bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ASAS-SN bright supernova catalogue – V. 2018–2020
Authors: Neumann K D , Holoien T W-S , Kochanek C S , Stanek K Z , Vallely P J , Shappee B J , Prieto J L , Pessi T , Jayasinghe T , Brimacombe J , Bersier D , Aydi E , Basinger C , Beacom J F , Bose S , Brown J S , Chen P , Clocchiatti A , Desai D D , Dong Subo , Falco E , Holmbo S , Morrell N , Shields J V , Sokolovsky K V , Strader J , Stritzinger M D , Swihart S , Thompson T A , Way Z , Aslan L , Bishop D W , Bock G , Bradshaw J , Cacella P , Castro-Morales N , Conseil E , Cornect R , Cruz I , Farfan R G , Fernandez J M , Gabuya A , Gonzalez-Carballo J-L , Kendurkar M R , Kiyota S , Koff R A , Krannich G , Marples P , Masi G , Monard L A G , Muñoz J A , Nicholls B , Post R S , Pujic Z , Stone G , Tomasella L , Trappett D L , Wiethoff W S 
Published: February 2023

ABSTRACT
We catalogue the 443 bright supernovae (SNe) discovered by the All-Sky Automated Survey for Supernovae (ASAS-SN) in 2018−2020 along with the 519 SNe recovered by ASAS-SN and 516 additional mpeak ≤ 18 mag SNe missed by ASAS-SN. Our statistical analysis focuses primarily on the 984 SNe discovered or recovered in ASAS-SN g-band observations. The complete sample of 2427 ASAS-SN SNe includes earlier V-band samples and unrecovered SNe. For each SN, we identify the host galaxy, its UV to mid-IR photometry, and the SN’s offset from the centre of the host. Updated peak magnitudes, redshifts, spectral classifications, and host galaxy identifications supersede earlier results. With the increase of the limiting magnitude to g ≤ 18 mag, the ASAS-SN sample is nearly complete up to mpeak = 16.7 mag and is 90 per cent complete for mpeak ≤ 17.0 mag. This is an increase from the V-band sample, where it was roughly complete up to mpeak = 16.2 mag and 70 per cent complete for mpeak ≤ 17.0 mag.
Magnetic topologies of two weak-line T Tauri stars TAP 4 and TAP 40
Authors: Xiang Yue , Gu Shenghong , Donati J-F , Hussain G A J , Cameron A Collier , collaboration the MaT Y S S E 
Published: February 2023

ABSTRACT
We present a Zeeman–Doppler imaging study of two weak-line T Tauri stars TAP 4 and TAP 40, based on the high-resolution spectropolarimetric observations with ESPaDOnS at the Canada–France–Hawaii Telescope in November 2013, in the framework of the Magnetic Topologies of Young Stars and Survival of close-in giant Exoplanets large programme. We apply two Zeeman–Doppler imaging codes to the Stokes I and V profiles to reconstruct their brightness and large-scale magnetic field images. The results given by the two imaging codes are in good agreement with each other. TAP 4 shows a large polar cool spot and several intermediate-latitude warm spots on its surface, whereas TAP 40 exhibits very weak variations in its Stokes I profiles, suggesting a mostly unspotted photosphere. We detect Zeeman signatures in the Stokes V profiles of both stars. The reconstructed magnetic maps reveal dominantly toroidal fields, which enclose about 60 per cent of the total magnetic energy for both TAP 4 and TAP 40. Both stars show prominent circular ring features of the azimuthal magnetic field. We derive a solar-like surface differential rotation on TAP 4 from the tomographic modelling. The brightness image of TAP 4 is used to predict the radial velocity (RV) jitters induced by its activity. After filtering out the activity jitter, the rms of its RVs is reduced from 1.7 to 0.2 km s−1, but we do not detect any periodic signals in the filtered RVs of TAP 4, implying that it is unlikely to host a close-in exoplanet more massive than ∼3.5MJup at 0.1 au.
Undisciplined
Authors: Lochhead Judith 
Published: February 2023

AbstractMy response to Stephen Lett initially takes a “glass half full” perspective on the current state of the Society for Music Theory, showing that in the early years of the Society there were substantive activities through what would become the Committee on the Status of Women (CSW) to diversify membership and work against biases. I provide a historical accounting of these activities from 1985 to 1995, documenting the many frictions within the operations of the Society. My response concludes with a “glass half empty” observation that more needs to be done and makes a radical suggestion for a Society for the Study of Music.
Roles and evolution of four LEAFY homologs in floral patterning and leaf development in woodland strawberry
Authors: Zhang Yunming , Kan Lijun , Hu Shaoqiang , Liu Zhongchi , Kang Chunying 
Published: February 2023

Abstract
The plant-specific transcription factor LEAFY (LFY), generally maintained as a single-copy gene in most angiosperm species, plays critical roles in flower development. The woodland strawberry (Fragaria vesca) possesses four LFY homologs in the genome; however, their respective functions and evolution remain unknown. Here, we identified and validated that mutations in one of the four LFY homologs, FveLFYa, cause homeotic conversion of floral organs and reiterative outgrowth of ectopic flowers. In contrast to FveLFYa, FveLFYb/c/d appear dispensable under normal growth conditions, as fvelfyc mutants are indistinguishable from wild type and FveLFYb and FveLFYd are barely expressed. Transgenic analysis and yeast one-hybrid assay showed that FveLFYa and FveLFYb, but not FveLFYc and FveLFYd, are functionally conserved with AtLFY in Arabidopsis (Arabidopsis thaliana). Unexpectedly, LFY-binding site prediction and yeast one-hybrid assay revealed that the transcriptional links between LFY and the APETALA1 (AP1) promoter/the large AGAMOUS (AG) intron are missing in F. vesca, which is due to the loss of LFY-binding sites. The data indicate that mutations in cis-regulatory elements could contribute to LFY evolution. Moreover, we showed that FveLFYa is involved in leaf development, as approximately 30% of mature leaves have smaller or fewer leaflets in fvelfya. Phylogenetic analysis indicated that LFY homologs in Fragaria species may arise from recent duplication events in their common ancestor and are undergoing convergent gene loss. Together, these results provide insight into the role of LFY in flower and leaf development in strawberry and have important implications for the evolution of LFY.
E3 ligase BRG3 persulfidation delays tomato ripening by reducing ubiquitination of the repressor WRKY71
Authors: Sun Chen , Yao Gai-fang , Li Li-xia , Li Ting-ting , Zhao Yu-qi , Hu Kang-di , Zhang Conghe , Zhang Hua 
Published: February 2023

Abstract
Hydrogen sulfide (H2S) is a gaseous signaling molecule reported to play multiple roles in fruit ripening. However, the molecular mechanisms underlying H2S-mediated delay in fruit ripening remain to be established. Here, the gene encoding a WRKY transcription factor, WRKY71, was identified as substantially upregulated in H2S-treated tomato (Solanum lycopersicum) via transcriptome profiling. The expression of WRKY71 was negatively associated with that of CYANOALANINE SYNTHASE1 (CAS1). Transient and stable genetic modification experiments disclosed that WRKY71 acts as a repressor of the tomato ripening process. CAS1 appears to play an opposite role, based on the finding that the ripening process was delayed in the cas1 mutant and accelerated in CAS1-OE tomatoes. Dual-luciferase reporter assay, yeast one-hybrid, electrophoretic mobility shift assay, and transient transformation experiments showed that WRKY71 bound to the CAS1 promoter and suppressed its activation. Moreover, the persulfidation of WRKY71 enhanced its binding ability to the CAS1 promoter. Data from luciferase complementation and Y2H assays confirmed that WRKY71 interacts with a BOI-related E3 ubiquitin-protein ligase 3 (BRG3) and is ubiquitinated in vitro. Further experiments showed that modification of BRG3 via persulfidation at Cys206 and Cys212 led to reduced ubiquitination activity. Our findings support a model whereby BRG3 undergoes persulfidation at Cys206 and Cys212, leading to reduced ubiquitination activity and decreased interactions with the WRKY71 transcript, with a subsequent increase in binding activity of the persulfidated WRKY71 to the CAS1 promoter, resulting in its transcriptional inhibition and thereby delayed ripening of tomatoes. Our collective findings provide insights into a mechanism of H2S-mediated regulation of tomato fruit ripening.
Crisscross multilayering of cell sheets
Authors: Sarkar Trinish , Yashunsky Victor , Brézin Louis , Blanch Mercader Carles , Aryaksama Thibault , Lacroix Mathilde , Risler Thomas , Joanny Jean-François , Silberzan Pascal 
Published: February 2023

AbstractHydrostatic skeletons such as the Hydra's consist of two stacked layers of muscle cells perpendicularly oriented. In vivo, these bilayers first assemble, and then the muscle fibers of both layers develop and organize with this crisscross orientation. In the present work, we identify an alternative mechanism of crisscross bilayering of myoblasts in vitro, which results from the prior local organization of these active cells in the initial monolayer. The myoblast sheet can be described as a contractile active nematic in which, as expected, most of the +1/2 topological defects associated with this nematic order self-propel. However, as a result of the production of extracellular matrix (ECM) by the cells, a subpopulation of these comet-like defects does not show any self-propulsion. Perpendicular bilayering occurs at these stationary defects. Cells located at the head of these defects converge toward their core where they accumulate until they start migrating on top of the tail of the first layer, while the tail cells migrate in the opposite direction under the head. Since the cells keep their initial orientations, the two stacked layers end up perpendicularly oriented. This concerted process leading to a crisscross bilayering is mediated by the secretion of ECM.
High performance w-stacking for imaging radio astronomy data: a parallel and accelerated solution
Authors: Gheller Claudio , Taffoni Giuliano , Goz David 
Published: February 2023

Abstract
Current and upcoming radio-interferometers are expected to produce volumes of data of increasing size that need to be processed in order to generate the corresponding sky brightness distributions through imaging. This represents an outstanding computational challenge, especially when large fields of view and/or high-resolution observations are processed. We have investigated the adoption of modern high performance computing systems specifically addressing the gridding, fast Fourier transform, and w-correction of imaging, combining parallel and accelerated solutions. We have demonstrated that the code we have developed can support data set and images of any size compatible with the available hardware, efficiently scaling up to thousands of cores or hundreds of graphic processing units, keeping the time to solution &lt;1 h even when images of the size of the order of billions or tens of billions of pixels are generated. In addition, portability has been targeted as a primary objective, both in terms of usability on different computing platforms and in terms of performance. The presented results have been obtained on two different state-of-the-art high performance computing architectures.
Interventions Addressing Cannabis Use During Pregnancy: A Systematic Review
Authors: Groff Destin , Bollampally Pooja , Buono Frank , Knehans Amy , Spotts Hannah , Bone Curtis 
Published: February 2023

Objectives
The prevalence of cannabis use among pregnant women is increasing in the United States and places mothers and infants at risk of multiple adverse health outcomes. Given the uncertainty expressed by providers regarding how to approach cannabis use during pregnancy and the growing need for a systematic endeavor to curb use in this population, the aim of this study is to conduct a systematic review of interventions focused on reduction in cannabis use during pregnancy.

Methods
We conducted a systematic search of MEDLINE, PsycINFO, CINAHL, Web of Science, SCOPUS, and Cochrane Library to identify studies of interventions that target individuals that engaged in cannabis use during pregnancy. We included studies if they were randomized controlled trials, controlled studies, feasibility studies, pilot studies, as well as observational studies. The primary diagnostic outcome of interest is reduction in cannabis use.

Results
We identified 9 studies for inclusion with sample sizes ranging from 15 to 658 pregnant people. Interventions involved brief counseling, cognitive behavioral therapy (CBT), motivational interviewing (MI), motivational enhancement therapy + cognitive behavioral therapy (MET-CBT), computer-delivered psychotherapy, and psychoeducation. The interventions that were effective primarily used MI, CBT, and/or MET. There was just 1 study that implemented a home intervention and one that explored computer-based psychotherapy.

Conclusions
The studies uncovered through this systematic review suggest that interventions involving CBT and/or MI demonstrate promise for decreasing cannabis use during pregnancy. There is a tremendous need for high-quality studies focused on this population, and the potential for remote and computer-based interventions should be explored more fully.
Reconsidering Race Adjustment in Prenatal Alpha-Fetoprotein Screening
Authors: Burns Nicholas R. , Kolarova Teodora , Katz Ronit , Ma Kimberly , Delaney Shani 
Published: February 2023

OBJECTIVE:
Black racial designation is the only race for which adjustment is recommended for maternal prenatal serum alpha-fetoprotein (AFP) screening. The objective of this study is to reevaluate the relationship between maternal race and maternal serum AFP values in prenatal analyte screening.

METHODS:
This was a single-center retrospective analysis of patients who underwent prenatal analyte screening between January 2007 and December 2020. Nomograms for raw maternal serum AFP values by gestational age were created and compared between patients identified as “Black” and “non-Black” on the laboratory requisition. Multivariable linear regression models were created to evaluate the relationship among gestational age, maternal weight, and maternal race on maternal serum AFP levels. The new models were compared with the laboratory-derived calculations, which used historically determined race adjustments.

RESULTS:
A total of 43,997 patients underwent analyte screening, and 27,710 patients had complete data for analysis. Of these, 6% were identified as Black. Black patients had laboratory blood draws at a mean gestational age of 123 days, compared with 120 days in non-Black patients (P<.001), and had higher maternal weight (mean 170 vs 161 lbs, P<.001). Nomograms for raw maternal serum AFP values did not differ between Black and non-Black patients (P=.065). When adjusted for gestational age and maternal weight, no difference in maternal serum AFP values was identified between Black and non-Black individuals (P=.81).

CONCLUSION:
No difference in maternal serum AFP values was identified between Black and non-Black pregnant individuals when adjusted by maternal weight and gestational age at blood draw. These findings suggest that routine race-based adjustment of maternal serum AFP screening should be discontinued.
Characteristics and Outcomes of Cancer Patients With Venous Thromboembolic Events After Treatment With Immune Checkpoint Inhibitors
Authors: Dutra Barbara , Garcia-Rodriguez Victor , Garcia Rogelio , Szafron David , Abraham Fiyinfoluwa , Khurana Shruti , Lockhart Jonathan , Amin Rajan , Wang Yinghong , Thomas Anusha 
Published: February 2023

Objective:
This study aimed to describe the clinical characteristics and outcomes of patients with venous thromboembolism (VTE) after Immune checkpoint inhibitors (ICI), focusing on patients with gastrointestinal (GI) immune-related adverse events (irAE).

Methods:
In this retrospective, single-center study, we report the clinical outcomes of adult cancer patients who developed a VTE within 2 years of ICI initiation. Patients were excluded if alternate causes of VTE were present apart from malignancy and cancer therapy. The cohort was classified into those with GI-irAE, non-GI-irAE, and no irAE. A control group with ICI exposure without irAE and VTE was selected for comparative analysis.

Results:
Of all ICI-treated patients, 1891 (17.2%) were diagnosed with VTE. In all, 501 (4.6%) had no etiology for VTE aside from malignancy and cancer therapy. Of these, 137 patients were included and classified as: 44 GI-irAE, 42 non-GI-irAE, and 51 no irAE. Chemotherapy within 6 months of ICI therapy was associated with increased VTE risk. There was no difference in the clinical course between those exposed to chemotherapy versus ICI therapy alone, time from ICI initiation to VTE, and VTE type, recurrence, or related hospitalization. While there was no difference in VTE-related mortality, the GI-irAE group was associated with lower all-cause mortality and superior overall survival.

Conclusion:
Combined ICI and chemotherapy use increased VTE risk. There is a similar disease course of VTE after ICI exposure, regardless of other irAEs. Co-existing GI-irAE with VTE is associated with superior overall survival. Prospective studies are needed to evaluate the relationship between ICI therapy and VTE and irAE impact on VTE outcomes.
Opioid-related Mortality in United States Death Certificate Data: A Quantitative Bias Analysis With Expert Elicitation of Bias Parameters
Authors: Goldsmith Elizabeth S. , Krebs Erin E. , Ramirez Marizen R. , MacLehose Richard F. 
Published: February 2023

Background:
Opioid-related mortality is an important public health problem in the United States. Incidence estimates rely on death certificate data generated by health care providers and medical examiners. Opioid overdoses may be underreported when other causes of death appear plausible. We applied physician-elicited death certificate bias parameters to quantitative bias analyses assessing potential age-related differential misclassification in US opioid-related mortality estimates.

Methods:
We obtained cause-of-death data (US, 2017) from the National Center for Health Statistics and calculated crude opioid-related outpatient death counts by age category (25–54, 55–64, 65+). We elicited beliefs from 10 primary care physicians on sensitivity of opioid-related death classification from death certificates. We summarized elicited sensitivity estimates, calculated plausible specificity values, and applied resulting parameters in a probabilistic bias analysis.

Results:
Physicians estimated wide sensitivity ranges for classification of opioid-related mortality by death certificates, with lower estimated sensitivities among older age groups. Probabilistic bias analyses adjusting for physician-estimated misclassification indicated 3.1 times more (95% uncertainty interval: 1.2–23.5) opioid-related deaths than the observed death count in the 65+ age group. All age groups had substantial increases in bias-adjusted death counts.

Conclusions:
We developed and implemented a feasible method of eliciting physician expert opinion on bias parameters for sensitivity of a medical record-based death indicator and applied findings in quantitative bias analyses adjusting for differential misclassification. Our findings are consistent with the hypothesis that opioid-related mortality rates may be substantially underestimated, particularly among older adults, due to misclassification in cause-of-death data from death certificates.
Validation of the IMPACT-III Questionnaire in French Children With Inflammatory Bowel Disease
Authors: Vanhelst Jérémy , Béghin Laurent , Drumez Elodie , Djeddi-Dine Djamal , Tuck Dominique , Coopman Stéphanie , Gottrand Frédéric , Ley Delphine 
Published: February 2023

Objectives:
This study assessed the reliability and validity of the IMPACT-III questionnaire, a health-related quality of life (HRQoL) instrument, in French children with inflammatory bowel disease (IBD).

Methods:
Eighty-four children and adolescents (45 boys, aged 14.3 ± 2.7 years) were included in a validation study of the IMPACT-III questionnaire. Patients completed 2 questionnaires for measuring HRQoL: the IMPACT-III and the Pediatric Quality of Life Inventory 4.0 Generic Core Scale (PedsQL). Internal consistency was assessed using Cronbach α. Factor analysis was performed on data from the IMPACT-III to help construct domains. Concurrent validity was assessed by calculating Spearman correlation coefficients.

Results:
Cronbach α for the PedsQL total score was good (0.89). The most robust factor solution was a 3-domain structure: (a) Concerns, (b) Body Image and Physical Condition, and (c) Symptoms and Socializing. All domains had good reliability (0.674–0.863). Only 2 items had to be removed. Discriminant validity was demonstrated by significant differences (P < 0.001) in median IMPACT-III scores between inactive and active disease for the total score (83.3 vs 72.0), and for Concerns (P < 0.002) and Symptoms and Socializing (P < 0.001).

Conclusions:
These results suggest that IMPACT-III appears to be a useful instrument for measuring HRQoL in French children with IBD.
Psychosocial well-being and mental adjustment of patients with stage III melanoma in the re-entry phase: a scoping review
Authors: Visser Anna , Post Lenneke , Dekker Joost , Konings Inge R. 
Published: February 2023

Abstract

Background:
The number of patients with stage III melanoma is rising because of increasing incidence and improved survival thanks to newly available adjuvant treatments. Patients may face specific challenges in the re-entry phase, the first 18 months after treatment, because of a high risk of recurrence and the intensity and long-term side effects of adjuvant treatment. The aims of this scoping review included summarizing the current state of evidence concerning patient psychosocial well-being and mental adjustment to the re-entry phase, as well as identifying knowledge gaps.

Methods:
A systematic literature search was conducted in PubMed and CINAHL using the PRISMA-ScR checklist.

Results:
Two qualitative and seven quantitative studies were included. Some studies found no evidence of diminished social and emotional functioning compared with the general population, while others reported emotional distress and impairment in psychological health. Regarding existential health, frequently expressed concerns encompassed fear of recurrence, hopelessness, and uncertainty about the future. Patients typically used behavioral coping, cognitive coping, and meaning-making to manage challenges in the re-entry phase. Only one study considered the effects of adjuvant therapy use on the re-entry phase.

Conclusions:
Limited evidence is available on the psychosocial status of patients with stage III melanoma in the re-entry phase, a phase in which patients face existential concerns. It may be beneficial to provide patients with support regarding existential concerns and meaning-making, for example by developing a practical tool to help set meaningful goals for the re-entry phase. A better understanding of the psychosocial well-being of these patients, the impact of adjuvant therapy, and the relationship between emotional distress, existential concerns, and meaning-making will require further research.