bluuebunny/crossref_metadata_2025_split huggingface dataset:
UGC 4211: A Confirmed Dual Active Galactic Nucleus in the Local Universe at 230 pc Nuclear Separation
Authors: Koss Michael J. , Treister Ezequiel , Kakkad Darshan , Casey-Clyde J. Andrew , Kawamuro Taiki , Williams Jonathan , Foord Adi , Trakhtenbrot Benny , Bauer Franz E. , Privon George C. , Ricci Claudio , Mushotzky Richard , Barcos-Munoz Loreto , Blecha Laura , Connor Thomas , Harrison Fiona , Liu Tingting , Magno Macon , Mingarelli Chiara M. F. , Muller-Sanchez Francisco , Oh Kyuseok , Shimizu T. Taro , Smith Krista Lynne , Stern Daniel , Tello Miguel Parra , Urry C. Megan 
Published: January 2023

Abstract
We present multiwavelength high-spatial resolution (∼0.″1, 70 pc) observations of UGC 4211 at z = 0.03474, a late-stage major galaxy merger at the closest nuclear separation yet found in near-IR imaging (0.″32, ∼230 pc projected separation). Using Hubble Space Telescope/Space Telescope Imaging Spectrograph, Very Large Telescope/MUSE+AO, Keck/OSIRIS+AO spectroscopy, and the Atacama Large Millimeter/submillimeter Array (ALMA) observations, we show that the spatial distribution, optical and near-infrared emission lines, and millimeter continuum emission are all consistent with both nuclei being powered by accreting supermassive black holes (SMBHs). Our data, combined with common black hole mass prescriptions, suggest that both SMBHs have similar masses,

log

M

BH

/

M

⊙

∼ 8.1 (south) and

log

M

BH

/

M

⊙

∼ 8.3 (north), respectively. The projected separation of 230 pc (∼6× the black hole sphere of influence) represents the closest-separation dual active galactic nuclei (AGN) studied to date with multiwavelength resolved spectroscopy and shows the potential of nuclear (<50 pc) continuum observations with ALMA to discover hidden growing SMBH pairs. While the exact occurrence rate of close-separation dual AGN is not yet known, it may be surprisingly high, given that UGC 4211 was found within a small, volume-limited sample of nearby hard X-ray detected AGN. Observations of dual SMBH binaries in the subkiloparsec regime at the final stages of dynamical friction provide important constraints for future gravitational wave observatories.
Analytical quality by design-based RP-HPLC method for quantification of pioglitazone and candesartan cilexetil in bilayer tablet and its forced degradation studies
Authors: Kola Hephzibah , Shanmugasundaram Sangeetha 
Published: January 2023

Aim: The current project involves developing an RP-HPLC method for simultaneous quantification of Candesartan Cilexetil and Pioglitazone based on analytical quality by design (AQbD).
Materials and methods: When analysed in the Design Expert application, the critical method parameters were systematically refined using Central Composite Design and contours were derived for significant variables. A contour plot has been used to discover the technique operable design region that governs response variation, which is then empirically tested.
Results: Successful chromatographic separation of title analytes was achieved on kromasil C18 (150 × 4.6 mm, 5 µm) column at 30 °C with mobile phase comprising 60% 20 Mm Potassium dihydrogen orthophosphate and 40% acetonitrile (v/v), isocratic elution pattern, 0.9 mL/min flow rate, and UV detection at 220 nm. The linear model for Candesartan Cilexetil was from 4 to 24 µg/ mL and Pioglitazone at 7.5–45 µg/ mL, respectively.
Conclusion: The method met all the ICH Q2 (R1) validation criteria. The current approach aided for analysing simultaneous drugs can be expanded into quantifying drugs in biological matrix predominance with maximum recovery.
Wild host fruit–niche diversity of Drosophila suzukii in lowbush blueberry agroecosystems in Saguenay-Lac-Saint-Jean, Québec, Canada
Authors: Guay Jean-Frédéric , Champagne-Cauchon William , Fournier Valérie , Cloutier Conrad 
Published: January 2023

Abstract
Understanding movements of Drosophila suzukii (Diptera: Drosophilidae) into berry fruit crops from wild-fruit hosts in borders of semi-natural agroecosystems, such as lowbush blueberry, is important to determining harvesting time and managing wild-fruit diversity near crops. This study aimed to inventory the wild-fruit hosts associated with lowbush blueberry (Ericaceae) production in Québec, Canada, near the limits of lowbush blueberry’s eastern North American range. We also tested the hypothesis that fruit traits of berry fruit species present in or near lowbush blueberry fields might explain field infestation levels. Flies of both sexes emerged from five wild-fruit species in 2016, to which six more species were added in 2017. The most productive wild-fruit hosts were Cornus canadensis (Cornaceae) and Aralia hispida (Araliaceae) (> 100 emerged flies/100 g of fruit) in 2016, to which Prunus pensylvanica (Rosaceae) and Rubus idaeus (Rosaceae) were added in 2017. Among nine variables considered in statistical modelling (fruit size, sugar content, and reflected colour bands) and taxonomic family (a nominal variable), none could explain field infestation levels over two years. In lab tests comparing fruits of Cornus canadensis, a common weed within fields, and lowbush blueberries, mated D. suzukii females laid twice as many eggs on blueberries, but both species were equally suitable for development.
Health-related quality of life of parents of children with beta-thalassemia major attending a tertiary care institution in Eastern India
Authors: Chandra Archi , Mallik Sarmila , Chakrabarti Soma , Bhattacharyya Nabanita 
Published: January 2023

Context:
Chronic diseases such as beta-thalassemia major among children impact their parents in various ways, as they face continuous stress and strain while striving to provide their children with a best possible care. Literature related to health-related quality of life (HRQoL) among parents of children with beta-thalassemia major are limited among Indian population.

Aims:
This study aimed to assess the HRQoL of parents of children with beta-thalassemia major attending a tertiary care institution in Eastern India and its various correlates.

Settings and Design:
This cross-sectional study was conducted at a tertiary care institution in Eastern India.

Materials and Methods:
A sample size of 192 was selected using the simple random sampling among parents with children suffering from beta-thalassemia major who fulfilled the inclusion criteria. Study participants were interviewed regarding different variables and their HRQoL, using a predesigned, pretested, and semi-structured schedule and the Short Form 36 Health survey, respectively, after obtaining ethical clearance from the Institutional Ethics Committee and informed consent from them.

Statistical Analysis Used:
Data were entered in MS Excel and analyzed using IBM SPSS 20.0 version (Armonk, NY: IBM Corp).

Results:
The mean HRQoL score was found to be 38.7 ± 11.3 with an interquartile range of 23–59.7. The Spearman's rho correlation matrix showed that HRQol of parents is weakly positively correlated with the educational status of the father of the child (r = 0.2), educational status of the mother of the child (r = 0.1), family history of thalassemia (r = 0.2), ongoing treatment (r = 0.1), and duration of blood transfusion (r = 0.2).

Conclusions:
Hence, we can conclude that HRQoL of parents of beta-thalassemia major children was correlated with the educational status of the father and mother, family history of thalassemia, ongoing treatment, and duration of blood transfusion.
Comparative study between aspiration followed by Intralesional triamcinolone Injection, mixture of triamcinolone and hyaluronidase and surgical excision for the treatment of forearm ganglion in a medical college hospital
Authors: Hassan Yaqoob , Rather Ajaz Ahmad , Peer Javid Ahmad 
Published: January 2023

Background:
Ganglionic cysts are benign tumors of forearm commonly encountered in our day-to-day outdoor practice. This study compares the efficacy, safety, and recurrence rates of triamcinolone, a triamcinolone hyaluronidase mixture, and surgical excision for the treatment of forearm ganglion in a medical college hospital.

Materials and Methods:
This prospective comparative study was carried out at the SKIMS, Medical College, Hospital, over a period of 3 years. Between January 2018 and January 2021, 96 subjects with forearm ganglion were included and treated in three groups – Group A included patients who had aspiration and injection of triamcinolone; Group B patients had aspiration and injection of mixture of triamcinolone and hyaluronidase; and Group C patients underwent excision under anesthesia. The data were collected and analyzed using SPSS software 22.

Results:
Among 96 patients who met the inclusion criteria, the mean age was 35.74 years, with a male: female ratio of 0.63. The swelling was the most common clinical presentation recorded in 100% of patients. Swelling with symptoms such as pain and paresthesia was present in 59.38% of the patients, dissatisfaction with cosmetic appearance in 55.21% of the patients, and 36.46% subjects had apprehension of sinister lesion (malignant tumor). 47.92% of patients had aspiration and injection of triamcinolone (Group A), 43.75% of patients had aspiration and injection of triamcinolone-hyaluronidase mixture (Group B), and 8.33% of patients underwent surgical excision (Group C). The difference in recurrence rate was significantly lower in the Group B patients (15.22%) than in the Group A patients (2.38%) (P ≤ 0.05). We observed 100% success rate after surgical excision. No major postprocedure complications occurred in any of the patients.

Conclusion:
Aspiration and intracystic instillation of a triamcinolone-hyaluronidase mixture is a simple, effective, and safe treatment for ganglion with low recurrence rates. Following an unsuccessful primary therapy of aspiration and injection, surgical excision yielded excellent results.
Performance of the Health System Network in Formosa, Argentina, in the Diagnosis of Leprosy
Authors: Arnaiz María R. , Abarca Daniela Tobar , Santini María S. , Franco José I. , Arzamendia Lucila , Recalde Hugo C. , Bruzzone Octavio A. 
Published: January 2023

ABSTRACT.
Leprosy is a chronic, neglected tropical infectious disease, currently endemic in Formosa, a province in northwestern Argentina. To analyze the performance, distribution, and effectiveness of the health system in leprosy diagnosis in Formosa, we estimated the trend of the number of new cases of leprosy diagnosed between 2002 and 2019 and estimated a forecast for 2022 at the primary health care centers (PHCCs) of at the first level of care (1stLC), at district hospitals (DHs) of the second level of care (2ndLC), high-complexity hospitals at the third level of care (3rdLC), and in rural and urban areas. The general trend was calculated based on the new cases detection rate (NCDR) using the autoregressive–moving average model (ARMA). The 1stLC, 2ndLC, and 3rdLC and the rural/urban variables were assessed using a proportional Bayesian trend ARMA (TrARMA) model. A predictive model was used for estimated forecasts. Markov-Monte Carlo chains were applied with A Metropolis-Hastings’s algorithm. The highest median proportion (Mp) of new cases of leprosy was diagnosed at the 2ndLC (Mp, 0.67; 97.5% credibility interval [CI] [0.56–0.77]), at the 3rdLC (Mp, 0.11; 97.5% CI [0.08–0.15]), and in urban areas (urban median proportion (uMp), 0.86; 97.5% CI [0.83– 0.88]), whereas the lowest proportion of new cases was diagnosed at the 1stLC (Mp, 0.082; 97.5% CI [0.061–0.108]) and in rural areas (rural median proportion (rMp), 0.13; 97.5% CI [0.11–0.16]). Our model predicts for 2022 that a median number of new cases of leprosy of 19.70 will be diagnosed in urban areas (97.5% CI [15.94–23.80]), and will continue to be diagnosed at the 2ndLC (median number of cases, 15.33; 97.5% CI [12.40–10.52]) and 3rdLC (median number of cases, 2.43; 97.5% CI [1.97–2.94]).
Active Trachoma Prevalence and Related Variables among Children in a Pastoralist Community in Southern Ethiopia in 2021: A Community-Based Cross-Sectional Study
Authors: Tuke Dedefo , Etu Edao , Shalemo Endale 
Published: January 2023

ABSTRACT.
An estimated 30% of trachoma burden is borne by Ethiopia. Data on the prevalence of active trachoma and related factors in a pastoralist population are currently lacking. Additionally, no research has been conducted in the Oromia, Guji Zone of the Liben District. A community-based cross-sectional study was conducted among 538 children 1–9 years old in the pastoralist community of the Liben District from March 1 to April 30, 2021. A multistage systematic sampling method was applied to choose the sample. A structured questionnaire and WHO’s trachoma grading scheme were used to identify active trachoma. Bivariate and multivariable logistic regression models were fitted to determine associated factors. An adjusted odds ratio with 95% confidence interval was calculated to decide the level of significance: 157 (29.2%) (95% CI: 24.9, 33.1) of children had clinical signs of active trachoma, 103 (66%) had trachomatous follicles, 41 (26%) had trachomatous intense, and 13 (8%) had both. There was an independent relationship between active trachoma and open defecation (adjusted odds ratio [AOR]: 2.75; 95% CI: 1.24, 6.09), defecating outside close to a house (AOR: 2.5; 95% CI: 1.07, 6.08), not having a latrine (AOR: 3.70; 95% CI: 1.60, 8.60), children who did not wash their faces with soap (AOR: 1.85; 95% CI: 1.10, 3.07), and being in a widowed household (AOR: 3.26; 95% CI: 1.57, 6.63). The study’s findings revealed that about one-third of the children had clinical signs of trachoma. Research indicates that trachoma is a major concern for children in rural communities. Therefore, attention to trachoma control with antibiotics, facial hygiene, and environmental sanitation is strongly encouraged.
Analisis Perbandingan Algoritma NGG dan GGHN pada Frekuensi Hasil Enkripsi
Authors: Siregar Farid Akbar , Rizka Ade , Siregar Annisa Fadillah 
Published: January 2023

Data and information in the development of digital technology have an important role. Every activity or activity that uses digital technology is related to data and information, so information security and data confidentiality are very important. To maintain information security and data confidentiality, protection with cryptographic techniques is needed. Cryptographic techniques are related to encryption, which is where the process of scrambling data is carried out and hiding data with a key system, while decryption is the process of changing the condition of the data to its original form so that it is easy to understand. There are obstacles and problems ini digital communication, so cryptographic techniques are needed that have higher level of security and can be applied in digital communications. To determine the level of security in cryptographic techniques required frequency anlysis. Frequency analysis on the NGG and GGHN algorithms is carried out to determine the level of information security based on the results of data encryption. BAse on the testing process on the NGG and GGHN algorithms, it will be known that the frequency of characters in the text varies. The more characters used in the key will affect the level of information security. The NGG algorithm has a higher level of security than the GGHN algorithm with a precentage difference of 0.000299967%. If the frequency of occurrence of characters in the message text that has been encrypted is more frequent or higher, then the level of information security in the message is lower and the password is easier to crack.
Land Price Classification Map in Jakarta Using Random Forest and Ordinary Kriging
Authors: Chandrasa Naufal Alvin , Prasetyowati Sri Suryani , Sibaroni Yuliant 
Published: January 2023

This research provides information about land prices in Jakarta by classifying using the Random Forest method. Where Random Forest is a data mining technique that is usually used to perform classification and regression. Random Forest is one of the best classification methods. It is found that classification accuracy will increase dramatically as a result of voting to select class types and ensemble tree growth. The method helps in providing information about the classification of land prices with the class of land prices per meter less than IDR 15 million, land prices per meter with a price range of IDR 15 to 25 million and land prices per meter more than IDR 25 million. With a fairly good accuracy of 82%, this method can classify where the permeter land price data that is tested will match the predicted classification accurately. Classification is performed on unbalanced data which is then oversampled using the ADASYN method. Assisted by doing spatial interpolation with the Ordinary Kriging method using Semivariogram, information about the classification of land prices can be seen on the distribution of the Jakarta area map. Ordinary Kriging can predict the estimated price per meter of land around the area of land that has a known price. The Root Mean Square Error (RMSE) results of the best Semivariogram model are obtained from the lowest RMSE value, namely the Spherical model with a value of 1.014896e7. The contribution of this research is to provide information about a reliable classification method, namely Random Forest and Ordinary Kriging performance as a spatial analysis method that can predict land prices per meter at unknown points so as to provide information about the distribution of land prices in Jakarta with each price class.
Rancang Bangun Alat Pemisah Buah Kopi Berdasarkan Tingkat Kematangan Menggunakan Sensor TCS3200 Berbasis Android
Authors: Salamah Irma , Muliawati Mega , Fadhli Mohammad 
Published: January 2023

The processing of coffee before it can be drunk goes through a long process, namely harvesting coffee fruits that have matured either by machine or by hand, then processing coffee fruits and drying before they become spindle coffee. Before the roasting process, the coffee fruit is chosen first to be ripe in order to produce the last result of the best coffee process. After the coffee fruit is selected, the next process is stripping the ripe coffee fruit in order to speed up the post-harvest process of the coffee fruit. Harvesting will also affect the quality and taste of coffee, harvesting is usually done when the coffee fruit that has matured physiologically which is characterized by the color of the fruit skin becomes a red color. At the level of maturity of coffee fruits still occurs not simultaneously so that the harvesting process takes a long time. When the harvest period comes, the separation of coffee fruits is still mostly done manually by picking them in a simultaneous way. This simultaneous separation of coffee fruits makes the mixing of coffee fruits that are still raw, half-ripe, and already ripe, causing poor taste quality, that's why the author got the idea to make a tool that can make the coffee harvesting process simpler and more efficient, namely a coffee fruit separator tool based on maturity level aims to find out how the tool performs in detecting coffee fruits based on maturity levels and how performance from a coffee fruit peeler. This tool can produce separate coffee fruits based on the degree of maturity, namely in the category of ripe, half-ripe and unripe. When coffee fruits that are still not separated between ripe, half-ripe and raw, are placed on the conveyor, the TCS3200 color sensor will detect the coffee fruit according to its color. The coffee fruit will be sorted automatically into a container that has been provided which is controlled by a servo motor that has been pre-programmed by Arduino. After the data from the coffee fruit separator has been read by the sensor, the Arduino will send the data to android via bluetooth connection. Furthermore, red coffee fruits or coffee fruits in the ripe category will proceed to the stripping stage. At the stripping stage, ripe coffee fruits will be peeled on a peeling machine controlled by a servo motor
Sentiment Analysis Against IndiHome and First Media Internet Providers Using Ensemble Stacking Method
Authors: Muhammad Fikri Arya Rafif , Jondri Jondri , Astuti Widi 
Published: January 2023

Customer satisfaction is one of the factors that can be used to measure the success of service in a company. In the era of the 2000s until now, internet service providers have continued to grow throughout the world, including in Indonesia. IndiHome and First Media are companies that provide internet services that make it easy for the public to communicate and obtain information. With many uses of IndiHome and First Media internet services, there are often several obstacles that cause various responses from users. Users usually channel these responses to IndiHome or First Media customer care on Twitter. The dataset for this study was obtained from Twitter using the Twitter API and the Tweepy library. The dataset that has been collected is 6.962 tweets for the IndiHome dataset and 8,089 tweets for the First Media dataset. This study conducts sentiment analysis using the Ensemble Stacking with three base classifiers and a meta classifier. The base classifier used is Naïve Bayes, K-Nearest Neighbor, and Decision Tree, while the meta classifier used is Logistic Regression. This study uses the term frequency-inverse document frequency (TF-IDF) to determine the frequency value of a word in a document. This study uses two test scenarios: testing without oversampling and testing with oversampling on the dataset. The results show that Ensemble Stacking with term frequency-inverse document frequency feature extraction produces the highest accuracy, with an accuracy value of 88.27% on the IndiHome dataset and 92.56% on the First Media dataset by oversampling on both datasets.
Bissexualidade na pesquisa: estudo de revisão sistemática da literatura
Authors: Longhitano Bianca , Bortolozzi Ana Claudia 
Published: January 2023

A sexualidade é um fenômeno humano e complexo e sua compreensão pode variar de acordo com o contexto em que se manifesta. Esta pesquisa teve por objetivo estudar como a bissexualidade tem sido tratada por meio de uma revisão sistemática da literatura. As bases de dados foram Science, Psycinfo, Pubmed, Scopus, Scielo e Pepsic com o descritor de busca “bissexualidade”. Os critérios de inclusão foram possuir a palavra “bissexualidade” no título, publicações entre 2000 e 2019 e estarem em inglês ou português. Foram localizados 31 documentos, excluídos 4 e resultantes 27 para análise de conteúdo. Destes, 26 eram de língua inglesa, e apresentam dados referentes às vulnerabilidades específicas e relevantes deste grupo. A pesquisa apresenta que os dados sobre essa população são escassos, contribuindo para a invisibilidade do grupo.
Mulheres migrantes do sul global no contexto pandêmico em Portugal
Authors: Ribeiro Renata Maria Franco 
Published: January 2023

Este relato faz parte das notas de campo da minha pesquisa do curso de mestrado em antropologia nos anos de 2020 e 2021 na freguesia Vale da Amoreira no Concelho de Moita (Portugal). Propomos analisar os percursos e cotidianos das mulheres guineenses a partir da agencia e redes com reflexo no habitus feminino que mobiliza as redes sociais, atuando num quadro de microliberdades e microressistências no cerne da emancipação e cidadania, no contexto pandemia da Covid-19. Destaco que estas mulheres possuem percursos migratórios distintos e oriundas de sociedades com códigos culturais de pertenças, sociabilidades diversas. Traremos as experiências de duas partícipes. A pesquisa se deu no campo das migrações e transnacionalismo dialogando com epistemologias decoloniais e feministas. Constatou-se a participação e engajamentos das mulheres guineenses no enfrentamento aos constrangimentos na migração e em tempos de crise pandémica no estado português.