bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphological characterization using nonmetric variables in exotic oat (Avena SP.) accessions
Authors: belsariya Neha , Sahu Mayuri , Kak Anjali , Roy Sujit 
Published: March 2023

Abstract
Oat (Avena sativa L.) ranked 6th in the world cereal production which is an important annual crop of rabi season. The genus Avena is very large and diverse and includes diploid, tetraploid and hexaploid species (Kaur and Kapoor, 2017). Genus Avena includes 70 species, most of the oat’s production in worldwide belongs to the hexaploid species: Avena sativa L. (widely cultivated white oat) (2n = 6x = 42. AACCDD) and Avena byzantina C. Koch (red oats) (2n = 6x = 42. AACCDD). Other minor cultivated species includes Avena abyssinica (Ethiopian Oats) (2n = 4x = 28, AABB) and Avena strigosa (Known by Black Oats) (2n = 2x = 14, AsAs) (Gorash et.al., 2017). There is tremendous variability available in oat germplasm studied to characterize and evaluate the exotic genotypes excluding checks using DUS guidelines of different nonmetric traits. Two ninety-four oat genotypes belonging to ten different Avena species procured from NBPGR were characterized on the basis of observations recorded for eight morphological non-metric characters as per the guidelines for the conduct of test for Distinctiveness, Uniformity and Stability. The observations were recorded on five randomly selected plants in each genotype for the following thirteen non-metric traits viz., Early plant vigour, growth habit, leaf colour, leaf sheath pubescence, flag leaf attitude, Panicle attitude, awn per spikelet, seed colour, stem solidness, primary floret pubescence, spikelet shattering, hullness and biotic stress susceptibility at Research cum Instructional Farm, IGKV, Department of Genetics & Plant Breeding, Raipur during Rabi 2019-20. Coefficient of variation and principal component analysis revealed variability among the genotypes for the non-metric traits evaluated. Highly Significant positive correlation showed among traits viz., seed colour (black) and biotic stress susceptibility (very low). PCA analysis showed that genotypes namely EC0004456, EC0099165, EC0178761, EC0104007, EC0537811 were very different from each other. Cluster analysis separated genotypes into four sub cluster: genotype EC0022023 with erect flag leaf attitude and brown seed colour (Avena sativa) present in different cluster and 23 genotypes with brown seed present in one cluster, all belongs to Avena sativa only one genotype IC0282934 belongs to Avena byzantina. Genotype namely EC0108477, EC0039402, EC0039915 (Avena sterilis) showed black seed. The genotype EC0178761 having compact panicle attitude. stem solidness, primary floret pubescence, spikelet shattering, hullness shows only one class.
Post-traumatic responses to workplace violence among nursing professionals: A collaborative and comparative study in South Korea and Hong Kong
Authors: Hong Soyun , Nam Sujin , Wong Janet Yuen Ha , Kim Heejung 
Published: March 2023

Abstract
Background
Workplace violence has had a significant and negative psychological impact on nursing professionals worldwide. Concerted efforts worldwide to improve work environments have not yet removed nursing professionals from the threat of violence in East Asia. This study aimed to examine the differences in the rate, associated factors, and post-traumatic responses to workplace violence between South Korean nurses and Chinese nurses in Hong Kong among East Asian countries.
Methods
A cross-sectional, correlational study design recruited a total of 471 nurses (319 South Korean nurses and 152 Chinese nurses in Hong Kong) at online communities in South Korea and Hong Kong. The data were collected by conducting a Qualtrics survey from January 15, 2020, to July 24, 2021. A structured questionnaire was administered for data collection, including rate of workplace violence, perception of workplace violence, attitudes toward workplace violence, coping styles, post-traumatic cognitions, post-traumatic stress disorder, post-traumatic growth, and mental health indicators (depression, anxiety, and stress). T-test, chi-squared, and binary logistic regression analyses were conducted using SPSS version 25.
Results
In our sample, 30.7% South Korean nurses and 31.6% Chinese nurses in Hong Kong had experienced workplace violence. South Korean nurses and Chinese nurses in Hong Kong with experience of workplace violence had lower perceptions of it. Nurses with experience of workplace violence reported lower levels of mental health, and this trend was more prominent among South Korean nurses.
Conclusions
Our study findings showed a positive association between workplace violence and post-traumatic responses in both settings. We found that the close monitoring of post-traumatic responses associated with workplace violence could be improved by enhancing the nurses’ perception of workplace violence.
The endoscopic retrograde appendicitis therapy for acute appendicitis in children: a systematic review and meta-analysis
Authors: Liu Lan , Zeng Huiping , Fang Yifan , Zhang Bing , Yang Yingying , Bai Jianxi , Lin Sheng , Xie Siqi 
Published: March 2023

Abstract
Background:Acute appendicitis (AA) is one of the most common abdominal emergencies in children. There has been an increasing interest in endoscopic retrograde appendicitis treatment (ERAT) in the past twenty years. We performed a meta-analysis of ERAT for AA in children through a survey and an extensive literature search that summarized the clinical features and therapeutic efficacy of ERAT.
Methods: A systematic review and meta-analysis of retrospective studies published in PUBMED, MEDLINE, Cochrane, China National Knowledge Infrastructure (CNKI), WanFang and VIP Database. The search has a limit on date from Jan 1, 2012 to Jun 31, 2022, with the last search done on Oct 31, 2022. No publication restrictions or study design filters were applied. The registration number in PROSPERO was CRD42022377739.
Results: Seven retrospective cohort studies with 423 patients were enrolled in our study. In our study, almost 57.6% (95% confidence interval (CI) 52.8%-62.4%) of children who underwent ERAT were male, the pooled rate of successful intubation was 99.5%(95%CI 98.2%-100.0%), the average time of an ERAT is approximately 49 minutes(95% CI 48.179,49.833), and efficiency of ERAT for acute appendicitis was 99.0% (95% CI 96.5%-100.0%), while, the pooled rate of recurrence was 4.2% (95% CI 2.2%-6.7%), the mean time of hospital stays was 4.319 (95% CI 4.254-4.385) days probably, and occurrence of postoperative complication was about 3.9% (95% CI 2.0%-6.2%).
Conclusions: Our results testify the relevant morbidity, clinical characteristics and prognosis in the ERAT, in spite of an enormous heterogeneity among few primary studies. ERAT has high efficiency and low recurrence rate in children with acute uncomplicated appendicitis, and preserves the physiological function of the appendix and avoids sizeabledamage, so it can be a safe and effective treatment for appendicitis in children.
Integrated health care systems for asthma: A qualitative narrative study from the perspective of Ecuadorian health professionals
Authors: Granadillo Emily , Romero-Sandoval Adriana , Cisneros-Caceres María José , Montalvo-Yépez José Alfonso , Gómez-Urrego Juan Guillermo , Rodriguez-Alvarado Alejandro , Bachmann Max , Cruz Alvaro , Cooper Philip , Silva María Rejane Ferreira da , Romero-Sandoval Natalia 
Published: March 2023

Abstract
Background: Care coordination is a characteristic of integrated health service networks, understood as an action that, based on primary care, integrates the different levels of care. Care coordination can improve the quality of care, especially for chronic diseases such as asthma.
Objective: To analyse perspectives of health professionals within different levels of care on the care coordination for asthma in Ecuador.
Methods: Descriptive qualitative study. Guided by the Integrated Health Care Network Model, we completed 25 in-depth semi-structured interviews in three Ecuadorian cities between 2020 and 2021. Using purposive sampling, health care professionals were selected from primary, emergency, specialist, and managerial levels. We used narrative analysis to identify significant phrases from interviews. We followed the Standards for Reporting Qualitative Research.
Results: Participants highlighted the scarce use of institutional documents for the referral of patients with asthma from the first level to specialists and vice versa, as well as between the different health subsystems. They identified weaknesses in the follow-up for patients with asthma, lack of objectives shared between the different levels of care, duplication of tests and medical prescriptions, and lack of availability of appointments in the public system that limits access to specialized care. The managers highlighted the system's inability to assign appointments on time and failures in administrative processes for follow-up. Emergency professionals do not have access to previous clinical data for patients having an asthma attack, so they rely on the use of emergency treatments without scheduling a specialist referral afterwards.
Conclusions: From the perspectives of health professionals in Ecuador, asthma care coordination requires strengthening at all levels within the public health system, from the formulation of common goals to improved transfer of asthmatic patients between levels to optimize healthcare resources.
Intelligent situation awareness based on the fractal dimension and multidimensional reconstruction
Authors: Wang Peiyuan , Guan Xin 
Published: March 2023

Abstract
In order to realize autonomy and intelligence for situation awareness, this paper proposes an intelligent situation awareness model based on fractional dimension information mining and multi-dimensional information reconstruction. First, the spatial situation perception is established by 3D reconstruction of the input fusion information, 4D completes the situation comprehension and 5D reconstruction seeks the situation prediction. The three-level situation estimation model is optimized to a more robust situation estimation ternary model. Combined with the database system, the reasoning learning mechanism and the diversified human-machine interface concept, a basic framework of intelligent situation awareness is completed. Secondly, the system’s flexible configuration method is demonstrated. Thirdly, some basic evaluation methods are given for the intelligent situation awareness’s performance metrics and multi-node consistency. Fourthly, the paper gives a typical electromagnetic situation estimation example for a drilling platform to explain and validate the theory. Finally, several suggestions are put forward for the next construction of intelligent situation awareness system.
A single-center prospective study on pain alleviation during peroral upper endoscopy with an ultrathin endoscope
Authors: Aya Iwao , Ichijima Ryoji , Sugita Tomomi , Nakayama Masako , Takasu Ayaka , Ogura Kanako , Gotoda Takuji , Kogure Hirofumi 
Published: March 2023

Abstract
Background
The efficacy of transnasal endoscopy using an ultrathin endoscope has been reported in several studies. However, few studies regarding peroral endoscopy with an ultrathin endoscopes with high resolution have been reported. This study investigates the pain alleviation of peroral endoscopy with an ultrathin endoscope.
Methods
Patients with a history of peroral endoscopy using a conventional, normal-diameter scope with no-sedation who underwent peroral esophagogastroduodenoscopy (EGD) using a thin scope between April-July 2022 were included in this study. After the procedure, the patients completed a questionnaire evaluating pain during the examination and willingness to repeat the procedure. The physicians were surveyed regarding their level of satisfaction. The primary endpoint was patient satisfaction, which corresponded to the rate of patients who rated the thin endoscope as more comfortable or somewhat more comfortable than the previously-used, conventional endoscope.
Results
One hundred forty-five patients were included in the analyses. Patient satisfaction was achieved in 86.2% (125/145) of patients. The median visual analog scale pain score was 3 (0–7) points in this study, which is significantly lower than the pain score after the previous endoscopy (5 (0–10) points; p < 0.001). In addition, 96% (24/25) of patients who underwent EGD by an expert and 95.8% (115/120) who underwent EGD by a non-expert were willing to repeat endoscopy using the thin scope (p = 0.69).
Conclusion
Peroral endoscopy using a thin scope reduces patient pain regardless of the endoscopist’s experience.
Achieving health-oriented air pollution control requires integrating unequal toxicities of industrial particles
Authors: Wu Di , Zheng Haotian , Li Qing , Wang Shuxiao , Zhao Bin , Jin Ling , Li Xiangdong , Hao Jiming 
Published: March 2023

Abstract
Protecting human health from fine particulate matter (PM) pollution is the ambitious goal of clean air actions, but current control strategies ignore the role of source-specific PM toxicity. Here, we proposed health-oriented control strategies by integrating the unequal toxic potencies of the most polluting industrial PMs. Iron and steel industry (ISI)-emitted PM2.5 exhibit about one order of magnitude higher toxic potency than those of cement and power industries. Compared with the current mass-based control strategy (prioritizing implementation of ultralow emission standards in the power sector), the proposed health-oriented control strategy (priority control of the ISI sector) could generate 5.4 times higher reduction in population-weighted toxic potency-adjusted PM2.5 exposure among polluting industries in China. Furthermore, the marginal abatement cost per unit of toxic potency-adjusted mass of ISI-emitted PM2.5 is only a quarter of that of the other two sectors under ULE scenarios. We highlight a health-oriented air pollution control strategy is urgently required to achieve cost-effective reductions in particulate exposure risks.
Experimental study on the influence of graded-loading rate on the creep-hardening effect of anthracite
Authors: Yue Shaofei , Wang Kai , Zhang Xiaoqiang , Kang Tianhe , Yan Jianbing , Jiang Yulong , Guo Zexiong 
Published: March 2023

Abstract
To investigate the influence of graded-loading rate on the creep characteristics and hardening effect of anthracite, creep tests at different graded-loading rates (0.01–0.1 mm/s) were performed on anthracite standard samples using the LDHJ-III triaxial creep-testing machine. The effect of graded-loading rate on the instantaneous strain increment, instantaneous elastic modulus, and decay characteristics of the strain rate in the creep stage were analyzed and discussed. The results revealed the following. With the increase in the graded-loading rate, especially when the loading rate was higher than 0.04 mm/s, the axial instantaneous strain increment was obvious, the radial-strain hysteresis was significant, the actual yield stress of the specimen was decreased, the “hardening” effect of the specimen was obvious, the strain rate attenuation in the creep stage was more rapid. The research results could quantitatively describe the “hardening” effect of the graded-loading rate on anthracite creep and predict the creep failure of an anthracite specimen.
WITHDRAWN: Systematic Review of the Efficacy of Gluten-Free/Casein-Free diet or Supplementary Diets to Alleviate Symptoms of Autism Spectrum Disorder in Children
Authors: Kazem Zeina 
Published: March 2023

Abstract
Purpose: The aim of this systematic review is to provide literature data about the efficacy and safety of specific biomedical dietary interventions on clinical aspects of children with autism.
Methods: Pubmed was used as the source of the medical database to conduct a literature search on this topic. The date of the publication was not a restriction. Consideration was given to prospective studies conducted in child and adolescent populations (age 0 to 18) and evaluating the changes in the behaviour of those with Autism Spectrum Disorder (ASD). The specific types of dietary interventions evaluated in this review are gluten/casein free diet, the use of probiotics/prebiotics, and briefly mentioning other emerging suggestions.
Results: Currently, while literature data is generally encouraging, additional randomized clinical trials are needed to provide more conclusive evidence about the effects of specific dietary interventions on the clinical aspects of autism.
Conclusion: This systematic review concludes that exclusion diets or dietary supplementation are effective adjuvant therapeutic agents; however, more detailed studies are recommended to develop more effective therapeutic methods to improve the quality of life of children with autism spectrum disorders.
Lethal suicidal intoxication with propafenone and diazepam: a case report
Authors: Yan Shuangbing , Chen Bingwei , Xin Ting , Luo Xiaojie , Wang Yu 
Published: March 2023

Abstract
Background: Diazepam poisoning is a common emergency situation in internal medicine, but propafenone poisoning is rare relatively. At present, there is no reported case of propafenone poisoning combined with diazepam.
Case presentation: An 18-year-old woman was admitted to our hospital with an overdose of oral propafenone and diazepam, who presented with convulsions and syncope. She was treated with cardiopulmonary resuscitation, rehydration, atropine, sodium bicarbonate, and vasopressors including dopamine，epinephrine, norepinephrine, isoproterenol, but sinus rhythm could not recovery and cardiac arrest occurred. Temporary pacemaker was implanted. However, even with multiple electrode positions, effective capture could not be achieved. The patient died eventually.
Conclusion: This was the first reported case of propafenone poisoning combined with diazepam. We should be alert to the possibility of propafenone poisoning when we find similar situations in arrhythmia patients.
Low preoperative serum total bilirubin level is a risk factor for intraoperative blood loss in the laparoscopic hepatectomy ---a retrospective study
Authors: Liu Yang , Li Nan , Yang Chun , Liu Cunming , Liu Shijiang 
Published: March 2023

Abstract
Background
Reduction of Intraoperative blood loss (IBL) is necessary for laparoscopic hepatectomy (LH). However, the risk factors before liver resection for IBL in LH is poorly understood. The research aimed to analyze the risk factors before liver resection for IBL in LH.
Methods
The data of consecutive patients who underwent LH for hepatocellular carcinoma from 2021 to 2022, were retrieved retrospectively. The patients were divided into two groups: the group A was for those with an IBL less than 250 mL (Group A, IBL༜250ml), and the group B was for those with an IBL more than 250 mL (Group B, IBL ≥ 250ml).
Results
We analyzed 246 patients who underwent LH. Median IBL was 250 (IQR: 100–500) ml in our research. Tumor size ≥ 3cm contributed to a higher level of IBL with Odds ratio of 2.496(95% CI 1.422–4.381, p = 0.001). High preoperative total bilirubin levels may be a protective factor for IBL ≥ 250ml and Odds ratio was 0.438༈95% CI 0.258–0.743, p = 0.002༉and a dose-response relationship was observed. In other words, low preoperative total bilirubin levels may be a risk factor for IBL ≥ 250ml. After correcting for other variables of characteristics, their statistical significance remained unchanged. The incidence of postoperative complications was 16.3%. The incidence of postoperative complications was significantly higher in Group B compared to Group A (21.8 vs. 10.7%, p = 0.018).
Conclusions
Increased IBL (≥ 250 ml) may adversely impact the short-term outcomes. In addition to tumor size, low preoperative serum total bilirubin level may be a risk factor for blood loss in LH.
A Flexible Pressure Sensor Based on an Interlocked Micropillars Array with Secondary Nanoprotrusions for Health Monitoring
Authors: Wen Li , Liao Lirui , Zhou Shuneng , Yang Junfeng , Wang Zekun , Li Jingjie , Qiu Ziqiang , Yu Zhongxin , Wang Hai 
Published: March 2023

Abstract
Flexible pressure sensors are an essential component in artificial systems to monitor human health. Recently, flexible pressure sensors with micro-nanostructures in interlocked geometry have attracted extensive attention because they effectively improve the sensing performance. However, it is a challenge that the fabrication methods are complex and expensive, and the layered interface between microstructure and nanostructure is unstable. Here, a flexible pressure sensor with an interlocked polydimethylsiloxane (PDMS) micropillar array combined secondary nanoprotrusions on their surfaces is proposed, which can be shaped in one step with merits of simplicity, controllability and low cost. The unique combined micro-nanostructures ensure the sensor with a wide linear range (0~32 kPa), relatively high sensitivity (26.08 Ω/kPa), low detection limit (15 Pa), fast response speed (response time is 56 ms, and relaxation time is 140 ms) and excellent stability (>1000 cycles). These superior properties set a foundation for applying the sensor in detecting various human physiological signals from pulse to joint deformation. Based on this sensor, a smart mask integrated system is proposed, displaying and recording breathing conditions in real time. These results demonstrate that the sensor can be used in health monitoring and disease diagnosis, as well as its potential application in other wearable devices.
Characterization of the extracellular vesicles, ultrastructural morphology, and intercellular interactions of multiple clinical isolates of the brain-eating amoeba, Naegleria fowleri
Authors: Russell A. Cassiopeia , Bush Peter , Grigorean Gabriela , Kyle Dennis E. 
Published: March 2023

Abstract
As global temperatures rise to unprecedented levels, so too do the latitudes of habitable niches for the pathogenic free-living amoeba, Naegleria fowleri. This opportunistic parasite causes a rare, but > 97% fatal, neurological infection called Primary Amoebic Meningoencephalitis. Despite its lethality, this parasite remains one of the most neglected and understudied parasitic protozoans. To better understand amoeboid intercellular communication, we elucidate the structure, proteome, and secretion mechanism of amoeba-derived extracellular vesicles (EVs), which are membrane-bound communication apparatuses that relay messages and can be used as biomarkers for diagnostics in various diseases. Herein we show that N. fowleri secretes EVs in clusters from the plasma membrane, from multivesicular bodies, and via beading of thin filaments extruding from the membrane. Fusion assays demonstrate that EVs are taken up by other amoebae and mammalian cells, and we observed a real-time increase in metabolic activity for mammalian cells exposed to EVs from amoebae. Proteomic analysis revealed > 2,000 proteins within the N. fowleri-secreted EVs, providing targets for the development of diagnostics or therapeutics. Our work expands the knowledge of intracellular interactions among these amoebae and subsequently deepens the understanding of the mechanistic basis of PAM.