bluuebunny/crossref_metadata_2025_split huggingface dataset:
Direct and indirect associations of experience of racial discrimination, dietary patterns and obesity in adults from southern Brazil
Authors: Fanton Marcos , Rodrigues Ylana , Schuch Ilaine , Cunha Caroline Marques de Lima , Pattussi Marcos Pascoal , Canuto Raquel 
Published: July 2023

Abstract

Objective: the study aimed to analyze the direct and indirect associations of self-reported experience of racial discrimination with dietary patterns, obesity, and abdominal obesity.
Design: it is a cross-sectional population-based study. The main exposure was self-reported experiences of racial discrimination which was assessed by the Experiences of Discrimination scale. The mediator variables were the dietary patterns: healthy, traditional Brazilian, refined carbohydrates and sugars, and fast food. The outcomes were obesity (body mass index ≥30 kg/m²), and abdominal obesity (waist circumference ≥ 88 cm for women and ≥ 102 cm for men). Structural equation modeling was used to clarify relationships between exposures, outcomes and mediating variables.
Setting: Porto Alegre, Brazil
Participants: 400 adults aged between 20 and 70 years.
Results: the mean age of participants was 47.2 years (SD = 13.9 years). Experience racial discrimination had a positive direct effect on obesity and abdominal obesity in all models. The experience of racial discrimination did not have a direct effect on any dietary pattern neither the experience of racial discrimination did not have an indirect effect on obesity and abdominal obesity via any dietary pattern.
Conclusions: our results suggest that a higher experience of racial discrimination is associated with obesity and abdominal obesity, and its association is independent of healthy or unhealthy dietary patterns.
Expression level of microRNA-574-5p and its association with inflammatory cytokines and disease severity in Rheumatoid Arthritis
Authors: xing yida , liu changyan , liu xiaoyan , wu qiyuan , zheng fneg , kong xiaodan 
Published: July 2023

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized with aggressive arthritis, accompanied by extra articular and systemic manifestations. The pathogenesis of RA is still unclear. MicroRNA (miRNA) is single stranded, noncoding, small molecule RNA that is actively involved in inflammatory diseases and may play a role in RA. A prospective cohort study involving 66 patients with RA and 16 normal controls (NC) was conducted. All patients （49 females and 17 males）were divided into three groups （low disease activity 21/66, moderate disease activity 18/66, high disease activity 27/66）based on DAS28-ESR. The expression of miR-574-5p and the concentration of proinflammatory cytokines TNF-α, IL-1β and IL-6 in serum of the patients and normal controls were detected. Compared with the NC, the serum levels of miR-574-5p, TNF-α, IL-1β and IL-6 were significantly increased (P < 0.05). In addition, the fold of increase was correspondent to the level of disease activity. Moreover, the expression of miR-574-5p appeared to correlate to the concentration of individual cytokine. The expression of miR-574-5p in the serum of patients with RA was correlated with disease activity and proinflammatory cytokines, suggesting that it may be involved in the pathogenesis of RA.
Prediction of self-healing properties of concrete modified with bacteria and fibers using Machine Learning
Authors: Pessoa Carolina Emerenciana , Silva Victor Hugo Peres , Stefani Ricardo 
Published: July 2023

Abstract
Self-healing concrete has been studied as an alternative material to overcome problems such as cracking and low durability of conventional concrete. However, laboratory experiments can be costly and time-consuming. Hence, Machine Learning algorithms can assist the development of better formulations for self-healing concrete. In this work, Machine Learning (ML) models were developed using Multiple Linear Regression (MLR), Support Vector Machine (SVM) and Random Forest Regressor (RF) to predict and analyze the repairing rate of the cracked area of self-healing concretes containing bacteria and fibers in their formulations. The results show that the Radial-Basis (RBF) SVM (R2 = 0.927, MAE = 0.053 and RMSE = 0.004) and RFG (R2 = 0.984, MAE = 0.019, RMSE = 0.000) algorithms performed better in predictions and delivered better-fitted models. Therefore, RF regressor and RBF SVM models can be applied to develop and validate high performance self-healing concrete formulations based on polymeric fibers and bacteria.
Research of phenolic compounds content in yoshta berries for the perspective of cultivation and use in healthy nutrition in the steppe zone of Ukraine
Authors: Lykholat Olena , Khromykh Nina , Lykholat Tetyana , Didur Oleh , Kvitko Maksim , Lykholat Yuriy 
Published: July 2023

Unfavourable socio-economic conditions and unbalanced nutrition, expressed in the deficiency of biologically active substances, determine the need to use fruit crops as a source of biologically active substances. In world practice, priority is given to fruit plants that have biological activity useful for the human body. The relevance of the concept of balanced natural nutrition is increasing with the growth of the global population. Products containing pesticides, preservatives, artificial colors and flavors or other chemicals are included in the "black" list of all natural food advocates.
Jošta fruits is a low-calorie berry, 100 g of berries contain only 45‒48 calories. Nutritional value of yoshta (per 100 g of product): carbohydrates ‒ 9.1 g; fats ‒ 0.2 g; proteins ‒ 0.7 g; water ‒ 80 g. Jošta fruits contains vitamin C (ascorbic acid) in large quantities, vitamin P (rutin), pectin substances, phytoncides, organic acids, sugar, anthocyanins, potassium, iron, iodine, copper, etc. And the anthocyanins included in its composition accelerate metabolic processes and are capable of breaking down fats. Pectins improve and normalize intestinal microflora, which in turn contributes to cleansing. The aim of the work was the study of Jošta plant as a promising species for further possible ecological diversity of the territory of the right bank of the Dnieper in Ukraine.
The rare currant-gooseberry hybrid Jošta plant can be recommended for growing and using fruit products in functional human nutrition. The Jošta can be recommended for the cultivation and use of fruit products in functional human nutrition and, in particular, in the restaurant business namely locavores for the presentation of the author's intellectual interpretation of local products
THE EFFECT OF SURVIVOR’S BENEFITS ON WOMEN’S EMPLOYMENT: AN EXAMPLE IN TURKEY
Authors: ŞAHİN KESKİN Gülnaz , ÇAVLİN Alanur 
Published: July 2023

Türkiye'de kadın istihdamı erkek istihdamının gerisindedir. Literatürdeki çalışmalar eğitim durumu, yaş, tarımsal çözülme, aile içi sorumluluklar, çocuk ve yaşlı bakımının kurumsal yetersizliği gibi nedenlerle kadın istihdamının erkek istihdamından düşük olduğuna dair hipotezler içermektedir. Ancak kadınlara doğrudan yapılan sosyal yardımların kadınların istihdamlarına ve kayıtlı ekonomiye entegre olmalarına etkisini ölçen çalışma yok denecek kadar azdır. İşte bu çalışma ile ailede çalışan kişinin vefatı halinde geride kız çocuklara bağlanan dul ve yetim aylıklarının hem kadınların istihdamlarına hem de kayıtlı istihdamlarına etkisi ölçülmektedir.
Hayatta kalanlar için emeklilik maaşları, ailede aktif olarak sigortalı çalışan kişinin erkek olduğu, erkek çocukların yetişkin olduklarında işgücü piyasasına girmeleri gerektiği ve kadınların çalışmak zorunda olmadıkları anlayış ile düzenlenmiştir. Böylece kadınlar bu emekli maaşlarını neredeyse hayatları boyunca bir tür kadın emekli maaşı olarak almaktadırlar. Çalışmada Gelir ve Yaşam Koşulları Araştırması, 2017 yılı verisi birincil kaynak, Sosyal Güvenlik Kurumu 2020 verisi ise ikincil kaynak olarak kullanılmıştır. Sonuçta, kadınlara yetim aylıklarında yapılan pozitif ayrımcı uygulamaların onları kayıtlı istihdamdan alıkoyan özelliği olduğu ve bu yönünün sosyo-ekonomik politikalarla bertaraf edilmesi gerektiği kanaatine varılmıştır.
Hydrochemical characterisation and identification of seawater intrusion in the Visakhapatnam coastal aquifer
Authors: Mythilee Priyanka Venna , Maddamsetty Ramesh , Yarramalle Srinivas 
Published: July 2023

Abstract

Groundwater dependency has increased due to several factors like population increase, industrialization, and climate change impact. Analysis of groundwater is important to know the present status and also for better management of natural resources. Groundwater samples from 41 locations were collected along the study area during the pre and post-monsoon seasons, and samples were analysed for pH, EC, total dissolved solids (TDS), major cations, and anions like Ca2+, Mg2+, Na+, K+, Cl−, HCO3− and SO42−. From the chemical analysis results, seawater intrusion is identified through qualitative approaches, i.e., Simson ratio (Cl/(HCO3 + CO3) and Na/Cl ratio. Simson ratio ranges between 0.316 to 2.119 during pre-monsoon and 0.124 to 3.947 during post-monsoon, and from Na/Cl ratio, 30 samples fell under seawater intrusion during pre-monsoon and 38 samples during post-monsoon. The Simpson ratio results also show that seawater intrusion is reducing during the post-monsoon due to increasing groundwater levels caused by rains. From the water quality index classification, 4.88% of the water samples fell under excellent in both seasons, and the rest of the samples were all in the remaining four classes. The spatial analysis was also done to understand the changes in groundwater quality and seawater intrusion over space.
Ethical behavior in the work environment and its effects on academic misconduct
Authors: Anzilago Marcielle , Daciê Franciele do Prado , Giustina Kelly Arent Della 
Published: July 2023

Objective: This study aims to analyze the effects that ethical behavior in the work environment has on attitudes towards cheating in the academic environment among accounting sciences students.
Methodology: A survey was carried out with students from a public HEI, totaling 140 participants. For data analysis, structural equations and factorial analysis were used as technique.
Results: The findings show that, in addition to ethical behavior in the workplace, there are other variables that lead students to have academically dishonest attitudes. In this way, ethical behavior influences the unethical behavior of accounting students at the HEI studied, and, although with still small effects, the experiences lived and taken as ethical in the professional environment tend to be related to an evasion of dishonest attitudes in the academic sphere, that is, a better corporate ethical rank results in a smaller presence of cheating behaviors in academia.
Study Contributions: The study contributes to reflection on the improvement of students' behavior in the work environment and how this affects the academy, showing the importance of discussing ethics in professional and educational environments. It reveals the importance of ethics not only in the academic environment, but also in the business environment, so that there is a convergence between both.
Exploring the Mechanism of Si-miao-yong-an Decoction in the Treatment of Coronary Heart Disease based on Network Pharmacology and
Experimental Verification
Authors: Zhang Jingmei , Xue Siming , Chen Huan , Jiang Haixu , Gao Pengrong , Lu Linghui , Wang Qiyan 
Published: July 2023

Background:
To investigate the active ingredients and the mechanisms of Si-miaoyong-
an Decoction (SMYA) in the treatment of coronary heart disease (CHD) by using network
pharmacology, molecular docking technology, and in vitro validation.

Methods:
Through the Chinese Medicine System Pharmacology Database and Analysis Platform
(TCMSP), Uniprot database, GeneCards database, and DAVID database, we explored the core
compounds, core targets and signal pathways of the effective compounds of SMYA in the treatment
of CHD. Molecular docking technology was applied to evaluate the interactions between active
compounds and key targets. The hypoxia-reoxygenation H9C2 cell model was applied to carry
out in vitro verification experiments. A total of 109 active ingredients and 242 potential targets
were screened from SMYA. A total of 1491 CHD-related targets were retrieved through the Gene-
Cards database and 155 overlapping CHD-related SMYA targets were obtained. PPI network topology
analysis indicated that the core targets of SMYA in the treatment of CHD include interleukin-
6 (IL-6), tumor suppressor gene (TP53), tumor necrosis factor (TNF), vascular endothelial
growth factor A (VEGFA), phosphorylated protein kinase (AKT1) and mitogen-activated protein
kinase (MAPK). KEGG enrichment analysis demonstrated that SMYA could regulate Pathways in
cancer, phosphatidylinositol 3 kinase/protein kinase B (PI3K/Akt) signaling pathway, hypoxiainducible
factor-1(HIF-1) signaling pathway, VEGF signaling pathway, etc.

Results:
Molecular docking showed that quercetin had a significant binding activity with VEGFA
and AKT1. In vitro studies verified that quercetin, the major effective component of SMYA, has a
protective effect on the cell injury model of cardiomyocytes, partially by up-regulating expressions
of phosphorylated AKT1 and VEGFA.

Conclusion:
SMYA has multiple components and treats CHD by acting on multiple targets. Quercetin
is one of its key ingredients and may protect against CHD by regulating AKT/VEGFA pathway.
The Effect of Dexamethasone on Lipopolysaccharide-induced Inflammation
of Endothelial Cells of the Blood-brain Barrier/Brain Capillaries
Authors: Jeftha Tershlin , Makhathini Khayelihle Brian , Fisher David 
Published: July 2023

Background:
A protective and regulatory barrier between the blood and the brain is
constituted by the blood-brain barrier (BBB), which comprises microvascular endothelial cells
providing homeostatic regulation of the central nervous system (CNS). Inflammation compromises
the BBB and contributes to many CNS disorders. Anti-inflammatory effects are exerted by glucocorticoids
(GCs) on a variety of cells. These GCs include dexamethasone (Dex), which is used for
the treatment of inflammatory diseases and recently for the treatment of COVID-19.

Aim:
The purpose of this study was to determine whether low or high concentrations of Dex can attenuate
the inflammatory response induced by lipopolysaccharide (LPS) in the in vitro BBB model.

Methods:
Brain endothelial cells (bEnd.5) were cultured and exposed to LPS (100ng/ml) and subsequently
co-treated with Dex to investigate whether selected concentrations of Dex (0.1, 5, 10,
20μM) can modulate the inflammatory effects of LPS on bEnd.5 cells. Cell viability, cell toxicity,
and cell proliferation were investigated, as well as the monitoring of membrane permeability (Trans
Endothelial Electrical Resistance-TEER), and Enzyme-Linked Immune Assay (ELISA) kits were
used to identify and quantify the presence of inflammatory cytokines (TNF-α and IL-1β).

Results:
Dex, at a lower dosage (0.1μM, but not higher doses), was able to attenuate the inflammatory
effects of LPS on bEnd.5 cells. Lower doses of Dex (0.1μM) had no detrimental effects on
bEnd.5 cells, while higher Dex doses (5-20μM) decreased bEnd.5 viability, increased bEnd.5 cell
toxicity, increased bEnd.5 cell monolayer permeability, and increased proinflammatory cytokine
secretion.

Conclusion:
These results indicate that treatment of brain vascular inflammation with low doses of
Dex should be advocated, while higher doses promote vascular inflammation.
Aplikasi Biometric Untuk Membantu Identifikasi Wanita Bercadar
Authors: Achmad Dhimas Herdiyansyah  , Akhmad Rizal Dzikrillah  
Published: July 2023

Pada saat ini terdapat beberapa permasalahan tentang penggunaan niqab atau cadar, mulai dari masalah pelarangan penggunaan cadar di beberapa instansi dan adanya penyalahgunaan cadar atau niqab (Crosshijaber) yang dimanfaatkan untuk melakukan tindakan tidak terpuji ataupun tindakan kriminal. Berdasarkan permasalahan diatas serta hasil wawancara yang dilakukan dapat disimpulkan bahwa dibutuhkan suatu sistem untuk memfasilitasi para pengguna cadar atau niqab serta membantu sebuah instansi terkait dalam melakukan identfikasi terhadap pengguna tersebut. Penelitian ini dilakukan di Universitas Muhammadiyah Prof. DR HAMKA di Jakarta, dimana nantinya hasil penelitian ini akan menghasilkan sistem aplikasi biometric dengan harapan aplikasi yang telah dibangun ini dapat memfasilitasi mahasiswi yang menggunakan cadar atau niqab serta mempermudah instansi Universitas Muhammadiyah Prof. DR HAMKA melakukan identifikasi terhadap pengguna cadar tersebut sehingga tidak terjadi penyalahgunaan. Perancangan ini menggunakan metode waterfall, dengan bahasa pemrograman Java dan MySQL sebagai databasenya. Hasil wawancara dan penyebaran kuisioner kepada user menunjukkan bahwa aplikasi biometric dapat membantu mengidentifikasi wanita bercadar tanpa harus membuka cadar atau niqabnya, sehingga dapat disimpulkan bahwa aplikasi ini dapat mempermudah dan membantu dalam meningkatkan keamanan baik untuk Instansi maupun pengguna cadar.
Alguns desdobramentos sobre os quatro regimes da imagem
Authors: Hussak Pedro 
Published: July 2023

Este texto retoma as questões desenvolvidas no texto Quatro regimes da imagem: ilusória, encarnada, dialética e xamânica, publicado no dossiê Sonho, mercadoria, mundo: três hipóteses para pensar “A queda do céu” na revista La furia umana, buscando responder a algumas críticas e observações levantadas por interlocutores. Trata-se de um esforço de classificação visando à caracterização de quatro tipos de imagem: a imagem ilusória; a imagem encarnada; a imagem dialética e a imagem xamânica. Cada regime da imagem é pensado a partir de polos de tensão que o caracteriza, a saber, a relação entre o visível e o invisível, entre a imagem e o texto e entre a imagem e a verdade.
JUDICIALIZAÇÃO DA SAÚDE E TEORIA DOS SISTEMAS SOCIAIS
Authors: Day Carrilho Bentes Lobato Ribeiro Krishina , Cavalcante Lima Leandro 
Published: July 2023

A complexidade da judicialização da saúde abre espaço à matriz de investigação sistêmica. Qual o estado da arte dos estudos sobre judicialização pela abordagem da Teoria dos Sistema Sociais de Niklas Luhmann? Os objetivos deste estudo são identificar a percepção do fenômeno e a compreensão de seus efeitos e indicar as lacunas da área. Fez-se uma revisão narrativa da literatura, levantada nos sites Scielo, Lilacs e Google Acadêmico com os termos “Judicialização da Saúde” AND “Teoria de Sistemas”. A análise foi diagramada em quadros conceituais utilizando as categorias teóricas complexidade; autorreferencialidade; acoplamento estrutural; comunicação e tomada de decisão. O principal resultado é a identificação da judicialização como uma sobrecarga do sistema judicial, marcado por seu fechamento operativo. Como contribuição se apresenta a formulação das lacunas de pesquisa: a natureza sistêmica da judicialização, o levantamento de evidências empíricas, o parâmetro sobre o fenômeno por região e a metodologia de observação sistêmica.
Keefektifan Konseling Kelompok Dengan Teknik Penguatan Positif Dalam Menurunkan Prokrastinasi Siswa
Authors: Nelasari  , Hartanti Jahju , Farid Dimas Ardika Mifta 
Published: July 2023

The research aims to test counseling groups with technique strengthening procrastination student learning in class XI at senior high school of Dr. Soetomo Surabaya. Procrastination is an events conducted students in suspend work. Counseling groups were done to a counselor as conferring with konseli.Positive form of behavior and strengthening is predicted by students.Used samples from 6 research students given treatment for 7 meetings with significant changes students. From the pretest and posttest used test wilcoxon to indicate that a decline in prokrastinasi student learning where the averages for each pretest is 121.38 and posttest is 88 , because significance = P < 0.05. Thus can be concluded that counseling group to technique strengthening positive impact on prokrastinasi student learning class xi high school dr .Soetomo Surabaya. Keywords: Procrastination, Positif Reinforcement, Group Counseling
Utilization of Aloe Vera Extract as A Natural Coagulant and its Effect on The Characteristics of IRR 118 Clone Rubber
Authors: Achmad Feerzet , Deviany Deviany , Aditya Fajri , Oktasari Anggi , Suhartono Suhartono , Suharto Suharto 
Published: July 2023

Rubber is one of the plantation products as a foreign exchange earner for the country. The process of processing rubber requires coagulants to accelerate coagulation. Aloe vera is a plant that contains compounds of organic acids, is expected to be able to accelerate the coagulation process. The purpose of this study was to determine the effect of the use of natural coagulants of aloe vera extract on the characteristics of IRR 118 clone rubber. The variations of the extracts used are natural coagulant extracts of aloe centrifugation and no centrifugation and the chemical coagulant format acid 3% as a comparison. Centrifugation of natural coagulant extract of aloe vera is carried out at a speed of 3000 rpm for 1 hour. The characterization of rubber analyzed was DRC (Dry Rubber Content), Po (Initial Plasticity), PRI (Plasticity Retention Index), ash content, evaporating substance content, mooney viscosity, dirt content, and nitrogen content. From the results of the study, it was obtained that the percentage of DRC, Po, PRI, and Mooney Viscosity was highest in AV natural coagulants without centrifugation, namely 28%, 36%, 80%, and 80%. The lowest percentage of ash, dirt and nitrogen content in natural coagulants of AV centrifugation was 0.38%, 0.014%, and 0.36%. Aloe vera natural coagulants without centrifugation and centrifuged ones can be used as coagulants for the latex coagulation process because they have met all the requirements of SNI SIR 20 and can be used as natural coagulants.
Isolated Blunt Pancreatic Trauma: A Case of Spleen Preserving Distal Pancreatectomy and One-Stage Pancreaticoduodenectomy
Authors: Molaoa Stephen , Malongwe Siyabonga , Mpikashe Mvuyisi , Desemele Yamkela , Odunze Samuel 
Published: July 2023

Isolated blunt pancreatic injuries are rare. Diagnosis is often delayed due to minimal symptoms and signs. Elevated serum amylase or lipase levels on routine pre-operative laboratory investigations makes pancreatic injury highly likely. Contrast Enhanced CT scan is usually confirmatory.
We are reporting on two patients who presented with blunt abdominal trauma, haemodynamically stable, and with epigastric tenderness. Pre-admission biochemical investigations revealed elevated serum amylase. CECT demonstrated Grade III and Grade IV injuries which were treated with spleen-preserving distal pancreatectomy and pancreaticoduodenectomy, respectively. Post-operatively, both developed amylase-rich fistulae which resolved on conservative management.