bluuebunny/crossref_metadata_2025_split huggingface dataset:
КОХЛЕАРЛЫ ИМПЛАНТАЦИЯДАН КЕЙІН БАЛАЛАРДЫҢ ЕСТУ-СӨЙЛЕУ ҚАБІЛЕТІН ОҢАЛТУ ЖҰМЫСЫТӘЖІРИБЕСІНЕН
Authors: Yasinovskaya G.A. , IbragimovaY V. 
Published: April 2023

The article summarizes the practical experience of teachers in hearing and speech rehabilitation of children after cochlear implantation. The work is based on the "auditory method". Particular attention is paid to the specifics of working with children at the language stage. The article contains exercises that develop in children with CI the ability to recognize and understand words in continuous speech. The article is intended for parents of children with CI, deaf teachers, defectologists and studentsKeywords:cochlear implantation, rehabilitation, developpment of auditory perception, auditory method, language stade
Встатьеобобщается практический опыт педагогов по слухоречевой реабилитации детей после кохлеарной имплантации. Работа построена на основе «слухового метода». Особое внимание уделено специфике работы с детьми на языковом этапе. Статьясодержит упражнения, которые развивают у детей с КИ умение узнавать и понимать слова в слитной речи. Статья предназначена для родителей детей с КИ, сурдопедагогов, дефектологов и студентов.
Мақалада кохлеарлық имплантациядан кейінгі балалардың есту-сөйлеу реабилитациясы бойынша педагогтардың практикалық тәжірибесі жинақталған. Жұмыс «есту әдісі» негізінде жасалған. Жұмыс барысында ең өзекті назар тілдік кезеңге аударылған. Мақалада КИ бар балаларда тұтас сөйлеудегі сөздерді тану және түсіну қабілетін дамытатын жаттығулар бар. Мақала КИ бар балалардың ата-аналарына, сурдопедагогтарға, дефектологтарға және студенттерге арналған.
ПСИХИКАЛЫҚ ДАМУЫНДА ТЕЖЕЛУІ БАР БАЛАЛАРДЫҢ ЕРЕКШЕЛІКТЕРІ ЖӘНЕ ЛОГОПЕДИЯЛЫҚ ТҮЗЕТУ ЖОЛДАРЫ
Authors: Tusip K.E. 
Published: April 2023

The article examines on the theoretical principle the levels of general underdevelopment of speech of preschoolers with mental retardation, it is aimed at the productive organization of correctional work taking into account the peculiarities of children's speech. Correctional work is provided for the formation of phonemic perception and sound analysis in children.
В статье рассматриваетсяна теоретическом принципе уровни общего недоразвития речи дошкольников с задержкой психического развития, она направлена на продуктивную организацию коррекционной работы с учетом особенностей речи детей. Предусмотрена коррекционная работа по формированию у детей фонемактического восприятия и звукового анализа
Психикалық дамуында тежелуі бар мектепке дейінгі балалардың сөйлеу тілінің жалпы дамымау деңгейлерін теориялық қағидада қарастыра отыра, балалардың сөйлеу тіліндегі ерекшеліктерін ескеріп, түзету жұмыстарын нәтижеліұйымдастыруға бағытталған. Балалардың фонемактикалық қабылдауды және дыбыс анализін қалыптастыруына түзету жұмыстары қарастырылған.
Investigating the Factors That Influence Digital Transformation: A Systematic Literature Review
Authors: Alshammari Khalid 
Published: April 2023

The digital transformation is trending in the business world. All businesses are keen to have and pursue a digital transformation strategy. However, many organizations are not fully understood what digital transformation is, how it should be performed and what is the best for the organization. thus, this paper seeks to understand the factors that might impact the digital transformation in organizations. This systematic literature review considers the course of digital transformation in organizations
Art, Music, & Mashups: A View from the Bench on Creativity and Copyright
Authors: McKeown M. Margaret 
Published: April 2023

Creativity has captured human fascination for centuries. It has been said that “[t]here is little that shapes the human experience as profoundly and pervasively as creativity.” But what is creativity? Is it pure originality? Divine inspiration? Clever assimilation of existing ideas? Despite creativity’s central role in human progress, the term eludes finite definition.
To Plato, creative inspiration was divine. In contrast, Kant thought that creative geniuses were not divinely inspired but born with a particular quickness of mind that fostered brilliance and innovation. T.S. Eliot recognized the critical role of borrowing in creative work, quipping, “[i]mmature poets imitate; mature poets steal; bad poets deface what they take; and good poets make it into something better, or at least something different.”
In psychology, a leading theory of creativity requires inspiration from existing concepts. In his “associative theory” of creativity, Sarnoff Mednick posits that most of us have predictable, stereotypical associations with a given stimulus, while the creative among us are able to retrieve remote associations. For instance, although most associate “table” with “chair,” the creative might proffer “leg” or “food.” Defining creativity as a framework of novel associations between existing concepts, Mednick distinguishes originality from creativity, finding the former of little import.
However different theorists and disciplines might define creativity, its outcomes are varied, enduring, and ever evolving. Creativity has brought us everything from Rodin’s sculptures and Van Gogh’s paintings to Newton’s scientific discoveries, from musical scores and movies to computer code.
Where, then, does the law intersect with creativity? The United States Constitution directs Congress to “promote the Progress of Science and useful Arts, by securing for limited Times to Authors and Inventors the exclusive Right to their respective Writings and Discoveries.” Born from that critical clause is the American approach to copyright. Recognized by the U.S. Supreme Court as “the engine of free expression,” copyright law enriches “the general public through access to creative works.”
To illustrate how copyright law fulfills its aims through the lens of art, music, and “mashups,” I invite you to accompany me on a short tour of copyright law’s dance with creativity by offering select examples from federal appellate decisions and a view from the bench.
Foreign research experience of the effect of probiotic agent on the intestinal microbiome of poultry
Authors: Pimenov N. V. , Smirnova E. , Ivannikova R. F. 
Published: April 2023

The intensive development of industrial animal husbandry and poultry farming, along with the ban on the use of antibiotics for non-medicinal purposes, requires a revision of stimulating and therapeutic and preventive approaches aimed at increasing productivity, protecting against infections and improving other production parameters, such as feed digestibility and improving the efficiency of digestion, stimulating growth and development, the quality of meat, milk, eggs. In this regard, probiotic, prebiotic and synbiotic drugs and feed additives have become widespread. Funds based on antagonistic bacteria and representatives of symbiotic microflora are actively being introduced into poultry technology, a wide domestic research experience reveals their prospects. Used mainly to maintain the balance of the intestinal microbiota, they turn out to be an effective method of combating opportunistic pathogens.At the same time, in the countries of developed industrial poultry farming, products based on probiotic cultures have not been widely used, and a number of sources are skeptical about the ability of probiotics to influence the intestinal microbiome of poultry. This article discusses various modern studies that carry the opinions of foreign authors about the effectiveness of probiotics and their effect on the intestinal microbiome of poultry.
Analysis of the Anthrax outbreak in the Akmola region of Kazakhstan
Authors: Sushchikh V. Yu. , Yusupov M. R. , Dyusenov C. M. , Kanatov B. , Karimov A. A. 
Published: April 2023

Despite the ongoing preventive measures against anthrax, in Kazakhstan, as in other countries, this disease has not been eliminated. The system of supervision and control of anthrax provides for the identification of territories unfavorable for anthrax, the causes of animal diseases.The purpose of the study is a retrospective analysis of the anthrax outbreak in the territory of Kazakhstan in the Akmola region in 2019 to identify the causes of the outbreak, and the expected risks of its occurrence in the future, to improve veterinary and sanitary measures.Epizootological methods were used in the work, including a comparative historical and geographical description of anthrax outbreaks in the Akmola region.During the investigation of the outbreak, it was found that the grazing of animals was carried out on different pastures. Infection of people occurred in the village of Olginka during the forced slaughter and cutting of two heads of cattle. According to the information, in the village of Olginka, in the first days of September 2019, a bull and a cow were slaughtered. The owners are residents of the village of Olginka. A few days after the slaughter of the animals, the villagers involved in the slaughter fell ill with anthrax.When examining the landscape of the area, it was established that there are numerous colonies of rodent burrows throughout the pasture. According to local residents, a significant increase in the number of rodents was noted in 2019.Presumably, the infection of animals on pastures occurred due to the activation of previously unidentified anthrax burials. The removal to the surface of deep layers of soil contaminated with anthrax spores due to the presence of numerous rodent burrows in the pasture. Employees of the committee of veterinary control and supervision of the region, as well as local veterinary specialists, are recommended to vaccinate farm animals twice a year.
The problem of validation of toxicological models in pharmacy
Authors: Popova O. S. 
Published: April 2023

Animal toxicity testing is widely used in the chemical, pharmaceutical and research industries as a part of preclinical laboratory testing of substances to ensure that chemicals are safe for humans and animals. Under preclinical conditions, the safe and effective dose, acceptable dose, and exposure threshold of a substance can be established using mammals and rodents. There are enough materials on the introduction of biomodels in experiments. To summarize this knowledge, a polythematic abstract-bibliographic base was analyzed. The main attention was paid to such scientometric databases as: Web of Science Core Collection, Medline, PubMed, RSCI, as well as eLIBRARY.ru portal data for the last 10 years. An assessment of the statistical data and publication activity of the authors was made for the query modeling and ethics in veterinary medicine and medicine.The aim of the study was to analyze modern models and prospects for using new biomodels for experiments in pharmacology and toxicology.Having established protocols is important to ensure consistency between different studies within the same model, ensuring reproducibility and repeatability in experiments.Based on the analysis of literature sources over the past 10 years, it can be concluded that despite the large number of regulatory framework and transgenic laboratory animals with embedded human target genes in their genome, it is not possible to obtain an identity. Probably, the main bias in predictive toxicology will be made on neural networks and computer replacement of existing biomodels. Since, despite their relative accuracy, maintenance and feeding are costly, and the field of using animals in experiments is increasingly criticized and requires new approaches.
Evaluation of the prospects for the use of Danio Rerio (Zebrafish) as biological model in the context of the study of hepatotoxic effects
Authors: Ponamarev V. S. 
Published: April 2023

This article describes the morphological structure of the zebrafish liver and its comparison with the organization of the liver of mammals, known methods for inducing liver pathologies in these fish, and assesses the prospects for using Danio rerio (Zebrafish) as biological models in the context of studying hepatotoxic effects.The scientific novelty of the publication lies in the complexity of the ongoing review of existing studies in the field of using model animals to assess various hepatotoxic effects, identifying the most promising approaches from the point of view of veterinary hepatology for their further possible introduction into industry practice.The information retrieval methodology was based on such general scientific methods of cognition as: a review of specialized search engines and databases of scientific and research data (Scopus, WoS, PubMed) over the past 10 years, of which the most informative ones were selected, analysis of the identified results, their comparison by relevance.Summing up the results of the search, we can conclude that the results of relevant experiments indicate the promise of studying hepatotoxic effects on zebrafish, which represent a promising and cost-effective alternative to other model objects. Danio rerio can reproduce in detail and with high accuracy the patterns of occurrence, development and outcome of pathological processes in mammalian organs due to the high level of genetic preservation and similar morphology and functions of organs. It is believed that further technical development and characterization of these biomodels in the context of the study of hepatotoxicity will provide new insights into the molecular and cellular mechanisms underlying disease pathogenesis, thereby providing multiple opportunities for the identification and validation of new therapeutic targets and treatments.
LA MANZANILLA Y SUS PROPIEDADES MEDICINALES
Authors: Gómez Ugarte Magaly , Reyes Rojas Shirley , Paredes Choque Laura 
Published: April 2023

Para todo ser humano es indispensable conocer el fundamento de los productos naturales, los cuales pueden ser consumidos y aplicados en sus diferentes presentaciones, como infusiones, ungüentos y otros.
La manzanilla es una planta herbácea nativa y resistente a cambios climáticos con fácil adaptación geográfica. Uno de los problemas actuales en el área de la salud es la "automedicación" y el uso indiscriminado de medicamentos sin prescripción médica, que a futuro podrían desencadenar diversas patologías, así como en la resistencia a los antibióticos, por lo que recurrir al consumo de plantas naturales para el alivio de ciertas dolencias, son una buena alternativa.
Se realizó un estudio de tipo descriptivo, con el objetivo de determinar el principio activo de la manzanilla y las diferentes formas de preparación y/o posología para el consumo, que favorezcan al alivio de dolores estomacales, inflamaciones y otros, gracias a sus componentes como hidratos de carbono, mucílago, glucósidos flavónicos, ácidos grasos, vitamina C, ácidos orgánicos, alcoholes y pigmentos, que actúan como un eficaz calmante y desinflamante.
PROPIEDADES MEDICINALES DEL POMELO, BENEFICIOS NUTRICIONALES Y SU APLICACIÓN EN LA ESTETICA
Authors: Gómez Ugarte Magaly , Escalera Cruz David Angel , Peralta Mamani Lesly Eliana , Martinez Ayala Aleyda Abigail , Paredes Fernandez Dayana Lilian , Conde Camacho Yessica 
Published: April 2023

El pomelo es un fruto cítrico del género de las rutáceas. El pomelo es muy adecuado en la prevención degeneración de las progresiva enfermedades del organismo, resultantes como de la degeneración macular o los problemas cardiovasculares.
Tradicionalmente se ha utilizado para combatir los resfriados y la gripe, disminuyendo los síntomas de la enfermedad y acelerando el proceso de recuperación. Ideal para todas las enfermedades del aparato respiratorio. Sin embargo, también favorece la digestión de los alimentos, sobre todo aquellos ricos en grasas. Posee propiedades que estimulan la producción de bilis en el hígado y su expulsión por parte de la vesícula biliar. El extracto de las semillas del pomelo se puede usar como antiséptico natural ya que impide el crecimiento de hongos, bacterias y virus.
Con el presente trabajo de investigación se pretende informar a la población en general de los beneficios del pomelo y recomendar en su utilización como una alternativa de la medicina natural.
EFECTO DE LOS CUELLOS DE BOTELLA GENÉTICOS EN LAS POBLACIONES ORIGINARIAS DE AMÉRICA
Authors: Taboada Lugo Noel , Lardoeyt Ferrer Roberto 
Published: April 2023

América fue el último continente en ser poblado por humanos. Estas poblaciones originarias sufrieron severos cuellos de botella genéticos, durante los cuales el número de individuos decreció de forma notoria, posiblemente debido a los recursos limitados, a enfermedades y, en algunos casos, los efectos de las migraciones a largas distancias. Lo que dio como resultado que, dentro de la población originaria del continente americano, exista una baja diversidad genética y una gran diferenciación con las poblaciones nativas del resto de mundo.
Otro periodo clave en la historia de las poblaciones indígenas americanas fue la llegada de los europeos, que tuvo un impacto muy profundo en el acervo genético de la población amerindia; al originar cuellos de botella poblacionales causados por: las epidemias, la esclavitud, guerras y hambrunas.
En el análisis del cromosoma Y, es común encontrar al haplogrupo Q con frecuencias del 100% en Mesoamérica y Sudamérica; mientras que cerca del 97% de las poblaciones originarias de América tiene ADN mitocondrial de los haplogrupos distintivos A, B, C o D, todos de origen asiático. La principal característica genética que diferencia a los pueblos originarios de América de los demás grupos humanos del mundo, es la predominancia del grupo sanguíneo O.
SÍNDROME DE CUTTING (AUTOLESIONISMO)
Authors: Carvajal Oviedo Hugo Eduardo , Arancibia Andrade Boris , Díaz Nogales Jorge Ramiro , Salgueiro Apaza Geraldine 
Published: April 2023

El Síndrome de Cutting es el acto de auto lesionarse con el fin de alterar un estado de ánimo, terminar con un estado de confusión emocional o aliviar una situación que implique estrés infligiéndose un daño físico en el cuerpo. El propósito último no es el suicidio, tampoco obtener placer o como ritual para pertenecer a un grupo. Se observa frecuentemente en adolescentes y la ubicación corporal es generalmente en las muñecas y el medio es cualquier objeto afilado (ej. hoja de afeitar).
Desde el punto de vista las ciencias biológicas y neuroquímicas, este síndrome se relaciona con niveles bajos de serotonina. Entre los factores psicológicos predisponentes se tiene la existencia de abuso físico o sexual, negligencia física o emocional y condiciones familiares disfuncionales durante la infancia y adolescencia. El ciclo de desarrollo del síndrome indica que el paciento con Cutting necesitará cortarse cada vez as para obtener el mismo resultado. El abordaje de: estos pacientes es psicológico y psiquiátrico, el paciente requiere psicoterapia y farmacoterapia
COMPORTAMIENTO DE LA RESISTENCIA DE Escherichia coli AL CIPROFLOXACINO EN UROCULTIVOS DE PACIENTES DEL HOSPITAL VIRGEN DE COPACABANA, LA PAZ - BOLIVIA GESTIONES 2004, 2006 Y 2012
Authors: del Pozo Tatiana , Vaca Villanueva Kevin Luis , Zalles García Nicole Katherine 
Published: April 2023

La infección del tracto urinario es una infección bacteriana común y muchas veces pasa por un subregistro, lo cual que hace difícil reconocer su verdadera incidencia en el tiempo, por lo tanto se requiere un diagnóstico clínico y un urocultivo positivo confirmatorio. Recientemente, se observaron reportes en crecimiento referidos a la resistencia de Escherichia coli al Ciprofloxacino, por lo que este trabajo busca determinar el comportamiento del mismo en nuestro medio.
El trabajo se realizó en el Hospital Virgen de Copacabana. El estudio fue de tipo retrospectivo y descriptivo. Los principales resultados se tradujeron en un incremento paulatino de urocultivos positivos para resistente a Ciprofloxacino. Se analizaron 314 urocultivos en total, de los cuales, 151 presentaron reportes de resistencia al Ciprofloxacino.
Se comprueba el incremento en la frecuencia de urocultivos con E coli resistente a la Ciprofloxacino a través del tiempo, identificando la responsabilidad del uso antibiótico como esencial para el éxito terapéutico.
RESISTENCIA A QUINOLONAS EN AISLADOS CLÍNlCOS DE Escherichia coli UROPATOGÉNICA EN PACIENTES HOSPITALIZADOS Y AMBULATORIOS PROCESADOS EN EL LABORATORIO CLÍNlCO CENTRAL DE LA CIUDAD DE COCHABAMBA A PARTIR DEL MES DE SEPTIEMBRE A DICIEMBRE DE 2015
Authors: Villarroel Mirtha , Uriona Trigo Ximena 
Published: April 2023

Las infecciones del tracto urinario constituyen una de las enfermedades infecciosas más comunes a nivel mundial, que afectan principalmente al sexo femenino. El principal agente causante de estas infecciones es la Escherichia coli uropatogénica (UPEC) responsable en un 70-95% de los casos de infecciones del tracto urinario.
Es bien sabido que en nuestro medio muchas de las personas que sufren de un episodio de infección urinaria recurren a las farmacias en busca de un antibiótico que alivie su malestar; acción que da lugar a un fracaso terapéutico. Es por este motivo que este trabajo tiene como objetivo determinar la resistencia a las Quinolonas en aislados clínicos de Escherichia coli uropatogénica en pacientes hospitalizados y ambulatorios; procesados en el Laboratorio Clínico Central de la Ciudad de Cochabamba a partir del mes de septiembre a diciembre de 2015.
Se realizó un estudio del tipo no experimental, transversal, donde se tomaron en cuenta los datos proporcionados por el cuaderno de registro del laboratorio de 142 pacientes, cuyas edades oscilaban entre 18 a 94 años.
Se encontró que en el 76% de los pacientes infectados, la Escherichia coli presentó resistencia al Ácido Nalidíxico; en cambio sólo el 50% presentó resistencia frente a las fluoroquinolonas: Ciprofloxacina y Levofloxacina. Con respecto al estado de los pacientes, el 78% de la bacteria que infectó a los pacientes ambulatorios presentó resistencia al Acido Nalidíxico, frente al 64% que infectó a los pacientes internados. En cambio, la resistencia observada frente a la Ciprofloxacina y Levofloxacina fue de un 52% en ambulatorios y 36% en internados.
SOSIALISASI TENTANG PUBERTAS DAN PAPARAN AUDIO VISUAL PADA SISWI SMP PUJA HANDAYANI PALEMBANG TAHUN 2022
Authors: Deviliawati Atma 
Published: April 2023

ABSTRAK
Tumbuh kembang remaja bukan hanya, membesar dan meninggi, akan tetapi merupakan perubahan sedemikian sampai mencapai bentuk yang optimal. Bagi anak perempuan hal ini menjadi sangat penting yang pada saatnya akan mengalami proses reproduksi. Sekarang ini banyak wanita yang mengalami menarche pada usia 8 tahun, ada juga pada usia 9-10 tahun Secara teori ada banyak faktor yang mempengaruhi terjadinya pubertas dini pada remaja perempuan salah satunya adanya paparan audio visual. Kecanggihan teknologi saat ini, tentu saja seedikit banyak mempengaruhi pertumbuhan dan perkembangan remaja, paparan terhadap audio visual tentu ada dampak positif maupun negatifnya. Tujuan dari sosialisasi ini mengedukasi siswi tentang pubertas serta dampak dari paparan audio visual khususnya konten dewasa. Metode yang digunakan dengan memberikan sosialisasi metode ceramah dan diskusi serta membagikan leaflet. Kegiatan dilaksanakan pada tanggal 18-19 Juli 2022. Hasil sosialisasi didapatkan dari hasil pembagian angket sebelum sosialisasi didapatkan pengetahuan tentang pubertas dan paparan audio visual dari 33 siswi lebih banyak berpengetahuan kurang yaitu 28 orang (85%) dan pengetahuan baik sebanyak 5 orang (15%). Setelah dilakukan sosialisasi siswi yang berpengetahuan kurang mengenai pubertas dan paparan audio visual meningkat menjadi 33 orang ( 100 %), hal ini menunjukkan bahwa ada peningkatan pengetahuan tentang kualitas tidur sebelum dilakukan sosialisasi dan sesudah dilakukan sosialisasi. Saran kepada penyelenggara pendidikan untuk melakukan edukasi secara terjadual kepada semua siswa dengan melibatkan instansi terkait mengenai kesehatan reproduksi di masa pubertas.