bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating adsorptive potential of Raphanus caudatus leaves biomass for methyl orange dye: isotherm and kinetic study
Authors: Naseem Khalida , Arif Muhammad , Anwar Aneela , Haider Sajjad , Akhtar Muhammad Saeed 
Published: June 2023

Abstract
This study emphasis the removal of methyl orange (MO) from aqueous medium by Raphanus caudatus powdered leaves biomass. Functional groups involved in the removal of MO dye from aqueous medium by leave biomass were identified by Fourier transform infrared (FTIR) spectroscopy analysis. It was seen that removal of dye molecules from aqueous medium was affected by the change in adsorption condition such as adsorbent dose, agitation time and pH of the medium. Maximum adsorption capacity of Raphanus caudatus leave biomass powder for MO dye was found as 30.86 mg/g. Regression factor (R
2) value indicates the best fitting of Langmuir isotherm model for the adsorption process. Amount of adsorption energy calculated by Dubinin-Radushkevich (DR) isotherm model illustrates the chemical bond formation between dye and biomass particles. Recyclability results depict that biomass showed good adsorption capacity value for MO up to 4th reusability cycle.
Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-Like Phenotype
Authors: Xiong Wenchao , Jin Liqiang , Zhao Yulu , Wu Yu , Dong Jinghua , Guo Zhixin , Zhu Minzhen , Dai Yongfeng , Pan Yida , Zhu Xinhong 
Published: June 2023

Hereditary spastic paraplegia (HSP) is a severe neurodegenerative movement disorder, the underlying pathophysiology of which remains poorly understood. Mounting evidence has suggested that iron homeostasis dysregulation can lead to motor function impairment. However, whether deficits in iron homeostasis are involved in the pathophysiology of HSP remains unknown. To address this knowledge gap, we focused on parvalbumin-positive (PV+) interneurons, a large category of inhibitory neurons in the central nervous system, which play a critical role in motor regulation. The PV+interneuron-specific deletion of the gene encoding transferrin receptor 1 (TFR1), a key component of the neuronal iron uptake machinery, induced severe progressive motor deficits in both male and female mice. In addition, we observed skeletal muscle atrophy, axon degeneration in the spinal cord dorsal column, and alterations in the expression of HSP-related proteins in male mice withTfr1deletion in the PV+interneurons. These phenotypes were highly consistent with the core clinical features of HSP cases. Furthermore, the effects on motor function induced byTfr1ablation in PV+interneurons were mostly concentrated in the dorsal spinal cord; however, iron repletion partly rescued the motor defects and axon loss seen in both sexes of conditionalTfr1mutant mice. Our study describes a new mouse model for mechanistic and therapeutic studies relating to HSP and provides novel insights into iron metabolism in spinal cord PV+interneurons and its role in the regulation of motor functions.SIGNIFICANCE STATEMENTIron is crucial for neuronal functioning. Mounting evidence suggests that iron homeostasis dysregulation can induce motor function deficits. Transferrin receptor 1 (TFR1) is thought to be the key component in neuronal iron uptake. We found that deletion ofTfr1in parvalbumin-positive (PV+) interneurons in mice induced severe progressive motor deficits, skeletal muscle atrophy, axon degeneration in the spinal cord dorsal column, and alterations in the expression of hereditary spastic paraplegia (HSP)-related proteins. These phenotypes were highly consistent with the core clinical features of HSP cases and partly rescued by iron repletion. This study describes a new mouse model for the study of HSP and provides novel insights into iron metabolism in spinal cord PV+interneurons.
Batik, Lengkeng, Zat Warna Alam PEMANFAATAN DAUN LENGKENG (Nephelium Logan) UNTUK PEWARNA BATIK
Authors: Amantika Ravika Setyo , Syamwil Rodia , Nurrohmah Siti 
Published: June 2023

UTILIZATION OF LEAF LITCHI (NEPHELIUM LOGAN) FOR BATIK DYES.
Abstract : The purpose of this study to determine whether the leaves litchi can be used as natural dye for batik cloth. This research uses experimental method and the result in laboratory test to see the quality of dyeing result with leaf litchi. The analysis used that is analysis descriptive on all results test laboratory . The object of this research is leaf litchi , primissima mori cloth that has been batik, type mordan (alum, lime tohor, tunjung). Leaf extraction process litchi with type different mordant showing existence difference old age color on fabric morri that is without mordan produce most young color with value the mean T% 44,32, with alum with value the mean T% 46,71, then chalk with value the mean T% 77.79, and tunjung produce The oldest color with value average of TT% 94.02. Conclusions can be explained that leaf litchi can be used as a source of natural dyes in bati k and the type of mordan used can affect the direction of the resulting batik color
Keywords: Batik, Leaf litchi (Nephelium logan) , Natural Color Substance
APD (MASKER) COVID-19 UNTUK PENYANDANG DIFABLE
Authors: Russanti Irma , Rohmah Lailatul , Kharnolis Mein 
Published: June 2023

Masker merupakan alat pelindung diri yang penting saat ini, penggunaan masker dapat menekan penyebaran virus COVID-19. Desain masker yang ada tidak dapat digunakan oleh semua orang terutama para difabel. Pengembangan desain masker diperlukan para difabel selain untuk melindungi diri juga memberikan kenyamanan dalam berkomunikasi.Tujuan penulisan artikel ini untuk mengetahui desain, bahan, dan daya pakai masker COVID-19 bagi difabel. Untuk mendapatkan studi literatur ini dilakukan pencarian jurnal tentang desain, bahan, dan daya pakai masker yang baik untuk perlindungan masyarakat dan melindungi dari penyebaran droplet (cairan) yang diperoleh dari Google Scholar, Research Gate, Mendeley, dan PubMed mulai dari tahun 2017 hingga 2020 dan mendapatkan lebih dari 10 jurnal.Hasil studi literature menunjukkan bahwa bahan masker COVID-19 bagi difabel memiliki dua bahan yaitu bahan katun dan bahan mika dengan quilter cotton,desain masker COVID-19 bagi difabel memiliki bagian transparan pada bagian mulut, dan daya pakai masker COVID-19 bagi difabel yang baik memberikan perlindungan terhadap droplet dan kenyamanandalam berkomunikasi.
Assessment of the microbiological status of two Hungarian ostrich farms
Authors: Brassó Dóra Lili , Knop Renáta , Várszegi Zsófia , Bársony Péter , Komlósi István , Bacsadi Árpád , Bistyák Andrea 
Published: June 2023

AbstractThe aim of this study was to estimate the occurrence of bacterial infection and contamination in two ostrich-producing farms. Compared to other poultry species, the hatchability of ostrich eggs is especially low. In a quest to identify factors that may affect hatchability, we collected faecal samples from adult birds, as well as eggs with dead-in-shell embryos, dead chicks and swab samples from the surface of the eggs and from the environment. The samples were screened for the presence of bacteria by routine bacteriological culture methods. The most prevalent bacteria, detected in the samples, were Escherichia coli, Bacillus spp. and coliform bacteria, whereas Pseudomonas spp. were less frequently found. The intensity and species compositon of the bacterial contamination was comparable in the two farms. Our results revealed that the bacteria, present in the environment, may likely be transmitted to the surface of the eggs. If they are able to penetrate the shell then the embryos and chicks become infected easily. These findings draw the attention to the special importance of enforcing efficient decontamination and disinfection measures to keep the environment and egg surface free from germs. Besides the appropriate egg treatment procedure, the incubation and hatching technology should also be kept under control.
Exploring the complex and multifaceted interplay of the gut microbiome and cancer prevention and therapy
Authors: Kashyap Sukrit , Das Asmita 
Published: June 2023

AbstractRecent scientific research has indicated that the gut microbiota constitutes a nuanced, diverse ecosystem of microorganisms that have gained significant attention due to its crucial involvement in shaping human health and diseases. In particular, the gut microbiota plays a pivotal role in cancer prevention, and disturbances in its composition and function, known as dysbiosis, that have been linked to an increased risk of developing various malignancies. The gut microbiota exerts a myriad of effects on the production of anti-cancer compounds, the host's immune system and inflammation, underscoring its crucial involvement in cancer. Additionally, recent studies have shown that the gut microbiota has a role in the development of cancer, influencing cancer risk, co-infections, disease progression, and treatment response. The observation of reduced efficacy of immunotherapy in patients receiving antibiotic treatment indicates a substantial influence of the microbiota in mediating the toxicity and response of cancer therapy, notably immunotherapy, and its immune-related side effects. A growing body of research has focused on cancer treatments that target the microbiome, including probiotics, dietary modifications, and faecal microbiota transplantation (FMT). The forthcoming era of personalised cancer therapies is anticipated to prioritise tumor evolution, molecular and phenotypic heterogeneity, and immunological profiling, with gut microbiota assuming a pivotal position in this domain. This review aims to offer clinicians a comprehensive perspective on the microbiota-cancer axis, including its influence on cancer prevention and therapy and highlights the importance of integrating microbiome science into the design and implementation of cancer therapies.
Produção científica (2011-2021) sobre políticas públicas voltadas ao Semiárido por meio de tecnologias sociais
Authors: Monturil de Morais Fabrício Higo , Guimarães Jairo De Carvalho , Reis Lopes Wilza Gomes 
Published: June 2023

Em nível mundial, diversos estudos científicos vêm sendo publicados envolvendo políticas públicas, tecnologias para a convivência com o semiárido voltadas para a agricultura familiar, em várias áreas do conhecimento. Neste estudo tem-se como objetivo fazer uma análise cienciométrica da produção científica do período de 2011 a 2021, relacionada às políticas públicas de difusão de tecnologias de convivência com o semiárido voltadas para a agricultura familiar. A pesquisa se deu através de uma busca no Portal de Periódicos da CAPES, onde foram analisadas as principais bases de dados, periódicos, idiomas de publicação, palavras-chave e principais autores. Foram considerados apenas artigos publicados em periódicos revisados por pares, utilizando-se como palavras-chave, “agricultura familiar”, “políticas públicas” e “semiárido”, separadas pelo operador booleano AND. Foi constatado que as pesquisas são poucas, ocorrendo decréscimo a partir de 2018. Além disso, a grande maioria das pequisas realizadas concentra-se em uma única universidade do Nordeste, pelo fato de a temática ser de grande interesse para essa região. Percebe-se a necessidade de incremento na colaboração entre grupos e centros de pesquisa das diversas regiões brasileiras, e até mesmo em pesquisas e colaborações internacionais, o que pode fortalecer as políticas públicas para a Ciência, a Tecnolgia e a Inovação brasileiras.
Challenging and Reinforcing the Ability/Disability System through Advocacy for Disabled Dogs
Authors: Guenther Katja M. 
Published: June 2023

This paper illuminates how volunteers and animal rescuers who assist dogs from a high-intake public shelter in the Los Angeles metropolitan area simultaneously resist the devaluation of the lives of disabled dogs while sensationalizing and fetishizing disability through their discursive and representational practices. Drawing on observations from three years of ethnographic fieldwork in an animal shelter and with animal rescues, as well as from public media volunteers and rescuers post online, I adopt an intersectional analysis that attends to inequalities of species, ability/disability, and gender in the context of contemporary American capitalism. I show how members of the animal rescue community—who are all women, almost all white, and none of whom identified themselves as disabled—reject the shelter's practice of fast-tracking some types of disabled dogs for shelter killing and assert instead the right of disabled dogs to live. At the same time, rescuers talk about and represent disabled dogs as infantile, remarkable, and in need of saviors to help them. Ultimately, rescuers' representations of disabled dogs work to expand capitalist beliefs of companion animals as lively capital by showing that disabled dogs have value as companions, in large part through an assertion of dogs as family members.
Effectivity CaO/Hydrotalcite catalyst to biofuel microalgae Nannochloropsis sp conversion
Authors: Mirzayanti Yustia Wulandari , Zakariya Muhammad Fadkhul , Saputra Denny Angga 
Published: June 2023

Along with the rapid development of the times, the need for energy is also increasing. Fossil energy in Indonesia reaches 95% of Indonesia’s energy needs. For this reason, it is necessary to find a solution to overcome this, one of which is using renewable energy which must also be environmentally friendly. One alternative energy that has been discovered and is still being developed is biofuel. One of the raw materials that can be used for the production of biofuels is the microalgae Nannochloropsis sp. This study aimed to determine the effect of operating time on %yield and FFA of the biofuel produced and the effect of loading catalyst on %yield and FFA of the resulting biofuel. The highest %yield of crude and the lowest FFA were observed at a reaction time of 3 hours and a catalyst loading of 0.45 %wt with values of 47.981 and 0.064, respectively. The lowest %yield of crude and the highest FFA were obtained at a reaction time of 1 hourwith a catalyst loading of 0.4 %wt with values of 25.730% and 0.133, respectively.
The effect of pressure on the concentration of methane and carbon dioxide absorption in biogas
Authors: Huda Hairul , Aditya Revy , Worotikan Rivaldo Bodewyn Julian , Nurdin Nurdin 
Published: June 2023

Biogas is playing a vital role in the emerging market for renewable energy. Biogas is an alternative energy that can be used as a substitute for fossil energy. The main composition of biogas is methane gas (CH4) and carbon dioxide gas (CO2) with a small amount of hydrogen sulfide (H2S). Therefore, it is necessary to do treatment to enrich gas methane and reduce CO2 and H2S content in optimizing the use of biogas. Absorption is a CO2 capture technology often used in the chemical industry. A chemical absorption technique using a solvent solution is one of the most widely used techniques to capture CO2. This research uses MDEA (Nmethyldiethanolamine) solvent as an alkanolamine solution dissolved in water. The unit operation usually used to carry out the absorption process is an absorber, and the type of absorber used is a spray column absorber. Simulating variations in pressure on the absorber was conducted in this research. The result of this research is that the increase in pressure will increase the composition percent of CH4 in sweet gas and increase the amount of CO2 absorption in biogas. The best result of absorber pressure is obtained at a pressure of 48 bar. The purity of CH4 and %removal of CO2 in biogas can be solved simply by using the evaluation parameters of the various absorber pressures presented, which we expect to contribute to the biogas industry in the future.
Organizational Resilience from a Marketing Perspective: A Conceptual Framework
Authors: Halaby Roger , Rahi Khalil , Azoury And Nehme 
Published: June 2023

This paper explores the relationships between marketing strategies, social media platforms, the adoption and diffusion of products and services, and organizational resilience to gain an understanding of the ability of organizations to cope with disruptive events (e.g., COVID-19). This can be achieved through effective marketing strategies and the efficient use of social media platforms. In fact, resilience thinking can help organizations maintain their operations by increasing the adoption and diffusion of their products and services through the use of effective marketing strategies.
To achieve this article’s objectives, a literature review is conducted to help develop a conceptual framework that highlights a clear relationship between the previously discussed concepts. In addition, the novel nature of the relationship between marketing strategies and organizational resilience is dissected and its significance for organizations is demonstrated. In fact, the findings of this study suggest that effective marketing strategies that consider the &quot;what,&quot; &quot;who,&quot; and &quot;how&quot; dichotomies and the efficient use of social media to promote the adoption and diffusion of products and services can significantly enhance the resilience of organizations.
These relationships can serve as a starting point for further studies examining and empirically analyzing marketing strategies and their positive effect on strengthening organizational resilience.
Free-form dual-comb spectroscopy for compressive sensing and imaging
Authors: Giorgetta Fabrizio , Potvin Simon , Deschênes Jean-Daniel , Coddington Ian , Newbury Nathan , Baumann Esther 
Published: June 2023

Abstract

Time programmable frequency combs enable new measurement paradigms for dual-comb spectroscopy (DCS) that are free of many of the constraints found in traditional DCS. As opposed to fixing the repetition rate offset between combs, free-form DCS is based on full control of the temporal offset between the dual comb pulse trains, thereby enabling user-selectable sampling patterns that optimize resolution, signal-to-noise ratio, species selectivity or acquisition time. Here we show that free-form DCS enables compressive sensing. We demonstrate compressive sensing at factors up to 155, with a corresponding reduction in acquisition time, while maintaining spectral resolution. We also demonstrate molecular recurrence sampling (which can be thought of as an extreme case of compressive sensing) for detection of a single gas with >15× higher sensitivity than traditional DCS. Finally, free-form DCS can more easily enable spectral imaging since its rf signal is narrow band, in contrast to traditional DCS, and therefore compatible with the finite readout times of focal plane arrays. We demonstrate imaging of methane plumes across a 128×64 pixel focal plane at a 250 Hz rate. In the future, this flexible free-form approach can enable applications ranging from rapid open-path spectroscopy to nonlinear multidimensional comb-based spectroscopy.
Bioremediation of zinc metals and microplastics by biosynthesizing zinc oxide nanoparticles from isolated bacteria of the Caspian Sea, Iran
Authors: Haghighatjoo Motahare , Hanachi Parichehr , Mohammadi Ali , Moradlou Omran 
Published: June 2023

Abstract

The high levels of environmental pollutants like heavy metals and microplastics have prompted researchers to invent new remediation strategies, which might be accompanied by drawbacks, including the risk of secondary pollution, being costly, and inefficient. So, the aim of this study is the reduction of these environmental pollutants by the application of nanoparticle-producing bacteria. For this purpose, from 22 screened bacterial isolates of the Caspian Sea, the isolate (N1.5.2) was used to produce ZnO NPs, which were characterized by techniques like FTIR, XRD, Raman, SEM, EDX, UV-vis spectroscopy, Zeta potential, and DLS. Subsequently, different protocols of bacterial nanoparticle production (using supernatant, extract, biomass, and dilution) were compared by UV-vis spectroscopy. Then, the produced nanoparticles were applied to polystyrene microplastics to degrade them. This process was monitored by SEM and FTIR. The selected bacterial isolate (N1.5.2) was identified and its phylogenetic tree of life was depicted. The results of the blast illustrated 100% similarity of N1.5.2 to Bacillus cereus. The produced ZnO NPs peaked at 360 nm in their UV-vis spectrum. They showed a crystalline structure in the zincite phase and dispersed in the range of 171–262 nm in an aqueous environment with a PDI of 0.444 and zeta potential of -5.60 meV. Moreover, the comparative study between different production protocols has shown that ZnO nanoparticles produced by bacterial extract have higher UV-vis peak values. Furthermore, the photocatalytic activity of ZnO NPs and microplastic degradation has been proved by SEM and FTIR.
WGCNA-Based Identification of Hub Genes and Key Pathways Involved in Obesity
Authors: Yuan Yin , Sun Xuan , Wang Jinyuan , Wu Zixuan , Tian Zhikui , Zeng Xianyue , Zhang Naijin , Wang Hongwu 
Published: June 2023

Abstract
The prevalence of obesity is increasing, yet its pathogenesis and therapeutic targets are still unclear, and the efficacy of existing therapeutic modalities is limited. Therefore, it is crucial to elucidate the molecular mechanisms underlying the pathogenesis of obesity and to explore potential molecular targets for obesity drug therapy. The expression dataset (GSE73304) was downloaded from the Gene Expression Omnibus database (GEO), and the data were divided into C and P groups, which were normalized for differentially expressed genes analysis (DEGs), Gene Set Enrichment Analysis (GSEA) and weighted gene co-expression network analysis (WGCNA). The intersecting genes obtained by DEGs and WGCNA were analyzed by three machine learning methods (LASSO, RandomForest, SVM-REF), and the gene ROC curves, genetic differences between groups and correlations between genes were analyzed after obtaining the major genes. Based on WGCNA and machine learning, this study found that several genes were significantly different between healthy and obese populations and closely associated with multiple molecular mechanisms, and these genes may serve as potential targets for drug therapy and diagnostic biomarkers, which need further studies to elucidate.
Lung sounds Ventilation Cycle Segmentation and Classify Healthy Asthma and COPD
Authors: harman güneş 
Published: June 2023

Abstract
The identification of the ventilation cycle holds significant importance in clinical cases, as it provides crucial insights into respiratory patterns. Each individual breathing cycle possesses unique characteristics that are closely linked to specific pathological information. This phenomenon plays a vital role in the accurate diagnosis of respiratory diseases and aids in making informed decisions regarding the overall health status of the subject. In this particular study, the classification of subjects as either healthy or pathological asthma or COPD was performed using two popular machine learning algorithms: Artificial Neural Network (ANN) and K-Nearest Neighbor (KNN). These algorithms were employed to analyze the inspiration and expiration phases of the respiratory cycle, extracting valuable information for the classification task. By leveraging the distinctive features observed during these phases, the algorithms aimed to accurately categorize individuals based on their respiratory health. The classification results obtained from the ANN and KNN algorithms were evaluated using sensitivity, specificity, and accuracy metrics. Additionally, this study compares the actual lung sound signals that have been labeled and categorized by medical professionals (Class 1) and automatically segmented lung sound signals (Class 2). These signals are obtained through an automated segmentation process that extracts specific portions of the recorded lung sounds based on predefined criteria.