bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictive value of hyperglycemia on infection in critically ill patients with acute pancreatitis
Authors: Jin Yingzhi , Tao Shaoyu , Yu Guang , Li Chengyi , Hu Zanqun , Jiang Longjian 
Published: March 2023

AbstractTo analyze the predictive value of hyperglycemia on the extrapancreatic infection (EPI) and infected pancreatic necrosis (IPN) of severe patients with acute pancreatitis (AP). We enrolled 234 patients with acute pancreatitis admitted to the intensive care unit (ICU) of the Second Affiliated Hospital of Nanchang University from July 2017 to July 2022 for a retrospective cohort study. We collected maximum blood glucose values three times after admission to the ICU within 120 h (Glu1: 0–24 h, Glu2: 24–48 h, Glu3: 48–120 h), the levels of leucocyte, blood urea nitrogen (BUN), C-reactive protein (CRP), procalcitonin (PCT), and albumin within 24 h after admission to the ICU, and the BISAP and SIRS scores of all patients within 24 h. EPI was taken as the primary outcome indicator and IPN as the secondary outcome indicator. The accuracy of blood glucose values in predicting acute pancreatitis infection was measured by the area under the curve (AUC). A total of 56 patients appeared EPI. Univariate analysis showed that Glu3 was associated with IPN in critically ill patients with AP. Multivariate logistic regression analysis showed that Glu2, Glu3, and SIRS > 48 h were associated with EPI in critically ill patients with AP. The AUCs of Glu2 and Glu3 to predict EPI were 0.805(95%CI: 0.717–0.892) and 0.782(95%CI: 0.685–0.878), respectively, and the cutoff values were 12.60 mmol/L and 14.75 mmol/L, respectively. The AUC of Glu2 combined with Glu3 to predict EPI was 0.812(0.725–0.899). The maximum blood glucose on Day2-5 after admission to the ICU can predict infection in critically ill patients with AP. There are differences in etiology while glucose predicting infection. Patients with hypertriglyceridemia AP need to intervene blood glucose levels more actively and earlier, and control it more strictly.
Atrial fibrillation as a new prognosis factor in chronic patients after hospitalization: the CHRONIBERIA index
Authors: Suarez-Dono Javier , Novo-Veleiro Ignacio , Gude-Sampedro Francisco , Marinho Ricardo , Xavier-Pires Sara , Rocha Diana , Araújo-Correia João , Moreira Cecília , Beires Francisca , Pérez Danay , David Filipa , Vasco-Barreto J. , Del Corral-Beamonte Esther , Piñeiro-Fernández Juan-Carlos , Casariego-Vales Emilio , Diez-Manglano Jesús , Pose-Reino Antonio 
Published: March 2023

AbstractA collaborative project in different areas of Spain and Portugal was designed to find out the variables that influence the mortality after discharge and develop a prognostic model adapted to the current healthcare needs of chronic patients in an internal medicine ward. Inclusion criteria were being admitted to an Internal Medicine department and at least one chronic disease. Patients’ physical dependence was measured through Barthel index (BI). Pfeiffer test (PT) was used to establish cognitive status. We conducted logistic regression and Cox proportional hazard models to analyze the influence of those variables on one-year mortality. We also developed an external validation once decided the variables included in the index. We enrolled 1406 patients. Mean age was 79.5 (SD = 11.5) and females were 56.5%. After the follow-up period, 514 patients (36.6%) died. Five variables were identified as significantly associated with 1 year mortality: age, being male, lower BI punctuation, neoplasia and atrial fibrillation. A model with such variables was created to estimate one-year mortality risk, leading to the CHRONIBERIA. A ROC curve was made to determine the reliability of this index when applied to the global sample. An AUC of 0.72 (0.7–0.75) was obtained. The external validation of the index was successful and showed an AUC of 0.73 (0.67–0.79). Atrial fibrillation along with an advanced age, being male, low BI score, or an active neoplasia in chronic patients could be critical to identify high risk multiple chronic conditions patients. Together, these variables constitute the new CHRONIBERIA index.
Study on thermal insulation cement and its thermal insulation characteristics for geothermal wells
Authors: Zhou Wei , Wang Chengwen , Meng Renzhou , Chen Zehua , Lu Haoxin , Chi Jialun 
Published: March 2023

AbstractReducing the heat loss in wellbore is the key for efficient development of geothermal resource. It is a reliable solution to establish a long-term stable wellbore with good thermal insulation through cementing. In this paper, the cement-based composite thermal insulation material was prepared by using cement as the cementing material, hollow glass beads, foaming agent and stabilizer as main raw materials, and other conventional admixtures. Foams and hollow glass beads can introduce gas with low thermal conductivity into cement, so as to improve the thermal insulation of composite material. Foams are produced by chemical forming process, using foaming agent, which is prepared according electrochemistry and thermodynamics, and the foam stabilizer helps foam distribute in cement slurry stably and uniformly. 10–13% hollow glass beads can significantly reduce the thermal conductivity of hardened cement, without significant adverse effects on the rheology and strength of the material. The thermal conductivity of the composite thermal insulation material can be as low as 0.2998 W·(m·K)−1, which is 62% lower than that of conventional cement, while the compressive strength is 6.10 MPa, meeting the engineering requirement. A thermal-conductivity prediction method is proposed correspondingly based on Maxwell model, and the prediction error of the newly established model is within 2%. This research can provide technical support for efficient development of geothermal resources.
Pre- and peri-natal hurricane exposure alters DNA methylation patterns in children
Authors: Kello Erin , Vieira Alexandre R. , Rivas-Tumanyan Sona , Campos-Rivera Maribel , Martinez-Gonzalez Karen G. , Buxó Carmen J. , Morou-Bermúdez Evangelia 
Published: March 2023

AbstractHurricane Maria was the worst recorded natural disaster to affect Puerto Rico. Increased stress in pregnant women during and in the aftermath of the hurricane may have induced epigenetic changes in their infants, which could affect gene expression. Stage of gestation at the time of the event was associated with significant differences in DNA methylation in the infants, especially those who were at around 20–25 weeks of gestation when the hurricane struck. Significant differences in DNA methylation were also associated with maternal mental status assessed after the hurricane, and with property damage. Hurricane Maria could have long lasting consequences to children who were exposed to this disaster during pregnancy.
Vole outbreaks may induce a tularemia disease pit that prevents Iberian hare population recovery in NW Spain
Authors: Rouco Carlos , Luque-Larena Juan José , Vidal Dolors , Mougeot François 
Published: March 2023

AbstractIberian hare populations have suffered severe declines during recent decades in Spain. Between 1970 and 1990s, a rapid increase in irrigation crop surface in NW Spain (Castilla-y-León region) was followed by a common vole massive range expansion and complete colonization of lowland irrigated agricultural landscapes from mountainous habitats. The subsequent large cyclic fluctuations in abundance of colonizing common voles have contributed to a periodic amplification of Francisellatularensis, the etiological agent that causes human tularemia outbreaks in the region. Tularemia is a fatal disease to lagomorphs, so we hypothesize that vole outbreaks would lead to disease spill over to Iberian hares, increasing prevalence of tularemia and declines among hare populations. Here we report on the possible effects that vole abundance fluctuations and concomitant tularemia outbreaks had on Iberian hare populations in NW Spain. We analysed hare hunting bag data for the region, which has been recurrently affected by vole outbreaks between 1996 and 2019. We also compiled data on F.tularensis prevalence in Iberian hares reported by the regional government between 2007 and 2016. Our results suggest that common vole outbreaks may limit the recovery of hare populations by amplifying and spreading tularemia in the environment. The recurrent rodent-driven outbreaks of tularemia in the region may result in a "disease pit" to Iberian hares: at low host densities, the rate of population growth in hares is lower than the rate at which disease-induced mortality increases with increased rodent host density, therefore, keeping hare populations on a low-density equilibrium. We highlight future research needs to clarify tularemia transmission pathways between voles and hares and confirm a disease pit process.
The normal impact stiffness of a debris-flow flexible barrier
Authors: Huo Miao , Zhou Jia-wen , Zhao Jiangtao , Zhou Hong-wei , Li Jidong , Liu Xing 
Published: March 2023

AbstractThis paper proposes a normal oriented impact stiffness of a three-supporting cable flexible barrier under a small pretension stress to estimate the structural load behaviour, and employs two categories of small-scale debris flows (coarse and fine) to explore the stiffness evolution through physical model experiments with high-speed photography and load sensing. Results suggest that the particle-structure contact is essential to the normal load effect. Coarse debris flow performs more frequent particle-structure contact and exerts evident momentum flux, while fine debris flows with few physical collisions impart much smaller one. The middle-sited cable that receives only tensile force from vertical equivalent cable-net joint system exhibits indirect load behaviour. The bottom-sited cable shows high load feedback due to the sum of direct contact of debris flow and tensile forces. The relationship between impact loads and maximum cable deflections can be explained by power functions according to quasi-static theory. The impact stiffness is not just affected by the particle-structure contact but by the flow inertia and particle collision effect. Savage number Nsav and Bagnold number Nbag manage to depict the dynamical effects on the normal stiffness Di. Experiments indicate that Nsav has positive linear correlation with the nondimensionalization of Di, whilst Nbag has positive power correlation with the nondimensionalization of Di. This idea is an alternative scope for the study on flow-structure interaction and may contribute to the parameter identification in numerical simulation of the debris flow-structure interaction and the optimization of the design standardization.
Albedo effects in the ER3BP with an oblate primary, a triaxial secondary and a potential due to belt
Authors: Singh Jagadish , Richard Tyokyaa K. 
Published: March 2023

AbstractWe have examined the effects of Albedo in the Elliptic Restricted Three-Body Problem (ER3BP) with an oblate primary, a triaxial secondary, and potential due to belt for the Earth–Moon system. We have found that as the perturbed parameters increases, the possible boundary regions of the primary come closer to one other, allowing particles to travel from one region to the next freely and possibly merge the permissible regions. Our study has revealed that the formation of triangular libration points depends on the Albedo effects, semi-major axis, the Eccentricity of the orbits, triaxiality, and the potential due to the belt. As the parameters mentioned above increase, the triangular positions $${L}_{4}$$

L
4

and $${L}_{5}$$

L
5

move towards the center of origin in cases 1, 2, 3, and 4 and away from the center of the origin in cases 5, 6, and 7. Considering the range of a stable and unstable libration point for the problem under study given as $$0<\mu <{\mu }_{c}$$

0
<
μ
<

μ
c

for stable libration points and $${\mu }_{c}\leq\mu \le \frac{1}{2}$$

μ
c

≤
μ
≤

1
2

for unstable libration points, our study has established that the triangular libration points are respectively stable and unstable for cases 1, 2, and 6 and cases 3, 4, 5, and 7. Our study has also revealed that each set of values has at least one characteristic complex root with a positive real part. Hence, the triangular libration points for the Earth–Moon system are unstable in the sense of Lyapunov. The Earth–Moon system's Poincare Surface of Section (PSS) has demonstrated that a slight change in the initial conditions, the semi-major axis, and the Eccentricity of the orbits have affected the system's behavior dramatically. Further, it is seen that a chaotic dynamical behavior of the system results into either regular or irregular orbits.
An integrative survival analysis and a systematic review of the cerebellopontine angle glioblastomas
Authors: Lasica Nebojsa , Arnautovic Kenan , Tadanori Tomita , Vulekovic Petar , Kozic Dusko 
Published: March 2023

AbstractGlioblastomas presenting topographically at the cerebellopontine angle (CPA) are exceedingly rare. Given the specific anatomical considerations and their rarity, overall survival (OS) and management are not discussed in detail. The authors performed an integrative survival analysis of CPA glioblastomas. A literature search of PubMed, Scopus, and Web of Science databases was performed per PRISMA guidelines. Patient data including demographics, clinical features, neuroimaging, management, follow-up, and OS were extracted. The mean age was 39 ± 26.2 years. The mean OS was 8.9 months. Kaplan–Meier log-rank test and univariate Cox proportional-hazards model identified hydrocephalus (log-rank, p = 0.034; HR 0.34; 95% CI 0.12–0.94; p = 0.038), chemotherapy (log-rank, p < 0.005; HR 5.66; 95% CI 1.53–20.88; p = 0.009), and radiotherapy (log-rank, p < 0.0001; HR 12.01; 95% CI 3.44–41.89; p < 0.001) as factors influencing OS. Hydrocephalus (HR 3.57; 95% CI 1.07–11.1; p = 0.038) and no adjuvant radiotherapy (HR 0.12; 95% CI 0.02–0.59; p < 0.01) remained prognostic on multivariable analysis with fourfold and twofold higher risk for the time-related onset of death, respectively. This should be considered when assessing the risk-to-benefit ratio for patients undergoing surgery for CPA glioblastoma.
The quality of vital signs measurements and value preferences in electronic medical records varies by hospital, specialty, and patient demographics
Authors: Jackson Niall , Woods Jessica , Watkinson Peter , Brent Andrew , Peto Tim E. A. , Walker A. Sarah , Eyre David W. 
Published: March 2023

AbstractWe aimed to assess the frequency of value preferences in recording of vital signs in electronic healthcare records (EHRs) and associated patient and hospital factors. We used EHR data from Oxford University Hospitals, UK, between 01-January-2016 and 30-June-2019 and a maximum likelihood estimator to determine the prevalence of value preferences in measurements of systolic and diastolic blood pressure (SBP/DBP), heart rate (HR) (readings ending in zero), respiratory rate (multiples of 2 or 4), and temperature (readings of 36.0 °C). We used multivariable logistic regression to investigate associations between value preferences and patient age, sex, ethnicity, deprivation, comorbidities, calendar time, hour of day, days into admission, hospital, day of week and speciality. In 4,375,654 records from 135,173 patients, there was an excess of temperature readings of 36.0 °C above that expected from the underlying distribution that affected 11.3% (95% CI 10.6–12.1%) of measurements, i.e. these observations were likely inappropriately recorded as 36.0 °C instead of the true value. SBP, DBP and HR were rounded to the nearest 10 in 2.2% (1.4–2.8%) and 2.0% (1.3–5.1%) and 2.4% (1.7–3.1%) of measurements. RR was also more commonly recorded as multiples of 2. BP digit preference and an excess of temperature recordings of 36.0 °C were more common in older and male patients, as length of stay increased, following a previous normal set of vital signs and typically more common in medical vs. surgical specialities. Differences were seen between hospitals, however, digit preference reduced over calendar time. Vital signs may not always be accurately documented, and this may vary by patient groups and hospital settings. Allowances and adjustments may be needed in delivering care to patients and in observational analyses and predictive tools using these factors as outcomes or exposures.
Safety level assessment of shield tunneling in water rich sandy pebble strata with large particle size
Authors: Yao Peiyi , Yu Ziwang , Lv Yan , Shi Bin , He Yuanyuan , Wang Hong , Liu Danna , Wei Shengda 
Published: March 2023

AbstractShield tunneling method is widely used in urban metro construction. The construction stability is closely related to the engineering geological conditions. Sandy pebble strata have a loose structure and low cohesion, resulting in great engineering-induced stratigraphic disturbance. Meanwhile, the high water-abundance and strong permeability are extremely detrimental to construction safety. It is of great significance to evaluate the dangerousness of shield tunneling in water-rich pebble strata with large particle size. In this paper, risk assessment of engineering practice is carried through with Chengdu metro project in China as a case study. Referring to the special engineering situations and assessment workload, seven evaluation indices, including compressive strength of pebble layer, boulder volume content, permeability coefficient, groundwater depth, grouting pressure, tunneling speed and tunnel buried depth are selected to establish an evaluation system. A complete risk assessment framework is established based on the cloud model, AHP and entropy weight method. Further, the measured surface settlement is taken as the risk degree characterization to verify the results. This study can provide reference for method selection and evaluation system establishment in the risk assessment of shield tunnel construction in water-rich sandy pebble strata, and contribute to proposing safety management in similar engineering projects.
Climate, landscape, and life history jointly predict multidecadal community mosquito phenology
Authors: Campbell Lindsay P. , Sallam Mohamed F. , Bauer Amely M. , Tavares Yasmin , Guralnick Robert P. 
Published: March 2023

AbstractPhenology of adult host-seeking female mosquitoes is a critical component for understanding potential for vector-borne pathogen maintenance and amplification in the natural environment. Despite this importance, long-term multi-species investigations of mosquito phenologies across environments and differing species’ life history traits are rare. Here we leverage long-term mosquito control district monitoring data to characterize annual phenologies of 7 host-seeking female mosquito species over a 20-year time period in suburban Illinois, USA. We also assembled data on landscape context, categorized into low and medium development, climate variables including precipitation, temperature and humidity, and key life history traits, i.e. overwintering stage and Spring–Summer versus Summer–mid-Fallseason fliers. We then fit linear mixed models separately for adult onset, peak abundances, and flight termination with landscape, climate and trait variables as predictors with species as a random effect. Model results supported some expectations, including warmer spring temperatures leading to earlier onset, warmer temperatures and lower humidity leading to earlier peak abundances, and warmer and wetter fall conditions leading to later termination. However, we also found sometimes complex interactions and responses contrary to our predictions. For example, temperature had generally weak support on its own, impacting onset and peak abundance timing; rather temperature has interacting effects with humidity or precipitation. We also found higher spring precipitation, especially in low development contexts, generally delayed adult onset, counter to expectations. These results emphasize the need to consider how traits, landscape and climatic factors all interact to determine mosquito phenology, when planning management strategies for vector control and public health protection.
The extent of windfarm infrastructures on recognised European blanket bogs
Authors: Chico Guaduneth , Clewer T. , Midgley N. G. , Gallego-Anex P. , Ramil-Rego P. , Ferreiro J. , Whayman E. , Goeckeritz S. , Stanton T. 
Published: March 2023

AbstractPeatland environments are the Earth’s largest terrestrial carbon store and have the potential to act as carbon sinks. However, the development of windfarms on peatlands is affecting their morphology, hydrology, ground-level climate conditions, carbon functions and vegetation, and long-term consequences still need to be assessed. Blanket bogs are a rare type of ombrotrophic peatland that are typical of oceanic areas with high precipitation and low temperatures. Their distribution has been mapped across Europe, where they are mainly located on hill summits where wind energy potential is higher, making them attractive sites for windfarm developments. The promotion of renewable energy is currently a priority given the environmental and economic drive to increase low-carbon energy production. Establishing windfarms on peatland in pursuit of greener energy, therefore, risks compromising and undermining the green-energy transition. Despite this, the extent of windfarm infrastructures on blanket bogs have not yet been reported at the European scale. This research reports the extent of windfarm infrastructures on recognised blanket bogs, with a geographical focus on Europe, where blanket bogs have been mapped systematically. Under the EU Habitats Directive (92/43/EEC), there are 36 European regions NUTS level 2 with recognised blanket bogs. Of these, 12 have windfarm developments, including 644 wind turbines, 253.4 km of vehicular access tracks and an affected area of 207.6 ha, mainly in Ireland and Scotland where the extent of blanket bogs is also higher. However, despite Spain having under 0.2% of Europe’s recognised blanket bogs area, this was the most affected country. In Scotland, a comparison of the recognised blanket bogs under the Habitats Directive (92/43/EEC) with blanket bogs recorded in national inventories indicates that the extent of windfarm developments was higher, with 1,063 wind turbines and 634.5 km of vehicular access tracks. Our results highlight the extent of windfarm developments on blanket bog habitat, both in areas where peatlands are broadly distributed across the landscape, and also in areas where this recognised habitat is particularly rare. There is a pressing need to assess the long-term impacts of windfarms on peatlands to ensure that efforts to meet energy targets result only in carbon sequestration, and do not jeopardise ecosystem services. Blanket bogs represent a particularly vulnerable habitat, the study of which should be prioritised updating national and international inventories to protect and restore this habitat.