bluuebunny/crossref_metadata_2025_split huggingface dataset:
ELEIÇÃO ESCOLAR E ENSINO MÉDIO: EXPERIÊNCIAS DE ESCOLARIZAÇÃO NA ARGENTINA E NO BRASIL
Authors: Botelho Mariana Mataluna , Unzué Martín 
Published: April 2023

O trabalho apresenta os resultados da pesquisa de doutorado que analisou, de forma comparada, o ensino médio público brasileiro e argentino. Especificamente, se expõem as motivações da eleição escolar e os sentidos atribuídos à experiência escolar pelos estudantes de dois colégios vinculados a Universidades públicas: o Colégio de Aplicação da Universidade de São Paulo e o “Colégio Nacional de Buenos Aires”, da Universidade de Buenos Aires. Ambas as instituições são consideradas como como diferenciadas no âmbito do sistema de ensino público de ambos os países, no que se refere a trajetórias, recursos econômicos e também humanos. Palavras-chave:
APRENDIZAGEM CRIATIVA COMO UM DOS PILARES PARA A CAPACITAÇÃO DE PROFESSORES DO ENSINO BÁSICO: UNIVERSIDADES CRIATIVAS EM AÇÃO
Authors: De Oliveira Carolina Maciel , Brito Rebeca Simoes , Szkudlarek Ariani Cavazzani , Sampaio Lilian Messias , Alvim Rafael De Oliveira , Mourão Junior Carlos Alberto , De Oliveira Camila Maciel 
Published: April 2023

Introdução: O processo lúdico e criativo, possibilitam o desenvolvimento de algumas das competências sócio emocionais preconizadas pela Base Nacional Comum Curricular. Objetivo: Realizar a capacitação de um conjunto de professores da rede pública do município de Curitiba, utilizando a metodologia “Little Hearts Changing Lives” (LHCL) como ferramenta facilitadora para a abordagem temática sobre reeducação alimentar. Método: Os dados qualitativos descritos foram observados durante a Oficina de Capacitação para professores do município de Curitiba, Paraná, Brasil, subdividida em 4 encontros no período de 8 semanas. Resultados: Os 23 professores capacitados foram co-criadores das ações destinadas aos 380 escolares do ensino básico, através do processo de remixagem do manual proposto pelo programa LHCL. Conclusão: O conceito de aprendizagem criativa aplicado à capacitação de professores fora contemplado em suas quatro dimensões: construção entusiasmada (“passion”) de projetos reais (“projects”), através de atividades lúdicas (“play”), em colaboração (“peers”), consolidando o processo de aquisição de conhecimento.
PRÁTICAS INOVADORAS NA FORMAÇÃO EM DOCÊNCIA INCLUSIVA
Authors: Bezerra Cláudia Barreto , Oliveira Ana Flávia Teodoro 
Published: April 2023

ResumoO presente artigo tem como objetivo relatar a prática de inclusão escolar e formação docente no Centro de Ensino e Pesquisa Aplicada à Educação da Universidade Federal de Goiás. Apresenta considerações atuais sobre a formação de professores para a educação especial nos cursos de licenciatura e o direito dos alunos com especificidades, ao desenvolvimento acadêmico e social compatível com a meta da plena participação de todos. O trabalho desenvolvido é uma proposta coletiva de construção de um projeto de ensino envolvendo professores, alunos e os licenciandos da universidade como mediadores pedagógicos. Em uma dinâmica de trabalho colaborativo, os professores experientes e os futuros educadores acompanham o desempenho escolar de alunos com diferentes necessidades pedagógicas, ampliando metodologias que considerem os diferentes desenvolvimentos escolares. Obteve-se o destaque na valorização das potencialidades dos alunos e não das deficiências, concluindo que o diálogo entre os cursos de licenciatura e o ensino básico, com a inserção dos licenciandos em sala de aula e com formação docente específica, promove a inclusão e amplia a capacitação docente.
Impact of the diaphyseal femoral deformity on the lower limb alignment in osteoarthritic varus knees
Authors: Batailler Cécile , Naaim Alexandre , Daxhelet Jeremy , Lustig Sébastien , Ollivier Matthieu , Parratte Sebastien 
Published: April 2023

AimsThe impact of a diaphyseal femoral deformity on knee alignment varies according to its severity and localization. The aims of this study were to determine a method of assessing the impact of diaphyseal femoral deformities on knee alignment for the varus knee, and to evaluate the reliability and the reproducibility of this method in a large cohort of osteoarthritic patients.MethodsAll patients who underwent a knee arthroplasty from 2019 to 2021 were included. Exclusion criteria were genu valgus, flexion contracture (> 5°), previous femoral osteotomy or fracture, total hip arthroplasty, and femoral rotational disorder. A total of 205 patients met the inclusion criteria. The mean age was 62.2 years (SD 8.4). The mean BMI was 33.1 kg/m2 (SD 5.5). The radiological measurements were performed twice by two independent reviewers, and included hip knee ankle (HKA) angle, mechanical medial distal femoral angle (mMDFA), anatomical medial distal femoral angle (aMDFA), femoral neck shaft angle (NSA), femoral bowing angle (FBow), the distance between the knee centre and the top of the FBow (DK), and the angle representing the FBow impact on the knee (C’KS angle).ResultsThe FBow impact on the mMDFA can be measured by the C’KS angle. The C’KS angle took the localization (length DK) and the importance (FBow angle) of the FBow into consideration. The mean FBow angle was 4.4° (SD 2.4; 0 to 12.5). The mean C’KS angle was 1.8° (SD 1.1; 0 to 5.8). Overall, 84 knees (41%) had a severe FBow (> 5°). The radiological measurements showed very good to excellent intraobserver and interobserver agreements. The C’KS increased significantly when the length DK decreased and the FBow angle increased (p < 0.001).ConclusionThe impact of the diaphyseal femoral deformity on the mechanical femoral axis is measured by the C’KS angle, a reliable and reproducible measurement.Cite this article: Bone Jt Open 2023;4(4):262–272.
Macroeconomic impact of Ebola outbreaks in Sub-Saharan Africa and potential mitigation of GDP loss with prophylactic Ebola vaccination programs
Authors: Morrison Laura T. R. , Anderson Benjamin , Brower Alice , Talbird Sandra E. , Buell Naomi , MacDonald Pia D. M. , Metz Laurent , Gaudig Maren , Oriol Mathieu Valérie , Honeycutt Amanda A. 
Published: April 2023

Introduction
Decisions about prevention of and response to Ebola outbreaks require an understanding of the macroeconomic implications of these interventions. Prophylactic vaccines hold promise to mitigate the negative economic impacts of infectious disease outbreaks. The objective of this study was to evaluate the relationship between outbreak size and economic impact among countries with recorded Ebola outbreaks and to quantify the hypothetical benefits of prophylactic Ebola vaccination interventions in these outbreaks.

Methods
The synthetic control method was used to estimate the causal impacts of Ebola outbreaks on per capita gross domestic product (GDP) of five countries in sub-Saharan Africa that have previously experienced Ebola outbreaks between 2000 and 2016, where no vaccines were deployed. Using illustrative assumptions about vaccine coverage, efficacy, and protective immunity, the potential economic benefits of prophylactic Ebola vaccination were estimated using the number of cases in an outbreak as a key indicator.

Results
The impact of Ebola outbreaks on the macroeconomy of the selected countries led to a decline in GDP of up to 36%, which was greatest in the third year after the onset of each outbreak and increased exponentially with the size of outbreak (i.e., number of reported cases). Over three years, the aggregate loss estimated for Sierra Leone from its 2014–2016 outbreak is estimated at 16.1 billion International$. Prophylactic vaccination could have prevented up to 89% of an outbreak’s negative impact on GDP, reducing the outbreak’s impact to as little as 1.6% of GDP lost.

Conclusion
This study supports the case that macroeconomic returns are associated with prophylactic Ebola vaccination. Our findings support recommendations for prophylactic Ebola vaccination as a core component of prevention and response measures for global health security.
Age Differences in Core Symptoms and Symptom Relationships in Patients With Irritable Bowel Syndrome: A Network Analysis
Authors: Yang Pei-Lin , Kamp Kendra J. , Burr Robert L. , Tang Hsin-Yi (Jean) , Dobra Adrian , Shulman Robert J. , Heitkemper Margaret M. 
Published: April 2023

INTRODUCTION:
Irritable bowel syndrome (IBS) is a common disorder of gut-brain interaction, characterized by symptoms of abdominal pain and changes in bowel habits. It often co-occurs with extraintestinal somatic and psychological symptoms. However, the nature of the interrelationships among these symptoms is unclear. Although previous studies have noted age differences in IBS prevalence and specific symptom severity, it remains unknown whether specific symptoms and symptom relationships may differ by age.

METHODS:
Symptom data were collected in 355 adults with IBS (mean age 41.4 years, 86.2% female). Network analysis was used to examine the interrelationships among 28 symptoms and to identify the core symptoms driving the symptom structure between young (≤45 years) vs older (>45 years) adults with IBS. We evaluated 3 network properties between the 2 age groups: network structure, edge (connection) strength, and global strength.

RESULTS:
In both age groups, fatigue was the top core symptom. Anxiety was a second core symptom in the younger age group, but not the older age group. Intestinal gas and/or bloating symptoms also exerted considerable influences in both age groups. The overall symptom structure and connectivity were found to be similar regardless of age.

DISCUSSION:
Network analysis suggests fatigue is a critical target for symptom management in adults with IBS, regardless of age. Comorbid anxiety is likely an important treatment focus for young adults with IBS. Rome V criteria update could consider the importance of intestinal gas and bloating symptoms. Additional replication with larger diverse IBS cohorts is warranted to verify our results.
Impact of Cold Snare vs Cold Forceps Resection of Diminutive Adenomas on Segmental Incomplete Resection Rate
Authors: Van Jeremy , Alsayid Muhammad , Ma Karen , Vemulapalli Krishna , Rex Douglas , Melson Joshua 
Published: April 2023

INTRODUCTION:
Polypectomy technique, for diminutive lesion resection, is variable among colonoscopists using either cold snare polypectomy (CSP) or cold forceps polypectomy (CFP). While it is well described that CSP is a preferred technique to resect small lesions, there is little data evaluating the impact resection techniques have on metachronous adenoma burden. The aim of this study was to evaluate the rate of incomplete resection attributable to CSP and CFP of diminutive adenomas.

METHODS:
This is a 2-center retrospective cohort study evaluating the segmental incomplete resection rate (S-IRR) of diminutive tubular adenomas (TA). S-IRR was calculated by subtracting the segmental metachronous adenoma rate in a specific colonic segment without adenoma from segments with adenoma on index colonoscopy. The primary outcome was the S-IRR of diminutive TA resected by CSP or CFP on index colonoscopy.

RESULTS:
A total of 1,504 patients were included in the analysis: 1,235 with TA <6 mm and 269 with TA 6–9 mm as the most advanced lesion. The S-IRR in a segment that had a <6-mm TA incompletely resected by CFP on index colonoscopy was 13%. The S-IRR in a segment that had a <6-mm TA incompletely resected by CSP was 0%. Among 12 included colonoscopists, the range of overall S-IRR was 1.1%–24.4% with an average S-IRR of 10.3%.

DISCUSSION:
S-IRR was 13% higher with CFP resection of diminutive TA than with CSP. A proposed S-IRR metric of <5% is a target goal for all diminutive polyp resection because 3/12 colonoscopists achieved this low rate. S-IRR can be used as a methodology to compare and quantify the difference in segmental metachronous adenoma burden across various polypectomy removal methods.
Top-Four Primaries Help Moderate Candidates via Crossover Voting: The Case of the 2022 Alaska Election Reforms
Authors: Anderson Sarah E. , Butler Daniel M. , Harbridge-Yong Laurel , Marshall Renae 
Published: April 2023

Abstract
Concerns about polarization and the difficulty moderate candidates have in winning primary elections have driven several electoral reform efforts in recent decades. In this article, we leverage reforms prior to the 2022 elections in Alaska to assess whether the top-four primary is likely to help moderate candidates succeed. We evaluate three mechanisms by which the top-four might help moderates: by allowing them to advance from the primary and compete for votes from the more moderate general electorate, by changing the composition of the primary electorate and/or by facilitating crossover voting during the primary. Our analysis suggests that the top-four primary creates opportunities for cross-party voting that can enhance the electoral prospects of moderate candidates.
Numerical solution for a nonlinear diffusion model with source terms
Authors: Jangveladze Temur , Kiguradze Zurab , Kratsashvili Maia , Neta Beny 
Published: April 2023

Abstract
The nonlinear diffusion system with source terms is studied.
This model is derived via Maxwell equations describing electromagnetic field propagation in media.
The uniqueness of the solution and its behavior as

t
→
∞

t\to\infty

are proved.
We also prove that the finite difference approximation converges in space and time.
Numerical implementation with various experiments for different values of the input parameters is performed to validate the theoretical conclusions.
Microbial xylanase aided biobleaching effect on multiple components of lignocelluloses biomass based pulp and paper: a review
Authors: Dukare Ajinath , Sharma Kanika , Kautkar Sheshrao , Dhakane-Lad Jyoti , Yadav Rahul , Nadanathangam Vigneshwaran , Saxena Sujata 
Published: April 2023

Abstract
Due to discharge of hazardous organochlorine compounds and absorbable organic halogen compounds in the effluent, the pulp and paper industries are trying to alter the bleaching process to limit the use of chlorine compounds and comply with regulatory, environmental, and market demands. With progress in biotechnology, enzyme technologies can effectively pre-treat lignocellulosic biomass in the pulp and paper making process. Usually, these enzymatic processes reduce the environmental impact of traditional pulp and paper-making processes, lower the overall production cost, and enhance product quality. Microbial xylanases are the potential bio-bleaching candidate due to their renewable, mild operating, highly specific, and eco-friendly nature. Xylanase enhances the efficacy of the bleaching process by breaking the β-1, 4-glycosidic backbone of the re-precipitated xylan network and removing the trapped lignin from the pulp fibers. Xylanolytic action positively influences the kappa number, hexenuronic acid, chromophore compounds release, pulp crystallinity, morphology and many other attributes of pulp. The present review comprehensively highlights the microbial xylanolytic system, its mechanism, and its application in pulp bioleaching. With the recent development, the paper delineates the xylanase-aided bleaching effects on pulp, paper, and effluent attributes aimed to reduce bleaching chemical use, AOX formation, and energy use in the pulp refining process.
TIPE2 knockdown exacerbates isoflurane-induced postoperative cognitive impairment in mice by inducing activation of STAT3 and NF-κB signaling pathways
Authors: Jian Rui , He Xin 
Published: April 2023

Abstract

Objective
Anesthetic exposure causes learning and memory impairment, the mechanisms of which remain unknown. It has been reported that tumor necrosis factor-α-inducer protein 8-like 2 (TIPE2) is a newly discovered immune negative regulator that is essential for maintaining immune homeostasis. This study aimed to examine the role of TIPE2 in isoflurane-induced postoperative cognitive decline (POCD).

Methods
An AAV empty vector and AAV shTIPE2 vector for the knockdown of TIPE2 were injected into the dorsal hippocampus of mice. Mice were continuously exposed to 1.5% isoflurane followed by abdominal exploration. Behavioral tests including the open field test and fear conditioning test were performed on the third and fourth day post-operation. Apoptosis was detected by terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling staining. The kits were used to detect the activity of antioxidant enzymes. Inflammatory cytokine levels were detected by enzyme-linked immunosorbent assay. Signal transducer and activator of transcription 3 (STAT3) and nuclear factor-κB (NF-κB) signaling pathway activities were detected by western blotting.

Results
TIPE2 expression increased after isoflurane anesthesia and surgery. TIPE2 deficiency aggravated cognitive impairment in mice and further caused apoptosis and oxidative stress in hippocampal neurons. TIPE2 deficiency induced microglial activation and increased secretion of proinflammatory cytokines. In addition, TIPE2 deficiency promoted STAT3 and NF-κB signaling activation induced by isoflurane anesthesia and after surgery.

Conclusion
TIPE2 may play a neuroprotective role in POCD by regulating STAT3 and NF-κB pathways.
Legal Protection for Account Owners on Marketplace as an Effort to Prevent Loss Due to Data Leaks
Authors: Lamdayoung Cindy Thia 
Published: April 2023

In the digital age, there are a lot of people or society who choose e-commerce rather than the conventional transaction. E-commerce usually done in online marketplace applications such as Tokopedia, Bukalapak, Traveloka, and so on. Based on the data, Indonesia ranks as one of the highest e-commerce growth rate in the world. This is a good sign, because it means that marketplace companies in Indonesia can also compete and have a great opportunity to be more global. However, as a result of these developments, of course there are also negative impacts that come together. One of the negative impacts is the issue of security/security of the linked accounts in the marketplace application. A lot of data-leak phenomena occur frequently and this is an urgent matter to be prevented and resolved. Marketplace’s account owners must have a legal things that protect them and prevent any various kinds of losses that can arise due to data leakage. And the marketplace platform providers also have to make some policies to protect their app users from the data leakage.
Cancel Culture in the Frame of Comparison of Indonesia and South Korea
Authors: Anjarini Dipta Ninggar 
Published: April 2023

Cancel culture is a culture that is carried out by the community in the form of canceling or retaking its support for an object of publik consumption or influencer after it is deemed to have violated the norms applicable in society. This study comparing comprehensively the cancel culture in Indonesia and South Korea. The research was carried out using the literature study method by exploring theoretical references that were relevant to the research subject or problems that would be discussed further. The result of this study reveals that the intensity and the implementation of cancel culture has a significant impact to the effectiveness of social control. ‘cancel culture’ is often used as an excuse to reject other people's opinions that are different from the opinions of the netizen. Therefore, further research is needed on the implementation of cancel culture in Indonesia, accompanied by good quality digital literation competencies, so that cancel culture is not only used as an excuse to convey hate comments but also provides a deterrent impact and social sanctions for public figures who are being ‘cancelled’ by the community.
Human Rights Juridic Review on Transgenders as a Tool of Social Control in Indonesia
Authors: Sihombing Saling Sabrina 
Published: April 2023

This study discusses how to apply human rights law as a means of social control over gender in Indonesia, how to treat and improve the community for transgender people in Indonesia, the inhibiting factors for implementing protection for transgender people in Indonesia and how to respect the rights of transgender groups. The method used in this scientific article is a normative-empirical legal research method. The normative-empirical legal research method is basically a combination of a normative legal approach or based on statutory regulations with the addition of various empirical elements or seeing every legal event within the scope of the general public. It can be concluded that the normative-empirical legal research method is an approach or implementation of normative law in every aspect of legal events that occur in the community. The aim is to find out the importance of providing protection to transgender people as Indonesian citizens and further about legal protection for transgender people and how it is implemented. From the results of the study, it can be seen that legal protection as an Indonesian citizen from discrimination has indeed been running but has not been maximized. The problem with providing protection to transgender people is that there is still no firm stance from the government in dealing with the issue of protection for transgender people and the absence of legal regulations specifically made for transgender conditions and the attitude of people who are still indifferent to transgender people.
The First Malaysian Multidisciplinary Team Heart Failure Clinic: A Tertiary Cardiac Centre Experience
Authors: Shariff Raja Ezman Raja , Koh Hui Beng , Sabian Intan Safarinaz , Quah Wy Jin , Ong Siew Hoon , Sulong Maizatu Akma , Jaafar Jamalia , Devi Subramaniam Thulasi , Chan Jenny Ai Wei , Rahim Aizai Azan Abdul , Teoh Chee Kiang , Ghazi Azmee Mohd 
Published: April 2023

Aims: There remains a large emphasis on optimisation of guideline-directed medical therapy (GDMT) during the ‘vulnerable phase’ of acute heart failure (HF). Multidisciplinary team heart failure (MDT-HF) clinics have been shown to be beneficial in increasing key GDMT prescriptions. The aim of this study was to report on the authors’ experience running the first Malaysian early, post-discharge MDT-HF clinic. Methods: A retrospective review of the MDT-HF clinic was conducted in Institut Jantung Negara, Malaysia, over a 3-year period (2019–22). Results: A total of 186 patients and 488 clinic encounters were identified. Patients were mainly of New York Heart Association functional class II (45.2%) and had a mean left ventricular ejection fraction of 26.1%. Blood investigations on average were stable, aside from estimated glomerular filtration rate (≤60 ml/min/1.73 m2 in 53.2% of patients) and NT-pro-brain natriuretic peptide (mean of 5,201 pg/ml). Common comorbidities included diabetes (60.0%), hypertension (60.0%), dyslipidaemia (46.2%) and chronic kidney disease (38.2%). A high proportion of new prescriptions and uptitration of medication were for key GDMTs, while the majority of downtitrations were for diuretics. A substantial number of patients were on three or four GDMTs (37.6% and 49.5%, respectively). Counselling provided during the MDT-HF clinic was also analysed, which included education on self-care and medication management, and lifestyle counselling. Conclusion: MDT-based services offer evidence-based, holistic care to HF patients. Hopefully, this description of the establishment of the first MDT-HF clinic should encourage the development of similar services across the region.