bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three-way species interactions reverse the positive pairwise effects of two natives on an exotic invader
Authors: Schlau Benjamin M. , Huxman Travis E. , Mooney Kailen A. , Pratt Jessica D. 
Published: March 2023

AbstractThe disruptive effects of tertiary species on otherwise positive pairwise species interactions (e.g. context-dependent parasitism in pollinator syndromes) is well-known. However, few—if any—studies have investigated how invasive plants affect interactions between facilitative plants and their native plant communities. Further, if tertiary invasive species can change interactions among native species from positive to negative, then a tertiary native should be capable of the same phenom for pairwise interactions between natives and invasives. Our previous research indicates invasive black mustard (Brassica nigra) changes interaction signs for otherwise positive species interactions between the dominant, native facilitator California buckwheat (Eriogonum fasciculatum) and its co-dominant beneficiary California sagebrush (Artemisia californica) in semi-arid California coastal sage scrub habitat. Here, E. fasciculatum and A. californica seedlings increased B. nigra shoot growth in pairwise species interactions in the greenhouse. However, in three-way species interactions, E. fasciculatum and A. californica together reduced B. nigra SLA, height, and reproductive potential while not increasing shoot DW. In three-way species interactions, B. nigra did not significantly reduce E. fasciculatum facilitation of A. californica. Also surprisingly, light competition with B. nigra resulted in an increase in A. californica height, which reduced the negative effects of A. californica light competition on shade-intolerant E. fasciculatum. In an additive field experiment, A. californica protected E. fasciculatum from facilitating germination and growth of B. nigra when water competition was minimized. Taken together, this study demonstrates the importance of studying species interactions between competitive, native perennials in the current ecological context of invaded ecosystems.
Improving capacity for phytoremediation of Vetiver grass and Indian mustard in heavy metal (Al and Mn) contaminated water through the application of clay minerals
Authors: Otunola Beatrice Omonike , Aghoghovwia Makhosazana P. , Thwala Melusi , Gómez-Arias Alba , Jordaan Rian , Hernandez Julio Castillo , Ololade Olusola Oluwayemisi 
Published: March 2023

Abstract
One of the consequences of mining is the release of heavy metals into the environment, especially water bodies. Phytoremediation of areas contaminated by heavy metals using Vetiver grass and Indian mustard is cost-effective and environmentally friendly. This study aimed at enhancing remediation of heavy metal contaminated water through the simultaneous hybrid application of clay minerals (attapulgite and bentonite) and Vetiver grass or Indian mustard. A 21-day greenhouse experiment was carried out to investigate the effectiveness of the clay minerals to improve heavy metal phytoremediation. The highest accumulation of aluminium (Al) by Vetiver grass was 371.8 mg/kg in the BT2.5VT treatment, while for Mn, the highest accumulation of 34.71 mg/kg was observed in the AT1VT treatment. However, Indian mustard showed no significant uptake of heavy metals, but suffered heavy metal toxicity despite the addition of clay minerals. From this study, it was evident that bentonite added at 2.5% (w/v) could improve the phytoremediation capacity of Vetiver grass for Al and Mn polluted water. The current laboratory-scale findings provided a basis for field trials earmarked for remediation in a post-mining coal environment in South Africa. This remediation approach can also be adopted in other places.
Climate impact of bioenergy with or without carbon dioxide removal: influence of functional unit and parameter variability
Authors: Zakrisson Lisa , Azzi Elias S. , Sundberg Cecilia 
Published: March 2023

Abstract
Purpose
Bioenergy with carbon dioxide removal (CDR) is increasingly proposed as an efficient way to mitigate climate change. This study examined the circumstances and methodological choices in which two CDR bioenergy systems were preferable to a reference bioenergy system from a climate change mitigation perspective. The CDR systems were also compared.

Methods
Three systems were modelled: two CDR systems (Biochar, bioenergy with carbon capture and storage (BECCS)), with a combined heat and power (CHP) system as reference. A parameterised life cycle inventory (LCI) model was developed and computed for all systems and four different functional units (FUs), resulting in different distributions of climate impacts. Contribution analysis was performed, followed by pair-wise comparison of all scenarios to establish their ranking. First-order Sobol indices were computed to assess the contribution of each parameter to total variance. When ranking of scenarios was strongly dependent on parameter values, decision tree analysis was applied.

Results and discussion
The CDR systems had a lower climate impact than CHP in most computations, across all FUs. On comparing the two CDR systems, the preferable system changed with FU. With heat or carbon sequestration as FU the Biochar system was preferable in general, while with electricity or biomass use as FU, the BECCS system had the lowest climate impact in most computations. For most system configurations, energy substitutions had a large influence and contributed most to the variance in results. The system ranking also depended on the reference activities in the background energy system.

Conclusions
The Biochar and BECCS systems were generally preferable to the reference CHP system from a climate mitigation perspective, particularly when the reference energy systems had a relatively low climate impact. However, FU and parameters affected the system ranking. For comparing BECCS and biochar, case-specific climate impacts will be decisive, but not always conclusive, as the choice of FU has such large impact on the results.

Recommendations
When conducting LCA of multi-functional systems, the use of several FUs, parameterised LCI, and contribution analysis allows for deeper investigation than conventional sensitivity analyses. When analysing the climate impact of bioenergy with or without carbon removal, it is especially important to perform sensitivity analysis on the energy background system, since it strongly affects the results.
Integration of consumer preferences into dynamic life cycle assessment for the sharing economy: methodology and case study for shared mobility
Authors: Fernando Chalaka , Buttriss Gary , Yoon Hwan-Jin , Soo Vi Kie , Compston Paul , Doolan Matthew 
Published: March 2023

Abstract
Purpose
The rising of the sharing economy (SE) has lowered the barrier of purchase price to accessing many different products, thus changing the consumer decision paradigm. This paper addresses the challenge of assessing the life cycle impacts of SE systems in the context of this new consumer decision-making process. The paper proposes a methodological framework to integrate consumer preferences into the Dynamic Life Cycle Assessment (dynamic-LCA) of SE systems.

Methods
In the proposed consumer preference integrated dynamic-LCA (C-DLCA) methodological framework, system dynamics (SD) is used to combine consumer preference and the principal method, dynamic-LCA, which follows the ISO 14040 LCA framework. Choice-based conjoint analysis (CBCA) is chosen as the stated preference tool to measure consumer preference based on SE alternatives, attributes and attribute levels. CBCA integrates discrete choice experiments (DCE) and conjoint analysis features. Random utility theory is selected to interpret the CBCA results by employing multinomial logistics as the estimation procedure to derive the utilities. Derived utilities are connected in iterative modelling in the SD and LCA. Dynamic-LCA results are determined based on dynamic process inventory and DCE outcomes and then interpreted aligned with the SD policy scenarios.

Results and discussion
The C-DLCA framework is applied to assess the GHG changes of the transition to car-based shared mobility in roundtrips to work in the USA. Carpooling and ridesourcing are selected as the shared mobility alternatives based on different occupancy behaviours. Powertrain system and body style are employed as the fleet technology attributes and the latter as an endogenous variable. Dynamic-LCA results are generated considering the high battery electrical vehicle (BEV) adoption as the policy scenario, and results are measured against a service-based functional unit, passenger-kilometre. The model outcomes show a significant reduction in aggregated personal mobility-related dynamic-GHG emissions by transitioning to car-based shared mobility. In contrast to the use phase GHG emissions, the production phase emissions show an increase. The results highlight the importance of integrating consumer preference and temporality in the SE environmental assessments.

Conclusions
The proposed C-DLCA framework is the first approach to combine consumer preferences, SD and LCA in a single formulation. The structured and practical integration of conjoint analysis, SD and LCA methods added some standardisation to the dynamic-LCAs of the SE systems, and the applicability is demonstrated. The C-DLCA framework is a fundamental structure to connect consumer preferences and temporal effects in LCAs that is expandable based on research scope.
Sheathing and Pay Techniques in the Boa Vista 1 Ship (Lisbon, Portugal)
Authors: Lopes Gonçalo C. , Petrucci-Fonseca Francisco 
Published: March 2023

AbstractBetween September 2012 and February 2013, archaeological excavations carried out in the riverside area of Lisbon (Portugal) revealed the remains of two wooden ships: Boa Vista 1 (BV1) and Boa Vista 2 (BV2), both dating from the late seventeenth or early eighteenth century. BV1 ship consists of scattered hull timbers which were damaged and out of their original positions. Some of the ship’s hull features are common in the Mediterranean like a composite keel with butt joints and hook scarfs in the connection between floors and futtocks, while others are well-known Iberian shipbuilding features like the transition between the keel and the sternpost being made through a single piece, the heel. A unique feature was a layer of animal hair between the sheathing and the hull planking. This paper focuses mainly on the study of wooden sheathing, including but not limited to the analysis of its conventional “architectural signatures”. The latest results concerning animal hair identification will also be presented and discussed, showing the added value of multidisciplinary approaches in archaeology.
Betriebliche Gesundheitsförderung (BGF) im Laufe der Zeit
Authors: Blumentritt Sebastian , Luig Teresa , Enklaar Arnold , Englert Heike 
Published: March 2023

Zusammenfassung
Hintergrund
Zur Qualitätssicherung und Weiterentwicklung von BGF-Maßnahmen (betriebliche Gesundheitsförderung) ist es von Interesse, einen Überblick über wissenschaftlich untersuchte BGF-Maßnahmen in den letzten zwei Jahrzehnten zu erlangen.

Zielsetzung
Wissenschaftlich evaluierte BGF-Maßnahmen aus den Jahren 2000–2020 werden mithilfe der in der Praxis durch den GKV-Spitzenverband eingesetzten Themenfelder auf die thematischen Entwicklungen, den Nutzen, aber auch die Schwächen für die Übertragbarkeit in die Praxis hin analysiert.

Methode
Eine systematische Literaturrecherche für den Publikationszeitraum zwischen 2000 und 2020 wurde in zwei elektronischen Datenbanken durchgeführt.

Ergebnisse
Die Einschlusskriterien erfüllten 41 Artikel. Die meisten der in den Studien durchgeführten und evaluierten BGF-Maßnahmen waren keine Einzelmaßnahmen, sondern stellten Programme dar. In ihnen wurden mehrere Themenfelder gleichzeitig adressiert. Insgesamt zeigten sich die in den Studien untersuchten BGF-Maßnahmen sehr heterogen. Zum Ende des Untersuchungszeitraumes nahm die Anzahl an Publikationen zu.

Schlussfolgerung
Die im Leitfaden Prävention vorgegebenen BGF-Themenfelder sind bis auf ein Themenfeld ausgewogen vertreten. Die Studien zu den BGF-Maßnahmen sind bezogen auf die Verständlichkeit der angewendeten Didaktik und Methodik oft nur eingeschränkt nachvollziehbar und somit schwer in die organisationale Praxis übertragbar.
Responding to Health Outcomes and Access to Health and Hospital Services in Rural, Regional and Remote New South Wales
Authors: McDonald Fiona , Malatzky Christina 
Published: March 2023

AbstractEthical perspectives on regional, rural, and remote healthcare often, understandably and importantly, focus on inequities in access to services. In this commentary, we take the opportunity to examine the implications of normalizing metrocentric views, values, knowledge, and orientations, evidenced by the recent (2022) New South Wales inquiry into health outcomes and access to hospital and health services in regional, rural and remote New South Wales, for contemporary rural governance and justice debates. To do this, we draw on the feminist inspired approach to rural health ethics involving analysis of power relationships developed by Simpson and McDonald and related ideas from critical health sociology. In presenting this analysis, we extend contemporary thought about spatial health inequities and structural violence.
Sandstorms damage the photosynthetic activities of Haloxylon ammodendron seedlings
Authors: Shi Shengbo , Zhou Dangwei , Shi Rui , Sun Tao , Wang Fanglin , Gao Xiuzhen , Zhang Yunian , Zhao Peng , Xu Gaoxing , Tang Jinnian 
Published: March 2023

AbstractHaloxylon ammodendron is a preferred shrub species for buffering against wind and fixing sand in arid sandy areas of northwest China. To determine whether sandstorms cause damage to H. ammodendron seedlings, we investigated the effects of wind-blown sands on the photosynthetic function of H. ammodendron by simulating sand-carrying wind in the wind tunnel. The results showed that photosystem II (PSII) non-photochemical quenching (NPQ) was sensitive to wind erosion, and sustained blowing of sand-carrying winds enhanced NPQ reduction. The rapidly relaxing quenching NPQf made up the majority component of NPQ; the NPQf/NPQ ratio was approximately 64.4% in the sand-free wind group and nearly 56.2% in the sand-carrying wind group. The distribution of the quantum efficiency of the excitation energy indicated that the relative proportions of the quantum yield of PSII photochemistry ΦPSII, the quantum yield of quenching due to light-induced ΦNPQ, and non-light-induced ΦNO were influenced by both wind erosion and light intensity; the sand-carrying wind resulted in a relative decrease in ΦNPQ and a corresponding increase in ΦNO. The maximum quantum efficiency of PSII photochemistry Fv/Fm was relatively stable in the sand-free wind group, with an average value of approximately 0.81. Compared to sand-free wind, sand-carrying winds caused remarkable decreases in Fv/Fm. Light intensity was the main factor affecting ΦPSII, ΦNPQ, and relative electron transport rate (rETR); there was no interaction effect between the duration of sand-carrying wind and light intensity. Taken together, wind-blown sands cause irreversible damage to the photosynthesis of H. ammodendron seedlings, which is the main factor restricting population regeneration in shelterbelts.
Customer journey management capability in business-to-business markets: Its bright and dark sides and overall impact on firm performance
Authors: Homburg Christian , Tischer Moritz 
Published: March 2023

Abstract
Business-to-business (B2B) practitioners are increasingly interested in capabilities to holistically manage touchpoints along B2B customer journeys (CJs) to remain competitive. Research in the B2B context, however, has investigated neither what constitutes such a customer journey management capability (CJMC) nor how, whether, or when it creates value. Taking a mixed-methods approach, we conceptualize and operationalize B2B CJMC as a supplier's ability to achieve superior customer value along the B2B CJ by strategically creating value-anchored customer touchpoints characterized through the implementation of consistent resource usage across internal organizational boundaries and by continuously monitoring value creation toward the individual members of the buying center. Analyzing a multisource dataset, we provide evidence that B2B CJMC has an indirect effect on firm performance (i.e., return on sales) through two opposing mechanisms (i.e., customer loyalty and customer-related coordination costs). Importantly, using survey and archival data, we show that, overall, B2B CJMC has a significant and positive impact on firm performance through the two mechanisms. Finally, these underlying mechanisms are also prevalent when testing for the moderating factors switching costs, number of touchpoints, and product versus service.
CAR-T Therapies in Solid Tumors: Opportunities and Challenges
Authors: Guzman Grace , Reed Megan R. , Bielamowicz Kevin , Koss Brian , Rodriguez Analiz 
Published: March 2023

Abstract

Purpose of Review

This review will discuss the challenges facing chimeric antigen receptor (CAR)-T cell application for solid tumors and opportunities to overcome these obstacles. In addition, this review will examine therapies that are in development for pediatric solid tumors.

Recent Findings
The similar success of CAR-T cell treatment for hematological malignancies has not been observed in solid tumors because of the hostile tumor microenvironment and tumor heterogeneity. Most strategies developed to combat these limitations emphasize combinatorial techniques that still require further testing. Preliminary results of multiple clinical trials, including GD2- and HER2-CAR-T cells, are encouraging but must be reproduced and validated on a larger scale.

Summary
CAR-T cell application in solid tumors remains challenging, and most research is in development. Several clinical trials are ongoing for pediatric solid tumors. Early results are promising but demonstrate the need for CAR-T cell modification to prevent tumor recurrence.
Integrative Analysis Revealed LINC00847 as a Potential Target of Tumor Immunotherapy
Authors: Chen Xiujuan , Zhang Le 
Published: March 2023

AbstractLung cancer is the second most commonly diagnosed cancer and the leading cause of cancer-related death. Lung adenocarcinoma (LUAD) is the most common form of lung cancer and has a low 5-year survival rate. Therefore, much more research is needed to identify cancer biomarkers, promote biomarker-driven therapy and improve treatment outcomes. LncRNAs have been reported to participate in various physiological and pathological processes, especially in cancer, and thus have attracted much attention. In this study, lncRNAs were screened from the single-cell RNA-seq dataset CancerSEA. Among them, four lncRNAs (HCG18, NNT-AS1 and LINC00847 and CYTOR) were closely associated with the prognosis of LUAD patients according to Kaplan–Meier analysis. Further study explored the correlations between these four lncRNAs and immune cell infiltration in cancer. In LUAD, LINC00847 was positively correlated with the immune infiltration of B cells, CD8 T cells, and dendritic cells. LINC00847 decreased the expression of PD-L1, immune checkpoint blockade (ICB) immunotherapy-related gene, which suggests that LINC00847 is a potential new target for tumor immunotherapy.
Death from exsanguination due to power drill injuries in a complex suicide: a case report
Authors: Ledinek Živa , Kadiš Peter , Golec Tina Čakš 
Published: March 2023

AbstractWe present a case of a complex suicide of a 66-year-old man with a history of several psychiatric disorders. He attempted to commit suicide by inflicting cut wounds on his forearms, wrists, and neck but afterwards changed the method of suicide by using an electric power drill. After several unsuccessful attempts to drill a hole in either his head, thorax, or abdomen, he managed to perforate the common carotid artery on the right side of his neck and subsequently died from exsanguination.
Experience of loneliness on well-being among young individuals: A systematic scoping review
Authors: Binte Mohammad Adib Nuryn Aqidah , Sabharwal Jagdeep Kaur 
Published: March 2023

AbstractA systematic scoping review was conducted to explore the current evidence on the experience of loneliness influencing well-being among youths. The electronic databases Scopus, APA PsycINFO, Emerald Insight and One Search were used to identify relevant studies, followed by an analysis of the text words contained in the title and abstract, and of the index terms used to describe the article. Reference lists of all shortlisted articles were searched for additional studies. 20 studies (quantitative, qualitative and mixed) published in the English language were identified for inclusion. Findings illustrate that the experience of loneliness is a complex, evolutionary process influenced by relational and environmental factors. Results from the studies identified factors that promote lower experience of loneliness and better well-being in future life stages. Future research can substantiate the issues related to young individuals being socially isolated from others for a prolonged duration.
Minimal residual disease detection by mutation-specific droplet digital PCR for leukemia/lymphoma
Authors: Shirai Ryota , Osumi Tomoo , Keino Dai , Nakabayashi Kazuhiko , Uchiyama Toru , Sekiguchi Masahiro , Hiwatari Mitsuteru , Yoshida Masanori , Yoshida Kaoru , Yamada Yuji , Tomizawa Daisuke , Takae Seido , Kiyokawa Nobutaka , Matsumoto Kimikazu , Yoshioka Takako , Hata Kenichiro , Hori Toshinori , Suzuki Nao , Kato Motohiro 
Published: March 2023

AbstractMinimal residual disease (MRD) is usually defined as the small number of cancer cells that remain in the body after treatment. The clinical significance of MRD kinetics is well recognized in treatment of hematologic malignancies, particularly acute lymphoblastic leukemia (ALL). Real time quantitative PCR targeting immunoglobulin (Ig) or T-cell receptor (TCR) rearrangement (PCR-MRD), as well as multiparametric flow cytometric analysis targeting antigen expression, are widely used in MRD detection. In this study, we devised an alternative method to detect MRD using droplet digital PCR (ddPCR), targeting somatic single nucleotide variants (SNVs). This ddPCR-based method (ddPCR-MRD) had sensitivity up to 1E-4. We assessed ddPCR-MRD at 26 time points from eight T-ALL patients, and compared it to the results of PCR-MRD. Almost all results were concordant between the two methods, but ddPCR-MRD detected micro-residual disease that was missed by PCR-MRD in one patient. We also measured MRD in stored ovarian tissue of four pediatric cancer patients, and detected 1E-2 of submicroscopic infiltration. Considering the universality of ddPCR-MRD, the methods can be used as a complement for not only ALL, but also other malignant diseases regardless of tumor-specific Ig/TCR or surface antigen patterns.