bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Learners’ Experiences in Video-conference Classrooms through theExtended Technology Acceptance Model
Authors: Edwards Bosede Iyiade , Edwards Josephine Opeyemi 
Published: May 2023

The forced switch to fully online learning during the pandemic lockdown resulted in the conversion of video-conference platforms into digital classrooms. The emergency situation at the time left no room for necessary research, training and adequate deployment process, thus forcing both learners and instructors to adopt these learning environments as the only solution to learning during those times. After the lockdown seasons were over, several educational institutions have been considering hybrid instructional modes, thereby making these platforms to persist within education. This necessitates the assessment of learners’ perception on learning in these new classrooms. This study aims to inform and inspire the design of inclusive, and sensitive future learning environments and schools where the needs of all types of learners are factored into instructional design and delivery. An analysis model based on the Technology Acceptance Model (TAM) was deployed in this study which reports on findings from an online survey of 86 respondents consisting of 48 males and 38 females all educated at post-secondary levels. Respondents ages were between 17 and 60 years with a mean age of 30.49 years. Findings show positive learners’ perceptions of video-conference in terms of most constructs, with more neutral and almost negative feedback regarding support for collaboration and instructor presence. No negative perceptions were reported regarding frustration with the technology, and no difference in perception was expressed regarding continuation of virtual learning on video-conference, or return to physical classroom. Platforms were rated by respondents based on factors considered by respondents as important for learning; the highest ratings were assigned based on features including screen sharing, host meeting control capabilities and guest control.
The Diophantine equation f(x)=g(y)$f(x)=g(y)$ for polynomials with simple rational roots
Authors: Hajdu L. , Tijdeman R. 
Published: May 2023

AbstractIn this paper we consider Diophantine equations of the form where has simple rational roots and has rational coefficients. We give strict conditions for the cases where the equation has infinitely many solutions in rationals with a bounded denominator. We give examples illustrating that the given conditions are necessary. It turns out that such equations with infinitely many solutions are strongly related to Prouhet–Tarry–Escott tuples. In the special, but important case when has only simple rational roots as well, we can give a simpler statement. Also we provide an application to equal products with terms belonging to blocks of consecutive integers of bounded length. The latter theorem is related to problems and results of Erdős and Turk, and of Erdős and Graham.
Prognostic value of echocardiographic parameters in congenital diaphragmatic hernia: a systematic review and meta-analysis
Authors: Pammi Mohan , Kelagere Yashaswini , Koh Sara , Sisson Amy , Hagan Joseph , Kailin Joshua , Fernandes Caraciolo J 
Published: May 2023

BackgroundPrognostication of mortality and decision to offer extracorporeal membrane oxygenation (ECMO) treatment in infants with congenital diaphragmatic hernia (CDH) can inform clinical management.ObjectiveTo summarise the prognostic value of echocardiography in infants with CDH.MethodsElectronic databases Ovid MEDLINE, Embase, Scopus, CINAHL, the Cochrane Library and conference proceedings up to July 2022 were searched. Studies evaluating the prognostic performance of echocardiographic parameters in newborn infants were included. Risk of bias and applicability were assessed using the Quality Assessment of Prognostic Studies tool. We used a random-effect model for meta-analysis to compute mean differences (MDs) for continuous outcomes and relative risk (RR) for binary outcomes with 95% CIs. Our primary outcome was mortality; secondary outcomes were need for ECMO, duration of ventilation, length of stay, and need for oxygen and/or inhaled nitric oxide.ResultsTwenty-six studies were included that were of acceptable methodological quality. Increased diameters of the right and left pulmonary arteries at birth (mm), MD 0.95 (95% CI 0.45 and 1.46) and MD 0.79 (95% CI 0.58 to 0.99), respectively) were associated with survival. Left ventricular (LV) dysfunction, RR 2.40, (95% CI 1.98 to 2.91), right ventricular (RV) dysfunction, RR 1.83 (95% CI 1.29 to 2.60) and severe pulmonary hypertension (PH), RR 1.69, (95% CI 1.53 to 1.86) were associated with mortality. Left and RV dysfunctions, RR 3.30 (95% CI 2.19 to 4.98) and RR 2.16 (95% CI 1.85 to 2.52), respectively, significantly predicted decision to offer ECMO treatment. Limitations are lack of consensus on what parameter is optimal and standardisation of echo assessments.ConclusionsLV and RV dysfunctions, PH and pulmonary artery diameter are useful prognostic factors among patients with CDH.
Systematic scoping review of interventions to prevent and respond to child marriage across Africa: progress, gaps and priorities
Authors: Greene Margaret E , Siddiqi Manahil , Abularrage Tara F 
Published: May 2023

ObjectivesDespite the high prevalence of child marriage in Africa, little is known about the current state of the evidence on interventions to prevent and respond to child marriage in the region. The objectives of this systematic scoping review are to describe the breadth of existing evidence on child marriage prevention and response interventions, analyze where these interventions have been implemented, and identify research gaps and priorities for moving forward.MethodsThe inclusion criteria incorporated publications that: (1) focused on Africa, (2) described interventions to address child marriage, (3) were published 2000–2021 and (4) were published as peer-reviewed articles or reports in English. We searched seven databases (PubMed, PsychINFO, Embase, Cinahl Plus, Popline, Web of Science and Cochrane Library), hand-searched the websites of 15 organisations and used Google Scholar to identify research published in 2021. Two authors independently screened titles and abstracts followed by full-text reviews and data extraction for included studies.ResultsOur analysis of the 132 intervention studies identified highlights important disparities by intervention type, sub-region, and intervention activities, focus populations and impact. The greatest number of intervention studies focused on Eastern Africa. Health and empowerment approaches were most represented, followed by education and laws and policies. Norms or livelihoods approaches were least represented.ConclusionOur review finds few high-quality impact evaluations, most of which assess cash transfer programmes. There is a need to strengthen evaluative evidence on other intervention approaches including empowerment and norms change interventions, in particular. Given the linguistic and cultural diversity of the continent, more country-specific studies and research published in languages other than English are needed, particularly in high-prevalence Middle African countries.
Effect and safety of C7 neurotomy at the intervertebral foramen in patients with chronic poststroke aphasia: a multicentre, randomised, controlled study protocol
Authors: Li Tie , Feng Juntao , Hu Ruiping , Lv Minzhi , Chang Wenshuo , Ma Xingyi , Qi Wenjun , Zhang Ying , Chen Xiuen , Ding Ling , Gu Yudong , Xu Wendong 
Published: May 2023

IntroductionAphasia affects many stroke survivors; therefore, effective treatments are urgently needed. Preliminary clinical findings have suggested an association between contralateral C7–C7 cross nerve transfer and recovery from chronic aphasia. Randomised controlled trials supporting the efficacy of C7 neurotomy (NC7) are lacking. This study will explore the efficacy of NC7 at the intervertebral foramen for improving chronic poststroke aphasia.Methods and analysisThis study protocol reports a multicentre, randomised, assessor-blinded active-controlled trial. A total of 50 patients with chronic poststroke aphasia for over 1 year and with a aphasia quotient calculated by Western Aphasia Battery Aphasia Quotient (WAB-AQ) score below 93.8 will be recruited. Participants will be randomly assigned to 1 of 2 groups (25 individuals each) to receive NC7 plus intensive speech and language therapy (iSLT), or iSLT alone programme. The primary outcome is the change in Boston Naming Test score from baseline to the first follow-up after NC7 plus 3 weeks of iSLT or iSLT alone. The secondary outcomes include the changes in the WAB-AQ, Communication Activities of Daily Living-3, International Classification of Functioning, Disability and Health (ICF) speech language function, Barthel Index, Stroke Aphasic Depression Questionnaire-hospital version and sensorimotor assessments. The study will also collect functional imaging outcomes of naming and semantic violation tasks through functional MRI and electroencephalogram to evaluate the intervention-induced neuroplasticity.Ethics and disseminationThis study was approved by the institutional review boards of Huashan Hospital, Fudan University, and all participating institutions. The study findings will be disseminated through peer-reviewed publications and conference presentations.Trial registration numberChiCTR2200057180.
Hope in the era of precision oncology: a qualitative study of informal caregivers’ experiences
Authors: Kenny Katherine , Williams Veazey Leah , Broom Alex , Peterie Michelle , Page Alexander , Prainsack Barbara , Wakefield Claire E. , Itchins Malinda , Khasraw Mustafa , Lwin Zarnie 
Published: May 2023

ObjectivesTo explore informal caregivers’ perspectives on precision medicine in cancer care.DesignSemi-structured interviews with the informal caregivers of people living with cancer and receiving targeted/immunotherapies. Interview transcripts were analysed thematically using a framework approach.SettingRecruitment was facilitated by two hospitals and five Australian cancer community groups.ParticipantsInformal caregivers (n=28; 16 men, 12 women; aged 18–80) of people living with cancer and receiving targeted/immunotherapies.ResultsThematic analysis identified three findings, centred largely on the pervasive theme of hope in relation to precision therapies including: (1) precision as a key component of caregivers’ hope; (2) hope as a collective practice between patients, caregivers, clinicians and others, which entailed work and obligation for caregivers; and (3) hope as linked to expectations of further scientific progress, even if there may be no personal, immediate benefit.ConclusionsInnovation and change in precision oncology are rapidly reconfiguring the parameters of hope for patients and caregivers, creating new and difficult relational moments and experiences in everyday life and in clinical encounters. In the context of a shifting therapeutic landscape, caregivers’ experiences illustrate the need to understand hope as collectively produced, as emotional and moral labour, and as entangled in broader cultural expectations of medical advances. Such understandings may help clinicians as they guide patients and caregivers through the complexities of diagnosis, treatment, emerging evidence and possible futures in the precision era. Developing a better understanding of informal caregivers’ experiences of caring for patients receiving precision therapies is important for improving support to patients and their caregivers.
Holistic mHealth interventions for the promotion of healthy ageing: protocol for a systematic review
Authors: Zheng Shenglin , Edney Sarah Martine , Mair Jacqueline Louise , Kowatsch Tobias , Castro Oscar , Salamanca-Sanabria Alicia , Müller‐Riemenschneider Falk 
Published: May 2023

IntroductionMaintaining physical and mental health is essential for healthy ageing. It can be supported by modifying lifestyle factors such as physical activity and diet. Poor mental health, in turn, contributes to the opposing effect. The promotion of healthy ageing may therefore benefit from holistic interventions integrating physical activity, diet and mental health. These interventions can be scaled up to the population level by using mobile technologies. However, systematic evidence regarding the characteristics and effectiveness of such holistic mHealth interventions remains limited. This paper presents a protocol for a systematic review that aims to provide an overview of the current state of the evidence for holistic mHealth interventions, including their characteristics and effects on behavioural and health outcomes in general adult populations .Methods and analysisWe will conduct a comprehensive search for randomised controlled trials and non-randomised studies of interventions published between January 2011 and April 2022 in MEDLINE, Embase, Cochrane Central Register of Controlled Trials, PsycINFO, Scopus, China National Knowledge Infrastructure and Google Scholar (first 200 records). Eligible studies will be mHealth interventions targeting general adult populations with content on physical activity, diet and mental health. We will extract information on all relevant behavioural and health outcomes, as well as those related to intervention feasibility. Screening and data extraction processes will be carried out independently by two reviewers. Cochrane risk-of-bias tools will be used to assess risk of bias. We will provide a narrative overview of the findings from eligible studies. With sufficient data, a meta-analysis will be conducted.Ethics and disseminationEthical approval is not required because this study is a systematic review based on published data. We intend to publish our findings in a peer-reviewed journal and present the study at international conferences.PROSPERO registration numberCRD42022315166.
Health and total factor productivity nexus in selected sub-Saharan African countries: quadratic and threshold modelling
Authors: Adegoke Yetunde Oluranti , Mbonigaba Josue , George Gavin 
Published: May 2023

ObjectivesThe sub-Saharan African (SSA) countries have been recording a decline in total factor productivity (TFP) growth, inadequate health funding and poor health outcomes are regarded as problems that might have impeded productivity in the region. This study therefore aligns with Grossman’s theory that better health could be instrumental to productivity growth. In this paper, we establish a predictive TFP model that accommodates the roles of health, which has been omitted in prior studies. To corroborate our findings we examine the threshold relationship between health and TFP.MethodsThe study employs the fixed and random effect model, panel two-stage least squares, static and dynamic panel threshold regression model on a balanced panel data of 25 selected SSA countries from 1995 to 2020 as the estimating technique for the linear relationship and the non-linear relationship between health and TFP.ResultsThe result of the analysis reveals a positive relationship between health expenditure and TFP, health expenditure per capita and TFP. Education and other non-health factors, like Information Communication Technology (ICT) and control of corruption equally have significant positive impact on TFP. The result further shows the existence of a threshold relationship between TFP and health at 3.5% level of public health expenditure. We also discover threshold relationship between TFP and some non-health variables like education and ICT at 2.56% and 21%, respectivelyConclusionsMore importantly, the study confirms health as a determinant of TFP and also validates the existence of a non-linear relationship between TFP and health. Overall, improvements in health and its proxies have implications for TFP growth in SSA. Therefore, the increase in public health expenditure stipulated in this study should be passed into law for optimal productivity growth rate.
Associations between Insulin Index and dietary insulin load with cardiometabolic phenotype in the AZAR cohort population in north-western Iran: a cross-sectionalstudy
Authors: Faramarzi Elnaz , Somi Mohammad Hossein , Naghibi Irvani Seyed Sina , Pourhashem Nahid , Nourizadeh Amir Mohammad 
Published: May 2023

ObjectivesHyperinsulinaemia and insulin resistance are proposed as contributors to the incidence of cardiometabolic phenotypes (CMPs) with unhealthy metabolic status. This study analysed the association between dietary insulin load (DIL) and Dietary Insulin Index (DII) with CMPs in the AZAR cohort population.DesignThis study was a cross-sectional analysis of the AZAR Cohort Study, beginning in 2014 and continuing to this date.SettingThe AZAR cohort is a part of an Iranian screening programme named the Persian cohort and involves participants living in the Shabestar region, Iran for at least 9 months.ParticipantsA total of 15 006 participants agreed to partake in the study. We excluded participants with missing data (n=15), daily energy intake lower than 800 kcal (n=7) or higher than 8000 kcal (n=17), and cancer (n=85). Finally, 14 882 individuals remained.Primary and secondary outcome measuresThe gathered information included the participants' demographic, dietary, anthropometric and physical activity data.ResultsThe frequency of DIL and DII significantly decreased from the first to fourth quartiles in metabolically unhealthy participants (p≤0.001). The mean values of DIL and DII were greater in metabolically healthy participants than in unhealthy ones (p<0.001). The results of the unadjusted model showed that the risks of unhealthy phenotypes in the fourth DIL quartile decreased by 0.21 (0.14–0.32) and 0.37 (0.33–0.43), respectively, compared with the first quartile. The same model showed the same risks for DII decreased by 0.18 (0.11–0.28) and 0.39 (0.34–0.45), respectively. The results in both genders were the same as all participants combined.ConclusionsDII and DIL were correlated with a decreased OR of unhealthy phenotypes. We suggest the reason may be either a lifestyle change in metabolically unhealthy participants or elevated insulin secretion not being as detrimental as previously thought. Further studies can confirm these speculations.
Potentially inappropriate prescribing in hospitalised children: a retrospective, cross-sectional study at a tertiary children’s hospital in China
Authors: Li Siyu , Huang Liang , Zeng Linan , Yu Dan , Jia Zhi-Jun , Cheng Guo , Wang Huiqing , Zhang Lingli 
Published: May 2023

IntroductionFor improving and optimising drug use in children, we previously developed a tool (including a series of criteria for identifying potentially inappropriate prescribing in children) by literature review and the two-round Delphi technique to prevent inappropriate medication prescriptions at the prescribing stage.ObjectiveTo assess the prevalence of potentially inappropriate prescription (PIP) among hospitalised children and explore risk factors associated with PIP.DesignA retrospective cross-sectional study.SettingA tertiary children’s hospital in China.ParticipantsHospitalised children with complete medical records who received drug treatment and discharged from 1 January to 31 December 2021.Outcome measuresWe evaluated the medication prescriptions by using a series of previously developed criteria for detecting the prevalence of PIP in hospitalised children and used logistic regression to explore the risk factors (including sex, age, number of drugs, number of comorbidities, days of hospitalisation and admission departments) for PIP in children.ResultsA total of 87 555 medication prescriptions for 16 995 hospitalised children were analysed, and 19 722 PIPs were detected. The prevalence of PIP was 22.53%, and 36.92% of the children had at least one PIP during hospitalisation. The department with the highest prevalence of PIP was the surgical department (OR 9.413; 95% CI 5.521 to 16.046), followed by the paediatric intensive care unit (PICU; OR 8.206; 95% CI 6.643 to 10.137). ‘Inhaled corticosteroids for children with respiratory infections but without chronic respiratory diseases’ was the most frequent PIP. Logistic regression results showed that PIP was more likely to occur in male patients (OR 1.128, 95% CI 1.059 to 1.202) and younger patients (<2 years old; OR 1.974; 95% CI 1.739 to 2.241), and in those with more comorbidities (≥11 types; OR 4.181; 95% CI 3.671 to 4.761), concomitant drugs (≥11 types; OR 22.250; 95% CI 14.468 to 34.223) or longer hospital stay (≥30 days; OR 8.130; 95% CI 6.727 to 9.827).ConclusionsMedications for long-term hospitalised young children with multiple comorbidities should be minimised and optimised, to avoid PIP, reduce adverse drug reactions and ensure children’s medication safety. The surgery department and PICU had a high prevalence of PIP in the studied hospital and should be the focus of supervision and management in routine prescription review.
Maternal glucose levels and future risk of developing cardiovascular disease: a systematic review and meta-analysis protocol
Authors: Zeng Na , Wen Wendy , Corsi Daniel J , Li Wenshan , Kibret Taddele , Wen Shi Wu 
Published: May 2023

IntroductionHyperglycaemia during pregnancy has been considered as one of the risk factors for cardiovascular diseases (CVDs) among women. Although the evidence regarding the association between gestational diabetes mellitus (GDM) and subsequent CVD has been synthesised, there are no systematic reviews covering the evidence of the association among the non-GDM population. This systematic review and meta-analysis, therefore, aim to fill the gap by summarising existing evidence on the association between maternal glucose levels and the risk of future CVD in pregnant women with or without a diagnosis of GDM.Methods and analysisThis systematic review protocol was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols guidelines. Comprehensive literature searches were performed in the following electronic databases: MEDLINE, EMBASE and CINAHL to identify relevant papers from inception to 31 December 2022. All observational studies (case–control studies, cohort studies and cross-sectional studies) will be included. Two reviewers will perform the abstract and full-text screening based on the eligibility criteria through Covidence. The Newcastle-Ottawa Scale will be used to assess the methodological quality of included studies. Statistical heterogeneity will be assessed by using the I2test and Cochrane’s Q test. If the included studies are found to be homogeneous, pooled estimates will be calculated and meta-analysis will be performed using Review Manager 5 (RevMan) software. Random effects will be used to determine weights for meta-analysis, if needed. Pre-specified subgroup analysis and sensitivity analysis will be performed, if needed. The study results will be presented in the sequence of main outcomes, secondary outcomes and important subgroup analysis for each type of glucose level separately.Ethics and disseminationGiven no original data will be collected, ethics approval is not applicable for this review. The results of this review will be disseminated by publication and conference presentation.PROSPERO registration numberCRD42022363037.