bluuebunny/crossref_metadata_2025_split huggingface dataset:
INVESTIGATION OF PHYSICAL ACTIVITY, SLEEP QUALITY, ANXIETY AND DEPRESSION LEVELS AMONG EXERCISER AND NON-EXERCISER ADULTS IN THE COVID-19 PANDEMIC
Authors: ZENGİN ALPÖZGEN Ayşe , EMİRZA Çiğdem , GÜRDAL KARAKELLE Saliha , ŞENEL Aybike , YASACI Zeynal , ERTAN HARPUTLU Özge 
Published: August 2023

Purpose: To assess physical activity (PA), perceived exercise benefits, perceived sleep quality, anxiety and depression levels of adults who exercised and did not exercise during the pandemic.
Methods: 1226 voluntary participants who lived in the community (age range 18-55 years) were included in this cross-sectional study. Demographic information was recorded, and exercise motivators and barriers were evaluated through questions prepared by the researchers. PA levels [International Physical Activity Questionnaire-Short Form (IPAQ-SF)], perception about the benefits of exercise [Exercise Benefits and Barriers Scale-Benefits Subscale (EBBS-BS)], sleep quality [Pittsburgh Sleep Quality Index (PSQI)], and anxiety and depression levels [Hospital Anxiety and Depression Scale (HADS)] were assessed.
Results: There were statistically significant differences in scores of IPAQ-SF, PSQI, EBBS-BS, and HADS between those who did and did not exercise (p
TÜRKİYE’DEKİ FİZYOTERAPİSTLERİN KARDİYOPULMONER RESÜSİTASYON BİLGİ DÜZEYLERİNİN DEĞERLENDİRİLMESİ
Authors: KILIÇ Rabia Tuğba , MEŞE-BURAN Melike , YOSMAOĞLU Hayri Baran 
Published: August 2023

Amaç: Bu çalışmanın amacı, Türkiye’de çalışmakta olan fizyoterapistlerin Kardiyopulmoner Resüsitasyon (KPR) hakkındaki bilgi düzeylerini değerlendirmekti.
Yöntem: Ağustos-Ekim 2021 tarihleri arasında yürütülen kesitsel bir araştırmadır. Çalışmaya katılmayı kabul eden 164’ü (%59,63) erkek, 111’i (%40,37) kadın olmak üzere toplam 275 fizyoterapiste online anket formu gönderilerek veriler toplandı. KPR bilgi düzeyini değerlendirmek amacıyla 2010 Amerikan Kalp Cemiyeti (AHA)-ERC KPR kılavuzu rehber alınarak hazırlanan anket toplam 26 sorudan oluşmakta ve kendi kendine uygulanmaktadır. Anketin ilk bölümünde kişisel bilgileri içeren 5 soru (yaş, cinsiyet, çalıştıkları kurum, çalışma süresi vb.); ikinci bölümde KPR eğitimi ve değerinin algılanmasına yönelik 12 soru , üçüncü bölümde ise KPR ile ilgili bilgi düzeylerini ölçmeyi hedefleyen 10 soru yer almaktadır. KPR bilgi puanında 0-5 puan aralığı düşük, 6-10 puan aralığı ise yüksek olarak değerlendirildi.
Sonuçlar: En çok çalışılan kurum hastane (%41,50) ve çalışma alanı ise kas-iskelet sistemi (%37,80) idi. Herhangi bir yerde kardiyak arrest (KA) vakası ile karşılaşanların oranı %28,40 iken çalışma ortamında bu oran %20,70 idi. Katılımcıların çoğu (%67,30) KPR eğitimi almıştı ancak eğitim alanlar KPR uygulama konusunda %59,50’si eğitimi, %71,90’u da kendisini yetersiz buldu. Çalışma alanı, yaş, cinsiyet ve deneyim yılına göre KPR sertifikasına sahip olma durumu ilişkili değildi(p>0,05).Hastanede çalışanların KPR sertifikası sahip olma oranı üniversitede çalışanlara göre daha yüksekti(p=0,014).Teorik KPR bilgi puanı ortalaması 5±0,12 idi, bu sonuç KPR bilgi düzeylerinin düşük olduğunu gösterdi. KPR bilgi puanı; KPR eğitimi alanlarda almayanlara göre, KPR uygulamasında kendini yeterli görenlerde de yeterli görmeyenlere göre daha yüksekti(p=0,001).
Tartışma: Sonuçlarımız fizyoterapistlerin çoğunluğunun, KPR sertifikasının olduğunu fakat KPR sertifikası olanların çoğunluğunun da KPR bilgi düzeylerinin yetersiz olduğunu ve kendilerini bu konuda yetersiz hissettiklerini göstermiştir. KPR uygulamasını daha iyi değerlendirmek isteyen gelecekteki araştırmalar fizyoterapistlerin gerçek KPR yeterliliğini teorik bir değerlendirmeden ziyade uygulamalı yöntemlerle değerlendirmelidir.
THE RELATIONSHIP BETWEEN BURNOUT LEVEL AND HOPELESSNESS, PERCEIVED SOCIAL SUPPORT AND MENTAL WELL-BEING IN PHYSIOTHERAPY AND REHABILITATION SENIOR UNDERGRADUATE STUDENTS
Authors: BİRİNCİ Tansu , BAŞTÜRK Pınar 
Published: August 2023

Purpose: This study aimed to investigate the relationship between burnout level and hopelessness, perceived social support, and mental well-being among physiotherapy and rehabilitation senior undergraduate students.
Methods: Three hundred sixty-nine physiotherapy and rehabilitation senior undergraduate students (195 female, mean age: 22.81±3.72 years) were included in the present study. Data were collected using the online survey with a combination of the Maslach Burnout Inventory-Student Survey (MBI-SS), Beck Hopelessness Scale (BHS), Multidimensional Scale of Perceived Social Support (MSPSS), and Warwick-Edinburgh Mental Well-Being Scale (WEMWBS).
Results: There are no gender differences in burnout level and hopelessness level, perceived social support, mental well-being, and sociodemographic characteristics (p>0.05). There were significant relationships between the emotional exhaustion and cynicism subscales of MBI-SS and BHS, MSPSS, and WEMWBS (p
Water-preserved coal mining in water-shortage mining areas: a case study in the Yonglong mining area of China
Authors: Shi Xiuchang , Lyu Guangluo 
Published: August 2023

Abstract

Water-preserved coal mining (WPCM) in water-shortage mining areas is an important aspect of water resources management. This paper aimed at the protection of Cretaceous groundwater resources during the high-intensity mining in the Yonglong mining area, China, and carried out basic theory and practical application of WPCM. The hydrogeological structure and engineering geological characteristics were investigated on-site. On-site detection and numerical simulation were used to study the dynamic evolution laws of overburden failure and water-conducting fractured zone (WCFZ), and the seepage laws of mining-induced overburden were analyzed by the rock triaxial seepage test. The results showed that it was feasible to carry out WPCM in the Yonglong mining area. From the view of reducing the height of WCFZ and preventing water hazards, the technical measures for WPCM were proposed. The research results can provide a theoretical basis and technical approach for WPCM in the water-shortage mining areas.
Mbo’ehára rembiapo para além do alinhamento à lógica do capital
Authors: Siqueira Adriana Oliveira dos Santos , Nunes da Silva José Moisés 
Published: August 2023

O objetivo do artigo é analisar a trajetória da formação de professores (mbo’ehára rembiapo) no Brasil, a partir da década de 1990, e refletir sobre o devir de uma formação ampla, no sentido da ruptura com o alinhamento à lógica do capital. A pesquisa tem abordagem qualitativa, mediada pelas pesquisas bibliográfica e documental, e a dialética como referencial de análise. Discutem-se a lógica pragmatista, a perspectiva progressista e o retrocesso na mbo’ehára rembiapo. Os resultados apontam que as diretrizes curriculares nacionais para a mbo’ehára rembiapo foram um avanço à identidade dos cursos de licenciatura; e que é possível uma outra formação, fundada na formação humana integral, para além do alinhamento à lógica do capital.
Traumatic Chylothorax due to Cervical Stab Wound: A Case Report
Authors: Tebar Gabriela Karabachian , de Lima Silva Rafael , Gaspar Thiago , Hernandes Lopes Vitor , de Castro Vinicius Vertematti , da Silva Rodrigues Jose Mauro , Ribeiro Junior Marcelo A. F. 
Published: September 2023

Background:
Chylothorax corresponds to the incidence of chyle in the pleural space; it was described for the first time in 1633. Its most common cause is associated with iatrogenic injuries to the thoracic duct; 80% of them take place during surgeries, such as pneumonectomy or esophagectomy.

Case presentation:
A case of an unusual cervical stab wound complication in a 23-year-old man who presented a late large volume chylothorax has been presented and discussed in this paper, as well as its management.

Discussion:
The presented case demonstrates a rare complication after a cervical stab wound. The management of chylothorax can involve non-operative management, non-operative intervention, or operative management depending on the symptoms and duration. Usually, surgical interventions are required after two weeks of clinical treatment. The differential diagnosis in a post-trauma acute onset ventilatory manifestation is mandatory to rule out pulmonary embolism.

Conclusion:
Traumatic chylothorax is a rare event; however, its morbidity and mortality rates can be catastrophic when it is not diagnosed early and when the treatment is not established based on a proper flowchart. Thus, dietary and drug-based clinical measures, interventional radiology, videothoracoscopy, and thoracotomy for thoracic duct ligation are valid therapeutic options for the proper management of these cases.
Chemical Composition, In vitro and In silico Evaluation of Essential Oil
from Ocimum tenuiflorum and Coriandrum sativum Linn for Lung Cancer
Authors: Singh Bhim , Prajapati Kumari Sunita , Kumar Amit , Patel Shivam , Kumar Shashank , Jaitak Vikas 
Published: September 2023

Background:
Medicinal plants play an essential role in everyday life; plants highly
contain therapeutic phytoconstituents commonly used to treat various diseases. This paper discusses
the Chemical composition, In vitro antiproliferative activity and In silico study of essential
oil extracted from Ocimum tenuiflorum (family Lamiaceae) and Coriandrum sativum (family
Apiaceae).

Objective:
In present study GC-MS was used to identify the chemical constituents from O. tenuiflorum
and C. sativum. In vitro antiproliferative activity was performed on A549 cancer cell lines.
In silico study was performed by Schrodinger’s maestro software to identify chemical constituents
in both plants as potential EGFR inhibitors for the treatment of lung cancer

Methods:
The essential oil was extracted by hydro distillation from aerial parts of O. tenuiflorum
and C. sativum. The volatile oil sample was analyzed by (GC-MS) Gas Chromatography-
Mass Spectrometry. Different chemical constituents were identified based on the retention index
and compared with the NIST library. The oil samples from O. tenuiflorum and C. sativum was
also evaluated for antiproliferative activity against human lung cancer A549 cell lines. In silico
study was performed by Schrodinger maestro software against EGFR (PDB ID 5HG8).

Resuls:
O. tenuiflorum essential oil contains Eugenol (42.90%), 2-β-Elemene (25.98%), β-
Caryophyllene (19.12%) are the major constituents. On the other side, C. sativum contains nnonadecanol-
1 (16.37%), decanal (12.37%), dodecanal (12.27%), 2-Dodecanal (9.67%), Phytol
(8.81%) as the major constituents. Both the oils have shown in vitro antiproliferative activity
against human lung cancer cell lines A549 having IC50 values of 38.281 μg/ml (O. tenuiflorum)
and 74.536 μg/ml (C. sativum). Molecular interactions of constituents hydro distilled from two
oils was analysed by schrodinger maestro software against EGFR (PDB ID 5HG8).

Conclusion:
The oil sample extracted from O. tenuiflorum showed more antiproliferative activity
than C. sativum. In silico study showed that two chemical constituents, namely di-isobutyl
phthalate (-7.542 kcal/mol) and dibutyl phthalate (-7.181 kcal/mol) from O. tenuiflorum and one
diethyl phthalate (-7.224 kcal/mol) from C. sativum having more docking score than standard
Osimertinib which indicates the effectiveness of oils for lung cancer.
QSAR Research of Novel Tetrandrine Derivatives against Human Hepatocellular
Carcinoma
Authors: Wang Meng , Qiu Bin , Wang Wenhui , Li Xiang , Huo Huixia 
Published: September 2023

Background:
The new tetrandrine derivative is an anti-human liver cancer cell inhibitor which can be used
to design and develop anti-human-liver-cancer drugs.

Objective:
A quantitative structure-activity relationship (QSAR) model was established to predict the physical properties
of new tetrandrine derivatives using their chemical structures.

Methods:
The best descriptors were selected through CODESSA software to build a multiple linear regression model.
Then, gene expression programming (GEP) was used to establish a nonlinear quantitative QSAR model with descriptors
to predict the activity of a series of novel tetrandrine chemotherapy drugs. The best active compound 31 was
subjected to molecular docking experiments through SYBYL software with a small fragment of the protein receptor
(PDB ID:2J6M).

Results:
Four descriptors were selected to build a multiple linear regression model with correlation coefficients R2,
R2CV and S2 with the values of 0.8352, 0.7806 and 0.0119, respectively. The training and test sets with a correlation
coefficient of 0.85 and 0.83 were obtained via an automatic problem-solving program (APS) using the four selected
operators as parameters, with a mean error of 1.49 and 1.08. Compound 31 had a good docking ability with an overall
score of 5.8892, a collision rate of -2.8004 and an extreme value of 0.9836.

Conclusion:
The computer-constructed drug molecular model reveals the factors affecting the activity of human hepatocellular
carcinoma cells, which provides directions and guidance for the development of highly effective anti-humanhepatocellular-
carcinoma drugs in the future.
An Overview of the Therapeutic Efficacy of (-)-Epicatechin in the
Management of Diabetes Mellitus
Authors: Dash Jyoshna R , Pattnaik Gurudutta , Ghosh Goutam , Rath Goutam , Kar Biswakanth 
Published: September 2023

Background and Aims:
Diabetes mellitus is a chronic metabolic disorder affecting global
public health. Since ancient, natural-based compounds are widely used for multiple indications of diabetes.

Methods:
The natural-based (-)-Epicatechin has enormous biological functions including antioxidant and
anti-inflammatory activities. This review mainly focuses on the importance of epicatechin in the control
of pathogenesis involved in diabetic mellitus. Additionally, its possible mechanisms involved in beta cell
regeneration, insulin secretion, and insulin sensitivity.

Results:
The present article explored the potential antioxidant, mitochondrial protection, and antiinflammatory
properties using the preclinical and clinical model, and also established the role of (-)-
Epicatechin in the mitigation of diabetic-associated complications.
Lastly, the article mentioned the limitation of the use of epicatechin.

Conclusion:
This will provide new insight to budding scientists for the development of novel bioactivebased
pharmaceuticals for the management of diabetic mellitus.
Nanoemulsion of Ethanolic Extract of Centella asiatica (NanoSECA)
Ameliorates Learning and Memory Performance by Enhancing
Cholinergic Activities, Increasing Antioxidative Levels, and Attenuating
Oxidative Stress Markers in Adult Rats
Authors: Jusril Nor Atiqah , Mukhtar Shahida Muhammad , Abu Bakar Syahrul Imran , Md Saad Wan Mazlina , Wen Ng Kwok , Adenan Mohd Ilham 
Published: September 2023

Background:
Centella asiatica (C. asiatica) has long been traditionally used as a memory
enhancer. Nanoemulsion of ethanolic extract C. asiatica (NanoSECA) has been developed to improve
brain functions. However, the effect of NanoSECA on enhancing memory and cognitive functions remains
unexplored.

Objectives:
This research aimed to investigate the potential of NanoSECA on cognitive tasks and
memory enhancement pathways in a normal adult rat model.

Methods:
Thirty male Sprague Dawley rats (7-8 weeks old) were randomly subjected to five groups
(n=six per group). Treatment groups were supplemented with NanoSECA and ethanolic extract of C.
asiatica (SECA) for 28 days by oral gavages. Different brain sections were isolated, homogenized, and
tested for acetylcholinesterase, antioxidants (glutathione and malondialdehyde), and anti-inflammatory
agents (nitric oxide, tumour necrosis factor-α, and prostaglandin E2).

Results:
NanoSECA supplementation markedly enhanced the acetylcholine, glutathione levels and reduced
a distinct diminution in plasma activities of acetylcholinesterase, malondialdehyde, nitric oxide,
prostaglandin E, and tumor necrosis factor-α levels.

Conclusion:
NanoSECA can be used as a memory enhancer through enhanced cholinergic activity, increased
antioxidant level, and reduced oxidative stress.
Ionic Conductivity, Dielectric, and Structural Insights of Deep Eutectic
Solvent-based Polymer Electrolyte: A Review
Authors: Shaharuddin N.A.A. , Abidin S.Z.Z. 
Published: September 2023

Abstract:
The exponential concern about environmental concerns has heavily driven the development of green technology. In light of these needs, Deep Eutectic Solvent (DES) emerged as a green solvent and additive due to its minimal toxicity and volatility, biodegradability, biocompatibility, simplicity of synthesis, high yields and purity, and the availability of its precursors. This review is intended to summarise and discuss polymer electrolytes based on DES for better insight into the potential of replacing conventional organic solvents or ionic liquids for energy storage applications in the aspect of their electrical and structural properties. Therefore, an examination of dielectric studies is conducted as they hold significance in establishing a correlation between the rise in ionic conductivity and the augmentation of freely movable ions, thereby highlighting the importance of investigating the dielectric properties of an electrolyte. Besides, XRD and morphological studies in this work can show how ionic conductivities can influence the size of pores in DES-based polymer electrolytes.
Facile Synthesis of Dysprosium Oxide/Bismuth Oxide Nanocomposite Electrode Materials with Good Electrocatalytic Performance
Authors: Sun Zizhan , Wang Xiaoyu , Cong Qianmin , Feng Chenxu , Zhang Xu , Cai Zhengyu , Zhang Yong , Pei Lizhai 
Published: September 2023

Background:
Benzoic acid is widely applied in the food field, including beverages
as the antimicrobial preservative due to its strong inhabitation role to bacteria
and yeasts. However, excessive intake of benzoic acid can easily cause abdominal pain
and diarrhea and can even result in metabolic diseases. Hence, it is important to seek
simple, accurate and sensitive strategies to detect low-trace benzoic acid.

Objective:
The aim of this study is to synthesize dysprosium oxide/bismuth oxide nanocomposites
using dysprosium sulphate and sodium bismuthate as the raw materials and
research the electrochemical sensing properties for the detection of benzoic acid.

Methods:
Dysprosium oxide/bismuth oxide nanocomposites were synthesized by a facile
hydrothermal route. The dysprosium oxide/bismuth oxide nanocomposites were
characterized by X-ray diffraction, electron microscopy, X-ray photoelectron spectroscopy
and electrochemical impedance spectroscopy.

Results:
The dysprosium oxide/bismuth oxide nanocomposites are composed of nearly
circular-shaped particles with polycrystalline cubic Dy2O3 and triclinic Bi2O3 phases.
The size of the nearly circular-shaped particles is about 50 to 200 nm. The electrons are
easier to transfer by the dysprosium oxide/bismuth oxide nanocomposite-modified electrode
than the bare electrode. A pair of quasi-reversible cyclic voltammetry (CV) peaks
located at -0.155 V and -0.582 V exist in the CV curve of 0.1 M KCl buffer solution
containing 2 mM benzoic acid. The nanocomposite-modified electrode shows a linear
detection range and detection limit of 0.001-2 mM and 0.18 μM, respectively, for benzoic
acid detection.

Conclusion:
The dysprosium oxide/bismuth oxide nanocomposite-modified electrode
reveals superior electro-catalytic activity towards benzoic acid.
Visualizing Wearable Medical Device Research Trends: A Co-occurrence Network-Based Bibliometric Analysis
Authors: Misra Bitan , Roy Nilanjana Dutta , Dey Nilanjan , Sherratt Robert Simon 
Published: September 2023

Background. One of the most crucial aspects of someone’s life is health. Therefore, individuals should be conscious about keeping themselves healthy by regular monitoring their health, which can be done with the help of modern medical technologies. Wearable medical devices using wearable sensors are the popular names of emerging technologies in the modern healthcare domain.
Aim. This work presents the results of a systematic investigation of extensive research that has occurred for the last two decades in these research streams to provide a comprehensive mapping and temporal distribution of wireless medical device research.
Methods. This study presents a relationship between the bibliographic items, their quality, and the quantity representing the most effective research topics on wearable medical devices. The analysis is performed using two useful parameters, namely a bibliometric network and a co-occurrence matrix. Data collection, data standardization, data mapping, and result analysis are the steps involved in the bibliometric analysis technique. In this study, VOSviewer software for bibliometric analysis is applied to the Scopus database.
Results. By analysing bibliometric indicators from the Scopus database and using VOSviewer, we represent their distribution in countries, institutions, top researchers, and top journals. Furthermore, we analyse the co-citation of cited authors and the co-occurrence of keywords. The outcomes of the clustering and keyword analysis indicate that the research domain primarily focuses on the Internet of Things, machine learning, wearable sensors, mobile health, electrocardiogram, etc.
Conclusions. Statistical investigation in association with the visual exploration presented in this article provides more substantial information than either of them used separately. In the future, this article can illuminate researchers and practitioners to develop a different theory to look at the factors that influence predictability in the research domain of wearable medical devices.