bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rare case report of pancreatic low-grade fibromyxoid sarcoma (LGFMS)
Authors: Weiler Eric J. , Murickan Thomas , Drayer Crystal N. , Samat Sajjaad H. , Kia Michael A. 
Published: July 2023

Abstract
Background
Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon neoplasm generally affecting muscle tissue. It presents rarely in abdominal viscera and even more rarely occurs in the pancreas. All types of pancreatic sarcomas are uncommon, and LGFMS is a rarer still. We present the case of an LGFMS in the pancreas. Because of its rarity, there are no guidelines for appropriate treatment or summations of the natural course of this illness.

Case presentation
We present the case of a 49-year-old female who presented with epigastric pain. She had a prior history of three episodes of acute pancreatitis many years earlier. A CT revealed a pancreatic body mass, which was biopsied. Pathology returned LGFMS. The patient underwent a distal pancreatectomy and splenectomy. She did well after the case and did not require further intervention.

Conclusion
Though it is exceedingly rare, cases of pancreatic LGFMS should be reported in order to guide clinical decisions. LGFMS has been shown to have high malignant potential in other tissues, and there is no reason to think pancreatic masses will be different. By building a body of evidence about these rare tumors, patient care will benefit.
Should I Rest or Should I Go Now? A Randomized Cross-Over Trial Comparing Fixed and Self-Selected Rest Durations in High-Intensity Interval Training Cycling Sessions
Authors: Colorni Eyal , Ohayon Evyatar , Côté Julie N. , Obolski Uri , Halperin Israel 
Published: July 2023

Abstract
Background
In high-intensity interval training (HIIT), the rest durations between intervals are commonly prescribed using a fixed approach (e.g., 30 s between intervals). An alternative is the self-selected (SS) approach, in which trainees select their resting durations. Studies comparing the two approaches report mixed results. However, in these studies, trainees in the SS condition rested for as little or as long as they wished, leading to dissimilar total rest durations between conditions. Here, for the first time, we compare the two approaches while controlling for total rest duration.

Methods
Twenty-four amateur adult male cyclists completed a familiarization session, followed by two counterbalanced cycling HIIT sessions. Each session was composed of nine, 30-s intervals, in which the goal was to accumulate as many watts as possible on an SRM ergometer. In the fixed condition, cyclists rested for 90 s between intervals. In the SS condition, cyclists had 720 s (i.e., 8  × 90 s) of rest to allocate in any way they wished. We measured and compared watts, heart rate, electromyography of the knee flexors and extensors, rating of perceived effort and fatigue, perception of autonomy and enjoyment. Additionally, a subsample of ten cyclists completed a retest of the SS condition.

Results
With the exception of perception of autonomy, which was higher in the SS condition, outcomes were highly similar in both conditions. For example, the average aggregated differences were: 0.57 (95% CI − 8.94, 10.09) for watts; − 0.85 (95% CI − 2.89, 1.18) for heart rate; and 0.01 (95% CI − 0.29, 0.30) for rating of perceived effort (on a 0–10 scale). Additionally, the retest of the SS condition resulted in a similar rest allocation pattern across the intervals and in similar outcomes.

Conclusion
Given the similarities in performance, physiological and psychological outcomes between the fixed and SS conditions, both can be equally utilized based on coaches’ and cyclists’ preferences and training goals.
Vitamin C levels of selected Philippine indigenous berries as affected by fruit maturity and processing treatment
Authors: Castillo-Israel Katherine Ann T. , Flandez Lloyd Earl L. , Tuaño Arvin Paul P. , Sartagoda Kristel June D. , Compendio Ma. Carisse M. 
Published: July 2023

AbstractThe Philippines as a tropical country is home to several indigenous berries that offer enough supply of health-promoting bioactive compounds like vitamin C. Vitamin C is an important micronutrient in the human diet that is usually supplied by fruits and vegetables. The amount of this vitamin in different products varies depending on the species, variety, maturity, processing, and other conditions. In this study, the vitamin C contents of selected Philippine indigenous berries such as bignay and lipote were evaluated as affected by fruit maturity and processing treatment. Fruits of two bignay (Antidesma bunius (Linn.) Spreng), varieties, ‘Common’ and ‘Kalabaw’, as well as of lipote (Syzygium polycephaloides (C. B. Rob.) Merr.), at three maturity stages (unripe, half-ripe, and fully ripe) were acquired in Laguna, Philippines. Samples were subjected to two processing treatments: blanched (90 ± 5 °C, 2 minutes) and steamed (105 ± 5 °C, 5 minutes), while control samples did not undergo processing treatment. The flesh and seeds were separated, lyophilized, extracted, and subjected to quantification of vitamin C using reversed-phase high performance liquid chromatography. Results showed that the vitamin C levels of both fruits were significantly affected by maturity, processing, and their interaction (P < .05). In general, a concomitant increase in vitamin C content was noted as fruit maturity progressed for both flesh and seeds (0.3 to 1.7-fold increase). Lipote seeds on the other hand, had decreased vitamin C content as maturity progresses (0.6-fold decrease). Moreover, blanching the fruits resulted in the highest retention of vitamin C in the fruit samples (247% at most). The general findings of this study indicated that the utilization of these indigenous berries for future functional product development must be accompanied by the blanching - as a pretreatment process, of the fully ripe fruits to attain enhanced vitamin C contents.
Graphical Abstract
Automatic and continuous blood pressure monitoring via an optical-fiber-sensor-assisted smartwatch
Authors: Li Liangye , Sheng Shunfeng , Liu Yunfei , Wen Jianpei , Song Changying , Chen Zhipeng , Xu Wangyang , Zhang Zhi , Fan Wei , Chen Chen , Sun Qizhen , Shum Perry-Ping 
Published: July 2023

AbstractAutomatic and continuous blood pressure monitoring is important for preventing cardiovascular diseases such as hypertension. The evaluation of medication effects and the diagnosis of clinical hypertension can both benefit from continuous monitoring. The current generation of wearable blood pressure monitors frequently encounters limitations with inadequate portability, electrical safety, limited accuracy, and precise position alignment. Here, we present an optical fiber sensor-assisted smartwatch for precise continuous blood pressure monitoring. A fiber adapter and a liquid capsule were used in the building of the blood pressure smartwatch based on an optical fiber sensor. The fiber adapter was used to detect the pulse wave signals, and the liquid capsule was used to expand the sensing area as well as the conformability to the body. The sensor holds a sensitivity of -213µw/kPa, a response time of 5 ms, and high reproducibility with 70,000 cycles. With the assistance of pulse wave signal feature extraction and a machine learning algorithm, the smartwatch can continuously and precisely monitor blood pressure. A wearable smartwatch featuring a signal processing chip, a Bluetooth transmission module, and a specially designed cellphone APP was also created for active health management. The performance in comparison with commercial sphygmomanometer reference measurements shows that the systolic pressure and diastolic pressure errors are -0.35 ± 4.68 mmHg and -2.54 ± 4.07 mmHg, respectively. These values are within the acceptable ranges for Grade A according to the British Hypertension Society (BHS) and the Association for the Advancement of Medical Instrumentation (AAMI). The smartwatch assisted with an optical fiber is expected to offer a practical paradigm in digital health.
Assessment of barriers to optimum enteral nutrition practices as perceived by critical care providers
Authors: Elmokadem Eman Mohamed , Hanna Maha Gamil , Darweesh Ebtissam Abdelghaffar , Bassiouny Ahmed Mohamed , Sabri Nagwa A. , El Borolossy Radwa Maher 
Published: July 2023

Abstract
Background
Nutritional support is a vital intervention for critically ill patients. Despite the existence of several clinical practice guidelines focused on enteral nutrition of critically ill, there is still a gap between guideline recommendations and actual nutrition practices. The purpose of this study is to understand the role of the clinical pharmacist in identifying the barriers to applying optimum enteral nutritional practices from the perspective of critical care providers. A descriptive cross-sectional design was utilized using self-administered questionnaire. A total of 90 critical care providers comprising of 3 categories: physicians (n = 30), clinical pharmacists (n = 30), and nurses (n = 30) were recruited. "The barriers to enteral feeding critically ill patients" questionnaire was used to explore the barriers that hinder them from optimal delivery of enteral nutrition.

Results
Not enough dietitian coverage during holidays was the most important barrier facing the physicians. As for the clinical pharmacists, the most important barrier was waiting for the dietitian to assess the patient. Regarding the nurses, familiarity with nutrition guidelines was the most important barrier. There was a highly significant difference between physicians, clinical pharmacists, and nurses regarding subscales’ scores and overall scores of Barriers Questionnaire except for the resources and provider attitudes.

Conclusion
Barriers to optimum enteral nutrition practices were explored with more attention on barriers regarding dietitian support and critical care providers' attitudes. This article provides the basis for the creation of interventions intended to overcome these barriers and enhance enteral nutrition practices.
Cognitive–behavioural versus cognitive–analytic guided self-help for mild-to-moderate anxiety: a pragmatic, randomised patient preference trial
Authors: Kellett Stephen , Bee Charlotte , Smithies Jess , Aadahl Vikki , Simmonds-Buckley Melanie , Power Niall , Dugen-Williams Caroline , Fallon Neil , Delgadillo Jaime 
Published: July 2023

BackgroundGuided self-help (GSH) for anxiety is widely implemented in primary care services because of service efficiency gains, but there is also evidence of poor acceptability, low effectiveness and relapse.AimsThe aim was to compare preferences for, acceptability and efficacy of cognitive–behavioural guided self-help (CBT-GSH) versus cognitive–analytic guided self-help (CAT-GSH).MethodThis was a pragmatic, randomised, patient preference trial (Clinical trials identifier: NCT03730532). The Beck Anxiety Inventory (BAI) was the primary outcome at 8- and 24-week follow-up. Interventions were delivered competently on the telephone via structured workbooks over 6–8 (30–35 min) sessions by trained practitioners.ResultsA total of 271 eligible participants were included, of whom 19 (7%) accepted being randomised and 252 (93%) chose their treatment. In the preference cohort, 181 (72%) chose CAT-GSH and 71 (28%) preferred CBT-GSH. BAI outcomes in the preference and randomised cohorts did not differ at 8 weeks (−0.80, 95% confidence interval (CI) −4.52 to 2.92) or 24 weeks (0.85, 95% CI −2.87 to 4.57). After controlling for allocation method and baseline covariates, there were no differences between CAT-GSH and CBT-GSH at 8 weeks (F(1, 263) = 0.22, P = 0.639) or at 24 weeks (F(1, 263) = 0.22, P = 0.639). Mean BAI change from baseline was a reduction of 9.28 for CAT-GSH and 9.78 for CBT-GSH at 8 weeks and 12.90 for CAT-GSH and 12.43 for CBT-GSH at 24 weeks.ConclusionsPatients accessing routine primary care talking treatments prefer to choose the intervention they receive. CAT-GSH expands the treatment offer in primary care for patients with anxiety seeking a brief but analytically informed GSH solution.
A nomogram incorporating clinical, conventional ultrasound and shear wave elastography findings for distinguishing pleomorphic adenoma from Warthin’s tumor of the major salivary glands
Authors: Su Huan-Zhong , Yang Jia-Jia , Li Zhi-Yong , Hong Long-Cheng , Lin Wen-Jin , Chen Cong , Guo Jie , Fang Zhen-Yan , Xue En-Sheng 
Published: July 2023

Objective:
Pre-operative differentiation between pleomorphic adenoma (PA) and Warthin’s tumor (WT) of the major salivary glands is crucial for treatment decisions. The purpose of this study was to develop and validate a nomogram incorporating clinical, conventional ultrasound (CUS) and shear wave elastography (SWE) features to differentiate PA from WT.

Methods:
A total of 113 patients with histological diagnosis of PA or WT of the major salivary glands treated at Fujian Medical University Union Hospital were enrolled in training cohort (n = 75; PA = 41, WT = 34) and validation cohort (n = 38; PA = 22, WT = 16). The least absolute shrinkage and selection operator (LASSO) regression algorithm was used for screening the most optimal clinical, CUS, and SWE features. Different models, including the nomogram model, clinic-CUS (Clin+CUS) and SWE model, were built using logistic regression. The performance levels of the models were evaluated and validated on the training and validation cohorts, and then compared among the three models.

Results:
The nomogram incorporating the clinical, CUS and SWE features showed favorable predictive value for differentiating PA from WT, with the area under the curves (AUCs) of 0.947 and 0.903 for the training cohort and validation cohort, respectively. Decision curve analysis showed that the nomogram model outperformed the Clin+CUS model and SWE model in terms of clinical usefulness.

Conclusions:
The nomogram had good performance in distinguishing major salivary PA from WT and held potential for optimizing the clinical decision-making process.
Maximum and mean standardized uptake values of medication-related osteonecrosis of the jaw with bone SPECT/CT: comparison of mandibular pathologies, control and temporomandibular joints
Authors: Tezuka Yasuhito , Ogura Ichiro 
Published: July 2023

Objective: Recently, single-photon emission CT/CT (SPECT/CT) plays an important role in assessing patients with medication-related osteonecrosis of the jaw (MRONJ). The aim of this study was to investigate maximum and mean standardized uptake values (SUVs) of MRONJ with bone SPECT/CT, especially comparison of mandibular pathologies, control and temporomandibular joints. Methods: 61 mandibular patients with MRONJ who underwent bone SPECT/CT were included in this study. The maximum and mean SUVs of the lesion, right and left sides of the lesion, opposite side of the lesion as control, right and left temporomandibular joints were analyzed using a workstation and software. The SUVs of MRONJ were analyzed using one-way analysis of variance with Tukey’s honestly significant difference test. Patient characteristics with MRONJ and SUVs were analyzed using Mann–Whitney U test. P-values less than 0.05 were considered to indicate statistical significance. Results: The maximum and mean SUVs for opposite side of the lesions (4.4 ± 2.0 and 1.8 ± 0.7) were significantly lower than those for mandibular lesions (18.3 ± 8.1 and 6.3 ± 2.8), right side of the lesions (8.1 ± 3.9 and 2.9 ± 1.3) and left side of the lesions (8.1 ± 3.9 and 2.8 ± 1.4), respectively. The maximum and mean SUVs for right and left sides of the lesions, and opposite side of the lesions, right and left temporomandibular joints were not significant difference. Furthermore, the maximum SUVs of the mandibular lesions were a significant difference for age and staging. Conclusions: The maximum and mean SUVs with SPECT/CT can be useful in the quantitative management of MRONJ patients.
Creation of Dimicleft radiological cleft phantom skulls using reversed virtual planning technique
Authors: Pálvölgyi Laura , Kesztyűs Artúr , Shujaat Sohaib , Jacobs Reinhilde , Nagy Krisztián 
Published: July 2023

Objectives:
The aim of this technical report was to develop customized pediatric phantoms for cone-beam computed tomography (CBCT)-related research in cleft patients.

Methods:
Six human pediatric skulls (age: 5–10 years) were recruited. A cone-beam computed tomography (CBCT) scan was taken for each skull, followed by virtual modeling through the process of segmentation. An artificial cleft was designed and printed to be applied onto the skull for the creation of an artificial cleft. The skulls were covered with non-radiopaque tape and immersed in melted Mix-D soft tissue equivalent material. The resulting phantoms covered with Mix-D were assessed radiologically by two expert radiologists. These phantoms were referred to as Dimicleft pediatric skull phantoms.

Results:
Dimicleft phantoms were able to appropriately mimic in vivo circumstances. No gaps existed between Mix-D and bony tissue. Virtual planning allowed the optimal designing of an artificial cleft onto the phantom. The artificially created cleft was suitable to determine the size, location, and extent of the cleft.

Conclusions:
Dimicleft phantoms could act as a viable alternative to other commercially available options for assessing image quality and optimizing CBCT protocols in cleft patients for diagnostics and three-dimensional treatment planning.
Taxas de câmbio e distorções contábeis nas operações de hedge
Authors: Machado Morais Gilvan , Ladeia Christovam Pietro , Vieira Cicogna Maria Paula , Menezes da Silva Ricardo Luiz , Ribeiro do Valle Maurício 
Published: July 2023

O objetivo da pesquisa é evidenciar distorções contábeis causadas pelo uso de diferentes taxas de câmbio na contabilização das operações de hedge e mostrar o hedge accounting como solução. As divergências surgem pela omissão das normas contábeis em definir a taxa de câmbio que deve ser empregada. Ilustramos, a partir de um caso, o efeito das diversas taxas cambiais sobre os demonstrativos contábeis. Os resultados revelam que os efeitos sobre o resultado e o patrimônio podem mudar dependendo do emprego do hedge accounting. Além do hedge accounting, sugere-se que os ativos e passivos em dólar dos instrumentos de hedge sejam descontados pelo cupom cambial e convertidos pela PTAX, como forma de compatibilizar com a conversão dos ativos e passivos em dólar; alternativamente, o órgão normativo brasileiro poderia divulgar uma taxa de câmbio oficial para ser empregada.
Short communications: Effect of red spinach (Amaranthus tricolor L. var Blitumbrum) extract in the diet on color brightnes of guppy fish (Poecilia reticulata)
Authors: Yusni Eri , Hasibuan Nurul F.D. 
Published: July 2023

Fish color brightness is influenced by food intake, but no prior reviews have explored the use of red spinach extract in fish feed to enhance color brightness and promote growth in guppy (Poecilia reticulata). Therefore, this study aims to determine the suitable concentration of red spinach extract Amaranthus tricolor color brightness, growth, and survival of guppy. The experiment followed a completely randomized design with three concentrations of red spinach extract (3%, 4%, and 5%) replicated three times at the UPTD Fish Breeding Center in North Binjai Regency, North Sumatra Province. Furthermore, red spinach extract was mixed with the commercial diet containing 41% crude protein and administered to fish at a rate of 3% of their body weight daily for 40 days. The results showed a significant effect of red spinach extract doses on guppy color brightness (P0.05), but no significant influence on weight gain and fish survival (P0.05). It was also discovered that the average color increase was 2,652 in feed mixed with 5% red spinach extract. Similarly, the highest fish weight gain was observed at the 5% concentration, which did not significantly differ from the other concentrations. Fish survival rates were high, with no significant differences among the treatments. Therefore, it was concluded that the optimal concentration of red spinach extract for enhancing guppy color brightness was 5%
Correlation and determination of the Metabolizable Energy (ME) of tropical forage with nutrient content for ruminants
Authors: Indah Andi Sukma , Permana Idat Galih , Despal Despal 
Published: July 2023

The metabolizable energy (ME) of tropical forages measured by in vivo method in ruminants had a high degree of accuracy but requires a long time and is expensive. One method that can be done is the ME estimation model. The objectives of the present study were carried out to investigate the relationship between tropical forage nutrient content and ME for ruminants as well as determine and validate a model for estimating ME of tropical forage based on nutrient content. A total of 26 forage samples consisting of 14 types of grass and 12 legumes were obtained after data pre-processing or data cleaning and data normalization. Forage samples will be grouped into 3, Grass + Legume (G+L=26), grass (R=14), and legume (L=12). The database used is Crude Protein (CP), Extract Ether (EE), Neutral Detergent Fiber (NDF), Acid Detergent Fiber (ADF), and hemicellulose as well as ME with in vivo experiments. The initial stage is preprocessing data. Nutrient content and ME were analyzed using Pearson Correlation and followed by multiple linear regression to determine the ME estimation model. However, validated used the mean absolute deviation (MAD), root means square error (RMSE), and mean absolute percentage error (MAPE). The results showed that there was a significant and highly significantly correlated between nutrient composition and ME in the Grass + Legume, Grass, and Legume groups so it could be used to determine ME. There are 9 regression equations with significance and have high R2 and after being validated with the lowest MAD, RMSE, and MAPE values, three regression equations are obtained with one each for each group Grass + Legume (G+L), Grass (R), and Legumes (L). It is concluded that the regression equation of ME of tropical forage is MER+L = 12.429 – 0.122 ADF for Grass + Legume, EMR = 15.609 – 0.115 NDF for Grass, and EML = 3.726 – 0.186 CP for Legume.
Length-weight relationships and condition index of Pokea clams (Batissa violacea var. celebensis, von Martens 1897) in the Laeya River, Southeast Sulawesi, Indonesia
Authors: Bahtiar Bahtiar , Findra Muhammad Nur , Ishak Ermayanti 
Published: July 2023

The length-weight relationship and condition index of pokea clams in the Laeya River are not fully known. This study was aimed to determine the length-weight relationship and condition index of pokea clams in the Laeya River, Southeast Sulawesi. This research was conducted 10 months from May 2016 to February 2017 in the Laeya River, Southeast Sulawesi. Pokea clams are collected using a shovel. The length and weight of each clam was using calipers and analytical scales with accuracy of 0.05 mm and 0.01 g, respectively. The weight of the shell and dried meat was obtained by drying the shells first using an oven and weighing using an analytical balance with an accuracy of 0.01 g and 0.0001 g, respectively. The results showed that the relationship between length and weight of pokea clams in males and females were 2.61 and 2.78, respectively; with R2 values of 0.89 and 0.93, respectively. The highest b values for males and females were found in July with values of 3.03 and 2.94, respectively. The lowest b value was found in November with values of 2.45 and 2.46, respectively. The condition index values for males and females were 4.7 ± 2.2 and 5.17 ± 2.32, respectively. The highest condition index was found in May with values of 6.00 ± 3.07 and 7.83 ± 2.55, respectively. The condition index values for males and females increased with increasing shell size. Male and female at the largest size (6.01-6.05 cm) had the highest index with values of 8.05 ± 6.41 and 9.12 ± 3.38, respectively. In conclusions, the growth was negative allometric pattern, condition index was in fat category, and had peak spawning in July and experienced partial spawning in September-February.