bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D Climate Simulations of the Archean Find That Methane has a Strong Cooling Effect at High Concentrations
Authors: Eager‐Nash J. K. , Mayne N. J. , Nicholson A. E. , Prins J. E. , Young O. C. F. , Daines S. J. , Sergeev D. E. , Lambert F. H. , Manners J. , Boutle I. A. , Wolf E. T. , Kamp I. E. E. , Kohary K. , Lenton T. M. 
Published: March 2023

AbstractMethane is thought to have been an important greenhouse gas during the Archean, although its potential warming has been found to be limited at high concentrations due to its high shortwave absorption. We use the Met Office Unified Model, a general circulation model, to further explore the climatic effect of different Archean methane concentrations. Surface warming peaks at a pressure ratio pCH4:pCO2 of approximately 0.1, reaching a maximum of up to 7 K before significant cooling above this ratio. Equator‐to‐pole temperature differences also tend to increase up to pCH4 ≤ 300 Pa, which is driven by a difference in radiative forcing at the equator and poles by methane and a reduction in the latitudinal extend of the Hadley circulation. 3D models are important to fully capture the cooling effect of methane, due to these impacts of the circulation.
Shifts from cooperative to individual-based predation defense determine microbial predator-prey dynamics
Authors: de la Cruz Barron Magali , van Velzen Ellen , Klümper Uli , Weitere Markus , Berendonk Thomas U , Kneis David 
Published: March 2023

Abstract
Predation defense is an important feature of predator-prey interactions adding complexity to ecosystem dynamics. Prey organisms have developed various strategies to escape predation which differ in mode (elude vs. attack), reversibility (inducible vs. permanent), and scope (individual vs. cooperative defenses). While the mechanisms and controls of many singular defenses are well understood, important ecological and evolutionary facets impacting long-term predator-prey dynamics remain underexplored. This pertains especially to trade-offs and interactions between alternative defenses occurring in prey populations evolving under predation pressure. Here, we explored the dynamics of a microbial predator-prey system consisting of bacterivorous flagellates (Poteriospumella lacustris) feeding on Pseudomonas putida. Within five weeks of co-cultivation corresponding to about 35 predator generations, we observed a consistent succession of bacterial defenses in all replicates (n = 16). Initially, bacteria expressed a highly effective cooperative defense based on toxic metabolites, which brought predators close to extinction. This initial strategy, however, was consistently superseded by a second mechanism of predation defense emerging via de novo mutations. Combining experiments with mathematical modeling, we demonstrate how this succession of defenses is driven by the maximization of individual rather than population benefits, highlighting the role of rapid evolution in the breakdown of social cooperation.
Adaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation
Authors: González Lidice , Kolbin Daniel , Trahan Christian , Jeronimo Célia , Robert François , Oeffinger Marlene , Bloom Kerry , Michnick Stephen W. 
Published: March 2023

AbstractPartitioning of active gene loci to the nuclear envelope (NE) is a mechanism by which organisms increase the speed of adaptation and metabolic robustness to fluctuating resources in the environment. In the yeast Saccharomyces cerevisiae, adaptation to nutrient depletion or other stresses, manifests as relocalization of active gene loci from nucleoplasm to the NE, resulting in more efficient transport and translation of mRNA. The mechanism by which this partitioning occurs remains a mystery. Here, we demonstrate that the yeast inositol depletion-responsive gene locus INO1 partitions to the nuclear envelope, driven by local histone acetylation-induced polymer-polymer phase separation from the nucleoplasmic phase. This demixing is consistent with recent evidence for chromatin phase separation by acetylation-mediated dissolution of multivalent histone association and fits a physical model where increased bending stiffness of acetylated chromatin polymer causes its phase separation from de-acetylated chromatin. Increased chromatin spring stiffness could explain nucleation of transcriptional machinery at active gene loci.
Entangled spin-polarized excitons from singlet fission in a rigid dimer
Authors: Dill Ryan D. , Smyser Kori E. , Rugg Brandon K. , Damrauer Niels H. , Eaves Joel D. 
Published: March 2023

AbstractSinglet fission, a process that splits a singlet exciton into a biexciton, has promise in quantum information. We report time-resolved electron paramagnetic resonance measurements on a conformationally well-defined acene dimer molecule, TIPS-BP1', designed to exhibit strongly state-selective relaxation to specific magnetic spin sublevels. The resulting optically pumped spin polarization is a nearly pure initial state from the ensemble. The long-lived spin coherences modulate the signal intrinsically, allowing a measurement scheme that substantially removes noise and uncertainty in the magnetic resonance spectra. A nonadiabatic transition theory with a minimal number of spectroscopic parameters allows the quantitative assignment and interpretation of the spectra. In this work, we show that the rigid dimer TIPS-BP1' supports persistent spin coherences at temperatures far higher than those used in conventional superconducting quantum hardware.
Ligand vacancy channels in pillared inorganic-organic hybrids for electrocatalytic organic oxidation with enzyme-like activities
Authors: Chen Zhe , Li Jili , Meng Lingshen , Li Jianan , Hao Yaming , Jiang Tao , Yang Xuejing , Li Yefei , Liu Zhi-Pan , Gong Ming 
Published: March 2023

AbstractSimultaneously achieving abundant and well-defined active sites with high selectivity has been one of the ultimate goals for heterogeneous catalysis. Herein, we construct a class of Ni hydroxychloride-based inorganic-organic hybrid electrocatalysts with the inorganic Ni hydroxychloride chains pillared by the bidentate N-N ligands. The precise evacuation of N-N ligands under ultrahigh-vacuum forms ligand vacancies while partially retaining some ligands as structural pillars. The high density of ligand vacancies forms the active vacancy channel with abundant and highly-accessible undercoordinated Ni sites, exhibiting 5-25 fold and 20-400 fold activity enhancement compared to the hybrid pre-catalyst and standard β-Ni(OH)2for the electrochemical oxidation of 25 different organic substrates, respectively. The tunable N-N ligand can also tailor the sizes of the vacancy channels to significantly impact the substrate configuration leading to unprecedented substrate-dependent reactivities on hydroxide/oxide catalysts. This approach bridges heterogenous and homogeneous catalysis for creating efficient and functional catalysis with enzyme-like properties.
Evolutionary ecology of microbial populations inhabiting deep sea sediments associated with cold seeps
Authors: Dong Xiyang , Peng Yongyi , Wang Muhua , Woods Laura , Wu Wenxue , Wang Yong , Xiao Xi , Li Jiwei , Jia Kuntong , Greening Chris , Shao Zongze , Hubert Casey R. J. 
Published: March 2023

AbstractDeep sea cold seep sediments host abundant and diverse microbial populations that significantly influence biogeochemical cycles. While numerous studies have revealed their community structure and functional capabilities, little is known about genetic heterogeneity within species. Here, we examine intraspecies diversity patterns of 39 abundant species identified in sediment layers down to 430 cm below the sea floor across six cold seep sites. These populations are grouped as aerobic methane-oxidizing bacteria, anaerobic methanotrophic archaea and sulfate-reducing bacteria. Different evolutionary trajectories are observed at the genomic level among these physiologically and phylogenetically diverse populations, with generally low rates of homologous recombination and strong purifying selection. Functional genes related to methane (pmoAandmcrA) and sulfate (dsrA) metabolisms are under strong purifying selection in most species investigated. These genes differ in evolutionary trajectories across phylogenetic clades but are functionally conserved across sites. Intrapopulation diversification of genomes and theirmcrAanddsrAgenes is depth-dependent and subject to different selection pressure throughout the sediment column redox zones at different sites. These results highlight the interplay between ecological processes and the evolution of key bacteria and archaea in deep sea cold seep extreme environments, shedding light on microbial adaptation in the subseafloor biosphere.
Nanoscale imaging of super-high-frequency microelectromechanical resonators with femtometer sensitivity
Authors: Lee Daehun , Jahanbani Shahin , Kramer Jack , Lu Ruochen , Lai Keji 
Published: March 2023

AbstractImplementing microelectromechanical system (MEMS) resonators calls for detailed microscopic understanding of the devices, such as energy dissipation channels, spurious modes, and imperfections from microfabrication. Here, we report the nanoscale imaging of a freestanding super-high-frequency (3 – 30 GHz) lateral overtone bulk acoustic resonator with unprecedented spatial resolution and displacement sensitivity. Using transmission-mode microwave impedance microscopy, we have visualized mode profiles of individual overtones and analyzed higher-order transverse spurious modes and anchor loss. The integrated TMIM signals are in good agreement with the stored mechanical energy in the resonator. Quantitative analysis with finite-element modeling shows that the noise floor is equivalent to an in-plane displacement of 10 fm/√Hz at room temperatures, which can be further improved under cryogenic environments. Our work contributes to the design and characterization of MEMS resonators with better performance for telecommunication, sensing, and quantum information science applications.
Orbital design of Berry curvature: pinch points and giant dipoles induced by crystal fields
Authors: Mercaldo Maria Teresa , Noce Canio , Caviglia Andrea D. , Cuoco Mario , Ortix Carmine 
Published: March 2023

AbstractThe Berry curvature (BC)—a quantity encoding the geometric properties of the electronic wavefunctions in a solid—is at the heart of different Hall-like transport phenomena, including the anomalous Hall and the non-linear Hall and Nernst effects. In non-magnetic quantum materials with acentric crystalline arrangements, local concentrations of BC are generally linked to single-particle wavefunctions that are a quantum superposition of electron and hole excitations. BC-mediated effects are consequently observed in two-dimensional systems with pairs of massive Dirac cones and three-dimensional bulk crystals with quartets of Weyl cones. Here, we demonstrate that in materials equipped with orbital degrees of freedom local BC concentrations can arise even in the complete absence of hole excitations. In these solids, the crystals fields appearing in very low-symmetric structures trigger BCs characterized by hot-spots and singular pinch points. These characteristics naturally yield giant BC dipoles and large non-linear transport responses in time-reversal symmetric conditions.
Reversal of spin-polarization near the Fermi level of the Rashba semiconductor BiTeCl
Authors: Qu J. , Han X. , Sakamoto S. , Jia C. J. , Liu J. , Li H. , Guan D. , Zeng Y.-J. , Schüler M. , Kirchmann P. S. , Moritz B. , Hussain Z. , Devereaux T. P. , Shen Z.-X. , Sobota J. A. 
Published: March 2023

AbstractSpin–orbit coupling forms the physical basis for quantum materials with non-trivial topology and potential spintronics applications. The Rashba interaction is a textbook model of spin–orbit interactions, with charge carriers undergoing linear, isotropic spin-splitting in momentum space. Recently, non-centrosymmetric semiconductors in the family BiTeX (X = Cl, Br, I) have been identified as exemplary Rashba materials due to the strong splitting of their bulk bands, yet a detailed investigation of their spin textures, and their relationships to local crystal symmetry, is currently lacking. We perform high-efficiency spin-resolved photoemission spectroscopy to directly image the spin texture of surface states of BiTeCl, and we find dramatic deviations from idealized behavior, including a reversal of the spin-polarization near the Fermi level. We show that this behavior can be described by higher-order contributions to the canonical Rashba model with the surface states localized to individual trilayers of the crystal. Due to the prominence of these effects near the Fermi level, they should have a strong impact on the spin-dependent transport of carriers.
Mapping the terraces on the Loess Plateau based on a deep learning-based model at 1.89 m resolution
Authors: Lu Yahan , Li Xiubin , Xin Liangjie , Song Hengfei , Wang Xue 
Published: March 2023

AbstractTerraces on the Loess Plateau play essential roles in soil conservation, as well as agricultural productivity in this region. However, due to the unavailability of high-resolution (<10 m) maps of terrace distribution for this area, current research on these terraces is limited to specific regions. We developed a deep learning-based terrace extraction model (DLTEM) using texture features of the terraces, which have not previously been applied regionally. The model utilizes the UNet++ deep learning network as its framework, with high-resolution satellite images, a digital elevation model, and GlobeLand30 as the interpreted data and topography and vegetation correction data sources, respectively, and incorporates manual correction to produce a 1.89 m spatial resolution terrace distribution map for the Loess Plateau (TDMLP). The accuracy of the TDMLP was evaluated using 11,420 test samples and 815 field validation points, yielding classification results of 98.39% and 96.93%, respectively. The TDMLP provides an important basis for further research on the economic and ecological value of terraces, facilitating the sustainable development of the Loess Plateau.
A radioanatomical study of 3rd segment terminal branches of the maxillary artery in the pterygopalatine fossa
Authors: Lovász Kolos , Magyar Péter , Szalóki Tibor , Maurovich-Horvat Pal , Altdorfer Károly , Tamás László , Alpár Alán 
Published: March 2023

AbstractThis study describes the clinical anatomical topography and relationship of the terminal branches of the maxillary artery to the bony wall of the maxillary sinus in the pterygopalatine fossa (PPF) to estimate the bleeding risk during surgical interventions. Using contrasted computer tomography records, (i) the route of the maxillary artery in the infratemporal fossa, (ii) the number of the arteries in the critical PPF surgery plane, (iii) the diameter of the largest artery in the area and (iv) its relation to the posterior wall of the maxillary sinus were examined. Furthermore, measurements were extended with (v) the minerality of the bony posterior wall of the maxillary sinus on bone-window images. For statistical analyses Student’s t- and Fisher-test were applied. 50 patients (n = 50, 100 cases including both sides) were examined in this study. The maxillary artery reached the pterygomaxillary fissure on the lateral side of the lateral pterygoid muscle in 56% of the cases (n = 32), in 37% (n = 23) on its medial side and in 7% (n = 4) on both sides. The number of arteries at the level of the Vidian canal in the PPF varied between 1 and 4 with a median of 2. The diameter of the biggest branch was 1.2–4.7 mm, the median diameter was 1.90 mm. In 41% (n = 30) of the cases the biggest artery directly contacted the posterior wall of the maxillary sinus, and the mineral density of the posterior wall was decreased in 14.3% (n = 12) of all investigated cases. The present description and statistical analysis of the vasculature of the PPF optimizes operative planning—like clip size or the type and direction of the surgical approach—in this hidden and deep head/neck region.
A cortical biomarker of audibility and processing efficacy in children with single-sided deafness using a cochlear implant
Authors: Yaar-Soffer Y. , Kaplan-Neeman R. , Greenbom T. , Habiballah S. , Shapira Y. , Henkin Y. 
Published: March 2023

AbstractThe goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in children with single-sided deafness (CHwSSD) using a cochlear implant (CI). The P1 potential to acoustically-presented speech stimuli (/m/, /g/, /t/) was recorded during monaural [Normal hearing (NH), CI], and bilateral (BIL, NH + CI) listening conditions within a clinical setting in 22 CHwSSD (mean age at CI/testing 4.7, 5.7 years). Robust P1 potentials were elicited in all children in the NH and BIL conditions. In the CI condition: (1) P1 prevalence was reduced yet was elicited in all but one child to at least one stimulus; (2) P1 latency was prolonged and amplitude was reduced, consequently leading to absence of binaural processing manifestations; (3) Correlation between P1 latency and age at CI/testing was weak and not significant; (4) P1 prevalence for /m/ was reduced and associated with CI manufacturer and duration of CI use. Results indicate that recording CAEPs to speech stimuli in clinical settings is feasible and valuable for the management of CHwSSD. While CAEPs provided evidence for effective audibility, a substantial mismatch in timing and synchrony of early-stage cortical processing between the CI and NH ear remains a barrier for the development of binaural interaction components.
Differences in all-cause mortality risk associated with animal and plant dietary protein sources consumption
Authors: Haghighatdoost Fahimeh , Mohammadifard Noushin , Zakeri Parisa , Najafian Jamshid , Sadeghi Masoumeh , Roohafza Hamidreza , Sarrafzadegan Nizal 
Published: March 2023

AbstractThe relationship between protein intake and mortality is still controversial. We prospectively examined the associations of dietary protein sources with all-cause mortality risk in the Isfahan cohort study (ICS). A total of 5431 participants, aged ≥ 35 years, were enrolled in the ICS, in 2001 and followed through 2013. The frequency of protein intakes from different sources was estimated through a validated food frequency questionnaire at baseline. Any new case of death was recorded over the follow-up duration. Hazard ratio (HR)s and 95% confidence interval (CI)s were estimated through Cox proportional hazards regression models. During a median follow-up of 11.3 years, 483 deaths were documented. Higher intakes of plant proteins (HR = 0.64, 95% CI 0.46, 0.91) and animal proteins (HR = 1.52, 95% CI 1.13, 2.05) were associated with a decreased and increased risk of mortality, respectively. Additional adjustment for some mediators did not considerably affect the associations for animal protein (HR = 1.55, 95% CI 1.15, 2.09), whereas led to a tendency towards lower risk for plant protein in the top quintile compared with the bottom one (HR = 0.67, 95% CI 0.48, 0.95; P trend = 0.06). Among specific major sources, higher intakes of nuts and fish were associated with a 27% (95% CI 0.58, 0.93) and 21% (95% CI 0.62, 1.01) lower risk of mortality, respectively. The inverse association between plant protein and mortality risk might be mediated by some metabolic disorders. However, our results suggest an independent positive association for animal protein and all-cause mortality.
In vitro and in silico studies of 7′′,8′′-buddlenol D anti-inflammatory lignans from Carallia brachiata as p38 MAP kinase inhibitors
Authors: Nalinratana Nonthaneth , Suriya Utid , Laprasert Chanyanuch , Wisidsri Nakuntwalai , Poldorn Preeyaporn , Rungrotmongkol Thanyada , Limpanasitthikul Wacharee , Wu Ho-Cheng , Chang Hsun-Shuo , Chansriniyom Chaisak 
Published: March 2023

AbstractExcessive macrophage activation induces the release of high levels of inflammatory mediators which not only amplify chronic inflammation and degenerative diseases but also exacerbate fever and retard wound healing. To identify anti-inflammatory molecules, we examined Carallia brachiata—a medicinal terrestrial plant from Rhizophoraceae. Furofuran lignans [(−)-(7′′R,8′′S)-buddlenol D (1) and (−)-(7′′S,8′′S)-buddlenol D (2)] isolated from the stem and bark inhibited nitric oxide (half maximal inhibitory concentration (IC50): 9.25 ± 2.69 and 8.43 ± 1.20 micromolar for 1 and 2, respectively) and prostaglandin E2 (IC50: 6.15 ± 0.39 and 5.70 ± 0.97 micromolar for 1 and 2, respectively) productions in lipopolysaccharide-induced RAW264.7 cells. From western blotting, 1 and 2 suppressed LPS-induced inducible nitric oxide synthase and cyclooxygenase-2 expression in a dose-dependent manner (0.3–30 micromolar). Moreover, analysis of the mitogen-activated protein kinase (MAPK) signaling pathway showed decreased p38 phosphorylation levels in 1- and 2-treated cells, while phosphorylated ERK1/2 and JNK levels were unaffected. This discovery agreed with in silico studies which suggested 1 and 2 bound to the ATP-binding site in p38-alpha MAPK based on predicted binding affinity and intermolecular interaction docking. In summary, 7′′,8′′-buddlenol D epimers demonstrated anti-inflammatory activities via p38 MAPK inhibition and may be used as viable anti-inflammatory therapies.
A micromechanical study on the effects of precipitation on the mechanical properties of CoCrFeMnNi high entropy alloys with various annealing temperatures
Authors: Huang Chang-Wei , Su Pei-Ying , Yu Chi-Hua , Wang Chia-Ling , Lo Yu-Chieh , Jang Jason Shian-Ching , Hu Hsuan-Teh 
Published: March 2023

AbstractThe CoCrFeMnNi high entropy alloys remain an active field over a decade owing to its excellent mechanical properties. However, the application of CoCrFeMnNi is limited because of the relatively low tensile strength. Here we proposed a micromechanical model which adopted from the theory of dislocation density to investigate the strengthening mechanisms of precipitation of chromium-rich non-equiatomic CoCrFeMnNi alloy. The microstructures of CoCrFeMnNi were obtained directly from SEM-BSE images with different annealing temperatures. The proposed framework is validated by comparing simulations with experiments of uniaxial tensile tests on the CoCrFeMnNi alloys under different annealing temperatures. The stress–strain curves indicate that the precipitate has greater influence on post-yield hardening than the initial yielding strength. In addition, we identified that the particle distribution, controlled by the average size of the particle and the volume fraction of precipitation, can significantly enhance the strengthening effect. The numerical results indicate that HEAs with a precipitate distribution closer to a normal distribution and with smaller average size will tend to have higher strength and ductility.