bluuebunny/crossref_metadata_2025_split huggingface dataset:
How to publish in the Journal of Management Studies (JMS)
Authors: Potočnik Kristina 
Published: February 2023

It is our great privilege to welcome Kristina Potočnik to the Business School. Kristina is a leading Organizational Behaviour scholar and currently an associate editor at the Journal of Management Studies and International Journal of Selection and Assessment. She has kindly agreed to share her wisdom about: how to publish in elite Management journals, such as the Journal of Management Studies (JMS).We invite scholars of the Business School to join us for this workshop led by Kristina. This is a fantastic opportunity, particularly for emergent researchers and PhD students to get useful advice on how to prepare work for elite journals, how to make it beyond a desk reject, and how to eventually survive the review process.
Covid-19 and African E-Learning Systems: Structural and Institutional Strategies for Resilience and Antifragility
Authors: Akpan-Obong Patience 
Published: February 2023

ABSTRACT
This qualitative research examines how Nigeria, Seychelles, and South Africa applied technologies to mediate the impact of the COVID-19 lockdown on their education systems. The research demonstrates that sociocultural and institutional factors, and attitudes of stakeholders, rather than technological access, significantly determined the countries’ capacity to transition tertiary institutions online at the height of the pandemic. It expands the understanding of the role of institutions and policies in the adoption of education technologies. The research findings are expected to inform the articulation of relevant policies and system-wide strategies for resilience and antifragility in case of future societal disruptions.
The Background to ‘Believing Criticism’ in the Free Church of Scotland
Authors: Harman Allan 
Published: February 2023

This article argues that the introduction of ‘believing criticism’ in the Free Church of Scotland in the 19th century was not just a sudden development in the 1870s. Rather, the seeds of it go back much further, even to the Disruption itself. Some inappropriate decisions of the Free Church General Assembly, among other factors, paved the way for A. B. Davidson to commence lecturing on Pentateuchal criticism. His student, William Robert Smith, was not so discreet, and openly espoused views that departed from the teaching of the Westminster Confession of Faith. Dealing with him took several years, until he was relieved of his position in 1881, though not deposed from the ministry. By that time, ‘believing criticism’ was firmly entrenched in the Free Church.
AN EIF4G-RECRUITING APTAMER INCREASES THE FUNCTIONALITY OF IN VITRO TRANSCRIBED MRNA
Authors: Tusup Marina , Kundig Thomas , Pascolo Steve 
Published: February 2023

Background: As a versatile and safe vector, in vitro transcribed messenger RNA (ivt mRNA) is currently being intensively evaluated as an active pharmaceutical ingredient. Its therapeutic uses encompass vaccination, cell reprogramming, genome engineering, gene complementation and the expression of protein drugs (e.g., growth factors or antibodies).
Objectives: The therapeutic efficacy of ivt mRNA correlates with the efficacy of its translation. Untranslated regions (UTRs) from stable mRNA, such as globin mRNA, and optimized 5’ cap structures have been used to improve the functionality of ivt mRNA. However, the recruitment of the eukaryotic initiation factor 4E (eIF4E) protein to the 5’ end of transfected ivt mRNA remains a ratelimiting parameter for translation.
Method: We added aptamer sequences that bind the eiF4G protein to the 5’ UTR of ivt mRNA.
Results: One of the tested aptamer sequences produced a several fold increase in ivt mRNA expression (specifically, an increase of threefold to over tenfold depending on mRNA sequence and cell type).
Conclusion: This simple modification of the 5’ UTR of ivt mRNA may represent an efficacious and general method for improving the therapeutic index of all new mRNA-based therapeutic products.
Depression prevalence amongst patients with hepatitis C
Authors: Rasool Ghulam , Tareen Zarmina 
Published: February 2023

Background: Globally, hepatitis C is a serious health concern, and it is also becoming an alarming infection in our nation. The World Health Organization estimates that the hepatitis C virus infects 3% of people worldwide. Various study reported association of depression with hepatitis C virus infection. Objective: To assess the depression prevalence amongst patients with hepatitis c. Methodology: The current cross sectional study was carried out at Balochistan Institute of Psychiatry and Behavioral Sciences Quetta and Bolan Medical Complex Hospital Quetta from January 2019 to January 2020. Informed consent was taken in written from all the participants. Depressive symptomatolgy based on DSM 1V criteria was noted. A pre-designed proforma was then used to collect all the required information’s. The SPSS version 24.0 was used to input and analyze the data. Results: In the current study, a total of 120 hepatitis C patients were enrolled. There were 66 (55%) males and 54 (45%) females. Te mean age (SD) of the patients in our study was 42 (11.23) years. The overall frequency of depression amongst patients with HCV was 102 (85%).
Pengaruh Disiplin Kerja dan Kepuasan Kerja Terhadap Produktivitas Kerja Pegawai di Satuan Pelayanan Terminal Tipe A Batu Kuning – OKU Sumsel
Authors: Hilmi Wiranawata  , Riki Adriant  , Fitri Anita  
Published: February 2023

Penelitian ini membahas Pengaruh Disiplin Kerja dan Kepuasan Kerja terhadap Produktivitas Kerja Pegawai di Satuan Pelayanan Terminal Tipe A Batu Kuning Kab. OKU. Hasilnya menunjukkan secara parsial thitung variabel Disiplin Kerja (X1) sebesar 6,713 dengan ttabel = 2,04841 atau 6,713> 2,04841 artinya Disiplin Kerja berpengaruh signifikan terhadap Produktivitas Kerja. Variabel Kepuasan Kerja (X2)thitung= 2,304, dengan ttabel = 2,04841. Berdasarkan kriteria keputusan ternyata nilai thitung>ttabel atau 2,304> 2,04841, artinya Kepuasan Kerja berpengaruh signifikan terhadap Produktivitas Kerja Pegawai. Fhitung sebesar 100,481 dan F tabel 3,34. Jadi F hitung >F tabel atau 100,481> 3,34, artinya seluruh variabel X yaitu Disiplin Kerja (X1) dan Kepuasan Kerja (X2) secara bersama-sama berpengaruh terhadap Produktivitas Kerja Pegawai di Satuan Pelayanan Terminal Tipe A Batu Kuning Kab.OKU Karyawan.
OPTIMASI SUHU INKUBASI TERHADAP MUTU KEFIR EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa L)
Authors: Nurfadilah Sri , Nurfadilah Sri 
Published: February 2023

Penelitian ini bertujuan untuk mengetahui adakah pengaruh pemberian variasi suhu dan ekstrak bunga rosella (Hibiscus sabdariffa L) terhadap kefir, mengetahui pada suhu berapakah kefir ekstrak bunga rosella (Hibiscus sabdariffa L) memiliki mutu yang baik. Penelitian ini merupakan penelitian eksperimental laboratorium meliputi pembuatan formulasi kefir dengan pengujian mutu dan keamanan melalui uji pH, total asam, bakteri asam laktat (BAL) uji penerimaan produk secara hedonik (rasa, warna, aroma dan tekstur) dan cemaran mikroba (Escherichia coli).Data yang diperoleh dari hasil pengujian pH, uji asam, uji BAL dianalisis secara deskriptif. Data yang diperoleh pada uji organoleptik dianalisis dengan uji non parametrik (uji Kruskal Wallis). Dari hasil analisis data diperoleh formula terbaik kefir.setelah itu dilakukan pengujian cemaran mikroba Escherichia coli yang dianalisis secara deskriptif.Hasil penelitian menunjukkan bahwa terdapat pengaruh pemberian variasi suhu dan ekstrak bunga Rosella terhadap uji pH, total asam, uji BAL, uji organoleptik. kefir pada fermentasi 250C paling baik dari segi pH 3,12, total asam 1,45%, BAL 4,75 x 108, organoleptik warna 6,55, aroma 4,4, rasa 4,15 dan tekstur 6,1 serta uji Escherichia coli tidak ditemukan pada kefir.
Evaluation of Physical Characteristics of Soils Derived from Basement Complex Rocks of the Jos Plateau
Authors: Owonubi Ayodele 
Published: February 2023

The physical characteristics of soils to a large extent influences soil productivity. The objective of this study therefore is to evaluate the physical characteristics of soils derived from basement complex rocks of the Jos Plateau. According to the methodology outlined in the Soil Survey manual, the stratification of the study region into three geologic units—granite gneiss, biotite granite, and migmatite—was the first step in the soil research process. Additionally, soil samples were collected from genetic strata and soil profile pits were dug in each of these geologic units. Following standard procedure soils were analyzed for color, particles size distribution, structure, and bulk density. Results indicated that physical soil characteristics over the geologic units studied were in most cases similar. However significant differences were observed in particle size distribution in the A-horizons. Clay content in the A horizon of these soils generally ranged from a minimum of 8% to a maximum of 28%. Clay content in the A-horizons of the magmatic soils were significantly higher (P<0.05) than soils over granite gneiss but statistically similar (P>0.05) to those of biotite granite. Particle size distribution data indicate that the soils have undergone intensive weathering. Soil structures were on the average moderately developed in the soils studied with angular and sub-angular blocky structures. Although there was evidence of soil compaction to suggest plant root development could be affected or inhibited in these soils.
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Relationships Between pH Buffer Capacity and Selected Soil Properties of an Agrarian area in Samaru, Nigeria
Authors: Owonubi Ayodele , Kenneth Chiwendu 
Published: February 2023

The objectives of this research were to investigate the nature of pH buffer capacity and evaluate its association selected soil characteristics the study area. Soil samples from ten profile pits from within the study area were collected from genetic horizons. Soil samples were tested in the laboratory for electrical conductivity and pH buffer capacity using standard procedures. Soil data were analyzed using descriptive statistics. One-way analysis of variance and correlation analysis were applied to determine effects and relationships of selected soil properties with soil pH buffer capacity. The selected soil properties included particle size distribution, electrical conductivity, organic matter, cation exchange capacity and soil pH. Analysis of variance indicated that there were no significant effect of soil depth or drainage condition on distribution of pH buffer capacity in the study area. Correlation analysis indicated a non-significant weak relationship between pH buffer capacity and selected soil properties of the study area. This suggest that multiple interrelated factors could be responsible for the distribution of pH buffer capacity in the study area.
Ocular Syphilis: A Case of Progressive Bilateral Panuveitis
Authors: Hunter Amanda , Glickman Amanda , Greenberg Paul B. , Doyle Rebecca , Janigian Robert 
Published: February 2023

Significance This report outlines a case of progressive bilateral granulomatous panuveitis secondary to syphilis. Purpose To describe the management of a case of progressive uveitis secondary to syphilis. Case Report A 60-year-old male with a three-month history of redness and floaters presented with bilateral chronic granulomatous anterior uveitis. He was started on difluprednate emulsion four times a day in each eye. The patient’s clinical course improved until he tapered off the drops, upon which he presented with a progressive bilateral panuveitis. A diagnostic work-up in collaboration with the hospital infectious disease department led to a diagnosis of neurosyphilis. The patient was treated with intravenous penicillin with eventual resolution of his ocular inflammation. Conclusions This case report underscores the importance of obtaining a detailed case history and taking a multi-disciplinary approach to patients with progressive uveitis. CE Notification This article is available as a COPE accredited CE course. You may take this course for 1-hour credit. Read the article and take the qualifying test to earn your credit. Click here to Enroll (https://www.crojournal.com/ocular-syphilis-a-case-of-progressive-bilateral-panuveitis) Please check COPE course expiry date prior to enrollment. The COPE course test must be taken before the course expiry date.
The Efficacy and Safety of Oral Ferrous Gluconate in Premenopausal Women with Severe Iron Deficiency Anaemia
Authors: Tazeen Fatima Munim  , Shaista Rashid  
Published: February 2023

Objective: To evaluate the efficacy and safety of ferrous gluconate, given orally thrice daily for three months, to pre-menopausal women with severe iron deficiency anaemia.
Method: A phase IV non randomized single arm open label drug trial was conducted at Gynaecology and Obstetrics Unit II in Abbasi Shaheed Hospital from Feb 2013 to March 2014, which is a 950 bedded public sector tertiary care hospital.
Total fifty premenopausal women with documented severe iron deficiency anaemia, haemoglobin (Hb) between 6-8 g/dl were enrolled after taking written informed consent. Clinical evaluation and lab in- vestigation for serum ferritin and haemoglobin levels were conducted at baseline and after comple- tion of treatment. A standardized proforma for data collection was developed. Ferrous gluconate soft gelatin capsules were given as one capsule during or after the meal 3 times daily, for three months. All patients were evaluated four times during study first at the time of enrolment and after 30, 60, and 90 days for clinical efficacy and safety assessment.
Results: In our study all fifty premenopausal women completed iron treatment. Analysis of therapeutic efficacy parameters i.e. haemoglobin, and serum ferritin levels showed improvement that was sta- tistically significant. By the end of treatment with oral ferrous gluconate, significant improvement in Hb levels was observed (7.574 ± 0.559 g/dl vs 11.020 ± 0.718, p<0.0001). Significant changes were noted in serum ferritin level (10.058 ± 5.059 ng/ml vs 27.136 ± 13.803, p<0.0001) after 3 months therapy. Ferrous gluconate proved to be safe in women with severe iron deficiency anaemia. The treated women did not exhibit any major side effect, only one serious side effect was reported (erythema nodosum). Mild self-limiting side effects including black discolouration of stool in 54% cases, nausea in 6%, constipation in 2% and diarrhoea in 2% was observed.
Conclusion: Oral ferrous gluconate treatment for severe iron deficiency anaemia is well tolerated and highly effective in premenopausal women.
Patient Satisfaction from Dental Services Provided by Multan Medical & Dental College
Authors: Ejaz Hussain Sahu  , Muhammad Umer Abdullah  , Rai Tariq Masood  
Published: February 2023

Objective: The aim of this study was to assess the level and factors influencing the level of patient satisfaction from dental services provided by Multan Dental Hospital.
Methods: Study was carried out at Multan Dental hospital from 1st June to 30th July 2015. Total 256 patients over 18 years of age, participated in this cross-sectional study. Convenient sampling tech- nique was used to select the patients. The Hogan Patient Satisfaction Questionnaire was customised, personalised and used for this dental patient satisfaction study, and response through a Likert scale including answer categories very satisfied, satisfied, neutral, not satisfied, not at all satisfied and do not know, was completed by the participants. SPSS software version 17 was used for analysis. The relationship between level of patient satisfaction and the demographic variables was determined, Chi-square test was performed to establish the level of patient satisfaction and if af- fected by the demographic variables.
Results: Total 29.3% patients said that they were very satisfied with the services. About 43.4% partici- pants were satisfied with the services. Not satisfied with service were 8.6%. A very low proportion (5.9%) of patients were completely dissatisfied with the services. There were 42% males and 30% fe- males who were satisfied with the services. About 49% of patients having an education between 6-14 years were satisfied from the hospital services while only 9% of patients having higher education level were satisfied. The major proportion of the patients showed satisfaction from the services of- fered at the hospital.
Conclusion: Majority of the patients were satisfied with the services regarding hospital care, dental staff provided by Multan Medical and Dental College.
Glycaemic Control and Complications of Type II Diabetes Mellitus - At Two Public Sector Diabetic Clinics
Authors: Kulsoom Jawed  , Nighat Nisar  , Mehwish Hussain  
Published: February 2023

Objective: To determine the frequency of complications including retinopathy, nephropathy, cardiovas- cular diseases and neuropathy and to determine the relationship between poor glycaemic control and complications among diabetic patients visiting outpatient clinics of tertiary care hospitals of Karachi.
Methods: A cross-sectional descriptive study was conducted for a period of six months from April 2015 to September 2015 at the diabetic clinics of Civil Hospital and National Institute of Diabetes and Endocrinology after taking the ethical approval from the Dow University of Health Sciences (DUHS). Type II diabetic patients (n=400) were included through purposive sampling technique after taking written consent. Pregnant/lactating women and terminally ill diabetic patients were excluded. Data was collected through a pre-designed questionnaire. Data was entered and analyzed by SPSS
v.21.00. Frequencies and Percentages were calculated. Regression analysis was performed to deter- mine the relationship between glycaemic control and complications of diabetes.
Results: Out of 400 diabetic patients, 323 (90%) participants were above 40 years of age, 278
(69.5%) were females and 122 (30.5%) were males. About 28.8% had cardiovascular complications, 19.2% had renal complications, 65.3% had visual problems and 58% experienced loss of sensation. Approximately 59.5% patients had poor glycaemic control while 39.5% had good glycaemic control. Patients with poor glycaemic control (HbA1c >8.0) were at a higher risk of developing hypertension and numbness of hands and feet.
Conclusion: This study concluded high frequency of complications among Type II diabetes mellitus patients. Proportion of poor glycaemic control was found high. Diabetic complications were associ- ated with poor glycaemic control.
Awareness Regarding Breast Cancer a Global Health Problem - A Study amongst Adult Women in Karachi
Authors: Yasmin Mumtaz  , Nusrat Iqbal  
Published: February 2023

Objective: To determine the level of knowledge regarding breast cancer amongst women and their practice of breast self-examination.
Methods: A Knowledge, Attitude and Practice (KAP) study was conducted in the community of Gulshan Town, Karachi, during July 2013 to June 2014 through non-probability convenient sampling technique after taking written consent. The sample size of 560 was calculated by using World Health Organization (WHO) calculator. All women aged 20-40 years were included except those who had breast cancer and any type of swelling in the breast. Data was collected through semi-structured questionnaire. Data was entered and analysed on SPSS 16. For descriptive statistic mean ± SD and frequencies were calculated.
Results: A total of 559 women participated. Mean age of women was 30 ± 1.5 years. About 84% fe- males were married, 37% attained education in universities and 71% were housewives. Around 34% women thought that frequency of breast cancer was present in one out of every 9 women, while, 60% said breast cancer is a genetic disease. Those who said breast cancer is not accompanied by painful swelling were 61%. While 79% women said a swelling in the breast is not always breast cancer and 64% said that mastectomy is the only treatment of breast cancer. The women who said that use of contraceptives was closely associated with breast cancer were 69% women, 83% thought breast feeding decreases the risk of breast cancer while 45% women did not know what precautions to take against breast cancer. Only 40% women said consumption of fruits and vegetables decreases the in- cidence of breast cancer. Regarding awareness of the breast self-examination, 56.9% responded negatively.
Conclusion: The study concluded that overall knowledge regarding breast cancer was low. The practice of breast self-examination in this cohort of subjects was only 40%. We recommend public awareness regarding the risk and screening modalities for breast cancer, and breast self-examination be emphasised using mass media.
Bullous Impetigo Case Series: An Updated Review
Authors: Mariam  Hasan  Rizvi  , Sina Aziz  
Published: February 2023

Impetigo also known as pyoderma is a common paediatric skin infection presenting to clinics and hospitals in summer season. The illness is acquired from close skin contact with the victim and is highly contagious. The lesions are fluid filled vesicles that leave crust after rupture and usually heal without treatment. The infection is classified as bullous and non-bullous impetigo, the latter one having the least occurrence and is most commonly associated with complications, therefore prompt treatment is necessary.
The case series holds a brief literature review of bullous impetigo, its clinical course, treatment op- tions and complications. The author reports two cases presenting with bullous impetigo in the month of June. A five-year old boy and fifteen months old girl; both presenting with similar rashes involving limbs, trunk and neck with slight differences in the clinical symptoms. Both were treated with fluids, oral and topical antibiotics. The climatic conditions of Karachi favours the incidence of impetigo. Also, poor sanitation and overcrowded areas have further more increased the incidence of the disease. Families are unaware of these types of skin infections and hence do not isolate the victim which, in case of highly contagious illnesses like impetigo, is of great importance. Furthermore, not getting prompt treatment is another factor that cannot be ignored and results in complications in case of bullous impetigo. The most important conclusions which can be drawn from our case series are the lack of paediatric centres that treat dermatological conditions promptly and effectively. Lack of proper guidance convinces families to switch to self-medication and sometimes neglect. The role of a paediatrician is vital when creating understanding with the patient's attendant by explaining them the clinical features and course of treatment of bullous impetigo to avoid self-medication while dealing with skin diseases in children.