bluuebunny/crossref_metadata_2025_split huggingface dataset:
(Semi)automated approaches to data extraction for systematic reviews and meta-analyses in social sciences: A living review protocol
Authors: Legate Amanda , Nimon Kim 
Published: January 2023

Background: An abundance of rapidly accumulating scientific evidence presents novel opportunities for researchers and practitioners alike, yet such advantages are often overshadowed by resource demands associated with finding and aggregating a continually expanding body of scientific information. Across social science disciplines, the use of automation technologies for timely and accurate knowledge synthesis can enhance research translation value, better inform key policy development, and expand the current understanding of human interactions, organizations, and systems. Ongoing developments surrounding automation are highly concentrated in research for evidence-based medicine with limited evidence surrounding tools and techniques applied outside of the clinical research community. Our objective is to conduct a living systematic review of automated data extraction techniques supporting systematic reviews and meta-analyses in the social sciences. The aim of this study is to extend the automation knowledge base by synthesizing current trends in the application of extraction technologies of key data elements of interest for social scientists. Methods: The proposed study is a living systematic review employing a partial replication framework based on extant literature surrounding automation of data extraction for systematic reviews and meta-analyses. Protocol development, base review, and updates follow PRISMA standards for reporting systematic reviews. This protocol is preregistered in OSF: (Semi)Automated Approaches to Data Extraction for Systematic Reviews and Meta-Analyses in Social Sciences: A Living Review Protocol on August 14, 2022. Conclusions: Anticipated outcomes of this study include: (a) generate insights supporting advancement in transferring existing reliable methods to social science research; (b) provide a foundation for protocol development leading to enhancement of comparability and benchmarking standards across disciplines; and (c) uncover exigencies that spur continued value-adding innovation and interdisciplinary collaboration for the benefit of the collective systematic review community.
Physiological characteristics of IRR 400 series rubber clones (Hevea brasiliensis Muell. Arg.) on drought stress
Authors: Pasaribu Syarifah Aini , Basyuni Mohammad , Purba Edison , Hasanah Yaya 
Published: January 2023

Background: Drought stress is one of the main causes of plant death. Strategies for plants survival are morphological adaptations, specific signaling pathways, and tolerance mechanisms. Rubber plantations have many uses, such as foreign exchange sources, job sources, forest revitalization, and a source of alternative wood for building materials and furniture. The rubber plant’s response to drought stress is a complex biological process. A tolerant rubber clone in a dry area is the right approach. The present study aimed to determine the mechanism of drought-tolerant clones, based on physiological characteristics, to obtain character selection and drought-tolerant clones early. Methods: The first factor examined for this work was clones (IRR 425, IRR 428, IRR 429, IRR 434, IRR 440, RRIC 100, and BPM 24) and the second factor was water content (30%, 60%, and 90%). The study was arranged on a factorial randomized block design and repeated three times. Characteristics observed were total sugar (µM), proline (mg/L), chlorophyll a, b, total (µg/mL), hydrogen peroxidase (µmol/g), ascorbate peroxidase (unit/mg), superoxide dismutase (unit/mg), and peroxide dismutase (unit/mg). Results: The tolerance ability of the IRR 400 series rubber clones to drought stress was determined by observing the characteristics of sugar total and proline. The concentration of total sugar and proline were higher when the plant was treated with a lower water content. The selected clones tolerant to drought stress are RR 425 and IR 434 with high total sugar content and proline. Other characteristics, namely chlorophyll a, b, and total, as well as hydrogen peroxidase, ascorbate peroxidase, super oxide dismutase, peroxide dismutase, cannot be used as selection characteristics for this study. Conclusions: This drought study of IRR 400 clones with varying water content percentages illustrated that the total sugar and proline characteristics could be used to distinguish tolerance levels from other observed characteristics.
Modeling document labels using Latent Dirichlet allocation for archived documents in Integrated Quality Assurance System (IQAS)
Authors: Prianes Freddie , Palaoag Thelma 
Published: January 2023

Background: As part of the transition of every higher education institution into an intelligent campus here in the Philippines, the Commission of Higher Education has launched a program for the development of smart campuses for state universities and colleges to improve operational efficiency in the country. With regards to the commitment of Camarines Sur Polytechnic Colleges in improving the accreditation operation and to resolve the evident problems in the accreditation process, the researchers propose this study as part of an Integrated Quality Assurance System that aims to develop an intelligent model that will be used in categorizing and automating tagging of archived documents used during accreditation. Methods: As a guide in modeling the study, the researchers use an agile method as it promotes flexibility, speed, and, most importantly, continuous improvement in developing, testing, documenting, and even after delivery of the software. This method helped the researchers in designing the prototype with the implementation of the said model to aid the process in file searching and label tagging. Moreover, a computational analysis is also included to further understand the result from the devised model. Results: As a result, from the processed sample corpus, the document labels are faculty, activities, library, research, and materials. The labels generated are based on the total relative frequencies which are 0.009884, 0.008825, 0.007413, 0.007413, 0.006354, respectively, that have been computed between the ratio on how many times the term was used in the document and the total word count of the whole document. Conclusions: The devised model and prototype support the organization in file storing and categorization of accreditation documents. Through this, it is easier to retrieve and classify the data, which is the main problem for the task group. Further, other patterns in clustering, modeling, and text classification can be integrated in the prototype.
Fact-checking: uma prática recente em Portugal? Análise da perceção da audiência
Authors: Baptista João Pedro , Gradim Anabela , Loureiro Marlene , Ribeiro Fábio 
Published: January 2023

O fact-checking é uma prática jornalística muito recente em Portugal. Nenhum estudo até agora procurou entender a atitude do público em relação a este novo fenómeno. Metodologia: este estudo exploratório, com base em um questionário online (N = 618), teve como objetivo investigar a atitude e a perceção dos portugueses em relação ao fact-checking, analisando o efeito das práticas de consumo de informação, os aspetos sociodemográficos e a orientação política dos indivíduos. Os nossos resultados mostram que a maioria é favorável ao fact-checking e está familiarizada com a prática. No entanto, os níveis de familiaridade são reduzidos e estão abaixo do esperado, uma vez que 40 % dos entrevistados não conhecem este género jornalístico. Além disso, encontramos um ceticismo significativo, por parte dos participantes, em relação à ética dos fact-checkers. Corroborando com outros estudos, os jovens e os mais instruídos são mais favoráveis e mais familiarizados com o fact-checking. Ao contrário de outros estudos, os nossos resultados não mostram qualquer efeito da orientação política e ideológica sobre os níveis de aceitação e familiaridade. Este estudo levanta vários desafios relevantes, demonstrando que as pessoas podem não estar tão familiarizadas com o fact-checking como seria de esperar e que existe uma grande desconfiança no rigor e imparcialidade dos fact-checkers, o que pode ser um obst áculo à correção da desinformação.
Microfoundations of Adaptive Search in Complex Tasks: The Role of Cognitive Abilities and Styles
Authors: Bergenholtz Carsten , Vuculescu Oana , Amidi Ali 
Published: January 2023

Problem-solving in complex environments requires a cognitively demanding search for task solutions. Managing this search process presents a major challenge in organizations. We contribute to the literature on this topic by providing new evidence on the cognitive antecedents that shape how individuals search when engaged in complex problem-solving tasks. We present results from three laboratory studies, wherein 335 individuals solved a complex task. In doing so, they generated behavioral data coupled with survey-based measurements of the individuals’ cognitive styles and performance-based tests of their cognitive abilities. Our data analysis contributes to the current literature by documenting systematic heterogeneity in the persistence and distance of search that can be explained by the participants’ level of creativity, attention to detail, and executive functions. We extend the research on the microfoundations of adaptive search by linking cognitive antecedents with a complex search task, widening our insight into what search behavior certain cognitive microfoundations lead to, and showing how managers can more effectively shape organizational search. History: This paper has been accepted for the Organization Science Special Issue on Experiments in Organizational Theory. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.1654 .
Efficient high-power orthogonal dual-slab Yb:KGd(WO4)2 laser oscillator with a TEM00 mode
Authors: Tu ZhiHua , Guo Jie , Gao YongXi , Gao ZiChen , Liang XiaoYan 
Published: January 2023

We demonstrated a TEM00 mode orthogonal dual-slab Yb:KG(WO4)2(Yb:KGW) laser oscillator with high average power. Polarization anisotropy of thermal lenses was investigated and alleviating the astigmatism based on orthogonal dual-slab. In addition, the laser polarization was directly controlled by adjusting the net gain of the two crystals. The maximum output power was highly enhanced compared with single crystal due to effective thermal distribution. For an absorbed pump power of 52.4 W, this oscillator delivered an average power of 26.5 W, corresponding to an optical-to-optical conversion efficiency of 50.6%. Meanwhile, the ellipticity of the output laser was optimized to 0.940. Nearly diffraction-limited beam quality was measured to be

M
x
2

= 1.19 and

M
y
2

=1.18.
When months matter; modelling the impact of the COVID-19 pandemic on the diagnostic pathway of Motor Neurone Disease (MND)
Authors: Burchill Ella , Rawji Vishal , Styles Katy , Rooney Siobhan , Stone Patrick , Astin Ronan , Sharma Nikhil 
Published: January 2023

Background
A diagnosis of MND takes an average 10–16 months from symptom onset. Early diagnosis is important to access supportive measures to maximise quality of life. The COVID-19 pandemic has caused significant delays in NHS pathways; the majority of GP appointments now occur online with subsequent delays in secondary care assessment. Given the rapid progression of MND, patients may be disproportionately affected resulting in late stage new presentations. We used Monte Carlo simulation to model the pre-COVID-19 diagnostic pathway and then introduced plausible COVID-19 delays.

Methods
The diagnostic pathway was modelled using gamma distributions of time taken: 1) from symptom onset to GP presentation, 2) for specialist referral, and 3) for diagnosis reached after neurology appointment. We incorporated branches to simulate delays: when patients did not attend their GP and when the GP consultation did not result in referral. An emergency presentation was triggered when diagnostic pathway time was within 30 days of projected median survival. Total time-to-diagnosis was calculated over 100,000 iterations. The pre-COVID-19 model was estimated using published data and the Improving MND Care Survey 2019. We estimated COVID-19 delays using published statistics.

Results
The pre-COVID model reproduced known features of the MND diagnostic pathway, with a median time to diagnosis of 399 days and predicting 5.2% of MND patients present as undiagnosed emergencies. COVID-19 resulted in diagnostic delays from 558 days when only primary care was 25% delayed, to 915 days when both primary and secondary care were 75%. The model predicted an increase in emergency presentations ranging from 15.4%-44.5%.

Interpretations
The model suggests the COVID-19 pandemic will result in later-stage diagnoses and more emergency presentations of undiagnosed MND. Late-stage presentations may require rapid escalation to multidisciplinary care. Proactive recognition of acute and late-stage disease with altered service provision will optimise care for people with MND.
Early exposure to farm dust in an allergic airway inflammation rabbit model: Does it affect bronchial and cough hyperresponsiveness?
Authors: Divaret-Chauveau Amandine , Foucaud Laurent , Demoulin Bruno , Teston Cédric , Loison Pauline , Le Cann Pierre , Schweitzer Cyril , De Carvalho Bittencourt Marcelo , Mauny Frédéric , Demoulin-Alexikova Silvia 
Published: January 2023

Introduction
Over the past 50 years, the prevalence of allergic respiratory diseases has been increasing. The Hygiene hypothesis explains this progression by the decrease in the bio-diversity of early microbial exposure. This study aims to evaluate the effect of early-life farm exposure on airway hyperresponsiveness and cough hypersensitivity in an allergic airway inflammation rabbit model.

Method
A specific environment was applied to pregnant rabbits and their offspring until six weeks after birth. Rabbits were housed in a pathogen-free zone for the control group and a calf barn for the farm group. At the end of the specific environmental exposure, both groups were then housed in a conventional zone and then sensitized to ovalbumin. Ten days after sensitization, the rabbit pups received ovalbumin aerosols to provoke airway inflammation. Sensitization to ovalbumin was assessed by specific IgE assay. Cough sensitivity was assessed by mechanical stimulation of the trachea, and bronchial reactivity was assessed by methacholine challenge. The farm environment was characterized by endotoxin measurement.

Results
A total of 38 rabbit pups were included (18 in the farm group). Endotoxin levels in the farm environment varied from 30 to 1854 EU.m-3. There was no significant difference in specific IgE values to ovalbumin (p = 0.826) between the two groups. The mechanical threshold to elicit a cough did not differ between the two groups (p = 0.492). There was no difference in the number of cough (p = 0.270) or the intensity of ventilatory responses (p = 0.735). After adjusting for age and weight, there was no difference in respiratory resistance before and after methacholine challenge.

Conclusion
Early exposure to the calf barn did not affect cough sensitivity or bronchial reactivity in ovalbumin-sensitized rabbits. These results suggest that not all farm environments protect against asthma and atopy. Continuous exposure to several sources of microbial diversity is probably needed.
Involving men in cervical cancer prevention; a qualitative enquiry into male perspectives on screening and HPV vaccination in Mid-Western Uganda
Authors: de Fouw Marlieke , Stroeken Yaël , Niwagaba Ben , Musheshe Mwalimu , Tusiime John , Sadayo Isingoma , Reis Ria , Peters Alexander Arnold Willem , Beltman Jogchum Jan 
Published: January 2023

Introduction
Evidence-based preventive strategies for cervical cancer in low-resource setting have been developed, but implementation is challenged, and uptake remains low. Women and girls experience social and economic barriers to attend screening and human papillomavirus (HPV) vaccination programs. Male support has been proven successful in uptake of other reproductive healthcare services. This qualitative study with focus groups aimed to understand the perspectives of males on cervical cancer screening and HPV vaccination in Western-Uganda This knowledge could be integrated into awareness activities to increase the attendance of cervical cancer screening and HPV vaccination programs.

Materials and methods
Focus group discussions were conducted with men aged 25 to 60 years, who were married and/or had daughters, in Kagadi district, Mid-Western Uganda. All interviews were transcribed verbatim and thematically analyzed using an inductive approach.

Results
Eleven focus group discussions were conducted with 67 men. Men were willing to support their wives for screening and their daughters for HPV vaccination. Misperceptions such as family planning and poor personal hygiene leading to cervical cancer, and misperception of the preventative aspect of screening and vaccination were common. Women with cervical cancer suffer from stigmatization and family problems due to loss of fertility, less marital sexual activity, domestic violence and decreased economic productivity.

Conclusions
Ugandan men were willing to support cervical cancer prevention for their wives and daughters after being informed about cervical cancer. Limited knowledge among men about the risk factors and causes of cervical cancer, and about the preventative aspect of HPV vaccination and screening and their respective target groups, can limit uptake of both services. Screening and vaccination programs should actively involve men in creating awareness to increase uptake and acceptance of prevention.
One single drug-coated balloon for all shapes/diameters? Neointimal proliferation inhibition in porcine peripheral arteries
Authors: Bienek Stephanie , Kusmierczuk Maciej , Schnorr Beatrix , Gemeinhardt Ole , Bettink Stephanie , Scheller Bruno 
Published: January 2023

Background
Long diseased vessel segments of peripheral arteries may display irregular shapes with different diameters. The aim of this study was to investigate inhibition of neointimal proliferation in porcine peripheral vessels with different diameters covered by one single hyper-compliant drug-coated balloon (HCDCB), compared to conventional drug-coated balloons (DCB), each selected according to the respective vessel diameter.

Methods and results
Neointimal proliferation was stimulated in proximal and distal segments of the peripheral arteries by balloon overstretch and stent implantation. Inhibition of neointimal proliferation by one single HCDCB was compared to two vessel diameter-adjusted DCB per artery and to one single uncoated hyper-compliant balloon (HCB). Sixteen HCB, 16 HCDCB, and 32 DCB were used in 16 arteries each. Quantitative angiography (QA), optical coherence tomography (OCT) and histology showed a similar anti-restenotic effect for one HCDCB compared to two vessel diameter-adjusted DCB in narrow distal and wider proximal segments (QA diameter stenosis: 18.7±12.3% vs. 22.8±15.5%, p = 0.535; OCT area stenosis: 21.4±11.6% vs. 23.6±12.3%, p = 0.850; histomorphometry diameter stenosis: 27.5±7.1% vs. 26.9±8.0%, p = 0.952) and indicated significant inhibition of neointimal proliferation by HCDCB vs. uncoated HCB (QA diameter stenosis: 18.7±12.3% vs. 30.3±16.7%, p = 0.008; OCT area stenosis: 21.4±11.6% vs. 34.7±16.0%, p = 0.004; histomorphometry diameter stenosis: 27.5±7.1% vs. 32.5±8.5%, p = 0.038).

Conclusions
HCDCB were found to be similar effective as DCB in inhibiting neointimal proliferation in vessel segments with different diameters. One single long HCDCB may allow for treatment of segments with variable diameters, and thus, replace the use of several vessel diameter-adjusted DCB.
Detection of SARS-CoV-2 infection by saliva and nasopharyngeal sampling in frontline healthcare workers: An observational cohort study
Authors: Walker Naomi F. , Byrne Rachel L. , Howard Ashleigh , Nikolaou Elissavet , Farrar Madlen , Glynn Sharon , Cheliotis Katerina S. , Cubas Atienzar Ana I. , Davies Kelly , Reiné Jesús , Rashid-Gardner Zalina , German Esther L. , Solórzano Carla , Blandamer Tess , Hitchins Lisa , Myerscough Christopher , Gessner Bradford D. , Begier Elizabeth , Collins Andrea M. , Beadsworth Mike , Todd Stacy , Hill Helen , Houlihan Catherine F. , Nastouli Eleni , Adams Emily R. , Mitsi Elena , Ferreira Daniela M. ,   on behalf of the SAFER investigators
Published: January 2023

Background
The SARS-CoV-2 pandemic has caused an unprecedented strain on healthcare systems worldwide, including the United Kingdom National Health Service (NHS). We conducted an observational cohort study of SARS-CoV-2 infection in frontline healthcare workers (HCW) working in an acute NHS Trust during the first wave of the pandemic, to answer emerging questions surrounding SARS-CoV-2 infection, diagnosis, transmission and control.

Methods
Using self-collected weekly saliva and twice weekly combined oropharyngeal/nasopharyngeal (OP/NP) samples, in addition to self-assessed symptom profiles and isolation behaviours, we retrospectively compared SARS-CoV-2 detection by RT-qPCR of saliva and OP/NP samples. We report the association with contemporaneous symptoms and isolation behaviour.

Results
Over a 12-week period from 30th March 2020, 40·0% (n = 34/85, 95% confidence interval 31·3–51·8%) HCW had evidence of SARS-CoV-2 infection by surveillance OP/NP swab and/or saliva sample. Symptoms were reported by 47·1% (n = 40) and self-isolation by 25·9% (n = 22) participants. Only 44.1% (n = 15/34) participants with SARS-CoV-2 infection reported any symptoms within 14 days of a positive result and only 29·4% (n = 10/34) reported self-isolation periods. Overall agreement between paired saliva and OP/NP swabs was 93·4% (n = 211/226 pairs) but rates of positive concordance were low. In paired samples with at least one positive result, 35·0% (n = 7/20) were positive exclusively by OP/NP swab, 40·0% (n = 8/20) exclusively by saliva and in only 25·0% (n = 5/20) were the OP/NP and saliva result both positive.

Conclusions
HCW are a potential source of SARS-CoV-2 transmission in hospitals and symptom screening will identify the minority of infections. Without routine asymptomatic SARS-CoV-2 screening, it is likely that HCW with SARS-CoV-2 infection would continue to attend work. Saliva, in addition to OP/NP swab testing, facilitated ascertainment of symptomatic and asymptomatic SARS-CoV-2 infections. Combined saliva and OP/NP swab sampling would improve detection of SARS-CoV-2 for surveillance and is recommended for a high sensitivity strategy.