bluuebunny/crossref_metadata_2025_split huggingface dataset:
The content and effectiveness of physical activity for cancer‐related fatigue among colorectal cancer survivors: Systematic review and meta‐analysis
Authors: Geng Liangrong , Li Xiaoyu , Guo Liqun , Zhang Rui , Yue Shujin 
Published: April 2023

AbstractAimsTo review the content and efficacy of physical activity (PA) for cancer‐related fatigue (CRF) among colorectal cancer survivors.DesignSystematic review.MethodsA comprehensive search for randomized controlled trials from inception to April 1, 2022, of the following database was performed: EMBASE, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data and China Biology Medicine (CBM). RevMan5.4 software was used for performing meta‐analysis.ResultsA total of eight qualified randomized controlled trials that included 542 survivors were included. PA interventions significantly reduced the CRF (SMD = −0.46; 95% CI: [−0.76, −0.15], Z = 2.67, p = 0.003); Subgroup analysis showed that fatigue was significantly improved when the length of interventions was at least 6 months and the weekly duration of PA was less than 150 min/week (SMD = −0.54; 95% CI: [−0.81, −0.27], Z = 3.87 and p = 0.0001; SMD = −0.67; 95% CI: [−1.15, −0.19], Z = 2.74 and p = 0.006); PA intervention with the length of <6 months and the volume of ≥150 min/week did not reduce fatigue (p > 0.05).
Additive manufacturing of silicone composite structures with continuous carbon fiber reinforcement
Authors: Liu Wenbo , Peeke Lachlan M. , Periyasamy Mookkan , Campbell Ronald R. , Hickner Michael A. 
Published: April 2023

AbstractAs a relatively new material deployed in additive manufacturing (AM), silicone and its composites have the potential to realize tunable functionality and heterogeneous, architected properties for a number of applications requiring low modulus, elastic materials. Continuous fiber reinforced composites have been developed for AM to achieve various complex structures that are lightweight with high mechanical properties. AM of silicone‐based composites with direct ink writing (DIW) technology has potential application in medical devices, gasket components, flexible soft electronics, and food packaging. However, DIW printed materials have mechanical anisotropy since the extrusion‐based printing process creates small changes in geometry during the material deposition process. In addition, silicone elastomers are relatively low modulus in tension and can be reinforced with woven cloth or fibers. In this work, a continuous fiber AM machine is developed to manufacture silicone composite structures with continuous fiber reinforcing the printed silicone. Tensile tests show that the anisotropic property of the perpendicular printed specimens, relative to the tension direction, has been significantly improved by continuous carbon fiber reinforcements. This continuous fiber silicone reinforcement printing technique can be applied to tune fiber volume ratios and orientations for different silicone composite structures to meet the desired strength and stiffness.
Frustrated crystallization behavior under hierarchical confinement in electrospun fibers of poly(styrene)/poly(ethylene oxide)/poly(l‐lactide) ternary mixtures
Authors: Pal Sanchayan , Srivastava Rajiv K. , Nandan Bhanu 
Published: April 2023

AbstractThe crystallization behavior of binary crystalline mixtures composed of poly(ethylene oxide) (PEO) and poly(l‐lactide) (PLLA) was investigated in the electrospun nanofibers fabricated by the ternary blends of polystyrene (PS), PEO, and PLLA. The weight fraction of PEO/PLLA mixture was kept at ≤0.2 such that PS formed the matrix phase. The preferred mixing of PEO and PLLA resulted in the formation of mixed PEO/PLLA dispersed domains in the PS matrix. The small diameter of the electrospun nanofibers restricted the size of dispersed domain. During cooling from melt, PLLA crystallized first resulting in crystallization induced phase separation and entrapment of PEO within the intracrystalline regions of PLLA crystals. Hence, whereas the PLLA crystallized within the soft PS matrix, the crystallization of PEO occurred within the hierarchical confinement imposed by the PLLA crystals as well as the glassy PS matrix. Interestingly, it was found that the confinement favored the formation of α crystals phase in PLLA even at very low crystallization temperatures. Furthermore, due to plausible entrapment of PEO segments within the PLLA crystals, significant depression in PLLA melting temperature was observed. Moreover, the PEO melting temperature also depressed by more than 30°C due to the frustrated crystallization within the hierarchical confinement.
Water vapour products from ERA5, MERSI‐II/FY‐3D, OLCI/Sentinel‐3A, OLCI/Sentinel‐3B, MODIS/Aqua and MODIS/Terra in Australia: A comparison against in situGPS water vapour data
Authors: Xu Jiafei , Liu Zhizhao 
Published: April 2023

AbstractAustralia is a region of high sensitivity to the El Niño–Southern Oscillation events in association with atmospheric water vapour, which is an essential atmospheric parameter in hydrological cycle, energy transport and climate monitoring. In this article, we thoroughly validated the quality of multisource precipitable water vapour (PWV) products sourced from ERA5 reanalysis, advanced Medium Resolution Spectral Imager (MERSI‐II) sensor on the FY‐3D satellite, Ocean and Land Colour Instrument (OLCI) sensor on the Sentinel‐3A and Sentinel‐3B satellites, and Moderate Resolution Imaging Spectroradiometer (MODIS) sensor on the Aqua and Terra satellites. The PWV estimates measured by 453 in situ Global Positioning System (GPS) sites from 1 June 2019 to 31 May 2020 over Australia were employed as the common reference. The validation results show that all the reanalysis‐based and satellite‐based PWV products had a good agreement with reference GPS‐based PWV data. ERA5 reanalysis had the highest PWV accuracy with a root‐mean‐square error (RMSE) of 2.016 mm and a relative RMSE (RRMSE) of 12.038%, while the MODIS/Terra instrument had the lowest PWV accuracy (RMSE = 4.903 mm and RRMSE = 34.187%). In contrast to the MERSI‐II/FY‐3D instrument that underestimated PWV, the PWV data from ERA5, OLCI/Sentinel‐3A, OLCI/Sentinel‐3B, MODIS/Aqua and MODIS/Terra overestimated the water vapour values. The quality of reanalysis‐based and satellite‐based PWV measurements showed significant dependencies on several variables – location, PWV, solar zenith angle, season, elevation, land surface cover and latitude. It is expected that this research can help enhance the understanding of the quality of reanalysis and satellite water vapour products in Australia, that is, ERA5, OLCI/Sentinel‐3A, OLCI/Sentinel‐3B, MODIS/Aqua and MODIS/Terra. This work could provide an insight into improving the accuracy of reanalysis‐based and satellite‐based PWV data products after exploring the dependency factors that affect PWV performance as presented in our work.
Investigation of turbulent flows using spillway models aiming to aid downstream migration of fish
Authors: Shirinzad A. , Kumahor S. , Tachie M. F. , Ghamry H. , Katopodis C. 
Published: April 2023

AbstractDams and other flow control structures constitute obstacles to upstream and downstream aquatic habitats, reducing life‐cycle success and even eliminating diadromous and potamodromous fish species from river basins. Providing effective passage past hydroelectric dams is critical for restoring habitat connectivity and sustaining populations of fish species. Surface water release over spillways is effective in diverting fish from turbines and establishing a safe bypass for downstream migrants. Developing an effective passage system over spillways requires both biological knowledge of fish behavior and abilities, as well as hydraulic knowledge of spillway flows to provide hydrodynamic conditions that fish may exploit. The present study experimentally investigates several depths, velocity, and turbulence fields intended to promote the downstream migration of fish over spillways. Instantaneous velocity fields were measured in an open recirculating rectangular water channel. A 90° standard spillway model, as well as a spillway model with a modified upstream face slope of 45°, were tested for two water depths. The results show the presence of a distinct recirculation bubble at the heel of the 90° standard spillway with the shallower water depth. It was concluded that the upstream recirculation bubble may be suppressed by either increasing the water depth or decreasing the upstream face slope. Decreasing the upstream face slope also resulted in a more uniform distribution of acceleration and lower turbulence along the upstream face of the spillway. The modified spillways provide more suitable hydrodynamic conditions for downstream migrants.
Fine‐scale landscape phenology revealed through time‐lapse imagery: implications for conservation and management of an endangered migratory herbivore
Authors: John Christian , Kerby Jeffrey T. , Stephenson Thomas R. , Post Eric 
Published: April 2023

AbstractClimate change modifies plant phenology through shifts in seasonal temperature and precipitation. Because the timing of plant growth can limit herbivore population dynamics, climatic alteration of historical patterns of vegetation seasonality may alter population trajectories in such taxa. Thus, sound management decisions may depend on understanding how plant growth varies across a landscape within and among distinct management units or protected areas. Here, we examine spatial variation in the timing of spring plant growth, measured using a network of automated time‐lapse cameras distributed across the range of endangered Sierra Nevada bighorn sheep (Ovis canadensis sierrae) in California, USA. We tracked greenness of individual plants across 2 years to compare spatial patterns of forage phenology in snowy and drought years. Green‐up timing was derived for individual plants across the camera network and compared with local estimates of green‐up timing from satellite data. Satellite‐derived estimates of green‐up timing showed strong correspondence with camera‐derived estimates in areas with dense vegetation cover and weak correspondence in areas with sparse vegetation cover. Daily time‐lapse imagery revealed consistent variation in green‐up timing across elevation, both among latitudinal zones and among individual plant species. Green‐up timing was earlier in 2020 than in 2019, reflecting differences in the end of the snowy season. Because bighorn forage seasonally on alpine species with a brief growing period, spring migration of bighorn may be linked to variation in snowmelt and plant growth across elevational gradients.
Synthesis of Ni/Co/Ni−G Composite Coatings and Analysis of Their Corrosion Resistance Properties to Q235 Carbon Steel
Authors: Xie Xiang , Qiao Gaoqun , Wang Xiaohu , Wang Xinzhen 
Published: April 2023

AbstractIn this work, nickel‐modified graphene nanosheets (Ni−G) were prepared by hydrothermal method for the first time. The microscopic morphological analysis showed that the nickel nanoparticles were successfully reductively deposited on the surface of Ni−G with uniform distribution. Ni−G can be uniformly and stably dispersed in the electrodeposition solution. Then Ni/Co/Ni−G composite coating was prepared by pulsed current co‐deposition method to provide corrosion resistance protection for Q235 carbon steel. The microstructure and morphology analysis of the composite coating shows that Ni−G were homogeneously incorporated in the coating and the composite coatings were uniform, dense and crack‐free. The hardness test results showed that the doping of Ni−G improved the hardness of the composite coating. The influence of the added amount of Ni−G in the electrodeposition solution on the anti‐corrosion performance of the composite coating was investigated. The electrochemical results illustrated that the composite coating prepared by adding 20 mL Ni−G dispersion achieved 98.04 % protection efficiency (
EIS) against carbon steel substrate in 3.5 wt.% NaCl solution, the Ni/Co/Ni−G20 composite coating has the best corrosion resistance.
Straightforward Synthesis of Trifluoromethylated Arenes via Copper‐Mediated Trifluoromethylation of Diaryliodonium Salts with Fluoroform
Authors: Zhang Jida , Feng Xiaomei , Guo Taiyang , Han Xuliang , Liu Haodong , Li Xiangye , Wang Xin , Li Hansheng , Li Xinjin 
Published: April 2023

AbstractA mild and efficient copper‐mediated trifluoromethylation of diaryliodonium salts with readily available fluoroform has been developed. The reaction exhibits excellent functional group tolerance, affording trifluoromethylated arenes in good yields. This approach provides a straightforward incorporation of CF3 group into complex molecules for drug discovery.
Modulation of Cathodoluminescence by Surface Plasmons in Silver Nanowires
Authors: Liu Amelia C. Y. , Davis Timothy J. , Coenen Toon , Hari Sangeetha , Voortman Lenard M. , Xu Zhou , Yuan Gangcheng , Ballard Patrycja M. , Funston Alison M. , Etheridge Joanne 
Published: April 2023

AbstractThe waveguide modes in chemically‐grown silver nanowires on silicon nitride substrates are observed using spectrally‐ and spatially‐resolved cathodoluminescence (CL) excited by high‐energy electrons in a scanning electron microscope. The presence of a long‐range, travelling surface plasmon mode modulates the coupling efficiency of the incident electron energy into the nanowires, which is observed as oscillations in the measured CL with the point of excitation by the focused electron beam. The experimental data are modeled using the theory of surface plasmon polariton modes in cylindrical metal waveguides, enabling the complex mode wavenumbers and excitation strength of the long‐range surface plasmon mode to be extracted. The experiments yield insight into the energy transfer mechanisms between fast electrons and coherent oscillations in surface charge density in metal nanowires and the relative amplitudes of the radiative processes excited in the wire by the electron.
Simultaneously Suppressing Shuttle Effect and Dendrite Growth in Lithium–Sulfur Batteries via Building Dual‐Functional Asymmetric‐Cellulose Gel Electrolyte
Authors: Huang Yangze , Cheng Fulin , Cai Chenyang , Fu Yu 
Published: April 2023

AbstractPolysulfides huttling and interfacial instability of Lithium‐anode are the main technical issues hindering commercialization of high‐energy‐density lithium−sulfur batteries. Simply addressing the problem of polysulfide shuttling or lithium dendrite growth can result in safety hazards or short lifespan. To synchronously tackle the aforementioned issues, the authors have designed an asymmetric cellulose gel electrolyte, a defective and ionized UiO66/black phosphorus heterostructure coating layer (Di‐UiO66/BP) and a cationic cellulose gelelectrolyte (QACA). Defective and ionized engineered UiO66 particles significantly enhances performance of UiO66/BP layer in anchoring free polysulfides, promoting smooth and effective polysulfide conversion and expediting the redox kinetics of sulfur cathode, therefore suppressing polysulfide shuttling. QACA electrolyte with numerous cationic groups can interact with anions via electrostatic adsorption, thus enhancing lithium‐ion transference number and contributing to formation of stable solid electrolyte interface to suppress lithium dendrite growth. Owing to the superior performance of QACA/Di‐UiO66/BP, the final cells exhibit outstanding electrochemical performance, presenting high sulfur utilization (1420.1 mAh g−1at 0.1 C), high‐rate capacity (665.4 mAh g−1at 4 C) and long cycle lifespan. This work proposes a strategy of designing asymmetric electrolytes to simultaneously address the challenges in both S‐cathode and Li‐anode, which contributes to advanced Li−S batteries and their practical application.
Dynamic Observation of the Coulomb Explosion and Field Evaporation of a Few‐Layer Graphene Nanoribbon
Authors: Wei Jiake , Xu Qiuhao , Xu Zhi , Wang Wenlong , Meng Sheng , Bai Xuedong 
Published: April 2023

AbstractThe Coulomb explosion and field evaporation are frequently observed physical phenomena for a metallic tip under an external electric field, which can modify the structures of the tip and have broad applications, such as in the atomic‐probe tomography and field ion microscopy. However, the mechanistic comprehending of how they change the structures of the tip and the differences between them are not clear. Here, dynamic observations of Coulomb explosions and field evaporations on the positively biased and charged few‐layer graphene (FLG) nanoribbon inside a transmission electron microscope are reported. By combining the atomic‐scale molecular dynamic simulations, it is shown that the FLG is split into several sheets under Coulomb explosion. It is also observed to break by emitting the carbon ions/segments under the field evaporation. It is further demonstrated that the split and breaking of FLG can be tuned by the shape of the nanoribbon. FLG ribbons with sharp tips have splitting and breaking occur in sequence. FLG with blunt tips break without a split. These results provide a fundamental understanding of Coulomb explosion and field evaporation in graphene nanomaterials and suggest potential methods to engineer graphene‐based nanostructures.
Usnea Acid‐Incorporated Ca2+/Mn2+ Ions Reservoirs for Elevated Ion‐Interference Therapy through Synergetic Biocatalysis and Osmolarity Imbalance
Authors: Zheng Pan , Ding Binbin , Zhu Guoqing , Lin Jun , Li Chunxia 
Published: April 2023

AbstractIon‐interference therapy (IIT) utilizes ions to disturb intracellular biological processes and has been received increasing attention in tumor treatments recently. However, the low therapeutic efficiency still hinders its further biological applications. Herein, via a simple and one‐pot gas diffusion process, polyethylene glycol (PEG)‐modified Mn2+ ions and usnic acid (UA)‐incorporated CaCO3 nanomaterials (PEGCaMnUA) as Ca2+/Mn2+ ions reservoirs are prepared for magnetic resonance imaging (MRI)‐guided UA‐elevated IIT. Among PEGCaMnUA, UA not only increases cytoplasmic Ca2+ ions to amplify Ca2+ overload caused by CaCO3 decomposition, but also enhances Mn2+ ions‐participated Fenton‐like biocatalysis by intracellular H2O2 generation and glutathione consumption. Then increasing the intracellular oxidative stress and decreasing the triphosadenine supply induce apoptosis together, resulting in UA‐boosted IIT. The simple and efficient design of the dual ions reservoirs will contribute to improve the antitumor activity of IIT and further development of calcium‐based nanomaterials in the future.
A Selective Nano Cell Cycle Checkpoint Inhibitor Overcomes Leukemia Chemoresistance
Authors: Sun Jie , Xia Fan , Zhang Shaoqi , Zhang Bo , Guan Yunan , Hu Xi , Xue Pengpeng , Yang Shengfei , Zhou Yan , Ling Daishun , Li Fangyuan 
Published: April 2023

AbstractCell cycle checkpoint activation promotes DNA damage repair, which is highly associated with the chemoresistance of various cancers including acute myeloid leukemia (AML). Selective cell cycle checkpoint inhibitors are strongly demanded to overcome chemoresistance, but remain unexplored. A selective nano cell cycle checkpoint inhibitor (NCCI: citric acid capped ultra‐small iron oxide nanoparticles) that can catalytically inhibit the cell cycle checkpoint of AML to boost the chemotherapeutic efficacy of genotoxic agents is now reported. NCCI can selectively accumulate in AML cells and convert H2O2 to •OH to cleave heat shock protein 90, leading to the degradation of ataxia telangiectasia and Rad3‐related proteinand checkpoint kinase 1, and the subsequent dysfunction of the G2/M checkpoint. Consequently, NCCI revitalizes the anti‐AML efficacy of cytarabine that is previously ineffective both in vitro and in vivo. This study offers new insights into designing selective cell cycle checkpoint inhibitors for biomedical applications.
Viscous Microcapsules as Microbioreactors to Study Mesenchymal Stem/Stromal Cells Osteolineage Commitment
Authors: Ghasemzadeh‐Hasankolaei Maryam , Miranda João M. , Correia Clara R. , Mano João F. 
Published: April 2023

AbstractIt is essential to design a multifunctional well‐controlled platform to transfer mechanical cues to the cells in different magnitudes. This study introduces a platform, a miniaturized bioreactor, which enables to study the effect of shear stress in microsized compartmentalized structures. In this system, the well‐established cell encapsulation system of liquefied capsules (LCs) is used as microbioreactors in which the encapsulated cells are exposed to variable core viscosities to experience different mechanical forces under a 3D dynamic culture. The LC technology is joined with electrospraying to produce such microbioreactors at high rates, thus allowing the application of microcapsules for high‐throughput screening. Using this platform for osteogenic differentiation as an example, shows that microbioreactors with higher core viscosity which produce higher shear stress lead to significantly higher osteogenic characteristics. Moreover, in this system the forces experienced by cells in each LC are simulated by computational modeling. The maximum wall shear stress applied to the cells inside the bioreactor with low, and high core viscosity environment is estimated to be 297 and 1367 mPa, respectively, for the experimental setup employed. This work outlines the potential of LC microbioreactors as a reliable in vitro customizable platform with a wide range of applications.
EdgeAuth: An intelligent token‐based collaborative authentication scheme
Authors: Jiang Xutong , Dou Ruihan , He Qiang , Zhang Xuyun , Dou Wanchun 
Published: April 2023

AbstractEdge computing is regarded as an extension of cloud computing that brings computing and storage resources to the network edge. For some Industrial Internet of Things (IIoT) applications such as supply‐chain supervision and collaboration, Internet of Vehicles, real‐time video analysis and so forth, users should be authenticated before visiting the geographically distributed edge servers. Limited by the considerable latency between the cloud and edge servers, and the limited capacity of edge servers, it is infeasible to copy the authentication method from cloud servers when users are authenticated in edge servers. In view of this challenge, this paper proposes a novel token‐based authentication scheme, named EdgeAuth, that enables fast edge user authentication through collaboration among cloud servers and edge servers. Under the EdgeAuth scheme, edge servers can rapidly verify the credentials of users who have been authenticated by the cloud server. EdgeAuth can also protect users from a series of authentication attacks, for example, the replay attack, DoS attack and man‐in‐the‐middle attack. The results of experiments conducted on a simulated edge computing environment validate the usefulness of EdgeAuth through a comparison in latency and throughput against two baseline schemes.
Effect of Inulin on Thermal Properties, Pasting, Rheology, and In Vitro Digestion of Potato Starch
Authors: Ji Xiaolong , Chen Jin , Jin Xueyuan , Chen Jiaxin , Ding Yongdan , Shi Miaomiao , Guo Xundan , Yan Yizhe 
Published: April 2023

AbstractIn this study, different concentrations of natural inulin (IN) are compounded with potato starch (PoS) to prepare an inulin‐potato starch (PoS‐IN) compound system, and the physical and chemical properties of the compound system such as pasting, rheology, and digestion are investigated. According to the findings, the complex system's viscosity, breakdown, and setback are greatly reduced. The addition of IN also prevents the complex system from being pasted and increases the stability of the PoS. The gel structure of the PoS‐IN complex gradually changes from solid‐like to liquid‐like. In addition, the in vitro digestion test results show that the content of resistant starch in the complex system increases with the increase in IN concentration. This study can provide guidance for the development and application of IN‐starch‐based food products, which can increase the nutritional value of traditional PoS‐based food products.