan dan manajemen ASN yang didasarkan pada kualifikasi, kompetensi, dan kinerja secara adil dan wajar. Penerapan sistem merit relatif efektif untuk mewujudkan the right man of the right place sehingga menimalisir nepotisme.
Performance Appraisal of Women Self-Help Groups in Rolpa District of Lumbini Province, Nepal
Authors: Sen Elina , Ghadei Kalyan 
Published: August 2023

The present study was conducted in the Rolpa district of Nepal. For the purpose of the study, primary data has been collected using purposive cum multistage sampling technique. Rolpa district was selected purposively due to there was no such study conducted previously on performance appraisal of SHGs. A sample size of 150 self help group members was selected through multistage random sampling technique from two municipalities. The interview schedule was developed on the basis of objective and variables for data collection. The data was analyzed by using following statistical tools such as mean, standard deviation, percentage and correlation. This study revealed that, majority of the respondents observed under high category for the variables group cohesiveness(64 percent), collective action (65.33 percent), effective leadership (55.33 percent) group communication (50.67 percent) and group norms (76. 67 percent). The study depicts that majority of the SHGs had medium level of overall performance. It had reported most of the members had medium level of economic achievement after joining of SHGs. The variable like localite sources as information seeking behavior was found negative significant correlation whereas other independent variables exert positively with economic development of Self Help Groups.
Erythrocyte Indices in Asymptomatic Malaria Infected Pregnant Women
Authors: Martina Ngwu Amauche 
Published: August 2023

Background: Red blood cell changes are one of the most common complications in malaria and they play a very crucial role in malaria pathogenesis. Malaria infections are one of the common causes of maternal anaemia especially during pregnancy. The aim of this study was to determine red cell indices of pregnant women with asymptomatic malaria.
Place and Duration of Study: Department of Haematology and Antenatal Unit both of Enugu State University of Science and Technology Teaching Hospital, between June and September 2022.
Methodology: The study population consisted of 90 pregnant women (65 pregnant women positive to malaria parasite without symptoms and 25 pregnant women negative to malaria parasite) and 26 control non-pregnant women. For the whole study population, red cell indices which include hemoglobin (HGB), packed cell volume (PCV), red blood cell count (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width standard deviation (RDW-SD), red cell distribution width coefficient of variation (RDW-CV) were measured by automated haematology analyzer.
Results: In the asymptomatic malaria group (AMG), 21 (32.3%) had mild anaemia (HGB level 9.0-10.0 g/dl), 11 (16.9%) had moderate anaemia (HGB level 7.0-8.0 g/dl) and 2 (3.1%) had severe anaemia (HGB level <7.0 g/dl). Also in AMG group, the RDW-SD was 54.22 +/- 11.45 fl, whereas in control group it was 48.75 +/- 10.24 fl (p=0.002). Again in the AMG group the MCHC of those that had two pluses was 318.03 +/- 16.31 g/l, whereas in those that had one plus, it was 309 +/- 20.17 g/l. The comparison between the first, second and third trimester showed significant decrease in HGB (7.63 +/- 1.36 vs 11.64 +/- 0.72 g/dl) and PCV (26.98 +/- 5.14 vs 36.20 +/- 2.19 %) in third trimester compared to first trimester (p= <0.001, <0.001). whereas RDW-CV (18.96 +/- 5.04 vs 15.00 +/- 2.64 %) and RDW-SD (59.04 +/- 15.19 vs 49.16+/- 7.00 fl) (p= 0.002, 0.003) significantly increased in third trimester compared to first trimester
Conclusion: This study found anaemia in asymptomatic malaria infected pregnant women, significant decrease in haemoglobin and packed cell volume at third trimester, higher MCHC in those with two pluses of malaria and significant increase in red cell distribution width at third trimester.
Immunotherapy in the Treatment of Localized Genitourinary Cancers
Authors: Necchi Andrea , Faltas Bishoy M. , Slovin Susan F. , Meeks Joshua J. , Pal Sumanta K. , Schwartz Lawrence H. , Huang Richard S. P. , Li Roger , Manley Brandon , Chahoud Jad , Ross Jeffrey S. , Spiess Philippe E. 
Published: August 2023

ImportanceA true revolution in the management of advanced genitourinary cancers has occurred with the discovery and adoption of immunotherapy (IO). The therapeutic benefits of IO were recently observed not to be solely confined to patients with disseminated disease but also in select patients with localized and locally advanced genitourinary neoplasms.ObservationsKEYNOTE-057 demonstrated the benefit of pembrolizumab monotherapy for treating high-risk nonmuscle invasive bladder cancer unresponsive to bacillus Calmette-Guérin (BCG), resulting in recent US Food and Drug Administration approval. Furthermore, a current phase 3 trial (Checkmate274) demonstrated a disease-free survival benefit with the administration of adjuvant nivolumab vs placebo in muscle-invasive urothelial carcinoma after radical cystectomy. In addition, the recent highly publicized phase 3 KEYNOTE 564 trial demonstrated a recurrence-free survival benefit of adjuvant pembrolizumab in patients with high-risk localized/locally advanced kidney cancer.Conclusions and RelevanceThe adoption and integration of IO in the management of localized genitourinary cancers exhibiting aggressive phenotypes are becoming an emerging therapeutic paradigm. Clinical oncologists and scientists should become familiar with these trials and indications because they are likely to dramatically change our treatment strategies in the months and years to come.
Reliability‐based robust design optimization for building‐connecting inertial mass damper
Authors: Murase Mitsuru , Takewaki Izuru 
Published: August 2023

AbstractThis paper proposes an accurate and efficient reliability evaluation method for robust design optimization using a probabilistic approach. First, the validity of this method is verified using two benchmark functions. This method is then applied to the robust design optimization problem of building‐connecting damper parameters, and the effect of robust design is verified. The variation in the natural period and structural damping ratio of buildings is considered, and the criteria satisfaction rate (CSR) are directly evaluated using the response value calculated by time history response analysis.
Monitoring Melanoma Responses to STING Agonism and Focused Ultrasound Thermal Ablation Using Microneedles and Ultrasensitive Single Molecule Arrays
Authors: Dahis Daniel , Dion Michelle Z. , Cryer Alexander M. , Dosta Pere , Gilboa Tal , Alonso Mariana , Lewandowski Michael , Puigmal Núria , Taboada Gonzalo Muñoz , Azhari Haim , Ahmad Rushdy , Walt David R. , Artzi Natalie 
Published: August 2023

AbstractReal‐time monitoring of immune state and response to therapy can provide a means to stratify patients and increase the number of responders who will benefit from approved and emerging immunotherapies. The accessibility of immune cells in the skin provides an opportunity for local immune modulation as well as for noninvasive sampling of disease biomarkers in the skin interstitial fluid (ISF). Here, a monitoring strategy for melanoma immunotherapy is investigated by longitudinal sampling of biomarkers in the skin ISF using Hyaluronic acid (HA)‐based microneedles (MNs). Focused ultrasound ablation and delivery of nanoparticulate stimulator of interferon genes agonist are used as model immunotherapies. It is shown that this combination therapy induces potent inflammatory responses in a melanoma mouse model, promoting tumor elimination and immune memory formation. Indeed, quantifying soluble, protein‐based biomarkers following therapy using conventional immunoassay reveals a pronounced proinflammatory program in the tumor. However, conventional assays fail to detect the low concentration of biomarkers in plasma and in MN‐sampled ISF. It is shown that ultrasensitive single molecule arrays (Simoa) effectively detected proinflammatory biomarkers that are upregulated in response to the therapy in MN‐sampled ISF, in plasma, and in tumors, supporting the feasibility of monitoring melanoma immunotherapy using MNs.
A Bone Targeting Nanoparticle Loaded OGP to Restore Bone Homeostasis for Osteoporosis Therapy
Authors: Ma Shiqing , Xu Shendan , Li Minting , Du Yaqi , Tian Guangjie , Deng Jiayin , Zhang Wenyi , Wei Pengfei , Zhao Bo , Zhang Xuesong , Liu Zihao , Wang Yonglan 
Published: August 2023

AbstractRestoring bone homeostasis is the key to the treatment of osteoporosis. How to increase osteogenic ability or inhibit osteoclast activity has always been a topic of great concern. In recent years, short peptides with biological activity have received great attention in bone repair. However, the application of short peptides is still limited due to the lack of a stable and targeted delivery system. Poly(lactic‐co‐glycolic acid) (PLGA) nanoparticles modified by alendronate (AL) to transport osteogenic peptides (OGP) (AL‐PLGA@P NPs) are designed. Benefiting from the high affinity of AL for hydroxyapatite, AL‐PLGA@P NPs have the ability to target bone. In this delivery system, OGP that promotes osteogenesis synergizes with AL, which inhibits osteoclasts, to regulate bone homeostasis, which gives them more advantages in the treatment of osteoporosis. The data shows that nanoparticles can selectively deliver peptides to the bone surface without systemic toxicity. Moreover, nanoparticles can upregulate osteogenesis‐related factors (ALP, Runx‐2, and BMP2) and downregulate osteoclast‐related factors (TRAP and CTSK) in vitro. With AL‐PLGA@P NPs, bone microarchitecture and bone mass are improved in ovariectomized osteoporosis rats. Therefore, this study proposes a novel osteoporosis‐based drug system that effectively improves bone density.
Wood‐Derived Freestanding Carbon‐Based Electrode with Hierarchical Structure for Industrial‐Level Hydrogen Production
Authors: Li Di , Cheng Hao , Hao Xixun , Yu Guoping , Qiu Chuntian , Xiao Yanjun , Huang Hubiao , Lu Yingying , Zhang Bing 
Published: August 2023

AbstractThe sustainable and scalable fabrication of low‐cost, efficient, and durable electrocatalysts that operate well at industrial‐level current density is urgently needed for large‐scale implementation of the water splitting to produce hydrogen. In this work, an integrated carbon electrode is constructed by encapsulating Ni nanoparticles within N‐doped carbonized wood framework (Ni@NCW). Such integrated electrode with hierarchically porous structure facilitates mass transfer process for hydrogen evolution reaction (HER). Ni@NCW electrode can be employed directly as a robust electrocatalyst for HER, which affords the industrial‐level current density of 1000 mA cm−2 at low overpotential of 401 mV. The freestanding binder‐free electrode exhibits extraordinary stability for 100 h. An anion exchange membrane water electrolysis (AEMWE) electrolyzer assembled with such freestanding carbon electrode requires only a lower cell voltage of 2.43 V to achieve ampere‐level current of 4.0 A for hydrogen production without significant performance degradation. These advantages reveal the great potential of this strategy in designing cost‐effective freestanding electrode with monometallic, bimetallic, or trimetallic species based on abundant natural wood resources for water splitting.
Multifunctional High Entropy Alloys Enabled by Severe Lattice Distortion
Authors: Wang Hang , He Quanfeng , Gao Xiang , Shang Yinghui , Zhu Wenqing , Zhao Weijiang , Chen Zhaoqi , Gong Hao , Yang Yong 
Published: August 2023

AbstractSince 2004, the design of high entropy alloys (HEAs) has generated significant interest within the materials science community due to their exceptional structural and functional properties. By incorporating multiple principal elements into a common lattice, it is possible to create a single‐phase crystal with a highly distorted lattice. This unique feature enables HEAs to offer a promising combination of mechanical and physical properties that are not typically observed in conventional alloys. In this article, an extensive overview of multifunctional HEAs that exhibit severe lattice distortion is provided, covering the theoretical models that are developed to understand lattice distortion, the experimental and computational methods employ to characterize lattice distortion, and most importantly, the impact of severe lattice distortion on the mechanical, physical and electrochemical properties of HEAs. Through this review, it is hoped to stimulate further research into the study of distorted lattices in crystalline solids.
On‐Chip Monolithically Integrated Ultraviolet Low‐Threshold Plasmonic Metal‒Semiconductor Heterojunction Nanolasers
Authors: Sun Jia‐Yuan , Nguyen Duc Huy , Liu Jia‐Ming , Lo Chia‐Yao , Ma Yuan‐Ron , Chen Yi‐Jia , Yi Jui‐Yun , Huang Jian‐Zhi , Giap Hien , Nguyen Hai Yen Thi , Liao Chun‐Da , Lin Ming‐Yi , Lai Chien‐Chih 
Published: August 2023

AbstractThe metal‒semiconductor heterojunction is imperative for the realization of electrically driven nanolasers for chip‐level platforms. Progress in developing such nanolasers has hitherto rarely been realized, however, because of their complexity in heterojunction fabrication and the need to use noble metals that are incompatible with microelectronic manufacturing. Most plasmonic nanolasers lase either above a high threshold (101‒103 MW cm−2) or at a cryogenic temperature, and lasing is possible only after they are removed from the substrate to avoid the large ohmic loss and the low modal reflectivity, making monolithic fabrication impossible. Here, for the first time, record‐low‐threshold, room‐temperature ultraviolet (UV) lasing of plasmon‐coupled core‒shell nanowires that are directly grown on silicon is demonstrated. The naturally formed core‒shell metal‒semiconductor heterostructure of the nanowires leads to a 100‐fold improvement in growth density over previous results. This unprecedentedly high nanowire density creates intense plasmonic resonance, which is outcoupled to the resonant Fabry‒Pérot microcavity. By boosting the emission strength by a factor of 100, the hybrid photonic‒plasmonic system successfully facilitates a record‐low laser threshold of 12 kW cm−2 with a spontaneous emission coupling factor as high as ≈0.32 in the 340‒360 nm range. Such architecture is simple and cost‐competitive for future UV sources in silicon integration.