bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Perceived Social Support and Resilience in Predicting the Mental Health of Healthcare Professionals During the COVID-19 Pandemic: A Study from Indonesia
Authors: Siswadi Ahmad Gimmy P. , Shabrina Arina , Djunaidi Achmad , Iskandarsyah Aulia 
Published: December 2022

Background:
The COVID-19 pandemic had a tremendous impact on Healthcare Professionals (HCPs). Social support and resilience were seen as protective factors for mental health problems. This study aimed to investigate the role of perceived social support and resilience in predicting Healthcare Professionals’ mental health during the outbreak in Indonesia.

Methods:
A digital self-reported survey was completed by 202 HCPs (143 women and 59 men) during the outbreak. A cross-sectional study was applied, and participants were recruited through a purposive sampling technique. The online survey collected information on sociodemographic, perceived social support, resilience, and mental health problems. Perceived social support was measured by The Multidimensional Scale of Perceived Social Support (MSPSS), resilience by the Connor-Davidson Resilience Scale (CD-RISC)–10, and mental health problems by the Self-Report Questionnaire (SRQ). Multivariate regression was applied to analyze the data.

Results:
Results indicated that a high resilience score was associated with low scores for depression, anxiety, and somatoform symptoms (β = -4.72, p = 0.000). On the contrary, perceived social support did not predict mental health or PTSD symptoms (β = -0.56, p = 0.412).

Conclusion:
Considering the role of resilience in reducing mental health problems, we suggest government and health authorities design an intervention program to increase HCPs’ resilience.
The Present Status of Respectful Maternity Care during Labor and Childbirth in Jordan: A Cross-sectional Study
Authors: AbuAlrub Salwa , Abu-Baker Nesrin N. , Abu Baker Muhammed , Abu Musameh Hanan 
Published: December 2022

Background
Exploring the status of respectful maternity care (RMC) during labor and childbirth helps in determining the quality of maternity care. Therefore, this study aimed to investigate the perception of pregnant women about RMC that they received during labor and childbirth and to evaluate the determinants of RMC perception.

Method
A cross-sectional descriptive design was used in this study. A convenience sample of 310 participants from two major hospitals in northern Jordan completed the RMC questionnaire. Thereafter, multiple regression was performed to identify the determinants of RMC perception.

Results
The mean score of all the items of the questionnaire was 2.83 out of 4 (SD = 0.33), which indicated that the women experienced a moderate level of RMC. The lowest mean scores were obtained for the quality of healthcare (mean= 2.63, SD= .38), 48.7% and 56.8% of the participants indicated that they were not allowed to move or eat and drink during the first stage of labor, respectively. In addition to the right to information and informed consent (mean= 2.67 ± 0.54), 56.8% of the participants revealed that staff did not introduce themselves. Women with high family income or assistance from a midwife reported significantly higher RMC scores compared to those with low family income or those tended by doctors (p ≤ 0.05).

Conclusion
Immediate action is needed to improve and support RMC as a critical component of maternal care by adopting standardized measures, and training healthcare providers to practice the code of ethics as a core component of RMC.
Neuropilin-2 Inhibits Drug Resistance and Progression of Melanoma
Involving the MiR-331-3p Regulated Cascade
Authors: Liu Dandan , Yang Jing , Xie Qun , Zhang Ruirui , Hu Qiang , Shan Chao , Li Xiaohan 
Published: December 2022

Background:
MicroRNAs (miRs) are small noncoding RNAs that are crucial in the
development and progression of tumours. Melanoma is an aggressive form of skin cancer and is
resistant to most of the chemotherapeutic agents. However, the role of miRs in melanoma remains
poorly studied.

Objective:
The work aimed to demonstrate that miR-331-3p is downregulated in melanoma
against the benign melanocytic nevi.

Methods:
RT-PCR analysis was performed for the expression of proteins; cell proliferation and
wound healing assays were carried out. Flow cytometry study was conducted for cell cycle analysis;
colony formation assay was performed by soft agar method. For developing a tumour xenograft
model, nu/nu mice were selected.

Results:
Up-regulation of miR-331-3p in melanoma cells decreased cell proliferation, cell migration,
and also drug resistance. Over-expression of miR-331-3p resulted in suppression of NRP2
and up-regulation of E-cadherin levels. Moreover, the levels of MDR1, ABCG-2, and ABCG-5
were decreased. However, the knockdown of NRP2 demonstrated similar effects as that of miR-
331-3p overexpression in tumour cells. Overexpression of miR-331-3p caused significant inhibition
of tumour growth and its metastasis in mice model of melanoma, which was associated with
depletion of NRP2 protein and increased expression of E-cadherin. However, the effects of miR-
331-3p on the migration, cell proliferation, and self-renewal were overturned by the upregulation
of NRP2, which also resulted in the inhibition of E-cadherin and overexpression of MDR-1,
ABCG-2, and ABCG-5.

Conclusion:
The findings point out the key role of miR-331-3p in the progression and drug resistance
of melanoma involving NRP2.
Phytochemical, Medicinal, and Green Approaches of Allamanda cathartica L.: A
Mini Review
Authors: Prakash Sharma Ishwar , Balkrishna Acharya , Saini Akansha , Bhandari Rachna , Arya Vedpriya 
Published: December 2022

Abstract:
Allamanda cathartica L. belongs to the family Apocynaceae and is a traditionally valuable medicinal plant that has been commonly used in the
traditional medicinal system and contributes to the native healthcare system in various parts of the world. This plant is renowned for its
antibacterial and anticancer effects and its usage in the treatment of jaundice, diabetes, hypertension, and polio. All of the economically and
medicinally essential plant parts of this species are used in the preparation of a potent cathartic. This review focused on and intended to highlight
the most current knowledge about A. cathartica, including its important ethnomedicinal, modern medicinal, and phytochemical potential along
with its green approaches. This plant has been extensively used in herbal medicine and has various important phytopharmacological properties.
The modern green technological approaches of this plant enhance agricultural productivity when its various nanoparticles are applied in fields that
perform antimicrobial, antipathogenic activities. Nanoparticles serve as carriers for the delivery of drugs and as disease targets in contemporary
medicine. This plant has recently been involved in modern medicine as a threat to cancer, which is a significant accomplishment for modern
medical science. Hence, A. cathartica is an important plant that can be useful to cure various ailments and could be useful in modern science with
its green approaches. We must further investigate this plant's bioactivities to determine the mode of action.
Effect of a fruit and vegetable drink on muscle recovery after resistance exercise
Authors: Pinheiro Maria Hipólito Almeida , Fonseca Luan Pereira , Oliveira Jeann Carlo Gazolla de , Castro Gotardo do Carmo de , Santos-Rezende Vitor Hugo , Gouveia Mariana da Silva , Viveiros Bruna Dias , Martins Eliane Maurício Furtado , Franco Frederico Souzalima Caldoncelli , Ferreira-Júnior João Batista 
Published: December 2022

Objective: To evaluate the effect of fruit and vegetable drink supplementation on muscle recovery after resistance exercise. Methods: 11 men performed two experimental conditions 12 days apart, in a randomized and double-blind manner: 1) Supplementation with Smoothie - drink based on pineapple, mint, sage, ginger, and pomegranate; and 2) Placebo - drink based on artificial pineapple juice. Participants ingested 400 mL of Smoothie or Placebo drinks daily for 9 days, starting one week before performing the exercise (10 sets of 10 unilateral maximum repetitions in leg press 45º). The perceived subjective recovery (PSR), thickness (MT) and soreness (MS) in the anterior thigh muscles, and maximum isometric strength (MIS) were measured before, 24, 48, 72, and 96 h after exercise. Results: There was a reduction in MIS and PSR and an increase in MS 24 h after exercise (p < 0.05). In both situations, MIS returned to baseline values at 72 h (p > 0.05), while PSR and MS returned to baseline values 96 h after exercise. There was no change in MT (p > 0.05). Conclusion: Supplementation with pineapple, mint, sage, ginger, and pomegranate drinks did not accelerate muscle recovery over 96 h after the 45º leg press exercise.
Estimating County-Level Overdose Rates Using Opioid-Related Twitter Data: Interdisciplinary Infodemiology Study
Authors: Cuomo Raphael , Purushothaman Vidya , Calac Alec J , McMann Tiana , Li Zhuoran , Mackey Tim 
Published: December 2022

BackgroundThere were an estimated 100,306 drug overdose deaths between April 2020 and April 2021, a three-quarter increase from the prior 12-month period. There is an approximate 6-month reporting lag for provisional counts of drug overdose deaths from the National Vital Statistics System, and the highest level of geospatial resolution is at the state level. By contrast, public social media data are available close to real-time and are often accessible with precise coordinates.ObjectiveThe purpose of this study is to assess whether county-level overdose mortality burden could be estimated using opioid-related Twitter data.MethodsInternational Classification of Diseases (ICD) codes for poisoning or exposure to overdose at the county level were obtained from CDC WONDER. Demographics were collected from the American Community Survey. The Twitter Application Programming Interface was used to obtain tweets that contained any of the 36 terms with drug names. An unsupervised classification approach was used for clustering tweets. Population-normalized variables and polynomial population-normalized variables were produced. Furthermore, z scores of the Getis Ord Gi clustering statistic were produced, and both these scores and their polynomial counterparts were explored in regression modeling of county-level overdose mortality burden. A series of linear regression models were used for predictive modeling to explore the interpretability of the analytical output.ResultsModeling overdose mortality with normalized demographic variables alone explained only 7.4% of the variability in county-level overdose mortality, whereas this was approximately doubled by the use of specific demographic and Twitter data covariates based on a backward selection approach. The highest adjusted R2 and lowest AIC (Akaike Info Criterion) were obtained for the model with normalized demographic variables, normalized z scores from geospatial analyses, and normalized topic counts (adjusted R2=0.133, AIC=8546.8). The z scores of the Getis Ord Gi statistic appeared to have improved utility over population-normalization alone. In this model, median age, female population, and tweets about web-based drug sales were positively associated with opioid mortality. Asian race and Hispanic ethnicity were significantly negatively associated with county-level burdens of overdose mortality.ConclusionsSocial media data, when transformed using certain statistical approaches, may add utility to the goal of producing closer to real-time county-level estimates of overdose mortality. Prediction of opioid-related outcomes can be advanced to inform prevention and treatment decisions. This interdisciplinary approach can facilitate evidence-based funding decisions for various substance use disorder prevention and treatment programs.
Knowledge of hypertension and its therapy in lay people
Authors: Simatupang Abraham , Sitompul Fransiska , Kurniaty Linggom , Djojosaputro Mulyadi , Lumbantobing Romauli , Silaban Hertina 
Published: December 2022

Hypertension is one of the non-communicable diseases that is becoming a global health problem. Hypertension can be identified by systolic blood pressure of 140 mmHg and diastolic 90 mmHg . Uncontrolled hypertension can lead to complications such as stroke, ischemic heart disease, heart attack, heart failure, kidney failure, blindness, etc. According to Basic Health Research 2018 ( Ris et Kesehatan Dasar 2018/Ris kesdas 2018) the prevalence of hypertension for >18 years old wa s 8.4%, and through measurements taken in health care facilities by 34.1%. Prevalence in the city was 34.4%, in the village was 33.7%, while according to gender 31.3% f or male and 36.9% for female. The study aimed to find out the knowledge and awareness of laypeople on hypertension and its therapy. This was a cross-sectional online study with 11 questions. Respondents were recruited from social media groups. The results showed 5 00 respondents (62.8 % female and 37.2 % male) involved in this study . The most common age range was 21-40 years (36.2 %), followed by 41-55 years (38.2%) , and the least was 56-65 years old (18.4%). Seventy-two percent of respondents did not have hypertension, and 9% said they did not know. Fifty-three percent of respondents knew about the value of high blood pressure, and 89% of the respondents said hypertension should be treated regularly. The most hypertension complications answered by respondents were stroke (40%), heart attack (26%) , and heart failure (16%). Amlodipine was the most mentioned by the respondents, and the second was ACE-inhibitor. However, omeprazole and omega-3 were also mentioned as anti-hypertension. Genetic s and a high salt diet were risk factors that many respondents chose. In conclusi on, the r espondents have a good understanding of hypertension. Information related to behaviour is needed to discontinue the increasing prevalence.
The effects of Curcuma xanthorrhiza rhizome simplicia and Camellia sinensis green tea in a patient with chronic hepatitis B infection: a case report
Authors: Ismail Sjarif , Fikriah Ika , Tandirogang Nataniel , Kosala Khemasili 
Published: December 2022

The hepatitis B virus (HBV) causes acute and chronic liver infections which can be treated by using interferon and antiviral. However, the treatment is relatively expensive. We reported here a case of a patient with chronic hepatitis B who had negative seroconversion without interferon (IFN) and antiviral treatment after herbal consumption. A retrospective investigation showed that the patient consumed Curcuma xanthorrhiza rhizome and Camelia sinensis green tea. These herbs were widely both in vitro and in vivo studied for their effects against HBV infection, although the clinical studies are limited. This case reported the effect of C. xanthorrhiza rhizome and C. sinensis green tea consumption in a patient with chronic hepatitis B. A female patient with chronic hepatisis B infection at the age of 32 y.o. had been taking neuro vitamins regularly for a year before infection detected. She was an asymptomatic patient with normal limits liver function, positive HBsAg and negative anti-Hbs. At the age of 45, she started taking C. xanthorrhiza rhizome simplicia equivalent to 5mg of curcumin twice daily and drinking C. sinensis green tea regularly. Six years later, HBsAg was not detected and her liver function remained within normal limits and Anti-HBs were detected 5 years later. In conclusion, the consumption of C. xanthorrhiza rhizome and C. sinensis green tea can against chronic hepatisis B infection by eliminate HBV dan induce anti-HBs.
CONVIVIALITY AND BECOMINGS WITH-IN DIFFERENCE. MORE-THAN-HUMAN RELATIONSHIPS IN CANDOMBLÉ
Authors: Calvo Daniela 
Published: December 2022

In Candomblé, existence and the continuation of life are dependent on a complex dynamic of interactions involving humans and non-humans (objects, artifacts, the environment, animals, plants, minerals, the ancestors, spiritual beings, forces). It is an ontological monism, based on the concept of àṣẹ, the life force that constitutes life in its manifestations; a conception of human beings as a composition of spiritual and material components (in which ancestors, elements of nature and divine particles participate); ways of communicating and connecting with natural phenomena, the ancestors and the spiritual world; the forms of conceiving of, living with and treating health and disease; and ways of making kin all express a mode of existence, of inhabiting the world and developing along lines of life in which all more-than-human beings participate.
The centrality of water, breath and blood – all of which have the ability to flow inside and outside of the body and from one body to another and are the major expressions of life – in rituals, transmission of knowledge, daily care and social relations, expresses fluidity and networks of connectivity and conviviality, as well as the incompleteness of all beings. Furthermore, the centrality of Èṣù, òrìṣà of crossroads and encounters, which ensures movement, communication and the dynamic balance of forces in the Cosmos and society, is the foundational principle of Candomblé cosmogony.
The current study is based on an ethnographic study carried out at the Àṣe Idasilẹ Ọdẹ of Bàbá Marcelo Monteiro Odearofa, a Candomblé terreiro in Rio de Janeiro, Brazil.
A specific obsidian workplace at the Malice culture settlement in Kraczkowa 31, Podkarpackie Voivodship (southeastern Poland)
Authors: Dębiec Maciej , Pelisiak Andrzej 
Published: December 2022

This paper presents a chipped assemblage from the Malice culture settlement in Kraczkowa 31. Obsidian artefacts dominate in this inventory. The typological structure of obsidian items (small numbers of cores, flakes and blades, and numerous various chips) indicates the existence of a specific workshop where processing of this material occurred.
artista nacional?
Authors: Almeida Gama Víctor , Sugamosto Alexandre 
Published: December 2022

A descoberta dos manuscritos da Clavis Prophetarum (A Chave dos Profetas), documento que era considerado desaparecido há pelo menos trezentos anos e ressurgiu em 2022, reacendeu o interesse na obra do “jesuíta do rei” e em seus escritos considerados fundamentais para “para a história luso-brasileira” 1. No entanto, a realidade é que a obra de Antônio Vieira (1608-1697) tem sido fonte de controvérsia teológica e literária desde que vieram a lume. Por exemplo: uma das teses centrais da Clavis, -tese a respeito da qual nem o próprio Vieira parece ter alimentado convicção ao longo da vida- é a de que estava em gestação o tempo da consumação milenar do “reino de Cristo”. O livro faz parte do que a historiografia convencionou chamar de “Trilogia do Quinto Império”: somam-se ao “Chave dos Profetas”, a carta “Esperanças de Portugal” (“Carta ao Bispo do Japão”), escrita em 1659, e a “História do Futuro”. Em diversos momentos da trilogia, Vieira afirma que esse Quinto Império- aquele que consumará o futuro esperado e sucederá o dos egípcios, assírios, persas e romanos- é o próprio reino de Portugal.
O artigo pretende analisar a carta do Padre Vieira, Esperanças de Portugal, em seus aspectos literário e teológico.
Fabrice Hadjadj, leitor de autores italianos
Authors: Luz Neto João Pedro da , Brandão Bernardo Guadalupe dos Santos Lins 
Published: December 2022

O presente artigo pretende mostrar como o filósofo e ensaísta de sobrenome árabe, origem judia e religião católica Fabrice Hadjadj se utiliza de dois autores italianos, a saber, Dante Alighieri e Lorenzo da Ponte, para aprofundar as suas reflexões sobre a noção de Paraíso. No primeiro caso, Dante fornece pistas para a compreensão de uma noção de Paraíso que ultrapasse as críticas de Friedrich Nietzsche. No segundo, o autor explora o conceito de “redenção”, presente na ópera “Don Giovanni”.
Após a exposição da interpretação do filósofo em cada caso, constatamos que a leitura de Dante promove, para Hadjadj, um deslocamento do paraíso do exterior para o interior e que Don Giovanni explicita, segundo Hadjadj, a dinâmica redentora do Paraíso, à medida em que o convite à máxima felicidade não é fruto de uma conquista pessoal ou do cumprimento de um preceito moral, mas um dom que vem do Alto. Finalmente, constatamos o caráter transdisciplinar da leitura que Hadjadj faz de Da Ponte e Dante, considerando-os como autores cujas obras exprimem realidades profundas que precisam ser desveladas e que podem envolver e auxiliar àqueles que leem o texto contemporaneamente.
PENDAPATAN DAN KESEJAHTERAAN RUMAH TANGGA AGROINDUSTRI TAHU PADA SENTRA INDUSTRI TAHU DI PEKON GADINGREJO KECAMATAN GADINGREJO KABUPATEN PRINGSEWU
Authors: Satria Moch Angga , Adawiyah Rabiatul , Kasymir Eka 
Published: December 2022

This study intends to interprete the income, the level of household welfare of tofu agroindustry owners and to know the factors related to the level of household welfare of tofu agroindustry owners at the tofu industry center, Gadingrejo District, Pringsewu Regency. The research location is in Pekon Gadingrejo, Gadingrejo District, Pringsewu Regency using a census method. There are 15 respondents who own tofu agroindustry in Pekon Gadingrejo. Data analysis uses a descriptive quantitative analysis that includes the level of welfare according to Sajogyo, BPS, World Bank, and ADB as well as Spearman Rank analysis to determine the related factors. The results showed that the household income of tofu agroindustry owners in Pekon Gadingrejo was before the pandemic of IDR32,214,381.20 per month with a percentage of 97,41% of tofu agroindustry businesses, and income from other businesses of 2,59%. Household income during the pandemic was IDR23,273,759.10 per month with a percentage of 96,63% of tofu agroindustry businesses and income from other businesses of 3,37%. The welfare and poverty level of tofu agroindustry households in Pekon Gadingrejo based on Sajogyo's criteria, most of the group is sufficient, based on the standard of BPS, which is 40 % in the poor category, based on the criteria of the World Bank and ADB, which is a poverty rate of 0 %. The factors related to the level of household welfare of the tofu agroindustry are the level of household income and household expenditure. Key words: household, income, tofu, welfare
ANALISIS PENENTUAN HARGA POKOK PRODUKSI, NILAI TAMBAH DAN STRATEGI OPERASIONAL AGROINDUSTRI KOPI LAMPUNG SR DI KOTA BANDAR LAMPUNG
Authors: Sari Nadya Kurnia , Indriani Yaktiworo , Marlina Lina 
Published: December 2022

This study aims to analyze the cost of production, added value, internal and external factors and operational strategies of Lampung SR Coffee Agroindustry. This research is a case study involving respondents of agroindustry owners, employees, and consumers and addition to lecturers of agribusiness and employees at the Department of Industry and Trade of Lampung Province. The data was analyzed quantitative descriptively by cost of goods manufactured and added value and qualitative descriptively by SWOT analysis . The result showed that the production cost of Lampung SR Coffee Agroindustry was IDR45,938/kg to IDR106,856/kg. The added value generated was IDR17,241.75/kg – IDR103,385.89/kg. After knowing the total value of internal factors and externals factor, it was known that the agroindustry was in quadrant I (growth). The strategy that might be implemented was to expand the marketing areas, increase production and carry out by online marketing using promotion and business development by utilizing its strengths. Key words : added value, agroindustry, operational strategy, production cost