bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computerised tomography brain findings in male patients with alcohol dependence syndrome: A hospital based cross sectional study
Authors: Suchak Vatsal , Kakunje Anil , Reddy Vishwanath 
Published: August 2023

ABSTRACT

Background:
Alcohol dependence syndrome (ADS) is a set of mental, emotional and physiological effects of drinking alcohol daily. This study aimed to assess the computerised tomography (CT) brain findings in patients with ADS and to compare it with age-matched controls.

Aims:
To study the relationship of CT-Brain findings in Male patients with alcohol dependence syndrome and compare it with controls.

Materials and Methods:
This retrospective study was carried out after obtaining clearance from the institution’s ethics committee between 1 January 2021 and April 2022. Medical records of 64 patients were examined, of which 32 patients with the diagnosis of ADS who had already undergone CT brain Neuroimaging and 32 age- and sex-matched normal controls, were randomly selected and parameters were compared to look at cortical atrophy, cella media index (CMI), the maximum width of the third, fourth ventricle, frontal subarachnoid space, Evans ratio, the maximum width of the anterior interhemispheric fissure and maximum width of the Sylvian fissure (MSF).

Results:
The study detected that the mean age of cases was 41.96 years, and in controls, it was 40.91 years with no significant difference. There was a significant difference in the mean level of CMI, the maximum width of the third and fourth ventricle, frontal subarachnoid space, the maximum width of the anterior hemispheric fissure and the MSF amongst the cases compared to controls.

Conclusion:
Compared to controls, there was a significant change in CT brain findings amongst the ADS patients.
An intriguing case of episodic hypersomnolence- Kleine–Levin syndrome, a diagnosis often missed
Authors: Chauhan Shreya , Sabharwal Ramakant K. , Kumar Praveen , Paul Paramita 
Published: August 2023

ABSTRACT
A sleep disorder is characterised by alteration in normal pattern of sleep enough to interfere with the normal functioning of an individual. Sleep disorders are broadly classified as primary sleep disorders such as dyssomnias, hypersomnia and parasomnias and secondary due to medical and mental disorders such as anxiety or substance abuse. We report the case of a 12-year-old boy who presented to us with episodic hypersomnolence, hyperphagia and behavioural abnormalities and was initially managed as epilepsy at another hospital. He was subsequently diagnosed as primary sleep disorder, Kleine–Levin syndrome. We also describe the diagnostic approach to such a case and the crucial role of functional brain imaging in it.
The pattern of antimicrobial resistance and the presence of the vaginolysin gene in Gardnerella vaginalis isolates from pregnant women
Authors: Tripathi Deepika , Saxena Rishi Kumar , Agarwal Sippy 
Published: August 2023

ABSTRACT

Background:
Bacterial vaginosis (BV) is a common vaginal infection, with Gardnerella vaginalis being the predominant microorganism responsible. BV causes vaginal discharge and irritation and is associated with adverse pregnancy outcomes. Vaginalis produces a pore-forming protein toxin, vaginolysin (VLY), which is essential for virulence and plays a role in the pathogenesis of BV.

Aim:
This study aimed to investigate the prevalence of the VLY gene in isolates of G. vaginalis from pregnant women and to determine their antibiotic sensitivity patterns.

Materials and Methods:
Vaginal secretions were collected from 250 pregnant women and processed for G. vaginalis isolation. Presumptive identification of the isolates was done by Amsel’s criteria, b▯haemolysis and oxidase and catalase tests. A polymerase chain reaction was used to confirm the bacterial identity and detect the VLY gene. Anti▯microbial susceptibility patterns were determined for metronidazole, nitrofurantoin, sulphonamides, chloramphenicol and ampicillin.

Results:
Out of 250 swabs examined, 72 (28.8%) were positive for G. vaginalis, with 59 from BV patients and 13 from non▯BV patients. The VLY gene was detected in 33.3% of G. vaginalis isolates from non▯BV patients and in 66.6% of those from BV symptomatic patients. Metronidazole and chloramphenicol showed a high sensitivity of 66.6%.

Conclusion:
The study concludes that regional drug susceptibility studies should be conducted to reduce the phenomenon of bacterial resistance. Further prospective research is needed to understand the function of G. vaginalis in the pathogenesis of BV.
Prevention and treatment of noncognitive complications
Authors: van Zundert André , Gatt Stephen P. , van Zundert Tom Christophe 
Published: August 2023

ABSTRACT
Patients aged 65 and older are the fastest growing segment in the population of many countries. Based on evolving demographics showing increasing life expectancies, it is expected that there will be a concurrent rise in the demand for a large variety of surgical and anesthesia services. Surgery offers definitive management of many age-related diseases and provides symptom-relieving (morbidity) and life-extending (mortality) benefits. However, elderly adult surgical patients, especially the frail ones, often require a different level of care than younger patients during the perioperative period. As many have chronic illnesses and acquired deconditioning and functional decline, older patients are prone to develop untoward outcomes such as postoperative complications and loss of independence. This manuscript focuses on the holistic quality person-centered care, supported by a wide stakeholder team of health-care workers, ensuring fidelity to comprehensive geriatric assessment and optimization services where possible, offering a systematic approach to early health risk assessment and risk modification in the perioperative period, with the ultimate goal of reducing postoperative complications and health-care costs. The “comprehensive geriatric assessment and optimization” cost-effective approach builds on robust evidence with older people more likely to be alive, a shorter length of hospital stay due to fewer postoperative medical complications, and improved rates of return to usual residence. Prehabilitation programs are delivered focusing on primary (through counseling) and secondary prevention (through screening) with an aim to improve fitness for surgery, by evaluating functional capacity, nutritional and psychological health, prompting interventions, targeting physical exercise, lifestyle and nutritional advice, and psychological support.
A systematic review of predictive accuracy via c-statistic of preoperative frailty tests for extended length of stay, post-operative complications, and mortality
Authors: Dunlop Richard A. N. , Van Zundert André 
Published: August 2023

ABSTRACT
Frailty, as an age-related syndrome of reduced physiological reserve, contributes significantly to post-operative outcomes. With the aging population, frailty poses a significant threat to patients and health systems. Since 2012, preoperative frailty assessment has been recommended, yet its implementation has been inhibited by the vast number of frailty tests and lack of consensus. Since the anesthesiologist is the best placed for perioperative care, an anesthesia-tailored preoperative frailty test must be simple, quick, universally applicable to all surgeries, accurate, and ideally available in an app or online form. This systematic review attempted to rank frailty tests by predictive accuracy using the c-statistic in the outcomes of extended length of stay, 3-month post-operative complications, and 3-month mortality, as well as feasibility outcomes including time to completion, equipment and training requirements, cost, and database compatibility. Presenting findings of all frailty tests as a future reference for anesthesiologists, Clinical Frailty Scale was found to have the best combination of accuracy and feasibility for mortality with speed of completion and phone app availability; Edmonton Frailty Scale had the best accuracy for post-operative complications with opportunity for self-reporting. Finally, extended length of stay had too little data for recommendation of a frailty test. This review also demonstrated the need for changing research emphasis from odds ratios to metrics that measure the accuracy of a test itself, such as the c-statistic.
Regional anesthesia for geriatric population
Authors: Al Harbi Mohammed K. , Alshaghroud Salah M. , Aljahdali Mohammed M. , Ghorab Fadi A. , Baba Fayaz , Al Dosary Rayan , Bahadeq Mohammed 
Published: August 2023

ABSTRACT
Advancements in modern health care over 20 years have substantially increased the average lifespan in developed countries, and the fastest growing population is the elderly population. The proportion of people in Saudi Arabia aged 60 or more is predicted to be 25 percent of the total population of 40 million by the end of 2050. Moreover, the number of people aged 80 or more is expected to reach 1.6 million or 4 percent of the total population in the same period. Improvements in surgical techniques, anesthesia, and intensive care units make surgical interventions in older and sicker patients possible. It is estimated that over half of the population older than 65 years will require surgical intervention at least once during the remainder of their lives. Therefore, elderly patients are becoming an even larger part of anesthetic practice. Regional anesthesia (RA) is frequently used in elderly patients, especially during orthopedic surgery, genitourologic and gynecologic procedures, and hernia repair. Although age can no longer be considered a contraindication to anesthesia and surgery, anesthesia-related morbidity and mortality remain higher among elderly than among young adult surgical patients. Undoubtedly, peripheral nerve (PN) blocks improve analgesia and reduce opioid consumption and their associated side effects. This is beneficial in the perioperative care of elderly patients who may have less physiologic reserve to withstand the side effects of general anesthesia (GA).
Postoperative cognitive recovery and prevention of postoperative cognitive complications in the elderly patient
Authors: Almuzayyen Hisham A. , Chowdhury Tumul , Alghamdi Abdulkareem S. 
Published: August 2023

ABSTRACT
Elderly patients undergoing surgery are at higher risk of life-altering and costly complications. This challenge is increasingly recognized with the growing geriatric surgical population. Advanced age and comorbid conditions, such as disability and frailty that often develop with age, are all independent risk factors of postoperative morbidity and mortality. A common factor in this age group is cognitive impairment, which poses a challenge for the patient and clinician in the perioperative setting. It affects the capacity for informed consent and limits optimization before surgery; furthermore, an existing impairment may progress in severity during the perioperative period, and new onset of signs of delirium or postoperative cognitive dysfunction may arise during postoperative recovery. In this article, we aim to review the current literature examining the latest definitions, diagnostic criteria, and preventive strategies that may ameliorate postoperative cognitive complications.
Preoperative evaluation of the elderly patient
Authors: Schipa Chiara , Luca Ersilia , Ripa Matteo , Sollazzi Liliana , Aceto Paola 
Published: August 2023

ABSTRACT
Nowadays, the pre-operative evaluation of older patients is a critical step in the decision-making process. Clinical assessment and care planning should be considered a whole process rather than separate issues. Clinicians should use validated tools for pre-operative risk assessment of older patients to minimize surgery-related morbidity and mortality and enhance care quality. Traditional pre-operative consultation often fails to capture the pathophysiological and functional profiles of older patients. The elderly’s pre-operative evaluation should be focused on determining the patient’s functional reserve and reducing any possible peri-operative risk. Therefore, older adults may benefit from the Comprehensive Geriatric Assessment (CGA) that allows clinicians to evaluate several aspects of elderly life, such as depression and cognitive disorders, social status, multi-morbidity, frailty, geriatric syndromes, nutritional status, and polypharmacy. Despite the recognized challenges in applying the CGA, it may provide a realistic risk assessment for post-operative complications and suggest a tailored peri-operative treatment plan for older adults, including pre-operative optimization strategies. The older adults’ pre-operative examination should not be considered a mere stand-alone, that is, an independent stage of the surgical pathway, but rather a vital step toward a personalized therapeutic approach that may involve professionals from different clinical fields. The aim of this review is to revise the evidence from the literature and highlight the most important items to be implemented in the pre-operative evaluation process in order to identify better all elderly patients’ needs.
Anesthesia and perioperative pain relief in the frail elderly patient
Authors: Van Zundert Tom C.R.V. , Gatt Stephen P , van Zundert André A.J. 
Published: August 2023

ABSTRACT
Demand for anesthesia and analgesia for the frail elderly is continuously increasing as the likelihood of encountering very elderly, very vulnerable, and very compromised patients has, ever so subtly, increased over the last three decades. The anesthesiologist has, increasingly, been obliged to offer professional services to frail patients. Fortunately, there has been a dramatic improvement in medications, methods of drug delivery, critical monitoring, and anesthesia techniques. Specific methodologies peculiar to the frail are now taught and practiced across all anesthesia subspecialties. However, administering anesthesia for the frail elderly is vastly different to giving an anesthetic to the older patient. Frail patients are increasingly cared for in specialized units—geriatric intensive therapy units, post-acute care services, palliative, hospices, and supportive care and aged care facilities. Several medications (e.g., morphine-sparing analgesics) more suited to the frail have become universally available in most centers worldwide so that best-practice, evidence-based anesthesia combinations of drugs and techniques are now increasingly employed. Every anesthetic and pain management techniques in the frail elderly patient are going to be discussed in this review.
Pengaruh Pemakaian Lensa Blue Cut Terhadap Kenyamanan Pemakaian Kacamata Di Optik Jaya Pasaman Barat
Authors: Suryanta Dolly imam 
Published: August 2023

Gangguan penglihatan membuat sesorang harus menggunakan alat bantu penglihatan agar penglihatan menjadi jelas. Berbagai cara dilakukan orang, seperti menggunakan kacamata, lensa kontak bahkan operasi lasik. Penambahan lensa blue cut pada kacamata pada umumnya digunakan untuk membantu penglihatan manusia terhadap kelemahan mata karena rabun atau alasan penglihatan lainnya dan melindungi mata dari sinar UV. Tujuan penelitian ialah (1) untuk mengetahui pengaruh pemakaian lensa blue cut terhadap kenyamanan pemakaian kacamata di optik jaya Pasaman Barat (2) Untuk mengetahui keunggulan lensa blue cut terhadap kesehatan mata bagi pemakai kacamata Di Optic Zal Pondok Padang.
Jenis penelitian yang digunakan adalah deskriptif kuantitatif, proses penelitian dilakukan wawancara dengan menyebarkan kuesioner, penelitian ini bertujuan untuk mendapatkan gambaran mengenai pengaruh pemakaian lensa blue cut terhadap kenyamanan pemakaian kacamata di optik jaya Pasaman Barat. Populasi dalam penelitian ini adalah seluruh pasien usia dini yang mengalami kelainan refraksi penelitian yang berjumlah 30 Orang. Mengingat populasi yang diteliti kurang dari 100 orang maka sampel dalam penelitian ini adalah seluruh konsumen optik jaya Pasaman Barat berjumlah 30 Orang. Penelitian dilakukan kepada pasien usia dini di Optik jaya Pasaman Barat.
Hasil penelitian diperoleh bahwa responden bahwa 61,7% dari responden mengetahui pengaruh pemakaian lensa blue cut terhadap kenyamanan pemakaian kacamata, ini disebabkan karena kurang mengetahui dampak dari sinar UV terhadap kesehatan mata dan 60,1% lensa blue cut memiliki keunggulan untuk menjaga kesehatan mata.
Berdasarkan hasil penelitian ini ditarik kesimpulan bahwa Sebanyak 61,7% Respon mengetahui pengaruh pemakaian lensa blue cut terhadap kenyamanan pemakaian kacamata di optik jaya Pasaman Barat. Hal ini disebabkan karena kurangnya pengetahuan responden terhadap dampak dari sinar biru terhadap kesehatan mata. Berdasarkan hasil penelitian pengaruh pemakaian lensa blue cut terhadap kenyamanan pemakaian kacamata di optik jaya Pasaman Barat diperoleh hasil penelitian bahwa sebanyak 60,7% responden mengetahui keunggulan dari kacamata lensa blue cut dan disarankan kepada masyarakat Pada saat berhadapan langsung pasien harus memakai lensa anti radiasi yang di kenal dengan lensa blueray.
Rachel Vennya Persuasive Communication Strategy to Improve Her Personal Branding on Instagram
Authors: Putri Anisqha Maia , Agustine Yohan  Chandra , Wahyunengsih Wahyunengsih 
Published: August 2023

The purpose of this study is to identify the types of persuasive communication strategies used by Rachel Vennya in the content uploaded on her personal Instagram account. Second, to know the characteristics of Personal branding. This research uses a qualitative approach that aims to explore something in depth. This qualitative research contains a literature review, theoretical concepts related to the research problem, namely the problem of using persuasive strategies and personal branding in building personal branding. The results show that Rachel Vennya uses persuasive communication strategies, namely psychodynamic strategies, sociocultural strategies and the meaning constructions. Rachel Vennya has also applied the characteristics of a personal branding, namely uniqueness, relevance, and consistency.
Earth-system-model evaluation of cloud and precipitation occurrence for supercooled and warm clouds over the Southern Ocean's Macquarie Island
Authors: Stanford McKenna W. , Fridlind Ann M. , Silber Israel , Ackerman Andrew S. , Cesana Greg , Mülmenstädt Johannes , Protat Alain , Alexander Simon , McDonald Adrian 
Published: August 2023

Abstract. Over the remote Southern Ocean (SO), cloud feedbacks contribute substantially to Earth system model (ESM) radiative biases. The evolution of low Southern Ocean clouds (cloud-top heights < ∼ 3 km) is strongly modulated by precipitation and/or evaporation, which act as the primary sink of cloud condensate. Constraining precipitation processes in ESMs requires robust observations suitable for process-level evaluations. A year-long subset (April 2016–March 2017) of ground-based profiling instrumentation deployed during the Macquarie Island Cloud and Radiation Experiment (MICRE) field campaign (54.5∘ S, 158.9∘ E) combines a 95 GHz (W-band) Doppler cloud radar, two lidar ceilometers, and balloon-borne soundings to quantify the occurrence frequency of precipitation from the liquid-phase cloud base. Liquid-based clouds at Macquarie Island precipitate ∼ 70 % of the time, with deeper and colder clouds precipitating more frequently and at a higher intensity compared to thinner and warmer clouds. Supercooled cloud layers precipitate more readily than layers with cloud-top temperatures > 0 ∘C, regardless of the geometric thickness of the layer, and also evaporate more frequently. We further demonstrate an approach to employ these observational constraints for evaluation of a 9-year GISS-ModelE3 ESM simulation. Model output is processed through the Earth Model Column Collaboratory (EMC2) radar and lidar instrument simulator with the same instrument specifications as those deployed during MICRE, therefore accounting for instrument sensitivities and ensuring a coherent comparison. Relative to MICRE observations, the ESM produces a smaller cloud occurrence frequency, smaller precipitation occurrence frequency, and greater sub-cloud evaporation. The lower precipitation occurrence frequency by the ESM relative to MICRE contrasts with numerous studies that suggest a ubiquitous bias by ESMs to precipitate too frequently over the SO when compared with satellite-based observations, likely owing to sensitivity limitations of spaceborne instrumentation and different sampling methodologies for ground- versus space-based observations. Despite these deficiencies, the ESM reproduces the observed tendency for deeper and colder clouds to precipitate more frequently and at a higher intensity. The ESM also reproduces specific cloud regimes, including near-surface clouds that account for ∼ 25 % of liquid-based clouds during MICRE and optically thin, non-precipitating clouds that account for ∼ 27 % of clouds with bases higher than 250 m. We suggest that the demonstrated framework, which merges observations with appropriately constrained model output, is a valuable approach to evaluate processes responsible for cloud radiative feedbacks in ESMs.
Styl kierowania jako wyznacznik zarządzania lokalami gastronomicznymi typu weselnego na przykładzie Duet w Przeworsku
Authors: Cyrek Magdalena , Fedan Roman 
Published: August 2023

Styl kierowania jako wyznacznik zarządzania lokalami gastronomicznymi typu weselnego na przykładzie Duet w Przeworsku.
Efektywne kierowanie personelem w firmie stanowi coraz większe wyzwanie dla przełożonych. Od nich zależy, jaki styl kierowania będzie stosowany w ich przedsiębiorstwie. W artykule zaprezentowano analizę dorobku literatury dotyczącego stylów kierowania oraz wyniki badań własnych przeprowadzanych w organizacji.
Wśród przyjętych celów za najistotniejszy uznano:
– ukazanie metod wpływu przełożonego na skuteczną pracę personelu tak, aby przedsiębiorstwo osiągnęło sukces,
Dla zrealizowania pełnej problematyki pracy sformułowano także hipotezę badawczą:
– efektywna i sprawna kadra zarządzająca otwarta na współpracę z personelem, wpływa na zapewnienie wysokiego poziomu bezpieczeństwa i zwiększenie sprawności przedsiębiorstwa.
Materiał empiryczny w pełni potwierdza przyjęty cel i założenia badawcze oraz formułuje określone wnioski końcowe.
SOSIALISASI INFORMASI GIZI REMAJA DALAM MENINGKATKAN KESEHATAN DI MASA PANDEMI COVID-19 TERKAIT ANEMIA DAN DIET RENDAH SERAT DI DESA SEMBUNGAN KASIHAN BANTUL YOGYAKARTA
Authors: Riskha Dora Candra Dewi  , Christa Dyah Utami  , Descha Giatri Cahyaningrum  
Published: August 2023

Perilaku hidup sehat perlu ditingkatkan dalam mencegah penularan Covid 19 yaitu berolahraga, tidak merokok dan mengonsumsi makanan sehat dan bergizi. Desa Sembungan Kasihan Bantul Yogyakarta memiliki populasi sebanyak 1299 jiwa dimana tingkat pendidikan masyarakat yang masih rendah sehingga sangat rentan dalam pemahaman akan gizi yang baik dimana sebagai salah satu senjata utama untuk menangkal penyebaran Covid 19. Metode Pelaksanaan berupa sosialisasi kepada remaja disampaikan dalam bentuk ceramah yang didukung dengan program power point dan leaflet untuk memudahkan penyampaian informasi. Berdasarkan kegiatan sosialisasi yang telah dilaksanakan, dapat disimpulkan bahwa sosialisasi tentang anemia serta diet rendah serat sangat diperlukan bagi masyarakat khsusnya masyarakat Desa Sembungan yang minim fasilitas pendidikan dan kesehatan. Dan teknik penyampaian sosialisasi terhadap kondisi dan karakter peserta menjadi kunci utama tingkat keberhasilan masuknya materi di pemahaman peserta.