bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Antioxidant Peptides Identified from Arthrospira platensis Hydrolysates Prepared by a Marine Bacterium Pseudoalteromonas sp. JS4-1 Extracellular Protease
Authors: Liu Congling , Chen Gong , Rao Hailian , Xiao Xun , Chen Yidan , Wu Cuiling , Bian Fei , He Hailun 
Published: February 2023

Crude enzymes produced by a marine bacterium Pseudoalteromonas sp. JS4-1 were used to hydrolyze phycobiliprotein. Enzymatic productions showed good performance on DPPH radical and hydroxyl radical scavenging activities (45.14 ± 0.43% and 65.11 ± 2.64%, respectively), especially small peptides with MWCO <3 kDa. Small peptides were fractioned to four fractions using size-exclusion chromatography and the second fraction (F2) had the highest activity in hydroxyl radical scavenging ability (62.61 ± 5.80%). The fraction F1 and F2 both exhibited good antioxidant activities in oxidative stress models in HUVECs and HaCaT cells. Among them, F2 could upregulate the activities of SOD and GSH-Px and reduce the lipid peroxidation degree to scavenge the ROS to protect Caenorhabditis elegans under adversity. Then, 25 peptides total were identified from F2 by LC-MS/MS, and the peptide with the new sequence of INSSDVQGKY as the most significant component was synthetized and the ORAC assay and cellular ROS scavenging assay both illustrated its excellent antioxidant property.
Antibacterial Activity of Ulva/Nanocellulose and Ulva/Ag/Cellulose Nanocomposites and Both Blended with Fluoride against Bacteria Causing Dental Decay
Authors: Hamouda Ragaa A. , Qarabai Fauzia A. K. , Shahabuddin Fathi S. , Al-Shaikh Turki M. , Makharita Rabab R. 
Published: February 2023

One of the most prevalent chronic infectious disorders is tooth decay. Acids produced when plaque bacteria break down sugar in the mouth cause tooth decay. Streptococcus mutans and Lactobacillus acidophilus are the most prominent species related to dental caries. Innovative biocidal agents that integrate with a biomaterial to prevent bacterial colonization have shown remarkable promise as a result of the rapid advancement of nanoscience and nanotechnology. In this study, Ulva lactuca was used as a cellulose source and reducing agent to synthesize nanocellulose and Ulva/Ag/cellulose/nanocomposites. The characterizations of nanocellulose and Ulva/Ag/cellulose/nanocomposites were tested for FT-IR, TEM, SEM, EDS, XRD, and zeta potential. Ulva/Ag/cellulose/nanocomposites and Ulva/nanocellulose, both blended with fluoride, were tested as an antibacterial against S. mutans ATCC 25175 and L. acidophilus CH-2. The results of the SEM proved that nanocellulose is filament-shaped, and FT-IR proved that the functional groups of Ulva/nanocellulose and Ulva/Ag/cellulose/nanocomposites and cellulose are relatively similar but present some small diffusion in peaks. The TEM image demonstrated that the more piratical size distribution of Ulva/Ag/cellulose/nanocomposites ranged from 15 to 20 nm, and Ulva/nanocellulose ranged from 10 to 15 nm. Ulva/Ag/cellulose/nanocomposites have higher negativity than Ulva/nanocellulose. Ulva/Ag/cellulose/nanocomposites and Ulva/nanocellulose possess antibacterial activity against S. mutans ATCC 25175 and L. acidophilus CH-2, but Ulva/Ag/cellulose/nanocomposites are more effective, followed by that blended with fluoride. It is possible to use Ulva/Ag/cellulose/nanocomposites as an antimicrobial agent when added to toothpaste. It is promising to discover an economic and safe nanocomposite product from a natural source with an antimicrobial agent that might be used against tooth bacteria.
PTERIDOPHYTA DI DAERAH ALIRAN SUNGAI KELINGI KECAMATAN LUBUKLINGGAU UTARA II SUMATERA SELATAN
Authors: Krisnawati Yuni , Wardiyanti Yunita 
Published: February 2023

Tujuan penelitian ini adalah untuk mengetahui jenis-jenis tumbuhan paku yang ada di daerah aliran Sungai Kelingi Kecamatan Lubuklinggau Utara II Sumatera Selatan. Metode yang digunakan adalah survei deskriptif. Pengambilan sampel dilakukan dengan teknik jelajah bertujuan (purposive sampling) dan dokumentasi. Penelitian ini dilakukan pada Agustus sampai Oktober 2020. Parameter yang diamati yaitu ciri-ciri morfologi (akar, batang, daun dan sorus), serta habitat. Identifikasi merujuk kepada buku A. G. Piggott. 1988. Ferns Of Malaysia in Colour. Hasil penelitian menunjukkan bahwa ada 19 jenis dari 11 family tumbuhan paku (Pteridophyta).Â Â Kata Kunci:Pteridophyta, Sungai Kelingi, Lubuklinggau
DOSEN TIDAK SIAP MENGHADAPI PANDEMI: KAJIAN PERMASALAHAN ISOLASI DIGITAL PADA PEMBELAJARAN DARING
Authors: Abrori Fadhlan Muchlas 
Published: February 2023

Penelitian ini bertujuan untuk mengidentifikasi permasalahan yang dialami dosen selama pembelajaran daring. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian studi kasus. Subjek penelitian merupakan dosen Fakultas Keguruan dan Ilmu Pendidikan, Universitas Borneo Tarakan. Dari data yang dikumpulkan terdapat tiga permasalahan yang dialami dosen selama pandemi. Permasalahan tersebut diantaranya manajemen waktu dalam mempersiapkan media, permasalahan teknik (koneksi, gawai, dan lainnya), dan kurangnya keterampilan dalam penggunaan platform digital.Â Kata kunci: permasalahan, dosen, pembelajaran daring
PENGEMBANGAN HANDOUT BERMUATAN PENDIDIKAN KARAKTER BERBASIS KONTEKSTUAL PADA MATERI KINGDOM PLANTAE DI KELAS X SMAK FRATER DON BOSCO TARAKAN
Authors: Siahaan Susi Yantika , Wijarini Fitri , Adhani Aidil 
Published: February 2023

AbstrakPenelitian ini bertujuan untuk menghasilkan Handout Bermuatan Pendidikan Karakter Berbasis Kontekstual Pada Materi Kingdom Plantae di Kelas X SMAK Frater Don Bosco Tarakan yang berkualitas dari segi kelayakan dan respon siswa. Penelitian ini merupakan jenis penelitian Research and Development (RD) dengan menggunakan model pengemmbangan 4-D yang terdiri dari 4 tahapÂ yaitu Define, Design,Â Development, Disseminate. Akan tetapi, pada pengembangan ini hanya dilakukan sampai tahap ke 3 yaitu tahap Development. Data penelitian dianalisis melalui uji kelayakan dan respon siswa. Pengujian produk dilakukan oleh validator ahli media, ahli materi, dan praktisi (guru biologi). Uji coba lapangan dilakukan secara online melalui google formulir yang dibagikan pada siswa SMAK Frater Don Bosco Tarakan kelas XI IPA dengan jumlah siswa sebanyak 30 orang. Hasil validasi yang diperoleh dari ahli media sebesar 89% dengan kategori sangat layak, ahli materi sebesar 96% dengan kategori sangat layak, praktisi sebesar 94% dengan kategori sangat layak dan respon siswa sebesar 87% dengan kategori sangat menarik. Berdasarkan hasil penelitian tersebut, maka dapat disimpulkan bahwa Handout Bermuatan Pendidikan Karakter Berbasis Kontekstual Pada Materi Kingdom Plantae yang dikembangkan telah memenuhi kriteria kualitas bahan ajar yang baik dan layak digunakan dalam pembelajaran biologi di sekolah.Kata Kunci: Bahan Ajar, Handout, Pendidikan karakter, Kontekstual.AbstractÂ This study aimed to produce high quality handouts with contextual-based character education on Kingdom Plantae Material for tenth Grade Students of SMAK Frater Don Bosco Tarakan in terms of student eligibility and response. This Research and Development (RD) study used a 4-D development model consisting of 4 stages, namely Define, Design, Development was only carried out until the 3 rdÂ stage (Deveopment stage). The research data were analyzed through feasibility test and student responses. Product testing was validated by media expert, material experts, and practitioners (biology tearchers). Field trials were carried out online via a google form which was distributed to a total of 30 students.Â The validations result obtained from media experts were 89% which meant very feasible, 96% from material experts meaning feasible, 94% from practitioners meaning very feasible, 87% from student response meaning very interesting. It could be concluded that the handout with Contextual-Based Character Education on the Kingdom Plantae material developed met the criteria for good quality teaching materials and was suittable for use in learning biology in the school.Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Keywords:Â Teaching Materials, Handouts, Character education, Contextual.
INVENTARISASI PENGOLAHAN TUMBUHAN OBAT DI KECAMATAN LUBUKLINGGAU UTARA I
Authors: Arif M. Furqon , Triyanti Merti , Widiya Mareta 
Published: February 2023

AbstrakPenelitian ini bertujuan mengetahui cara pengolahan tumbuhan obat di Kecamatan Lubuklinggau Utara I. Penelitian ini dilaksanakan di Kecamatan Lubuklinggau Utara I. Teknik pengumpulan data berupa observasi, wawancara, dan dokumentasi tumbuhan obat. Teknik analisis data menggunakan teknik deskriptif kualitatif yaitu data hasil wawancara dikelompokkan. Hasil penelitian ditemukana 202 jenis tumbuhan obat yang terdiridari 26 famili. Sementara itu untuk pengolahannya ditemukan 8 teknik pengolahan tumbuhan obatKata kunci Inventarisasi, Tumbuhan Obat, cara pengolahanÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â AbstractThis study aims to determine the way of utilization of medicinal plants in the District of North Lubuklinggau I. The date collection techniques were observation, interviews and documentation of medicinal plants. The date analysis technique used a qualitive descriptive technique, namely the date from interviews. The results of the study found 202 types of medicinal plants consisting of 26 families. In addition, for the utilization researchers found 8 ways to use the medicinal plants.Â Keywords Inventory, Medicinal Plants, utilization
INVENTARISASI JENIS-JENIS TUMBUHAN OBAT DI KECAMATAN SALING KABUPATEN EMPAT LAWANG
Authors: Dianci Pipi Deka , Triyanti Merti , Harmoko Harmoko 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui jenis-jenis tumbuhan obat, bagian-bagian yang dimanfaatkan dan cara pengolahan tumbuhan obat di Kecamatan SalingÂ KabupatenÂ Empat Lawang. Penelitian ini dilaksanakan di Tujuh Desa yang berada di Kecamatan Saling. Teknik pengumpulan data berupa observasi, wawancara,Â dan dokumentasi tumbuhan. Teknik analisis data mengunakan teknik deskriptif kualitatif yaitu data hasil wawancara dikelompokkan berdasarkan spesies tumbuhan obat, bagian-bagian yang di manfaatkan serta cara pengolahannya yang diketahui oleh masyarakat di kecamatan Saling. Hasil penelitian yangÂ ditemukan 78 jenis tumbuhan obat yang terdiri dari 46 famili. Bagian yang paling banyak digunakan adalah bagian daun dari tumbuhan yang dijadikan sebagai obat dan bagian yang paling sedikit digunakan adalah lendir, biji, dan umbi. Cara pengolahan tumbuhan obat yang digunakan oleh masyarakat di Kecamatan Saling masih sangatÂ sederhana, yang paling banyak mengelolah tumbuhan untuk obat dengan cara di rebus dan yang paling sedikit dengan cara diiris, dilalap, dilayukan, ditetes, dan di panaskan.Â Â
NATURE OF MODEL (NoM) DALAM PEMBELAJARAN SAINS
Authors: Nurafina Eka , Roshayanti Fenny , Dzakiya M. Anaz , Hayat Muhammad Syaipul 
Published: February 2023

Materi pembelajaran sebagai salah satu sumber belajar utama bagi siswa di dalam kegiatan pembelajaran tidak bisa diabaikan dan perlu dipilih secara tepat, Model dapat digunakan untuk meningkatkan pemahaman dan kemampuan sains siswa. Model yang digunakan tanpa pemahaman kuat justru akan menghambat pemahaman siswa. Tujuan dari penelitian ini untuk mengetahui Nature of Model (NoM) dalam pembelajaran sains. Metode penelitian ini yaitu penelitian kualitatif dengan teknik pengolahan data berupa analisis deskriptif hasil studi literatur. Kemudian data dianalisis menggunakan tiga jalur yaitu kondensasi data, penyajian data dan penarikan kesimpulan. Hasil dari penelitian berdasarkan studi literatur yaitu Nature of Model (NoM) memiliki banyak kelebihan jika diterapkan pada pembelajaran sains. Nature of Model (NoM) dalam pembelajaran sains mampu membantu meningkatkan pemahaman, kemampuan berfikir dan kemampuan literasi sains siswa. Namun dalam menentukan model dalam pembelajaran sains haruslah tepat. Agar materi abstrak yang ingin tersampaikan tidak menimbulkan kesalahpahaman persepsi oleh siswa.Â Â
ANALISIS KETERAMPILAN PROSES SAINS MAHASISWA MELALUI PEMBELAJARAN BERBASIS PROYEK
Authors: Ilma Silfia , Nursia Nursia 
Published: February 2023

Keterampilan proses sains berperan dalam pengembangan keterampilan mahasiswa dalam memeroleh fakta, konsep, dan pelibatan keterampilan berpikir tingkat tinggi. Tujuan penelitian ini adalah menganalisis keterampilan proses sains mahasiswa dalam pembelajaran berbasis proyek selama pandemi COVID-19. Metode dalam penelitian ini adalah deskriptif. Instrument penelitian yang digunakan adalah lembar observasi keterampilan proses sains. Teknik analisis data dengan menggunakan persentase. Hasil penelitian diperoleh bahwa aspek obeservasi persentase 82 kategori sangat baik, prediksi persentase 80 kategori baik, melakukan pengukuran persentase 73 kategori baik, berkomunikasi persentase 85 kategori sangat baik, dan klasifikasi persentase 71 kategori baik. Kesimpulan dalam penelitian ini adalah keterampilan proses sains mahasiswa selama masa pandemic COVID-19 tertinggi pada aspek berkomunikasi dengan persentase 85 kategori sangat baik. Kemudian terendah pada aspek klasifikasi dengan persentase 71 kategori baik.Â Penerapan pembelajaran berbasis proyek secara online direkomendasikan dalam memberdayakan keterampilan proses sains mahasiswa.
Plasma processing technique by combination of plasma-assisted reactive sputtering and plasma annealing for uniform electrical characteristics of InGaZnO thin film transistors formed on large-area substrates
Authors: Takenaka Kosuke , Yoshitani Tomoki , Endo Masashi , Hirayama Hiroyuki , Toko Susumu , Uchida Giichiro , Ebe Akinori , Setsuhara Yuichi 
Published: February 2023

Abstract
The homogeneous formation of high-mobility oxide semiconductor thin films over large areas at low temperatures was accomplished by optimizing both the film formation process and the low-temperature post-processing via plasma annealing. Increasing the substrate-to-target distance (D
ST) and the applied target voltage was found to produce more uniform deposition. The results of the field-effect mobility distributions of IGZO TFTs processed using plasma annealing were founded that plasma annealing generated essentially uniform distributions with μ
FE values in the range of 32–35 cm2 V−1 s−1.
Low-power and high-resolution capacitance sensing using CMOS inverter-based RC oscillator by employing voltage-integration feedback
Authors: Li Zixuan , Lee Sangyeop , Ishihara Noboru , Ito Hiroyuki 
Published: February 2023

Abstract
In this paper, new circuit techniques are proposed and applied for low-power, high-resolution capacitance sensing. The first is a CMOS inverter-based resistor-capacitor oscillator that consists of a resistor, a capacitor, and three inverters, allowing it to operate at low supply voltage and low power with a wide sensing range. The second is a voltage-integration feedback (VIF), which suppresses low-frequency jitter noise generated by internal and external noise. As a result, a fabricated circuit with a 0.18 μm CMOS process technology exhibits the sensitivity of 10.5 μs pF−1 with 2.12 ppm resolution in the oscillation frequency, in addition to 7.52 μW power consumption under a 1 V power supply.
Performance improvement of in-materio reservoir computing by noise injection
Authors: Hakoshima Masaya , Usami Yuki , Kotooka Takumi , Tanaka Hirofumi 
Published: February 2023

Abstract
Computation performance of in-materio reservoir device was evaluated by varying intensity of noise injection. Materials for the reservoir device was synthesized using a α-Fe2O3/titanium bismuth oxide composite by using the sol–gel method. The prepared samples were characterized by conducting X-ray diffractmetry, transmission electron microscopy, and energy dispersive X-ray spectroscopy to confirm presence of α-Fe2O3, TiO2, and Bi4Ti3O12 nanoparticles. The I–V and V–t curves show nonlinearity, and phase differences between input and output signals, and the fast Fourier transform of the V–t curve showed high harmonics at the input sine wave with 11 Hz of frequency. In the waveform prediction task, the prediction accuracy was improved only when a small intensity of white noise voltage was superimposed to the input information signal.
Intrathecal midazolam is a comparable alternative to fentanyl and nalbuphine as adjuvant to bupivacaine in spinal anesthesia for elective Cesarean Section; a randomized controlled double-blind trial
Authors: Amin, MD Samar Rafik , , MD Ibrahim Souidan , Abdelzaam Elsayed M. 
Published: February 2023

Background: Different adjuvants have been introduced to enhance the quality of local anesthetics and reduce its adverse events. This study was directed to compare the anesthetic and analgesic properties of intrathecal hyperbaric bupivacaine when three different adjuvant drugs were added.
Methodology: One hundred full-term parturients aged 18 to 40 years, scheduled for elective cesarean section, were randomly assigned to 4 groups. Each group received 12.5 mg of 0.5% hyperbaric bupivacaine combined with either 0.5 ml saline (Group-B), 25µg fentanyl (Group-F), 0.8 mg nalbuphine (Group-N) or 2 mg midazolam (Group-M). The outcomes included the postoperative effective analgesia time, the sensorimotor characteristics, postoperative VAS score, pethidine consumption, maternal complications, and neonatal Apgar score.
Results: Earlier onset of sensory and motor block was observed in Group F and N than in Group B and M. Duration of postoperative effective analgesia was longer in Groups F, N and M (252.42 ± 46.11, 227.34 ± 36.54 and 243.71 ± 44.95 hours, respectively) than in Group B (172.11 ± 20.99) (P < 0.001). VAS scores decreased in adjuvant groups during the first 12 hours postoperative and required pethidine doses were less.
Conclusion: Addition of adjuvant agents to intrathecal bupivacaine improved the quality of subarachnoid block without increasing side-effects. Intrathecal midazolam provided comparable outcomes as the frequently used opioids.
Abbreviations: CS: Cesarean section; LA: Local anesthetics; SA: Spinal anesthesia
Key words: Intrathecal; Nalbuphine; Midazolam; Fentanyl; Postoperative analgesia; Cesarean section.
Citation: Amin SR, Souidan I, Abdelzaam EM. Intrathecal midazolam is a comparable alternative to fentanyl and nalbuphine as adjuvant to bupivacaine in spinal anesthesia for elective cesarean section: a randomized controlled double-blind trial. Anaesth. pain intensive care 2022;27(1):89−96; DOI: 10.35975/apic.v27i1.1923
Received: June 26, 2022; Reviewed: November 28, 2022; Accepted: December 14, 2022
Adductor canal block as an adjuvant in a multimodal analgesia protocol vs. multimodal analgesia alone for total knee arthroplasty
Authors: Mohsen Ahmed Radwa Khairy Abd El , Mohamed Ahmed Saeed , Nassef John Nader , Elsatar Yasmin Hassan Abd , Fawal Sanaa Mohamed Mohamed El 
Published: February 2023

Background & Objective: Effective analgesia is necessary for early postoperative recovery following total knee arthroplasty (TKA). Various combinations of pain relief modalities have been used for postoperative pain in TKA. Adductor canal block (ACB) has been suggested to have a role in this scenario. We evaluated the effectiveness of ACB following spinal anesthesia (SA) in terms of postoperative pain relief, early ambulation and patient satisfaction.
Methodology: A total of 72 patients were enrolled in the study. Out of these 36 patients (Group A) were randomized to receive ACB in addition to SA, while 36 patients (Group B) received only SA. Postoperative numerical rating scale (NRS) score, and morphine consumption were noted at shifting to PACU, at 6, 12, 18 and 24 h postoperatively as a primary outcome measure. As a secondary outcome measures, quadriceps muscle power, time to ambulation and patient satisfaction were evaluated.
Results: A statistically significant drop in NRS was noted in Group A, at 6, 12, 18, and 24 h after surgery, but not in the postoperative care unit (P = 0.75), and a decrease in the total morphine use among patients who underwent an ACB. A significant change was noted in ambulation and patient satisfaction in the Group A, with no significant change in quadriceps muscular power among both groups.
Conclusion: ACB as a part of pain management strategy is successful in reducing postoperative pain, morphine consumption, enabling early ambulation, and elevating patient satisfaction.
Key words: Adductor canal block; Spinal Anesthesia; Total knee arthroplasty
Citation: Ahmed RKA, Mohamed AS, John Nader Nassef JN, Abd Elsatar YH, El Fawal SMM. Adductor canal block as a part of multimodal analgesia protocol for total knee arthroplasty. Anaesth. pain intensive care 2022;27(1):31−36; DOI: 10.35975/apic.v27i1.1941
Received: August 18, 2022; Reviewed: November 5, 2022; Accepted: November 19, 2022
Efficacy of dexmedetomidine as an adjuvant in erector spinae plane block in breast cancer surgery: a randomized controlled trial
Authors: Hassan, MD Mohamed Elsayed , MD Ahmed S. Abdelgalil, 
Published: February 2023

Background: The erector spinae plane block (ESPB) is a new potential inter-fascial block technique used to decrease pain after breast surgery. Dexmedetomidine (Dex) is used as an adjuvant to local anesthetics and is thought to improve the analgesic profile and duration of different anesthetic techniques. We evaluated the effect of adding Dex in local anesthetic solution for ESPB in breast cancer surgeries regarding the analgesic effect and duration.
Methodology: This prospective randomized controlled study included 60 female patients scheduled for breast cancer surgery. All patients were anesthetized in a standard manner, and then were randomized into three equal groups; 1. ESP group, to receive an ultrasound-guided ESPB with 20 ml bupivacaine 0.5%; 2. Dex group, to receive ESPB with 19 ml bupivacaine 0.5% and 1 ml of normal saline containing 1 µg/kg Dex, and the control group received the standard general anesthesia only. The intraoperative fentanyl and postoperative morphine consumption were noted. Postoperative pain was assessed on numerical pain rating scale (NRS)
Results: The duration of analgesia was significantly prolonged in ESPB and Dex groups than in the control group and in the Dex group than in ESPB group (P < 0.001). Intraoperative fentanyl and postoperative morphine consumption were significantly lower in ESPB and Dex groups than in the control group. NRS pain scores were comparable in the three groups during the first 24 h.
Conclusions: Adding dexmedetomidine 1 µg/kg to bupivacaine 0.5% prolongs the duration of analgesia of the ESPB in breast cancer surgeries.
Key words: Analgesia; Breast Cancer; Breast Surgery; Bupivacaine; Dexmedetomidine; Nerve Block
Citation: Hassan ME, Abdelgalil AS. Efficacy of dexmedetomidine as an adjuvant in erector spinae plane block in breast cancer surgery: a randomized controlled trial. Anaesth. pain intensive care 2022;27(1):16−22; DOI: 10.35975/apic.v27i1.2109
Received August 16, 2022; Reviewed: November 13, 2022; Accepted: December 03, 2022