bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regional integration and public healthcare environment: Evidence from China
Authors: Tu Chenglin , Zeng Yonghui , Long Hongyu , Yu Chenyang , Tan Yuanfang , Zhou Yu , Zang Chuanxiang 
Published: January 2023

IntroductionExisting studies have focused on the impact of economic development and urban expansion on public healthcare environment but has ignored the importance of regional integration. Regional integration reflects the spatial distribution of the labor force, which significantly affects healthcare workforce and healthcare infrastructure development.MethodsBased on panel nested data for 137 cities in 16 major city clusters in China from 2001 to 2019, this paper assesses the impact of regional integration on the public healthcare environment through a hierarchical linear model (HLM).ResultsOur findings indicate that a 1% increase in regional integration leads to a 6.6 and 1.9% improvement in healthcare workforce and healthcare infrastructure. The results of the mechanism analysis indicate that regional integration affects the public healthcare environment through improving transportation infrastructure and industrial upgrading. In addition, regional integration has a stronger effect on cities with lower levels of economic development and healthcare environments. Finally, the endogeneity test based on the difference-in-difference (DID) model and the robustness test based on high-dimensional fixed effects model conduct the consistent conclusions.DiscussionPolicies to improve the public healthcare environment through promoting regional integration are proposed. Government should develop a more comprehensive regional cooperation plan to improve the public healthcare environment. Also, financial spending on improving the healthcare environment in peripheral cities should be increased. In addition, regional integration policy development needs to consider differences across regions.
Subjective attitudes moderate the social connectedness in esports gaming during COVID-19 pandemic: A cross-sectional study
Authors: Shan Dan , Xu Jilai , Liu Tongyu , Zhang Yanyi , Dai Ziyun , Zheng Yuandian , Liu Chang , Wei Yuanning , Dai Zhihao 
Published: January 2023

BackgroundElectronic sports (esports) has become a practical intervention for young people craving social connections since the COVID-19 pandemic. Past studies have shown an equivocal role of esports participation in boosting social ties or social connectedness. It is unclear if their relationship is affected by subjective attitudes of gamers. Moreover, the present COVID-19 pandemic may further modify this relationship to a greater extent.ObjectiveThis study primarily aimed to investigate the moderating effect of participants' subjective attitudes toward esports gaming on the relationship between in-game interaction during esports participation and participants' anticipated social connectedness among Chinese young adults during the COVID-19 lockdown periods in China.MethodsWe conducted a nationwide online questionnaire survey through the Credamo platform among 550 Chinese young adults in the present study. The Social Connectedness Scale-Revised was used to assess participants' social connectedness levels.ResultsFour hundred and fifty-three participants were included in the final analysis. The effective response rate was 82.4%. Our results showed that the esports participation measured by in-game communication frequency among participants, as an independent factor, was negatively associated with participants' social connectedness scores (β = −0.13, p &lt; 0.05). However, when the moderating effect of subjective attitudes toward esports gaming was considered, the association between communication frequency and social connectedness scores was turned into the opposite direction with a larger effect size (β = 0.35, p &lt; 0.001).ConclusionOur primary finding revealed that a positive mindset in esports gaming is indispensable in boosting social connectedness. Overall, our study provided supporting evidence for the benefits of esports on individuals' social connectedness. In future circumstances similar to the COVID-19 era, playing esports games is strongly encouraged in an attempt to maintain social connections and relieve psychological stress. In the meantime, we believe that having a positive esports experience, often associated with a positive mindset during gaming, can better promote social connectedness. Nevertheless, the amount of time spent on gaming per day should be of great concern, as esports games can be addictive, especially for teenagers and college students.
Prevalence and predictors of psychological assistance services for older individuals in Turkish society
Authors: Coşkun Hüseyin , Yildiz Ibrahim , Alkan Ömer 
Published: January 2023

Background/aimDue to the high contribution of psychological problems to the decline in the comfortable lifestyle of the older individuals, determining the factors that affect individuals' receiving psychological services and searching for solutions based on these factors is one of the primary concerns of national and international decision-makers. This study aimed to identify the factors that affect older individuals' access to psychological assistance services in Turkey.MethodsIn this study, the Turkish Health Research micro dataset, which was conducted by the Turkish Statistical Institute (TURKSTAT) in 2016 and 2019, was employed. In this dataset, the data of 7,252 older individuals were analyzed. Using binary logistic analysis, the factors that are effective for obtaining psychological assistance for the older individuals were identified.ResultsAccording to the results of the analysis, factors such as gender, education, general health status, disease status, payment of health expenditures, and body mass index affected older individuals who received psychological assistance.ConclusionIn recent years, there has been a rise in the availability of psychological assistance services for the older individuals. By identifying factors that increase the likelihood of receiving psychological assistance services, this study is expected to contribute to the creation and regulation of psychological assistance services to prevent possible psychological problems that may occur in old age, minimize the problems experienced by individuals, and promote a more comfortable lifestyle.
Health utility of children with acute lymphoblastic leukemia in China
Authors: Wang Wei , Dong Yaqi , Ji Mingjing , Zhang Xiaoyan , Cai Jiaoyang 
Published: January 2023

BackgroundAcute lymphoblastic leukemia is the most common cancer in children. As the 5-year survival rate has been improved to over 80%, more emphasis is now placed on reducing therapy toxicities and enhancing health-related quality of life (HRQoL) of patients during treatment. Our objective was to measure health utility of pediatric acute lymphoblastic leukemia (pALL) patients in China, examine utility weights of different treatment phases and influencing factors of health utility, as well as identify which aspects of HRQoL were most impaired.MethodsA cross-sectional study was conducted in Shanghai Children's Medical Center (SCMC) Affiliated to Shanghai Jiao Tong University School of Medicine in China from April to November 2021. Primary caregivers of 247 patients completed the assessment by CHU9D-CHN and health utility scores were computed for all the patients and stratified by treatment phases. Various multivariable models were constructed and the best was chosen to identify independent factors associated with utility scores. Factors affecting the most impaired dimensions were also examined.ResultsThe overall mean (SD) health utility score was 0.79 (±0.17) and significantly increased from induction (0.73 [±0.19], P &lt; 0.001) to consolidation (0.74 [±0.18]), and to maintenance (0.82 [±0.16]). After adjusting for potentially influencing factors, utility scores in induction (Beta = −0.086, P = 0.005) and consolidation (Beta = −0.074, P = 0.043) were constantly lower than those during maintenance. In item-level analysis, lower age and induction phase were found to be significantly associated with high severity reported on the “school work/homework” dimension. Additionally, only the induction phase (vs. maintenance, OR = 2.24, P = 0.016) was independently associated with the high severity level reported on the “able to join in activities” dimension.ConclusionsThis is the first study that measured health utility of children with pALL in China. Mean health utility scores increased from induction to maintenance. These provided important utility estimates that help inform future health economic models. The phrasing of “School work/homework” in CHU9D-CHN could be further improved. More efforts are needed to design and implement specific interventions targeting at the dimension “able to join in activities” for enhancing HRQoL of children with pALL in China.
The mixed layer modified radionuclide atmospheric diffusion based on Gaussian model
Authors: Li Ting , Zheng Xiaolei , Yu Shengpeng , Wang Jin , Cheng Jie , Liu Jie 
Published: January 2023

BackgroundAtmospheric diffusion is often accompanied by complex meteorological conditions of inversion temperature.MethodsIn response to the emergency needs for rapid consequence assessment of nuclear accidents under these complex meteorological conditions, a Gaussian diffusion-based model of radionuclide is developed with mixed layer modification. The inhibition effect of the inversion temperature on the diffusion of radionuclides is modified in the vertical direction. The intensity of the radionuclide source is modified by the decay constant.ResultsThe results indicate that the enhancement effect of the mixed layer on the concentration of radionuclides is reflected. The shorter the half-life of the radionuclide, the greater the effect of reducing the diffusion concentration. The Kincaid dataset validation in the Model Validation Kit (MVK) shows that, compared to the non-modified model, predictions of the modified model have an enhancement effect beyond 5 km, modulating the prediction values to be closer to the observation values.ConclusionsThis development is consistent with the modification effects of the mixed layer. The statistical indicators show that the criteria of the modified model meet the criteria of the recommended model.
Attending live sporting events predicts subjective wellbeing and reduces loneliness
Authors: Keyes Helen , Gradidge Sarah , Gibson Nicola , Harvey Annelie , Roeloffs Shyanne , Zawisza Magdalena , Forwood Suzanna 
Published: January 2023

IntroductionThis study explored whether attending live sporting events (LSEs) improved subjective wellbeing and loneliness, above and beyond demographic predictors.MethodsSecondary data from 7,249 adults from the Taking Part 2019–20 survey (UK household survey of participation in culture and sport) were analyzed. Multiple linear regressions captured the effect of attending LSEs (yes/no) on wellbeing variables (happiness, anxiety, a sense that life is worthwhile and life satisfaction) and loneliness, with gender, Index of Multiple Deprivation (IMD), age group, health and employment as covariates.ResultsFor life satisfaction, a sense that life is worthwhile, and loneliness, inclusion of LSE attendance in the model improved model fit significantly, although ΔR2 values were small (ΔR2 = 0.001–0.003). For happiness and anxiety, the inclusion of LSE attendance did not alter model fit. LSE attendance was associated with increased life satisfaction (b = 0.171, p &lt; 0.001), a greater sense of life being worthwhile (b = 0.230, p &lt; 0.001), and reduced loneliness (b = −0.083, p &lt; 0.01).ConclusionLSE attendance has positive associations with some aspects of subjective wellbeing (life satisfaction and a sense of life being worthwhile) and loneliness, above and beyond demographic predictors. Whilst the variance explained is small, it is comparable to demographic predictors (e.g., being in employment). As even small-sized differences in SWB can have meaningful outcomes (e.g., for mortality), we conclude that LSE attendance may still offer a scalable, accessible and effective means of improving the public's wellbeing and reducing loneliness.
A prospective evaluation of breast thermography enhanced by a novel machine learning technique for screening breast abnormalities in a general population of women presenting to a secondary care hospital
Authors: Bansal Richa , Collison Sathiakar , Krishnan Lakshmi , Aggarwal Bharat , Vidyasagar Mathukumalli , Kakileti Siva Teja , Manjunath Geetha 
Published: January 2023

ObjectiveArtificial intelligence-enhanced breast thermography is being evaluated as an ancillary modality in the evaluation of breast disease. The objective of this study was to evaluate the clinical performance of Thermalytix, a CE-marked, AI-based thermal imaging test, with respect to conventional mammography.MethodsA prospective, comparative study performed between 15 December 2018 and 06 January 2020 evaluated the performance of Thermalytix in 459 women with both dense and nondense breast tissue. Both symptomatic and asymptomatic women, aged 30–80 years, presenting to the hospital underwent Thermalytix followed by 2-D mammography and appropriate confirmatory investigations to confirm malignancy. The radiologist interpreting the mammograms and the technician using the Thermalytix tool were blinded to the others' findings. The statistical analysis was performed by a third party.ResultsA total of 687 women were recruited, of whom 459 fulfilled the inclusion criteria. Twenty-one malignancies were detected (21/459, 4.6%). The overall sensitivity of Thermalytix was 95.24% (95% CI, 76.18–99.88), and the specificity was 88.58% (95% CI, 85.23–91.41). In women with dense breasts (n = 168, 36.6%), the sensitivity was 100% (95% CI, 69.15–100), and the specificity was 81.65% (95% CI, 74.72–87.35). Among these 168 women, 37 women (22%) were reported as BI-RADS 0 on mammography; in this subset, the sensitivity of Thermalytix was 100% (95% CI, 69.15–100), and the specificity was 77.22% (95% CI, 69.88–83.50).ConclusionThermalytix showed acceptable sensitivity and specificity with respect to mammography in the overall patient population. Thermalytix outperformed mammography in women with dense breasts and those reported as BI-RADS 0.
Cropping systems and agricultural management strategies affect soil organic carbon dynamics in semi-arid regions
Authors: Gorooei Aram , Aynehband Amir , Rahnama Afrasyab , Gaiser Thomas , Kamali Bahareh 
Published: January 2023

IntroductionSoil organic carbon (SOC) dynamic is one of the important factors that directly influence soil properties and quality. In agro-ecosystems, the SOC dynamics are strongly linked to agricultural management practices.MethodsIn this study, we investigated the response of SOC and its fractions to various combination of agricultural management practices based on measurements obtained from an experiment conducted over four growing seasons from 2018 to 2020 in Ahvaz, Iran. The experimental treatments involved three agricultural strategies combined with four crop rotation systems. The agricultural strategies comprised conventional (CON: mineral fertilizer, removal of all crop residues), organic (ORG: organic fertilizer, 30% return of crop residues to the soil), and integrated (INT: mineral/organic fertilizer, 15% return of crop residues) strategies. The crop rotation systems were: fallow-wheat (F-W), corn-wheat (C-W), sesame-wheat (S-W), and mung bean-wheat (B-W). Soil samples were collected from all treatments and SOC, labile-C, and non-labile-C were measured.Results and discussionAfter two years of experiment, no significant improvement was found in SOC of CON strategy (p ≤ 0.05). The ORG and INT strategies contained on average 1.1 and 1.06 times more SOC than the CON strategy, respectively. The value of labile-C was decreased during summer cultivations and increased in the soil samples collected after winter cultivations. However, although the quantity of labile-C in ORG (2 g kg−1) was higher than INT (1.83 g kg−1) and CON (1.87 g kg−1) overall during the experiment time, after the second summer cultivation despite the gradual accumulation of organic matter due to high levels of temperature and humidity, the content in ORG reduced to1.47 g kg−1. In all three agricultural management strategies, the SOC content in the four rotation systems was according to the following descending order B-W (5.7 g kg−1) &gt; C-W (5.29 g kg−1) &gt; S-W (5.23 g kg−1) &gt; F-W (4.52 g kg−1). Therefore, for this region M-W and S-W crop rotation systems are recommended in addition to C-W (which is the most common rotation system). However, crop rotation systems were more beneficial for C-sequestration when combined with organic and inorganic fertilization and crop residue incorporation. This study gives promising results for implementing INT and ORG strategies under long-term cropping systems containing various summer crops in rotation with wheat for improving SOC dynamics in semi-arid regions in Iran.
Making a case for just agricultural transformation in the UNFCCC: An analysis of justice in the Koronivia Joint Work on Agriculture
Authors: Sarku Rebecca , Tauzie Mapenzie , Whitfield Stephen 
Published: January 2023

IntroductionFrom 2018 to 2022, the Koronivia Joint Working Group on Agriculture (KJWA) was the key forum for debating global agricultural change and integrating agricultural transformation priorities into the mechanisms of the United Nations Framework Convention on Climate Change (UNFCCC). As a forerunner to the landmark decision at COP27 to initiate the Sharm El-Sheik Joint Work on Implementation of Climate Action on Agriculture and Food Security, it provided an opportunity to further the (as yet underdeveloped) discourse around social transformation and just transformation in agriculture. At the conclusion of this 4 year process, we ask: to what extent and in what ways has a just agricultural transformation been envisioned within the Koronivia Joint Working Group on Agriculture and what are the implications for the Sharm El-Sheik Joint Work on Implementation?MethodsThe paper presents a textual analysis of 155 written submissions, workshops, and concluding statements from across the full programme of KJWA workshops, meetings, and consultations.ResultsWe find that references to just transformations in agriculture within KJWA are largely implicit, but not absent. We argue that justice has been most obvious and evident when it comes to discussion about who is (and where are) the most vulnerable to climate change and variability, and how access to climate smart technologies and information is distributed. Less evident have been discussions about just representation in the governance and visioning of agricultural transformation, and there have been few explicit appeals to address the historical injustices that have shaped agricultural and rural livelihoods in the Global South.DiscussionWe argue that following its conclusion, there is a danger that the outcomes of KJWA become reduced to a focus on the scaling up of a techno-centric vision of agricultural transformation. To counter this, there is need for ongoing dialogue to develop a shared and more complete understanding of justice that should be central to how agricultural transformation is integrated into the UNFCCC. We highlight some recommendations of how a justice agenda could be taken forward under the Sharm El-Sheik Joint Work on Implementation.
Evaluation of the efficacy of a cannabidiol and cannabidiolic acid rich hemp extract for pain in dogs following a tibial plateau leveling osteotomy
Authors: Klatzkow Sarah , Davis Garrett , Shmalberg Justin , Gallastegui Aitor , Miscioscia Erin , Tarricone Jason , Elam Lindsay , Johnson Matthew D. , Leonard Katelyn M. , Wakshlag Joseph J. 
Published: January 2023

ObjectiveTo determine the impact of a cannabidiol (CBD) and cannabidiolic acid (CBDA) rich hemp product on acute post-operative pain in dogs following a tibial plateau leveling osteotomy (TPLO), and to evaluate for changes in early bone healing, serum chemistry profiles, and complete blood counts.MethodsIn this randomized, placebo controlled, blinded clinical trial, 44 client-owned dogs were assigned to receive either a CBD/CBDA product dosed at 2–2.5 mg/kg PO every 12 h or a placebo for 4 weeks following a TPLO. Variables evaluated before (week 0), and at 2 and 4 weeks post-operatively included standardized veterinary assessments for pain score, weight-bearing, and lameness, the Canine Brief Pain Inventory (pain interference score–PIS, pain severity score–PSS), and serum biochemistry. Complete blood counts were performed at weeks 0 and 4. Additionally, orthogonal radiographs evaluating the degree of healing were taken at week 4. A mixed model analysis, analyzing changes of variables of interest from enrollment baseline to all other time points was utilized, with a p-value ≤ 0.05 considered significant.ResultsOf the 44 enrolled patients, 3 were lost to follow up and excluded from analysis. No significant differences were noted between placebo (n = 19) and CBD/CBDA (n = 22) groups at any point in pain score, degree of lameness, degree of weight-bearing, PIS, PSS, or radiographic healing of the osteotomy. A significant finding of elevation of ALP above normal reference range in the treatment group was identified (p = 0.02) and eosinophil count was affected by treatment (p = 0.01), increasing from baseline in placebo and decreasing in treatment groups. Finally, a significant difference (p = 0.03) was noted at 2 weeks post-operatively where 4 patients in the placebo group and no treatment patients received trazodone to facilitate activity restrictions.Clinical significanceUse of a CBD/CBDA rich hemp product dosed at 2–2.5 mg/kg PO every 12 h did not have a significant impact on pain or delay early bone healing. A statistically significant increase in ALP, decrease in eosinophils, and reduced use of trazodone was identified in the treatment group.
Covering the Crisis: Evolution of Key Topics and Actors in COVID-19 News Coverage in Switzerland
Authors: Ort Alexander , Rohrbach Tobias , Diviani Nicola , Rubinelli Sara 
Published: January 2023

Objectives: The goal of this study is to map the share of COVID-related news articles over time, to investigate key subtopics and their evolution throughout the pandemic, and to identify key actors and their relationship with different aspects of the discourse around the pandemic.Methods: This study uses a large-scale automated content analysis to conduct a within-country comparison of news articles (N = 1,171,114) from two language regions of Switzerland during the first 18 months of the pandemic.Results: News media coverage of the pandemic largely mirrors key epidemiological developments in terms of the volume and content of coverage. Key actors in COVID-related reporting tend to be included in news articles that relate to their respective area of expertise.Conclusion: Balanced news coverage of the pandemic facilitates effective dissemination of pandemic-related information by health authorities.