bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of modifying negative interpretation bias toward ambiguous social stimuli across eating and personality disorders
Authors: An Zhen , Kwag Kyung Hwa , Kim Mirihae , Yang Jae‐Won , Shin Hui‐Ji , Treasure Janet , Kim Youl‐Ri 
Published: March 2023

AbstractObjectiveHeightened sensitivity toward social rejection has been implicated in eating disorders (ED) and personality disorder (PD). This study examined the effect of a cognitive bias modification training (CBM‐I) targeting the interpretation of ambiguous social situations in individuals with comorbid ED and PD.MethodA total of 128 participants [33 with ED and PD, 22 with ED‐only, 22 with PD‐only, and 51 healthy controls (HC)] were recruited from a hospital and university settings, and included in the final analyses. The participants were randomly assigned to a CBM‐I task with benign resolutions or a control task with neutral resolutions in a counterbalanced order in two sessions using a within‐subject design. Interpretation bias toward social stimuli was measured using the ambiguous sentence completion task before and after completing the assigned task.ResultsThe CBM‐I task increased benign and decreased negative interpretations with large effect sizes in the diagnostic groups, and with a moderate effect size in the HC group. Participants' anxiety levels were also reduced after the task. The size of the change in negative interpretation was positively associated with baseline negative affect, and negatively associated with baseline positive affect.DiscussionThe results suggest that modifying interpretation bias has the potential as a transdiagnostic target of treatment for ED and PD, and a fully powered clinical trial with consecutive sessions would be warranted.Public SignificanceParticipants with eating disorders and/or personality disorder, and healthy controls completed a single session of a cognitive training intervention targeting rejection sensitivity. The training produced a large decrease in negative interpretation in the diagnostic groups, and a moderate effect in healthy controls. The findings indicate that training for positive processing of social information may be of value to augment treatment in conditions such as eating disorders and personality disorder, in which there are high levels of rejection sensitivity.
Harnessing Deep Neural Networks to Analyze Multi‐Channel Anion Sensing Characteristics of a Ru(II)‐Pyrazolyl‐Bis(Benzimidazole) Complex
Authors: Deb Sourav , Sahoo Anik , Baitalik Sujoy 
Published: March 2023

AbstractIn this work, the anion‐responsive conduct of a Ru(II)‐bipyridine complex incorporating pyrazolyl‐bis (benzimidazole) ligand is thoroughly investigated in acetonitrile and water via absorption and emission spectroscopy as well as by square‐wave voltammetry (SWV). Substantial alteration of the photo‐redox behavior of the complex is observed in the presence of the selected anions. The free form of the complex exhibits emission indicating the “on‐state”, while inclusion of anions leads to quenching of emission and represents the “off‐state”. The restoration of the initial state of the complex is feasible in the presence of acid and the process is reversible and can be recycled. In essence, the complex functions as anion‐ and acid‐responsive molecular switches. Additionally, we applied herein neural network based deep learning methodologies, viz. Artificial Neural Networks (ANNs) and Adaptive Neuro‐Fuzzy Inference System (ANFIS)} for thorough analysis and fully understand the multi‐channel anion sensing behavior of the complex.
An online service function chain orchestration method for profit maximization in edge computing networks
Authors: Yang Chen , Hu Bingtao , Feng Yixiong , Huang Hua , Lai Haoshan , Tan Jianrong 
Published: March 2023

AbstractNetwork function virtualization (NFV) is an appealing solution that transforms complex network functions from dedicated hardware to software instances running in a virtualized environment. However, some new challenges will arise when deploying virtual network functions to meet the needs of NFV and edge‐computing (EC) enabled 5G networks. In this paper, we focus on the service function chain (SFC) orchestration problem for EC‐enabled networks to maximize the profit of network service providers. First, the mathematical model of SFC orchestration in NFV and EC‐enabled networks is defined. Then, a two‐stage heuristic algorithm is proposed to optimize the total revenue. Finally, the performance of the method is evaluated by simulation experiments and the results show its effectiveness.
Autopsy of a failed trial part 1: A qualitative investigation of clinician's views on and experiences of the implementation of the DAISIES trial in UK‐based intensive eating disorder services
Authors: Phillips Matthew , İnce Başak , Webb Hannah , Dalton Bethan , McCombie Catherine , Irish Madeleine , Mercado Daniela , Peachey Gemma , Zenasni Zohra , Himmerich Hubertus , Robinson Paul , Arcelus Jon , Byford Sarah , Treasure Janet , Landau Sabine , Lawrence Vanessa , Schmidt Ulrike 
Published: March 2023

AbstractObjectiveThe DAISIES trial, comparing inpatient and stepped‐care day patient treatment for adults with severe anorexia nervosa was prematurely terminated in March 2022 due to poor recruitment. This qualitative study seeks to understand the difficulties faced during the trial by investigating stakeholders' views on and experiences of its implementation.MethodSemi‐structured interview and focus group transcripts, and trial management and oversight group meeting minutes from May 2020‐June 2022 were analysed using thematic analysis. Participants were 47 clinicians and co‐investigators involved with the DAISIES trial. The Non‐Adoption, Abandonment, Scale‐up, Spread, and Sustainability (NASSS) framework was applied to the interpretive themes to classify barriers and facilitators to implementation.ResultsFive themes were identified: incompatible participation interests; changing standard practice; concerns around clinical management; systemic capacity and capability issues; and Covid‐19 disrupting implementation. Applying the NASSS framework indicated the greatest implementation challenges to arise with the adopters (e.g. patients, clinicians), the organisational systems (e.g. service capacity), and the wider socio‐political context (e.g. Covid‐19 closing services).ConclusionsOur findings emphasise the top‐down impact of systemic‐level research implementation challenges. The impact of the Covid‐19 pandemic accentuated pre‐existing organisational barriers to trial implementation within intensive eating disorder services, further limiting the capacity for research.
A robust‐link controller placement model for large‐scale software defined networks
Authors: Wang Zhenqi , Li Yi , Guan Shaopeng 
Published: March 2023

AbstractThe software defined network (SDN) is a novel flexible network architecture. For the purpose of facilitating management, multiple controllers need to be placed in large‐scale SDN. When a link failure occurs, the path can be re‐planned by the control layer. However, unreasonable controller placement scheme brings about a sharp latency increase between controllers and switches. The reliability of the SDN is therefore affected. To this end, we define a link robust distance (LRD) by considering the states during link failures and non‐link failures. Then, we use it design a robust link controller placement model (RLCPM) which can reduce the impact of link failures on the delay between the controller and the switch. In addition, we design a heuristic algorithm with low‐time complexity to solve the RLCPM more effectively. Experimental results show that, compared with other models, RLCPM simplifies the controller placement problem when considering a link failure. The maximum latency between controllers and switches of the obtained controller placement scheme is lower.
Metal‐Organic Cycle/Cage (MOC)‐Based Supramolecular Photosensitizers: A Promising Strategy to Construct Robust Phototherapeutic Agents
Authors: Tuo Wei , Li Yuanyuan , Olenyuk Bogdan , Sun Yao , Sun Yan , Stang Peter J. 
Published: March 2023

AbstractMetal‐organic cycles/cages (MOCs) are discrete and well‐defined molecular entities formed by coordination between metal centers and organic donors. To date, two‐dimensional and three‐dimensional suprastructures such as triangle, rhomboid, hexagon, and cube have been prepared. The tunable sizes and shapes endow MOCs with unique properties and promising applications in catalysis, sensors, and biomaterials. This review mainly covers achievements in the application of MOCs photosensitizers for the elimination of tumors and bacteria. Finally, it also discusses the future of MOCs for the design of novel type of photosensitizers and the possibility for novel therapeutic modalities.
Alpha‐ketoglutaric acid based polymeric particles for cutaneous wound healing
Authors: Jaggarapu Madhan M. C. S. , Ghosh Deepanjan , Johnston Tyler , Yaron Jordan R. , Mangal Joslyn L. , Inamdar Sahil , Gosangi Mallikarjun , Rege Kaushal , Acharya Abhinav P. 
Published: March 2023

AbstractMetabolites are not only involved in energy pathways but can also act as signaling molecules. Herein, we demonstrate that polyesters of alpha‐ketoglutararte (paKG) can be generated by reacting aKG with aliphatic diols of different lengths, which release aKG in a sustained manner. paKG polymer‐based microparticles generated via emulsion‐evaporation technique lead to faster keratinocyte wound closures in a scratch assay test. Moreover, paKG microparticles also led to faster wound healing responses in an excisional wound model in live mice. Overall, this study shows that paKG MPs that release aKG in a sustained manner can be used to develop regenerative therapeutic responses.
MentorOn: A peer mentoring program developed for COVID‐19 times
Authors: Patel Kira N. , Lincoln Brenna , Gomez Lester A. Mejia , Lopez Ana C. , Ting Tobin , Lund Terese J. , Liang Belle 
Published: March 2023

AbstractBurgeoning research has documented COVID–19's detrimental impacts globally, especially on the lives of adolescents. The present study examined the positive influences of a virtual, cross‐age peer mentoring program on the development of adolescent participants in the face of the hardships created by the pandemic. In particular, this study focuses on the experiences of high school participants who served as both mentors and mentees in the program. Semi‐structured interviews with participating high schoolers (n = 13) were coded and analyzed using the thematic analysis process. The interview data indicated that increased social support, the agency in prosocial pursuits, and greater purpose engagement resulted from their participation in the program. Results are discussed in the context of self‐determination theory: youths' needs for relatedness, competence, and autonomy. The program met these basic needs among participants which in turn supported purpose exploration during the pandemic.
Causal associations and shared genetics between hypertension and COVID‐19
Authors: Baranova Ancha , Cao Hongbao , Zhang Fuquan 
Published: March 2023

AbstractTo evaluate the genetic relationship between hypertension and COVID‐19 and explore the molecular pathways linking hypertension to COVID‐19. We performed genetic correlation and Mendelian randomization (MR) analyses to assess potential associations between hypertension and hospitalized COVID‐19. We compared genome‐wide association signals to reveal shared genetic variation between hypertension and hospitalized COVID‐19. Moreover, hypertension‐driven molecular pathways were constructed based on large‐scale literature data to understand the influence of hypertension on COVID‐19 at the molecular level. Hypertension has a positive genetic correlation with COVID‐19 (rg = 0.19). The MR analyses indicate that genetic liability to hypertension confers a causal effect on hospitalized COVID‐19 (odds ratio [OR]: 1.05, confidence interval [CI]: 1.00–1.09, p = 0.030). Hypertension and hospitalized COVID‐19 have three overlapping loci and share eight protein‐coding risk genes, including ABO, CSF2, FUT2, IZUMO1, MAMSTR, NPNT, RASIP1, and WNT3. Molecular pathway analysis suggests that hypertension may promote the development of COVID‐19 through the induction of inflammatory pathways. Our study suggests that genetically determined hypertension may increase the risk for severe COVID‐19. The shared genetic variation and the connecting molecular pathways may underline causal links between hypertension and COVID‐19.
Lung adenocarcinoma presenting with eosinophilic erythroderma associated with anti‐KRT6B antibodies: Case report
Authors: Erden Nihan , Khoshbakht Saba , Yaycioglu Arda , Kizilirmak Ali , Kayalar Özgecan , Demirkesen Cüyan , Kulaç Ibrahim , Özkan Küçük Nazlı Ezgi , Ozlu Nurhan , Ruzicka Thomas , Wollenberg Andreas , Vural Seçil 
Published: March 2023

AbstractParaneoplastic erythroderma (PE) is a rare and potentially life‐threatening inflammatory condition associated with malignancy. PE may potentially develop due to antibodies produced against tumoral antigens that cross‐react with epidermal structures. We report a patient with paraneoplastic eosinophilic erythroderma associated with lung adenocarcinoma. Erythroderma and eosinophilia subsided after wedge‐resection of the tumour. To tackle the pathogenesis of PE in this patient, we performed western blot analysis (WB) using healthy human skin tissue lysate and the patient's serum. Samples were analysed first by immunoprecipitation of autoantibody‐target protein complexes and mass spectrometry to reveal the corresponding protein. After incubating patient serum with skin proteins, in WB, we could observe a distinct band around 60 kD. Later, immunoprecipitation for mass spectrometry showed a bar in the same area which was not present in healthy controls. Mass spectrometric analysis revealed that KRT6B might be the potential target protein. In this patient with PE, which resolved after surgical removal of lung adenocarcinoma, the antibody production to tumoral antigens cross‐reacting with keratins in skin may have initiated the dermatitis.
The utility and safety of diode laser in endoscopic stapes surgery
Authors: Plodpai Yuvatiya 
Published: March 2023

AbstractObjectiveThe advantages of laser stapedotomy are less trauma and more precise and minimally invasive techniques; however, the potential risk of overheating from the laser combined with the endoscope tip must be considered. This study aimed to assess the efficacy and safety of diode lasers for endoscopic stapes surgery.MethodsA retrospective review of 56 patients with otosclerosis who underwent primary endoscopic stapedotomy with a diode laser from 2017 to 2020 was conducted. Demographic data, intraoperative findings, preoperative and postoperative audiological assessments, and postoperative complications were analyzed.ResultsThere was no statistically significant difference between the preoperative and postoperative bone conduction thresholds. The mean postoperative air‐bone gap (ABG) improved significantly compared to the preoperative ABG (4.07 vs. 35.43 dB, p < .001). The postoperative ABG closure within 10 dB at 6 and 12 months was achieved in 87.50% and 91.07% of patients, respectively. The postoperative pain scores at 4 and 24 h were 2.55 and 0.39, respectively. Immediate postoperative vertigo was reported in 12.50% of patients, with 100% complete recovery 2 months after surgery. The chorda tympani nerve was preserved in all the cases. Postoperative taste disturbances at 2 and 12 months were observed in 17.86% and 1.79% of patients, respectively.ConclusionThe diode laser in endoscopic stapedotomy is a safe and effective technique that provides satisfactory hearing outcomes. Temporary taste disturbances during the early postoperative period are a concern. The handheld diode laser delivery system is suitable for an endoscopic approach and is an alternative armamentarium for the treatment of otosclerosis.Level of evidence: IV.
Microjoule‐Level Mid‐Infrared Femtosecond Pulse Generation in Hollow‐Core Fibers
Authors: Deng Ang , Gavara Trivikramarao , Hassan Muhammad Rosdi Abu , Xiong Daiqi , Hasan Md Imran , Chang Wonkeun 
Published: March 2023

AbstractA fiber‐based approach that generates mid‐infrared femtosecond pulses in the 3–4 m spectral region with microjoule‐level single pulse energy is demonstrated. This is realized in a piece of gas‐filled antiresonant hollow‐core fiber that is pumped by a two‐micron light source. A rapid variation of the dispersion near a structural resonance of the fiber creates a phase‐matching point in mid‐infrared, which mediates the frequency‐down conversion. Femtosecond pulses centered at 3.16 m wavelength with the pulse energy of more than 1 J are generated, achieving a conversion efficiency as high as 8.2%. The emission wavelength is determined solely by the dielectric wall thickness of cladding elements, while the yield is subject to other experimental parameters. This, combined with high power‐handling capability of hollow‐core fibers, makes it possible to power scale the mid‐infrared output by either increasing the pulse energy or repetition rate of the pump. The technique presents a new pathway to build an all‐fiber‐based mid‐infrared supercontinuum source, which promises to be a powerful new tool for ultrahigh sensitivity molecular spectroscopy.
A single session of high‐energy microwave axillary hyperhidrosis and osmidrosis therapy: Key pretherapeutic assessment and outcome analysis
Authors: Wang Yu‐Hsin , Cheng Chun‐Yu , Chang Shyue‐Luen , Hu Sindy , Huang Yau‐Li 
Published: March 2023

AbstractBackgroundMicrowave therapy is used to treat axillary hyperhidrosis and osmidrosis. Even while a “danger zone” has been identified and reports of potential complications from nerve injury have been made, there has been little real‐world discussion regarding whether there is any pretreatment evaluation key factor that may lower the risk. Furthermore, the efficacy of a single treatment and the safety of high‐energy therapies have not been well investigated.ObjectiveThe aim of this study is to demonstrate the key aspects of pre‐therapeutic assessment, efficacy, and suitability of a single treatment, as well as the safety of high‐energy treatments.MethodsFifteen patients with axillary hyperhidrosis (AH) and axillary osmidrosis (AO) between ages of 20 and 50 had pretherapeutic ultrasonography and clinical assessments performed followed by a single‐pass microwave treatment using the miraDry system at energy level 5. The severity of AH and AO was evaluated using the Hyperhidrosis Disease Severity Scale and Odor‐10 scale, respectively, at baseline, 1 month, 3 months, and 1 year after treatment. Adverse reactions were recorded at each point of evaluation.ResultsOut of 30 treatment areas, 14 have a danger zone. Female gender, a small mid‐upper arm circumference, and a low body mass index (BMI) are all associated risk factors. The average Hyperhidrosis Disease Severity Scale score decreased from 3.1 ± 0.7 to 1.3 ± 0.5 (p < 0.001), while the odor‐10 score declined from 7.1 ± 1.6 to 3.0 ± 1.6 (p < 0.001), indicating a significant improvement in AH and AO. Most of the unfavorable treatment effects disappeared within the first month.LimitationsThis study has no objective quantitative measurement of axillary odor severity and sweat assessment.ConclusionFemale patients, those with a smaller mid–upper arm circumference, and those with a low BMI should be treated with extra caution, and the tumescent anesthetic dose may be increased based on safety. A high‐energy microwave treatment procedure performed in a single session is a safe and effective therapeutic option with good recovery.
Effect of alloying elements on aqueous corrosion of nickel‐based alloys at high temperatures: A review
Authors: Karimihaghighi Razieh , Naghizadeh Masoumeh 
Published: March 2023

AbstractNickel‐based alloys are well‐known multicomponent alloys with a composition carefully balanced to provide the desired properties for various industrial applications. While these alloys are corrosion resistant, under severe conditions corrosion can still occur, which can result in serious damage to a system in operation. To improve their reliability, the composition of nickel‐based alloys can be tailored to particular operating conditions. To improve their corrosion resistance, alloying elements such as chromium, molybdenum (+tungsten), and copper can be added, which promote the oxide formation process and thereby contribute to oxide passivity. This paper reviews and draws conclusions from existing literature on nickel‐based alloy corrosion and oxide formation in high‐temperature environments.
Stress corrosion of copper in sulfide solutions: Variations in pH‐buffer, strain rate, and temperature
Authors: Taxén Claes , Moya Núñez Alice , Lilja Christina 
Published: March 2023

AbstractCopper is the intended canister material for the disposal of spent nuclear fuel in Sweden. At repository depth the groundwater may contain dissolved sulfide. The main goal for this work is to study the tendency for stress corrosion of copper in sulfide solutions and examine the influence of various experimental parameters on stress corrosion. Slow strain rate testing was performed on copper test rods in solutions with 1.0 mM sulfide. The pH was kept near neutral with phosphate or borate buffer. The test matrix included variations in temperature, strain rate, and duration of the tests as well as salt and buffer concentrations. Cross‐sections of the specimens after testing were investigated using scanning electron microscope/energy dispersive X‐ray spectroscopy detector. Stress–strain curves do not reveal any signs of stress corrosion. However, intergranular corrosion in the shape of crack and pit‐like features developed in all tests with 1.0 mM sulfide. The length of the deepest features in all these tests was of the same order of magnitude (10–20 µm). The suggested mechanism proposes that crack‐like features originate at the surface of the copper metal from the oxidation of grain boundaries that behave as slightly less noble.
Progress of Hydrophobic Ionogels: A Review
Authors: Wan Xiaodong , He Yunfeng , Xu Ziyi , Li Caicong , Yang Canhui 
Published: March 2023

AbstractThe emergence of hydrophobic ionogels composed of hydrophobic polymer matrices and hydrophobic ionic liquids has drastically broadened the applications of ionic devices, especially for underwater explorations. Compared with traditional ionogels, hydrophobic ones are capable of achieving long‐term stability in ambient and aqueous environments. In this review, the latest research developments of intrinsically hydrophobic ionogels are summarized, with particular emphases placed on the materials, mechanisms and applications. The basic issues about hydrophobic ionogels, including the material systems, dynamic gelation bonds and network structures are elucidated. The up‐to‐date advent of the ambient/underwater applications of hydrophobic ionogels concerning adhesion, self‐healing, and sensing are comprehensively summarized. Special attention is paid to underwater scenarios considering the rapid development of marine explorations and the intrinsic properties of hydrophobic ionogels. Finally, the current challenges and immediate opportunities of this emerging yet fast‐developing research field are discussed.