bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Photocatalytic Properties Of The Nb2O5@rGO For The Degradation Of Methylene Blue
Authors: Al-Marri Abdulhadi Hamad , Janene Fatma , Moulahi Ali , Mogharbel Amal T. , Al-Farraj Eida S. , Al-Mohaimeed Amal M. , Mjejri Issam 
Published: June 2023

Abstract

Mixing the advantages of nano- Nb2O5 and reduced graphene oxide (rGO), composite systems offer great potential of exploration. Herein, Nb2O5 nanoparticles (NPs) and Nb2O5 modified reduced graphene oxide (Nb2O5@rGO) urchin-like have been successfully synthesized by hydrothermal process. The materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Raman spectroscopy, Nitrogen adsorption-desorption isotherms and UV–vis diffuse reflectance spectroscopy. The photocatalytic efficiency of the Nb2O5 NPs and Nb2O5/rGO urchin like were evaluated with respect to the degradation of methylene blue (MB) under solar radiation. It is found that the Nb2O5/rGO with porous structure and high specific surface area of ~ 105.25 m2/g shows significantly superior photocatalytic performances for the removal of the MB dye (99% degradation after 1h illumination) than pure Nb2O5 (20% degradation after 1h illumination). The improvement in the photocatalytic properties of the composite material is mainly ascribed to a cooperative effect between the rGO with good electrical conductivity and the unique nano-porous structure of Nb2O5 with abundant catalytic active sites, superior charge transfer efficiency, and stronger oxidation property.
Evaluation of Neck Ultrasound Measurements as a Difficult Airway Predictor
Authors: Köse Elif Özge Çınar , Tekin Murat , Cesur Sevim , Çam İsa , Baykara Zehra Nur 
Published: June 2023

Abstract
Objective
It was aimed to investigate the relationship between cervical measurements and difficult airways using ultrasonographic measurements.
Methods
American Society of Anesthesiologists(ASA) grade I to III, male or female, 120 adult patients, undergoing elective surgery were included in the study. The distance of the trachea, cricoid cartilage, thyroid cartilage, vocal cord anterior commissure, and hyoid bone to the skin was measured by placing the 10–13 MHz linear ultrasound probe in the transverse plane. The length of the cricothyroid and thyrohyoid membranes and their distance from the skin were measured by placing the probe in the sagittal plane. An other experienced anesthesiologist performed mask ventilation and intubation of the patient after the patient's induction of general anesthesia. During this procedure, the patient was evaluated for difficult mask ventilation, difficult laryngoscopy, and difficult intubation.
Results
28 (23.3%) patients had a difficult airway. Considering the measurements with the difficult airway, the best predictor was the epiglottis midline-skin distance (AUC(Area under the curve):0.847 p < 0.0001 Cut-off:>19.9 Sensitivity:78.6% Specificity:79.4%). Hyoid bone to skin distance, thyroid cartilage to skin distance, thyrohyoid membrane to skin distance and vocal cord anterior commissure-skin distance also predicted difficult airway.
Conclusion
The increase in the distance of the epiglottis midline, vocal cord anterior commissure, hyoid bone, thyrohyoid membrane, and thyroid cartilage to the skin at the level of the isthmus measured by ultrasonography is predictive of difficult airways. According to the results of our study, we believe that ultrasonographic evaluation can be used in the prediction of difficult airways.
ClinicalTrials.gov ID and date:
NCT05347121 / 21.04.2022
The relaxed eddy acumulation method
over the Amazon forest: the importance
of flux strength on individual and aggregated flux estimates.
Authors: Dias Nelson Luís , Toro Ivan Mauricio Cely , Dias-Júnior Cléo Quaresma , Mortarini Luca , Brondani Daiane 
Published: June 2023

Abstract
The ability of the Relaxed Eddy Accumulation (REA) method to estimate
the kinematic fluxes of temperature, water vapor and carbon dioxide
was assessed for the dry season (3 months) at the ATTO (Amazon Tall
Tower Observatory) site from turbulence measurements. The
measurements were performed at 50 m above ground within the roughness
sublayer. Non-conformity with inertial sublayer conditions was
confirmed one more time by analyzing dimensionless scalar standard
deviations. Recently found results that the REA method outperforms
Monin-Obukhov-based approaches are confirmed. Over the scale of the
whole dry season, REA and EC (eddy covariance) estimates are essentially
equal. However, we also verify that such results fail to reveal
significant variability and scatter of the REA estimates when the
fluxes are of small magnitude. On the basis of previous studies, we
conjecture that this is caused by a likely imbalance between scalar
gradient production and molecular dissipation. Confirmation of our
results to trace gases, therefore, requires further study.
Reactions to Science Communication: Social Network Topic Using Word Embeddings and Semantic Knowledge
Authors: de Lima Bernardo Cerqueira , Baracho Renata Maria Abrantes , Mandl Thomas , Porto Patricia Baracho 
Published: June 2023

Abstract
Social media platforms that disseminate scientific information to the public during the COVID-19 pandemic highlighted the importance of the topic of scientific communication. Content creators in the field, as well as researchers who study the impact of scientific information online, are interested in how people react to these information resources. This study aims to gain insights into how the public perceives scientific information, and how their behavior towards science communication (e.g. through videos or texts) during the pandemic is related to their information-seeking behavior. To analyze public reactions to scientific information, the study focused on Twitter users who are doctors, researchers, science communicators, or representatives of research institutes, and analyzed their replies for 2 years from the start of the pandemic. One large challenge consists in sifting through social media data to find comments related to a reaction towards scientific content that might prove useful feedback to a content creator. The study aimed in developing a solution powered by topic modelling enhanced by manual validation and other machine learning techniques, such as word embeddings, that is capable of filtering massive social media datasets in search of documents related to reactions to scientific communication. This architecture can be replicated for finding any documents related to niche topics in social media data.
Novel Optimal Staggered Grid Finite Difference Scheme Based on Gram–Schmidt Procedure for Acoustic Wave Modelling
Authors: Zhang Min , Zhou Liming , Fu Daiguang , Dong Shiqi , Wu Haibo 
Published: June 2023

Abstract

The staggered grid finite difference method is widely used in the numerical simulations of acoustic equations; however, its application is accompanied by numerical dispersion. The most representative traditional method for suppressing the numerical dispersion is the Taylor expansion method, which mainly converts the acoustic equation into a polynomial equation of the trigonometric function and then expands the trigonometric function into a power function polynomial through the Taylor expansion to finally obtain the difference coefficient. However, this traditional method is only applicable to the small wavenumber range. In view of this, we used the Gram–Schmidt orthogonalization method, combined with the binomial theorem and Euler formula, to reverse the polynomial of power function into a polynomial of trigonometric function and finally obtain a new difference coefficient. To highlight the effectiveness of our new method, we compared it with the Taylor expansion and least-squares methods by selecting a small wavenumber, middle wavenumber, and wide wavenumber ranges. First, accuracy and dispersion analyses were conducted, and the results showed that the new difference coefficient generated smaller errors and induced stronger suppression of the numerical dispersion. We conducted a comparative analysis of the uniform and complex models, which further validated the superiority of the proposed staggered grid difference coefficient.
Livestock Breeding, Conservation and Genomics in Brazil: Who, When, Where, and What
Authors: McManus Concepta , Albuquerque Lucia Galvão , Dias Laila Talarico , Paiva Samuel Rezende , Pimentel Daniel , Pimentel Felipe 
Published: June 2023

Abstract
We examined Brazilian animal breeding and genetics publishing patterns to identify the major research groups and where they publish. Data was collected in Scopus and analysed in Vosviewer (version 1.615, 2020). The analyses showed that this area of knowledge is centred on groups in São Paulo state universities. Most research is on classical quantitative genetics published in Brazilian journals with a lower impact (impact factor lower than the world mean of one). Beef cattle are the main species researched, with dairy cattle and sheep also present. Less information is available on goats, poultry, swine, and equines. Research must expand to regions outside São Paulo State and beyond classical quantitative genetics. Publishing should be directed towards international journals and an increase in international collaborations. We also use the data to discuss and suggest new research areas to improve Brazil´s food security and increase sustainable animal production.
EMPOWERING ISLAMIC PHILANTHROPY TOWARDS SUSTAINABILITY DEVELOPMENT GOALS YAYASAN DANA SOSIAL AL-FALAH SURABAYA
Authors: Musafa'ah Suqiyah , Arif Mohammad , Mustofa Imron 
Published: June 2023

Abstrak: Penelitian ini membincangkan beberapa kondisi masyarakat terkait stabilitas dan keberlangsungan hidup. Berbasis standar Sustainable Development Goals (SDGs). Peneliti berfokus pada kiprah lembaga pengelola filantropi Islam, Yayasan Dana Sosisa al-Falah (YDSF). Hadirnya penelitian ini membawa dua permasalah utama: sistematika pengelolaan aset umat dan implementasi standar SDGs bidang pemberdayaan manusia. Riset ini merupakan kajian kualitatif berbasis data lapangan dengan pendekatan fenomenologis. Kajian ini sampai pada dua kesimpulan. Pertama, YDSF mengenalkan model fundrasing donatur sebagai pengepul sekaligus agent of branding. Bentuk distribusi bantuannya bervariasi: konsumtif tradisional; konsumtif kreatif; produktif tradisional; dan produktif kreatif. Kedua, YDSF mengimplementasikan sistem mustaḥiq to muzakkī (M-to-M). Pemberdayaan yang dilakukan YDSF berprinsip kreditur harus bisa menjadi debitur untuk masyarakat luas. Bentuk pembedayaannya pun bervariasi sesuai kebutuhan yang dirasa para kreditur paling urgent untuk diimplementasikan.
Abstract: This paper discusses several conditions of society ‘stability and survival’standards-based Sustainable Development Goals (SDGs). Research focuses on the work of Islamic philanthropic management institutions, Yayasan Dana Sosial al-Falah (YDSF). The research brings two main problems: systematics of asset management and implementation of SDGs standards in the field of human empowerment. This research is a qualitative study, Based on field data with a phenomenological approach. The study came to two conclusions. First, YDSF brings a fundraising model of donors as collectors and agents of branding the forms of distribution: traditional consumptive; creative consumptive; traditional productive; and creatively productive. Second, YDSF implements the system mustaḥiq to muzakkī (M-to-M). The empowerment carried out by YDSF is based on the principle that creditors must be able to become debtors for the wider community. The form of empowerment also varies according to the needs felt by creditors most urgently to implement.
Satellite-based investigation of water stress at the basin scale: an integrated analysis of downscaled GRACE estimates and remotely sensed data
Authors: Khorrami Behnam 
Published: June 2023

Abstract

Freshwater availability is a very determining issue, especially in semiarid and arid regions, for sustainable development and secured food production. In this premise, the detection and assessment of water stress are of utmost importance. In this study, the satellite-based Potential Available Water Storage (PAWS) index is used to test its feasibility for a basin-scale analysis of water stress in the Western Mediterranean Basin (WMB) in Türkiye. The coarse-resolution GRACE (Gravity Recovery And Climate Experiment) estimates were downscaled based on the Random Forest (RF) model and then were integrated with fine-resolution precipitation data to derive fine-resolution PAWS values. The accuracy of the index was validated against the net water flux (NWF) and water storage deficit (WSD) values over the basin. The results revealed a good performance for the PAWS index for a local scale evaluation of water stress. The PAWS variations turned out to be highly correlated with the NWF (r = 0.72) and WSD (r = 0.66). The PAWS indicates that the WMB has suffered from a critical hydrological situation from 2003 to 2020 during which the basin has been under stress with the most critical situation in 2018 when the per capita water has fallen below 500 m3 suggesting an absolute water stress status.
Experimental investigation of gabion broad-crested weirs under upstream partial blockage conditions
Authors: Hasanian Shirvan Sanaz , Pirzadeh Bahareh , Rajaei Seyed Hosein , Shafai Bejestan Mahmood 
Published: June 2023

Abstract
The attention of researchers and engineers has been attracted to gabion weirs due to their environmental, hydraulic, and stability capabilities compared with solid weirs. One of the possible problems of the weirs is the partial blockage caused by sedimentation upstream of them. This research experiment investigates the hydraulic performance of gabion broad-crested weirs (GBCWs) with an upstream partial blockage. For this purpose, a total of 147 experiments were studied with different conditions for free-flow conditions. The weirs were tested with five partial blockage conditions between 0% and 100% of the weir height (0, 0.25P, 0.5P, 0.75P, and P). The results showed that increasing the partial blockage decreases the discharge coefficient. The changes in the discharge coefficients are minor for partial blockage less than 0.25P, and for partial blockage greater than 0.5P, the discharge coefficients are significantly reduced. As the partial blockage increases, the effect of filling-material size in gabion weirs decreases. Finally, a relationship was developed using the nonlinear regression analysis approach to estimate the discharge coefficient in the GBCWs with partial blockage.
miR-488-3p Represses Malignant Behaviors and Facilitates Autophagy of
Osteosarcoma Cells by Targeting Neurensin-2
Authors: Yun Chao , Zhang Jincai , Morigele  
Published: June 2023

Objective:
Osteosarcoma (OS) is a primary bone sarcoma that primarily affects children
and adolescents and poses significant challenges in terms of treatment. microRNAs (miRNAs)
have been implicated in OS cell growth and regulation. This study sought to investigate the
role of hsa-miR-488-3p in autophagy and apoptosis of OS cells.

Methods:
The expression of miR-488-3p was examined in normal human osteoblasts and OS cell
lines (U2OS, Saos2, and OS 99-1) using RT-qPCR. U2OS cells were transfected with miR-488-
3p-mimic, and cell viability, apoptosis, migration, and invasion were assessed using CCK-8, flow
cytometry, and Transwell assays, respectively. Western blotting and immunofluorescence were
employed to measure apoptosis- and autophagy-related protein levels, as well as the autophagosome
marker LC3. The binding sites between miR-488-3p and neurensin-2 (NRSN2) were predicted
using online bioinformatics tools and confirmed by a dual-luciferase assay. Functional rescue
experiments were conducted by co-transfecting miR-488-3p-mimic and pcDNA3.1-NRSN2
into U2OS cells to validate the effects of the miR-488-3p/NRSN2 axis on OS cell behaviors. Additionally,
3-MA, an autophagy inhibitor, was used to investigate the relationship between miR-
488-3p/NRSN2 and cell apoptosis and autophagy.

Results:
miR-488-3p was found to be downregulated in OS cell lines, and its over-expression
inhibited the viability, migration, and invasion while promoting apoptosis of U2OS cells. NRSN2
was identified as a direct target of miR-488-3p. Over-expression of NRSN2 partially counteracted
the inhibitory effects of miR-488-3p on malignant behaviors of U2OS cells. Furthermore, miR-
488-3p induced autophagy in U2OS cells through NRSN2-mediated mechanisms. The autophagy
inhibitor 3-MA partially reversed the effects of the miR-488-3p/NRSN2 axis in U2OS cells.

Conclusion:
Our findings demonstrate that miR-488-3p suppresses malignant behaviors and promotes
autophagy in OS cells by targeting NRSN2. This study provides insights into the role of
miR-488-3p in OS pathogenesis and suggests its potential as a therapeutic target for OS treatment.
Medicinal Plants and Natural Products to Treat Obesity through Inhibiting Pancreatic Lipase: A Review (2020-2022)
Authors: Jamai Khaoula , Daoudi Nour Elhouda , Elrherabi Amal , Bnouham Mohamed 
Published: June 2023

:
Pancreatic lipase is an enzyme that catalyzes the hydrolysis of triglycerides to monoglycerides
and free fatty acids which promote and accelerate their absorption by the intestine, thus leading to obesity.
Drugs that have numerous side effects explain the beneficial medicinal effect of plants resulting from
their Phyto molecules that exhibit strong anti-lipase activity. The present review reveals the medical
treatment and consequently the associated side effects. It also represents an update of various medicinal
plants and their metabolites that act as lipase inhibitors published between (2020-2022). We have discussed
93 species belonging to 48 different plant families and numerous bioactive molecules exerting this
activity. We have compared 29 species for their anti-lipase potential. Fabaceae and Lamiaceae were the
most dominant with 7 species, and the highest percentage (95%) for pancreatic lipase inhibitory activity
was recorded by “Filipendula kmtaschatia” from Rosaceae family while “Piper betle” from Piperaceae
family showed the lowest percentage (15.9%). The medical treatments with low dose effect were liraglutide
saxenda (3mg/day), also flavonoids, in particular catechin derivatives, which were the most potent
in terms of pancreatic lipase inhibitory activity with the lowest IC50s. This study summarized medical and
natural treatments that are used to treat obesity through inhibiting pancreatic lipase and delaying fat assimilation
in the intestines. So far, more studies are needed for the use of these as herbal medicine for
obesity.

Conclusion:
This study summarized medical and natural treatments that are used to treat obesity through inhibiting pancreatic lipase and delaying fat assimilation in the intestines. So far, more studies are needed for the use of these as herbal medicine for obesity.
Recent Progress in Synthetic Chemistry and Biological Activities of Pyrimido[
4,5-b] Quinoline Derivatives (Part III)
Authors: Gouda Moustafa A. , Abu-Hashem Ameen A. , Ameen Tahah A. , Salem Mohammed A. , Aljuhani Ateyatallah 
Published: June 2023

Abstract:
Amongst heterocyclic compounds, quinoline and pyrimidine are advantaged scaffolds that
appear as significant assembly motifs for the development of new drug entities. Moreover, quinolinepyrimidine-
inspired hybrids have a number of biological characteristics that are known. In addition,
many pyrimido[4,5-b]quinoline ring systems (PyQs4,5-b), specifically concerning medicinal chemistry,
have been reported over the past decade. The synthesis of (PyQs4,5-b) using barbituric acid, thiobarbituric
acid, pyrimidine, and their derivatives is presented in this review. The preparation of
PyQs4,5-b was clarified through the following chemical reactions: Friedländer, Vilsmeier-Haack
formylation, Hantzsch-like reaction, and one-pot three-component reaction.
Reactive Oxygen Species Induced Hepatic Cellular Carcinoma: A Protective
Role of Nano-antioxidant
Authors: Kesharwani Roohi , Patel Dilip Kumar , Verma Pankaj , Kumar Vikas 
Published: June 2023

Abstract:
Hepatocellular carcinoma (HCC) is the fifth most common form of cancer worldwide and
the third most common cause of cancer-related death. In the beginning period, healing medicines, for
example, careful resection, liver transplant and neighborhood removal, can improve the patient’s endurance.
Be that as it may, the infection is identified in the cutting-edge stage; also, some accessible
treatments are confined to palliative consideration and nearby treatment. Assessed the dietary benefit of
some normal cell reinforcement specialists that help the capacity of the body coming about an improvement
of the well-being and insurance from various ailments; our audit will give an updated status
of the various parts of HCC the board through covering the viability and the advantageous impacts of
various regular operators and their system of activity against HCC for the future treatment modalities.
In this review, we talk about the ongoing advances identified with the reason (featuring the principle
hazard factors), treatment, and result in hepatocellular carcinoma.
Virtual Screening of Flavonoids against Plasmodium vivax Duffy Binding
Protein Utilizing Molecular Docking and Molecular Dynamic Simulation
Authors: Yasir Muhammad , Park Jinyoung , Han Eun-Taek , Park Won Sun , Han Jin-Hee , Kwon Yong-Soo , Lee Hee-Jae , Chun Wanjoo 
Published: June 2023

Background:
Plasmodium vivax (P. vivax) is one of the highly prevalent human malaria
parasites. Due to the presence of extravascular reservoirs, P. vivax is extremely challenging to
manage and eradicate. Traditionally, flavonoids have been widely used to combat various diseases.
Recently, biflavonoids were discovered to be effective against Plasmodium falciparum.

Methods:
In this study, in silico approaches were utilized to inhibit Duffy binding protein (DBP),
responsible for Plasmodium invasion into red blood cells (RBC). The interaction of flavonoid
molecules with the Duffy antigen receptor for chemokines (DARC) binding site of DBP was investigated
using a molecular docking approach. Furthermore, molecular dynamic simulation studies
were carried out to study the stability of top-docked complexes.

Results:
The results showed the effectiveness of flavonoids, such as daidzein, genistein,
kaempferol, and quercetin, in the DBP binding site. These flavonoids were found to bind in the
active region of DBP. Furthermore, the stability of these four ligands was maintained throughout
the 50 ns simulation, maintaining stable hydrogen bond formation with the active site residues of
DBP.

Conclusion:
The present study suggests that flavonoids might be good candidates and novel
agents against DBP-mediated RBC invasion of P. vivax and can be further analyzed in in vitro
studies.