bluuebunny/crossref_metadata_2025_split huggingface dataset:
Losing the light at the end of the tunnel: Depression, future thinking, and hope
Authors: Vazard Juliette 
Published: May 2023

Is the capacity to experience hope central to our ability to entertain desirable future possibilities in thought? The ability to project oneself forward in time, or to entertain vivid positive episodic future thoughts, is impaired in patients with clinical depression. In this article, I consider the causal relation between, on the one hand, the loss of the affective experience of hope in depressed patients, and on the other hand, the reduced ability to generate and entertain positive episodic future thinking. I suggest that findings in the philosophy of emotion may shed light on this causal relation.
A novel effector RipBT contributes to Ralstonia solanacearum virulence on potato
Authors: Qiu Huishan , Wang Bingsen , Huang Mengshu , Sun Xiaohu , Yu Liu , Cheng Dong , He Wenfeng , Zhou Dan , Wu Xintong , Song Botao , Tang Ning , Chen Huilan 
Published: May 2023

AbstractRalstonia solanacearum is one of the most destructive plant‐pathogenic bacteria, infecting more than 200 plant species, including potato (Solanum tuberosum) and many other solanaceous crops. R. solanacearum has numerous pathogenicity factors, and type III effectors secreted through type III secretion system (T3SS) are key factors to counteract host immunity. Here, we show that RipBT is a novel T3SS‐secreted effector by using a cyaA reporter system. Transient expression of RipBT in Nicotiania benthamiana induced strong cell death in a plasma membrane‐localization dependent manner. Notably, mutation of RipBT in R. solanacearum showed attenuated virulence on potato, while RipBT transgenic potato plants exhibited enhanced susceptibility to R. solanacearum. Interestingly, transcriptomic analyses suggest that RipBT may interfere with plant reactive oxygen species (ROS) metabolism during the R. solanacearum infection of potato roots. In addition, the expression of RipBT remarkably suppressed the flg22‐induced pathogen‐associated molecular pattern‐triggered immunity responses, such as the ROS burst. Taken together, RipBT acts as a T3SS effector, promoting R. solanacearum infection on potato and presumably disturbing ROS homeostasis.
Autopsies on the body of nature: Dark ecology in Thomas Bernhard'sVerstörung
Authors: Franch Bastian Ljung 
Published: May 2023

AbstractVerstörung—often considered a minor work by Bernhard—is a somewhat overlooked example of ecologically oriented fiction in the German language. In this novel, Bernhard examines the implications of a darkly ecological concept of the environment (as this article characterizes it with reference to Timothy Morton), confronting it with epistemological questions and placing it in the context of psychoanalysis and Schopenhauerian metaphysics. The novel anticipates some important aspects of the Anthropocene thesis in its critique of the nature/culture divide, its widening of the concept of agency, its insistence on viewing individual human history in the context of natural history, its problematization of the natural/synthetic distinction and its consistent utilization of geological imagery.Verstörungis suffused with a remarkable, dark, and twisted proto‐Anthropocene aesthetics. It is a post‐mortem examination of the worldafter nature, aGefühls‐ und Gesteinsgeschichtethat carries the reader into the dark heart of the Austrian countryside.
From the Destruction of Two Lumbar Segments to Thoracic‐Lumbar‐Pelvic Fusion: A Case Caused by Congenital Insensitivity to Pain with Anhidrosis and Literature Review
Authors: Jiao Yuhao , Tian Ye , Cai Siyi 
Published: May 2023

BackgroundCongenital insensitivity to pain with anhidrosis (CIPA) with Charcot arthropathy is a rare combination in orthopaedic clinical practice. The experience dealing with such patients is limited. Here with this case of approximately 10 years follow‐up, we wish to shed light on the choices of strategies of surgeries and alerting clinicians with post‐surgery complications. The possible underlying reasons for the recurrent Charcot arthropathies as well as strategies for peri‐operative management for such surgical cases are also discussed.Case PresentationThe patient underwent a surgery to correct her severe kyphosis caused by CIPA‐related Charcot spine. Multiple post‐surgery complications occurred during her follow‐up, including hardware migration, adjacent segment disease (ASD), and loosening pedicle screws. Five revision surgeries were conducted consequently. From the limited experience on the management of CIPA‐related Charcot spine, surgical correction is still the first‐line treatment.ConclusionsOf all the 16 cases reviewed (including our case), loosening pedicle screws, hardware migration, and ASDs are the common post‐surgery complications. Large‐scale removal of damaged vertebrae and subsequent reconstruction are not recommended, which might increase the risk of hardware migration. A 360° long‐segment fusion might be of help to reduce the risk of ASDs. In the meantime, comprehensive management including careful nursing, proper rehabilitation exercises, and treatments targeting bone mineral metabolism is also critical.
Three‐dimensional structural analysis of papillary thyroid carcinoma nuclei with serial block‐face scanning electron microscopy (SBF‐SEM)
Authors: Inoue Tomohiro , Ohno Nobuhiko , Oishi Naoki , Mochizuki Kunio , Katoh Ryohei , Kondo Tetsuo 
Published: May 2023

AbstractNuclear morphology of carcinoma cells is critical for the pathological diagnosis of papillary thyroid carcinoma (PTC). However, three‐dimensional architecture of PTC nuclei is still elusive. In this study, we analyzed the three‐dimensional ultrastructure of PTC nuclei using serial block‐face scanning electron microscopy which takes advantage of the high‐throughput acquisition of serial electron microscopic images and three‐dimensional reconstruction of subcellular structures. En bloc‐stained and resin‐embedded specimens were prepared from surgically removed PTCs and normal thyroid tissues. We acquired two‐dimensional images from serial block‐face scanning electron microscopy and reconstructed three‐dimensional nuclear structures. Quantitative comparisons showed that the nuclei of carcinoma cells were larger and more complex than those of normal follicular cells. The three‐dimensional reconstruction of carcinoma nuclei divided intranuclear cytoplasmic inclusions into “open intranuclear cytoplasmic inclusions” connecting to cytoplasm outside the nucleus and “closed intranuclear cytoplasmic inclusions” without that connection. Cytoplasm with abundant organelles was observed in open inclusions, but closed inclusions contained fewer organelles with or without degeneration. Granules with a dense core were only observed in closed inclusions. Our observations suggested that open inclusions originate from nuclear invaginations, and disconnection from cytoplasm leads to closed inclusions.
Time of day of leaf wounding determines plant biomass and affects the interplay between growth and defence in Brassica crops
Authors: Francisco M. , Doghri M. , Rodríguez V. M. 
Published: May 2023

Abstract

Recent discoveries pointed out the importance of the mutual correlation between timing of environmental stress and plant fitness. However, the internal reshaping of plant growth under daily stress sensing, and their metabolic coordination remain to be investigated. Thus, we studied the connection between time of day, growth and defence to understand how plant fitness is affected by diurnal stress inputs.

We examined if simulated herbivory (leaf wounding) in the morning, at midday or the evening differentially influence plant defence state vs growth in three crop species of Brassica: broccoli (Brassica oleraceae), turnip greens (B. rapa) and rapeseed (B. napus).

The data revealed that plant's tolerance of wounding stress is diurnally regulated in Brassica crops. Trade‐offs between biomass and investment in glucosinolates (GSL) and phenolics were affected by timing of leaf stress. Negative correlations between biomass and induction of defence compounds were found for plants treeated in the morning and evening. However, the correlations were positive for midday treatment. Interestingly, we revealed a new connection between plant growth and changes in aliphatic GSLs and flavonoids in response to wounding.

These data suggest that metabolic stress‐dependent circadian oscillations in leaf defences could be one mechanism conferring a competitive advantage to plants to anticipate daily environmental variations by synchronizing them with growth. Moreover, this work provides first insights into how secondary metabolites are linked to growth response in a timing‐related manner.
Operationalizing social equity in public policy design: A comparative analysis of solar equity policies in the United States
Authors: Zhou Shan , Gao Xue , Wellstead Adam M. , Kim Dong Min 
Published: May 2023

AbstractWhile it is widely recognized that energy injustices are prevalent in the clean energy transition process, there has been limited research attention on policy efforts aiming to mitigate these inequities. In this paper, we use solar equity policies as an empirical case study to understand how social equity considerations are conceptualized and operationalized in energy policy content. We build upon the policy design literature and code institutional statements of 54 solar equity policies adopted between 2001 and 2021 in the United States. In our comparative analysis, we focus on three levels of policy design elements that can be directly observed in written policy language: macro‐policy goal construction, meso‐policy instrument choices, and micro‐level policy settings and calibrations. We find that the policy goal of energy justice is multifaceted, with a great emphasis on solar energy accessibility and provision of economic benefits and security for disadvantaged communities. There is a dominant preference by policymakers to use redistributive policies and community solar programs to advance energy justice‐related goals. Solar equity policy instruments on‐the‐ground measures have also been calibrated to target specific disadvantaged populations in the energy system, which focus mostly on income‐based vulnerability.
The association between the interaction of migration background and physical activity with loneliness in middle‐aged and older adults living in Germany
Authors: Baumbach Linda , Barth Lena , König Hans‐Helmut , Hajek André 
Published: May 2023

BackgroundReduced physical activity and having a migration background are both associated with higher loneliness; however, the moderating role of migration background in the association between loneliness and physical activity remains largely unknown.MethodsWe used cross‐sectional data from the sixth wave (year 2017) of the German Ageing Survey (DEAS). Loneliness was measured using the De Jong Gierveld tool and physical activity was dichotomised into either of the following (i.e., at least 150 min of moderate physical activity per week) or not following physical activity recommendations of the World Health Organization (WHO). For evaluation of the associations we applied adjusted linear regression models with robust standard errors.ResultsWe included 6257 (average age = 67 years, 50% female) and 285 (average age = 63 years, 51% female) participants without and with migration background, respectively. In multiple linear regressions both migration background (ß = 0.13, P = 0.001), as well as not following the WHO physical activity recommendations (ß = 0.06, P < 0.001) were associated with increased loneliness. Moreover, the respective interaction term reached statistical significance (ß = −0.27, P = 0.013). Participants with migration background have a more pronounced association between following the WHO physical activity recommendations and reduced loneliness compared to participants without migration background.ConclusionAmong middle‐aged and older individuals, those with migration background benefit to a larger extent from following physical activity recommendations than the population without migration background regarding loneliness. Thus, motivating individuals with migration background to follow the WHO physical activity guidelines could particularly assist in reducing loneliness.
Reaction time as a libido indicator and its relation to pre‐freeze and post‐thaw sperm quality in bulls
Authors: Korkmaz Fırat , Baştan İlktan , Şahin Derya , Şimşek Seher , Kaya Ufuk , Satılmış Muharrem 
Published: May 2023

AbstractLibido and sperm quality output relationship is already not clear in farm animals. The present study compared reaction time (RT) as a libido indicator and the pre‐freeze and post‐thaw sperm quality of AI bulls. Before the collection of ejaculates (n = 53, from 22 AI bulls [4.2 ± 1 years of age]), RTs were collected using a chronometer as the interval between the bull's arrival at the semen collection area and his first false mount (FM) on another male. The ejaculates were examined for their volume, concentration and motility. Subsequently, all aliquots were diluted with a commercial semen extender and equilibrated for 3 h before freezing. Frozen semen samples were thawed and examined for sperm kinematics using CASA, plasma membrane and acrosome integrity of sperm (PMAI) by flow cytometry. Additionally, the temperature humidity index (THI) values were assessed during the study. Multiple linear regression analysis was used to analyse the data. The results indicated that THI had a significant effect on libido (p < .001). However, libido had no effect on either pre‐ or post‐thaw sperm quality parameters except for the velocity of the average pathway (VAP) (p < .05). Therefore, relying solely on RT –libido‐ as an indicator of bull sperm quality at AI stations may not be reliable, as it is a complex behavioural assessment.
Orbitally‐driven Palaeogene to Neogene deposition in the western South Atlantic (Espírito Santo Basin) and its correlation with global sea level
Authors: Santos Thiago P. , Lisboa Luana P. , Carreira Victor , Bione Fellippe R. A. , Venancio Igor M. , Bernardes Marcelo C. , Belem Andre L. , Díaz Rut A. , Moreira Manuel , Lopes Alexandre A. O. , Santos Tulio L. , Souza Igor V. , Spigolon André L. D. , Albuquerque Ana Luiza S. 
Published: May 2023

ABSTRACTOver the last 66 million years, Earth has undergone dramatic climate changes, shifting from a warm greenhouse to the more recent cold icehouse with polar ice caps in both hemispheres. Geological records show that the transition between these equilibrium states caused significant long‐term eustatic sea‐level and atmospheric CO2 decline paced by external orbital motions. Such eustatic variability influenced the stacking pattern of sedimentary successions, generating cyclic sequence boundaries that may be globally correlated. However, the impact of such oscillation along the Brazilian margin is largely unknown. This study used the natural gamma‐ray log from a well (ES‐2) at the offshore Espírito Santos Basin (western South Atlantic) measured between late‐Palaeocene and late‐Miocene. Null hypothesis tests ‐ evolutionary Average Spectral Misfit and Correlation Coefficient of no orbital modulation ‐ were executed to confirm the influence of astronomical parameters. The evolutionary Time Optimization algorithm was used to extract the sedimentation rate and depositional time. The anchored timescale shows a chronological interval placed between 58.97 and 7.72 ± 0.1 Ma (mid‐Thanetian – late Tortonian), mostly influenced by long‐eccentricity and short‐eccentricity (405 kyr and ca 100 kyr, respectively) and obliquity (ca 40 kyr) and their respective amplitude modulations (ca 2.4 Myr and 1.2 Myr). Applying the Integrated Prediction Error Filter Analysis and a high‐resolution age model, this study identified main depositional trends through time and correlated them to global sea‐level change. The correlation indicates that several intervals of global sea‐level reduction agree with a regressive trend at the ES‐2 site, but this relation is affected during enhanced regional tectonic activity intervals, as related to the emplacement of the Abrolhos Archipelago. The strategy adopted here is a way to join cyclostratigraphy and sequence stratigraphy, and promotes high‐resolution local‐to‐global correlation by identifying key stratigraphic surfaces. This will be relevant for palaeoclimatic studies and the geoscientific industry.
Pitfalls of amateur regression: The Dutch New Herring controversies
Authors: Gao Fengnan , Gill Richard D. 
Published: May 2023

AbstractApplying simple linear regression models, an economist analyzed a published dataset from an influential annual ranking in 2016 and 2017 of consumer outlets for Dutch New Herring and concluded that the ranking was manipulated. His finding was promoted by his university in national and international media, and this led to public outrage and ensuing discontinuation of the survey. We reconstitute the dataset, correcting errors and exposing features already important in a descriptive analysis of the data. The economist has continued his investigations, and in a follow‐up publication repeats the same accusations. We point out errors in his reasoning and show that alleged evidence for deliberate manipulation of the ranking could easily be an artifact of specification errors. Temporal and spatial factors are both important and complex, and their effects cannot be captured using simple models, given the small sample sizes and many factors determining perceived taste of a food product.
Following residential segregation by race spatiotemporally: A search for causality
Authors: Kim Sung‐Geun 
Published: May 2023

AbstractObjectiveThe study tried to test three existing explanations on residential segregation through spatiotemporal modeling: (1) spatial assimilation, (2) racial prejudice and discrimination, and (3) residential preferences. Since residential segregation is fundamentally a spatial and longitudinal phenomenon, the analysis is expected to provide a fresh perspective on residential segregation.MethodThe study used a spatiotemporal modeling through integrated nested Laplace approximation, which is a Bayesian approach to very complex regression modeling, and the data came from the American Community Survey data from 2005 to 2019 at two different spatial levels—Public Use Microdata Area and census tracts.ResultsThe findings of this study showed that: (1) socioeconomic variables, including income, unemployment, and poverty, have meaningful impacts; (2) housing‐related variables do exert a significant impact on black household concentration; (3) the ratio of Asian and Hispanic populations turns out to be important predictors in a negative direction; and (4) even with the predictors, the non‐trivial temporal and spatiotemporal effects are discovered.ConclusionThe study reveals that a reductionist approach to residential segregation is unlikely to offer meaningful insights into the problem and that proper understanding is possible only when careful consideration of the spatiotemporal context is taken, including the spatial level.
UAV‐based time‐series phenotyping reveals the genetic basis of plant height in upland cotton
Authors: Ye Yulu , Wang Peilin , Zhang Man , Abbas Mubashir , Zhang Jiaxin , Liang Chengzhen , Wang Yuan , Wei Yunxiao , Meng Zhigang , Zhang Rui 
Published: May 2023

SUMMARYPlant height (PH) is an important agronomic trait affecting crop architecture, biomass, resistance to lodging and mechanical harvesting. Elucidating the genetic governance of plant height is crucial because of the global demand for high crop yields. However, during the rapid growth period of plants the PH changes a lot on a daily basis, which makes it difficult to accurately phenotype the trait by hand on a large scale. In this study, an unmanned aerial vehicle (UAV)‐based remote‐sensing phenotyping platform was applied to obtain time‐series PHs of 320 upland cotton accessions in three different field trials. The results showed that the PHs obtained from UAV images were significantly correlated with ground‐based manual measurements, for three trials (R2 = 0.96, 0.95 and 0.96). Two genetic loci on chromosomes A01 and A11 associated with PH were identified by genome‐wide association studies (GWAS). GhUBP15 and GhCUL1 were identified to influence PH in further analysis. We obtained a time series of PH values for three field conditions based on remote sensing with UAV. The key genes identified in this study are of great value for the breeding of ideal plant architecture in cotton.
Outcomes and complications of a modified tibial tuberosity transposition technique in the treatment of medial patellar luxation in dogs
Authors: Cortina Brittany L. , Terreros Alex , Daye R. Mark 
Published: May 2023

AbstractObjectiveTo report a modification of the tibial tuberosity transposition (m‐TTT) technique used to treat medial patellar luxation (MPL) in dogs, and report its complications.Study designRetrospective case series.Sample populationDogs (n = 235) undergoing MPL correction, using m‐TTT (n = 300 stifles).MethodsMedical records and client surveys were reviewed to determine complications associated with this technique and they were compared with previously reported complications using similar techniques.ResultsShort‐term minor complications included low‐grade reluxation (11 stifles, 3.6%), incisional seroma (nine stifles, 3%), pin‐associated swelling (seven stifles, 2.3%), patellar desmitis (six stifles, 2%), superficial incisional infection (four stifles, 1.3%), pin migration (three stifles, 1%), tibial tuberosity (TT) fracture (two stifles, 0.6%), tibial tuberosity displacement and patella alta (one stifle, 0.3%), pin‐associated discomfort (one stifle, 0.3%), trochlear block fracture (one stifle, 0.3%). Short‐term major complications included pin migration (three stifles, 1%), incisional infection (two stifles, 0.6%), tibial tuberosity fracture (two stifles, 0.6%), and high grade reluxation (two stifles, 0.6%). Long‐term follow‐up examination data were available for 109/300 (36.3%) stifles. One minor complication and four major complications were documented. All long‐term complications were due to pin migration. The overall major complication rate was 4.3% (13/300 stifles), with a minor complication rate of 15% (46/300 stifles). The owner survey indicated a 100% satisfaction rate.ConclusionThe m‐TTT technique yielded acceptable complication rates, with high owner satisfaction.Clinical significanceThe m‐TTT should be considered as an alternative technique for treating dogs with MPL requiring a tibial tuberosity transposition.