bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of acceptability, microstructure, and resistant starch content of biscuits substitution of jack beans (Canavalia ensiformis) with starch modification of Annealing-HMT
Authors: Ariyantoro A R , Ishartani D , Yulviatun A , Attaqiyyah F 
Published: June 2023

Abstract
Biscuits as a ready-to-eat product with an average consumption growth per capita per year are always increasing, becoming a food product that is often explored for raw materials (especially with local ingredients) to replace the dependence on domestic wheat flour. One of the local ingredients that is rarely used as a food product is the jack bean (Canavalia ensiformis L.) with a high carbohydrate content of 50%–60%. It is suitable for processing into starch as a substitute for food products such as biscuits. The native jack bean starch needs to be modified by physical modification methods, namely, Heat Moisture Treatment (HMT) and annealing-HMT to improve its characteristics, which are less stable to mechanical and heat processes and to increase the levels of resistant starch. This research aimed to look for resistant starch content, microstructure, and the acceptability of jack bean biscuits with physical modification annealing-HMT. The experimental design was used a one-factor completely randomized design with variations of modified starch substitution in the biscuit formula that control sample made of 100% wheat flour: samples made of 50% and 100% for each native starch, HMT modified starch, and annealing-HMT modified starch. Based on the results, it was found that the substitution of wheat flour with annealing-HMT starch in the biscuit sample affected the microstructure of the resulting granules and the levels of resistant starch with the best sample using Annealing-HMT starch substitution (100%). Meanwhile, the results of the sensory test showed that the substitution of wheat flour with Annealing-HMT starch was significantly different in the color, texture, and overall parameters. The determination of the best formula in the sensory test was carried out by the Bayes method with the best formula results being samples with HMT modified starch substitution (100%).
Physical quality of beef sausage using porang flour as a substitute for tapioca flour
Authors: Nuhriawangsa Adi Magna Patriadi , Swastike Winny , Hertanto Bayu Setya , Hanifa Aqni , Kartikasari Lilik Retna 
Published: June 2023

Abstract
The aim of this study was to evaluate the physical quality of beef sausage using porang flour as a substitute for tapioca flour. The research material used beef (lean), tapioca flour, and glucomannan flour (porang). The sausage formula was the ratio of tapioca flour to porang flour which consisted of 10:0 (P0); 8:2 (P1); 6:4 (P2); 5:5 (P3); 4:6 (P4); 2:8 (P5), and 0:10 (P6) ratios. Beef sausage parameters included pH, cooking loss, water holding capacity (WHC), and tenderness. Data analysis used Unidirectional ANOVA and continued with Duncan’s test if there were significant differences between the treatments. The results of the study showed that there were differences in pH, WHC, and tenderness (P<0.01), but the cooking loss of beef sausage was not significantly different (P>0.05) among treatments. Unlike the P0 treatment, the values of pH, WHC, and tenderness of the P1-P6 treatments increased, but cooking loss remained the same. In conclusion, the use of the ratio of tapioca flour to porang flour (C5) on beef sausage has better quality than 10:0 (P0).
Development of breakfast food from black rice and porang supplemented with jackbean and red dragon fruit
Authors: Zhafira A S , Dwiyanti H , Aini N 
Published: June 2023

Abstract
This study aim to develop the potential of local food into functional breakfast cereal products that are high in energy and rich in dietary fiber, as an alternative breakfast food for individuals with diabetes. The sample formulation is a factorial experimental study using a Randomized Block Design. The factors are the proportion of composite flour consisting of black rice, porang, and jack bean flour also the addition of red dragon fruit concentrate based on the total weight of composite flour. The chosen breakfast cereal formulation contains moisture (6.07%bw), ash (4.87%bw), protein (8.68%bw), fat (0.38%bw), and carbohydrate (79.99%bw), and crude fiber (43.49%bw) which meets requirements of breakfast cereal in the SNI. It can be concluded that the chosen breakfast cereal is low fat and high fiber food product. Further research is needed to study the effectivity of chosen breakfast cereal on fasting blood glucose of people with diabetes.
Factors influencing consumer behavior towards the purchase decision of instant megono of Anglur Selur production Pekalongan City
Authors: Riskiana Irma , Wahyuningsih Sri , Awami Shofia Nur , Subekti Endah , Widiyani Aniya 
Published: June 2023

Abstract
Pekalongan City is an area that has a variety of traditional culinary, one of which is megono. Instant megono is a megono product that is preserved and produced by CV Anglur Selur Pekalongan City. This study aims to find out the factors that influence consumer behavior towards instant megono purchasing decisions. This study uses data analysis methods in the form of qualitative descriptive and quantitative analysis. Determination of the location of the study using the purposive sampling method while the determination of the sample of respondents used the accidental sampling method with 100 respondents. Data analysis uses multiple linear regression analysis. The results of the t-test show consumer habits (X1), family / friends / relatives as a reference (X2), income level (X3), lifestyle (X4), product price (X5), product availability (X6), self-confidence (X7), and self-encouragement (X8) significantly influenced the purchase decision of instant megono.
Effect of storage temperatures treatment of coconut flesh (Cocos nucifera L.) based on the quality of coconut milk
Authors: Alfian R N , Choirunnisa N I , Susilo B , Sandra  
Published: June 2023

Abstract
Coconut plant (Cocos nucifera) is one of the potential industrial plants and has an important role both in terms of nutrition and in terms of economy in Indonesia. The number of coconut plants in Indonesia is used by the community, one of which is as a raw material for making coconut milk. Coconut milk is obtained from the extract of old coconut flesh that has been grated, either with the addition or without water, this white coconut milk liquid is an emulsion of oil and water. Coconut milk contains 230 kilocalories and consists of 67.5% water, 23.8% total fat, 5.54% carbohydrates, 2.29% protein and 0.70% ash. During production, coconut milk needs to undergo pretreatment homogeneous high-speed shear. Generally, this type of pretreatment can improve the emulsion stability in coconut milk. This needs to be done because the coconut milk emulsion system is very easily unstable after thawing. Temperature pretreatmentin coconut flesh is the main factor that influences the quality of the coconut milk produced. This study was conducted to analyze changes in the quality of coconut milk after it was done pretreatment storage of coconut flesh before being grated and squeezed into coconut milk and knowing the temperature pretreatment the most appropriate method to obtain the best quality coconut milk by using the Multiple Attribute Zeleny. The research was carried out in stages including the preparation of tools and materials, making coconut milk starting with cleaning the coconut, then giving pretreatment coconut flesh with 3 storage treatments using cold temperatures (6°C ± 2°C) and freezing temperatures (-16°C ± 2°C) stored for 24 hours and room temperature (27°C ± 2°C) without storage time. Then the coconut flesh is grated and the coconut milk is squeezed and continued with testing the quality parameters of coconut milk. The best treatment in the manufacture of coconut milk is to use pretreatment at freezing temperatures (-16°C ± 2°C) which is stored for 24 hours with the quality of coconut milk in the form of 22% yield, 30.59% water content, pH 6.27, and Viscosity 86.70 cP.
Excited-state properties of 6-methoxyflavone in the presence of halide ions in aqueous media
Authors: Fatma Nisha , Pant Sanjay , Pandey Nupur , Mehata Mohan Singh 
Published: June 2023

Abstract
The present work investigated the influence of different halides on the excited state dynamics of 6-methoxyflavone (6MF) in an aqueous solution with steady-state and time-resolved techniques. On successive addition of I− and Br− ions, the fluorescence of 6MF quenched significantly, whereas the respective ions do not change the maximum fluorescence band. Fluorescence of 6MF was quenched 66% by I− ions and 34% by Br− ions. In a pure aqueous medium, both the H-bonded: CT and protonated species of 6MF participate in the quenching of fluorescence. The quenching process was categorized by Stern–Volmer (S–V) and Lehrer equations. Quenching parameters such as KSV, KSV-L and kq were higher for I− ions than Br− ions. The decrease in fluorescence intensity and a reduction in fluorescence lifetime suggested the dynamic nature of quenching by I− ions following the electron transfer mechanism. Fluorescence quenching of 6MF has also been observed in the acidic medium in the presence of different halides. Thus, the study reveals that 6MF is responsive towards I− ions in a wide range of pH, specifically in a purely aqueous environment (pH∼7), hence important for sensing/detection applications.
Real-time correction of chromatic aberration in optical fluorescence microscopy
Authors: López Ana Cayuela , Conesa Pablo , Oña Blanco Ana María , Gómez-Pedrero José Antonio , Sorzano Carlos Oscar S 
Published: June 2023

Abstract
Multi-color fluorescence imaging is a powerful tool for studying the spatial relationships and interactions among sub-cellular structures in biological specimens. However, if improperly corrected, geometrical distortions caused by mechanical drift, refractive index mismatch, or chromatic aberration can lead to lower image resolution. In this paper, we present an extension of the image processing framework of Scipion by integrating a protocol called OFM Corrector, which corrects geometrical distortions in real-time using a B-spline-based elastic continuous registration technique. Our proposal provides a simple strategy to overcome chromatic aberration by digitally re-aligning color channels in multi-color fluorescence microscopy images, even in 3D or time. Our method relies on a geometrical calibration, which we do with fluorescent beads excited by different wavelengths of light and subsequently registered to get the elastic warp as a reference to correct chromatic shift. Our software is freely available with a user-friendly GUI and can be broadly used for various biological imaging problems. The paper presents a valuable tool for researchers working in light microscopy facilities.
Rutile, anatase, brookite and titania thin film from Hubbard corrected and hybrid DFT
Authors: Badalov S V , Bocchini A , Wilhelm R , Kozub A L , Gerstmann U , Schmidt W G 
Published: June 2023

Abstract
As a benchmark, the structural, electronic and optical properties of the three main phases of TiO2 crystals have been calculated using Hubbard U correction and hybrid functional methods in density-functional theory. These calculations are compared concerning the available experimental observations on pristine TiO2 crystals. Modified hybrid functionals, particularly the PBE0 functional with 11.4% fraction of exact exchange, are shown to provide highly accurate atomic structures and also accurate electronic structure data, including optical excitation energies. With DFT + U, accurate optical spectra are also possible, but only if the Hubbard U is applied on the O 2p electrons exclusively. Furthermore, both methods, the 11.4%-PBE0 hybrid functional and the DFT + U
p
scheme have been used to study TiO2 amorphous ultra-thin films, confirming the agreement of the two methods even with respect to small details of the optical spectra. Our results show that the proposed DFT + U
p
methodology is computationally efficient, but still accurate. It can be applied to well-ordered TiO2 polymorphs as well as to amorphous TiO2 and will allow for the calculations of complex titania-based structures.
Flexible layered reduced graphene oxide/aramid nanofiber composite membrane with high thermal conductivity and mechanical properties
Authors: Dong Dandan , Gu Xinwang , Lu Shengjun , Fan Haosen 
Published: June 2023

Abstract
Aramid nanofiber films have shown great potential for high-performance batteries and flexible electronics due to their lightweight and excellent formability. However, aramid nanofibers’ inherent low thermal conductivity severely limits their further applications in high-power electronic devices. Therefore, we attempted to prepare ANF-based composites with excellent thermal conductivity by using reduced graphene oxide (rGO) as a thermally conductive filler for ANF. In this work, we prepared rGO/ANF composite films with horizontal laminar structures by chemical reduction, vacuum-assisted filtration, and hot-press drying. Compared with the pure ANF film (λ, 0.52 W mK−1), the thermal conductivity of the rGO/ANF composite film was greatly improved, and the thermal conductivity increased with increasing rGO content. 50 wt% rGO/ANF composite film achieved an in-plane thermal conductivity of 7.45 W mK−1, 1182.7% higher than the ANF film, and the tensile strength reached 81.7 MPa. Overall, our prepared rGO/ANF composite film exhibits excellent thermal conductivity and good mechanical strength, which helps to explore the potential and development of aramid nanofibres applications in electronic devices.
Study on continuous crystallization and purification of bismuth from Pb-Bi alloy
Authors: Zhou Shengan , Zhang Huan , Li Yifu , Ma Jinping , Yang Bin , Xu Baoqiang 
Published: June 2023

Abstract
The crude bismuth obtained from the smelting of bismuth concentrate and bismuth-containing by-products contains 5%∼20% lead, which needs to be removed during the refining of crude bismuth. Due to the similar physical and chemical properties and metallurgical behavior of lead and bismuth, it is not easy to perform the separation by conventional methods. Although the conventional process of chlorinating crude bismuth to remove lead can meet the requirements of the refining process, the amount of chlorinated slag produced is large, and the safety of chlorine gas is difficult to control, making it difficult to achieve clean production. In this paper, single-factor experiments and semi-industrial experiments for the separation and purification of bismuth from Pb-Bi alloy were carried out by the continuous crystallization method, and the results showed that the bismuth content of Pb-Bi alloy increased from 90.24% to 98.98%, the direct yield of bismuth was 87.37%, the metal recovery rate was 99.84%, and the slag production rate was 0.62%. In comparison with existing processes and studies, the method is low-cost, clean, and efficient, has a wide treatment range, can be operated continuously, and can be easily industrialized and promoted. Theoretically, this method, combined with the process of vacuum distillation to treat Pb-Bi binary alloys with greater than 55.5% bismuth content, results in a 99.99% bismuth product.
Preparation and optoelectronic properties of multi-color high-efficiency CH3NH3Pb(BrxI1-x)3 perovskite light-emitting diodes
Authors: Cai Xiangcheng , Tu Peng , Ai Yansong , He Hongshen , Shen Peng , Zhou Yuanming , Mei Fei 
Published: June 2023

Abstract
Multi-color light-emitting materials are essential lighting and displays. In this study, mixed halide system was applied to precisely tune the bandgap of CH3NH3Pb(Br
x
I1-x
)3, thus regulating the emission wavelength. PEABr was employed to change the phase structure and morphology of CH3NH3Pb(Br
x
I1-x
)3 perovskite thin films and improve the performance of multi-color perovskite light-emitting diodes (PeLEDs). Theoretical simulations through first-principles calculations and experiments demonstrate that multi-color PeLEDs can be achieved by adjusting the ratio of bromine (Br) and iodine (I) atoms in the CH3NH3Pb(Br
x
I1-x
)3 perovskite. The maximum luminance of PEABr-modified green PeLEDs reached 7108 cd m−2, with a maximum current efficiency of 8.25 cd A−1 and a maximum external quantum efficiency (EQE) of 1.62%, which were greatly improved compared to the reference device without PEABr. In addition, the luminance of orange-yellow and red mixed-halide PeLEDs both exceed 100 cd m−2. The results demonstrate that the use of PEABr additive can effectively control the morphology of CH3NH3Pb(Br
x
I1-x
)3 crystals, and high-performance multi-color light-emitting devices can be achieved by combining with mixed halide system. The electroluminescence spectra showed that the emission range of the devices covered the wavelength region of 520–720 nm, demonstrating their good application prospects in the field of multi-color displays.
Integration of CRISPR/Cas with functional nucleic acids as versatile toolbox for non-nucleic acid target diagnostics: a review
Authors: Zhang Wenxian , Chen Zhenzhen , Shi Yang , Wang Jiaqi , Zhang Jingjing 
Published: June 2023

Abstract
Non-nucleic acid targets, consisting primarily of metal ions, organic small molecules and proteins. They act as important biomolecules or cell surface markers, supplying integrated and comprehensive bio-diagnostic information for the early diagnosis and treatment of diseases. Meanwhile, the analysis of non-nucleic acid targets also offers the foundation for individualized medicine and precision therapy. Therefore, a versatile platform for non-nucleic acid targets requires development. Clustered regularly interspaced short palindromic repeats-associated protein (CRISPR/Cas) systems is driving a revolution in medical diagnostics due to high base-resolution and isothermal signal amplification. Nevertheless, the majority of CRISPR/Cas settings reported currently are targeted for nucleic acids, leaving restricted usage to non-nucleic acid targets. This is owing to the lack of suitable signal recognition transduction elements for connecting CRISPR to non-nucleic acid targets. Functional nucleic acids (FNAs), comprising aptamers and nucleic acid enzymes, are of great concern to the biological and medical professions because of their specific target recognition and catalytic properties. As appropriate, functional recognition elements, FNAs can be integrated into CRISPR/Cas systems to exploit the powerful capabilities of both. This review emphasizes the technical tricks of integrating CRISPR/Cas systems and FNAs for non-nucleic acid targeting diagnostic applications. We first offer a general overview and the current state of research in diagnostics for CRISPR/Cas and FNAs, respectively, highlighting strengths and shortcomings. A categorical summary of non-nucleic acid-targeted diagnostics is provided, with a key emphasis on fundamental insights into the versatile non-nucleic acid-targeted diagnostic toolbox. We then review emerging diagnostic strategies based on CRISPR/Cas systems and FNAs that are fast, accurate and efficient in detecting non-nucleic acid targets. Finally, we identify the challenges that remain in this emerging field and look to the future of the field, expanding to the integration of nanomaterials, development of wearable devices and point-of-care testing.
IsoAnalytics: a single-cell proteomics web server
Authors: Palmer Suzette N , Koh Andrew Y , Zhan Xiaowei 
Published: June 2023

Abstract

Motivation
Single-cell proteomics provide unprecedented resolution to examine biological processes. Customized data analysis and facile data visualization are crucial for scientific discovery. Further, user-friendly data analysis and visualization software that is easily accessible for the general scientific community is essential.

Results
We have created a web server, IsoAnalytics, that gives users without computational or bioinformatics background the ability to directly analyze and interactively visualize data obtained from the Isoplexis single cell technology platform. We envision this open-sourced web server will increase research productivity and serve as a free, competitive alternative for single-cell proteomics research.

Availability and implementation
IsoAnalytics is free and available at: https://cdc.biohpc.swmed.edu/isoplexis/ and is implemented in Python, with all major browsers supported. Code for IsoAnalytics is free and available at: https://github.com/zhanxw/Isoplexis_Data_Analysis.

Supplementary information
Supplementary data are available at Bioinformatics Advances online.
Ethical perspectives on surgical video recording for patients, surgeons and society: systematic review
Authors: Walsh Ross , Kearns Emma C , Moynihan Alice , Gerke Sara , Duffourc Mindy , Corrales Compagnucci Marcelo , Minssen Timo , Cahill Ronan A 
Published: June 2023

Abstract

Background
Operating-room audiovisual recording is increasingly proposed, although its ethical implications need elucidation. The aim of this systematic review was to examine the published literature on ethical aspects regarding operating-room recording.

Methods
MEDLINE (via PubMed), Embase, and Cochrane databases were systematically searched for articles describing ethical aspects regarding surgical (both intracorporeal and operating room) recording from database inception to the present (the last search was undertaken in July 2022). Medical subject headings used in the search included ‘operating room’, ‘surgery’, ‘video recording’, ‘black box’, ‘ethics’, ‘consent’, ‘confidentiality’, ‘privacy’, and more. Title, abstract, and full-text screening determined relevance. The quality of studies was assessed using Centre for Evidence-Based Medicine grading and no formal assessment of risk of bias was attempted given the theoretical nature of the data collected.

Results
From 1048 citations, 22 publications met the inclusion criteria, with three more added from their references. There was evident geographical (21 were from North America/Europe) and recency (all published since 2010) bias and an exclusive patient/clinician perspective (25 of 25). The varied methodology (including ten descriptive reviews, seven opinion pieces, five surveys, two case reports, and one RCT) and evidence level (14 level V and 10 level III/IV) prevented meaningful systematic grading/meta-analysis. Publications were narratively analysed for ethical thematic content (mainly education, performance, privacy, consent, and ownership) that was then grouped by the four principles of biomedical ethics of Beauchamp and Childress, accounting for 63 distinct considerations concerning beneficence (22 of 63; 35 per cent), non-maleficence (17 of 63; 27 per cent), justice (14 of 63; 22 per cent), and autonomy (10 of 63; 16 per cent). From this, a set of proposed guidelines on the use of operative data is presented.

Conclusion
For a surgical video to be a truly valuable resource, its potential benefits must be more fully weighed against its potential disadvantages, so that any derived instruments have a solid ethical foundation. Universal, ethical, best-practice guidelines are needed to protect clinicians, patients, and society.