bluuebunny/crossref_metadata_2025_split huggingface dataset:
PGSOFuse-Net: PCA and GAN Integration for SAROptical Image Fusion
Authors: Bandi Sudheer Reddy , Murugesan Anbarasan , George Merlin Linda 
Published: September 2023

Abstract
To illustrate, radar images, popularly known as Synthetic Aperture Radar (SAR) and optical images are very useful in satellite-based information retrieval. But, the complementary nature of both these data led to misinterpretation of the information in various fields like military surveillance, weather forecasting, and resource management. However, the study of image fusion on optical SAR images has overcome some of the limitations in the remote sensing field with cloud removal, change detection, and infrastructure identification. There have been traditional approaches like wavelet analysis, cosine transform, and sparse representation in image fusion which were not more effective in analysing the nature of SAR and optical images. Hence, the advanced algorithms based on neural networks which are very much effective in image fusion, especially in medical diagnostics, social networks, and surveillance are used in the anticipated study. Recent studies of deep-learning-based approaches specifically Generative Adversarial Networks (GAN) architecture suggest decent developments in image fusion. With good developments in Principal Component Analysis for image compression, image segmentation, and image representation in satellite imagery, the suggested work develops a hybrid fusion model which is an innovative combination of Principal Component Analysis and GAN to produce the target image. The effectiveness of the proposed unsupervised algorithm improves the results and preserves the characteristics of both image types. The results specify the importance of the GAN in the SAR optical fusion with the proposed PCA GAN SAR Optical Fusion Network. Subsequently, the assessment of the quality metrics reveals that the current study outperforms prior works and is very useful for future geoinformation.
Foresight Plus: Scalable Serverless Real-Time Spatio-Temporal Traffic Forecasting
Authors: Oakley Joe , Conlan Chris , Demirci Gunduz Vehbi , Sfyridis Alexandros , Ferhatosmanoglu Hakan 
Published: September 2023

Abstract
Building a real-time, cost-effective, spatio-temporal forecasting system is a challenging problem with many practical applications such as traffic and road network management. Most forecasting research focuses on average prediction quality, with less attention paid to building practical pipelines and achieving timely and accurate forecasts when the network is under heavy load. Additionally, transport authorities need to leverage dynamic data sources (e.g., scheduled roadworks) and vehicle-level flow data, while also supporting ad-hoc inference workloads at low cost. The cloud-based system Foresight, developed in collaboration with Transport for the West Midlands (TfWM), is able to ingest, aggregate and process streamed traffic data, as well as dynamic urban events/flow data to produce regularly scheduled forecasts with high accuracy. In this work, we extend our system with several novel enhancements. First, we present an efficient method for extending the forecasting scale, enabling transport managers to predict traffic patterns further into the future than existing methods. In addition, we augment the existing inference architecture with a new, fully serverless design. This offers a more cost-effective inference solution, which seamlessly handles sporadic inference workloads over multiple forecasting models. We observe that Graph Neural Network (GNN) forecasting models are robust to extensions of the forecasting scale, achieving consistent (and sometimes even improved) performance up to 24 hours ahead. This is in contrast to the 1 hour forecasting horizons popularly considered in the literature. Further, our serverless inference solution is shown to be significantly more cost-effective than provisioned alternatives in appropriate use-cases. We identify the optimal memory configuration of serverless resources to achieve an attractive cost-to-performance ratio.
Grid cell firing patterns maintain their hexagonal firing patterns on a circular track
Authors: Hedrick Kathryn , Yim Manyi , Walton Steven 
Published: September 2023

Abstract
In an open two-dimensional environment, grid cells in the medial entorhinal cortex are known to be active in multiple locations, displaying a striking periodic hexagonal firing pattern covering the entire space. Both modeling and experimental data suggest that such periodic spatial representations may emerge from a continuous attractor network. According to this theory, grid cell activity in any stable 1D environment is a slice through an underlying 2D hexagonal pattern, which is supported by some experimental studies but challenged by others. Grid cells are believed to play a fundamental role in path integration, and so understanding their behavior in various environments is crucial for understanding the flow of information through the entorhinal-hippocampal system. To this end, we analyzed the activity of grid cells when rats traversed a circular track. A previous study involving this data set analyzed individual grid cell activity patterns separately, but we found that individual grid cells do not provide sufficient data for determining the underlying spatial activity pattern. To circumvent this, we compute the population autocorrelation, which pools together population responses from all grid cells within the same module. This novel approach recovers the underlying six-peak hexagonal pattern that was not observable in the individual autocorrelations. We also use the population autocorrelation to infer the spacing and orientation of the population lattice, revealing how the lattice differs across environments. Furthermore, the population autocorrelation of the linearized track reveals that at the level of the population, grid cells have an allocentric code for space. These results are strong support for the attractor network theory for grid cells, and our novel approach can be used to analyze grid cell activity in any undersampled environment.
Midbrain lesion-induced disconjugate gaze: a unifying circuit mechanism of ocular misalignment?
Authors: Friedrich Maximilian U. , Schappe Laurin , Prasad Sashank , Friedrich Helen , Fox Michael D. , Zwergal Andreas , Zee David S. , Faßbender Klaus , Dillmann Klaus-Ulrich 
Published: September 2023

Abstract
Background: Disconjugate eye movements play a crucial role in depth perception for frontal-eyed species. Midbrain lesions cause disconjugate eye movement deficits, such as skew deviation and hemi-seesaw nystagmus in the vertical plane or esodeviation and convergence-retraction nystagmus in the horizontal plane. While the former have been linked to defective visuo-vestibular interaction, the pathophysiology of the latter remains elusive.
Methods & Results: We report a patient with a solitary focal midbrain lesion, presenting with both vertically and horizontally disconjugate eye movement disorders. Videooculography showed a strong correlation of vertical and horizontal oscillations during fixation but not in darkness. Oscillation intensities and waveforms were modulated by fixation, illumination and gaze position, hinting at shared visual- and vestibular-related mechanisms. Diffusion MRI, combined with co-registration to a cytoarchitectonic MR-atlas, pinpointed the lesion to a functionally ill-defined area of the dorsal midbrain, adjacent to the posterior commissure and nuclei with known roles in vertical gaze control.
Conclusion: A circumscribed region in the dorsal midbrain is a key node for disconjugate eye movements across both vertical and horizontal planes. Lesioning this area produces a unique ocular motor syndrome that mirrors hallmark patterns of developmental strabismus. Further circuit-level studies could offer pivotal insights into shared pathomechanisms.
TreeML-Data; a multidisciplinary and multilayer urban tree dataset
Authors: Yazdi Hadi , Shu Qiguan , Rötzer Thomas , Petzold Frank , Ludwig Ferdinand 
Published: September 2023

Abstract

The significance of urban trees in promoting human health and well-being has been amplified by urbanization and the climate change effects. Simultaneously, advancements in remote sensing techniques have enhanced the opportunities for studying urban trees. The TreeML-Data has been compiled to support these efforts. It consists of labelled point clouds of 40 scanning projects of streets in Munich, 3,755 leaf-off point clouds of individual trees, quantitative structure models (QSM), tree structure measurements, and tree graph structure models of the trees in these streets. The dataset offers valuable data for generating and evaluating models in various scientific disciplines, which include remote sensing, computer vision, machine learning, urban forestry, urban ecosystem, green architecture, and graph analysis. To ensure its quality, the tree structure measurements and QSM have been crosschecked. For instance, the tree diameter at breast height (DBH) in the sample dataset exhibits a deviation of approximately 1.5 cm (4.3 %) when compared to manual measurements. In conclusion, the quality checks confirm its reliability for subsequent studies when compared to manual measurements.
Burrows buffer nest temperatures and offer a stable thermal microclimate for threatened seabird chicks during extreme events
Authors: Richards Cerren , Collins Sydney M. , Fisher Kayla , Blackmore Robert J. , Fifield David A. , Bates Amanda E. 
Published: September 2023

Abstract
Climate change is altering the severity and intensity of extreme weather events. Occupying microhabitats that buffer extreme weather may help species avoid harsh environmental conditions. Monitoring important habitats during extreme weather can highlight species that may benefit from targeted conservation actions. We describe the thermal microclimate and buffering capacity of Atlantic puffin (Fratercula arctica) and Leach’s storm-petrel (Hydrobates leucorhous) burrows during extreme events and test for correlation between weather conditions and burrow characteristics on nest microclimate and buffering capacity. Both species’ burrows buffered temperatures during extreme cold weather as nests were 7.4–8.0°C warmer than external temperatures. In extreme warm weather, Leach’s storm-petrel and Atlantic puffin burrows were 9.5°C and 5.4°C cooler than outside temperatures, respectively. External temperature and wind speed were strong drivers of burrow temperature. Thus, the buffering capacity varied depending on the specific extreme events. Moreover, smaller burrow volume and greater canopy cover improved burrow buffering capacity during extreme events. Our results suggest that burrows may provide a direct line of defence for seabird chicks against cold and warming events. Given the complex responses of burrow microclimates to extreme events, quantifying how changes in environmental conditions will impact burrow-nesting seabirds in the future is key.
Acute Lymphoblastic Leukemia With Surface Light Chain Expression
Authors: Bapat Kalyani , Mansukhani Dia , Khodaiji Shanaz , Almel Sachin 
Published: September 2023

Acute Lymphoblastic leukemias (ALL) are a heterogeneous group of neoplasms which can either be having precursor B cell immunophenotype or mature B cell immunophenotype. Surface immunoglobulin light chain restriction is usually a feature of mature B cell neoplasms. A precursor B cell lymphoblastic leukemia (pre-B-ALL) with surface immunoglobulin light chain expression is a rare immunophenotype . We report a case of a 4 year old female with L1 type of blast morphology yet showing surface light chain restriction. Recognizing this rare immunophenotype and arriving at a correct diagnosis has therapeutic implications as treatment regimens differ for precursor B ALL as compared to mature B cell neoplasms.
1960’lı Yıllarda Müzik Alanında Sendikal Bir Örgütlenme: Türk Müziği Sanatçıları Sendikası ve Müzik-iş Gazetesi (1968)
Authors: ÇETİN Esra 
Published: September 2023

İlk örnekleri İngiltere’de sanayi devriminin bir ürünü olarak ortaya çıkan sendikal hareketler, XIX. yüzyılda yaşanan siyasi ve iktisadi gelişmeler ile birlikte kapitalist üretim ilişkileri çerçevesinde işçilerin yardımlaşma ve dayanışma örgütleri olarak kurulmuştur. Türk sendikacılığı ise Osmanlı Devleti’nde bir sınıf hareketine bağlı olmaksızın XIX. yüzyıl sonu ve XX. yüzyıl başında oluşmaya başlamıştır. Cumhuriyet’in ilk yıllarında dönemin sosyal ve siyasi şartları nedeniyle istenen ölçüde ilerleme gösteremeyen sendikal hareketler, II. Dünya Savaşı sonrasındaki 1947-1950 arasındaki dönemde tekrar faal duruma geçmiştir. Daha sonra 1961 Anayasası ile sendikacılık alanında yeni düzenlemeler yapılmış, buna paralel olarak özellikle meslek örgütleri olarak kurulan sendika sayısı da artmıştır.
Bu sendikalardan biri olan Türk Müziği Sanatçıları Sendikası (Müzik-iş), 1965 yılının Ocak ayında yetmiş Türk müziği sanatçısı tarafından Ankara’da kurulmuştur. Türk-İş Konfederasyonu’na bağlı millî sendika statüsünde kurulan Müzik-iş, kurulduğu yıl İzmir ve İstanbul’da, 1966 yılında ise Gaziantep’te şube açmıştır. 1968 yılının Mart ayında ise sendikanın yayın organı olan Müzik-iş Gazetesi çıkarılmaya başlanmış ve yalnızca yedi sayı yayınlanmıştır. Bu çalışmada Türk sendikacılık tarihinde ilginç bir yeri olan Müzik-iş Sendikası incelenmiştir. Değerlendirme yapılırken sendikanın yayın organı Müzik-iş Gazetesinden yararlanılmıştır. Ayrıca Başbakanlık Osmanlı Arşivi, Başbakanlık Cumhuriyet Arşivi, Türkiye Büyük Millet Meclisi Zabıt Ceridelerinden, Resmî Gazete ve konuyla ilgili tetkik eserlerden de faydalanılmıştır.
Sustaining an elementary school-based hygiene intervention in Bangladesh by forming ‘hygiene committees’: a pilot study
Authors: Sultana Farhana , Khan Shaan Muberra , Rahman Mahbubur , Winch Peter J. , Luby Stephen P. , Unicomb Leanne 
Published: September 2023

AbstractSchool-based water, sanitation and hygiene (WASH) promotion often lacks strategies to sustain behaviors beyond the promotion period. This paper describes school community engagement, in the form of a hygiene committee to institutionalize a school-based hygiene intervention and its role in implementation and sustainability. With formative data on existing hygiene practices from four urban and rural elementary schools, we arranged a workshop to design a low cost, acceptable, and feasible hygiene intervention. We formed hygiene committees including student representatives in each of four additional schools, and piloted and assessed the hygiene intervention. The hygiene committee members' active role supported intervention facilities, materials and maintenance, and promoted targeted behaviors. They encouraged continued use of hygiene materials and provided funds to cover the cost of consumables. The teachers' commitment, student motivation, and financial cost recovery facilitated continued intervention activities. During the 14-months follow-up assessment, the hygiene committee activities were still in place in all schools. The dual involvement of teachers and students in hardware maintenance ensured hygiene intervention consumables availability, functionality, and retention in the pilot schools. The hygiene committee facilitated intervention implementation and sustained functionality. Future school interventions should consider this approach in the implementation processes and cost-recovery strategies.
Estrogen Sulfotransferase SULT1E1 Expression Levels and Regulated
Factors in Malignant Tumours
Authors: Wang Rui , Li Xia , Li Yangyang , Zhao Mengjie , Mi Lida , Chen Weiwei , Song Jianxiang 
Published: September 2023

Abstract:
Estrogen plays a key role in the development and progression of many malignant tumours,
and the regulation of estrogen levels involves several metabolic pathways. Among these
pathways, estrogen sulfotransferase (SULT1E1) is the enzyme with the most affinity for estrogen
and is primarily responsible for catalysing the metabolic reaction of estrogen sulphation. Relevant
studies have shown significant differences in the expression of SULT1E1 in different malignant tumours,
suggesting that SULT1E1 plays a dual role in malignant tumours, both inhibiting the
growth of malignant tumours and promoting their development. In addition, the expression level of
SULT1E1 may be regulated by a variety of factors, which in turn affect the growth and therapeutic
effects of malignant tumours. The aim of this paper is to review the mechanism of action of
SULT1E1 in malignant tumours and the mechanisms that are regulated, in order to provide potential
targets for the treatment of malignant tumour patients in the future and theoretical support for
the realisation of more personalised and effective therapeutic regimens.
The Role of Mesenchymal Stem/Stromal Cells Secretome in Macrophage
Polarization: Perspectives on Treating Inflammatory Diseases
Authors: Ti Dongdong , Yi Jun , Chen Huihua , Hao Haojie , Shi Chunmeng 
Published: September 2023

Abstract:
Mesenchymal stem/stromal cells (MSCs) have exhibited potential for treating multiple inflammation-
related diseases (IRDs) due to their easy acquisition, unique immunomodulatory and tissue
repair properties, and immune-privileged characteristics. It is worth mentioning that MSCs release a wide
array of soluble bioactive components in the secretome that modulate host innate and adaptive immune
responses and promote the resolution of inflammation. As the first line of defense, macrophages exist
throughout the entire inflammation process. They continuously switch their molecular phenotypes accompanied
by complementary functional regulation ranging from classically activated pro-inflammatory
M1-type (M1) to alternatively activated anti-inflammatory M2-type macrophages (M2). Recent studies
have shown that the active intercommunication between MSCs and macrophages is indispensable for the
immunomodulatory and regenerative behavior of MSCs in pharmacological cell therapy products. In this
review, we systematically summarized the emerging capacities and detailed the molecular mechanisms of
the MSC-derived secretome (MSC-SE) in immunomodulating macrophage polarization and preventing
excessive inflammation, providing novel insights into the clinical applications of MSC-based therapy in
IRD management.
Research Progress on the Anticancer Activity of Plant Polysaccharides
Authors: Liu Qiaoyan , Song Bo , Tong Sen , Yang Qiuqiong , Zhao Huanhuan , Guo Jia , Tian Xuexia , Chang Renjie , Wu Junzi 
Published: September 2023

Abstract:
Tumor is a serious threat to human health, with extremely high morbidity and mortality
rates. However, tumor treatment is challenging, and the development of antitumor drugs has always
been a significant research focus. Plant polysaccharides are known to possess various biological
activities. They have many pharmacological properties such as immunomodulation, antitumor,
antiviral, antioxidative, antithrombotic, and antiradiation effects, reduction of blood pressure
and blood sugar levels, and protection from liver injury. Among these effects, the antitumor
effect of plant polysaccharides has been widely studied. Plant polysaccharides can inhibit tumor
proliferation and growth by inhibiting tumor cell invasion and metastasis, inducing cell apoptosis,
affecting the cell cycle, and regulating the tumor microenvironment. They also have the characteristics
of safety, high efficiency, and low toxicity, which can alleviate, to a certain extent, the adverse
reactions caused by traditional tumor treatment methods such as surgery, radiotherapy, and
chemotherapy. Therefore, this paper systematically summarizes the direct antitumor effects of
plant polysaccharides, their regulatory effects on the tumor microenvironment, and intervening
many common high-incidence tumors in other ways. It also provides data support for the administration
of plant polysaccharides in modern tumor drug therapy, enabling the identification of new
targets and development of new drugs for tumor therapy.
The GDPR’s Rules on Data Breaches: Analysing Their Rationales and Effects
Authors: Borgesius Frederik Zuiderveen , Asghari Hadi , Bangma Noël , Hoepman Jaap-Henk 
Published: September 2023

The General Data Protection Regulation (GDPR) requires an organisation that suffers a data breach to notify the competent Data Protection Authority. The organisation must also inform the relevant individuals, when a data breach threatens their rights and freedoms. This paper focuses on the following question: given the goals of the GDPR’s data breach notification obligation, what are its strengths and weaknesses? We identify six goals of, or rationales for, the GDPR`s data breach notification obligation, and we assess the obligation in the light of those goals. We refer to insights from information security and economics, and present them in a reader-friendly way for lawyers. Our main conclusion is that the GDPR’s data breach rules are likely to contribute to the goals. For instance, the data breach notification obligation can nudge organisations towards better security; such an obligation enables regulators to perform their duties; and such an obligation improves transparency and accountability. However, the paper also warns that we should not have unrealistic expectations of the possibilities for people to protect their interests after a data breach notice. Likewise, we should not have high expectations of people switching to other service providers after receiving a data breach notification. Lastly, the paper calls for Data Protection Authorities to publish more information about reported data breaches. Such information can help to analyse security threats.
Historización del campo psicopedagógico en Patagonia Austral. UNPA
Authors: Oyarzo Camila Andrea 
Published: September 2023

El presente trabajo expone los avances del plan de tesis que se llevan a cabo en el marco del Doctorado en Ciencias Sociales y Humanidades. Busca indagar cómo se ha ido configurando y desarrollando el campo psicopedagógico a lo largo de la historia. A su vez, cómo se fue conformando y transformando la cultura profesional de dicho campo en el escenario socioinstitucional de la Patagonia Austral.
El análisis de documentos y las entrevistas desarrolladas hasta el momento nos permiten identificar diversos temas que contribuyen a la comprensión del objeto de estudio: realidad laboral, vivencias psicopedagógicas en pandemia, áreas de formación, trayectorias y plan de estudio.
La perspectiva teórica y metodológica adoptada contempla una posición teórica investigativa cualitativa puesto que prioriza la comprensión del fenómeno estudiado en la voz de los propios actores sociales. Recuperando desde sus narrativas cómo los sujetos asumen, conciben y viven la profesión psicopedagógica en el contexto de la Patagonia Austral, dando cuenta de los efectos sociales y subjetivos que provocan la inserción al campo profesional