bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety and efficacy of low-energy small incision lenticule extraction for the correction of myopia and myopic astigmatism: A retrospective analysis
Authors: Varman N V Arulmozhi , Varman Aadithreya , Balakumar Dinesh 
Published: February 2023

Purpose:
To determine the safety and efficacy of low-energy settings in small incision lenticule extraction (SMILE) for correcting myopia and myopic astigmatism.

Methods:
We included patients aged ≥18 years with the myopia of −0.5 to −10 D and myopic astigmatism of −0.5 to −5 Dcyl in this retrospective case series performed at a private eye hospital in South India. All patients had preoperative best-corrected visual acuity of LogMar 0.0 ± 0, with stable refraction for 1 year and normal corneal topography. Ocular surface disease and other pathology cases were excluded. The repetition rate of the laser was 500 kHz, and the pulse energy was 110 nJ. The lenticule diameter was set at 6.5 mm, cap diameter was 7.20 mm, and intended cap thickness was 110–130 μ. The spot distance was 4.5 μm. All patients were evaluated immediately postoperation and on postoperative days 1, 8, and 30.

Results:
Overall, 541 eyes were included. The mean patient age was 25.03 ± 4.1 years. The mean spherical error was -3.76 ± 1.84 Ds. The mean cylinder was -1.24 ± 0.91. The mean spherical equivalent of refraction was −4.22 ±1.94 D. The logMAR on postoperative day 1 was 0.0 ± 0. The mean spherical equivalent at 1 month was 0.28 ± 1.06 D. There was no loss of Snellen’s lines after the procedure. The mean spherical equivalent of refraction to the target was 95% within ± 0.50 D. The postoperative astigmatism was within 0.5 Dycl. No intraoperative complications of SMILE including retained lenticule fragments, tears of incision, or improper dissection occurred.

Conclusion:
Low-energy settings in SMILE are safe and effective in correcting myopia and myopic astigmatism including high cylinders (>3 Dcyl).
Perception of college-going girls towards corneal donation in North India: A latent class analysis study
Authors: Gupta Parul Chawla , Rana Minakshi , Kumar-M Praveen , Agarwal Aniruddha , Duggal Mona , Sharma Raman , Jugran Deepak , Bhargava Nisha , Kaushal Vipin , Ram Jagat 
Published: February 2023

Purpose:
To assess the perception of college-going girls toward corneal donation in Northern India.

Methods:
An online survey with a pre-structured, pre-validated questionnaire was conducted on 1721 college-going girls in Northern India. The knowledge and attitude scores were regressed, and latent class analysis was carried out.

Results:
The average of scores for all participants was computed individually for the knowledge questions and the attitude questions, and based on this score, total participants were divided into two groups: Better corneal donation behaviors (BCDB) and poor corneal donation behaviors. The binomial logistic regression model of knowledge domain for predicting BCDB, age of the participant, their awareness about corneal donation, and willingness to discuss eye donation among family members were found significant. Similarly, for the attitude domain, awareness about corneal donation, knowledge about hours within which ideal eye donation needs to be undertaken, and knowledge about eye donation during coronavirus disease 2019 (COVID-19) pandemic were found to be significant. Latent class analysis identified one subset of participants having poorer knowledge and attitude scores and that they were more from a rural background, were having more than first order as birth order, were belonging to SC/ST classes, had illiterate or secondary education of father and mother, and were living in rented houses.

Conclusion:
The findings of the study significantly contribute to devising a mechanism to improve knowledge and influencing the attitude about eye donation among the youth, especially young women, who can act as counselors and motivators for the masses as well as their own families, in the generations to come.
Long-term retinal changes after strabismus surgery, suspected signs of past scleral perforations
Authors: Goldberg Hila , Blum Sharon , Palevski Dahlia , Cohen Gal , Armarnik Sharon , Wygnanski-Jaffe Tamara , Kinori Michael 
Published: February 2023

Purpose:
Scleral perforation during strabismus surgery is considered a rare complication that usually results in no significant consequences. The true rate of such occurrences is difficult to evaluate due to the young age of most patients and the occult nature of most events. This study aimed to evaluate long-term retinal changes under the suture areas in patients post-strabismus surgery as presumed signs indicating past undiscovered scleral perforations.

Methods:
The study population consisted of patients with a follow-up of at least 10 years post-strabismus surgery at the [redacted for review] Eye Institute and with no known retinal conditions as well as with wide fundus visibility. We performed slit-lamp retinal periphery examinations in search of retinal scars or changes at the suture sites.

Results:
Seventy-one eyes from 43 patients were examined. The mean age (±standard deviation [SD]) at the time of examination was 27 years (±14), and the mean number of strabismus surgeries per patient was 1.8. Three of the examined eyes showed retinal changes at the suture sites, yielding an overall incidence rate of suspected perforation/penetration of 4.2% per eye and 3.6% per strabismus surgery. These three patients were all asymptomatic.

Conclusion:
Scleral perforations during strabismus surgeries could remain unnoticed since a comprehensive exam of the retinal periphery is challenging in young children, especially during the postoperative period. While retinal changes caused by inadvertent scleral perforations appear to have no clinical sequelae in a time frame of 10 years, such changes should be noted for future fundoscopic examinations.
Determinants of Eye Disorders in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus in a Tertiary Hospital in Northern Nigeria
Authors: Muhammad Rilwan C. , Abdullahi Maryam H. , Oladigbolu Kehinde K. , Umar Abdul Aziz 
Published: February 2023

Objectives:
To investigate the determinants of eye disorders in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in a Tertiary Hospital in Northern Nigeria.

Methods:
This hospital-based study was conducted among patients with RA and SLE. Information was obtained on patients’ socio-demographics, type of rheumatic disease, disease duration, activity, and prescribed medications. RAPID 3 was used among both RA and SLE patients to measure and classify disease activity as: >12 = high; 6.1–12 = moderate; 3.1–6 = low; <3= remission. Each patient had detailed ocular examination. Statistical significance was set at P < 0.05.

Results:
The female:male ratio was 4.3:1 for RA and all SLE patients were females. Eye disorders were present in 42% of all patients, the most common being dry eyes (38%), refractive errors (18%), and cataracts (16%). The least findings were corneal opacities (2%) and lateral rectus palsy (2%). Mean duration of disease in years was significantly higher among RA patient that had eye disorders (7.23 ± 3.44) than those without (2.23 ± 1.23) (P < 0.001). It was also higher among SLE patients with eye disorders (6.73 ± 3.93) than those without (2.13 ± 1.06) (P < 0.001). Most RA patients with eye disorders had moderate [21 (28%)] to severe [8 (11%)] disease activity whereas majority of patients without eye disorders had low activity [16 (22%)] and near remission [26 (35%)] (P < 0.001). Most SLE patients with eye disorders had moderate [9 (35%)] to severe [1 (4%)] disease activity whereas majority of patients without eye disorders had low activity [3 (12%)] and near remission [12 (46%)].

Conclusion:
Eye disorders are common among RA and SLE patients, and are influenced by longer disease duration, higher disease activity, and older age. Gender and drug therapy were not found to influence the presence of eye disorders. Eye examination should be done on all RA and SLE patients at regular intervals.
Urinary coproporphyrins as a diagnostic biomarker of Dubin-Johnson syndrome in neonates: A diagnostic pathway is proposed
Authors: Al-Hussaini Abdulrahman , Asery Ali , Alharbi Omar 
Published: February 2023

Background:
Dubin-Johnson syndrome (DJS) presents during the neonatal period with a phenotype that overlaps with a broad list of causes of neonatal cholestasis (NC), which makes the identification of DJS challenging for clinicians. We conducted a case-controlled study to investigate the utility of urinary coproporphyrins (UCP) I% as a potential diagnostic biomarker.

Methods:
We reviewed our database of 533 cases of NC and identified 28 neonates with disease-causing variants in ATP-binding cassette-subfamily C member 2 (ABCC2) gene “Cases” (Study period 2008–2019). Another 20 neonates with cholestasis due to non-DJS diagnoses were included as “controls.” Both groups underwent UCP analysis to measure CP isomer I percentage (%).

Results:
Serum alanine aminotransferase (ALT) levels were within the normal range in 26 patients (92%) and mildly elevated in 2 patients. ALT levels were significantly lower in neonates with DJS than in NC from other causes (P < 0.001). The use of normal serum ALT levels to predict DJS among neonates with cholestasis had a sensitivity of 93%, specificity 90%, positive predictive value (PPV) 34%, and negative predictive value (NPV) 99.5%. The median UCPI% was significantly higher in DJS patients [88%, interquartile range (IQR) 1–IQR3, 84.2%–92.7%] than in NC from other causes [67%, (IQR1–IQR3, 61%–71.5%; Confidence interval 0.18–0.28; P < 0.001)]. The use of UCPI% >80% to predict DJS had a sensitivity, specificity, PPV, and NPV of 100%.

Conclusion:
Based on the results from our study, we propose sequencing of the ABCC2 gene in neonates with normal ALT, presence of cholestasis and UCP1% >80%.
El artículo, un género entre la opinión y la actualidad
Authors: Yanes Mesa Rafael 
Published: February 2023

El artículo es un género periodístico de opinión que refleja la interpretación que su autor hace sobre asuntos de la actualidad informativa. Se trata de un texto en el que se interpretan las noticias más recientes, aspecto que lo diferencia de un artículo literario. Su estructura goza de absoluta libertad, por lo que algunos investigadores afirman que existen tantos tipos de artículos como autores. Sin embargo, podemos distinguir cuatro modalidades de este género periodístico.
La columna es un modelo de artículo en el que su autor dispone de total libertad para emitir sus juicios sobre los asuntos que considere oportunos, y lo hace en un periódico donde cuenta con una ubicación, una extensión y una periodicidad fijas.
El editorial es una modalidad del artículo por medio del que se manifiesta públicamente la empresa propietaria de un periódico sobre asuntos de trascendencia social o política.
El artículo firmado es un artículo cuyo autor no es un periodista integrante de la plantilla laboral del periódico, quien escribe de forma esporádica y con absoluta libertad expresiva un texto sin una ubicación ni extensión fija.
El obituario es el artículo en el que se hace una semblanza con detalles íntimos y datos profesionales de un personaje con motivo de su fallecimiento.
Concepções de Saúde na formação de professores de Educação Física
Authors: MARÇAL GROSSI MONIQUE , Ramos Paula 
Published: February 2023

No presente estudo, partimos da compreensão de que o professor de educação física está na interface entre as áreas de educação e saúde e que, portanto, a discussão sobre os temas “saúde” e “promoção da saúde” são fundamentais para sua formação e prática docentes. Buscamos compreender quais as concepções de saúde presentes na formação em Educação Física dos cursos de Licenciatura em Educação Física. Para tanto o objetivo geral dessa pesquisa consiste em analisar as concepções de saúde presentes na formação em Educação Física dos cursos de licenciatura da Universidade Federal do Rio de Janeiro – (UFRJ) e Universidade Federal Fluminense (UFF). Se trata de um estudo qualitativo com base na análise do Projeto Curricular de Curso de dois cursos de licenciatura em EF. A partir dessa análise identificamos que nos aspectos conceituais, os dois projetos existem elementos norteadores que visam a formação de um professor crítico, capaz de entender questões sociais e transformador dessa realidade. Tais princípios se articulam com a perspectiva da Promoção da Saúde em uma abordagem da saúde como valor social. No entanto ao materializar tal discussão na matriz curricular, as disciplinas que abordariam a saúde se localizam no eixo biológico. Por fim, é importante incorporar na formação de professores a compreensão do processo saúde-doença como um valor social assim como o debate crítico sobre promoção da saúde.
Palavras- chave: Formação Docente. Saúde. Educação Física.
PENGARUH KUALITAS SDM DAN KOMPETENSI TERHADAP KINERJA PEGAWAI PADA DINAS PERTANIAN DAN PANGAN KABUPATEN PIDIE JAYA
Authors: Syamsul Akmal , Amiruddin Amiruddin , Nikar Mardia 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui “Pengaruh Kualitas SDM dan Kompetensi Terhadap Kinerja Pegawai Pada Kantor Dinas Pertanian dan Pangan Kabupaten Pidie Jaya”. Populasi dalam penelitian ini adalah seluruh pegawai di Dinas Pertanian dan Pangan Kabupaten Pidie Jaya yang berjumlah 126 orang di Dinas Pertanian dan Pangan Kabupaten Pidie Jaya dengan sampel 82 orang.Data hasil penelitian dianalisis dengan peralatan statistik sederhana antara lain distribusi frkuensi, persentase dan rata-rata. Untuk mengukur kehandalan variabel dalam kuesioner dengan analisis Cronbach Alpha pada taraf signifikansi 0,5. Untuk membuktikan hipotesis lebih lanjut digunakan peralatan Pearson’ Correlation, Linear Regression, dan t-test. Hasil penelitian bahwa persamaan regresi linear berganda dapat dijelaskan nilai konstanta sebesar 4,414 artinya kinerja pegawai Dinas Pertanian dan Pangan Kabuapten Pidie Jaya tanpa pengaruh variabel. Nilai koefisien regresi kompetensi sebesar 0,353 diartikan bahwa setiap 1% kenaikan kualitas SDM (X1) akan meningkatkan kinerja pegawai Dinas Pertanian dan Pangan Kabupaten Pidie Jaya. Nilai koefisien regresi kompetensi sebesar 0,466 diartikan bahwa kompetensi (X2) akan meningkatkan kinerja pegawai Dinas Pertanian dan Pangan Kabupaten Pidie Jaya mempunyai pengaruh yang dominan terhadap kinerja pegawai Dinas Pertanian dan Pangan Kabupaten Pidie Jaya. Hubungan variabel dependen dan independen yaitu variabel kualitas SDM (X1) dan kompetensi (X2) terhadap kinerja (Y) pegawai Dinas Pertanian dan Pangan Kabupaten Pidie Jaya dengan koefisien korelasi sebesar 0,774 ini berarti hubungan tersebut sangat kuat. Koefisien determinasi variabel kualitas SDM (X1) dan kompetensi (X2) sebesar 59,8% ini berarti keduanya berpengaruh secara signifikan terhadap kinerja pegawai Pertanian dan Pangan Kabupaten Pidie Jaya dan sebesar 40,2% yang dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini. Secara parsial variabel kualitas SDM (X1) diperoleh thitung 4,062 ttabel 1,664 dan variabel kompetensi (X2) diperoleh thitung 4,922 ttabel 1,664 sehingga Hipotesis Nol (Ho) ditolak dan Hipotesis Alternatif (Ha) diterima. Secara simultan variable kualitas SDM (X1) dan variable kompetensi (X2) diperoleh nilai Fhitung 58,858 Ftabel 2,72 sehingga Hipotesis Nol (Ho) ditolak dan Hipotesis Alternatif (Ha) diterima
Conformity Test of Human Chorionic Gonadotropin (HCG) Test Results Using Immunochromatographic Method between Various Brands
Authors: Ilu Osni , Torajasa Achmar  , Srikitnurkamiden  
Published: February 2023

Human Chorionic Gonadotropin (HCG) is a hormone produced by the placental tissue in early pregnancy. This hormone is excreted in the urine or when there is an abnormal proliferation of the chorionic epithelial tissue, such as moles or choriocarcinoma. The problem formulation in this study is that there is a match between the results of the HCG examination using the immunochromatographic method on three different brands at the Kabila Health Center, Bone Bolango District. This study aims to determine the suitability of the results of the HCG examination with the Immunochromatographic Method on three different brands.
The method in this study used a quantitative approach. The type of data used was primary data in the form of research results and secondary data in the form of data from literature, books and documents. The sampling technique in this study used an accidental sampling technique with a sample of 30 people.
From the research that has been conducted on 30 urine samples of pregnant women using three brands of Human Chorionic Gonadotropin (HCG) kits, namely: 1) one med test. 2) medical sterile test. 3) the accurate strip; shows the results that there was no significant difference to the results of the suitability test of HCG using these three brands.
DESCRIPTION OF ELECTROLYTE LEVELS IN PATIENTS WITH KIDNEY FAILURE IN TOTO KABILA HOSPITAL, BOLANGO REGENCY, GORONTALO PROVINCE
Authors: Bilondatu Sri Yuliana , Arwati Niluh , Rusdin  
Published: February 2023

This study aims to determine electrolyte levels in patients with kidney failure.
Research methods using a descriptive quantitative approach. Descriptive is an observation whose purpose is to describe by exposing one of the symptoms, conditions and circumstances experienced
sampling technique in this study used the accidental sampling technique , a collection of samples by accidental means in taking cases and respondents who happened to be available or available in one of the places based on the context of observation. The reasons for using accidental sampling in this study because the population of kidney failure patients was not fixed, some had recovered, some had died and some were irregular in treatment or in carrying out hemodialysis (dialysis) so that , with a total sample of 20 people .
Research results which was carried out at Toto Kabila Hospital, Bone Bolango Regency, showed that out of 20 patients with kidney failure, there were 17 people or 85% whose electrolyte levels were abnormal, while those whose electrolytes were normal were 3 people or 15%.
DESCRIPTION OF RHEUMATOID FACTOR IN THE ELDERLY IN THE WORKING AREA OF THE NORTH TOTO HEALTH CENTER
Authors: Domut Nurmila , Malaha Adnan , Engelen Adnan 
Published: February 2023

Rheumatoid factor (RF) is an immunoglobulin that reacts with the IgG molecule as its name indicates, RF is primarily used for the examination and monitoring of rheumatoid arthritis. Rheumatoid arthritis (rheumatism) is a disease where the immune system fails to distinguish its own tissue from foreign substances. The aim of the study was to determine the results of rheumatoid factor in the elderly in the working area of ​​the Toto Utara Public Health Center, Bone Bolango Regency, Gorontalo Province.
The method used in this study is a descriptive qualitative approach, with primary data sources in the form of examination resultsrheumatoid factorin the serum of patients with rheumatoid arthritis in a number of 15 samplesobtained using the sampling technique that ispurposive sampling.
The results of the examination of rheumatoid factor using serum obtained inOf the 15 samples of rheumatoid arthritis sufferers aged 60 to 63 years who were positive by examining the agglutination test using the glory diagnostic kit test tool, on the results of laboratory tests, there were 4 samples (26.6%) positive for rheumatoid factor, namely 3 were female (20%) and 1 was male. male sex (6.6%).
Triggering and relieving factors of migraine among university students: A cross-sectional study in Lebanon
Authors: Mosleh Reva , Hatem Georges , Navasardyan Nare , Ajrouche Roula , Zein Salam , Awada Sanaa 
Published: February 2023

Introduction
Migraine is common among university students and can directly affect their daily activities and learning since students with migraine have difficulties attending classes and missed more school days than other students.
Objectives
This study aimed to identify triggering factors of migraine along with factors that relieve headaches associated with migraine episodes among university students.
Methods
An observational cross-sectional study targeted students from different faculties of the public university campus in Lebanon using a survey for data collection.
Results
Feeling hungry (65.9%), fasting (50.7%), and coffee deprivation (22.7%) were the most commonly reported dietary factors inducing headaches among university students. In comparison, climate changes (77.1%), noise and high volumes (73.9%), and hot weather (60.2%) were the most common environmental triggers. Among the psychological factors, anxiety (53.4%) and crying (47.3%) were highly reported and were significantly higher among women. Fatigue (63.2%), studying for exams (59.5%), and neck pain (46.8%) were the most common physical activity-reported factors. Lack of sleep (72%) and changes in sleeping hours (42.7%) were the primarily reported sleeping habits that can trigger headaches, with no statistically significant differences between men and women. Sleeping (66.3%), relaxing (53.4%), avoiding migraine’s trigger factors (42.9%), and having a warm bath (38.5%) were the most reported relieving factors of headache among students. No statistically significant association was noted between any of the factors and the sex of the participants.
Conclusion
The triggering and relieving factors of migraine were comparable between men and women. Some triggering factors such as crying, anxiety, and fatigue were found significant among women, while driving was a higher migraine trigger among men. Lifestyle interventions may provide clues on effective relieving strategies and yield the establishment of different medical services and university programs.
Analisis pendapatan usaha kopi tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah
Authors: Sari Intan 
Published: February 2023

Penelitian ini dilakukan pada Usaha Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah. Tujuan penelitian untuk mengetahui pendapatan Usaha Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah dan menganalisis Kelayakan Usaha Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah. Berdasarkan hasil penelitian pada usaha Bubuk Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah diperoleh bahwa rata-rata penerimaan pada usaha produksi Bubuk Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah adalah Rp. 450.000.000,00/tahun. Sementara keuntungan yang diperoleh sebesar Rp. 329.853.750/tahun. Perhitungan B/C rasio adalah 2,75, atau 2,75 > 0, Hal ini menunjukkan bahwa usaha produksi Bubuk Kopi Tubruk Gayo di Desa Conto Kecamatan Timang Gajah Kabupaten Bener Meriah dapat dikatakan menguntungkan dan layak dijalankan.
Kata kunci : Analisis, Pendapatan, Kopi Tubruk