bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delayed Freshwater Export from a Greenland Tidewater Glacial Fjord
Authors: Sanchez Robert , Slater Donald , Straneo Fiammetta 
Published: February 2023

Abstract
Freshwater from the Greenland Ice Sheet is routed to the ocean through narrow fjords along the coastline where it impacts ecosystems both within the fjord and on the continental shelf, regional circulation, and potentially the global overturning circulation. However, the timing of freshwater export is sensitive to the residence time of waters within glacial fjords. Here, we present evidence of seasonal freshwater storage in a tidewater glacial fjord using hydrographic and velocity data collected over 10 days during the summers of 2012 and 2013 in Saqqarleq (SQ), a midsize fjord in west Greenland. The data revealed a rapid freshening trend of −0.05 ± 0.01 and −0.04 ± 0.01 g kg−1 day−1 in 2012 and 2013, respectively, within the intermediate layer of the fjord (15–100 m) less than 2.5 km from the glacier terminus. The freshening trend is driven, in part, by the downward mixing of outflowing glacially modified water near the surface and increasingly stratifies the fjord from the surface downward over the summer melt season. We construct a box model that recreates the first-order dynamics of the fjord and describes freshwater storage as a balance between friction and density-driven exchange outside the fjord. The model can be used to diagnose the time scale for this balance to be reached, and for SQ we find a month lag between subglacial meltwater discharge and net freshwater export. These results indicate a fjord-induced delay in freshwater export to the ocean that should be represented in large-scale models seeking to understand the impact of Greenland freshwater on the regional climate system.
Delayed Tracheostomy After Cervical Fixation is Not Associated With Improved Outcomes: A Trauma Quality Improvement Program Analysis
Authors: Kelly Emma M. , Fleming Andrew M. , Lenart Emily K. , Howley Isaac W. , Fischer Peter E. , Kerwin Andrew J. , Filiberto Dina M. , Byerly Saskya 
Published: February 2023

Background Patients with unstable cervical spine (C-spine) fractures are at a significant risk of respiratory failure. There is no consensus on the optimal timing of tracheostomy in the setting of recent operative cervical fixation (OCF). This study evaluated the impact of tracheostomy timing on surgical site infections (SSIs) in patients undergoing OCF and tracheostomy. Methods Trauma Quality Improvement Program (TQIP) was used to identify patients with isolated cervical spine injuries who underwent OCF and tracheostomy between 2017 and 2019. Early tracheostomy (<7 days from OCF) was compared with delayed tracheostomy (≥7 days from OCF). Logistic regressions identified variables associated with SSI, morbidity, and mortality. Pearson correlations evaluated time to tracheostomy and length of stay (LOS). Results Of 1438 patients included, 20 had SSI (1.4%). There was no difference in SSI between early vs delayed tracheostomy (1.6% vs 1.2%, P = .5077). Delayed tracheostomy was associated with increased ICU LOS (23.0 vs 17.0 days, P < .0001), ventilator days (19.0 vs 15.0, P < .0001), and hospital LOS (29.0 vs 22.0 days, P < .0001). Increased ICU LOS was associated with SSI (OR 1.017; CI 0.999-1.032; P = .0273). Increased time to tracheostomy was associated with increased morbidity (OR 1.003; CI 1.002-1.004; P < .0001) on multivariable analysis. Time from OCF to tracheostomy correlated with ICU LOS (r (1354) = .35, P < .0001), ventilator days (r (1312) = .25, P < .0001), and hospital LOS (r (1355) = .25, P < .0001). Conclusion In this TQIP study, delayed tracheostomy after OCF was associated with longer ICU LOS and increased morbidity without increased SSI. This supports the TQIP best practice guidelines recommending that tracheostomy should not be delayed for concern of increased SSI risk.
Outcomes of Small Bowel Obstructions by Admitting Specialty and Hospital Type
Authors: Sternick Molly , Licata Andrew , Britt Rebecca 
Published: February 2023

Background Small bowel obstructions (SBOs) account for a significant burden on the health care system. Should the ongoing trend of regionalizing medicine extend to these patients? We investigated if there is a benefit to admitting SBOs to larger teaching hospitals and to surgical services. Methods We performed a retrospective chart review of 505 patients admitted to a Sentara Facility between 2012 and 2019 with a diagnosis of SBO. Patients between the ages of 18 and 89 were included. Patients were excluded if they required emergent operation. Outcomes were evaluated based on patient’s admission either to a teaching or community hospital as well as the admitting service’s specialty. Results Of 505 patients admitted with a SBO, 351 (69.5%) were admitted to a teaching hospital. 392 (77.6%) patients were admitted to a surgical service. The average length of stay (LOS) (4 vs 7 days, P < .0001) and cost ($18,069.79 vs $26,458.20, P < .0001) were lower at teaching hospitals. The same trends in LOS (4 vs 7 days, P < .0001) and cost ($18,265.10 vs $29 944.82, P < .0001) were seen with surgical services. The 30-day readmission rate was higher in teaching hospitals (18.2% vs 11%, P = .0429), and no difference was seen in operative rate or mortality. Discussion These data would suggest that there is a benefit to admitting SBO patients to larger teaching hospitals and to surgical services with regard to LOS and cost, suggesting that these patients might benefit from treatment at centers with emergency general surgery (EGS) Services.
The role of spirituality and religiosity on the suicidal ideation of medical students
Authors: Vitorino Luciano Magalhães , Lucchetti Giancarlo , Saba Isabella Fidelis , Nalon Júlia Maria Maluf Caldas Anghietti , de Faria Rodolfo Souza , Trzesniak Clarissa 
Published: February 2023

Background: There is solid evidence that spirituality and religiousness may reduce the suicidal ideation of individuals. However, studies are scarce on medical students. Aims: To investigate the relationship between spirituality, religiousness, and suicidal ideation among Brazilian medical students. Methods: This is a cross-sectional study including Brazilian medical students. Sociodemographic and health variables, suicidal ideation (item 9 of the Beck Depression Inventory – BDI), spiritual and religious Coping (Brief SRC), religiousness (Duke Religion Index), spiritual well-being – Meaning, Peace and Faith (FACIT SP-12), and depressive (PHQ-9) and anxiety (GAD-7) symptoms were assessed. Results: A total of 353 medical students were included, 62.0% presented significant depressive symptoms, 44.2% presented significant anxiety symptoms, and 14.2% presented suicidal ideation. In the adjusted Logistic Regression models, meaning ( OR = 0.90, p = .035) and faith ( OR = 0.91, p = .042) were associated with lower suicidal ideation, while negative spiritual and religious coping was associated with greater suicidal ideation ( OR = 1.08; p = .006). Conclusion: There was a high prevalence of suicidal ideation among Brazilian medical students. Spirituality and religiousness were associated with suicidal ideation in two different directions. These findings could help educators and health professionals to understand suicidal ideation among medical students, helping in the development of preventive strategies to mitigate such problem.
Guts, Resilience, Integrity, and Tenacity (GRIT) Among Mid Adolescent School Students in a District of South India: A Cross-Sectional Study
Authors: Britto Dharmaraj Rock , Rizvana Abdul Malik Shagirunisha , George Neethu , Subramaniyan Dharshini , Narayanan Dhayanitha , Mani Divya Keerthana Rameshwari , Annadurai Elakiya , Prakas Enitta Josephine 
Published: February 2023

Background: Guts, Resilience, Integrity, and Tenacity (GRIT) is an optimistic character that mixes passion and dedication. It is a driver of achievement and success, independent of and beyond what intelligence and talent contribute. The study aimed to assess GRIT and factors influencing it among mid-adolescent school students (13–18 years) in the Perambalur district, Tamilnadu, India. Methods: A cross-sectional study was conducted among mid-adolescent school students. We used a self-reported questionnaire to collect the data on sociodemographic characteristics and parents’ details and the standard eight-item GRIT questions. Analysis was done with the total and subscale scores. Results: Among the 1663 participants, 966 (58.1%) were males. The mean (SD) age was 15.6 (1.19) years. The mean GRIT score was 26.65 (4.12). Most students (755) showed medium (45.4%) GRIT scores. The age factor had a weak negative correlation with GRIT ( r = −0.052, p = 0.033) and females had higher scores ( t = 9.13, p = 0.002). Perseverance of effort was significantly more in those from a rural background ( t = 1.9, p = 0.012), while consistency of interest was more in those from urban background ( t = 0.63, p = 0.03). Conclusion: Most students had average or medium GRIT scores, with higher GRIT among females. The concept of GRIT should be properly addressed among children during their school years in order to inspire them to dream with passion and perseverance.
Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: A protocol for a randomised controlled study (ProMPT2)
Authors: Heys Rachael , Angelini Gianni D , Joyce Katherine , Smartt Helena , Culliford Lucy , Maishman Rachel , de Jesus Samantha E , Emanueli Costanza , Suleiman M-Saadeh , Punjabi Prakash , Rogers Chris A , Gibbison Ben 
Published: February 2023

Introduction Cardiac surgery with cardiopulmonary bypass and cardioplegic arrest is known to be responsible for ischaemia and reperfusion organ injury. In a previous study, ProMPT, in patients undergoing coronary artery bypass or aortic valve surgery we demonstrated improved cardiac protection when supplementing the cardioplegia solution with propofol (6 mcg/ml). The aim of the ProMPT2 study is to determine whether higher levels of propofol added to the cardioplegia could result in increased cardiac protection. Methods and Analysis The ProMPT2 study is a multi-centre, parallel, three-group, randomised controlled trial in adults undergoing non-emergency isolated coronary artery bypass graft surgery with cardiopulmonary bypass. A total of 240 patients will be randomised in a 1:1:1 ratio to receive either cardioplegia supplementation with high dose of propofol (12 mcg/ml), low dose of propofol (6 mcg/ml) or placebo (saline). The primary outcome is myocardial injury, assessed by serial measurements of myocardial troponin T up to 48 hours after surgery. Secondary outcomes include biomarkers of renal function (creatinine) and metabolism (lactate). Ethics and Dissemination The trial received research ethics approval from South Central – Berkshire B Research Ethics Committee and Medicines and Healthcare products Regulatory Agency in September 2018. Any findings will be shared though peer-reviewed publications and presented at international and national meetings. Participants will be informed of results through patient organisations and newsletters. Trial Registration ISRCTN15255199. Registered in March 2019.
Psychometric properties of light touch-pressure somatosensory measures in adults with neurological disorders: A systematic review
Authors: Vora Isha , Kline Danielle K , McCauley Colleen A , Link Angela , Asiello Jessica D , Gaudino Shonali G , Reilly William J , Keilty Matthew S , Banks Russell E , Kimberley Teresa J 
Published: February 2023

Objectives To critically appraise the psychometric properties of light touch-pressure somatosensory assessments to provide guidance for tool selection for research or clinical purposes. Data sources MEDLINE, CINAHL, and PsycInfo were searched for research indexed from January 1990-November 2022. English language and human subject filters were applied. “Somatosensation”, “psychometric property”, and “nervous system-based health condition” search terms were combined. Grey literature and manual searches were conducted to ensure thoroughness. Review methods The reliability, construct validity, and/or measurement error of light touch-pressure assessments was reviewed in adult populations with neurological disorders. Reviewers individually extracted and managed data including patient demographics, assessment characteristics, statistical methods, and psychometric properties. Methodological quality of results was evaluated using an adapted version of the COnsensus-based Standards for the selection of health Measurement INstruments checklist. Results Thirty-three of 1938 articles were included for review. Fifteen light touch-pressure assessments demonstrated good or excellent reliability. Further, five of those 15 assessments achieved adequate validity and one of the 15 assessments achieved adequate measurement error. Over 80% of the summarized study ratings were determined to be of low or very low quality. Conclusion We recommend using electrical perceptual tests, the Semmes-Weinstein Monofilaments, the Graded and Redefined Assessment of Strength, Sensibility, and Prehension, and the Moving Touch Pressure Test given that they demonstrated good to excellent results in three psychometric properties. No other assessment achieved adequate ratings in more than two psychometric properties. This review highlights a fundamental need to develop sensory assessments that are reliable, valid, and sensitive to change.
COVID-19 Booster Vaccination Bellwethers: Factors Predictive of Older Adults’ Adoption of the Second Booster COVID-19 Vaccine in Israel: A Longitudinal Study
Authors: Ben-David Boaz M. , Keisari Shoshi , Regev Tali , Palgi Yuval 
Published: February 2023

Israel became the first country to offer the second COVID-19 booster vaccination. The study tested for the first time, the predictive role of booster-related sense of control (SOC_B), trust and vaccination hesitancy (VH) on adoption of the second-booster among older adults, 7 months later. Four hundred Israelis (≥60 years-old), eligible for the first booster, responded online, two weeks into the first booster campaign. They completed demographics, self-reports, and first booster vaccination status (early-adopters or not). Second booster vaccination status was collected for 280 eligible responders: early- and late-adopters, vaccinated four and 75 days into the second booster campaign, respectively, versus non-adopters. Multinomial logistic regression was conducted with pseudo R2 = .385. Higher SOC_B, and first booster early-adoption were predictive of second booster early-vs.-non-adoption, 1.934 [1.148–3.257], 4.861 [1.847–12.791]; and late-vs.-non-adoption, 2.031 [1.294–3.188], 2.092 [0.979–4.472]. Higher trust was only predictive of late-vs.-non-adoption (1.981 [1.03–3.81]), whereas VH was non-predictive. We suggest that older-adult bellwethers, second booster early-adopters, could be predicted by higher SOC_B, and first booster early-adoption, 7 months earlier.
Sesamoid View Weightbearing Radiography vs Weightbearing Computed Tomography in the Measurement of Metatarsal Pronation Angle
Authors: Siebert Matthew J. , Steadman Jesse N. , Saltzman Charles L. 
Published: February 2023

Background: First metatarsal pronation angle (MPA) is increasingly relevant in the management of hallux valgus and is assessed on weightbearing computed tomography (WBCT) and sesamoid-view weightbearing radiography (WBR). The purpose of this study is to compare MPA measured by WBCT against WBR to determine if any systematic discrepancy in MPA measurement exists between the 2 modalities. Methods: A total of 40 patients with 55 feet were included for study. MPA was measured in all patients by 2 independent readers on both WBCT and WBR with an appropriate washout period between measurement modalities. Mean MPA by WBCT and WBR were analyzed; interobserver reliability was calculated with an intraclass correlation coefficient (ICC) value. Results: Mean MPA as measured by WBCT was 3.7 ± 7.9 degrees (95% CI, 1.6-5.9; range −11.7 to 20.5). Mean MPA measured on WBR was 3.6 ± 8.4 degrees, (95% CI, 1.4-5.8; range −12.6 to 21.4). There was no difference in MPA as measured by WBCT compared to WBR ( P = .529). Interobserver reliability was excellent with an ICC of 0.994 for WBCT and 0.986 for WBR. Conclusion: Measurement of first MPA by WBCT and WBR was not significantly different. In our cohort of patients with and without forefoot pathology, we found that either sesamoid view weightbearing radiographs or weightbearing CT can be used reliably to measure first MPA and will generate similar values. Level of Evidence: Level IV, case series.
Near and Far Transfer Effects of Computerized Progressive Attention Training (CPAT) Versus Mindfulness Based Stress Reduction (MBSR) Practice Among Adults With ADHD
Authors: Stern Pnina , Kolodny Tamar , Tsafrir Shlomit , Cohen Galit , Shalev Lilach 
Published: February 2023

Objective: The present study evaluated the near (attention) and far (reading, ADHD symptoms, learning, and quality of life) transfer effects of a Computerized Progressive Attention Training (CPAT) versus Mindfulness Based Stress Reduction (MBSR) practice among adults with ADHD compared to a passive group. Method: Fifty-four adults participated in a non-fully randomized controlled trial. Participants in the intervention groups completed eight 2-hr weekly training sessions. Outcomes were assessed before, immediately after, and 4 months post-intervention, using objective tools: attention tests, eye-tracker, and subjective questionnaires. Results: Both interventions showed near-transfer to various attention functions. The CPAT produced far-transfer effects to reading, ADHD symptoms, and learning while the MBSR improved the self-perceived quality of life. At follow-up, all improvements except for ADHD symptoms were preserved in the CPAT group. The MBSR group showed mixed preservations. Conclusion: Both interventions have beneficial effects, however only the CPAT group exhibited improvements compared to the passive group.
The longitudinal relation between loneliness and perceived stress: A structural equation modelling analysis of 10,159 individuals
Authors: Laustsen Lisbeth M , Christiansen Julie , Maindal Helle T , Plana-Ripoll Oleguer , Lasgaard Mathias 
Published: February 2023

Aims: Prolonged loneliness and severe stress are increasingly recognised as public health concerns and considered risk factors for mental disorders, somatic illnesses and mortality. Loneliness and perceived stress also often co-occur; however, their longitudinal relation remains unclear. To the best of our knowledge, this is the first study aiming to investigate the longitudinal relation between loneliness and perceived stress independently of cross-sectional associations and time effects. Methods: Designed as a population-based cohort study with repeated measurements, the present study included individuals aged 16–80 years at baseline who participated in the Danish National Health Survey (‘How are you?’) in 2013 and 2017 ( N = 10,159; response rate = 50%). Structural equation modelling was used to examine associations between loneliness and perceived stress in the total sample and across age groups (i.e., 16–29, 30–64 and 65–80 years). Results: The models indicated bidirectional relations between loneliness and perceived stress. The standardized cross-lagged path from loneliness to perceived stress (β: 0.12, 95% confidence interval (CI) (0.08, 0.16), p < 0.001) and from perceived stress to loneliness (β: 0.12, 95% CI (0.07, 0.16), p < 0.001) both corresponded to small effect sizes in the total sample. Additionally, the results indicated strong cross-sectional associations, especially among adolescents and young adults (16–29 years), and high temporal stability, especially among the elderly (65–80 years). Conclusions: Loneliness and perceived stress mutually predict each other over time. The finding of both substantial bidirectional and cross-sectional associations demonstrates an interdependence between loneliness and perceived stress that may be relevant to consider in future interventions.
What Postoperative Nutritional Interventions Lead to Better Outcomes in Fragility Hip Fractures? A Systematic Review
Authors: Oberstar Jennifer S. , Bakker Caitlin J. , Sorich Megan , McCarthy Teresa 
Published: February 2023

Background Fragility hip fracture patients are often malnourished. Nutrition supplementation may help, but it is unclear if supplementation is impactful when considering outcomes. A systematic review of literature examining perioperative nutrition status for older adults experiencing a hip fracture was performed. Methods We searched Medline, CAB Abstracts and Embase (Ovid); Cochrane Library (Wiley); PubMed; Scopus; Global Index Medicus; Web of Science Core Collection; SPORTDiscus (EBSCO); and clinical trial registries ClinicalTrials.gov and WHO ICTRP from inception to April 2021, incorporating terminology related to nutritional interventions, fragility fractures, and postoperative outcomes. Two investigators reviewed citations for inclusion, extracted nutrition intervention criteria, and categorized hip fragility outcomes. Results Of 1792 citations, 90 articles underwent full-text screening, and 14 articles were included in the final sample. We identified nutritional interventions and 4 outcomes of interest. 8 studies (n = 649) demonstrated a mean difference of .78 days (CI .34-1.21) in length of stay (LOS) between the nutritional intervention and control groups. Rehabilitation ward stays were discussed in 2 studies demonstrating a non-statistically significant difference. 7 studies (n = 341) reported mortality rates; when pooled there was no statistically significant difference. 5 studies showed data for postoperative infections and 4 studies reported on postoperative urinary tract infections. Pooling of data found a statistically significant result (Relative Risk: .49 [.32, .75], P = .001) with low heterogeneity (I2 = 27%). 4 studies reported urinary tract infections (n = 140) in the intervention group and (n = 121) in the control group with a non-statistically significant result. Grip strength was only reported in two studies but pooling of the data was non-statistically significant. Conclusions This systematic review highlighted the lack of consensus regarding the type of nutrition interventions available and impact on outcomes of interest including mortality, length of stay, infections, and grip strength for fragility hip fractures in older adults.