bluuebunny/crossref_metadata_2025_split huggingface dataset:
Embedding Dimensions of Simplicial Complexes on Few Vertices
Authors: Frick Florian , Hu Mirabel , Scheel Verity , Simon Steven 
Published: March 2023

AbstractWe provide a simple characterization of simplicial complexes on few vertices that embed into the d-sphere. Namely, a simplicial complex on $$d+3$$

d
+
3

vertices embeds into the d-sphere if and only if its non-faces do not form an intersecting family. As immediate consequences, we recover the classical van Kampen–Flores theorem and provide a topological extension of the Erdős–Ko–Rado theorem. By analogy with Fáry’s theorem for planar graphs, we show in addition that such complexes satisfy the rigidity property that continuous and linear embeddability are equivalent.
Multi-stage metal enrichment and formation of gold mineralization in black shales: the role of high heat flow in a rift setting
Authors: Pašava Jan , Ackerman Lukáš , Žák Jiří , Svojtka Martin , Magna Tomáš , Pour Ondřej , Trubač Jakub , Veselovský František 
Published: March 2023

Abstract
Black shales may serve as an important source of metals such as Co, Ni, or As, largely due to anoxic to euxinic conditions in association with high concentrations of sulfur leading to efficient scavenging and transport of metals from seawater into the seafloor sediment. We report on an unusual type of Au mineralization newly discovered in Ediacaran trench-slope black shales in the Bohemian Massif, Czech Republic. The Au enrichment is related to the formation of a quartz–sulfide vein system and a progressive evolution of ore-forming fluids with decreasing temperature, from Sb- to As-rich to final precipitation of native gold from silica and Au-bearing low-temperature hydrothermal colloidal solutions. The hydrothermal nature of these solutions is also documented by Li contents and isotope compositions which differ markedly between barren black shales and those carrying significant late-stage quartz-rich veins. The structural relationships and orientation of the associated quartz veins point to a close connection between vein emplacement and high heat flow in response to Ordovician rifting, and breakup of the northern margin of Gondwana, and opening of the Rheic Ocean. This triggered metal and sulfur remobilization, including Au, from the associated Neoproterozoic–Cambrian volcanosedimentary successions. The documented Au mineralization and its association with the Ordovician rift-related magmatic activity is different from the widespread Variscan Au occurrences in the Bohemian Massif. Our study thus provides a new genetic model potentially important for future exploration of Au also in other terrains underlain by a rifted Cadomian basement.
Video analysis of Achilles tendon ruptures in professional male football (soccer) reveals underlying injury patterns and provides strategies for injury prevention
Authors: Hoenig Tim , Gronwald Thomas , Hollander Karsten , Klein Christian , Frosch Karl-Heinz , Ueblacker Peter , Rolvien Tim 
Published: March 2023

Abstract
Purpose
In professional football (soccer), Achilles tendon ruptures are severe injuries. Video analysis promotes a better understanding of the underlying situational and biomechanical patterns, and provides a roadmap for future research to improve the management and prevention of Achilles tendon ruptures. The purpose of this study was to identify injury patterns contributing to acute Achilles tendon ruptures in professional male football players.

Methods
Professional male football players with an acute Achilles tendon rupture were identified using an online database. For every in-competition injury, the corresponding football match was detected. Video footage of the injury was accessed using Wyscout.com or publicly available video databases. Situational patterns and injury biomechanics of the injury frame were independently analysed by two reviewers using a standardised checklist and a motion analysis software. Finally, consensus was reached to describe the main injury patterns of Achilles tendon ruptures in professional male football players.

Results
The search identified video footage of 80 Achilles tendon ruptures in 78 players. Most injuries (94%) occurred through indirect or non-contact mechanisms. The kinematic analysis revealed characteristic joint positions at the time of injury consisting of hip extension, knee extension, ankle dorsiflexion, foot abduction, and foot pronation in most cases. The underlying direction of movement was from flexion to extension (knee) and from plantarflexion to dorsiflexion (ankle). Player actions identified as main injury patterns were stepping back (26%), landing (20%), running/sprinting (18%), jumping (13%), and starting (10%).

Conclusion
Most Achilles tendon ruptures in professional male football players are closed-chain indirect or non-contact injuries. Sudden loading to the plantarflexor musculotendinous unit remains to be the main component for most cases. By achieving a better understanding of underlying injury mechanisms, this study provides new strategies for the prevention of Achilles tendon ruptures.

Level of evidence
Level IV.
The étale symmetric Künneth theorem
Authors: Hoyois Marc 
Published: March 2023

AbstractLet k be an algebraically closed field, $$l\ne {{\,\textrm{char}\,}}k$$

l
≠

char

k

a prime number, and X a quasi-projective scheme over k. We show that the étale homotopy type of the dth symmetric power of X is $$\textbf{Z}/l$$

Z
/
l

-homologically equivalent to the dth strict symmetric power of the étale homotopy type of X. We deduce that the $$\textbf{Z}/l$$

Z
/
l

-local étale homotopy type of a motivic Eilenberg–Mac Lane space is an ordinary Eilenberg–Mac Lane space.
Balloon Eustachian tuboplasty for obstructive Eustachian tube dysfunction: retrospective multicentre cohort study of 248 patients
Authors: Sandoval Marta , Navarro Juan-J , Martínez-Beneyto Paz , Herrera Mayte , Alfaro Jorge , López Felipe , Marco Jaime , Plaza Guillermo 
Published: March 2023

Abstract
Objective
To present the results after balloon eustachian tuboplasty (BET) in patients with obstructive Eustachian tube dysfunction (OETD) grouped up into: baro-challenge, chronic serous otitis media and adhaesive otitis media.

Methods
A retrospective study was carried out on patients who underwent BET surgery. As outcome measures, otoscopy, tympanometry, Eustachian tube dysfunction questionnaire-7 (ETDQ-7) and ability to perform the Valsalva manoeuvre were recorded at baseline and at 3, 12 and 24 months after BET. A p value of 0.05 was used to indicate a statistically significant difference for all statistical tests.

Results
Three hundred and nineteen ears (248 patients) were included with a 3-month follow-up, 272 ears had a 12-month follow-up, and 171 ears had 24-month follow-up. Globally, a statistical significance improvement in all groups in all outcome measures was found. According to BET indication, in the baro-challenge group, there was no improvement in otoscopy, but ETDQ-7, Valsalva manoeuvre and tympanogram improved significantly. In the chronic serous otitis media group, otoscopy, ETDQ-7 and Valsalva manoeuvre were significantly improved in all the three timelines, including the avoidance of a new transtympanic tube after the BET in over 80% of cases. In the adhaesive otitis media group, Valsalva manoeuvre improved significantly, ETDQ-7 decreased and tympanogram improved but not significantly. Few mild complications were reported.

Conclusions
BET is an effective method for the treatment of OETD in all etiologic groups. The greatest benefit was observed in patients with baro-challenge. A long-term follow-up is recommended since the benefit seems to increase over time.
The use of isCGM leads to marked reduction in severe hypoglycemia requiring emergency medical service or hospital admission and diabetic ketoacidosis in adult type 1 diabetes patients
Authors: Mustonen Jyrki , Rautiainen Päivi , Lamidi Marja-Leena , Lavikainen Piia , Martikainen Janne , Laatikainen Tiina 
Published: March 2023

Abstract
Aims
To determine the effect of the use of intermittently scanned continuous glucose monitoring (isCGM) on acute diabetes-related complications in adult type 1 diabetes patients.

Methods
Six hundred and forty-two adult type 1 diabetes patients with isCGM were identified from electronic health records in Siun sote region in Eastern Finland. A retrospective real-world analysis was conducted combining hospital admission and prehospital emergency service data to compare incidences of hypoglycemia requiring emergency medical support (EMS) involvement or hospital admission and diabetic ketoacidosis (DKA) before and after the start of isCGM. Data were collected from January 2015 to April 2020. Primary outcome was the rate of hypoglycemia requiring EMS involvement or hospital admission and DKA events. HbA1c was recorded at the start of isCGM and was compared with the last known HbA1c during the use of isCGM. The isCGM used in the study did not contain alarm functions.

Results
Altogether 220 hypoglycemic events were identified during the study period. Incidence rate of hypoglycemic events decreased after the start of isCGM (72 events, incidence rate 50 events/1000 person-years) compared with the time before the start (148 events, incidence rate 76 events/1000 person-years) (p = 0.043). The incidence rate of DKA decreased after the start of isCGM compared with time before isCGM use (4 and 15 events/1000 person-years, respectively; p = 0.002). The change in mean HbA1c was − 0.28% (− 3.1 mmol/mol) between baseline and the last HbA1c measurement (p < 0.001).

Conclusions
In addition to lowering HbA1c in type 1 diabetes patients, isCGM is also effective in preventing acute diabetes-related complications such as hypoglycemia requiring EMS involvement or hospital admission and DKA.
A characterization of the symmetry groups of mono-monostatic convex bodies
Authors: Domokos Gábor , Lángi Zsolt , Várkonyi Péter L. 
Published: March 2023

AbstractAnswering a question of Conway and Guy (SIAM Rev. 11:78-82, 1969), Lángi (Bull. Lond. Math. Soc. 54: 501-516, 2022) proved the existence of a monostable polyhedron with n-fold rotational symmetry for any $$n \ge 3$$

n
≥
3

, and arbitrarily close to a Euclidean ball. In this paper we strengthen this result by characterizing the possible symmetry groups of all mono-monostatic smooth convex bodies and convex polyhedra. Our result also answers a stronger version of the question of Conway and Guy, asked in the above paper of Lángi.
Anhaltend spannend – das zu kurze Zungenband, Teil 2
Authors: Guóth-Gumberger Márta , Karall Daniela 
Published: March 2023

ZusammenfassungDie Zunge hat eine zentrale Aufgabe bei vielerlei Aufgaben. Stillen, angemessene Ernährung und altersgemäßer Gewichtsverlauf sind einige davon – und wichtige Anliegen in der Pädiatrie. Auch bei Problemen mit Essen, Aussprache, Schlucken oder Zahnstellung kann eine eingeschränkte Zungenbeweglichkeit durch ein zu kurzes Zungenband eine Rolle spielen. Die ausgeprägte Variante des zu kurzen Zungenbandes, das Frenulum linguae breve anterior (zu kurzes Zungenband mit Ansatz an der Zungenspitze), ist sichtbar und wird meist behandelt; seltener ist die posteriore Variante (zu kurzes Zungenband mit Ansatz hinter der Zungenspitze), bei der die Zungenspitze frei ist und keine Einkerbung zeigt. Die Auseinandersetzung mit der Anatomie der Strukturen in der Mundhöhle, mit den unterschiedlichen Möglichkeiten der Beurteilung der Funktion der Zunge und der Frenotomie als Behandlung sollen die Entscheidung zu einer geeigneten, individuellen Therapie ermöglichen. Bleibt ein zu kurzes Zungenband unerkannt, zeigen die Maßnahmen oft nicht die erwünschte Wirkung. Daher ist es essenziell zu erkennen, wann eine Behandlung sinnvoll ist, damit das Ergebnis – nämlich eine verbesserte Beweglichkeit der Zunge für die erforderlichen Funktionen – erreicht wird.In dieser dreiteiligen Serie zum Thema zu kurzes Zungenband wird ein vertiefter Überblick über das Thema geschaffen, insbesondere über den Zusammenhang mit Stillen, Ernährung, Gewichtsverlauf, Sprache und Zahnstellung. Teil 1 (Pädiatrie und Pädologie 2023‑1) befasste sich mit der Beurteilung des zu kurzen Zungenbandes, mit Hinweis auf die Notwendigkeit eines multifaktoriellen Beurteilungskonzeptes, das Vor- und Nachsorge sowie die Zusammenarbeit mit anderen Fachkräften und die Beschäftigung mit erstellten Fotos (und Videos) berücksichtigt. Teil 2, der in dieser Folge von Pädiatrie und Pädologie erscheint, behandelt die Behandlungsmethoden des zu kurzen Zungenbandes. Teil 3 wird sich mit den Problemfeldern bezüglich der Behandlungsmethoden bei zu kurzem Zungenband (und Lippenband) und in der Nachbehandlung des zu kurzen Zungenbandes befassen.Die Schritte der Beurteilung, Indikationsstellung/Diagnose und Therapie sowie die Nachsorge werden evidenzbasiert besprochen, mit dem Ziel, dass die Betroffenen und deren Familien die benötigte Hilfe kompetent und zeitgerecht erhalten.
The effects of temporally distinct light pollution from ships on nocturnal colony attendance in a threatened seabird
Authors: Austad Martin , Oppel Steffen , Crymble James , Greetham Hannah R. , Sahin Dilek , Lago Paulo , Metzger Benjamin J. , Quillfeldt Petra 
Published: March 2023

AbstractThe ecological effects from artificial light are complex and can affect species and life-stages differently. Ships are a dynamic source of light pollution, often brightly lit and temporarily increasing light levels in otherwise relatively dark areas. Because several nocturnal seabird species display reduced activity and avoidance of natural or artificial light, we expect that bright vessel lights may affect colony attendance patterns. Here, we test whether the presence of ships in front of coastal cliffs affects colony attendance in the Yelkouan Shearwater (Puffinus yelkouan). Ship presence at the site was obtained from an automatic identification system database, and a data logger measured light levels at the colony autonomously for four breeding seasons (2017–2020). Moreover, a Radio Frequency Identification (RFID) system was deployed at a cavernous colony entrance to register arrivals and departures of shearwaters. Direct illumination from ships increased cliff face brightness, and colony attendance was significantly reduced in brighter conditions. Ship presence reduced the number of shearwaters entering the colony per hour by a mean of 18% (SD ± 24). Disruption of natural attendance patterns is likely to have short- and long-term effects on breeding success, physiological condition, and colony viability. Therefore, we propose mitigation measures to reduce the impact from commercial shipping on burrow-nesting seabirds. Local regulations are necessary for colony-specific impact reduction, while incorporation of measures such as black-out blinds, fixture shielding and maximum brightness limits into international conventions can have additional far-reaching benefits.
Evaluating the utilization of technological factors to promote e-commerce adoption in small and medium enterprises
Authors: Hossain Md Billal , Dewan Nargis , Senin Aslan Amat , Illes Csaba Balint 
Published: March 2023

Abstract
This study examined the technological factor's utilization to promote the e-commerce in small and medium sized enterprises in Bangladesh. The technological factors are, Information and communication adoption, Internet connectivity, and Business data management. The e-commerce adoption factors involve the strategic innovation, research and development activity, and Productivity growth. The electronic commerce is being widely adopted in Bangladesh in the time of covid-19 pandemic. In the adoption of e-commerce, prominent factors are the internet connectivity, which plays a major role and Business data management which has equal importance for SMEs. SMEs have limited access to data as compared to multinational industries. However, the data has equal importance for multinational and SMEs to improve the e-commerce business. The research collects data from 115 SMEs from Bangladesh relating to different fields. The random selection method has been advised to collect data from SMEs aged not less than five years. The data collected for this research is through the interested parties of small and medium sized enterprises in Bangladesh. The data of the research is interpreted and analyzed through statistical software SPSS.
Kinetic proteomics identifies targeted changes in liver metabolism and the ribo-interactome by dietary sulfur amino acid restriction
Authors: Jonsson William O. , Borowik Agnieszka K. , Pranay Atul , Kinter Michael T. , Mirek Emily T. , Levy Jordan L. , Snyder Elizabeth M. , Miller Benjamin F. , Anthony Tracy G. 
Published: March 2023

AbstractDietary sulfur amino acid restriction (SAAR) protects against diet-induced obesity, extends healthspan, and coincides with an overall reduction in hepatic protein synthesis. To explore the underpinnings of SAAR-induced slowed growth and its impact on liver metabolism and proteostasis, we resolved changes in hepatic mRNA and protein abundances and compared synthesis rates of individual liver proteins. To achieve this, adult male mice were provided deuterium-labeled drinking water while freely consuming either a regular-fat or high-fat diet that was SAA restricted. Livers from these mice and their respective dietary controls were used to conduct transcriptomic, proteomic, and kinetic proteomic analyses. We found that remodeling of the transcriptome by SAAR was largely agnostic to dietary fat content. Shared signatures included activation of the integrated stress response alongside alterations in metabolic processes impacting lipids, fatty acids, and amino acids. Changes to the proteome correlated poorly with the transcriptome, and yet, functional clustering of kinetic proteomic changes in the liver during SAAR revealed that the management of fatty acids and amino acids were altered to support central metabolism and redox balance. Dietary SAAR also strongly influenced the synthesis rates of ribosomal proteins and ribosome-interacting proteins regardless of dietary fat. Taken together, dietary SAAR alters the transcriptome and proteome in the liver to safely manage increased fatty acid flux and energy use and couples this with targeted changes in the ribo-interactome to support proteostasis and slowed growth.
#Sponseredathlete: the marketing of image and performance enhancing drugs on Facebook and Instagram
Authors: Gibbs Nick 
Published: March 2023

AbstractThis article sets out to investigate the marketing of image and performance enhancing drugs (IPEDs) on the social media platforms Facebook and Instagram. Drawing upon a ‘connective’ ethnographic exploration of IPED use and supply, the paper first outlines a supplier typology on these platforms, before shedding light on the marketing strategies employed by sellers in order to overcome the inherent distrust of online sales and build a trustworthy brand. Techniques identified include athlete sponsorship, the sharing of bodybuilding fitspiration content, self-objectification, posting images showcasing transformation photos and customer feedback, and seasonal sales and promotions. Analysis encompasses the centrality of product branding, the overlaps between licit and illicit market advertising strategies, and the affordances of the platforms under study. Finally, conclusions relating to the implications of these findings to scholarship, policy, and regulation are offered.
Metabolic dysfunction–associated fatty liver disease (MAFLD): an update of the recent advances in pharmacological treatment
Authors: Sangro Paloma , de la Torre Aláez Manuel , Sangro Bruno , D’Avola Delia 
Published: March 2023

AbstractMetabolic dysfunction–associated fatty liver disease (MAFLD) is nowadays considered the liver manifestation of metabolic syndrome. Its prevalence is increasing worldwide in parallel to the epidemic of diabetes and obesity. MAFLD includes a wide spectrum of liver injury including simple steatosis and non-alcoholic steatohepatitis (NASH) that may lead to serious complications such as liver cirrhosis and liver cancer. The complexity of its pathophysiology and the intricate mechanisms underlying disease progression explains the huge variety of molecules targeting diverse biological mechanisms that have been tested in preclinical and clinical settings in the last two decades. Thanks to the large number of clinical trials of the last few years, most of them still ongoing, the pharmacotherapy scenario of MAFLD is rapidly evolving. The three major components of MAFLD, steatosis, inflammation, and fibrosis seem to be safely targeted with different agents at least in a large proportion of patients. Likely, in the next few years more than one drug will be approved for the treatment of MAFLD at different disease stages. The aim of this review is to synthesize the characteristics and the results of the most advanced clinical trials for the treatment of NASH to evaluate the recent advances of pharmacotherapy in this disease.
LDP and CLT for SPDEs with transport noise
Authors: Galeati Lucio , Luo Dejun 
Published: March 2023

AbstractIn this work we consider solutions to stochastic partial differential equations with transport noise, which are known to converge, in a suitable scaling limit, to solution of the corresponding deterministic PDE with an additional viscosity term. Large deviations and Gaussian fluctuations underlying such scaling limit are investigated in two cases of interest: stochastic linear transport equations in dimension$$D\ge 2$$D≥2and 2D Euler equations in vorticity form. In both cases, a central limit theorem with strong convergence and explicit rate is established. The proofs rely on nontrivial tools, like the solvability of transport equations with supercritical coefficients and$$\Gamma $$Γ-convergence arguments.
Effect of targeted intervention on C-terminal agrin fragment and its association with the components of sarcopenia: a scoping review
Authors: Kumar Prabal , Nayak Kusumakshi , Umakanth Shashikiran , Girish N. 
Published: March 2023

AbstractBackgroundC-terminal Agrin Fragment (CAF) has emerged as a potent biomarker for identifying sarcopenia. However, the effect of interventions on CAF concentration and the association of CAF with sarcopenia components are unclear.ObjectiveTo review the association between CAF concentration and muscle mass, muscle strength, and physical performance among individuals with primary and secondary sarcopenia and to synthesize the effect of interventions on the change in the level of CAF concentration.MethodsA systematic literature search was conducted in six electronic databases, and studies were included if they met the selection criteria decided a priori. The data extraction sheet was prepared, validated, and extracted relevant data.ResultsA total of 5,158 records were found, of which 16 were included. Among studies conducted on individuals with primary sarcopenia, muscle mass was significantly associated with CAF levels, followed by hand grip strength (HGS) and physical performance, with more consistent findings in males. While in secondary sarcopenics, the strongest association was found for HGS and CAF levels, followed by physical performance and muscle mass. CAF concentration was reduced in trials that used functional, dual task, and power training, whereas resistance training and physical activity raised CAF levels. Hormonal therapy did not affect serum CAF concentration.Conclusion(s)The association between CAF and sarcopenic assessment parameters varies in primary and secondary sarcopenics. The findings would help practitioners and researchers choose the best training mode/parameters/exercises to reduce CAF levels and, eventually, manage sarcopenia.