bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two sides of the same wing: ventral scales enhance dorsal wing color in the butterfly Speyeria mormonia
Authors: Chappell Daniel R. , Boggs Carol L. , Speiser Daniel I. 
Published: September 2023

ABSTRACT
Biological visual signals are often produced by complex interactions between light-absorbing and light-scattering structures, but for many signals, potential interactions between different light-interacting components have yet to be tested. Butterfly wings, for example, are thin enough that their two sides may not be optically isolated. We tested whether ventral wing scales of the Mormon fritillary, Speyeria mormonia, affect the appearance of dorsal orange patches, which are thought to be involved in sexual signaling. Using reflectance spectroscopy, we found that ventral scales, either silvered or non-silvered, make dorsal orange patches significantly brighter, with the silvered scales having the greater effect. Computational modeling indicates that both types of ventral scale enhance the chromatic perceptual signal of dorsal orange patches, with only the silvered scales also enhancing their achromatic perceptual signal. A lack of optical independence between the two sides of the wings of S. mormonia implies that the wing surfaces of butterflies have intertwined signaling functions and evolutionary histories.
Heterogeneity and Adjuvant Therapeutic Approaches in MSI-H/dMMR Resectable Gastric Cancer: Emerging Trends in Immunotherapy
Authors: Wu Hui , Ma Wenyuan , Jiang Congfa , Li Ning , Xu Xin , Ding Yongfeng , Jiang Haiping 
Published: September 2023

AbstractGastric cancer (GC) remains one of the world’s most common and fatal malignant tumors. With a refined understanding of molecular typing in recent years, microsatellite instability (MSI) has become a major molecular typing approach for gastric cancer. MSI is well recognized for its important role during the immunotherapy of advanced GC. However, its value remains unclear in resectable gastric cancer. The reported incidence of microsatellite instability-high (MSI-H)/deficient mismatch repair (dMMR) in resectable gastric cancer varies widely, with no consensus reached on the value of postoperative adjuvant therapy in patients with MSI-H/dMMR resectable GC. It has been established that MSI-H/dMMR tumor cells can elicit an endogenous immune antitumor response and ubiquitously express immune checkpoint ligands such as PD-1 or PD-L1. On the basis of these considerations, MSI-H/dMMR resectable GCs are responsive to adjuvant immunotherapy, although limited research has hitherto been conducted. In this review, we comprehensively describe the differences in geographic distribution and pathological stages in patients with MSI-H/dMMR with resectable gastric cancer and explore the value of adjuvant chemotherapy and immunotherapy on MSI-H/dMMR to provide a foothold for the individualized treatment of this patient population.
Reproducibility and location-stability of radiomic features derived from cone-beam computed tomography: a phantom study
Authors: He Xian , Chen Zhi , Gao Yutao , Wang Wanjing , You Meng 
Published: September 2023

Objectives:
This study aims to determine the reproducibility and location-stability of cone-beam computed tomography (CBCT) radiomic features.

Methods:
Centrifugal tubes with six concentrations of K2HPO4 solutions (50, 100, 200, 400, 600, and 800 mg ml−1) were imaged within a customized phantom. For each concentration, images were captured twice as test and retest sets. Totally, 69 radiomic features were extracted by LIFEx. The reproducibility was assessed between the test and retest sets. We used the concordance correlation coefficient (CCC) to screen qualified features and then compared the differences in the numbers of them under 24 series (four locations groups * six concentrations). The location-stability was assessed using the Kruskal-Wallis test under different concentration sets; likewise, the numbers of qualified features under six test sets were analyzed.

Results:
There were 20 and 23 qualified features in the reproducibility and location-stability experiments, respectively. In the reproducibility experiment, the performance of the peripheral groups and high-concentration sets was significantly better than the center groups and low-concentration sets. The effect of concentration on the location-stability of features was not monotonic, and the number of qualified features in the low-concentration sets was greater than that in the high-concentration sets. No features were qualified in both experiments.

Conclusions:
The density and location of the target object can affect the number of reproducible radiomic features, and its density can also affect the number of location-stable radiomic features. The problem of feature reliability should be treated cautiously in radiomic research on CBCT.
An effective solution to boost generation from waves: Benefits of a hybrid energy storage system integration to wave energy converter in grid-connected systems
Authors: Barelli Linda , Bidini Gianni , Ciupageanu Dana Alexandra , Ottaviano Andrea , Pelosi Dario , Gallorini Federico , Alessandri Giacomo , Atcheson Cruz Mairead 
Published: September 2023

Background: Wave energy represents one of the most promising renewable energies due to its great theoretical potential. Nevertheless, the electrical compliance of grid-connected systems is a great issue nowadays, due to the highly stochastic nature of wave energy. Methods: In this paper, a Hybrid Energy Storage System (HESS) consisting of a Li-ion battery and a flywheel is coupled to a Wave Energy Converter (WEC) that operates in grid connected mode. The study is performed using real yearly wave power profiles relating to three different sites located along the European coasts. The Simultaneous Perturbation Stochastic Approximation (SPSA) principle is implemented as real-time power management strategy for HESS in wave energy conversion systems. Results: Obtained results demonstrate how the proposed HESS and the implementation of the SPSA power management coupled to a WEC allow a reduction of more than 80% of power oscillations at the Point of Common Coupling (PCC), while proving the robustness of the developed management strategy over the investigated sites. Moreover, the average energy penalty due to the HESS integration results slightly higher than 5% and battery solicitation is reduced by more than 64% with respect to the flywheel solicitation, contributing to extend its lifetime. Conclusions: HESS integration in renewable generation systems maximizes the WEC production while smoothing the power at the PCC. Specifically, flywheel-battery HESS together with the implemented power management strategy could provide a great flexibility in the view of increasing power production from waves, strongly mitigating the variability of this source while enhancing grid safety and stability.
On binary opposition and binarism: A long-distance dialogue between decolonial critique and the Lotmanian semiotics
Authors: Gherlone Laura 
Published: September 2023

While addressing the decolonial critique of Eurocentric modernity and the call for alternative cosmo-visions, this article retraces Juri Lotman’s culturological exploration towards the concept of ternarity [тернарность]: the scrutiny of the so-called binarism is what connects – without overlapping – the two perspectives.
This long-distance dialogue will be built starting with the key notion of binary opposition, which will be analysed as a decolonial problem (Part I) and as a culturological problem (Part II). The analysis will focus on two central issues that stem from the either-or logic: the “othering mindset”, and the culture–nature dualism.
Resource-Window Reduction by Reduced Costs in Path-Based Formulations for Routing and Scheduling Problems
Authors: Bianchessi Nicola , Gschwind Timo , Irnich Stefan 
Published: September 2023

Many routing and scheduling problems are modeled through variables that represent paths (routes, schedules, etc.). For such extensive formulations, branch-price-and-cut (BPC) algorithms nowadays constitute the leading exact solution technique, and most of the time, the pricing problem is a shortest-path problem with resource constraints that can be solved by a dynamic-programming labeling algorithm. For this setting, variable fixing techniques based on the reduced costs of the paths have been proposed with the aim of eliminating arcs from the underlying network and speeding up the solution process of the pricing problem as well as of the overall BPC algorithm. For an efficient variable fixation, bidirectional labeling must be possible. We move one step forward and show how the reduced costs of paths can also be exploited to reduce the resource windows for many types of resources, including the time resource and a load-related resource. This can be achieved without modifying the pricing problem network and altering the structure of the pricing problem itself. Moreover, different resources can be considered simultaneously. A straightforward reduction of the resource windows associated with the vertices of the network can tighten them, but this reduction does not translate into savings in computation times. On the contrary, the reduction of the resource windows is effective when distinct forward and backward resource windows are defined for each arc and reduced independently based on the traversal direction of the arc itself. Moreover, an arc can be eliminated when one of its arc-specific resource windows becomes empty, and the explicit use of variable fixing techniques can be avoided. Computational results obtained for benchmark instances of the vehicle-routing problem with time windows show that the overall computation times of the BPC algorithm can be significantly reduced compared with a fully fledged BPC algorithm using variable fixing techniques. History: Accepted by Andrea Lodi, Area Editor for Design & Analysis of Algorithms – Discrete. Funding: This research was supported by the Deutsche Forschungsgemeinschaft (DFG) [Grants GS 83/1-1 and IR 122/10-1] of Project 418727865. This support is gratefully acknowledged.
Constituição psíquica infantil e o brincar mediado: estudo a partir da teoria histórico-cultural
Authors: Lumertz Fábia Daniela Schneider , Oliveira-Menegotto Lisiane Machado de Oliveira 
Published: September 2023

O artigo tem como tema central o brincar e o papel da mediação nesse processo, tendo como objetivo principal refletir sobre a mediação do brincar no processo de constituição psíquica infantil desde o início da vida, quando o brincar é marcado fortemente pela intervenção de um outro humano que nomeia os objetos e aponta as suas funções para a criança, até o brincar simbólico, fruto da ação da imaginação sobre os objetos e sobre as situações sociais da vida. Trata-se de um estudo teórico, de revisão narrativa da literatura, feito com pesquisa bibliográfica qualitativa fundamentada na base conceitual da teoria histórico-cultural do desenvolvimento psíquico humano. O estudo destaca o brincar mediado como fundamental para o desenvolvimento das funções psicológicas superiores e para a humanização infantil. Assim, este trabalho pode contribuir para o entendimento da aprendizagem mediada desde o início da vida e da imprescindibilidade do brincar no desenvolvimento psíquico infantil.
“I’m Home”: “Russian” Houses in Germany and Their Objects
Authors: Buchatskaya Julia 
Published: September 2023

Abstract
In this article, I will focus on the study of the living space in houses of Russian-speaking emigrants in 1990s–2000s in Germany. I will discuss the “home” in several aspects: in a wide sense as a place on Earth where people’s life goes on, as physically built environment where a family dwells, and as objectified everyday life in the interiors. The choice of objects and furnishings for a “Russian” house in Germany cannot be classified, but it is unique and is associated with the biographies of the owners, the history of each individual family, as well as the history of moving to Germany. The “Russian” house in Germany turns out to be a complex phenomenon: it can be seen as a safe space, escape from the outside world, and offering emotional comfort. It is a place for representation of family and personal values, the owners’ identity, and preferences. It is also a scene where scenarios of relationships between a person and objects unfold. The objects that a person places in his/her house appear as objectified memories of life events and other people, reflecting the importance of family and interpersonal relationships expressed in gifts, photos, children’s drawings, and crafts. In a new place, people are no longer limited to a set of typical furnishing patterns that were dictated by a shortage of goods and ideas in the country of origin. House owners show their personality, trying to make their home different from that in the place of origin and introduce a non-standard style of European interiors in their homes, yet unwittingly they often reproduce stereotypes and fragments from their previous houses where they lived before migrating.
The crystal structure of catena-poly[aqua-(4-iodopyridine-2,6-dicarboxylato-κ
3
N,O,O
′)-copper(II)] monohydrate, C7H6NO6ICu
Authors: Kong Yang , Lu ChenFei , Wang Chang-Zhao , Tian Bin , Dang YiXuan , Han ZiHao 
Published: September 2023

Abstract
C7H6NO6ICu, monoclinic, P21/n (no. 14), a = 9.7229(4) Å, b = 5.1728(2) Å, c = 20.8336(8) Å, β = 97.636(4)∘, V = 1038.52(7) Å3, Z = 4, R

gt
(F) = 0.0287, wR

ref
(F
2) = 0.0687, T = 293 K.
Synthesis and crystal structure of 2-(3-oxo-3-phenylpropyl)isoindoline-1,3-dione, C17H13NO3
Authors: Shi Ju-Mei , Hao Yong-Jia , Xu Lian-Hua , Zhou Ying , Wang Hua-Bin 
Published: September 2023

Abstract
C17H13NO3, monoclinic, P21/c (no. 14), a = 9.5306(2) Å, b = 6.1971(2) Å, c = 23.3849(7) Å, β = 101.445(3)°, V = 1353.70(7) Å3, Z = 4, Rgt
(F) = 0.0644, wR

ref
(F
2) = 0.1909, T = 120 K.
Crystal structure of 6,6a,7,8,9,10-hexahydro-5H-pyrazino [2,3-e]pyrido[1,2-a]pyrazine, C10H14N4
Authors: Dali Zhu , Yu Yu 
Published: September 2023

Abstract
C10H14N4, orthorhombic, Pbca (no. 61), a = 15.5356(2) Å, b = 9.8551(2) Å, c = 25.5551(4) Å, V = 3912.61(11) Å3, Z = 16, R

gt
(F) = 0.0873, wR

ref
(F
2) = 0.2481, T = 150 K.
The influence of creases on carton board package behavior during point loading
Authors: Persson Camilla , Eriksson Henry , Korin Christer 
Published: September 2023

Abstract
Carton board packages with different creases have been manufactured and loaded with point loads to see if there is a difference in point load behavior depending on crease. A carton board was creased in four different ways. The differences of the creases were judged according to appearance and residual moment. Three of the four creases showed divergent appearances. The residual moment was as expected lowest for the hardest creased sample and vice versa. The packages with the different creases were loaded with a point load. The registered force – displacement curves were analyzed according to stiffness and collapse load. No statistically significant difference could be seen in the collapse load of the package or in the stiffness measured, indicating that with a standard point load measurement it was hard to distinguish a difference in packaging behavior due to creasing. In future work it might be interesting to further study the average stiffness, since a trend of higher average stiffness for lower matrix channel depth exists in the measurements, however not statistically ensured. One possibility to discern possibly existing differences in the resistance of packaging to point load due to crease differences could be to study the interaction in more detail.
Antibody biopolymer conjugate
Authors: Chavda Vivek P. , Balar Pankti C. , Patel Srushti B. , Bhavsar Diya J. , Lakhani Margi V. , Parmar Resa 
Published: September 2023

Abstract
Antibody treatment is an emerging field of treatment. They activate the immune system and help us fight foreign matter. Antibody biopolymer conjugates (ABC) is the futuristic preparation for successfully dealing with all the drawbacks of the unconjugated naked antibodies and improving the therapeutic effect. This chapter will state detailed information from the basics about its structure, its binding, and its mechanism of action. KSI-301 is one of the most researched and important molecules of ABC that is under many clinical trials. It helps to increase patient compliance by decreasing the frequent administration of a drug and hence improving the quality of life. The chapter also includes its current application and future aspects to fascinate the reader.
Flywheel Eccentric Training: How to Effectively Generate Eccentric Overload
Authors: Martínez-Hernández David 
Published: September 2023

ABSTRACT
Eccentric resistance training has been shown to elicit beneficial effects on performance and injury prevention in sports because of its specific muscular and neural adaptations. Within the different methods used to generate eccentric overload, flywheel eccentric training has gained interest in recent years because of its advantages over other methods such as its portability, the ample exercise variety it allows and its accommodated resistance. Only a limited number of studies that use flywheel devices provide enough evidence to support the presence of eccentric overload. There is limited guidance on the practical implementation of flywheel eccentric training in the current literature. In this article, we provide literature to support the use of flywheel eccentric training and present practical guidelines to develop exercises that allow eccentric overload.
See Supplemental Digital Content 1, http://links.lww.com/SCJ/A380 for a video abstract of this article.
A mitochondrial EglN1‐AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress
Authors: Jiang Weiwei , Zhang Mengyao , Gao Chuan , Yan Chaojun , Gao Ronghui , He Ziwei , Wei Xin , Xiong Jingjing , Ruan Zilun , Yang Qian , Li Jinpeng , Li Qifang , Zhong Ziyi , Zhang Mengna , Yuan Qianqian , Hu Hankun , Wang Shuang , Hu Ming‐Ming , Cai Cheguo , Wu Gao‐Song , Jiang Chao , Zhang Ya‐Lin , Zhang Chen‐Song , Zhang Jing 
Published: September 2023

AbstractMitochondria play essential roles in cancer cell adaptation to hypoxia, but the underlying mechanisms remain elusive. Through mitochondrial proteomic profiling, we here find that the prolyl hydroxylase EglN1 (PHD2) accumulates on mitochondria under hypoxia. EglN1 substrate‐binding region in the β2β3 loop is responsible for its mitochondrial translocation and contributes to breast tumor growth. Furthermore, we identify AMP‐activated protein kinase alpha (AMPKα) as an EglN1 substrate on mitochondria. The EglN1‐AMPKα interaction is essential for their mutual mitochondrial translocation. After EglN1 prolyl‐hydroxylates AMPKα under normoxia, they rapidly dissociate following prolyl‐hydroxylation, leading to their immediate release from mitochondria. In contrast, hypoxia results in constant EglN1‐AMPKα interaction and their accumulation on mitochondria, leading to the formation of a Ca2+/calmodulin‐dependent protein kinase 2 (CaMKK2)‐EglN1‐AMPKα complex to activate AMPKα phosphorylation, ensuring metabolic homeostasis and breast tumor growth. Our findings identify EglN1 as an oxygen‐sensitive metabolic checkpoint signaling hypoxic stress to mitochondria through its β2β3 loop region, suggesting a potential therapeutic target for breast cancer.
Testing simplification in translated and creative writing texts: The case of Robert van Gulik's Judge Dee detective stories
Authors: Chen Juqiang , Chang Hui 
Published: September 2023

AbstractTranslational language has been reported to have unique characteristics, or translation universals, as compared to native non-translational production. One of the most widely studied features is simplification, i.e., translated texts tend to be less complex than non-translational texts. This study tested this hypothesis by comparing the translated and creative writing texts produced by a single author, Robert van Gulik, on the same topic (Judge Dee's detective adventures). Our well-controlled comparisons showed that the translated text was lexically less diverse, but syntactically more complex and generally less readable. The cognitive load of translation and the source text constrained the amount of vocabulary used in the translation compared with free writings. On the other hand, longer and more complex sentences reflected the translator's efforts to state the information in a more explicit form when conveying the ancient Chinese detective stories to the Western world. Our research, thus, offers some insights into the investigation of the simplification hypothesis and the relation between translation and writing.
A dzsihádista merényletekben 2015 óta bekövetkezett változások Nyugat- és Észak-Európában
Authors: Szabó Zoltán 
Published: September 2023

Összefoglalás.

A tanulmány bemutatja, hogyan és miként változtak meg a nyugat- és észak-európai
dzsihádista terrortámadások végrehajtási módjai az elmúlt években, és
esettanulmányokon keresztül igyekszik rávilágítani az elkövetők általános
jellemzőire.

Summary.

This paper aims to show how terrorist attacks in Western and Northern Europe have
changed in recent years, especially in comparison to the attacks in Paris in
November 2015 and Brussels in March 2016. Case studies of successful attacks in
2021 and 2022 highlight the general characteristics of the perpetrators. Several
conclusions can be drawn through brief profiles of Ndiaga Dieye, Abdellah Gmara,
Jamel Gorchene, Ali Harbi Ali, Abdalrahman A., Emad al-Swealmeen, Franck Elong
Abé, Zaniar Matapour and Yassine Mahi.
On one hand, it can be established that these persons have either entered the
territory of the European Union as irregular immigrants or have committed
terrorist acts as second-generation nationals of their countries. It can also be
said that in recent years only lone perpetrators have been able to carry out
successful attacks, i.e. the above-mentioned persons have planned and carried
out their acts entirely on their own, with at most only tangential links to an
Islamist terrorist organisation.
The common feature of the perpetrators is that they are all young men, with an
average age of 33. They all had some form of mental disorder. Most of them have
chosen to use a stabbing weapon, but it can be seen that they may be seeking to
acquire firearms or to make explosives at home. They generally attacked “soft”
targets, i.e. civilians, as they were expected to put up much less resistance
than “hard” targets, i.e. police or soldiers. Nevertheless, it can be observed
that many of the terrorists presented also attacked police officers, which may
illustrate, among other things, a dislike of the authorities or a desire to see
such an act receive more press coverage.
At one point in their lives, the individuals profiled in this study were clearly
radicalised, i.e. they adopted and embraced opinions and views that ultimately
led them to commit an act of terrorism. While no clear pattern of radicalisation
can be drawn from the case studies, it is possible to identify a significant
role for both online and offline spaces. Some may have decided to turn to
extremist Islamism solely on the basis of online sources, but others may have
first encountered radical ideas in prison.
The role of time is also an important factor. The speed with which someone
becomes radicalised and the time it takes for them to commit a terrorist act (if
at all) is individual-specific.
Finally, it is important to note that the process of radicalisation can be
triggered or even accelerated by a perceived or real grievance against
Muslims.