bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Concept of Sustainable Development
Authors: Fischer Manuel , Foord Daniel , Frecè Jan , Hillebrand Kirsten , Kissling-Näf Ingrid , Meili Rahel , Peskova Marie , Risi David , Schmidpeter René , Stucki Tobias 
Published: May 2023

AbstractThere are various definitions of sustainable development. However, none is as widely accepted as the one published in 1987 in the report Our Common Future. When we speak of sustainable development, we usually mean the three dimensions of nature, society and economy. These cannot be separated, but seen as elements of a holistic system. Sufficiency, efficiency and consistency are three elementary approaches for a society within planetary boundaries. Since 2015, the Agenda 2030 with its 17 Sustainable Development Goals has provided us with a widely used reference framework for global sustainable development.
Policy Instruments and Financial System
Authors: Fischer Manuel , Foord Daniel , Frecè Jan , Hillebrand Kirsten , Kissling-Näf Ingrid , Meili Rahel , Peskova Marie , Risi David , Schmidpeter René , Stucki Tobias 
Published: May 2023

AbstractThis chapter introduces negative externalities, i.e., costs incurred by a third party without the polluter having to pay compensation, and exemplifies them by external costs of transport in Switzerland. Next, the chapter compares various policy instruments the state can use to address market failures in dealing with externalities. Finally, the role of the financial system is discussed, which can counteract the current market failure in connection with externalities via sustainable measures in the area of investment and lending.
Multipotent Embryonic Lung Progenitors: Foundational Units of In Vitro and In Vivo Lung Organogenesis
Authors: Ikonomou Laertis , Yampolskaya Maria , Mehta Pankaj 
Published: May 2023

AbstractTransient, tissue-specific, embryonic progenitors are important cell populations in vertebrate development. In the course of respiratory system development, multipotent mesenchymal and epithelial progenitors drive the diversification of fates that results to the plethora of cell types that compose the airways and alveolar space of the adult lungs. Use of mouse genetic models, including lineage tracing and loss-of-function studies, has elucidated signaling pathways that guide proliferation and differentiation of embryonic lung progenitors as well as transcription factors that underlie lung progenitor identity. Furthermore, pluripotent stem cell-derived and ex vivo expanded respiratory progenitors offer novel, tractable, high-fidelity systems that allow for mechanistic studies of cell fate decisions and developmental processes. As our understanding of embryonic progenitor biology deepens, we move closer to the goal of in vitro lung organogenesis and resulting applications in developmental biology and medicine.
The Limits of Green Finance in Fossil-Based Emerging Economies—Lessons Beyond South Africa
Authors: Neumann Manuel 
Published: May 2023

AbstractWhat do the findings imply? In this chapter, I situate the seven empirical findings developed in the previous chapter within the theoretical debates around Cultural Political Economy, financialization, and Transition Studies. After grounding these findings and demonstrating their significance for debates on finance-driven transition endeavors, I zoom out into the wider implications of green bond diffusion in South Africa and beyond. In the end, I discuss potential remedies to the shortcomings of green bonds and point out avenues for further research.
Dynamical Cobordism Conjecture: solutions for end-of-the-world branes
Authors: Blumenhagen Ralph , Kneißl Christian , Wang Chuying 
Published: May 2023

Abstract
We analyze finite size solutions for a generalized D-dimensional Dudas-Mourad (DM) model featuring dynamical cobordism with neutral and charged end-of-the-world (ETW) defect branes. Confirming a dynamical version of the Cobordism Conjecture, we explicitly construct non-isotropic solutions for the latter codimension one branes and show the appearance of a lower bound $$ \delta \ge 2\sqrt{\left(D-1\right)/\left(D-2\right)} $$
δ
≥
2

D
−
1

/

D
−
2

for the critical exponent in the scaling behavior of the distance and the curvature close to the wall. This allows us to make a connection to the (sharpened) Swampland Distance Conjecture and the (Anti-) de Sitter Distance Conjecture. Moreover, BPS orientifold planes appear as special cases in our analysis and the whole picture is consistent with dimensional reduction from ten to D dimensions. An analogous analysis is performed for a generalized Blumenhagen-Font (BF) model featuring neutral codimension two ETW-branes where the same lower bound for the scaling parameter δ arises.
A supersymmetric nonlinear sigma model analogue of the ModMax theory
Authors: Kuzenko Sergei M. , McArthur I. N. 
Published: May 2023

Abstract
A decade ago, it was shown that associated with any model for U(1) duality-invariant nonlinear electrodynamics there is a unique U(1) duality-invariant supersymmetric nonlinear sigma model formulated in terms of chiral and complex linear superfields. Here we study the $$ \mathcal{N} $$
N
= 1 superconformal σ-model analogue of the conformal duality-invariant electrodynamics known as the ModMax theory. We derive its dual formulation in terms of chiral superfields and show that the target space is a Kähler cone with U(1) × U(1) being the connected component of the isometry group.
Lightlike reduction of the M5 brane
Authors: Gustavsson Andreas 
Published: May 2023

Abstract
We obtain a Lagrangian for a lightlike dimensional reduction of the nonabelian M5 brane theory in six dimension. We assume that the six-manifold has at least one conformal Killing spinor and two commuting lightlike Killing vector fields, and we perform the dimensional reduction along one of these lightlike directions.
On z-dominance, shift symmetry and spin locality in higher-spin theory
Authors: Didenko V. E. , Korybut A. V. 
Published: May 2023

Abstract
The paper aims at the qualitative criterion of higher-spin locality. Perturbative analysis of the Vasiliev equations gives rise to the so-called z-dominated non-localities which nevertheless disappear from interaction vertices leaving the final result spin-local in all known cases. This has led one to the z-dominance conjecture that suggests universality of the observed cancellations. Here we specify conditions which include observation of the higher-spin shift symmetry and prove validity of this recently proposed conjecture. We also define a class of spin-local and shift-symmetric field redefinitions which is argued to be the admissible one with respect to spin-locality.
Lightest Higgs boson decays h → MZ in the μ from ν supersymmetric standard model
Authors: Liu Chang-Xin , Zhang Hai-Bin , Yang Jin-Lei , Zhao Shu-Min , Feng Tai-Fu 
Published: May 2023

Abstract
We study the lightest Higgs boson decays h → MZ in the μ from ν supersymmetric standard model (μνSSM), where M is a vector meson (ρ, ω, ϕ, J/Ψ, Υ). Compared to the minimal supersymmetric standard model (MSSM), the μνSSM introduces three right-handed neutrino superfields, which lead to the mixing of the Higgs doublets with the right-handed sneutrinos. The mixing affects the lightest Higgs boson mass and the Higgs couplings. In suitable parameter space, the μνSSM can give large new physics (NP) contributions to the signal strengths of h → MZ and h → γγ, which may be detected by a 100 TeV collider or the other future high energy colliders.
Approximation of Uncoupled Quasi-Static Thermoelasticity Solutions Based on Gaussians
Authors: Lanzara Flavia , Maz’ya Vladimir , Schmidt Gunther 
Published: May 2023

AbstractA fast approximation method to three dimensional equations in quasi-static uncoupled thermoelasticity is proposed. We approximate the density via Gaussian approximating functions introduced in the method approximate approximations. In this way the action of the integral operators on such functions is presented in a simple analytical form. If the density has separated representation, the problem is reduced to the computation of one-dimensional integrals which admit efficient cubature procedures. The comparison of the numerical and exact solution shows that these formulas are accurate and provide the predicted approximation rate $$2,4,6$$

2
,
4
,
6

and $$8$$

8

.
Limited medial posterior capsular release increases the intraoperative medial component gap while maintaining the joint varus angle at extension in posterior‐stabilized total knee arthroplasty
Authors: Katagiri Hiroki , Saito Ryusuke , Shioda Mikio , Jinno Tetsuya , Watanabe Toshifumi 
Published: May 2023

AbstractPurposeThere is a lack of robust evidence for the magnitude of the effects of posterior capsular release (PCR) on intraoperative component gaps during total knee arthroplasty (TKA). The purpose of the present study was to quantify and compare the effects of partial versus full PCR on the intraoperative component gaps at various degrees of flexion during posterior‐stabilized TKA.MethodsFull PCR was performed on 39 consecutive cases (full PCR group), and partial PCR (the medial side up to and including the intercondylar notch) was performed on the subsequent 39 consecutive cases (partial PCR group) during posterior‐stabilized TKA using the measured resection technique for varus knee osteoarthritis. Medial component gaps and varus angles at 0°, 10°, 45°, 90°, and a maximum of flexion were measured with a tensor device before and after the PCR. Differences between the two groups in post‐release medial component gap increase and post‐release joint varus angle increase were assessed using a t test. Pre‐ to post‐release medial component gaps and joint varus angles in each group were compared using a paired samples t test.ResultsIn both groups at 0° and 10° of flexion, post‐release medial compartment gaps were significantly greater than pre‐release gaps (all P < 0.001). At 45°, 90° and maximum flexion, the medial compartment gap increase did not exceed the minimal detectable change in either group. At 0° and 10° of flexion, there was no significant difference in post‐release medial compartment gap change between the two groups. In the full PCR group, post‐release joint varus angles at 0° of flexion were significantly greater than pre‐release angles (P < 0.001), while there was no significant pre‐ and post‐release difference in the partial PCR group. The change in post‐release joint varus angles at 0° of flexion was significantly greater in the full PCR group than in the partial PCR group.ConclusionBoth full and partial PCR show similar clinical usefulness for increasing the medial component gap at extension and reducing component gap mismatch. A partial PCR can be used to avoid increasing joint varus angles at 0° of flexion.Level of evidenceLevel 2 (prospective comparative study).
Effects of bisphenol F, bisphenol S, and bisphenol AF on cultured human osteoblasts
Authors: García-Recio E. , Costela-Ruiz V. J. , Melguizo-Rodríguez L. , Ramos-Torrecillas J. , Illescas-Montes R. , De Luna-Bertos E. , Ruiz C. 
Published: May 2023

AbstractBisphenol A (BPA) analogs, like BPA, could have adverse effects on human health including bone health. The aim was to determine the effect of BPF, BPS and BPAF on the growth and differentiation of cultured human osteoblasts. Osteoblasts primary culture from bone chips harvested during routine dental work and treated with BPF, BPS, or BPAF for 24 h at doses of 10–5, 10–6, and 10–7 M. Next, cell proliferation was studied, apoptosis induction, and alkaline phosphatase (ALP) activity. In addition, mineralization was evaluated at 7, 14, and 21 days of cell culture in an osteogenic medium supplemented with BP analog at the studied doses. BPS treatment inhibited proliferation in a dose-dependent manner at all three doses by inducing apoptosis; BPF exerted a significant inhibitory effect on cell proliferation at the highest dose alone by an increase of apoptosis; while BPAF had no effect on proliferation or cell viability. Cell differentiation was adversely affected by treatment with BPA analogs in a dose-dependent, observing a reduction in calcium nodule formation at 21 days. According to the results obtained, these BPA analogs could potentially pose a threat to bone health, depending on their concentration in the organism.
Comparative sedimentation equilibrium analysis of two IgG1 glycoforms: IgGCri and IgGWid
Authors: Abu Hammad Khalil , Dinu Vlad , MacCalman Thomas E. , Pattem Jacob , Goodall Margaret , Gillis Richard B. , Jefferis Roy , Harding Stephen E. 
Published: May 2023

AbstractThe solution properties of two different glycoforms of IgG1 (IgG1Cri and IgG1Wid) are compared using primarily sedimentation equilibrium analysis with two complementary analysis routines: SEDFIT-MSTAR and MULTISIG. IgGCri bears diantennary complex-type glycans on its Fc domain that are fully core fucosylated and partially sialylated, whilst on IgGWid, they are non-fucosylated, partially galactosylated and non-sialylated. IgGWid is also Fab glycosylated. Despite these differences, SEDFIT-MSTAR analysis shows similar weight average molar masses Mw of ~ (150 ± 5) kDa for IgGCri and ~ (154 ± 5) kDa for IgGWid and both glycoforms show evidence of the presence of a small fraction of dimer confirmed by MULTISIG analysis and also by sedimentation coefficient distributions from supportive sedimentation velocity measurements. The closeness of the sedimentation equilibrium behaviour and sedimentation coefficient distributions with a main peak sedimentation coefficient of ~ 6.4S for both glycoforms at different concentrations suggest that the different glycosylation profiles do not significantly impact on molar mass (molecular weight) nor conformation in solution.
Evaluating the Social Impact of a Proposed Orthopedic Center of Excellence in Northern Tanzania: A Novel Use of the Impact Multiple of Money Methodology
Authors: Thota Praneeth , Dravid Avi , Ramesh Sireesh , Massawe Honest , Sheth Neil P. 
Published: May 2023

AbstractBackgroundMusculoskeletal injuries—often a result of Road Traffic Accidents (RTAs)—represent a significant burden in sub‐Saharan Africa. RTA victims are faced with lifelong disability and diminished employment. Northern Tanzania in particular lacks the orthopedic surgical capacity needed to provide patients with definitive surgical fixation. While there is great potential in establishing an Orthopedic Center of Excellence (OCE), the precise social impact of such an initiative is currently unknown.MethodsTo demonstrate the social value of an orthopedic OCE in Northern Tanzania, this paper proposes a methodology for calculating social impact. This methodology draws upon RTA‐related Disability Adjusted Life Years (DALYs), current and projected surgical complication rates, anticipated changes in surgical volume, and average per capita income to quantify how much social value can be gained by mitigating the impact of RTAs. These parameters can be utilized to calculate an impact multiplier of money (IMM), stating the social returns on each dollar invested.ResultsModeling exercises demonstrate that improvements in the complication rate and surgical volume over the current baseline results in significant social impact. In the best‐case scenario, the COE is expected to yield over $131 million over 10 years, with an IMM of 13.19.ConclusionsInvestments in orthopedic care will yield significant dividends, as demonstrated by our novel methodology. The cost‐effectiveness of the OCE is comparable to, if not greater, than many other global health initiatives. More broadly, the IMM methodology can be used to quantify the impact of other projects aimed at reducing long‐term injury.
Changing nationwide trends away from overtreatment among patients undergoing radical prostatectomy over the past 25 years
Authors: Meissner Valentin H. , Glöckler Viviane , Jahnen Matthias , Schiele Stefan , Gschwend Jürgen E. , Herkommer Kathleen 
Published: May 2023

Abstract
Purpose
The objective of the current study was to assess whether and how preoperative risk group distribution and pathological outcomes have changed in men treated with radical prostatectomy (RP) over the past 25 years.

Methods
11,071 patients from a large contemporary registry-based nationwide cohort with RP as primary treatment between 1995 and 2019 were included. Preoperative risk stratification, postoperative outcomes, and 10 years other-cause mortality (OCM) were analyzed.

Results
After 2005, the proportion of low-risk prostate cancer (PCa) decreased from 39.6% to 25.5% in 2010 and decreased further to 15.5% in 2015, and 9.4% in 2019 (p < 0.001). The proportion of high-risk cases increased from 13.1% in 2005 to 23.1% in 2010 and 36.7% in 2015, and 40.4% in 2019 (p < 0.001). After 2005, the proportion of cases with favorable localized PCa decreased from 37.3% to 24.9% in 2010 and decreased further to 13.9% in 2015, and 1.6% in 2019 (p < 0.001). The overall 10 years OCM was 7.7%.

Conclusion
The current analysis documents a clear shift in utilization of RP toward higher-risk PCa in men with long life expectancy. Patients with low-risk PCa or favorable localized PCa are rarely operated. This suggests a shift in applying surgery only to patients who may really benefit from RP and the long-standing discussion of overtreatment might become outdated.
Histochemistry and Cell Biology—a glance into the past and a look ahead
Authors: Roth Jürgen , Taatjes Douglas J. 
Published: May 2023

AbstractAt the occasion of the 65th anniversary of Histochemistry and Cell Biology, we browse through its first ten years of publication and highlight a selection of papers from the early days of enzyme, protein, and carbohydrate histochemistry. In addition, we narrate recent progress to identify, quantify, and precisely determine the tissue localization of proteins and lipids, and small molecules by the combination of spectroscopic techniques and histology.
Efficacy of exercise interventions for women during and after gynaecological cancer treatment – a systematic scoping review
Authors: Rose Grace Laura , Stewart Elizabeth Mary , Clifford Briana Kristine , Bailey Tom George , Rush Alexandra Jane , Abbott Claudia Rose , Hayes Sandra Christine , Obermair Andreas , McCarthy Alexandra Leigh 
Published: May 2023

Abstract
Purpose
To systematically synthesise evidence of exercise intervention efficacy for physical/psychosocial outcomes that matter to women during/following treatment for gynaecological cancer.

Methods
Five databases were searched (PubMed, EMBASE, CINAHL, PsychInfo, Scopus). Exercise-only intervention studies that included women during/ following treatment for any gynaecological cancer, with/ without control comparison, on any physical or psychosocial outcome(s), were included and qualitatively appraised using the Revised Cochrane Risk of Bias tool and a modified Newcastle-Ottawa Scale.

Results
Seven randomised controlled trials (RCTs), three single-arm pre-post studies, and one prospective cohort study satisfied were included (11 studies). Most studies were completed following treatment (91%), included combined (aerobic and resistance; 36%) and aerobic (36%) training, were fully/mostly (63%) unsupervised, and had a moderate-to-high risk of bias. Overall, 33 outcomes (64% objectively-measured) were assessed. Improvements were observed in aerobic capacity (V̇O2 Peak +1.6 mL/kg/min, 6-minute walk distance +20-27 m), lower- (30-second sit-to-stand +2-4 repetitions) and upper-limb strength (30-second arm curl +5 repetitions; 1RM grip strength/chest press +2.4-3.1 kg), and agility (timed up-and-go -0.6 seconds). However, changes in quality of life, anthropometry/body composition, balance and flexibility were inconsistent. There was no evidence to support worsening of outcomes.

Conclusion
Preliminary research into the role of exercise post-gynaecological cancer suggests an improvement in exercise capacity, muscular strength, and agility which, in the absence of exercise, typically decline following gynaecological cancer. Future exercise trials involving larger and more diverse gynaecological cancer samples will improve understanding of the potential and magnitude of effect of guideline-recommended exercise on outcomes that matter to patients.
Knowledge guided multi-filter residual convolutional neural network for ICD coding from clinical text
Authors: Boukhers Zeyd , Goswami Prantik , Jürjens Jan 
Published: May 2023

AbstractA common challenge encountered when using Deep Neural Network models for automatic ICD coding is their potential inability to effectively handle unseen clinical texts, especially when these models are only trained on a limited number of examples. This is because these models rely solely on the patterns and relationships present in the training data, and may not be able to effectively incorporate additional knowledge about the relationships between medical entities. To address this issue, we introduce KG-MultiResCNN—KnowledgeGuidedMulti-filterResidualConvolutionalNeuralNetwork model, which combines training examples with external knowledge from the Wikidata Knowledge Graph (KG) in order to better capture the relationships between medical entities. The KG is a structured database that contains a wealth of information about various entities, including medical concepts and their relationships with one another. By incorporating this external knowledge into our model, we are able to improve its ability to predict ICD codes for new clinical texts. In our experiments with the MIMIC-III dataset, we found that the KG-MultiResCNN model significantly outperformed the baseline approaches. This demonstrates the effectiveness of using external knowledge, in addition to training examples, to improve the performance of deep learning models for automatic ICD coding.
Optimal energy planning of multi-microgrids at stochastic nature of load demand and renewable energy resources using a modified Capuchin Search Algorithm
Authors: Ebeed Mohamed , Ahmed Deyaa , Kamel Salah , Jurado Francisco , Shaaban Mostafa F. , Ali Abdelfatah , Refai Ahmed 
Published: May 2023

AbstractThe concept of interconnected multi-microgrids (MMGs) is presented as a promising solution for the improvement in the operation, control, and economic performance of the distribution networks. The energy management of the MMGs is a strenuous and challenging task, especially with the integration of renewable energy resources (RERs) and variation in the loading due to the intermittency of these resources and the stochastic nature of the load demand. In this regard, the energy management of the MMGs is optimized with optimal inclusion of a hybrid system consisting of a photovoltaic (PV) and a wind turbine (WT)-based distributed generation (DGs) under uncertainties of the generated powers and the load variation. A modified Capuchin Search Algorithm (MCapSA) is presented and applied for the energy management of the MMGs. The MCapSA is based on enhancing the searching abilities of the standard Capuchin Search Algorithm (CapSA) using three improvement strategies including the quasi-oppositional-based learning (QOBL), the random movement-based Levy flight distribution, and the exploitation mechanism of the prairie dogs in the prairie dog optimization (PDO). The optimized function is a multi-objective function that comprises of the cost and the voltage deviation reduction along with stability enhancement. The effectiveness of the proposed technique is verified on standard benchmark functions and the obtained results. Then, the proposed method is used for energy management of IEEE 33-bus and 69-bus MMGs at uncertainties conation. The results depict that the energy management with inclusion of WTs and PVs using the proposed technique can reduce the cost and summation of the VD by 46.41% and 62.54%, and the VSI is enhanced by 15.1406% for the first MMG. Likewise, for the second MMG, the cost and summation of the VD are reduced by 44.19% and 39.70%, and the VSI is enhanced by 4.49%.