bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regional Constellation Reconfiguration Problem: Integer Linear Programming Formulation and Lagrangian Heuristic Method
Authors: Lee Hang Woon , Ho Koki 
Published: July 2023

A group of satellites, with either homogeneous or heterogeneous orbital characteristics and/or hardware specifications, can undertake a reconfiguration process due to variations in operations pertaining to Earth observation missions. This paper investigates the problem of optimizing a satellite constellation reconfiguration process against two competing mission objectives: 1) the maximization of the total coverage reward, and 2) the minimization of the total cost of the transfer. The decision variables for the reconfiguration process include the design of the new configuration and the assignment of satellites from one configuration to another. We present a novel biobjective integer linear programming formulation that combines constellation design and transfer problems. The formulation lends itself to the use of generic mixed-integer linear programming (MILP) methods such as the branch-and-bound algorithm for the computation of provably optimal solutions; however, these approaches become computationally prohibitive even for moderately sized instances. In response to this challenge, this paper proposes a Lagrangian relaxation-based heuristic method that leverages the assignment problem structure embedded in the problem. The results from the computational experiments attest to the near-optimality of the Lagrangian heuristic solutions and a significant improvement in the computational runtime as compared to a commercial MILP solver.
Predicting the Solubility of Gases, Vapors, and Supercritical Fluids in Amorphous Polymers from Electron Density using Convolutional Neural Networks
Authors: Gromov Oleg 
Published: July 2023

A twin convolutional neural network is proposed to predict the pressure and temperature-dependent sorption of gases, vapors, and supercritical fluids in amorphous polymers based solely on spatial electron density distribution. Quantum chemical data as 3D tensors (3D images) is derived from DFT calculations. A dataset of almost 15000 experimentally measured uptakes (0.01-50 wt%) of 79 gases in 102 different polymers under pressures from 1E-3 – 7E+2 bar range and temperatures from 233-508 K range is collected from over 250 literature sources. The dataset includes measurements on almost 500 solvent-polymer systems spanning from typical low-pressure sorption in membrane glassy polymers to high-pressure solubility of supercritical fluids in molten polymers. Irreducible mean absolute percentage error (MAPE) is approximately estimated to be ~20%. The sources of inherent data variability are briefly discussed. In 150 epochs, the model achieved 31% MAPE on a test set of 1600 experimental measurements concerning 22 polymers previously unseen by the model.
IDENTIFICATION OF SUBSURFACE STRUCTURES IN SOUTH BENGKULU MANNA CITY BASED ON THE MASW METHOD
Authors: Saragih Ronni Samuel , Refrizon Refrizon , Hadi Arif Ismul 
Published: July 2023

South Bengkulu is one of the regencies in Bengkulu Province which is in an area of active tectonic plate activity, namely the India-Australia and Eurasian plates so it is prone to earthquakes. The City of Manna continues to carry out developments so that it requires various information for urban and regional planning, especially information on subsurface rock structures. This study aims to determine the structure of rock layers based on shear wave velocity (Vs), Poisson ratio, shear modulus and Young's modulus in Manna City. This research was conducted using the Multichannel Analysis of Surface Wave (MASW) method at 12 measurement stations. The tool used is the PASI 16S24-P seismograph. Data processing to produce a 1D model is WinMASW 5.0 Professional Software and to display 3-D data Voxler software is used based on the value of Vs. Then do the calculation to get the value of Vs30. From the results of the Vs30 value in the study area, it shows that the Manna City area consists of 4 rock types including soft soil (SE), stiff soil (SD), very dense soil and soft rock (SC) and rock (SB) rock types. The highest layering value of shear wave velocity (Vs) is at the fourth point with a value of Vs 386-1263 m/s, Poisson ratio 0.40-0.35, shear modulus 298-3652 MPa and Young's modulus 804-9430 MPa at a depth of 4.4 -30 meters. While the smallest value is at the sixth location point with a value of Vs 180-474 m/s, Poisson ratio 0.40-0.30 shear modulus 60-461 MPa, and Young's modulus 168-1.243 MPa at a depth of 2.6-30 meters.
Sudden Cardiac Death in a Neonate Due to Bilateral Absence of Coronary Artery Ostium
Authors: Nicole A Bailey , Khalifah A Aldawsari , Carlo M Zeidenweber , Danyal M Khan* 
Published: July 2023

Introduction: Congenital heart disease is a leading cause of neonatal mortality linked to birth defects. Despite the widespread availability of prenatal screenings, detection rates remain low. Accurate early detection of these lesions is pivotal to reducing neonatal morbidity and mortality. Methods: In this case, we present a neonate who experienced sudden cardiac death due to a rare, undiagnosed congenital cardiac anomaly - the bilateral absence of coronary artery ostium. Discussion: This case highlights the importance of prenatal detection of congenital cardiac anomalies. While fetal echocardiography is frequently utilized, it only identifies CHD in 36-50% of cases. This is attributed to inadequate imaging procedures, varied operator skills, and regional discrepancies. Early detection of severe CHD is essential for specialized treatment, thereby mitigating neonatal health risks and improving survival rates. Conclusion: Prenatal detection of CHD, especially coronary anomalies, continues to pose significant challenges. There is a pressing need to establish and enforce standardized protocols for fetal echocardiography aimed at these anomalies. To enhance care and improve outcomes, a joint effort between academic institutions and community centers is encouraged. Learning Objectives: •	Congenital coronary artery anomalies are a significant cause of sudden cardiac death in children. •	The absence of a coronary artery ostium is known to be associated with other congenital heart diseases, particularly pulmonary atresia with an intact ventricular septum. However, isolated coronary disease has also been reported in this case. •	Prenatal echocardiography is a valuable tool for diagnosing congenital heart disease. However, certain limitations may be encountered when diagnosing coronary artery anomalies.
Экономика Северо-Запада России: в поисках перспективной специализации
Authors: Лукин Е.В. 
Published: July 2023

В статье оцениваются перспективы структурной трансформации экономики регионов Северо-Западного федерального округа и формирования ее новой специализации в современных геополитических условиях. Проведен анализ существующей экономической специализации, охарактеризовано усредненное положение регионов в цепочках создания добавленной стоимости. Дано авторское видение дрейфа экономики Северо-Запада России в сторону усложнения и сопровождающего этот процесс изменения способности к генерации доходов. Оцениваются перспективы репозиционирования регионов СЗФО в цепочках создания добавленной стоимости в условиях резкого обострения санкционного давления.
Messiha and Stokes (2023). A Qualitative Study on the Contemporary Perspectives and Experiences of Co-residence during Covid-19 among ‘Boomeranging’ Young Adults and their Mothers in England. (Preprint)
Authors: Messiha Katrina , Stokes Gillian 
Published: July 2023

<p><strong>Abstract:</strong></p>
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<p>The ‘Boomerang Effect’ (BE) is a contemporary phenomenon in England and wider Europe, referencing young adults who move out of their parents' home to live independently but eventually return to live with their parents again. Despite concerns about residential independence and the intensification of BE due to the Covid-19 pandemic, there is limited qualitative data investigating it. This qualitative study utilises diary methods to elicit the perspectives and experiences from six mother-young adult child dyads in England for 21 days to enable holistic and dynamic insights on the day-to-day exposures to the BE phenomenon. Findings resulted in several salient themes: (1) prime concerns shaping living arrangements, (2) framing of [participant] role, (3) conceptualisation of [participant] identity, (4) nature of family relations, (5) depiction of independence, and (6) perceived situational input of Government. This work underscores the interdependent and complex relationship between structure and agency manifest in the BE context.</p>
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<p><em>This preprint contributes valuable knowledge to the existing literature on the Boomerang Effect and offers nuanced insights into the experiences of both young adults and their mothers as they navigate the challenges and opportunities presented by this contemporary trend during the Covid-19 pandemic. The implications of these findings may inform policies and support systems to better address the needs of young adults and families in the changing landscape of living arrangements. </em></p>
Перспективи газоносності гравігенних структур зони Красноріцького скиду Дніпровсько-Донецької западини України
Authors: Лазарук Я. Г. 
Published: July 2023

В осадових товщах багатьох нафтогазоносних басейнів світу встановлено гравігенні диз’юнктивні дислокації і пов’язані з ними плікативні структури. З такими структурами пов’язані численні родовища нафти і газу. Антиклінальні підняття осадового чохла, які простягаються вздовж зони Красноріцького скиду на південному сході Дніпровсько-Донецької западини, є типовими гравігенними утвореннями. З ними пов’язані близько півтора десятка газоконденсатних родовищ. Однак, у північно-західній частині низки продуктивних структур між Євгеніївським та Борівським родовищами на ділянці довжиною майже 40 км не відкрито жодного родовища вуглеводнів. За результатами вивчення гравігенних тектонічних дислокацій зони Красноріцького скиду встановлено, що склепіння прирозломних антикліналей зміщуються в плані слідом за зміщенням самих порушень. Таке зміщення склепінь у продуктивних відкладах родовищ може становити 0,5 км і більше. Неврахування зміщення структурних планів з глибиною може бути причиною невдач пошукового буріння в зонах гравігенних дислокацій. Тому в подальшому рекомендоване буріння похило спрямованих свердловин з метою розкриття продуктивних пластів в апікальних частинах піднять. На ділянці Муратівського скиду за даними сейсморозвідки встановлено три підняття. Показано невідповідність форми піднять і форми порушень з позицій гравігенного тектогенезу. Дана рекомендація для уточнення структурних побудов. За результатами зіставлення геологічних матеріалів і космічних фотографій простежений зв’язок долини ріки Сіверський Донець з Муратівським скидом. Висловлено припущення, що гравігеннідугоподібні порушення, з яких складається цей скид, відображаються в будові річкової долини дугоподібними вигинами древніх русел. За цією ознакою нами виділено ще три прогнозні складки довжиною від 2,0 до 3,5 км. Отримані результати з прогнозування нових гравігенних структур запропоновано використати для планування сейсморозвідувальних робіт на північно-західному продовженні Муратівського скиду.
KAJIAN DESAIN STREETSCAPE KORIDOR SEBAGAI UPAYA MENDUKUNG GREEN SUSTAINABLE ARCHITECTURE STUDI KASUS: JALAN TUNJUNGAN, KOTA SURABAYA
Authors: Prabarini Hanifah Fairuza , Purwanto Edi 
Published: July 2023

Abstract: Planning and development of streetscape architectural designs have become a necessity to implement green sustainable or environmentally friendly sustainable development. The City of Surabaya has many iconic areas, one of which is the streetscape of the Tunjungan Street. The results of the study show that the development is still paying attention to the beauty and aesthetics value without reducing the safety and comfort value for street users as a priority. There are several facilities that support street users such as the availability of trash cans, green open spaces, sidewalks, seats and suspension bridges, which also support bicycle users with parking facilities and special lanes for cyclists. Both day and night, the area provides a sense of comfort and safety to visitors with the availability of street lights that illuminate along the street. Several other facilities such as street signs and information boards also help in the effort to implement the green sustainable architecture. Based on these aspects and all the efforts that have been and are being carried out, the Surabaya City government as the person in charge of development, clearly indicates that it has made efforts to support Green Sustainable Architecture in the streetscape of the Tunjungan Street corridor.Abstrak: Perencanaan dan pembangunan desain arsitektur streetscape sudah menjadi keharusan untuk menerapkan green sustainable atau pembangunan berkelanjutan yang ramah lingkungan. Kota Surabaya memiliki banyak kawasan ikonik, salah satunya streetscape koridor Jalan Tunjungan. Hasil kajian terhadap desain streetscape koridor Jalan Tunjungan menunjukkan pembangunan kawasan jalan ini tetap memperhatikan nilai keindahan dan keestetikaannya tanpa mengurangi nilai keamanan serta kenyamanan bagi pengguna jalan sebagai prioritas. Terdapat beberapa fasilitas dan saranan yang menunjang bagi pengguna jalan seperti ketersediaan tempat sampah, ruang terbuka hijau, trotoar, tempat duduk dan jembatan gantung, yang juga menunjang bagi pengguna sepeda dengan adanya fasilitas tempat parkir dan jalur khusus pesepeda. Baik siang maupun malam hari, kawasan Jalan Tunjungan memberikan rasa kenyamanan serta keamanan bagi pengunjungnya dengan tersedianya lampu jalan yang menerangi sepanjang jalan. Beberapa fasilitas lain seperti rambu jalan dan papan informasi turut membantu dalam upaya implementasi green sustainable architektur. Berdasarkan aspek-aspek tersebut serta segala upaya yang sudah dan sedang dijalankan, pemerintah Kota Surabaya sebagai penanggung jawab pembangunan dan pengembangan, jelas mengindikasikan bahwa telah mengupayakan untuk mendukung Green Sustainable Architecture pada streetscape koridor Jalan Tunjungan.
Struktur komunitas Tumbuhan Bawah di Zona Pemanfaatan Blok Ireng-Ireng Taman Nasional Bromo Tengger Semeru (TNBTS)
Authors: Kurnia Anisa , Asmuni Hasyim Muhammad , Nugra Prasetya Koestriadi 
Published: July 2023

Indonesia is a country that has a very large tropical rain forest. The forest is a unified biological system as part of the earth there is an ordinary organic wealth covered with trees which in cooperation in their nature and current state cannot be separated. Groundcover is a basic vegetation component under forest stands other than tree rejuvenation, which consists of grasses, herbs and shrubs. Bromo Tengger Semeru National Park (TNBTS) is a conservation area with abundant biodiversity, both in terms of flora and fauna. The purpose of this study was to determine the genus of the undergrowth and dominancefound in the Ireng-Ireng Block Utilization Zone, Bromo Tengger Semeru National Park. The research method uses line and transect plots with 4 transects 20 m long, each with 5 plots measuring 1 x 1 m with a distance between plots of 3 m. Result research Found 13 genera as follows Davallia, Strychnos, Homalomena, Nheprolepis, Pheghopteris, Pteris, Ageratina, Sceleria, Molineria, Didymochlaena, Adiantum, Begonia, and Ruellia. The understorey plants that had the highest cover were from the Strychnos genus group with an important value index of 26.87 .

Keywords: structure, komposition, Groundcover, ireng ireng block utilization zone Bromo Tengger Semeru National Park.
Recombinant human TIM-3 ectodomain expressed in bacteria and recovered from inclusion bodies as a stable and active molecule
Authors: Lima G. C. , Chura-Chambi R. M. , Morganti L. , Silva V. J. , Cabral-Piccin M. P. , Rocha V. , Medina T. S. , Ramos R. N. , Luz D. 
Published: July 2023

Introduction: Microbial systems, such as Escherichia coli, as host recombinant expression is the most versatile and the cheapest system for protein production, however, several obstacles still remain, such as recovery of soluble and functional proteins from inclusion bodies, elimination of lipopolysaccharides (LPS) contamination, incomplete synthesis, degradation by proteases, and the lack of post-translational modifications, which becomes even more complex when comes to membrane proteins, because they are difficult not only to produce but also to keep in solution in its active state. T-cell Immunoglobulin and Mucin domain 3 (TIM-3) is a type I transmembrane protein that is predominantly expressed on the surface of T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages, playing a role as a negative immune checkpoint receptor. TIM-3 comprises a single ectodomain for interaction with immune system soluble and cellular components, a transmembrane domain, and a cytoplasmic tail, responsible for the binding of signaling and scaffolding molecules. TIM-3 pathway holds potential as a therapeutic target for immunotherapy against tumors, autoimmunity, chronic virus infections, and various malignancies, however, many aspects of the biology of this receptor are still incompletely understood, especially regarding its ligands.Methods: Here we overcome, for the first time, the challenge of the production of active immune checkpoint protein recovered from bacterial cytoplasmic inclusion bodies, being able to obtain an active, and non-glycosylated TIM-3 ectodomain (TIM-3-ECD), which can be used as a tool to better understand the interactions and roles of this immune checkpoint. The TIM-3 refolding was obtained by the association of high pressure and alkaline pH.Results: The purified TIM-3-ECD showed the correct secondary structure and was recognized from anti-TIM-3 structural-dependent antibodies likewise commercial TIM-3-ECD was produced by a mammal cells system. Furthermore, immunofluorescence showed the ability of TIM-3-ECD to bind to the surface of lung cancer A549 cells and to provide an additional boost for the expression of the lymphocyte activation marker CD69 in anti-CD3/CD28 activated human PBMC.Discussion: Taken together these results validated a methodology able to obtain active checkpoint proteins from bacterial inclusion bodies, which will be helpful to further investigate the interactions of this and others not yet explored immune checkpoints.
Predictive value of blood urea nitrogen in heart failure: a systematic review and meta-analysis
Authors: Duan Siyu , Li Yuqi , Yang Ping 
Published: July 2023

BackgroundThe mortality rate of patients with heart failure (HF) remains high, and when heart failure occurs, blood urea nitrogen (BUN) is involved in the perfusion of renal blood flow. Some studies have shown an association between heart failure prognosis and blood urea nitrogen, but the results of some other studies were inconsistent. Therefore, we conducted a comprehensive meta-analysis to investigate the value of BUN on the prognosis of patients with heart failure.MethodsA computerized systematic search of all English literature was performed in four databases, PubMed, Cochrane, Embase and Web of Science, from their inception to May 2022. The data of BUN were classified into continuous and categorical variables after passing the inclusion and exclusion criteria. The BUN data of both types were extracted separately into stata15.0 for statistical analysis.ResultsA total of 19 cohort studies involving 56,003 patients were included. When BUN was used as a categorical variable, the risk of death in heart failure was 2.29 times higher for high levels of BUN than for low levels of BUN (RR = 2.29, 95% CI:1.42–3.70, P &lt; 0.001). The results showed statistical significance in multifactorial and univariate groups, the prospective cohort, and European and Asian groups. When BUN was used as a continuous variable, the risk of death in heart failure was 1.02 times higher for each unit increase in BUN (RR = 1.02, 95% CI:1.01–1.03, p &lt; 0.001). Subgroup analysis showed statistical significance in retrospective cohort, American and Asian.ConclusionHigh BUN is an independent predictor of all-cause mortality in heart failure. Lower BUN was associated with better prognosis in patients with heart failure.
Faults and stratigraphic boundaries control evolution of the huge debris flows along the Jinjiang River, China
Authors: Liu Zhuoya , Wen Yi , Mao Xianyin , Lv Qianyong , Zeng Guisen 
Published: July 2023

This paper investigates the controlling factors of the evolution of debris flows along the Jinjiang River, which is located in an active orogen. The debris flows along the Jinjiang River are threatening nomads and pastures, as well as the power station on the river and its workers. Remote sensing images, geological maps, and field investigations were conducted to determine the distribution of the lithologies, faults, and debris flows. A total of 82.2 km of riverbank and 108 debris flows, including 22 huge flows, were investigated. The results indicate that the distribution of the huge debris flows is primarily controlled by either faults or boundaries between the sedimentary rocks and basalt. Both the faults and the stratigraphic boundaries play crucial roles in the evolution of the huge debris flows along the river. The fractured zone of faults and stratigraphic boundaries provides loose resource materials for the debris flows and is a weak strip prone to incision to become a debris flow valley. However, the lithology has relatively less impact on the evolution of the huge debris flows.