bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mineral magnetic variation of the minle loess/palaeosol sequence of the late glacial to holocene period in the northeastern Tibetan Plateau
Authors: Xiong Jianguo , Zhong Yuezhi , Liu Caicai , Liu Qingri , Zhang Huiping , Deng Chenglong , Li Youli 
Published: July 2023

SUMMARY
Located at the modern junction of the Asian Summer Monsoon and the Westerlies, the northeastern Tibetan Plateau and western Chinese Loess Plateau are in distinct climatic setting from the middle and eastern Chinese Loess Plateau. Besides, Holocene climate variations near the Asian Summer Monsoon margin are highly debated with different models proposed. We carried out environmental magnetic analyses on the Minle loess section, with continuous deposition between 13.3–0.5 ka, located near this margin. Results show that the magnetic susceptibilities of palaeosols are dominantly contributed by superparamagnetic (SP) and single-domain (SD) maghemite and/or magnetite produced by pedogenesis. Limited changes in the content of haematite indicate that dust origin hardly influenced the magnetic mineral variations. The section is divided into four substages according to the changes in magnetic indices and provides a full scene of Holocene climatic evolutions. During the coldest and driest Late Glacial (13.3–11.7 ka), it displays the weakest pedogenesis, as suggested by the lowest SP and SD concentration. The strongest pedogenesis in the Minle section produced higher magnetic susceptibility than the loess records in the Chinese Loess Plateau during the early Holocene Optimum (11.7–8.1 ka). The subsequently declined summer insolation, equatorward migrated Westerlies and the weakened Asian Summer Monsoon led to weak pedogenesis during the middle Holocene (8.1–5.3 ka). Stronger pedogenesis during the late Holocene (5.3–0.5 ka) than the middle Holocene might be due to lower evapotranspiration from weaker insolation and/or to the enhanced winter Westerlies. We attribute the spatiotemporal differences in climatic records of the Chinese loess to precipitation, effective humidity and aeolian geomorphological processes.
Galectin-12 modulates Kupffer cell polarization to alter the progression of nonalcoholic fatty liver disease
Authors: Lee Jyun-Lin , Wang Yao-Chien , Hsu Yu-An , Chen Chih-Sheng , Weng Rui-Cian , Lu Yen-Pei , Chuang Chun-Yu , Wan Lei 
Published: July 2023

Abstract
Nonalcoholic fatty liver disease is caused by an imbalance in lipid metabolism and immune response to pose a risk factor for liver fibrosis. Recent evidence indicates that M2 macrophages secrete transforming growth factor-β1, which contributes to liver fibrosis. Galectin-12 has been demonstrated to regulate lipid metabolism and macrophage polarization. The purpose of this study is to investigate the role of galectin-12 in the development of nonalcoholic fatty liver disease and fibrosis. Liver tissue from wild-type C57BL/6 mice fed with a high-fat diet containing cholesterol and cholic acid for 4–12 weeks was used to examine galectin-12 expression and its correlation with nonalcoholic fatty liver disease. Furthermore, the effects of galectin-12 on M2 macrophages during the progression of nonalcoholic fatty liver disease were investigated by studying Kupffer cells from galectin-12 knockout mice and doxycycline-inducible Gal12−/–THP-1 cells. Ablation of galectin-12 promoted M2 polarization of Kupffer cells, as indicated by higher levels of M2 markers, such as arginase I and chitinase 3-like protein 3. Furthermore, the activation of signal transducer and activator of transcription 6 was significantly higher in Gal12−/− macrophages activated by interleukin-4, which was correlated with higher levels of transforming growth factor-β1. Moreover, Gal12−/− macrophage-conditioned medium promoted hepatic stellate cells myofibroblast differentiation, which was indicated by higher α-smooth muscle actin expression levels compared with those treated with LacZ control medium. Finally, we demonstrated that galectin-12 knockdown negatively regulated the suppressor of cytokine signaling 3 levels. These findings suggested that galectin-12 balances M1/M2 polarization of Kupffer cells to prevent nonalcoholic fatty liver disease progression.
Systematic Review and Meta-Analysis of the Use of Serum Leucine-Rich Alpha-2 Glycoprotein to Assess Crohn’s Disease Activity
Authors: Okita Muneyori , Nakashima Keita , Yamamura Takeshi , Matsui Shigeyuki 
Published: July 2023

Abstract

Background
Although fecal calprotectin is the most widely used biomarker for assessing Crohn’s disease activity, serum leucine-rich alpha-2 glycoprotein has recently attracted attention, especially in Japan. Here we performed a systematic review and meta-analysis of serum leucine-rich alpha-2 glycoprotein to obtain evidence for its accuracy in assessing Crohn’s disease activity.

Methods
On February 1, 2023, we performed searches of PubMed, Web of Science, and CENTRAL. The Prospero number is CRD42023396034. The primary outcomes were the sensitivity and specificity of serum leucine-rich alpha-2 glycoprotein for assessing Crohn’s disease activity. We used a bivariate generalized linear mixed model, assuming a binomial distribution at the test level and a bivariate normal distribution at the between-test level.

Results
We selected 9 studies involving 797 individuals in our systematic review. Regarding the primary outcomes, the synthesized sensitivity and specificity of serum leucine-rich alpha-2 glycoprotein were 77.0% (95% confidence interval, 67.8% to 84.2%) and 81.1% (95% confidence interval, 72.6% to 87.4%), respectively. The area under the curve was 0.86, and the partial area under the curve was 0.78. Regarding between-study heterogeneity, both the I2 value by Zhou and Dendukuri approach and the I2 value by Holling sample size–adjusted approaches were 0%.

Conclusions
Our systematic review and meta-analysis of serum leucine-rich alpha-2 glycoprotein demonstrated its accuracy in assessing Crohn’s disease activity. Further studies are needed to demonstrate its clinical utility and clinical validity.
What Do We Know about How Armed Conflict Affects Social Cohesion? A Review of the Empirical Literature
Authors: Fiedler Charlotte 
Published: July 2023

Abstract
How does armed conflict affect the social fabric of societies? This question is central if we want to understand better why some countries experience repeated cycles of violence. In recent years, considerable scientific work has been put into studying the social legacies of armed conflict. This article brings these academic studies together in a novel way, taking a holistic perspective and analyzing each of the three constituent elements of social cohesion—trust, cooperation, and identity—in detail and along both a vertical (state–society relations) and a horizontal (interpersonal and intergroup relations) dimension. Bringing together insights from fifty empirical studies, I call into question the initial optimism expressed by some scholars that conflict increases social cohesion. Only political participation seems to often be positively affected by experiencing conflict. In contrast, social and political trust as well as identification and cooperation across groups declines. However, research in several of these sub-elements of social cohesion is still nascent so that the strengths and shortcomings of the different studies are discussed and future avenues for research are identified.
The nuclear lamina is required for proper development and nuclear shape distortion in tomato
Authors: Blunt Endia L , Choi Junsik , Sussman Hayley , Christopherson Rachel C , Keen Patricia , Rahmati Ishka Maryam , Li Linda Y , Idrovo Joanna M , Julkowska Magdalena M , Van Eck Joyce , Richards Eric J 
Published: July 2023

Abstract
The nuclear lamina in plant cells is composed of plant-specific proteins, including nuclear matrix constituent proteins (NMCPs), which have been postulated to be functional analogs of lamin proteins that provide structural integrity to the organelle and help stabilize the three-dimensional organization of the genome. Using genomic editing, we generated alleles for the three genes encoding NMCPs in cultivated tomato (Solanum lycopersicum) to determine if the consequences of perturbing the nuclear lamina in this crop species were similar to or distinct from those observed in the model Arabidopsis thaliana. Loss of the sole NMCP2-class protein was lethal in tomato but is tolerated in Arabidopsis. Moreover, depletion of NMCP1-type nuclear lamina proteins leads to distinct developmental phenotypes in tomato, including leaf morphology defects and reduced root growth rate (in nmcp1b mutants), compared with cognate mutants in Arabidopsis. These findings suggest that the nuclear lamina interfaces with different developmental and signaling pathways in tomato compared with Arabidopsis. At the subcellular level, however, tomato nmcp mutants resembled their Arabidopsis counterparts in displaying smaller and more spherical nuclei in differentiated cells. This result argues that the plant nuclear lamina facilitates nuclear shape distortion in response to forces exerted on the organelle within the cell.
We need to talk about Candida tropicalis: Virulence factors and survival mechanisms
Authors: dos Santos Murilo Moreira , Ishida Kelly 
Published: July 2023

Abstract
Candida tropicalis is a notable species of the Candida genus representing an impressive epidemiology in tropical regions, especially in South America and Asia, where India already presents the species as the first in Candida epidemiology. Candida tropicalis has also shown a worrying antifungal resistance profile in recent years. It is essential to highlight that each pathogenic species of the Candida genus has a particular biology; however, Candida virulence factors are almost entirely based on studies with C. albicans. The intrinsic resistance of C. krusei to some azoles, the intrinsic osmotolerance of C. tropicalis, and the multidrug resistance of C. auris are just a few examples of how the biology of each Candida species is unique. Despite being a phylogenetically close species, C. tropicalis can support 15% NaCl, antagonistically metabolize and signal N-acetylglucosamine, encode 16 reported ALS genes, and other specificities discussed here compared to C. albicans. It is essential to clarify the details of the C. tropicalis infectious process, including identifying the participating secreted enzyme(s), the factors responsible for tissue damage, and the mechanisms underlying the morphogenesis and tolerance signaling pathways. In this review, we thoroughly assembled what is known about the main virulence factors of C. tropicalis, highlighting the missing pieces to stimulate further research with C. tropicalis and other non-Candida albicans species.
Identification of the simplest sugar-like molecule glycolaldehyde towards the hot molecular core G358.93–0.03 MM1
Authors: Manna Arijit , Pal Sabyasachi , Viti Serena , Sinha Sekhar 
Published: July 2023

ABSTRACT
Glycolaldehyde (CH2OHCHO) is the simplest monosaccharide sugar in the interstellar medium, and it is directly involved in the origin of life via the ‘RNA world’ hypothesis. We present the first detection of CH2OHCHO towards the hot molecular core G358.93–0.03 MM1 using the Atacama Large Millimetre/Submillimetre Array (ALMA). The calculated column density of CH2OHCHO towards G358.93–0.03 MM1 is (1.52 ± 0.9) × 1016 cm−2 with an excitation temperature of 300 ± 68.5 K. The derived fractional abundance of CH2OHCHO with respect to H2 is (4.90 ± 2.92) × 10−9, which is consistent with that estimated by existing two-phase warm-up chemical models. We discuss the possible formation pathways of CH2OHCHO within the context of hot molecular cores and hot corinos and find that CH2OHCHO is likely formed via the reactions of radical HCO and radical CH2OH on the grain-surface of G358.93–0.03 MM1.
Quasi-periodic eruptions from mildly eccentric unstable mass transfer in galactic nuclei
Authors: Lu Wenbin , Quataert Eliot 
Published: July 2023

ABSTRACT
We propose that the recently observed quasi-periodic eruptions (QPEs) in galactic nuclei are produced by unstable mass transfer due to Roche lobe overflow of a low-mass main-sequence star in a mildly eccentric (e ∼ 0.5) orbit. We argue that the QPE emission is powered by circularization shocks, but not directly by black hole (BH) accretion. Our model predicts the presence of a time-steady accretion disc that is bolometrically brighter than the time-averaged QPE luminosity, but primarily emits in the extreme-ultraviolet. This is consistent with the quiescent soft X-ray emission detected in between the eruptions in eROSITA QPE1, QPE2, and GSN 069. Such accretion discs have an unusual νLν ∝ ν12/7 optical spectrum. The lifetime of the bright QPE phase, 102–103 yr, is set by mass-loss triggered by ram-pressure interaction between the star and the accretion disc fed by the star itself. We show that the stellar orbits needed to explain QPEs can be efficiently created by the Hills breakup of tight stellar binaries provided that (i) the stellar binary orbit is tidally hardened before the breakup due to diffusive growth of the f-mode amplitude and (ii) the captured star’s orbit decays by gravitational wave emission without significant orbital angular momentum diffusion (which is the case for low-mass BHs, MBH ≲ 106 M⊙). We conclude by discussing the implications of our model for hyper-velocity stars, extreme mass ratio inspirals, repeating partial TDEs, and related stellar phenomena in galactic nuclei.
The MillenniumTNG Project: the impact of baryons and massive neutrinos on high-resolution weak gravitational lensing convergence maps
Authors: Ferlito Fulvio , Springel Volker , Davies Christopher T , Hernández-Aguayo César , Pakmor Rüdiger , Barrera Monica , White Simon D M , Delgado Ana Maria , Hadzhiyska Boryana , Hernquist Lars , Kannan Rahul , Bose Sownak , Frenk Carlos 
Published: July 2023

ABSTRACT
We study weak gravitational lensing convergence maps produced from the MillenniumTNG simulations by direct projection of the mass distribution on the past backwards lightcone of a fiducial observer. We explore the lensing maps over a large dynamic range in simulation mass and angular resolution, allowing us to establish a clear assessment of numerical convergence. By comparing full physics hydrodynamical simulations with corresponding dark-matter-only runs, we quantify the impact of baryonic physics on the most important weak lensing statistics. Likewise, we predict the impact of massive neutrinos reliably far into the non-linear regime. We also demonstrate that the ‘fixed & paired’ variance suppression technique increases the statistical robustness of the simulation predictions on large scales not only for time slices but also for continuously output lightcone data. We find that both baryonic and neutrino effects substantially impact weak lensing shear measurements, with the latter dominating over the former on large angular scales. Thus, both effects must explicitly be included to obtain sufficiently accurate predictions for stage IV lensing surveys. Reassuringly, our results agree accurately with other simulation results where available, supporting the promise of simulation modelling for precision cosmology far into the non-linear regime.
Towards a full wCDM map-based analysis for weak lensing surveys
Authors: Zürcher D , Fluri J , Ajani V , Fischbacher S , Refregier A , Kacprzak T 
Published: July 2023

ABSTRACT
The next generation of weak lensing surveys will measure the matter distribution of the local universe with unprecedented precision, allowing the resolution of non-Gaussian features of the convergence field. This encourages the use of higher-order mass-map statistics for cosmological parameter inference. We extend the forward-modelling based methodology introduced in a previous forecast paper to match these new requirements. We provide multiple forecasts for the $w$CDM parameter constraints that can be expected from stage 3 and 4 weak lensing surveys. We consider different survey setups, summary statistics and mass map filters including wavelets. We take into account the shear bias, photometric redshift uncertainties, and intrinsic alignment. The impact of baryons is investigated and the necessary scale cuts are applied. We compare the angular power spectrum analysis to peak and minima counts as well as Minkowski functionals of the mass maps. We find a preference for Starlet over Gaussian filters. Our results suggest that using a survey setup with 10 instead of 5 tomographic redshift bins is beneficial. Adding cross-tomographic information improves the constraints on cosmology and especially on galaxy intrinsic alignment for all statistics. In terms of constraining power, we find the angular power spectrum and the peak counts to be equally matched for stage 4 surveys, followed by minima counts and the Minkowski functionals. Combining different summary statistics significantly improves the constraints and compensates the stringent scale cuts. We identify the most ‘cost-effective’ combination to be the angular power spectrum, peak counts and Minkowski functionals following Starlet filtering.
The complex spectral behavior of the newly discovered neutron star X-ray binary Swift J1858.6-0814
Authors: Mondal Aditya S , Raychaudhuri B , Dewangan G C 
Published: July 2023

ABSTRACT
We report on the NuSTAR observation of the newly discovered neutron star X-ray binary Swift J1858.6-0814 taken on 23rd March 2019. The light curve of the source exhibits several large flares during some time intervals of this observation. The source is softer in the high-intensity interval where the large flaring activity mainly occurs. We perform time-resolved spectroscopy on the source by extracting spectra for two different intensity intervals. The source was observed with a 3 − 79keV luminosity of ∼9.68 × 1036 ergs/s and ∼4.78 × 1036 ergs/s for high and low-intensity interval, respectively assuming a distance of 15 kpc. We find a large value of the absorbing column density ($\rm {N_{H}}\sim 1.1\times 10^{23}$ cm−2), and it appears to be uncorrelated with the observed flux of the source. Each spectrum shows evidence of Fe Kα emission in the 5 − 7keV energy band, an absorption edge around ∼7 − 8keV, and a broad Compton hump above 15keV, indicating the presence of a reflection spectrum. The observed features are well explained by the contribution of a relativistic reflection model and a partially covering absorption model. From the best-fit spectral model, we found an inner disc radius to be $4.87_{-0.96}^{+1.63}\,\,R_{ISCO}$ (for the high-intensity interval) and $5.68_{-2.78}^{+9.54}\,\,R_{ISCO}$ (for the low-intensity interval), indicating a significant disc truncation. The disk inclination is found to be relatively low, i &lt; 330. We further place an upper limit on this source’s magnetic field strength considering the disc is truncated at the magnetospheric radius.
Detection of a strong ~2.5 Hz modulation in the newly discovered millisecond pulsar MAXI J1816–195
Authors: Li P P , Tao L , Zhang L , Bu Q C , Qu J L , Ji L , Wang P J , Chen Y P , Zhang S , Ma R C , Yang Z X , Ye W T , Zhao S J , Zhao Q C , Huang Y , Ma X , Qiao E L , Jia S M , Zhang S N 
Published: July 2023

ABSTRACT
MAXI J1816–195 is a newly discovered accreting millisecond X-ray pulsar that went outburst in 2022 June. Through timing analysis with Neutron star Interior Composition Explorer (NICER) and Nuclear Spectroscopic Telescope Array (NuSTAR) observations, we find a transient modulation at ~2.5 Hz during the decay period of MAXI J1816–195. The modulation is strongly correlated with a spectral hardening, and its fractional rms amplitude increases with energy. These results suggest that the modulation is likely to be produced in an unstable corona. In addition, the presence of the modulation during thermonuclear bursts indicates that it may originate from a disc-corona where the optical depth is likely the main factor affecting the modulation, rather than temperature. Moreover, we find significant reflection features in the spectra observed simultaneously by NICER and NuSTAR, including a relativistically broadened Fe-K line around 6–7 keV, and a Compton hump in the 10–30 keV energy band. The radius of the inner disc is constrained to be Rin = (1.04–1.23) RISCO based on reflection modeling of the broad-band spectra. Assuming that the inner disc is truncated at the magnetosphere radius, we estimate that the magnetic field strength is $\le 4.67 \times 10^{8}\, \rm G$.
Ton S 415: a close binary containing an intermediate helium subdwarf discovered with SALT and TESS
Authors: Snowdon E J , Jeffery C S , Schlagenhauf S , Dorsch M , Monageng I M 
Published: July 2023

ABSTRACT
Hot subdwarfs are early-type low-mass stars lying between the main sequence and the white dwarf sequence. The majority have helium-burning cores and helium-poor surfaces. A minority have helium-rich surfaces. A few, including Ton S 415, have surfaces with between 10 per cent and 90 per cent helium (by number). Their properties are diverse and their origins mostly unknown. Ton S 415 was identified as a suspected binary in a Southern African Large Telescope (SALT) survey of hot subdwarfs from its large radial velocity. Using SALT spectroscopy and Transiting Exoplanet Survey Satellite light curves, we confirm that Ton S 415 is a close binary with an orbital period $p=84.6460\pm 0.0004\, {\rm min}$ and velocity semi-amplitude $K=175.5\pm 1.0\, {\rm km\, s^{-1}}$. Analysis of the SALT spectrum and broad-band spectral energy distribution shows the visible star to have an effective temperature $T_{\rm eff}=43\, 300\pm 1000\, {\rm K}$, surface gravity $\log g/{\rm cm\, s^{-2}}=5.89\pm 0.10$, surface helium-to-hydrogen ratio log y = −0.62 ± 0.10, radius $R=0.1074\pm 0.0025\, R_{\odot }$, and mass $M=0.33\pm 0.09\, {\rm {\rm M}_{\odot }}$. By modelling the light curve, we estimate the binary mass ratio to be q = 0.7 ± 0.3 and infer an unseen white dwarf companion with a mass of $M_{\rm WD}=0.47\pm 0.24\, {\rm {\rm M}_{\odot }}$. The results are consistent with a post-common-envelope binary that lost its hydrogen envelope before reaching the peak of the red giant branch, becoming a hot subdwarf with a non-canonical mass. We predict that the system will evolve into a double white dwarf binary before eventually either forming a stably accreting AM CVn system, or merging to form an R CrB star.
The energy distribution of the first supernovae
Authors: Koutsouridou I , Salvadori S , Skúladóttir Á , Rossi M , Vanni I , Pagnini G 
Published: July 2023

ABSTRACT
The nature of the first Pop III stars is still a mystery and the energy distribution of the first supernovae is completely unexplored. For the first time we account simultaneously for the unknown initial mass function (IMF), stellar mixing, and energy distribution function (EDF) of Pop III stars in the context of a cosmological model for the formation of a MW-analogue. Our data-calibrated semi-analytic model is based on a N-body simulation and follows the formation and evolution of both Pop III and Pop II/I stars in their proper time-scales. We discover degeneracies between the adopted Pop III unknowns, in the predicted metallicity and carbonicity distribution functions and the fraction of C-enhanced stars. None the less, we are able to provide the first available constraints on the EDF, $dN/dE_\star \propto E_{\star }^{-\alpha _e}$ with 1 ≤ αe ≤ 2.5. In addition, the characteristic mass of the Pop III IMF should be mch &lt; 100 M⊙, assuming a mass range consistent with hydrodynamical simulations (0.1–1000 M⊙). Independent of the assumed Pop III properties, we find that all $\rm [C/Fe]\gt +0.7$ stars (with $\rm [Fe/H]\lt -2.8$) have been enriched by Pop III supernovae at a $\gt 20~{{\ \rm per\ cent}}$ level, and all $\rm [C/Fe]\gt +2$ stars at a $\gt 95~{{\ \rm per\ cent}}$ level. All very metal-poor stars with $\rm [C/Fe]\lt 0$ are predicted to be predominantly enriched by Pop III hypernovae and/or pair instability supernovae. To better constrain the primordial EDF, it is absolutely crucial to have a complete and accurate determination of the metallicity distribution function, and the properties of C-enhanced metal-poor stars (frequency and [C/Fe]) in the Galactic halo.