bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multimodal Sensing in Stroke Motor Rehabilitation
Authors: Zhao Zihe , Wang Jiaqi , Wang Shengbo , Wang Rui , Lu Yao , Yuan Yan , Chen Junliang , Dai Yanning , Liu Yong , Wang Xiaomeng , Pan Yu , Gao Shuo 
Published: March 2023

AbstractApplying sensors in biomedical institutions and home‐based stroke rehabilitation is now a global research focus. In this review paper, the relationship between stroke diseases’ physiology mechanism and diverse sensors’ functionalities is detailed explained. The review starts by interpreting how stroke influences motion abilities and then introduces broadly adopted physical training methods. After, the working principles of sensors and their use to objectively provide patients’ body information for stroke rehabilitation status are discussed. The content of the paper aims to not only review the state‐of‐the‐art works of developing sensors for assisting in evaluating stroke patients’ status but also bridging the gap between medical staff and engineers.
DNA Composites and Applications in Bioanalysis
Authors: Fang Zheng , Li Min , Zuo Xiaolei 
Published: March 2023

AbstractDNA combined with other functional nanomaterials plays crucial roles in biomedical areas, including bio‐detection, bioimaging, as well as disease diagnosis and treatment. Rapid advances in DNA composites for biological applications have been achieved during the past few decades. In this review, it is first summarized the synthesis methods of DNA composites with inorganic core and organic core, as well as the applications of DNA composites in cancer diagnosis. The in vitro detection of various disease biomarkers and in vivo tumor imaging using DNA composites are introduced. Finally, main challenges and the new frontiers in the field of using DNA composites for cancer diagnosis are summarized.
Synthesis of a π‐Extended Double [9]Helicene
Authors: Tan Jingyun , Xu Xiushang , Liu Jun , Vasylevskyi Serhii , Lin Zesen , Kabe Ryota , Zou Yingping , Müllen Klaus , Narita Akimitsu , Hu Yunbin 
Published: March 2023

AbstractDouble helicenes are appealing chiral frameworks. Their π‐extension is desirable to achieve (chir)optical response in the visible and near‐infrared (NIR) region, but access to higher double [n]helicenes (n≥8) has remained challenging. Herein, we report an unprecedented π‐extended double [9]helicene (D9H), unambiguously revealing its structure by single‐crystal X‐ray diffraction.D9Hshows remarkable NIR emission from 750 to 1100 nm with a high photoluminescence quantum yield of 18 %. In addition, optically pureD9Hexhibits panchromatic circular dichroism with a notable dissymmetry factor (gCD) of 0.019 at 590 nm, which is among the highest in the visible region for reported helicenes.
Copper‐Catalyzed Enantioselective Trifluoromethoxylation of Propargyl Sulfonates
Authors: Hou Yangdong , Zhang Zhang , Sun Xinyu , Yang Zheng , Luan Yu‐Xin , Tang Pingping 
Published: March 2023

AbstractDue to the strong electron‐withdrawing nature and high lipophilicity of trifluoromethoxy group (OCF3), methods for introducing OCF3into organic molecules are in high demand. However, the research area of direct enantioselective trifluoromethoxylation is still in the embryonic stage, with limited enantioselectivity and/or reaction types. Here, we describe the first copper‐catalyzed enantioselective trifluoromethoxylation of propargyl sulfonates using trifluoromethyl arylsulfonate (TFMS) as the trifluoromethoxy source in up to 96 % ee.
A Heptacene Analogue Entailing a Quinoidal Benzodi[7]annulene (7/6/7 Ring) Core with a Tunable Configuration and Multiple Redox Properties
Authors: Huang Yan‐Ying , Wu Botao , Shi Dandan , Liu Dan , Meng Wei , Ma Junlong , Qin Liyuan , Li Cheng , Zhang Guanxin , Zhang Xi‐Sha , Zhang Deqing 
Published: March 2023

AbstractNon‐benzenoid acenes containing heptagons have received increasing attention. We herein report a heptacene analogue containing a quinoidal benzodi[7]annulene core. Derivatives of this new non‐benzenoid acene were obtained through an efficient synthetic strategy involving an Aldol condensation and a Diels–Alder reaction as key steps. The configuration of this heptacene analogue can be modulated from a wavy to a curved one by just varying the substituents from a (triisopropylsilyl)ethynyl group to a 2,4,6‐triisopropylphenyl (Trip) group. When mesityl (Mes) groups are linked to the heptagons, the resulting non‐benzenoid acene displays polymorphism with a tunable configuration from a curved to a wavy one upon varying the crystallization conditions. In addition, this new non‐benzenoid acene can be oxidized or reduced by NOSbF6 or KC8 to the respective radical cation or radical anion. Compared with the neutral acene, the radical anion shows a wavy configuration and the central hexagon becomes aromatic.
Polymerization Strategies to Construct a 3D Polymer Passivation Network toward High Performance Perovskite Solar Cells
Authors: Liu Dachang , Wang Xiao , Wang Xianzhao , Zhang Bingqian , Sun Xiuhong , Li Zhipeng , Shao Zhipeng , Mao Sui , Wang Li , Cui Guanglei , Pang Shuping 
Published: March 2023

AbstractThe spontaneously formed uncoordinated Pb2+ defects usually make the perovskite films demonstrate strong n‐type with relatively lower carrier diffusion length and serious non‐radiative recombination energy loss. In this work, we adopt different polymerization strategies to construct three‐dimensional passivation frameworks in the perovskite layer. Thanks to the strong C≡N⋅⋅⋅Pb coordination bonding and the penetrating passivation structure, the defect state density is obviously reduced, accompanied by a significant increase in the carrier diffusion length. Additionally, the reduction of iodine vacancies also changed the Fermi level of the perovskite layer from strong n‐type to weak n‐type, which substantially promotes the energy level alignment and carrier injection efficiency. As a result, the optimized device achieved an efficiency exceeded 24 % (the certified efficiency is 24.16 %) with a high open‐circuit voltage of 1.194 V, and the corresponding module achieved an efficiency of 21.55 %.
Multi‐Stimuli Responsive Luminescence and Domino Phase Transition of Hybrid Copper Halides with Nonlinear Optical Switching Behavior
Authors: Wu Jiajing , Guo Yue , Qi Jing‐Li , Yao Wen‐Dong , Yu Su‐Xin , Liu Wenlong , Guo Sheng‐Ping 
Published: March 2023

AbstractAlthough phase transition materials (PTMs) under external stimuli are of great research interest duo to their rich potential applications, it is still challenging to explore multi‐responsive PTMs. Herein, two different phases of organic–inorganic hybrid copper‐based halides, α‐ and β‐Gua3Cu2I5(Gua+=CN3H6+), were synthesized by solvent evaporation method, which they crystalize in the noncentrosymmetric space groupFdd2 with zero‐dimensional structure and centrosymmetric space groupC2/cwith one‐dimensional metal‐halogen framework, respectively. Interestingly, it is firstly demonstrated that Gua3Cu2I5simultaneously possesses reversible PL conversion and NLO switching properties in response to thermal stimulus. Strikingly, apart from heat, its structural phase transition can also be triggered by crystalline‐phase‐recognition (CPR) and mechanical force. These new findings may pave a path for future exploration of PTMs with multiple physical properties.
Dialogue and creativity: The generative dialogical perspective in therapy
Authors: Schnitman Dora Fried 
Published: March 2023

AbstractThe generative perspective in therapy understands relations and dialogue as a generative social space where participants can promote innovative resources and possibilities for themselves, and their relations and circumstances, along with new social ecologies. It focuses on the creative dimensions of human relationality. This epistemological and clinical perspective has a heuristic value that allows us to discern and work with micro dialogues—micro processes of creative, generative dialogues—in the ongoing dialogue, mindful of the opportunities for creativity and innovation they provide. The generative perspective promotes creative processes and transformations to help clients build possible and viable futures when faced with problems, conflicts and challenges. It involves the dialogical and relational co‐creation of resources and possibilities, and actions for implementation. The perspective is illustrated with a therapy process involving a 3‐year follow‐up. The paper includes a section where differences and similarities between dialogical perspectives are presented.
Analog Quantum Valley–Hall and Quantum Spin Hall Plasmons in Graphene Metasurfaces with Low Point Group Symmetry
Authors: Chen Long , Lan Zhihao , Wu Xiong Wei , Ma Qian , You Jian Wei , Cui Tie Jun 
Published: March 2023

AbstractIn recent years, topological physics of classical waves in artificial crystals has become an emerging field of research. While Dirac cones and valley‐related physics are conventionally studied in these systems with C6v and C3v point‐group symmetries, here analog quantum valley Hall and quantum spin Hall plasmons in graphene metasurfaces with lower point‐group symmetries are explored. First, it is shown that a single‐layer graphene sheet with rectangle holes respecting to the C2v point group symmetry can host a mirror (σv) symmetry‐protected Dirac cone along the X–M edge of the Brillouin zone. Then we demonstrate that introducing further circular holes to the graphene sheet can break the mirror symmetry (i.e., reducing C2v symmetry to C1v) and thus gap out the Dirac cone, which allows us to explore the valley and layer‐pseudospin related topological plasmons in these graphene metasurfaces with low point group symmetry. Valley‐locking unidirectional propagations along the domain–wall interface of a single‐layer graphene metasurface and layer‐pseudospin converter in a double‐layer graphene metasurface are explicitly demonstrated for graphene plasmons in the THz range. This work provides a new design principle for exploring Dirac cones, valley, and pseudospin related physics using much lower point‐group symmetries.
Advances in Synthetic Biology of Fungi and Contributions to the Discovery of New Molecules
Authors: Valiante Vito 
Published: March 2023

AbstractThe sequencing of fungal genomes is becoming increasingly accessible, with a wealth of data already available. In parallel, the prediction of the putative biosynthetic pathways responsible for the synthesis of potential new natural products is also increasing. The difficulty of translating computational analyses into available compounds is becoming evident, slowing down a process that was thought to be faster with the advent of the genomic era. Advances in gene techniques made it possible to genetically modify a wider range of organisms, including fungi typically considered recalcitrant to DNA manipulation. However, the possibility of screening many gene cluster products for new activities in a high‐throughput manner remains unfeasible. Nonetheless, some updates on the synthetic biology of fungi could provide interesting insights that could help to achieve this goal in the future.
COL11A1‐driven positive feedback loop modulates fibroblast transformation and activates pancreatic cancer progression
Authors: Sun Defeng , dai Tu , Ji Yuan , Shen Weibo , Bian Wuyang 
Published: March 2023

AbstractPancreatic ductal adenocarcinoma (PDAC) is one of the most common leading causes of cancer death. The cancer‐associated fibroblasts (CAFs) in the tumor microenvironment (TME) aggravate the malignant behavior of PDAC. However, it is still unknown how PDAC induces normal fibroblasts (NFs) to CAFs. In present research, we found that PDAC‐derived collagen type XI alpha 1 (COL11A1) promoted the conversion of NFs to CAF‐like cells. It included morphological and corresponding molecular marker changes. Activation of the nuclear factor‐κB (NF‐κB) pathway was involved in this process. Corresponding, CAFs cells could secrete interleukin 6 (IL‐6), which promoted the invasion and the epithelial‐mesenchymal transition of PDAC cells. Furthermore, IL‐6 promoted the expression of transcription factor Activating Transcription Factor 4 by activating the Mitogen‐Activated Protein Kinase/extracellular‐signal‐regulated kinase pathway. The latter directly promotes the expression of COL11A1. This way, a feedback loop of mutual influence was constructed between PDAC and CAFs. Our research proposed a novel concept for PDAC‐educated NFs. PDAC‐COL11A1‐fibroblast‐IL‐6‐PDAC axis might contribute to the cascade between PDAC and TME.
Concurrent hypereosinophilic syndrome and deep vein thrombosis after Pfizer‐BioNTech COVID‐19 vaccination: A case report
Authors: Yano Shungo , Miyagami Taiju , Furusaka Takayuki , Kano Nagamasa , Naito Toshio 
Published: March 2023

AbstractHerein, we report a case of eosinophilia syndrome and deep vein thrombosis presenting concurrently after the administration of the BNT162b2 mRNA‐based coronavirus disease 2019 (COVID‐19) vaccine. It is extremely rare to have both hypereosinophilic syndrome and deep vein thrombosis simultaneously. Both are serious diseases and should be treated with caution.
In Situ Generation of Pt2Co3 Nano‐Alloys in Porous N‐Doped Carbon for Highly Efficient Electrocatalytic Hydrogen Evolution
Authors: Li Bing , Wang Leiyu , Liu Huijing , Chen Jing , Xie Jianhui , Liu Yingying , Lau Tai‐Chu 
Published: March 2023

AbstractPlatinum (Pt) catalysts are the state‐of‐the‐art electrocatalysts for hydrogen evolution reaction (HER), but it is still a challenge to improve the utilization efficiency and stability of Pt‐based catalysts. Herein, Pt2Co3 nano‐alloys anchored on the surface of the N‐doped carbon support are precisely synthesized via metal complex‐controlled pyrolysis. Benefiting from the formation and exposure of the bimetallic nano‐alloys, the optimal Pt2Co3/NC‐950 electrocatalyst exhibits an extraordinary HER catalytic activity and stability. To achieve a current density of 10 mA cm−2, the Pt2Co3/NC‐950 electrocatalyst requires small overpotentials of 12 mV in both acidic and alkaline media with small Tafel slopes of 6 mV dec−1 and 24 mV dec−1 in 0.5 M H2SO4 and 1 M KOH, respectively, which is superior to the commercialized Pt/C catalyst. Additionally, the much higher turnover frequencies and the larger electrochemical surface areas of Pt2Co3/NC‐950 further reveal its superior catalytic active sites. Based on theoretical calculations, the outstanding HER activity is found to be attributed to the synergic effect of the Pt and Co components that optimizes the adsorption Gibbs free energy of hydrogen atom and accelerates water dissociation in alkaline media.
In situ Generation of Intimacy in MnOx+SAPO‐34 Mechanical Mixture for the Conversion of Syngas to Light Olefins
Authors: Coudercy Christophe , Prevot Mathieu S. , Afanasiev Pavel , Loridant Stéphane 
Published: March 2023

AbstractBifunctional MnOx+SAPO‐34 catalysts were evaluated for the conversion of syngas to light olefins (OXZEO process). They were prepared, either by mechanical mixing of 100 μm‐scale particles agglomerates, or by mixing of ethanol suspensions, containing homogeneously distributed micrometer‐scale primary particles of oxide and zeolite. The selectivity to light olefins, initially lower for the mechanical mixture, reached the value of the suspension mixture after a 14 h on‐stream period. This convergence was explained from SEM images by in situ breaking of SAPO‐34 agglomerates present in the mechanical mixture and dispersion of SAPO‐34 crystals among MnOx primary particles, decreasing the contact distance between the two catalytic functions. These results evidence the importance of intimacy at the micrometer scale to improve the catalytic properties in the OXZEO process.
Boosting Hydrostability and Carbon Dioxide Capture of Boroxine‐Linked Covalent Organic Frameworks by One‐Pot Oligoamine Modification
Authors: Jia Chao , Liang Rong‐Ran , Gan Shi‐Xian , Jiang Shu‐Yan , Qi Qiao‐Yan , Zhao Xin 
Published: March 2023

AbstractBoron‐based covalent organic frameworks (COFs) are susceptible to nucleophilic attack by water at the electron‐deficient boron sites and even slightly humid air could destroy the integrity of their porous frameworks within hours. Such instability is a major limitation to the practical applications of boron‐based COFs. Herein we report a significant enhancement of hydrostability of boroxine‐linked COFs (COF‐1 as representative) by modification with an oligoamine (tetraethylenepentamine, TEPA), which leads to survival of the modified COF in water and long‐time stability under humid atmosphere. Meanwhile, the TEPA modification also results in a considerable increase in CO2 adsorption capacity up to 13 times and a dramatic improvement in CO2/N2 selectivity in low pressure region, which make the modified COF suitable for capturing CO2 from flue gas. This work provides a facile, efficient, and scalable method to greatly improve hydrostability of boroxine‐linked COFs and reshape them into high‐performance CO2 adsorbents.
Liquid Dynamics Determine Transition Metal‐N‐Heterocyclic Carbene Complex Formation
Authors: Zaby Paul , Blasius Jan , Müller Anna K. , Nolan Steven P. , Hollóczki Oldamur 
Published: March 2023

AbstractInvited for the cover of this issue are Oldamur Hollóczki and co‐workers at the Universities of Bonn, Ghent and Debrecen. The image depicts the search of an ionic base for the acidic proton of an imidazolium cation in order to form a carbene complex. Read the full text of the article at 10.1002/chem.202203636.
Comprehensive Parameter Screening for the Investigation of Particulate Fouling in Pipe Fittings
Authors: Jarmatz Niklas , Augustin Wolfgang , Scholl Stephan 
Published: March 2023

AbstractA prominent example of unwanted accumulation in production plants is particulate fouling, which has been subject of many studies in apparatuses. However, pipe fittings have attracted little attention despite their large number in production plants. Here, the influence of process parameters and geometry factors on the fouling in pipe fittings is investigated under isothermal conditions that aims to an improved understanding of their fouling behavior. The variation of fitting type and size, the run time and particle mass fraction have the greatest impact on the fouling mass while the temperature does not influence the result.
Spatially Resolved Temperature Measurements during Condensation in Presence of a Non‐Condensable Gas
Authors: Schwerdtfeger Natalie , Schulte Annalena , Jasch Katharina , Scholl Stephan 
Published: March 2023

AbstractAxial temperature profiles of the vapor phase can provide valuable indication of the condensation process along the heat transfer path and highlight the impact of non‐condensable gases on a unit's performance. The local measurements at moderate vacuum conditions for condensation of a binary mixture are presented alongside the implementation and assessment of optical sensors in a heat transfer process. The results show a good depiction of the characteristic temperature behavior during the condensation process. The relation between temperature, partial pressure and mole fractions are shown.
Simulation analysis of gas–solid flow characteristics and water evaporation in flue gas semi‐dry desulphurization process based on CPFD method
Authors: Liu Peng , Wu Xuan , Li Haiguang , Bo Yuxuan , Wei Nan 
Published: March 2023

AbstractThe gas–solids flow in an industrial‐scale semi‐dry method desulphurization tower is simulated by the computational particle fluid dynamics (CPFD) approach. Compared with previous studies on desulphurization towers, this study focuses on analyzing particle distribution characteristics such as particle volume fraction, temperature distribution, and residence time. The simulation fully considered the particle–fluid, particle–particle, and particle–wall interactions in the desulphurization tower. Based on these considerations, the effects of flue gas inlet velocity and temperature on the gas–solid distribution characteristics of the desulphurization tower are simulated. An optimization scheme for adjusting the gas–solid flow in the desulphurization tower is proposed. The research results show that the error between the CPFD simulation data and experimental data is small and the changing trend is consistent. The particles in the bed of the desulphurization tower show a typical core–annulus flow. The distribution of gas and particles in the bed has a serious deviation with the increase of the flue gas inlet velocity and temperature. As the axial height of the desulphurization tower increases, the flue gas velocity, temperature, particle concentration, and water vapour distribution in the bed become more uniform. The relatively stable operating conditions for the gas–solid flow in the desulphurization tower is that the flue gas inlet velocity and temperature are 15 m/s and 393 K, respectively. Under these operating conditions, the pressure loss caused by the venturi accounted for 73.6% of the total pressure loss of the desulphurization tower. When the particle radius is between 0–150 μm, the particle size and the flue gas inlet velocity have the greatest influence on the particle residence time. Finally, the distribution of gas and particles before and after the adjustment of the desulphurization tower is compared, which showed that adjusting the bottom structure of the desulphurization tower could optimize the gas–solid flow.
PROTOCOL: Domestic abuse interventions for mothers in or exiting prison: An evidence and gap map
Authors: Rogers Michaela , Lockwood Kelly , Speake Elizabeth , Campbell Fiona 
Published: March 2023

AbstractThis is the protocol for a evidence and gap map. The objectives are as follows: to identify existing research and gaps in evidence according to the types of interventions, settings, study design and outcomes; to use the EGM findings to inform subsequent systematic reviews and to identify gaps in evidence to inform future research, policy or practice.
Coupling Dielectric Functionality with Magnetic Properties in Coordination Metal Complexes
Authors: Sekine Yoshihiro , Nakamura Rikuto , Akiyoshi Ryohei , Hayami Shinya 
Published: March 2023

AbstractSignificant research has been conducted on molecular ferroelectric materials, including pure organic and inorganic compounds; however, studies on ferroelectric materials based on coordination metal complexes are scarce. Ferroelectric materials based on coordination metal complexes have tunable structures and designs, with coexistence or synergy between the ferroelectric behavior and magnetic properties. Compared to inorganic compounds, few coordination metal complexes exhibit coupling between the magnetic and dielectric properties. Coordination metal complexes with strong coupling between the magnetic and dielectric properties exhibit dielectric permittivity variations under external magnetic fields. Therefore, they have attracted substantial interest for their potential use in magnetoelectric devices. In this review, we discuss recent advances in coordination metal complexes, that exhibit coupled magnetic functionalities and ferroelectricity or dielectric properties, including single‐molecule magnets, electron delocalization systems, and external stimuli responsive compounds.