bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainable Hydrodynamic of Artificial Neural Networks and Logistic Regression Model to Lane Change Serious Conflict at Unsignalized Intersection on Malaysia’s Federal Route
Authors: Mustakim Fajaruddin , Aziz Azlan Abdul , Ahmad Mohammad Nazir , Jamian Saifulnizan B. 
Published: March 2023

Abstract
The neural network approach is used to resolve the interdependencies between inputs and outputs in a major conflict on the Malaysian Federal Route’s unsignalized intersection (UI).Two group of dataset being use in this study, they are right turning motor vehicle (RTMs) which consist eight hundred forty five data and serious conflict lane change model, consist three hundred sixty three dataset. The aim of the study are to develop serious conflict lane change model by using artificial neuron network (ANN) and logistic regression method (LRM) and to identify the risk of right turning motor vehicle (RTMs) behaviour. The input data consists traffic behaviour, type of gap, road geometry and traffic facilities. Subsequently the output data will be lane change serious conflict, the study utilize SPSS 26 statistic software. The first section of the study covers the neural network, while the second section describes the strategy utilised to analyse the scientific work. Third part cover the simple analysis of lane change serious conflict and analysis of gap types. Last part is comparison result between logistic regression method and artificial neuron network. This study reveals that lane change due angular conflict, speed limit 50kph, Gap 3 type, second passenger car, motorcycles, motorcycle stop near passenger car, traffic light and lane width were found significance in lane change serious conflict models. The study has determine that RTMs is motorcycle as vulnerable mode of transport. Besides, this study found that the combination between both method ANN and LRM sustainable hydrodynamic and complement each other especially on explaining the outcomes result.
Long-term outcomes of high-dose carbon-ion radiotherapy for central non-small cell lung cancer: a single-centre, retrospective study.
Authors: aoki shuri , Nakajima Mio , Ishikawa Hitoshi , Yamamoto Naoyoshi , Mori Shinichiro , Wakatsuki Masaru , Okonogi Noriyuki , Murata Kazutoshi , Murakami Motohiro , Mori Yasumasa , Yamada Shigeru 
Published: March 2023

Abstract
Background
The feasibility and efficacy of radiation therapy (RT) for central non-small cell lung cancer (NSCLC) remain controversial owing to the increased risk of severe adverse events (AEs), including pneumonia, perforation of mediastinal organs (esophagus and trachea), and bleeding. Carbon-ion radiation therapy (CIRT) is an effective RT modality owing to its steep dose distribution and high biological efficacy. We retrospectively analyzed the clinical course of central NSCLC treated using CIRT.
Methods
Thirty patients who received CIRT with 68.4 Gy (RBE) in 12 fractions for pathologically proven central NSCLC between 2006 and 2018 were reviewed. The clinical stage was re-evaluated according to the UICC 8th edition, and adverse events were evaluated using CTCAE ver.5.0. The Kaplan–Meier method was used to evaluate overall survival (OS), disease-specific survival (DSS), and local control (LC).
Results
The median age was 75 years (range 55–85). All patients had concomitant chronic obstructive pulmonary disease (COPD), and 20 (67%) were regarded as inoperable. At a median follow-up of 63 months in surviving patients, 14 patients died, but no treatment-related deaths were observed. The 3-year OS, DSS, and LC rates were 72.4, 75.8, and 88.7%, respectively. Two patients experienced grade 3 pneumonitis, representing 6.7% of the cohort, but no grade ≥ 3 AEs involving the mediastinal organs occurred.
Conclusions
CIRT using our dose fractionation is feasible and effective for central NSCLC and may be a secure treatment option for patients with central NSCLC who are unmet for other curative treatments.
Levels of neutralizing antibodies against resident farm strain or vaccine strain are not indicators of protection against PRRSV-1 vertical transmission under farm conditions
Authors: Martin-Valls Gerard Eduard , LI Yanli , Clilverd Hepzibar , Soto Jordi , Cortey Martí , Mateu Enric 
Published: March 2023

Abstract

Background Vertical transmission is key for the maintenance of porcine reproductive and respiratory syndrome virus (PRRSV) infection in endemic farms. In most cases, neutralizing antibodies (NAb) more effectively neutralize the homologous strain, but some reports indicate the existence of broadly NAb (bNAb). In vaccinated farms, where all breeders have some levels of immunity, vertical transmission can still occur. The present study correlates the age of sows and the amplitude of NAb with PRRSV-1 vertical transmission (VT) through sampling two vaccinated farms. Results The proportion of VT events in the two examined farms ranged from 18.9–23.0%. Young sows (parity 1–2) were 1.7 times more likely to have VT than older sows (p < 0.05). Despite higher ELISA S/P antibody ratios in younger sows (p < 0.05), NAb against the resident farm strain were at a similar level between sows delivering infected and healthy piglets although mostly with low titres (2–3 log2). The titres of NAb against the vaccine virus were also low, and no correlations with VT were observed. When a panel of another 4 strains (1 isolated in the 1990s, and 3 contemporary strains) were used for the neutralization test, most sows were not capable of neutralizing the contemporary strains. Conclusions Titres of NAb could not be correlated with the occurrence of PRRSV VT. The amplitude of NAb present in most vaccinated sows is limited with a considerable proportion unresponsive regarding NAb production.
Fate of Cryptosporidium and Giardia through conventional and compact drinking water treatment plants
Authors: Moussa Ahmed S. , Ashour Ameen A. , Soliman Mohammad I. , Taha Hoda A. , Al-Herrawy Ahmad Z. , Gad Mahmoud 
Published: March 2023

Abstract
During the past thirty years, there has been a significant increase in the contamination of drinking water by enteric pathogenic protozoa, particularly Giardia and Cryptosporidium spp. Such microbial contamination has been responsible for disease outbreaks and increased background rates of disease in developed and developing countries worldwide. As such, controlling waterborne diseases is a critical aspect of public health policy and the primary objective of drinking water treatment plants (DWTPs). Limited studies applied real-time PCR (qPCR) and/or Immunofluorescence assay (IFA) for monitoring Giardia and Cryptosporidium spp., particularly in developing countries like Egypt. Samples of water from two conventional drinking water treatment plants and two compact units (CUs) were analyzed using both IFA and qPCR methods to detect Giardia and Cryptosporidium. The conventional DWTPs showed complete removal of Giardia and Cryptosporidium gene copies, whereas Mansheyat Alqanater and Niklah CUs achieved only partial removal. Specifically, Cryptosporidium gene copies removal rates were 33.33% and 60% for Mansheyat Alqanater and Niklah CUs, respectively. Niklah CU also removed 50% of Giardia gene copies, but no Giardia gene copies were removed by Mansheyat Alqanater CU. Conventional DWTPs were more effective than CUs in removing enteric protozoa. The contamination of drinking water by enteric pathogenic protozoa remains a significant issue globally, leading to increased disease rates. Infectious disease surveillance in drinking water is an important epidemiological tool to monitor the health of a population.
Comparative transcriptome analysis and weighted gene co-expression network analysis to identify core in Musa acuminata sub-varieties infected by Fusarium oxysporum f.sp. cubense TR4
Authors: Lakshmi PTV , Kumar Amrendra , S. AJNA. A. , Raveendran Abitha P , Chaudhary Anjali , Shanmugam Adhitthan , Arunachalam Annamalai 
Published: March 2023

Abstract
Bananas a high-nutrient fruit crop that ranks fourth in terms of gross value production after rice, wheat, and maize. Fusarium wilt of banana, caused by fungal pathogens Fusarium oxysporum f. sp. cubensetropical race 4 (Foc TR4), is considered as the most destructive disease in the world and results in extensive damage of the crop leading up to complete productivity loss. These cavendish cultivars are vulnerable to Fusarium oxysporum f. sp. cubense tropical race 4. (Foc TR4). Benzothiadiazole (BTH) is a plant resistance inducer that can enhance the defensive mechanism of plants against this pathogen. However, the mechanism behind the defensive response is still unknown. In this study, bioinformatics tools were used to publicly available transcriptome data of multiple (Baragan, Brazilian, and Williams) cultivars of cavendish banana under Fusarium oxysporum on Benzathiadiasole (BTH) of Barzillian cultivar, which was further used for comparative transcriptome analysis. The widespread use of plant resistance inducers (PRIs) such as Benzathiadiasole (BTH) is a new strategy to stimulate the defence response in banana plants to protect against pathogen infection. The differential expression genes (DEGs) analyses with time series of cultivars were done, of which approximately 56.3 % (19835) genes were found to be significantly differentially expressed. The DEGs have been compared with genes found in modules of weighted gene co-expression network followed by the analysis of relevant (trait) cultivars to identify core genes, and it was found that 1110 genes were down regulated, and 671 were upregulated genes in Berangan cultivars 4 days Foc4 fungal infected samples, whereas in Brazilian cultivars one day Foc4 infections with BTH treated, 171 genes were upregulated and 125 genes were downregulated. Further, in pathway analysis, 20 pathways were identified under significant enrichment FDR, many proteins were also involved in different pathways, including sphingolipid metabolism, peroxisome, ubiquitin-mediated proteolysis and endocytosis in the roots of banana.
Depiction of an External Classical Field Effects on a Four-Level W-Configuration Atom Embedded in a Coherent Cavity Field
Authors: Ali Salama 
Published: March 2023

Abstract
This paper examines the dynamics of a W-configuration four-level atom in a quantized cavity field and the system driven by an external classical field. By applying some canonical transformations, we derive analytical solutions to the Schrdinger equation for the corresponding Hamiltonian. The effects of the external field parameters and detuning on the relative entropy of coherence, Wigner function, and Pancharatnam phase of the system are then analyzed. It is found that the external field parameter has a significant effect on the coherence of the system, while the detuning parameters may increase the maximum bounds of the coherence. In addition, the Wigner function is utilized to quantify the quantumness and classicality of the system in phase space. It is observed that the external field has a greater effect on the classicality of the system than the detuning parameters. Furthermore, the dynamics of the Pancharatnam phase displays rapid oscillations for large detuning values, whereas the external field diminishes the number of phase jumps.
Comparing the apical micro-leakage caused by various endodontic sealers in the presence and absence of moisture Single Author
Authors: Katta Prashanth Kumar 
Published: March 2023

Abstract
Introduction:Drying of the canals before endodontic obturation is still up for debate despite the existence of hydrophilic sealers. This investigation compared the apical micro-leakage of the sealers AD Seal, RealSeal SE, EndoSeal MTA, and Tubli-Seal in both dry and moist root canals.
Materials and methods: On 90 maxillary canines that had been excised, an experimental study was conducted. The canals were prepared using rotary files. Under both dry and moist root canal conditions, root canals were filled with a single gutta percha cone using one of the four sealers (15 teeth in each group). Except for the positive control group, all root surfaces were painted with oil paint and orifices were sealed with adhesive wax. Teeth were put in methylene blue and then sliced longitudinally after ten days at 100% humidity. By using a stereomicroscope, blue color permeability was determined in micrometers. Using SPSS V.18 software, data were analyzed using the t-test, ANOVA, and Scheffe post hoc test at P 0.05.
Results: In the dry groups, the mean apical micro-leakage was considerably reduced (P 0.001). In AD Seal and ZOE, respectively, there was a minimum and maximum amount of microleakage. Between dry and damp conditions, EndoSeal MTA did not show a significant difference in apical microleakage (P > 0.05). The RealSeal SE groups had considerably more apical micro-leakage (P 0.001).
Conclusion: In dry conditions, AD Seal offered the least apical micro-leakage, whereas in moist conditions, Tubli-Seal had the maximum micro-leakage. Regardless of wetness, EndoSeal MTA provided a reliable apical closure.
Bone density of the cervical, thoracic and lumbar spine measured using Hounsfield units of computed tomography – results of 4350 vertebras
Authors: Simion George , Eckardt Niklas , Ullrich Bernhard , Senft Christian , Schwarz Falko 
Published: March 2023

Abstract
Introduction
The assessment of bone density has gained significance in recent years due to the aging population. Accurate assessment of bone density is crucial when deciding on the appropriate treatment plan for spinal stabilization surgery. The objective of this work was to determine the trabecular bone density values of the subaxial cervical, thoracic and lumbar spine using Hounsfield units.
Material and Methods
Data from 200 patients who underwent contrast-enhanced polytrauma computed tomography at a maximum care hospital over a two-year period were retrospectively analyzed. HUs were measured with an elliptical measurement field in three different locations within the vertebral body: below the upper plate, in the middle of the vertebral body, and above the base plate. The measured Hounsfield units were converted into bone density values using a validated formula.
Results
The mean age of the patient collective was 47.05 years. Mean spinal bone density values decreased from cranial to caudal (C3: 231.79 mg/cm³; L5: 155.13 mg/cm³; p < 0.001), with the highest values in the upper cervical spine. Bone density values generally decreased with age in all spinal segments. There was a clear decrease in values after age 50 years (p < 0.001).
Conclusions
In our study, bone density decreased from cranial to caudal with higher values in the cervical spine. These data from the individual spinal segments may be helpful to comprehensively evaluate the status of the spine and to design a better preoperative plan before instrumentation.
Discrete modulation instability and localized waves of the coupled semi-discrete Hirota equation
Authors: Houwe Alphonse , Abbagari Souleymanou , Akinyemi Lanre , Doka Serge Yamigno 
Published: March 2023

Abstract
In this paper, we use the numerical simulation of the discrete Hirota equation to point out the localized modes and wave patterns. The discrete modulation instability is used to demonstrate how the nonlinear term generates unstable or stable modes when a little perturbation is introduced. We have also stated that for strong enough nonlinear terms, new bands emerge. Furthermore, by applying an external periodic force, we were able to push one end of the discrete Hirota model into the forbidden frequency gap. We established the threshold amplitude expression and the driven amplitude. According to one finding, the threshold of supratransmission decreases as the nonlinear term of the discrete Hirota equation increases. For specific times of propagation, we showed the propagation of the train of waves as well as the modulated wave patterns. We demonstrated the wave train traveling through the band gap, where energy jumps from the bottom to the top and vice versa, over a significant period of time. These findings will almost certainly pave the way for new nonlinear dynamics applications.
Entropology: an information-theoretic approach to understanding archaeological data
Authors: Gheorghiade Paula , Vasiliauskaite Vaiva , Diachenko Aleksandr , Price Henry , Evans Tim , Rivers Ray 
Published: March 2023

Abstract
This paper presents new tactics for characterizing the relationship between archaeological assemblages, based on entropy and its related attributes, primarily diversity, borrowing heavily from ecology. Our starting premise is that diachronic change in our data is a likely, albeit distorted, reflection of social processes and that spatial difference in data reflects cultural separation. To explore this, we have adopted a null model for comparing assemblage profiles. The modelling is tested on i) a Late Bronze Age Cretan data set compiled by one of us (PG) and ii) a 4th millennium Western Tripolye data set that was analysed earlier. The contrast between the strongly geographically and culturally heterogeneous Bronze Age Crete and the strongly homogeneous Western Tripolye culture in the Southern Bug and Dnieper interfluve show the successes and limitations of our approach. As such, this paper is not primarily about Late Bronze Age (LBA) Crete or Western Tripolye culture per se, although the modelling contributes to our understanding of Cretan archaeology of this period. A fuller discussion of Cretan archaeology and LBA datasets will be given elsewhere. Rather, we use the paper to exemplify problems with archaeological data. Even though we have ‘lots of Cretan data’ (originally 13,000 + artefacts) we cannot consider this as ‘big data’. Due to poor statistics, they only permit non-semantic analysis, particularly important when our aggregation protocols depend on how representative our data is, and whether our assemblages are treated as censuses or samples.
Augmented Lagrangian index-3 semi-recursive formulations with projections. Direct sensitivity analysis.
Authors: Varela Álvaro López , Dopico Daniel Dopico , Fernández Alberto Luaces 
Published: March 2023

Abstract
Sensitivity analysis represents a powerful tool for the optimization of multibody system dynamics. The performance of a gradient-based optimization algorithm is strongly tied to the dynamic and the sensitivity formulations considered. Accuracy and efficiency are critical to any optimization problem, thus they are key factors in the selection of the dynamic and sensitivity analysis approaches used to compute an objective function gradient. Semi-recursive methods usually outperform global methods in terms of computational time, even though they involve sometimes demanding recursive procedures. Semi-recursive methods are well suited to be combined with different constraints enforcement schemes as the augmented Lagrangian index-3 formulation with velocity and acceleration projections (ALI3-P), taking advantage of the robustness, accurate fulfillment of constraint equations and the low computational burden. The sensitivity analysis of the semi-recursive ALI3-P formulation is studied in this document by means of the direct differentiation method. As a result, a semi-recursive ALI3-P sensitivity formulation is developed for an arbitrary reference point selection, and then two particular versions are unfolded and implemented in the general purpose multibody library MBSLIM, using as reference point the center of mass (RTdyn0) or the global origin of coordinates (RTdyn1). Besides, the detailed derivatives of the recursive terms are provided, which will be useful not only for the direct sensitivity formulation presented herein, but also for other sensitivity formulations relying on the same recursive expressions. The implementation has been tested in two numerical experiments, a five-bar benchmark problem and a buggy vehicle.
Relationship Between ABO Blood Group and Microsatellite Instability in Colorectal Cancer: A Retrospective single-center Study
Authors: Karaoglan Beliz Bahar , Akyol Cihangir , Unal Ali Ekrem , Kuzu Ayhan , Savaş Berna , Utkan Gungor 
Published: March 2023

Abstract

Background
Colorectal cancer (CRC) is the second most common cancer in both women and men. Microsatellite instabil (MSI-H) CRC is a molecular subgroup and has distinct clinical and pathologic features from non-MSI-H CRC. Studies have suggested an association between hereditary antigens in the human blood group system and the risk of developing various cancers but the relationship between blood groups and MSI-H colorectal carcinoma has not been investigated. This study aimed to investigate the relationship between microsatellite instability and ABO blood group in patients with MSI-H colorectal carcinoma.
Methods
A total of 144 patients operated for non-metastatic colorectal cancer including 72 patients with MSI-H and 72 patients with non-MSI-H colorectal cancer as the control group, were included in the study. Demographic and clinicopathological features, blood groups and microsatellite status were examined among two groups. Microsatellit instability was examined by immunhistochemistery(IHC).
Results
Among all patients, the median age was 59.65 (range 24–89) and 57.6% were male. MSI-H and non-MSI-H groups were similar in terms of age, gender distribution and comorbidities. Patients with MSI-H CRC had significantly common O-blood-group than non-MSI-H group (44.4% vs 18.1%, p:0.001). Also patients with MSI-H colorectal cancer were found to have significantly more right-sided (73.6% vs 36.1%, p < 0.001), mucinous (30.4% vs 9.7%, p: 0.003), high-grade tumors and earlier stage disease.
Conclusions
MSI-H colorectal cancers are an important subgroup in colon cancer with different molecular and clinicopathological features. This study is the first to examine blood group distribution in MSI-H colorectal cancers, and it was observed that O-blood group was more common in MSI-H colorectal cancers than in non-MSI-H patients.
Treatment-seeking behaviours of malaria patients versus non-malaria febrile patients along China-Myanmar border
Authors: Xu Jian-Wei , Deng Dao-Wei , Wei Chun , Zhou Xing-Wu , Li Jian-Xiong 
Published: March 2023

Abstract
Background
Appropriate malaria treatment-seeking behavior (MTSB) is critical to timely detect malaria for prompt treatment and prevent onward transmission of the diseases in a community. The aim of this study was to compare treatment-seeking behaviours between malaria patients and non-malaria febrile patients, and analyse factors associated with appropriate MTSB along China-Myanmar border.
Methods
This case-control study matched one malaria case patient confirmed by microscopy to two controls (non-malaria febrile patients). Factors associated with appropriate MTSB was identified by a matched logistic regression analysis (LRA).
Results
Among 223 malaria case patients and 446 controls, 129 (57.8%) of the cases sought treatment first in health facilities without laboratory test compared to 163 (36.5%) of the controls (P<0.0001). A total of 85(38.1%) of the malaria case patients sought treatment in health facilities with laboratory test within 48 hours as compared with 278 (62.3%) of the controls (P<0.0001). Multivariate LRA identified that the malaria cases with Chinese nationality were less likely to seek treatment for malaria in health facilities with laboratory testwithin 48 hours compared to malaria cases with other nationalities (adjusted odds ratio [AOR]: 0.21, 95%CI: 0.07-0.68, P=0.0097), and malaria case patients residing in urban areas were more likely to seek treatment in health facilities with laboratory test within 48 hours compared to those living in rural areas (AOR: 2.16, 95%CI: 1.06-4.39, P=0.0337).
Conclusions
Malaria treatment-seeking behaviors were inappropriate. Chinese citizenship and rural residence are two independent factors associated with inappropriate MTSB. It is continuously necessary to improve appropriate MTSB through effective campaigns of information, education and communication.