bluuebunny/crossref_metadata_2025_split huggingface dataset:
Still central: Change and continuity in Australia's major industrial tribunal
Authors: Bray Mark , Macneil Johanna 
Published: August 2023

AbstractAustralia's major public dispute resolution agency has changed substantially since the 1990s from a stand‐alone tribunal administering a collectivist system of compulsory conciliation and arbitration to an integrated agency resolving both individual and collective disputes as well as performing a broader regulatory role. It remains central to Australian industrial relations, reflecting its adaptability and the peculiarities of its political and industrial relations contexts.
RETRACTED: Assessing the role of combination of stem cell and light‐based treatments on skin wound repair: A meta‐analysis
Authors: Zheng Mingjing , Zhang Huihe , Wu Huizhen , Xie Jiayi , Chen Qiong , Jiang Yue , Zhao Dongrui 
Published: August 2023

AbstractThe meta‐analysis aims to evaluate and compare the impact of the combination of stem cells (SCs) and light‐based treatments (LBTs) on skin wound (SW) repair. Examinations comparing SCs to LBT with SCs for SW repair was among the meta‐analysis from various languages that met the inclusion criteria. Using continuous random‐effect models, the results of these investigations were examined, and the mean difference (MD) with 95% confidence intervals was computed (CIs). Seven examinations from 2012 to 2022 were recruited for the current analysis including 106 animals with SWs. Photobiomodulation therapy (PBT) plus SCs had a significantly higher wound closure rate (WCR) (MD, 9.08; 95% CI, 5.55–12.61, p < 0.001) compared to SCs in animals with SWs. However, no significant difference was found between PBT plus SCs and SCs on wound tensile strength (WTS) (MD, 2.01; 95% CI, −0.42 to 4.44, p = 0.10) in animals with SWs. The examined data revealed that PBT plus SCs had a significantly higher WCR, however, no significant difference was found in WTS compared to SCs in animals with SWs. Nevertheless, caution should be exercised while interacting with its values since all the chosen examinations were found with a low sample size and a low number of examinations were found for the comparisons studied for the meta‐analysis.
Unpacking underdetermination: Theoretical challenges in understanding macroecological and biogeographic patterns
Authors: Diniz‐Filho José Alexandre F. , Coelho Marco Tulio Pacheco , Terribile Levi Carina 
Published: August 2023

AbstractMacroecology and biogeography have made significant strides in understanding the patterns and processes underlying biodiversity, yet the problem of underdetermination (the Duhem–Quine thesis) remains an ongoing challenge. Underdetermination arises when multiple explanations are consistent with the observed data, resulting in challenges in theory and model development and testing. Here, we explore the different forms of underdetermination in macroecology and biogeography and their implications for understanding biodiversity patterns. We highlight the gradient ranging from optimistic to pessimistic views in addressing the problem, coupled then with realistic and instrumentalist scientific reasonings, illustrating these issues by evaluating how underdetermination may affect our understanding of the latitudinal diversity gradient. We show how evolution and diversification introduce a new and unexpected source of underdetermination, and that unpacking the underdetermination problem in macroecology and biogeography requires deconstruction methods in a more comprehensive and integrated approach that considers both hierarchical scale and phylogenetic relationships between organisms and trait‐based explanations.
Association of salivary TREM‐1 and PGLYRP1 inflammatory markers with non‐communicable diseases
Authors: Silbereisen Angelika , Lira‐Junior Ronaldo , Åkerman Sigvard , Klinge Björn , Boström Elisabeth A. , Bostanci Nagihan 
Published: August 2023

AbstractAimTriggering receptor expressed on myeloid cells 1 (TREM‐1) and peptidoglycan recognition protein 1 (PGLYRP1) are elevated in biofluids in the presence of various inflammatory conditions. This cross‐sectional study aimed to evaluate the effect of age, sex, smoking and different oral and systemic non‐communicable diseases on the levels of TREM‐1 and PGLYRP1 in saliva.Materials and MethodsIn total, 445 individuals (mean age 48.7 ± 16.9 years, female:male 51%:49%) were included. All provided self‐reported information on smoking and systemic diseases and whole stimulated saliva. Periodontal and cariological parameters were recorded. Salivary levels of TREM‐1, PGLYRP1 and total protein were measured using commercially available assays.ResultsSalivary TREM‐1 levels were significantly higher in stages III–IV periodontitis compared to other periodontal diagnoses (p < .05). Smoking, bleeding on probing (BOP), percentage of pockets ≥4 mm and the number of manifest caries were associated with TREM‐1 (p < .05), while sex, BOP, number of manifest caries and muscle and joint diseases were associated with PGLYRP1 (p < .05).ConclusionsSalivary TREM‐1 is associated with periodontitis and caries, while PGLYRP1 is associated with gingival inflammation and caries. Additionally, TREM‐1 levels are modified by smoking, while PGLYRP1 is modified by sex and muscle and joint diseases. TREM‐1 and PGLYRP1 in saliva could serve as potential biomarkers for detecting and monitoring non‐communicable diseases.
Atonal homolog 7 (ATOH7) confers neuroprotection for photoreceptor cells in glaucoma via inhibition of the notch pathway
Authors: Yin Yuan , Wu Shuai , Niu Lingzhi , Huang Shiwei 
Published: August 2023

AbstractSingle‐cell RNA sequencing (scRNA‐seq) technologies enable the profiling and analysis of the transcriptomes of single cells and hold promise for clarifying gene mechanisms at single‐cell resolution. We based this study on scRNA‐seq data to reveal glaucoma‐related genes and downstream pathways with neuroprotection effects. The scRNA‐seq datasets related to glaucoma of retinal tissue samples of human beings and Atonal Homolog 7 (ATOH7)‐null mice were obtained from the GEO database. The 74 top marker genes and 20 cell clusters were obtained in human retinal tissue samples. The key gene ATOH7 was found after the intersection with genes from GeneCards data. In the ATOH7‐null mouse retinal tissue samples, pseudotime inference demonstrated significant changes in cell differentiation. Moreover, mouse retinal photoreceptor cells (PRCs) were cultured and treated with lentivirus carrying oe‐ATOH7 alone or in combination with Notch signaling pathway activator Jagged‐1/FC, after which cell biological functions were determined. The involvement of ATOH7 in glaucoma was identified through regulating PRCs. Furthermore, ATOH7 conferred neuroprotection in PRCs in glaucoma by mediating the Notch signaling pathway. In vitro data confirmed that ATOH7 overexpression promoted the differentiation of PRCs and inhibited their apoptosis by suppressing the Notch signaling pathway. The evidence provided by our study highlighted the involvement of ATOH7 in the blockade of the Notch signaling pathway, resulting in the neuroprotection for PRCs in glaucoma.image
Pandemic precarity: COVID‐19's impact on Mexican and Central American immigrant families
Authors: García Melissa J. , Brooks Caroline V. , Ambriz Denise , Ekl Emily A. , Smith Nicholas C. , Maupomé Gerardo , Perry Brea L. 
Published: August 2023

AbstractObjectiveThis study examines the association of gender, parenthood, and marriage with reports of perceived pandemic precarity among Mexican and Central American immigrants during the COVID‐19 pandemic (Fall 2020) to understand predictors of vulnerability in periods of crisis.BackgroundLatinos/as, immigrants, parents, and women have faced significant challenges during the COVID‐19 pandemic. Family structure, along with social expectations for gender (i.e., self‐sacrificing femininity for women and hegemonic masculinity for men), parenthood, and marriage may explain perceptions of pandemic precarity—defined as the material deprivation and economic anxiety resulting from the COVID‐19 pandemic.MethodThis study used data from the Hispanic COVID‐19 Rapid Response Study (n = 400), a follow‐up of the VidaSana Study of Mexican and Central American immigrants, to examine how family structure is associated with pandemic precarity (i.e., food, housing, and economic insecurity). Using linear regression models, average marginal effects (AMEs), and tests for group differences, we investigate the independent and interactive effects of gender, parenthood, and marriage on pandemic precarity.ResultsMen and parents reported the highest pandemic precarity. Fathers reported higher pandemic precarity than mothers. For men, marriage is associated with greater precarity, and for women, marriage is associated with less precarity, yet marriage increased precarity for those without children.ConclusionWe discuss the importance and implications of examining gender along with family structure to understand how immigrant families were faring in response to the pandemic.
The parent bodies of CR chondrites and their secondary history
Authors: Prestgard Trygve , Beck Pierre , Bonal Lydie , Eschrig Jolantha , Gattacceca Jérôme , Sonzogni Corinne , Krämer Ruggiu Lisa 
Published: August 2023

AbstractRenazzo‐type (CR) chondrites are a relatively rare group of carbonaceous chondrites with the vast majority having escaped thermal alteration. This means that CRs are composed of relatively unprocessed material, depending on the extent of aqueous alteration they have experienced. Hydration in CRs ranges from incipient alteration of matrix glass, up to nearly complete replacement of the rock by hydration products. The extent of secondary processes is often difficult to assess in these meteorites, due to their heterogeneity and diversity of alteration products. Yet, this is crucial in order to understand the extent of geological processing that occurred on the primary parent body. Additionally, the parent asteroids of CRs remain a mystery, mainly because terrestrial oxyhydroxide signatures dominate the reflectance spectra of CRs. In this work, we have conducted optical and IR reflectance and transmission spectra of 25 CR chondrites in order to (i) better evaluate the extent of aqueous alteration that occurred on the CR parent body, and (ii) find possible parent body candidates. Terrestrial oxyhydroxides were removed from 12 samples, as these tend to interfere with the optical‐IR spectra of CRs. Our results suggest, among other, that (i) aqueous alteration in most of our CRs was limited to the matrix and (ii) most CRs may stem from a continuum of X‐to‐C complex asteroids, depending on their extent of aqueous alteration. More specifically, the endmembers being Xk/Xn types and Cgh/Ch types. This has strong implication in regard to what we can expect from the Psyche mission.
Cinemeducation: A mixed methods study on learning through reflective thinking, perspective taking and emotional narratives
Authors: Rueb Mike , Rehfuess Eva A. , Siebeck Matthias , Pfadenhauer Lisa M. 
Published: August 2023

AbstractIntroductionCinemeducation describes the use of film in medical education. The M23 Cinema (M23C) comprises a film screening and subsequent discussion with experts, affected persons and the audience. Previous research suggests that participating in cinemeducation may affect emotions and attitudes. This study aimed to establish a conceptual framework and explore when learning takes place, how learning occurs and what participants learn during the M23C.MethodsInformed by focused literature searches, discussions of the authors and the research results, a conceptual framework of the M23C was developed, comprising three dimensions (five distinct phases, learning methodology and potential impact). A mixed method study was undertaken, employing an exploratory sequential design. Initially, the qualitative component was conducted by interviewing everyone involved, comprising focus groups, expert interviews, a group interview and one narrative interview. All qualitative data were analysed using qualitative content analysis. The qualitative findings were used to inform the development of a survey among the participants of M23C evenings. The survey results were analysed descriptively. The findings generated by both data sets were integrated using the “following a thread” protocol and visualised by joint displays.ResultsIn total, 15 participants in M23C courses, six members of the current and two of the former organising committee, two experts, two affected persons and the initiator of the M23C were included in the qualitative component (n = 28). A total of 503 participants responded to the survey. The qualitative data confirmed the relevance of the five phases and participants described reflective thinking, perspective taking and emotional narratives as the three dimensions of how they learned during the M23C. Participants reported a change in attitudes, enriching their knowledge, experiencing empathy and learning about other health professions.DiscussionOur findings suggest that the M23C as a cinemeducation course provides a unique learning environment in the training of health professionals.
Strange bedfellows: Why right‐wing intellectuals in South Korea chose to cooperate with their country's former coloniser
Authors: Yang Myungji , Asahina Yuki 
Published: August 2023

AbstractWhy and when do today's Far‐Right groups cooperate across national boundaries? This paper seeks to provide answers to these questions by examining a deviant rather than representative case: the transnational connections between right‐wing intellectuals in South Korea and Japan. Analysing the recent publication of a highly controversial and provocative book and the transnational politics around it, we emphasise the roles of right‐wing intellectuals and the processes by which divergent political interests converge in changing geopolitical and domestic political contexts. By situating Far Right activities in its broader context of shaping—colonial history, American hegemony and the confrontation with socialist regimes such as China and North Korea—this paper develops a contextual account of the transnational Far Right.
The power of patterns: new insights into pattern‐triggered immunity
Authors: Shu Lin‐Jie , Kahlon Parvinderdeep S. , Ranf Stefanie 
Published: August 2023

SummaryThe plant immune system features numerous immune receptors localized on the cell surface to monitor the apoplastic space for danger signals from a broad range of plant colonizers. Recent discoveries shed light on the enormous complexity of molecular signals sensed by these receptors, how they are generated and removed to maintain cellular homeostasis and immunocompetence, and how they are shaped by host‐imposed evolutionary constraints. Fine‐tuning receptor sensing mechanisms at the molecular, cellular and physiological level is critical for maintaining a robust but adaptive host barrier to commensal, pathogenic, and symbiotic colonizers alike. These receptors are at the core of any plant‐colonizer interaction and hold great potential for engineering disease resistance and harnessing beneficial microbiota to keep crops healthy.
Taking the lead: NLR immune receptor N‐terminal domains execute plant immune responses
Authors: Chia Khong‐Sam , Carella Philip 
Published: August 2023

SummaryNucleotide‐binding domain and leucine‐rich repeat (NLR) proteins are important intracellular immune receptors that activate robust plant immune responses upon detecting pathogens. Canonical NLRs consist of a conserved tripartite architecture that includes a central regulatory nucleotide‐binding domain, C‐terminal leucine‐rich repeats, and variable N‐terminal domains that directly participate in immune execution. In flowering plants, the vast majority of NLR N‐terminal domains belong to the coiled‐coil, Resistance to Powdery Mildew 8, or Toll/interleukin‐1 receptor subfamilies, with recent structural and biochemical studies providing detailed mechanistic insights into their functions. In this insight review, we focus on the immune‐related biochemistries of known plant NLR N‐terminal domains and discuss the evolutionary diversity of atypical NLR domains in nonflowering plants. We further contrast these observations against the known diversity of NLR‐related receptors from microbes to metazoans across the tree of life.
A Comparison of Outcomes between the Wiltse Approach with Pedicle Screw Fixation and the Percutaneous Pedicle Screw Fixation for Multi‐Segmental Thoracolumbar Fractures
Authors: Zhang Yadong , Wang Wentao , Bai Lulu , Hao Dingjun 
Published: August 2023

ObjectiveMulti‐segmental thoracolumbar fracture (MSF) generally refers to fractures occurring in two or more segments of the thoracolumbar spine. With the development of minimally invasive concept, there is little research on its application in the field of MSF. The purpose of this study is to compare two minimally invasive surgical techniques and determine which one is more suitable for treating patients with neurologically intact MSF.MethodsWe retrospectively analyzed the clinical data of 49 MSF patients with intact nerves who were admitted from January 2017 to February 2019. Among them, 25 cases underwent percutaneous pedicle screw fixation (PPSF), and 24 cases underwent Wiltse approach pedicle screw fixation (WAPSF). The operation time, number of fixed segments, blood loss, length of incision, postoperative ambulation time, accuracy of pedicle screw placement, facet joint violation (FJV), number of C‐arm exposures, as well as pre‐ and postoperative visual analogue scale (VAS), Oswestry disability index (ODI), local Cobb's angle (LCA), and percentage of anterior vertebral body height (PAVBH) were recorded for both groups. Paired sample t‐test was used for intra‐group comparison before and after surgery while independent sample t‐test was used for inter‐group comparison.ResultsThe differences in the number of fixed segments, intraoperative bleeding, postoperative bed time, accuracy rate of pedicle screw placement, VAS, and ODI between the two groups were not statistically significant (p > 0.05). However, the operative time and total surgical incision length were significantly shorter in the WAPSF group than in the PPSF group (p < 0.05), and the FJV was significantly higher in the PPSF group than in the WAPSF group (p < 0.05). Also, the PPSF group received more intraoperative fluoroscopy (p < 0.05). The result of LCA and PAVBH in the WAPSF group were significantly better than in the PPSF group (p < 0.05).ConclusionsBoth PPSF and WAPSF were found to be safe and effective in the treatment of MSF without neurological deficits through our study. However, considering radiation exposure, FJV, vertebral height restoration, correction of kyphosis, and learning curve, WAPSF may be a better choice for neurologically intact MSF.
Metallosis‐Induced Conversion Shoulder Arthroplasty: A Unique Experience and Literature Review
Authors: Ji Jong‐Hun , Park Sang‐Eun , Parikh Darshil , Lee Woojin , Jeong Jinyoung , Park Hyun Woo , Oh Seungbae 
Published: August 2023

BackgroundTotal shoulder arthroplasty (TSA) can fail for several reasons, such as component loosening, periprosthetic fracture, instability, infection, soft tissue failure, or joint overstuffing. Severe metallosis without loose glenoid components after TSA may result in the need for revision to reverse TSA.Case presentationFour years before the current presentation, an 86‐year‐old woman suffered from right shoulder pain and swelling. The initial diagnosis was osteoarthritis of the shoulder joint, for which she underwent TSA. Four years later, she complained of shoulder joint pain, swelling, and limited range of motion. On sonography, subscapularis and supraspinatus tendon tears were identified. Plain radiographs and computed tomography (CT) scans showed metallosis around the shoulder joint. Due to the rocking horse mechanism, wear of the upper portion of the glenoid component and bearing caused a foreign‐body reaction and severe metallosis around the joint. Due to a massive rotator cuff tear combined with glenoid component wear, the patient eventually underwent reverse TSA (RTSA) and was satisfied with the final results.ConclusionsSevere metallosis due to glenoid component wear combined with a massive rotator cuff tear in TSA may cause the need for revision to RTSA.
Diagnosing psychiatric disorders from history of present illness using a large‐scale linguistic model
Authors: Otsuka Norio , Kawanishi Yuu , Doi Fumimaro , Takeda Tsutomu , Okumura Kazuki , Yamauchi Takahira , Yada Shuntaro , Wakamiya Shoko , Aramaki Eiji , Makinodan Manabu 
Published: August 2023

AimRecent advances in natural language processing models are expected to provide diagnostic assistance in psychiatry from the history of present illness (HPI). However, existing studies have been limited, with the target diseases including only major diseases, small sample sizes, or no comparison with diagnoses made by psychiatrists to ensure accuracy. Therefore, we formulated an accurate diagnostic model that covers all psychiatric disorders.MethodsHPIs and diagnoses were extracted from discharge summaries of 2,642 cases at the Nara Medical University Hospital, Japan, from 21 May 2007, to 31 May 31 2021. The diagnoses were classified into 11 classes according to the code from ICD‐10 Chapter V. Using UTH‐BERT pre‐trained on the electronic medical records of the University of Tokyo Hospital, Japan, we predicted the main diagnoses at discharge based on HPIs and compared the concordance rate with the results of psychiatrists. The psychiatrists were divided into two groups: semi‐Designated with 3–4 years of experience and Residents with only 2 months of experience.ResultsThe model's match rate was 74.3%, compared to 71.5% for the semi‐Designated psychiatrists and 69.4% for the Residents. If the cases were limited to those correctly answered by the semi‐Designated group, the model and the Residents performed at 84.9% and 83.3%, respectively.ConclusionWe demonstrated that the model matched the diagnosis predicted from the HPI with a high probability to the principal diagnosis at discharge. Hence, the model can provide diagnostic suggestions in actual clinical practice.
Efficacy of medical treatments for pediatric hidradenitis suppurativa: A systematic review
Authors: Masson Rahul , Ma Elaine , Parvathala Neha , Shih Terri , Atluri Swetha , Hogeling Marcia , Hughes Meagan , Sayed Christopher J. , Shi Vivian Y. , Hsiao Jennifer L. 
Published: August 2023

AbstractHidradenitis suppurativa (HS) is a chronic, inflammatory skin condition that has been insufficiently studied in the pediatric population. Timely and effective medical treatments may improve quality of life, mitigate disease burden, and prevent the need for invasive procedural interventions such as surgical excisions. However, there is a paucity of research on the efficacy of medical management strategies for HS in children and adolescents. The aim of this study was to perform a systematic review of the literature on the efficacy and safety of medical treatments for HS in patients <18 years of age. In April 2022, MEDLINE and EMBASE databases were searched for articles on the efficacy of medical treatments for HS in the pediatric population. Between 1984 and 2022, 35 articles (101 patients) met the inclusion criteria. Most patients had Hurley Stage II disease (46.7%, 35/75) followed by Stage I (36%, 27/75), and Stage III (17.3%, 13/75). 100% (23/23) of patients responded to antibiotics, 100% (8/8) to finasteride, 93.9% (31/33) to biologics, 80% (4/5) to oral retinoids, and 50% (6/12) to metformin. Overall, this study demonstrates that medical treatment regimens can improve HS symptoms in pediatric patients, but the extent of improvement is unclear, and the results were largely based on case reports or case series. Prospective studies are warranted to better understand the efficacy and safety of medical treatments for pediatric HS. Clinical trials of HS therapies need to be inclusive of pediatric patients to help define the optimal timing of treatment initiation and guide patient selection.