bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dead but functional liquid nitrogen‐treated umbilical cord mesenchymal stem cells accelerate full‐thickness skin wound healing
Authors: Yang Yan , Feng Yuqing , Hu Meirong , Deng Jingxian , Wei Siying , Wang Zhaoyang , Li Lu , Huang Rufei , Wang Yuxin , Liu Yuan , Ye Tao , Huang Yadong 
Published: July 2023

AbstractBackgroundThe direct application of umbilical cord‐derived mesenchymal stem cells (UCMSCs) for promoting skin wound healing and regeneration is challenging due to strict maintenance requirements and unpredictable differentiation results.MethodsWe developed dead but functional liquid nitrogen‐treated UCMSCs (LNT‐MSCs) by rapidly immersing live UCMSCs (live‐MSCs) in liquid nitrogen.ResultsThe LNT‐MSCs maintained similar cellular structures and surface markers to those of live‐MSCs. We evaluated the therapeutic effects of both live‐MSCs and LNT‐MSCs on full‐thickness skin wound healing in rats. Our results showed that the LNT‐MSCs accelerated wound closure by enhancing the proliferation and migration of skin cells, promoting angiogenesis, and inducing a favourable macrophage phenotype shift. The regenerative healing effect of LNT‐MSCs was comparable to that of live‐MSCs, making them a potential alternative strategy for accelerating wound closure that avoids unpredictable differentiation results and creates a ready‐to‐use cell bank for clinical applications.
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand
Authors: Ou Feiya , Ferris Stephen T. , Kim Sunkyung , Wu Renee , Anderson David A. , Liu Tian‐Tian , Jo Suin , Chen Michael Y. , Gillanders William E. , Murphy Theresa L. , Murphy Kenneth M. 
Published: July 2023

AbstractIn vitro culture of bone marrow (BM) with Fms‐like tyrosine kinase 3 ligand (Flt3L) is widely used to study development and function of type 1 conventional dendritic cells (cDC1). Hematopoietic stem cells (HSCs) and many progenitor populations that possess cDC1 potential in vivo do not express Flt3 and thus may not contribute to Flt3L‐mediated cDC1 production in vitro. Here, we present a KitL/Flt3L protocol that recruits such HSCs and progenitors into the production of cDC1. Kit ligand (KitL) is used to expand HSCs and early progenitors lacking Flt3 expression into later stage where Flt3 is expressed. Following this initial KitL phase, a second Flt3L phase is used to support the final production of DCs. With this two‐stage culture, we achieved approximately tenfold increased production of both cDC1 and cDC2 compared to Flt3L culture. cDC1 derived from this culture are similar to in vivo cDC1 in their dependence on IRF8, ability to produce IL‐12, and induction of tumor regression in cDC1‐deficient tumor‐bearing mice. This KitL/Flt3L system for cDC1 production will be useful in further analysis of cDC1 that rely on in vitro generation from BM.
Methods for Preparing Hierarchical Zeolites by Chemical Etching and Their Catalytic Applications: A Review
Authors: Tan Lei , Jiao Nianming , Bai Xinrui , Wang Hongyan , Wang Jun , Wang Hui , Zhang Xiangping 
Published: July 2023

AbstractZeolites are widely used in petrochemical processes and refineries due to their well‐ordered microporous network and large surface area. However, the diffusion of reactants and products is hampered by the narrow microporous channels, causing limitations. To overcome this challenge, modifying the pore structure is crucial, and the chemical etching technique is a powerful tool that introduces mesopores and macropores, consequently enhancing mass transfer and accessibility. Diverse chemical etching methods have been invented, including exposure to both acids (organic/inorganic acids), alkali (organic/inorganic alkali), and neutral etchants (e. g., ammonium fluoride). This review summarizes and assesses the chemical etching methods and their relevance to catalytic cracking reactions, methanol to hydrocarbons (MTH), and biomass conversion. The potential of zeolites with modified pore structures has motivated researchers to develop novel methods to tackle the practical challenges associated with their applications.
Approximating grouped fixed effects estimation via fuzzy clustering regression
Authors: Lewis Daniel J. , Melcangi Davide , Pilossoph Laura , Toner‐Rodgers Aidan 
Published: July 2023

SummaryWe propose a new, computationally efficient way to approximate the “grouped fixed effects” (GFE) estimator of Bonhomme and Manresa (2015), which estimates grouped patterns of unobserved heterogeneity. To do so, we generalize the fuzzy C‐means objective to regression settings. As the clustering exponent
approaches 1, the fuzzy clustering objective converges to the GFE objective, which we recast as a standard generalized method of moments problem. We replicate the empirical results of Bonhomme and Manresa (2015) and show that our estimator delivers almost identical estimates. In simulations, we show that our approach offers improvements in terms of bias, classification accuracy, and computational speed.
Cycles of quadratic Latin squares and antiperfect 1‐factorisations
Authors: Allsop Jack 
Published: July 2023

AbstractA Latin square of order is an matrix of symbols, such that each symbol occurs exactly once in each row and column. For an odd prime power let denote the finite field of order . A quadratic Latin square is a Latin square defined byfor some such that and are quadratic residues in . Quadratic Latin squares have previously been used to construct perfect 1‐factorisations, mutually orthogonal Latin squares and atomic Latin squares. We first characterise quadratic Latin squares which are devoid of Latin subsquares. Let be a graph and a 1‐factorisation of . If the union of every pair of 1‐factors in induces a Hamiltonian cycle in then is called perfect, and if there is no pair of 1‐factors in which induce a Hamiltonian cycle in then is called antiperfect. We use quadratic Latin squares to construct new examples of antiperfect 1‐factorisations of complete graphs and complete bipartite graphs. We also demonstrate that for each odd prime , there are only finitely many orders , which are powers of , such that quadratic Latin squares of order could be used to construct perfect 1‐factorisations of complete graphs or complete bipartite graphs.
A general palladium‐catalyzed carbonylation synthesis of aurones with aryl bromides using CO2
Authors: Huang Zijun , Zhou Jiaxin , Dong Junyong , Liu Pengtao , Kuang Lei , Fang Zhengjun 
Published: July 2023

AbstractA general and efficient strategy synthesis of aurones by carbonylation reaction of aryl bromides and terminal aromatic alkynes using CO2 has been established. Various terminal aromatic alkynes and 2‐bromophenol by using CO2 with hydrosilane could be leveraged to provide various aurones in good yields under mild reaction conditions. Moreover, palladium‐catalyzed carbonylation reaction mechanism is proposed for the preparation of aurones.
Earliest archeological evidence of fertilization in Central Europe
Authors: Scharl Silviane , Zerl Tanja , Eckmeier Eileen , Gerlach Renate 
Published: July 2023

AbstractThe beginnings of food production—animal husbandry and crop cultivation—and of a sedentary way of life represent one of the most drastic changes in human history. Likewise, this is accompanied by an increasing human impact on nature, which is mainly caused by agricultural practices. Agriculture is related to the clearing of forests, tillage, maintenance of the cultivated land, and finally harvesting, which alters not only the vegetation cover but also soil fertility as there is a potential risk for a loss of nutrients. People already countered this loss of nutrients in the times of early agriculture through different techniques and practices. The article summarizes the earliest evidence of fertilization in the prehistory of Central Europe and presents the most important methods for their investigation. What significance fertilization had for early farming societies can presently not be estimated due to the small amount of data. We therefore advocate the development of a routine for sampling during archaeological excavations and for the analysis of various materials (sediment and plant remains) using various methods. For this, the awareness must be raised that anthropogenic sediments, such as pit fills, are important archives for research into the history of humankind.
Radiocarbon dating and isotopic palaeoecology of Glossotherium phoenesis from the Late Pleistocene of the Santa Elina rock shelter, Central Brazil
Authors: Pansani Thais Rabito , Dantas Mário André Trindade , Asevedo Lidiane , Cherkinsky Alexander , Vialou Denis , Vialou Águeda Vilhena , Pacheco Mírian Liza Alves Forancelli 
Published: July 2023

ABSTRACTThe Santa Elina rock shelter (Central Brazil) stands out with two human occupation layers with ground sloth fossil remains from the Late Pleistocene. Here, we explore the palaeontological aspect of this site. We update the taxonomic assignment of the ground sloth found in the shelter to Glossotherium phoenesis. Radiocarbon dating performed on bioapatite (14Cbioapatite) from two tooth specimens reveal the minimum ages of 14 944–15 239 cal a
bp (unit II2) and 22 339–22 534 cal a
bp (unit III4), which were converted to collagen using a novel approach and presented the calibrated ages of 17 450–17 906 cal a
bp (14Ccollagen = 14 547 ± 40) and 25 994–26 396 cal a
bp (14Ccollagen = 22 042 ± 40). We reinforce the chronology of the oldest unit of Santa Elina with material culture in association with megafauna bones to the Last Glacial Maximum. Carbon isotopic signatures suggest a mixed feeding diet for both specimens. The most recent ground sloth presents a higher isotopic value (δ13C = −1.8‰) and narrower niche breadth (BA = 0.50) than the oldest one (δ13C = −3.3‰; BA = 0.74). We conclude that G. phoenesis lived in an arboreal savanna habitat during the phases studied. Slightly different oxygen isotopic values (δ18O = 26.2‰ and 27.9‰) might suggest a decrease in humidity over time. Our results provide insights into the palaeoecology of the tropical Pleistocene G. phoenesis and the palaeoenvironmental setting of Santa Elina when occupied by early humans and megafauna during the Late Pleistocene.
Reimagining traumatic stress studies as a participatory science grounded in critical self‐reflection: A call to action
Authors: Henderson Zuleka , Kia‐Keating Maryam , Woods‐Jaeger Briana 
Published: July 2023

AbstractRecognizing the need for a transformative shift to advance scholarship and practice focused on traumatic stress, this paper emerged from a special invited panel at the 38th Annual Meeting of the International Society for Traumatic Stress Studies (ISTSS). The panel brought together scholars from interdisciplinary backgrounds, including psychology, public health, and social work, to share their unique perspectives and experiences harnessing a collaborative, critical, and strengths‐based lens in research. This piece invites the field to consider the importance of cultural humility as a foundational, nonnegotiable practice in traumatic stress studies. Details about participatory science and healing‐centered practice are presented along with key questions to support the application of these frameworks in studies of traumatic stress.
Exceptional poles of local spinor L‐functions of GSp(4) with anisotropic Bessel models
Authors: Rösner Mirko , Weissauer Rainer 
Published: July 2023

AbstractFor noncuspidal irreducible admissible representations of GSp(4, k) over a local non‐Archimedean field k, we determine the exceptional poles of the spinor L‐factor attached to anisotropic Bessel models by Piatetski–Shapiro. This completes the classification of spinor L‐factors for GSp(4, k).
Noise2Recon: Enabling SNR‐robust MRI reconstruction with semi‐supervised and self‐supervised learning
Authors: Desai Arjun D. , Ozturkler Batu M. , Sandino Christopher M. , Boutin Robert , Willis Marc , Vasanawala Shreyas , Hargreaves Brian A. , Ré Christopher , Pauly John M. , Chaudhari Akshay S. 
Published: July 2023

PurposeTo develop a method for building MRI reconstruction neural networks robust to changes in signal‐to‐noise ratio (SNR) and trainable with a limited number of fully sampled scans.MethodsWe propose Noise2Recon, a consistency training method for SNR‐robust accelerated MRI reconstruction that can use both fully sampled (labeled) and undersampled (unlabeled) scans. Noise2Recon uses unlabeled data by enforcing consistency between model reconstructions of undersampled scans and their noise‐augmented counterparts. Noise2Recon was compared to compressed sensing and both supervised and self‐supervised deep learning baselines. Experiments were conducted using retrospectively accelerated data from the mridata three‐dimensional fast‐spin‐echo knee and two‐dimensional fastMRI brain datasets. All methods were evaluated in label‐limited settings and among out‐of‐distribution (OOD) shifts, including changes in SNR, acceleration factors, and datasets. An extensive ablation study was conducted to characterize the sensitivity of Noise2Recon to hyperparameter choices.ResultsIn label‐limited settings, Noise2Recon achieved better structural similarity, peak signal‐to‐noise ratio, and normalized‐RMS error than all baselines and matched performance of supervised models, which were trained with more fully sampled scans. Noise2Recon outperformed all baselines, including state‐of‐the‐art fine‐tuning and augmentation techniques, among low‐SNR scans and when generalizing to OOD acceleration factors. Augmentation extent and loss weighting hyperparameters had negligible impact on Noise2Recon compared to supervised methods, which may indicate increased training stability.ConclusionNoise2Recon is a label‐efficient reconstruction method that is robust to distribution shifts, such as changes in SNR, acceleration factors, and others, with limited or no fully sampled training data.
Performance of habitat offsets for species conservation in dynamic human‐modified landscapes
Authors: Rhodes Jonathan R. , Liu Yan , Wahyudi Agung , Maron Martine , Iftekhar Md Sayed , Brisbane Shantala 
Published: July 2023

Abstract

Biodiversity offsets are a popular policy tool for mitigating the impact of development on biodiversity, but the ecological success of offsets arise from complex interactions among socio‐economic, ecological and policy processes, making outcomes challenging to assess.

Many offset policies use habitat surrogates to determine offset requirements, rather than using direct measures of impacted biota, and this can lead to poor outcomes for species. One potential solution to this is for offsets to be delivered by a public agency (agency‐led) rather than by developers (developer‐led). This is because agencies may be able to strategically choose offset sites that maximise outcomes for species (e.g. abundance), while there may be little reason for developers to act strategically in this way when offset requirements are based purely on habitat surrogates. Yet, the success of a strategic agency‐led approach is likely to depend on patterns of development and offset site availability.

To examine this, we developed a novel integrated spatially explicit model of land‐use change, habitat, species abundance and offset regulation. We apply the model to the Queensland Government's Environmental Offsets Policy for koalas Phascolarctos cinereus in South East Queensland, Australia, and test how patterns of development and offset site availability influence the performance of agency‐led versus developer‐led offsets.

When potential offset sites were plentiful, agency‐led offsets tended to outperform developer‐led offset delivery for maximising koala abundance while achieving similar or better outcomes for habitat area. Yet, when potential offset sites were rare, the relative performance of agency‐led offset was often poor, and offset requirements for habitat area were less likely to be met. Different spatial patterns of development had little effect on the relative performance of agency‐led versus developer‐led offsets.

Our analysis shows that agency‐led offsets with strategic choices of offset sites can improve species' outcomes for habitat‐based offsets but can also risk failing to meet habitat area requirements when the availability of offset sites is low. Importantly, our integrated spatial model provides a holistic approach to assessing policy options for biodiversity offsets in dynamic human‐modified landscapes.

Read the free Plain Language Summary for this article on the Journal blog.
Exploring dimensions of bias‐based bullying victimization, school fairness, and school belonging through mediation analysis
Authors: Burgess Deanna L. , Kim Isak , Seon Youngwoon , Chatters Seria J. 
Published: July 2023

AbstractBias‐based bullying (BBB) is a serious problem for school‐aged adolescents. However, limited attention has been paid to the mechanism of how BBB may affect youths' sense of belonging to the school. The purpose of the current study was to understand the associations between BBB victimization, school belonging, and school fairness among school‐aged adolescents. The present study also examined whether school fairness mediated the link between BBB victimization and school belonging. Data were drawn from the “No Place For Hate” project, which examined bias‐based incidents, school equity, and school belonging of a school district. The analytic study sample consisted of 2600 middle and high school students. Results from a structural equation model revealed that BBB victimization was negatively related to school fairness and school fairness was positively linked to school belonging. BBB victimization was also inversely associated with school belonging. Furthermore, a significant mediation effect was found in that school fairness mediated the link between BBB victimization and school belonging. The findings highlight the importance of addressing perceived fairness given its mediating role between BBB victimization and school belonging.
Effectiveness of virtual reality‐based balance and gait in older adults with fear of movement: A systematic review and meta‐analysis
Authors: Percy David , Phillips Tyler , Torres Fabian , Chaleunphonh Michele , Sung Paul 
Published: July 2023

AbstractObjectiveTo summarize the current evidence from randomized controlled trials (RCTs) regarding the effectiveness of Virtual Reality (VR) training and functional mobility in older adults with fear of movement.TypeSystematic review and meta‐analysis of randomized clinical trials.MethodologyAn electronic search was performed using PubMed, Embase, Medline, SPORTDiscus, Scopus, and CINAHL. A data search from January 2015 to December 2022 and a manual electronic literature search were conducted to identify published RCTs. The effectiveness of VR‐based balance training for balance and gait was evaluated in older adults with a fear of movement, which was measured by the Timed Up and Go (TUG) test and the Falls Efficacy Scale (FES). Three reviewers independently performed the study selection, and the quality assessment of the included studies was performed using the Physiotherapy Evidence Database (PEDro) scale. The reporting was based on the new Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA) Guidelines.SynthesisThe search product produced 345 results, from which 23 full text articles were studied. Seven RCTs of good methodological quality, including 265 participants, were included in the review. Overall, the studies reported that VR had a significant improvement on the TUG (Cohen's d = −0.91 [−1.38; −0.44], p = 0.001), while the FES was not significantly different (Cohen's d = −0.54 [−1.80; 0.71] p = 0.40). The average for PEDro scores (6.14) was good, and the risk of bias revealed that more than one‐third of the studies correctly described the random sequence generation and allocation concealment procedures.ConclusionVR‐based training is effective on balance or gait training based on the TUG; however, there were mixed results to improve FES scores following VR intervention. These inconsistent results might be limited due to variations in the studies, including heterogeneous training paradigms, sensitive outcome measures, small sample sizes, and short intervention durations, which limit the validity of our findings. Future investigations should compare different VR protocols to help establish better guidelines for clinicians.
How to Read Out the Phonon Number Statistics via Resonance Fluorescence Spectroscopy of a Single‐Photon Emitter
Authors: Groll Daniel , Paschen Fabian , Machnikowski Paweł , Hess Ortwin , Wigger Daniel , Kuhn Tilmann 
Published: July 2023

AbstractIn today's development of quantum technologies a hybrid integration of phononic excitations becomes increasingly attractive. As natural quasi‐particle excitations in solid state systems, phonons couple to virtually any other excitation and therefore constitute a useful interaction channel between different building blocks in hybrid quantum systems. This work explores how the efficient light‐scattering properties of a single‐photon emitter and the appearance of characteristic sidebands in resonance fluorescence spectra, when interfaced with an arbitrary phonon quantum state, can be utilized for acousto‐optical transduction. Within reasonable approximations, an analytical description for the optical spectra in the low excitation limit is developed which can be used to read the number statistics of the initial phonon state from a given spectrum. It is shown that the readout is faulty in situations where relevant resonant transitions are forbidden due to vanishing Franck–Condon factors, especially when considering spectra with a noisy background. Two possible solutions to this problem are presented: (A) changing the detuning of the laser relative to the single‐photon emitter which modifies the relevant resonant transitions, or (B) increasing dissipation of the single‐photon emitter to promote off‐resonant transitions.
Synergistic Effect of Plasticizer and Cross‐Linking Agent on the Properties of Finger Millet Starch‐Based Film
Authors: Sharma Ritu , Gautam Naina , Giribabu Giribabu , Kumar Raj , Yadav Shashikant 
Published: July 2023

AbstractEdible films can be used for food packaging to extend the shelf life of foods and protect them from exposure to moisture, microorganisms, pathogens, and bacteria. In the present study, the effect of plasticization and cross‐linking, which are modification approaches for upgrading the properties of starch, are investigated. Glycerol and sorbitol are used as plasticizing agents, and succinic acid is used as a cross‐linking agent. The results demonstrate that the addition of glycerol and sorbitol to the film‐forming solutions reduces brittleness and increases peeling ability and flexibility upon drying. Furthermore, the film matrix supports improvements in water vapor permeability (WVP), swelling index (SI), and mechanical properties. The glycerol‐based finger millet starch (FMS) films exhibits better thermal stability than the sorbitol‐based FMS film. The microscopic images of the films show that the use of glycerol in the film improves compactness and homogeneity compared to sorbitol‐based FMS films.