bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH IKLIM ORGANISASI TERHADAP KEPUASAN KERJA YANG BERDAMPAK PADA LOYALITAS KARYAWAN PT TELKOM AKSES WILAYAH TELKOM SURABAYA UTARA
Authors: Jatmiko Tri , Aribowo Handy , Iswati Iswati 
Published: July 2023

This study aims to analyze and determine the effect of Organizational Climate and Job Satisfaction on Employee Loyalty of PT Telkom Access Telkom North Surabaya Region. This study uses quantitative research with a population of all employees of PT Telkom Access Telkom North Surabaya. Sampling is in accordance with Ferdinand's opinion, so that the research sample obtained is 120 respondents. Using multiple linear regression analysis with t test as a hypothesis test. The results showed that Organizational climate had a significant effect on Employee Satisfaction at PT Telkom Access Telkom North Surabaya with a magnitude of 0.433 or 43.3% with a positive direction of influence, Organizational climate had a significant effect on employee loyalty at PT Telkom Access Telkom North Surabaya with a magnitude of influence of 0.308 or 30.8% with a positive direction of influence. Employee Satisfaction has a significant effect on Employee Loyalty at PT Telkom Access Telkom North Surabaya with a magnitude of influence of 0.274 or 27.4% with a positive direction of influence
Keywords: Organizational Climate, Employee Satisfaction, dan Employee Loyalty
On the Difference in Cycling Pattern on Linear and Higher-Order Effect Designs
Authors: Ikpan Okim I. , Nwobi Felix N. 
Published: July 2023

D-optimality is a design criterion that seeks to maximize the determinant of the information matrix, or equivalently minimize the determinant of the inverse information matrix of the design. This design criterion results in maximizing the differential Shannon information content of the parameter estimates. Cycling, a phenomenal problem associated with the construction of optimal designs, impedes the rate of convergence to such desired optimum, whenever it occurs in a variance exchange process. Different polynomial functions may have varying effects on the pattern of convergence due to cycling. This paper seeks to determine the nature and extent to which the influence of cycling affects the pattern of convergence on Linear, Interactive, and Quadratic order effect designs. The variance exchange algorithmic search method was adopted based on the philosophy of numerically searching the design space for optimum designs. Two and three-variable response functions are used in the investigation of even and odd-sized point designs. Generated data from designs of sizes 10 and 11 were employed in the investigation. Numerical illustrations were given to ascertain the pattern of convergence on each of the degree polynomial designs. The computations and graphs were conducted in R version 4.1.1 (2021). The results show that cycling patterns differ with respect to the degree of the response function whether it is of even or odd-sized design, or has two or three variables. The result will enable researchers to find appropriate measures to accommodate the challenge posed by cycling.
Estimation of Greenhouse Gas Emissions and Absorption from the Agriculture, Forestry and Other Land Use Sector in the Monomodal and Bimodal Rainfall Forest Agroecological Zones of Cameroon
Authors: Amougou Joseph Armathé , Mbomba Forghab Patrick , Ebokona Lucas Dominique Bembong , Fuh Geh Kisito , Freddy Bikono Pascal , Amadou Garga , Iyawa Faiza , Abdouraman  , Armstrong Enoh Ayuk Michael Daniel , Ghislaine Bangdang Yolande , Prisca Mewamba Ariane , Teclaire Ngoh Njoume Ndedie , Arielle Maliedje Tabuguia 
Published: July 2023

This greenhouse gas (GHG) accounting study of the Agriculture, Forestry and Other Land Use sector assesses carbon emissions and absorption for the period 2010 to 2018 in the Monomodal and Bimodal rainfall agroecological zones. The methodological approach used for GHG emissions calculations in the Livestock category is the one proposed by the Intergovernmental Panel on Climate Change (IPCC) 2006 guidelines, taking into account the national systems of other countries. In general, Tier 1 has been used for the calculation of emissions. Emissions/removals are calculated by integrating the activity data of the different sectors considered in the IPCC software. In the subcategory of land use change, the SEPAL platform and ArcGis 10.6 software were used to download and process the images. In addition, the Peng (2000) equation was used to assess the soil organic carbon stock.
Emissions from the two agroecological zones are 281,541.3 GgCO2Eq and absorptions are -2,924,841.22 GgCO2Eq. The potential carbon stock that can be recovered in the two agroecological zones is -2,643,299.92 GgCO2Eq.
It is clear that these two agroecological zones absorb more than they emit. These results show that the Bimodal and Monomodal rainfall agroecological zones have a high absorption potential that Cameroon could use in the framework of internationally transferable mitigation results.
Effect of Orally Administered Dennettia tripetala (Pepper Fruit) (Aq) Extract on the Intraocular Pressure and Serum Concentration of Lipid Parameters of Wistar Strain Albino Rat
Authors: Isdore Uzoamaka Donald , Ekenze Chigozie John , Owunna Lilian Chioma , Ogundeko Timothy Olugbenga , Ramyil Mamzhi Seljul Crown , Okoye Nkiruka Philomena , Bassi Amos Paul 
Published: July 2023

Background: Plant parts have continued to attract attention in the global search for natural means of treatment of many diseases affecting humans and animals including glaucoma.
Aims: The present study was designed to evaluate the effect of Aqueous seed extract of Dennettia tripetala (ASEDt) on the intraocular pressure (IOP) and the serum concentration of lipid parameters of Wistar strain albino rats (male and female).
Methodology: This study was conducted in the Optometry and Anatomy department of Abia state University Uturu, Nigeria where a total of 37 males albino Wistar rats (12 weeks old), weighing 200 – 230g were used (12 for acute toxicity studies and 25 for the experiment proper) for a period of 35 days. The 25 rats were further divided into 5 groups (A-E) of 5 animals each according to various treatments A- No treatment, B-10mg/ml Cholesterol p.o, while C, D and E were treated with 10mg/ml Cholesterol p.o, plus administration of 200mg DT seed (aq) extract, 500mg DT seed (aq) extract and 0.5% timolol topically into the eye respectively. Intraocular pressure as well as the serum concentration of lipid parameters of the control group viz; Total cholesterol (TC), Triglycerides (TG), High density lipoprotein (HDL) and Low-Density Lipoprotein (LDL) was measured at day 1 (Baseline) 10 and 20 of experiment.
Results: Topical administration of 200mg/kg and 500mg/kg DT seed (aq) extract caused a significant reduction of IOP in the rats. This reduction was higher with 500mg. Furthermore, both 500mg and 200mg (ASEDt)A caused a reduction in the levels of TC, TG, LDL and increased level of HDL.
Conclusion: Aqueous seed extract of Dennettia tripetala caused a dose dependent reduction of intraocular pressure and ameliorated the serum concentration of lipid parameters in both male and female Wistar strain albino rats, thus suggesting that it could be beneficial in peculiar ocular, cardiovascular and public health care management.
Isolation and Antibiotic Resistance of Staphylococcus aureus Isolated from Nosocomial Sources
Authors: Musa U. H. , Innocent I. G. , Dafur G. S. , Ola I. F. , Gowon A. G. , Julius E. E. , Suleiman M. 
Published: July 2023

Methicillin resistance Staphylococcus aureus have been reported worldwide to emerge mostly in developing and developed countries. This study aimed at isolated and antibiotic resistance from nosocomial sources in Dalhatu Araf specialist Hospital, Lafia, Nigeria. A total of (200) samples were collected from February 2021 to May 2021 from different Nosocomial sources such as door handles, seat handles, surgical equipment and stretchers and Staphylococcus aureus was isolated and identified using standard microbiological method. The Antibiotic susceptibility test for the isolates were carried out and interpreted in accordance with Clinical and Laboratory Standard Institute (CLSI) protocol. The occurrence of Staphylococcus aureus from the samples was 50 (25%). The highest occurrence of Staphylococcus aureus is from seat handle swab with (32%) and the lowest occurrence is (18%) from surgical equipments. The Antibiotic resistance of Staphylococcus aureus showed that the isolates were more resistant to oxacillin.
Engineering Covalent Aptamer Chimeras for Enhanced Autophagic Degradation of Membrane Proteins
Authors: Shi Yang , Yun Yangfang , Wang Rong , Liu Zheng , Wu Zhenkun , Xiang Yu , Zhang Jingjing 
Published: January 2025

AbstractTargeted degradation of membrane proteins represents an attractive strategy for eliminating pathogenesis‐related proteins. Aptamer‐based chimeras hold great promise as membrane protein degraders, however, their degradation efficacy is often hindered by the limited structural stability and the risk of off‐target effects due to the non‐covalent interaction with target proteins. We here report the first design of a covalent aptamer‐based autophagosome‐tethering chimera (CApTEC) for the enhanced autophagic degradation of cell‐surface proteins, including transferrin receptor 1 (TfR1) and nucleolin (NCL). This strategy relies on the site‐specific incorporation of sulfonyl fluoride groups onto aptamers to enable the cross‐linking with target proteins, coupled with the conjugation of an LC3 ligand to hijack the autophagy‐lysosomal pathway for targeted protein degradation. The chemically engineered CApTECs exhibit enhanced on‐target retention and improved structural stability. Our results also demonstrate that CApTECs achieve remarkably enhanced and prolonged degradation of membrane proteins compared to the non‐covalent designs. Furthermore, the CApTEC targeting TfR1 is combined with 5‐fluorouracil (5‐FU) for synergistic tumor therapy in a mouse model, leading to substantial suppression of tumor growth. Our strategy may provide deep insights into the LC3‐mdiated autophagic degradation, affording a modular and effective strategy for membrane protein degradation and precise therapeutic applications.
A C–H Arylation‐Based Enantioselective Synthesis of Planar Chiral Cyclophanes
Authors: Huh Soohee , Linne Elvira , Estaque Lilian , Pieters Grégory , Devereux Michael , Baudoin Olivier 
Published: January 2025

AbstractDespite the growing importance of planar chiral macrocyclophanes owing to their unique properties in different areas of chemistry, methods that are effective in controlling their planar chirality are restricted to certain molecular scaffolds. Herein, we report the first Pd(0)‐catalyzed enantioselective intermolecular C−H arylation that induces planar chirality by installing bulky aryl groups through dynamic kinetic resolution (DKR). A computer‐assisted approach allowed a fine‐tuning of the structure of the employed chiral bifunctional phosphine‐carboxylate ligands to achieve high enantioselectivities. A range of planar chiral macrocyclophanes were successfully synthesized from configurationally labile macrocyclic precursors via C−H arylation with various perfluoroarenes. Mechanistic investigations indicated that the reaction proceeds via reversible oxidative addition and enantiodetermining C−H activation. Selected macrocyclophane products showed interesting photophysical and chiroptical properties, which depended on both the nature of the ansa chains and the aromatic moieties.
In‐Situ Formation of Three‐Dimensional Network Intrinsic Microporous Ladder Polymer Membranes with Ultra‐High Gas Separation Performance and Anti‐Trade‐Off Effect
Authors: Sun Luxin , Xu Wei , Zhang Hongjun , Chu Jiachen , Wang Mengtao , Song Kai , Wu Wenjie , Li Jianxin , Wang Yingge , Pinnau Ingo , Ma Xiaohua 
Published: January 2025

AbstractThe global quest for clean energy and sustainable processes makes advanced membrane extremely attractive for energy‐intensive industrial gas separations. Here, we disclose a series of ultra‐high‐performance gas separation membranes (PIM‐3D‐TB) from novel network polymers of intrinsic microporosity (PIM) that combine the advantages of solution processible PIM and small pore size distribution (PSD) of porous organic polymers (POP), which was synthesized by in situ copolymerization of triptycene‐2,6‐diamine as linear part and triptycene‐2,6,13(14)‐triamine (TTA) as crosslinker. The resulting PIM‐3D‐TB membranes demonstrated outstanding separation properties that outperformed the latest trade‐off lines for H2/CH4 and O2/N2. They also showed an anti‐trade‐off effect by simultaneously enhancing gas permeability and gas‐pair selectivity with increasing TTA content. The TTA crosslinking node increased the microporosity, and, shifted the PSD from the ultramicropore (<7 Å) toward the more size sieving submicropore (<4 Å) region. The post‐treated TTA‐75 displayed an exceptional H2 permeability of 8000 Barrer and H2/CH4 selectivity of 208. These PIM‐3D‐TB membranes and their design protocol have unparalleled potential in the next generation of membranes for hydrogen purification and air separations.
Two Coordination Polymers Based on Rigid Benzimidazole Carboxylic Acid Ligands: Electrode Performance and Adsorption of Dyes
Authors: Liu Bo‐Yu , Zhao Jian , Zeng Tao , Yue Tian‐Cai , Wang Lu‐Lu , Wang Duo‐Zhi 
Published: January 2025

ABSTRACTTwo new cobalt‐based coordination polymers (CPs) based on two different benzimidazole carboxylic acid ligands, namely, {[Co(L1)(H2O)2]2SiF6·(H2O)2}n (1) and {[Co(L2)(H2O)2]2SiF6·(H2O)2}n (2) (HL1 = 2‐[1H‐imidazol‐5‐yl]‐1H‐benzimidazole‐6‐carboxylic acid and HL2 = 2‐[1H‐imidazol‐2‐yl]‐1H‐benzimidazole‐6‐carboxylic acid), were synthesized via solvothermally method. Structural analysis revealed that CP‐1 featured a two‐dimensional planar structure, while CP‐2 exhibited a one‐dimensional chain structure. CP‐1 achieved a specific capacitance of 658.6 F g−1 at a current density of 1 A g−1 and retained good capacitance after charge–discharge cycling tests. In addition, both CP‐1 and CP‐2 showed good adsorption performance for the anionic dye Congo red (CR), and the maximum adsorption capacities were 1256 and 2985 mg g−1, respectively.
Polyaspartic Acid–Based Porous Carbon–Loaded Nickel Metal and Its Application to Hydrogen Adsorption
Authors: Lu Mingqiu , Zhu Huimin , Liu Ling , Jiang Meilin , Shi Qiulan , Zhao Jianbo 
Published: January 2025

ABSTRACTHydrogen energy plays an important role as a clean, renewable resource in replacing traditional fossil energy sources, and in this study, a polyaspartic acid (PASP) porous carbon loaded with metallic nickel was prepared for hydrogen storage. The PASP porous carbon loaded with nickel metal was successfully prepared by high‐temperature pyrolysis and metal‐solution impregnation using homemade PASP hydrogels as raw material. Compared to ordinary carbon materials, the addition of K+ as a porogenic agent to the material before carbon formation makes its pore structure rich and adjustable. In addition, nickel as an active site optimizes the overall electronic structure and surface properties of the material, which together increase the gas adsorption capacity. The materials of PASP, PASP porous carbon, and PASP porous carbon loaded with metallic nickel were also characterized by FTIR, SEM, BET, TEM, EDS, XRD, and XPS, and finally applied to hydrogen adsorption. The results show that C‐PASP‐50% has the best adsorption effect on hydrogen with different degrees of cross‐linking, and the adsorption capacity can reach 126.49 cm3/g. The adsorption capacity increases significantly after loading metal nickel, and the adsorption capacity of C‐PASP‐Ni50% reaches 273.03 cm3/g.
NiCo2O4/P,N‐Doped Carbon with Engineered Interface to Improve the Rechargeability of Zn‐Air Batteries at High Energy Demands
Authors: Suárez‐Barajas Alexander , Guerra‐Balcázar Minerva , Ramos‐Castillo Carlos M. , Álvarez‐Contreras Lorena , Arjona Noé 
Published: January 2025

AbstractThe search for cost‐effective, high‐performance bifunctional catalysts for Zn‐air batteries (ZABs) requires extensive research into precious‐metal‐free materials. This study provides insight into the synergy between nickel cobaltite and P,N‐doped carbon modified through interface engineering by inducing oxygen vacancies in the spinel and non‐metallic heteroatoms in the carbon material. NiCo2O4 with various oxygen vacancy levels was synthesized via an ethylene glycol‐assisted solvothermal route. This resulted in significant changes in the structural and morphological properties, such as reduced crystallite size, lattice distortion, and increased oxygen vacancies, as observed from the physicochemical results. This was further verified by X‐ray photoelectron spectroscopy (XPS) and high‐resolution transmission electron microscopy (HR‐TEM), which showed a homogeneous dispersion of nickel cobaltite nanorods on the carbonaceous matrix, along with an increased concentration of pyridinic nitrogen and the formation of P−N and P−C bonds, both of which enhance electrocatalytic activity. NiCo2O4DI/P,N−C exhibited superior discharge polarization behavior, achieving power and current densities of 124.4 mW cm−2 and 215.8 mA cm−2. Stability tests revealed that the catalyst had excellent performance, lasting up to 100 h, while Pt‐IrO2/C lasted only up to 21 h. These results demonstrate the great potential of tailoring surface defects and heteroatom doping via interface engineering, resulting in high‐performance precious‐metal‐free electrocatalysts for long‐lasting and high‐efficiency ZABs.
Expediting Polysulfide Anchoring by Fe3O4/Reduced Graphene Oxide Composite for High‐Performance Lithium‐Sulfur Batteries
Authors: Ansari Tanwir , Ghosh Anamika , Ganguly Dipsikha , Muthiah Balasubramanian , Sundara Ramaprabhu 
Published: January 2025

AbstractThe inherent low conductivity of sulfur, sluggish redox kinetics, and the challenge of maximizing active material utilization are the bottlenecks for practical implementation in lithium‐sulfur (Li−S) battery technology. Herein, a low‐cost Fe3O4‐rGO that serves as both a sulfur host matrix and an electrocatalytic interlayer in a Li−S battery has been synthesized. With the merit of high specific surface area, Fe3O4‐rGO offers high sulfur loading (80 wt. %) and sufficient space to accommodate sulfur volume expansion during the redox reaction. The symmetric cell experiment demonstrated that Fe3O4 in the rGO structure promotes the lithium polysulfide (LPS) redox conversion. The Li−S battery is constructed using the Fe3O4‐rGO@S as the cathode and Fe3O4‐rGO as the interlayer, demonstrating an impressive specific capacity of 1258 mAh g−1 at 0.1 C and the battery retained 76 % of its capacity after 400 cycles at 0.5 C. This study also explores the confinement of LPS on the Fe3O4‐rGO@S_Fe3O4‐rGO cathode and interfacial redox kinetics by dynamic electrochemical impedance spectroscopy. This work presents a cost‐effective method for improving the catalytic conversion of lithium polysulfides, which can contribute to the development of high‐performance lithium‐sulfur batteries.
Seasonal Fluctuation in the Incidence of Congenital Hypothyroidism Across Different Temperate Zones of China
Authors: Yao Yongna , Deng Kui , Zhu Jun , Li Qi , Xiang Liangcheng , Yuan Xuelian , Wang Yanping , Liu Zheng , Tan Huiwen , Li Xiaohong 
Published: January 2025

ABSTRACTBackgroundSeasonality in the incidence of congenital hypothyroidism (CH) has been identified in several countries and different conclusions have been drawn. The objective of this study was to examine whether this seasonality is also observable in China and how it manifests across different temperate zones.MethodsData on CH cases and screened neonates between January 1, 2014, and September 30, 2022, by year and season, were sourced from the Chinese Newborn Screening Information System. The overall CH incidence and incidence across different temperate zones was analyzed by using the seasonal unit root test, seasonal decomposition, and deterministic seasonal means regression model.ResultsA total of 29,259 CH cases were reported nationwide from season one of 2014 to season three of 2022. Quarterly CH incidence showed an upward time trend and significant seasonality among all zones, but with different patterns. Overall, season one was the peak period with an incidence rate of 7.09 per 10,000 neonates, whilst season two was the trough period with an incidence rate of 5.89. Subtropical, warm, and medium temperate zones had one peak period in season one, whilst the tropical zone had two peak periods in seasons one and three. In comparison, the plateau zone had a trough season in season one.ConclusionOur study found the quarterly CH incidence exhibited clear seasonality, temperate zone‐specific patterns, and an upward time trend in China. This finding is particularly concerning given China's decline in the number of births, underscoring the urgency of allocating resources appropriately in screening programs.
Quantitative analysis of disaggregation properties of aggregation‐induced emission luminogens (AIEgens) and off‐the‐shelf dyes
Authors: Hong Kyung Tae , Jeon Jun‐Hyuk , Park Soeun , Gopala Lavanya , Lee Jane , Lee Jun‐Seok 
Published: January 2025

AbstractThe aggregation state of chemosensors significantly influences their photophysical properties, making it critical for their applications in sensing and imaging. In this study, we systematically investigated the disaggregation properties of 11 representative fluorophores, including widely used dyes such as BODIPY, coumarin, fluorescein, rhodamine B, and Nile Red, as well as AIEgens like TPE and TPA. Through a quantitative approach, we determined the disaggregation concentration (DC₅₀) in various aqueous‐organic co‐solvent mixtures and correlated these values with solvent polarity parameters, such as dielectric constant and ET(30). Our analysis uncovered distinct DC₅₀ patterns that act as unique fingerprints for each compound, reflecting their structural characteristics. Notably, structurally similar compounds, such as BODIPY derivatives and dansyl‐based chemosensors, exhibited comparable trends. This study underscores the utility of solvent polarity versus DC₅₀ scatter plots for evaluating aggregation‐dependent chemosensors and offers valuable insights into the molecular determinants of self‐aggregation, enabling more rational chemosensor design.
Manipulating photophysical properties through asymmetric modification of triptycene‐fused multi‐resonance TADF emitter
Authors: Mubarok Hanif , Lutfi Rafi Muhammad , Yun Jaemin , Jung Jaehoon , Lee Min Hyung 
Published: January 2025

AbstractDeveloping multi‐resonance (MR) effect‐induced thermally activated delayed fluorescence (TADF) emitters that exhibit excellent photophysical properties and a sterically shielded structure is crucial for achieving high‐efficiency and stable organic light‐emitting diodes (OLEDs). Herein, we propose a new synthetic approach to asymmetric bulky MR‐TADF emitters based on a B,N core. Three asymmetric Tp‐fused MR emitters (1–3) are produced by attaching a bulky and rigid triptycene (Tp) moiety on one side of the MR core and introducing different N‐containing functional groups on the other side. All emitters exhibit high photoluminescence quantum yield, narrow full width at half maximum, and TADF properties with reasonable reverse intersystem crossing rates (~104 s−1) in a rigid matrix. Notably, the emission color of the emitters ranges from deep blue to sky blue, depending on the N‐containing functional groups. Electrochemical and theoretical studies further demonstrate that the frontier molecular orbitals are distributed over the MR core formed by the two moieties, and the resulting energy levels vary accordingly. The findings of this study will be useful for the design of various color‐tunable yet sterically shielded MR‐TADF emitters.