bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress and Quality of Life in Psoriasis
Authors: Kaur Ramandeep , Sharma Sunita , Das Karobi , Narang Tarun 
Published: September 2023

Introduction Psoriasis is a common dermatological disorder characterized by silvery-white, scaly, and erythematous plaques with or without pruritus. It is an immensely stressful condition, hampering the quality of life with significant psychological morbidity. Objective To assess the level of stress and quality of life among the patients with psoriasis. Methods A nonexperimental descriptive study design was used. Sixty participants were enrolled from Dermatology OPD, PGIMER, Chandigarh, by a purposive sampling technique during October to January 2021. An interview schedule, comprising (a) sociodemographic and clinical profile, (b) Perceived Stress Scale (PSS), (c) Patient Health Questionnaire-4 to assess anxiety (PHQ-4), (d) Patient Health Questionnaire-9 to assess depression (PHQ-9), (e) Patient Global Assessment (PtGA) Scale to assess severity of illness (PtGA), and (f) Dermatology Life Quality Index (DLQI), was used for data collection. Data were collected by a telephonic interview as per the interview schedule. At the end of the interview, patients were asked to send the pictures of affected body parts, which were then assessed by the dermatologist using the Investigator’s Global Assessment (IGA) Scale. Data analysis was done with descriptive and inferential statistics using the Statistical Package for Social Sciences (SPSS version 23). Results Most of (86.7%) the participants reported a moderate level of stress (PSS) and 65% described moderate effect on the quality of life. The assessment of the severity of illness on IGA depicted that 36.7% of participants had mild, 28.3% had moderate, and 26.7% had severe psoriasis. Mild to moderate depression (PHQ-9) was screened in about 25% of the participants. A significant correlation was found between stress, quality of life, anxiety, and depression (<0.001). The severity of psoriasis was significantly correlated with quality of life, anxiety, and depression. Conclusion The study results concluded that the presence of a significant level of stress has a considerable effect on the quality of life among the patients with psoriasis. Thus, it is recommended to assess and address the psychological issues along with medical management for the comprehensive management of patients with psoriasis.
Anxiety Related to “Childbearing Process” Among Women
Authors: Thakur Shelza , Rani Kamlesh , Kalia Raman 
Published: September 2023

Introduction Childbirth is a natural, normal physiological phenomenon that introduces new experiences in women’s reproductive life. It has a great physiological, emotional, and social impact on a woman’s health. If a pregnant woman finds it difficult to adapt to the changes, she may suffer from anxiety and depression and it, in turn, affects the physical and mental health of both the mother and child. Assessing and managing anxiety is one of the most important needs during pregnancy. Objective To assess and compare the anxiety related to the childbearing process among primigravida and multigravida mothers. Methodology A descriptive study was conducted among 300 pregnant women visiting antenatal OPD or admitted before delivery in the selected hospital. The data were collected by interviewing pregnant women as per the interview schedule comprised of sociodemographic profiles and an anxiety scale. The obtained data were analyzed by using descriptive and inferential statistics. Results The results showed that 88% of pregnant women had low anxiety, whereas 12% had moderate anxiety. Anxiety was more common among primigravida women. Conclusion The study concluded that majority of the women had low anxiety during the childbearing process.
Stress Level of Parents of Hospitalized Preterm Neonates
Authors: Kaur Rajbeer , Kaur Sukhwinder , Kumar Praveen , Bagga Rashmi 
Published: September 2023

Background: Preterm birth is an unexpected event, which is very stressful for the parents and family members as they are never prepared for this situation. The major stressors of parental stress such as the appearance of the neonate, neonatal intensive care unit (NICU) environment, condition of the neonate, behaviour of care professionals and financial implications are well documented. Objective: To assess the level of stress among the parents of preterm hospitalized neonates admitted in the NICU, Nehru Hospital, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh. Methods: Data were collected by interviewing 17 parents on the fifth day of admission to the NICU, PGIMER, Chandigarh, after taking informed written consent from them. The Parental Stress Scale–NICU (PSS-NICU) and the fathers stress scale were used to assess the stress level of parents of hospitalized preterm neonates. Data were analysed by using SPSS (version 20). Results: The mean age of mothers was 28.24 ± 4.96 and that of the fathers was 30.29 ± 4.25. The total mean mothers’ stress score was 171.76 ± 33.44, and the total mean fathers’ stress score was 125.02 ± 36.16. Conclusion: The study showed that mothers and fathers were very stressful during the period of hospitalization of their preterm neonates.
Post-discharge Nursing Care Needs and Problems of the Patients with Spontaneous Subarachnoid Hemorrhage who Have Undergone Therapeutic Intervention
Authors: Jamwal Manorma , Aggrarwal Ashish , Singla Navneet , Dhandapani Manju 
Published: September 2023

Background Spontaneous subarachnoid hemorrhage (sSAH) is a neurologic emergency characterized by the extravasation of blood into the subarachnoid space. The patients who had therapeutic intervention may face many problems after their discharge from the hospital, which can be a burden both on the patient and the caregiver. To understand the needs completely, it is necessary to comprehend the problems the patients and caregivers face after discharge related to nursing care. This could lead to improvements in functional status and quality of life. Objectives To identify the nursing care needs and problems of the patients with sSAH who have undergone therapeutic intervention follow-up in tertiary care center Chandigarh. Method A qualitative narrative study was conducted on 21 participants (15 patients paired with caregivers and six health care workers) enrolled through the purposive sampling technique. Using an interview guide, patients’ problems and nursing care needs were identified from patients, caregivers, and health care workers (HCWs). Interviews were documented after having informed written consent from participants. Ethical clearance was taken from the institute committee. Results Various problems were reported by the patients, caregivers, and HCWs. The problems and nursing care needs were grouped under various domains: the physical domain includes headache, rigidity, fatigue, difficulty in the activity of daily living, and many more. The psychological domain has anger, altered memory, concentration, and so on. The problems under the social domain were, not interested in socialization, loss/change of job, disturbing role and responsibility, and so on. The spiritual domain includes decreased/increased faith in God, an inability to practice rituals. Poor therapeutic compliance includes lack of compliance to medical treatment and loss of follow-up. The care need includes a lack of caring skills, knowledge deficit among many. Caregivers reported an increase in burden, disturbed family, financial issues, and lack of caring skills. Conclusion The study found various problems and nursing care needs under seven domains, that is, physical, psychological, social, spiritual, poor therapeutic compliance, care needs, and challenges faced by caregivers, which can be considered during the transition phase of patients with sSAH and may guide the health care worker in the provision of holistic care.
Atezolizumab-induced myositis in a patient with small-cell lung cancer
Authors: Sahin Elif , Cabuk Devrim , Tuncer Kuru Fatma , Yazici Ayten 
Published: September 2023

Objective Myositis, an inflammatory disease affecting muscles, is a rare and potentially fatal immune-related adverse event associated with immune checkpoint inhibitors. There are limited data on its clinical features and management. Case presentation Atezolizumab, in combination with etoposide and carboplatin, was initiated in the patient diagnosed with metastatic small-cell lung cancer. After four cycles, maintenance atezolizumab was initiated. At the third visit of the maintenance therapy, the patient reported weakness, edema, and tightness in the muscles that had progressed over the course of a week. Mild solid-food dysphagia was also observed. Neutrophilic leukocytosis with elevated creatine phosphokinase (9234 U/L), erythrocyte sedimentation rate (111 mm/h), and transaminase levels were observed. A diagnosis of myositis was considered based on clinical findings. Atezolizumab was omitted and an oral 0.5 mg/kg/day dose of methylprednisolone was administered. The myositis resolved within 10 days. During the treatment of myositis, the patient underwent prophylactic cranial irradiation. The steroid dose was tapered off within 35 days and then atezolizumab was restarted. Conclusion The literature contains only a few case reports about atezolizumab-induced myositis, highlighting the challenges in defining its clinical features and management. Prompt diagnosis and treatment are crucial to prevent severe complications, such as myocarditis or respiratory muscle paralysis.
Characteristics of cat semi-owners
Authors: Ma Gemma C , McLeod Lynette J , Zito Sarah J 
Published: September 2023

Objectives Unowned ‘stray’ domestic cats threaten wildlife, as well as create a community nuisance and contribute to high rates of euthanasia in animal shelters. These cats can experience poor welfare, contribute to the pet cat population and compromise attempts to control feral cats. However, many unowned domestic cats are cared for by semi-owners who do not consider they own these cats; therefore, semi-owners are a potentially important target population for human behaviour change interventions. The present study aimed to describe the characteristics of cat semi-owners and compare these with the general population of cat owners and non-cat owners to inform future cat management interventions. Methods An online questionnaire open to all residents of New South Wales, Australia was developed and advertised. Respondents were asked ‘do you care for other free-roaming or stray cats (not including the cats you own)?’, whether they owned cats, about characteristics of their home and their agreement with 15 capability, social opportunity and motivation (COM) items relating to cat containment. Results Questionnaire responses were received from 8708 people, including 588 semi-owners (7%). Semi-owners were significantly more likely to be female, live in urban areas, live in lower socioeconomic areas and rent their home. Most semi-owners also owned their own cats and owned more cats than non-semi-owners. Conclusions and relevance Semi-owners of unowned ‘stray’ cats are a valuable potential target audience for human behaviour change interventions. Understanding that these semi-owners often have their own cats, might already be overwhelmed with cat-caring responsibilities and are disproportionately from lower socioeconomic backgrounds should guide intervention design. A nuanced approach is needed that prioritises the wellbeing of cats and semi-owners for semi-owners to ‘buy in’. Any intervention should also recognise that semi-owners often face multiple, complex barriers to neutering or claiming ownership of the cats they care for, especially cost, and trust in the authorities.
Changes in flexor pollicis longus tendon cross-sectional dimensions after A1 pulley release for paediatric trigger thumb
Authors: Ok Cha Hyeong , Shin Young Ho , Kim Ho Yeon , Kim Jae Kwang 
Published: September 2023

In this study, 30 patients with unilateral paediatric trigger thumb were examined with measurements taken within 1 month before surgery, and at 3 months after surgery. We measured the dorsal-palmar (DP) diameter, radioulnar (RU) diameter and cross-sectional area (CSA) of the flexor pollicis longus (FPL) tendon at two sites: just proximal to the A1 pulley and underneath the A1 pulley using ultrasonography. Following surgical A1 pulley release, the DP diameter, RU diameter and CSA of the FPL tendon just proximal to the A1 pulley significantly decreased from 2.6 mm to 2.2 mm, from 5.1 mm to 4.2 mm and from 11 mm2 to 7.8 mm2, respectively. Additionally, the RU diameter and CSA of the FPL tendon at the area beneath the A1 pulley significantly increased from 2.2 mm to 3.2 mm and from 4.3 mm2 to 5.8 mm2, respectively. This finding suggests that the conformation of the FPL tendon of the affected thumb tends to return to that of the contralateral uninvolved thumb after A1 pulley release. Underdevelopment of the inner space around the A1 pulley may contribute to the development of paediatric trigger thumb. Level of evidence: III
The impact of healthcare systems on the clinical diagnosis and disease-modifying treatment usage in relapse-onset multiple sclerosis: a real-world perspective in five registries across Europe
Authors: Nicholas Richard , Rodgers Jeff , Witts James , Lerede Annalaura , Friede Tim , Hillert Jan , Forsberg Lars , Glaser Anna , Manouchehrinia Ali , Ramanujam Ryan , Spelman Tim , Klyve Pernilla , Drahota Jiri , Horakova Dana , Joensen Hanna , Pontieri Luigi , Magyari Melinda , Ellenberger David , Stahmann Alexander , Butzkueven Helmut , Van Der Walt Anneke , Bezlyak Vladimir , Lines Carol , Middleton Rod 
Published: September 2023

Introduction: Prescribing guidance for disease-modifying treatment (DMT) in multiple sclerosis (MS) is centred on a clinical diagnosis of relapsing–remitting MS (RRMS). DMT prescription guidelines and monitoring vary across countries. Standardising the approach to diagnosis of disease course, for example, assigning RRMS or secondary progressive MS (SPMS) diagnoses, allows examination of the impact of health system characteristics on the stated clinical diagnosis and treatment access. Methods: We analysed registry data from six cohorts in five countries (Czech Republic, Denmark, Germany, Sweden and United Kingdom) on patients with an initial diagnosis of RRMS. We standardised our approach utilising a pre-existing algorithm (DecisionTree, DT) to determine patient diagnoses of RRMS or secondary progressive MS (SPMS). We identified five global drivers of DMT prescribing: Provision, Availability, Funding, Monitoring and Audit, data were analysed against these concepts using meta-analysis and univariate meta-regression. Results: In 64,235 patients, we found variations in DMT use between countries, with higher usage in RRMS and lower usage in SPMS, with correspondingly lower usage in the UK compared to other registers. Factors such as female gender ( p = 0.041), increasing disability via Expanded Disability Status Scale (EDSS) score ( p = 0.004), and the presence of monitoring ( p = 0.029) in SPMS influenced the likelihood of receiving DMTs. Standardising the diagnosis revealed differences in reclassification rates from clinical RRMS to DT-SPMS, with Sweden having the lowest rate Sweden (Sweden 0.009, range: Denmark 0.103 – UK portal 0.311). Those with higher EDSS at index ( p < 0.03) and female gender ( p < 0.049) were more likely to be reclassified from RRMS to DT-SPMS. The study also explored the impact of diagnosis on DMT usage in clinical SPMS, finding that the prescribing environment and auditing practices affected access to treatment. Discussion: This highlights the importance of a healthcare system’s approach to verifying the clinical label of MS course in facilitating appropriate prescribing, with some flexibility allowed in uncertain cases to ensure continued access to treatment.
Psychometric evaluation of the Chinese version of the media Health Literacy Questionnaire: A validation study
Authors: Li Wenbo , Zhang Yanli , Liang Jiaqing , Yu Hongyu 
Published: September 2023

Background The media play an important role in health promotion and disease prevention, while at the same time, a variety of mixed health messages in the media are beginning to pose new challenges to them. However, there is a lack of media health literacy (MHL) assessment tools in China. Therefore, the purpose of this study was to translate the Media Health Literacy (MeHLit) questionnaire into Chinese and to assess its psychometric properties. Methods This cross-sectional study was conducted from October to December 2022, and a methodological study of the translation and validation of the MeHLit questionnaire was conducted. Results As a result of an extensive translation and cultural adaptation process, the final MeHLit questionnaire was developed, which includes five dimensions and 21 items. Cronbach's α value of the questionnaire was 0.859, and Cronbach's α value of the dimensions ranged from 0.776 to 0.911, which is fairly good. As a result, the test–retest reliability coefficient and the split-half reliability coefficient of the questionnaire are both equal to 0.907. Its content validity index was 0.946, suggesting a reasonable level of content validity. Through exploratory factor analysis, a five-factor structure was identified based on the eigenvalues, total variance explained, and scree plot. As a result of the validation factor analysis, all recommended fit indicators were appropriate. Conclusion The Chinese version of the MeHLit questionnaire has been successfully introduced in China. It has shown good psychometric properties among the Chinese public and can be used as a tool to evaluate MHL in health screening.
Bifactor SEM and MIRT Structure of a 12-Item Human Immunodeficiency Virus Stigma Scale in Peruvian Adults
Authors: Ramos-Vera Cristian , Basauri-Delgado Miguel , Diaz Peña Misael , Tinoco Alberto Jose , Perez Arroyo Karen , Herrera Mamani Betsabel , Sánchez-Villena Andy , Saintila Jacksaint 
Published: September 2023

Background: The stigma associated with human immunodeficiency virus (HIV) can lead to prejudice and discrimination against people who have been infected by this virus, consequently, it is important to have a validated tool to measure this phenomenon. However, there is only 1 national precedent that has validated the scores of this instrument in its 21-item version. Therefore, this study examined the bifactor structural equation method (SEM) and multidimensional item response theory (MIRT) structure of a 12-item human immunodeficiency virus stigma scale in Peruvian adults. Methods: We evaluated 342 patients (57.6% female and 42.45% male) diagnosed with HIV receiving highly active antiretroviral therapy (HAART) from a hospital located in East Lima, aged 18 to 45 years ( M = 31.4, SD = 9.79). A SEM was used to test 2 measurement models, a 4-factor correlated oblique model and a bifactor model due to high interfactor relationships. Results: Acceptable fit indices were identified for the oblique model (χ2/df = 1.26, SRMR = 0.044, RMSEA [90% CI] = 0.028 [0.000-0.047], CFI = 0.996, TLI = 0.994). In the same way, similar results were evident for the bifactor model (χ2/df = 1.14, SRMR = 0.039, RMSEA [90% CI] = 0.020 [0.000-0.044], CFI = 0.998, TLI = 0.997), however, in the latter it showed a greater explanation for the unidimensional model ( H = 0.87, PUC = 0.82, LCA = 0.70), which was also evidenced by the bifactor MIRT analysis. Conclusion: It is concluded that the 12-item HIV Stigma Scale meets the psychometric properties of internal structure and unifactorial reliability.
The surgical outcome of postoperative radial neck nonunion: Retrospective case series with systematic review
Authors: Kholinne Erica , Lee Hyun-Joo , Jeon In-Ho 
Published: September 2023

Purposes This study aim to describe surgical outcome in treating postoperative radial neck nonunion and to perform a systematic review to evaluate the surgical outcome of symptomatic radial neck nonunion. Methods The study included ten patients with symptomatic postoperative radial neck nonunion from 2010 to 2016 which were treated surgically with either bone grafting (bone-grafting group) or radial head resection (resection group). The patient demographics, pre- and postoperative clinical scores were recorded. The PubMed, OVID/Medline, Cochrane, Google Scholar, and EMBASE databases were searched using the keywords “radial neck nonunion” according to the MeSH index. A systematic review was performed using PRISMA guidelines. Results Average time from primary surgery to nonunion was 10.7 months. Four and six patients received bone-grafting and radial head resection procedure. The mean age for resection group is older than bone grafting group (59 versus 28.75 years). The resection group patients presented with more significant pre-operative symptoms, associated injuries, loss of radial head articular congruity, and bone loss. All patients achieved favorable outcome. The systematic review included 12 publications with a total of 19 patients. The incidence of radial neck nonunion was 73.7% and 26.3% following conservative and operative treatment respectively. About 42.1% received operative treatment due to symptomatic progression. Conclusions Radial neck nonunion is rare and mostly appears asymptomatic. Operative treatment is advocated for symptomatic cases. Articular congruity and degree of bone loss are major determinant for surgical treatment of radial neck nonunion. Surgical treatment for symptomatic radial neck nonunion resulted in favorable outcome.
ACL Reconstruction With Quadriceps Soft Tissue Autograft Versus Bone-Patellar Tendon-Bone Autograft in Cutting and Pivoting Athletes: Outcomes at Minimum 2-Year Follow-up
Authors: Renfree Sean P. , Brinkman Joseph C. , Tummala Sailesh V. , Economopoulos Kostas J. 
Published: September 2023

Background: The optimal graft choice for anterior cruciate ligament (ACL) reconstruction (ACLR) in the high-level cutting and pivoting athlete remains controversial. Studies have shown similar outcomes when directly comparing bone-patellar tendon-bone (BPTB) autograft versus quadriceps soft tissue (QST) autograft in the general population. However, no studies have directly compared these 2 grafts in athletes participating in cutting and pivoting sports. Hypothesis: It was hypothesized that, compared with BPTB autograft, the QST autograft would result in similar patient-reported outcomes and rates of retear, return to sport, and complications. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective review was performed on athletes participating in cutting and pivoting sports (soccer, American football, lacrosse, and basketball) who underwent primary ACLR with either BPTB autograft or QST autograft chosen by the athlete between January 2015 and January 2019. The International Knee Documentation Committee (IKDC) subjective knee evaluation and Lysholm Knee Scoring Scale were used to evaluate patient-reported outcomes. Return-to-sport and complication rates were identified. Descriptive statistics were expressed using Mann-Whitney test or Student t test for continuous variables and the chi-square test for categorical variables. Results: A total of 68 athletes (32 QST, 36 BPTB) were included for analysis. The percentage follow-up was 89% (32/36) for the QST autograft group and 86% (36/42) for the BPTB autograft group. The 2-year IKDC score (QST, 90.5 ± 6.6 vs BPTB, 89.7 ± 7.8) and 2-year Lysholm score (QST, 91.3 ± 7.5 vs BPTB, 90.5 ± 8.6) were similar between groups. The percentage of athletes able to return to sport within the follow-up period was also similar (88% vs 83%; P = .63). There were 2 retears requiring revision in the BPTB group (6%) and no retears in the QST group ( P = .18). One contralateral ACL rupture occurred in the QST group (3%) and 4 in the BPTB group (11%) ( P = .21). Conclusion: The QST and BPTB autografts demonstrated similar patient-reported outcomes, return-to-sport rates, and complication rates after primary ACLR at 2-year follow-up. Both autografts appear to be reliable and consistent options for ACLR in the cutting and pivoting athlete.