bluuebunny/crossref_metadata_2025_split huggingface dataset:
Malignant Brenner tumor of ovary: A case report and review of literature
Authors: Alex Neetu Mariam , Ananthakrishnan Ramya , J Kumanan , Thirumalairaj Raja 
Published: June 2023

Abstract
Background: Brenner tumours of ovary are rare representing 1-5% of epithelial ovarian tumours. They are further categorized as benign, proliferative (borderline), or malignant. Diagnosis of Malignant Brenner requires surgical excision and histopathological examination as tumor does not possess pathognomonic imaging features. Further, histological diagnosis of malignant Brenner tumor is challenging due to overlapping morphologic and histopathological features with benign and proliferative Brenner tumours, and transitional cell carcinoma.
Case details: A 49 years old female presented with history of vague abdominal pain for 2 months. A computerized tomography scan revealed a mixed cystic and solid anterior mass with thickened septations and peripheral nodularity. She underwent Total abdominal hysterectomy and bilateral salphingo-oophorectomy. Histopathological examination and immunohistochemistry was suggestive of malignant Brenner tumor of ovary. 2 years later she presented with nodal recurrence of disease for which she was started on Gemcitabine and Cisplatin combination chemotherapy.
Conclusion: Malignant Brenner tumor has poor prognosis. The treatment approach is not well established in view of its rarity, while surgical excision of the tumour remains the constant. The real benefit of the adjuvant chemotherapy remains unclear. Treatment options for disease recurrence included gemcitabine, tamoxifen, doxorubicin, and eribulin, though disease recurred after all of these regimens
Developing a risk prediction tool for Lung Cancer in Kent and Medway, England: Cohort Study using linked Data
Authors: Howell David , Buttery Ross , Badrinath Padmanabhan , George Abraham , Hariprasad Rithvik , Vousden Ian , George Tina , Finnis Cathy 
Published: June 2023

Abstract
Background
Lung cancer has the poorest survival due to late diagnosis and there is no universal screening. Hence early detection is crucial. Our objective was to develop a lung cancer risk prediction tool at a population level.
Methods
We used a large place based linked data set from a local health system in southeast England which contained extensive information on each individual covering demographic, socioeconomic, lifestyle, health, and care service utilization. We exploited the power of Machine Learning to derive risk scores using linear regression modelling. Tens of thousands of model runs were undertaken to identify attributes which predicted the risk of lung cancer.
Results
Initially sixteen attributes were identified. A final combination of seven attributes were chosen based on the number of cancers detected which formed the Kent & Medway lung cancer risk prediction tool. This was then compared with the criteria used in the wider Targeted Lung Health Checks programme. The prediction tool outperformed by detecting 822 cases compared to 581 by the lung check programme currently in operation.
Conclusion
We have demonstrated the exceptional application and utility of Machine Learning in developing a risk score for lung cancer and discuss its clinical applicability.
Improved Search and Rescue Methodology for Locating a Missing ROV near the Titanic Site
Authors: Tifrit Abdelkrim 
Published: June 2023

Abstract
In underwater search and rescue operations, the timely and accurate location of a missing remotely operated vehicle (ROV) is crucial for successful rescue efforts. This article presents an improved methodology for enhancing the detection and recovery of a recently missing ROV near the Titanic site. The proposed approach involves the deployment of a sonar-based bomb to analyze the acoustic signals and their interactions with the ROV's echoes and the Titanic wreckage. By employing advanced signal processing techniques and collaborating with the Deep-Sea Exploration Laboratory, the aim is to expedite the search and rescue process. In this article, we present a calculation methodology to estimate the remaining oxygen supply for a submerged Remotely Operated Vehicle (ROV) after 4 days. Considering an initial oxygen supply of 1000 liters and an oxygen consumption rate of 10 liters per hour per person, we analyze the available oxygen and determine the feasibility of the ROV rescue operation. The calculations are based on the assumption of 5 individuals onboard the ROV. The results highlight the importance of timely oxygen replenishment or immediate rescue measures in such situations.
Copper sulfate and cupric citrate supplementation improves growth performance, nutrient utilization, antioxidant capacity and intestinal microbiota of broilers Cupric citrate addition on performance in broilers
Authors: Wu Xuezhuang , Zhou Yahao , Lu Zhentao , Zhang Yunting , Wen Aiyou , Zhu Mingxia , Jiang Qingkui 
Published: June 2023

Abstract
This experiment was conducted to study the effects of copper sulfate and cupric citrate on growth performance, nutrient utilization, antioxidant capacity and intestinal microbiota of broilers. A total of 360 one-day-old Ross 308 broilers were randomly divided into 5 groups with 6 replicates in each group and 15 broilers per replicate. Broilers in the control group were fed a basal diet, and animals in other four groups were fed basal diets supplemented with 2 sources (copper sulfate and cupric citrate) and 2 levels (50 and 100 mg/kg dry matter). The experiment lasted for 42 days. The results showed that dietary cupric citrate supplementation increased the average daily gain (P = 0.0313). The average daily feed intake and feed gain ratio, however, were not affected by dietary copper sulfate or cupric citrate (P > 0.10). Additionally, dietary copper sulfate or cupric citrate supplementation increased the digestibility of crude protein (P = 0.0554) and energy (P = 0.0191). For intestinal microflora, dietary cupric citrate supplementation decreased the concentration of Lactobacillus and Escherichia coli (P < 0.05) in the ileal digesta or cecal digesta. In addition, dietary Cu supplementation increased the pH in duodenum (P = 0.0008) and jejunum (P = 0.0589). The activities of serum Cu-Zn superoxide dismutase (P = 0.0899), and ceruloplasmin (P = 0.0269) were increased by Cu addition. The present study demonstrated cupric citrate fed to broilers has a positive effect on growth and nutrient utilization. Our results also show that moderately high Cu in the diet increases the pH in duodenum and jejunum, and reduced the concentration of Lactobacillus and Escherichia coli in the ileal digesta or cecal digesta.
Abnormal Frame Extraction and Object Tracking Hybrid Machine Learning
Authors: Archana Mrs Kande , Prasad V Kamakshi 
Published: June 2023

Abstract
The detection of events using the video data is getting popular due to the detailed information made available from the video data for multiple instances. This popularity is increasing the use of number of devices and amount of data generated from various sources, which makes the manual detection of abnormal events highly complex, and the recent research demands highly timely and highly accurate automation process. Thus, this work proposes a three-phase solution to address this problem as using a hybrid segmentation process for object detection with 97% accuracy, detection of the objects by using a pre-trained machine learning model with 98% accuracy and detection of the motion using predictive regression model with mean time of 58 ns. This proposed work has demonstrated benchmarking outcomes and showcases highly accurate detection process for making video-based surveillance safer and better choice.
Effect of Acupuncture for Patients with Knee Osteoarthritis: Study Protocol for a Double-dummy Randomized Controlled Trial
Authors: Yin Shuai , Chang Yiniu , Yan Xiuli , Zhang Zhenhua , Yan Xiao , Zhang Zhaoyang , Zhang Taojun , Xi Jianming , Feng Xiaodong , Wu Nan 
Published: June 2023

Abstract
Background Acupuncture has been used to relieve chronic pain in patients with knee osteoarthritis (KOA), but the evidence is contradictory. Therefore, we carefully designed a double-dummy randomized controlled trial (RCT) to explore the therapeutic effect of acupuncture for KOA.Methods/design: Total of 138 eligible participants with KOA who consent to participate will be randomly divided into groups A, B and C in a ratio of 1:1:1. Participants in group A will receive verum acupuncture and placebo gel, while those in groups B and C will be treated with Diclofenac Diethylammon gel and sham acupuncture, sham acupuncture and placebo gel respectively. The patients will receive 4 weeks of treatment, 5 times a week, including acupuncture treatment once a day for 30 minutes and gel treatment three times a day. The primary outcome will be the change of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at week 4th. The secondary outcomes will include Visual Analog Scale (VAS), Arthritis Quality of Life Measurement Scale Simplified Scale (AIMS2-SF), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI) and Credibility/Expectancy Questionnaire. The evaluation will be performed at baseline, week 4th, 8th and 12th after randomization.Discussion This double-dummy RCT used Diclofenac Diethylammon gel as a positive control, and the completion of this trial will provide detailed and accurate evidence of the efficacy and safety of acupuncture for KOA.Trial registration: China Clinical Trials Registry No.ChiCTR2100043947. Registered on September 24, 2020.https://www.chictr.org.cn/showproj.html?proj=122536
Tailoring the intrinsic magneto-electronic, mechanical, thermo- physical and thermoelectric response of Cobalt-based Heusler material: an ab-initio insight
Authors: Gurunani Bharti , Gupta Dinesh C. 
Published: June 2023

Abstract
We have calculated the fundamental properties of CoHfSi and CoHfGe half-Heusler alloys within the density functional theory simulation scheme as embedded in Wien2k. First and foremost, the structural optimization signifies that both the alloys suitably crystallize in cubic C1b structure with Y1 as a dominant ferromagnetic phase. The electronic properties have been computed within the applied approximation schemes like Generalized Gradient Approximation and modified Becke-Johnson potential. The electronic properties of these half-Heusler exhibit a half-metallic character, which is additionally substantiated by the presence of an integer value of the magnetic moment. Further, the investigation of different thermodynamic parameters by utilization of the quasi-harmonic Debye model to examine the thermodynamic stability of alloys at various temperatures and pressure (0K to 900K and 0 GPa to 20 GPa). The Seebeck coefficients, electrical conductivity, thermal conductivity and power factor are scrutinized to comprehend the thermoelectric properties. The collected results indicate that these alloys are applicable for spintronic and thermoelectric.
Spatio-temporal Changes and Attribution of Vegetation in the Jungar Banner of Inner Mongolia During 2010 to 2022
Authors: Wang Xiaowen , Ji Jinzhu , Xue Xinlei , Li Huaibin 
Published: June 2023

Abstract
Fractional vegetation cover (FVC) is an important feature of the ecosystem, which reflects the ecological degeneration and restoration in the semi-arid areas. In this study, the spatio-temporal FVC changes were quantitatively evaluated from 2010 to 2022 in Jungar Banner of Inner Mongolia, China. Theil-Sen slope estimator and Mann-Kendall algorithm were used to monitor the spatio-temporal change trend of the FVC. Then, Hurst exponent and Theil-Sen Slope were integrated to evaluate the consistency of FVC change and predict its spatiotemporal evolution trend. Finally, we used correlation analysis to determine the association between FVC and other factors, such as terrain, temperature and precipitation. These results demonstrated that the condition of FVC in the Jungar Banner is good which was predominated by medium-low and medium FVC. The area with increasing FVC was little smaller than that with decreased FVC, but the decreased area was mainly dominated by no significant decrease. However, the Kubuqi Dessert, Yellow River, Loess plateau and mining areas accounted for the majority of the degraded areas. At present, the 42.7% of Jungar Banner appeared improved in the FVC, while the 57.3% appeared the degradation in the FVC, but the area of degradation was mainly slightly degraded in the future. In addition, the terrain and mining activity in Jungar Banner had a significant impact on the spatio-temporal distribution of FVC. This work will provide basic data and information for the future ecological development of Jungar Banner.
A Case Report on Damage to School Buildings During the 2015 Nepal Earthquake and Reconstruction Strategy
Authors: Paudyal Youb Raj , Bhandary Netra Prakash 
Published: June 2023

Abstract
The 2015 Nepal Earthquake (Mw7.8) affected more than 9,000 schools in the country. Damage distribution in the 14 most-affected administrative districts shows that the construction practices were an important determent for the level of damage extended. Use of improper construction materials, lack of construction supervision, and non-compliance with the existing building codes during design and construction probably contributed to the severe damage of most of the school buildings. Preliminary damage assessment results show that in the most-affected districts, about 86% schools were affected by the earthquake and about one million students were out of their schools for a long time. The damage survey data indicate that about 30% classrooms collapsed, about 13% classrooms sustained major damage, and about 17% classrooms sustained minor damage within the 14 districts. Such evidence of loss and damage in the earthquake disasters provides an opportunity to learn lessons for the future preparedness and to encounter the disaster challenges. Based on the damage analysis data and experience of reconstruction process after the 2015 Nepal Earthquake, this paper highlights the steps to be considered during reconstruction strategy planning for school buildings after an earthquake disaster.
The Effect of Gamified Depth on Malaysian Higher Education Students’ Intrinsic Motivation Level and Achievement Level
Authors: Yie Darren Lim , Sanmugam Mageswaran , Yahaya Wan Ahmad Jaafar Wan , Khlaif Zuheir N. 
Published: June 2023

Abstract
Gamification, which is the implementation of game elements in non-game situations such as the educational sector, has received its popularity in recent years due to its positive impact on the teaching and learning process. The manipulative nature of gamification is often criticized as it traps students in a reward loop, diminishing the positive effect as time elapses. However, major studies ignored the depth of gamification and thus, the purpose of the study is to identify the effect of gamified depth on students’ intrinsic motivation and performance levels. This study uses a quasi-experimental approach that involves a total of 117 undergraduate students separated into control (n=57) and experimental (n=60) groups. Then they are exposed to two gamified platforms, Kahoot! for shallow gamification and Classcraftfor deep gamification respectively throughout 4 weeks. The study utilizes the Intrinsic Motivation Inventory (IMI) to measure the changes that occur within students’ intrinsic motivation level over the study and an achievement test is given at the final lesson. T-tests and regression analysis were used to test the hypothesis of this study. The results showed that deep gamification does increase learners’ intrinsic motivation level, but shallow gamification decreases. Anyhow, students who use the shallow gamified learning environment have a higher performance than those in a deep gamified environment. Students’ language mastery, interest, attitude, and familiarity with technology are presumed to affect the outcome of the studies. Distinct subjects and age groups are recommended for future studies to develop a proper gamified depth framework in the educational sector.
Remote metastasis detection by video thermometry: A promissing preclinical study
Authors: Cabral Paula Gebe Abreu , Cadena Silvia Marcela Ruiz , Santos Scarlath Ohana Penna dos , de Souza Sávio Bastos , Alves José Edgard De Oliveira , Scheffer Jussara Peters , Leandro Hassan Jerdy , Braga Gustavo D'annunciação , Silva Renato Martins da , Arruda Raul Ferraz , Cabral Sheila Passos de Figueiredo , Antunes Fernanda , Oliveira André Lacerda de Abreu 
Published: June 2023

Abstract
The thermometric video image (VTM) can guide the search for distant metastases, once the vascular architecture is known, identifying, by segmentation, the tumor thermal impression and a similar pattern at a distance. Thus, suspicious areas can be better investigated, improving the postoperative prognosis. In this study, it was possible to observe the assertive capacity of video thermometry in identifying distant metastases and breast tumors in female dogs, not palpable or visible to the naked eye, in relation to conventionally used techniques. It was also possible to identify textures with anatomical limits, from emboli to early formations of carcinomas, adenocarcinomas and adenomyoepithelioma. It was also possible to find non-neoplastic changes such as dermatitis, lipoma, hyperplasia and breast cysts. it can be concluded that the video thermometry (VTM) technique was capable of identifying distant metastases from the primary tumor and other benign alterations with great precision. However, for this to be possible, it is essential that the processing be carried out by SaMD (Software as a Medical Device), with tools capable of identifying patterns and thermal signatures, just like the algorithm, thus increasing the efficacy of the technique.
Quality index method to evaluate the quality of Jinga shrimp (<i>Metapenaeus affinis</i> L.) preserved in ice water
Authors: Hien Bui Thi Thu , Pham Diem Thi , Vu Lan Phuong , Dao Phuong Hoa , Tuyen Pham Van , Nghia Nguyen Viet , Bat Nguyen Khac 
Published: June 2023

The Quality Index Method (QIM) provides a quick and accurate quality assessment. It makes it possible to calculate preserving time and establish the freshness of sea food. This article introduces a quality assessment program based on the QIM scheme and quality index (QI) for the Jinga shrimp.
The research included Jinga shrimps (Metapenaeus affinis L.), a commercially valuable aquatic species widely distributed throughout the Vietnamese coast. The input data included the changes in appearance and sensory profile of sampled shrimps during 20 days of storage at 0–4°C in ice water.
They were used to construct a QIM scale, which was applied to other shrimp samples at different storage time to evaluate the relationship between the QI score and the storage time. After that, the QIM scale was tested on ten random shrimp samples to verify its shelf-life predictive power. This study managed to establish a correlation equation between the QI scores and the storage time with the coefficient of R2= 0.97. This correlation proved highly reliable as verified by comparing the predicted and actual best shelf life of Jinga shrimps stored in ice water for 8–10 days.
The QIM program provides a practical and effective science-based tool that delivers fast and reliable results for customers, fishermen, food traders, and aquacultural enterprises.
Predictors of pre-and post-care handwashing among community healthcare providers: a cross-sectional survey in Bangladeshi community clinics
Authors: Hsan Kamrul , Mubarak Mahfuza , Rahman Tareq , Siddique Abu Bakkar , Rahman Mohammad Azizur , Gozal David , Kameli Md. Marjad Mir , Awal Nurullah , Hossain Md. Mahfuz 
Published: June 2023

Abstract
Lack of proper handwashing by healthcare providers is the major vector for the spread of nosocomial pathogens in healthcare settings. A cross-sectional study was conducted among 128 community healthcare providers (CHCPs) in the Kurigram district of Bangladesh to investigate predictors of handwashing before and after clinical care encounters. Data were collected between November and December 2019 via a paper-and-pen based survey using a semi-structured questionnaire. CHCP's pre-care handwashing with soap/antiseptic hand cleaner was predicted by a higher level of education (Unadjusted/Crude odds ratio (COR) = 7.16, 95% CI 2.39–21.40, p = 0.000 and COR = 9.58, 95% Confidence Interval (CI) 3.28–27.92, p = 0.000, bachelors and masters, respectively), lengthier service (COR = 6.90, 95% CI 1.40–34.17, p = 0.015 and COR = 7.8, 95% CI 1.49–40.98, p = 0.015, 5–8 and &gt;8 years, respectively), and presence of handwashing facility (COR = 4.48, 95% CI 1.34–14.95, p = 0.015). However, post-care handwashing was also associated with a higher level of education (COR = 13.36, 95% CI 1.54–115.63, p = 0.019, masters) and availability of soap (COR = 17.73, 95% CI 5.03–59.73, p = 0.000), as well as by male sex (COR = 3.14, 95% CI 1.01–9.79, p = 0.049). Implementation of an effective training program on hand hygiene combined with improved access to handwashing stations and adequate supply of soap or antiseptic hand cleaner is required to improve both pre-and post-care clinical encounter handwashing practices among CHCPs.
Characteristics of the temporal and spatial evolution of rainfall under the influence of urbanization: a case study of the Beijing–Tianjin–Hebei region
Authors: Xu Chengcheng , Wang Yanzhen , Xiao Baiqing , Sun Qingyan , Lu Chuiyu , Wu Chu 
Published: June 2023

Abstract

With rapid urbanization in recent years, the frequency of extreme rainfall events has increased in major cities around the world during the flood season, and the social and economic losses caused by heavy rainfall are becoming increasingly serious. The results show that (1) the overall duration of rainfall exhibits a downward trend, and the overall spatial performance gradually decreases from east to west. (2) The mountainous areas are prone to light and moderate rainfall events; the plains are more prone to rainfall events at levels above moderate rain, especially rainstorms and heavy rain events; the probability of light and moderate rainfall events in the suburbs is close to that of the urban areas, but the probability of rainfall events at levels above heavy rain is less than that of the urban areas; the probability of rainfall events of all levels in the outer suburbs is higher. (3) Increase in rainfall in urban areas compared to the southern suburbs is greater. (4) With increasing urbanization, the built environment in the mountainous areas and plains has continued to grow, and the original underlying surface conditions have changed.
Chế tạo thiết bị vi lỏng trên nền giấy bằng máy in laser
Authors: Ngô Bảo Chân , Dương Thị Hồng Nhung , Huỳnh Huỳnh Anh Thi , Đỗ Châu Minh Vĩnh Thọ 
Published: June 2023

Thiết bị vi lỏng trên nền giấy (μPAD) mang lại bước đột phá trong phân tích mẫu nhanh và phân tích tại hiện trường. Đây là lần đầu tiên có nghiên cứu sử dụng loại mực CF279A trong chế tạo thiết bị μPAD, điều này giúp mở rộng phạm vi cũng như cung cấp các bằng chứng vào số lượng ít các nghiên cứu chế tạo thiết bị μPAD bằng máy in laser. Giấy lọc 102 được sử dụng, sau khi in bằng máy in laser, khuôn sẽ được gia nhiệt ở tủ sấy với nhiệt độ 150ºC để hình thành các vùng ưa nước và kỵ nước. Thiết bị μPAD chế tạo có độ rộng kênh kỵ nước và ưa nước lần lượt là 1,0 mm và 0,4 mm trở lên. So với một số nghiên cứu bằng các phương pháp khác như in đóng dấu, in bàn thủ công cho độ phân giải cao hơn