bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distal-continual colon interposition for esophageal reconstruction after esophagectomy: Two case reports
Authors: Guo Bin , He Ming , Zhao Jidong , Ma Minting , Gao Zhanjie 
Published: January 2023

BackgroundColon interposition is a complex and time-consuming procedure requiring at least three or four digestive anastomoses. However, the long-term functional outcomes are promising, with an acceptable operative risk.Case presentationHerein, two cases of esophageal carcinoma that received esophagus reconstruction using the distal continual colon interposition technique have been described. The transverse colon was lifted to the thoracic cavity for the end-to-side anastomosis with the esophagus, and a closure device was used to close the colon instead of severing and isolating the distal end. The duration of the operation was 140 and 150 min, respectively. The blood supply of the colon was maintained during the intervention. The tension-free anastomosis was performed without severe complications, and oral food intake was resumed on postoperative day 6. Neither anastomotic stenosis, antiacid or heartburn, dysphagia, or emptying obstacles nor complaints of diarrhea, bloating, or malodor were reported during the follow-up period.ConclusionsThe modified distal-continual colon interposition technique may have the advantages of a short operation time and potential prevention of serious complications caused by the torsion of mesocolon vessels.
Optimal discharge planning for esophagectomy patients with enhanced recovery after surgery: Recommendations
Authors: Li Kunzhi , Wang Kangning , Wei Xing , Leng Xuefeng , Fang Qiang 
Published: January 2023

BackgroundStudies have suggested that the postoperative length of stay (PLOS) of esophagectomy patients under the enhanced recovery after surgery (ERAS) pathway should be &gt;10 days as against the previously recommended 7 days. We investigated the distribution and influencing factors of PLOS in the ERAS pathway in order to recommend an optimal planned discharge time.MethodsThis was a single-center retrospective study of 449 patients with thoracic esophageal carcinoma who underwent esophagectomy and perioperative ERAS between January 2013 and April 2021. We established a database to prospectively document the causes of delayed discharge.ResultsThe mean and median PLOS were 10.2 days and 8.0 days (range: 5–97), respectively. Patients were divided into four groups: group A (PLOS ≤ 7 days), 179 patients (39.9%); group B (8 ≤ PLOS ≤ 10 days), 152 (33.9%); group C (11 ≤ PLOS ≤ 14 days), 68 (15.1%); group D (PLOS &gt; 14 days), 50 patients (11.1%). The main cause of prolonged PLOS in group B was minor complications (prolonged chest drainage, pulmonary infection, recurrent laryngeal nerve injury). Severely prolonged PLOS in groups C and D were due to major complications and comorbidities. On multivariable logistic regression analysis, open surgery, surgical duration &gt;240 min, age &gt;64 years, surgical complication grade &gt;2, and critical comorbidities were identified as risk factors for delayed discharge.ConclusionsThe optimal planned discharge time for patients undergoing esophagectomy with ERAS should be 7–10 days with a 4-day discharge observation window. Patients at risk of delayed discharge should be managed adopting PLOS prediction.
Pharmacokinetic and pharmacodynamic properties of pantoprazole in calves
Authors: Olivarez Jeff D. , Mulon Pierre-Yves , Ebner Lisa S. , Cremerius Haley , Cantrell Channing , Rahn Rebecca , Soto-Gonzalez Windy , Bergman Joan , Cox Sherry , Mochel Jonathan P. , Kreuder Amanda J. , Smith Joe S. 
Published: January 2023

IntroductionDevelopment of abomasal ulceration is a large concern, especially within calves; however, there is a paucity of research into the use of gastro protectants in ruminant species. Proton pump inhibitors, such as pantoprazole, are widely used in humans and companion animals. Their efficacy in ruminant species is undetermined. The objectives of this study were to 1) estimate the plasma pharmacokinetic parameters for pantoprazole in neonatal calves after three days of intravenous (IV) or subcutaneous (SC) administration, and 2) measure the effect pantoprazole had on abomasal pH over the treatment period.MethodsPantoprazole was administered to 6 Holstein-Angus cross bull calves at a dose of 1 mg/kg (IV) or 2 mg/kg (SC), once a day (every 24 h) for three days. Plasma samples were collected over a 72 h period and analyzed via HPLC-UV for determining pantoprazole concentrations. Pharmacokinetic parameters were derived via non-compartmental analysis. Abomasal (n= 8) samples were collected via abomasal cannulas over a 12 h period, per calf per day. Abomasal pH was determined via a bench top pH analyzer.ResultsFollowing Day 1 of IV administration, plasma clearance, elimination half-life, and volume of distribution of pantoprazole were estimated at 199.9 mL/kg/h, 1.44 h, and 0.51 L/kg, respectively. On Day 3 of IV administration, the reported values were 192.9 mL/kg/h, 2.52 h, and 1.80 L/kg mL, respectively. Elimination half-life and volume of distribution (V/F) of pantoprazole following SC administration were estimated at 1.81 h and 0.55 L/kg, respectively, on Day 1; and 2.99 h and 2.82 L/kg, respectively, on Day 3.DiscussionThe reported values for IV administration were similar to those previously reported in calves. SC administration appears to be well absorbed and tolerated. The sulfone metabolite was detectable for 36 h after the last administration for both routes. Abomasal pH was significantly higher than the pre-pantoprazole pH 4, 6, and 8 h after administration in both the IV and SC groups. Further studies of pantoprazole as a treatment/preventative for abomasal ulcers are warranted.
Characterization and epidemiology of antimicrobial resistance patterns of Salmonella spp. and Staphylococcus spp. in free-ranging rhesus macaque (Macaca mulatta) at high-risk interfaces with people and livestock in Bangladesh
Authors: Rahman Md. Kaisar , Hassan Mohammad Mahmudul , Islam Shariful , Rostal Melinda K. , Uddin Md. Helal , Hagan Emily , Samad Mohammed Abdus , Flora Meerjady Sabrina , Epstein Jonathan H. , Islam Ariful 
Published: January 2023

IntroductionAntimicrobial resistance (AMR) is a growing global health threat for humans and animals. Environmental contamination of antimicrobials from human and domestic animal feces has been linked to AMR in wildlife populations, including rhesus macaques. This study aimed to describe the eco-epidemiology of AMR within Salmonella and Staphylococcus species isolated from rhesus macaques.MethodsWe followed macaque groups for 4 h per day (2 days) to observe the direct and indirect contact rate and type between macaques and people and livestock. We collected 399 freshly defecated, non-invasive fecal samples from macaques at seven sites in Bangladesh in January–June 2017. Bacterial isolation and identification were conducted using culture, biochemical characteristics, and polymerase chain reaction (PCR). An antimicrobial susceptibility test (AST) for 12 antimicrobials for each organism was conducted using the Kirby–Bauer disc diffusion method.ResultsThe overall prevalence of Salmonella spp. and Staphylococcus spp. in rhesus macaques was 5% (n = 18; 95% CI: 3–7%) and 16% (n = 64; 95% CI: 13–20%), respectively. All the isolated Salmonella spp. and most of the Staphylococcus spp. (95%; 61/64; 95% CI: 86.9–99%) were resistant to at least one antimicrobial. The odds of a fecal sample having antimicrobial-resistant Salmonella spp (OR = 6.6; CI: 0.9–45.8, P = 0.05) and Staphylococcus spp. (OR = 5.6; CI: 1.2–26, P = 0.02) were significantly higher in samples collected at peri-urban sites than those collected at rural and urban sites. Salmonella spp. were most frequently resistant to tetracycline (89%), azithromycin (83%), sulfamethoxazole-trimethoprim (50%), and nalidixic acid (44%). Staphylococcus spp. were found to be highly resistant to ampicillin (93%), methicillin (31%), clindamycin (26%), and rifampicin (18%). Both bacterial species produced colonies with multidrug resistance to up to seven antimicrobials. Direct and indirect contact rates (within 20 m for at least 15 min) and resource sharing between macaques and people were higher in urban sites, while macaque-livestock contact rates were higher in rural sites.DiscussionThe study shows that resistant microorganisms are circulating in rhesus macaque, and direct and indirect contact with humans and livestock might expand the resistant organisms.
Patients With Systemic Reaction to Their Hernia Mesh: An Introduction to Mesh Implant Illness
Authors: Fadaee Negin , Huynh Desmond , Khanmohammed Zayan , Mazer Laura , Capati Isabel , Towfigh Shirin 
Published: January 2023

In our practice, we have noticed an increased number of patients requiring mesh removal due to a systemic reaction to their implant. We present our experience in diagnosing and treating a subpopulation of patients who require mesh removal due to a possible mesh implant illness (MII). All patients who underwent mesh removal for indication of mesh reaction were captured from a hernia database. Data extraction focused on the patients’ predisposing medical conditions, presenting symptoms suggestive of mesh implant illness, types of implants to which reaction occurred, and postoperative outcome after mesh removal. Over almost 7 years, 165 patients had mesh removed. Indication for mesh removal was probable MII in 28 (17%). Most were in females (60%), average age was 46 years, with average pre-operative pain score 5.4/10. All patients underwent complete mesh removal. Sixteen (57%) required tissue repair of their hernia; 4 (14%) had hybrid mesh implanted. Nineteen (68%) had improvement and/or resolution of their MII symptoms within the first month after removal. We present insight into a unique but rising incidence of patients who suffer from systemic reaction following mesh implantation. Predisposing factors include female sex, history of autoimmune disorder, and multiple medical and environmental allergies and sensitivities. Presenting symptoms included spontaneous rashes, erythema and edema over the area of implant, arthralgia, headaches, and chronic fatigue. Long-term follow up after mesh removal confirmed resolution of symptoms after mesh removal. We hope this provides greater attention to patients who present with vague, non-specific but debilitating symptoms after mesh implantation.
Kimchi and Leuconostoc mesenteroides DRC 1506 Alleviate Dextran Sulfate Sodium (DSS)-Induced Colitis via Attenuating Inflammatory Responses
Authors: Moon Hye-Jung , Oh Suk-Heung , Park Ki-Bum , Cha Youn-Soo 
Published: January 2023

Ulcerative colitis (UC) is caused by inflammation only in the mucosa of the colon, and its incidence is increasing worldwide. The intake of probiotics is known to have a beneficial effect on the development of UC. In this study, we investigated the alleviating effects of kimchi (KC), a fermented food rich in probiotics, and Leuconostoc mesenteroides DRC 1506 (DRC) isolated from kimchi on UC. A freeze-dried kimchi suspension and DRC were orally given to mice at a dose of 1 × 109 CFU/day for 3 weeks. Furthermore, 3% dextran sulfate sodium (DSS) in drinking water was given to induce UC. The KC and DRC groups reduced symptoms of colitis, such as disease activity index, decrease in colon length, colon weight-to-length ratio, and pathological damage to the colon caused by DSS treatment. The KC and DRC groups decreased the levels of pro-inflammatory cytokine (TNF-α) and increased anti-inflammatory cytokine (IL-10) in the colon tissues. At the mRNA and protein expression levels in the colon tissue, KC and DRC groups downregulated inflammatory factors and upregulated tight junction-related factors. Therefore, DRC, as well as KC supplementation, are potent in alleviating UC by improving the inflammatory response and mucosal barrier function in the colon.
Towards Moving Objects Behavior Analysis: Region Speed Limit Rate Measure
Authors: Moreno Arboleda Francisco Javier , Garani Georgia , Zea Gallego Simon 
Published: January 2023

In this paper, a measure is proposed that, based on the trajectories of moving objects, computes the speed limit rate in each of the cells in which a region is segmented (the space where the objects move). The time is also segmented into intervals. In this way, the behavior of moving objects can be analyzed with regard to their speed in a cell for a given time interval. An implementation of the corresponding algorithm for this measure and several experiments were conducted with the trajectories of taxis in Porto (Portugal). The results showed that the speed limit rate measure can be helpful for detecting patterns of movement, e.g., in a day (morning hours vs. night hours) or on different days of the week (weekdays vs. weekends). This measure might also serve as a rough estimate for congestion in a (sub)region. This may be useful for traffic analysis, including traffic prediction.
DESIGN FEATURES OF BALLAST TYPE FOUNDATIONS FOR TOWER STRUCTURES
Authors: Токарева Л. А. , Стрелков Ю. М. , Сабитов Л. С. , Хусаинов Р. Д. 
Published: January 2023

Башенные конструкции в настоящее время получили широкое применение в качестве конструкций рекламного, коммуникационного и энергетического назначения. В связи с этим встает вопрос об определении и выборе конструкции с наилучшей несущей способностью, которая при этом будет обладать параметрами, актуальными для потребителя, - эстетические свойства, простота монтажа в сопоставлении с традиционными подходами к конструированию. Также одним из важнейших вопросов является ограничение на места установки башенных конструкций ввиду запрета их расположения в зонах массового нахождения людей, в местах расположения коммуникаций. Необходимость установки башенных конструкций в условиях указанных ограничений привела к возникновению новых конструктивных решений фундаментов, а именно - фундаменты балластного типа, устанавливаемые на поверхность земли без ограничений на установленное время. В данной статье приведен анализ существующих фундаментов балластного типа, предназначенных для сооружений башенного типа.
Tower structures are currently widely used as structures for advertising, communication and energy purposes. In connection with this, the question arises of determining and choosing a structure with the best load-bearing capacity, which at the same time will have parameters that are relevant to the consumer - aesthetic properties, ease of installation in comparison with traditional design approaches. Also, one of the most important issues is the restriction on the installation sites of tower structures in view of the prohibition of their location in areas of mass presence of people, in the locations of communications. The need to install rack structures under the conditions of these restrictions has led to the emergence of new design solutions for foundations, namely, ballast-type foundations installed on the surface of the earth without restrictions for a set time. This article provides an analysis of existing ballast-type foundations intended for tower-type structures.
CONFIDENTIAL COMPUTINGIN A PROTECTED COMPUTING ENVIRONMENT
Authors: Румянцев К. Е. , Хаджиева Л. К. 
Published: January 2023

Обеспечение информационной безопасности является немаловажным фактором в настоящее время, особенно это касается вычислительных систем, инфокоммуникационных систем и систем передачи данных. В статье рассмотрена надежность вычислений, изложена концепция вычислений, проведена параллель между физической и логической составляющей защиты информации. Применению больших данных и технологий искусственного интеллекта в наше время уделяется все больше внимания с точки зрения защиты конфиденциальности и адекватного соответствия данных. Методы, которые могут обеспечить безопасность данных и использовать данные для доверенных вычислений в соответствии с требованиями, так называемые конфиденциальные вычисления, привлекают все больше и больше внимания людей. Решение данной проблемы в статье предлагается реализовать с применением технологии TEMPEST, которая применяет экранирование, которое ограничивает утечку электромагнитной информации от внутреннего излучения, предотвращает попадание внешних радиочастотных помех в вычислительные среды.
Ensuring information security is no small important factor at present, especially for computing systems, infocommunication systems and data transmission systems. Since electromagnetic leakage not only harms the health of people who are near the computer, but also causes electromagnetic interference in the surrounding electronic equipment and leads to information leakage, this article discusses methods for protecting information and preventing leakage of electromagnetic radiation, analyzes methods for protecting information and their applications. The TEMPEST shielding technology, which includes the mechanism of electromagnetic leakage of information processing equipment, is considered. In addition to electromagnetic information leakage, the article considers the reliability of calculations, outlines the concept of calculations, draws a parallel between the physical and logical components of information protection.
DESCRIPTION REPRESENTATION OF 3D OBJECTS FOR THEIR IDENTIFICATION IN THE INFORMATION SEARCH SUBSYSTEM OF ERP-SYSTEMS
Authors: Аликов А.Ю. , Калиниченко А.В. 
Published: January 2023

Глобальные дескрипторы позволяют описывать форму всей поверхности 3D-модели и, как правило, используются для сравнения 3D-моделей друг с другом. В настоящей работе рассматривается возможность применения дескриптивного представления 3D-объектов для их идентификации в подсистеме информационного поиска в составе автоматизированной системы управления предприятием с целью «грубого» отсеивания заведомо отличающихся 3D-объектов, тем самым уменьшая объем входных данных, к которым в дальнейшем будут применены более точные и ресурсозатратные алгоритмы, что позволит увеличить скорость идентификации 3D-объектов без снижения точности.
Global descriptors allow you to describe the shape of the entire surface of a 3D model and are typically used to compare 3D models with each other. In this article, we consider the possibility of using a descriptive representation of 3D objects for their identification in the information retrieval subsystem as part of an automated control system for the purpose of “rough” sifting out obviously different 3D objects, thereby reducing the amount of input data, to which more accurate and resource-intensive algorithms will be applied in the future, which will increase the speed of identification of 3D objects without reducing accuracy.
ALRFLI-ACTIVATED SLAG CONCRETE WITH RUBBER CRAMB FROM TIRES FOR TRANSPORT CONSTRATION
Authors: Смирнова О. М. , Казанская Л. Ф. 
Published: January 2023

Разработаны новые композиты гидратационного твердения и технология переработки вторичных ресурсов при использовании фракционированной резиновой крошки из изношенных автошин с установленной фракцией. Проанализированы требования к изделиям и конструкциям, применяемым в дорожном строительстве. Использование фракционированной, резиновой крошки позволяет изменять пористость композита и за счет этого повышать звукопоглощающие свойства, ударную прочность. Получена диаграмма деформирования в осях «нагрузка-прогиб» для образцов с резиновой крошкой. Установлено, что при использовании резиновой крошки в составе шлакощелочного бетона изменяется характер разрушения, отсутствует хрупкое разрушение, возрастает удельная работа разрушения. Предел прочности при сжатии и изгибе снижается при использовании резиновой крошки. Однако увеличение удельной работы разрушения позволяет рассматривать разработанный композит для применения в деформируемых конструкциях.
New hydration hardening composites and technology for recycling secondary resources using fractionated rubber chips from worn tires with a fixed fraction have been developed. The requirements for products and structures used in road construction are analyzed. The use of fractionated rubber chips makes possible to change the porosity of the composite and thereby increase the sound-absorbing properties, impact strength. It is stated that by changing the type and consumption of the binder, as well as the consumption of rubber crumbs, it is possible to change the properties of the composite in a wide range: compressive and tensile strength, impact strength, sound absorption coefficient. In addition to fractionated rubber crumbs, the micro- and nanoporosity of the cementing matrix can be regulated by the use of mineral additives with a developed system of micro- and nanopores. The presented results contribute to the development of an ecological approach to making design decisions in construction.
BIG DATA SECURITY ANALYSIS IN IOT AND METHODS FOR OVERCOMING THEM
Authors: Пашаев М. Я. , Абдулаева С. И. , Намаева М. М. , Халиева Х. С. 
Published: January 2023

Объем обмена данными в сети увеличивается за счет расширения пространства Интернета вещей и его все большей популярности в последние годы. В связи с ростом запросов на подключение к сети и использование сетевых технологий многократно возросла необходимость сохранения конфиденциальности и безопасности личных данных. В рассматриваемой проблемной плоскости пользователи сети, которые являются датчиками, также масштабно увеличивают объем обрабатываемых данных. В результате перед комплексом технического обеспечения - маршрутизаторы сети и сетевые серверы - ставятся серьезные задачи по контролю и обеспечению безопасности такого объема данных. Предлагаемая статья приводит анализ этих проблем, направленный на обеспечение безопасности пользователей и представление процедур, позволяющих решать проблемы и выражать стратегии их преодоления. Предлагаются некоторые методы использования функциональности корректного шифрования, в том числе и формирования безопасного протокола. Другой способ преодоления проблем с конфиденциальностью больших данных - это продуманный дизайн протокола связи.
The volume of data exchange in this network is increasing due to the expansion of the Internet of Things and its increasing prominence in recent years. With increasing requests to connect to the network and use its services, the need to maintain privacy and security is felt like never before, and it has all become a challenge. Keeping users safe on smaller networks seems easier and threats more predictable. Because network users who are sensors also increase the amount of data. As a result, network routers and network servers have become a major challenge in controlling and securing this amount of data. We analyze these issues in this article. This document aims to ensure the safety of users and to provide procedures for solving problems and expressing coping strategies. Some methods are suggested, such as the use of an encryption function and a secure protocol. Another way to overcome problems with big data is through thoughtful design of the communication protocol. Finally, we point out some of the existing problems associated with big data in the Internet of Things.