bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of the interaction between BDNF rs7103411 gene polymorphism and social activities on mild cognitive impairment in community-dwelling elderly adults
Authors: Tan Zhenkun , Ping Junjiao , Zhang Ying , Kong Chuijia , Luo Jiali , Liu Xinxia 
Published: January 2025

ObjectiveTo investigate the correlation between BDNF gene polymorphism, BDNF levels, and susceptibility to mild cognitive impairment (MCI).MethodsIn this study, we investigated 107 elderly adults individuals from a community in Zhongshan, Guangdong Province, with an average age of 73.17 ± 7.081 years. The participants included 52 patients with Mild Cognitive Impairment due to Alzheimer’s Disease and 55 cognitively normal elderly adults control subjects. The two groups were matched based on gender, age, and education level. We assessed their cognitive functions and analyzed their genotypes and serum BDNF levels. Analysis of covariance (ANCOVA) was used to evaluate the differences in serum BDNF levels between the MCI group and the control group. Multivariate linear regression was utilized to analyze the association between BDNF levels and susceptibility to MCI, as well as cognitive functions. Multivariate logistic regression was employed to investigate the association between BDNF gene polymorphisms and the risk of developing MCI, along with their interactions.ResultsThe ANCOVA analysis indicated that there was no significant difference in serum BDNF levels between the MCI group and the control group (P &gt; 0.05). Correlation analysis revealed a negative correlation between Mini-Mental Status Examination (MMSE) total scores and MCI (r = -0.461, P = 0.001), with significant correlations observed in orientation (r = -0.420, P = 0.002). Multiple linear regression analysis showed that specific polymorphisms, including rs7103411 (CT+TT vs. CC), rs6265 (CT and CT+TT vs. CC), rs11030104 (AG and AG+GG vs. AA), and rs988748 (CG+CC vs. GG), were significantly associated with decreased serum BDNF levels (P &lt; 0.05). Multivariate logistic regression showed that rs7103411 polymorphism was associated with susceptibility to MCI; individuals with the CT or CC genotype had a 0.370 times lower risk of developing MCI compared to those with the TT genotype (OR = 0.370, 95% CI: 0.141-0.970, P = 0.043). A significant interaction was found between rs7103411 and social activity, which influenced the risk of developing MCI. Specifically, individuals with the CT or TT genotype of rs7103411 who engaged in social activities had a significantly lower risk of developing MCI (OR = 0.32, 95% CI: 0.117-0.878, P = 0.027).ConclusionThis study indicates that BDNF rs7103411、rs6265、rs11030104 and rs988748 are associated with decreased serum BDNF levels in MCI patients. Individuals carrying the TT genotype in the BDNF rs7103411 gene are associated with an increased susceptibility to MCI. Individuals with the rs7103411 CT or TT genotype who participated in social activities showed a significantly reduced risk of developing MCI, suggesting that the interaction between the BDNF rs7103411 genotype and social activity can help reduce the risk of MCI.
Outcomes and associated factors of cervical human papillomavirus infection among 608 women in Shenzhen, China, 2018–2023
Authors: Lv Zhenghan , He Xuesen , Li Zhiju , Yuan Yue , Zhou Xinyi , Tu Changqing , Yang Yinqi , Huang Yanshan , Yin Lili , Chen Huihui , Tao Yanling 
Published: January 2025

ObjectiveThis study aimed to uncover the patterns of Human papillomavirus (HPV) infection outcomes in women and assess the risk factors that may affect these outcomes.MethodsA retrospective study was conducted on 608 women who tested positive for HPV-DNA during their initial visit to the outpatient department of Shenzhen Longgang Central Hospital from 2018 to 2023 and who had subsequent HPV-DNA testing as part of their post-visit monitoring. The monitoring intervals were every 6 months. The rank sum test was used to analyze ranked data. The Kaplan–Meier method was used to analyze the turning negative time. Univariate analysis was performed using the log-rank test, and multivariate analysis was performed using the Cox model to analyze independent risk factors.ResultsThe results showed that the median age was 40.00 years (interquartile 33.00–47.00 years), the total conversion rate of the HPV-negative patients was 38.98%, and the median conversion time of the HPV-negative patients was 8.95 months (interquartile 4.20–16.175 months). Age, infection status and type of health insurance were significantly correlated with HPV outcome (p &lt; 0.05).ConclusionAmong women infected with HPV, the overall rate of negative HPV infection was 38.93%, and the duration of negative conversion was 8.95 months. The study revealed that age, HPV infection status, and type of medical insurance are independent predictors of the persistence of negative HPV test outcomes.
Values, attitude, and desire in organic food purchase intention in Mexico
Authors: Leyva-Hernández Sandra Nelly , Toledo-López Arcelia , Hernández-Lara Ana Beatriz , Arango-Ramírez Paola Miriam , Avendaño-Rito María del Carmen 
Published: January 2025

IntroductionThis investigation analyses the purchase intention for organic foods through the influence of the consumer’s values, attitude, and desire, how this attitude mediates the relationship between consumer values and purchase intention, and how consumer desire mediates the relationship between attitude and purchase intention.MethodsThe quantitative approach was used with a transversal type of research. Data was collected through a survey of 204 consumers of organic foods in Mexico. The analysis of these results was carried out through partial least squares structural equation modeling.ResultsOnly appearance consciousness and environmental awareness are the motivators of the goals to influence the behavior of consumers when attitude mediates the relationships. However, when attitude mediated the relationship, health consciousness and social awareness were not significant motivators of behavioral intention.DiscussionThis analysis serves as a basis for deepening the study of gastronomic tourism in rural areas such as Mexico since this type of food is sold in tourist places. The model proposed can be used as a theoretical framework for future studies. Marketers can also use the results in marketing strategies as community marketing in economies like Latin American countries.
Mobile-based in-home telerehabilitation compared with in-hospital face-to-face rehabilitation for elderly patients after total hip arthroplasty in China's level 1 trauma center: a noninferiority randomized controlled trial
Authors: Zhou Yang , Lyu Yiming , Wang Qiaojie , Ma Yanhong , Huang Lihua , Zhang Xin 
Published: January 2025

BackgroundTelerehabilitation is gaining popularity in European and American countries, but whether it can be successfully implemented in China still lacks support from clinical studies.ObjectiveThis trial aimed to determine if a home-based telerehabilitation method is clinically noninferior to standard in-hospital face-to-face rehabilitation for elderly patients with total hip arthroplasty (THA) in China.MethodsThis multicenter randomized controlled trial was conducted from January 2021 to June 2022 at The First Rehabilitation Hospital in Shanghai, Shanghai Jiao Tong University affiliated Sixth People's Hospital and Shanghai Tongji University affiliated Tenth People's Hospital. Sixty-four patients were recruited for this two-arm, single-assessor blinded, randomized controlled trial. The participants were randomly assigned to the in-home telerehabilitation group (TELE group) and the in-hospital physical therapist in-person group (PT group). The intervention consisted of a 12-week home-based rehabilitation program with video instructions and remote coaching on a mobile APP (TELE group). The PT group received a standard in-hospital rehabilitation intervention assisted by a physical therapist for one month and outpatient clinic for the next two months. Patients were evaluated at baseline, 4 weeks, and 12 weeks postoperatively employing functional tests (Timed Up &amp; Go test and Berg balance test) and self-reported questionnaires (Hip disability and Osteoarthritis Outcome Score (HOOS) and Short Form 12 (SF-12)).ResultsThere was no significant difference between the two groups for the demographic and clinical characteristics. 61 participants were analyzed (PT group: n = 31, women: 48.4% of participants; TELE group: n = 30, 33.3% of participants) whose median age was 70 and 69 years, in PT group (IQR: 63–73) and TELE group (IQR: 66–72) respectively. At 12 weeks follow-up evaluation, the main differences between the two groups regarding the HOOS gains, adjusted for baseline values, were close to zero (P &gt; 0.05). There was no significant difference in primary and secondary outcome measures between the two groups.ConclusionOur results showed the noninferiority of in-home telerehabilitation and advocated its application as a reliable alternative to in-hospital face-to-face rehabilitation for patients who underwent THA.Clinical Trial Registrationhttps://www.chictr.org.cn/, Chinese Clinical Trial Registry (Number: ChiCTR1900025825).
Polymerization characteristics of orthodontic adhesives: a study on degree of conversion
Authors: Almokaddam H. , Tuturov N. S. , Katbeh I. , Zahran M. , Takla Z. A. 
Published: January 2025

Relevance. Adhesive materials play a crucial role in orthodontic treatment. The introduction of universal bonding agents to the dental market offers greater flexibility in choosing adhesive protocols for clinical use. However, many studies evaluating the mechanical properties of adhesives, such as shear and tensile bond strength, fail to address the degree of conversion of polymerized bonding materials beneath brackets.Objective. To compare the degree of conversion between a universal adhesive system and a total-etch system for orthodontic applications.Materials and methods. The study compared the Transbond XT total-etch system (3M Unitek, USA) with the Tetric N-Bond Universal system (Vivadent Ivoclar, Liechtenstein). Four groups of five samples each (n = 5) were analyzed. Groups 1 and 2 involved polymerization without brackets, while Groups 3 and 4 involved polymerization under metal brackets (Gemini, 3M Unitek, USA). Spectra were recorded immediately after polymerization for 15 minutes using Fourier-transform infrared spectroscopy (FTIR). Statistical analysis included the Shapiro–Wilk test, analysis of variance (ANOVA), and Tukey's multiple comparison test, with a significance level of p < 0.05.Results. The mean degree of conversion in the control groups was 55.9% ± 0.44 for Group 1 and 66.72% ± 0.15 for Group 2. A reduction in conversion was observed in specimens polymerized under metal brackets compared to the control groups. The mean conversion in Group 3 was 36.02% ± 0.19, which was 1.1% lower than in Group 4 (37.1% ± 0.16).Conclusion. The universal adhesive Tetric N-Bond Universal demonstrated superior polymerization performance for orthodontic applications compared to the total-etch adhesive system.
Феномен инцелов в социальных сетях
Authors: Шестакова И.В. 
Published: January 2025

Феномен инцелов представляет собой сложное и многогранное социальное явление, получившее широкое распространение в интернете. В ходе анализа контента инцел-сообществ в социальных сетях, включая посты, мемы и комментарии. Выявлены ключевые темы: социальная критика, личные переживания, попытки самосовершенствования, юмористический контент и глобальные обобщения. Проведённый анализ показал, что инцел-сообщества характеризуются высокой эмоциональной напряжённостью, фатализмом и коллективным обсуждением социальных несправедливостей, при этом попытки позитивных изменений встречаются реже. Юмористический контент одновременно укрепляет внутреннюю идеологию сообщества и создаёт пространство для эмоциональной разрядки. Работа подчёркивает важность изучения социальных движений в интернете для понимания их влияния на участников и общество в целом.
The phenomenon of incels is a complex and multifaceted social issue that has gained significant traction on the internet. This study focuses on the analysis of incel community content in social networks, including posts, memes, and comments. Key themes identified include social critique, personal experiences, self-improvement efforts, humorous content, and global generalizations. The analysis revealed that incel communities are characterized by high emotional intensity, fatalism, and collective discussions of perceived social injustices, while efforts toward positive change are less frequent. Humorous content simultaneously reinforces the community's internal ideology and provides an outlet for emotional relief. The study highlights the importance of examining online social movements to better understand their impact on participants and society as a whole.
Анализ ливийского медиаландшафта
Authors: Дан Ц. 
Published: January 2025

На медиаландшафт Ливии глубоко влияет сложная и нестабильная ситуация. В последние годы ситуация в Ливии продолжает оставаться неспокойной, и существует множество проблем и переменных в политических, экономических и социальных аспектах, из-за которых среда ливийских СМИ также выглядит сложной и неопределенной. На политическом фронте конфликты и разногласия между политическими фракциями в Ливии все еще существуют, что приводит к серьезным проблемам политической стабильности страны. На экономическом фронте экономические проблемы Ливии становятся все более серьезными: бедность, безработица и другие проблемы усугубляют социальную нестабильность. С точки зрения развития самих СМИ ливийские медиа-организации сталкиваются со многими трудностями. Однако, несмотря на множество проблем и трудностей, средства массовой информации в Ливии по-прежнему пытаются играть должную роль.
The media landscape in Libya is deeply affected by the complex and unstable situation. In recent years, the situation in Libya has remained turbulent, and there are many problems and variables in the political, economic and social aspects, which make the Libyan media environment also appear complex and uncertain. On the political front, conflicts and disagreements between political factions in Libya still exist, causing serious problems for the country's political stability. On the economic front, Libya's economic problems are becoming increasingly serious, with poverty, unemployment and other problems exacerbating social instability. In terms of media development itself, Libyan media organizations are facing many difficulties. However, despite many problems and difficulties, the media in Libya is still trying to play its due role.
Дипфейк как угроза политической коммуникации
Authors: Михеев Н.И. 
Published: January 2025

в начале 2000 года, сложно было представить, что через 24 года у трёх из четырёх жителей России будет доступ к интернету. А пользоваться социальными медиа будут 73% населения. Такие данные приводит Datareportal в отчёте отчете «Digital 2024: Country Headlines Report» [Datareportal]. Подобная статистка говорит о том, что уровень цифровизации почти за одну четверть века текущего столетия значительно вырос. Чем больше новых цифровых платформ, систем и процессов, тем больше появляется новых цифровых инструментов. Одним новым, ещё малоисследованным инструментом служит термин – дипфейк. Целью настоящего исследования является теоретическое и сущностное изучение понятия дипфейка. Нового инструмента, с помощью которого возможно повлиять на политическую коммуникацию. Задачами исследования являются: изучить и раскрыть понятие дипфейка и его разновидностей, определить кто и каким образом может использовать дипфейки в политической коммуникации, оценить риски и угрозы дифейков, и предложить пути решения данной цифровой угрозой. Результаты. В ходе работы были выявлены сущность и основновные виды дипфейков, приведены примеры политических угроз с применением дипфейков, сделан вывод и дано предложение о необходимости разработки нормативно правовой базы, устанавливающей и регламентирующей работу создание дипфейков.
вack in the early 2000s, it was difficult to imagine that within 24 years, three out of four Russians would have access to the internet. And 73% of the population would use social media. These statistics are provided by Datareportal in its report "Digital 2024: Country Headlines Report". Such figures indicate that the level of digitization has increased significantly over the last quarter of the current century. With the emergence of new digital platforms, systems, and processes, new digital tools have also emerged. One such new tool, which is still relatively unexplored, is deepfake. The purpose of this study is to theoretically and essentially study the concept of deepfake, a new tool that can be used to influence political communication. The objectives of the research are: to study and reveal the concept of deepfake and its varieties, to determine who can use deepfakes in political communication and how, to assess the risks and threats of deepfakes, and to propose ways to solve this digital threat. Results. In the course of the work, the essence and main types of deepfakes were identified. Examples of political threats using deepfakes are given, a conclusion is drawn and a proposal is made on the need to develop a regulatory framework that establishes and regulates the creation of deepfakes.
MUI'S STRATEGIC ROLE IN ISLAMIC BANKING: An Overview
Authors: Adnan Mohammad , Uyuni Badrah , Mahfuz Mahfuz , Anim Sarbini , Kohari Khalis 
Published: January 2025

Abstract

This study explores the strategic role of the Indonesia Ulema Council (MUI) in the development and supervision of Islamic banking in Indonesia, with a focus on the contribution of the National Sharia Council (DSN MUI). MUI functions as a guardian of sharia principles, provides fatwas, conducts supervision, and plays a role in the development of sharia banking products. This study identifies challenges such as legal ambiguity and dualism of authority between the MUI, the Financial Services Authority (OJK), and Bank Indonesia (BI), as well as assessing the effectiveness of the MUI in carrying out its role. The findings show that although MUI contributes significantly to maintaining sharia compliance, these challenges affect its effectiveness. Using a qualitative approach, this review provides practical recommendations including regulatory adjustments to reduce legal ambiguity, increased coordination between MUI, OJK, and BI, improvement of supervision and accreditation mechanisms, and expansion of education and socialization regarding Islamic banking. With the implementation of this recommendation, it is hoped that MUI can strengthen its role in supporting sustainable and harmonious growth of Islamic banking.

Abstract

This study explores the strategic role of the Indonesia Ulema Council (MUI) in the development and supervision of Islamic banking in Indonesia, with a focus on the contribution of the National Sharia Council (DSN MUI). MUI functions as a guardian of sharia principles, provides fatwas, conducts supervision, and plays a role in the development of sharia banking products. This study identifies challenges such as legal ambiguity and dualism of authority between the MUI, the Financial Services Authority (OJK), and Bank Indonesia (BI), as well as assessing the effectiveness of the MUI in carrying out its role. The findings show that although MUI contributes significantly to maintaining sharia compliance, these challenges affect its effectiveness. Using a qualitative approach, this review provides practical recommendations including regulatory adjustments to reduce legal ambiguity, increased coordination between MUI, OJK, and BI, improvement of supervision and accreditation mechanisms, and expansion of education and socialization regarding Islamic banking. With the implementation of this recommendation, it is hoped that MUI can strengthen its role in supporting sustainable and harmonious growth of Islamic banking.
مفهوم الفيء وتطور دلالاته في عصر النبوة والخلفاء الراشدين
Authors: Al-Momani Mohammad Khaled 
Published: January 2025

الأهداف: هدفت الدراسة الحالية إلى التعرض إلى مفهوم الفيء في اللغة والاصطلاح، وتطور معناه النظري والتطبيقي في عصر النبوة والخلفاء الراشدين، كما هدفت الدراسة التطرق للتطبيقات العملية لمفهوم الفيء الذي صحبه بعض الاجتهادات والمستجدات والاستثناءات في عصر النبوة والخلفاء الراشدين.
المنهجية: استخدمت الدراسة المنهج التحليلي من جمع المعلومات بطريقة الاستقصاء استناداً إلى الآيات القرآنية الكريمة، والسنة النبوية الشريفة، والروايات التاريخية المتضمنة ما وقع من أحداث في عصر النبوة والخلفاء الراشدين، التي تميزت بالجهاد وبدء الفتوحات الإسلامية، ثم فهمها، وفرزها، وتصنيفها، وتحليلها بما يتوافق مع الفترة الزمنية من جهة، وكيفية تطبيقها عملياً من جهة ثانية، واستخراج النتائج.
النتائج: أشارت النتائج إلى أنّ مفهوم الفيء ما عاد ورجع لأيدي المسلمين من الكفار صلحاً أم عنوة من أراضٍ وأموال وممتلكات وغيرها. كما أشارت النتائج أن تطور مفهوم الفيء جاء وفق الاجتهادات في دلالته بحسب الفترة الزمنية، فقد جاء بمعنى الغنيمة، والجزية، الخراج، كما جاء بمعنى الجزية والخراج معاً كما شمل الجزية والخراج وعشور التجارة والصواف. كما خلصت النتائح أن الرسول محمد- صلى الله عليه وسلم- اجتهد في تطبيقه لمفهوم الفيء وفقاً للسياسة الشرعية التي تعود بالمنفعة على المسلمين، وتبعه أبو بكر- رضي الله عنه- في ذات النهج، إلا أن الخليفتين عمر بن الخطاب، وعثمان بن عفان رضي الله عنهما؛ تعاملا مع الفيء بوقف الأرض، وتزويد بيت المال المسلمين بريعها.
الخلاصة: إنَّ التوضيح الدلالي والتطوري لمفهوم الفيء لمعناه وفقاً للمستجدات المتعلقة في اختلاف الزمان والمكان في عصر النبوة والخلفاء الراشدين من الجانبين النظري والعملي، يزيل اللبس في تطبيقه في ضوء الظروف والمستجدات والمرحلة الزمنية المرتبطة بهما.