bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Survival Analysis of Family Forest Owners in the USA: Estimating Life Expectancy and 5-year Survivorship
Authors: Caputo Jesse , Butler Brett , Markowski-Lindsay Marla , Catanzaro Paul 
Published: May 2023

Abstract
Individuals, families, and trusts own a plurality of forest land in the United States, and the decisions made by these landowners have substantial impacts on the ecological, economic, and social benefits their lands provide. Some of the most impactful decisions include when and to whom to sell or leave their forested land, and whether or not to actively manage. Family forest landowners constitute an older population relative to the general population, and, the life expectancy of these landowners is a critical factor determining future land transitions, as well as patterns of management and land use. In this paper, we conduct a survival analysis using life tables and estimate that the average family forest landowner in the USA has a life expectancy of 21.0 additional years and an 89.3% chance of surviving the next five years. Five-year survivorship is a significant predictor of future plans to transfer land, as well as future intentions to actively manage. Additionally, at least in the Northeastern USA, survivorship significantly predicts filing wills and establishing land trusts. These results suggest that landowners may be consciously or subconsciously aware of their declining life expectancy and may be taking it into account when making decisions regarding estate planning and land management.
Social Group Optimization Algorithm with Dynamic Disturbance Strategy
Authors: Wang Ye , Lin Yisen , Qu Huichen , Wang Ruyue 
Published: May 2023

Abstract

In order to improve the convergence accuracy and speed of social group optimization algorithm, so as to improve the overall performance of the algorithm, a social group optimization algorithm with dynamic disturbance strategy( DDSGO) is proposed. The proposed algorithm improved the initialization population and the two learning stages in the SGO algorithm respectively. When initializing the population, the DDSGO algorithm replaces the initial population generated randomly with a reverse learning strategy to ensure that the diversity of the population is improved; In the improvement stage, the dynamic self-reflection coefficient is used to expand the search range of the optimal solution in the initial stage, and accelerate the speed of the population convergence to the optimal solution in the later stage, so that the population as a whole can quickly converge to the optimal solution. In the acquisition stage, the tent mapping is used to generate chaotic disturbance to increase the diversity of the population, which can increase the possibility of the algorithm jumping out of the local optimal solution. The experimental results based on the standard test function show that the proposed DDSGO algorithm is significantly improved in terms of convergence speed, convergence accuracy and stability compared with the comparison algorithms, and the overall performance of the algorithm is improved. The DDSGO algorithm has been used to solve the pressure vessel design optimization problem in order to further verify the effectiveness of the DDSGO algorithm. The experimental results show that the DDSGO algorithm is superior to the comparison algorithms, which proves that the DDSGO algorithm can be used to optimize the actual engineering design optimization problem.
Unveiling the Sweetness: Evaluating Yield and Quality Attributes of Early Generation Sweet Corn (Zea mays L.var. saccharata) Inbred Lines through Morphological, Biochemical and Marker-based Approaches.
Authors: Usman Shah Mohammad , Shikari Asif Bashir , Bhat Muhammad Ashraf , Wani Shabir Hussain , Yousuf Nida , Waza Showkat Ahmad , Khan Raheel Shafeeq , Shazia F , Sheikh Faroq Ahmad 
Published: May 2023

Abstract
Background Sweet corn is gaining tremendous demand worldwide due to urbanization and changing consumer preferences. However, genetic improvement in this crop is limited due to narrow genetic base and other undesirable agronomic traits that hinders the development of superior sweet corn genotypes.Methods A study was undertaken to carry out morphological and biochemical evaluation of 80 early generation inbred lines (S2) of sweet corn that were developed from a cross between two sweet corn hybrids (Mithas and Sugar-75) at Mountain Research Centre for Field Crops, Khudwani, SKUAST Kashmir during Kharif 2020. Furthermore, validation for favourable recessive alleles for sugar content was also done using SSR markers. The 80 sweet corn inbreds evaluated for phenotypic characterization showed wide range of variability with respect to different traits studied. The highest content of total carotenoids was found in the inbred S27 (34µgg− 1) followed by the inbred S65 (31.1µgg− 1). The highest sugar content was found in the S60 (8.54%) followed by the S14 (8.34%). Comparing the results of scatter plot for biochemical traits with morphological traits, it was revealed that inbreds S9, S23, S27 and S36 contains high levels of total sugars and total carotenoids along with moderate values for yield contributing traits indicating that these inbred lines could be utilized as source of favourable alleles in sweet corn breeding programmes after further validation for yield attributes, disease resistance and other preferable agronomic traits.Conclusion The results of the present study, has identified several inbreds harbouring desirable biochemical and agro morphological attributes related to high yield. Consequently, the study will not only enhance the genetic base of sweet corn germplasm but will also lead to development of high-yielding hybrids with improved quality. Molecular characterization of 60 inbred lines led to the identification of seven inbreds viz., S21, S28, S47, S48, S49, S53, and S54, which were sugary at both the loci (umc2061 and bnlg1937) and were also found to possess high sugar content through biochemical analysis, indicating their potential as desirable candidates for breeding programs aimed at improving sweet corn yield and quality. These findings demonstrate the effectiveness of these molecular markers in facilitating marker-assisted selection for important traits in sweet corn breeding.
Pharmacogenetic and clinical predictors of voriconazole concentration in hematopoietic stem cell transplant recipients receiving CYP2C19-guided dosing
Authors: Robinson Myra , Morris Sarah , Jandrisevits Elizabeth , Lopes Karine , Hamilton Alicia , Steuerwald Nury , Druhan Lawrence , Avalos Belinda , Copelan Edward , Ghosh Nilanjan , Grunwald Michael , Patel Jai 
Published: May 2023

Abstract
CYP2C19-guided voriconazole dosing reduces pharmacokinetic variability, but many patients remain subtherapeutic. The aim of this study was to evaluate the effect of candidate genes and a novel CYP2C haplotype on voriconazole trough concentrations in patients receiving CYP2C19-guided dosing. This is a retrospective candidate gene study in allogeneic hematopoietic cell transplant (HCT) patients receiving CYP2C19-guided voriconazole dosing. Patients were genotyped for ABCB1, ABCG2, CYP2C9, CYP3A4, CYP3A5, and the CYP2C haplotype were genotyped. Of 185 patients, 36% were subtherapeutic (of which 79% were normal or intermediate metabolizers). In all patients, CYP2C19 (p < 0.001), age (p = 0.018), and letermovir use (p = 0.001) were associated with voriconazole concentrations. In the subset receiving 200 mg daily (non-RM/UMs), CYP2C19 (p = 0.004) and ABCG2 (p = 0.015) were associated with voriconazole concentrations; CYP2C19 (p = 0.028) and letermovir use (p = 0.001) were associated with subtherapeutic status. CYP2C19, ABCG2, age, and letermovir use were associated with voriconazole concentrations and may be used to improve voriconazole precision dosing.
Systematic Photophysical Interaction Studies Between Newly Synthesised Oxazole Derivatives and Silver Nanoparticles: Experimental and DFT Approach
Authors: Mannopantar Santosh R , Patil V. S. , Prabhala Pavankumar , Lalasangi A. S. , Kalasad M. N. , Kulkarni Vijay. K. 
Published: May 2023

Abstract
In this study, the photophysical properties of oxazole derivatives such as 5-(furan-2-yl) -4-tosyloxazole (OX-1) and 5-(2-bromothiazol-4-yl)-4-tosyloxazoles (OX-2) were investigated using theoretical and experimental techniques. The ground and excited state dipole moments were empirically obtained utilising the solvatochromic shift technique and several solvatochromic correlations such as Lippert's, Bakhshiev's, KawskiChamma- Viallet's, and solvent polarity equations. The ground state dipole moments, HOMO-LUMO and molecule electrostatic potential map were also computed using ab initio calculations and evaluated using Gaussian 09 W software. Furthermore, spectroscopic interactions between newly synthesised dyes (OX-1 and OX-2) and freshly synthesised silver nanoparticles (size 40 nm) were studied. Increased absorbance and widening of absorption spectra for both dyes in the presence of varied quantities of silver nanoparticles show the potential of dye-nanoparticle interactions. Fluorescence quenching has been detected for both dyes in the presence of colloidal silver nanoparticles, indicating dynamic quenching, and a significant overlap between the absorption and emission spectra of the silver nanoparticle reveals that fluorescence quenching is also due to energy transfer.
Psychometric properties of the RED-Technostress questionnaire in Peruvian workers
Authors: Shimabukuro-Lara Jose , Ayala-Napan Roberto , Neyra-Ruiz Natalia , Nuñez-Mendoza Jiro , Quispe-Linares Rodrigo , Reyes-Perez Moises , Facho-Cornejo Jhoselit , Gomez-Fuertes Alberto , Álvarez-Huari María , Piedra Dina Calonge-De la 
Published: May 2023

Abstract

Background
Technostress is defined as the restlessness, fear, tension and anxiety that arises when learning and using technologies related to the use of the computer, directly or indirectly, and that, in the last place, ends with a psychological and emotional rejection that prevents continue to learn or use such technologies. This research aimed to adapt to the Peruvian context and evaluate the psychometric properties of the RED- technostress questionnaire, to demonstrate the validity and reliability of this instrument within the implementation in Peruvian organizations.
Methods and measures
258 workers participated online, mainly from the Lima-Peru region, who were working at the time of answering the questionnaire, removing those cases that showed univariate atypical influences.
Results
Content-based validity evidence was obtained; based on internal structure, through confirmatory factor analysis, obtaining acceptable goodness-of-fit indices with a second proposed model, removing three elements; and based on relation to other constructs. Likewise, acceptable reliability values ​​were found for the second model.
Conclusion
The RED- technostress questionnaire is valid and reliable to apply in the Peruvian context and it is recommended to use the model proposed in this research.
Modeling Roadway Temperatures for Wildfire Evacuation and Assessment of Pavement Damage
Authors: Barzegar Mohammadreza , Wen Haifang 
Published: May 2023

Abstract
Wildfires can cause enormous loss of assets and human lives, and thus, timely evacuation from the wildfire zone is critical to saving lives. Understanding evacuation route conditions, including traffic and temperature data, is imperative for safe evacuation. This study modeled the temperature conditions of an evacuation roadway within a wildfire zone, using the 2018 Camp Fire in Butte County, California as an experiment. The numerical modeling program, FlamMap, was used in this study to analyze the temperature conditions of an evacuation route. The results show that the temperature of the evacuation roadway increased quickly in a matter of a few hours. The change of roadways temperatures ranged from 3⁰C to 297⁰C within five hours after ignition, depending on the specific location along the roadway and other conditions. The results from this study can be used to understand temperature conditions for effective evacuation and to estimate roadway damage as well.
The synergic impacts of salt mixture and frost damage on rock decay: implications for the deterioration of rock-hewn heritages
Authors: Wang Yinghong , Zhang Hui 
Published: May 2023

Abstract

Soluble salt and freeze-thaw are two significant weathering factors inducing deterioration in rock-hewn heritages. While much research has focused on the influences of salt weathering and freeze-thaw separately, a realistic scenario reveals that the two processes often coincide in nature, making rock's decay process more complex and faster. We investigate how the synergic impact of salt weathering and freeze-thaw affect the severity of deterioration on rock-hewn heritage using materials and climatic conditions informed by rock-hewn heritage sites in SE China. The experiment was carried out on five types of stones sampled from the area of or close to the World Heritage Site, the West Lake Cultural Landscape of Hangzhou (WLCL), China. Samples were subject to 25 ageing cycles that comprised three phases: salt impregnation phase in 20℃/3hrs + freezing phase in -10℃/15hrs + evaporation phase in 50℃/6hrs). The mixture of Na2SO4-MgSO4 was utilised as the contamination substance based on the salt content determination of the stone heritage in the WLCL. Deterioration patterns, dimensional changes, pore structure and physic-mechanical properties, including surface hardness and splitting tensile strength, were determined. Results showed that the significant porous stone (porosity > 5%) with a higher proportion of micropores, e.g. flint, was more susceptible to the salt mixture, demonstrating pronounced surface detachment, deformation and strength decline. Dolomitic-rich carbonate stone with low porosity also shows deterioration, though their dimensional expansion and decline in mechanical properties are relatively minor. Most rock specimens' pore size distribution shifts to a higher magnitude, causing an enlargement in their average pore radius and an increase in mesopores. The relatively compact dolomitic limestone specimens developed new pores with a mean pore diameter of 6.5nm. This suggests that combining the two weathering factors would damage the appearance and nature of rock-hewn heritage by reshaping pore structure, weakening the cohesion between grains and consequently damaging the rock's initial fabric and strength.
Balance Disorders and Pain: An Analysis Based on the 2003-2004 NHANES Survey After Propensity Score Matching.
Authors: Tu Xiaoxian , Hu Feng , Tu Zhiyuan , Zhang Wenming , wu zhe 
Published: May 2023

Abstract
Purpose
Using a statistical approach to causal inference, to test the association between balance disorders and pain, providing a higher level of evidence.
Methods
Analysis of the Prevalence of Balance Disorders and Pain Based on NHANES Data To analyze the difference between the prevalence of pain in the balance disorder population and the balance population, logistic analysis was used to calculate the odds ratio (OR) of the effect of balance disorder on pain. Differences between groups and odds ratios were then calculated after propensity score matching of the two groups according to demographic characteristics.
Results
The weighted prevalence of balance disorders was 26.09%, and the weighted prevalence of pain, neck pain, and low back pain was 48.25%, 22.63%, and 39.22%, respectively. The prevalence of pain, neck pain, and low back pain was higher in the pre- and post-matched pain disorder group than in the balanced group(Before PSM, pain, 605(71.94%) VS 1070(48.09%), 95%CI ,20.17–27.53%. After PSM, pain, 605(71.94%) VS 409(48.63%), 95%CI, 18.76–27.85%). Multifactorial logistic regression, controlling for other variables, showing pain odds ratios associated with balance disorders (Before PSM, OR, 2.61, 95%CI, 2.192 to 3.110, p < 0.001. After PSM, OR, 2.747, 95%CI, 2.240 to 3.370, p < 0.001).
Conclusion
In the U.S. adult population over the age of 40, those with balance disorders had more pain, neck pain, and low back pain than those without balance disorders; there is a strong association between balance problems and pain. Balance is a risk factor for pain.
Kinetics of COVID-19 mRNA primary and booster vaccine-associated neutralizing activity against SARS-CoV-2 variants of concern in long-term care facility residents: A prospective longitudinal study
Authors: Kakugawa Tomoyuki , Doi Keiko , Ohteru Yuichi , Kakugawa Hiroyuki , Oishi Keiji , Kakugawa Masahiro , Hirano Tsunahiko , Mimura Yusuke , Matsunaga Kazuto 
Published: May 2023

Abstract
Background
Coronavirus disease 2019 (COVID-19) remains a threat to vulnerable populations such as long-term care facility (LTCF) residents, who are often older, severely frail, and have multiple comorbidities. Although associations have been investigated between COVID-19 mRNA vaccine immunogenicity, durability, and response to booster vaccination and chronological age, data on the association of clinical factors such as performance status, nutritional status, and underlying comorbidities other than chronological age are limited. Here, we evaluated anti-spike IgG and neutralizing activity against the wild-type virus and Delta and Omicron variants in the sera of LTCFs residents, outpatients, and healthcare workers before the primary vaccination, at 8, 12, and 24 weeks after the primary vaccination, and approximately 3 months after the booster vaccination. This 48-week prospective longitudinal study was registered in the UMIN Clinical Trials Registry (Trial ID: UMIN000043558).
Results
Of 114 infection-naïve participants (64 LTCF residents, 29 outpatients, and 21 healthcare workers), LTCF residents had substantially lower anti-spike IgG levels and neutralizing activity against the wild-type virus and Delta variant than outpatients and healthcare workers over 24 weeks after the primary vaccination. In LTCF residents, booster vaccination elicited neutralizing activity against the wild-type virus and Delta variants comparable to that of outpatients, whereas neutralizing activity against the Omicron variants was comparable to that of outpatients and healthcare workers. Multiple regression analyses showed that age was negatively correlated with anti-spike IgG levels, neutralizing activity against the wild-type virus, and Delta variant after the primary vaccination. However, multivariate regression analysis revealed that poor performance status and hypoalbuminemia were more strongly associated with a lower humoral immune response than age, number of comorbidities, or sex after primary vaccination. In contrast, booster vaccination counteracted the negative effects of poor performance status and hypoalbuminemia on humoral immune response.
Conclusions
LTCF residents exhibited suboptimal immune responses following primary vaccination. Although older age is significantly associated with a lower humoral immune response, poor performance status and hypoalbuminemia are more strongly associated with a lower humoral immune response after primary vaccination. Thus, booster vaccination is beneficial for older adults, especially those with a poor performance status and hypoalbuminemia.
Effects of grazer density, season and landcover on bird guilds in a restored conservation area
Authors: Lovász Lilla , Korner-Nievergelt Fränzi , Amrhein Valentin 
Published: May 2023

Abstract
Context Grazing by large herbivores is an increasingly used management tool in European nature reserves. A challenge in grassland conservation is to maintain both the openness and the heterogeneity of the habitat, to support their animal communities, including birds. Horses and cattle are often used to create and maintain patchy landscapes, especially in rewilding projects, but the influence of grazers on birds is often debated by conservationists.Objectives We studied how the abundance and species richness of birds of four foraging guilds are related to the area use of Highland cattle and Konik horses in an alluvial grassland. We also investigated how season and landcover influences the spatial distribution of individuals and species of different bird guilds on the grazed area.Methods We equipped all grazers with GPS-collars to assess the density of their hourly positions. We made weekly transect counts of birds to describe their distribution, and carried out landcover surveys to describe the habitat. We used GAMM models in a spatially explicit framework.Results Open-area foraging birds were clearly associated with higher grazer densities, and aerial, wetland and woodland birds also seemed to profit from low-intensity year-round grazing. Most bird species and individuals were observed on open landscapes scattered with woody patches and waterbodies, and at areas with moderate grazer density. The number of birds on the grazed area was about twice as on the ungrazed control area.Conclusions A heterogenous landscape maintained by low-intensity grazing seems to fulfil the needs of birds with different feeding ecologies.
In silico studies of N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl) piperazine-1-carboxamide derivatives as potent TRPV1 antagonists using 3D QSAR, ADMET and Molecular Docking
Authors: TOUGHZAOUI Abdelilah , CHEDADI oussama , AISSOUQ Abdellah EL , Ouardi youssef El , BOUACHRINE Mohammed , OUAMMOU Abdelkrim , MORADI kamal 
Published: May 2023

Abstract
TRPV1 is a promising therapeutic target given its involvement in pain management and inflammation. TRPV1 antagonists are increasingly sought after for their analgesic, anti-inflammatory and antitumor properties with fewer side effects. This study focused on the design of new effective TRPV1 antagonists by replacing the pyridine ring of BCTC with a pyrimidine ring. Significant 3D-QSAR models were developed using CoMSIA and CoMFA methods and showed a satisfactory correlation between experimental and predicted activity (Q2 = 0.715; R2 = 0.988; SEE = 0.048). Electrostatic, hydrophobic fields and hydrogen bond acceptors contributed significantly to the biological activity of studied compounds. Molecular docking analysis validated the 3D-QSAR models and explained the interactions of the most active ligands with the binding site. These results permitted prediction of new compounds, whose pharmacokinetic properties, toxicity and pharmacodynamics effects were assessed using ADMET and drug similarity.