bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of Petroleum Hydrocarbons in Soil from Auto-mobile Mechanic Workshops within Ikot Akpaden, Mkpat Enin L.G.A Akwa Ibom State Nigeria
Authors: Ikpe E. E. , Ubong U. U. , Uwanta E. , Oku U. U , Akpan E. O. 
Published: March 2023

This study investigates the concentrations of total petroleum hydrocarbon (TPH) and total hydrocarbon content (THC) in soil samples from auto-mobile mechanic workshop in Ikot Akpaden, Mkpat Enin. Soil samples were collected in triplicate at different points within the vicinity of auto-mobile mechanic workshop at Ikot Akpaden represented as site A and control samples were obtained within the frontage of Chemistry Department, AKSU represented as site C. Soxhlet extraction and shaking methods were used for the extraction of the total petroleum hydrocarbons and total hydrocarbon content respectively. Each of the sample extracts were purified using column chromatography to remove moisture, polar hydrocarbons, colour interferences and any impurities before GC analysis. Total petroleum hydrocarbons and THC were analyzed using Gas Chromatography (GC-FID) and UV-VISIBLE spectrophotometer respectively. The results obtained from TPH analysis indicates that; 15,223.4 mg/kg was recorded from the auto-mobile mechanic workshop and 808.507 mg/kg was recorded from the control samples. The results from the two stations were higher than the department of petroleum resources (DPR) permissible limit of 50 mg/Kg for soils. There was significant difference in the concentration of total hydrocarbon content, the result obtained showed that, the three sampling point at the mechanic workshop has THC level in the order; A1>A3>A2. The concentration of THC obtained in the three points were greater than the 0.6 mg/Kg limit of total hydrocarbons content allowed by the DPR. The study revealed that the soils were polluted as a result of indiscriminate disposal of waste petroleum products (used engine oil, petrol, diesel and other lubricants) directly on the soil, as well as dumping and burning of waste at the auto-mobile mechanic workshops. Hence, there is need for a holistic and sustainable monitoring and remediation of the environment for a cleaner and healthier environment.
Organic Amendments Addition on Altering the Sorption, Vertical Movement and Leaching Behavior of Herbicides in Soil
Authors: Janaki P. 
Published: March 2023

Herbicides are applied indiscriminately to achieve maximum weed control in agricultural production which might contaminate the food chain through the bio-augmentation of residue concentration in soil. One of the management suggested to overcome the herbicides contamination is treating with various organic amendments. Hence the laboratory column leaching and sorption experiments were conducted in Tamil Nadu Agricultural University (TNAU), Coimbatore to investigate the leaching behavior of herbicides viz., pendimethalin, atrazine and imazethapyr in soil as influenced by various organic amendments applied @ 5t/ha viz., FYM, vermicompost, composted coir pith, maize crop residue and biochar. Leaching experiment was conducted using PVC columns of 45 cm length and the sorption study was conducted using different concentrations of chosen herbicides as per OECD guidelines. Results showed that leaching and movement behavior of the studied herbicides in soil was modified by the applied organic amendments particularly the biochar and maize crop residue. Biochar treated soil retained 29.76, 40.20, and 38.07 percent of the applied pendimethalin, atrazine and imazethapyr respectively in surface 0-15 cm depth and reduced its movement to lower depths and to leachates. Herbicides adsorption was higher with biochar and is indicated by the Koc values of 225, 184 and 22 mg/L for pendimethalin, atrazine and imazethapyr respectively and was followed by the maize crop residue. It is concluded that the application of biochar @ 5t/ha as organic amendment is efficient in decreasing the herbicides movement viz., pendimethalin, atrazine and imazethapyr and modifying their sorption and leaching potential to groundwater.
Recent Advances of Material‐Decorated Photosynthetic Microorganisms and Their Aspects in Biomedical Applications
Authors: Liu Songhan , Yang Hanyu , Ho Ming Yao , Xing Bengang 
Published: March 2023

AbstractPhotosynthetic microorganisms, especially microalgae and cyanobacteria, have been well‐developed as attractive biomaterials with their eigen oxygen production capability, high‐value metabolites, and diverse biofunctionalities. Moreover, recent advances in nanotechnology and materials sciences also witnessed promising prospects by integrating unique properties of distinctive functional materials with photosynthetic microorganisms to construct material‐decorated photosynthetic microorganisms (MPMs) that can foster diversified biomedical functions. These integrated MPM hybrids can serve as smart cargoes for targeting therapeutic delivery, mainly due to their modifiable surface morphology, actuated propulsion, good biocompatibility, and spacious encapsulating effect. Moreover, attributing to the intrinsic oxygenation and autofluorescence, the MPMs can also act as the oxygen supplier to conduct various oxygen‐related modulation and image‐guided therapies. This review systematically outlines the recent advances of MPMs as unique platforms to achieve their targeted drug delivery. In addition, promising applications of these micro‐sized biohybrids for in situ oxygen modulation and oxygen‐related therapeutic manipulation are also summarized. Some relevant applications regarding their synergistic theranostics and the feasibility as the macro‐sized scaffold for tissue engineering and wound healing are also carefully covered. Finally, current challenges and future perspectives of these multifunctional material‐microbe hybridized conjugations are also discussed.
Electrospinning‐Driven Binary Oxide Nanofiber Networks with Tunable Amorphous Microstructure for Booming Transistors and Circuits Operation
Authors: He Bo , He Gang , Hu Qingqing , Jiang Shanshan , Gao Qian , Fortunato Elvira , Martins Rodrigo 
Published: March 2023

AbstractAlthough In2O3 nanofibers (NFs) are regarded as one of the active channel materials for next‐generation, low‐cost thin‐film transistors (TFTs), these NFs‐based devices still suffer from the degraded carrier mobility and operational instability, limiting the ability of such devices to replace current polycrystalline silicon technologies. Here, it is shown that nanofiber channel transistors with high electron mobility and operational stability can be achieved by selectively doping Zn element into electrospun In2O3 NFs. By precisely manipulating the doping level during NFs fabrication, their crystallinity, surface morphology, and corresponding device performance can be regulated reliably for enhanced transistor performances. It has been detected that InZnO/SiO2 TFTs with an optimized Zn doping concentration of 50% have demonstrated the high field‐effect mobility (µFE) of 6.38 cm2 V−1 s−1, the larger ION/IOFF of 4.12 × 107 and operation in the energy‐efficient enhancement‐mode. Low frequency noise (LFN) measurements have displayed that the scattering and defects inside the NFs are effectively suppressed by the particular microstructure. When integrating ALD‐derived Al2O3 films as the gate dielectric into TFTs devices, their electron mobility and ION/IOFF can be further improved to 37.82 cm2 V−1 s−1 and 2.92 × 108, respectively. To demonstrate the potential toward more complex logic applications, a low voltage resistor‐loaded unipolar inverter is built by using InZnO/Al2O3 TFT, exhibiting a high gain of 20.95 and full swing characteristics. These optimized parameters have demonstrated the significant advance of this electrospinning technique toward practical applications for high performance and large‐scale electronics.
A cryptic pathogenic NDUFV1 variant identified by RNA‐seq in a patient with normal complex I activity in muscle and transient magnetic resonance imaging changes
Authors: Kiss Sharmila , Christodoulou John , Thorburn David R. , Freeman Jeremy L. , Kornberg Andrew J. , Mandelstam Simone , Compton Alison G. , Cummings Beryl , Pais Lynn , Yaplito‐Lee Joy , White Susan M. 
Published: March 2023

AbstractMitochondrial respiratory chain disorders (MRC) are amongst the most common group of inborn errors of metabolism. MRC, of which complex I deficiency accounts for approximately a quarter, are very diverse, causing a wide range of clinical problems and can be difficult to diagnose. We report an illustrative MRC case whose diagnosis was elusive. Clinical signs included failure to thrive caused by recurrent vomiting, hypotonia and progressive loss of motor milestones. Initial brain imaging suggested Leigh syndrome but without expected diffusion restriction. Muscle respiratory chain enzymology was unremarkable. Whole‐genome sequencing identified a maternally inherited NDUFV1 missense variant [NM_007103.4 (NDUFV1):c.1157G > A; p.(Arg386His)] and a paternally inherited synonymous variant [NM_007103.4 (NDUFV1):c.1080G > A; (p.Ser360=)]. RNA sequencing demonstrated aberrant splicing. This case emphasizes the diagnostic odyssey of a patient in whom a confirmed diagnosis was elusive because of atypical features and normal muscle respiratory chain enzyme (RCE) activities, along with a synonymous variant, which are often filtered out from genomic analyses. It also illustrates the following points: (1) complete resolution of magnetic resonance imaging changes may be part of the picture in mitochondrial disease; (2) analysis for synonymous variants is important for undiagnosed patients; and (3) RNA‐seq is a powerful tool to demonstrate pathogenicity of putative splicing variants.
COL1A1 and COL1A2 variants in Ehlers‐Danlos syndrome phenotypes and COL1‐related overlap disorder
Authors: Venable Elise , Knight Dacre R. T. , Thoreson Emily K. , Baudhuin Linnea M. 
Published: March 2023

AbstractPathogenic variants in COL1A1 and COL1A2 are involved in osteogenesis imperfecta (OI) and, rarely, Ehlers‐Danlos syndrome (EDS) subtypes and OI‐EDS overlap syndromes (OIEDS1 and OIEDS2, respectively). Here we describe a cohort of 34 individuals with likely pathogenic and pathogenic variants in COL1A1 and COL1A2, 15 of whom have potential OIEDS1 (n = 5) or OIEDS2 (n = 10). A predominant OI phenotype and COL1A1 frameshift variants are present in 4/5 cases with potential OIEDS1. On the other hand, 9/10 potential OIEDS2 cases have a predominant EDS phenotype, including four with an initial diagnosis of hypermobile EDS (hEDS). An additional case with a predominant EDS phenotype had a COL1A1 arginine‐to‐cysteine variant that was originally misclassified as a variant of uncertain significance despite this type of variant being associated with classical EDS with vascular fragility. Vascular/arterial fragility was observed in 4/15 individuals (including one individual with an original diagnosis of hEDS), which underscores the unique clinical surveillance and management needs in these patients. In comparison to previously described OIEDS1/2, we observed differentiating features that should be considered to refine currently proposed criteria for genetic testing in OIEDS, which will be beneficial for diagnosis and management. Additionally, these results highlight the importance of gene‐specific knowledge for informed variant classification and point to a potential genetic resolution (COL1A2) for some cases of clinically diagnosed hEDS.
Variation in human functional eccrine gland density and its implications for the evolution of human sweating
Authors: Best Andrew W. , Lieberman Daniel E. , Gerson Alexander R. , Holt Brigitte M. , Kamilar Jason M. 
Published: March 2023

AbstractObjectivesWe aim to test three questions regarding human eccrine sweat gland density, which is highly derived yet poorly understood. First, is variation in functional eccrine gland density (“FED”) explained by childhood climate, suggesting phenotypic plasticity? Second, is variation in FED explained by genetic similarity (a proxy for “geographic ancestry”), implying divergent evolutionary pathways in this trait of ancestral populations? Third, what is the relationship between FED and sweat production?Materials and MethodsTo test questions one and two, we measured FED in 68 volunteers aged 18–39 with varied childhood climate regimes and geographic ancestries. To test question three, we compared sweat production to FED in our n = 68 sample. In addition, we examined the relationship between FED and whole‐body sweat loss during cycling in warm conditions using a sample of eight heat‐acclimated endurance athletes.ResultsInterindividual variation in six‐site FED was more than twofold, ranging from 60.9 to 132.7 glands/cm2. Variation in FED was best explained by body surface area and limb circumferences (negative associations) and poorly explained by childhood climatic conditions and genetic similarity. Pilocarpine‐induced sweat production was unrelated to FED while whole‐body sweat loss during cycling was significantly, though modestly, associated with FED.DiscussionWe hypothesize that gland‐level phenotypic plasticity, rather than changes in eccrine gland density, was sufficient to permit thermal adaptation to novel environments as humans colonized the globe. Future research should measure effects of FED in dehydrated states and the relationship between FED and salt loss, and control for effects of microclimate to rule out phenotypic plasticity effects.
Genetic propensity for cerebral amyloidosis and risk of mild cognitive impairment and Alzheimer's disease within a cognitive reserve framework
Authors: Mourtzi Niki , Charisis Sokratis , Tsapanou Angeliki , Ntanasi Eva , Hatzimanolis Alexandros , Ramirez Alfredo , Heilmann‐Heimbach Stefanie , Grenier‐Boley Benjamin , Lambert Jean‐Charles , Yannakoulia Mary , Kosmidis Mary , Dardiotis Efthimios , Hadjigeorgiou Georgiios , Sakka Paraskevi , Georgakis Marios , Yaakov Stern , Scarmeas Nikolaos 
Published: March 2023

AbstractINTRODUCTIONWe constructed a polygenic risk score (PRS) for β‐amyloid (PRSAβ42) to proxy AD pathology and investigated its association with incident Alzheimer's disease (AD)/amnestic mild cognitive impairment (aMCI) and the influence of cognitive reserve (CR), proxied by educational years, on the relationship between PRSAβ42 and AD/aMCI risk.METHODSA total of 618 cognitive‐normal participants were followed‐up for 2.92 years. The association of PRSAβ42 and CR with AD/aMCI incidence was examined with COX models. Then we examined the additive interaction between PRSAβ42 and CR and the CR effect across participants with different PRSAβ42 levels.RESULTSHigher PRSAβ42 and CR were associated with a 33.9% higher risk and 8.3% less risk for AD/aMCI, respectively. An additive interaction between PRSAβ42 and CR was observed. High CR was associated with 62.6% less risk of AD/aMCI incidence only in the high‐PRSAβ42 group.DISCUSSIONA super‐additive effect of PRSAβ42 and CR on AD/aMCI risk was observed. CR influence was evident in participants with high PRSAβ42.
Vacuum Rabi Splitting and Kerr Effect of a Hybrid Spin–Magnon–Photon System
Authors: Liao Qinghong , Qiu Haiyan , Zou Chen , Song Menglin 
Published: March 2023

AbstractThe vacuum Rabi splitting and Kerr effect are investigated theoretically in a hybrid spin–magnon–photon system, where the nitrogen‐vacancy center in diamond driven by two light fields is coupled to a spherical micromagnet embedded in a superconducting coplanar waveguide resonator. The results indicate that the phenomenon of the Mollow triplet and vacuum Rabi splitting can appear by controlling the spin–magnon coupling and magnon–photon coupling. It is shown that the probe absorption spectrum can be adjusted effectively via the pump frequency detuning. Moreover, it is demonstrated that the optical Kerr effect can be tuned by changing the Rabi frequency. This work may provide a possibility for the applications in quantum information processing and quantum sensing of magnetic signal.
Measurement‐Based Hyperentanglement Distillation for Lossy and Distortion Photon State
Authors: Wang Peng , Zhang Zheng , Yu Chang‐Qi , Yuan Rui‐Yang , Du Fang‐Fang , Ren Bao‐Cang 
Published: March 2023

AbstractThe information content of a photon system can be extended by hyperentanglement, but the quality of hyperentanglement will be decreased by the complicated transmission loss and channel noise in quantum information processing. Here, an efficient measurement‐based hyperentanglement distillation protocol (MB‐HDP) is presented for depressing the effects of complicated transmission loss and channel noise on hyperentanglement. In the MB‐HDP, the nonlocal lossy and distortion photon states are coupled to local hyperentangled Greenberger–Horne–Zeilinger (GHZ) states using parity measurement and qubit amplification device, and the decoherence caused by bit‐flip (phase‐flip) error, diverse transmission coefficients and transmission loss can be depressed by the successful measurement results, which can increase the quality of nonlocal hyperentangled photon state. This MB‐HDP broadens the application scope of hyperentanglement distillation to nonlocal lossy and distortion photon state with a lower degree of entanglement. In addition, the MB‐HDP can further improve the quality of nonlocal hyperentangled photon state by coupling multiple copies of lossy and distortion hyperentangled photon state with local hyperentangled GHZ states. This work demonstrates the ability of measurement‐based method for ensuring the quality of nonlocal hyperentanglement, which can improve the integrity and capacity of long‐distance quantum information processing.
Phytonutrient content and oil quality of selected edible oils upon twelve months storage
Authors: Teh Soek Sin , Lau Harrison Lik Nang 
Published: March 2023

AbstractEdible oils contain naturally occurring phytonutrients and therefore exhibit numerous beneficial health effects. However, the phytonutrients tend to degrade in different extent with storage duration and temperature. In this study, the impact of storage conditions on the stability of phytonutrients, including vitamin E, carotenoid, phytosterols and squalene, and oil quality, including free fatty acids (FFA), peroxide value (PV), anisidine value (AV), and oxidative stability index (OSI) of red palm‐pressed mesocarp olein, palm olein, extra virgin olive oil, and sunflower oil were investigated. The oils were stored in three conditions, 23°C (with light and without light) and 35°C (without light). Results showed that the retention percentages of phytonutrients where in the range of 0%–100% for vitamin E, 51.24%–83.63% for carotenoid, 83.40%–100% for phytosterols and 27.94%–100% for squalene. Pearson correlation analysis between phytonutrients and oil quality of oils in different storage conditions showed that correlation coefficient values (r) were in the range of −1 to 0 for FFA, −1 to 0.22 for PV, −1 to 0.33 for AV, and −0.23 to 1 for OSI, implying that correlations between both variables are not in same direction. Degradation studies of phytonutrients using zero‐order kinetic model where optimum‐case conditions exhibited highest half‐life (t1/2) among the three conditions. In conclusion, storage conditions and synergistic effect affected the phytonutrients stability in the oils and oil quality in different extent. In general, storage at ambient temperature and dark condition contributed to the best phytonutrients retention and oil quality.
Concise Synthesis of Molecular Hyperboloids by Oligomeric Macrocyclization of Octagonal Molecules
Authors: Ikemoto Koki , Nagata Daiya , Matsuno Taisuke , Isobe Hiroyuki 
Published: March 2023

AbstractMolecular hyperboloids were designed and synthesized. The synthesis was achieved by development of oligomeric macrocyclization of an octagonal molecule with a saddle shape. The saddle‐shaped molecule, that is, [8]cyclo‐meta‐phenylene ([8]CMP), was decorated with two linkers for the oligomeric macrocyclization and was synthetically assembled by Ni‐mediated Yamamoto coupling. Three congeners of the molecular hyperboloids (2mer‐4mer) were obtained, and 2mer and 3mer were subjected to X‐ray crystallographic analysis. Crystal structures revealed nanometer‐sized hyperboloidal structures with 96π and 144π electrons, which also possessed nanopores on the curved molecular structures. Structures of [8]CMP cores of the molecular hyperboloids were compared with those of saddle‐shaped phenine [8]circulene with a negative Gauss curvature to confirm their structural resemblance, which suggests further explorations of expanded networks of molecular hyperboloids.
Anticancer Screening of Ru(II) Photoredox Catalysts at Single Cancer Cell Level
Authors: Fan Zhongxian , Xie Jiaen , Kushwaha Rajesh , Liang Shaoxia , Li Wenqing , Mandal Arif Ali , Wei Li , Banerjee Samya , Huang Huaiyi 
Published: March 2023

AbstractThe rapid efflux of Pt‐based chemotherapeutics by cancer cells is one of the major causes of drug resistance in clinically available drugs. Therefore, both the high cellular uptake as well as adequate retention efficiency of an anticancer agent are important factors to overcome drug resistance. Unfortunately, rapid and efficient quantification of metallic drug concentration in individual cancer cells still remains a tricky problem. Herein, with the help of newly developed single cell inductively coupled plasma mass spectrometry (SC‐ICP‐MS), we have found that the well‐known Ru(II)‐based complex, Ru3, displayed remarkable intracellular uptake and retention efficiency in every single cancer cell with high photocatalytic therapeutic activity to overcome cisplatin resistance. Moreover, Ru3 has shown sensational photocatalytic anticancer properties with excellent in‐vitro and in‐vivo biocompatibility under light exposure.
Fully distributed optimization of second‐order systems with disturbances based on event‐triggered control
Authors: Xu Mengyang , Li Mingxing , Hao Fei 
Published: March 2023

AbstractThis paper studies the distributed optimization problem of second‐order multiagent systems containing external disturbances. To reject the external disturbances and lead agents' states to converge to the optimal consensus point, an adaptive event‐triggered controller is proposed based on the internal model principle. With the adaptive mechanism, both the controller and the event‐triggering condition do not contain the parameters related to global information, such as the maximum Lipschitz constant and the minimum strongly convex constant of local cost functions, and hence the event‐triggered controller is fully distributed. By utilizing the event‐triggered scheme, the consumption of communication among neighbors and the computing resources are saved. Furthermore, with the Lyapunov analysis framework, the optimal consensus can be proved to achieve and Zeno behavior is excluded from the event‐triggering condition. Finally, the effectiveness of the proposed protocol is verified by numerical simulations.