bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-dependent vestibular cingulate–cerebral network underlying gravitational perception: a cross-sectional multimodal study
Authors: Plute Tritan J. , Spencer Dennis D. , Alkawadri Rafeed 
Published: December 2022

AbstractBackground and objectivesThe cingulate gyrus (CG) is a frequently studied yet not wholly understood area of the human cerebrum. Previous studies have implicated CG in different adaptive cognitive–emotional functions and fascinating or debilitating symptoms. We describe an unusual loss of gravity perception/floating sensation in consecutive persons with drug-resistant epilepsy undergoing electrical cortical stimulation (ECS), network analysis, and network robustness mapping.MethodsUsing Intracranial–EEG, Granger causality analysis, cortico-cortical evoked potentials, and fMRI, we explicate the functional networks arising from this phenomenon's anterior, middle, and posterior cingulate cortex.ResultsFifty-four icEEG cases from 2013 to 2019 were screened. In 40.7% of cases, CG was sampled and in 22.2% the sampling was bilateral. ECS mapping was carried out in 18.5% of the entire cohort and 45.4% of the cingulate sampled cases. Five of the ten CG cases experienced symptoms during stimulation. A total of 1942 electrodes were implanted with a median number of 182 electrode contacts per patient (range: 106–274). The electrode contacts sampled all major cortex regions. Sixty-three contacts were within CG. Of those, 26 were electrically stimulated; 53.8% of the stimulated contacts produced positive responses, whereas 46.2% produced no observable responses. Our study reports a unique perceptive phenomenon of a subjective sense of weightlessness/floating sensation triggered by anterior and posterior CG stimulation, in 30% of cases and 21.42% of electrode stimulation sites. Notable findings include functional connections between the insula, the posterior and anterior cingulate cortex, and networks between the middle cingulate and the frontal and temporal lobes and the cerebellum. We also postulate a vestibular–cerebral–cingulate network responsible for the perception of gravity while suggesting that cingulate functional connectivity follows a long-term developmental trajectory as indicated by a robust, positive correlation with age and the extent of Granger connectivity (r = 0.82,p = 0.0035).DiscussionWe propose, in conjunction with ECS techniques, that a better understanding of the underlying gravity perception networks can lead to promising neuromodulatory clinical applications.Classification of evidenceThis study provides Class II evidence for CG's involvement in the higher order processing of gravity perception and related actions.
Confocal imaging of biomarkers at a single-cell resolution: quantifying 'living' in 3D-printable engineered living material based on Pluronic F-127 and yeast
Saccharomyces cerevisiae
Authors: Žunar Bojan , Ito Taiga , Mosrin Christine , Sugahara Yoshiyuki , Bénédetti Hélène , Guégan Régis , Vallée Béatrice 
Published: December 2022

Abstract

Background
Engineered living materials (ELMs) combine living cells with non-living scaffolds to obtain life-like characteristics, such as biosensing, growth, and self-repair. Some ELMs can be 3D-printed and are called bioinks, and their scaffolds are mostly hydrogel-based. One such scaffold is polymer Pluronic F127, a liquid at 4 °C but a biocompatible hydrogel at room temperature. In such thermally-reversible hydrogel, the microorganism-hydrogel interactions remain uncharacterized, making truly durable 3D-bioprinted ELMs elusive.

Methods
We demonstrate the methodology to assess cell-scaffold interactions by characterizing intact alive yeast cells in cross-linked F127-based hydrogels, using genetically encoded ratiometric biosensors to measure intracellular ATP and cytosolic pH at a single-cell level through confocal imaging.

Results
When embedded in hydrogel, cells were ATP-rich, in exponential or stationary phase, and assembled into microcolonies, which sometimes merged into larger superstructures. The hydrogels supported (micro)aerobic conditions and induced a nutrient gradient that limited microcolony size. External compounds could diffuse at least 2.7 mm into the hydrogels, although for optimal yeast growth bioprinted structures should be thinner than 0.6 mm. Moreover, the hydrogels could carry whole-cell copper biosensors, shielding them from contaminations and providing them with nutrients.

Conclusions
F127-based hydrogels are promising scaffolds for 3D-bioprinted ELMs, supporting a heterogeneous cell population primarily shaped by nutrient availability.

Graphical Abstract
Microsurgery for vestibular schwannoma: analysis of short-term clinical outcome
Authors: Wang Xu , Li Mingchu , Xiao Xinru , Chen Ge , Tang Jie , Lin Qingtang , Guo Hongchuan , Song Gang , Wu Xiaolong , Bao Yuhai , Liang Jiantao 
Published: December 2022

Abstract
Background
Total removal of the vestibular schwannoma when preserving the function of the facial nerve is difficult. The objective of the current study was to investigate the short-term clinical outcome of vestibular schwannoma removal via retro-sigmoid approach.

Methods
One-hundred consecutive patients diagnosed with vestibular schwannoma were surgically treated between December 2018 and August 2019 in Xuanwu Hospital, Capital Medical University. The clinical classification, surgical position, gross total removal rate, the anatomical and functional preservation rates of facial nerve, and the postoperative complications were retrospectively analyzed.

Results
All 100 patients including 34 males and 66 females were operated on via retro-sigmoid approach. According to Koos vestibular schwannoma grading system, 18 cases were grade 2, 34 cases were grade 3, and 48 cases were grade 4. According to Hannover vestibular schwannoma grading system, 5 cases were T2, 6 cases were T3a, 8 cases were T3b, 30 cases were T4a, and 51 cases were T4b. Seventy-three surgeries were performed under lateral position, and 27 cases were operated under semi-sitting position. The gross total removal rate was 90.0%; the anatomic reservation rate of the facial nerve was 96.0%. According to the House-Brackman system, the facial nerve function was grades 1–2 in 78.0% cases, grade 3 in 7.0% cases, and grades 4–5 in 15% cases. For patients with effective hearing before operation, the hearing reservation rate was 19.0%. Two patients (2.0%) developed intracranial hematoma after operation.

Conclusion
Most vestibular schwannoma could be completely removed with good postoperative facial nerve function. If total removal of tumor is difficult, we should give priority to the functional preservation of the nerve function.
Study of changes in cardiac output, stroke volume, and cardiac index with two doses of mannitol infusion during supratentorial craniotomy
Authors: Ray Pawan Kumar , Malviya Deepak , Harjai Mamta , Tripathi Manoj , Singh Deepak Kumar , Mishra Smarika 
Published: December 2022

Abstract
Background
Mannitol is used extensively in supratentorial surgeries to reduce intracranial pressure. The optimum dose of mannitol is still a matter of debate. We have done this prospective, comparative and randomized study to compare the changes in cardiac output (CO), stroke volume (SV), cardiac index (CI), central venous pressure (CVP), brain relaxation, and side effects in two doses of mannitol infusion. We have divided 60 enrolled patients randomly into two groups. We infused 0.7gm kg-1, 20% mannitol in 20 min duration in Group A and 1.4gm kg-1 of 20% mannitol in 20 min in Group B. Flotrac transducer was connected to assess SV, CO, and CI. We recorded and analyzed brain relaxation score, HR, MAP, CVP, SV, CO, and CI at predefined time intervals after mannitol infusion. Chi-square test and unpaired t test were used to analyze categorical and continuous variables between two groups.

Results
We have found statistically significant and better brain relaxation in Group B than Group A. Significant (p<0.05) difference in CVP was found between the groups at 10, 20 min after start of infusion, and 5, 10, and 15 min after termination of infusion. We found significant (p<0.05) difference in SV, CO, and CI between the groups at most of the time periods.

Conclusions
We can conclude that higher dose of mannitol provides better brain relaxation intraoperatively without significant adverse effects. We assessed more changes in hemodynamic and cardiac parameters with higher dose of mannitol that did not cause clinical deterioration.
Can electric vehicles be an alternative for traditional fossil-fuel cars with the help of renewable energy sources towards energy sustainability achievement?
Authors: Al-Ghaili Abbas M. , Kasim Hairoladenan , Aris Hazleen , Al-Hada Naif M. 
Published: December 2022

AbstractThe use of conventional fossil-fuel vehicles in the transportation industry contributes to climate change. The energy producing sector has actually adjusted its strategy to utilize more renewable energy to satisfy the energy demand as a result of this change in strategy. The use of electric vehicles (EVs) in the transportation network has also helped to reduce pollution from the energy industry. However, the distribution network would be placed under a lot of stress if a lot of EVs are attached to it, which might cause a number of problems and worries. However, several initiatives have been made in this direction to help find answers to these issues. The contribution of this review article is that, a number of the benefits of using the employed EVs techniques for the purpose of utilizing renewable energy sources (RESs) towards the accomplishment of a sustainable energy goal for a green environment in the so foreseeable have been highlighted; aiming to provide a larger variety of readers insights and suggestions for future research development. There have been a number of studies that have recommended various ideas and strategies for a reliable renewable energy supply. Their findings have been published in scientific journals. But the relationship between RESs and EVs in terms of energy efficiency is still needed to be further investigated to shorten such a gap in order to assess how EVs can help RESs achieve energy sustainability. Besides, the purpose of this study is to identify and assess the most recent advances and methodologies in the field. It's been possible to use numerous EV technologies to help with various problems and challenges, including the need for quick EV charging stations. However, there is a worry over the viability and applicability of EV-applied technologies that are ideally suited towards greater and more efficient usage of RESs in order to either attain or contribute to energy sustainability. In this article, we will discuss a variety of EV technologies that have been used in the past and contributed to the development of RESs. The method has applied the PRISMA 2020 strategy for inclusion and exclusion criteria. Also, the method has used specific keyword related to the topic including "electric vehicles" and "renewable energy sources". It is found that EVs can be an effective alternative for currently used fossil-fuel vehicles due to a set of reasons highlighted in this review including fast EV charging stations, efficient design for PV solar panels, and effective utilization of RESs.
Identification and classification of heat pump problems in the field and their implication for a user-centric problem recognition
Authors: Weigert Andreas 
Published: December 2022

AbstractHeat pumps are at the heart of the transition to sustainable heating in buildings. Yet, minor installation and setting errors add to unnoticed performance drops over the system’s lifetime. With the advent of smart meters that constantly measure electricity consumption, data patterns of heat pumps have become available, even for the many not connected to the Internet. These data hold the potential to monitor heat pumps continuously, identify issues, and thus assist energy consultants and heat pump owners in lifting hidden conservation potential. Yet, research and practice lack an overview of specific problems that could help in this task. In a mixed-method approach, this study investigated 228 protocols of on-site heat pump inspections in Switzerland and found 47 problem classes with varying frequencies. Based on this empirical data and expert interviews, a classification scheme for heat pump issues is proposed and validated. It uncovers the cause of problems, how and by whom they can be recognised and solved, and potential benefits. The work demonstrates that (i) several problems are likely to create smart meter patterns and that (ii) heat pump owners could be involved in the problem recognition and solving process if they get guidance (i.e. simple rules and instructions). Finally, this study discusses implications for developing information systems to automate and assist the recognition and solving of problems. Such information systems may raise not only the attention of heat pump owners but also trigger desired actions (i.e. request consultancy, inspect heat pump themselves).
Tri-modality therapy in advanced esophageal carcinoma: long-term results and insights from a developing world, institutional cohort
Authors: Chufal Kundan Singh , Ahmad Irfan , Bajpai Ram , Miller Alexis Andrew , Chowdhary Rahul Lal , Makker Jasbir , Batra Ullas , Nathany Shrinidhi , Sharief Muhammed Ismail , Umesh Preetha , Sharma Mansi , Amrith Patel , Pahuja Anjali Kakria , Sethi Jaskaran , Antony Varghese , Gairola Munish 
Published: December 2022

Objective: To evaluate treatment outcomes in patients from a low-middle income country (LMIC) with esophageal carcinoma who underwent esophagectomy after neoadjuvant chemoradiation (NACRT/S). Methods: Between 2010 and 2020, 254 patients (median follow-up: 53 months) met our inclusion criteria. Out-of-field nodal regions were determined by reviewing individual radiotherapy plans. Cox regression modelling was performed to analyze overall survival (OS) and recurrence-free survival (RFS), while pathological complete response (pCR) prediction utilized Poisson regression. Results: The median OS was 71.4 months (interquartile range: 19.6–∞), RFS did not reach the median and pCR rate was 46%. On multivariable Cox regression, BMI [0.93 (0.89–0.98); 0.94 (0.89–0.99)] and absence of out-of-field node with extranodal extension (ENE)[0.22 (0.09–0.53); 0.30 (0.12–0.75)] influenced OS and RFS, respectively. Age [1.03 (1.01–1.06)], nodal stage [cN2-3 vs cN0: 2.67 (1.08–6.57)] and adventitial involvement [2.54 (1.36–4.72)] also influenced OS, while involved margins [3.12 (1.24–7.81)] influenced RFS. On multivariable Poisson regression, non-CROSS-chemotherapy regimens [0.65 (0.44–0.95)] and residual primary disease on pre-surgical imaging [0.73 (0.57–0.93)] were significantly associated with pCR. The most frequently involved in-field and out-of-field nodal regions were the periesophageal and perigastric (greater and lesser curvature) regions, respectively. Conclusion: NACRT/S is feasible and effective in patients from LMIC. Out-of-field ENE merits further investigation as a prognostic factor since it significantly influenced both OS and RFS. Advances in knowledge: The results of clinical trials are replicable in LMICs. Out-of-field ENE is an independent prognostic factor for OS and RFS.
Εμπλοκή γονέων και σχολική επίδοση παιδιών
Authors: Μηκέ Παναγιώτα 
Published: December 2022

Τις τελευταίες δύο δεκαετίες έχουν διεξαχθεί πολλές έρευνες με αντικείμενο μελέτης την εμπλοκή των γονέων στη σχολική επίδοση των παιδιών. Παράλληλα, έχουν προταθεί θεωρητικά μοντέλα που αναδεικνύουν τη σημασία της γονεϊκής εμπλοκής στην επιτυχημένη πορεία του παιδιού στο σχολείο [3]. Στόχος της παρούσας εργασίας είναι να περιγράψει: α) τις ερμηνείες που έχουν αποδοθεί από τους ερευνητές στις έννοιες γονεϊκή εμπλοκή, κίνητρα, σχολική επιτυχία και επίδοση β) τις σύγχρονες θεωρίες, που ερμηνεύουν τη σχέση που αναπτύσσεται μεταξύ της γονεϊκής εμπλοκής και της σχολικής επίδοσης των παιδιών και γ) τους παράγοντες που επηρεάζουν την πολύπλοκη αυτή σχέση.
The effects of antiretroviral stockout on primary health care nurses in the Ethekwini and Ilembe districts, KwaZulu-Natal
Authors: Mahomed Farhana , Gumede Emelda Zandile 
Published: December 2022

Background: Nurses face challenges of antiretroviral therapy (ART) stock out when rolling out, leading to drug resistance, poor compliance and decreased viral suppression. Poor viral suppression leads to higher morbidity and mortality rates, hence a need to strengthen supply chain principles in order to achieve equal distribution of resources amongst clinics. Nurses also need to have relevant guidelines available to prevent treatment failure. The study aimed to describe the effects of ART stockouts on primary health nurses rolling out ART in clinics in KwaZulu Natal. Methods: The study followed a qualitative approach, using a descriptive design. Two primary healthcare clinics in Ilembe and Ethekwini districts were selected for the study. The population comprised of 8 purposively selected participants. In-depth interviews and focus groups were conducted to describe the experiences of primary health care nurses rolling out antiretroviral therapy regarding stockout and how it was managed. Data collection and analysis followed Yates, Partridge and Bruce steps. Ethics and trustworthiness were maintained. Results: The singular theme of inconsistent availability of treatment emerged, as well as sub-themes of means used to manage treatment stockout and supply change management issues. Conclusions: An adequate supply of ART through an efficient supply chain management strategy, ongoing training in primary health care and nurse-initiated management of antiretroviral therapy and the availability of treatment guidelines should be enforced.
Systematic review: Safety of surgical male circumcision in context of HIV prevention public health programmes
Authors: Jindai Kazuaki , Farley Tim , Awori Quentin , Temu Anaelia-Siya , Ndenzako Fabian , Samuelson Julia 
Published: December 2022

Background: Since the recommendation of voluntary medical male circumcision (VMMC) to reduce the risk of heterosexually acquired HIV, a number of adolescent boys and men in 15 priority countries in Africa have been circumcised. Our primary goal was to identify the incidence of adverse events (AEs) associated with VMMC and to assess the safety profile among adolescent boys 10 – 14 years. Methods: We searched the databases MEDLINE and Embase, WHO, and conference abstracts from 2005 to 2019. The incidence of AEs was estimated by type of AE, size of study and age. Results: We retained 40 studies. Severe and moderate AEs overall were estimated at 0.30 per 100 VMMC clients with wide variability per study type. A higher rate was noted in small and moderate scale programmes and device method research studies compared with larger scale programmes. There was a limited number of studies reporting AEs among younger adolescent boys and they had higher infection-related AEs than those aged 20 years and older. Case studies noted rare AEs such as necrotizing fasciitis, tetanus, and glans injury. Conclusions: AE rates were comparable to those from the randomized controlled trials (RCTs) that led to recommendations and implementation of VMMC in high HIV burden countries, despite being implemented in low resource settings. Clients over time have increasingly included adolescents under the age of 15 years. Studies suggest potentially higher risks in this age group. As VMMC services are sustained, patient safety surveillance systems and promoting a patient safety culture are crucial to identify and mitigate potential harms from medical male circumcision.
Justification of the Need for Reengineering of Business Processes at Enterprises of the Russian Fuel and Energy Sector
Authors: Temukuev T. 
Published: December 2022

The article considers the application of the process approach in the management of enterprises of the fuel and energy complex. In conditions when the fuel and energy sector plays a key role in the economy of a country like Russia, with increased uncertainty and complexity of forecasting changes in the external environment, it is necessary to develop new approaches to managing business processes in this area. The rapid transformation of the global balance in the energy market, the redistribution of forces and gravity points taking place at the moment, set new development goals for the entire industry as a whole and for individual companies. We should not lose sight of the sanctions pressure caused by the escalated political confrontation between Russia and Western countries.
It is proposed to identify key business processes at fuel and energy complex enterprises and to justify methodological approaches to their reengineering, taking into account the specifics of the industry and the need for a qualitative change in the behavior model of fuel and energy complex enterprises in new macroeconomic conditions.
PENGARUH KUALITAS PRODUK, HARGA, DAN PROMOSI TERHADAP KEPUTUSAN PEMBELIAN
Authors: Rukmayanti Rukmayanti , Fitriana Fitriana 
Published: December 2022

The purpose of this study is to determine the effect of product quality, price, and promotion on purchasing decisions for MS Glow product. This study used primary data with a number of samples of 100 respondents. Data analysis methods used include validity tests, reliability tests, multiple linear regression analyses, and hypothesis testing. The results of the data analysis indicate that product quality have a positive effect on purchasing decisions, promotion have a positive effect on purchasing decisions, and price have a negative but no significant effect on purchasing decisions.
Un treball important sobre la Societat Econòmica Barcelonesa d’Amics del País
Authors: Ghanime Albert 
Published: December 2022

Ressenya de:
Albert Balcells, Compromís i progrés: La Societat Econòmica Barcelonesad’Amics del País. Vol. I, Del 1822 al 1874, Barcelona, Editec,2021.Albert Balcells, Compromís i progrés: La Societat Econòmica Barcelonesad’Amics del País. Vol. II, Del 1875 als temps recents, Barcelona,Editec, 2019.
Problematitzant els feminismes islàmics
Authors: Traidi Aida 
Published: December 2022

Els feminismes islàmics argumenten que el missatge de la revelació alcorànica és garant dels drets de les dones. Aquest article discuteix els feminismes islàmics com a doble resistència: a les estructures colonials i als discursos patriarcals construïts en nom de l'islam. Pel que fa a les assumpcions orientalistes d’Occident, es qüestiona el domini de les estratègies dels feminismes hegemònics com a única forma d’emancipació vàlida. Quant a les estructures patriarcals islàmiques, es qüestiona tota la jurisprudència elaborada des d’un punt de vista masculí. Lamrabet (2017) considera que el missatge original de l'islam ha estat distorsionat a causa del monopoli del coneixement religiós per part dels homes, que han fet una interpretació patriarcal que ha marginat el rol de la dona. Segons Grosfoguel (2014) i Adlbi (2017), hi ha hagut una distorsió colonial de la tradició musulmana que ha modificat aspectes de la mateixa teologia islàmica. En el cas del hijab, els imperis colonials han assumit un discurs de salvació. Alhora, algunes nocions islàmiques contemporànies del hijab redueixen tota l'ètica global de l'Alcorà al concepte del hijab. Quins espais han d'ocupar els feminismes islàmics? No totes les propostes que proporcionen són decolonials. Sovint no han aconseguit analitzar l'alliberament en els seus propis termes, fet que ha donat com a resultat reproduir les narratives definides per les normes hegemòniques de les societats occidentals. L'anàlisi de les propostes dels feminismes islàmics contribueix a examinar com poden transcendir l'àmbit del discurs i respondre a l'expressió de les aspiracions en termes autodefinits, reinterpretant el significat de les fonts sagrades de l'islam des d'una perspectiva de gènere amb l'objectiu de trobar l'esperit emancipatori del missatge espiritual de l'islam.
PARAULES CLAU: feminismes islàmics; hijab; interseccionalitat; decolonialitat; patriarcat.