bluuebunny/crossref_metadata_2025_split huggingface dataset:
AtMYB50 regulates root cell elongation by upregulatingPECTIN METHYLESTERASE INHIBITOR 8inArabidopsis thaliana
Authors: Mase Kosuke , Mizuno Honomi , Nakamichi Norihito , Suzuki Takamasa , Kojima Takaaki , Kamiya Sho , Takeuchi Taiga , Kondo Chiko , Yamashita Harumi , Sakaoka Satomi , Morikami Atsushi , Tsukagoshi Hironaka 
Published: April 2023

AbstractPlant root development is regulated by several signal transduction pathways. Among them, plant phytohormones, like auxin and cytokinin, are well characterized for their molecular mechanisms of action. Reactive oxygen species (ROS) play important roles as signaling molecules in controlling root development. Under these signal transduction pathways, the gene regulatory network, which is controlled by transcription factors, is the key to regulating root growth. We have previously reported an important transcription factor,UP BEAT1(UPB1), that regulates ROS homeostasis at the root tip, further controlling the transition from cell proliferation to differentiation. Although UPB1 directly regulates the expression of several peroxidases that control ROS homeostasis, UPB1 still targets genes other than peroxidases. This indicates that UPB1 may regulate root growth through different ROS signals. Here, we investigated the function of the transcription factorMYB50, a direct target of UPB1, inArabidopsis thaliana. We then examined whether UPB1 regulatesMYB50expression in the roots using an induction expression system and imaging of multiple fluorescent proteins. We also performed RNA-Seq analysis usingMYB50estradiol induction lines and ChIP-seq analysis to identify theMYB50regulatory gene network. Integrating these analyses withUPB1regulatory network revealed that MYB50 regulates the expression ofPECTIN METHYLESTERASE INHIBITOR 8(PMEI8). These data suggest thatMYB50is a new root growth regulator under theUPB1gene regulatory network, which differs from the control of ROS homeostasis. Our study presents a model including a new transcriptional network under MYB50 into UPB1 regulatory root growth system and will provide novel insights into the cell elongation controlled by pectin modification.
Big data analytics and auditor judgment: an experimental study
Authors: Sihombing Ranto Partomuan , Narsa I Made , Harymawan Iman 
Published: April 2023

Purpose
Auditors’ skills and knowledge of data analytics and big data can influence their judgment at the audit planning stage. At this stage, the auditor will determine the level of audit risk and estimate how long the audit will take. This study aims to test whether big data and data analytics affect auditors’ judgment by adopting the cognitive fit theory.

Design/methodology/approach
This was an experimental study involving 109 accounting students as participants. The 2 × 2 factorial design between subjects in a laboratory setting was applied to test the hypothesis.

Findings
First, this study supports the proposed hypothesis that participants who are provided with visual analytics information will rate audit risk lower than text analytics. Second, participants who receive information on unstructured data types will assess audit risk (audit hours) higher (longer) than those receiving structured data types. In addition, those who receive information from visual analytics results have a higher level of reliance than those receiving text analytics.

Practical implications
This research has implications for external and internal auditors to improve their skills and knowledge of data analytics and big data to make better judgments, especially when the auditor is planning the audit.

Originality/value
Previous studies have examined the effect of data analytics (predictive vs anomaly) and big data (financial vs non-financial) on auditor judgment, whereas this study examined data analytics (visual vs text analytics) and big data (structured and unstructured), which were not tested in previous studies.
Facilitating professional learning for technology coaches through cross-district collaboration
Authors: Gallagher Tiffany L. , Grierson Arlene , Susin Catherine A. 
Published: April 2023

Purpose This two-year study illuminates the experiences of technology coaches (digital learning coaches [DL] and science technology engineering and mathematics/literacy coaches [STEM/L]) as they engaged in their own professional learning (PL) facilitated by a faculty researcher.Design/methodology/approach Technology coaches from different school districts and their respective colleagues participated in book studies as part of their PL. They reflected and debriefed individually and collaboratively with a researcher facilitator. Data were collected through interviews, field notes at meetings, observations, researchers’ reflections and artefacts. Qualitative data analysis methods were employed.Findings The findings offer a glimpse into (1) benefits of cross-district collaboration, (2) challenges finding resources for coaching, (3) career-long desire to learn and (4) time to build and sustain cross-collaborations.Practical implications Conclusions suggest that DL and STEM/L coaches benefit from their own dedicated, differentiated programme of PL supported by each other (as from other districts) and a researcher facilitator. Educational implications are offered for researchers and other school district stakeholders for consideration for them to foster coaches’ collaborative PL.Originality/value Importantly, this project is an exemplar of how to support coaches’ PL and growth through researcher facilitation of cross-district collaborative learning.
IFRS and the evolution of value relevance: evidence from an African developing country
Authors: Gowry Yuveshna , Subadar Agathee Ushad , Soobaroyen Teerooven 
Published: April 2023

Purpose
This study aims to assess the evolution of the value relevance of book value, earnings and its components in Mauritius, an African developing country, focusing on value relevance changes after International Financial Reporting Standards (IFRS) adoption and subsequent local reforms.

Design/methodology/approach
The study relies on a data set of 567 firm-year observations (2001–2018) and the Ohlson valuation model to investigate value relevance after IFRS adoption, the implementation of institutional reforms and enforcement reforms.

Findings
Firstly, the authors find support for a rise in the combined value relevance of earnings and book value, albeit that book value significantly contributes to changes over time. The findings highlight the combined importance of IFRS adoption with institutional and enforcement reforms to improve value relevance. Secondly, the authors do not find evidence of a shift in value relevance between earnings and book value. Third, the cash flow model reveals a higher level of significance relative to the earnings model.

Originality/value
The authors extend the value relevance literature in the context of African developing countries. The present findings underpin the need for a reinforcing of relevant institutional and enforcement frameworks to ensure the benefits of IFRS adoption materialise. The findings also offer a contribution of how developing countries’ experience IFRS post-adoption while adding to the dearth of studies analysing IFRS enforcement practices.
Dynamic capabilities in new product development – the role of operational capabilities
Authors: Kunanoppadol Jarut , Igel Barbara 
Published: April 2023

PurposeThis research investigated the individual and combined effects of dynamic and operational capabilities on new product success using an improved measurement instrument.Design/methodology/approachThe empirical data were collected from 872 manufacturing firms in Thailand via a questionnaire survey. Then data were analyzed by covariance-based structural equation modeling.FindingsThe improved measurement instrument provided good reliability and validity. Dynamic capabilities improved new product success through operational capabilities, which fully mediated this relationship. Dynamic capabilities negatively moderated the effect of operational capabilities on new product success.Research limitations/implicationsThe empirical model derived from private manufacturing company data should be further tested in service industries, public firms and nonprofit organizations.Practical implicationsThe research provided two implications: the complementarity between dynamic capabilities and operational capabilities and the measurement instruments and the industrial benchmarks.Originality/valueThis study contributes three new insights: firstly, the complementary role of dynamic capabilities and operational capabilities supporting new product success; secondly, the mediating role of operational capabilities and thirdly, the moderating role of dynamic capabilities in this relationship.
Retrieval‐based learning in special education
Authors: Tempel Tobias , Sollich Sebastian 
Published: April 2023

AbstractRetrieval‐based learning has been investigated in various populations. The present study examined retrieval‐based learning in a sample of students at a special‐needs school with educational tracks for learning and mental development. In addition, a comparison group of students at a regular school was examined. Learning conditions were manipulated within participants. In a first session, participants either received restudy cycles only, or they received alternating test and restudy cycles. A second session then comprised the opposite form of practice. In both sessions, a final test assessed memory after a short distractor phase. This procedure was the same in two experiments but with different kinds of item material. For both kinds (images and image‐word pairs), a testing effect occurred, that is higher recall of tested items. These results show that lower cognitive ability or lack of experience with regularly being tested in school do not prevent students from benefiting from retrieval‐based learning.
Evaluating digital video transcoding for forensic derivative results
Authors: Bruehs Walter E. , Stout Dorothy 
Published: April 2023

AbstractVideo data received for analysis often come in a variety of file formats and compression schemes. These data are often transcoded to a consistent file format for forensic examination and/or ingesting into a video analytic system. The file format often requested is an MP4 file format. The MP4 file format is a very common and a universally accepted file format. The practical application of this transcoding process, across the analytical community, has generated differences in video quality. This study sought to explore possible origins of the differences and assist the practitioner by defining minimum recommendations to ensure that quality of the video data is maintained through the transcoding process. This study sought to generate real world data by asking participants to transcode provided video files to an MP4 file format using programs they would typically utilize to perform this task. The transcoded results were evaluated based on measurable metrics of quality. As the results were analyzed, determining why these differences might have occurred became less about a particular software application and more about the settings employed by the practitioner or of the capabilities of the program. This study supports the need for any video examiner who is transcoding video data to be cognizant of the settings utilized by the programs employed for transcoding video data, as loss of video quality can affect analytics as well as further analysis.
Effect of chemical pretreatment on quality attributes of the cashew apple
Authors: Ghag Saurabhi S. , Gokhale Jyoti S. , Lele S. S. 
Published: April 2023

AbstractCashew apples, tropical pseudo fruit, are rich in bioactive compounds. It is still underutilized due to its high perishability and its astringent flavor. This study aims to extend its shelf life by chemical dip and dry method at the rural level. Inhibition of fruit‐spoiling enzymes, such as polyphenol oxidase (PPO), peroxidase (POD), amylase, and cellulase, was a significant response in this method. Enzyme inhibition was carried out using chemicals: NaCl (1–10 mM), CaCl2 (1–10 mM), and ethylenediamine tetraacetic acid (0.1–1 mM). The effect of chemical concentration and dipping time was studied using a full factorial method at three levels (−1, 0, and 1). The dipping time ranged from 60 to 180 min, and chemical concentrations from 1 to 10 mM were studied. Optimal treatment conditions were obtained as follows: NaCl concentration of 9.45 mM, dipping time of 160 min, and CaCl2 concentration of 7.8 mM, dipping time of 160 min. NaCl pretreatment showed maximum inhibition of PPO (>80%) and POD (>80%), whereas CaCl2 pretreatment showed maximum inhibition of amylase (60.58%) and cellulase (80.23%). Hence, to avoid postharvest losses, pretreatment with NaCl and CaCl2 was adequate to preserve the texture and color of cashew apples.Practical Application
Chemical pretreatment can prevent the postharvest losses of cashew apples.
Inhibition of PPO, POD, amylase, and cellulase is vital in the shelf‐life extension of cashew apples.
Sodium chloride dip is a cost‐effective method for increasing the storability of cashew apples.
Manipulating spectra of artificial light affects movement patterns of bats along ecological corridors
Authors: Barré K. , Thomas I. , Le Viol I. , Spoelstra K. , Kerbiriou C. 
Published: April 2023

AbstractAnimal movement throughout the landscape is a key concept for population viability. Human footprint can reduce animal movement through barrier effects such as habitat change and fragmentation, or through enhanced resources. Artificial light at night (ALAN) can affect the movement of nocturnal animals such as bats that are highly mobile in the landscape. Very few studies have explicitly quantified the choices that moving bats make when they encounter a light source on their flight routes. We assessed whether ALAN of different colours (green, red and white) compared to control conditions affected the use of ecological corridors, considering (i) activity and (ii) movement along the corridor, for open, edge (i.e. light‐opportunistic) and narrow‐space (i.e. light‐averse) foraging bats. We modelled the effects of 28 independent lampposts at four experimental sites on bat activity and movement (i.e. the number of trajectories towards the lamppost and the probability of lamppost crossing). Each lamppost was sampled two to three times over eight complete nights using paired passive acoustic stereo recorders to record bat activity and reconstruct bat trajectories. Narrow‐space foragers were much less active in presence of any light source, and fewer flew towards any lit lampposts. Open and edge‐space foragers were more active close to white and green lights, and to a lesser extent red light, compared to unlit control sites. Edge‐space foragers overall flew more towards white and green lampposts, but had a lower probability of fully crossing a white and red‐lighted site. The study shows that ALAN can strongly alter bat movements along landscape structures, for light‐averse but also light‐opportunistic species. Such changes in flight behaviour may involve bypasses or detours, which may force bats to fly longer distances at night which could ultimately affect fitness. Our findings suggest that avoiding artificial lighting close to flight routes will benefit bats.
International trade of lead for glazed tile production in ancient East Asia
Authors: Chang Dongxue , Cui Jianfeng , Song Yubin , Zhao Zhefu , Quan Renxue , Zhang Liangren 
Published: April 2023

AbstractGlazed tiles were prestigious building materials reserved for embellishing the roofs of royal architectures of ancient states in East Asia. This paper, by studying glazed tiles from the palace precincts of Shangjingcheng, Xigucheng, and Baliancheng, three capital cities of the Bohai state (698–926 ad), aims to expose the vibrant technological and economic interactions among ancient states of East Asia untold in historical chronicles. Although it is well recorded that Bohai maintained intimate political, cultural, and commercial engagements with the Tang empire and the Yamato state, it is obscure what kinds of technology and commodities were involved in these activities. It appears that the bodies of these tiles were produced of local iron‐rich clays, and the glazes were made of compounds of the same clays and lead materials. The glazing technique may have been transmitted from the Tang empire yet modified in response to local circumstances. Lead materials were acquired from various sources, partly from the one for the Huangye sancai wares in the Tang empire, and partly from the one for Nara sancai wares of the Yamato state in Japan. Archaeology is therefore capable of enriching our knowledge of the human past, even in the historical period.
Safety of topical medications in the management of paediatric atopic dermatitis: An updated systematic review
Authors: Zhao Sharon , Hwang Austin , Miller Corinne , Lio Peter 
Published: April 2023

AimNew topical agents have been developed for the treatment of atopic dermatitis (AD) in recent years. This systematic review is intended to synthesize the clinical trial literature and concisely report the updated safety and adverse effects of topical medications used to treat atopic dermatitis in children.MethodsA systematic search of Cochrane Library, Embase, PubMed and ClinicalTrials.gov from inception to March 2022 was conducted for trials of topical medications used to treat AD in patients <18 years (PROSPERO #CRD42022315355). Included records were limited to English‐language publications and studies of ≥3 weeks duration. Phase 1 studies and those that lacked separate paediatric safety reporting were excluded.ResultsA total of 5005 records were screened; 75 records met inclusion criteria with 15 845 paediatric patients treated with tacrolimus, 12 851 treated with pimecrolimus, 3539 with topical corticosteroid (TCS), 700 with crisaborole and 202 with delgocitinib. Safety data was well reported in tacrolimus trials with the most frequently reported adverse events being burning sensation, pruritus and cutaneous infections. Two longitudinal cohort studies were included, one for tacrolimus and one for pimecrolimus, which found no significant increased risk of malignancy with topical calcineurin inhibitor (TCI) use in children. Skin atrophy was identified as an adverse event in TCS trials, which other medications did not. Systemic adverse events for the medications were largely common childhood ailments.ConclusionData discussed here support the use of steroid‐sparing medications (tacrolimus, pimecrolimus, crisaborole, delgocitinib) as safe options with minimal adverse events for managing paediatric AD, although a larger number of TCI studies reported burning and pruritus compared to TCS studies. TCS was the only medication class associated with reports of skin atrophy in this review. The tolerability of these adverse events should be considered when treating young children. This review was limited to English‐language publications and the variable safety reporting of trial investigators. Many newer medications were not included due to pooled adult and paediatric safety data that did not meet inclusion criteria.
Significant haemoglobinopathies: A guideline for screening and diagnosis
Authors: Bain Barbara J. , Daniel Yvonne , Henthorn Joan , de la Salle Barbara , Hogan Amanda , Roy Noémi B. A. , Mooney Ciaran , Langabeer Lisa , Rees David C. ,   the BSH Committee
Published: April 2023

SummaryAntenatal screening/testing of pregnant women should be carried out according to the guidelines of the National Health Service (NHS) Sickle Cell and Thalassaemia Screening Programme. Newborn screening and, when necessary, follow‐up testing and referral, should be carried out according to the guidelines of the NHS Sickle Cell and Thalassaemia Screening Programme. All babies under 1 year of age arriving in the United Kingdom should be offered screening for sickle cell disease (SCD). Preoperative screening for SCD should be carried out in patients from ethnic groups in which there is a significant prevalence of the condition. Emergency screening with a sickle solubility test must always be followed by definitive analysis. Laboratories performing antenatal screening should utilise methods that are capable of detecting significant variants and are capable of quantitating haemoglobins A2 and F at the cut‐off points required by the national antenatal screening programme. The laboratory must ensure a provisional report is available for antenatal patients within three working days from sample receipt.
Real‐world systemic treatment of patients with psoriasis: A retrospective study based on German claims data
Authors: Heidbrede Tanja , Mevius Antje , Kessel Sebastian , Wilke Thomas , Maywald Ulf , Thiem Alexander 
Published: April 2023

SummaryBackground and objectivesPsoriasis is a common skin disorder with a high physical and psychological burden for patients. Up to 30% of the patients are candidates for a systemic treatment. The aim of this study was to describe the characteristics and the real‐world systemic treatment of psoriasis patients.Patients and methodsThis study was based on German medical claims data. A cross‐sectional analysis observed all psoriasis patients in 2020. A longitudinal analysis was conducted, addressing psoriasis patients who newly started a systemic treatment.ResultsIn total, 116,507 prevalent psoriasis patients and 13,449 newly treated patients were followed. Of all prevalent patients, 15.2% received systemic treatment in 2020 (8.7% systemic corticosteroids). Of the newly treated patients, 95.2% started with conventional treatment (79.2% systemic corticosteroids), 4.0% with biologics and 0.9% with apremilast. The rate of treatment discontinuation/switch after one year was highest for corticosteroids (91.3%) and lowest for biologics (23.1%).ConclusionsAround 15% of psoriasis patients in Germany received a systemic treatment, with > 50% of these prescribed systemic corticosteroids. Therefore, we conclude that systemic treatment is not in line with guideline recommendations in a substantial number of observed patients. The lowest discontinuation/switch rates for biologics support their wider use.
The spatial and economic relationship between labour informality and homicides in Cali, Colombia
Authors: Herrera Giraldo Magaly Faride , González Espitia Carlos Giovanni , Ochoa Díaz Héctor 
Published: April 2023

AbstractMotivationIn the analysis of the relationship between the labour market and crime, the variable that comes from the labour market is generally the unemployment rate. However, there are labour market characteristics that are more significant than unemployment, such as labour informality, in the context of violent crime in low‐income and middle‐income countries.PurposeThis article aims to estimate the spatial and economic relationship between homicides and labour informality by neighbourhood in Cali, the city with the highest homicide rate currently and historically in Colombia.Methods and approachUsing administrative data and a unique survey of formal and informal labour market conditions, we estimate a Spatial Durbin Model to capture the spatial endogeneity of the relationship between homicides and the labour market in the city's neighbourhoods.FindingsThe main results show evidence of the positive spatial and economic relationship between labour informality and homicides in the city's neighbourhoods. In addition, the bulk of this effect occurs in some hillside settlement neighbourhoods with characteristics associated with acute labour informality.Policy implicationsWe propose a social and economic development programme to improve the conditions of the informal labour market and therefore achieve a reduction in homicides in specific areas, such as city hot spots found in our spatial results.