bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bi, Python and Low Code Applications to Accelerate Digital Transformation
Authors: Heine S. , Castillo O. A. , Palacios M. R. , López C. , Castello M. E. , Albarracín H. , Serrano G. D. 
Published: June 2023

Abstract
Citizen developer teams can be a valuable asset to any organization as they can help drive innovation and increase efficiency by quickly building custom solutions to meet specific business needs. They can also help bridge the gap between IT and business teams, allowing for more collaboration and better alignment of technology with business goals.
Overall, citizen developer teams are a way for organizations to tap into the collective knowledge and expertise of their employees, empower them to drive digital transformation and improve business processes.
This presentation aims to illustrate the importance of having such hybrid teams in any organization. By empowering non-technical employees to create custom software solutions, organizations can access a diverse range of knowledge and expertise to meet the needs of all stakeholders. DataGMA exemplifies this approach, having successfully improved data-driven processes at YPF Upstream NOC through the development and implementation of short-term Digital Solutions. By utilizing microservice principles and agile methodologies, DataGMA has made a significant impact on the organization, fostering a culture of data-driven decision making and improving various business processes.
Specifically, DataGMA is a YPF Upstream NOC multidisciplinary team that combines geoscientists with technical support to deliver short-term solutions using Python and Low Code Platforms.
While IT manages main and corporate applications according to corporate priorities and scope, DataGMA can take on new challenges and provide targeted solutions for short-term needs.
Historical data was officially safeguarded and made available through new workflows, via optimized formats. Many manual tasks were replaced by automatic processes and many Python applications were created to optimize the interpretations of physical phenomena, with minimal cost. Finally, work methodologies and reporting of various disciplines were optimized through a combination of dashboards and low code application building.
Throughout 3 years, DataGMA has improved many business processes by tackling non-governed data and building data awareness. This has radically improved engagement around the data life cycle and reduced time of no valuable work, such as repetitive or inefficient tasks. With a dynamic approach, the team was able to solve, not only recurrent business problems but new challenging ones, which has helped with digital transformation transition. DataGMA is an example of how a group of citizen Developers, included in a team with access to digital technologies, can achieve a direct impact on business performance.
Determination of Rock Compressibility in Unconsolidated Sand in Heavy and Extra-Heavy Oil Fields in Mexico
Authors: Fragoso A. , Aguilera R. , Cinco-Ley H. 
Published: June 2023

Abstract
Unconsolidated sands in heavy and extra-heavy oil fields in Mexico have significant potential that has not been fully evaluated yet. Thus, this paper examines petrophysics and geomechanical aspects with a view to estimating rock compressibility. This is important since determining this parameter from cores has proved to be difficult many times as the samples tend to collapse easily during laboratory experiments.
The proposed method uses an empirical correlation for estimating Biot coefficient (Li et al., 2020) and more established geomechanical equations written in such a way as to allow the estimation of several types of compressibilities including: bulk compressibility, uniaxial bulk compressibility, pore compressibility, uniaxial pore compressibility, and pore compressibility under hydrostatic load. The data are loaded on a Pickett plot (1966, 1973) to demonstrate the value of pattern recognition.
There are several intermediate results from calculations leading to the compressibilities mentioned above. These include process speed (ratio of permeability and porosity), pore throat aperture in microns at 35 percent cumulative pore volume (rp35), water saturation (Sw), mercury-air capillary pressure (pc), pore throat apertures (rp) at different water saturations, Biot coefficient (α), Poisson's ratio (PR), shear modulus (G), Young's modulus (YM), and fluid compressibility (cf).
An important observation is that although use of the equations presented in the paper are straight forward and lead to quick calculation of all parameters mentioned above, it is likely that calculations from well logs without using pattern recognition may lead to uncertain results.
The novelty of the paper is developing a methodology for calculating diverse types of rock compressibilities in unconsolidated sandstone reservoirs. Application of the methodology can lead to improved calculated recovery factors of unconsolidated sandstone reservoirs in heavy and extra-heavy oil fields in Mexico by at least 10%.
Fast Real-Time Production Optimization for Integrated Asset Modelling Using Mixed-Integer Non-Linear Programming in Julia Language
Authors: Canchucaja Ramiro 
Published: June 2023

Abstract
This study proposes a method for integrated asset modelling by using machine learning along with operations research algorithms to perform real-time constrained production optimization and maximize operational profit in a real-time basis.
The methodology, which is mainly about the transformation of field and well performance to equations, inequalities, and matrixes, was tested successfully in the operation of a gas condensate field where operational profit increased, in abnormal conditions when personnel normally act mostly based on experience, pre-conceived notion, or solutions to previously solved problems. The study provides a solution with full data-driven objectivity for decision-making using the results of a mixed integer non-linear programming problem.
Going from Days to Hours: A Digital Journey to Optimize Barrels and Improve Work-Life Balance
Authors: Batallas E. , Gallegos J. , Seadi G. Tagarot , Campana D. , Vargas A. , de la Bastida M. A. Hernandez , Florez F. 
Published: June 2023

Abstract
The Choke Model is an approach to determine well potential after considering all the production system constraints. It is designed to identify production losses, network bottlenecks, and optimization opportunities. This paper shares the digital generation of the Choke Model for a mature field. The core components of the model are production potential estimate; production accounting; shortfall accounting and opportunities materialization. The solution leverages the already deployed cloud systems to define the individual choke capacity —reservoir, well, plant, export and, commercial—. A combination of in-house coding and industry-standard software solutions set a new path to add value with digital capabilities and offers.
The solution automated the Asset's choke model using python codes, compiling results in an interactive dashboard with the most frequent —usually daily— updated production potential. The dashboard grouping and analytics allows quick visualization of opportunities, (i.e. workover candidates such as matrix stimulations, hydraulic fractures and reperforation jobs). The impact included rising awarness of capacity constraints along production system, prioritization based on feasible execution; and better work-life balance for team members; with the corresponding monetary surplus.
Friction and Casing Wear Factor Characterization
Authors: Barreto Jose Alberto , Grittini Santiago Javier , Zambetti Raffaello , Zara Emanuel Mariano , Tuckart Walter 
Published: June 2023

Abstract
Casing wear is a concern among O&G operators worldwide since it can lead to well integrity issues. Wear can appear on both elements, drill pipe and the external casing, resulting in the reduction of the tubular wall thickness affecting its performance. To address the topic, a tribometer was developed based on the standard API STD 7CW (2015), including a rotating element that slides against a fixed element while being exposed to drilling mud, leading to the obtention of coefficients of friction (CoF) and casing wear factors, for different combinations of Oil Country Tubular Goods (OCTG).
To estimate CoF and casing wear factors, more than 70 laboratory tests were performed combining steel grades under repetitive and consistent conditions. Contact force was fixed and maintained between both elements during test. CoF were calculated by direct torque measurement, while casing wear factors were indirectly defined by measuring the material loss volume.
Results obtained in CoF were in a range of 0.3 and 0.5, being higher than the values in open literature. They also showed a relation between drill element grades and higher values of CoF. Three zones were detected when evaluating CoF results together. Analyzing casing wear factors, the results obtained were in a range from 0.03 to 0.3 (1/psi E-09), this range is slightly lower than public data available. Different testing conditions such as torque and displacement were evaluated to assess the behavior of 28Cr alloy.
A controlled evaluation of social prescribing on loneliness for adults in Queensland: 8-week outcomes
Authors: Dingle Genevieve A. , Sharman Leah S. , Hayes Shaun , Haslam Catherine , Cruwys Tegan , Jetten Jolanda , Haslam S. Alexander , McNamara Niamh , Chua David , Baker J. R. , Johnson Tracey 
Published: June 2023

Abstract
Background
There have been few controlled evaluations of Social Prescribing (SP), in which link workers support lonely individuals to engage with community-based social activities. This study reports early outcomes of a trial comparing General Practitioner treatment-as-usual (TAU) with TAU combined with Social Prescribing (SP) in adults experiencing loneliness in Queensland.
Methods
114 individuals were non-randomly assigned to one of two conditions (SP, n = 63; TAU, n = 51) and assessed at baseline and 8 weeks, on primary outcomes (loneliness, well-being, health service use in past 2 months) and secondary outcomes (social anxiety, psychological distress, social trust).
Results
Retention was high (79.4%) in the SP condition. Time x condition interaction effects were found for loneliness and social trust, with improvement observed only in SP participants over the 8-week period. SP participants reported significant improvement on all other outcomes with small-to-moderate effect sizes (ULS-8 loneliness, wellbeing, psychological distress, social anxiety). However, interaction effects did not reach significance.
Discussion
Social prescribing effects were small to moderate at the 8-week follow up. Group-based activities are available in communities across Australia, with data here suggesting that they offer accessible and tailored solutions to meet individual psychosocial needs.
Trial registration
ANZCTR, Retrospectively registered 08/06/2022, https://www.anzctr.org.au/ACTRN12622000801718.aspx
Litter isopod mouthpart traits respond to a tropical forest recovery gradient
Authors: Ang Shawn B. H. , Lam Weng Ngai , Png G. Kenny , Tan Sylvia K. B. , Lee Benjamin P. Y-H. , Khoo Max , Luskin Matthew S. , Wardle David A. , Slade Eleanor M. 
Published: June 2023

Abstract
Functional trait ecology has the potential to provide generalizable and mechanistic predictions of ecosystem function from data of species distributions and traits. The traits that are selected should both respond to environmental factors and influence ecosystem functioning. Invertebrate mouthpart traits fulfil these criteria, but are seldom collected, lack standardized measurement protocols, and have infrequently been investigated in response to environmental factors. We surveyed isopod species that consume plant detritus, and tree communities in 58 plots across primary and secondary forests in Singapore. We measured body dimensions (body size traits), pereopod and antennae lengths (locomotory traits), dimensions of mandible structures (morphological mouthpart traits), and mechanical advantages generated by mandible shape (mechanical mouthpart traits) for six isopod species found in these plots and investigated if these traits respond to changes in tree community composition, tree diversity, and forest structure. Morphological mouthpart traits responded to a tree compositional gradient reflecting forest recovery degree. Mouthpart features associated with greater consumption of litter (broader but less serrated/rugose lacinia mobilis [an important cutting and chewing structure on the mandible]) were most prevalent in abandoned plantation and young secondary forests containing disturbance-associated tree species. Feeding strategies associated with fungi grazing (narrower and more serrated/rugose lacinia mobilis) were most prevalent in late secondary forests containing later successional tree species. Since morphological mouthpart traits likely also predict consumption and excretion rates of isopods, these traits advance our understanding of environment–trait–ecosystem functioning relationships across contrasting tropical forest plots that vary in composition, disturbance history and post-disturbance recovery.
The “Look! - your baby is talking to you” intervention study aiming to reduce post-partum depressive symptoms among vulnerable mothers: A process evaluation.
Authors: Ejlertsen Camilla , Kristensen Ingeborg Hedegaard , Voltelen Barbara , Brødsgaard Anne 
Published: June 2023

Abstract

Background: A successful early parent-infant interaction may be threatened by maternal anxiety or depression. The obstetric department's healthcare professionals are in a unique position to initiate early intervention. Early interventions and short-term programmes aiming to improve mother-infant interaction have shown to be successful. This study aimed to evaluate the intervention study “Look! – Your baby is talking to you” with the primary aim of lowering maternal postnatal depression symptoms three months after birth. The intervention adopted a relationship-based approach in a family-oriented context and aimed to optimise transition to primary healthcare for vulnerable families. The intervention components included the Newborn Behavioral Observations System, family-focused nursing, and a systematic transition to primary healthcare.
Methods: By examining implementation, i.e., reach, dose, fidelity, and mechanisms of impact of the intervention "Look! – Your baby is talking to you", we evaluated the intervention study using the UK Medical Research Council process evaluation framework. The contextual considerations and adaptations made to ensure implementation were in focus of the evaluation.
Results: The intervention “Look! – your baby is talking to you” reached the intended target group of vulnerable mothers with previous or current depression and/or anxiety. In the intervention group, 47 women completed the follow-up questionnaires; in the non- intervention group, 51 women responded to the questionnaires. The intervention dose was delivered as intended with high fidelity, proving that the healthcare professionals increased knowledge, intention, skills, and self-efficacy in relation to postnatal care after Newborn behavioural observation training. Mechanisms of impact reflected mixed effect results. However, both the primary (maternal depressive symptoms) and the secondary outcomes (maternal stress, reflective function, and family function) tended to favour the intervention group.
Conclusion: Overall, the intervention was applicable to clinical practice. It was feasible and had high participation. Furthermore, the process evaluation revealed potential facilitators and barriers to the targeted processes, which is essential knowledge for future evaluation of the effects of the intervention.
Trial registration:
ClinicalTrials.gov ID: NCT04169334, Registered 19 November 2019.
Neurosyphilis presenting with Guillain-Barre Syndrome: A Case Report
Authors: Ung Hoameng , Ferrey Dominic 
Published: June 2023

Abstract
Background
Syphilis is associated with a wide variety of different systemic presentations, earning it the moniker “The great mimicker”. Neurosyphilis is classically associated with meningovasculitis in the acute-subacute stage and tabes dorsalis and dementia paralytica in later stages. However, one of the less well described presentations includes Guillain-Barre Syndrome. This case presents a patient with neurosyphilis who developed with an ascending polyneuropathy with electrodiagnostic testing consistent with demyelination, supporting a diagnosis of neurosyphilis associated Guillain-Barre Syndrome.
Case presentation
A 37-year-old female presented to the emergency department with a weakness and difficulty swallowing. She described a three-month history of symptoms, initially starting with a persistent headache followed by one month of a pruritic rash on her chest, palms, and soles. Two weeks ago, she developed weakness in her arms, numbness in her arms and chest, and for the last two days, difficulty swallowing. Neurological exam was notable for multiple cranial neuropathies, distal greater than proximal upper and lower extremity weakness, length-dependent sensory loss, and hyporeflexia. Investigation revealed a positive Venereal Disease Research Laboratory in her cerebrospinal fluid without pleocytosis, contrast enhancement in cranial nerve V, VII, and VIII on MRI, and a demyelinating polyneuropathy on electrodiagnostic testing. She was diagnosed with Guillain-Barre syndrome, secondary to neurosyphilis. The patient acutely declined and required intubation, and ultimately made a full recovery after treatment with plasmapheresis and penicillin.
Conclusions
This case describes a clinical entity of syphilitic Guillain-Barre Syndrome and highlights the importance of including syphilis in the differential of a patient presenting with ascending polyradiculopathy, especially given the resurgence of syphilis.
Metabolic composition of endophytes contributed to the effect of Brassica rapa L. in improving immunity
Authors: Wei Jie , Wu Jianyong , Wei Yurong , Yimiti Dlixiati , Mi Xiaoyun 
Published: June 2023

Abstract
Background.
As a medicinal plant, Brassica rapa L. contains various valuable metabolites and endophytes, and has been widely used in Northwest China. However, the detailed contributions of endophytes to the mechanisms of Brassica rapa L. improving immunity were still unknown. Previously, we isolated four endophyte fungi from Brassica rapa L..
Methods.
In this study, we identified the effect of endophytes of metabolites of Brassica rapa L. and its extracts in improving immunity through triggering genes relevant to NF-kB and inflammatory pathways. Then, we performed GC-MS metabolomics to analyze the metabolic variations among these four endophytes.
Results.
The results showed that the metabolic compositions of PR10 significantly varied from other three endophytes. PR10 is rich in amino acids, which may affect amino acids compositions of Brassica rapa L.. And the PR10 extracts highly activated genes involved in NF-κB and inflammatory pathways, reaching a consensus with the effect of Brassica rapa L.. And the dominant metabolites of PR10 were also closely associate with various diseases, including pyruvate dehydrogenase deficiency, Heart failure and various Inflammatory diseases. Thus, Brassica rapa L. may improve the inflammatory-related diseases and immunity through its specific metabolic compositions associated with endophyte PR10. Typically, trehalose was the main metabolites that made contributions to the immune-promotion effects of PR10 and Brassica rapa L.. In conclusion, metabolites highly produced by PR10 explained the medicinal value of Brassica rapa L. in improving immunity.
Continuous nerve block versus thoracic epidural analgesia for post-operative pain of pectus excavatum repair: A systematic review and meta-analysis
Authors: Chen Li-Jung , Chen Shih-Hong , Hsieh Yung-Lin , Yu Po-Chuan 
Published: June 2023

Abstract
Surgery to repair pectus excavatum (PE) is often associated with severe postoperative pain, which can impact the length of hospital stay (LOS). While thoracic epidural analgesia (TEA) has traditionally been used for pain management in PE, its placement can sometimes result in severe neurological complications. Recently, paravertebral block (PVB) and erector spinae plane block (ESPB) have been recommended for many other chest and abdominal surgeries. However, due to the more severe and prolonged pain associated with PE repair, it is still unclear whether continuous administration of these blocks is as effective as TEA. Therefore, we conducted this systematic review and meta-analysis to demonstrate the equivalence of continuous PVB and ESPB to TEA.
Broadly neutralizing antibodies against Zika virus from dengue patients with prior exposure to Japanese encephalitis virus
Authors: Salem Gielenny , Galula Jedhan , Wu Shang-Rung , Liu Jyung , Chen Yen-Hsu , Wang Wen-Hung , Wang Sheng-Fan , Song Cheng-Sheng , Chen Fan-Chi , Wang Cheng-Yi , Chao Day-Yu 
Published: June 2023

Abstract
Exposure to multiple mosquito-borne flaviviruses within a lifetime is not uncommon; however, how sequential exposures to different flaviviruses shape the cross-reactive (CR) humoral response against an antigen from a different serocomplex has yet to be explored. Here, we report that dengue-infected individuals initially primed with the Japanese encephalitis virus (JEV) showed broadly highly neutralizing potencies against the Zika virus (ZIKV). We also identified a rare class of ZIKV CR human monoclonal antibodies (huMAbs) with increased somatic hypermutation and broad neutralization against multiple flaviviruses. One huMAb, K8b, binds quaternary epitopes with heavy and light chains separately interacting with overlapping E dimer units spanning domains I, II, and III through cryo-electron microscopy and structure-based mutagenesis. Using JEV virus-like particle (VLP) immunization in mice further confirmed that such CR antibodies, mainly IgG3 isotype, can be induced and proliferate through heterologous DENV-2 VLP stimulation. Our findings provide novel insights for future vaccination strategies.