bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technology-oriented M&A, market reaction and innovation output
Authors: Yao Yi , Ling Yue , Xu Yafei 
Published: April 2023

PurposeThe purpose of technology mergers and acquisitions (M&A) is to achieve innovation. The authors use the data from the China Patent Research System of China National Intellectual Property Administration to classify technical correlations into three types: similar, complementary and nonrelatedness (cross-sectoral category). And the authors explore three issues: the market reaction to technology-oriented M&A, the impact of technology-oriented M&A on goodwill and how technology-oriented M&A affects innovation.Design/methodology/approachThe authors use data from China Patent Research System of China National Intellectual Property Administration to classify technical correlations into three types: similar, complementary and nonrelatedness (cross-sectoral category). And the authors explore three issues: the market reaction of technology-oriented M&A, the impact of technology-oriented M&A on goodwill and how technology-oriented M&A affects innovation. The empirical research shows that the cross-sectoral M&A is popular in the market and is positively correlated with cumulative abnormal return (CAR) and premium rate of M&A. However, the technology-similarity M&A, which is committed to in-depth exploration of original technology, is negatively correlated with CAR and goodwill.FindingsThe empirical research shows that cross-sectoral M&A is popular in the market and is positively correlated with CAR and premium rate of M&A. However, the technology-similarity M&A, which is committed to in-depth exploration of original technology, is negatively correlated with CAR and goodwill. In addition, empirical results show that there is an inverted U-shaped relationship between technology-oriented M&A and innovation output, and the inflection points are 41.8%, 48.9% and 38.8%, respectively.Originality/valueThe research contributions of this paper are as follows: first, most domestic studies simply and roughly measure the degree of technical relevance based on whether the firms belong to the same industry and whether there is common knowledge between them, but the authors provide a more accurate measure of technology-oriented M&A. Second, in the research on the economic consequences of technology-oriented M&As, a large number of literatures have mainly focused on the innovation performance of the acquirer after deals, including the number of patent applications, the number of patent citations, innovation output, etc., and they pay less attention to its impact on the market reaction and goodwill.
Does the “big tent” include non-academics? Social media content creators conducting critical scholarship
Authors: Sankofa Nicole 
Published: April 2023

Purpose LeftTube – a loosely connected community of left-leaning content creators on YouTube – includes a subsection of video essayists that conduct scholarly work seemingly adjacent to critical research. Exploring this digital community of critical scholars may precipate opportunities for collaboration and reciprocal learning to better academic qualitative research approaches. Therefore, the purpose of this exploratory study is to (1) examine if and how this digital community engages in critical scholarship, and (2) initiate a call for academic qualitative scholars to watch this digital space as a potential source of collaboration, an opportunity for co-learning and consideration for inclusion in the qualitative “big tent”.Design/methodology/approach Using an algorithm-based sampling procedure, 143 videos were sampled across 23 Black women content creators. Videos were analyzed for characteristics of critical research using multimodal-ethnographic semiotic analysis.Findings Findings suggest that 11 strategies of critical scholarship were used with themes of knowledge production and ethical framework. Such results indicate that this subsection of LeftTube video essayists are conducting critical scholarship.Originality/value The most significant implication is the expansion of the qualitative “big tent” to include international social media content creators who conduct social science research. This would have many benefits to academic qualitative researchers, including learning how the studied community (1) makes critical scholarship impactful and influential in civil discourse, (2) mobilizes critical language, and (3) resists neoliberal and capitalist systems attempting to marginalize critical research.
Full‐cost accounting and redefining the cost of food: Implications for agricultural economics research
Authors: von Braun Joachim , Hendriks Sheryl L. 
Published: April 2023

AbstractFood systems have significant externalities that are not reflected in market prices. A first step to correct parts of these externalities is to make them transparent through “true‐” or full‐cost accounting. Estimates of the external health and environmental costs of food systems at a global level suggest that they may be about two times larger than food valued at market prices, that is, about 20 trillion US$ of externalities versus 9 trillion US$ of food value in the markets. The agricultural economics profession is challenged to move the true cost research agenda forward by identifying realistic pathways for internalizing some of the large food system externalities. Moving from true cost accounting (TCA) to policy action needs to involve citizens and policy‐making bodies because internalizing externalities requires buy‐in. This relates for instance, to policy instruments such as product labeling, nudging, and differential taxes and subsidies to incentivize healthy diets and disincentivize food waste. Agricultural economics will need to accompany the implementation of any true cost approaches with scrutiny in terms of the efficiency, welfare, ecological, and distributional effects of such policies.
Using the Cardiff model to reduce late‐night alcohol‐related presentations in regional Australia
Authors: Baker Tim , Taylor Nicholas , Kloot Kate , Miller Peter , Egerton‐Warburton Diana , Shepherd Jonathan 
Published: April 2023

AbstractIntroductionThe Cardiff model is a data sharing approach that aims to reduce the volume of intoxicated patients in emergency departments (EDs). This approach has not been tested in a rural setting.ObjectiveThis study assessed whether this approach would reduce the number of alcohol‐associated presentations during high‐alcohol hours (HAH) in a regional ED.DesignFrom July 2017, people over the age of 18 attending the ED were asked by the triage nurse (1) whether they had consumed alcohol in the past 12 h, (2) their typical alcohol consumption level, (3) the location where most alcohol was purchased and (4) the location of the last drink. From April 2018, quarterly letters were sent to the top five venues reported within the ED. Deidentified, aggregated data were shared with local police, licensing authorities and local government, identifying the top five venues reported in the ED and providing a summary of alcohol‐related attendances to the ED. Interrupted time series analyses were used to estimate the influence of the intervention on monthly injury and alcohol‐related ED presentations.FindingsITS models found that there was a significant gradual decrease in the monthly rate of injury attendances during HAH (Coefficient = −0.004, p = 0.044). No other significant results were found.DiscussionOur study found that sharing last drinks data collected in the ED with a local violence prevention committee was associated with a small, but significant reduction in the rate of injury presentations compared with all ED presentations.ConclusionThis intervention continues to have promise for reducing alcohol‐related harm.
Propensity score‐matched analysis of the short‐term outcomes of robotic versus laparoscopic surgery for rectal cancer
Authors: Obatake Masayoshi , Hotchi Masanori , Ishimura Naho , Kanzaki Masayuki , Yoshikawa Masato , Tokuda Kazunori , Watanabe Miya , Kotegawa Hiroshi , Yoshiyama Hirotsugu , Ohtani Hiromi , Harada Masamitsu 
Published: April 2023

AbstractPurposeThe advantages of robot‐assisted rectal surgery (RARS) over conventional laparoscope‐assisted rectal surgery (LARS) remain controversial. This study was performed to compare the short‐term outcomes of RARS and LARS.MethodsWe retrospectively analyzed data of 207 patients who had undergone either RARS (n = 97) or LARS (n = 110) for rectal cancer (RC) from 2018 to 2020. A 1:1 matched propensity score‐matched analysis was performed and the surgical outcomes of the two groups compared.ResultsAfter matching, a well‐balanced cohort of 136 patients was analyzed (n = 68 in each group), and there was no significant difference in the median operative time. The RARS group had less intraoperative blood loss than the LARS group. There were no significant differences in length of postoperative hospital stay or complication rate between the two groups. In the subgroup of lower RC, defined as the inferior edge of the tumor being within the rectum distal to the peritoneal reflection, the rate of sphincter preservation was higher in the RARS group (81.8% vs. 44.4%, p = 0.021).ConclusionThis study shows that RARS is a safe and feasible approach for RC compared with LARS, RARS having the advantage of more often preserving the sphincter.
High salt induces cognitive impairment via the interaction of the angiotensin II‐AT1 and prostaglandin E2‐EP1 systems
Authors: Kubota Hisayoshi , Kunisawa Kazuo , Wulaer Bolati , Hasegawa Masaya , Kurahashi Hitomi , Sakata Takatoshi , Tezuka Hiroyuki , Kugita Masanori , Nagao Shizuko , Nagai Taku , Furuyashiki Tomoyuki , Narumiya Shuh , Saito Kuniaki , Nabeshima Toshitaka , Mouri Akihiro 
Published: April 2023

Background and PurposeHigh salt (HS) intake has been associated with hypertension and cognitive impairment. It is well known that the angiotensin II (Ang II)‐AT1 receptor and prostaglandin E2 (PGE2)‐EP1 receptor systems are involved in hypertension and neurotoxicity. However, the involvement of these systems in HS‐mediated hypertension and emotional and cognitive impairments remains unclear.Experimental ApproachMice were loaded with HS solution (2% NaCl drinking water) for 12 weeks, and blood pressure was monitored. Subsequently, effects of HS intake on emotional and cognitive function and tau phosphorylation in the prefrontal cortex (PFC) and hippocampus (HIP) were investigated. The involvement of Ang II‐AT1 and PGE2‐EP1 systems in HS‐induced hypertension and neuronal and behavioural impairments was examined by treatment with losartan, an AT1 receptor blocker (ARB), or EP1 gene knockout.Key ResultsWe demonstrate that hypertension and impaired social behaviour and object recognition memory following HS intake may be associated with tau hyperphosphorylation, decreased phosphorylation of Ca2+/calmodulin‐dependent protein kinase II (CaMKII), and postsynaptic density protein 95 (PSD95) expression in the PFC and HIP of mice. These changes were blocked by pharmacological treatment with losartan or EP1 receptor gene knockout.Conclusions and ImplicationsOur findings suggest that the interaction of Ang II‐AT1 receptor and PGE2‐EP1 receptor systems could be novel therapeutic targets for hypertension‐induced cognitive impairment.
Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
Authors: Ayyolath Aravind , Kallingal Anoop , Kundil Varun Thachan , Suresh Akshay Maniyeri , Jayadevi Variyar E. 
Published: April 2023

AbstractAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day‐to‐day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability. Current pharmacotherapy for AD includes compounds that aim to increase neurotransmitters at nerve endings. This can be achieved by cholinergic neurotransmission through inhibition of the cholinesterase enzyme. The current research aims to find natural substances that can be used as drugs to treat AD. The present work identifies and explains compounds with considerable Acetylcholinesterase (AChE) inhibitory activities. The pigment was extracted from thePenicillium mallochiiARA1 (MT373688.1) strain using ethyl acetate, and the active compound was identified using chromatographic techniques followed by structural confirmation with NMR. AChE inhibition experiments, enzyme kinetics, and molecular dynamics simulation studies were done to explain the pharmacological and pharmacodynamic properties. We identified that the compound sclerotiorin in the pigment has AChE inhibitory activity. The compound is stable and can bind to the enzyme non‐competitively. Sclerotiorin obeys all the drug‐likeliness parameters and can be developed as a promising drug in treating AD.
Machinic assemblages—The role of school policies in producing children's sense of agency
Authors: Kokko Anna Kristiina , Paananen Maiju , Hirsto Laura 
Published: April 2023

AbstractThis paper presents an account of how children's sense of agency is produced in machinic assemblages. The ethnographic data used in this study originated in one elementary school classroom. By utilising children's own expressions of their agency and by examining the machinic assemblages in which these expressions were produced, we demonstrate that school policies are not merely a background for schools' mundane practices. Rather, when combined with other elements in a school setting, policies have heterogeneous consequences for children's sense of agency.
Reframing Cognitive Science as a Complexity Science
Authors: Favela Luis H. , Amon Mary Jean 
Published: April 2023

AbstractComplexity science is an investigative framework that stems from a number of tried and tested disciplines—including systems theory, nonlinear dynamical systems theory, and synergetics—and extends a common set of concepts, methods, and principles to understand how natural systems operate. By quantitatively employing concepts, such as emergence, nonlinearity, and self‐organization, complexity science offers a way to understand the structures and operations of natural cognitive systems in a manner that is conceptually compelling and mathematically rigorous. Thus, complexity science both transforms understandings of cognition and reframes more traditional approaches. Consequently, if cognitive systems are indeed complex systems, then cognitive science ought to consider complexity science as a centerpiece of the discipline.
Diagnosis and unsuccessful management of iatrogenic fungal septic arthritis caused byWickerhamomyces anomalous(formerlyCandida pelliculosa) and concurrent osteochondral lesion in Ireland
Authors: Duggan Michael , Gibbons James , Offereins Henk , Fogarty Ursula , Schofield Warren 
Published: April 2023

SummaryEquine septic fungal arthritis is poorly documented in the literature. There is an absence of efficacy and safety data for antifungal medications, highlighting the importance of documenting this case. A 15‐year‐old Irish sport horse gelding presented 4/5 (AAEP) left hindlimb lame 13 days after intra‐articular medication of the left tarsocrural joint with triamcinolone and hyaluronic acid. Radiography revealed an osteochondral fragment at the distal intermediate ridge of the tibia and shallow subchondral bone defect on the medial trochlear ridge. Synoviocentesis yielded a turbid sample with an elevated total nucleated cell count (49 × 109cells/L; total neutrophil count of 62.8%). Arthroscopic lavage of the tarsocrural joint (TCJ) was performed. Ceftriaxone was administered and systemic antimicrobials initiated. The fungusWickerhamomyces anomaluswas identified on culture. The horse was subsequently intensively treated with antimicrobial and antifungal medications, both systemically and intra‐articularly over the following 60 plus days. Multiple subsequent synovial cultures revealed the persistence of the fungal organism, until a negative culture on day 55. However, on day 113, a grade 5/5 lameness was present, and a further positive synovial fungal culture. Radiographs revealed a lytic lesion at the distal tibia with marked progression. The horse was euthanised on day 126.
Diel variation in insect‐dominated temperate pond soundscapes and guidelines for survey design
Authors: Greenhalgh Jack A. , Genner Martin J. , Jones Gareth 
Published: April 2023

Abstract

Passive acoustic monitoring has been used for decades as a non‐invasive tool for quantifying biodiversity in terrestrial and marine ecosystems. Recently, there has been increased interest in the potential for the method to survey freshwater biodiversity. Fundamental aspects of freshwater soundscape phenology, however, often remain poorly understood, despite their importance for suitable survey design.

To gain a greater understanding of daily acoustic variation in aquatic insect‐dominated temperate pond soundscapes, 840 hr of underwater sound recordings were collected from five ponds in the southwest of the U.K. We calculated six commonly used acoustic indices to investigate diel trends and evaluated the suitability of each acoustic index to identify biologically complex pond soundscapes. In addition, macroinvertebrates were collected from each pond to investigate potential drivers of diel soundscape variation.

The ponds studied possessed clear patterns of daily acoustic variation, with acoustic activity typically peaking between 02:00 and 04:00 and around the solar noon. Acoustic Entropy showed the greatest variation between day and night soundscapes and was best suited for detecting overall daily acoustic variation in the study ponds. However, the Normalised Difference Soundscape Index and the Bioacoustic Index captured strong diel variation in aquatic insect‐dominated soundscapes. Furthermore, we calculated that a minimum hydrophone deployment time of 24 hr is required to ensure that soundscape variation is adequately captured.

This study provides an increased understanding of daily acoustic variation in insect‐dominated temperate pond soundscapes, enabling us to provide guidelines for the design and implementation of future passive acoustic monitoring surveys. We suggest that a minimum of 24 hr is required to adequately capture pond soundscape variation. This will increase the chance of detecting key soniferous species in the soundscape and enable more accurate assessments of temperate pond soundscapes.
Responses of population structure and genomic diversity to climate change and fishing pressure in a pelagic fish
Authors: Mendoza‐Portillo Verónica , García‐De León Francisco J. , von der Heyden Sophie 
Published: April 2023

AbstractThe responses of marine species to environmental changes and anthropogenic pressures (e.g., fishing) interact with ecological and evolutionary processes that are not well understood. Knowledge of changes in the distribution range and genetic diversity of species and their populations into the future is essential for the conservation and sustainable management of resources. Almaco jack (Seriola rivoliana) is a pelagic fish with high importance to fisheries and aquaculture in the Pacific Ocean. In this study, we assessed contemporary genomic diversity and structure in loci that are putatively under selection (outlier loci) and determined their potential functions. Using a combination of genotype–environment association, spatial distribution models, and demogenetic simulations, we modeled the effects of climate change (under three different RCP scenarios) and fishing pressure on the species' geographic distribution and genomic diversity and structure to 2050 and 2100. Our results show that most of the outlier loci identified were related to biological and metabolic processes that may be associated with temperature and salinity. The contemporary genomic structure showed three populations—two in the Eastern Pacific (Cabo San Lucas and Eastern Pacific) and one in the Central Pacific (Hawaii). Future projections suggest a loss of suitable habitat and potential range contractions for most scenarios, while fishing pressure decreased population connectivity. Our results suggest that future climate change scenarios and fishing pressure will affect the genomic structure and genotypic composition of S. rivoliana and lead to loss of genomic diversity in populations distributed in the eastern‐central Pacific Ocean, which could have profound effects on fisheries that depend on this resource.
Associations between adiponectin and leptin levels and skeletal muscle mass and myosteatosis in older adults: The Shimanami Health Promoting Program study
Authors: Tabara Yasuharu , Okada Yoko , Ochi Masayuki , Ohyagi Yasumasa , Igase Michiya 
Published: April 2023

AimIdentifying plasma molecules associated with skeletal muscle properties can elucidate the pathophysiology of sarcopenia. Because adipocytokines are a promising candidate marker, the current study aimed to clarify the possible associations between adiponectin and leptin levels and mid‐thigh muscle cross‐sectional area and mean attenuation value, which are indices of muscle mass and fat deposition in muscle, respectively.MethodsThe current study included 1440 older Japanese adults (mean age 69.3 years). Mid‐thigh skeletal muscle cross‐sectional area and mean attenuation value were evaluated through computed tomography scan. A low attenuation value showed a greater fat deposition in muscle. Circulating adiponectin and leptin levels were assessed using blood specimens collected during the baseline investigation.ResultsPlasma leptin level was inversely correlated with muscle cross‐sectional area, but not with attenuation value. The association with cross‐sectional area was independent of possible confounding factors including body size (Q1: reference; Q2: β = −0.032, P = 0.033; Q3: β = −0.064, P < 0.001; Q4: β = −0.111, P < 0.001). In contrast, adiponectin level was independently and inversely associated with attenuation value (Q1: reference; Q2: β = −0.044, P = 0.122; Q3: β = −0.080, P = 0.006; Q4: β = −0.159, P < 0.001), but not with cross‐sectional area. These associations between adipocytokine levels and muscle properties were independent of abdominal fat area and insulin resistance.ConclusionsThere were adiposity‐ and insulin resistance‐independent associations between adipocytokines levels and skeletal muscle mass and fat deposition in muscle, suggesting an involvement of adipocytokines in muscle properties. Geriatr Gerontol Int 2023; 23: 444–449.