bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybridization Domestication and Molecular Cytogenetic Characterization of New Germplasm of Thinopyrum intermedium with smGISH at Northeastern China
Authors: Liu Yizhuo , Song Weiwei , Song Anning , Wu Chunfei , Ding Jiarui , Yu Xiaoning , Song Jia , Liu Miaomiao , Yang Xinyuan , Jiang Changtong , Zhao Haibin , Li Xinling , Cui Lei , Li Hongjie , Zhang Yanming 
Published: April 2023

Abstract
Thinopyrum intermedium (2n = 6x = 42, StStJrJrJvsJvs), a perennial relative of wheat, is resistant or tolerant to biotic and abiotic stresses, making it an important genetic material for breeding perennial crops. It is also known as intermediate wheatgrass (IWG). The morphological performance, chromosome composition, and yield components of 24 newly developed perennial germplasm, designated 19HSC-Q and 20HSC-Z lines, were investigated from 2019 to 2022. Six lines of 19HSC-Q had higher values of yield component traits, such as thousand-kernel weight, grains per spike, and tiller number than that of Th. intermedium. 19HSC-Q14, 19HSC-Q18 and 19HSC-Q20 had the best agronomic traits with grain number per spike and thousand-kernel weight of 115, 97, and 102 and 7.674, 7.516, and 7.371 g in 2022, respectively. Three 20HSC-Z lines had been growing for two years that the grain number per spike was 116, 88, and 81, and the thousand-kernel weight was 7.146, 6.523, and 5.916 g, respectively. The results of sequential multicolor GISH analysis revealed that the Jvs-subgenome of Th. intermedium were divided into two karyotypes, type-I Jvs with 3 pairs of chromosomes and type-II Jvs with 4 pairs of chromosomes. Both IWG and 24 perennial germplasm had the similar chromosome composition but the translocation between subgenome chromosomes were detected in some lines with prominent comprehensive agronomic traits, such as 19HSC-Q6, 19HSC-Q11, 19HSC-Q18, and 20HSC-Z. The chromosome aberration could be distinguished into two types: the large fragment translocation with Jr-St, Jvs-St, Jr-IIJvs, and Jvs-Jr and the small fragment introgression of St-IJvs. Results of this study provide important materials for the next breeding cycle of cold resistant perennial wheatgrass.
Age and developmental stage specific Bioaccumulation of Copper during acute toxicity of Copper sulphate of two freshwater Fishes Rohu (Labeo rohita) and Mrigal (Cirrhinus mrigala)
Authors: Afridi Azam Jan , Zuberi Amina , Yousafzai Ali Muhammad , Zaidi Farrah 
Published: April 2023

Abstract
The widespread use of Copper resulted in chronic toxicity, triggering adverse health consequences for the aquatic organism. To investigate bioaccumulation of Copper, acute toxicity test / Median lethal concentration (LC50/96h)) of copper sulphate was performed at four aged group, and developmental stages viz fertilized egg to larvae, swim-up fry, advance fry, and fingerling of two freshwater fishes Rohu (Labeo rohita) and Mrigal (Cirrhinus mrigala). Each group was exposed to water born copper toxicity in selected glass aquaria. Resulted values of Median lethal concentrations (LC50/96h) of copper sulphate at Embryonic and larval, Swim-up fry, Advance fry, and Fingerling stages for Labeo rohita were 0.37, 0.75, 1.07, and 1.34 ppm and for Cirrhinus mrigala were 0.48, 0.94, 1.36, and 1.52 ppm respectively. Copper was analyzed in the whole bodies of first three developmental stages Viz; Embryonic and larval, Swim-up fry, Advance fry, while at fourth i-e at Fingerling stage five tissues Viz; gills, liver, kidney, skin, and muscle were selected. The resulted bioaccumulation order of copper at four developmental stages were Fingerling > Advance fry > Swim-up fry > Embryonic and larval stages for both species. At fourth, fingerling stage bioaccumulation of Copper was resulted in order of gills > liver > skin > kidney > muscle tissues for Rohu, and in order of liver > gills > kidney > skin > muscle tissues of Mrigal. This study provides baseline information for toleration of maximum quantity of Copper at four developmental stages. We recommend the pretreatment of industrial effluent before discharges into freshwater bodies.
Self and Mother Referential Processing in Phonological False Memory
Authors: Zhang Shuhui , Chen Zhu , Li Bingbing 
Published: April 2023

Abstract

It is well documented that self-referential processing enhances semantic false memory, yet the effect of self-referential processing on phonological false memory remains unclear. The current study used phonological DRM and self-reference paradigms to examine whether phonological false memory was affected by self and mother referential processing. In the current two experiments, we presented participants the Deese–Roediger–McDermott lists together with their own name, his/her mother’s name or “Lu Xun”. The results revealed that true recognition rates were not different between self-reference and mother-reference conditions and both were higher than the other-reference condition; there were no significant differences in false recognition rates among the self-reference, mother-reference and other-reference conditions. These results suggest that there are significant self-reference and mother-reference effects in true memory and no self-reference and mother-reference effects in phonological false memory. The findings are discussed in terms of theories of the self and mother reference effects and phonological false memory.
Metabolic syndrome and its associated factors among dyspeptic patients: A facility based cross-sectional study design
Authors: Nigatie Marye , Melak Tadele , Asmelash Daniel. , Alemayehu Ermiyas , Ashagrie Agenagnew , Worede Abebaw 
Published: April 2023

Abstract
Objective The aim of study is used to assess the association between Metabolic syndrome and its associated factors among dyspeptic patients at Tefera Hailu Memorial General Hospital, Sekota, North-East Ethiopia.Methods The study was a cross-sectional study design from March 01/2022 to May 30/2022. The study subjects were selected by convenient sampling technique. The data were entered into Epi. data 3.1 and analyzed using SPSS version 25. Logistic regression analysis was conducted and, P-value < 0.05 was used as a statistically significant variable.Results Our study included 228 study participants. The total prevalence of metabolic syndrome among study participants was 23.2%. Metabolic syndrome was statistically significantly associated with fasting blood glucose level(AOR: 15.965, 95% CI: 7.605–33.515), P < 0.001. The median serum level of low-density lipoprotein cholesterol (p < 0.001), triglyceride (P = 0.036), SBP(< 0.001and total cholesterol (P < 0.001) was a statistically significant difference between H. pylori positive and negative study participants.
Long non-coding RNA CASC2 inhibits malignant progression of endometrial cancer by negatively regulating mir-103a-3p/mir-107
Authors: Jia-ning Huo , Zi-hao Wang , Yi-bing Li , Yun-zheng Zhang , Xue-lian Chen , Xin Pan , Xiao-xin Ma 
Published: April 2023

Abstract
Background Long noncoding RNA CASC2 was first discovered as a tumor suppressor gene in endometrial cancer, but its mechanism is unclear. The purpose of this study was to investigate the effect of CASC2 on endometrial cancer and its mechanism.Methods We determined the expression of CASC2, miR-103a-3p/miR-107, PLAG1, and IGF2 in endometrial cancer and normal endometrial tissues through TCGA database and PCR analysis. It was subsequently confirmed that CASC2 and miR-103a-3p/miR-107 affect the biological behavior of endometrial cancer cells through a ceRNA mechanism. In addition, we confirmed this in vivo with a nude mouse xenograft model.Results The expression of CASC2 in endometrial cancer tissues is significantly downregulated, and this downregulation is related to tumor differentiation and affects tumor prognosis. Through cell experiments, it was found that CASC2 combined with miR-103a-3p/miR-107 can affect the biological behavior of endometrial cancer cells. Further research showed that CASC2, as the ceRNA of miR-103a-3p/miR-107, affected the expression of downstream target genes. The above cell experiments were also confirmed with in vivo experiments in a nude mouse xenograft model.Conclusions CASC2 combined with miR-103a-3p/miR-107 affects the malignant process of endometrial cancer. This study provides a new direction for the diagnosis and treatment of endometrial cancer.
Mir-302a-3p targets RUNX1 to inhibit the malignancy and epithelial-mesenchymal transition in endometrial cancer cells
Authors: Huo Jia-ning , Wang Zi-hao , Pan Xin , Li Yi-bing , Ma Xiao-xin 
Published: April 2023

Abstract
Background Runt related transcription factor 1 (RUNX1), a member of the RUNX family, is differentially expressed in various tumors. MicroRNA (Mir)-302a-3p, a member of the mir-302 family, is expressed at various levels in many tumors. We hypothesized that mir-302a-3p and its target RUNX1 jointly affected biological behavior of endometrial carcinoma.Method The binding sites of RUNX1 and mir-302a-3p were predicted by biological software and verified by luciferase assay. Real-time quantitative PCR was used to verify the expression of mir-302a-3p and RUNX1 at mRNA level. Western blotting was used to analyze the expression of RUNX1 and EMT-related proteins. The expression of RUNX1 was also validated by immunohistochemistry. The combined effect of Mir-302a-3p and RUNX1 on endometrial cancer was assessed in in vivo and in vitro models.Results RUNX1 was upregulated in endometrial cancer tissues, consistent with results from the TCGA database. RUNX1 knockdown can inhibit proliferation and promote apoptosis of endometrial cancer cells, as well as affect the G0-G1 phase of the cell cycle. Our previous results indicate that mir-302a-3p is down-regulated in endometrial cancer tissues. Bioinformatics analysis predicted a binding site between mir-302a-3p and RUNX1, which was validated by dual luciferase assays. We confirmed by quantitative real-time PCR and western blot that overexpression or knockdown of mir-302a-3p can affect the expression of RUNX1.Similarly, overexpression of mir-302a-3p inhibited proliferation, promoted apoptosis, and affected the G0-G1 phase of the cell cycle in endometrial cancer cells; these effects were more profound with co-transfection of mir-302a-3p agomir and shRUNX1.Further, mir-302a-3p and RUNX1 affected EMT in endometrial cancer, and the tumor-reducing effect of both RUNX1 knockdown and mir-302a-3p overexpression were confirmed in vivo.Conclusions Our results demonstrate that downregulation of mir-302a-3p promotes malignant biological behaviors and EMT in endometrial cancer cells by targeting RUNX1, and the miR-302a-3p/RUNX1 axis may be a potential therapeutic target for endometrial cancer.
Photon Blockade in the Fully Coupled Tripartite Hybrid System
Authors: Yan Shurui , Wang Yueming 
Published: April 2023

Abstract
We studied the fully coupled tripartite hybrid system with a two-level atom embodied in cavityopto-mechanical system. Applying the Shriever-Wolff approximation to the Hamiltonian of the sys-tem, we reached a fully diagonal effective Hamiltonian as well as its eigensystems. Thus the systemhas two turnable parameters including the detunings between the atom, cavity resonant frequencyand the driving laser field. We investigated the single- and two-photon blockade effects of the sys-tem under different detunings and cavity field driving strength using the probabilistic amplitudemethod and the quantum master equation method. The two-level atom plays an important role forthe photon blockade effect because it induces a shift of the cavity resonant frequency and a moreadjustable parameter for the system.
Model-Free Cooperative Optimal Output Regulation for Linear Discrete-Time Multi-Agent Systems Using Reinforcement Learning
Authors: Wu Beining , Wu Wei 
Published: April 2023

Abstract
In this paper, an off-policy model-free algorithm is presented for solving the cooperative optimal output regulation problem for linear discrete-time multi-agent systems. First, an adaptive distributed observer is designed for each follower to estimate the leader's information. Then, a distributed feedback-feedforward controller is developed for each follower to solve the cooperative optimal output regulation problem utilizing the follower's state information and the adaptive distributed observer. Based on reinforcement learning method, an adaptive algorithm is presented to find the optimal feedback gains via online data collecting from system trajectory. By designing a Sylvester map, the solution to the regulator equations is calculated via data collected from the optimal feedback gain design steps, and the feedforward control gain is found. Finally, an off-policy model-free algorithm is proposed to design the distributed feedback-feedforward controller for each follower to solve the cooperative optimal output regulation problem. A numerical example is given to verify the effectiveness of this proposed approach.
Numerical Study of High Temperature Heat Pipe to Suppress Gas Explosion
Authors: Gui Xiaohong , Wang Shengwei , Huang Junhui , Zhu Ziqiang , Zhao Chenyang 
Published: April 2023

AbstractAs a new type of heat transfer element, high temperature heat pipe has high heat transfer efficiency and broad prospects in suppressing gas explosion shock wave and flame. In this paper, the mechanism and effect of gas explosion suppression in high temperature heat pipe were analyzed by theoretical analysis and numerical simulation. ANAYS FLUENT was used to simulate the propagation process of gas explosion, and the simulation results were in good agreement with the experimental results. The influence of high temperature heat pipe on gas explosion propagation characteristics under different working conditions was studied. The results show that the flame propagation speed of gas explosion in the roadway with high temperature heat pipe is reduced, which will have nearly twice the time delay, the peak value of flame temperature is reduced, and the maximum overpressure of gas explosion in the roadway after the high temperature heat pipe is far lower than the maximum overpressure when the high temperature heat pipe is not laid. The layout of high temperature heat pipes in the roadway has different degrees of influence on the explosion suppression effect, and the best explosion suppression effect is achieved when the high temperature heat pipes are placed at 10 m intervals and inclined at 90°. The application of high temperature heat pipe technology to restrain gas explosion has certain feasibility, and the research results are of great significance to the safe and efficient production of coal mines.
The Usefulness of Humeral Intraosseous Infusion Performed by Rapid Response Vehicle Staff in Patients with Cardiac Arrest: A Single-Centre, Retrospective Study
Authors: Takamatsu Jumpei , Tsubota Hiroshi , Okajima Atsushi , Nakajima Hajime , Nakata Masatoshi , Kang Jinkoo , Yasue Yuichi 
Published: April 2023

Abstract
Background Humeral intraosseous infusion (IOI) is often performed in the prehospital setting by rapid response vehicle staff. IOI is used to administer extracellular fluid products and resuscitation drugs such as adrenaline to patients with trauma and cardiac arrest when venous channels are difficult to secure. However, in Japan, its usefulness is not well recognised, and it is rarely performed aggressively. This study aimed to demonstrate that humeral IOI is superior to the conventional peripheral venous infusion (VI) in cardiac arrest.Methods Among cases that received emergency care by rapid response vehicle staff from 2017 to 2022, 363 patients with cardiac arrest were transported to our institution with well-defined timing information. Patients were divided into humeral IOI and peripheral VI groups and compared in terms of age, sex, time from dispatch to contact and arrival at the hospital, time spent at the scene, distance travelled, type of injury, and return of spontaneous circulation (ROSC). Incident reports related to IOI during this period were also investigated. Continuous variables were compared by analyses of variance. Categorical data were compared using the chi-square test.Results There were no significant differences in terms of age, sex, time (min) from onset to dispatch (IOI: 3.19 ± 0.88, VI: 3.85 ± 0.60, P = 0.54), contact (IOI: 13.53 ± 0.96, VI: 14.11 ± 0.66, P = 0.62), and hospital arrival (IOI: 30.37 ± 1.15, VI: 30.51 ± 0.79, P = 0.92), time spent at the scene (IOI: 8.96 ± 0.35, VI: 8.25 ± 0.24, P = 0.1), or mileage (km) (IOI: 9.23 ± 0.46, VI: 9.58 ± 0.32, P = 0.53). There were significantly more cases of ROSC in the IOI group than in the VI group (IOI: yes 47: no 70, VI: yes 41: no 95, P = 0.001). There were no incident reports, such as unnoticed complications, continued infusions, and needle stick injury.Conclusions Humeral IOI required the same amount of time to perform as conventional peripheral VI but showed better outcomes in terms of ROSC. Humeral IOI is a valid infusion route until the completion of primary care. This simple and reliable procedure should be feasible for future prehospital emergency care.
The renaissance of the building stone in defining the architectural identity of the Jordanian city - (Amman city)
Authors: Shagin Musa , Awwad Bassam Abu , Safran Mansour 
Published: April 2023

Abstract
The material of building stone in this picturesque nature is a valuable treasure in the hands of man, and the value of building stone that man discovered since ancient times is because he believes that this material is the truth that preserves his artistic achievements over time and reflects the face of civilization and the thought of peoples, and man has invested in stone caves and in The manufacture of hunting and self-defense tools, and he used them in their basic function to bear the weights in building his dwellings, cities, and temples, and in the details also in the walls, ceilings, knots, doors, windows, stone columns, their bases, and muqarnas. And when we start today the stage of architectural design, we touch on the art of architecture and full knowledge of all the technical details in order to succeed in this work, and we read about the history of the architecture of civilizations and peoples for thousands of years and the stages of their development until our modern era, which reflected their religious and social philosophy and its continuous development, and it is a science that combines the past And the present with its primary components and has an extension and has no limits. It is the science of the building block over time that left us diligence to delve into this field, especially in our field of work after we left the academic period. The science of building stone reflects the civilized and cultural face of the peoples in general and the Arab peoples in particular.
Modular light-emitting diode shelving systems for scalable optogenetics
Authors: Gangemi Christina G. , Janovjak Harald 
Published: April 2023

Abstract

Optogenetic experiments rely on the controlled delivery of light to diverse biological systems. Impressive devices have been recently developed to simulate cells and small animals with multiple wavelengths and intensities. However, existing hardware solutions are often limited to a single sample holder and their design and cost can further limit scalability. This chapter describes an illumination system that is modular (through the use of accessible components) and scalable (through a shelving structure and low cost). Assembly and operation require no or minimal electrical engineering or programming expertise. Multi-intensity, wavelength and temporal experiments can be performed in dozens of small and large samples. This chapter also introduces methods for temperature and light intensity measurements towards appropriate illumination conditions. This work aims to provide a greater level of accessibility and complementary opportunities for large scale optogenetics in a broad range of biological samples.
Context-aware Multi-modal Recommendation Model based on Deep Auto-encoder
Authors: Gupta Rohan , Patel Arjun , Wilson Krik , Brown Kellen 
Published: April 2023

Abstract
With the exponential growth of data in the era of big data, recommendation systems have become essential in e-commerce. Accurate prediction of users' ratings of products is the key problem for personalized recommendation services. The current research in recommendation systems is mainly divided into three types: content-based, collaborative filtering, and hybrid recommendation. However, the traditional matrix decomposition algorithm faces difficulties in adapting to the current complex environment. In recent years, deep learning techniques have made great breakthroughs in recommender systems. We propose a multi-modal recommendation architecture based on self-encoder to effectively fuse textual and visual modal data, contextual features, and textual information to assist recommendation and significantly improve video recommendation performance. The proposed video recommendation model can effectively avoid the situation that the recommendation results cannot be obtained due to the lack of unimodal data. Specifically, the architecture comprises three key components: (1) a contextual feature extraction module based on convolutional neural networks to extract contextual information from textual data; (2) a multi-modal fusion module that fuses the contextual features with visual features to effectively integrate the complementary information across modalities; and (3) a self-encoder-based recommendation module that incorporates the fused features to generate personalized recommendations for users. Experimental results on several real datasets with distinctive features demonstrate the effectiveness of the proposed architecture. The proposed model significantly outperforms state-of-the-art recommendation models on the video recommendation task.