bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does servant leadership affect organisational citizenship behaviour? Mediating role of affective commitment and moderating role of role identity of young volunteers in non-profit organisations
Authors: Ngah Nor Syamaliah , Abdullah Nor Liza , Mohd Suki Norazah , Kasim Mohd Ariff 
Published: August 2023

PurposeThis study examines the relationships between servant leadership and organisational citizenship behaviour (OCB) of young volunteers in non-profit organisations (NPOs) and investigates the mediating role of affective commitment and the moderating role of role identity in this relationship.Design/methodology/approachSelf-administered questionnaires were distributed to 400 young volunteers from NPOs in Malaysia. Data were analysed using the partial least squares-structural equation modelling (PLS-SEM) approach.FindingsThe results reveal that affective commitment significantly mediates the relationship between servant leadership and OCB of young volunteers in NPOs. The role of identity was found to moderate the relationship between servant leadership and affective commitment of young volunteers in NPOs.Research limitations/implicationsThis study utilised servant leadership theory and examined the direct effect between servant leadership and OCB of young volunteers in NPOs, the mediating effect of affective commitment, and the moderating effect of role identity in this relationship simultaneously within a unified research framework.Practical implicationsNPOs should recruit more servant leaders and provide effective volunteer training and leadership development to current leaders to increase affective commitment and develop better service behaviours in dealing with volunteers.Originality/valueThis study is unique in that it highlights the partially mediated effects of affective commitment on the relationships between servant leadership and OCB of young volunteers in NPOs, as well as the fact that role identity significantly moderates the relationship between servant leadership and affective commitment of young volunteers in NPOs.
Blockchain technology-based crypto assets: new insights into the evolution of the understanding of digital entrepreneurship
Authors: Ulrich Klaus , Guaita Martínez José Manuel , Carracedo Patricia , Soriano Domingo Ribeiro 
Published: August 2023

Purpose The study aims to shed light on the concepts most addressed in scientific research, which blockchain topics are of most interest, how relevant are these tools for academia, and how relevant are they?Design/methodology/approach The authors have developed a bibliometric study of scientific publications on blockchain made since 2016. For the analysis, the VOSViewer software version 1.6.19 has been used, which allows a statistical analysis of scientific publications on the subject.Findings The study manifest the relevance of Initial Coin Offering, growth of research interest in this field and the relevance of blockchain technology in the development of entrepreneurial projects.Originality/value This study provides a complete and updated picture of the scientific research on blockchain for the subsequent transfer of knowledge to the business world.
Does Islamic corporate governance prevent bankruptcy in Islamic banks? Implications for economic sustainability
Authors: Jan Ahmad Ali , Lai Fong-Woon , Shah Syed Quaid Ali , Tahir Muhammad , Hassan Rohail , Shad Muhammad Kashif 
Published: August 2023

PurposeSustainability is essential to the ongoing operations of banks, though it is much less clear how Islamic corporate governance (ICG) promotes economic sustainability (ES) and thereby prevents bankruptcy. To explore the unexplored, this study aims to examine the efficacy of ICG in preventing bankruptcy and enhancing the ES of Islamic banks operating in Pakistan.Design/methodology/approachThe current study measures ES through Altman's Z-score to analyze the level of the industry's stability and consequently examines the effect of ICG on the ES of Islamic banks in Pakistan for the post-financial-crises period. Using the country-level data, this study utilized a fixed-effect model and two-stage least squares (2SLS) techniques on balanced panel data spanning from 2009 to 2020 to provide empirical evidence.FindingsThe empirical results unveiled that board size and meetings have a significant positive influence on the ES while managerial ownership demonstrated an unfavorable effect on ES. Interestingly, the insignificant effect of women directors became significant with the inclusion of controlled variables. Overall, the findings indicate that ICG is an efficient tool for promoting ES in Islamic banks and preventing them from the negative effects of emerging crises.Practical implicationsThe findings provide concrete insights for policymakers, regulators and other concerned stakeholders to execute a sturdy corporate governance system that not only oversees the economic, social and ethical aspects but also provides measures to alleviate the impacts of potential risks like the COVID-19 pandemic.Social implicationsExamining the role of ICG in alleviating bankruptcy risk is an informative and useful endeavor for all social actors.Originality/valueTo the best of the authors’ knowledge, this study is one of the first efforts to provide evidence-based insights on the role of ICG in preventing bankruptcy and offers a potential research direction for ES.
Board of directors and financial performance: the role of risk management in Palestinian-listed companies
Authors: Musallam Sami R.M. 
Published: August 2023

PurposeThis study aims to investigate the effect of the board of directors on financial performance, either directly or indirectly through the existence of risk management after the issuance of the Palestinian Code on Corporate Governance (PCCG) in Palestine.Design/methodology/approachThis study presents an empirical investigation of 31 nonfinancial Palestinian-listed companies from 2010 to 2016. This study utilizes the structural equation modeling (SEM) model.FindingsThe results of the SEM model find that there is a significant positive effect of the existence of risk management and the tenure-Chief Executive Officer (CEO) on financial performance. However, CEO duality has a significant negative effect on financial performance. The results also find that the effect of CEO duality and board size are significantly positive on financial performance through the existence of risk management.Research limitations/implicationsThis study adds to the existing literature by investigating the effect of the board of directors on financial performance, either directly or indirectly through the existence of risk management in Palestine as one of the youngest stock exchanges in the region that assists in testing the validity of agency theory in a young and small emerging Islamic market context.Practical implicationsThe results of this paper are significant to shareholders and managers of companies to make proper choices in order to secure the interests of stakeholders and increase the flow of capital and foreign investment.Originality/valueTo the best of the authors’ knowledge, it is one of the first papers to investigate the effect of the board of directors and financial performance, either directly or indirectly through the existence of risk management in Palestine.
Introversion-extraversion and online course satisfaction
Authors: Hayat Tsahi , Samuel-Azran Tal , Goldberg Shira , Amichai-Hamburger Yair 
Published: August 2023

PurposeThe 2020 Coronavirus pandemic forced universities to hastily transition to eLearning on a mass scale, necessitating the identification of populations who are more challenged by the transition. This study aims to identify how students’ level of introversion/extraversion and digital literacy come to play in their satisfaction with the eLearning environment.Design/methodology/approachThe analysis examined 272 Israeli students who moved from a face-to-face learning environment to a Zoom learning environment between March–July 2020, following the outbreak of the pandemic. All the participants completed two rounds of surveys, and 62 of the 272 participants were then interviewed, and their social network was mapped using a sociogram.FindingsFindings indicated that, in accordance with the “poor get richer” hypothesis, introverts expressed more satisfaction from the transition to the video-conferencing Zoom platform than extraverts. In addition, for highly introverted people, high digital literacy was significantly associated with increased course satisfaction, whereas for highly extraverted people, a high number of social ties with peers from the course was associated with course satisfaction.Originality/valueAs expected, the study’s findings shows that there is no “one size fits all” approach for online learning. Learners with different personalities can benefit from learning environments that foster greater satisfaction with the learning experience. Online platforms can, and should, be designed in a way that offers this needed personalization, and this study provides initial principles that can inform such personalization.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/OIR-01-2023-0028
Framework for using online social networks for sustainability awareness
Authors: Chalmeta Ricardo , Barbeito-Caamaño Adriana M. 
Published: August 2023

Purpose This study aims to contribute to the field of computer systems for sustainability research. It proposes a framework for sustainability awareness using online social networks (OSNs) by analyzing major research streams of the current state of knowledge and different bibliometric variables, and identifies a future research agenda in the field.Design/methodology/approach The preferred reporting items for systematic review and meta-analysis (PRISMA) methodology, content analysis and bibliometric tools were employed to identify, select, collect, synthesize, analyze and evaluate all research published on sustainability awareness using OSNs to provide complete insight into this research area.Findings This study proposed a framework comprising four categories for sustainability awareness using OSNs. These four categories are: the key factors to success, analysis of existing tools, proposal of new methods, approaches and theoretical frameworks, and case examples. In addition, this study synthesized the future research challenges for each category of the proposed framework.Originality/valueFostering sustainability awareness and sustainable behavior using OSNs is a growing area of research that seeks cultural change in society to achieve sustainable development. Through OSNs, people can discover and become aware of the consequences of unsustainable practices and habits in society, and learn how to develop sustainable behavior.Peer reviewThe peer review history for this article is available at https://publons.com/publon/10.1108/OIR
Does gamification affect knowledge-sharing behavior? The mediating role of intrinsic satisfaction needs
Authors: Cai Yang , Li Xiujun , Shi Wendian 
Published: August 2023

PurposeThis study employed self-determination theory (SDT) and the “Motivational affordance–Psychological outcomes–Behavioral outcomes” framework to investigate the relationship between gamification features and knowledge-sharing behavior in online communities.Design/methodology/approachA theoretical model was tested with 281 Chinese users from an online social question and answer (Q&A) community. Partial least square structural equation modeling was applied to analyze the data.FindingsThe empirical results revealed that competence mediated the effects of immersion and achievement-related gamification features on knowledge sharing. Moreover, relatedness mediated the effects of immersion, achievement and social-related gamification features on knowledge sharing.Research limitations/implicationsThis study was conducted on a Chinese Q&A platform, and the results may not be generalizable to other cultures or service providers with different goals.Practical implicationsThe study's findings indicate that gamification could serve as an effective toolkit for incentivizing and promoting knowledge sharing in online communities. The findings thus provide strategic insights for administrators of online communities seeking to leverage gamification designs to encourage user participation in knowledge-sharing activities.Originality/valueResearch on the role of gamification in promoting knowledge sharing has been limited in scope and has focused on tourism comment communities. Little evidence exists on the effect of gamification within social Q&A communities. Further, the finding of gamification's positive role in motivating knowledge sharing indicates the need for the knowledge-sharing field to focus on contextual factors.
An unusual case of a triple suicide pact at the time of the COVID‐19 pandemic
Authors: Raddi Silvia , Tarozzi Ilaria , Cecchetti Matteo , Chericoni Silvio , Franceschetti Lorenzo , Bugelli Valentina 
Published: August 2023

AbstractIn December 2020, the World Health Organization (WHO) declared SARS‐CoV2 a global pandemic. Home confinement, low social contacts, and fear of virus transmission played a major role as risk factors for suicides during the following period. Suicide pacts, in particular, showed a different pattern. A rare case of a triple suicide pact among members of the same family nucleus is presented. The victims were an elderly, severely ill woman and her adult children (a son and daughter), linked by a morbid relationship. The last time the family was seen alive was 40 days before the discovery. All corpses presented decompositional changes. After a full autopsy, the cause of death was determined to be a lethal intake of morphine for the mother and acute blood loss due to self‐stabbing at the neck for the siblings. The younger woman was under the effects of a large amount of heparin. Toxicological analysis was positive for opioids and alcohol in both siblings. Suicide pacts have rarely been described during the COVID‐19 pandemic. In the few cases reported, the victims were more often relatives than people in a romantic relationship. The involvement of three people is unusual, as is the use of different suicide methods among the victims. In the presented case, the elderly mother's imminent death from terminal cancer, her concern over dying in a nondomestic environment, and the siblings' fear of being alone likely led to the conception of the suicide pact. Social isolation and economic difficulties also played a contributing role.
ELF1/PRR11/ARP2/3 promoted trophoblast cells proliferation and motility in early pregnancy
Authors: Zhu Pengfei , Dou Chengli , Song Zhijiao , Bi Xingyu , Wu Xueqing , Miao Yiliang 
Published: August 2023

AbstractBackground/objectiveEarly pregnancy loss (EPL) is a common adverse pregnancy outcome with an incidence of approximately 10–30%. There are many factors that cause EPL, among which the lack of proliferation and invasive properties of trophoblast cells can lead to embryonic development. Therefore, in this study, the molecular biology of trophoblast cells was investigated.MethodsPlacental villous tissues from EPL patients were collected to explore ELF1 and PRR11 gene expression. The proliferation and migration of trophoblast cells were assessed by MTT, crystalline violet staining, and traswell assays, respectively. Western blotting and RT‐qPCR were performed to investigate the relationship between ELF1, PRR11, and ARP2/3. F‐actin polymerization and FAK activation were evaluated by immunofluorescence and western blotting. Ultimately, ELF1/PRR11/ARP2/3 expression was verified in the EPL mice modelResultsELF1 and PRR11 were lowly expressed in placental villous tissues from EPL. The overexpression of ELF1 and PRR11 promoted proliferation and migration of trophoblast cells. Moreover, while ELF1 bound to the PRR11 promoter and promoted transcriptional activation. Finally, ELF1/PRR11/ARP2/3 showed low expression in the placental tissue of EPL mice.ConclusionOur study suggested that PRR11 promoted the motility of trophoblast cells by binding to the ARP2/3 complex to promote F‐actin polymerization and FAK activation. In addition, ELF1 bound to the initiation site of PRR11 to promote its transcription. ELF1/PRR11/ARP2/3 may play an important role in EPL.
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
Authors: Thomasius Friederike , Pesta Dominik , Rittweger Jörn 
Published: August 2023

AbstractDespite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios. Here, we discuss the potential of current pharmacological strategies. Bone loss in space is fuelled by bone resorption. Alendronate, an oral bisphosphonate, reduced bone losses in experimental bed rest and space. However, gastrointestinal side effects precluded its further utilization in space. Zoledronate (a potent bisphosphonate), denosumab (RANKL antagonist) and romosozumab (sclerostin antagonist) are all administered via injection. They effectively suppress bone resorption and are routinely prescribed against osteoporosis. Their serious adverse effects, namely, osteonecrosis of the jaw and atypical femur fractures occur very rarely when the usage is limited to 1 or 2 years. Hence, utilization of one of these compounds may outweigh the bone risks of space travelling, in particular in those with high bone resorption rates. Muscle wasting in space is likely due to hampered muscle protein synthesis. Even though this might theoretically be countered by the synthesis‐boosting effects of anabolic steroids, the practical grounds for such recommendation are currently weak. Moreover, they reveal their full potential only when combined with an anabolic exercise stimulus, for example, via strength training. It therefore seems that a combination of exercise and pharmacological countermeasures should be considered for musculoskeletal health on the way to the Moon and Mars and back.
A Proportional Incidence Rate Model for Aggregated Data to Study the Vaccine Effectiveness Against COVID-19 Hospital and ICU Admissions
Authors: Yan Ping , Mullah Muhammad Abu Shadeque , Tuite Ashleigh 
Published: August 2023

AbstractWe develop a proportional incidence model that estimates vaccine effectiveness (VE) at the population level using conditional likelihood for aggregated data. Our model assumes that the population counts of clinical outcomes for an infectious disease arise from a superposition of Poisson processes with different vaccination statuses. The intensity function in the model is calculated as the product of per capita incidence rate and the at-risk population size, both of which are time-dependent. We formulate a log-linear regression model with respect to the relative risk, defined as the ratio between the per capita incidence rates of vaccinated and unvaccinated individuals. In the regression analysis, we treat the baseline incidence rate as a nuisance parameter, similar to the Cox proportional hazard model in survival analysis. We then apply the proposed models and methods to age-stratified weekly counts of COVID-19–related hospital and ICU admissions among adults in Ontario, Canada. The data spanned from 2021 to February 2022, encompassing the Omicron era and the rollout of booster vaccine doses. We also discuss the limitations and confounding effects while advocating for the necessity of more comprehensive and up-to-date individual-level data that document the clinical outcomes and measure potential confounders.
Update on the role of T cells in cognitive impairment
Authors: Ruiz‐Fernández Ignacio , Sánchez‐Díaz Raquel , Ortega‐Sollero Enrique , Martín Pilar 
Published: August 2023

AbstractThe central nervous system (CNS) has long been considered an immune‐privileged site, with minimal interaction between immune cells, particularly of the adaptive immune system. Previously, the presence of immune cells in this organ was primarily linked to events involving disruption of the blood–brain barrier (BBB) or inflammation. However, current research has shown that immune cells are found patrolling CNS under homeostatic conditions. Specifically, T cells of the adaptive immune system are able to cross the BBB and are associated with ageing and cognitive impairment. In addition, T‐cell infiltration has been observed in pathological conditions, where inflammation correlates with poor prognosis. Despite ongoing research, the role of this population in the ageing brain under both physiological and pathological conditions is not yet fully understood. In this review, we provide an overview of the interactions between T cells and other immune and CNS parenchymal cells, and examine the molecular mechanisms by which these interactions may contribute to normal brain function and the scenarios in which disruption of these connections lead to cognitive impairment. A comprehensive understanding of the role of T cells in the ageing brain and the underlying molecular pathways under normal conditions could pave the way for new research to better understand brain disorders.LINKED ARTICLESThis article is part of a themed issue From Alzheimer's Disease to Vascular Dementia: Different Roads Leading to Cognitive Decline. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v181.6/issuetoc
MicroRNA‐326 negatively regulates CD155 expression in lung adenocarcinoma
Authors: Nakanishi Takayuki , Yoneshima Yasuto , Okamura Koji , Yanagihara Toyoshi , Hashisako Mikiko , Iwasaki Takeshi , Haratake Naoki , Mizusaki Shun , Ota Keiichi , Iwama Eiji , Takenaka Tomoyoshi , Tanaka Kentaro , Yoshizumi Tomoharu , Oda Yoshinao , Okamoto Isamu 
Published: August 2023

AbstractTreatment with immune checkpoint inhibitors induces a durable response in some patients with non‐small‐cell lung cancer, but eventually gives rise to drug resistance. Upregulation of CD155 expression is implicated as one mechanism of resistance to programmed death receptor‐1 (PD‐1)/PD‐1 ligand (PD‐L1) inhibitors, and it is therefore important to characterize the mechanisms underlying regulation of CD155 expression in tumor cells. The aim of this study was to identify microRNAs (miRNAs) that might regulate CD155 expression at the posttranscriptional level in lung cancer. Comprehensive miRNA screening with target prediction programs and a dual‐luciferase reporter assay identified miR‐346, miR‐328‐3p, miR‐326, and miR‐330‐5p as miRNAs that bind to the 3′‐UTR of CD155 mRNA. Forced expression of these miRNAs suppressed CD155 expression in lung cancer cell lines. Immunohistochemical staining of CD155 in tissue specimens from 57 patients with lung adenocarcinoma revealed the median tumor proportion score for CD155 to be 68%. The abundance of miR‐326 in these specimens with a low level of CD155 expression was significantly greater than in specimens with a high level (p < 0.005). Our results thus suggest that miR‐326 negatively regulates CD155 expression in lung adenocarcinoma and might therefore play a role in the development of resistance to PD‐1/PD‐L1 inhibitors.