bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Inflow Control Device Bridges the Gap Between Passive and Autonomous Technologies
Authors: Simonds Floyd , Zhao Liang , Montoya Jose 
Published: March 2023

Abstract
Operators in need of improved reservoir drainage, increases in ultimate recovery, and delay of unwanted fluid production are faced with a choice between passive and autonomous inflow control devices (ICD / AICD) to manage these issues most effectively. Production challenges leading to this choice are increasing as water production in particular across the globe continues to rise.
Passive Inflow Control Devices (ICD) have been used with great effect throughout the world. Multiple variants exist using nozzle, tube, or helical designs to balance inflow in long horizontal wells and those with permeability variations. Each type of ICD has various degrees of viscosity insensitivity, with the nozzle-type being seen as relatively viscosity insensitive, which is true when the viscosities of the oil and water are nearly similar. As the viscosities between the two diverge, however, all passive ICD's produce more water than oil at breakthrough for a given pressure.
As ICD's only delay the onset of water and gas breakthrough, however, the industry moved to develop Autonomous ICD's (AICD), which sense the presence of unwanted fluid without any connection to or intervention from the surface. The majority of AICD devices available currently contain moving parts and require close tolerances to deliver their unique benefits. They were initially specifically designed for light oil applications in long horizontal wells to shut off the majority of produced water overall. While this is desirable in low oil viscosity wells it may not be as effective with increases in viscosity due to the need to produce water in order to produce the oil.
The design proposed in this paper uses no moving parts, significantly restricts water production in a wide range of crude viscosities, is easily configured for a variety of downhole conditions, and delivers passive ICD performance with AICD benefits using a simple, reliable, and unique design.
The tool functions to restrict water production progressively as either oil viscosity or water cut increase without ever completely or nearly completely closing to production, which makes it an excellent solution for marginal production wells, younger reservoirs, and wells with lower overall production rates compared to other technologies.
The paper will discuss the theory of the device's functionality to differentiate between fluids present. Laboratory test results will be shown to demonstrate flow performance as well as API 19ICD[1] testing for erosion, plugging resistance, and mud flow initiation testing. In addition, an example comparing an open hole base case to the new device's performance in a sample reservoir will be discussed.
The First Application of a Cloud-Based Well Engineering Solution in the Middle East Region
Authors: Vij Jitesh , Garg Ankit , Kumar Bimal , Sedgwick Paul , Hussein Ahmad Naim 
Published: March 2023

AbstractLow oil prices over the past few years have led oil and gas organizations to embrace digital transformation to improve the efficiency and quality of well design. Nowadays, digital transformation and reducing well construction can have significant impact on determining the financial viability of a discovery. Teamwork and the collaboration of numerous experts in different disciplines are required to achieve a properly engineered well design that can be executed with minimal risks.Present-day well planning uses several increasingly obsolete techniques, including maintaining spreadsheets as risk registers, sharing multiple design iterations between disciplines, drilling, and geological concerns, manually replanning to accommodate changes, and people working in "silos"—often from different offices or from home. Along with this, planning software, when installed on a computer, may be difficult to maintain and update with new software releases. Often an expert in one discipline will not have visibility on the work done by other engineers, impeding collaboration. Many linear processes lead not only to increased well planning time but also to suboptimal well design resulting in higher planning and execution costs (Bello et al. 2014).Today, the oil and gas industry lag in the adoption of digital technologies and most of the ones that exist are not used commercially. Often, the reason is that these solutions address only a very small part of the entire well construction workflow. They are not fully matured, have a poor user interface, and require heavy computing power. Operators, on the other hand, are looking for a full-suite solution and they do not have the resources or expertise to connect various digital solutions existing in the market from different vendors. The need of the hour is an integrated solution that is easy to adopt, provides a collaborative work environment, is cloud-based to leverage computing power (Tanaka et al. 2018), and most importantly supports all the major well design workflows.In this paper, we discuss the first commercial application of a digital cloud-based well-planning solution in the Middle East region, which enabled Crescent Petroleum to become the first operator to adopt the system in UAE.
Unmanned Rotating Equipment for Normally Unattended Installations (nui)
Authors: Bartolini David , Porciani Daniele , Leto Alessandro 
Published: March 2023

Offshore Oil & Gas operators are facing unprecedented challenges due to need to reduce OPEX while at the same time operating in harsh/remote environments with an ever-top attention on Safety and Carbon Footprint reduction.
Technology innovation, especially on digitalization and control, is a game changer that gives customers the opportunity to adopt low manned or totally unmanned solutions while avoiding any compromise on Cybersecurity standards.
Developing unmanned trains for power generation and compression requires the introduction of different solutions: hardware and control system modifications, surveillance systems, digital services for advanced degradation monitoring.
Construction of a Novel Fracturing Fluid with High Viscoelasticity Induced by Mixed Micelles
Authors: Zhang Yang , Xiao Shuyue , Mao Jincheng , Li Ming , Xu Tao , Mao Jinhua , Wang Quanhang , Huang Zigao , Yang Xiaojiang , Lin Chong , Fu Meitao , Huang Zhiyu , Dong Qi , Luan Qiulei , Zhang Guoshuai 
Published: March 2023

Summary
Successful fracturing operations heavily rely on the performance of fracturing fluids (FFs), which mainly include high sand-carrying capacity (SCC) and significant drag reduction (DR). Herein, a functional copolymer, SRP-6, was synthesized by introducing a zwitterionic surfactant, 4-((3-((3-(docos-10-enamido)propyl)dimethylammonio)-2-hydroxypropyl)amino)benzenesulfonate (SVBS), during polymerization, and its structure was characterized by Fourier transform infrared and 1H nuclear magnetic resonance (NMR). SRP-6 shows superior solubility, hydrodynamic volume, and microstructure in salinity water, thanks to the hydrophilicity of multiple functional groups in the copolymer structure, and the SVBS-induced pseudointerpenetrated network as well as the uniform distribution of multiple functional monomers. Furthermore, the SVBS, as a physical crosslinker, imparts the SRP-6/SVBS solution with outstanding rheological performance, SCC, and DR. In addition, the contribution of elasticity and viscosity to SCC was calculated. These results collectively suggest that the SRP-6/SVBS solution could be potentially used as a high-performance FF for the development of tight reservoirs.
Consensus Weighted Gene Co-expression Network Analysis demonstrates aberrations in folding of actin by CCT/TriC chaperonin family in Celiac disease
Authors: Fadaie Mahmood , Khalafiyan Anis , Ghafouri Elham , Ranjbarnejad Tayebeh , Moein Shiva 
Published: March 2023

Abstract
Background: Celiac disease (CeD) is an autoimmune enteropathy triggered by dietary gluten. Almost 90% of CeD patients have HLA-DQ2 or -DQ8 haplotypes. As a high proportion of first-degree relatives (FDRs) of CeD patients have the same haplotype, it is assumed that they are at a higher risk of disease development than the general population. Nevertheless, the prevalence of CeD among FDRs is considerably low (7.5%).
Methods: In order to figure out this discrepancy, a microarray dataset of intestinal mucosal biopsies from CeD, FDR, and control groups was reanalyzed, and gene co-expression network using WGCNA was constructed. The differentially expressed genes in the opposite modules from the consensus analysis were applied for functional enrichment analysis.
Results: WGCNA analysis identified 10 consensus modules in both CeD and FDR groups, including 5 modules with opposite correlation. Among the genes of opposing modules, 159 of them were identified as commonly differentially expressed genes with an adjusted p-value< 0.05 between FDR and CeD groups. Functional enrichment analysis revealed the significant contributions of these genes in host energy metabolism, programmed cell death, antigen cross presentation, and actin folding. In a deep view to the relation of actin folding to celiac disease occurrence, it was found that misfolding of actin and presentation of anti-actin antibodies occur in CeD patients. The current study reports that this pathway is oppositely regulated in FDR group and this might be a trigger for celiac manifestation.
Conclusions: The consensus signaling pathways with opposing expression patterns identified in this study give us a clue about the gene circuits that are dysregulated in celiac patients. Considering the prominent relation of actin folding to disease occurrence and its opposite manner in celiac patients and healthy individuals, it is proposed that targeting CCT/TriC chaperonin family might result in a reduction of misfolded actin and the production of autoantibodies.
Eye tracking technology to improve communication with intubated critical care patients: a randomized study
Authors: SZYMKOWICZ Emilie , BODET-CONTENTIN Laetitia , MARECHAL Yoann , EHRMANN Stephan 
Published: March 2023

Abstract
Purpose: Communication with patients undergoing mechanical ventilation in the intensive care unit represents a challenge. The aims of the study were (1) to describe communication difficulties related to mechanical ventilation as experienced by caregivers and patients, and (2) to compare the use of a conventional low-tech communication board and a high-tech eye tracking technology-based device in order to improve communication effectiveness of mechanically ventilated patients in intensive care.
Methods: This prospective study consisted of a descriptive cross-sectional part describing the communication difficulties in the intensive care unit and an experimental randomized crossover part comparing the use of two technologically opposed augmentative and alternative communication interfaces. A mixed method approach was applied with a quantitative primary method and a qualitative complementary method.
Results: A total of 101 caregivers and 44 patients participated. Regarding the descriptive part, the communication difficulty analysis confirmed that mechanical ventilation constitutes a major problem in patient-caregiver communication. Regarding the quantitative experimental part, the treatment effects on transmitted messages quantity (2 median messages per exchange for the board versus 4 median messages per exchange for the eye tracking, p < 0.0001), success rate (80% for the board versus 100% for the eye tracking, p < 0.05) and patient satisfaction (68% negative satisfaction level for the board versus 100% positive satisfaction level for eye tracking, p < 0.0001) were significant. Regarding the qualitative experimental part, the communication content covered 8 themes for the board compared to 9 themes for the eye tracking and he use difficulties included 4 categories for the board as well as for the eye tracking.
Conclusion: The eye tracking device may improve communication effectiveness of mechanically ventilated patients compared to the conventional communication board, both quantitatively and qualitatively.
Patient-reported outcomes and healthcare resource utilization in systemic lupus erythematosus: Impact of disease activity
Authors: Touma Zahi , Costenbader Karen H. , Hoskin Ben , Atkinson Christian , Bell David , Pike James , Berry Pamela , Karyekar Chetan S. 
Published: March 2023

Abstract
Background Limited real-world data exists on clinical outcomes in systemic lupus erythematosus (SLE) patients by SLE Disease Activity Index 2000 (SLEDAI-2K), hereafter, SLEDAI. We aimed to examine the association between SLEDAI score and clinical, patient-reported and economic outcomes in patients with SLE.
Methods Rheumatologists from the United States of America and Europe provided real-world demographic, clinical, and healthcare resource utilization (HCRU) data for SLE patients. Patients provided self-reported outcome data, capturing their general health status using the EuroQol 5-dimension 3-level questionnaire (EQ-5D-3L), health-related quality of life using the Functional Assessment of Chronic Illness Therapy (FACIT) and work productivity using the Work Productivity and Activity Impairment questionnaire (WPAI). Low disease activity was defined as SLEDAI score ≤4 and ≤7.5mg/day glucocorticoids; patients not meeting these criteria were considered to have “higher” active disease. Data were compared between patients with low and higher disease activity. Logistic regression estimated a propensity score for SLE based on demographic and clinical characteristics. Propensity score matched analyses compared HCRU, patient-reported outcomes, income loss and treatment satisfaction in patients with low disease activity versus higher active disease.
Results Data from 296 physicians reporting on 730 patients (46 low disease activity, 684 higher active disease), and from 377 patients’ self-reported questionnaires (24 low disease activity, 353 higher active disease) were analyzed. Flaring in the previous 12 months was 2.6‑fold more common among patients with higher versus low active disease. EQ 5D‑3L utility index was 0.79 and 0.88 and FACIT-Fatigue scores were 34.78 and 39.79 in low versus higher active disease patients, respectively, indicating better health and less fatigue, among patients with low versus higher active disease. Absenteeism, presenteeism, overall work impairment, and total activity impairment were 47.0-, 2.0-, 2.6- and 1.5-fold greater in patients with higher versus low disease activity. In the previous 12 months there were 28% more healthcare consultations and 3.4‑fold more patients hospitalized in patients with higher versus low disease activity.
Conclusion Compared to SLE patients with higher active disease, patients with low disease activity experienced better health status, lower HCRU, less fatigue, and lower work productivity impairment, with work absenteeism being substantially lower in these patients.
Generational Effect on Nurses’ Work Values, Engagement, and Satisfaction in an Acute Hospital
Authors: Tan Si Hui Evangeline , Chin Guey Fong 
Published: March 2023

Abstract

Background:
The present nursing workforce comprises four generational of nurses working side-by–side. While such generation blend adds invaluable diversity to the workforce, it also brings added complexity. The study aimed to describe and summarise work values and attitudes of four nursing generations, namely Baby boomers, Generation X, Y and Z.
Method:
A cross-sectional questionnaire study was adopted. A total of 778 nurses from an acute hospital in Singapore had completed the online questionnaire. The Work Value and Attitude scale measuring seven constructs (Work Centrality, Non-compliance, Technology Challenge, Work life balance, leadership, Power, and Recognition) was employed for data collection.
Results:
The Cronbach’s alpha was 0.714 for the overall instrument. Statistically significant differences amongst the four generations of nurses emerged in the Work Value and Attitude scale in the construct of non-compliance (p=0.007), technology challenge (p=0.027), work-life balance (p<0.001), and recognition (p<0.001). No statistically significant differences noted for the rest of the constructs.
Discussion and Conclusion:
The findings of this study highlights that differences in work values and attitudes exist amongst nurses of different generations. Generation-X are less likely to challenge the conventional norm and supervisors. Generation Y and Z are the most tech-savvy generations and can adapt quicker to new technology. There is also greater emphasis for work-life balance as the generation gets younger. Generation Y and Z nurses perceived that younger nurses do not get the due respect and recognition form their colleagues. Acknowledging the generational differences in work values and attitude can facilitate nursing management to tailor strategies to improve individual and organisation performance while creating a work environment that enhance intergeneration harmony and teamwork.
Documenting the wild edible plant’s resources used by Pushtoons, Balochis and Brahvis as survival strategy in the arid Province of Balochistan, NW Pakistan
Authors: Kousar Shazia , Khan Nazar , Abbas Zaheer , Harun Nidaa , Ishaq Kamran , Khan Tahir , Bussmann Rainer W. 
Published: March 2023

AbstractThe current paper elaborates the wild edible plants’ (WEPs) diversity, and associated traditional knowledge among three ethnic groups of Balochistan Province, Pakistan. The field trips were carried out in 2018-2020 employing purposive sampling techniques for respondents. We used open ended semi-structured interviews for data collection. A total of 195 interviews reported 140 plant species in 44 families and 105 genera. Family Brassicaceae (10.17%) showed maximum representation along with Asteraceae (10%), and Apiaceae (6.42%). Eight (8) used categories were determined i.e. eaten fresh (47 spp. 33.57%), as vegetable (46 spp., 32.85%), vegetable and salad (15 spp, 10.71%), salad (14 spp, 10%), beverages only (8 spp, 5.71%), and flavor (7 spp, 5%). Leaves (54 spp., 38.57%) were the most used part followed by fruits (44 spp, 31.42%), tubers (13, 9.28%), bulb (11, 7.8% species), whole plant (8, 5.7%), flowers (4, 2.8%), seeds (4, 2.8), shoots (3, 2.14) young stem (2, 1.42). Seventy five (75) species (53.57%) were cited for mutual utilization and the rest 65 (46.42%) were used differently. Pashtuns hold comparatively significant traditional knowledge and exclusively utilize 44 (31.42%) plant species. Similarly, the Pushtoons and Balochis were sharing considerable species i.e. 13 (9.28%). Jaccard index (JI) discovered that 92 plant species were reported for the first time from the province as WEPs for instanceFerula costata, F.oopoda, Ferula assa-foetida, Allium zhobicum, Asphodelus tenuifolius,andMenoicus linifolius etc.Effect of age, gender and was observed in addition to inter-cultural knowledge heterogeneity. Several geo-climatic changes and anthropogenic factors are causing the fragmentation of existing knowledge. The promotion of these WEPs as crops would underpin the food security and socioeconomic development in the region.
Photoexcitation induced magnetic phase transition and spin dynamics in antiferromagnetic MnPS3 monolayer
Authors: Gao Yinlu , Jiang Xue , Qiu Zhiyong , Zhao Jijun 
Published: March 2023

Abstract
Antiferromagnetic (AFM) spin dynamics is the key issue to develop innovative spintronic devices. Herein, we adopt ab initio nonadiabatic molecular dynamics with inclusion of spin-orbit-coupling (SOC) to investigate the photoinduced excitation of spin dynamics in MnPS3 monolayer as an AFM semiconductor. We find that optical doping can trigger MnPS3 from Néel AFM state to stable ferromagnetic (FM) phase with critical density of 1.11×1014 cm− 2 for electron-hole pairs, which is experimentally achievable. This phase transition can be ascribed to the optically induced mid-gap states of S-p orbitals, which lower the electron excitation energy and strengthen the SOC effect between S-p and Mn-d orbitals. For the nonequilibrium nonadiabatic coupling, the excited S-p electrons first decay to the mid-gap states due to p-p electron-phonon coupling and then relax to the spin-down Mn-d orbitals via SOC to recombine with holes. Such dramatic relaxation process not only prolongs the photogenerated carrier lifetime but also maintains the FM order for a long time up to 648 fs, which provides a possible explanation to the unusual optoelectronic performance of AFM MnPS3 monolayer. Excitingly, the reversible switching of magnetic order via optical means gives important clue for information storage and highly efficient photocatalysts by utilizing AFM semiconductors.
Morphological Information Extraction in medical imaging using deep learning interpretability: application case on craniofacial dysmorphism
Authors: MAKAREMI Masrour , MARCY Benoit , KAADOUD Ikram CHRAIBI , SADR Alireza VAFAEI , Mohammad-Djafari Ali , SADOUN Salomé , DE BRONDEAU François , N'KAOUA Bernard 
Published: March 2023

Abstract
Recent advances in the interpretability of convolutional neural networks (CNNs) have allowed applications in imaging as a novel method for visual feature extraction. We used this approach to investigate the impact of changing occlusal forces on craniofacial architecture in class II retrognathism (C2Rm) pathology. Better understanding the points of impact of C2Rm on the entire skull is a major challenge in the diagnosis, treatment, and management of this dysmorphism, but also allows to be part of the debate on changes in the shape of the skull during human evolution. To address these challenges, we introduced a methodology for extracting morphological information with an interpretable CNN (MIE-ICNN) that combines: 1) a pre-processing step to train a deep CNN, 2) an interpretability step using the Score-CAM method to explain the areas of the radiographs used by the model to identify the pathological class, and 3) a calculation step to generate a global activation map, which represents an average activation map of all classifications. The main conclusions of this study are as follows: I) the proposed technique made it possible to find the anatomical areas affected by C2Rm and already identified in the literature (i.e. the cranial base and the vertebrae), to confirm the involvement of a controversial area (the frontal sinus), and to identify a new structure (the parietal bone) as a biomarker. In addition, the study of the involvement of anatomical zones according to the severity of the dysmorphism (by the same methodology), has made it possible to propose hypotheses on the evolution of the forms of the skulls during human evolution (highlighting, in particular, the role of mastication). This new information enriches the anthropological debate around C2Rm and human evolution, and medical knowledge on the etiology of C2Rm. Finally, through this application on craniospinal architecture, the proposed methodological pipeline appears as a new toolbox to extract and visualize complex morphological systems and will certainly allow new advances in the fields of health and medical imaging.