bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global Protein Interactome Mapping in Rice Using Barcode‐Indexed PCR Coupled with HiFi Long‐Read Sequencing
Authors: Liu Xixi , Xia Dandan , Luo Jinjin , Li Mengyuan , Chen Lijuan , Chen Yiting , Huang Jie , Li Yanan , Xu Huayu , Yuan Yang , Cheng Yu , Li Zhiyong , Li Guanghao , Wang Shiyi , Liu Xinyong , Liu Wanning , Zhang Fengyong , Liu Zhichao , Tong Xiaohong , Hou Yuxuan , Wang Yifeng , Ying Jiezheng , ugli Abdullaev Mirtemir Baxodir , Ergashev Mukhammadjon Arabboevich , Zhang Sanqiang , Yuan Wenya , Xue Dawei , Zhang Jianwei , Zhang Jian 
Published: January 2025

AbstractEstablishing the protein–protein interaction network sheds light on functional genomics studies by providing insights from known counterparts. However, the rice interactome has barely been studied due to the lack of massive, reliable, and cost‐effective methodologies. Here, the development of a barcode‐indexed PCR coupled with HiFi long‐read sequencing pipeline (BIP‐seq) is reported for high throughput Protein Protein Interaction (PPI)identification. BIP‐seq is essentially built on the integration of library versus library Y2H mating strategy to facilitate the efficient acquisition of random PPI colonies, semi‐mechanized dual barcode‐indexed yeast colony PCR for the large‐scale indexed amplification of bait and prey cDNAs, and massive pac‐bio sequencing of PCR amplicon pools. It is demonstrated that BIP‐seq could map over 15 000 high‐confidence (≈62.5% could be verified by Bimolecular fluorescence Complementation (BiFC)) rice PPIs within 2 months, outperforming the other reported methods. In addition, the obtained 23 032 rice PPIs, including 22,665 newly identified PPIs, greatly expanded the current rice PPI dataset, provided a comprehensive overview of the rice PPIs networks, and could be a valuable asset in facilitating functional genomics research in rice.
Photochromic Metal‐Organic Frameworks Based on Host‐Guest Strategy and Different Viologen Derivatives for Organic Amines Sensing and Information Anticounterfeiting
Authors: Li Yi‐Dan , Ma Lu‐Fang , Yang Guo‐Ping , Wang Yao‐Yu 
Published: January 2025

AbstractThe encapsulation of viologen derivatives in metal‐organic frameworks (MOFs) to construct host‐guest materials has been widely discussed owing to their distinctive spatial arrangement and physical/chemical properties. Herein, three new photochromic MOFs (NWM‐1–3) have been successfully synthesized by 1,1,2,2‐Tetra(4‐carboxylphenyl)ethylene (H4TCPE) ligand as well as three different viologen derivatives based on host‐guest strategy. Remarkably, NWM‐1–3 exhibit a notable reversible photochromism change from yellow to green under 365 nm UV irradiation. The distance between the electron‐deficient N atom in the viologens and the electron‐rich carboxylate oxygens satisfies the electron transfer (ET) pathway, and thus ET occurs upon irradiation, producing intermolecular viologen radicals. NWM‐1 is able to produce colored responses to different volatile amines by ET and can be recognizable to the naked eye. Differential pulse voltammetry (DPV) analysis and comparative experiments have demonstrated that the host‐guest strategy significantly enhances the electron‐accepting ability of viologens, thereby achieving superior amine sensing performance. NWM‐2 and 3 have been realized in various applications, such as security code, fingerprint, and QR codes for anticounterfeiting. This work provides new host‐guest strategy for designing highly sensitive photochromic materials and color‐tunable luminescent materials, advancing the development of assembled photochromic materials closer to commercialization.
Aluminadichalcogeniranes and Aluminatrichalcogenetanes: Heavier Analogs of Dioxiranes and Trioxetanes
Authors: Zhang Xin , Kong Lingbing , Liu Liu Leo 
Published: January 2025

AbstractDioxiranes and their heavier chalcogen analogs have long been recognized as pivotal reagents and intermediates in synthetic chemistry, while trioxetanes have largely remained theoretical constructs. In this work, we present the synthesis of neutral, isoelectronic aluminum/chalcogen analogs of dioxiranes and trioxetanes, specifically aluminadiselenirane, aluminaditellurirane, aluminatriselenetane, aluminatritelluretane, and a mixed Se/Te analog of aluminatrichalcogenetane. These compounds, featuring strained AlCh2 and AlCh3 ring (Ch=Se, Te), exhibit significant polarization between the aluminum and chalcogen components. Reactivity studies have revealed that both aluminadiselenirane and aluminaditellurirane show pronounced ambiphilic behavior when interacting with proximal substrates, undergoing facile ring‐opening (cyclo)additions. Additionally, the coordination chemistry of aluminatriselenetane with a Lewis acid has been documented. These investigations not only broaden the repertoire of unique main group species but also provide access to heterocyclic structures that present synthetic challenges through conventional methods.
Ion Mobility Mass Spectrometry to Probe Sequences in Supramolecular Copolymers
Authors: Przybylski Cédric , Brocorens Patrick , Xerri Laetitia‐Eiko , Perennes Antoine , Gontard Geoffrey , Lazzaroni Roberto , Raynal Matthieu , Bouteiller Laurent 
Published: January 2025

AbstractThe analysis of the microstructure of supramolecular copolymers is difficult because of their dynamic character. Here, benzene‐1,3,5‐tricarboxamide (BTA) co‐assemblies are analysed by ion mobility – mass spectrometry (IM–MS) to reveal the presence of various sequences. For example, the IM–MS mobilogram for hexamers composed of 4 units from a first monomer and 2 units from a second monomer is a broad distribution due to the presence of 9 possible isomeric sequences, which can be sorted out based on calculated collision cross‐sections. This approach gives unprecedented information on supramolecular copolymer sequences.
Ruthenium‐Catalyzed Deconstruction of Polyolefins: A Strategy to Up‐cycle Waste Polyethylene to Value‐Added Alkene
Authors: Padhi Ganeshdev , Khopade Kishor V. , Moyilla Nageswararao , Rangappa Raghavendrakumar , Chikkali Samir H. , Barsu Nagaraju 
Published: January 2025

AbstractSynthesis of value‐added products from post‐consumer waste polyolefins is fascinating as well as challenging. Here we report ruthenium‐catalyzed up‐cycling of the polyethylene to long‐chain alkene derivatives. The developed methodology mainly involves two steps i.e., dehydrogenation of polyethylene through hydrogen atom transfer and its metathesis using the HG‐II catalyst. The dehydrogenation of polyethylene using ruthenium catalysis derived up to 3.38 %, of double bonds; with 90 % of the recovered polyolefin material. The obtained unsaturated polyethylene was subjected to cross‐metathesis with ethylene using HG‐II catalytic system. This resulted in the synthesis of predominantly dodecene (C12) derivatives, with 58 % selectivity, along with other derivatives of varying chain lengths. The overall reaction produced terminal and internal olefins in the ratio 1:0.8 respectively. The dehydrogenation of polyethylene and its deconstruction was confirmed by NMR spectroscopy, Gel Permeation Chromatography (GPC) and Differential Scanning Calorimetry (DSC). The origin of C12 selectivity has been demonstrated by control experiments. The scope of the methodology was extended to post‐consumer waste polyethylene which gave high conversion to value‐added dodecene derivatives as a major product.
Multi‐Layered Structure as an Efficient Design for Improving Electromagnetic Wave Absorbing Properties of Polypropylene/EVA/Carbon Nanotube Composites
Authors: Sena Adriane , Schmitz Debora P. , Silva Adriana A. , Soares Bluma G. 
Published: January 2025

ABSTRACTFlexible and lightweight conducting polymer composites for application as electromagnetic wave absorbing (EMWA) materials were prepared by a one‐step melt‐blending procedure using a polypropylene/EVA (50:50 wt%) blend filled with carbon nanotube. The co‐continuous structure and the preferential localization of CNT in the EVA phase and at the interface are responsible for the low percolation threshold (0.02 vol%) and a conductivity of 10−3 S m−1 with 1.5 wt% of CNT. Metal‐backed configuration was used for measuring the electromagnetic attenuation in both X‐ (8–12 GHz) and Ku‐band (12–18 GHz). Samples 3 mm thick were compared with three‐layered structures constituted by three layers of 1 mm each. The best EMWA response in terms of minimum reflection loss (RL) (−35.5 dB) and large effective absorption bandwidth (EAB) (6.6 GHz) was observed for the three‐layered system with the appropriate arrangement. The low cost of polymer components and processing conditions, lightweight, and processability, due to the low amount of CNT, make this system a promising candidate for applications in both civilian and military areas as telecommunication and stealth technology.
Self‐Cleaning of Fluorescent Polyester: Construction of Superhydrophobic Coatings by Surface Microsolubility Particle Semi Embedding Technology
Authors: Zheng Xiong , Zhang Xuzhen , Shi Jiaoxue , Yang Zhichao , Li Shuyang , Zhang Yu , Wang Xiuhua 
Published: January 2025

ABSTRACTFluorescent materials are extensively utilized in anti‐counterfeiting and security applications, and surface cleanliness is crucial for preserving their functionality. This study presents a novel hydrophobic fluorescent coating characterized by a morphology in which particles are semi‐embedded and evenly dispersed within the primer. The coating was developed using an innovative method that involves spraying hydrophobic silica onto a microscopically dissolved fluorescent polyethylene terephthalate (PET) primer. The coating demonstrates superior hydrophobicity, with a water contact angle (WCA) of 165.0° ± 5.0° and a sliding angle of 3.0°, as well as an outstanding luminous intensity 541.4 mcd/m2. Due to strong primer and semi‐embedded particle binding, the coating shows good durability. After 80 wear treatment, the hydrophobic properties of the fluorescent coating were largely maintained. After 32 days of exposure to 0.68 W/m2 ultraviolet light, the contact angle decreased from 160.0° to 154.7° (with a sliding angle of 8.0°). In addition, the firmness, transparency, and self‐cleaning function of the coating can be effectively maintained. The coating in this work has solved the inherent problems of functionality, hydrophobicity, and durability in the coating field, and has a wide range of applications including flexible fabrics, road safety field, and building exterior materials.
Provincial Climate Action Index and Its Use for Assessing Dual Carbon Policy of 31 Provinces in China
Authors: Xu Jing , Mei Fengqiao , Lu Chuntian , Zhang Bin , Wang Min 
Published: January 2025

ABSTRACTDual carbon goals ushered in a new era of Chinaʼs climate policies. Provinces play a crucial role in translating climate goals into specific, detailed, and implementable policies, and they are key to Chinese commitments to carbon neutrality. We examine dual carbon policies at the provincial level to better understand the new landscape of local mitigation efforts in China. This research develops a Provincial Climate Action Index based on five policy categories: communication and knowledge sharing, planning guidance, mandatory regulations, funding, and governmental resources. We calculate the index scores of 31 Chinese provinces and identify 3 clusters: leaders, followers, and laggards in dual carbon policy, demonstrating both differences and similarities in provincial‐level actions to achieve climate goals. Provinces such as Shanghai, Beijing, and Anhui are pioneering, nearly half of provinces including Shandong and Shanxi, exhibit medium commitments to the goals, while 10 underperforming provinces such as Qinghai and Xizang lag behind.
Recent Eel Decline in a Large Mediterranean Wetland
Authors: Franch Nati , Capdevila Pol , Fanlo Helena , Queral Josep Maria , Clavero Miguel 
Published: January 2025

ABSTRACTThe European eel (Anguilla anguilla) is a critically endangered and declining species. Information from traditional fisheries and a fish monitoring scheme in the Ebro Delta reflect the widely reported eel decline onset in the late 1970s and also a recent, sharp and ongoing decline of similar magnitude (> 80%). This recent trend arises from both fishery and monitoring data, is solidly described by time‐series analyses and agrees with patterns reported in other areas. Decline drivers could be related to emergent invasions and/or to the exploitation of the already depleted eel stock. There is an urgent need to re‐evaluate eel status and associated management strategies.
Surface Sulfurization and Self‐Reconstruction Strategy for Decorating Carbon Nanofibers to Fabricate Sheet‐Like NiCo2S4 Grown on Ni3S2 Electrode for High‐Energy Density Asymmetric Supercapacitor
Authors: Arun T. , Aravinth K. , Balaji Bhargav P. , Govindasamy Mani 
Published: January 2025

AbstractIn this study, transition metal sulfide‐based binder‐free hybrid electrodes were grown in‐situ on Ni foam using hydrothermal method. However, it still remains a challenge for designing a heterostructure with sufficient electroactive sites to improve electrochemical performance. Herein, effects of CNF@NSNCS on Ni foam binder‐free composites were investigated for developing high‐performance, low‐cost supercapacitors. By avoiding the use of additive binding polymers, the purity of the electrodes was enhanced, resulting in excellent electrochemical behavior. The prepared binder‐free CNF@NSNCS composite electrode exhibited an ultrahigh specific capacitance of 2739 F/g at a current density of 1 A/g, with superior capacitance retention charge‐discharge cycle stability of 100 % over continuous 14,000 cycles at 10 A/g. Furthermore, an asymmetric supercapacitor (ASC) was assembled using CNF@NSNCS binder‐free composites as the positive electrode and Activated carbon (AC) as the negative electrode. The assembled devices demonstrated superior electrochemical performance, delivering a high energy density of 77.5 Wh/kg at a power density of 748.4 W/kg. This work may contribute to advancing the development of low‐cost, high‐performance energy storage applications for the next generation of portable electronic devices.
Toward Suppressing Hydrogen Evolution with Enhanced Performance for Bi‐Modified NaTi2(PO4)3 Anodes in Aqueous Na‐Ion Batteries
Authors: Cao Fengting , Shan Xiaolong , Wu Jiangtao , Chen Yongxin , Zhou Yang , Wang Wenjun , Zeng Chaoliu 
Published: January 2025

AbstractAqueous sodium‐ion batteries (ASIBs) show enormous difficulty to develop appropriate anode materials for their commercialization, mainly owing to the easy occurrence of hydrogen evolution from the decomposition of water at a negative potential with overlapping the operating potential of the anode for the Na+ intercalation/extraction reaction. Here, new anode materials Na1+xBixTi2−x(PO4)3/C (x=0, 0.005, 0.01, 0.02) composites are prepared through introducing Bi elements into NaTi2(PO4)3 (NTP, a promising anode material for ASIBs) with a facile sol‐gel method. Thus, it firstly reports that the Bi doping can contribute to the inhibition of hydrogen evolution via regulation the electrode potential for hydrogen evolution at the anode, also accompanying with excellent electrochemical and charge/discharge performances. The full cell constructed by Na0.44MnO2 as cathode and Bi‐modified NTP as anode, exhibits the better cycling performance with a larger capacity retention of about 80.1 % at 2 C‐rate for 800 cycles and 80.2 % at 10 C‐rate for 1400 cycles in contrast with the pristine one (71.2 %, 56.2 %), respectively. Furthermore, the expansion of the charge cut‐off voltage resulted from the inhibition of hydrogen evolution after Bi doping into NTP can finally increase the discharge capacity and energy density of the modified full cell by 21.8 % and 17.3 %, respectively.
Targeting Lung Cancer With Carvacrol‐Triazole‐Arylidene Hydrazide Hybrids: In Vitro and In Silico Cytotoxicity Assessments
Authors: Çakır Furkan , Ateşoğlu Şeyma , Müderrisoğlu Zeynep Ravza , Demirel Firdevs , Akbaş Fahri , Tokalı Feyzi Sinan , Şenol Halil 
Published: January 2025

ABSTRACTIn this study, a series of 16 arylidene hydrazide derivatives (7a–7p), hybridized with the natural product carvacrol, were successfully synthesized starting from anthranilic acid methyl ester. The cytotoxic effects of these compounds were examined against two different cell lines, A549 and BEAS‐2B. Additionally, in silico studies were conducted to investigate the ligand–protein binding modes and their stabilities. Lastly, the predicted absorption, distribution, metabolism, and excretion (ADME) properties were also explored. The compounds’ structures were confirmed through meticulous NMR and MS spectral analyses. Biological assays indicated notable cytotoxic effects against human lung cancer (A549) and non‐tumorigenic lung epithelial (BEAS‐2B) cell lines, with compounds 7j, 7k, and 7l demonstrating high selectivity indices (SIs) and low IC50 values against A549 cells, signifying potent selective anticancer activity. Molecular docking and molecular dynamics (MD) simulations identified key binding interactions of these compounds with epidermal growth factor receptor (EGFR) and BRAF proteins, emphasizing the importance of residues such as Lys‐745 and Phe‐856 in EGFR and Lys‐483 in BRAF. Stability of these complexes was confirmed through 100 ns MD simulations. ADME analysis revealed favorable pharmacokinetic properties for the prominent compounds, particularly 7k. These results suggest that arylidene hydrazide derivatives, especially 7k, are promising selective anticancer agents with potential for further development.
Defying the Odds: A Case of Successfully Treated Harlequin Ichthyosis in Lebanon
Authors: Hamam Bassel , Saleh Sarah , Yaacoub Miled , Chebbo Houssein , Jalloul Sarah , Karam Karam , Houmani Rima 
Published: January 2025

ABSTRACTHarlequin ichthyosis is a rare skin disorder affecting newborns characterized by a scaly skin, flexed limbs, ectropium, and eclabium. The overall incidence of HI is 1 in 300,000 births, with approximately only 200 cases reported worldwide. Some studies uncovered a TH17 immune skewing in patients with HI, which is also seen in psoriasis. We herein present a case of a newborn found to have harlequin ichthyosis, whom his mother is known to have psoriasis. The baby was treated with topical antibiotics and retinoid creams. The baby then exhibited smoother skin with less scaling and flatter fissures.
Metal‐Free Electrocatalysts for H2O2 Electrosynthesis: From Sites Identification to Electrochemical Advanced Oxidation Process
Authors: Chen Yu , Di Yajing , Zhang Haixing , An Yiming , Miao Jie , Wang Hui , Ji Jing , Li Zhilin , Fujishige Masatsugu , Endo Morinobu , Zhang Zhengping , Wang Feng 
Published: January 2025

AbstractCarbonaceous materials, especially the metal‐free carbons, have attracted widespread attention owing to their risk‐free nature with metal dissolving during the electrocatalysis process, but their further developments are still hindered by missing a suitable scenario on practical applications. Herein, we demonstrate a successful case of using the oxygen‐containing‐groups‐modified carbons for the H2O2 electrosynthesis and the derivative electrochemical advanced oxidation process. The active sites with the more C─O rather than C═O groups are easily obtained by controlling the temperature and time in the wet chemical treatment. Identified by theoretical calculations and electrochemical testing, the modified carbons with the highest ratio of C─O/C═O groups exhibit high activity with above 90% H2O2 selectivity over the entire potential during 2e‐transfer oxygen reduction reaction, attributing to their enlarged charge delocalization. In addition, the corresponding gas diffusion electrodes with the high‐speed and high‐stability H2O2 electrosynthesis (2.78 µg s−1 cm−2 with the above 80% current efficiency) are applied for the electro‐peroxone process on the simulant and practical phenolic wastewater, where the chemical oxygen demand removal reaches above 90%. The long‐term operation in the harsh electrochemical environment for over 200 h also confirms its great potential for practical electrochemical applications.
Cobalt‐based Photocatalysis: From Fundamental Principles to Applications in the Generation of C−X (X=C, O, N, H, Si) Bond
Authors: Pal Adwitiya , De Soumita , Thakur Arunabha 
Published: January 2025

AbstractOver the past few decades, the merger of photocatalysis and transition metal‐based catalysis or self‐photoexcitation of transition metals has emerged as a useful tool in organic transformations. In this context, cobalt‐based systems have attracted significant attention as sustainable alternatives to the widely explored platinum group heavy metals (iridium, rhodium, ruthenium) for photocatalytic chemical transformations. This review encompasses the basic types of cobalt‐based homogeneous photocatalytic systems, their working principles, and the recent developments (2018‐2024) in C−X (X=C, N, O, H, Si) bond formations. Noteworthy to mention that cobalt‐based heterogeneous photocatalysis is beyond the scope of the present review. An elaborate presentation on the mechanistic intricacies of cobalt‐based photocatalysis, without any external photocatalyst, and cobalt‐based dual organophotoredox catalysis have been provided in this comprehensive review, excluding the dual‐metal photoredox catalysis. To the best of our knowledge, this is the only contemporary review encompassing the aforementioned two major types of cobalt‐based photocatalysis, in general synthetic chemistry, covering all types of C−X bond formations spanning a range of the last six years.
Synergistic Effects of Fe3O4/N‐Doped Porous Carbon Nanospheres for Enhanced Oxygen Reduction Reaction
Authors: Li Xiaoge , Liu Huixian , Sun Changxiao , Wang Qin‐Chao , Han Jie 
Published: January 2025

AbstractDesigning transition metal oxide (TMO)/porous carbon composite materials for the oxygen reduction reaction (ORR) is a promising strategy in high‐performance fuel cell technology. In this study, we used the isolation effect and pore‐creating properties of Zn2+ to fabricate a composite material comprising ultrasmall Fe3O4 particles anchored on hierarchically N‐doped porous carbon nanospheres. This material, referred to as CPZ1.0‐Fe0.1, serves as an efficient ORR electrocatalyst in alkaline fuel cells. CPZ1.0‐Fe0.1 exhibits outstanding ORR catalytic activity with a half‐wave potential of 0.86 V in a 0.1 M KOH solution, surpassing that of the Pt/C catalyst (0.82 V). Furthermore, CPZ1.0‐Fe0.1 exhibited excellent stability with minimal current degradation after 18 h of continuous testing. The superior ORR catalytic performance can be attributed to the synergistic effect between the catalytic sites and the high conductivity of porous carbon. The porous carbon nanospheres effectively address the low conductivity of Fe3O4 nanoparticles, while the ultra‐small Fe3O4 nanoparticles anchored on the carbon surface provide efficient catalytic sites for the ORR.
Electrosynthesis of Fluoroalkenes from Alpha‐CF3 and Alpha‐CF2H Benzyl Halides
Authors: He Shiyu , Xu Bo 
Published: January 2025

AbstractWe have developed an efficient synthesis of fluoroalkenes via tandem electrochemical dehalogenation‐elimination protocol. The key step is the generation of carbon anion by electrochemical reductive dehalogenation of alkyl halides. Various gem‐difluoroalkenes and monofluoroalkenes were prepared in moderate to good yields from α‐difluoromethylated/α‐trifluoromethylated benzyl halides.