bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recurrent malignant peritoneal mesothelioma treated by a second resection: A case report
Authors: Miyata Takashi , Nishiki Hisashi , Shinden Yuki , Motoyama Shota , Sannomiya Yuta , Tamezawa Hozumi , Nagayama Taigo , Kin Ryosuke , Hashimoto Akifumi , Kaida Daisuke , Tomita Yasuto , Nakamura Naohiko , Miyashita Tomoharu , Fujita Hideto , Ueda Nobuhiko , Takamura Hiroyuki 
Published: May 2023

Key Clinical MessageMalignant peritoneal mesothelioma, a rare and poor prognosis disease, is seldom treated surgically, especially for recurrence. However, early diagnosis and aggressive treatment of primary and recurrent tumors can achieve long‐term patient survival.AbstractMalignant peritoneal mesothelioma (MPM) is a rare and aggressive tumor, and rarely indicated for surgery, especially for recurrence. In the present case, we report a rare case who could survive long‐term after two surgeries in 4 years for MPM.
Laparoscopic management of traumatic diaphragmatic rupture with herniation of abdominal contents into left hemithorax
Authors: Bairwa Banwari Lal , Anand Ayush 
Published: May 2023

Key Clinical MessageEarly traumatic diaphragmatic rupture diagnosis using radiological investigations and early surgical management is critical to avoid complications.AbstractTraumatic diaphragmatic rupture (TDR) is a rare presentation reported following blunt trauma due to road traffic accidents. Our case showed the importance of early diagnosis of TDR using radiological investigations. Also, early surgical management is critical to avoid complications.
The Uncertain Role of Nominations for the Nobel Prize in Chemistry†
Authors: Seeman Jeffrey I. , Restrepo Guillermo 
Published: May 2023

AbstractThe solicitation of nominations for the Nobel Prizes in Chemistry (NPch) is and has been the first step in the selection process since the very first awards were made in 1901. The number of nominations solicited by and provided to the Nobel Committee for Chemistry supports the belief by the nominators that their nominations are meaningful. In this publication, we examine data culled from the Nobel Prize Nomination Archives for the period 1901–1970 of the variable role of nominations in the selection process for the Nobel Prize in Chemistry. The evidence is overwhelming that nominations, in general, during the 1901–1970 period have not been the deciding, overriding factor in the selection of the recipients of the NPch. Rather, we posit that nominations from the preselected nominator‐pool have been a source of information for the Committee, used to suggest future years’ contenders and possibly served as motivation for the Committee to seek nominations for specific nominees for future years. It is also clear that selections are often influenced by personal prejudices, for example, friendships, rivalries, and nationality.
Novel Method for the Synthesis of Merocyanines: New Photophysical Possibilities for a Known Class of Fluorophores
Authors: Bardi Brunella , Vygranenko Katerina V. , Koszarna Beata , Vakuliuk Olena , Dobrzycki Łukasz , Gryko Daniel T. , Terenziani Francesca , Painelli Anna 
Published: May 2023

AbstractA new, transformative method for the preparation of rhodols and other merocyanines from readily available tetrafluorohydroxybenzaldehyde and aminophenols has been developed. It is now possible to prepare merocyanines bearing three fluorine atoms and additional conjugated rings, and the whole one‐pot process occurs under neutral, mild conditions. Three heretofore unknown merocyanine‐based architectures were prepared using this strategy from aminonaphthols and 4‐hydroxycoumarins. The ability to change the structure of original rhodol chromophore into π‐expanded merocyanines translates to a comprehensive method for the modulation of photophysical properties, such as shifting the absorption and emission bands across almost the entire visible spectrum, reaching a huge Stokes shift i. e. 4800 cm−1, brightness approximately 80.000 M−1 cm−1, two‐photon absorption cross‐section above 150 GM and switching‐on/off solvatofluorochromism. A detailed investigation allowed to rationalize the different spectroscopic behavior of rhodols and new merocyanines, addressing solvatochromism and two‐photon absorption.
Turning the Imidazole Core into Three‐Dimensional Ring Systems: Mild Organocatalytic Entry to Enantiopure 6,7‐Dihydrobenzimidazoles
Authors: Marcantonio Enrico , Guazzetti Debora , Bugatti Kelly , Battistini Lucia , Sartori Andrea , Pelosi Giorgio , Curti Claudio , Zanardi Franca 
Published: May 2023

AbstractOrganocatalytic asymmetric transformation of common aromatic heterocycles via in situ formation of highly reactive dearomatized ortho‐quinodimethane diene species and subsequent [4+2] cycloaddition with suitable dienophiles has become a powerful tool to enter cyclohexane‐fused heterocycles. Most of these reactions were previously applied to benzo‐fused heterocycles or poorly aromatic rings. Herein, we disclose how previously intractable aromatic imidazole rings, equipped with removable methylidene malononitrile activating handle, could be involved as competent cycloaddends with β‐aryl enals in efficient eliminative [4+2] cycloadditions under mild organocatalytic conditions. This method allowed the efficient and direct preparation of scantly represented 6,7‐dihydrobenzo[d]imidazoles with optimal enantio‐ and regioselectivities. Post‐cycloaddition chemical editing provided imidazole‐based ring systems with diverse oxidation state and functional groups.
Xanthene‐Separated 24 π‐Electron Antiaromatic Rosarin Dimer
Authors: Lee Seokwon , Wang Yuying , Dutta Ranjan , Lee Chang‐Hee , Sessler Jonathan L. , Kim Dongho 
Published: May 2023

AbstractAntiaromatic molecules have recently received attention because of their intrinsic properties, such as high reactivity and their narrow HOMO–LUMO gaps. Stacking of antiaromatic molecules has been predicted to induce three‐dimensional aromaticity via frontier orbital interactions. Here, we report a covalently linked π‐π stacked rosarin dimer that has been examined experimentally by steady‐state absorption and transient absorption measurements and theoretically by quantum chemical calculations, including time‐dependent density functional theory, anisotropy of induced current density, and nucleus‐independent chemical shift calculations. Relative to the corresponding monomer, the dimer exhibits diminished antiaromaticity upon lowering the temperature to 77 K, a finding ascribed to intramolecular interactions between the macrocyclic rosarin subunits.
Reduced left ventricular dynamics modeling based on a cylindrical assumption
Authors: Genet Martin , Diaz Jérôme , Chapelle Dominique , Moireau Philippe 
Published: May 2023

AbstractBiomechanical modeling and simulation is expected to play a significant role in the development of the next generation tools in many fields of medicine. However, full‐order finite element models of complex organs such as the heart can be computationally very expensive, thus limiting their practical usability. Therefore, reduced models are much valuable to be used, for example, for pre‐calibration of full‐order models, fast predictions, real‐time applications, and so forth. In this work, focused on the left ventricle, we develop a reduced model by defining reduced geometry & kinematics while keeping general motion and behavior laws, allowing to derive a reduced model where all variables & parameters have a strong physical meaning. More specifically, we propose a reduced ventricular model based on cylindrical geometry & kinematics, which allows to describe the myofiber orientation through the ventricular wall and to represent contraction patterns such as ventricular twist, two important features of ventricular mechanics. Our model is based on the original cylindrical model of Guccione, McCulloch, & Waldman (1991); Guccione, Waldman, & McCulloch (1993), albeit with multiple differences: we propose a fully dynamical formulation, integrated into an open‐loop lumped circulation model, and based on a material behavior that incorporates a fine description of contraction mechanisms; moreover, the issue of the cylinder closure has been completely reformulated; our numerical approach is novel aswell, with consistent spatial (finite element) and time discretizations. Finally, we analyze the sensitivity of the model response to various numerical and physical parameters, and study its physiological response.
Computer data processing method of map manifold based on derivative transfer approach
Authors: Jia Meng , Sun Zheren 
Published: May 2023

SummaryWith the rapid development of Internet technology and the rapid upgrade of hardware devices such as computers and smartphones, the data processed by computers often presents a high dimension. How to reduce data dimension and improve data processing speed is a hot research topic in the computer field. One shortcoming of one‐dimensional manifold calculation methods via sequence points is that the position of new points on the manifold is determined by searching the existing manifold by dichotomy, which is tedious and time‐consuming. This paper improved this method based on derivative transfer. According to the calculation results of one‐dimensional stable and unstable manifolds, they exhibited a special property, that is, for any point on the manifold orbit, its image and preimage must also be on the manifold orbit. Based on this, the derivative transfer method was used to improve the calculation of one‐dimensional manifolds for the map, and a three‐step calculation method of “prediction‐correction‐accuracy verification” was proposed. Then this method was applied to the simulation of high‐dimensional manifolds. The simulation results revealed that the proposed method refined the manifold calculation and greatly enhanced the computation speed.
Growth curves of common factors in psychotherapy: Multilevel growth modelling and outcome analysis
Authors: Meier Deborah , Tschacher Wolfgang , Frommer Angela , Moggi Franz , Pfammatter Mario 
Published: May 2023

AbstractObjectiveA large body of literature discusses change mechanisms underlying psychotherapy with an emphasis on common factors. The present study examined how different comprehensive common factors change over the course of therapy and whether this change was associated with clinical outcome at discharge.MethodThree hundred forty‐eight adults (mean age = 32.1, SD = 10.6; 64% female) attended a standardized 14‐week day‐clinic psychotherapy program. They provided longitudinal data on common factors based on weekly assessments. Additionally, pre‐ and post‐assessment questionnaires on clinical outcome were completed. Using multilevel modelling, we predicted common factors by time (week in therapy). Multiple linear regression models tested the association between changes in common factors and clinical outcome.ResultsThe common factor ‘Therapeutic Alliance’ was best fitted by linear growth models, whereas models for the common factors ‘Coping’, ‘Cognitive Integration’ and ‘Affective Processing’ indicated logarithmic changes over time. ‘Coping’, that is change in patients' ability to cope with their individual problems, was most closely linked with outcome.ConclusionsThe present study provides evidence for the changeability of common factors over the course of therapy as well as their specific contributions to psychotherapeutic progress.
Strawberry breeding for improved flavor
Authors: Porter Mark , Fan Zhen , Lee Seonghee , Whitaker Vance M. 
Published: May 2023

AbstractStrawberry (Fragaria ×ananassa Duchesne ex Rozier) is cultivated and enjoyed globally for its health properties and flavor. Improvements in agronomic performance and fruit quality attributes highlight the successes of strawberry breeding in recent decades. Nevertheless, sweetness and flavor continue to fall below the ideal for the average consumer. While flavor is an important trait of focus, it is one of many critical traits necessary for the success of a strawberry variety. In addition, the chemical complexity of flavor and the genetic complexity of octoploid strawberry have slowed the development of genomics tools for flavor improvement. Recent efforts to understand consumer preference and the chemical drivers of strawberry flavor have revealed the strong impact of sugar content and specific volatile compounds. These large‐scale sensory studies combined with multi‐omics resources have set the stage for new levels of flavor improvement. Marker‐assisted selection for volatile biosynthesis genes has begun to take place in breeding programs, along with genomic selection for increased sugar content. Enhancing levels of existing volatile compounds and targeted introgression of rare compounds using genomics tools will continue to improve flavor intensity and complexity.
A comparative study of oil, protein, and fatty acid content of 12 cultivars of peanut (Arachis hypogaea L.) grown from two regions in Shandong province, China
Authors: Liu Zhaoxin , Li Xiangdong 
Published: May 2023

AbstractPeanut is a primary oil crop that is cultivated on a large scale in Shandong province, China. This study evaluated the oil, protein, and fatty acid compositions of different types of peanut cultivars growing in different ecological regions (Yantai and Heze) in Shandong province from 2019 to 2020. The results showed that the oil content ranged from 38.83% to 56.48%, and the protein content ranged from 21.80% to 31.65% among the studied sites. The oleic acid content and ratio of oleic acid to linoleic acid (O/L) ranged from 39.19% to 52.58% and from 0.92 to 1.77, respectively. Accessions TY107, TY109, and HS‐D‐1 were identified as the most promising oil varieties; HY20 and HY6314 were identified as optimal protein varieties; and HY9311, HY9310, and LH09‐2 were identified as promising varieties for oleic acid production. A significant and positive relationship between seed oil content and accumulated growing degree days (GDD) and insolation duration demonstrated that environments with high temperatures and a long insolation duration promoted oil synthesis. However, a positive relationship was observed only between GDD and protein content. Based on the meteorological conditions of Shandong province, the southwest (such as Heze) is an optimal region for cultivating peanuts with high oil content; the east (Yantai) is most suitable for high‐protein peanut production. The results indicate that the growing conditions should carefully be considered for sustainable and healthy development of the peanut industry as climate variables will likely influence seed composition, thus affecting the suitability for various end uses.
Reciprocal recurrent selection based on genetic complementation: An efficient way to build heterosis in diploids due to directional dominance
Authors: Covarrubias‐Pazaran Giovanny , Werner Christian , Gemenet Dorcus 
Published: May 2023

AbstractDepending on the trait architecture and reproduction system, selection strategies in plant breeding focus on the accumulation of additive, dominance effects, or both. Innovation in the exploitation of dominance‐effect‐based heterosis has been limited since the proposal of general combining ability (GCA)‐based approaches. We propose the use of a new surrogate of genetic complementation between genetic pools to increase accumulation of dominance effects and heterosis. We simulated breeding programs to show how reciprocal recurrent selection (RRS) by genetic complementation would build the dominance‐based heterosis cheaper than GCA‐based approaches and used real phenotypic data from hybrid maize (Zea mays) to demonstrate the underlying concepts. We found RRS by genetic complementation to be an attractive and viable strategy to exploit dominance, build de novo heterotic pools, and enhance the current GCA‐based approaches. If demonstrated in practice, we hypothesized that this approach would lower the cost of hybrid breeding drastically and contribute to food security.
Potential Health Risks of Methylmercury Contamination to Largemouth Bass in the Southeastern United States
Authors: Seymour Ryan D. , Drenner Ray W. , Chumchal Matthew M. 
Published: May 2023

Abstract
Widespread mercury (Hg) contamination of freshwater systems, due primarily to deposition of atmospheric inorganic Hg (IHg), poses a potential threat to recreational fisheries. In aquatic ecosystems, IHg is converted by bacteria to methylmercury (MeHg), a potent toxin that bioaccumulates in consumers and biomagnifies through the food web, reaching elevated concentrations in fish. Methylmercury has concentration-dependent sublethal effects on fish, including reductions in reproductive output. In the present study, we conducted the first analysis of the potential health risks of MeHg contamination to largemouth bass (Micropterus salmoides), a popular game fish, in the southeastern United States. To assess the potential health risk posed by MeHg to largemouth bass, we compared MeHg concentrations in three sizes of adult largemouth bass to benchmarks associated with the onset of adverse health effects in fish. We also determined how the risk posed by MeHg to largemouth bass varied spatially throughout the southeastern United States. Our study suggests that in the southeastern United States MeHg poses a potential risk to largemouth bass health and that MeHg contamination may be detrimental to the fisheries of this economically important species of game fish. Environ Toxicol Chem 2023;42:1755–1762. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Abstract
In the southeastern United States, the potential health risks posed by methylmercury (MeHg) to largemouth bass increases with the average concentration of MeHg in largemouth bass within an ecoregion and largemouth bass size.
Evaluating and Explaining the Variability of Honey Bee Field Studies across Europe Using BEEHAVE
Authors: Agatz Annika , Miles Mark , Roeben Vanessa , Schad Thorsten , van der Stouwe Frederik , Zakharova Liubov , Preuss Thomas G. 
Published: May 2023

Abstract
To assess the effect of plant protection products on pollinator colonies, the higher tier of environmental risk assessment (ERA), for managed honey bee colonies and other pollinators, is in need of a mechanistic effect model. Such models are seen as a promising solution to the shortcomings, which empirical risk assessment can only overcome to a certain degree. A recent assessment of 40 models conducted by the European Food Safety Authority (EFSA) revealed that BEEHAVE is currently the only publicly available mechanistic honey bee model that has the potential to be accepted for ERA purposes. A concern in the use of this model is a lack of model validation against empirical data, spanning field studies conducted in different regions of Europe and covering the variability in colony and environmental conditions. We filled this gap with a BEEHAVE validation study against 66 control colonies of field studies conducted across Germany, Hungary, and the United Kingdom. Our study implements realistic initial colony size and landscape structure to consider foraging options. Overall, the temporal pattern of colony strength is predicted well. Some discrepancies between experimental data and prediction outcomes are explained by assumptions made for model parameterization. Complementary to the recent EFSA study using BEEHAVE, our validation covers a large variability in colony conditions and environmental impacts representing the Northern and Central European Regulatory Zones. Thus we believe that BEEHAVE can be used to serve the development of specific protection goals as well as the development of simulation scenarios for the European Regulatory Zone. Subsequently, the model can be applied as a standard tool for higher tier ERA of managed honey bees using the mechanistic ecotoxicological module for BEEHAVE, BEEHAVEecotox. Environ Toxicol Chem 2023;42:1839–1850. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Abstract
BEEHAVE evaluation on honey bee field studies conducted in Germany, Hungary, and the United Kingdom. OSR = oil seed rape.
Addressing Coldwater Temperature Impairment in a Changing Climate
Authors: Kusnierz Paul C , Leiman Jonathan , Jager Henriette I 
Published: May 2023

Abstract
Climate change is concerning for fisheries professionals because increased water temperatures threaten coldwater habitats, which are vital to recreational and commercial fisheries and keystone species. The Clean Water Act provides a legal framework to identify and address water quality impairments including those associated with temperature. Although this framework provides a basic strategy to identify impairments, develop total maximum daily loads, and reduce pollution, it does not explicitly consider the challenges of a changing climate in addressing water quality impairments. Clean Water Act administrators and fisheries professionals can facilitate temperature restoration planning and implementation using the Clean Water Act framework to link stakeholders to the management of coldwater resources. Stakeholder engagement and collaboration, robust local monitoring, and incorporating climate resilience into restoration planning and implementation will promote comprehensive management of temperature impairments and the effects of climate change on fisheries.
The Kimberlina synthetic multiphysics dataset for CO2 monitoring investigations
Authors: Alumbaugh David , Gasperikova Erika , Crandall Dustin , Commer Michael , Feng Shihang , Harbert William , Li Yaoguo , Lin Youzuo , Samarasinghe Savini 
Published: May 2023

AbstractWe present a synthetic multi‐scale, multi‐physics dataset constructed from the Kimberlina 1.2 CO2 reservoir model based on a potential CO2 storage site in the Southern San Joaquin Basin of California. Among 300 models, one selected reservoir‐simulation scenario produces hydrologic‐state models at the onset and after 20 years of CO2 injection. Subsequently, these models were transformed into geophysical properties, including P‐ and S‐wave seismic velocities, saturated density where the saturating fluid can be a combination of brine and supercritical CO2, and electrical resistivity using established empirical petrophysical relationships. From these 3D distributions of geophysical properties, we have generated synthetic time‐lapse seismic, gravity and electromagnetic responses with acquisition geometries that mimic realistic monitoring surveys and are achievable in actual field situations. We have also created a series of synthetic well logs of CO2 saturation, acoustic velocity, density and induction resistivity in the injection well and three monitoring wells. These were constructed by combining the low‐frequency trend of the geophysical models with the high‐frequency variations of actual well logs collected at the potential storage site. In addition, to better calibrate our datasets, measurements of permeability and pore connectivity have been made on cores of Vedder Sandstone, which forms the primary reservoir unit. These measurements provide the range of scales in the otherwise synthetic dataset to be as close to a real‐world situation as possible. This dataset consisting of the reservoir models, geophysical models, simulated time‐lapse geophysical responses and well logs forms a multi‐scale, multi‐physics testbed for designing and testing geophysical CO2 monitoring systems as well as for imaging and characterization algorithms. The suite of numerical models and data have been made publicly available for downloading on the National Energy Technology Laboratory's (NETL) Energy Data Exchange (EDX) website.