bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic response of 3D printed functionally graded sandwich foams
Authors: Bonthu Dileep , H.S. Bharath , Bekinal Siddappa I. , Jeyaraj P. , Doddamani Mrityunjay 
Published: September 2023

Purpose
The purpose of this study was to introduce three-dimensional printing (3DP) of functionally graded sandwich foams (FGSFs). This work was continued by predicting the mechanical buckling and free vibration behavior of 3DP FGSFs using experimental and numerical analyses.

Design/methodology/approach
Initially, hollow glass microballoon-reinforced high-density polyethylene-based polymer composite foams were developed, and these materials were extruded into their respective filaments. These filaments are used as feedstock materials in fused filament fabrication based 3DP for the development of FGSFs. Scanning electron microscopy analysis was performed on the freeze-dried samples to observe filler sustainability. Furthermore, the density, critical buckling load (Pcr), natural frequency (fn) and damping factor of FGSFs were evaluated. The critical buckling load (Pcr) of the FGSFs was estimated using the double-tangent method and modified Budiansky criteria.

Findings
The density of FGSFs decreased with increasing filler percentage. The mechanical buckling load increased with the filler percentage. The natural frequency corresponding to the first mode of the FGSFs exhibited a decreasing trend with an increasing load in the pre-buckling regime and an increase in post-buckled zone, whereas the damping factor exhibited the opposite trend.

Originality/value
The current research work is valuable for the area of 3D printing by developing the functionally graded foam based sandwich beams. Furthermore, it intended to present the buckling behavior of 3D printed FGSFs, variation of frequency and damping factor corresponding to first three modes with increase in load.
Cocaine history and impulsiveness in professional boxers and mixed martial arts fighters
Authors: Young Lisa , Esagoff Aaron I. , Reisch Anne , Bernick Charles B. , Peters Matthew E. , Narapareddy Bharat R. 
Published: September 2023

AbstractBackground/ObjectivesImpulsiveness is linked to cocaine history (CH) in the general population and greater fight exposure in professional fighters. Among fighters, no previous studies have quantified CH or investigated its relationship with impulsiveness.MethodsAdjusted multivariable regressions were utilized to examine the relationship between CH and impulsiveness in 335 fighters from the Professional Fighters Brain Health Study.ResultsTwenty percent of fighters reported CH. CH was significantly associated with impulsiveness overall and on three subscales.Discussion/ConclusionCocaine's prevalence and significant association with impulsiveness in fighters merit further study.Scientific SignificanceWe quantify CH and demonstrate its significant association with impulsiveness in professional fighters for the first time.
Repeated COVID‐19 vaccination to maximum antibody response yields very low mortality and hospitalisation rates in patients with CLL and MBL
Authors: Shen Yandong , Freeman Jane A. , Kerridge Ian , Downe Paul , Naidu Kartik , Holland Juliette , Mulligan Stephen P. 
Published: September 2023

SummaryWe analysed COVID‐19 infection outcomes of 129/241 chronic lymphocytic leukaemia (CLL) (53.9%) and 22/55 monoclonal B‐lymphocytosis (MBL) (40.0%) patients following multiple vaccine doses aiming for maximum measured anti‐spike antibody response. Throughout the pandemic to date, there were 8/129 CLL (6.2%) patients hospitalised, with one death (0.8%). No MBL patients were hospitalised or died. CLL patients with COVID‐19 had lower anti‐spike levels (3778.8 AU/mL) than those without (13 486.8 AU/mL; p = 0.0061). Anti‐nucleocapsid antibody was detected in 29.8% within 2 months and 17.5% >6 months. Of COVID‐19‐infected CLL patients, 47.3% received anti‐viral therapy. A multiple vaccine dosing strategy to achieve measured maximum antibody is highly effective in preventing severe COVID‐19.
Functional alterations in resting‐state networks for Theory of Mind in Parkinson's disease
Authors: Rabini Giuseppe , Funghi Giulia , Meli Claudia , Pierotti Enrica , Saviola Francesca , Jovicich Jorge , Dodich Alessandra , Papagno Costanza , Turella Luca 
Published: September 2023

AbstractIn Parkinson's disease (PD), impairment of Theory of Mind (ToM) has recently attracted an increasing number of neuroscientific investigations. If and how functional connectivity of the ToM network is altered in PD is still an open question. First, we explored whether ToM network connectivity shows potential PD‐specific functional alterations when compared to healthy controls (HC). Second, we tested the role of the duration of PD in the evolution of functional alterations in the ToM network. Between‐group connectivity alterations were computed adopting resting‐state functional magnetic resonance imaging (rs‐fMRI) data of four groups: PD patients with short disease duration (PD‐1, n = 72); PD patients with long disease duration (PD‐2, n = 22); healthy controls for PD‐1 (HC‐1, n = 69); healthy controls for PD‐2 (HC‐2, n = 22). We explored connectivity differences in the ToM network within and between its three subnetworks: Affective, Cognitive and Core. PD‐1 presented a global pattern of decreased functional connectivity within the ToM network, compared to HC‐1. The alterations mainly involved the Cognitive and Affective ToM subnetworks and their reciprocal connections. PD‐2—those with longer disease duration—showed an increased connectivity spanning the entire ToM network, albeit less consistently in the Core ToM network, compared to both the PD‐1 and the HC‐2 groups. Functional connectivity within the ToM network is altered in PD. The alterations follow a graded pattern, with decreased connectivity at short disease duration, which broadens to a generalized increase with longer disease duration. The alterations involve both the Cognitive and Affective subnetworks of ToM.
Archaeology in Botswana's history
Authors: Thebe Phenyo Churchill , Manatsha Boga Thura 
Published: September 2023

AbstractIn this paper, we argue that archaeology plays a significant role in promoting history, and the two disciplines complement each other. The study uses archaeological monuments and sites to assess how these can be used to effectively enhance the transmission of history to the public. This paper demonstrates the tremendous value of historical archaeology beyond colonial records as a source of data for the voiceless. Our study concludes that well‐researched and packaged historical and archaeological information is essential to the promotion of the heritage tourism industry as part of the knowledge‐based economy.
Comparing intralesional triamcinolone and verapamil‐triamcinolone injections in keloids: A single‐blinded randomised clinical trial
Authors: Haghani‐Dogahe Zahra , Hadadi Ramin , Esmailzadeh Mojdeh , Mobayen Mohammadreza 
Published: September 2023

AbstractIntroductionIn this clinical trial, we investigated the efficacy of two treatment methods for keloids resulting from surgical incisions: intralesional triamcinolone injections alone versus in combination with verapamil.Material and MethodsPatients were divided into two groups: one received triamcinolone alone (Group T) and the other received a triamcinolone‐verapamil blend (Group VT). Regular treatments were conducted until the keloids were nearly flat or for a maximum of eight sessions.ResultsBoth groups showed significant improvements, but Group VT saw quicker resolution of skin redness and needed fewer sessions. Though the Vancouver Scar Scale (VSS) scores were generally similar across both groups, Group VT exhibited greater improvements, leading to lower final scores. The VT group also attained normal scar flexibility faster than the T group.ConclusionThese findings suggest that the combination of verapamil and triamcinolone provides a more effective treatment for keloids, thereby highlighting the potential of verapamil in scar reduction.
Serine deficiency exacerbates psoriatic skin inflammation by regulating S‐adenosyl methionine‐dependentDNAmethylation andNF‐κBsignalling activation in keratinocytes
Authors: Meng Qinqin , Liu Ying , Yao Leiqing , Ma Zhimiao , Guo Lu , Hu Ting , Luo Yixin , Chen Jiaoling , Dang Erle , Li Zhengxiao 
Published: September 2023

AbstractBackgroundSerine metabolism is crucial for tumour oncogenesis and immune responses. S‐adenosyl methionine (SAM), a methyl donor, is typically derived from serine‐driven one‐carbon metabolism. However, the involvement of serine metabolism in psoriatic skin inflammation remains unclear.ObjectivesTo investigate the association between serine metabolism and psoriatic skin inflammation.MethodsClinical samples were collected from patients with psoriasis and the expression of serine biosynthesis enzymes was evaluated. The HaCaT human keratinocyte cell line was transfected with small interfering RNA (siRNA) of key enzyme or treated with inhibitors. RNA sequencing and DNA methylation assays were performed to elucidate the mechanisms underlying serine metabolism‐regulated psoriatic keratinocyte inflammation. An imiquimod (IMQ)‐induced psoriasis mouse model was established to determine the effect of the SAM administration on psoriatic skin inflammation.ResultsThe expression of serine synthesis pathway enzymes, including the first rate‐limiting enzyme in serine biosynthesis, phosphoglycerate dehydrogenase (PHGDH), was downregulated in the epidermal lesions of patients with psoriasis compared with that in healthy controls. Suppressing PHGDH in keratinocytes promoted the production of proinflammatory cytokines and enrichment of psoriatic‐related signalling pathways, including the tumour necrosis factor‐alpha (TNF‐α) signalling pathway, interleukin (IL)‐17 signalling pathway and NF‐κB signalling pathway. In particular, PHGDH inhibition markedly promoted the secretion of IL‐6 in keratinocytes with or without IL‐17A, IL‐22, IL‐1α, oncostatin M and TNF‐α (mix) stimulation. Mechanistically, PHGDH inhibition upregulated the expression of IL‐6 by inhibiting SAM‐dependent DNA methylation at the promoter and increasing the binding of myocyte enhancer factor 2A. Furthermore, PHGDH inhibition increased the secretion of IL‐6 by increasing the activation of NF‐κB via SAM inhibition. SAM treatment effectively alleviated IMQ‐induced psoriasis‐like skin inflammation in mice.ConclusionsOur study revealed the crucial role of PHGDH in antagonising psoriatic skin inflammation and indicated that targeting serine metabolism may represent a novel therapeutic strategy for treating psoriasis.
Flexural strength and translucency of barium‐silicate‐filled resin nanoceramics for additive manufacturing
Authors: Park Geun‐Taek , Ko Kyung‐Ho , Huh Yoon‐Hyuk , Park Chan‐Jin , Cho Lee‐Ra 
Published: September 2023

AbstractObjectiveThis in vitro study aimed to evaluate the flexural strength (FS) and translucency parameter (TP) of resin nanoceramics (RNCs) with barium silicate for additive manufacturing.Materials and MethodsAn RNC slurry was prepared by mixing a barium silicate filler and resin monomer. For the FS tests, specimens with three filler contents (0, 50, and 63 wt%) were designed according to ISO6872 for dental ceramics and ISO10477 for dental polymers. These specimens were then formed into discs with thicknesses of 1 and 2 mm for TP measurement.ResultsIn the specimens prepared according to ISO6872, the FS increased significantly depending on the filler content. However, in the case of ISO10477, there was no significant difference between the FSs of the specimens with 0 and 50 wt% filler contents. The increase in thickness affected translucency, and the lowest translucency was obtained at a filler content of 63 wt%. The filler distribution was dense in the specimen with 63 wt% filler and uniform but relatively sparse in the specimen with 50 wt% filler. More voids were observed in the specimen with 63 wt% filler. The thickness and filler content of the specimen affected its TP. The TP of the specimen with 63 wt% filler was similar to that of human enamel.ConclusionThe FS was significantly higher at a filler content of 63 wt%. The lowest translucency was obtained at a filler content of 63 wt% for all tested thicknesses.Clinical SignificanceIncreasing the filler content was advantageous for the mechanical properties of the RNCs. A high filler content led to low translucency in the RNCs. Therefore, the esthetics of human teeth can be reproduced if layering according to the filler content is performed in areas where esthetic characteristics are required.
Antipsychotic use among older patients with dementia receiving home health care services: Prevalence, predictors, and outcomes
Authors: Wang Jinjiao , Shen Jenny Y. , Conwell Yeates , Yu Fang , Nathan Kobi , Heffner Kathi L. , Li Yue , Caprio Thomas V. 
Published: September 2023

AbstractBackgroundAntipsychotic use is a safety concern among older patients in home health care (HHC), particularly for those with Alzheimer's disease and related dementias (ADRD). The objective of this study was to examine the prevalence and predictors of antipsychotic use among older adults with and without ADRD who received HHC, and the association of antipsychotic use with outcomes among patients living with ADRD.MethodsIn this secondary analysis of adults ≥65 years receiving care from an HHC agency in New York in 2019 (N = 6684), we used data from the Outcome and Assessment Information Set, Medicare HHC claims, and home medication review results in the electronic HHC records during a 60‐day HHC episode. ADRD was identified by diagnostic codes. Functional outcome was the change in the composite activities of daily living (ADL) score from HHC admission to HHC discharge (measured in 5833 patients), where a positive score means improvement and a negative score means decline. Data were analyzed using logistic (predictors) and linear regression (association with outcome) analyses.ResultsThe point prevalence of antipsychotic use was 17.2% and 6.6% among patients with and without ADRD, respectively. Among patients living with ADRD, predictors of antipsychotic use included having greater ADL limitations (odds ratio [OR] = 1.30, p = 0.01), taking more medications (OR = 1.04, p = 0.02), having behavioral and psychological symptoms (OR = 5.26, p = 0.002), and living alone (OR = 0.52, p = 0.06). Among patients living with ADRD, antipsychotic use was associated with having less ADL improvement at HHC discharge (β = −0.70, p < 0.001).ConclusionsHHC patients living with ADRD were more likely to use antipsychotics and to experience worse functional outcomes when using antipsychotics. Antipsychotics should be systematically reviewed and, if contraindicated or unnecessary, deprescribed. Efforts are needed to improve HHC patients' access to nonpharmacological interventions and to provide education for caregivers regarding behavioral approaches to manage symptoms in ADRD.
Rethinking Control and Trust Dynamics in and between Organizations
Authors: Lumineau Fabrice , Long Chris , Sitkin Sim B. , Argyres Nicholas , Markman Gideon 
Published: September 2023

AbstractControl and trust issues are at the heart of collaboration in and between organizations. In this introduction to the Special Issue (SI) on the control‐trust dynamics, we first propose an integrative framework to take stock of the main themes discussed in both the micro and macro literature. We then contextualize how the papers in this issue flesh out key mechanisms underlying the interplay between control and trust over time. The remainder of the introduction highlights directions for future research by refining and extending our understanding of control and trust as mechanisms of collaboration across levels of analysis. Our future research suggestions are organized around the main building blocks of control‐trust research: (1) constructs, (2) interactions, (3) actors, (4) temporal dynamics, (5) outcomes, and (6) context.
Supporting School Staff: Insights From Employee Health and Well‐Being Programs
Authors: Pitt Barnes Seraphine , Lang Jason E. 
Published: September 2023

ABSTRACTBackgroundThe workplace is an important setting for health protection, health promotion, and disease prevention programs. In the school setting, employee health and well‐being programs can address many physical and emotional concerns of school staff. This systematic review summarizes evidence‐based approaches from employee health and well‐being interventions supporting nutrition and physical activity (PA) in a variety of workplace settings.MethodsThe 2‐phase systematic review included a search for articles within systematic reviews that met our criteria (addressing employee health and well‐being programs; published 2010‐2018; Phase 1) and the identification of individual articles from additional searches (addressing school‐based employee interventions; published 2010‐2020; Phase 2). We included 35 articles.FindingsAcross all studies and types of interventions and workplace settings, findings were mixed; however, multicomponent interventions appeared to improve health behaviors and health outcomes among employees.Implications for School Health Policy, Practice, and EquitySchools can apply this evidence from employee health and well‐being programs in various workplace settings to implement coordinated and comprehensive employee health and well‐being programs.ConclusionsEmployee health and well‐being programs may be effective at supporting nutrition and PA. Schools can use findings from employee health and well‐being programs in workplaces other than schools to support school staff.
International trade: Smarten up to talk the talk
Authors: Haas Levi , Schenk‐Hoppé Klaus R. 
Published: September 2023

AbstractInternational trade is currently under fire from many sides. Protectionist trade policies are on the rise, putting an end to the decade‐long March of free trade. Making sense of the daily headlines and having an informed opinion on your own has rarely been more important than it is now. Our work aims to explain the driving forces behind international trade, its history, how it shaped the world, its economic models, issues ranging from job losses to the environment and why buying local often makes no sense. We summarize the most important academic literature on these topics in a non‐technical, educational manner. If the reader feels enabled to form their own views on the pros and cons of international trade and that they can ‘talk the talk’, our effort has been fruitful.
Establishing an optimal working relationship with patients with an antisocial personality disorder. Aspects and processes in the therapeutic alliance
Authors: Aerts J. E. M. , Rijckmans M. J. N. , Bogaerts S. , van Dam A. 
Published: September 2023

AbstractObjectiveDeveloping good interpersonal relationships is one of the main impediments for people with an antisocial personality disorder (ASPD). However, in treatment of psychiatric disorders, establishing a strong therapeutic alliance (TA) is important for effective treatment. Nevertheless, there is little knowledge on how to establish this TA with this challenging patient group. This study investigates which factors are important in TA development.MethodFor this study, a qualitative research methodology is applied. In‐depth interviews with therapists experienced in treating ASPD were conducted and analysed through thematic analysis.ResultsThe analysis revealed six themes important in alliance formation: the patient's needs, regulating interpersonal dynamics, connective attitude, connective skills, treatment process and treatment goals. Each theme is defined including aspects of the recommended therapeutic attitude and required skills for therapists working with patients with ASPD.ConclusionsThis study determined that, for therapists working with patients with ASPD, several key factors are essential in establishing a strong TA. These factors include the ability to be firm, authentic, non‐judgmental and genuinely involved. An attentive presence is crucial, in which the therapist takes initiative in establishing contact and makes the patient feel that he is truly seen as an autonomous and equal person. In doing so, the therapist needs to provide clarity and structure while remaining perceptive to boundary violations. The therapist must be able to set limits using a clear yet kind tone of voice. Furthermore, it was notable that an intensive appeal is made to the therapist's reflective capacity in these treatments.
Home transfusions are implemented using diverse approaches in Japan
Authors: Tanaka Asashi , Fujita Hiroshi , Ohashi Kota , Tsujikawa Akihito , Uchiyama Kanami , Ito Tatsuya , Kawashima Koichiro , Kodama Reiko , Mine Takashi , Okuda Makoto , Endoh Teruo , Fukuyoshi Youko , Kitazawa Junichi , Sueoka Eisaburo , Nagai Kazuhiro , Ishida Akaru , Matsuzaki Koji , Kato Yoko , Takanashi Kazuo , Takahashi Koki 
Published: September 2023

AbstractBackground and ObjectivesJapan's ageing society has increased the need for home healthcare, including home transfusions. We hence aimed to elucidate the purpose and utilization of home transfusions in Japan, which has not been clarified to date.Materials and MethodsClinics throughout Japan that provide home care and have experience in performing blood transfusions were surveyed. The study period was February to December 2019, and information of patients receiving home red blood cell transfusions, including patient background, pre‐transfusion laboratory data and the purpose of the transfusions, was collected.ResultsHaematological malignancies and solid tumours accounted for 70% of the patients' underlying diseases, with the former being significantly more common in urban areas. Regarding the purpose of the home transfusions, haematologists focused on symptom improvement, whereas gastroenterology surgeons focused on life support. Furthermore, maintenance of life was more likely to be the aim in the group of patients with the lowest level of activities of daily living. The main items that were significantly associated with a low haemoglobin level before transfusion included age ≥90 years and a gastroenterologist being the physician in charge.ConclusionHome transfusions were found to be performed in a restrictive and diverse manner in Japan. Life support is the second most common purpose of home transfusion in Japan, and optimizing effective home transfusion remains a challenge.
On the motivic Segal conjecture
Authors: Gregersen Thomas , Rognes John 
Published: September 2023

AbstractWe establish motivic versions of the theorems of Lin and Gunawardena, thereby confirming the motivic Segal conjecture for the algebraic group of th roots of unity, where is any prime. To achieve this we develop motivic Singer constructions associated to the symmetric group and to , and introduce a delayed limit Adams spectral sequence.