bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the Health and Fitness Benefits of a 6-Month FES-Cycling Program on a Recumbent Trike for Individuals with Motor Complete SCI: A Pilot Study
Authors: Sanna* Nicole , Nossa* Roberta , Biffi Emilia , Guanziroli Eleonora , Diella Eleonora , Ferrante Simona , Molteni Franco , Peruzzo Denis , Nicola Casali , Alfonso Mastropietro , Rizzo Giovanna , Tarabini Marco , Pedrocchi Alessandra , Ambrosini Emilia 
Published: January 2025

Abstract

Background: Spinal cord injury (SCI) severely affects physical function, leading to muscle atrophy and reduced bone density. Sport-therapy, incorporating recreational and competitive activities, has shown promise in enhancing recovery for individuals with SCI. Functional Electrical Stimulation (FES)-cycling combines exercise benefits with stimulation advantages, and recent integration with mobile recumbent trikes adds further potential. This study aimed to evaluate the effects of a 6-month FES-cycling sport therapy using a recumbent trike on individuals with motor complete SCI.
Methods: Five participants engaged in bi-weekly FES-cycling sessions using an instrumented recumbent trike. A comprehensive assessment was conducted before training, at 3 and 6 months of training, and at 1-month follow-up. Outcome measures included maximal muscle Cross-Sectional Area (maxCSA) from Magnetic Resonance Images, bone mineral density, clinical scales, and questionnaires on spasticity, pain, bowel dysfunction, psychological well-being, and sport motivation. Additionally, maximal power output and cycling endurance were assessed.
Results: The FES-cycling program led to a significant increase in muscle mass of 34% after 6 months of training, correlated to an improved cycling performance (maxCSA versus peak power). A slight decrease of muscle mass was observed as expected at follow-up. Participants reported high well-being and strong motivation throughout the training program. Bone health, spasticity, bowel dysfunction, and pain levels did not significantly change overall.
Conclusions: FES-cycling on a recumbent trike shows potential as a therapeutic and recreational activity for individuals with SCI. It significantly improved muscle mass and physical performance while positively impacting psychological well-being and motivation. Further research with larger cohorts is necessary to confirm these benefits and optimize protocols, establishing FES-cycling as a valuable sport-therapy model for SCI.
Trial registration: The study protocol was retrospectively registered on clinicaltrials.gov (NCT06321172) due to technical issue.
Experimental Study on the Mechanical Properties and Deformation Failure Characteristics of Sandstone under Graded Equal Amplitude Cyclic Loading and Unloading
Authors: NI Zhiwei , Li Jie , Qin Ke , WU Xiaogang , ZHU Junxing , ZHOU Shiming 
Published: January 2025

Abstract

To investigate the effects of graded equal amplitude cyclic loading on rock deformation and failure, this study examines the influence of confining pressure and upper limit cyclic stress on the deformation parameters, stress-strain hysteresis curves, and macroscopic failure characteristics of sandstone during cyclic loading and unloading processes. Through a series of three-stage cyclic loading and unloading tests conducted under varying confining pressures, the findings indicate the following: The stress-strain curves of cyclic loading and unloading exhibit concave shapes, with closely aligned curves. As the confining pressure and upper limit stress increase, the hysteresis loop curves become progressively sparser, with their areas expanding. Low confining pressures and upper limit stresses inhibit the growth of circumferential strain. Compared to conventional triaxial tests, the peak strength, circumferential peak strain, and elastic modulus of sandstone decrease under cyclic loading and unloading conditions, whereas the peak axial strain increases. The Poisson's ratio initially decreases and then increases with increasing confining pressure. Under cyclic loading, both the crack initiation stress and damage stress surpass those observed in conventional triaxial tests. In both test conditions, the rock samples exhibit distinct brittle failure characteristics, with macroscopic failure modes predominantly manifesting as shear failure. However, cyclic loading and unloading inhibit microcrack formation. The findings elucidate the deformation and failure mechanisms of sandstone under graded equal amplitude cyclic loading and unloading, offering valuable insights for evaluating engineering stability.
Analysis and comparison of the trends in burden of injury in China and ASEAN countries from 1990 to 2021 and its association with the socio-demographic index
Authors: Nie Feiyang , Bai Xinyu , Liang Wenjie , Ma Zhenyu 
Published: January 2025

Abstract

Background
As China and the Association of Southeast Asian Nations (ASEAN) experience rapid economic growth and urbanization, injuries have become a significant public health issue. This study aims to analyze and compare the injury burden trends in these regions from 1990 to 2021, while examining the correlation with the Socio-Demographic Index (SDI).
Methods
Data from the Global Burden of Disease Study 2021 (GBD 2021) was used to assess injury burden metrics such as incidence, prevalence, mortality, and disability-adjusted life years (DALYs). Joinpoint regression analysis identified trends, while frontier analysis assessed the optimal scenario for managing injury burden relative to the SDI. Health inequality was analyzed using the Slope Index of Inequality (SII) and Concentration Index (CI).
Results
The study revealed a mixed picture of injury burden trends. While overall trends showed a decrease in injury incidence, prevalence, mortality, and DALYs, certain periods and countries experienced increases. Unintentional injuries remained the predominant cause. The injury burden shifted to older adults, particularly those aged 70 and above, reflecting the demographic shift towards an aging population, with males bearing a higher burden compared to females. The injury burden was strongly correlated with the SDI, indicating a decrease as countries develop. In the frontier analysis examining the correlation between injury burden and the SDI, countries furthest from the global frontier fit line were predominantly those with middle to high SDI rankings. This finding suggests that countries with higher SDI levels exhibit a more substantial potential for advancing health burden mitigation efforts. The SII for DALYs decreased from − 2407.96 in 1990 to -1159.885 in 2021, indicating a reduction in the disparity of age-standardized injury burden between high-income and low-income countries.
Conclusions
The study provides valuable insights into the injury burden trends and disparities in China and ASEAN countries. It underscores the importance of addressing social determinants of injury risk and emphasizes the need for tailored interventions considering regional disparities and evolving age distributions. By leveraging these findings, policymakers and stakeholders can develop more effective strategies to reduce the socio-economic burden of injuries, contributing to the achievement of Sustainable Development Goals related to injury prevention.
How Thinking About God Transforms Self Recognition and AI Preferences Among Christians and Shintoists in Japan
Authors: Hitsuwari Jimpei , Hayashi Takechika , Du Meiyi , Nomura Michio 
Published: January 2025

Abstract

This study investigated how God saliency affects self-recognition and AI preferences across different Japanese religions, via two studies: a three-religion comparison (N=168) and a focused examination of Christians and Shintoists (N=120). Participants wrote about God or daily activities and completed measures of the small self, human imperfection, human imperfection acceptance, divine love, evaluation of AI-generated art, and investment decisions. Results showed that God salience consistently increased the small self across both studies; however, unlike previous Western findings, it did not affect perceptions of human imperfections or AI preferences. Notably, animistic tendencies emerged as significant predictors of the small self (Study 1) and imperfection acceptance (Study 2), suggesting that viewing the divine as more intimate and equal, rather than absolute, shapes these relationships in the Japanese context. These findings highlight how cultural and religious backgrounds influence the relationship between religious thought and AI preferences, demonstrating the need for culturally diverse perspectives.
Tunable porosity in a hydrogel with extreme vibration damping properties
Authors: Scarpa Fabrizio , Day Graham , Zhang Qicheng , Remillat Chrystel , Comandini Gianni , Perriman Adam 
Published: January 2025

Abstract

We have developed hydrogel systems with tunable porosity through dialysis casting by varying alginate and poloxamer compositions from 0% to 10%. These gels feature diverse porosity topologies, yielding loss factors between 16% and 29% in the 50 Hz to 300 Hz frequency range. The dynamic modulus shows a remarkable increase of over an order of magnitude, reaching approximately 3 MPa compared to the static modulus. Vibration transmissibility tests and dynamic mechanical analysis reveal that the poroelastic and pneumatic-like effects from the tunable porous structures contribute significantly to this damping effect. Furthermore, these hydrogels are biosourced and biodegradable, providing a sustainable alternative to conventional fossil-based damping materials.
Gut microbiota metabolic reprogramming in metastatic prostatic cancer: prognostic value in patients under androgen receptor pathway inhibitors therapy.
Authors: Castro Sonia María Pérez , Quinta Manuel Carballo , Rodríguez Adrián Freire , Núñez Carlos Daviña , Pereira Alejandro Bellas , Alvargonzález Jorge Julio Cabrera , Schoch Miguel Pérez , Costas Nahir Rodríguez , Arteaga Carlos Andrés Muller , García Juan Francisco Sánchez , Outeda Enrique Cespon , Diez Maria Elena López 
Published: January 2025

Abstract

Metastatic prostate cancer (MPCa) is considered an aggressive condition. The objective was to elucidate the link between gut microbiota (GM) derived metabolites and disease progression in MPCa. Fecal microbiome shallow shotgun metagenomics of 15 patients with MPCa receiving ARPIs therapy were studied. A control group of 39 patients with untreated PCa was included. ARPIs-driven changes in the GM leading to functional redundancy in testosterone synthesis were observed. The GM could be contributing to epithelial–mesenchymal transition and MPCa progression by the increased synthesis of microbial-derived acetate. The feature-level analysis revealed that Bifidobacterium longum was enriched in the patients in aprogression stage (LinDA coefficient 5.7) whereas Sutterella wadsworthensis, Butyricimonas, Bilophila wadsworthia, Alistipesindistinctus, Bacteroides thetaiotaomicron and Intestinimonas were depleted (LinDA coefficient -7.2, -5.1, -4.4, -3.9, -3.9and -2.9, respectively). Bifidobacterium longum, Butyricimonas, Butyricimonas faecihominis, Bilophila sp. and Bacteroides thetaiotaomicron abundances were predictive of progression (AUC 0.88, 0.92, 0.88, 0.93 and 0.86, respectively, DESeq2; p <0.00001). A deeper understanding of the multifaceted roles of intestinal microorganisms at various stages of the disease would be of crucial importance to achieve an overall perspective of the individual prognosis of MPCa.
Predicting Student Satisfaction in Career Choices Using Machine Learning: A Case Study
Authors: Oubraime Mohamed , M’Hamdi Ahmed , Sabour Abderrahim 
Published: January 2025

Abstract

Student satisfaction is crucial for making successful educational and career choices. This study explores how artificial intelligence, specifically the Support Vector Machine (SVM) model, can help predict student satisfaction with their university choices by considering socio-economic, environmental, and cultural factors. We analyzed data from 125 students at a technology university through three main steps: first, we assessed the reliability of a satisfaction measurement tool; second, we identified key factors influencing satisfaction through statistical analysis; and third, we applied an SVM model to predict satisfaction, using 70% of the data for training and 30% for testing. Our results revealed significant positive correlations between student background, social support, prior knowledge, and their preference for group work with their overall satisfaction. The SVM model was able to predict satisfaction with an accuracy of 89%. These findings highlight the value of AI in educational guidance and suggest that the SVM model can effectively predict student satisfaction, as well as other factors critical to academic and career success.
ARMANDO DE HOLANDA E A INDÚSTRIA
Authors: Afonso Alcília 
Published: January 2025

O texto trata sobre a obra arquitetônica industrial produzida por Armando de Holanda (1940-1979), nascido na cidade de Canhotinho, Pernambuco, nordeste do Brasil, e conhecido em nível nacional pelo seu livro “Roteiro para Construir no Nordeste", publicado em 1976, que se converteu em uma referência na área projetual, propondo princípios para se projetar uma arquitetura nos trópicos. Pretende trazer à tona a produção arquitetônica industrial da Holanda, ainda pouco estudada, observando como os princípios projetuais propostos pelo arquiteto, que priorizou sistemas de industrialização e soluções climáticas na arquitetura, estão presentes em seus projetos industriais das dezenas de fábricas projetadas e construídas em diversos estados do Nordeste, como Pernambuco, Paraíba, Piauí, Sergipe, financiados pela política de desenvolvimento da região nordeste proposta pela SUDENE/ Superintendência de Desenvolvimento do Nordeste. Justifica-se apresentar algumas das soluções projetuais feitas pelo arquiteto, a fim de socializar as pesquisas inéditas na área que enfoca sua produção arquitetônica industrial moderna, e que adotam em sua prática, os princípios propostos e presentes em seus textos, principalmente no publicado em 1966, intitulado "Sobre uma arquitetura de sistemas". A pesquisa faz parte de estudos em andamento desenvolvido pela autora sobre os projetos industriais do arquiteto, buscando observar as soluções projetuais e construtivas dessas obras produzidas com base na modernidade arquitetônica e seus princípios projetuais.
Scrutinizing the Gateway Relationship Between Gaming and Gambling Disorder: Scoping Review With a Focus on the Southeast Asian Region
Authors: Siste Kristiana , King Daniel L , Hanafi Enjeline , Sen Lee Thung , Adrian Adrian , Murtani Belinda Julivia 
Published: January 2025

Abstract

Background
The gaming and gambling overlap has intensified with new evidence emerging. However, the relationship between gaming and gambling in the digital space is still inconclusive, especially in resource-limited Asian countries.

Objective
This study aims to review available evidence on the possible interaction and focuses specifically on the gateway interaction between gambling and gaming. Additionally, this review delves into the state of evidence from the Southeast Asian region, providing an in-depth analysis of this underexplored area.

Methods
We performed a scoping review by sifting through the publications in five databases. We focused on the gateway interaction and provided a possible pathway model, while two other convergence relationships were provided for comparison.

Results
The scoping review identified a total of 289 publications, with the majority being empirical (n=181), although only 12 studies used longitudinal designs. A significant proportion of the publications (n=152) concentrated on the correlation or comorbidity between gaming and gambling. Most of the evidence has originated from Global North countries, with very limited research emerging from Southeast Asia (n=8). The most commonly studied gambling-like element in video games was loot boxes (n=105). Other elements investigated included esports betting, skin betting, token wagering, gambling advertisements, and gambling-like features. Several longitudinal studies have highlighted the risk of the gateway effect associated with gamblification involvement. However, emerging evidence suggests more nuanced underlying mechanisms that drive the transition from gaming to gambling.

Conclusions
Overall, there is early evidence of linkage between gambling and gaming, through shared structural and biopsychosocial characteristics. This association possibly extends beyond disparate comorbidity, as such engagement in one activity might influence the risk of partaking in the other behavior. The field requires further longitudinal data to determine the directionality and significant precipitating factors of the gateway effect, particularly evidence from Asia.
Case-Based Virtual Reality Simulation for Severe Pelvic Trauma Clinical Skill Training in Medical Students: Design and Pilot Study
Authors: Teng Peng , Xu Youran , Qian Kaoliang , Lu Ming , Hu Jun 
Published: January 2025

Background
Teaching severe pelvic trauma poses a significant challenge in orthopedic surgery education due to the necessity of both clinical reasoning and procedural operational skills for mastery. Traditional methods of instruction, including theoretical teaching and mannequin practice, face limitations due to the complexity, the unpredictability of treatment scenarios, the scarcity of typical cases, and the abstract nature of traditional teaching, all of which impede students’ knowledge acquisition.

Objective
This study aims to introduce a novel experimental teaching methodology for severe pelvic trauma, integrating virtual reality (VR) technology as a potent adjunct to existing teaching practices. It evaluates the acceptability, perceived ease of use, and perceived usefulness among users and investigates its impact on knowledge, skills, and confidence in managing severe pelvic trauma before and after engaging with the software.

Methods
A self-designed questionnaire was distributed to 40 students, and qualitative interviews were conducted with 10 teachers to assess the applicability and acceptability. A 1-group pretest-posttest design was used to evaluate learning outcomes across various domains, including diagnosis and treatment, preliminary diagnosis, disease treatment sequencing, emergency management of hemorrhagic shock, and external fixation of pelvic fractures.

Results
A total of 40 students underwent training, with 95% (n=38) affirming that the software effectively simulated real-patient scenarios. All participants (n=40, 100%) reported that completing the simulation necessitated making the same decisions as doctors in real life and found the VR simulation interesting and useful. Teacher interviews revealed that 90% (9/10) recognized the VR simulation’s ability to replicate complex clinical cases, resulting in enhanced training effectiveness. Notably, there was a significant improvement in the overall scores for managing hemorrhagic shock (t39=37.6; 95% CI 43.6-48.6; P<.001) and performing external fixation of pelvic fractures (t39=24.1; 95% CI 53.4-63.3; P<.001) from pre- to postsimulation.

Conclusions
The introduced case-based VR simulation of skill-training methodology positively influences medical students’ clinical reasoning, operative skills, and self-confidence. It offers an efficient strategy for conserving resources while providing quality education for both educators and learners.
Mobilitas Sosial dan Kesejahteraan Masyarakat Buruh PLTU
Authors: Rosana Ellya , Astuti Yuliana Widi 
Published: January 2025

Kebutuhan manusia yang semakin kompleks memaksa seseorang harus terus berusaha untuk mencari pekerjaan demi bisa memenuhi kebutuhan primer dan sekunder. untuk bisa memenuhi kebutuhan tersebut manusia melakukan perubahan-perubahan dalam mencapai kehidupan yang lebih baik. Dalam penelitian ini, gerak perubahan yang dimaksud oleh peneliti adalah perubahan atau peralihan mata pencaharian masyarakat yang mengalami mobilitas menjadi buruh industri PLTU. Mobilitas sosial secara tidak langsung akan berdampak pada kesejahteraan pelaku mobilitasnya. Berdasarkan permasalahan diatas penulis merumuskan beberapa rumusan masalah. tentang proses mobilitas sosial buruh PLTU dan PLTU dalam meningkatkan kesejahteraan masyarakat desa Tarahan. Metode penelitian dalam skripsi ini adalah deskriptif kualitatif dengan menggunakan jenis penelitian lapangan (Field reserch). Adapun sifat dari penelitian ini adalah Deskriptif yaitu penulis akan mendeskripsikan data temuan lapangan. Metode pengumpulan data berupa observasi dimana peneliti mengamati secara langsung dilapangan, wawancara dan dokumentasi. Dalam wawancara yang digunakan kepada informan menggunakan teknik purposive sampling. Teori yang digunakan untuk menganalisis dalam penelitian ini adalah teori tindakan sosial yang dikemukakan oleh Max Weber. Hasil penelitian ini menunjukan bahwa proses mobilitas sosial masyarakat sehingga menjadi buruh di industri PLTU dikarenakan beberapa faktor pendorong yaitu, faktor ekonomi, faktor penggusuran lahan, faktor iklim dan faktor keahlian seseorang. PLTU memiliki peran yang sangat besar dalam upaya meningkatkan kesejahteraan sosial keagamaan masyarakat desa melalui program-program yang dimiliki, yaitu, program pertanian, program ternak bergilir, subsidi pembangunan sarana dan prasarana desa, program sunat massal, program berbagi di bulan ramadhan, Program Sumur Bor Dan Kamar Mandi Permanen dan program pemotongan hewan qurban
Musical Expression of Islamic Identity: The Syncretism of Blangikhan Ritual in Lampung
Authors: Aryandari Citra , Chaniago Delsi 
Published: January 2025

The Blangikhan ritual underscores the significance of dignity within Lampung's culture, where the community is renowned for its hospitality and compassion towards one another. Blangikhan is a celebration and reflects community values, norms, and beliefs. This study aims to comprehend and explore the intertwined musical practices in the Blangikhan tradition of the Lampung community's religious and cultural identity. The researcher explores the correlation between the music produced in the Blangikhan tradition and the strengthening of Islamic identity among the community. The research utilized an ethnographic method. The data collection techniques were observation, interview, literature study, and documentation. The result concludes that music is an integral component of this event and reflects the Islamic Identity within Lampung's culture. The music in this ritual encompasses various genres, including Hadrah music, a religious musical tradition with sholawat lyrics, the music accompanying the Bedana dance that blends Malay-Islamic nuances, and even pop music with religious themes. This research delves deeper into how music in the Blangikhan ritual mirrors the Islamic identity and how the Lampung community incorporates Islamic elements into their performing arts. The study also considers how the production of this music influences the representation of Islamic identity within the Blangikhan ritual. This research holds significant relevance in comprehending how culture and religion can interact and shape identity within a cultural ritual context.