bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Quality and Management of Penicillin Allergy Labels in Pediatric Primary Care
Authors: Taylor Margaret G. , Joerger Torsten , Anvari Sara , Li Yun , Gerber Jeffrey S. , Palazzi Debra L. 
Published: February 2023

BACKGROUND AND OBJECTIVES
Penicillin allergy labels are the most common drug allergy label. The objective of this study was to describe the quality and management of penicillin allergy labels in the pediatric primary care setting.

METHODS
Retrospective chart review of 500 of 18 015 children with penicillin allergy labels born from January 1, 2010 to June 30, 2020 randomly selected from an outpatient birth cohort from Texas Children’s Pediatrics and Children’s Hospital of Philadelphia networks. Penicillin allergy risk classification (“not allergy,” “low risk,” “moderate or high risk,” “severe risk,” “unable to classify”) was determined based on documentation within (1) the allergy tab and (2) electronic healthcare notes. Outcomes of allergy referrals and penicillin re-exposure were noted.

RESULTS
Half of penicillin allergy labels were “unable to classify” based on allergy tab documentation. Risk classification agreement between allergy tabs and healthcare notes was fair (Cohen’s ĸ = 0.35 ± 0.02). Primary care physicians referred 84 of 500 (16.8%) children to an allergist, but only 54 (10.8%) were seen in allergy clinic. All children who were challenged (25 of 25) passed skin testing. Removal of allergy labels was uncommon (69 of 500, 13.8%) but occurred more often following allergy appointments (26 of 54, 48%) than not (43 of 446, 9.6%, P &lt; .001). Children delabeled by primary care physicians were as likely to tolerate subsequent penicillin-class antibiotics as those delabeled by an allergist (94% vs 93%, P = .87).

CONCLUSIONS
Penicillin allergy documentation within the allergy tab was uninformative, and children were infrequently referred to allergists. Future quality improvement studies should improve penicillin allergy documentation and expand access to allergy services.
Análise de comportamento em redes sociais
Authors: Bessa Ana Cláudia 
Published: February 2023

O monitoramento do uso das redes sociais é um procedimento que se torna mais aprimorado com o passar do tempo. Os estudos sociais também fazem uso dos dados coletados para buscar novas formas de apreender e compreender sentidos e ações na sociedade contemporânea. Este artigo aborda um trabalho de pesquisa sociológica para análises de comportamento em redes sociais desenvolvido em aulas sobre estudos de mídia. Este trabalho relata o monitoramento do uso das redes sociais pelos(as) trabalhadores(as) por aplicativo da empresa Uber através do uso da hashtag2 #Uber_brasil no Twitter. O resultado das análises revelou práticas funcionais no uso das redes e o apontamento de temas de interesse que podem ser úteis para delinear algumas percepções sobre o perfi l desta população. Somado a isso, foi possível identifi car narrativas e sentidos atribuídos aos discursos coletivos que podem auxiliar na abordagem junto a estes(as) trabalhadores(as) em pesquisas posteriores.
Metabolic Transformations in the Area of Municipal Solid Waste Management in Russian Megalopolises: The City of Moscow Case
Authors: Ermolaeva Polina O. , Ermolaeva Yulia V. , Efremenko Dmitry V. 
Published: February 2023

Based on secondary data analysis and semi-structured expert interviews (n = 90), the study analyses metabolic transformations in the area of municipal solid waste (MSW) management in Russian megalopolises using the city of Moscow as a case study. The findings suggest that the key node that triggered numerous interdependent processes involved the changes introduced in the legislation on MSW management and the decision to shut down several large MSW landfills without the simultaneous implementation of other landfills. These actions affected the health of the population and contributed to environmental inequality. The authors provide recommendations for the mitigation of risks associated with MSW generation, recycling, and storage in large Russian cities.
The Importance of Green Practices to Reduce Consumption
Authors: Zakharova Olga V. , Glazkova Anna V. , Pupysheva Irina N. , Kuznetsova Natalia V. 
Published: February 2023

In modern societies, growing consumption rates lead to the depletion of the planet’s resources and the waste generation. This paper studies green practices aimed at reducing consumption, which were published in social media communities covering separate waste collection. First, we selected nine green practices regarding separate waste collection and classified them as adaptive and transformative. Adaptive practices enhance the adaptability of a society to the deteriorating environment without implying consumption reduction. Transformative practices involve reducing substance and energy consumption due to changes in collective and individual actions. Next, we collected 1987 textual posts of six communities of Tyumen region, Russia, published in social media platform VK, and found all mentions of the nine practices using content and hermeneutic analyses. Finally, we identified transformative practices, such as the practices of exchanging, refusing from purchases, sharing, repairing, and promoting sustainable consumption. The obtained results might help some decision-makers create conditions to disseminate the described practices and to introduce new social practices targeting reducing consumption. We show the possibilities of grassroots initiatives in the greening of society.
Review on: Recent advances in mouth dissolving film
Authors: Avhad Pawan S. , Nikam Saurabh D. , Chaudhari Amit A. , Wagh Shital V. , Rayjade Meghana S. , Gosavi Prajwal Y. 
Published: February 2023

The fast dissolving orally disintegrating film are the designed to dissolve upon contact with wet surface or fluids like saliva, within a few seconds. Like a tablet, capsule, oral liquids there is no need of additional liquids like water. This is the most convenient dosage form for patients and also provides marketing advantages. In pediatric, geriatric and patient who have fear of choking orally disintegrating film is most convenient and popular dosage form. As the drug I directly absorb in blood through mucus membrane in mouth the degradation of drug in GIT and the first pass metabolism of drug is avoided which increase the arability of drug in plasma which increases therapeutic effect.This review gives information about all aspects from today’s point of view and gives idea about evaluation, formulation, manufacturing process of fast dissolving orally disintegrating film.
The role of the MOG and MTG in speech recovery of patients with hearing loss: a case study
Authors: Lee Yujun , Chen Maoqing , Yan Zhiqiang , Zhang Wenjia , Zhang Yanlong , Wang Yang , Yan Hao 
Published: February 2023

Abstract

Previous studies show that infants perceive speech left-hemisphere dominantly like adults, but the development of the language brain network in infants is given less attention. Here we show that functional connectivity (FC) with the whole brain in the middle temporal gyrus (MTG) and the middle occipital gyrus(MOG) plays different roles in language development. Two experiments were performed in the present study. In Experiment 1, activation likelihood estimation (ALE) meta-analysis was employed to identify which brain areas are correlated with the speech outcomes of CI users.Based on the convergent findings, a case study (Experiment 2) was performed with foot reflexological stimulation. Using rs-fMRI, the change of MTG and MOG FC caused by reflexological foot stimulation was examined before age of 3 months and after the age of 6 and 9 months. Compared with control groups, the MTG FC of the infant in the case study is more significantly increased, whereas MOG FC in control is significantly less increased. This suggests MTG and MOG networks play different roles in language development. The increase of MTG FC is linked to good speech perception development, while increased MOG FC indicates poor speech perception development. Our study also shows that the functional status of the MOG and MTG may be used topredict the recovery of speech in CI users.
Contingencies of Climate Geoengineering and Moral Hazard
Authors: Sie Amanda , Brechin Steven R. , Borick Christopher P. 
Published: February 2023

Abstract
Geoengineering (GE) represents technologies designed to address the impacts of climate change. Two major research priorities have emerged. The first is the public’s understanding of and preferences for specific GE approaches and their perceived risks. The second is the moral hazard potential, or the preference for technological fixes that may disincentivize mitigation efforts focused on eliminating reliance on fossil fuels. We extend current research to explore the US public’s preferences for different GE approaches, and whether they predict moral hazard beliefs. We use data from the 2020 National Survey on Energy and the Environment, a nationally representative survey, and employ multinominal logistic regressions to examine the factors that predict prioritization of GE over mitigation. Our findings begin to solve the moral hazard riddle, suggesting a contingency model. We find that trust in scientists, conservative political beliefs, being non-White, and support for stratospheric aerosol injections and ambient air capture positively predicted selecting GE over standard mitigation efforts. The findings suggest that within the US context, moral hazard concerns should be directed towards a specific contingency. Moral hazard may also only be a concern for those who have lower climate risk perceptions but are forced to make climate policy choices. Further research is needed to explain the potential drivers of moral hazard beliefs, both in the US as well as beyond North American and OECD countries.
Head-to-head comparison of [68Ga]Ga-DOTA.SA.FAPi with [18F]F-FDG PET/CT in radioiodine-resistant follicular-cell derived thyroid cancers
Authors: Ballal Sanjana , Yadav Madhav , Wakade Nicky , Roesch Frank , Moon Euy Sung , Martin Marcel , Sheokand Parvind , Agarwal Shipra , Tripathi Madhavi , Sahoo Ranjit Kumar , Bal Chandrasekhar 
Published: February 2023

Abstract
Purpose
[18F]F-FDG is a standard and valuable diagnostic imaging modality for radioiodine-resistant follicular-cell derived thyroid cancers (RAI-R FCTC). Recently, molecular imaging probes targeting cancer-associated fibroblasts (CAFs) have gained prominence and have proved to be a potential alternative to [18F]F-FDG PET/CT in oncological imaging. This study aimed to compare the diagnostic efficacy of [68Ga]Ga-DOTA.SA.FAPi and [18F]-FDG PET/CT in RAI-R FCTC patients.
Methods
The retrospective study included 117 RAI-R FCTC patients [68 females, 49 males; mean age: 53.2 ± 11.7 years]. Qualitative assessment parameters included comparing patient-based and lesion-based visual interpretation of both scans. The quantitative assessment included comparing standardized uptake values corrected for lean body mass (SULpeak and SULavg). The findings on both scans were validated with the morphological findings of the diagnostic computed tomography.
Results
60 had single remnants, and 9 had bilateral remnant lesions with a complete concordance in the detection rate on both PET scans. [68Ga]Ga-DOTA.SA.FAPi showed a higher detection efficiency rate for lymph nodes (sensitivity 95.4% vs 86.6%, p < 0.0001), liver metastases (100% vs. 81.3%; p < 0.0001), brain metastasis (100% vs. 43.4%; p-0.0003). Except for brain metastasis (SULpeak [68Ga]Ga-DOTA.SA.FAPi vs. [18F]-FDG: 13.9 vs. 6.7) and muscle metastasis (SULpeak FAPI vs. FDG: 9.56 vs. 5.62), there was no significant difference in the median SUL uptake values between the radiotracers.
Conclusion
[68Ga]Ga-DOTA.SA.FAPi showed a superior detection efficiency for lymph nodes, liver, bowel, and brain metastasis. Unlike [18F]F-FDG, [68Ga]Ga-DOTA.SA.FAPi can be used as theranostic probes in RAI-R FCTC. [68Ga]Ga-DOTA.SA.FAPi provided a complimentary benefit to the [18F]F-FDG-PET/CT scan in the imaging of RAI-R FCTC.
ANN Based Estimation of Pore Pressure of Hydrocarbon Reservoirs - A case study
Authors: Kianoush Pooria , Mohammadi Ghodratollah , Hosseini Seyed Aliakbar , Khah Nasser Keshavarz Faraj , Afzal Peyman 
Published: February 2023

Abstract
In seismic methods, pore pressure is estimated by converting seismic velocity into pore pressure and calibrating it with pressure results during the well-testing program. This study has been carried out using post-stack seismic data and sonic and density log data of 6 wells in one of the fields in SW Iran. While an optimum number of attributes is selected, the General regression (GRNN) provides higher accuracy than Back Propagation (BPNN) at the initial prediction stages. However, Acoustic Impedance (AI) is the most applicable seismic attribute used as root and reverses AI for estimating P-wave and density. Using a set of attributes can train the system to estimate the property. The correlation coefficient of actual and predicted P-wave using an AI seismic attribute has been calculated as 0.74 and the multi-attribute technique as 0.79. Also, density and three attributes reach from 0.57 to 0.60, which shows a better relationship between seismic attributes and density. After determining optimum layers with the principal components analysis (PCA), formation pressure was modeled with the feed forward-backpropagation (FFBP-ANN) method. Five information layers, including gamma, Vp, AI, density, and overburden pressure, have the most linear convergence with the initial pressure model and are used to modify the ANN model of effective pressure.
Modulation of Electronic Structure of Single-Atom Catalysts for Sustainable Production of Full-Spectrum Amines from Renewable Biomass
Authors: Liu Wu-Jun , Zhou Xiao , Min Yuan , Huang Jia-Wei , Chen Jie-Jie , Wu Yuen , Yu Han-Qing 
Published: February 2023

Abstract
Using renewable biomass to replace fossil resources for producing low-carbon-footprint but high-value chemicals is a sustainable approach to pursue a carbon-neutral society. Herein, a boron nitrogen doped carbon (BNC) confined Pd single atom catalyst (Pd SAs/BNC) is synthesized and used as a robust catalyst toward the reductive amination reaction to produce low-carbon-footprint amines from renewable biomass. Because of the finely tuned electron structure, the as-synthesized single atom catalyst delivers an ultrahigh turn-over frequency value (max. 1368 h− 1) in the reductive amination of aldehydes/ketones and demonstrates a great conversion capacity for various aldehyde/ketone and amine/nitro-compound substrates. Extensive characterizations and density functional theory calculations show that the highly polar metal-N site formed between the central Pd single atom and its neighboring N and B atoms favors hydrogen activation from the donor (reductants) and hydrogen transformation to the receptor (C = O group), resulting in a great selectivity. This system could be further extended to directly produce various aromatic and furonic amines from renewable lignocellulosic biomass, and their greenhouse gas emission potentials are negative compared to those of fossil-fuel resource-based amines. This work offers a highly efficient and sustainable approach to construct C-N bonds for the production of numerous amines from carbon-neutral biomass resources.
The prognostic analysis of non-small cell lung cancer with unexpected pleural cavity dissemination
Authors: Wang Guige , Guo Chao , Ren Tianyao , Li Shanqing 
Published: February 2023

Abstract
Background: The prognosis of advanced non-small cell lung cancer (NSCLC) is poor. At present, incidental pleural cavity dissemination during operation is still unavoidable. The clinicopathological features and the best way to deal with incidental pleural cavity dissemination during operation has not been determined.
Methods: 58 NSCLC patients with pleural cavity disseminated incidentally found during surgery were included in our retrospective research from December 2012 to August 2018 according to the 8th edition of TNM staging. None of these had distant metastasis.
Results: Univariate and multivariate analysis revealed that targeted therapy was the only predictor of prognosis. Among patients receiving lymph node sampling or dissection, univariate analysis revealed that more advanced stage, lymph node metastasis, and higher proportion of metastatic lymph nodes were associated with worse progression-free survival (PFS). Smoking, more advanced stage, higher proportion of metastatic lymph nodes and no targeted therapy were significantly associated with worse overall survival (OS). Multivariate analysis recognized targeted therapy as the only predictor of prognosis. In patients not receiving targeted therapy, pleural cavity infusion chemotherapy seemed to be beneficial both to PFS and OS, but without statistical significance. Multivariate analysis found that lymph node metastasis was the only predictor of PFS, but no predictor of OS.
Conclusions: Targeted therapy is the best treatment for NSCLC patients with incidentally pleural cavity dissemination if there was target gene mutation. Pleural cavity infusion chemotherapy has potential survival benefit for patients without target gene mutations. Lymph node metastasis is not beneficial to the prognosis of patients with pleural cavity dissemination.
Short-term effects of sunn hemp intercropping management in a maize-based system on the soil fertility of a Plinthic Cambisol in Free State, South Africa
Authors: Gura Isaac , Dzvene Admire , Tesfuhuney Weldemichael , Walker Sue , Ceronio Gert 
Published: February 2023

Abstract
Intercropping is a promising strategy of improving soil fertility in no-till rainwater harvesting practices. However, the effect of intercropping forage legumes at various planting times and densities on soil fertility response under the in-field rainwater harvesting (IRWH) technique remains unknown in South Africa. The objective of this study was to determine the seasonal effect of sunn hemp (Crotalaria juncea L.) intercropping at different planting periods and densities into maize (Zea mays L.) after two growing seasons on selected soil fertility of a Plinthic Cambisol in Free State, South Africa. The experiment was a randomized complete block design with a factorial combination replicated thrice. The factorial combination consisted of three sunn hemp plantings dates viz., at maize planting, planting at V15 maize growth stage, and R1 maize growth stage, and three sunn hemp planting densities viz., 16.1 plants m− 2, 32.1 plants m− 2, and 48.1 plants m− 2. The results showed that the interaction of sunn hemp planting date and density was significant (p < 0.05) on soil organic matter (SOM) and Zinc (Zn). The growing season had a significant impact on changes in SOM, nitrogen (N), potassium (K), calcium (Ca), sodium (Na), manganese (Mn), and iron (Fe). Due to the intercropping periods and planting densities, the retention of sunn hemp residues with varying quantities and qualities may have influenced the soil nutrient dynamics in the short-term. Significant changes in soil fertility may take longer, and future research should be carried out in agricultural regions with different soil mineral matrices.
The effect of scenario-based training on the Core competencies of nursing students
Authors: Sadeghi Mohammad , Nematollahi Monirsadat , Farokhzadian Jamileh , Khoshnood Zohreh , Eghbalian Mostafa 
Published: February 2023

Abstract
Introduction

Competency is defined as the variety of skills and knowledge required to perform a specific task. Due to the specificity of pediatric nursing, students face some challenges in acquiring core competencies. Therefore, the use of new training methods in pediatric nursing is necessary. One of the modern learning methods is learning based on clinical scenarios. Thus, this study aimed to investigate the effect of scenario-based education on the core competencies of nursing students.

Method

This quasi-experimental study employed a pre-test and post-test design. All participants (n = 72) were selected via the census method and randomly divided into intervention (N = 33) and control groups (N = 40). The data were collected using a demographic information questionnaire and the Nursing Students' Clinical Competencies Questionnaire. Before the intervention, both groups completed the pre-tests. After one month, the students in both groups completed post-tests.

Results

The average score of core competencies for the students in the intervention group after the training (247.05, SD = 36.48) increased compared to before the intervention (229.05, SD = 36.58) (P > 0.05). The average score of the core competencies for the students in the control group after the training was 237.05 (SD = 36.33) compared to 235.56 (SD = 27.94) before the intervention, with no significant difference (P < 0.05). The independent t-test did not show a significant difference between the control and intervention groups before and after the intervention (P > 0.05).

Conclusion

The results indicated the effectiveness of scenario-based training on the core competencies of students in the intervention group. Accordingly, nursing administrators and professors are recommended to incorporate new scenario-based teaching and learning methods in educational programs of universities. It is also necessary to conduct more research into the effectiveness of this method in combination with other training methods like team-based and problem-based training.
Flash flooding in semiarid alluvial fan apron systems: processes, forms and human activity interactions in the Menor Sea basins (Spain)
Authors: Muñoz-López Fernando , beltran francisca Segura segura , Bersi Mohand , Sanchis-Ibor Carles 
Published: February 2023

Abstract

This paper presents a holistic analysis of the September 12–15, 2019, flash flood in the Mar Menor basin (Spain). The research aims to analyse the causal factors, define the flooding processes and establish criteria to detect the active zone in highly anthropized alluvial apron systems. For this purpose, several data sources were combined: digital elevation models, ortophotos, precipitation and gauging data, geomorphological and flood hazard mapping and second-generation Sentinel-2 images, which were interpreted using a turbid water index. Results allow a complete characterization of flash flood processes in alluvial fan apron systems and highlight different behaviors in the different sectors of these complex fan systems. They show an important discrepancy between the actual flood processes and the official hazard mapping, which highlights the need to develop quali-quantitative approaches to better understand flood processes in alluvial apron systems. The research also shows that floods in Mediterranean alluvial apron systems must be considered as mixt processes, resulting of nature and culture interactions, because of the longstanding tradition of runoff use and management through different traditional infrastructures. Future flood mitigation strategies should recover or imitate these ancestral solutions and should lead to a radical change in urban planning design on these areas.