bluuebunny/crossref_metadata_2025_split huggingface dataset:
Narrative review of migraine management in patients with renal or hepatic disease
Authors: Stern Jennifer I. , Datta Shae , Chiang Chia‐Chun , Garza Ivan , Vieira Dorice L. , Robertson Carrie E. 
Published: January 2023

AbstractObjectives/BackgroundTreatment of migraine in the setting of either renal or hepatic disease can be daunting for clinicians. Not only does the method of metabolism have to be considered, but also the method of elimination/excretion of the parent drug and any active or toxic metabolites. Furthermore, it is difficult to think about liver or kidney disease in isolation, as liver disease can sometimes contribute to impaired renal function and renal disease can sometimes impair hepatic metabolism, through the cytochrome P450 system.MethodsA detailed search for terms related to liver disease, renal disease, and migraine management was performed in PubMed, Ovid Medline, Embase, and the Cochrane Library.For each medication, product labels were retrieved and reviewed using the US FDA website, with additional review of IBM Micromedex, LiverTox, and the Renal Drug Handbook.ResultsThis manuscript provides an overview of migraine drug metabolism and how it can be affected by liver and renal impairment. It reviews the standard terminology recommended by the US Food and Drug Administration for the different stages of hepatic and renal failure. The available evidence regarding the use of abortive and preventative medicines in the setting of organ failure is discussed in detail, including more recent therapies such as lasmiditan, gepants, and calcitonin gene‐related peptide antibodies.ConclusionsFor acute therapy, the use of NSAIDS should be limited, as these carry risk for both severe hepatic and renal disease. Triptans can be selectively used, often with dose guideline adjustments. Ubrogepant may be used in severe hepatic disease with dose adjustment and lasmiditan can be used in end stage renal disease. Though non‐medicine strategies may be the most reasonable initial approach, many preventative medications can be used in the setting of hepatic and renal disease, often with dose adjustment. This review provides tables of guidelines, including reduced dosing recommendations, for the use of abortive and preventative migraine medications in hepatic and renal failure.
Fabrication of high strength and thermal insulation porous ceramics via adjusting the fiberglass contents
Authors: Li Saisai , Chang Bing , Li Minghui , Ran Songlin 
Published: January 2023

AbstractFiberglass porous ceramics were successfully prepared via a foam‐gelcasting process with fiberglass and glass particles. The effects of fiber content on the rheology of foaming slurries and the structure and mechanical properties of as‐prepared porous ceramics were investigated. The results showed that as the ratio of fiberglass to glass particles increased, the thixotropy of slurries decreased, which affected the foamability of slurries. When the ratio of fiberglass to particle was 75:25, the slurries exhibited excellent flowability and outstanding foamability, which was beneficial to optimize the structure of pores and improve the properties of the porous ceramics. The porosity, compressive strength, and thermal conductivity of porous ceramics with a content of 75 wt.% fiberglass treated at 750°C were 78.3%, 2.15 MPa, and .11 W/(m·K) (room temperature), respectively. Therefore, the prepared porous ceramics with a ratio of fiberglass to particle 75:25 were regarded as an ideal candidate for thermal insulation materials.
Enhanced oxidation resistance of low‐carbon MgO–C refractories with Al3BC3–Al antioxidants: A synergistic effect
Authors: Wang Xuan , Deng Chengji , Di Jinghui , Xing Guangchao , Ding Jun , Zhu Hongxi , Yu Chao 
Published: January 2023

AbstractThe synergistic effects of Al3BC3–Al antioxidants on optimizing the oxidation resistance of low‐carbon MgO–C refractories were investigated. The results indicated that the oxidation index and rate constant of low‐carbon MgO–C refractories with optimized Al3BC3–Al additions were 13% and 1.10 × 10−4 cm2 min−1 at 1400°C for 3 h, respectively, which is much lower than that of Al or Al3BC3 containing ones. Single Al3BC3 is not a suitable antioxidant for low‐carbon MgO–C refractories; however, if Al3BC3 was initially protected and Al reacted as the antioxidant, enhanced oxidation resistance at high temperature can be achieved. The formation of dense MgO–MgAl2O4–Mg3B2O6 layer contributed to superior oxidation resistance, and the temperature for the generation of this layer was as low as 1100°C due to liquid and vapor phase–assisted reactions with Al3BC3–Al. Furthermore, a self‐repairing function was achieved at 1600°C with the combination of Al3BC3–Al additions in spite of the faster oxidation rate.
Experimental determination of the enthalpy of formation of the pyrochlore rare‐earth hafnates
Authors: Bajenova Irina A. , Guskov Anton V. , Gagarin Pavel G. , Khvan Alexandra V. , Gavrichev Konstantin S. 
Published: January 2023

AbstractIn this study, enthalpies of formation of compounds RE2Hf2O7 type (where RE = La, Pr, Nd, Sm, Eu, and Gd), with pyrochlore structure have been measured by high‐temperature oxide melt solution calorimetry. Results were compared with literature data, and dependencies of enthalpies of the formation of compounds with the pyrochlore structure from the ionic radius of rare‐earth element were analyzed. The enthalpy of formation becomes more positive with the increase in ionic radius, which is in conformity with the results earlier observed for titanates and zirconates.
Visible‐light‐driven Ni3FeN/g‐C3N4 Z‐scheme heterostructure for remarkable photocatalytic water splitting
Authors: Wang Qiaoyun , Tuerxun Nasiman , Xiao Lu , Wang Yu , Huang Caijin , Du Hong 
Published: January 2023

AbstractIt is very essential to grow efficient and abundant photocatalysts for overall water cracking to produce hydrogen. Ni3FeN nanosheets were synthesized by combining simple sol–gel and calcining methods using urea as nitrogen source. A heterostructure was constructed between Ni3FeN and g‐C3N4 to enhance the absorption capacity of visible light. The reformed Z‐scheme Ni3FeN/g‐C3N4 heterojunction exhibited an excellent visible‐light photocatalytic activity. The average hydrogen evolution rate of 5 wt% Ni3FeN/g‐C3N4 composite is 528.7 μmol h−1 g−1 due to the Z‐scheme Ni3FeN/g‐C3N4 junction, which promotes the separation of photogenerated e−/h+. Interestingly, the average H2 production of Ni3FeN/g‐C3N4 is nearly 8.3 and 3.6 times higher than that of Fe4N/g‐C3N4 and Ni4N/g‐C3N4, respectively, indicating that bimetallic nitrides as cocatalysts are more conducive to enhancing the performance of photocatalysts. Importantly, the Ni3FeN/g‐C3N4 composite exhibited good cycle stability, and the hydrogen production performance hardly changed after four cycle experiments. Furthermore, photoluminescence, electrochemical impedance spectroscopy, and transient photocurrent response show that Ni3FeN/g‐C3N4 heterojunction improves the separation efficiency of photoinduced e−/h+. This work provides a feasibility of the cocatalyst Ni3FeN for use in photocatalytic hydrogen production.
Classification Accuracy and Consistency of Compensatory Composite Test Scores
Authors: Setzer J. Carl , Cheng Ying , Liu Cheng 
Published: January 2023

AbstractTest scores are often used to make decisions about examinees, such as in licensure and certification testing, as well as in many educational contexts. In some cases, these decisions are based upon compensatory scores, such as those from multiple sections or components of an exam. Classification accuracy and classification consistency are two psychometric characteristics of test scores that are often reported when decisions are based on those scores, and several techniques currently exist for estimating both accuracy and consistency. However, research on classification accuracy and consistency on compensatory test scores is scarce. This study demonstrates two techniques that can be used to estimate classification accuracy and consistency when test scores are used in a compensatory manner. First, a simulation study demonstrates that both methods provide very similar results under the studied conditions. Second, we demonstrate how the two methods could be used with a high‐stakes licensure exam.
Trials and tribulations of transparency related to inconsistencies between plan and conduct in peer‐reviewed physiotherapy publications: A methodology review
Authors: McClenahan Brian J. , Lojacono Margaux , Young Jodi L. , Schenk Ronald J. , Rhon Daniel I. 
Published: January 2023

AbstractRationaleThe physiotherapy profession strives to be a leader in providing quality care and strongly recognizes the value of research to guide clinical practice. Adherence to guidelines for research reporting and conduct is a significant step towards high‐quality, transparent and reproducible research.Aim/ObjectiveAssess integrity between planned and conducted methodology in randomized controlled trials (RCTs) and systematic reviews (SRs) published in physiotherapy journals.MethodsEighteen journals were manually searched for RCTs and SRs published from 1 July 2021 through 31 December 2021. Studies were included if the journal or specific study was indexed in PubMed and published/translated in English. Descriptive statistics determined congruence between preregistration data and publication.ResultsForty RCTs and 68 SRs were assessed. Forty‐three SRs included meta‐analysis (MA). Of the 34 registered RCTs, 7 (20.6%) had no discrepancy between the registration and publication. Two trials (5.9%) addressed all discrepancies, 4 (11.8%) addressed some and 21 (61.8%) did not address any discrepancies. Of the 36 registered MAs, 33 (91.7%) had discrepancies between the registration and publication. Two (5.6%) addressed all discrepancies and three (8.3%) had no discrepancies. Eight SRs without MA published information not matching their registration, and none provided justification for the discrepancies.ConclusionMost RCTs/SRs were registered; the majority had discrepancies between preregistration and publication, potentially influencing the outcomes and interpretations of findings. Journals should require preregistration and compare the submission with the registration information when assessing publication suitability. Readers should be aware of these inconsistencies and their implications when interpreting and translating results into practice.
Investigating the interactive effects of temperature, pH, and salinity on Naegleria fowleri persistence
Authors: Stahl Leigha M. , Olson Julie B. 
Published: January 2023

AbstractNaegleria fowleri causes primary amoebic meningoencephalitis, a deadly infection that occurs when free‐living amoebae enter the nose via freshwater and travel to the brain. N. fowleri naturally thrives in freshwater and soil and is thought to be associated with elevated water temperatures. While environmental and laboratory studies have sought to identify what environmental factors influence its presence, many questions remain. This study investigated the interactive effects of temperature, pH, and salinity on N. fowleri in deionized and environmental waters. Three temperatures (15, 25, 35°C), pH values (6.5, 7.5, 8.5), and salinity concentrations (0.5%, 1.5%, 2.5% NaCl) were used to evaluate the growth of N. fowleri via ATP luminescent assays. Results indicated N. fowleri grew best at 25°C, and multiple interactive effects occurred between abiotic factors. Interactions varied slightly by water type but were largely driven by temperature and salinity. Lower temperature increased N. fowleri persistence at higher salinity levels, while low salinity (0.5% NaCl) supported N. fowleri growth at all temperatures. This research provided an experimental approach to assess interactive effects influencing the persistence of N. fowleri. As climate change impacts water temperatures and conditions, understanding the microbial ecology of N. fowleri will be needed minimize pathogen exposure.
Ultrasound‐assisted hot air drying characteristics of Phyllanthus emblica
Authors: Huang Wenyang , Huang Dan , Qin Yiting , Zhang Yixiao , Lu Yijun , Huang Shuai , Gong Guiliang 
Published: February 2023

AbstractThe ultrasound‐assisted hot air drying characteristics of Phyllanthus emblica was investigated in this paper. The effects of hot air temperature (60°C, 65°C, 70°C, and 75°C), ultrasonic pretreatment time (2, 4, 6, and 8 min), and ultrasonic power (200, 250, 300, and 350 W) on the drying rate, energy consumption, color change, and rehydration rate were evaluated and compared. It was found that the drying rate of Phyllanthus emblica increased with the hot air temperature. The drying time of Phyllanthus emblica with ultrasonic pretreatment was reduced by 10.0%, 25.0%, 21.4%, and 9.0% at 60°C, 65°C, 70°C, and 75°C, respectively. However, the hot air drying was not proportionally promoted by the increase of ultrasonic power or the extension of pretreatment time. Only an appropriate ultrasonic power or pretreatment time can not only improve the drying rate and rehydration rate, but also reduce the energy consumption and the total color change of the dried samples. A new drying model that considered the influences of hot air temperature, pretreatment time, and ultrasonic power was developed to fit the drying process. The results showed that the new model can accurately predict the hot air drying process of Phyllanthus emblica with and without ultrasonic pretreatment.Practical applicationsPhyllanthus emblica contains a variety of nutrients and has various biological activities. However, the harvest period and shelf life of Phyllanthus emblica is very short, and the fruit is prone to mildrew and browning after picking, which in turn leads to the loss of its nutritional and economical value. Thus, for the long‐term preservation of Phyllanthus emblica, drying techniques are needed. In the food industry, hot air drying is widely used due to its low cost and easy operation; however, it also has some disadvantages such as long drying time, the oxygen‐rich drying environment. These shortcomings lead to a low quality of dried materials. Ultrasonic pretreatment before hot air drying can improve drying efficiency without adversely affecting the drying quality of the material. In recent years, ultrasonic pretreatment before food drying has become a research hotspot.
Carbon and water conservation value of independent, place‐based repair in Lima, Peru
Authors: Lepawsky Josh , Cáceres Kathia , Gusukuma Marco , Kahhat Ramzy 
Published: January 2023

AbstractTo what extent do repair and maintenance of consumer electronics conserve the materials and energy they embody? In this paper we examine the conservation value of a cluster of independent third‐party electronics repair businesses in Lima, Peru. Drawing on a combination of methods that include fieldwork, digital methods for online sociology, and life cycle assessment (LCA) of phones and tablets we quantify the conservation value of typical repairs performed at businesses in this cluster in terms of CO2 equivalent (CO2e) and water consumption relative to new manufactures of the same categories of electronics. We model typical repair scenarios and find that repair can offer substantial conservation benefits. However, these benefits vary by device sub‐unit repaired (e.g., replacing a camera vs. replacing a display). For example, while two screen repairs through replacement is nearly equivalent to replacement with a whole new device, repairing with components that are already in the market could save around 10% of total emissions in global warming potential (GWP) for both devices. Further, we discuss the politics of attributing the conservation value achieved by the third‐party repair cluster in Lima to either domestic (that is, Peruvian) or foreign CO2e and water consumption. Whose conservation of CO2e and water is this? How do the answers to that question shape understandings of the relevance of location for industrial ecology? Our work contributes to the emerging subfield of political industrial ecology and its incorporation of spatially explicit LCAs.
Analysis of parameters about useful life extension in 70 tools and methods related to eco‐design and circular economy
Authors: Royo Marta , Chulvi Vicente , Mulet Elena , Ruiz‐Pastor Laura 
Published: January 2023

AbstractOne of the approaches followed by the circular economy (CE) to achieve sustainability through design is product life extension. Extending the life of products to make them useful for as long as possible is a means to reduce waste production and materials consumption, as well as the related impacts. For designers, conceptualizing products in a way that allows them to be used for longer is a challenge, and assessing how well they extend their lifespan can be helpful when it comes to choosing the best proposal. In this paper, 70 tools and methods related to eco‐design and circular economy are studied to determine how many of them consider parameters related to life extension and which can be applied in the early stages of design. The results of the analysis show that most of the existing tools and methods are applicable to developed products, and only a few of them take into account parameters related to extending the useful life. Of the 70 tools and methods, only 14 include some parameter related to life extension and are applicable to concepts. CE toolkit, Eco‐design PILOT, CE Designer, Circularity Assessment tool, Circularity Potential Indicator and Circular Design Tools take into consideration eight or more parameters to assess life extension in concepts. This will help designers select the most appropriate and will indicate the need for more complete tools to consider useful life extension in the early stages of design and thus enhance the selection of more sustainable products.
Ontogenetic variability of the intertympanic sinus distinguishes lineages within Crocodylia
Authors: Perrichon Gwendal , Hautier Lionel , Pochat‐Cottilloux Yohan , Raselli Irena , Salaviale Céline , Dailh Benjamin , Rinder Nicolas , Fernandez Vincent , Adrien Jérôme , Lachambre Joël , Martin Jeremy E. 
Published: January 2023

AbstractThe phylogenetic relationships within crown Crocodylia remain contentious due to conflicts between molecular and morphological hypotheses. However, morphology‐based datasets are mostly constructed on external characters, overlooking internal structures. Here, we use 3D geometric morphometrics to study the shape of the intertympanic sinus system in crown crocodylians during ontogeny, in order to assess its significance in a taxonomic context. Intertympanic sinus shape was found to be highly correlated with size and modulated by cranial shape during development. Still, adult sinus morphology distinguishes specimens at the family, genus and species level. We observe a clear distinction between Alligatoridae and Longirostres, a separation of different Crocodylus species and the subfossil Malagasy genus Voay, and a distinction between the Tomistoma and Gavialis lineages. Our approach is independent of molecular methods but concurs with the molecular topologies. Therefore, sinus characters could add significantly to morphological datasets, offering an alternative viewpoint to resolve problems in crocodylian relationships.
The utility of F‐18 FDG PET/CT for diagnosis and response evaluation of hepatosplenic tuberculosis
Authors: Kim Dae‐Weung , Park Soon‐Ah , Kim Myoung Hyoun 
Published: February 2023

AbstractA 77‐year‐old woman underwent F‐18 FDG PET/CT for evaluation of fever focus. Diffuse and intense hepatosplenic uptake was noted and lymphoma or tuberculosis was proposed. Liver biopsy revealed chronic granulomatous inflammation with Langerhans‐type giant cells and necrosis. A follow‐up PET/CT after anti‐tuberculosis treatment revealed that the hepatosplenic uptake had resolved.
Infrastructure deterioration modeling with an inhomogeneous continuous time Markov chain: A latent state approach with analytic transition probabilities
Authors: Mizutani Daijiro , Yuan Xian‐Xun 
Published: January 2023

AbstractMarkov chains have been widely used to characterize performance deterioration of infrastructure assets, to model maintenance effectiveness, and to find the optimal intervention strategies. For long‐lived assets such as bridges, the time‐homogeneity assumptions of Markov chains should be carefully checked. For this purpose, this research proposes a regime‐switching continuous‐time Markov chain of which the state transition probabilities depend on another, latent, Markov chain that characterizes the overall aging regime of an asset. With the aid of a state‐augmentation technique, closed‐form solutions for the transition probabilities are analytically derived, making the statistical analysis simple. A case study is presented using the open Ontario Bridge Condition data for provincial highway bridges. The case study demonstrates that the proposed method allows to (1) estimate a statistically superior model to the homogeneous Markov chain and (2) obtain results with comparable accuracy in approximately 48% of the computation time of the state‐of‐the‐art inhomogeneous Markov chain.
Facilitating family‐focused Care of Older adults living in Long‐Term Care in Canada during Restricted Visiting due to COVID‐19
Authors: Perry Beth , Thirsk Lorraine , Gordon Brogan 
Published: January 2023

AbstractBackgroundThe focus of this paper is exemplary gerontological nursing interventions that effectively supported families and long‐term care residents in Canada during visiting restrictions resulting from COVID‐19.ObjectiveThe aim was to describe exemplary gerontological nursing interventions that families and long‐term care residents in Canada found supportive during visiting restrictions resulting from COVID‐19.MethodsAn analysis of data artefacts including news reports, blogs and social media postings was completed.ResultsThematic analysis resulted in four themes: dedication amidst challenge, innovation and continuous learning, living their nursing values and purposeful knowledge sharing. These themes are described using a framework that depicts four pillars of exemplary nursing practice: professionalism, scholarly practice, leadership and stewardship (Riley, Beal, & Ponte, 2021).Conclusions/Implications for PracticeA link is made between these pillars of exemplary practice and enactment of family‐focused care. Recommendations focused on gerontological nursing approaches that facilitate family‐focused care for older adults residing in long‐term care are included.
Ichthyosis, cataracts, and motor delay in an infant: A case of Chanarin–Dorfman syndrome
Authors: Luu Yen , Pithadia Deeti J. , Teng Joyce , Khuu Phuong 
Published: January 2023

AbstractChanarin–Dorfman syndrome (CDS) is a rare, autosomal recessive disorder of impaired triacylglycerol catabolism leading to cytoplasmic deposition of triglycerides in various cell types. We describe the case of an 8‐month‐old boy with cataracts, strabismus, motor delays, and an ichthyosiform rash since birth. Genetic testing revealed a pathogenic variant of the ABHD5 gene, suggestive of CDS, and further workup demonstrated hepatic steatosis and myopathy. His ichthyosis improved with initiation of a diet low in very long‐chain fatty acids and medium‐chain fatty acid supplementation.