bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thyroid hormone rewires cortical circuits to coordinate body-wide metabolism and exploratory drive
Authors: Hochbaum Daniel R. , Dubinsky Alexandra C. , Farnsworth Hannah C. , Hulshof Lauren , Kleinberg Giona , Urke Amanda , Wang Wengang , Hakim Richard , Robertson Keira , Park Canaria , Solberg Alyssa , Yang Yechan , Baynard Caroline , Nadaf Naeem M. , Beron Celia C. , Girasole Allison E. , Chantranupong Lynne , Cortopassi Marissa , Prouty Shannon , Geistlinger Ludwig , Banks Alexander , Scanlan Thomas , Greenberg Michael E. , Boulting Gabriella L. , Macosko Evan Z. , Sabatini Bernardo L. 
Published: August 2023

AbstractAnimals adapt to varying environmental conditions by modifying the function of their internal organs, including the brain. To be adaptive, alterations in behavior must be coordinated with the functional state of organs throughout the body. Here we find that thyroid hormone— a prominent regulator of metabolism in many peripheral organs— activates cell-type specific transcriptional programs in anterior regions of cortex of adult mice via direct activation of thyroid hormone receptors. These programs are enriched for axon-guidance genes in glutamatergic projection neurons, synaptic regulators across both astrocytes and neurons, and pro-myelination factors in oligodendrocytes, suggesting widespread remodeling of cortical circuits. Indeed, whole-cell electrophysiology recordings revealed that thyroid hormone induces local transcriptional programs that rewire cortical neural circuits via pre-synaptic mechanisms, resulting in increased excitatory drive with a concomitant sensitization of recruited inhibition. We find that thyroid hormone bidirectionally regulates innate exploratory behaviors and that the transcriptionally mediated circuit changes in anterior cortex causally promote exploratory decision-making. Thus, thyroid hormone acts directly on adult cerebral cortex to coordinate exploratory behaviors with whole-body metabolic state.
Paths leading contractual disputes to litigation
Authors: Jagannathan Murali , Delhi Venkata Santosh Kumar 
Published: August 2023

PurposeJudiciary plays a pivotal role in the overall development of a nation's economy and its involvement assures process transparency and impartiality. However, litigation is often expensive, uncertain and prone to delays. Notwithstanding such inherent challenges associated with litigation, it is observed that parties in construction disputes do resort to litigation. This study attempts to understand the potential paths triggering litigation of contractual disputes in construction. While extant researchers have identified focus areas or factors influencing litigation, the underlying paths connecting these focus areas, leading parties to litigation, is explored in this study.Design/methodology/approachConsidering the framework of Rachlinski's “framing theory of litigation” and the mixed-methods approach (qualitative and quantitative approaches), this study proposes and validates a model that identifies the paths to litigation of contractual disputes in construction.FindingsThe results of in-depth interviews, followed by validation through structural equation modelling (SEM), reveal four critical paths, namely positional focus (PF) – contract and dispute characteristics (CDC) – decision to litigate (DTL), milieu influence (MI) – CDC – DTL, MI-PF-DTL and CDC-DTL.Practical implicationsThe identified paths highlight the areas policymakers can consider while developing policy interventions to mitigate litigation.Originality/valueResearchers have identified factors causing litigation in construction. However, attempts to examine the existence of multi-factor “paths” on the decision to litigate (DTL) have hitherto received a muted response, so this study focuses on identifying the project-level path(s) leading to the litigation of contractual disputes in construction.
The optimum use of high-strength steel in the construction of gas transmission pipeline
Authors: Guillal Abdelkader , Abdelbaki Noureddine 
Published: August 2023

PurposeThe aim of this study is to assess the opportunity for the development of hydrocarbon transportation using high-strength steel (HSS) in pipeline construction in terms of cost savings and reliability.Design/methodology/approachSeveral optimizations of pipeline design and operations were performed to estimate the total life-cycle cost variation associated with different grades of high-strength steel. The generalized reduced gradient (GRG) method was used in an Excel table to determine optimal total life cycle each pipeline. Variables used in this optimization with respect to each steel grade were as follows: pipeline external diameter, wall thickness, number of compression stations and installed power in each compression station. The reliability of a pipeline with optimal cost was assessed to highlight the impact of steel grade on pipeline reliability.FindingsThe study showed that the cost reduction is strongly dependent on the adopted gas pipeline configuration. The number of compression stations and external diameter are the main factors influencing the pipeline total life cycle cost, while the steel price seems to have a minor effect, the reduction of the gas pipeline total life cycle does not exceed 5% even with a 50% difference in pipe steel prices between X70 and X100 steels. On the other side, for the same external diameter, X100 steel presents better pipeline reliability against carbonic corrosion compared to X70 steel.Practical implicationsThe main contribution of this study is to provide a decision-support tool to help pipeline constructors enhance the profitability of natural gas transmission pipelines. The optimization method used is simple to use for design engineers during a feasibility study.Originality/valueThe present study presents one step to fill the gap concerning the question of balancing the trade-off between cost savings and structural reliability in high-strength steel pipelines during the early stages of feasibility studies. The optimal design and operations parameters ensuring cost savings on total life cycle costs are identified via an optimization method. The impact of selected optimal parameters on the long-term pipeline service life was estimated via a structural reliability analysis.
Technology and family business: from conceptualization to implementation in strategic planning – a perspective article
Authors: Gandrita Daniel Mandel 
Published: August 2023

PurposeThis article offers a perspective on the evolution of strategic planning and strategic planning's implementation, particularly within the context of family business. This paper is structured into three sections: Introduction, literature review (LR), conclusion and practical and theoretical implications. The LR critically examines traditional planning tools and highlights the need for adopting new digital concepts to enhance effectiveness and resource management in family business.Design/methodology/approachThe author employed a LR to synthesize all the information and to identify the authors/articles related to the object of study.FindingsThe use of technology to overcome strategic planning pitfalls and leverage emerging technologies while making data-driven decisions is a key factor for family businesses to stay ahead of the curve and achieve sustainable growth.Originality/valueThis study explores the historical development of strategic planning tools and discusses the transformative impact of technology on the traditional landscape, with a specific focus on strategic planning's reflection in family businesses.
Accounting infrastructure and promissory sustainable extractive industries: an actor-network theory analysis
Authors: Tran Hang , Nguyen Lan Anh , Lemma Tesfaye 
Published: August 2023

Purpose
This study aims to articulate the conceptual foundations of the role of accounting infrastructure (calculative practice and the communicative dimension of accounting) in extractive industries (EIs) towards a sustainable orientation from an actor-network theory (ANT) perspective.

Design/methodology/approach
This study is a literature-based analysis of the calculative property and communicative dimension of accounting in EIs, using the concepts of calculability, assemblage and other related concepts from ANT to identify potentialities and limits of the roles of accounting in this sector.

Findings
While accounting infrastructure can influence social and environmental outcomes, it has not, as yet, led to ecologically and socially sustainable practices in EIs. Calculative properties and the communicative dimension of accounting infrastructure have capabilities to foster the phenomenon of “sustainability” in EIs by valuing, disclosing (reporting) and governing EIs towards a sustainable orientation. Conceptualizing sustainable EIs as a promissory economy, accounting infrastructure serves as a tool not only to represent past performance but also to enact the future: it helps to shape a sustainable future for the industry by informing and triggering behavioural decisions of EIs firms towards sustainable practices.

Research limitations/implications
This conceptual paper is anticipated to stimulate future sustainability accounting research. The research agenda discussed in this paper can be used to enrich our understanding of the role of accounting in sustainability.

Originality/value
This paper charts a direction for future research by interpreting the role of sustainability accounting within networks of sociotechnical relations, using ANT concepts which attach importance to the dualism of nature and society. Conceptualizing sustainability accounting and reporting as an infrastructure, which draws more attention to the relationality characteristic of accounting, the study goes beyond the traditional interpretation of accounting as a mediation device and draws on a contemporary view of accounting by invoking the dynamic relation between accounting and society, in the context of EIs.
CSR as an impression-management strategy: the joint effect of disclosure tone management and earnings management
Authors: Hamza Sourour , Mezgani Naoel , Jarboui Anis 
Published: August 2023

Purpose
This study aims to investigate corporate social responsibility (CSR) as an impression management strategy. It focuses on CSR associated with, both, disclosure tone management (TM) and earnings management (EM) practices to influence stakeholders’ perceptions.

Design/methodology/approach
Based on a sample of French listed companies (SBF 120) over an eight-year period, this study empirically investigated a total of 616 firm-year observations. This study firstly investigates the impact of EM and disclosure TM practices on CSR. Then, this study examines their joint effect to explore to which extent CSR is abused for impression management inducement. To address potential endogeneity issue that may be caused by reverse causality between CSR and EM, this study used the two-stage least square.

Findings
Multivariate analyses indicate that CSR is positively and significantly influenced by EM, but negatively correlated to disclosure TM. However, results highlight the absence of a significant joint effect of both discretionary practices

Research limitations/implications
Because this study deals only with French companies, results are applicable only to large French firms and should be interpreted with caution. Therefore, future research may need to examine another context.

Practical implications
As CSR may be used for impression management incentives, all actors interested in socially responsible issues have to bring an initiative to prevent the deviation of CSR from moral and ethical standards.

Social implications
This study sheds light on the impression management strategies used in CSR reporting, so users may have to read between lines. All stakeholders should be more cautious about the reliability of financial and non-financial information and the disclosure tone manipulation practices that may arise in narrative reports.

Originality/value
This research contributes to the debate around CSR from an impression management perspective. To the best of the authors’ knowledge, this study is one of the first to associate CSR with, both, disclosure TM and EM in a regulated context.
Factors inhibiting the adoption of industrial revolution 4.0 in Malaysian construction industry
Authors: Almatari Husam Abdullah Qasem , Chan Melissa , Masrom Md Asrul Nasid 
Published: August 2023

PurposeThe construction industry is a major economic driver in Malaysia, playing a pivotal role in the developing nations economic growth. Malaysia's reliance on labor-driven construction practices often sees local industry lagging in adopting technological advancements common to the construction sector on a global scale. This study investigates the challenges faced by project players in using new construction industrial revolution (IR) 4.0 technologies and the difficulties in implementing these technologies in construction projects.Design/methodology/approachA quantitative survey was distributed to 183 practitioners in the Malaysian construction industry. The collected data (N = 121) has been analyzed using statistical software to calculate relative importance index values for the identified factors. A triangulation approach to validate the factors obtained from the survey was conducted with an expert group to ensure there were no additional considerations identified in the study.FindingsThe study results show that the main factors in adopting construction IR 4.0 technologies are 1) high implementation costs, 2) hesitation to adopt technologies, 3) lack of standards, 4) legal and contractual uncertainty and 5) complexity. By investigating these factors, cost and regulation issues can gradually be resolved, with construction firms implementing new technologies, educating workers and ensuring government involvement in training for skill development to support IR 4.0.Originality/valueThe outcome of these efforts to resolve construction productivity would be beneficial in their industry impact on practice and digital transformation. Additionally, the results add to the body of knowledge for construction practitioners and technology developers to work together efficiently on the implementation of construction 4.0 technologies.
A case of drug‐induced hypersensitivity syndrome complicated with fulminant type 1 diabetes and type 2 myocardial infarction
Authors: Kobayashi Yuki , Adachi Takeya , Arakawa Hiroki , Minakata Yugo , Yajima Ken , Inazumi Toyoko 
Published: August 2023

AbstractDrug‐induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is a type of drug eruption that causes multiorgan disorders after the administration of certain drugs such as anticonvulsants. Herein, we report the case of a 66‐year‐old man with DiHS/DRESS complicated by fulminant type 1 diabetes (FT1D), shock, and cardiac involvement who was treated conservatively without systemic corticosteroid administration. He had taken carbamazepine for trigeminal neuralgia for 7 weeks until he noticed eruptions on his trunk. Two days after admission, he developed diabetic ketoacidosis, resulting in hypovolemic shock. The patient was diagnosed with FT1D, and insulin was administered. Additionally, the patient had a fever over 38°C, elevated white blood cells (>20 000/μL), liver dysfunction, atypical lymphocytes, and lymphadenopathy, but no evidence of viral reactivation. The lymphocyte transformation test for carbamazepine was positive, and human leukocyte antigen typing revealed the A31:01 haplotype, a risk factor for carbamazepine‐induced cutaneous adverse drug reactions. Collectively, a diagnosis of atypical DiHS and a definitive case of DRESS was made. Moreover, myocardial dysfunction wall motion was observed. A close examination revealed mild coronary artery stenosis, leading to a diagnosis of type 2 myocardial infarction due to relative ischemia. The patient was carefully monitored without systemic corticosteroid administration because both clinical findings and laboratory data peaked on the same day. The patient's eruption and general condition improved, and he was discharged 4 weeks later. While most cases of DiHS/DRESS with cardiac involvement present with myocarditis, the possibility of ischemic heart disease should be considered in patients with cardiac involvement under shock.
Remittances and emerging African economies' growth nexus in a post COVID‐19 era
Authors: Offor Kenechukwu Onochie , Ngong Chi Aloysius , Onyejiaku Chinyere C. , Enemuo Joy , Ugbam Charles Ogechukwu , Ibe Godwin Imo , Onwumere Josaphat U. J. 
Published: August 2023

AbstractThis article aims to study the relationship between remittances and economic growth in African emerging economies from 1990 to 2021. The study centers on the optimistic, pessimistic, and the dual‐gap theories. The autoregressive distributed lag and cointegration techniques are applied. The findings indicate that remittances have a nonsignificantly negative effect on the gross domestic product growth rate. Domestic credit to the private sector and the inflation rate negatively influence economic growth. Policymakers should prioritize targeted response to the COVID‐19 crisis by reducing the costs of access to vaccines and healthcare for the populace so that the received remittances should significantly improve the population's welfare positively. Governments should recognize remittance services and reduce remittance costs by reducing taxes on remittances. Governments should increase the formalization of remittance transfers to improve accessibility to financial services to decrease the unbanked population. The monetary authorities should establish remittance‐based policies that promote the use of formal channels, ease the pressure on emerging countries' credit services, and improve foreign exchange rates. Banks should create financial products and services that attract investments and growth for the remittances of diasporas in developing economies.
Field‐portable detection of fentanyl and its analogs: A review
Authors: Crocombe Richard A. , Giuntini Greg , Schiering David W. , Profeta Luisa T. M. , Hargreaves Michael D. , Leary Pauline E. , Brown Christopher D. , Chmura Jessamyn Ward 
Published: August 2023

AbstractThe need to detect fentanyl and its analogs in the field is an important capability to help prevent unintentional exposure or overdose on these substances, which may result in death. Many portable methods historically used in the field by first responders and other field users to detect and identify other chemical substances, such as hazardous materials, have been applied to the detection and identification of these synthetic opioids. This paper describes field portable spectroscopic methods used for the detection and identification of fentanyl and its analogs. The methods described are automated colorimetric tests including lateral flow assays; vibrational spectroscopy (mid‐infrared and Raman); gas chromatography–mass spectrometry; ion mobility spectrometry, and high‐pressure mass spectrometry. In each case the background and key details of these technologies are outlined, followed by a discussion of the application of the technology in the field. Attention is paid to the analysis of complex mixtures and limits of detection, including the required spectral databases and algorithms used to interrogate these types of samples. There is also an emphasis on providing actionable information to the (likely) non‐scientist operators of these instruments in the field.
Equilibrium uniqueness in entry games with private information
Authors: Espín‐Sánchez José‐Antonio , Parra Álvaro , Wang Yuzhou 
Published: August 2023

AbstractWe study equilibria in static entry games with single‐dimensional private information. Our framework embeds many models commonly used in applied work, allowing for firm heterogeneity and selective entry. We introduce the notion of strength, which summarizes a firm's ability to endure competition. In environments of applied interest, an equilibrium in which entry strategies are ordered according to the firms' strengths always exists. We call this equilibrium herculean. We derive simple and testable sufficient conditions guaranteeing equilibrium uniqueness and, consequently, a unique counterfactual prediction.
Independent and combined effects of methamphetamine use disorders and APOEε4 allele on cognitive performance and brain morphometry
Authors: Wang Hannah A. , Liang Hua‐Jun , Ernst Thomas M. , Nakama Helenna , Cunningham Eric , Chang Linda 
Published: August 2023

AbstractAimsPrior studies showed that methamphetamine (METH) users had greater than normal age‐related brain atrophy; whether having the apolipoprotein E (APOE)‐ε4 allele may be a contributory factor has not been evaluated. We aimed to determine the independent and combined effects of chronic heavy METH use and having at least one copy of the APOE‐ε4 allele (APOE‐ε4+) on brain morphometry and cognition, especially in relation to aging.MethodsWe compared brain morphometry and cognitive performance in 77 individuals with chronic heavy METH use (26 APOE‐ε4+, 51 APOE‐ε4−) and 226 Non‐METH users (66 APOE‐ε4+, 160 APOE‐ε4−), using a 2 × 2 design (two‐way analysis of co‐variance). Vertex‐wise cortical volumes, thickness and seven subcortical volumes, were automatically measured using FreeSurfer. Linear regression between regional brain measures, and cognitive scores that showed group differences were evaluated. Group differences in age‐related decline in brain and cognitive measures were also explored.ResultsRegardless of APOE‐ε4 genotype, METH users had lower Motor Z‐scores (P = 0.005), thinner right lateral‐orbitofrontal cortices (P < 0.001), smaller left pars‐triangularis gyrus volumes (P = 0.004), but larger pallida, hippocampi and amygdalae (P = 0.004–0.006) than nonusers. Across groups, APOE‐ε4+ METH users had the smallest volumes of superior frontal cortical gyri bilaterally, and of the smallest volume in left rostral‐middle frontal gyri (all P‐values <0.001). Smaller right superior‐frontal gyrus predicted poorer motor function only in APOE‐ε4+ participants (interaction‐P < 0.001). Cortical volumes and thickness declined with age similarly across all participants; however, APOE‐ε4‐carriers showed thinner right inferior parietal cortices than noncarriers at younger age (interaction‐P < 0.001).ConclusionsChronic heavy use and having at least one copy of the APOE‐ε4 allele may have synergistic effects on brain atrophy, particularly in frontal cortices, which may contribute to their poorer cognitive function. However, the enlarged subcortical volumes in METH users replicated prior studies, and are likely due to METH‐mediated neuroinflammation.