bluuebunny/crossref_metadata_2025_split huggingface dataset:
Portable Impedance-Sensing Device for Microorganism Characterization in the Field
Authors: Bouzid Karim , Greener Jesse , Carrara Sandro , Gosselin Benoit 
Published: April 2023

Abstract
A variety of biosensors have been proposed to quickly detect and measure the properties of individual microorganisms among heterogeneous populations, but challenges related to cost, portability, stability, sensitivity, and power consumption limit their applicability. This study proposes a portable microfluidic device based on impedance flow-cytometry and electrical impedance spectroscopy that can detect and quantify the size of microparticles larger than 45 μm, such as algae and microplastics. The system is low cost ($300), portable (5 cm × 5 cm), low-power (1.2 W), and easily fabricated utilizing a 3D-printer and industrial printed circuit board technology. The main novelty we demonstrate is the use of square wave excitation signal for impedance measurements with quadrature phase-sensitive detectors. A linked algorithm removes the errors associated to higher order harmonics. After validating the performance of the device for complex impedance models, we used it to detect and differentiate between polyethylene microbeads of sizes between 63 μm and 83 μm, and buccal cells between 45 μm and 70 μm. A precision of 3% is reported for the measured impedance and a minimum size of 45 μm is reported for the particle characterization.
Experience of treating congenital complete atrioventricular block with epicardial pacemaker in infants and young children:a retrospective study
Authors: Song Linhong , Meng Qiang , Liu Changgen , Wang Gang , Wang Hui , Zhou Gengxu , Feng Zhichun 
Published: April 2023

Abstract
Background This article summarizes the treatment experience for congenital complete atrioventricular block (CCHB) in newborns and infants, and discusses the necessity and feasibility of treating CCHB with permanent pacemaker implantation in this population.
Methods In this study, the clinical data and follow-up results of nine children admitted at our center with CCHB from January 2005 to March 2023 were retrospectively analyzed. Among them, two children received early implantation of permanent pacemakers (within 1 year of age), two children received non-early implantation (1 year or older), and the remaining five children received no pacemaker implantation. CCHB diagnosis was confirmed by clinical symptoms and clinical examinations, including electrocardiography and echocardiography before surgery. After surgery, the pacing and sensing functions of the pacemaker were observed using electrocardiography, echocardiography, and pacing threshold monitoring. A comprehensive evaluation of the treatment effect was performed, taking into account improvements in clinical symptoms, growth and development, and the absence of any other potential complications. The children who did not receive pacemaker implantation were followed up.
Results Among the four children who successfully received pacemaker implantation, one child who received non-early implantation died. For the remaining three children, the threshold level, amplitude, impedance, and minute ventilation sensor function of the pacemaker were good during the follow-up period, with a heart rate at the pacing rate. Their development followed the percentile curve, and their motor and cognitive development were not affected. Among the children who did not receive pacemaker implantation, two died and three were lost to follow-up.
Conclusions Early implantation of an epicardial pacemaker in newborns and infants diagnosed with CCHB can significantly improve clinical symptoms without affecting their growth and development. In this study, we have determined that permanent pacemaker implantation is necessary for these children because the treatment plan's safety, feasibility, and favorable prognosis.
Increasing rectum–prostate distance using a hydrogel spacer to reduce radiation exposure during proton beam therapy for prostate cancer
Authors: Narukawa Tsukasa , Aibe Norihiro , Tsujimoto Masashi , Shiraishi Takumi , Kimoto Takuya , Suzuki Gen , Ueda Takashi , Fujihara Atsuko , Yamazaki Hideya , Ukimura Osamu 
Published: April 2023

Abstract
SpaceOAR®, a polyethylene-glycol hydrogel, reduces rectal radiation exposure during radiation therapy for prostate cancer. This study aimed to investigate the impact of our modified technique of hydrogel insertion, which achieves greater separated distance at prostate-apex, on radiation exposure reduction during proton beam therapy (PBT). We included 330 patients undergoing PBT with the relative biological effectiveness (RBE) of 63 Gray (Gy) for localized prostate cancer, and categorized them into groups 0 (no spacer, n = 141), 1 (separated distance of spacer at the prostate-apex level < 7.5 mm, n = 81), and 2 (distance ≥ 7.5 mm, n = 108). The rectal volumes to receive 30–60 Gy (RBE), was estimated and described as Rectal V30–60 (ml). The Rectal V30–60 (ml) was significantly lower in group 2 than in group 1, and in group 1 than in group 0. After propensity score matching, the multivariate logistic regression analysis revealed that the most significant factor to reduce radiation exposure was our modified technique of hydrogel insertion. Therefore, using a hydrogel spacer to expand the prostate–rectum distance not only at prostate-mid to prostate-base level but also at the prostate-apex level can reduce the radiation exposure in PBT for prostate cancer.
The construction of Bert fusion model of speech recognition and sensing for South China electricity charge service scenario
Authors: Wu Guangcai , Zheng Yinglong 
Published: April 2023

Abstract
Electric charge service and management is an important part of electric power work. The effective recovery of electric charge relates to the smooth development of daily work and continuous improvement of operation and management of power supply enterprises. With the large-scale implementation of the card prepayment system, the problem of electricity customers defaulting on electricity charges has been solved to a large extent, but some large electricity users still fail to pay electricity charges on time. Therefore, under the current situation of power grid development, it is still necessary to strengthen the service and management of electricity charges to promote efficient recovery of electricity charges. Speech recognition technology has increasingly become the focus of research institutions at home and abroad. People are committed to enabling machines to understand human speech instructions, and hope to control the machine through speech. The research and development of speech recognition will greatly facilitate people's life in the near future. At present, the development of 5G technology and the proposal of 6G technology make the interconnection of all things not only a hope but also a reality. To realize the interconnection of all things, one of the key technical breakthroughs is the development of a new human-computer interaction sensing system. Under the guidance of relevant theories and methods, this paper systematically analyzes the user structure, electricity charge recovery management and service system, existing problems and causes in South China, and clarifies the necessity of design and application of electricity charge service system in South China power supply companies. The experimental data and empirical analysis results show that the optimized Bert fusion model can provide more digital support for the power supply companies in South China in terms of electricity charge recovery efficiency, management level system improvement and electricity charge service.
English Speaking as a Second Language for Health Sciences’ Undergraduates: Preferred Activities &amp; Motivators
Authors: Jayasinghe Manori , Liyanage Lakeesha , Wijesekara Kanchana , Kotapola Imendra 
Published: April 2023

Abstract
Introduction
Fluency in speaking English as a second language is critical for non-natives in Allied Health Sciences. Unfortunately, the undergraduates who study for health sciences degrees in English medium of instruction still find it challenging. This has made the faculty administration deliver numerous programs to enhance oral skills, which often fail due to poor turnout. The lack of motivation and reluctance to practice are two reasons visible on the surface. Identifying ways to enhance learner motivation has been considered a key challenge in the present study. The types of activities students were interested in have been examined and reported.
Methods
A cross-sectional survey was conducted among the undergraduates in the Pharmacy, Nursing, and Medical Laboratory Science programs. Data were gathered using a self-prepared, validated, self-administered online survey questionnaire that was pilot tested for reliability using 10% (n=21) of the minimum sample size. Cronbach's Alpha values appeared ˃ 0.7. The data analysis was done using SPSS version 20.0. The distinction between intrinsic and extrinsic motivators and demotivators was examined using a paired sample t-test.
Results
There were 277 responses from Pharmacy (33.2%, n=92), Nursing (45.8%, n=127), and MLS (20.9%, n=58). Intrinsic motivation factors had a significant effect (p<0.001, 95% CI) on speaking skills compared to extrinsic motivation factors. Mean intrinsic motivation and mean extrinsic motivation were 4.16 (n=277, SD=0.66) and 3.73 (n=277, SD=0.81), respectively. The mean intrinsic demotivation, 3.16 (n=277, SD=0.77), and mean extrinsic demotivation, 2.56 (n=277, SD=0.91) also showed a significant variation. Findings denoted that students prefer free, relaxing learning experiences over compulsory English-speaking programs.
Conclusions
The results signified that self-motivation was the primary source of inspiration. It is essential that faculty revisit the compulsory and authoritative program designs to realign them, considering the students' motivation and interests at the center of it.
Evaluation of calcification distribution by CT-based textural analysis for discrimination of immature teratoma
Authors: Nakamori Akari , Tsuyoshi Hideaki , Tsujikawa Tetsuya , Orisaka Makoto , Kurokawa Tetsuji , Yoshida Yoshio 
Published: April 2023

Abstract
Background Mature and immature teratomas are differentiated based on tumor markers and calcification or fat distribution. However, no study has objectively quantified the differences in calcification and fat distributions between these tumors. This study aimed to evaluate the diagnostic potential of CT-based textural analysis in differentiating between mature and immature teratomas in patients aged < 20 years.Materials and methods Thirty-two patients with pathologically proven mature cystic (n = 28) and immature teratomas (n = 4) underwent transabdominal ultrasound and/or abdominal and pelvic CT before surgery. The diagnostic performance of CT for assessing imaging features, including subjective manual measurement and objective textural analysis of fat and calcification distributions in the tumors, was evaluated by two experienced readers. The histopathological results were used as the gold standard. The Mann–Whitney U test and receiver operating characteristic curve were used for statistical analysis.Results We evaluated 32 patients (mean age, 14.5 years; age range, 6–19 years). The mean maximum diameter and number of calcifications of immature teratomas were significantly larger than those of mature cystic teratomas (p < 0.01). The mean number of fats of immature teratomas was significantly larger than that of mature cystic teratomas (p < 0.01); however, no significant difference in the maximum diameter of fats was observed. CT textural features for calcification distribution in the tumors showed that mature cystic teratomas had higher homogeneity and energy than immature teratomas. However, immature teratomas showed higher correlation, entropy, and dissimilarity than mature cystic teratomas among features derived from the gray-level co-occurrence matrix (GLCM) (p < 0.05). No significant differences were observed in the CT features of fats derived from GLCM.Conclusion Our results demonstrate that calcification distribution on CT is a potential diagnostic biomarker to discriminate mature from immature teratomas, thus enabling optimal therapeutic selection for patients aged < 20 years.
Identification of novel ferroptosis biomarkers predicts the prognosis of hepatocellular carcinoma
Authors: Wu Siqian , Liu Meiliang , Xiao Suyang , Lai Mingshaung , Wei Liling , Li Deyuan , Wang Lijun , Zeng Xiaoyun , Yin Fuqiang 
Published: April 2023

Abstract
Background: Ferroptosis is a newly recognized type of programmed cell death. This work aimed to explore unreported ferroptosis-related genes that have not been found to predict the prognosis of HCC;
Methods: Candidate genes involved in the prognosis of HCC were identified from CROEMINE and FerrDb. Kaplan-Meier survival and Cox regression analysis were applied to assess the association of single gene and gene combinations with overall survival time (OS) and disease-free survival time (DFS) in TCGA cohort. Additionally, the predictor was further validated in the ICGC cohort. Real-time quantitative polymerase chain reaction (RT-qPCR) and immunohistochemistry were performed in HCC samples.
Results: A total of 719 genes were included. Of these identified genes, 21 and 15 genes can predict OS and DFS, respectively, which had not been reported before. Survival analysis showed elevated mRNA expression of GLMP, SLC38A6, and WDR76 were associated with poor prognosis and three genes combination signature was an independent prognostic factor in HCC. RT-qPCR and Immunohistochemistry confirmed the results;
Conclusions: We established a novel computational process based on big data text-mining and bioinformatics analysis to explore new biomarkers of HCC associated with ferroptosis. Furthermore, after experimentally verified our result, we suggest that the expression of GLMP, SLC38A6, and WDR76 may be used as potential ferroptosis-related biomarkers to evaluate the prognosis of patients with HCC.
‘A recipe for cultural disaster!’– a case study of Woolworths Group’s proposal to build an alcohol megastore in Darwin, Northern Territory
Authors: Crocetti Alessandro Connor , (Larrakia) Beau Cubillo , Yorta) Troy Walker (Yorta , (Mununjali) Fiona Mitchell , (Wakaya) Yin Paradies , Backholer Kathryn , Browne Jennifer 
Published: April 2023

Abstract
Background: The health and wellbeing impacts of commercial activity on Indigenous populations is an emerging field of research. The alcohol industry is a key driver of health and social harms within Australia. In 2016 Woolworths, the largest food and beverage retailer in Australia, proposed to build a Dan Murphy’s alcohol megastore store in Darwin, near three ‘dry’ Aboriginal communities. This study examines the tactics used by Woolworths to advance the Dan Murphy’s proposal and understand how civil society action can overcome powerful commercial interests to protect Aboriginal and Torres Strait Islander health and wellbeing.
Methods: Data from 11 interviews with Aboriginal and non-Aboriginal informants were combined with data extracted from media articles and government, non-government and industry documents. Reflexive thematic analysis was informed by an adapted corporate health impact assessment framework.
Results: Woolworths employed several strategies including lobbying, political pressure, litigation, and divisive public rhetoric, while ignoring the evidence suggesting the store would increase alcohol-related harm. The advocacy campaign against the proposal highlighted the importance of Aboriginal and non-Aboriginal groups working together to counter commercial interests and the need to champion Aboriginal leadership. Advocacy strategies included elevating the voices of community Elders in the media and corporate activism via Woolworths’ investors.
Conclusions: The strategies used by the coalition of Aboriginal and non-Aboriginal groups may be useful in future advocacy campaigns to safeguard Aboriginal and Torres Strait Islander health and wellbeing from commercial interests.
Hydrothermal synthesis of the CeO 2 nanoparticles and its calcination temperature effect on dielectric and supercapacitor performance
Authors: Godlaveeti Sreenivasa Kumar , Chintaparty Rajababu , Somala Adinarayana Reddy , Nagireddy Ramamanohar Reddy 
Published: April 2023

Abstract
Cerium oxide (CeO2) nanoparticles (NPs) was synthesized by the hydrothermal method. In this method cerium (IV) sulfate tetrahydrate as precursor was taken as solvent and sodium hydroxide as a precipitating agent. In this case, the CeO2 NPs prepared at dried and different calcination temperature conditions and followed by characterized by different instrument techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), High resolution transmission electron microscopy (HR-TEM), Energy dispersive X-ray analysis (EDAX) and Raman spectroscopy were employed to examine the crystal structure, functional groups, morphology and elemental composition of the final product. The dried and different calcination of the CeO2 NPs were investigated by supercapacitor and dielectric performance.
Predictive Ability of Complete Blood Count, Mean Platelet Ratio, Mean Platelet Volume, and Neutrophil/Lymphocyte Ratio for Severe Pneumonia among RT-PCR or Radiologically Proven COVID-19 Patients
Authors: Bohra Harishkumar Rameshkumar , Bhaskaan P , Rehana V , Nivedita A , Lakra P , Raghav P , Tandon A 
Published: April 2023

Abstract

In Rajasthan, the picture of COVID-19 has been very gloomy and on 21st December 2020 there were 12,422 active cases, and 283,957 cumulative cases which included either discharged or cured or migrated to other places. Disease may start with milder clinical manifestation, but it may suddenly progress to acute respiratory failure or acute respiratory distress syndrome or septic shock or metabolic acidosis or coagulopathies. There is an association of neutrophil/lymphocyte ratio (NLR), Mean Platelet Volume (MPV), Mean Platelet Ratio (MPR) and with the progression of the COVID-19 infection and it can be utilized by the physicians for identification of high risk or deteriorating patients at an early stage. In the context of this background, the present study was undertaken to study the predictive ability of these hematological parameters (especially MPV, MPR, NLR) in progression of COVID-19 infection to severe pneumonia among RT-PCR or radiologically proven COVID-19 patients. Materials and method: Analytical cross sectional Hospital based study of 729 COVID-19 patients enrolled between 1st April 2020 to 30th Nov 2021 conducted in Bangur hospital of Pali district, Rajasthan. Socio-demographic information, clinical profile, investigation reports and clinical outcome were collected from the electronic medical records. WHO’s definition for severe pneumonia of COVID-19 (17) was utilized to categorize patients with severe pneumonia. Data was entered in Microsoft Excel and checked for errors. The analyses were done using Jamovi and SPSS v.23.0. Results: It was found that neutrophil/lymphocyte ratio was significantly higher among those participants with evere pneumonia, but there was no such significance appreciated for mean platelet ratio.. Parameters related to acute infection (Total WBC count, granulocyte (%), absolute granulocyte count) were directly correlated with N/L ratio and Mean Platelet ratio (except granulocyte (%)).From multivariable analysis, it was found that increase in N/L ratio and decrease in albumin were significant predictors of severe pneumonia. Conclusion: N/L ratio is good predictor marker of COVID 19 severe pneumonia. MPV, MPR, and PC are nit the good predictive markers of COVID 19 severe pneumonia.
Effect of the level of alveolar atrophy on implant placement accuracy in guided surgery for full-arch restorations supported by four implants: An in vitro study
Authors: Göçmen Gökhan , Bayrakçıoğlu Ahmet , Bayram Ferit 
Published: April 2023

Abstract
Background
Fixed screw-retained full-arch restoration supported by four implants is a popular treatment option for edentulous arches. Optimal alignment of implants is quite challenging in extremely atrophied edentulous cases, and a small amount of deviation is expected during guided surgery. This study aimed to compare implant accuracy among edentulous jaws with various levels of atrophy.
Methods
Five separate copies of each Cawood model (III–V) were produced for the maxilla and mandible. A total of 120 implants were placed (30 models). The implant accuracy was assessed based on angular deviations at the base (angle, 3D offset, distal, vestibular, and apical) and tip (3D offset, distal, vestibular, and apical).
Results
The atrophy level of the jaws had a statistically significant effect on deviation; implants showed greater deviation from the planned location as the atrophy level increased.
Conclusion
Given that implant deviation increased with the degree of atrophy, a greater safety margin from important anatomical structures is recommended when planning implant location for guided surgery in Cawood V cases.
Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages
Authors: D'Amato Rocco , Taxiarchi Chrysanthi , Galardini Marco , Trusso Alessandro , Minuz Roxana , Grilli Silvia , Somerville Alastair , Shittu Dammy , Khalil Ahmad , Galizi Roberto , Crisanti Andrea , Müller Ruth , Simoni Alekos 
Published: April 2023

Abstract
CRISPR-based gene drives have the potential to spread within a population and are considered as promising vector control tools. A doublesex-targeting gene drive was shown effective to suppress laboratory populations in both small and large cages, and it is considered for field application. Challenges related to the field-use of gene drives and the evolving regulatory framework demand for systems able to modulate or revert the action of gene drives, as part of post-release risk-mitigation plans. We developed an improved AcrIIA4-based anti-drive strain and showed inhibition of gene drive spread, in complex feeding and reproductive behavioural conditions. A stochastic model predicted the experimentally-observed genotypes dynamics in overlapping generations in medium- and large-sized cages and further demonstrated the effectiveness of anti-drive in different release and fitness scenarios. This study provides a further validation for the use of anti-drive system in controlling the spread of gene drive in Anopheles under complex behavioural conditions.
Comparative Studies of Decoupling Schemes in the Current Control Loop of Three-Phase Drives at Extreme Stator/Sampling Frequency Ratios
Authors: Nuß Uwe 
Published: April 2023

Abstract
In this paper, the performance of different continuous-time and discrete-time models of the electrical subsystem of induction machines and permanent-magnet synchronous machines as well as methods based on them for decoupling the direct and quadrature axis components of the stator current are investigated and compared. The focus here is on inverter-fed, pulse width modulated drives when operated with a relatively large product of stator frequency and sampling time, where significant differences between the models and decoupling methods used come to light. Recommendations for a discrete-time model to be used uniformly in the future are made, as well as statements on whether feedforward or feedback decoupling structures are better suited. Simulation studies and measurement results support the statements made above.