bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of non-medicinal delousing strategies for parasite (Lepeophtheirus salmonis) removal efficacy and welfare impact on Atlantic salmon (Salmo salar) hosts
Authors: Thompson Cameron R. S. , Madaro Angelico , Nilsson Jonatan , Stien Lars Helge , Oppedal Frode , Øverli Øyvind , Korzan Wayne J. , Bui Samantha 
Published: June 2023

AbstractSince salmon lice have developed resistance to pesticides, non-medicinal delousing treatments have become increasingly used to remove the parasite from fish on salmon farms in Norwegian waters. These novel techniques are an important means of controlling epidemics of lice at farms for maintaining the health of farmed fish and for preventing the spread of lice to wild salmonid populations. However, some treatments are associated with higher mortality rates and negative welfare impacts on the host fish. Furthermore, it is unclear how effective each treatment is in removing lice compared to alternatives. Here, in a controlled laboratory environment, we tested the efficacy of mechanical, warm water (28 °C and 34 °C), and freshwater treatments alone and in combination, and examined their welfare impact on host fish. Regardless of treatment group or control, the handling of fish through the experiment led to a reduction in lice load and decline in fish welfare. Among the treatments examined, the freshwater bath alone and in combination with other treatments had the greatest delousing efficacy. The 34 °C warm water baths also significantly reduced lice loads but led to worse welfare outcomes with fish having a higher prevalence of injuries and reduced growth and condition factor. Delousing treatments were however not associated with long-term effects on neuroendocrine parameters or stress coping ability, suggesting that immediate welfare impacts from these procedures are generally reversible. It was also found that sedating fish prior to treatment was shown to mitigate the welfare impact. These findings are useful for the needed optimization of delousing strategies for greater delousing efficacy and reduced welfare impact on fish.
Shaking table test and numerical analyses of a full scale three-leaf masonry wall
Authors: Di Michele Francesco , Spacone Enrico , Camata Guido , Brando Giuseppe , Sextos Anastasios , Crewe Adam , Mylonakis George , Diez Matt , Dihoru Luiza , Varum Humberto 
Published: June 2023

AbstractThis paper discusses the main results of a full-scale shaking table test campaign carried out under the auspices of the EU funded research project SERA, whose objective is to investigate the seismic performance of three-leaf masonry walls with weak lime-mortar joints. These masonry walls are widely found in seismic prone regions in the Mediterranean area, thus assessing their behaviour under dynamic actions is an important pre-requisite for the seismic vulnerability evaluation of a plethora of historical centres. The first part of the paper presents a preliminary study on the mechanical properties of the wall component materials that was carried out through an ad-hoc experimental campaign. The outcomes are of particular interest for the characterization of the mortar and of the infill materials, that were designed to reproduce the low strength that is typically found in old masonry buildings. The design of the masonry wall that was tested and the test set-up are presented next. The applied loading protocol consisted of the horizontal component of a ground motion record that is repeatedly applied to the shaking table with increasing intensity. Finally, the main results of the experimental test are discussed. The damage patterns, drift ratios and base shear are presented for the ground motion sequence. The results are also discussed through a dynamic capacity curve that shows the attainment of different limit states with increasing ground motion intensity. A set of nonlinear numerical simulations, both static and dynamic, using a 3D FE model of the wall verify the experimental study as they report good agreement with the experimental tests and exhibit stable numerical behaviour.
Room temperature manufacture of dense NaSICON solid electrolyte films for all-solid-state-sodium batteries
Authors: Sozak Mutlucan , Nazarenus Tobias , Exner Jörg , Kita Jaroslaw , Moos Ralf 
Published: June 2023

AbstractSodium (Na) Super-Ionic CONductor (NaSICON) solid electrolyte (SE) powders (Na3Zr2Si2PO4) were prepared by the mixed oxide technique using a planetary ball mill and synthesized via solid-state method at temperatures ranging from 950 to 1200 °C. The powders with 95% pure NaSICON phase were deposited on different substrates via Powder Aerosol Deposition (PAD) at room temperature directly from the powders and fully dense ceramic films were obtained. X-ray diffractometry including Rietveld refinement were carried out on both the calcined powders and the resulting films to determine the crystallographic properties. Subsequently, the electrical properties of the resulting films were characterized and the effect of annealing at temperatures between 100 and 600 °C on the ionic conductivity of NaSICON PAD films was evaluated. Annealed films were measured in the temperature range 50 and 250 °C to calculate the activation energy Ea of the PAD films. Our work demonstrates a successful room temperature deposition of dense NaSICON electrolyte films on different substrates, which is promising for stationary energy storage applications of solid-state-sodium batteries.
Bifurcations and Early-Warning Signs for SPDEs with Spatial Heterogeneity
Authors: Bernuzzi P. , Kuehn C. 
Published: June 2023

Abstract
Bistability is a key property of many systems arising in the nonlinear sciences. For example, it appears in many partial differential equations (PDEs). For scalar bistable reaction-diffusions PDEs, the bistable case even has taken on different names within communities such as Allee, Allen-Cahn, Chafee-Infante, Nagumo, Ginzburg-Landau,

$$\Phi ^4$$

Φ
4

, Schlögl, Stommel, just to name a few structurally similar bistable model names. One key mechanism, how bistability arises under parameter variation is a pitchfork bifurcation. In particular, taking the pitchfork bifurcation normal form for reaction-diffusion PDEs is yet another variant within the family of PDEs mentioned above. More generally, the study of this PDE class considering steady states and stability, related to bifurcations due to a parameter is well-understood for the deterministic case. For the stochastic PDE (SPDE) case, the situation is less well-understood and has been studied recently. In this paper we generalize and unify several recent results for SPDE bifurcations. Our generalisation is motivated directly by applications as we introduce in the equation a spatially heterogeneous term and relax the assumptions on the covariance operator that defines the noise. For this spatially heterogeneous SPDE, we prove a finite-time Lyapunov exponent bifurcation result. Furthermore, we extend the theory of early warning signs in our context and we explain, the role of universal exponents between covariance operator warning signs and the lack of finite-time Lyapunov uniformity. Our results are accompanied and cross-validated by numerical simulations.
Does Forgiveness Underlie the Relationship Between Religiosity and Meaning in Life Among Members of Sexaholics Anonymous in Poland?
Authors: Wnuk Marcin , Charzyńska Edyta 
Published: June 2023

AbstractReligiosity and meaning in life are recognized as factors supporting recovery from addictions. However, little is known about the moral mechanisms involved in the relationship between religiosity and meaning in life among individuals with addictions. The main purpose of this study was to test the direct and indirect (through forgiveness by God/higher power and interpersonal forgiveness) relationships between subjective religiosity and the presence of meaning in life among 80 members (72 men and 8 women) of Sexaholics Anonymous (SA) in Poland. The following measures were used: a single-item measure of subjective religiosity, subscales from the Forgiveness Scale and the Heartland Forgiveness Scale, and the Meaning in Life Questionnaire. The sequential mediation model was tested using Hayes PROCESS macro. The results showed a direct positive relationship between subjective religiosity and the presence of meaning in life. Moreover, subjective religiosity was positively related to forgiveness by God/higher power, which, in turn, directly and indirectly (through interpersonal forgiveness) predicted higher levels of the presence of meaning in life. The study suggests that among SA members, religious faith facilitates perceiving one’s own life as meaningful, both directly and indirectly, through aspects of forgiveness. Members of SA may benefit from their belief in God/higher power and religiously-rooted forgiveness to support the meaning-making processes.
Unified Approach of Interior-Point Algorithms for $$P_*(\kappa )$$-LCPs Using a New Class of Algebraically Equivalent Transformations
Authors: Illés Tibor , Rigó Petra Renáta , Török Roland 
Published: June 2023

AbstractWe propose new short-step interior-point algorithms (IPAs) for solving $$P_*(\kappa )$$

P

∗

(
κ
)

-linear complementarity problems (LCPs). In order to define the search directions, we use the algebraic equivalent transformation (AET) technique of the system describing the central path. A novelty of the paper is that we introduce a whole, new class of AET functions for which a unified complexity analysis of the IPAs is presented. This class of functions differs from the ones used in the literature for determining search directions, like the class of concave functions determined by Haddou, Migot and Omer, self-regular functions, eligible kernel and self-concordant functions. We prove that the IPAs using any member $$\varphi $$
φ
of the new class of AET functions have polynomial iteration complexity in the size of the problem, in starting point’s duality gap, in the accuracy parameter and in the parameter $$\kappa $$
κ
.
A review on the thermal conductivity of deep eutectic solvents
Authors: Atilhan Mert , Aparicio Santiago 
Published: June 2023

AbstractDeep eutectic solvents may develop a pivotal role in future technologies considering sustainability and safety as pivotal aspects for chemistry developments. The possible application of these fluids for heat transfer operations is of great relevance for which the knowledge of thermal properties such as thermal conductivity is required as well as inferring structure–property relationships which allow reverse design of the fluids according to the technological requirements. Considering the technological relevance of this property, the available literature on the thermal conductivity for deep eutectic solvents is critically discussed showing strengths and weaknesses. The analysis of the state-of-the-art shows the future needs in this research field considering the application of these solvents for thermal-related technologies. The review indicates the scarcity of reliable experimental data and the need of predictive methods, which could be used for process design and solvent screening purposes. Likewise, considering the relevance of developing predictive methods for in silico design of these fluids according to industrial needs, the available predictive theoretical approaches are analysed showing their reliability as well as future needs. Finally, considering the need of developing suitable and reliable structure–property relationship, the molecular level basis of thermal conductivity in deep eutectic solvents is discussed, showing the role of hydrogen bonding and the effects rising from the involved hydrogen bond donors and acceptors as well as the eutectic compositions. This work reports the first literature review and analysis on thermal conductivity for deep eutectic solvents considering an experimental and theoretical approach as well as providing support for the molecular basis of this technologically relevant property, thus contributing to the development of environmentally friendly materials for thermal-related technologies.
Graphical abstract
Non-classical correlations of accelerated observers interacting with a classical stochastic noise beyond the single mode approximation
Authors: Abd-Rabbou M. Y. , Shamirzaie M. , Khan Salman 
Published: June 2023

AbstractThis paper investigates the behaviour of the quantum correlations for an accelerated two-qubit system during its interaction with a classical stochastic field, utilizing the Wigner function and concurrence. The non-classical behaviour is indicated by negative values of the Wigner function, while the degree of entanglement is demonstrated by the concurrence. To consider acceleration and interaction with a common or independent environment, we discard the single-mode approximation and utilize the Unruh construction of the quantum field mode in our analysis. Our results suggest that coherence suppression is caused by the acceleration effect, noise strength, and noise frequency. Through an examination of quantum concurrence, this study analyses the level of quantum entanglement that corresponds positively with negative values of the Wigner function. The findings indicate that coherence degradation in the initial system is reduced when observers interact independently with their environments, as opposed to interacting with a common environment. Additionally, the acceleration of both observers has an impact on coherence reduction. During system evolution, the Wigner function displays collapse and reappearance behaviour, while quantum entanglement undergoes local collapse and revival phenomena. Notably, common noise situations exhibit more rapid variation in both the Wigner function and entanglement compared to independent noise configurations.
Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment
Authors: Fang Yimin , Medina David , Stockwell Robert , McFadden Sam , Quinn Kathleen , Peck Mackenzie R. , Bartke Andrzej , Hascup Kevin N. , Hascup Erin R. 
Published: June 2023

Abstract
Senolytic treatment in aged mice clears senescent cell burden leading to functional improvements. However, less is known regarding the effects of these compounds when administered prior to significant senescent cell accumulation. From 4–13 months of age, C57BL/6 male and female mice received monthly oral dosing of either 100 mg/kg Fisetin or a 5 mg/kg Dasatinib (D) plus 50 mg/kg Quercetin (Q) cocktail. During treatment, several aspects of healthy aging were assayed including glucose metabolism using an insulin and glucose tolerance test, cognitive performance using Morris water maze and novel object recognition, and energy metabolism using indirect calorimetry. Afterwards, mice were euthanized for plasma, tissue specific markers of senescence-associated secretory phenotype (SASP), and white adipose tissue accumulation (WAT). Sexually dimorphic treatment effects were observed. Fisetin treated male mice had reduced SASP, enhanced glucose and energy metabolism, improved cognitive performance, and increased mRNA expression of adiponectin receptor 1 and glucose transporter 4. D + Q treatment had minimal effects in male C57BL/6 mice, but was detrimental to females causing increased SASP expression along with accumulation of WAT depots. Reduced energy metabolism and cognitive performance were also noted. Fisetin treatment had no effect in female C57BL/6 mice potentially due to a slower rate of biological aging. In summary, the senolytic treatment in young adulthood, has beneficial, negligible, or detrimental effects in C57BL/6 mice dependent upon sex and treatment. These observations should serve as a note of caution in this rapidly evolving and expanding field of investigation.
Graphical Abstract
Male and female C57BL/6 mice were treated with once monthly oral doses of either Dasatinib (D) + Quercetin (Q) or Fisetin from 4–13 months of age. Males treated with Fisetin had reduced SASP markers (blue spheres) as well as improved metabolism (red flame) and cognition. Females treated with D + Q had increased adiposity and SASP markers (red spheres) along with decreased metabolism (blue flame) and cognitive performance. No effects were observed in females treated with Fisetin or males treated with D + Q.
Internalisation of environmental costs of decentralised nitrogen fertilisers production
Authors: Osorio-Tejada Jose Luis , Rebrov Evgeny , Hessel Volker 
Published: June 2023

Abstract
Purpose
Ammonia (NH3) production is an energy-intensive process that is concentrated in a few countries at large-scale plants, mainly using the Haber–Bosch (HB) process. Local plants next to farmers can reduce environmental impacts, as well as reduce storage, shortage risks, and price volatility of fertilisers. Since local NH3 production is not cost-effective, we analyse how internalisation of environmental impacts into economic analyses could help to promote novel technologies for NH3 synthesis when supplied with renewable energy.

Methods
Mini-HB plants working at high pressure and temperature, as well as novel alternatives based on plasma reactors working at ambient conditions and using electricity from renewable sources, have been recently proposed for decentralised NH3 production. To evaluate the environmental performances of these alternative and traditional NH3 pathways, a life cycle assessment was performed to quantify the reduced emissions in each production process and the impacts of by-product utilisation, such as steam, oxygen, or carbon black. Different scales of storage and transportation, fuelled by traditional energy sources, were modelled to quantify the impacts of the simplified NH3 supply chains. A review of monetary valuation coefficients was performed to internalise the life cycle environmental impacts into the techno-economic analyses of NH3 production in Australia.

Results and discussion
Most of the estimated environmental costs were due to the carbon emissions of conventional plants and thermal plasma plants because of the use of fossil-based electricity. However, the high external costs associated with the photochemical oxidant formation and particulate matter affected the thermal plasma and non-thermal plasma (NTP) plants, costing in total 9,500 and 4,200 $/t NH3, respectively, due to the impacts of solar panels manufacturing. In contrast, electrolyser-HB plants obtained rates of 114 $/t NH3 because of the high energy efficiency and oxygen sales. In the future scenario for NTP-based plants, this alternative could also be competitive with rates of 222 $/t NH3. Additionally, the estimated total external costs for the conventional NH3 industry in Australia amounted to about US$5 billion per year.

Conclusions
Electrolyser-HB plants could be cost-effective in the short term due to the energy efficiency of HB processes. However, the HB process has reached its efficiency limits, while the NTP process still has room for improvement, as well as its production costs are lower at smaller scales. In addition, if monetised environmental costs are analysed for a whole industry, public administrations could be prompted to invest the expected savings in the promotion of these novel technologies.
Problematic Internet Use, Online Racism, and Mental Health Issues Among Racially Minoritized Emerging Adults in the United States
Authors: Keum Brian TaeHyuk , Valdovinos Irene C. , Wong Michele J. 
Published: June 2023

AbstractProblematic internet use has been linked with numerous mental health issues. However, little research has examined the relevant factors that may explain this association. For racially minoritized individuals, problematic internet use may increase the likelihood of encountering race-based cyberaggression and racist content, commonly known as online racism. Thus, we examined whether problematic internet use is associated with mental health issues through exposure to online racism. Using data from 338 racially minoritized emerging adults (Mage = 23.28, SD = 2.38), we conducted a path analysis of problematic internet use predicting mental health issues (anxiety, depressive symptoms, loneliness) via online racism. The indirect relationship was significant suggesting that problematic internet use is associated with greater perceived online racism, which in turn was associated with greater depressive symptoms, anxiety, and loneliness. Online racism is likely a digital inequity that disproportionately impacts the costs of problematic internet use among racially minoritized emerging adults.
Bone marrow-derived mesenchymal stem cells transplantation downregulates pancreatic NF-κB and pro-inflammatory cytokine profile in rats with type I and type II-induced diabetes: a comparison study
Authors: Farid Alyaa , El-Alfy Lamiaa , Madbouly Neveen 
Published: June 2023

AbstractDiabetes mellitus (DM) is a set of metabolic diseases defined by a persistently high blood sugar level. Mesenchymal stem cells (MSCs) are a novel potential therapeutic intervention in treatments of various diseases, which is also referred to as regenerative medicine. We aimed to compare the pro-inflammatory cytokines’ levels during bone marrow mesenchymal stem cells (BM-MSCs) transplantation in rats with induced type I (T1D) and type II diabetes (T2D). Thirty-five male Sprague dawley rats were divided into: Group I: the healthy control group, group II: untreated rats with streptozotocin (STZ)-induced T1D (65 mg/kg), group III: BM-MSCs treated rats with STZ-induced T1D, group IV: untreated rats with high-fat diet (HFD)/STZ-induced T2D (40 mg/kg), group V: BM-MSCs-treated rats with HFD/STZ-induced T2D. Biochemical, histopathological and immunohistochemical studies were applied. Our results showed that transplantation reduced hyperglycemia and increased insulin levels in both induced T1D and T2D. Also, reductions in the levels of inflammatory markers were noticed after transplantation that was coincided with nuclear factor-kappa B (NF-кB) immunohistochemical results; which showed negative or moderate cytoplasmic reactivity in treated groups III and V. These results indicated the ability of BM-MSCs transplantation to modulate the pro-inflammatory cytokine profile during treatment of both T1D and T2D.