bluuebunny/crossref_metadata_2025_split huggingface dataset:
Logistic regression analysis on correlation of occlusion asymmetry and temporomandibular disorders
Authors: Guo Donghui , Gao Jie , Qin Wen , Wang Xian , Guo Shaoxiong , Jin Zuolin , Wang Meiqing 
Published: February 2023

Abstract
Background: The association between occlusion and temporomandibular disorders (TMDs) remains obscure. The present purpose was to explore the asymmetrical occlusion feature(s) potentially linked to the temporomandibular disorders.
Methods: One hundred and forty-eight female cases with a chief complaint of malocclusion, 84 had not (Group-ORD1) and 64 had signs of TMDs (Group-ORD2), and additional 84 female cases with a chief complain of TMDs problems and a history of orthodontic therapy were included (Group-TMD). The following six occlusion variables, measured on plaster study casts, wererecorded as 1 for asymmetry and 0 for symmetry: (i) the mesial-distal relationship of the first molar (F1) and canine (F2); (ii) overjet and overbite relationship of anterior (F3) and posterior teeth (F4); (iii) tooth/teeth missing (F5); and (iv) the weight of the asymmetrical occluding pair (F6). F6 was the ratio of the number of occluding pairs in symmetrical relation to the number of tooth pairs. If the ratio was greater than 60%, F6 would be recorded as 0, otherwise it would be recorded as 1. Binary stepwise logistic regression method was used for data analyses.
Results: For Group-ORD2 versus Group-ORD1, the F6 variable was entered in the simple logistic regression model. The F6 variable and the interactions of F1 and F2 (F1*F2) and of F1, F2 and F6 (F1*F2*F6) entered the multivariable logistic regression model (all OR > 2.68). For Group-TMD versus Group-ORD1, the variables and interactions were F1, F5, and F6 (all OR > 2.39), F4 (OR = 0.28), F5*F6, F1*F2*F6, F1*F5*F6, F1*F2*F5*F6 (all OR > 2.78), and F2*F4, F3*F5, and F2*F4*F6 (all OR < 0.13). For Group-TMD versus Group-ORD2, the variables and interactions were F5, F5*F6, F1*F5*F6 (all OR > 4.03), and F4, F4*F6 and F2*F4*F6 (all OR < 0.21) (all P < 0.05). Of the 84 patients in Group-TMD, 39 had one or more missing teeth due to tooth extraction during orthodontic treatment, and 25 of those 39 patients had asymmetric teeth extraction.
Conclusions: Patients with sagittal asymmetry, asymmetrical missing teeth or asymmetrical weight of contact have a higher risk of having TMDs problems which effects could be enhanced by horizontal asymmetry.
Effect of Si on the mechanical and tribological properties of FeCoNiBSiNb amorphous alloy composites prepared by laser melting
Authors: Liu Jian , Cai Zhihai , He Dongyu , Zeng Xiangling , Peng Zhen , Wang Rui , Li Jing 
Published: February 2023

Abstract
[(Fe0.6Co0.2Ni0.2)0.75-0.03xB0.2Si0.05+0.03x]96Nb4 amorphous/crystalline composite layers were fabricated using laser cladding by adjusting the contents of Si (x= 0, 1, 2, 3, 4, 5, 6). The microstructure and tribological performance of the layers were studied. Additionally, the effect of Si on the glass forming ability (GFA) of the layers was understood. Results show that an appropriate Si content can refine the microstructure of the FeCoNiBSiNb laser cladding layers and improve the mechanical and tribological properties. The hardness of the cladding layers increases monotonically with increasing Si contents,when Si (x=0) the corresponding layer has the smallest microhardness (734.2HV0.1) and Si (x=3) the corresponding layer has the largest microhardness (1106HV0.1),whereas the amorphous content and compressive strength increase first and then decrease. When x=2, the fracture strength of the layer reaches the biggest (2880 MPa). When x>2, the fracture strength of the cladding layer decreases as x value increases.On the contrary, the wear volume loss decreases first and then increases as Si contents increase. When the Si content is 10.56 at.% (x=2), the cladding layer exhibits the highest amorphous content (42 %), the biggest compressive strength (2880 MPa), and the best dry friction performance.
Quantitative Approach for Evaluating the Community Resilience along Eastern Coastal City in Fujian Province
Authors: Cui Yuepeng , Gong Kuangmin 
Published: February 2023

Abstract
Increasing number and intensity of hurricanes cause significant impact on local communities every year. The ability to measure the resilience level of community is increasingly seen as a key step in disaster risk reduction. The identification of indicators that are meaningful for evaluating resilience remains a challenge. The main purpose of this work is to promote the understanding of the multidimensional nature of disaster resilience and provide a set of indicators for measuring the resilience at the city level in Fujian province of China. A set of indicators covering built environment, electricity and economic resilience was identified by cointegration test. Then, the well-chosen indicators are combined into a composite index to reflect the spatial-temporal resiliency level of coastal communities across geographical boundaries and the changing process over time. The proposed quantitative model can be used by planners and policy makers to achieve the performance goal of typhoon resilience of effected community and develop strategies for long-term sustainability of regions.
Comparative study of the structure and durability of commercial silicate glasses for food consumption and cosmetic packaging
Authors: Angeli Frédéric , Brunswic Léa , Charpentier Thibault , Gin Stephane , Asplanato Pierre , Kaya Huseyin , Kim Seong 
Published: February 2023

Abstract

Understanding the mechanisms of glass alteration is not only essential to glass science but also to tailor glass regulations like REACh or food contact directives in accordance with consumer security and manufacturers capabilities. Four different commercial glass compositions from four French major glass manufacturers have been investigated: lead crystal glass (fine glassware), soda-lime glass (containers for the perfume and cosmetic industries), borosilicate glass (cooking dishes) and barium glass (tableware). Glass structure has been investigated by solid-state multinuclear MAS NMR spectroscopy to compare the local environment and coordinence of the main elements. Glass powders (63-125 μm) and glass slabs have been altered for 3 years in acetic acid (4 % vol) at pH = 2.4 and a temperature of 70°C. Leaching solution samplings have been regularly operated and solutions were analysed with ICP-AES to determine the release rate of each element. At 7.5 months, the glass slabs were removed from the leaching solution to be analysed by ToF SIMS and Spectroscopic Ellipsometry, yielding alteration depths and elemental distribution of each of the studied composition. As a result, the polymerization of the silicate network, as well as the glass composition, impact the alteration rates. The fully polymerized borosilicate glass shows the highest durability whereas glasses with higher non-bridging oxygen content, have a higher alteration depth considering the alkalis depletion. In the case of lead crystal glass, repolymerization of the silicate network was observed in the course of alteration. Meanwhile, the rate of hydrolysis measured from the release of Si, whatever the glass structure and composition, remained the same under identical alteration conditions.
Public voices on tie-breaking criteria and underlying values in COVID-19 triage protocols to access critical care: a scoping review
Authors: Ramirez Claudia Calderon , Farmer Yanick , Bouthillier Marie-Eve 
Published: February 2023

Abstract

Background
To reduce the arbitrariness in the allocation of rare resources in intensive care units (ICU) in the context of the pandemic, tiebreakers were considered in some COVID-19 triage algorithms. They were also contemplated to facilitate the tragic decisions of healthcare workers when faced with two patients with similar prognosis and only one ICU bed available. Little is known about the public's perspective on tiebreakers.
Objectives
To consolidate the available scientific literature on public consultations, particularly on tiebreakers and their underlying values. Also, to obtain an overview of the key arguments presented by the participating public and to identify potential gaps related to this topic.
Methods
The steps described by Arksey & O'Malley was the preferred method to our approach. Seven electronic databases were searched from January 2020 to April 2022, using keywords for each database: PubMed, Medline, EMBASE, Web of Science, PsycINFO, EBM reviews, CINAHL complete. We also searched in Google and Google Scholar, and in the references of the articles found. Our analysis was mainly qualitative. A thematic analysis was performed to consider the public's perspectives on tiebreakers and their underlying values, according to these studies.
Results
Of 477 publications found, 20 were selected. They carried out public consultations through various methods: surveys (80%), interviews (20%), deliberative processes (15%) and others (5%) in various countries: Australia, Brazil, Canada, China, France, Germany, India, Iran, Italy, Japan, Korea, Netherlands, Portugal, Spain, Switzerland, Thailand, United Kingdom, and United States. Five themes emerged from our analysis. The public favored the life cycle (50%) and absolute age (45%) as a tiebreaker. Other values considered important were reciprocity, solidarity, equality, instrumental value, patient merit, efficiency, and stewardship. Among the new findings were a preference for patient nationality and those affected by COVID-19.
Conclusions
There is a preference for favoring younger patients over older patients when there is a tie between similar patients, with a slight tendency to favor intergenerational equity. Variability was found in the public's perspectives on tiebreakers and their values. This variability was related to socio-cultural and religious factors. More studies are needed to understand the public's perspective on tiebreakers.
Decreased aggressive care at the end of life among advanced cancer patients in Korea: A nationwide study from 2012 to 2018
Authors: Kwon Sara , Kim Kyuwoong , Park Bohyun , Park Sojung , Choi Jin Young , Jho Hyun Jung 
Published: February 2023

Abstract
Purpose: To investigate the trends of aggressive care at the end of life (EoL) for patients with advanced cancer in Korea between 2012 and 2018, and to identify factors affecting such care.
Methods: This was a population-based, retrospective nationwide study. We used administrative data from the National Health Insurance Service and the Korea Central Cancer Registry to analyze 125,350 patients aged 20 years and above who died within one year of a stage IV cancer diagnosis between 2012 and 2018.
Results: The overall aggressiveness of EoL care decreased between 2012 and 2018. In patients’ last month of life, chemotherapy use (37.1% to 32.3%; P< .0001), cardiopulmonary resuscitation (13.2% to 10.4%; P < .0001), and intensive care unit admission (15.2% to 11.1%; P < .0001) decreased during the study period, although no significant trend was noted in the number of emergency room visits. A steep increase was seen in inpatient hospice use in the last month of life (8.6% to 26.6%; P < .0001), while downward trends were observed for hospice admission within three days prior to death (13.9% to 11%; P = .0319). Patients were more likely to receive aggressive EoL care if they were younger, women, had treatment in tertiary hospitals, or had hematologic malignancies. In the subgroup analysis, the overall trend of aggressive EoL care decreased for all five major cancer types.
Conclusion: The aggressiveness of EoL care in stage IV cancer patients showed an overall decrease during 2012–2018 in Korea.
Three-dimensional unsteady phenomenon in extensive interaction area driven by counter-flow jets and rarefied hypersonic free stream based on direct simulation Monte-Carlo simulation
Authors: Wu Junlin , Li Zhong-Hua , Peng Ao-Ping , Li Lang-Quan 
Published: February 2023

Abstract
Based on the Direct Simulation Monte Carlo (DSMC) method, an unsteady flow, which is caused by the interaction of two counter-flow jets with a hypersonic free stream, is constructed and simulated in the rarefied regime for the flight altitude of 90 km. In this complex three-dimensional rarefied flow, although the hypersonic free stream and all counter-flow jets are stable, their interaction area has great instability. This signifies that this extensive interaction area will not reach a final stable state in the DSMC simulation process. This study exhibits the unsteady evolution of the interaction area.
Gestural communication in wild spider monkeys (Ateles geoffroyi)
Authors: Larenas Felipe Villa , Llorente Miquel , Liebal Katja , Amici Federica 
Published: February 2023

Abstract
Gestures play a central role in the communication systems of several species, including primates. In this study, we provide a first assessment of the gestural systems of a Platyrrhine species, Geoffroy’s spider monkeys (Ateles geoffroyi). We observed a wild group of 52 spider monkeys, and assessed the distribution of visual and tactile gestures in the group, the size of individual repertoires, and the intentionality and effectiveness of individuals’ gestural production. Our results showed that younger spider monkeys were more likely than older ones to use tactile gestures, despite no inter-individual differences in the distribution of visual gestures. Repertoire size did not vary with age, whereas the probability of accounting for recipients’ attentional state was higher for older monkeys than for younger ones, especially for gestures in the visual modality. Using vocalizations right before the gesture increased the probability of gesturing toward attentive recipients and of receiving a response, although age had no effect on the probability of gestures being responded. Overall, our study provides first evidence of complex gestural communication in a Platyrrhine species, and confirms this taxon as a valid candidate for research on animal communication.
Nonylphenol induces myocardial fibrosis by activating the TGF- β1/LIMK1 signaling pathway
Authors: Guo Mei , Xu Jie , Liu Weichu , Long Xianping , Aris Ahmad Zaharin , Yang Danli , Luo Ya , Nie Yanling , Yu Jie 
Published: February 2023

Abstract
Objective: The objective was to explore whether perinatal nonylphenol (NP) exposure leads to myocardial fibrosis during adulthood in male rats and to determine the action of the TGF-β1/limk1 signaling pathway in np-induced fibrosis in cardiac fibroblasts (CFs).
Methods and Results: The histopathological results showed increased collagen deposition and altered fiber arrangement in the NP and model groups compared with the blank group. The systolic and diastolic functions were impaired. Western blot and qRT-PCR analysis showed that the central myofibrosis-related proteins (collagen I, collagen III, MMP2, MMP9, TGF-β1, α-SMA, IL-1β, and TGF-β1) and genes (Collagen I, Collagen III, TGF-β1, and α-SMA mRNA) were upregulated in the NP and model groups compared with the blank group. The mRNA-seq analysis indicated differential expression of TGF-β1 signaling pathway. In vitro, fibrosis-related protein and gene expression was increased in CFs under recombinant human TGF-β1 and NP stimulation, which was consistent with the results of animal experiments. Mechanistically, immunofluorescence (IF) and Western blot analysis showed that NP exposure activated the TGF-β1/LIMK1 signaling pathway. The mechanism of TGF-β1/LIMK1 signaling pathway in NP-induced CFs was further validated. LIMK1 inhibitor (BMS-5) modulated the TGF-β1/LIMK1 signaling pathway and then suppressed the NP-induced increase in fibrosis-related protein expression in CFs. These results suggest that the TGF-β1/LIMK1 signaling pathway is involved in NP-induced fibrosis.
Conclusion: Our results provide the first evidence suggesting that perinatal NP exposure causes myocardial fibrosis in growing male rat pups and reveal the molecular mechanism and functional role of the TGF-β1/LIMK1 signaling pathway in this process.
3D Gravity Fast Inversion Based on Krylov Subspace Methods
Authors: Yang Min , Xu Xinqiang , Wang Wanyin , Zhao Dongming , Zhou Wei 
Published: February 2023

Abstract
Mapping the density contrast through the 3D gravity inversion can help detect the goals under the subsurface. However, it is a challenge to accurately and efficiently solve the 3D gravity inversion. The Krylov subspace method is widely used to solve large linear problems because of its small storage capacity and high computational efficiency. In this study, two classical algorithms of Krylov subspace method, i.e., the Generalized Minimum Residual method and the Conjugate Gradient method, are applied to 3D gravity inversion. Based on the results of the deep mineral model and the shallow L-shaped tunnel model tests, the Generalized Minimum Residual method was found to provide density contrast results similar to the Conjugate Gradient method. The distribution position of the density contrast obtained by inversion corresponds well to the position of the deep mineral resources model and the L-shaped tunnel model. The 3D underground distribution of Fe content is obtained by performing inversion of the measured gravity data of the Olympic Dam in Australia, and the obtained results correspond well with the distribution position of Fe content in the collected geological profile. Under the same conditions, the inversion accuracy of the Generalized Minimum Residual method is similar to that of the Conjugate Gradient method. However, the Generalized Minimum Residual method has faster convergence speed than the Conjugate Gradient method, and the inversion efficiency is increased by about 90%, which greatly reduces the inversion time and improves the inversion efficiency.
Effects of Flooding on Traffic Flow in Some Areas in Ado-Ekiti, Nigeria
Authors: AYITI O.M 
Published: February 2023

Abstract
There’s an urgent need to declare a state of emergency on Flooding in Ado-Ekiti, the menace has become an annual unwanted event in the area of focus in the course of this study. Transport is such a unique sector that ensures the functionality of other sectors, without mobility there can’t be growth and development. Primary and secondary data were been adopted and it’s clearly stated that flooding especially in the study area has effect on traffic flow. The sternness is when it is during the peak period, when more people are plying the road. The study recommended that every means of tackling Flooding should be adopted and that there should be an alternative route, media constant and continuous announcement of flood hot spot during prolonged rainfall and that agencies should be available to block such route to avoid traffic interruption that could resultantly generate series of unfortunate problems.
Feasibility of a New Risk Stratification System in Pediatric Anaplastic Large Cell Lymphoma: Result of a Prospective Open-Label Multiple-Institution Study
Authors: Chen Tingting , Zeng Chengong , Liao Ning , Zhang Xiaohong , Chen Zaisheng , Yuan Xiuli , Yang Zhen , Guo Haixia , Yang Liangchun , Wen Chuan , Zhang Wenlin , Li Yang , Luo Xuequn , Wu Zelin , Yang Lihua , Liu Riyang , Zheng Mincui , He Xiangling , Sun Xiaofei , Zhen Zijun 
Published: February 2023

Abstract
Background
The risk stratification of pediatric anaplastic large cell lymphoma (ALCL) has not been unified. Purpose: In this study, new risk factors were included to establish a new risk stratification system for ALCL, and its feasibility in clinical practice was explored.
Methods
On the basis of the non-Hodgkin’s lymphoma Berlin–Frankfurt–Munster 95 (NHL-BFM-95) protocol, patients with minimal disseminated disease (MDD), high-risk tumor site (multiple bone, skin, liver, and lung involvement), and small cell/lymphohistiocytic (SC/LH) pathological subtype were enrolled in risk stratification. Patients were treated with a modified NHL-BFM-95 protocol combined with an anaplastic lymphoma kinase inhibitor or vinblastine.
Results
A total of 136 patients were enrolled in this study. The median age was 8.8 years. The 3-year event-free survival (EFS) and overall survival of the entire cohort were 77.7% and 92.3%, respectively. The 3-year EFS rates of R1, R2, and R3 patients were 100%, 89.5%, and 67.9%, respectively. The prognosis of patients with MDD (+), stage IV cancer, SC/LH lymphoma, and high-risk sites was poor, and the 3-year EFS rates were 45.3%, 65.7%, 55.7%, and 67.9%, respectively.
Conclusions
This study established a new risk stratification system for the precise treatment of pediatric ALCL that is convenient and feasible in clinical practice. Among high-risk patients, patients with SC/LH lymphoma and MDD (+) at diagnosis still need to receive better treatment.
Predictors and outcomes of cutaneous metastatic breast carcinoma: a retrospective, single- institution review
Authors: Choo Zi-Yi , Xu Amy Z. 
Published: February 2023

Abstract
Breast carcinoma is among the most common visceral malignancies to metastasize to the skin, but few studies have comprehensively characterized the patient and breast cancer-specific features of cutaneous metastases of primary breast carcinoma (CMBC). In this case control study, we identified key clinical, histopathologic, and molecular features of CMBC within a large, single-institution cohort. We further stratified between locoregional and distant cutaneous metastases to identify possible predictors of the eventual skin phenotype. Ninety-four (94) histologically confirmed cases of CMBC biopsied between January 2005 and December 2021 were identified via review of the University of Chicago Medicine pathology report database. Of these, 37 were locoregional and 57 were distant cutaneous metastases. The mean duration between diagnosis of breast cancer and CMBC was 7.02 years (range, 0–37 years). Histologically, most primary breast tumors were invasive ductal carcinomas (IDC; 82.2%). On subgroup analysis, older age and underlying invasive lobular carcinoma (ILC) were significantly associated with distant patterns of CMBC (P = 0.026 and 0.008, respectively). Notably, patients with distant CMBC also demonstrated worse functional status, more recalcitrant disease, and higher mortality than those with locoregional CMBC. Our analysis represents one of the largest cohorts to date of CMBC and highlights the importance of longitudinal skin surveillance in the detection of CMBC. Furthermore, our findings suggest that the primary breast cancer subtype may influence the eventual presentation of metastatic disease to the skin, a novel finding that warrants further exploration.
Heavy metal pollution in the Yongjiang Estuary, China and their relations to environmental factors
Authors: Zheng Chunli , Liao Hongkai 
Published: February 2023

Abstract
This study aimed to investigate the relationship between 8 heavy metals (Pb, Cd, Mn, Ni, Cr, Fe, Cu and As) and 11 environmental parameters at five sites during the tide rising and ebbing durations of surface water over four seasons in the Yongjiang Estuary, China. The results found that the change concentrations of heavy metals and environmental factors were high, which had obvious spatial distribution and seasonal dynamic characteristics. In the aspect of spatial distribution, the concentrations of heavy metals and the physical and chemical indexes were higher at the points near the industrial area. In the aspect of seasonal dynamics, the concentrations of Pb, total phosphorus and ammonia nitrogen were the highest in winter. In the aspect of tidal change, the change rules of different indicators were different, among which, the concentrations of Cd, Ni and total nitrogen in the rising tide and ebb tide were quite different. The concentration of dissolved organic carbon, total nitrogen, pH, salinity, ammonia nitrogen and chlorophyll a were positively correlated with target heavy metals. This study explored the relationship between the concentrations of heavy metals and environmental parameters, which is beneficial to future heavy metals research in estuaries.