bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Semi‐Analytical (Inertial) Solution for Determining Permeability of Highly Pervious Porous Materials Using the Two‐Reservoir Laboratory Setup
Authors: Stanić Filip , Govedarica Ognjen , Jaćimović Nenad , Lekić Branislava , Ranđelović Anja 
Published: June 2023

AbstractTwo conventional experimental procedures for determination of the water permeability of saturated porous medium are the constant and the falling head permeability tests. The first one is more applicable on more permeable materials where the outflow from the sample is measured at variety of constant water heads, while the second one is more convenient for low permeable materials, utilizing the continuous measurements of the water head falling due to filtration through the saturated sample. However, neither of the two is useful for materials of high permeability and large cross‐sectional area. The constant head permeability test faces technical issues since a significant and continuous water discharge is required, while the falling head permeability test has limitations due to neglection of the Forchheimer's high‐velocity flow through the sample, but also the influence of inertia on the fluid mass. Here we proposed an approach for determination of the water permeability of saturated porous medium based on the agreement between the measured water level change in two connected reservoirs containing a porous sample and the new semi‐analytical expression describing that change by accounting for the mentioned theoretical deficiencies. This efficient approach has been tested on four pervious paver samples, and results showed satisfactory agreement with the constant head permeability data. It has been also confirmed the proposed semi‐analytical solution is more accurate than the falling head permeability approach in case of highly pervious materials, while for low permeable materials it reduces to the conventional approach.
Rapid Aggregation and Dissolution of Organic Aerosols in Liquid Methane on Titan
Authors: Hirai Eito , Sekine Yasuhito , Zhang Naizhong , Noda Natsumi , Tan Shuya , Takahashi Yoshio , Kagi Hiroyuki 
Published: June 2023

AbstractComplex organic aerosols in the upper atmosphere of Saturn's moon Titan reach the troposphere and surface, where a methane (CH4)‐based hydrological cycle occur. Previous studies have assumed no interactions between organic aerosols and liquid CH4, although the dissolution of low‐molecular‐weight photochemical products in liquid CH4 has been considered. Here we report experimental results of soaking a laboratory analog (so‐called tholin) of Titan's organic aerosols in liquid CH4 at 93–98 K for several hours and then evaporating the liquid, simulating wet–dry cycling on Titan. After wet–dry cycling, residual tholin particles form aggregates through cementation. Solid evaporitic deposits formed by evaporation of interacted liquid contain nitrogen‐bearing aromatics, suggesting selective dissolution of aromatics. Our results suggest that organic aerosols or high‐molecular‐weight compounds adsorbed on them partly dissolve in liquid CH4 on Titan, even during short‐term wetting events, promoting the growth of aerosols to dune particles via aggregation and providing aromatics to evaporites.
Possible Linkage Between Winter Extreme Low Temperature Over Western‐Central China and Autumn Sea Ice Loss
Authors: Ding Shuoyi , Wu Bingyi , Chen Wen , Graf Hans‐F. , Zhang Xuanwen 
Published: June 2023

AbstractBased on reanalysis datasets and sea‐ice sensitivity experiments, this study has pointed out that the autumn sea ice loss in East Siberian‐Chukchi‐Beaufort (EsCB) Seas significantly increases the frequency of winter extreme low temperature over western‐central China. Autumn sea ice loss warms the troposphere and generates anticyclonic anomaly over the Arctic region 1 month later. Under the effects of synoptic eddy‐mean flow interaction and anomalous upward propagated planetary wave 2, the Arctic anticyclonic anomaly strengthens and develops toward Greenland‐Northern Europe, accompanied by a weakened stratospheric polar vortex. In winter, following intra‐seasonal downward propagation of stratospheric anomalies, the Northern European positive geopotential height anomalies enhance and expand downstream within 7 days, favoring Arctic cold air east of Novaya Zemlya southward (the hyperpolar path) accumulating in Siberia around Lake Baikal. In the subsequent 2–3 days, these cold anomalies rapidly intrude western‐central China and induce abrupt sharp cooling, thus more frequent extreme low temperature there. In contrast, the role of autumn Barents‐Kara (BK) sea ice loss exhibits quite different features, mainly favoring northwestern, northeastern and eastern China to experience increased frequency of extreme low temperature in winter.
Delivery mechanism can enhance probiotic activity against honey bee pathogens
Authors: Daisley Brendan A , Pitek Andrew P , Torres Christina , Lowery Robin , Adair Bethany A , Al Kait F , Niño Bernardo , Burton Jeremy P , Allen-Vercoe Emma , Thompson Graham J , Reid Gregor , Niño Elina 
Published: June 2023

Abstract
Managed honey bee (Apis mellifera) populations play a crucial role in supporting pollination of food crops but are facing unsustainable colony losses, largely due to rampant disease spread within agricultural environments. While mounting evidence suggests that select lactobacilli strains (some being natural symbionts of honey bees) can protect against multiple infections, there has been limited validation at the field-level and few methods exist for applying viable microorganisms to the hive. Here, we compare how two different delivery systems—standard pollen patty infusion and a novel spray-based formulation—affect supplementation of a three-strain lactobacilli consortium (LX3). Hives in a pathogen-dense region of California are supplemented for 4 weeks and then monitored over a 20-week period for health outcomes. Results show both delivery methods facilitate viable uptake of LX3 in adult bees, although the strains do not colonize long-term. Despite this, LX3 treatments induce transcriptional immune responses leading to sustained decreases in many opportunistic bacterial and fungal pathogens, as well as selective enrichment of core symbionts including Bombilactobacillus, Bifidobacterium, Lactobacillus, and Bartonella spp. These changes are ultimately associated with greater brood production and colony growth relative to vehicle controls, and with no apparent trade-offs in ectoparasitic Varroa mite burdens. Furthermore, spray-LX3 exerts potent activities against Ascosphaera apis (a deadly brood pathogen) likely stemming from in-hive dispersal differences, whereas patty-LX3 promotes synergistic brood development via unique nutritional benefits. These findings provide a foundational basis for spray-based probiotic application in apiculture and collectively highlight the importance of considering delivery method in disease management strategies.
Developmental vitamin D-deficiency produces autism-relevant behaviours and gut-health associated alterations in a rat model
Authors: Tamang Man Kumar , Ali Asad , Pertile Renata Nedel , Cui Xiaoying , Alexander Suzy , Nitert Marloes Dekker , Palmieri Chiara , Eyles Darryl 
Published: June 2023

AbstractDevelopmental vitamin D (DVD)-deficiency is an epidemiologically established risk factor for autism. Emerging studies also highlight the involvement of gut microbiome/gut physiology in autism. The current study aims to examine the effect of DVD-deficiency on a broad range of autism-relevant behavioural phenotypes and gut health. Vitamin D deficient rat dams exhibited altered maternal care, DVD-deficient pups showed increased ultrasonic vocalizations and as adolescents, social behaviour impairments and increased repetitive self-grooming behaviour. There were significant impacts of DVD-deficiency on gut health demonstrated by alterations to the microbiome, decreased villi length and increased ileal propionate levels. Overall, our animal model of this epidemiologically validated risk exposure for autism shows an expanded range of autism-related behavioural phenotypes and now alterations in gut microbiome that correlate with social behavioural deficits raising the possibility that DVD-deficiency induced ASD-like behaviours are due to alterations in gut health.
Witnessing light-driven entanglement using time-resolved resonant inelastic X-ray scattering
Authors: Hales Jordyn , Bajpai Utkarsh , Liu Tongtong , Baykusheva Denitsa R. , Li Mingda , Mitrano Matteo , Wang Yao 
Published: June 2023

AbstractCharacterizing and controlling entanglement in quantum materials is crucial for the development of next-generation quantum technologies. However, defining a quantifiable figure of merit for entanglement in macroscopic solids is theoretically and experimentally challenging. At equilibrium the presence of entanglement can be diagnosed by extracting entanglement witnesses from spectroscopic observables and a nonequilibrium extension of this method could lead to the discovery of novel dynamical phenomena. Here, we propose a systematic approach to quantify the time-dependent quantum Fisher information and entanglement depth of transient states of quantum materials with time-resolved resonant inelastic x-ray scattering. Using a quarter-filled extended Hubbard model as an example, we benchmark the efficiency of this approach and predict a light-enhanced many-body entanglement due to the proximity to a phase boundary. Our work sets the stage for experimentally witnessing and controlling entanglement in light-driven quantum materials via ultrafast spectroscopic measurements.
Hadaean to Palaeoarchaean stagnant-lid tectonics revealed by zircon magnetism
Authors: Tarduno John A. , Cottrell Rory D. , Bono Richard K. , Rayner Nicole , Davis William J. , Zhou Tinghong , Nimmo Francis , Hofmann Axel , Jodder Jaganmoy , Ibañez-Mejia Mauricio , Watkeys Michael K. , Oda Hirokuni , Mitra Gautam 
Published: June 2023

AbstractPlate tectonics is a fundamental factor in the sustained habitability of Earth, but its time of onset is unknown, with ages ranging from the Hadaean to Proterozoic eons1–3. Plate motion is a key diagnostic to distinguish between plate and stagnant-lid tectonics, but palaeomagnetic tests have been thwarted because the planet’s oldest extant rocks have been metamorphosed and/or deformed4. Herein, we report palaeointensity data from Hadaean-age to Mesoarchaean-age single detrital zircons bearing primary magnetite inclusions from the Barberton Greenstone Belt of South Africa5. These reveal a pattern of palaeointensities from the Eoarchaean (about 3.9 billion years ago (Ga)) to Mesoarchaean (about 3.3 Ga) eras that is nearly identical to that defined by primary magnetizations from the Jack Hills (JH; Western Australia)6,7, further demonstrating the recording fidelity of select detrital zircons. Moreover, palaeofield values are nearly constant between about 3.9 Ga and about 3.4 Ga. This indicates unvarying latitudes, an observation distinct from plate tectonics of the past 600 million years (Myr) but predicted by stagnant-lid convection. If life originated by the Eoarchaean8, and persisted to the occurrence of stromatolites half a billion years later9, it did so when Earth was in a stagnant-lid regime, without plate-tectonics-driven geochemical cycling.
High-brightness scalable continuous-wave single-mode photonic-crystal laser
Authors: Yoshida Masahiro , Katsuno Shumpei , Inoue Takuya , Gelleta John , Izumi Koki , De Zoysa Menaka , Ishizaki Kenji , Noda Susumu 
Published: June 2023

AbstractRealizing large-scale single-mode, high-power, high-beam-quality semiconductor lasers, which rival (or even replace) bulky gas and solid-state lasers, is one of the ultimate goals of photonics and laser physics. Conventional high-power semiconductor lasers, however, inevitably suffer from poor beam quality owing to the onset of many-mode oscillation1,2, and, moreover, the oscillation is destabilized by disruptive thermal effects under continuous-wave (CW) operation3,4. Here, we surmount these challenges by developing large-scale photonic-crystal surface-emitting lasers with controlled Hermitian and non-Hermitian couplings inside the photonic crystal and a pre-installed spatial distribution of the lattice constant, which maintains these couplings even under CW conditions. A CW output power exceeding 50 W with purely single-mode oscillation and an exceptionally narrow beam divergence of 0.05° has been achieved for photonic-crystal surface-emitting lasers with a large resonant diameter of 3 mm, corresponding to over 10,000 wavelengths in the material. The brightness, a figure of merit encapsulating both output power and beam quality, reaches 1 GW cm−2 sr−1, which rivals those of existing bulky lasers. Our work is an important milestone toward the advent of single-mode 1-kW-class semiconductor lasers, which are expected to replace conventional, bulkier lasers in the near future.
Single-photon absorption and emission from a natural photosynthetic complex
Authors: Li Quanwei , Orcutt Kaydren , Cook Robert L. , Sabines-Chesterking Javier , Tong Ashley L. , Schlau-Cohen Gabriela S. , Zhang Xiang , Fleming Graham R. , Whaley K. Birgitta 
Published: June 2023

AbstractPhotosynthesis is generally assumed to be initiated by a single photon1–3 from the Sun, which, as a weak light source, delivers at most a few tens of photons per nanometre squared per second within a chlorophyll absorption band1. Yet much experimental and theoretical work over the past 40 years has explored the events during photosynthesis subsequent to absorption of light from intense, ultrashort laser pulses2–15. Here, we use single photons to excite under ambient conditions the light-harvesting 2 (LH2) complex of the purple bacterium Rhodobacter sphaeroides, comprising B800 and B850 rings that contain 9 and 18 bacteriochlorophyll molecules, respectively. Excitation of the B800 ring leads to electronic energy transfer to the B850 ring in approximately 0.7 ps, followed by rapid B850-to-B850 energy transfer on an approximately 100-fs timescale and light emission at 850–875 nm (refs. 16–19). Using a heralded single-photon source20,21 along with coincidence counting, we establish time correlation functions for B800 excitation and B850 fluorescence emission and demonstrate that both events involve single photons. We also find that the probability distribution of the number of heralds per detected fluorescence photon supports the view that a single photon can upon absorption drive the subsequent energy transfer and fluorescence emission and hence, by extension, the primary charge separation of photosynthesis. An analytical stochastic model and a Monte Carlo numerical model capture the data, further confirming that absorption of single photons is correlated with emission of single photons in a natural light-harvesting complex.
Silicon isotope constraints on terrestrial planet accretion
Authors: Onyett Isaac J. , Schiller Martin , Makhatadze Georgy V. , Deng Zhengbin , Johansen Anders , Bizzarro Martin 
Published: June 2023

AbstractUnderstanding the nature and origin of the precursor material to terrestrial planets is key to deciphering the mechanisms and timescales of planet formation1. Nucleosynthetic variability among rocky Solar System bodies can trace the composition of planetary building blocks2–5. Here we report the nucleosynthetic composition of silicon (μ30Si), the most abundant refractory planet-building element, in primitive and differentiated meteorites to identify terrestrial planet precursors. Inner Solar System differentiated bodies, including Mars, record μ30Si deficits of −11.0 ± 3.2 parts per million to −5.8 ± 3.0 parts per million whereas non-carbonaceous and carbonaceous chondrites show μ30Si excesses from 7.4 ± 4.3 parts per million to 32.8 ± 2.0 parts per million relative to Earth. This establishes that chondritic bodies are not planetary building blocks. Rather, material akin to early-formed differentiated asteroids must represent a major planetary constituent. The μ30Si values of asteroidal bodies correlate with their accretion ages, reflecting progressive admixing of a μ30Si-rich outer Solar System material to an initially μ30Si-poor inner disk. Mars’ formation before chondrite parent bodies is necessary to avoid incorporation of μ30Si-rich material. In contrast, Earth’s μ30Si composition necessitates admixing of 26 ± 9 per cent of μ30Si-rich outer Solar System material to its precursors. The μ30Si compositions of Mars and proto-Earth are consistent with their rapid formation by collisional growth and pebble accretion less than three million years after Solar System formation. Finally, Earth’s nucleosynthetic composition for s-process sensitive (molybdenum and zirconium) and siderophile (nickel) tracers are consistent with pebble accretion when volatility-driven processes during accretion and the Moon-forming impact are carefully evaluated.
Psychedelics reopen the social reward learning critical period
Authors: Nardou Romain , Sawyer Edward , Song Young Jun , Wilkinson Makenzie , Padovan-Hernandez Yasmin , de Deus Júnia Lara , Wright Noelle , Lama Carine , Faltin Sehr , Goff Loyal A. , Stein-O’Brien Genevieve L. , Dölen Gül 
Published: June 2023

AbstractPsychedelics are a broad class of drugs defined by their ability to induce an altered state of consciousness1,2. These drugs have been used for millennia in both spiritual and medicinal contexts, and a number of recent clinical successes have spurred a renewed interest in developing psychedelic therapies3–9. Nevertheless, a unifying mechanism that can account for these shared phenomenological and therapeutic properties remains unknown. Here we demonstrate in mice that the ability to reopen the social reward learning critical period is a shared property across psychedelic drugs. Notably, the time course of critical period reopening is proportional to the duration of acute subjective effects reported in humans. Furthermore, the ability to reinstate social reward learning in adulthood is paralleled by metaplastic restoration of oxytocin-mediated long-term depression in the nucleus accumbens. Finally, identification of differentially expressed genes in the ‘open state’ versus the ‘closed state’ provides evidence that reorganization of the extracellular matrix is a common downstream mechanism underlying psychedelic drug-mediated critical period reopening. Together these results have important implications for the implementation of psychedelics in clinical practice, as well as the design of novel compounds for the treatment of neuropsychiatric disease.
Breviscapine regulates the proliferation, migration, invasion, and apoptosis of colorectal cancer cells via the PI3K/AKT pathway
Authors: Niu Pengfei , Liu Feng , Lei Fuming , Peng Jisheng , Wang Yanzhao , Zhao Jun , Gao Zhaoya , Gao Qingkun , Gu Jin 
Published: June 2023

AbstractColorectal cancer (CRC) is ranked as one of the most common malignancies with a high death rate. It has been discovered that breviscapine can alter the progression and development of various cancers. Nevertheless, the function and mechanisms of breviscapine in CRC progression have not yet been described. The cell proliferation capacity of HCT116 and SW480 cells was assessed using the CCK-8 and EdU assays. Cell apoptosis was tested through flow cytometry, and cell migration and invasion were examined using the transwell assay. Moreover, protein expression was examined through a western blot. Tumor weight and volume were assessed using the nude mice in vivo assay, and the Ki-67 protein expression was verified through the IHC assay. This study discovered that an increased dose of breviscapine (0, 12.5, 25, 50, 100, 200, and 400 μM) gradually reduced cell proliferation and increased apoptosis in CRC. Additionally, breviscapine restricted the migration and invasion CRC cells. Moreover, it was revealed that breviscapine inactivated the PI3K/AKT pathway and inhibited CRC progression. Finally, an in vivo assay demonstrated that breviscapine restrained tumor growth in vivo. It affected the CRC cells’ proliferation, migration, invasion, and apoptosis through the PI3K/AKT pathway. This discovery may offer new insights into CRC treatment.
Millimeter-wave planar antenna array augmented with a low-cost 3D printed dielectric polarizer for sensing and internet of things (IoT) applications
Authors: Al-Alem Yazan , Sifat Syed M. , Antar Yahia M. M. , Kishk Ahmed A. 
Published: June 2023

AbstractA unique high gain antenna array with a 3D-printed dielectric polarizer is proposed. The packaging of the antenna array feeding structure is eliminated by aggregating the feeding network in between the antenna elements. This has a significant advantage in maintaining neat and symmetric radiation characteristics with low cross-polarization levels. The proposed structure combines two elements in one feeding point to reduce the array distribution feeding points of a 4 × 4 antenna array from 16 to 8 points. The proposed antenna array structure is extremely low in cost and can be used as either a linearly or circularly polarized one. The antenna array achieves a gain of 20 dBi/dBiC in both scenarios. The matching bandwidth is 4.1%, and the 3-dB Axial Ratio (AR) bandwidth is 6%. The antenna array uses a single substrate layer without the need for any vias. The proposed antenna array suits well various applications at 24 GHz, while maintaining high performance metrics, and low cost. The antenna array can be easily integrated with transceivers due to the use of printed microstrip line technology.
Open decortication for patients presenting with stage III tuberculous empyema with low density lines on CT imaging
Authors: Liu Xiaoyu , Wang Xuan , Sheng Jian , Jiang Yuhui , Li Li , Dai Xiyong 
Published: June 2023

AbstractTo explore the influence of CT findings on the optimal timing of open decorticationin patients with stage III tuberculous empyema. A total of 80 patients with stage III tuberculous empyema who had undergone open decortications were recruited; 44 patients had chest CT findings indicating low-density lines, while 36 patients did not show this imaging finding. Demographic data, perioperative data and preoperative and postoperative chest CT images were collected. In the low-density line group, the duration of disease (P = 0.0030) and the preoperative anti-tuberculosis time (P = 0.0016) were longer than those of the group without low-density lines, and the ESR (P = 0.0218), CRP (P = 0.0027) and leukocyte count (P = 0.0339) were lower in the low-density line group. Additionally, in the median operative time (P = 0.0003), intraoperative blood loss (P < 0.0001), volume of catheter drainage during 48 h after operation (P = 0.0067), chest tube duration (P < 0.0001), and length of hospital stay (P = 0.0154) were significantly lower in the low-density line group than in the group without low-density lines. A total of 88.64% of participants in the low-density line group showed hyperplasia with hyaline degeneration in pathological examination, which was observed only in 41.67% of patients without low-density lines. In addition, gaseous necrosis was considerably higher in patients without a low-density line (P = 0.004), while the low-density line group had a higher rate of treatment success (P < 0.05). Patients with stage III tuberculous empyema presenting with low-density lines around the thickened fibrous pleural rind on preoperative CT imaging may be good candidates for open decortication.