bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antidepressant-induced mania in panic disorder: a single-case study of clinical and functional connectivity characteristics
Authors: Kim Byung-Hoon , Kim Seung-Hyun , Han Changsu , Jeong Hyun-Ghang , Lee Moon-Soo , Kim Junhyung 
Published: May 2023

BackgroundMental health issues, including panic disorder (PD), are prevalent and often co-occur with anxiety and bipolar disorders. While panic disorder is characterized by unexpected panic attacks, and its treatment often involves antidepressants, there is a 20–40% risk of inducing mania (antidepressant-induced mania) during treatment, making it crucial to understand mania risk factors. However, research on clinical and neurological characteristics of patients with anxiety disorders who develop mania is limited.MethodsIn this single case study, we conducted a larger prospective study on panic disorder, comparing baseline data between one patient who developed mania (PD-manic) and others who did not (PD-NM group). We enrolled 27 patients with panic disorder and 30 healthy controls (HCs) and examined alterations in amygdala-based brain connectivity using a seed-based whole-brain approach. We also performed exploratory comparisons with healthy controls using ROI-to-ROI analyses and conducted statistical inferences at a threshold of cluster-level family-wise error-corrected p &lt; 0.05, with the cluster-forming threshold at the voxel level of uncorrected p &lt; 0.001.ResultsThe patient with PD-mania showed lower connectivity in brain regions related to the default mode network (left precuneous cortex, maximum z-value within the cluster = −6.99) and frontoparietal network (right middle frontal gyrus, maximum z-value within the cluster = −7.38; two regions in left supramarginal gyrus, maximum z-value within the cluster = −5.02 and −5.86), and higher in brain regions associated with visual processing network (right lingual gyrus, maximum z-value within the cluster = 7.86; right lateral occipital cortex, maximum z-value within the cluster = 8.09; right medial temporal gyrus, maximum z-value within the cluster = 8.16) in the patient with PD-mania compared to the PD-NM group. One significantly identified cluster, the left medial temporal gyrus (maximum z-value within the cluster = 5.82), presented higher resting-state functional connectivity with the right amygdala. Additionally, ROI-to-ROI analysis revealed that significant clusters between PD-manic and PD-NM groups differed from HCs in the PD-manic group but not in the PD-NM group.ConclusionHere, we demonstrate altered amygdala-DMN and amygdala-FPN connectivity in the PD-manic patient, as reported in bipolar disorder (hypo) manic episodes. Our study suggests that amygdala-based resting-state functional connectivity could serve as a potential biomarker for antidepressant-induced mania in panic disorder patients. Our findings provide an advance in understanding the neurological basis of antidepressant-induced mania, but further research with larger cohorts and more cases is necessary for a broader perspective on this issue.
Association of SO2/CO exposure and greenness with high blood pressure in children and adolescents: A longitudinal study in China
Authors: Zhang Yi , Chen Shuo , Chen Li , Wu Yu , Wei Jing , Ma Tao , Chen Manman , Ma Qi , Liu Jieyu , Wang Xinxin , Xing Yi , Wu Lijuan , Li Weiming , Liu Xiangtong , Guo Xiuhua , Ma Jun , Dong Yanhui , Zhang Jingbo 
Published: May 2023

IntroductionWe aimed to investigate the association between greenness around schools, long-term gaseous air pollution exposure (SO2 and CO), and blood pressure in children and adolescents.MethodsFrom 2006 to 2018, a total of 219,956 Chinese children and adolescents aged 7–17 years in Beijing and Zhongshan were included in this longitudinal study. Annual average concentrations of SO2 and CO and the mean values of normalized difference vegetation index around schools were calculated. We used the generalized estimation equation model, restricted cubic spline model, and Cox model to analyze the health effects.ResultsAmong all the subjects, 52,515 had the first onset of HBP. During the follow-up, HBP's cumulative incidence and incidence density were 23.88% and 7.72 per 100 person-year respectively. Exposures to SO2 and CO were significantly associated with SBP [β = 1.30, 95% CI: (1.26, 1.34) and 0.78 (0.75, 0.81)], DBP [β = 0.81 (0.79, 0.84) and 0.46 (0.44, 0.48)] and HBP [HR = 1.58 (1.57, 1.60) and 1.42 (1.41, 1.43)]. The risks of HBP attributed to SO2 and CO pollution would be higher in school-aged children in the low greenness group: the attributable fractions (AFs) were 26.31% and 20.04%, but only 13.90% and 17.81% in the higher greenness group. The AFs were also higher for normal-BMI children and adolescents in the low greenness group (AFs = 30.90% and 22.64%, but 14.41% and 18.65% in the high greenness group), while the AFs were not as high as expected for obese children in the low greenness group (AFs = 10.64% and 8.61%), nor was it significantly lower in the high greenness group (AFs = 9.60% and 10.72%).DiscussionGreenness could alleviate the damage effects of SO2/CO exposure on the risks of HBP among children and adolescents, and the benefit is BMI sensitivity. It might offer insights for policymakers in making effective official interventions to prevent and control the prevalence of childhood HBP and the future disease burden caused by air pollution.
Is sleep apnea truly associated with hearing loss? A nationwide, population-based study with STOP-BANG questionnaire
Authors: Lee Jeon Mi , Lee Hyun Jin 
Published: May 2023

ObjectivesWe aimed to investigate the effect of obstructive sleep apnea (OSA) on hearing ability.MethodsWe retrospectively reviewed the population-based survey data collected by the Korean National Health and Nutrition Examination Survey between January 1, 2019 and December 31, 2020. The data included 3,575 participants who completed the STOP-BANG questionnaire (SBQ) and pure-tone audiometry. OSA risk was assessed using the SBQ, and the hearing level was compared between the risk groups.ResultsAmong the 3,575 participants, 2,152 (60.2%), 891 (24.9%), and 532 (14.9%) were classified as being low, intermediate, and high risk, respectively. The intermediate- and high-risk groups showed significantly worse hearing levels than the low-risk group. When age and sex were adjusted, the hearing level did not differ between the risk groups.ConclusionThe study found that the presence of OSA minimally affected hearing level. Because hearing loss due to hypoxic damage develops over a long period of time, further research on the association between the duration of OSA, rather than the presence or severity of OSA, and hearing loss is needed.
Novel risk patterns of vasovagal reactions in NZ blood donations complicated by COVID-19 restrictions
Authors: Wei Wen-Hua , Smith Meredith , Vera Amber , Meads Kelly , Hessell Jillayne , Reid Laura , Scott Lisa , Burge Asuka , Kirwan Susy , Charlewood Richard , Sadani Deepak , Walkden Deborah , Chand Anup 
Published: May 2023

IntroductionVasovagal reactions (VVRs) are common but complex donor adverse reactions (DAEs) in blood donations. VVRs have been extensively studied with a multitude of risk factors identified including young age, female gender and first-time donor status. How they may interplay remains obscure.MethodsA total of 1,984,116 blood donations and 27,952 immediate VVRs (iVVRs) and 1,365 delayed VVRs (dVVRs) reported between 2011 and 2021 in NZ were used in multivariate logistic regression analyses each concerning donations with iVVRs as cases and those free of DAEs as controls. For each analysis stepwise selection was used to identify the best model and risk factors carrying significant main effects and/or interactions. Identified interactions informed further in-depth regression analyses to dissect iVVR risk patterns.ResultsOver 95% of VVRs were iVVRs that had lower female preponderance and deferrals than dVVRs. iVVRs had a school seasonal pattern in whole blood donations driven by first-time donors from schools/colleges, and interactions between gender and age group differentiating the first-time from repeat donations. Subsequent regression analyses identified the known and novel risk factors of year and mobile collection sites and their interactions. iVVR rates were roundly elevated in 2020 and 2021 probably because of COVID-19 restrictions like facemask wearing. Exclusion of the 2020 and 2021 data removed the interactions with year, but confirmed interactions of gender with mobile collection sites (p = 6.2e-07) in first-time donations only and with age group in repeat donations only (p &lt; 2.2e-16), together indicating young female donors at the highest risk of iVVRs. Our results also revealed that donation policy changes contributed to the year effects; donors had a lower iVVR risk at mobile sites than well-medicalized donation centers probably because of under-reporting.ConclusionModeling statistical interactions is valuable in identifying odds and revealing novel iVVR risk patterns and insights into blood donations.
“Where was this when I was in Physical Education?” Physical literacy enriched pedagogy in a quality physical education context
Authors: Houser Natalie , Kriellaars Dean 
Published: May 2023

IntroductionIn recent years, there has been a call to restructure physical education (PE) practices and outcomes. A physical literacy enriched pedagogy approach would support this change by more intentional design of lesson planning that includes concurrent development of competence &amp; confidence and inclusion of students of all levels of ability, leading to holistic development of the student. Despite this potential, there is little research to date that outlines PE pedagogical practices with physical literacy as a foundation. The purpose was to explore pedagogical practices and perspectives from elementary PE teachers through a physical literacy enriched pedagogy lens in a high-quality PE context.MethodsOne-on-one semi-structured interviews were conducted with a convenience sample of elementary PE teachers within one school division. Interviews with all participants focused on questions related to PE and physical literacy. Thematic analysis was used to analyze the data collected from the audio-recorded interviews.ResultsFour themes were generated based on the semi-structured interviews from six elementary PE teachers from one school division. The results identified key physical literacy enriched pedagogical practices based on four themes: supporting a holistic PE experience based upon physical literacy as an outcome; movement within and beyond PE; inclusive and individualized experiences; and physical literacy practices bringing the school community together. The findings were then connected to the physical literacy cycle and UNESCO components of quality PE.ConclusionsAll participants spoke to how their pedagogy focused on the holistic development and inclusion of their students based upon activation of various feedback pathways of the physical literacy cycle. The themes that emerged and subsequent insight gained from teachers went beyond existing physical literacy cycles, in particular by discussing development of students from cognitive, affective, social and creative (problem solving) perspectives, supporting an expansion to the existing physical literacy cycle as presented.
Valorizing staple Native American food plants as a food resilience resource
Authors: Winstead Daniel J. , Jacobson Michael G. , Di Gioia Francesco 
Published: May 2023

IntroductionIncreased risks from global climate change and sun-blocking global catastrophic risks (such as a nuclear winter), warrant the reevaluation of our food systems and their resilience to these climatic changes. Increasing native agrobiodiversity is a simple way of increasing food system resilience, and despite the vast amount of native genetic resources available in North America, the United States has shown little systematic effort to improve its agrobiodiversity.MethodsWe use a systematic literature review of staple Native American food plants (NAFPs) to determine the current state of research interest among them and suggest species of interest for domestication. The nutrient profiles and nutrient adequacy scores for the most researched staple NAFPs were also collected and calculated.ResultsA total of 174 Staple NAFPs were evaluated through systematic review, resulting in a total of 5302 peer-reviewed articles searched. Our findings show that most NAFPs are understudied and are more commonly seen by the agricultural community as weeds. However, there are a few that have current scientific interest in their value as a potential crop.DiscussionWe discuss the 24 most researched NAFPs and their nutritional content. We also discuss potential actions, protocols, and ethical issues regarding future steps in using NAFPs to increase agrobiodiversity and food resilience in the United States through more resilient agroforestry systems.
On the Cycle Stability and Macroscopic Structure of Iron Oxide Pellets for Thermochemical Hydrogen Storage: Influence of Water Content during the Pelletizing Process
Authors: Huber Lea , Heindl Melanie , Schlosser Marc , Pfitzner Arno , Dawoud Belal 
Published: May 2023

Hydrogen storage based on the repeated reduction and oxidation (redox) reactions of iron oxide/iron composites represents a promising technology. This work is dedicated to studying the influence of the amount of water added during the pelletizing process on the cycle stability and structure of iron oxide pellets. The storage composites were prepared from iron oxide (Fe2O3) and 10 wt.-% support material (cement) with different amounts of water (18 and 33 wt.-%) in a laboratory-scale pelletizing disk. To evaluate the cycle stability of the composites, the kinetics of the redox reactions were experimentally measured at 800 °C in an atmosphere of 50% N2 and 50% H2 (reduction) or 50% steam (oxidation), respectively. Moreover, the structure of the pellets was analyzed by micro-computed tomography scans. It turned out that pellets with higher water contents attained faster kinetics and a higher cycle stability. The sample with the least water content (18 wt.-%) needed about 26 min and 19 min to reach a conversion rate of 80% during the reduction and oxidation reactions of the sixth redox cycle, respectively. In contrast, the sample with the highest water content (33 wt.-%) could achieve the same conversion rate after 18 min (reduction) and 13 min (oxidation) during the ninth redox cycle.
Musculoskeletal Asymmetries in Young Soccer Players: 8 Weeks of an Applied Individual Corrective Exercise Intervention Program
Authors: Theodorou Eleni , Tryfonidis Marios , Zaras Nikolaos , Hadjicharalambous Marios 
Published: May 2023

Introduction: In youth soccer, for examining injury prevention and exercise performance, most of the interventional studies concerning corrective postural asymmetries have applied general intervention programs, ignoring the specific individual corrective needs of each youth player separately. The aim, therefore, of the present study was to examine the effect of 8 weeks of an individualized corrective exercise intervention program on musculoskeletal asymmetries in young soccer players. Materials and Methods: Eighty young male soccer players (age: 14.4 ± 1.2 years; body height: 166.3 ± 9.6 cm; body mass: 59.1 ± 11.5 kg) participated in the current laboratory-based study. A battery of postural and musculoskeletal asymmetry evaluations were initially performed. After the completion of the initial assessment, each player was provided with an individual musculoskeletal asymmetry corrective exercise intervention program which lasted for 8-weeks, with the aim of restoring muscular asymmetries. Following the application of the intervention program, a re-evaluation of their musculoskeletal asymmetries was performed. Results: There was a significant improvement in the primary angle of trunk rotation (r = −0.56, p < 0.001), hamstring flexibility (right: r = −0.55, p < 0.001; left: r = −0.48, p < 0.001), hip external rotation (right: r = −0.46, p < 0.001; left: r = −0.26, p = 0.020), hip internal rotation (right: r = −0.26, p = 0.021; left: r = −0.35, p = 0.002), the opened-eyes Stork Test (right: r = −0.33, p = 0.003: left: r = −0.33, p = 0.003), the closed-eyes Stork Test (right: r = −0.39, p < 0.001; left: r = −0.43, p < 0.001), the Thomas test [right: (χ2(3) = 52.281, p = 0.001, γ^ = −0.751; left: (χ2(3) = 45.832, p = 0.001, γ^ = −0.696)] and of ankle prone passive dorsiflexion (flexed knees) (χ2(2) = 13.019, p = 0.005, V = 0.285). Conclusions: An 8-week individual corrective intervention exercise program may improve postural and musculoskeletal asymmetry status in young male soccer players.
Carbon Elastic and Inelastic Stopping-Power Components for Heavy Ions at Bohr and Higher Velocities
Authors: Sagaidak Roman N. 
Published: May 2023

Carbon stopping power (SP) data for heavy ions (HIs), obtained around Bohr velocities, revealed remarkably lower values than those predicted using the SRIM/TRIM calculations/simulations. An attempt was made to extract the elastic (collisional) and inelastic (electronic) components from the available SP data obtained in experiments. A problem is that essentially, total SP is measured in experiments, whereas electronic SP values, usually presented as the results, are derived via the subtraction of the calculated collisional component from the measured values. At high HI reduced velocities (V/v0)/ZHI2/3≳0.3 (V and v0 are HI and Bohr velocities, respectively, and ZHI is the HI atomic number), the collisional component can be neglected, whereas at Bohr velocities it becomes comparable to the electronic one. These circumstances were used to compare the experimental SP data with the SRIM/TRIM calculations/simulations and to empirically obtain corrections to the collisional and inelastic SP components.
Synergistic Effect of Diet and Physical Activity on a NAFLD Cohort: Metabolomics Profile and Clinical Variable Evaluation
Authors: Calabrese Francesco Maria , Celano Giuseppe , Bonfiglio Caterina , Campanella Angelo , Franco Isabella , Annunziato Alessandro , Giannelli Gianluigi , Osella Alberto Ruben , De Angelis Maria 
Published: May 2023

Together with its comorbidities, nonalcoholic fatty liver disease (NAFLD) is likely to rise further with the obesity epidemic. However, the literature’s evidence shows how its progression can be reduced by the administration of calorie-restrictive dietary interventions and physical activity regimens. The liver function and the gut microbiota have been demonstrated to be closely related. With the aim of ascertaining the impact of a treatment based on the combination of diet and physical activity (versus physical activity alone), we recruited 46 NAFLD patients who were divided into two groups. As a result, we traced the connection between volatile organic compounds (VOCs) from fecal metabolomics and a set of statistically filtered clinical variables. Additionally, we identified the relative abundances of gut microbiota taxa obtained from 16S rRNA gene sequencing. Statistically significant correlations emerged between VOCs and clinical parameters, as well as between VOCs and gut microbiota taxa. In comparison with a physical activity regimen alone, we disclose how ethyl valerate and pentanoic acid butyl ester, methyl valerate, and 5-hepten-2-one, 6-methyl changed because of the positive synergistic effect exerted by the combination of the Mediterranean diet and physical activity regimens. Moreover, 5-hepten-2-one, 6-methyl positively correlated with Sanguinobacteroides, as well as the two genera Oscillospiraceae-UCG002 and Ruminococcaceae UCG010 genera.
Satisfacción de egresados con la formación profesional de una universidad privada del sur de méxico
Authors: Roblero Mazariegos Gudiel , Londoño Miranda Margarita , Pérez Torres Ronald Oswaldo 
Published: May 2023

Para una Institución de Educación Superior (IES), es importante conocer la opinión de sus públicos de interés, dado que esto permite la retroalimentación y mejora de los procesos de enseñanza-aprendizaje. Son los individuos que se encuentran próximos a graduarse, el público de interés en donde se puede alcanzar con más facilidad una evaluación objetiva de los docentes, sus métodos de enseñanza y la calidad de la formación recibida; por ello, el objetivo de la investigación es medir los niveles de satisfacción desde la perspectiva de los egresados respecto a la formación profesional que ofrece la IES en cuestión. Para este fin se realizó un estudio descriptivo y transversal; la población de estudio se integró por 82 graduados universitarios. La recolección de datos se realizó mediante una encuesta de opinión creada para este propósito. La satisfacción fue evaluada en una escala de 1 a 5, en donde 1 corresponde a nada satisfecho y 5 muy satisfecho. El análisis estadístico de las respuestas fue realizado en el programa SPSS versión 24. Los resultados de la encuesta revelan una mediana de 4.44, para la docencia y 4.35 para programas académicos. Los hallazgos reflejan que los egresados refieren un alto nivel de satisfacción con su formación profesional.
معالم النقد الفقهي عند ابن المنذر في كتابه الأوسط
Authors: العبري عبدالرحمن , سميران محمد 
Published: May 2023

تهدف هذه الدراسة إلى بيان مسألة مهمة في الفقه الإسلامي، وهي النقد الفقهي عند ابن المنذر، وقُسِّم البحث إلى مقدمة ومبحثين وخاتمة، ففي المبحث الأول: مفهوم النقد الفقهي ومشروعيته وأهميته، وفي المبحث الثاني: معالم النقد عند ابن المنذر في كتابه الأوسط، والمعايير التي استعملها، وفي الخاتمة أهم النتائج التي توصل إليها البحث.
واعتمد البحث على المنهج الاستقرائي، من حيث تتبع المسائل الجزئية للوصول إلى الكليات، وكذلك المنهج التحليلي الوصفي للوصول إلى الحكم المناسب.
وتوصلت الدراسة إلى أنّ النقد الفقهي عملية تقوم على تصحيح وإصلاح مسار معين على وفق معايير معينة، من خلال تعيين الخطأ وتبيين الصواب، وأن ابن المنذر ركَّز على نقد الأخطاء الاستدلالية بالأدلة الشرعية، وطريقة الاستنباط منها، ضمن معايير تتعلق بالإجماع، ومعيار متعلق بالسنة، ومعيار متعلق بالقياس، وهذه كلها أدلة شرعية تبنى عليها الأحكام، وأيضا معيار إلزام المخالف، وهذا المعيار لنقد أصول الاستدلال والاستنباط والقواعد لدى المخالف.
رعاية حقوق الأطفال في الشريعة الإسلامية (دراسة في ضوء القرآن الكريم)
Authors: حمزة مجدي 
Published: May 2023

يتناول هذا البحث حقوق الأطفال في الشريعة الإسلامية، من حيث إثباتها والاهتمام بها في ضوء القرآن الكريم، ويستمد من ذلك أهميته؛ لتعلقه بالقرآن الكريم المصدر الأول للشريعة الإسلامية من ناحية، وارتباطه برعاية حقوق الإنسان الخاصة بالأطفال من ناحية أخرى.
وقد تضمن هذا البحث دراسة النصوص التي تثبت رعاية حق الأطفال في النسب والدين والحرية، وتكفل لهم الحياة والمحافظة علي النفس والامتلاك والمحافظة علي الملك، وتضمن لهم تعلم الآداب والتربية عليها، وتحقق لهم التدريب علي الأعمال والتأهيل لإدارة الأموال، وذلك من خلال تمهيد وستة مباحث وعشرة مطالب وستة فروع حسب الخطة التي وضعت له.
ومن النتائج التي أسفر عنها البحث، أن رعاية الشريعة الإسلامية لحقوق الأطفال في ضوء القرآن الكريم تؤكد ريادتها وسبقها، وتدل على تميزها في هذا الجانب، ومن توصياته ضرورة نشر حقوق الأطفال كافة التي وردت في الشريعة وترجمتها إلى اللغات الأخرى، لتتمكن الجهات المعنية بذلك من الاطلاع عليها والاستفادة منها.