bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feeding Comfort: The Role of Humor in Online Food Complaints
Authors: Armstrong Christine , Kulczynski Alicia , Hook Margurite 
Published: January 2025

ABSTRACTThis research examines the impact of tone mirroring in organizational responses to food complaints on social media. Drawing on cognitive appraisal theory, two experiments explore how mirroring—matching the tone of the complaint, whether humorous or non‐humorous—influences consumer emotions and intentions. The findings show that humorous responses to humorous complaints and non‐humorous responses to non‐humorous complaints significantly enhance psychological comfort among virtual observers (VPOs). This psychological comfort, in turn, increases purchase intentions and decreases the likelihood of negative word‐of‐mouth. However, in high‐severity service failures, humorous mirroring is ineffective, as the severity of the service failure moderates the indirect effect of mirroring on consumer outcomes via psychological comfort. By highlighting mirroring—rather than humor alone—as a critical mechanism shaped by the severity of the service failure, this study extends our understanding of the role of humor in complaint management. The results offer both theoretical contributions and practical guidance for organizations managing food complaints on social media.
Plackett‐Burman Design Combined With Response Surface Methodology to Recover Polysaccharides With Cardiovascular Protective Potential From Waste Zizania Latifolia Bract
Authors: Zheng Lixue , Chen Qianfeng , Zhou Xin , Yin Run , Yang Jingchun , Hu Zhenbiao , Shen Yingchao , Zhang Yang 
Published: January 2025

ABSTRACTZizania latifolia is the second aquatic vegetable in China. The circular valorization of its waste bracts remains an ongoing concern. In this work, the cellulase‐microwave‐assisted extraction (CMAE) of polysaccharides from waste Z. latifolia bracts (PWZLBs) was explored. Seven parameters were selected via a single‐factor test, of which three significant parameters were screened out using the Plackett‐Burman design, followed by response surface methodology optimization. The optimal CMAE for PWZLBs were: cellulase addition of 0.5%, microwave time of 7 min, and microwave power of 425 W, resulting in a yield of 0.82 ± 0.08%. Four polysaccharide fractions (PWZLBs‐1 ∼ 4) were isolated from PWZLBs, of which PWZLBs‐1 accounted for a major proportion and exerted higher scavenging capacities on diphenyl picrylhydrazyl and hydroxyl radicals. More importantly, PWZLBs‐1 elicited anticoagulation via prolonging thrombin time and prothrombin time, exhibiting potential for cardiovascular protection. Various characterizations confirmed that PWZLBs‐1 is a heteropolysaccharide containing uronic acids and sulfates, with galactose (34.3%) as the predominant monosaccharide, and has a molecular weight of 8061 kDa. This work provides clues for the circular valorization of waste Z. latifolia bracts and offers potential opportunities for the development of new cardiovascular protective drugs.
Microwave‐Assisted Synthesis of Bis‐1,2,3‐Triazole‐Based Benzophenones, In Vitro Antimicrobial Activity, and Molecular Docking Studies
Authors: Dharavath Ravinder , Meena Ravila , Ranjan Amit , Thumma Vishnu 
Published: January 2025

ABSTRACTIn this work, we have adopted an easy route to synthesize bis‐1,2,3‐triazole‐based benzophenone compounds via a 1,3‐dipolar cycloaddition reaction (Click chemistry). All the target compounds achieved better yields through the microwave‐assisted method than the conventional method. Target compound structures were confirmed on the basis of the IR, 1H NMR, 13C NMR, and HR mass analysis. Additionally, we have carried out in vitro antibacterial and antifungal activities with ciprofloxacin and fluconazole standard drugs, respectively. Compounds 5b, 5f, 5i, 5k, and 5n were antibacterial, whereas 5a, 5e, 5g, 5i, and 5k showed promising antifungal activity with respect to standard drugs. Further, a molecular docking study performed against DNA gyrase and lanosterol 14‐alpha demethylase envisioned promising binding interactions with a good docking score.
Persistent Aggressive Behaviour From Childhood to Adolescence: The Influence of Environmental Tobacco Exposure and the Protective Role of Fish Consumption
Authors: Liu Jianghong , Yang Yi , Shi Haoer , Wong Keri Ka‐Yee , Raine Adrian 
Published: January 2025

ABSTRACTBackgroundUnderstanding changes in aggressive behaviour throughout child development is crucial for identifying effective intervention strategies. This study investigates children's aggressive behaviour in a longitudinal cohort and explores the role of environmental tobacco exposure and fish consumption as potential risk and protective factors, respectively, for persistent aggression in children.MethodsThis study involved 452 children from the Chinese Jintan Cohort. Aggressive behaviour was assessed at ages 6 and 12 years using the child behaviour checklist (CBCL) and the Reactive–Proactive Aggression Questionnaire (RPQ), respectively. Information on lifestyle habits and living environment, including parental smoking, was collected via questionnaires. Linear regression was employed to investigate the association between childhood and adolescence aggressive behaviour with relevant covariates adjusted. Subsequently, we conducted interaction analyses to explore the moderating effects of parent smoking and fish consumption on the association.ResultsWe identified no significant association between childhood and adolescent aggression in the entire sample. Interaction analysis revealed environmental tobacco exposure as a moderator for the association. Specifically, persistent reactive and total aggression across development was only observed among those with environmental tobacco exposure (reactive: β = 0.549, p = 0.020; total: β = 0.654, p = 0.035). Furthermore, within the parent smoking subgroup, freshwater fish consumption at the age of 12 showed a marginally significant interaction with childhood aggression (reactive: p = 0.061; total: p = 0.095). A significant longitudinal association for aggression was found only among those consuming fish less frequently at the age of 12 years (reactive: β = 0.927, p = 0.002; total: β = 1.082, p = 0.006).ConclusionOur findings suggest exposure to environmental tobacco as a contributing factor to the lasting presence of aggressive behaviour during children's development, whereas freshwater fish consumption shows potential protective effects.
The Positive Effect of Psychotherapy in the Treatment of an Erosive Oral and Dermal Lichen Planus Case
Authors: Noori Zana Fuad , Mahmood Mohammed Khalid , Raof Pinar Yaseen , Kurda Handren Ameer , Qadir Balen Hamid , Abdulrahman Didar Anwar , Abdulghafor Mohammed Aso , Fatih Mohammed Taib , Hama Noori Basoz Khalid 
Published: January 2025

ABSTRACTLichen planus (LP) is an autoimmune disease that may affect the oral cavity and the skin, and it has the potential to change to malignancy. In this paper we report a LP case in a 42‐year‐old male patient in which anxiety and depression were apparently the only possible risk factors of LP. Due to this apparent comorbidity and the risk of not responding well to conventional medication (topical and systemic corticosteroids) or the risk of relapse in the case of ongoing stress, we decided to integrate psychotherapy (without psychotropic drugs) as an adjunct into the management strategy. Psychotherapy sessions, reassuring the patient and stress alleviation, proved to be a very useful alongside the standard corticosteroid medication.
Pincer–Ruthenium Catalyzed Selective α‐Alkylation of Nitriles
Authors: Vikas  , Pasha Farhan Ahmad , Kumar Akshai 
Published: January 2025

AbstractThe catalytic α‐alkylation of benzyl nitriles with benzyl alcohols has been investigated with NNN pincer–ruthenium (Ru) complexes based on bis(imino)pyridine and 2,6‐bis(benzimidazole‐2‐yl)pyridine ligands. The complex [Cy2NNN(RuCl2(PPh3)] was found to be the most efficient in comparison to other considered catalysts, leading to a 99% yield of α‐alkylated nitrile with 100% selectivity in the presence of 3 mol% KOtBu in 1 mL of toluene at 140 °C within 2 h of reaction. While the release of PPh3 appears to be pivotal, mercury drop experiments point to the well‐defined molecular nature of the pincer–Ru catalyst. The reaction demonstrates first‐order dependence of rate on the concentration of [Cy2NNN(RuCl2(PPh3)], KOtBu, benzyl alcohol, and benzyl nitrile. DFT calculations indicate that the formation of α‐alkylated nitrile via the alcoholysis path with a barrier of 28.7 kcal/mol is the rate‐determining step (RDS) owing to equilibrium‐driven reasons despite the hydrogenolysis path being kinetically comparable (ΔG140‡ = 29.0 kcal/mol). These barriers are in good agreement with the experimentally determined barrier of 29.6 kcal/mol.
Artificial and Algorithmic Screening of Infrared Spectral Feature Bands of Gastrodia elata to Achieve Rapid Identification of Its Species
Authors: Liu Shuai , Liu Honggao , Li Jieqing , Wang Yuanzhong 
Published: January 2025

ABSTRACTGastrodia elata is a traditional Chinese medicine with medicinal and edible values. In this paper, two kinds of datasets were acquired: partial spectra (artificially obtained peak segment spectra) and full spectra (4000–400 cm−1). Competitive adaptive reweighted sampling algorithm (CARS) and successive projection algorithm (SPA) were utilized to extract the characteristic variables of the two datasets, and Partial Least Squares Discriminant Analysis (PLS‐DA) models, Support Vector Machines (SVM) models, Random Forests (RF) models, and Residual convolutional neural networks (ResNet) were established. It was found that among the PLS‐DA models whole‐MSC‐CARS‐PLS‐DA was optimal, with a Root Mean Square Error of Prediction (RMSEP) of 0.0658; among the SVM models Partial‐Standard Normal Variable (SNV‐SPA‐SVM was the best, with a kernel parameter of 0.1768 and the lowest number of support vectors; among the RF models Partial‐SNV‐RF is optimal, but not as effective as the first two models. The loss value of the ResNet model built based on effective information is 0.001, and the model building time is short and directly uses the original data. Therefore, the ResNet model based on feature bands is the most suitable for practical application compared with other models.
Synthesis of α,β‐Unsaturated Carbonyl Compounds via Cu/TEMPO/O2 Aerobic Catalytic System
Authors: Wang Yao , Du Zhi‐Hong , Bo Chunbo , Li Min , Chen Fei , Liu Ning 
Published: January 2025

AbstractAn N,N,N‐type Cu(II) complex‐catalyzed desaturation method for converting alcohols, ketones, lactones, and lactams to their α,β‐unsaturated carbonyl compounds is reported. The dehydrogenation reaction can be conducted with a green terminal oxidant O2 without requiring strong acid/base or stoichiometric oxidants. The Cu(II) complex/TEMPO/O2 system uses a non‐noble catalyst, and a green terminal oxidant as well as demonstrates high activity and functional group tolerance. Notably, H2O is the byproduct produced and overoxidation is not observed during the reaction process. The proposed mechanism was investigated via high‐resolution mass spectrometry (HRMS), in situ FT‐IR spectrometry, and GC analysis, and the formation of intermediates of α,β‐unsaturated carbonyl compounds from the aerobic dehydrogenation of α,β‐saturated counterparts was observed.
A Non‐Volatile Pro‐Dicamba Herbicide Inspired by Meclofenoxate
Authors: Haywood Joel , Breese Karen J. , Jordi Muria‐Gonzalez M. , Bernath‐Levin Kalia , Waters Mark , Stubbs Keith A. , Mylne Joshua S. 
Published: January 2025

AbstractDicamba is a popular herbicide with rising use but is also notorious for volatility drift. Inspired by meclofenoxate, which we show to be highly herbicidal, we developed a derivative of dicamba with an ester‐bond to 2‐dimethylaminoethanol. It remained herbicidal but is non‐volatile, entering plants intact and hydrolyzing inside leaves to dicamba and 2‐dimethylaminoethanol. This pro‐dicamba is compatible with the relatively novel dicamba monooxygenase tolerance technology, suggesting pro‐dicamba might be a suitable, non‐volatile replacement for dicamba.
Intermolecular 1,2‐Difunctionalization of Nitriles via Redox Gold Catalysis: Synthesis of Benzoxazoles and Benzimidazoles
Authors: Xu Chengzhi , Xu Zhenyan , Chen Yifeng , Chen Ming , Liu Yuanhong 
Published: January 2025

AbstractThe unprecedent gold‐catalyzed intermolecular 1,2‐difunctionalization of nitriles with o‐iodophenols or o‐iodoanilines via Au(I)/Au(III) redox catalysis has been developed, providing an expedient route to the synthesis of benzoxazoles or benzimidazoles with broad substrate scope and high functional compatibility. Mechanistic investigation reveals that the Au(III)‐Ar species generated via oxidative addition of o‐iodophenol to MeDalphosAu+, serves as a key intermediate. Particularly, this annulation is initiated by oxidative addition, rather than the nucleophilic attack of the phenol moiety in o‐iodophenol towards the nitrile. The method was also applied to the synthesis of poly aza‐heterocycles via a cascade Au(I)/Au(III) and Au(I) catalysis relay.
Impact of Standardized Heart Failure Management Center Construction on the Management of Patients With Chronic Heart Failure
Authors: Guo Xiaoxia , Jing Lele , Zhai Changlin , Shen Liang , Hu Huilin 
Published: January 2025

ABSTRACTBackgroundHeart failure is extremely harmful to human health and social economics. The purpose of standardized heart failure management center (SHFMC) is to correct the non‐standardization of heart failure treatment.HypothesisSHFMC has a positive impact on the management and prognosis of patients with chronic heart failure (CHF).MethodsThe SHFMC database of Jiaxing First Hospital was retrospectively analyzed. Two hundred sixty‐three patients with CHF who were hospitalized in the cardiovascular medicine department of Jiaxing First Hospital in Zhejiang Province from January 2020 to December 2020 were identified as study subjects. The SHFMC opening day, July 1, 2020, was used as the dividing line around which the patients were divided into Group A (before the completion of SHFMC, n = 137) and Group B (after, n = 126). The baseline data, treatment standardization, long‐term efficacy, 1‐year all‐cause mortality, and readmission rate of the two groups were compared.ResultsThe use of angiotensin receptor enkephalinase inhibitors (ARNIs), β‐blockers (β‐Bs), and sodium‐glucose cotransport protein 2 inhibitors (SGLT2is) increased significantly, and the long‐term outcome, readmission rate, and 1‐year all‐cause mortality of patients improved in group B.ConclusionsThe construction of SHFMC has been associated with consistent improvements in the standardization of CHF treatment, long‐term patient outcomes, 1‐year cumulative survival rates, and readmission rates.
Detecting Rising Wildfire Risks for South East England
Authors: Thompson Vikki , Mitchell Dann , Melia Nathanael , Bloomfield Hannah , Dunstone Nick , Kay Gillian 
Published: January 2025

ABSTRACTIn July 2022 southeast England experienced a record breaking heatwave and unprecedented wildfires in urban areas. We investigate fire weather trends since 1960 in southeast England using a large ensemble of initialised climate models. Record smashing temperatures coincided with widespread fires in London, and we find that while wildfire risk was high, it was not record breaking. We show that between the 1960s and 2010s annual maximum daily fire weather has increased. The proportion of summertime days with high and very high fire risk has increased—while medium and low risk days have become less common. These findings show the need to mitigate against the increasing risk of wildfire caused by climate change.
Predictive Methods and Probabilistic Mapping of Subcortical Brain Components in Fossil Carnivora
Authors: Baer Emily , Nguyen Phuoc D. , Lilly Stefan , Song Jiyoon , Yee Mathew , Matz Olivia , Sahasrabudhe Rachna , Hall Douglas R. , La Susan , Merritt Brandon J. , Mahesh Pallavi , Eliacin Christelle , Bitterman Kathleen , Oddes Demi , Bertelsen Mads F. , Tang Cheuk Y. , Cook Peter F. , Mars Rogier B. , Hof Patrick R. , Dunn Rachel , Manger Paul R. , Sherwood Chet C. , Spocter Muhammad A. 
Published: January 2025

ABSTRACTPaleoneurology reconstructs the evolutionary history of nervous systems through direct observations from the fossil record and comparative data from extant species. Although this approach can provide direct evidence of phylogenetic links among species, it is constrained by the availability and quality of data that can be gleaned from the fossil record. Here, we sought to translate brain component relationships in a sample of extant Carnivora to make inferences about brain structure in fossil species. Using high resolution magnetic resonance imaging on extant canids and felids and 3D laser scanning on fossil Carnivora, spanning some 40 million years of evolution, we derived measurements for select brain components. From these primary data, predictive equations of cortical (gray matter mass, cortical thickness, and gyrification index) and subcortical structures (caudate nucleus, putamen, and external globus pallidus mass) were used to derive estimates for select fossil Carnivora. We found that regression equations based on both extant and simulation samples provided moderate to high predictability of subcortical masses for fossil Carnivora. We also found that using exploratory probabilistic mapping of subcortical structures in extant Carnivora, a reasonable prediction could be made of the 3D subcortical morphospace of fossil endocasts. These results identify allometric departures and establish adult species ranges in brain component size for fossil species. The integrative approach taken in this study may serve as a model to promote further dialog between neurobiologists working on extant Carnivora models and paleoneurologists describing the nervous system of fossils from this understudied group of mammals.
Deciphering the Evolution of Current Distribution in Hybrid Silver Vanadium Oxide / Carbon Monofluoride Cathodes within Lithium Primary Batteries
Authors: Arnot David J. , Vila Mallory N. , Hill Ryan C. , Kingan Arun , Zhong Zhong , Vo Nghia T. , Drakopoulos Michael , Takeuchi Esther S. , Marschilok Amy C. , Takeuchi Kenneth J. 
Published: January 2025

AbstractFor batteries to function effectively all active material must be accessible requiring both electron and ion transport to each particle. A common approach to generating the needed conductive network is the addition of carbon to create a composite electrode. An alternative approach is the electrochemically induced formation of conductive reaction products where the electrochemically generated materials are in intimate contact with the active material contributing to effective connection of each active particle. This study probes silver vanadium oxide (Ag2V4O11, SVO), carbon monofluoride (CFx), and hybrid SVO/CFx electrodes in lithium batteries. Ex situ XRD identifies Ag0 as a reduction product from SVO and LiF from CFx that can be followed as a function of depth‐of‐discharge (DOD). Spatially‐resolved operando energy dispersive x‐ray diffraction reveals that the presence of SVO alleviates reaction heterogeneity in the electrodes which are electron transfer limited in the absence of sufficient Ag0. Synchrotron X‐ray tomography on discharged cathodes reveals the distribution of silver particles where the particles are more closely spaced near the current collector indicating multiple nucleation sites for their formation. Finally, operando isothermal microcalorimetry is used to determine the heat dissipation of the parent and hybrid battery types. Using material enthalpy potentials, we determine the current distribution between the two active materials for the discharging hybrid cathode adding further insight to the diffraction analysis. Taken together, these results provide a comprehensive understanding of hybrid SVO/CFx cathodes and give guidance on optimal compositions that balance power and energy density considerations.
A Simple Protocol for Visualization of RNA–Protein Complexes by Atomic Force Microscopy
Authors: Tripepi Andrea , Shakoor Huma , Klapetek Petr 
Published: January 2025

AbstractAtomic force microscopy (AFM) has recently received increasing interest in molecular biology. This technique allows quick and reliable detection of biomolecules. However, studying RNA–protein complexes using AFM poses significant challenges. Here, we describe a simple and reliable method to visualize positively charged proteins bound to RNA that does not require metallic cations. This method allowed us to effectively detect and visualize Staufen–RNA complexes by height or logarithmic stiffness. The study of the mechanical properties is particularly important in the case of protein‐coated RNA complexes, where RNA cannot be detected by height channel. In any case, it is necessary to compare AFM data with the data derived from other techniques like nuclear magnetic resonance, X‐ray crystallography, cryogenic electron microscopy, and small‐angle X‐ray scattering. © 2025 The Author(s). Current Protocols published by Wiley Periodicals LLC.Basic Protocol: Preparation and visualization of RNA–protein complex
Aligning Investment With Impact: Exploring Social Impact Bonds in Emerging Markets for Sustainable Development
Authors: Velez‐Valencia Cristina , Herrera‐Cano Carolina , Gonzalez‐Perez Maria Alejandra , Alvarez Pilar , Vergara Garavito Judith 
Published: January 2025

ABSTRACTThis article explores investor motivations and the contribution to sustainable development goals of social impact bonds (SIBs) in emerging markets. Through qualitative analysis of in‐depth stakeholder interviews, we identified that SIB investors are primarily driven by organisational learning, social impact generation and strategic alignment with core business objectives rather than financial returns. Our findings reveal that SIBs offer a pathway for achieving corporate social responsibility (CSR) and environmental, social and governance (ESG) objectives by blending private investment with public goals. Drawing on signalling theory, we exhibit how SIBs serve as credible signals of institutional commitment to sustainable development. The study contributes to the literature by identifying the role of SIBs in fostering public–private partnerships via signalling and investors' approaches to environmental and social challenges in emerging economies. This research expands our understanding of SIBs' potential within the CSR and ESG framework and proposes practical implications for businesses seeking to enhance their sustainability impact.