bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between Tumor-Infiltrating Lymphocytes and Histopathological Types of Thyroid Carcinoma in Department of Anatomical Pathology, University of Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital
Authors: Kamarudy Lay Fanny , Stephanie Harahap Agnes , Francisca Ham Maria 
Published: September 2023

Background
The presence of tumor-infiltrating lymphocytes (TILs) has been widely explored as one of the factors that can affect the success of immunotherapy in various cancers. This study aims to investigate the TILs in various types of thyroid carcinoma (TC) and its association with the aggressive histopathological type compared to the less aggressive histopathological type of TC.
Methods
The population covered by this retrospective study was TCs diagnosed at the Department of Anatomic Pathology, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, period 2015-2019. The research sample was divided into group of TCs with aggressive histopathological type and less aggressive histopathological type with a total of 25 samples for each group. TILs was calculated in 10 high power fields (HPF) with 400 kali magnification. The analyses were conducted using Mann-Whitney and Kruskal Wallis test.
Results
TILs count was found with a median value of 43 (3-660) in the aggressive histopathological group and 36 (9-387) in the less aggressive histopathological group (p:0.96, CI:95%). The highest TILs was found in anaplastic thyroid carcinoma (ATC) and papillary thyroid carcinoma (PTC) with anaplastic components. TILs count was also found with a median value of 17.5 (3-75) in male and 48 (9-660) in female (p:0.02, CI:95%).
Conclusion
There was no significant association between TILs and histopathological types of TC (aggressive and less aggressive). However, there is a tendency for high TILs in ATC and PTC with anaplastic components. There is also a significant difference in TILs between male and female gender.
Correlation between Microvessel Density Based on CD31 Immunohistochemical Expression and Clinicopathology of Invasive Breast Carcinoma
Authors: Bitaria Febrawati Eka , Alferraly T. Ibnu , Betty Betty 
Published: September 2023

Background
Breast carcinoma is the most common malignancy in women worldwide. Tumor size, metastases, lymph node involvement (KGB), stage and histopathological grade are significant prognostic factors in invasive breast carcinoma. Microvessel density (MVD) assessment is used to measure angiogenesis which helps predict tumor behavior and the effect of antiangiogenic therapy. MVD is a quantitative calculation of intratumoral capillary blood vessels which reflects the results of the process of angiogenesis. The aim of this study was to analyze the relationship between MVD based on CD31 immunohistochemical expression and the clinicopathology of invasive breast carcinoma.

Method
Cross sectional analytic study with 42 samples diagnosed with invasive breast carcinoma at H. Adam Malik General Hospital Medan. MVD is the number of small blood vessels in terms of size and diameter (arterioles and venules) with a round lumen that is positively stained with CD31 at 10 large visual fields, categorized as low if <45 blood vessels/10 LPB and high if ≥45 blood vessels/10 LPB. The relationship between MVD and several clinicopathological parameters was analyzed using the Chi-Square, Fisher's Exact and Mann-Whitney tests.

Results
There was a significant relationship between tumor size (p=0.029), metastasis (p=0.014), stage (p=0.002), histopathological grade (p=0.0043), LVI (p=0.002), TILs (p=0.007). Large tumor size, metastases, high histopathological stage and grade, positive LVI and high TILs were significantly associated with MVD. However, there was no significant relationship between KGB involvement (p=0.570) and MVD.

Conclusion
MVD is significantly related to tumor size, metastases, stage, histopathological grade, LVI and TILs, and not significantly related to lymph node involvement. MVD plays a role in the angiogenesis of invasive breast carcinoma clinicopathology.
The Association of Fibulin-2 Expression with Histopathological Grade and Fibrotic Tumor Vessel in Meningioma
Authors: Kamelia Muthia , Agus Salmiah , Tofrizal Tofrizal 
Published: September 2023

Background
Meningiomas are the most common primary tumors of the central nervous system. About one-fifth of meningiomas tend to recur. The World Health Organization (WHO) histopathological grade was the most useful morphological predictor of recurrence. Fibrotic tumor vessels (FTV) were detected in nearly half of WHO grade I meningiomas and correlated with vascular density and increased risk of recurrence. Fibulin-2 is an extracellular matrix glycoprotein whose expression increases in traumatic central nervous system injuries and can be used as a marker to differentiate the histopathological grade of meningiomas. This study aimed to determine the association of fibulin-2 expression with histopathological grade and FTV in meningiomas.

Methods
This research was an observational cross-sectional study. The study sample was 36 cases of meningioma in three Anatomical Pathology laboratories in West Sumatra on period January 2019 to December 2020. Samples obtained from resected meningioma cases were then reevaluated on Hematoxylin Eosin (HE) slides to determine the histopathological grade and FTV. Van-Gieson staining was performed to confirm FTV. Fibulin-2 expression in tumor cells was analyzed using immunohistochemical staining. Bivariate statistical analysis using the Chi-Square test with p<0.05 was considered significant.

Result
High-risk meningiomas (WHO grade II and III) showed high fibulin-2 expression (62.5%), whereas low-risk meningiomas (WHO grade I) were more abundant with low fibulin-2 expression (75%). The presence of FTV at low fibulin-2 expression was 58.3%. Statistical analysis showed no significant association between fibulin-2 expression with histopathological grade (p=0.077) and FTV (p=1,000).

Conclusion
In summary, the study showed that fibulin-2 expression was not associated to histopathological grade nor to FTV in meningiomas.
Dalit Feminism and the Intersection of Class, Caste and Gender in The Prisons We Broke by Baby Kamble
Authors: Runa  , Sahar Rahman  
Published: September 2023

Dalit feminism emerged as a response to mainstream Indian feminism, which tended to downplay caste related issues. Dalit feminism studies not only the patriarchal oppression of Dalit women at the hands of upper-caste men but also from the members within their own caste. Baby Kamble grapples with this issue as a writer as well as an activist. This paper attempts to study the intersectional impact of caste, gender and class in her work The Prisons We Broke using the Dalit feminist theoretical approach. It attempts to analyse the textual representation of Dalit women’s predicament not only through the portrayal of the interlinked complexity of caste, gender and class-based oppressions but also through the intersection and overlapping of these realities within the autobiographical rubric of writing. In her seminal work, Baby Kamble exposes the deprivation of Dalits and the struggles and oppression of Dalit women. Kamble seems to immerse or place herself within the community but does not leave out the complexity of identity for a Dalit woman. Her autobiography thus disrupts the standard concepts of autobiography that place individual at the centre. As opposed to the existing gap among mainstream feminist movement, there seems to be a scope to reshape feminist solidarity among the Dalit feminist scholarship. This paper builds upon the major concerns shared by Dalit feminists within the social structures that assert the subjugation of Dalit women using the lens of caste and gender. It further attempts to extend the theoretical scope and applicability of Dalit feminism by exploring the conceptual specificity of the social reproduction of the social location-based knowledge of Dalit women’s predicament.
Interprétation de la Musique mixte - transfert de technologie, authenticité et fidélité : étude de cas du développement de la version temps réel d’Inharmonique (1977) de Jean-Claude Risset
Authors: Ferreira José Luis 
Published: September 2023

Cet article est la traduction révisée d’une partie de la thèse de José Luis Ferreira, qui présente le projet « Jean-Claude Risset’s Inharmonique : recast and a real time version proposal » en partenariat avec António de Sousa Dias. Les objectifs du projet étaient le transfert de technologie intégral avec sa documentation et la proposition d’une version en temps réel de cette œuvre. Il s’agit du rapport de la première ébauche du projet. Dans un premier temps, l’auteur introduit le concept de système de relations dynamiques et l’applique par la suite au portage de la pièce de Risset.
Analyse créative en recherche-création : trois exemples d’appropriation à partir du recodage d’Inharmonique de Jean-Claude Risset
Authors: Dia António de Sousa , Bonardi Alain , Svidzinski Joao 
Published: September 2023

L’objectif de cet article est de montrer comment les auteurs se sont approprié le travail d’analyse-recodage d’Inharmonique de Jean-Claude Risset dans leurs propres créations. Cette version augmentée et révisée d’un précédent article publié dans les Actes des Journées d’informatique musicale 2020 présente tout d’abord la modélisation orientée objet-opératoire. Sont ensuite examinées des pièces issues du processus d’analyse-recodage : Les cris du sixième cercle (2019) de João Svidzinski, hérite de la notion d’objet et la prolonge. Dans la nef de nos songes 1 (2019) d’Alain Bonardi et TêTrês (2001) d’António de Sousa Dias, ont recours de manière explicite aux codes de Risset. Ces trois cas d’héritage se révèlent essentiels pour le recodage d’Inharmonique. Cette approche d’analyse-création est au cœur de notre activité de compositeurs et de chercheurs.
Présentation d’Inharmonique : interview avec Irène Jarsky
Authors: Jarsky Irène , Tiffon Vincent 
Published: September 2023

Cette interview avec Irène Jarsky, la soprano qui a créé et participé à la genèse d’Inharmonique, nous fait découvrir une facette de l’œuvre parfois inconnue du public. Parmi les points les plus remarquables, signalons : le processus de composition dans les années 1970, l’interaction entre le compositeur et l’interprète, et surtout, les nuances interprétatives qui dépassent la notation musicale traditionnelle. Plus de quarante ans après la création de l’œuvre, cette interview montre que plusieurs questions restent encore d’actualité, notamment celle ayant trait à la recherche-création. Cela atteste de son caractère novateur et de sa place d’honneur dans le répertoire musical contemporain de la fin du XXe siècle.
Molecular Identification of Malaria Vector in Gusau Township, Nigeria
Authors: Abdullahi K. , Moyi S. I. , Abdulazeez M.T. 
Published: September 2023

There about 460 Anopheles species recognized, over 100 can transmit human malaria but only 30–40 commonly transmit parasites of the genus Plasmodium, which cause malaria. Anopheles gambiae is the principal vector of the most dangerous malaria parasite species in Africa, which is Plasmodium falciparum. Anopheles gambiae are a complex consisting of eight morphologically indistinguishable species and each of the members of the complex having unique biology, ecology and behaviour and should be studied and differentiated. The research objective was to identify the species of malaria vector in Gusau township Nigeria using molecular biological technique to know the exact malaria vector. Knowledge of the exact malaria vector in a given environment enables formulating a carefully designed tailor-made vector control measure. Indoor and outdoor mosquito samples were collected from selected areas in five wards of Gusau township using standard collection methods, for a period of twelve months. The samples were identified using polymerase chain reaction (PCR) technique and the result showed Anopheles gambiae in all sites of sample collection. It is therefore recommended that integrated malaria vector control should be adopted in the mosquito control programme because Anopheles gambiae is rugged and can be difficult to control and/or eradicate because of the emerging insecticide resistance and its close association with human host.
Interessenvertretungen in der Digitalisierung. Zur Bedeutung betriebspolitischer Aktivierungsprojekte der Gewerkschaften am Beispiel von „Arbeit 2020 in NRW“
Authors: HAIPETER THOMAS , SCHILLING GABI 
Published: September 2023

Der Beitrag geht der Frage nach, welche Handlungsmuster Betriebsräte im Umgang mit Digitalisierungsprozessen entwickeln und welche Rolle dabei gewerkschaftliche Aktivierungsprojekte spielen können, die darauf abzielen, die Handlungsfähigkeit der Betriebsräte zu verbessern. Dazu wird das Beispiel des gewerkschaftlichen Projekts „Arbeit 2020 in NRW“ herangezogen, das als eines der zentralen Projekte einer gewerkschaftlichen Betriebspolitik zur Digitalisierung betrachtet werden kann. Der Projektfokus auf die Aktivierung zu gestaltungsorientierter und strategisch ausgerichteter Betriebsratsarbeit steht in deutlichem Kontrast zu anderen Forschungsbefunden, denen zufolge Interessenvertretungspolitik der Betriebsräte zumeist reaktiv und auf – die zweifellos wichtigen – Schutzinteressen ausgelegt ist. Die Autorin/der Autor beleuchten in diesem Beitrag, welche Möglichkeiten und Grenzen einer Verbesserung der Handlungsfähigkeit der Betriebsräte durch gewerkschaftliche Aktivierungsprojekte bestehen und was daraus für die Verbreitung neuer Interessenvertretungspraktiken und für das Zusammenspiel von Gewerkschaften und Betriebsräten folgt.
El Pretensado en las estructuras de acero
Authors:   , Costales Calvo Ignacio 
Published: September 2023

En 1879 nace Eugène Freyssinet, padre reconocido del hormigón pretensado. Cuarenta años antes de su nacimiento,
ingenieros americanos ya habían empezado a pretensar perfiles de hierro fundido, para evitar que cuando éstos entrasen
en tracción, se quebraran. Ciento setenta años después el hormigón armado pretensado se estudia en centenares de
artículos, revistas especializadas y tesis doctorales diversas, mientras que el acero pretensado no ha tenido el mismo
desarrollo desde unos cincuenta años atrás. Raras son las ocasiones dónde se llega a justificar que pretensar una
estructura metálica es necesario y razonable económicamente. Si nos centramos en estructuras de edificación, aún serán
menos estas ocasiones. La presente tesis estudia la historia de las estructuras metálicas pretensadas, la mayoría de
edificación, algunas de ellas a fondo, como las recientemente construidas en Catalunya. También se repasan las
posibilidades que el pretensado metálico ofrece al consultor de estructuras, completándolo con algunos ejemplos. Se
ofrece un análisis pormenorizado de la viga Fink, con especial cuidado en su predimensionado y en el cálculo tanto manual,
como matricial. Se incluye un análisis de refuerzo de techos formados por viguetas reforzadas trasnversalmente por una
viga que cambia su rigidez según criterio del proyectista. Al final se desarrolla una solución de unión de viga y pilar metálico
unidos mediante tendones pretensados, para facilitar el montaje en obra, resolviendo las holguras gracias a la unión
mediante nudos semirrígidos.
Eugène Freyssinet, born in 1879, is the acknowledged father of prestressed concrete. Forty years before his birth, American
Engineers had begun to prestress cast iron profiles to prevent them from breaking after entering in tension. One hundred and
seventy years after prestressed concrete is studied in hundreds of articles, journals and diverse dissertations, while
prestressing of steel has not had the same development since about fifty years ago. Rare are the occasions where the
technician is able to justify that prestressing steel structures is necessary and economically reasonable. If we are
considering building structures, these occasions to presstress the structure will be even less. This thesis studies the history
of prestressed steel structures, some of them in depth, as some of thoses recently built in Catalonia. It also reviews the
possibilities that metallic prestressed structures offer to the consultant, including some examples. It provides a detailed
analysis of the Fink truss beam, with special care in their pre-dimensioning and calculation both manually as matrix. It
includes an analysis of strengthening reinforced slabs, with a beam that changes its stiffness at the discretion of the
designer. Eventually it develops a joint solution of a beam and a steel column, connected by prestressed tendons, to make
assembly easier, meeting the gaps with the connection by means of semi-rigid joints.
Human Influence On Global Climate: Legal Protection For Sustenance Of Life On Earth
Authors: Dr. G. Indira Priyadarsini  
Published: September 2023

Changes in solar irradiance may have affected global climate, the importance of the climate change issue stems from the impact of changes in climate on human and natural systems. The two most well-known consequences of climate change are an increase in global-mean temperature and a rise in sea level. The primary components of sea-level rise are thermal expansion and the melting of small glaciers. However, there are other changes in climate could be as important, or even so, than changes in the mean climate state. These include changes in precipitation and climate variability, particularly changes in the intensity and/or severity of extreme events such as droughts, floods, or tropical storms.
Physics deals with the structure of matter and how the fundamental constituents of the universe interact. The impact of humans on the environment revolves around the need of physical science to understand how human beings change a natural system, an understanding of global warming and the associated climate change. Hence, physicists will approach numerous troubles from more than one direction. Physicists had to constantly keep attentive to changes, to visualize one factor going on in nature, to discover new phenomena and to document it in order that they will describe it later. Thus studying physics strengthens quantitative reasoning and problem solving skills. The environment is the natural world but with toxic chemicals, spacecraft, and nuclear bombs, humans seem to be moving further and further away from what could be called 'natural' every day. As physics strengthens quantitative reasoning and problem-solving skills, it should be dealt transdisciplinary with Law will surely helps in reducing human influence on global climate and render legal protection for sustenance of life on earth. Hence the paper concentrates on the importance of application of physical principles to environmental problems and the proactive role played by judiciary in different countries in protecting life on earth by adopting policies relating to climate change, enhancing ethical principles by setting regulations and standards for operating industries.
Identity and conflict
Authors: Fodor Richárd 
Published: September 2023

The study sheds light on several important aspects in the field of textbook research and history didactics. The introduction presents the most significant professional events of the European history didactic discourse in recent years and new approaches to the scientific field, in all of which international cooperation plays an important role. Reasons for the general and professional interest in history teaching and history textbooks and the origin of textbook research are also presented. The history of international textbook revisions, interrupted by the world wars of the 20th century, the types, effectiveness, goals, and results of transnational cooperation are also introduced. Finally, the study details the changing results and products of some cross-border projects, paying special attention to the exemplary French-German textbook revision, the Polish-German, Scandinavian, Slovakian-Hungarian, European perspectives, and Asian and African examples that rarely appear in Hungarian textbook research. In the conclusion of the study more than a dozen collaborations are summarized based on continent, duration, nature of participants, and function. Among the results two categories are established as the main goals: regional identity building and conflict resolution.
القدس محور الصراع سيناريوهات التهويد والتصعيد
Authors: حطيط رولا جميل 
Published: September 2023

Zionism stems from the phrase "God's chosen people", where the Jews are considered a preferred people over all peoples, and that they have a historical right to Palestine, the "promised land", hence the slogan of the Zionist entity "the right to settle everywhere", and imposed its expansionist policy by force Since the establishment of its state in 1948, there has been prolonged settlement of other Arab lands after the "1967 war". The Zionist settlement policy in the occupied Palestinian territories is an expression of the Zionist hegemony strategy in which the entity gives itself the freedom to expand the settlements to other countries.
This is in addition to the international support it enjoys, especially the “American” support, which constitutes the main objection to getting rid of it, which makes the Palestinian issue one of the most complex colonial issues known to history, as it is difficult to solve it in a similar way. to old colonial issues. It remains the focus of attention of the entire international community because of the impact of the Israeli-Palestinian conflict on peace in the region and its repercussions on international peace.
Hence the importance of the issue, especially since the Palestinian issue is in constant development as a result of the expansionist settlement policy practiced by the occupying state, as the existing Israeli-Palestinian conflict, especially the city of Jerusalem, has escalated and its importance.
The current situation, with its dangerous dimensions, is one of the reasons for the necessity of discussing the issue with the aim of reaching an approach to the current situation and finding a solution commensurate with the nature of the issue by raising the different circumstances. Although it is a fair issue.
From this point of view, we chose the topic in the hope that this modest effort will shed more light on the truth that is fundamentally rooted in the inalienable legal rights of the Palestinian people, despite what was violated and what happened in the case in general.
To study the subject, we adopted the analytical descriptive approach and the historical approach, in observing the historical context of the city of Jerusalem, in conjunction with analyzing the accelerating events on a daily basis in this city.
The subject of the research was addressed by highlighting the following titles: the symbolism of Jerusalem and the forms of Judaization therein, the course of Trump's decision to make Jerusalem the capital of "Israel".
Resistance in Jerusalem and a conclusion.
الحرب السيبرانيّة والأداء الإستراتيجيّ الفعال؛ دراسة حالة في الهجَمات السيبرانيّة بين إيران و"إسرائيل"
Authors: أبو عليان د. عبد العزيز محمود 
Published: September 2023

Cyber-attacks have escalated in major countries such as the United States of America, Russia, and China, in light of the advanced information revolution in our contemporary reality, and cyber wars have become clear in different environments, affecting the national security system of countries. Lightly, every country seeks to prove its capabilities to show itself in the electronic arena, as Iran wants to show itself that it has the ability to compete with the United States of America by sending its messages by through launching cyber-attacks to assure its opponents that it is present in the field and that Iran cannot be bypassed in this field, and in In the same framework, Israel delivers unannounced messages in carrying out its cyber-attacks to achieve deterrence and decisiveness in its ability to repel any attack on its institutions, and that it has the ability to strike its enemies at the time it wants and inflict losses on electronic systems.