bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐term evaluation of peri‐implant keratinized mucosa stability after free epithelialized graft and keratinized mucosa shifting procedures: A retrospective study up to 13 years
Authors: Chen Ya‐Chi , Lai Yu‐Lin , Yen Jui‐Ying , Lin Yi‐Chun , Chen Hsuan‐Hung , Lee Shyh‐Yuan 
Published: July 2023

AbstractObjectivesThis study aimed to assess the risk of less than 2 mm keratinized mucosa (KM) width occurrence after free epithelialized graft (FEG) and keratinized mucosa shifting (KMS) procedures using survival analysis. In addition, KM dimensional changes were evaluated.Materials and MethodsThis study included 76 implants in 36 patients with insufficient KM (<2 mm). The implants underwent either FEG or KMS procedures. The mid‐buccal KM width was measured from surgery to the end of a one 13‐year follow‐up period.ResultsMean follow‐up durations were 9.2 ± 3.9 years for FEG and 6.3 ± 4.2 years for KMS. Two implants in FEG and nine implants in KMS exhibited a KM width of less than 2 mm during follow‐up. The hazard ratios for KMS compared to FEG were 6.48 (crude) and 6.54 (adjusted), both statistically significant (p < .05). The incidence rate of KMS (4.06%) was higher than that of FEG (0.63%), with an average incidence time of 3.38 years for KMS and 8.82 years for FEG post‐surgery. FEG showed a significant shrinkage within 6 months (33% ± 22%), whereas KMS demonstrated a gradual decrease over 13 years (34% ± 25%). FEG exhibited significantly greater width change than KMS during a 5‐year follow‐up (p < .05).ConclusionsFEG and KMS enhanced PIKM but exhibited different long‐term reduction patterns. FEG demonstrated rapid shrinkage, while KMS displayed gradual and continuous reduction. Moreover, KMS presented a higher risk and incidence of KM width less than 2 mm compared to FEG.
An Integrated Model of Collaborative Skill Acquisition: Anticipation, Control Tuning, and Role Adoption
Authors: Dimov Cvetomir M. , Anderson John R. , Betts Shawn A. , Bothell Dan 
Published: July 2023

AbstractWe studied collaborative skill acquisition in a dynamic setting with the game Co‐op Space Fortress. While gaining expertise, the majority of subjects became increasingly consistent in the role they adopted without being able to communicate. Moreover, they acted in anticipation of the future task state. We constructed a collaborative skill acquisition model in the cognitive architecture ACT‐R that reproduced subject skill acquisition trajectory. It modeled role adoption through reinforcement learning and predictive processes through motion extrapolation and learned relevant control parameters using both a reinforcement learning procedure and a new to ACT‐R supervised learning procedure. This is the first integrated cognitive model of collaborative skill acquisition and, as such, gives us valuable insights into the multiple cognitive processes that are involved in learning to collaborate.
The Multiple Perspectives Theory of Mental States in Communication
Authors: Heller Daphna , Brown‐Schmidt Sarah 
Published: July 2023

AbstractInspired by early proposals in philosophy, dominant accounts of language posit a central role for mutual knowledge, either encoded directly in common ground, or approximated through other cognitive mechanisms. Using existing empirical evidence from language and memory, we challenge this tradition, arguing that mutual knowledge captures only a subset of the mental states needed to support communication. In a novel theoretical proposal, we argue for a cognitive architecture that includes separate, distinct representations of the self and other, and a cognitive process that compares these representations continuously during conversation, outputting both similarities and differences in perspective. Our theory accounts for existing data, interfaces with findings from other cognitive domains, and makes novel predictions about the role of perspective in language use. We term this new account the Multiple Perspectives Theory of mental states in communication.
Association of obstructive sleep apnea with cardiometabolic diseases and cardiovascular mortality
Authors: Gao Jia , Shi Licheng , Zhu Xuanfeng , Liu Jiannan 
Published: July 2023

AbstractBackgroundObstructive sleep apnea (OSA) is one of the leading respiratory disorders, increasing the risk of cardiometabolic diseases. In the study, we investigated the association between OSA and the risk of cardiometabolic diseases and all‐cause and cardiovascular mortality in adults.MethodsParticipants were enrolled in the National Health and Nutrition Examination Survey. The baseline covariates were compared between participants with and without OSA status. Multivariable logistic regression was performed to explore the association between OSA and cardiometabolic diseases, while Cox proportional regression was performed for all‐cause and cardiovascular mortality.ResultsOSA status was positively associated with higher risks of cardiometabolic diseases, including hypertension (odds ratio [OR] 1.28, 95% confidence interval [CI] 1.14–1.45; p < 0.001), diabetes (OR 1.46, 95% CI 1.22–1.76; p < 0.001), and cardiovascular diseases (OR 1.29, 95% CI 1.08–1.54; p = 0.006) after adjusting for numerous covariates. However, no associations of OSA with all‐cause or cardiovascular mortality were observed.ConclusionOSA was associated with a higher risk of hypertension, diabetes, and cardiovascular diseases, but had no significant association with all‐cause or cardiovascular mortality in adults.
Transcriptomic evidence for Brachyury expression in the caudal tip region of adult Ptychodera flava (Hemichordata)
Authors: Arimoto Asuka , Nishitsuji Koki , Hisata Kanako , Satoh Noriyuki , Tagawa Kuni 
Published: July 2023

AbstractMost metazoans have a single copy of the T‐box transcription factor gene Brachyury. This gene is expressed in cells of the blastopore of late blastulae and the archenteron invagination region of gastrulae. It appears to be crucial for gastrulation and mesoderm differentiation of embryos. Although this expression pattern is shared by most deuterostomes, Brachyury expression has not been reported in adult stages. Here we show that Brachyury of an indirect developer, the hemichordate acorn worm Ptychodera flava, is expressed not only in embryonic cells, but also in cells of the caudal tip (anus) region of adults. This spatially restricted expression, shown by whole‐mount in situ hybridization, was confirmed by Iso‐Seq RNA sequencing and single‐cell RNA‐seq (scRNA‐seq) analysis. Iso‐Seq analysis showed that gene expression occurs only in the caudal region of adults, but not in anterior regions, including the stomochord. scRNA‐seq analysis showed a cluster that contained Brachyury‐expressing cells comprising epidermis‐ and mesoderm‐related cells, but which is unlikely to be associated with the nervous system or muscle. Although further investigation is required to examine the roles of Brachyury in adults, this study provides important clues for extending studies on Brachyury expression involved in development of the most posterior region of deuterostomes.
Survival of patients with Duchenne muscular dystrophy who underwent spinal deformity correction
Authors: Arshad Ayesha , Tsirikos Athanasios I. 
Published: July 2023

AbstractAimWe investigated survival rates after scoliosis correction in individuals with Duchenne muscular dystrophy (DMD) and evaluated factors that can affect them.MethodThis was a retrospective cohort study from 2000 to 2022 with a minimum 2‐year postoperative follow‐up. We reviewed the hospital records/spinal radiographs and analysed data with XLSTAT. Kaplan–Meier and multivariate Cox regression survival analysis was performed.ResultsForty‐three patients had a mean age at surgery of 14 years 5 months. Mean postoperative follow‐up was 10 years 10 months. There was no operative or 30‐day postoperative mortality in this group. Twenty‐four patients died because of cardiorespiratory failure. Median survivorship was 14 years 2 months, with the longest observed survival being 22 years 6 months given the limitation of the length of postoperative follow‐up. The degree of preoperative coronal imbalance and pelvic obliquity, as well as intraoperative blood loss, were factors that significantly affected survival. The impact of preoperative sagittal imbalance and extension of the fusion to the sacrum/pelvis trended towards significance. In contrast, age at surgery, preoperative/postoperative scoliosis, thoracic kyphosis, lumbar lordosis, scoliosis and pelvic obliquity flexibility or correction indices, postoperative coronal/sagittal balance, need of preoperative non‐invasive ventilation, preoperative feeding disorders, development of surgical complications, and length of hospital and intensive care unit stay were exposure variables that did not affect postsurgical survival in patients with DMD.InterpretationSurvival of up to two decades or more was possible among young patients with DMD after scoliosis correction. This was affected by factors that related to disease and deformity severity, as well as surgical morbidity.What this paper adds

There was no operative or 30‐day postoperative mortality in this group of patients with Duchenne muscular dystrophy (DMD) undergoing scoliosis correction.
Survival probabilities at 5‐year, 10‐year, 15‐year, and 20‐year intervals post‐surgery were 92%, 80%, 33%, and 12% respectively.
Scoliosis surgery achieved good deformity correction and a balanced spine that was maintained at follow‐up.
Respiratory failure, severe pneumonia, and left ventricular failure were the leading causes of death in the study participants.
Preoperative global coronal imbalance, pelvic obliquity, and intraoperative blood loss significantly predicted survival.
Factors that affected survival after scoliosis surgery were associated with perioperative morbidity and disease or deformity severity in the DMD group.
Initial case series of a novel sensing deep brain stimulation device in drug‐resistant epilepsy and consistent identification of alpha/beta oscillatory activity: A feasibility study
Authors: Chua Melissa M. J. , Vissani Matteo , Liu David D. , Schaper Frederic L. W. V. J. , Warren Aaron E. L. , Caston Rose , Dworetzky Barbara A. , Bubrick Ellen J. , Sarkis Rani A. , Cosgrove G. Rees , Rolston John D. 
Published: July 2023

AbstractObjectiveHere, we report a retrospective, single‐center experience with a novel deep brain stimulation (DBS) device capable of chronic local field potential (LFP) recording in drug‐resistant epilepsy (DRE) and explore potential electrophysiological biomarkers that may aid DBS programming and outcome tracking.MethodsFive patients with DRE underwent thalamic DBS, targeting either the bilateral anterior (n = 3) or centromedian (n = 2) nuclei. Postoperative electrode lead localizations were visualized in Lead‐DBS software. Local field potentials recorded over 12–18 months were tracked, and changes in power were associated with patient events, medication changes, and stimulation. We utilized a combination of lead localization, in‐clinic broadband LFP recordings, real‐time LFP response to stimulation, and chronic recordings to guide DBS programming.ResultsFour patients (80%) experienced a >50% reduction in seizure frequency, whereas one patient had no significant reduction. Peaks in the alpha and/or beta frequency range were observed in the thalamic LFPs of each patient. Stimulation suppressed these LFP peaks in a dose‐dependent manner. Chronic timeline data identified changes in LFP amplitude associated with stimulation, seizure occurrences, and medication changes. We also noticed a circadian pattern of LFP amplitudes in all patients. Button‐presses during seizure events via a mobile application served as a digital seizure diary and were associated with elevations in LFP power.SignificanceWe describe an initial cohort of patients with DRE utilizing a novel sensing DBS device to characterize potential LFP biomarkers of epilepsy that may be associated with seizure control after DBS in DRE. We also present a new workflow utilizing the Percept device that may optimize DBS programming using real‐time and chronic LFP recording.
VLSI implementation of image compressor using probabilistic run length coding
Authors: Boddu Mahesh , Mandal Soumitra Kumar 
Published: July 2023

AbstractMultimedia applications, such as image processing including image and video transfer, heavily rely on reduction. The traditional device methods to picture reduction use more space, energy, and processing time. The majority of current efforts use the Golomb‐Rice encoding, due to its larger memory requirement and higher computing difficulty. So, this research concentrated on hardware design‐oriented probability run length (PRL) coding technique based on lossless colour image compression. The block truncation coding (BTC) features of the compression process are used by the suggested PRL method. The proposed image compression hardware consists of various modules such as a Parameter calculator, fuzzy table, bitmap generator, BTC parameters training, prediction, and error control, and PRL‐based finite state machine (PRL‐FSM). The proposed image compressor utilizes the parameter calculator block, which estimates the block type based on the image pixel intensities for each sub‐block. Thus, each block of the image is compressed by using a new block type and generates a variable block size. The proposed method utilizes the PRL‐BTC encoding method, which also calculates the probability of error between the compressed image to the test image. The process is iterated until the performance trade‐off between hardware cost and compression ratio (CR) is achieved. Hence, both smooth regions and non‐smooth regions of images are perfectly compressed by the probability‐based block selection. The simulation results show that the proposed method resulted in a better area, power, delay metrics, peak signal‐to‐noise ratio (PSNR), and CR compared to the state of art approaches.
How does the pore solution chemistry influence the passivation of reinforced alkali‐ and salt‐activated slag materials?
Authors: Gevaudan Juan Pablo , Timounay Yousra , Mayrhofer Leonhard , Zarshenas Mohammad , Moseler Michael 
Published: July 2023

AbstractService life predictions of reinforced concrete structures are underpinned by the passivation film chemistry, structure, and thickness. In this work, we present how the formation of passive films at the steel–concrete interface of reinforced alkali‐ and salt‐activated slag materials can be affected by the pore solution chemistry, namely, pH, Eh, and chemical composition. Thermodynamic simulations are used to illustrate the time‐dependent changes to the pore solution chemistry, where estimated electrical conductivities of the pore solution are used as a single‐value parameter to understand the solution complexity and capacity for charge transfer. A set of passivation reactions are proposed to understand the effects of OH− and HS− (reduced sulfur species) competition on the passivation pathways. These passivation reactions become more complex considering that a reducing pore solution might not establish until 3 days into the curing process—a crucial factor explaining the significant differences in the phase composition of passive films of activated slag materials (FeOOH, FeS). This study sheds light on recent progress in understanding these initial passivation reactions, emphasizing the essential role of material design and, therefore, the pore solution chemistry of these cements, along with significant insights for vital research and development concerning the corrosion durability of activated slag materials.
High‐performance Cu2O‐based photocatalysts enabled by self‐curling nanocelluloses via a freeze‐drying route
Authors: Wang Zezhen , Xin Xipeng , Xu Yifeng , Liu Qingdong , Zhu Yiqiu , Song Xuefeng , Liu Zhen , Xu Jijin , Liu Jing , Gao Lian 
Published: July 2023

AbstractEnhancing the photocatalytic stability of Cu2O in the degradation of tetracycline is a great challenge in combating environmental water pollution because it is prone to deactivation by photocorrosion in aqueous environment. In this study, Cu2O/cellulose microfiber aerogel is synthesized through freeze‐drying, utilizing the self‐curling effect of cellulose and then calcined to produce Cu2O/C composite aerogel. The derived Cu2O/C composite aerogel features hollow carbon microfibers anchored with Cu2O nanocubes. Due to the curling structure and conductivity of the carbon microfibers, the photodegradation efficiency of the obtained Cu2O/C composite aerogel for tetracycline is drastically improved to 97.3% under 120 min of visible‐light irradiation, and remains a cycling photodegradation rate of 84.3% after 10 cycles. The Cu2O/C composite aerogel shows remarkable strategies for designing and constructing Cu2O‐based photocatalyst in the practical photodegradation of tetracycline under visible‐light exposure.
Atrial mechanical contraction and ambulatory atrioventricular synchrony: Predictors from the OPTIVALL study
Authors: Briongos‐Figuero Sem , Estévez Paniagua Álvaro , Sánchez Hernández Ana , Jiménez Loeches Silvia , Gómez Mariscal Eloy , Vaqueriza Cubillo David , Muñoz‐Aguilera Roberto 
Published: July 2023

AbstractIntroductionThe role that preprocedural factors have on atrioventricular synchrony (AVS) provided by leadless pacemakers requires investigation.Methods and ResultsWe aimed to assess the correlation between mitral inflow echocardiographic parameters and p‐wave morphology with the accelerometer A4 signal amplitude. We also sought to identify clinical and echocardiographic predictors of optimal ambulatory AVS (≥85% of cardiac cycles).Forty‐three patients undergoing Micra AV implant from June 2020 to March 2023 were prospectively enrolled. Baseline echocardiogram and 12‐lead resting ECG were performed. Device follow‐up was scheduled at 24 h, 1, 3, and 6 months and yearly after the implant. Ambulatory AVS was studied with a 24 h Holter monitor performed at 3 months follow‐up in 35 patients who remained in VDD mode.A4 signal amplitude at 1 month correlated to peak A wave velocity (r = .376; p = .024) at echocardiogram, but no relationship was found with peak A' wave velocity, E/A, or E'/A' ratio. P‐wave amplitude in lead I and aVF correlated to A4 signal amplitude at 1‐ and 3‐months follow‐up, respectively.Median AVS during 24 h of daily activities was 85.6 ± 7.6% and remained stable up to 100 bpm. Twenty‐three out of 35 patients (65.7%) reached optimal ambulatory AVS. There was no association between mitral inflow echocardiographic parameters and optimal AVS. Diabetes (OR: 0.05, 95% CI: 0.01−0.47; p = .009) and chronic obstructive pulmonary disease (COPD) (OR: 0.06, 95% CI: 0.01−0.63; p = .019) strongly predicted ambulatory AVS <85%.ConclusionsDiabetes and COPD should be considered when selecting candidates for Micra AV. Measurements of pulsed wave Doppler mitral inflow do not systematically reflect the behavior of the A4 signal amplitude.
Differences in the ultrastructure of neurons in the spinal ganglion and dorsal rootlet between rats treated with cisplatin only versus co‐administration with a sphingosine 1‐phosphate receptor 2 agonist in attenuating neuropathy and allodynia
Authors: Chayaburakul Kanokporn , Ong Wei Yi , Herr Deron R. , Kobutree Phetnarin , Chantra Kraisri 
Published: July 2023

AbstractBackground and AimsCisplatin is a chemotherapeutic agent for many types of cancer. The neurotoxicity of cisplatin includes neuropathy and allodynia. We aimed to study structural changes by using CYM54‐78, attenuating cisplatin‐induced neuropathy and blocking the pathogenesis in neurons, and promoting axonal regeneration.MethodsTEM (transmission electron microscopy) was used to distinguish ultrastructural changes in dorsal root ganglion (DRG) and dorsal rootlets (DR) between rats treated with cisplatin alone and rats co‐treated with cisplatin and sphingosine ‐1‐phosphate receptor2 (S1P2) agonist, CYM‐5478.ResultsIn DRG of rats treated with cisplatin alone, TEM micrographs showed necrosis and apoptotic cells. Neuronal cytoplasm showed numerous vacuole (stage C) and swelling (stage B➔C) mitochondrial degeneration. Neurons in DRG from cisplatin+CYM‐5478 group showed a higher percentage of healthy mitochondria (from 5.3% to 75.6%) than those treated with cisplatin alone. DR of cisplatin only group showed abnormal axoplasm, axolemma, and focal detached myelin sheaths, especially in Aδ (fast pain) and Aβ (touch) fibers, and revealed collateral branches that sprouted from Aβ fibers, which is characteristic of allodynia. Moreover, vasoconstriction was observed in DRG and DR. Rats in cisplatin+CYM‐5478 group showed not only fewer abnormal structures than those in cisplatin only group, but also showed Bands of Büngner and onion bulb‐like structures, which are characteristic of nerve regeneration.InterpretationTogether with our previous study, showed that CYM‐5478 attenuated neuropathy and allodynia in a rat model of cisplatin‐induced neuropathy, these results suggest S1P2 agonists as a potential approach the for treatment of cancer due to the reduction of side effects of cisplatin.
Impact of postnatal weight gain on brain white matter maturation in very preterm infants
Authors: Bobba Pratheek S. , Weber Clara F. , Higaki Adrian R. Acuna , Mukherjee Pratik , Scheinost Dustin , Constable R. Todd , Ment Laura , Taylor Sarah N. , Payabvash Seyedmehdi 
Published: July 2023

AbstractBackground and PurposeVery preterm infants (VPIs, <32 weeks gestational age at birth) are prone to long‐term neurological deficits. While the effects of birth weight and postnatal growth on VPIs’ neurological outcome are well established, the neurobiological mechanism behind these associations remains elusive. In this study, we utilized diffusion tensor imaging (DTI) to characterize how birth weight and postnatal weight gain influence VPIs’ white matter (WM) maturation.MethodsWe included VPIs with complete birth and postnatal weight data in their health record, and DTI scan as part of their predischarge Magnetic Resonance Imaging (MRI). We conducted voxel‐wise general linear model and tract‐based regression analyses to explore the impact of birth weight and postnatal weight gain on WM maturation.ResultsWe included 91 VPIs in our analysis. After controlling for gestational age at birth and time between birth and scan, higher birth weight Z‐scores were associated with DTI markers of more mature WM tracts, most prominently in the corpus callosum and sagittal striatum. The postnatal weight Z‐score changes over the first 4 weeks of life were also associated with increased maturity in these WM tracts, when controlling for gestational age at birth, birth weight Z‐score, and time between birth and scan.ConclusionsIn VPIs, birth weight and post‐natal weight gain are associated with markers of brain WM maturation, particularly in the corpus callosum, which can be captured on discharge MRI. These neuroimaging metrics can serve as potential biomarkers for the early effects of nutritional interventions on VPIs’ brain development.
The Slut‐Shaming Instrument: Preliminary validation, correlates, and links with psychological distress among adolescent girls
Authors: Martin‐Storey Alexa , Dirks Melanie , Paquette Geneviève , Boutin Stéphanie , Dryburgh Nicole S. J. , Leduc Karissa , Bolduc Marie‐Louise , Temcheff Caroline 
Published: July 2023

AbstractDespite social awareness of the problem of slut‐shaming for adolescent girls, no existing measure captures this construct. Using data from a sample of 202 girls from Québec, Canada (ages 14–17; 68% White), preliminary validation is provided for the Slut‐Shaming Instrument, a seven‐item measure of negative peer experiences related to being perceived as too sexually active, sexualized, or flirtatious. The measure showed strong psychometric properties including good reliability and factor structure, expected associations with daily experiences of slut‐related victimization and sexual harassment, and links with number of sexual partners and other forms of peer victimization. Slut‐shaming was associated with distress accounting for these other forms of victimization (including sexual harassment), suggesting the pertinence of addressing this type of gender‐based victimization.