bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growth performance and antioxidant status of giant gourami given different levels of astaxanthin supplementation
Authors: Sofian , , Jusadi Dedi , Nuryati Sri 
Published: September 2023

ABSTRACT As stocking density is known as a stress factor in fish. This study aimed to evaluate the effect of dietary astaxanthin supplementation on growth performance and antioxidant status in giant gourami under normal (100 fish/m3) and high (400 fish/m3) stocking density. Addition of astaxanthin in the feed was done by coating method. The experimental fish used were giant gourami with average body weight of 3.0±0.12 g. Fish were reared for 60 days in 100×50×50 cm3-sized-aquariums containing 150 L of water. Feed was given at satiation method twice a day at 09.00 and 17.00 pm. Results showed that fish reared in high stocking density and fed on the diet supplemented with astaxanthin 100 mg/kg diet produced the best growth performance. Addition of astaxanthin did not affect the antioxidant activity of giant gourami. Keywords: giant gourami, astaxanthin, growth performance, antioxidant status ABSTRAK Padat tebar tinggi merupakan salah satu faktor yang dapat menyebabkan stres pada ikan budidaya. Tujuan penelitian ini adalah untuk mengevaluasi pengaruh penambahan astaxanthin melalui pakan terhadap kinerja pertumbuhan dan status antioksidan ikan gurami pada pemeliharaan kepadatan normal (100 ekor/m3) dan kepadatan tinggi (400 ekor/m3). Penambahan astaxanthin pada pakan dilakukan dengan metode pelapisan (coating). Ikan uji yang digunakan adalah benih ikan gurami berukuran bobot rata-rata 3,0±0,12 g. Ikan dipelihara selama 60 hari dalam akuarium berukuran 100×50×50 cm3 berisi air 150 L. Pakan diberikan secara at satiation dengan frekuensi pemberian pakan sebanyak dua kali sehari pada pukul 09.00 dan 17.00 WIB. Hasil penelitian menunjukkan bahwa ikan yang dipelihara pada kepadatan tinggi dan diberi pakan dengan penambahan astaxanthin sebesar 100 mg/kg pakan menghasilkan kinerja pertumbuhan yang optimal. Penambahan astaxanthin sebesar 100 dan 200 mg/kg pakan tidak mempengaruhi status antioksidan pada ikan gurami. Kata kunci: ikan gurami, astaxanthin, pertumbuhan, status antioksidan
Spermatogenesis of male catfish Clarias sp. fed diet supplemeted with purwoceng extract
Authors: Bertha Poppy Dea , Junior Muhammad Zairin , Soelistyowati Dinar Tri 
Published: September 2023

ABSTRACT Purwoceng Pimpinella alpina Molk has been a commercial medicinal plant that their root could be used as aphrodisiac, diuretic, and body fit enhancer. This research was performed to evaluated the effect of purwoceng on spermatogenesis of the male catfish Clarias sp. consisted of testis weight, gonado somatic index (GSI), and spermatocrite levels. The treatment comprised administering purwoceng extract through the feed at a dose of 0; 2.5; 5; 7.5 g/kg of feed. Experimental fish used were male catfish Clarias sp. with initial body weight of 200–300 g at the density of 10 fish/tank. Male catfish were maintained in tank sized 2×1,5×1 m3, filled with water at 60–70 cm deep. The result showed that purwoceng extract at a dose of 5 g/kg mixed in the feed increased testis weight, GSI values, and spermatocrite levels in adult male catfish. Keywords: purwoceng extract, spermatogenesis, catfish ABSTRAK Purwoceng Pimpinella alpina Molk merupakan tanaman herbal komersial yang akarnya dilaporkan berkhasiat sebagai obat afrodisiak, diuretik, dan tonik. Penelitian ini bertujuan untuk mengevaluasi pengaruh ekstrak purwoceng terhadap perkembangan testis ikan lele Clarias sp. yang meliputi peningkatan bobot testis, nilai GSI, serta nilai spermatokrit. Perlakuan terdiri atas pemberian ekstrak purwoceng melalui pakan dengan dosis 0; 2,5; 5 dan 7,5 g/kg pakan. Adapun ikan yang diujicobakan pada penelitian adalah ikan lele jantan dengan bobot awal 200–300 g dan padat tebar 10 ekor/bak. Pemeliharaan ikan dilakukan pada bak berukuran 2×1,5×1 m3 yang diisi air dengan ketinggian 60–70 cm. Hasil percobaan menunjukkan bahwa pemberian ekstrak purwoceng dengan dosis 5 g/kg yang dicampur dalam pakan meningkatkan nilai bobot testis, nilai GSI dan kadar spermatokrit pada lele jantan dewasa. Kata kunci: ekstrak purwoceng, spermatogenesis, ikan lele
STRATEGI MENDAMPINGI DAN MENSTIMULASI DALAM MENINGKATKAN MEMBACA ANAK USIA DINI MELALUI CERGAM (CERITA BERGAMBAR)
Authors: Amalia Dina , Rosdiana Aliva 
Published: September 2023

Requirements for entry into primary school are not only based on the age limit of the child, but also on reading requirements. Besides that, the lack of interesting image visualization media makes it seem monotonous and boring for children. The purpose of this dedication to the community is to provide knowledge for teachers and parents at Ilman Nafi' tutoring in Kudus Regency regarding strategies to assist and stimulate early childhood reading. Calistung stands for reading, writing and calculating, these three are basic abilities that a person must possess in order to learn other things more easily. The method of counseling activities starts from event preparation, pre-test before giving material, giving material through power point slides, post-test evaluation, and closing. The instrument in providing material is power point, to carry out the pre-test and post-test using a questionnaire. The output to be achieved is that the teacher and parents make the Cergam (Cerita Bergambar) media and practice and apply it so that they can increase children's interest in reading. The PkM gap analysis is to minimize the need for Calistung through fun reading strategies with Cergam media. The results of the service obtained a pre-test score of 15% and an increase in the post-test score to 100%, the increase in scores from before and after giving the material shows that the counseling has succeeded in increasing knowledge for teachers and parents of Ilman Nafi's tutoring.

Abstrak
Persyaratan untuk masuk ke sekolah dasar tidak hanya didasarkan pada batas usia anak, tetapi juga pada persyaratan membaca. Selain itu kurangnya media visualisasi gambar yang menarik sehingga terkesan monoton dan membosankan bagi anak. Tujuan Pengabdian kepada Masyarakat ini untuk memberikan pengetahuan bagi guru dan orang tua di bimbingan belajar Ilman Nafi’ Kabupaten Kudus mengenai strategi mendampingi dan menstimulasi membaca anak usia dini. Calistung adalah singkatan dari membaca, menulis, dan menghitung, ketiganya merupakan kemampuan dasar yang harus dimiliki seseorang agar dapat mempelajari hal lain dengan lebih mudah. Metode kegiatan penyuluhan mulai dari persiapan acara, pre-test sebelum pemberian materi, pemberian materi melalui slide power point, post-test evaluasi, dan penutupan. Instrumen dalam memberikan materi adalah power point, untuk melakuakan pre-test dan post-test menggunakan angket. Luaran yang ingin dicapai adalah guru dan orang tua membuat media Cergam (Cerita Bergambar) serta mempraktikkan dan menerapkan melalui media Cergam sehingga dapat meningkatkan minat membaca anak. Gap analysis PkM yaitu meminimalisir kebutuhan Calistung melalui strategi membaca menyenangkan berbantu media Cergam. Hasil pengabdian diperoleh nilai pre-test sejumlah 15% dan meningkat pada nilai post-test menjadi 100%, kenaikan nilai dari sebelum dan sesudah pemberian materi menunjukkan bahwa pemberian penyuluhan berhasil menambah pengetahuan bagi guru dan orang tua bimbingan belajar Ilman Nafi’.
Optimising global conservation, restoration, and agriculture for people and nature
Authors: Duarte Gabriela , Krieger Joana , Capellão Renata , Lacerda Eduardo , Mortara Sara , Rocha Diogo , Oliveira Luiz Gustavo , Iribarrem Alvaro , Gomes Fernanda , Brooks Thomas , Chaplin-Kramer Rebecca , Enquist Brian , Feng Xiao , Hannah Lee , Hill Samantha , Leclère David , Merow Cory , Obersteiner Michael , Roehrdanz Patrick , Sharp Richard , Watson James , Loyola Rafael , Strassburg Bernardo 
Published: September 2023

Abstract
The Kunming-Montreal Global Biodiversity Framework is a worldwide plan to urgently address and reverse biodiversity loss, intending to achieve a harmonious relationship between humanity and nature by 2050. This paper seeks to contribute to operationalising the framework, specifically concerning biodiversity conservation and nature's contributions to people. Using a global analytical approach, we identify optimised areas for conservation, restoration and agriculture, considering food production, urban expansion, population growth, and climate change projections. By formulating scenarios for increasing natural areas enabled by improvements in agricultural productivity and trade, and considering local and global constraints on restoration actions, we analyse potential outcomes for biodiversity and people. Our findings demonstrate that an optimised spatial allocation of land use could substantially mitigate projected negative impacts and even surpass the current situation, leading to significant socio-environmental gains. However, the best global scenarios for nature and people require integrated planning that considers mitigating climate change, reducing human pressure on natural habitats, increasing trade, and changing human behaviour. Aligning efforts to protect and restore nature with broader sustainability goals through coordinated and transformative action is central to implement the Global Biodiversity Framework and delivery of a more sustainable future.
Box-Behnken design in optimizing heavy metal removal from wastewater using selenium hybridized graphitic carbon nitride nanocomposites
Authors: Mohamed Yasser , Elgohary Elzahraa , Nazer Hossam A. El 
Published: September 2023

Abstract
In this study Box–Behnken designs and response surface methodology (BBD-RSM) was used for optimizing heavy metal adsorption. The hazardous effect of wastewater on agriculture, animals and human as well makes its remediation is being considered a global challenge. Herein, a novel visible-light-responsive selenium-doped graphitic carbon nitride composites via the exfoliation of g-C3N4 polymer with different concentrations of selenium precursor (1w%, 2.5w%, 5w%, with respect to the weight of g-C3N4) under ultrasound irradiation condition to produce the hybridized the corresponding polymeric nanocomposites (5%Se/g-C3N4), (10%Se/g-C3N4) and (25%Se/g-C3N4) denoted names C1, C2, C3; respectively. Full chracterization for the nanocomposites was performed using scanning electron microscope (SEM), X-ray diffraction (XRD), UV-Vis diffuse reflection spectroscopy. The as-prepared nanocomposites compared to pure g-C3N4 were applied in wastewater treatment for a real sample collected from Siwa Lake that suffered from increasing the heavy metal ions due to industrial drainage. Testing the catalytic activity of the prepared composites in treatment of wastewater sample collected from Siwa Lake in Egypt affected by the industrial drainage that was analyzed to determine the occurred polluted heavy metal ions. It was indicated that this sample contained Ca(II), Zn(II), Fe(II), Cu(II), Mn(II) and Cd(II) ions. The metal adsorption measurements were developed using atomic absorption spectroscopy (AAS) to show the removal efficiency of metal ions.
Hybrid DEA-BW-KEMIRA Approach for Multiple Attribute Decision-Making: A Weighted Analysis Perspective
Authors: Soltanifar Mehdi 
Published: September 2023

Abstract

This study presents a novel hybrid approach for Multiple Attribute Decision-Making (MADM), integrating the Data Envelopment Analysis (DEA), Best Worst Method (BWM), and KEmeny Median Indicator Ranks Accordance (KEMIRA) methods. The proposed approach utilizes DEA to streamline the weight selection process in decision-making. By combining BWM and KEMIRA, the hybrid approach improves the accuracy and efficiency of attribute ranking and decision-making. Empirical results demonstrate the effectiveness of the proposed approach in addressing MADM problems with multiple attributes. The weighted analysis perspective provided by this hybrid approach offers valuable insights into decision-making processes, assisting decision makers in making informed choices. This research contributes to the advancement of MADM methodologies and introduces a new approach for handling complex decision scenarios.
PAWS: A Synergy-Based Robotic Quadruped Leveraging Passivity for Robustness and Behavioural Diversity
Authors: Stella Francesco , Achkar Mickael , Santina Cosimo Della , Hughes Josie 
Published: September 2023

Abstract
Quadrupedal animals show remarkable capabilities in traversing diverse terrains and display a range of behaviors and gait patterns. Achieving similar performance is a key goal for robotics researchers. We propose a bio-inspired approach to the design of quadrupeds that seeks to exploit the body and the passive properties of the robot. Using this novel approach we develop \textit{PAWS}, a Passive Automata With Synergies. By leveraging the principles of motor synergies, the design incorporates variable stiffness, biological anatomical insights, and self-organization to simplify control while maximizing its capabilities. The resulting synergy-based quadruped requires only four actuators and exhibits emergent, animal-like dynamical responses, including robustness to environmental perturbations and a wide range of behaviors. The finding contributes to the development of machine intelligence, and provides robots with more efficient and natural-looking robotic locomotion by combining synergistic actuation, compliant body properties, and embodied compensatory strategies.
Theory of resonantly enhanced photo-induced superconductivity
Authors: Michael Marios , Eckhardt Christian , Chattopadhyay Sambuddha , Kennes Dante , Demler Eugene , Sentef Michael 
Published: September 2023

Abstract
Optical driving of materials has emerged as a versatile tool to control their properties, with photo-induced superconductivity being among the most fascinating examples. In this work, we show that light or lattice vibrations coupled to an electronic interband transition naturally give rise to electron-electron
attraction that may be enhanced when the underlying boson is driven into a non-thermal state. We find this phenomenon to be resonantly amplified when tuning the boson’s frequency close to the energy difference between the two electronic bands. This result offers a simple microscopic mechanism for photo-induced superconductivity and provides a recipe for designing new platforms in which light-induced superconductivity can be realized. We propose a concrete setup consisting of a graphene hBN-SrTiO3 heterostructure, for which we estimate a superconducting Tc that may be achieved upon driving the system.
Caveolin-1 restrains pathogenic T follicular helper cell response in primary Sjögren’s syndrome
Authors: Lin Xiang , Yu Sulan , Wu Meiling , Zeng Weizhen , Fu Weiwei , Chen Yacun , Xie Jing , Li Philip , Feng Yun , Shen Jiangang 
Published: September 2023

Abstract
T follicular helper (Tfh) cells play a central role in humoral autoimmunity, including primary Sjögren’s syndrome (pSS). However, targeting Tfh cells is challenging in clinical management. Previous studies suggested inducible T­cell co­stimulator (ICOS) directed Tfh cell motility in engaging bystander B cells. Here, we identified a novel function of caveolin-1 (Cav-1) in restraining Tfh cell motility, in which Icos transcription was repressed by peroxisome proliferator-activated receptor alpha (PPARα), unexpectedly, independence of lipid metabolism. In the context of autoimmunity, Cav-1 and PPARα expressions were decreased in CD4+ T cells from pSS patients and mice with experimental SS (ESS), while Cav-1 deficiency significantly exacerbated Tfh cell response and ESS pathology. Importantly, pharmaceutical activation of PPARα with fenofibrate effectively ameliorated ESS in mice with acute or chronic inflammation. These results revealed an unrecognized role of Cav-1/PPARα axis in Tfh cell tolerance, suggesting PPARα as a promising target in the treatment of humoral autoimmunity.
Catalytic Enantioselective Primary C-H Borylation for Acyclic All-carbon Quaternary Stereocenters
Authors: Xu Senmiao , Yang Yuhuan , Chen Jingyao , Shi Yongjia , Liu Peizhi , Feng Yuxiang , Peng Qian 
Published: September 2023

Abstract
Creating a perfect catalyst to operate enzyme-like chiral recognition is a long-sought aim. A challenging example in this context is constructing acyclic all-carbon quaternary stereogenic centers by transition-metal catalyzed enantioselective C-H activation. We now report highly enantioselective iridium-catalyzed primary C-H borylation of α-all-carbon substituted 2,2-dimethyl amides enabled by a tailor-made chiral bidentate boryl ligand (CBL). The success of the current transformation attributes to CBL/iridium catalyst with a confined chiral pocket. This protocol provides a diverse array of acyclic all-carbon quaternary stereocenters with excellent enantiocontrol and distinct structural features. Computational study reveals that steric hindrance of CBL could regulate the type of dominant orbital interaction between the catalyst and the substrate, which is crucial to conferring high chiral induction.
Individual in-situ GPS-derived acceleration-speed profiling: towards automatization and refinement
Authors: Miguens Nathan , Brocherie Franck , Moulié Loïc , Milhet Patrick , Bon Mathieu , Lassus Pierre , Toussaint Jean-François , Sedeaud Adrien 
Published: September 2023

Abstract
Background:
Recently a proof-of-concept was proposed to derive the soccer players’ individual in-situ acceleration-speed (AS) profile from global positioning system (GPS) data collected over several sessions. The present study aimed to validate an automatized method of individual GPS-derived in-situ AS profiling in professional rugby union setting.
Method:
AS profiles of forty-nine male professional rugby union players representing 61.5 million positions, from which acceleration was derived from speed during 51 training sessions and 11 official games, were analyzed. A density-based clustering algorithm was applied to identify outlier points. Multiple AS linear relationships were modeled for each player and session, generating numerous theoretical maximal acceleration (A0), theoretical maximal running speed (S0) and AS slope (ASslope, i.e., overall orientation of the AS profile). Each average provides information on the most relevant value while the standard deviation denotes the method accuracy. In order to assess the reliability of the AS profile within the data collection period, data were compared over two 2-weeks phases by the inter-class correlation coefficient. A0 and S0 between positions and type of sessions (trainings and games) were compared using ANOVA and post hoc tests when the significant threshold had been reached.
Results:
All AS individual profiles show linear trends with high coefficient of determination (r² > 0.81). Good reliability (Inter-class Correlation Coefficient range between 0.92, to 0.72) was observed between AS profiles, when determined 2 weeks apart for each player. AS profiles depend on players’ positions, types of training and games. Training and games data highlight that highest A0 are obtained during games, while greatest S0 are attained during speed sessions.
Conclusions:
This study provides individual in-situ GPS-derived AS profiles with automatization capability. The method calculates an error of measurement for A0 and S0, of paramount importance in order to improve their daily use. The AS profile differences between training, games and playing positions open several perspectives for performance testing, training monitoring, injury prevention and return-to-sport sequences in professional rugby union, with possible transferability in other sprint-based sports.
TLR-2 derangements likely play a significant role in the inflammatory response and thrombosis in patients with Ph(-) classical myeloproliferative neoplasm
Authors: Wang Jen Chin , Shi Guanfang , Chen Chi , Wong Ching , Gotlieb Vladimir , Boyapat Lakshmi i , Sun Lithi , Nair Kiron 
Published: September 2023

Abstract
This study investigated TLRs on inflammatory pathways in Ph(-)MPNs. The results showed that TLR2 were increased in PV and MPN (PV + ET + MF), while TLR4 were only increased in MPN. TLR3, 7, and 9 were not elevated. We further cultured mdDC cells and demonstrating TLR2 elevated (TLR-E) patients secreted more cytokines than TLR2 normal (TLR-N), confirming the importance of TLR2. S100A9 and ROS were also measured, revealing S100A9 levels were increased in PV, MF, and MPN, while ROS levels increased only in MF and not in PV or ET. This data suggests that the pathogenesis of MPNs initially involves TLR2, minorly fromTLR4, along with S100A9 then induce ROS formation, JAK2 mutation,, leading ET and PV evolved into MF or leukemia. Further analysis of the data and studies, we found. 1) patients with Jak2 mutations or leukocytosis exhibited higher TLR2 expression, 2) cells from MPN patients displayed a stronger response to PM3CSK4 (TLR2 agonist) in leukocyte-platelet interaction compared to LPS ( TLR4 agonist). Adding TLR-2 inhibitor (not TLR-4 inhibitor) significantly attenuated this response, 3) TLR2-E patients experienced more thrombosis (29%) than TLR2-N (19%). These findings also suggest TLR2 plays a significant role in thrombosis in MPN.
Electrolytic cement clinker production sustained through orthogonalization of ion vectors
Authors: Berlinguette Curtis , Zhang Zishuai , Mowbray Benjamin , Parkyn Colin , Kim Yongwook , Ji Tengxiao , Ren Shaoxuan 
Published: September 2023

Abstract
Electrochemical reactors can reduce the carbon intensity of cement production by using electricity to convert limestone (CaCO3) into Ca(OH)2, which can be converted into cement clinker by reacting t with silica (SiO2) at high temperatures. A key challenge with this method is that the deposition of solid Ca(OH)2 at the membrane leads to unacceptably low energy efficiencies. To address this challenge, we connected the electrochemical reactor (“cement electrolyser”) to a distinctive chemical reactor (“calcium reactor”) so that Ca(OH)2 could form there instead of forming within the electrochemical reactor. In this tandem system, the cement electrolyser generates H+ and OH– in the respective chemical and cathode compartments. The H+ then reacts with CaCO3 to form Ca2+ ions, which are diverted into the calcium reactor to react with the OH– to form Ca(OH)2. We fabricated a composite membrane to selectively block the transport of Ca2+ into the cathode compartment. Charge balance in the cement reactor was enabled with monovalent ions (e.g., K+) as the positive charge carrier. This orthogonalized ion management was validated by operando imaging. The tandem reactor enabled the electrolysis process to operate for 50 hours at 100 mA cm-2 without any voltage increase, which represents a meaningful step forward for electrochemical cement clinker precursor production.