bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors affecting resilience in Namibian children exposed to parental divorce: a Q-Methodology study
Authors: Van Schalkwyk Janine , Gentz Shelene 
Published: August 2023

IntroductionDivorce is a contributor to family instability within sub-Saharan Africa, and specifically within Namibia, an increasing number of children are exposed to its impact. However, not all children react uniformly to the impact of parental divorce, and many children may be resilient. Understanding what promotes resilience in children post-divorce in African contexts is vital, given the unique socio-cultural context. Therefore, this study aimed to understand how some children are capable of resilience despite exposure to parental divorce in Namibia.MethodsA multiple case study design was employed to assess the lived experiences of children aged 9–12 post-parental divorce in Windhoek. Using the Child and Youth Resilience Measurement (CYRM-12) scale, 24 children exposed to parental divorce were screened for resiliency. The Q-Methodology, with visual material, was utilized with a sub-sample of 12 children who scored high on the CYRM (50% girls, mean age = 11) to eliminate some of the challenges associated with gathering qualitative data from younger children. The PQ Method 2.35 software program was used for data analysis.ResultsBy-person factor analysis identified four statistically significant profiles. A third (33%) of participants loaded on a factor emphasizing “quality parent-child relationships” and a further 33% emphasizing “effective parent conflict resolution.” The final two factors emphasized “healthy school attachment” (17%) and “strong community attachment” (17%). All children emphasized a stable, loving familial environment, and frequent visitation with the non-custodial father.DiscussionOur findings suggest that multiple social ecologies nurture resilience in children exposed to parental divorce in Namibia. Support should be extended beyond the perimeters of the nuclear family, and relationships with extended family members, peer groups, school, and the wider community can play an important role in children's adjustment. The study highlights the importance of contextually grounded resilience as some factors that are emphasized for children from more Western communities do not reflect as strongly in the results of this study. Other factors, including a stronger reliance on community and factors such as the school, peers, and extended family members, may play a bigger role in child resilience post-divorce in Namibia.
Investigating women’s awareness and perceptions on human papillomavirus infection and oropharyngeal cancer in Italy
Authors: Paduano Giovanna , Vaienna Sara , Maisto Giuseppe , Di Giuseppe Gabriella , Pavia Maria 
Published: August 2023

IntroductionThis study explored knowledge, attitudes and behaviors toward human papillomavirus (HPV) infection and oropharyngeal cancer (OPC) among women attending primary care services.MethodsThe cross-sectional study was conducted from September to December 2022 in adult women attending three primary care services in Italy, who were invited to complete a self-administered questionnaire.ResultsOverall, 34.7% of participants know that OPC is HPV-associated; knowledge was higher among women who had personal, familiar or friends’ experience of cancer, and who reported to often seek dental care, whereas it was lower in older women. The perception of risk of developing OPC was high for 26.4% of women and was higher in those who had experienced STD, who knew that early sexual debut is a risk factor for OPC, and who considered useful the role of dentists on the provision of information about OPC. Only 22.5% had received HPV vaccination, but 62% intended to receive it in the future. Moreover, 63.2% believe that HPV vaccination is very useful to prevent OPC and only 27% are concerned about health consequences of HPV vaccination.ConclusionThese findings indicate that women’s awareness of the role of HPV infection in the development of OPC is not satisfactory and underline the role that dentists might have in improving their patients’ awareness on HPV related OPC.
HPV prevalence and genotype distribution in 2,306 patients with cervical squamous cell carcinoma in central and eastern China
Authors: Han Chunrong , Huang Wanqiu , Ye Mei , Zou Rong , Lan Jianyun , Chen Jing , Jiang Jingui , Wang Hongjing , Xia Lin , Luo Jun , Li Dongbin , Geng Jianxiang , Wang Zhihui , Huang Jian 
Published: August 2023

BackgroundTo explore the positivity rate and genotype distribution of human papillomavirus (HPV) in cervical squamous cell carcinoma (CSCC) tissues in central and eastern China and to provide theoretical basis for cervical cancer screening and prophylactic HPV vaccine development in China.MethodsDNA was extracted from paraffin-embedded tissues of CSCC samples and exfoliated cervical cells of cervical cancer screening populations. 23 HPV genotypes were detected by combining polymerase chain reaction (PCR) and reverse dot hybridized gene chip detection technology in 2,306 CSCC tissues and 10,245 cervical cancer screening populations. The genotype distribution of HPV infection was analyzed.ResultsThe overall infection rate of HPVs in 2,306 CSCC patients was 92.71%. The frequency of single-type HPV infection and multiple-type HPV infection were 86.48% and 13.51%, respectively. The most common HPV genotypes detected in Chinese CSCC tissues were HPV-16, HPV-18, HPV-31, HPV-33, HPV-45, HPV-52, HPV-58, and HPV-59. The overall positivity rate of these eight high-risk HPV (HR-HPV) genotypes in HPV-positive CSCC was as high as 96.91%. Of which the positivity rate of seven HR-HPV genotypes related to nine-valent HPV vaccines in HPV-positive CSCC was 95.09%. Meanwhile, the overall infection rates of HR-HPV and low-risk HPV (LR-HPV) in female aged 35–64 years who underwent cervical cancer screening were 13.16% and 1.32%, respectively. The high-frequency HR-HPV genotypes in cervical cancer screening women were HPV-52, HPV-58, HPV-16, HPV-53, HPV-68, HPV-39, HPV-51, and HPV-56, with positivity rates of 2.25%, 1.60%, 1.31%, 1.22%, 0.93%, 0.92%, 0.78%, and 0.74%, respectively.ConclusionAmong women screened for cervical cancer in China, detecting the 8 high-frequency HR-HPV genotypes can reduce technical difficulty and reagent costs, while also improving the efficiency and effectiveness of cervical cancer screening. HPV genotyping assists gynecologists in assessing the risk of HR-HPV-positive cervical intraepithelial neoplasia and guiding them in implementing appropriate interventions. Furthermore, HPV genotyping is helpful for doctors to follow up HR-HPV-positive women and to evaluate the protective effect of HPV vaccine.
Efficient ϵ-Approximate k-Flexible Aggregate Nearest Neighbor Search for Arbitrary ϵ in Road Networks
Authors: Kwon Hyuk-Yoon , Yoo Jaejun , Loh Woong-Kee 
Published: August 2023

Recently, complicated spatial search algorithms have emerged as spatial-information-based applications, such as location-based services (LBS), and have become very diverse and frequent. The aggregate nearest neighbor (ANN) search is an extension of the existing nearest neighbor (NN) search; it finds the object p* that minimizes G{d(p*,qi),qi∈Q} from a set Q of M (≥1) query objects, where G is an aggregate function and d() is the distance between two objects. The flexible aggregate nearest neighbor (FANN) search is an extension of the ANN search by introducing flexibility factor ϕ(0<ϕ≤1); it finds the object p* that minimizes G{d(p*,qi),qi∈Qϕ} from Qϕ, a subset of Q with |Qϕ|=ϕ|Q|. This paper proposes an efficient ϵ-approximate k-FANN (k≥1) search algorithm for an arbitrary approximation ratio ϵ (≥1) in road networks. In general, ϵ-approximate algorithms are expected to give an improved search performance at the cost of allowing an error ratio of up to the given ϵ. Since the optimal value of ϵ varies greatly depending on applications and cases, the approximate algorithm for an arbitrary ϵ is essential. We prove that the error ratios of the approximate FANN objects returned by our algorithm do not exceed the given ϵ. To the best of our knowledge, our algorithm is the first ϵ-approximate k-FANN search algorithm in road networks for an arbitrary ϵ. Through a series of experiments using various real-world road network datasets, we demonstrated that our approximate algorithm always outperformed the previous state-of-the-art exact algorithm and that the error ratios of the approximate FANN objects were significantly lower than the given ϵ value.
Effect of Exogenous and Endogenous Ectoine on Monascus Development, Metabolism, and Pigment Stability
Authors: Gong Pengfei , Shi Ruoyu , Tang Jiali , Wang Jiaying , Luo Qiaoqiao , Zhang Jia’ao , Ruan Xiaochun , Wang Chengtao , Chen Wei 
Published: August 2023

Monascus, a key player in fermented food production, is known for generating Monascus pigments (MPs) and monacolin K (MK), possessing bioactive properties. However, the limited stability of MPs and mycotoxin citrinin (CTN) constrain the Monascus industry. Extremolytes like ectoine, derived from bacteria, exhibit cytoprotective potential. Here, we investigated the impact of ectoine on Monascus purpureus ATCC 16365, emphasizing development and secondary metabolism. Exogenous 5 mM ectoine supplementation substantially increased the yields of MPs and MK (105%–150%) and reduced CTN production. Ectoine influenced mycelial growth, spore development, and gene expression in Monascus. Remarkably, ectoine biosynthesis was achieved in Monascus, showing comparable effects to exogenous addition. Notably, endogenous ectoine effectively enhanced the stability of MPs under diverse stress conditions. Our findings propose an innovative strategy for augmenting the production and stability of bioactive compounds while reducing CTN levels, advancing the Monascus industry.
Activated Expression of Rice DMR6-like Gene OsS3H Partially Explores the Susceptibility to Bacterial Leaf Streak Mediated by Knock-Out OsF3H04g
Authors: Wu Tao , Bi Yunya , Yu Yue , Zhou Zhou , Yuan Bin , Ding Xinhua , Zhang Qingxia , Chen Xiangsong , Yang Hong , Liu Haifeng , Chu Zhaohui 
Published: August 2023

Downy Mildew Resistance 6-like (DMR6-like) genes are identified as salicylic acid (SA) hydroxylases and negative regulators of plant immunity. Previously, we identified two rice DMR6-like genes, OsF3H03g, and OsF3H04g, that act as susceptible targets of transcription activator-like effectors (TALEs) from Xanthomonas oryzae pv. oryzicola (Xoc), which causes bacterial leaf streak (BLS) in rice. Furthermore, all four homologs of rice DMR6-like proteins were identified to predominantly carry the enzyme activity of SA 5-hydroxylase (S5H), negatively regulate rice broad-spectrum resistance, and cause the loss of function of these OsDMR6s, leading to increased resistance to rice blast and bacterial blight (BB). Here, we curiously found that an OsF3H04g knock-out mutant created by T-DNA insertion, osf3h04g, was remarkedly susceptible to BLS and BB and showed an extreme reduction in SA content. OsF3H04g knock-out rice lines produced by gene-editing were mildly susceptible to BLS and reduced content of SA. To explore the susceptibility mechanism in OsF3H04g loss-of-function rice lines, transcriptome sequencing revealed that another homolog, OsS3H, had induced expression in the loss-of-function OsF3H04g rice lines. Furthermore, we confirmed that a great induction of OsS3H downstream and genomically adjacent to OsF3H04g in osf3h04g was primarily related to the inserted T-DNA carrying quadruple enhancer elements of 35S, while a slight induction was caused by an unknown mechanism in gene-editing lines. Then, we found that the overexpression of OsS3H increased rice susceptibility to BLS, while gene-editing mediated the loss-of-function OsS3H enhanced rice resistance to BLS. However, the knock-out of both OsF3H04g and OsS3H by gene-editing only neutralized rice resistance to BLS. Thus, we concluded that the knock-out of OsF3H04g activated the expression of the OsS3H, partially participating in the susceptibility to BLS in rice.
BREEDING VALUE OF HOLSTEIN BULLS IN FARMS OF THE MOSCOW REGION
Authors: ПОПОВ Н.А. 
Published: August 2023

В племенных хозяйствах проведено сравнение групп дочерей-первотелок отдельных быков-производителей с матерями и сверстницами по признакам молочной продуктивности. По результатам анализа показателей потомства предложены быки-производители в группу «отцов-быков» для поддержания генеалогической структуры разводимых линий и закладки новых родственных групп в российской популяции крупного рогатого скота голштинской породы. Отмечались многочисленные повторения улучшающего влияния на качество потомства в нескольких поколениях (за 10—15 лет) у ранее имеющих оценки быков-производителей. По 35 группам дочерей (полусибсам) фактические векторы признаков официальной оценки совпадали по удою на 77,1%, по массовой доле жира — на 65,7% и по массовой доле белка — на 60,0%, что может служить основанием ускоренного использования запаса их семени в популяции породы. Рекомендовано направленно вести подбор к маткам стада молодых проверяемых быков, для которых рассчитаны предварительные индексы генетической ценности (Б), а также учитывать изменчивость среди дочерей по приоритетным признакам селекции, их отклонение от средних значений матерей.
In breeding farms, groups of first-heifer daughters of individual breeding bulls were compared with mothers and peers on the basis of milk productivity. According to the results of the analysis of offspring indicators, breeding bulls are proposed in the group of "bull fathers" to maintain the genealogical structure of the bred lines and to establish new related groups in the Russian population of Holstein cattle. There were numerous repetitions of the improving effect on the quality of offspring in several generations (over 10-15 years) in previously rated bulls-producers. For 35 groups of daughters (half-siblings), the actual vectors of the signs of the official assessment coincided in milk yield by 77.1%, in the mass fraction of fat — by 65.7% and in the mass fraction of protein — by 60.0%, which can serve as the basis for accelerated use of their seed stock in the breed population. It is recommended to purposefully select a herd of young tested bulls to the uterus, for which preliminary indices of genetic value (B) are calculated, as well as to take into account the variability among daughters according to priority selection criteria, their deviation from the average values of mothers.
Síndrome visual informático en escolares peruanos durante la pandemia COVID-19
Authors: Mamani Gilberto Luis , Luis-Velasquez Paola del Pilar , Inciso-Mendo Edgar Salvador , Mendez-Vergaray Juan , Flores Edward 
Published: August 2023

El SVI como problema de salud, también puede tener un impacto económico significativo y sus consecuencias perjudiciales pueden continuar incluso cuando la pandemia haya terminado. Objetivo. Determinar la prevalencia y causas relacionadas del síndrome visual informático (SVI) entre los estudiantes de 12 a 17 años, durante la COVID-19. Materiales y Métodos. Se realizó una investigación de tipo transversal, observacional, analítica y cuantitativa, la población estuvo constituida por 345 estudiantes de educación secundaria, se aplicó una encuesta a través de GoogleForms usando como instrumento, el cuestionario de Computer Vision Sympton Scale (CVSS17). Resultados. Se evidenció que los participantes padecen del síndrome visual informático (SVI) entre un nivel leve a muy severo (67%), la mayoría de los participantes presentan mayor uso de dispositivos digitales por día de 4-6 horas. Sintomatología de fotofobia a pantalla 73,3%, dolor de ojos 69,9% y ardor de ojos 66,4%. No evidencia enfermedades visuales 77.7%; algunos casos eventuales de miopía, astigmatismo, hipermetropía y anisometropía, por lo cual, se concluye que los participantes padecen del síndrome visual informático entre un nivel leve a muy severo (67%). Conclusiones. Se sugiere solicitar un diagnóstico completo que permita tener una información real del daño ocasionado por el SVI.
Les forêts péri-urbaines, milieu de loisir : le cas de la région parisienne à l'époque moderne et contemporaine
Authors: Maroteaux Vincent 
Published: August 2023

Comme espaces de loisir, les forêts de la région parisienne ont connu deux types d'usages.
Ces forêts ont d'abord été le lieu des chasses royales et des promenades de la Cour et du Roi. Après le Second Empire seulement, les chasses officielles se sont réduites et la chasse a pu s'exercer par le biais de locations, avant bien souvent de devenir totalement marginale.
A partir de ce moment en effet, le rapport de la ville à la forêt a changé. Celle-ci a tendu à devenir un espace de tourisme et de détente pour les citadins, alors que la ville ne cessait de croître.
Ces usages ont entraîné des aménagements particuliers de la forêt. Pour la chasse à courre et les promenades du Roi, les forêts sont percées d'un très important réseau de routes en étoiles. La chasse intervient aussi dans les choix d'exploitation. Sous la Restauration, on aménage des tirés spéciaux pour le petit gibier, comme il en subsiste à Marly.
La transformation des forêts péri-urbaines en espaces de récréation citadine entraîne de nouvelles mutations de l'espace forestier. Des réserves «artistiques» sont créées, où l'on exploite seulement les arbres morts, un effort est fait pour diminuer l'impact des coupes, la futaie est étendue (et on s'oriente même actuellement vers une conversion systématique). Cette recherche d'agrément se retrouve dans le recours à des essences ornementales. On aménage aussi aires de jeux, parkings, etc. La forêt péri-urbaine évolue vers le parc, à l'image de ce qui s'est passé dès le siècle dernier pour le Bois de Boulogne.
Se trouve ainsi résolue la question «production ou agrément ?», posée dès l'Ancien Régime. A cette époque, comme au XIXe siècle, cependant, les forêts de la région parisienne, du moins les forêts domaniales, ont toujours été productives et d'un bon rapport à l'exploitation. C'est seulement à la suite des instructions ministérielles de 1964 que le rôle récréatif des forêts de l'Ile-de-France à commencé à l'emporter sur leur fonction productive.
Une ville et sa forêt : Auxonne (Côte d'Or), 1669-1900
Authors: Brosselin Arlette 
Published: August 2023

Mentionnée pour la première fois dans une sentence du bailli du Dijonnais en faveur des habitants d'Auxonne en date de 1298, la forêt des Crochères couvre plus de 2.600 arpents dès l'époque moderne. Si sa surface totale varie peu, son état se modifie profondément : un procès verbal (le premier en bonne et dûe forme dont nous disposions) de 1740 précise que la forêt exige un recépage complet, sauf dans un canton de 47 arpents «moins endommagé, dégradé et déshonoré»...
Au début du XXe siècle, il s'agit d'un beau taillis sous futaie totalement productif.
Quel fut le rôle dans cette évolution des administrations forestières et municipales successives ? Quel fut celui des besoins pesant sur la forêt ? Besoins habituels des riverains, mais aussi besoins particuliers d'une ville-frontière entre Bourgogne et Comté, restée place-forte tout au long du XIXe siècle.
Quelques rapports symboliques entre la ville et la forêt
Authors: de Viviès Bertrand 
Published: August 2023

La vertiente norte de la Montaña Negra consta de grandes bosques. Para los ciudadanos del piemonte, estos bosques representaron durante mucho tiempo lugares mágios de donde surgían personajes o animales susceptibles de ejercer una influencia benefica o maléfica, sejún los casos.
Así es como se percibe el bosque : conservatorio de las fuerzas vivas, brutales o profilácticas. Se presenta como un espacio virgen y purificador, opuesto a las ciudades generadoras de miasmas y de enfermedades.
La sociedad mítica de los bosques (duendes, trasgos) posee como el universo ciudadano, una jerarquía, pero no se ve sometida a ninguna de las obligaciones materiales que pesan sobre los hombres. Esta libertad evoca la edad de oro primitiva.
Entre ciudad y bosque se inscribe un espacio indeciso en el que caben seres híbridos, mensajeros de la naturaleza para la gente de la ciudad, incapaz en lo sucesivo de penetrar los secretos de los espacios vírgenes.
Las fundaciones medievales en el bosque se realizan mediante una señal que manifiesta que el lugar escogido resulta puro y protegido, porque la naturaleza siempre suscita la aprensión de los hombres venidos de los espacios domésticos «cultivados».
La gente se proteje del bosque con la implantación de cruces y con conjuros rituales. Ambos delimitan recintos simbólicos en los que se neutralizan los poderes del mal.
En Castelnau de Montmirail, a las fuerzas malignas del bosque se le opone un bosque sagrado, el de la Cruz. Además, la linde del bosque de Gresigne está jalonada con lugares de culto cuya función es la de contener a los seres maléficos. Esta frontera posee virtudes positivas : las mujeres vienen a buscar la fecundidad. Un personaje como Jean de l'Ours, extrañamente resucitado en la Montaña Negra bajo la forma de Simon de Monfort, ilustra maravillosamente la ambivalencia de las relaciones simbólicas entre la ciudad y el bosque.
Difficultés d'approvisionnement en grand bois et innovation technique dans la charpente française des Temps Modernes
Authors: Pérouse de Montclos Jean-Marie 
Published: August 2023

The lack of large wood stimulated technical innovations in the timber domaine. The long 16th C and up to about 1640 was a period particularly fertile in the royal domaine. The movement is renewed as of 1750. New ideas of Northern France appear to be inscribed in the movement of a come-back of Antiquity, which is in fact a return to Mediterranean culture, forms and techniques.
Diffusion of masonry in France is both diffusion of a cultural model and the solution to a technical problem : that of large wood.
Incendies et reconstruction des villes : l'exemple breton au XVIIIe siècle
Authors: Nières Claude 
Published: August 2023

Le renouvellement normal du bâti dans les villes petites et moyennes n'imposait pas une importante consommation des bois, en particulier de bois de charpente. Depuis le XVIe siècle au moins, il existait des réglementations qui tentaient d'en limiter l'usage pour empêcher les incendies (défense de couvrir en bardeaux, d'élever des murs extérieurs en bois ou en pans de bois). L'étude des constructions montre que l'on continuait néanmoins à construire selon les usages anciens. Mais la raréfaction des grands arbres, des chênes surtout, contraignit à modifier, non pas la nature des maisons, mais les techniques de construction.
La destruction par incendie de nombreuses maisons, la disparition de quartiers entiers (voire des trois quarts de la ville-haute comme à Rennes) réactivaient les réglementations anciennes ou conduisaient les autorités à en prendre de nouvelles. L'usage du bois fut désormais circonscrit à la charpente des couvertures, à la menuiserie interne (planchers là où en existait l'usage ; huisserie ; panneaux de bois sur les cloisons là où, au XVIIIe siècle, on n'utilisait pas le plâtre). Ici ou là, on gardait cependant la possibilité d'élever des murs sur cour en torchis. Cette réglementation, quand elle était appliquée, avait pour conséquence d'augmenter le prix des maisons de un tiers à deux tiers par rapport au mode ancien de construction, ce qui explique à la fois les réticences et les détournements dont nous possédons de nombreux exemples.
Quand il s'agissait de reconstruire à une vaste échelle, il fallait trouver de grandes quantités de bois que les forêts (en tout cas de Bretagne) avaient quelque mal à fournir. Il est intéressant d'insister sur les besoins concurrentiels et complémentaires des constructeurs civils et de la Marine qui se partageaient les coupes.
L'étude des incendies et des reconstructions qui s'en suivent permettent du même coup de mieux mesurer les conséquences des choix retenus par les propriétaires (Domaine ou particuliers) en matière de politique forestière.