bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unlikely intersections and the Chabauty–Kim method over number fields
Authors: Dogra Netan 
Published: May 2023

AbstractThe Chabauty–Kim method is a tool for finding the integral or rational points on varieties over number fields via certain transcendental p-adic analytic functions arising from certain Selmer schemes associated to the unipotent fundamental group of the variety. In this paper we establish several foundational results on the Chabauty–Kim method for curves over number fields. The two main ingredients in the proof of these results are an unlikely intersection result for zeroes of iterated integrals, and a careful analysis of the intersection of the Selmer scheme of the original curve with the unipotent Albanese variety of certain $${\mathbb {Q}}_p $$

Q
p

-subvarieties of the restriction of scalars of the curve. The main theorem also gives a partial answer to a question of Siksek on Chabauty’s method over number fields, and an explicit counterexample is given to the strong form of Siksek’s question.
Phenomenology and therapeutic potential of patient experiences during oral esketamine treatment for treatment-resistant depression: an interpretative phenomenological study
Authors: Breeksema Joost J. , Niemeijer Alistair , Kuin Bouwe , Veraart Jolien , Vermetten Eric , Kamphuis Jeanine , van den Brink Wim , Schoevers Robert 
Published: May 2023

Abstract
Background
Ketamine and its enantiomers are widely researched and increasingly used to treat mental disorders, especially treatment-resistant depression. The phenomenology of ketamine-induced experiences and their relation to its psychotherapeutic potential have not yet been systematically investigated.

Aims
To describe the phenomenology of patient experiences during oral esketamine treatment for treatment-resistant depression (TRD) and to explore the potential therapeutic relevance of these experiences.

Methods
In-depth interviews were conducted with 17 patients after a 6-week, twice-weekly ‘off label’ generic oral esketamine (0.5–3.0mg/kg) treatment program. Interviews explored participants’ perspectives, expectations, and experiences with oral esketamine treatment. Audio interviews were transcribed and analyzed using an Interpretative Phenomenological Analysis (IPA) framework.

Results
The effects of ketamine were highly variable, and psychological distress was common in most patients. Key themes included (a) perceptual effects (auditory, visual, proprioceptive), (b) detachment (from body, self, emotions, and the world), (c) stillness and openness, (d) mystical-type effects (transcendence, relativeness, spirituality), and (e) fear and anxiety. Key themes related to post-session reports included (a) feeling hungover and fatigued, and (b) lifting the blanket: neutralizing mood effects.

Conclusion
Patients reported several esketamine effects with psychotherapeutic potential, such as increased openness, detachment, an interruption of negativity, and mystical-type experiences. These experiences deserve to be explored further to enhance treatment outcomes in patients with TRD. Given the frequency and severity of the perceived distress, we identify a need for additional support in all stages of esketamine treatment.
The Impact of Surgeon Speciality Interest on Outcomes of Emergency Laparotomy in IBD
Authors: Bunce J. A. , Doleman B. , Lund J. N. , Tierney G. M. 
Published: May 2023

AbstractIntroductionEmergency laparotomy may be required in patients with inflammatory bowel disease (IBD). NELA is the largest prospectively maintained database of adult emergency laparotomies in England and Wales and includes clinical urgency of the cases. The impact of surgeon subspeciality on outcomes after emergency laparotomy for IBD is unclear. We have investigated this association, according to the degree of urgency in IBD emergency laparotomy, including the effect of minimally invasive surgery (MIS).MethodsAdults with IBD in the NELA database between 2013 and 2016 were included. Surgeon subspeciality was colorectal or non‐colorectal. Urgencies are ‘Immediate’, ‘2–6 h’, ‘6–18 h’ and ’18–24 h’. Logistic regression was used to investigate in‐patient mortality and post‐operative length of stay (LOS).ResultsThere was significantly reduced mortality and LOS in IBD patients who were operated on by a colorectal surgeon in the least urgent category of emergency laparotomies; Mortality adjusted OR 2.99 (CI 1.2–7.8) P = 0.025, LOS IRR 1.18 (CI 1.02–1.4) P = 0.025. This association was not seen in more urgent categories. Colorectal surgeons were more likely to use MIS, P < 0.001, and MIS was associated with decreased LOS in the least urgent cohort, P < 0.001, but not in the other urgencies.ConclusionsWe found improved outcomes in the least urgent cohort of IBD emergency laparotomies when operated on by a colorectal surgeon in comparison to a non‐colorectal general surgeon. In the most urgent cases, there was no benefit in the operation being performed by a colorectal surgeon. Further work on characterising IBD emergencies by urgency would be of value.
Practicable robust stochastic optimization under divergence measures with an application to equitable humanitarian response planning
Authors: Caunhye Aakil M. , Alem Douglas 
Published: May 2023

AbstractWe seek to provide practicable approximations of the two-stage robust stochastic optimization model when its ambiguity set is constructed with an f-divergence radius. These models are known to be numerically challenging to various degrees, depending on the choice of the f-divergence function. The numerical challenges are even more pronounced under mixed-integer first-stage decisions. In this paper, we propose novel divergence functions that produce practicable robust counterparts, while maintaining versatility in modeling diverse ambiguity aversions. Our functions yield robust counterparts that have comparable numerical difficulties to their nominal problems. We also propose ways to use our divergences to mimic existing f-divergences without affecting the practicability. We implement our models in a realistic location-allocation model for humanitarian operations in Brazil. Our humanitarian model optimizes an effectiveness-equity trade-off, defined with a new utility function and a Gini mean difference coefficient. With the case study, we showcase (1) the significant improvement in practicability of the robust stochastic optimization counterparts with our proposed divergence functions compared to existing f-divergences, (2) the greater equity of humanitarian response that the objective function enforces and (3) the greater robustness to variations in probability estimations of the resulting plans when ambiguity is considered.
When does 0–1 Principle Hold for Prefix Sums?
Authors: Morihata Akimasa 
Published: May 2023

AbstractKnuth’s 0–1 principle argues that the correctness of any swap-based sorting network can be verified by testing arbitrary sequences over Boolean values (i.e., 0 and 1). Voigtländer (Proceedings of the 35th ACM SIGPLAN-SIGACT symposium on principles of programming languages, POPL 2008, San Francisco, California, USA, January 7–12, 2008. ACM, New York, NY, pp 29–35, 2008. https://doi.org/10.1145/1328438.1328445) proved a similar result for prefix-sum networks that consist of associative binary operators: the correctness can be verified by testing arbitrary sequences and associative binary operators over three values, namely 0, 1, and 2. He raised the question of whether testing over Boolean values is sufficient if the binary operator is idempotent in addition to associative. This paper answers his question. First, there is an incorrect prefix-sum network for associative idempotent operators, the flaw of which cannot be detected by testing over Boolean values. Second, testing over Boolean values is sufficient if the binary operators are restricted to commutative in addition to associative and idempotent.
Predicting metastasis at initial diagnosis and radiotherapy effectiveness in patients with metastatic osteosarcoma
Authors: Chen Wenhao , He Xinyu , Yan Zhiyu , Lin Xiuquan , Bai Guannan 
Published: May 2023

AbstractOsteosarcoma is a primary malignant bone tumor affecting mostly children and adolescents. The overall 10 year survivals of patients with metastatic osteosarcoma are typically less than 20% in the literature and remain concerning. We aimed to develop a nomogram for predicting the risk of metastasis at initial diagnosis in patients with osteosarcoma and evaluate the effectiveness of radiotherapy in patients with metastatic osteosarcoma. Clinical and demographic data of patients with osteosarcoma were collected from the surveillance, epidemiology, and end results database. We randomly split our analytical sample into the training and validation cohorts, then established and validated a nomogram for predicting the risk of osteosarcoma metastasis at initial diagnosis. The effectiveness of radiotherapy was evaluated by performing propensity score matching in patients underwent surgery + chemotherapy and those underwent surgery + chemotherapy + radiotherapy, among patients with metastatic osteosarcoma. 1439 patients met the inclusion criteria and were included in this study. 343 of 1439 had osteosarcoma metastasis by the time of initial presentation. A nomogram for predicting the likelihood of osteosarcoma metastasis by the time of initial presentation was developed. In both unmatched and matched samples, the radiotherapy group demonstrated a superior survival profile comparing with the non-radiotherapy group. Our study established a novel nomogram to evaluate the risk of osteosarcoma with metastasis, and demonstrated that radiotherapy combined with chemotherapy and surgical resection could improve 10-year survival in patients with metastasis. These findings may guide the clinical decision-making for orthopedic surgeons.
Stress-controlled ratchetting in hypoplasticity: a study of periodically proportional loading cycles
Authors: Bauer Erich , Kovtunenko Victor A. , Krejčí Pavel , Monteiro Giselle A. , Runcziková Judita 
Published: May 2023

AbstractWe investigate rate-independent strain paths in a granular material generated by periodically oscillating stress cycles using a particular constitutive model within the hypoplasticity theory of Kolymbas type. It is assumed that the irreversible hypoplastic effects decay to zero when the void ratio reaches its theoretical minimum, while the void ratio is in turn related to the evolution of the volumetric strain through the mass conservation principle. We show that under natural assumptions on material parameters, both isotropic and anisotropic stress cycles are described by a differential equation whose solution converges asymptotically to a limiting periodic process taking place in the shakedown state when the number of loading cycles tends to infinity. Furthermore, an estimation of how fast, in terms of the number of cycles, the system approaches the limit state is derived in explicit form. It is shown how it depends on the parameters of the model, on the initial void ratio, and on the prescribed stress interval.
Coverage and similarity of bibliographic databases to find most relevant literature for systematic reviews in education
Authors: Heck Tamara , Keller Carolin , Rittberger Marc 
Published: May 2023

AbstractSystematic literature reviews in educational research have become a popular research method. A key point hereby is the choice of bibliographic databases to reach a maximum probability of finding all potentially relevant literature that deals with the research question analyzed in a systematic literature review. Guidelines and handbooks on review recommend proper databases and information sources for education, along with specific search strategies. However, in many disciplines, among them educational research, there is a lack of evidence on the relevance of databases that need to be considered to find relevant literature and lessen the risk of missing relevant publications. Educational research is an interdisciplinary field and has no core database. Instead, the field is covered by multiple disciplinary and multidisciplinary information sources that have either a national or international focus. In this article, we discuss the relevance of seven databases in systematic literature reviews in education, based on results of an empirical data analysis of three recently published reviews. To evaluate the relevance of a database, the relevant literature of those reviews served as the gold standard. Results indicate that discipline-specific databases outperform international multidisciplinary sources, and a combination of discipline-specific international and national sources is most efficient in finding a high proportion of relevant literature. The article discusses the relevance of the databases in relation to their coverage of relevant literature, while considering practical implications for researchers performing a systematic literature search. We, thus, present evidence for proper database choices for educational and discipline-related systematic literature reviews.
On the unfairness of actuarial fair annuities
Authors: Chen An , Vanduffel Steven 
Published: May 2023

AbstractActuarial fairness pertains to the situation in which the price of an insurance contract is equal to its expected outcome. We show that actuarial fairness leads to “unfairness” in that annuitants with higher survival rates can choose a better payoff in the sense of second-order stochastic dominance than those with lower survival rates. To deal with this issue, we propose equal utility pricing, i.e., we determine prices such that all contracts have the same (nonlinear) utility from the viewpoint of a third party (e.g., a social planner). This approach is of particular relevance with respect to the design of group self-annuitization schemes.
Vulture perceptions in a socio-ecological system: a case study of three protected areas in KwaZulu-Natal, South Africa
Authors: Manqele Nomthandazo S. , Selier S. A. Jeanetta , Taylor Jim , Downs Colleen T. 
Published: May 2023

AbstractVultures are presently the most threatened raptor guild in the world. Threats to vultures are numerous and mainly anthropogenic. Understanding human communities' relationship with threatened species can guide and strengthen conservation initiatives. We assessed the awareness, benefits, beliefs, threats, and conservation perspectives of people surrounding protected areas accommodating the few remaining vulture strongholds in KwaZulu-Natal, South Africa. We conducted a total of 450 semi-structured interviews and seven focus group discussions. Respondents demonstrated a strong awareness of vultures and reportedly derived benefits from having these avian scavengers in their localities. The most cited benefit (65%) was carrion removal. A predominant belief amongst local people was that vultures are potent in traditional medicine (66%); this was regarded by the majority of respondents (79%) as the main driver for the illegal killing of vultures. Most participants (84%) viewed vulture populations to have declined. Overall, local people demonstrated complex but predominantly positive perceptions towards vultures. Mounting evidence of the use of vultures in traditional medicine compels urgent action. We recommend co-learning-based engagements between resource users and conservation scientists.
Loyal Allies or Stubborn Establishment?
Authors: Böller Florian 
Published: May 2023

AbstractTo what extent was U.S. President Donald J. Trump’s populist foreign policy agenda supported by the Republican Party (GOP) in Congress? A bourgeoning literature on Congress and U.S. foreign policy has identified increasing partisan disagreement on international issues. Trump’s “America First” policy may have further incited division and ideological controversies. At the same time, the 45th U.S. president’s foreign and security policies were, to a large degree, at odds with traditional GOP policy positions. To understand executive–legislative relations on foreign and security policy during the Trump administration, and in particular the role of the GOP, this paper first investigates voting records in Congress during the Obama and Trump presidencies. The analysis reveals that the reaction to Trump’s “America First” doctrine was not uniform and that parts of the GOP asserted themselves against the president. To explain the sources of this variance, the article focuses on two policy areas with varied GOP positioning: arms control (pro Trump) and foreign aid (contra Trump). In sum, the analysis reveals that some Republicans with traditionalist views (the so-called GOP establishment) opposed some of Trump’s anti-internationalist policies, in particular those that contradicted long-standing GOP preferences regarding vital U.S. security interests. At the same time, Republicans supported Trump on issues where the GOP could continue its policy preference, on arms control in particular.
Making university mathematics matter for secondary teacher preparation
Authors: Wasserman Nicholas H. , Buchbinder Orly , Buchholtz Nils 
Published: May 2023

AbstractInternationally, questions about the perceived utility of university mathematics for teaching school mathematics pose an ongoing challenge for secondary mathematics teacher education. This special issue is dedicated to exploring this topic and related issues in the preparation of secondary mathematics teachers—by which we mean teachers of students with ages, approximately, of 12–18 years. This article introduces this theme and provides a semi-systematic survey of recent related literature, which we use to elaborate and situate important theoretical distinctions around the problems, challenges, and solutions of university mathematics in relation to teacher education. As part of the special issue, we have gathered articles from different countries that elaborate theoretical and empirical approaches, which, collectively, describe different ways to strengthen university mathematics with respect to the aims of secondary teacher education. This survey paper serves to lay out the theoretical groundwork for the collection of articles in the issue.
The impact of transsphenoidal surgery on pituitary function in patients with non-functioning macroadenomas
Authors: Mavromati Maria , Mavrakanas Thomas , Jornayvaz François R. , Schaller Karl , Fitsiori Aikaterini , Vargas Maria I. , Lobrinus Johannes A. , Merkler Doron , Egervari Kristof , Philippe Jacques , Leboulleux Sophie , Momjian Shahan 
Published: May 2023

Abstract
Purpose
Transsphenoidal surgery for non-functioning pituitary adenomas (NFPAs) can alter pituitary function. We assessed the rates of improvement and deterioration of pituitary function by axis and searched for predictive factors of these outcomes.

Methods
We reviewed consecutive medical files from patients having had transsphenoidal surgery for NFPA between 2004 and 2018. Pituitary functions and MRI imaging were analyzed prior and after surgery. The occurrence of recovery and new deficit were documented per axis. Prognostic factors of hormonal recovery and new deficits were searched.

Results
Among 137 patients analyzed, median tumor size of the NFPA was 24.8 mm and 58.4% of patients presented visual impairment. Before surgery, 91 patients (67%) had at least one abnormal pituitary axis (hypogonadism: 62.4%; hypothyroidism: 41%, adrenal insufficiency: 30.8%, growth hormone deficiency: 29.9%; increased prolactin: 50.8%). Following surgery, the recovery rate of pituitary deficiency of one axis or more was 46% and the rate of new pituitary deficiency was 10%. Rates of LH-FSH, TSH, ACTH and GH deficiency recovery were 35.7%, 30.4%, 15.4%, and 45.5% respectively. Rates of new LH-FSH, TSH, ACTH and GH deficiencies were 8.3%, 1.6%, 9.2% and 5.1% respectively. Altogether, 24.6% of patients had a global pituitary function improvement and only 7% had pituitary function worsening after surgery. Male patients and patients with hyperprolactinemia upon diagnosis were more likely to experience pituitary function recovery. No prognostic factors for the risk of new deficiencies were identified.

Conclusion
In a real-life cohort of patients with NFPAs, recovery of hypopituitarism after surgery is more frequent than the occurrence of new deficiencies. Hence, hypopituitarism could be considered a relative indication for surgery in patients with NFPAs.
Phylogenomics and deep convergence in cockroach hind-wing morphology
Authors: Evangelista Dominic A. , Nelson Dvorah , Varadínová Zuzana Kotyková , Legendre Frédéric 
Published: May 2023

Abstract
Despite regular advances in Blattodea systematics, several relationships remain controversial or untested in formal phylogenetic reconstructions. This common situation for understudied metazoan groups limits our power to answer questions about phenotypic evolution. In this study, we infer the evolutionary history of Blattodea using newly sampled taxa that improve phylogenetic resolution while also illuminating the evolutionary history of an unusual phenotype—the apically folded hind-wing. Taxa newly sequenced include those with a hind-wing apical fold (Anaplecta pulchella, A. pygmaea, A. sp. cf. malaysensis, Diplopterina parva, Prosoplecta semperi, Anaplectoidea klossi, and Oulopteryx illuminata sp. nov. that we describe herein, including its male genitalia) and other rare taxa (Dipteretrum hamstroemi, Duchailluia togoensis, Lauraesilpha mearetoi, Buboblatta vlasaki). The phylogenetic design utilizes 41 genes over 91 species in total, analyzed in a maximum likelihood and coalescent framework. To quantify the phylogenetic uncertainty of the analysis, support for various topologies is assessed. We find unambiguous support for the surprising position of Neotropical Oulopteryx (Oulopterygidae) as sister to New Caledonian/Australian Tryonicidae. This, and other phylogenetic findings, reveal that the apically folded hind-wing may have arisen nine times in Blattodea. Further investigations are needed, notably with an increased taxonomic sampling, to demonstrate stronger support for the placement of rogue taxa (e.g., Anaplecta) and to investigate the evolutionary correlates of wing evolution.
An old foe on peculiar paths: severe falciparum malaria in a Syrian refugee, possibly infected during migrant smuggling from Türkiye to Germany
Authors: Brozat Jonathan F. , Haverkamp Miriam , Hohlstein Philipp , Adams Jule K. , Wirtz Theresa H. , Klingel Hanna R. , Hürtgen Susanne , Hamesch Karim , Bruns Tony , Trautwein Christian , Jhaisha Samira Abu , Koch Alexander 
Published: May 2023

AbstractInfectious diseases and their imperative awareness gain major relevance through global warming and multi-continent refugee crises. Here, we demonstrate the challenges of malaria diagnosis, disease course, and treatment, including post-artesunate hemolysis in a Syrian refugee with severe falciparum malaria, most probably infected during migrant smuggling from Türkiye to Germany.
Multiparametric Ultrasound in Testicular Emergencies: State-of-the-Art
Authors: Paparella Maria Teresa , Eusebi Laura , Pagliara Martina Pia , Palladino Nicola , Sortino Giuseppe , Giannubilo Willy , Guglielmi Giuseppe 
Published: May 2023

Abstract
Purpose of Review
This review article aims to provide an overview of testicular multiparametric ultrasound features in emergency setting, to bring the reader up to date with new technologies and to provide insights into the ultrasound diagnosis of scrotal pathologies.

Recent Findings
Multiparametric ultrasound is increasingly recognized as a fundamental problem-solving technique in testicular diseases. Contrast-enhanced ultrasonography and elastography represent recent technologies that may be advantageous over conventional ultrasonography especially when diagnosis is controversial.

Summary
A wide range of acute diseases, including torsion, infection, ischaemia, and trauma, may affect the testis. These conditions represent frequently surgical emergencies, thus understanding their imaging appearance is imperative to help guide adequate management.