bluuebunny/crossref_metadata_2025_split huggingface dataset:
Results of Surgical Treatment of Elderly and Senile Patients With Acute Ischemia of the Lower Extremities of Embologenic Origin
Authors: Mikhailov I. P. , Arustamyan V. A. , Rey S. I. , Mikerova M. S. 
Published: April 2023

BACKGROUND Today, one of the urgent problems of emergency vascular surgery is the high mortality rate in acute ischemia of the lower extremities in elderly and senile patients.AIM OF STUDY To evaluate the incidence of complications in elderly and senile patients with acute ischemia of the lower extremities of embologenic origin.MATERIAL AND METHODS As an object of study, three groups of elderly and senile patients admitted with a clinical picture of acute ischemia of the lower extremities were studied. Group I — patients who underwent reconstructive interventions in the scope of the so-called proximal reconstruction; group II — patients who, for the purpose of complete revascularization, underwent extended reconstructive interventions using an additional surgical approach; group III — patients who underwent a “classic” embolectomy.RESULTS Good results were statistically significantly more common in group II. Satisfactory and poor results were observed in group III. Amputations were statistically significantly more common in group III. In 69.6% of cases, the use of plasmapheresis and infusion therapy prevented the development of acute renal injury.CONCLUSION Performing extended arterial reconstructions, including using an additional surgical approach, makes it possible to more fully restore the main blood flow in the ischemic limb and thereby completely restore the main blood flow in the ischemic limb and reduce the degree of ischemia, as well as reduce the severity of the manifestation and course of the post-ischemic syndrome.
Features of the Immune Response in COVID-19
Authors: Inyutkina A. A. , Nikulina V. P. , Godkov M. A. 
Published: April 2023

BACKGROUND This review is devoted to the analysis of the features of the immune response in COVID-19. The review indicates the clinical manifestations of COVID-19, modern data on the immunopathogenesis of the disease and its complications are considered.Aim of STUDY To clarify some pathogenetic mechanisms of the immune response in COVID-19, which can help in creating an algorithm for examining patients for early prognosis and prevention of severe course and complications of the disease.MATERIAL AND METHODS To achieve this goal, the results of domestic and foreign scientific studies on the pathogenesis, diagnosis and treatment of COVID-19 were analyzed. The literature search was carried out in electronic search engines Scopus and PubMed. For the analysis, scientific articles published in the period from 2019 to 2021 were selected; 88% of analyzed works are not older than 5 years.CONCLUSION The late production of type I IFN, an increase in the level of pro-inflammatory monocytes, a decrease in the expression of HLA-DR on monocytes, violation of the presentation of the virus and the formation of specific lymphocytes, the death of T-lymphocytes and profound immunosuppression are of greatest importance for the development of a severe form of COVID-19.
The Choice of Tactics for Surgical Treatment of Acute De Bakey Type I Aortic Dissection in a Multidisciplinary Surgical Hospital
Authors: Redkoborody A. V. , Selyaev V. S. , Rubtsov N. V. , Kokov L. S. , Muslimov R. Sh. , Popova I. E. , Torshkhoyev K. M. , Khutsishvili L. G. 
Published: April 2023

BACKGROUND Acute proximal aortic dissection (Stanford type A) remains the most common fatal pathology of the thoracic aorta. Despite the improvement of surgical technologies, hospital mortality after emergency surgical interventions is 17–25%, in complicated cases it can reach 80–90%.AIM OF STUDY Description of the perioperative treatment tactics adopted at the N.V. Sklifosovsky Research Institute for Emergency Medicine as well as the evolution of approaches that make it possible to obtain satisfactory hospital and long-term results in the treatment of aortic dissection.MATERIAL AND METHODS the study included 278 patients operated on from 2015 to 2021 in the acute stage of aortic dissection (less than 48 hours from the moment of manifestation of the disease). The operated patients were divided into two groups, depending on the presence of complicated forms: group A, 102 patients with uncomplicated course of the disease; group B, 176 patients with complicated course of the disease. Additionally, patients were divided depending on the level of distal reconstruction performed: group I, 83 patients, surgery was limited to prosthetics of the ascending aorta, without removing the clamp; group II, 137 patients who underwent hemi-arch surgery; group III, 58 patients, with distal reconstruction involving the aortic arch.RESULTS Total hospital mortality was 28.1%: 25.3% in group I, 29.1% in group II, 29.3% in group III. In the group of uncomplicated dissection, postoperative mortality was 18.6%, while in the group of complicated dissection it was 33.5%.CONCLUSION An integrated multidisciplinary approach with the formation of an “aortic team”, an individual approach to surgery, depending on the anatomy of the dissection and the clinical status of the patient, will improve the results of the treatment of acute aortic dissection, as the most severe and multiple organ pathology of the aorta.FINDING 1. Hospital mortality of complicated forms of dissection remains significantly higher — 33.5% versus 18.5% of uncomplicated course. 2. The most optimal method of distal reconstruction in patients with the peracute stage of dissection is an open anastomosis with the aorta using the “hemi-arch” technique. 3. If it is necessary to extend the surgical intervention on the aortic arch, a distal anastomosis in areas 0, 1, 2 with the possibility of a subsequent endovascular stage is the priority.
PEMERIKSAAN GOLONGAN DARAH PADA IBU HAMIL SEBAGAI UPAYA SIAGA DONOR DARAH DI KELAS IBU HAMIL MITRA MAYA KELURAHAN PATANGPULUHAN, KECAMATAN WIROBRAJAN
Authors: Astuti Yuli , Artini Dyah , Danarsih Dwi Eni 
Published: April 2023

ABSTRAKLatar Belakang pengabdian kepada masyarakat ini bertema “Pemeriksaan Golongan Darah pada Ibu Hamil Sebagai Upaya Siaga Donor Darah”. Pengabdian masyarakat ini berfokus pada ibu hamil sebagai salah satu upaya untuk ,meningkatkan Desa Siaga Donor Darah di Kelas Ibu Hamil Mitra Maya, Kelurahan Patangpuluhan, Kecamatan Wirobrajan.Tujuan dari pengabdian kepada masyarakat ini adalah untuk melakukan pemeriksaan golongan darah pada ibu hamil di Kelas Ibu Hamil Mitra Maya, Kelurahan Patangpuluhan, Kecamatan Wirobrajan.Metode pelaksanaan kegiatan ini direncanakan dalam tahapan yaitu : tahapan persiapan, tahap pelaksanaan dan tahap evaluasi. Tahapan persiapan meliputi pengurusan ijin, studi pendahuluan dengan observasi lapangan, pengumpulan bahan dan persiapan alat dan bahan pada saat kegiatan serta koordinasi dengan pihak terkait. Tahapan pelaksanaan kegiatan adalah melakukan pemeriksaan golongan pada calon pendonor darah di Kelas Ibu Hamil Mitra Maya, Kelurahan Patangpuluhan, Kecamatan Wirobrajan. Pada tahap evaluasi terdiri penyusunan laporan pertanggungjawaban kegiatan.Hasil yaitu 40% adalah golongan darah B, sebesar 28% golongan darah O, 20% golongan darah A, dan sebesar 12% golongan darah AB. Golongan darah rhesus 100% peserta golongan darah rhesus positif.Kesimpulan dari pengabdian ini adalah didapatkan golongan darah ibu hamil dan pendonor mayoritas adalah O dan rhesus positif.
UPAYA PENINGKATAN PENGETAHUAN PENYANDANG DIABETES MELITUS PADA MASA PANDEMI COVID-19 DI RS AMC CILEUNYI
Authors: Achadiyani Achadiyani 
Published: April 2023

Prevalensi diabetes yang tinggi di Indonesia menjadikannya komorbiditas yang sangat berpengaruh pada pasien dengan COVID-19. Orang tua dan orang-orang pada segala umur yang memiliki kondisi penyakit penyerta seperti diabetes, menunjukan prognosis yang buruk. Pasien diabetes memiliki peningkatan secara tingkat komorbiditas dan mortalitas yang berhubungan dengan manajemen rawat inap dan ICU. Program Pengabdian Kepada Masyarakat ini berupaya untuk meningkatkan pengetahuan penyandang diabetes melitus pada masa pandemi COVID-19. Kegiatan dilakukan pada pengunjung Rumah Sakit AMC, Cileunyi, Jawa Barat. Melalui hasil pre-test dan post-test yang dilakukan pada pengunjung Rumah Sakit AMC pada saat kegiatan berlangsung, dari total 10 poin, peningkatan hanya terjadi sebesar 1.9% dari rerata 6.26 poin menjadi 6.38. Temuan ini menunjukkan pengunjung Rumah Sakit AMC masih tidak acuh untuk meningkatkan pengetahuan penyakit diabetes melitus pada masa pandemi COVID-19 sehingga diperlukannya penyuluhan yang lebih repetitif dan personal sehingga pengunjung Rumah Sakit AMC dapat memahami pentingnya mengetahui diabetes melitus dan upaya modifikasi faktor risiko penyakit diabetes melitus pada masa pandemi COVID-19.
LITERASI KITAB TA'LIM MUTA'ALLIM PADA SMP IT AL-AMANAH KABUPATEN BANDUNG
Authors: NUGRAHA TUBAGUS CHAERU 
Published: April 2023

Tema pengabdian pada masyarakat ini adalah Pendampingan Literasi Kitab Ta'lim Muta'llim Pada SMP IT Al-Amanah di desa Cinunuk, Cileunyi, Kab. Bandung. Tujuan PPM ini adalah para siswa terpilih memahami dan mampu mengamalkan nilai-nilai Islam dalam adab menuntut ilmu yang terdapat pada kita Ta'lim Muta'llim. Adapun metode yang ditempuh untuk mewujudkan tujuan tersebut ada tiga tahap. Pertama, tahap persiapan berupa survei ke tempat sasaran dan memperoleh izin dari para tokoh dan pihak terkait dalam kegiatan PPM ini. Kedua, tahap pelaksanaan, melakukan pendampingan di SMP IT Al-Amanah desa Cinunuk, Cileunyi, Kab. Bandung. Adapun materi yang disampaikan adalah (1) adab dalam menuntut ilmu; (2) game edukasi nilai-nilai anti korupsi, dan (3) game membangkitan semangat belajar sungguh-sunggu. Ketiga, tahap evaluasi, monitoring dan pelaporan.
PENGUATAN PERAN WARGA MASYARAKAT DALAM MITIGASI DAN ADAPTASI MENGHADAPI MASA PANDEMI COVID-19
Authors: Intan Tania , Handayani Vincentia Tri , Ismail Nany 
Published: April 2023

Kegiatan Pengabdian Kepada Masyarakat ini dilaksanakan terintegrasi dengan Kuliah Kerja Nyata Integratif Virtual 2021 yang diselenggarakan pada bulan Januari dan Februari 2021. Seluruh kegiatan dengan tema “Penguatan Peran Warga Masyarakat dalam Mitigasi dan Adaptasi Menghadapi Masa Pandemi Covid-19” dilakukan secara daring, mulai dari tahap persiapan, pelaksanaan, evaluasi, hingga pelaporan. Tim pelaksana terdiri dari tiga orang dosen, dengan salah satunya sebagai DPL (Dosen Pembimbing Lapangan) dan dibantu oleh dua puluh orang mahasiswa yang berasal dari program studi berbeda di Universitas Padjadjaran. Masing-masing mahasiswa mendampingi dua subjek KKN yang berasal dari warga sekitar tempat tinggal masing-masing atau subjek lain yang dapat dijangkau secara daring. Dengan demikian, ada empat puluh subjek KKN sebagai mitra yang menjadi sasaran dari program-program yang dilaksanakan. Tema “Penguatan Peran Warga Masyarakat dalam Mitigasi dan Adaptasi Menghadapi Masa Pandemi Covid-19” dipilih karena sangat relevan dengan kondisi dan permasalahan yang dialami seluruh lapisan masyarakat saat ini. Tim PPM dan mahasiswa bekerja sama menggarap empat subtema yaitu: pendidikan, kesehatan dan lingkungan, ekonomi dan kewirausahaan, serta sosial dan budaya yang diturunkan ke dalam sejumlah program sosialisasi, edukasi, dan pembuatan poster serta video. Implikasi dari kegiatan ini adalah adanya perubahan-perubahan berupa peningkatan dari segi pengetahuan, sikap, dan keterampilan para subjek dalam menghadapi pandemi Covid-19.
Key quality control aspects about cannabinoid-rich hemp products that a veterinarian needs to know: a practitioner’s guide
Authors: Henion Jack , Evans Stacey , Wakshlag Joseph J. 
Published: April 2023

Abstract
There is considerable confusion in the veterinary profession surrounding the rise in hemp cannabidiol-based animal products and what veterinarians should know before discussing these products with clients. There is emerging evidence for the potential use in case management across many veterinary indications; however, the cannabinoid concentrations and whether these are isolated cannabinoids or whole hemp extracts is difficult to elucidate, even from the published papers. Much like any extract from a plant, there are multiple considerations including quality control, pharmacokinetics in the intended species, microbiological and chemical contamination, and product consistency—all aspects that should be considered before a conversation can begin with a client. The aim of this review is to help practitioners make informed decisions and better facilitate discussions with clients for companion animals kept as pets. This review will not address food animal issues, as established withholding times have yet to be fully researched.
Continuous surveillance and viral discovery in animals and humans are a core component of a one-health approach to address recent viral reverse zoonoses
Authors: Kibenge Frederick S. B. 
Published: April 2023

Abstract
Contemporary human and animal viruses have a broad or narrow host range—those with a broad host range are potentially transmitted from animals to humans (ie, zoonosis) or humans to animals (ie, reverse zoonosis). This Currents in One Health article reviews the recent reverse zoonoses involving Coronaviridae, Poxviridae, arboviruses, and, for nonhuman primate species, the human respiratory viruses. The prevention and control of reverse zoonoses are also reviewed. Coronaviruses continue to emerge as new zoonotic agents, including a canine coronavirus, CCoV-HuPn-2018, circulating in people at low levels, and a pangolin coronavirus, MjHKU4r-CoV-1, circulating in Malayan pangolins. Moreover, the risk for SARS-CoV-2 variants to mutate in animal reservoirs and reinfect humans is ongoing. In the case of mpox, the risk of reverse zoonosis is low and there are vaccines for use in humans at risk. The situation with arboviruses is as varied as the number of human arboviruses, and only yellow fever virus and dengue virus have licensed vaccines in the Americas. As for reverse zoonoses in endangered species, solutions require changing human behavior and policies at all levels impacting wildlife. Overall, continuous surveillance and viral discovery in humans and animals remain core components of a one-health approach to reduce and, where possible, eliminate zoonotic and reverse zoonotic diseases. Viral zoonosis and viral reverse zoonosis focusing on recent influenza A virus disease events in humans and other species are the subjects of the companion Currents in One Health by Kibenge, AJVR, June 2023.
Meloidogyne paramali n. sp. (Nematoda: Meloidogyninae) and First Report of M. marylandi in maple and yacca tree from Japan
Authors: Gu Jianfeng , Fang Yiwu , Ma Xinxin , Shao Baolin , Zhuo Kan 
Published: April 2023

Abstract

Meloidogyne paramali n. sp. was detected from Japanese maple trees (Acer palmatum) from Chiba, Japan during quarantine inspections in China. This species is characterized by second-stage juveniles (J2) with short tail length 32.2 (24–36.8) μm, finely rounded to broadly pointed tail terminus with extremely short hyaline tail terminus 4.3 (3.0–4.9) μm; perineal patterns of females characterized by an oval or irregular appearance, with round and low dorsal arch, and fine and smooth striae. M. paramali n. sp. is very similar to M. mali in that the perineal pattern has fine, smooth striae and both J2 have a short tail, but it can be distinguished from the latter by perineal pattern of the female (lateral field distinct vs. indistinct), shorter J2 hyaline tail terminus (4.3 [3.0–4.9] μm vs. 8.2 [4.8–12.7] μm, and by J2 tail with finely rounded to broadly pointed tail terminus, never sharply pointed vs. finely rounded and almost pointed. The polytomous key codes of the new species are as follows: Female: A21, B2, C32, D4; Male: A21, B3, C2, D1, E2, F2; J2: A2, B23, C43, D34, E12, F34. Detailed phylogenetic analysis based on partial 18S, ITS, D2-D3 28S, and partial mtCOI sequences also confirmed it as a new species, which is very close to M. mali and M. vitis and forms molecular group VIII. M. marylandi and other Meloidogyne species detected from plants from Japan in China are also discussed.
Intermittent fever and cough in a 56-year-old patient: Relapsing polychondritis and extranodal NK/T-cell lymphoma
Authors: Huang Qin , Cui Danyu , Chen Jianhui , Ren Hao , Yang Min 
Published: April 2023

Abstract
Relapsing polychondritis (RP) is a rare autoimmune disease in which recurrent and progressive chondritis occurs throughout the body. We report a case of a 56-year-old female subject presented as intermittent fever and cough, who was found obvious luminal stenosis and intense 18F-fluorodeoxyglucose (FDG) uptake in her larynx and trachea via bronchoscopy and FDG positron emission tomography/computed tomography (PET/CT). The auricular cartilage biopsy demonstrated chondritis. At first she was diagnosed as RP and treated by glucocorticoid and methotrexate, leading to completely response. Fever and cough recurred after 18 months, and FDG PET/CT were performed again and targeted a newfound nasopharyngeal lesion, where the biopsy proved to be an extranodal natural killer (NK)/T-cell lymphoma, nasal type.
Features of the tissue repair process in urgent surgical abdominal pathology in combination with COVID-19
Authors: Vlasov A. P. , Markin O. V. , Shchapov V. V. , Sitdikov I. I. , Zakharov A. A. , Shindakov V. G. , Babiker M. O. 
Published: April 2023

The OBJECTIVE was to study the process of wound healing after surgical interventions in patients with urgent surgical diseases in combination with a new coronavirus infection.METHODS AND MATERIALS. We observed for 80 patients with urgent abdominal diseases. Group I – 48 patients with various urgent diseases of the abdominal organs, group II – 32 patients with similar diseases occurring against the background of coronavirus infection. Stages of postoperative examination: 2, 4 and 7 days after surgery. The nature and rate of wound regeneration was assessed by cytological examination of wound exudate. In the tissues along the suture line, trophic indicators and microcirculation were recorded.RESULTS. The number of neutrophilic leukocytes in the wound exudate in group II exceeded the values of group I by 38.7–116.8 % with a slowed down dynamics of recovery. In the II group of patients, the number of tissue polyblasts was reduced at all stages of observation in comparison with the control group by 34.2–41.9 %. The number of lymphoid polyblasts in the main group was increased in comparison with the control group on days 2, 4, 7 of observation by 33.1 %, 63.2 %, 354.9 %, respectively. The indices of microcirculation in the tissues of the laparotomic wound in the group II of patients changed to a greater extent. The redox potential and oxygen diffusion coefficient in the group II were lower than the control figures by 9.8 – 37.2 % and 35.3 – 38.1 %, respectively. The number of complications according to the Clavien – Dindo classification in the group II of patients compared to the group I was more than 6 times higher.CONCLUSION. In patients with urgent diseases of the abdominal organs with concomitant coronavirus infection, the process of incomplete reparative tissue regeneration of the wound area slows down, which increases the risk of complications. The main factors that reduce the rate of tissue healing are disorders of microcirculation and bioenergetics.
Long-term results of minimally invasive deep reflux correction in patients with post-thrombotic disease
Authors: Shanaev I. N. , Khashumov R. M. 
Published: April 2023

The OBJECTIVE was to trace the long-term results of the operation of a dosed narrowing of the femoral vein in the lower third of the thigh proposed by Professor P. G. Shvalb.METHODS AND MATERIALS. The study included 30 patients (20 men and 10 women) with post-thrombotic disease of the veins of the lower extremities of the recanalized form, C4–C6, who underwent surgical correction of deep reflux in the period from 2012 to 2013. In 23 patients, additional phlebectomy of superficial and perforating veins was performed. The research method was duplex scanning (DS). The ratio of antegrade and retrograde blood velocities was used to quantitatively characterize deep reflux. Additionally, the state of the popliteal-tibial segment of the deep veins was determined using the Psatakis reflux index.RESULTS. The positive effect of the operation was noted in 96.7 % of patients at a follow-up period of 4 years. During follow-up periods of up to 8 years, the numbers decreased to 60.7 %. Relapse of trophic ulcers occurred in 39.3 % of patients. However, all patients noted that ulcers were much smaller in size than before surgery. According to DS data, incompetent perforator veins were detected in 16 patients: in all nine patients with recurrent ulcers and in seven patients without worsening. Vein diameter, maximum and average velocities of retrograde blood flow were greater in patients with worsening: diameter – 4.2±0.5 mm, υ (m) 91.2±19.8 cm/s, υ (average) 90.5±18.5 cm/s versus a diameter of 2.9±0.5 mm, υ (m) 39±15.6 cm/s, υ (average) 35±9 cm/s (p<0.05).CONCLUSIONS. Operation of dosed narrowing of the femoral vein had good clinical results in 96.7 % of follow-up periods up to 4 years, 60.7 % – after 8 years. Isolated correction of deep reflux with the preservation of insufficient perforator veins can lead to recurrence of trophic ulcers.
Diagnostic and therapeutic possibilities of laparoscopic and robotic technologies in blunt abdominal trauma (systematic review of the literature)
Authors: Karsanov A. M. , Maskin S. S. , Aleksandrov V. V. , Matyukhin V. V. 
Published: April 2023

INTRODUCTION. The development of laparoscopic and robotic surgery in medicine is happening rapidly, but their role and place in the surgery of blunt abdominal trauma are not yet fully defined, the range of diagnostic capabilities and performed operations is constantly expanding, contraindications are decreasing.The OBJECTIVE was to conduct systematic review based on modern data from Russian and foreign literature to determine the role and place of laparoscopic and robotic technologies in the diagnosis and treatment of patients with blunt abdominal trauma. The systematic literature search was conducted from January 2015 to August 23, 2021.Laparoscopy reduces the duration of inpatient treatment, the percentage of postoperative complications and mortality in hemodynamically stable patients with blunt abdominal trauma compared to laparotomy.CONCLUSION. To obtain data of a higher Level of Evidence and Grade of Recommendations, it is necessary to further conduct systematic reviews and meta-analyses based on randomized clinical trials.
Characteristics of Instant Steamed Sponge Cake Flour from Blending Purple Sweet Potato Flour (Ipomoea batatas var ayumurasaki), Mung Bean Flour ( (Vigna radiata) and Corn Flour ( Zea mays)
Authors: Yenrina Rina 
Published: April 2023

This research aims to get the best formulation which liked by panelist by considering the chemical characteristics from blending of purple sweet potato flour, mung bean flour and corn flour. This research has done at laboratory of agricultural technology, Andalas University, Padang on October until November 2021. The research has used Completely Randomized Design with 5 treatment and 3 repitition. Anlysis of data use Analysis of Varian ( ANOVA), obvious difference result will be continued with Duncan’s New Multiple Range ( DMRT) at 5% obvious level. Some treatment are blending purple sweet potato flour, mung bean flour and corn flour they are A (40% : 60%), B ( 40% :50% : 10%), C (40%: 40% : 20%), D ( 40% : 30% : 20% and E ( 40% : 20% : 40%). The research result indicate that blending of purple sweet potato flour, mung bean flour and corn flour is obvious significantly influenced to some analysis of water, ash, fat, protein,carbohidrate,antioxidan activity, water activity, crude fiber instant steamed sponge cake flour.