bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between Sleep Disordered Breathing and Neonatal Outcomes in Nulliparous Individuals
Authors: Delgado Arlin , Kendle Anthony M. , Randis Tara , Donda Keyur , Salemi Jason L. , Facco Francesca L. , Parker Corette B. , Reddy Uma M. , Silver Robert M. , Basner Robert C. , Chung Judith H. , Schubert Frank P. , Pien Grace W. , Redline Susan , Parry Samuel , Grobman William A. , Zee Phyllis C. , Louis Judette M. 
Published: June 2023

Objective Our objective was to determine whether objectively measured sleep-disordered breathing (SDB) during pregnancy is associated with an increased risk of adverse neonatal outcomes in a cohort of nulliparous individuals.
Study Design Secondary analysis of the nuMom2b sleep disordered breathing substudy was performed. Individuals underwent in-home sleep studies for SDB assessment in early (6–15 weeks' gestation) and mid-pregnancy (22–31 weeks' gestation). SDB was defined as an apnea-hypopnea index ≥5 events/h at either time point. The primary outcome was a composite outcome of respiratory distress syndrome, transient tachypnea of the newborn, or receipt of respiratory support, treated hyperbilirubinemia or hypoglycemia, large-for-gestational age, seizures treated with medications or confirmed by electroencephalography, confirmed sepsis, or neonatal death. Individuals were categorized into (1) early pregnancy SDB (6–15 weeks' gestation), (2) new onset mid-pregnancy SDB (22–31 weeks' gestation), and (3) no SDB. Log-binomial regression was used to calculate adjusted risk ratios (RR) and 95% confidence intervals (CIs) representing the association.
Results Among 2,106 participants, 3% (n = 75) had early pregnancy SDB and 5.7% (n = 119) developed new-onset mid-pregnancy SDB. The incidence of the primary outcome was higher in the offspring of individuals with early (29.3%) and new onset mid-pregnancy SDB (30.3%) compared with individuals with no SDB (17.8%). After adjustment for maternal age, chronic hypertension, pregestational diabetes, and body mass index, new onset mid-pregnancy SDB conferred increased risk (RR = 1.43, 95% CI: 1.05, 1.94), where there was no longer statistically significant association between early pregnancy SDB and the primary outcome.
Conclusion New onset, mid-pregnancy SDB is independently associated with neonatal morbidity.
Key Points
Palladium-Loading Ceramic Catalytic Membrane Reactors for Mizoroki–Heck Reaction
Authors: Wu Xiaojin , Chen Rizhi , Zhang Fei , Zhou Yong , Wang Shuangqiang , Zhao Yao 
Published: June 2023

AbstractThe general and efficient palladium-loading ceramic catalytic membrane reactor has been first reported to apply in the Mizoroki–Heck reaction. The as-fabricated catalytic membrane Pd-KH792-CM has shown high activity and selectivity in the flow-through Mizoroki–Heck reactions. The consistently high activity of the catalytic membrane in the five cycles has also proved its good stability and recyclability. Synthesis of drug molecules has further demonstrated that the catalytic membrane protocol is a powerful and comprehensive alternative to the traditional Mizoroki–Heck cross-coupling.
Endoscopic ultrasound-guided gastroenterostomy with lumen-apposing metal stents: a retrospective multicentric comparison of wireless and over-the-wire techniques
Authors: Monino Laurent , Perez-Cuadrado-Robles Enrique , Gonzalez Jean-Michel , Snauwaert Christophe , Alric Hadrien , Gasmi Mohamed , Ouazzani Sohaib , Benosman Hedi , Deprez Pierre H. , Rahmi Gabriel , Cellier Christophe , Moreels Tom G. , Barthet Marc 
Published: June 2023

Background Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) using lumen-apposing metal stents (LAMSs) appears to be effective and safe in gastric outlet obstruction (GOO); however, the EUS-GE procedure is not standardized, with the use of assisted or direct methods still debated. The aim of this study was to compare the outcomes of EUS-GE techniques focusing on an assisted with orointestinal drain wireless endoscopic simplified technique (WEST) and the nonassisted direct technique over a guidewire (DTOG).
Method This was a multicenter European retrospective study involving four tertiary centers. Consecutive patients who underwent EUS-GE for GOO between August 2017 and May 2022 were included. The primary aim was to compare the technical success and adverse event (AE) rates of the different EUS-GE techniques. Clinical success was also analyzed.
Results 71 patients (mean [SD] age 66.2 10 years; 42.3 % men; 80.3 % malignant etiology) were included. Technical success was higher in the WEST group (95.1 % vs. 73.3 %; estimate of relative risk from odds ratio (eRR) 3.2, 95 %CI 0.94–10.9; P = 0.01). The rate of AEs was lower in the WEST group (14.6 % vs. 46.7 %; eRR 2.3, 95 %CI 1.2–4.5; P = 0.007). Clinical success was comparable between the two groups at 1 month (97.5 % vs. 89.3 %). The median follow-up was 5 months (range 1–57).
Conclusion The WEST resulted in a higher technical success rate with fewer AEs, with clinical success comparable with the DTOG. Therefore, the WEST (with an orointestinal drain) should be preferred when performing EUS-GE.
Electrochemically Controlled Ruthenium-Catalyzed Olefin ­Metathesis
Authors: Rovis Tomislav , Nguyen Jennifer A. , Cabanero David C. 
Published: June 2023

AbstractThe development of a system to electrochemically control ruthenium-catalyzed olefin metathesis is reported. Catalyzed by a commercially-available bis-NHC Ru complex, this system displays a broad substrate scope with very short reaction times, as well as excellent levels of temporal control over metathesis with only electricity as a stimulus.
Pregabalin and gabapentin for chronic low back pain without radiculopathy: a systematic review
Authors: Tatit Rafael Trindade , Poetscher Arthur Werner , Oliveira Carlos Augusto Cardim de 
Published: June 2023

Abstract
Background Chronic low back pain (CLBP) is a global health problem, and gabapentin and pregabalin are often used in the treatment of patients without associated radiculopathy or neuropathy. Therefore, determining their efficacy and safety is of enormous value.
Objective To examine the efficacy and safety of using gabapentin and pregabalin for CLBP without radiculopathy or neuropathy.
Methods We performed a search on the CENTRAL, MEDLINE, EMBASE, LILACS, and Web of Science data bases for clinical trials, cohorts, and case-control studies that evaluated patients with CLBP without radiculopathy or neuropathy for at least eight weeks. The data were extracted and inserted into a previously-prepared Microsoft Excel spreadsheet; the outcomes were evaluated using the Cochrane RoB 2 tool, and the quality of evidence, using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.
Results Of the 2,230 articles identified, only 5 were included, totaling 242 participants. In them, pregabalin was slightly less efficacious than amitriptyline, the combination of tramadol/acetaminophen, and celecoxib, and pregabalin added to celecoxib showed no benefit when compared to celecoxib alone (very low evidence for all). On the other hand, although one study with gabapentin did not support its use in a general sample of patients with low back pain, another found a reduction in the pain scale and improved mobility (moderate evidence). No serious adverse events were observed in any of the studies.
Conclusion Quality information to support the use of pregabalin or gabapentin in the treatment of CLBP without radiculopathy or neuropathy is lacking, although results may suggest gabapentin as a viable option. More data is needed to fill this current gap in knowledge.
AQP4-IgG NMOSD, MOGAD, and double-seronegative NMOSD: is it possible to depict the antibody subtype using magnetic resonance imaging?
Authors: Fragoso Diego Cardoso , Salles Luana Michelli Oliveira de Paula , Pereira Samira Luisa Apóstolos , Callegaro Dagoberto , Sato Douglas Kazutoshi , Rimkus Carolina de Medeiros 
Published: June 2023

Abstract
Background There is clinical and radiological overlap among demyelinating diseases. However, their pathophysiological mechanisms are different and carry distinct prognoses and treatment demands.
Objective To investigate magnetic resonance imaging (MRI) features of patients with myelin-oligodendrocyte glycoprotein associated disease (MOGAD), antibody against aquaporin-4(AQP-4)-immunoglobulin G-positive neuromyelitis optica spectrum disorder (AQP4-IgG NMOSD), and double-seronegative patients.
Methods A cross-sectional retrospective study was performed to analyze the topography and morphology of central nervous system (CNS) lesions. Two neuroradiologists consensually analyzed the brain, orbit, and spinal cord images.
Results In total, 68 patients were enrolled in the study (25 with AQP4-IgG-positive NMOSD, 28 with MOGAD, and 15 double-seronegative patients). There were differences in clinical presentation among the groups. The MOGAD group had less brain involvement (39.2%) than the NMOSD group (p = 0.002), mostly in the subcortical/juxtacortical, the midbrain, the middle cerebellar peduncle, and the cerebellum. Double-seronegative patients had more brain involvement (80%) with larger and tumefactive lesion morphology. In addition, double-seronegative patients showed the longest optic neuritis (p = 0.006), which was more prevalent in the intracranial optic nerve compartment. AQP4-IgG-positive NMOSD optic neuritis had a predominant optic-chiasm location, and brain lesions mainly affected hypothalamic regions and the postrema area (MOGAD versus AQP4-IgG-positive NMOSD, p= 0 .013). Furthermore, this group had more spinal cord lesions (78.3%), and bright spotty lesions were a paramount finding to differentiate it from MOGAD (p = 0.003).
Conclusion The pooled analysis of lesion topography, morphology, and signal intensity provides critical information to help clinicians form a timely differential diagnosis.
Study of polymerization of high-pressure nitrogen by ab initio molecular dynamics
Authors: Melicherová Dominika , Martoňák Roman 
Published: June 2023

We study properties of nitrogen at high pressure and temperature (100–120 GPa, 2000–3000 K) where molecular and polymeric phases compete both in solid and liquid phase. We employ ab initio MD simulations with the SCAN functional and study the pressure-induced polymerization in liquid nitrogen for system sizes up to 288 atoms in order to reduce finite-size effects. The transition is studied upon both compression and decompression, and at 3000 K, it is found to take place between 110 and 115 GPa, coming close to experimental data. We also simulate the molecular crystalline phase close to the melting line and analyze its structure. We show that the molecular crystal in this regime is highly disordered, in particular, due to pronounced orientational and also translational disorder of the molecules. Its short-range order and vibrational density of states are very close to those of the molecular liquid revealing that the system likely represents a plastic crystal with high entropy.
What are health professionals’ perceptions of conducting routine growth assessments and lifestyle interventions? A qualitative study involving allied health professionals, nurses and doctors in rural and regional New South Wales
Authors: Schwartzkoff Emma , Burrows Tracy , Bailey Andrew , Sneddon Eloise , Duncanson Kerith 
Published: June 2023

Background Allied health professionals, nurses and doctors within the New South Wales (NSW) public health system provide trusted health information to a large proportion of families across the state. This means they are well positioned to opportunistically assess and discuss child weight status with families. Prior to 2016, weight status was not routinely addressed in most NSW public health settings, however recent policy changes promote quarterly growth assessments for all children aged under 16 years who attend these facilities. The Ministry of Health recommend health professionals use the 5 As framework, a consultation approach to encourage behaviour change, to identify and manage children with overweight or obesity. This study aimed to explore allied health professionals’, nurses’ and doctors’ perceptions of conducting routine growth assessments and providing lifestyle support to families in a local health district in rural and regional NSW, Australia. Methods This descriptive, qualitative study involved online focus groups and semi-structured interviews with health professionals. Audio recordings were transcribed and coded for thematic analysis, with rounds of data consolidation between research team members. Results Allied health professionals, nurses and doctors who work in a variety of settings within a local health district of NSW participated in one of four focus groups (n = 18 participants) or semi-structured interviews (n = 4). The predominant themes related to: (1) health professionals’ professional identity and their perceived scope of practice; (2) interpersonal qualities of health professionals; (3) the service delivery ecosystem in which health professionals worked. Diversity in attitudes and beliefs about routine growth assessments were not necessarily specific to discipline or setting. Conclusions Allied health professionals, nurses and doctors recognise the complexities involved in conducting routine growth assessments and providing lifestyle support to families. The 5 As framework used in NSW public health facilities to encourage behaviour change may not allow clinicians to address these complexities in a patient centred way. The findings of this research will be used to inform future strategies aimed at embedding preventive health discussions into routine clinical practice, and to support health professionals to identify and manage children with overweight or obesity.
Bone health, body composition and physical fitness dose–response effects of 16 weeks of recreational team handball for inactive middle‐to‐older‐aged males – A randomised controlled trial
Authors: Carneiro Ivone , Krustrup Peter , Castagna Carlo , Pereira Rita , Jørgensen Niklas Rye , Coelho Eduardo , Póvoas Susana 
Published: June 2023

ABSTRACTIn this study we aimed at analysing the effects of different weekly exercise volumes (1, 2 or 3 times 60‐min) on bone health, body composition and physical fitness of inactive middle‐to‐older‐aged males, after 16 weeks of recreational team handball (RTH). Fifty‐four men (68 ± 4 years, stature 169 ± 6 cm; body mass 78.4 ± 10.7 kg; fat mass 27.1 ± 5.3%; BMI 27.4 ± 2.9 kg/m2; VO2peak 27.3 ± 4.8 mL/min/kg) were randomised into three intervention groups (TH1, n = 13; TH2, n = 15; or TH3, n = 12, performing 1, 2 and 3 weekly 60‐min training sessions, respectively), and a control group (CG, n = 14). The training sessions consisted mainly of RTH matches played as small‐sided and formal game formats (4v4, 5v5, 6v6 or 7v7) with adapted rules. Matches’ mean and peak heart rate (HR) ranged from 78–80% and 86–89%HRmax, respectively, and distance covered from 4676 to 5202 m. A time x group interaction was observed for procollagen type‐1 amino‐terminal propeptide (P1NP), osteocalcin (OC), carboxy‐terminal type‐1 collagen crosslinks (CTX), sclerostin, upper and lower body dynamic strength, right arm fat mass, left and right arm, right leg and android total mass (TM; p ≤ 0.047) with the greatest effects being shown for TH2 and TH3 groups. Post‐intervention group differences were observed in CTX, left arm and right leg TM (TH3 > TH1), P1NP (TH2 > CG), OC, right arm TM (TH3 > CG), upper (CG < TH1, TH2 and TH3) and lower body dynamic strength (CG < TH1 and TH3) (p ≤ 0.047). RTH was effective in enhancing bone health, body composition and physical fitness in middle‐to‐older‐aged males, especially for the intervention groups that performed 2–3 weekly training sessions.ClinicalTrials.gov ID: NCT05295511.Trial registration: ClinicalTrials.gov identifier: NCT05295511.Highlights

After 16 weeks of recreational team handball small‐sided and formal matches, inactive middle‐to‐older‐aged males improved bone health, body composition and physical fitness, by performing 1, 2 or 3 60‐min weekly sessions, however, greater improvements were shown in the groups that performed 2 or 3 weekly training sessions.
Training intensity was similar across the intervention groups that performed recreational team handball for 1, 2 or 3 60‐min weekly sessions, which means that training volume is most likely to be the reason for the different health effects shown.
The very high fun levels reported by all intervention groups shows that recreational team handball is a social and fun exercise modality for middle‐to‐older‐aged males, with potential to intrinsically motivate the participants and assure long‐term adherence to exercise.
Falling off a balcony: a student experiment
Authors: Cross Rod 
Published: June 2023

Abstract
Falling accidents are very common and are sometimes fatal. A fatal fall could be accidental, suicidal or homicide and needs to be investigated. A simple model of falls from a balcony is presented, together with simulated experimental results obtained using a straight rod falling over a horizontal rail. The experiments involve basic mechanics and would be suitable in a student laboratory or as a lecture demonstration.
A flexible and highly sensitive capacitive pressure sensor with fast response based on a hierarchically micro-structured PDMS dielectric layer
Authors: Li Jiamin , Zhang Jie , Qin Lei , Lv Luyu , Liu Tianxiang , Zhang Yanting , Dhakal Rajendra , Li Xiao , Liu Tian , Li Yuanyue , Yao Zhao 
Published: June 2023

Abstract
Flexible high-sensitivity pressure sensors have seen rapid growth in the last few years in applications like electronic skin, smart wearables and medical health monitoring. In this work, we develop a high-flexibility capacitive pressure sensor design based on a hierarchical, micro-pyramid-structured dielectric layer of polydimethanes. The goal of this design is to achieve low-hysteresis capacitive pressure sensors with increased sensitivity and reduced response time. To optimize the performance of the proposed pressure sensor, we designed and fabricated several different micro-pyramid structures on the silicon template using standard photolithography and anisotropic etching. As a result, the pressure sensor with a hierarchical micro-pyramid structure achieved through graphic transfer has the best performance, with a sensitivity of up to 2.64 kPa−1 (0–2 kPa), a response time of 45 ms, a low limit of detection of < 8 Pa, and high stability over at least 1200 loading cycles. As a result of these remarkable performance features, the pressure sensor proposed can be effectively utilized for the detection of physiological signals as well as mechanical pressure which can be widely used in the fields of motion sensing, health monitoring and intelligent robots.
Buried interfacial gate oxide for tri-gate negative-capacitance fin field-effect transistors: approach and investigation
Authors: Chauhan Vibhuti , Samajdar Dip Prakash 
Published: June 2023

Abstract
Negative-capacitance fin field-effect transistors (NC-FinFETs), due to their superior gate electrostatics and dominance over short channel effects (SCEs), have been a key technology among conventional devices. The improved device performance in terms of the various engineering practices has paved the way for the advancement of NC-FinFETs. In the following work, we have proposed a novel buried oxide strategy for the NC-FinFET architecture, in which we have altered the depth of the interfacial gate oxide (IGO) layer inside the channel and analyzed the performance characteristics using TCAD Sentaurus. First, we varied the IGO thickness that was buried inside the channel and performed a comparative analysis between the DC, mixed-mode, and SCE parameters for the various buried configurations of the proposed NC-FinFET in order to realize the optimized depth. We also present the tolerable degradation in the circuit characteristics that occurs with the varying buried IGO (BIGO) depth. It can be inferred from the presented interface trap discussion that the idea of BIGO thickness holds well for low-power electronics.
Knowledge features enhanced intelligent fault detection with progressive adaptive sparse attention learning for high-power diesel engine
Authors: Li He , Liu Fengchun , Kong Xiangxin , Zhang Jinjie , Jiang Zhinong , Mao Zhiwei 
Published: June 2023

Abstract
High-power diesel engines are core power equipment in some key fields, and fault diagnosis is of great significance for improving their long-term operational reliability and safety. The lack of sufficient fault samples, known as few-shot conditions, has resulted in the performance degradation of most current intelligent diagnostic methods under complex and variable working conditions. Moreover, the end-to-end deep learning diagnostic models based on implicit layer features do not have clear physical meanings, making it difficult for intelligent diagnostic models to be recognized by equipment managers in key fields. Mechanism-based fusion methods can effectively alleviate the above problems by incorporating fault-sensitive features with clear physical meanings. However, the lack of sufficient knowledge-related features that can characterize fault information is a challenge facing current mechanism fusion methods. In this work, we propose a progressive adaptive sparse attention mechanism-guided knowledge feature incremental mining method. Fault-sensitive segments are obtained based on attention-supervised learning with an improved activation function. Both knowledge-related features and hidden layer features from these segments are incorporated into the feature library. A differential constraint is designed between the distribution of knowledge features and hidden layer features, encouraging the model to focus on learning new knowledge-related features in the subsequent iteration process. Finally, a feature set containing a large amount of knowledge features is constructed to enhance fault diagnosis. Testing on a V12 diesel engine test bench under the conditions of rich and few-shot data sets, shows that the proposed method significantly enhances the fault recognition performance of diesel engines under complex variable working conditions and few-shot data set conditions.