bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disruptive innovation in effective learning systems: the impact of personalized instructor-created software-aided assessments to increase retention and knowledge
Authors: Nadan Joseph S. , Walton Abram , Tabaei Behzad , Bryant Charles Edward , Shah Natalie 
Published: January 2023

Purpose
This paper aims to propose an innovative method for deploying a personalized instructor-created software-aided assessment system, that will disrupt traditional learning environments by allowing students to confidentially and with indirect supervision from the instructor, assess their knowledge and ability to achieve the course outcomes.

Design/methodology/approach
Through empirical evaluation in real-world educational settings, the authors examine the impact of augmenting human activity in the classroom with an innovative software platform to transform the learning process.

Findings
Findings indicate that this software-aided assessment system effectively augments human interactivity by providing timely instructor-designed feedback to increase knowledge retention and skillsets.

Practical implications
This study has shown that incorporating disruptive innovation through the use of software-aided assessment systems increases the effectiveness of the faculty in the classroom and enhances student learning and retention. Thus, a transformative software-aided assessment system design that incorporates artificial intelligence into the learning pathway should be pursued. These software-aided assessments are disruptive innovation as they are formative, frequent and require little direct involvement from the instructor.

Originality/value
To the best of the authors’ knowledge, this study is the first of its kind to incorporate artificial intelligence into the assessment process by analyzing results of pilot programs at several universities. The results demonstrate how using software-aided transformative assessments in various courses have helped instructors assess students’ preparedness and track their learning progress. These software-aided systems are the first step in bringing disruptive innovation to the classroom as these software-aided assessment instruments rapidly assess learners’ knowledge and skills based on short, easily created, multiple-choice tests, with little direct engagement from the faculty.
Mobile payment service quality: a new approach for continuance intention
Authors: Hijazi Rawa , Abu Daabes Ajayeb , Al-Ajlouni Mohammed Iqbal 
Published: January 2023

PurposeThis paper assesses the continuance intention (CI) for mobile-based payment (M-payment) services following the COVID-19 pandemic by combining the self-efficacy construct with the electronic service quality model.Design/methodology/approachThis exploratory, cross-sectional research employs qualitative and quantitative research methods; specifically, a questionnaire and interviews. A total of 403 Jordanian participants completed valid questionnaires. Mediation and moderation evaluations assessed the M-payment service quality (MPSQ), self-efficacy and health concerns (HC) to determine CI.FindingsThe results verify the significance of MPSQ and self-efficacy in developing CI and show the mediating influence of self-efficacy between MPSQ and CI. Moreover, HC negatively impact the self-efficacy/CI link.Practical implicationsThis research benefits M-payment service providers seeking to secure customer loyalty via improved M-payment services. The behavioral intention investigation will provide rich information about potential customers' CI and illuminate areas for development.Originality/valueThis research makes an original contribution to the existing M-payment literature by investigating the impact of customers' perception of service quality on their CI to utilize M-payment services, balanced with self-efficacy and HC.
Are principles of recovery-oriented practice evident in staff and service user perspectives on seclusion?
Authors: Stíobhairt Antaine , Staunton David , Guerin Suzanne 
Published: January 2023

Purpose
This paper aims to explore the extent to which principles of recovery-oriented practice are evident in the published perspectives and experiences of health professionals and service users on seclusion in adult mental health services.

Design/methodology/approach
A systematic review informed by PRISMA guidelines was conducted, drawing from four databases, which were searched in August 2018 and August 2022. Only original empirical studies rated as having “major” relevance were included. Data were extracted from 31 studies and qualitatively synthesised through deductive analysis using recovery principles as themes.

Findings
There was limited evidence of perceptions of seclusion being being consistent with recovery principles, with greater evidence of perceptions that directly opposed them. Studies of service user perspectives highlighted this more often than staff perspectives. The findings highlight paradoxical relationships between care and control and conflicting rights and emphasise the need to openly acknowledge the complexity of seclusion and its interface with recovery.

Research limitations/implications
This review was developed in line with international best practice and the protocol was registered. Using a search string with only three components maximised sensitivity during searches and minimised the risk of relevant literature being missed. Limitations include the focus on studies where the full text was published in English.

Originality/value
This review makes a unique contribution, highlighting that, to the best of the authors’ knowledge, no studies to date have explicitly explored the perspectives and experiences of staff and service users on the use of seclusion in the context of recovery-oriented practice. The findings are relevant to clinical practice, policy and future research, including amending procedures and practices to partially reconcile seclusion and recovery where the seclusion is deemed necessary.
When do M&As with Fintech Firms Benefit Traditional Banks?
Authors: Collevecchio Francesca , Cappa Francesco , Peruffo Enzo , Oriani Raffaele 
Published: January 2023

AbstractIn the last decade, fintech has emerged in the financial sector, introducing numerous innovations that have severely impacted traditional banks. To respond to fintech firms and meet the new needs of consumers, banks seek to align their offerings by integrating fintech knowledge through mergers and acquisitions (M&As) within an open innovation framework. However, it is still not clear when exactly M&As with fintech firms benefit banks. This paper examines the contingency factors that make M&As beneficial for acquirer banks by using a holistic approach that considers the type of firm, type of deal and the context in which M&As occur. We analysed the effect produced by acquirer sustainability, minority acquisitions and institutional distance between the fintech and the bank's country of incorporation by applying an event study methodology using cumulative abnormal returns to gauge effects on expected performance. We have shown which are the conditions that allow us to maximize the acquirer bank's expected performance. Our research advances the scientific understanding of M&A contingency factors, and more generally of open innovation, in the specific context of fintech and banks. Moreover, we provide managers and policymakers with initial advice on the effects fintech M&As have on traditional banks, showing that they can be beneficial under specific conditions.
Good conduct in a context of rationing: A case study of how frontline professionals deal with distributive dilemmas of novel gene therapies
Authors: Wadmann Sarah , Hauge Amalie Martinus , Emdal Navne Laura 
Published: January 2023

AbstractClassical dilemmas of how to distribute limited resources have been rekindled by the rise of advanced, high‐cost therapies. Building on a case study of a novel gene therapy in neuropaediatric care, this article explores the dilemmas that explicit priority setting can create for frontline professionals and develops a typology of professionals’ responses to these dilemmas. Despite political attempts to centralise priority setting and spare health professionals from having to consider treatment costs at the ‘bedside’, this study shows that concern for economic efficiency and budget control nonetheless need to be handled and balanced against other accountabilities in the daily work of frontline professionals. Contributing to the sociological debate on priority setting and rationing, this study develops an analytical perspective attuned to the relational aspects of frontline work and the challenges related to the balancing of diverging ideas of good conduct. Further, focussing on an empirical field at the forefront of genomic medicine, this study brings the sociological debate on priority setting and rationing up to date with current developments in precision medicine.
Eosinophilic myocarditis from a forensic histopathological perspective
Authors: Gun Eylul , Bugra Aytul 
Published: January 2023

AbstractEosinophilic myocarditis (EM) is a rare and potentially fatal form of myocarditis characterized by infiltration of the myocardium with eosinophil leukocytes, often accompanied by eosinophilia. Although the exact underlying cause remains unknown, it has been shown to be associated with hypersensitivity reactions, immune‐mediated disorders, infections, or cancer. Due to the differences in symptomatology, it is often diagnosed by postmortem histopathological examination. We aimed to retrospectively examine the histopathological findings of rare cases of EM and to detect accompanying cardiac and other organ pathologies. The histopathological findings of the cases that underwent autopsies between 2012 and 2020 and were diagnosed with EM were assessed. Demographic features, symptoms, causes of death, macroscopical findings at autopsy, toxicologic and microbiological analysis results, accompanying cardiac pathologies, and histopathological findings in other organs were evaluated. Myocarditis was detected on histopathologic examination in 558 (1.1%) of 49,612 forensic autopsies. There were 12 (2.3%) EM cases. There were nine males and four females. The mean age was 42.3 (3–83) years. Heart weights ranged from 82 to 564 g. The most common finding on macroscopic examination was the mottled discoloration and scarring in the myocardium. Microscopic examination revealed perivascular and interstitial infiltration of eosinophils in all of the cases accompanied by myocyte necrosis in four of them. EM was reported as the cause of death in four cases. EM remains a challenging heart disease with its obscure etiopathogenesis and varying clinical presentation and a rare entity diagnosed by postmortem histopathological examination in sudden and unexpected deaths.
Colonialism Otherwise and the Poetics of Solidarity: A Methodological Intervention De‐b/ordering Kashmir
Authors: Dar Sadhvi , Masood Ayesha 
Published: January 2023

AbstractThis paper reflects deeply on possibilities for developing solidarity with Kashmiri freedom struggles by mobilising a memorialisation praxis informed by poetics. We coin the term “colonialism otherwise” to describe the particular instruments and effects of postcolonial colonialism as they appear in the intimate space of family narratives, memories, and feelings. Foregrounding the works of the Kashmiri poet, essayist, and filmmaker, Uzma Falak, we write our memorialisations to respond to the poet's demands to bear witness to Kashmiri people's abjection. Our memorialisation praxis is guided by the questions: how do we know Kashmir as a place, and relatedly, what are the political limitations of our articulated solidarity with the anti‐colonial struggle forazaadi?
New “drugs and targets” in the GWAS era of bipolar disorder
Authors: Qi Hao‐Xiang , Xiao Xiao , Li Tao , Li Ming 
Published: January 2023

AbstractObjectiveDue to the phenotypic heterogeneity and etiological complexity of bipolar disorder (BD), many patients do not respond well to the current medications, and developing novel effective treatment is necessary. Whether any BD genome‐wide association study (GWAS) risk genes were targets of existing drugs or novel drugs that can be repurposed in the clinical treatment of BD is a hot topic in the GWAS era of BD.MethodsA list of 425 protein‐coding BD risk genes was distilled through the BD GWAS, and 4479 protein‐coding druggable targets were retrieved from the druggable genome. The overlapped genes/targets were subjected to further analyses in DrugBank, Pharos, and DGIdb datasets in terms of their FDA status, mechanism of action and primary indication, to identify their potential for repurposing.ResultsWe identified 58 BD GWAS risk genes grouped as the druggable targets, and several genes were given higher priority. These BD risk genes were targets of antipsychotics, antidepressants, antiepileptics, calcium channel antagonists, as well as anxiolytics and analgesics, either existing clinically‐approved drugs for BD or the drugs than can be repurposed for treatment of BD in the future. Those genes were also likely relevant to BD pathophysiology, as many of them encode ion channel, ion transporter or neurotransmitter receptor, or the mice manipulating those genes are likely to mimic the phenotypes manifest in BD patients.ConclusionsThis study identifies several targets that may facilitate the discovery of novel treatments in BD, and implies the value of conducting GWAS into clinical translation.
Challenges and solutions to sustaining paediatric weight management programs in the United States
Authors: Christison Amy L. , Ariza Adolfo J. , Fernandez Cristina , Kumar Seema , Novick Marsha B. , Santos Melissa , Stratbucker William B. , Sweeney Brooke R. , Vidmar Alaina , Kirk Shelley 
Published: January 2023

SummaryPaediatric weight management (PWM) programs in the United States (US) face challenges in providing sustainable multidisciplinary care for patients. The aim of this study was to report PWM program approaches to sustaining program delivery. A survey of 39 PWM programs was administered to identify challenges and solutions to program sustainability. Common and useful strategies for optimizing reimbursement for services included the use of applicable reimbursable diagnostic codes and management, billing for assessments and non‐medical personnel services, and the use of hospital outpatient department clinic billing. Increasing clinical breadth and capacity was achieved by offering telemedicine and other services, such as psychotherapy, pharmacotherapy, and metabolic and bariatric surgery, as well as active management of schedules. Securing institutional and extramural funding was also reported. One of the positive changes during the pandemic was the fast adoption of telemedicine services. Although delivering sustainable evidence‐based multidisciplinary PWM under the current US payment models has its challenges, PWM programs implement practical operational strategies to support this work.
Optimal dose of rituximab in ABO‐incompatible kidney transplantation in patients with low anti‐A/B antibody titers: A single‐center retrospective cohort study
Authors: Okada Manabu , Narumi Shunji , Hasegawa Yuki , Futamura Kenta , Hiramitsu Takahisa , Ichimori Toshihiro , Goto Norihiko , Kobayashi Takaaki , Uchida Kazuharu , Takeda Asami , Watarai Yoshihiko 
Published: January 2023

AbstractBackgroundThe clinical outcomes of ABO‐incompatible (ABOi) kidney transplantation have improved with the introduction of desensitization therapy with rituximab. However, rituximab prevents not only antibody‐mediated rejection (AMR) but also increases the risk of adverse events, such as infection. For ABOi kidney transplantation in patients with low anti‐A/B antibody titers, we previously used a rituximab‐free desensitization protocol and then initiated a single dose of 100 mg rituximab in 2016. We retrospectively compared the outcomes of ABOi kidney transplantation in patients with low anti‐A/B antibody titers before and after the introduction of rituximab.MethodsABOi kidney transplantations (n = 142) in patients with low anti‐A/B antibody titers between 2007 and 2021 were included. Patients were divided into two groups (with and without rituximab) for desensitization. The primary outcomes were the incidence of acute AMR and infection.ResultsSixty‐six patients were desensitized without rituximab (rituximab‐free group), and 76 were pretreated with 100 mg rituximab (rituximab group) before transplantation. The incidence of acute AMR was significantly lower in the rituximab group than in the rituximab‐free group (.0% [0/76] vs. 7.6% [5/66], respectively; p = .047). Post‐transplantation anti‐A/B antibody titers were also lower in the rituximab group than in the rituximab‐free group. There was no significant difference in the incidence of adverse events, including infections, between the two groups.ConclusionIn ABOi kidney transplantation patients with low anti‐A/B antibody titers, the desensitization protocol with a single dose of 100 mg rituximab was effective in preventing acute AMR without increasing the risk of other adverse events.
Widespread habitat for Europe's largest herbivores, but poor connectivity limits recolonization
Authors: Bluhm Hendrik , Diserens Tom A. , Engleder Thomas , Heising Kaja , Heurich Marco , Janík Tomáš , Jirků Miloslav , Klich Daniel , König Hannes J. , Kowalczyk Rafał , Kuijper Dries , Maślanko Weronika , Michler Frank‐Uwe , Neumann Wiebke , Oeser Julian , Olech Wanda , Perzanowski Kajetan , Ratkiewicz Mirosław , Romportl Dušan , Šálek Martin , Kuemmerle Tobias 
Published: January 2023

AbstractAimSeveral large‐mammal species in Europe have recovered and recolonized parts of their historical ranges. Knowing where suitable habitat exists, and thus where range expansions are possible, is important for proactively promoting coexistence between people and large mammals in shared landscapes. We aimed to assess the opportunities and limitations for range expansions of Europe's two largest herbivores, the European bison (Bison bonasus) and moose (Alces alces).LocationCentral Europe.MethodsWe used large occurrence datasets from multiple populations and species distribution models to map environmentally suitable habitats for European bison and moose across Central Europe, and to assess human pressure inside the potential habitat. We then used circuit theory modeling to identify potential recolonization corridors.ResultsWe found widespread suitable habitats for both European bison (>120,000 km2) and moose (>244,000 km2), suggesting substantial potential for range expansions. However, much habitat was associated with high human pressure (37% and 43% for European bison and moose, respectively), particularly in the west of Central Europe. We identified a strong east–west gradient of decreasing connectivity, with major barriers likely limiting natural recolonization in many areas.Main conclusionsWe identify major potential for restoring large herbivores and their functional roles in Europe's landscapes. However, we also highlight considerable challenges for conservation planning and wildlife management, including areas where recolonization likely leads to human–wildlife conflict and where barriers to movement prevent natural range expansion. Conservation measures restoring broad‐scale connectivity are needed in order to allow European bison and moose to recolonize their historical ranges. Finally, our analyses and maps indicate suitable but isolated habitat patches that are unlikely to be colonized but are candidate locations for reintroductions to establish reservoir populations. More generally, our work emphasizes that transboundary cooperation is needed for restoring large herbivores and their ecological roles, and to foster coexistence with people in Europe's landscapes.
Antineurofascin IgG2‐associated paediatric autoimmune nodopathy
Authors: Harris Rachel E. , Atherton Mark , Naude Johann Te Water , Bird‐Lieberman Georgina A. , Ramdas Sithara , Fehmi Janev , Rinaldi Simon , Ong Min T. 
Published: January 2023

AbstractIn this case series of four paediatric patients, we present the first described cases of immunotherapy‐responsive autoimmune nodopathy with IgG2 antineurofascin antibodies. In three cases, the antineurofascin antibodies were predominantly of the IgG2 subclass, a novel finding in comparison to previously described adult cases where IgG4 and/or IgG1/3 have typically been described. One patient had low signal for IgG2 with predominant IgG1 and IgG4 antibodies, a pattern commonly seen in adult patients. Two patients had antibodies targeting all three neurofascin isoforms (155, 186, and 140), whereas antibodies in the sera from the third targeted only the nodal isoforms 186 and 140, and the fourth patient only neurofascin 155. The three patients with IgG2 predominant antibodies appear to be responsive to intravenous immunoglobulin (IVIG) to varying degrees thus far, whereas the patient with IgG1/4 antibodies had poor response to IVIG but good response to steroids. Although the full clinical significance of IgG2 predominant antineurofascin antibodies in the context of childhood polyneuropathy remains unclear, emerging evidence of serological‐phenotypic correlation may inform prognostication and therapeutic decision‐making, warranting further study into this area.What this paper adds

Paediatric immunotherapy‐responsive nodopathies were associated with antineurofascin antibodies predominantly of the IgG2 subclass in 3 out of 4 patients.
Identification of antibodies and understanding their phenotypic relevance could predict response to treatment and guide therapeutic decision‐making in children.
Push‐pull and kill strategy for Diaphorina citri control in citrus orchards
Authors: Eduardo Wellington Ivo , Silva Ana Caroline , Volpe Haroldo Xavier Linhares , Alquézar Berta , Peña Leandro , Miranda Marcelo Pedreira 
Published: January 2023

AbstractThe development of sustainable methods to control Diaphorina citri Kuwayama (Hemiptera: Liviidae) is crucial to improve management of huanglongbing (HLB), the most important citrus disease worldwide. In a flushing Citrus × sinensis L. Osbeck (Rutaceae) orchard, this study assessed the combined effects of insecticide‐treated Bergera koenigii L. (Rutaceae) trees in the orchard border, as a lethal trap crop, and the application of processed kaolin to the citrus crop, as a repellent (push‐pull and kill strategy), in reducing D. citri infestation and dispersal. Additionally, the volatile organic compound (VOC) emission profile and attractiveness of B. koenigii shoots were investigated in indoor experiments. The push‐pull and kill strategy reduced the number of D. citri adults on citrus trees by 95, 84, and 63% compared to the untreated control, trap crop only, and kaolin only treatments, respectively. These high reductions can be attributed to the combination of attractive stimuli (VOCs) and repellent stimuli by the trap crop and kaolin, respectively. The number of psyllids observed on citrus trees subjected to treatments with trap crop and kaolin separately was 69 and 86% lower than on untreated control trees, respectively. In addition, all treatments reduced and delayed D. citri dispersal inside the orchard, especially the push‐pull and kill strategy. In olfactometric assays, D. citri females showed a significant preference for B. koenigii odors over C. × sinensis cv. ‘Valencia’ flush odors, likely related with the different VOC emission profiles of the two plants. This study shows the effectiveness of push‐pull and kill as a new management strategy to control D. citri and consequently HLB.