bluuebunny/crossref_metadata_2025_split huggingface dataset:
INNOVACIÓN EN LOS MORTEROS DE CAL/PUZOLANA PARA UNA CONSTRUCCIÓN SOSTENIBLE DE VIVIENDAS SOCIALES
Authors: Villca Pozo Ariel Rey , Condori Huanca Fortunato 
Published: June 2023

Como consecuencia del descubrimiento del cemento portland, los morteros de cal/puzolana han sido sustituidos parcialmente por tener bajas resistencias mecánicas a tiempos cortos de curado, a diferencia del cemento que posee altas resistencias mecánicas iniciales de curado. Este estudio presenta la posibilidad de utilizar geopolímeros en morteros cal/puzolana para mejorar este inconveniente técnico. Estos geopolímeros fueron fabricados con el catalizador gastado de craqueo catalítico activado con una mezcla de Na2O y Na2SiO3, y también fueron activados con una mezcla de Na2O y la ceniza de cascara de arroz como fuente de sílice. Se sustituye el 10 y 40 % en peso del mortero cal/puzolana por el geopolímero. Los morteros híbridos cal/puzolana-geopolímero desarrollaron la formación de nuevos productos en la reacción que mejoraron la resistencia mecánica de los morteros desde las primeras horas de curado, llegándose a obtener a 1 día de curado una resistencia similar a la que se obtiene para un mortero cal/puzolana a los 270 días de curado. Por este motivo, estos conglomerantes podrían ser empleados en la preparación de materiales de construcción más sostenibles para la auto-construcción de viviendas sociales.

Fecha de recepción: 14/11/2022.Fecha de evaluación: 01/02/2023.Fecha de aprobación: 15/05/2023.
ANÁLISIS DEL COMPORTAMIENTO DE CAPTACIONES FINANCIERAS Y MEDICIÓN DEL RIESGO DE LIQUIDEZ APLICANDO EL VALUE AT RISK, EN UNA ENTIDAD FINANCIERA DE VIVIENDA, 2017-2021
Authors: Ramirez Choque Felix 
Published: June 2023

La Gestión del Riesgo de liquidez toma amplia preponderancia, dado que los entes regulatorios le asignan importancia por la fragilidad que existe ante la materialización del Riesgo y el efecto contagio que genera.
La liquidez en cualquier Entidad de Intermediación Financiera es de suma importancia, debido a que representa la función de conexión directa con el cliente a través de la interrelación de depósitos y retiros, la determinación de los niveles de disponibilidad inmediata debe estar acorde a la relación Rentabilidad y Riesgo, para que genere una mayor cuantía de valor en la operativa para afrontar exigencias que surjan.
Es substancial definir procedimientos cuantitativos, considerando la evolución temporal, para el diseño de estrategias y disminuir la exposición al Riesgo de liquidez con procesos formales de identificación, medición, control, mitigación y divulgación, con enfoque basado en Riesgos.
El Valor en Riesgo de liquidez, resulta ser una herramienta útil, en relación a fundamentos técnicos con modelos formales que denotan robustecer la gestión de riesgo definiendo un marco diferencial para la toma de decisiones financieras y ofrecer soporte para su generalización ampliable a cualquier tipo de Entidad de Intermediación Financiera con una base de datos consolidada de al menos cinco años.
Editorial: Launching a New Era of Scientific Discovery: Introducing the First Volume of the BioMed Target Journal
Authors: Salihi Abbas 
Published: June 2023

Advances in medical sciences, pharmacology, nursing, biology, biochemistry, biophysics, and biomedical sciences could influence people's lives. The Biomed Target Journal (BMTJ), a peer-reviewed journal that highlights substantial and innovative contributions in these fields, is officially published. As we embark on this exciting journey, we want to provide a platform for academics, physicians, and pharmacologists to share cutting-edge findings and promote multidisciplinary collaboration.
The BMTJ aims to enhance science and encourage groundbreaking discoveries. The highest academic standards are maintained by our editors, reviewers, and researchers. By publishing rigorous, evidence-based publications, we want to advance medical research.Cooperation and diverse research are essential to solving today's complex healthcare problems. By bringing together experts from different fields, the BMTJ hopes to foster collaboration. We encourage cross-disciplinary interactions to advance new areas of research and science. Global collaboration and information sharing are important to the BMTJ. As an open-access journal, we aim to make scientific material accessible to researchers, healthcare professionals, and the public worldwide. We strive to encourage dialogue, creativity, and equitable access to scientific discoveries by lowering information barriers.
Quality, rigor, and integrity are BMTJ priorities. Only scientifically legitimate and important research is published through our rigorous peer-review process. By following these criteria, we want to build reader trust and scientific integrity. We invite academics, clinicians, and pharmacologists to submit new material to the BMTJ as we launch this exciting endeavor. Original research articles, systematic reviews, meta-analyses and case studies that improve healthcare are welcome.
With the BMTJ, we are thrilled to contribute to the everchanging fields of medical sciences, pharmacology, nursing, biology, biochemistry, biophysics, and biomedical sciences. We are excited to publish the first volume and promote global research. Let's work together to expand knowledge, encourage collaboration, and create innovative advancements that will improve global health and well-being. Welcome to the Biomed Target Journal, where scientific skills thrive, innovations grow, and healthcare's future is built!
MONITORING THE INFLUENCE OF COAL MAN-MADE LANDSCAPES ON THE ATMOSPHERE OF COAL-MINING REGIONS
Authors: Skopichenko E.I. , Vergelska V.V. , Vergelska N.V. , Golovchenko D.M. , Ozirskaya S.M. 
Published: June 2023

According to studies of recent decades, Ukraine is one of the most polluted and environmentally problematic countries in the world. The level of pressure on the environment in Ukraine has increased significantly during the fighting, starting in 2014 in the Donbas, and has deteriorated significantly since 2022. At the present stage of social development, the process of formation and implementation of an effective and efficient state environmental policy, taking into account the existing natural resource potential of the regions and the possibility of their transformation into the national economy, is of particular importance. In recent years, although there has been a decline in production, the annual level of environmental pollution is quite high, including due to incorrect reclamation after the closure of coal mining enterprises. The influence of human activity on the structures of the Earth's surface, today, is especially noticeable in the mining regions, where significant masses of rocks have been brought to the surface and new structures have been created. Human intervention in the process of landscape development leads to new relationships between its components due to the processes of oxidation of rocks brought to the surface and the release of energy and gas mixtures into the atmosphere.
The coal-mining regions of Ukraine, which are in a state of deep technogenic changes and transformations, have a chance to use the results of intensive geological and technogenic realities for the conclusions of the search for the scientific foundations of nature management and environmental conservation. At the present stage of social development, which is characterized by the acceleration of the pace of scientific and technological progress on the one hand, the aggravation of environmental problems and environmental pollution, on the other hand, the process of formation and implementation of an effective and efficient state environmental policy, taking into account the existing natural resource potential of the regions, is of particular importance.
Pengaruh Kompensasi terhadap Kinerja Aktivis KSP Credit Union (CU) Keling Kumang di Branch Office Sekadau
Authors: Fitria Elvi  
Published: June 2023

Compensation, definitely, affects the performance of the activists. The compensation, whether sufficient or not, will affect the performance of the activists. If the compensation given is sufficient, thus the activist will have good working performance. This study aims to argue the effect of the compensation variable on the performance of KSP CU Keling Kumang activists. Based on the previous research, enriched with supporting theories proposed by the experts using the SPSS program as a statistical data processing tool. The type of the research is descriptive and qualitative. In this study, the researcher used a questionnaire as a data collection tool and then processed it using a Simple Linear Regression analysis tool to prove that compensation indeed affect the performance of KSP CU Keling Kumang activists at Branch Office Sekadau and the results from the regression equation Y = 40,972 + 0.136 X.
Multitasking og acting
Authors: Martinsen Watz Siw , Ingstad Kari 
Published: June 2023

Det er et økende behov for å rekruttere og beholde helsefagarbeidere. Mye av ansvaret for pleien er overført til kommunene, liggetiden på sykehus er gått ned og pasientene er sykere når de kommer hjem. I en slik kompleks og emosjonell arbeidskontekst skal helsefagarbeiderlærlingene utvikle seg til kompetente yrkesutøvere samfunnet trenger. Helsefagarbeiderutdanningen og praksisfellesskapet i hjemmesykepleien må tilrettelegge for kompetanse som gjør lærlingene i stand til å møte arbeidslivets krav og forventninger. Forskningsspørsmålet denne artikkelen belyser er: Hvordan erfarer og håndterer lærlinger i helsearbeiderfaget krav og forventninger i læretiden i hjemmesykepleien?
Individuelle intervjuer og observasjoner ble vurdert som en akseptabel fremgangsmåte. 12 lærlinger i helsearbeiderfaget ble intervjuet individuelt, og to av lærlingene ble observert av førsteforfatter gjennom 5 dager i praksis. Studien formidler hvordan helsefagarbeiderlærlinger manøvrerer i feltet som består av krav og forventninger, og hvor tiden til den enkelte pasient er tilmålt. Analysen viser at lærlingene håndterer krav og forventninger gjennom multitasking, acting, prioritering, tilpasning og grensesetting. De bygger bro mellom formelle og uformelle krav og forventninger ved at de utfører flere oppgaver samtidig, har dobbel oppmerksomhet i situasjoner, de skjuler innvendig stress, og de tilpasser seg pasientene samtidig som de prioriterer og setter grenser. Disse ferdighetene synes nødvendig å utvikle for å kunne ivareta formelle krav via en vedtaksbasert arbeidsliste, og uformelle krav som oppstår i møte med en kompleks gruppe av hjemmeboende pasienter.
MK8617 inhibits M1 macrophage polarization and inflammation via the HIF-1α/GYS1/UDPG/P2Y14 pathway
Authors: Qian Lingling , Chen Xiao-qin , Kong Deyang , Wang Gaoyuan , Cao Yun , Xiao Yingchun , Cao Jing-yuan , Zou Chunbo 
Published: June 2023

Background
Nonresolving inflammation is a major driver of disease and needs to be taken seriously. Hypoxia-inducible factor (HIF) is closely associated with inflammation. Hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs), as stabilizers of HIF, have recently been reported to have the ability to block inflammation. We used MK8617, a novel HIF-PHI, to study its effect on macrophage inflammation and to explore its possible mechanisms.

Methods
Cell viability after MK8617 and lipopolysaccharide (LPS) addition was assessed by Cell Counting Kit-8 (CCK8) to find the appropriate drug concentration. MK8617 pretreated or unpretreated cells were then stimulated with LPS to induce macrophage polarization and inflammation. Inflammatory indicators in cells were assessed by real-time quantitative reverse-transcription polymerase chain reaction (qRT-PCR), western blot (WB) and immunofluorescence (IF). The level of uridine diphosphate glucose (UDPG) in the cell supernatant was measured by ELISA. Purinergic G protein-coupled receptor P2Y14, as well as hypoxia-inducible factor-1α (HIF-1α) and glycogen synthase 1 (GYS1) were detected by qRT-PCR and WB. After UDPG inhibition with glycogen phosphorylase inhibitor (GPI) or knockdown of HIF-1α and GYS1 with lentivirus, P2Y14 and inflammatory indexes of macrophages were detected by qRT-PCR and WB.

Results
MK8617 reduced LPS-induced release of pro-inflammatory factors as well as UDPG secretion and P2Y14 expression. UDPG upregulated P2Y14 and inflammatory indicators, while inhibition of UDPG suppressed LPS-induced inflammation. In addition, HIF-1α directly regulated GYS1, which encoded glycogen synthase, an enzyme that mediated the synthesis of glycogen by UDPG, thereby affecting UDPG secretion. Knockdown of HIF-1α and GYS1 disrupted the anti-inflammatory effect of MK8617.

Conclusions
Our study demonstrated the role of MK8617 in macrophage inflammation and revealed that its mechanism of action may be related to the HIF-1α/GYS1/UDPG/P2Y14 pathway, providing new therapeutic ideas for the study of inflammation.
Effect of Dexamethasone Addition to Local Anesthetics in Supraclavicular Brachial Plexus Block
Authors: Abdullah-Hel-Baki Md. , Ahmed Kawser , Neher Jaitun , Barman Nirmal Kumar , Hossein Md. Monwar , Sharma Ashutosh Dev , Shil Shiladitya 
Published: June 2023

Background: The addition of dexamethasone to local anesthetics in supraclavicular brachial plexus block has been studied to evaluate its impact on block onset and duration, potentially enhancing the efficacy of regional anesthesia.
Objective: In this study our main goal is to evaluate the effect of dexamethasone added to local anaesthetics on the onset and duration of supraclavicular brachial plexus block.
Methods: This cross-sectional study was carried out at tertiary hospital from January 2022 to January 2023. Where 100 adult patients undergoing various orthopaedic surgeries on forearm and around the elbow under supraclavicular brachial plexus block were selected and divided into 2 groups of 50 each. In group-A patients received 35 ml of mixture of lignocaine 2%, bupivacaine 0.5% while in group-B patients received the same amount of local anaesthetics with dexamethasone (8 mg). The onset of sensory and motor block and duration of analgesia in two groups were compared and development of complications were observed.
Results: Both Group A (48%) and Group B (42%), where most of the patients in the research are located, have a median age of 41 years. There were 80% males and 20% females in Group A. There were ninety males and ten females in Group B. There was a statistically significant (p 0.05) early onset of sensory and motor block in group B. The analgesic effect lasted much longer in group B (p 0.001) than in group A. In addition, 45% of group A participants were diagnosed with Horner's syndrome, and 7% had Dyspnoea or chest pain. The recurrent laryngeal nerve was blocked in 3% of patients, whereas 2% had insufficient occlusion. In group B, 31% of people experienced horners syndrome, and 5% had Dyspnoea or chest pain. Two percent of patients had a block of the recurrent laryngeal nerve, with one percent experiencing an inadequate block.
Conclusion: Addition of dexamethasone to 1.5% lidocaine with adrenaline in supraclavicular brachial plexus block speeds the onset and prolongs the duration of sensory and motor blockade. However, the use of dexamethasone to prolong the effects of local anesthetics is not encouraged. It might be useful in situations when epinephrine use is limited (such as in hypertension or cardiovascular disease).
Pattern of Liver Function Test in Scrub Typhus Cases: A Hospital Based Observational Study in a Tertiary Care Center in Nepal
Authors: Sah Sanjay Kumar , Sah Navin Kumar , Singh Alok Kumar , Yadav Nirdhan , Marasini Surendra 
Published: June 2023

Background and Aim: Scrub typhus, a potentially severe but treatable infection is a major cause of acute non-malarial febrile illness in children in the rural tropics. The present study aims to explore the association between the liver function tests in the cases of scrub typhus and correlate the levels of these parameters with the severity of the scrub typhus infections, their clinical risk characteristics that may be used to forecast disease severity under routine clinical practice.
Methodology: This prospective observational study, conducted at National Medical College Teaching Hospital, a tertiary care referral teaching hospital situated in province two of Nepal over a period of 7 months (November, 2021- May 2022) enrolled 75 scrub typhus cases and their liver function tests were done following standard guidelines.
Results:There were deranged liver function tests in the participants. The mean Aspartate Transaminase, Alanine Transaminase, Total Bilirubin and Albumin were425.48 ± 505.56 U/L, 368.54 ± 402.22 U/L, 3.8 ± 3.1 mg/dL and 3.10 ± 0.8 g/dL, respectively. Most of the cases presented with hypoalbuminemia (66.7%), cardiac dysfunction (64%), acute kidney injury (61%) and hepatitis (60%). About 9 % of the subjects presented as multiorgan dysfunction syndrome (MODS).
Conclusion: Scrub typhus cases presents with deranged liver function tests results and the values can be helpful in assessment of the disease severity and outcome.
Factors Leading to Conductive Hearing Loss among Children Living in Delhi Slum Areas
Authors: Chandel Swati , Singh Akanksha , Harit Anshika , Bose Dipak Kumar , Najeeb S. M. Tarique , Gupta Neena 
Published: June 2023

Background: Middle-ear diseases in children pose a significant burden to the healthcare system. Recurrent upper respiratory tract infections, cold, and cough often initiate middle ear disease. It results in mild to moderate hearing impairment that can be detrimental to the child's linguistic development. It can further lead to behavioural and cognitive problems. The study was designed to establish a relationship between common middle pathologies like CSOM and OME with hearing loss in children.
Objective: To determine the prevalence of middle ear pathology and its association with hearing loss in slum children of Delhi.
Methods: A study was conducted with 269 children aged five to ten years. The children were screened by otoscopic examination, followed by Tympanometry and then by Pure Tone Audiometry.
Results: The prevalence of middle ear problems was 24.2%, out of which the prevalence of Chronic Suppurative Otitis Media (CSOM) was 10.8%, Otitis media with effusion (OME) was 12.3% and Acute Otitis Media (AOM) was 1.1%. A significant correlation (p< 0.005) was found between hearing loss and middle ear pathology like CSOM and OME. Out of the 65 children with ear pathology, hearing loss was detected in 55 children, out of which 29 children with CSOM, moderated conductive hearing loss was detected in 28 children and out of 33 OME children, mild to moderate conductive hearing loss was detected in 26 children.
Conclusion: The article highlights the high prevalence of middle ear pathology in underprivileged children. The study also concludes the high probability of conductive hearing loss in these children. It is recommended that there is more need for awareness for early detection and treatment of middle ear infection to avoid any language and behavioural problems in the future. Also, the disparity between children living in urban and rural areas needs to be bridged.
Solid Sample Preparations and Applications for X‐Ray Fluorescence Analysis
Authors: Ichikawa Shintaro , Nakamura Toshihiro 
Published: June 2023

Abstract
X‐ray fluorescence (XRF) spectrometry is routinely employed for the simple and convenient determination of the content of the major and minor elements composing solid and powdered samples without the need to dissolve the samples. Along with developments in instrument components and analytical techniques, spectrometers have become increasingly smaller and automated. Modern XRF instruments are used by nonspecialists in various fields as well as by experienced analysts; these nonspecialist users may have little knowledge of analytical techniques and may omit to verify their results or may not be aware of the effect that the methods used to prepare their samples can have on the results. The accuracy of the results obtained using XRF largely depends on the properties of the samples, including the flatness, particle size, homogeneity, and thickness. These sample conditions for the reliable determination can be identified by the escape depth, i.e. analytical depth, of fluorescent X‐rays. This article describes the preparation of solid and powdered samples for use in XRF analysis in which the escape depth is taken into consideration. Studies in which loose powder, powder pellet, and glass bead specimens were prepared from such samples are then reviewed. The use of calibration curves derived using synthetic standards that have been prepared from chemical reagents containing analytes is also described, and studies in which analysis techniques based on calibration curves were evaluated using reference materials are also reviewed.
A methodology for incorporating a photon‐counting CT system into routine clinical use
Authors: Bache Steven T. , Samei Ehsan 
Published: June 2023

AbstractPhoton‐counting computed tomography (PCCT) systems are increasingly available in the U.S. following Food and Drug Administration (FDA) approval of the first clinical PCCT system in Fall 2021. Consequently, there will be a need to incorporate PCCTs into existing fleets of traditional CT systems. The commissioning process of a PCCT was devised by evaluating the degree of agreement between the performance of the PCCT and that of established clinical CT systems. A PCCT system (Siemens NAEOTOM Alpha) was evaluated using the American College of Radiology(ACR) CT phantom (Gammex 464). The phantom was scanned on the system and on a 3rd Generation EID CT system (Siemens Force) at three clinical dose levels. Images were reconstructed across the range of available reconstruction kernels and Iterative Reconstruction (IR) strengths. Two image quality metrics—spatial resolution and noise texture—were calculated using AAPM TG233 software (imQuest), as well as a dose metric to achieve target image noise magnitude of 10 HU. For each pair of EID‐PCCT kernel/IR strengths, the difference in metrics were calculated, weighted, and multiplied over all metrics to determine the concordance between systems. IR performance was characterized by comparing relative noise texture and reference dose as a function of IR strength for each system. In general, as kernel “sharpness” increased for each system, spatial resolution, noise spatial frequency, and reference dose increased. For a given kernel, EID reconstruction showed higher spatial resolution compared to PCCT in standard resolution mode. PCCT implementation of IR better preserved noise texture across all strengths compared to the EID, demonstrated by respective 20 and 7% shifts in noise texture from IR “Off” to IR “Max.” Overall, the closest match for a given EID reconstruction kernel/IR strength was identified as a PCCT kernel with “sharpness” increased by 1 step and IR strength increased by 1–2 steps. Substantial dose reduction potential of up to 70% was found when targeting a constant noise magnitude.