bluuebunny/crossref_metadata_2025_split huggingface dataset:
Haemochromatosis patients' research priorities: Towards an improved quality of life
Authors: Romero‐Cortadellas Lídia , Venturi Veronica , Martín‐Sánchez Juan Carlos , Toska Ketil , Prince Dianne , Butzeck Barbara , Porto Graça , Milman Nils Thorm , Committee HI/EFAPH Survey , Sánchez Mayka 
Published: July 2023

AbstractBackgroundChronic diseases are associated with a range of functional and psychosocial consequences that can adversely affect patients' quality of life (QoL). Haemochromatosis (HC) is a genetically heterogeneous disorder characterized by chronic iron overload that can ultimately lead to multiple organ dysfunction. Clinical diagnosis remains challenging due to the nonspecificity of symptoms and a lack of confirmatory genotyping in a substantial proportion of patients. Illness perception among HC patients has not been extensively investigated, lacking relevant information on how to improve their QoL.MethodsWe present the results of the first worldwide survey conducted in nearly 1500 HC respondents, in which we collected essential demographic information and identified the aspects that concern HC patients the most.ResultsOut of all the participants, 45.3% (n = 676) voiced their concern about physical and psychological consequences such as HC‐related arthropathies, which can ultimately affect their social functioning. A similar proportion of patients (n = 635, 42.5%) also consider that better‐informed doctors are key for improved HC disease management. Taking a patient‐centred approach, we expose differences in patients' disease perspective by social and economic influences.ConclusionsWe identify potential targets to improve patients' health‐related QoL and reflect on strategic measures to foster gender equity in access to health resources. Finally, we make a call for a highly coordinated effort across a range of public policy areas to empower participants in the HC research process and design.Patient or Public ContributionNearly 1500 patients with hereditary HC responded to an anonymized online survey in which research and clinical priorities were addressed regarding this chronic and rare disease.
Group work dynamics and the role of leadership in face‐to‐face and online second language classes
Authors: Hiromori Tomohito 
Published: July 2023

AbstractThis study aimed to investigate how having a student in a leader role impacts group work dynamics (GWD) in face‐to‐face (FTF) and online communication. A total of 144 pre‐intermediate English learners worked in groups of three on a picture‐description task under one of the four conditions: with or without a leader in FTF or online settings. All exchanges were recorded, transcribed, and analyzed using a GWD measuring instrument to explore the process of GWD. The results showed that GWD scores were lower in the online condition than in FTF, particularly when there was no designated leader. Furthermore, when comparing the GWD scores of the leader‐role students and other students, leaders consistently scored higher across most GWD characteristics, regardless of communication mode. This study suggests that assigning a leader‐role student can facilitate group work activities, especially in online communication. It sheds light on students’ behaviors in group work contexts and highlights the importance of leadership in promoting effective group work.
A review and comparative perspective on health benefits of probiotic and fermented foods
Authors: Ibrahim Salam A. , Yeboah Philip J. , Ayivi Raphael D. , Eddin Abdulhakim S. , Wijemanna Namesha D. , Paidari Saeed , Bakhshayesh Rea V. 
Published: July 2023

SummaryFermented foods such as yogurt, kefir and sauerkraut have been part of the human diet throughout history and have gained attention in recent years due to their immense health and nutritional benefits. As a result, fermented foods are considered biofuel for the human microbiome which helps to boost the immune system. Fermented foods are those foods and beverages that are produced by employing specific microbial‐based fermentation aids such as yeasts and bacteria, particularly lactic acid bacteria (LAB). Through controlled enzymatic reactions, these microbial cultures transform food components as substrates into value‐added products promoting various healthy fermentative activities. These microbes in fermented foods also produce compounds that can inhibit food spoilage and pathogenic microorganisms, thereby extending the product shelf of fermented products. Probiotics are live microbiota with beneficial health properties, prevent gastrointestinal diseases and modulate the human microbiome. Thus, foods that are fermented by certain strains of probiotic bacteria that exhibit evidence of health benefits are referred to as probiotic fermented foods. This review describes fermented and functional foods, probiotics and their relationship to human health. In addition, we offer our perspective on the distinct differences between probiotic and fermented foods to promote awareness for consumers and key stakeholders regarding these highly functional and nutritionally fermented food products.
Moving the mountain: Stigma removal, strategic industry, and the Indian civilian nuclear industry
Authors: Gopakumar K. V. , Ram Mohan M. P. , Awasthi Kshitij 
Published: July 2023

AbstractThe present study examines stigma removal in the context of strategic industries. Strategic industries are critical from a national interest perspective and may not be able to engage in conventional stigma management strategies, such as concealment, dilution and coopting stakeholders, identified in extant literature. The present in‐depth qualitative study of the Indian civilian nuclear energy industry, a strategic industry within the Government of India, identifies two strategies, namely dependency reduction and category repositioning through responsible behaviour, employed in order to eradicate a global level stigma. The study concludes with implications for strategic industries and stigma management literature.
Third language phonological acquisition: Understanding sound structure in a multilingual world
Authors: Wang Di , Nance Claire 
Published: July 2023

AbstractThe field of third language acquisition has gathered increased attention over the last three decades. However, phonological acquisition in an L3 is still relatively understudied within the field, despite there likely being over a billion people regularly using an L3 worldwide. In this paper, we review experimental and theoretical studies of sequential L3 acquisition to date and aim to give implications for future L3 phonological acquisition research, laying the groundwork for advances in this area. According to the reviewed studies, it is necessary to adapt previous second language phonology models (i.e. SLM/SLM‐r, PAM/PAM‐L2, L2LP) into future L3 phonological research. Additionally, it is essential to expand the research scope and time scale to reflect linguistic diversity, age and education background of participants, and the processes of learning.
A hybrid ontology‐based semantic and machine learning model for the prediction of spring breakup
Authors: De Coste Michael , Li Zhong , Khedri Ridha 
Published: July 2023

AbstractRiver ice breakups carry the potential for high flows and flooding and are of great interest to accurately predict. A challenge in forecasting these events is the management of the massive amounts of data associated with an ice season. This study couples ontological and machine learning models in a new hybrid modeling framework to predict spring breakup on a national scale. The Ice Season Ontology sorts the data and allows for a user‐friendly means of analyzing any ice season, providing insight on which variables are most and least central. With this, a refined variable selection is able to be made for machine learning models. The most successful developed model, a random forest, produced highly accurate forecasts when applied to a national scale case study, with a mean absolute error of 10.85 days and an R2 of .884. This new modeling framework provides a means for decision‐making support for river bound communities and a new methodology for modeling applications in other fields.
The fadXDEBA locus of Staphylococcus aureus is required for metabolism of exogenous palmitic acid and in vivo growth
Authors: Kuiack Robert C. , Tuffs Stephen W. , Dufresne Karine , Flick Robert , McCormick John K. , McGavin Martin J. 
Published: July 2023

AbstractIn Staphylococcus aureus, genes that should confer the capacity to metabolize fatty acids by β‐oxidation occur in the fadXDEBA locus, but their function has not been elucidated. Previously, incorporation into phospholipid through the fatty acid kinase FakA pathway was thought to be the only option available for S. aureus to metabolize exogenous saturated fatty acids. We now find that in S. aureus USA300, a fadX::lux reporter was repressed by glucose and induced by palmitic acid but not stearic acid, while in USA300ΔfakA basal expression was significantly elevated, and enhanced in response to both fatty acids. When cultures were supplemented with palmitic acid, palmitoyl‐CoA representing the first metabolite in the β‐oxidation pathway was detected in USA300, but not in a fadXDEBA deletion mutant USA300Δfad, which relative to USA300 exhibited increased incorporation of palmitic acid into phospholipid accompanied by a rapid loss of viability. USA300Δfad also exhibited significantly reduced viability in a murine tissue abscess infection model. Our data are consistent with FakA‐mediated incorporation of fatty acids into phospholipid as a preferred pathway for metabolism of exogenous fatty acids, while the fad locus is critical for metabolism of palmitic acid, which is the most abundant free fatty acid in human plasma.
Voiceless and vulnerable: An existential phenomenology of the patient experience in 21st century British hospitals
Authors: Ramsey Sarah M. , Brooks Jane , Briggs Michelle , Hallett Christine E. 
Published: July 2023

AbstractCurrent health policy, high‐profile failures and increased media scrutiny have led to a significant focus on patient experience in Britain's National Health Service (NHS). Patient experience data is typically gathered through surveys of satisfaction. The study aimed to support a better understanding of the patient experience and patients' expression of it through consideration of the aspects of the patient experience on NHS wards which are by their nature impossible to capture through patient satisfaction surveys. Existential phenomenology was used to develop an in‐depth exploratory narrative, expressed through the voices of the participants. Data collection involved in‐depth face‐to‐face interviews with 12 purposively sampled participants, with analysis by means of hermeneutics. Though the individuality of each experience was apparent and cannot be overemphasised, common factors emerging from the data included uncertainty and unexpectedness, suffering and finitude, the futility of feedback and bureaucracy and absurdity. Overall, participants demonstrated how their individual personalities and expectations affected their response both to illness or injury and to their hospital admissions, highlighting feelings of vulnerability and voicelessness as a response to hospitalisation. The findings of this study provide useful insight into the patient experience on British hospital wards, and the value of an existential–phenomenological approach is demonstrated.
Parallel selection of loss‐of‐function alleles of Pdh1 orthologous genes in warm‐season legumes for pod indehiscence and plasticity is related to precipitation
Authors: Yong Bin , Zhu Weiwei , Wei Siming , Li Bingbing , Wang Yan , Xu Nan , Lu Jiangjie , Chen Qingshan , He Chaoying 
Published: July 2023

Summary
Pod dehiscence facilitates seed dispersal in wild legumes but results in yield loss in cultivated legumes. The evolutionary genetics of the legume pod dehiscence trait remain largely elusive.
We characterized the pod dehiscence of chromosome segment substitution lines of Glycine max crossed with Glycine soja and found that the gene underlying the predominant quantitative trait locus (QTL) of soybean pod‐shattering trait was Pod dehiscence 1 (Pdh1). A few rare loss‐of‐function (LoF) Pdh1 alleles were identified in G. soja, while only an allele featuring a premature stop codon was selected for pod indehiscence in cultivated soybean and spread to low‐precipitation regions with increased frequency. Moreover, correlated interactions among Pdh1's haplotype, gene expression, and environmental changes for the developmental plasticity of the pod dehiscence trait were revealed in G. max.
We found that orthologous Pdh1 genes specifically originated in warm‐season legumes and their LoF alleles were then parallel‐selected during the domestication of legume crops.
Our results provide insights into the convergent evolution of pod dehiscence in warm‐season legumes, facilitate an understanding of the intricate interactions between genetic robustness and environmental adaptation for developmental plasticity, and guide the breeding of new legume varieties with pod indehiscence.
The impact of COVID‐19 on the well‐being of Victorian children born with cleft lip and/or palate
Authors: Branson E. K. , Collins B. , McGrath R. , Anderson V. , Kilpatrick N. , Crowe L. M. 
Published: July 2023

AbstractBackgroundA longitudinal cohort study was established to investigate the well‐being of children born with cleft lip and/or palate (CL/P) during the COVID‐19 pandemic, in Victoria, Australia.Materials and MethodsThe Royal Children's Hospital cleft service database was used to identify children aged between 4 and 17 years old born with an isolated CL/P. Families of eligible children who consented to participate were asked to complete the Strengths and Difficulties Questionnaire (SDQ) between October and December 2020 and again 6‐month later. SDQ results from typically developing Australian children during the COVID‐19 pandemic were utilized from a previously published study.Results63 parents completed the baseline questionnaire, with 44 completing the 6‐month follow‐up. For participants at baseline, the mean age was 8.9 years, with 55% male. All outcome domains of the SDQ improved between baseline and timepoint 2, with the difference in total difficulties scores being statistically significant, indicating a reduction in total difficulties at timepoint 2, associated with the easing of COVID‐19 restrictions. When compared with the Australian population during the COVID‐19 pandemic, Victorian children born with CL/P had lower SDQ scores for all difficulties outcome domains, with statistically significant results for conduct problems, hyperactivity, peer problems and total difficulties, indicating fewer difficulties for children born with CL/P.ConclusionsChildren born with CL/P experienced fewer difficulties when compared with the typically developing Australian population during the COVID‐19 pandemic. The level of restrictions imposed because of the pandemic also had little influence on the well‐being of these children.
Geochemical evidence of provenance diversity in Holocene sandy land of Qinghai Lake Basin in the north‐eastern margin of Qinghai–Tibet Plateau and its implications for climate change
Authors: Ding Zhiyong , Lu Ruijie , Liu Xiaokang , Wu Yongqiu , Chen Dongxue 
Published: July 2023

ABSTRACTThe Qinghai Lake Basin, located in the north‐eastern Tibetan Plateau, is crucial for understanding the East Asian monsoon evolution and its interaction with westerlies. Palaeoclimatic studies in this region since the Holocene have primarily focused on interpreting proxy significance from sediments, resulting in being highly controversial. However, exploring palaeoclimate evolution through sediment provenance and proxy integration remains rare. This study analysed the elemental geochemical properties of two fluvial–lacustrine–aeolian profiles in Hudong Sandy Land, east of the Qinghai Lake Basin, and compared these with published modern basin sediments and extensively investigated Late Quaternary aeolian deposits. It was found that Hudong Sandy Land sediments exhibit similar geochemical compositions to other modern basin sediments, primarily consisting of SiO2, Al2O3 and CaO. Contrary to previous understanding, lacustrine sediments in the Hudong Sandy Land are closer to the upper continental crust average than aeolian deposits. Geochemical ratios and parameters suggested that Hudong Sandy Land sediments primarily derived from mixed source rocks of felsic igneous, quartzose sedimentary and intermediate igneous provenances. A comparison with published elemental geochemical data from the basin reveals distinct sediment sources during different periods in the Hudong Sandy Land. From 9.6 to 4.0 ka bp, Hudong Sandy Land hosted numerous lake environments, with sediments displaying a dominant role in sedimentary recycling and reworking, implying a continuously stronger East Asian summer monsoon. During 8.2 to 5.1 ka bp, the Hudong Sandy Land was a fluvial depositional sink for sediments from the Dabanshan Mountains. Bedrock clastic material generated by intense erosion and monsoonal runoff transport contributed to Hudong Sandy Land sedimentation, indicating the East Asian summer monsoon's peak since 9.6 ka bp. After 4.0 ka bp, thick aeolian sands accumulated in the Hudong Sandy Land, primarily derived from Lake Qinghai sediments due to declining water levels, indicating that westerlies and East Asian winter monsoon dominated the basin, with a weaker East Asia summer monsoon. This study facilitates a deeper understanding of the interaction between the East Asia summer monsoon and East Asia winter monsoon/westerlies.
Associations between power, stress, and dominance in romantic relationships during the COVID‐19 pandemic: Examining curvilinear and within‐person effects
Authors: Gresham Abriana M. , Peters Brett J. , Karantzas Gery C. , Cameron Linda D. , Simpson Jeffry A. , DiGiovanni Ana M. 
Published: July 2023

AbstractTwo key processes in romantic relationships—power and dominance—can contribute to relationship disruption, but the association between these variables is complex. Elucidating the association between power and dominance during the COVID‐19 pandemic is particularly important given the economic, social, and health‐related stressors that pose a risk to relationship health. We examined associations between power, stress, and dominance by recruiting 1813 participants to complete an initial online survey at the beginning of the COVID‐19 pandemic. Participants were contacted 10 and 22 months later to complete follow‐up surveys. Results revealed two main effects: individuals who had greater relationship power and experienced more COVID‐19‐related stressors than other people engaged in more dominance behaviors. A significant curvilinear effect revealed that at low levels of power, power was not associated with dominance behaviors. However, once power surpassed low levels, individuals with more power engaged in more dominance behaviors. Finally, people engaged in more dominance behaviors when they experienced more power and stress compared to their own average (i.e., within‐person effects) during the pandemic. Implications for theories of power, dominance, and relationship disruption and distress are discussed.
Collective bargaining and technological innovation in the EU15: An analysis at establishment level
Authors: da Silva Bichara Julimar , Monsueto Sandro E. , Viñas Ana I. 
Published: July 2023

AbstractIn this paper, we study the relationship between unionisation and workplace innovation in a cross‐country and multisectoral approach. This is an important and controversial issue in the industrial relation literature; however, the empirical literature on the links between innovation and unionism is rather scarce and results are mixed and ambiguous, both in theory and in empirical practice. The European Company Survey (Eurofound), with data for establishments in 15 European Union countries, is used employing a probit model. Our results contribute to the debate by showing that the adoption of technology not only increases when the company performs collective bargaining but also when the relationship between wage bargaining and innovation adoption is not linear, being more significant in cases where bargaining occurs at the regional/national level.
Discrete representations of finitely generated groups into PSL(2,R)${\rm PSL}(2,\mathbb {R})$
Authors: Liang Hao 
Published: July 2023

AbstractWe prove a factorization theorem for Fuchsian groups similar to those proved by Agol and Liu for 3‐manifold groups. As an application, we build Makanin–Razborov diagrams, which parameterize the collection of all discrete representations from an arbitrary but fixed finitely generated group to . We define a new class of groups called ‐discrete limit groups and then use the factorization theorem to obtain useful information about this class of groups.
Banach spaces of continuous functions without norming Markushevich bases
Authors: Russo Tommaso , Somaglia Jacopo 
Published: July 2023

AbstractWe investigate the question whether a scattered compact topological space K such that has a norming Markushevich basis (M‐basis, for short) must be Eberlein. This question originates from the recent solution, due to Hájek, Todorčević and the authors, to an open problem from the 1990s, due to Godefroy. Our prime tool consists in proving that does not embed in a Banach space with a norming M‐basis, thereby generalising a result due to Alexandrov and Plichko. Subsequently, we give sufficient conditions on a compact K for not to embed in a Banach space with a norming M‐basis. Examples of such conditions are that K is a zero‐dimensional compact space with a P‐point, or a compact tree of height at least . In particular, this allows us to answer the said question in the case when K is a tree and to obtain a rather general result for Valdivia compacta. Finally, we give some structural results for scattered compact trees; in particular, we prove that scattered trees of height less than ω2 are Valdivia.
Enterobacterales
draft genome sequences: 15 historical (1998–2004) and 30 contemporary (2015–2016) clinical isolates from Pakistan
Authors: Crawford Matthew A. , Lascols Christine , Lomonaco Sara , Timme Ruth E. , Fisher Debra J. , Anderson Kevin , Hodge David R. , Morse Stephen A. , Pillai Segaran P. , Sharma Shashi K. , Khan Erum , Allard Marc W. , Hughes Molly A. 
Published: July 2023

ABSTRACT

The continued emergence and spread of antimicrobial resistance among pathogenic bacteria are ever-growing threats to health and economy. Here, we report the draft genomes for 45
Enterobacterales
clinical isolates, including historical and contemporary drug-resistant organisms, obtained in Pakistan between 1998 and 2016: 5
Serratia
, 3
Salmonella
, 3
Enterobacter
, and 34
Klebsiella
.