bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanoreactor Engineering Can Unlock New Possibilities for CO2 Tandem Catalytic Conversion to CC Coupled Products
Authors: Goksu Ali , Li Haitao , Liu Jian , Duyar Melis S. 
Published: May 2023

AbstractClimate change is becoming increasingly more pronounced every day while the amount of greenhouse gases in the atmosphere continues to rise. CO2 reduction to valuable chemicals is an approach that has gathered substantial attention as a means to recycle these gases. Herein, some of the tandem catalysis approaches that can be used to achieve the transformation of CO2 to CC coupled products are explored, focusing especially on tandem catalytic schemes where there is a big opportunity to improve performance by designing effective catalytic nanoreactors. Recent reviews have highlighted the technical challenges and opportunities for advancing tandem catalysis, especially highlighting the need for elucidating structure‐activity relationships and mechanisms of reaction through theoretical and in situ/operando characterization techniques. In this review, the focus is on nanoreactor synthesis strategies as a critical research direction, and discusses these in the context of two main tandem pathways (CO‐mediated pathway and Methanol‐mediated pathway) to CC coupled products.
Commissuroplasty using the triangular cheek flap in patients with free flap reconstruction of through and through buccal defects
Authors: Dang Rushil R. , El Abbadi Sam , Tsao Chung‐Kan 
Published: May 2023

AbstractExtensive resections of advanced stage oral cavity cancers can sometimes lead to significant through and through buccal defects with compromise of the oral commissure/lips. Post free flap reconstruction, such patients often require a secondary delayed commissuroplasty to assist with improved oral function and quality of life. In current literature, limited methods exist for free flap commissuroplasty with some key limitations, particularly their negative impact on buccal sulcus or oral vestibule. Our technique of the triangular cheek flap commissuroplasty allows the surgeon to reconstruct a neo‐commissure without compromising the oral vestibular depth or decreasing mouth opening. Through this pictorial essay we describe a detailed surgical technique for secondary reconstruction of the oral commissure.
Therapeutic effect of umbilical cord blood cells on spinal cord injury
Authors: Zhang Jun‐Yan , Steven Z. Du , Liao Ke‐Hua 
Published: May 2023

AbstractSpinal cord injury (SCI) is a nervous system disease characterized by sensory and motor dysfunction, axonal apoptosis, decreased vascular density, and inflammation. At present, surgical treatment, drug treatment, and cell therapy can be used. Surgical treatment can improve motor and independent function scores, and drug treatment can promote the recovery of neurons in the spinal cord, but only improve symptoms. Complete recovery of SCI has not yet been achieved. However, the differentiation of stem cells brings hope for the treatment of SCI. Umbilical cord blood cells (UCBs) are ethically readily available and can repair neuronal damage. However, it is still unclear how they can improve symptoms and repair nerve severity. In this paper, the role of UCBs in the treatment of SCI is described in detail from different aspects such as behavior, morphology, and molecular expression changes, so as to provide new ideas and theoretical directions for future research.
Assessing the social determinants of mental health in counseling practice
Authors: Neal Keith Sheerah , Coleman Monica L. , Hicks Becton Latasha Y. , Springfield Janita 
Published: May 2023

AbstractEvery counselor–client interaction is an opportunity for mutual learning through inquiry, listening, exploring, and understanding about a client's experiences with development and well‐being. Given the convergence of multiple sociopolitical events and systems that impact mental health and well‐being, we issue a call to increase promotion and uptake of preventative mental health strategies by assessing the social determinants of mental health (SDMH) in counseling practice. We contend that counselors are uniquely prepared to assess the SDMH at the intrapersonal, interpersonal, and environmental levels. Therefore, we review the parallels between counseling frameworks and the SDMH with the aim of explaining why and how counselors should assess the SDMH. Specifically, we describe ways that counselors can use their foundational skills and expertise in assessment procedures to identify client needs, as well as potential individual and community interventions. We outline a four‐phased approach for assessing the SDMH in counseling practice and provide implications for improving counseling outcomes.
A review on the versatility of Carica papaya seed: an agrogenic waste for the removal of organic, inorganic and microbial contaminants in water
Authors: Bayode Ajibola A , Anthony Eric T , Ore Odunayo T , Alfred Moses O , Koko Daniel T , Unuabonah Emmanuel I , Helmreich Brigitte , Omorogie Martins O 
Published: May 2023

AbstractThe advent of civilization, coupled with growing industrialization in many countries, is placing more demand on the available water sources. At the same time, the daily surge in wastes generated by man's anthropogenic activities has led to microbial, organic and inorganic contamination of water sources. Based on available evidence, significant research efforts are being made into the use of low‐cost agricultural materials such as Carica papaya seed (CPS) in the removal of these contaminants from water sources in a bid to provide clean water. In the present review, the organic, inorganic and microbial contaminants in waters were elucidated. Furthermore, the chemical composition of the CPS was illustrated. The adsorption capacity and efficiency of CPS and their composites in the remediation of the selected contaminants were discussed while identifying the various factors affecting the adsorption efficiency. Finally, the reusability of this agricultural material was discussed. Solution pH was identified as a major factor influencing the sorption process. The high removal efficiency reported in the studies that adopted CPS showed its vast potential in the elimination of contaminants from water sources. Also, the regenerative potential of the adsorbent over several cycles indicated its long‐term use. The economic feasibility and environmental sustainability afforded by using CPS chart a path for further investigation into the use of other low‐cost agricultural materials in the elimination of environmental contaminants. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Identification of tunnel structures in manganese oxide minerals using micro‐Raman spectroscopy
Authors: Vermeersch Eva , Košek Filip , De Grave Johan , Jehlička Jan , Vandenabeele Peter , Rousaki Anastasia 
Published: May 2023

AbstractManganese oxides have attracted the interest of many researchers due to their broad application field. These oxides possess various electrochemical, adsorption and catalysis properties and are as such applied in the industrial context, for example, steel industry, catalysis and removal of toxins in the ground or in waste water. In the archaeometrical field, manganese oxides have been used as pigments on various artefacts such as pottery and rock art paintings. The diversity of manganese oxide applications highlights the need for a well‐defined Raman spectroscopic database with correct characterization of these compounds. However, identification of manganese oxides by Raman spectroscopy is challenging due to the wide variety of manganese oxides, and manganese oxides are weak Raman scatterers and are susceptible under the laser light. As such, characterization by Raman spectroscopy is not straight forward. In this research, we have focussed on seven natural, mineral (tunnel) samples that were identified by micro‐Raman spectroscopy using two different laser wavelengths (785 and 532 nm). The experimental conditions were controlled to not introduce any modifications (degradation and/or phase transition) of the manganese oxide species. Both lasers have proven to be successful and were able to retrieve well‐characterized Raman spectra for each of the manganese oxide phase, which were compared with published literature.
In situ dynamic rheological analysis of raw yam tubers: a potential phenotyping tool for quality evaluation
Authors: Otegbayo Bolanle Omolara , Tran Thierry , Ricci Julien , Gibert Olivier 
Published: May 2023

AbstractBackgroundMost rheological analyses in yam have been done on starch gels, which requires starch extraction from the tubers. In situ rheology bypasses the need of starch extraction and relies on the original cell structure and complex matrix organization under stress or strain. Dynamic rheological properties of tuber from 16 accessions belonging to four yam species (Dioscorea rotundata, D. alata. D. bulbifera and D. dumetorum) were investigated for potential use as a medium throughput phenotyping screening tool that can indicate the quality of yam food products or their industrial potentials.ResultsRheographs of the tubers illustrated differences in the structure of D. bulbifera compared to other yam species. High initial storage modulus (G′) of yam parenchyma indicated tubers with strong and rigid structure which do not lose their structural integrity easily on heating. Dioscorea rotundata and D. alata varieties exhibited a lower temperature at which gelatinization took place (Tgel) equivalent to the irreversible transition during starch gelatinization (75.3 and 79.8 °C) and took shorter time (867 and 958 s, respectively) to reach the G′ maximum, compared to other species. The stress relaxation test showed that the higher the dry matter of the tubers, the higher the work to rupture the structure.ConclusionRheological characteristics G′, loss modulus (G″), swelling capacity and Tgel showed potential as suitable quality indicators for yam products. In situ rheological characterization of yam tubers could be used as an instrumental screening tool to phenotype for quality in yam products. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
On the linearization of infinite‐dimensional random dynamical systems
Authors: Backes Lucas , Dragičević Davor 
Published: May 2023

AbstractWe present a new version of the Grobman–Hartman's linearization theorem for random dynamics. Our result holds for infinite‐dimensional systems whose linear part is not necessarily invertible. In addition, by adding some restrictions on the nonlinear perturbations, we do not require for the linear part to be nonuniformly hyperbolic in the sense of Pesin but rather (besides requiring the existence of stable and unstable directions) allow for the existence of a third (central) direction on which we do not prescribe any behavior for the dynamics. Moreover, under some additional nonuniform growth condition, we prove that the conjugacies given by the linearization procedure are Hölder continuous when restricted to bounded subsets of the space.
The effects of female executives on financial statement comparability
Authors: Yan Zehao , Zhang Xianfeng , Liu Suyi 
Published: May 2023

AbstractThis study uses data from China to investigate the impact of female executives' proportion on a firm's financial statement comparability. We find that having female executives can improve a firm's financial statement comparability, particularly in the presence of a key female executive. Furthermore, we find that female executives improve firms' corporate governance and internal control quality, which in turn enhances financial statement comparability. Importantly, this impact exists only in large firms, non‐state‐owned firms, and firms domiciled in mature markets. Overall, our study reveals this mechanism and examines the conditions under which gender‐specific characteristics can affect corporate accounting quality.
Interaction between APOE, APOA1, and LPL Gene Polymorphisms and Variability in Changes in Lipid and Blood Pressure following Orange Juice Intake: A Pilot Study
Authors: Fraga Layanne Nascimento , Milenkovic Dragan , Coutinho Camille Perella , Rozenbaum Adriana Campos , Lajolo Franco Maria , Hassimotto Neuza Mariko Aymoto 
Published: May 2023

ScopeChronic orange juice intake is associated with reduced risk of cardiovascular disease, however, a large inter‐individual variability in response to orange juice for lipid profile and blood pressure has been observed. This heterogeneity in responsiveness could be associated with single nucleotide polymorphism (SNP), which has not been previously addressed. This study aims to investigate the influence of SNP in apolipoprotein E (APOE), apolipoprotein A1 (APOA1), mevalonate (MVK), and lipase lipoprotein (LPL) genes in the biological response after chronic orange juice intake.Methods and resultsForty‐six volunteers ingested 500 mL daily for 60 days and blood pressure and biochemical parameters are measured. Also, SNPs in APOE, APOA1, MVK, and LPL genes are genotyped in the volunteers that are medium/high excretors of flavanone metabolites. Genotypes CC (APOA1), AA, and GG (LPL) are associated with positive health effects of orange juice and the CC (APOE), GG (APOA1), GG, and AA (LPL) genotypes are associated with no effects of orange juice consumption (p< 0.05).ConclusionThese results identify for the first‐time SNP associated with effects of orange juice on lipid levels and blood pressure, results that may provide bases for future precise nutritional recommendations regarding this flavanone‐rich food to lower the risk for cardiovascular disease.
Flexural and tensile behavior of Kulkual fiber andTiB2particles reinforced epoxy composites
Authors: Selman Keyredin , Shahapurkar Kiran , Chenrayan Venkatesh , Alamir Mohammed A. , Alarifi Ibrahim M. , Tirth Vineet , Alghtani Abdulaziz H. , Algahtani Ali , Al‐Mughanam Tawfiq 
Published: May 2023

AbstractNovel composite comprising of Kulkual fibers and Titanium diboride (TiB2) filler reinforced epoxy composites is investigated in the current work. Kulkual also known as Opuntia ficus‐indica is a plant abundantly found throughout Ethiopia are utilized in the form fibers in combination with TiB2as reinforcement to synthesize epoxy matrix composites. Six types of composites including neat epoxy are fabricated using varying content of Kulkual fibers (0, 2.5, 5, 7.5, and 10 vol%) and fixed TiB2content of 5 vol%. The fibers were obtained by drying the leaf‐like stem of Kulkual and collecting the skeleton structure found in cladodes. Alkaline treatment of Kulkual fiber to study its physical properties was also investigated. All composites' tensile moduli rise with increasing fiber content and are between 21% and 162% higher than the pure epoxy. All the composites tensile strength increase in the range from 43% to 211% compared to neat epoxy with EK‐10 composite revealing the greatest improvement. Flexural properties of all the composites increase with increase in Kulkual fiber content in comparison with neat epoxy. Good bonding of constituents and alkaline treatment of fibers results in enhanced properties of composites. Finally, fractured surfaces are analyzed with scanning electron micrographs to recognize structure property correspondences.
Combination of antidepressants and antipsychotics as a novel treatment option for psychosis in Alzheimer's disease
Authors: Fan Peihao , Zeng Lang , Ding Ying , Kofler Julia , Silverstein Jonathan , Krivinko Joshua , Sweet Robert A. , Wang Lirong 
Published: May 2023

AbstractPsychotic symptoms are reported as one of the most common complications of Alzheimer's disease (AD), in whom they are associated with more rapid deterioration and increased mortality. Empiric treatments, namely first and second‐generation antipsychotics, confer modest efficacy in patients with AD and with psychosis (AD+P) and themselves increase mortality. Recent studies suggested the use and beneficial effects of antidepressants among patients with AD+P. This motivates our rationale for exploring their potential as a novel combination therapy option among these patients. We included electronic medical records of 10,260 patients with AD in our study. Survival analysis was performed to assess the effects of the combination of antipsychotics and antidepressants on the mortality of these patients. A protein–protein interaction network representing AD+P was built, and network analysis methods were used to quantify the efficacy of these drugs on AD+P. A combined score was developed to measure the potential synergetic effect against AD+P. Our survival analyses showed that the co‐administration of antidepressants with antipsychotics have a significant beneficial effect in reducing mortality. Our network analysis showed that the targets of antipsychotics and antidepressants are well‐separated, and antipsychotics and antidepressants have similar Signed Jaccard Index (SJI) scores to AD+P. Eight drug pairs, including some popular recommendations like aripiprazole/sertraline, showed higher than average scores which suggest their potential in treating AD+P via strong synergetic effects. Our proposed combinations of antipsychotic and antidepressant therapy showed a strong superiority over current antipsychotics treatment for AD+P. The observed beneficial effects can be further strengthened by optimizing drug‐pair selection based on our systems pharmacology analysis.
Procyanidin B2 regulates the Sirt1/Nrf2 signaling pathway to improve random‐pattern skin flap survival
Authors: Li Yao , Zhu Yurun , Hu Fei , Liu Lue , Shen Guangjie , Tu Qiming 
Published: May 2023

AbstractRandom‐pattern skin flaps have been widely used in the reconstruction of damaged tissues. Ischemia–reperfusion injury occurring in the distal regions of the flap is a common issue, which often leads to flap necrosis and restricts its clinical applications. Procyanidin B2 (PB2), a naturally occurring flavonoid in large quantities in various fruits, has been demonstrated to exhibit several significant pharmacological properties. However, the effect of PB2 on flap viability is not clearly known. Here, using Western blot analysis, immunohistochemistry, and immunofluorescence staining, we observed that PB2 significantly reduced oxidative stress and inflammation and enhanced angiogenesis. Mechanically, we provided evidence for the first time that the beneficial effects of PB2 occur through the activation of the Sirt1/Nrf2 signaling pathway. Moreover, co‐administration of PB2 and EX527, a selective inhibitor of Sirt1, resulted in down‐regulation of the expression of Sirt1, Nrf2, and downstream antioxidants. In summary, our study showed that PB2 might be a novel therapeutic strategy for improving the survival of random‐pattern skin flaps.
As simple as possible but not simpler: structural sensitivity testing of a dynamic model of adolescent overweight and obesity
Authors: Romanenko Eduard , Homer Jack , Lien Nanna 
Published: May 2023

AbstractWe recently published results from an SD model of adolescent overweight and obesity using data from 31 European countries that participate in the Health Behavior in School‐Aged Children (HBSC) study. During model development, we sought to identify a feedback structure with high explanatory power that avoided speculative relationships. Expert reviewers generally agreed with our modeling decisions, but two decisions did raise questions: (1) excluding the influences of food environment and built environment, for which HBSC provided no data; and (2) including five causal links that were supported statistically but might be considered disputable. To address the reviewers' questions, we created four possible model structures and performed automated calibration followed by intervention testing and ranking. We then compared the goodness‐of‐fit and intervention results. We discuss implications for how to move forward with the model, including through additional data gathering. © 2023 The Authors. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society.
iAMY‐DC: Identifying Amyloid Proteins by Using Dynamic Correlation Features
Authors: Zou Hongliang 
Published: May 2023

AbstractRecent studies reported that amyloid proteins keep a closely relationship with some common diseases, such as Alzhemier's disease, Parkinson's disease, and type 2 diabetes. In view of this, it is an urgent task to discriminate amyloid proteins from non‐amyloid proteins. In this work, we developed a new machine learning model to identify amyloid proteins based on the sequence information. Firstly, fifty different kinds of physicochemical (PC) properties were employed to denote sequences. Then, a sliding window approach was adopted to capture the local correlation information based on Pearson's correlation coefficient. And the Least Absolute Shrinkage and Selection Operator (LASSO) algorithm was used to select these most distinguishing features. Given that the number of negative samples larger than the number of positive samples, the popular synthetic minority oversampling technique (SMOTE) algorithm was utilized to solve the unbalanced dataset. Experiments were performed on support vector machine by using jackknife test. Compared with the existing predictors, experimental results showed that the proposed method has significantly improvement in distinguishing amyloid from non‐amyloid proteins. The dataset and codes used in this study were available at https://figshare.com/articles/online_resource/iAMY‐DC/20268093.
Green Synthesis of 2‐Thioxo‐4‐quinazolinone Derivatives in Water
Authors: Makiyama Kouhei , Mimura Yuusuke , Tomotani Yuuki , Tanimori Shinji 
Published: May 2023

AbstractA series of biologically important 3‐substituted‐2‐thixo‐4‐quinazolinones have been synthesized starting from methyl 2‐isothicyanatobenzoate and amines without the use of additives under mild reaction conditions in water. This transformation tolerates a wide range of amines, which include anilines, alkyl amines, and hydrazines, to afford 60 diverse 3‐substituted‐2‐thixo‐4‐quinazolinones including 34 new compounds at 60 °C for 30 min in good yields. This method avoids the use of organic solvent and the generation of toxic waste to demonstrate a cost efficient, green and sustainable method for the synthesis of 2‐thixo‐4‐quinazolinone derivatives as valuable heterocycles for biological and materials studies.
Unlocking Deep and Fast Potassium‐Ion Storage through Phosphorus Heterostructure
Authors: Zhao Xiaoju , Geng Shitao , Zhou Tong , Wang Yan , Tang Shanshan , Qu Zongtao , Wang Shuo , Zhang Xiao , Xu Qiuchen , Yuan Bin , Ouyang Zhaofeng , Peng Huisheng , Tang Shaochun , Sun Hao 
Published: May 2023

AbstractPotassium‐ion battery represents a promising alternative of conventional lithium‐ion batteries in sustainable and grid‐scale energy storage. Among various anode materials, elemental phosphorus (P) has been actively pursued owing to the ideal natural abundance, theoretical capacity, and electrode potential. However, the sluggish redox kinetics of elemental P has hindered fast and deep potassiation process toward the formation of final potassiation product (K3P), which leads to inferior reversible capacity and rate performance. Here, it is shown that rational design on black/red P heterostructure can significantly improve K‐ion adsorption, injection and immigration, thus for the first time unlocking K3P as the reversible potassiation product for elemental P anodes. Density functional theory calculations reveal the fast adsorption and diffusion kinetics of K‐ion at the heterostructure interface, which delivers a highly reversible specific capacity of 923 mAh g−1 at 0.05 A g−1, excellent rate capability (335 mAh g−1 at 1 A g−1), and cycling performance (83.3% capacity retention at 0.8 A g−1 after 300 cycles). These results can unlock other sluggish and irreversible battery chemistries toward sustainable and high‐performing energy storage.