bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intention-reflected predictive display for operability improvement of time-delayed teleoperation system
Authors: Zhu Yaonan , Fusano Keisuke , Aoyama Tadayoshi , Hasegawa Yasuhisa 
Published: July 2023

AbstractRobotic teleoperation is highly valued for its ability to remotely execute tasks that demand sophisticated human decision-making or that are intended to be carried out by human operators from a distance. However, when using the internet as a communication framework for teleoperation, high latency, and fluctuations make accurate positioning and time-dependent tasks difficult. To mitigate the negative effects of time delay, this paper proposes a teleoperation system that uses cross reality (XR) as a predictive display of the outcome of operators’ intended actions and develops a time-delay aware shared control to fulfill the intention. The system targets a liquid pouring task, wherein a white ring that indicates the intended height of the liquid surface is overlayed onto the beaker in a delayed camera image to close the visual feedback loop on the leader side. Simultaneously, the shared control automatically completes the pouring action to track the intended liquid height. The performance of the proposed system is validated based on liquid pouring experiments performed by human subjects. When compared with direct control, the absolute error rate decreased significantly for a constant round-trip time delay of 0.8 s and 1.2 s, similarly for a time-varying delay of 0.4 s and 0.8 s. Moreover, when the time-varying delay was 0.8 s, operators achieved significantly higher accuracy while maintaining comparable operation time. These results indicate that our proposed system improves operability even in the presence of time-varying delays in communication networks.
Coffee intake and hypertension in Korean adults: results from KNHANES 2012–2016
Authors: Shah Surabhi , Cho In-Jeong , Lee Whanhee , Pyun Wook Bum , Ha Eunhee 
Published: July 2023

Abstract
Background
Coffee is the most popular and widely consumed drink in the world. Coffee consumption seems to have both benefits and risk with respect to hypertension; results from studies evaluating effect of frequency of coffee consumption on risk of hypertension are mixed and inconsistent. Hence, we investigated the association of coffee consumption and hypertension in Korean adults.

Methods
Data from Korean National Health and Nutrition Examination Survey (KNHANES) 2012–2016 was obtained and 12,133 eligible participants were selected. The coffee consumption was attained using a food frequency questionnaire. Subsequently coffee intake was grouped into two categories: ≤2 and > 2 servings per day. Hypertension status was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, use of antihypertensive drug treatment, or both. Multivariable logistic regression analysis was used to examine the association of coffee consumption and hypertension.

Results
Logistic regression analysis showed that consumption of more than two servings of coffee a day was inversely associated with hypertension with odds ratio (OR) 0.84 (95% confidence interval [CI], 0.73–0.99). Similar results were seen in the propensity score-matched analysis (OR, 0.83; 95% CI, 0.69–0.98). Adults having age more than median value (OR, 0.76; 95% CI, 0.65–0.89) and normal cholesterol (OR, 0.84; 95% CI, 0.70–0.99) had significantly inverse association with hypertension, when coffee consumption was more than two servings daily.

Conclusions
More than two servings of coffee intake per day was inversely associated with hypertension as compared to consumption of ≤ 2 servings coffee per day.
Quantitative measurement of empathy and analysis of its correlation to clinical factors in korean patients with chronic diseases
Authors: Heo Ran , Shin Jinho , Kim Byung Sik , Kim Hyun-Jin , Park Kye-Yeung , Park Hoon-Ki , Kim Yu Mi , Hwang Seon Young , Mercer Stewart W. 
Published: July 2023

Abstract
Background
Empathy is the core of the physician-patient relationship. The Consultation and Relational Empathy (CARE) measure is a useful tool for assessing patient-rated empathy. There have been scarce data on empathy in chronic disease patients in Korea. We aim to evaluate empathy using the Korean CARE measure in patients from various clinical environments and the factors influencing the degree of empathy in patients with chronic disease.

Methods
Data were collected from patients with chronic diseases. Patients were from primary, secondary, and tertiary clinics. Characteristics of the patients, physicians, and disease status were collected. The difference in CARE score was studied according to the clinical factors.

Results
A total of 162 patients with chronic diseases were included. About 60% of patients were male. The mean age was 62 years. They had an average number of 2.6 diseases. More than half of patients experienced overt cardiovascular disease. About half of them had a history of hospitalization due to cardiovascular disease. The overall average CARE score was 45.6 ± 7.0. The CARE score was not significantly different according to the characteristics of the patient, physician, or disease status. Regarding marital status, the CARE score was significantly lower for the small number of patients (n = 4, 2.5%) who refused to provide their marital status than for other groups. Except for four patients, there was no significant difference in the CARE score among married, unmarried, or divorced groups. This trend was maintained in hypertensive patients.

Conclusions
The Korean CARE measure could assess patient-rated empathy in various clinical practices. The empathy of patients was high regardless of multiple factors.
Acquired laryngomalacia as a cause of post-extubation stridor and extubation failure following craniotomy: a case report
Authors: Mizunoya Kazuyuki , Onodera Keisyu , Takahashi Yuki , Toki Takayuki , Saito Hitoshi , Morimoto Yuji 
Published: July 2023

Abstract
Background
Laryngomalacia is a dynamic airway condition characterized by flaccid laryngeal tissue and inward collapse of supraglottic structures during inspiration. Although it may cause airway obstruction and requires careful management, there have been few reports regarding laryngomalacia after surgery. We report a case of adult-onset laryngomalacia occurred after craniotomy requiring reintubation.

Case presentation
A 21-year-old man was admitted to the ICU after craniotomy for a cerebellopontine angle tumor. He developed severe stridor immediately after extubation on the postoperative day 2 and required reintubation. On the postoperative day 5, similar episode occurred following re-extubation and fiberoptic laryngoscopy revealed a collapsed epiglottis and left arytenoid into the glottis. A diagnosis of laryngomalacia was made, and he underwent tracheostomy. Laryngomalacia had completely improved; however, bilateral vocal cord paralysis was detected 2 weeks later.

Conclusions
Acquired laryngomalacia should be considered as a possible mechanism of the airway symptoms in a patient with neurological dysfunction.
The ViaHole technique: a novel approach for recanalizing major side branch occluded by Viabahn stent-graft
Authors: Haraguchi Takuya , Tsujimoto Masanaga , Otake Ryo , Kashima Yoshifumi , Sato Katsuhiko , Fujita Tsutomu 
Published: July 2023

Abstract
Introduction
In managing arterial rupture, stent-graft implantation may cause limb ischemia by crossing a major branch for hemostasis. The ViaHole technique could circumvent a major branch occlusion.

Materials and methods
The process involved advancing retrograde devices into an occluded major branch by the stent-graft implantation to reach the outer surface of the stent-graft, puncturing the stent-graft with a 20-gauge needle to touch the retrograde device, manipulating the guidewire through the needle hole and externalizing it, advancing the microcatheter into the proximal lumen, catching the microcatheter using an antegrade 4-Fr catheter, inserting an antegrade guidewire into the retrograde microcatheter to cross the stent-graft hole, dilating the lesion and stent-graft hole using a 3.0-mm balloon, and ensuring hemostasis at the puncture site.

Results
A 72-year-old male with a history of stent-grafted treatment for right popliteal aneurysm presented with acute limb ischemia (ALI). The occlusion spanned distal superficial femoral artery to the below-the-knee arteries. Hemostasis was achieved after an unintentional rupture of the proximal posterior tibial artery during surgical thrombectomy by implanting endoluminal stent-grafts instead of surgical bypass due to no distal anastomosis site. However, recurrent ALI occurred three months later. Surgical bypass was again deemed unfeasible due to no run-off. Unsuccessful recanalization attempts of the bilateral tibial arteries led us to perform the ViaHole technique to recanalize the peroneal artery occlusion. Finally. successful revascularization was achieved, and 1-year patency was confirmed.

Conclusions
The ViaHole technique may be valuable for revascularizing a major side branch occluded by stent-graft implantation.
A computational analysis reveals eight novel high-risk single nucleotide variants of human tumor suppressor LHPP gene
Authors: Feroz Tasmiah , Islam Md. Kobirul 
Published: July 2023

Abstract
Background
LHPP is a tumor suppressor protein associated with various malignancies like liver, oral, pharyngeal, bladder, cervical, and gastric cancers through controlling various pathways. Several single nucleotide variants have been reported to cause cancers. The main objectives of our study were to investigate the impact of the deleterious non-synonymous single nucleotide variants on structure and functions of the LHPP protein.

Results
We used nine computational tools (SNAP2, PROVEAN, POLYPHEN 2, PREDICT SNP, MAPP, PhD-SNP, SIFT, PANTHER, and PMUT) to find out the deleterious SNPs. These nine computational algorithms predicted 34 nsSNPs to be deleterious as a result of their computational analysis. Using ConSurf, I-Mutant, SDM, MUpro, and Mutpred, we emphasized more how those harmful nsSNPs negatively affect the structure and function of the LHPP protein. Furthermore, we predicted the mutant protein structures and assessed the total energy value deviation in comparison with LHPP original structure and also calculated RMSD values and TM scores. By comparing the result from all these computational approaches, we shortlisted a total eight novel nsSNPs (D214G, D219N, Q224P, L231P, G236W, R234C, R234P, and V233G) that impose high risks to the structure and functions of LHPP protein. To analyze the mutant protein’s behavior in physiological condition, we performed 50 ns molecular dynamic simulation using WebGro online tool and found that the mutants values vary from the wild type in terms of RMSD, RMSF, Rg, SASA, and H-bond numbers. Prognostic significance analysis by Kaplan–Meier plotter showed that abnormal regulation of LHPP can also serve as a prognostic marker for the patient with breast, ovarian, and gastric cancers. Additionally, ligand binding sites analysis revealed the presence of D214G and D219N mutants in the binding site one which means these two nsSNPs can disturb the binding capacity of the LHPP protein. Protein–protein interaction analysis revealed LHPP proteins’ interactions with PPA1, ATP12A, ATP4A, ATP4B, ATP5F1, ATP5J, PPA2, ATP6V0A4, ATP6V0A2, and MT-ATP8 with different degree of connectivity.

Conclusion
These results demonstrate a computational understanding of the harmful effect of nsSNPs in LHPP, which may be useful for molecular approaches.
Liver stiffness, hepatorenal index, and microRNA-130b as predictors for chronic kidney disease in patients with non-alcoholic fatty liver disease
Authors: Hassafy Mohamed Yosef El , Elhadidi Abeer Shawky , Tahoon Mona Mostafa , Hemimi Eman El-Dawi , Lashen Sameh Aldesoky 
Published: July 2023

Abstract
Background and aim
Currently, nonalcoholic liver disease (NAFLD) is the most predominant chronic liver disorder. NAFLD has been linked to hepatic and extrahepatic morbidities. We aimed to investigate the role of acoustic radiation force impulse (ARFI), hepatorenal index (HRI), and serum microRNA-130b as non-invasive predictors for chronic kidney disease (CKD) in NAFLD patients.

Material and methods
In a case–control design, we included 40 NAFLD patients (20 NAFLD with CKD and 20 NAFLD without CKD) and 20 healthy controls. After clinical evaluation, laboratory assessments including liver test profile, renal function test, and quantification of microRNA-130b were done. Liver steatosis and stiffness were evaluated using HRI and ARFI.

Results
HRI and ARFI readings were significantly higher among NAFLD with CKD patients compared to other groups (P < 0.001). The median values of microRNA-130b were 32.1, 27.01, and 25.36 copies/µl in NAFLD with CKD, NAFLD without CKD, and healthy controls, respectively, with significant differences between groups (P < 0.05). ARFI values and HRI were positively correlated with microRNA-130b (P < 0.05). At a cutoff value > 28.13 copies/µl, microRNA-130b could differentiate between “NAFLD with CKD” and “NAFLD without CKD” patients with a sensitivity and specificity of 75% and 70%, respectively (AUC = 71.9%, P = 0.018).

Conclusions
Serum microRNA-130b, HRI, and ARFI are valuable noninvasive markers for the assessment of NAFLD. MicroRNA-130b is suggested as a sensitive biomarker for the prediction of CKD among NAFLD patients with good sensitivity and specificity.
Pattern of dyslipidemia and associated factors in coronary artery disease patients in Khyber Pakhtunkhwa: A cross-sectional secondary data analysis
Authors: Hussain Arif , Muhammad Zakria , Ali Iftikhar , Tariq Shafiq Ahmad , Hussain Arshad , Siraj Sami 
Published: July 2023

Objectives: To assess the prevalence, pattern, and associated factors of dyslipidemia in patients with coronary artery disease (CAD) in the Northwest region of Pakistan.
Method: A cross-sectional secondary data analysis was performed on CAD patients visiting cardiology clinics in selected hospitals from July to December 2019. A total of 362 patients were included via consecutive sampling. Dyslipidemia was operationalized according to the “National Cholesterol Education Program (NCEP ATP III) guidelines”.
Results: Mixed dyslipidemia was recorded in 92.26% of the patients, while isolated dyslipidemia was observed in 5.24%. A high prevalence of combined dyslipidemia with increased LDL-C, TG, and low HDL-C was noted. Contrarily, elevated LDL-C was the commonest single lipid disorder (84.25%). Hypercholesterolemia was the least common disorder. Increasing BMI was found to be independently associated with hypercholesterolemia (OR: 1.19). Similarly, age (OR: 0.97) and being a rural resident (OR: 2.61) were independent factors associated with hypertriglyceridemia. Furthermore, being an urban resident (OR: 2.25) and increasing BMI (OR: 1.77) were also significantly associated with high LDL-C.
Conclusion: Mixed dyslipidemias were observed in the majority of the patients. Age, BMI, and residence were noted to be independently associated with abnormal lipids. Early screening and proper management should be encouraged to minimize this significant cardiovascular risk.
doi: https://doi.org/10.12669/pjms.39.5.7382
How to cite this: Hussain A, Zakria M, Ali I, Tariq SA, Hussain A, Siraj S. Pattern of dyslipidemia and associated factors in coronary artery disease patients in Khyber Pakhtunkhwa: A cross-sectional secondary data analysis. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.7382
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Prediction model using risk factors associated with anastomotic leakage after minimally invasive esophagectomy
Authors: Su Peng , Huang Chao , Lv Huilai , Zhang Zhen , Tian Ziqiang 
Published: July 2023

Objective: To explore the risk factors of anastomotic leakage after minimally invasive esophagectomy (MIE) and to build a prediction model of the probability of postoperative anastomotic leakage.
Methods: Clinical data of patients undergoing MIE, admitted in the Fourth Hospital of Hebei Medical University from March 2018 to March 2022, were retrospectively selected, and risk factors of anastomotic leakage after MIE were analyzed by univariate and multivariate logistic regression. A prediction nomogram model was established based on the independent risk factors, and its prediction effect was evaluated.
Results: A total of 308 patients were included. Thirty patients had postoperative anastomotic leakage, with an incidence of 9.74%. Logistic regression analysis showed that age, postoperative delirium, pleural adhesion, postoperative pulmonary complications, high postoperative white blood cell count and low lymphocyte count were risk factors for postoperative anastomotic leakage. A nomograph prediction model was constructed based on these risk factors. The predicted probability of occurrence of the nomograph model was consistent with the actual probability of occurrence. The calculated C-index value (Bootstrap method) was 0.9609, indicating that the nomograph prediction model had a good discrimination ability. By drawing the receiver operating characteristic (ROC) curve, we showed that the area under the curve (AUC) of the nomograph prediction model was 0.9609 (95%CI: 0.937-0.985), which indicated a good prediction efficiency of the model.
Conclusions: The nomograph prediction model based on the independent risk factors of anastomotic leakage after MIE can accurately predict the probability of postoperative anastomotic leakage.
doi: https://doi.org/10.12669/pjms.39.5.8050
How to cite this: Su P, Huang C, Lv H, Zhang Z, Tian Z. Prediction model using risk factors associated with anastomotic leakage after minimally invasive esophagectomy. Pak J Med Sci. 2023;39(5):---------. doi: https://doi.org/10.12669/pjms.39.5.8050
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The Estimation of Fracture Intensity and Pressure Distribution using Analysis of Shear Wave Splitting on “Landak” Geothermal Field
Authors: Al Thariqsyah Muhammad , Ramadhan Irvan , Sudarmaji Sudarmaji 
Published: July 2023

<p><em>Shear wave splitting is a study that utilizes the differences between arrival times of two shear waves (slow and fast) propagating from a source to a receiver to identify the magnitude of the anisotropic medium through which they propagate. Aside from generating a delay time between two shear waves, the anisotropic medium also shifts the polarization of fast shear wave from its initial polarization which is indicated as the main orientation of the related fracture system. The study was conducted on Landak Field, located around Bukit Besar mountain range by analyzing provided data from December 2011 to April 2012. The results of this study show that the polarizations of fast shear waves in several stations are as following; NE-SW orientation at station R09, R17, R25, and R26, N-S orientation at station R08, and NW-SE orientation at station R17. Not only do these orientations of polarization show a good correlation with structural analysis in this area, but also important to be noted that all microseismic stations encounter a wide-spreading polarization phenomenon as an effect of complex anisotropy. The delay time from all stations ranges from 0.03 to 0.07 seconds. The normalization between delay time and length of ray path for all stations results in a fracture intensity parameter ranging from 0.004 to 0.011 seconds/km. This intensity is measured in slowness parameters, which shows increased value towards the Bukit Besar area, which potentially becomes the upflow zone of the geothermal system</em>. The study shows that the distribution of fracture intensity and pressure have correlation and identical trend with temperature distribution.</p>
A Brief Study of Methods to Determine the Electrical Resistivity of Materials
Authors: Khalid Inzamam 
Published: July 2023

<p class="Abstract">Present study deals with the study of methods to calculate the resistivity of materials. Different methods are discussed which determine the resistivity of specific materials on the basis of their shapes and sizes. Their working, structure, advantages and loopholes are discussed in a brief manner. Materials are categorized according to their magnitude of resistivity. The two probe method is helpful in measuring the resistivity of high resistive samples while four probe methods can be used for materials with low resistance. Pulse probe method measures the resistivity of materials having small physical dimensions. The Montgomery method is useful in finding the individual resistivities of anisotropic materials.</p>
Au piano et dans les starting blocks
Authors: Decout Maxime 
Published: July 2023

Abstract: L’œuvre d’Echenoz est une œuvre dynamique, dans laquelle les personnages sont souvent en mouvement. Deux représentants de ce rapport au geste, au déplacement et au corps retiendront l’attention : le musicien et le sportif. Echenoz leur a consacré trois livres au statut différent : Au piano , Ravel et Courir . S’il écrire la course à pied invite à se pencher sur la gestuelle du sportif, écrire la musique, par nature immatérielle, incite plutôt à l’aborder à partir des dimensions affectives ou harmoniques qui lui sont attachées. Mais Au piano et Ravel s’attaquent à la musique en tant qu’activité physique . C’est le musicien qui nous met en contact avec son art, ce qui le rapproche étonnamment du sportif. D’autant que ce dernier est lui aussi considéré comme un artiste. Tous deux pratiquent un art qui tient de l’excellence et de l’exception. Et celui-ci ne passe par des mots mais par des gestes, qui imposent de les décrypter à partir d’une archéologie mettant en lumière la façon dont ils relèvent d’une sémiologie, de scénographies, voire de mythologies telles que Barthes les a étudiées.