bluuebunny/crossref_metadata_2025_split huggingface dataset:
Larval cisco and lake whitefish exhibit high distributional overlap within nursery areas
Authors: Brown Taylor A. , Rudstam Lars G. , Holden Jeremy P. , Weidel Brian C. , Ackiss Amanda S. , Ropp Ann J. , Chalupnicki Marc A. , McKenna James E. , Sethi Suresh A. 
Published: May 2023

AbstractCoregonine fishes, including lake whitefish (Coregonus clupeaformis) and cisco (C. artedi), are socioecologically important in the Laurentian Great Lakes and of conservation concern, but the processes driving recruitment variability are unclear. In Lake Ontario, cisco and lake whitefish exhibit similar spawning behaviours and early life histories, but population trajectories are diverging. One hypothesis is that sympatric cisco and lake whitefish larvae occupy distinct habitats and experience dissimilar local environmental conditions, despite co‐occurrence within nursery areas. We described the spatiotemporal distributions of larval cisco and lake whitefish among multiple Lake Ontario embayment nursery areas, characterised physical habitat features associated with their distributions, determined the degree of spatial habitat partitioning between species and evaluated how habitat niche divergence occurred along an ontogenetic progression. Both species were widely distributed across larval nursery areas, though lake whitefish were less abundant and more narrowly distributed than cisco. Within the yolk sac stage, lake whitefish occupied more nearshore, shallower and colder waters than cisco, indicating potential habitat niche partitioning between congeners. However, distributional differences were subtle and likely driven by differential hatch timing and staggered ontogenetic habitat shifts. Combined, our results illustrate similar habitat use between cisco and lake whitefish through the larval stage and demonstrate that ontogeny and species‐specific phenology influence habitat use for these species. This study provides additional evidence that the early life histories of cisco and lake whitefish are highly similar and does not support the hypothesis that larval habitat use differences are a major driver of differential recruitment success for these species.
Unfavorable cerebral venous outflow is associated with futile recanalization in acute ischemic stroke patients
Authors: Heitkamp Christian , Winkelmeier Laurens , Heit Jeremy J. , Albers Gregory W. , Lansberg Maarten G. , Wintermark Max , Broocks Gabriel , van Horn Noel , Kniep Helge C. , Sporns Peter B. , Zeleňák Kamil , Fiehler Jens , Faizy Tobias D. 
Published: May 2023

AbstractBackground and purposeMechanical thrombectomy (MT) has proven to be the standard of care for patients with acute ischemic stroke due to large vessel occlusion (AIS‐LVO). However, high revascularization rates do not necessarily result in favorable functional outcomes. We aimed to investigate imaging biomarkers associated with futile recanalization, defined as unfavorable functional outcome despite successful recanalization in AIS‐LVO patients.MethodsA retrospective multicenter cohort study was made of AIS‐LVO patients treated by MT. Successful recanalization was defined as modified Thrombolysis in Cerebral Infarction score of 2b–3. A modified Rankin Scale score of 3–6 at 90 days was defined as unfavorable functional outcome. Cortical Vein Opacification Score (COVES) was used to assess venous outflow (VO), and the Tan scale was utilized to determine pial arterial collaterals on admission computed tomography angiography (CTA). Unfavorable VO was defined as COVES ≤ 2. Multivariable regression analysis was performed to investigate vascular imaging factors associated with futile recanalization.ResultsAmong 539 patients in whom successful recanalization was achieved, unfavorable functional outcome was observed in 59% of patients. Fifty‐eight percent of patients had unfavorable VO, and 31% exhibited poor pial arterial collaterals. In multivariable regression, unfavorable VO was a strong predictor (adjusted odds ratio = 4.79, 95% confidence interval = 2.48–9.23) of unfavorable functional outcome despite successful recanalization.ConclusionsWe observe that unfavorable VO on admission CTA is a strong predictor of unfavorable functional outcomes despite successful vessel recanalization in AIS‐LVO patients. Assessment of VO profiles could help as a pretreatment imaging biomarker to determine patients at risk for futile recanalization.
Affordability of newer antiseizure medications in Asian resource‐limited countries
Authors: Fong Si‐Lei , Thuy Le Minh‐An , Lim Kheng‐Seang , Khosama Herlyani , Ohnmar Ohnmar , Savath Say , Mogal Zarine , Cabral‐Lim Leonor , Hung Stefanie Kar‐Yan , Asranna Ajay , Hussain Mohammad Enayet , Ng Chiu‐Wan , Tan Chong‐Tin 
Published: May 2023

AbstractObjectiveOne of the objectives of the Intersectoral Global Action Plan on epilepsy and other neurological disorders for 2022 to 2031 is to ensure at least 80% of people with epilepsy (PWE) will have access to appropriate, affordable, and safe antiseizure medications (ASMs) by 2031. However, ASM affordability is a significant issue in low‐ and middle‐income countries, preventing PWE from accessing optimal treatment. This study aimed to determine the affordability of the newer (second and third generation) ASMs in resource‐limited countries in Asia.MethodsWe conducted a cross‐sectional survey by contacting country representatives in lower‐middle‐income countries (LMICs) in Asia, including Indonesia, Lao People's Democratic Republic (PDR), Myanmar, Philippines, Vietnam, India, Bangladesh, and Pakistan, and the upper‐middle‐income country Malaysia, from March 2022 to April 2022. The affordability of each ASM was calculated by dividing the 30‐day ASM cost by the daily wage of the lowest paid unskilled laborers. Treatment costing 1 day's wage or less for a 30‐day supply of chronic disease is considered affordable.ResultsEight LMICs and one upper‐middle‐income country were included in this study. Lao PDR had no newer ASM, and Vietnam had only three newer ASMs. The most frequently available ASMs were levetiracetam, topiramate, and lamotrigine, and the least frequently available was lacosamide. The majority of the newer ASMs were unaffordable, with the median number of days' wages for a 30‐day supply ranging from 5.6 to 14.8 days.SignificanceAll new generation ASMs, whether original or generic brands, were unaffordable in most Asian LMICs.
Reflective functioning and emotion socialization behaviors in caregivers of preschoolers
Authors: Yule Kristen , Grych John 
Published: May 2023

AbstractObjectiveThe present study assessed the associations between caregivers' adverse experiences with childhood caregivers, adult and parental reflective functioning (RF), and emotion socialization strategies with their preschoolers in an effort to illuminate the unique and joint contribution of adult and parental RF in caregiving.BackgroundParental RF is defined as parents' ability to reflect on their child's state of mind, whereas adult RF involves parents' capacity to reflect on their own experiences with childhood caregivers. Most research on adult and parental RF has examined these constructs separately, making it unclear whether adult and parental RF play similar or different roles in caregiving.MethodParticipants were 64 preschooler–caregiver dyads from Head Start programs (Mchildage = 4; 81% Black). A multimethod approach was used, including self‐report, interview, and observational measures. Hierarchical linear regression analyses were employed to evaluate whether adult and parental RF accounted for unique or joint variance in caregivers' emotion socialization behaviors after accounting for caregivers' adverse experiences with childhood caregivers. Adult RF also was tested as a moderator of the relation between caregivers' adverse experiences with childhood caregivers and emotion socialization strategies.ResultsAdult and parental RF each demonstrated unique associations with particular emotion socialization strategies. Adult RF also moderated the association between caregivers' exposure to maladaptive parenting in childhood and emotion socialization behaviors.Conclusion and implicationsFindings suggest that both types of RF are important for caregivers' ability to validate children's emotions and that reflecting on caregiving received in childhood can act as a protective mechanism and help promote effective caregiving behaviors.
Predicting combinations of community mean traits using joint modelling
Authors: Poggiato Giovanni , Gaüzere Pierre , Martinez‐Almoyna Camille , Deschamps Gabrielle , Renaud Julien , Violle Cyrille , Münkemüller Tamara , Thuiller Wilfried 
Published: May 2023

AbstractAimUnderstanding how combinations of ecological traits at the community‐level vary with environmental conditions is crucial to anticipate and respond to the biodiversity crisis. While this topic is popular, most attempts to analyse and predict multiple traits in space and time ignore the inherent correlations between these traits. In doing so, the predicted traits in unobserved environments are likely to be flawed (i.e. unrealistic trait combinations). Here, we propose a framework that addresses this methodological question in functional biogeography.InnovationOur framework relies on joint trait distribution models to quantify how combinations of mean trait values at the community level co‐vary as a function of environmental conditions. Making use of joint probabilities and the constraints imposed by trait correlations, our framework not only predicts the most suitable combination of traits in a given environment but also the envelope of possible alternatives. This innovation allows visualizing how the correlation structure between traits imposes a strong constraint (or not) on the expected combination of traits in a given environment. The stronger trait correlations, the smaller the envelope of likely alternative states. We provide an R package implementing our framework.Main ConclusionsApplied to plant communities in the French Alps, our framework quantifies the variation of trait combinations at the community‐level along environmental gradients that, otherwise, could not be identified. Strong correlations in community mean leaf traits led to a low diversity of alternative combinations of community means, which can only vary along the acquisition‐conservation spectrum. Instead, height varied partly independently of leaf traits, leading to a higher diversity in the combinations of mean community traits. Our framework allows for a more integrated understanding and prediction of the distribution of traits, thus moving a descriptive functional biogeography to a more predictive science.
Carrie's first academic conference—On the possibilities of feminist storytelling and fiction in management
Authors: Winter M. 
Published: May 2023

AbstractIn this article, I make a case for the methodological value of fiction and feminist storytelling to writing practices in management studies as well as provide an example of how this might be done. The epistemological conditions of fiction stimulate feminist critique distinct from the possibilities of autoethnography; we can write with less fear, in new collaborative and beautiful ways, with an audience in mind. Fiction offers us the opportunity to conjure collective dreams, to imagine feminist futures—it allows us to tell stories that simultaneously capture and release us. In practicing this, I present a fictionalized narrative inspired by an experience I had as a first year PhD researcher at a business management conference. There is nothing special or unique about the story. It is made up of the mundane, and yet it is overflowing with thematic significance. The story touches upon the aesthetics of academia, a politics of care, gaslighting, heteronormative assumptions, sexualization, embodiment, and neoliberal feminism, demonstrating how a single interaction can be about very many other, contradicting and co‐productive, things. I offer it as a message of solidarity to those who, like me, may struggle to articulate what exactly just happened, but know in their bodies that it was not fair—that it did not feel right.
Autoantigen‐selected B cells are bystanders in spontaneous T cell‐driven experimental autoimmune hepatitis
Authors: Lübbering David , Preti Max , Schlott Lena , Schultheiß Christoph , Weidemann Sören , Lohse Ansgar W. , Binder Mascha , Carambia Antonella , Herkel Johannes 
Published: May 2023

AbstractAutoreactive B cells are considered pathogenic drivers in many autoimmune diseases; however, it is not clear whether autoimmune B cells are invariably pathogenic or whether they can also arise as bystanders of T cell‐driven autoimmune pathology. Here, we studied the B cell response in an autoantigen‐ and CD4+ T cell‐driven model of autoimmune hepatitis (AIH), the Alb‐iGP_Smarta mouse in which expression of a viral model antigen (GP) in hepatocytes and its recognition by GP‐specific CD4+ T cells causes spontaneous AIH‐like disease. T cell‐driven AIH in Alb‐iGP_Smarta mice was marked by autoantibodies and hepatic infiltration of plasma cells and B cells, particularly of isotype‐switched memory B cells, indicating antigen‐driven selection and activation. Immunosequencing of B cell receptor repertoires confirmed B cell expansion selectively in the liver, which was most likely driven by the hepatic GP model antigen, as indicated by branched networks of connected sequences and elevated levels of IgG antibodies to GP. However, intrahepatic B cells did not produce increased levels of cytokines and their depletion with anti‐CD20 antibody did not alter the CD4+ T cell response in Alb‐iGP_Smarta mice. Moreover, B cell depletion did not prevent spontaneous liver inflammation and AIH‐like disease in Alb‐iGP_Smarta mice. In conclusion, selection and isotype‐switch of liver‐infiltrating B cells was dependent on the presence of CD4+ T cells recognizing liver antigen. However, recognition of hepatic antigen by CD4+ T cells and CD4+ T cell‐mediated hepatitis was not dependent on B cells. Thus, autoreactive B cells can be bystanders and need not be drivers of liver inflammation in AIH.
Effect of possible risk factors for pharyngocutaneous fistula after total laryngectomy of laryngeal carcinomas and surgical wound infection: A meta‐analysis
Authors: Chang Xiaojing , Hu Yuan 
Published: May 2023

AbstractA meta‐analysis study to assess the effect of possible risk factors for pharyngocutaneous fistula (PCF) after total laryngectomy of laryngeal carcinoma. A comprehensive literature examination till January 2023 was implemented and 1794 linked studies were appraised. The picked studies contained 3140 subjects with total laryngectomy of laryngeal carcinomas in the picked studies' baseline, 760 of them were PCF, and 2380 were no PCF. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of possible risk factors for PCF after total laryngectomy of laryngeal carcinomas and surgical wound infection after total laryngectomy of laryngeal carcinoma by the dichotomous and continuous styles and a fixed or random model. The PCF had a significantly higher surgical wound infection (OR, 6.34; 95% CI, 1.89–21.27, P = .003) compared with the no PCF in total laryngectomy of laryngeal carcinomas. The smoking (OR, 1.73; 95% CI, 1.15–2.61, P = .008), and preoperative radiation (OR, 1.90; 95% CI, 1.37–2.65, P < .001) had significantly higher PCF as a risk factor in total laryngectomy of laryngeal carcinomas. The preoperative radiation had a significantly lower spontaneous PCF closure (OR, 0.33; 95% CI, 0.14–0.79, P = .01) compared with the no preoperative radiation in total laryngectomy of laryngeal carcinomas. However, the neck dissection (OR, 1.34; 95% CI, 0.75–2.38, P = .32), and alcohol intake (OR, 1.95; 95% CI, 0.76–5.05, P = .17), had no significant effect on PCF in total laryngectomy of the PCF had a significantly higher surgical wound infection, and preoperative radiation had a significantly lower spontaneous PCF closure in total laryngectomy of laryngeal carcinomas. Smoking and preoperative radiation were shown to be risk factors for PCF, however, neck dissection and alcohol intake were not shown to be risk factors for PCF in total laryngectomy of laryngeal carcinomas. Although precautions should be taken when commerce with the consequences because some of the picked studies for this meta‐analysis was with low sample sizes.
Shared soundscapes: The (re)activation of an institutional and individual archive of Peruvian music and dance
Authors: Barreto Rocío , Cánepa Gisela , Kummels Ingrid , Maradiegue Walther 
Published: May 2023

Abstract“Shared soundscapes” is a key concept that allows us to identify the multiplicity of agencies involved in historical sound recordings and their reactivation today. We use the notion to compare two very different Peruvian case studies concerning Asháninka and Nomatsiguenga peoples of the Central Rainforest and Muchik, Quechua, and mestizo peoples in the Lambayeque region, along with their respective music traditions. Part of their sonic legacy is stored in archives; one was created by an individual anthropologist, and the other is an institutional ethnomusicological archive. The comparison of historical and current soundscapes brings to the fore anthropological issues regarding how a web of actors—among them sonic activists from academia and these communities—have shaped these archives as a process and practice. It raises questions about collaborative approaches to decolonize repositories, which implies handing over rights to individuals and communities so that they can make decisions about their sonic legacies.
The T2‐FLAIR mismatch sign as an imaging biomarker for oligodendrogliomas in dogs
Authors: Garcia‐Mora Josefa , Parker Rell L. , Cecere Thomas , Robertson John L. , Rossmeisl John H. 
Published: May 2023

AbstractBackgroundIn humans, the T2‐weighted (T2W)—fluid‐attenuated inversion recovery (FLAIR) mismatch sign (T2FMM) is a specific imaging biomarker for the isocitrate dehydrogenase 1 (IDH1)‐mutated, 1p/19q non‐codeleted low‐grade astrocytomas (LGA). The T2FMM is characterized by a homogeneous hyperintense T2W signal and a hypointense signal with a hyperintense peripheral rim on FLAIR sequences. In gliomas in dogs, the T2FMM has not been described.Hypotheses/ObjectivesIn dogs with focal intra‐axial brain lesions, T2FMM will discriminate gliomas from other lesions. The T2FMM will be associated with the LGA phenotype and presence of microcysts on histopathology. Interobserver agreement for T2FMM magnetic resonance imaging (MRI) features will be high.AnimalsOne hundred eighty‐six dogs with histopathologically diagnosed focal intra‐axial lesions on brain MRI including oligodendrogliomas (n = 90), astrocytomas (n = 47), undefined gliomas (n = 9), cerebrovascular accidents (n = 33), and inflammatory lesions (n = 7).MethodsTwo blinded raters evaluated the 186 MRI studies and identified cases with the T2FMM. Histopathologic and immunohistochemical slides of T2FMM cases were evaluated for morphologic features and IDH1‐mutations and compared to cases without the T2FMM. Gene expression analyses were performed on a subset of oligodendrogliomas (n = 10) with and without T2FMM.ResultsThe T2FMM was identified in 14/186 (8%) of MRI studies, and all dogs with T2FMM had oligodendrogliomas (n = 12 low‐grade [LGO], n = 2 high‐grade [HGO]; P < .001). Microcystic change was significantly associated with the T2FMM (P < .00001). In oligodendrogliomas with T2FMM, IDH1‐mutations or specific differentially expressed genes were not identified.Conclusion and Clinical ImportanceThe T2FMM can be readily identified on routinely obtained MRI sequences. It is a specific biomarker for oligodendroglioma in dogs, and was significantly associated with non‐enhancing LGO.
Acute cysticercosis caused by Cysticercus tenuicollis in lambs
Authors: Abdollahi Mostafa , Lotfollahzadeh Samad , Shokrpoor Sara , Ashrafi Tamai Iradj 
Published: May 2023

AbstractTwelve 30‐ to 75‐day‐old mixed breed lambs were examined in an intensive system because of sudden recumbency and death. Clinical examination revealed sudden recumbency, visceral pain, and auscultation of respiratory crackles. Lambs died shortly (between 30 minutes and 3 hours) after the onset of clinical signs. The lambs were necropsied, and after routine parasitology, bacteriology and histopathology procedures, the occurrence of acute cysticercosis caused by Cysticercus tenuicollis was confirmed. The use of the suspect infested feed (newly purchased starter concentrate) was discontinued and other lambs of the flock were treated with praziquantel (15 mg/kg, single dose, orally). After these actions, no new cases were observed. The present study showed the importance of preventive measures against cysticercosis in intensive sheep farming systems which include proper storage of feed, preventing feed and environmental access by potential definitive hosts, and implementing consistent parasite control programs in dogs that are in contact with sheep.
Reading the museum
Authors: Chappell Lindsey N. 
Published: May 2023

AbstractThe museum is not a neutral container, a passive collection of art and artifacts. Rather the museum is itself a historical argument, using objects and their relations to write our collective stories. This essay shows how the museum, as it developed within nineteenth‐century European imperialism, directs meaning both within and beyond literature. The museum integrates readers into its collections and its narratives, directing them figuratively and literally through exhibits. Nineteenth‐century literature, I argue, capitalizes on this dynamic interplay among the collection, the viewing subject, and the museum's ideologies. In both poetry and prose the museum appears as a place, a concept, and a form. For example, William Thackeray's “May Day Ode” shows how the Crystal Palace and the 1851 Great Exhibition facilitate an imperialist agenda. The galleries in Jane Austen's Pride and Prejudice and Charlotte Brontë’s Villette, meanwhile, are not just places the characters go; they also exert control over how characters (and readers) experience and evaluate collections. Across these texts, the museum is setting and theme. But, I argue, the museum also works as form, curating the collections, the characters who visit them, and the readers who access the narrative through museum logics. In conjunction with literary examples and an overview of scholarly conversations around nineteenth‐century museum studies, I consider how the museum continues to direct bodies, interpretations, and ideas today by drawing on my experiences using museums in the college classroom.