bluuebunny/crossref_metadata_2025_split huggingface dataset:
In Situ Transmission Electron Microscopy for Sodium‐Ion Batteries
Authors: Lu Jianing , Zhang Zhi , Zheng Yifan , Gao Yihua 
Published: March 2023

AbstractSodium‐ion batteries (SIBs) have attracted tremendous attentions in recent years due to the abundance and wide distribution of Na resource on the earth. However, SIBs still face the critical issues of low energy density and unsatisfactory cyclic stability at present. The enhancement of electrochemical performance of SIBs depends on comprehensive and precise understanding of the underlying sodium storage mechanism. Although extensive transmission electron microscopy (TEM) investigations have been performed to reveal the sodium storage property and mechanism of SIBs, a dedicated review on the in situ TEM investigations of SIBs has not been reported. In this review, recent progress in the in situ TEM investigations on the morphological, structural, and chemical evolutions of cathode materials, anode materials, and solid‐electrolyte interface during the sodium storage of SIBs is comprehensively summarized. The detailed relationship between structure/composition of electrode materials and electrochemical performance of SIBs has been clarified. This review aims to provide insights into the effective selection and rational design of advanced electrode materials for high‐performance SIBs.
Synthesis and Plasmonic Chiroptical Properties of Double‐Helical Gold Nanorod Enantiomers
Authors: Zhang Ning‐Ning , Shen Zhi‐Li , Gao Shu‐Yang , Peng Fei , Cao Zi‐Jun , Wang Yan , Wang Zizhun , Zhang Wei , Yang Yang , Liu Kun , Sun Tianmeng 
Published: March 2023

AbstractChiroplasmonic nanostructures have drawn increasing attention in the applications of photonics, biosensing, and asymmetric catalysis owing to their intense chiroptical activities. However, the types of plasmonic nanoparticles with the intrinsic chiral shapes are still rare now. Herein, the authors report a seed‐mediated strategy for synthesis of chiral‐morphology gold nanorods (GNRs) with a novel 222 symmetry as same as that of DNA double helixes. The chiral GNRs with their sides twisted into a double‐helical‐strip shape are synthesized by the formation of high‐Miller‐index side surfaces through the regrowth of GNRs. The chiral GNRs exhibit an excellent plasmonic circular dichroism response in the visible and near‐infrared regions, which is consistent with the finite‐difference time‐domain simulations. Moreover, by adjusting synthetic parameters, the shape and chiroptical response of 222‐symmetry chiral GNRs can be tuned. This work holds a promise for the fabrication of chiroplasmonic nanoparticles with tailored shapes toward chiroptical applications.
Protein‐basierte Nanopartikel: Von Wirkstofftransport zu Bildgebung, Nanokatalyse und Proteintherapie
Authors: Kaltbeitzel Jonas , Wich Peter R. 
Published: March 2023

AbstractProteine und Enzyme sind äußerst vielseitige Biomaterialien, die aufgrund ihrer hohen Spezifität für Rezeptoren und Substrate, ihrer Abbaubarkeit, geringen Toxizität und insgesamt guten Biokompatibilität hervorragend für ein breites Spektrum medizinischer Anwendungen geeignet sind. Durch die Anordnung mehrerer nativer oder modifizierter Proteine zu nanometergroßen Protein‐Nanopartikeln können zusätzliche vorteilhafte Eigenschaften wie eine erhöhte Stabilität im Blutstrom erreicht werden. In diesem Aufsatz konzentrieren wir uns auf künstliche Nanopartikelsysteme, bei denen Proteine das Hauptstrukturelement sind und nicht nur als eingeschlossene Wirkstoffe transportiert werden. Während unter natürlichen Bedingungen lediglich bestimmte Proteine definierte Aggregate und Nanopartikel bilden, können durch chemische Modifikationen oder Veränderungen in der physikalischen Umgebung Nanopartikel aus vielen verschiedenen globulären Proteinen und Enzymen hergestellt werden. Fortschritte bei den Herstellungsmethoden von proteinbasierten Nanopartikeln haben zu einer neuen Generation von Nanosystemen geführt, die über einfache Wirkstofftransporter hinausgehen und vielfältige Anwendungen ermöglichen, wie z.B. gezielte Arzneimittelabgabe, Theranostik, Nanokatalyse und Proteintherapie.
Struktur und Bindung im amorphen roten Phosphor**
Authors: Zhou Yuxing , Elliott Stephen R. , Deringer Volker L. 
Published: March 2023

AbstractAmorpher roter Phosphor (a‐P) stellt eine der verbleibenden Herausforderungen in der Strukturchemie der Elemente dar. In diesem Beitrag klären wir Struktur, Stabilität und chemische Bindung im a‐P auf Grundlage voraussetzungsfreier Rechnungen auf, indem wir maschinelles Lernen und dichtefunktionaltheoretische (DFT‐) Methoden kombinieren. Wir zeigen, dass die Energien von a‐P‐Strukturen leicht höher liegen als jene von Phosphor‐Nanostäben, mit denen sie eng verwandt sind, und dass die Stabilität von a‐P mit dem Grad an struktureller Relaxation und mittelreichweitiger Ordnung verknüpft ist. Wir vervollständigen damit die Stabilitätsreihe der Phosphorallotrope [Angew. Chem. Int. Ed. 2014, 53, 11629], indem wir die bislang unvollständig verstandene amorphe Phase hinzufügen, und wir quantifizieren die kovalenten und van‐der‐Waals‐Wechselwirkungen in allen wichtigen Phasen des Phosphors. Wir untersuchen darüberhinaus die elektronische Zustandsdichte, einschließlich jener des wasserstoffhaltigen a‐P. Über die vorliegende Arbeit hinaus erwarten wir, dass unsere Strukturmodelle weiterführende voraussetzungsfreie Untersuchungen ermöglichen werden – beispielsweise zu a‐P‐basierten Batteriematerialien.
Precise Synthesis of Optically Active and Thermo‐degradable Poly(trifluoromethyl methylene) with Circularly Polarized Luminescence
Authors: Xu Xun‐Hui , Kang Shu‐Ming , Gao Run‐Tan , Chen Zheng , Liu Na , Wu Zong‐Quan 
Published: March 2023

AbstractDeveloping high performance and environment‐friendly fluoropolymers is greatly desired. In this work, we found that 2‐diazo‐1,1,1‐trifluoroethane can be polymerized by air‐stable alkyne‐palladium(II) catalysts following a living polymerization mechanism, affording a fluoropolymer, poly(trifluoromethyl methylene) in high yield with controlled molar mass and low dispersity. This polymer bears trifluoromethyl on every main chain atom and thus has good resistance to chemical corrosion, high hydrophobicity, and excellent dielectric constant with low dielectric loss. Due to the steric hindrance between the trifluoromethyl pendants, the synthetic poly(trifluoromethyl methylene) can twist into a stable helix. The one‐handed preferred helices synthesized using chiral PdII‐catalysts exhibit high optical activity and circularly polarized luminescence. Remarkably, such polymer can be completely degraded to (E)‐1,1,1,4,4,4‐hexafluorobut‐2‐ene at high temperatures (>280 °C). Additionally, taking advantage of the living chain end, the polymer can be further modified.
Multiscale Dot‐Wire‐Sheet Heterostructured Nitrogen‐Doped Carbon Dots‐Ti3C2Tx/Silk Nanofibers for High‐Performance Fiber‐Shaped Supercapacitors
Authors: Zhou Zhenjie , Li Peng , Man Zengming , Zhu Xiaolin , Ye Siyuan , Lu Wangyang , Wu Guan , Chen Wenxing 
Published: March 2023

AbstractFiber‐shaped supercapacitors (FSCs) have become one of the significantly strategical flexible energy‐storage materials towards future wearable textile electronics and metaverse technologies. Here, we develop the high‐performance FSCs based on multiscale dot‐wire‐sheet heterostructure microfiber of nitrogen‐doped carbon dots‐Ti3C2Tx/silk nanofibers (NCDs‐Ti3C2Tx/SNFs) hybrids via microfluidic fabrication. Due to the enlarged interlayer spacing, plentiful porous channels, accelerated H+ ion transport dynamics, large electrical conductivity and excellent mechanical strength/flexibility, the NCDs‐Ti3C2Tx/SNFs possesses high volumetric capacitance (2218.7 F cm−3) and reversible charge–discharge stability in 1 M H2SO4 electrolyte. Furthermore, the solid‐state FSCs present high energy density (57.9 mWh cm−3), good capacitance (1157 F cm−3), long‐life cycles (82.3 % capacitance retention after 40000 cycles), which realize the actual energy‐supply applications (powering lamp, watch and toy car).
Do altmetric scores reflect article quality? Evidence from the UK Research Excellence Framework 2021
Authors: Thelwall Mike , Kousha Kayvan , Abdoli Mahshid , Stuart Emma , Makita Meiko , Wilson Paul , Levitt Jonathan 
Published: March 2023

AbstractAltmetrics are web‐based quantitative impact or attention indicators for academic articles that have been proposed to supplement citation counts. This article reports the first assessment of the extent to which mature altmetrics from Altmetric.com and Mendeley associate with individual article quality scores. It exploits expert norm‐referenced peer review scores from the UK Research Excellence Framework 2021 for 67,030+ journal articles in all fields 2014–2017/2018, split into 34 broadly field‐based Units of Assessment (UoAs). Altmetrics correlated more strongly with research quality than previously found, although less strongly than raw and field normalized Scopus citation counts. Surprisingly, field normalizing citation counts can reduce their strength as a quality indicator for articles in a single field. For most UoAs, Mendeley reader counts are the best altmetric (e.g., three Spearman correlations with quality scores above 0.5), tweet counts are also a moderate strength indicator in eight UoAs (Spearman correlations with quality scores above 0.3), ahead of news (eight correlations above 0.3, but generally weaker), blogs (five correlations above 0.3), and Facebook (three correlations above 0.3) citations, at least in the United Kingdom. In general, altmetrics are the strongest indicators of research quality in the health and physical sciences and weakest in the arts and humanities.
Rh(III)‐Catalyzed C−H Annulation of Sulfoxonium Ylides and 1,3‐Diynes: A Rapid Access to Alkynyl‐1‐Naphthol Derivatives
Authors: Kumar Sanjeev , Borkar Vaishnavi , Nunewar Saiprasad , Yadav Shashank , Kanchupalli Vinaykumar 
Published: March 2023

AbstractAn effective redox‐neutral strategy to synthesize aryl/alkynyl and alkyl/alkynyl substituted 1‐naphthol derivatives has been efficaciously developed by Rh(III)‐catalyzed [4+2]‐annulation of sulfoxonium ylides and 1,3‐diynes with excellent regio‐ and chemoselectivity. Subsequently, the same strategy was extended to furnish various unsymmetrical binaphthol motifs in one‐pot manner. Interestingly, the TMS‐derived 1,3‐diyne predominantly delivered the 3‐alkynyl‐1‐naphthol via desilylation pathway. The salient features such as traceless directing group, broad substrate scope, good functional group tolerance, and operationally simple conditions made the present protocol more valuable and appealing.
Extended dissipative output‐feedback control for discrete‐time bidirectional associative memory neural networks via delay‐partitioning approach
Authors: Adhira B. , Nagamani G. 
Published: March 2023

AbstractThis paper is concerned with the analysis of an extended dissipativity performance for a class of bidirectional associative memory (BAM) neural networks (NNs) having time‐varying delays. To achieve this, the idea of the delay‐partitioning approach is used, where the range of time‐varying delay factors is partitioned into a finite number of equidistant subintervals. A delay‐partitioning based Lyapunov–Krasovskii function is introduced on these intervals, and some new delay‐dependent extended dissipativity results are established in terms of linear matrix inequalities, which also depend on the partition size of the delay factor. Further, numerical examples are performed to acknowledge the extended dissipativity performance of delayed discrete‐time BAM NN; further, four case studies were explored with their simulations to validate the impact of the delay‐partitioning approach.
Revisiting the emission line source detection problem in integral field spectroscopic data
Authors: Herenz Edmund Christian 
Published: March 2023

AbstractWe present a 3‐dimensional matched filtering approach for the blind search of faint emission‐line sources in integral‐field spectroscopic datasets. The filter is designed to account for the spectrally rapidly varying background noise due to the telluric air glow spectrum. A software implementation of this matched filtering search is implemented in an updated version of the Line Source Detection Cataloguing tool (LSDCat2.0). Using public data from the MUSE‐Wide survey we show how the new filter design provides higher detection significances for faint emission line sources buried in between atmospheric [OH]‐bands at Å. We also show how, for a given source parameterization, the selection function of the improved algorithm can be derived analytically from the variances of the data. We verify this analytic solution against source insertion and recovery experiments in the recently released dataset of the MUSE eXtreme Deep Field (MXDF). We then illustrate how the selection function has to be rescaled for 3D emission line source profiles that are not fully congruent with the template. This procedure alleviates the construction of realistic selection functions by removing the need for computationally cumbersome source insertion and recovery experiments.
Viability of non‐edible oilseed plants and agricultural wastes as feedstock for biofuels production: a techno‐economic review from an African perspective
Authors: Kichonge Baraka , Kivevele Thomas 
Published: March 2023

AbstractGiven the benefits of biofuels over conventional fuels, there is concern that widespread production of biofuels from edible feedstocks to meet demand will lead to food insecurity and other socioeconomic challenges. Thus, the goal of this research is to look into the techno‐economic potential of non‐edible oilseed plants and agricultural wastes as primary feedstocks for biofuel production in Africa. The inability of biofuel to cope in the fuel market has been demonstrated to be due to the high production costs, which limit profitability because the end price is heavily influenced by that of conventional fuel. However, the high production costs are entirely due not only to components such as feedstock, conversion processes, and infrastructure but also to a lack of techno‐economic assessment (TEA). African biofuel production can be competitively industrialized through the adoption of strong supportive policies and programs. Adoption of these policies and programs is critical for capitalizing on the benefits of non‐edible feedstocks in biofuel production while also boosting rural development through job creation. Techno‐economic assessment of conversion processes and infrastructure is recommended to provide a clear picture of the techno‐economic aspects, serving as a blueprint for the design of biofuel production facilities. Further, TEA has been shown to be a useful tool in the development process of new technologies aimed at lowering overall production costs and making biofuel more affordable. The combination of TEA and enabling policies and programs will increase the price competitiveness of biofuels, allowing them to capture a sizable share of the fuel market. © 2023 Society of Industrial Chemistry and John Wiley & Sons Ltd.
Cross‐linked polystyrene and polydivinylbenzene release significant amounts of carbon monoxide and hydrogen at ambient temperature
Authors: Thanh Nguyen Huu , Shaariikhuu Erdenechimeg , Nguyen Thi Xuyen , Hossain Muhammad Sarwar , Tae Eunju Lee , Reddy Guda Dinneswara , Yoon Kyung Byung 
Published: March 2023

AbstractCross‐linked polystyrene and polydivinylbenzene (PDVB) have unreacted pendant vinyl groups. They readily undergo aging or oxidation with air even at room temperature, giving rise to formation of OH and  (CO)CH3 groups within the polymers. We now report that the aging process involves the release of carbon monoxide (CO) and hydrogen (H2) in significant amounts at 40 °C and the rate increases with time and temperature. The amounts of CO and H2 released from PDVB at a given temperature can be expressed using a polynomial equation of Aa = Bt + Ct2, where Aa is the accumulated amount, t is the time in the unit of day, and B and C are the coefficients. The coefficients B and D increase with increasing temperature. This result shows that the storage rooms for the above polymers and their composites should be well ventilated to prevent inhalation of CO by the workers and H2‐induced potential hazards.
Depressive symptoms, perceived social support, and anticipated HIV stigma among HIV‐negative/unknown men who have sex with men in China during the COVID‐19 pandemic: A multicenter online cross‐sectional study
Authors: Dai Zhenwei , Fu Jiaqi , Qu Yimin , Wu Yijin , Si Mingyu , Chen Xu , Wang Hao , Xiao Weijun , Huang Yiman , Yu Fei , Mi Guodong , Su Xiaoyou 
Published: March 2023

AbstractObjectiveTo investigate the prevalence of depressive symptoms among human immunodeficiency virus (HIV)‐negative/unknown men who have sex with men (MSM) in China and explore the relationship between perceived social support, anticipated HIV stigma, and depressive symptoms.MethodsParticipants in this study were recruited from a gay social networking app (Blued) in China by convenience sampling from December 16, 2020 to March 1, 2021. Perceived Social Support Questionnaire, Anticipated HIV Stigma Questionnaire, and Center for Epidemiologic Studies Depression Scale were used to measure the social support, anticipated HIV stigma, and depressive symptoms of participants. Confirmatory factor analysis was performed to assess the reliability and validity of the measurement model. Structural equation modeling was employed to evaluate the association of perceived social support, anticipated HIV stigma, and depressive symptoms, as well as the mediation effects.ResultsOverall, 47.70% (665/1394) of the participants had depressive symptoms. Perceived social support could have both direct and indirect effects on depressive symptoms with the mediating role of anticipated HIV stigma among HIV‐negative/unknown MSM.ConclusionTailored interventions regarding perceived social support and anticipated HIV stigma, such as group therapy, mutual support groups and mindfulness training, with the involvement of non‐governmental or governmental organizations, should be taken into account to reduce depressive symptoms and stigma among HIV‐negative/unknown MSM in China.
Do patients with metastatic pancreatic adenocarcinoma to the lung have improved survival?
Authors: Ebrahimi Aren , Cham Jason , Puglisi Leah , De Shadarevian Melanie , Hermel David J. , Spierling Bagsic Samantha R. , Sigal Darren 
Published: March 2023

AbstractIntroductionPancreatic ductal adenocarcinoma (PDAC) is a genetically heterogeneous disease often diagnosed with synchronous metastatic disease involving the liver. Tumors with extra‐abdominal spread that bypass the liver are thought to represent a unique molecular subgroup and those with isolated pulmonary metastatic disease are thought to have a more favorable clinical phenotype.MethodWe conducted a retrospective review of patients with pathologically confirmed PDAC treated between the years 2007 and 2020 at a Scripps Health hospital. The final study sample (N = 205) included patients with isolated pulmonary metastasis (IL), isolated liver metastasis or synchronous liver and lung metastasis (LL), or metastasis to any site other than the liver or lung (NLL). Primary endpoint was overall survival (OS). Progression‐free survival (PFS) and recurrence‐free survival (RFS) were analyzed as secondary endpoints. Each survival outcome was analyzed using Cox proportional hazards tests.ResultsNo statistically significant differences were seen between the three groups in OS, PFS, or RFS. Median OS for the IL group was 561 days, 341 days for the LL group, and 441 days for the NLL group. Median RFS was 748 days for the IL group, 574 days for the LL group, and 545 days for the NLL group. Median PFS was 307 for the IL group, 236 for the LL group, and 265 for the NLL group. When comparing only the IL and LL groups, a statistically significant difference in OS was seen favoring the IL group (HR1.59 LL vs IL [ref], CI 1.04–2.41, p = 0.031)ConclusionThough statistically significant differences in survival outcomes were not seen in our population, there was a trend toward improved survival for patients with isolated lung metastases. When comparing only the IL to LL group, statistically significant overall survival favoring the IL group was seen. These findings highlight a potential prognostic indicator of metastatic PDAC.
The molecular landscape of breast mucoepidermoid carcinoma
Authors: Venetis Konstantinos , Sajjadi Elham , Ivanova Mariia , Andaloro Silvia , Pessina Simona , Zanetti Chiara , Ranghiero Alberto , Citelli Gabriele , Rossi Chiara , Lucioni Marco , Malapelle Umberto , Pagni Fabio , Barberis Massimo , Guerini‐Rocco Elena , Viale Giuseppe , Fusco Nicola 
Published: March 2023

AbstractMucoepidermoid carcinoma (MEC) of the breast is an extremely rare salivary gland‐type tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged in solid and cystic patterns. Despite their triple‐negative phenotype, breast MECs are generally considered low‐risk malignancies but their biology is largely unexplored; therefore, guidelines for clinical management are lacking. Here, we sought to characterize the molecular landscape of breast MECs. Thirteen cases were histologically reviewed, characterized for tumor‐infiltrating lymphocytes (TILs), and were subjected to immunohistochemistry for programmed death‐ligand 1 (PD‐L1, clone 22C3), EGFR, and amphiregulin (AREG). Rearrangements in MAML2 and EWSR1 were investigated by fluorescent in situ hybridization. Targeted next‐generation sequencing of 161 genes was performed on eight cases. Most MECs had low histological grade (n = 10, 77%), with the presence of TILs (n = 9/12; 75%) and PD‐L1 combined positive score ranging from 10 to 20 (n = 4/6; 67%). All cases showed EGFR and AREG overexpression and were fusion negative. Enrichment of genetic alterations was observed in PI3K/AKT/mTOR and cell cycle regulation pathways, while only one case harbored TP53 mutations. This is the first study providing extensive molecular data on breast MECs and the largest collection of cases available to date in the literature. Breast MECs lack TP53 mutations found in high‐grade forms of triple‐negative breast cancers and MAML2 or EWSR1 rearrangements pathognomonic of salivary MECs. Triple‐negativity and PD‐L1 positivity suggest a window of opportunity for immunotherapy in these patients. The EGFR/AREG axis activation, coupled with the mutational patterns in PI3K/AKT/mTOR and cell cycle pathways warrants caution in considering MECs as low‐risk neoplasms.
Germacrane‐Type Sesquiterpene Lactones from Achillea millefolium L. and Their Anti‐Inflammatory Activity
Authors: Li Hongliang , Akber Aisa Haji , Li Jun 
Published: March 2023

AbstractSix undescribed germacrane‐type sesquiterpene lactones, millefoliumons A–F, and two known analogs were isolated from the ethyl acetate fraction of the whole plant of Achillea millefolium L. growing in Xinjiang, China. The structures of these compounds were fully elucidated by their 1D and 2D nuclear magnetic resonance (NMR), and high resolution mass (HR‐ESI‐MS) spectral data, and comparison with literatures. The absolute configurations of millefoliumons A–F were confirmed by experimental and calculated electronic circular dichroism data (ECD), and 13C‐NMR calculations and DP4+ probability analysis. All compounds displayed the approximate tendency to inhibit the nitric oxide (NO) release in lipopolysaccharide (LPS)‐induced BV2 cells.