bluuebunny/crossref_metadata_2025_split huggingface dataset:
Button Position Following ACL Reconstruction in Hasan Sadikin Hospital Bandung
Authors: Telaumbana Tri Taufiqurachman , Utoyo Ghuna Arioharjo 
Published: February 2023

Background: Anterior cruciate ligament (ACL) reconstruction are done to restore function and preventing secondary osteoarthritis. The use of button has been popular as a method of femoral fixation during ACL reconstruction (ACLR) due to its securely easy and rapid application. The aim of this study was to review correct placement of tunnels for ACLR based on button position from radiographic examination at Hasan Sadikin Hospital Bandung. Methods: From July 2021 to August 2022 consecutive patients undergoing ACLR with single-bundle techniques were enrolled. Follow up were also done year after ACLR, patients underwent radiographic examination after surgery and clinical examination with International Knee Documentation Committee (IKDC) score. Results: There were 27 patients (3 women, 24 men) with mean age of 26.8 years (17 - 59). The angle measured between a line drawn along the femur diaphysis and the button position from anteroposterior x-ray was approximately 42.3o. In lateral view, 13 had shallow and high button placement, 4 had deep and high button placement and 10 had deep and low button placement (optimal). The optimal button placement for deep-shallow direction has a ratio of 42 to 80% (mean 61,14%) and for the high-low direction has ratio of 9 to 41% (mean 24,07%). In this study, all patients with optimal and non optimal position of laterally measured antero-posterior (AP) proximal-distal (PD) angle had increased IKDC (mean score 58.1 to 84.68). Discussion: X-ray, CT, fluoroscopy and direct endoscopic visualisation had been proposed for tunnel evaluation. This study used standard x-ray due to limitations from Badan Penyelenggara Jaminan Sosial-Kesehatan (BPJS) insurance. Button position should be across the tunnel opening with angle measured towards femur diaphysis to be around 39° in AP view. Lateral view should show optimal placement as mean ratio of 27% in the deep-shallow direction and 34% in the high low direction. IKDC was used as an outcome-measuring tool due to its comprehensive and complex questions. Conclusion: Correct button position for ACLR is important for the clinical outcome of the patients. This study shows that radiographic findings and patient’s clinical outcome is relevant to the quality of operative tunnel placement. A record of this finding is important for completeness of the radiological report. Button position from radiographic examination is usefull to evaluate correct placement of tunel for ACL reconstruction.
Characteristics of Tuberculous Spondylitis Patients Who Underwent Decompression and Posterior Stabilization Surgery At Dr Hasan Sadikin Hospital 2019-2021 Period
Authors: Prananda Aristu , Ismiarto Yoyos Dias 
Published: February 2023

Background: Tuberculous spondylitis is the classic presentation of extrapulmonary tuberculosis (TB). Bone and joint TB occurs in 5-10% of the population. Surgical procedures are performed to prevent worsening of neurological deficits, maintain vertebral stability, and early mobilization. The purpose of this study was to determine the characteristics of tuberculous spondylitis patients who underwent decompression and posterior Stabilization surgery at Hasan Sadikin Hospital, Bandung for the 2019-2021 period. Method: This study uses a descriptive design with a cross-sectional approach obtained from medical records at Hasan Sadikin Hospital in Bandung for the 2019-2021 period, the study uses total sampling. The inclusion criteria in this study were cases of tuberculous spondylitis who underwent decompression and posterior stabilization surgery. The exclusion criteria in this study were TB spondylitis patients who have not experienced bone destruction and respond to therapy. The data was then processed using Microsoft Excel and the 25th edition of SPSS and then presented as research results. Results: There were 68 subjects in this study consisting of 28 men and 40 women, aged 11–73 years with a mean age of 35 years. In this study, the chief complaint was back pain in 85% of cases, spinal deformity 54% of cases, and neurological deficits in 36% of cases. Most tubercular lesions occurred in the thoracic (53%), lumbar (45%), cervical (1%). The study also found that 16% had diabetes mellitus, 11% had heart disease, , 10% had hypertension. 82% of study subjects stated a decrease in pain as assessed using VAS. Conclusion: Characteristics of tuberculous spondylitis patients who underwent decompressive and posterior stabilization surgery at Hasan Sadikin Hospital for the period 2019-2021 mostly occurred at women with the age of 11-73 years, with dominan complaints in the form of back pain (85%), and then spinal deformity, and paralysis, and findings of tubercular lesions Mostly in the thorax (53%), and then lumbar, and cervical, and there was a decrease in the value of the VAS after decompression and posterior stabilization surgery at Hasan Sadikin Hospital.s
PCL Reconstruction Surgery in Third Grade PCL Rupture: A Case Series
Authors: Albar Husnul Fuad , Yudhadibrata Permana , Sitohang Robby Oscar 
Published: February 2023

Objective: The PCL is the largest and strongest intraarticular ligament of the knee joint, comprising of 2 functional bundles: the larger anterolateral bundle (ALB) and the smaller posteromedial bundle (PMB). Posterior cruciate ligament (PCL) tears comprise 3% of outpatient knee injuries. The treatment of complete, isolated PCL tears remains controversial. Some studies have reported good outcomes after conservative treatment of partial PCL tears, while others have reported poor results at long-term follow-up with disabling symptoms and functional limitations. This case series reported the first experience of PCL reconstruction in our institution and its associated outcome. Methods: This prospective case series was conducted from January to December 2021. Two patients were included in this case series. All the patients were diagnosed with PCL tear by an Orthopaedic surgeon. clinical examination, knee radiograph, and MRI were obtained in both patients. All patients underwent arthroscopic PCL reconstruction by a single senior Orthopaedic surgeon. Physical therapy was performed after the surgery. Clinical evaluation was followed up for 9 months. The outcome in this case series was the posterior drawer test and range of motion. Result: Two patients were included in this case series. A favorable outcomes were noted following PCL reconstruction surgery. There were negative posterior drawer test, posterior sag sign, and full range of motion in both patients. Conclusion: A PCL reconstruction surgery provided a satisfactory clinical outcome in terms of posterior drawer test, posterior sag sign, and range of motion. PCL reconstruction surgery is recommended in patients who present with grade 3 PCL injury.
Association of COVID-19 Lockdown With Increased Rate of Cyclops Syndrome in Patients With Unexpected Home-Based Self-Guided Rehabilitation After ACL Reconstruction
Authors: Bouguennec Nicolas , Orce Aida , Laboudie Pierre , Pelletier Simon , Dexhelet Jeremy , Graveleau Nicolas 
Published: February 2023

Background: The risk of cyclops syndrome increases significantly after anterior cruciate ligament (ACL) reconstruction (ACLR) if complete extension is not recovered before the sixth postoperative week. The lockdown in France due to the COVID-19 pandemic led to an absence of supervised rehabilitation, requiring unexpected self-rehabilitation in patients who underwent ACLR just before lockdown. Purpose: To determine the rate of cyclops syndrome after ACLR in patients who underwent self-rehabilitation during lockdown. Study Design: Cohort study; Level of evidence, 3. Methods: A total of 75 patients receiving a hamstring graft for ACLR during the COVID-19 pandemic between February 10, 2022, and March 16, 2020, carried out self-rehabilitation during part of their first 6 postoperative weeks using exercise videos on a dedicated website. Clinical examination was performed at a minimum 1-year follow-up with International Knee Documentation Committee (IKDC), Lysholm, Tegner, and ACL–Return to Sport after Injury (ACL-RSI) scores. This group was compared with a matched-pair control group of 72 patients who underwent surgery in 2019 and completed postoperative supervised rehabilitation with a physical therapist. Rates and reasons for second surgery (arthrolysis, meniscal procedure) were also recorded. Results: In the COVID group (n = 72; 3 patients were lost to follow-up), the mean follow-up was 14.5 ± 2.1 months (range, 13-21) and rate of reoperation for clinical cyclops syndrome was 11.1% (n = 8). The rate of cyclops syndrome was significantly lower (1.4%) in the control group ( P = .01). In the COVID group, 8 patients underwent anterior arthrolysis at a mean of 8.6 months after the primary surgery, and 4 patients underwent another surgical intervention (meniscal procedure [n = 3], device removal [n = 1]). In the COVID group, mean Lysholm was 86.6 ± 14.1 (range, 38-100), Tegner was 5.6 ± 2.3 (range, 1-10), subjective IKDC was 80.3 ± 14.7 (range, 32-100) and ACL-RSI score was 77.3 ± 19.7 (range, 33-100). Conclusion: The rate of cyclops syndrome after ACLR was significantly greater in the COVID group versus the matched controls. The dedicated website was not effective at supporting self-guided rehabilitation and could benefit from interactive improvements so it is at least as effective as supervised rehabilitation.
The Populus alba cationic cell-wall-bound peroxidase (CWPO-C) regulates plant growth, lignin content and composition in poplar
Authors: Yoshikay-Benitez Diego Alonso , Ohira Kaori , Banerjee Kasturi , Fujita Koki , Shigeto Jun , Tsutsumi Yuji 
Published: February 2023

AbstractCationic cell-wall-bound peroxidase (CWPO-C) from Populus alba is the only Class III peroxidase that has been shown to be able to oxidize high molecular weight lignin polymers from sinapyl alcohol and previously, has been believed to be a lignin polymerization-specific peroxidase. However, using an Arabidopsis heterologous expression system, we showed recently that CWPO-C contributes to differentiation or early growth and is involved in auxin catabolism. In this study, to clarify the function of CWPO-C in poplar, we analyzed CWPO-C gene expression and phenotypic changes with CWPO-C overexpression and suppression. Real-time PCR and monitoring promoter activity of CWPO-C using β-glucuronidase (GUS) assay revealed that CWPO-C was strongly expressed in immature tissues, such as the upper stem, axillary buds, and young leaves, in addition to expression in developing xylem. In transgenic poplars in which the expression of CWPO-C was upregulated or suppressed, changes in stem growth, gravitropism bending time, lignin content and syringyl/guaiacyl (S/G) composition were observed. Overexpressing CWPO-C enhanced stem growth and gravitropic response (shorter bending time). With suppressed CWPO-C expression, the lignin content was reduced approximately 45% and the S/G ratio decreased by half. These results strongly suggest that CWPO-C plays a role in differentiation and early growth, as well as in lignin polymerization.
Traces of Introgression from cAus into Tropical Japonica Observed in African Upland Rice Varieties
Authors: Beye Abdoulaye , Billot Claire , Ronfort Joëlle , McNally Kenneth L. , Diouf Diaga , Glaszmann Jean Christophe 
Published: February 2023

Abstract
Background
Asian rice Oryza sativa, first domesticated in East Asia, has considerable success in African fields. When and where this introduction occurred is unclear. Rice varieties of Asian origin may have evolved locally during and after migration to Africa, resulting in unique adaptations, particularly in relation to upland cultivation as frequently practiced in Africa.

Methods
We investigated the genetic differentiation between Asian and African varieties using the 3000 Rice Genomes SNP dataset. African upland cultivars were first characterized using principal component analysis among 292 tropical Japonica accessions from Africa and Asia. The particularities of African accessions were then explored using two inference techniques, PCA-KDE for supervised classification and chromosome painting, and ELAI for individual allelic dosage monitoring.

Key Results
Ambiguities of local differentiation between Japonica and other groups pointed at genomic segments that potentially resulted from genetic exchange. Those specific to West African upland accessions were concentrated on chromosome 6 and featured several cAus introgression signals, including a large one between 17.9 and 21.7 Mb. We found iHS statistics in support of positive selection in this region and we provide a list of candidate genes enriched in GO terms that have regulatory functions involved in stress responses that could have facilitated adaptation to harsh upland growing conditions.
Infection caused by Lawsonella clevelandensis after breast augmentation with autologous fat grafting: a case report
Authors: Zhou Feng , Zhang Jun , Gong Lunli , Wang Guobao , Khan Aawrish , Cui Haiyan 
Published: February 2023

Abstract
Background
Lawsonella clevelandensis is one recently documented anaerobic, which is partially acid-fast. Nevertheless, it is rarely found to be associated with human infections, especially in scope of plastic and cosmetic surgery before our patient who was performed breast augmentation with autologous fat grafting. Breast augmentation is becoming popular, the most common post-surgery complication of which is bacterial infection.

Case presentation
A 29-year-old female who was found swelling in her right breast and fever after breast augmentation surgery with autologous fat grafting was administered. Before administration, she had been treated with antibiotics (details unknown) for more than 1 month without any significant improvements. After administration, she was treated with intravenous antibiotic empirically and repeated debridement via Vaccuum Sealing Drainage (VSD). And samples of the necrotic tissues and pus collected in surgery were sent for microbiological testing. However, routine examination failed. Thus samples were further collected and sent to Genoxor Medical & Science Technology Inc. (Shanghai, China) to conduct Next-Generation Sequencing (NGS). Surprisingly Lawsonella clevelandensis was determined. Accordingly, sensitive antibiotic was applied in concert with thorough debridement and drainage and finally her condition was completely reversed with wound closure gradually.

Conclusion
Complications of breast augmentation with autologous fat graft are various, of which infection is most common. Rare pathogen such as Lawsonella clevelandensis infection in human is rare in clinical practice. Moreover, it is difficult to differentiate from non-tuberculous mycobacterium for its partial acid resistance, difficulty to culture and abscess formation. How to determine diagnosis of Lawsonella clevelandensis infection accurately come to be critical In our report, NGS is recommended as a useful method to identify the pathogen, which may provide us a novel tool for refractory wound.
‘Just snap out of it’ – the experience of loneliness in women with perinatal depression: a Meta-synthesis of qualitative studies
Authors: Adlington Katherine , Vasquez Cristina , Pearce Eiluned , Wilson Claire A. , Nowland Rebecca , Taylor Billie Lever , Spring Sarah , Johnson Sonia 
Published: February 2023

AbstractBackgroundPregnancy and the arrival of a new baby is a time of great transition and upheaval. Women often experience social isolation and loneliness at this time and may develop depression, particularly in the postnatal period. Qualitative studies have reported that loneliness is also a feature of perinatal depression. However, until now there has been no attempt to synthesise research exploring the links between loneliness and perinatal depression. This study’s aim was to explore existing qualitative evidence to answer two research questions: What are the experiences of loneliness for women with perinatal depression? What helps and what makes loneliness worse for women with perinatal depression?MethodsA qualitative meta-synthesis retrieved primary qualitative studies relevant to the research questions. Four electronic databases were systematically searched (Ovid MEDLINE®; PsycINFO; Embase; Web of Science). Papers were screened according to pre-defined inclusion criteria and assigned a quality score. Thematic analysis was used to identify major overarching themes in the literature.ResultsTwenty-seven relevant qualitative studies were included. Themes relating to the interaction between perinatal depression and loneliness included self-isolation and hiding symptoms due to stigma of perinatal depression and fear of judgement as a ‘bad mother’; a sudden sense of emotional disconnection after birth; and a mismatch between expected and actual support provided by partner, family and community. There was also a double burden of loneliness for women from disadvantaged communities, due to increased stigma and decreased social support. Validation and understanding from healthcare professionals, peer support from other mothers with experience of perinatal depression, and practical and emotional family support were all important factors that could ameliorate loneliness.ConclusionsLoneliness appears to play a central role in the experience of perinatal depression based on the frequency with which it emerged in women’s accounts. The findings provide a foundation for the development of further theories about the role of loneliness in perinatal depression and evidence in which future psychological and social intervention design processes can be rooted. Addressing stigma and offering culturally appropriate professional and peer support are potential targets for interventions that could help women with perinatal depression, particularly in disadvantaged communities, feel less lonely.Trial registrationProspero registration:https://www.crd.york.ac.uk/prospero/display_record.php?RecordID = 251,936.
Associations between socioeconomic status and risk of obesity and overweight among Chinese children and adolescents
Authors: Ke Youzhi , Zhang Shikun , Hao Yueran , Liu Yang 
Published: February 2023

Abstract
Background
In China, the threat of obesity and overweight in children and adolescents is developing quickly. It may be possible to lower the risk of obesity and overweight in children and adolescents by understanding the factors that drive these conditions. Therefore, this study aimed to investigate the association between SES and risk of obesity and overweight among children and adolesecnts in China’s provinces of Jiangsu, Anhui, Zhejiang, and Shanghai.

Methods
Chinese children and adolescents (n = 2,746; 46.3% boys) were recruited using multistage sampling. SES was measured using self-reported questionnaires, the specific indicators were parental education, perceived family wealth, and Family Affluence Scale II. Height and weight were measured and used to calculate body mass index (BMI, categorized into obesity or overweight). The definition of obesity or overweight was based on the Chinese standard "Screening for obesity and overweight among school-age children and adolescents". Descriptive statistics, independent sample t-tests, and a Chi-square test were used to report the sample characteristics and analyse BMI differences across different sociodemographic groups. A binary logistic regression was then applied to analyse the association of SES indicators with BMI in children and adolescents.

Results
Overall, 22.5% of children and adolescents were obese or overweight. Participants with medium and high maternal education levels were 1.48 [95% CI 1.15–1.91] and 1.47 [95% CI 1.03–2.11] times more likely to be obese/overweight. Girls with medium maternal education levels were 1.70[95% CI 1.21–2.40] times more likely to be obese/overweight. For boys, no association was observed. Junior middle school students with medium maternal education levels were 1.51[95% CI 1.10–2.07] times more likely to be obese/overweight. Participants with medium or high FAS, perceived family wealth, or paternal education levels were not associated with obesity/overweight.

Conclusions
The findings of this study indicated a positive association between SES and risk of overweight/obesity in girls, suggesting that maternal education level may have a substantial impact on future prevention efforts for these conditions in girls. To increase the effectiveness of interventions, longitudinal studies are necessary to better understand the causal association between SES and obesity/overweight.
Girl predominance in trampoline-related forearm shaft fractures and their increasing incidence since 2000
Authors: Stöckell Markus , Pikkarainen Ella , Pokka Tytti , Sinikumpu Juha-Jaakko 
Published: February 2023

Abstract
Background
There are reports of increasing incidence of forearm shaft fractures in children. Their treatment has been preferably nonoperative but surgical fixation has gained popularity due to elastic stable intramedullary nailing. We aimed to study whether the incidence of pediatric both-bone forearm shaft fractures and their operative care have changed since year 2000. Trampoline injuries, in particular, and their treatment, re-displacement and short-term outcomes were the secondary outcomes of the study.

Methods
A population-based study in the geographic catchment area of Oulu University Hospital district in 20-years of time period (2000 – 2019) was performed. Altogether 481 diaphyseal both-bone forearm fractures in children (< 16 years) were included. Age- and sex-related incidence rates were determined, by using the official numbers of the population-in-risk by Statistics Finland. Trampoline jumping and other types of injury were reviewed, as well as particulars of treatment and outcomes.

Results
The incidence of diaphyseal both-bone forearm fractures increased from 9.4/100 000 in 2000–2001 to 41.7/100 000 in 2018–2019 (P < 0.001). Surgical treatment increased respectively (from 8.8/100 000 in 2000–2001 to 35.3/100 000 in 2018–2019, P < 0.0001). Trampoline injuries explained one in three (29%) of all fractures; they increased from 0% in 2000–2001 to 36.6% in 2018–2019 (P < 0.001). During the last four years of the study (2016–2019), most trampoline-related injuries occurred among girls (61.2%), compared to boys (38.8%) (P = 0.031). Trampoline-related injuries comprised 46.9% of all fractures in girls, compared to 26.0% among boys (Diff. 20.8%, 4.7% to 36.1%, P = 0.009). The mean age of the patients elevated from 6.4 years (2000–2001) to 8.6 years (2018–2019) (P = 0.015). Boys predominated (69.6%) in 2000–2009 but during the last ten years, there was no statistical difference in distribution between the genders (males 54.6%, P = 0.11).

Conclusions
During the twenty-year’s of study period, the incidence of pediatric diaphyseal forearm fractures increased fivefold. Trampolining was the most usual single reason for the fractures. More attention should be focused to increase the safety of trampoline jumping, in particular among the girls.