bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subconcussion revealed by sound processing in the brain
Authors: Kraus Nina , Colegrove Danielle , Otto-Meyer Rembrandt , Bonacina Silvia , Nicol Trent , Cunningham Jenna , Krizman Jennifer 
Published: June 2023

ABSTRACT

Introduction/Purpose
We tested the hypothesis that an objective measure of auditory processing reveals a history of head trauma that does not meet the clinical definition of concussion.

Methods
Division I collegiate student-athletes (n = 709) across 19 sports were divided into groups, based on their sport, using prevailing classifications of “contact” (317 males, 212 females) and “noncontact” (58 males, 122 females). Participants were evaluated using the frequency-following response (FFR) to speech. The amplitude of FFR activity in a frequency band corresponding to the fundamental frequency (F0)—the voice pitch—of the speech stimulus, an outcome reduced in individuals with concussions, was critically examined.

Results
We found main effects of contact level and sex. The FFR-F0 was smaller in contact athletes than noncontact athletes and larger in females than males. There was a contact by sex interaction, with the FFR-F0 of males in the contact group being smaller than the three other groups. Secondary analyses found a correlation between FFR-F0 and length of participation in contact sports in male athletes.

Conclusion
These findings suggest that the disruption of sensory processing in the brain can be observed in individuals without a concussion but whose sport features regular physical contact. This evidence identifies sound processing in the brain as an objective marker of subconcussion in athletes.
Η διαταραχή αυτιστικού φάσματος στο σύγχρονο κινηματογράφο: Κινηματογραφικές αναπαραστάσεις σύμφωνα με τα διαγνωστικά χαρακτηριστικά του DSM- V
Authors: Αντώνογλου Μαρία , Σοφός Αλιβίζος (Λοΐζος) 
Published: June 2023

Οι κινηματογραφικές αναπαραστάσεις των αυτιστικών ατόμων στον κινηματογράφο, υπόκεινται σε συζητήσεις με έντονο ενδιαφέρον τα τελευταία χρόνια. Ο προβληματισμός σχετικά με το αν αυτές οι αναπαραστάσεις είναι ακριβείς ή όχι, σχετίζεται με το ερώτημα αν μπορούν να οδηγήσουν σε στερεότυπες αντιλήψεις σχετικά με την διαταραχή. Σκοπός της παρούσας εργασίας, είναι να μελετήσει εάν οι αναπαραστάσεις ατόμων με διαταραχή αυτιστικού φάσματος, συνάδουν με τα διαγνωστικά κριτήρια του DSM-V. Το νόημα που προκύπτει από τα αποτελέσματα, συζητιέται σε σχέση με την πιθανή εκπαιδευτική αξία που μπορεί να έχουν οι κινηματογραφικές αναπαραστάσεις για το κοινό. Σύμφωνα με τα ευρήματα της μελέτης, οι κινηματογραφικοί χαρακτήρες με ΔΑΦ φαίνεται να πληρούν με ακρίβεια τα διαγνωστικά κριτήρια του DSM-V. Η πλειοψηφία των αναπαραστάσεων αφορά νεαρούς, λευκούς άνδρες, ενώ πολλοί από τους χαρακτήρες παρουσιάζουν ιδιαίτερες δεξιότητες και ταλέντα. Από την μελέτη των αποτελεσμάτων διαπιστώθηκε ότι, παρόλο που τα στερεότυπα που ακολουθούν την διαταραχή ήταν εμφανή στο δείγμα, ο κινηματογράφος θα μπορούσε να έχει και εκπαιδευτικό χαρακτήρα, κυρίως όσο αφορά πληροφόρηση και ευαισθητοποίηση του ευρύτερου κοινού.
Optimization of binding affinities in chemical space with generative pre-trained transformer and deep reinforcement learning
Authors: Xu Xiaopeng , Zhou Juexiao , Zhu Chen , Zhan Qing , Li Zhongxiao , Zhang Ruochi , Wang Yu , Liao Xingyu , Gao Xin 
Published: June 2023

Background: The key challenge in drug discovery is to discover novel compounds with desirable properties. Among the properties, binding affinity to a target is one of the prerequisites and usually evaluated by molecular docking or quantitative structure activity relationship (QSAR) models. Methods: In this study, we developed Simplified molecular input line entry system Generative Pre-trained Transformer with Reinforcement Learning (SGPT-RL), which uses a transformer decoder as the policy network of the reinforcement learning agent to optimize the binding affinity to a target. SGPT-RL was evaluated on the Moses distribution learning benchmark and two goal-directed generation tasks, with Dopamine Receptor D2 (DRD2) and Angiotensin-Converting Enzyme 2 (ACE2) as the targets. Both QSAR model and molecular docking were implemented as the optimization goals in the tasks. The popular Reinvent method was used as the baseline for comparison. Results: The results on Moses benchmark showed that SGPT-RL learned good property distributions and generated molecules with high validity and novelty. On the two goal-directed generation tasks, both SGPT-RL and Reinvent were able to generate valid molecules with improved target scores. The SGPT-RL method achieved better results than Reinvent on the ACE2 task, where molecular docking was used as the optimization goal. Further analysis shows that SGPT-RL learned conserved scaffold patterns during exploration. Conclusions: The superior performance of SGPT-RL in the ACE2 task indicates that it can be applied to the virtual screening process where molecular docking is widely used as the criteria. Besides, the scaffold patterns learned by SGPT-RL during the exploration process can assist chemists to better design and discover novel lead candidates.
Evaluating the Amyloidosis Speakers Bureau: the influence of amyloidosis patients’ narratives on medical students’ knowledge, attitudes, and behavioral intent
Authors: Adebayo Adebanke L. , Rowan Katherine E. , Sanchorawala Vaishali , Boedicker Mackenzie N. , Boedicker Deborah D. 
Published: June 2023

Background: Amyloidosis is a complex multi-systemic disease. Lack of knowledge about amyloidosis and subsequent mis- or under-diagnosis are major obstacles to treatment, which result in life-threatening organ damage, morbidity, and mortality. Hence, the purpose of this study is to explore the effectiveness of amyloidosis patients’ narratives on medical students. Methods: The Amyloidosis Speakers Bureau (ASB) arranges for amyloidosis patients to speak about their diagnostic and treatment experiences with medical students. Using a randomized post-test only experiment, we compared the effectiveness of patients’ narratives between two groups (treatment and control). Outcome measures included medical students’ intent to actively communicate with patients, acquire knowledge about amyloidosis, and reconsider diagnoses when warranted. Results: The treatment group (those who listened to an ASB patient speaker) had higher mean differences on all measures, including the desire to improve communication with patients, acquire and apply knowledge of amyloidosis, and willingness to reconsider diagnoses when symptoms are puzzling. Conclusions: ASB patient educators widened awareness of an under-diagnosed disease. Listening to a patient’s narrative was associated with positive attitudes toward communication with patients, interest in acquiring and applying knowledge of amyloidosis, and humility about diagnosis. Narrative and persuasion theory are used to explain this quantitative evidence of the power of patient narratives.
Bursztyn od neolitu do wczesnego średniowiecza w zbiorach Muzeum Okręgowego w Toruniu
Authors: Bielińska-Mjewska Beata , Bokiniec Ewa , Uziembło Romualda 
Published: June 2023

Artykuł przedstawia podstawowe dane źródłowe na temat bursztynów przechowywanych w Dziale Archeologii Muzeum Okręgowego w Toruniu, datowanych od neolitu do wczesnego średniowiecza. Informacje te ujęte są w postaci katalogu znalezisk, wraz z krótkim ich omówieniem i dokumentacją rysunkową.
Approximation Benefits of Policy Gradient Methods with Aggregated States
Authors: Russo Daniel 
Published: June 2023

Folklore suggests that policy gradient can be more robust to misspecification than its relative, approximate policy iteration. This paper studies the case of state-aggregated representations, in which the state space is partitioned and either the policy or value function approximation is held constant over partitions. This paper shows a policy gradient method converges to a policy whose regret per period is bounded by ϵ, the largest difference between two elements of the state-action value function belonging to a common partition. With the same representation, both approximate policy iteration and approximate value iteration can produce policies whose per-period regret scales as [Formula: see text], where γ is a discount factor. Faced with inherent approximation error, methods that locally optimize the true decision objective can be far more robust. This paper was accepted by Hamid Nazerzadeh, data science. Supplemental Material: Data are available at https://doi.org/10.1287/mnsc.2023.4788 .
Treatment Effect Risk: Bounds and Inference
Authors: Kallus Nathan 
Published: June 2023

Because the average treatment effect (ATE) measures the change in social welfare, even if positive, there is a risk of negative effect on, say, some 10% of the population. Assessing such risk is difficult, however, because any one individual treatment effect (ITE) is never observed, so the 10% worst-affected cannot be identified, whereas distributional treatment effects only compare the first deciles within each treatment group, which does not correspond to any 10% subpopulation. In this paper, we consider how to nonetheless assess this important risk measure, formalized as the conditional value at risk (CVaR) of the ITE distribution. We leverage the availability of pretreatment covariates and characterize the tightest possible upper and lower bounds on ITE-CVaR given by the covariate-conditional average treatment effect (CATE) function. We then proceed to study how to estimate these bounds efficiently from data and construct confidence intervals. This is challenging even in randomized experiments as it requires understanding the distribution of the unknown CATE function, which can be very complex if we use rich covariates to best control for heterogeneity. We develop a debiasing method that overcomes this and prove it enjoys favorable statistical properties even when CATE and other nuisances are estimated by black box machine learning or even inconsistently. Studying a hypothetical change to French job search counseling services, our bounds and inference demonstrate a small social benefit entails a negative impact on a substantial subpopulation. This paper was accepted by J. George Shanthikumar, data science. Funding: This work was supported by the Division of Information and Intelligent Systems [Grant 1939704]. Supplemental Material: The data files and online appendices are available at https://doi.org/10.1287/mnsc.2023.4819 .
A Scoping Review and Framework of Green Business Models Related to Future Wireless Technology: Bridging Green Business Models to Future Wireless Technology
Authors: Lindgren Peter 
Published: June 2023

There is a growing interest on the profitability and value of Green Business and Green Business Models related to our societies strong push to greening our businesses due to climate change and environmental challenges. Regulation on businesses is everyday getting tighter on different topics of green. Energy and water consumption, type of energy used, greenhouse emissions, waste, use of materials and resources, recycling of materials, collaboration types and latest fulfillment of UN’s 17 world goals. All topics are more or less being related to the term green and in this case green economy, green business, green business models and green technology are seen as solutions to fulfill the green goals and deals.
In this context many business have endeavored willingly or unwillingly to become and adapt the term green. Studies have shown that business however often find it difficult transforming into green. When users and customers and even competitors are not always loyal to those green business offerings and standards a green business and green business model concept have then it becomes even worse to trust and act on the green business vision.
Knowledge and awareness for green business model within the business model communities lacks. Systematic ways and taxonomies to classify and use the term “green” gives the motivation for the study. In this context the paper commence presenting a literature study on the term green business model and relates this to projects on green business and case studies on green business models. The overall research questions discussed are
1. How have and can green business model be defined?
2. How can Future Wireless Technology enhance the evolvement of Green Business Modelling and green business transformation?
The paper seeks to unwrap the different approaches, origin and views available on the term Green Business Model. The paper verifies their success criteria for classifying a green business model and discuss the role wireless technologies plays and can play in operating Green Business Models. The paper ends by proposing a framework to classify the degree of green related to business models.
Experimental demonstration of a nanolaser with a sub-µA threshold current
Authors: Dimopoulos Evangelos , Xiong Meng , Sakanas Aurimas , Marchevsky Andrey , Dong Gaoneng , Yu Yi , Semenova Elizaveta , Mørk Jesper , Yvind Kresten 
Published: June 2023

We demonstrate a nano-buried-heterostructure photonic crystal laser exhibiting an ultralow threshold of 730 nA at telecom wavelengths. This breakthrough was achieved by reducing the doping-induced losses of the laser cavity, enabling the efficient miniaturization of the active region. The laser can be directly modulated at 3 GHz at an energy cost of 1 fJ/bit, and a comparison to longer lasers is given. To the best of our knowledge, this is the lowest threshold reported for any laser operating at room temperature, facilitating on-chip links with ultralow energy consumption.
Thermodynamically limited uncooled infrared detector using an ultra-low mass perforated subwavelength absorber
Authors: Das Avijit , Mah Merlin L. , Hunt John , Talghader Joseph J. 
Published: June 2023

An uncooled detector has reached the thermodynamic temperature
fluctuation limit, such that 98% of its total noise consisted of
phonon and photon fluctuations of the detector body. The device has
performed with a detectivity of 3.8×109cmHz/W, which is the highest reported for
any room temperature device operating in the long-wave infrared (λ∼8−12µm). The device has shown a
noise-equivalent temperature difference of 4.5 mK and a time
constant of 7.4 ms. The detector contains a subwavelength
perforated absorber with an absorption-per-unit-thermal mass-per-area
of 1.54×1022kg−1m−2, which is approximately
1.6–32.1 times greater than the state-of-the-art absorbers
reported for any infrared application. The perforated absorber
membrane is mostly open space, and the solid portion consists of Ti, SiN
x
, and Ni layers with an overall fill
factor of ∼28%, where subwavelength interference,
cavity coupling, and evanescent field absorption among units induce
the high absorption-per-unit-thermal mass-per-area. Readout of the
detector occurs via infrared-absorption-induced deformation using a
Mach–Zehnder interferometry technique (at λ=633nm), chosen for its long-term
compatibility with array reads using a single integrated
transceiver.
Sepsis awareness and knowledge amongst nurses, physicians and paramedics of a tertiary care center in Switzerland: A survey-based cross-sectional study
Authors: Regina Jean , Le Pogam Marie-Annick , Niemi Tapio , Akrour Rachid , Pepe Santino , Lehn Isabelle , Wasserfallen Jean-Blaise , Calandra Thierry , Meylan Sylvain 
Published: June 2023

Background
Sepsis is a leading cause of morbidity and mortality. Prompt recognition and management are critical to improve outcomes.

Methods
We conducted a survey among nurses and physicians of all adult departments of the Lausanne University Hospital (LUH) and paramedics transporting patients to our hospital. Measured outcomes included professionals’ demographics (age, profession, seniority, unit of activity), quantification of prior sepsis education, self-evaluation, and knowledge of sepsis epidemiology, definition, recognition, and management. Correlation between surveyed personnel and sepsis perceptions and knowledge were assessed with univariable and multivariable logistic regression models.

Results
Between January and October 2020, we contacted 1’216 of the 4’417 professionals (27.5%) of the LUH, of whom 1’116 (91.8%) completed the survey, including 619 of 2’463 (25.1%) nurses, 348 of 1’664 (20.9%) physicians and 149 of 290 (51.4%) paramedics. While 98.5% of the participants were familiar with the word “sepsis” (97.4% of nurses, 100% of physicians and 99.3% of paramedics), only 13% of them (physicians: 28.4%, nurses: 5.9%, paramedics: 6.8%) correctly identified the Sepsis-3 consensus definition. Similarly, only 48% and 49.3% of the physicians and 10.1% an 11.9% of the nurses knew that SOFA was a sepsis defining score and that the qSOFA score was a predictor of increased mortality, respectively. Furthermore, 15.8% of the physicians and 1.0% of the nurses knew the three components of the qSOFA score. For patients with suspected sepsis, 96.1%, 91.6% and 75.8% of physicians respectively chose blood cultures, broad-spectrum antibiotics and fluid resuscitation as therapeutic interventions to be initiated within 1 (76.4%) to 3 (18.2%) hours. For nurses and physicians, recent training correlated with knowledge of SOFA score (ORs [95%CI]: 3.956 [2.018–7.752] and 2.617 [1.527–4.485]) and qSOFA (ORs [95%CI]: 5.804 [2.653–9.742] and 2.291 [1.342–3.910]) scores purposes. Furthermore, recent training also correlated with adequate sepsis definition (ORs [95%CI]: 1.839 [1.026–3.295]) and the components of qSOFA (ORs [95%CI]: 2.388 [1.110–5.136]) in physicians.

Conclusions
This sepsis survey conducted among physicians, nurses and paramedics of a tertiary Swiss medical center identified a deficit of sepsis awareness and knowledge reflecting a lack of sepsis-specific continuing education requiring immediate corrective measures.
Prevalence and factors associated with undiagnosed and uncontrolled heart disease: A study based on self-reported chronic heart disease and symptom-based angina pectoris among middle-aged and older Indian adults
Authors: Ahmed Waquar , Muhammad T. , Maurya Chanda , Akhtar Saddaf Naaz 
Published: June 2023

Background
This study aimed to examine the prevalence of heart diseases and angina pectoris and associated factors among middle-aged and older Indian adults. Additionally, the study examined the prevalence and associated factors of undiagnosed and uncontrolled heart disease among middle-aged and older adults based on self-reported chronic heart disease (CHD) and symptom-based angina pectoris (AP).

Methods
We used cross-sectional data from the first wave of the Longitudinal Ageing Study of India, 2017–18. The sample consists of 59,854 individuals (27, 769 males and 32,085 females) aged 45 years and above. Maximum likelihood binary logistic regression models were employed to examine the associations between morbidities, other covariates (demographic factors, socio-economic factors and behavioral factors) and heart disease and angina.

Results
A proportion of 4.16% older males and 3.55% older females reported the diagnosis of heart diseases. A proportion of 4.69% older males and 7.02% older females had symptom-based angina. The odds of having heart disease were higher among those who were hypertensive and who had family history of heart disease, and it was higher among those whose cholesterol levels were higher. Individuals with hypertension, diabetes, high cholesterol and family history of heart disease were more likely to have angina than their healthy counterparts. The odds of undiagnosed heart disease were lower but the odds of uncontrolled heart disease were higher among those who were hypertensive than non-hypertensive individuals. Those having diabetes were less likely to have undiagnosed heart disease while among the diabetic people the odds of uncontrolled heart disease were higher. Similarly, higher odds were observed among people with high cholesterol, having stroke and also among those who had a history of heart disease than their counterparts.

Conclusions
The present study provided a comparative prevalence of heart disease and agina and their associations with chronic diseases among middle-aged and older adults in India. The higher prevalence of undiagnosed and uncontrolled heart disease and their risk factors among middle-aged and older Indians manisfest alarming public health concerns and future health demand.
Reverse Engineering, Tom Conaghan (ed.) (2022)
Authors: Vecino Aleix Tura 
Published: June 2023

Review of: Reverse Engineering, Tom Conaghan (ed.) (2022)
London: Scratch Books, 172 pp.,
ISBN 978-1-73983-010-6, p/bk, £9.99

Reverse Engineering II, Tom Conaghan (ed.) (2022)
London: Scratch Books, 175 pp.,
ISBN 978-1-73983-013-7, p/bk, £9.99

A Very Short Introduction to the Short Story, Andrew Kahn (2021)
Oxford: Oxford University Press, 176 pp.,
ISBN 978-0-19875-463-3, p/bk, £8.99
Odpadová olympiáda - třídím, nebo recykluji?
Authors: Vašutová Dagmar 
Published: June 2023

Realizace environmentální výchovy s pomocí venkovní výuky je v posledních letech velmi častá. Shoda se objevuje již v hlavní myšlence charakterizující oba pojmy: výuka o přírodě, výuka pro přírodu a výuka v přírodě (Palmer a Neil, 2003; Donaldson a Donaldson, 2013). Vzdělávání pro životní prostředí i terénní výuka se objevují ve školním kurikulu na mnoha místech, ať již v horizontálním či vertikálním směru – od předškolního až po pregraduální vzdělávání. Tématem, které v této oblasti dlouhodobě rezonuje, jsou odpady. Tyto aspekty jsou důvodem realizace odpadové olympiády, na které se podílí naši studenti ve spolupráci s ekologickým centrem Sluňákov jako organizátoři a žáci základních či nižších středních škol jako účastníci. Hlavním tématem posledních let byla recyklace odpadů. Příspěvek hodnotí znalosti účastníků olympiády o hlavních pojmech doprovázejících nakládání s odpady: „třízení odpadu“ a „recyklace“. Zaměřuje se na výskyt záměny těchto pojmů a na vliv průběhu venkovní akce na ujasnění odpadového pojmosloví.
Ethnic tourism and Folksongs: A case study among the Blang (Bulang) of Yunnan, China
Authors: D’Amico Leonardo 
Published: June 2023

Abstract
In 2008 “Blang Nationality’s Singing and Instrument Playing” (Bulangzu tanchang) was listed as China’s intangible cultural heritage protection. The creation of ethnic parks, cultural villages, and ecomuseums in Southwest China raises some questions about the ethnic minorities’ traditional cultural/musical heritage and its sustainable development: What is the impact of ethnic tourism development on local minorities and what is the role played by government cultural policy in the preservation and dissemination of Blang musical heritage? How is this ethnic group’s identity represented in staged performances for tourists and in mass media? And what is the agency of Blang culture bearers officially appointed ‘cultural heritage inheritors’ in constructing, defining, and representing their own ethnic/musical identity? This article deals with a research project conducted mainly among the Blang of Manxi village in Xishuangbanna (Sipsongpanna), Yunnan Province, Southwest China, in the Spring of 2017. The purpose of this article is to describe and analyze the current interplay of ethnic tourism, government policy, mass media and culture bearers among an ethnic group considered a “minority among the minorities” in China and the effects of this interplay on the sustainability of traditional musical heritage.