bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and trajectories of subjective cognitive complaints and implications for patient outcomes: A prospective study of haemodialysis patients
Authors: Chan Frederick H. F. , Newman Stanton , Khan Behram A. , Griva Konstadina 
Published: February 2023

AbstractObjectivesCognitive impairment is common in haemodialysis patients and is associated with increased hospitalization and mortality. However, subjective cognitive complaints (SCCs), the self‐experienced difficulties in everyday cognitive activities, remain poorly understood. This study examined the prevalence and course of SCCs in haemodialysis patients and its longitudinal associations with sociodemographic, clinical and patient‐reported variables.DesignObservational prospective study with baseline and 12‐month follow‐up assessment.MethodsBased on a validated cut‐off point on the Kidney Disease Quality of Life Cognitive Function subscale, haemodialysis patients (N = 159; 40.3% female, mean age 53.62) were classified into cognitive complaint trajectories: (1) resilient (60.4%; no/low SCCs throughout); (2) persistent (8.8%; stable high SCCs); (3) deterioration (17.6%; from no/low to high SCCs); and (4) recovery (13.2%; from high to no/low SCCs). Sociodemographic/clinical characteristics, self‐efficacy, self‐management skills, adherence, mood and biochemical assays were measured at both assessments and compared among trajectories using mixed ANOVAs.ResultsInteraction effects indicated significant improvements in the recovery group in clinical outcomes (i.e., decreased phosphorus and calcium‐phosphorus product), self‐efficacy and mood over time. Group effects indicated significantly poorer self‐efficacy, self‐management skills and adherence in the persistent group than other trajectories across both assessments. None of the sociodemographic/clinical characteristics was associated with SCC trajectories.ConclusionsThe extent of SCCs vary over time across haemodialysis patients. Routine screening of SCCs in dialysis settings may help identifying patients at risk of poor self‐management and worse prognosis. Strategies that compensate for cognitive lapses may mitigate the perceived cognitive burden of this population.
Validation of the ‘Pelvic Pain Map’: a new self‐assessment tool for chronic pelvic pain localisation
Authors: Aibel Kelli , Moldwin Robert 
Published: February 2023

ObjectiveTo develop and validate the Pelvic Pain Map to fill a gap in the need for a localised body map of the pelvic region.Patients and MethodsThe Pelvic Pain Map incorporated input from 12 chronic pelvic pain experts across the United States, as well as patient feedback to assess face validity. Finalised diagrams are single, front‐facing images of the male and female pelvis that incorporate both abdominal and perineal views. Assessment of test–retest reliability and construct (convergent and discriminant) validity was carried out on a retrospective cohort of patients with chronic pelvic pain syndrome (CPPS) who completed the maps from January 2022 to May 2022. Other measures used in the validation process consisted of the male and female forms of the Genitourinary Pain Index (GUPI) and the short form (six item) of the Pain Catastrophising Scale (PCS‐6).ResultsTest–retest for individual map zones demonstrated moderate to excellent reliability (Cohen's kappa coefficients ranging from 0.28 to 0.64) and for total map zones demonstrated excellent reliability (intraclass correlation coefficient = 0.90). Convergent validity for individual map zones with location descriptors from the GUPI was strong (phi coefficients ranging from 0.26 to 0.79) and for total map zones was moderate (Spearman's correlation coefficient = 0.56). Discriminant validity for total map zones with separate, but related constructs from the GUPI and PCS‐6 was weakly positive (Spearman's correlation coefficients ranging from 0.27 to 0.32).ConclusionThis study suggests that the Pelvic Pain Map is a valid and reliable tool for assessing location of pain in patients with CPPS. Our findings highlight the potential utility of the Pelvic Pain Map in guiding treatment selection and monitoring therapeutic response in patients with chronic pelvic pain.
Manager‐specific shocks, financial constraints and conglomerate merger
Authors: Hong Jieying , Zhang Rui 
Published: February 2023

AbstractWe provide a theory to identify a new benefit for conglomerate mergers. In this paper, projects are subject to manager‐specific shocks. Bringing projects under the same top management in a conglomerate increases the correlation of shocks. We show that this positive correlation, in contrast to traditional wisdom, enhances a firm's ability to relax financial constraints. This is because common managerial shocks help conglomerates better take advantage of cross‐pledging possibilities. This paper also contributes to the literature by providing one of the first studies to emphasize the role of manager‐specific shocks in shaping a firm's choice to be a conglomerate or standalone.
Setting research priorities for effective management of a threatened ecosystem: Australian alpine and subalpine peatland
Authors: Rowland Jessica A. , Walsh Jessica C. , Beitzel Matthew , Brawata Renee , Brown Daniel , Chalmers Linden , Evans Lisa , Eyles Kathryn , Gibbs Rob , Grover Samantha , Grundy Shane , Harris Rebecca M. B. , Haywood Shayne , Hilton Mairi , Hope Geoffrey , Keaney Ben , Keatley Marie , Keith David A. , Lawrence Ruth , Lutz Maiko L. , MacDonald Trish , MacPhee Elizabeth , McLean Nina , Powell Susan , Robledo‐Ruiz Diana A. , Sato Chloe F. , Schroder Mel , Silvester Ewen , Tolsma Arn , Western Andrew W. , Whinam Jennie , White Matthew , Wild Anita , Williams Richard J. , Wright Genevieve , Young Wade , Moore Joslin L. 
Published: February 2023

AbstractThreatened ecosystem conservation requires an understanding of the effectiveness of management and the challenges hindering successful protection and recovery. Bringing together researchers, land managers and policymakers to identify key threats, management needs, and knowledge gaps provides a unified account of the evidence and tools needed to improve threatened ecosystem management. We undertook a research prioritization process for Australian alpine and subalpine peatlands with experts across policy, research, and management. Through individual interviews, structured group discussions, and voting, we generated 25 priority research questions that, if addressed, would enhance our capacity to conserve peatlands. Knowledge gaps spanned four topics: understanding peatland dynamics, impacts of threats, methods to manage these, and the effectiveness of management. Consistent monitoring standards, an open‐access knowledge platform and commitment to long‐term joint research and management were identified as vital. This collaboration enabled development of a shared agenda of research priorities to target knowledge gaps for informing policy and management of threatened alpine peatlands. Our findings substantiate the importance of stronger ongoing collaboration among researchers, land managers and policymakers across jurisdictions to support conservation.
YAP1::MAML2 fusions in poromatosis: A report of two patients
Authors: Mitsui Yasuhiro , Ogawa Kohei , Goto Keisuke , Fujii Tomomi , Nakamura‐Nishimura Yuki , Mashiba Kumi , Asada Hideo 
Published: February 2023

AbstractPoromatosis is a rare condition characterized by the development of multiple poromas, mainly reported in patients with a history of malignancy. Recently, frequent YAP1::MAML2 and YAP1::NUTM1 fusions have been described in poromas and porocarcinomas. To date, the molecular features of poromatosis have been investigated in one patient only, wherein the poromas harbored YAP1::MAML2 fusions. Herein, we present two additional cases of poromatosis with YAP1::MAML2 fusions. Case 1: An 81‐year‐old woman presented with nine papules on the scalp, trunk, and extremities persisting for a year. She had a history of breast cancer, with no information on the treatment. Seven papules were excised. Case 2: A 65‐year‐old woman presented with 21 lesions on her trunk and lower extremities persisting for 2 years. She had been diagnosed with breast cancer 11 years prior and had undergone partial mastectomy, radiotherapy, chemotherapy, and endocrine therapy. Four lesions were excised. All 11 lesions in both patients were histopathologically similar: anastomosing cords and strands extending from the epidermis, and poroid and cuticular cell proliferation with interspersed small ducts. The tumors showed diffuse nuclear expression of YAP1 N‐terminus and loss of YAP1 C‐terminus expression. No lesions showed NUT immunopositivity. Sanger sequencing identified YAP1::MAML2 fusions in the poromas of both patients.
Können Acne‐inversa‐Patienten ihre Läsionen mit Hilfe eines digitalen Läsionsidentifikationsschemas klassifizieren?
Authors: Schultheis Michael , Staubach‐Renz Petra , Grabbe Stephan , Hennig Katharina , Khoury Fareed , Nikolakis Georgios , Kirschner Uwe 
Published: February 2023

ZusammenfassungHintergrundDie Acne inversa (Ai) unterscheidet sich stark in ihrer klinischen Ausprägung. In der Literatur werden verschiedene Phänotypen beschrieben, die möglicherweise unterschiedliche Behandlungsmodalitäten erfordern. Ziel dieser Studie ist es, ein validiertes Schema zu entwickeln, das es Ai‐Patienten ermöglicht, ihre eigenen Läsionstypen zu identifizieren.Patienten und MethodikDie entwickelten Schemata für Ärzte und Patienten wurden in eine spezielle Software implementiert. Nach Zustimmung der Patienten dokumentierten die Ärzte die identifizierten Läsionen in der Software. Die Patienten loggten sich anschließend bequem von zu Hause aus in die Patientenversion der Software ein und wählten die Läsionen aus, die sie an sich selbst identifizierten. Anschließend wurde die Korrelation zwischen Fachleuten und Patienten getestet.ErgebnisseFür sieben Läsionstypen waren die Korrelationskoeffizienten statistisch signifikant. Eine große/starke Korrelation zwischen Patienten und Ärzten bestand für drainierende Fisteln (0,59) und doppelseitige Komedone (0,50). Bei fünf anderen Läsionstypen war die Korrelation mittel/moderat, nämlich bei entzündlichen Knoten (0,37), Abszessen (0,30), Ziehharmonika‐/ Brückennarbe (0,45), Epidermalzysten (0,33) und Pilonidalsinus (0,39).SchlussfolgerungenAi‐Patienten zeigen eine hohe Bereitschaft, ihre Erfahrungen und Daten zu teilen. Daher kann ein Selbstbewertungsschema, wie das entwickelte LISAI, ein wertvolles Instrument sein, um Patientenbefragungen durch die Identifizierung von Läsionstypen zu bereichern, zum Beispiel als Grundlage für die Phänotypisierung.
Sustainability of dermatological offices and clinics: challenges and potential solutions
Authors: Niebel Dennis , Herrmann Alina , Balzer Susanne , Hecker Christina , Koch Susanne , Luhmann Esther , Becker‐Weimann Su Youn , Tischler Max , Löffler Christin , Saha Susanne 
Published: February 2023

SummaryOngoing high consumption of resources results in exceeding the planetary boundaries. Modern healthcare systems contribute to this problem. To address this issue, this article provides an overview of various aspects of sustainable actions in medical offices and clinics that can also be applied to dermatology. Specific fields of action include energy consumption, structural measures, traffic and mobility, organization including digitalization as well as personnel and evaluation. Moreover, we discuss specific topics such as hygiene and cleansing, dermatosurgery and prescription practices. External treatments and cosmetics are discussed separately as dermatological peculiarities. Finally, we provide information on established initiatives for more sustainable health care in Germany. We aim to encourage critical reappraisal of currently established practices and to stimulate the implementation of sustainable measures.
The price of poverty: The association between childhood poverty and adult income and education in Sweden, 1947–2015
Authors: Brea‐Martinez Gabriel , Dribe Martin , Stanfors Maria 
Published: February 2023

AbstractChildhood poverty increases the likelihood of being poor as an adult. We know relatively little about this persistence of poverty in the past and whether it changed as modern welfare societies developed. This study both analyses determinants of childhood poverty and assesses the association between childhood poverty and economic outcomes in adulthood for men and women who grew up in southern Sweden, and who were followed to adulthood regardless of where in Sweden they resided. Poverty is measured in relative terms. Being raised by a single mother, foreign origin, and being raised in a context where the household head was not employed were important risk factors for childhood poverty. Growing up in relative poverty was in turn associated with low income and education in adulthood. Both the persistence and intensity of childhood poverty mattered, and so did the age during which poverty was experienced. Patterns were similar for men and women, and there was no consistent change over time as the Swedish welfare state expanded.
Positive experiences in the parent–child relationship during the COVID‐19 lockdown in Poland: The role of emotion regulation, empathy, parenting self‐efficacy, and social support
Authors: Woźniak‐Prus Małgorzata , Gambin Małgorzata , Sękowski Marcin , Cudo Andrzej , Pisula Ewa , Kiepura‐Nawrocka Eliza , Boruszak‐Kiziukiewicz Joanna , Kmita Grażyna 
Published: February 2023

AbstractDespite the impact of the COVID‐19 outbreak being largely negative on parents and children, for some families, lockdown could also bring about some positive effects, for example, increased emotional closeness, and more time for joint activity. The aim of the current study was to investigate cross‐sectionally the most important correlates of the positive experiences in the parent–child relationship among Polish mothers and fathers during the lockdown in the initial phase of the COVID‐19 outbreak. In May 2020, 228 mothers and 231 fathers completed the Brief version of the Empathic Sensitivity Questionnaire, Difficulties in Emotion Regulation Scale Short Form, Social Support Scale, Parenting Self‐Agency Measure, and Scale of Positive Experiences in Parent–Child Relationship during the COVID‐19 lockdown. Our results showed that parenting self‐efficacy and social support were the strongest correlates of positive experiences in the parent–child relationship in both mothers and fathers during the lockdown. Perspective‐taking was positively related to the positive experiences in mothers, whereas personal distress was positively associated with the positive experiences in the parent–child relationship in fathers. Our results point to factors of potential importance in designing preventive and therapeutic interventions for mothers and fathers to enhance positive experiences in the parent–child relationship during the pandemic.
The prevalence of low health literacy in undergraduate students in Pakistan
Authors: Rehman Aziz‐ur , Bin Naeem Salman , Faiola Anthony 
Published: February 2023

AbstractThis Regular Feature is based on a PhD study assessing the level of health literacy among university students in Pakistan. A cross‐sectional survey was carried out using the validated European Health Literacy Survey (HLS‐EU‐Q) and non‐parametric tests used to analyse data with the aim of determining the influence of personal determinants on health literacy skills. The findings of the study concluded that the population had a low health literacy level with limited skills in accessing, understanding, appraising and applying information for health care. Gender, age, and native languages, all had a statistically significant influence on health literacy skills. Practical implications are presented for the role of university libraries in supporting the development of health literacy in their undergraduate student populations are presented, including the need for the provision of health information in native languages.
Demarketing for sustainability: A review and future research agenda
Authors: Lawrence Jeevan , Mekoth Nandakumar 
Published: February 2023

AbstractIn the context of emerging sustainability challenges, demarketing has continued to draw the attention of academicians and practitioners globally over the past few years. It is interesting to note that demarketing is as old as marketing itself, yet its application and scope have grown from the past two decades only. Kotler and Levy, (1971) has defined demarketing as “that aspect of marketing which deals with discouraging customers in general or a certain class of customers in particular on a temporary or permanent basis”. This systematic literature review attempts to enrich the discussion on demarketing research through a systematic and comprehensive review of 64 articles published between 2000 and 2022. Using TCCM framework, we present relevant theories, research contexts, study characteristics, and methodologies used in demarketing research. Our review (1) Presents a systematic and comprehensive overview of the research in demarketing over the last two decades (2) Examines studies in demarketing within the framework of ‘triple bottom line’ approach for sustainability (3) Suggests a suitable definition of demarketing considering its exorbitant application within the sustainability context (4) Identify gaps and sets agenda for future research. Our systematic literature review found that research in demarketing has been growing considerably over the past two decades, twice as much in the last decade compared to the previous decade with spill‐over to new sectors. The literature review, through the lens of ‘triple bottom line’ approach, is able to establish that demarketing can be employed to effectively address the sustainability challenges encountered by policymakers and practitioners.
National seroepidemiological study of COVID‐19 after the initial rollout of vaccines: Before and at the peak of the Omicron‐dominant period in Japan
Authors: Arashiro Takeshi , Arai Satoru , Kinoshita Ryo , Otani Kanako , Miyamoto Sho , Yoneoka Daisuke , Kamigaki Taro , Takahashi Hiromizu , Hibino Hiromi , Okuyama Mai , Hayashi Ai , Kikuchi Fuka , Morino Saeko , Takanashi Sayaka , Wakita Takaji , Tanaka‐Taya Keiko , Suzuki Tadaki , Suzuki Motoi 
Published: February 2023

AbstractBackgroundBased on routine surveillance data, Japan has been affected much less by COVID‐19 compared with other countries. To validate this, we aimed to estimate SARS‐CoV‐2 seroprevalence and examine sociodemographic factors associated with cumulative infection in Japan.MethodsA population‐based serial cross‐sectional seroepidemiological investigation was conducted in five prefectures in December 2021 (pre‐Omicron) and February–March 2022 (Omicron [BA.1/BA.2]‐peak). Anti‐nucleocapsid and anti‐spike antibodies were measured to detect infection‐induced and vaccine/infection‐induced antibodies, respectively. Logistic regression was used to identify associations between various factors and past infection.ResultsAmong 16 296 participants (median age: 53 [43–64] years), overall prevalence of infection‐induced antibodies was 2.2% (95% CI: 1.9–2.5%) in December 2021 and 3.5% (95% CI: 3.1–3.9%) in February–March 2022. Factors associated with past infection included those residing in urban prefectures (Tokyo: aOR 3.37 [95% CI: 2.31–4.91], Osaka: aOR 3.23 [95% CI: 2.17–4.80]), older age groups (60s: aOR 0.47 [95% CI 0.29–0.74], 70s: aOR 0.41 [95% CI 0.24–0.70]), being vaccinated (twice: aOR 0.41 [95% CI: 0.28–0.61], three times: aOR 0.21 [95% CI: 0.12–0.36]), individuals engaged in occupations such as long‐term care workers (aOR: 3.13 [95% CI: 1.47–6.66]), childcare workers (aOR: 3.63 [95% CI: 1.60–8.24]), food service workers (aOR: 3.09 [95% CI: 1.50–6.35]), and history of household contact (aOR: 26.4 [95% CI: 20.0–34.8]) or non‐household contact (aOR: 5.21 [95% CI:3.80–7.14]) in February–March 2022. Almost all vaccinated individuals (15 670/15 681) acquired binding antibodies with higher titers among booster dose recipients.ConclusionsBefore Omicron, the cumulative burden was >10 times lower in Japan (2.2%) compared with the US (33%), the UK (25%), or global estimates (45%), but most developed antibodies owing to vaccination.
The application of nanopore targeted sequencing in the diagnosis and antimicrobial treatment guidance of bloodstream infection of febrile neutropenia patients with hematologic disease
Authors: Hong Mei , Peng Danyue , Fu Aisi , Wang Xian , Zheng Yabiao , Xia Linghui , Shi Wei , Qian Chenjing , Li Zixuan , Liu Fang , Wu Qiuling 
Published: February 2023

AbstractTraditional microbiological methodology has limited sensitivity, detection range, and turnaround times in diagnosis of bloodstream infection in Febrile Neutropenia (FN) patients. A more rapid and sensitive detection technology is urgently needed. Here we used the newly developed Nanapore targeted sequencing (NTS) to diagnose the pathogens in blood samples. The diagnostic performance (sensitivity, specificity and turnaround time) of NTS detection of 202 blood samples from FN patients with hematologic disease was evaluated in comparison to blood culture and nested Polymerase Chain Reaction (PCR) followed by sanger sequence. The impact of NTS results on antibiotic treatment modification, the effectivity and mortality of the patients under the guidance of NTS results were assessed. The data showed that NTS had clinical sensitivity of 92.11%, clinical specificity of 78.41% compared with the blood culture and PCR combination. Importantly, the turnaround time for NTS was <24 h for all specimens, and the pre‐report time within 6 h in emergency cases was possible in clinical practice. Among 118 NTS positive patients, 98.3% patients' antibiotic regimens were guided according to NTS results. There was no significant difference in effectivity and mortality rate between Antibiotic regimen switched according to NTS group and Antibiotic regimen covering pathogens detected by NTS group. Therefore, NTS could yield a higher sensitivity, specificity and shorter turnaround time for broad‐spectrum pathogens identification in blood samples detection compared with traditional tests. It's also a good guidance in clinical targeted antibiotic treatment for FN patients with hematologic disease, thereby emerging as a promising technology for detecting infectious disease.