bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tobacco smoking and vascular biology and function: evidence from human studies
Authors: Hahad Omar , Kuntic Marin , Kuntic Ivana , Daiber Andreas , Münzel Thomas 
Published: March 2023

AbstractTobacco cigarette smoking is among the most complex and least understood health risk factors. A deeper insight into the pathophysiological actions of smoking exposure is of special importance as smoking is a major cause of chronic non-communicable diseases, in particular of cardiovascular disease as well as risk factors such as atherosclerosis and arterial hypertension. It is well known that smoking exerts its negative effects on cardiovascular health through various interdependent pathophysiological actions including hemodynamic and autonomic alterations, oxidative stress, inflammation, endothelial dysfunction, thrombosis, and hyperlipidemia. Importantly, impaired vascular endothelial function is acknowledged as an early key event in the initiation and progression of smoking-induced atherosclerosis. Increasing evidence from human studies indicates that cigarette smoke exposure associates with a pathological state of the vascular endothelium mainly characterized by reduced vascular nitric oxide bioavailability due to increased vascular superoxide production. In the present overview, we provide compact evidence on the effects of tobacco cigarette smoke exposure on vascular biology and function in humans centered on main drivers of adverse cardiovascular effects including endothelial dysfunction, inflammation, and oxidative stress.
Effect of psychosocial stress and coping strategies on non-surgical periodontal therapy in patients with generalized stage III/IV periodontitis: a longitudinal intervention study
Authors: Romano Federica , Bebars Ahmad , Ortu Valentina , Bottone Michele , Giraudi Marta , Mariani Giulia Maria , Baima Giacomo , Aimetti Mario 
Published: March 2023

Abstract
Objectives
The aim of this longitudinal intervention study was to assess the impact of psychosocial stress and coping response strategies on the clinical outcomes in periodontitis patients treated with non-surgical periodontal therapy (NSPT).

Materials and methods
After the administration of psychological questionnaires, patients diagnosed with generalized stage III–IV periodontitis were categorized into different groups depending on their stress levels (10-item perceived stress level (PSS-10)) and coping response strategies (coping responses inventory (CRI)). Clinical data were collected 1 week before and 3 months after the completion of NSPT.

Results
Of the 90 patients included at baseline, 27 presented major and 63 minor stress levels, while 40 had avoidance and 50 approach coping behavior. All clinical parameters were similar at the baseline across different categories. At re-evaluation, full-mouth bleeding score (FMBS), mean probing pocket depth (PPD), and number of residual pathological pockets were significantly superior in groups with higher stress levels (p <0.001, p =0.001, and p =0.020, respectively), while higher full-mouth plaque scores (FMPS) and FMBS were found in patients with avoidance coping strategies (p =0.009 and p <0.001, respectively). When jointly evaluated, an added detrimental effect of coping styles on allostatic load was observed. Multivariate analysis confirmed a significant effect of stress levels and coping strategies on final FMBS, but not of coping on mean PPD.

Conclusion
Psychosocial stress and avoidance coping strategy seem to negatively influence the clinical outcomes of NSPT at short term (NCT04739475; 9/1/2017).

Practical implications
Based on these findings, patients reflecting these psychological profiles should be considered at greater risk for poor NSPT response and may benefit from complementary stress management strategies.
Effects of Nystatin oral rinse on oral Candida species and Streptococcus mutans among healthy adults
Authors: Aljaffary Mohammed , Jang Hoonji , Alomeir Nora , Zeng Yan , Alkhars Naemah , Vasani Shruti , Almulhim Abdullah , Wu Tong Tong , Quataert Sally , Bruno Jennifer , Lee Aaron , Xiao Jin 
Published: March 2023

Abstract

Objectives
To examine the effect of Nystatin oral rinse on oral Candida species and Streptococcus mutans carriage.

Materials and methods
Twenty healthy adults with oral candidiasis participated in the single-arm clinical trial and received Nystatin oral rinse for 7 days, 4 applications/day, and 600,000 International Units/application. Demographic-socioeconomic-oral-medical conditions were obtained. Salivary and plaque Candida species and Streptococcus mutans were assessed at baseline and 1-week and 3-month follow-ups. Twenty-four salivary cytokines were assessed. Candida albicans isolates underwent Nystatin susceptibility test.

Results
Half of participants (10/20) were free of salivary C. albicans after using Nystatin rinse. Salivary S. mutans was significantly reduced at 3-month follow-up (p < 0.05). Periodontal status reflected by bleeding-on-probing was significantly improved at 1-week and 3-month follow-ups (p < 0.05). Plaque accumulation was significantly reduced at 1-week follow-up (p < 0.05). Interestingly, the responses to Nystatin oral rinse were not associated with race, gender, age, oral hygiene practice, adherence to Nystatin rinse, or sweet consumption (p > 0.05). No C. albicans isolates were resistant to Nystatin. Furthermore, salivary cytokine eotaxin and fractalkine were significantly reduced at 3-month follow-up among participants who responded to Nystatin rinse (p < 0.05).

Conclusions
The study results indicate that oral antifungal treatment had an effect on S. mutans salivary carriage. Future clinical trials are warranted to comprehensively assess the impact of antifungal treatment on the oral flora other than S. mutans and Candida.

Clinical relevance
Due to the potential cariogenic role of oral Candida species, antifungal approaches shed new light on the prevention and management of dental caries from a fungal perspective.
Hierarchical Integration of Model Predictive and Fuzzy Logic Control for Combined Coverage and Target-Oriented Search-and-Rescue via Robots with Imperfect Sensors
Authors: de Koning Christopher , Jamshidnejad Anahita 
Published: March 2023

AbstractSearch-and-rescue (SaR) in unknown environments is a crucial task with life-threatening risks. SaR requires precise, optimal, and fast decisions to be made. Robots are promising candidates expected to execute various SaR tasks autonomously. While humans use heuristics to effectively deal with uncertainties of SaR, optimisation of multiple objectives (e.g., the mission time, the area covered, the number of victims detected), in the presence of physical and control constraints, is a mathematical challenge that requires machine computations. Thus including both human-inspired and mathematical capabilities in decision making of SaR robots is highly desired. However, developing control approaches that exhibit both capabilities has been significantly ignored in literature. Moreover, coordinating the decisions of the robots in large-scale SaR missions with affordable computation costs is an open challenge. Finally, in real-life, due to defects (e.g., in the sensors of the robots) or environmental factors (e.g., smoke) data perceived by SaR robots may be prone to uncertainties. We introduce a hierarchical multi-agent control architecture that simultaneously provides the following advantages: exploiting non-homogeneous and imperfect perception capabilities of SaR robots; improving the global performance as it is provided by centralised controllers; computational efficiency and robustness to failure of the central controller as offered by decentralised control methods. The integrated structure of the proposed control framework allows to combine human-inspired and mathematical decision making methods, via respectively fuzzy logic and model predictive control, in a coordinated and computationally efficient way. Our results for various computer-based simulations show that while the area coverage with the proposed control approach is comparable to existing heuristic methods that are particularly developed for coverage-oriented SaR, our approach has a significantly better performance regarding locating the trapped victims. Furthermore, with comparable computation times, the proposed control approach successfully avoids conflicts that may appear in non-cooperative control methods. In summary, the proposed multi-agent control system is capable of combining coverage-oriented and target-oriented SaR in a balanced and coordinated way.
Youth Suicide and Self-Harm: Latent Class Profiles of Adversity and the Moderating Roles of Perceived Support and Sense of Safety
Authors: Silke Charlotte , Brady Bernadine , Devaney Carmel , O’Brien Cliodhna , Durcan Micheal , Bunting Brendan , Heary Caroline 
Published: March 2023

AbstractResearch suggests that exposure to adversity can lead to an increased risk of experiencing suicidal and self-injurious thoughts or behaviours, but few studies have examined whether different patterns of adversity are differentially associated with youth suicide/self-harm. The current study aims to explore the relationship between exposure to adversity across various social domains and youth self-harm and suicidality, using a person centred approach, and examines whether access to social support and a sense of safety across home, peer or school settings buffer the relationship between adversity and self-harm/suicidality. Secondary data analyses were carried out on cross-sectional self-report data collected from 4848 (Mage=15.78, SD = 0.59; 50% female) adolescents who participated in the Irish Planet Youth survey. Latent Class Analyses identified four distinct profiles of adversity; low-adversity (n = 2043, 42%); peer-adversity (n = 972, 20%); parental-adversity (n = 1189, 25%); and multiple-adversity (n = 644, 13%). Findings from logistic moderated regressions indicated that there were significant differences in self-harm and suicidality across the adversity classes. Although parental support and perceived safety at school were negatively associated with suicidality and self-harm outcomes, no significant moderation effects were observed. These findings suggest that youth who experience adversity across multiple social domains are more likely to report suicidal and self-harm thoughts and behaviours, and should be key targets for intervention/prevention efforts. While parental support and school safety may act as significant compensatory factors, further work is needed to identify the social resources that can offset the risk imposed by youth’s adverse experiences.
Stability and Change in Adolescents’ Sense of Agency: Contributions of Sex, Multiple Risk, Pandemic Stress, and Attachment to Parents
Authors: Nunes Filipa , Mota Catarina P. , Ferreira Tiago , Schoon Ingrid , Matos Paula M. 
Published: March 2023

AbstractAlthough literature states that individual, relational, and contextual factors contribute to adolescents’ sense of agency, more research is needed to clarify and understand how adolescents develop this belief over time. The current study examined the stability/change trajectories of the sense of agency during adolescence, specifically across high school, analyzing whether attachment to parents over time, adolescents’ sex, cumulative risk in baseline, and pandemic-related stress explained these trajectories. The sample included 467 Portuguese adolescents (40.7% were males; Mage = 15.58 years, SD = 0.80), evaluated three times across 18 months. This work yielded three significant findings. First, adolescents’ sense of agency significantly increased over time, with significant between-subject variance at the initial levels but not at the growth rate. Second, attachment to parents consistently links to adolescents’ sense of agency across time, despite the differential contributions from attachment to mothers and fathers. Third, boys reported greater growth in the sense of agency than girls. Adolescents’ cumulative risk at T1 predicted lower initial levels of sense of agency, whereas higher pandemic-related stress predicted less growth of the sense of agency. These findings emphasize the contributions of individual and family characteristics and the role of the broader social context in shaping the development of adolescents’ sense of agency. The findings underline the need to consider further the differential influences of adolescents’ relationships with mothers and fathers to understand changes in adolescents’ sense of agency.
Structural resilience and recovery of a criminal network after disruption: a simulation study
Authors: Diviák Tomáš 
Published: March 2023

Abstract
Objectives
Criminal networks tend to recover after a disruption, and this recovery may trigger negative unintended consequences by strengthening network cohesion. This study uses a real-world street gang network as a basis for simulating the effect of disruption and subsequent recovery on network structure.

Methods
This study utilises cohesion and centrality measures to describe the network and to simulate nine network disruptions. Stationary stochastic actor-oriented models are used to identify relational mechanisms in this network and subsequently to simulate network recovery in five scenarios.

Results
Removing the most central and the highest-ranking actors have the largest immediate impact on the network. In the long-term recovery simulation, networks become more compact (substantially so when increasing triadic closure), while the structure disintegrates when preferential attachment decreases.

Conclusion
These results indicate that the mechanisms driving network recovery are more important than the immediate impact of disruption due to network recovery.
Aberrations in the early pregnancy serum metabolic profile in women with prediabetes at two years postpartum
Authors: Muhli Ella , Benchraka Chouaib , Lotankar Mrunalini , Houttu Noora , Niinikoski Harri , Lahti Leo , Laitinen Kirsi 
Published: March 2023

Abstract
Introduction
Aberrations in circulating metabolites have been associated with diabetes and cardiovascular risk.

Objectives
To investigate if early and late pregnancy serum metabolomic profiles differ in women who develop prediabetes by two years postpartum compared to those who remain normoglycemic.

Methods
An NMR metabolomics platform was used to measure 228 serum metabolite variables from women with pre-pregnancy overweight in early and late pregnancy. Co-abundant groups of metabolites were compared between the women who were (n = 40) or were not (n = 138) prediabetic at two years postpartum. Random Forests classifiers, based on the metabolic profiles, were used to predict the prediabetes status, and correlations of the metabolites to glycemic traits (fasting glucose and insulin, HOMA2-IR and HbA1c) and hsCRP at postpartum were evaluated.

Results
Women with prediabetes had higher concentrations of small HDL particles, total lipids in small HDL, phospholipids in small HDL and free cholesterol in small HDL in early pregnancy (p = 0.029; adj with pre-pregnancy BMI p = 0.094). The small HDL related metabolites also correlated positively with markers of insulin resistance at postpartum. Similar associations were not detected for metabolites in late pregnancy. A Random Forests classifier based on serum metabolites and clinical variables in early pregnancy displayed an acceptable predictive power for the prediabetes status at postpartum (AUROC 0.668).

Conclusion
Elevated serum concentrations of small HDL particles in early pregnancy associate with prediabetes and insulin resistance at two years postpartum. The serum metabolic profile during pregnancy might be used to identify women at increased risk for type 2 diabetes.
Testing the environmental Kuznets curve hypothesis in terms of ecological footprint and CO2 emissions through energy diversification for Turkey
Authors: Acaroğlu Hakan , Kartal Hatice Melissa , García Márquez Fausto Pedro 
Published: March 2023

AbstractThis research work analyzes the relationship between environmental degradation, economic growth, trade openness, primary energy consumption, coal consumption, and hydroelectricity consumption in Turkey from 1971 to 2015 using the autoregressive distributed lag (ARDL) time series approach through the hypothesis of the environmental Kuznets curve (EKC). Carbon dioxide (CO2) emissions and ecological footprint are both used as indicators of environmental degradation, which employs six different models. According to the results found in this study, while trade openness increases CO2 emissions, it decreases ecological footprint in the long-run. Coal consumption raises both CO2 emissions and ecological footprint. While hydroelectric energy reduces CO2 emissions, it has no effect on the environment. The results demonstrate that the EKC hypothesis is correct for both CO2 emissions and Turkey’s ecological footprint. The threshold points are investigated as $18,704, $16,361, and $13,571 in models, where CO2 emissions are the dependent variable. In models where the ecological footprint is the dependent variable, the investigated threshold points of $11,824, $11,821, and $15,476 are higher than the gross domestic product (GDP) per capita during the analysis periods. Furthermore, the findings highlight the importance of renewable energy use in reducing environmental degradation and coal use in increasing environmental degradation. These findings can shed light on the importance of transition to renewable energy sources (i.e., hydroelectricity consumption), from fossil fuels (i.e., coal consumption), related to future planning in energy diversification for Turkey.
Prevalence and Correlates of Panic Attacks Among People Who Primarily Smoke Methamphetamine
Authors: Hine Rochelle , Ward Bernadette , Kippen Rebecca , Sutton Keith , Duncan Zoe , Quinn Brendan , Powell Aimee , Dietze Paul 
Published: March 2023

Abstract
Few studies have examined panic attacks and social and demographic factors, amongst people who use methamphetamine. This study explores the prevalence and correlates of panic attacks amongst an Australian sample of 711 people who primarily smoke methamphetamine. Baseline data for this study was gathered from participants recruited from regional and metropolitan communities across Victoria, Australia, in an ongoing prospective cohort study. Sequential logistic regression was used to examine correlations between panic attacks and sociodemographic, mental health and methamphetamine use variables. Over one-third (36%) of participants reported experiencing a recent panic attack (within the last 4 weeks). The following characteristics were associated with an increased likelihood of panic attacks: being female [aOR 1.85, 95% CI 1.25, 2.60], younger (18–29 years) [aOR 1.82, 95% CI 1.16, 2.85], non-heterosexual [aOR 2.19, 95% CI 1.37, 3.49], having experienced interpersonal assault in the past 12 months [aOR 1.71, 95% CI 1.19, 2.45], being methamphetamine-dependent [aOR 1.78, 95% CI 1.22, 2.59] and reporting moderate to severe symptoms of anxiety [aOR 5.49, 95% CI 3.93, 7.69] and depression [aOR 3.98, 95% CI 2.86, 5.53]. Opportunities exist for health services to proactively engage and support this population when they present in distressed states, with a non-judgemental, trauma-informed approach.

Highlights
• It is estimated that over one third of people who smoke methamphetamine experience panic attacks.
• Methamphetamine smokers who are young, female and non-heterosexual are at increased risk of experiencing panic attacks.
• Presentations during mental distress are an opportunity for psychoeducation and harm reduction discussions.
Dissecting entrepreneurial team research: a bibliometric analysis
Authors: Horvatinovic Tin , Mikic Mihaela , Dabić Marina 
Published: March 2023

AbstractDespite the massive volume of published articles, the pool of knowledge on entrepreneurial teams needs to be algorithmically classified and meticulously scrutinised. It is crucial for the field to be historically positioned under relevant themes, internally connected in terms of conceptual foundations, and systematically categorised in consonance with previously utilised frameworks of analysis. These concerns are resolved in this study by conducting a bibliometric analysis of 672 relevant articles. This form of analysis has not been previously employed on the topic of entrepreneurial teams. First, this study identifies eight main thematic clusters in the entrepreneurial teams field and their sub-themes. The eight main thematic clusters are: (i) Intellectual Capital, (ii) Cognition and Behaviour, (iii) Science and Technology, (iv) Finance, (v) Transformation, (vi) Internationalisation, (vii) Family, and (viii) Community and Surroundings. Second, the study reveals the clusters most needing restoration, relations between clusters, and input-mediator-output variables by their respective cluster. In addition, an implied scholarly depiction of entrepreneurial teams is articulated, which can serve as a basis for developing an entrepreneurial teams theory. Finally, promising avenues for future research are suggested for the entire field and every cluster specifically.
Bounds for theta sums in higher rank. I
Authors: Marklof Jens , Welsh Matthew 
Published: March 2023

AbstractTheta sums are finite exponential sums with a quadratic form in the oscillatory phase. This paper establishes new upper bounds for theta sums in the case of smooth and box truncations. This generalises a classic 1977 result of Fiedler, Jurkat and Körner for one-variable theta sums and, in the multi-variable case, improves previous estimates obtained by Cosentino and Flaminio in 2015. Key steps in our approach are the automorphic representation of theta functions and their growth in the cusps of the underlying homogeneous space.
Happy storytelling promotes emotional contagion and interpersonal closeness
Authors: Wei Yanqiu , Zhang Ling , Lian Tao , Chen Ying , Liao Sihua , Guo Qi , Hu Ping 
Published: March 2023

Abstract
Storytelling is an important part of human’s daily life. It is a powerful means to share emotions with others. Thus, individuals’ autobiographical memory is a suitable carrier of intentional emotional contagion. Few researchers have explored intentional emotional contagion using individuals’ autobiographical memory, especially people’s neural responses to individuals’ autobiographical memory, and the corresponding mental mechanism of emotional contagion has not been sufficiently clarified. This study investigated the intentional emotional contagion in people’s daily conversation using a functional near-infrared spectroscopy technique comprising two phases. The first phase involved speakers’ video production. In the second phase, the videos were presented to the listeners, during which we obtained listeners’ brain activities while they viewed the videos. The behavioral results showed that compared with the outcome from neutral stories, the degree of emotional contagion induced by happy stories and the degree of overlap between the speaker and the listener were larger. The brain results demonstrated that neutral stories induced greater activation than happy stories in channel 11 and channel 15. These results suggest that to be a happy girl is quite easy and sharing happiness promotes closeness. Future research directions are also provided.