bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unimodular Gravity in Covariant Formalism
Authors: Matouš Bohuslav , Klusoň Josef 
Published: July 2023

Abstract
In this short note we study unimodular gravity in Weyl-De Donder formalism. We find corresponding Hamiltonian and study consequence of the unimodular constraint on the conjugate covariant momenta. We also find covariant Hamiltonian for Henneaux-Teitelboim unimodular action and study corresponding equations of motion.
Hybrid Optimization Algorithm for Data Leakage Reduction in Cloud Computing
Authors: Sharma Nikhil Sharma Nikhil , Singh Monika Singh Monika 
Published: July 2023

Abstract
In a Multi cloud system, we can store a large amount of privet data and sensitive information without any proper optimization of the user information. We will be focused on reducing data leakages to every cloud storage provider and provide a better technique for distributed user privet information over different CSPs in a leakage aware manner. The process of an unplanned distribution of data chunks will result in disposing of the essential information while using multiple clouds. To reduce data leakage, the hybrid optimization algorithm is proposed in this research work. The proposed model is implemented in cloud sim and results is analysed in terms of certain parameters.
A Performance Prediction Solution for Modified Hemispherical Solar Still Based on Machine Learning
Authors: Sedik Ahmed , Hamada Mohamed A. , Sharshir Swellam W. , Medhat T. , Ali Manal E. 
Published: July 2023

Abstract
Artificial intelligence has been involved into different research fields. One of the interesting fields is the mechanical engineering field. This research work intends to introduce an alternate prediction approach that can predict the Hemispherical Solar Still (HSS) performance effectively without using an empirical method. The thermal performance of the HSS is predicted using five prediction models including Decision Tree (DT), Random Forest (RF), Gradient Boost (GB), Support Vector Machine (SVM), and K-Nearest Neighbor (KNN), which are performed, assessed, and compared. The proposed prediction models are built using real experimental data that has been recorded. The effective prediction model to be employed in the prediction of the hourly productivity and the instantaneous efficiency of the HSS is determined using five statistical error values. The comprehensive comparative analysis that was carried out demonstrates that, as compared to other models, the Decision Tree model may be used to estimate the thermal performance of solar stills without the need for additional experiments, saving money, effort, and time as its R2 and EVS values were near to one and the other statistical values (MSE, NAE, and Median Absolut Error) were very small. According to the results of the experiment, the HSS has an average hourly productivity of 0.478 L/m2 with the daily water production of 0.477, 0.465, 0.476, 0.477 L/m2 day for the proposed DT, SVM, RF, KNN and GB models, respectively. In addition, an average instantaneous efficiency of 45.199% with daily efficiency 45.188, 46.374, 46.375. 44.794 and 45.2 % for DT, SVM, RF, KNN and GB, respectively. Therefore, the proposed models appear a superior performance prior to performance estimation of HSS and can be considered as an efficient solution for this issue.
Dislocation of Implantable Collamer Phakic Lens after Blunt Trauma: A Case Report
Authors: Zhong Xin , Li Tong , Du Yali 
Published: July 2023

Abstract
Background
Implantable Collamer Lens (ICL) surgery is a beneficial option for correcting high myopia due to its stable long-term outcomes and improved night vision with a wider optical zone. The reversible procedure is particularly useful for high myopia correction. Traumatic displacement of ICL is rare but carries the potential to develop vision-threatening complication. Timely intervention with thoroughly consideration of surgical planning remains challenging. We present a rare case of traumatic dislocation and pupillary capture of the ICL after blunt trauma, in which the patient underwent surgical intervention of ICL repositioning.
Case presentation
A 44-year-old man presented with a loss of vision in his left eye, accompanied by photophobia and pain, after receiving blunt ocular trauma from a fist one hour ago. This patient had undergone bilateral ICL implantation for high myopia four years prior to presentation. On examination, one footplate of the ICL was entrapped in the pupillary, located on the nasal side of the iris. The patient showed 4+ red blood cells and Grade I hyphema in the anterior chamber of his left eye, along with moderate vitreous hemorrhage and slight angle recession at the 9 o'clock position. The dislocation and pupillary capture of the ICL were surgically corrected to a horizontal position under topical anesthesia one week after the injury, resulting in a stable location in his left eye with stable postoperative vault.
Conclusion
Traumatic ICL dislocation is rare but poses the risk of long-term complications. Prompt intervention can lessen the chances of complications in difficult cases. Thorough examination is vital to quickly identify and diagnose the dislocation, which may mitigate potential vision-threatening complications.
Introducing DeReKoGram: A novel frequency dataset with lemma and part- of-speech information for German
Authors: Wolfer Sascha , Koplenig Alexander , Kupietz Marc , Müller-Spitzer Carolin 
Published: July 2023

Abstract
We introduce DeReKoGram, a novel frequency dataset containing lemma and part-of-speech (POS) information for 1-, 2-, and 3-grams from the German Reference Corpus. The dataset contains information based on a corpus of 43.2 billion tokens and is divided into 16 parts based on 16 corpus folds. We describe how the dataset was created and structured. By evaluating the distribution over the 16 folds, we show that it is possible to work with a subset of the folds in many use cases (e.g. to save computational resources). In a case study, we investigate the growth of the vocabulary (as well as the number of hapax legomena) as more and more folds are included into the analysis. We cross-combine this with several cleaning stages of the dataset. We also give some guidance in the form of Python, R and Stata markdown scripts on how to work with the resource.
Validation study for sentinel lymph node biopsy in intraoral squamous cell cancer.
Authors: Illarramendi Imanol Zubiate , Font Carlos Ramos , Iglesias Fernando Monsalve , Lara Ildefonso Martínez 
Published: July 2023

Abstract
Purpose
The objective of the study was the validation of the sentinel lymph node biopsy technique for intraoral squamous cell cancer.
Methods
A descriptive study of the patients threated with a sentinel lymph node biopsy for intraoral squamous cell cancer during the year 2021 at the Virgen de las Nieves University Hospital in Granada was done. As the technique was being validated, homolateral elective neck dissection of levels IA, IB, IIA, IIB, III and IV was performed in all patients.
Results
The study presents 31 patients (17 men and 14 women) with early-stage intraoral squamous cell carcinoma (cT1/cT2 N0), obtaining 32.6% (10) of sentinel nodes positive for squamous cell carcinoma. The sensitivity was 90% and the specificity 100%. The most frequent location was the left lingual lateral border, with the migration of the radiotracer unilaterally. The mean hospital stay was 4.7 days and the mean surgical time was 237.7 minutes. There were two cases of postoperative cervical hematoma and two cases of shoulder pain syndrome, which improved with physiotherapy.
Conclusion
We conclude that it is a useful technique for detecting occult metastases in the early stage (T1/T2 N0) intraoral squamous cell cancer, avoiding unnecessary neck dissections, reducing morbidity and hospital costs, without having a negative impact on patient survival
Risk factors and nomogram predictive model of surgical site infection in closed pilon fractures
Authors: Ke Chenrong , Dong Xiaoyu , Xiang Guangheng , Zhu Juanjuan 
Published: July 2023

Abstract
Objectives
In this study, we try to investigate the risk factors of postoperative surgical site infection (SSI) in closed pilon fractures and establish a nomogram prediction model.
Methods
From January 2012 to June 2021, 516 closed pilon fracture patients were the subjects of this study. Of these, 387 patients were randomly assigned to the development group and 129 patients were assigned to the validation group (3:1). By univariate and multivariate Cox analysis, we identified independent risk factors for postoperative SSI after Pilon fracture. We established a nomogram model and used receiver operating characteristic (ROC) and calibration chart to evaluate its discriminant and calibration.
Results
SSI occurred in 71 patients in the development group and 23 patients in the validation group. Ultimately, age, preoperative blood sugar, operative time, Tscherne and fracture classification were identified as independent risk factors for SSI. The AUC values for SSI of the development and validation group were 0.898 and 0.880, and the P value of the Hosmer-Lemeshow test was 0.125. We established a nomogram prediction model based on age, preoperative blood sugar, operative time, Tscherne and fracture classification.
Conclusion
Our nomogram model had good discrimination and calibration power, so it could be used to predict SSI risk in patients with pilon fracture.
One-pot synthesis of CdTe/ZnS quantum dots and their physico- chemical characterization
Authors: Aguilar Gabriela Travieso , Mijares Maykel Márquez , Solís-Pomar Francisco , Gutiérrez-Lazos C. D. , Pérez-Tijerina Eduardo G. , Cruz Abel Fundora 
Published: July 2023

Abstract
A known property of QDs is their characteristic luminescence, which would make it possible to detect different types of cancers after being functionalized with some type of biological molecule. For this reason, in the present investigation a methodological analysis of the physicochemical characteristics of the CdTe/ZnS core/shell QDs was carried out, using techniques such as UV-Vis absorbance, Molecular Fluorescence, FT-IR, DLS and Zeta Potential that allowed to verify the photoluminescent effectiveness of these semiconductor nanocrystals as an alternative to conventional techniques currently used for the detection of specific cancers smaller than 1cm. The study consisted of theoretically determining the bandgap energy, the size of the nanocrystals and the molar absorptivity from the wavelength value for the maximum intensity of the excitonic peak. It was also possible to verify the maximum intensity for each sample and thus evaluate its photoluminescent response, as well as it was possible to determine the charge distribution, the hydrodynamic size and the surface composition of each quantum dot. The results obtained correspond to what has been reported in the literature, which makes them good candidates for the detection of cancer in precancerous stages.
CDC73 promotes breast cancer through impairing MAPK1 ubiquitination and activating mTOR signaling pathway
Authors: Zhang Haige , Tang Yu , Gao Ya , Du Mingming , Pan Erhu , Pei Fangfang , Sun Mingliang , Sang Guopeng , Liu Chang , Ruan Zhifan , Pan Yubo , Zhang Xiaozhi , Pei Jing 
Published: July 2023

Abstract
Breast cancer is the most common global malignancy and the leading cause of cancer deaths. CDC73 (Human cell division cycle 73), a nuclear protein, participates transcription regulation and its functions are controversial in malignancies. CDC73 has been reported to be upregulated in breast cancer. The underlying mechanism, however, has not been fully illuminated. In breast cancer, CDC73 could promote the proliferation of tumor cells, and the expression of CDC73 was related to poor prognosis in patients. Here, we found that CBL, an E3 ubiquitin ligase, could interact with CDC73 and promote MAPK1 ubiquitination and degradation of this protein. In addition, silencing MAPK1 led to a suppression of breast cancer cell growth in vitro and in vivo, and even abolished the promoting effects of CDC73 overexpression. We also found that mTOR pathway played a role in CDC73-mediated breast cancer. mTOR pathway inhibitor reversed cell phenotypes induced by CDC73 overexpression. Our study revealed the underlying mechanism of CDC73 in breast cancer: it promoted MAPK1 ubiquitination and degradation so that affected MAPK1 level and subsequently led to tumor progression, providing a novel therapeutic strategy to combat cancer.
Influences of composite additives and technological parameters on the microstructure and properties of electrolytic copper foil
Authors: Liu Jing-pei , Sun Wan-chang , Bai Zhong-bo , Liu Er-yong , Cai Hui , Zhang Jing-li , Tian Sha-sha , Zhang Cong-xiao , Xu Yi-fan , Zhou Meng-ran , Zhang Bo 
Published: July 2023

Abstract
In this paper, the additives consisting of bis-(3-sulfopropyl)-disulfide (SPS), hydroxyethylcellulose (HEC) and collagen additive compounding, are proposed to fabricate ultra-thin copper foils with low roughness on titanium substrates. The effect of the deposition time, temperature and voltage on the morphology and roughness of electrolytic copper foil is explored. The results show that the deposited layers obtained at the electrodeposition time of 3 min, the electrolyte temperature of 50°C and the output voltage of 2.5 V exhibit small grain size and good adhesion to the substrate. Meanwhile, the effects of the two-component additive and the three-component additive on the microstructures, surface roughness and electrochemical behavior of copper foils are studied. Scanning electron microscopy images reveal that copper foils prepared by simultaneous introduction of 0.06 g/L SPS and 0.08 g/L collagen possess a dense and homogeneous structure with the smallest grain size (6.21 µm) and the lowest roughness (Rz = 2.30 µm), which is diminished by 26.17%. The electrodeposition principle and the action mechanism of additives suggest that the antagonistic interaction between SPS and HEC hinders the preferential adsorption of the additive at the surface protrusions and reduces the refinement ability of SPS additive. Benefiting from the synergistic effect of the SPS and collagen additive, the electrochemical properties of the copper foil are improved. Besides, the levels of three-component additives are determined by orthogonal experiments as 0.06 g/L SPS, 0.12 g/L HEC and 0.10 g/L collagen.
Wheat Allergy and its Association with COVID-19: Prevalence, Symptoms, and Predictive Analysis in Post-COVID-19 Patients
Authors: Yousif Maitham Ghaly 
Published: July 2023

Abstract

Wheat allergy is a common food allergy that can develop in individuals after contracting the COVID-19 virus. This research aims to provide comprehensive information regarding the prevalence of wheat allergy among post-COVID-19 patients, the associated symptoms, and the use of machine learning techniques for predicting wheat allergy development. The study was conducted on a sample of 560 post-COVID-19 patients across different age groups and genders. It was found that 18% of males and 16% of females developed wheat allergy after contracting COVID-19. Various symptoms of wheat allergy were observed among the patients, including abdominal pain, diarrhea, cough, wheezing, and itching. The results suggest a potential relationship between the severity of COVID-19 and the development of wheat allergy. Patients who experienced severe and critical cases of COVID-19 were found to be more susceptible to developing wheat allergy at a higher rate (43.8%, 46.2%). The findings also indicate that age, gender, and pre-existing allergies may play roles in the development of wheat allergy. Furthermore, machine learning techniques were employed to predict wheat allergy development. The results demonstrated that factors such as age, gender, and pre-existing allergies could be used to predict wheat allergy development with reasonable accuracy. This study sheds light on the association between wheat allergy and COVID-19, providing valuable insights into the prevalence, symptoms, and predictive analysis of wheat allergy in this specific population. Further research and validation are warranted to enhance our understanding of this association and its clinical implications.
Evaluating Strategic Implementation and Sustaining Therapeutic Lifestyle Changes in Sultanate of Oman: The Impact of COVID-19 pandemic
Authors: Fattah Fadi Abdel , AL_Alawi Abrar , Salah Mohammed , Alwishahi Maryam 
Published: July 2023

Abstract
Purpose – This study evaluates the strategic implementation and sustainability of therapeutic lifestyle changes (TLCs) in the Sultanate of Oman in response to the prevalence of non-communicable diseases (NCDs) and the challenges posed by the COVID-19 pandemic. Additionally, the study examines the effectiveness of pharmacological measures used to manage NCDs during the pandemic.
Design/methodology/approach – Drawing from an extensive literature review, a conceptual model is developed, highlighting various external factors influencing the management of NCDs. The researchers adopt a quantitative research approach, collecting a representative sample of 412 participants from Oman. Statistical analysis is conducted using SPSS and PLS software to test the proposed hypotheses.
Findings – The results reveal significant direct effects between therapeutic lifestyle changes, the healthcare system, health behaviour, and NCDs management during the COVID-19 pandemic. Furthermore, health behaviour is shown to mediate the relationship between therapeutic lifestyle changes and NCDs management, as well as the relationship between the healthcare system and NCDs management under pandemic conditions.
Practical implications – The findings suggest that the implementation of therapeutic lifestyle changes should be supported by the healthcare system and community involvement. The development of improved assessment tools to evaluate the impact of these strategies can aid in tailoring TLC interventions to the specific characteristics of the population. Moreover, effectively addressing the prevalence of NCDs in Oman requires policy changes and improvements in the healthcare system.
Originality/value – This study presents a unique conceptual model that contributes to the existing literature on NCDs and specifically addresses the challenges imposed by the COVID-19 pandemic. The research results and recommendations provided advance the role of TLCs in managing NCDs and contribute to filling the knowledge gap in this area.
Evaluation of Trans Anal Endorectal Pull-Through Outcomes in Hirschsprung Disease in Different Age and Gender Groups: A Comprehensive Systematic Review
Authors: Meidansar Farshid Ghasemi , Moradi Mohammad , Nabipoorashrafi Seyed Ali , Nasiri Seyyed Javad , Chavoshi Tahereh , Aldraji Mohammad , Jahangiri Fariba 
Published: July 2023

Abstract
Introduction;
The timing of endorectal pull-through for Hirschsprung’s disease (HD) is controversial. Early endorectal pull-through avoids the occurrence of preoperative enterocolitis. However, delayed pull-through (≥31 days) enables postnatal maturation of the anal canal and sphincter complex. The aim of this study was to identify the best age to perform trans-anal pull-through according to the literature.
Methods and Materials;
This was a comprehensive systematic review. All published articles from 2010 to 2022 were searched through Web of Science, Ovid Medline, PubMed, CINAHIL, and Embase databases, using the keywords Hirschsprung's disease, delayed or early treatment, trans-anal Pull-Through surgery, age, sex or gender, complications and outcomes. Articles that met the inclusion criteria along with good to fair quality according to the Newcastle-Ottawa quality assessment and low bias score in the Cochran collaboration tool were reviewed.
Results;
Sixteen studies were eligible to be reviewed. The overall results of this study showed that due to more common short-term complications at neonatal period and lower contrast enema diagnostic accuracy in determining the transition zone, postponing surgery until the child is several months old seems to be a reasonable decision. There was also no difference in terms of complications and outcomes of trans-anal Pull-Through surgery between females and males.
Conclusion;
it is not recommended to delay surgery too much for ages over 1 year. Ages between 3 and 12 months can be a good time to take interventional treatment for Hirschsprung's disease.
Circulating PCSK9 as a prognostic biomarker of cardiovascular events in individuals with type 2 diabetes: evidence from a 16.8-year follow-up study
Authors: Ruscica Massimiliano , Macchi Chiara , Giuliani Angelica , Rizzuto Alessandra Stefania , Ramini Deborah , Sbriscia Matilde , Carugo Stefano , Bonfigli Anna Rita , Corsini Alberto , Olivieri Fabiola , Sabbatinelli Jacopo 
Published: July 2023

Abstract
Background.
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and mortality, being twofold to fourfold more common in patients with type 2 diabetes mellitus (T2DM) than in individuals without diabetes. However, despite this decade-old knowledge, particularly challenging remains the identification of a specific prognostic risk biomarker.
Methods.
Taking advantage of a large sample of Caucasian patients (n = 568) with a diagnosis of T2DM followed for a median of 16.8 years, the present study was aimed at testing the hypothesis that fasting serum proprotein convertase subtilisin/kexin type 9 (PCSK9) levels could be prognostic for major cardiovascular events (MACE) and all-cause mortality.
Results.
Median levels of PCSK9 were 259.8 ng/mL, being higher in women compared to men and increasing even more in the presence of a complication (e.g., diabetic kidney disease). PCSK9 positively correlated with markers of blood glucose homeostasis (e.g., HbA1c, fasting insulin and HOMA-IR) and the atherogenic lipid profile (e.g., non-HDL-C, apoB and remnant cholesterol). Serum PCSK9 predicted new-onset of MACE, either fatal or non-fatal, only in women (Odd Ratio: 2.26, 95% CI 1.12–4.58) and all-cause mortality only in men (Hazard Ratio: 1.79 [1.13–2.82]).
Conclusions.
Considering that up to two-thirds of individuals with T2DM develop ASCVD in their lifetime, the assessment of circulating PCSK9 levels can be envisioned within the context of a biomarker-based strategy of risk stratification. However, the sex difference we found highlight an urgent need to develop sex-specific risk assessment strategies.
Trial registration
It is a retrospective study