bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic fermentation quality and bacterial community structure of paper mulberry silage from three regions of China
Authors: Guo Linna , Wang Yuan , Wang Xuekai , Li Xiaomei , Xiong Yi , Lin Yanli , Ni Kuikui , Yang Fuyu 
Published: June 2023

Abstract
Background
Paper mulberry has been regarded as a potential protein resource for relieving the forage supply crisis, and ensiling has become the most important method for preserving it. An in-depth analysis of the fermentation characteristics of paper mulberry silage could provide a theoretical basis for producing high-quality silage. In this study, we aimed to investigate the dynamic fermentation quality and bacterial community of paper mulberry silages harvested from different regions in China.

Results
The results showed an increased trend in ammonia nitrogen (NH3-N) concentration, despite a decrease in pH with prolonged ensiling days. Furthermore, fermentation patterns varied among paper mulberry silages from three regions. Paper mulberry from Zhuozhou, Hebei (HZ) showed the highest dry matter (DM) content and a slight decrease in pH during ensiling. While the lowest DM content was observed in Hechi, Guangxi (GH), which exhibited abnormal fermentation in the silage. In particular, silage from Lankao, Henan (HL) exhibited the best fermentation quality, with lower pH and NH3-N concentration, and higher lactic acid concentration than others (P < 0.05). The bacterial richness and evenness also declined with prolonged ensiling. Among all samples, Enterobacter was the most abundant in all silages, with a trend of increasing and then decreasing during the fermentation process. Pseudocitrobacter dominated in GH silage with abnormal fermentation. Although the bacteria community during ensiling varied widely among silages from different regions, Enterobacter cloacae and Lactobacillus plantarum were the main differential bacteria in silage quality of paper mulberry.

Conclusion
Ensiling days and regions had significant effects on the fermentation patterns and bacterial community of paper mulberry silage which might be due to the differences in DM content. Notably, silage quality showed a close relationship with Enterobacter cloacae and Lactobacillus plantarum. Inhibiting the proliferation of Enterobacter and Pseudocitrobacter could be critical for improving the fermentation quality of paper mulberry silage.

Graphical Abstract
Morphological and radiological mapping of dental cusps in relation to spatial constraints on tooth shape of one-humped camel (Camelus dromedarius)
Authors: Erasha Atef M. , Nazih Mohammed , Ali Safwat , Alsafy Mohamed , El-gendy Samir , Sayed Ramy K. A. 
Published: June 2023

AbstractA significant number of researches in veterinary study have been focused on dental structure; however, there are few on the orientation and identification of their cusps. Therefore, the present article aimed to spotlight the arrangement pattern of dental cusps in the camel as a folivorous and graminivorous animal. This study was conducted on eight heads of adult, healthy camels of both sexes, collected from slaughter houses. To determine the exact orientation of cusps of molar teeth, additional radiological and CT scans were performed on the mandible as a landmark that should facilitate the reading of the cusps map. It was evident that the cusps are arranged in crescentic appearance, selenodontal form, with two cusps on each side, paracone and hypocone on the lingual surface and protocone and metacone on the vestibular aspect. Thus, camels cannot wear bite like equines, which would interfere with their constant chewing method. The camels’ dental cusps provide some of the finest examples of convergent evolution, which offer insights both into correlates between form and function, and into the ability of euthomorphic cusps in intrapability and stabilization of food items and their comminution between formidable cusps and occlusal spillway in between. Further studies should be done on the brachydont teeth and tropospheric cusps to fill the functional anatomy gap of teeth, in addition to diversity of cusps form. This study is considered a basic comparative anatomical study for normal healthy dentition and forensic practice, in addition to its importance in detection of more local aspects of dental problems in camels.
The effects of Kinesio tapes on facial swelling following bimaxillary orthognathic surgery in the supraclavicular region
Authors: Golkar Mohsen , Taheri Anita , Alam Mostafa , Asadi Yasin , Keyhan Seied Omid 
Published: June 2023

Abstract
Background
Several osteotomies are required for orthognathic surgery to reposition the jaws correctly. This study aimed to evaluate whether Kinesiotaping can reduce swelling, pain, and trismus following orthognathic surgery of the facial skull.

Materials and methods
The present study consists of two phases. In the split-mouth phase, 16 skeletal class III patients underwent Bimax Orthognathic surgery, and Kinesiological tape (KT) was applied on one half of the face. In the prospective case–control phase, 30 patients were divided into two groups. Kinesio tape was applied on both sides of the face of the Kinesio group, and pressure dressing and ice therapy were used for the second group. The tape was parallel to the lower border of the mandible along its entire length, tangent to the labial commissure area on the studied side. The tape was placed in place for 5 days. Edema was evaluated by measuring the distance from the menton to the lower edge of the tragus. The maximum mouth-opening trismus was evaluated, and the VAS index was used to evaluate pain.

Results
There was evidence of swelling reduction after KT; within the same study, differences between the left and right sides as well as for the same side were statistically significant (p < 0.001). As a result of tapping lymphatic Kinesio tape on the affected area, tension was reduced, and lymphatic circulation was restored. Blood and lymph microcirculation was improved, enabling the body to heal itself.

Conclusion
Kinesio tape reduced swelling after orthognathic surgery in a positive way. As a simple, non-traumatic, economical method, Kinesio taping seems promising.
Role of the newly established Renal Replacement Therapy Professional Instructor in Japan and the future direction of renal replacement therapy
Authors: Kawaguchi Yuki , Hanafusa Norio , Tsuchiya Ken 
Published: June 2023

AbstractApproximately 340,000 people in Japan are on chronic dialysis, and this number continues to increase. Even today, hemodialysis is the most frequently selected modality for renal replacement therapy in Japan, accounting for approximately 97% of chronic dialysis patients. This is because the facilities and insurance for hemodialysis were developed early in Japan, and the results of treatment were very good. Most cases of kidney disease are associated with diabetes or hypertension, and the average age of patients on dialysis is increasing, which means that many dialysis patients experience reduced activities of daily living (ADL) and quality of life (QOL). To address those issues, shared decision-making and advance care planning are now widely used in the process of selecting RRT. Because of the work required, including multiple processes and information sharing, medical professionals must practice team medicine in order to improve ADL and QOL for dialysis patients and renal transplant recipients as well as promote appropriate selection of RRT. Accordingly, the “Renal Replacement Therapy Professional Instructor” certification system was established to meet this need. In addition, due to the aging of dialysis patients, there are more situations where it is necessary to consider forgoing dialysis in terms of general condition and QOL. In such cases, conservative kidney management must be offered, and the “Renal Replacement Therapy Professional Instructor” is also required to participate in them. It is hoped that a comprehensive medical system centered around Renal Replacement Therapy Professional Instructors will be created to meet the increasingly diverse needs of patients with end-stage kidney disease and their families, with the aim of providing support that will enable them to lead richer lives.
Heterogeneity in susceptibility to polycystic ovary syndrome among women with epilepsy
Authors: Sha Leihao , Wu Yiming , Lai Wanlin , Duan Yifei , Xia Yilin , Chen Lei 
Published: June 2023

Abstract
Background
Epilepsy comorbidities adversely affect the quality of life of patients. Women with epilepsy are at a high risk of comorbid endocrine disorders. Among them, the polycystic ovary syndrome (PCOS) has a threefold higher prevalence in women with epilepsy than in healthy women and is the main cause of infertility among the patients. Clinically, women with epilepsy show heterogeneity in the susceptibility to PCOS. This heterogeneity may be associated with genetic factor.

Methods
To test this, we retrospectively collected clinical data from 45 female patients with epilepsy and divided them into three groups according to their susceptibility to PCOS. Groups A and B represented a high susceptibility to PCOS. Patients in Group A were diagnosed with PCOS before their first seizure, while patients in Group B were diagnosed with PCOS after a short period of monotherapy with a low dose of antiseizure medication (ASM) following the diagnosis of epilepsy. Patients in Group C did not develop PCOS despite a prolonged treatment with high-dose ASM. We compared the clinical data and genetic profiles among the three groups.

Results
We found a clear trend of impaired metabolism in Group B patients and this may be associated with high-frequency mutations in MYO10 and ADGRL3.

Conclusions
Our study suggests that women with epilepsy are heterogeneous in the susceptibility to PCOS and this is associated with mutations in specific genes. Therefore, genetic screening should be conducted to screen for women with epilepsy who are more likely to have comorbid PCOS, so that they can receive targeted interventions at an early stage to reduce the risk.
Analysis of genetic variants in the exon 2 and 3 of autosomal DAZLA gene among infertile South Indian men
Authors: Nongthombam Puja Devi , Malini Suttur S. 
Published: June 2023

Abstract
Background
Boule, DAZLA, and DAZ are members of the Deleted in Azoospermia family of genes, which play significant roles in gametogenesis and are important fertility factors in humans. In a few studies, deletion of the Y chromosomal DAZ cluster and single nucleotide polymorphisms in the DAZLA gene were reported to affect male fertility, although this is paradoxical because they were found in both control and fertile men. As a result, the goal of this study was to check if Y chromosomal DAZ cluster deletion and SNPs in the DAZLA gene on chromosome 3 of humans are associated to male infertility in the population. For computational analysis, different bioinformatics tools such as SIFT, PolyPhen2, Mutation Taster, FATHMM, and PROVEAN were used to analyse mutations.

Results
Within the studied population, we found no association between DAZ deletion and the most prevalent DAZLA SNPs A260G (rs11710967) and A386G (rs1219183446). We also discovered two new deleterious genetic variations in exon 3 of the DAZLA gene, one nonsynonymous mutation that replaced Valine with Glutamate at the 66 codon position and the other a stop gain mutation at the 74 amino acid position. These genetic changes are found in the RRM domain of the DAZLA gene, which is confirmed by Motif scan analysis and results in a change in the DAZLA protein's secondary structure. The RRM domain is a highly conserved regulatory domain for mRNA transport and translation. Azoospermia and necrospermia infertility phenotypes were shown in infertile male samples with these genotypes.

Conclusion
We can conclude that further investigation of the aforesaid new mutations in the DAZLA gene may be valuable in understanding their significance in male infertility in different populations due to the multifactorial nature of male infertility and arrays of gene expression required at every stage of spermatogenesis.
Impact of pulmonary valve replacement on left and right ventricular function using strain analysis, in children with repaired tetralogy of Fallot
Authors: Moradian Maryam , Rashidighader Fariba , Golchinnaghash Fatemeh , Meraji Mahmoud , Ghaemi Hamid Reza 
Published: June 2023

Abstract
Background
In repaired Tetralogy of Fallot (rTOF), pulmonary regurgitation and resulting right ventricular (RV) and left ventricular (LV) dysfunction are associated with adverse clinical outcomes. We performed an echocardiographic assessment of LV and RV function using Global Longitudinal Strain (GLS) and conventional echo method prior to and following Pulmonary Valvular Replacement (PVR) to help inform proper timing of operation.

Results
A total of 30 rTOF patients (12.17 ± 2.5 years, 70% male) were included. Regarding to LV function, the study revealed a significant reverse correlation between LV GLS (absolute value) and early (mean = 10.4 days) and late (mean = 7.4 months) postop LVEF. Paired T-Test showed significant difference between GLS of LV and RV before and late after operation (op), however, without significant changes early postop. Late postop significant improvements occurred in other conventional echo indices of LV and RV function as well. There was also a significant correlation between echo-measured LVEF & Fraction Area Change (RV FAC) and MRI-derived LVEF & RVEF, respectively.

Conclusion
In this cross-sectional study in rTOF patients, RV and LV GLS as well as conventional echocardiographic indices regarding LV and RV function improved significantly after 6 months (mean = 7.4mo) following PVR.
Ready, set, go! The role of organizational readiness to predict adoption of a family caregiver training program using the Rogers’ diffusion of innovation theory
Authors: Van Houtven Courtney H. , Drake Connor , Malo Teri L. , Decosimo Kasey , Tucker Matthew , Sullivan Caitlin , D’Adolf Josh , Hughes Jaime M. , Christensen Leah , Grubber Janet M. , Coffman Cynthia J. , Sperber Nina R. , Wang Virginia , Allen Kelli D. , Hastings S. Nicole , Shea Christopher M. , Zullig Leah L. 
Published: June 2023

Abstract
Background
Caregivers FIRST is an evidence-based program addressing gaps in caregivers’ skills. In 2020, the Veterans Health Administration Caregiver Support Program (CSP) nationally endorsed Caregivers FIRST, offering credit in leadership performance plans to encourage all VA medical centers (VAMCs) to implement locally. This study examines the association of organizational readiness with VAMC adoption of Caregivers FIRST.

Methods
In a cohort observational study, we surveyed CSP managers about their facilities’ readiness to implement using the Organizational Readiness for Implementing Change (ORIC) instrument and compared change commitment and change efficacy domains among VAMCs “adopters” defined as delivering Caregivers FIRST within 1 year of the national announcement to those that did not (“non-adopters”). Within “adopters,” we categorized time to adoption based on Rogers’ diffusion of innovation theory including “innovators,” “early adopters,” “early majority,” “late adopters,” and “laggards.” Organizational readiness and site characteristics (facility complexity, staffing levels, volume of applications for caregiver assistance services) were compared between “adopters,” “non-adopters,” and between time to adoption subcategories. Separate logistic regression models were used to assess whether ORIC and site characteristics were associated with early adoption among “adopters.”

Results
Fifty-one of 63 (81%) VAMCs with CSP manager survey respondents adopted Caregivers FIRST during the first year. ORIC change commitment and efficacy were similar for “adopters” and “non-adopters.” However, sites that adopted earlier (innovators and early adopters) had higher ORIC change commitment and efficacy scores than the rest of the “adopters.” Logistic regression results indicated that higher ORIC change commitment (odds ratio [OR] = 2.57; 95% confidence interval [CI], 1.11–5.95) and ORIC change efficacy (OR = 2.60; 95% CI, 1.12–6.03) scores were associated with increased odds that a VAMC was an early adopter (categorized as an “innovator,” “early adopter”, or “early majority”). Site-level characteristics were not associated with Caregivers FIRST early adoption.

Conclusions
To our knowledge, this study is the first to prospectively assess organizational readiness and the timing of subsequent program adoption. Early adoption was associated with higher ORIC change commitment and change efficacy and not site-level characteristics. These findings yield insights into the role of organizational readiness to accelerate program adoption.

Trial registration
ClinicalTrials.gov, NCT03474380. Registered on March 22, 2018
Experiences with a training DSW knowledge model for early-stage researchers
Authors: Devignes Marie-Dominique , Smaïl-Tabbone Malika , Dhondge Hrishikesh , Dolcemascolo Roswitha , Gavaldá-García Jose , Higuera-Rodriguez R. Anahí , Kravchenko Anna , Roca Martínez Joel , Messini Niki , Pérez-Ràfols Anna , Pérez Ropero Guillermo , Sperotto Luca , Chauvot de Beauchêne Isaure , Vranken Wim 
Published: June 2023

Background: Data management is fast becoming an essential part of scientific practice, driven by open science and FAIR (findable, accessible, interoperable, and reusable) data sharing requirements. Whilst data management plans (DMPs) are clear to data management experts and data stewards, understandings of their purpose and creation are often obscure to the producers of the data, which in academic environments are often PhD students. Methods: Within the RNAct EU Horizon 2020 ITN project, we engaged the 10 RNAct early-stage researchers (ESRs) in a training project aimed at formulating a DMP. To do so, we used the Data Stewardship Wizard (DSW) framework and modified the existing Life Sciences Knowledge Model into a simplified version aimed at training young scientists, with computational or experimental backgrounds, in core data management principles. We collected feedback from the ESRs during this exercise. Results: Here, we introduce our new life-sciences training DMP template for young scientists. We report and discuss our experiences as principal investigators (PIs) and ESRs during this project and address the typical difficulties that are encountered in developing and understanding a DMP. Conclusions: We found that the DS-wizard can also be an appropriate tool for DMP training, to get terminology and concepts across to researchers. A full training in addition requires an upstream step to present basic DMP concepts and a downstream step to publish a dataset in a (public) repository. Overall, the DS-Wizard tool was essential for our DMP training and we hope our efforts can be used in other projects.
QUE MATEMÁTICA É PRECISO SABER PARA ENSINAR NA EDUCAÇÃO INFANTIL?
Authors: Tancredi Regina Maria Simões Puccinelli 
Published: June 2023

A formação do professor de Educação Infantil para introduzir as crianças pequenas no universo da matemática escolar é o tema principal desse texto. Ao lado deste, encontra-se, por diretamente relacionados, a aprendizagem da docência e os conhecimentos que os professores precisam adquirir e desenvolver para conseguirem atingir suas metas no ensino. Procura-se uma resposta para a questão do título por seu desmembramento: matemática, ensino e aprendizagem de matemática, saberes e fazeres de professores, crianças pequenas e educação infantil. O texto é fruto de estudos e pesquisas realizadas com e sobre professores, seus conhecimentos e práticas profissionais. Como apoio teórico estão autores que estudaram a temática em seus desdobramentos, tais como Shulman, Nunes e Bryant, Smole, Lorenzato, Kramer, entre outros. Como conclusão, destaca-se a necessidade de uma boa base de conhecimento matemático, associada a uma forma peculiar de conhecer, para que professores da educação infantil possam ter sucesso em sua tarefa de introduzir as crianças pequenas nesse universo. Como decorrência, aborda a complexidade da tarefa de ensinar matemática na educação infantil a partir de propostas educacionais vigentes que levem em conta as características dessa faixa etária. Palavras-chave: Educação infantil; Ensino e aprendizagem de matemática; Saberes de professores; Aprendizagem da docência.
Formação stricto sensu de servidores técnico-administrativos em educação: percepção de gestores e servidores qualificados
Authors: Faria Vinícius Ferreira , Sabino Geruza de Fátima Tomé 
Published: June 2023

O objetivo desta pesquisa foi analisar os desdobramentos para a vida profissional e pessoal dos servidores técnico-administrativos em educação (TAE’s) do Instituto Federal do Norte de Minas Gerais (IFNMG), decorrentes de processos de qualificação em programas de pós-graduação stricto sensu. A análise se deu a partir das percepções de gestores e de servidores qualificados. O aporte teórico abordou teorias de gestão de conhecimentos, gestão por competências e motivação de pessoas, conceitos de eficiência, eficácia e qualidade. Utilizou-se da abordagem qualitativa e descritiva, desenvolvida por meio do Estudo de Caso, apoiado em pesquisas bibliográfica e documental. Aplicaram-se questionários aos participantes do estudo, os quais foram analisados por meio da metodologia de análise de conteúdo. Esta análise possibilitou conhecer o perfil dos servidores qualificados, identificar as principais dificuldades encontradas no processo de qualificação, que estão relacionadas à falta de tempo ou à dificuldade de conciliar trabalho com estudo, especialmente quando não é possível conseguir o afastamento. Como desdobramento para a vida dos servidores, identificou-se diversos fatores, como desenvolvimento pessoal; melhoria nas relações pessoais, nas habilidades e nas atitudes; aumento da autoestima e da autorrealização; e, o fato de o título acadêmico trazer consigo uma importância, não apenas financeira, mas também de status e de realização pessoal e profissional. Por fim, na visão da maioria dos servidores, a formação apresenta-se com muita ou total influência em suas vidas.
RESOLUÇÃO DE PROBLEMAS NAS AULAS DE MATEMÁTICA
Authors: Romanatto Mauro Carlos 
Published: June 2023

Este texto procura mostrar que a metodologia através da resolução de problemas pode ser trabalhada sem grandes rupturas no trabalho docente dos professores que ensinam Matemática. Entretanto, para que isso aconteça, os professores devem, em um primeiro momento, analisar e discutir suas concepções e seus conhecimentos sobre educação, conhecimento matemático, ensino, aprendizagem, avaliação, entre outros elementos presentes no trabalho docente para verificar se são consistentes diante dessa perspectiva de ensinar e de aprender Matemática. Assim, com concepções e conhecimentos coerentes com a metodologia da resolução de problemas, os professores podem enfrentar com sucesso as situações inesperadas e não pensadas que, muitas vezes, ocorrem quando utilizam a resolução de problemas não só como uma metodologia, mas também como uma filosofia de ensino. A experiência do professor como resolvedor de problemas e a reflexão, com especialistas, sobre os resultados de uma aula de Matemática focada na resolução de problemas são condições essenciais para potencializar esse caminho metodológico bastante promissor para a educação matemática. Um problema explorando uma propriedade das frações exemplifica um possível trabalho docente com essa metodologia na busca de tornar o aprendizado matemático significativo para os estudantes. Palavras-chave: Educação matemática; Resolução de problemas; Trabalho docente.