bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two Unnarrated Stories in Horace's Roman Odes (Carm.3.2.1–12 and 3.6.21–32): Echoes of Vergil's UnfinishedAeneidand a Lowlife Epigram
Authors: Werner Shirley 
Published: July 2023

AbstractWithin the rhetorical frameworks of exhortation and illustrative exemplum, Horace's second and sixth Roman Odes offer compressed, contrasting images of a young person's education and transformation, presenting these as stories about apuerand avirgo, respectively, in a lyric mode that does not narrate. In the first of these stories (Carm. 3.2.1–12), Horace slyly usurps characters from Vergil's unfinishedAeneid, alluding to some of its distinctive narrative techniques, but also draws on the similes and plot structure of its Iliadic model. The second of Horace's stories (Carm. 3.6.21–32) plays off his first, as he converts theadulta virgowho figures inCarm. 3.2 into her antitype. This story has as its intertext an obscene Hellenistic epigram by Automedon. Horace makes both intertextual and metatextual use of his models, while his indirect references, through Homer, to Vergil's intended design for his emergingAeneidmay be considered under the new heading of extratextual.
Prototyping an additive co-fabrication workflow for architecture: utilizing cyanobacterial MICP in robotic deposition
Authors: Armaly Perla , Iliassafov Lubov , Kirzner Shay , Kashi Yechezkel , Barath Shany 
Published: July 2023

Abstract
With the increasing need for architectural sustainability, biodesign offers a new approach to incorporating living organisms in building materials. Bacteria hold a range of biological activities that impact their environment, and which could enable the solidification of inorganic materials; this has already been seen with microbially-induced carbonate precipitation that strengthens bonds between sand particles. This paper describes the novel development of an additive co-fabrication manufacturing process, demonstrating an interdisciplinary approach of architecture and microbiology. Specifically, the activity of a biological deposition (i.e., cyanobacterial calcium carbonate precipitation) and its integration with that of a robotic deposition (i.e., a sand-based biomixture) within an architectural biofabrication workflow. Two bacterial strains were successfully grown in potential sand-based construction materials. Microbiological protocols, such as optical density and fluorescence measurements, were then applied to identify parameters, for harvesting light through photosynthesis and harnessing it to the sedimentation of calcium carbonate. Assessments of the proposed mechanical delivery system and printing properties enabled the outlining of a suitable robotic deposition system for sand-based mixtures. Through examinations of these microbiological and mechanical protocols, this paper outlines design strategies and tradeoffs for an integrated workflow, that corresponds with both the biological (micro) and architectural (macro) scales.
The impact of L2 English on choice perception, interpretation, and preference for L1 Arabic speakers
Authors: AboHamed Lama , Mashaqba Bassil , Al-Khawaldeh Nisreen 
Published: July 2023

AbstractThis article compares risk tolerance of native Arabic speakers under two language contexts: their first language (L1 Arabic) and their foreign language (L2 English). We aim to evaluate whether thinking in a foreign language actually reduces the negative effects of cognitive biases, such as loss aversion and mental accounting, on financial decision-making. Toward this aim, we conducted two experiments in which the risk tolerance levels of 144 participants were evaluated across four different types of decision-making problems: the Asian disease problem, the financial crisis problem, the discount problem, and the ticket/money lost problem. In study 1, we adopted Keysar et al.’s (2012,Psychological Science,23, 661–668) experiment to test the effect of L2 on framing effects associated with loss aversion, and in Study 2, we adopted Costa et al.’s (2014,Cognition,130, 236–254) experiment to test the effect of L2 on framing effects associated with mental accounting biases. We found that individuals were risk-averse for gains and risk-seeking for losses when presented with choices in their L1, but were almost unaffected by framing manipulation under the L2 condition. When it came to mental accounting, however, framing effects were nearly absent in both L1 and L2 conditions. In our investigation, we examined various potential factors that could explain the foreign language effect on decision-making. The primary factor that appears to account for this linguistic phenomenon is the heightened cognitive and emotional distance experienced when using an L2.
Intergenerational Transmission of BMI and Educational Outcomes in Children and Adolescents
Authors: Alrouh Hekmat , van Bergen Elsje , Dolan Conor , Boomsma Dorret I. 
Published: July 2023

AbstractIndividual differences in educational attainment (EA) and physical health, as indexed by body mass index (BMI), are correlated within individuals and across generations. The aim of our study was to assess the transmission of these traits from parents to their offspring in childhood and adolescence. We analyzed BMI and EA in 13,916 families from the Netherlands. Data were available for 27,577 parents (mean age 33) and 26,855 of their offspring at 4 and 12 years of age. We employed structural equation modeling to simultaneously estimate the phenotypic transmission of BMI and EA from parents to offspring, the spousal correlations, and the residual child BMI-EA associations after accounting for intergenerational transmission and testing for gender differences therein. We found a significant intergenerational transmission of BMI to BMI in childhood (age 4; standardized regression coefficient β = .10) and adolescence (age 12; β = .20), and of EA to academic achievement in adolescence (β = .19). Cross-trait parent-to-offspring transmission was weak. All transmission effects were independent of parent or offspring gender. We observed within-person EA-BMI correlations that were negative in parents (∼−.09), positive in children (∼.05) and negative in adolescents (∼−.06). Residual EA-BMI were positive in children (∼.05) and insignificant in adolescents. Spousal correlations were .46 for EA, .21 for BMI, and ∼−.09 cross-trait. After accounting for spousal correlations, the intergenerational transmission for BMI and EA is mainly predictive within, but not across, traits. The within-person correlation between BMI and EA can change in direction between childhood and adulthood.
Comprehensive evaluation of artifact reduction and tissue recovery effects of metal artifact reduction technique based on full-reference metric
Authors: Jung Yunsub , Song You Seon , Lee In Sook , Rhee Seung Joon 
Published: July 2023

AbstractFor the comprehensive evaluation of metal artifact reduction (MAR) technique, not only the removal of metal artifacts but also the evaluation of the area restored by MAR is required. We propose a method to comprehensively evaluate the effect by MAR in this study. We have conducted the computed tomography scan to acquire both the evaluation image and the reference image for the full-reference based evaluation. The evaluation image and reference image were reconstructed into 24 image sets according to the tube potentials, image reconstruction method, and use of the MAR technique. Images of two different positions were selected according to the distance from metal and material (bone, tissue) distribution, and bone and tissue were automatically segmented in both evaluation and reference images. The values of full width at half the maximum (FWHM) and centroid were extracted after Gaussian modeling of each segmented region. Then, we computed four evaluation metrics (FWHMNM: non-MAR to non-metal ratio of FWHM, FWHMM: MAR to non-metal ratio of FWHM, CENTNM: non-MAR to non-metal ratio of centroid, CENTM: MAR to non-metal ratio of centroid), and the MAR image and non-MAR image were compared. The overlap ratio automatically segmented from the evaluation image and reference image were position 1 (bone: 99.61%, tissue: 99.23%) with 80 kVp, position 1 (bone: 99.32%, tissue: 99.56%) with 120 kVp, position 2 (bone: 99.20%, tissue: 99.73%) with 80 kVp, and position 2 (bone: 99.23%, tissue: 99.67%) with 120 kVp. The FWHMNMshowing the change of image pixel value by metal artifact was calculated as (bone: 1.32–1.46, tissue: 1.08–1.16) at 80 kVp and (bone: 1.19–1.27, tissue: 1.02–1.05) at 120 kVp. More metal artifacts occurred at 80 kVp tube potential. Regardless of the tube potential and image reconstruction method, the MAR showed an overall artifact reduction effect (1 < FWHMM < FWHMNM). However, distortion of pixel values occurred due to the MAR in regions where metal artifacts were high in proximity to metal (1 < FWHMNM < FWHMM). Overall, the average value of the medium was maintained (CENTM: 0.98–1.03) after MAR application, but there was a change of image value in region around the metal (CENTM: 0.97–1.11). In this study, we propose a new method to evaluate the effect of metal artifacts and MAR technique using full-reference based method. Metal artifacts, effect of MAR technique, and side-effect caused by MAR technique were quantitatively analyzed through proposed method. There are some limitations in applying it to clinical imaging since our method is a reference-based evaluation. However, our experimental results were important for understanding the effects of the MAR technique and its functional properties.
Efficient practical method for differential protection of power transformer in the presence of the fault current limiters
Authors: Sahebi Ali , Askarian‐Abyaneh Hossein , Sadeghi Seyed Hossein Hesamedin , Samet Haidar , Malik Om Parkash 
Published: July 2023

AbstractThe algorithms of the present generation of practical differential relays are based on two methods. The first method is based on the ratio of the harmonic content of the differential current, and the second one is based on the length of the time interval between the zero‐crossing points of the differential current, called the gap‐detection method. However, these methods suffer from the installation of the fault current limiters (FCLs) in the power system and current transformer (CT) saturation phenomenon. This paper deals with a simple practical method for differential relays to secure their performance. In the suggested method, a classifying algorithm is used to categorize the input signal of the relay and then the best method of the present generation of differential relays is employed. By this simple decision, the method takes the advantage of harmonic‐based and gap‐detection methods, while avoiding their drawbacks. To prove the robustness of the suggested method, a test bench with a resistive solid‐state fault current limiter (SSFCL) is implemented and examined in different situations. The results validate the consistency and the accuracy of the modified technique not only in the absence and the presence of the FCL but in the case of CT saturation.
Knowledge‐based multiple hypothesis tracking and identification of manoeuvring reentry targets
Authors: Lee Chan‐Seok , Whang Ick‐Ho , Ra Won‐Sang 
Published: July 2023

AbstractThis paper addresses the integrated tracking and identification problem of a manoeuvring reentry target that performs intentional lateral manoeuvres to disrupt ground radars. Unlike previous approaches, prior knowledge of the lift‐induced drag is incorporated into a new manoeuvring model to describe the reentry target dynamics more explicitly. This model can account for the constraint between lift and drag, which is beneficial in ensuring the reliability of target state estimation. Noticing that the lift‐induced drag is an inherent characteristics of a reentry target that distinguishes the target's identity from others belonging to the same class, the integrated target tracking and identification problem is formulated within the framework of the multiple hypothesis testing about a set of manoeuvring models constructed by different prior knowledge. The proposed approach enables the authors to derive the optimal solution to the given problem in a mathematically rigorous manner. To cope with the real‐time implementation issue, a hypothesis merging strategy is also devised in view of maintaining the target identification performance. Simulation results demonstrate that the proposed scheme provides superior performance and reliability both in target tracking and identification compared to the existing method, despite imperfectness of prior knowledge.
Comparison between tubeless mini-percutaneous nephrolithotomy versus flexible ureterorenoscopic lithotripsy for the treatment of upper ureteral calculi larger than 1 cm
Authors: Chou Chu-Min , Wang Chung-Jing , Jou Yeong-Chin , Cheng Ming-Chin , Shen Cheng-Huang , Lin Chang-Te 
Published: July 2023

Abstract

Background
This study aimed to assess the outcome and safety of tubeless mini-percutaneous nephrolithotomy (mPCNL) and flexible ureterorenoscopic lithotripsy (fURSL) in treating upper ureteral stones larger than 1 cm.

Materials and Methods
Between July 2017 and June 2020, 218 patients who underwent tubeless mPCNL and fURSL for upper ureteral calculi larger than 1 cm were enrolled in this study. Patient characteristics and perioperative outcomes and complications were evaluated by retrospective chart review.

Results
Immediate stone-free rates after the procedure were 100% of patients for the tubeless mPCNL and 71.0% of patients for the fURSL group (P = 0.004). The mean ± SD operative time per patient was 79.8 ± 21.8 minutes in the tubeless mPCNL group, and it was 99.7 ± 33.8 minutes in the fURSL groups (P = 0.009). The average hospital stay was 2.7 ± 1.9 days in the tubeless mPCNL group and 1.5 ± 1.2 days in the fURSL group (P < 0.001). The rates of febrile episode for the tubeless mPCNL and fURSL groups were 14.3% and 2.3%, respectively (P = 0.028)

Conclusions
Tubeless mPCNL and fURSL are safe and feasible treatment options for proximal ureteral calculi larger than 1 cm. Tubeless mPCNL offers better outcome of higher stone-free rate and shorter operation time compared with fURSL but with a higher rate of febrile complications and longer hospital stay.
One-year follow-up of a multifocal intraocular lens with optimized elevated phase shift
Authors: Fernández Joaquín , Srinivasan Sathish , Burguera Noemí , Martínez Javier , Rodríguez-Vallejo Manuel 
Published: July 2023

Purpose:
To evaluate the standard outcomes of a multifocal intraocular lens (mIOL) with optimized elevated phase shift (EPS).

Setting:
Qvision, Ophthalmology Department, VITHAS Almería, Spain.

Design:
Retrospective observational.

Methods:
41 patients, consecutively operated on cataracts or refractive lens exchange with the implantation of the Liberty 640PM (EPS 2.0) and followed during 12 months, were included in the analysis. Retrieved variables were visual acuities at far, intermediate, and near distances; defocus curves (VADC); and prediction error of 4 formulas optimized for IOLMaster 500 and Pentacam AXL Wave. Patient-reported outcomes were also obtained for assessing spectacle independence, satisfaction, bothersome to dysphotopsia, difficulties in daily life tasks, and decision to be operated with the same mIOL.

Results:
The median monocular efficacy with best distance correction was 0, 0.1, and 0.1 logMAR at far, intermediate, and near distances, respectively, with patients achieving binocularly a median of 0 logMAR at the 3 distances. VADC showed a depth of field of 3 diopters (D) above 0.2 logMAR with a median increase of 0.07 logMAR from −1.5 to −2.5 D. Complete spectacle independence was achieved at far distance, whereas 97.6% and 85.4% was achieved at intermediate and near distances, respectively. 7.3% of patients were bothered by dysphotopsia, and 92.6% of patients were likely to be operated again.

Conclusions:
EPS 2.0 restored patients' vision in the full range of the depth of field with a nearly monotone decrease of visual performance from far to near, achieving high rates of spectacle independence at all distances and with low positive dysphotopsia rates (ClinicalTrials.gov Identifier: NCT05735990).
Live Imaging of the Dehydration Effect of Isosorbide on the Normal and Hydropic Guinea Pig Cochleae Using Optical Coherence Tomography
Authors: Kakigi Akinobu , Egami Naoya , Fujita Takeshi , Uehara Natsumi , Yokoi Jun , Koda Kento , Nibu Ken-ichi , Yamashita Shinji , Yamasoba Tatsuya 
Published: July 2023

Objective
To investigate the isosorbide-induced dehydration effect on the endolymphatic space by intratympanic administration of isosorbide.

Background
Isosorbide, an osmotic diuretic, is used orally as a typical conservative therapy for Menière's disease (MD) in Japan. The dehydration effect occurs 6 hours after isosorbide ingestion. Intratympanic administration of isosorbide resolves endolymphatic hydrops faster than oral ingestion. In addition, the dehydration effect has never been shown directly. Therefore, we investigated the dehydration effect of intratympanic administration of isosorbide on endolymphatic hydrops using optical coherence tomography.

Methods
We used eight Hartley guinea pigs, divided into normal and hydrops groups. In the hydrops group, the animals underwent endolymphatic sac obliteration to create endolymphatic hydrops. We obtained midmodiolar section images of the cochleae using optical coherence tomography. Then, 50 to 70% isosorbide was sequentially administered intratympanically for 5 minutes, and the apical turn of the cochlea was observed. The relative midmodiolar cross-sectional area of the scala media was calculated for quantitative assessment of the endolymphatic space.

Results
In the normal group, 50% isosorbide had a slight but significant dehydration effect on the scala media; at 55 to 70%, Reissner's membrane became flat. In the hydrops group, 50% isosorbide slightly reduced endolymphatic hydrops; 65% flattened Reissner's membrane, and 70% slightly concaved it toward the basilar membrane.

Conclusion
The results suggest that we could select the concentration of isosorbide according to the stage or severity of MD and relief from acute attack. Intratympanic administration of isosorbide may be a promising treatment for patients with MD.
Immediate CPAP Use after Skull Base Reconstruction with Hydroxyapatite Bone Cement
Authors: Cumpston Evan C. , Sualeh Ali H. , Totten Douglas J. , Nelson Rick F. 
Published: July 2023

Objective
The timing for resuming continuous positive airway pressure (CPAP) postoperatively after skull base surgery remains controversial because of the risk of pneumocephalus. We determined the safety of immediate CPAP use after middle cranial fossa (MCF) spontaneous cerebrospinal fluid (sCSF) leak repair with bone cement.

Study Design
Prospective cohort study.

Setting
Tertiary academic medical center.

Patients
Thirteen consecutive patients with CPAP-treated obstructive sleep apnea and temporal bone sCSF leaks who underwent skull base repair with hydroxyapatite bone cement between July 2021 and October 2022.

Interventions
CPAP use resumed on postoperative day 1 after the confirmation of skull base reconstruction with temporal bone computed tomography (CT).

Main Outcome Measures
Postoperative skull base defects on CT, pneumocephalus, or intracranial complications.

Results
The average age was 55.5 ± 8.8 years (±standard deviation), and 69.2% were female with a BMI of 45.39 ± 15.1 kg/m2. Multiple tegmen defects were identified intraoperatively in 53.9% of patients with an average of 1.85 ± 0.99 defects and an average defect size on preoperative imaging of 6.57 ± 3.45 mm. All patients had an encephalocele identified intraoperatively. No residual skull base defects were observed on CT imaging on postoperative day 1. No postoperative complications occurred. One patient developed a contralateral sCSF leak 2 months after repair. There were no recurrent sCSF leaks 1 month postoperatively.

Conclusion
Immediate postoperative CPAP use is safe in patients undergoing MCF sCSF leak repair with bone cement because of the robust skull base repair.
Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth
Authors: Frank Daniel , Bergamasco Maria , Mlodzianoski Michael , Kueh Andrew , Tsui Ellen , Hall Cathrine , Kastrappis Georgios , Voss Anne Kathrin , McLean Catriona , Faux Maree , Rogers Kelly , Tran Bang , Vincan Elizabeth , Komander David , Dewson Grant , Tran Hoanh 
Published: July 2023

AbstractTrabid/ZRANB1missense mutations have been identified in children diagnosed with a range of congenital disorders including reduced brain size, but how Trabid regulates neurodevelopment is not understood. We have characterised these patient mutations in cells and mice to identify a key role for Trabid in the regulation of neurite growth. One of the patient mutations flanked the catalytic cysteine of Trabid and its deubiquitylating (DUB) activity was abrogated. The second variant retained DUB activity, but failed to bind STRIPAK, a large multiprotein assembly implicated in cytoskeleton organisation and neural development.Trabid/ZRANB1knock-in mice harbouring either of these patient mutations exhibited reduced neuronal and glial cell densities in the brain and a motor deficit consistent with fewer dopaminergic neurons and projections. Mechanistically, both DUB-impaired and STRIPAK-binding-deficient Trabid variants impeded the trafficking of adenomatous polyposis coli (APC) to microtubule plus-ends. Consequently, the formation of neuronal growth cones and the trajectory of neurite outgrowth from mutant midbrain progenitors were severely compromised. We propose that STRIPAK recruits Trabid to deubiquitylate APC, and that in cells with mutant Trabid, APC becomes hyperubiquitylated and mislocalised causing impaired organisation of the cytoskeleton that underlie the neuronal and developmental phenotypes.
High-dimensional spectral cytometry panels for whole blood immune phenotyping
Authors: Dott Tom , Culina Slobodan , Chemali Rene , Mansour Cedric Ait , Dubois Florian , Jagla Bernd , Doisne Jean Marc , Rogge Lars , Huetz François , Jönsson Friederike , Commere Pierre-Henri , Santo James Di , Terrier Benjamin , Quintana-Murci Lluis , Duffy Darragh , Hasan Milena ,   Milieu Intérieur Consortium
Published: July 2023

AbstractThe need to understand the mechanisms and pathways of immune responses in pathogenic conditions such as cancer and autoimmunity requires awareness of natural immune variability in healthy subjects. To this end, various systems immunology studies have been established. Among them, theMilieu Intérieur(MI) study was established to define the boundaries of a healthy immune response and identify determinants of immune response variation. MI used immunophenotyping of a 1000 healthy donor cohort by flow cytometry as a principal outcome for immune variance at steady state. For the 10-year longitudinal MI study, we have developed two high-dimensional spectral flow cytometry panels that allow deep characterization of innate and adaptive whole blood immune cells (35 and 34 fluorescent markers, respectively) and standardized the protocol for sample handling, staining, acquisition, and data analysis. This permits the reproducible quantification of over 182 immune cell phenotypes through robust immunophenotyping at a single site. This highly standardized protocol was applied to samples from patients with autoimmune/inflammatory diseases. It is currently used for characterization of the impact of age and environmental factors on peripheral blood immune phenotypes of >400 donors from the initial MI cohort.