bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dutch normative data of the sexual distress scale and the body image scale
Authors: Huberts Anouk S. , Peeters Noëlle J. M. C. Vrancken , Kaplan Z. L. Rana , van Linschoten Reinier C. A. , Pastoor H. , van der Woude C. Janneke , Koppert Linetta B. 
Published: May 2023

AbstractPurposeSexual health is an important contributing factor for health-related quality of life, but research in this domain is scarce. Moreover, normative data are needed to interpret patient-reported outcome measures on sexual health. The aim of this study was to collect and describe normative scores of the Female Sexual Distress Scale (FSDS) and the Body Image Scale (BIS) from the Dutch population and assess the effect of important demographic and clinical variables on the outcome. As the FSDS is also validated in men, we refer to it as SDS.MethodDutch respondents completed the SDS and BIS between May and August 2022. Sexual distress was defined as a SDS score > 15. Descriptive statistics were calculated to present normative data per age group per gender after post-stratification weighting was applied. Multiple logistic and linear regression analyses were conducted to assess the effect of age, gender, education, relationship status, history of cancer and (psychological) comorbidities on SDS and BIS.ResultsFor the SDS 768 respondents were included with a weighted mean score of 14.41 (SD 10.98). Being female (OR 1.77, 95% CI [1.32; 2.39]), having a low educational level (OR 2.02, CI [1.37; 2.39]) and psychological comorbidities (OR: 4.86, 95% CI [2.17; 10.88]) were associated with sexual distress. For the BIS, 696 respondents were included. Female gender (β: 2.63, 95% CI [2.13; 3.13]), psychological comorbidities (β: 2.45, 95% CI [1.43; 3.47]), higher age (β: −0.07, 95% CI [−0.09; −0.05]), and a high educational level (β:−1.21, CI: −1.79 to −0.64) were associated with the non-disease related questions of the Body Image Scale.ConclusionThis study provides age- and gender-dependent normative values for the SDS and the non-disease related questions of the BIS. Sexual distress and body image are influenced by gender, education level, relationship status and psychological comorbidities. Moreover, age is positively associated with Body Image.
Assessing Sustainable Development of Deep Aquifers
Authors: Dietmaier Annette , Baumann Thomas 
Published: May 2023

AbstractDeep groundwater aquifers are exploited for a variety of purposes. In general, impermeable rock layers protect these aquifers from anthropogenic influences. As such, they are a last resort for groundwater in a pre-industrial state, and a crucial resource in cases of emergency, such as floods contaminating shallow groundwater. The EU Water Framework Directive (WFD) provides the regulatory framework to protect its quality and quantity. Recent monitoring of the hydrochemical state of Upper Jurassic wells in Bavaria and Austria has shown fluctuations that were connected to new exploitation activities and might indicate an unsustainable development of the aquifer. We propose a new workflow in accordance with the WFD which uses clustering algorithms to assess these fluctuations. Our data consists of 5 to 42 hydrochemical analyses per well with yearly sampling intervals spanning up to 30 years. From the cluster analysis we derived thresholds for two corridors: Natural Range Corridor (NC) and Action Corridor (AC). While the NC represents a well-specific natural variation range, the AC hints towards unsustainable development and should trigger a detailed (re)assessment. To show the potential of the new method, the workflow was applied to two wells with different geological characteristics. Distinct fluctuation events were clearly recognized and can be used in the context of an early warning system, such that malign hydrochemical variations can be detected before they become legally problematic to well operators. Our workflow thus provides a novel, robust, and reproducible method to assess the grade of sustainability at which a well is exploited and ensures a good status of a unique and important resource.
Investigating extreme hydrological risk impact on water quality; evidence from Buffalo catchment headwater, Eastern Cape, South Africa
Authors: Owolabi Solomon Temidayo , Belle Johanes A. 
Published: May 2023

Abstract
Evidence from increasing mineralization, micropollutant concentrations, waterborne epidemics, an algal boom, and dissolved organic matter has provided substantial evidence that climate change impacts water quality. While the impact of the extreme hydrological event (EHE) on water quality (WQ) has aroused considerable research interest, research uncertainty has been premised on WQ data scarcity, a short time frame, data non-linearity, data structure, and environmental biases on WQ. This study conceptualized a categorical and periodic correlation using confusion matrices and wavelet coherence for varying standard hydrological drought index (SHDI; 1971–2010) and daily WQ series (1977–2011) of four spatially distinct basins. By condensing the WQ variables using chemometric analyses, confusion matrices were assessed by cascading the SHDI series into 2-, 3-, and 5-phase scenarios. 2-phase revealed an overall accuracy (0.43–0.73), sensitivity analysis (0.52–1.00), and Kappa coefficient (− 0.13 to 0.14), which declines substantially with the phase increase, suggesting the disruptive impact of EHE on WQ. Wavelet coherence depicted the substantial ($${R}_{n}^{2}\left(u,s\right)\ge 0.5$$

R

n

2

u
,
s

≥
0.5

) mid- and long-term (8–32 days; 6–128 days) co-movement of streamflow over WQ, confirming the varying sensitivity of WQ variables. Land use/land cover mapping and the Gibbs diagram corroborate the eventful WQ evolution by EHE and their spatial variability concerning landscape transformation. Overall, the study deduced that hydrologic extreme triggers substantial WQ disruption with dissimilar WQ sensitivity. Consequently, suitable chemometric indicators of EHE impacts such as WQ index, nitrate-nitrogen, and Larson index at designated landscapes were identified for extreme chemodynamics impact assessment. This study proffers a recommendation for monitoring and managing the impact of climate change, floods, and drought on water quality.
Geographical Differences of Risk of Asthma and Allergic Rhinitis according to Urban/Rural Area: a Systematic Review and Meta-analysis of Cohort Studies
Authors: Song Mincheol , Hwang Seohyeon , Son Eunjeong , Yeo Hye Ju , Cho Woo Hyun , Kim Tae Woo , Kim Kihun , Lee Dongjun , Kim Yun Hak 
Published: May 2023

AbstractSeveral studies have demonstrated an association between the risk asthma/allergic rhinitis and the environment. However, to date, no systematic review or meta-analysis has investigated these factors. We conducted a systematic review and meta-analysis to assess the association between urban/rural living and the risk of asthma and allergic rhinitis. We searched the Embase and Medline databases for relevant articles and included only cohort studies to observe the effects of time-lapse geographical differences.Papers containing information on rural/urban residence and respiratory allergic diseases were eligible for inclusion. We calculated the relative risk (RR) and 95% confidence interval (CI) using a 2 × 2 contingency table and used random effects to pool data. Our database search yielded 8388 records, of which 14 studies involving 50,100,913 participants were finally included. The risk of asthma was higher in urban areas compared to rural areas (RR, 1.27; 95% CI, 1.12–1.44,p< 0.001), but not for the risk of allergic rhinitis (RR, 1.17; 95% CI, 0.87–1.59,p= 0.30). The risk of asthma in urban areas compared to rural areas was higher in the 0–6 years and 0–18 years age groups, with RRs of 1.21 (95% CI, 1.01–1.46,p= 0.04) and 1.35 (95% CI, 1.12–1.63,p= 0.002), respectively. However, there was no significant difference in the risk of asthma between urban and rural areas for children aged 0–2 years, with a RR of 3.10 (95% CI, 0.44–21.56,p= 0.25). Our study provides epidemiological evidence for an association between allergic respiratory diseases, especially asthma, and urban/rural living. Future research should focus on identifying the factors associated with asthma in children living in urban areas. The review was registered in PROSPERO (CRD42021249578).
Estimating the future clinical and economic benefits of improving osteoporosis diagnosis and treatment among postmenopausal women across eight European countries
Authors: Yeh Eric J. , Gitlin Matthew , Sorio Francesc , McCloskey Eugene 
Published: May 2023

Abstract
Summary
A
population-level, cross-sectional model was developed to estimate the clinical and economic burden of osteoporosis among women (≥ 70 years) across eight European countries. Results demonstrated that interventions aimed at improving fracture risk assessment and adherence would save 15.2% of annual costs in 2040.

Purpose
Osteoporosis is associated with significant clinical and economic burden, expected to further increase with an ageing population. This modelling analysis assessed clinical and economic outcomes under different hypothetical disease management interventions to reduce this burden.

Methods
A population-level, cross-sectional cohort model was developed to estimate numbers of incident fractures and direct costs of care among women (≥ 70 years) in eight European countries under different hypothetical interventions: (1) an improvement in the risk assessment rate, (2) an improvement in the treatment adherence rate and (3) a combination of interventions 1 and 2. A 50% improvement from the status quo, based on existing disease management patterns, was evaluated in the main analysis; scenario analyses evaluated improvement of either 10 or 100%.

Results
Based on existing disease management patterns, a 44% increase in the annual number of fractures and costs was predicted from 2020 to 2040: from 1.2 million fractures and €12.8 billion in 2020 to 1.8 million fractures and €18.4 billion in 2040. Intervention 3 provided the greatest fracture reduction and cost savings (a decrease of 17.9% and 15.2% in fractures and cost, respectively) in 2040 compared with intervention 1 (decreases of 8.7% and 7.0% in fractures and cost, respectively) and intervention 2 (10.0% and 8.8% reductions in fracture and cost, respectively). Scenario analyses showed similar patterns.

Conclusion
These analyses suggest that interventions which improve fracture risk assessment and adherence to treatments would relieve the burden of osteoporosis, and that a combination strategy would achieve greatest benefits.
Mechanistic Approach on the Pulmonary Oxido-Inflammatory Stress Induced by Cobalt Ferrite Nanoparticles in Rats
Authors: Hassanen Eman I. , Abdelrahman Rehab E. , Aboul-Ella Hassan , Ibrahim Marwa A. , El-Dek Samaa , Shaalan Mohamed 
Published: May 2023

AbstractCobalt ferrite nanoparticles (CFN) are employed in data storage, imaging, medication administration, and catalysis due to their superparamagnetic characteristics. The widespread use of CFN led to significantly increased exposure to people and the environment to these nanoparticles. Until now, there is not any published paper describing the adverse effect of repeated oral intake of this nanoformulation on rats’ lungs. So, the current research aims to elucidate the pulmonary toxicity prompted by different concentrations of CFN in rats as well as to explore the mechanistic way of such toxicity. We used 28 rats that were divided equally into 4 groups. The control group received normal saline, and the experimental groups received CFN at dosage levels 0.05, 0.5, and 5 mg/kg bwt. Our findings revealed that CFN enhanced dose-dependent oxidative stress manifested by raising in the MDA levels and declining in the GSH content. The histopathological examination revealed interstitial pulmonary inflammation along with bronchial and alveolar damage in both 0.5 and 5 mg CFN given groups. All these lesions were confirmed by the immunohistochemical staining that demonstrated strong iNOS and Cox-2 protein expression. There was also a significant upregulation of TNFα, Cox-2, and IL-1β genes with downregulation of IL-10 and TGF-β genes. Additionally, the group receiving 0.05 mg CFN did not exhibit any considerable toxicity in all measurable parameters. We concluded that the daily oral intake of either 0.5 or 5 mg CFN, but not 0.05 mg, could induce pulmonary toxicity via NPs and/or its leached components (cobalt and iron)-mediated oxido-inflammatory stress. Our findings may help to clarify the mechanisms of pulmonary toxicity generated by these nanoparticles through outlining the standards for risk assessment in rats as a human model.
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway
Authors: Chen Jie , Zhu Tong , Yu Dongyu , Yan Bing , Zhang Yuxiang , Jin Jungong , Yang Zhuojin , Zhang Bao , Hao Xiuli , Chen Zhennan , Yan Chunxia , Yu Jun 
Published: May 2023

Abstract
Traumatic brain injury (TBI) is a universal leading cause of long-term neurological disability and causes a huge burden to an ever-growing population. Moderate intensity of treadmill exercise has been recognized as an efficient intervention to combat TBI-induced motor and cognitive disorders, yet the underlying mechanism is still unclear. Ferroptosis is known to be highly implicated in TBI pathophysiology, and the anti-ferroptosis effects of treadmill exercise have been reported in other neurological diseases except for TBI. In addition to cytokine induction, recent evidence has demonstrated the involvement of the stimulator of interferon genes (STING) pathway in ferroptosis. Therefore, we examined the possibility that treadmill exercise might inhibit TBI-induced ferroptosis via STING pathway. In this study, we first found that a series of ferroptosis-related characteristics, including abnormal iron homeostasis, decreased glutathione peroxidase 4 (Gpx4), and increased lipid peroxidation, were detected at 44 days post TBI, substantiating the involvement of ferroptosis at the chronic stage following TBI. Furthermore, treadmill exercise potently decreased the aforementioned ferroptosis-related changes, suggesting the anti-ferroptosis role of treadmill exercise following TBI. In addition to alleviating neurodegeneration, treadmill exercise effectively reduced anxiety, enhanced spatial memory recovery, and improved social novelty post TBI. Interestingly, STING knockdown also obtained the similar anti-ferroptosis effects after TBI. More importantly, overexpression of STING largely reversed the ferroptosis inactivation caused by treadmill exercise following TBI. To conclude, moderate-intensity treadmill exercise rescues TBI-induced ferroptosis and cognitive deficits at least in part via STING pathway, broadening our understanding of neuroprotective effects induced by treadmill exercise against TBI.
Ecophysiological Responses of the Intertidal Seaweed Fucus Distichus to Temperature Changes and Reduced Light Driven by Tides and Glacial Input
Authors: Umanzor Schery , Sandoval-Gil Jose Miguel , Conitz Jan 
Published: May 2023

Abstract
Climate change is influencing the performance and distribution of macroalgae in the marine environment. Although intertidal seaweeds successfully adapt to extreme and rapid abiotic changes, exposure to persistent or prolonged potentially stressful conditions can affect their vitality and productivity. Rapid glacial melt can severely alter seawater physicochemical characteristics for shallow and intertidal seaweed communities on the Alaskan coasts. Understanding how intertidal macroalgae respond to this complex mosaic of stressors is key to assessing their ability to adapt to a climate change scenario. This study assessed whether specific stress responses and acclimation mechanisms were exhibited by the intertidal brown seaweed Fucus distichus subsp. evanescence may enable it to cope with changing temperatures and reduced light availability linked to tides and glacial inputs. We analyzed its physiological performance, including photobiological variables, nutrient content, nitrate uptake, and oxidative stress descriptors under strictly controlled laboratory conditions. Results show that this subspecies of Fucus distichus may be relatively unaffected by changes in light and temperature driven by glacial melt due to the presence of pre-adapted strategies that collectively express wide physiological tolerances. Outcomes provide insights into some of the mechanisms of stress tolerance of this major structuring seaweed across the Alaskan coast. Nonetheless, glacial melt would also lower salinity in coastal water, potentially resulting in osmotic stress and other physiological effects not explored here.
Parental Influence on Child Mental Health Post-Hurricane Harvey
Authors: Short Mary B. , Kaye Savannah , Knight Cory , Riobueno-Naylor Alexa , Lai Betty , Elkins Sara , Schanding Thomas , Bistricky Steven L. 
Published: May 2023

Abstract
Purpose
Many children who face natural disasters experience significant mental health consequences. Parents play a prominent role in the likelihood of child mental health outcomes after a weather-related disaster. This study aimed to examine the relationship between parent risk factors and children’s psychological well-being post Hurricane Harvey.

Methods
Parents (n = 140) completed a survey that measured hurricane exposure, parental depression and anxiety, parenting behaviors, and assistance given and received during or after Hurricane Harvey. Additionally, parents were asked to complete questionnaires assessing one of their children’s post-disaster psychosocial functioning and distress.

Results
Results indicated that heightened parent anxiety was significantly associated with an increased risk for emotional symptoms, conduct problems, and hyperactivity-inattention symptoms in children. Additionally, inconsistency in parental discipline was significantly associated with an increased risk of child conduct problems. Further, higher numbers of assistance types received by parents—a proxy indicator of resource loss—was associated with higher child emotional distress scores.

Conclusions
Broader systems-level interventions that address parents’ physical and emotional needs may help mitigate maladaptive reactions in children and facilitate greater post-disaster psychosocial adjustment.
Validating algorithms designed for fertilization control in rice farming system
Authors: Bamurigire Peace , Vodacek Anthony 
Published: May 2023

AbstractRice yields in Rwanda seldom reach values expected for irrigated production, in part due to poor fertilization management. To adapt well-known best practices to local conditions, two fuzzy fertilization algorithms were designed for conditions of rice production in Rwanda. Fuzzy algorithms have a linguistic rule base of 183 IF THEN statements linking measurable field conditions to crop yield. Interviews with government agricultural experts and published knowledge of site conditions were used to create the rule base which incorporates the known nutrient requirements of the different growth stages of rice. Fuzzy algorithms are intended for use in an Internet of Things (IoT) system. To validate the algorithms, historical weather and field data are used to drive yield simulations for different plots during the first growing season of 2020 at sites in northeast Rwanda. Predicted yields are compared to measured yields for scenarios with different irrigation levels and fertilization amounts and with and without full Internet connectivity. Insights are provided on the potential of these fuzzy methods to improve rice nutrient management for increased yields in low-income countries are discussed.
Campaign-style Personnel Management: Task Responsiveness and Selective Delocalization during China's Anti-corruption Crackdown, 2013–2020
Authors: Qian Jingyuan , Tang Feng 
Published: May 2023

AbstractThe anti-corruption campaign launched by General Secretary Xi Jinping has been one of the most far-reaching bureaucratic overhauls in modern Chinese history. How has Xi's crackdown on corruption shaped bureaucratic selection at the sub-provincial level? In this paper, we find that the purge has influenced how local ties are weighed in the appointment of prefecture city leaders. While it is common for provincial Party chiefs to appoint locally embedded officials to govern localities without high-profile corruption cases, they tend to appoint outside officials without local experience and connections to manage cities whose ex-leaders have recently been prosecuted for corruption. We argue that the provincial leaders’ objective of installing non-local officials is to exert hierarchical control and oversight in localities affected by corruption. Using an original dataset of all Party secretaries from China's 287 prefecture-level cities between 2013 and 2020, we find a significant divergence in the local embeddedness of officials who are appointed to replace corrupt ex-leaders and the embeddedness of those who fill the vacancies of transferred or retired predecessors. Our study sheds light on how Xi's anti-corruption campaign has reshaped the central–local relations and the logic of political control in China.
The “Wolf Warrior Cycle”: Chinese Blockbusters in the Age of the Belt and Road Initiative
Authors: Yang Xiao 
Published: May 2023

AbstractThis article concentrates on four Chinese blockbuster movies, Wolf Warrior (2015), Operation Mekong (2016), Wolf Warrior 2 (2017) and Operation Red Sea (2018), referring to them collectively as the “wolf warrior cycle” on the basis of their shared themes of China's overseas military actions. To understand why films addressing this topic have emerged since the mid-2010s, the article employs a critical political economy approach and situates the wolf warrior cycle in China's transforming foreign policies. It argues that the Belt and Road Initiative, one of the state's prominent foreign policies and global strategies in this period, played a crucial role in shaping the production of the wolf warrior cycle films under a trend of the politicization of commercial blockbusters in the Chinese film industry. In turn, these films contributed to the formation of the “wolf warrior diplomacy” image by reinforcing the proactiveness of China's diplomacy and nationalistic stereotypes in Chinese society towards international relations.