bluuebunny/crossref_metadata_2025_split huggingface dataset:
CD30 induces Reed‐Sternberg cell‐like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines
Authors: Watanabe Mariko , Hatsuse Hiromi , Nagao Kazuaki , Nakashima Makoto , Uchimaru Kaoru , Otsu Makoto , Miyazaki Koji , Horie Ryouichi 
Published: June 2023

AbstractClassic Hodgkin lymphoma (cHL) is characterized by multinucleated cells called Reed‐Sternberg (RS) cells and genetic complexity. Although CD30 also characterizes cHL cells, its biological roles are not fully understood. In this report, we examined the link between CD30 and these characteristics of cHL cells. CD30 stimulation increased multinucleated cells resembling RS cells. We found chromatin bridges, a cause of mitotic errors, among the nuclei of multinucleated cells. CD30 stimulation induced DNA double‐strand breaks (DSBs) and chromosomal imbalances. RNA sequencing showed significant changes in the gene expression by CD30 stimulation. We found that CD30 stimulation increased intracellular reactive oxygen species (ROS), which induced DSBs and multinucleated cells with chromatin bridges. The PI3K pathway was responsible for CD30‐mediated generation of multinucleated cells by ROS. These results suggest that CD30 involves generation of RS cell‐like multinucleated cells and chromosomal instability through induction of DSBs by ROS, which subsequently induces chromatin bridges and mitotic error. The results link CD30 not only to the morphological features of cHL cells, but also to the genetic complexity, both of which are characteristic of cHL cells.
Cheating and the effect of promises in Indian and German children
Authors: Kanngiesser Patricia , Sunderarajan Jahnavi , Woike Jan K. 
Published: June 2023

AbstractCheating is harmful to others and society at large. Promises have been shown to increase honesty in children, but their effectiveness has not been compared between different cultural contexts. In a study (2019) with 7‐ to 12‐year‐olds (N = 406, 48% female, middle‐class), voluntary promises reduced cheating in Indian, but not in German children. Children in both contexts cheated, but cheating rates were lower in Germany than in India. In both contexts, cheating decreased with age in the (no‐promise) control condition and was unaffected by age in the promise condition. These findings suggest that there may exist a threshold beyond which cheating cannot be further reduced by promises. This opens new research avenues on how children navigate honesty and promise norms.
Defragmenting Learning
Authors: Kapatsinski Vsevolod 
Published: June 2023

AbstractIn the 1990s, language acquisition researchers and theoretical linguists developed an interest in learning mechanisms, and learning theorists rediscovered the verbal learning tradition. Nonetheless, learning theory and language acquisition continued to develop largely independently, which has stymied progress in both fields. However, exciting progress is happening in applying learning theory to language, and, more recently, in using language learning data to advance domain‐general learning theory. These developments raise hopes for a bidirectional flow of information between the fields. The importance of language data for learning theory and of learning theory for understanding language is briefly discussed.
Tackling the anxiety of learning statistics: The mystery of the red envelope
Authors: Robinson Melanie A. , Soublière Jean‐François , Agogué Marine , Grégoire Denis A. , Rua Tuvana , Plourde Yves 
Published: June 2023

AbstractMost graduate programs in management require students to carry out a substantive research project. However, few management students have a comfortable command of the statistical techniques needed to realize such quantitative projects. This can lead to student anxiety and stress, which challenges instructors to devise ways to build students’ self‐efficacy with statistical analysis. Drawing on game‐based learning principles, we developed an exercise to help students in a graduate‐level research methods course practice these statistical techniques. Designed around a series of four gamified challenges, students perform basic statistical analyses (correlations, t‐tests, and simple linear regression) to solve puzzles and unlock a reward hidden in a mysterious red envelope. We used the exercise on seven occasions (five times in the methods course and twice in a graduate program preparatory course). After launching it in fall 2021, we observed that students were engaged and enthusiastic about the exercise. To ascertain its effectiveness more systematically, we collected data in five subsequent sections using a pretest/posttest design (N = 84) which showed that perceptions of statistics self‐efficacy increased following the exercise. We conclude by suggesting that our exercise can be tailored to other learning contexts such as management and statistics‐centered courses.
The relationship between ascending aortic diameter with left atrial functions and left ventricular mass index in a population with normal left ventricular systolic function
Authors: Ergül Elif , Özyıldız Ali Gökhan , Emlek Nadir , Özyıldız Afag , Durak Hüseyin , Duman Hakan 
Published: June 2023

AbstractAimAscending aortic dilatation is a common clinical issue. In the present study, we aimed to evaluate the relationship between ascending aortic diameter with left ventricular (LV) and left atrial (LA) functions, and LV mass index (LVMI) in a population with normal LV systolic function.MethodsA total of 127 healthy participants with normal LV systolic function took part in the study. Echocardiographic measurements were obtained from each subject.ResultsThe mean age of the participants was 43 ± 14.1 years and 76 (59.8%) were female. The mean aortic diameter of the participants was 32.2 ± 4.7 mm. A negative correlation was found between aortic diameter and LV systolic function (LVEF r = ‐.516, p < .001; Gls r = ‐.370). In addition, there was a strong positive correlation between aortic diameter with LV wall thicknesses, LVMI (r = .745, p < .001), and systolic and diastolic diameters. The relationship between aortic diameter and diastolic parameters was evaluated, a negative correlation with Mitral E, Em, E/A ratio, and a positive correlation with MPI, Mitral A, Am, E/Em ratio were found.ConclusionA strong correlation between ascending aortic diameter with LV and LA functions, and LVMI in individuals with normal LV systolic function.
Climate–ecosystem modelling made easy: The Land Sites Platform
Authors: Keetz Lasse T. , Lieungh Eva , Karimi‐Asli Kaveh , Geange Sonya R. , Gelati Emiliano , Tang Hui , Yilmaz Yeliz A. , Aas Kjetil S. , Althuizen Inge H. J. , Bryn Anders , Falk Stefanie , Fisher Rosie , Fouilloux Anne , Horvath Peter , Indrehus Sunniva , Lee Hanna , Lombardozzi Danica , Parmentier Frans‐Jan W. , Pirk Norbert , Vandvik Vigdis , Vollsnes Ane V. , Skarpaas Olav , Stordal Frode , Tallaksen Lena M. 
Published: June 2023

AbstractDynamic Global Vegetation Models (DGVMs) provide a state‐of‐the‐art process‐based approach to study the complex interplay between vegetation and its physical environment. For example, they help to predict how terrestrial plants interact with climate, soils, disturbance and competition for resources. We argue that there is untapped potential for the use of DGVMs in ecological and ecophysiological research. One fundamental barrier to realize this potential is that many researchers with relevant expertize (ecology, plant physiology, soil science, etc.) lack access to the technical resources or awareness of the research potential of DGVMs. Here we present the Land Sites Platform (LSP): new software that facilitates single‐site simulations with the Functionally Assembled Terrestrial Ecosystem Simulator, an advanced DGVM coupled with the Community Land Model. The LSP includes a Graphical User Interface and an Application Programming Interface, which improve the user experience and lower the technical thresholds for installing these model architectures and setting up model experiments. The software is distributed via version‐controlled containers; researchers and students can run simulations directly on their personal computers or servers, with relatively low hardware requirements, and on different operating systems. Version 1.0 of the LSP supports site‐level simulations. We provide input data for 20 established geo‐ecological observation sites in Norway and workflows to add generic sites from public global datasets. The LSP makes standard model experiments with default data easily achievable (e.g., for educational or introductory purposes) while retaining flexibility for more advanced scientific uses. We further provide tools to visualize the model input and output, including simple examples to relate predictions to local observations. The LSP improves access to land surface and DGVM modelling as a building block of community cyberinfrastructure that may inspire new avenues for mechanistic ecosystem research across disciplines.
Use of novel postharvest Aloe vera gel coating for suppression of ripening changes in Asian pears during long‐term cold storage
Authors: Adhikary Trina , Gill Parmpal Singh , Jawandha Sukhjit Kaur 
Published: June 2023

SummaryThe impact of Aloe vera gel (AVG) coatings (0%, 25%, 50% and 75%) was evaluated on the ripening‐related quality parameters in ‘Patharnakh’ pear fruit during long‐term cold storage (0 ± 1 °C and 90–95% RH). Results showed that AVG coating extended the storage life of fruit by minimising mass loss, decay index, respiration rate, polyphenol oxidase activity, softening enzyme activities like pectin methylesterase (PME) polygalacturonase (PG) and cellulase and maintaining the preliminary sensory quality (SQ), firmness, soluble solid content (SSC), total phenols, titratable acidity (TA) over the control. Among all AVG treatments, 75% AVG treatment was found most promising for suppressing mass long, lowering respiration rate and preserved overall fruit quality up to 60 days of cold storage in ‘Patharnakh’ pear fruit. Hence, AVG proved as an alternative to non‐edible coatings for extending the pear's marketable span and cutting down the adverse effects of health and environmental hazards.
Listeria monocytogenes at the food–human interface: A review of risk factors influencing transmission and consumer exposure in Africa
Authors: Sibanda Thulani , Ntuli Victor , Neetoo Swaleha Hudaa , Habib Ihab , Njage Patrick Murigu Kamau , Parry‐Hanson Kunadu Angela , Andoh Anthonia Helga , Coorey Ranil , Buys Elna M. 
Published: June 2023

SummaryIn African public health systems, Listeria monocytogenes is a pathogen of relatively low priority. Yet, the biggest listeriosis outbreak recorded to date occurred in Africa in 2018. This review highlights the factors that potentially impact L. monocytogenes transmission risks through African food value chains (FVCs). With the high rate of urbanisation, African FVCs have become spatially longer yet still informal. At the same time, dietary diversifications have resulted in increased consumption of processed ready‐to‐eat (RTE) meat, poultry, fishery and dairy products typically associated with a higher risk of L. monocytogenes consumer exposure. With frequent cold chain challenges, the potential of L. monocytogenes growth in contaminated RTE foods can further amplify consumer exposure risks. Moreover, the high prevalence of untreated HIV infections, endemic anaemia, high fertility rate and a gradually increasing proportion of elderly persons expands the fraction of listeriosis‐susceptible groups among African populations. With already warmer tropical conditions, the projected climate change‐induced increases in ambient temperatures are likely to exacerbate listeriosis risks in Africa. As precautionary approaches, African countries should implement systems for the detection and reporting of listeriosis cases and food safety regulations that provide L. monocytogenes standards and limits in high‐risk RTE foods.
Development of simultaneous antioxidant and visual pH‐sensing films based on guar gum loaded with Aronia melanocarpa extract
Authors: Aydogdu Emir Ayca , Yildiz Eda , Oz Emel , Amarowicz Ryszard , Proestos Charalampos , Khan Mohammad Rizwan , Elobeid Tahra , Oz Fatih 
Published: June 2023

SummaryAnthocyanins have attracted increasing attention for different packaging systems due to having functional features such as biocompatibility, antioxidative activity, visible colour response at varying pH values. In this study, the extract of Aronia melanocarpa as anthocyanins source was incorporated into guar gum films to take advantage of both antioxidant and pH responsive attributes. Aronia addition did not affect the thermal stability of guar gum films. Radical scavenging activity of the films (%) was measured by 2,2‐Diphenyl‐1‐picrylhydrazyl (DPPH) assay, and aronia added films exhibited very strong antioxidant activity (up to 85%). The colour of aronia solution varied from pink to brown with pH ranging from 1 to 13. Similarly, when the films were immersed in buffer solutions at different pH values, the visual colour varied from pink to brownish yellow. ΔE values of GR_AR_3 (guar gum films having the highest aronia concentration) ranged between 23.31 and 40.62 at pH 1–13. This result proved colour change of the films can be even detected by untrained consumers. Furthermore, the films were found to be very sensitive to ammonia vapour. Aronia incorporated guar gum films could be suggested as both antioxidant films to prevent foods oxidation from oxidation and promising intelligent films to monitor the deterioration of foods.
Nigerian women seeking asylum in England on grounds of sexual violence
Authors: Ajayi Chinyere Elsie 
Published: June 2023

AbstractThis study aims to give voice to the experiences of Nigerian women seeking asylum in the UK on the grounds of sexual violence. It draws upon in‐depth narrative interviews with 10 Nigerian women, aged between 27 and 46, seeking asylum on the grounds of sexual violence. Women's accounts were analysed thematically, and the contextual factors that influenced the outcome of their asylum claims were explored. Findings show that women's asylum applications were affected by factors relating to lack of evidence, use of words and/or phrases that do not align with the English language meaning of sexual violence, Home Office's lack of understanding of cultural issues specific to women and peculiarity of women's narrative construction and the decommissioning of legal assistance. Findings also suggest that asylum organisations play a key role in providing holistic support to women. Recommendations are made for the Home Office's policies following these findings.
The high costs of outsourcing: Vendor errors, customer mistreatment, and well‐being in call centers
Authors: O'Brady Sean , Doellgast Virginia , Blatter David 
Published: June 2023

AbstractWe analyze the impact of outsourcing on the well‐being of internal call center employees in the U.S. telecommunications industry. Our findings draw on mixed‐methods data. The qualitative findings suggest that internal employees experienced escalating job demands connected to errors by third‐party call center vendors and their employees due to additional work and intensified customer frustrations. SEM results show sequential mediation between the time internal employees spent correcting vendor errors, customer mistreatment of employees, emotional exhaustion, job satisfaction, and absenteeism. Employee autonomy over customer‐related decisions appeared to help workers manage these job demands and their effects on well‐being.
RETRACTED: Wound cosmesis problems and other postoperative problems of laparoscopic compared to open paediatric inguinal hernia repair: A meta‐analysis
Authors: Li Qiyu , Liu Siyuan , Ma Xuemei , Yu Jiaping 
Published: June 2023

AbstractA meta‐analysis research was executed to appraise the wound cosmesis problems and other postoperative problems of laparoscopic compared to open paediatric inguinal hernia (IH) repair. Inclusive literature research until March 2023 was done and 869 interconnected researches were revised. The 11 picked researches enclosed 3718 paediatric inguinal hernia were in the utilised researches' starting point, 1948 of them were utilising laparoscopic IH repairs, and 1770 were utilising open IH repairs. Odds ratios (ORs) in addition to 95% confidence intervals (CIs) were utilised to appraise the wound cosmesis problems and other postoperative problems of laparoscopic compared to open paediatric IH repairs by dichotomous approaches and a fixed or random model. Laparoscopic IH repairs had significantly lower wound cosmesis problems (OR, 0.29; 95% CI, 0.16–0.52, P < .001), metachronous contralateral inguinal hernia (MCIH) (OR, 0.11; 95% CI, 0.03–0.49, P = .003), recurrence (OR, 0.34; 95% CI, 0.34–0.99, P = .04) and postoperative problems (OR, 0.35; 95% CI, 0.17–0.73, P = .005), and higher wound score (OR, 12.80; 95% CI, 10.09–15.51, P < .001) compared to open paediatric IH. Laparoscopic IH repairs had significantly lower wound cosmesis problems, MCIH, recurrence, and postoperative problems, and a higher wound score compared to open paediatric IH. However, when interacting with its values, caution must be taken since much of the research had low sample sizes.
Scale dependency in fish beta diversity–hydrology linkages in lowland rivers
Authors: Rolls Robert J. , Wolfenden Ben , Heino Jani , Butler Gavin L. , Thiem Jason D. 
Published: June 2023

AbstractAimA key aspect of biodiversity research is to determine the environmental drivers affecting the degree to which ecological assemblages vary in space (beta diversity). The strength and significance of environmental drivers of beta diversity is, however, influenced by the spatial extent over which beta diversity is assessed. Beta diversity of riverine biota is affected by flow variability. We examined hydrology–beta diversity relationships at two spatial extents (reaches vs. entire systems) within rivers to determine if relationships with hydrological variables are scale dependent or generalisable across spatial scales.LocationMurray–Darling Basin, Australia.TaxonFreshwater fish.MethodsFish assemblage data were sourced from two monitoring programmes that sampled sites annually during 2014–2019 and spanned either reaches (<100 km) or the broader ‘system’ extent (>1000 km) of five tributaries. Beta diversity was examined by calculating pairwise (incidence and abundance) dissimilarities for each year to compare temporal trends in beta diversity. Multi‐site dissimilarities were modelled against hydrological variables using beta regression.ResultsInter‐annual change in assemblage composition was detected only at the extent of river reaches but not at the extent of river systems. Temporal variation in within‐river beta diversity showed inconsistent patterns when compared between the two spatial extents. Within‐river beta diversity relationships with hydrological gradients were inconsistent among rivers. Overall, statistical models explained much more variation in within‐river beta diversity when assessed at the reach extent when compared to broader river system extents.Main ConclusionsOur findings highlight that changes in within‐river beta diversity are likely to depend on the spatial extent of sampling. Furthermore, inconsistent beta diversity–hydrology relationships among rivers suggest that both empirical evidence and theoretical predictions adopted in ecohydrology may not be transferable among river systems.
Environmental and structural factors driving poor quality of care: An examination of nursing homes serving Black residents
Authors: Travers Jasmine L. , Castle Nicholas , Weaver Susan H. , Perera Uduwanage G. , Wu Bei , Dick Andrew W. , Stone Patricia W. 
Published: June 2023

AbstractBackgroundPoor quality of care in nursing homes (NHs) with high proportions of Black residents has been a problem in the US and even more pronounced during the COVID‐19 pandemic. Federal and state agencies are devoting attention to identifying the best means of improving care in the neediest facilities. It is important to understand environmental and structural characteristics that may have led to poor healthcare outcomes in NHs serving high proportions of Black residents pre‐pandemic.MethodsWe conducted a cross‐sectional observational study using multiple 2019 national datasets. Our exposure was the proportion of Black residents in a NH (i.e., none, <5%, 5%–19.9%, 20–49.9%, ≥50%). Healthcare outcomes examined were hospitalizations and emergency department (ED) visits, both observed and risk‐adjusted. Structural factors included staffing, ownership status, bed count (0–49, 50–149, or ≥150), chain organization membership, occupancy, and percent Medicaid as a payment source. Environmental factors included region and urbanicity. Descriptive and multivariable linear regression models were estimated.ResultsIn the 14,121 NHs, compared to NHs with no Black residents, NHs with ≥50% Black residents tended to be urban, for‐profit, located in the South, have more Medicaid‐funded residents, and have lower ratios of registered‐nurse (RN) and aide hours per resident per day (HPRD) and greater ratios of licensed practical nurse HPRD. In general, as the proportion of Black residents in a NH increased, hospitalizations and ED visits also increased.Discussion/ImplicationsAs lower use of RNs has been associated with increased ED visits and hospitalizations in NHs generally, it is likely low RN use largely drove the differences in hospitalizations and ED visits in NHs with greater proportions of Black residents. Staffing is an area in which state and federal agencies should take action to improve the quality of care in NHs with larger proportions of Black residents.
A note on the social efficiency of free entry in Cournot oligopoly in a pure network goods market
Authors: Toshimitsu Tsuyoshi 
Published: June 2023

AbstractWe explore the social efficiency of free entry in a pure network goods market where Cournot oligopolistic competition prevails and consumers have passive expectations. Focusing on network compatibility between firms, we consider the cases of two network systems: a firm‐specific system and a single industry‐wide network system. We demonstrate the following results. In the firm‐specific network system, the number of firms under free entry is socially excessive compared with the second‐best criteria. However, in the single industry‐wide network system, if the elasticity of network effects in relation to the expected network sizes is sufficiently large, the number of firms under free entry is socially insufficient compared with the second‐best criteria. Otherwise, socially excessive entry arises. We also examine the same issue in the case of a mixed network goods market.