bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between upper extremities functional recovery with speech recovery among post stroke patients - an observational study
Authors: Das P. , Thakkar D. , Sudhan S.G. , Zeeshan A. , Reddy S.M. 
Published: March 2023

Globally stroke is one of the most common neurological disease, frequently causing death and disability. The survivors suffer from various impairments among which upper and lower limb motor deficits, visuo-spatial neglect and speech impairments are most common. The aim of the study is to find out the association between upper extremity functional recovery and speech recovery in acute stroke patients and to predict the recovery of upper extremity functions based on recovery of speech. Twenty-eight eligible and willing subjects diagnosed with dominant hemisphere supratentorial stroke were taken for the study. The objectives were achieved with Fugl- Meyer assessment: upper extremity (FMA-UL), Western Aphasia Battery (WAB) scale and Wolf motor function scales (WMFT), that were administered by the tester on the eligible subjects within a week after acute stroke and follow up measurements were carried out post one month. A moderate positive correlation was found in between WMFT and WAB. Strength component of WMFT was found to show better correlation with WAB as compared to functional ability and time components. Since initial recovery is mostly seen within (90-120) days, a long term follow up of the same study may provide more information regarding return of upper extremity function with respect to speech. Hence, recovery of speech can predict upper extremity functional recovery.
The impact of preoperative stress on individuals' experience of postoperative complications after undergoing cardiac surgery
Authors: Prahlad P. , Vyas N.L. , Singh N.K. 
Published: March 2023

Objective: This study aimed to measure preoperative stress in all patients undergoing cardiac surgery and to examine the relationship between preoperative stress and postoperative complications. Material and methods: The prospective study placed from Mar 2018-Dec 2019 at a single academic medical center. One hundred adults aged 18 to 65 who had undergone cardiac surgery consecutively were included in the analysis. The State Anxiety Inventory was used to quantify preoperative stress and assess its relationship to both postoperative pain and morphine usage. Result: The patient population is 67% men and 33% women, with an average age of 57 and 10 years. Before surgery, 66% of patients said they felt only a little bit of anxiety, while 34% said they were extremely anxious. Patients reporting moderate to severe anxiety (SA) before surgery had significantly higher mean pain ratings than patients reporting mild anxiety (MA). Patients who had moderate SA used much more morphine both during the procedure and thereafter than patients who did not experience stress. Conclusion: After cardiac surgery, patients that had moderate to severe stress before the procedure reported considerably greater levels of discomfort compared to that who had MA. Patients need greater analgesia postoperatively in addition to during surgery.
Clinical variables and pre-operative depression levels for prediction of pain severity in patients undergoing heart surgery
Authors: Gupta P. , Sarkar P. , Upadhyaya S.K. 
Published: March 2023

Objective: In patients undergoing heart surgery, severe pain is common and may raise the risk of heart conditions, morbidity, and death. The study's goals were to evaluate post-cardiac surgery pain predictors, such as clinical variables and depression, as well as perioperative Pain Severity (PS). Methods: The research included 98 heart surgery patients in total. PS was analysed utilizing a Numerical Rating System (NRS). From the second day after surgery through the seventh day, pain levels were monitored daily. Clinical data was obtained, and depression levels were determined utilizing the Center for Epidemiological Study of Depression (CES-D). Results: From pre-operative levels, pain severe dramatically increased while hospitalized, peaking at day 2 after surgery. Higher CES-D preoperative values in gender, heart function, smoking, and a high Body mass index (BMI). Preoperative CES-D ratings were considerably higher for patients in severe pain than for those with no pain or mild pain. Patients experiencing severe pain (NRS 7 to 10) exhibited considerably greater white blood cell (WBC) counts than those free of pain or mild pain (NRS 0 to 6) (p=0.01). However, there was no association between maximum WBC levels after surgery and CES-D scores. Conclusion: Following surgery, PS considerably increased and was linked to depressive symptoms, gender, heart function, BMI, and smoking. These variables could be used as a starting point for detection and treatment to help stop the progression of acute pain into chronic pain.
Variabilidad genética y rol de los fenotipos oculares en el Síndrome de Stickler
Authors: Pantaleon Florido Gretta , Juvier Riesgo Tamara 
Published: March 2023

Introducción: El Síndrome de Stickler (SS) es una anomalía del tejido conectivo que se caracteriza por alteraciones oculares, orofaciales, auditivas y esqueléticas. Aunque existen cuatro tipos de SS, la mayoría de las formas clínicas presentan alteraciones oculares como alta miopía, degeneración vitreorretiniana, cataratas y desprendimiento de retina, siendo la causa más común de este último en la infancia.
Objetivo: Ampliar los conocimientos acerca de los genes involucrados en el SS y su expresión clínica, profundizando en el rol de los fenotipos oculares.
Metodología: En este trabajo realizamos una revisión del estado actual del SS consultando bibliografía de alto impacto y reciente publicación. Se hicieron búsquedas a través de PubMed, Hinari, SCIELO, Medline y se consultaron páginas dedicadas a estos temas como OMIM, OPHRANET, GeneMap, Genetest, Proteins, Gene, entre otros. Se utilizaron descriptores de búsqueda como “Síndrome de Stickler’’, ‘‘Stickler Syndrome gene’’, ‘‘ocular signs and Stickler Syndrome’’ and ‘‘Stickler Syndrome review’’.
Resultados: Fueron encontrados numerosos artículos acerca del SS, de ellos se citaron un total de 32, de los cuales 25 son del 2016 a la fecha, reportándose 4 genes principales: COL2A1, COL11A1, COL9A1, COL9A2. El COL2A1 y el COL11A1 son responsables del 95% de los pacientes con SS. Las alteraciones oculares son comunes en la mayoría de los tipos.
Conclusiones: El diagnóstico del SS se basa en criterios clínicos-radiológicos y aunque la confirmación molecular es determinante, la evaluación del vítreo puede ser una guía útil para un análisis genético eficiente.
Is a standard intravenous patient-controlled analgesia protocol sufficient for patients with bilateral knee arthroplasty?
Authors: GÜRSOY ÇİRKİNOĞLU Gözde , MALTEPE Fikret , KARATOSUN Vasfi , ÖZBİLGİN Şule , ÜNVER Bayram , DENİZ Ayten 
Published: March 2023

The aim of this study is to investigate whether patients undergoing one-stage bilateral total knee arthroplasty and those undergoing unilateral total knee arthroplasty differed in their responses to a standard intravenous patient-controlled analgesia protocol. Data from patients with the physiological status I-III according to American Society of Anesthesiologists, aged 18-99 years, undergoing one-stage bilateral or unilateral total knee arthroplasty under spinal anesthesia between January 2014 and December 2017 and offered a standard intravenous patient-controlled analgesia with morphine were retrospectively reviewed. Demographic data, Visual Analogue Scale scores and postoperative complications were examined. The total dose of analgesics consumed, analgesia demands, doses delivered and the ratio of delivered doses to demands in 0- 24 hours and 24-48 hours after surgery available in the patient-controlled analgesia pump monitoring forms were recorded.
Records about 68 patients who had one-stage bilateral total knee arthroplasty and 124 patients who had unilateral total knee arthroplasty were accessed. The analgesia demands and analgesic doses delivered and utilized by the patients with one-stage bilateral total knee arthroplasty were significantly higher in 0-24 hours and 24-48 hours after surgery. Side-effects of the analgesia were similar in both groups. Visual Analogue Scale scores in 24-48 hours after surgery were higher in the patients with unilateral total knee arthroplasty.
Although the patients with one-stage total knee arthroplasty received significantly higher doses of morphine, side-effects due to this opioid did not differ significantly. This showed that the standard intravenous patient-controlled analgesia protocol utilized was reliable and effective in both patient groups.
PROSTAT KANSERİNİN HACİMSEL MODÜLASYONLU ARK TEDAVİSİ İLE RADYOTERAPİSİNDE BİLGİ TABANLI PLANLAMA YÖNTEMLERİNİN KULLANILDIĞI KLİNİK ÇALIŞMALARIN DEĞERLENDİRİLMESİ
Authors: KINAY Şeyda , AKÇAY Doğukan , UMAY Cenk , AYDIN Barbaros , GÜLŞAN Dilara , AKGÜNGÖR Kadir , DEMİRAL Ayşe Nur 
Published: March 2023

Bilgi Tabanlı Planlama (“Knowledge Based Planningˮ-KBP), klinik olarak kabul edilebilir Yoğunluk Ayarlı Radyoterapi (“Intensity Modulated Radiotherapy”-IMRT) ve Hacimsel Modülasyonlu Ark Tedavisi (“Volumetric Modulated Arc Therapy”-VMAT) planlarını minimum iş akışıyla optimize etmek için bilgi tabanlı modeller (“Knowledge Based Model”–KBM) kullanarak plan kalitesini standart hale getirmeyi amaçlar. KBP, Risk Altındaki Organlar (‟Organ at Risk”-OAR) için ulaşılabilir Doz-Volüm Histogramı (DVH)’nı tahmin eder ve her bir yeni hasta için ideal optimizasyon hedefleri sağlar. KBP modeli, plan kalitesini iyileştirir, plan tutarlılığını koruyarak planlayıcılar arası değişkenliği azaltır ve simülasyondan tedavi başlangıcına dek geçen süreyi kısaltır.
Bu derlemede prostat kanserinin VMAT tekniği ile tedavisinde KBP tabanlı yöntemlerin kullanıldığı klinik çalışmaların sonuçları incelendi. “Knowledge-based treatment planning”, “prostate cancer”, “VMAT” anahtar kelimeleri kullanılarak “PubMed” tarama motorunda “Clinical Trial” kategorisindeki İngilizce olarak yayınlanmış makalelerin taranması sonucu ulaşılan beş adet çalışma derleme kapsamına alındı.
Bu klinik çalışmaların tümünde temelde KBP modelinin dozimetrik ve mekanik performansını değerlendirmek ve optimize etmek istenmiştir. Bu nedenle her bir kliniğin deneyimine göre hazırlanan manuel planlar, KBP ile oluşturulan otomatik planlar ile karşılaştırılmıştır. Prostat kanserinin VMAT planlamasında KBP kullanımı, doğrulama çalışmalarında, güçlü bir şekilde performans göstermiştir. KBP yöntemleri, plan kalitesi açısından genellikle uzman seviyesindeki planlayıcılara eşdeğerdir ancak ön sonuçlar, önemli ölçüde daha gelişmiş olduklarını göstermektedir. Hedef volüm ile örtüşen OAR volümlerinin dikkate alındığı KBP modellerinin örtüşme volüm histogramı (“overlap volüme histogram”-OVH) rehberliğinde daha hassas ve doğru doz tahminleri yapabileceği düşünülmektedir. KBP yöntemlerinin uygulaması sırasında dozimetrik ve mekanik performansın yanı sıra hastaya özgü kalite güvenirliğini (“Quality Assurance” –QA) doğrulamak da çok önemlidir.
Relationship of Shear-wave Elastography Findings with Breast Cancer Molecular Subtypes and Comparison with Other Radiological Imaging Techniques
Authors: ASLAN Özge , OKTAY Ayşe Nur 
Published: March 2023

Purpose: We aimed to evaluate the shear-wave elastography (SWE) findings of breast cancer and to compare their differences with other imaging techniques and to determine the rela-tionship between molecular subtypes.
Methods: Radiological findings and histopathology results of patients who underwent biopsy due to breast mass and diagnosed as malignant were evaluated retrospectively. SWE findings, ultrasonography (US), mammography and magnetic resonance imaging (MRI) findings were evaluated. The histo-pathology results of the tru-cut biopsy performed under the guidance of US-SWE were analyzed. The findings of SWE and other radiological techniques were compared statistically and relationship with molecular subtypes was evaluated.
Results: We had 51 patients with a median age of 58 years. In SWE, the mean tumor size was 20 mm, and the tumor elasticity was 105 kPa. Statistically signi-ficant correlation was found between the tumor size differences measured by B mode US-SWE and the tumor elasticity value. No correlation was found between SWE findings and molecular subtypes. SWE had significantly high positive correlation with mamography and MRI in terms of lesion size, with US very high positive correlation and with ER positivity weak negative correlation.
Conclusion: In addition to conventional radiological imaging techniques the use of SWE provides useful insight to evaluation of breast cancer.
La vinculación social universitaria: un camino hacia la pertinencia social
Authors: Seañez Martínez Zaide Patricia , Guadarrama Atrizco Víctor Hugo 
Published: March 2023

Historically, universities have been a key element of socio-economic, political and technological development of nations. This fact has required a clear and effective relationship with society, which has commonly been called as linkage. Given the importance of this link, the purpose of this article is to review the evolution of the term in order to know what the analysis has focused on, so it allows us to identify the degree of social dimension importance in this relationship. To achieve this task, a historical-theoretical review is carried out of the conception of the university linkage with its environment. This review shows that there is little consensus on how to call it and define it, since there is a risk of falling into generalizations or reductionisms. The study of university-company linkage has been privileged, so this paper proposes the concept of university social linkage as an approach to examine how universities interact with other social actors and towards all areas of reality. It is relevant to highlight that university linkage is a strategy for social relevance, which it is not explored in depth in this document, but is outlined as a future line of research.
Keywords: University; Linkage; Social relevance
Imaginando el futuro: ejes centrales para un modelo de Responsabilidad Social Universitaria
Authors: González Rodríguez Guillermo Isaac 
Published: March 2023

The university mission is a subject of debate that has been considered for some decades, as something that must be reformed to meet the needs of different contexts. This paper makes an approach to the role that universities assume with respect to their mission and their substantive functions in order to assimilate social problems and thus respond to the Sustainable Development Goals (SDG). The objective is to describe the main elements that are found around a model of USR in order to face the postmodern stage. For this, the 2030 agenda of the United Nations (UN) is taken as the central axis, as well as the positions of social knowledge management and the USR for the analysis. As results, a series of elements are offered that can serve as the basis for the formulation of a Model of social use of knowledge through the development of projects from the university that are applicable to the social environment and with which it is promoted in the academic community and student, an awareness of the problems that must be addressed as a priority according in the different social spheres.
Keywords: Mission; University Social Responsibility; Sustainable development goals; Social management of knowledge; University.
Desarrollo sostenible en organizaciones y la innovación
Authors: García Muñoz Aparicio Cecilia , Navarrete Torres María del Carmen 
Published: March 2023

The purpose of this research is to systematize the experience accumulated between the years 2017 and 2020 developed by the Faculty of Economics of the National University of Piura in its interaction with rural communities, based on evidence from two Populated Centers: Coyona and Yahuanduz, with the purpose of contributing to improve their living conditions. Said purpose is framed in the work of the university from the University Social Responsibility (USR); and focused from the third great mission of the university: the transfer of knowledge and the return to society. Under this proposal, it is inferred that communities not only find problems, but also solutions, which must be configured from technology and social innovation; and, be oriented towards rural spaces through capacity building and community participation. Under this proposal, a social construction based on community development prototypes should be sought, which recognizes previous knowledge and manages to insert itself into the work of the Faculty of Economics to configure a replicable and sustainable mode of interaction.
Keywords: university-community, innovation and social technology, community knowledge
Efektivitas Beberapa Jenis Feromon Organik Sebagai Atraktan Lalat Buah Pada Tanaman Cabai
Authors: Andiko Fendi , Pramudi Muhammad Indar , Soedijo Samharinto 
Published: March 2023

Red chili (Capsicum annuum L.) is a commodity that has high economic value, but the potential loss experienced in chili cultivation is also quite high, because chili is quite vulnerable to fruit fly pests. This study aims to determine the response of fruit flies to the use of pheromones derived from various kinds of fruit peels and flesh added with yeast (organic pheromones). This research took place on chili farmers' land located in the village of Tambak Langsat, West Ulin Platform, Banjarbaru City. This study used a randomized block design (RBD) with 11 treatments including the control. The results showed that the treatment given organic pheromones was able to trap fruit flies. Of all the pheromones that were most effective at getting lots of fruit flies was the chili pheromone (0.2 ml) with a catch of 25 individuals and for organic pheromones that were less effective was the mango pheromone (0.2 ml) with a catch of 4 individuals. The type of fruit fly B. dorsalis dominates of the four species with the Diversity Index (H´) of fruit flies being classified as moderate, namely 1.1082, the Dominance Index (D) being high 1 and for fruit flies dominating B. dorsalis.
Uji Efektivitas Ekstrak Kulit Jengkol (Pithecellobium jiringa) Dalam Menghambat Penyakit Antraknosa (Colletotrichum sp.) Pada Tanaman Cabai Rawit (Capsicum frutescens L.)
Authors: Astika Nor , Fitriyanti Dewi , Aidawati Noor 
Published: March 2023

The productivity of cayenne pepper in South Kalimantan has increased in 2017 – 2020, to maintain the stability of cayenne pepper productivity in South Kalimantan, efforts are needed to prevent the occurrence of cayenne pepper anthracnose. Anthracnose disease caused by the fungus Colletotrichum sp. which is an important disease in cayenne pepper because it can cause crop failure. Farmers generally control anthracnose using synthetic pesticides, but the use of synthetic pesticides can have a negative impact on the environment and crop quality. Alternative environmentally friendly controls that can be developed are the use of organic materials, especially organic wastes which still have active compounds and have the potential to be used as vegetable pesticides. One of the organic wastes that can be used is jengkol peel (Pithecellobium jiringa). The purpose of this study was to determine the effectiveness of jengkol peel extract in inhibiting the growth of the fungus Colletotrichum sp. on chili peppers. The environmental design used in this study was a one-factor completely randomized design (CRD) consisting of 5 concentrations of jengkol peel extract, namely T0 (control), T1 (10%), T2 (20%), T3 (30%), and T4 (40%) with 4 replications. The application of jengkol peel extract was carried out 3 times and the inoculation of the fungus Colletotrichum sp. done 1 time when the plants are flowering (50 hst). Observations were made every 7 days after the application of jengkol peel extract. The results of research observations showed that jengkol peel extract was effective in inhibiting the occurrence of anthracnose disease. The concentration of jengkol peel extract that was most effective in inhibiting the growth of anthracnose disease in cayenne pepper was at a concentration of 40% with the smallest percentage of disease incidence of 12.9%.
Kemampuan Jenis PGPR dalam Menekan Serangan Nematoda Puru Akar (Meloidogyne spp.) pada Tanaman Seledri (Apium graveolens L.)
Authors: Hadijah Siti , Liestiany Elly , Aidawati Noor 
Published: March 2023

Celery plant (Apium graveolens L.) is a cultivated plant that has high economic value, usually used as food flavoring, cooking seasoning and can also be used as a dish garnish. Functions for health such as drugs to lower high blood pressure for people with hypertension. One pest that can affect the quality and quantity of celery production is root knot nematode (NPA) caused by Meloidogyne spp. This study aims to determine the ability of PGPR species to suppress root knot nematodes (Meloidogyne spp.) on celery. This study was designed using a one-factor Completely Randomized Design (CRD). The factor tested was the effect of giving PGPR types namely elephant grass root, kalakai root, fern root and bamboo root. There were 5 treatments and 4 replications. The results showed that giving PGPR could reduce the intensity of root knot attacks and reduce nematode populations in the soil around the roots, as well as significantly affect the number of leaves (stalks) of celery at the age of 58 and 72 days after planting (dap) and weight. wet celery at the age of 44, 58 and 72 dap.
Chemical Literacy Ability in Gender Perspective on Acid-Base Material
Authors: Saputri Erlinda Novriani , Laksono Pandu Jati , Wigati Indah 
Published: March 2023

Research on chemical literacy skills from a gender perspective on acid-base materials has been conducted at SMA Y in Lahat District. This study aimed to determine students' chemical literacy skills from a gender perspective in acid-base material. This type of research is descriptive research with a qualitative approach. The subjects of this study were 28 students of class XI MIPA 1 at SMA Y in Lahat Regency, with 14 male and 14 female students. The instruments in this study were chemical literacy test questions in the form of descriptions and interview guidelines. The results of this study indicate that the chemical literacy ability of SMA Y students in the Lahat Regency is, on average, 56% in the low category. The difference in chemical literacy based on gender for male students is 54%, and for female students is 59%. The chemical literacy of female students is better than male students, with a difference of 5%, and is included in the low category. Female students were better able to answer questions that explained the concept of acids and bases, while male students were better able to answer questions on acid-base calculations