bluuebunny/crossref_metadata_2025_split huggingface dataset:
Instructional Leadership Expenditures at Texas Schools: A Multiyear, Statewide Analysis
Authors: Merik Tania M. , Slate John R. 
Published: March 2023

This study was conducted to determine the degree to which differences were present in the distribution of Instructional Leadership dollars spent per student at the elementary, middle, and high school levels for the 2009-2010 through the 2018-2019 school years in Texas. Texas statewide data for all public schools were obtained from the Texas Education Agency. Because archival data were analyzed, a causal-comparative research design was present. To determine whether statistically significant differences were present in Instructional Leadership dollars spent by school level, inferential statistical procedures were calculated for each school year. Statistically significant differences were established for each school year. The amount of Instructional Leadership dollars spent per pupil were highest at the high school level, followed by the middle school level, and were lowest at the elementary school level. From the 2009-2010 school year through the 2018-2019 school year, expenditures for elementary, middle, and high schools across the State of Texas increased by only $42, $40, and $48, respectively. As such, the Instructional Leadership funding did not keep up with the rate of inflation in this time period.Implications and recommendations for future research were discussed.
Between Tunnel Vision and a Sliding Scale: Power, Normativity and Justice in the Praxis of the International Criminal Court
Authors: Okafor Obiora C. , Ngwaba Uchechukwu 
Published: March 2023

<p>This article examines the relatively extensive, liberal and increasing deployment of the International Criminal Court (ICC) as the central mechanism for redressing gross human rights abuses in Africa. It shines the spotlight on how global and domestic power matrices affect the character and behaviour of international criminal justice norms and institutions, including our sense of what the model approach to international criminal justice ought to be in Africa and elsewhere. Three inter-related arguments are advanced as follows: first, the deployment of the ICC to help redress gross human rights abuses on the African continent has its pros and cons, but its deployment to play a central role as it currently does is fraught with suspicion as regards the true intention; second, when it comes to redressing the gross human rights abuses that are committed on the African continent, as elsewhere, the ICC is not the only viable and available option – there are a range of other reasonable options in the repertoire of international criminal law and policy; and third, it is largely because of the interplay of domestic and global power matrices (and not in the main because of some immanent sense of morality or logic) that international criminal justice has increasingly tended to take one particular, generally inflexible, ICC-heavy, form in its encounters with gross human rights abuses in Africa.</p>
<p> </p>
الألقاء ( في الفضائيات العربية) نظاما اشاريا
Authors: رضا مبارك محمد 
Published: March 2023

أظهر العصر تطورا مهما في الاتصال , مفاهيم واجراءات وتقنية , وأظهر وبالدرجة نفسها عناية باللغة , وما يجمع بين الاعلام واللغة ان احدهما صنو الاخر ورافد له , فالاعلام يستمد وجوده وتحققه من اللغة ومن الانظمة العلاماتية الاخرى , وتتوطد علاقة اللغة بالاعلام بتجذر نظام اللغة الرمزي . إذ يفتح الاعلام لها حقولا معرفية ودلالية , فالتغير الذي وسم الزمن بميسمه , لابد ان يترك اثرا بينا في مفاصل الاعلام الحيوية , والالقاء الاذاعي والتلفزيوني واحد من هذه المفاصل , وقد تغير هو الاخر في اطار حركة النمو والتطور , وتعدد الوسائل والوسائط الاعلامية وانتشارها . وشمل التغير المتلقي قارئا وسامعا ومشاهدا , فما عاد الالقاء قراءة في فقرات مكتوبة , تراعى فيه الفواصل والفقرات والسكنات . ولم يعد تمثلا للمعنى في محاولة تجسيده وتجليته , بل هو فضلا عن ذلك صورة اخرى ترسم بالكلمات وبالاداء , والمعرفة الدقيقة بخصائص اللغة . ولاسيما خصائصها الشفوية , وتظهر الميزات الشخصية والصوتية للمحافظة على النظم الاشارية : نظام الكلمة , نظام الجملة , نظام النص , نظام الخطاب .
وقد حفزعلم اللغة الحديث القائمين بالاتصال على الافادة من المنجز الهائل الذي حققه العصر , منذ بديات القرن العشرين , ولاسيما التقدم في السيميائيات , الذي غدا هو الاخر علامة من علامات عصرنا : ((في فما يسعى (علم الالسنية) الى اختزال الوحدات الدالة الصغرى المميزة انطلاقا من الجملة . تحتل الدراسات السيميائية مكانتها على صعيد أرفع , مستهدفة استقراء النظام الدلالي وفقا لوحدة اكبر من الجملة وهي الخطاب , الذي لايستنتج منه فائدة , بمجرد ضم الوحدات الدلالية الصغرى المكونة له , انما يتم استخلاصه جملة وفي كليته كوحدة كبرى , تتألف من كلية الانساق المختلفة , ولعل الاهتمام الخاص والمتزايد بالسيميائية (التي تأسست ردا على الالسنية) هو نتيجة حاجة مختلف فروع المعرفة لادوات اجرائية قادرة على الوصف والتفسير والتحليل بدرجة عالية من الدقة , اذ نراها تصلح حاليا لان تكون وسيلة فعالة لاستقصاء انماط متنوعة من عمليات الاتصال والتبليغ))1
يعنى الالقاء الاذاعي والتلفزيوني بالانظمة القولية , بدء بنظام الكلمة وأنتهاء بنظام الخطاب , إذ ان الميزة الصوتية والدلالية والصرفية للكلمة , تأتي في اطار اوسع , اي في نطاق نسقين من الانسقة اللغوية والمعرفية هما نسق الجملة ونسق الخطاب . وهذا ما نسعى الي تبيينه في هذا البحث.
MANAGING MEDIA CAMPAIGNS
Authors: Jaeed Hameed 
Published: March 2023

The most famous phenomena in the media administration, is the transfer of power, from the decision-makers inside the administration, especially those who occupy administrative positions by law, to those who enjoy a natural influence based on knowledge, skill and competence, especially on the psychological, political and social sides.
The old way of dividing the administration into heads and hands is no longer accepted, and the separation of thinking and work based on a traditional format has become rather refused.
Also, a chapter like this one might become a constant routine, but it doesn’t keep pace with the development of field concepts and practices of administrations. The logic of modern administration emphasizes the need to reconsider the responsibility of the decision-makers, and mastering new techniques, while respecting the conditions and forms of organizational structures, as well as coming up with new ideas from the practice of administering.
Amylo-AFFECT-QOL, a self-reported questionnaire to assess health-related quality of life and to determine the prognosis in cardiac amyloidosis
Authors: Kharoubi Mounira , Bézard Mélanie , Broussier Amaury , Galat Arnault , Gounot Romain , Poullot Elsa , Molinier-Frenkel Valérie , Fanen Pascale , Funalot Benoit , Itti Emmanuel , Lemonnier François , Sing Chadha Gagan Deep , Guendouz Soulef , Mallet Sophie , Zaroui Amira , Audard Vincent , Audureau Etienne , Le Corvoisier Philippe , Hittinger Luc , Planté Bordeneuve Violaine , Lefaucheur Jean-Pascal , Amiot Aurélien , Bequignon Emilie , Bartier Sophie , Leroy Vincent , Teiger Emmanuel , Oghina Silvia , Damy Thibaud 
Published: March 2023

Background and aimsSelf-reported questionnaires are useful for estimating the health-related quality of life (HR-QoL), impact of interventions, and prognosis. To our knowledge, no HR-QoL questionnaire has been developed for cardiac amyloidosis (CA). This study aimed to validate Amylo-AFFECT-QOL questionnaire to assess HR-QoL and its prognostic value in CA.MethodsA self-reported questionnaire, “Amylo-AFFECT” had been designed and validated for CA symptoms evaluation and screening by physicians. It was adapted here to assess HR-QoL (Amylo-AFFECT-QOL) and its prognostic value in CA. To validate the theoretical model, internal consistency and convergent validity were assessed, particularly correlations between Amylo-AFFECT-QOL and the HR-QoL Minnesota Living Heart Failure (MLHF) questionnaire.ResultsAmylo-AFFECT-QOL was completed by 515 patients, 425 of whom (82.5%) had CA. Wild-type and hereditary transthyretin amyloidosis (ATTRwt and ATTRv) and immunoglobulin light-chain amyloidosis (AL) were diagnosed in 47.8, 14.7, and 18.8% of cases, respectively. The best HR-QoL evaluation was obtained with five dimensions: “Heart failure,” “Vascular dysautonomia,” “Neuropathy,” “Ear, gastrointestinal, and urinary dysautonomia,” and “Skin or mucosal involvement.” The global Amylo-AFFECT-QOL and MLHF scores showed significant positive correlations (rs = 0.72, p &lt; 0.05). Patients with a final diagnosis of CA had a global Amylo-AFFECT-QOL score significantly higher than the control group composed by patients with other diagnoses (22.2 ± 13.6 vs. 16.2 ± 13.8, respectively, p-value &lt; 0.01). According to the Amylo-AFFECT-QOL global results, ATTRv patients’ QoL was more affected than AL patients’ QoL or ATTRwt patients’ QoL. Patients with a higher HR-QoL score had a greater risk of death or heart transplant after 1 year of follow-up (log-rank &lt; 0.01).ConclusionAmylo-AFFECT-QOL demonstrates good psychometric properties and is useful for quantifying HR-QoL and estimating CA prognosis. Its use may help to improve overall management of patients with CA.
Early cretaceous bimodal volcanic rocks in Wuga Co area, central tibet: The first identification of direct products derived from slab sinking in the Bangong-Nujiang suture zone
Authors: Chen Wei , Liu Zhibo , Wang Nan , Wang Genhou , Zheng Ming , Han Ning , Hu Yiling , Yan Xukun 
Published: March 2023

Introduction: The Bangong-Nujiang Suture Zone (BNSZ) in central Tibet is a remnant of the Bangong-Nujiang Ocean that records its entire Wilson Cycle. The model of divergent double-sided subduction (DDS) is crucial for elucidating the evolution of tectonomagmatic activity on both sides of the BNSZ and for understanding why no high-pressure metamorphic rocks occur in the BNSZ. However, the DDS geodynamics remain poorly constrained. In particular, there is a lack of reports on magmatic rocks directly associated with slab sinking in the DDS terminal stage.Methods: This study presents new geochronological, geochemical, and isotopic data for the Early Cretaceous bimodal volcanic rocks around the Wuga Co area.Results: The bimodal volcanic rocks are divided into the Wuga Co rhyolites (SiO2 = 77.0–79.0 wt%) and the Wuga Co basaltic andesites (SiO2 = 53.9–55.5 wt%). The isotopic values of the Wuga Co basaltic andesites with low (87Sr/86Sr)i values (+0.7040 to +0.7044) and high εNd(t) values (+3.8 to +4.1) lie among three endmembers (the BNO sediments in accretionary wedge, depleted mantle and the BNO slab).Discussion: These values indicate the partial melting of a mantle peridotite that interacted with the subducted slab and sediment in the accretionary wedge, which was caused by the sinking of the Bangong-Nujiang oceanic slab. The Wuga Co rhyolites (108 Ma) have low (87Sr/86Sr)i values (+0.703 to +0.706), high εNd(t) values (+2.25 to +2.49), and high εHf(t) values (+5.6 to +10.0). These values indicate that the rhyolite formed by partial melting of juvenile basaltic crust. This study also collected Hf isotope data from both sides of the BNSZ to constrain its evolution. Our results show that the εHf(t) values of magma on both sides of the BNSZ were elevated simultaneously at 130 Ma, which may be caused by the Bangong-Nujiang oceanic slab rupture. Based on these new data, we propose that the Bangong-Nujiang oceanic slab ruptured from the two overlying terranes at approximately 130 Ma and subsequently sank into the mantle at approximately 108 Ma.
Research on borehole repair model and working parameters optimization of self-propelled rotary excavator
Authors: Wang Mian , Guo Pengyu , Dong Wenxin , Yang Fan 
Published: March 2023

The collapse or plugging of gas extraction borehole can result in partial or complete failure of the extraction function, affecting the efficiency of gas extraction and increasing project costs. The integrated friction coefficient k indicates the resistance of the borehole repair system per unit length. The current repairing methods are mainly self-propelled and rotary drilling technology, which ignores the influence of drilling angle and return water flow on integrated friction coefficient k. In this paper, wellbore repair model based on Newton’s variable mass law is established. The relationship between repair length and hydraulic parameters, wellbore parameters and pipeline parameters is derived. The system resistance test experiment is carried out to clarify the influence of well length, angle, backwater and movement speed on the integrated friction coefficient k. Main conclusions are as follows: the integral friction coefficient k is the key parameter of the repair model, the system resistance increases linearly with the increase of drilling repair distance. Backwater exerts backward thrust on the front end of the drill bit and the high-pressure hose, resulting in an increase in the integrated friction coefficient k, the increase of drilling angle and jet pressure can lead to the increase of backwater flow and the increase of integral friction coefficient k. The improved repair model can more accurately predict the maximum repair distance of self-propelled and rotary drill bits. At the repair distance of 104.7 m, the error between the repair value and the experimental value is 5.7 m, which verifies the feasibility of the application of drilling repair in self-propelled and rotary drilling technology.
Investigation of risk factors associated with impaired glucose regulation: Using the momentum equation to assess the impact of risk factors on community residents
Authors: Guo Mengqian , Wang Zhen , Wang Shumei , Wang Jinju , Jiang Qiang 
Published: March 2023

ObjectiveTo identify risk factors for impaired glucose regulation (IGR) and assess their impact on community residents, this study used a questionnaire to conduct cross-sectional surveys and analysis.MethodsOverall, 774 residents of an urban community in northern China (Jian city) participated in this study. Trained investigators conducted surveys using questionnaires. Based on their medical history, respondents were divided into three glucose status groups as follows: normal (NGT), IGR, and diabetes mellitus (DM). Statistical analysis of survey data was performed using SPSS v. 22.0.ResultsAge, hypertension, family history of diabetes (FHD), dyslipidemia, obesity, and cardiovascular and cerebral disease (CVD) were positively correlated with IGR in men and women. IGR was negatively correlated with a sedentary lifestyle in men and positively correlated with being overweight in women. The number of type 2 diabetes mellitus (T2D) risk factors per subject was positively correlated with age in the NGT group. Glucose status deteriorated with increasing age and the number of risk factors. FHD was the strongest risk factor in both men and women.ConclusionsPrevention of IGR includes weight control, physical activity, and prevention of hypertension and dyslipidemia, especially in subjects with FHD.
Emerging of a new CD3+CD31HCD184+ tang cell phenothype in Sjögren’s syndrome induced by microencapsulated human umbilical cord matrix-derived multipotent stromal cells
Authors: Montanucci Pia , Bistoni Onelia , Antonucci Matteo , Pescara Teresa , Greco Alessia , Basta Giuseppe , Bartoloni Elena , Gerli Roberto , Calafiore Riccardo 
Published: March 2023

BackgroundSjögren’s syndrome (SS) is an autoimmune disease hallmarked by infiltration and destruction of exocrine glands. Currently, there is no therapy that warrants full recovery of the affected tissues. Umbilical cord-derived multipotent stromal cells, microincapsulated in an endotoxin-free alginate gel (CpS-hUCMS), were shown to modulate the inflammatory activity of PBMCs in SS patients in vitro, through release of soluble factors (TGFβ1, IDO1, IL6, PGE2, VEGF). These observations led us to set up the present study, aimed at defining the in vitro effects of CpS-hUCMS on pro- and anti-inflammatory lymphocyte subsets involved in the pathogenesis of SS.Methods and resultsPeripheral blood mononuclear cells (PBMCs) upon collection from SS patients and matched healthy donors, were placed in co-culture with CpS-hUCMS for five days. Cellular proliferation and T- (Tang, Treg) and B- (Breg, CD19+) lymphocyte subsets were studied by flow cytometry, while Multiplex, Real-Time PCR, and Western Blotting techniques were employed for the analysis of transcriptome and secretome. IFNγ pre-treated hUCMS were assessed with a viability assay and Western Blotting analysis before co-culture. After five days co-culture, CpS-hUCMS induced multiple effects on PBMCs, with special regard to decrease of lymphocyte proliferation, increase of regulatory B cells and induction of an angiogenic T cell population with high expression of the surface marker CD31, that had never been described before in the literature.ConclusionWe preliminarily showed that CpS-hUCMS can influence multiple pro- and anti-inflammatory pathways that are deranged in SS. In particular, Breg raised and a new Tang phenothype CD3+CD31HCD184+ emerged. These results may considerably expand our knowledge on multipotent stromal cell properties and may open new therapeutic avenues for the management of this disease, by designing ad hoc clinical studies.
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies
Authors: Sabetta Eleonora , Noviello Maddalena , Sciorati Clara , Viganò Marco , De Lorenzo Rebecca , Beretta Valeria , Valtolina Veronica , Di Resta Chiara , Banfi Giuseppe , Ferrari Davide , Locatelli Massimo , Ciceri Fabio , Bonini Chiara , Rovere-Querini Patrizia , Tomaiuolo Rossella 
Published: March 2023

IntroductionSARS-CoV-2 mRNA vaccinations elicit both virus-specific humoral and T-cell responses, but a complex interplay of different influencing factors, such as natural immunity, gender, and age, guarantees host protection. The present study aims to assess the immune dynamics of humoral, T-cell response, and influencing factors to stratify individual immunization status up to 10 months after Comirnaty-vaccine administration.MethodsTo this aim, we longitudinally evaluated the magnitude and kinetics of both humoral and T-cell responses by serological tests and enzyme-linked immunospot assay at 5 time points. Furthermore, we compared the course over time of the two branches of adaptive immunity to establish an eventual correlation between adaptive responses. Lastly, we evaluated putative influencing factors collected by an anonymized survey administered to all participants through multiparametric analysis. Among 984 healthcare workers evaluated for humoral immunity, 107 individuals were further analyzed to describe SARS-CoV-2-specific T-cell responses. Participants were divided into 4 age groups: &lt;40 and ≥40 years for men, &lt;48 and ≥48 years for women. Furthermore, results were segregated according to SARS-CoV-2-specific serostatus at baseline.ResultsThe disaggregated evaluation of humoral responses highlighted antibody levels decreased in older subjects. The humoral responses were higher in females than in males (p=0.002) and previously virus-exposed subjects compared to naïve subjects (p&lt;0.001). The vaccination induced a robust SARS-CoV-2 specific T-cell response at early time points in seronegative subjects compared to baseline levels (p&lt;0.0001). However, a contraction was observed 6 months after vaccination in this group (p&lt;0.01). On the other hand, the pre-existing specific T-cell response detected in natural seropositive individuals was longer-lasting than the response of the seronegative subjects, decreasing only 10 months after vaccination. Our data suggest that T-cell reactiveness is poorly impacted by sex and age. Of note, SARS-CoV-2-specific T-cell response was not correlated to the humoral response at any time point.DiscussionThese findings suggest prospects for rescheduling vaccination strategies by considering individual immunization status, personal characteristics, and the appropriate laboratory tests to portray immunity against SARS-CoV-2 accurately. Deepening our knowledge about T and B cell dynamics might optimize the decision-making process in vaccination campaigns, tailoring it to each specific immune response.
Association between the overall burden of comorbidity and Ct values among the older patients with Omicron infection: Mediated by inflammation
Authors: Wang Meixia , Mi Hongfei , Li Na , Shi Qingfeng , Sun Wei , He Tingjuan , Lin Jiabing , Jin Wenting , Gao Xiaodong , Hu Bijie , Su Chenghao , Pan Jue 
Published: March 2023

ObjectivesTo investigate the associations between the overall burden of comorbidity, inflammatory indicators in plasma and Ct values among the elderly with COVID-19.MethodsWe conducted a retrospective observational study. The results of each nucleic acid test of during hospitalization were obtained. Linear regression models assessed the associations between the overall burden of comorbidity, inflammatory indicators in plasma and Ct values among the elderly. A causal mediation analysis was performed to assess the mediation effects of inflammatory indicators on the association between the overall burden of comorbidity and Ct values.ResultsA total of 767 COVID-19 patients aged ≥ 60 years were included between April 2022 and May 2022. Patients with a high burden of comorbidity had significantly lower Ct values of the ORF gene than subjects with a low burden of comorbidity (median, 24.81 VS 26.58, P &lt; 0.05). Linear regression models showed that a high burden of comorbidity was significantly associated with higher inflammatory responses, including white blood cell count, neutrophil count and C-reactive protein. Also, white blood cell count, neutrophil count, C-reactive protein and the overall burden of comorbidity assessed by age-adjusted Charlson comorbidity index were independent risk factors for the Ct values. A mediation analysis detected the mediation effect of white blood cells on the association between the burden of comorbidity and Ct values, with the indirect effect estimates of 0.381 (95% CI: 0.166, 0.632, P &lt; 0.001). Similarly, the indirect effect of C-reactive protein was -0.307 (95% CI: -0.645, -0.064, P = 0.034). White blood cells and C-reactive protein significantly mediated the relationship between the burden of comorbidity and Ct values by 29.56% and 18.13% of the total effect size, respectively.ConclusionsInflammation mediated the association between the overall burden of comorbidity and Ct values among elderly with COVID-19, which suggests that combined immunomodulatory therapies could reduce the Ct values for such patients with a high burden of comorbidity.