bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pyschological traumatic perinatal experiences during the Covid-19 pandemic, epigenetic hypothesis and protective suggestions
Authors: İsbir Gözde Gökçe , Turner Jonathan , Gabbianelli Rosita 
Published: August 2023

AbstractWhether Covid-19 will continue with different viral mutations it will last is not yet known. For this reason, correct management of the process becomes important in order to ensure that future generations are least affected by this experience. This literature review aims to discuss hypotheses for the epigenetic effect of perinatal experiences affecting mental health during the Covid-19 pandemic and protective intervention recommendations. A comprehensive understanding of epigenetic mechanisms can allow early risk detection and directed prevention and intervention strategies. There is a need for epigenetic studies that monitor the short- and long-term effects in women/infants going through the perinatal period during the Covid-19 pandemic. Epigenetic studies are costly and take a long time. At this time where the pandemic is still ongoing, it is predicted that the negative effects will be reduced by predicting epigenetic effects and taking protective approaches in line with the results obtained from previous studies. These will be possible with the collective work of multidisciplinary team members. Mental health care professionals should receive training on epigenetics in the perinatal period and should be able to integrate it into counseling processes.
Culture-directed antibiotics in peritoneal dialysis solutions: a systematic review focused on stability and compatibility
Authors: Ling Chau Wei , Sud Kamal , Patel Rahul , Peterson Gregory , Wanandy Troy , Yeoh Siang Fei , Van Connie , Castelino Ronald 
Published: August 2023

AbstractBackgroundThis systematic review summarises the stability of less commonly prescribed antibiotics in different peritoneal dialysis solutions that could be used for culture-directed therapy of peritonitis, which would be especially useful in regions with a high prevalence of multidrug antibiotic-resistant strains.MethodsA literature search of Medline, Scopus, Embase and Google Scholar for articles published from inception to 25 January, 2023 was conducted. Only antibiotic stability studies conducted in vitro and not recently reviewed by So et al.were included. The main outcomes were chemical, physical, antimicrobial and microbial stability. This protocol was registered in PROSPERO (registration number CRD42023393366).ResultsWe screened 1254 abstracts, and 28 articles were included in the study. In addition to those discussed in a recent systematic review (So et al., Clin Kidney J 15(6):1071–1078, 2022), we identified 18 antimicrobial agents. Of these, 9 have intraperitoneal dosing recommendations in the recent International Society for Peritoneal Dialysis (ISPD) peritonitis guidelines, and 7 of the 9 had stability data applicable to clinical practice. They were cefotaxime, ceftriaxone, daptomycin, ofloxacin, and teicoplanin in glucose-based solutions, tobramycin in Extraneal solution only and fosfomycin in Extraneal, Nutrineal, Physioneal 1.36% and 2.27% glucose solutions.ConclusionsPhysicochemical stability has not been demonstrated for all antibiotics with intraperitoneal dosing recommendations in the ISPD peritonitis guidelines. Further studies are required to determine the stability of antibiotics, especially in icodextrin-based and low-glucose degradation products, pH-neutral solutions.Graphical abstract
Methods and standards of pollen monitoring—significance of pollen measurements at different altitudes
Authors: Bastl Maximilian , Bastl Katharina , Dirr Lukas , Berger Markus , Berger Uwe 
Published: August 2023

Abstract
Background
The measurement of pollen concentrations has been performed according to various protocols in recent decades. In all approaches the following questions were of importance: the positioning of the measuring device (whether at roof or nose level), the reliability as well as the comparability of measurements.

Methods
Current methods for pollen measurements and previous studies on measurement heights are presented and compared.

Results
The most widely used device is the Hirst pollen and spore trap. Its data is widely used for pollen information, pollen prediction models, and clinical studies. The position of the trap at roof level remains the current standard as the pollen concentrations correlate best with “real world” situation and regional symptom data.

Conclusion
The guideline for the detection of pollen and spores for allergy networks (EN 16868:2019-09) in Europe was an important step towards standardization. Modern, automated measurement methods are still in experimental stage in terms of validation and comparability. Harmonization of data from different measurement methods is a future challenge.
In Vitro Assessment of Antiviral, Antimicrobial, Antioxidant and Anticancer Activities of Ulvan Extracted from the Green Seaweed Ulva lactuca
Authors: Maray Sahar O. , Abdel-Kareem Mohamed S. M. , Mabrouk Mona E. M. , El-Halmouch Yasser , Makhlof Mofida E. M. 
Published: August 2023

AbstractMarine macroalgae contain a variety of bioactive substances that have many different uses. Ulvan, a sulfated hetero-polysaccharide isolated from Ulva lactuca, has been described and investigated for its antioxidant, antiviral, antibacterial, and cytotoxic action against the cell lines PC-3 and A-549. The yield of polysaccharides was 26.53 ± 0.32. (Algal dry weight) with 2.23% uronic acid. According to HPLC estimates, the polysaccharide isolated from Ulva lactuca contains the neutral sugars glucose, rhamnose and galactose, as well as fructose, and melibiose. The FT-IR spectrum of ulvan revealed bands at 1227.73 cm− 1 and 1333.97 cm− 1, respectively, indicative of sulfate esters and uronic acids. This study came to the conclusion that Ulva lactuca ulvan (ULU) contains beneficial elements that can stop the development of cancer cells. The lowest viability of PC-3 cells, which occur at the highest concentration of ULU (500 µg/ml), was 17.58% with an IC50 of 237.02 ± 6.84 µg/ml, while the lowest viability of lung carcinoma cells was 13.91% with an IC50 of 124.38 ± 4.78 µg/ml. This indicates that the cytotoxicity against the prostate cancer cell line was lower than that against the lung carcinoma cell line. Although ULU has no activity against adenovirus, it had antiviral efficacy against HAV-10. ULU has been shown to have antibacterial efficacy against pathogenic bacteria, including Staphylococcus aureus ATCC25923 Escherichia coli ATCC 8739, Bacillus subtilis ATCC 6633, Enterococcus faecalis ATCC 29,212, Pseudomonas aeruginosa ATCC 9027, Klebsiella pneumonia ATCC 13,883, Pseudomonas fluorescent ATCC13525 and Streptococcus agaloctiae ATCC13813. The polysaccharide, meanwhile, has limited antioxidant action.
The Increasing Complexity of Guideline-Directed Medical Therapy for Heart Failure with Reduced Ejection Fraction and Challenges for Real-world Implementation
Authors: Soh Bing Wei Thaddeus , Langille Jaimie , O’Brien Kathryn , Glasgow Jacinta , Murray Siobhan , Abbas Syed , O’Connor Cormac , Arnous Samer , Kiernan Thomas 
Published: August 2023

AbstractThe latest guidelines for heart failure with reduced ejection fraction (HFrEF) recommend concurrent treatment with four drug classes to improve patient outcomes. While physicians likely have the skillsets needed to navigate the complexities of multiple drug interactions, HF nurse prescribers lack experience needed to implement the latest guideline-directed medical therapy (GDMT). As nurse-led HF services continue to expand, implementing GDMT is essential for gold-standard care. We describe and compare the abilities of physician-led and nurse-led HF clinics in implementing GDMT in HFrEF within the outpatient setting. A retrospective multi-centre cohort study was performed on the pharmacotherapy patterns of HFrEF patients attending either a physician-led or nurse-led HF clinic in 2021. Pharmacotherapy patterns of prescribing on the pillars of HFrEF therapy were collected: ACEi/ARB/ARNi, BB, MRA, SGLT2i. 164 and 231 HFrEF patients were reviewed in a physician-led and nurse-led group respectively. Compared to physicians, there were significantly lower rates of MRA (42.0% vs 62.8%, P < 0.001) and SGLT2i (7.8% vs 24.4%, P < 0.001) prescribed by nurses. Most patients seen by physicians were treated with three drug classes (45.7%) versus two drug classes (50.2%) when seen by nurses. Ongoing gaps in GDMT implementation are driven by the suboptimal MRA and SGLT2i use. Patients seen by nurses were treated with less drug classes and less likely to be treated with MRA and SGLT2i compared to physicians. These findings highlight the ongoing difficulties autonomous nurse prescribers face in HF prescribing and the need for further educational supports.
The Mythological Origins of Renaissance Florence
Authors: Chernetsky Irina 
Published: August 2023

In this book, Irina Chernetsky examines how humanists, patrons, and artists promoted Florence as the reincarnation of the great cities of pagan and Christian antiquity – Athens, Rome, and Jerusalem. The architectural image of an ideal Florence was discussed in chronicles and histories, poetry and prose, and treatises on art and religious sermons. It was also portrayed in paintings, sculpture, and sketches, as well as encoded in buildings erected during the fourteenth and fifteenth centuries. Over time, the concept of an ideal Florence became inseparable from the real city, in both its social and architectural structures. Chernetsky demonstrates how the Renaissance notion of genealogy was applied to Florence, which was considered to be part of a family of illustrious cities of both the past and present. She also explores the concept of the ideal city in its intellectual, political, and aesthetic contexts, while offering new insights into the experience of urban space.
Benefit–Cost Analysis of Increased Funding for Agricultural Research and Development in the Global South
Authors: Rosegrant Mark W. , Wong Brad , Sulser Timothy B. , Dubosse Nancy , Lybbert Travis J. 
Published: August 2023

AbstractThis paper conducts a benefit–cost analysis of expanding agricultural research and development (R&D) in the Global South. We extend a recent modeling exercise that used IFPRI’s IMPACT model to estimate the investments required to reduce the global prevalence of hunger below 5%. After 35 years, the increased funding is estimated to increase agricultural output by 10%, reduce the prevalence of hunger by 35%, reduce food prices by 16%, and increase per capita incomes by 4% relative to a counterfactual where funding continues to rise on historical trends. Using an 8% discount rate, the net present value of the costs of agricultural R&D are estimated at $61 billion for the next 35 years, while the net present benefits in terms of net economic surplus (the sum of consumer and producer surplus) are estimated at $2.1 trillion. The central estimate of the benefit–cost ratio (BCR) is 33, consistent with previous research documenting high average returns to agricultural research and development. The central BCR reported in this study places the intervention at the 91st percentile of all previous Copenhagen Consensus BCRs in agriculture, and 87th percentile for all BCRs regardless of sector. Agricultural R&D is likely one of the best uses of resources for the remainder of the Sustainable Development Goals and decades beyond.
Predictive puericulture in Argentina: The Plataforma Tecnológica de Intervención Social and the reproduction of Latin eugenics
Authors: Hagerty Alexa , Aranda Florencia , Jemio Diego 
Published: August 2023

AbstractIn April 2018, as the Argentine Congress debated decriminalizing abortion, local media revealed that public-health officials in a northern province had deployed an algorithmic system to predict teenage pregnancy. Public response to the technology quickly became entangled in society-wide debates about reproductive rights. Both proponents and detractors of the algorithmic system framed the technology as novel and cutting-edge. However, this paper argues for an analysis of the system not as a form of innovation or rupture but as a continuation of historical forms of biopolitical governance in Argentina, particularly puericultura, a eugenic theory of child rearing.
Characterization of Spinal Cord Injury Patients for Arm Functional Restoration through Nerve Transfer
Authors: Jack Andrew , Rajshekar Mithun , Witiw Christopher D. , Curran Matthew W.T. , Olson Jaret L. , Morhart Michael J. , Jacques Line , Chan K. Ming 
Published: August 2023

ABSTRACTIntroduction:Traumatic spinal cord injuries (tSCI) are common, often leaving patients irreparably debilitated. Therefore, novel strategies such as nerve transfers (NT) are needed for mitigating secondary SCI damage and improving function. Although different tSCI NT options exist, little is known about the epidemiological and injury-related aspects of this patient population. Here, we report such characteristics to better identify and understand the number and types of tSCI individuals who may benefit from NTs.Materials and Methods:Two peripheral nerve experts independently evaluated all adult tSCI individuals < 80 years old admitted with cervical tSCI (C1–T1) between 2005 and 2019 with documented tSCI severity using the ASIA Impairment Scale for suitability for NT (nerve donor with MRC strength ≥ 4/5 and recipient ≤ 2/5). Demographic, traumatic injury, and neurological injury variables were collected and analyzed.Results:A total of 709 tSCI individuals were identified with 224 (32%) who met the selection criteria for participation based on their tSCI level (C1–T1). Of these, 108 (15% of all tSCIs and 48% of all cervical tSCIs) were deemed to be appropriate NT candidates. Due to recovery, 6 NT candidates initially deem appropriate no longer qualified by their last follow-up. Conversely, 19 individuals not initially considered appropriate then become eligible by their last follow-up.Conclusion:We found that a large proportion of individuals with cervical tSCI could potentially benefit from NTs. To our knowledge, this is the first study to detail the number of tSCI individuals that may qualify for NT from a large prospective database.
Sustainable product development in aeroengine manufacturing: challenges, opportunities and experiences from GKN Aerospace Engine System
Authors: I. Hallstedt Sophie , Isaksson Ola , Nylander Johanna W. , Andersson Petter , Knuts Sören 
Published: August 2023

Abstract
A radical shift in technology is necessary to enable future air transport solutions. Sustainability targets for aeroengine manufacturing mean more than reducing CO2 and NOX. The future will open up possibilities and bring new challenges when introducing hybrid- and electrical propulsion technologies using new materials, technology solutions and new business models. This article reports on findings from a longitudinal study and many years of collaboration between researchers and industry experts, where a first-tier aeroengine manufacturer transforms their product development capabilities to enable sustainable product development. The article highlights some activities undertaken and identifies critical challenges and opportunities remaining for a manufacturer of next-generation aeroengine solutions. It is argued that the challenge for aeroengine manufacturers to develop new-generation propulsive technologies will require a systemic change in the undertaking of design and development. The opportunities of sustainable technologies are evident yet require: (1) means to tighter integrate business and technology development, (2) the ability to quantify and assess sustainability impacts of different concept solutions, and (3) means to utilise natural resources, alloys and materials for a circular and life-cycle optimised solution.
Medical Colonialism and the Power to Care: Unsettling Participatory Inclusion in the Settler-State Care Paradigm
Authors: Boodman Eva 
Published: August 2023

AbstractThis article looks at the implications of medical colonialism in Canada for the feminist concept of care. Because medical colonialism is an ongoing material relation where “good” settler care cannot be separated from Indigenous dispossession, I defend the view that care and violence can be coextensive and suggest that a decolonial care ethic needs to disrupt the directionality of care as flowing from agential carers toward colonized care-receivers. I argue that contemporary medical colonialism should indeed be understood as a form of care if structural harm is to be addressed in practice, and trouble the notion of inclusion at work in some contemporary theories of care. By finding demands for assimilationist “participatory inclusion” in examples of government-run, Indigenous-serving care services, I caution against the implicit settler-colonial assumptions in notions of “caring democracies” and “caring societies” on the welfare-state model. If care is political and can participate in the normative pressures of civic assimilation, then to “decolonize” it through refraction, disruption, infiltration, disconnection, re-appropriation, and resistance also means to “decolonize” citizenship and civic life in the interests of Indigenous self-determination, rather than presumed inclusion in settler-state processes.
Contracting Costs, Covenant-Lite Lending, and Reputational Capital
Authors: Badoer Dominique C. , Emin Mustafa , James Christopher M. 
Published: August 2023

AbstractUsing a large sample of leveraged loans, we provide evidence that, despite having fewer creditor control rights, covenant-lite (Cov-Lite) loans have similar recovery rates and significantly lower spreads than loans with maintenance covenants. We find that the propensity to borrow Cov-Lite is related to various proxies for the reputational capital of a borrowing firm’s private equity sponsor. We construct a simple model to illustrate the relationship between reputational capital, covenants, and loan spreads in the leveraged loan market. Our model illustrates how reputational capital can substitute for covenants in mitigating agency costs of debt, leading to lower loan spreads for Cov-Lite loans.
Silent Heritage: Investigating Ruxton's Nigeria Collection at the Horniman Museum and Gardens
Authors: Martin Fleur 
Published: August 2023

AbstractMuseums which display all of their colonial collections are rare, and those which offer clear information on collection provenances and colonial histories in displays are rarer still. Absence and silence surrounding the colonial past in Europe's museums places them at odds with international pressure to account for the custodianship of colonial-era collections. This is examined here through investigating the silent heritage of the Ruxton Nigeria Collection, held at the Horniman Museum and Gardens in London. Ruxton collected as a military official during Britain's conquest of Nigeria. His collection is typical of assemblages throughout European ethnographic museums, dominated by “everyday” material heritage, not the “treasures” of elites which monopolise restitution discourse. How can provenance research be conducted upon quieter collections dating from the colonial era with little accompanying documentation? What are the potential impacts of such research upon restitution debates? From the available evidence around the Ruxton collection, it is clear that silences are more fundamental than just a matter of archival gaps, and if silences remain even after provenance research (which many museums are unable to conduct on all of their collections), then we need to question not only why and how collections are displayed, but how museums justify having them at all.
Concerns, perceived risk, and hesitancy on COVID-19 vaccine: a qualitative exploration among university students living in the West Bank
Authors: Veronese Guido , Mahamid Fayez , Bdier Dana 
Published: August 2023

Abstract
The current study aimed to explore Palestinian university students’ perceptions and concerns about COVID-19 vaccination hesitancy. Our sample comprised 50 university students selected using snowball sampling techniques from Palestinian universities in the West Bank, Palestine. Thematic content analysis was conducted to identify the main themes of semi-structured interviews with students. The results of the thematic content analysis yielded four main themes: Students’ perceptions and concerns on COVID-19 vaccinations, perceived risks of vaccination, experiences related to vaccination, and causes of vaccination hesitancy. Participants expressed concerns and doubts about the vaccine’s safety, showing high hesitancy and scepticism; they also reported different causes for COVID-19 vaccination hesitancy in the Palestinian context, such as the lack of confidence in vaccines, false beliefs about vaccines, and peculiar political instability and conflict of the Palestinian territories enduring a military occupation undermining the health system’s capacity to respond to the COVID-19 outbreak appropriately. Health authorities and policymakers are urgently called to invest in and potentiate awareness campaigns to change the diffuse people’s stereotypes related to the COVID-19 vaccine in the Palestinian territories.
Exploring Australian night shift workers’ food experiences within and outside of the workplace: a qualitative photovoice study
Authors: Leung Gloria KW , Huggins Kate E , Bonham Maxine P , Kleve Sue 
Published: August 2023

AbstractObjective:Night shift workers are at a 20 to 40 % increased risk of metabolic diseases, which may be associated with their disrupted eating patterns. This qualitative study explores factors that influence night shift workers’ eating habits, within and outside of the workplace, to identify target areas for health promotion strategies.Participants and Setting:Eligible participants resided in Australia, working at least three overnight shifts per month.Design:The photovoice method was used, whereby participants were asked to take photos that represent their typical eating habits. These photos were incorporated as prompts in a semi-structured interview, which explored factors influencing eating habits on night shifts and days-off and perceptions and enablers to healthy eating.Results:Ten participants completed the study. Thematic analysis generated four main themes, which were mapped onto the Social Ecological Model (SE Model). Aligned with the SE Model, our results show night shift workers’ eating habits are influenced by intrapersonal, interpersonal and (work) organisational levels. Participants reported that at work, appropriate food preparation facilities are required to enable healthy food choices. Poor shift work rostering leads to prolonged fatigue on days-off, limiting their ability and motivation to engage in healthy eating. Consequently, night shift workers seem to require additional supports from their social networks and enhanced food literacy skills, in order to adopt/ maintain healthy eating behaviours.Conclusions:Night shift work creates individual and environmental barriers to healthy eating, which are present during and outside of work. Health promotion strategies for this population should include multiple approaches to address these barriers.