bluuebunny/crossref_metadata_2025_split huggingface dataset:
BİR EĞİTİM AİLE SAĞLIĞI MERKEZİNİN COVID-19 PANDEMİ DENEYİMİNİN İNCELENMESİ
Authors: ESMERAY Onur , ÖNER Can , CETİN Huseyin , ŞİMŞEK Engin Ersin 
Published: September 2023

Amaç: COVID-19 salgını Dünya Sağlık Örgütü tarafından pandemik durum ilan edilmiş ve bütün dünyada bir halk sağlığı krizine dönüşmüştür. COVID-19’un yarattığı hastalık yüküne bağlı olarak sağlık hizmetlerine erişimde kısıtlamalar ve aksamalar görülmüştür. Bu çalışmada COVID-19 pandemisinin birinci basamak sağlık hizmetleri üzerindeki etkisininin değerlendirilmesi amaçlanmıştır.
Yöntem: Tanımlayıcı desendeki çalışmanın verileri XXX Eğitim Aile Sağlığı Merkezi tarafından verilen sağlık hizmetlerinin kayıtlarının da geriye dönük olarak aile hekimliği bilgi sistemi üzerinden alınmıştır. Çalışmada sadece tanımlayıcı istatistik kullanılmıştır.
Bulgular: Çalışma sonunda da muayene hizmetlerinin pandemi döneminde %53,5 azaldığı görülmüştür. En büyük azalma %83,3 ile özellikli muayenelerde gerçekleşmiştir. Yenidoğan hizmetlerine bakıldığında pandemi döneminde yenidoğan sayısı azalmasına rağmen neonatal tarama programı ve işitme tarama testlerinin arttığı görülmüştür. Gebe hizmetlerinde ise doğum öncesi bakım izlemlerinde değişme olmadığı görülmektedir. Bağışıklama oranları pandemi döneminde %96 seviyesini korurken yetişkinlere verilen aile planlaması ve kanser taraması hizmetlerinde azalma olduğu görülmüştür.
Sonuç: Sonuç olarak pandemi döneminde otizm taramaları hariç çocuklara, bebeklere ve gebelere verilen sağlık hizmetlerinde bir gerileme olmadığı görülmüş, yetişkinlere verilen koruyucu sağlık hizmetlerinde salgın hastalığın etkisiyle aksamalar olduğu görülmüştür
On Levels of fast escaping sets and Spider's Web of transcendental entire functions
Authors: Singh Anand P. , Tomar Garima 
Published: September 2023

Let f be a transcendental entire function and let I(f) be the points which escape to infinity under iteration. Bergweiler and Hinkkanen introduced the fast escaping sets A(f) and subsequently, Rippon and Stallard introduced `Levels' of fast escaping sets . These sets under some restriction have the properties of "infinite spider's web" structure. Here we give some topological properties of the infinite spider's web and show some of the transcendental entire functions whose levels of the fast escaping sets have infinite spider's web structure.
Profinite Completions, Cohomology and JSJ Decompositions of Compact 3-Manifolds
Authors: Wilkes Gareth 
Published: September 2023

In this paper we extend previous results concerning the behaviour of JSJ decompositions of closed 3-manifolds with respect to the profinite completion to the case of compact 3-manifolds with boundary.
We also illustrate an alternative and perhaps more natural approach to part of the original theorem, using relative cohomology to analyse the actions of an-annular atoroidal group pairs on profinite trees.
Agricultura familiar e sistemas produtivos: produção de leite na região fronteira noroeste/RS
Authors: Büttenbender Pedro Luís , Thesing Nelson José , Silva Airton Rodrigues da , Lima Jesildo Moura de Lima Moura de , Amaral Volmir Ribeiro do , Galli Natália Vogt 
Published: September 2023

O artigo apresenta sistemas produtivos de uso extensivo, semi-intensivo e intensivo, na agricultura familiar, na região Fronteira Noroeste, no Rio Grande do Sul. Os sistemas contam com uma diversidade de paisagem, pela existência de diferentes tipos de agricultores, o que desafia as investigações em propriedades leiteiras. Essa realidade potencializa a pesquisa, que trabalha com método de abordagem quali-quantitativa, procedimento multicaso, técnica documental, análise e interpretação dos dados, média aritmética, software Microsoft Excel® e a análise de conteúdo. O sistema semi-intensivo apresentou a maior lucratividade e menor payback. O sistema intensivo apresentou a maior produção diária, preço médio recebido por número de vacas em lactação, área utilizada na atividade, produtividade média diária por animal, receita bruta, margem líquida. A composição dos custos sofreu alteração em função do sistema produtivo, onde o sistema extensivo apresentou o menor custo variável e o maior custo fixo, enquanto o semi-intensivo obteve o menor custo de oportunidade.
ANÁLISE DE VIABILIDADE ECONÔMICA PARA IMPLANTAÇÃO DE CULTIVO DE EUCALIPTO EM UMA PEQUENA PROPRIEDADE RURAL
Authors: RIBEIRO CÍCERO RODRIGUES , Longhini Tatielle Menolli , Santos Thalita Rabelo Almeida dos 
Published: September 2023

O eucalipto é uma alternativa para abastecimento das empresas de celulose e traz benefícios tanto para o produtor quanto para a comunidade. O aumento da demanda por madeira gerou uma rápida aceleração no plantio de eucalipto por parte dos proprietários rurais. Grande parte dos pequenos plantios realizados nesse período foram realizados sem nenhuma técnica adequada para verificar a viabilidade do investimento. A análise de viabilidade de investimentos é uma ferramenta de grande importância para o investidor que pretende dispor recursos em um projeto com o objetivo de gerar riqueza/lucro. Este trabalho teve como objetivo fazer essa análise em uma pequena propriedade rural no município de Peçanha – MG em que seu proprietário possui a intenção de realizar o plantio de eucalipto para posterior produção de celulose. Para o estudo foram utilizadas as ferramentas de Valor Presente Líquido (VPL), Taxa Interna de Retorno (TIR) e payback descontado. Todos os indicativos foram favoráveis ao plantio. O estudo considerou o corte do eucalipto com 7 anos após o plantio. O VPL resultante foi de R$95.887,89, a TIR 32,30% e o payback descontado de 5,32 anos. Os maiores custos foram orçados para o corte e transporte da madeira ao final do cultivo, e devido à baixa manutenção após os dois primeiros anos, o produtor considera que o investimento é adequado ao seu perfil mais conservador.
PERBEDAAN PENGARUH LATIHAN SERVIS TOPSPIN DENGAN LATIHAN SERVIS MENGAMBANG TERHADAP HASIL SERVIS ATAS PADA PERMAINAN BOLA VOLI ATLET BINA PUTRI MEDAN DELI TAHUN 2021
Authors: Claudius Samuel Malau  , Filli Azandi  
Published: September 2023

Penelitian ini bertujuan untuk mengetahui bentuk latihan bola voli manakah yang lebih besar pengaruhnya antara Bentuk latihan servis topspin dan bentuk latihan servis mengambang terhadap hasil servis atas pada siswa ekstrakurikuler bola voli atlet Bina Putri Medan Deli Tahun 2021. Metode penelitian yang digunakan dalam penelitian ini adalah metode experiment, dan pelaksanaan latihan yaitu dengan bentuk latihan servis topspin dan bentuk latihan servis mengambang. Populasi dalam penelitian ini adalah siswa ekstrakurikuler bola voli atlet Bina Putri Medan Deli Tahun 2021.berjumlah10 orang siswa. Jumlah sampel 8 orang dengan menggunakan teknik pengambilan rondom sampling, selanjutnya dibagi menjadi dua kelompok dengan menggunakan teknik macthing by pairing yaitu bentuk latihan servis topspin dengan bentuk latihan servis mengambang. dapat disimpulkan terdapat pengaruh yang signifikan dari latihan servis mengambang terhadap hasil servis atas siswa Ektrakurikuler Bola Voli atlet Bina Putri Medan Deli Tahun 2021. (3) Analisis hipotesis III dari rata-rata dan simpangan baku diperoleh t0.9336 serta tsebesar 1.94 dengan α = 0,05 (t< t ) berarti Ho diterima dan Ha ditolak. Jadi bentuk latihan servis topspin tidak lebih besar pengaruhnya dari pada bentuk latihan servis mengambangterhadap hasi servis atas pada siswa Ekstrakurikuler Bola Voli atlet Bina Putri Medan Deli Tahun 2021
A histological autopsy study of the thyroid gland in HIV infected adults at the University Teaching Hospital in Lusaka, Zambia
Authors: Muwowo S. , Mudenda V. , Marimo C. 
Published: September 2023

Background: Despite the high prevalence of Human Immunodeficiency Virus (HIV) in Zambia, not much is known about the spectrum of thyroid lesions in patients with Acquired Immune Deficiency Virus, (AIDS). Patients with AIDS have increased prevalence of thyroid function abnormalities. It is therefore postulated the thyroid gland would be involved in AIDS patients. This study focused on the histologic appearances of the thyroid gland in HIV and AIDS patients on post mortem. The findings will provide evidence based recommendations on the management of thyroid diseases in the HIV infected in Zambia.
Objective: The aim of the study was to determine the histological appearances of adult thyroid glands in patients who died of HIV related diseases at UTH in the period 2010 to 2012.
Materials and Methods: This research was a descriptive retrospective study of adult thyroid glands collected at autopsy during the period 2010 to 2012. The study took place at the University Teaching Hospital (UTH) in the Department of Pathology and Microbiology in Lusaka, Zambia. A total of 200 thyroid gland paraffin blocked samples were obtained from the parent study tissue bank by convenient sampling. The inclusion criteria included samples from adult HIV patients who were admitted to UTH and died in hospital. The Paraffin blocked thyroid tissue samples were processed according to standard histopathology laboratory protocols at UTH which included sectioning and staining with hematoxylin and eosin. The slides were examined at light microscopic level. Clinical data was obtained from the available case notes.
Results: The sample size was 200 thyroid glands of which 123(62%) were males. Thyroid histopathological lesions were seen in 111 (56%) of the cases, of which 60 (54%) were male. The lesions included: Interstitial fibrosis 104 (52%), nonspecific chronic thyroiditis 42 (21%). Infectious diseases included Mycobacterium tuberculosis 2 (1%) and Cryptococcus neoformans 1(0.5%).
Conclusion: These findings outline the importance of thyroid function testing in HIV infected patients who may have subclinical thyroid dysfunction and infection.
The effect of pulmonary tuberculosis on neurocognitive function in HIV infected adult patients in Lusaka, Zambia
Authors: Chinyama Jonathan , Ngoma MS , Menon AJ. , Hestad K , Heaton RK 
Published: September 2023

Objective: To explore the effects of Pulmonary Tuberculosis on neurocognitive functions in HIV+ adults in Lusaka, Zambia.
Materials and methods: In a retrospective and prospective case-control study, Global Deficit Score (GDS) was used as an overall measure for cognitive impairments between groups and also within the PTB+/HIV+ group, and Domain Deficit Scores (DDS) were used to summarize cognitive impairments within each of the seven domains. To examine group differences in neurocognitive status, we used Wilcoxon ranked sum tests to compare the performance between groups on neuropsychological test battery.
Results: Out of 324, only 244 were studied. Results indicated significant neurocognitive impairment in PTB+/HIV+ group than PTB-/HIV+ in the GDS, p<.001, significant lower CD4 cell count with a mean of 323 cells/μl compared to 510 cells//μl for the control group. The PTB+/HIV+ group, CD4 cell count was in the range 201-499 cells//μl compared to their cohort CD4 cell count above 500 cells//μl indicating immune compromise in the PTB+/HIV+. 95% of PTB+ were stages 3 and 4 indicating AIDS defining stage, whereas 95% of PTB negative were stage 1 suggesting immunocompetent. Linear regression model (p<.01), PTB status was predictive of GDS even while accounting for demographic and medical variables that have previously been associated with neurocognitive impairments. Specifically, a linear regression model identified PTB status (F=6.26, p < .02) as a significant predictor of Global Deficit Score (GDS). Age (F =3.21, p <.08) approached significance, while years of schooling (F =0.54), current WHO stage (F=1.41) and gender (F= .13) were not significant independent predictors of GDS (all ps > .10).
Conclusion: This study highlights the fact that PTB has neurocognitve impairment in HIV+ adult individuals. Findings of the present study show the presence of neuropsychological impairments in all the seven domains except motor in the PTB+/HIV+ adults in Lusaka district, Zambia.
A comparative study of Mycobacterium Tuberculosis in hospitalised adult HIV infected patients with normal and abnormal renal function at the University Teaching Hospital, Lusaka, Zambia
Authors: Liusha Namakando , Mulenga L , Chirwa L , Chanda D , Mweemba A 
Published: September 2023

Background: Mycobacterium tuberculosis (TB) remains a leading cause of mortality and morbidity worldwide, including Zambia, especially among those infected with the Human Immunodeficiency Virus (HIV). Both kidney dysfunction and TB have been shown to be highly prevalent among hospitalised HIV infected patients. Little is known about how TB and kidney dysfunction impact each other in HIV patients, and whether there is any association between the occurrence of kidney dysfunction and active TB infection in this population. This study was aimed at determining the prevalence and risk factors of active TB infection in HIV positive patients with and without kidney dysfunction.
Methods: This was an analytical cross-sectional study. Using simple random sampling, HIV positive patients on the medical wards were recruited in two arms (74 with & 59 without kidney dysfunction). Urine Lipoarabinomannan (LAM), TB blood culture, sputum culture and genexpert MTB/Rif were used for TB diagnosis. Data was analysed using STATA version 13.
Results: TB prevalence in all HIV positive hospitalized patients was 45%, and more prevalent in the kidney disease than non-kidney disease group (54% vs 35.59%; p=0.034). TB diagnosis pick up was comparable in the kidney disease and the non-kidney disease group using urine LAM and blood culture at 31.1% vs 22.2% and 8.9% vs 3.1% respectively, but lower using sputum culture; 12.5% vs 24.1%. Among kidney disease patients, a higher CD4 count > 200cells/μl was protective for active TB (P = 0.011). Severe immunosuppression (CD4 count < 200cells/μl) was 18.64% higher in the kidney dysfunction group compared to the non-kidney disease group (P=0.026). The only factor associated with active TB was male gender (P = 0.029); while Proteinuria in a TB patient was strongly associated with kidney disease (P < 0.001). Patients with WHO stage III/IV were likely to present with TB in both groups (P=0.004, 95% CI 1.47 - 7.20). Kidney dysfunction severity (measured by estimated glomerular filtration rate), age, antiretroviral therapy status and duration on combination antiretroviral therapy, history of TB contact and current cough, had no significant association with active TB in the two groups.
Conclusion: Patients with kidney disease are more likely to present with active TB infection than HIV infected patients with no kidney disease. Among patients with active TB, urinalysis can help predict renal dysfunction; while determinants of active TB in the general population are not similar to those in kidney disease patients.
GINKGO BILOBANING KIMYOVIY TARKIBI VA XALQ TABOBATIDA QO‘LLANILISHI
Authors: Asqarov Ibrohimjon Rahmonovich , Razzaqov Nabijon Alijonovich 
Published: September 2023

Ushbu maqolada Ginkgo biloba deb nomaladigan dorivor o‘simlikning kimyoviy tarkibi, uning biologik faolligi hamda isbotli tabobatda kasalliklarni davolash o‘rinlari haqida. Markaziy nerv sistemasining oziqlanishining buzilishi va shuning oqibatida xotiraning pasayishi hamda asabiylashish kabi xastaliklarda Ginkgo biloba o‘simligidan foydalanish yaxshi samara beradi.
Analisis Hukum Ekonomi Syari’ah Tentang Akad Ijarah Alat Pemanen Padi Combine Harvester (Studi Kasus di Kampung Simpang Asam Kecamatan Banjit)
Authors: Yansya Febri Yansya , Andriansyah Andriansyah 
Published: September 2023

Tujuan penelitian adalah Untuk mengetahui praktek akad ijarah alat panen padi combine harvester di Kampung Simpang Asam Kecamatan Banjit Kabupaten Way Kanan. Untuk mengetahui analisis hukum ekonomi syaria’ah terhadap praktek akad ijarah dalam alat panen padi combine harvester di Kampung Simpang Asam Kecamatan Banjit Kabupaten Way Kanan. Jenis penelitian ini adalah penelitian lapangan (field research) yang sifatnya deskriptif analisis, yaitu memaparkan fakta-fakta yang ada untuk selanjutnya dianalisis secara kualitatif dengan pola pikir induktif dan atau deduktif. Hasil penelitian didapat bahwa akad sewa mesin combine harvester di Kampung Simpang Asam berdasarkan adat kebiasaan masyarakat setempat yang dituangkan dalam perjanjian lisan antara pemilik mesin dan pemilik lahan, dilihat dari landasan hukum ekonomi syaria’ah yang bersumber dari Al-Qur’an dan As-Sunnah tentang sewa menyewa, maka sewa menyewa mesin pemanen padi di Kampung Simpang Asam Kecamatan Banjit Kabupaten Way Kanan dipandang sah dan dibenarkan, dengan alasan sewa menyewa mesin pemanen padi ini telah memenuhi syarat-syarat yang ditetapkan oleh hukum ekonomi syari’ah, terutama yang berkaitan dengan subyek yang berakad dan obyek sewa menyewa asalkan itu tidak mengubah nashnya.
De stand van de stelselherziening: op weg naar 1 januari 2024
Authors: Gierveld H.A.J. (Henk) 
Published: September 2023

De stand van de stelselherziening: op weg naar 1 januari 2024
Het artikel biedt een overzicht van hetgeen met name in de Eerste Kamer aan de orde is geweest ten aanzien van de besluitvorming over het ontwerp koninklijk besluit tot inwerkingtreding van de Omgevingswet met ingang van 1 januari 2024. Daarnaast gaat het artikel in op de verhouding tussen de minister en de Afdeling bestuursrechtspraak en de Eerste Kamer.
Reoperative and Non Reoperative Hirschsprung’s Disease in Associated with Clinicopathological Profile of the Proximal End of Resection in the Department of Anatomical Pathology, FMUI/CMH 2015-2019
Authors: Permata Warastridewi Arie , Krisnuhoni Ening 
Published: September 2023

Background
Hirschsprung’s disease (HD) is a developmental disorder of the enteric nervous system, which is characterized by the absence of ganglion cells in the submucosal and myenteric plexuses. The success of surgery is influenced by many factors, one of which is the presence of histopathological abnormalities in the proximal part of the HD rectosigmoid resection. The aim of this study is to determine whether there are any histological characteristics associated with Hirschsprung's disease that would necessitate reoperation at the Department of Anatomical Pathology Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital (FMUI/CMH).
Methods
This was an analytical study using a cross-sectional design and secondary data from the Department of Anatomical Pathology Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital (FMUI/CMH) archives between 2015 and 2019. At the proximal end, histopathological examinations were performed to determine mature ganglion, nerve thickening, normal ganglion number, perineural inflammation, and serositis. The patient's age at the time of surgery, gender, the type of surgery, and the patient's age at the time of reoperation were all recorded.
Results
From the 64 resection cases, 15 reoperation resection cases and 49 non-reoperation resection cases were obtained. Of the 15 reoperation cases, the histopathological investigation revealed fifteen cases of mature ganglion, ten cases of nerve thickening, and fourteen cases of normal ganglion. There was no perineural inflammation in fifteen cases, and no serositis in fourteen cases. A p value of 0.026 was obtained for the patient's age at the time of the operation.
Conclusion
There are several factors that determine pasients with Hirschsprung disease who undergo reoperation after resection. The age of the patient at the time of resection is one of the factors that can affect the occurence of reoperation in patients with Hirschsprung disease.
Anti-inflammatory Effect of Tamarillo (Solanum betaceum Cav.) Fruit Peel Ethanol Extract: Study of Carrageenan-Induced Buccal Mucosa on Rats
Authors: Syarafina Amiretta , Sudiono Janti 
Published: September 2023

Background
Inflammation is a local protective response by tissue damage. Tamarillo fruit peel ethanol extract has flavonoid as anti-inflammatory, anti-oxidant, inhibit cyclooxygenase and lipoxygenase as well as leukocyte accumulation. This study aims to determine anti-inflammatory effect of Tamarillo fruit peel ethanol extract on carrageenan-induced buccal mucosa of rats.

Methods
Extraction was done by maceration with 70% ethanol. The 30 rats divided into five groups, namely positive control (diclofenac sodium), negative control (NaCl), and extract doses of 70, 140 and 280 mg/kgBW. Carrageenan was injected as inflammation inducer in the right buccal mucosa. Macroscopic and microscopic observations were performed at three times, 24, 48, and 72 hours after carrageenan injection.

Results
At 24 hours, inflammatory cells of 70 mg/kg extract were 37, at 140 and 280 mg/kgBW were 18; positive and negative control as 35 and 405. At 48 hours, inflammatory cells of positive control were 22; extract of 70, 140, and 280 mg/kgBW were 21, 17, and 16 while negative control was 26. At 72 hours, positive and negative controls were 18 and 27. Extract of 70, 140, and 280 mg/kgBW had 20, 12 and 9 cells. Extract groups had no significant differences with the positive control (p>0.05) except for the 48th hours of 70 mg/kgBW however the extract groups showed significance with negative control (p<0.05). The lowest number cells (6) was at 280 mg/kgBW on 72 hours.

Conclusion
Tamarillo fruit peel ethanol extract is effective anti-inflammatory agent especially dose of 280 mg/kgBW on 72 hours.
Clinicopathological Profile of Ampulla of Vater and Pancreas Malignancies at Cipto Mangunkusumo Hospital in 2015-2019
Authors: Pramono Meike , Rini Handjari Diah 
Published: September 2023

Background
Malignancies of ampulla of vater and pancreas are often difficult to distinguish. Malignancies in ampulla of vater include malignancies in major duodenal papilla, distal common bile duct and pancreatic duct opening (Wirsung). The origin of the primary tumor, histopathological diagnosis and staging play a role in therapy and prognosis. WHO Classification of tumors of the digestive system, 2019 made changes in tumor staging following the system of the American Joint Committee on Cancer (AJCC), 8th edition. This study was conducted to determine types of pancreatic and ampullary malignancies, demographic distribution, location, profile, histomorphology and tumor staging changes in the 7th edition of the AJCC to 8th edition of the AJCC in the WHO Classification of tumors of the digestive system, 2019. The aim to determine clinicopathological profile of malignancies of ampulla of vater and pancreas as well as tumor staging changes based on AJCC edition 8.
Methods
Observational descriptive study on pancreatic and ampulla vater malignancy resection preparations at Department of Anatomic Pathology FKUI/RSCM, period January 2015 to December 2019 that met the inclusion criteria. Demographic evaluation, tumor location, histopathological profile and patient staging changes were carried out based on the 8th edition of AJCC.
Results
There were 27 cases of adenocarcinoma in ampulla of vater, 10 cases of pancreatic ductal adenocarcinoma, 1 case of mucinous cystic neoplasm with adenocarcinoma focus, 1 case of serous cystadenocarcinoma, 7 cases of PanNET, 2 cases of PanNEC, 3 cases of SPN, 1 case of MiNEN. Changes in pT were present in 29 cases. Changes in pN were present in 6 cases.
Conclusion
The diagnosis and pathological staging are in accordance with the 2019 WHO digestive system tumor classification. Tumor differentiation, presence or absence of lymphovascular invasion, perineural invasion and lymph node metastases and incision margin status are important histopathological parameters.