bluuebunny/crossref_metadata_2025_split huggingface dataset:
Greenhouse Cell
Authors: Amr Gasser , Tarek Ali 
Published: July 2023

Abstract
A solution has been discovered to address the problem of
generating energy from alternative sources of greenhouse gases, taking
into account design requirements such as low cost, environmental
friendliness, and high efficiency. The experiment involved the utilization
of chemical reactions to transfer electrons, thereby generating electrical
energy while simultaneously reducing carbon dioxide levels. Carbon
dioxide was employed as a catalyst in this experiment, yielding
remarkable results. The electrical energy produced was measured using an
ammeter, and it was found to be close to 1 volt, thus meeting the desired
requirements of the solution. Throughout the experiment, diluted and
unconcentrated materials were utilized to assess their effectiveness. This
sustainable solution, which aligns with the mission to mitigate the impact
of climate change and pollution, can be presented to the world. The
energy generated through this method holds significant potential for
global implementation, given that energy serves as the backbone of our
modern society. By promoting the adoption of this solution, societies can
reduce their reliance on traditional energy sources and embrace a more
environmentally conscious approach. Furthermore, the utilization of
alternative sources of greenhouse gases contributes to the overall
reduction of air, soil, and water pollution. In summary, an experiment has
been conducted to generate electrical energy from alternative sources of
greenhouse gases. The results demonstrate the viability of this approach,
offering a sustainable solution that addresses the challenges faced by
governments worldwide. The presentation and implementation of this
solution on a global scale can pave the way for a cleaner, more energy-efficient future.
Risankizumab: a real-world Israeli data in severe refractory IBD patients
Authors: Shitrit Ariella Bar-Gil , Israeli Eran , Koslowsky Binyamin , Ben-Bassat Ofer , Ledder Oren , Weisbrud Amir , Zinger Adar , Israel Ilana , Rosalind Goldenberg , Mazuz Betty , Gil Yoel , Horin Shomron Ben , Goldin Eran , Lahat Adi 
Published: July 2023

Abstract
Background: Inflammatory bowel disease (IBD), namely Crohn’s disease (CD) and ulcerative colitis (UC), is a life-long, relapsing disease. Since resistance mechanisms are often developed, the landscape of IBD treatments is rapidly expanding. Risankizumab (Skyrizi®), an antibody targeting the p19 subunit of IL23 was shown effective in phase 3 trials for CD.
Aim: Since real-world data is scarce, we present herein a 52 week follow-up data on 33 patients with severe refractory disease who have received risankizumab as a compassionate treatment.
Methods: Prospective Israeli multicenter study on moderate-to-severe refractory IBD (28 CD, 5 UC) who received Risankizumab (IV 600-1800mg at 0, 4, 8 weeks; then SC 180 or 360mg every 8 weeks) for up to 52 weeks.
Results: 33 patients refractory to all available biologics agents were included. At week 12, there was a significant reduction in Harvey Bradshaw index (HBI) for CD and in CRP values vs. week 0 (10±6.5 to 4.9±4.2, p=0.016; 3.8±3 to 1.56±1.5, p=0.002, respectively). Mayo score for UC was also reduced (6.7±2.5 to 3±2, p=0.044, both doses, n=4). Moreover, 10/16 (62.5%) of the 180mg dose and 3/12 (25%) of the 360mg dose group achieved clinical remission, all steroid free. Additionally, 13/16 (81.3%) of the 180mg dose and 5/12 (41.7%) of the 360mg dose achieved clinical response. 4/5 UC patients showed clinical response on week 12. No serious adverse events were reported.
Conclusion: Our real-world cohort shows that risankizumab holds a great therapeutic promise, even for patients with resistant disease refractory to multiple biologics.
Whole Exome Sequencing Identifies Novel Pathogenic Variants in TGM1 and ALOX12B in Patients with Hereditary Ichthyosis
Authors: Chegini Mitra , Eslami Maryam , Motavaf Mahsa , Sadeghi Omeed Memar , Hoseini Azadeh , Torab Elnaz , Hoseininasab Fatemeh , Amiri Hosna , Ramandi Somayeh , Mostofinezhad Niusha , Keivani Fataneh , Ghaffari Saeed Reza , Rafati Maryam 
Published: July 2023

Abstract
Background
Hereditary ichthyosis is a clinically and genetically heterogeneous disorder of keratinization, characterized by cutaneous hyperkeratosis of the skin. Mutations in over 50 genes have been identified to be associated with hereditary ichthyosis. Establishing an accurate diagnosis is important for genetic counseling and patient management.
Objective
We aimed to assess the clinical applicability of whole-exome sequencing (WES) in the molecular diagnosis of hereditary ichthyosis.
Methods
During a 1-year period, index cases of 5 unrelated families clinically diagnosed with hereditary ichthyosis went through WES, followed by extensive segregation analysis to assess the pathogenicity of the detected variants, and prenatal diagnosis, where indicated.
Results
In this case series, we identified 2 homozygous variants (c.655A > G and c.797A > G) and one heterozygous (c.428G > A) variant in TGM1 and 2 homozygous variants (c.527 + 2T > G and c.1654G > T) in ALOX12B, 4 of which were novel. The variants were all pathogenic/likely pathogenic according to the ACMG classification and segregation analysis, except for c.797A > G in TGM1 which was a variant of unknown clinical significance. Prenatal diagnosis was performed in Family 1 with c.655A > G in TGM1 and Family 2 with c.527 + 2T > G in ALOX12B.
Conclusion
Our findings further support that WES is an effective diagnostic tool for the accurate and rapid identification of causative variants in hereditary ichthyosis.
The WE-RISE TM Multidomain Intervention: A feasibility study for the potential reversal of cognitive frailty in Malaysian older persons from lower socioeconomic status
Authors: Murukesu Resshaya Roobini , Shahar Suzana , Subramaniam Ponnusamy , Rasdi Hanif Farhan Mohd , Nur Amrizal Muhammad , Singh Devinder Kaur Ajit 
Published: July 2023

Abstract

Background: There is a lack of evidence regarding cognitive frailty (CF) and its potential reversibility with a multidomain intervention among older persons. This study aimed to investigate the effectiveness of the WE-RISE™ multidomain intervention in addressing the potential reversibility of CF among community-dwelling older persons from lower SES and to determine if WE-RISE™ is of low cost.Methods: This randomized controlled trial was carried out over 24 weeks among older persons with CF from lower SES. The experimental group (n=27) received the WE-RISE™ intervention comprising 12 weeks of instruction, community-based intervention and 12 weeks of WE-RISE™@Home, while the control group (n=28) received usual care. CF status, cognitive, physical, nutrition, disability, health-related quality of life, exercise self-efficacy and depression statuses were assessed at baseline and at the 12thand 24thweeks. Changes in CF status were analyzed descriptively, while intervention effects were analyzed with split plot ANOVA. The cost of the WE-RISE™ intervention was calculated using activity-based costing.Results: Within the experimental group, 74.1% and 63% of the participants were no longer cognitively frail at the 12thand 24thweeks, respectively, and significant intervention effects were observed for cognition, physical function, body composition, disability, health-related quality of life and self-perceived exercise self-efficacy (p<0.05) following participation in WE-RISE™. The cost per intervention session was RM4.06 (≈USD0.90), and the cost per subject for 48 sessions was RM194.74 (≈USD43.39).Conclusion: The WE-RISE™ multidomain intervention may have the potential to address the reversible nature of CF, is of low cost, and can contribute significantly to the overall well-being of older adults while ensuring equitable access to healthcare. Trial registration: This trial was registered in the Australian New Zealand Clinical Trials Registry (ACTRN12619001055190) on the 29th of July 2019 – retrospectively registered.
FRW universe in f (G, T ) gravity with time dependent deceleration parameter
Authors: Tiwari Rishi Kumar , Shukla Bhupendra Kumar 
Published: July 2023

Abstract
In this study, we explore specific categories of f (G, T) gravity, which hold promise in terms of their ability to explain phenomena such as dark energy and the inflationary epoch. Our aim is to examine the general formalism and illustrate how various evolutions related to inflation and dark energy can be accounted for within the framework of f (G, T) gravity. We propose a unified model where f (G, T) gravity governs both early and late-time dynamics, leading to inflation and the dark energy phase, while resembling ordinary Einstein-Hilbert gravity during an intermediate era. The specific expression we consider for the f (G, T) theory is f (G, T) = G + mG 2 + nT , where m and n are free parameters. To solve the field equation, we utilize a specialized formulation of the deceleration parameter, represented as q = α + βH, where α and β being model parameters. We then determine the optimal values for these model parameters by fitting them to the latest observational datasets, including 57 data points from the Cosmic Chronometers datasets, Pantheon datasets, and BAO datasets.Furthermore, we analyze the physical behavior of cosmographic parameters corresponding to the constrained values of the model parameters, as well as the energy density and pressure. The evolution of the deceleration parameter predicts a transition from a decelerated phase to an accelerated phase of the Universe. Remarkably, our f (G, T) cosmological model effectively describes the observed cosmic acceleration in the late-time universe, thereby eliminating the need to introduce a dark energy component in the field equations.
A case of human diarrhea caused by Gallibacterium anatis: a case report
Authors: Wang Huixuan , Wu Fei , Han Haixia , Zhao Jianhua , Mao Liping 
Published: July 2023

Abstract
Background
Gallibacterium anatis (G. anatis) is a gram-negative bacterium of the Pasteurellaceae family that resides normally in the reproductive and respiratory tracts in poultry. It is an opportunistic pathogen previously associated with deaths in poultry and is also a pathogen that rarely causes human diseases. G. anatis has only been reported twice in France as the causative agent of a human disease. Here, we report a case of diarrhea caused by this bacterium in a patient with hypertension and type 2 diabetes.
Case presentation
We reported a 62-year-old male patient with hypertension and type 2 diabetes who suffered from acute watery diarrhea 7–8 times per day caused by G. anatis. He took belladonna sulfamethoxazole and trimerhoprim tablets for 3 days by himself without the guidance of a doctor. However, there was no improvement. One day after receiving ciprofloxacin lactate combined with clindamycin as antimicrobial treatment in the community hospital, there was no significant improvement. After admission to the EICU in our hospital, the stool culture was positive for G. anatis, which was identified by MALDI-TOF MS and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, amoxicillin and clavulanate potassium were administered as antimicrobial agents, and methylprednisolone sodium succinate was administered as an anti-inflammatory agent. The patient was cured and discharged after 8 days of treatment.
Conclusion
This case shows that clinicians should consider that G. anatis may be a possible infectious source of human diarrhea in immunosuppressive populations.
The Effects of Thermal Modification on the Properties of Zeolitic Imidazolate Framework-8 (ZIF-8) Catalysts in Transesterification
Authors: Yu Ting , Dubas Stephan Thierry , Kitiyanan Boonyarach 
Published: July 2023

Abstract
A simple and effective thermal method for modifying Zeolitic Imidazolate Framework-8 (ZIF-8) was introduced to enhance their catalytic activity toward the triglyceride transesterification. The modified ZIF-8 catalysts were characterized for their change in crystallinity and structure using X-ray diffraction (XRD) along with simultaneous thermal analysis (STA), nitrogen adsorption and desorption analysis, field emission scanning electron microscope (FE-SEM). X-ray photoelectron spectroscopy (XPS) was also used to investigate relevant chemical and physical changes that occur after thermal treatment both in air and nitrogen. Results showed that significant improvements in the catalytic activity and stability of the modified ZIF-8 were observed toward the targeted in transesterification. Interestingly, it was found that the catalysts could be used for at least 5 reactions and that the leaching of Zn2+ from modified ZIF-8 during transesterification reaction was negligible when compared to ZIF-8. This study provides a promising approach to enhance the catalytic performance of ZIF-8 by mean of oxidation and provided significant improvement when applied to the transesterification of triglyceride.
Effect of L-Lysine on heat-induced aggregation behavior of Antarctic krill (Euphausia superba) myofibrillar protein
Authors: Lin Junxin , Sun Peizi , Zhao Yanfen , Du Xiaoping , Ren Xiang , Man Hao , Li Dongmei 
Published: July 2023

Abstract

Heat treatment reduces the quality of Antarctic krill (Euphausia superba), thus greatly limiting its industrial application. Although L-Lys immersion pretreatment can effectively improve the quality of heat-treated Antarctic krill meat, the underlying mechanism is unclear. This study aimed to investigate the effect of different L-Lys concentrations (0, 25, 50, 100, and 200 mM) on the aggregation behavior and structure of Antarctic krill myofibrillar protein solution before and after heat treatment. Compared with the untreated group, L-Lys decreased the surface hydrophobicity and particle size of the heat-treated Antarctic krill protein by 2.38 times and 18.27 times while increasing the solubility by 3.59 times. Furthermore, L-Lys intervention inhibited the formation of disulfide bonds in myofibrillar protein of the heat-treated Antarctic krill, enhanced the intermolecular hydrogen bonding force, improved the orderliness of the secondary structure, and "exposed" the tyrosine residues of the protein molecule. As a result, the polarity of the microenvironment was enhanced while the tertiary structure of the protein was altered, thus inhibiting thermal aggregation behavior and improving the water-holding capacity and tenderness of heat-treated Antarctic krill. This study reveals the mechanism of L-Lys inhibition of thermal aggregation behavior of Antarctic krill myofibrillar protein. Our results provide insights into the development and utilization of Antarctic krill protein in the food industry.
Moderate hypofractionated radiotherapy to the pelvis and/or prostate bed after prostatectomy: a prospective trial
Authors: Canales Juan P. , Barnafi Esteban , Salazar Cristian , Reyes Paula , Merino Tomas , Calderón David , Cortés Analía 
Published: July 2023

Abstract
Background Hypofractionated radiotherapy in the treatment of prostate cancer has been widely studied. However, in the postoperative setting it has been less explored. The objective of this prospective study is to evaluate the safety and efficacy of hypofractionated radiotherapy in postoperative prostate cancer.
Methods A prospective study was designed that recruited patients with prostate cancer with an indication of postoperative radiotherapy as adjuvant or salvage. A hypofractionated radiotherapy scheme of 51 Gy in 17 fractions was performed with the possibility of treating the pelvis at a dose of 36 Gy in 12 fractions sequentially. Safety was evaluated based on acute and late toxicity (according to the RTOG scale and CTCAE v4.03), IPSS over time, and quality of life.
Results From August 2020 to June 2022, 31 patients completed treatment and are included in this report. 35.5% of patients received elective treatment of pelvic nodal areas. Most patients report minimal or low acute toxicity, with an acute GI and GU grade 3 or greater toxicity of 3.2% and 0%, respectively. The evolution in time of the IPSS remained without significant differences (p 0.42). With the exception of a significant improvement in the domains of hormonal and sexual symptoms of the EPIC questionnaire, the rest of the domains EPIC, EORTC-C30 and PR-25 were maintained without significant differences over time. With a follow-up of 15.4 months, late GI and GU grade 2 toxicity was reported greater than 0% and 9.6%, respectively.
Conclusions Hypofractionated radiotherapy in postoperative prostate cancer appears to be safe. Low report of relevant acute or late toxicity. Further follow-up is required to confirm these results. Trial registration The protocol was approved by the accredited Medical Ethical Committee of Pontificia Universidad Católica de Chile. All participants accepted and wrote informed consent
Collaborative multi-objective port allocation scheduling considering carbon emissions
Authors: Liu Yuhao , Yang Zhiying 
Published: July 2023

Abstract
In previous port studies, most researchers have only considered individual optimisation and very few studies have reduced carbon emissions. To solve this problem, this paper considers carbon emissions, maximum completion time and minimisation of the distance from the berthing location to its corresponding yard area for the entire period in a unified manner for the automated terminal as a whole while considering berth allocation, bridge crane allocation and yard allocation simultaneously. For solving this multi-objective non-linear mixed integer programming model, an improved Harris Hawk Optimisation algorithm (HHO) is used to solve the model and compared with improved genetic algorithms and particle swarm algorithms, along with sensitivity analysis. The experimental results show that the improved HHO algorithm is able to find a better solution in a smaller number of iterations and in a shorter total time compared to the traditional algorithm. The sensitivity analysis also shows that increasing the length of the shoreline with the same number of ships not only reduces the total cost but also increases the speed of solving the model, unless the number of quay cranes is extremely tight, which is generally not recommended to increase their number.
The Interplay of Socioeconomic Status, Gender, and Age in Determining Physical Activity: Evidence from the China Family Panel Studies
Authors: Jiao Kaishan , Zhang Jiujuan , Liu Meng , Xu Mengjia 
Published: July 2023

Abstract
Background
Physical activity plays an integral role in promoting health and well-being. Despite its importance, comprehensive studies exploring the influences of socio-demographic factors on physical activity in the Chinese context are relatively scarce. This study aims to investigate the relationship between physical activity and socio-demographic factors such as gender, age, and socioeconomic status, using data from the 2018 China Family Panel Studies (CFPS).
Methods
Data was derived from the 2018 CFPS, resulting in a final sample size of 21,854 adults, with physical activity as the dependent variable. The International Socio-Economic Index of Occupational Status (ISEI) was used to gauge socioeconomic status. Other incorporated variables included gender, age, community type, marital status, physical health, and mental health. The study employed a logistic regression model considering the dichotomous nature of the dependent variable.
Results
Significant correlations were found between physical activity and gender, age, and socioeconomic status. Men were found to be more likely to engage in physical activity than women, and the likelihood of physical activity increased with age and socioeconomic status. Further, the influence of socioeconomic status on physical activity was found to vary significantly across different genders and age groups, with complex intersections noted among these factors.
Conclusion
The study underscores the need for public health interventions that are mindful of the complex interplay between gender, age, and socioeconomic status in influencing physical activity. Efforts to promote physical activity should focus on bridging the disparities arising from these socio-demographic factors, especially targeting women and individuals from lower socioeconomic classes. Future research should delve into the mechanisms through which these factors intersect and explore other potential influential elements to enhance our understanding of physical activity behavior.
Using Resistivity Gradient Method to Monitor Surface Water Movements
Authors: El-Kholy Rowan , Hassan Heba , Aziz Akram M 
Published: July 2023

Abstract
Near-surface geophysics investigations encompass a diverse range of application areas that are supported by both basic and applied research. These application areas are characterized by various descriptors, such as engineering, geotechnical, environmental, groundwater, mining, archaeological, and forensic. The aim of our project is to examine the applicability of small scale arrays to measure the changes in soil due to the movements of surface water. The idea was based in simulating the field conditions inside a lab using regular instruments to measure the volte and currents and calculate the apparent resistivity. These measurements could provide a future cheap tool that can be used in various near-surface geophysical applications.
Food consumption behavior and lifestyle changes among rural older adults before and during the Covid-19 pandemic in Northern India: A cross-sectional study
Authors: Verma Ashish Kumar , Annapurna  , Panchgaur Richa , Kumar Alok 
Published: July 2023

Abstract
Background: Due to Covid-19, the lockdown was imposed throughout the nation on 24 march 2020 and Covid-19 is not over yet, cases are still coming. Food insecurity was already a problem but it became even more challenging during the pandemic. Especially rural older adult people have had to deal with the problem of food and health-related issues due to the pandemic.
Objective: This study aimed to assess food consumption behavior and lifestyle changes among rural older adults before and during the Covid-19 pandemic.
Material and Methods: A retrospective cross-sectional study has been done; a multistage random sampling technique was used to select the participants. 450 participants were taken aged 60 and above for final analysis. The survey was conducted in the rural areas of the Varanasi District, Uttar Pradesh through personal interviews. The McNemar and Wilcoxon sign rank tests were used to examine differences before and during the Covid-19 pandemic, adopting the statistical significance of p< 0·05.
Results: Mean age of participants were found 66.72 years. 66.0% of people faced a shortage of food. 40.9% of people reported that they had reduced their food intake and 39.6% reported that the reduction in food intake was due to the rise in the price of edible items. 27.6% of participants reported a reduction in body weight. There was a significant percentage decrease in consumption of milk products, pulse, and green vegetables(p<0.001), a percentage decrease in initiating and maintaining sleep (p<0.001), and worse health conditions (p<0.001).
Conclusions: Food consumption behavior and lifestyles have changed significantly during the Covid-19 pandemic among rural older adults. Although some lifestyles haven’t changed significantly, the quantity of food and health conditions were compromised.