bluuebunny/crossref_metadata_2025_split huggingface dataset:
SPA-UNet: A liver tumor segmentation network based on fused multi-scale features
Authors: Li Weikun , Jia Maoning , Yang Chen , Lin Zhenyuan , Yu Yuekang , Zhang Wenhui 
Published: September 2023

Abstract
Liver tumor segmentation is a critical part in the diagnosis and treatment of liver cancer. While U-shaped convolutional neural networks (UNets) have made significant strides in medical image segmentation, challenges remain in accurately segmenting tumor boundaries and detecting small tumors, resulting in low segmentation accuracy. To improve the segmentation accuracy of liver tumors, this work proposes space pyramid attention (SPA)-UNet, a novel image segmentation network with an encoder-decoder architecture. SPA-UNet consists of four modules: (1) Spatial pyramid convolution block (SPCB), extracting multi-scale features by fusing three sets of dilated convolutions with different rates. (2) Spatial pyramid pooling block (SPPB), performing downsampling to reduce image size. (3) Upsample module, integrating dense positional and semantic information. (4) Residual attention block (RA-Block), enabling precise tumor localization. The encoder incorporates 5 SPCBs and 4 SPPBs to capture contextual information. The decoder consists of the Upsample module and RA-Block, and finally a segmentation head outputs segmented images of liver and liver tumor. Experiments using the liver tumor segmentation dataset demonstrate that SPA-UNet surpasses the traditional UNet model, achieving a 1.0 and 2.0% improvement in intersection over union indicators for liver and tumors, respectively, along with increased recall rates by 1.2 and 1.8%. These advancements provide a dependable foundation for liver cancer diagnosis and treatment.
Filling in the blank: towards a semiotic account of poetry translation
Authors: Zhou Chunxia , Chen Ningyang 
Published: September 2023

Abstract
Poetry is often seen as the ultimate challenge for a literary translator. Why it is so and how in reality translators manage to accomplish this feat remain to be explored. This article contributes a new way of understanding poetry translation by re-theorizing the practice with reference to the concept of blank-sign. In the light of the blank-sign, we see poetry as a genre rich with meaning-charged blank-signs and poetry translation as a “blank-filling” endeavour to seek relevance for the poem in the target sociocultural context while craftily leaving its overall poetic “blankness” intact for meaningful reading and contemplation. We illustrate this idea with the Spanish translation of two contemporary Chinese poems, with a focus on discussing the challenges with regard to communicating the culture-laden images and the intertextual connections in the original poem. Based on our preliminary findings, we highlight the value of the study of blank-signs in poetry translation and the need for translators to draw insights from cross-linguistic analysis to inform their practice. This semiotic account offers insights into how poetry translation can be alternatively conceptualised and has implications for practitioners involved in poetry and translation.
Polyarylene ether nitrile dielectric films modified by HNTs@PDA hybrids for high-temperature resistant organic electronics field
Authors: Chen Siyi , Yang Shuang , Chen Sisi , Zuo Fang , Wang Pan , Li Ying , You Yong 
Published: September 2023

Abstract
In this work, mussel-inspired surface functionalization of halloysite nanotubes (HNTs) were coated by in situ self-polymerization of polydopamine (PDA) to synthesize core-shell structural composites (HNTs@PDA), and then incorporated into polyarylene ether nitrile (PEN) matrix. Due to the strong adhesion of the PDA modification layer and the formation of hydrogen bonds between the polar nitrile group of PEN and the catechol group of PDA, the dispersion and interfacial compatibility of HNTs@PDA in the PEN matrix are improved. The results show that the dielectric constant of PEN/HNTs@PDA 20 nanocomposites reaches 11.56 (1 kHz), which is 3.2 times that of pure PEN. In addition, after heat treatment, a chemical cross-linking reaction occurred between the PEN matrix to form a cross-linked PEN (CPEN) based nanocomposites, which further improved the thermal stability of the nanocomposites. The results show that the T
g of CPEN/HNTs@PDA 20 nanocomposites reaches 215.5°C, which is 47.7°C higher than that of PEN/HNTs@PDA 20. Moreover, the dielectric constant-temperature coefficient of all CPEN nanocomposites is less than 7 × 10−4°C−1 at the temperature range of 25–180°C. All in all, this work provides a simple and environmentally friendly strategy to adjust the dielectric properties of polymer-based ceramic nanocomposites, which provides a pathway for its application as a dielectric material in the film capacitors field.
Analysis of beef market integration between consumer and producer regions in Indonesia
Authors: Firmansyah  , Maruli Pahantus , Harahap Afriani 
Published: September 2023

Abstract
The research employs secondary data consisting of time series data on beef prices from the consumer regions (Jakarta, Banten, and West Java Provinces) and the producer regions (East Nusa Tenggara, West Nusa Tenggara, Bali, East Java, and Lampung Provinces) obtained from the Center for Information of Strategic Food Prices period January 2018–July 2022. The analytical model utilizes the estimated VAR (vector autoregression)/VECM (vector error correction model). The mean beef price in Indonesia’s producer regions exceeds the normal level (above the reference price), except for East Nusa Tenggara Province, as well as in the consumer regions, which are significantly above the normal level. Beef prices in the producer and consumer regions have a mutual influence in the current and previous periods. The presence of cointegration implies that in the long term, the beef market in the producer regions (East Nusa Tenggara, West Nusa Tenggara, Bali, East Java, and Lampung) is integrated with the consumer regions (Jakarta, Banten, and West Java Provinces) in Indonesia. The most substantial impact of the shock of beef prices in the region of the largest producer is Lampung Province. This research concludes that there is a cointegration of beef prices; in the long term, the beef market in producer regions is integrated with the consumers in Indonesia. Similarly, the beef market will be integrated into producer regions with the consumers in the short term. The VECM is a beef price forecasting model in the producer and consumer regions, which can be considered to have excellent performance.
A review on ceramic waste-based concrete: A step toward sustainable concrete
Authors: Ahmad Jawad , Alattyih Wael , Jebur Yasir Mohammed , Alqurashi Muwaffaq , Garcia-Troncoso Natividad 
Published: September 2023

Abstract
Ceramic waste (CW) has a significant negative environmental influence on the society. However, CW may benefit the environment if it is handled carefully and recycled in concrete production. Recycling CW may lessen the demand for raw materials and waste disposal, thereby preserving natural resources and lowering greenhouse gas emissions. Numerous studies discuss the possibility of CW utilization as concrete ingredients. However, data are spread, making it difficult for the reader or user to assess the benefits and drawbacks of using CW in concrete, which limits its applications. To study the benefits and drawbacks of using CW in concrete and provide the guidelines to the consumer with relevant information, a detailed review is required. Therefore, this study is carried out to collect all relevant updated information from published articles. The major topics of this article include the general history of CW, physical and chemical features, and the influence on concrete parameters including fresh, strength, elevated temperature, and cost benefits. Results indicate that CW decreased concrete flowability and strength. However, with up to 10% substitution, the results are satisfactory, and concrete can be used for a normal-strength structure. Furthermore, the review also identifies the research gaps that need to be investigated.
Intermittent Collusive Agreements: Antitrust Policy and Business Cycles
Authors: Dargaud Emilie , Jacques Armel 
Published: September 2023

Abstract
In this article we study collusive strategies and the optimal level of fines when firms face random demand fluctuations. Collusive firms can choose to alternate collusive periods with more competitive periods: such an intermittent strategy can be implemented particularly if demand variability is high. Firms then set competitive prices during recessions to cancel the risk of cartel detection and keep the ability to cartelize for the future. If the maximum fine is too low to fully deter cartels, the antitrust authority can influence the choice of collusive agreement by varying the level of fines according to demand states. If the demand is highly variable, the antitrust authority may induce firms to collude in all demand states (by decreasing the fine during recessions), in order to detect and break up cartels more easily. On the other hand, if the demand variability is low the optimal policy may be to reduce the fine when demand is high.
An Analysis of the Relationship between Cognitive Flexibility and Anger in Geriatric Individuals
Authors: Harmancı Pınar , İçel Sema 
Published: September 2023

Introduction. In geriatrics, cognitive flexibility, which is known to be effective in individuals’ being patient with events, is the ability to activate one’s cognition in the face of sudden unexpected situations by processing. Being cognitively positive or negative affects geriatric individuals’ cognitive flexibility levels. It is important to examine the anger levels of geriatric individuals in the evaluation of their cognitive flexibility.
Aim. This study aims to examine the relationship between cognitive flexibility and anger in geriatric individuals.
Material and Methods. The current study was held in a Nursing Home in Central Turkey. The purposive sampling method was used in sample selection. The present research is designed as a descriptive study.
Results. There are statistically significant and negative correlations between the CFS and State-Anger, Anger/In, and Anger/Out. Furthermore, there is a statistically significant and positive correlation between the CFS and Anger/Control.
Conclusions. It is seen that the daily forgetfulness level and the mean scores of Anger/In and Anger/Out, which are state-anger and trait-anger styles, increased, while the mean scores of Anger/Control and Cognitive Flexibility decreased. (JNNN 2023;12(1):9–16)
The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice
Authors: Kawabata Yuko , Takai Shingo , Sanematsu Keisuke , Yoshida Ryusuke , Kawabata Fuminori , Shigemura Noriatsu 
Published: September 2023

AbstractDrug-induced taste disorders reduce quality of life, but little is known about the molecular mechanisms by which drugs induce taste disturbances. In this study, we investigated the short-term and long-term effects of the antiarrhythmic drug flecainide, which is known to cause taste dysfunction. Analyses of behavioral responses (licking tests) revealed that mice given a single intraperitoneal injection of flecainide exhibited a significant reduction in preference for a sour tastant (HCl) but not for other taste solutions (NaCl, quinine, sucrose, KCl and monopotassium glutamate) when compared with controls. Mice administered a single dose of flecainide also had significantly higher taste nerve responses to HCl but not to other taste solutions. Compared with controls, mice administered flecainide once-daily for 30 d showed a reduced preference for HCl without any changes in the behavioral responses to other taste solutions. The electrophysiological experiments using HEK293T cells transiently expressing otopetrin-1 (Otop1; the mouse sour taste receptor) showed that flecainide did not alter the responses to HCl. Taken together, our results suggest that flecainide specifically enhances the response to HCl in mice during short-term and long-term administration. Although further studies will be needed to elucidate the molecular mechanisms, these findings provide new insights into the pathophysiology of drug-induced taste disorders.
Similarities and Distinctions between Cortical Neural Substrates That Underlie Generation of Malevolent Creative Ideas
Authors: Qiao Xinuo , Lu Kelong , Yun Qiang , Hao Ning 
Published: September 2023

AbstractCreativity can be driven by negative intentions, and this is called malevolent creativity (MC). It is a type of creativity that serves antisocial purposes and deliberately leads to harmful or immoral results. A possible classification indicates that there are three kinds of MC in daily life: hurting people, lying, and playing tricks. This study aimed to explore similar and distinct neural substrates underlying these different kinds of MC idea generation. The participants were asked to perform different MC tasks, and their neural responses were recorded using a functional near-infrared spectroscopy device. The findings revealed that most regions within the prefrontal and temporal lobes [e.g., the right dorsolateral prefrontal cortex (rDLPFC), and right angular gyrus] were involved in the three MC tasks. However, the right frontopolar cortex (rFPC) was more activated and less coupled with the rDLPFC and right precuneus during the lying task than during the other tasks. Thus, rFPC may play an important role in constructing novel lies. In the lying task, individuals were more selfish and less compassionate. In the playing tricks and hurting people tasks, there was less neural coupling between the rDLPFC and the left inferior frontal gyrus/right inferior parietal lobule than that in the lying task. This may imply that selfish motivation is released when individuals try to ignore victims’ distress or generate aggressive tricks in hurting people or playing tricks tasks. These findings indicate that the three kinds of MC idea generation involve common cortical regions related to creative idea generation and moral judgment, whereas differences in cortical responses exist because of their unique features.
Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease
Authors: Mödl Bernadette , Awad Monira , Zwolanek Daniela , Scharf Irene , Schwertner Katharina , Milovanovic Danijela , Moser Doris , Schmidt Katy , Pjevac Petra , Hausmann Bela , Krauß Dana , Mohr Thomas , Svinka Jasmin , Kenner Lukas , Casanova Emilio , Timelthaler Gerald , Sibilia Maria , Krieger Sigurd , Eferl Robert 
Published: September 2023

AbstractIntestinal epithelial cells are covered by the brush border, which consists of densely packed microvilli. The Intermicrovillar Adhesion Complex (IMAC) links the microvilli and is required for proper brush border organization. Whether microvillus crosslinking is involved in the intestinal barrier function or colitis is currently unknown. We investigate the role of microvillus crosslinking in colitis in mice with deletion of the IMAC component CDHR5. Electron microscopy shows pronounced brush border defects in CDHR5‐deficient mice. The defects result in severe mucosal damage after exposure to the colitis‐inducing agent DSS. DSS increases the permeability of the mucus layer and brings bacteria in direct contact with the disorganized brush border of CDHR5‐deficient mice. This correlates with bacterial invasion into the epithelial cell layer which precedes epithelial apoptosis and inflammation. Single‐cell RNA sequencing data of patients with ulcerative colitis reveals downregulation of CDHR5 in enterocytes of diseased areas. Our results provide experimental evidence that a combination of microvillus crosslinking defects with increased permeability of the mucus layer sensitizes to inflammatory bowel disease.
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse
Authors: Zhu Guang‐Jie , Huang Yuhang , Zhang Linqing , Yan Keji , Qiu Cui , He Yihan , Liu Qing , Zhu Chengwen , Morín Matías , Moreno‐Pelayo Miguel Ángel , Zhu Min‐Sheng , Cao Xin , Zhou Han , Qian Xiaoyun , Xu Zhigang , Chen Jie , Gao Xia , Wan Guoqiang 
Published: September 2023

AbstractCingulin (CGN) is a cytoskeleton‐associated protein localized at the apical junctions of epithelial cells. CGN interacts with major cytoskeletal filaments and regulates RhoA activity. However, physiological roles of CGN in development and human diseases are currently unknown. Here, we report a multi‐generation family presenting with autosomal dominant non‐syndromic hearing loss (ADNSHL) that co‐segregates with a CGN heterozygous truncating variant, c.3330delG (p.Leu1110Leufs*17). CGN is normally expressed at the apical cell junctions of the organ of Corti, with enriched localization at hair cell cuticular plates and circumferential belts. In mice, the putative disease‐causing mutation results in reduced expression and abnormal subcellular localization of the CGN protein, abolishes its actin polymerization activity, and impairs the normal morphology of hair cell cuticular plates and hair bundles. Hair cell‐specific Cgn knockout leads to high‐frequency hearing loss. Importantly, Cgn mutation knockin mice display noise‐sensitive, progressive hearing loss and outer hair cell degeneration. In summary, we identify CGN c.3330delG as a pathogenic variant for ADNSHL and reveal essential roles of CGN in the maintenance of cochlear hair cell structures and auditory function.
Sterile triggers drive joint inflammation in TNF‐ and IL‐1β‐dependent mouse arthritis models
Authors: Thiran Alexandra , Petta Ioanna , Blancke Gillian , Thorp Marie , Planckaert Guillaume , Jans Maude , Andries Vanessa , Barbry Korneel , Gilis Elisabeth , Coudenys Julie , Hochepied Tino , Vanhove Christian , Gracey Eric , Dumas Emilie , Manuelo Teddy , Josipovic Ivan , van Loo Geert , Elewaut Dirk , Vereecke Lars 
Published: September 2023

AbstractArthritis is the most common extra‐intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shared disease etiology, commonly termed “the gut‐joint‐axis.” The clinical association between gut and joint inflammation is further supported by the success of common therapeutic strategies and microbiota dysbiosis in both conditions. Most data, however, support a correlative relationship between gut and joint inflammation, while causative evidence is lacking. Using two independent transgenic mouse arthritis models, either TNF‐ or IL‐1β dependent, we demonstrate that arthritis develops independently of the microbiota and intestinal inflammation, since both lines develop full‐blown articular inflammation under germ‐free conditions. In contrast, TNF‐driven gut inflammation is fully rescued in germ‐free conditions, indicating that the microbiota is driving TNF‐induced gut inflammation. Together, our study demonstrates that although common inflammatory pathways may drive both gut and joint inflammation, the molecular triggers initiating such pathways are distinct in these tissues.
The Influence of The Teachers' Reading Habit On Their Teaching Practice: A Narrative Inquiry
Authors: Wijayanti Etri , Mujiyanto Yan , Pratama Hendi 
Published: September 2023

We consider the substantial relationship between teachers' reading habits and teaching practices in the Indonesian context. This issue has piqued the interest of research. Therefore, this study investigates how teachers' reading habits influence their teaching practice. This study employs narrative inquiry by Clandinin and Connelly (2000) as a qualitative research design, allowing us to collect rich data through the unique stories of the participants. This study involves three Indonesian English teachers at one of the vocational high schools in Indonesia, namely SMK Negeri 1 Pringapus. Specifically, this study uses a narrative inquiry framework by Clandinin and Conelly (2002). We collected the data through observation, questionnaires, interviews Creswell (2012); transcribing, and coding based on Bailey (2008). Additionally, to obtain trustworthiness, we use the theory of Guba and Lincoln (1982). The findings show that teachers' reading habits have vital roles in their teaching practice. The findings also clearly demonstrate a solid and lasting relationship between teachers' reading habits and teaching practice. This study suggests that educators, in particular, should improve reading habits both for professional needs as teachers and personal needs. It is also necessary to continue to improve the quality of teaching practice by strengthening reading habits.
Key Words: teachers' reading habit, narrative inquiry, teaching practice
El Desarrollo del Liderazgo Educativo. Evidencias de un Estudio de Historias de Vida
Authors: Rodríguez Espinoza Simón , Cárdenas Cofre Cristian , Campos Vergara Fabián 
Published: September 2023

La evidencia da cuenta que las acciones de los líderes es una importante variable que incide en la mejora del trabajo docente y de las organizaciones educativas. Sin embargo, no se ha escrito mucho sobre la adquisición, progresión y refinamiento de los conocimientos y habilidades profesionales de directores/as. Se desarrolla un método cualitativo, utilizando la técnica historia de vida. Se reconstruyeron las trayectorias formativas en 4 etapas: formación secundaria, formación inicial (educación superior), formación continua previa al ejercicio como director/a, y formación continua en el cargo. Respecto de las instancias de formación, se identifican instancias formales e informales. Se identifican los siguientes aprendizajes en las trayectorias formativas: relativos a capacidades y habilidades de comunicación y relaciones interpersonales positivas, rol docente, enseñanza – aprendizaje, y administración y gestión. Se relevan instancias principalmente informales, con metodologías de observación de modelos, con un especial énfasis en la “observación en y de la acción”. A su vez, se presentan de manera continua prácticas de debates, y el ejercicio de roles de coordinación y ejecución de proyectos reales. Respecto de trayectorias de formación, las categorías de aprendizaje presentan una creciente complejización a medida que se avanza en las etapas de formación. Respecto de las instancias y métodos, este estudio releva la participación en grupos, con diversidad de profesionales y/o de experiencia laboral, ocupando diversos roles. A su vez, se identifican los aprendizajes en contextos laborales, con el desarrollo de trabajos y proyectos grupales, y con evaluaciones y seguimiento periódicos.