bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gait Biomechanics While Walking Down an Incline After Exhaustion
Authors: Halder Amitava , Nordin Axel , Miller Michael , Gao Chuansi 
Published: April 2023

AbstractThis gait biomechanics study investigated stride length (SL), stride duration (SDN), the peak values of ground reaction forces (GRFspeak), required coefficient of friction (RCOFpeak), leg joints’ angles (anglepeak), angular velocity (angvelx.peak), angular acceleration (angaccx.peak), minimum angle (anglemin.) of the foot, and muscles’ electromyography (EMG) during the stance phase (SP) of the dominant leg following an exhaustive stair ascent on a stair machine. Data were collected by a three-dimensional motion capture system synchronized with EMG and force plate while walking down a 10° inclined stationary walkway. Although the leg muscles’ EMG showed no significant local muscle fatigue (LMF) during post-exhaustive walking downwards, the SL was significantly (p < 0.05) shorter than the pre-exhaustive. The mean vertical GRFzpeak. was significantly (p ≤ .01) reduced during late stance (LS) phase, however, the antero-posterior GRFypeak. was found to be significantly (p ≤ 0.01) higher. The RCOFpeak. was significantly (p ≤ .05) higher during the post-exhaustive walking downwards, LS phase. The available coefficient of friction value of ~ 0.350 seems to be the RCOF to reduce slips and falls on an inclined dry surface. None of the post-exhaustive lower limb joints’ anglepeak, anglemin., ang.velx.peak, and ang.accx.peak were significantly changed in post-exhaustion walking, except the knee ang.accx.peak., which was significantly (p < 0.05) increased during the LS period. The constrained post-exhaustive gait biomechanics indicate a perturbed gait, which may increase the risks for slips and fall-related accidents, when walking downwards and working on slopes. However, the non-significant joint angle changes imply that walking down is less demanding in a kinesiological perspective compared to walking up an incline.
Tracheal intubating conditions in elderly patients when train-of-four count is zero after rocuronium 0.6 or 0.9 mg/kg. A secondary analysis
Authors: Vested Matias , Hartoft Mian , Rasmussen Lars S 
Published: April 2023

AbstractPurpose: The neuromuscular blocking agent rocuronium can be administered to facilitate tracheal intubation. We hypothesized that rocuronium 0.9 mg/kg provided a larger proportion of patients with vocal cords in abducted position compared to rocuronium 0.6 mg/kg at train-of-four (TOF) 0. Methods: This secondary analysis was based on 52 elderly surgical patients of which 36 patients received rocuronium 0.6 mg/kg and 16 patients received rocuronium 0.9 mg/kg. Neuromuscular block was monitored with acceleromyography with TOF stimulation at the ulnar nerve. The primary outcome was the proportion of patients with vocal cords in abducted position at TOF 0. Secondary outcomes were intubating conditions evaluated by the Fuchs-Buder scale, the Intubating Difficulty Score (IDS), onset time, and duration of action of rocuronium. Results: At TOF 0, a significantly larger proportion of patients had vocal cords in abducted position in the rocuronium 0.9 mg/kg group (81%) compared with the rocuronium 0.6 mg/kg group (53%); difference (%) 28, 95% Cl 3–53, P = 0.05. Excellent intubating conditions (Fuchs-Buder) were more common in the rocuronium 0.9 mg/kg group (62.5%); difference (%) 32.5, 95% Cl 4–61), P = 0.03. No significant difference was found in IDS or onset time of rocuronium (difference 19 s, 95% Cl: -5–43). Duration of action was significantly longer (difference 29 min, 95% Cl: 10–47) in the 0.9 mg/kg group. Conclusion: The proportion of patients with vocal cords in abducted position was significantly larger after rocuronium 0.9 mg/kg compared to rocuronium 0.6 mg/kg at TOF 0 monitored at the ulnar nerve.
Animal Consumption Associated with Higher Intimate Partner Aggression
Authors: Taft Casey T. , Hamilton Evelyn G. , Leviyah Xenia , Gnall Katherine E. , Park Crystal L. 
Published: April 2023

Abstract
Purpose
This brief report examined associations between animal consumption and intimate partner aggression in a sample of undergraduates. Two possible explanatory variables for these associations, depressive symptoms and speciesism, were also examined.

Methods
Participants included 245 undergraduate students who provided electronic consent and completed a one-time anonymous survey.

Results
Results indicated that animal consumption was associated with higher use of physical and psychological intimate partner aggression, even after accounting for other correlates. Animal consumption was also associated with higher speciesism, and speciesism was associated with higher use of physical and psychological intimate partner aggression.

Conclusions
Results extend findings from prior studies documenting links between animal consumption and negative outcomes and further suggest that speciesism may play a role in understanding links between animal consumption and intimate partner aggression.
Rhodamine 6G Dye Adsorption Using Magnetic Nanoparticles Synthesized With the Support of Vernonia Amygdalina Leaf Extract (Bitter Leaf)
Authors: Aigbe Uyiosa Osagie , Maluleke Rodney , Lebepe Thabang Calvin , Oluwafemi Oluwatobi Samuel , Osibote Otolorin Adelaja 
Published: April 2023

AbstractThis study reports the synthesis of magnetic nanoparticles (MNPs) using the co-precipitation method with the support of Vernonia Amygdalina (VA) (bitter leaf) extract for the efficient sequestration of rhodamine 6G dye (Rhd 6G) from a water-soluble solution. The prepared MNPs were characterized using Transmission electron microscopy (TEM,) X-ray Diffraction (XRD), Fourier-transform infrared (FTIR) and Ultraviolet–visible (UV–Vis) spectrometry. The average particle sizes from TEM and XRD analyses were 4.81 ± 2.2 nm and 5.61 nm respectively. The sorption of Rhd 6G dye to the MNPs was pH-dependent, with ideal confiscation of dye molecules observed at pH 10 ($$\sim 91.4\%)$$

∼
91.4
%
)

. The sorption process of Rhd 6G dye was reported to follow the Freundlich (FRH) isotherm model, while the pseudo-first-order model (PFOM) best depicted the sorption process of Rhd 6G dye to the MNPs from the non-linear modelling. The determined sorption capacity of the MNPs was established to be 454 mg.g−1. Also, the sorption of Rhd 6G dye to the MNPs was observed to be thermodynamically spontaneous, endothermic and with increasing randomness between the interface of the water-soluble solution and the MNPs. Hence, the prepared MNPs have proven to be an effective potential magnetic sorbent for the removal of cationic dyes from an aqueous solution.
Graphical Abstract
Synthesis, Physicochemical Characterization, Biological Assessment, and Molecular Docking Study of Some Metal Complexes of Alloxan and Ninhydrin as Alterdentate Ligands
Authors: Masoud Mamdouh S. , Yacout Galila A. , Abd-El-Khalek Bassant A. , Ramadan Ahmed M. 
Published: April 2023

AbstractA series of transition metal complexes of alloxan monohydrate (H2L1) and ninhydrin (H2L2) have been prepared where metal ions are Fe(III), Co(II), Ni(II), Cu(II), Zr(IV), and Mo(VI). Different microanalytical techniques, spectroscopic methods, and magnetic studies were applied to assign the mode of bonding and elucidate the structure of complexes. All solid complexes are of 1:1 (M:L) stoichiometry and octahedral geometry except nickel (II) complexes exist in a tetrahedral geometry. FTIR spectral interpretation reveals that HL1 coordinates to the central metal ion in a bidentate ON pattern, whereas HL2 behaves as an alterdentate ligand through hydroxyl oxygen and carbonyl oxygen either C(1) = O or C(3) = O. The thermal behavior of some complexes was followed up to 700 °C by different techniques (TGA, DTA, and DSC) where decomposition stages progress in complicated mechanisms and are ended by the formation of metal oxide residue. Besides, biological screening involving antioxidant, antibacterial, and antifungal for ligands and some of their complexes was done. Moreover, four examined metal complexes displayed anticancer activity against hepatocellular carcinoma cells (HepG-2) but to different degrees. According to the IC50 values, Cu-ninhydrin complex, [Cu(HL2)(H2O)4].Cl has a better potency impact in comparison with cisplatin which was used as a reference control. This is in harmony with the molecular docking simulation outcomes that predicted a good binding propensity of the Cu-ninhydrin complex with hepatocellular carcinoma protein (2jrs). Therefore, the Cu-ninhydrin complex should be deemed as a potential chemotherapeutic agent for hepatocellular cancer.
Graphical Abstract
Canopy gap patterns in Mediterranean forests: a spatio-temporal characterization using airborne LiDAR data
Authors: Rodes-Blanco Marina , Ruiz-Benito Paloma , Silva Carlos A. , García Mariano 
Published: April 2023

Abstract
Context
In the last century European forests are experiencing tree damage and mortality rise and it is expected to continue due to increased disturbances under global change. Disturbances generally creates canopy gaps, which leads to secondary succession, compositional changes and landscape mosaic transformations. Forest gap characterization has traditionally been performed in light-limited tropical and boreal forests, but no studies have been found on water-limited Mediterranean forests. Characterising canopy gaps and their dynamics in Mediterranean forests will help to better understand their dynamics across landscapes under ongoing global change.

Objectives
We aimed to characterize canopy gaps and quantify their dynamics identifying hotspots of openings and closings in Mediterranean forests.

Methods
We used low density multitemporal airborne LiDAR data between 2010 and 2016, over a large region (Madrid, Spain, 1732.7 km2) with forests ranging from monospecific conifer and broadleaved to mixed forests, to delineate canopy gaps. The characterization was made through its Gap Size Frequency Distribution (GSFD) by forest type and year. We analysed canopy gap dynamics and identified statistically significant hotspots of gap openings and closings in each forest type.

Results
There were major differences between conifers and broadleaved forest in terms of gap characteristics and GSFD. In general, we found a great dynamism in Mediterranean forests with high rates of forest openings and closings, but a net closing trend. A high spatial heterogeneity was observed finding hotspots of gap openings and closings across the entire study area.

Conclusions
We characterised for the first-time large-scale structure and dynamics of canopy gaps in Mediterranean forests. Our results represents the characterisation of the GSFD of Mediterranean forests and could be considered a benchmark for future studies. The provision of up-to-date periodic maps of hotspots of gap opening, closing and net change help to understand landscape mosaic changes as well as to prioritise forest management and restoration strategies.
Approaching Legal Multinomials from the Sociolinguistic Perspective – Insights into Authorship-Based Distinctions
Authors: Więcławska Edyta 
Published: April 2023

AbstractThe paper explores the hypothesis that multinomials can act as authorship-based style distinguishing markers in legal communication. Specifically, the analysis focuses on identifying the quantitative distribution patterns of structural categories of multinomials as typical for two authorship categories and on their communicative function. The two authorship categories that are contrasted here are legal professionals/experts and lay people. The analysis is conducted in the corpus-based methodology with a custom-designed corpus of English, authentic texts found in the legal trade, in the domain of company registration proceedings. The findings confirm that multinomials that are conventionally considered to be a feature of professional legal communication are also cognitively salient in lay communication. Further, the texts drafted by the two categories of authors are profiled by structurally distinct multinomials. Functionally, it has been demonstrated that the structurally distinct types of multinomials that are found quantitatively salient in the two authorship categories are used predominantly for specific stylistic and/or pragmatic functions. Stylistically, multinomials contribute to conventional and ritual patterns which are used to meet the formality standards that have evolved in specific legal professions where authority is of particular importance. Pragmatic factors which account for quantitative salience of specific, structurally profiled categories of multinomials involve mainly reduplication of multinomials that embody norm-related concepts, which is required on the ground of intertextuality and ensures the materialisation of legal effect.
Quantification of sarcopenia in patients with rheumatoid arthritis by measuring the cross-sectional area of the thigh muscles with magnetic resonance imaging
Authors: Salaffi Fausto , Carotti Marina , Poliseno Anna Claudia , Ceccarelli Luca , Farah Sonia , Di Carlo Marco , Giovagnoni Andrea 
Published: April 2023

Abstract
Purpose
To determine the utility of cross-sectional area (CSA) measurements on magnetic resonance imaging (MRI), at the level of the thigh muscles, to estimate muscle mass in discriminating rheumatoid arthritis (RA) patients with sarcopenia from those without.

Materials and methods
Consecutive female RA patients were enrolled for this cross-sectional study. Patients were assessed for disease activity, radiological damage, handgrip strength, physical performance and for the presence of sarcopenia, identified in accordance with the EWGSOP2 criteria. A 1.5 T MRI machine was used to scan the thigh muscles. A dimensional region growth algorithm (Horos™) was used to segment the muscles CSAs (in cm2) on MR images located 25 cm above the knee joint (MRI-CSA-25). The MRI-CSA-25 was obtained by summing the CSAs of the individual muscles. MRI-CSA-25 was correlated (Pearson's r) with the other variables, and its optimal cut-off point (Youden index) for sarcopenia diagnosis was identified in relation to the EWGSOP2 criteria.

Results
32 RA female patients were studied, 34.4% diagnosed as sarcopenic. The mean MRI-CSA-25 was 151.00 cm2 for patient with sarcopenia, 275.57 cm2 for patient without sarcopenia (p < 0.001). MRI-CSA-25 correlated significantly with measures of physical performance, and disease activity, but not with radiological damage or age. The MRI-CSA-25 optimal cut-off point in discriminating sarcopenic patients was identified at 182.00 cm2 (AUC-ROC = 0.894).

Conclusion
MRI-CSA-25 can differentiate sarcopenic versus non-sarcopenic RA patients, representing an imaging biomarker of this condition.
Clinical evaluation of patients living with obesity
Authors: Dobbie Laurence J. , Coelho Claudia , Crane James , McGowan Barbara 
Published: April 2023

AbstractObesity is a significant public health concern which is implicated in cardiometabolic disease, mechanical complications and psychiatric sequelae. BMI is currently used for diagnosis; however, it has limited sensitivity for adiposity in certain circumstances. This has led to the development of risk stratification tools like the Edmonton Staging criteria and the Kings Obesity Staging Criteria: these facilitate and guide comprehensive obesity-related complication assessment. Healthcare professionals working within obesity clinics should adopt evidence-based communication strategies, including shared decision-making, motivational interviewing, and realistic goal setting. It is also vital to avoid weight-stigmatising terminology in all aspects of care, as this can negatively impact patients. Primary care plays an essential part in obesity care and should work to promptly identify cases, initiate treatment and forward on to specialist services where appropriate. Clinical evaluation of the patient living with obesity should take a holistic approach and involve input from bariatric physicians, dietitians, psychologists, and bariatric surgeons, wider members of the multi-disciplinary team should be involved where needed. Clinicians should take a detailed history, examination and order laboratory tests to investigate for complications. Overall, with appropriate evaluation, these assessments can guide patient management and facilitate long-term improvement in health.
Cost awareness amongst irish ophthalmologists
Authors: Power Barry 
Published: April 2023

Abstract
Background
Healthcare systems have increasingly limited and stretched budgets. Clinicians have a key role in budget allocation. Awareness of the costs of high-use clinical items is important.

Aims
Assess awareness of the cost of commonly utilised clinical items amongst Irish Ophthalmologists

Methods
Irish ophthalmologists were contacted and asked to fill out an anonymous survey. We assessed knowledge of hospital costs of surgical materials, medications and anti VEGF drugs as well as retail pharmacy costs of commonly prescribed medications. The cost of items to the hospital was recorded from pharmacy and ward order receipts from a single university hospital. The costs of items to the patient were calculated by taking an average of 3 prices charged by local retail pharmacies. For each estimate we calculated the absolute error from the true price. We calculated the mean absolute errors (MAE) and percentage errors (MAPE) across the different groups.

Results
We received responses from 47 participants (15 Senior House Officers, 11 Registrars, 21 Consultant/Community Ophthalmologists). Despite 70% of respondents agreeing that the cost of an item should have a major role in its use, the average estimate was 124% inaccurate. Less than 50% of responses were within 50% of the true cost of the item. Self-perceived knowledge was acknowledged to be limited or very limited in 73% of responses.

Conclusions
We demonstrate variable and limited levels of cost awareness. Seniority and better self-perceived knowledge were not found to be associated with better estimate accuracy.
Circular RNAs: Promising Targets in Osteoporosis
Authors: Moura Sara Reis , Fernandes Maria João , Santos Susana G. , Almeida Maria Inês 
Published: April 2023

Abstract
Purpose of Review
Circular RNAs (circRNAs) are RNA transcripts derived from fragments of pre-messenger RNAs through a back-splicing process. An advantage that rises from their circular covalently closed conformation is their high stability, when compared with their linear counterparts. The current review focuses on the emerging roles of circRNAs in osteoporosis, including in osteogenic differentiation and osteoclastogenesis. Their potential as osteoporosis biomarkers will also be discussed.

Recent Findings
Although firstly described as non-coding, some of these single-stranded RNAs were recently reported to possess protein-coding capacity. On the other hand, the circRNAs exhibit cell and tissue-specific patterns at the transcriptome level in eukaryotes and are regulated throughout the development or disease progression. Even though thousands of these circular transcripts are listed and annotated, only a limited number of studies describe their biological role in bone processes. Recent evidence indicates inhibitory activator roles in both osteoblasts and osteoclasts differentiation and function. Latest screenings in the blood, plasma, or serum of osteoporosis patients support the potential for circRNA signature to be used as biomarkers in osteoporosis, but further validation is required.

Summary
While intense research into circRNAs has been detailing their biological roles, there remains a need for standardization and further research to fulfil the future potential of this emerging and highly promising class of regulatory molecules.
Graphical Discrimination of New Zealand Honey from International Honey Using Elemental Analysis
Authors: Grainger Megan N. C. , Klaus Hannah , Hewitt Nyssa , Gan Han , French Amanda D. 
Published: April 2023

AbstractThis study investigated the potential of utilising the elemental fingerprinting of honey to differentiate New Zealand (NZ) honey from that of international origin. Twenty elements were analysed by ICP-MS in 352 honeys from 34 various countries. Of these, 323 honeys (245 New Zealand honeys, 78 international) and two subsets of data (NZ and European origin, n = 306, and, NZ and Denmark/Germany, n = 280) were visualised using principal component analysis (PCA). For the NZ/Europe subset, 42.2% of data was explained in the first two principal components. Statistical classification rules were also derived using linear discriminant analysis (LDA) and decision tree analysis. Various combinations of elements were explored for classification, considering the effect of soil-derived elements and those from anthropogenic sources. A high degree of accuracy (at least 90%) for the characterisation of New Zealand honey was observed for all statistical models, showing the robustness of these analyses. When using decision tree analysis to distinguish New Zealand samples from international samples, a tree with five terminal nodes (using Cs, Ba and Rb) was created with 92.4% accuracy. This work has demonstrated that elemental fingerprints of honey are a promising tool for categorising New Zealand honey from other geographical locations.
The Hirschfeld Equation and the Queer Afro-Modern
Authors: Gevisser Mark 
Published: April 2023

AbstractIn 1904, seven years after he founded the world’s first homosexual rights movement, the German sexologist Dr. Magnus Hirschfeld published a slim volume calledBerlin’s Third Sex, which detailed the city’s extensive queer life. If Hirschfeld was a pioneer in establishing the founding truth of what we now call the “LGBTQ Rights Movement”—that visibility brings equality—he understood something quite contradictory about the power of the city in this process: it allows you to hide in plain sight. He formulated an equation for queer urban life that has proven to be startlingly durable: “That which is hidden from the uninitiated in the metropolis can be all the more easily discovered by the initiate because it is far less constrained.” In the last few decades, African cities have boomed. The forces of globalization—the digital revolution, industrialization, and rapid urbanization—mean that queer communities have seeded in these cities in ways that are quite similar to the dynamics in Berlin in the twentieth century. But the differences, over time and space, and given the politics of the twenty-first century, are very marked too. This essay thinks with Hirschfeld about the dynamics of visibility and urbanism in African cities today, using research I conducted in Egypt, Uganda, Nigeria, and Senegal for my 2020 book,The Pink Line: Journeys across the world’s queer frontiers,as well as other contemporary African texts.