bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expression patterns of sex steroid receptors in developing mesonephros of the male mouse: three-dimensional analysis
Authors: Omotehara Takuya , Hess Rex A , Nakata Hiroki , Birch Lynn A , Prins Gail S , Itoh Masahiro 
Published: January 2023

AbstractThe androgen pathway via androgen receptor (AR) has received the most attention for development of male reproductive tracts. The estrogen pathway through estrogen receptor (ESR1) is also a major contributor to rete testis and efferent duct formation, but the role of progesterone via progesterone receptor (PGR) has largely been overlooked. Expression patterns of these receptors in the mesonephric tubules (MTs) and Wolffian duct (WD), which differentiate into the efferent ductules and epididymis, respectively, remain unclear because of the difficulty in distinguishing each region of the tracts. This study investigated AR, ESR1, and PGR expressions in the murine mesonephros using three-dimensional (3-D) reconstruction. The receptors were localized in serial paraffin sections of the mouse testis and mesonephros by immunohistochemistry on embryonic days (E) 12.5, 15.5, and 18.5. Specific regions of the developing MTs and WD were determined by 3-D reconstruction using Amira software. AR was found first at the distal end (gonadal side) of MTs at E12.5, and the epithelial expression showed increasing strength from cranial to the caudal side. Epithelial expression of ESR1 was found in the cranial WD and MTs near the WD first at E15.5. PGR was weakly positive only in the MTs and cranial WD starting on E15.5 but negative in the distal end of the MTs. This 3-D analysis suggests that gonadal androgen acts first on the distal end of MTs but that estrogen is the first to influence MTs on the WD side, while potential PGR activity is delayed and limited to the epithelium.
Are Exposure to Health Information and Media Health Literacy Associated with Fruit and Vegetable Consumption?
Authors: Jindarattanaporn Nongnuch , Rittirong Jongjit , Phulkerd Sirinya , Thapsuwan Sasinee , Thongchareonchupong Natjera 
Published: January 2023

Abstract
Background: Health information promotes a healthy lifestyle; however, media health literacy (MHL) is essential to personal intake, especially fruit and vegetables (F&V). This study aimed to determine how exposure to health information and MHL affect F&V consumption among Thai youth age 10-14 years. Health behavior at this age can be an important determinant of consumption habits when transitioning into adulthood.
Methods: A stratified two-stage sample survey was conducted to recruit 1,871 youth across regions to be nationally representative. Qualtrics offline survey application was used for data collection through face-to-face, personal interviews. Multiple regression was used to analyze the explanatory variables on F&V intake.
Results: This study found that almost 70% of Thai youth were exposed to health-related content via the Internet, and had low analytical skills to process that information. Grade Point Average (GPA), exposure to health information, various media types, frequency of exposure to health information, and MHL influenced the frequency of F&V intake. Health status related to fruit intake, age, place of residence, amount of pocket money, and body mass index (BMI) were associated with F&V consumption.
Conclusion: Exposure to health information and MHL are associated with F&V intake. Therefore, exposure to health information and MHL should be addressed for policy formulation in Thai schools and the health system.
Deep learning-based automated detection and multiclass classification of focal interictal epileptiform discharges in scalp electroencephalograms
Authors: Chung Yoon Gi , Lee Woo-Jin , Na Sung Min , Kim Hunmin , Hwang Hee , Yun Chang-Ho , Kim Ki Joong 
Published: January 2023

Abstract

Detection and spatial distribution analysis of interictal epileptiform discharges (IEDs) are important for diagnosing, classifying, and treating focal epilepsy. This study proposes deep learning-based models to detect focal IEDs in electroencephalography (EEG) recordings of the frontal, temporal, and occipital scalp regions. This study included 38 patients with frontal (n = 15), temporal (n = 13), or occipital (n = 10) IEDs and 232 controls without IEDs from a single tertiary center. All EEG recordings were segmented into 1.5-s epochs and fed into 1- or 2-dimensional convolutional neural networks to construct binary models to detect IEDs in each focal region and multiclass models to categorize IEDs into frontal, temporal, and occipital regions. The binary models exhibited accuracies of 79.3–86.4%, 93.3–94.2%, and 95.5–97.2% for frontal, temporal, and occipital IEDs, respectively. The three and four multiclass models exhibited an accuracy of 87.0–88.7% and 74.6–74.9%, respectively, with temporal, occipital, and non-IEDs F1-scores of 89.9–92.3%, 84.9–90.6%, and 84.3–86.0% and 86.6–86.7%, 86.8–87.2%, and 67.8–69.2% for the three- and four-class (frontal, 50.3–58.2%) models, respectively. The constructed deep learning-based models could help enhance EEG interpretation. Although they performed well, the resolution of region-specific focal IED misinterpretations and further model improvement are needed.
Diversity and structure of the understory of two forest ecotones in Maranhão and the influence of the urban environment
Authors: Santos Catherine Rios , Oda-Souza Melissa , Almeida Eduardo Bezerra , Zickel Carmen Sílvia 
Published: January 2023

Abstract

Forest ecotones are floristically rich but anthropogenic disturbances can differentiate their vegetation structure. This study evaluated the understory diversity of urban and nonurban forests in Maranhão. It tested the hypotheses that the understory of the nonurban forest has greater diversity and richness and that the spatial distribution of these variables in the understory of the urban forest has weak spatial dependence. The study was conducted in the municipalities of São Luís (urban area) and São José de Ribamar (nonurban area). Thirty plots (25m²) were demarcated and the woody individuals up to 2 m tall were measured. All phytosociological parameters were calculated. The differences in richness, density, and diversity were analyzed between the areas with the Mann-Whitney test, non-metric multidimensional scaling, and Hutcheson t-test. To visualize the variation in richness and diversity of the vegetation, ordinary kriging was used. There was a difference in the floristic composition and density of each species in the two areas; the richness and diversity were significantly greater in the nonurban area. The species with the highest IVs wereFaramea nitida,Myrcia amazonica,andEphedranthus pisocarpusin the nonurban forest andProtium heptaphyllum,Randia armata, andMoquilea tomentosain the urban forest. Both understories had high diversity compared to other Amazonian regions. However, weak spatial dependence was found in the urban area, suggesting high anthropogenic interference in the environment. It is noteworthy that the areas represent a parcel of original ecotone vegetation in Maranhão and effective actions are needed to restore and conserve its diversity.
Tautomeric Mixture Coordination Enables Efficient Lead-Free Perovskite LEDs
Authors: Wang Ning , Han Dongyuan , Wang Jie , Agosta Lorenzo , Zang Ziang , Zhao Bin , Kong Lingmei , Lu Haizhou , Mosquera-Lois Irea , Carnevali Virginia , Dong Jianchao , Zhou Jianheng , Ji Huiyu , Pfeifer Lukas , Zakeeruddin Shaik , Yang Yingguo , Wu Bo , Rothlisberger Ursula , Yang Xuyong , Graetzel Michael 
Published: January 2023

Abstract
Lead (Pb) halide perovskite light-emitting diodes (PeLEDs) have demonstrated extraordinary optoelectronic performance. However, the toxicity of Pb has raised as a serious concern. Removing Pb from the best-performing PeLEDs without compromising their excellent external quantum efficiencies (EQEs) remains a challenge. Here we report a tautomeric mixture coordination-induced electron localization strategy to fundamentally stabilize Pb-free TEA2SnI4 (TEAI, 2-thiophenethylammonium iodide) perovskite by incorporating cyanuric acid (CA). We demonstrate that a crucial function of the coordination is to amplify electronic effects and even extend to Sn atoms without strong bonding with CA, due to the formation of H-bonded tautomeric dimer and trimer superstructures on the perovskite surface. This electron localization weakens adverse effects from Anderson localization and contributes to more ordered and stable crystal structure in the resultant TEA2SnI4, which synergistically improve the perovskite with two orders of magnitude reduction in nonradiative recombination capture coefficient and about 2-fold enhancement in exciton binding energy. Levering by the interactional profit, our target Pb-free PeLED demonstrated an EQE of up to 20.13 per cent, representing a performance comparable to that of state-of-the-art Pb-containing PeLEDs. We anticipate that these findings will provide insights into the stabilization of Sn(II) perovskites and inspire researchers to pioneer Pb-free perovskite applications.
Risk Assessment of Particulate Matter (PM 2.5 and PM 10 ) During Winter Crop at the Agricultural Site of Delhi, India
Authors: Chaudhary Anita , Prakash Chandra , Sharma Sudhir Kumar , Mor Suman , Khaiwal Ravindra , Krishanan Pramila 
Published: January 2023

Abstract
In Indian cities, airborne particulate matter, PM2.5, is related with regional or across border problem and that of PM 10 with local-land urban problem. The present study was carried out for risk assessment of PM10 and PM2.5 and its associated carbonaceous component and heavy metals of an experimental agriculture farm site of Delhi, India. In our studies, at the agricultural site which is surrounded by heavy traffic and industries related sites, concentrations of both PM10 and PM2.5 varied significantly from 136.34 to 176.66 µg/m3 and 56 to 162 µ/m3 respectively. However, the concentrations of NOx were relatively higher during the months of February and March. The concentrations of O3 in the present study, were observed to be the highest in February. In general, the Hazard index for both adults and children population was reported to be < 1, which indicated the probability of non-carcinogenic risks to both populations as negative.
Wildflower habitats in turfgrass systems have variable effects on arthropod functional group abundance over multiple years
Authors: Hamon Laura , Kilpatrick Lauren , Billeisen Terri 
Published: January 2023

Abstract
Urbanization is rapidly influencing the abundance and diversity of arthropods. Within urban systems, managed turfgrass is a prominent cultivated crop which can support certain arthropod populations, but is inadequate for supporting many others. In an effort to mitigate the negative effects of turfgrass on arthropod biodiversity, increasing numbers of land managers are choosing to partially convert turf habitat to wildflower habitat using commercially-available seed mixes. However, the population dynamics of diverse arthropod groups in these systems is poorly known, with consequentially little information on best long-term practices for managing wildflower habitats in turfgrass systems. To address this gap, we sampled arthropods in turfgrass systems pre- and post-implementation of wildflower habitats and examined the change in abundance of multiple taxa and functional groups. Arthropod groups had diverse responses to wildflower habitat implementation, with bees having no significant changes in abundance, butterflies being most abundant one-year post-implementation, and predatory wasps and flies being relatively more abundant one- and two-year post-implementation. These results point to the need for more research on the long-term effects of wildflower habitats on beneficial insects in turfgrass habitats, and how to optimize management of both wildflower habitats and nearby turfgrass to support arthropod biodiversity.
Daratumumab monotherapy for refractory lupus nephritis
Authors: Roccatello Dario , Fenoglio Roberta , Caniggia Ilaria , Kamgaing Joelle , Naretto Carla , Cecchi Irene , Rubini Elena , Rossi Daniela , De Simone Emanuele , Vecchio Giulio Del , Cozzi Martina , Sciascia Savino 
Published: January 2023

Abstract
Refractory lupus nephritis (RLN) is a clinical condition with high risk of a poor outcome and often life-threatening. Six patients (one male and 5 females), aged 41.3 years (range 20 to 61 years) were treated with Daratumumab monotherapy, a monoclonal antibody targeting CD38 which is highly expressed on the surface of many immune cells, especially plasma cells. The treatment protocol consisted of 16 mg/kg daratumumab administered intravenously weekly for 8 weeks, then every two weeks 8 more times, and lastly monthly (maximum 8 infusions). All patients failed previous treatments with the Standard of Care (SOC) including mycophenolate mofetil (MMF), cyclophosphamide (CYC), azathioprine and rescue therapies including Rituximab (RTX), Ocrelizumab, Belimumab, and iv IgG. One out of six patients did not show clinical response after 6 months of therapy, and Daratumumab was discontinued. Five patients showing a clinical response over the same period continued to be treated and reached a 12-month observation. Renal biopsy performed before daratumumab administration revealed a class IV LN in 1 patient, class V LN in 1 patient, class III + V LN in 1 patient and class IV + V LN in the other 2. Three patients achieved a complete renal response and the other two a partial renal response. A significant decrease in proteinuria from 5.6 gr/24 hours to 0.8 g/24 hours (p = 0.001) was achieved at 12 months. The mean value of serum Creatinine (sCr) decreased from 2.3 to 1.5 mg/dl. Improvement of clinical symptoms was paralleled by seroconversion of anti-double-stranded DNA antibodies (p = 0.03), significant decrease in interferon-gamma values (p = 0.0006), BMCA-B-cell maturation antigen (p = 0.0005) and soluble CD163 levels (p = 0.045), and increase in C4 (p = 0.018) and IL 10 levels (p = 0.0006). Clinical remission was substantiated by improvement of SLEDAI-2K score (p = 0.03). Daratumumab was generally well tolerated. These data suggest that Daratumumab administered alone (i.e., without any other immunosuppressant or agents targeting B-cell activating factor) is highly effective in RLN.
Equivalence of Sobolev norms with respect to weighted Gaussian measures
Authors: Davide Addona 
Published: January 2023

Abstract

We consider the spaces Lp(X, ν; V), where X is a separable Banach space, μ is a centred non-degenerate Gaussian measure, ν := Ke−U μ with normalizing factor K and V is a separable Hilbert space. In this paper we prove a vector-valued Poincaré inequality for functions F ∈ W 1,p(X, ν; V), which allows us to show that for every p ∈ (1,+∞) and every k ∈ N the norm in W k,p(X, ν) is equivalent to the graph norm of DkH (the k-th Malliavin derivative) in Lp(X, ν). To conclude, we show exponential decay estimates for (TV (t))t≥0 as t → +∞. Useful tools are the study of the asymptotic behaviour of the scalar perturbed Ornstein-Uhlenbeck (T(t))t≥0, and pointwise estimates for |DHT(t)f |pH by means both of T(t)|DHf |pH and of T(t)|f |p.
SubjClass[2010]: 28C20; 46E35; 47D06
Impact of climate change on the distribution and habitat suitability of the world’s main commercial squids
Authors: Guerreiro Miguel , Borges Francisco , Santos Catarina , Xavier José Carlos , Hoving Henk-Jan , Rosa Rui 
Published: January 2023

Abstract
Climate change is expected to produce major effects across marine life, and cephalopods seem to benefit from these effects. Of these animals, squids exhibit the greatest levels of biomass and of a substantial importance for human consumption. To test the hypothesis that effects of climate change are beneficial for commercial squid, we used species distribution models on climate scenarios for the period between 2000 and 2014, as well as the years 2050 and 2100 (RCP [representative concentration pathway] 2.6, 4.5, 6.0, and 8.5; CMIP5). Our results suggest that consequences of climate change scenarios are species specific. In the North Pacific and Northwest Atlantic, habitat suitability may increase (from + 0.83% [Doryteuthis pealeii] to + 8.77% increase [Illex illecebrosus]), while the habitat of other species is predicted to decrease (from − 1.03% [Doryteuthis opalescens] to -15.04% decrease [Loligo reynaudii]). Increases in habitat suitability occurred mostly at higher latitudes, while suitable habitat decrease was predicted for the tropical regions. Stronger changes were attained with the harsher emission scenarios. In the future, as a result of warming of the Arctic, squid habitat may increase along both coasts of North America. In the Southern Hemisphere, squids may lose habitat with no poleward habitat alternatives to move into. Contrary to our hypothesis, commercial squid do not stand to benefit from climate change. Since these squid are an important food source for marine megafauna and humans, it is imperative that climate change biogeographic impacts are considered for a sustainable management of this important group of molluscs.
Copper Removal from Aqueous Solution by Polymer-Enhanced Ultrafiltration Method Using Polyacrylic Acid (PAA) and Polyvinyl Alcohol (PVA) Polymers
Authors: Mamaghani Ashkan Gorgani , Bidhendi Gholam Reza Nabi , Mehrdadi Naser 
Published: January 2023

Abstract
The presence of heavy metals with low concentrations in water sources can cause problems for human beings, the environment, and animals; so heavy metals should be eliminated from different wastewaters before discharging into water sources. Copper is one of the heavy metals which can cause several problems in low concentrations for animals and especially problems for plants. There are different methods for copper removal from aqueous solutions such as adsorption, chemical precipitation, photocatalysis, ion exchange, membrane filtration, etc. Ultrafiltration (UF) is a kind of membrane filtration. Polymer-enhanced ultrafiltration (PEUF) is able to overcome the limitation of removing heavy metals in UFs and achieve a high removal of heavy metals. In this research, polyacrylic acid (PAA) and polyvinyl alcohol (PVA) polymers, were used separately with UF to remove copper (Cu) from aqueous solutions. Effects of parameters such as pH, copper concentration, the weight ratio of polymer to copper (P/Cu), ionic strength of the influent solution, and filtration pressure on PEUF performance were examined. Also, response surface analyses were applied to see the simultaneous effect of two parameters. Copper removal of more than 67% was obtained by the use of a 5 kiloDalton (kDa) UF membrane without using a polymer which is a relatively high amount. In some conditions, the study has achieved more than 90% copper removal.
Corporate board attributes, institutional strength and energy disclosure practices for controlling greenhouse gas emission in Nigeria
Authors: Jibril Rabiu Saminu , Isa Muhammad Aminu , Hamid Kabir Tahir , Maigoshi Zaharaddeen Salisu 
Published: January 2023

Abstract

The use of non-renewable energy by firms in Nigeria seriously affects biodiversity and the general well-being of the populace. The consequences led the country to be among the top pollution producers globally. However, Nigeria was among the parties that unanimously agreed on the Glasgow Climate Change Conference 2021, under the United Nations Framework Convention on Climate, to tackle greenhouse gas emissions resulting from non-renewable energy sources. The study is a pioneer in examining how board attributes influence quality and quantity disclosure of energy consumed by the listed non-financial firms for the period of 5 years (2016 – 2020). The study aims at providing empirical evidence on how institutional strength influences the relationship between board attributes and firms' energy in reducing emission discharges and achieving sustainable development goals on world climate policy. The study obtained data from a sample of 78 listed non-financial firms, content analysis technique was employed to compute energy disclosure indexes using Global Reporting Initiatives standards. The study runs a generalized method of movement (GMM) to regulate the impending endogeneity of the selected listed companies in Nigeria. The study also conducted several to robust the findings. The overall results found that board independence, meeting, gender and ownership were significantly related to energy disclosure. The study found an insignificant association between ownership and energy disclosure. Institutional strength has not influenced the relationship between independence, meetings, size and gender on energy disclosure. Institutional strength has positively influenced the relationship between ownership and energy disclosure. Thus, the United Nation should set up a strong committee to evaluate the effectiveness and weaknesses of Global Reporting Initiatives standards as the most widely used Environmental, Social and Governance globally. This will expose the peculiarities of most developing nations like Nigeria in adopting the standards and way forwards to attain Sustainable Development Goals 13.
Applied Research of comprehensive advance geological prediction in Daluoshan diversion tunnel
Authors: Liu Mingqing , Gan Qinyu 
Published: January 2023

Abstract
In order to study the accuracy of the comprehensive advance geological prediction method in the prediction of geological conditions in the tunnel construction project, based on the Daluoshan Diversion Tunnel Project in Wenzhou, Zhejiang Province, this paper selects typical sections of the diversion tunnel, uses the tunnel seismic scattering imaging technology TST and geological radar to transmit seismic and electromagnetic signals to the face detection section, and processes and interprets the collected signal information. The verification is carried out by using advanced blasthole and advanced drilling. The results show that the geological prediction results are relatively consistent with the actual exposure, and the advance geological prediction can give play to the advantages of various technologies and verify each other, which can greatly improve the accuracy of the advance geological prediction in the application of the headrace tunnel, and provide reference and basis for the later construction, and provide safety assurance.
Work Stressors and Intention to Leave Among Jordanian Nurses During COVID-19: A Cross-sectional study
Authors: Omoush Ola A. , Abushosha Ghada M. , Oweidat Islam A. , Nashwan Abdulqadir J. 
Published: January 2023

Abstract

Background: Nurses come across several stressors in the workplace, especially during COVID-19 outbreaks. Work stressors are associated with physical and psychological health problems among workers and thus increase their intentions to leave work. Aim: This study aimed to identify Jordanian nurses’ perceptions regarding work stressors and intention to leave levels, examine if nurses' perceptions regarding work stressors and intention to leave scores differ across nurses' demographic data, and investigate the relationship between work stressors and intention to leave.
Methods: A descriptive cross-sectional study was conducted. A convenient sample of 154 nurses who worked with COVID-19 patients participated in this study. Self-reported questionnaires were sent online via social media applications to participants.
Results: Most of the participants (85.7%) had a positive level of work stressors regarding their perceptions. Concerning the intention to leave, 57.8% of participants had a slightly positive level, and 21.4% had a moderately positive level. There were significant differences in work stressors and the intention to leave scores according to nurses' age, marital status, educational level, and experience duration (p< 0.015). Also, work stressors significantly correlated with intention to leave (r = 0.52, p< 0.001).
Conclusions: Health organizations must adopt strategies, programs, and policies to reduce work stressors and the intention to leave among nurses during these stressful events.