bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacts of Clinical and Demographical Aspects on the Duration of Pytiriasis Versicolor
Authors: M Kharis Khamdan  , Yuri Widia, dr., SP.KK  , Dr. Rebekah J. Setiabudi, dr., M.Si  , Evy Ervianti, dr., Sp.KK(K)  
Published: August 2023

Background: Pityriasis versicolor (PV) or tinea versicolor is a superficial fungal infection characterized by macules on the skin. It is generally caused by the fungus Malassezia. PV is found throughout the world, especially in tropical countries. Generally, this infection is influenced by humidity, hyperhidrosis, and population density around the world. One of the ways to establish PV is through the KOH examination. Purpose: Evaluating the correlation between the clinical and demographic factors and the duration of illness of outpatient PV patients of the Mycology Division of Dermatology and Venereology Department at Dr. Soetomo General Academic Hospital from 2018 to 2020. Methods: This is an observational analytic study based on medical records at the outpatient clinic of Mycology Division of the Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital. The data was collected in October 2021. The chi-square test is used to analyze the data in this study. Result: 216 PV patients’ data was collected. Most gender was male, most age group was 20-60, most weight group was 51 – 60 kg, most regional origin was from Surabaya, and most duration of infection was <3 months. In this study, topical and systemic treatment of this disease had a significant relationship with patients’ duration of illness (topical p=0.05; systemic p=0.026). Conclusion: Topical and systemic treatment of this disease has a significant relationship with the duration of illness in PV patients.
The Effects of Hormonal Factor on the Degree of Acne Vulgaris Severity
Authors: Alarik L. Albertus , Indiastuti Danti Nur , Astari Linda , Setyaningrum Trisniartami 
Published: August 2023

Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85% in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.
Covid-19 In A Patient With Pemphigus: A Case Report
Authors: Dwizella Nandya , Pratama Nevristia 
Published: August 2023

Background: Pemphigus disease, especsially Pemphigus Vulgaris (PV), is an autoimmune disease resulting in blisters on the skin and mucosa due to autoantibodies attacking desmogleins (DSG) 1 and 3. Autoimmunity development in PV may be idiopathic or induced by neoplasms, drugs, infections, or inflammatory processes. Besides affecting the respiratory tract, COVID-19 may also affect other systems, such as the skin. The pathogenesis of autoimmune diseases and COVID-19 have similarities, which is an overreaction of the immune system. Purpose: To report a case about the association between PV autoimmune disease and COVID-19. Case: A 30-year-old woman presented with full-body pain and ulcers. Three days before the skin lesions, the patient complained of a mild cough, and the SARS-CoV-2 examination was positive. The patient was treated with systemic and topical corticosteroids along with broad-spectrum antivirals. The patient was discharged with an improved lesion condition and a negative SARS-CoV-2 PCR on day 5 of treatment. Discussion: Prolonged viral infection or viral infection itself, such as COVID-19 can cause immune system dysregulation leading to autoimmune skin lesions with different mechanisms. The use of corticosteroids or immunosuppressants in autoimmune diseases increases the risk of COVID-19 infection in a pandemic. Conclusion: In the COVID-19 pandemic, COVID-19 and autoimmune diseases such as pemphigus vulgaris are interrelated with the presence of immune dysregulation leading to skin lesions
Mesoscopic Deformation of a Hydraulic and Mechanical Aperture of a Single Fracture under Normal Stress
Authors: Ma Haichun , Wang Jingping , Qian Jiazhong , Luo Qiankun 
Published: August 2023

Abstract
Studies have focused on describing the interactions between the fluid flow characteristics and structural deformation of fractures at the mesoscopic scale, which is a scale between the macroscale and the microscale. In this work, a three-dimensional numerical simulation based on the Navier-Stokes equation was carried out to investigate the effect of normal stress on the fracture morphology distribution, the fluid flow characteristics distribution, and the interdependence between the flow and stress in a single mesoscopic fracture. Two fracture surfaces of a mesoscopic rough-walled fracture model were created. Results suggest that the nonlinear relationship between the normal stress and deformation due to the area of the total closure increases unevenly. Distributions of the mechanical aperture are approximated well by a normal distribution. Change in the fluid flow is due to the increase in the fractional contact area. The low-velocity zones are surrounded by relatively smaller apertures, which gradually close and join the areas of total closure. Under the limitation of the total closure areas of the two fracture surfaces, the appearance of channel flow behavior. Compared with the flow in the X- and Y-directions, normal stress-induced flow anisotropy occurred. The mesoscopic quantitative relationship between the strains in terms of the mechanical/hydraulic aperture was determined and proven. A macroscopic relationship between the intrinsic permeability and the strain was deduced, which enhances the evaluation and design of various geological engineering applications in which fracture deformation is considered.
C, O, and Sr Isotope Compositions of Belemnites from the Bajocian–Bathonian of Arctic Siberia: Implications for Global Correlations and Paleogeographic Reconstructions
Authors: Dzyuba O.S. , Shurygin B.N. , Izokh O.P. , Kuznetsov A.B. , Kosenko I.N. 
Published: August 2023

Abstract—The Middle Jurassic sedimentary strata of Siberia remain poorly studied chemostratigraphically. We contribute to the knowledge with pioneering C, O, and Sr isotopic data for carbonate material of belemnites from the Yuryung-Tumus Peninsula and the lower reaches of the Lena River, as a basis for comprehensive description of the north Siberian Bajocian and lower Bathonian. The obtained chemostratigraphic constraints, with new 87Sr/86Sr ratios and previous δ13C and δ18O estimates, also include data for the lower Bathonian in the Sokur section (Central Russia). Despite the limited amount of material, chemostratigraphy, along with the available biostratigraphic data, allows reliable correlation of the Boreal sections with the primary standard of Northwest Europe, which is impossible for these strata with any of the two methods alone. The δ13C, δ18О, and 87Sr/86Sr patterns correlate with the records of eustatic, climatic, tectonic, and paleogeographic events. The new δ18O data and the inferred paleotemperatures for the latest early Bajocian and the Bajocian/Bathonian boundary reveal two excursions of notable seawater warming near the Siberian Arctic coast, which were synchronous with episodes of global sealevel rise. It was presumably during the eustatic events that the N–S Komi Strait (first naming) opened twice in the territory of the Russian Plate. The strait connected the Boreal and Tethyan seas and thus changed the oceanic circulation patterns. Specifically, it opened a gateway for a warm current from the south to northern Siberia responsible for the high seawater temperatures recorded in the δ18О patterns of belemnites.
Integrated Production Modelling to Accelerate Recovery in a Mature Giant Gas Reservoir
Authors: Ameen Nadir , Rehman Saad , Awan Faheem , Nawaz Ahmad , Mumtaz Yasir 
Published: August 2023

Abstract
A quick assessment of the merits of various development strategies can be performed by operating companies whilst having a tool at their disposal consisting of all elements of a production system. To fulfil this requirement, an Integrated Production Model (IPM) of a giant onshore gas field in the Indus Basin of Pakistan was developed. This paper aims to highlight the workflow and lessons learnt in development and calibration of the model. It also showcases the utility of such models. The field in this case study consists of a single giant volumetric reservoir containing dry gas fluid. There are more than one hundred production wells and over 300 km of surface pipeline network. This study had two phases, in the first phase, key elements of the production system i.e. reservoir, wells and surface facilities were modelled and calibrated independently. Reservoir is modelled via multi-tank approach wherein each tank represented a different pressure region of the reservoir. Communication between the tanks was modelled through inter-tank transmissibilities. The surface network was broken down into clusters for ease of development and calibration. After completing calibration of the key elements explicitly; individual elements were brought together to form an integrated production system in GAP and the integrated response of the model is matched against the observed performance which completed the first phase of the study.
During second phase, the history matched IPM Model is then used for evaluating the impact of potential development activities in forecast mode aimed for increase in the delivery pressure, field plateau extension and reserves acceleration & increment. Development activities include infill drilling, tubing optimization, acid-stimulation, surface de-bottlenecking and nodal/wellhead compression. This allowed for ranking of the development activities based on their impact in an integrated mode. Furthermore, the impact of variable delivery pressure and scheduling of different scenarios was also highlighted. The paper also highlights the limitations of the integrated model requiring the use of assumptions in development and calibration phase, particularly with regards to the subsurface model for accurately predicting water rates. The importance of updating the model as part of routine functions is also deliberated.
It was concluded that for making short to medium-term prediction runs and evaluating development strategies, the IPM is an extremely useful tool. It is strongly recommended to develop an IPM early in the field life and plan reservoir management activities & surface network accordingly.
The demonstration of the calibration methodology, workflows and development strategies aided with examples in a unique setting provide a renewed opportunity to develop an understanding on developing and maintaining integrated production models.
The Characterization of Geological Flow Units in Carbonate Reservoirs - Integration of Core, Log & Production Logging Data
Authors: Ali Mehar , Saqib Chaudhary M. , Rizvi Syed M. Iftikhar , Hamim Nasir , Javed Ahsan , Shah Syed M. Usman 
Published: August 2023

Abstract
Geological flow units based on reservoir rock typing can be used to characterize geological facies based on their dynamic behavior. A procedure for identifying and characterizing geological flow units helps resolve some of the key challenges faced in exploration and production of carbonate reservoirs. The current work focuses on the rock typing/flow units classification for reservoir characterization in a carbonate gas reservoir. The Sui Main Limestone (SML) Eocene reservoir, located in the southwestern part of the Middle Indus Basin in Baluchistan Province was selected, and the study carried out using core, wireline logs of 30+ wells and production logging data. The reservoir was previously categorized based on the geological information into four layers.
An integrated workflow was used for characterization of Geological Flow Units based on all available information. The Sui Main Limestone (SML) reservoir was divided into three flow units/rock types, depending on the well log patterns, core data, Porosity–Water saturation relationships, flow zone indicators (FZIs), and the Porosity–Permeability relationships. Production logging data was used to validate flow unit classification.
The field is a gas bearing reservoir composed of medium hard to hard limestone characterized by high porosity but poor/low permeability. The matrix permeabilities and porosity range from 0.01–40 mD and 0–35 percent respectively. Three rock types and groups have been identified in the SML formation; the first group represents the poor reservoir quality (GFU-1) Highly cemented limestone, the second group reflects the moderate reservoir quality (GFU-2) Moderately cemented limestone, and the third group represents the very good reservoir quality (GFU-3) poorly cemented limestone.
Production logging data was used to validate flow unit classification. Pressure Transient Analysis (PTA) indicated that only partial penetration occurred, and therefore only a portion of the perforated area was contributing to production. Specifically, the majority of inflow zones identified in the production logging data corresponded to GFU-3 flow units. As expected, the other two flow units only provide a small increase in production. This further validated the partial penetration model determined from PTA.
Geological flow units/rock types in these thick carbonate reservoirs and can be helpful in selecting optimum perforation intervals rather than perforating the whole thickness. This innovative method can save significant CAPEX without compromising the production.
Base Management Production System Optimization
Authors: Noman M. , Zafar J. , Awase A. 
Published: August 2023

ABSTRACT
Base management provides framework for managing the production base and maximizing recovery through efficient depletion. A vital element of base management practice is system optimization which includes modelling, prioritizing, and implementing strategies to enhance production & reserves of all fields. The process starts with a holistic network model1 that includes integrating reservoir, wellbore hydraulics, gathering system and production facilities. System wide evaluation is conducted using this integrated model and recommendations are networked with cross-functional teams. Finally, these observations are ranked and executed as per business requirements. Given the vast number of active/shut-in wells & fundamentally different field types operated by UEP, this approach is pivotal to effectively manage base production.
This study focuses on key achievements in past few years which delivered fruitful results in terms of production and reserves addition. Below is the summary of activities:
Area-1 comprises of aging fields and the focus has been on creating network flexibility, re-accessing bypassed zones, and compressors modifications to bring the system in the most optimized operating window. Area-2 is primarily gas producing region and opportunities on Well hydraulics, surface compression, system de-bottlenecking, and plant optimization remain in the forefront. Figure-3 demonstrates a case of successfully managed base through multiple optimization activities.
The initiatives discussed in this study significantly contributed to optimizing base production of Area-1 & 2, enabling them to maintain optimum production levels.
Direct Numerical Simulation of Packed and Monolith Syngas Catalytic Combustors for Micro Electrical Mechanical Systems
Authors: Bazooyar Bahamin , Zhu Mingming , Manovic Vasilije , Nabavi Seyed Ali 
Published: August 2023

Abstract
In this work, a catalytic combustor for micro electrical mechanical system for
syngas was designed and analysed using Direct Numerical Simulation (DNS) in conjunction with
finite rate chemistry. The effect of catalyst (platinum (Pt), palladium (Pd), palladium oxide (PdO),
and rhodium (Rh)), bed type (packed with twelve catalyst shapes and four catalyst monolith),
shapes (packed: cylinder, hollow cylinder, four cylinder, single cylinder, single cylinder, crosswebb,
grooved, pall-ring, hexagonal, berl-saddle, cube, intalox-saddle, and sphere, monolith:
triangular, rectangular, hexagonal, and circular), and operating conditions (inlet temperature and
velocity, fuel/air ratio, different concentrations CH4-H2-CO) on combustion efficiency and
pressure drop were studied using different parameters (combustion efficiency (η), pressure drop,
effectiveness factor ( ψ ), and fuel conversions (H2 and CH4 conversions)). Analysis under
different operating conditions reveals that the designed combustor can operate effectively with
syngas of varying compositions with a high combustion efficiency of over 85%. Combustion
mainly takes place on the surface of the catalyst without gas phase reaction with pressure drops
between 18 Pa to 155 Pa. The intalox saddle shape catalysts resulted in the bed effectiveness factor
0.931. The Damköhler for hydroxyl radicals (OH) over the entire length of the reactor is uniformly
distributed and well below 3, suggesting uniform combustion.
Comprehensive Morphometric Analysis of Apple Fruits and Weighted Class Assignation using Machine Learning
Authors: Dujak Christian , Jurado Federico , Aranzana Maria Jose 
Published: August 2023

Abstract
Fruit morphology description for variety registration or evaluation is mostly based on human visual inspection. However, the development of an objective and efficient method for evaluating apple fruit shape would be of significant value. Furthermore, if this method can provide a comprehensive assessment of the multiple attributes encompassed by the term “shape”, it would have great potential for genomic studies. Here, we investigated the potential of a shape analyzer software originally developed to study tomato fruits (Tomato Analyzer) for the morphometric description of apple fruits. We conducted an analysis of 12,920 images of apple sections from 364 genotypes, collected across three harvest seasons. Also, we assigned the images into classes by visual inspection. The software detected the contour of the fruits in most of the images, but with some degree of imprecision, particularly in the stalk and calyx regions. After manual correction of the contours, we obtained 15 measurements of shape and size attributes. In general, size traits had higher heritability (H2) than shape traits (0.72 vs 0.45 in average, respectively). A Random Forest model was used to identify the most important variables determining fruit shape. The fruit shape index external I (FSII) outstood in importance, followed by the fruit shape triangle (FST), the distal angle Macro (DAMa), the eccentricity (ECC), and the proximal angle macro (PAMa). Incorporating these parameters into fruit description guides could provide more precise descriptions of apple cultivars. Additionally, this data will be useful to investigate the potential genetic control of these traits through genomic studies.
The development of NESTED-LAMP method as a novel approach for diagnostic purposes while using Leishmania parasite as the study model
Authors: Yazdanpanah Ava , Samsami Sahar , Ghasemian Abdolmajid , Namavari Sahar , Ataei Saeed , Sepahi Neda , Namavari Negin , Ghanbariasad Ali 
Published: August 2023

Abstract
Loop-mediated isothermal amplification (LAMP) does not require thermal cycler machines to amplify DNA and has the potential to revolutionize molecular biology by bypassing the need for sophisticated equipment. The method also has a low running cost and short turnaround times with higher sensitivity when compared with many other amplification methods. The objective behind this study was to introduce a new platform for LAMP assay with improved sensitivity. In order to do such, Leishmania spp parasites were used as the study model for the investigation purposes. A new primer set (four primers plus two extra ones) were designed and optimized for the novel LAMP assay which we further assigned the name “NESTED-LAMP”. The primers target included ITS1 gene locus of cutaneous leishmaniasis (CL) to enhance the assay sensitivity. The minimum of detection of this new assay was further compared with the traditional LAMP assay, polymerase chain reaction (PCR), and real-time PCR (RT-PCR) methods. NESTED-LAMP detected 1 parasite/µL while the conventional counterpart technique was able to detect 105 parasites/µL. The sensitivity of PCR and RT-PCR declined when the concentration of parasite/µL was below 105 and 102, respectively. Furthermore, this study demonstrated 100% specificity and sensitivity regarding the NESTED-LAMP method. This method could be employed as a suitable alternative for diagnostic purposes as the results demonstrated a 105-fold improvement in sensitivity for the NESTED-LAMP approach compared with the conventional counterpart technique. Also, the cost-efficiency with higher sensitivity and specificity ensures the accuracy of the results.
Does climate variability influence internal migration flows in Senegal? An empirical analysis
Authors: Diallo Alassane 
Published: August 2023

Abstract
This paper aims to estimate the total effect of climate variability on inter-regional migration flows in Senegal. We match regional climate data at origin, represented by normalised rainfall and normalised temperatures (maximum and minimum), with regional migration flow data from Senegal's Agence Nationale de la Statistique et de la Démographie (ANSD) censuses to construct a panel database covering the five-yearly internal migration waves of 1976, 1988, 2001 and 2013. Using a gravity equation model where migration flows are explained by measures of climatic variability at origin, controlled for geographical, socio-economic and demographic factors traditionally identified in the literature. Our results show that only negative precipitation anomalies at the origin area act as a push factor and accelerate emigration. In the predominantly agricultural regions, rainfall deficits appear, alongside traditional socio-economic variables, as an additional significant factor shaping mobility across the country.