bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical, Radiological and Histological Features and Their Association with Extranodal Extension in Buccoalveolar Complex Squamous Cell Carcinoma
Authors: Anto Ronald , Riju Jeyashanth , Chinniah Praveen , Tirkey Amit Jiwan , Chamania Gaurav , Patil Shruthi , Bhandari Subhan , Paulose Antony , Vidya Konduru , Karuppusami Rekha , Babu Ramesh , Micheal Rajiv C. 
Published: August 2023

Objectives The study was aimed to (1) evaluate the effectiveness of clinical examination, intraoperative finding, and contrast-enhanced computed tomography (CECT) to detect extranodal extension (ENE) in buccoalveolar complex squamous cell carcinoma (BAOSCC), (2) to know various factors influencing ENE, and (3) to evaluate survival outcome in patients with ENE.
Materials and Methods This was a retrospective cohort study, which included 137 patients with BAOSCC who underwent curative treatment between May 2019 and April 2021. Collaborative findings suggestive of ENE were noted during preoperative clinical examination, CECT, and intraoperatively, and their efficacy was compared with postoperative histopathology. Also, the various factors associated with ENE were evaluated and compared.
Statistical Analysis Univariate and multivariate analysis of parameters was done using multiple logistic regression analysis and significant correlation was determined using chi-square test between ENE positive and negative categories. Analysis of prognosis and survival was done by Kaplan–Meier curve plotting using regression analysis and its significance was compared.
Results The overall prevalence of ENE was 18.98% and that of lymph node involvement was 40.88%. CECT (73.1%) was found to be more sensitive in detecting ENE compared to intraoperative examination (46.2%) and clinical examination (34.6%).In comparison with clinical examination (91.9%) or CECT (78.38%), intraoperative examination (93.7%) showed the highest specificity in detecting ENE. Clinical nodal size ≥ 3 cm (p ≤ 0.001), fixity (p ≤ 0.001), and clinical number of nodes (p ≤ 0.001) had significant association with ENE. The presence of thick nodal walls on CECT increased the probability of predicting ENE 15 times (p = 0.180, confidence interval: 0.3–765.4). After a mean follow-up of 18 months, subjects without nodal positivity had a survival advantage over patients with positive lymph nodes (86.4% vs. 53.3%) and those with ENE (86.4% vs. 23.2%), respectively.
Conclusion The results demonstrated that clinical examination can be used as an adjuvant to radiological imaging for prediction of ENE preoperatively. Clinical finding suggesting size of node ≥ 3 cm and ≥ 2 nodes are strong predictor of ENE, in addition to other known predictors. Patients with ENE had an unfavorable prognosis when compared with subjects with metastatic nodes without ENE. Presence of ENE remains one of the strongest factors predicting recurrence and thus poor prognosis.
Physician Attitude toward Their Attires and Laundering Habit Changes during the COVID-19: A Cross-Sectional Survey in a Tertiary Care Center
Authors: Alwabel Reema , Alasmari Bushra , Alabdulkarim Aljawhara , Chachar Yusra , Jahdali Hamdan A. , Layqah Laila , Baharoon Salim 
Published: August 2023

AbstractBackground Patient safety is of utmost importance and every effort is to be made to reduce the risk of hospital-acquired infection. Contaminated attire is proposed as a mode of hospital infections spread. This study aims to assess the laundering habits, the perception of healthcare workers toward the contamination of their attire, and the effect of coronavirus disease 2019 (COVID-19) pandemic on their cleaning practices in non-operative settings.Methods This is a cross-sectional study conducted using a self-administered questionnaire which was distributed among physicians at King Abdul-Aziz Medical city, Riyadh. The questionnaire queried the physicians about their laundering habits, knowledge toward their attire, and the difference in cleaning practices after the emergence of COVID-19.Results Out of 220 questionnaires distributed, 192 physicians responded. Majority of physicians were male (54%) and were in the 20 to 30 age group. Female gender was significantly associated with the frequency of uniform washing (p-value < 0.0001) and place of cleaning (home vs. outside home) (p-value <0.0001). Physicians in intensive care were more likely to take off their uniforms daily before leaving the hospital compared to others (p-value of 0.018). Most physicians did not prefer to use the hospital laundry system for cleaning their uniforms but consultants were the most to use it. COVID-19 pandemic led to changes in washing habits in 108 physicians (60%).Conclusion Majority of physicians accepted washing their uniforms multiple times per week and their washing habits increased during the COVID-19 pandemic. Female gender and younger physician both were associated with increasing washing habits.
A Retrospective Observational Study of Facial Dog Bite Injuries and Its Management in a Tertiary Care Center
Authors: Sreeramaraju Vulchi , Babu Vaddi Suman , Sharma Mukesh Kumar , Jha Manoj Kumar , Bhattacharya Sameek 
Published: August 2023

Abstract
Background: Facial dog bite injuries result in significant emotional, psychological, and physical trauma to the victims involved and should be considered a significant health issue. The purpose of this study is to share our experience in the management and to add to the existing medical literature regarding the epidemiological patterns of facial dog bite injuries.
Materials and Methods: This is a single-center retrospective observational study conducted at Dr. RML Hospital, New Delhi, from January 2021 to January 2022. A total of 105 patients were included. The wounds were managed according to the recommendations made by the national rabies control program and surgical intervention was performed in the form of primary suturing or flap cover.
Results: Children of age group 0 to 10 years are most commonly affected. Pet dogs are the cause in 61% of cases and 57.1% of bites were provoked. Midface is most commonly affected and modified Lackmann's class 3A and 3B are the most common wounds.
Conclusion: In view of raising incidence of dog bites with pet dogs, the general public needs to be educated regarding the practices to prevent these injuries. Postexposure prophylaxis should be given to all affected individuals irrespective of the vaccination status of the dog. Immediate surgical intervention gives better results.
Between desire and fear: a qualitative interview study exploring the perspectives of carriers of a genetic condition on human genome editing
Authors: Geuverink Wendy , van El Carla , Cornel Martina , Lietaert Peerbolte Bert Jan , Gitsels Janneke , Martin Linda 
Published: August 2023

AbstractHuman genome editing technologies are advancing at a rapid pace, and their potential disruptive implications lead to ethical and societal questions that cannot be addressed by scientists alone. Further consideration of different stakeholders’ views on human genome editing is crucial to translate society’s needs and values into thoughtful regulations and policies. We therefore explored the views of carriers of autosomal dominant disorders on somatic and heritable genome editing (SGE and HGE) and the role of their (secular or religious) worldviews. This group of stakeholders would be most impacted by the eventual clinical application of genome editing technologies and therefore their views must be taken into account. Ten in-depth semi-structured interviews were conducted, and data were analysed using reflexive thematic analysis. We found an overarching theme: ‘Balancing between the desire to prevent serious diseases in individuals through HGE, and the fear of the harmful impact on society and nature’ and three main themes: ‘The benefits of SGE and HGE for individuals’, ‘the societal consequences of using HGE’, and ‘the consequences of interfering with nature through HGE’. Although the lived experiences of the participants varied, they were positive towards the safe use of SGE regardless of the severity of conditions, and most participants were positive towards the use of HGE but only to prevent severe genetic conditions. A few participants were against using HGE in any case, regardless of the severity of a condition, based on their religious beliefs. However, most participants with either religious or secular worldviews reported similar views on HGE, both regarding their desire to prevent serious genetic disorders and their fear of the impact on society and nature if HGE were implemented more widely. Reflecting on HGE involved complex and often ambivalent views. When engaging different stakeholders, space is needed for ambivalence and the weighing of values.
Gate-tunable resistance drops related to local superconducting gaps in thin TaS2 layers on SrTiO3 substrates
Authors: Kosugi M. , Obata R. , Suzuki K. , Kuroyama K. , Du S. , Skinner B. , Kikkawa T. , Yokouchi T. , Shiomi Y. , Maruyama S. , Hirakawa K. , Saitoh E. , Haruyama J. 
Published: August 2023

Strontium titanate [SrTiO3 (STO)], a perovskite oxide with an extremely high gate-tunable dielectric constant (ε) due to quantum paraelectric phases, is attracting considerable attention for yielding various physical phenomena when two-dimensional (2D) layers are integrated. Superconductivity is such a typical phenomenon. However, the influence of the STO substrates on enhancing transition temperatures (Tc) for (atomically) thin 2D flakes attached to them has been rarely investigated. Here, we report gate-tunable and gradual four-terminal resistance drops with critical onset T (TCR) and scanning tunneling spectroscopy (STS) spectra in devices comprising thin TaS2 flakes attached on monolayer hexagonal boron nitride (hBN) spacer/STO substrates. Observation of STS spectra confirms the presence of local superconducting gaps Δ (∼1.5 meV) with transition T (TΔC) three-times higher than previous reports of Tc under absent pressure and strong position dependence of Δ. Depending on Δ on back gate voltages (Vbg) and magnetic fields, there is a strong correlation between TCR and the onset Tc of superconductivity, implying an enhancement of approximately five times compared with the previous highest-onset Tc values without pressure as the applied Vbg increases. The high onset Tc and Δ are discussed based on screening of the long-range Coulomb interaction (CI) due to the high-ε of SrTiO3, while the short-ranged CI remains strong in the 2D limit, causing the superconductivity. Using a monolayer hBN/SrTiO3 substrate with Vbg opens doors to Tc enhancement in thin superconducting layers integrated on it and wide application due to the solid-state high-ε substrates.
Demonstrating the high sensitivity of MoS2 monolayers in direct x-ray detectors
Authors: Taffelli Alberto , Heyl Max , Favaro Matteo , Dirè Sandra , Pancheri Lucio , List-Kratochvil Emil J. W. , Quaranta Alberto , Ligorio Giovanni 
Published: August 2023

Two-dimensional transition metal dichalcogenides (TMDCs) are demonstrated to be appealing semiconductors for optoelectronic applications, thanks to their remarkable properties in the ultraviolet-visible spectral range. Interestingly, TMDCs have not yet been characterized when exposed to x rays, although they would be ideal candidates for optoelectronic applications in this spectral range. They benefit from the high cross section of the constituent heavy atoms, while keeping the absorption very low, due to the ultrathin structure of the film. This encourages the development of photodetectors based on TMDCs for several applications dealing with x rays, such as radioprotection, medical treatments, and diagnosis. Given the atomic thickness of TMDCs, they can be expected to perform well at low dose measurements with minimal perturbation of the radiation beam, which is required for in vivo applications. In this paper, the use of TMDCs as active materials for direct x-ray detection is demonstrated, using a photodetector based on a MoS2 monolayer (1L-MoS2). The detector shows a response to x rays in the range of 101–102 keV, at dose rates as low as fractions of mGy/s. The sensitivity of 1L-MoS2 reaches values in the range of 108–109µC Gy−1 cm−3, overcoming the values reported for most of the organic and inorganic materials. To improve the x-ray photoresponse even further, the 1L-MoS2 was coupled with a polymeric film integrating a scintillator based on terbium-doped gadolinium oxysulfide (Gd2O2S:Tb). The resulting signal was three times larger, enabled by the indirect x ray to visible photoconversion mechanism. This paper might pave the way toward the production of ultrathin real-time dosimeters for in vivo applications.
Uncooled mid-wavelength InAsSb/AlAsSb heterojunction photodetectors
Authors: Kim Yeongho , Alotaibi Saud , Henini Mohamed , Chun Byong Sun , Lee Sang Jun 
Published: August 2023

A mid-wavelength p–B–i–n infrared photodetector constituting ternary alloys of an InAs0.9Sb0.1 absorber and an AlAs0.05Sb0.95 electron barrier was demonstrated to operate at room temperature. The results of high-resolution x-ray diffraction (XRD) analysis indicate the high crystalline quality of the barriode detector structure, grown via molecular beam epitaxy, as supported by the strong XRD peak intensity of InAsSb and its corresponding defect density as low as ∼2.0 × 108 cm−2. The dark current of the barriode detector remained diffusion-limited in the 280–300 K temperature range, and generation–recombination became dominant at 220–260 K owing to the deep-level traps in the depletion region of the absorber and near the lattice-mismatched heterointerface of AlAsSb/InAsSb. Two distinct shallow traps in the InAsSb absorber were identified through Laplace deep-level transient spectroscopy with the activation energies of Et1 = 20 meV and Et2 = 46 meV. The Et1 trap is associated with the hole localization states induced by the alloy disorder of InAsSb, whereas the Et2 trap originated from a point defect of In vacancies in InAsSb. At 300 K, the barriode detector exhibited a 90% cutoff wavelength of 5.0 μm, a peak current responsivity of 0.02 A/W, and a dark current density of 1.9 × 10−3 A/cm2 under a bias voltage of −0.3 V, providing a high specific detectivity of 8.2 × 108 cm Hz1/2/W.
Probing the strength of light–matter interaction in semiconductor microcavities by using resonant-mode shifts in temperature-dependent photoluminescence spectra
Authors: Wu Sheng-Chan , Yang Chung-Xian , Huang Jer-Shing , Chang Yia-Chung , Chien Ching-Hang , Hsu Hsu-Cheng 
Published: August 2023

The Rabi-splitting energy represents the strength of light–matter interaction. This quantity is a good benchmark for evaluating the performance of light-modulation devices. Herein, we adopt ZnO microrods as microcavities for whispering gallery modes and propose a convenient method for estimating the light–matter coupling strength based on the shifts of resonant modes in temperature-dependent photoluminescence spectra from 295 to 77 K. Both temperature-dependent index dispersion and Rabi splitting can be extracted. Additionally, the Rabi-splitting energy of bulk ZnO at 0 K is estimated to be about 289 meV.
Metaphors as tools for understanding in science communication among experts and to the public
Authors: Smedinga Marthe , Cienki Alan , de Regt Henk W. 
Published: August 2023

Abstract
Science communication is highly important in present-day society. But mere factual information transfer does not suffice for enhancing public understanding of scientific results, theories, and concepts. In this paper we compare science communication among experts with communication from experts to laypeople, to better understand the role of metaphors in constructing understanding of abstract scientific concepts. As a case study, we analyze specialist and non-specialist scientific articles on epigenetics, the study of heritable changes in gene expression not altering DNA sequence. The results of our analysis show that there is no substantial difference between the two types of articles in frequency of metaphors and in their content. However, the function of the metaphors is different: the figurative aspect of metaphors is employed for public understanding but plays no role in specialist scientific articles. We outline the implications of these results for current philosophical debates on scientific understanding and public understanding of science: (1) metaphors are tools for rendering theoretical concepts intelligible, for both expert and lay audiences; (2) expert and public understanding differ in degree rather than in kind; (3) conveying understanding crucially involves skills: metaphors in this context do not so much add knowledge as enhance relevant conceptual reasoning abilities.
Reconfigurable spatially-periodic umbilical defects in nematic liquid crystals enabled by self-organization
Authors: Sasaki Yuji , Araoka Fumito , Orihara Hiroshi 
Published: August 2023

Abstract
Spontaneous formation of ordered structures is observed in many physical systems. Soft materials such as colloids, polymers, and liquid crystals (LCs) are stimuli-responsive and often form various functional self-organized structures that are interesting not only fundamentally but also regarding applications. Nematic LCs (NLCs) consisting of elongated molecules are characterized by anisotropic molecular orientations that are strongly affected by external fields. In particular, the combination of an applied electric field and surface boundary conditions is commonly used for controlling stable configurations and plays a fundamental role in LC devices. Currently, the standard approach to fabricating complex molecular orientations is to use tailored surfaces that mostly rely on top-down lithographic techniques, with relatively few examples of bottom-up systems that produce patterned structures. Moreover, previously known systems such as electroconvection are quite dynamic and not sufficiently controllable, even though they exhibit a variety of patterns. Therefore, exploring the physical mechanism for the formation of a spontaneous pattern could be important in exploiting the further functional properties of NLCs. Here, we briefly review a unique type of self-organization in NLCs induced by an electric field, where the crucial effects of the polymer layer between the NLC and the electrodes lead to the formation of a two-dimensional periodic structure in the sample cell instead of the standard reorientation process. As well as experimental demonstration of the phenomenon, a descriptive theoretical framework is discussed, as are perspectives for optical applications.
Existence of nodal-arc and its evolution into Weyl-nodes in the presence of spin-orbit coupling in TaAs & TaP
Authors: Pandey Vivek , Pandey Sudhir K 
Published: August 2023

Abstract
In this work, we report the existence of nodal-arc, which acts as the building block of all the nodal-rings in TaAs & TaP. This nodal-arc is found to be capable of generating all the nodal-rings in these materials upon the application of space-group symmetry operations including time-reversal symmetry. The arcs are obtained to be dispersive with the energy spread of ∼109 (∼204) meV in TaAs (TaP). Also, the orbitals leading to bands-inversion and thus the formation of nodal-arcs are found to be Ta-5d & As-4p (P-3p) in TaAs (TaP). The area of nodal-rings is found to be highly sensitive to the change in hybridization-strength, where the increase in hybridization-strength leads to the decrease in the area of nodal-rings. In the presence of spin–orbit coupling (SOC), all the points on these arcs get gaped-up and two pairs of Weyl-nodes are found to evolve from them. Out of the two pair, one is found to be situated close to the joining point of the two arcs forming a ring. This causes the evolution of each nodal-ring into three pairs of Weyl-nodes. The coordinates of these Weyl-nodes are found to be robust to the increase in SOC-strength from ∼0.7–3.5 eV. All the results are obtained at the first-principle level. This work provides a clear picture of the existence of nodal-arc due to accidental degeneracy and its evolution into Weyl-nodes under the effect of SOC.
Unsteady Ohmic dissipative flow of ZnO-SAE50 nanofluid past a permeable shrinking cylinder
Authors: Haider Ghulam , Ahmed Naveed 
Published: August 2023

Abstract
The laminar boundary layer flow of a Zinc Oxide-Society of Automotive Engineers 50 alias nano-lubricant (

ZnO
−
SAE
50

) past a permeable shrinking cylinder is investigated. The flow is unsteady, incompressible, and Ohmic dissipative. The present study holds immense significance in different engineering as well as scientific domains. It combines research on nanoparticle effects, unsteady flows, and solid surface interactions. The study claimed that the use of

ZnO
−
SAE
50

nanofluid in the unsteady flow past a permeable shrinking cylinder led to significant heat transfer enhancement. The acquired results from the study would be fruitful in the fields of thermal engineering and heat transfer. The findings of the study can aid in optimizing cooling systems, heat exchangers, and energy-efficient designs. A governing model has been achieved for the flow and heat transfer by using conservation laws related to mass, momentum, and energy. Governing system of partial differential equations is solved to a nonlinear system of ordinary differential equations by using similarity transformation, which is later on solved with the help of the Shooting method and RK-Fehlberg duos. Plots are shown for both velocity and temperature profiles, to display the impacts of involved dimensionless parameters. Additionally, graphs for Nusselt Number have also been represented which shows the local rate of heat transfer. It is examined that the Ohmic dissipation as well as the volumetric ratio of the nanoparticles greatly influence the overall thermal performance of the system.
A machine learning-based approach for RF transfer function modeling of active implantable medical electrodes at 3T MRI
Authors: Yao Aiping , Ma Mingjuan , Shi Hexuan 
Published: August 2023

Abstract

Objective. The objective of this work is to propose a machine learning-based approach to rapidly and efficiently model the radiofrequency (RF) transfer function of active implantable medical (AIM) electrodes, and to overcome the limitations and drawbacks of traditional measurement methods when applied to heterogeneous tissue environments. Approach. AIM electrodes with different geometries and proximate tissue distributions were considered, and their RF transfer functions were modeled numerically. Machine learning algorithms were developed and trained with the simulated transfer function datasets for homogeneous and heterogeneous tissue distributions. The performance of the method was analyzed statistically and validated experimentally and numerically. A comprehensive uncertainty analysis was performed and uncertainty budgets were derived. Main results. The proposed method is able to predict the RF transfer function of AIM electrodes under different tissue distributions, with mean correlation coefficients r of 0.99 and 0.98 for homogeneous and heterogeneous environments, respectively. The results were successfully validated by experimental measurements (e.g. the uncertainty of less than 0.9 dB) and numerical simulation (e.g. transfer function uncertainty <1.6 dB and power deposition uncertainty <1.9 dB). Up to 1.3 dB in vivo power deposition underestimation was observed near generic pacemakers when using a simplified homogeneous tissue model. Significance. Provide an efficient alternative of transfer function modeling, which allows a more realistic tissue distribution and the potential underestimation of in vivo RF-induced power deposition near the AIM electrode can be reduced.