bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient satisfaction with a clinically integrated sleep apnea care model vs. the current sleep care paradigm
Authors: Salinas Gregory D. , Cerenzia Wendy , Coleman Brandon , Thorndike Frances , Edington Samantha , Riney Heidi 
Published: January 2025

IntroductionSleep apnea can have severe negative health effects, including cardiovascular diseases, metabolic disorders, and decreased quality of life. Continuous positive airway pressure (CPAP) therapy is highly effective and the gold standard treatment for sleep apnea; however, traditionally fragmented sleep healthcare has resulted in low levels of treatment adoption and adherence. A recent white paper analysis of traditional health plan claims found that a comprehensive model significantly outperformed traditional health plans with higher rates of adoption (80 vs. 49%), adherence (62 vs. 25%), and persistence (53 vs. 11%) to CPAP therapy, which resulted in lower total healthcare costs. To understand the patient experience in these models of care, this study compared patient satisfaction between the traditional sleep care approach and a clinically integrated, comprehensive sleep care program.MethodsA survey was developed to understand differences in the patient experience with the two different care models with respect to: access to sleep care, including time from initial appointment to seeing a sleep specialist, referral and insurance process; ease of sleep testing process and receiving a diagnosis; adoption, quality of education, and training with CPAP; ongoing adherence support with CPAP, and quality of life. Data were compared using descriptive statistics and Chi-square analyses.ResultsA significantly higher proportion of patients in the comprehensive model were satisfied with all measured points in the patient's journey. Notably, twice as many patients in the comprehensive model were very satisfied with: ease of navigating the testing process, time between diagnosis and CPAP adoption, insurance navigation for CPAP approval, and availability and level of ongoing CPAP support. Comprehensive care patients experienced fewer work disruptions due to sleep apnea: only 7% missed work in the past 3 months, compared to 58% in the traditional model.DiscussionOverall, the study highlights the benefits of a comprehensive care model in improving patient satisfaction with their sleep apnea journey and overall quality of life for individuals with sleep apnea. Pairing this positive patient experience data with prior data from the same treatment model shows that removing obstacles within a patient's journey positively impacts satisfaction while simultaneously improving adherence rates and reducing total healthcare costs.
Effects of butyric acid glycerol ester supplementation on intestinal nutrient transporter and immune-related genes in broiler chickens challenged with Eimeria maxima
Authors: Kpodo Kouassi R. , Miska Katarzyna B. , Schreier Lori L. , Milliken Daniel J. , Proszkowiec-Weglarz Monika 
Published: January 2025

IntroductionCoccidiosis negatively affects intestinal health and digestive functions; however, whether butyric acid glycerol ester (BE) can mitigate these negative effects in broiler chickens is unknown. The study objective was to determine the effects of BE on nutrient transporter and intestinal immune genes in chickens infected with Eimeria maxima (EM).MethodsRoss male 708 chicks were fed diets supplemented with 0 (control, C) or 0.25% of BE. On day 21, half the chickens from each feeding group were infected with 0 or 103 EM sporulated oocysts creating four treatment groups (C, +EM, +BE, and BE + EM; n = 6/treatment group). Jejunal and ileal tissues were collected at days 7 and 10 post-infection (PI).ResultsEM infection reduced (P ≤ 0.02) nutrient transporter genes EAAT3, PEPT2, B°AT, GLUT2, GLUT5, and SGLT1 at days 7 PI in the jejunum and ileum and EAAT3, PEPT1, PEPT2, and B°AT at day 10 PI in the jejunum. The supplementation of BE increased CAT1 in the jejunum and PEPT1, GLUT2, and GLUT5 (P ≤ 0.04) in the ileum at day 10 PI. A BE x EM interaction was observed (P ≤ 0.02) where GLUT1 and GLUT2 were increased in the jejunum of +BE compared to C chickens at day 10 PI. Among the immune-related genes, EM reduced (P ≤ 0.0001) IgA in the jejunum but increased (P = 0.004) TGF-β4 in the jejunum and ileum at day 7 PI. The expression of pIgR was reduced, while TLR2 and TLR4 were increased in +EM compared to C chickens at day 7 PI. In addition, IgA was increased (P = 0.01) in the ileum of +BE compared to C chickens at day 10 PI.ConclusionThe results of the study confirmed that Eimeria maxima reduced nutrient transporters and immune-related genes in the jejunum and ileum of chickens. However, although BE increased the expression of some genes in non-challenged chickens, its supplementation did not prevent the reduction in the expression of selected genes caused by EM infection.
Which is more effective in thawing frozen rooster sperm: varying temperature or duration?
Authors: Nizam Mustafa Yiğit , Selçuk Murat , Esin Burcu 
Published: January 2025

IntroductionCryopreservation of poultry sperm is crucial for preserving genetic diversity and protecting endangered breeds. Rooster sperm is highly sensitive to cryopreservation due to its high polyunsaturated fatty acid content, making it prone to damage during freezing and thawing. This study evaluated the effects of thawing temperatures and storage conditions on sperm quality, including motility, morphology, and viability.MethodsFrozen rooster semen samples were thawed at 37°C for 30 seconds, 60°C for 5 seconds, or 72°C for 5 seconds and stored at 4°C for up to 48 hours. Sperm quality parameters, including motility, kinematic characteristics, abnormal morphology, and viability, were assessed at 0, 3, 6, 9, 12, 24, and 48 hours using a Computer-Assisted Semen Analyzer (CASA).ResultsPost-thaw motility varied significantly between thawing temperatures at 24 and 48 hours (p &lt; 0.05). Progressive and rapid progressive motility also differed significantly at 24 hours (p &lt; 0.05). Sperm viability showed statistical differences across thawing groups at 24 and 48 hours (p &lt; 0.05), while morphological abnormalities were significant at 12 and 48 hours (p &lt; 0.05). Across all groups, sperm quality parameters varied significantly at each time point (p &lt; 0.05).DiscussionThawing at 37°C and storing at 4°C for up to 24 hours optimizes sperm motility and viability, minimizing cryodamage and ensuring functional preservation. This approach is effective for short-term storage and crucial for sustaining genetic diversity and fertility in poultry breeding programs.
Laparoscopic Versus Robotic Ventral Hernia Repair With Intraperitoneal Mesh: A Systematic Review and Meta-Analysis Comparing the Perioperative Outcomes Randomised Controlled Trials
Authors: Singh Anurag , Toh Wei H. , Elzahed Nada , Khera Goldie , Baig Mirza K. , Mihailescu Andrei , Sajid Muhammad S. 
Published: January 2025

ObjectiveThe objective of this meta-analysis is to compare the perioperative surgical outcomes and cost-effectiveness of robotic ventral hernia repair (RVHR) versus laparoscopic ventral hernia repair (LVHR) with intraperitoneal mesh.MethodsRandomised control trials (RCTs) reporting perioperative outcomes and costs in patients undergoing RVHR versus LVHR were selected from medical electronic databases and meta-analysis was conducted in accordance with the guidelines of the Cochrane Collaboration using statistical software RevMan version 5.ResultsFour RCTs on 337 patients reporting perioperative outcomes and cost comparison were included. In the random effect model analysis, the duration of operation was shorter, and cost was lower in the LVHR group but with significant statistical heterogeneity [standardized mean difference (SMD) −48.07, 95%, CI (−78.06, −18.07), Z = 3.14, P = 0.002], [SMD 0.82, 95%, CI (−1.48, −0.16), Z = 2.45, P = 0.01]. However, the variables of hernia recurrence and surgical site complications were statistically similar in both groups without any statistical heterogeneity among the included studies [Risk Ratio (RR) 1.05, 95%, CI (0.22, 4.99), Z = 0.06, P = 0.95], [RR 0.85, 95%, CI (0.48, 1.50), Z = 0.55, P = 0.58].ConclusionThis systematic review demonstrates that RVHR does not offer any superiority among the compared perioperative variables (Duration of operation, hernia recurrence and surgical site complications) and it is not cost-effective when compared to LVHR. Due to the paucity of the RCTs and significant heterogeneity among the compared variables, a major multi-centre RCT is needed to validate these findings.
Staff and service user perspectives of a co-located homelessness centre in Scotland: a mixed-methods evaluation
Authors: Ng Lauren , Donaghy Eddie , Conway John , Mercer Stewart W 
Published: January 2025

BackgroundCo-location and integration of services within a psychologically-informed environment is recommended for people experiencing homeless but there are few examples of this in the UK. Such a centre opened in Scotland in November 2021.AimTo evaluate progress of the new centre.Design & settingMixed-methods pre-post-test design before (baseline) and two years after (follow-up).MethodBaseline and follow-up staff surveys measured knowledge of trauma-informed care, well-being, team climate, and job satisfaction. The follow-up staff survey also evaluated staff support and service improvements. In-depth staff interviews were conducted at baseline (n=25) and follow-up and analysed thematically. A service users survey was also conducted.ResultsThe staff survey showed significant improvements between baseline and follow-up in trauma-informed care, burnout, and team climate, together with improvements in support, service integration, and service user care. Service users reported high satisfaction with the new centre.Staff interviews identified a more psychologically-informed environment, better staff support, and improved opportunistic multidisciplinary working over the two years of the centre opening. However, a number of barriers were also identified relating to the building and the IT systems. Further work on the centre’s vision; short- and long-term integration plans; workload, and sustainability were felt to be needed.ConclusionCo-location of services for people experiencing homelessness in Scotland has led to improvements in staff burn-out and team climate, and service users’ satisfaction over the first two years of opening. However, barriers remain and full integration requires a clearer vision and ‘road map’, requiring collaborative leadership and sustainable funding.
Combination Oxylanthanum Carbonate and Tenapanor Lowers Urinary Phosphate Excretion in Rats
Authors: Medicherla Satya , Reddy Guru , Gupta Pramod , Chertow Glenn M. , Gupta Shalabh 
Published: January 2025

Background:
This study evaluated the combined effects of oxylanthanum carbonate (OLC), an investigational phosphate binder, and tenapanor, an approved sodium/hydrogen exchanger 3 (NHE3) inhibitor that reduces paracellular phosphate absorption, on urinary phosphate excretion in rats on a high phosphorus diet.

Methods:
Sixty-four male Sprague Dawley rats were randomized into eight groups: vehicle; tenapanor (0.15 mg/kg) only; OLC (0.75%, 1.5%, and 3%) only; and combination OLC (0.75%, 1.5%, and 3%) + tenapanor (0.15 mg/kg). Vehicle and tenapanor were dosed orally twice/day whereas OLC was incorporated into diets. We collected 24-hour urine samples to measure urinary phosphate excretion, a proxy for intestinal phosphate absorption efficiency. Primary analyses compared pooled results in the three OLC dose groups.

Results:
In the tenapanor 0.15 mg/kg group, mean urinary phosphate excretion from Days 9 to 11 was 8.5 mg/day (12.5%) lower compared to the vehicle group. In the OLC alone groups, mean urinary phosphate excretion (pooled across the 0.75, 1.5, and 3% OLC dose groups) was 12 mg/day (17.7%) lower compared to the vehicle group. Compared to vehicle, urinary phosphate excretion was 28.0 mg/day (41.3%) lower in the combination OLC + tenapanor groups (p=0.016). Bliss model of independence assessing the statistical significance between observed and predicted results indicated that combination OLC + tenapanor was synergistic (p=0.009 for 0.75% OLC + tenapanor and p=0.010 for 1.5% OLC + tenapanor).

Conclusions:
In summary, we demonstrated sizeable reductions in urinary phosphate excretion in response to OLC monotherapy and the most pronounced reductions in urinary phosphate excretion when using OLC in combination with tenapanor.
Estimating the Benefit of Transplant Over Dialysis in Candidates Over 55 Years
Authors: Stedman Margaret R. , Ahearn Patrick C. , Liu Christine K. , Chertow Glenn M. , Tan Jane C. 
Published: January 2025

Background:
‘Life Years from Transplant’ (LYFT) is a measure of the predicted difference between the expected lifespan with and without a kidney transplant. The metric was originally proposed in 1999; since then, demographics of the kidney transplant candidate population have materially changed.

Methods:
Using contemporary SRTR data, we propose more sophisticated methods for estimating LYFT with a focus on older kidney transplant candidates, a growing sector of the current candidate pool. We examine trends in predicted LYFT from 1995 to 2020.

Results:
We show that among older patients on the deceased donor waitlist, transplant remains a better option compared with dialysis (overall LYFT=5 years). LYFT trends have diminished modestly (by <1 life year) over time, in part related to efforts to enhance access to transplantation through intercurrent policy changes.

Conclusions:
Updated LYFT estimates remain informative clinical measures that can support patient-centered decision making. However less homogenous metrics with meaningful disaggregation are needed to inform institutional evaluation and policy change. Models should be repeatedly evaluated as demographics of the candidate pool evolve.
Разработка технологической модели гидропонной установки
Authors: Заболотских В.В. , Смахтина Л.А. , Евлеева М.Ю. 
Published: January 2025

На основе анализа существующих технологий культивирования растений и на основе экспериментальных исследований авторами разработана технологическая установка для выращивания овощей и зелени в лабораторных и тепличных условиях.
based on the analysis of existing technologies of plant cultivation and on the basis of experimental studies, the authors have developed a technological installation for growing vegetables and herbs in laboratory and greenhouse conditions.
Некоторые вопросы анализа конкурентоспособности продукции
Authors: Дабишева А.Ю. 
Published: January 2025

В статье рассматриваются основные факторы, влияющие на конкурентоспособность продукции, где главное внимание уделяется качеству. Приводятся основные сертификаты качества и их характеристики, а также методы повышения качества продукции. Качество продукции в современном мире является наиважнейшей проблемой, ведь от того, как решается данная проблема зависит экономическая и социальная ситуация в стране.
The article discusses the main factors affecting the competitiveness of products, where the main focus is on quality. The main quality certificates and their characteristics, as well as methods to improve product quality are given.The quality of products in the modern world is the most important problem, because the economic and social situation in the country depends on how this problem is solved.
Организация бухгалтерского учета товаров, анализ запасов торговой организации
Authors: Пешкова М.Е. 
Published: January 2025

все социально-экономические процессы, происходящие в нашем государстве на современном этапе, включая пандемию коронавируса, характеризуются все большим усложнением структуры торговли. Это прежде всего обусловлено расширением масштабов деятельности, ростом объема товарных масс, циркулирующих ее каналами, увеличением количества структурных элементов и разнообразием их связей между собой и поставщиками.
all the socio-economic processes taking place in our country at the present stage, including the coronavirus pandemic, are characterized by an ever-increasing complexity of the structure of trade. This is primarily due to the expansion of the scale of activity, the growth in the volume of commodity masses circulating through its channels, the increase in the number of structural elements and the diversity of their relations between themselves and suppliers.
Российский рубль от средневековья до наших дней
Authors: Микушова Н.С. 
Published: January 2025

Статья представляет собой ретроспективу развития рубля, рассказывая историю его взлетов и падений в результате различных реформ и кризисов. Автор рассматривает национальную валюту с точки зрения покупательной способности, а также эквивалентной стоимости в меде, серебре или золоте. В статье сделана попытка провести ретроспективу рубля за пять последних столетий и раскрыть историю долгого стремления страны к поставленной цели – созданию и модернизации своей денежной системы, наличию собственной стабильной валюты, а также показать покупательную способность рубля в течение последних 500 лет. Автор характеризует первую российскую валютную систему, сформированную в первой половине 16 века, описывает денежные реформы 17 века, внедрение денежных ассигнаций в 18 веке, масштабные денежные реформы С.Ю.Витте, и упадок российского рубля в послереволюционное время.
The article is a retrospective of the ruble's development, telling the story of its ups and downs as a result of various reforms and crises. The author considers the national currency in terms of purchasing power, as well as the equivalent value in honey, silver or gold. The article attempts to conduct a retrospective of the ruble over the past five centuries and reveal the history of the country's long pursuit of the goal of creating and modernizing its monetary system, having its own stable currency, as well as to show the purchasing power of the ruble over the past 500 years. The author describes the first Russian currency system formed in the first half of the 16th century, describes the monetary reforms of the 17th century, the introduction of monetary notes in the 18th century, the large-scale monetary reforms of S. Yu. Witte, and the decline of the Russian ruble in the post-revolutionary period.
Agile в управлении персоналом
Authors: Горобец К.В. 
Published: January 2025

На пороге Индустрии 4.0 традиционные принципы управления требуют переосмысления и трансформации. Вызовы, стоящие перед организациями нового типа, стимулируют последних быть одновременно инновационными, высокоэффективными, инициативными и прагматическими. Новые технологии и практики управления позволяют перезагрузить бизнес-процессы и настроить их под актуальные задачи. Внедрение технологии аgile предполагает активное вовлечение в работу всех членов команды, в том числе на этапах планирования и обсуждения промежуточных результатов. Итерационный подход к оценке результатов позволяет избежать многих рисков, связанных с актуальностью, социальной пользой, дефицитом финансирования. В статье представлена инновационная технология управления персоналом - agile, заимствованная из IT-сферы. Описаны разновидности agile и возможности их применения в управлении персоналом организации, а также алгоритм взаимодействия сотрудников согласно технологии agile. Проанализированы преимущества данной технологии, раскрыты перспективы, позволяющие достичь конкурентного преимущества за счет гибких методов.
Facing Industry 4.0, traditional management principles require rethinking and transformation. The challenges facing a new type of organization encourage the latter to be both innovative, highly effective, proactive and pragmatic. New technologies and management practices allow to reload business processes and configure them for current tasks. The implementation of agile technology involves active involvement of all team members, including at the stages of planning and discussion of interim results. An iterative approach to evaluating results avoids many of the risks associated with relevance, social benefits, and lack of funding. The article deals with an innovative technology of human resource management (agile), borrowed from the IT-sphere. The article describes the types of agile and the possibilities of their application in the HR management of the organization, as well as the algorithm of employee interaction according to the agile technology. The advantages of this technology are analyzed, and the prospects for achieving a competitive advantage through flexible methods are revealed.
Анализ структуры и доходности нематериальных активов Дагестанского государственного университета
Authors: Ахмедова Л.А. , Салатова Л.Г. 
Published: January 2025

В статье проведен анализ состава, структуры и динамики нематериальных активов ДГУ. Также изучена структура нематериальных активов по факультетам ДГУ. Проведен горизонтальный и вертикальный анализ нематериальных активов ДГУ за 2017 - 2018 гг. Кроме того проведен анализ структуры нематериальных активов ДГУ по срокам полезного использования и по правовой защищенности за 2018-2019 гг.
The article analyzes the composition, structure and dynamics of DSU intangible assets. The structure of intangible assets by faculties of DSU was also studied. A horizontal and vertical analysis of the DSU's intangible assets for 2017 - 2018 was performed. In addition the analysis of the structure of DSU's intangible assets by useful life and legal protection for 2018-2019 was conducted
Влияние covid-19 на государственно-частное партнёрство
Authors: Бугаенко Р.А. 
Published: January 2025

COVID-19 непосредственно является фактором современного кризиса, влияние которого распространяется на проекты государственно-частного партнёрства, что требует разработку мер по улучшению инфраструктуры проектов и предполагает поддержку бизнеса со стороны государства.
COVID-19 is directly a factor in the current crisis, the impact of which extends to public-private partnership projects, which requires the development of measures to improve the infrastructure of projects and involves government support for business.
Проблемы взаимодействия государства и частного бизнеса в рамках государственно-частного партнерства
Authors: Бугаенко Р.А. 
Published: January 2025

Несмотря на длительное время изучения сущности государственно-частного партнерства в настоящее время все равно сохраняется огромное количество проблемных моментов в процессе взаимодействия государства и частного бизнеса, которые необходимо устранять с целью повышения эффективности реализации совместных проектов.
Despite a long time studying the nature of public-private partnerships, at the present time, there still remains a huge number of problematic issues in the process of interaction between the state and private business, which must be addressed in order to increase the efficiency of joint projects.
Современные тенденции зеленых инвестиций в экономике Кыргызской республики
Authors: Сайпидинов И.М. , Осмоналиева А.А. 
Published: January 2025

В данной статье рассматриваются тенденции развития зеленых инвестиций в финансовой системе Кыргызстана за последние годы, состояние и перспективы его внедрения. Дано определение термину зеленые инвестиции. В процессе исследования авторы пришли к выводу, что вопросы по продвижению зеленого финансирования, зеленых инструментов в финансовом секторе находятся пока на начальном этапе. Но успешное внедрение «зеленых» инструментов и практика кредитования в финансовом секторе в дальнейшем будут основой для запуска Национальной системы зеленого финансирования в Кыргызской Республике.
This article discusses the development trends of green investments in the financial system of Kyrgyzstan in recent years, the state and prospects of its implementation. The term green investment is defined. In the process of the study, the authors came to the conclusion that the issues of promoting green financing and green instruments in the financial sector are still at the initial stage. But, the successful implementation of green tools and lending practices in the financial sector will continue to be the basis for launching the National Green Financing System in the Kyrgyz Republic.