bluuebunny/crossref_metadata_2025_split huggingface dataset:
Substrates, Cofactors, and Cellular Targets of Coagulation Factor XIa
Authors: Lira André L. , Kohs Tia C.L. , Moellmer Samantha A. , Shatzel Joseph J. , McCarty Owen J.T. , Puy Cristina 
Published: March 2023

AbstractCoagulation factor XI (FXI) has increasingly been shown to play an integral role in several physiologic and pathological processes. FXI is among several zymogens within the blood coagulation cascade that are activated by proteolytic cleavage, with FXI converting to the active serine protease form (FXIa). The evolutionary origins of FXI trace back to duplication of the gene that transcribes plasma prekallikrein, a key factor in the plasma kallikrein–kinin system, before further genetic divergence led to FXI playing a unique role in blood coagulation. While FXIa is canonically known for activating the intrinsic pathway of coagulation by catalyzing the conversion of FIX into FIXa, it is promiscuous in nature and has been shown to contribute to thrombin generation independent of FIX. In addition to its role in the intrinsic pathway of coagulation, FXI also interacts with platelets, endothelial cells, and mediates the inflammatory response through activation of FXII and cleavage of high-molecular-weight kininogen to generate bradykinin. In this manuscript, we critically review the current body of knowledge surrounding how FXI navigates the interplay of hemostasis, inflammatory processes, and the immune response and highlight future avenues for research. As FXI continues to be clinically explored as a druggable therapeutic target, understanding how this coagulation factor fits into physiological and disease mechanisms becomes increasingly important.
Novel Insights into Heterozygous Factor XIII Deficiency
Authors: Dorgalaleh Akbar 
Published: March 2023

AbstractThe prevalence and clinical significance of heterozygous factor XIII (FXIII) deficiency has long been debated, with controversial reports emerging since 1988. In the absence of large epidemiologic studies, but based on a few studies, a prevalence of 1 per 1,000 to 5,000 is estimated. In southeastern Iran, a hotspot area for the disorder, a study of more than 3,500 individuals found an incidence of 3.5%. Between 1988 and 2023, a total of 308 individuals were found with heterozygous FXIII deficiency, of which molecular, laboratory, and clinical presentations were available for 207 individuals. A total of 49 variants were found in the F13A gene, most of which were missense (61.2%), followed by nonsense (12.2%) and small deletions (12.2%), most occurring in the catalytic domain (52.1%) of the FXIII-A protein and most frequently in exon 4 (17%) of the F13A gene. This pattern is relatively similar to homozygous (severe) FXIII deficiency. In general, heterozygous FXIII deficiency is an asymptomatic condition without spontaneous bleeding tendency, but it can lead to hemorrhagic complications in hemostatic challenges such as trauma, surgery, childbirth, and pregnancy. Postoperative bleeding, postpartum hemorrhage, and miscarriage are the most common clinical manifestations, while impaired wound healing has been rarely reported. Although some of these clinical manifestations can also be observed in the general population, they are more common in heterozygous FXIII deficiency. While studies of heterozygous FXIII deficiency conducted over the past 35 years have shed light on some of the ambiguities of this condition, further studies on a large number of heterozygotes are needed to answer the major questions related to heterozygous FXIII deficiency.
In situ syringe rotation system for heavy microparticle suspension stability in electrospinning technique
Authors: Trupp Federico , Barella Matías , Cibils Roberto , Goyanes Silvia 
Published: March 2023

Electrospinning allows the fabrication of polymeric nonwovens with a wide variety of inclusions in the micro-nanofibers. However, the electrospinning of microparticle-filled polymer solutions is still limited in particle size, density, and concentration, mainly due to suspension instability during the electrospinning process, so it is not commonly investigated despite the vast number of possible applications. In this study, a simple and effective novel rotation device was developed to prevent the settling of microparticles in the polymer solution during electrospinning. The stability of polyvinyl alcohol and polyvinylidene fluoride (PVDF) solutions with indium microparticles (IMPs) of (42 ± 7) μm diameter was evaluated using LASER transmittance inside a syringe, both static and rotating for 24 h. While the static suspensions completely settled at 7 min and 9 h, respectively, depending on solution viscosity, the rotating suspensions remained stable throughout the experiment. The number and distribution of IMPs in PVDF electrospun mats were determined by optic microscopy and a novel x-ray imaging mapping method, showing 165% more IMPs in the mat obtained with the rotating syringe device. A simple analysis of the theoretical background of settling and rotating suspensions was included to understand the working mechanism of the device. Also, the electrospinning of solutions with high loadings of IMPs (up to 400% w/w PVDF) was accomplished. The simplicity and outstanding efficiency of the device shown in this work may serve as a solution to technical difficulties and as an encouragement to future research in microparticle-filled solution electrospinning.
Intercalant-induced V
t

2

g

orbital occupation in vanadium oxide cathode toward fast-charging aqueous zinc-ion batteries
Authors: Wang Yixiu , Wei Shiqiang , Qi Zheng-Hang , Chen Shuangming , Zhu Kefu , Ding Honghe , Cao Yuyang , Zhou Quan , Wang Changda , Zhang Pengjun , Guo Xin , Yang Xiya , Wu Xiaojun , Song Li 
Published: March 2023

Intercalation-type layered oxides have been widely explored as cathode materials for aqueous zinc-ion batteries (ZIBs). Although high-rate capability has been achieved based on the pillar effect of various intercalants for widening interlayer space, an in-depth understanding of atomic orbital variations induced by intercalants is still unknown. Herein, we design an NH
4
+
-intercalated vanadium oxide (NH
4
+
-V
2
O
5
) for high-rate ZIBs, together with deeply investigating the role of the intercalant in terms of atomic orbital. Besides extended layer spacing, our X-ray spectroscopies reveal that the insertion of NH
4
+
could promote electron transition to 3

d
xy

state of V
t

2

g

orbital in V
2
O
5
, which significantly accelerates the electron transfer and Zn-ion migration, further verified by DFT calculations. As results, the NH
4
+
-V
2
O
5
electrode delivers a high capacity of 430.0 mA h g
−1
at 0.1 A g
−1
, especially excellent rate capability (101.0 mA h g
−1
at 200 C), enabling fast charging within 18 s. Moreover, the reversible V
t

2

g

orbital and lattice space variation during cycling are found via ex-situ soft X-ray absorption spectrum and in-situ synchrotron radiation X-ray diffraction, respectively. This work provides an insight at orbital level in advanced cathode materials.
Human brain effects of DMT assessed via EEG-fMRI
Authors: Timmermann Christopher , Roseman Leor , Haridas Sharad , Rosas Fernando E. , Luan Lisa , Kettner Hannes , Martell Jonny , Erritzoe David , Tagliazucchi Enzo , Pallavicini Carla , Girn Manesh , Alamia Andrea , Leech Robert , Nutt David J. , Carhart-Harris Robin L. 
Published: March 2023

Psychedelics have attracted medical interest, but their effects on human brain function are incompletely understood. In a comprehensive, within-subjects, placebo-controlled design, we acquired multimodal neuroimaging [i.e., EEG-fMRI (electroencephalography-functional MRI)] data to assess the effects of intravenous (IV) N,N-Dimethyltryptamine (DMT) on brain function in 20 healthy volunteers. Simultaneous EEG-fMRI was acquired prior to, during, and after a bolus IV administration of 20 mg DMT, and, separately, placebo. At dosages consistent with the present study, DMT, a serotonin 2A receptor (5-HT2AR) agonist, induces a deeply immersive and radically altered state of consciousness. DMT is thus a useful research tool for probing the neural correlates of conscious experience. Here, fMRI results revealed robust increases in global functional connectivity (GFC), network disintegration and desegregation, and a compression of the principal cortical gradient under DMT. GFC × subjective intensity maps correlated with independent positron emission tomography (PET)-derived 5-HT2AR maps, and both overlapped with meta-analytical data implying human-specific psychological functions. Changes in major EEG-measured neurophysiological properties correlated with specific changes in various fMRI metrics, enriching our understanding of the neural basis of DMT’s effects. The present findings advance on previous work by confirming a predominant action of DMT—and likely other 5-HT2AR agonist psychedelics—on the brain’s transmodal association pole, i.e., the neurodevelopmentally and evolutionarily recent cortex that is associated with species-specific psychological advancements, and high expression of 5-HT2A receptors.
Ezafe as a linking feature within DP
Authors: Gündoğdu Songül , Erbasi Betul 
Published: March 2023

Abstract
Studies on Ezafe demonstrate that it displays considerable cross-linguistic variation, making it difficult to propose a unified analysis. Our goal is to achieve such unification by investigating the properties of Ezafe in two typologically different languages; Northern Kurdish/Kurmanji Kurdish (Iranian) and Turkish (Turkic). Taking Ezafe as a linking feature that marks dependency between the head and the non-head elements within the nominal domain, we propose that the variation can be explained with the head directionality of the language and the phase domain where the head noun lands in/remains. This allows us to account for data that were problematic for previous accounts and to extend the range of data to languages (specifically, Turkish) that have not been analyzed as Ezafe languages before.
RMO SC comparison COOMET.M.H-S3
Authors: Skliarov V , Menelao F , Borovský J , Zhamanbalin M , Obozny E , Kamkova N 
Published: March 2023

Main text
This report describes the results of comparison COOMET.M.H-S3. The comparison measurements between the five participants NSC "IM" (pilot laboratory), PTB, CMI, BelGIM, KazInSt were started in December 2014 and ended in December 2016. In the RMO SC, one set of hardness reference blocks was used consisting of 6 (six) blocks of the Superficial-Rockwell scales and hardness levels 90-94 HR15N, 40-50 HR30N, 76-84 HR30N, 43-54 HR45N, 47-53 HR30TW, 70-82 HR30TW. Agreement between the results of the participants is good.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
International comparison CCQM-K3.2019 automotive exhaust gases
Authors: Veen Adriaan M H van der , Zalewska Ewelina T , Wijk Janneke I T van , Kobayashi Midori , Akima Dai , Uehara Shinji , Fioravante Andreia L , Augusto Cristiane R , Ribeiro Claudia C , Silva Viviane , Dias Florbela , Botas Alda , Costa Carlos , Lee Joengsoon , Lee Jinbok , Lim Jeongsik , Bae Hyun-Kil , Kang Namgoo , Cecelski Christina E , Harris Kimberly J , Jr Walter R Miller , Carney Jennifer , Tshilongo James , Ntsasa Napo G , Jozela Mudalo I , Leshabane Nompumelelo , Marebane Prelly Mohweledi , Worton David R , Webber Eric B Mussell , Moreno Sergi , Brewer Paul J , Konopelko Leonid A , Kolobova Anna V , Pankratov V V , Efremova Olga V 
Published: March 2023

Main text
CCQM-K3.2019 was a repeat of the key comparison CCQM-K3 on the composition of automotive exhaust gases. New in CCQM-K3.2019 was the addition of the amount fraction oxygen to the programme. The key comparison reference values were obtained independently, using static gravimetry and appropriate corrections from purity analysis. The key comparison results show equivalence between the measurement standards maintained by the participating national metrology institutes. The demonstrated equivalence can be used to underpin services related to automotive exhaust gases as well as generically through the flexible scheme ("track A").
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Geometrical effective actions for a partially massless spin-2 field
Authors: Kan Nahomi , Aoyama Takuma , Shiraishi Kiyoshi 
Published: March 2023

Abstract
We consider nonlinear effective actions for a spin-2 field, whose ‘decoupling’ limit gives Fierz–Pauli action in D dimensional maximally symmetric spacetime. We find, especially, the effective action for a partially massless field can take a concise geometrical form. The exact solution for time evolution of the background metric in the model using the effective action is also studied.
From spin foams to area metric dynamics to gravitons
Authors: Dittrich Bianca , Kogios Athanasios 
Published: March 2023

AbstractAlthough spin foams arose as quantizations of the length metric degrees of freedom, the quantum configuration space is rather based on areas as more fundamental variables. This is also highlighted by the semi-classical limit of four-dimensional spin foam models, which is described by the Area Regge action. Despite its central importance to spin foams the dynamics encoded by the Area Regge action is only poorly understood, in particular in the continuum limit. We perform here a systematic investigation of the dynamics defined by the Area Regge action on a regular centrally subdivided hypercubical lattice. This choice of lattice avoids many problems of the non-subdivided hypercubical lattice, for which the Area Regge action is singular. The regularity of the lattice allows to extract the continuum limit and its corrections, order by order in the lattice constant. We show that, contrary to widespread expectations which arose from the so-called flatness problem of spin foams, the continuum limit of the Area Regge action does describe to leading order the same graviton dynamics as general relativity. The next-to-leading order correction to the effective action for the length metric is of second order in the lattice constant, and is given by a quadratic term in the Weyl curvature tensor. This correction can be understood to originate from an underlying dynamics of area metrics. This suggests that the continuum limit of spin foam dynamics does lead to massless gravitons, and that the leading order quantum corrections can be understood to emerge from a generalization of the configuration space from length to area metrics.
Maxwell equations with spin density
Authors: Schmidt Heinz-Jürgen , Bröcker Thomas 
Published: March 2023

Abstract
According to the Maxwell equations in its standard form the sources of the magnetic field are electric currents. But modern physics has discovered that another source of the magnetic field of, say, ferromagnets is the spin of unpaired electrons. This source can be described by a spin density
σ
(r, t) that should appear in Maxwell’s equations. One reason why this is usually avoided may be that the spin contribution can be simulated by a suitable current density j(r, t). However, this simulation is only a mathematical manipulation without a physical basis since the origin of an electron spin cannot be understood in terms of the classical picture of rotating electrons considered charged spheres. Therefore we think that it is more appropriate to directly include the spin density as a source in Maxwell’s equations.
Evaluation of characteristics of fast-response pressure-sensitive paint under low-pressure conditions
Authors: Kasai Miku , Nagata Takayuki , Uchida Kazuki , Nonomura Taku , Asai Keisuke , Egami Yasuhiro 
Published: March 2023

Abstract
In this study, fast-response polymer-ceramic pressure-sensitive paints (PC-PSP) were developed and evaluated for pressure measurement under low-pressure conditions. The PC-PSP using poly[1-trimethylsilyl)-1-propyne] (poly(TMSP)), which has high oxygen permeability under low-pressure conditions, was developed in this study. The static and dynamic characteristics of the developed poly(TMSP)-based PC-PSP were evaluated in comparison with those of conventional poly(isobutyl methacrylate) (poly(IBM)) binder and ruthenium-complex-based PC-PSPs, which have been used for pressure measurements under atmospheric pressure conditions. The particle mass content of titanium dioxide of PC-PSPs with poly(TMSP) was changed from 90 wt% to 98 wt% to increase the frequency response. The critical pigment volume concentration, so called CPVC, of the PC-PSP with poly(TMSP) and hydrophobic particles and hydrophilic particles were 95–98 wt% and 90–95 wt%, respectively. The PC-PSP using hydrophilic particles with poly(TMSP) and a particle mass content of 98 wt% could provide a cut-off frequency of approximately 4.5 kHz and a high local Stern–Volmer coefficient of 0.5 at low pressure of 2 kPa.
Structural, electronic, magnetic, and optical properties of a novel double perovskite Ba2GdRuO6
Authors: Guenez Wafa , Boudiba Sameh , Chemam Faïçal 
Published: March 2023

Abstract
The highly successful generalized gradient approximations PBE-GGA and GGA+U were employed to study in addition to the crystal structure, the electronic, magnetic, and optical properties of the double perovskite material noted Ba
2
GdRuO
6. For this purpose, the use of first principle calculation, which is considered a significant tool to investigate the properties of this kind of materials, could provide a better understanding of their possible potential applications. The stability of this new material of cubic form is validated by optimizing its structure, and tolerance factor. The electronic structure of Ba
2
GdRuO
6 shows its semiconductor behavior, which provides band gaps energy values of 1.024 eV and 1.316 eV for both GGA and GGA+U approximations, respectively. The antiferromagnetic phase originated from the strong magnetization between the Gd-4f and Ru-4d orbitals producing a magnetic moment equal to 3.99μ

B
. Furthermore, its optical properties exhibit a high optical conductivity of 105(Ω. cm)−1, an ideal band gap energy, high dielectric constants, and a strong light absorption coefficient in the visible and UV electromagnetic spectrum, making this newly designed material a promising candidate for high optoelectronic performance perovskite solar cells.
Effect of ultrathin layer of MoS2 on resonance mode coupling and hybridization of AlGaAs nanoscale Mie-resonator: a simulation study
Authors: Das Gour Mohan , Govindan V 
Published: March 2023

Abstract
light–matter interactions, specifically the interaction between Mie resonance modes originated from all-dielectric nano-resonators and exciton modes from the semiconducting transition metal di-chalcogenides (TMDCs) recently become an important field of study due to its application in nanophotonic devices and quantum information processing. Here, we performed finite element method (FEM) based numerical simulations on isolated Al
x
Ga(1-x)As (x: alloy composition) core - MoS2 ultrathin nanoshell, to study the interaction between Optical Mie resonance modes and exciton modes. The interaction between magnetic dipole (MD) modes originated from the Mie-active dielectric core and excitonic response from the thin semiconductor nano-shell takes place and appears as resonance mode coupling and hybridization in the scattering efficiency spectra. The resultant spectrum was elucidated using a semi-classical coupled mode theoretical model (CMT) and the coupling constant value was estimated, followed by the evaluation of anti-crossing spectral behavior and Rabi splitting. Furthermore, we found that all the properties of the spectrum or the resonance coupling are sensitive to the core radius, alloy composition of the core, shell thickness, and the refractive index of the surrounding medium. By systematically tailoring these parameters, one can tune the quenching dip or line width of the resonance modes. The insights from these simulations not only provided the basis for fundamental research on strong nanoscale light–matter interaction but will also be quite beneficial in fabricating high-efficiency optoelectronic and smart nanophotonic devices related to photon-exciton interactions.
Thermal efficiency of flat plate solar collector with TiO2-based nanofluid: synergistic effect of size and facet orientation
Authors: Darbandi Masih , Ziaee Zahra Valizadeh , Ahmadlouydarab Majid 
Published: March 2023

Abstract
A solar collector is an important device for collecting and converting solar energy into thermal energy. It can be synchronized to work in combination with different power sources to provide stable and continuous power. In this study, TiO2 nanoparticles (NPs) with control on the size and the exposed facet orientation were prepared through a fluorine-free solvothermal synthesis process. The as-synthesized nanoparticles were analyzed using XRD and TEM techniques. The effect of size (about 6 and 17 nm) and facet orientation ([001] and [101]) for TiO2 NPs as nanofluid on the performance of the solar collector was investigated experimentally. In the experimental solar collector setup, the highest absorption efficiency was 71.75% for TiO2 NPs with the mixed effects of size and facet orientation, whereas the absorption efficiency was 71.37% for commercially available P25 NPs. Most importantly, the combination of the size and facet orientation effect led to a positive synergy effect. The obtained results represent that the performance of the solar collector was severely affected by the size and facet orientation of the NPs.
Image encryption algorithm based on 1D-SFACF with cross-cyclic shift and adaptive diffusion
Authors: Hu Yongsheng , Nan Liyong 
Published: March 2023

Abstract
In this paper, a new one-dimensional chaotic system is proposed, which is called one-dimensional sine-fractional-adjusted-cosine-fractional (1D-SFACF). The dynamic behavior of the 1D-SFACF is analyzed by LE, bifurcation graph, trajectory, and cobweb plot. Compared to most one-dimensional chaotic systems, the 1D-SFACF has good cryptographic properties, such as larger parameter space and better chaotic behavior. Based on the excellent expressiveness of the 1D-SFACF, we design a secure image encryption algorithm using 1D-SFACF, called the image encryption algorithm based on 1D-SFACF (SFACF-IE). SFACF-IE is divided into four steps. First, the control parameters and initial values of 1D-SFACF are generated through a natural noise using a hash function. Secondly, an adaptive diffusion strategy is proposed. The starting position of the plaintext diffusion is adaptively changed according to the characteristics of the plaintext. Then, use a cross-cyclic shift to scramble. Finally, a hash function is used to generate a feedback key, the scrambled image is the input of the hash function, and the ciphertext is obtained by diffusing again. Experimental evaluations show that the algorithm is resistant to common attacks.
Emergent soliton-like solutions in the parametrically driven 1-D nonlinear Schrödinger equation
Authors: Dileep K , Murugesh S 
Published: March 2023

Abstract
We numerically investigate the long time dynamics of spatially periodic breather solutions of the 1-D nonlinear Schrödinger equation under parametric forcing of the form

f
(
x
)
=

f

0

exp
(
iKx
)

along with dissipation. In the absence of dissipation, robust soliton-like excitations are observed that travel with constant amplitude and velocity. With dissipation, these solitons lose energy (and amplitude) yet gain speed - a characteristic not observed in an ordinary soliton. Moreover, these novel solitons are found to be stable against random perturbations.