bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incomplete reproductive barriers and genomic differentiation impact the spread of resistance mutations between green‐ and red‐colour morphs of a cosmopolitan mite pest
Authors: Xue Wen‐Xin , Sun Jing‐Tao , Witters Johan , Vandenhole Marilou , Dermauw Wannes , Bajda Sabina A. , Simma Eba A. , Wybouw Nicky , Villacis‐Perez Ernesto , Van Leeuwen Thomas 
Published: May 2023

AbstractPesticide resistance represents a clear and trackable case of adaptive evolution with a strong societal impact. Understanding the factors associated with the evolution and spread of resistance is imperative to develop sustainable crop management strategies. The two‐spotted spider mite Tetranychus urticae, a major crop pest with worldwide distribution and a polyphagous lifestyle, has evolved resistance to most classes of pesticides. Tetranychus urticae exists as either a green‐ or a red‐coloured morph. However, the extent of genetic divergence and reproductive compatibility vary across populations of these colour morphs, complicating their taxonomic resolution at the species level. Here, we studied patterns of genetic differentiation and barriers to gene flow within and between morphs of T. urticae in order to understand the factors that influence the spread of resistance mutations across its populations. We derived multiple iso‐female lines from Tetranychus populations collected from agricultural crops. We generated genomic and morphological data, characterized their bacterial communities and performed controlled crosses. Despite morphological similarities, we found large genomic differentiation between the morphs. This pattern was reflected in the incomplete, but strong postzygotic incompatibility in crosses between colour morphs, while crosses within morphs from different geographical locations were largely compatible. In addition, our results suggest recent/on‐going gene flow between green‐coloured T. urticae and T. turkestani. By screening the sequences of 10 resistance genes, we found evidence for multiple independent origins and for single evolutionary origins of target‐site resistance mutations. Our results indicate that target‐site mutations mostly evolve independently in populations on different geographical locations, and that these mutations can spread due to incomplete barriers to gene flow within and between populations.
The decoupled evolution of the organellar genomes of Silene nutans leads to distinct roles in the speciation process
Authors: Postel Zoé , Sloan Daniel B. , Gallina Sophie , Godé Cécile , Schmitt Eric , Mangenot Sophie , Drouard Laurence , Varré Jean‐Stéphane , Touzet Pascal 
Published: May 2023

Summary
There is growing evidence that cytonuclear incompatibilities (i.e. disruption of cytonuclear coadaptation) might contribute to the speciation process. In a former study, we described the possible involvement of plastid–nuclear incompatibilities in the reproductive isolation between four lineages of Silene nutans (Caryophyllaceae). Because organellar genomes are usually cotransmitted, we assessed whether the mitochondrial genome could also be involved in the speciation process, knowing that the gynodioecious breeding system of S. nutans is expected to impact the evolutionary dynamics of this genome.
Using hybrid capture and high‐throughput DNA sequencing, we analyzed diversity patterns in the genic content of the organellar genomes in the four S. nutans lineages.
Contrary to the plastid genome, which exhibited a large number of fixed substitutions between lineages, extensive sharing of polymorphisms between lineages was found in the mitochondrial genome. In addition, numerous recombination‐like events were detected in the mitochondrial genome, loosening the linkage disequilibrium between the organellar genomes and leading to decoupled evolution.
These results suggest that gynodioecy shaped mitochondrial diversity through balancing selection, maintaining ancestral polymorphism and, thus, limiting the involvement of the mitochondrial genome in evolution of hybrid inviability between S. nutans lineages.
Impact of public exhibition on the perception of birthmarks
Authors: Zolkwer Morgan B. , Whitehouse Jodi , Sanderson Saskia C. , Kinsler Veronica A. 
Published: May 2023

AbstractBackgroundThe importance of photographs in social media, the steep rise in popularity of tattoos, and the prominence of individuals with visibly different skin in fashion are likely to be changing the landscape of self‐ and public perception of birthmarks. Study objectives were to assess the impact of a photoshoot and public exhibition on the self‐perception of individuals with extensive birthmarks, and to explore the viewing public's reactions.MethodsThirty individuals with congenital melanocytic nevi (CMN) were recruited internationally. Each had a professional photoshoot portrait with their skin exposed, resulting in a public exhibition in London entitled “How do you C Me Now?” Participants/parents completed pre‐ and post‐questionnaires relating to self‐perception and the impact of their birthmarks on behavior. Over 8000 members of the public viewed the exhibition, 464 completing an on‐site questionnaire on its effects.ResultsAll participants/parents rated the experience as positive, valuable and helpful. Scores on self‐appreciation and self‐confidence were significantly higher after the photo shoot. Members of the general public overwhelmingly reported the exhibition increased their positive feelings towards people with birthmarks. The majority of public respondents also reported that the exhibition made them feel better about their own skin and about their looks in general.ConclusionThis unique exhibition and the associated research has provided a striking new perspective on potential psychological interventions for individuals with birthmarks.
Physiology and management of the peri‐parturient sow in the context of changing production conditions
Authors: Langendijk P. L. , Soede N. M. 
Published: May 2023

AbstractGenetic selection has resulted in a considerable increase in litter size, paralleled by an increase in farrowing duration and perinatal mortality. This paper describes some of the physiological changes around farrowing, and how genetic trends and sow management interact with these. Compromised farrowing can be related to nutritional management, or to housing conditions and handling of periparturient sows. Transition diets, for example, can be formulated to support calcium homeostasis and alleviate constipation. The opportunity to express natural behaviours and minimize stress around farrowing can further optimize farrowing conditions and reduce piglet mortality. Loose farrowing systems are part of the answer to the challenges around farrowing; however, current systems do not perform consistently. In conclusion, increased farrowing duration and increased perinatal mortality may to some extent be inevitably related to trends in pig production; however, they can be improved by nutritional measures, housing conditions and farrowing management.
Reviewer Acknowledgements for Studies in Media and Communication, Vol. 11, No. 4
Authors: Johnson Patricia 
Published: May 2023

Studies in Media and Communication (SMC) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether SMC publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 11, Number 4Amie Jones, University of Georgia, USAAnita Šulentić, Edward Bernays University College, CroatiaAntonio García Gómez, University of Alcalá de Henares, SpainBernard Naledzani Rasila, University of Venda, South AfricaCaitlin McLaughlin, St. Francis Xavier University, CanadaCamelia Cmeciu, Danubius University of Galati, RomaniaCarmen Pérez-Sabater, Universitat Politècnica de València, SpainDaniel Moise, Bucharest University, RomaniaDonggyu Kim, University of Southern California, USAElena Bandres-Goldaraz, Universtiy of Zaragoza, SpainEric Mensah, University of Cape Coast, GhanaFrans Sayogie, Universitas Islam Negeri Syarif Hidayatullah Jakarta, IndonesiaFred Fang, South China Normal University, ChinaGiorgio Poletti, University of Ferrara, ItalyHerman, Universitas HKBP Nommensen Pematangsiantar, IndonesiaJarlene Rodrigues Reis, Cefet/RJ, BrazilJavier Serrano Puche, University of Navarra, SpainJianbo Hou, Xi'an International Studies University, ChinaLucia Zbihlejová, University of Presov, SlovakiaMasduki Masduki, Universitas Islam Indonesia, IndonesiaMiguel Álvarez-Peralta, University Rey Juan Carlos, SpainMohammad Zamroni, Sunan Kalijaga State Islamic University, IndonesiaNavid Darvishzadeh, Georgia State University, USANingyang Chen, Soochow University, ChinaPadilla-Castillo Graciela, Complutense University of Madrid, SpainPatrick Neil M. Santiago, Nueva Ecija University of Science and Technology, PhilippinesPeggy Peattie, University of San Diego, USARafael Angel Salazar Martínez, University of Holguin-Mayari Municipality Center, CubaRafiza Luziani Varão Ribeiro Carvalho, University of Brasilia, BrazilSarah Min, Dalton State College, USASeverin Mbog, University of Douala, CameroonSixto-García José, University of Santiago de Compostela, SpainTeresa Martín García, University of Salamanca, SpainThaïs de Mendonça Jorge, University of Brasilia, BrazilTilahun Adamu Mengistie, University of Gondar, EthiopiaVerlumun Celestine Gever, University of Nigeria, NigeriaXiao Li, Hubei Institute of Fine Arts, ChinaXin Wang, North China Institute of Science and Technology, ChinaYi Luo, Montclair State University, USAYoung Joon Lim, University of Texas Rio Grande Valley, USAYufan Sunny Qin, James Madison University, USA Patricia JohnsonEditorial AssistantOn behalf of,The Editorial Board of Studies in Media and CommunicationRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://smc.redfame.com
Room-Temperature Single-Step Production of Ultrafine-Grained Bulk Metallic Sheets From Al Powder
Authors: Pariyar Abhishek , Vu Viet Q. , Kailas Satish V. , Toth Laszlo S. 
Published: May 2023

Abstract
Obtaining fully dense products with high strength in one step at room temperature by powder metallurgy (PM) is generally not possible. However, doing so would reduce manufacturing and energy costs substantially. In this work, we have attempted to achieve this on commercially pure aluminum by utilizing the friction-assisted lateral extrusion process (FALEP), which has the capability of producing sheets from bulk or powder metal in a single step, by applying large shear strain. The texture, microstructure, and mechanical properties of the fully compacted powder sample were examined and compared to the bulk sheet’s properties obtained also by FALEP. The powder-FALEP sample showed a smaller grain size and significantly higher strength. Simulations carried out by the Taylor-type lattice curvature-based polycrystal model shed light on the texture characteristics of the obtained materials and were in good agreement with the experiments.
Determinants of non-attendance at face-to-face and telemedicine ophthalmic consultations
Authors: Wagner Siegfried K , Raja Laxmi , Cortina-Borja Mario , Huemer Josef , Struyven Robbert , Keane Pearse A , Balaskas Konstantinos , Sim Dawn A , Thomas Peter B M , Rahi Jugnoo S , Solebo Ameenat Lola , Kang Swan 
Published: May 2023

Background/aimsEvaluation of telemedicine care models has highlighted its potential for exacerbating healthcare inequalities. This study seeks to identify and characterise factors associated with non-attendance across face-to-face and telemedicine outpatient appointments.MethodsA retrospective cohort study at a tertiary-level ophthalmic institution in the UK, between 1 January 2019 and 31 October 2021. Logistic regression modelled non-attendance against sociodemographic, clinical and operational exposure variables for all new patient registrations across five delivery modes: asynchronous, synchronous telephone, synchronous audiovisual and face to face prior to the pandemic and face to face during the pandemic.ResultsA total of 85 924 patients (median age 55 years, 54.4% female) were newly registered. Non-attendance differed significantly by delivery mode: (9.0% face to face prepandemic, 10.5% face to face during the pandemic, 11.7% asynchronous and 7.8%, synchronous during pandemic). Male sex, greater levels of deprivation, a previously cancelled appointment and not self-reporting ethnicity were strongly associated with non-attendance across all delivery modes. Individuals identifying as black ethnicity had worse attendance in synchronous audiovisual clinics (adjusted OR 4.24, 95% CI 1.59 to 11.28) but not asynchronous. Those not self-reporting their ethnicity were from more deprived backgrounds, had worse broadband access and had significantly higher non-attendance across all modes (all p<0.001).ConclusionPersistent non-attendance among underserved populations attending telemedicine appointments highlights the challenge digital transformation faces for reducing healthcare inequalities. Implementation of new programmes should be accompanied by investigation into the differential health outcomes of vulnerable populations.
Endoscopic mucosal resection using cold snare versus hot snare in treatment for 10–19 mm non-pedunculated colorectal polyps: protocol of a non-inferiority randomised controlled study
Authors: Jiang Qingwei , Yan Xiaxiao , Wang Duan , Zhang Shengyu , Zhang Yuelun , Feng Yunlu , Yang Aiming , Wu Dong 
Published: May 2023

IntroductionCold polypectomy has the advantages of simple operation, less time-consuming and fewer complications. Guidelines have recommended cold snare polypectomy (CSP) to resect small polyps sized ≤5 mm and sessile polyps sized 6–9 mm. However, evidence is scarce regarding cold resection for non-pedunculated polyps sized ≥10 mm. Cold snare endoscopic mucosal resection (CS-EMR) combining CSP and submucosal injection was designed to improve the complete resection rate and reduce adverse events. We hypothesise that CS-EMR is non-inferior to conventional hot snare endoscopic mucosal resection (HS-EMR) in the resection of 10–19 mm non-pedunculated colorectal polyps.Methods and analysisThis study is a prospective, randomised, open-label, non-inferiority, single-centre trial. Outpatients scheduled to undergo a colonoscopy and present eligible polyps will be randomised to receive either CS-EMR or HS-EMR. The primary endpoint is the complete resection. Considering that HS-EMR of 10–19 mm colorectal polyps will yield a complete resection rate of at least 92% and a non-inferiority margin of −10%, a total of 232 polyps will be included (one-sided α, 2.5%; β, 20%). The analyses are intended to evaluate first non-inferiority (lower limit 95% CI greater than −10% for group difference) and then superiority (lower limit 95% CI>0%) if non-inferiority is achieved. Secondary endpoints include en-bloc resection, the occurrence of adverse events, the use of endoscopic clips, resection time and cost.Ethics and disseminationThe study has been approved by the institutional review board of the Peking Union Medical College Hospital (No. K2203). All participants in the trial will provide written informed consent. The results of this trial will be published in an open-access way.Trial registration numberNCT05545787.
Critical illness myopathy and trajectory of recovery in acute kidney injury requiring continuous renal replacement therapy: a prospective observational trial protocol
Authors: Teixeira J Pedro , Griffin Benjamin R , Pal Chaitanya Anil , González-Seguel Felipe , Jenkins Nathanial , Jones Beth M , Yoshida Yuri , George Naomi , Israel Hayley Puffer , Ghazi Lama , Neyra Javier A , Mayer Kirby P 
Published: May 2023

IntroductionAcute kidney injury requiring renal replacement therapy (AKI-RRT) is common in the intensive care unit (ICU) and is associated with significant morbidity and mortality. Continuous RRT (CRRT) non-selectively removes large amounts of amino acids from plasma, lowering serum amino acid concentrations and potentially depleting total-body amino acid stores. Therefore, the morbidity and mortality associated with AKI-RRT may be partly mediated through accelerated skeletal muscle atrophy and resulting muscle weakness. However, the impact of AKI-RRT on skeletal muscle mass and function during and following critical illness remains unknown. We hypothesise that patients with AKI-RRT have higher degrees of acute muscle loss than patients without AKI-RRT and that AKI-RRT survivors are less likely to recover muscle mass and function when compared with other ICU survivors.Methods and analysisThis protocol describes a prospective, multicentre, observational trial assessing skeletal muscle size, quality and function in ICU patients with AKI-RRT. We will perform musculoskeletal ultrasound to longitudinally evaluate rectus femoris size and quality at baseline (within 48 hours of CRRT initiation), day 3, day 7 or at ICU discharge, at hospital discharge, and 1–3 months postdischarge. Additional skeletal muscle and physical function tests will be performed at hospital discharge and postdischarge follow-up. We will analyse the effect of AKI-RRT by comparing the findings in enrolled subjects to historical controls of critically ill patients without AKI-RRT using multivariable modelling.Ethics and disseminationWe anticipate our study will reveal that AKI-RRT is associated with greater degrees of muscle loss and dysfunction along with impaired postdischarge recovery of physical function. These findings could impact the in-hospital and postdischarge treatment plan for these patients to include focused attention on muscle strength and function. We intend to disseminate findings to participants, healthcare professionals, the public and other relevant groups via conference presentation and publication without any publication restrictions.Trial registration numberNCT05287204.
Implementation of barcode medication administration (BMCA) technology on infusion pumps in the operating rooms
Authors: Hogerwaard Manon , Stolk Muriël , Dijk Liselotte van , Faasse Mariët , Kalden Nico , Hoeks Sanne Elisabeth , Bal Roland , Horst Maarten ter 
Published: May 2023

BackgroundMedication administration errors (MAEs) are a major cause of morbidity and mortality. An updated barcode medication administration (BCMA) technology on infusion pumps is implemented in the operating rooms to automate double check at a syringe exchange.ObjectiveThe aim of this mixed-methods before-and-after study is to understand the medication administrating process and assess the compliance with double check before and after implementation.MethodsReported MAEs from 2019 to October 2021 were analysed and categorised to the three moments of medication administration: (1) bolus induction, (2) infusion pump start-up and (3) changing an empty syringe. Interviews were conducted to understand the medication administration process with functional resonance analysis method (FRAM). Double check was observed in the operating rooms before and after implementation. MAEs up to December 2022 were used for a run chart.ResultsAnalysis of MAEs showed that 70.9% occurred when changing an empty syringe. 90.0% of MAEs were deemed to be preventable with the use of the new BCMA technology. The FRAM model showed the extent of variation to double check by coworker or BCMA.Observations showed that the double check for pump start-up changed from 70.2% to 78.7% postimplementation (p=0.41). The BCMA double check contribution for pump start-up increased from 15.3% to 45.8% (p=0.0013). The double check for changing an empty syringe increased from 14.3% to 85.0% (p<0.0001) postimplementation. BCMA technology was new for changing an empty syringe and was used in 63.5% of administrations. MAEs for moments 2 and 3 were significantly reduced (p=0.0075) after implementation in the operating rooms and ICU.ConclusionAn updated BCMA technology contributes to a higher double check compliance and MAE reduction, especially when changing an empty syringe. BCMA technology has the potential to decrease MAEs if adherence is high enough.
Neutrino decoherence from generalised uncertainty
Authors: Banerjee Indra Kumar , Dey Ujjal Kumar 
Published: May 2023

AbstractQuantum gravity models predict a minimal measurable length which gives rise to a modification in the uncertainty principle. One of the simplest manifestations of these generalised uncertainty principles is the linear quadratic generalised uncertainty principle which leads to a modified Heisenberg algebra. This can alter the usual von-Neumann evolution of density matrix to a Lindblad-type equation. We show how this can give rise to a decoherence in neutrino propagation in vacuum. The decoherence effects due to the linear quadratic generalised uncertainty principle are extremely minimal and is unlikely to be detectable in the existing or upcoming experimental facilities for any of the natural sources of neutrinos. We also show that, in principle, there can be other variants of generalised uncertainty principle which predicts verifiable decoherence effects for the cosmic neutrino background.
Stability of Cauchy horizon in a charged de-Sitter spacetime with dark matter
Authors: Nan Xue-Ying , Tan Jia , Jiang Jie 
Published: May 2023

AbstractThe violation of strong cosmic censorship (SCC) in RNdS black holes by a minimally coupled neutral massless scalar field has recently been discovered. This paper investigates the stability of the Cauchy horizon of a spherically charged de-Sitter black hole surrounded by dark matter under perturbations from a massless scalar field. Our results show that SCC can also be destroyed in the nearly extremal region, regardless of the presence of dark matter. However, the existence of dark matter can mitigate the extent of SCC violation, particularly when the cosmological constant and dark matter energy density are both small. Notably, the violation region of SCC as a function of the dark matter state parameter does not exhibit a simple monotonic decrease, suggesting that the influence of dark matter on SCC is not straightforward and may be complex.
Well-posedness of the Cauchy problem for the kinetic DNLS on T
Authors: Kishimoto Nobu , Tsutsumi Yoshio 
Published: May 2023

We consider the Cauchy problem for the kinetic derivative nonlinear Schrödinger equation on the torus [Formula: see text] for [Formula: see text], where the constants [Formula: see text] are such that [Formula: see text] and [Formula: see text], and [Formula: see text] denotes the Hilbert transform. This equation has dissipative nature, and the energy method is applicable to prove local well-posedness of the Cauchy problem in Sobolev spaces [Formula: see text] for [Formula: see text]. However, the gauge transform technique, which is useful for dealing with the derivative loss in the nonlinearity when [Formula: see text], cannot be directly adapted due to the presence of the Hilbert transform. In particular, there has been no result on local well-posedness in low regularity spaces or global solvability of the Cauchy problem. In this paper, we shall prove local and global well-posedness of the Cauchy problem for small initial data in [Formula: see text], [Formula: see text]. To this end, we make use of the parabolic-type smoothing effect arising from the resonant part of the nonlocal nonlinear term [Formula: see text], in addition to the usual dispersive-type smoothing effect for nonlinear Schrödinger equations with cubic nonlinearities. As by-products of the proof, we also obtain forward-in-time regularization and backward-in-time ill-posedness results.