bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stakeholder evaluation of sustainability in a community-led wastewater treatment facility in Jakarta, Indonesia
Authors: Cecilia Shandy , Murayama Takehiko , Nishikizawa Shigeo , Suwanteep Kultip 
Published: March 2023

AbstractIndonesia’s severely flawed centralized wastewater treatment system has caused economic and socioeconomic losses for decades. An alternative system has been called for under a national-scale program called Sanimas or Community-Led Total Sanitation (CLTS), which would cater to 50–100 urban families in every intervention with urgent needs through the operation of a decentralized wastewater treatment system. Through household participation, this program features a co-production system wherein the national-level government initiates and provides initial funding until construction, after which a community-appointed social organization takes over. This study implemented a multicriteria approach to assess sustainability in Sanimas communities in Jakarta: 67 in Menteng (Central Jakarta) and At-Taubah in Koja (North Jakarta). Connected households and facility-operating committees were questioned separately for their opinions on six aspects that explained the survival of the establishment of a facility: technical, management, community participation, financial, institutional, and environmental. We found that although the facility’s excellence and overall satisfaction with the program were unanimous, Koja and Menteng showed substantial differences in management, institutional, and financial aspects, largely due to administrative policies, payment contributions, and committee commitments. Interviews revealed that periodic testing of the treated water was neglected, against the provided guidance. In conclusion, communities have come to focus more on the technical functionalities of the installation, regardless of the state of the management, which is indisputable not only in Menteng but also in Koja. Finally, we argue that although decentralized systems can substitute centralized systems, they still require stringent and adequate support in quality control and troubleshooting.
A Novel Design Eco-friendly Microwave-assisted Cu–N@CQDs Sensor for the Quantification of Eravacycline via Spectrofluorimetric Method; Application to Greenness Assessments, Dosage Form and Biological Samples
Authors: Salman Baher I. 
Published: March 2023

AbstractCommunity-acquired pneumonia is one of the most common infectious diseases and a substantial cause of mortality and morbidity worldwide. Therefore eravacycline (ERV) was approved by the FDA in 2018 for the treatment of acute bacterial skin infections, GIT infections, and community-acquired bacterial pneumonia caused by susceptible bacteria. Hence, a green highly sensitive, cost-effective, fast, and selective fluorimetric approach was developed for the estimation of ERV in milk, dosage form, content uniformity, and human plasma. The selective method is based on the utilization of plum juice and copper sulphate for the synthesis of green copper and nitrogen carbon dots (Cu–N@CDs) with high quantum yield. The quantum dots' fluorescence was enhanced after the addition of ERV. The calibration range was found to be in the range 1.0 – 80.0 ng mL−1 with LOQ equal to 0.14 ng mL−1 and LOD was found to be 0.05 ng mL−1. The creative method is simple to deploy in clinical labs and therapeutic drug health monitoring system. The current approach has been bioanalytically validated using US-FDA and validated ICH criteria. High-resolution transmission electron microscopy (HR-TEM), X-ray photon spectroscopy (XPS), Zeta potential measurements, fluorescence, UV–VIS, and FTIR spectroscopy have all been used to fully characterize the Cu–N@CQDs. The Cu–N@CQDs were effectively applied in human plasma and milk samples with a high percentage of recovery ranging from 97.00 to 98.80%.
Co-Delivery of D-LAK Antimicrobial Peptide and Capreomycin as Inhaled Powder Formulation to Combat Drug-Resistant Tuberculosis
Authors: Shao Zitong , Chow Michael Y. T. , Chow Shing Fung , Lam Jenny K. W. 
Published: March 2023

Abstract
Introduction
The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) posed a severe challenge to tuberculosis (TB) management. The treatment of MDR-TB involves second-line anti-TB agents, most of which are injectable and highly toxic. Previous metabolomics study of the Mtb membrane revealed that two antimicrobial peptides, D-LAK120-A and D-LAK120-HP13, can potentiate the efficacy of capreomycin against mycobacteria.

Aims
As both capreomycin and peptides are not orally available, this study aimed to formulate combined formulations of capreomycin and D-LAK peptides as inhalable dry powder by spray drying.

Methods and Results
A total of 16 formulations were prepared with different levels of drug content and capreomycin to peptide ratios. A good production yield of over 60% (w/w) was achieved in most formulations. The co-spray dried particles exhibited spherical shape with a smooth surface and contained low residual moisture of below 2%. Both capreomycin and D-LAK peptides were enriched at the surface of the particles. The aerosol performance of the formulations was evaluated with Next Generation Impactor (NGI) coupled with Breezhaler®. While no significant difference was observed in terms of emitted fraction (EF) and fine particle fraction (FPF) among the different formulations, lowering the flow rate from 90 L/min to 60 L/min could reduce the impaction at the throat and improve the FPF to over 50%.

Conclusions
Overall, this study showed the feasibility of producing co-spray dried formulation of capreomycin and antimicrobial peptides for pulmonary delivery. Future study on their antibacterial effect is warranted.
Three-Dimensional Reconstruction of Coronal Features: A Python Tool for Geometric Triangulation
Authors: Nisticò Giuseppe 
Published: March 2023

AbstractThe determination of the three-dimensional (3D) geometry of coronal features is important for understanding the magnetic structuring of the solar atmosphere. In this context, the length of a coronal loop, which is subject to standing transverse oscillations, is a crucial parameter in coronal seismology for the correct estimation of the phase speed of the wave and, consequently, of the Alfvén speed and coronal magnetic-field strength. Simultaneous space-based observations of the solar corona from different vantage points, e.g. one from the Solar Dynamics Observatory (SDO) and the second from the Solar TErrestrial RElations Observatory (STEREO), have permitted the reconstruction of the geometry of coronal loops. Nisticò, Verwichte, and Nakariakov (Entropy15, 4520, 2013) proposed a method based on principal component analysis for fitting an ensemble of 3D points that sample a coronal loop. This method was shown to retrieve easily the main geometric parameters that define a loop, such as the loop axes and the loop plane. In this article, an extension of that work is presented that includes a Python tool for performing geometric triangulation of coronal features seen by two different observers.
MECInOT: a multi-access edge computing and industrial internet of things emulator for the modelling and study of cybersecurity threats
Authors: Ruiz-Villafranca Sergio , Carrillo-Mondéjar Javier , Castelo Gómez Juan Manuel , Roldán-Gómez José 
Published: March 2023

AbstractIn recent years, the Industrial Internet of Things (IIoT) has grown rapidly, a fact that has led to an increase in the number of cyberattacks that target this environment and the technologies that it brings together. Unfortunately, when it comes to using tools for stopping such attacks, it can be noticed that there are inherent weaknesses in this paradigm, such as limitations in computational capacity, memory and network bandwidth. Under these circumstances, the solutions used until now in conventional scenarios cannot be directly adopted by the IIoT, and so it is necessary to develop and design new ones that can effectively tackle this problem. Furthermore, these new solutions must be tested in order to verify their performance and viability, which requires testing architectures that are compatible with newly introduced IIoT topologies. With the aim of addressing these issues, this work proposes MECInOT, which is an architecture based on openLEON and capable of generating test scenarios for the IIoT environment. The performance of this architecture is validated by creating an intelligent threat detector based on tree-based algorithms, such as decision tree, random forest and other machine learning techniques. Which allows us to generate an intelligent and to demonstrate, we could generate an intelligent threat detector and demonstrate the suitability of our architecture for testing solutions in IIoT environments. In addition, by using MECInOT, we compare the performance of the different machine learning algorithms in an IIoT network. Firstly, we present the benefits of our proposal, and secondly, we describe the emulation of an IIoT environment while ensuring the repeatability of the experiments.
Leakage Threshold of a Saddle Point
Authors: Huang De , Yan Xiang , Larsson Roland , Almqvist Andreas 
Published: March 2023

AbstractThe threshold condition for leakage inception is of great interest to many engineering applications, and it is essential for seal design. In the current study, the leakage threshold is studied by means of a numerical method for a mechanical contact problem between an elastic bi-sinusoidal surface and a rigid flat surface. The coalesce process of the contact patches is first investigated, and a generalized form of solution for the relation between the contact area ratio and the average applied pressure is acquired. The current study shows that the critical value of the average applied pressure and the corresponding contact area required to close the percolation path can be represented as a power law of a shape parameter, if the effect of the hydrostatic load from the pressurized fluid is ignored. With contact patches merged under a constant applied load, the contact breakup process is investigated with elevated sealed fluid pressure condition, and it is shown that the leakage threshold is a function of the excess pressure, which is defined as a ratio between the average applied pressure and the critical pressure under dry contact conditions.
Graphical abstract
Critical Closing Pressure and Cerebrovascular Resistance Responses to Intracranial Pressure Variations in Neurocritical Patients
Authors: Brasil Sérgio , de Carvalho Nogueira Ricardo , Salinet Ângela Salomão Macedo , Yoshikawa Márcia Harumy , Teixeira Manoel Jacobsen , Paiva Wellingson , Malbouisson Luiz Marcelo Sá , Bor-Seng-Shu Edson , Panerai Ronney B. 
Published: March 2023

Abstract
Background
Critical closing pressure (CrCP) and resistance-area product (RAP) have been conceived as compasses to optimize cerebral perfusion pressure (CPP) and monitor cerebrovascular resistance, respectively. However, for patients with acute brain injury (ABI), the impact of intracranial pressure (ICP) variability on these variables is poorly understood. The present study evaluates the effects of a controlled ICP variation on CrCP and RAP among patients with ABI.

Methods
Consecutive neurocritical patients with ICP monitoring were included along with transcranial Doppler and invasive arterial blood pressure monitoring. Internal jugular veins compression was performed for 60 s for the elevation of intracranial blood volume and ICP. Patients were separated in groups according to previous intracranial hypertension severity, with either no skull opening (Sk1), neurosurgical mass lesions evacuation, or decompressive craniectomy (DC) (patients with DC [Sk3]).

Results
Among 98 included patients, the correlation between change (Δ) in ICP and the corresponding ΔCrCP was strong (group Sk1 r = 0.643 [p = 0.0007], group with neurosurgical mass lesions evacuation r = 0.732 [p < 0.0001], and group Sk3 r = 0.580 [p = 0.003], respectively). Patients from group Sk3 presented a significantly higher ΔRAP (p = 0.005); however, for this group, a higher response in mean arterial pressure (change in mean arterial pressure p = 0.034) was observed. Exclusively, group Sk1 disclosed reduction in ICP before internal jugular veins compression withholding.

Conclusions
This study elucidates that CrCP reliably changes in accordance with ICP, being useful to indicate ideal CPP in neurocritical settings. In the early days after DC, cerebrovascular resistance seems to remain elevated, despite exacerbated arterial blood pressure responses in efforts to maintain CPP stable. Patients with ABI with no need of surgical procedures appear to remain with more effective ICP compensatory mechanisms when compared with those who underwent neurosurgical interventions.
The Making of Gendered Bodies in Human-Robot Interactions
Authors: Velázquez Isabel García 
Published: March 2023

AbstractWith a growing curiosity in anthropomorphic robots, academics and interested parties have started to examine the ethical implications and social impacts of their (mis)use. Gender in anthropomorphic robots is a field that is slowly beginning to receive attention. Yet, its ambiguity has led to treating gender in anthropomorphic robots in a reductionist fashion, pointing to how stereotypical characteristics make certain gender identities and practices legible. I illustrate that the making of gendered bodies goes beyond the oversimplification of stereotypical readable gender cues. Thus, relational and corporeal ways of connecting people and technological artifacts can help to (de)construct the practices of gendering the human body and the body of anthropomorphic robots. This entails ‘alive genders’. By ‘alive genders’ I am referring to an approach which keeps understandings of gender destabilized and evolving. This not only brings awareness to the interdependence of the human body and the body of anthropomorphic robots but helps designers and roboticists to study the gendering of robots as a part of social practices.
Population differences in completeness and reliability of Dutch COVID-19 registry data
Authors: van Deursen Babette , de Jonge Ester A. L. 
Published: March 2023

AbstractDuring the COVID-19 pandemic, the bidirectional relationship between policy and data reliability has been a challenge for researchers of the local municipal health services. Policy decisions on population specific test locations and selective registration of negative test results led to population differences in data quality. This hampered the calculation of reliable population specific infection rates needed to develop proper data driven public health policy.
Mehrsprachigkeit, digitale Praxis und Schreibfähigkeit
Authors: Usanova Irina , Schnoor Birger , Gogolin Ingrid 
Published: March 2023

ZusammenfassungDurch die fortschreitende Digitalisierung der Lebenswelt finden auch die literalen Praktiken des Lesens und Schreibens vermehrt in digitaler Modalität statt. Ziel der vorliegenden Studie ist es, Erkenntnisse darüber zu liefern, (1) ob lebensweltlich mehrsprachige Jugendliche bei digitalen Praktiken von ihrer Mehrsprachigkeit Gebrauch machen und (2) in welchem Verhältnis ihre digitalen Praktiken zu ihrer mehrsprachigen Schreibfähigkeit stehen. Analysiert wurden Fragebogendaten zur Nutzung digitaler Medien und Testdaten zur multilingualen Schreibfähigkeit aus der Studie „Mehrsprachigkeit an der Schwelle zum Beruf (MEZ-2)“. Die Ergebnisse der vorliegenden Studie zeigen, dass die untersuchten Jugendlichen (n = 277) in erheblichem Maß Gebrauch von mehrsprachigen Fähigkeiten in ihrer digitalen Lebenswelt machen. In der untersuchten Population konnten vier Typen mehrsprachiger digitaler Literalitätspraktiken unterschieden werden. Die Typen unterscheiden sich sowohl nach der Anzahl genutzter Sprachen beim digitalen Lesen und Schreiben (monolingual, zweisprachig oder mehrsprachig) als auch bezüglich der Häufigkeit der literalen Praxen. In Bezug auf das Verhältnis zwischen digitalen literalen Praktiken und multilingualer Schreibfähigkeit konnte, sprachübergreifend, kein systematischer Zusammenhang feststellt werden.
Interventions to Modify Psychological Well-Being: Progress, Promises, and an Agenda for Future Research
Authors: Kubzansky Laura D. , Kim Eric S. , Boehm Julia K. , Davidson Richard J. , Huffman Jeffrey C. , Loucks Eric B. , Lyubomirsky Sonja , Picard Rosalind W. , Schueller Stephen M. , Trudel-Fitzgerald Claudia , VanderWeele Tyler J. , Warran Katey , Yeager David S. , Yeh Charlotte S. , Moskowitz Judith T. 
Published: March 2023

Abstract
Psychological well-being, characterized by feelings, cognitions, and strategies that are associated with positive functioning (including hedonic and eudaimonic well-being), has been linked with better physical health and greater longevity. Importantly, psychological well-being can be strengthened with interventions, providing a strategy for improving population health. But are the effects of well-being interventions meaningful, durable, and scalable enough to improve health at a population-level? To assess this possibility, a cross-disciplinary group of scholars convened to review current knowledge and develop a research agenda. Here we summarize and build on the key insights from this convening, which were: (1) existing interventions should continue to be adapted to achieve a large-enough effect to result in downstream improvements in psychological functioning and health, (2) research should determine the durability of interventions needed to drive population-level and lasting changes, (3) a shift from individual-level care and treatment to a public-health model of population-level prevention is needed and will require new infrastructure that can deliver interventions at scale, (4) interventions should be accessible and effective in racially, ethnically, and geographically diverse samples. A discussion examining the key future research questions follows.
Electronic structural and lattice thermodynamic properties of MAlO2 and M5AlO4 (M = Li, Na, K) sorbents for CO2 capture applications
Authors: Duan Yuhua 
Published: March 2023

AbstractThe electronic properties and thermal stabilities of MAlO2 and M5AlO4 (M = Li, Na, K) are investigated by density functional theory and lattice phonon dynamics. Based on the calculated electronic and lattice thermodynamic properties, their abilities to capture CO2 as solid sorbents are analyzed. The calculated electronic structural properties of MAlO2 and M5AlO4 indicate that all these alkali aluminates are semiconductors with a bandgap range of 2.4 ~ 6.4 eV. The 1st valence bands of these alkali aluminates are located 0 ~ − 6 eV under Fermi levels and are mainly contributed by p orbitals of O, s and p orbitals of Al and M. The phonon vibrational frequencies of M5AlO4 spread at a lower frequency range compared to their MAlO2 phases. With increasing temperature, the calculated phonon free energies of M5AlO4 decrease faster than their corresponding MAlO2 while their entropies have opposite trends. The reaction 2MAlO2 + CO2 = M2CO3 + Al2O3 has higher reaction heat and Gibbs free energy change than those of corresponding reaction 2/5M5AlO4 + CO2 = M2CO3 + 1/5Al2O3, which shows the former reaction possesses lower turnover temperature. Among the alkali aluminates studied, the β-NaAlO2, lt-KAlO2, and γ-LiAlO2 are better candidates that could be applied for CO2 capture technologies.
Graphical Abstract
All for One, and One for All? Analysing Party Positions on EU Solidarity in Germany in Challenging Times
Authors: Reinl Ann-Kathrin , Wallaschek Stefan 
Published: March 2023

AbstractThis article analyses party positions on European Union (EU) solidarity in Germany in the run-up to the 2021 German federal elections. While previous studies have investigated whether and under which conditions individuals support or reject different types of EU solidarity, little is known about how political parties position themselves on the issue. The study draws on an original expert survey on German party positions, including various items on EU solidarity. First, we demonstrate that the GAL–TAN dimension strongly shapes party positionings on EU solidarity. Second, the support by political parties varies along the long- or short-term institutionalization of types of EU solidarity. Third, the findings have political implications for the current German government coalition, revealing potential problems for a joint political agenda on EU affairs.
Buckling of laminated composite plates and shell panels with some free edges under compression and shear
Authors: Prabhakara M. K. 
Published: March 2023

SummaryA general analytical solution for the buckling of laminated composite plates and shell panels for all combinations of free, simply supported and clamped edge conditions is presented. The solution is formulated in terms of stress function and transverse deflection. All the boundary conditions for the stress function are exactly satisfied. For the transverse deflection the prescribed boundary conditions are satisfied by including them in the expression for the energy integral. Several types of boundary conditions in which at least a pair of opposite edges of the panel are free and subjected to axial compression are considered. The Galerkin method, with beam vibration functions used as shape functions, is utilised to determine the buckling loads. The results obtained are used to examine the effect of bending-extensional coupling, aspect ratio and the curvature parameter on the buckling load.