bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isolation and Characterization of Antibacterial Compounds from Ganoderma boninense Against Methicillin-Resistant Staphylococcus aureus (MRSA)
Authors: Abdullah Syahriel , Yee Soon Ling , Daim Sylvia Jerome , Khim Phin Chong 
Published: February 2023

Background: Community and nosocomial-associated methicillin-resistant Staphylococcus aureus (MRSA) infections in Malaysian healthcare setting are terrifically increasing in recent years. There is an urgent need for an effective antibacterial agent to cope with this important issue. Due to the development of new antibiotics is not parallel with the increase of cases of infections, researchers have initiated isolation of compounds from natural resources to develop new potent therapeutic agent. Meanwhile, Ganoderma boninense is an oil palm devastating pathogen, which has been known to contain many bioactive compounds that might be potential to be developed as a new source of therapeutic agent.
Keywords: Ganoderma boninense, MRSA, Ergosterol, Ganoboninketal, antibacterial, dereplication
Effects of pH on Phosphorus Recovery from Different Composition of Food Waste Using Anaerobic Batch Digestion
Authors: Selaman R. , Wid Newati 
Published: February 2023

Background: Anaerobic digestion is a process by which microorganisms break down biodegradable material in the absence of oxygen. The process involves hydrolysis, acidogenesis and methanogenesis stages. Anaerobic digestion of food waste has been widely investigated for biogas recovery but limited study was performed on phosphorus recovery, which is reported depleting. Food waste is produced every day and dumped on landfill for final disposal which may lead to environmental issues such as odour problems and greenhouse gases release, due to decomposing of food waste, hence impacts global climate change. In anaerobic digestion pH is a very crucial parameter in an attempt to recover phosphorus as it highly influences the production of organic acids during acidogenesis.
Keywords: anaerobic batch digestion, food waste, palm oil mill effluent, phosphorus recovery
The Trainee to Surgeon Continuum
Authors: Mohd Yusof Ibrahim  
Published: February 2023

This special issues is dedicated to the 22nd Sabah State Surgical Clinical Conference which was conducted on the 11- 14 March 2020, held at Queen Elizabeth Hospital, Kota Kinabalu Sabah, Malaysia. The theme of this conference was “The Trainee to Surgeon Continuum: Connecting the Dots”. Although the main aim of this conference is dedicated to surgical trainees and medical officers aspiring a career in surgery, conference for the surgical paramedics were also run concurrently. This is a commendable approach as by having a strong, dedicated and fully trained surgical teams are obviously essential in all areas of surgical department.
Teamwork is essential in surgery. A surgeon alone cannot adequately fulfill his daily tasks, neither in the operating theater nor on the surgical ward. Good teamwork is linked to improved patient outcomes, better medical staff satisfaction and a reduced incidence of burnouts. Good teamwork is linked to improve patient outcomes due to lesser adverse events, good coordination and cost saving. Improvement of teamwork ability in operating theaters leads to reduced technical errors and lower perioperative mortality.
This conference has created a history of its own as this is the first conference conducted with “new-normal” during the COVID19 era with strict Standard Operation Procedure (SOP) in-placed during the whole proceeding of the conference. The organizer has invited many prominent national and local prominent speakers and academics in the field of surgery to share their wealth of knowledge and experience with the participants. Many activities and programs were available in this conference including “hands on training”, poster and paper presentation. The conference had attracted more than 200 local and national participants. More than 30 papers were presented as oral and poster presentations. In this special issues only 10 papers have been selected to be published.
Special briefing on General Surgical Training in Malaysia, Masters, MedEX, MRCS, JSCFE FRCS and NSR by the President of the College of Surgeons, Academy of Medicine of Malaysia (CSAMM Council).
Surgery is a major medical specialty that uses manual techniques to treat a pathological condition in patients. It is a long and difficult journey to become a surgeon, fraught with much stress and many sacrifices and thus is becoming less popular choice for this generation of junior doctors. The conference will definitely be able to stimulate more interest in Surgery.
ĐÁNH GIÁ KẾT QUẢ SỐNG THÊM SAU ĐIỀU TRỊ UNG THƯ DẠ DÀY BẰNG HÓA CHẤT TRƯỚC PHẪU THUẬT CẮT DẠ DÀY VÉT HẠCH D2 TẠI KHOA ĐIỀU TRỊ THEO YÊU CẦU BỆNH VIỆN K
Authors: Chử Quốc Hoàn , Nguyễn Thị Hà , Dương Chí Thành 
Published: February 2023

Mục tiêu: Đánh giá kết quả sống thêm và tỉ lệ tai biến, biến chứng của phẫu thuật cắt dạ dày vét hạch D2 đối với ung thư dạ dày giai đoạn tiến triển tại chỗ, tại vùng được điều trị hóa chất tiền phẫu. Đối tượng: bệnh nhân được chẩn đoán ung thư biểu mô dạ dày giai đoạn lan rộng tại chỗ tại vùng được hóa chất trước phẫu thuật cắt dạ dày vét hạch D2 tại khoa Điều trị theo yêu cầu Bệnh viện K. Kết quả: Đặc điểm nhóm nghiên cứu: Tuổi trung bình 58,1 ± 9,1 tuổi, tỉ lệ nam/nữ là 1,8. Vị trí u hang môn vị chiếm 69,0%, thân vị chiếm 16,7%, tâm phình vị chiếm 14,3%. Tỉ lệ T3 chiếm 11,9%, T4 chiếm 88,1%. Tỉ lệ di căn hạch chiếm 66,7%. Đại thể u: thể loét chiếm 59,5%, thể sùi 4,8%, thể loét thâm nhiễm hoặc thâm nhiễm 35,7%. Mô bệnh học: thể kém biệt hóa hoặc tế bào nhẫn chiếm tỉ lệ cao nhất với 42,9%, thể biệt hóa vừa chiếm 38,1%, thể biệt hóa cao chiếm 19,0%. Kết quả điều trị: Đánh giá đáp ứng sau 4 đợt hóa trị trước phẫu thuật dựa trên các phương tiện chẩn đoán hình ảnh đạt 61,9%, dựa trên đánh giá tổn thương trong mổ đạt 83,3%. Không có bệnh nhân nào đạt được đáp ứng hoàn toàn trên lâm sàng, tỉ lệ đáp ứng hoàn toàn trên mô bệnh học là 4,8%. Không có bệnh nhân nào tiến triển phải chuyển phác đồ điều trị, tuy nhiên đánh giá trong mổ có 16,7% bệnh nhân không đáp ứng. Tỉ lệ tai biến biến chứng chung tương đối thấp, không có bệnh nhân tử vong hoặc mổ lại trong 30 ngày đầu, không có trường hợp nào xuất hiện các biến chứng chảy máu sau mổ, rò bục miệng nối sau mổ, tắc ruột sau mổ, hẹp miệng nối. Không phát hiện trường hợp nào xuất hiện suy gan, thận sau mổ. Gặp 2 trường hợp xuất hiện viêm phổi sau mổ chiếm 4,8% và 2 trường hợp nhiễm trùng vết mổ. Thời gian theo dõi trung bình là 28,6 tháng. Tỉ lệ sống thêm không bệnh tính đến thời điểm kết thúc nghiên cứu là 50% và sống thêm toàn bộ là 66,7%.
NGHIÊN CỨU ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ XỬ TRÍ XUẤT HUYẾT TIÊU HÓA DO GIÃN TĨNH MẠCH DẠ DÀY TẠI BỆNH VIỆN BẠCH MAI
Authors: Nguyễn Hữu Việt Anh , Nguyễn Anh Tuấn 
Published: February 2023

Mục tiêu: Nhận xét đặc điểm lâm sàng, cận lâm sàng của xuất huyết tiêu hóa giãn tĩnh mạch dạ dày và nhận xét kết quả xử trí cấp cứu xuất huyết tiêu hóa vỡ giãn tĩnh mạch dạ dày tại Bệnh viện Bạch Mai. Đối tượng và phương pháp nghiên cứu: mô tả tiến cứu bệnh nhân xuất huyết tiêu hóa do vỡ giãn tĩnh mạch dạ dày điều trị tại bệnh viện Bạch Mai từ tháng 7/2021 tới tháng 8/2022. Kết quả: 101 bệnh nhân, nam giới chiếm 96%, độ tuổi trung bình 55,03±11,98 tuổi. Mức độ xơ gan Child - pugh A 14,9%, Child - pugh B chiếm 48,5%, Child - pugh C chiếm 36,6%. Mức độ mất máu nhẹ chiếm 12,9%, mức độ vừa chiếm 64,4%, nặng chiếm 22,8%. Kiểm soát được nguồn chảy máu thành công chiếm 95,1%, bệnh nhân ra viện chiếm: 73,3%, nặng xin về chiếm 16,8%, chuyển tuyến chiếm: 9,9%. Có 80 bệnh nhân truyền hồng cầu khối, 20 bệnh nhân truyền tiểu cầu và 31 bệnh nhân truyền huyết tương tươi. Kết luận: chẩn đoán sớm và can thiệp sớm nguồn chảy máu và điều trị các biến chứng khác của xơ gan như là hội chứng não gan, gan thận. Phối hợp đa chuyên khoa điều trị mang lại hiệu quả cao trong điều trị xuất huyết tiêu hóa do vỡ giãn tinh mạch dạ dày.
PENANAMAN NILAI – NILAI PENDIDIKAN KARAKTER DI SD NEGERI 2 KECAPI
Authors: SUDARMAJI BAMBANG 
Published: February 2023

Pendidikan karakter adalah suatu proses penerapan nilai-nlai moral dan agama pada peserta didik melalui ilmu-ilmu pengetahuan, penerapan nilai-nilai tersebut baik terhadap diri sendiri, keluarga, sesama teman, terhadap pendidik dan lingkungan sekitar maupun terhadap Tuhan Yang Maha Esa. Perkembangan sosial anak usia sekolah dasar sudah bertambah, dari yang awalnya hanya bersosial dengan keluaga di rumah, kemudian berangsur-angsur mengenal orang-orang disekitarnya. Anak pada usia ini juga telah mengenal gaya hidup digital, baik itu dari rumah, teman-teman, sekolah dan lingkungan sekitar. Era digital tidak hanya punya dampak positif, tapi juga berdampak negatif, disinilah peran kita sebagai orang tua, pendidik dan masyarakat dewasa membimbing dan mengawasi anak untuk menjalaninya dengan baik, tepat, dan bermanfaat positif bagi anak itu sendiri.
Optimization of weather forecasting for cloud cover over the European domain using the meteorological component of the Ensemble for Stochastic Integration of Atmospheric Simulations version 1.0
Authors: Lu Yen-Sen , Good Garrett H. , Elbern Hendrik 
Published: February 2023

Abstract. We present the largest sensitivity study to date for cloud cover using the Weather Forecasting and Research model (WRF V3.7.1) on the European domain. The experiments utilize the meteorological part of a large-ensemble framework, ESIAS-met (Ensemble for Stochastic Integration of Atmospheric Simulations). This work demonstrates the capability and performance of ESIAS for large-ensemble simulations and sensitivity analysis. The study takes an iterative approach by first comparing over 1000 combinations of microphysics, cumulus parameterization, planetary boundary layer (PBL) physics, surface layer physics, radiation scheme, and land surface models on six test cases. We then perform more detailed studies on the long-term and 32-member ensemble forecasting performance of select combinations. The results are compared to CM SAF (Climate Monitoring Satellite Application Facility) satellite images from EUMETSAT (European Organisation for the Exploitation of Meteorological Satellites). The results indicate a high sensitivity of clouds to the chosen physics configuration. The combination of Goddard, WRF single moments 6 (WSM6), or CAM5.1 microphysics with MYNN3 (Mellor–Yamada Nakanishi Niino level 3) or ACM2 (Asymmetrical Convective Model version 2) PBL performed best for simulating cloud cover in Europe. For ensemble-based probabilistic simulations, the combinations of WSM6 and SBU–YLin (Stony Brook University Y. Lin) microphysics with MYNN2 and MYNN3 performed best.
Digital transformation and knowledge management in IT processes in the public service
Authors: Caldeira Alexandre Rodrigues , Tolentino Renata de Sousa da Silva 
Published: February 2023

The constant transformations in a globalized world promote technological advancement and allow the interconnection of sectors. Thus, the gradual growth of data flow in institutions has consumed network resources, requiring modern technologies for storage. Thus, it is necessary to analyze knowledge management policies in the exchange of information, especially in the public sector. The technique adopted was a case study and as data collection instruments, a questionnaire was applied and an interview was carried out with the managers and employees of the technology area of ​​the Subsecretariat of Technology of the Municipality of Contagem. The research resulted in the elaboration of an interactive and innovative tool for the control of one of the services of the Information Technology sector, as well as the need to create a knowledge transmission policy
Causal Impotence and Complicity
Authors: Galvin Richard , Harris John R. 
Published: February 2023

Abstract
Moral problems such as climate change and global poverty result from widespread human action, and hence, are unaffected by changes in any individual's behavior—for instance, the harms of climate change will obtain whether I drive my car or not. This problem of causal impotence seems potentially devastating for consequentialists, but more easily addressed by deontologists. The deontologist can argue that (e.g.) even if our acts will have no effect on climate change, our using fossil fuels makes us complicit in, and hence, blameworthy for, these wrongs. We argue that, despite initial appearances, appeals to complicity do not extricate deontologists from this problem. When our actions do not make a difference, we cannot be held responsible for being complicit in wrongs such as climate change and global poverty. As a result, we conclude that the problem of causal impotence is as vexing for deontologists as it is for consequentialists.
Feminism, Honor and Self-Defense: A Response to Hereth
Authors: Statman Daniel 
Published: February 2023

AbstractSometimes victims cannot defend themselves against the threat posed to them, but they can nevertheless harm or even kill their aggressors. Since they cannot defend themselves, it is unclear how such harming can be justified under the title of self-defense. According to the “Honor Solution,” by violently resisting their aggressors, victims do (partially) defend themselves because they protect their honor. Blake Hereth recently argued that this solution is incompatible with the feminist commitment that sexual assault victims ought not to be shamed or dishonored. The purpose of my paper is to reject Hereth's criticism and defend the Honor Solution.
Alkaline Phosphatase is an Independent Risk Factor for Periprosthetic Fractures in Total Joint Arthroplasty
Authors: Lung Brandon E. , Kim Matthew , McLellan Maddison , Callan Kylie , Wang Edward D. , McMaster William , Yang Steven , So David H. 
Published: February 2023

Background:
Serum alkaline phosphatase (ALP) is a biomarker for chronic low-grade inflammation along with hepatobiliary and bone disorders. High abnormal ALP levels in blood have been associated with metabolic bone disease and high bone turnover.

Methods:
All primary total hip and knee arthroplasties from 2005 to 2019 were queried from the National Surgical Quality Improvement Program database. Patients with available serum ALP levels were included and stratified to low (<44 IU/L), normal (44 to 147 IU/L), and high (>147 IU/L). A risk-adjusted multivariate logistic regression was used to analyze ALP as an independent risk factor of complications.

Results:
The analysis included 324,592 patients, consisting of 11,427 low ALP, 305,977 normal ALP, and 7,188 high preoperative ALP level patients undergoing total joint arthroplasty. Adjusted multivariate logistic regression analysis showed high ALP level patients had an overall increased risk of readmission within 30 days of surgery compared with the control group (odds ratio [OR], 1.69; P < 0.01). High ALP patients also had an increased risk of postoperative periprosthetic fracture (OR, 1.6), postoperative wound infection (OR, 1.81), pneumonia (OR, 2.24), renal insufficiency (OR, 2.39), cerebrovascular disease (OR, 2.2), postoperative bleeding requiring transfusion (OR, 1.83), sepsis (OR, 2.35), length of stay > 2 days (OR, 1.47), Clostridium difficile infection (OR, 2.07), and discharge to a rehab facility (OR, 1.41) (all P < 0.05). A low ALP level was also associated with increased postoperative bleeding transfusion risk (OR, 1.12; P < 0.01) and developing a deep vein thrombosis (OR, 1.25; P = 0.03).

Conclusion:
Abnormal serum ALP levels in patients undergoing primary total joint arthroplasty are associated with increased postoperative periprosthetic fracture risk and medical complications requiring increased length of stay and discharge to a rehabilitation facility.
World Health Organization International Strategy Facing the Covid-19 Pandemic For Stronger and Recovery G.20: Competition and Globalization
Authors: Endang Susilowati  , Erwin Susanto  
Published: February 2023

The International Market generates potential new opportunities. Another traditional motive for companies to become multinationals is to secure the resources needed. With a multidomestic strategy, state managers have autonomy to tailor the company's products as necessary to meet the specific needs and preferences of local customers. The company uses a global strategy to offer standard products across country markets, with a competitive strategy defined by headquarters. A transnational strategy is an international strategy that companies use to achieve global efficiency and local responsiveness. The Covid-19 pandemic has had a broad impact on daily life, especially in terms of socio-economics. Various efforts were made by WHO and collaborated with various countries to overcome this pandemic and make policies and handling to deal with the virus. This paper explores WHO's international strategy during the Covid-19 pandemic for the speed of handling Covid-19 in the global context.
Postawy uczniów wobec kultury fizycznej, lekcji wychowania fizycznego i ćwiczeń
Authors: Gądek Adrian 
Published: February 2023

Wstęp: Pojęcie postawy wobec kultury fizycznej składa się z wielu określeń o węższym znaczeniu. Bardziej sprecyzowane znaczenie dotyczy wszelakich jej elementów. Można wyróżnić postawę wobec własnego ciała, jego budowy, higieny, sprawności fizycznej, różnych form wypoczynku i aktywności itp. Celem badań było określenie postaw wobec kultury fizycznej, lekcji wychowania fizycznego i ćwiczeń młodzieży kończącej szkoły ponadpodstawowe.Materiał i metody: Badaniami objęto tarnowskich uczniów, którzy uczęszczali do ostatnich klas liceów ogólnokształcących, techników i szkół branżowych pierwszego stopnia. Badaniami zostało objętych 751 uczniów, w tym 413 (55,0%) mężczyzn i 338 (45,0%) kobiet. W przeprowadzonych badaniach podstawową metodą był sondaż diagnostyczny. W celu uzyskania niezbędnych danych, które posłużyły do zweryfikowania postawionych hipotez zastosowano technikę ankietowania, z następującym narzędziem badawczym: Kwestionariusz do badania postaw młodzieży wobec kultury fizycznej autorstwa S. Strzyżewskiego.Wyniki: Jak wykazały przeprowadzone badania, każdy ze wskaźników postaw uczniów wobec kultury fizycznej był na średnim poziomie, a ich wartości wahały się od 2,06 do 2,55 pkt. Średnia wartość wskaźnika globalnego postawy wyniosła 2,28 pkt. Najwyższy wynik dotyczył komponentu poznawczego (2,55), a najniższą średnią wartość odnotowano w przypadku komponentu behawioralnego (2,06). W komponencie behawioralnym wystąpiło największe zróżnicowanie danych. Mężczyźni cechowali się wyższymi przeciętnymi wartościami badanych wskaźników postaw niż kobiety.Wnioski: Z otrzymanych danych wynika, że postawy wobec kultury fizycznej badanej młodzieży kształtują się na zadowalającym, choć średnim poziomie. Badani mężczyźni wykazywali wyższe wartości w poszczególnych komponentach postawy jak i wskaźniku globalnym. Uczniowie z techników dominowali nad pozostałymi typami szkół.
Pengaturan Metode Omnibus Dalam Undang-Undang Nomor 13 Tahun 2022 Tentang Pembentukan Peraturan Perundang-Undangan
Authors: Dhezya Pandu Satresna  
Published: February 2023

Permasalahan over regulasi yang berakhir saling tumpang tindihnya Undang-Undang adalah cikal bakal kenapa Undang-Undang No. 13 tahun 2022 ini lahir. Yang salah satunya dalam undang-undang ini mengenalkan metode omnibus, yang kita tahu menjadi trauma masyarakat Indonesia terkhususnya buruh karena adanya UU Cipta Kerja yang fenomenal. Dari situ penulis ingin mencari tahu bagaimana pengaturan dan sistem hukum yang disuguhkan dalam Undang-Undang No.13 tahun 2022 serta bagaimana penerapan metode omnibus di negara lain. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian hukum yuridis normatif. Dari penelitian ini dapat disimpulkan bahwa masih terdapat kekurangan dalam substansi hukum metode omnibus dalam Undang-Undang No 13 tahun 2022 untuk mengatur keterkaitan materi muatan. Serta perlunya pemerintah melihat penerapan negara lain dalam metode omnibus contohnya Turki, yang menurut penulis memiliki solusi dalam mencegah deadlock dalam proses pembahasan legislasi undang-undang dengan metode omnibus.
MenPas 1.0: plataforma online de evaluación psicosocial
Authors: Sánchez-García Carolina , Pérez-Romero Nuria , Quiñones-Rodríguez Yarisel , Gónzalez-Ruiz Sergio L. , Pastrana-Brincones José L. , Enríquez-Molina Rocío , García Rabaneda José Antonio , Sánchez Izquierdo María , Reigal Garrido Rafael E. , Morales-Sánchez Verónica , Hernández-Mendo Antonio 
Published: February 2023

El uso de instrumentos informatizados y en línea se ha incrementado notablemente en las últimas décadas. Sucesos como la COVID-19 han influido en la consolidación de su uso, siendo herramientas de trabajo muy útiles para evaluación e investigación. El objetivo del presente trabajo fue analizar una plataforma de evaluación online denominada MenPas 1.0, explorando sus áreas de trabajo y el flujo de datos de los últimos años. Se ha seguido una estrategia descriptiva para analizar las posibilidades que ofrece la plataforma, así como el tráfico de datos que posee y número de usuarios. Los resultados muestran que esta plataforma ofrece herramientas vinculadas a las siguientes áreas: ansiedad, atención, autoconcepto, autorregistros, burnout, búsqueda de talentos, calidad de vida, dinámica grupal, entrenamiento mental, inteligencia emocional, estrés, generalizabilidad, hipnosis, liderazgo, motivación, observación, organizaciones/calidad, socialización, toma de decisiones o visualización. Actualmente, tiene más de 16 mil usuarios registrados y acumula más de un millón trescientos mil sucesos. Algunos de los cuestionarios alojados han sido respondidos más de 60.000 veces. Además, sus usuarios proceden de múltiples países europeos y asiáticos, americanos o de Oceanía. Los resultados ponen de relieve el amplio espectro de uso que tiene la plataforma, las posibilidades de almacenamiento y procesamiento de datos que permite y la universalización de los recursos informatizados.
Development of an online gamma radiation measurement system
Authors: Jiang YunRui , Lai WanChang , Lin HongJian , Wu PeiLian 
Published: February 2023

Raw coal is often interspersed with rocks as well as soil fragments, so natural γ-radiation measurement is used for online detection of coal quality in the coal mining and processing production process. To solve the problems of system development, data acquisition and transmission and online calibration in online γ radiation measurement, an online γ radiation measurement system was developed based on ATMEGA8L microcontroller. The upper computer software developed with Qt realizes the functions of RS485 serial communication between the upper computer and the lower computer, online configuration of the instrument working mode, real-time display and recording of the measurement results, and recording and query of the working log. After testing, the software of the upper computer is easy to operate, friendly human-computer interaction, and can realize the required functions to meet the current requirements for the intelligence of production instruments, and the RSD of the measurement results of the system is 1.1% for long time operation, with good stability.