bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is massage a legitimate part of nursing care? A qualitative study
Authors: Da Rocha Rodrigues Gora , Anex Adrien , Boegli Monique , Bollondi Pauly Catherine , Curtin François , Luthy Christophe , Desmeules Jules , Cedraschi Christine 
Published: February 2023

Introduction
The use of massage therapy has received increased attention in the treatment of chronic pain. However, barriers can hinder its use in nursing care. This study uses a qualitative methodology to explore professionals’ experiences regarding touch massage (TM) and identify barriers and facilitators for the implementation of this intervention.

Materials and methods
This study is part of a larger research program aimed at investigating the impact of TM on the experiences of patients with chronic pain hospitalized in two units of an internal medicine rehabilitation ward. Health care professionals (HCPs) were trained either to provide TM or to use of a massage-machine device according to their units. At the end of the trial, two focus groups were conducted with HCPs from each unit who took part in the training and agreed to discuss their experience: 10 caregivers from the TM group and 6 from the machine group. The focus group discussions were tape-recorded, transcribed and analyzed using thematic content analysis.

Results
Five themes emerged from thematic content analysis: perceived impact on patients, HCPs’ affective and cognitive experiences, patient-professionals relationships, organizational tensions, and conceptual tensions. Overall, the HCPs reported better general outcomes with TM than with the machine. They described positive effects on patients, HCPs, and their relationships. Regarding interventions’ implementation, the HCPs reported organizational barriers such as patients’ case complexity, work overload, and lack of time. Conceptual barriers such as ambivalence around the legitimacy of TM in nursing care were reported. TM was often described as a pleasure care that was considered a complementary approach and was overlooked despite its perceived benefits.

Conclusion
Despite the perceived benefits of TM reported by the HCPs, ambivalence arose around the legitimacy of this intervention. This result emphasizes the importance of changing HCPs’ attitudes regarding a given intervention to facilitate its implementation.
The impact of adjuvant chemotherapy on survival in mucinous and non-mucinous rectal adenocarcinoma patients after TME surgery
Authors: Vernmark Karolina , Knutsen Annika , Loftås Per , Sun Xiao-Feng 
Published: February 2023

IntroductionThe value of adjuvant chemotherapy for rectal cancer patients is debated and varies in different subgroups. One such subgroup is mucinous adenocarcinoma (MAC), which is more treatment resistant compared to non-mucinous adenocarcinoma (NMAC). To date, mucinous histology is not taken into account when deciding on adjuvant treatment strategy. This is the first study to exclusively include patients with rectal cancer, then separate MAC and NMAC and compare the survival in patients that had or did not have adjuvant chemotherapy.Material and methodsThe study included retrospective register data from 365 Swedish patients with stage II-IV rectal adenocarcinoma, 56 patients with MAC and 309 patients with NMAC. All patients were considered curative, had surgery with total mesorectal excision in 2004–2013, and were followed up until death or 2021.ResultsPatients with MAC that had adjuvant chemotherapy had better overall survival (OS, HR 0.42; CI 95%: 0.19–0.93;p= 0.032) and a trend towards better cancer-specific survival (CSS, HR 0.41 CI 95%: 0.17–1.03;p= 0.057) compared to patients without chemotherapy (HR 0.42; CI 95%: 0.19–0.93;p= 0.032). The difference in OS was still significant even after adjusting for sex, age, stage, differentiation, neoadjuvant chemotherapy and preoperative radiotherapy (HR 0.40; CI 95%: 0.17–0.92;p= 0.031). There was no such difference in the NMAC patients except in the stage-by-stage subgroup analyses where patients in stage IV had better survival after adjuvant chemotherapy.ConclusionsThere may be a difference in treatment response to adjuvant chemotherapy between MAC and NMAC patients. Patients with MAC could possibly benefit from adjuvant chemotherapy in stages II-IV. Further studies are however needed to confirm these results.
Sociometric network analysis in illicit drugs research: A scoping review
Authors: Zakimi Naomi , Greer Alissa , Bouchard Martin , Dhillon Arshpreet , Ritter Alison 
Published: February 2023

BackgroundSociometric or whole network analysis, a method used to analyze relational patterns among social actors, emphasizes the role of social structure in shaping behaviour. Such method has been applied to many aspects of illicit drug research, including in the areas of public health, epidemiology, and criminology. Previous reviews about social networks and drugs have lacked a focus on the use of sociometric network analysis for illicit drugs research across disciplines. The current scoping review aimed to provide an overview of the sociometric network analysis methods used in illicit drugs research and to assess how such methods could be used for future research.MethodsA systematic search of six databases (Web of Science, ProQuest Sociology Collection, Political Science Complete, PubMed, Criminal Justice Abstracts, and PsycINFO) returned 72 relevant studies that met the inclusion criteria. To be included, studies had to mention illicit drugs and use whole social network analysis as one of their methods. Studies were summarized quantitatively and qualitatively using a data-charting form and a description of the studies’ main topics.ResultsSociometric network analysis in illicit drugs research has grown in popularity in the last decade, using mostly descriptive network metrics, such as degree centrality (72.2%) and density (44.4%). Studies were found to belong to three study domains. The first, drug crimes investigated network resilience and collaboration patterns in drug trafficking networks. The second domain, public health, focused on the social networks and social support of people who use drugs. Finally, the third domain focused on the collaboration networks of policy, law enforcement, and service providers.ConclusionFuture illicit drugs research using whole network SNA should include more diverse data sources and samples, incorporate mixed and qualitative methods, and apply social network analysis to study drug policy.
Strategy and additive technologies as the catalyst for outsourcing, process innovation and operational effectiveness
Authors: Tegethoff Thomas , Santa Ricardo , Cayón Edgardo , Scavarda Annibal 
Published: February 2023

PurposeThere is rising interest in Industry 4.0 as a factor in the competitiveness of the organization. Although many companies are aware of the importance of Industry 4.0, the development of such initiatives in Colombia is slow. Consequently, this research investigates the impact of additive technologies as part of the Industry 4.0 concept on operational effectiveness and, therefore, the competitiveness of the organization and tries to establish the factors that hinder the adequate implementation of such new, innovative technologies.Design/Methodology/ApproachStructural equation modeling was used to analyze the antecedents and outcomes of operational effectiveness. To this end, 946 usable questionnaires were collected from managers and personnel from Colombian organizations.FindingsInitial findings show that management is aware of Industry 4.0 concepts and implements strategies for such initiatives. Nevertheless, neither process innovation nor additive technologies have a significant impact on operational effectiveness and therefore on the competitiveness of the organization.Practical implicationsThe implementation of new innovative technologies requires the closure of the digital gap between urban and rural areas and between large and medium and small enterprises. Similarly, the concept of Industry 4.0 as a new, innovative manufacturing concept requires a transversal implementation to increase the competitiveness of the organization.Originality/ValueThe value of this paper lies in discussing the current technological and human capabilities and strategies that Colombian organizations, as an example of a developing nation, should improve to leverage the benefits of Industry 4.0 to remain competitive. The results are probably generalizable to other regions in developing countries throughout the world.
The metabolic profile of waist to hip ratio–A multi-cohort study
Authors: Lind Lars , Ahmad Shafqat , Elmståhl Sölve , Fall Tove 
Published: February 2023

Background
The genetic background of general obesity and fat distribution is different, pointing to separate underlying physiology. Here, we searched for metabolites and lipoprotein particles associated with fat distribution, measured as waist/hip ratio adjusted for fat mass (WHRadjfatmass), and general adiposity measured as percentage fat mass.

Method
The sex-stratified association of 791 metabolites detected by liquid chromatography–mass spectrometry (LC-MS) and 91 lipoprotein particles measured by nuclear magnetic spectroscopy (NMR) with WHRadjfatmass and fat mass were assessed using three population-based cohorts: EpiHealth (n = 2350) as discovery cohort, with PIVUS (n = 603) and POEM (n = 502) as replication cohorts.

Results
Of the 193 LC-MS-metabolites being associated with WHRadjfatmass in EpiHealth (false discovery rate (FDR) <5%), 52 were replicated in a meta-analysis of PIVUS and POEM. Nine metabolites, including ceramides, sphingomyelins or glycerophosphatidylcholines, were inversely associated with WHRadjfatmass in both sexes. Two of the sphingomyelins (d18:2/24:1, d18:1/24:2 and d18:2/24:2) were not associated with fat mass (p>0.50). Out of 91, 82 lipoprotein particles were associated with WHRadjfatmass in EpiHealth and 42 were replicated. Fourteen of those were associated in both sexes and belonged to very-large or large HDL particles, all being inversely associated with both WHRadjfatmass and fat mass.

Conclusion
Two sphingomyelins were inversely linked to body fat distribution in both men and women without being associated with fat mass, while very-large and large HDL particles were inversely associated with both fat distribution and fat mass. If these metabolites represent a link between an impaired fat distribution and cardiometabolic diseases remains to be established.
The use of virtual reality in screening for preclinical Alzheimer’s disease: A scoping review protocol
Authors: Tian Yuan , Kuruvilla Maneesh V. , Park Mira 
Published: February 2023

Introduction
Preclinical Alzheimer’s disease (AD) represents the earliest phase of AD, often years before the onset of mild cognitive impairment (MCI). There is a pressing focus on identifying individuals in the preclinical AD phase to alter the trajectory or impact of the disease potentially. Increasingly, Virtual Reality (VR) technology is being used to support a diagnosis of AD. While VR technology has been applied to the assessment of MCI and AD, studies about how best to utilize VR as a screening tool for preclinical AD are limited and discordant. The objectives of this review are to synthesize the evidence pertaining to the use of VR as a screening tool for preclinical AD as well as to identify factors that need to be considered when utilizing VR to screen for preclinical AD.

Methods and analysis
The methodological framework proposed by Arksey and O’Malley (2005) will be introduced to guide the conduction of the scoping review, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) (2018) will be used to organize and structure the review. PubMed, Web of Science, Scopus, ScienceDirect and Google Scholar will be used to search for literature. Obtained studies will be screened for eligibility based on predefined exclusion criteria. A narrative synthesis of eligible studies will be performed, after tabulating the extracted data from existing literature, to answer the research questions.

Ethics and dissemination
Ethical approval is not required for this scoping review. Findings will be disseminated through conference presentations, publication in a peer-reviewed journal, and discussions among professional networks in the research domain combining neuroscience and information and communications technology (ICT).

Registration details
This protocol has been registered on Open Science Framework (OSF). Relevant materials and potential following updates are available at https://osf.io/aqmyu.
Mobilfunk ja – aber Masten und Antennen bitte nicht hier! Diskursive Aushandlungsprozesse um die Standortwahl von Sendeanlagen in Deutschland
Authors: Dittel Julia , Weber Florian , Berr Karsten , Kühne Olaf 
Published: February 2023

A stable and nationwide mobile network coverage is increasingly regarded as essential. This requires an expansion of mobile networks throughout the country. However, the installation of masts and antennas has often been the subject of conflict in Germany, especially due to fears about potential health effects of electromagnetic fields. Transmitters become both a trigger and a target of social protests. From a discourse-theoretical perspective, we identify central lines of argumentation in the German cellular network conflicts. A triangulation of quantitatively oriented and qualitative analysis components forms the methodological basis. Regional case studies provide an opportunity to identify local differences. A comparison of past and recent conflicts reveals discursive shifts over time. Debates about the possible health effects of mobile radio were particularly contentious in the context of UMTS mobile phone expansion at the turn of the millennium. The (planned) installation of transmitters at the local level often sparked this discussion. During the expansion of the 5G network, in addition to the debate about the health risks of the technology, questions are now being raised about whether and to whom the expansion is necessary. Compared to the previous period of investigation, local conflicts about transmitters now appear to be less virulent and can be found primarily in southern and southwestern Germany.
Some new Gronwall–Bellman–Bihari type integral inequality associated
with ψ-Hilfer fractional derivative
Authors: Meftah Badreddine , Foukrach Djamal 
Published: February 2023

Abstract
Natural phenomena as well as problems encountered in pure
and applied sciences are modeled by ordinary, partial or integral
differential equations. Most of these problems have a nonlinear
aspect which makes their studies difficult, or even impossible.
For this, they must resort to other alternatives; among the methods used
is the integral inequalities approach, which allows the study of
quantitative and qualitative properties of solutions such as
existence, uniqueness, delimitation, oscillation, and stability.
In this study, we present some new integral inequalities of the
Gronwall–Bellman–Bihari type associated with the fractional derivative of ψ-Hilfer, which represents a strong tool and is applicable in the study of certain differential equations. Several known results
are derived and some applications to ordinary differential equations
are provided to demonstrate the effectiveness of our finding.
Monocyte distribution width alterations and cytokine storm are modulated by circulating histones
Authors: Ligi Daniela , Lo Sasso Bruna , Della Franca Chiara , Giglio Rosaria Vincenza , Agnello Luisa , Ciaccio Marcello , Mannello Ferdinando 
Published: February 2023

Abstract

Objectives
Extracellular histone levels are associated with the severity of many human pathologies, including sepsis and COVID-19. This study aimed to investigate the role of extracellular histones on monocyte distribution width (MDW), and their effect on the release of cytokines by blood cells.

Methods
Peripheral venous blood was collected from healthy subjects and treated with different doses of a histone mixture (range 0–200 μg/mL) to analyze MDW modifications up-to 3 h and digital microscopy of blood smears. Plasma obtained after 3 h of histone treatment were assayed to evaluate a panel of 24 inflammatory cytokines.

Results
MDW values significantly increased in a time- and dose-dependent manner. These findings are associated with the histone-induced modifications of cell volume, cytoplasmic granularity, vacuolization, and nuclear structure of monocytes, promoting their heterogeneity without affecting their count. After 3 h of treatment almost all cytokines significantly increased in a dose-dependent manner. The most relevant response was shown by the significantly increased G-CSF levels, and by the increase of IL-1β, IL-6, MIP-1β, and IL-8 at the histone doses of 50, 100, and 200 µg/mL. VEGF, IP-10, GM-CSF, TNF-α, Eotaxin, and IL-2 were also up-regulated, and a lower but significant increase was observed for IL-15, IL-5, IL-17, bFGF, IL-10, IFN-γ, MCP-1, and IL-9.

Conclusions
Circulating histones critically induce functional alterations of monocytes mirrored by MDW, monocyte anisocytosis, and hyperinflammation/cytokine storm in sepsis and COVID-19. MDW and circulating histones may be useful tools to predict higher risks of worst outcomes.
A Shimura–Shintani correspondence for rigid analytic cocycles of higher weight
Authors: Negrini Isabella 
Published: February 2023

Abstract
This paper takes the first steps towards a systematic study of additive rigid meromorphic cocycles of higher weight. These were introduced by Darmon and Vonk, who focused on additive cocycles of weight two and their multiplicative lifts. After classifying certain rigid meromorphic cocycles of weight

2
⁢
k

{2k}

, we construct an explicit holomorphic kernel function realizing
a Shimura–Shintani style correspondence from modular forms of
weight

k
+

1
/
2

{k+1/2}

and level

4
⁢

p
2

{4p^{2}}

to
rigid analytic cocycles of weight

2
⁢
k

{2k}

on

SL
2

⁡

(

ℤ
⁢

[

1
/
p

]

)

{\operatorname{SL}_{2}(\mathbb{Z}[1/p])}

.
Assessments of recent Global Geopotential Models based on GPS/levelling and gravity data along coastal zones of Egypt
Authors: Al Shouny Ahmed , Khalil Ragab , Kamel Abdullah , Miky Yehia 
Published: February 2023

Abstract
The orthometric height has an essential role in a variety of civil engineering projects and it is defined as the length of the curved plumbline from a point (on the earth surface) to its intersection with the geoid surface. Leveling process is considered as the most accurate technique for obtaining these heights. However, regardless of its potentials, it is tedious, costly, and time consuming. Recently many organizations and research centers have developed multi Global Geopotential Models (GGMs) depending on several types of available gravity and height datasets to estimate orthometric heights from GNSS measurements. In this study, we present an evaluation and assessment of the accuracy of five of recent and popular GGMS: XGM2016, XGM2019e, EIGEN-6C4, GO_CONS_GCF_2_TIM_R6e, and EGM2008 using actual 145 GNSS/leveling points and 96 terrestrial gravity points. The goal of this research is to find the best fit model along the study area located along the coastal zones of Egypt with distances of about 1,970 km for further determination of geoid modeling at regional scale. The selection of these areas basically was due to their developmental, urban, and economical importance and their continuous need for protection works to fight against the coastal erosion caused by climate change and global warming. The results indicated that for geoid undulation, GO_CONS_GCF_2_TIM_R6e model is the best fit GGM for the estimation of geoid model along Mediterranean Sea coastal line, while XGM2019e_2159 model is the best suitable for coastal line of the Red Sea. And regarding the gravity anomalies, the most reliable GGMs for this study area are XGM2019e_2159 and EIGEN-6C4 for Bouguer and free-air gravity anomaly, respectively.
Uncertainty assessment of 3D geological models based on spatial diffusion and merging model
Authors: Nie Xiaoyan , Lu Cai , Luo Kai 
Published: February 2023

AbstractThe geological model plays an important role in geophysics and engineering geology. The data source of geological modeling comes from interpretation data, borehole data, and outcrop data. Due to economic and technical limitations, it is impossible to obtain highly accurate and high-density data sources. The sparsity and inaccuracy of data sources lead to the uncertainty in geological models. Unlike the problem of probability, there is not enough samples for a geological model. Spatial diffusion model and merging model are introduced, which are more satisfied with the cognition of uncertainty than the existing methods. And then, using conditional information entropy, a quantification method of geological uncertainty, is proposed. Compared with the approaches of information entropy, this method took full account of the constraints of geological laws. Based on the uncertainty models and conditional information entropy, a framework of uncertainty assessment in geological models is established. It is not necessary in our framework to create multiple geological models, which is a time-consuming and laborious task. The application of Hashan survey located at north of China shows that the method and framework of this study are reasonable and effective.
Towards low polymer content transparent composites via novel integration engineering
Authors: Wu Jiamin , Liang Yunyi , Wu Yingji , Li Jianzhang , Lu Jianxiong , Lam Su Shiung , Naushad Mu. , Sonne Christian , Xia Changlei 
Published: February 2023

Abstract
The high polymer and low wood content of current transparent wood has limitation in the mechanical strength and hence obstruct green sustainable transition of the building industry. In this study, a novel method for manufacturing transparent wood was reported by minimizing the usage of polyethylene glycol using partial impregnation followed by a densification approach. The delignified wood was firstly partially impregnated by polyethylene glycol, and subsequently compressed to eliminate pores for the compressed transparent wood, providing the strong hydrogen bonds and dense structures for transparent wood. The wood content of the novel compressed transparent wood was dramatically increased to 64%, compared with the uncompressed transparent wood of 25%. Additionally, the obtained compressed transparent wood demonstrated satisfactory optical transmittance, suitable thermal energy storage, and superior mechanical strengths owing to the formation of densely packed microstructures. This novel, sustainable, and low-cost transparent wood was easy to be manufactured while having increased mechanical and energy-saving characteristics compared to those available in the existing market.