bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTASI PENINGKATAN KUALITAS PERENCANAAN PEMBANGUNAN DAERAH OLEH BADAN PERENCANAAN PEMBANGUNAN, PENELITIAN DAN PENGEMBANGAN DAERAH DI KABUPATEN SUMEDANG
Authors: Amrin Amrin , Mahmud Mahmudah Kamal , Nurfurkon Ardika 
Published: August 2023

Perencanaan pembangunan merupakan proses dalam menetapkan suatu capaian yang terarah dengan adanya program dan sasaran, implementasi dan evaluasi. Masalah tersebut telah menunjukkan bagaimana Bappppeda sebagai perangkat daerah dalam implementasi peningkatan kualitas perencanaan pembangunan daerah. Kami menganalisis kualitas perencanaan berdasarkan indikator yang diimplementasikan pada Bappppeda Kabupaten Sumedang dan memberikan hasil yang akan berkontribusi pada pengembangan bidang perencanaan pembangunan. Dalam artikel ini, kami berpendapat bahwa kualitas perencanaan pembanguan yang baik dapat dilihat dengan penerapan prinsip-prinsip tata kelola perencanaan yang baik. Data yang digunakan dalam penelitian ini diperoleh dari studi literatur dan data sekunder (peraturan perundang-undangan, dokumen dan laporan perencanaan). Hasilnya menunjukkan bahwa adanya kualitas perencanaan pembangunan pada Bappppeda Kabupaten Sumedang dapat diunggulkan dengan adanya peningkatan pada keterlibatan unsur pemangku kepentingan dan peningkatan intensitas koordinasi perencanaan antar perangkat daerah yang terlibat dengan Bappppeda. Sedangkan hambatan yang ditemui yaitu proses pemantauan dan evaluasi terutama pada optimalisasi quality control data.

Kata Kunci: Perencanaan Pembangunan, Kualitas Perencanaan, Implementasi Pembangunan
Maternal health posts shared on Instagram: a content analysis of popular birthing and parenting accounts
Authors: George Nerissa , de Long Rachel , Ahmed Rukhsana , Kacica Marilyn , Manganello Jennifer A. 
Published: August 2023

IntroductionRecent studies have found that maternal health knowledge gaps exist among Black women, especially related to postpartum complications. The prenatal period is a key time when pregnant women have direct access to evidence-based sources, such as healthcare providers, to obtain maternal health and pregnancy information. Yet, Black pregnant women are also more likely to forgo or engage in prenatal care later than their White counterparts. In recent years, social media has become an essential source of pregnancy-related information and has been shown to effectively improve pregnancy knowledge. Social media has the potential to inform pregnant women about important pregnancy and postpartum health information. Yet, no studies to date have explored the type of maternal health content Black women are exposed to on popular pregnancy and parenting Instagram accounts.MethodsThis content analysis sought to identify what pregnancy topics appear and whether diverse birthing women's representation exists on Instagram accounts popular among birthing women. Instagram posts from three social media accounts commonly used for pregnancy and parenting information from 5/1/18 to 4/30/21 were collected and then screened for maternal health content.ResultsA total of 212 maternal health posts were identified. Maternal health content represented 5% (219 out of 4,572 posts) of all posts shared by all accounts. About 35% (69 out of 196) of the images shared on all of the accounts included people but lacked diversity.ConclusionThese results highlight significant missed opportunities to share maternal health and Black maternal health content to educate and promote diversity among women who utilize these popular parenting Instagram accounts. Social media can be a viable and innovative solution to help create and promote maternal health information equity.
Chemotherapy induced right ventricular cardiomyopathy; a systematic review and meta-analysis
Authors: Theetha Kariyanna Pramod , Kumar Ashish , Jayarangaiah Amog , Shetty Mrinali , Chowdhury Yuvraj , Das Sushruth , Jayarangaiah Apoorva 
Published: August 2023

BackgroundLeft ventricular dysfunction and cardiomyopathy are well documented adverse effects associated with chemotherapy agents. Limited information exists regarding the impact of chemotherapeutic agents on the integrity and function of the right ventricle (RV).ObjectivesThe current metanalysis compared pre- chemotherapy versus post- chemotherapy RV parameters measured on 2D echocardiography in patients receiving anthracycline and/or trastuzumab across all breast cancer patients.MethodsA systematic search across PubMed, EMBASE and Cochrane databases were performed from inception of the databases until November 2021 for relevant studies. We used the inverse variance method with a random effect model and DerSimonian and Laird method of Tau2 generation to calculate mean difference [MD] with 95% confidence interval [CI]. The analysis was carried out using RevMan Version 5.3 (Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014).ResultsFifteen studies, constituting total of 644 patients, met the inclusion criteria, with most studies having a follow up period of less than 12 months from initiation of chemotherapy. Anthracycline and/or Trastuzumab chemotherapy resulted in a statistically significant reduction in right ventricular ejection fraction (RVEF) at follow-up [MD: 2.70, 95% CI: 0.27 to 5.13, P-value- 0.03, I2- 71%, χ2P-value &lt; 0.05]. Treatment with Anthracycline and/or Trastuzumab chemotherapy resulted in a significant reduction in RV fractional area change (RVFAC) at follow-up [MD: 3.74, 95% CI: 1.33 to 6.15, P-value &lt; 0.01, I2- 68%, χ2P-value &lt; 0.05]. RV free wall longitudinal strain (RVFWLS) was lower at baseline, while LVEF was significantly reduced at follow-up [MD: -1.00, 95% CI: -1.86 to -0.15, P-value &lt; 0.05, I2- 0%, χ2P-value-0.40], [MD: 4.04, 95% CI: 2.08 to 6.01, P-value &lt; 0.01, I2- 91%, χ2P-value &lt; 0.05], respectively. However, treatment with Anthracycline and/or Trastuzumab chemotherapy had no statistically significant effect on Tricuspid annular plane systolic excursion (TAPSE) at follow-up [MD: 0.53, 95% CI: -0.11 to 1.17, P-value-0.11, I2- 98%, χ2P-value &lt; 0.05].ConclusionsChemotherapy with anthracyclines and trastuzumab negatively affects right ventricular function leading to decline in RVEF, RVFAC, RVFWLS and LVEF.
Population spatialization in Zhengzhou city based on multi-source data and random forest model
Authors: Liu Lingling , Cheng Gang , Yang Jie , Cheng Yushu 
Published: August 2023

Fine-scale population map plays an essential role in numerous fields, including resource allocation, urban planning, disaster prevention and response. Point of Interest (POI) data is widely used for population spatialization, but the types of POI are ignored. Since different types of POI data have different impacts on population distribution, this paper used typed POI data and other multi-source data to map population distributions at fine scales. At the township level, three random forest models were used to generate the population maps of 150 m, 300 m, and 500 m in 2020, enabling the downscaling of county-level population distribution to the grid level. The main influencing factors of population distribution were extracted and analyzed based on the feature importance output from the model. Zhengzhou city was used as a case for study. The experiments show the results of population spatialization for all three scales in this study have better fitting accuracy than that of the GPWv4 and LandScan datasets. The coefficient of determination (R2) is 0.8333 for 150 m gridded population, 0.8295 for 300 m, and 0.8224 for 500 m; POI types related to residence information have greater contributions to population spatialization than other features; typed POI data are more conducive to population spatialization.
Multiple teaching methods in undergraduate surgical training: a blended style may be the optimal choice!
Authors: Zhu Lingling , Zhang Qin , Zhang Yang 
Published: August 2023

BackgroundThere are various methods for teaching surgery to undergraduate students. Lecture-based learning (LBL) is a teacher-centered approach that comprehensively, accurately, and systematically conveys knowledge. Team-based, case-based, and problem-based learning methods are student-centered approaches that increase student enthusiasm and subject-related motivation. However, the COVID-19 pandemic disrupted conventional methods for teaching surgery to undergraduate students and its impact continues even today. This research investigates a variety of surgical teaching strategies and suggests optimal strategies for undergraduate students, especially within the context of the COVID-19 crisis.MethodsVarious teaching methods in undergraduate medical education that have emerged over the last 5 years are reviewed and analyzed, specifically those used for surgical training during the COVID-19 pandemic.ResultsTraditional in-person teaching methods have been replaced by novel approaches that increase efficiency, including social media adoption, simulation-based training, flipped-classroom concepts, and “Hand as Foot” teaching. However, traditional and novel approaches can be combined to teach students the fundamentals of science and basic surgical skills, which include incision, suturing and drainage, and chest tube insertion. Each method has its advantages and disadvantages under certain circumstances.ConclusionSeveral alternative teaching strategies and a combination of methods can complement traditional face-to-face learning, promoting the successful dissemination of academic knowledge and the improvement of clinical surgical skills in terms of objectivity, time-efficiency, and feasibility. The effects of the COVID-19 pandemic on the learning context can provide a reference for future teaching in response to unavoidable emergencies.
Univariable and multivariable Mendelian randomization investigating the effects of telomere length on the risk of adverse pregnancy outcomes
Authors: Han Xinyu , Wu Tianqiang , Liu Chun yan 
Published: August 2023

BackgroundNumerous observational studies have revealed a correlation between telomere length (TL) and adverse pregnancy outcomes (APOs). However, the impacts of TL on APOs are still unclear.MethodsMendelian randomization (MR) was carried out using summary data from genome-wide association studies (GWAS). Inverse variance weighted (IVW) was employed as the primary analysis to explore the causal relationship between TL and APOs. The exposure data came from a GWAS dataset of IEU analysis of the United Kingdom Biobank phenotypes consisting of 472,174 European participants. Summary-level data for five APOs were obtained from the GWAS datasets of the FinnGen consortium. We also performed multivariate MR (MVMR), adjusting for smoking, alcohol intake, body mass index (BMI), and number of live births. In addition, we conducted a series of rigorous analyses to further examine the validity of our MR findings.ResultsAfter Bonferroni correction and rigorous quality control, univariable MR (UVMR) demonstrated that a shorter TL was significantly associated with an increased risk of spontaneous abortion (SA) (odds ratio [OR]: 0.815; 95% confidence interval [CI]: 0.714–0.930; P = 0.002) and preterm birth (PTB) (OR: 0.758; 95% CI: 0.632-0.908; P = 0.003) in the IVW model. There was a nominally significant relationship between TL and preeclampsia (PE) in the IVW model (OR: 0.799; 95% CI: 0.651-0.979; P = 0.031). However, no significant association was found between TL and gestational diabetes mellitus (GDM) (OR: 0.950; 95% CI: 0.804-1.122; P = 0.543) or fetal growth restriction (FGR) (OR: 1.187; 95% CI: 0.901-1.565; P = 0.223) among the five statistical models. Furthermore, we did not find a significant causal effect of APOs on TL in the reverse MR analysis. MVMR analysis showed that the causal effects of TL on SA remained significant after accounting for smoking, alcohol intake, BMI, and number of live births.ConclusionOur MR study provides robust evidence that shorter telomeres were associated with an increased risk of SA. Further work is necessary to investigate the potential mechanisms. UVMR and MVMR findings showed limited evidence that TL affects the risk of PTB, PE, GDM, and FGR, illustrating that the outcomes of previous observational studies may have been confounded.
Vision difficulty and dementia: economic hardships among older adults and their caregivers
Authors: Kumar Priyanka , Chung Grace , Garcia-Morales Emmanuel , Reed Nicholas S. , Sheehan Orla C. , Ehrlich Joshua R. , Swenor Bonnielin K. , Varadaraj Varshini 
Published: August 2023

IntroductionLimited research has examined the economic impact of vision difficulty (VD) and dementia on older adults and their caregivers. We aimed to determine whether older adults with VD and/or dementia, and their caregivers, face more economic hardships than their counterparts without VD or dementia.MethodsWe used cross-sectional data from the 2015 National Health and Aging Trends Study (NHATS), a population-based survey of Medicare beneficiaries, linked to their family/unpaid caregivers from the National Study of Caregiving (NSOC). Regression models characterized the association of VD (self-report), dementia (survey and cognitive assessments), and co-occurring VD and dementia with debt, receiving financial help from relatives, government-based Supplemental Nutrition Assistance Program (SNAP), other food assistance, utility assistance, and caregiver financial difficulty.ResultsThe NHATS sample included 6,879 community-dwelling older adults (5670 no VD/dementia, 494 VD-alone, 512 dementia-alone, 203 co-occurring VD and dementia). Adults with VD and dementia had higher odds of receiving SNAP benefits (OR = 2.6, 95%CI = 1.4–4.8) and other food assistance (OR = 4.1, 95%CI = 1.8–9.1) than adults without VD/dementia, while no differences were noted for debt, financial help, and utility assistance. Adults with VD-alone had higher odds of debt (OR = 2.1, 95%CI = 1.3–3.2), receiving financial help (OR = 1.7, 95%CI = 1.1–2.5) and other food assistance (OR = 2.7, 95%CI = 1.7–4.3); while adults with dementia-alone had higher odds of debt (OR = 2.8, 95%CI = 1.4–5.5). The NSOC sample included 1,759 caregivers (995 caring for adults without VD/dementia, 223 for VD-alone, 368 for dementia-alone, and 173 for co-occurring VD and dementia). Compared to caregivers of older adults without VD/dementia, caregivers of adults with VD and dementia had higher odds of financial difficulty (OR = 3.0, 95%CI = 1.7–5.3) while caregivers of adults with VD-alone or dementia-alone did not.DiscussionWhile older adults with VD- or dementia-alone experienced increased economic hardships, disparities in food assistance were amplified among older adults with co-occurring disease. Caregivers of adults with co-occurring disease experienced more financial difficulty than caregivers of adults with a single or no disease. This study highlights the need for interventions across clinical and social services to support the economic wellbeing of our aging population and their caregivers.
Case report: Spontaneous lens absorption after the implantation of an implantable collamer lens
Authors: Liu Xiaojing , Zeng Qiulin , Lu Ting , Wang Min , Sun Yong , Zhang Jingfa 
Published: August 2023

BackgroundSpontaneous lens absorption is rare and usually occurs in eyes with certain syndromes, hyper-mature cataracts, and ocular trauma. The application of an implantable collamer lens (ICL) is widely performed in patients with high myopia for refractive correction. This study reports a case of spontaneous lens absorption after ICL implantation.Case summaryA 23-year-old man was referred with complaints of poor vision in his left eye. The patient had undergone binocular ICL implantation for refractive correction of high myopia 1.5 years prior. Approximately 10 months later, he experienced a sudden loss of vision and pain in his left eye, which resolved spontaneously the next day without any treatment. Since then, the visual acuity in his left eye gradually decreased. At presentation, slit-lamp examination revealed an ICL in the posterior chamber of both eyes, with anterior capsular fibrotic proliferation and posterior capsular opacity, and the residual lens cortex sandwiched between the anterior fibrotic membrane and opacified posterior lens capsule in his left eye. The number of corneal endothelial cells in his left eye was 1,337, which was lower than before ICL implantation (2,902). The patient then underwent ICL extraction, anterior capsular capsulotomy, residual cortex aspiration, posterior capsular polishing, and intraocular lens implantation.ConclusionsSpontaneous lens absorption may occur in patients with ICL implantation. Patients should undergo routine follow-ups after ICL implantation.
Swallowing sound evaluation using an electronic stethoscope and artificial intelligence analysis for patients with amyotrophic lateral sclerosis
Authors: Nakamori Masahiro , Ishikawa Ruoyi , Watanabe Tomoaki , Toko Megumi , Naito Hiroyuki , Takahashi Tamayo , Simizu Yoshitaka , Yamazaki Yu , Maruyama Hirofumi 
Published: August 2023

Background and purposeNon-invasive, simple, and repetitive swallowing evaluation is required to prevent aspiration pneumonia in neurological care. We investigated the usefulness of swallowing sound evaluation in patients with amyotrophic lateral sclerosis (ALS) using our new electronic stethoscope artificial intelligence (AI) analysis tool.MethodsWe studied patients with ALS who provided written informed consent. We used an electronic stethoscope, placed a Bluetooth-enabled electronic stethoscope on the upper end of the sternum, performed a 3-mL water swallow three times, and remotely identified the intermittent sound components of the water flow caused at that time by AI, with the maximum value as the swallowing sound index. We examined the correlation between the swallowing sound index and patient background, including swallowing-related parameters.ResultsWe evaluated 24 patients with ALS (age 64.0 ± 11.8 years, 13 women, median duration of illness 17.5 months). The median ALS Functional Rating Scale-Revised (ALSFRS-R) score was 41 (minimum 18, maximum 47). In all cases, the mean swallowing sound index was 0.209 ± 0.088. A multivariate analysis showed that a decrease in the swallowing sound index was significantly associated with a low ALSFRS-R score, an ALSFRS-R bulbar symptom score, % vital capacity, tongue pressure, a Mann Assessment of Swallowing Ability (MASA) score, and a MASA pharyngeal phase-related score.ConclusionSwallowing sound evaluation using an electronic stethoscope AI analysis showed a correlation with existing indicators in swallowing evaluation in ALS and suggested its usefulness as a new method. This is expected to be a useful examination method in home and remote medical care.
Combining brain-computer interfaces and multiplayer video games: an application based on c-VEPs
Authors: Moreno-Calderón Selene , Martínez-Cagigal Víctor , Santamaría-Vázquez Eduardo , Pérez-Velasco Sergio , Marcos-Martínez Diego , Hornero Roberto 
Published: August 2023

Introduction and objectiveVideo games are crucial to the entertainment industry, nonetheless they can be challenging to access for those with severe motor disabilities. Brain-computer interfaces (BCI) systems have the potential to help these individuals by allowing them to control video games using their brain signals. Furthermore, multiplayer BCI-based video games may provide valuable insights into how competitiveness or motivation affects the control of these interfaces. Despite the recent advancement in the development of code-modulated visual evoked potentials (c-VEPs) as control signals for high-performance BCIs, to the best of our knowledge, no studies have been conducted to develop a BCI-driven video game utilizing c-VEPs. However, c-VEPs could enhance user experience as an alternative method. Thus, the main goal of this work was to design, develop, and evaluate a version of the well-known ‘Connect 4' video game using a c-VEP-based BCI, allowing 2 users to compete by aligning 4 same-colored coins vertically, horizontally or diagonally.MethodsThe proposed application consists of a multiplayer video game controlled by a real-time BCI system processing 2 electroencephalograms (EEGs) sequentially. To detect user intention, columns in which the coin can be placed was encoded with shifted versions of a pseudorandom binary code, following a traditional circular shifting c-VEP paradigm. To analyze the usability of our application, the experimental protocol comprised an evaluation session by 22 healthy users. Firstly, each user had to perform individual tasks. Afterward, users were matched and the application was used in competitive mode. This was done to assess the accuracy and speed of selection. On the other hand, qualitative data on satisfaction and usability were collected through questionnaires.ResultsThe average accuracy achieved was 93.74% ± 1.71%, using 5.25 seconds per selection. The questionnaires showed that users felt a minimal workload. Likewise, high satisfaction values were obtained, highlighting that the application was intuitive and responds quickly and smoothly.ConclusionsThis c-VEP based multiplayer video game has reached suitable performance on 22 users, supported by high motivation and minimal workload. Consequently, compared to other versions of “Connect 4” that utilized different control signals, this version has exhibited superior performance.
The effects of rutin supplement on blood pressure markers, some serum antioxidant enzymes, and quality of life in patients with type 2 diabetes mellitus compared with placebo
Authors: Bazyar Hadi , Zare Javid Ahmad , Ahangarpour Akram , Zaman Ferdows , Hosseini Seyed Ahmad , Zohoori Vida , Aghamohammadi Vahideh , Yazdanfar Shima , Ghasemi Deh Cheshmeh Mohammad 
Published: August 2023

BackgroundThis trial aimed to investigate the effects of rutin supplement in type 2 diabetes mellitus (T2DM) patients.MethodsIn this trial with a double-blind and controlled design, fifty patients were randomly divided into intervention (n = 25) and control groups (n = 25) and were treated with 1 g of rutin or placebo for three months, respectively. At the baseline and end of the intervention, mean arterial pressure (MAP), heart rate (HR), pulse pressure (PP), systolic and diastolic blood pressure (SBP and DBP), serum levels of antioxidant enzymes, such as catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD) and quality of life (QOL) parameters, were evaluated.ResultsRutin consumption caused a significant reduction in SBP, DBP, PP, MAP, and HR, with a significant increase in SOD, CAT, and GPx and some QOL parameters (emotional limitations, energy and freshness, mental health, social performance, and general health) compared with baseline (p for all &lt;0.05). Also, the mean changes of emotional limitations, energy and freshness, mental health, and general health (unadjusted p for all &lt;0.05) and GPX and SOD (adjusted p for all &lt;0.05) were significantly higher in the rutin group compared with the placebo group. Although, in the supplement group compared with the placebo group, the mean changes of SBP, DBP, MAP, PP, and HR were significantly lower (adjusted p for all &lt;0.05).ConclusionRutin consumption improved blood pressure, the levels of antioxidant enzymes, and QOL in patients with T2DM.