bluuebunny/crossref_metadata_2025_split huggingface dataset:
SPOPL induces tumorigenicity and stemness in glioma stem cells by activating Notch signaling
Authors: hu tianyu , Xuan Ruoheng , Han Erqiao , Cai Lingshan , Xia Zhibo 
Published: June 2023

Abstract
Glioma stem cells (GSCs) have been associated with high heterogeneity, recurrence rate, and resistance to radiotherapy and chemotherapy of glioblastoma multiforme (GBM). As members of the Meprin-associated Traf homology (MATH) - Broad-complex, Tramtrack, and Bric-a-brac (BTB) protein family, both SPOPL and SPOP have been associated with cancer stem cells in various tumors. Although it has been established that SPOPL has a broader expression profile than SPOP in the human brain, whether it plays an important role in GSCs remains unclear. In the present study, analysis of SPOPL expression in GSCs, glioma cell lines, and GBM clinical specimens showed that high SPOPL expression correlated with poor prognosis. Analysis of the biological function of SPOPL in GSCs showed that SPOPL promotes the proliferation, tumorigenic and self-renewal ability of GSCs and inhibits the differentiation potential of GSCs. RNA-seq revealed that SPOPL could affect the biological functions of GSCs through activation of the Notch signaling pathway. Overall, SPOPL represents a possible molecular target for GBM treatment.
Novel Flower Pencil-Like ZnO/myristic acid composite: synthesis, characterization and study of their hydrophobic surfaces
Authors: Al-Mulla Ban Hamdan , Nawabjan Amirjan , Abdulelah Haider , Hussin Siti Maherah 
Published: June 2023

Abstract
Nanoflower pencil-like ZnO (diameter 20-24nm) with hexagonal structure was synthesized by sol-gel method. By altering ZnO nanoflower with a myristic acid (MA) that has low surface energy, a composite coating material known as MA-ZnO was successfully fabricated. For the first time, MA was coated on the surface of ZnO nanoflower to create composite coating and it has been confirmed that the shorter-chain MA acid can offer a denser coating on the nanoflower surface compared to other coating with similar volume, which induced super-hydrophobic effect. Different wt% of MA was prepared and mixed with ZnO. The surface morphology, crystalline structure, FTIR, and PL properties of each MA-ZnO composite thin films were investigated. The highest water contact angle (WCA) shown by the composite coating is 164.5º, increment of 90% in comparison to pure ZnO, which proved its super-hydrophobicity.
Role of Gross Domestic Expenditure on Research and Development (GERD)On Economic GDP A Time Series Forecasting Approach Using ARIMA Model
Authors: Hasan Zeba , Alam M.Afshar , Kaur Harleen , Khan Ihtiram Raza , Alankar Bhavya 
Published: June 2023

Abstract

Research and development is recognized as one of the important factors in sustainable development goals (SDG − 9) to build resilient infrastructure, promote sustainable industrialization and foster innovation. The global Expenditure on Research and Development (GERD) is one of the essentially derived indicators. Research and Development of any country is pretentiously affected by the sincere contribution of global expenditure on research and development (GERD) and number of the researchers in R&D employed in research activities. It is known that the innovation index is the measure of any country’s global expenditure on research and development (GERD) and its contribution to developmental research, along with its support in other contributive factors of the innovation index. To support this kind of index-based study limited data is present nowadays which is not supportive of the design of policy scenarios and technology development models. For the sake of data assessment, machine learning is nowadays playing a crucial role, and therefore in this paper we have studied various machine learning models but henceforth used the ARIMA model to study the impact of data variables and its time series forecasting. In our study, a comprehensive R&D spending estimate and its correlation with other variables reveal that the midst of the global GERD shuffle has to be re-formed to escalate profound domestic research in elaborated terms.
Therapies in patients with persistent postural-perceptual dizziness: Challenges and Elections: A Systematic review
Authors: Castillo-Bustamante Melissa , García Alejandro , Candelo Estephania , Zamorano Alicia Amairan Gutiérrez , Escobar Luisa , Sánchez Juan , Espinoza Ireri , Briceño Omarliv , Andalón-Dueñas Elizabeth , Madrigal Jorge 
Published: June 2023

Abstract
Introduction:
Postural persistent perceptual dizziness (PPPD) is a chronic vestibular disorder consisting of unsteadiness, and non-spinning vertigo lasting for 3 months, exacerbated by upright posture, active or passive motion of self, and moving visual stimuli. Medical therapy, Cognitive Behavioral Therapy (CBT), and Vestibular Rehabilitation (VR) is frequently used in patients with this disorder, however, the indications for each one, still being controversial. Our goal was to gain a deeper understanding of the existing PPPD treatments and how they affected the quality of life and other factors related to the condition's progress
Methods:
A systematic review was conducted between July and September 2022, based on PRISMA guidelines. Mean age, the proportion of patients using Medical Therapy, Cognitive Behavioral Therapy, and Vestibular Rehabilitation, Dizziness Handicap Inventory Scores and Scores associated with anxiety (HADS and HARS), depression, Safety Behavioral Inventory, Dizziness Symptoms Inventory, and Vertigo Severity Score
Results:
41 studies were reviewed and 14 of them met the inclusion criteria for the systematic review. Dizziness Handicap Inventory showed lower scores using VR and CBT. On the physical and functional dizziness handicap inventory using Medical Therapy, lower scores were typically observed. With the use of CBT, the Dizziness Severity Inventory and Safety Behavioral Scores decreased.
Discussion:
Targeted PPPD therapies may contribute to the patient’s symptom improvement and better quality of life. Based on the available data, healthcare providers should think about tailoring PPPD treatments.
Racism against migrants in healthcare in Europe: a scoping review
Authors: Pattillo Mia , Stieglitz Sigsten , Angoumis Konstantinos , Gottlieb Nora 
Published: June 2023

Abstract
Background
Racial discrimination is frequently mentioned as a social determinant of migrants’ health and a barrier to healthcare. However, in the European context, racial discrimination and its impact on migrants’ access to care is remarkably under-researched. This scoping review makes a first step toward filling this void by mapping the existing literature on racism against migrants in healthcare in Europe, identifying evidence gaps, and offering recommendations for future research.
Methods
Following PRISMA guidelines, four databases were searched for empirical studies published in English between 1992 and 2022. Studies were included if they report on manifestations, experiences and/or impacts of racism against migrants in a healthcare setting in a European country. Findings were summarized by study characteristics (geographical scope, study design, research question and measures) and thematically (manifestations and experience of racism, and impacts of racism on healthcare).
Results
Out of 2365 initial hits, 1724 records were included in the title/abstract-screening, 87 records in the full text-screening, and 43 records in the data extraction. For many country and healthcare contexts, evidence on racism in healthcare is lacking. Most study apply an explorative qualitative research design; comparability and generalizability of research results are low. Our analysis furthermore shows a near-exclusive research focus on racism on the interpersonal level as compared to institutional and structural levels. Our synthesis of study results identifies three interrelated ways in which racism manifests in and impacts migrants’ healthcare: 1) general anti-migration bias, 2) health- and healthcare-related prejudice, and 3) differential medical treatment.
Conclusions
Our review underscores how racism reinforces inequities in healthcare access, healthcare quality, and health outcomes for racialized migrants. It also highlights the need for more research on racism in healthcare across a greater scope of country contexts, healthcare settings and migrant/racialized communities in order to understand specific forms of discrimination and capture race as a context-contingent social construct. Methods and insights from other disciplines may help to critically examine categories and hierarchies in light of underlying historical, sociopolitical and socioeconomic processes and structures. It is critical for future research to consider individual-level racism as embedded in racism on institutional and structural levels.
Ethnomycological Survey of Wild Mushroom Species Utilized by the Subanen Tribes in Selected Barangays in Tangub City, Misamis Occidental, Philippines
Authors: Despe Airene , Plimaco Sheila Marie Y. , Japos March Ivan , Niez Luigi 
Published: June 2023

Abstract
Since prehistoric times, ethnic cultures have used wild mushrooms as food and medicine. Despite the extensive use of these important resources in ethnomycology, little is known about them, and the documentation that does exist is insufficient. The goal of the current study was to record the traditional knowledge of the Subanen populations regarding the use of different types of wild mushrooms. Field walks to collect the indicated mushroom species were undertaken after an actual interview utilizing a semi-structured questionnaire. To support diverse therapeutic claims, the local name, specific usage, method of preparation, and range of uses for wild mushrooms are described. In the ten barangays of Matugnaw, Uwayan, Sicot, Paiton, Taguite, Katagan, Kimat, Baluc, Salimpuno, and Caniangan, the study discovered various naturally occurring mushrooms. Leaf litter, soil, and rotting logs were used to identify the ten different mushroom species. Termitomyces cartilaginous, Auricularia auricularia-judae, Volvariella volvacea, Schizophyllum commune, Auricularia polytricha, Ganoderma applanatum, Trametes polyzona, Pycnoporus sanguineus, Trametes elegans and Lenzites betulinus were the species of wild mushrooms that the Subanen tribe used for food and medicine, respectively. These precious mushrooms were used by some ethnic tribes in the Philippines and other nations as well, and their broad use may support their therapeutic claims.
Consumo alimentar, estado nutricional e nível de atividade física de mulheres idosas praticantes de exercício físico
Authors: SILVA Amanda Karine da , FERNANDES Dalila Pinto de Souza , SILVA Isabella Antonia Soares da , CARNEIRO-JÚNIOR Miguel Araujo , DELLA LUCIA Ceres Mattos , RIBEIRO Andréia Queiroz 
Published: June 2023

Objetivou-se avaliar o consumo alimentar, estado nutricional e nível de atividade física de mulheres idosas praticantes de exercício físico. O estudo é parte de um projeto de extensão voltado para atividade física para pessoas idosas. Foram analisados, além do consumo alimentar, o nível de atividade física, estado nutricional e adiposidade corporal de 45 mulheres. A média de idade das participantes foi de 67,8 anos (DP=6,04). Um elevado percentual (57,8%) estava com excesso de peso e 87,8% apresentaram elevada adiposidade, indicando risco de doenças associadas à obesidade. Observou-se consumo inadequado de gorduras monoinsaturadas, cálcio e vitamina B6. As elevadas frequências de excesso de peso, adiposidade elevada e inadequações do consumo alimentar observadas, evidenciam a importância de intervenções nutricionais associadas à prática de atividade física, na direção de um cuidado integral à saúde das pessoas idosas para melhor qualidade de vida dessa população.
Filosofia literaria y teorìa mimètica
Authors: Ballen Rodriguez Juan Sebastian 
Published: June 2023

Una de las novedades de la teoría mimética consiste en su mirada particular sobre el deseo humano y de sus despliegues en el campo de la literatura, asunto que ha sido materia de estudio por la filosofía, la antropología y la fenomenología. Buscamos a continuación explorar desde los insumos teóricos que se mencionan esbozar algunas ideas sobre la filosofía literaria y cómo estos mismo pueden ser brújula para orientar el lector en el estudio e interpretación de una obra literaria del canon nacional: La Vorágine de José Eustasio Rivera.
¿En qué radica la novedad del planteamiento filosófico que se ha formulado en el presente ensayo? Básicamente en mostrar que la teoría mimética deriva en una filosofía literaria, que conecta con un análisis fenomenológico a propósito de cómo surge la violencia social a la luz de la expresión literaria.
Para llevar a cabo dicho cometido, la propuesto se desglosa de la siguiente manera: en primer lugar, se propone una idea de lo que se entiende por filosofía literaria en relación con la apuesta del pensamiento de René Girard. Hecho esto, se procede a tematizar las relaciones entre fenomenología y teoría mimética en donde se profundiza en el análisis filosófico de los conceptos de la experiencia, el otro, la rivalidad, la vida y el deseo y la relación que guardan con la literatura. En un tercer momento, se propone el análisis filosófico que en clave mimética se aplica a la novela La Voràgine del escritor huilense José Eustasio Rivera.
Finalmente, se propone en las conclusiones otros acercamientos a la teoría del deseo mimético y sus vínculos con el estudio filosófico de la literatura, de cara a la dialéctica del reconocimiento y sus intérpretes contemporáneos según la postura girardiana.
Relanzamiento feminista del legado de Ignacio Ellacuría: repensar «los pobres» desde una perspectiva teológica interseccional
Authors: Azcuy Virginia R. 
Published: June 2023

Esta presentación se propone revisitar el legado teológico de Ignacio Ellacuría sobre «los pobres» y sugerir algunas claves bíblico-teológicas para su relanzamiento feminista. En cuanto al pensamiento del autor, en el marco de su soteriología histórica, se recupera su distinción fundamental entre pobres socio-económicos y pobres «con espíritu», su relación con el mensaje de las bienaventuranzas y la actualidad eclesial de su pensamiento. En vistas a un relanzamiento feminista del aporte ellacuriano, se retoman algunos estudios bíblicos de autoras como Elsa Tamez, sobre Agar (cf. Gn 16 y 21,8-21) e Ivoni Richter Reimer, sobre Isabel y María (cf. Lc 1,24-25 y 1,39-56). Estos textos se vinculan por tratar sobre mujeres que sufren, en cuanto tales, pobreza-opresión-humillación y son liberadas-bendecidas-exaltadas por la acción de Dios. Ellos muestran vidas de mujeres marcadas por una trama de opresión y una espiritualidad transformadora. El Magnificat, canto de una mujer humillada y exaltada, resume sin duda esa pobreza «con espíritu» que anticipa la llegada del Reino. En la reflexión final, se busca repensar a «los pobres» desde una perspectiva teológica interseccional, para mostrar la mutua imbricación entre las opresiones de género, clase, etnia y sexualidad. El uso de este enfoque permite ampliar la comprensión teológica de los pobres y desafía el lenguaje en un sentido inclusivo, todo lo cual favorece la visibilidad de la matriz de opresión padecida por las mujeres y el reconocimiento de su acción en procesos de resistencia, liberación y «espiritualización».
Validación de la Escala de estrés percibido por COVID-19 en estudiantes universitarios peruanos
Authors: Ticahuanca Mullo Niria , Chura Quispe Gilber 
Published: June 2023

Resumen
El objetivo de este estudio fue validar y estudiar el desempeño psicométrico, consistencia interna y dimensionalidad de la Escala de Estrés Percibido relacionada con el COVID-19 (EEP-10-C) con una muestra de un total 306 estudiantes, quienes completaron la encuesta voluntariamente. La validez se determinó mediante un análisis factorial confirmatorio y su estructura interna fue calculada con los coeficientes de Alfa de Cronbach y omega de McDonald's. Se realizó un análisis factorial exploratoria y confirmatoria. Los resultados mostraron que la EEP-10-C tenía un coeficiente alfa de Cronbach de 0.859 y omega de McDonald 0.887. Se establecieron dos dimensiones; el distrés general que explicó el 44.2% de varianza y la capacidad de afrontamiento el 55.8% de la varianza acumulada. El AFC de la propuesta bidimensional señalo adecuados índices de ajuste (X2/gl= 2.590, GFI=0.949, TLI=0.936, CFI= 0.952 el SRMR=0.0435 y el RMSEA=0,068) El EEP-10-C tuvo una consistencia interna aceptable y dos dimensiones que desarrollaron el instrumento psicométrico de estrés percibido por covid-19 aceptables para estudiantes universitarios peruanos.
Palabras clave: Estrés percibido, Psicológico, Estudiantes, Educación, Covid-19, Pandemia, Análisis factorial, Estadística, Estudios de validación.
The Role of BUMDesma in Improving The Economy of The Community of Sekaran District, Lamongan
Authors: Karimah Alfiyatul , Sulistiyono Herry 
Published: June 2023

The purpose of this study is to identify and analyze the efforts of the BUMDesma Sekar Mandiri in achieving its goals and the impact of the BUMDesma for the people of Sekaran sub-district, especially those involved in BUMDesma activities. In this study, the author uses a qualitative case study method. Data collection techniques in this study were interviews and documentation. The results of the study describe two active business units, namely Lembaga Keuangan Desa and marketing of sub-district superior products, the benefits obtained by the people involved such as social funds, IPTW, training. Several problems were analyzed through the perspective of contract theory. So that produces some suggestions. The limitation of this study lies in the focus of research which only discusses the profile, the mechanism, and the impact of BUMDesma from the point of view
institutional economics. This research is expected to be able to become a consideration to determine the right strategy in an effort to improve
community welfare through empowerment.
Study of malachite green dye biosorption on acerola (Malpighia emarginata) seeds for the treatment of coloured wastewater: kinetics, equilibrium, and experimental design
Authors: Gadelha Antonio José Ferreira , da Rocha Clarice Oliveira , do Nascimento Marcelo Rodrigues , Rocha Luellen Pereira , de Sousa David Aragão , da Cunha Bernardo Vale 
Published: June 2023

Abstract

In this work, malachite green dye was removed from an aqueous effluent using acerola seed as an adsorbent. The adsorbent was characterized by Fourier transform infrared (FTIR), X-ray diffraction, zero charge potential, and acid group concentration techniques. The findings revealed that the adsorbent has a characteristic composition of lignocellulosic materials, as described by the FTIR data, besides having a pH-PZC of 3.5 and a concentration of acid groups of 0.2313 mmol g−1. The central composite design was used for batch experiments, and the effects of three variables were analysed. The optimum conditions (pH, particle size, and adsorbent mass) were 10.0, 600 μm, and 0.8 g, respectively, for 97.52% dye removal. Redlich–Peterson isotherm fitted well to the experimental data (R2 = 0.997 and root-mean-square error (RMSE) = 1.168). From the Langmuir isotherm, the maximum adsorption capacity obtained for dye was 103.50 mg g−1. As for the adsorption kinetics, it was found that the pseudo-second-order model sufficiently describes the experimental data (R2 = 0.999 and RMSE = 0.018). Thus, the acerola seed has excellent properties as an adsorbent, demonstrating a remarkable performance and a great capacity to be used in the treatment of aqueous effluents contaminated by dyes.
Removal of fluoride and pathogens from water using the combined electrocoagulation-inline-electrolytic disinfection process
Authors: Njau Oscar Ezekiel , Otter Philipp , Machunda Revocatus , Rugaika Anita , Wydra Kerstin , Njau Karoli Nicholas 
Published: June 2023

Abstract

The consecutive removal of fluoride (defluoridation) and pathogens (disinfection) in drinking water through combined electrocoagulation-inline-electrolytic disinfection (EC–ECl2) process with aluminum and dimension-stable mixed oxide electrodes was reported in this study. Laboratory trials were conducted on the effects of flow rate, initial pH, current density, and supporting electrolytes for defluoridation and disinfection processes. The results have shown that with a flow rate of 10 L/h, initial pH of 6, the current density of 9.4 mA/cm2 (EC cell) and 3.1 mA/cm2 (ECl2 cell), supporting electrolyte concentration of 165 mg/L, and electrolysis time of 50 min, a defluoridation rate of 88% (initial concentration of 12.3 mg/L) and complete disinfection (initial fecal coliforms of 19,700 colony-forming units per 100 mL (CFU/100 mL)) can be reached. The final concentration of fluoride and pathogens in treated water was 1.44 mg/L and 0 CFU/100 mL, which are within the acceptable limit of the World Health Organization and the Tanzania Bureau of Standards of 1.5 mg/L and 0 CFU/100 mL, respectively. The EC–ECl2 system is a promising approach for consecutive defluoridation and disinfection of water to save millions from fluorosis and waterborne diseases. However, optimization potential with regard to energetic efficiency and system complexity was identified.
BibPat: Quantum K-means Clustering with Incremental Enhancement
Authors: Deshmukh Shradha , Mulay Preeti 
Published: June 2023

Background:
One of the main areas of study within the broader paradigm of quantum machine learning
is quantum clustering (QC). Considering the potential time and cost savings that solutions to realworld
issues employing QC algorithms bring, in comparison to their classical methods, researchers
have recently developed a keen interest in QC. With new algorithms and their applications being
invented virtually every other day, this is still a highly young and fascinating area of research. Based
on the background information provided, this work aims to analyze research and patent databases
spanning twelve years (2010 to mid-2022) to identify and understand the publishing and patent
trends in the field of QC. This study aims to study the topological analyses, important study areas,
relationships, and collaboration patterns that distinguish traditional and developing research clusters.
The graphical representation of the progress of publications and patents over time depends on such
rigorous field mapping. This paper presents a comprehensive list of all the sources through the network,
bibliometric and patentometric (BibPat) analysis, and future research scope in the QC. The
top authors, universities, and research fields were listed after the primary and secondary keywords
connected to the quantum K-means clustering algorithm in the analysis design. Reviewing the articles
and then delving into the specifics of the patents will help us evaluate the total body of work on
the quantum K-means clustering technique. Using the thorough BibPat tools and numerous research
and patent databases like Scopus, IEEE, ACM, Google Scholar, Lens, Google Patents, and
Espacenet, the analysis design displays the patents and journal papers that have been published. Additionally,
it is crucial for later research because it aids in the identification of areas for current research
interests and possible avenues for future study. QC offers various studies in disciplines from
computer science to psychology. The Ministry of Education, China, produced most publications.
Since 2014, the trend has been up, and experts continue studying the issue. The BibPat analysis
shows that the Chinese National Natural Science Foundation has facilitated funding for cutting-edge
research. In order to open the door for future research and investigation on the substantial amount of
unstructured real-time data, the report concluded by proposing an incremental QC approach.