bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of oral Mirtogenol on retinal ganglion cell apoptosis index and intraocular pressure in the Wistar glaucoma model
Authors: Andika Yustiadenta Widya , Jannah Silka Roudhatul , Winarto  , Wildan Arief , Rahmi Fifin Luthfia , Prihatningtyas Riski , Mulyanto Joko , Maharani  
Published: August 2023

ABSTRACT
The purpose of this research is to determine how Mirtogenol affects intraocular pressure (IOP) and retinal ganglion cells (RGCs) of apoptosis index in Wistar glaucoma models, as well as the relationship between IOP and RGC apoptosis index. Twelve Wistar glaucoma models were divided into two groups for experimental research with a pretest–posttest and posttest-only. The treatment group got oral administration of Mirtogenol 12.3 mg twice a day for 2 weeks, whereas the control group received a placebo in the same way. Apoptotic index and IOP were evaluated both before and after the intervention. A parametric independent t-test was used to determine the difference between groups, and a parametric paired t-test was used to determine the difference within groups. The results showed that the RGC apoptosis index in treatment groups was considerably less when compared to control groups (P < 0.001). In the treatment group, the IOP is decreased compared to the control group (mean difference: −12.67 ± 3.79 vs. 0.69 ± 4.64, respectively, P = 0.002). A significant and solid correlation was found between IOP and RGC apoptosis index (R = 0.884, P < 0.001). Thus, Mirtogenol supplementation is expected to be used to prevent glaucoma progression.
COVID-19 in third trimester of pregnancy
Authors: Yadiki JosnaVinutha , Ali Alftaikhah Sultan Abdulkarim 
Published: August 2023

ABSTRACT
The COVID-19 pandemic disease, which affects the respiratory system and produces flu-like symptoms, is caused by the SARS-CoV-2 virus. It is transmitted by close contact, oronasal secretions, or droplets. In general, pregnant individuals are at increased risk than nonpregnant individuals for developing serious SARS-CoV-2 virus-related illnesses, particularly during the third trimester. Despite the lack of research on COVID-19-infected pregnant mothers, this review article has discussed the clinical and laboratory characteristics and impact of COVID-19 on delivery, management, and vaccination of pregnant individuals with COVID-19 infection.
Utilization of local therapeutic food in preventing and treating nutrition problems in the dry land area of the islands of east nusa tenggara province
Authors: Picauly Intje , Nur Marselinus Laga , Marni Marni , Kale Esryk Indriyani 
Published: August 2023

ABSTRACT
The research aims to produce a local Pemberian makanan tambahan (PMT) biscuit formula that is nutritious, acceptable and has a good shelf life. Experimental research with RAL design used two factors and two treatments, namely the addition of anchovy flour (20% and 30%) and moringa leaf flour (20% and 30%) to 100 g of corn flour. The research was conducted in April–November 2022 with an analysis of nutritional content, and acceptability. Data were processed using SPSS with a statistical test One Way analysis of variance Test. The results of the analysis showed that the P4 product had a higher nutritional content difference, namely: 17.976 g of protein; fat 20.106 g; carbohydrates 60.644 g; minerals 3.632 μg; water content 3.999 aw; and energy 490.9 kcal with acceptance scores: Like-really like for 7 days at room temperature without standard packaging. Each serving portion for children of 2 pieces of biscuits or as much as 25 g/day gets a protein nutritional intake of 2.26 g or 11.3% of the Recommended dietary allowance (RDA); Fat of 2.66 or 5.9% of the RDA; Carbohydrates are 14.3 or 6.7% of the RDA and Energy is 615.23 kcal or 45.6% of the RDA. Product combination of 100 g of corn flour; 20 g of moringa flour; and 20 g of anchovy flour into the local therapeutic food “Iman” biscuit formulation which is very popular.
Clinical Profile of Human Immunodeficiency Virus Sero-Positives Attending Integrated Counselling and Testing Center in District Aligarh, Uttar Pradesh
Authors: Singh Rajende , Srivastava Abhay , Fatima Nazish , Shammem Mohammed , Shukla Indu 
Published: August 2023

Background:
Human immunodeficiency virus (HIV) seems to be a major public health challenge for all over the world, especially in developing countries such as India.

Objective:
The objective of the study was to study the sociodemographic profile of people living with HIV/acquired immune deficiency syndrome (AIDS) attending a standalone Integrated Counseling and Testing Centre (ICTC) at Jawaharlal Nehru Medical College and Hospital Aligarh in Uttar Pradesh.

Materials and Methods:
A record-based study was carried out among the HIV-positive patients who were attending the ICTC at Jawaharlal Nehru Medical college, AMU, Aligarh.

Results:
Prevalence of HIV infection was found to be 5.04% in and around Aligarh region. Males were more commonly affected than females with a ratio of 1.6:1. Majority of HIV-positive patients (35.82%) belonged to 25–34 years of age group. Most common clinical presentation was fever (46.9%) among HIV-positive patients, followed by weight loss (36.88%) and diarrhea (32.55%). Sexual transmission (61.19%) was the most common route of HIV transmission seen in our study. Most of the patients had a baseline CD4 count level below 200/μl.

Conclusion:
Majority of HIV/AIDS study subjects were from the economically productive age group. Education level, occupation, socioeconomic status, and marital status were found to be statistically associated. Practice of heterosexuality is the most common mode of transmission. Most of the patients reported at an early phase of disease.
A Cross-Sectional Study to Assess the Knowledge, Attitude, and Practices Regarding Contraceptive Methods among Reproductive Age Group Females
Authors: Sharma Saloni , Srivastava Abhay , Semwal Jayanti , Vyas Shaili , Sharma Neha 
Published: August 2023

Background:
Contraceptive methods play a vital role in family planning and has been established a cornerstone in reducing maternal and infant mortality rate. Family planning is encouraged as a tool to address the reproductive health needs of men and women, as well as the pivotal problem in regard to rapid population increase. The total fertility rate in Uttarakhand is 2.1 children per woman with couple protection rate of 53%, according to National Family Health Services.

Aims and Objectives:
We aimed to assess the knowledge regarding contraceptives and its usage among married women of reproductive age group in urban area.

Materials and Methods:
The study was a cross-sectional study using a quantitative survey questionnaire of duration 5 months. Women in reproductive age-group (15–45 years) were included in the study. A total of 102 study participants were enrolled.

Results:
Mean ± standard deviation of study participants was 29.09 ± 5.04. "Knowledge" questions had over 90% of correct responses. The attitude of study participants toward contraceptive usage was mostly favorable. Contraception usage practice was fairly good.

Conclusion:
There is a need to promote positive attitude among the general public so that they can create an environment to raise awareness among the general public regarding contraception.
Persistent suffering: Living experiences of patients with rare disease: An interpretative phenomenological study
Authors: Rezaei Fatemeh , Sanagoo Akram , Peyrovi Hamid , Jouybari Leila 
Published: August 2023

BACKGROUND:The low prevalence of rare diseases has caused the need for studies in this field to be neglected. Regardless of the prevalence of rare diseases, many people around the world have to live with the medical, psychological, and social consequences of their condition. Individuals with rare diseases may face challenges that are different from those experienced in more common medical conditions. The life experiences of patients with rare diseases have not been sufficiently investigated. The purpose of this study was to discover the meaning of living as a person with a rare disease.MATERIALS AND METHODS:This interpretative phenomenological study was conducted in 2021–2022 on 10 patients with one of the rare diseases (registered in the Atlas of Rare Diseases of Iran). Based on purposeful sampling, people with rare diseases living in Mazandaran, Golestan, and Tehran provinces were invited to participate in the study. Data collection was done using open and semi-structured interviews. The research question was exploring understanding the experience and meaning of life as a person with a rare disease. Van Manen's interpretive phenomenological approach was used to analyze the data, and the criteria of validity, transferability, and verifiability were used to ensure the trustworthiness of the research.RESULTS:The five main themes “permanent suffering, such as a bird in a cage, rejection, immersion in the whirlpool of thoughts, losing the feeling of life”, and 10 sub-themes “nightmare, giving up, deprivation, limitation, worthlessness, being stigmatized, dark vision, confusion, continuous regret, and inferiority feeling” were extracted.CONCLUSION:The results of this study show that the suffering of the disease casts a shadow on all aspects of a patient's life with a rare disease. The effects of illness, disability, limitations, and exclusions had created a human being in a cage, whose right to live like others has been denied.
Uncertainty and its related coping strategies in systemic lupus erythematosus. Life in the fog
Authors: Mazhariazad Fereshteh , Dianati Mansour , Taghadosi Mohsen , Zamani Batool 
Published: August 2023

BACKGROUND:
One of the most prevalent problems of patients with systemic lupus erythematosus (SLE) is the uncertainty over an indefinite future. Uncertainty has significant effects on quality of life. The aim of this study was to explore uncertainty and personal strategies to cope with it among patients with SLE.

MATERIALS AND METHODS:
This qualitative study was conducted in 2020–2021 using conventional content analysis. Participants were 21 patients with SLE who were purposefully selected from rheumatology clinics in Kashan, Kerman, and Bandar Abbass in Iran. Data collection was performed using face-to-face, in-depth, semi-structured interviews and was continued up to data saturation. Data were analyzed concurrently with data collection through conventional content analysis approach proposed by Graneheim and Lundman.

RESULTS:
Two main themes, namely, “life in the fog” and “attempt to find peace” emerged from patients' experiences of illness uncertainty of SLE. Life in the fog included three main categories of “perception of threat to health”, “challenge of doubt and certainty,” and “indefinite future.” Attempt to find peace included three main categories of “spirituality,” “reflection,” and “attempt to acquire SLE-related knowledge.

CONCLUSIONS:
Uncertainty is a major psychological stress for patients with SLE. Healthcare providers should therefore consider the challenges and concerns faced by patients and, through utilizing appropriate training and communicational practices, plan interventions and strategies to empower patients for coping with uncertainty.
Evaluation and comparison of knowledge translation patterns in selected countries with Iran: A comparative study
Authors: Mansouri Arani Mohammad Reza , Zamanzadeh Vahid , Rassouli Maryam , Valizadeh Leila 
Published: August 2023

BACKGROUND:
One of the main issues related to the inefficiency of the health system is the lack of sufficient communication between researchers and health policymakers regarding the exchange of the latest findings and the use of inappropriate evidence to manage cases. The knowledge translation removes this disconnect.

MATERIALS AND METHODS:
In this comparative study, to obtain appropriate data on the status of knowledge translation, refer to the databases of reputable centers and governments and the knowledge translation models were reviewed in the title of main articles, abstracts, guidelines, and reports of reputable international organizations between 2005 and 2020. The origin of the models was determined, then the countries with the largest number of models were selected and analyzed using Walt and Gilson's “Policy Triangle framework in four dimensions: context, content, process, and actors.”

RESULTS:
All the three countries have politically, socially, and economically made knowledge translation one of their policy priorities. Iran's centralized health system is a major obstacle. The USA and Canada have clear strategies and coherent and practical infrastructures that implement the knowledge translation in the form of operational plans. In contrast, in Iran, it has been enough to establish the knowledge translation centers at the level of universities and knowledge translation websites. In Iran, the Ministry of Health and universities of medical sciences play a direct role, but in Canada, they also use knowledge broker to apply knowledge.

CONCLUSION:
Iran is building capacity in the field of knowledge translation. That the implementation of interventions with the cooperation of macro policymakers can strengthen it.
Effect of couples 'online training on maternal-fetal attachment in pregnant women
Authors: Abasi Elieh , Borghei Narjes Sadat , Goli Shahrbanoo , Farjamfar Maryam , Keramat Afsaneh 
Published: August 2023

BACKGROUND:
Due to the importance of maternal fetal attachment (MFA) in women mental health improvement and considering the fathers' role in MFA promoting, this study conducted to investigate the effect of couple education on maternal fetal attachment.

MATERIALS AND METHOD:
This randomized controlled trial was conducted on 100 pregnant women and their husbands referred to six health centers in Sari from May to June 2021. The sampling method was stratified random sampling. Data collection tools included demographic information form and the Cranley MFA Scale with 24 questions. The intervention group took part in four session's weekly training about spouse support, attachment behaviors, and gender preference of parents, while the control group received only the routine antenatal care. Both groups completed Cranley's questionnaire before and 4 weeks after the intervention. Data were analyzed using Chi-square test, Fisher's exact test, paired and independent t-test by SPSS 21.

RESULTS:
MFA mean scores, pre-training and post-training in intervention group were 3.27 (0.54) and 3.75 (0.42), respectively; in the control group, were, 3.24 (0.49) and 3.21 (0.48). There was a significant difference between the two groups' MFA mean scores after intervention (P < 0.001).

CONCLUSION:
The findings of this study revealed that couple training regarding spouse support, attachment behaviors, and gender preference during pregnancy can promotes MFA even online training.
The relationship between perceived stress and emotional intelligence in Moroccan nursing students
Authors: Ksiksou Jamal , Maskour Lhoussaine , Alaoui Smail 
Published: August 2023

BACKGROUND:
Nursing students are subjected to many stressors during their clinical practicums. Emotional intelligence (EI) could act as a real stress regulator. In this perspective, we sought to study the relationship between stress and EI in a sample of Moroccan nursing students.

MATERIALS AND METHODS:
This study was conducted using the descriptive correlational method. The statistical population consisted of the nursing students of the Higher Institute of Nursing Professions and Health Techniques of Tetouan in Morocco during the academic year 2021-2022. Among them, 146 participants were selected on the basis of simple random sampling. Participants completed a self-administered questionnaire addressing sociodemographic factors, perceived stress (the Perceived Stress in Clinical Practice Scale), and emotional intelligence (Wong and Law Emotional Intelligence Scale test). Descriptive statistics were used and Pearson's correlation coefficient was applied to assess the correlation between stress and EI, and to compare them according to socio-demographic characteristics. A linear regression analysis was calculated to analyze the effect of independent variables on perceived stress and EI. For the analysis, a level of 0.05 was chosen.

RESULTS:
The overall mean age of the students was 20.02 ± 1.12 years. Participants had moderate levels of perceived stress (M = 2.42 ± 0.77) and high levels of EI (M = 3.79 ± 1.09). A significant positive correlation between perceived stress and EI was found (r = 0.741, P
< 0,05). The regression model shows that EI, education level, and clinical practice setting can explain changes in perceived stress levels and are effective and significant factors (P < 0,001).

CONCLUSION:
EI has been shown to be a protective factor against stress in nursing students. Those with well-developed EI have lower levels of stress. Therefore, it is suggested that a mindfulness-based training program be incorporated into the nursing curriculum to develop emotional skills and combat stress in students.
The “Know Your Lemons” Tools: A strategy to improve breast cancer warning signs recognition in Malaysia
Authors: Mei Yen Mary Chan , Islam Tania , Ellsworth-Beaumont Corrine , Dhillon Sarinder Kaur , Ganggayah Mogana Darshini , Taib Nur Aishah 
Published: August 2023

BACKGROUND:
Breast cancer (BC) is the most common cancer in Malaysia, with many diagnosed at late stages. The “Know Your Lemons” (KYL) visual educational tools were developed by KYL Foundation. This study aimed to evaluate participants' confidence levels and perceived knowledge in identifying BC symptoms before and after exposure to KYL tools.

MATERIALS AND METHODS:
A cross-sectional study was carried out among 788 participants in three KYL health campaigns from 2017 to 2020. Perceived knowledge (a 5-item Likert scale was used, zero means “very poor” and 4 means “excellent knowledge”) and confidence in identifying BC symptoms were studied. A Wilcoxon Matched-Paired Signed-Rank Test was performed to assess the perceived knowledge.

RESULTS:
There was a significant improvement in the perceived knowledge Mean (±SD) score (2.84 ± 1.02) versus (4.31 ± 0.66) before and after the campaign (P < 0.01). About 95.6% agreed that the language used in KYL materials was clear and understandable, 89.8% agreed it is acceptable in Malaysian culture, and 80% felt more confident in identifying BC symptoms. Therefore, 90.8% had the intention of breast self-examination and 90.8% would consult a doctor if symptomatic. The majority (92.7%) agreed that the KYL tools clarified the BC tests needed.

CONCLUSION:
The KYL tools enhanced perceived BC symptom recognition knowledge and confidence levels.
Predictors and influencing factors of emotional intelligence among nurses in the North East England, United Kingdom
Authors: Awe Ayodele O. , David-Olawade Aanuoluwapo C. , Ayodele-Awe Iyanuoluwa , Feng Haibo , Odetayo Aderonke , Afolalu Temitope D. , Ladan Henrietha , Olawade David B. 
Published: August 2023

BACKGROUND:
Recognising that high levels of emotional intelligence (EI) are required for involvement in the nursing practice, this study was conducted to assess the traits of emotional intelligence, perception of emotional intelligence and factors associated with emotional intelligence among nursing teams in Northeast England.

MATERIALS AND METHODS:
For this descriptive cross-sectional study, a concurrent mixed method was employed (qualitative and quantitative method) using a convenience sampling technique. Data were obtained from one hundred and ten (110) staff nurses practicing with the National Health Service via a validated semi-structured questionnaire and in-depth interview. Data collected through questionnaires (online- Google form link) were retrieved via Ms excel spreadsheet and then imported to Statistics Package for Social Sciences (SPSS) version 25 for analyses. Interviews recorded were transcribed word for word as Nvivo software (version 12) was utilised for thematic analysis and rapid analysis was also adopted to validate the responses.

RESULTS:
Majority (77%) of the respondents were females, and about half (46%) have work experience between one to five years. The mean emotional intelligence trait score for each domain was self-awareness (20.20), self-regulation (38.15), self-motivation (20.54), empathy (18.78), and social skills (29.60), as 82% of the nurses had high emotional intelligence trait. There was a statistically significant relationship between empathy, and race of the respondents (P = 0.040). Also, from the qualitative data; cultural differences, personality traits, self-care, family support, and organisational structure are key predictors of emotional intelligence traits among nurses.

CONCLUSION:
Enhancing emotional intelligence traits among nursing teams is significant, as it may serve as an intervention strategy to manage changes and still increase level of morale and productivity among nurses. Hence, creating a more supportive environment, encouragement from team leads or supervisors, and training on stress management strategies can help to reduce burnout, anxiety and stress in nurses.
The effects of breast milk odor on the physiological and behavioral responses caused by venipuncture pain in term infants: A clinical trial study
Authors: Asadian Asma , Shirinzadeh-Feizabadi Atefeh , Amiri-Shadmehri Elaheh , Yaghoobi Hamideh 
Published: August 2023

BACKGROUND:
Pain management is very important for infants who are unable to express it verbally. Pain control is one of the nursing actions and part of their duties. This study attempted to determine the effects of breast milk odor on the physiological and behavioral responses caused by venipuncture pain in full-term infants at an educational hospital.

MATERIALS AND METHODS:
This randomized clinical trial study was carried out on 3–5 days' term and healthy babies with a gestational age of 34 weeks and later in the 9-Day Hospital of Torbet Heydariyeh, Iran, 2021. The sample size, taking into account the possibility of a 10% dropout of samples included 20 babies for each group and a total of 40 babies were selected by convenience sampling. To collect data, a checklist of demographic characteristics, a registration form for physiological responses, and the modified behavioral pain scale were used.

RESULTS:
The results of this study showed that breast milk odor has a positive effect on behavioral responses (P < 0.001) and also a significant relationship was observed between the effects of breast milk odor and physiological responses percentage of oxygen uptake and pulse (P < 0.001). However, no significant relationship was observed between breast milk odor and breathing variables (P > 0.05).

CONCLUSIONS:
According to the results, olfactory stimulation with breast milk during venous blood sampling showed positive effects on physiological responses and pain reduction in infants. Therefore, it is recommended to use soothing stimuli such as the smell of breast milk during painful procedures in babies.