bluuebunny/crossref_metadata_2025_split huggingface dataset:
UV photoluminescence in lycaenid butterfly larvae and implications for nocturnal monitoring
Authors: Tilley Gareth J. , Stewart Alan J. A. 
Published: January 2025

Abstract
Nocturnal ultraviolet (UV) flashlight surveys offer a valuable method for investigating butterfly species with cryptic larvae. Focusing on the Lycaenidae, we address three fundamental questions to inform the design of such surveys and the wider significance of this phenomenon. Do the larvae of all species photoluminesce? Which larval instars photoluminesce and how can this information be used to help determine the optimum timeframe in which to search for larvae in the field? Is the level of photoluminescence in different species affected by the UV wavelength used?
Thirteen species of lycaenid butterfly across three subfamilies were tested for photoluminescence in response to UV flashlight. Eight species photoluminesced strongly under 365 nm compared to six under 385–395‐nm UV light. Five species exhibited no photoluminescent response to either wavelength. Neither ova nor pupae of any species tested photoluminesced.
Photoluminescence in Satyrium pruni (Black Hairstreak) larvae increased with larval stage under controlled laboratory conditions. A similar effect was found in other species of Theclinae but was initiated at different stages.
When monitoring lycaenid larvae, it is recommended that a 365 nm flashlight is trialled first and researchers consider when photoluminesce properties develop in larvae when assessing the optimum timeframe for conducting surveys.
Real options investments: Lessons from the US shale gas industry
Authors: Elbakidze Levan , Mugabe Douglas , Zaynutdinova Gulnara R. 
Published: January 2025

AbstractUsing detailed project‐level investment data from the U.S. upstream natural gas industry, we examine the effect of the unexercised real options on individual firms’ real options investments. Drilling an unconventional well is a real options investment that is exercised by fracturing and completing the drilled well at an opportune time. We find a small negative but statistically significant effect of the number of unexercised options on real options investments. There is also a significant difference in the effect of unexercised real options on real options investment decisions of publicly traded and privately held firms.
Hepatitis C Treatment With Generic Sofosbuvir‐Based Regimens in Patients Undergoing Hemodialysis
Authors: Afredj Nawal , Boumendjel Mustapha , Mahiou Hassen , Drir Othmane , Cheikh Ibtissem Ouled , Belimi Hibatallah , Kerbouche Rafik , Guessab Nawal , Zaidi Arezki , Boutra Fouad , Nakmouche M'hamed , Debzi Nabil 
Published: January 2025

ABSTRACTObjectivesTo assess the efficacy and safety of locally manufactured generic sofosbuvir‐based direct‐acting antivirals in the treatment of Hepatitis C virus (HCV) infected patients on maintenance hemodialysis.Patients and MethodsWe have conducted a retrospective multicenter study including patients on maintenance hemodialysis, treated with sofosbuvir‐based regimens between 01/01/2017 and 09/30/2021. Patients were treated for 12 or 24 weeks, with sofosbuvir 400 mg + ledipasvir 90 mg 3 times/week, or sofosbuvir 3 times/week + daclatasvir 60 mg/d, or sofosbuvir + daclatasvir in coformulation, 3 times/week. Sustained virological response was defined as a negative HCV RNA test 12 weeks after treatment. The occurrence of serious adverse events during treatment defines intolerance to treatment. Statistical analysis was performed using SPSS software (version 25).ResultsA total of 120 patients were treated; the mean age was 50 ± 14.17 years [18–78], 50% were men. Twenty‐two patients (n = 22; 18.3%) were previously treated with pegylated Interferon. Genotype 1 was predominant (n = 68; 82%). Most of the patients (n = 53; 44.2%) had no significant fibrosis, and 24 (20%) had cirrhosis. The SVR rate was 93.3% (CI 95% [88.8; 97.8]) (n = 112), the serious adverse events rate was 10.8% (CI 95% [0.054–0.166]) (n = 13), including 2 deaths unrelated to direct‐acting antivirals. Early treatment discontinuation occurred in 5.8% (n = 7), and a relapse in 0.8% (n = 1). On multivariate analysis, risk factors for serious adverse events included advanced liver fibrosis, thrombocytopenia, hypoalbuminemia, high bilirubin level, and pre‐treatment status.ConclusionLocally manufactured generic sofosbuvir‐based regimens are safe and effective in maintenance hemodialysis patients. However, they should be closely monitored to manage comorbidities and complications during treatment.
Consumer Decision‐Making Processes Regarding Healthy Food Choices: A Systematic Literature Review and Future Research Agenda
Authors: Shah Priya , Mahajan Harleen , Sompura Nidhi H. , Sunil Anitha , Naldurgakar Rucha 
Published: January 2025

ABSTRACTThis study systematically reviews the literature on consumer perceptions of healthy food choices, employing the ADO (Antecedents, Decisions, Outcomes) framework to analyze 118 peer‐reviewed articles. The research identifies significant inconsistencies in consumer definitions and understanding, influenced by evolving scientific knowledge and diverse information cues. These challenges highlight critical research gaps and underscore the need for strategic marketing interventions and consumer segmentation based on these evolving perceptions. The review proposes a conceptual framework that elucidates the complex interplay between antecedents, decisions, and outcomes in dietary behaviors. The findings aim to empower consumers with evidence‐based strategies for informed dietary choices, contributing to improved public health outcomes. By consolidating fragmented research, this study offers valuable insights for practitioners and policymakers to develop effective marketing strategies and public health initiatives that encourage healthier eating habits.
Enhancing oocyte competence in patients with polycystic ovarian syndrome: A microfluidic study on the effects of follicular fluid meiosis‐activating sterol in in vitro oocyte maturation
Authors: Torkashvand Hossein , Shabani Ronak , Artimani Tayebe , Pilehvari Shamim , Moghimi Mahdi , Torkashvand Leila , Ashrafi Mahnaz , Mehdizadeh Mehdi 
Published: January 2025

AbstractObjectiveTo evaluate the efficacy of a microfluidic culture system supplemented with follicular fluid meiosis‐activating sterol (FF‐MAS) on the maturation of immature oocytes in patients with polycystic ovarian syndrome (PCOS).MethodsA total of 438 germinal vesicle oocytes from 163 PCOS patients were included. Oocytes were divided into five groups: (1) cultured in static drops without FF‐MAS, (2) cultured in static drops with FF‐MAS, (3) cultured in a microfluidic device without FF‐MAS, (4) cultured in a microfluidic device with FF‐MAS for the first 2 h, and (5) cultured in a microfluidic device with FF‐MAS for 24 h. Maturation, fertilization, and embryo development rates were assessed, alongside gene expression analysis using quantitative real‐time PCR. Ultrastructural analysis was performed using transmission electron microscopy (TEM).ResultsThe maturation rates for oocytes in groups 1 to 5 were 36%, 48%, 42%, 64%, and 65%, respectively, with groups 4 and 5 showing significant increases (p < 0.05). Fertilization rates were higher in groups 4 and 5 (p < 0.05). High‐quality embryo formation rates were significantly higher in groups 3, 4, and 5. Gene expression analysis indicated enhanced expression of BRCA1 and TP53 in the dynamic culture groups. Ultrastructural analysis showed improved mitochondrial integrity and cytoplasmic maturation in the dynamic groups.ConclusionsThe dynamic microfluidic culture system with FF‐MAS supplementation significantly enhances oocyte maturation and embryo quality in PCOS patients by closely mimicking the natural in vivo environment. This approach shows promise for optimizing in vitro oocyte maturation and improving fertility outcomes.
Championing new ideas with consultation
Authors: Mahaney Joshua , Gillier Thomas , Schweitzer Fiona 
Published: January 2025

AbstractIdea championing is key for implementing new ideas. A few research studies show that inventors use the consultation tactic to champion their new ideas inside organizations—that is, inventors ask others to contribute to their new ideas in the hope of obtaining others' commitment. However, prior research does not indicate why inventors should use consultation and when it is beneficial. This research proposes that consultation enhances psychological ownership, and that psychological ownership increases idea commitment. Additionally, we posit that the extent to which idea receivers contribute and build psychological ownership will vary depending on the format of the new idea. We hypothesize that consultation is beneficial when idea receivers are asked to contribute to low‐elaborated ideas framed in a non‐narrative format, as this type of idea format provides greater opportunities for inputs. In contrast, we argue that idea receivers build less psychological ownership when they are asked to contribute to high‐elaborated ideas and/or ideas framed in a narrative format (e.g., storytelling). An exploratory survey with 204 inventors confirms that the use of consultation for gaining idea commitment is widespread in companies. The survey shows that inventors present their new ideas at varying levels of elaboration and narrative format. Furthermore, three laboratory experiments provide strong support for our predictions. This study extends our understanding of the idea championing process by providing new insights into how consultation best fosters psychological ownership.
Transgene‐free genome editing in poplar
Authors: Hoengenaert Lennart , Anders Chantal , Van Doorsselaere Jan , Vanholme Ruben , Boerjan Wout 
Published: January 2025

Summary
Precise gene‐editing methods are valuable tools to enhance genetic traits. Gene editing is commonly achieved via stable integration of a gene‐editing cassette in the plant's genome. However, this technique is unfavorable for field applications, especially in vegetatively propagated plants, such as many commercial tree species, where the gene‐editing cassette cannot be segregated away without breaking the genetic constitution of the elite variety.
Here, we describe an efficient method for generating gene‐edited Populus tremula × P. alba (poplar) trees without incorporating foreign DNA into its genome. Using Agrobacterium tumefaciens, we expressed a base‐editing construct targeting CCoAOMT1 along with the ALS genes for positive selection on a chlorsulfuron‐containing medium.
About 50% of the regenerated shoots were derived from transient transformation and were free of T‐DNA. Overall, 7% of the chlorsulfuron‐resistant shoots were T‐DNA free, edited in the CCoAOMT1 gene and nonchimeric.
Long‐read whole‐genome sequencing confirmed the absence of any foreign DNA in the tested gene‐edited lines. Additionally, we evaluated the CodA gene as a negative selection marker to eliminate lines that stably incorporated the T‐DNA into their genome. Although the latter negative selection is not essential for selecting transgene‐free, gene‐edited Populus tremula × P. alba shoots, it may prove valuable for other genotypes or varieties.
The Interaction Between ABA and Sugar Signalling Regulates Stomatal Production in Systemic Leaves by Controlling Sucrose Transport
Authors: Yao Zi‐Meng , Shi Ya‐Na , Zou Ya‐Li , Meng Lai‐Sheng 
Published: January 2025

ABSTRACTA key feature of stress responses [closely relative to the phytohormone abscisic acid (ABA)] and associated acclimation in plants is the dynamic adjustments and related optimisation of carbohydrate content between sink and source organs. The production of stomata, which consist of a pore between two adjacent guard cells, are central to plant adaptation to changing environment conditions. In this context, ABA is a core modulator of environmentally determined stomatal development. It is well established that ABA reduces stomatal aperture but in addition, this hormone also enhances stomatal production. For example, when grown at very high CO2 levels, Arabidopsis lines with defects in ABA biosynthesis have reduced stomatal production. By contrast, under standard conditions, these ABA biosynthetic mutants show increased stomatal production. However, the molecular mechanism(s) underpinning this regulation remain largely unknown. In this review, we summarise the current knowledge concerning sucrose transport and ABA signalling relating to stomatal production. Further, we provide fresh insights into the possible function of photosynthetic product induced‐ABA as a balancer of carbohydrate accumulation between sink and source organs, to control stomatal production and thereby to adjust stress responses and acclimation in plants, by controlling sucrose transport systems.
Ancient schwannoma of the submandibular gland
Authors: Sittisak Nuttawut , Kiatmontri Jinatta , Uaangkanon Sumet , Sirimahachaiyakul Pornthep 
Published: January 2025

Schwannomas, benign tumours derived from Schwann cells, exhibit slow growth rates and are commonly found extracranially in the head, neck and extremities. However, intraoral and salivary gland schwannomas are less frequent. Ancient schwannomas, characterised by histological degenerative changes, represent a rare variant.This report pertains to a case study involving a man in his 40s who presented with a slow, progressive and painless mass in the right submandibular region persisting over 3 years.CT revealed a well-defined multiloculated cystic mass in the right submandibular gland, later confirmed as an ancient schwannoma on excision and histological examination. Immediate postoperative complications included right marginal mandibular nerve palsy, fully resolving within 12 months. No recurrent tumours were detected in subsequent physical examinations and imaging.Ancient schwannomas, although rare, can occur in the submandibular gland. Thorough multimodal diagnostic approaches are essential for accurate differentiation from other submandibular masses.
Neurodevelopmental outcomes after infant heart surgery for congenital heart disease: a hospital-based multicentre prospective cohort study from India
Authors: Raj Manu , Chattopadhyay Amitabha , Gupta Saurabh Kumar , Jain Shreepal , Sastry Usha M K , Sudevan Remya , Sharma Meenakshi , Pragya Pragati , Shivashankar Roopa , Sudhakar Abish , Radhakrishnan Anjana , Parveen Sana , Patil Sakshi , Naik Shamika , Das Shilpa , Kumar Raman Krishna 
Published: January 2025

BackgroundNeurodevelopmental disability is a common long-term concern following surgery for congenital heart disease (CHD). Little information is available from low-resource environments where the majority of children with CHD are born. Several challenges in the CHD care continuum exist in such environments.MethodsWe followed 1346 infants who were operated for CHD using cardiopulmonary bypass from five paediatric cardiac programmes across India. The neurodevelopmental assessment was done using the Developmental Assessment Scale for Indian Infants (DASII) at 6 months after surgery.ResultsA total of 1145 (94.8%) infants were alive at 6 months and 127 (11.1%) were lost to follow-up. The mean age of participants at baseline was 5.2 (3.6) months. The mean motor developmental quotient (DMoQ) and mental developmental quotient (DMeQ) of the remaining 1018 infants were 81.8 (69.5, 93.0) and 87.7 (77.1, 95.7), respectively. A total of 262 (25.7%) infants had motor developmental delay and 157 (15.4%) had mental developmental delay. Syndromic association, younger age at surgery, duration of mechanical ventilation and head circumference were significantly associated with DMoQ. The DMeQ was associated with syndromes, duration of hospital and intensive care unit stay and socioeconomic status. The preoperative condition did not impact mental and motor development. Motor clusters with maximum delay included body control and locomotion. Mental clusters with maximum delay included reaching and manipulation, social interaction-imitative behaviour and vocabulary comprehension.ConclusionsSurvivors of infant heart surgery experience significant motor and mental neurodevelopmental delay. This delay is associated with similar factors reported by earlier studies. As more high-risk infants undergo cardiac surgery in low-resource settings, a growing population will require significant societal resources for neurodevelopmental assessment as well as neurodevelopmental rehabilitation. These resources include trained personnel for comprehensive developmental assessment of survivors of CHD surgery, as well as infrastructural requirements for dedicated assessment rooms in centres providing surgical care for CHD patients.
Interplay of chiral transitions in the standard model
Authors: Gies Holger , Schmieden Richard , Zambelli Luca 
Published: January 2025

Abstract
We investigate nonperturbative aspects of the interplay of chiral transitions in the standard model in the course of the renormalization flow. We focus on the chiral symmetry breaking mechanisms provided by the QCD and the electroweak sectors, the latter of which we model by a Higgs-top-bottom Yukawa theory. The interplay becomes quantitatively accessible by accounting for the fluctuation-induced mixing of the electroweak Higgs field with the mesonic composite fields of QCD. In fact, our approach uses dynamical bosonization and treats these scalar fields on the same footing. Varying the QCD scale relative to the Fermi scale we quantify the mutual impact of the symmetry-breaking mechanisms, specifically the departure from the second order quantum phase transition of the pure Yukawa sector in favor of a crossover upon the inclusion of the gauge interactions. This allows to discuss the “naturalness” of the standard model in terms of a pseudo-critical exponent which we determine as a function of the ratio of the QCD and the Fermi scale. We also estimate the minimum value of the W boson mass in absence of the Higgs mechanism.
$$\varLambda $$CDM model against gravity-thermodynamics conjecture: observational constraints after DESI 2024
Authors: Shahhoseini N. , Malekjani M. , Khodam-Mohammadi A. 
Published: January 2025

Abstract
In the context of the gravity-thermodynamics conjecture based on the Tsallis entropy-area relation, we investigate the standard

$$\varLambda $$

Λ

CDM cosmology and examine some potential deviations from it. Utilizing recent updates from geometrical datasets, including the DESI BAO measurements (2024), Planck CMB anisotropy measurements (2018), and the Pantheon+ catalogue for SNIa (2022), we conduct a thorough analysis via the window of Tsallis cosmology. In the first step, our analysis reveals no significant deviation from the standard model when using DESI BAO data alone, Pantheon+ data alone, or a combination of both. In the next step, we incorporate all datasets by adding the CMB data to our analysis, indicating a potential deviation from the standard model within the framework of Tsallis cosmology. Imposing the Planck prior to the sound horizon at the baryon drag epoch, we observe support for the standard model and consistency between our constraints on the Hubble constant and the Planck value. Finally, we compare the Tsallis and

$$\varLambda $$

Λ

CDM cosmologies using the Akaike Information Criterion (AIC).
Hypotensive Episodes Identified on 24-Hour Ambulatory Blood Pressure and Impaired Cognitive Function: Insights From the SPRINT Study
Authors: Zhang Wenxin , Redline Susan , Viswanathan Anand , Ascher Simon B. , Hari Darshana , Juraschek Stephen P. , Tzourio Christophe , Drawz Paul E. , Lipsitz Lewis A. , Mittleman Murray A. , Ma Yuan 
Published: January 2025

BACKGROUND:
Hypotensive episodes detected by 24-hour ambulatory blood pressure (BP) monitoring capture daily cumulative hypotensive stress and could be clinically relevant to cognitive impairment, but this relationship remains unclear.

METHODS:
We included participants from the Systolic Blood Pressure Intervention Trial (receiving intensive or standard BP treatment) who had 24-hour ambulatory BP monitoring measured near the 27-month visit and subsequent biannual cognitive assessments. We evaluated the associations of hypotensive episodes (defined as systolic BP drops of ≥20 mm Hg between 2 consecutive measurements that reached <100 mm Hg) and hypotensive duration (cumulative time of systolic BP <100 mm Hg) with subsequent cognitive function using adjusted linear mixed models. We further assessed 24-hour average BP and variability.

RESULTS:

Among 842 participants with treated hypertension (mean age, 71±9 years; 29% women), the presence (versus absence) of recurrent hypotensive episodes (11%) was associated with lower digit symbol coding scores (difference in
Z
scores, −0.249 [95% CI, −0.380 to −0.119]) and faster declines (difference in
Z
score changes, −0.128 [95% CI, −0.231 to −0.026]). A consistent dose-response association was also observed for longer hypotensive duration with worse Montreal Cognitive Assessment and digit symbol coding scores. The association with digit symbol coding scores remained significant after further adjusting for 24-hour average BP and variability and was not observed for hypotension defined by clinic, orthostatic, or 24-hour average BP. Intensive BP treatment increased 24-hour hypotensive episodes and modified its association with the decline in digit symbol coding score.

CONCLUSION:
Twenty-four–hour hypotensive episodes were associated with worse cognitive function, especially in processing speed, and could be a novel marker for optimal BP control and dementia prevention.
Association between alkaline phosphatase levels and mortality in Chinese patients with colorectal cancer with liver metastases: a retrospective cohort study
Authors: Liu ZhaoXi , Zhang ZiQing , Yu GuoFang , Mo MingJiang , Xie ChuanYu , Xu DangHan , Lin JieTao , Zhang YuChen , Deng Li , Luo YiChang , Huang YingFeng , Shao Cui 
Published: January 2025

Background: Alkaline phosphatase (ALP) is a potential cancer biomarker. However, its prognostic value in patients with colorectal liver metastasis remains unclear. Objectives: This study aimed to investigate the association between ALP levels and mortality risk in patients with colorectal liver metastases (CRLM), providing insights for enhancing prognostic assessments. Design: Retrospective cohort study. Methods: This study included 195 patients with CRLM from a single centre in China. ALP level was the primary exposure variable, with demographic, clinical and pathological factors serving as covariates. Multivariate Cox regression analyses were used to evaluate the impact of ALP on mortality over a 4-year follow-up period. Covariates included the number of liver metastases, T stage, N stage, chemotherapy, tumour location, primary surgery, topical treatment, apolipoprotein A1, targeted therapy, tumour type, CA-199 levels, metastatic surgery, sex, Karnofsky Performance Status and age. Results: Of 195 enrolled patients, 134 (68.72%) were male, and 61 (31.28%) were female, with ages ranging from January 2008 to December 2019. A total of 147 patients (76.96%) were diagnosed with left hemicolon cancer and 44 (23.04%) with right hemicolon cancer. After adjusting for the covariates, elevated ALP levels were significantly associated with an increased risk of mortality (hazard ratio = 1.24, 95% confidence interval: 1.08–1.43, p = 0.0029). Sensitivity analyses confirmed the robustness of these findings, reinforcing the association across different analytical approaches. Conclusion: ALP level is a valuable prognostic indicator in patients with CRLM. Integrating ALP measurement into clinical practice may enhance risk stratification and patient management. Future research should explore the role of ALP in broader populations and explore its implications for treatment strategies.