bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thymol@Natural Zeolite Nanohybrids for Chitosan/Polyvinyl-Alcohol-Based Hydrogels Applied as Active Pads
Authors: Salmas Constantinos E. , Kollia Eleni , Avdylaj Learda , Kopsacheili Anna , Zaharioudakis Konstantinos , Georgopoulos Stavros , Leontiou Areti , Katerinopoulou Katerina , Kehayias George , Karakassides Anastasios , Proestos Charalampos , Giannakas Aris E. 
Published: July 2023

Currently, food saving, a circular economy, and zero environmental fingerprints are of major interest. Scientific efforts for enhanced food preservation using “green” methods have been intensified. Even though chemicals could achieve such targets effectively, the global trend against the “greenhouse effect” suggests the use of environmentally friendly biobased materials for this purpose. In this study, the promising biopolymer chitosan is incorporated with the promising biodegradable polymer polyvinyl alcohol to produce an improved biopolymeric matrix. This biodegradable biopolymer was further mixed homogeneously with 15% thymol/nano-zeolite nanohybrid material. The properties of the final developed film were improved compared to the relevant values of chitosan/polyvinyl alcohol film. The mechanical properties were enhanced significantly, i.e., there was a 34% increase in Young’s modulus and a 4.5% increase in the ultimate tensile strength, while the antioxidant activity increased by 53.4%. The antibacterial activity increased by 134% for Escherichia coli, 87.5% for Staphylococcus aureus, 32% for Listeria monocytogenes, and 9% for Salmonella enterica. The water vapor diffusion coefficient and the oxygen permeability coefficient decreased to −51% and −74%, respectively, and thus, the water vapor and oxygen barrier increased significantly. The active pads were used in strawberries, and the antimicrobial activity evaluation against the mold of fungi was carried out. The visual evaluation shows that the active pads could extend the shelf life duration of strawberries.
The Role of Clinical Questioning Using the Scale of Hemorrhagic Manifestations in the Diagnosis of von Willebrand’s Disease
Authors: Кабаева Е.Н. 
Published: July 2023

Болезнь Виллебранда – наиболее распространенная наследственная геморрагическая гемостазиопатия. Частота заболевания в популяции составляет 1–2%. Формы болезни Виллебранда с выраженными клиническими проявлениями встречаются с частотой 0,1%. Причиной болезни Виллебранда является количественный или качественный дефект фактора Виллебранда, что определяет разнообразие клинических и лабораторных проявлений заболевания. Следует отметить, что основным контингентом пациентов с болезнью Виллебранда, наблюдающихся у гематолога, являются женщины. Это обусловлено тем, что если среди всех женщин в менструальном периоде около 12% страдают меноррагиями, то среди женщин с болезнью Виллебранда эта доля может возрасти до 95%. Чувствительность меноррагии как предиктора болезни Виллебранда составляет 32–100% со специфичностью 5–20%. Диагноз болезни Виллебранда базируется на оценке клинических проявлений, семейного анамнеза, данных лабораторного обследования. Другие характерные проявления повышенной кровоточивости у пациентов с болезнью Виллебранда – это кровотечения из слизистых полости носа и рта, кровоточивость в местах незначительных повреждений кожных покровов, после оперативных вмешательств, экстракций зубов, возможно развитие гемартрозов и межмышечных гематом. В связи с разнообразием клинических и лабораторных проявлений заболевания с целью скрининга специфических жалоб и анамнеза различными центрами разработано несколько вариантов балльных шкал, которые помогают врачу выявить потенциальных пациентов с болезнью Виллебранда.
Willebrand disease (VWD) is the most common hereditary hemorrhagic hemostasiopathy. The frequency of the disease in the population is 1–2%. Forms of VWD with severe clinical manifestations occur with a frequency of 0.1%. The cause of VWD is a quantitative or qualitative von Willebrand factor (VWF), which determines the variety of clinical and laboratory manifestations of the disease. It should be noted that the main contingent of patients with VWD seen by a hematologist are women This is because while menorrhagia during the menstrual period occurs in about 12% of all women, this proportion can rise to 95% among women with VWD. The sensitivity of menorrhagia as a predictor of VWD is 32–100%, with a specificity of 5–20%. The diagnosis of VWD is based on an assessment of clinical manifestations, family history, and laboratory examination data. Other characteristic manifestations of increased bleeding in patients with VWD are bleeding from the mucous membrane of the nasal cavity and mouth, bleeding in places of minor damage to the skin, after surgical interventions, extractions of teeth, hemarthrosis and intermuscular hematomas may develop. Due to the variety of clinical and laboratory manifestations of the disease, in order to screen for specific complaints and anamnesis, various centers have developed several options for scoring scales that help the doctor identify potential patients with VWD.
Medical, Demographic and Social Aspects of Arterial Hypertension in Pregnant Women
Authors: Тагиева Ф.А. 
Published: July 2023

С целью изучения медико-демографических и социальных аспектов артериальной гипертензии у беременных был проведен анализ историй родов 218 женщин. Средний возраст у беременных с артериальной гипертензией был равен 27,8±0,40 года. Частота артериальной гипертензии у беременных составила 39,6%. Распределение пациенток по социальному статусу показало, что среди беременных с артериальной гипертензией чаще встречались домохозяйки. Изучение сопутствующей соматической патологии у обследованных беременных показало, что у них диагностировались заболевания сердечно-сосудистой системы, желудочно-кишечного тракта, эндокринные заболевания, болезни мочевыделительной системы, острые респираторные вирусные инфекции и грипп. У беременных с артериальной гипертензией достоверно чаще выявляются такие факторы риска, как ожирение и отягощенная наследственность по артериальной гипертензии. У беременных с артериальной гипертензией наблюдалась различная соматическая патология. В акушерско-гинекологическом анамнезе отмечался нерегулярный менструальный цикл, поли- и олигоменорея.
In order to study the medical, demographic and social aspects of arterial hypertension in pregnant women, an analysis of the birth histories of 218 women was carried out. The mean age in pregnant women with arterial hypertension was 27.8±0.40 years. The frequency of arterial hypertension in pregnant women was 39.6%. The distribution of patients by social status showed that among pregnant women with arterial hypertension, housewives were more common. The study of concomitant somatic pathology in the examined pregnant women showed that they were diagnosed with diseases of the cardiovascular system, gastrointestinal tract, endocrine diseases, diseases of the urinary system, acute respiratory viral infections and influenza. In pregnant women with arterial hypertension, such risk factors as obesity and aggravated heredity for arterial hypertension are significantly more often detected. In pregnant women with arterial hypertension, various somatic pathologies were observed. In the obstetric and gynecological history, an irregular menstrual cycle, poly- and oligomenorrhea were noted.
The Impact of Acute Respiratory Coronavirus Infection on the Outcome of Childbirth, the Condition of the Mother, Fetus and Newborn at 38–40 Weeks of Gestation
Authors: Гулиева Х.Г. 
Published: July 2023

Цель исследования. Изучить исход беременности и родов для матери, плода и новорожденного у женщин с острой коронавирусной инфекцией. Материалы и методы. Обследовано 55 пациентов с острой коронавирусной инфекцией в 38–40 недель беременности. Средний возраст обследованных беременных и рожениц составил 28,13±0,58 года. Были проведены клинические, функциональные, лабораторные, биохимические, радиологические методы исследования. Для подтверждения коронавирусной инфекции были взяты мазки из горла и носа и определены методом полимеразной цепной реакции (ПЦР). Результаты. Установлено, что у беременных, инфицированных острой коронавирусной инфекцией, в 38–40 недель частота спонтанных родов через естественные родовые пути составила 27,3%, частота абдоминального родоразрешения была в пределах 72,7%. Внутриутробное инфицирование плода от беременных с острой коронавирусной инфекцией в 38–40 недель не наблюдалось. Новорожденные находились на грудном вскармливании. Ограниченный контакт матери и ребенка позволил избежать инфицирования новорожденных. Заключение. В результате проведенного исследования было установлено, что 61% беременных и рожениц были госпитализированы в состоянии средней тяжести, 36,4% – в удовлетворительном состоянии.
Purpose of the study. To study the outcome of pregnancy and childbirth for mother, fetus and newborn in women with acute coronavirus infection at gestational age 38–40 weeks. Material and methods. There were examined 55 patients with acute coronavirus infection at 38–40 weeks of pregnancy. The average age of the pregnant women and women in labor was 28.13±0.58 years. Clinical, functional, laboratory, biochemical, radiological research methods were conducted. To confirm coronavirus infection, there were performed throat and nose swabs with further detection of the virus by polymerase chain reaction (PCR). Results. It was found that in pregnant women infected with acute coronavirus infection at 38–40 weeks, the frequency of spontaneous vaginal birth was 27.3%, the frequency of abdominal delivery was within 72.7%. Intrauterine infection of the fetus from mother with acute coronavirus infection at 38–40 weeks was not observed. The newborns were breastfed, and limited contact between mother and child made it possible to avoid contamination of newborns. Conclusion. As a result of the study, it was found that 61% of pregnant women and women in labor were hospitalized in a moderate condition, 36.4% in a satisfactory condition.
Urinary Incontinence in Women: a Modern Approach to the Problem and Treatment Recommendations
Authors: Бурьяк Д.В. 
Published: July 2023

Недержание мочи является распространенным заболеванием, возникающим у женщин всех возрастных групп и существенно влияющим на качество их жизни. В данной статье представлены научно обоснованные данные по этиологии, причинам возникновения недержания мочи у женщин, факторам риска, классификации, подходам к диагностике, лечению и последующему наблюдению. В разделе лечения приведена информация о немедикаментозных, фармакологических и хирургических методах лечения, включая перспективные разработки. Применение современных подходов к тактике ведения пациенток с недержанием мочи позволяет улучшить результаты терапии, повысить качество жизни пациенток и предотвратить появление нежелательных осложнений.
Urinary incontinence is a common condition affecting women of all age groups and significantly impairing their quality of life. This article presents evidence-based data on the etiology, causes of urinary incontinence in women, risk factors, classification, approach to diagnosis, treatment and follow-up. The treatment section provides information on non- pharmaceutical, pharmacological, and surgical treatments, including the emerging ones. The use of modern approaches to the management of patients with urinary incontinence can improve the results of therapy, the quality of life of patients and prevent the occurrence of unwanted complications.
Study of the optimal mode of sludge agitation in the receiving tank of a wastewater pumping station
Authors: Григорьева А.Н. 
Published: July 2023

Взмучивание осадка в приемном резервуаре канализационной насосной станции является достаточно серьезной проблемой из-за большого риска выхода из строя насосного оборудования, а также слеживания и загнивания осадка в самом резервуаре. Как правило, методы борьбы с оседанием осадка направлены на освобождение только области вблизи всасывающих патрубков насосов. В остальной же части резервуара слежавшийся осадок периодически вымывают вручную в периоды технического обслуживания или минимального заполнения. Приводится сравнение двух методов взмучивания осадка в приемном резервуаре канализационной насосной станции. В первом случае осадок взмучивается гидравлическим способом – с помощью трубопроводов, расположенных по периметру емкости. Во втором используются конические мешалки усовершенствованной геометрии, то есть взмучивание осадка осуществляется механическим способом. Сравнение эффективности перемешивания производилось при помощи CFD-моделирования. Согласно результатам моделирования гидродинамики перемешивания, при работе конических мешалок практически не образуются застойные зоны в придонной области перемешивания.
Sludge agitation in the receiving tank of a wastewater pumping station is a rather serious problem due to the high risks of the pumping equipment failure, sludge caking and decay inside the tank. As a rule, sludge settling control methods provide for emptying only the area close to the suction nozzles of the pumps. In the rest of the tank, the caked sludge is periodically washed out by hand during maintenance or minimum filling. A comparison is made between two methods of sludge agitation in the receiving tank of a wastewater pumping station. In the first case, sludge is agitated hydraulically, i. e., using pipelines located along the perimeter of the tank. In the second, conical mixers of improved geometry are used, that is, sludge is agitated mechanically. A comparison of mixing efficiency was made using CFD-modeling. According to the results of modeling the hydrodynamics of mixing, during the operation of conical mixers, no stagnant zones is actually formed in the near-bottom mixing area.
Penetapan kadar flavonoid total ekstrak etanol buah asam kandis (Garcinia xanthochymus) dengan metode spektrofotometri Uv-Vis dan LCMS
Authors: Winata Hanafis Sastra , Faisal Hendri , Andry Muhammad , Aulia Nurul , Nasution Muhammad Amin , Tambunan Ika Julianti 
Published: July 2023

Pendahuluan: Buah asam kandis (Garcinia xanthocymus Hook.f ex T.Anderson) merupakan tumbuhan jenis famili Clusiase dan termasud pada jumlah spesies yang cukup banyak. Buah asam kandis mempunyai variasi dalam hal aktivitas biologis dan farmakologis diantaranya sitotoksik, antiinflamasi, antimikroba, antifungi dan antioksidan. Tujuan: Untuk mengetahui kandungan dan kadar flavonoid total buah asam kandis dengan menggunakan baku pembanding kuersetin.
Metode: Penelitian ini dilakukan dengan metode KLT (Kromatografi Lapis Tipis) menggunakan analisis kualitatif dengan parameter Rf, kemudian menggunakan metode spektrofotometri dalam analisis kuantitatif dengan parameter kadar flavonoid total (Nilai mg QE/g sampel) dan Metode LCMS (Liquid Crhomatograph Mass Spectomety) dengan parameter waktu retensi (Rt). Hasil: Menunjukkan bahwa buah asam kandis memiliki nilai Rf 0,86 yang menyatakan buah asam kandis positif flavonoid dengan baku pembanding kuersetin, kadar flavonoid total sebesar 34,8364 mg QE/g sampel dengan standar devisi 0,4355 dan persentase 0,6967 % dan memiliki 5 jenis senyawa flavonoid yaitu methyl dihydro quersetin, 1,5-Dihydroxy-3- methoxy xanthone, Afzelechin, Myricetin-3-O-ß-D-galactopiranoside, dan Myricetin 7- glucoside. methyl dihydro quersetin merupakan flavonoid dengan komposisi terbesar yakni sebesar 49,57 % dengan waktu retensi menit 0,485. Kesimpulan: Total flavonoid yang teridentifikasi memiliki jenis dan kadar yang berbeda-beda.
Uji Efektivitas Etanol Daun Pandan (Panandus amarylifolius Roxb) Sebagai Penyembuhan Luka Sayat pada Tikus Putih (Rattus norvegicus)
Authors: Londoran Priska C. , Kanter Jabes W. , Sambou Christel N. , Hariyadi Hariyadi 
Published: July 2023

Luka sayat merupakan area kulit yang tersayat dikarenakan terkena benda tajam . Masyarakat Indonesia sangat banyak menggunakan tanaman obat dalam pengobatan tradisional ataupun modern. Salah satu tanaman yang dapat menjadi bahan obat yaitu daun pandan wangi yang dapat mempercepat proses penyembuhan luka. Sehingga penelitian ini dilakukan untuk mengetahui tingkat efektivitas yang terdapat pada sari daun pandan. Penelitian ini menggunakan tikus putih sebanyak 15 ekor yang kemudian di sayat dibagian punggungnya dengan menggunakan surgical blades sepanjang 1 cm dengan kedalaman ± 2 mm. Penelitian ini menggunakan eksperimental laboratorium dengan menggunakan rancangan acak lengkap yang terdiri dari 5 kelompok perlakuan, diantaranya 1 negative control, positive control (povidone iodine 10 persen) dan 3 konsentrasi bertingkat yaitu sari daun pandan konsentrasi 5, 10 hingga 15 persen dengan masing-masing 2 kali pengulangan. Hasil pengukuran panjang luka pada tikus menunjukkan bahwa sari daun pandan wangi konsentrasi 10 persen dan 15 persen memiliki efektivitas yang sama baiknya.
KUAT TEKAN CAMPURAN ROLLER COMPACTED CONCRETE (RCC) DENGAN MENGGUNAKAN SILIKA FUME DAN SUPER PLASTICIZER
Authors: Galih Rio Prayogi  , Indri Rahmandhani Fitriana  
Published: July 2023

Roller Compacted Concrete (RCC) menjadikan alternatif perkerasan kaku di desain dengan beton mutu tinggi agar mendapatkan hasil yang maksimal untuk perkerasan di indonesia dikarena pekerjaan lebih cepat dan material lebih ekonomis dan kecepatan konstruksi lebih tinggi. Penelitian ini menggunakan nilai faktor air semen (FAS) yang rendah yakni 0,25 dan bahan mineral yakni silica fume serta bahan kimia super plasticizer atau water reducer. Proporsi yang digunakan pada penelitian yakni penggunaan 10% silika fume dengan variasi penggunaan super plasticizer 2,4% dan 0,6%. Proses pemadatan campuran RCC menggunakan alat penumbuk standard proctor dengan berat alat penumbuk 2,5 kg ditumbuk sebanyak 25 tumbukan/lapis dalam 3 lapis. Benda uji menggunakan silinder dengan ukuran 100x200 mm, pengujian kuat tekan beton umur 1 dan 28 hari. Hasil penelitian pengujian kuat tekan umur 1 hari dengan Variasi 2,4% yakni 25,25 Mpa sedangkan kuat tekan beton umur 28 hari dengan 38,24 MPa. Nilai kuat tekan beton pada umur 28 hari telah masuk dalam spesifikasi range kuat tekan beton Roller Compacted Concrete (RCC) pada umumnya berkisar antara 4000 sampai 6000 Psi (28 sampai 41 MPa).
LIMITATIONS OF AUTHORITY OF THE CENTRAL AND REGIONAL GOVERNMENTS IN THE RECRUITMENT OF NON-ASN EMPLOYEES
Authors: Purnomo Riyadi Sri , Saragi Frenky Kristian 
Published: July 2023

Pengadaan pegawai non-ASN masih menjadi permasalahan yang belum terselesaikan dengan optimal sampai saat ini. Berdasarkan pendataan yang dilakukan Kementerian PAN dan RB bersama BKN pada Bulan Mei-Oktober 2022, jumlah pegawai non-ASN melonjak drastis menjadi 2.360.723 dari sebelumnya yang hanya berjumlah 363.934. Berbagai kebijakan sudah dilakukan oleh pemerintah untuk mengerem bertambahnya jumlah pegawai non-ASN ini. Namun karena belum jelasnya batasan kewenangan antara pemerintah pusat dan daerah menjadikan rekrutmen pegawai non-ASN dengan berbagai pengistilahan masih dilakukan oleh pemerintah daerah dengan argumentasi pemenuhan kebutuhan pegawai untuk memberikan pelayanan yang optimal bagi publik. Rekomendasi kebijakan yang dapat diberikan untuk memperbaiki penataan dan manajemen pegawai pemerintah non-ASN ini yaitu: (1) Pemerintah melalui Kementerian PAN dan RB tetap berpegang teguh pada komitmen awal bahwa Kementerian/ Lembaga/ Pemerintah Daerah tidak diperbolehkan lagi mengangkat pegawai diluar PNS dan PPPK, agar sesuai amanat UU ASN dan PP Manajemen PPPK yaitu hanya ada 2 jenis kepegawaian yang ada di instansi pemerintah: PNS dan PPPK, (2) Merumuskan grand design penyelesaian permasalahan pegawai non-ASN, (3) Untuk memperjelas batasan kewenangan yang dimiliki oleh Pemerintah Pusat dalam hal ini Kementerian PAN dan RB dan instansi di daerah, perlu diatur dalam sebuah kebijakan tentang kewenangan pemerintah daerah yang masih di perbolehkan dalam melakukan pengadaan pegawai non-ASN yang didasarkan pada penyelenggaraan pelayanan publik yang krusial yang didasarkan pada perjanjian kerja, kinerja pegawai, dan kebutuhan pegawai di Pemerintah Daerah selama periode tertentu.
Kata Kunci: Batasan Kewenangan, Pegawai non-ASN, Pemerintah Pusat, Pemerintah Daerah
DEVELOPMENT Pengembangan Bahan Ajar Materi Ekosistem Rawa Gambut Berbasis eLEMA
Authors: Araina Elga , Savitri Shanty , Mashabhi Sugeng , Pratama Fernando 
Published: July 2023

Media digital interaktif berbasis android aplikasi eLEMA (Electronic Learning Material) merupakan implementasi pendidikan jarak jauh melalui online jaringan internet, solusi kegiatan belajar mengajar (KBM) yang efektif. Penunjang Materi Ekosistem terkhususnya Ekosistem Hutan Rawa Gambut yang masih minim didapatkan. Penelitian pengembangan menggunakan jenis penelitian Research and Development(R&D) model Hannafin and Peck terdiri dari 3 phase Analysis, Design, Develop/Implementation. Hasil penelitian bahan ajar digital berbasis eLEMA menghasilkan produk berupa RPS, bahan ajar, suplemen materi dan LKM telah memenuhi komponen sebagai perangkat pembelajaran dan dapat digunakan dalam proses pembelajaran. Berdasarkan hasil validasi dari ahli materi, ahli media dan respon mahasiswa dengan kriteria baik dan layak digunakan. Aplikasi eLEMA memudahkan mahasiswa dapat mengakses materi secara online maupun offline.
Analisis Indek Kepuasan Masyarakat / IKM Di Rumah Sakit Umum Hasanuddin Damrah Manna Kabupaten Bengkulu Selatan
Authors: Susana Triza , Afriani Sulisti , Nurzam Nurzam 
Published: July 2023

At epoch of pandemi which now again world, health represent an elementary requirement to society. Requirement that's making society feel important to keep in good health and obtain;get service of health. These days society progressively aware of quality or quality service of health capable to give satisfaction [at] society itself. In a condition this time Hospital party/ side have have to know how quality of service of them can be accepted by its consumer, patient goodness take care of to lodge and also outpatient. Quality of service very closely related with cutomer/ client.
Target doing/conducting of this research is to know analysis of indek satisfaction of society / IKM at home Common/ Public Pain of Hasanuddin Damrah Paradise Fruit Sub-Province of Bengkulu South. Type Research in this research is descriptive by wearing method research of Kusioner. While technique analyse data the used is by using measurement of value Make An Index To Satisfaction of Society / IKM pursuant to Regulation Of Minister Utilization Of State Aparatus And Reform Bureaucracy Republic Of Indonesia Number 14 Year 2017 About Guidance Of Compilation Of Survey Satisfaction Of Society Unit Organizer of Service of counted/calculated Public by using average value deliberated by the each service element.
Result of this research can know that From 9 element service of society exist in common/ public hospital of Hasanuddin Damrah Paradise fruit, average value the got is equal to 3,09. Average value deliberated by at entire/all service element is 3,06. So that in earning conversion assess satisfaction of society exist in Common/ Public Hospital of Hasanuddin Damrah Paradise fruit is 76, 48 with quality of service " B" or predikat Whether.