bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current challenges for the use of phytotherapy: a narrative
Authors: Barbosa Fernando Campos , Tadine Rodrigo Martins , Rezende Janaina Drawanz Pereira , Lopes Gabriel César Dias , Abrao Neto Elias 
Published: May 2023

Considering the phytotherapy increasing use, there are challenges that must be overcome to applying this therapeutic area in a comprehensive way. In order to explore the main obstacles that limit the application of phytotherapy in the health spheres, the aim of this bibliographic review is to offer a summary of the main issues on this topic. In this narrative literature review, studies about the main challenges for the use and development of phytotherapy were selected. Searches were performed in MEDLINE, PUBMED, SCIENCE DIRECT, SciELO and LILACS. In the selected studies, can be cited how main challenges the raw material and bioactive compounds obtaining, regulatory, safety and efficacy evaluation, issues related to quality control and the health professionals training and knowledge. The global acceptance about the herbal medicines and products based on medicinal plants use shows exponential growth. In order to protect users, some issues must be overcome, how regulatory standardization, health professionals adequacy training and quality assurance, efficacy and safety of the products used in phytotherapy.
Estrategias didácticas para el desarrollo de la autonomía en niños del nivel preescolar
Authors: Macías-Zambrano Cinthia Patricia , Henríquez-Coronel María Angélica 
Published: May 2023

El artículo presenta los resultados de una investigación cuyo objetivo fue implementar una estrategia didáctica que favorezca el desarrollo de la autonomía de los niños, la cual fue diseñada en base a los referentes teóricos y en el diagnóstico realizado a través de la autoevaluación, la observación y el focus group aplicados a un grupo de ocho niños.
El trabajo se desarrolló bajo el enfoque cualitativo, tipo de investigación descriptiva, no experimental de corte transversal se obtuvieron resultados que evidenciaron el nivel de desarrollo individual de la autonomía, y sus aportes en la formación de los infantes demostrando su capacidad de decidir para continuar creciendo de manera integral, se concluyó que la intervención de los docentes es central en el desarrollo de la autonomía debido a la relevancia de la aplicación de estrategias didácticas en el ambiente escolar, puesto que favorecen las habilidades del infante, promoviendo independencia creando seres íntegros, autónomos y autosuficientes.
Pengaruh Variasi Diameter O-ring pada Permukaan Silinder terhadap Koefisien Drag
Authors: Tista Si Putu Gede Gunawan , Ghurri Ainul , Putra I Ketut Suanjaya Adi 
Published: May 2023

Dalam aplikasi engineering banyak ditemukan peralatan yang menggunakan silinder, seperti tiang penyangga jembatan, cerobong asap, dan sebagainya. Peralatan-peralatan ini mengalami hembusan udara setiap saat, yang menyebabkan kekuatan konstruksinya mengalami penurunan, hal ini disebabkan adanya drag yang arahnya searah dengan arah aliran. Upaya yang dilakukan untuk mengurangi drag adalah dengan memanipulasi medan aliran fluida. Manipulasi aliran fluida dapat dilakukan secara pasif antara lain dengan menambahkan helical strake pada permukaan silinder, menambahkan penghalang di depan silinder dan sebagainya. Dalam penelitian ini manipulasi aliran fluida dilakukan dengan menambahkan O-ring pada permukaan silinder. Tujuan penelitian ini adalah menganalisa pengaruh variasi diameter O-ring terhadap koefisien drag. Penelitian ini dilakukan pada sebuah wind tunnel yang terdiri dari blower, pipa pitot, manometer, timbangan digital, dan silinder. Penambahan O-ring diletakkan pada permukaan silinder dengan variasi diameter O-ring yaitu 3mm, 4mm, 5mm, 6mm dan jarak antar O-ring 30mm. Silinder diletakkan ke arah vertikal. Bilangan Reynolds berdasarkan diameter silinder (60mm) adalah Re = 3,64 x .Dari hasil penelitian menunjukkan bahwa terjadi penurunan koefisien drag dibandingkan tanpa variasi O-ring. Nilai koesisien drag terendah didapat dari variasi diameter O-ring 5mm atau d/D=0,08 dengan nilai 0,650259, dimana terjadi penurunan drag sebesar 24,15% dibandingkan dengan silinder tanpa O-ring.
The training needs necessary to develop the professional competencies of Sudanese university professors (University of the Noble Qur’an and the Rooting of Science as a model)
Authors:   Assoiate Professor of Fonundation Education University of the Holy Quran and Taseel of science || Gezira State|| Sudan Republic Phone: 00249 126743646|| E: migdad33@gmail.com, Rhamtallah Salih Abd Allah Khalid 
Published: May 2023

Abstract:	This study aimed at knowing the training needs necessary to develop the professional competencies of Sudanese university professors. Professors of the University of the holy Qur’an and Tseel of Science as a model. The training needs helps those in charge of training to design a training program according to a vision stemming from the convictions of the target group. The researcher adopted the descriptive analytical method. The questionnaire was also used as a tool for collecting data. The questionnaire was distributed to a sample of (144) professors, including 111 males and 33 females working in three colleges within the city of Wad Madani (Faculty of education, Sharia and Faculty of education Basic). The results of the study showed that the degree of need of faculty members at the University of the Holy Qur’an and Taseel of Science in the field of planing was great, as each of them obtained an average of (3.71), followed by the evaluation with an average of (3.71).) As for community service, it scored (3.70), followed by scientific research with an average of (3.64), and finally, Taseel (3.62). All of this confirms that training has a role in raising the professional competencies of university professors. There were no statistically significant differences in the study sample regarding the training needs to develop their professional competencies due to the gender variable (male/ female). Based on these results, the researcher presented a number of recommendations and suggestions. الملخص: هدفت هذه الدراسة إلى معرفة الاحتياجات التدريبية اللازمة لتطوير الكفايات المهنية لأساتذة الجامعات السودانية. أساتذة جامعة القرآن الكريم وتأصيل العلوم أنموذجا. مما يساعد القائمين على التدريب من تصميم برنامج تدريبي وفق رؤية نابعة من قناعات الفئة المستهدفة. استخدم الباحث المنهج الوصفي التحليلي. كما استخدمت الاستبانة أداة لجمع المعلومات. وزعت الاستبانة على عينة مكونة من (144) أستاذ منهم 111 ذكور و33 إناث يعملون في ثلاث كليات داخل مدينة ود مدني (التربية، الشريعة والتربية أساس). أظهرت نتائج الدراسة أن درجة حاجة أعضاء هيئة التدريس بجامعة القرآن الكريم وتأصيل العلوم في مجال التخطيط كانت كبيرة حيث حصل كل منهما على متوسط (3.71) ويليهما التقويم بمتوسط (3.71) أما محور الكفايات العامة فقد حصل على متوسط (3.64) أما خدمة المجتمع فقد حصل على (3.70) يليه البحث العلمي بمتوسط (3.64) وأخيرا التأصيل (3.62). كل ذلك يؤكد أن للتدريب دورا في رفع الكفايات المهنية للأساتذة الجامعيين، لا توجد فروق ذات دلالة إحصائية لدي عينة الدراسة تجاه الحاجات التدريبية لتطوير الكفايات المهنية لديهم ترجع لمتغير النوع (ذكر/ أنثي). استنادا لهذه النتائج قدم الباحث عددا من التوصيات والمقترحات.
Implementasi Pendidikan Karakter dalam Pendidikan Agama Islam untuk Meningkatkan Akhlak Peserta Didik Di SMP IT Al-Huda
Authors: Kholik Abdul 
Published: May 2023

Tujuan dari penelitian ini yaitu untuk mengetahui bagaimana implementasi pendidikan karakter dalam PAI untuk meningkatkan akhlak peserta didik di SMP IT Al-Huda Cilamaya Wetan: mulai dari perencanaan, proses pelaksanaan program, penilaian serta identifikasi terhadap faktor yang mendukung dan menghambat pelaksanaan pendidikan karakter. Jenis penelitian ini adalah penelitian lapangan (Field Reseach), dengan menggunakan pendekatan kualitatif. Teknik pengumpulan data yang digunakan yaitu melalui wawancara, observasi, dan dokumentasi, dimana subjek penelitian yang terlibat yaitu kepala sekolah, waka kurikulum, guru bidang studi Pendidikan Agama Islam. Sedangkan teknis analisis data yang digunakan dalam penelitian ini yaitu menggunakan teknik analisis deskriptif. Hasil temuan dalam penelitian ini adalah sebagai berikut : tahap perencanaan, guru menyisipkan nilai-nilai pendidikan karakter ke dalam silabus dan RPP; tahap pelaksanaan, melalui KBM (intrakurikuler) dan ektrakurikuler; tahap penilaian, mengevaluasi input, process, output dan out comes; Faktor pendukung, meliputi guru dan pendidik, lingkungan sosial, dan wali murid yang proaktif memberi dukungan; faktor penghambat, meliputi sarana-prasarana sekolah, orang tua yang sibuk, pengaruh siswa lain.
Development and Optimization of Flakes from Some Selected Locally Available Food Materials
Authors: Tunde Olorunsogo Samuel , Adenike Adejumo Bolanle 
Published: May 2023

Flakes are one of the most popular ready-to-eat breakfast cereals meals. Most traditional instant breakfast meals are from mono-cereals. This work aims to develop, characterize and optimize value-added instant cereal breakfast flakes using flours of rice, sorghum, and soybean. A three-component constrained optimal (custom) mixture experimental design was employed for the formulation. The formulation design constraints were: rice flour (30%–35%), sorghum flour (20%–25%), and soybean flour (5%–10%). Other ingredients were water (19%), sugar (8%), malt (2%), egg (3%), sweet potato (3%), ginger (2%) and moringa seed powder (3%). The formulated samples were analysed and evaluated based on standard procedures for quality characteristics. Numerical optimization gave the optimal product\'s overall desirability index of 0.519 obtained from 31.9 % rice flour, 22% sorghum flour, and 6.05% soybean flour; with quality properties as follows: 3.67% moisture content, 3.18% fat content, 3.08% ash content, 1.44% crude fibre, 30.0% crude protein, 58.6% nitrogen-free extract, 384 kcal energy value, and 7.28 overall acceptability. The result of the study showed that the nutritional qualities of cereal flakes can be improved through food-to-food composite formulations, employing numerical optimization technique.
Design and Implementation of Disease Diagnosis System Using Unified Networks
Authors:   Assistant Professor, Department of Computer Science and Engineering, KSR Institute For Engineering and Technology, Namakkal, Tamil Nadu, India., P Nithya , P Barath , D Prathap , M Santhosh , A Yuvaraj 
Published: May 2023

Children with the autism spectrum disorder have been shown to have difficulty with social and emotional interaction. Most of individuals lack the context they need to produce social reactions through voice and gaze. Since emotion plays a role for successful social connection, it is understandably crucial for children to be able to recognise and express feelings appropriately. A sort of emotional state, emotion can be recognised by internally indications and physiological responses. In general, patches are put onto the skin or body of autistic children in order to assess signals connected to the identification of emotional states from physical reactions as speech and facial expression. The children would probably be unpleasant as an outcome and their "true" emotions would be disguised. The study suggested employing thermal imaging as a passive medium to selectively analyze the physiological signals related to the emotions.	Pursuant to the study's the hypothesis, the various emotional conditions of autistic children could be directly affected by the epidermal variations in temperature carried about by the rapid blood flow in the blood capillaries at the front face area as assessed by the modality. To calculate the thermal imaging data generated by different emotions and expressions caused by different kinds of multimedia stimuli, a structured experimental establishing was created.The changes measured from the region of interest have been determined using a wavelet-based technique for pattern detection over time series. The impact state model for typically developing kids between the ages of 5 and 9 was utilised in the study as the baseline to assess how well the affective state classifiers worked for kids without autism. Key Word: Autism, psychological conditions, the temperature on the skin on the human face, thermal regulation, or thermal imagery
DECISION MAKING (Landasan Teologis, Filosofis, Psikologis dan Sosiologis Kepemimpinan Pendidikan di MA Al-Karimiyah)
Authors: Patih Ahmad 
Published: May 2023

Pengambilan keputusan merupakan kegiatan yang biasa dihadapi oleh seorang pimpinan organisasi pendidikan Islam atau madrasah. Tentu saja, pengelolaan satuan pendidikan di pondok pesantren memerlukan perhatian lebih dari pada di luar pesantren, dan semua kebijakan harus terkait dengan visi dan misi pesantren. Sebagai satuan pendidikan pendidikan MA Al Karimiyah, peran serta pesantren harus dilibatkan dalam semua keputusan yang dibuat oleh satuan pendidikan di bawahnya, misalnya penerapan delapan standar nasional pendidikan. Secara khusus, kepala madrasah MA al-Karimiya tidak hanya harus baik dan akurat, tetapi juga bijaksana dalam mengambil keputusan, dengan mempertimbangkan keterbatasan perspektif, metode dan perspektif yang berbeda, berdasarkan teologis, filosofis, psikologis dan argumen sosiologis Anda harus. MA Al-Karimiya, sebagai perwujudan dari “Al-Muhafadzatu Alal Qodimis Sholih Wal Ahdzu Bil Jadidil Ashhlah”, berupaya mencari tujuan dan metode pendidikan untuk masa depan tanpa meninggalkan tradisi kebaikan masa lalu. Hubungan yang terjalin selama ini merupakan hubungan kekeluargaan yang dikaburkan oleh sistem dan pengetahuan pesantren yang sarat akan nilai-nilai egaliter dengan prinsip sosiologis ' being good is good'.
L’effet de la rémunération monétaire et non monétaire sur la détresse psychologique : le cas du salaire, des augmentations de salaire et de la reconnaissance du superviseur
Authors: Cloutier Julie , Gascon Jacques 
Published: May 2023

L’objectif de cette étude consiste à déterminer dans quelle mesure et de quelle manière les types de rétributions monétaires et non monétaires influencent le niveau de détresse psychologique. Les données ont été collectées auprès de 320 employés provenant d’établissements du secteur des finances et des assurances. Un test de médiation selon la méthode « bootstrap » a été effectué. Les résultats montrent que les perceptions d’équité des rétributions (sécurité d’emploi, salaire, reconnaissance, augmentation de salaire basée sur le rendement) agissent sur la détresse psychologique parce qu’elles signalent aux employés leur valeur (perception de justice distributive). De plus, les rétributions basées sur le rendement agissent également à travers l’interprétation que font les employés des objectifs à atteindre (ex. valeur et estime ; risques d’échec).
Un moteur d’intégration du français à l’échelle nationale : le programme brésilien Idiomes sans frontières (IsF)
Authors: Albuquerque-Costa Heloisa , Zanini Mariza Pereira , Parise Normélia Maria 
Published: May 2023

Les politiques linguistiques et les lois pour l’éducation nationale constituent une scène assez mouvementée au Brésil. Au moment où l’embryon du programme Idiomes sans frontières (IsF) fête sa dixième année, les auteures proposent de passer en revue quelques éléments de cette parcelle de l’histoire, tissant une perspective diachronique qui en révèle quelques lignes de force, fruit de leurs expériences en tant que formatrices de français. Qu’en est-il de la réalité de l’enseignement brésilien depuis les années 1960 ? Que disent les politiques linguistiques sur la place des langues étrangères aux niveaux secondaire et universitaire? Dans quelle mesure le programme IsF, de 2016, peut-il reprendre la perspective plurilingue dans l’enseignement au Brésil ? Quels sont ses limites et ses atouts dans le plan national brésilien ? Pour répondre à ces questions, dans un premier temps, les auteures reviennent sur les directives nationales en matière de langues étrangères dans l’enseignement au Brésil, pour en définir les objectifs et les orientations. Ensuite, le lien est fait avec le programme IsF, qui préconise la reprise du plurilinguisme dans le cadre d’une politique linguistique axée sur l’internationalisation. Pour conclure, elles présentent les perspectives actuelles en ce qui a trait à la formation permanente des futurs enseignants de français dans les universités.
Incidence of Primary End Point Changes Among Active Cancer Phase 3 Randomized Clinical Trials
Authors: Florez Marcus A. , Jaoude Joseph Abi , Patel Roshal R. , Kouzy Ramez , Lin Timothy A. , De Brian , Beck Esther J. , Taniguchi Cullen M. , Minsky Bruce D. , Fuller Clifton D. , Lee J. Jack , Kupferman Michael , Raghav Kanwal P. , Overman Michael J. , Thomas Charles R. , Ludmir Ethan B. 
Published: May 2023

ImportancePrimary end point (PEP) changes to an active clinical trial raise questions regarding trial quality and the risk of outcome reporting bias. It is unknown how the frequency and transparency of the reported changes depend on reporting method and whether the PEP changes are associated with trial positivity (ie, the trial met the prespecified statistical threshold for PEP positivity).ObjectivesTo assess the frequency of reported PEP changes in oncology randomized clinical trials (RCTs) and whether these changes are associated with trial positivity.Design, Setting, and ParticipantsThis cross-sectional study used publicly available data for complete oncology phase 3 RCTs registered in ClinicalTrials.gov from inception through February 2020.Main Outcomes and MeasuresThe main outcome was change between the initial PEP and the final reported PEP, assessed using 3 methods: (1) history of tracked changes on ClinicalTrials.gov, (2) self-reported changes noted in the article, and (3) changes reported within the protocol, including all available protocol documents. Logistic regression analyses were performed to evaluate whether PEP changes were associated with US Food and Drug Administration approval or trial positivity.ResultsOf 755 included trials, 145 (19.2%) had PEP changes found by at least 1 of the 3 detection methods. Of the 145 trials with PEP changes, 102 (70.3%) did not have PEP changes disclosed within the manuscript. There was significant variability in rates of PEP detection by each method (χ2 = 72.1; P &amp;lt; .001). Across all methods, PEP changes were detected at higher rates when multiple versions of the protocol (47 of 148 [31.8%]) were available compared with 1 version (22 of 134 [16.4%]) or no protocol (76 of 473 [16.1%]) (χ2 = 18.7; P &amp;lt; .001). Multivariable analysis demonstrated that PEP changes were associated with trial positivity (odds ratio, 1.86; 95% CI, 1.25-2.82; P = .003).Conclusions and RelevanceThis cross-sectional study revealed substantial rates of PEP changes among active RCTs; PEP changes were markedly underreported in published articles and mostly occurred after reported study completion dates. Significant discrepancies in the rate of detected PEP changes call into question the role of increased protocol transparency and completeness in identifying key changes occurring in active trials.
Uterus‐Derived Decellularized Extracellular Matrix‐Mediated Endometrial Regeneration and Fertility Enhancement
Authors: Ahn Jungho , Sen Tugce , Lee Danbi , Kim Hyeonji , Lee Jae Yeon , Koo Hwa Seon , Kim Jae Yun , Kim Jisoo , Jang Jinah , Kang Youn‐Jung , Cho Dong‐Woo 
Published: May 2023

AbstractTissue‐specific decellularized extracellular matrix recapitulates the complexity of natural ECMs, creating an organ‐specific microenvironment based on its intrinsic characteristics. Here, hydrogels containing uterus‐derived decellularized extracellular matrix (UdECMs) from the endometrium‐specific layer or the entire uterus are developed. UdECMs serve as effective organ‐specific biomaterials, displaying that intrauterine UdECM administration induces endometrial regeneration and fertility enhancement. Moreover, UdECM administration alters the profile of natural killer cell subpopulations to exhibit more mature and less cytotoxic features, providing a favorable uterine environment for successful implantation and decidualization. Interestingly, insulin‐like growth factor 1 and insulin‐like growth factor‐binding protein 3 as key regulatory factors that contribute to UdECM‐mediated endometrial regeneration are discovered. Furthermore, ex vivo culture of human uterine tissues reveals that UdECMs of different origins exhibit distinct therapeutic effects based on the endometrial conditions of patients, suggesting their uses as a therapeutic intervention providing personalized regenerative medicine for infertile patients with a poor uterine environment.
Liquid‐Metal‐Assisted Programmed Galvanic Engineering of Core–shell Nanohybrids for Microwave Absorption
Authors: Zhao Biao , Du Yiqian , Lv Hualiang , Yan Zhikai , Jian Hua , Chen Guanyu , Wu Yuyang , Fan Bingbing , Zhang Jincang , Wu Limin , Zhang David Wei , Che Renchao 
Published: May 2023

AbstractCore–shell nanostructures have received widespread attention because of their potential usage in various technological and scientific fields. However, they still face significant challenges in terms of fabrication of core–shell nanostructure libraries on a controlled, and even programmed scale. This study proposes a general approach to systematically fabricate core–shell nanohybrids using liquid‐metal Ga alloys as reconfigurable templates, and the initiation of a local galvanic replacement reaction is demonstrated utilizing an ultrasonic system. Under ultrasonic agitation, the hydrated gallium oxides generated on the liquid metal droplets, simultaneously delaminated themselves from the interfaces. Subsequently, single‐metal or bimetallic components are deposited on fresh smooth Ga‐based alloys via galvanic reactions to form unique core–shell metal/metal nanohybrids. Controlled and quantitative regulation of the diversity of the non‐homogeneous nanoparticle shell layer composition is achieved. The obtained core–shell nanostructures are used as efficient microwave absorbers to dissipate unwanted electromagnetic wave pollution. The effective absorption bands (90% absorption) of core–shell GaNi and GaCoNi nanohybrids are 3.92 and 3.8 GHz at a thickness of 1.4 mm, respectively. This general and advanced strategy enables the growth of other oxides or sulfides by spontaneous interfacial redox reactions for the fabrication of functional materials in the future.
Anion Receptor Weakens ClO4− Solvation for High‐Temperature Sodium‐Ion Batteries
Authors: Zhou Xunzhu , Chen Xiaomin , Yang Zhuo , Liu Xiaohao , Hao Zhiqiang , Jin Song , Zhang Longhai , Wang Rui , Zhang Chaofeng , Li Lin , Tan Xin , Chou Shu‐Lei 
Published: May 2023

AbstractSodium‐ion batteries (SIBs) with wide operating temperature are regarded as promising candidates for large‐scale energy storage systems. However, SIBs operating under elevated temperature aggravate the electrolyte decomposition with unstable cathode‐electrolyte interphase (CEI), causing a rapid capacity degradation. Herein, anion receptor tris(pentafluorophenyl)borane (TPFPB) is selected as electrolyte additive to construct robust NaF‐rich CEI. The strong interactions between anion and TPFPB via the electron‐deficient boron atoms weaken ClO4− solvation and promote the coordination capability between solvents and Na+ cations, demonstrating greatly improved oxidative stability. Na3V2(PO4)3 cathode in TPFPB‐containing electrolyte delivers long‐term stability with a capacity retention of 86.9% after 100 cycles at a high cut‐off voltage of 4.2 V (vs. Na+/Na) and a high temperature of 60 °C. Besides, TPFPB also works well with enhanced performance over a temperature range from −30 to 60 °C. This study proposes a prospective method by manipulating the solvation chemistry for constructing high‐temperature rechargeable SIBs.