bluuebunny/crossref_metadata_2025_split huggingface dataset:
Matrix Metallopeptidase 9 Promotes Contraction in Human Uterine Myometrium
Authors: Ulrich Craig C. , Parker Lauren L. , Lambert Janet A. , Baldwin Lexa , Buxton Iain L. O. , Etezadi-Amoli Neda , Leblanc Normand , Burkin Heather R. 
Published: January 2025

Abstract
Matrix metallopeptidase 9 (MMP9) is a secreted zinc-dependent peptidase known for extracellular remodeling. MMP9 is elevated in tissues from women experiencing preterm labor, and previous research has shown that the addition of combined matrix metallopeptidases 2 and 9 (MMP2/9) enhances uterine contractions. We hypothesized that adding MMP9 alone would enhance myometrial contractions and that specific MMP9 inhibition would suppress uterine contractions. In myometrial tissue from women undergoing term Caesarean sections, we observed an increased contractile response as measured by area under the curve over time in tissues treated with MMP9 compared to vehicle-treated controls (p = 0.0003). This effect was primarily due to increased contraction frequency in MMP9-treated tissues compared to controls (p < 0.0001). Specific inhibition of MMP9 with the highly selective MMP9 inhibitor 1 (AG-L-66085) reduced contractile responses in myometrial tissues from pregnant women. We observed a reduction in the oxytocin-induced contractile response as measured by area under the curve over time (p < 0.0001) and contraction amplitude (p < 0.0068) in AG-L-66085-treated tissues compared to vehicle-treated controls. To determine the effects of MMP9 inhibition in the absence of exogenous oxytocin, we tested the effects of AG-L-66085 on spontaneous contractions. The area under the curve (p = 0.0415) and amplitude (p = 0.0354) of spontaneous contractions were reduced in response to 1 μM AG-L-66085, and the inhibitory effects increased as the AG-L-66085 concentration increased. Together, these data support the hypothesis that elevated MMP9 promotes myometrial contractions and labor, while its inhibition promotes relaxation.
Contribution of ground motions to landslide distribution during the 2018 Hokkaido Eastern Iburi earthquake
Authors: Huang Dongliang , Goto Hiroyuki , Xiang Chenlin , Zhao Lianheng , Zhang Yingbin 
Published: January 2025

AbstractEarthquake-induced landslides often have unique regional distribution characteristics and cause significant damage to the natural environment and severe loss of life and property. The aim of this study is to comprehensively investigate the contribution of ground motion time histories to the unique landslide distribution of the 2018 Hokkaido Eastern Iburi earthquake: although the geological and geomorphological conditions are similar on the northern and southern sides of the epicenter, the landslide density is obviously greater on the northern side. Overall, the synthetic waveforms in the near-source area are generated using a distance-weighted spatial interpolation method and a spectrum-matching technique, and dynamic finite difference simulations are then employed to further reproduce the actual landslide distribution pattern. The workflow contains two steps. First, the seismic ground motions in the near-source area are spatially evaluated by combining the ground motion model and the phase characteristics extracted from the downhole records. Then, dynamic analysis of slope stability using synthetic waveforms is conducted to form landslide susceptibility maps. As a result, the actual spatial pattern in which landslide density is greater on the northern side of the epicenter is reproduced and explained successfully. Differences in phase components are found to be responsible for the different deformation processes of slopes under seismic loading. The proposed method in this study can be applied to risk analysis of regional landslide hazards in regard to future earthquakes.
Forecasting Arctic sea-ice drift: insights from two case studies
Authors: Välisuo Ilona , Tietsche Steffen 
Published: January 2025

Abstract
The two main large-scale features of Arctic sea-ice drift are the Beaufort Gyre and the Transpolar Drift Stream. They exhibit strong intraseasonal and interannual variability. Winter 2016/17 showed increased cyclone activity, leading to the collapse of the Beaufort Sea high and the reversal of the Beaufort Gyre. Winter 2020/21 displayed decreased cyclone activity and intense anticyclonic ice transport in the Beaufort Gyre. Here we show that the European Centre for Medium-Range Weather Forecasts’s (ECMWF) extended-range (46 days) retrospective forecasts were able to predict the ice motion during these cases. The initial contrasts in sea level pressure, surface winds and ice drift were well captured, and their temporal evolution—including the reversal of the usual drift direction—well reproduced by the forecasts initialized about a week before the event. Sea-ice thickness in the forecast exhibited initial errors even greater than 1 m that persisted throughout the forecast and negatively affected the ice speed forecast. Despite these shortcomings, the dynamic forecast outperformed the persistence and climatology forecast and represented the observed relation between surface winds and ice drift well. The benefit of dynamic forecasts is especially clear in cases that differ from climatology, like the one we focus on.
AI product cards: a framework for code-bound formal documentation cards in the public administration
Authors: Celepija Albana , Palmero Aprosio Alessio , Lepri Bruno , Kazhamiakin Raman 
Published: January 2025

Abstract
Currently, artificial intelligence (AI) is integrated across various segments of the public sector, in a scattered and fragmented manner, aiming to enhance the quality of people’s lives. While AI adoption has proven to have a great impact, there are several aspects that hamper its utilization in public administration. Therefore, a large set of initiatives is designed to play a pivotal role in promoting the adoption of reliable AI, including documentation as a key driver. The AI community has been proactively recommending a variety of initiatives aimed at promoting the adoption of documentation practices. While currently proposed AI documentation artifacts play a crucial role in increasing the transparency and accountability of various facts about AI systems, we propose a code-bound declarative documentation framework that aims to support the responsible deployment of AI-based solutions. Our proposed framework aims to address the need to shift the focus from data and models being considered in isolation to the reuse of AI solutions as a whole. By introducing a formalized approach to describing adaptation and optimization techniques, we aim to enhance existing documentation alternatives. Furthermore, its utilization in the public administration aims to foster the rapid adoption of AI-based applications due to the open access to common use cases in the public sector. We further showcase our proposal with a public sector-specific use case, such as a legal text classification task, and demonstrate how the AI Product Card enables its reuse through the interactions of the formal documentation specifications with the modular code references.
COVID-19: An exploration of consecutive systemic barriers to pathogen-related data sharing during a pandemic
Authors: Yehudi Yo , Hughes-Noehrer Lukas , Goble Carole , Jay Caroline 
Published: January 2025

Abstract
In 2020, the COVID-19 pandemic resulted in a rapid response from governments and researchers worldwide, but information-sharing mechanisms were variable, and many early efforts were insufficient for the purpose. We interviewed fifteen data professionals located around the world, working with COVID-19-relevant data types in semi-structured interviews. Interviews covered both challenges and positive experiences with data in multiple domains and formats, including medical records, social deprivation, hospital bed capacity, and mobility data. We analyze this qualitative corpus of experiences for content and themes and identify four sequential barriers a researcher may encounter. These are: (1) Knowing data exists, (2) being able to access that data, (3) data quality, and (4) ability to share data onwards. A fifth barrier, (5) human throughput capacity, is present throughout all four stages. Examples of these barriers range from challenges faced by single individuals to non-existent records of historic mingling/social distance laws, and up to systemic geopolitical data suppression. Finally, we recommend that governments and local authorities explicitly create machine-readable temporal “law as code” for changes in laws such as mobility/mingling laws and changes in geographical regions.
Overruling the Executive: Judicial Strategies to Resist Democratic Erosion
Authors: Garcia-Holgado Benjamin 
Published: January 2025

Abstract
How can autonomous apex courts with specific attitudes and role conceptions counter executive aggrandizement? This article theorizes two causal mechanisms through which justices can resist democratic erosion. The first mechanism involves apex courts employing judicial review to neutralize autocratic legalism by blocking strategies such as institutional conversion, replacement, and layering that executives use to expand their power. The second involves apex courts building coalitions within and beyond the judiciary, enabling diverse actors – including judges, political parties, the media, and NGOs – to leverage their unique resources against executive encroachment. I conceptualize these two mechanisms by combining theory-building process tracing with counterfactual analysis of an unlikely case of democratic resilience: Argentina from 2007 to 2015. Drawing on evidence from 125 elite interviews, over a thousand newspaper articles, hundreds of state documents, memoirs, and other primary sources, this article demonstrates how the Supreme Court nullified President Cristina Kirchner’s attempts to undermine freedom of expression and judicial independence, thereby contributing to democratic resilience.
Against Hope Labour in the Public Humanities
Authors: Paris Jamie 
Published: January 2025

Abstract
This article argues that the number of tenure-line academic positions has been shrinking for decades, and that non-tenure track workers are being asked to do more un- and under-compensated publishing, editing, and peer review labour this labour. This is all having a detrimental impact on larger, public humanities based projects. Often, non-tenure track faculty are paid for their hard earned expertise in a currency of hope, or in the implicit promise of future opportunities. Large public humanities programs, should resist the temptation to use hope labour and gig workers.
Probing the production of quantum technologies to imagine its legal framework
Authors: Mittal Anushka 
Published: January 2025

Abstract
Quantum technologies (QT) are being awaited with excitement. They are supported by many governments, the corporate sector, international bodies and technology forecasters. There is discursive investment as well in terms of creating expectations and laying down a vision for the ‘Second Quantum Revolution’. Science and technology studies are also playing their part to think of the quantum future along with philosophical discussions around it. These visions and expectations perform an implicit and latent function of steering policy proposals and governance. At the current stage of development of quantum technologies, a comprehensive and cogent legal framework is hard to envisage. As it is difficult to foresee the final shape of these technologies, a way to proceed can be to focus on the legal enquiry related to economic, political and policy factors which contribute to its material emergence. This can broaden the focus from thinking about its impact to contextualizing its production and development. Further, it allows a way of determining the extent to which social science and ethical frames can apply to the governance of QT, given the legal and practical realities of technology production and use. This article maps the myriad governance frameworks being envisaged to think about the future of QT. It zooms onto the discussion related to the access divide being framed for QT to understand the points of legal intervention. It uses the case of quantum computing to understand the way legal and practical policy solutions have been ideated. It highlights the way these solutions entrench power of digital infrastructure providers further. This seeks to motivate further work to expand the scope of a legal framework for QT.
La surveillance : un instrument d’évitement de l'intrusion militaire dans le champ politique camerounais
Authors: Dongmo Julio César 
Published: January 2025

Résumé
Dans la littérature existante, les auteurs associent l'absence et la non-récurrence des intrusions militaires dans le champ politique à la peur des sanctions d'un éventuel échec, à des nominations militaires sélectives sur la base identitaire, à la mise en place de contrepoids militaires, à l'institutionnalisation d'un régime de privilèges militaires et au sens de professionnalisme de l'armée. Partant du postulat que les militaires sont des acteurs rationnels dont la loyauté et la fidélité peuvent évoluer en fonction des conjonctures et des « fenêtres d'opportunités » qui se présentent à eux, cet article montre que ces facteurs ont un pouvoir explicatif limité et soutient qu'une surveillance efficace – aussi bien des militaires que des acteurs sociopolitiques qui peuvent leur donner un prétexte d'intrusion dans le champ politique – est le facteur déterminant. Au-delà de la non-occurrence du coup d’État, cette explication contribue à la littérature sur les stratégies de survie autoritaire. Cette littérature met un accent exclusif sur la répression, la cooptation et la légitimation ; or, la surveillance s'entremêle avec ces stratégies, et ce sont leurs effets combinés qui créent les conditions de la persistance autoritaire.
Our lives go better in a world created by God
Authors: Ballard Brian 
Published: January 2025

Abstract
This article develops a novel argument that God’s existence would greatly increase our prospects for meaning in life. The key idea is that if God exists, He stands in certain relations to the world that would confer value upon it. For instance, God would be its creator and sustainer. The world would thus gain value in much the way that relics gain value by their links with historical persons and events. And crucially, as a result of this infusion of value, our lives go better because the things we engage with matter more.
Enhancing trajectory-tracking accuracy of high-acceleration parallel robots by predicting compliant displacements
Authors: Paksoy Erkan , Dede Mehmet İsmet Can , Kiper Gökhan 
Published: January 2025

Abstract
For precision-required robot operations, the robot’s positioning accuracy, repeatability, and stiffness characteristics should be considered. If the mechanism has the desired repeatability performance, a kinematic calibration process can enhance the positioning accuracy. However, for robot operations where high accelerations are needed, the compliance characteristics of the mechanism affect the trajectory-tracking accuracy adversely. In this paper, a novel approach is proposed to enhance the trajectory-tracking accuracy of a robot operating at high accelerations by predicting the compliant displacements when there is no physical contact of the robot with its environment. Also, this case study compares the trajectory-tracking characteristics of an over-constrained and a normal-constrained 2-degrees-of-freedom (DoF) planar parallel mechanism during high-acceleration operations up to 5 g accelerations. In addition, the influence of the end-effector’s center of mass (CoM) position along the normal of the plane is investigated in terms of its effects on the proposed trajectory-enhancing algorithm.
The economic importance and mobility of horses in the Roman Netherlands
Authors: Groot Maaike , Gerling Claudia , Pike Alistair W. G. 
Published: January 2025

Abstract
Previous research has suggested that horse breeding, with the army as the intended buyer, was an important part of the local agrarian economy in the Roman Dutch eastern river area. Since it is very difficult to trace the origins of horses by traditional archaeozoological methods, strontium isotope analysis was used to investigate the origins of horses in both military and rural sites. These new data are integrated with data on horse frequencies and size to assess the economic importance of horses in rural communities in the eastern river area and further investigate possible supply networks. Both horse frequencies and horse size increase from the Early Roman period onwards, reflecting the significant economic importance of horses in this region. The laser ablation 87Sr/86Sr ratios show evidence for mobility in military horses but not in rural horses.
Exploring genetic diversity of pummelo (Citrus grandis L. Osbeck) genotypes in Devanahalli region of Karnataka, India
Authors: Koti Shivanand , Swamy G. S. K. , Ugalat Jayashree , Rao Venkat , Jayappa J. , Ainapur Shivanand D. , Kore Deepak S. , Vipin K. 
Published: January 2025

Abstract
Pummelo is the largest citrus species in the Rutaceae family and is important for human health and nutrition. This fruit is underutilized and threatened by human activities in its natural habitat. The present research was conducted in the Devanahalli region of Karnataka, which has a vast diversity of pummelo. This study aimed to evaluate 40 pummelo genotypes, selected through a preliminary survey, using morphological, biochemical and sensory assessments. Fruit and pulp weights ranged from 344.03 to 1746.23 g and 194.39 to 1073.07 g, with mean values of 939.67 and 522.81 g, respectively. Traits such as fruit length, diameter, fruit axis diameter, fruit volume, number of segments, rind thickness, fruit, pulp, peel weight, seed weight and seeds per fruit showed highly significant differences. Biochemical analysis revealed that ascorbic acid content varied from 28.53 to 60 mg/100 g, titratable acidity from 0.73 to 2.07% and total soluble solids from 7.63 to 11.07°Brix. High phenol (55.08–166.17 mg GAE/g FW) and flavonoid (39.26–137.78 mg CE/g FW) content were observed in fruit pulp, indicating significant antioxidant potential. Several morphological and biochemical traits exhibited significant positive correlations. A slightly higher phenotypic coefficient of variation was found for all the characters compared to the corresponding genotypic coefficient of variation. The principal component analysis indicated that the first nine components contributed 94.24% of the total variation. Hierarchical cluster analysis divided the populations into two distinct clusters. Sensory analysis indicated that genotypes, DVP-1 and DVP-2 had higher acceptability rates. The significant variations in plant traits among the genotypes offer great chances to select the best ones for genetic improvement programmes.
A Look Back At 20 Years of Research on Gender and Voting in Politics & Gender
Authors: Cassese Erin C. , Friesen Amanda 
Published: January 2025

Abstract
This essay highlights the impact of Politics & Gender on the discipline’s understanding of how gender shapes the preferences, behavior, and motivations of voters. It provides descriptive information about the prevalence of research on gender and voting in the journal, along with the proportion of articles dedicated to women voters across different regions globally. The bulk of the essay focuses on the substance of this research — drawing out major themes and identifying significant contributions within each theme — and it concludes by offering a future research agenda on gender and voting.
Weather and glufosinate efficacy; a retrospective analysis looking forward to the changing climate
Authors: Landau Christopher , Bradley Kevin , Burns Erin , DeWerff Ryan , Dobbels Anthony , Essman Alyssa , Flessner Michael , Gage Karla , Hager Aaron , Jhala Amit , Johnson Paul O , Johnson William , Lancaster Sarah , Lingenfelter Dwight , Loux Mark , Miller Eric , Owen Micheal , Sarangi Debalin , Sikkema Peter , Sprague Christy , VanGessel Mark , Werle Rodrigo , Young Bryan , Williams Martin 
Published: January 2025

Abstract
Foliar-applied postemergence applications of glufosinate are often applied to glufosinate-resistant crops to provide nonselective weed control without significant crop injury. Rainfall, air temperature, solar radiation, and relative humidity near the time of application have been reported to affect glufosinate efficacy. However, previous research may have not captured the full range of weather variability to which glufosinate may be exposed to prior to or following application. Additionally, climate models suggest more extreme weather will become the norm, further expanding this weather range glufosinate can be exposed to. The objective of this research was to quantify the probability of successful weed control (efficacy ≥85%) with glufosinate applied to some key weed species across a broad range of weather conditions. A database of >10,000 North American herbicide evaluation trials was used in this study. The database was filtered to include treatments with a single POST application of glufosinate applied to waterhemp (Amaranthus tuburculatus (Moq.) J. D. Sauer), morningglory species (Ipomoea spp.), and/or giant foxtail (Setaria faberi Herm.) <15cm in height. These species were chosen because they are well represented in the database and listed as common and troublesome weed species in both corn (Zea mays L.) and soybean [Glycine max (L.) Merr.] (Van Wychen 2020, 2022). Individual random forest models were created. Low rainfall (≤20 mm) over the five days prior to glufosinate application was detrimental to the probability of successful control of A. tuburculatus and S. faberi. Lower relative humidity (≤70%) and solar radiation (≤23 MJ m-1 day-1) the day of application reduced the probability of successful weed control in most cases. Additionally, the probability of successful control decreased for all species when average air temperature over the first five days after application was ≤25C. As climate continues to change and become more variable, the risk of unacceptable control of several common species with glufosinate is likely to increase.