bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Korelasi antara Kecemasan dan Kejadian Preeklamsia pada Ibu Hamil
Authors: Saddam Muhammad , Saharuddin Saharuddin , Yunus Purnamaniswaty , Fitriani Rini , Galib M. 
Published: August 2023

Latar belakang: Preeklamsia masih menjadi tiga besar penyebab kematian ibu dalam bidang obstetri. Preeklamsia menduduki peringkat dua sebagai penyebab kematian langsung pada ibu hamil dan mengalami peningkatan setiap tahunnya. Kecemasan merupakan unsur kejiwaan yang menggambarkan perasaan, keadaan emosional yang dimiliki oleh seseorang pada saat menghadapi kenyataan atau kejadian dalam hidupnya. Hal ini meningkatkan eksresi hormon vasoaktif atau neuroendokrin lainnya yang dapat meningkatkan risiko hipertensi dan juga memicu perubahan pembuluh darah sehingga menyebabkan terjadinya preeklamsia.
Metode: Metode yang digunakan dalam penelitian ini yaitu analitik korelatif, dengan pendekatan cross sectional sebanyak 93 responden (1:2) yang dikumpulkan secara purposive sampling.
Hasil: Hasil uji statistik diperoleh P-value ≤ 0,05 dan PR = 4,646 (95% CI 1,824-7,288).
Kesimpulan: Pada penelitian ini terdapat hubungan yang signifikan antara kecemasan dengan kejadian preeklamsia di Rumah Sakit Khusus Daerah Ibu dan Anak Pertiwi Makassar.
Tatalaksana Syok Sepsis Akibat Community Acquired Pneumonia dengan Penyulit Acute Kidney Injury
Authors: Bachrun Tamsil , Muchtar Faisal , Salam Syamsul Hilal , Palinrungi Ari Santri 
Published: August 2023

Latar Belakang: Sepsis merupakan disfungsi organ yang mengancam jiwa akibat disregulasi respons tubuh terhadap infeksi. Pneumonia merupakan penyebab utama lebih dari 50% angka kejadian sepsis pada pasien di Intensive Care Unit (ICU).
Isi: Laporan kasus ini membahas pasien laki-laki usia 36 tahun dengan penurunan kesadaran dan gelisah, sesak napas disertai tidak ada produksi urin sejak 1 hari sebelumnya. Dari pemeriksaan fisis, laboratorium dan pemeriksaan penunjang pasien didiagnosis dengan syok sepsis yang disebabkan penumonia komunitas, edema paru karena paru uremik dan cedera ginjal akut pada penyakit ginjal kronik akibat nefropati diabetik.Pada pasien dilakukan pemberian ventilasi mekanik, vasopressor, pemasangan monitor invasif, sedasi dan analgetik, antibiotik empirik spektrum luas dan dilakukan continuous renal replacement therapy (CRRT) selama 4 hari.
Kesimpulan: Telah dilaporkan sebuah kasus keberhasilan dan keamanan penerapan CRRT pada pasien pneumoni komunitas dengan penyulit syok sepsis dan cedera ginjal akut di ICU. Terapi ini dapat dipertimbangkan sebagai salah satu pilihan pada pasien dengan masalah yang sama.
Penatalaksanaan Drowning: Review Article
Authors: Rusydi Muhammad Ammar , Farehan A Anggia Viona , Ashlihan Baiq Rulia , Olivia Fadila , Febrian Haldy Dwi 
Published: August 2023

Latar belakang: Drowning atau tenggelam didefinisikan sebagai masuknya cairan yang cukup banyak ke dalam saluran nafas atau paru-paru. Dalam kasus tenggelam, terendamnya seluruh tubuh dalam cairan tidak diperlukan. Yang diperlukan adalah adanya cukup cairan yang menutupi lubang hidung dan mulut sehingga kasus tenggelam tidak hanya terbatas pada perairan yang dalam seperti laut, sungai, danau, atau kolam renang, tetapi mungkin pula terbenam dalam kubangan atau selokan di mana hanya bagian muka yang berada di bawah permukaan air.
Isi: Ketika seseorang tenggelam, air yang masuk ke mulut bisa saja tertelan atau dimuntahkan. Ketika dorongan inspirasi terlalu tinggi untuk dilawan, air dapat tertelan ke saluran udara dan batuk terjadi sebagai respons refleks. Cairan yang diaspirasi dapat menyebabkan washout dan disfungsi surfaktan, peningkatan permeabilitas kapiler, kolaps alveolar, dan ketidaksesuaian rasio ventilasi- perfusi. Hal ini dapat menyebabkan keluhan pernapasan ringan hingga hingga edema paru non- kardiogenik fulminan, dengan gambaran klinis yang mirip dengan sindrom gangguan pernapasan akut atau dewasa (ARDS).
Kesimpulan: Near drowning atau keadaan hampir tenggelam merupakan suatu kondisi seseorang hampir mati karena tidak bisa bernapas atau tercekik di bawah air. Prinsip utama penatalaksanaan dalam kasus drowning adalah mempertahankan oksigenasi yang adekuat, mencegah aspirasi dari lambung, dan menstabilkan suhu tubuh. Berdasarkan hal ini, tatalaksana kegawatdaruratan yang dapat dilakukan yaitu berupa resusitasi jantung paru (RJP). Manajemen jalan napas yang baik menjadi aspek kunci dalam mendapatkan prognosis yang baik. Pasien near-drowning yang mengalami hipotermia ditatalaksana dengan prinsip rewarming baik aktif mau pun pasif.
Analisis Penggunaan Antibiotik Pasien Demam Tifoid dengan Komplikasi dan Tanpa Komplikasi yang Dirawat di Rumah Sakit
Authors: Idrus Hasta Handayani , Utami Nurfika , Rahmawati Rahmawati , Daeng Kanang Indah Lestari , Musa Inna Mutmainnah , Rasfayanah Rasfayanah 
Published: August 2023

Latar belakang: Demam tifoid disebabkan oleh bakteri Salmonella enterica reservoir typhi, juga dikenal sebagai salmonella typhi (S. typhi). Tujuan dari penelitian ini untuk mengetahui bagaimana efek penggunaan antibiotik pada pasien demam tifoid yang komplikasi dan tanpa komplikasi.
Metode: Jenis Penelitian ini adalah deskriptif kualitatif, menggunakan pendekatan Cross Sectional Study. Desain Cross Sectional Study digunakan karena proses pengambilan data dilakukan dengan menggunakan data yang telah ada sebelumnya di RSUD I Lagaligo Luwu Timur pada tahun 2021. Kriteria inklusi semua pasien yang terdiagnosis demam tifoid dengan dan tanpa komplikasi dengan analisis data menggunakan SPSS.
Hasil: Karakteristik penderita demam tifoid dengan komplikasi dan tanpa komplikasi berdasarkan terapi perawatan, diperoleh terapi perawatan paling banyak menggunakan ceftriaxon pada penderita dengan komplikasi sebanyak 21 orang (26,3%) dan tanpa komplikasi 22 orang (27,5%).
Kesimpulan: Terapi kausatif yang paling banyak digunakan pada penderita demam tifoid adalah penggunaan antibiotik golongan sefalosporin yaitu ceftriaxone dengan lama perawatan 1-14 hari.
Karakteristik Pasien Sirosis Hepatis
Authors: Amalia Mutiara , Hidayati Prema Hapsari , Eka Yanti Andi Kartini , Vitayani Sri , Gayatri Sri Wahyuni 
Published: August 2023

Latar belakang:. Berdasarkan data dari World Health Organization (WHO) pada tahun 2016 sekitar 51,1% laki laki dan 27,1% perempuan dari 100.000 populasi meninggal akibat sirosis hepatis. Di Indonesia data mengenai sirosis hepatis masih kurang oleh karena itu diperlukan penelitian mengenai karakteristik sirosis hepatis. Tujuan : Penelitian ini bertujuan untuk mengetahui karakteristik pasien sirosis hepatis di Rumah Sakit Ibnu Sina Makassar Tahun 2018-2021.
Metode: Desain penelitian yang digunakan yaitu deksriptif observasional. dengan menggunakan data sekunder dari rekam medik pasien sirosis hepatis di Rumah Sakit Ibnu Sina Makassar tahun 2018-2021. Hasil: Pada penelitian ini didapatkan usia terbanyak pada kelompok 51-60 tahun (45,5%) dan sebanyak 36 pasien (65,5%) berjenis kelamin laki laki. Dengan tingkat Pendidikan terakhir setara SMP/Sederajat (36,4%), dan berstatus tidak bekerja (41,8%). Penyebab sirosis terbanyak adalah hepatitis B (54,5%), dengan komplikasi terbanyak adalah asites (38,2%). Sekitar 29 pasien (52,7%) memiliki klasifikasi child pugh B dan sebagian besar sirosis hepatis dekompensata (46%).
Kesimpulan:. Pasien sirosis hepatis di RS. Ibnu Sina Makassar paling banyak ditemukan pada kelompok usia 51-60 tahun, laki laki, pendidikan terakhir SMP/Sederajat, dan tidak bekerja. Penyebab tersering hepatitis B dengan komplikasi asites, klasifikasi child pugh B, dan merupakan sirosis hepatis dekompensata.
The Development of Critical Thinking Skills Assessment Instrument Based on Nearpod in Junior High School Science Learning
Authors: Maghfiroh Rohmatul , Wahyuni Sri , Ridlo Zainur Rasyid 
Published: August 2023

Critical thinking skills are one of the skills needed in the 21st century, where to be able to assess critical thinking skills, assessment instruments are required. The aim of the research is development critical thinking skills instrument based on nearpod in junior high school science learning that meets valid, reliable, difficult, and practical criteria as well as critical thinking skills analysis. This research is a Research and Development research (R&D) with the GLAI model. The validity of the product is assessed by three validators consisting of one lecturer and two science teachers. Testing of assessment instruments was carried out on 125 grade VII students. The average product validity assessment of the three validators was 81.70% with valid criteria. Based on the field tests conducted, it is known that 10 items are valid with a reliability score of 0.602. At the difficulty level, the product has 1 easy item, 8 sufficient items, and 1 difficult item. In practicality, 97.66% was obtained with very practical criteria. In the analysis of critical thinking skills, the results of interpretation were obtained by 28.68% (very low), analysis by 31.20% (very low), inference by 43.44% (very low), and explanation by 47.80 % (low). So it is known that the critical thinking skills instrument based on nearpod in junior high school science learning was developed was valid, reliable, difficult levels, practical, and effective in measuring critical thinking skills.
The Effectiveness of Settlement of Criminal Acts of Minors Through Non-Litigation Efforts at the Gorontalo District Court
Authors: Amiri Ismiaty 
Published: August 2023

Abstract: This Reaserch aims at finding out (1) to what extent the efficacy of non-litigation, especially diversion in settlement of crimes involving children, in Gorontalo district court and (2) factors hindering the non-litigation process against crimes involving children in Gorontalo district court. The research method employs a normative and ampirical approach.Finding indicate that the implementation of non-litigation in settlement of crimes involving children in Gorontalo district court is less effective. This is due to the externalities existing on the child who is referred to as a perpetrator or victim’s parent/guardian. Hence, a thorough education outreach needs to be conducted to the family and the children regarding the objectives and the benefits of the diversion. Key words : Crimes Involving children, Non-Litigation, Diversion
Effectiveness of Impeachment Against Deputy Regent of Gorontalo Regency
Authors: Lasimpala Luksiana , W. Badu Lisnawaty , M. Nggilu Novendri 
Published: August 2023

The purpose of this research is to know and analyze the Legal Regulation of The Impeachment of Regional Heads and/or Deputy Heads of Regions according to The Provisions of Law No. 23 of 2014 on Local Government and the effectiveness of impeachment against the deputy Regent of Gorontalo Regency. The type of research used by researchers in the preparation of this study is to use normative research types that are supported by the existence of field data (empirical) using 2 (two) approaches, namely the Legislative And Case Approach. The results of this study show that the effectiveness of impeachment against the deputy Regent of the Gorontalo Regency is influenced by 3 (three)factors that affect the effectiveness of dismissal against the deputy Regent of the Gorontalo Regency, namely: the legal factor. alone, where there is no normative framework that regulates the law of dismissal events in the head of the region, second, law enforcement factors, namely regarding the competence of judges in the break the case and the unclear involvement of legal counsel (advocate), third, the legal culture factor characterized by the disobedience of the Ministry of Home Affairs to the deadline which has been made imitatively in Law 23 of 2014 concerning Local Government.
Analysis Of The Role Of Traffic Units Against Offenders Of Speed Limit Violations That Cause Accidents
Authors: Pasambuna Ari Yoga 
Published: August 2023

This study aims to find out how the analysis of the role of traffic units against criminal offenders of vehicle speed limit violations that cause accidents in Kotamobagu and what are the obstacles faced in minimizing traffic accidents due to speed limit violations in Kotamobagu and using this type of empirical legal research using qualitative approaches. This method of empirical legal research serves to see the law in reality in the community by collecting data and results with sources. The results of the research obtained the role of the Kotamobagu Resort Police Unit, namely preventive efforts (prevention) in the form of socialization and education to the community of road users and traffic engineering and repressive efforts (enforcement) in the form of Arrangements, Guarding, Escorts, and Patrols and enforcement against perpetrators of traffic accidents. Then the obstacles faced are the lack of facilities and infrastructure and lack of legal awareness in the community. Keywords: Satlantas; Speed Limit; Accident.
The Importance Of Protecting The Personal Data Of Social Media Users In The Era Of Digitalization
Authors: Katili Mohammad Gufran 
Published: August 2023

Abstract: Technology that moves forward and develops over time makes various kinds of changes happening around us. Social media was born as a form of technological sophistication itself that brings convenience to its users. This study uses normative methods by analyzing forms of legal protection in the context of personal data contained in several related laws. It is hoped that this article can be a characteristic of the knowledge of its readers in building a common awareness of the importance of protecting each other's data from crimes that may lurk. The results obtained through this study through various existing laws related to the form of personal data protection itself are not spelled out explicitly, causing legal blurring that leads to less effective enforcement of existing laws as a form of personal data protection.Keywords: Technology; Personal data; Social media.
Criminal Act of Destruction of Campaign Props of Candidates for dark election 2019 Gorontalo province
Authors: Perdana Tangahu Mohamad Rama 
Published: August 2023

Abstract: This study aims to find out what factors are behind the perpetrators of the destruction of campaign props belonging to the Dprd Candidate in the 2019 General Election in The Gorontalo Province General Election Supervisory Agency and to find out how law enforcement efforts against criminals damage the campaign props of the DPRD Candidate in the 2019 General Election are reviewed from Law No. 7 of 2017 concerning general elections. The results of this study show: First,law enforcement efforts carried out by The Election Supervisory Agency together with gakumdu in handling election crimes against perpetrators of APK destruction in accordance with the applicable regulations as the provisions of Article 486 of Law No. 7 of 2017 concerning General Elections, Election Supervisory Agency Gorontalo Province and Regency / City in handling findings / reports of alleged election crimes including destruction of APK then enforcement The law is carried out jointly with the police and prosecutors through the Integrated Law Enforcement Center (Sentra Gakkumdu); Second,the factors behind the perpetrators doing damage to campaign props belonging to the DPRD Candidate in the 2019 General Election are (1) Weak awareness and knowledge of election law; (2) The existence of fanatical and anti-presidential behavior against certain Candidates / Election Participants; (3) The influence of liquor so that the perpetrators do damage to campaign props (billboards) belonging to one of the legislative candidates. Keywords: Destruction, APK, Legislative Member, Elections
Legal Consequences of Betel Marriage Settlement During the Covid-19 Pandemic
Authors: Dama Nadia Dhea Safira , Harun Amanda Adelina 
Published: August 2023

This study aims to determine the legal consequences of betel marriage settlement during the Covid-19 pandemic. The type of research used is sociological juridical and this study uses a descriptive research approach and qualitative data analysis techniques. The results of this study show that the legal consequences of an unrecorded marriage can cause the marriage to be invalid in the eyes of positive Indonesian law, but according to religion and public belief that the marriage is valid as long as it meets the conditions and legal pillars of a marriage itself. As for the settlement, there are two things, namely the application for a marriage and remarriage hearing. However, the bad factor is that if the marriage partner has obtained a child, then in civil law the child does not have a nasab with the father but only has a nasab with a mother and her family.
Children as Perpetrators of Crimes of Abuse (A Review of Restorative Justice Completion in Indonesia)
Authors: Alhasni Moh Husen 
Published: August 2023

This research aims to explain the phenomenon of children as perpetrators of violent crimes and examine the restorative resolution approach in Indonesia. In recent years, there has been an increase in the number of cases of violence involving children as perpetrators in Indonesia. The existence of children as perpetrators of violent crimes raises serious concerns about the future of the younger generation and the security of society. The research method used in this writing is Juridical Sociological research and uses a qualitative research approach that is descriptive in nature and uses interactive analysis techniques. the research findings show that the restorative resolution approach has been recognized as a more effective alternative and focuses on victim recovery, offender development, and social reintegration. Restorative resolution involves a process of mediation and dialogue between the victim, offender and the community. The results show that this approach provides space for juvenile offenders to understand and take responsibility for their actions, while victims can express the psychological and emotional impact they have experienced.
Bradykinesia and dystonia
Authors: Paparella Giulia , Guerra Andrea , Galosi Serena , Cannavacciuolo Antonio , Angelini Luca , Popa Traian , Berardelli Alfredo , Bologna Matteo 
Published: August 2023

Background: Bradykinesia has been reported in patients with dystonia. Despite this, the pathophysiological mechanisms of bradykinesia in dystonia remain largely unknown.Methods: We here performed a comprehensive literature search and reviewed clinical and experimental studies on bradykinesia in patients with dystonia.Results: Many studies have documented the presence of bradykinesia in patients with idiopathic and inherited isolated dystonia, regardless of the presence of parkinsonism. In addition, bradykinesia has been observed as a side effect in dystonic patients who have undergone deep brain stimulation, in those with functional dystonia as well as in those with combined dystonia, e.g., dystonia-parkinsonism. These clinical and experimental findings support the hypothesis that dysfunction in a brain network involving the basal ganglia, primary sensorimotor cortex, and cerebellum may play a key role in the pathophysiology of both bradykinesia and dystonia.Conclusion: Bradykinesia is frequently observed in dystonia. We may gain insights into the pathophysiological underpinnings of two distinct movement disorders by investigating this issue. Furthermore, a deeper understanding of bradykinesia in dystonia may have terminological implications in this field.
Impact of an inquiry-oriented proposal for promoting technology-enhanced learning in a post-pandemic context
Authors: Campillo-Ferrer José-María , Miralles-Martínez Pedro 
Published: August 2023

IntroductionThis study examines the effectiveness of learning processes developed through a technology-enhanced approach in higher education. Therefore, we analyzed Webquests together with other gamification resources, considered relevant research studies on the impact and advantages of this inquiry-oriented learning approach, and examined students’ perceptions of the effects of these online learning tools on developing their organizational skills and effective planning for learning.MethodsParticipants in the study were 73 student teachers enrolled in the core unit of Social Studies, in the second year of the Primary Education degree at the University of Murcia (Spain). In this study, a pre-test and posttest design was applied and questionnaires were administered to students at the beginning and end of the term to examine the impact of this inquiry-oriented approach on the development of students’ learning processes. Their perceptions of the learning achieved were analyzed using statistical software for Excel (XLSTAT).ResultsThe results indicate that these online tools effectively promote technology-enhanced learning and collaborative work, especially among the most motivated and digitally literate students, underlining the importance of motivation and digital literacy as catalysts for learning.DiscussionThe study also highlights the need for further research on the impact of digital resources in promoting competency-based learning alongside other motivational online approaches in tertiary education.
Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease
Authors: Mitchell Nadia L. , Murray Samantha J. , Wellby Martin P. , Barrell Graham K. , Russell Katharina N. , Deane Ashley R. , Wynyard John R. , Palmer Madeleine J. , Pulickan Anila , Prendergast Phillipa M. , Casy Widler , Gray Steven J. , Palmer David N. 
Published: August 2023

CLN5 neuronal ceroid lipofuscinosis (NCL, Batten disease) is a rare, inherited fatal neurodegenerative disorder caused by mutations in theCLN5gene. The disease is characterised by progressive neuronal loss, blindness, and premature death. There is no cure. This study evaluated the efficacy of intracerebroventricular (ICV) delivery of an adeno-associated viral vector encoding ovineCLN5(scAAV9/oCLN5) in a naturally occurring sheep model of CLN5 disease. CLN5 affected (CLN5−/−) sheep received low, moderate, or high doses of scAAV9/oCLN5 at three disease stages. The treatment delayed disease progression, extended survival and slowed stereotypical brain atrophy in most animals. Of note, one high dose treated animal only developed mild disease symptomology and survived to 60.1 months of age, triple the natural life expectancy of an untreated CLN5−/−sheep. Eyesight was not preserved at any administration age or dosage. Histopathologic examination revealed that greater transduction efficiency was achieved through higher ICV doses, and this resulted in greater amelioration of disease pathology. Together with other pre-clinical data from CLN5−/−sheep, the safety and efficacy data from these investigational new drug (IND)-enabling studies supported the initiation of the first in-human CLN5 gene therapy clinical study using the ICV delivery route for the treatment of CLN5 NCL.Clinical Trial Registration:https://clinicaltrials.gov/, identifier NCT05228145