bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilization of patient portals: A cross-sectional study investigating associations with mobile app quality
Authors: Yaman Noha El , Zeitoun Jad , Diab Rawan , Mdai Mohamad , Diab Razan , Kobeissi Lynn , Joud Salwa Aboul , Antoun Jumana , Bardus Marco 
Published: February 2023

Abstract
Background
Mobile apps facilitate access to patient portals and interaction with their healthcare providers. The COVID-19 pandemic accelerated this trend globally, but little evidence exists on patient portal usage in the Middle East, where internet access and digital literacy are limited. Our study aimed to explore how users utilize a patient portal through its related mobile app (MyChart by EPIC).
Methods
We conducted a cross-sectional survey of MyChart users recruited from a tertiary care center in Lebanon. We collected MyChart usage patterns, perceived outcomes, and app quality based on the Mobile Application Rating Scale (user version, uMARS) and sociodemographic factors. We examined associations between app usage, app quality, and sociodemographic factors using Pearson’s correlations, Chi-square, ANOVA, and t-tests.
Results
428 users completed the survey; they were primarily female (63%), aged 41.3 ± 15.6 years, with a higher education level (87%) and a relatively high crowding index of 1.4 ± 0.6. Most of the sample was in good and very good health (78%) and had no chronic illnesses (67%), and accessed the portal through MyChart once a month or less (71%). The most frequently used features were accessing health records (98%), scheduling appointments (67%), and messaging physicians (56%). According to uMARS completers (n = 200), the objective quality score was 3.8 ± 0.5, and the subjective quality was 3.6 ± 0.7. No significant association was found between overall app usage and the mobile app quality measured via uMARS. Moreover, app use frequency was negatively associated with education, socioeconomic status, perceived health status, and chronic conditions. On the other hand, app use was positively related to the number of physician visits and subjective app quality.
Conclusion
The patient portal usage was not associated with app quality but with some of the participants' demographic factors. The app offers a user-friendly, good-quality interface to patient health records and physicians, appreciated chiefly by females with relatively low socioeconomic status and education. While this is encouraging, more research is needed to capture the usage patterns and perceptions of male patients and those with even lower education and socioeconomic status to make patient portals more inclusive.
Improvement of Serum Ferritin Levels With Inotropic Administration in Early Phase Compared to Refractory Phase in Pediatric Patients With Septic Shock: A Preliminary Randomized Controlled Trial Study
Authors: Kanyawati Dyah , Wiradewi Anak Agung Lestari , Senapathi Tjok Gde Agung 
Published: February 2023

Abstract
Background: Septic shock, particularly protracted or refractory shock episodes, is a significant cause of morbidity and mortality in the pediatric critical care unit. According to current guidelines, only refractory cases have received inotrope administration in the therapy of septic shock; however, there haven't been many investigations to determine whether earlier administration could improve outcomes.
Methods: This randomized controlled trial compared the effects of giving epinephrine immediately after resuscitation to giving it an hour later. The surrogate endpoint of morbidity was measured by several laboratory parameters, including peripheral oxygen saturation, leukocyte count, c-reactive protein (CRP), ferritin, troponin I, and serum lactate levels. These parameters were measured at 1, 6, and 24 hours following admission.
Results: A total of 26 patients with a mean Pediatric Logistic Organ Dysfunction (PELOD) score of 8.43.0 were included in the analysis. In comparison to the refractory phase, the early phase administration of inotropic resulted in reduced leukocyte count, CRP, and serum ferritin levels at 1st and 24th hours, as well as lower serum lactate levels at 6th and 24th hours. Serum ferritin levels were considerably lower at the first hour following initial inotropic delivery, with a mean difference of 1271.1 ng/mL (p = 0.026).
Conclusion: The ferritin levels at the first hour showed that inotropic administration during the first phase provided superior results than inotropic administration during the refractory phase. To analyze the results more comprehensively, further larger scale prospective investigations are required.
Induced Magnetic Anisotropy in Co/WS 2 Bilayer
Authors: Jannati S. , Aftabi A. , Rafiei A. , Tehranchi M. M. 
Published: February 2023

Abstract
Magnetic anisotropy plays an important role in ultrathin structures and two-dimensional materials and influences their magnetoresistance (MR) response. Here, the effects of the two-dimensional WS2 layer on the structural and magnetic properties of cobalt (Co) thin film are investigated in a Co/WS2 bilayer fabricated on Si (100) substrates. The Co layer grown on the WS2 layer formed a crystal structure whereas that individual Co isolated layer is amorphous. Both prepared samples show an out-of-plane easy axis while their in-plane anisotropy is different. The magnetic hysteresis loop and MR measurements show that there is an in-plane easy axis in the Co/WS2 bilayer due to the crystallinity formation of Co grown on WS2 which is not observed in Co isolated layer. Our results represent an interface control of anisotropy in two dimensional structures.
Numerical analysis on seismic behavior of the assembled modular steel plate shear wall with inclined slots
Authors: Yang Shengchao , Jin Shuangshuang 
Published: February 2023

Abstract
This paper proposes a novel multi-grids steel plate shear wall with inclined slots (called MSPSW). This MSPSW composed of the steel plates with inclined slots, precast concrete panels, the transverse and longitudinal (T&L) connecting stiffeners, and external frame components. Smaller single plates can be used in the design and installation process since the space size of individual frames inside the frame is reduced as a result of the T&L connecting stiffeners. The direction of inclined slots in the adjacent grids is opposite, which makes the lateral resistance and stiffness close to symmetry. Numerical analysis is conducted to evaluate the seismic behavior. With the correct finite element model, finite element analysis is performed on the key parameters of MSPSW, such as the cross-sectional dimension of T&L connecting stiffeners, the thickness of steel plate, the width of inclined slots and the width of plate slot strips. The Mises distribution and development regular pattern of MSPSW are also explored. The FE numerical analysis discovered that the MSPSW increased the bearing capacity and energy consumption capacity of the members due to the installation of T&L connecting stiffeners. Additionally, the thickness required for concrete panels is lowered when the components are subjected to cyclical loads. Finally, the internal force development curves in frame beams and columns are extracted, it can be found that the internal forces become smaller, which weakens the demand of frame members. The theoretical calculation formulas of the maximum internal forces of frame beams and columns are provided.
Side effects of phytotherapeutics in cancer care - consistencies and inconsistencies in national and international databases
Authors: Büttner Juliane , Büntzel Judith , Büntzel Jens , Hübner Jutta 
Published: February 2023

Abstract
More than 80% of patients who had a cancer disease reported using phytotherapy. (8, 9)
When using herbal medicine, knowledge of potential side effects is essential for counselling the patient.
Purpose: The aim of this paper was therefore to collect information on the side effects of popular medicinal plants and to compare different official sources of information reporting on side effects of phytotherapeutics.
Methods: Four different databases were reviewed from 09 February 2021 to 01 March 2022. These were the German monographs of the German Federal Institute for Drugs and Medical Devices (BfArM), the European monographs of the EMA, the website “About Herbs” and the Red List.
One selected 171 plants of the German monographs with indications or effects that could be relevant for supportive cancer treatment.
Results: Out of 171 selected plants, only twenty plants were found in all four sources.
The compilation of the data shows a huge disparity of the number of plants listed as well as the type and frequency of side effects described. There is only one example where two sources agree: in case of Cynara cardunculus L., EMA and the Red List show the same side effects.
Conclusion: In summary, physicians should not rely exclusively on one source, but should inform themselves about side effects on several sources to ensure the best possible safety for the patient.
Since there seems to be too little data on certain medicinal plants for which no side effect has been documented, more clinical studies are needed.
Projection of Future Frequency of Severe and Extreme Droughts over Iran Country
Authors: Naderi Sohrab , Haghighi Parsa , Rouzbahani Fateme , Jahangir Mohammad Hossein , Shirvani Iman 
Published: February 2023

Abstract

Drought is one of the most destructive environmental hazards posing negative economic and social consequences. The country of Iran, which is located in the dry and semi-arid belt, is involved in many damages caused by drought every year, which makes it necessary to investigate. In this study, an attempt was made to investigate the frequency (number of occurrences) of severe and extreme droughts in the future. At first, the output of 10 climate models of the fifth report of the Intergovernmental Panel on Climate Change (IPCC) was combined using a weighting method, taking into account the model error, being used as a scenario file for the statistical downscaling of climate data in the LARS-WG. In the following, using SPI index, the frequency of severe and extreme drought was calculated. Examining the frequency of drought in different groups showed that the number of severe and extreme drought events will increase in most of them. The results showed that most groups will experience a significant increase in the frequency of extreme droughts compared to severe droughts. The percentage of changes in the number of extreme drought events was observed in most groups above 60%. Group 4 stations, which receive the highest amount of annual rainfall, along with group 3, suffered the highest increase in the frequency of extreme droughts. Considering that these areas are the main agricultural poles in the country, increasing the frequency of extreme drought can create harmful economic, social and environmental consequences.
The Effects of HIV Self-Test Knowledge on Recent HIV Testing Uptake in the Male Population in Gambia: Data analysis from 2019-2020 Demographic and Health Survey
Authors: Soe Phyumar , Johnston Lisa G. , Makuza Jean Damascene , Karim Mohammad Ehsanul 
Published: February 2023

Abstract
Background
The Gambian Ministry of Health is supportive of HIV self-testing (HIVST) and HIVST initiatives are being piloted as an additional strategy to increase HIV testing for individuals not currently reached by existing services, particularly men. The manuscript aims were to determine awareness of HIVST among Gambian men, and whether prior awareness of HIVST is associated with recent HIV testing uptake.
Methods
We used men’s cross-sectional data from the 2019–2020 Gambian Demographic and Health Survey. We employed design-adjusted multivariable logistic regression to examine the effects of HIVST knowledge on recent HIV testing. Propensity-score weighting was conducted as sensitivity analyses.
Results
Of 3,308 Gambian men included in the study, 11% (372) were aware of HIVST and 16% (450) received HIV testing in the last 12 months. In the design-adjusted multivariable analysis, men who were aware of HIVST had 1.76 times (95% confidence interval: 1.26–2.45) the odds of having an HIV test in the last 12 months, compared to those who were not aware of HIVST. Sensitivity analyses revealed similar findings.
Conclusion
Knowledge of HIVST may help increase the uptake of HIV testing among men in Gambia. This finding highlights HIVST awareness-raising activities to be an important intervention for nationwide HIVST program planning and implementation in Gambia.
Self-Perceived Performance-Based Training Needs among Middle-level Nursing Managers' in Jordan
Authors: Jalghef Mohammad Abo , Eshah Nidal , Al-Oweidat Islam , Nashwan Abdulqadir J. 
Published: February 2023

Abstract
Background: Nurse managers need to possess specific knowledge, skills, and attitudes to fulfill their roles and responsibilities and exemplify that they are competent to do their jobs. However, there is a paucity of data on the performance-based training needs of middle-level nurse managers within the Jordanian healthcare context.
Aim: The study aimed to identify the performance-based training needs of middle-level nursing managers working in Jordanian governmental hospitals and to evaluate the differences in perceived performance-based training needs based on their socio-demographic and professional characteristics.
Methods: The study utilized a descriptive cross-sectional design. The study recruited 132 nurses from three governmental hospitals in Jordan using convenience sampling. The Hennessy-Hicks Training Needs Questionnaire was used for data collection. Ethical approvals were obtained to conduct the study.
Results: The study revealed high critical, skill, and training need indices. Older nurses, nurses with more experience, and nurses who worked in specialized units had significantly lower training needs than younger nurses, nurses with lesser years of experience, and nurses who worked in outpatient departments. In addition, age, gender, prior training in nursing management, and years of experience as middle-level nurse managers significantly predicted the levels of training needed.
Conclusion: The findings reflected the need for training on several managerial competencies. Future research can help identify other personal and organizational factors affecting performance-based training needs.
Well Placement Design for Enhancing Heat Recovery from Geothermal Systems: Sensitivity Analysis using Thermo-Poro-Elastic Effects
Authors: Azim Reda Abdel 
Published: February 2023

Abstract
Geothermal energy is considered one of the most promising energy to replace oil and gas. In order to enhance this type of energy from the geothermal reservoirs, an appropriate design and evaluation tool is required to assess the stimulation treatment for improving the reservoir permeability. This paper presents an innovative approach to evaluate the well placement and designed stimulation program under thermo poroelastic coupling process using momentum, mass and energy conservation. The proposed approach is applied on a selected volume of Soultz reservoir to assess the permeability enhancement over stimulation period of more than 3 month and fluid circulation period of 14 years. In this method, the change in fracture is caused by shear slippage. The proposed stimulation model evaluates different scenarios of well placement, hydraulic fracture geometry and injection program with an objective of economic heat recovery using different fracture parameters. Results show that the thermal stress led to decreasing the produced fluid temperature across the reservoir. This is due to the fact that distributed 3-D thermal stress support in increasing the fracture opening that lead to creation of flow channeling between the injectors and producers. In addition, the result show that the presented model is capable of evaluating simulation parameters such as well placement and induced fracture geometry. This has also allowed us reducing the risk of short circulating due to excessive permeability enhancement.
Fetal echocardiography changes of the right ventricle of well-controlled gestational diabetes mellitus
Authors: Ma Ying , Sun XueSong , Liu XiaoZhi , Hu LiHua , Song Ye , Ye Xiong 
Published: February 2023

Abstract
Background There is few evidence of right ventricular (RV) function in fetuses with gestational diabetes mellitus (GDM). Therefore, the aim of this study was to assess the RV function of fetuses using routine and two-dimensional speckle-tracking echocardiography (2D STE) to determine the effects of well-controlled GDM in the third trimester.
Methods We used a Philips Epiq7C ultrasound instrument to obtain RV data sets from 63 subjects from July 2019 to February 2022. We compared the free wall thickness (FWT), fractional area change (FAC), Tei index (TEI), tricuspid annulus plane systolic excursion (TAPSE) and free wall longitudinal strain（FWLS）of the RV in mothers with well-controlled GDM and normal gestational age-matched fetuses.
Results 63 third trimester fetuses (32 GDM; 31 healthy controls) met the enrolment criteria. Significant differences in fetal RV were detected between the GDM and control groups for the FAC (36.35 ± 6.19 vs. 41.59 ± 9.11; P = 0.008) and the FWLS (-18.28 ± 4.23 vs. -20.98 ± 5.49; P = 0.021). There was a significant difference among the segmental strains of the base, middle and apex of the RV free wall in the healthy controls (P = 0.003), but in the GDM group, there was no statistical difference (p = 0.076). RV FWLS had a strong correlation with FAC (r= 0.467; P = 0.0002).
Conclusions In well-controlled GDM, there was measurable RV fetal hypertrophy and significant systolic function decline, indicating the presence of ventricular remodeling and dysfunction. 2D-STE can evaluate the RV free wall contraction in a more comprehensive way.
Validation of Automotive Centrals using Hardware in the Loop - BCM and Lights
Authors: Luciano Marley Rosa , Saldanha Rodney 
Published: February 2023

Abstract
The race for electrification and the need for innovation to attract customers has driven the automotive industry to do something different in vehicles, emerging emission control challenges and efficient technological availability are the pillars of innovation. With the need to upgrade industrial manufacturing systems, directly impacting vehicle production, established the search for new prototyping methodologies and use of virtual tools for testing, validation of components and vehicle systems are developed. The demand for electronic components control units (ECU) is growing, due to the availability of intelligence and security in today's vehicles, directly impacting their development and the performance and functionality tests. To meet this new reality, in addition to the automotive test prototypes used during development, the automotive industry has been using different virtual environments to produce, verify, and validate its vehicles. Therefore, this paper applied integration and validation using the HIL test platform, focusing on the ECU Body Control Unit (BCM), analyzing its functionalities and possible failures of the internal and external light loads. After, a brief commentary will be made exposing other test medium platforms given as the Plywood Buck (PWB), checking the reliability, flexibility, installation time, and costs of the three test platforms Software in the loop (SIL), Model in the loop (MIL), Hardware in the loop (HIL), in order to verify their advantages, challenges, and problems in the use and information to optimize the use of each platform and test medium.
Quality Grade Evaluation of Nvjin Pills Based on TCMRD and Application of Network Pharmacology to Explore the Anti- Polycystic Ovarian Syndrome Activity of Focused Compounds
Authors: Lin Lin , liu guangzhen , dexin zhang , yu fengrui , tan lejun , mu xiangrong , lin yongqiang 
Published: February 2023

Abstract
The compound Chinese herbal medicine (CCHM) is one of the most commonly used types of synergistic herbal medicine. It is based on composite herbal formula (CHF), which makes quality evaluation of this kind of traditional Chinese medicine (TCM) difficult. Taking Nvjin Pills (NJP) as an example, this study reported the development of a novel principle of analysis in CCHM. In order to improve the effectiveness of marketed drugs related active ingredients, it was necessary to designate a more unified quality evaluation standard. The core of the experimental is to prepare 3 batches of TCM reference drugs (TCMRD) using high-quality Chinese materia medica (single Chinese herbals used in the NJP). The active ingredients identified in the herbal formula including glycyrrhizic acid, cinnamaldehyde, paeonol, baicalin, hesperidin, paeoniflorin and ferulic acid were analyzed in both 3 TCMRDs and 76 batches of commercial products from 19 manufacturers by high performance liquid chromatography (HPLC) method combined with wavelength switching. NJP is a well-known Chinese patent medicine that has been widely applied for the clinical treatment of polycystic ovarian syndrome (PCOS) and other gynecological diseases. For the first time, the relationship between the components mentioned above and their pharmacological in the treatment of PCOS was explored via network pharmacology analysis. The simple prediction results of network pharmacological analysis verified the feasibility and reliability of the established quantitative analysis method for 7 compounds in NJP, which were recommended as candidate indicators for quality evaluation ultimately. Using the TCMRD as the scientific ruler, quality grade specifications of NJP were proposed by comprehensive analysis of multiple index. Accordingly, 16, 47, and 13 batches of samples were primarily rated as first-grade, second-grade and unqualified grade respectively. This study will provide a chemical basis for quality control of NJP, which is necessary in the production process of pharmaceutical development.
The influence of lifestyle habits on children with idiopathic early-onset scoliosis
Authors: Shi Fangying , Luo Dan , Luo Shujun , Zhou Xiang , Zhan Qiang 
Published: February 2023

Abstract
Objective: To analyze the relationship between lifestyle habits and scoliosis severity in children with idiopathic early-onset scoliosis (IEOS).
Method: A total of 208 children with IEOS were enrolled. Lifestyle habits and Cobb’s angles were collected for analysis.
Result: Emaciation(p=0.048), lack of sleep (p=0.017), lack of sunlight (p=0.010), lack of fish, shrimp and egg (p=0.029), exercise (p=＜0.001) and postural awareness (p=0.004) were all independent influencing factors of Cobb’s angles among IEOS Children.
Conclusion: BMI, sleep, sunlight time, fish, shrimp and egg diet, exercise, and posture awareness were all related to IEOS closely. It should be encouraged to develop children's healthy lifestyle habits.
A Hydrogenated amorphous silicon detector for Space Weather Applications
Authors: Grimani Catia , Fabi Michele , Sabbatini Federico , Villani Mattia , Calcagnile Lucio , Caricato Anna Paola , Catalano Roberto , Cirrone Giuseppe Antonio Pablo , Croci Tommaso , Cuttone Giacomo , Dunand Sylvain , Frontini Luca , Ionica Maria , Kanxheri Keida , Large Matthew , Liberali Valentino , Martino Maurizio , Maruccio Giuseppe , Mazza Giovanni , Menichelli Mauro , Monteduro Anna Grazia , Morozzi Arianna , Moscatelli Francesco , Pallotta Stefania , Passeri Daniele , Pedio Maddalena , Petasecca Marco , Petringa Giada , Peverini Francesca , Piccolo Lorenzo , Placidi Pisana , Quarta Gianluca , Rizzato Silvia , Stabile Alberto , Talamonti Cinzia , Wheadon Richard James , Wyrsch Nicolas , Servoli Leonello 
Published: February 2023

Abstract
The characteristics of a hydrogenated amorphous silicon (a-Si:H) detector are presented here for monitoring in space solar flares and the evolution of large energetic proton events up to hundreds of MeV. The a-Si:H presents an excellent radiation hardness and finds application in harsh radiation environments for medical purposes, for particle beam characterization and in space weather science and applications. The critical flux detection threshold for solar X rays, soft gamma rays, electrons and protons is discussed in detail.