bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monkeypox-related knowledge and vaccination willingness among HIV-diagnosed and -suspected males: a cross-sectional survey in Changsha
Authors: Zhou Yingying , Wang Jiemin , Xie Zhi 
Published: January 2025

ObjectiveThis study aimed to update baseline data on monkeypox (mpox)-related knowledge and vaccination willingness among human immunodeficiency virus (HIV) diagnosed and suspected males.MethodsThe cross-sectional survey was conducted in Changsha, a provincial capital in China, during 5 JULY to 5 SEPTEMBER 2023. Among the three study groups, the participants in the “previously diagnosed” group were recruited from a cohort of HIV-infected patients. The “newly diagnosed” and the “suspected” groups were recruited from the outpatients and grouped according to their confirmatory test results. The the exploratory factor analysis was firstly applied to capture the latent structure of participants’ response to the questionnaire about monkeypox. The component and factor scores were compared between groups using the Kruskal-Wallis H tests. The chi-square test was then used to assess the difference of mpox vaccination willingness between MSM and non-MSM in each group. Finally, multivariate logistic regression analysis was performed to identify the determinants of vaccination willingness.ResultsA total of 481 males were included in the final analysis. The results revealed that there was a gap in knowledge about monkeypox between the three participant groups. The vaccination willingness rate of HIV-infected participants was above 90%, while the rate in the HIV-suspected group was 72.60%. Multivariate logistic regression analysis revealed that the previously diagnosed group (adjusted odds ratio [aOR] = 0.314, 95% confidence interval [CI]: 0.105–0.940) and the suspected group (aOR = 0.111, 95% CI: 0.034–0.363) had a lower level of vaccination willingness and they were referred to the newly diagnosed group. Participants in the age groups ranging 25–34 (aOR = 0.287, 95% CI: 0.086–0.959) and 35–44 (aOR = 0.136, 95% CI: 0.039–0.478) years showed a lower level of vaccination willingness, referred to the 15–24 year age group. A better knowledge about monkeypox was associated with a higher level of vaccination willingness (aOR = 1.701, 95% CI: 1.165–2.483). Additionally, a considerable percentage of heterosexual individuals in each group indicated their acceptance of monkeypox vaccines.ConclusionAn overall high level of vaccination willingness was observed among HIV-infected and-suspected male individuals with disparities noted among those with different HIV infection status, knowledge levels of monkeypox, and age. Addressing the existing knowledge gap and engaging people with persistent risks—regardless of their sexual orientation—for a timely HIV diagnosis may facilitate vaccine-based mitigation measures against monkeypox.
U-shaped association between sleep duration and frailty in Chinese older adults: a cross-sectional study
Authors: Song Yanliqing , Liu Haoqiang , Gu Kenan , Liu Yue 
Published: January 2025

ObjectiveAs the population ages, understanding the association between sleep patterns and physical frailty in older adults is crucial for formulating effective health interventions. This study aimed to explore the relationship among nap time, nighttime sleep duration, and physical frailty in older Chinese individuals; establish recommended sleep times; and provide a scientific and reasonable basis for the prevention and management of frailty in older adults.MethodsOn the basis of the 2020 China Health and Retirement Longitudinal Study database, demographic information, health data, and lifestyle information of the research subjects were obtained. A total of 5,761 survey participants were included, and logistic regression and restricted cubic splines were used to explore the association between sleep duration and frailty.ResultsIn our cross-sectional analysis, the duration of napping in older adults did not show a significant correlation with frailty. The optimal nighttime sleep interval for older adults was 7–8 h, and the maximum health benefit was achieved when nighttime sleep reached 7.5 h. Compared with older adults in China who slept 6–8 h at night, those with a sleep duration of &lt;6 h (OR = 1.58, 95% CI: 1.36–1.82) were more likely to be frail. After adjusting for all covariates such as smoking, multimorbidity, self-rated health, social events, education level, and frequency of physical activity, we found no interaction between gender and age concerning sleep duration.ConclusionThe potential correlation between nighttime sleep duration and frailty in older adults is basically U-shaped. Older Chinese adults with a moderate nighttime sleep duration of 7–8 h exhibited the lowest likelihood of frailty than their counterparts. The duration of napping is not related to the likelihood of frailty in older people. Thus, the importance of sufficient nighttime sleep for the health of older adults must be emphasized.
Perceived benefits, costs, and relationships on provincial doctors’ inclination to participate in urban–rural medical consortia in Central China: a social exchange theory perspective
Authors: Zhang Bowen , Ma Liang , Ma Wenjie , Kang Dingding , Mao Yiqing 
Published: January 2025

ObjectiveThis study aims to investigate the perceived benefits, costs, and relationships that influence doctors’ inclination to participate in urban–rural medical consortia (URMC). Furthermore, the study analyzes how perceived relationships moderate the impact of perceived benefits and costs on the inclination to take part in URMC.MethodsThe study was conducted between September 2022 and June 2023 utilizing an online survey in Henan Province, Central China, which included 749 respondents from provincial hospitals. Chi-square and hierarchical logistic regressions were used to determine the perceived factors of the participants’ inclination.ResultsThe study indicated that 85.4% doctors demonstrated a strong inclination to participate. Doctors who perceived significant financial benefits, non-financial benefits, and relationships had a high level of inclination to participate. Doctors who perceived high executive costs and technical costs were less likely to express a high level of inclination to participate. When doctors perceived a strong relationship, the influence of perceived non-financial benefits on their inclination to participate tended to be weaker.ConclusionThis study enhances the understanding of physicians’ motivations for participating in URMC and may inform program leadership and policymakers concerned with developing or enhancing rural medical services. It is essential for managers to enhance incentive mechanisms, strive to minimize both actual and perceived costs, and facilitate the establishment of high-quality professional relationships between provincial physicians and their counterparts in county-level healthcare institutions.
Growth dynamics of Indian infants using latent trajectory models in pooled survey datasets
Authors: Saji Aswathi , Baby Jeswin , Antony Prem , Sinha Srishti , Bandyopadhyay Sulagna , Jose Joby K. , Kurpad Anura V. , Thomas Tinku 
Published: January 2025

BackgroundNational survey data show that age- and sex-standardized weight and length measurements decline early in Indian children. In population-level longitudinal data, early detection of growth trajectories is important for the implementation of interventions. We aimed to identify and characterize distinct growth trajectories of Indian children from birth to 12 months of age residing in urban and rural areas.MethodsPooled data from four interventional and non-interventional longitudinal studies across India were used for the analysis. Latent class mixed modeling (LCMM) was employed to identify groups of children with similar trajectories over age. The trajectories named Classes of Children were created for length-for-age Z scores (LAZ) and weight-for-age Z scores (WAZ) based on place of birth, residential area, and maternal education.ResultsWe identified two latent classes for LAZ in boys and three latent classes for LAZ in girls, and four classes for WAZ were identified in both boys and girls. The first class for LAZ, with the highest proportion of children (&gt;80% of children), did not decline or increase with age; In boys, Class 1 was close to the WHO median, whereas in girls, Class 1 was lower than the WHO median from birth. The LAZ classes of remaining boys and girls declined with age (slope, μdg= − 1.04; 95% CI: −1.09, −0.99 for boys and μdg= − 0.69; 95% CI: −0.76, −0.63 for girls). The first trajectory of WAZ (approximately 50% of children) for boys (μdg=0.13; 95% CI: 0.11, 0.16) and the second trajectory of WAZ for girls (μdg=0.24; 95% CI: 0.18, 0.30) increased with age, while the remaining trajectories of WAZ declined with age.ConclusionThere is heterogeneity in the growth of Indian children in the first year of life, which was identified by distinct types of growth trajectories. The predominant trajectories of both LAZ and WAZ did not decline with age, while most other trajectories demonstrated an initial decline.
Nested case-control study investigating factors affecting initial adoption of HIV self-testing among men who have sex with men in Guangzhou, China: amidst comprehensive service coverage
Authors: Gu Yuzhou , Yang JiaLi , Luo Yefei , Zhan Lishan , Liu Fanghua , Zeng Wenting , Xu Huifang , Lu Yongheng , Cai Yanshan , Han Zhigang 
Published: January 2025

BackgroundChina has been exploring HIV self-testing (HIVST) among men who have sex with men (MSM) since 2014. Currently, both non-profit and commercial initiatives HIVST services have achieved comprehensive coverage. Investigating the factors influencing the initial adoption of HIVST among MSM in this context can help develop tailored HIVST service strategies of and further promote HIVST adoption among MSM communities.MethodsWe selected 230 participants from a prospective cohort on HIV infection among MSM population in Guangzhou, China, who had no prior experience of HIVST. Among the study participants, 43 who initially adopted HIVST during the follow-up period were designated as the case group, while the rest comprised the control group. Electronic questionnaires were used for baseline and follow-up surveys to collect demographic information, sexual behavior characteristics and HIVST utilization in the past 6 months. Logistic regression models were applied to analyze the factors influencing the initial adoption of HIVST.ResultsAmong the study participants, 18.7% (43/230) initially adopted HIVST during the follow-up period. Multivariate logistic regression analysis revealed that individuals who primarily sought sexual partners through offline venues in the past 6 months (aOR = 5.28, 95% CI: 1.01–27.79), had more than one sexual partner in the past 6 months (aOR = 2.76, 95% CI: 1.33–5.74), engaged with more than two casual partners in the past 6 months (aOR = 3.02, 95% CI: 1.35–6.78), or had more than one regular partner (aOR = 3.37, 95% CI: 1.51–7.51) exhibited an increased likelihood of initiating HIVST.ConclusionIn the context of comprehensive promotion and coverage of HIVST service, the development of personalized, adaptable, and innovative HIVST strategies for MSM with a higher number of sexual partners, particularly those in regular partnerships and those seeking partners offline, may further increase the adoption of HIVST among MSM.
The effect of blood flow restriction training on core muscle strength and pain in male collegiate athletes with chronic non-specific low back pain
Authors: Liu Yixuan , Liu Jiahuan , Liu Min , Wang Minzhuo 
Published: January 2025

ObjectiveThe objective of this study is to compare the effectiveness of low-load blood flow restriction training (LL-BFRT) to heavy-load resistance training (HL-RT) in male collegiate athletes with chronic non-specific low back pain (CNLBP).MethodsTwenty-six participants were randomly assigned to LL-BFRT (n = 13) or HL-RT (n = 13). All participants supervised exercises (deep-squat, lateral pull-down, bench-press and machine seated crunch) cycled 4 times per week for 4 weeks (16 sessions). LL-BFRT was done at 30% 1-repetition maximum (1RM) with 70% arterial occlusion pressure (AOP). HL-RT was done at 70% 1-RM. The outcomes were isokinetic core strength, isometric core endurance, pain intensity, and lumbar function disability level, measured at baseline and 4 weeks. Intra-group differences were evaluated using t-tests.ResultsPain intensity and function disability level in LL-BFRT had extremely significant improvement at 4 weeks (p &lt; 0.001, ES = 1.44–1.84). Participants in LL-BFRT and HL-RT showed significant differences in core extensors peak torque-body weight ratio (PT/BW) at isokinetic 120°/s and 30°/s, respectively (LL-BFRT: p = 0.045, ES = 0.62; HL-RT: p = 0.013, ES = 0.81). Isometric core extensor endurance was significantly increased in both groups (LL-BFRT: p = 0.016, ES = 0.78; HL-RT: p = 0.011, ES = 0.83).ConclusionFour weeks of LL-BFRT significantly reduced pain and functional disability while inducing similar strength gains as HL-RT in male collegiate athletes with CNLBP. Thereby, BFRT may qualify as a valuable training strategy for people with physical limitations.
Sex and gender differentials in the prevalence of obesity and its association with multimorbidity among reproductive-aged individuals in India
Authors: Murmu Jogesh , Sinha Abhinav , Agrawal Ritik , Rout Bhagyashree , Kanungo Srikanta , Pati Sanghamitra 
Published: January 2025

IntroductionThe increase in the prevalence of obesity has become a common public health issue worldwide, with low- and middle-income countries (LMICs) like India witnessing an equal rise. It makes a considerable contribution to chronic diseases as it is a major risk factor for other chronic illnesses. Multimorbidity, or the presence of two or more chronic illnesses, is becoming more common in LMICs, resulting in poor health outcomes. However, research on obesity and multimorbidity in younger populations in LMICs is scarce, with most studies focusing on older persons. The study analyzed sex differences in the prevalence of obesity among reproductive-aged persons and its association with multimorbidity, as well as investigated their health-seeking behaviors.MethodsData from the National Family Health Survey (NFHS-5) involving 751,831 females and 100,656 males were analyzed. Multimorbidity was defined by the presence of two or more chronic conditions out of the eight included chronic conditions. Multivariable logistic regression was applied to identify factors associated with obesity.ResultThe prevalence of obesity was 48.90% (95% CI: 48.60–49.20%) among males and 57.10% (95% CI: 57.00–57.22%) among females. Waist-to-Hip Ratio (WHR) revealed higher obesity rates in females with multiple chronic conditions (70.8%) compared to males (65.1%). Males with multimorbidity had a 47% higher likelihood of having obesity (AOR: 1.47, 95% CI: 1.13–1.89, p &lt; 0.003) compared to individuals without obesity.ConclusionThe study highlights high obesity prevalence among reproductive-aged individuals in India, with females having higher obesity rates overall. However, males with multimorbidity exhibit a significantly greater likelihood of obesity than males without. These findings emphasize the need for gender-specific public health strategies addressing obesity and multimorbidity, including promoting healthier diets, increasing physical activity, and improving disease management for both women and men.
Relationship of smoking cessation duration and cognitive function among middle-aged and older adults in China: a national cross-sectional study
Authors: Zuo Wenhang , Peng Jin , Wu Jinhui 
Published: January 2025

BackgroundPopulation aging and smoking are both major challenges worldwide, particularly in developing countries. We preliminarily explored the relationship of smoking cessation duration and cognitive function among middle-aged and older Chinese.MethodsThe data comes from China Health and Retirement Longitudinal Study (CHARLS) wave 4. Smoking information was collected by standardized questionnaire. Global and memory-specific cognitive functions were assessed. We used restricted cubic spline to explore curvilinear relationship. After discretizing the duration of ex-smokers (quitting ≤2 years, 3–8 years, 9–19 years, and ≥20 years), multiple linear regression models were established with current smokers as reference.ResultsA total of 5,561 respondents (67.7 ± 6.2 years; 54.1% men) were included. Respondents who quit smoking for longer showed better global cognitive function. This trend leveled off among respondents who had quit smoking for ≥20 years. There were significant differences in global cognitive function among those who quit smoking for ≥9 years (9–19 years, β = 0.75, 95%CI 0.32–1.18; ≥20 years, β = 0.94, 95%CI 0.42–1.46). The differences mainly came from men. In immediate memory, all ex-smokers performed better. In delayed memory, only those quit for ≥9 years had significant differences.ConclusionCompared with current smokers, both never smokers and ex-smokers showed better cognitive function. Respondents who quit smoking for longer had better cognitive performance, especially those who had quit for at least 9 years.
Cultural and urban city living expectations of knee motion in a Southeast Asian city: implications on total knee arthroplasty outcomes
Authors: Tan Yong Yao , Ang Ke Xin Magneline , Wong Ching Yi Aliza , Mehta Kinjal Vidyut , Loh Sir Young James 
Published: January 2025

BackgroundThe prevalence of knee osteoarthritis in Southeast Asia has increased steadily over the years. When conservative management options fail, total knee arthroplasty (TKA) is a reliable surgical option. Despite over 90% post-operative satisfaction, the high volume of TKAs performed means that even a small percentage of dissatisfied patients holds significance. Dissatisfaction often arises from unmet expectations, which are influenced by cultural and urban factors specific to the region. Surgeons must counsel patients on likely post-operative activities, but limited data on knee range of motion (ROM) for daily tasks in Southeast Asia renders personalised guidance challenging.AimThe primary aim of this study was to evaluate the minimum knee ROM required for daily activities (walking, stair climbing, squatting, kneeling, and sitting cross-legged) in a healthy Southeast Asian urban population. The secondary aim was to determine the association between anthropometric measurements and knee ROM required for the activities. This information is useful in managing patient expectations after TKA.MethodsAn email describing the study was sent to hospital staff to recruit them as volunteers for the study. Enrolled participants were required to be between the ages of 21 and 65 years and capable of providing informed consent. Interested volunteers with a past medical history involving the lower limbs and spine were excluded. Those with a history of lower limb joint pain or back pain within the last 1 year were also excluded. The KINEXCS KIMIA device (KIMIA Recover System, 2022 edition v1.0) was used to measure the knee ROM. The overall characteristics of participants were summarised using descriptive statistics. Anthropometric measurements and their association with knee ROM during the various activities were analysed. Variables with p-values &lt;0.3 in univariate analysis were included in the multivariable analysis.ResultsFifty participants (32 men, 18 women) were enrolled in the study. The average age of participants was 28.5 years (SD 5.57). The average height was 168 cm (SD 0.0870), and the average body mass index was 23.02 kg/m2 (SD 2.82). The average knee ROM requirements for various activities are as follows: walking on flat ground and stair climbing required less than 90°, squatting and kneeling required at least 127°, and sitting cross-legged required 106°. Lower limb length, leg length, and calf circumference were significantly correlated with the knee ROM required to perform the activities.SignificanceThe findings of this study, combined with an understanding of cultural expectations, might prove valuable for counselling and managing patients undergoing TKA in an urban Southeast Asian country.
Effect of dry needling, ischemic compression and cross-taping of the masseter in patients with orofacial myofascial pain: a randomized comparative study
Authors: Macedo de Sousa B. , López-Valverde N. , López-Valverde A. , Neves D. , Santos M. , Rueda J. A. Blanco 
Published: January 2025

Background and objectiveTemporomandibular disorders, of multifactorial etiology, refer to a series of pathologies that affect the temporomandibular joint and the associated musculature of the orofacial region and are the result of alterations in the physiological relationships of the stomatognathic system, responsible for functions such as chewing, phonation and swallowing. They produce, among other symptoms, mainly pain, which affects the quality of life of the patients who suffer from them. To alleviate the discomfort of neuromuscular pathology in the orofacial region, various therapeutic strategies are employed, ranging from non-invasive to more invasive methods. The aim of the study was to compare the efficacy of three therapeutic methods (dry needling, ischemic compression and cross-taping) in reducing or relieving masseter pain in individuals with orofacial myofascial pain.Materials and methodsA multicenter randomized comparative clinical trial was conducted in 60 subjects over 18 years of age, divided into three groups: dry needling, ischemic compression and cross-taping. Pain intensity was assessed, randomly, by a single blinded evaluator, according to the Numerical Pain Rating Scale in the pre-treatment period, immediately after, 1–2 weeks and one month later.ResultsImmediately after applying the therapies, there was a greater decrease in pain intensity in dry needling, followed by ischemic compression and a smaller decrease in the cross-taping technique (p &lt; 0.0001; p = 0.0001; p = 0.0014, respectively). After 1–2 weeks, there was a noticeable increase in the dry needling technique, however, there was a decrease in pain in the cross-taping technique. After 1 month of application, both dry needling and ischemic compression showed a slight reduction in pain intensity, in contrast to the cross-taping group, which showed an increase in pain intensity.ConclusionsDry needling and ischemic compression were more effective than cross-taping for immediate reduction of orofacial myofascial pain. Further short- and long-term research is needed to confirm these findings.Clinical Trial Registrationclinicaltrials.gov, identifier (NCT0660604).