bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Umur Ibu Dan Jarak Kehamilan Dengan Kejadian Preeklampsia Pada Ibu Bersalin
Authors: Eka Juniarty  , Pera Mandasari  
Published: April 2023

Penyebab pasti preeklampsia masih belum diketahui secara pasti. Namun ada beberapa faktor resiko yang dapat mendukung timbulnya preeklampsia antara lain faktor umur, jarak kehamilan dan kehamilan ganda, riwayat preeklampsia sebelumnya, riwayat dalam keluarga dan penyakit yang menyertai kehamilan seperti penyakit ginjal dan diabetes melitus. Tujuan penelitian adalah untuk mengetahui hubungan umur ibu dan jarak kehamilan dengan kejadian preeklampsia pada ibu bersalin di Rumah Sakit Umum Daerah Kota Prabumulih Tahun 2021. Desain penelitian menggunakan Cross Sectional. Populasi penelitian ini adalah keseluruhan ibu yang melahirkan diRumah Sakit Umum Daerah Kota Prabumulih tahun 2021. Pengambilan sampel pada penelitian ini menggunakan tehnik sampel random sampling yaitu sebanyak 326 responden. Instrumen penelitian berupa checklist. Hasil penelitian didapatkan ada hubungan antara umur ibu (p value = 0,000) dan jarak kehamilan (p value = 0,000) dengan kejadian preeklampsia di RSUD Kota Prabumulih tahun 2019. Simpulan ada hubungan yang bermakna antara umur dengan ada hubungan bermakna antara jarak kehamilan dengan preeclampsia
Tratamiento ultraconservador con Papacarie en niños de 5 a 7 años que acudieron a la Clínica Odontológica Universidad Privada del Valle Cochabamba
Authors: Espinoza Paredes Melvy 
Published: April 2023

El tratamiento de lesiones cariosas en niños sigue los mismos principios que en el adulto, con las diferencias de menor estructura dental y ante todo la cooperación del paciente pediátrico en el tratamiento, lo cual es posible mejorar mediante el manejo adecuado de la conducta del niño.
Se realizó un trabajo de investigación con el objetivo de determinar la eficacia del gel Papacarie@ para la remoción de caries en pacientes entre 5 a 7 años, atendidos en la Clínica Odontológica Universidad Privada del Valle Cochabamba Gestión 2010, que presentaban caries de segundo grado.
Esta investigación fue de tipo prospectivo, longitudinal y analítico; el universo estuvo conformado por 50 piezas temporarias posteriores con caries de segundo grado que no presentaron sintomatología dolorosa, a las cuales, luego de aplicarles el Papacarie@ por 40 segundos, se procedió a retirar el tejido cariado con cucharetas de dentina para posteriormente obturarlas con un cemento ionómero de vidrio de obturación. Este producto no afecta a la estructura dental remanente, lo que facilitó la colaboración de pacientes poco cooperadores, aunque el tiempo de trabajo se incrementó.
Los principales resultados fueron: la pieza con mayor porcentaje de caries fue el segundo molar superior temporario izquierdo con 16 %, siendo más afectados los pacientes de 5 años; según género, las niñas presentaron mayor frecuencia de caries en dientes del maxilar inferior y para maxilar superior los niños fueron más afectados; comparativamente, más niñas que niños requirieron una segunda y hasta tercera aplicación del producto para la remoción total de la caries, que fue lograda en general en un 100 % (con una aplicación en 70 % de los casos, con dos aplicaciones el 20 % y con tres el 10 % de los casos); no se evidenció ningún cambio radiográfico en los controles realizados al mes y a los dos meses de aplicado el producto.
Con respecto al dolor durante la ejecución de la técnica en la investigación realizada en la Clínica, ningún paciente presentó este síntoma, al igual que los pacientes del estudio de Satie y cols; de similar forma ningún paciente presentó alteraciones clínicas o radiográficas posteriores al tratamiento recibido, tanto en el estudio de Satie y cols., como en el realizado en la Clínica.
Physicochemical Properties of Single Cell Oil Extracted from Oleaginous Yeasts
Authors: Elmahe Rania. A. , Elkhalil Elhadi. A. I. , Yousif Nabila. E. 
Published: April 2023

The study aimed at extracting single cell oil (SCO) from some oleaginous yeasts living on wheat straw and sugarcane molasses media and to determine physicochemical properties of the produced oil for further assessment as edible oil. Thirty samples of yeasts were isolated according to the different methods based on the source of isolates. The effectiveness of oleaginous yeast to produce the single cell oil was studied, when the yeast was grown on two types of wheat straw media (detoxified liquid hydrolysate (DLH) and non-detoxified liquid hydrolysate (NDLH)), and molasse media. Single cell oil was extracted by hexane. Saccharomyces cerevisiae and Pichia guilliermondii were used to produce SCO. SCO produced from oleaginous yeasts in sugarcane molasses media was significantly (P≤0.05) higher than that produced in wheat straw media. DLH of wheat straw gave higher productivity of oil than NDLH wheat straw. Generally, S. cerevisiae gave higher oil productivity (84 %), compared to P. guilliermondii (52 %).The results indicated that most of the physicochemical properties of extracted oil were found to be within the recommended limit of the common edible oil reported, except for the iron content; it ranged from 21 to 24 mg/kg, which was 4-5 times more than the permissible level of that of the Codex Alimentarius Commission. In addition, single cell oil produced by molasses contained omega-3 fatty acids such as eicosapentaenoic and docosahexaenoic which are not found in vegetable oil. Also the unsaturated fatty acids of SCO produced in wheat straw media were higher than that produced in molasses media. The fatty acid profile of SCO produced in molasses media was different from that of vegetable oils. The good physicochemical characteristics and fatty acids profile of SCO from wheat straw make it safe and a promising potential raw material for production of edible oil. The result of this study suggests the isolation of oleaginous yeast in order to be used in the edible oil production
A note on Microbiological and Biochemical Evaluation of ʻOmtiganiaʼ, a Sudanese Fermented Food Based on Peanut Seed Cake
Authors: Ali Siham Eltayeb Mohamed , Elkhalil Elhadi Ali Ibrahim 
Published: April 2023

The objectives of this study aimed to evaluate the microbiological and biochemical changes during the fermentation of peanut (Arachis hypogaea) seed cake. The microflora during fermentation was dominated by a homo fermentative lactic acid bacterium (Streptococcus sp and lactobacillus sp) initially, the yeasts and mould and acetic acid bacteria were also present. The accumulation of acids led to the decline of the pH of the mixture from 5.7 to 3.6 on the seventh day of fermentation. Dried ʻOmtiganiaʼ possessed a crude protein content of 67 %. The microbiological analysis showed that the microbial population is mainly bacteria.
Tratamientos de primera línea para pacientes estadio IV con adenocarcinoma pulmonar de mutación EGFR
Authors: Pohl V Emilio , Pozo U Sebastián , Poblete C Javiera , Muñoz M Agustín , Segura B Francis 
Published: April 2023

Lung cancer is one of the leading causes of death in the world. Current treatments act directly on the signal transduction pathways in cancer cells, mainly. One of the main pathways is associated with the Epidermal Growth Factor (EGFR), whose mutations leads to uncontrolled cell proliferation and a higher rate of cell invasion. Activating mutations in the EGFR gene, which includes deletions in exon 19 and the L858R mutation in exon 21, were detected in most patients with non-small cell lung cancer (NSCLC). Studies of EGFR tyrosine kinase inhibitors (EGFR-TKIs) such as Gefitinib, Erlotinib and Afatinib, compared with platinum-based treatments, showed that EGFR-TKIs produce increased disease-free survival, although only in patients whose cancers harbor activating mutations in the EGFR gene. Clinical trials also demonstrated that EGFR-TKIs are effective as first-line therapies in stage IV pulmonary adenocarcinoma. Here,
the main aspects of the activation of the EGFR pathway in NSCLC will be reviewed, highlighting the importance for health professionals of correctly identifying activating mutations in the EGFR gene and acting quickly at the molecular level based on aforementioned treatments.
Características de los coronavirus, origen del SARS-CoV-2, características estructurales, proteínas y factores de virulencia, variantes genéticas
Authors: Isler I. Dayanne , Palma P. Valeria 
Published: April 2023

Coronaviruses (CoVs) were identified in 1937, they were considered innocuous viruses until the
appearance of three highly pathogenic variants, SARS-CoV, MERS-CoV and SARS-CoV-2 causing
the current pandemic of Covid-19, so far it is known that its origin is zoonotic, the main reservoir
could be bats considering the high homology of CoVs that inhabit this species. Its transmissibility
is much higher than that of previous CoVs, possibly in the process of natural selection; it has
acquired some or all the mutations necessary for a much more efficient transmission in our
species. This condition is specifically attributed to unique characteristics of the SARS-CoV-2
Spike protein that allow it greater affinity and therefore greater infectivity by binding to the
angiotensin receptor 2 (ACE-2) present in the host cells. Since the Covid-19 outbreak began at
the end of 2019, more than 1,500 mutations have been detected throughout the SARS-CoV-2
genome, however the most significant are those that occur near or in the receptor binding
domain (RBD) that could provide variations between 4x to 100x greater infectivity, such is the
case of the new variants identified in the United Kingdom, South Africa, Brazil and Japan that
force us to take extreme preventive measures and continue research to elucidate strategies to
combat the current crisis.
Patogenia de la infección por SARS-CoV-2
Authors: Faúndes G Nicolás , Genskowsky V Karen , Tordecilla F Rocío 
Published: April 2023

Covid-19 is an infectious disease whose etiological agent called SARS-CoV-2. It has a high
contagion rate, high morbidity and mortality, and potential multi-organ compromise. Its main
route of infection is by droplets, however, the infection can be acquired by other routes such
as aerosols, fecal-oral and contact with fomites. Although the immune response is essential
for defense against any infection, in severe Covid-19 infection, a dysregulation of the immune
system occurs, which leads to marked increases of cytokines and the consequent systemic
inflammatory state. Inflammation, infection, and viral shedding can compromise the lungs,
blood vessels, brain, gastrointestinal (GI) tract, kidneys, heart, and liver, ultimately leading to
multiple organ dysfunction and failure.
Maxillofacial prosthesis’s effect on oral hygiene and oral health related quality of life of patients in a population of Pakistan
Authors: Riaz Hira , Ilyas Hira , Meer Ali Asmar , Gulzar Muhammad , Tahir Izah , Ahmed Asrar 
Published: April 2023

Background and Aim: Dental malformations caused by surgical excision of oral cancerous tissues cause physical, functional and aesthetic problems. Congenital disorders or acquired factors are regarded as the major causes for maxillofacial defects. The purpose of the current investigation was to determine the effect of maxillofacial prosthesis on oral hygiene and oral health related life quality of life of patients in a population of Pakistan. Materials and Methods: This prospective study was conducted on 28 maxillofacial defects’ bearing patients investigated in the Department of Dentistry at a Tertiary Care Hospital in Lahore, Pakistan from January 2021 to December 2022. Hearing as well as visually impaired and edentulous patients were excluded from the study. Oral Health Impact Profile (OHIP) was used for the assessment of Oral Health related Quality of Life (OHR QoL). The OHR-QoL was assessed by a self-administered questionnaire. “Functional limitation (9 items)”, “Physical pain (9 items)”, “Psychological discomfort (5 items)”, “Physical disability (9 items)”, “Psychological disability (6 items)”, “Social disability (5 items)”, and “Handicap (6 items)” were 7 subscales of OHR-QoL recorded in each questionnaire and a greater OHR-QoL impairment was an indicative of a higher overall OHIP score.
Manajemen Pelayanan dalam Peningkatan Mutu Pendidikan Inklusi Sekolah di Tulungagung
Authors: Januariani  , Prim Masrokan  , Imam Fuadi  
Published: April 2023

This study aims to determine the implementation of service management in improving the quality of inclusive education. This research was conducted at SD Muhammadiyah 1 Tulungagung, SDI Al-Azhaar Tulungagung, and MI Modern SAKTI Tulungagung. This research uses a qualitative approach of the type of case study. The results showed that the management of inclusion education services was carried out by providing facilities and infrastructure in accordance with the needs of Students with Special Needs (PDBK), competent educators, modifying the curriculum and assessment system for PDBK, and creating a pleasant learning atmosphere. The implementation of service management in the three educational institutions has their own characteristics in accordance with the vision and mission of the school. Although there are different objectives, basically the objectives of education still refer to the quality standards specified in the applicable laws and regulations.
Standar Kompetensi Mentoring Dalam Kaderisasi Pelayan Kristus Konteks Remaja Generasi Z
Authors: Yuliati Yuliati , Susilowati Yuni 
Published: April 2023

Abstract :Generation gap obstruct generation Z teenager in the training process to become a servant of Christ servant. Mentoring proposed to overcome generation gap problem in generation Z. However, the existing mentoring system does not yet have biblical competency standards that suitable with the context of generation Z teenager. This research aims to make biblical competency standards in mentoring process in order to prepare generation Z teenager be a servant of Christ. The researcher hopes that generation Z can be well prepared so that Christian ministri can last forever. This resereach use Grounded Theory metode. This research use literature study and survey to collect data. The survey was carried out using a google form questionnaire that was distributed to 102 teenagers aged 12-21 years that scattered in various cities on the island of Java. This study resulted in 11 competency standards in mentoring. Generation Z teenager must meet these 11 competency standards to graduate from mentoring and become a servant of Christ. Keyword : generation Z teenager, mentoring, competency standards Abstrak :Jurang generasi menghambat proses kaderisasi remaja generasi Z. Mentoring diusulkan untuk mengatasi jurang generasi pada generasi Z. Namun sistem metoring yang ada belum memiliki standar kompetensi alkitabiah yang sesuai dengan konteks remaja generasi Z. Tujuan penelitian ini adalah membuat standar kompetensi alkitabiah pada proses mentoring dalam rangka kaderisasi pelayan Kristus konteks remaja generasi Z. Harapan peneliti yaitu generasi Z dapat dipersiapkan dan dikader dengan baik sehingga pelayan Kristen dapat terus berlangsung. Penelitian ini mengunakan metode Grounded Theory. Penelitian ini mengumpulkan data dengan metode studi pustaka tentang tema yang terkait. Penelitian ini juga mengumpulkan data melalui survei singkat. Survei dilakukan dengan menggunakan angket google formulir yang disebarkan kepada 102 remaja berusia 12-21 tahun yang tersebar diberbagai kota dipulau Jawa. Penelitian ini menghasilkan 11 standar kompetensi dalam mentoring. Remaja generasi Z harus memenuhi 11 standar kompetensi ini untuk lulus dari mentoring dan menjadi seorang pelayan Kristus. Kata kunci : Remaja Generasi Z, Mentoring, Standar Kompetensi
ATUAÇÃO DE UM BANCO DE DESENVOLVIMENTO SOBRE A ÓTICA DA INCERTEZA E DO ESPAÇO NA DISPONIBILIDADE DO CRÉDITO
Authors: De Queirós Juliana Clyde Fernandes Ferreira 
Published: April 2023

A atuação da firma bancária na disponibilização do crédito pode trazer consigo uma responsabilidade social ao gerar renda e promover o desenvolvimento econômico (Dutra & au, 2015). Tendo por base os conceitos de espaço e incerteza, bem com a atuação dos Bancos Públicos em cenários anticíclicos, o presente trabalho buscará analisar em que medida o Banco do Nordeste- BNB atuou em comparação com os demais Bancos de forma a promover reações anticíclicas de disponibilidade do crédito levando-se em consideração as premissas de espaço e incerteza. Através da análise realizada nos municípios estudados, pôde-se concluir que o BNB, apesar de disponibilizar volume de crédito relativamente inferior aos demais bancos, cumpriu seu papel de fomentador do desenvolvimento local ao financiar mini produtores e pequenas empresas locais, público que dificilmente teria possibilidade de acesso ao crédito.
PERILAKU KADER POSYANDU DALAM PEMBERIAN MAKAN PADA BAYI DAN ANAK
Authors: Efrizal Wiwin , Utami Rezie , Sulaiha Sulaiha , Mangunsong Lystramika 
Published: April 2023

Pengetahuan kader terkait Pemberian Makanan bagi Bayi dan Anak (PMBA) menjadi salah satu factor mempengaruhi upaya penanggulangan masalah gizi dan kesehatan. Perilaku kader pada keluarga sendiri akan meningkatkan pemahaman melakukan konseling PMBA. Penelitian ini bertujuan memberikan gambaran perilaku kader posyandu dalam PMBA. Desain menggunakan potong lintang dengan sasaran kader posyandu aktif di wilayah Puskesmas Pangkalan Baru dan Benteng Kabupaten Bangka Tengah. Pengumpulan data dilakukan September hingga Oktober 2021 menggunakan google form dan terdapat 85 orang kader yang bersedia. Sebagian besar kader sebagai ibu rumah tangga dan sebanyak 68,2% pernah mengikuti pelatihan konseling PMBA. Kader yang mempunyai Balita sebanyak 61,2% dan sebanyak 87,5% memberikan ASI eksklusif. ASI tidak cukup menjadi salah satu alasan 12,9% responden untuk tidak melanjutkan setelah usia enam bulan. Kader yang memberikan MP-ASI saat Balita berusia enam bulan sebanyak 94,1%. Sumber hewani digunakan dalam MP-ASI oleh 27,1% responden dan sayuran oleh 41,2% responden serta buah-buahan diberikan oleh 27,1% responden. Makanan bentuk kental diberikan oleh 72,7% responden dan sebanyak 69,4% menyatakan bapak berperan mengasuh dan pemberian makan. Perilaku kader dalam penerapan PMBA telah cukup baik. Tidak ditemukan perbedaan penerapan PMBA pada kader yang telah dengan yang belum dilatih.
MODERN PROBLEMS OF CRIMINALISTIC METHODOLOGY IN THE LIGHT OF PROFESSOR N.P. YABLOKOVA
Authors: Тишутина И.В. 
Published: April 2023

В статье в контексте идей Н. П. Яблокова, изложенных в книге «Криминалистическая методика расследования: история, современное состояние и проблемы», характеризуются изменения, происходящие в преступной среде вследствие всеобщей цифровой трансформации, обусловливающие целесообразность модификации научных взглядов и подходов к организации исследования вопросов методики раскрытия и расследования отдельных видов и групп преступлений, и использование их результатов в раскрытии и расследовании преступлений. Обращается внимание на необходимость повышения эффективности деятельности правоохранительных органов в новых условиях. Отмечается, что наиболее ярко проблемы развития криминалистической методики в целом видны на примере методики расследования организованной преступной деятельности. В целях решения наиболее острых и актуальных из них предлагаются рекомендации, учитывающие современное состояние науки и техники.
The article in the context of ideas of N. P. Yablokov stated in the book "Criminalistics Investigation Techniques: History, Current State and Problems" describes changes taking place in the criminal environment due to the overall digital transformation that make it expedient to modify scientific views and approaches to research organization of techniques for detection and investigation of certain types and groups of crimes, and the use of their results in revealing and investigating of crimes. Attention is drawn to the need to improve the effectiveness of law enforcement agencies in the new environment. It is noted that problems of development of criminalistic methodology in general are most clearly seen on the example of methodology of investigation of organized crime. In order to solve the most acute and urgent of them are offered recommendations that consider the current state of science and technology.
GENERIC FORENSIC CHARACTERIZATION OF CRIMES INFRINGING ON RELATIONS IN THE FIELD OF SPORTS, ACCOMPANYING TRAINING AND COMPETITIVE RELATIONS
Authors: Пивоваров Ф.Ю. 
Published: April 2023

К текущему моменту преступность в сфере физической культуры и спорта мало изучена, а большинство научных исследований посвящено именно преступлениям, касающимся непосредственно соревновательно-тренировочного процесса. Мы предлагаем произвести более подробный анализ преступных посягательств, затрагивающих не непосредственно соревновательно-тренировочный процесс спортсменов и тренеров, а правоотношения, сопутствующие таковому и обусловленные широким разнообразием. Целью настоящего исследования является анализ особенностей правоприменительной практики, результатами которого выступает выделение наиболее типичных характеристик обозначенной группы преступлений на основе современной структуры криминалистической характеристики. На основе результатов указанного анализа нами предложены положения самостоятельной родовой криминалистической характеристики указанной группы преступлений, включающие типичные способы преступлений, особенности типичного преступника, объекты, содержащие криминалистически значимую информацию, ряд типичных обстоятельств, которые, по нашему мнению, могут быть установлены прежде всего в результате назначения и производства разного рода судебных экономических экспертиз, а также непосредственный объект преступлений.
To date, crime in the field of physical culture and sports has been little studied, and most of the scientific research is devoted specifically to crimes related directly to the competitive and training process. We propose to make a more detailed analysis of criminal encroachments that affect not directly the competitive and training process of athletes and coaches, but the legal relations that accompany it and are due to a wide variety. The purpose of this study is to analyze the features of law enforcement practice, the results of which are the selection of the most typical characteristics of a designated group of crimes based on the modern structure of forensic characteristics. Based on the results of this analysis, we propose the provisions of an independent generic forensic characterization of this group of crimes, including typical methods of crimes, features of a typical criminal, objects containing forensically significant information, a number of typical circumstances that, in our opinion, can be established primarily as a result of the appointment and the production of various kinds of forensic economic examinations, as well as the direct object of crimes.
THE POSSIBILITIES OF MODERN FORENSIC METHODS AND DNA ANALYSIS IN DETERMINING THE AGE OF A SUBJECT
Authors: Харченко И.В. , Гераськин М.Ю. , Шеков А.А. , Земляков А.В. 
Published: April 2023

Статья посвящена проблеме установления возраста задержанных по подозрению в совершении преступления, которые не имеют документов, удостоверяющих личность, либо имеющиеся у данных лиц документы являются фальшивыми, когда использование существующих криминалистических учетов, ведущихся в системе МВД России, не даёт положительного результата.
The article deals with the problem of establishing the age of persons arrested on suspicion of committing a crime, who have no identity documents or whose documents are false, when the use of existing criminal records kept in the system of the Russian Ministry of Internal Affairs does not give a positive result.