bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subjectively intense odor does not affect dream emotions during rapid eye movement sleep
Authors: Okabe Satomi , Abe Takashi 
Published: June 2023

AbstractDreams experienced during rapid eye movement (REM) sleep have emotional features. Intervention methods for dream affectivity have recently garnered interest; we previously demonstrated that negative dreams were induced during REM sleep by exposure to favorable or familiar odors. However, the underlying mechanisms behind this phenomenon remain unclear. Thus, to address this gap, we investigated whether more intense odors could induce negative dreams, as odors tend to be perceived as more intense when they are preferred or familiar. Contrary to our hypothesis, the results of our study indicated that subjective intense odors did not induce negative dreams. We initially anticipated stronger odors to have a greater impact on dream emotionality, as they stimulate the brain more intensely. Notably, during arousal, weak odors tended to evoke a more potent olfactory response, while strong odors tended to produce a weaker response. To investigate whether this difference influenced the effects on dreams, we compared the respiratory activities of the strongly and weakly perceived odor groups; however, no significant differences were observed. Our findings suggest that subjectively perceived strong odors are unlikely to affect dream emotionality and may be processed differently than favorable or familiar odors.
Overwintering and breeding patterns of monarch butterflies (Danaus plexippus) in coastal plain habitats of the southeastern USA
Authors: Kendrick Michael R. , McCord John W. 
Published: June 2023

AbstractUnderstanding variability in species’ traits can inform our understanding of their ecology and aid in the development of management and conservation strategies. Monarch butterflies (Danaus plexippus) are native to the western hemisphere and are well-known for their long-distance migrations but have experienced significant population declines in recent decades. Here we use a 5-year capture-mark-recapture dataset to compare monarch distributions, mating activity, and larval host plant use between two coastal plain habitats in South Carolina, USA. We observed seasonally specific habitat use, with maritime habitats serving as overwintering areas while nearby inland swamps support significant breeding in spring, summer, and fall seasons due to an abundance of aquatic milkweed (Asclepias perennis). We also observed mating activity by fall migrating monarchs and their use of swallow-wort (Pattalias palustre) in the spring as an important larval host plant in maritime habitats. This phenology and habitat use of monarchs diverges from established paradigms and suggest that a distinct population segment of monarchs may exist, with significance for understanding the conservation status of monarch butterflies and associated habitats in eastern North America. Further research should explore how monarchs along the Atlantic coast of North America relate to other eastern monarch populations.
Energy metabolism and thermoregulation during sleep in young and old females
Authors: Seol Jaehoon , Kokudo Chihiro , Park Insung , Zhang Simeng , Yajima Katsuhiko , Okura Tomohiro , Tokuyama Kumpei 
Published: June 2023

AbstractCore body temperature (CBT) shows a diurnal rhythm, and the nocturnal decrease in CBT is blunted in older people. The physiological mechanisms responsible for the blunted nocturnal decrease in CBT in older people remain to be revealed. The aim of this study was to compare heat production and heat dissipation in young and old subjects during sleep, as assessed by indirect calorimetry and the distal–proximal temperature gradient (DPG) of skin temperature. A complete dataset of 9 young (23.3 ± 1.1 years) and 8 old (72.1 ± 2.5 years) females was analyzed. CBT and energy metabolism were monitored during sleep using an ingestible temperature sensor in a metabolic chamber maintained at 25 °C. Skin temperature was measured at proximal and distal parts of the body. CBT, distal skin temperature, and DPG in older subjects were higher than in young subjects. Protein oxidation was similar between the two groups, but fat oxidation was lower and carbohydrate oxidation was higher in old subjects compared to young subjects. On the other hand, energy expenditure was similar between the two age groups. Thus, the elevated CBT in older subjects was not attributed to deteriorated heat dissipation or enhanced heat production, suggesting an alternative explanation such as deteriorated evaporative heat loss in old subjects.
Stability bearing capacity of concrete filled steel tubular columns subjected to long-term load
Authors: Lai Xiuying , Gao Huabin , Yang Zhen , Zheng Juan , Chen Zhaoyu , Lin Fuming 
Published: June 2023

AbstractConcrete-filled steel tube (CFST) are commonly used in modern building and bridge applications. Despite their popularity, studies on the investigation of the influence of long-term load on the stability bearing capacity of such elements are scarce. This study investigates how the key parameters including slenderness ratio (λ), axial load ratio (m), and eccentricity ratio (e/r) affect the stability bearing capacity of a CFST column under sustained load. Twenty three CFST columns were fabricated to investigate the effect of long-term load on the stability bearing capacity. Fourteen specimens were subjected to constant compressive loading for 462 days and then tested for failure. The remaining 9 were companion load-free specimens. A three-stage finite element method was used to predict the stability bearing capacity after creep. The results indicate that the stability bearing capacity of CFST columns decrease after being subjected to long-term load. Both the experimental and numerical results indicated that the load of steel tube for long-term load specimens reaching up to the elastic–plastic and plastic process was lower than that of the load-free specimens. Moreover, the corresponding strain of the creep specimens was greater than that of the load-free specimens when the member reached the maximum load. Benchmarking analyses have shown that the creep reduction coefficient (kcr) proposed for CFST columns can be used to predict the reduction of stability bearing capacity after creep. Furthermore, a collected database comprising 49 CFST specimens subjected to long-term load was used to investigate the proposed formulae for kcr. The results show that the formulae were consistent with the experiment results.
A novel retinoic acid drug, EYE-502, inhibits choroidal neovascularization by targeting endothelial cells and pericytes
Authors: Shen Yaming , Xu Miao , Ren Ling , Li Xiumiao , Han Xiaoyan , Cao Xin , Yao Jin , Yan Biao 
Published: June 2023

AbstractChoroidal neovascularization (CNV) occurs in neovascular age-related macular degeneration (AMD) and often leads to permanent visual impairment. Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is the gold standard for the treatment of CNV. However, anti-VEGF treatment did not always cause vision improvement and sometimes had detrimental effects on normal retinal tissues. Herein, we identified a novel retinoic acid drug, EYE-502, which had great therapeutic effects on CNV. Administration of EYE-502 could inhibit VEGF-induced dysfunction of endothelial cells (ECs) and reduce platelet-derived growth factor (PDGF)-induced recruitment of pericytes to ECs in vitro. Administration of EYE-502 could reduce the area of choroidal sprouting and laser-induced CNV, exhibiting similar anti-angiogenic effects as aflibercept. Moreover, administration of EYE-502 could reduce pericyte coverage in the sprouting vessels and choroidal neovascularization. Mechanistically, EYE-502 primarily bound to retinoic acid receptors (RARs) and exerted the anti-angiogenic effects by targeting ECs and pericytes via affecting the activation of Wnt/β-catenin and PDGF/PDGFR/PI3K/Akt signaling. Taken together, this study reports a novel retinoic acid drug, EYE-502, which can exert the anti-angiogenic effects by simultaneous targeting of ECs and pericytes.
Stereotactic body radiation therapy for stage I medically operable non-small cell lung cancer
Authors: Kocak Uzel Esengul , Bagci Kilic Melisa , Morcali Hasan , Uzel Omer 
Published: June 2023

AbstractStereotactic ablative body radiation therapy (SBRT) has emerged as the standard treatment for inoperable patients with stage I non-small cell lung cancer (NSCLC). In the current study, we retrospectively analyzed a medically operable patient cohort with stage I NSCLC who refused surgery and subsequently underwent SBRT. Overall survival (OS) and progression-free survival (PFS) were calculated. Between April 2014 and July 2020, 55 patients were enrolled to the study. Forty (72.7%) patients were male, with a mean age of 69.85 ± 4.65 years (range 59–78 years). ECOG performance status were 0 and 1, except for one case. At the time of analysis, 8 deaths were observed. Of these, 25% (n = 2) died due to cardiac events, 12.5% (n = 1) due to pulmonary causes, 12.5% (n = 1) due to lung cancer-related causes, and the cause of death was unknown for 50% (n = 4). The pulmonary causes and cardiac events were not associated with radiation-induced toxicity. The median survival time was 34 months, with a range of 12 to 44 months. 2-year OS and PFS were 97% and 98%, 3-year OS and PFS were 82% and 77%, respectively. Treatment with SBRT was well tolerated and no grade 3 and 4 treatment-related adverse events were observed. SBRT seems to be a well- tolerated and effective alternative for patients with operable early-stage NSCLC.
A characterization of ASAS-SN core-collapse supernova environments with VLT+MUSE
Authors: Pessi T. , Prieto J. L. , Anderson J. P. , Galbany L. , Lyman J. D. , Kochanek C. , Dong S. , Forster F. , González-Díaz R. , Gonzalez-Gaitan S. , Gutiérrez C. P. , Holoien T. W.-S. , James P. A. , Jiménez-Palau C. , Johnston E. J. , Kuncarayakti H. , Rosales-Ortega F. , Sánchez S. F. , Schulze S. , Shappee B. 
Published: June 2023

Context. The analysis of core-collapse supernova (CCSN) environments can provide important information on the life cycle of massive stars and constrain the progenitor properties of these powerful explosions. The MUSE instrument at the Very Large Telescope (VLT) enables detailed local environment constraints of the progenitors of large samples of CCSNe. Using a homogeneous SN sample from the All-Sky Automated Survey for Supernovae (ASAS-SN) survey, an untargeted and spectroscopically complete transient survey, has enabled us to perform a minimally biased statistical analysis of CCSN environments.
Aims. We analyze 111 galaxies observed by MUSE that hosted 112 CCSNe – 78 II, nine IIn, seven IIb, four Ic, seven Ib, three Ibn, two Ic-BL, one ambiguous Ibc, and one superluminous SN – detected or discovered by the ASAS-SN survey between 2014 and 2018. The majority of the galaxies were observed by the All-weather MUse Supernova Integral field Nearby Galaxies (AMUSING) survey. Here we analyze the immediate environment around the SN locations and compare the properties between the different CCSN types and their light curves.
Methods. We used stellar population synthesis and spectral fitting techniques to derive physical parameters for all H II regions detected within each galaxy, including the star formation rate (SFR), Hα equivalent width (EW), oxygen abundance, and extinction.
Results. We found that stripped-envelope supernovae (SESNe) occur in environments with a higher median SFR, Hα EW, and oxygen abundances than SNe II and SNe IIn/Ibn. Most of the distributions have no statistically significant differences, except between oxygen abundance distributions of SESNe and SNe II, and between Hα EW distributions of SESNe and SNe II. The distributions of SNe II and IIn are very similar, indicating that these events explode in similar environments. For the SESNe, SNe Ic have higher median SFRs, Hα EWs, and oxygen abundances than SNe Ib. SNe IIb have environments with similar SFRs and Hα EWs to SNe Ib, and similar oxygen abundances to SNe Ic. We also show that the postmaximum decline rate, s, of SNe II correlates with the Hα EW, and that the luminosity and the Δm15 parameter of SESNe correlate with the oxygen abundance, Hα EW, and SFR at their environments. This suggests a connection between the explosion mechanisms of these events to their environment properties.
Shear, writhe, and filaments: Turbulence in the high-latitude molecular cloud MBM 40
Authors: Monaci Marco , Magnani Loris , Shore Steven N. , Olofsson Henrik , Joy Mackenzie R. 
Published: June 2023

Context.Given the structural and thermodynamical complexity of the interstellar medium (ISM), the variety of governing processes, such as stellar feedback, poses challenges to the investigation. High-latitude molecular clouds (HLMCs) with no evidence of internal star formation, as in the case of MBM 40, are excellent sites for studying the chemistry and dynamic evolution of the cold neutral ISM.Aims.We used this high-latitude cloud as an exemplar for the dynamical and chemical processes in the diffuse interstellar medium.Methods.We analyzed new and archival12CO,13CO, CH, HCO+, CS, H2CO, and HCN data from Five College Radio Observatory (FCRAO), Onsala Space Observatory (OSO), Arizona Radio Observatory (ARO), andW. Gordontelescope (Arecibo) combined with the Galactic Arecibo L-band Feed Array H I(GALFA-HI) H I21 cm data set, to study the chemistry, thermal state, and dynamics of MBM 40. A new dynamical analytical approach was adopted by considering each line profile as a line-of-sight probability distribution function (PDF) of the turbulence weighted by gas emissivity.Results.The atomic and molecular gas are smoothly distributed in space and velocity. No steep transition is seen between circumcloud atomic and cloud molecular gas in either radial velocity or structure. We propose a topology of the cloud based on molecular tracers, as a contorted filamentary structure that is shaped by a broad embedding shear flow in the neutral atomic gas. A comparative examination of different molecular tracers shows that13CO, H2CO, and CS only arise from denser molecular cores, whereas12CO, CH, and HCO+trace diffuse gas with a broader range of dynamics.
Management of Acutely Decompensated Pulmonary Hypertension
Authors: Savale Laurent , Kularatne Mithum , Roche Anne , Pichon Jérémie , Baron Audrey , Boucly Athenaïs , Sitbon Olivier , Humbert Marc 
Published: June 2023

AbstractPulmonary arterial hypertension is a severe life-threatening condition associated with increased pulmonary vascular resistance and resulting right heart dysfunction. Admission to intensive care unit with acutely decompensated right heart failure is a significant negative prognostic event with a high risk of multisystem organ dysfunction and death. Presentations are heterogenous and may combine signs of both diastolic and systolic dysfunction complicating management. Renal dysfunction is often present, but other organ systems can be involved resulting in findings such as acute hepatic dysfunction or bowel wall congestion and ischemia. The goals of therapy are to rapidly reverse ventriculo-arterial decoupling and reduce right ventricular afterload to prevent progression to refractory or irreversible right heart failure. Triggering events must be investigated for and addressed urgently if identified. Volume status management is critical and both noninvasive and invasive testing can aid in prognostication and guide management, including the use of inotropes and vasopressors. In cases of refractory right heart dysfunction, consideration of urgent lung transplantation and mechanical circulatory support is necessary. These patients should be managed at expert centers in an intensive care setting with a multidisciplinary team of practitioners experienced in the management of right heart dysfunction given the high short- and long-term mortality resulting from acute decompensated right heart failure.
Seeing and knowing
Authors: Bergqvist Henrik 
Published: June 2023

AbstractThe paper provides evidence against the claim that perceptual access is commonly encoded in direct evidentials. While visual, auditory, tactile and olfactory perception are conveyed by direct evidentials in contexts where such interpretations are appropriate, in others it is the speaker’s involvement, affectedness and established beliefs which are conveyed. These may be exclusive to the speaker or shared by the addressee. Instead of information source, it is argued that some direct evidentials encode the speaker’s epistemic authority regarding an event based on their primary relation to the event. Epistemic authority concerns the speaker’s rights over knowledge and is therefore a relational concept that captures some of the dynamics between speech act participants in terms of knowledge representation and attribution. Support for this argument comes from the diachronic development of direct evidentials, the effects of co-distribution between direct evidentials and person marking (egophoricity), and patterns of use. Data comes from the literature on evidentiality and frequently cited languages from Tucanoan and Quechuan languages that feature well-described, rich evidential systems.
Machine learning to predict environmental dose rates from a radionuclide therapy service — a proof of concept study
Authors: Meades Richard , Page Joanne , Ross James C , McCool Daniel 
Published: June 2023

Abstract
The Ionising Radiation Regulations 2017 requires prior risk assessment calculations and regular environmental monitoring of radiation doses. However, the accuracy of prior risk assessments is limited by assumptions and monitoring only provides retrospective evaluation. This is particularly challenging in nuclear medicine for areas surrounding radionuclide therapy patient bathroom wastewater pipework. Machine learning (ML) is a technique that could be applied to patient booking records to predict environmental radiation dose rates in these areas to aid prospective risk assessment calculations, which this proof-of-concept work investigates. 540 days of a dosimeters historical daily average dose rate measurements and the corresponding period of department therapy booking records were used to train six different ML models. Predicted versus measured daily average dose rates for the following 60 days were analysed to assess and compare model performance. A wide range in prediction errors was observed across models. The gradient boosting regressor produced the best accuracy (root mean squared error = 1.10 µSv.hr−1, mean absolute error = 0.87 µSv.hr−1, mean absolute percentage error = 35% and maximum error = 3.26 µSv.hr−1) and goodness of fit (R
2 = 0.411). Methods to improve model performance and other scenarios where this approach could prove more accurate were identified. This work demonstrates that ML can predict temporal fluctuations in environmental radiation dose rates in the areas surrounding radionuclide therapy wastewater pipework and indicates that it has the potential to play a role in improving legislative compliance, the accuracy of radiation safety and use of staff time and resources.
Narrow-band notch filter and refractive index sensor based on rectangular-semi-annular cavity coupled with MIM waveguide structure
Authors: Zhang Shu , Qi Yunping , Shi Qiang , Su Mingrui , Zhao Shiyu , Wang Xiangxian 
Published: June 2023

Abstract
In this work, a symmetric structure based on a metal-insulator-metal (MIM) waveguide is proposed for narrow-band notch filters and refractive index sensors. The structure comprises a symmetrically intersecting rectangular-semi-annular cavity and a long straight waveguide. The transmission spectrum and magnetic field distribution of the notch filter are studied and analyzed by the finite element method (FEM) with scattering boundary conditions (SBC). Our analysis reveals that the band-stop filter exhibits a minimum transmittance of 0.35%, a bandwidth of 34 nm, and a quality factor (Q) of 35.16. These characteristics include low stop-band transmittance, a narrow bandwidth, and a high Q value. Furthermore, our structure allows for independent adjustment of the narrow band filtering range by varying geometric parameters such as H, d, R1, and d. Additionly, we conduct theoretical analysis to investigate the sensing properties of the structure. The refractive index sensitivity of the structure reaches a high value of 1222 nm RIU−1, accompanied by a figure of merit(FOM*) of up to 175.9. These results demonstrate the structure’s excellent filtering properties and high-sensitivity sensing characteristics.Consequently, it holds significant potential for application in high-density integrated circuits and nano-optics.
Primordial black hole dark matter from catastrogenesis with unstable pseudo-Goldstone bosons
Authors: Gelmini Graciela B. , Hyman Jonah , Simpson Anna , Vitagliano Edoardo 
Published: June 2023

Abstract
We propose a new scenario for the formation of asteroid-mass primordial black holes (PBHs). Our mechanism is based on the annihilation of the string-wall network associated with the
breaking of a U(1) global symmetry into a discrete ZN
symmetry. If the potential has
multiple local minima (N > 1) the network is stable, and the annihilation is guaranteed by a bias
among the different vacua. The collapse of the string-wall network is accompanied by
catastrogenesis, a large production of pseudo-Goldstone bosons (pGBs) — e.g. axions,
ALPs, or majorons — gravitational waves, and PBHs. If pGBs rapidly decay into products that
thermalize, as predicted e.g. in the high-quality QCD axion and heavy majoron models, they do not
contribute to the dark matter population, but we show that PBHs can constitute 100% of the dark
matter. The gravitational wave background produced by catastrogenesis with heavy unstable axions,
ALPs, or majorons could be visible in future interferometers.
A fairy tale of winter - a theory about dark energy, dark matter, and inflation
Authors: Li Miao 
Published: June 2023

Abstract
This fairy tale begins with the journey of the famous Zhuang Zhou dreaming of a butterfly: I often do not know whether I am living in a dream, dreaming of a butterfly, or is a butterfly dreaming of me? Furthermore, there is the saying that those who believe it will see it, while for those who see it, it is then too late to believe it. The first thing I believe in is the holographic principle, and the holographic dark energy brought about by the holographic principle. Not until last year, I began to believe that there must be a new energy scale in between the Planck scale and the standard model scale. I also believe that this new scale is related to the minimal axion model. The results of the journey described in this paper are the following: 1. There is a new energy scale, which we will call the intermediate energy scale, and the best choice is

10

12

GeV. 2. The minimal axion exists, and under the new scale, there is no new physics. The axion plays both the roles of inflation and dark matter. New physics between the new scale and the Planck scale may exist because in this energy range, quantum gravity becomes important. 3. The dark energy is holographic dark energy. Then all of the observable effects of all three predictions about dark energy, dark matter, and cosmic inflation are to be observed.