bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physiological and Gene Expression Response of Interspecific Hybrids of Fraxinus mandshurica × Fraxinus americana to MJ or SNP under Drought
Authors: Cao Yang , He Liming , Song Fei , Li Chuanzhou , Ji Qitian , Liu Jianfei , Peng Guangzhou , Li Boyao , Zeng Fansuo , Zhan Yaguang 
Published: June 2023

Drought affects the growth and production of Fraxinus tree species, such as the precious woody plant Fraxinus mandshurica. Based on interspecific hybrid F1 combinations, D110 plants of F. mandshurica × F. americana with strong drought resistance were selected for this study. To further reveal their heterosis mechanism under drought, in this study, an analysis was conducted pertaining to the physiological indexes and gene expression of related key gene changes in materials of 5 yr D110 seedlings and their female and male parental controls (D113 and 4–3) in response to drought, as well as to the addition of sodium nitrate (SNP, a donor of nitric oxide) and methyl jasmonate (MJ, a donor of jasmonate) signal molecules after drought. The results showed that under drought stress, hybrid D110 plants performed significantly better than their parents, especially compared to D113, in plant growth (the plant height growth was 29.48% higher), photosynthesis (the net photosynthetic rate was 38.4% higher), peroxidation (the increase in MDA content was 71.77% lower), defense enzyme activity (SOD and POD activities were 36.63% and 65.58% higher), hormone contents (ABA, IAA and GA were 33.9%~51.2% higher) and gene expression (the LHY and TOC1 rhythmic genes were 131.97%~165.81% higher). When an exogenous additive agent (SNP or MJ) was applied after drought, the negative effects of drought on growth were effectively alleviated (the tree height growth of D110 increased from 22.76% to 22.32% in comparison to drought conditions); meanwhile, the height growth of D110 plants was significantly higher than that of their parents. Further results of physiological indexes and the expression of related key gene changes in response to SNP or MJ also indicated that D110 plants can recover faster from drought than their parents after application of SNP or MJ. This article provides new ideas for revealing the heterosis mechanism of the drought resistance of interspecific F1 hybrids and supplies effective measures for improving drought resistance in F. mandshurica.
Acoustic Roughness Measurement of Railway Tracks: Running Surface Detection and Compensation of Lateral Movements for Optical Measurements on a Train
Authors: Mauz Florian , Wigger Remo , Griesbaum Loris , Wahl Tobias , Kuffa Michal , Wegener Konrad 
Published: June 2023

Rolling noise is a significant contributor to railway noise. Wheel and rail roughness are decisive for the emitted noise level. An optical measurement method installed on a moving train is suitable for closer monitoring of the rail surface condition. A measurement setup based on the chord method requires the sensors to be positioned in a straight line along the direction of measurement and in a stable lateral position. Measurements should always be performed within the shiny and uncorroded running surface, even when there are lateral movements of the train. In this study, concepts for the detection of the running surface and the compensation of lateral movements are investigated in a laboratory setting. The setup consists of a vertical lathe with a ring-shaped workpiece that incorporates an implemented artificial running surface. The detection of the running surface based on laser triangulation sensors and a laser profilometer is investigated. It is shown that the running surface can be detected using a laser profilometer that measures the intensity of the reflected laser light. It is possible to detect the lateral position and the width of the running surface. A linear positioning system is proposed to adjust the lateral position of the sensors based on the running surface detection of the laser profilometer. When the lateral position of the measuring sensor is disturbed by a movement with a wavelength of 18.85 m, the linear positioning system can keep the laser triangulation sensor inside the running surface for 98.44% of the measured data points at a velocity of approximately 7.5 km h−1. The mean positioning error is 1.40 mm. By implementing the proposed system on the train, future studies can be conducted to examine the lateral position of the running surface as a function of the various operational parameters of the train.
Nouveaux indices d’occupations humaines anciennes sous le contournement routier de La Mure (Isère)
Authors: Argant Thierry , Lemaître Simon , Djerbi Hatem 
Published: June 2023

En préalable à la réalisation du dernier tronçon du contournement routier de La Mure (Isère), un site d’habitat daté de la transition du Néolithique final à l’âge du Bronze ancien a été fouillé sur le plateau matheysin. Un ensemble de 27 structures définit le plan d’un bâtiment à architecture de bois, qui se développe au centre d’un petit replat déterminé par une poche limoneuse héritée d’une moraine würmienne. D’une surface d’environ 35 m ² , il présente un plan quadrangulaire, légèrement trapézoïdal. Ce bâtiment fait
suite à plusieurs occupations plus anciennes, avec des indices de fréquentation dès le Mésolithique.
Sur les rives du lac du Bourget à la fin de l’âge du Bronze
Authors: Billaud Yves 
Published: June 2023

The archeological knowledge of the lake Le Bourget has long been limited to the lot of objects dredged with little regard for the
context on the Late Bronze Age lakeside settlements during the second half of the 19th century. Underwater surveys over the past two decades have resulted in a review of the observations of precursors of underwater archeology and allow to clarify the area and the conservation status of the sites. On several of them, and contrary to what was conventionally accepted, thick sedimentary
sequences are present. Stratigraphic excavations and tree-ring dating are used to define several phases of occupation from -1068 to -805, interspersed by more or less important transgressive pulsations for which sedimentological and palynological studies provide clarification.
Data were obtained on the forms of habitat, which are not stereotyped unlike the lakeshore settlements of the Swiss Plateau. For two sites, indications were obtained on the internal evolution. A model of the lake shores occupation begin to be documented, with a possibility of functional specialization of the sites. Various studies (carpology, parasitology, organic geochemistry…) give early indications on the land-use modalities and its evolution. At least, the abandonment of lacustrine shores no longer appears to be linked mechanically to climatic pejoration, but rather to the conjunction of unfavorable factors.
Effect of the identical training process on the functional state of high-level sprint swimmers of both genders
Authors: Mykhaliuk Yevhen , Horokhovskyi Yehor , Bosenko Anatolii , Orlyk Nadiia , Topchii Mariia 
Published: June 2023

Purpose: to study the effect of an identical training process on the functional state of high-level sprint swimmers of both genders.
Material and methods. The heart rate variability indices, central hemodynamic parameters and PWC170/kg measurements were compared between 86 male and 42 female swimmers with sports qualifications from first-class athlete to Master of Sports International Class, and separately, – between 38 males and 9 females (Masters of Sports and Masters of Sports International Class), 28 males and 16 females (Candidates for Masters of Sports), and 22 males and 17 females (first-class athletes).
The results. In the general group (86 males vs. 42 females) only the greater value of PWC170/kg in males by 12.64 % (p<0.001) was revealed, without any differences in heart rate variability and central hemodynamics. Masters of Soprts and Masters of Sports International Class, as well as Candidates for Masters of Sports, didn't have gender differences in all indicators studied. In first-class athletes, there were no gender differences in heart rate variability and central hemodynamic parameters, except for PWC170/kg, which in males was greater by 11.27 % (p=0.036).
Conclusions. A comparison of 86 male and 42 female swimmers with sports qualifications from first-class athlete to Master of Sports International Class, who differed by age and training experience, showed no significant differences in HRV and central hemodynamic parameters except for PWC170/kg, which was 12.64 % higher in males (p<0.001). There were no significant differences between all studied indices in 38 male and 9 female swimmers with sports qualifications Master of Sports and Master of Sports International Class, with no differences in age or training experience. Comparison of 28 male and 16 female swimmers with sports qualification Candidate for Master of Sports, not differing by age and training experience showed no significant differences in HRV and central hemodynamic parameters, except for PWC170/kg, which was greater in males by 11.27 % (p=0.034). In 22 male and 17 female swimmers with sports qualification first-class athlete, not differing by age (males have greater training experience) there were no differences between all studied indices.
Obesity and depression: the course of depressive disorders depending on the body mass index, the role of physical activity and cognitive-behavioral therapy for their correction
Authors: Kiro Ludmyla , Zak Maksym , Chernyshov Oleh , Sverdlova Mziia 
Published: June 2023

Purpose: to establish the relationship between the severity of the course of depressive disorders and body mass index in patients with non-alcoholic fatty liver disease on the background of abdominal obesity, the role of physical activity and cognitive-behavioral therapy for their correction.
Materials and methods. 272 people (136 women and 136 men) were examined. The patients were divided into two clinical groups: 1st group – 90 people with non-alcoholic fatty liver disease and overweight (average body mass index =27.5±1.31 kg/m2), who followed only dietary recommendations and a complex physical exercises; 2nd group - 92 people with non-alcoholic fatty liver disease and abdominal obesity of the 1st degree (average body mass index =31.74±1.03 kg/m2), who additional underwent a 6-month course of cognitive-behavioral therapy. The control group consisted of 90 people with normal body weight (average body mass index =22.41±1.43 kg/m2). The Beck scale was used to assess the presence of depression.
Results. Depression in patients of the 1st and 2nd groups was registered in 2.3 times (x2=28.105, p=4.762e-10<0.05) and 2.6 times more often (x2=12.019, p=0.007<0.05), than in the control group. Mild depressive disorders in 1.9 times (D=0.304, p=0.032<0.005) more often recorded in young women (up to 45 years old). Patients of the 2nd group, who additionally received a course of CBT, recorded a decrease in the number of depressive disorders of moderate severity by 3.33 times (D=0.1837, p=0.0133), compared to the patients of the 1st group.
Conclusions. Gender-age characteristics and weight affect the severity of depressive disorders in obese patients. To reduce the number of depressive disorders and optimize body mass index, it is mandatory to use combined treatment in the form of aerobic exercises and cognitive-behavioral training.
Aggregation Activity of Platelets in Children by Photo-Optical Method on the Aggregometer "Solar" AR2110
Authors: Дмитриев В.В. , Борисенок М.Б. , Мычкова Г.Н. , Липай Н.В. 
Published: June 2023

Цель. Определить у детей показатели агрегационной активности тромбоцитов фотооптическим методом Born на агрегометре «Солар» АР2110 и оценить взаимосвязь полученных результатов с агрегационной активностью тромбоцитов, зарегистрированной в параллельных исследованиях с использованием импедансного агрегометра Multiplate. Материалы и методы. Исследуемую группу составили 36 практически здоровых детей в возрасте от 5 до 16 лет, плановое обследование которых проведено в порядке прохождения ежегодного медосмотра перед началом учебного года или перед выполнением инвазивных хирургических процедур. Обследование одобрено этическим комитетом Центра детской онкологии и иммунологии и выполнено после подписания родителями (законными представителями) детей информированного согласия. Результаты. Отсутствие возрастных (от 3 до 16 лет) различий агрегации тромбоцитов позволило определить условную возрастную норму, охватывающую диапазон значений для анализируемых показателей в пределах 5–95-го процентилей для оценки агрегации тромбоцитов, индуцированной АДФ в конечной концентрации 2,5×10-6 М/л и адреналином в конечной концентрации 5,0×10-6 М/л на оптическом агрегометре «Солар» АР2110. Заключение. Для здоровых детей в возрасте от 3 до 16 лет минимальное значение агрегационной активности, индуцированной АДФ 2,5×10-6 М/л составляет 58%, минимальное значение нормы агрегационной активности, индуцированной адреналином 5,0×10-6 М/л, – 60%.
Purpose. To determine the indicators of platelet aggregation activity in children using the Born photo-optical method on the Solar AR 2110 aggregometer and to assess the relationship of the results obtained with the platelet aggregation activity recorded in parallel studies using the Multiplate impedance aggregometer. Materials and methods. The study group consisted of 36 apparently healthy children aged 5 to 16 years, whose planned examination was carried out in order to undergo an annual medical examination before the start of the school year or before performing invasive surgical procedures. The examination was approved by the ethical committee of the Center for Pediatric Oncology and Immunology and was carried out after the parents (legal representatives) of the children signed their informed consent. Results. The absence of age-related (from 3 to 16 years) differences in platelet aggregation made it possible to determine a conditional age norm covering the range of values for the analyzed parameters within 5–95 percentiles for assessing platelet aggregation induced by ADP at a final concentration of 2.5×10-6 M/L and epinephrine at a final concentration of 5.0×10-6 M/L on the SOLAR AR2110 optical aggregometer. Conclusion. For healthy children aged 3 to 16 years, the minimum value of aggregation activity induced by ADP 2.5×10-6 M/L is 58%, the minimum value of the norm of aggregation activity induced by adrenaline 5.0×10-6 M/L is 60%.
Algorithm for the Management of Women in Rh Conflict Pregnancy
Authors: Дашкевич Э.В. , Пешняк Ж.В. , Белуга М.В. , Еремин В.Ф. , Новак Л.В. , Курлович И.В. 
Published: June 2023

Проведено исследование по идентификации гена RHD плода в крови матери у 60 беременных резус-отрицательных женщин и подклассов Ig G1 и G3 у 67 резус-отрицательных беременных женщин. Данные исследования направлены на профилактику осложнений при резус-конфликтной беременности.
A study was conducted to identify the fetal RHD gene in the mother’s blood in 60 and Ig G1 and G3 subclasses in 67 Rh-negative pregnant women. These studies are aimed at preventing complications in Rh-conflict pregnancy.
High-Speed Freezing of Plasma to Improve the Efficiency of Plasma Production for Medical Use in the Republic of Belarus
Authors: Дворецкова М.А. , Новик А.В. , Мятников А.С. , Петровский А.В. , Буко И.В. 
Published: June 2023

В организациях службы крови Республики Беларусь плазма производится из цельной донорской крови методом центрифугирования и методом афереза для удовлетворения потребностей пациентов в качественной и безопасной свежезамороженной плазме (СЗП), с целью производства лекарственных средств, медицинских изделий, реагентов и диагностических стандартов. Критерием показателя качества плазмы является активность в ней фактора свертывания крови VIII (фактора VIII), который сохраняется в регламентированных количествах в процессе заготовки и производства, карантинного контролируемого хранения, высокоскоростного замораживания и правильного размораживания для медицинского применения. В соответствии с требованиями производственной трансфузиологии замораживание плазмы проводится не более 60 минут. Статья содержит результаты валидации замораживания различных объемов плазмы до температуры минус 30 °С и ниже внутри контейнера с плазмой с использованием быстрозамораживателя CSF61: время замораживания составило не более 20 минут. Статья имеет практико-ориентированный характер для специалистов в производственной трансфузиологии. Уменьшение времени замораживания плазмы повысит эффективность производства ее для медицинского применения и позволит сократить стоимость плазмы за счет снижения энергозатрат на производство дозы СЗП.
In the Belarusian Blood Services plasma is produced from whole donor blood by centrifugation and apheresis to satisfy the needs of patients in quality and safe fresh frozen plasma (FFP), for the production of drugs, medical devices, reagents and diagnostic standards. Criterion indicator of quality plasma is the activity in it of clotting factor VIII (FVIII), which is preserved in regulated amounts during preparation and production, quarantine controlled storage, high-speed freezing and correct thawing for medical use. In accordance with the requirements of Belarusian Blood Services freezing of plasma is carried out not more than 60 minutes. The article contains the results of validation of freezing various volumes of plasma to minus 30 °С and below in a plasma container using a CSF61 rapid freezer: the freezing time was no more than 20 minutes. The article has a practice-oriented character for specialists of Blood Services. Reducing the time of freezing plasma will increase the efficiency of its production for medical use and will reduce the cost of plasma due to lower energy costs of producing a dose of FFP.
Ruptured ulcerated and inflammed gout tophi with deep soft tissue infection of left foot – when rheumatology meets surgery: a case report treated with local ozone therapy
Authors: Marinova Polina Georgieva 
Published: June 2023

Abstract
Tophaceouse gout is a rare condition and chronic complication of gout due to storage of derivates of uric acid – crystals of monosodium urate, accompanied by lipids, mucopolisaharides matrix and proteins. Rheumatology meets the surgery in cases of rupture, ulceration and inflammation of tophi with complication with severe soft tissue infection, sepsis, large swelling, destruction of affected joints and periphery neuropathy chronic pain. Spontaneous or traumatic perforation and ulceration of tophi are rare conditions, that’s why there no any rheumatology or surgical guideline for management of that condition. We present a case report of male patient with posttraumatic perforated gout tophus and soft tissue secondary infection of left foot. He was treated with standard surgical debridement and local ozone therapy with stabilized ozonides over wound surface. That article presents a pioneer experience in the treatment of complicated tophaceouse gout with topical administration of ozonated olive oil with vitamin E and shows the effect of that treatment in progress.
Endocan as an Early Predictor of Endothelial Dysfunction and Atherosclerosis in Egyptian Patients with Rheumatoid Arthritis.
Authors: Gadow Souzan Ezzat , El-Banna Hanaa S , Abd Elwahab Shaimaa A , AGaber Rasha A , Shaban Ekhlas A , El-Salawy Alaa M 
Published: June 2023

Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease. Inflammation leads to endothelial cells activation. Activated endothelial cells with increased leukocytes adhesion molecules expression, which can induce endothelial dysfunction (ED) and atherosclerosis.
Aim: to measure the serum level of Human endothelial cell-specific molecule-1 (endocan) in patients with rheumatoid arthritis and to evaluate its relation to endothelial dysfunction and atherosclerosis.
Materials and methods: the study included 30 consecutive RA patients, and 30 healthy control subjects. RA disease activity was measured by the DAS-28 score. Serum endocan was measured by enzyme-linked immunosorbent assay (ELISA). The collected data were statistically analyzed using SPSS program version 16.
Results: There was a significant elevation in Endocan level in RA patients (1.81 ± 0.66 ng/ml) compared to control group (1.41 ± 0.59ng/ml) (P= 0.012). Serum endocan levels showed significant positive correlation with disease activity score-28(DAS-28), ESR, CRP, LDL and carotid intima media thickness (cIMT) (P = 0.015, 0.004, <0.001, 0.008, 0.005 respectively). Linear regression analysis revealed that the serum endocan level, age and disease activity were independent predictors for cIMT, and atherosclerosis development in RA patients.
Conclusion: Endocan is a useful marker to predict endothelial dysfunction and atherosclerosis in patients with rheumatoid arthritis.
Okul Öncesi Çocuğa Sahip Annelerin Ebeveyn Öz Yeterliklerinin İncelenmesi
Authors: DEMİRDÖVEN Bilge , ÖZYÜREK Arzu 
Published: June 2023

Çalışmada okul öncesi yaş grubu çocuğa sahip annelerin ebeveyn öz yeterliklerinin
incelenmesi amaçlanmıştır. Araştırmada ilişkisel tarama yöntemi kullanılmış, çalışma
grubuna uygun örnekleme yöntemiyle belirlenen 236 anne katılmıştır. Veri toplamada
bireysel form ve Yenilenmiş Berkeley Ebeveyn Öz Yeterlik Ölçeğinden (YBEÖYÖ), verilerin
analizinde ise t testi ve ANOVA kullanılmıştır. Bulgulara göre annelerin ebeveyn öz
yeterliklerinin yüksek olduğu, YBEÖYÖ puanlarının çocuğun cinsiyeti ve annenin yaşı ile
anlamlı bir fark oluşturmadığı; YBEÖYÖ ebeveynliğe özgü stratejiler puanı ile çocuğun okula
gitme süresi arasındaki farkın anlamlı olduğu; çocuğun doğum sırası, annenin öğrenim
durumu ve annenin mesleği ile YBEÖYÖ puanları arasındaki farkın anlamlı olduğu
saptanmıştır.
IQRA’ SEBAGAI BENTUK LITERASI DALAM ISLAM
Authors: H. Mansyur Masykur 
Published: June 2023

Ketika pertama kali al-Qur’an diturunkan, kata pertama yang diwahyukan Allah melalui Malaikat Jibril untuk dilafalkan oleh baginda Nabi Muhammad saw adalah kata Iqra’. Kata Iqra’ biasa diterjemahkan dengan “bacalah”. Pengertian ini sesuai dengan kata Qara’a itu sendiri yang pada awalnya memang mempunyai arti “menghimpun”. Al Qur'an sering menggunakan kata Qara'a dalam berbagai ayatnya. Ketika menerima kalimat tersebut Nabi Muhammad saw gemetar dan mengatakan tidak bisa membaca. Walaupun demikian dengan turunnya ayat ini menunjukkan betapa pemuliaan dan penilaian yang tertinggi kepada kepandaian membaca sekaligus menulis berbagai ilmu pengetahuan. Bacalah! Dengan nama Tuhanmu yang telah mencipta. Menciptakan manusia dari segumpal darah. Bacalah! dan Tuhan engkau itu Maha Mulia. Dia yang mengajarkan dengan qalam. Mengajari manusia apa-apa yang dia tidak ketahui. Ayat-ayat ini menunjukkan Allah SWT mengajarkan kepada manusia berbagai ilmu, dibuka-Nya berbagai rahasia, diserahkan-Nya berbagai kunci untuk membuka perbendaharaan ilmu Allah, yaitu dengan qalam atau pena. Disamping lidah membaca, Allahpun mentakdirkan pula bahwa ilmu pengetahuan itu dapat dicatat. Nabi Muhammad saw adalah orang yang tidak pandai membaca dan menulis, akan tetapi beliau mengerti betapa pentingnya literasi. Literasi disini adalah kemampuan membaca dan menulis. Termasuk kemampuan berbicara, menghitung dan memecahkan masalah yang dihadapi.
SIKAP ADIL PENDIDIK DALAM PRESPEKTIF HADITS
Authors: Nofita Anna 
Published: June 2023

Pendidik memiliki peran yang penting dalam memberikan pengaruh terhadap peserta didiknya. Oleh karena itu perlu adanya kepribadian baiklah yang harus dimiliki oleh seorang pendidik, salah satunya yaitu dengan bersikap adil. Tujuan penelitian ini untuk mengetahui salah satu etika pendidik yaitu adil berdasarkan hadits yang diriwayatkan oleh Imam Bukhari. Penelitian yang dipakai adalah dengan metode kepustakaan (library research). Data tersebut diperoleh dari kitab yang relevan, kitab-kitab hadits, dan buku-buku pendidikan islam buku pendidikan. Kemudian dianalisis menggunakan teknik analisis deskriptif. Dalam penemuan haditsnya penulis menggunakan metode takhrij hadits. Dari hasil penelitian, hadits riwayat Imam Bukhari tentang salah satu etika pendidik yaitu adil jika dilihat dari segi kualitas dapat dinilai mempunyai kualitas yang shahih, dikarenakan sanadnya bersambung kepada Rasulullah dan terhindar dari syudzuz atau suatu kejanggalan karena adanya perbedaan ulama.