bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Needs, ACUTE Response: Development and Delivery of a Mental Health Urgent Care in the Bronx
Authors: DuPerry Kahlil C. , Siber-Sanderowitz Shaina , Hill Elisabeth , Cintron-Arroyo Melissa , Glasgow Allison , Vileisis Julia 
Published: January 2025

AbstractAs mental health needs rise, creative and timely solutions are essential. Leveraging the expansion and flexibility of virtual services to create telehealth and hybrid offerings is crucial for addressing systemic barriers in mental health, enhancing accessibility, and providing flexible, comprehensive care options for diverse patient populations. This article discusses the development of a mental health urgent care program within a large medical system in a densely populated, under-resourced community. The program was designed to address common community mental health barriers across multiple care entry points, including ambulatory settings, emergency care, and consultation services. Using a multipronged approach, this program aims to improve patient access, care continuity, and outcomes. The authors encourage others to consider adopting a similar programmatic infrastructure to reduce mental health care barriers in their communities.
The Dutch Early-Stage Melanoma (D-ESMEL) study: a discovery set and validation cohort to predict the absolute risk of distant metastases in stage I/II cutaneous melanoma
Authors: Zhou Catherine , Mooyaart Antien L. , Kerkour Thamila , Louwman Marieke W. J. , Wakkee Marlies , Li Yunlei , Voorham Quirinus J. M. , Bruggink Annette , Nijsten Tamar E. C. , Hollestein Loes M. 
Published: January 2025

Abstract
Early-stage cutaneous melanoma patients generally have a favorable prognosis, yet a significant proportion of metastatic melanoma cases arise from this group, highlighting the need for improved risk stratification using novel prognostic biomarkers. The Dutch Early-Stage Melanoma (D-ESMEL) study introduces a robust, population-based methodology to develop an absolute risk prediction model for stage I/II melanoma, incorporating clinical, imaging, and multi-omics data to identify patients at increased risk for distant metastases. Utilizing the Netherlands Cancer Registry and Dutch Nationwide Pathology Databank, we collected primary tumor samples from early-stage melanoma patients, with and without distant metastases during follow-up. Our study design includes a discovery set of metastatic cases and matched controls to identify novel prognostic factors, followed by a validation cohort using a nested case–control design to validate these factors and to build a risk prediction model. Tissue sections underwent Hematoxylin & Eosin (H&E) staining, RNA sequencing (RNAseq), DNA sequencing (DNAseq), immunohistochemistry (IHC), and multiplex immunofluorescence (MxIF).The discovery set included 442 primary melanoma samples (221 case–control sets), with 46% stage I and 54% stage II melanomas. The median time to distant metastasis was 3.4 years, while controls had a median follow-up time of 9.8 years. The validation cohort included 154 cases and 154 controls from a random population-based selection of 5,815 patients. Our approach enabled the collection of a large number of early-stage melanoma samples from population-based databases with extensive follow-up and a sufficient number of metastatic events. This methodology in prognostic cancer research holds the potential to impact clinical decision-making through absolute risk prediction.
Components of Empathy in Children: Factor Structure of the Empathy Quotient for Children (EQ-C)
Authors: Smees Rebecca , Rinaldi Louisa J. , Simner Julia 
Published: January 2025

AbstractEmpathy is multifaceted, involving sharing and understanding the emotional and mental states of others. This study investigated the factor structure of the English-language version of the Empathy Quotient for Children (EQ-C; Auyeung et al., 2009), an empathy measure previously well-validated only as a global scale. We aimed to compare children with and without educational differences (i.e., Special Educational Needs & Disabilities, SEND), and explored associations between empathy and sensory sensitivities across the whole sample. Based on responses from 680 parents, we analysed data from English-speaking children aged 6–12 years, via a series of factor analyses using polychoric correlation matrices and bass-ackward analysis. Empathy domain profiling for children with SEND status (versus children without SEND status) was investigated as group differences (t tests). Sensory sensitivities were examined via associations (correlation) and net effects (regression). We identified an optimal four-factor solution (emotional empathy, social-cognitive empathy, negative interactions, antisocial behaviours), and robust higher order one-, two- and three-factor models. Children with SEND status displayed empathy differences across all four empathy domains (all p < .001). Children with greater sensory sensitivities displayed significant differences for social-cognitive empathy and negative interactions only (both p < .001). We demonstrated the potential utility of the English-language EQ-C as a domain-level measure of empathy. Our paper discusses how the domains align with traditional emotional and cognitive dimensions in adults and cross-culturally. Our empathy profiles can be used alongside global empathy measures for different groups of children, with and without educational differences and sensory sensitivities.
Single-shuffle card-based protocol with eight cards per gate and its extensions
Authors: Tozawa Kazunari , Morita Hiraku , Mizuki Takaaki 
Published: January 2025

AbstractCard-based cryptography allows us to securely compute arbitrary functions using a deck of physical cards. Its performance is mainly measured by the number of used cards and shuffles, and there is a line of work that aims to reduce either of them. One seminal work is the card-based garbled circuit technique by Shinagawa and Nuida (Discret Appl Math 289:248–261, 2021, https://doi.org/10.1016/j.dam.2020.10.013), which allows the construction of a card-based protocol for any Boolean function with a single shuffle. Their construction requires $$2n + 24g$$

2
n
+
24
g

cards for an n-input Boolean function that is represented by g logical gates. In this paper, we reduce the number of cards to $$2n + 8g$$

2
n
+
8
g

for arbitrary functions while keeping it working with only one shuffle. In addition, we propose two types of extensions to support numerical encoding and multi-input gates. In the extended scheme, the free-ADD technique, obtained by generalizing the free-XOR technique by Manabe and Shinagawa (Deng J, Kolesnikov V, Schwarzmann AA (eds) CANS 2023, LNCS, vol 14342. Springer, Singapore, pp 232–248, 2023, https://doi.org/10.1007/978-981-99-7563-1-11), is available. The free-ADD technique allows our scheme to evaluate any n-input symmetric Boolean function using $$2n^2+6n+2$$

2

n
2

+
6
n
+
2

cards.
Shift of the ecosystem nitrogen cycle from open to closed within a century along a glacial retreat chronosequence at Mount Gongga, southwest China
Authors: Basdediós Nuria , Hardegger Samuel , Mestrot Adrien , Wang Jipeng , Zhou Jun , Bing Haijian , Wu Yanhong , Wilcke Wolfgang 
Published: January 2025

Abstract
Aims
To improve our understanding of N cycle development during primary succession after glacial retreat, we (i) assessed the role of biological N2 fixation, (ii) determined gross ammonification rates to identify the onset of mineralization, (iii) quantified the retention of 15NH4+ and 15NO3− in various ecosystem compartments to evaluate the accumulation of deposited N and (iv) followed the 15NH4+ label into the soil NO3− pool to explore the development of nitrification along the subtropical alpine Hailuogou glacial retreat chronosequence, SW China.

Methods
We measured N stocks and δ15N values in the dominant tree species, organic layer and 0–10 cm of the mineral soil and quantified N turnover rates and accumulation via 15N tracer experiments.

Results
N accumulated in the ecosystem at a fast mean rate of 4.5 ± 1.0 g m−2 yr−1 favored by an initially near-neutral soil pH value. The δ15N values of the vegetation started near 0‰ and decreased to a range of -2.7 to -4.4‰ in 127 years. Gross ammonification rates were initially low but increased with ecosystem age from 0.025 to 50.6 mg kg−1 d−1 N, matching those of mature (sub)tropical forests. The maximum accumulation of deposited N shifted from the bryophyte via the shrub layer to the soil organic layer. The 15NH4+ label hardly appeared in the NO3− pool reflecting little nitrification.

Conclusions
Strong initial biological N2 fixation and retention of deposited N was succeeded by a tight N cycling between soil and vegetation at the older sites within approximately 120 yr.
Co-ensiling pomegranate (Punica granatum L.) peels and molasses with berseem (Trifolium alexandrinum L.) alters fermentation quality, nutrient composition, ruminal fermentation and methane production in buffalo bulls in-vitro
Authors: Ahmed Mariam G. , El-Zarkouny Samir Z. , Al-Sagheer Adham A. , Elwakeel Eman A. 
Published: January 2025

Abstract
Pomegranate peels are an industrial by-product high in sugar and phytochemical content and pose an environmental concern. Meanwhile, ensiling legume forage such as berseem is difficult due to its lower dry matter content and water-soluble carbohydrate-to-buffering capacity ratio, which leads to a poor fermentation process. To date, no studies have been conducted to investigate the effect of co-ensiling pomegranate peels with berseem. Thus, silage quality was evaluated after co-ensiling of berseem (control) with 50, 100, and 200 g/kg pomegranate peels or 50 g/kg molasses for 0, 15, 30, and 45 days (Experiment 1). Further, rumen nutrient degradation, methane production, and rumen fermentation parameters were evaluated in vitro (Experiment 2). Pomegranate peels (200 g/kg) and molasses reduced silage pH compared to control (4.41 or 3.79 vs. 5.02), ammonia-N (2.66 or 3.14 vs. 13.39 g/kg N), and butyric acid (0.05 or 0.1 vs. 0.96 g/kg DM) however, dry matter (323.5 or 283.6 vs. 212.8) and non-fiber carbohydrates (264.8 or 351.8 vs.136.9 g/kg) were increased, respectively. Pomegranate peels and molasses significantly (P < 0.05) increased rumen nutrient degradation and significantly (P < 0.05) decreased methane and ammonia-N production (Experiment 2). The chemical composition of silage, in-vitro rumen fermentation, and silage quality parameters were significantly (P < 0.05) correlated. Pomegranate peels and molasses have potentially improved silage quality and positively influenced rumen fermentation parameters.
Synthesis of Ionic Liquid-Assisted Nanoparticles: High Activity, Fast Removal for Photodegradation of Methylene Blue in Water
Authors: Hussain Mohamedalameen H. A. , Pozan SOYLU Gulin Selda 
Published: January 2025

Abstract
The discharge of dye residues from the textile industry is a major contributor to water pollution, highlighting the urgent need for effective wastewater treatment solutions. This study investigates the synthesis of ZnO and Bi₂O₃ nanoparticles using ionic liquid-assisted methods for enhanced photocatalytic degradation of methylene blue. Three ionic liquids were employed: 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM]-BF₄), 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM]-PF₆), and 1-butyl-3-methylimidazolium chloride ([BMIM]-Cl). The synthesized nanoparticles were characterized using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and photoluminescence (PL) spectroscopy. Results showed that ionic liquid incorporation led to improved crystallinity, uniform morphology, and reduced particle sizes. ZnO-[BMIM]-BF₄ (1%) and Bi₂O₃-[BMIM]-BF₄ (1%) exhibited the lowest band gap energies of 2.50 eV and 2.20 eV respectively, indicating enhanced light absorption. These catalysts also demonstrated superior photocatalytic activity, achieving complete degradation of methylene blue within 40 and 35 min under UV-B irradiation, and 60 min under sunlight. The enhanced performance was attributed to improved light absorption, reduced electron–hole recombination, and efficient charge transfer facilitated by the ionic liquids. The catalysts showed excellent stability over multiple degradation cycles. This study highlights the potential of ionic liquid-assisted synthesis in developing highly efficient and stable photocatalysts for environmental remediation applications.

Graphical Abstract
Assessing the feasibility of mapping changes of ecosystem functional groups in South African estuaries using Landsat and Sentinel images of 1990, 2014, 2018 and 2020
Authors: van Deventer Heidi , Apleni Philani , Adams Janine B. , Riddin Taryn , Whitfield Emily , Machite Anesu , van Niekerk Lara , Madasa Akhona 
Published: January 2025

AbstractThis study evaluates the feasibility of using medium-resolution satellite sensors to monitor changes in the extent of ecosystem functional groups (EFGs) in South African estuaries, for reporting on the 2030 targets of the Global Biodiversity Framework (GBF). Landsat and Sentinel-1 and -2 image collections in Google Earth Engine (GEE) were used to generate output layers for each of the national land cover years—1990, 2014, 2018 and 2020. Image composites of each year’s two growth seasons and one dry season, vegetation indices and topographic data were generated. Changes in the extent and accuracies of three estuarine (mangroves, salt marshes and submerged macrophytes) and three freshwater (forested wetlands, freshwater marshes and large macrophytes) EFGs were calculated and compared to a manually mapped through image interpretation, high-confidence layer. Overall, estuarine EFGs comprised between 10 and 18% of the extent of the EFGs, while freshwater EFGs made up 15% of the extent of estuaries. The overall accuracies of detection of EFGs for 1990 were < 64% compared to the > 71% attained for 2014, 2018 and 2020. In comparison to manual delineations of some of these habitats, the outputs generated from these medium-resolution sensors resulted in overestimation of extent for all EFGs; for mangroves by 115% and for salt marshes and submerged macrophytes by 150–230%. Finer spatial resolution images, and time-series mapping would be critical for improved delineation and monitoring of South Africa’s estuarine habitats.
Enhancement of aqueous solubility of icariside II through complexation and addition of Tween 80 and lecithin
Authors: Szabó Róbert , Rácz Csaba-Pál , Kacsó Irina , Dulf Francisc Vasile 
Published: January 2025

Abstract
Natural drug products with limited water solubility pose a challenge to the pharmaceutical industry in terms of developing an appropriate dissolution procedure. Like other flavonoids, icariside II (ICS) also faces challenges such as insufficient bioavailability caused by its poor water solubility, limiting its oral therapeutic applications as a food supplement. Consequently, new approaches are needed across the board focusing on the aqueous solubility enhancement. This work aimed to use whey protein concentrate (WPC) as a carrier, and surfactants such as Tween 80 and lecithin to improve the water solubility of icariside II. The complexation with WPC successfully increased the water solubility of ICS by approximately 258-fold. Furthermore, the incorporation of surfactants into the complex resulted in an even greater enhancement, achieving a 554-fold improvement. In addition, by repurposing of whey protein complexes, a byproduct generated during cheese production, and the application of efficient solvent recovery methods, we illustrate our dedication to sustainability. Fourier transform infrared spectroscopy; X-ray powder diffraction and differential scanning calorimetry indicated the successful complex formation procedure. Using a scanning electron microscope, the morphology of the product was analyzed. To the best of our knowledge, no studies have yet produced and investigated the aqueous solubility of mixed surfactant-based icariside II whey protein complexes (S-ICS-WPC).
Elucidation of technological, functional, sensory properties and aroma profiles of gluten-free breads enriched with lentil flour
Authors: Öncel Başak , Özer Mehmet Sertaç 
Published: January 2025

Abstract
This study aims at producing gluten-free bread (GFB) utilizing lentil flour (LF) that offers improved nutritional, textural, and sensory properties suitable for celiac patients. For this purpose, the control breads were modified by replacing starch with 10%, 20%, and 30% LF. The control group breads were produced by adding 4% xanthan to the mixture containing corn starch (70%) and gluten-free wheat starch (30%). The physicochemical properties, color, texture, bioactive properties, aroma composition, and sensory properties of the samples were examined. LF addition to the GFB formulation increased the specific volume and hardness of the samples, and the usage of 10% LF enhanced the chewiness of the bread (p < 0.05). The total amount of dietary fiber (TDL) in the bread samples ranged from 1.31 to 4.88 g/100 g. The total phenolic compound (TPC) content was measured as 0.33–0.75 mg GAE/100 g. The total antioxidant capacity (AA) varied from 0.05 to 2.91 µmol Trolox/100 g. Particularly, the bread samples with 30% LF demonstrated the highest values for these parameters. A total of 30 aroma compounds were identified in the samples, with the predominant component found during the aroma analysis being alcohol. The sensory evaluation conducted by the panelists indicated that the GFB with 30% LF was the most favored sample deemed suitable for consumption. In conclusion, a functional, nutritious, and preferable GFB formulation has been developed.
Factors associated with metal constituents in indoor particulate matter in different communities in South Africa
Authors: Buthelezi Minenhle S. , Naidoo Rajen N. , Bissessur Ajay , Shezi Busisiwe , Jafta Nkosana 
Published: January 2025

AbstractMetal constituents in indoor particulate matter (PM) emitted by household materials and indoor activities present an environmental challenge globally. This study investigated the variation of metal constituent concentrations in indoor PM collected from different communities and the association of metals with household characteristics and indoor occupant activities. PM2.5 and PM10 samples collected on Teflon filters during the field studies in the south and north Durban and Highveld region of South Africa were analysed for metal constituents by digesting in nitric acid and hydrochloric acid solution (aqua regia). These samples were analysed for metals using inductively coupled plasma-optical emission spectrometry (ICP-OES). Standardised interviews and structured household walkthrough assessments that were conducted provided additional covariates. Multivariate linear regression models were developed using factors from the factor analysis, and variables identified in the bivariate analysis. The decreasing order of metal content in PM2.5 was as follows: Fe > Cr > Cu > Mn > Al > Hg > Zn > As > Cd > Pb, whereas in PM10 the metal content had the following decreasing order: Fe > Al > As > Cu > Cr > Hg > Zn > Cd > Mn > Pb. Metal concentrations (Cd, Fe, Mn, and Pb) in PM2.5 varied significantly in different geographical locations. Household characteristics including higher household age, presence of a ceiling, and cemented floor type were significantly associated with increased Cr, Fe, and Hg in indoor PM2.5, respectively (p < 0.05). The association of metallic components in indoor PM with household characteristics provides an opportunity to raise issues of deteriorated old households to local authorities and policymakers who need to implement strategies to replace old building materials releasing metal-rich particles.
Addressing Factors that Impact Sexual Well-Being and Intimacy in IBD Patients
Authors: Elias Samantha , Nandi Neilanjan , Fourie Simona , Grover Lorraine , Newman Kira L. 
Published: January 2025

Abstract

Purpose of Review
This review details the pathophysiologic mechanisms from medical, surgical to psychosocial factors that illustrate how and why sexual health and intimacy are impacted in IBD.

Recent Findings
Recent clinical surveys of practicing gastroenterologists document that clinicians should routinely address sexual health when addressing patient reported outcomes but very few actually make direct inquiry or suggest management into this important aspect of human life. Example ‘patter’ are suggested to clinicians to demonstrate how to introduce the subject of sexual intimacy and well-being and engender patient trust on this sensitive topic. Once specific symptomatology are elicited, then a review follows on how referral to a cadre of available multidisciplinary specialists can help directly manage the patient’s concerns. Specific emphasis on addressing the sexual health in ostomate and sexual and gender minority populations is focused upon as well.

Summary
Overall, this in depth review highlights a practical clinical approach to understanding how to address sexual wellbeing and human intimacy in IBD patients.
Pulsed Electric Field Assisted Combined Freezing of Carrot Tissue: Preliminary Vacuum Freezing Followed by Supplementary Conventional Freezing
Authors: Huang Yuqi , Bals Olivier , Lebovka Nikolai , Vorobiev Eugène 
Published: January 2025

AbstractPulsed electric field (PEF) assisted combined mode of freezing with the preliminary vacuum freezing (VF) down to − 6 °C followed by conventional freezing (CF) in the freezer at − 20 °C has been studied. The fresh carrot tissue was electroporated to different levels of cell disintegration index Z = 0–0.9 (E = 0–400 V/cm, tPEF = 0–1 s). It was demonstrated that PEF significantly accelerated the kinetics of CF and impacted the texture, moisture losses, and microstructure of thawed carrots. For example, at a high disintegration index (Z = 0.9), the total freezing time was shortened by ≈1.21 times for the CF procedure and by ≈1.57 times for the combined VF + CF procedure. The softening of textures of carrots was observed; however, for both CF and VF + CF procedures, they were comparable. Application of both CF and VF + CF procedures resulted in the increase of the size of pores inside the carrot tissues. However, the water losses for the combined VF + CF protocol were significantly smaller than those for the CF protocol.