bluuebunny/crossref_metadata_2025_split huggingface dataset:
Big data analysis of endovascular treatment of intracranial aneurysms: a bibliometric analysis of the top 100 most cited articles
Authors: Zhang Shuai , Liu Dong , Wang Jiao , Lv Ming 
Published: December 2022

Abstract
Background The impact of a literature report on a particular subject can be measured by its number of citations.
Objective The purpose of this study was to evaluate the characteristics of the literature reports in the field of endovascular treatment of intracranial aneurysms (IAs) by analyzing the top 100 most cited articles. It should be noted that the focus of this study is to describe the bibliometric characteristics.
Methods This bibliometric analysis dedicated only to endovascular treatment of IAs in our study. We searched the top 100 most cited articles in the field of endovascular treatment of IAs using the search tool of the Web of Science (WOS). We evaluated the characteristics of these high-impact publications, including publication year, category, journal, author's country, etc.
Results The top 100 most cited articles were cited 281.3 times, on average. The United States has published the most articles every year compared with other countries. These highly cited articles are mostly published in the Journal of Neurosurgery. Eighty-six of the top 100 most cited articles were clinical studies.
Conclusion The bibliometric analysis provides insight over the development and the growing trend in endovascular treatment of IAs. This study can help researchers better understand the global overview of this field, and it also provides leads about promising areas of future research and potential collaborations.
Botulism in the Brazilian Amazon: a life-threatening disease in a neglected population
Authors: Oliveira Louise Makarem , Gonçalves Daniel Buzaglo , Cabral Lucas de Cristo Rojas , Bernardino Marília Rosa Abtibol , Feitoza Pablo Vinícius Silveira 
Published: December 2022

Abstract
Background Botulism is a rare and potentially fatal neuroparalytic syndrome caused by the gram-positive anaerobe spore-forming bacterium Clostridium botulinum. The microorganism produces a neurotoxin that inhibits the presynaptic release of acetylcholine at the neuromuscular junction, clinically leading to a myasthenic syndrome.
Objective To describe the recent outbreak of botulism cases and its demographic, clinical, and laboratory characteristics.
Methods We report 4 patients with botulism in the recent outbreak occurred between 2017 and 2019 in the state of Amazon.
Results Out of four patients with botulism, three contracted it from eating contaminated food and one had wound botulism. We emphasize the excellent clinical outcome of the different disease presentations in our case series.
Conclusion The temporal proximity of these reports may suggest a new rise in the number of cases in the upcoming years. A possible hypothesis is that the rarity of the disease decreased the awareness regarding the primary prevention or even a diagnosis by an untrained physician.
The antiinflammatory and electrophysiological effects of fingolimod on penicillin-induced rats
Authors: Türel Canan Akünal , Çelik Hümeyra , Torun İbrahim Ethem , Çetinkaya Ayhan , Türel İdris 
Published: December 2022

Abstract
Background The fact that inflammation triggers epileptic seizures brings to mind the antiepileptic properties of anti-inflammatory drugs.
Objective To investigate the electrophysiological and anti-inflammatory effects of fingolimod on an experimental penicillin-induced acute epileptic seizure model in rats.
Methods Thirty-two male Wistar rats were divided into four groups: control (penicillin), positive control (penicillin + diazepam [5 mg/kg]), drug (penicillin + fingolimod [0.3 mg/kg]) and synergy group (penicillin + diazepam + fingolimod). The animals were anesthetized with urethane, and epileptiform activity was induced by intracortical injection of penicillin (500,000 IU). After electrophysiological recording for 125 minutes, IL-1β, TNF-α, and IL-6 were evaluated by ELISA in the serum of sacrificed animals.
Results During the experiment, animal deaths occurred in the synergy group due to the synergistic negative chronotropic effect of diazepam and fingolimod. Although not statistically significant, fingolimod caused a slight decrease in spike-wave activity and spike amplitudes in the acute seizure model induced by penicillin (p > 0.05). Fingolimod decreased serum IL-1β (p < 0.05); fingolimod and diazepam together reduced IL-6 (p < 0.05), but no change was observed in serum TNF-α values.
Conclusion Even in acute use, the spike-wave and amplitude values of fingolimod decrease with diazepam, anticonvulsant and anti-inflammatory effects of fingolimod will be more prominent in chronic applications and central tissue evaluations. In addition, concomitant use of fingolimod and diazepam is considered to be contraindicated due to the synergistic negative inotropic effect.
Comparison of the Effects of GMCSF-Containing and Traditional Culture Media on Embryo Development and Pregnancy Success Rates
Authors: Adanacıoglu Fatih , Çetin Çağlar , Tokat Gozde , Adanacıoglu Durdane , Karasu Ayse Filiz Gokmen , Çetin Mehmet Turan 
Published: December 2022

Abstract
Objective The use of granulocyte macrophage colony-stimulating factor (GM-CSF)-containing medium, which is a commercial medium that is used for cultivation of embryos in in vitro fertilization (IVF) treatments, has been suggested to increase the efficiency of this procedure in patients with previous multiple unsuccessful attempts. In this retrospective study, we analyzed GM-CSF-containing embryo culture media compared with traditional culture media in terms of development of embryos, pregnancy, and ongoing pregnancy success and live birth rates.
Methods This is a prospective case control study conducted in a single center. A total of 131 unexplained infertility patients were included in the study. A cohort of 69 patients whose embryos were cultured in GM-CSF-containing medium and a control group of 62 age-matched patients whose embryos were cultured in conventional Sage One Step medium were included in the study. The major study outcomes were achievement of pregnancy and ongoing pregnancy rate at 12 weeks of gestation.
Results The pregnancy and ongoing pregnancy rates of the patients whose embryos were cultured in GM-CSF-containing medium were 39.13% and 36.23%, respectively. These were higher than the rates of the control group, which were 30.65% and 29.03%, respectively, although this difference was not statistically significant. In addition, the 5th-day embryo transfer percentage in the GM-CSF group was higher than in the control group (34.78% versus 27.4%).
Conclusion The main findings of our study were that there was no difference between the GM-CSF-enhanced medium and the control group in terms of our major study outcomes. However, blastomere inequality rate and embryo fragmentation rates were lower in the GM-CSF group.
Randomized Clinical Trial Comparing Quadratus Lumborum Block and Intrathecal Morphine for Postcesarean Analgesia
Authors: Araújo Karoline Moura de , Ferraro Leonardo Henrique Cunha , Sun Sue Yasaki , Mattar Rosiane 
Published: December 2022

Abstract
Objective To compare the efficacy of quadratus lumborum (QL) block and intrathecal morphine (M) for postcesarean delivery analgesia.
Methods Thirty-one pregnant women with ≥ 37 weeks of gestation submitted to elective cesarean section were included in the study. They were randomly allocated to either the QL group (12.5 mg 0.5% bupivacaine for spinal anesthesia and 0.3 ml/kg 0.2% bupivacaine for QL block) or the M group (12.5 mg bupivacaine 0.5% and 100 mcg of morphine in spinal anesthesia). The visual analog scale of pain, consumption of morphine and tramadol for pain relief in 48 hours, and side effects were recorded.
Results Median pain score and/or pain variation were higher in the morphine group than in the QL group (p = 0.02). There was no significant difference in the consumption of morphine or tramadol between groups over time. Side effects such as pruritus, nausea, and vomiting were observed only in the morphine group.
Conclusion Quadratus lumborum block and intrathecal morphine are effective for analgesia after cesarean section. Patients undergoing QL block had lower postoperative pain scores without the undesirable side effects of opioids such as nausea, vomiting, and pruritus.
Provider Response to a Venous Thromboembolism Risk Assessment and Prophylaxis Ordering Tool: Observational Study
Authors: Khan Sundas , King D'Arcy , Osmani Soheb , Harte Owen , Solomon Jeffrey , Niranjan Kunti , Rosenberg David J. 
Published: December 2022

Abstract
Objectives Our health system launched an initiative to regulate venous thromboembolism (VTE) risk assessment and prophylaxis with electronically embedded risk assessment models based on validated clinical prediction rules. Prior to system-wide implementation, usability testing was conducted on the VTE clinical decision support system (CDSS) to assess provider perceptions, facilitate adoption, and usage of the tool. The objective of this study was to conduct usability testing with end users on the CDSS' risk assessment model and prophylaxis ordering components.
Methods This laboratory usability testing study was conducted with 24 health care providers. Participants were given two case scenarios that mirrored real-world scenarios to assess likelihood of use and adoption. During each case scenario, participants engaged in a think-aloud session, verbalizing their decision-making process while interacting with the tool. Following each case scenario, participants completed the System Usability Scale (SUS) and a posttask interview. Participants' comments and interactions with the VTE CDSS were placed into coding categories and analyzed for generalizable themes by three independent coders.
Results Of the 24 participants, 50% were female and the mean age of all participants was 32.76 years. The average SUS across the different services lines was 72.39 (C grade). Each participant's comments were grouped into three overarching themes: functionality, visibility/navigation, and content. Comments included personalizing workflow for each service line, minimizing the number of clicks, clearly defining risk models, including background on risk scores, and providing treatment guidelines for order sets.
Conclusion An important step toward providing quality health care to patients at risk of developing a VTE event is providing user-friendly tools to providers. Following usability testing, our study revealed opportunities to positively impact provider behavior and acceptance. The rigor and breadth of this usability testing study and adoption of the optimizations should increase provider adoption and retention of the VTE CDSS.
Maternal Mercury Exposure and Hypertensive Disorders of Pregnancy: A Systematic Review
Authors: Dantas Aline de Oliveira , Castro Thiania dos Santos da Silva de , Câmara Volney de Magalhães , Santos Aline de Souza Espindola , Asmus Carmen Ildes Rodrigues Froes , Vianna Angelica dos Santos 
Published: December 2022

Abstract
Objective The present review aimed to synthesize the evidence regarding mercury (Hg) exposure and hypertensive disorders of pregnancy (HDP).
Data Sources The PubMed, BVS/LILACS, SciELO and UFRJ's Pantheon Digital Library databases were systematically searched through June 2021.
Study Selection Observational analytical articles, written in English, Spanish, or Portuguese, without time restriction.
Data Collection We followed the PICOS strategy, and the methodological quality was assessed using the Downs and Black checklist.
Data Synthesis We retrieved 77 articles, of which 6 met the review criteria. They comprised 4,848 participants, of which 809 (16.7%) had HDP and 4,724 (97.4%) were environmentally exposed to Hg (fish consumption and dental amalgam). Mercury biomarkers evaluated were blood (four studies) and urine (two studies). Two studies found a positive association between Hg and HDP in the group with more exposure, and the other four did not present it. The quality assessment revealed three satisfactory and three good-rated studies (mean: 19.3 ± 1.6 out 28 points). The absence or no proper adjustment for negative confounding factor, such as fish consumption, was observed in five studies.
Conclusion We retrieved only six studies, although Hg is a widespread toxic metal and pregnancy is a period of heightened susceptibility to environmental threats and cardiovascular risk. Overall, our review showed mixed results, with two studies reporting a positive association in the group with more exposure. However, due to the importance of the subject, additional studies are needed to elucidate the effects of Hg on HDP, with particular attention to adjusting negative confounding.
Managing the Messy Mathematics
Authors: Williams Darren L. , Jackson Victoria S. 
Published: December 2022

Simulation yields understanding. If you can simulate a phenomenon in nature, then perhaps you understand the parts that make up the natural phenomenon. This chapter begins with the phenomenon of the blackbody emission spectrum represented by Planck's Distribution Law. This is the data. We simulate this spectrum using a one-dimensional particle in a box system. The simulation matches the general shape of the Planck distribution. The rest of the chapter takes you progressively deeper into the equations that produce the wavelengths of the transitions, the spectral line shapes, the temperature dependence of the spectrum, and the intensity of the transitions. These equations all depend upon the wave functions and the interactions of the wave functions with light. This chapter provides a roadmap for spectroscopy by tracing the path from the data to the wave function. All the equations are presented in this chapter, but they are solved in the next three chapters. After reading the Analytical Calculus Chaps. (2–5), you will understand in detail that everything in the spectrum depends upon the wave function, the boundary conditions, the mass of the particle, and the temperature.
When confronted with the first application of wave mechanics to the hydrogen atom, Schrödinger exclaimed to his colleague Wilhelm Wein, “If only I knew more mathematics!” (1) This chapter provides a roadmap to help you manage the messy mathematics showing the equations that connect absorption, emission, and scattering spectra to the quantum world through wave mechanics.
These equations are solved using two independent approaches—analytical calculus and group theory. A third approach using numerical calculus is developed in a second book which teaches the practical skill of simulating spectroscopic phenomena. The ultimate goal of the text is to produce the math required to compute realistic simulated spectra of the particle in a box and particle on a ring systems. The mathematical results have been implemented in a spectral simulation spreadsheet to illustrate the success of quantum mechanical theory and to develop in the reader an intuition of everything that feeds into the features of the spectra of real molecular systems.
The analytical approach is useful for computing the general solutions for spectroscopic transition intensities and energies. From these equations, one can draw stick spectra similar to Schrödinger's (Fig. 1.2) and can readily see the dependence upon mass, temperature, and system size. Inclusion of the line-shape functions allows the reader to experiment with the influence of spectral resolution in the spectral simulations.
The group theoretical approach allows a Post-It-Note® computation of the selection rules, which is sufficient in most cases for the assignment of quantum numbers to the experimental spectral transitions.
Interfacial variation in HfO2-based resistive switching devices with titanium electrodes under asymmetric bias operation
Authors: Zhou Kuan-Ju , Chen Min-Chen , Chang Ting-Chang , Lin Shih-Kai , Wang Yu-Bo , Zhang Yong-Ci , Yen Po-Yu , Shao Kui-You , Huang Hui-Chun , Huang Jen-Wei , Sze Simon M 
Published: December 2022

Abstract
Resistance fluctuations are persistent and critical issues in memory device applications. In recent years, several investigations have been conducted to unravel such fluctuations to further improve the retention and endurance of random resistance access memory (RRAM). Elucidating the switching mechanisms and causes of delamination at the insulator/electrode interface during practical bias operations is thus essential for improving RRAM performance. In this work, we first investigated the changes at the Ti/HfO2 interface in the Ti/HfO2/TiN RRAM device for consecutive bias operations. After the negative forming process and the following asymmetric bias operation conditions, the electrical output of the device decreased as a result of abnormal current degradation during iterative set/reset operations, during which the current high-resistance state (HRS) and low-resistance state (LRS) appeared to decrease. Transmission electron microscopy images and energy dispersive spectroscopy point data indicated that titanium oxides are formed at the Ti/HfO2 interface after asymmetric bias operation compared to the Ti/HfO2 interface of the pristine device, which provides direct evidence for validating the current degradation. In addition, to verify the influence of the electric fields on the devices during bias operation, we modulated the rising time of the set pulse triangle wavefront to further verify that the formation of TiO
x
depends on the amplitude of the electric field. Finally, the fitted current results indicate that the conduction mechanism after asymmetric bias operation in HRS and LRS is hopping conduction. Accordingly, a plausible physical model for bias operation in RRAM devices is proposed.
Resolution effects on spectral analysis of low alloy steel by laser-induced breakdown spectroscopy
Authors: Shen Sijie , Chen Peng , Luo Han , Wang Zhenzhen , Yan Junjie , Deguchi Yoshihiro 
Published: December 2022

Abstract
The influence of resolution on spectral analysis is of great significance to improve the measurement accuracy of laser-induced breakdown spectroscopy (LIBS). In this study, low alloy steel samples were measured at different resolutions using a dual-channel spectrometer simultaneously to determine the plasma characteristics. The diffraction efficiency of the grating was different at different resolutions, which led to different spectral intensities measured at different resolutions. The resolution affected the LIBS spectral analysis. For plasma spectral analysis, the experimental results showed that the Boltzmann plot method was suitable for calculating the plasma temperature using the low-resolution spectra with 0.076 nm/pixel. Based on the high-resolution spectra with 0.01 nm/pixel, the Boltzmann double lines method was applied to calculate the plasma temperature, and the analysis line was I
FeI395.668/I
FeI400.524. Due to the influence of instrument broadening, Stark broadening could only be used to characterize the electron density using the high-resolution spectra. For quantitative analysis in LIBS spectral analysis, support vector machine regression (SVR) with different inputs was used to quantitatively analyze the Mn content in the low alloy steel. The prediction accuracy of the low-resolution spectra was poor compared to the high-resolution spectra. When the input was the target spectral intensities and the plasma state, the fitting accuracy and prediction accuracy were improved. This showed that SVR combined with the plasma state was an effective method to improve the accuracy of the quantitative analysis of Mn content in low alloy steel by LIBS.
The magnetic field driven superconductor–metal transition in disordered hole-overdoped cuprates
Authors: Johnsen Lina G 
Published: December 2022

Abstract
By solving the Bogoliubov–de Gennes equations for a d-wave superconductor, we explore how the interplay between disorder and the orbital depairing of an external magnetic field influences the superconductor–metal transition of the hole-overdoped cuprates. For highly disordered systems, we find granular Cooper paring to persist above the critical field where the superfluid stiffness goes to zero. We also show that because the vortices are attracted to regions where the superconducting pairing is already weak, the Caroli–de Gennes–Matricon zero-bias peak in the local density of states at the vortex cores disappears already at moderate disorder.
Effects of spatial quantization and Rabi-shifted resonances in single and double excitation of quantum wells and wires induced by few-photon optical field
Authors: Tikhonova Olga V , Vasil’ev Andrey N 
Published: December 2022

Abstract
We develop a fully quantum theoretical approach which describes the dynamics of Frenkel excitons and bi-excitons induced by few photon quantum light in a quantum well or wire (atomic chain) of finite lateral size. The excitation process is found to consist in the Rabi-like oscillations between the collective symmetric states characterized by discrete energy levels. At the same time, the enhanced excitation of high-lying free exciton states being in resonance with these ‘dressed’ polariton eigenstates is revealed. This found new effect is referred to as the formation of Rabi-shifted resonances and appears to be the most important and new feature established for the excitation of 1D and 2D nanostructures with final lateral size. The found new physics changes dramatically the conventional concepts of exciton formation and play an important role for the development of nanoelectronics and quantum information protocols involving manifold excitations in nanosystems.
Energy distribution of inelastic gas in a box is dominated by a power law—a derivation in the framework of sample space reducing processes
Authors: Thurner Stefan , Korbel Jan , Hanel Rudolf 
Published: December 2022

Abstract
We use the framework of sample space reducing (SSR) processes as an alternative to Boltzmann equation based approaches to derive the energy and velocity distribution functions of an inelastic gas in a box as an example of a dissipative, driven system. SSR processes do not assume molecular chaos and are characterized by a specific type of eigenvalue equation whose solutions represent stationary distribution functions. The equations incorporate the geometry of inelastic collisions and a driving mechanism in a transparent way. Energy is injected by boosting particles that hit the walls of the container to high energies. The numerical solution of the resulting equations yields approximate power laws over the entire energy region. The exponents decrease with the driving rate from about 2 to below 1.5 and depend on the coefficient of restitution. Results are confirmed with a molecular dynamics simulation in 3D with the same driving mechanism. The numerical solution of the resulting equations yields approximate power laws over the entire energy region. Deviations depend on the details of driving, density, and container.
Galvanomagnetic properties of a thin metal film considering dimensional quantization and diffuse surface scattering of electrons
Authors: Kuznetsova I A , Romanov D N , Savenko O V 
Published: December 2022

Abstract
The Expressions for the transverse magnetoresistance coefficient and the Hall coefficient of a film are analytically obtained and analyzed. Quantum dimensional effect is taken into account, but Landau levels are not considered. The film zone structure is spherically symmetric and obeys the parabolic law. Galvanomagnetic coefficients are calculated from the Liouville (von Neumann) equation taking into account diffuse boundary conditions for the distribution function.