bluuebunny/crossref_metadata_2025_split huggingface dataset:
Redefinition of the Petersburg batholith and implications for crustal inheritance in the Dinwiddie terrane, Virginia, USA
Authors: Carter Mark W. , McAleer Ryan J. , Holm-Denoma Christopher S. , Occhi Marcie E. , Owens Brent E. , Vazquez Jorge A. 
Published: April 2023

Abstract
Field relations as well as geochemical and petrologic studies of metaigneous rocks assigned to the Pennsylvanian–Permian Petersburg batholith identify at least two distinct rock types: foliated metagranitoid gneiss and massive to porphyritic granite. Foliated metagranitoid gneiss of mostly granodioritic composition is geochemically distinct from associated massive and porphyritic granitic rocks. These gneissic rocks yield radiometric ages from ca. 425 Ma to ca. 403 Ma and document that many of the rocks assigned to the late Paleozoic Petersburg batholith are 100 m.y. older than the youngest portions of the composite batholith and are part of an earlier infrastructural terrane. Two samples of massive equigranular granite southwest of Petersburg, Virginia, yield ages of ca. 321 Ma and ca. 317 Ma, which are 15–20 m.y. older than ca. 300 Ma ages for porphyritic granite, massive granite, and monzodiorite near Richmond, Virginia. Geologic mapping shows that the Early Pennsylvanian granite southwest of Petersburg is separated from Late Pennsylvanian to early Permian granite near Richmond by a map-scale septum of Silurian–Devonian foliated metagranitoid gneiss, referred to herein as the informal Pocoshock Creek gneiss. Laser ablation–inductively coupled plasma–mass spectrometry data from one sample of a quartz-muscovite felsic schist xenolith show a peak age mode of ca. 529 Ma that we interpret to be the maximum depositional age. Inherited zircons from foliated metagranitoid gneiss and massive equigranular granite range from ca. 631 Ma to ca. 376 Ma, but many are Cambrian. Neoproterozoic–Cambrian quartz-muscovite felsic schist and amphibolite, Silurian–Devonian Pocoshock Creek gneiss, and Pennsylvanian–Permian granite comprise a fault-bounded terrane referred to herein as the Dinwiddie terrane. Ages of inherited cores in zircon from igneous rocks and limited detrital zircon geochronology suggest the terrane is of peri-Gondwanan affinity. U/Pb ages of healed fractures in zircon grains from foliated metagranitoid gneiss indicate low-grade deformation of the gneiss at ca. 378–376 Ma, while ca. 320–280 Ma rims on many grains record intrusion of late Paleozoic granite. The temperature-time-deformation history of the Dinwiddie terrane is distinct from the adjacent Goochland and Roanoke Rapids terranes. Orogen-scale dextral transpression likely translated the Dinwiddie terrane southward during the Alleghanian orogeny, at which time they were intruded by Pennsylvanian to Permian granite.
Stability of a Magnetically Actuated Satellite towards the Sun on a Sun-Synchronous Orbit
Authors: Roldugin D. S. 
Published: April 2023

Abstract
Magnetically actuated satellite moving on a Sun-synchronous orbit is considered. The satellite maintains one axis attitude towards the Sun while rotating around this direction. Stabilization algorithm utilizes information about the required direction and rotation rate. Evolutionary equations are used to find equilibrium positions and analyze their stability. Conditions on the satellite inertia moments and control parameters are established for different equilibria, including the required motion. Numerical simulation with different disturbing sources is performed to verify stable equilibria existence.
Beverage consumption and mortality among adults with type 2 diabetes: prospective cohort study
Authors: Ma Le , Hu Yang , Alperet Derrick J , Liu Gang , Malik Vasanti , Manson JoAnn E , Rimm Eric B , Hu Frank B , Sun Qi 
Published: April 2023

AbstractObjectiveTo investigate the intake of specific types of beverages in relation to mortality and cardiovascular disease (CVD) outcomes among adults with type 2 diabetes.DesignProspective cohort study.SettingHealth professionals in the United States.Participants15 486 men and women with a diagnosis of type 2 diabetes at baseline and during follow-up (Nurses’ Health Study: 1980-2018; and Health Professionals Follow-Up Study: 1986-2018). Beverage consumption was assessed using a validated food frequency questionnaire and updated every two to four years.Main outcome measuresThe main outcome was all cause mortality. Secondary outcomes were CVD incidence and mortality.ResultsDuring an average of 18.5 years of follow-up, 3447 (22.3%) participants with incident CVD and 7638 (49.3%) deaths were documented. After multivariable adjustment, when comparing the categories of lowest intake of beverages with the highest intake, the pooled hazard ratios for all cause mortality were 1.20 (95% confidence interval 1.04 to 1.37) for sugar sweetened beverages (SSBs), 0.96 (0.86 to 1.07) for artificially sweetened beverages (ASBs), 0.98 (0.90 to 1.06) for fruit juice, 0.74 (0.63 to 0.86) for coffee, 0.79 (0.71 to 0.89) for tea, 0.77 (0.70 to 0.85) for plain water, 0.88 (0.80 to 0.96) for low fat milk, and 1.20 (0.99 to 1.44) for full fat milk. Similar associations were observed between the individual beverages and CVD incidence and mortality. In particular, SSB intake was associated with a higher risk of incident CVD (hazard ratio 1.25, 95% confidence interval 1.03 to 1.51) and CVD mortality (1.29, 1.02 to 1.63), whereas significant inverse associations were observed between intake of coffee and low fat milk and CVD incidence. Additionally, compared with those who did not change their consumption of coffee in the period after a diabetes diagnosis, a lower all cause mortality was observed in those who increased their consumption of coffee. A similar pattern of association with all cause mortality was also observed for tea, and low fat milk. Replacing SSBs with ABSs was significantly associated with lower all cause mortality and CVD mortality, and replacing SSBs, ASBs, fruit juice, or full fat milk with coffee, tea, or plain water was consistently associated with lower all cause mortality.ConclusionsIndividual beverages showed divergent associations with all cause mortality and CVD outcomes among adults with type 2 diabetes. Higher intake of SSBs was associated with higher all cause mortality and CVD incidence and mortality, whereas intakes of coffee, tea, plain water, and low fat milk were inversely associated with all cause mortality. These findings emphasize the potential role of healthy choices of beverages in managing the risk of CVD and premature death overall in adults with type 2 diabetes.
Whole person assessment for family medicine: a systematic review
Authors: Thomas Hayley Robyn , Best Megan , Chua David , King David , Lynch Johanna 
Published: April 2023

ObjectivesTo identify and evaluate clinical approaches to whole person assessment (WPA) that are translatable to family medicine regarding feasibility, quality and alignment with theoretical models of whole person care (WPC).DesignSystematic literature review.Data sourcesMEDLINE, CINAHL, PsycINFO and ATLA Religion databases were searched through 9 March 2020, with additional handsearches.Eligibility criteriaEnglish language clinical assessments of multiple domains; which involve patient–clinician interaction and are translatable to general practice (GP); from the fields of medicine, allied health, nursing, mental health and pastoral care. Tools designed for single diseases or symptoms, for outcome rather than clinical assessment or with outdated classification systems were excluded.Data extraction and synthesisWe appraised the quality of included papers using Johanna Briggs’ Institute Checklists and Terwee’s criteria for validation studies. Clinical assessments’ alignment with theoretical WPC, feasibility for adaptation to GP and quality were examined. We analysed extracted data using framework synthesis.ResultsSearches retrieved 7535 non-duplicate items. Fifty-nine were included after screening, describing 42 WPA methods and representing multiple disciplines, purposes and formats. All included assessments aligned partially with models of WPC, but most did not adequately encompass all aspects of WPC. Robustness varied significantly and was often inadequately described. We judged none of the identified assessments to be ideal as a multipurpose WPA in GP. Some could be used for specific purposes, such as elicitation of patient perspectives or complexity assessment.ConclusionsWhile no WPAs were found that were sufficient for broad implementation in GP, some approaches may be suitable with adaptation and evaluation. Strengths of existing approaches could inform WPA development in future.PROSPERO registration numberCRD42020164417.
Well-being focused interventions for caregivers of children with developmental disabilities: a scoping review protocol
Authors: Abeasi Doreen Asantewa , Nkosi Nokuthula Gloria , Suglo Joseph Ngmenesegre 
Published: April 2023

IntroductionChildren with developmental disability (DD) may depend on their family caregivers to fulfil their complex health needs. Family caregivers are generally described as persons providing unpaid for services for the child with DD at home who need to be supported in a manner that supports and promotes his/her well-being. This review aims to identify and map the range of interventions available for caregivers of children between the ages of 5–16 with DD.Methods and analysisThe methodological framework for conducting scoping review as published by Arksey and O’Malley and the Joanna Briggs Institute’s guidelines will used in this study. Primary research articles will be obtained through a systematic search of CINAHL, Psych INFO, PubMed, ERIC and COCHRANE Library. Further grey literature will be obtained from Google Scholar search. Study selection process will be done by two independent researchers based on a predetermined inclusion criteria. Review findings comprising interventions, intervention components and outcomes will be presented using tables and narrative text.DiscussionThe proposed scoping review will give an extensive review of interventions aimed at improving the well-being of caregivers of children with DD. This scoping review would provide recommendations on interventions that have significantly improved the well-being caregivers of children with DD. Additionally, the review would guide future work on intervention development and primary research in this field.RegistrationThis scoping review protocol has been registered with the Open Science Framework (https://osf.io/tkbrh).
SARS-CoV-2 seroprevalence and living conditions in Bamako (Mali): a cross-sectional multistage household survey after the first epidemic wave, 2020
Authors: Cissoko Mady , Landier Jordi , Kouriba Bourema , Sangare Abdoul Karim , Katilé Abdoulaye , Djimde Abdoulaye A , Berthé Ibrahima , Traore Siriman , Thera Ismaila , Hadiata Maiga , Sogodogo Elisabeth , Coulibaly Karyn , Guindo Abdoulaye , Dembele Ousmane , Sanogo Souleymane , Doumbia Zoumana , Dara Charles , Altmann Mathias , Bonnet Emmanuel , Balique Hubert , Sagaon-Teyssier Luis , Vidal Laurent , Sagara Issaka , Bendiane Marc-Karim , Gaudart Jean 
Published: April 2023

ObjectivesIn low-income settings with limited access to diagnosis, COVID-19 information is scarce. In September 2020, after the first COVID-19 wave, Mali reported 3086 confirmed cases and 130 deaths. Most reports originated from Bamako, with 1532 cases and 81 deaths (2.42 million inhabitants). This observed prevalence of 0.06% appeared very low. Our objective was to estimate SARS-CoV-2 infection among inhabitants of Bamako, after the first epidemic wave. We assessed demographic, social and living conditions, health behaviours and knowledges associated with SARS-CoV-2 seropositivity.SettingsWe conducted a cross-sectional multistage household survey during September 2020, in three neighbourhoods of the commune VI (Bamako), where 30% of the cases were reported.ParticipantsWe recruited 1526 inhabitants in 3 areas, that is, 306 households, and 1327 serological results (≥1 years), 220 household questionnaires and collected answers for 962 participants (≥12 years).Primary and secondary outcome measuresWe measured serological status, detecting SARS-CoV-2 spike protein antibodies in blood sampled. We documented housing conditions and individual health behaviours through questionnaires among participants. We estimated the number of SARS-CoV-2 infections and deaths in the population of Bamako using the age and sex distributions.ResultsThe prevalence of SARS-CoV-2 seropositivity was 16.4% (95% CI 15.1% to 19.1%) after adjusting on the population structure. This suggested that ~400 000 cases and ~2000 deaths could have occurred of which only 0.4% of cases and 5% of deaths were officially reported. Questionnaires analyses suggested strong agreement with washing hands but lower acceptability of movement restrictions (lockdown/curfew), and mask wearing.ConclusionsThe first wave of SARS-CoV-2 spread broadly in Bamako. Expected fatalities remained limited largely due to the population age structure and the low prevalence of comorbidities. Improving diagnostic capacities to encourage testing and preventive behaviours, and avoiding the spread of false information remain key pillars, regardless of the developed or developing setting.EthicsThis study was registered in the registry of the ethics committee of the Faculty of Medicine and Odonto-Stomatology and the Faculty of Pharmacy, Bamako, Mali, under the number: 2020/162/CA/FMOS/FAPH.
Association between hysterectomy and hypertension among Indian middle-aged and older women: a cross-sectional study
Authors: Mustafa Akif 
Published: April 2023

ObjectiveTo examine the association between hysterectomy and hypertension among middle-aged and older women in India, as well as to determine if the association differs across different age groups.DesignA cross-sectional exploratory study.Setting and participantsNationally representative population-based data of the Longitudinal Ageing Study in India (2017–2018) were used in this study. The sample included 32 460 women aged 45 years and above.Outcome measuresSelf-reported hypertension was the outcome variable. The variable was a binary variable, with 1 representing hypertensive and 0 representing not hypertensive.MethodsEntropy balance method, along with logistic regression analysis, was used to meet the objectives.Results31.3% of the women without hysterectomy and 42.5% of the women with hysterectomy were hypertensive. A perfect covariate balance was achieved between the treatment and control groups using the entropy balance method. Women with hysterectomy had 36% (OR 1.36; 95% CI 1.26 to 1.48) higher odds of hypertension than women without hysterectomy. The OR was 1.23 (95% CI 1.03 to 1.47) for the age group 45–49, whereas, for the age group 80+, it was 1.87 (95% CI 1.18 to 2.97), showing that the magnitude of the association between hysterectomy and hypertension varied with age.ConclusionThe findings of this study suggest that hysterectomy and hypertension have a significant association in middle-aged as well as older women in India.
Anisotropic compact stellar solution in general relativity
Authors: Baskey Lipi , Ray Saibal , Das Shyam , Majumder Shreya , Das Ananya 
Published: April 2023

AbstractWe present herein a new class of singularity-free interior solutions to describe realistic anisotropic compact stellar objects with spherically symmetric matter distribution. A specific form of anisotropy is assumed to obtain the exact solution for the field equation. Smooth matching of interior solutions thus obtained with the Schwarzschild exterior metric over the bounding surface of a compact star, together with the condition that the radial pressure vanishes at the boundary, is used to obtain the mathematical form for the model parameters. The pulsar 4U1608-52 with its current estimated data (mass $$=1.57 ~M\odot $$

=
1.57

M
⊙

and radius $$=9.8 \pm 0.8$$

=
9.8
±
0.8

km; Özel et al. in ApJ 820:28, 2016) is used to study the model graphically.
Large scale analysis of gender bias and sexism in song lyrics
Authors: Betti Lorenzo , Abrate Carlo , Kaltenbrunner Andreas 
Published: April 2023

AbstractWe employ Natural Language Processing techniques to analyse 377,808 English song lyrics from the “Two Million Song Database” corpus, focusing on the expression of sexism across five decades (1960–2010) and the measurement of gender biases. Using a sexism classifier, we identify sexist lyrics at a larger scale than previous studies using small samples of manually annotated popular songs. Furthermore, we reveal gender biases by measuring associations in word embeddings learned on song lyrics. We find sexist content to increase across time, especially from male artists and for popular songs appearing in Billboard charts. Songs are also shown to contain different language biases depending on the gender of the performer, with male solo artist songs containing more and stronger biases. This is the first large scale analysis of this type, giving insights into language usage in such an influential part of popular culture.
Geometric Schrödinger microfluidic modeling for spherical ferromagnetic mKdV flux
Authors: Körpinar Talat , Körpinar Zeliha , Korkmaz Erdal 
Published: April 2023

In this paper, we present a different technique for investigating spherical [Formula: see text]-microfluidic optical mKdV electromotive [Formula: see text] forces in [Formula: see text] Then, we give some relations for ferromagnetic spherical [Formula: see text]-microfluidic optical mKdV magnetic [Formula: see text] flux density. Ferromagnetic spherical [Formula: see text]-microfluidic optical mKdV magnetic [Formula: see text] flux surface model. Finally, we obtain spherical [Formula: see text]-microfluidic optical mKdV magnetic [Formula: see text] flux density.
The Alpi Apuane and their surroundings: a tale of the origins of modern Italian geological maps and of a missed ‘early recognition’ of nappes in the Apennines
Authors: Molli Giancarlo 
Published: April 2023

Abstract
The northernmost coastal sector of the Italian peninsula from the La Spezia Gulf to Monte Pisano, including the Alpi Apuane mountain range, represents a special morpho-structural domain of the inner northwestern Apennines. Described by naturalists since the Roman age, its location on the land and sea track of the Italian Grand Tour makes it a special zone in the Italian peninsula that was visited by some of the most eminent European geologists of the nineteenth century, including Brongniart, Buckland, De la Beche, Hoffman, Escher von der Linth, Murchison and Lyell. The area has been also the homeland of naturalists and scientists who played a significant role during the nineteenth century in the advancement of geological studies in Italy. Thanks to Capellini's ‘Geological map of the La Spezia Gulf and surroundings’ (1863) and Zaccagna's ‘Geological maps of the Alpi Apuane’ (1879–97), the area became central in the history of the foundations of modern Italian geological maps. However, the opportunities provided by early mapping and palaeontological discoveries for developing tectonic concepts were squandered by Italian Apennines geologists, who remained stuck on explanations of autochthonism, thus missing an early recognition of nappe tectonics that was only accepted in the middle of the twentieth century.
Macroalgae Improve the Growth and Physiological Health of White Shrimp (Litopenaeus vannamei)
Authors: Zhang Zhuofan , Shi Xiaohui , Wu Zijie , Wu Wenbo , Zhao Qun , Li Erchao 
Published: April 2023

This study compared and evaluated the effects of nine native macroalgae species on the tropic coast of China on the growth and physiological health performance of white shrimp (Litopenaeus vannamei). Nine hundred juvenile shrimps weighing

1.6
±
0.02

g were fed with nine different types of macroalgae for 28 days. The experimental groups were as follows: Con (the diet without macroalgae), CRA (Caulerpa racemosa), CLA (Caulerpa lentillifera), CSS (Caulerpa sertularioides), CLM (Chaetomorpha linum), ULA (Ulva lactuca), GBE (Gracilaria bailiniae), ASA (Acanthophora spicifera), SVC (Sargassum ilicifolium var. conduplicatum), and BGE (Betaphycus gelatinae). Results showed that the growth performance of shrimps fed on the macroalgae meals was significantly higher than that of the control group (

P
<
0.05

). The immune defense capacity (total hemocyte count, phagocytosis respiratory bursts, prophenoloxidase system, hemagglutination activity, and antibacterial and bacteriolytic activities) and antioxidant capacity (total antioxidant capacity, superoxide dismutase, catalase, glutathione peroxidase, and malondialdehyde) of L. vannamei fed on macroalgae meals were significantly higher than those of the control group (

P
<
0.05

). Specifically, the shrimps in the ASA group had the significantly higher physiological health level than shrimps in the other macroalgae groups (

P
<
0.05

), and the expression of immune and antioxidation-related genes was also significantly higher in the ASA group (

P
<
0.05

). Principal component analysis (PCA) demonstrated that optimal growth and physiological health efficacy were observed in the ASA group. In summary, this study suggested dietary manipulation using macroalgae to improve the growth performance, immune performance, and antioxidant capacity of L. vannamei, with the optimal macroalgae for the diet being Acanthophora spicifera.
Collagen-Anchored Interleukin-2 and Interleukin-12 Safely Reprogram the Tumor Microenvironment in Canine Soft-Tissue Sarcomas
Authors: Stinson Jordan A. , Sheen Allison , Momin Noor , Hampel Jordan , Bernstein Rebecca , Kamerer Rebecca , Fadl-Alla Bahaa , Samuelson Jonathan , Fink Elizabeth , Fan Timothy M. , Wittrup K. Dane 
Published: April 2023

Abstract

Purpose:
Cytokine therapies such as IL2 and IL12 suffer from impractically small therapeutic windows driven by their on-target, off-tumor activity, limiting their clinical potential despite potent antitumor effects. We previously engineered cytokines that bind and anchor to tumor collagen following intratumoral injection, and sought to test their safety and biomarker activity in spontaneous canine soft-tissue sarcomas (STS).

Experimental Design:
Collagen-binding cytokines were canine-ized to minimize immunogenicity and were used in a rapid dose-escalation study in healthy beagles to identify a maximum tolerated dose. Ten client-owned pet dogs with STS were then enrolled into trial, receiving cytokines at different intervals prior to surgical tumor excision. Tumor tissue was analyzed through IHC and NanoString RNA profiling for dynamic changes within treated tumors. Archived, untreated STS samples were analyzed in parallel as controls.

Results:
Intratumorally administered collagen-binding IL2 and IL12 were well tolerated by STS-bearing dogs, with only Grade 1/2 adverse events observed (mild fever, thrombocytopenia, neutropenia). IHC revealed enhanced T-cell infiltrates, corroborated by an enhancement in gene expression associated with cytotoxic immune function. We found concordant increases in expression of counter-regulatory genes that we hypothesize would contribute to a transient antitumor effect, and confirmed in mouse models that combination therapy to inhibit this counter-regulation can improve responses to cytokine therapy.

Conclusions:
These results support the safety and activity of intratumorally delivered, collagen-anchoring cytokines for inflammatory polarization of the canine STS tumor microenvironment. We are further evaluating the efficacy of this approach in additional canine cancers, including oral malignant melanoma.