bluuebunny/crossref_metadata_2025_split huggingface dataset:
Automatic air pollution monitoring and corporate environmental disclosure: a quasi-natural experiment from China
Authors: Chen Hanwen , Liu Siyi , Yang Daoguang , Zhang Di 
Published: April 2023

Purpose
This study aims to investigate the role of regional environmental transparency on corporate environmental disclosure.

Design/methodology/approach
This study uses the introduction of a nationwide automated air pollution monitoring network in China as a quasi-natural experiment and employs regression analysis. Robustness checks, including parallel trend test and placebo test, are performed to test the robustness of the results.

Findings
Sharing air pollution data with the public can improve corporate environmental disclosure. Firms with poorer environmental, social and governance (ESG) performance prefer to disclose less informative information after the automated network is implemented compared with firms with better ESG performance. The relationship between information sharing and corporate environmental transparency is more pronounced when local air pollution is severer, firms face stronger investor scrutiny and firms are from heavily polluting industries. The mechanism tests suggest the automated system can draw public environmental attention and improve governments’ aspiration for environmental governance. Finally, corporate environmental disclosure can reduce stock price crash risk and cost of equity.

Practical implications
Real-time pollution data reporting is an important solution to raising public environmental awareness and then enhancing the effectiveness of pollution control.

Social implications
This study has implications for policy-making regarding environmental governance and environmental disclosure.

Originality/value
This study confirms that pollution information transparency can motivate firms to increase environmental disclosure.
Why the new way of working requires a new era of employee benefits engagement
Authors: Hunter Andreas 
Published: April 2023

Purpose
The purpose of this paper is to inform employers how to engage their employees with their benefits strategy.

Design/methodology/approach
The author draws on personal experience and observations from the field relating to employee engagement strategies as workers are increasingly working remotely.

Findings
Despite changes in the workplace wrought by the pandemic, the fundamental need to emotionally connect with the employee remains – but it requires to be done in a slightly different way.

Originality/value
The article offers readers valuable insight gleaned from extensive experience and client engagement.
Plant–soil feedbacks in a diverse grassland: Soil remembers, but not too much
Authors: Kuťáková Eliška , Mészárošová Lenka , Baldrian Petr , Münzbergová Zuzana , Herben Tomáš 
Published: April 2023

Abstract

Plant–soil feedbacks (PSFs) are one of the major drivers of species coexistence in highly dynamic and low‐diversity communities, such as early successional stands or agricultural systems. However, in stable and species‐rich communities, PSFs are much more complex because of numerous species interactions. In this study, we aimed to reveal if PSFs of a dominant species can be detected within a diverse plant community and to what extent they can be influenced by the effects of co‐occurring species.

We investigated PSFs between a dominant grass, Festuca rubra, and three other species from a species‐rich mountain grassland, taking advantage of the 18‐year field removal experiment. We tested whether such a long‐term presence/absence of Festuca can shape the feedback of the grassland community and whether these effects prevail in the lower soil layer, where Festuca roots are relatively more abundant, compared to the upper soil layer. We evaluated how experimentally induced soil legacies of Festuca in a pot experiment are modified by subsequently grown plants, both at the level of plant responses and changes in abiotic and biotic soil properties.

At the level of the entire community, the soil legacies of the dominant Festuca were not detectable. However, the responses of the plants differed between the soil samples from the upper and lower soil layer. The pot experiment showed that the soil legacies of subsequently growing plants interact, influencing soil properties as well as plant responses to these altered soils. Generally, we found a stronger signal of the most recent conditioning, although the effect of the first conditioning plant was still detectable in many of the measured variables. Plant biomass in the feedback phase was mainly linked to the levels of plant‐available soil nitrogen, although it was also affected by the composition of microbial communities.

Synthesis. We showed that plant‐induced soil legacies can be altered by legacies of co‐occurring species, complicating plant–soil feedbacks in diverse communities. Despite the detectable legacy effects on final plant biomass, in the short term, plant growth responds more strongly to the levels of available nutrients. We also highlight the vertical distribution of plant–soil feedbacks.
Letter: disentangling the role of redox‐active compounds in the development of inflammatory bowel diseases – moving towards causal associations
Authors: Geertsema Sem , van Goor Harry , Dijkstra Gerard , Faber Klaas Nico , Bourgonje Arno R. 
Published: April 2023

LINKED CONTENTThis article is linked to Chen et al papers. To view these articles, visit https://doi.org/10.1111/apt.17392 and https://doi.org/10.1111/apt.17468
Letter: disentangling the role of redox‐active compounds in the development of inflammatory bowel diseases—moving towards causal associations. Authors' reply
Authors: Chen Jie , Ruan Xixian , Yuan Shuai , Theodoratou Evropi , Satsangi Jack , Li Xue 
Published: April 2023

LINKED CONTENTThis article is linked to Chen et al papers. To view these articles, visit https://doi.org/10.1111/apt.17392 and https://doi.org/10.1111/apt.17455
Buspirone for early satiety and symptoms of gastroparesis: A multi‐centre, randomised, placebo‐controlled, double‐masked trial (BESST)
Authors: Parkman Henry P. , Yates Katherine P. , Sarosiek Irene , Bulat Robert S. , Abell Thomas L. , Koch Kenneth L. , Kuo Braden , Grover Madhusudan , Farrugia Gianrico , Silver Paul , Abdullah Amirah , Maurer Alan H. , Malik Zubair , Miriel Laura A. , Tonascia James , Hamilton Frank , Pasricha Pankaj J. , McCallum Richard W. ,   for the NIDDK Gastroparesis Clinical Research Consortium
Published: April 2023

SummaryBackgroundPatients with gastroparesis and related disorders have symptoms including early satiety, postprandial fullness and bloating. Buspirone, a 5‐HT1 receptor agonist, may improve fundic accommodation.AimTo determine if buspirone treatment improves early satiety and postprandial fullness in patients with symptoms of gastroparesis.MethodsThis 4‐week multi‐centre clinical trial randomised patients with symptoms of gastroparesis and moderate‐to‐severe symptoms of fullness (Gastroparesis Cardinal Symptom Index [GCSI] early satiety/postprandial fullness subscore [ES/PPF]) to buspirone (10 mg orally) or placebo three times per day. The primary outcome was a change in the ES/PPF from baseline to 4 weeks. The primary analysis was per protocol intention‐to‐treat ANCOVA of between‐group baseline vs. 4‐week differences (DoD) in ES/PPF adjusted for baseline ES/PPF. Results are reported using both nominal and Bonferroni (BF) p values.Results and conclusionsNinety‐six patients (47 buspirone, 49 placeboes; 92% female, 50% delayed gastric emptying, 39% diabetic) were enrolled. There was no between‐groups difference in the 4‐week ES/PPF primary outcome: −1.16 ± 1.25 (SD) on buspirone vs −1.03 ± 1.29 (SD) on placebo (mean DoD: −0.11 [95% CI: −0.68, 0.45]; p = 0.69). Buspirone performed better than placebo in patients with severe‐to‐very severe bloating at baseline compared to patients with none to moderate: (ES/PPF DoD = −0.65 vs. 1.58, pTX*GROUP = 0.003; pBF = 0.07). Among individual GCSI symptoms, only bloating appeared to improve with buspirone vs. placebo.ConclusionsPatients with moderate‐to‐severe early satiety/postprandial fullness and other symptoms of gastroparesis did not benefit from buspirone treatment to improve the ES/PPF primary outcome compared with placebo. There was a suggestion of the benefit of buspirone in patients with more severe bloating.Trial Registration: ClinicalTrials.gov NCT0358714285.
Population‐attributable risk of modifiable lifestyle factors to hepatocellular carcinoma: The multi‐ethnic cohort
Authors: Zhou Kali , Lim Tiffany , Dodge Jennifer L. , Terrault Norah A. , Wilkens Lynne R. , Setiawan V. Wendy 
Published: April 2023

SummaryBackground and AimsLifestyle factors are well associated with risk of hepatocellular carcinoma (HCC). However, the impact of reducing adverse lifestyle behaviours on population‐level burden of HCC is uncertain.MethodsWe conducted prospective analysis of the population‐based multi‐ethnic cohort (MEC) with linkage to cancer registries. The association of lifestyle factors (smoking, alcohol, diet quality assessed by alternate Mediterranean diet score, coffee drinking, physical activity and body mass index) with HCC incidence was examined using Cox regression. Population‐attributable risk (PAR, %) for the overall, lean and overweight/obese populations was determined.ResultsA total of 753 incident cases of HCC were identified in 181,346 participants over median follow‐up of 23.1 years. Lifestyle factors associated with elevated HCC risk included former/current smoking, heavy alcohol use, poor diet quality, lower coffee intake and obesity, but not physical activity. The lifestyle factor with highest PAR was lower coffee intake (21.3%; 95% CI: 8.9%–33.0%), followed by current smoking (15.1%; 11.1%–19.0%), obesity (14.5%; 9.2%–19.8%), heavy alcohol use (7.1%; 3.5%–10.6%) and lower diet quality (4.1%; 0.1%–8.1%). The combined PAR of all high‐risk lifestyle factors was 51.9% (95% CI: 30.1%–68.6%). A higher combined PAR was observed among lean (65.2%, 26.8%–85.7%) compared to overweight/obese (37.4%, 11.7%–58.3%) participants. Adjusting for viral hepatitis status in a linked MEC‐Medicare dataset resulted in similar PAR results.ConclusionsModifying lifestyle factors, particularly coffee intake, may have a substantial impact on HCC burden in diverse populations, with greater impact among lean adults. Diet and lifestyle counselling should be incorporated into HCC prevention strategies.
The Contextualized Emotion Regulation Survey for Adolescents (CERSA): How does emotion regulation vary according to context?
Authors: Fombouchet Yoann , Lannegrand Lyda , Lucenet Joanna 
Published: April 2023

AbstractRecent models of emotion regulation (ER) highlight the need to construct tools that assess ER in different contexts. This paper describes the development and validation of the Contextualized Emotion Regulation Survey for Adolescents (CERSA). This questionnaire assesses ER strategies and abilities in three situations that elicit specific emotions (i.e. sadness, fear and anger). Data were collected from a sample of 840 adolescents who completed the CERSA (M
age = 14.75; SD
age = 1.61) and another of 314 adolescents who completed the CERSA, the CERQ and the SLWS (M
age = 13.63; SD
age = 0.85). Results confirmed the expected structure in all situations as well as construct and external validity. Furthermore, correlations between latent factors and gender differences in ER strategies and abilities were often situation dependant. Mean levels of ER strategies and abilities varied according to the situation. These results provide empirical support for ER flexibility and polyregulation in adolescence.
The impact of foreign direct investment on innovation at domestic firms: Evidence from the deregulation of foreign investment in China
Authors: Liu Yan , Wang Xuan 
Published: April 2023

AbstractThis paper studies the impact of foreign direct investment (FDI) on innovation by domestic firms in China. A difference‐in‐difference estimation strategy yields causal evidence by exploiting China's deregulation of FDI in 2002. Analysis of a matched firm–patent data set from 1998 to 2007 shows that both the quantity and quality of innovation by domestic firms benefited from the presence of FDI. Emphasizing the importance of knowledge spillover from FDI in similar technology domains, the authors examine the role of horizontal FDI and FDI in technologically close industries—those sharing similar technology domains. Findings show that the latter generates much more substantial positive spillover than the former. The paper also shows that knowledge spillover from FDI in similar technology domains is not driven by input–output linkages. In addition, the spillover effect is stronger in cities with higher human capital stock and firms with higher absorptive capacity.
Derivation of new pluripotent stem cells from human extended pluripotent stem cells with formative features and trophectoderm potential
Authors: Zhu Pinmou , Zhang Bohang , Sun Ruiqi , Wang Jiachen , Liu Zhaode , Liu Xiaorui , Yan Min , Cui Yiqiang , Sha Jiahao , Yuan Yan 
Published: April 2023

AbstractPrevious studies have demonstrated the existence of intermediate stem cells, which have been successfully obtained from human naive pluripotent stem cells (PSCs) and peri‐implantation embryos. However, it is not known whether human extended pluripotent stem cells (hEPSCs) can be directly induced into intermediate stem cells. Moreover, the ability of extra‐embryonic lineage differentiation in intermediate stem cells has not been verified. In this issue, we transformed hEPSCs into a kind of novel intermediate pluripotent stem cell resembling embryonic days 8–9 (E8‐E9) epiblasts and proved its feature of formative epiblasts. We engineered hEPSCs from primed hPSCs under N2B27‐LCDM (N2B27 plus Lif, CHIR, DiH and MiH) conditions. Then, we added Activin A, FGF and XAV939 to modulate signalling pathways related to early humans' embryogenesis. We performed RNA‐seq and CUT&Tag analysis to compare with AF9‐hPSCs from different pluripotency stages of hPSCs. Trophectoderm (TE), primordial germ cells‐like cells (PGCLC) and endoderm, mesoderm, and neural ectoderm induction were conducted by specific small molecules and proteins. AF9‐hPSCs transcription resembled that of E8‐E9 peri‐implantation epiblasts. Signalling pathway responsiveness and histone methylation further revealed their formative pluripotency. Additionally, AF9‐hPSCs responded directly to primordial germ cells (PGCs) specification and three germ layer differentiation signals in vitro. Moreover, AF9‐hPSCs could differentiate into the TE lineage. Therefore, AF9‐hPSCs represented an E8‐E9 formative pluripotency state between naïve and primed pluripotency, opening new avenues for studying human pluripotency development during embryogenesis.
Time requirements for perioperative glucose management using fully closed‐loop versus standard insulin therapy: A proof‐of‐concept time–motion study
Authors: Roos Jonathan , Schürch Daniel , Frei Andreas , Lagger Sophie , Schwenkglenks Matthias , Vogt Andreas , Herzig David , Bally Lia 
Published: April 2023

AbstractAimsTo compare the time required for perioperative glucose management using fully automated closed‐loop versus standard insulin therapy.MethodsWe performed a time–motion study to quantify the time requirements for perioperative glucose management with fully closed‐loop (FCL) and standard insulin therapy applied to theoretical scenarios. Following an analysis of workflows in different periods of perioperative care in elective surgery patients receiving FCL or standard insulin therapy upon hospital admission (pre‐ and intra‐operatively, at the intermediate care unit and general wards), the time of process‐specific tasks was measured by shadowing hospital staff. Each task was measured 20 times and its average duration in combination with its frequency according to guidelines was used to calculate the cumulative staff time required for blood glucose management. Cumulative time was calculated for theoretical scenarios consisting of elective minor and major abdominal surgeries (pancreatic surgery and sleeve gastrectomy, respectively) to account for the different care settings and lengths of stay.ResultsThe FCL insulin therapy reduced the time required for perioperative glucose management compared to standard insulin therapy, across all assessed care periods and for both perioperative pathways (range 2.1–4.5). For a major abdominal surgery, total time required was 248.5 min using FCL versus 753.9 min using standard insulin therapy. For a minor abdominal surgery, total time required was 68.6 min and 133.2 min for FCL and standard insulin therapy, respectively.ConclusionsThe use of fully automated closed‐loop insulin delivery for inpatient glucose management has the potential to alleviate the workload of diabetes management in an environment with adequately trained staff.
‘Is Insulin Right for Me?’: Web‐based intervention to reduce psychological barriers to insulin therapy among adults with non‐insulin‐treated type 2 diabetes—A randomised controlled trial
Authors: Holmes‐Truscott Elizabeth , Holloway Edith E. , Lam Benjamin , Baptista Shaira , Furler John , Hagger Virginia , Skinner Timothy , Speight Jane 
Published: April 2023

AbstractAimsTo test ‘Is Insulin Right for Me?’, a theory‐informed, self‐directed, web‐based intervention designed to reduce psychological barriers to insulin therapy among adults with type 2 diabetes. Further, to examine resource engagement and associations between minimum engagement and outcomes.MethodsDouble‐blind, two‐arm randomised controlled trial (1:1), comparing the intervention with freely available online information (control). Eligible participants were Australian adults with type 2 diabetes, taking oral diabetes medications, recruited primarily via national diabetes registry. Exclusion criteria: prior use of injectable medicines; being ‘very willing’ to commence insulin. Data collections were completed online at baseline, 2‐week and 6‐month follow‐up. Primary outcome: negative insulin treatment appraisal scale (ITAS) scores; secondary outcomes: positive ITAS scores and hypothetical willingness to start insulin. Analyses: intention‐to‐treat (ITT); per‐protocol (PP) examination of outcomes by engagement. Trial registration: ACTRN12621000191897.ResultsNo significant ITT between‐arm (intervention: n = 233; control: n = 243) differences were observed in primary (2 weeks: Mdiff [95% CI]: −1.0 [−2.9 to 0.9]; 6 months: −0.01 [−1.9 to 1.9]), or secondary outcomes at either follow‐up. There was evidence of lower Negative ITAS scores at 2‐week, but not 6‐month, follow‐up among those with minimum intervention engagement (achieved by 44%) compared to no engagement (−2.7 [−5.1 to −0.3]).ConclusionsCompared to existing information, ‘Is insulin right for me?’ did not improve outcomes at either timepoint. Small intervention engagement effects suggest it has potential. Further research is warranted to examine whether effectiveness would be greater in a clinical setting, following timely referral among those for whom insulin is clinically indicated.
Use of insulin pumps and closed‐loop systems among people living with diabetes: A narrative review of clinical and cost‐effectiveness to enable access to technology and meet the needs of payers
Authors: Jendle Johan , Reznik Yves 
Published: April 2023

AbstractThe use of continuous subcutaneous insulin infusion (CSII) via insulin pumps is today considered standard of care for type 1 diabetes (T1D). Closed‐loop systems combining continuous glucose monitoring with automated algorithm‐driven insulin delivery have been shown to be safe and efficacious in randomized controlled trials and real‐life studies in both paediatric and adult participants with T1D. Implementation of hybrid closed‐loop (HCL) systems has shown incremental effectiveness, with further reduction of hypoglycaemia and hyperglycaemia. Although less extensively studied in type 2 diabetes (T2D), insulin pumps have demonstrated their effectiveness in glucose control, along with a reduction in need for insulin and a neutral effect on weight. Recent studies have also shown promising results with the use of HCL systems in T2D. Cost‐effectiveness studies in both T1D and T2D have shown that pump use is cost‐effective in several countries, leading to improvements in quality‐adjusted life‐years. Insulin pumps are currently reimbursed for T1D in many European countries, but in only a few for individuals with T2D. HCL systems are to be evaluated in future trials performed in T2D to compare their incremental efficacy and cost‐effectiveness in comparison with available intensification tools which include multiple daily insulin injections, metformin, sodium‐glucose cotransporter‐2 inhibitors and glucagon‐like peptide‐1 receptor agonists. There is a need for updated guidelines for the use of CSII and HCL in individuals living with T2D based on the emerging evidence, with identification of and recommendations for the people who would benefit the most, which would eventually form a basis for reimbursement and health policies.
Old Man Saltbush mortality following fire challenges the resilience of post‐mine rehabilitation in central Queensland, Australia
Authors: McKenna Phillip B. , Ufer Natasha , Glenn Vanessa , Doley David , Phinn Stuart , Erskine Peter D. 
Published: April 2023

SummaryLandscape rehabilitation following mining is required to be resilient to disturbance impacts such as fire, drought and disease. As mining companies undergo the process of rehabilitation certification and mine closure, there are notable knowledge gaps on the ecological risks associated with mature rehabilitated landscapes, based largely on the assumption that rehabilitation is analogous to reference communities. However, the response to fire disturbance across a range of landscapes remains largely untested and in particular there is limited understanding of recovery traits of plant species that occur naturally or are commonly seeded into rehabilitation. In August 2018, a controlled fire was applied to 37 hectares of 12‐year‐old coal‐mine rehabilitation in central Queensland, Australia. We used a combination of (i) ground plot surveys and (ii) drone imagery to compare the vegetation response of burnt woody species to unburnt controls prior to, and for, two years following the fire. The survival of the most dominant shrub species found on the rehabilitation site was significantly impacted by the fire. Old Man Saltbush (Atriplex nummularia Lindl. subsp. nummularia) recorded significant post‐fire mortality, with ground surveys recording an average reduction of 89% of stems per hectare across the burnt site, while unburnt controls remained unchanged. The plot data analysis was supported with high spatial and temporal resolution drone imagery, classified using a Random Forest machine‐learning approach. Change analysis of these maps showed a significant decline of 82% in Old Man Saltbush plant density and 92% reduction in foliage cover following the fire. In addition, the mean canopy area of individual Old Man Saltbush shrubs reduced significantly from a pre‐fire mean of 11.3 to 4.8 m2 two years following the fire. A spatial proximity analysis showed that those individuals that survived the fire were located significantly closer to unburnt areas and bare spoil, indicating that discontinuous ground fuel loads can greatly improve the survivability of individuals. This study provides new evidence on the contested fire sensitivity of Old Man Salt bush and demonstrates the risk that future climate‐driven extreme events may have on the resilience of novel ecosystems.