bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Pakar Diagnosa Penyakit Pada Ibu Hamil Menggunakan Metode Forward Chaining
Authors: Sundari Jenie , Wulandari Siti , Budiarti Yusnia , Nainggolan Esron Rikardo 
Published: July 2023

AN EXPERT SYSTEM FOR DISEASE DIAGNOSIS PREGNANT WOMEN USING FORWARD CHAINING METHOD. Health is one of the important factors for pregnant women in conducting daily activities. However, some pregnant women do not care about their body condition so there are many complaints, causing a disease in pregnant women. Pregnant women can be affected by pregnancy, the disease can be known from the symptoms it causes, but to know precisely what diseases suffered by pregnant women, requiring an expert or specialist doctor Content. In this study designed a system of experts based on the website using a rule base with the method of forward chaining inference aimed at helping pregnant mothers in diagnosing early pregnancy disease. This expert system is able to diagnose the disease suffered by the pregnant mothers according to the question of the symptoms asked to be answered by the pregnant women, so that the system will provide diagnostic results, details on diseases and treatment The disease.
Un sistema cuasiparlamentario, republicano y bicameral: una propuesta para Chile
Authors: Larraín Guillermo , Voigt Stefan 
Published: July 2023

Chile tiene una larga tradición presidencial. Algunos plantean que es imposible pensar en no elegir directamente al presidente. Frente a esta ‘restricción sociológica’, un análisis completo debe reconocer que el presidencialismo tiene problemas en particular respecto de lo que denominamos una ‘restricción estructural’: la fragmentación partidaria. En ese contexto, la posibilidad de tener regularmente presidentes de minoría y falta de disciplina en el Congreso es un riesgo. Proponemos un sistema cuasiparlamentario (Irlanda sería el caso más cercano), en el que el presidente usa toda la legitimidad de ser la única autoridad electa directamente a nivel nacional para velar por la continuidad del Estado, por la prevalencia de los intereses públicos de largo plazo y para actuar como árbitro en momentos de gran complejidad
política. Nuestra propuesta incorpora características de sistemas parlamentarios, entre ellos la necesidad de constituir mayorías en la Cámara de Diputados que apoyen el programa de gobierno y la posibilidad de realizar votos de censura constructivos. El sistema es bicameral con niveles variables de asimetría en función de la mayoría en la Cámara Alta. En comparación con el sistema semipresidencial, nuestra propuesta reduce la capacidad del presidente para interferir en las acciones ejecutivas a corto plazo, mientras que privilegia instrumentos fuertes para garantizar la continuidad del Estado. Esta configuración promueve una mejor gobernanza porque los gobiernos deben tener mayoría parlamentaria, fomenta la rendición de cuentas porque habrá mejor escrutinio sobre las promesas de campaña, así como la estabilidad democrática porque es un sistema más flexible y con más herramientas para enfrentar crisis. También está diseñado para promover la elaboración de políticas con una mirada a más largo plazo y así propiciar el desarrollo económico.
Effect of initial stroke care bundle on clinical outcomes among patients with acute ischemic stroke
Authors: Mohamed Ragaa Dahi , Hamad Amal H. , Abouzied Warda R. 
Published: July 2023

Background
Stroke care bundles are evidence-based practices in the management of acute ischemic stroke that are rapidly changing. Early detection of stroke symptoms and prompt treatments can result in a positive outcome. Specialized care in the emergency room during the acute phase and the first week in a neurological ICU or stroke unit for follow-up can enhance the overall prognosis.

Aim
To evaluate the effect of implementing an initial stroke care bundle on clinical outcomes among patients with acute ischemic stroke.

Patients and methods
A quasi-experimental research design was used. A convenient sample of 60 critically ill adult patients who were admitted to the emergency care unit and neurology ICU was included. The patients were tested using an initial stroke care bundle during 7 days of admission to the neurological ICU and then followed up another week in the medical ward and 2 weeks in the outpatient clinic. The data were collected using three tools developed by the researchers.

Results
There were highly statistically significant differences between the control and study groups regarding improving vital signs, neurological status, and hydration status on admission, third and seventh days after admission, and during 3-week follow-up. Moreover, patients with acute stroke who received the initial stroke care bundle had a statistically significant reduction in mortality rate, higher independence, and normal prefeeding assessment compared with those who received routine care on admission, 3 and 7 days after admission, and during 3-week follow-up.

Conclusion
Implementing an initial stroke care bundle can improve the prognosis of patients with acute ischemic stroke and decrease the number of deaths.

Recommendation
Recent stroke care bundle should be integrated into the management of patients with acute stroke to improve the patients’ outcomes.
Effect of progressive muscle relaxation technique on sleep quality among patients with chronic obstructive pulmonary disease
Authors: Eldefrawy Mohamed M.I. , Khalil Nahla S. , Ibrahim Eman K. , Ali Fatma S. 
Published: July 2023

Background
Sleep quality is often poor in patients with chronic obstructive pulmonary disease (COPD), and patients frequently report difficulty in falling asleep, nocturnal awakening, and insomnia.

Aim
The aim was to assess the effect of progressive muscle relaxation technique (PMRT) on sleep quality among patients with COPD.

Research hypothesis
H0: Patients who will receive progressive muscle relaxation exercise will have no change in their sleep quality score as compared with their initial assessment score.

Design
A quasi-experimental single-group pretest/post-test research design was used.

Setting
This study was conducted at one of the selected critical care units affiliated to Cairo University Hospitals.

Sample
A purposive sample consisting of 37 adult patients diagnosed with COPD were recruited throughout a period of 12 months.

Tools
Two tools were used to collect data: first, demographic characteristics and medical data sheet, and second, Pittsburgh sleep quality index.

Results
There were significant statistical differences among the patients regarding all sleep problems (P≤0.05) before and after implementation of PMRT except for high temperature (P=0.25) and seeing bad dreams (P=0.32), so the frequencies of sleep troubles become lesser after implementation of the PMRT. Moreover, there were highly significant statistical differences (P≤0.00) between pretest and post-test regarding sleep quality over all the period of ICU stay.

Conclusion
It can be concluded that the application of PMRT has a positive effect on sleep problems among patients with COPD and frequencies of sleep troubles became much lesser after implementation of the PMRT.
Assessment of serum microRNA-21 and miRNA-205 as diagnostic markers for stage I and II breast cancer in Indian population
Authors: Rama Kanchi , Bitla Aparna R , Hulikal Narendra , Yootla Mutheeswaraiah , Yadagiri Lakshmi Amancharla , Asha T , Manickavasagam M , Srinivasa Rao PVLN 
Published: July 2023

Background:
Current markers (carcinoembryonic antigen [CEA] and carbohydrate antigen 15-3 [CA15-3]) lack sensitivity in diagnosis of breast cancer. The aberrantly expressed circulating miRNAs were shown as diagnostic markers in breast cancer. However, there are very few studies from the Indian population. We studied the diagnostic utility of miRNA-21, miRNA-155 and miRNA-205 compared to CEA and CA15-3 in stage I and II breast cancer patients.

Materials and Methods:
Sixty newly diagnosed women with stage I/II breast cancer and 20 healthy controls were recruited. Expression of circulating miRNAs was studied using reverse transcription-polymerase chain reaction, whereas CEA and CA 15-3 were analyzed by enzyme-linked immunosorbent assay.

Results:
miRNA-21 and miRNA-155 were upregulated, miRNA-205 down-regulated (P < 0.05) and serum CEA and CA15-3 levels increased in breast cancer patients (P < 0.001). Receiver operating characteristic curve analysis showed significant area under curve (AUC) for all markers (0.656 to 0.993; P = 0.015 to <0.001) validating their diagnostic potential. Unlike CEA and CA15-3, miRNAs retained their sensitivity even at higher cut-offs (95% CI of mean). Logistic regression analysis showed significant association between disease and marker positivity for miRNA-21 and miRNA-205 but not for miRNA-155. Combining CA15-3 with miRNAs did not improve their diagnostic performance. However, combining CEA with either miRNA-21 (AUC = 0.742; P < 0.001 versus AUC = 0.656; P = 0.018) or miRNA-205 (AUC = 0.733; P < 0.001 versus AUC = 0.700; P < 0.001) increased its diagnostic performance.

Conclusion:
Our study shows miRNA-21 and miRNA-205, are useful as diagnostic markers for breast cancer in the Indian population and combination of these miRNAs with CEA but not with CA 15-3 improved their diagnostic performance.
Efficacy of Hinged Ankle–Foot Orthosis on Gait Improvement of Children with Spastic Diplegic Cerebral Palsy: A Literature Review
Authors: Kumar Raj , Prakash Achintya 
Published: July 2023

Purpose:
The purpose is to study the effect of hinged ankle–foot orthosis (HAFO) on gait kinematics and temporospatial parameters of children with diplegic cerebral palsy.

Methods:
A literature search has been conducted from 2005 to 2022 to find the studies measuring the effect of HAFO on children with diplegic spastic cerebral palsy (CP) during gait through various bibliographic databases: PubMed, Scopus, EMBASE, O and P Virtual Library and Google Scholar.

Results:
We found 96 pieces of potentially relevant literature from which only six studies met the inclusion criteria were included. One hundred and fifty-three participants, with a mean age of 8.6 years (4–17 years), were investigated, of which 128 were spastic diplegic CP. Among spastic diplegic, 45 individuals were identified as walking with true equinus gait and 34 with jump gait. Gait parameters of participants were evaluated with ankle–foot orthoses (AFO) (hinged, solid and supramalleolar orthosis), and barefoot walking conditions showed improvement in some kinematic and spatial-temporal parameters, making their gait closer to that of typically developing children.

Conclusion:
HAFO was found very satisfactory, as it improves dynamic stability and ankle range of motion resulting in a more natural gait in children with spastic diplegic CP.
Gas‐Liquid Flow‐Induced Characteristics of Dispersed Liposome‐Based Particles
Authors: Yoshimoto Makoto 
Published: July 2023

AbstractLiposomes are closed bilayers of phospholipids formed in aqueous media. The hydrodynamic property of colloidal dispersions of liposomes is one of the factors which alter the structure of liposomes. The present review article discusses the mechanistic aspects of the deformation, breakage, and fusion of liposomes in different liquid shear flows. Then, characteristic features reported with respect to the particles consisting of liposomes and bubbles are discussed to explore the role of shear flows induced by the acoustically active bubbles. Furthermore, the gas‐liquid flow‐induced characteristics of liposomes are described for their application to kinetically controllable enzymatic reactions in bubble‐column bioreactors.
Culinary spices and herbs in managing early and long‐COVID‐19 complications: A comprehensive review
Authors: Maurya Dharmendra Kumar , Sharma Deepak 
Published: July 2023

AbstractHuman race is preparing for the upsurge and aftermath of COVID‐19 pandemic complicated by novel variants, new waves, variable mortality rate, and post‐COVID complications. Despite use of repurposed drugs, symptomatic treatments and licensing of multiple vaccines, the daily number of cases and rate of transmission are significant. Culinary spices and herbs have been historically used in pandemic and non‐pandemic times to reduce respiratory viral burden. Specific food items and culinary spices can boost the levels of protective immunity and also offer therapeutic benefits against impervious bugs via well‐known as well as less‐known but scientifically testable mechanisms. Here, we analyzed the phytochemicals profile of Ayurvedic herbs and inferred from the clinical trials/observational studies to provide a focused and succinct perspective on the relevance of “food‐based” traditional decoction to moderate COVID‐19 disease and long‐COVID via modulation of immunity and reinstatement of homeostasis. We also underscore the druggable targets in pathogenesis of COVID‐19 which are relevant to the ongoing clinical trials using spices and herbs. This information will provide a strong scientific rationale for standardization of the traditional herbs‐based therapies and adopting the use of herbs, spices, and their formulations for reducing SARS‐CoV‐2 transmission, long‐COVID symptoms, and COVID‐19 disease progression.
Prenatal Exposure to Cannabis and Risk of Major Structural Birth Defects
Authors: Delker Erin , Hayes Shana , Kelly Ann E. , Jones Kenneth L. , Chambers Christina , Bandoli Gretchen 
Published: July 2023

OBJECTIVE:To review and perform a meta-analysis of observational studies that examined associations between prenatal cannabis exposure and major structural birth defects.DATA SOURCES:Information sources included Google Scholar, BIOSIS, PubMed/MEDLINE, EMBASE CINAHL, and ClinicalTrials.gov.METHODS OF STUDY SELECTION:Study titles and abstracts were reviewed with Abstrackr software. We included observational studies that examined the risk of major structural birth defects in people who used cannabis during pregnancy compared with those who had not used cannabis. We excluded case reports, ecologic studies, conference abstracts, manuscript preprints, studies designed to examine effects of cannabis used concurrently with other drugs, and studies that included synthetic cannabinoids. This process yielded 23 studies that analyzed data from birth years 1968–2021.TABULATION, INTEGRATION, AND RESULTS:We clustered and meta-analyzed measures of association for birth defects by anatomic group. Eleven articles reported an association between cannabis use and the risk of a nonspecific outcome (eg, congenital anomaly). We estimated a pooled odds ratio of 1.33 (95% CI 1.14–1.56) and a pooled adjusted odds ratio (aOR) of 1.22 (95% CI 1.00–1.50). Anatomic groups examined were cardiac (nine studies), oral cleft (three studies), digestive (four studies), genitourinary (three studies), musculoskeletal (seven studies), and nervous system (five studies). Across most outcomes, we reported positive pooled unadjusted associations that were usually attenuated after the inclusion of only adjusted estimates. Two specific anomalies, with limited data, had pooled effect estimates that did not attenuate to the null after adjustment: Ebstein anomaly (two studies, aOR 2.19, 95% CI 1.25–3.82) and gastroschisis (five studies, aOR 2.50, 95% CI 1.09–5.740).CONCLUSION:Studies examining associations between prenatal exposure to cannabis and major structural birth defects were heterogeneous. Most published effect estimates were unadjusted and scored low on our risk-of-bias assessment. Overall, we found inconsistent evidence to suggest that prenatal cannabis exposure is associated with birth defects. However, findings related to specific anomalies should be considered in further research.SYSTEMATIC REVIEW REGISTRATION:PROSPERO, CRD42022319041.
Number of segments with motion abnormalities is better correlated with infarct size in acute myocardial infarction
Authors: Yu Fan , Tang Ge , Chen Yun-An , Zhang Peng-Ying , Ren Fei , Zhang Jie , Zheng Xiao-Zhi 
Published: July 2023

Background
The relationship between the number of segments with motion abnormalities (SMA) on the bull’s-eye plots of speckle-tracking echocardiography (STE) and myocardial infarct size (MIS) on late gadolinium-enhanced cardiac MRI (LGE-cMRI) has not been well characterized. This study aimed to determine MIS using the number of SMA in patients with acute myocardial infarction (MI).

Methods
Left ventricular two-dimensional STE and LGE-cMRI were performed in 380 patients with ST-segment elevation MI within 48 h and 5–6 days after primary percutaneous intervention, respectively.

Results
Patients with impaired global and regional myocardial strain, work and greater number of SMA had significantly larger infarcts (P < 0.05). Multivariate logistic regression analysis that included myocardial strain, work, and number of SMA showed that total number of SMA [odds ratio (OR) = 1.976; 95% confidence interval (CI): 1.539–2.538, P < 0.0001], the number of segments with paradoxalic systolic movements (SPSM, OR = 3.703; 95% CI: 2.112–6.493, P < 0.0001) were independent risk factors of large MIS (>19%). The area under receiver operating characteristic curve (AUC) of 0.904 (0.866~0.942) for total number of SMA was superior to that for global longitudinal strain (GLS, AUC = 0.813, 0.761~0.865), global work efficiency (GWE, AUC = 0.794, 0.730~0.857) and number of SPSM (AUC = 0.851, 0.804–0.899) to predict a large MIS (P < 0.05). The optimal cutoff value of total number of SMA was 7, with a sensitivity of 85.31%, a specificity of 81.48%, and an accuracy of 83.27%.

Conclusion
Total number of SMA is better associated with infarct size, which provided an incremental prognostic value above established prognostic parameters such as GLS and GWE.
A survey of therapists’ experience of ending therapy with people with intellectual disabilities
Authors: Dunn Yasmine , Summers S.J. (Ash) , Dagnan Dave 
Published: July 2023

Purpose
A range of adaptations and therapy processes have been explored in relation to therapy with people with intellectual disabilities; however, there remain a few areas of therapy practice that have not yet been considered in depth. This study aims to report the results of an online survey of the practice of therapists working with people with intellectual disabilities in managing endings in therapy.

Design/methodology/approach
Thirty-one therapists working with people with intellectual disabilities responded to an online survey. The data were analysed using reflexive thematic analysis.

Findings
Three superordinate themes were identified: Theme 1 was “preparing for a therapeutic ending” with subordinate themes of “planning early”, “providing boundaries” and “validating feelings”; Theme 2 was “providing a therapeutic ending”, with subordinate themes of “a collaborative decision” and “fostering growth”; and the third theme was “post-ending issues” in which participants acknowledged a “spectrum of emotion”, and, in the case of difficult endings, a sense of “unfinished business”.

Originality/value
This is the first systematic exploration of therapy endings as described by therapists working with people with intellectual disabilities. The authors discuss implications for practice and further areas of research.
‘What a waste of time’: An examination of cybersecurity legitimacy
Authors: Cram W. Alec , D'Arcy John 
Published: July 2023

AbstractManagers who oversee cybersecurity policies commonly rely on managerial encouragement (e.g., rewards) and employee characteristics (e.g., attitude) to drive compliant behaviour. However, whereas some cybersecurity initiatives are perceived as reasonable by employees, others are viewed as a ‘waste of time’. This research introduces employee judgements of cybersecurity legitimacy as a new angle for understanding employee compliance with cybersecurity policies over time. Drawing on theory from the organisational legitimacy and cybersecurity literature, we conduct a three‐wave survey of 529 employees and find that, for each separate wave, negative legitimacy judgements mediate the relationship between management support and compliance, as well as between cybersecurity inconvenience and compliance. Our results provide support for cybersecurity legitimacy as an important influence on employee compliance with cybersecurity initiatives. This is significant because it highlights to managers the importance of not simply expecting compliant employee behaviour to follow from the introduction of cybersecurity initiatives, but that employees need to be convinced that the initiatives are fair and reasonable. Interestingly, we did not find sufficient support for our expectation that the increased likelihood of a cybersecurity incident will moderate the legitimacy‐policy compliance relationship. This result suggests that the legitimacy perceptions of employees are unyielding to differences in the risk characteristics of the cybersecurity incidents facing organisations.
Social network, Biden approval, and pediatric COVID‐19 vaccine uptake
Authors: Hao Feng 
Published: July 2023

AbstractThis study aims to estimate the pediatric COVID‐19 vaccine uptake and the impact of social network and Biden approval. A national survey was conducted by Qualtrics from September 26 to 19 October 2022, and respondents who identified as primary guardians of children under 18 are included in this study. Findings show that parents are more likely to vaccinate children between 12 and 17 than children between 5 and 11 or below 5. The means of measures for social network and Biden approval for parents who have vaccinated children across different age groups are significantly higher than the corresponding means for parents whose children remain unvaccinated. Structural equation modeling results suggest the social network and Biden approval positively affect parents' decision to vaccinate children. The former predictor also mediates the latter on the outcome measure. The findings are significant when analyzing the sample of parents with children over five. These findings contribute to the literature and have policy implications for leveraging interventions and optimizing vaccination for children.
BEHAVIOUR OF NUTRITIVE ELEMENTS AND HEAVY METALS IN CAI RIVER MOUTH AND NHA TRANG BAY
Authors: Vinh Le Thi , Thom Pham Thi , Thu Nguyen Hong , Kiem Duong Trong , Tam Pham Huu 
Published: July 2023

The behaviour of nutrients (N and P) and heavy metals (Zn, Cu, Pb and Fe) was investigated of Cai river mouth and southwest side of Nha Trang bay. The acquired results showed that: P, Pb and Fe total concentrations decreased noticeably in sea water area while N decreased insignificantly. They were mainly accumulated in river (lower Xuan Phong dam) and nearby Cai river mouth. This area could be expanded in flooding period. Contrarily, Zn and Cu rarely participated in the formation of floes (they mainly existed in dissolved phase). Deposited materials were derived from natural sources and substances formed when flocculation occurs in the freshwater-saltwater transition area. They were mainly N, P, Pb and Fe. Material exchange between dissolved and suspended phase was found only in the case of Pb. Nutritive elements and heavy metal contents in mud fraction of sediment were higher in river and river mouth area. Deposition rate of N and P was rather high in Nha Trang bay. Among the heavy metals, Fe and Pb were higher accumulation rate in comparison with Cu and Zn. The building of Xuan Phong dam of salt prevention can increase the accumulation of these contaminants in river bed sediment.