bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is robotic assistance an added value in minimally invasive mitral valve surgery? A meta-analysis from propensity score–matched series
Authors: Jegaden Olivier , Al Shamry Adel , Ashafy Salah , Mahdi Alhaitham , Eker Armand 
Published: March 2023

Objectives There is still ongoing debate about the benefits of robotic assistance (R-MVS) in comparison with video assistance (V-MVS) in minimally invasive mitral valve surgery. This study aims to update the current evidence. Methods Three propensity score–matched studies published from 2011 to 2021 were included with a total of 1193 patients operated on from 2005 (R-MVS: 536, V-MVS: 657). Data regarding early mortality, postoperative event, and time-related outcomes were extracted and submitted to a meta-analysis using weighted random-effects modeling. Results The incidence of early mortality, stroke, renal failure, conversion, atrial fibrillation, and prolonged ventilation were similar, all in the absence of heterogeneity. Reoperation for bleeding (odds ratio [OR]: 0.36, 95% confidence interval [CI] 0.16–0.81, p = 0.01) and the need for blood transfusion (OR: 0.30, 95% CI, 0.20–0.56, p = 0.001) were significantly lower in V-MVS group. Regarding time-related outcomes, there was evidence for important heterogeneity of treatment effect among the studies. Operative times were longer in R-MVS: differences in means were 20.7 min for cross-clamp time (95% CI, 9.07–32.3, p = 0.001), 20.7 min for cardiopulmonary bypass time (95% CI, 2.5–38.9, p = 0.03) and 40.2 min for total operative time (95% CI, 24.5–55.8, p < 0.001). Intensive care unit stay and hospital stay were reported in one study, and longer after R-MVS compared to V-MVS; the differences in means were 0.17 days ( p = 0.005) and 0.6 days ( p = 0.017), respectively. Total cost of both procedures was reported in an additional dedicated propensity score–matched series including 448 patients; it was 21% higher for R-MVS than for V-MVS. Conclusions This meta-analysis showed excellent outcomes of both video and robotic techniques with low incidence of morbidity and mortality. However, there is no evidence for an added value of robotic assistance in comparison with video assistance; the drawbacks of mini access are reported higher regardless the induced over cost.
How transdisciplinary integration, creativity and student motivation interact in three STEAM projects for gifted education?
Authors: Lage-Gómez Carlos , Ros Germán 
Published: March 2023

The study analyses the relationship between transdisciplinary integration, creativity and student motivation in three STEAM projects. It has been carried out over 3 years in a programme for gifted students. 152 students (11–12 years old), five teachers and four external professionals participated. The projects included a variety of scientific, humanistic and artistic activities, together with outings, the collaboration of experts and the creation of a transdisciplinary art-based final products. The research was carried out through the analysis of qualitative data (interviews, video-recordings, participant observation) using Atlas.ti8 within the framework of Activity Theory and statistical analysis of questionnaires. It shows how the transdisciplinary integration favoured a complex approach to knowledge with an essential role of the artistic-based transdisciplinary final products and fostered a plural approach to creativity. The active participation of the students favoured their motivation and involvement. The significant correlation between creativity, student motivation and transdisciplinary integration emerges as a key element in the STEAM projects implemented.
Iliopsoas haematoma during extracorporeal membrane oxygenation: A registry report from the COVID-19 critical care consortium across 30 countries
Authors: Taniguchi Hayato , Rätsep Indrek , Heinsar Silver , Liu Keibun , Cespedes Marcela , Suen Jacky Y , Li Bassi Gianluigi , Fraser John F , Jacobs Jeffrey P , Peek Giles J 
Published: March 2023

Introduction Iliopsoas haematoma (IPH) during extracorporeal membrane oxygenation (ECMO) is a rare bleeding complication that can be fatal due to its progression to abdominal compartment syndrome, but its incidence and risk factors are not well known. We have previously reported an IPH incidence rate of 16% in Japan. Among possible reasons for this high incidence, ethnicity has been hypothesised to play a role. Therefore, we used an international multi-centre cohort registry to test this hypothesis by determining the incidence rate of IPH. Methods This study was performed using the COVID-19 Critical Care Consortium database, conducted in 30 countries across five continents between 3 January 2020, and 20 June 2022. Results Overall, 1102 patients received ECMO for COVID-19-related acute respiratory distress syndrome. Of them, only seven were reported to have IPH, indicating an incidence rate of 0.64%, with comparable rates between the countries. The IPH group tended to have a higher mortality rate (71.4%) than the non-IPH group (51%). Conclusions Overall incidence of IPH in the studied COVID-19 ECMO cohort was 0.64%. Most cases were reported from Japan, Belgium, and Italy. In our study, this rare complication did not appear to be confined to Asian patients. Due to the high fatality rate, awareness about the occurrence of IPH should be recognised.
The utility of sepsis scores for predicting blood stream infections in extracorporeal membrane oxygenation
Authors: Lee Daniel G , Sobieszczyk Michal J , Barsoumian Alice E , Marcus Joseph E 
Published: March 2023

Introduction Extracorporeal membrane oxygenation (ECMO) is an increasingly used modality of life support with high risk for nosocomial infections. The accuracy of sepsis prediction tools in identifying blood stream infections (BSI) in this population is unknown as measurement of multiple variables commonly associated with infection are altered by the circuit. Methods This study compares all blood stream infections for patients receiving ECMO between January 2012 and December 2020 to timepoints when blood cultures were negative using the Sequential Organ Failure Assessment (SOFA), Logistic Organ Dysfunction Score (LODS), American Burn Association Sepsis Criteria (ABA), Systemic Inflammatory Response Syndrome (SIRS) scores. Results Of the 220 patients who received ECMO during the study period, 40 (18%) had 51 blood stream infections and were included in this study. Gram-positive infections composed 57% ( n = 29) of infections with E. faecalis ( n = 12, 24%) being the most common organism isolated. There were no significant differences in sepsis prediction scores at the time of infection compared to infection-free time points for SOFA (median (IQR) 7 (5–9) vs. 6 (5–8), p = 0.22), LODS (median (IQR) 12 (10–14) vs. 12 (10–13), p = 0.28), ABA (median (IQR) 2 (1–3) vs. 2 (1–3) p = 0.75), or SIRS (median (IQR) 3 (2–3) vs. 3 (2–3), p = 0.20). Conclusions Our data shows that previously published sepsis scores are elevated throughout a patient’s ECMO course, and do not correlate with bacteremia. Better predictive tools are needed to determine the appropriate timing for blood cultures in this population.
Assessment of Rainfall Risk in a Financial Perspective: An Application to the Wine Industry
Authors: Franzoni Simona , Pelizzari Cristian 
Published: March 2023

Climate change is an increasingly critical phenomenon in agriculture, which includes wine production. Rainfall appears to be extremely important for wine production; however, it can become a disaster in large quantities. Given the nature of external risk to the enterprise, rainfall financial risk, that is, the risk of decreasing revenues due to persistent rain is difficult to forecast, manage and monitor. Therefore, it is crucial for wineries to assess such a risk to safeguard their business performances. This study adds to the literature on wine, weather and risk assessment by developing an assessment method of rainfall financial risk for small- and medium-sized wine enterprises. In particular, starting from the result of applying the proposed method, that is the assessment, or not, of rainfall financial risk, it is possible to make recommendations to a winery on the adoption, or not, of mitigation measures of such a risk with the final goal of preserving profitability and solvability. The proposed method was empirically applied to a selected group of wineries located near Lake Garda (Northern Italy), during the period 2010–2019.
Safety and efficacy of cryopexy during pars Plana vitrectomy in rhegmatogenous retinal detachment
Authors: Loiudice Pasquale , Pintor Emanuele Siotto , Tronci Claudia , Tatti Filippo , Casini Giamberto , Figus Michele , Demarinis Giuseppe , Peiretti Enrico 
Published: March 2023

Purpose To evaluate efficacy and safety of intraoperative cryoretinopexy in cases of rhegmatogenous retinal detachment (RRD) Methods In this retrospective, interventional case series, we review the medical records of 85 consecutive cases of RRD treated with pars plana vitrectomy and gas tamponade, without the use of perfluorocarbon liquids. Baseline best-corrected visual acuity, intraocular pressure, number and location of retinal breaks, location and extension of retinal detachment, duration of symptoms, macula status, presence, and grade of proliferative vitreoretinopathy (PVR) were registered. Follow-up visits were at 1 day, 15 days, 1 month and 3 months. Anatomical and functional outcomes and any adverse event were recorded. Results Primary anatomical success was obtained in 82/85 patients (96%). During the postoperative period, PVR was observed in 4/85 cases (4.7%), 3 of whom developed recurrence of retinal detachment. 7/85 (8.2%) patients developed ocular hypertension. We built a model of logistic regression including age, sex, lens status, macula status, number of quadrants involved, number of ruptures and duration of symptoms. None of the variables considered was found to be a predictor of postoperative PVR development. Symptom's duration (β = 0.429; 95% CI = 0.009–0.023; P < 0.001) and preoperative BCVA (β = 0.273; 95% CI = 0.034–0.184; P = 0.005) were predictors for final BCVA. Conclusion These findings emphasize the safety and efficacy of the use of intraoperative cryotherapy, associated with PPV and gas tamponade, for the management of uncomplicated RRDs.
Sufficiently small rotations of Lagrange’s gyro
Authors: Ismail AI , Amer TS , Amer WS 
Published: March 2023

In this study, the motion of Lagrange’s gyro about its fixed point in the presence of a perturbed torque, a gyroscopic torque, and a varied restoring one is searched. We assume sufficiently small angular velocity components in the direction of the principal axes that differ from the dynamical symmetry one and a restoring torque that is considered to be greater than the perturbing one. In this manner, we replace the familiar small parameter that was used in previous works with a large one. In such cases, the gyro equations for motion (EOM) are formulated in the form of a two-degrees-of-freedom (DOF) autonomous system. We average the obtained system to get periodic solutions and motion’s geometric interpretation of the problem using the large parameter. The regular precession and the pure rotation of the motion are obtained. A numerical study is evaluated for asserted the used techniques and showed the influence of the changing parameters of motion on the gyro behavior. The trajectories of the motions and their stabilities are discussed and analyzed. The novelty of this work lies in how to adapt the method of large parameter (MLP) to solve the rigid body problem, especially since it has been assumed initially that its angular velocity or its initial energy are very small. MSC (2000): 70E20, 70E17, 70E15, 70E05
The Use of Three-Dimensional Printing in Cardiac Structural Disease: A Review
Authors: Hornstein Gabrielle , Diep Calvin , Masson Jean-Bernard , Potvin Jeannot , Gobeil Jean-François , Noiseux Nicolas , Forcillo Jessica 
Published: March 2023

Objective: Three-dimensional printing (3DP), or additive fabrication, is a process in which a physical 3D model is created using a multitude of 2-dimensional images. This process has been applied to numerous surgical subspecialties with growing interest for the use of 3DP in adult structural heart disease. This scoping review evaluates the use of 3DP in transcatheter and surgical aortic and mitral valve interventions as well as left atrial appendage occlusion in terms of its practical and clinical application. Methods: Articles were identified through PubMed and Embase using MeSH search terms as well as independent searches. A total of 645 articles were screened, and 37 were retained for qualitative analysis. Results: Operative planning was coded in 100% of articles, complication prevention in 43%, medical education in 5.4%, patient education in 0%, and simulation in 5.4%. Conclusions: The main uses of 3DP in acquired structural heart disease are centered around operative planning and complication prevention, with moderate use regarding surgical simulation and infrequent use regarding medical and/or patient education. Although patient anatomy varies greatly, deploying 3DP as a large-scale tool remains a possibility. The more 3D models are made, the more can be learned about demographic subsets of patient populations. Due to the lack of standard operating procedures for the creation of 3DP models, the cost-effectiveness of these models is hard to determine and likely center specific. More research into this facet could inform centers that wish to implement this tool.
Hydrogen gas treatment improves survival in a rat model of crush syndrome by ameliorating rhabdomyolysis
Authors: Yumoto Tetsuya , Aokage Toshiyuki , Hirayama Takahiro , Yamamoto Hirotsugu , Obara Takafumi , Nojima Tsuyoshi , Naito Hiromichi , Nakao Atsunori 
Published: March 2023

Objectives Crush syndrome (CS) is characterized by a systemic manifestation of traumatic rhabdomyolysis, leading to multiple organ dysfunction and death. Ischemia-reperfusion (IR) injury is commonly responsible for systemic response. Extending studies have shown that hydrogen gas treatment ameliorated IR injury in numerous experimental models; however, its effect on CS has not been well examined. This study aimed to investigate the effects of hydrogen gas inhalation following crush injury in an experimental model of CS. Methods Male Sprague-Dawley rats were subjected to experimental CS by applying a total of 3.0 kg weight to both hindlimb under general anesthesia for 6 h. Immediately after decompression, the animals were randomly placed in a gas chamber filled with either air or 1.3% hydrogen gas. Animals were sacrificed 18 h or 24 h following gas exposure for non-survival studies or for survival study, respectively. Results The rats with hydrogen treatment ( n = 6) had a higher 24-h survival than the rats with air treatment ( n = 9) (100% vs. 44%, p = 0.035). Lactate concentrations (2.9 ± 0.2 vs. 2.2 ± 0.2 mmol/L, p = 0.040) and creatine kinase (34,178 ± 13,580 vs. 5005 ± 842 IU/L, p = 0.016) were lower in the hydrogen group compared with the air group 18 h after decompression ( n = 4 in the air group, and n = 5 in the H2 group). Histological analysis revealed that the damage to the rectus femoris muscle and kidney appeared to be ameliorated by hydrogen treatment. Conclusion Hydrogen gas inhalation may be a promising therapeutic approach in the treatment of CS.
Failure rates and analysis of risk factors for percutaneous A1 pulley release of trigger digits
Authors: Jeon Neunghan , Yoo Sang Gil , Kim Seong Kyong , Park Min Jong , Shim Jae Woo 
Published: March 2023

This study aimed to identify the rates and risk factors for failure of percutaneous A1 pulley release. We retrospectively analysed patients who underwent percutaneous A1 pulley release between 2015 and 2019. We defined failure as (1) pain or discomfort at the final follow-up, (2) when open release or revision percutaneous release was performed, or (3) when steroid injections were administered three or more times for symptom control. A total of 331 digits from 251 patients were included. The mean follow-up duration was 47 months (minimum 24 months). Complete resolution was achieved in 287 cases (87%), but 21% required steroid injection before symptoms settled. There was failure in 44 cases (13%). Involvement of the index, middle and ring fingers was significantly different between the successful and failure groups. Percutaneous A1 pulley release has a long-term success rate of 87%. The failure rate was higher when the procedure was performed on the index, middle or ring fingers. Level of evidence: III
Latent change models of lifestyle in acute coronary syndrome patients: Are lifestyle changes associated with resilience changes?
Authors: Greco Andrea , Adorni Roberta , De Matteis Chiara , D’Addario Marco , Fattirolli Francesco , Franzelli Cristina , Giannattasio Cristina , Luyckx Koen , Steca Patrizia 
Published: March 2023

This study aimed to examine the role of resilience resources in patients' lifestyle changes after the first Acute Coronary event. 275 Italian patients (84.0% men; mean age = 57.5, SD = 7.9) participated in a longitudinal study. Resilience resources (Self-esteem, Dispositional Optimism, Sense of Coherence – SOC, General and Disease-specific Self-efficacy), and lifestyles (diet, physical activity, and smoking) were assessed twice (at baseline and after 6 months). Path analysis using latent change models was performed to model the combined effect of levels and changes of the resilience resources over lifestyle changes. Patients with strong SOC at baseline were less prone to smoke and more prone to decrease smoking; enhancement in SOC was associated with a smoking decrease. High Disease-specific Self-efficacy at baseline was associated with an improvement in all lifestyles; enhancement in Disease-specific Self-efficacy predicted an increase in physical activity. Findings underline the need to design psychological interventions that promote patients' Disease-specific Self-efficacy and SOC.
Paper 08: Long Term Survivorship and Outcomes of Patients Undergoing Capsular Repair and Primary Hip Arthroscopy for Femoroacetabular Impingement Syndrome
Authors: Domb Benjamin , Lee Michael , Jimenez Andrew , Maldonado David , Lall Ajay , Harris Wallace 
Published: March 2023

Objectives: The purpose of this study is to report minimum 10-year survivorship and patient-reported outcomes (PROs) following primary hip arthroscopy with capsular repair for FAIS and to compare outcomes of patients undergoing capsular repair to capsular release. Methods: Data were prospectively collected and retrospectively reviewed on all patients undergoing primary hip arthroscopy with capsular repair between October 2008 and February 2011. Survivorship was defined as a non-conversion to total hip arthroplasty (THA). Patients with minimum 10-year follow-up for the modified Harris Hip Score (mHHS), Nonarthritic Hip Score (NAHS), and Visual Analog Scale for pain (VAS). If available, preoperative and minimum 10-year follow-up for the Hip Outcome Score—Sports Specific Subscale (HOS-SSS) were reported. Patients with ipsilateral hip surgery, worker’s compensation, Tönnis osteoarthritis grade > 1, and hip dysplasia (lateral center-edge angle < 25°) were excluded. Survivorship defined by non-conversion to THA, PROS, and clinical benefit (minimal clinically important difference (MCID) and patient acceptable symptomatic state (PASS)) were reported. An additional propensity-matched sub-analysis comparing patients undergoing capsular repair with patients undergoing capsular release over the age of 40 with acetabular labrum articular disruption ≥ 2 was performed. Results: 145 (130 patients) out of 180 eligible hips (165 patients) had minimum 10-year follow-up (80.6%). 126 hips (86.9%) were female, and 19 hips (13.1%) were male. The average patient age was 30.3 ± 12.9 years. The survivorship rate was 91.0% at minimum 10-year follow-up. The cohort experienced significant improvement (P < 0.001) in the mHHS, NAHS, HOS-SSS, and VAS for pain. Additionally, the cohort achieved high rates of PASS for the mHHS (89.8%), and high rates of the MCID for the mHHS (82.4%) and VAS for pain (80.6%). 29 capsular repair hips were matched to 81 capsular release hips. Both groups experienced significant improvement in all PROs, but there was a higher conversion to THA rate in the release group (P < 0.05). Conclusions: Patients undergoing primary hip arthroscopy with capsular repair experienced a high rate of survivorship of 91.0% at minimum 10-year follow-up. Patients that did not convert to THA saw favorable improvements in PROs and achieved high rates of clinical benefit. In the subanalysis, patients undergoing capsular repair demonstrated higher rates of survivorship.
Paper 09: Revision rate following primary hip arthroscopy in patients given prophylactic oral losartan for the prevention of post-surgical fibrosis versus no losartan
Authors: Su Chuck , Day Hannah , Comfort Spencer , Briggs Karen , Huard Johnny , Philippon Marc 
Published: March 2023

Objectives: To evaluate whether postoperative treatment with Losartan decreased the revision rate in patients undergoing primary hip arthroscopy. Methods: Patients underwent primary hip arthroscopy with labral repair and CAM osteoplasty and rim trimming between 2012 and 2017. Patients who underwent microfracture, labral debridement or reconstruction, core decompression, ligamentous teres repair or reconstruction, or capsular reconstruction were excluded. Losartan was added to all patients’ post-operative protocol in December 2015. Patients who underwent hip arthroscopy prior to November 2015 were included in the no-Losartan group (NOLOS) and patients who had arthroscopy between December 2015 and Dec 2017 were included in the losartan group (LOS). Results: Of the 964 cases, follow-up was obtained on 673 patients (70%). There were 405 patients in the NOLOS group and 268 in the LOS group. There was no difference in gender distribution (P=0.128) between groups. The LOS group was significantly older (36.6 ±13 years) compared to the NOLOS group (34.1±11)(p=0.012). Average follow-up in the NOLOS group was 5.8±2 years and was 4.1±1 years in the LOS group. Revision hip arthroscopy was required in 35 (8.6%) patients in the NOLOS group and 6 (2.2%) patients in the LOS group(p=0.001). There was no difference in age between those patients who required revision (32±11 years) and those who did not(35±12 years)(p=0.137). Conclusions: The prevalence of revision hip arthroscopy was significantly lower (2.2%) in patients who took Losartan as part of their post-operative protocol compared to those who did not (8.6%). Reduction in the need for revision hip arthroscopy can improve patient outcomes and reduce healthcare dollars spent.