bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epicardial high-resolution mapping of advanced interatrial block: Relating ECG, conduction abnormalities and excitation patterns
Authors: Ramdat Misier Nawin L. , van Schie Mathijs S. , Li Chunsheng , Oei Frans B. S. , van Schaagen Frank R. N. , Knops Paul , Taverne Yannick J. H. J. , de Groot Natasja M. S. 
Published: January 2023

BackgroundImpairment of conduction across Bachmann’s Bundle (BB) may cause advanced interatrial block (a-IAB), which in turn is associated with development of atrial fibrillation. However, the exact relation between a complete transverse line of conduction block (CB) across BB and the presence of a-IAB has not been studied.ObjectiveThe aims of this study are to determine whether (1) a complete transversal line of CB across BB established by high resolution mapping correlates with a-IAB on the surface ECG, (2) conduction abnormalities at the right and left atria correlate with a-IAB, and (3) excitation patterns are associated with ECG characteristics of a-IAB.MethodsWe included 40 patients in whom epicardial mapping revealed a complete transverse line of CB across BB. Pre-operative ECGs and post-operative telemetry were assessed for the presence of (a) typical a-IAB and de novo early post-operative AF (EPOAF), respectively. Total atrial excitation time (TAET) and RA-LA delay were calculated. Entry site and trajectory of the main sinus rhythm wavefront at the pulmonary vein area (PVA) were assessed.ResultsThirteen patients were classified as a-IAB (32.5%). In the entire atria and BB there were no differences in conduction disorders, though, patients with a-IAB had an increased TAET and longer RA-LA delay compared to patients without a-IAB (90.0 ± 21.9 ms vs. 74.9 ± 13.0 ms, p = 0.017; 160.0 ± 27.0 ms vs. 136.0 ± 24.1 ms, p = 0.012, respectively). Patients with typical a-IAB solely had caudocranial activation of the PVA, without additional cranial entry sites. Prevalence of de novo EPOAF was 69.2% and was similar between patients with and without a-IAB.ConclusionA transverse line of CB across BB partly explains the ECG characteristics of a-IAB. We found atrial excitation patterns underlying the ECG characteristics of both atypical and typical a-IAB. Regardless of the presence of a-IAB, the clinical impact of a complete transverse line of CB across BB was reflected by a high incidence of de novo EPOAF.
Screening for key genes in circadian regulation in advanced atherosclerosis: A bioinformatic analysis
Authors: Yao Jiali , Liang Jingyan , Li Hongliang 
Published: January 2023

BackgroundAtherosclerosis (AS) is the most important cardiovascular disease threatening human health, leading to adverse events such as myocardial infarction and stroke. The research on the pathogenesis and causes of AS is being improved step by step, and many factors are associated with AS. However, the relationship between circadian regulation and the pathogenesis of AS is still unclear. Our study identified 2 key genes of circadian regulation in AS by bioinformatics analysis, which provides new perspectives to understand the relationship between circadian rhythm and AS.MethodsWe downloaded samples of early and advanced AS from public databases, screened key genes by weighted gene co-expression network analysis (WGCNA) and Lasso, calculated the immune cell content of the samples using “CIBERSORT,” and analyzed the relationship between key genes and immune cells.ResultsWe obtained the most relevant core modules for advanced AS and analyzed the functions of these modules. Two circadian rhythm-related genes were obtained, which influence the immune infiltration of this late AS. ROC curves demonstrated the efficacy of key genes to differentiate between early and advanced AS.ConclusionWe identified 2 genes most associated with circadian rhythms in advanced AS, whose association with AS has not been elucidated and may become the next therapeutic target.
The South Shetland Islands, Antarctica: Lithostratigraphy and geological map
Authors: Bastías Joaquín , Chew David , Villanueva Camila , Riley Teal , Manfroi Joseline , Trevisan Cristine , Leppe Marcelo , Castillo Paula , Poblete Fernando , Tetzner Dieter , Giuliani Gregory , López Bastián , Chen Hong , Zheng Guang-Gao , Zhao Yue , Gao Liang , Rauch Anna , Jaña Ricardo 
Published: January 2023

Over the last few decades, numerous geological studies have been carried out in the South Shetland Islands, which have greatly contributed to a better understanding of its geological evolution. However, few attempts have been conducted to correlate the geological units throughout this archipelago. We present herein a review of the literature available in the South Shetland Islands, which we use to propose a lithostratigraphical correlation that constitutes a coherent stratigraphy for the main Mesozoic and Cenozoic rocks of the South Shetland Islands along with a new geological map. The lithostratigraphical correlation shows that the geological and environmental evolution comprises three main stages: 1) deep marine sedimentation from ∼164 to 140 Ma, 2) subaerial volcanism and sedimentation with a proliferation of plants and fauna from ∼140 to 35 Ma and 3) glacial and interglacial deposits from ∼35 Ma. The lithostratigraphical correlation also shows a broad geographical trend of decreasing age of volcanism from southwest to northeast, which has been previously suggested. However, this spatial age trend is disrupted by the presence of Eocene magmatism in Livingston Island, located in the centre of the archipelago. We suggest that the migration of volcanism occurred from the Late Cretaceous until the early Eocene. Subsequently, enhanced magmatic activity took place from the mid-Eocene until the Miocene, which we associate with processes related with the waning of subduction. Constraining the protolith age of the metamorphic complex of Smith Island remains challenging, yet holds key implications for the tectonic and accretionary evolution of the Antarctic Peninsula. The rocks recording the glaciation of this sector of Antarctica are well exposed in the northern South Shetland Islands and hold critical information for understanding the timings and processes that lead to the greenhouse to icehouse transition at the end of the Eocene. Finally, contemporaneous rocks to the breakup of Antarctic Peninsula from Patagonia that led to the opening of the Drake Passage and the development of the Scotia Sea are exposed in the centre and north of the South Shetland archipelago. Better constraints on the age and tectonic settings on these units may lead to further understanding the paleobiogeographical evolution of the region, which may have played an important role for speciation as a land bridge between South America and Antarctica. The dataset containing the geological map and associated information is shared as a shapefile or KML file.
The present-day stress field along the Northwest Pacific Wadati-Benioff zone constrained by focal mechanisms of moderate earthquakes
Authors: Liu Chengyu , Liu Fangbin , Cai Yin , Ni Ran , Xu Xiujie , Li Guoyi , Hao Weiduo , Tian Zhaoyang 
Published: January 2023

The present-day stress field in the northwest Pacific Wadati-Benioff Zone (WBZ) has been investigated on the basis of earthquake focal mechanism catalog covering the period from 2012 to 2021. Our catalog contains 201 focal mechanism solutions (Mw 4.0–5.9) compiled from the F-net network along three profiles (southern Kurile trench, central Japan trench and northern Izu-Bonin trench). According to the spatial variations in the stress regimes, we outlined 12 subvolumes for three profiles. Our results present that the maximum compressive stress is, slab-normal in trench-outer rise regions and nearly strike-normal and sub-horizontal in the depth range 0–70 km. At intermediate depths, a two-planar stress pattern is observed (70–200 km) in southern Kurile and central Japan trench WBZ, with the maximum compressive stress closely parallel to the slab in upper plane and slab-normal in lower plane, respectively. However, the southern Kurile trench WBZ exposes an extension stress regime in 200–300 km depth range. At depths below 300 km, northern Izu-Bonin trench WBZ shows a stress regime of pure compression. We infer the dominant forces may be the slab blending in the shallow trench-outer rise regions, slab pull and ridge push at shallow depths, and the slab resistance provided by the mantle to the penetration of the slab at deep depths. Whereas the two-planar stress pattern may be caused by the unbending of the slab, and the unusual stress state along the junction of the trench WBZ at intermediate depths may be influenced by lateral deformation due to increasing slab’s dip.
Using DInSAR to inventory landslide geological disaster in Bijie, Guizhou, China
Authors: Shen Chaoyong , Zhou Shaoqi , Luo Xuling , Zhang Yu , Liu Hui 
Published: January 2023

Landslides are very complicated natural phenomena that create significant losses of life and assets throughout China. However, previous studies mainly focused on monitoring the development trend of known landslides in small areas, and few studies focused on the identification of new landslides. In addition, karst areas, where the vegetation is dense, the mountains are high, the slopes are steep, and the time incoherence is serious, have difficulty in tracking Differential Interferometric Synthetic Aperture Radar (DInSAR) landslides. Therefore, based on DInSAR technology, we use ALOS-2 PALSAR data to conduct continuous monitoring of existing hazards and identify new geological hazards in karst areas. The major results are as follows: 1) From June 11 to 6 August 2017, it was discovered that a hidden point of landslides occurred on the 420 m northwest mountain near the town of Zongling. It was determined that the landslide hidden point had been slipping for two consecutive years, with an average slip of 6.0 cm. From 4 September 2016 to 22 January 2017, undiscovered hidden points in the landslide account were found in Yinjiazhai. On 13 September 2016 and 22 November 2016, the discovered potential hazards in the landslide log book were the mountain hazards in southwestern Shiping village, and the deformation was 7.8 cm. 2) The DInSAR monitoring results from September to November 2016 showed that large deformations occurred in the landslide area of Shiping village. During a field visit, large cracks on the surface were found. The length of surface cracks in the southwest direction of Shiping village was 2.8 m. On 13 July 2017, Shiping collapsed as a result of the collapse of the mountainous area where the disaster occurred. The average slope of the landslide in the landslide area was approximately 65°, the height was 95 m, the length and width were 150 m and 25 m, respectively, and the thickness was 5 m. The method has shown great potential in precisely identifying some new geological hazards sites, as well as tracking and monitoring the potential hazards of geological disasters listed on the landslide account.
In-situ boron isotope and chemical composition of tourmaline in the Gyirong pegmatite, southern Tibet: Implications for petrogenesis and magma source
Authors: Pei Qiuming , Ma Shaobing , Li Chenghong , Liu Fei , Zhang Yunhui , Xiao Yong , Wang Shiming , Wu Jianfei , Cao Huawen 
Published: January 2023

Leucogranitic rocks, mainly including leucogranite-pegmatite systems, have been found to be widely distributed in the South Tibetan Himalaya, and they have received considerable interest because of their significance in crustal evolution and associated rare-metal mineralization. Although the nature and geodynamic setting of the Himalayan leucogranites have been well documented by numerous studies, the pegmatites spatially associated with these leucogranites are still poorly understood. Tourmaline is a ubiquitous phase from the leucogranite to the pegmatite. We have therefore conducted in situ major and trace element and boron isotope investigations of tourmaline from the Gyirong pegmatite, synthesizing published data on the Gyirong leucogranite, to document the origin of tourmaline and its genetic implications. Two types of tourmaline (Tur-Ⅰ &amp; Tur-Ⅱ) have been identified in this contribution and they are enriched in Fe, Si and Al but depleted in Mg and Ca, with Mg/(Mg+Fe) ratios ranging from 0.22 to 0.45. Accordingly, the tourmalines belong to the alkali group and have schorl composition. Trace elements, such as Zn, Ga, V, Sc, Li, Sn, Sr, and Co in the tourmalines are relatively enriched, whereas, other trace elements record low concentrations less than 10 ppm. The trace element concentrations of tourmaline are mainly controlled by melt composition. Morphological and geochemical characteristics reflect that the tourmalines from the Gyirong pegmatite are magmatic in origin. The Gyirong pegmatitic tourmalines have S-type granitoids and pegmatites boron isotopic signatures with a tight range of δ11B values between −11.8 and −9.7‰, which is consistent with the magmatic tourmalines (Mg-poor) of the Gyirong leucogranite. This study suggests that the Gyirong pegmatite was the product of crustal anatexis and that the crustal metapelitic rocks within the Greater Himalayan Crystalline Complex were the most likely source components.
Fluid evolution and paleo-pressure recovery by Raman quantitative analysis in the Shahejie Formation of the western slope belt in Dongpu Sag, Bohai Bay Basin, China
Authors: Tang Youjun , Wu Yijun , Wang Ruyue , Huang Yahao , Xue Yifan , Chen Zhonghong , Xu Tianwu , Wang Ting , Li Hongbo 
Published: January 2023

Inorganic and organic fluids are widely found in sedimentary basins during oil and gas migration and accumulation. This research investigates two types of sandstone reservoirs with different pressure states and fluid evolution of the Shahejie Formation in the western slope belt of Dongpu Sag. Based on petrographic observations, micro-Raman spectroscopy, and fluorescent spectrometry, petroleum inclusions, CH4-bearing inclusions, and CO2-bearing inclusions were discovered in quartz-hosted minerals. The pressure–temperature–time–composition (P–T–t–X) properties of the CH4 and CO2 inclusions were obtained by quantitative Raman analysis and thermodynamic models. Minimum trapped pressure was predicted by the thermodynamic modeling of petroleum inclusions. Saffron yellow petroleum inclusions represent an early Oligocene oil-charging event (∼32–30 Ma), and the two kinds of reservoirs were all kept in moderate-overpressure conditions (average pressure coefficient: 1.26). Due to rapid uplift and denudation (Dongying movement) in the middle Oligocene in step II, crude oil degrades into CH4 and CO2 (density of CH4 gas inclusions: 0.1010–0.1339 g/cm3; density of CO2 gas inclusions: 0.450–0.612 g/cm3) and retains low-maturity (0.67–1.04%) bitumen in situ. Tectonic destruction causes the reservoir to be released to normal pressure. With the reburial of the Es3 Formation, step II entered the middle stage of oil generation again (average pressure coefficient: 0.90). However, in step I, with secondary hydrocarbons occurring, second-stage oil (performance for pale blue fluorescence in petroleum inclusions) accumulated at ∼12–0 Ma (late Miocene–Pliocene). The second oil charging event in step I remains a reservoir under high-overpressure conditions (average pressure coefficient: 1.67).
An unusual Northwest–Southeast oriented Meiyu rain belt in 2021
Authors: Huo Liwei , Guan Zhaoyong , Zhang Mengke , Jin Dachao , Wang Ji , Shi Yinglong , Wang Yi , Liu Yin , Liu Chun 
Published: January 2023

Affected by the East Asian summer monsoon, summer floods occur frequently in eastern China, causing huge economic losses and social impacts. In 2021, the precipitation anomaly during the Meiyu period in Yangtze-Huaihe River Valley (YHRV) was abnormally high, with a value of 188.0 mm, about 1.7 standard deviations above normal. However, it did not cause serious flood disasters. This was mainly due to the existence of two precipitation anomaly centers in YHRV, which shared the impact of the excessive precipitation. These two centers were located at the junction of Anhui Province and Henan Province and the junction of Jiangsu Province, Anhui Province and Jiangxi Province, respectively. And more notably, the 2021 Meiyu precipitation anomalies were distributed in a Northwest-Southeast oriented band that is very rare. During the 2021 Meiyu period, the western Pacific subtropical high (WPSH) weakened and extended westward. An anticyclonic circulation anomaly in the lower troposphere was observed over eastern China, which was found to be related to the quasi-stationary wave trains propagating eastward from Hainan Island to the northwestern Pacific by vorticity budget analysis. And the Rossby wave source term played a critical role. In addition, the tropical Atlantic anomalous warming produced convergence anomaly over the eastern Mediterranean and excited quasi-stationary wave trains propagating downstream at the mid-latitudes in upper layers through a monsoon-desert-like teleconnection. It raised the geopotential height over eastern China and thus favored the westward extension of WPSH. These large-scale circulation anomalies generated the anomalous easterly winds along the eastern coast of China and the anomalous southwesterly winds from Guangxi Province to the middle and lower reaches of the Yangtze River. Similar features can be found in the anomalous water vapor transport and the water vapor converged in the YHRV. The above-mentioned reasons jointly caused the abnormally high precipitation anomaly and its unusual pattern in the 2021 Meiyu season. This study might provide a scientific basis and clues for understanding Meiyu precipitation anomalies and disaster prevention and mitigation.
Changes of Köppen–Trewartha climate types in the Tibetan Plateau during the mid-Holocene, present-day, and the future based on high-resolution datasets
Authors: Huang Lingxin , Feng Song , Chen Jie , Deng Yajie , Chen Fahu , Huang Wei 
Published: January 2023

Tibetan Plateau (TP) is strongly impacted by accelerated anthropogenic warming that already exceeds natural variability. However, the spatial differences in climate and ecosystem response in TP between anthropogenic and natural forcings are unclear. Here, the Köppen–Trewartha climate classification is applied to examine the shifts in terrestrial climate regimes and vegetation distribution in TP by analyzing the WorldClim high-resolution downscaled climate dataset for the mid-Holocene (MH, ∼6 cal ka BP), the present-day (PD, 1960–1990), and in the future (2050s) under the Representative Concentration Pathway (RCP) 4.5 and RCP8.5 scenarios. The results show that the polar climate and the dry climate occupied more than 70% of TP area in the three periods. The MH, dominated by the natural forcing, is featured as having less distribution of dry climate than the PD. The anthropogenic change will promote a transition from a cold climate type to a warmer climate type in the 2050s. The precipitation change is responsible for the differences in climate types between the MH and PD, while warming dominates the evolution of climate types across TP in the 2050s. Moreover, vegetation types can be represented by major climate types in a large proportion of TP. In particular, polar climate regions correspond well to the areas of meadows, and the dry climate regions correspond to the steppes and deserts areas. The large changes in the climate regimes of TP suggest an extensive (shrinking) area of meadows (steppes) under natural forcing and a shrinking area of meadows under anthropogenic warming.
Complex mantle flow beneath the Luxi uplift segment of the Tanlu fault zone inferred from SKS splitting measurements
Authors: Lu Mingwen , Lei Jianshe 
Published: January 2023

To better understand the anisotropic structure and mantle dynamics in and around the Luxi uplift segment of the Tanlu fault zone in East China, we collect waveform data recorded at 47 NCISP (Northern China Interior Structure Project) portable seismic stations during November 2000 to August 2001. Using the minimum transverse energy grid-search method of SKS wave splitting measurement, effective splitting results at 35 stations are obtained. Our results show that the fast wave polarization direction (FPD) in the study area is dominated by a nearly E-W direction, with a range of 70°–116° and an average FPD of N98°E, which is generally perpendicular to the trend of the Tanlu fault zone. The splitting time varies from 0.6 to 1.5 s with an average of 0.94 s. Although there are subtle differences in FPDs of different tectonic units, it is still evident that larger splitting times amounting to ∼1.2 s are located north of the Luxi uplift, which is closely associated with the E-W horizontal flow in the big mantle wedge (BMW). In contrast, smaller splitting times are visible between the two branches of the Tanlu fault zone, indicating the existence of upwelling flow in the BMW. These complex mantle flow suggests that the BMW structure has played an important role in the deep dynamic processes beneath East Asia.
Exploring the relationship between post-contrast acute kidney injury and different baseline creatinine standards: A retrospective cohort study
Authors: Ying Jixiang , Wang Junren , Ying Zhiye , Ran Xingwu , Zeng Xiaoxi , Chen Dawei , Gao Yun , Zhong Li 
Published: January 2023

ObjectiveAccording to previous studies, the incidence of post-contrast acute kidney injury(PC-AKI) in diabetic is far higher than that in the general population. Therefore, we explored the relationship between the incidence of PC-AKI and different baseline serum creatinine (SCr) levels, and determined the relationship between PC-AKI and different types of contrast media (CMs), different doses of CM, and different examination methods in this specific population.Materials and methodsPatients with diabetes in whom CM was used between 2010 and 2020 at our institution were included. Participants were identified according to the following three schemes: Scheme 1 (n=5911), SCr was detected before and within 72 h after using CM; Scheme 2 (n=2385), SCr was detected within 24 h before and within 24–72 h after using CM; and Scheme 3 (n=81), SCr was detected within 24 h before and within 0–24, 24–48, and 48–72 h after using CM. The incidence of PC-AKI with different types of CM, incidence of PC-AKI on digital subtraction angiography (DSA) and enhanced computed tomography (CT), proportion of PC-AKI with different doses of CM, and baseline SCr at different stages of PC-AKI were compared. Multivariate logistic regression analysis was used to explore risk factors for PC-AKI.ResultsA total of 29,081 patients were included in this study. The incidence of PC-AKI in Scheme 3 (22.22%) was higher than those in Schemes 1 (6.19%) and 2 (7.71%). The incidence of PC-AKI on DSA was higher than that on enhanced CT (8.30% vs. 5.80%; P&lt;0.05). The incidence of PC-AKI in the increased-dose CM group was higher than that in the non-increased-dose CM group (7.9% vs. 5.7%; P&lt;0.01). Moreover, there were differences in baseline SCr values at different stages of PC-AKI (P&lt;0.01). Multivariate logistic regression analysis showed that hypertension, chronic kidney disease, heart failure, peripheral vascular disease, metformin, diuretics, and CM dose were risk factors for PC-AKI.ConclusionThe incidence of PC-AKI increased significantly with increasing time requirement and frequency of SCr detection. Moreover, before using CM, we should control the blood pressure and heart failure, stop using metformin and diuretics, and use CMs at the minimum dose to avoid PC-AKI.