bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular markers and phenotypic identification reveal the genetic diversity and structure of four local tea plant populations in China
Authors: Wang Zhihui , Peng Hua , Yue Cuinan , Ye Chuan , Li Wenjin , Yang Puxiang 
Published: April 2023

Abstract
The local tea plant population resources are rich in genetic variation, which is the natural treasure house of tea genes and the main source of breeding excellent tea cultivars. However, the genetic information of most local tea plant populations is still unknown. In this study, the genetic diversity and population structure of four main local tea plant populations in Jiangxi Province of China were explored by combining phenotypic characters identification and simple sequence repeats (SSR), and the loci associated with phenotypic characters were screened. The results of genetic diversity analysis of phenotype and SSR were consistent. It was found that the genetic diversity of population species was higher than that of wild species. The order of genetic diversity index of the four tea plant populations was Wuyuan > Fuliang > Suichuan > Ningdu. The single-plants of each population were heterozygotes, and Wuyuan had the highest heterozygosity. The clustering results of phenotypes and SSR on tea plant populations were not completely consistent. SSR could more effectively distinguish tea plant populations. Four tea populations could be clustered into three groups. Further analysis found that the geographical location of tea population distribution would affect its gene exchange. In addition, 9 SSR loci were screened and were significantly associated with 9 phenotypic characters (P < 0.01), and the interpretation rate of phenotypic variation ranged from 6.94–33.90%. These phenotypic characters related to the yield and mechanical harvest of tea varieties.
Staff experiences of the use of virtual consultations in Non-Surgical Oncology Systemic Anti-Cancer Therapy services
Authors: Warnock Clare , Pelton Jeremy , Hilton Anne 
Published: April 2023

Abstract
Purpose
In response to the COVID-19 pandemic, virtual consultations were introduced rapidly across cancer services. This created a particular set of challenges for Systemic Anticancer Therapy services, where patients have frequent, regular appointments to support decision-making regarding treatment. This study explores the experiences of staff who provide these consultations to understand the implications for patients, staff and services.
Methods
A mixed methods approach was utilised using electronic surveys containing open text and structured responses and a focus group. The survey was sent to all staff in a regional cancer centre who carried out consultations with patients receiving Systemic Anticancer Therapy. Data collection took place between October 2020 and January 2021. Open text responses were analysed using framework techniques.
Results
33 medical, nursing and pharmacy staff completed the survey and 21 attended the focus group. Staff experiences were described within a framework of risk, loss and gain. Virtual consultations had clinical consequences for the accuracy of assessments and communication with patients. Criteria for using virtual or in-person appointments were identified along with organisational systems and processes that influenced effectiveness and safety. Concerns were raised regarding role satisfaction and use of clinical skills.
Conclusion
The study provides new insights into the experiences and concerns of staff associated with virtual appointments. The primary purpose of consultation in Systemic Anticancer Therapy services is to support decision-making regarding treatment and the study identified obstacles to achieving this alongside possible criteria for determining when in-person or virtual consultations may be appropriate.
Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma
Authors: ASSONI AMANDA FARIA , Giove Thiago , Wardenaar René , Ferreira Raiane , Jandrey Elisa , Novaes Gabriela , Granha Isabela , Bakker Petra , Kaid Carolini , Zatz Mayana , Foijer Floris , Okamoto Oswaldo Keith 
Published: April 2023

Abstract
Vesicle-associated membrane protein-associated protein B/C (VAPB) has been widely studied in neurodegenerative diseases such as ALS, but little is known about its role in cancer. Medulloblastoma is a common brain malignancy in children and arises from undifferentiated cells during neuronal development. Therefore, medulloblastoma is an interesting model to investigate the possible relationship between VAPB and tumorigenesis. Here we demonstrate that high VAPB expression in medulloblastoma correlates with decreased overall patient survival. Consistent with this clinical correlation, we find that VAPB is required for normal proliferation rates of medulloblastoma cells in vitro and in vivo. Knockout of VAPB impaired cell cycle progression and arrested cells in G0/G1 partially due to a functional interaction with the Ephrin Receptor A4 (EPHA4). Furthermore, transcript levels of WNT-related proteins were decreased in the VAPBKO. We conclude that VAPB is required for proliferation of medulloblastoma cells, thus revealing VAPB as a potential therapeutic target for medulloblastoma treatment.
Improvement of Grain-Yield under Drought Stress and Blast resistance in popular upland rice variety Nagina-22 using Marker Assisted Selection
Authors: Mukherjee Mitadru , Behera Lambodar , Yadav Manoj Kumar , Mahadani Pradosh , Baksh Sk Yasin , Donde Ravindra , Patel Hitendra Kumar , Dash Sushanta Kumar 
Published: April 2023

AbstractDrought and blast disease are the two major abiotic and biotic factors that severely reduce grain-yield (GY) of rice in rainfed-upland. Reproductive stage drought stress (RSDS) along with blast account for > 80% yield loss in rice. Identification of molecular markers for QTLs/genes (GY under RSDS and blast resistance) has opened up new avenues for developing new rice varieties with enhanced resistant/tolerant to these stresses. The current study focussed on introgression of QTL for GY under RSDS (qDTY12.1) and blast resistance genePi9into an upland rice variety Nagina-22 (N-22). Foreground selection was carried out using previously reported markers corresponding to the QTL/gene. Background selection was carried out using 48 uniformly distributed SSRs. Finally, 27 BC2F3lines (BLs), homozygous forqDTY12.1andPi9were identified with background recovery of 87.5- 93.75%. These BLs were categorised into “tall” and “short” groups based on their plant height. Screening for blast resistance showed that all the BLs were highly resistant to blast [Standard Evaluation System (SES): 2–3], unlike the recurrent parent N-22 (SES = 6), which was susceptible. Similarly, these BLs were significantly tolerant to drought in comparison to N-22 (average yield advantage of 705kg/ha over N-22). Study of genetic parameters showed that five traits, namely, GY, DTF, PH, FGPP and SF% recorded high H2values (> 60%) along with high GAM values (> 20%) (stress and non-stress), thereby strongly indicating the effectiveness of direct selection of these traits under contrasting moisture regimes. Correlation analysis indicated that DTF recorded positive and negative correlation with GY under non-stress and drought, respectively. Additionally, GY was positively correlated with PH, FGPP and SF%. Thus, plants having high FGPP, high SF% with short DTF and moderate PH may be selected for higher grain yield under RSDS. Thus, based on these criteria, the “short” BLs were found to be most suitable for farmer’s field and further selected for varietal trials.
IgG4 inflammatory pseudotumor mimicking primary lung cancer
Authors: Seip Tomás , Calderón Novoa Francisco , Valeo Chulvi Melina Paula , Smith David , Dietrich Agustín 
Published: April 2023

Introduction
IgG4 related disease (IgG4-RTD) is an infrequent disease with possible multiple organ involvement. It is characteristic to find inflammatory nodules with IgG4 positive plasma cell infiltration, storiform fibrosis and obliterative phlebitis. We present a patient with an inflammatory pseudotumor in the right upper lobe, mimicking a primary lung tumor.

Case report
Our patient, a 48-year old heavy smoker (25 pack/year) with no relevant medical background, referred chest pain, non-productive cough and sporadic nightly fever. Image findings revealed a mass in the right upper lobe, with increased SUV in PET-scan, and mediastinal lymphadenopathies. Primary lung tumor was suspected and right upper lobectomy was performed. Due to absence of cellular atypia and the intense plasmacytic activity in the lesion, immunohistochemical analysis was performed: abundant IgG4 plasma cells were identified, with a IgG4/IgG relation of 74%. Diagnosis of IgG4- inflammatory pseudotumor was made.

Discussion
After an extensive bibliographic review, we found just one similar case reported with an IgG4-lung pseudotumor without systemic disease.
Due to the broad spectrum of clinical features of IgG4-RTD, and the potential multiple organ involvement, it is hard to find a classification and diagnostic criteria with high sensitivity and specificity, nevertheless they can be useful in clinical practice.

Conclusion
There are several benign inflammatory diseases which can mimic a primary lung tumor. Although incidence is low, IgG4 pseudotumor should be considered as a differential diagnosis in the absence of malignancy.
Apprendre l’anatomie radiographique en présentiel ou en ligne ? Une étude randomisée contrôlée
Authors: Hontoir Fanny , Simon Vincent , De Raeve Yves , Dumortier Laurence , Dugdale Alex , Vandeweerd Jean-Michel 
Published: April 2023

RésuméL’enseignement de l’anatomie repose sur diverses techniques: les cours, les dissections, les modèles 3D ou encore les supports en ligne. Ces derniers sont généralement considérés comme des moyens d’apprentissage complémentaires. Cette étude vise à comparer les performances des étudiants vétérinaires (N=83) en anatomie radiographique (radioanatomie) après un apprentissage en ligne ou conventionnel, et de voir dans quelle mesure ces méthodes sont interchangeables. Trois stratégies sont comparées : apprentissage en ligne exclusif, apprentissage en ligne avec des os de chevaux, apprentissage sur radiographies conventionnelles avec des os de chevaux. Les performances au test de rotation mentale et au test de connaissance en radioanatomie sont similaires entre les 3 groupes à la base, lors du test préliminaire. Après l’apprentissage (test final), les scores de rotation mentale et de radioanatomie augment significativement de 6.7/40 points (CI : 5.2–8.2; p < .001) et de 5.1/20 points (CI: 4.3–5.9; p< .001). Il n’y a pas de différence entre les groupes pour les scores de rotation mentale et de radioanatomie après l’apprentissage. Le score de rotation mentale est influencé par le genre, et significativement plus élevé chez les hommes que chez les femmes au test préliminaire (M= 23.0, SD = 8.8 vs. M= 16.5, SD= 6.9; p= .001) et au test final (M= 32.1, SD= 5.5 vs. M= 22.7, SD= 8.6; p< .001). Les performances en radioanatomie ne sont pas influencées par le genre. Ces résultats suggèrent que l’enseignement de la radioanatomie peut être réalisé en présentiel avec des radiographies conventionnelles ou en ligne. Cette interchangeabilité entre apprentissage en présentiel et en distanciel est intéressante au regard des impératifs liés aux crises sanitaires, et des besoins d’adaptation rapide en distanciel.This translation was provided by the authors. To view the original article visit: https://doi.org/10.3138/jvme-2021-0153
Mekanisme Corporate Governance dan Corporate Social Responsibility terhadap Tax Avoidance pada Perusahaan Sektor Pertambangan Batu Bara
Authors: Kirana Alifia Syahdarani , Sundari Siti 
Published: April 2023

This study aims to empirically examine the effect of corporate governance mechanisms as proxied by institutional ownership, independent commissioners, and audit committees as well as the implementation of corporate social responsibility on tax avoidance. This research method is descriptive communicative. The research was conducted on coal mining sector companies listed on the IDX for the 2017-2019 period. The research data used is secondary data obtained from the annual report. The research sample is 66 annual reports from 22 coal mining sector companies. The research data was processed and analyzed using SPSS 25 software. The data analysis method used descriptive statistics and multiple linear regression. The results showed, a) the t-value of institutional ownership was 1.023 with a significance value of 0.310>0.05; b) the t value of the independent board of commissioners is 0.527 with a significance value of 0.600>0.05; c) the audit committee t value is 0.213 with a significance value of 0.832>0.05; d) the t value of CSR is negative at -0.265 with a significance value of 0.792>0.05. In conclusion, the corporate governance mechanism which is proxied by institutional ownership, independent board of commissioners, and audit committee as well as corporate social responsibility does not contribute to tax avoidance in coal mining sector companies listed on the IDX.

Keywords: Corporate Governance, Corporate Social Responsibility, Independent Board of Commissioners, Institutional Ownership, Audit Committee
FORECASTING THE EXCHANGE RATE OF THE UKRAINIAN HRYVNIA USING MACHINE LEARNING METHODS
Authors: Pryimak Vasyl , Bartkiv Bohdan , Holubnyk Olga 
Published: April 2023

This article describes the concept of currency exchange rate and the typology of various factors that influence it. A multifactor regression model was constructed to investigate the influence of factors on the exchange rate of the Ukrainian hryvnia and to forecast the dynamics of this rate based on the studied factors using Data Science technologies.
The purpose of this work is to study the peculiarities of the formation of the exchange rate of the Ukrainian hryvnia, the characteristics of the influence of various external factors on this rate, and the creation of an effective forecasting model of the Ukrainian national currency rate, based on a certain number of fundamental financial and economic factors that influence this rate.
Macroeconomic indicators that theoretically have an impact on the dynamics of the currency exchange rate were chosen to build the model. Data on the exchange rate of the Ukrainian hryvnia to the US dollar and economic indicators for selected factors were collected from 2010 to September 2022. During the implementation of the task, the collected data was processed, brought into a uniform form, and normalized. Machine learning methods were used for regression modeling, specifically the XGBoost gradient boosting method.
As a result, a retrospective forecast of the Ukrainian hryvnia exchange rate was obtained, based on factor variables, and an estimate of the impact of each selected feature on the currency exchange rate was calculated. The scientific novelty of this work lies in the application of modern machine learning methods and technologies for the analysis, modeling, and forecasting of the exchange rate of the Ukrainian national currency.
The practical significance of this article lies in the possibility of using the proposed approaches to forecasting the exchange rate of the Ukrainian hryvnia with the use of machine learning methods by all interested parties, including financial institutions of Ukraine, to achieve stability of the national currency, which in turn will affect the development of the national economy as a whole and the welfare of the population of the country.
Real-time changes in brain activity during tibial nerve stimulation for overactive bladder: Evidence from functional near-infrared spectroscopy hype scanning
Authors: Li Xunhua , Fang Rui , Liao Limin , Li Xing 
Published: April 2023

PurposeTo use functional near-infrared spectroscopy (fNIRS) to identify changes in brain activity during tibial nerve stimulation (TNS) in patients with overactive bladder (OAB) responsive to therapy.MethodsEighteen patients with refractory idiopathic OAB patients were recruited consecutively for this pilot study. At baseline, all patients completed 3 days voiding diary, Quality-of-Life score, Perception-of-Bladder-Condition, and Overactive-Bladder-Symptom score. Then 4 region-of-interest (ROI) fNIRS scans with 3 blocks were conducted for each patient. The block design was used: 60 s each for the task and rest periods and 3 to 5 repetitions of each period. A total of 360 s of data were collected. During the task period, patients used transcutaneous tibial nerve stimulation (TTNS) of 20-Hz frequency and a 0.2-millisecond pulse width and 30-milliamp stimulatory current to complete the experiment. The initial scan was obtained with a sham stimulation with an empty bladder, and a second was obtained with a verum stimulation with an empty bladder. Patients were given water till strong desire to void, and the third fNIRS scan with a verum stimulation was performed. The patients then needed to urinate since they could not tolerate the SDV condition for a long time. After a period of rest, the patients then were given water until they exhibited SDV state. The fourth scan with sham fNIRS scan in the SDV state was performed. NIRS_KIT software was used to analyze prefrontal activity, corrected by false discovery rate (FDR, p &lt; 0.05). Statistical analyses were performed using GraphPad Prism software; p &lt; 0.05 was considered significant.ResultsTTNS treatment was successful in 16 OAB patients and unsuccessful in 2. The 3 days voiding diary, Quality-of-Life score, Perception-of-Bladder-Condition, and Overactive-Bladder-Symptom score were significantly improved after TNS in the successfully treated group but not in the unsuccessfully treated group. The dorsolateral prefrontal cortex (DLPFC) (BA 9, Chapters 25 and 26) and the frontopolar area (FA) (BA 10, Chapters 35, 45, and 46) were significantly activated during TNS treatment with an empty bladder rather than with an SDV. Compared with the successfully treated group, the unsuccessfully treated group did not achieve statistical significance with an empty bladder and an SDV state.ConclusionfNIRS confirms that TNS influences brain activity in patients with OAB who respond to therapy. That may be the central mechanism of action of TNS.
Facies associations and depositional environments of a mixed siliciclastic-carbonate marginal marine succession: The Lower Carnian (Upper Triassic) middle Charlie Lake Formation, Kobes-Blueberry area, British Columbia, Canada
Authors: Booker Simone , Hubbard Stephen , Rommens Chelsea , Zonneveld John-Paul 
Published: April 2023

AbstractThe Upper Triassic (Carnian) Charlie Lake Formation in northeastern British Columbia, Canada is a heterolithic mixed siliciclastic-carbonate succession of dolomite dolomitic siltstone, well-sorted sandstone, bioclastic sandstone, and anhydrite. This succession is unusual in that it records the only significant non-marine interval in the Triassic of the Western Canadian Sedimentary Basin. In the Kobes-Altares-Blueberry area, moderately abundant core are available through the middle members of the Charlie Lake Formation. All available core were analyzed in order to interpret the depositional setting of constituent members and identify reservoir quality lithofacies and horizons.The middle Charlie Lake Formation in the Kobes-Altares-Blueberry area was deposited in an arid coastal setting. Sixteen lithofacies were identified and placed in three lithofacies assemblages and the latter characterize three depositional settings: coastal salina/playa, aeolian dune, and proximal marine ramps. The coastal salina/playa lithofacies assemblage is heterolithic, and is dominated by dolomitic and anhydritic facies. Depositional subenvironments include intertidal flat, ephemeral lagoon, shore proximal ephemeral lake, sabkha and supratidal paleosol. Potential reservoir lithofacies in this assemblage includes peloidal to stromatolitic dolomitic siltstone deposited in lagoonal and intertidal flat settings. The aeolian dune lithofacies assemblage preserves the movement of small, shore-proximal dunes and associated interdune successions. Well-sorted, fine-grained sandstone beds comprise the best reservoir lithofacies in this assemblage. The proximal marine ramp facies assemblage records several marine transgressions that punctuate the dominantly nonmarine/marginal marine Charlie Lake Formation. Bioclastic packstone, bioclastic sandstone and peloidal dolomitic siltstone to sandstone beds, all exhibit good porosity and are potential hydrocarbon reservoir units within this lithofacies assemblage.
Preliminary Emotional User Experience Model for Mobile Augmented Reality Application Design: A Kansei Engineering Approach
Authors: Nik Ahmad Nik Azlina , Abdullah Munaisyah , Mohd Lokman Anitawati , Suhaimi Ahmad Iqbal Hakim 
Published: April 2023

The user experience, often known as UX, is the key factor in determining a product success and increase user’s acquisition. However, this field of research lacks conceptual and practical models to follow when designing pervasive technologies such as mobile augmented reality (MAR). To convey a pleasant UX, it is necessary to identify the contributing factor and the components that influence the enhancement of the MAR design. The findings of the study indicated that emotions are the main factor that drives the user’s perception and hence, their choice and pleasure. This paper presents a preliminary model for designing an emotional UX mobile augmented reality application with the use of Kansei engineering approach. Ultimately, this model will provide insight into the design fundamentals that influence the user experiences. The outcomes of this study will assist researchers and designers in shaping the emotional user experience design.
Influence of Music Industry on Fashion in Uganda
Authors: Opio Nasiche 
Published: April 2023

Purpose: The study sought to analyze influence of music industry on fashion in Uganda
Materials and Methodology: The study adopted a desktop methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library.
Findings: The results show that artists used expensive apparels to attract increased attention and following particularly online fan base. The style of fashion was determined by market demands. More than 30% of the online fans feel that the fashion used by artists and dancers is more revealing to arouse emotions and attachment to particular songs and artists. Music has long been known to influence fashion trends throughout the world. From music genres that emerged in different decades, musicians who have changed the way people dress and songs that capture a specific style or mood, music and fashion is undeniably intertwined.
Unique Contribution to Theory, Practices and Policies: The Roland Barthes theory and Music theory may be used to anchor future studies in the fashion sector. The study results will also benefit other stakeholders such as the policy makers as well as researchers and scholars from different parts of the world. The top management of fashion industries in the country will also use the study findings to improve music performance in all their activities and programs. The study recommends that the adoption of effective fashion development policies in the fashion industry will help to improve efficiency in their major operations and activities.