bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFEKTIVITAS PENANGANAN KASUS KEKERASAN TERHADAP PEREMPUAN DAN ANAK OLEH DINAS PEMBERDAYAAN PEREMPUAN DAN PERLINDUNGAN ANAK KOTA SORONG
Authors: Rahmi Aulia , Kitaby A. Magfirah Ummul 
Published: July 2023

Violence is an act or threat to oneself, a group of people or society or individuals that causes death, loss, psychology, trauma or deprivation of rights. Cases of violence against women and children are nothing new. There is a lot of violence against women and children that often happens around us. Cases of violence against women and children are increasing every year. The change of Sorong City to become the Capital City of Southwest Papua Province had a major influence on cases of violence against women and children in Sorong City, with an increase in population, the number of cases of violence also increased.
Cases of violence against women and children come in various forms of violence. Ranging from physical and psychological violence, domestic violence, neglect, harassment to trafficking in persons. Cases of violence against women and children may occur in the social environment, including the family environment, the workplace, to educational institutions.
A study on virulence determinants and antimicrobial resistance among Enterococci isolates
Authors: Rajan Reena , Dhandapani Karthikeyan 
Published: July 2023

Introduction and Aim: Presence of virulence factors may cause increased persistence of Enterococci in the healthcare environment, increase ability to colonise inpatients and thereby result in the transmission of infection. The present study was performed to detect the presence of virulence traits among the clinical strains of Enterococci and to determine its association between virulence factors and susceptibility to various antibiotics.

Materials and Methods: Clinical isolates of Enterococci were identified to species level by conventional method and Vitek 2 automated method and subjected to antibiotic susceptibility testing using disk diffusion and Minimum Inhibitory Concentration (MIC) method. Presence of hemolysin, gelatinase and biofilm was detected by phenotypic method.

Results: Out of 708 isolates from urine 39 (5.51%) Enterococcus faecalis, and 3 isolates each of Enterococcus faecium (0.42 %) and Enterococcus durans (0.42 %) were biofilm producers. Beta hemolysin production was detected in 342 (48.30%) E. faecalis obtained from urine and 9/48 (18.75 %) from pus. Out of the isolates studied, 9/774 (1.16 %) isolates were found to be positive for beta-hemolysin production, gelatinase and biofilm production. All the 9 (100.00 %) isolates were resistant to penicillin, high level gentamicin, ciprofloxacin and levofloxacin.

Conclusion: Virulence factors described in Enterococci enable these organisms to colonise patient tissue, increase resistance to antimicrobial agents and aggravate infection outcome.
Promising catheters to reduce hospital-acquired urinary tract infections
Authors: Renukaprasad Abhijnya K. , Suman Ethel , Jeppu Udayalaxmi , Paul S. Harsha 
Published: July 2023

Introduction and Aim: Hospital-acquired infection with multidrug-resistant bacteria following urinary catheter use in hospitalized patients is mainly due to the biofilm-forming ability of these bacteria. It becomes essential to look at the other options of treatment of such urinary tract infections (UTI) and one such option has been the use of bacteriophages. The study aimed to compare the biofilms formed by uropathogenic Escherichia coli on three different types of urinary catheters in the presence of crude coliphage and sub-inhibitory concentration of ciprofloxacin.

Materials and Methods: It was an Institution based experimental study. A total of 10 red rubber (latex) catheter pieces, 10 Foley (PVC) catheter pieces and 10 silicone Foley catheter pieces were used for the study. Crude coliphage suspension was prepared from sewage samples taken from the sewage treatment plant. Biofilm production by ten uropathogenic E. coli isolates on these catheters was determined by Kolter and O’Toole’s method with certain modifications. Biofilm assay was repeated with conditions using crude bacteriophage and sub-inhibitory concentration. An electron micrograph of the catheter pieces was taken to visualize the biofilm formed. P value of 0.05 was considered statistically significant.

Results: It was observed that, in the presence of crude bacteriophage there was a significant reduction in the biofilm formation on all three catheters (p 0.05). Also, there was a significant reduction in biofilm production in the presence of sub-inhibitory concentration of ciprofloxacin on silicone Foley’s catheter (p=0.001) but not on red rubber catheter or PVC Foley’s catheter (p 0.05). It was also observed that in some of the isolates the colony counts increased following the addition of ciprofloxacin in case of PVC Foley catheters.

Conclusion: Bacteriophage-coated catheters may be the gateway to overcoming the hurdle of multidrug-resistant catheter-associated urinary tract infection.
Lipoprotein lipase gene polymorphisms and their association with the development and severity of carotid artery stenosis
Authors: Shaker Khazaal Mahmood , Bader Hamdan Farqad , Sharhan Al-Mayah Qasim 
Published: July 2023

Introduction and Aim: In developed countries, carotid artery stenosis (CAS) has a considerable impact on mortality and disability rates. Genetic risk factors for CAS have also been linked, in addition to environmental risk factors. This study sought to determine whether there may be a link between three polymorphisms in the LPL gene and the emergence of CAS.

Materials and Methods: One hundred and twenty participants were enrolled in this case-control study, including 60 individuals with CAS and 60 healthy subjects serving as the control group. The demographic and clinical data were collected from each participant. Whole blood samples were obtained to study the genomic DNA where a specific LPL gene fragment corresponding to the three single nucleotide polymorphisms (SNPs) rs320, rs328, and rs285 was amplified using designated primers. Restriction fragment length polymorphism analysis was used for genotyping.

Results: The mutant allele (C) of the rs285 polymorphism was more frequent in patients than controls (45% vs. 32.5%; OR=1.7, 95% CI= 1.01- 2.87; p=0.048). The TCC haplotype block (T allele of rs320, C allele of rs285, and C allele of rs328) was significantly more prevalent in patients compared to controls (OR= 2.0, 95% CI= 1.03-3.77, p= 0.039). On the other hand, controls (23.33%) had significantly more of the haplotype block GTG than did patients (8.33%) (OR = 0.3, 95% CI = 0.14-0.065, p = 0.002). The SNPs rs320 (D' = 0.63) and rs328 (D' = 0.61) have weak relationships with rs385.

Conclusion: The C allele of rs285 polymorphism could be considered a risk factor for CAS. While the haplotype block GTG was thought to play a protective role, the haplotype block TCC (T allele of rs320, C allele of rs285, and C allele of rs328) may increase the risk of CAS.
Isolation and characterization of bacteriophage targeting Enterococcus faecalis isolated from root canal infection (in vitro study)
Authors: F. Almelan Maha , Khalid Abbas Uroba , M. Al-Zubidi 
Published: July 2023

Introduction and Aim: Enterococcus faecalis, a Gram-positive bacterium inhabits the human and animal intestinal tracts and the environment. E. faecalis in addition to being implicated in a wide variety of infections in humans is considered the most common threat associated with recurrent root canal treatment failures. In this investigation we aimed to characterize E. faecalis strains isolated from chronic endodontic infection and evaluate the effect of a bacteriophage for its capability to eliminate E. faecalis biofilm formation.

Materials and Methods: This study involved 65 chronic endodontic infection samples which were studied for the prevalence of Enterococcus faecalis. The identification of E. faecalis was accomplished by a combination of biochemical testing and the sequencing of the 16S rRNA gene. Phages isolated from cow dung samples were purified and evaluated based on their capability of preventing the development of biofilms by Enterococcus faecalis on biotic surfaces.

Results: Of the 65 chronic endodontic infection samples studied nineteen tested positive for the presence of E. faecalis. E. faecalis strain K3 was found to be vancomycin resistant. Biofilm development on abiotic surfaces by E. faecalis strain K3 was shown to be greatly reduced after exposure to the enterococcal phage BAG1.

Conclusion: This investigation shows that the E. faecalis bacteriophage BAG1 significantly decreases the growth of E. faecalis biofilm on abiotic surfaces.
Correlation of serum gamma-glutamyl transferase and serum glutathione-S-transferase with PAP smear as screening tests for cervical cancer
Authors: Sowkanthika P. , D. S. Maitreyee , D’ Almeida Joylene , A. R. Shivashankara , S. S. Avinash , Premakumari E. , M. Malathi 
Published: July 2023

Introduction and Aim: Papanicolaou (PAP) smear has been the test of choice in screening for cervical cancer. However, biochemical parameters such as enzymes have been analyzed for their use in screening, diagnosis and prognosis of cervical cancer and cervical pre-malignancy. In our study we aimed to analyse serum gamma-glutamyl transferase (GGT) and Glutathione–S- transferase (GST) in screening for cervical cancer and correlate these activities with PAP smear results.

Materials and Methods: Women who tested positive (cases) or negative (controls) for PAP smear were the subjects of this study, and activities of GGT and GST were assayed in serum samples.

Results: Serum GST was significantly lower among the cases when compared to controls (p=0.005) while serum GGT did not differ significantly between the two groups. There was no significant correlation between GGT and GST activities both in cases and controls.

Conclusion: Serum GST showed statistically significant difference between newly diagnosed cases of cervical intraepithelial neoplasia and women testing negative for cervical intraepithelial neoplasia during screening. Further evaluation of serum enzymes as biomarkers for screening, diagnosis, and prognosis, with larger sample size and comparison between healthy controls, cervical premalignant lesions and cervical cancer are required. This would go a long way in establishing enzymes as sensitive biomarkers of cervical cancer.
Effectiveness of Mirena® LNG-IUS in treating women with endometrial hyperplasia and climacteric syndrome
Authors: Teppeeva Tanzilya , Karymshakova Kanysh , Makenzhanova Meerim , Zhumabekova Altynai 
Published: July 2023

Introduction and Aim: Endometrial hyperplasia (EH) is a common cause of malignant tumors and a major health risk for perimenopausal women. In this study, systemic immunological markers in women with climacteric syndrome (CS) and EH will be examined in relation to the EH treatment option Mirena® levonorgestrel-releasing intrauterine device (LNG-IUS).

Materials and Methods: Examining 350 premenopausal women, 84 (23.4%) were diagnosed with EH. The type of EH was identified in 84 patients using a histological study and a diagnostic curettage of the uterine cavity. In view of more severe and considerable systemic immunity abnormalities in women with CS and EH, the indirect effect of levonorgestrel's intrauterine microdose excretion on systemic immunity was examined.

Results: Mirena® LNG-IUS has an indirect immune-corrective effect on systemic and humoral immunity in women with EH who have a pathological climatic course. It does this by stabilizing the neutrophil pool, activating the receptor function, and stabilizing the absorption and metabolic activity of neutrophilic phagocytes in the humoral system.

Conclusion: Due to the pathological progression of menopause and the appearance of EH, alterations in women's reproductive system during this period led to a significant decrease in the signs of CS after the first month of using Mirena® LNG-IUS.
Da'wa Narration of Matchmaking in Opor Ayam Short Film
Authors: Azzahro Fatimah , Salama Hartini 
Published: July 2023

Background: The narration of women as wives in every age and culture is always conveyed using various methods. This diversity is increasingly being explored through the development of media and digital technology. Short films through the Youtube channel can also be a medium of dawah to narrate a matchmaking.
Purpose: The focus of this study is limited to how the topic of matchmaking is narrated in the short film “Opor Ayam” published by NU Online.
Design and methods: This study’s method is descriptive qualitative with verbal and visual narrative research data on the short film Opor Ayam published by NU Online in 2021. This research uses semiotics-signification theory to obtain a narrative structure for the meaning of matchmaking.
Results: The results show that the Opor Ayam film has four stages, namely equilibrium, disruption, disequilibrium and new-equilibrium as a narrative structure. The results of the discussion also show that the topic of matchmaking is conveyed as; (1) acceptable in religion, (2) must be based on religious provisions, (3) the narrative emphasizes that marriage through matchmaking is a familiarization and must be based on religion.
Integration of Technology in Education and its Impact on Learning and Teaching
Authors: Mdhlalose Dickson , Mlambo Gloria 
Published: July 2023

This study seeks to understand the effects of technology on education: teaching and learning. All the data used in this study comes from secondary sources. Information was gathered from several sources, including peer-reviewed journal papers, published and unpublished dissertations, online and print textbooks, and encyclopaedias. Findings: Evidence on the effects of technology is contradictory, according to a review of the relevant literature. Thanks to information technology developments, classroom collaboration between teachers and students is more efficient than ever. It broadens their academic and intellectual horizons, making students more versatile in the classroom. Due to the internet's accessibility, remote learning may now be supported by technological means. Students can use search engines to conduct research. Hardware failures, software incompatibilities between home and school, or non-existent internet connections, and outdated program versions are just some of the dependability problems that students and teachers face in the classroom. Because of developments in technology like graphical calculators, high-tech gadgets, and small cameras, dishonest students may now easily gain an edge over their classmates. Distractions in modern life may be traced back in large part to technological advancements. Students' health might be negatively impacted by excessive technology usage.
Fazedores de Cultura, Comedores de Patrimônio
Authors: Pieroni Gabriella Cristina 
Published: July 2023

A expressão “fazedores de cultura” surgiu no Brasil na última década no campo da participação social nas políticas culturais, e aponta para uma mudança conceitual que dá protagonismo aos agentes da sociedade na produção cultural do país. Transportando esta mudança de paradigmas para as políticas de preservação do patrimônio cultural, quem seriam os “comedores de patrimônio”? Observou-se nos últimos anos uma forte demanda pelo reconhecimento de práticas agroalimentares como patrimônio cultural. A partir da historicidade da Política de Salvaguarda do Patrimônio Imaterial executada pelo IPHAN, este artigo propõe uma reflexão sobre a relação entre Estado e sociedade civil na aplicação do instrumento legal do registro do Patrimônio Imaterial, especificamente para práticas culturais diretamente ligadas à alimentação, sejam elas agrícolas e/ou culinárias.
Comparison of methods for correcting QT interval in athletes and young people: A systematic review
Authors: Mahendran Shehane , Gupta Ishita , Davis Jason , Davis Angus J. , Orchard John W. , Orchard Jessica J. 
Published: July 2023

AbstractScreening elite athletes for conditions associated with sudden cardiac death is recommended by numerous international guidelines. Current athlete electrocardiogram interpretation criteria recommend the Bazett formula (QTcB) for correcting QT interval. However, other formulae may perform better at lower and higher heart rates (HR). This review aimed to examine the literature on various QT correction methods in athletes and young people aged 14−35 years and determine the most accurate method of calculating QTc in this population. A systematic review of MEDLINE, EMBASE, Scopus, and SportDiscus was performed. Papers comparing at least two different methods of QT interval correction in athletes or young people were included. Quality and risk of bias were assessed using a standardized tool. The search strategy identified 545 papers, of which 10 met the criteria and were included. Nine of these studies concluded that QTcB was least reliable for removing the effect of HR and was inaccurate at both high (>90 beats per min [BPM]) and low (<60 BPM) HRs. No studies supported the use of QTcB in athletes and young people. Alternative QT correction algorithms such as Fridericia (QTcF) produce more accurate correction of QT interval at HRs seen in athletes and young people. QTcB is less accurate at lower and higher HRs. QTcF has been shown to be more accurate in these HR ranges and may be preferred to QTcB for QTc calculation in athletes and young people. However, accurate QTc reference values for discrete HRs using alternative algorithms are not well established and require further research.
Negative frequency dependent selection unites ecology and evolution
Authors: Christie Mark R. , McNickle Gordon G. 
Published: July 2023

AbstractFrom genes to communities, understanding how diversity is maintained remains a fundamental question in biology. One challenging to identify, yet potentially ubiquitous, mechanism for the maintenance of diversity is negative frequency dependent selection (NFDS), which occurs when entities (e.g., genotypes, life history strategies, species) experience a per capita reduction in fitness with increases in relative abundance. Because NFDS allows rare entities to increase in frequency while preventing abundant entities from excluding others, we posit that negative frequency dependent selection plays a central role in the maintenance of diversity. In this review, we relate NFDS to coexistence, identify mechanisms of NFDS (e.g., mutualism, predation, parasitism), review strategies for identifying NFDS, and distinguish NFDS from other mechanisms of coexistence (e.g., storage effects, fluctuating selection). We also emphasize that NFDS is a key place where ecology and evolution intersect. Specifically, there are many examples of frequency dependent processes in ecology, but fewer cases that link this process to selection. Similarly, there are many examples of selection in evolution, but fewer cases that link changes in trait values to negative frequency dependence. Bridging these two well‐developed fields of ecology and evolution will allow for mechanistic insights into the maintenance of diversity at multiple levels.
Exploring the impact of hippocampal sclerosis on white matter tracts and memory in individuals with mesial temporal lobe epilepsy
Authors: Zanao Tamires A. , Seitz‐Holland Johanna , O'Donnell Lauren J. , Zhang Fan , Rathi Yogesh , Lopes Tátila M. , Pimentel‐Silva Luciana Ramalho , Yassuda Clarissa L. , Makris Nikos , Shenton Martha E. , Bouix Sylvain , Lyall Amanda E. , Cendes Fernando 
Published: July 2023

AbstractObjectiveTo investigate how the presence/side of hippocampal sclerosis (HS) are related to the white matter structure of cingulum bundle (CB), arcuate fasciculus (AF), and inferior longitudinal fasciculus (ILF) in mesial temporal lobe epilepsy (MTLE).MethodsWe acquired diffusion‐weighted magnetic resonance imaging (MRI) from 86 healthy and 71 individuals with MTLE (22 righ‐HS; right‐HS, 34 left‐HS; left‐HS, and 15 nonlesional MTLE). We utilized two‐tensor tractography and fiber clustering to compare fractional anisotropy (FA) of each side/tract between groups. Additionally, we examined the association between FA and nonverbal (WMS‐R) and verbal (WMS‐R, RAVLT codification) memory performance for MTLE individuals.ResultsWhite matter abnormalities depended on the side and presence of HS. The left‐HS demonstrated widespread abnormalities for all tracts, the right‐HS showed lower FA for ipsilateral tracts and the nonlesional MTLE group did not differ from healthy individuals. Results indicate no differences in verbal/nonverbal memory performance between the groups, but trend‐level associations between higher FA of visual memory and the left CB (r = 0.286, P = 0.018), verbal memory (RAVLT) and ‐left CB (r = 0.335, P = 0.005), ‐right CB (r = 0.286, P = 0.016), and ‐left AF (r = 0.287, P = 0.017).SignificanceOur results highlight that the presence and side of HS are crucial to understand the pathophysiology of MTLE. Specifically, left‐sided HS seems to be related to widespread bilateral white matter abnormalities. Future longitudinal studies should focus on developing diagnostic and treatment strategies dependent on HS's presence/side.
2D MXenes Embedded Perovskite Hydrogels for Efficient and Stable Solar Evaporation
Authors: Arshad Naila , Irshad Muhammad Sultan , Asghar M. Sohail , Alomar Muneerah , Tao Junyang , Shah M. A. K. Yousaf , Wang Xianbao , Guo Jinming , Wageh S. , Al‐Hartomy Omar A. , Kalam Abul , Hao Yabin , Ouyang Zhengbiao , Zhang Han 
Published: July 2023

AbstractSolar evaporation is a facile and promising technology to efficiently utilize renewable energy for freshwater production and seawater desalination. Here, the fabrication of self‐regenerating hydrogel composed of 2D‐MXenes nanosheets embedded in perovskite La 0.6Sr 0.4Co 0.2Fe 0.8O3−δ (LSCF)/polyvinyl alcohol hydrogels for efficient solar‐driven evaporation and seawater desalination is reported. The mixed dimensional LSCF/Ti3C2 composite features a localized surface plasmonic resonance effect in the polymeric network of polyvinyl alcohol endows excellent evaporation rates (1.98 kg m−2 h−1) under 1 k Wm−2 or one sun solar irradiation ascribed by hydrophilicity and broadband solar absorption (96%). Furthermore, the long‐term performance reveals smooth mass change (13.33 kg m−2) during 8 h under one sun. The composite hydrogel prompts the dilution of concentrated brines and redissolves it back to water (1.2 g NaCl/270 min) without impeding the evaporation rate without any salt‐accumulation. The present research offers a substantial opportunity for solar‐driven evaporation without any salt accumulation in real‐life applications.
Reproductive late effects after hematopoietic stem cell transplant in pediatric, adolescent, and young adult cancer survivors
Authors: Appiah Leslie C. , Moravek Molly , Hoefgen Holly , Rotz Seth , Childress Krista , Samis Jill , Benoit Janie , Rodriguez‐Wallberg Kenny , Anazodo Antoinette 
Published: July 2023

AbstractReproductive late effects after hematopoietic stem cell transplant can have a significant impact on cancer survivors’ quality of life. Potential late effects include gonadal insufficiency, genital graft‐versus‐host disease, uterine injury, psychosexual dysfunction, and an increased risk of breast and cervical cancer in patients treated with total body irradiation. Despite guidelines, screening and treatment are not standardized among at‐risk patients. Provider barriers include lack of knowledge of at‐risk therapies and evidenced‐based guidelines. Patient barriers include a reluctance to report symptoms and lack of awareness of treatment options. System barriers include inefficient implementation of screening tools and poor dissemination of guidelines to providers who serve as the medical home for survivors. This review guides the clinician in identifying and managing reproductive late effects after hematopoietic stem cell transplant to improve outcomes.