bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a novel nomogram to predict severe adenovirus pneumonia in children with adenovirus pneumonia
Authors: fang yulian , Liu Guangping , Li Xiaoying , Hou Mengzhu , Wang Lu , Wang Ning , Guo Zhiyong , Ning Jing 
Published: May 2023

Abstract
Background Severe adenovirus pneumonia (SAP) in children is characterized by multiple complications in the respiratory system, a high mortality rate, and a long recovery period. The study aimed to develop and validate a nomogram for predicting SAP in patients with adenovirus pneumonia (ADVP).Methods In this study, a total of 202 children with ADVP were collected between January 2019 and December 2020. Demographic and clinical characteristics of patients who participated in this study were utilized to develop a nomogram for predicting SAP. The data were categorized as training and validation datasets using random split sampling (split ratio = 7:3). Univariate logistic regression was used to select predictors. Multivariate logistic regression analysis was applied to construct a predictive model by introducing the predictors. The nomogram was visually developed on the basis of the selected predictors. The discriminatory ability of the model was determined using the receiver operating characteristic curve. Moreover, the prediction accuracy was evaluated using a calibration curve, and clinical effectiveness was evaluated by decision curve analysis (DCA).Results Univariate and multivariate logistic regression demonstrated that the duration of fever (OR: 1.500, 95% Cl: 1.261–1.783), atelectasis (OR: 12.581, 95% Cl: 1.323–119.615), L% (OR: 0.938, 95% Cl: 0.905–0.972), and FER (OR: 1.006, 95% Cl: 1.002–1.010) were independent predictors of SAP in patients with ADVP. The nomogram exhibited good discrimination with area under the curve (AUC) in the training dataset (0.860, 95%Cl: 0.800–0.920) and validation dataset (0.818, 95% Cl: 0.690–0.947). Through the calibration plot and Hosmer–Lemeshow test, the predicted probability was consistent with the actual probability in the training dataset (P = 0.545) and validation dataset (P = 0.545), and DCA showed good clinical utility.Conclusions In this study, a nomogram for predicting SAP among ADVP was developed and validated. It also showed good performance, indicating its discrimination ability, calibration ability, and clinical value. Thus, it may be used for the early identification of SAP, which will help physicians take timely intervention and appropriate management.
Creatine and Its Relationship With Methionine + Cysteine in Finishing Pig Diets
Authors: Pozza Paulo Cesar , Sitanaka Natália Yoko , Gasparino Eliane , Esteves Lucas Antonio Costa , de Souza Mariana Cardoso , Pozza Magali Soares Santos , Nunes Ricardo Vianna , Murakami Alice Eiko 
Published: May 2023

Abstract
This study aimed to evaluate the interaction between creatine monohydrate (CMH) and standardized ileal digestible (SID) methionine + cysteine (Met+Cys) in finishing pig diets on the performance, carcass traits, pork quality, blood biochemistry, gene expression of creatine transporter and muscle antioxidant action. Forty gilts, averaging 75.26±0.87 kg of initial weight, were distributed in a randomized blocks design, arranged in a 2 x 2 factorial scheme, consisting of two dietary CMH supplementation (0 and 0.10%) and two SID Met+Cys levels (0.40 and 0.44%), with 10 replicates and one animal per experimental unit. There was no interaction between CMH and SID Met+Cys on the performance and SLC6A8 gene expression (P&gt;0.05). However, interactions were observed for the backfat thickness at P3 (P=0.004), drip water loss (DL) (P=0.018), thawing water loss (TL) (P=0.042) and plasma creatinine concentration (P=0.03). Supplementation with CMH provided low fat deposition at P3 point. Diets with the lowest SID Met+Cys level (0.40%) and containing CMH (0.10%) presented the highest water losses (DL and TL). Plasma creatinine concentration was lower in pigs receiving diets with 0.10% CMH than those not receiving, but only in diets containing 0.44% SID Met+Cys. In addition, 0.44% SID Met+Cys increased the percentage of inhibition of the DPPH radical (P=0.022). The effects of supplementing 0.10% CMH in finishing pig diets are evident on pork quality by using adequate levels of SID Met+Cys, which also assist in preventing the oxidative lipid damage in the Longissimus dorsi muscle.
Changes in soil properties and quantitative and qualitative yield of peppermint (Mentha piperita L.) in response to nitrogen fertilizers (organic and chemical) under Water-Deficit Conditions
Authors: Bghbani-arani Abolfazl , Poureisa Mona 
Published: May 2023

Abstract
Drought and lack of nutrients (including nitrogen) limit crop production in arid and semi-arid regions, including Iran. In order to investigate the combined effect of nitrogen fertilizer sources (organic and chemical) under low water stress on soil properties, biological yield and peppermint essential oil, a three-year experiment in the years (2017–2019) was performed in the semi-arid region of Iran. The experiment was conducted as split plots in the form of randomized complete blocks with three replications. Experimental treatments include three irrigation regimes (irrigation at field capacity and after draining 25, 40 and 55% of usable water in the root zone) as the main factor and six fertilizer treatments based on plant nitrogen requirements (100% fertilizer, respectively). Chemical, without fertilizer, 50% chemical fertilizer + 50% azocompost, 100% vermicompost, 100% azocompost and 50% chemical fertilizer + 50% vermicompost) as sub-factors. The results showed that water-deficit conditions decreased organic carbon, total nitrogen content, soil phosphorus and potassium and biological yield and increased the percentage of peppermint essential oil. Also, in most of the treatment compositions of irrigation regime, the application of organic fertilizer (especially pure vermicompost and azocompost treatments) or combination with chemical fertilizer the increase organic carbon, macronutrients (nitrogen and phosphorus) and micro (iron and zinc) in soil solution, causing improved biological yield and essential oil content and moderated the effects of water-deficit stress on peppermint. In general, in water-deficit conditions such as Iran and the direction of sustainable agriculture and healthy medicine production, if the purpose of planting this plant is qualitative yield (percentage of essential oil) can be applied by applying severe water deficit and application vermicompost with the highest percentage of essential oil production, more Saves 50% on water consumption.
Effects of adjacent periodontitis on osseointegrated dental implants
Authors: Ryoo Keun-Soo , Kim Kyung-Hwa , Cho Young-Dan , Seol Yang-Jo , Ku Young 
Published: May 2023

Abstract
This study aimed to investigate whether newly emerged periodontitis or apical periodontitis on the adjacent teeth affects osseointegrated dental implants in a beagle dog model. The mandibular second and fourth premolars on both sides of three beagles were extracted. Two months after extraction, four bone-level implant fixtures, two on both sides of each mandible, were placed in each beagle. Six weeks after implant surgery, healing abutments were connected. After sufficient osseointegration, plaque control was performed in the control group, while periodontitis and apical periodontitis were induced in the experimental groups. The beagles were euthanized for histological analyses five months after induction of experimental periodontitis. The implants in the control and apical periodontitis groups were well-maintained, while those in the periodontitis group showed clinical signs of inflammation with bone resorption. The bone-to-implant contact (BIC) and bone area (BA) values in the periodontitis group were lower than those in the other groups. The distance between the implant shoulder and the first BIC was significantly greater in the periodontitis group than in the control group. Unlike apical periodontitis, periodontitis of the teeth surrounding dental implants can induce peri-implantitis. Periodontal healthcare is essential for long-term dental implant survival.
Prevalence and Associated Factors of Hearing impairment among Children attending Birhanzare Primary School, Addis Ababa, Ethiopia
Authors: Haile Bitseat W. , Feyissa Yibeltal M. , Kassa Betelehem B , Etissa Eyob Kebede , Asrat Haregewoin , Tadesse Mikael A. , Mekasha Amha 
Published: May 2023

Abstract
Background Hearing impairment is the most prevalent sensory disability globally and a condition of growing concern with around 5.3% of the population having disabling hearing loss. It has significant impacts on the individual and society. The problem is even greater for children as hearing is the main source for language, speech, and cognitive developments.Methods A school based cross-sectional study at an elementary school in Addis Ababa, Ethiopia was conducted in May 2018. One hundred and ten students from grades 1–5 were enrolled in the study. A structured questionnaire filled by parents/caregivers. Audiometric testing and otoscopic examinations were used to determine hearing impairment and abnormal otoscopic findings respectively. Data was analyzed using SPSS version 25. Descriptive and basic statistical analysis was applied. Logistic regression was used to identify risk factors for hearing impairment. Statistical significance was declared at p values < 0.05.Results A total of 106 students (27.4% male and 72.6% female) were enrolled in the study. Abnormal otoscopic findings were observed among 30.2% of the participants, with wax being the commonest abnormality observed in twenty-two point eight (22.8%), pus discharge and dull tympanic membrane in 4%, foreign bodies were found in 3 of the participating students (2.8%). The prevalence of disabling hearing impairment in this study (> 25dB on the better hearing ear), was 34% where the majority (32.1%) had mild hearing impairment. Abnormal otoscopic finding showed significant association with hearing impairment.Conclusion The prevalence of hearing impairment in our study is higher than WHO and other regional estimates. Given the high prevalence of HI, availability of management options for mild HI, and its underlying causes, early hearing screening programs in children should be integrated into existing systems such as the Ethiopian school health program as well as early childhood growth and development monitoring entry points.
Experiences of women with psychological suffering in the puerperium: interpretations and meanings
Authors: Mapelli Lina Domênica , Gozzo Thais de Oliveira 
Published: May 2023

Abstract
Background: Women in Brazil are guaranteed the right to a puerperal consultation until the 42nd day of the puerperium. It has been observed that they only attend the health services for childcare consultations, and the care provided is solely focused on the newborns. This approach culminates in dissatisfaction, inadequate guidance, and unresolved care to puerperal health.
Methods: A qualitative research was conducted on 27 puerperae from São Paulo, guided by the compass of the theoretical framework of symbolic interactionism and processed by the methodological framework of narrative analysis.
Results: I. Disenchantments in the puerperium: groping the puerperium in concreteness; inexorable fatigue in the praxis of maternity; devotion to the care of the newborn; unpleasant bodily changes in the puerperium and fragile self-care; II. Via crucis of breastfeeding; III. Restlessness in the puerperium; IV. Nuances of psychological suffering in the puerperium.
Conclusions:When entering the world of the puerperium, the difficulties encountered with the care of the newborn and breastfeeding point to the woman's susceptibility to puerperal blues, fatigue, anxiety, and puerperal depression. Moreover, other sufferings such as non-suicidal self-injury, periodic binge eating disorder, and puerperal obsessive-compulsive disorder may also occur. Nonetheless, professionals should be prepared for the detection, treatment, and follow-up of psychological depression in the puerperium.
Professional happiness assessment tool for nurses：A scoping review
Authors: Yang Lijun , Fan Songsong , Li Qi , Ma Hongwen 
Published: May 2023

Abstract
Background: With the continuous development of positive psychology, happiness at work has become a new topic, especially in nurses. However, there is a lack of scope review that can summarize the assessment tools of nurses' occupational happiness.
Objective: This study systematically searched the evaluation tools of nurses' occupational happiness, and analyzed the basic characteristics, dimensions, reliability , validity and localization of assessment tools. To provide reference for effective assessment of nurses' occupational happiness in the future.
Methods: A scoping review was conducted using search results from four bibliographic databases.
Results: A total of 3912 articles were retrieved, 33 articles were included. 3797 articles were retained after duplicate articles were eliminated. In the title and abstract screening, 3662 articles were excluded. The full text selection eliminated 102 articles. In the end, 33 articles from 20 countries were left on the scope review. Among them, 17 were universal assessment tools and 3 were dedicated to nurses. The content of evaluation often involves individual positive emotion, negative emotion and life satisfaction. The universal tool is mainly used to evaluate the subjective well-being of individual population and is widely used. Assessment tools for the nurse population include not only the assessment range of universal tools, but also the assessment of happiness in the nurse's work environment. The scoring method is mainly Likert scoring. All 20 tools have been introduced and localized in different countries and tested for reliability and validity in nurses.
Conclusions: The improvement of nurses' occupational happiness will mean higher quality of care and general improvement of individual health. Evaluating nurses' occupational happiness is the premise of improving nurses' occupational happiness. There is still a lack of convenient and accurate assessment tools in clinical practice. In the future, researchers should identify the differences in nurses' occupational happiness studies in different countries, apply the definition of norms, and develop assessment tools for nurses' occupational happiness in different departments. In the test of reliability and validity, the sample size should be expanded and the multi-center test should be carried out to enhance the evaluation tool persuasion, improve the quality of assessment tools and expand the degree of popularization. In clinical practice, assessment tools are standardized step by step.
Habitat, plant height, and soil nutrients are important determinants of the Hypericum perforatum microbiome
Authors: Petipas Renee , Higgins Steven A. , Koechli Chantal , Debenport Spencer J. , Jack Chandra N. , Geber Monica A. , Buckley Daniel H. 
Published: May 2023

Abstract
Aims Saint John’s wort, Hypericum perforatum, is a medicinally and ecologically important perennial plant species that has a broad global distribution. Despite the species’ importance, little is known about the factors that structure its microbial communities and the identity of microbes that enhance plant growth and fitness. Here we aim to describe the microbial communities associated with Hypericum perforatum and elucidate factors that structure these communities.Methods We collected H. perforatum root samples in three adjacent habitat types: wet and dry alvars (two types of limestone barren) and fallow agricultural fields (i.e. old-fields), in Jefferson County, New York. We used high-throughput amplicon sequencing of the SSU-rRNA gene (16S, bacteria) and the internal transcribed spacer region 1 (ITS1, fungi) to characterize the root microbiome of H. perforatum. At each root sampling location, we quantified aspects of the plant phenotype and soil characteristics to evaluate habitat variables that correlate with root microbial communities.Results Alvars had ~ 13% higher bacterial richness compared to old-fields. In contrast, old-fields had 28% higher fungal richness than dry alvars, but similar fungal richness to wet alvars. Habitat and plant height were important predictors of microbial community composition. We identified two bacterial taxa positively associated with plant height, both belonging to the bacterial phylum Actinobacteria.Conclusions This work contributes to our understanding of the environmental determinants of microbial community composition. Additionally, we were able to identify bacterial taxa that are correlated with plant health and should be investigated further as indicators of soil health or plant-growth promoting rhizobacteria.
Clinical analysis of balanced chromosomal translocation with primary infertility in couples
Authors: Wang Kangying , Lin Hua , Wu Fan , Liu Ben , Lun Yongzhi 
Published: May 2023

Abstract
Background:Two chromosomes undergo a break and exchange with each other, then the formation of two new derived chromosomes without a mitotic break is a reciprocal translocation. Reciprocal translocations are relatively common structural aberrations that can occur on any chromosome. Reciprocal translocations are called balanced translocations when there is only a change in position and no visible gain or loss of chromosome segments. Chromosomal translocations are rearrangements based on chromosomal breaks resulting in abnormal chromosome structure and are an important cause of habitual abortion and fetal malformations[1].
Method: The karyotypes of patients were analyzed by collecting peripheral blood for lymphocyte culture, chromosome harvesting, filming, and G dominant band staining.
Result: The chromosomal results of the couples were 46, XY,t(13;16)(q34;q12.1) and 46, X,t(X;3)(p22.1;q26.2). They are both chromosomally balanced translocation carriers, with translocations occurring on chromosomes 13, 16, X, and 3. Their chromosome breakpoints are q34, q12.1, p22.1, and q26.2.
Conclusion: It is clinically rare for couples to be both chromosomal translocation carriers simultaneously. Abnormal chromosome structure is one of the leading causes of primary infertility in males or females[2]. Preimplantation genetic testing (PGT) allows genetic testing of gametes or embryos of chromosomal translocation carriers and selection of healthy or translocated embryos for transfer to solve the fertility problems faced by chromosomal translocation carriers.
Profiling risk factors for separation of infection complications in patients with gastrointestinal and nodal diffuse large B-cell lymphoma
Authors: Xue Min , Gao Zhenzhen , Yan Miaolong , Bao Yi 
Published: May 2023

Abstract
Objective:
To identify risk factors for infection complications in patients with gastrointestinal diffuse large B-cell lymphoma (GI-DLBCL) and nodal DLBCL (N-DLBCL) during treatment, respectively.
Methods:
Total 51 GI-DLBCL patients and 80 N-DLBCL patients were included after retrieving clinical data from a single medical center in the past ten years. Logistic regression analysis was utilized to analyze patients’ data, including baseline demographics, treatments and laboratory values, to determine independent risk factors of infection.
Results:
28 of 51 patients (54.9%) in the GI-DLBCL group and 52 of 80 patients (65%) in the N-DLBCL group were observed infection events during treatment. A multivariate logistic regression model revealed that Ann-arbor stage IV (P=0.046; OR: 22.867; 95%CI: 1.053-496.508) and high serum lactic dehydrogenase (LDH) at the time of diagnosis (LDH >252U/L; P= 0.036; OR: 1.110; 95%CI: 1.105-21.456) were independent risk factors for the development of infection in patients with GI-DLBCL after systemic treatment. In the N-DLBCL group, low hemoglobin (Hb) (P= 0.037; OR: 0.970; 95%CI: 0.943-0.998) at the time of diagnosis, high serum C-reactive protein (CRP) (P= 0.046; OR: 4.869; 95%CI: 1.020-1.209) and low platelet (P= 0.016; OR: 0.991; 95%CI: 0.982-1.000) at pre-infected laboratory examination were significant factors in the infection events during treatment.
Conclusions:
Discordant impendent risk factors induced infection may be present during the treatment in patients of GI-DLBCL and N-DLBCL. Close monitoring these risk factors is likely an effective strategy to prevent microbial infections in these patients.
Prediction of earthquake magnitude and seismic vulnerability mapping using artificial intelligence techniques: a case study of Turkey
Authors: Biswas Saptadeep , KUMAR DHRUV , Bera Uttam Kumar 
Published: May 2023

Abstract
Earthquake threats can result in fatalities, property destruction, and other cascading effects. Since it is nearly impossible to prevent earthquakes, anticipating the location of future earthquakes and figuring out their likelihood could be very helpful in reducing the seismic threat. In this work, seismic hazard prediction is executed to forecast adverse results using a range of potential artificial intelligence (AI) techniques, including ML and ANN. In the case study, we have looked at Turkey, which was recently and badly damaged by two earthquakes in February 2023. To predict earthquake magnitude, this study used a variety of regression algorithms, including Decision Tree Regressor, Extra-Trees Regressor, Random
Forest Regressor, Bayesian Ridge Regressor, and advanced gradient boosting decision tree (GBDT) algorithms such as XGBoost, LightGBM, and CatBoost, as well as three artificial neural networks (ANN). The predicted magnitude and risk zone of an earthquake are mapped using a geographic information system (GIS), and the maps performed well in terms of prediction. The generated maps is showing the expected earthquake risk based on historical data using the statistical computations. The ANN models perform exceptionally well, with R2 scores of 0.99 and 0.98 for training and case study data, respectively, and low values for MSE, MAE, and RMSE. ML models have demonstrated an exceptional ability to properly generalize from a single dataset, which implies they can accurately anticipates results for new and untested data.
The results would be helpful to many local emergency preparedness and infrastructure planning organizations.
Effects of diel oxygen cycling and benthic macrofauna on sediment oxygen demand
Authors: Gadeken Kara , Dorgan Kelly 
Published: May 2023

Abstract

Shallow marine soft sediments serve an important function by remineralizing organic matter, which consumes dissolved oxygen in the process. Sediment oxygen demand (SOD) depends on overlying water oxygen concentration but can also be altered by mixing and irrigating activities of sediment macroinfauna. Oxygen patterns in shallow coastal waters can vary substantially on short time scales, frequently following a diel cycle. However, little is known about whether and how the presence of macrofauna in sediment may affect SOD throughout a diel cycle. In this field study, we examined how sediment oxygen demand varied over a diel oxygen cycle and with sediment macroinfaunal presence. In situ flow-through benthic metabolism chambers were used to measure SOD at a high temporal resolution in discrete sediment patches. We found that sediments with more macroinfauna had greater average SOD over the diel cycle, consistent with previous studies. There was an interaction between the effects of faunal biomass and DO on SOD, suggesting that where macroinfauna are present they drive greater SOD during nightly low oxygen, presumably by enhancing their irrigation. SOD was also highly variable on a sub-diel timescale, and more variable in sediments with more macroinfauna. This indicates that sediment oxygen demand is dynamic and highly sensitive both temporally, on very short timescales, and spatially, in terms of resident fauna. High temporal and spatial resolution measurements, particularly on the diel scale, are critical to accurately estimate sediment metabolism.