bluuebunny/crossref_metadata_2025_split huggingface dataset:
Words of scents: a linguistic analysis of online perfume reviews
Authors: Nikitina Larisa , Furuoka Fumitaka 
Published: July 2023

Abstract
This study explored linguistic resources that people employ to express their perceptions and opinions of a fragrance. Several natural language processing (NLP) techniques were used, including sentiment analysis, topic modelling, and supervised classification. The data were collected from the website of Fragrantica, popular among perfume lovers, and the reviews pertained to a niche market fragrance. The findings from the sentiment analysis revealed that the positive reviews contained a greater percentage of lexis referring to the social world, social processes, sexuality, leisure, and mental states. In the negative reviews, the prevalent lexis concerned health, illness, and social conflict. The topic modelling analysis indicated that the positive reviews centred on issues related to the experience of wearing the perfume, its sensual character, and its olfactory qualities. The negative reviews focused on skin chemistry, the perfume notes, and physical reactions to the scent. The supervised classification analysis indicated notable differences in the frequency ratios of some lexical items in the positive and negative reviews.
On the stationarity and existence of moments of the periodic EGARCH process
Authors: Lescheb Ines , Slimani Walid 
Published: July 2023

AbstractIn this paper, we will consider periodicEGARCH⁡(p,p){\operatorname{EGARCH}(p,p)}(exponential generalized autoregressive conditional heteroscedastic) processes denoted byPEGARCH⁡(p,p){\operatorname{PEGARCH}(p,p)}. These processes are similar to the standard EGARCH processes, but include seasonally varying coefficients. We examine the probabilistic structure of an EGARCH-type stochastic difference equation with periodically-varying parameters. We propose necessary and sufficient conditions ensuring the existence of stationary solutions (in a periodic sense) based on a Markovian representation. The closed forms of higher moments are, under these conditions, established. Furthermore, the expressions for the Kurtosis coefficient and the autocorrelations of squared observations are derived. The general theory is illustrated by considering special cases such as the symmetric and the asymmetric cases of the second order PEGARCH model.
Analysis of heroin effects on calcium channels in rat cardiomyocytes based on transcriptomics and metabolomics
Authors: Su Liping , Liu Li , Ji Min , Hu Xiayun , Liang Min , Lu Ziyang , Wang Zhiguo , Guan Yaling , Xiao Jinling , Zhuang Mengjie , Zhu Sensen , Yang Long , Pu Hongwei 
Published: July 2023

Abstract
Heroin can cause damage to many human organs, possibly leading to different types of arrhythmias and abnormal electrophysiological function of the heart muscle and the steady state of calcium-ion channels. We explored cardiomyocytes treated with heroin and the effect on calcium-ion channels. Transcriptomics and metabolomics were used to screen for differential genes and metabolite alterations after heroin administration to jointly analyze the effect of heroin on calcium channels in cardiomyocytes. Cardiomyocytes from primary neonatal rats were cultured in vitro and were treated with different concentrations of heroin to observe the changes in morphology and spontaneous beat frequency and rhythm by a patch clamp technique. Transcriptomic studies selected a total of 1,432 differentially expressed genes, 941 upregulated and 491 downregulated genes in rat cardiomyocytes from the control and drug intervention groups. Gene Ontology functional enrichment showed that 1,432 differential genes selected by the two groups were mainly involved in the regulation of the multicellular organismal process, response to external stimulus, myofibril, inflammatory response, muscle system process, cardiac muscle contraction, etc. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that these genes were mainly concentrated in cardiac muscle contraction, osteoclast differentiation, adrenergic signaling in cardiomyocytes, dilated cardiomyopathy, hypertrophic cardiomyopathy, and other important pathways. Metabolomic testing further suggested that cardiomyocyte metabolism was severely affected after heroin intervention. After the treatment with heroin, the L-type calcium channel current I–V curve was up-shifted, the peak value was significantly lower than that of the control group, action potential duration 90 was significantly increased in the action potential, resting potential negative value was lowered, and action potential amplitude was significantly decreased in cardiomyocytes. In this study, heroin could cause morphological changes in primary cardiomyocytes of neonatal rats and electrophysiological function. Heroin can cause myocardial contraction and calcium channel abnormalities, damage the myocardium, and change the action potential and L-type calcium channel.
The crystal structure of 4-(3-carboxy-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4- dihydroquinolin-7-yl)-2-methylpiperazin-1-ium 2,5-dihydroxybenzoate methanol solvate, C27H32FN3O9
Authors: Lin Shu-Ting , Lou Can , Jiang Cheng-Jun 
Published: July 2023

Abstract
C27H32FN3O9, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 8.0932(4) Å, b = 11.8392(7) Å, c = 14.6782(8) Å, α = 87.860(3)∘, β = 76.795(2)∘, γ = 78.317(2)°, V = 1340.81(13) Å3, Z = 2, R
gt (F) = 0.0559, wR
ref (F
2) = 0.1537, T = 170 K.
The crystal structure of 4-aminiumbiphenyl benzenesulfonate, C18H17NO3S
Authors: Shi Chengzhe , Chen Xinlei , Jin Shouwen , Chen Shiyi , Wang Daqi 
Published: July 2023

Abstract
C18H17NO3S, monoclinic, Cc (no. 9), a = 32.036(3) Å, b = 7.2154(7) Å, c = 7.4283(8) Å, β = 99.943(2)∘, V = 1691.3(3) Å3, Z = 4, R

gt
(F) = 0.0343, wR

ref
(F
2) = 0.0821, T = 298 K.
Synthesis and crystal structure of 1-(7-hydroxy-3-(4-hydroxy-3-nitrophenyl)-4-oxo-4H-chromen-8-yl)-N,N-dimethylmethanaminiumnitrate, C18H17N3O9
Authors: Chen Hai-Lin , Yao Dong-Mei , Luo Ze-Ping , Wang Yan-Ping , Tang Yu-Mei 
Published: July 2023

Abstract
C18H17N3O9, monoclinic, P21/c (no. 14), a = 15.3768(3) Å, b = 7.4510(2) Å, c = 15.6673(5) Å, β = 102.700(3)∘, V = 1751.13(8) Å3, Z = 4, R

gt
(F) = 0.0405, wR

ref
(F

2
) = 0.1157, T = 100 K.
Bioconvection transport of upper convected Maxwell nanoliquid with gyrotactic microorganism, nonlinear thermal radiation, and chemical reaction
Authors: Li Shuguang , Nasir Muhammad , Waqas Muhammad , Abdelmohsen Shaimaa A. M. , Eldin Sayed M. , Abdullaev Sherzod Shukhratovich , Khan Waqar Azeem 
Published: July 2023

Abstract
The microorganisms’ concept has appealed substantial consideration of modern researchers because of its utilization in commercial and industrial products, for illustration, biofuel (prepared from the waste), drug delivery, and fertilizers. Keeping such utilizations of microorganisms in mind, an analysis based on gyrotactic microorganisms featuring the mixed convective nonlinear radiative Maxwell nanoliquid stagnation point flow configured by permeable stretching surface is presented. Boundary layer stretching flow subjected to transpiration effects is formulated. Modeling is based on Buongiorno’s nanoliquid model. This model captures Brownian diffusion along with thermophoresis aspects. Energy expression is formulated under nonlinear version of radiative heat-flux, heat source, thermal Robin conditions, and heat sink. Mass transport analysis is presented considering solutal Robin conditions and chemical reaction. In addition, the Robin conditions for motile microorganisms are also considered. The complex mathematical expressions of Maxwell liquid are simplified utilizing the Boundary layer concept and then suitable transformations assist to obtain the mathematical problems in ordinary differential forms. The analytical approach (that is homotopy analysis methodology) is utilized for computational analysis. The outcomes obtained are presented graphically and numerically. The detailed description of emerging physical non-dimensional parameters is included. Our findings indicate that the motile density field strongly boosted with the increment in Peclet number and microorganisms Biot number; however, they are suppressed with the increase in the values of bioconvection Schmidt number and motile microorganism concentration difference parameter.
3D printing of porous Ti6Al4V bone tissue engineering scaffold and surface anodization preparation of nanotubes to enhance its biological property
Authors: Fan Shiqi , Talha Mohd , Yu Xia , Lei Haoyuan , Tan Yi , Zhang Hui , Lin Yuanhua , Zhou Changchun , Fan Yujiang 
Published: July 2023

Abstract
Porous structures and surface morphology of bone tissue scaffolds play an important role in improving the biocompatibility and antibacterial properties for bone repair. In this study, we investigated the effect of different anodic oxidation parameters on the nanotubes morphology in 3D printed porous titanium scaffolds. Micron-scale pores were fabricated by 3D printing first, and then the nano-scale tubes were obtained via anodizing treatments. The results demonstrated that the morphology of the nanotubes depended on the anodic oxidation time and voltage, respectively. Longer anodic oxidation led to the formation of circle-like nanotubes, and the diameter of the nanotubes increased with the voltage. The scaffolds anodized at 30 V showed the best cell proliferation potential. The presence of nanotubes on the surface of scaffold altered the adhesion of bacteria so that it improved the antibacterial properties of scaffold. The formation of nanotubes improved the drug-loading ability of the scaffold, which are used for loading of minocycline antibacterial drugs. The proposed 3D printed porous Ti6Al4V scaffold with nanotubes surface modification showed obvious antibacterial effect, which is expected to have a promising application in antibacterial bone prosthesis.
Bioinspired ferromagnetic CoFe2O4 nanoparticles: Potential pharmaceutical and medical applications
Authors: Ansari Mohammad Azam , Govindasamy Rajakumar , Begum Mohammed Yasmin , Ghazwani Mohammed , Alqahtani Ali , Alomary Mohammad N. , Jamous Yahya F. , Alyahya Sami A. , Asiri Sarah , Khan Firdos Alam , Almessiere Munirah A. , Baykal Abdulhadi 
Published: July 2023

Abstract
The primary goal of this work was to develop a cost-effective, non-toxic, eco-friendly, and simple approach for the green synthesis of CoFe2O4 nanoparticles (NPs) using Aloe vera leaf extract by the sol–gel auto-combustion method. In order to figure out their structural, morphological, and magnetic properties, the synthesized NPs were characterized using X-ray diffraction (XRD), Fourier transform infrared (FTIR), scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscope (TEM), dynamic light scattering (DLS), zeta potential, and vibrating-sample magnetometer (VSM). XRD analysis showed that particles had a single-phase spinel crystalline structure with an average crystalline size of 33.5 nm. Under VSM studies, the produced NPs exhibit a soft ferromagnetic property. SEM revealed that the as-prepared NPs were agglomerated due to their magnetic behavior. To the best of our knowledge, the anticandidal, antibiofilm, antibacterial, and anticancer activities of CoFe2O4 NPs toward drug-resistant gram-positive and gram-negative bacteria, as well as fungal strains, have been comprehensively investigated for the first time. The synthesized NPs had a minimal inhibitory concentration of 0.25–0.75 mg/ml against the tested pathogens. CoFe2O4 NPs inhibited the biofilm formation by 37.3–61.8% in selected strains at concentrations of 0.125–0.5 mg/ml. It was observed that the NPs not only suppress biofilm formation but also eradicate established mature biofilms by 50.9–64.49% that was further supported by SEM. SEM analysis shows that NPs significantly inhibit the colonization and aggregation of tested biofilm strains. Light microscopic analysis revealed that NPs completely inhibit the development of hyphae and filaments in Candida albicans, which significantly attenuates their pathogenicity. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays and 4′,6-diamidino-2-phenylindole (DAPI) staining demonstrate that NPs significantly inhibit the proliferation of HCT-116 and HeLa cells. Furthermore, the SEM images of treated cells showed wrinkled and damaged cell walls, indicating the disruption and disorganization of the membrane. This study showed that the synthesized NPs were effective in inhibiting the growth of drug-resistant bacteria, candida, and their preformed biofilms as well. Thus, these NPs with broad-spectrum applications could be exploited in medical settings to diminish biofilm-based infections caused by these pathogenic strains.
The production of English monophthong vowels by Saudi L2 speakers
Authors: Algethami Ghazi 
Published: July 2023

Abstract
This study aims to describe the production of English monophthongs by nonnative Saudi speakers. It acoustically examined the production of English monophthongal vowels by Saudi second language (L2) speakers. Sixteen L2 participants produced twelve English monophthongs in carrier words. Comparable data were obtained in native Saudi Arabic and native Southern Standard British English to aid interpreting the L2 results. Formant frequencies and durations were measured for all vowels. Similar to Saudi Arabic, the English vowels produced by the Saudi L2 speakers occupied a smaller vowel space than the vowels produced by the native English speakers. There was overlap between many of the English vowel categories produced by the L2 speakers. However, the L2 speakers were found to employ similar durational characteristics to those employed by the native English speakers. L1 influence seems to play a major role in the L2 learners’ production of English vowels. The limited vowel space of the L2 speakers’ L1 appears to have limited their ability to produce the more acoustically peripheral English vowels.
Caste-ing White Supremacy
Authors: Bakrania Falu 
Published: July 2023

This paper examines the landmark 1923 Supreme Court case, United States v. Bhagat Singh Thind, alongside the Hindutva response to a 2020 landmark case, California Department of Fair Employment and Housing v. Cisco Systems Inc. These two cases are in many ways different: while Thind was confronting racial prerequisite laws concerning citizenship, the Hindu right (or Hindutva) is protesting the inclusion of caste in antidiscrimination laws. Yet, reading these together enables us to see how upper-caste South Asians have historically mobilized caste to uphold not only Brahminical, but also white supremacy. While much work on race and caste highlights the parallels between racism and casteism as descent-based discriminations, I illuminate how they intersect, shaping immigrant struggles to establish belonging and rights in the United States.
Caste served as a lynchpin for Thind’s case. Thind and his legal team used caste to prove the purity of Thind’s “Aryan blood” and therefore his whiteness and eligibility for citizenship. In doing so, they also reproduced anti-Blackness. Though the Supreme Court rejected Thind’s argument, it retained the idea that caste, race, and blood are linked. Nearly a century later, Hindutva’s response to Cisco appears to want to abolish caste by not naming it. Yet, read alongside the rise of the language of “merit” and “castelessness” in India, and the move to “colorblindness” and model minority racialization in the United States, their “caste-blind” agenda bolsters both Brahminical and white supremacy.
A non‐proteolytic release mechanism for HMCES‐DNA‐protein crosslinks
Authors: Donsbach Maximilian , Dürauer Sophie , Grünert Florian , Nguyen Kha T , Nigam Richa , Yaneva Denitsa , Weickert Pedro , Bezalel‐Buch Rachel , Semlow Daniel R , Stingele Julian 
Published: July 2023

AbstractThe conserved protein HMCES crosslinks to abasic (AP) sites in ssDNA to prevent strand scission and the formation of toxic dsDNA breaks during replication. Here, we report a non‐proteolytic release mechanism for HMCES‐DNA‐protein crosslinks (DPCs), which is regulated by DNA context. In ssDNA and at ssDNA‐dsDNA junctions, HMCES‐DPCs are stable, which efficiently protects AP sites against spontaneous incisions or cleavage by APE1 endonuclease. In contrast, HMCES‐DPCs are released in dsDNA, allowing APE1 to initiate downstream repair. Mechanistically, we show that release is governed by two components. First, a conserved glutamate residue, within HMCES' active site, catalyses reversal of the crosslink. Second, affinity to the underlying DNA structure determines whether HMCES re‐crosslinks or dissociates. Our study reveals that the protective role of HMCES‐DPCs involves their controlled release upon bypass by replication forks, which restricts DPC formation to a necessary minimum.
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR+ neurons
Authors: Zhang Zhi‐Jun , Shao Han‐Yu , Liu Chuan , Song Hao‐Lin , Wu Xiao‐Bo , Cao De‐Li , Zhu Meixuan , Fu Yuan‐Yuan , Wang Juan , Gao Yong‐Jing 
Published: July 2023

AbstractA11 dopaminergic neurons regulate somatosensory transduction by projecting from the diencephalon to the spinal cord, but the function of this descending projection in itch remained elusive. Here, we report that dopaminergic projection neurons from the A11 nucleus to the spinal dorsal horn (dopaminergicA11‐SDH) are activated by pruritogens. Inhibition of these neurons alleviates itch‐induced scratching behaviors. Furthermore, chemogenetic inhibition of spinal dopamine receptor D1‐expressing (DRD1+) neurons decreases acute or chronic itch‐induced scratching. Mechanistically, spinal DRD1+ neurons are excitatory and mostly co‐localize with gastrin‐releasing peptide (GRP), an endogenous neuropeptide for itch. In addition, DRD1+ neurons form synapses with GRP receptor‐expressing (GRPR+) neurons and activate these neurons via AMPA receptor (AMPAR). Finally, spontaneous itch and enhanced acute itch induced by activating spinal DRD1+ neurons are relieved by antagonists against AMPAR and GRPR. Thus, the descending dopaminergic pathway facilitates spinal itch transmission via activating DRD1+ neurons and releasing glutamate and GRP, which directly augments GRPR signaling. Interruption of this descending pathway may be used to treat chronic itch.
Q&A: Coding for Pediatric Echocardiography
Authors:   American Academy of Pediatrics
Published: July 2023

Current Procedural Terminology (CPT®) includes a variety of codes for reporting the performance and/or interpretation and report of echocardiography, including codes for different echocardiography procedures and add-on codes for imaging techniques that are separately reported, when performed. This article provides answers to common questions about code selection for these services. Topics include the following:
Professional and technical components of echocardiography Echocardiography and critical care services on the same date Echocardiography for congenital anomaly of the heart Complete versus limited echocardiography Stress echocardiography Documentation
Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism
Authors: Lee Hayoon , Lee Dohee , Park Jooyoung , Yun Taesik , Koo Yoonhoi , Chae Yeon , Kang Byeong-Teck , Yang Mhan-Pyo , Kim Hakhyun 
Published: July 2023

AbstractA 16-year-old castrated male Persian cat was presented with weight loss, anorexia and dyspnoea. Tachycardia and tachypnoea were observed upon presentation. The cat was previously diagnosed with hyperthyroidism and left ventricular hypertrophy and received methimazole, but was subsequently not followed up and treated appropriately. Thoracic radiography revealed mild pleural effusion, interstitial lung pattern, moderate cardiomegaly and moderate-to-severe dilation of the pulmonary artery and pulmonary vein. On echocardiography, the left ventricular hypertrophy, identified earlier, shoed partial regression. Therefore, the previous myocardial hypertrophy was diagnosed as a hypertrophic cardiomyopathy phenotype related to hyperthyroidism. ST-segment elevation was identified on electrocardiography, and the thyroid profile examination revealed increased total thyroxine and free thyroxine and decreased thyroid-stimulating hormone levels, suggesting myocardial injury and uncontrolled hyperthyroidism, respectively. In addition, normal N-terminal pro-B-type natriuretic peptide and high cardiac troponin I levels were found. Based on these findings, the observed congestive heart failure was considered as a sequel of myocardial injury caused by uncontrolled hyperthyroidism. Clinical signs resolved after intravenous administration of furosemide and butorphanol, oxygen supply and thoracocentesis. Furosemide and pimobendan were additionally administered, and the cat was discharged. This case demonstrates that myocardial damage due to chronic uncontrolled hyperthyroidism may cause heart failure in cats.
Ketahanan 50 galur harapan padi terhadap penyakit tungro
Authors: Khaerana Khaerana , Rosida Nur , Komalasari Ema 
Published: July 2023

Green leafhoppers is the main vector for tungro disease infection. Tungro is a rice disease which is characterized with stunted plants, yellow orange leaves, and a reduced number of tillers. The research aimed to determine the resistance of 50 rice lines to tungro disease. This research was conducted in Augmented Design with 5 blocks. The observation was held on 50 expected tungro resistant rice lines, with 2 check varieties, Inpari 36 and Ciherang. Experiment in field were included observation on number of imago and nymph green leafhoppers for each line test during 2, 4, 6 and 8 weeks after planting, and the incidence of tungro infection. Leaf which indicated tungro infection was isolated for its DNA and PCR analysis at the virology laboratory of the tungro disease research station. The results showed that the number of green leafhopper (imago and nymph) for the 43 test lines were less than the check varieties of 5% LSI test. The incidence of tungro was very low in the field. The results of the PCR test showed that the rice line infected by tungro virus was only rice line number 7. Thus, there are 43 promizing lines that can be recommended for future research to obtain tungro resistant varieties.ABSTRAK Wereng hijau merupakan vektor utama penyebaran penyakit tungro. Tungro merupakan penyakit padi dengan ciri utama tanaman kerdil, daun berwarna kuning oranye, dan jumlah anakan berkurang. Tujuan penelitian ini adalah untuk mengetahui ketahanan 50 galur padi terhadap penyakit tungro. Penelitian ini menggunakan rancangan augmented yang terbagi dalam 5 blok. Pengamatan dilakukan terhadap 50 galur padi harapan tahan tungro, dengan 2 varietas cek, yaitu Inpari 36 dan Ciherang. Penelitian di lapangan meliputi pengamatan terhadap jumlah imago dan nimfa wereng hijau pada masing-masing galur uji selama 2, 4, 6 dan 8 minggu setelah tanam, serta insidensi serangan tungro. Sampel daun tanaman yang terindikasi terserang tungro diuji untuk mengkonfirmasi keberadaan virus tungro secara molekuler dengan isolasi DNA (PCR) dan RNA (RT/PCR) di laboratorium virologi Loka Penelitian Penyakit Tungro. Hasil penelitian menunjukkan terdapat 43 galur uji yang signifikan lebih sedikit jumlah wereng hijau (nimfa dan imago) dibanding varietas cek pada uji LSI 5%. Insidensi tungro sangat rendah di lapangan. Hasil uji PCR menunjukkan bahwa galur uji yang terinfeksi virus tungro RTSV hanya galur nomor 7. Dengan demikian, terdapat 43 galur yang direkomendasikan pada penelitian berikutnya untuk memperoleh varietas tahan tungro.